File S2 contains the genes that are predicted to be targeted by novel drugs for Matador. 1:[DB02466 DB07543] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 2:[DB02466 DB11730] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation CDK4;RARG GO:0043065| positive regulation of apoptotic process RARG;CDK4 GO:0045596| negative regulation of cell differentiation RARG;CDK6 GO:0010468| regulation of gene expression CDK6;CDK4;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;CDK4 GO:0008285| negative regulation of cell proliferation RARG;CDK6 3:[DB02466 DB00413] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD3;DRD2 GO:0008284| positive regulation of cell proliferation ADRA2A;DRD3;RARG;HTR2B;HTR1A;HTR2A 4:[DB02466 DB01224] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01224|Quetiapine HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP3A4;CYP2C19;CYP2D6;ABCB1 common genes common pathways GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0008284| positive regulation of cell proliferation RARG;HTR1A;HTR2A;ADRA1D;ADRA2A;DRD3;CHRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RARG GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG 5:[DB02466 DB06605] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 6:[DB02466 DB01179] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;RARG 7:[DB02466 DB05127] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05127|ANA971 TLR7 common genes common pathways 8:[DB02466 DB01148] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 9:[DB02466 DB01594] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways 10:[DB02466 DB00196] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways 11:[DB02466 DB02789] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0008285| negative regulation of cell proliferation SULT2B1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG 12:[DB02466 DB08911] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;RARG GO:0060324| face development MAP2K1;RARG GO:0010628| positive regulation of gene expression RARG;MAP2K1 13:[DB02466 DB01415] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 14:[DB02466 DB00940] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00940|Methantheline CHRM1;HRH2 common genes common pathways GO:0048732| gland development HRH2;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRM1 15:[DB02466 DB00816] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00816|Orciprenaline ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 16:[DB02466 DB00543] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression DRD1;RARG;SLC6A4 GO:0008284| positive regulation of cell proliferation DRD3;HTR2A;RARG;CHRM1;ADRA2A;ADRA1D;HTR1A;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD3;DRD2 17:[DB02466 DB00936] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043065| positive regulation of apoptotic process RARG;PTGS2 18:[DB02466 DB01165] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043065| positive regulation of apoptotic process RARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A 19:[DB02466 DB01618] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation HTR1A;CHRM1;HTR2A;RARG GO:0008285| negative regulation of cell proliferation DRD2;RARG 20:[DB02466 DB01023] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0043010| camera-type eye development CACNA1C;RARG GO:0006355| regulation of transcription, DNA-dependent NR3C2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C2 GO:0006351| transcription, DNA-dependent NR3C2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C2;RARG 21:[DB02466 DB01029] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0043065| positive regulation of apoptotic process JUN;RARG GO:0008284| positive regulation of cell proliferation RARG;JUN GO:0045944| positive regulation of transcription from RNA polymerase II promoter JUN;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;JUN GO:0043066| negative regulation of apoptotic process JUN;RARG GO:0008285| negative regulation of cell proliferation JUN;RARG GO:0006351| transcription, DNA-dependent RARG;JUN 22:[DB02466 DB00866] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG GO:0008284| positive regulation of cell proliferation HTR1A;RARG 23:[DB02466 DB06233] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0035264| multicellular organism growth MTOR;RARG GO:0010628| positive regulation of gene expression MTOR;RARG GO:0008361| regulation of cell size MTOR;RARG GO:0031641| regulation of myelination RARG;MTOR 24:[DB02466 DB00843] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;RARG GO:0060041| retina development in camera-type eye RARG;ACHE 25:[DB02466 DB00987] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways 26:[DB02466 DB14011] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0008285| negative regulation of cell proliferation RARG;PPARG;CYP1B1;OPRM1;PTGS2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0032526| response to retinoic acid PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TRPV4;PPARG;TRPV1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process CAT;PTGS2;GPX1;SOD1;RARG;HMGCR GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0010628| positive regulation of gene expression TRPV4;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR2A;HMGCR;CHRNA7;PTGS2;HTR1A GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;PPARG;PTGS2;SOD1;SMPD1;RARG;CNR1;IDO1 27:[DB02466 DB08877] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation JAK2;RARG GO:0043065| positive regulation of apoptotic process JAK2;RARG GO:0008284| positive regulation of cell proliferation RARG;JAK2 28:[DB02466 DB11641] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 29:[DB02466 DB00292] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways 30:[DB02466 DB01218] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways 31:[DB02466 DB01099] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01099|Flucytosine DNMT1 common genes common pathways GO:0010468| regulation of gene expression RARG;DNMT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;RARG GO:0006351| transcription, DNA-dependent RARG;DNMT1 GO:0006355| regulation of transcription, DNA-dependent DNMT1;RARG GO:0010628| positive regulation of gene expression DNMT1;RARG 32:[DB02466 DB01204] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;CYP1B1 GO:0043065| positive regulation of apoptotic process RARG;TOP2A;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;RARG 33:[DB02466 DB06267] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways 34:[DB02466 DB01198] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0043065| positive regulation of apoptotic process TSPO;RARG 35:[DB02466 DB00854] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 36:[DB02466 DB14050] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;RARG 37:[DB02466 DB00622] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;CHRM1;RARG GO:0043010| camera-type eye development CACNA1C;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 38:[DB02466 DB01232] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01232|Saquinavir pol;CYP3A7;CYP3A5;CYP3A4;CYP11A1;CYP2C8;CYP2D6;ORM1;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;ABCC1;ABCC2;SLCO2B1;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 39:[DB02466 DB00370] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0010628| positive regulation of gene expression SLC6A4;RARG;DRD1 GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR2A;DRD3;ADRA1D;HTR2B;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;ADRB2;RARG;DRD3 40:[DB02466 DB01118] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0032526| response to retinoic acid RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter THRB;THRA;PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;THRB;RARG GO:0006351| transcription, DNA-dependent THRA;THRB;PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG;THRA;THRB GO:0008285| negative regulation of cell proliferation PPARG;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;THRB;THRA;RARG GO:0006355| regulation of transcription, DNA-dependent THRA;THRB;PPARG;RARG GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0071300| cellular response to retinoic acid PPARG;RARG 41:[DB02466 DB00392] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE GO:0008284| positive regulation of cell proliferation CHRM1;RARG 42:[DB02466 DB00768] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;S100A1 GO:0043065| positive regulation of apoptotic process S100B;RARG GO:0008284| positive regulation of cell proliferation S100B;RARG;S100A13 43:[DB02466 DB00483] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0060041| retina development in camera-type eye RARG;ACHE GO:0008284| positive regulation of cell proliferation CHRM1;RARG 44:[DB02466 DB00300] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;NME2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NME2;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NME2 GO:0008285| negative regulation of cell proliferation NME1;RARG GO:0006351| transcription, DNA-dependent RARG;NME2 45:[DB02466 DB00960] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 46:[DB02466 DB14568] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways 47:[DB02466 DB09273] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PDE2A GO:0008285| negative regulation of cell proliferation ADORA2A;RARG 48:[DB02466 DB00290] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways 49:[DB02466 DB14597] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14597|Lanadelumab KLKB1 common genes common pathways 50:[DB02466 DB00945] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0043066| negative regulation of apoptotic process PRKAA2;RPS6KA3;PTGS2;PRKAA1;HSPA5;IKBKB;NFKB1;NFKBIA;RARG;ALB;TP53 GO:0010628| positive regulation of gene expression PRKAA1;PRKAB1;PRKAG1;RARG;TP53 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RPS6KA3;RARG;TP53;NFKB1;NFKBIA;IKBKB;NFKB2 GO:0008284| positive regulation of cell proliferation PRKAA1;PTGS2;RARG GO:0006355| regulation of transcription, DNA-dependent PRKAA1;PRKAA2;RARG;TP53;NFKB2;NFKB1 GO:0043065| positive regulation of apoptotic process TP53;RARG;PTGS2 GO:0006351| transcription, DNA-dependent PRKAA1;PRKAA2;RARG;TP53;NFKB1;NFKB2 GO:0008285| negative regulation of cell proliferation PTGS2;TP53;RARG GO:0010468| regulation of gene expression RARG;NFKBIA;PRKAA2 GO:0032526| response to retinoic acid RARG;TP53 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP53;RARG;NFKB1;NFKB2 51:[DB02466 DB00296] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 52:[DB02466 DB01087] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;CYP1B1 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043010| camera-type eye development CYP1A1;RARG GO:0043065| positive regulation of apoptotic process CYP1B1;RARG 53:[DB02466 DB11753] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG 54:[DB02466 DB01124] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 55:[DB02466 DB00997] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;RARG;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;NOS1;RARG GO:0008284| positive regulation of cell proliferation AKR1C3;RARG GO:0043065| positive regulation of apoptotic process RARG;TOP2A;CYP1B1 GO:0043066| negative regulation of apoptotic process POR;NQO1;RARG;ALB 56:[DB02466 DB00266] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process NQO1;ALB;RARG GO:0060348| bone development RARG;VKORC1 57:[DB02466 DB11587] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11587|Etafedrine ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 58:[DB02466 DB14583] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent PGR;AR;RARG;NR3C1 GO:0008285| negative regulation of cell proliferation AR;RARG GO:0043401| steroid hormone mediated signaling pathway AR;PGR;NR3C1;RARG GO:0048608| reproductive structure development AR;RARG GO:0010468| regulation of gene expression AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1;AR GO:0006367| transcription initiation from RNA polymerase II promoter PGR;AR;NR3C1;RARG GO:0035264| multicellular organism growth RARG;AR GO:0010628| positive regulation of gene expression AR;RARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG;PGR;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;AR;NR3C1;RARG GO:0008284| positive regulation of cell proliferation AR;RARG GO:0060740| prostate gland epithelium morphogenesis RARG;AR 59:[DB02466 DB08867] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway AR;PGR;NR3C1;RARG GO:0008285| negative regulation of cell proliferation AR;RARG GO:0006351| transcription, DNA-dependent AR;PGR;RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG;AR;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG;AR GO:0010468| regulation of gene expression CYP1A2;AR;RARG GO:0048608| reproductive structure development RARG;AR GO:0010628| positive regulation of gene expression RARG;AR GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0035264| multicellular organism growth AR;RARG GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0008284| positive regulation of cell proliferation RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1;AR;PGR GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1;PGR;AR 60:[DB02466 DB01251] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways 61:[DB02466 DB09235] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C 62:[DB02466 DB04725] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG 63:[DB02466 DB00153] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0010628| positive regulation of gene expression VDR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;VDR GO:0006355| regulation of transcription, DNA-dependent RARG;VDR GO:0006351| transcription, DNA-dependent VDR;RARG GO:0043401| steroid hormone mediated signaling pathway VDR;RARG GO:0008285| negative regulation of cell proliferation VDR;RARG;CYP27B1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;RARG 64:[DB02466 DB00358] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0060041| retina development in camera-type eye ACHE;RARG GO:0008285| negative regulation of cell proliferation RARG;ADORA2A;BCHE GO:0006355| regulation of transcription, DNA-dependent ADORA2A;RARG 65:[DB02466 DB09256] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 66:[DB02466 DB09229] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0043010| camera-type eye development RARG;CACNA1C GO:0008284| positive regulation of cell proliferation RARG;ADRA1D;ADRA2A 67:[DB02466 DB09078] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;FGFR1 GO:0060349| bone morphogenesis RARG;FGFR3;FGFR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;FGFR2;RARG GO:0010468| regulation of gene expression CYP1A2;FGFR1;RARG GO:0048608| reproductive structure development RARG;FGFR2 GO:0010628| positive regulation of gene expression KIT;RARG;FGFR4 GO:0071300| cellular response to retinoic acid RARG;FGFR2 GO:0060348| bone development RARG;FGFR2 GO:0043066| negative regulation of apoptotic process FLT4;KDR;RARG GO:0035264| multicellular organism growth RARG;FGFR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;FGFR2 GO:0008284| positive regulation of cell proliferation FLT4;KDR;FGFR3;KIT;RARG;FGFR4;FLT1;FGFR1;FGFR2 GO:0006355| regulation of transcription, DNA-dependent FGFR1;RARG 68:[DB02466 DB00417] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 69:[DB02466 DB11691] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 70:[DB02466 DB00738] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 71:[DB02466 DB00882] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway RARG;ESR1 GO:0006351| transcription, DNA-dependent RARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;ESR1 72:[DB02466 DB01248] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I2 GO:0010468| regulation of gene expression BCL2;RARG GO:0008285| negative regulation of cell proliferation RARG;BCL2;CYP1B1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2 GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0043065| positive regulation of apoptotic process RARG;CYP1B1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0008284| positive regulation of cell proliferation RARG;BCL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2 GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0043066| negative regulation of apoptotic process RARG;BCL2 73:[DB02466 DB00497] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 74:[DB02466 DB08931] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0043010| camera-type eye development RARG;CYP1A1 75:[DB02466 DB00332] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 76:[DB02466 DB06780] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C2 GO:0006351| transcription, DNA-dependent NR3C2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C2;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C2 77:[DB02466 DB02750] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 78:[DB02466 DB06216] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RARG;ADRB2 GO:0008284| positive regulation of cell proliferation DRD3;RARG;HTR2A;ADRA2A;HTR2B;HTR1A GO:0048732| gland development RARG;HRH2 GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0010628| positive regulation of gene expression RARG;DRD1 79:[DB02466 DB00228] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 80:[DB02466 DB00663] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;RARG 81:[DB02466 DB01282] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01282|Carbetocin OXTR common genes common pathways 82:[DB02466 DB00477] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00477|Chlorpromazine DRD2;DRD1;HTR1A;HTR2A;ADRA1A;ADRA1B;HRH1;KCNH2;DRD1;DRD5;DRD3;DRD4;DRD5;HTR2C;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM3;SMPD1;CALM1;ORM1;ORM2;HTR6;HTR7;HRH4;CYP2D6;CYP1A2;CYP2E1;CYP3A4;BCHE;ALB;ABCB1;ABCB11 common genes common pathways GO:0043065| positive regulation of apoptotic process SMPD1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RARG GO:0008284| positive regulation of cell proliferation HTR1A;HTR2B;ADRA1D;ADRA2A;CHRM1;RARG;HTR2A;DRD3 GO:0010628| positive regulation of gene expression DRD1;RARG GO:0043066| negative regulation of apoptotic process HTR2B;RARG;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation DRD2;BCHE;ADRA1A;RARG 83:[DB02466 DB00226] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00226|Guanadrel SLC6A2 common genes common pathways 84:[DB02466 DB01373] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0001843| neural tube closure RARG;BMP4 GO:0043401| steroid hormone mediated signaling pathway BMP4;RARG GO:0060429| epithelium development RARG;BMP4 GO:0008285| negative regulation of cell proliferation BMP4;RARG GO:0010468| regulation of gene expression BMP4;RARG GO:0035116| embryonic hindlimb morphogenesis BMP4;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;BMP4 GO:0043066| negative regulation of apoptotic process BMP4;COMP;RARG GO:0003417| growth plate cartilage development COMP;RARG GO:0043010| camera-type eye development RARG;CACNA1C;BMP4 GO:0010628| positive regulation of gene expression RARG;BMP4 GO:0060348| bone development BMP4;RARG GO:0008284| positive regulation of cell proliferation S100A13;BMP4;RARG;S100B GO:0045944| positive regulation of transcription from RNA polymerase II promoter BMP4;RARG GO:0032331| negative regulation of chondrocyte differentiation RARG;BMP4 GO:0060173| limb development COMP;RARG GO:0043065| positive regulation of apoptotic process BMP4;S100B;RARG 85:[DB02466 DB09209] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 86:[DB02466 DB13179] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I2 GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG 87:[DB02466 DB01435] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG 88:[DB02466 DB00898] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008284| positive regulation of cell proliferation CHRNA7;RARG GO:0043010| camera-type eye development RARG;CACNA1C;CYP1A1 89:[DB02466 DB00197] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process GSTP1;PPARD;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0010628| positive regulation of gene expression RARG;PPARD GO:0006355| regulation of transcription, DNA-dependent ESRRA;PPARG;PPARA;RARG;PPARD;ESRRG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;ESRRA;ESRRG;SERPINE1;RARG GO:0008284| positive regulation of cell proliferation PPARD;RARG GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0048384| retinoic acid receptor signaling pathway ESRRG;RARG GO:0006351| transcription, DNA-dependent ESRRG;PPARD;RARG;PPARA;PPARG;ESRRA GO:0008285| negative regulation of cell proliferation PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARD;ESRRG;ESRRA;PPARG;PPARA GO:0010468| regulation of gene expression PPARA;RARG GO:0032526| response to retinoic acid PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;PPARG;PPARA;RARG;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARD;ESRRG;ESRRA;PPARG;PPARA 90:[DB02466 DB01186] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 GO:0008284| positive regulation of cell proliferation DRD3;HTR2A;RARG;ADRA2A;HTR1A;HTR2B;ADRA1D GO:0008285| negative regulation of cell proliferation RARG;DRD2;ADRA1A GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 91:[DB02466 DB11569] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11569|Ixekizumab IL17A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL17A;RARG 92:[DB02466 DB01032] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 93:[DB02466 DB00628] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0043065| positive regulation of apoptotic process TSPO;RARG 94:[DB02466 DB09089] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG GO:0043065| positive regulation of apoptotic process RARG;KCNMA1 GO:0043010| camera-type eye development RARG;CACNA1C GO:0008285| negative regulation of cell proliferation RARG;OPRM1 95:[DB02466 DB09570] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 96:[DB02466 DB08815] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0008284| positive regulation of cell proliferation HTR1A;ADRA2A;HTR2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG 97:[DB02466 DB00400] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 98:[DB02466 DB00468] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043010| camera-type eye development RARG;CYP1A1 99:[DB02466 DB00208] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0045596| negative regulation of cell differentiation P2RY12;RARG GO:0043066| negative regulation of apoptotic process RARG;MPO GO:0010468| regulation of gene expression CYP1A2;RARG 100:[DB02466 DB01021] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways 101:[DB02466 DB00824] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADORA3;ADORA2A;ADORA1 GO:0043066| negative regulation of apoptotic process RARG;ADORA1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;RARG 102:[DB02466 DB08906] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG 103:[DB02466 DB02546] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;HDAC1 GO:0006351| transcription, DNA-dependent HDAC6;HDAC8;HDAC2;HDAC3;HDAC1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;HDAC2;HDAC1;RARG;HDAC3 GO:0071300| cellular response to retinoic acid RARG;HDAC2 GO:0043066| negative regulation of apoptotic process HDAC2;RARG;HDAC1;HDAC3 GO:0006355| regulation of transcription, DNA-dependent HDAC2;HDAC8;HDAC6;RARG;HDAC1;HDAC3 GO:0008284| positive regulation of cell proliferation HDAC2;RARG;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;RARG;HDAC3;HDAC2 104:[DB02466 DB11124] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;RARG 105:[DB02466 DB09363] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways 106:[DB02466 DB00912] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARG GO:0032526| response to retinoic acid PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0008285| negative regulation of cell proliferation RARG;PPARG GO:0006351| transcription, DNA-dependent PPARG;RARG GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB 107:[DB02466 DB14010] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;RARG 108:[DB02466 DB14509] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0010628| positive regulation of gene expression GSK3B;RARG GO:0060070| canonical Wnt receptor signaling pathway GSK3B;RARG GO:0043066| negative regulation of apoptotic process RARG;GSK3B 109:[DB02466 DB00211] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;ADRA1D GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 110:[DB02466 DB08895] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;JAK2 GO:0008284| positive regulation of cell proliferation JAK2;RARG GO:0043065| positive regulation of apoptotic process RARG;JAK2 GO:0043066| negative regulation of apoptotic process ALB;RARG 111:[DB02466 DB01324] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01324|Polythiazide SLC12A3 common genes common pathways 112:[DB02466 DB14539] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006351| transcription, DNA-dependent NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0043066| negative regulation of apoptotic process RARG;ANXA1 GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0043065| positive regulation of apoptotic process RARG;ANXA1 113:[DB02466 DB00863] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0048732| gland development HRH2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008285| negative regulation of cell proliferation BCHE;RARG GO:0060041| retina development in camera-type eye ACHE;RARG 114:[DB02466 DB05885] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways 115:[DB02466 DB09204] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0008284| positive regulation of cell proliferation ADRA1D;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 116:[DB02466 DB01205] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways 117:[DB02466 DB09185] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 118:[DB02466 DB00285] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression RARG;SLC6A4 119:[DB02466 DB00708] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 120:[DB02466 DB00390] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways 121:[DB02466 DB00407] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 122:[DB02466 DB00822] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways 123:[DB02466 DB00215] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRM1 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0010468| regulation of gene expression CYP1A2;RARG 124:[DB02466 DB00250] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;MPO;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;RARG 125:[DB02466 DB00980] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 126:[DB02466 DB00241] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 127:[DB02466 DB00206] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;BIRC5 GO:0043066| negative regulation of apoptotic process BIRC5;RARG GO:0008284| positive regulation of cell proliferation BIRC5;RARG GO:0006355| regulation of transcription, DNA-dependent BIRC5;RARG 128:[DB02466 DB01222] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 129:[DB02466 DB01403] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;RARG;HTR2A;ADRA2A;CHRM1;ADRA1D GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RARG;DRD2 GO:0010628| positive regulation of gene expression RARG;DRD1 130:[DB02466 DB14009] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0043066| negative regulation of apoptotic process CAT;PTGS2;GPX1;HMGCR;SOD1;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043065| positive regulation of apoptotic process IDO1;SMPD1;SOD1;CNR1;RARG;PTGS2;PPARG;CYP1B1;TRPV1 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HMGCR;CHRNA7;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARG;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;RARG GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;RARG GO:0032526| response to retinoic acid PPARG;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 131:[DB02466 DB11635] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;SEC14L2 GO:0071300| cellular response to retinoic acid RARG;ABCA1 GO:0006351| transcription, DNA-dependent RARG;SEC14L2 132:[DB02466 DB00837] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00837|Progabide GABBR1;GABRA1 common genes common pathways 133:[DB02466 DB13620] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways 134:[DB02466 DB00381] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;CACNA1C;RARG GO:0043065| positive regulation of apoptotic process SMPD1;RARG 135:[DB02466 DB01173] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 136:[DB02466 DB00915] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0008284| positive regulation of cell proliferation CHRNA7;RARG GO:0008285| negative regulation of cell proliferation DRD2;RARG 137:[DB02466 DB00238] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process RARG;ALB 138:[DB02466 DB00214] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways 139:[DB02466 DB00423] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00423|Methocarbamol CA1 common genes common pathways 140:[DB02466 DB06726] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 141:[DB02466 DB00244] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2;RARG GO:0032526| response to retinoic acid RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RARG GO:0043066| negative regulation of apoptotic process RARG;IKBKB;MPO;PTGS2 GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CHUK;RARG;IKBKB GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;RARG GO:0043065| positive regulation of apoptotic process RARG;PPARG;PTGS2 142:[DB02466 DB11274] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD3;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;RARG 143:[DB02466 DB00274] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 144:[DB02466 DB01352] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 145:[DB02466 DB14185] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0010628| positive regulation of gene expression DRD1;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 GO:0008284| positive regulation of cell proliferation RARG;HTR2A;DRD3;HTR1A;ADRA2A;CHRM1 146:[DB02466 DB00759] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;PADI4 GO:0006355| regulation of transcription, DNA-dependent RARG;PADI4 GO:0043066| negative regulation of apoptotic process PRNP;RARG;ALB 147:[DB02466 DB01206] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways 148:[DB02466 DB12001] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0043065| positive regulation of apoptotic process CDK4;RARG GO:0008284| positive regulation of cell proliferation RARG;CDK4 GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0045596| negative regulation of cell differentiation RARG;CDK6 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;CDK4 GO:0010468| regulation of gene expression CDK6;RARG;CDK4 GO:0008285| negative regulation of cell proliferation RARG;CDK6 149:[DB02466 DB01131] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways 150:[DB02466 DB00421] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0006351| transcription, DNA-dependent AR;PGR;NR3C2;NR1I2;NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway AR;PGR;NR3C2;RARG;NR3C1;NR1I2 GO:0008285| negative regulation of cell proliferation AR;RARG GO:0010468| regulation of gene expression AR;RARG GO:0048608| reproductive structure development AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG;NR1I2;NR3C2;PGR;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;NR3C1;RARG GO:0035264| multicellular organism growth RARG;AR GO:0043010| camera-type eye development CACNA1C;RARG GO:0010628| positive regulation of gene expression AR;NR1I2;RARG GO:0060348| bone development RARG;SRD5A2;SRD5A1 GO:0008284| positive regulation of cell proliferation AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1;NR1I2;AR;PGR GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG;NR3C1;PGR;NR3C2;AR GO:0060740| prostate gland epithelium morphogenesis RARG;AR 151:[DB02466 DB00415] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0043066| negative regulation of apoptotic process TEK;ALB;RARG 152:[DB02466 DB00312] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0043065| positive regulation of apoptotic process GRIN2A;RARG;GRIN1 GO:0008284| positive regulation of cell proliferation CHRNA7;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NR1I2;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG 153:[DB02466 DB09183] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways 154:[DB02466 DB01030] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes common pathways 155:[DB02466 DB01466] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 GO:0043066| negative regulation of apoptotic process POR;RARG 156:[DB02466 DB00568] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0010628| positive regulation of gene expression DRD1;RARG GO:0043010| camera-type eye development CACNA1C;RARG;CYP1A1 157:[DB02466 DB01085] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 158:[DB02466 DB00227] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC2;RARG GO:0006351| transcription, DNA-dependent RARG;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;HDAC2 GO:0008284| positive regulation of cell proliferation HMGCR;RARG;HDAC2 GO:0006355| regulation of transcription, DNA-dependent HDAC2;RARG GO:0043066| negative regulation of apoptotic process HMGCR;RARG;HDAC2 GO:0071300| cellular response to retinoic acid RARG;HDAC2 159:[DB02466 DB00883] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways 160:[DB02466 DB01033] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0060041| retina development in camera-type eye RARG;IMPDH2 161:[DB02466 DB06372] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways GO:0008285| negative regulation of cell proliferation IL1A;RARG;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1A;RARG;IL1B GO:0008284| positive regulation of cell proliferation IL1B;RARG GO:0010628| positive regulation of gene expression RARG;IL1B;IL1A 162:[DB02466 DB08814] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0006351| transcription, DNA-dependent RARG;NFKB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NFKB1 GO:0043066| negative regulation of apoptotic process ALB;RARG;NFKB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NFKB1 GO:0006355| regulation of transcription, DNA-dependent RARG;NFKB1 163:[DB02466 DB11619] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0048608| reproductive structure development AR;RARG GO:0010468| regulation of gene expression RARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1;AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1;PGR;NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C1;PGR;AR;ESR1 GO:0008285| negative regulation of cell proliferation RARG;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;PGR;RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;PGR;RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG;ESR1;AR;PGR GO:0008284| positive regulation of cell proliferation AR;RARG GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0035264| multicellular organism growth RARG;AR GO:0010628| positive regulation of gene expression AR;RARG 164:[DB02466 DB09272] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 165:[DB02466 DB00294] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR1;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PGR;ESR1;RARG GO:0006351| transcription, DNA-dependent ESR1;PGR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;ESR1;RARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PGR;RARG 166:[DB02466 DB00657] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 167:[DB02466 DB01182] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 168:[DB02466 DB00810] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 169:[DB02466 DB01018] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;RARG 170:[DB02466 DB05361] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;F2R GO:0008285| negative regulation of cell proliferation F2R;RARG 171:[DB02466 DB01409] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 172:[DB02466 DB00812] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043065| positive regulation of apoptotic process PTGS2;RARG 173:[DB02466 DB00865] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0008284| positive regulation of cell proliferation RARG;ADRA2A GO:0043066| negative regulation of apoptotic process POR;RARG 174:[DB02466 DB13941] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways 175:[DB02466 DB00764] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway PGR;RARG;NR3C1 GO:0006351| transcription, DNA-dependent PGR;RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RARG;NR3C1 176:[DB02466 DB00694] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process POR;RARG GO:0043065| positive regulation of apoptotic process CYP1B1;TOP2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;RARG GO:0008285| negative regulation of cell proliferation RARG;CYP1B1 177:[DB02466 DB00189] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways 178:[DB02466 DB01366] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01366|Procaterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 179:[DB02466 DB08874] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways 180:[DB02466 DB13036] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13036|Ramatroban PTGDR2 common genes common pathways 181:[DB02466 DB01144] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 182:[DB02466 DB01623] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0010628| positive regulation of gene expression DRD1;RARG GO:0008284| positive regulation of cell proliferation HTR2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 183:[DB02466 DB00857] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 184:[DB02466 DB13997] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways 185:[DB02466 DB00691] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways 186:[DB02466 DB09060] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways 187:[DB02466 DB00949] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;GRIN2A 188:[DB02466 DB08912] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0008285| negative regulation of cell proliferation RAF1;RARG GO:0043066| negative regulation of apoptotic process RARG;RAF1;BRAF GO:0010628| positive regulation of gene expression BRAF;RARG GO:0060324| face development BRAF;RARG;RAF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;RARG 189:[DB02466 DB00347] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways 190:[DB02466 DB11755] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;CNR1 GO:0008284| positive regulation of cell proliferation RARG;HTR1A 191:[DB02466 DB00378] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PGR GO:0006351| transcription, DNA-dependent RARG;PGR GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PGR 192:[DB02466 DB08918] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0010628| positive regulation of gene expression SLC6A4;RARG 193:[DB02466 DB03066] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 194:[DB02466 DB01170] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways 195:[DB02466 DB00029] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PLG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;SERPINE1 GO:0043066| negative regulation of apoptotic process PLAUR;RARG 196:[DB02466 DB01129] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 197:[DB02466 DB06589] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;RARG GO:0008284| positive regulation of cell proliferation PDGFRB;FLT1;FGF1;RARG;KIT;FGFR3;KDR;PDGFRA;FLT4 GO:0043065| positive regulation of apoptotic process RARG;PDGFRB GO:0043066| negative regulation of apoptotic process FLT4;RARG;KDR;PDGFRB GO:0010628| positive regulation of gene expression KIT;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0032526| response to retinoic acid PDGFRB;RARG GO:0060349| bone morphogenesis RARG;FGFR3 198:[DB02466 DB00698] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process POR;RARG 199:[DB02466 DB01261] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;RARG 200:[DB02466 DB01108] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR1;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1;RARG GO:0006351| transcription, DNA-dependent RARG;ESR1;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR2;ESR1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;RARG 201:[DB02466 DB04861] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 202:[DB02466 DB06733] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 203:[DB02466 DB02056] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;AKR1C3 204:[DB02466 DB01294] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 205:[DB02466 DB04821] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;MPO GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid SLC6A4;RARG 206:[DB02466 DB00193] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG;CHRNA7 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0008285| negative regulation of cell proliferation RARG;OPRM1 207:[DB02466 DB01022] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 208:[DB02466 DB00611] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 209:[DB02466 DB00726] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00726|Trimipramine SLC6A4;SLC6A2;SLC6A3;HTR2A;HTR1A;ADRA1A;ADRA1B;DRD2;ADRA2B;HRH1;HTR2C;HTR3A;HTR1D;ADRA2A;DRD1;DRD5;ADRB1;ADRB2;ADRB3;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0010628| positive regulation of gene expression SLC6A4;RARG;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;ADRB2 GO:0008284| positive regulation of cell proliferation HTR2A;RARG;HTR1A;CHRM1;ADRA2A GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG 210:[DB02466 DB00745] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 211:[DB02466 DB06770] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 212:[DB02466 DB01234] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1;NR0B1;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG;NR3C1 GO:0043065| positive regulation of apoptotic process CYP1B1;ANXA1;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0045596| negative regulation of cell differentiation NR0B1;RARG GO:0043066| negative regulation of apoptotic process ANXA1;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR0B1;RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;NR0B1;RARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;RARG;NR0B1;NR1I2 GO:0008285| negative regulation of cell proliferation CYP1B1;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;NR0B1;RARG;NR3C1 213:[DB02466 DB01016] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;ABCA1 GO:0043066| negative regulation of apoptotic process ALB;RARG 214:[DB02466 DB05928] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I2 215:[DB02466 DB13952] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0048384| retinoic acid receptor signaling pathway RARG;ESRRG GO:0006351| transcription, DNA-dependent NCOA2;ESRRG;RARG;NR1I2;ESR2;ESR1 GO:0008285| negative regulation of cell proliferation RARG;GPER1;CYP1B1;BECN1 GO:0043401| steroid hormone mediated signaling pathway GPER1;ESR1;ESR2;NR1I2;RARG;ESRRG GO:0032526| response to retinoic acid HSD17B2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NCOA2;ESR2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1;RARG;NR1I2;ESRRG GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process BECN1;RARG;ALB GO:0010628| positive regulation of gene expression NR1I2;RARG;GPER1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;ESRRG;NCOA2;NR1I2;RARG GO:0008284| positive regulation of cell proliferation GPER1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GPER1;ESR1;ESR2;RARG;NR1I2;NCOA2;ESRRG GO:0043065| positive regulation of apoptotic process RARG;GPER1;CYP1B1 216:[DB02466 DB06704] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06704|Iobenguane SLC6A2 common genes common pathways 217:[DB02466 DB00439] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;HMGCR GO:0043066| negative regulation of apoptotic process HMGCR;RARG 218:[DB02466 DB00593] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways 219:[DB02466 DB00508] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRM1;HTR2B GO:0008285| negative regulation of cell proliferation RARG;BCHE;DRD2 220:[DB02466 DB00486] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;RARG 221:[DB02466 DB05120] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05120|AT1391 INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;INSR GO:0008284| positive regulation of cell proliferation INSR;RARG 222:[DB02466 DB00198] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways 223:[DB02466 DB00188] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 224:[DB02466 DB08871] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0043066| negative regulation of apoptotic process BCL2;RARG GO:0008284| positive regulation of cell proliferation BCL2;RARG GO:0008285| negative regulation of cell proliferation BCL2;RARG GO:0010468| regulation of gene expression RARG;BCL2 225:[DB02466 DB00304] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;ESR1;PGR GO:0043401| steroid hormone mediated signaling pathway ESR1;PGR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PGR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ESR1;PGR GO:0006355| regulation of transcription, DNA-dependent RARG;ESR1;PGR 226:[DB02466 DB09223] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD3;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;RARG;HTR2A GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation RARG;DRD2 227:[DB02466 DB09285] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0008285| negative regulation of cell proliferation RARG;PTGS2 228:[DB02466 DB01174] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01174|Phenobarbital GABRA1;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP2C19;CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2;CYP2A6;CYP2E1;CYP3A5;CYP4A11;CYP1A1;CYP1B1;CYP2C18;CYP3A7;CYP4B1;UGT1A1;UGT2B7;ABCB1;ABCC3;ABCB11;ABCC1;SLCO2A1;ABCC2 common genes common pathways GO:0043065| positive regulation of apoptotic process GRIN1;CYP1B1;GRIN2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2;GRIN1 GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0043010| camera-type eye development CYP1A1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2 GO:0008285| negative regulation of cell proliferation CYP1B1;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG 229:[DB02466 DB11251] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0006351| transcription, DNA-dependent SEC14L2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VLDLR;RARG GO:0010628| positive regulation of gene expression RARG;LDLR GO:0006355| regulation of transcription, DNA-dependent RARG;SEC14L2 230:[DB02466 DB00973] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways 231:[DB02466 DB01577] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;ADRA2A GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 232:[DB02466 DB09330] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;RARG GO:0008284| positive regulation of cell proliferation RARG;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;EGFR GO:0010468| regulation of gene expression CYP1A2;RARG 233:[DB02466 DB05740] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 234:[DB02466 DB06616] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 common genes common pathways GO:0001843| neural tube closure RARG;ABL1 GO:0008285| negative regulation of cell proliferation LYN;RARG;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARG GO:0043066| negative regulation of apoptotic process HCK;RARG;SRC GO:0071300| cellular response to retinoic acid RARG;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;RARG GO:0060324| face development RARG;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent RARG;ABL1 GO:0008284| positive regulation of cell proliferation RARG;LYN;CDK2;HCK GO:0043065| positive regulation of apoptotic process RARG;ABL1;SRC 235:[DB02466 DB00473] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 236:[DB02466 DB00441] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0060041| retina development in camera-type eye RARG;RRM1 237:[DB02466 DB00540] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0008284| positive regulation of cell proliferation HTR2A;RARG;HTR1A;ADRA1D;ADRA2A;CHRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;ADRB2;RARG 238:[DB02466 DB05015] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC7;HDAC1;RARG;HDAC9;HDAC3;HDAC4;HDAC2;HDAC8;HDAC10;HDAC5 GO:0006351| transcription, DNA-dependent HDAC1;HDAC7;RARG;HDAC11;HDAC3;HDAC9;HDAC2;HDAC8;HDAC4;HDAC10;HDAC5;HDAC6 GO:0008285| negative regulation of cell proliferation HDAC4;HDAC1;RARG GO:0006355| regulation of transcription, DNA-dependent HDAC6;HDAC5;HDAC10;HDAC2;HDAC8;HDAC4;HDAC11;HDAC3;HDAC9;RARG;HDAC7;HDAC1 GO:0008284| positive regulation of cell proliferation HDAC2;HDAC4;HDAC1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;HDAC1;HDAC3;HDAC4;HDAC2;HDAC5 GO:0043066| negative regulation of apoptotic process HDAC2;RARG;HDAC1;HDAC3 GO:0071300| cellular response to retinoic acid HDAC2;RARG 239:[DB02466 DB01396] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 240:[DB02466 DB00404] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways 241:[DB02466 DB01407] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;NGF GO:0043010| camera-type eye development CYP1A1;RARG GO:0010628| positive regulation of gene expression NGF;TNF;RARG GO:0043068| positive regulation of programmed cell death TNF;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNF;ADRB2 GO:0043065| positive regulation of apoptotic process NGF;RARG;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TNF 242:[DB02466 DB01439] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 243:[DB02466 DB00072] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;RARG GO:0008284| positive regulation of cell proliferation RARG;EGFR GO:0006355| regulation of transcription, DNA-dependent RARG;ERBB2 GO:0043066| negative regulation of apoptotic process RARG;EGFR GO:0010628| positive regulation of gene expression ERBB2;RARG GO:0006351| transcription, DNA-dependent ERBB2;RARG 244:[DB02466 DB00959] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG 245:[DB02466 DB01411] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0006351| transcription, DNA-dependent NFKB1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;RARG;TNF GO:0010628| positive regulation of gene expression RARG;TNF GO:0043066| negative regulation of apoptotic process NFKB1;RARG GO:0043065| positive regulation of apoptotic process RARG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNF;NFKB1 GO:0008284| positive regulation of cell proliferation RARG;IL5 GO:0043068| positive regulation of programmed cell death TNF;RARG GO:0006355| regulation of transcription, DNA-dependent NFKB1;RARG 246:[DB02466 DB00041] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0043066| negative regulation of apoptotic process RARG;IL2RB;PTGS2 247:[DB02466 DB09555] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways 248:[DB02466 DB00379] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;RARG GO:0006355| regulation of transcription, DNA-dependent AHR;RARG GO:0010468| regulation of gene expression AHR;RARG;CYP1A2 GO:0006351| transcription, DNA-dependent RARG;AHR 249:[DB02466 DB09418] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 250:[DB02466 DB00526] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;SOD1;RARG;MPO;NQO1 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043065| positive regulation of apoptotic process CYP1B1;SOD1;RARG GO:0008285| negative regulation of cell proliferation RARG;CYP1B1 GO:0010468| regulation of gene expression ATP7A;RARG 251:[DB02466 DB01127] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2 GO:0006351| transcription, DNA-dependent RARG;NR1I2 252:[DB02466 DB00195] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 253:[DB02466 DB09288] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043065| positive regulation of apoptotic process TRPV1;PTGS2;RARG;CNR1 GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TRPV1 GO:0008285| negative regulation of cell proliferation BCHE;PTGS2;RARG 254:[DB02466 DB01363] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG GO:0008284| positive regulation of cell proliferation RARG;ADRA2A 255:[DB02466 DB14540] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0043065| positive regulation of apoptotic process ANXA1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0043066| negative regulation of apoptotic process ANXA1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RARG GO:0006351| transcription, DNA-dependent NR3C1;RARG 256:[DB02466 DB13953] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2;ESRRG;RARG;NR1I2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RARG;ESR1;ESR2 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0032526| response to retinoic acid HSD17B2;RARG GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;GPER1;ESRRG;NR1I2;RARG GO:0008285| negative regulation of cell proliferation GPER1;CYP1B1;BECN1;RARG GO:0006351| transcription, DNA-dependent ESRRG;NCOA2;NR1I2;RARG;ESR1;ESR2 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RARG GO:0043065| positive regulation of apoptotic process GPER1;CYP1B1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG;ESRRG;NCOA2;GPER1;ESR2;ESR1 GO:0008284| positive regulation of cell proliferation RARG;GPER1 GO:0006355| regulation of transcription, DNA-dependent ESRRG;NCOA2;NR1I2;RARG;ESR1;ESR2 GO:0010628| positive regulation of gene expression RARG;NR1I2;GPER1 GO:0043066| negative regulation of apoptotic process ALB;RARG;BECN1 GO:0043010| camera-type eye development RARG;CYP1A1 257:[DB02466 DB09291] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways 258:[DB02466 DB01351] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 259:[DB02466 DB00435] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043065| positive regulation of apoptotic process IDO1;RARG 260:[DB02466 DB06652] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways 261:[DB02466 DB06412] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;AR GO:0010468| regulation of gene expression RARG;AR GO:0048608| reproductive structure development RARG;AR GO:0043401| steroid hormone mediated signaling pathway RARG;AR GO:0008285| negative regulation of cell proliferation RARG;AR GO:0006351| transcription, DNA-dependent RARG;AR GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0008284| positive regulation of cell proliferation RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;RARG GO:0010628| positive regulation of gene expression RARG;AR GO:0060348| bone development SRD5A1;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0035264| multicellular organism growth AR;RARG 262:[DB02466 DB00604] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;RARG 263:[DB02466 DB08901] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0035264| multicellular organism growth FGFR2;RARG GO:0043066| negative regulation of apoptotic process RARG;KDR;TEK;SRC GO:0071300| cellular response to retinoic acid RARG;LYN;RET;FGFR2 GO:0060348| bone development RARG;FGFR2 GO:0010628| positive regulation of gene expression SRC;RET;KIT;FGFR4;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;FGFR1;ABL1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;RARG GO:0008284| positive regulation of cell proliferation FGFR2;FGFR1;PDGFRA;FLT3;KIT;FGFR4;RARG;LYN;FGFR3;KDR GO:0043065| positive regulation of apoptotic process RARG;ABL1;SRC GO:0001843| neural tube closure RARG;ABL1 GO:0060349| bone morphogenesis RARG;FGFR3;FGFR2 GO:0006351| transcription, DNA-dependent FGFR1;RARG GO:0008285| negative regulation of cell proliferation LYN;RARG GO:0060041| retina development in camera-type eye RET;RARG GO:0048608| reproductive structure development FGFR2;RARG GO:0010468| regulation of gene expression RARG;FGFR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;FGFR1;FGFR2 264:[DB02466 DB11581] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;BCL2 GO:0043066| negative regulation of apoptotic process BCL2;RARG GO:0010468| regulation of gene expression RARG;BCL2 GO:0008285| negative regulation of cell proliferation RARG;BCL2 265:[DB02466 DB01138] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0006351| transcription, DNA-dependent RARG;NR1I2 266:[DB02466 DB06713] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0035264| multicellular organism growth RARG;AR GO:0010628| positive regulation of gene expression RARG;AR GO:0008284| positive regulation of cell proliferation RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;AR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;PGR;AR GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0006351| transcription, DNA-dependent RARG;AR;PGR GO:0043401| steroid hormone mediated signaling pathway RARG;PGR;AR GO:0008285| negative regulation of cell proliferation RARG;AR GO:0010468| regulation of gene expression AR;RARG GO:0048608| reproductive structure development RARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;PGR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RARG 267:[DB02466 DB00637] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways 268:[DB02466 DB01252] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0032526| response to retinoic acid RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RARG GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RARG GO:0008285| negative regulation of cell proliferation RARG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RARG GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG 269:[DB02466 DB00814] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0008285| negative regulation of cell proliferation PTGS2;RARG 270:[DB02466 DB01254] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0008285| negative regulation of cell proliferation CSK;LYN;RARG;FRK;CYP1B1 GO:0043401| steroid hormone mediated signaling pathway NR4A3;RARG GO:0001843| neural tube closure RARG;ABL1 GO:0006351| transcription, DNA-dependent HSPA8;MAPK14;NR4A3;RARG;BTK;STAT5B GO:0000122| negative regulation of transcription from RNA polymerase II promoter FRK;RARG;NR4A3 GO:0006367| transcription initiation from RNA polymerase II promoter NR4A3;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0032526| response to retinoic acid RARG;PDGFRB GO:0071300| cellular response to retinoic acid YES1;ABL2;RARG;LYN GO:0010628| positive regulation of gene expression RARG;KIT;SRC;MAPK14 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043066| negative regulation of apoptotic process SRC;PDGFRB;STAT5B;NR4A3;RARG GO:0043065| positive regulation of apoptotic process RARG;SRC;ABL1;PDGFRB;CYP1B1 GO:0006355| regulation of transcription, DNA-dependent STAT5B;BTK;NR4A3;RARG;MAPK14;ABL1;HSPA8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MAPK14;YES1;STAT5B;RARG;NR4A3 GO:0008284| positive regulation of cell proliferation STAT5B;LYN;KIT;RARG;PDGFRB 271:[DB02466 DB01059] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A GO:0043065| positive regulation of apoptotic process RARG;TOP2A 272:[DB02466 DB05303] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNF GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0010628| positive regulation of gene expression TNF;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;RARG 273:[DB02466 DB00338] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent AHR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;AHR GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression RARG;AHR;CYP1A2 GO:0006351| transcription, DNA-dependent RARG;AHR GO:0008285| negative regulation of cell proliferation CYP1B1;RARG 274:[DB02466 DB09146] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09146|Iron saccharate HBA1;TF common genes common pathways 275:[DB02466 DB00533] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 276:[DB02466 DB00083] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;RHOB 277:[DB02466 DB06772] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 278:[DB02466 DB01395] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;PGR;NR3C2;AR GO:0043401| steroid hormone mediated signaling pathway RARG;AR;PGR;NR3C2 GO:0008285| negative regulation of cell proliferation RARG;BCHE;PTGS2;AR GO:0010468| regulation of gene expression RARG;AR GO:0048608| reproductive structure development AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;AR;NR3C2;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RARG GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0035264| multicellular organism growth AR;RARG GO:0010628| positive regulation of gene expression RARG;AR GO:0008284| positive regulation of cell proliferation RARG;PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;AR;PGR GO:0006355| regulation of transcription, DNA-dependent AR;NR3C2;PGR;RARG GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0043065| positive regulation of apoptotic process RARG;PTGS2 279:[DB02466 DB01126] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0060348| bone development SRD5A1;RARG;SRD5A2 280:[DB02466 DB06370] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways 281:[DB02466 DB09389] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0060348| bone development RARG;SRD5A1 GO:0010628| positive regulation of gene expression RARG;AR GO:0035264| multicellular organism growth RARG;AR GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0006355| regulation of transcription, DNA-dependent RARG;AR;PGR GO:0008284| positive regulation of cell proliferation RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PGR;AR GO:0008285| negative regulation of cell proliferation AR;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;AR;PGR GO:0006351| transcription, DNA-dependent RARG;AR;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter AR;PGR;RARG GO:0048608| reproductive structure development AR;RARG GO:0010468| regulation of gene expression AR;RARG 282:[DB02466 DB08807] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0008284| positive regulation of cell proliferation HTR1A;RARG 283:[DB02466 DB11130] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG 284:[DB02466 DB06734] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 285:[DB02466 DB00589] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;HTR1A;HTR2B;DRD3;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RARG GO:0010628| positive regulation of gene expression DRD1;RARG GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2 286:[DB02466 DB01200] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0008284| positive regulation of cell proliferation ADRA2A;HTR2B;HTR1A;ADRA1D;DRD3;HTR2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 287:[DB02466 DB01240] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0045596| negative regulation of cell differentiation RARG;P2RY12 288:[DB02466 DB05039] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 289:[DB02466 DB04825] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0010628| positive regulation of gene expression RARG;MYLK2 290:[DB02466 DB09029] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09029|Secukinumab IL17A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL17A;RARG 291:[DB02466 DB00836] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0006351| transcription, DNA-dependent NR1I3;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I3 GO:0008285| negative regulation of cell proliferation RARG;OPRM1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;POMC;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I3 292:[DB02466 DB12332] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PARP1 GO:0006355| regulation of transcription, DNA-dependent RARG;PARP1 GO:0006351| transcription, DNA-dependent RARG;PARP1 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PARP1 293:[DB02466 DB14635] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RARG;VDR GO:0006355| regulation of transcription, DNA-dependent VDR;RARG;PPARG GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0043066| negative regulation of apoptotic process RARG;GSTP1 GO:0010628| positive regulation of gene expression RARG;VDR GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0032526| response to retinoic acid RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RARG;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;RARG;PPARG GO:0006351| transcription, DNA-dependent PPARG;VDR;RARG GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR;RARG GO:0008285| negative regulation of cell proliferation PPARG;RARG;VDR 294:[DB02466 DB00877] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0031641| regulation of myelination MTOR;RARG GO:0008284| positive regulation of cell proliferation RARG;FGF2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;RARG GO:0008361| regulation of cell size RARG;MTOR GO:0010628| positive regulation of gene expression MTOR;RARG GO:0035264| multicellular organism growth MTOR;RARG 295:[DB02466 DB11712] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 296:[DB02466 DB06212] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways GO:0010628| positive regulation of gene expression RARG;AVPR2 GO:0008284| positive regulation of cell proliferation AVPR1A;AVPR2;RARG 297:[DB02466 DB05668] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05668|Palifosfamide DNMT1 common genes common pathways GO:0010468| regulation of gene expression DNMT1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;RARG GO:0006351| transcription, DNA-dependent DNMT1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;DNMT1 GO:0010628| positive regulation of gene expression RARG;DNMT1 298:[DB02466 DB01102] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 299:[DB02466 DB00655] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0048608| reproductive structure development RARG;AR GO:0010468| regulation of gene expression CYP1A2;AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1;AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;AR;ESR1;ESR2 GO:0006351| transcription, DNA-dependent AR;ESR1;ESR2;RARG GO:0008285| negative regulation of cell proliferation CYP1B1;AR;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;AR;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;AR;ESR1;ESR2 GO:0008284| positive regulation of cell proliferation RARG;AR GO:0043065| positive regulation of apoptotic process RARG;CYP1B1 GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0043010| camera-type eye development CYP1A1;RARG GO:0035264| multicellular organism growth RARG;AR GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010628| positive regulation of gene expression RARG;AR 300:[DB02466 DB00696] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0008284| positive regulation of cell proliferation HTR1A;HTR2B;ADRA1D;ADRA2A;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 301:[DB02466 DB05087] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways 302:[DB02466 DB04840] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 303:[DB02466 DB01219] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways 304:[DB02466 DB00845] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways 305:[DB02466 DB09065] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09065|Cobicistat CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 306:[DB02466 DB09166] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways 307:[DB02466 DB00782] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00782|Propantheline CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 308:[DB02466 DB14508] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0043066| negative regulation of apoptotic process GSK3B;RARG GO:0060070| canonical Wnt receptor signaling pathway RARG;GSK3B GO:0010628| positive regulation of gene expression RARG;GSK3B 309:[DB02466 DB00502] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00502|Haloperidol DRD2;DRD1;GRIN2B;HTR2A;DRD3;MCHR1;SLC18A2;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP3A4;CBR1;UGT1A9;CYP1A1;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0010628| positive regulation of gene expression DRD1;RARG GO:0008284| positive regulation of cell proliferation DRD3;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD3;DRD2 310:[DB02466 DB00503] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00503|Ritonavir pol;NR1I2;CYP2D6;CYP2C9;CYP2C19;CYP2B6;CYP2C8;CYP1A2;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;UGT1A1;ALB;ABCB1;ABCC1;SLCO1A2;ABCC2;ABCG2;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2 GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG 311:[DB02466 DB08838] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;GRIN1 GO:0043065| positive regulation of apoptotic process RARG;GRIN1 312:[DB02466 DB00131] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0035264| multicellular organism growth PDE4D;RARG GO:0043066| negative regulation of apoptotic process RARG;PIM1;PRKAA1 GO:0008361| regulation of cell size CREB1;RARG GO:0010628| positive regulation of gene expression RARG;PRKAB1;PRKAA1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HINT1;PRKAA1;RARG GO:1990830| RARG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;RARG GO:0008284| positive regulation of cell proliferation PRKAA1;RARG GO:0043065| positive regulation of apoptotic process CREB1;RARG GO:0006351| transcription, DNA-dependent RARG;CREB1;HINT1;PRKAA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;FBP1 313:[DB02466 DB00594] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;RARG GO:0043065| positive regulation of apoptotic process SLC9A1;RARG GO:0043066| negative regulation of apoptotic process SLC9A1;ASIC2;RARG 314:[DB02466 DB06288] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RARG;DRD2 315:[DB02466 DB09282] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 316:[DB02466 DB00630] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways 317:[DB02466 DB00237] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 318:[DB02466 DB09053] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0006351| transcription, DNA-dependent BTK;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0006355| regulation of transcription, DNA-dependent BTK;RARG 319:[DB02466 DB00276] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;RARG GO:0043065| positive regulation of apoptotic process TOP2A;RARG 320:[DB02466 DB00458] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00458|Imipramine SLC6A2;HTR2A;SLC6A4;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCND2;KCND3;HTR2C;ADRA1B;HTR7;DRD1;DRD5;DRD2;KCNH2;SLC6A3;HTR1A;HTR6;KCNH1;ORM2;CYP2C19;CYP2D6;CYP1A2;CYP3A4;CYP3A7;CYP2B6;CYP2C18;CYP2E1;ORM1;ALB;ABCB1;SLC22A2;SLC22A3;SLC22A4 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression DRD1;RARG;SLC6A4 GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0008284| positive regulation of cell proliferation CHRM1;ADRA1D;HTR1A;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 321:[DB02466 DB00346] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0008284| positive regulation of cell proliferation ADRA1D;RARG 322:[DB02466 DB00675] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESRRG;RARG;NR1I2;AR;ESR1;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR1;ESR2;AR GO:0010468| regulation of gene expression RARG;AR GO:0048608| reproductive structure development RARG;AR GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2;ESRRG;AR;ESR1;ESR2 GO:0008285| negative regulation of cell proliferation RARG;CYP1B1;AR GO:0006351| transcription, DNA-dependent AR;PRKCB;ESR1;ESR2;RARG;NR1I2;ESRRG GO:0048384| retinoic acid receptor signaling pathway RARG;ESRRG GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;NR1I2;RARG;ESR1;ESR2;AR GO:0008284| positive regulation of cell proliferation AR;PRKCZ;RARG GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;AR;PRKCB;ESRRG;PRKCQ;NR1I2;RARG GO:0010628| positive regulation of gene expression AR;NR1I2;RARG GO:0043066| negative regulation of apoptotic process PRKCI;PRKCZ;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0045637| regulation of myeloid cell differentiation RARG;PRKCB GO:0035264| multicellular organism growth AR;RARG 323:[DB02466 DB14065] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways 324:[DB02466 DB01496] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 325:[DB02466 DB11637] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 326:[DB02466 DB06148] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0010628| positive regulation of gene expression SLC6A4;DRD1;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RARG;DRD2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2B;ADRA1D;ADRA2A;HTR2A;RARG;DRD3 327:[DB02466 DB00315] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR1A 328:[DB02466 DB07720] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 329:[DB02466 DB03566] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 330:[DB02466 DB01074] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways 331:[DB02466 DB05091] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05091|M0002 AVPR2 common genes common pathways GO:0010628| positive regulation of gene expression RARG;AVPR2 GO:0008284| positive regulation of cell proliferation AVPR2;RARG 332:[DB02466 DB06595] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0043066| negative regulation of apoptotic process PDGFRB;RARG;KDR GO:0010628| positive regulation of gene expression KIT;RARG GO:0008284| positive regulation of cell proliferation PDGFRB;RARG;KIT;KDR;PDGFRA;FLT3 GO:0043065| positive regulation of apoptotic process RARG;PDGFRB GO:0032526| response to retinoic acid RARG;PDGFRB GO:0010468| regulation of gene expression CYP1A2;RARG 333:[DB02466 DB00790] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0060349| bone morphogenesis RARG;SFRP4 GO:0008285| negative regulation of cell proliferation BCHE;RARG;SFRP4 GO:0043065| positive regulation of apoptotic process SFRP4;RARG GO:0010628| positive regulation of gene expression SFRP4;RARG 334:[DB02466 DB01296] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;NFKB2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;NFKB2;RARG;TNF GO:0043066| negative regulation of apoptotic process RARG;MMP9 GO:0010628| positive regulation of gene expression IFNG;RARG;TNF GO:0006355| regulation of transcription, DNA-dependent RARG;NFKB2 GO:0008284| positive regulation of cell proliferation RARG;IFNG GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB2;RARG;TNF GO:0043065| positive regulation of apoptotic process MMP9;RARG;TNF 335:[DB02466 DB00849] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2 GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG 336:[DB02466 DB01412] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ADORA1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;RARG GO:0008285| negative regulation of cell proliferation RARG;ADORA2A;ADORA1 GO:0010468| regulation of gene expression RARG;CYP1A2 337:[DB02466 DB04827] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0043066| negative regulation of apoptotic process MPO;RARG 338:[DB02466 DB00549] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 339:[DB02466 DB00531] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2 340:[DB02466 DB06700] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG 341:[DB02466 DB00852] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0010468| regulation of gene expression ATF5;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TNF;JDP2;ATF3;ATF2;ATF7 GO:0006351| transcription, DNA-dependent ATF7;ATF5;ATF1;ATF6;NFATC1;ATF4;JDP2;RARG;JUN;ATF3;ATF2 GO:0008285| negative regulation of cell proliferation JUN;RARG;ATF5;ADRA1A GO:0006355| regulation of transcription, DNA-dependent ATF2;ATF3;JUN;RARG;FOS;JDP2;ATF4;NFATC1;ATF6;ATF1;ATF5;ATF7 GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0008284| positive regulation of cell proliferation RARG;JUN;IL2;ATF3;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ATF5;ATF6;NFATC1;ATF1;ADRB2;ATF4;RARG;JUN;FOS;TNF;IL2;ATF2;ATF3 GO:0043065| positive regulation of apoptotic process RARG;JUN;TNF;ATF4;ATF6 GO:0035264| multicellular organism growth ATF5;RARG GO:0043066| negative regulation of apoptotic process ATF5;JUN;RARG;IL2 GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG;TNF;ATF4;ATF3;ATF2 342:[DB02466 DB01588] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways 343:[DB02466 DB00396] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0035264| multicellular organism growth RARG;AR GO:0010628| positive regulation of gene expression NR1I2;RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG;NR1I2;PGR;AR;ESR1 GO:0008284| positive regulation of cell proliferation AR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1;NR1I2;AR;ESR1;PGR;NR3C2 GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG;NR3C1;PGR;NR3C2;ESR1;AR GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG;NR3C1;PGR;NR3C2;ESR1;AR GO:0008285| negative regulation of cell proliferation RARG;AR;CYP1B1 GO:0010468| regulation of gene expression AR;RARG GO:0048608| reproductive structure development AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR;NR3C2;PGR;NR1I2;NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR;RARG;NR3C1 344:[DB02466 DB00289] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;RARG GO:0043065| positive regulation of apoptotic process GRIN1;RARG;GRIN2A 345:[DB02466 DB00946] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00946|Phenprocoumon VKORC1;CYP2C8;CYP2C9;CYP3A4;ALB;ORM1 common genes common pathways GO:0060348| bone development RARG;VKORC1 GO:0043066| negative regulation of apoptotic process ALB;RARG 346:[DB02466 DB06751] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0043010| camera-type eye development CACNA1C;RARG 347:[DB02466 DB05521] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 348:[DB02466 DB01288] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 349:[DB02466 DB08827] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways 350:[DB02466 DB06155] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;RARG 351:[DB02466 DB06274] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 352:[DB02466 DB11431] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways 353:[DB02466 DB06292] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043010| camera-type eye development CYP1A1;RARG 354:[DB02466 DB00715] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0008284| positive regulation of cell proliferation CHRM1;RARG;HTR2A GO:0010468| regulation of gene expression CYP1A2;RARG 355:[DB02466 DB00567] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 356:[DB02466 DB01483] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 357:[DB02466 DB00834] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1;NR1I2;PGR GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1;NR1I2;PGR GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RARG;NR3C1;NR1I2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006351| transcription, DNA-dependent NR1I2;RARG;NR3C1;PGR GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1;NR1I2;PGR 358:[DB02466 DB00978] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A GO:0043065| positive regulation of apoptotic process RARG;TOP2A GO:0010468| regulation of gene expression RARG;CYP1A2 359:[DB02466 DB06603] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC9;HDAC3;HDAC7;HDAC1;RARG;HDAC5;HDAC4;HDAC8;HDAC2;HDAC10 GO:0006351| transcription, DNA-dependent HDAC9;HDAC3;HDAC11;RARG;HDAC7;HDAC1;HDAC6;HDAC5;HDAC10;HDAC4;HDAC2;HDAC8 GO:0008285| negative regulation of cell proliferation HDAC4;RARG;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;HDAC1;HDAC3;HDAC4;HDAC2;HDAC5 GO:0008284| positive regulation of cell proliferation HDAC4;HDAC2;HDAC1;RARG GO:0006355| regulation of transcription, DNA-dependent HDAC1;HDAC7;RARG;HDAC3;HDAC11;HDAC9;HDAC2;HDAC8;HDAC4;HDAC10;HDAC5;HDAC6 GO:0043066| negative regulation of apoptotic process HDAC3;HDAC1;RARG;HDAC2 GO:0071300| cellular response to retinoic acid RARG;HDAC2 360:[DB02466 DB09030] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;F2R GO:0008284| positive regulation of cell proliferation F2R;RARG 361:[DB02466 DB00537] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;RARG 362:[DB02466 DB00305] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00305|Mitomycin POR common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;POR 363:[DB02466 DB00501] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00501|Cimetidine HRH2;CYP1A2;CYP2C19;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP11B1;CYP2C8;CYP2C9;CYP2E1;FMO3;FMO1;ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A6;SLC22A8;SLC47A1;SLC22A4;SLC22A11;SLC22A7;ABCB11;SLC47A2 common genes common pathways GO:0048732| gland development HRH2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 364:[DB02466 DB00619] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;PDGFRB;ABL1 GO:0008284| positive regulation of cell proliferation PDGFRB;KIT;RARG;CSF1R;PDGFRA GO:0043068| positive regulation of programmed cell death NTRK1;RARG GO:0006355| regulation of transcription, DNA-dependent ABL1;RARG GO:0010628| positive regulation of gene expression RET;RARG;KIT GO:0071300| cellular response to retinoic acid RARG;RET GO:0043066| negative regulation of apoptotic process NTRK1;CSF1R;ALB;RARG;PDGFRB GO:0032526| response to retinoic acid RARG;PDGFRB GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0060041| retina development in camera-type eye RET;RARG GO:0008285| negative regulation of cell proliferation NTRK1;CSF1R;DDR1;RARG GO:0001843| neural tube closure RARG;ABL1 365:[DB02466 DB01263] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways 366:[DB02466 DB08882] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;DPP4 367:[DB02466 DB00182] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;ADRB2;RARG GO:0008284| positive regulation of cell proliferation RARG;ADRA2A;ADRA1D 368:[DB02466 DB00921] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 369:[DB02466 DB01590] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0031641| regulation of myelination RARG;MTOR GO:0008361| regulation of cell size RARG;MTOR GO:0010628| positive regulation of gene expression RARG;MTOR GO:0035264| multicellular organism growth MTOR;RARG 370:[DB02466 DB00661] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0008284| positive regulation of cell proliferation RARG;ADRA1D GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0010468| regulation of gene expression RARG;CYP1A2 371:[DB02466 DB01307] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;INSR GO:0008284| positive regulation of cell proliferation RARG;INSR GO:0043066| negative regulation of apoptotic process RARG;ALB 372:[DB02466 DB01571] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 373:[DB02466 DB00353] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;HTR2B GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0010628| positive regulation of gene expression RARG;DRD1 374:[DB02466 DB08820] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 375:[DB02466 DB00324] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 376:[DB02466 DB04938] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;RARG 377:[DB02466 DB13961] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0010628| positive regulation of gene expression RARG;PPARD GO:0043010| camera-type eye development RARG;CACNA1C GO:0043066| negative regulation of apoptotic process FFAR4;NFKB1;RARG;PPARD;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PPARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;SREBF1;PPARA;RARG;PPARD;NFKB2;NFKB1 GO:0008284| positive regulation of cell proliferation RARG;PPARD;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NFKB2;NFKB1;PPARG;PPARA;SREBF1 GO:0008285| negative regulation of cell proliferation RARG;PTGS2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG;PPARD;RARG GO:0006351| transcription, DNA-dependent NFKB2;NFKB1;RARG;PPARD;SREBF1;PPARA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB2;NFKB1;RARG;PPARD;PPARA;SREBF1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;RARG;PPARG;PPARA GO:0032526| response to retinoic acid RARG;PPARG;SREBF1 GO:0010468| regulation of gene expression PPARA;RARG 378:[DB02466 DB00261] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;PDE3A GO:0010468| regulation of gene expression RARG;CYP1A2 379:[DB02466 DB00444] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A 380:[DB02466 DB01098] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process HMGCR;ALB;RARG GO:0008284| positive regulation of cell proliferation RARG;HMGCR 381:[DB02466 DB01236] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 382:[DB02466 DB09481] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;RARG GO:0043065| positive regulation of apoptotic process RARG;GRIN2A;GRIN1 383:[DB02466 DB13954] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0048384| retinoic acid receptor signaling pathway RARG;ESRRG GO:0006351| transcription, DNA-dependent NR1I2;RARG;ESRRG;NCOA2;ESR1;ESR2 GO:0008285| negative regulation of cell proliferation RARG;BECN1;CYP1B1;GPER1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;GPER1;ESRRG;RARG;NR1I2 GO:0032526| response to retinoic acid RARG;HSD17B2 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NCOA2;ESR1;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2;ESRRG;RARG;NR1I2 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043066| negative regulation of apoptotic process BECN1;RARG;ALB GO:0010628| positive regulation of gene expression RARG;NR1I2;GPER1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG;ESRRG;NCOA2;ESR2;ESR1 GO:0008284| positive regulation of cell proliferation RARG;GPER1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG;ESRRG;NCOA2;GPER1;ESR2;ESR1 GO:0043065| positive regulation of apoptotic process RARG;GPER1;CYP1B1 384:[DB02466 DB00075] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CD3D;RARG GO:0010628| positive regulation of gene expression CD3E;RARG 385:[DB02466 DB09063] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways 386:[DB02466 DB00514] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0008361| regulation of cell size RAC1;RARG GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0008284| positive regulation of cell proliferation RAC2;RARG;CHRNA7 GO:0043065| positive regulation of apoptotic process RAC1;RARG GO:0008285| negative regulation of cell proliferation RARG;OPRM1 387:[DB02466 DB01275] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways 388:[DB02466 DB01327] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB;IL2 GO:0008284| positive regulation of cell proliferation IL2;IL15;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;RARG 389:[DB02466 DB00342] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 390:[DB02466 DB00398] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process PDGFRB;BRAF;FLT4;KDR;RAF1;RARG GO:0010628| positive regulation of gene expression KIT;RARG;BRAF;RET GO:0071300| cellular response to retinoic acid RARG;RET GO:0008284| positive regulation of cell proliferation KDR;RARG;KIT;FLT4;FLT3;FGFR1;FLT1;PDGFRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;RAF1 GO:0060324| face development BRAF;RAF1;RARG GO:0006355| regulation of transcription, DNA-dependent FGFR1;RARG GO:0043065| positive regulation of apoptotic process PDGFRB;RARG GO:0006351| transcription, DNA-dependent RARG;FGFR1 GO:0060041| retina development in camera-type eye RARG;RET GO:0008285| negative regulation of cell proliferation RAF1;RARG GO:0032526| response to retinoic acid PDGFRB;RARG GO:0010468| regulation of gene expression FGFR1;CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;FGFR1 391:[DB02466 DB09034] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways 392:[DB02466 DB01242] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01242|Clomipramine SLC6A4;HTR2A;HTR2B;HTR2C;SLC6A2;GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;ALB;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008284| positive regulation of cell proliferation RARG;HTR2A;HTR2B GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0043066| negative regulation of apoptotic process RARG;ALB;GSTP1;HTR2B 393:[DB02466 DB00470] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;RARG GO:0043010| camera-type eye development RARG;CYP1A1 394:[DB02466 DB00559] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;EDNRB GO:0043066| negative regulation of apoptotic process RARG;EDNRB GO:0008284| positive regulation of cell proliferation EDNRB;RARG 395:[DB02466 DB00823] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR1;PGR GO:0043401| steroid hormone mediated signaling pathway ESR1;PGR;RARG GO:0006351| transcription, DNA-dependent ESR1;PGR;RARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PGR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PGR;RARG 396:[DB02466 DB01154] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways 397:[DB02466 DB01356] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;GSK3B GO:0010628| positive regulation of gene expression RARG;GSK3B GO:0060070| canonical Wnt receptor signaling pathway GSK3B;RARG 398:[DB02466 DB06779] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;RARG GO:0010628| positive regulation of gene expression RARG;VEGFA GO:0043066| negative regulation of apoptotic process RARG;VEGFA GO:0008284| positive regulation of cell proliferation VEGFA;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;RARG 399:[DB02466 DB06702] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 400:[DB02466 DB00351] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG;PGR GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway PGR;NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C1;PGR 401:[DB02466 DB11672] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;RARG GO:0010628| positive regulation of gene expression VDR;RARG GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;VDR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RARG;VDR GO:0043065| positive regulation of apoptotic process RARG;PPARG GO:0006351| transcription, DNA-dependent PPARG;RARG;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;RARG;PPARG GO:0008285| negative regulation of cell proliferation PPARG;VDR;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0032526| response to retinoic acid PPARG;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;VDR;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;VDR;RARG 402:[DB02466 DB00668] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0010628| positive regulation of gene expression RARG;TNF GO:0043065| positive regulation of apoptotic process TNF;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNF;RARG GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0008284| positive regulation of cell proliferation RARG;ADRA1D;ADRA2A GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;RARG 403:[DB02466 DB09295] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 404:[DB02466 DB00328] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;PPARG;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PPARA;RARG GO:0008284| positive regulation of cell proliferation AKR1C3;RARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB;GLO1;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARA;PPARG GO:0010468| regulation of gene expression PPARA;RARG GO:0032526| response to retinoic acid RARG;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA;RARG GO:0008285| negative regulation of cell proliferation RARG;PTGS2;PPARG GO:0006351| transcription, DNA-dependent PPARG;PPARA;RARG 405:[DB02466 DB00394] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG 406:[DB02466 DB00286] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RARG 407:[DB02466 DB00811] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0060041| retina development in camera-type eye IMPDH2;RARG 408:[DB02466 DB00577] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways 409:[DB02466 DB01149] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR2A;ADRA2A;HTR1A GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG 410:[DB02466 DB11582] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:1990830| TNFSF11;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNFSF11 411:[DB02466 DB00202] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE GO:0008284| positive regulation of cell proliferation CHRM1;RARG;CHRNA7 412:[DB02466 DB06697] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways 413:[DB02466 DB01095] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process HMGCR;RARG GO:0008284| positive regulation of cell proliferation RARG;HMGCR 414:[DB02466 DB14063] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways 415:[DB02466 DB04953] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways 416:[DB02466 DB00320] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2B;ADRA2A;RARG GO:0043066| negative regulation of apoptotic process RARG;HTR2B 417:[DB02466 DB00368] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;POU5F1 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0010468| regulation of gene expression RARG;POU5F1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter POU5F1;RARG GO:0006355| regulation of transcription, DNA-dependent POU5F1;RARG GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter POU5F1;ADRB2;RARG 418:[DB02466 DB00074] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0043066| negative regulation of apoptotic process IL2RB;RARG 419:[DB02466 DB00755] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes RARG common pathways GO:0043065| positive regulation of apoptotic process RARB;RARG;ALDH1A2 GO:0060173| limb development RARG;RARA GO:0002068| glandular epithelial cell development RARB;RARA;RARG GO:0048732| gland development RARG GO:0060740| prostate gland epithelium morphogenesis RARG GO:0009952| anterior/posterior pattern specification CYP26C1;RARG;ALDH1A2 GO:0048048| embryonic eye morphogenesis RARG;RARB GO:1990830| RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;RXRB;RARG;RARB;RXRA;RXRG GO:0008284| positive regulation of cell proliferation RARA;RARG;RARB;ALDH1A2 GO:0043068| positive regulation of programmed cell death RARB;RARG GO:0032331| negative regulation of chondrocyte differentiation RARB;RARG GO:0060324| face development RARG;RARA;ALDH1A2 GO:0006355| regulation of transcription, DNA-dependent CRABP2;RXRG;RARB;RXRA;RARA;RXRB;NR0B1;RARG GO:0010628| positive regulation of gene expression RARG;CYP26B1;RARA;ALDH1A2 GO:0008361| regulation of cell size RARG GO:0071300| cellular response to retinoic acid ALDH1A2;RARA;CYP26B1;RARG GO:0060348| bone development RARG;RARA;RARB GO:0060070| canonical Wnt receptor signaling pathway RARG GO:0043066| negative regulation of apoptotic process RARB;RARG;ALB;RARA GO:0045596| negative regulation of cell differentiation RARG;NR0B1;RARA GO:0043010| camera-type eye development RARG;RXRA;CYP1A1;ALDH1A2 GO:0045637| regulation of myeloid cell differentiation RARG GO:0003417| growth plate cartilage development RARG;RARA;RARB GO:0035264| multicellular organism growth RARB;RARA;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;RARB;RARG;NR0B1;RARA;RXRB;RXRG GO:0003430| growth plate cartilage chondrocyte growth RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;RARA;NR0B1;RXRA;RARB GO:0031076| embryonic camera-type eye development RARG;RARA;ALDH1A2 GO:0010468| regulation of gene expression RARG GO:0061037| negative regulation of cartilage development RARB;RARA;RARG GO:0032526| response to retinoic acid RBP4;RARA;RARG;RXRA GO:0070384| Harderian gland development RARG GO:0060534| trachea cartilage development RARA;RARG GO:0035116| embryonic hindlimb morphogenesis RARG;RARB GO:0048608| reproductive structure development RARG GO:0060041| retina development in camera-type eye RARB;RARG GO:0060429| epithelium development RARG GO:0043401| steroid hormone mediated signaling pathway RARB;RXRA;RARG;RXRB;RARA;NR0B1;RXRG GO:0008285| negative regulation of cell proliferation ALDH1A2;RARRES1;RARA;RARG;RARB GO:0006351| transcription, DNA-dependent RXRG;RARA;RXRB;NR0B1;RARG;RXRA;RARB GO:0002063| chondrocyte development RARG GO:0031641| regulation of myelination RARB;RARG;RARA GO:0003406| retinal pigment epithelium development RARG;RARB GO:0001843| neural tube closure RARA;RARG GO:0048384| retinoic acid receptor signaling pathway RXRG;ALDH1A2;RXRB;RARA;CYP26B1;RARG;RXRA;RARB GO:0060349| bone morphogenesis RARG;CYP26B1 420:[DB02466 DB03128] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0060041| retina development in camera-type eye ACHE;RARG GO:0008284| positive regulation of cell proliferation CHRNA7;RARG;CHRM1 421:[DB02466 DB01306] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01306|Insulin Aspart INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;INSR GO:0008284| positive regulation of cell proliferation INSR;RARG 422:[DB02466 DB05773] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ERBB2;RARG GO:0010628| positive regulation of gene expression ERBB2;RARG GO:0006351| transcription, DNA-dependent RARG;ERBB2 423:[DB02466 DB01614] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2;ADRA1A GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0008284| positive regulation of cell proliferation HTR1A;RARG;HTR2A 424:[DB02466 DB13151] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0010468| regulation of gene expression F2;RARG GO:0008284| positive regulation of cell proliferation F2;RARG 425:[DB02466 DB00475] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways 426:[DB02466 DB01431] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PGR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;PGR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;ESR1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PGR;ESR1 GO:0006351| transcription, DNA-dependent RARG;ESR1;PGR 427:[DB02466 DB01382] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways 428:[DB02466 DB08836] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways 429:[DB02466 DB00714] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD3;DRD2 GO:0008284| positive regulation of cell proliferation RARG;HTR2A;DRD3;HTR2B;HTR1A;ADRA2A GO:0010628| positive regulation of gene expression DRD1;RARG GO:0043066| negative regulation of apoptotic process HTR2B;RARG 430:[DB02466 DB09099] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:1990830| RARG;SSTR1 GO:0008285| negative regulation of cell proliferation SSTR5;SSTR1;SSTR4;SSTR3;RARG;SSTR2 431:[DB02466 DB00176] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;RARG 432:[DB02466 DB06822] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0008284| positive regulation of cell proliferation CXCL12;RARG 433:[DB02466 DB00200] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways 434:[DB02466 DB09564] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09564|Insulin Degludec INSR common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;INSR GO:0006355| regulation of transcription, DNA-dependent RARG;INSR 435:[DB02466 DB14517] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;RARG GO:0043065| positive regulation of apoptotic process RARG;APP GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010628| positive regulation of gene expression APP;RARG GO:0010468| regulation of gene expression RARG;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;APP GO:0008285| negative regulation of cell proliferation RARG;APP 436:[DB02466 DB01212] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 437:[DB02466 DB00762] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE GO:0043066| negative regulation of apoptotic process ALB;RARG 438:[DB02466 DB00243] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways 439:[DB02466 DB00884] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 440:[DB02466 DB01056] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB 441:[DB02466 DB00555] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0043066| negative regulation of apoptotic process RARG;ADORA1 GO:0008284| positive regulation of cell proliferation CHRM1;ADRA2A;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0006355| regulation of transcription, DNA-dependent ADORA2A;RARG GO:0008285| negative regulation of cell proliferation ADORA1;DRD2;ADRA1A;ADORA2A;RARG 442:[DB02466 DB04896] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;GRIN1 GO:0043065| positive regulation of apoptotic process GRIN2A;RARG;GRIN1 GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0071300| cellular response to retinoic acid SLC6A4;RARG 443:[DB02466 DB01354] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 444:[DB02466 DB01255] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways 445:[DB02466 DB01202] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways 446:[DB02466 DB00344] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 447:[DB02466 DB00007] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways 448:[DB02466 DB00455] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways 449:[DB02466 DB13874] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 450:[DB02466 DB01136] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;ADRA1D;ADRA2A;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;ADRB2;RARG;HIF1A GO:0006355| regulation of transcription, DNA-dependent HIF1A;RARG GO:0043066| negative regulation of apoptotic process RARG;HIF1A;VEGFA GO:0043010| camera-type eye development RARG;CYP1A1 GO:0010628| positive regulation of gene expression HIF1A;RARG;GJA1;VEGFA GO:0032526| response to retinoic acid RARG;GJA1 GO:0010468| regulation of gene expression CYP1A2;HIF1A;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;RARG GO:0006351| transcription, DNA-dependent RARG;HIF1A GO:0008285| negative regulation of cell proliferation GJA1;ADRA1A;RARG 451:[DB02466 DB01621] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010628| positive regulation of gene expression DRD1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2 452:[DB02466 DB00425] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 453:[DB02466 DB11278] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0008284| positive regulation of cell proliferation ADRA2A;ADRA1D;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 454:[DB02466 DB11979] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways 455:[DB02466 DB07776] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESRRB;ESRRA;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRB;ESRRA;RARG GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;ESRRB;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESRRB;ESRRA GO:0006351| transcription, DNA-dependent ESRRA;ESRRB;RARG GO:0008285| negative regulation of cell proliferation CYP1B1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;ESRRB;ESRRA 456:[DB02466 DB00962] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0043065| positive regulation of apoptotic process TSPO;RARG 457:[DB02466 DB01026] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent AR;RARG;NR1I3;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;RARG;NR1I2;NR1I3 GO:0008284| positive regulation of cell proliferation AR;RARG GO:0043065| positive regulation of apoptotic process RARG;CYP1B1 GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0035264| multicellular organism growth RARG;AR GO:0010628| positive regulation of gene expression AR;RARG;NR1I2 GO:0048608| reproductive structure development RARG;AR GO:0010468| regulation of gene expression CYP1A2;AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;NR1I3;RARG;AR GO:0006351| transcription, DNA-dependent AR;RARG;NR1I2;NR1I3 GO:0008285| negative regulation of cell proliferation AR;CYP1B1;RARG GO:0043401| steroid hormone mediated signaling pathway AR;NR1I3;NR1I2;RARG 458:[DB02466 DB01203] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 459:[DB02466 DB01048] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways 460:[DB02466 DB11090] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 461:[DB02466 DB01097] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;AHR GO:0008285| negative regulation of cell proliferation PTK2B;RARG GO:0010468| regulation of gene expression CYP1A2;AHR;RARG GO:0043066| negative regulation of apoptotic process PTK2B;RARG GO:0071300| cellular response to retinoic acid PTK2B;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;RARG GO:0008284| positive regulation of cell proliferation PTK2B;RARG GO:0006355| regulation of transcription, DNA-dependent AHR;RARG GO:0043065| positive regulation of apoptotic process DHODH;RARG 462:[DB02466 DB00670] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00670|Pirenzepine CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 463:[DB02466 DB01169] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation PML;CYP1B1;HDAC1;JUN;RARG;CDKN1A GO:0048384| retinoic acid receptor signaling pathway RARG;PML GO:0031641| regulation of myelination AKT1;RARG GO:0006351| transcription, DNA-dependent JUN;RARG;HDAC1;CCND1;MAPK1;PML;MAPK3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;HDAC1;CCND1 GO:0006367| transcription initiation from RNA polymerase II promoter CCND1;CDKN1A;RARG GO:0060070| canonical Wnt receptor signaling pathway RARG;CCND1 GO:0010628| positive regulation of gene expression MAPK3;MAPK1;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0045596| negative regulation of cell differentiation RARG;MAPK1 GO:0043066| negative regulation of apoptotic process AKT1;ALB;JUN;RARG;HDAC1;CDKN1A;IKBKB GO:0043065| positive regulation of apoptotic process AKT1;RARG;JUN;CYP1B1 GO:0060324| face development RARG;MAPK3;MAPK1 GO:0006355| regulation of transcription, DNA-dependent PML;MAPK1;CCND1;HDAC1;RARG;JUN GO:0008284| positive regulation of cell proliferation MAPK1;CCND1;HDAC1;RARG;AKT1;JUN GO:0043068| positive regulation of programmed cell death CDKN1A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;JUN;AKT1;RARG;IKBKB;PML;MAPK3 GO:1990830| PML;RARG 464:[DB02466 DB00831] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 465:[DB02466 DB09225] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0010628| positive regulation of gene expression SLC6A4;DRD1;RARG GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation HTR2A;RARG 466:[DB02466 DB09237] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0043010| camera-type eye development CACNA1C;RARG GO:0008285| negative regulation of cell proliferation RARG;NOS3 467:[DB02466 DB00570] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0006351| transcription, DNA-dependent JUN;RARG GO:0008285| negative regulation of cell proliferation JUN;RARG GO:0008284| positive regulation of cell proliferation JUN;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;JUN GO:0006355| regulation of transcription, DNA-dependent JUN;RARG GO:0043065| positive regulation of apoptotic process RARG;JUN GO:0043066| negative regulation of apoptotic process JUN;RARG 468:[DB02466 DB04348] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR1H4 GO:0006367| transcription initiation from RNA polymerase II promoter NR1H4;RARG GO:0006351| transcription, DNA-dependent RARG;NR1H4 GO:0008285| negative regulation of cell proliferation FABP6;RARG GO:0043401| steroid hormone mediated signaling pathway NR1H4;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;RARG GO:0043066| negative regulation of apoptotic process NR1H4;RARG 469:[DB02466 DB00463] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 470:[DB02466 DB00579] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0010628| positive regulation of gene expression SLC6A4;RARG 471:[DB02466 DB04895] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04895|Pegaptanib NRP1 common genes common pathways 472:[DB02466 DB00678] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 473:[DB02466 DB14538] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process ANXA1;RARG GO:0043065| positive regulation of apoptotic process RARG;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 474:[DB02466 DB01384] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 475:[DB02466 DB06712] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C 476:[DB02466 DB00401] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C 477:[DB02466 DB01054] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways GO:0043010| camera-type eye development CACNA1C;RARG 478:[DB02466 DB01274] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 479:[DB02466 DB00669] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;RARG 480:[DB02466 DB01151] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0043065| positive regulation of apoptotic process SMPD1;RARG GO:0008284| positive regulation of cell proliferation HTR1A;ADRA1D;ADRA2A;CHRM1;HTR2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG;DRD2 481:[DB02466 DB06636] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways 482:[DB02466 DB00081] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 483:[DB02466 DB00490] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0008284| positive regulation of cell proliferation HTR1A;RARG 484:[DB02466 DB01043] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0043065| positive regulation of apoptotic process GRIN1;GRIN2A;RARG GO:0008284| positive regulation of cell proliferation CHRNA7;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;GRIN1;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2 485:[DB02466 DB00968] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;ADRA2A 486:[DB02466 DB01107] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways 487:[DB02466 DB01076] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0006351| transcription, DNA-dependent AHR;RARG GO:0010468| regulation of gene expression RARG;AHR GO:0043066| negative regulation of apoptotic process HMGCR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;AHR GO:0008284| positive regulation of cell proliferation RARG;HMGCR;DPP4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;AHR 488:[DB02466 DB09073] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter CDK4;RARG GO:0010468| regulation of gene expression CDK6;RARG;CDK4 GO:0008285| negative regulation of cell proliferation CDK6;RARG GO:0043065| positive regulation of apoptotic process RARG;CDK4 GO:0008284| positive regulation of cell proliferation CDK4;RARG GO:0045596| negative regulation of cell differentiation CDK6;RARG 489:[DB02466 DB08816] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0045596| negative regulation of cell differentiation P2RY12;RARG 490:[DB02466 DB01418] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01418|Acenocoumarol VKORC1;CYP2C9;CYP1A2;CYP2C19;CYP3A4;ALB;ORM1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0060348| bone development RARG;VKORC1 491:[DB02466 DB00356] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043065| positive regulation of apoptotic process RARG;KCNMA1 492:[DB02466 DB09039] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways 493:[DB02466 DB01332] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways 494:[DB02466 DB06016] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RARG GO:0008284| positive regulation of cell proliferation DRD3;HTR2A;RARG;HTR2B;HTR1A GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation DRD2;RARG 495:[DB02466 DB00322] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0031641| regulation of myelination RARG;TYMP 496:[DB02466 DB01216] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0060348| bone development RARG;SRD5A2;SRD5A1 497:[DB02466 DB00371] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways 498:[DB02466 DB06684] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;RARG GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 499:[DB02466 DB00530] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0008284| positive regulation of cell proliferation RARG;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG;EGFR GO:0043065| positive regulation of apoptotic process RARG;CYP1B1 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043066| negative regulation of apoptotic process ALB;RARG;EGFR GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I2 GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0008285| negative regulation of cell proliferation CYP1B1;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG 500:[DB02466 DB00903] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0043066| negative regulation of apoptotic process LEF1;RARG;ALB;GSTP1 GO:0010628| positive regulation of gene expression RARG;LEF1 GO:0060070| canonical Wnt receptor signaling pathway RARG;LEF1 GO:0008284| positive regulation of cell proliferation LEF1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;LEF1 GO:0006355| regulation of transcription, DNA-dependent RARG;LEF1 GO:0006351| transcription, DNA-dependent RARG;LEF1 GO:0043401| steroid hormone mediated signaling pathway LEF1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter LEF1;RARG 501:[DB02466 DB01223] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;HDAC2 GO:0006351| transcription, DNA-dependent HDAC2;RARG GO:0008285| negative regulation of cell proliferation RARG;ADORA3;ADORA1 GO:0008284| positive regulation of cell proliferation RARG;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;HDAC2 GO:0006355| regulation of transcription, DNA-dependent HDAC2;RARG GO:0043066| negative regulation of apoptotic process RARG;PDE3A;ADORA1;HDAC2 GO:0071300| cellular response to retinoic acid RARG;HDAC2 502:[DB02466 DB00108] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:1990830| RARG;ICAM1 503:[DB02466 DB09236] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways GO:0043010| camera-type eye development CACNA1C;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG 504:[DB02466 DB08930] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes common pathways 505:[DB02466 DB04905] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG 506:[DB02466 DB00682] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00682|Warfarin VKORC1;NR1I2;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2C8;CYP2C18;CYP1A1;ALB;ORM1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2 GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0060348| bone development VKORC1;RARG GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG 507:[DB02466 DB11397] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE GO:0043066| negative regulation of apoptotic process RARG;ALB 508:[DB02466 DB01589] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways 509:[DB02466 DB00104] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation SSTR2;RARG;SSTR1;SSTR5 GO:0043066| negative regulation of apoptotic process MPO;RARG GO:1990830| SSTR1;RARG 510:[DB02466 DB06414] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06414|Etravirine CYP3A4;CYP2C9;CYP2C19;ABCB1;ABCB4 common genes common pathways 511:[DB02466 DB00633] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0008284| positive regulation of cell proliferation ADRA2A;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 512:[DB02466 DB01587] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;TSPO GO:0043066| negative regulation of apoptotic process ALB;RARG 513:[DB02466 DB09154] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 514:[DB02466 DB01583] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;THRA;RARG GO:0006355| regulation of transcription, DNA-dependent THRB;THRA;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0006367| transcription initiation from RNA polymerase II promoter THRB;THRA;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;THRB GO:0043401| steroid hormone mediated signaling pathway THRA;THRB;RARG GO:0006351| transcription, DNA-dependent THRA;THRB;RARG 515:[DB02466 DB00331] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0010628| positive regulation of gene expression RARG;PRKAB1 516:[DB02466 DB09230] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways 517:[DB02466 DB01264] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01264|Darunavir pol;CYP3A4;SLCO1B1;ABCB1 common genes common pathways 518:[DB02466 DB00850] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0010628| positive regulation of gene expression DRD1;RARG 519:[DB02466 DB05514] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05514|Cobiprostone CLCN2 common genes common pathways GO:0060041| retina development in camera-type eye RARG;CLCN2 520:[DB02466 DB01559] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways 521:[DB02466 DB04794] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways 522:[DB02466 DB12141] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0008284| positive regulation of cell proliferation FLT3;HTR2A;RARG;HTR2B;HTR1A GO:0043066| negative regulation of apoptotic process HTR2B;RARG;ALB;AXL 523:[DB02466 DB00252] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes common pathways GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG 524:[DB02466 DB00078] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 525:[DB02466 DB04946] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR2A;DRD3;HTR1A GO:0010628| positive regulation of gene expression DRD1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 526:[DB02466 DB14064] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways 527:[DB02466 DB06814] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06814|Protokylol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 528:[DB02466 DB00773] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A GO:0043065| positive regulation of apoptotic process RARG;PTGS2;TOP2A GO:0043066| negative regulation of apoptotic process RARG;GSTP1;PTGS2 529:[DB02466 DB00580] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 530:[DB02466 DB00515] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE;PTGS2 GO:0010468| regulation of gene expression ATP7A;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB;SOD1;GSTP1;PTGS2;NQO1;MPO GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;RARG 531:[DB02466 DB00794] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 532:[DB02466 DB00178] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE 533:[DB02466 DB09227] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0043010| camera-type eye development CACNA1C;RARG 534:[DB02466 DB00925] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;RARG 535:[DB02466 DB12418] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12418|Saccharin CA3 common genes common pathways 536:[DB02466 DB09167] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0008284| positive regulation of cell proliferation HTR2A;RARG;ADRA2A;CHRM1;HTR1A;ADRA1D GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0071300| cellular response to retinoic acid SLC6A4;RARG 537:[DB02466 DB00446] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways 538:[DB02466 DB01973] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 539:[DB02466 DB00373] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 540:[DB02466 DB00393] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter NR3C2;RARG GO:0010468| regulation of gene expression RARG;AHR GO:0043401| steroid hormone mediated signaling pathway NR3C2;RARG GO:0006351| transcription, DNA-dependent RARG;AHR;NR3C2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;RARG GO:0006355| regulation of transcription, DNA-dependent AHR;RARG;NR3C2 GO:0043010| camera-type eye development RARG;CACNA1C 541:[DB02466 DB00825] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C 542:[DB02466 DB01105] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 543:[DB02466 DB00207] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;PADI4 GO:0006351| transcription, DNA-dependent PADI4;RARG 544:[DB02466 DB06290] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010468| regulation of gene expression RARG;CYP1A2 545:[DB02466 DB06287] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0008361| regulation of cell size RARG;MTOR GO:0010628| positive regulation of gene expression MTOR;RARG GO:0035264| multicellular organism growth RARG;MTOR GO:0031641| regulation of myelination MTOR;RARG 546:[DB02466 DB11995] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways 547:[DB02466 DB06457] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06457|Tecastemizole KCNH2 common genes common pathways 548:[DB02466 DB00829] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00829|Diazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9;CYP2B6;CYP2C18;CYP2C8;PTGS1;CYP2E1;ALB;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0043065| positive regulation of apoptotic process RARG;TSPO 549:[DB02466 DB00864] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00864|Tacrolimus FKBP1A;CYP3A7;CYP3A5;CYP3A4;ALB;ORM1;ABCB1;ABCA5;SLCO1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 550:[DB02466 DB00734] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0008284| positive regulation of cell proliferation ADRA2A;HTR1A;DRD3;RARG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 GO:0010628| positive regulation of gene expression RARG;DRD1 551:[DB02466 DB00653] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C 552:[DB02466 DB00573] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0043066| negative regulation of apoptotic process PTGS2;RARG;ALB GO:0043065| positive regulation of apoptotic process PTGS2;PPARG;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARG;PPARA GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0008285| negative regulation of cell proliferation RARG;PPARG;PTGS2 GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG;PPARA GO:0006351| transcription, DNA-dependent RARG;PPARG;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PPARA;RARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA;RARG GO:0010468| regulation of gene expression PPARA;RARG GO:0032526| response to retinoic acid PPARG;RARG 553:[DB02466 DB00788] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG;ALB GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043065| positive regulation of apoptotic process PTGS2;RARG 554:[DB02466 DB01267] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01267|Paliperidone HTR2A;DRD2;HRH1;ADRA1A;ADRA1B;DRD4;HTR1D;DRD3;HTR2C;ADRA2A;ADRA2B;ADRA2C;HTR1A;DRD1;HTR7;CYP3A4;CYP2D6;CYP3A5;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;HTR1A;DRD3;HTR2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation RARG;DRD2;ADRA1A 555:[DB02466 DB00224] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00224|Indinavir pol;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;ABCB1;SLC22A1;ABCC1;SLCO1A2;SLCO1B1;ABCC2;SLCO2B1;ABCB11 common genes common pathways 556:[DB02466 DB00869] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways 557:[DB02466 DB00539] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;RARG GO:0006351| transcription, DNA-dependent RARG;ESR1 558:[DB02466 DB09061] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;CNR1;SOD1;SMPD1;IDO1;PTGS2;TRPV1;CYP1B1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A;HMGCR;CHRNA7;RARG;HTR2A GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0010628| positive regulation of gene expression RARG;TRPV4 GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process HMGCR;RARG;SOD1;PTGS2;CAT;ADORA1;GPX1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TRPV4;PPARG;TRPV1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0032526| response to retinoic acid RARG;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;ADORA1;PPARG;CYP1B1;OPRM1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0006351| transcription, DNA-dependent RARG;PPARG 559:[DB02466 DB00397] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0010628| positive regulation of gene expression RARG;DRD1 560:[DB02466 DB00908] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00908|Quinidine SCN5A;KCNK1;KCNK6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A7;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP2B6;CYP2C9;CYP2C8;ORM1;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A8;ABCC2;SLC22A4;SLCO1B1;ABCB11 common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 GO:0008284| positive regulation of cell proliferation ADRA1D;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0010468| regulation of gene expression CYP1A2;RARG 561:[DB02466 DB05012] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05012|XEN2174 SLC6A2 common genes common pathways 562:[DB02466 DB00728] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways 563:[DB02466 DB00612] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 564:[DB02466 DB00213] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways 565:[DB02466 DB08922] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR2A;ADRA1D;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0043010| camera-type eye development CYP1A1;RARG 566:[DB02466 DB01576] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 567:[DB02466 DB01068] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0043065| positive regulation of apoptotic process TSPO;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010628| positive regulation of gene expression RARG;NR1I2 568:[DB02466 DB03615] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB03615|Ribostamycin P4HB;rpsL common genes common pathways 569:[DB02466 DB11598] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11598|Antithrombin III human SERPINC1 common genes common pathways 570:[DB02466 DB00270] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways GO:0043010| camera-type eye development CACNA1C;RARG 571:[DB02466 DB00999] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways GO:0043065| positive regulation of apoptotic process KCNMA1;RARG 572:[DB02466 DB00741] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0043066| negative regulation of apoptotic process RARG;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0043065| positive regulation of apoptotic process RARG;ANXA1 573:[DB02466 DB08872] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways 574:[DB02466 DB00233] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;CHUK GO:0043066| negative regulation of apoptotic process RARG;PTGS2;MPO GO:0008285| negative regulation of cell proliferation PTGS2;RARG 575:[DB02466 DB05155] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05155|CR665 OPRK1 common genes common pathways 576:[DB02466 DB09080] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 577:[DB02466 DB06654] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043010| camera-type eye development CYP1A1;RARG 578:[DB02466 DB00613] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0008285| negative regulation of cell proliferation CYP1B1;RARG 579:[DB02466 DB14518] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;RARG GO:0010468| regulation of gene expression RARG;APP GO:0008285| negative regulation of cell proliferation RARG;APP GO:0043065| positive regulation of apoptotic process APP;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;APP GO:0010628| positive regulation of gene expression RARG;APP GO:0043066| negative regulation of apoptotic process ALB;RARG 580:[DB02466 DB00220] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00220|Nelfinavir CYP2B6;CYP2C19;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;CYP2C9;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 581:[DB02466 DB00867] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 582:[DB02466 DB00169] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;RARG GO:0006351| transcription, DNA-dependent RARG;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;VDR GO:0006367| transcription initiation from RNA polymerase II promoter RARG;VDR GO:0010628| positive regulation of gene expression VDR;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent VDR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;VDR 583:[DB02466 DB11901] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0048608| reproductive structure development AR;RARG GO:0010468| regulation of gene expression AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;RARG GO:0006351| transcription, DNA-dependent AR;RARG GO:0008285| negative regulation of cell proliferation RARG;AR GO:0043401| steroid hormone mediated signaling pathway AR;RARG GO:0006355| regulation of transcription, DNA-dependent AR;RARG GO:0008284| positive regulation of cell proliferation AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;AR GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0035264| multicellular organism growth AR;RARG GO:0010628| positive regulation of gene expression RARG;AR 584:[DB02466 DB01586] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1H4 GO:0008284| positive regulation of cell proliferation AKR1C2;RARG GO:0043066| negative regulation of apoptotic process NR1H4;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR1H4 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1H4 GO:0006351| transcription, DNA-dependent NR1H4;RARG GO:0043401| steroid hormone mediated signaling pathway NR1H4;RARG 585:[DB02466 DB00880] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways 586:[DB02466 DB11633] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C 587:[DB02466 DB01229] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01229|Paclitaxel TUBB1;BCL2;NR1I2;MAP4;MAP2;MAPT;CYP3A5;CYP3A7;CYP2C8;CYP3A4;CYP19A1;CYP1B1;ABCB11;ABCB1;ABCC1;ABCC10;SLCO1B3;ABCG2;ABCC2 common genes common pathways GO:0010468| regulation of gene expression RARG;BCL2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0008285| negative regulation of cell proliferation CYP1B1;BCL2;RARG GO:0008284| positive regulation of cell proliferation BCL2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0043065| positive regulation of apoptotic process RARG;CYP1B1 GO:0043066| negative regulation of apoptotic process BCL2;RARG GO:0010628| positive regulation of gene expression NR1I2;RARG 588:[DB02466 DB12267] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;INSR;EGFR;ERBB4;FLT3;IGF1R GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;EGFR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;INSR;ERBB4;ERBB2;ABL1 GO:0043065| positive regulation of apoptotic process RARG;ERBB4;ABL1 GO:0043066| negative regulation of apoptotic process IGF1R;RARG;EGFR;ERBB4 GO:0010628| positive regulation of gene expression RARG;ERBB2 GO:0006351| transcription, DNA-dependent ERBB2;ERBB4;RARG GO:0001843| neural tube closure RARG;ABL1 GO:0008285| negative regulation of cell proliferation RARG;ERBB4 589:[DB02466 DB04828] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04828|Zomepirac PTGDR2;CYP3A4;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 590:[DB02466 DB00411] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0060041| retina development in camera-type eye ACHE;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRM1 591:[DB02466 DB00918] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes common pathways 592:[DB02466 DB00957] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PGR;AR;ESR1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;PGR;RARG GO:0008284| positive regulation of cell proliferation RARG;AR GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0035264| multicellular organism growth AR;RARG GO:0010628| positive regulation of gene expression AR;RARG GO:0048608| reproductive structure development AR;RARG GO:0010468| regulation of gene expression RARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1;PGR;RARG GO:0006351| transcription, DNA-dependent PGR;AR;ESR1;RARG GO:0008285| negative regulation of cell proliferation AR;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PGR;AR;ESR1 593:[DB02466 DB04860] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04860|Isatoribine TLR7 common genes common pathways 594:[DB02466 DB00841] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;ESR1 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0008284| positive regulation of cell proliferation ADRA1D;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;RARG 595:[DB02466 DB11817] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0008284| positive regulation of cell proliferation PTK2B;JAK2;RARG GO:0043065| positive regulation of apoptotic process RARG;JAK2 GO:0043066| negative regulation of apoptotic process RARG;PTK2B GO:0071300| cellular response to retinoic acid RARG;PTK2B GO:0008285| negative regulation of cell proliferation RARG;JAK2;PTK2B 596:[DB02466 DB08808] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 597:[DB02466 DB14059] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RELA;NFKB2;NFKB1;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2;RELA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB2;NFKB1;RARG;RELA GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0043066| negative regulation of apoptotic process NFKB1;RARG;PTGS2;RELA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RELA;RARG;NFKB2;NFKB1 GO:0006351| transcription, DNA-dependent RELA;NFKB1;NFKB2;RARG GO:0008285| negative regulation of cell proliferation RARG;PTGS2 598:[DB02466 DB01309] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01309|Insulin Glulisine INSR common genes common pathways GO:0008284| positive regulation of cell proliferation INSR;RARG GO:0006355| regulation of transcription, DNA-dependent INSR;RARG 599:[DB02466 DB00309] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways 600:[DB02466 DB00625] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00625|Efavirenz pol;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP2C8;UGT1A1;ALB;ABCB11;SLC22A1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process RARG;ALB 601:[DB02466 DB00674] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 GO:0008285| negative regulation of cell proliferation BCHE;RARG GO:0060041| retina development in camera-type eye ACHE;RARG 602:[DB02466 DB06153] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0008284| positive regulation of cell proliferation HTR2B;HTR1A;ADRA1D;ADRA2A;CHRM1;HTR2A;RARG 603:[DB02466 DB09129] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09129|Chromic chloride INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent INSR;RARG GO:0008284| positive regulation of cell proliferation RARG;INSR 604:[DB02466 DB00384] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 605:[DB02466 DB08811] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;RARG GO:0043066| negative regulation of apoptotic process PDE3A;RARG 606:[DB02466 DB01077] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 607:[DB02466 DB00942] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00942|Cycrimine CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 608:[DB02466 DB08860] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB;HMGCR GO:0008284| positive regulation of cell proliferation HMGCR;RARG 609:[DB02466 DB12010] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0060041| retina development in camera-type eye RET;MERTK;BMPR1B;RARG;BMPR2;NTRK2 GO:0008285| negative regulation of cell proliferation ADORA3;CSK;NTRK1;ERBB4;TGFBR2;EIF2AK2;LYN;RARG;FRK;PTK2B;RAF1;DDR1;CSF1R;STK3;EIF2AK1;JAK2 GO:0002063| chondrocyte development RARG;BMPR2;BMPR1B GO:0006351| transcription, DNA-dependent MAPK14;DAPK3;PRKAA2;MAP3K9;CHEK2;PKN2;FGFR1;PKN1;ERBB2;MAPK13;TXK;ERBB4;EIF2AK2;PDPK1;RARG;HIPK2;ERN1;HIPK3;PRKAA1;CSNK2A2;CSNK2A1;BTK;MAP2K6 GO:0031641| regulation of myelination MTOR;RARG GO:0001843| neural tube closure RARG;ABL1;PRKACB GO:0060349| bone morphogenesis FGFR3;FGFR2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter CDK4;CDK1;RARG GO:0003430| growth plate cartilage chondrocyte growth RARG;TGFBR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HIPK2;PLK3;AURKB;PLK1;FGFR2;FGFR1;MAP2K5;RARG;FRK GO:0010468| regulation of gene expression MAPK15;CDK1;MAPK4;CDK4;PRKAA2;MAPK10;TGFBR1;MAP3K4;LRRK2;MAPK13;FGFR1;TGFBR2;RARG;ICK GO:0032526| response to retinoic acid PDGFRB;RARG;TIE1;CLK2 GO:0048608| reproductive structure development FGFR2;RARG GO:0010628| positive regulation of gene expression MTOR;GSK3A;MUSK;EPHB2;MYLK2;KIT;CDK1;SRC;RET;PIK3CD;PRKAG1;PRKAA1;BRAF;GSK3B;ACVR1B;NTRK2;RARG;ROCK2;TGFBR1;MAPK14;NTRK3;MAPK9;PRKAB1;ERBB2 GO:0008361| regulation of cell size MTOR;RARG GO:0071300| cellular response to retinoic acid FGFR2;PTK2B;LTK;NTRK3;YES1;RARG;LYN;ABL2;EPHA3;PTK6;RET GO:0060348| bone development RARG;FGFR2 GO:0060070| canonical Wnt receptor signaling pathway LRRK2;RARG;GSK3B GO:0043066| negative regulation of apoptotic process PRKCI;SRC;TEK;AURKA;PRKAA1;BRAF;EGFR;HCK;CSF1R;KDR;MAPK7;TGFBR1;PLK1;PTK2B;PIM3;EIF2AK2;GSK3B;RARG;PLK2;HIPK3;PIM1;RPS6KA1;PLK3;CDK1;RAF1;AXL;RPS6KA3;PRKAA2;PDGFRB;RIPK2;PAK2;LTK;IRAK1;ERBB4;CAMK1D;NTRK1;MAP4K4;FLT4;PTK2;IKBKB;DAPK1;NUAK2 GO:0043010| camera-type eye development BMPR1B;RARG GO:0003417| growth plate cartilage development RARG;TGFBR2 GO:0035264| multicellular organism growth MTOR;RARG;FGFR2 GO:0043065| positive regulation of apoptotic process CAMK1D;ERBB4;EPHA7;RIPK2;PDGFRB;MAPK9;MAP3K9;NTRK3;STK3;LATS1;CDK4;JAK2;RARG;MELK;RIPK1;ABL1;DAPK3;TGFBR1;MAP2K6;MAP3K10;STK17A;MAP3K11;SRC GO:0060173| limb development BMPR2;RARG GO:0009952| anterior/posterior pattern specification BMPR2;HIPK2;RARG;TGFBR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TBK1;MAP2K5;PRKD1;BMPR1B;FGFR2;RIPK1;YES1;CAMK1;MAPK7;EGFR;BMPR2;IKBKB;TXK;ACVR1B;RIPK2;CASK;RPS6KA3;MAPK14;RAF1;RPS6KA1;MET;HIPK2;ACVR1;STK16 GO:0043068| positive regulation of programmed cell death NTRK1;MARK4;LRRK2;RIPK1;RARG GO:0008284| positive regulation of cell proliferation KDR;KIT;CSF1R;MATK;PDGFRA;EGFR;HCK;PRKAA1;TTK;RARG;FGFR2;PTK2B;TGFBR1;MST1R;CDK4;FGFR3;INSR;CSNK2A1;FLT1;HIPK2;JAK2;NTRK2;LYN;FLT4;PTK2;TGFBR2;ERBB4;FLT3;FGFR1;EPHA1;DDR2;FER;NTRK3;PAK1;PDGFRB GO:0060324| face development RAF1;BRAF;RARG GO:0032331| negative regulation of chondrocyte differentiation RARG;TGFBR1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;TXK;ACVR1B;ERBB4;PAK6;FGFR1;MAPK13;PKN1;MAPK14;PKN2;MAP3K9;PRKAA2;INSR;CSNK2A1;CSNK2A2;HIPK3;ERN1;HIPK2;RARG;EIF2AK2;ERBB2;DAPK3;TGFBR1;ABL1;CHEK2;BTK;MAP2K6;PRKCQ;PRKAA1 610:[DB02466 DB00690] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00690|Flurazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP2E1;CYP2A6;CYP3A4;ABCB1;SLC22A2 common genes common pathways 611:[DB02466 DB04846] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 612:[DB02466 DB00896] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 613:[DB02466 DB06789] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PGR GO:0043401| steroid hormone mediated signaling pathway RARG;PGR GO:0006351| transcription, DNA-dependent PGR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RARG 614:[DB02466 DB11827] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 615:[DB02466 DB00584] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes common pathways 616:[DB02466 DB00485] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways 617:[DB02466 DB12070] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways 618:[DB02466 DB00520] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways 619:[DB02466 DB05708] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 620:[DB02466 DB00180] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 621:[DB02466 DB06716] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 622:[DB02466 DB00641] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;HMGCR GO:0043066| negative regulation of apoptotic process HMGCR;RARG 623:[DB02466 DB00259] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways 624:[DB02466 DB00683] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00683|Midazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRB1;GABRB3;GABRB2;GABRA6;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP4B1;UGT1A4;CYP2E1;ABCB1;ABCB11 common genes common pathways 625:[DB02466 DB00306] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 626:[DB02466 DB00279] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0006351| transcription, DNA-dependent THRB;RARG;THRA GO:0043401| steroid hormone mediated signaling pathway THRA;RARG;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;RARG GO:0006367| transcription initiation from RNA polymerase II promoter THRB;RARG;THRA GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0006355| regulation of transcription, DNA-dependent THRB;RARG;THRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;THRB;THRA 627:[DB02466 DB04975] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;RARG GO:0043010| camera-type eye development CYP1A1;RARG 628:[DB02466 DB00818] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00818|Propofol GABRB2;GABRB3;SCN4A;SCN2A;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP2B6;UGT1A8;UGT1A9;UGT1A1;FAAH;CYP2E1;CYP1B1;CYP1A1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;UGT1A6;ALB common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008285| negative regulation of cell proliferation RARG;CYP1B1 GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0043010| camera-type eye development CYP1A1;RARG 629:[DB02466 DB00636] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARA GO:0006355| regulation of transcription, DNA-dependent RARG;PPARA GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression PPARA;RARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARA GO:0006351| transcription, DNA-dependent PPARA;RARG GO:0043401| steroid hormone mediated signaling pathway PPARA;RARG 630:[DB02466 DB05115] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05115|NN344 INSR common genes common pathways GO:0008284| positive regulation of cell proliferation INSR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;INSR 631:[DB02466 DB05849] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05849|NCX 950 ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 632:[DB02466 DB04445] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04445|Mercuric iodide SULT2A1 common genes common pathways 633:[DB02466 DB00751] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;RARG;ADRA2A GO:0048732| gland development RARG;HRH2 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 634:[DB02466 DB00805] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0060041| retina development in camera-type eye ACHE;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation CHRM1;HTR2A;HTR2B;RARG GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression RARG;DRD1;SLC6A4 635:[DB02466 DB00199] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010468| regulation of gene expression RARG;CYP1A2 636:[DB02466 DB00374] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARD;RARG GO:0008284| positive regulation of cell proliferation RARG;PPARD GO:0010628| positive regulation of gene expression PPARD;RARG GO:0045596| negative regulation of cell differentiation P2RY12;RARG GO:0043066| negative regulation of apoptotic process PPARD;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;RARG GO:0043401| steroid hormone mediated signaling pathway PPARD;RARG GO:0006351| transcription, DNA-dependent RARG;PPARD 637:[DB02466 DB08899] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway RARG;AR GO:0008285| negative regulation of cell proliferation AR;RARG GO:0006351| transcription, DNA-dependent RARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RARG GO:0010468| regulation of gene expression RARG;AR GO:0048608| reproductive structure development RARG;AR GO:0010628| positive regulation of gene expression RARG;AR GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0035264| multicellular organism growth RARG;AR GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;RARG GO:0008284| positive regulation of cell proliferation RARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;RARG 638:[DB02466 DB01134] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C2 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C2 GO:0006351| transcription, DNA-dependent NR3C2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C2 639:[DB02466 DB00253] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 640:[DB02466 DB01323] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways 641:[DB02466 DB00939] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG 642:[DB02466 DB01892] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2 643:[DB02466 DB06754] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06754|Danaparoid SERPINC1 common genes common pathways 644:[DB02466 DB13346] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC10;RARG GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0006351| transcription, DNA-dependent RARG;HDAC10;HDAC6 GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0006355| regulation of transcription, DNA-dependent HDAC6;HDAC10;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG 645:[DB02466 DB04920] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways GO:0043010| camera-type eye development RARG;CACNA1C GO:0008285| negative regulation of cell proliferation BCHE;RARG 646:[DB02466 DB06218] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways 647:[DB02466 DB01006] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways 648:[DB02466 DB13931] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0010628| positive regulation of gene expression RARG;ROCK1;ROCK2 649:[DB02466 DB00257] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I3;NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR1I2;NR1I3 GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;NR1I3;RARG GO:0006351| transcription, DNA-dependent RARG;NR1I3;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I3;NR1I2;RARG 650:[DB02466 DB08865] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;RARG 651:[DB02466 DB08813] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MYC;RARG GO:0010468| regulation of gene expression MYC;RARG GO:0006351| transcription, DNA-dependent RARG;MYC GO:0006355| regulation of transcription, DNA-dependent FOS;RARG;MYC GO:0045944| positive regulation of transcription from RNA polymerase II promoter MYC;RARG;FOS GO:0008284| positive regulation of cell proliferation RARG;MYC GO:0060070| canonical Wnt receptor signaling pathway MYC;RARG GO:0010628| positive regulation of gene expression MYC;RARG GO:0043066| negative regulation of apoptotic process RARG;MYC 652:[DB02466 DB09082] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 653:[DB02466 DB00055] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0010468| regulation of gene expression F2;RARG GO:0008284| positive regulation of cell proliferation RARG;F2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PF4;SERPINE1;RARG GO:0010628| positive regulation of gene expression PF4;RARG 654:[DB02466 DB01359] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 655:[DB02466 DB00281] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;RARG GO:0008284| positive regulation of cell proliferation EGFR;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 656:[DB02466 DB00524] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00524|Metolazone SLC12A3 common genes common pathways 657:[DB02466 DB01110] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01110|Miconazole NOS3;NOS2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;KCNH2;KCNH6;KCNH7;NR1I2;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP11B1;CYP51A1;CYP19A1;ABCB1 common genes common pathways GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0043065| positive regulation of apoptotic process KCNMA1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0008285| negative regulation of cell proliferation RARG;NOS3 GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG 658:[DB02466 DB00924] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 659:[DB02466 DB08893] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08893|Mirabegron ADRB3;CYP3A4;CYP2D6;BCHE;ALB;ORM1;ABCB1;SLCO1A2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE GO:0043066| negative regulation of apoptotic process RARG;ALB 660:[DB02466 DB06433] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0060041| retina development in camera-type eye RRM1;RARG GO:0031641| regulation of myelination TYMP;RARG 661:[DB02466 DB09401] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0043066| negative regulation of apoptotic process MCL1;RARG;BCL2L1;BCL2 GO:0043065| positive regulation of apoptotic process BCL2L1;RARG GO:0008284| positive regulation of cell proliferation BCL2;RARG;BCL2L1 GO:0008285| negative regulation of cell proliferation BCL2;RARG GO:0010468| regulation of gene expression RARG;BCL2 662:[DB02466 DB07348] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways 663:[DB02466 DB08810] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;HTR1A;HTR2A 664:[DB02466 DB06154] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;NOS3 665:[DB02466 DB05109] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways 666:[DB02466 DB01437] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways 667:[DB02466 DB06204] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0008285| negative regulation of cell proliferation RARG;OPRM1 668:[DB02466 DB09028] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 669:[DB02466 DB00744] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process RARG;ALB 670:[DB02466 DB06186] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06186|Ipilimumab CTLA4 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;CTLA4 671:[DB02466 DB00247] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2B;RARG;HTR1A;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;RARG 672:[DB02466 DB04977] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways 673:[DB02466 DB06271] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 674:[DB02466 DB00367] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0035264| multicellular organism growth RARG;AR GO:0060348| bone development SRD5A1;RARG GO:0010628| positive regulation of gene expression RARG;AR GO:0006355| regulation of transcription, DNA-dependent PGR;AR;RARG;ESR1 GO:0008284| positive regulation of cell proliferation AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;RARG;PGR;ESR1 GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0006351| transcription, DNA-dependent ESR1;PGR;RARG;AR GO:0008285| negative regulation of cell proliferation AR;RARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PGR;RARG;AR GO:0048608| reproductive structure development RARG;AR GO:0010468| regulation of gene expression RARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PGR;RARG;AR 675:[DB02466 DB13956] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;RARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1I2;ESR2;RARG;ESRRG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0032526| response to retinoic acid HSD17B2;RARG GO:0008285| negative regulation of cell proliferation BECN1;CYP1B1;GPER1;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1;ESRRG;GPER1;RARG;ESR2 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RARG GO:0006351| transcription, DNA-dependent ESR1;NR1I2;NCOA2;ESR2;RARG;ESRRG GO:0043065| positive regulation of apoptotic process GPER1;CYP1B1;RARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;ESR1;NCOA2;RARG;ESR2;ESRRG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR1I2;NCOA2;ESR2;RARG;GPER1;ESRRG GO:0008284| positive regulation of cell proliferation RARG;GPER1 GO:0010628| positive regulation of gene expression NR1I2;RARG;GPER1 GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process BECN1;ALB;RARG 676:[DB02466 DB01193] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 677:[DB02466 DB01624] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0008284| positive regulation of cell proliferation HTR2A;RARG;ADRA2A GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG 678:[DB02466 DB00171] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0043066| negative regulation of apoptotic process ASNS;AKT1;RARG;ARAF;PRKAA1 GO:0071300| cellular response to retinoic acid RARG;ABL2;ABCA1 GO:0010628| positive regulation of gene expression PRKAA1;RARG;ACVR1B GO:0006355| regulation of transcription, DNA-dependent PRKAA1;ABL1;RARG;CSNK2A1;ABCG1;ACVRL1;ACVR1B GO:0008284| positive regulation of cell proliferation CSNK2A1;AKT1;PRKAA1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ACVRL1;ACVR1B;ACVR1;AKT1 GO:0043065| positive regulation of apoptotic process AKT1;ABL1;APAF1;RARG GO:0001843| neural tube closure RARG;APAF1;ABL1 GO:0031641| regulation of myelination AKT1;RARG GO:0006351| transcription, DNA-dependent PRKAA1;RARG;CSNK2A1;PPP5C GO:0008285| negative regulation of cell proliferation ACVRL1;RARG;CSNK2B GO:0010468| regulation of gene expression PIK3CA;RARG 679:[DB02466 DB05766] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;DRD3;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation DRD2;RARG 680:[DB02466 DB08883] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 681:[DB02466 DB00445] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0006351| transcription, DNA-dependent CHD1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A GO:0006355| regulation of transcription, DNA-dependent CHD1;RARG GO:0043065| positive regulation of apoptotic process RARG;TOP2A 682:[DB02466 DB06738] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0043065| positive regulation of apoptotic process GRIN1;GRIN2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;GRIN1 GO:0008285| negative regulation of cell proliferation RARG;OPRM1 683:[DB02466 DB05223] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;HDAC2 GO:0043066| negative regulation of apoptotic process HDAC1;HDAC2;RARG;HDAC3 GO:0006355| regulation of transcription, DNA-dependent HDAC2;RARG;HDAC3;HDAC6;HDAC1 GO:0008284| positive regulation of cell proliferation HDAC1;HDAC2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;HDAC2;RARG;HDAC3 GO:0008285| negative regulation of cell proliferation HDAC1;RARG GO:0006351| transcription, DNA-dependent HDAC6;HDAC1;HDAC2;RARG;HDAC3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC1;HDAC2;HDAC3;RARG 684:[DB02466 DB12698] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways 685:[DB02466 DB00031] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;CALR GO:0008285| negative regulation of cell proliferation RARG;PLG GO:0006355| regulation of transcription, DNA-dependent RARG;CALR GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;RARG GO:0008284| positive regulation of cell proliferation CALR;RARG GO:0010628| positive regulation of gene expression RARG;CALR GO:0043066| negative regulation of apoptotic process SERPINB2;PLAUR;RARG 686:[DB02466 DB02187] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARG GO:0006355| regulation of transcription, DNA-dependent ESR1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RARG 687:[DB02466 DB01207] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways 688:[DB02466 DB01194] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways 689:[DB02466 DB00240] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 690:[DB02466 DB08910] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08910|Pomalidomide CRBN;TNF;PTGS2;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;RARG GO:0043065| positive regulation of apoptotic process RARG;TNF;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0010628| positive regulation of gene expression RARG;TNF GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;RARG GO:0008285| negative regulation of cell proliferation PTGS2;RARG 691:[DB02466 DB00860] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RARG 692:[DB02466 DB00846] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG 693:[DB02466 DB06209] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0045596| negative regulation of cell differentiation RARG;P2RY12 694:[DB02466 DB01125] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01125|Anisindione GGCX common genes common pathways 695:[DB02466 DB00851] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043010| camera-type eye development CYP1A1;RARG 696:[DB02466 DB00481] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ESR2;ESR1 GO:0010628| positive regulation of gene expression RARG;SERPINB9 GO:0043066| negative regulation of apoptotic process SERPINB9;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;ESR2;ESR1 GO:0008285| negative regulation of cell proliferation TFF1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;ESR2;ESR1 GO:0006351| transcription, DNA-dependent ESR2;RARG;ESR1 697:[DB02466 DB01009] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0008285| negative regulation of cell proliferation PTGS2;RARG 698:[DB02466 DB01536] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation AKR1C3;RARG 699:[DB02466 DB11967] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0008285| negative regulation of cell proliferation IL6;RARG;IL1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TNF GO:0010468| regulation of gene expression CYP1A2;RARG GO:0010628| positive regulation of gene expression RARG;IL1B;IL6;TNF GO:0043066| negative regulation of apoptotic process RARG;IL6 GO:0043065| positive regulation of apoptotic process RARG;IL6;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;IL6;RARG;IL1B GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0008284| positive regulation of cell proliferation IL1B;RARG;IL6 700:[DB02466 DB00562] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways 701:[DB02466 DB01370] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation APP;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;RARG GO:0010468| regulation of gene expression APP;RARG GO:0010628| positive regulation of gene expression APP;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0043065| positive regulation of apoptotic process APP;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;APP 702:[DB02466 DB01114] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0071300| cellular response to retinoic acid RARG;SLC6A4 703:[DB02466 DB00054] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways 704:[DB02466 DB00461] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0043066| negative regulation of apoptotic process MPO;RARG;PTGS2 705:[DB02466 DB00005] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TNF GO:0043065| positive regulation of apoptotic process LTA;TNF;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;RARG GO:0043068| positive regulation of programmed cell death TNF;RARG GO:0010628| positive regulation of gene expression RARG;TNF 706:[DB02466 DB00310] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00310|Chlorthalidone SLC12A1 common genes common pathways 707:[DB02466 DB00216] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2B;RARG GO:0043066| negative regulation of apoptotic process HTR2B;RARG 708:[DB02466 DB00975] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process ADA;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;RCAN1 709:[DB02466 DB00528] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways 710:[DB02466 DB05075] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;CSK GO:0043066| negative regulation of apoptotic process FLT4;RARG;KDR GO:0008284| positive regulation of cell proliferation RARG;KDR;FLT4;FLT1 711:[DB02466 DB01100] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01100|Pimozide DRD2;DRD3;KCNH2;CALM1;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008284| positive regulation of cell proliferation RARG;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 712:[DB02466 DB00983] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 713:[DB02466 DB00763] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 714:[DB02466 DB08868] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0008284| positive regulation of cell proliferation HDAC1;SPHK1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;HDAC1 GO:0043066| negative regulation of apoptotic process HDAC1;RARG;SPHK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;HDAC1 GO:0006351| transcription, DNA-dependent RARG;HDAC1 GO:0008285| negative regulation of cell proliferation RARG;HDAC1 715:[DB02466 DB00575] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00575|Clonidine ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP3A5;SLC22A3;SLC22A5;SLC22A4;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 716:[DB02466 DB08907] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 717:[DB02466 DB12248] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12248|Tulobuterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 718:[DB02466 DB11575] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 719:[DB02466 DB14542] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0043065| positive regulation of apoptotic process RARG;ANXA1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG 720:[DB02466 DB11574] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways 721:[DB02466 DB00583] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process MPO;RARG 722:[DB02466 DB05281] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0008284| positive regulation of cell proliferation BCL2;RARG GO:0043066| negative regulation of apoptotic process BCL2;RARG GO:0010468| regulation of gene expression BCL2;RARG GO:0008285| negative regulation of cell proliferation RARG;BCL2 723:[DB02466 DB00158] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0008284| positive regulation of cell proliferation RARG;FOLR2 724:[DB02466 DB00901] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00901|Bitolterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 725:[DB02466 DB01041] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01041|Thalidomide CRBN;TNF;NFKB1;FGFR2;PTGS2;ORM1;ORM2;CYP2C19;CYP1A1;CYP2E1;CYP2C9;PTGS1;PTGS2;CYP3A5 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;FGFR2;RARG;NFKB1 GO:0048608| reproductive structure development FGFR2;RARG GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0060349| bone morphogenesis RARG;FGFR2 GO:0006351| transcription, DNA-dependent NFKB1;RARG GO:0043065| positive regulation of apoptotic process RARG;PTGS2;TNF GO:0006355| regulation of transcription, DNA-dependent NFKB1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;FGFR2;NFKB1;RARG GO:0008284| positive regulation of cell proliferation RARG;FGFR2;PTGS2 GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0071300| cellular response to retinoic acid RARG;FGFR2 GO:0060348| bone development RARG;FGFR2 GO:0010628| positive regulation of gene expression RARG;TNF GO:0043010| camera-type eye development CYP1A1;RARG GO:0035264| multicellular organism growth RARG;FGFR2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG;NFKB1 726:[DB02466 DB01303] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent HDAC2;RARG;ADORA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;RARG GO:0008284| positive regulation of cell proliferation HDAC2;RARG GO:0043066| negative regulation of apoptotic process RARG;HDAC2;ADORA1;PDE3A GO:0071300| cellular response to retinoic acid HDAC2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;HDAC2 GO:0006351| transcription, DNA-dependent HDAC2;RARG GO:0008285| negative regulation of cell proliferation ADORA1;ADORA2A;RARG 727:[DB02466 DB08341] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0008284| positive regulation of cell proliferation PTK2B;RARG GO:0071300| cellular response to retinoic acid PTK2B;RARG GO:0043066| negative regulation of apoptotic process RARG;PTK2B GO:0008285| negative regulation of cell proliferation PTK2B;RARG 728:[DB02466 DB00234] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00234|Reboxetine SLC6A2;CYP3A4;CYP2D6;ABCB1 common genes common pathways 729:[DB02466 DB00535] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;MPO 730:[DB02466 DB11799] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;POU2F2 GO:0006355| regulation of transcription, DNA-dependent POU2F2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;POU2F2 731:[DB02466 DB12329] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways 732:[DB02466 DB01365] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 733:[DB02466 DB01011] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways 734:[DB02466 DB00219] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00219|Oxyphenonium CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 735:[DB02466 DB13139] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 736:[DB02466 DB00313] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes common pathways GO:0010468| regulation of gene expression RARG;PPARA;CYP1A2 GO:0032526| response to retinoic acid RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;PPARA;PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;HDAC9;HDAC2;PPARG;PPARA;PPARD GO:0006351| transcription, DNA-dependent PPARD;PPARG;PPARA;RARG;HDAC9;HDAC2 GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG;PPARA;PPARD GO:0008285| negative regulation of cell proliferation PPARG;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;HDAC2;PPARA;PPARG GO:0008284| positive regulation of cell proliferation RARG;HDAC2;PPARD GO:0006355| regulation of transcription, DNA-dependent HDAC2;RARG;HDAC9;PPARG;PPARA;PPARD GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0043066| negative regulation of apoptotic process HDAC2;ALB;RARG;PPARD GO:0010628| positive regulation of gene expression PPARD;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG;HDAC2 737:[DB02466 DB00476] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00476|Duloxetine SLC6A4;SLC6A2;SLC6A3;CYP1A2;CYP2D6;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0071300| cellular response to retinoic acid RARG;SLC6A4 738:[DB02466 DB11963] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;EGFR GO:0008284| positive regulation of cell proliferation RARG;EGFR 739:[DB02466 DB00586] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00586|Diclofenac PTGS2;PTGS1;ALOX5;SCN4A;ASIC1;KCNQ2;KCNQ3;PLA2G2A;CYP2C9;CYP2C19;CYP1A2;CYP2C8;UGT1A1;UGT2B7;PTGS1;CYP3A4;CYP1A1;CYP2B6;CYP2C18;CYP2E1;TTR;ALB;ABCC4;ABCB1;ABCC1;SLC22A6;SLC22A8;SLCO1C1;SLC22A11;SLCO1B1;ABCB11 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043066| negative regulation of apoptotic process PTGS2;RARG;ALB GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG 740:[DB02466 DB14512] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG;PGR GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG;PGR GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PGR;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;PGR;RARG 741:[DB02466 DB00185] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 742:[DB02466 DB00887] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0035264| multicellular organism growth SLC12A5;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 743:[DB02466 DB09325] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 744:[DB02466 DB06626] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008284| positive regulation of cell proliferation RARG;KDR;FLT4;FLT1 GO:0043066| negative regulation of apoptotic process FLT4;RARG;KDR 745:[DB02466 DB00677] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0008285| negative regulation of cell proliferation BCHE;RARG GO:0060041| retina development in camera-type eye RARG;ACHE 746:[DB02466 DB00136] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0010628| positive regulation of gene expression VDR;RARG GO:0009952| anterior/posterior pattern specification HOXA10;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HOXA10;RARG;VDR GO:0006355| regulation of transcription, DNA-dependent RARG;VDR;HOXA10 GO:0043401| steroid hormone mediated signaling pathway RARG;VDR GO:0008285| negative regulation of cell proliferation VDR;RARG GO:0006351| transcription, DNA-dependent HOXA10;RARG;VDR GO:0006367| transcription initiation from RNA polymerase II promoter VDR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;RARG GO:0010468| regulation of gene expression RARG;HOXA10 747:[DB02466 DB00776] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 748:[DB02466 DB14544] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0043065| positive regulation of apoptotic process ANXA1;RARG GO:0043066| negative regulation of apoptotic process RARG;ANXA1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RARG 749:[DB02466 DB05266] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0035264| multicellular organism growth PDE4D;RARG GO:0043066| negative regulation of apoptotic process RARG;PDE3A 750:[DB02466 DB01427] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;RARG GO:0043068| positive regulation of programmed cell death RARG;TNF GO:0010628| positive regulation of gene expression RARG;TNF GO:0043066| negative regulation of apoptotic process RARG;PDE3A GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TNF 751:[DB02466 DB00349] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways 752:[DB02466 DB05229] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways 753:[DB02466 DB01394] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01394|Colchicine TUBB1;TUBB;CYP3A4;CYP2B6;CYP2C8;CYP2E1;ABCB4;SLC22A3;ABCB1;ABCC1 common genes common pathways 754:[DB02466 DB14541] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process ANXA1;RARG GO:0043065| positive regulation of apoptotic process ANXA1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG 755:[DB02466 DB01037] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01037|Selegiline MAOB;MAOA;CYP2B6;CYP3A4;CYP2A6;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 756:[DB02466 DB01268] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01268|Sunitinib PDGFRB;FLT1;KIT;KDR;FLT4;FLT3;CSF1R;PDGFRA;CYP3A5;CYP3A7;CYP3A4;ABCC4;ABCB1;ABCC2;ABCG2 common genes common pathways GO:0008284| positive regulation of cell proliferation PDGFRB;FLT4;FLT3;FLT1;RARG;PDGFRA;KDR;CSF1R;KIT GO:0043065| positive regulation of apoptotic process RARG;PDGFRB GO:0043066| negative regulation of apoptotic process PDGFRB;FLT4;RARG;CSF1R;KDR GO:0010628| positive regulation of gene expression RARG;KIT GO:0032526| response to retinoic acid PDGFRB;RARG GO:0008285| negative regulation of cell proliferation RARG;CSF1R 757:[DB02466 DB00363] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00363|Clozapine DRD2;HTR2A;DRD1;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;HRH4;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALY;GSTP1;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2C19;CYP2A6;CYP2C8;FMO3;UGT1A4;CYP2E1;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process GSTP1;RARG GO:0010628| positive regulation of gene expression DRD1;RARG GO:0008284| positive regulation of cell proliferation CHRM1;HTR1A;DRD3;HTR2A;ADRA2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;RARG GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2;CYP1B1 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 758:[DB02466 DB00928] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00928|Azacitidine DNMT1;CDA common genes common pathways GO:0010628| positive regulation of gene expression RARG;DNMT1 GO:0006355| regulation of transcription, DNA-dependent DNMT1;RARG GO:0006351| transcription, DNA-dependent DNMT1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DNMT1 GO:0010468| regulation of gene expression RARG;DNMT1 759:[DB02466 DB00564] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00564|Carbamazepine SCN5A;CHRNA4;CHRNB2;NR1I2;CYP3A4;CYP2C8;CYP1A2;CYP2C9;CYP2C19;CYP2B6;CYP3A5;CYP3A7;UGT2B7;UGT1A1;ABCB1;RALBP1;ABCC2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG 760:[DB02466 DB13520] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13520|Metergoline SCN2A common genes common pathways 761:[DB02466 DB09059] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0010628| positive regulation of gene expression AVPR2;RARG GO:0008284| positive regulation of cell proliferation AVPR1A;RARG;AVPR2 762:[DB02466 DB01454] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0008284| positive regulation of cell proliferation HTR2B;RARG;HTR2A 763:[DB02466 DB00204] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways 764:[DB02466 DB00813] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00813|Fentanyl OPRM1;OPRD1;OPRK1;ABCB1;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 765:[DB02466 DB00914] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;PRKAA1 GO:0010628| positive regulation of gene expression PRKAA1;RARG GO:0006355| regulation of transcription, DNA-dependent PRKAA1;RARG GO:0008284| positive regulation of cell proliferation RARG;PRKAA1 GO:0006351| transcription, DNA-dependent RARG;PRKAA1 766:[DB02466 DB00469] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG 767:[DB02466 DB00454] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00454|Meperidine OPRK1;GRIN1;GRIN2B;GRIN2A;GRIN2C;GRIN2D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;OPRM1;SLC6A3;SLC6A2;SLC6A4;CES1;CYP3A4;CYP2C19;CYP2B6;CYP2D6;CYP1A2;ALB;ORM1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation RARG;OPRM1 GO:0043065| positive regulation of apoptotic process RARG;GRIN2A;GRIN1 GO:0008284| positive regulation of cell proliferation CHRM1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;RARG GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0043066| negative regulation of apoptotic process ALB;RARG 768:[DB02466 DB00489] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 769:[DB02466 DB01015] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;RARG;ALB 770:[DB02466 DB00321] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00321|Amitriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;OPRD1;OPRK1;NTRK1;NTRK2;ADRA1A;ADRA1D;ADRA2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCNQ2;KCNA1;KCND2;KCND3;HRH2;HRH4;SIGMAR1;HTR2C;ADRA1B;HTR7;HTR1D;OPRM1;HTR1B;HTR6;KCNQ3;ADRB1;ADRB2;ADRB3;CYP2D6;CYP1A2;CYP2C19;CYP2C9;CYP3A4;CYP3A5;CYP2B6;CYP2C8;CYP2E1;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression NTRK2;RARG;SLC6A4 GO:0043066| negative regulation of apoptotic process NTRK1;RARG;ALB GO:0048732| gland development RARG;HRH2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0043068| positive regulation of programmed cell death RARG;NTRK1 GO:0008284| positive regulation of cell proliferation ADRA1D;HTR1A;CHRM1;HTR2A;NTRK2;ADRA2A;RARG GO:0008285| negative regulation of cell proliferation NTRK1;OPRM1;RARG;ADRA1A GO:0060041| retina development in camera-type eye NTRK2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 771:[DB02466 DB02261] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways 772:[DB02466 DB00248] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;DRD3;HTR1A;ADRA1D;RARG;HTR2B;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2;ADRB2;DRD3 GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 773:[DB02466 DB00209] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 774:[DB02466 DB00359] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes common pathways 775:[DB02466 DB00761] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0035264| multicellular organism growth SLC12A5;RARG 776:[DB02466 DB01028] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 777:[DB02466 DB05104] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05104|Asimadoline OPRK1 common genes common pathways 778:[DB02466 DB09071] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 779:[DB02466 DB00900] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 780:[DB02466 DB00977] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR1I2;RARG GO:0006351| transcription, DNA-dependent ESR1;NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I2;ESR1 781:[DB02466 DB00246] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 GO:0008284| positive regulation of cell proliferation CHRM1;HTR1A;DRD3;HTR2A;ADRA2A;RARG GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2;ADRA1A 782:[DB02466 DB00907] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0008285| negative regulation of cell proliferation BCHE;RARG 783:[DB02466 DB00605] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0006351| transcription, DNA-dependent PPARD;MAPK3;RARG GO:0043401| steroid hormone mediated signaling pathway PPARD;RARG GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARD GO:0043066| negative regulation of apoptotic process AKR1B1;PPARD;PTGS2;RARG;ALB GO:0043010| camera-type eye development RARG;CYP1A1 GO:0010628| positive regulation of gene expression MAPK3;PPARD;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;MAPK3 GO:0008284| positive regulation of cell proliferation RARG;PPARD;PTGS2 GO:0006355| regulation of transcription, DNA-dependent RARG;PPARD GO:0060324| face development MAPK3;RARG GO:0043065| positive regulation of apoptotic process RARG;PTGS2 784:[DB02466 DB05838] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05838|OPC-51803 AVPR2 common genes common pathways GO:0010628| positive regulation of gene expression AVPR2;RARG GO:0008284| positive regulation of cell proliferation AVPR2;RARG 785:[DB02466 DB01355] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRNA7 786:[DB02466 DB00651] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADORA2A;ADORA1 GO:0006355| regulation of transcription, DNA-dependent RARG;ADORA2A GO:0043066| negative regulation of apoptotic process ADORA1;RARG GO:0035264| multicellular organism growth PDE4D;RARG 787:[DB02466 DB06230] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 788:[DB02466 DB00457] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;RARG 789:[DB02466 DB09048] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways 790:[DB02466 DB09216] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043066| negative regulation of apoptotic process RARG;PTGS2 791:[DB02466 DB00820] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways 792:[DB02466 DB08889] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways 793:[DB02466 DB06728] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 794:[DB02466 DB00687] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;AR;NR3C2;NR3C1 GO:0048608| reproductive structure development AR;RARG GO:0010468| regulation of gene expression RARG;AR GO:0008285| negative regulation of cell proliferation RARG;AR GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C2;AR;NR3C1 GO:0006351| transcription, DNA-dependent NR3C2;AR;RARG;NR3C1 GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0006355| regulation of transcription, DNA-dependent AR;NR3C2;RARG;NR3C1 GO:0008284| positive regulation of cell proliferation RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;AR;NR3C1 GO:0010628| positive regulation of gene expression RARG;AR GO:0035264| multicellular organism growth RARG;AR 795:[DB02466 DB01544] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0043065| positive regulation of apoptotic process TSPO;RARG 796:[DB02466 DB04743] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04743|Nimesulide PTGS2;PLA2G2E;LTF;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0006351| transcription, DNA-dependent LTF;RARG GO:0060349| bone morphogenesis RARG;LTF GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent RARG;LTF GO:0043066| negative regulation of apoptotic process PTGS2;LTF;RARG 797:[DB02466 DB09477] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways 798:[DB02466 DB00571] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;ADRB2 GO:0008284| positive regulation of cell proliferation RARG;HTR1A GO:0043010| camera-type eye development RARG;CYP1A1 GO:0010468| regulation of gene expression RARG;CYP1A2 799:[DB02466 DB00806] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;ADORA2A GO:0043066| negative regulation of apoptotic process RARG;ADORA1 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008285| negative regulation of cell proliferation ADORA2A;ADORA1;RARG 800:[DB02466 DB14146] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 801:[DB02466 DB00808] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00808|Indapamide SLC12A3;CYP3A4 common genes common pathways 802:[DB02466 DB00159] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;PPARD;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;RARG GO:0006355| regulation of transcription, DNA-dependent FADS1;PPARG;PPARA;PPARD;RARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2;RARG;TRPV1 GO:0043066| negative regulation of apoptotic process ALB;RARG;PTGS2;PPARD GO:0010628| positive regulation of gene expression PPARD;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0032526| response to retinoic acid RARG;PPARG GO:0010468| regulation of gene expression PPARA;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARA;PPARG;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;RARG;PPARD;PPARA;PPARG GO:0006351| transcription, DNA-dependent PPARD;PPARA;PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARA;PPARG;RARG GO:0008285| negative regulation of cell proliferation RARG;FABP7;PTGS2;PPARG 803:[DB02466 DB00951] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00951|Isoniazid katG;CYP2C8;CYP1A2;CYP3A4;CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2D6;CYP2C19;NAT2;CYP2A6;CYP2C8;ALB common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG 804:[DB02466 DB00988] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0006351| transcription, DNA-dependent POU5F1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter POU5F1;RARG;DRD3 GO:0010468| regulation of gene expression RARG;POU5F1 GO:0071300| cellular response to retinoic acid SLC6A4;RARG GO:0010628| positive regulation of gene expression SLC6A4;DRD1;RARG GO:0043066| negative regulation of apoptotic process RARG;SOD1 GO:0043065| positive regulation of apoptotic process RARG;SOD1 GO:0006355| regulation of transcription, DNA-dependent POU5F1;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR1A;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;POU5F1;RARG;DRD3 805:[DB02466 DB00317] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;EGFR GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043066| negative regulation of apoptotic process EGFR;RARG;ALB 806:[DB02466 DB01184] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RARG;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DRD3 GO:0008285| negative regulation of cell proliferation RARG;DRD2 807:[DB02466 DB11915] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways 808:[DB02466 DB01579] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 809:[DB02466 DB06663] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation SSTR3;SSTR1;SSTR2;RARG;SSTR5 GO:1990830| SSTR1;RARG 810:[DB02466 DB00082] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;RARG 811:[DB02466 DB00870] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 812:[DB02466 DB00899] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 813:[DB02466 DB01103] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways 814:[DB02466 DB13165] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0010628| positive regulation of gene expression RARG;ROCK1;ROCK2 815:[DB02466 DB00686] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0035116| embryonic hindlimb morphogenesis FGF4;RARG GO:0010468| regulation of gene expression RARG;FGF4 GO:0043066| negative regulation of apoptotic process FGF4;RARG GO:0010628| positive regulation of gene expression FGF4;RARG GO:1990830| RARG;FGF4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;FGF2;RARG;FGF4 GO:0008284| positive regulation of cell proliferation FGF1;FGF2;RARG;FGF4 816:[DB02466 DB00091] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00091|Ciclosporin CAMLG;PPP3R2;PPIA;PPIF;CYP3A7;CYP3A5;CYP3A4;CYP2C19;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCC3;ABCB11;ABCC1;SLCO1A2;SLC10A2;SLC10A1;SLC22A6;ABCC10;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;PPIF 817:[DB02466 DB11156] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 818:[DB02466 DB05131] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05131|TTP889 F9 common genes common pathways 819:[DB02466 DB09546] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways 820:[DB02466 DB08496] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08496|(R)-warfarin CYP2C8;CYP2C9;CYP2C18;CYP2C19;CYP1A2;CYP1A1;CYP3A4;ALB common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0043010| camera-type eye development RARG;CYP1A1 821:[DB02466 DB08879] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08879|Belimumab TNFSF13B common genes common pathways GO:0008284| positive regulation of cell proliferation TNFSF13B;RARG 822:[DB02466 DB01325] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways 823:[DB02466 DB01353] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG 824:[DB02466 DB00230] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways 825:[DB02466 DB00588] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PGR;NR3C2;RARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C2;PGR;NR3C1 GO:0043401| steroid hormone mediated signaling pathway PGR;NR3C2;RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PGR;NR3C1 GO:0006355| regulation of transcription, DNA-dependent PGR;RARG;NR3C2;NR3C1 826:[DB02466 DB08828] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0010468| regulation of gene expression SMO;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;SMO GO:0043066| negative regulation of apoptotic process RARG;ALB;SMO GO:0035264| multicellular organism growth RARG;SMO GO:0010628| positive regulation of gene expression SMO;RARG GO:0060070| canonical Wnt receptor signaling pathway SMO;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;SMO GO:0008284| positive regulation of cell proliferation RARG;SMO GO:0009952| anterior/posterior pattern specification RARG;SMO 827:[DB02466 DB07449] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PADI4;RARG GO:0006351| transcription, DNA-dependent PADI4;RARG 828:[DB02466 DB00819] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways GO:0071300| cellular response to retinoic acid AQP1;RARG GO:0043066| negative regulation of apoptotic process RARG;AQP1 829:[DB02466 DB00284] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 830:[DB02466 DB01067] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RARG GO:0032526| response to retinoic acid PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0008285| negative regulation of cell proliferation PPARG;RARG GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0043065| positive regulation of apoptotic process RARG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0071300| cellular response to retinoic acid RARG;PPARG 831:[DB02466 DB01159] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0060041| retina development in camera-type eye RHO;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0043065| positive regulation of apoptotic process RARG;GRIN2A;KCNMA1 832:[DB02466 DB01013] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0043010| camera-type eye development RARG;CYP1A1 833:[DB02466 DB04868] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;RARG GO:0008284| positive regulation of cell proliferation RARG;KIT GO:0043065| positive regulation of apoptotic process RARG;ABL1 GO:0010628| positive regulation of gene expression RARG;KIT GO:0001843| neural tube closure ABL1;RARG 834:[DB02466 DB14066] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways 835:[DB02466 DB00703] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways 836:[DB02466 DB01069] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01069|Promethazine HRH1;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;HTR2A;CALM1;HRH2;CYP2D6;CYP2B6;CYP2C9;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG GO:0048732| gland development HRH2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation RARG;CHRM1;HTR2A 837:[DB02466 DB00203] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00203|Sildenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2D6;CYP1A1;CYP2E1;ABCC4;ABCC5;ABCC10;SLCO1B1;ABCB1 common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 838:[DB02466 DB06470] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways 839:[DB02466 DB01340] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways 840:[DB02466 DB00009] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PLG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;SERPINE1 GO:0043066| negative regulation of apoptotic process PLAUR;RARG 841:[DB02466 DB01628] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01628|Etoricoxib PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation PTGS2;RARG 842:[DB02466 DB01001] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 843:[DB02466 DB01002] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 844:[DB02466 DB04842] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation RARG;HTR2A 845:[DB02466 DB01392] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;DRD3 GO:0008284| positive regulation of cell proliferation RARG;HTR2B;ADRA2A;HTR2A;DRD3;HTR1A GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2 846:[DB02466 DB01809] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0060041| retina development in camera-type eye RET;RARG GO:0008284| positive regulation of cell proliferation HCK;RARG GO:0010628| positive regulation of gene expression RET;RARG GO:0071300| cellular response to retinoic acid RET;RARG GO:0043066| negative regulation of apoptotic process RARG;HCK 847:[DB02466 DB00833] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;MPO 848:[DB02466 DB00591] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0006351| transcription, DNA-dependent NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;RARG GO:0043065| positive regulation of apoptotic process RARG;ANXA1 GO:0043066| negative regulation of apoptotic process ANXA5;ANXA4;ANXA1;RARG 849:[DB02466 DB01142] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01142|Doxepin HRH1;HRH2;SLC6A2;SLC6A4;HTR2A;HTR2B;HTR2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR1A;ADRA2A;ADRA2B;ADRA2C;DRD2;HTR6;HRH4;KCNH2;CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;ORM1;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation HTR2B;ADRA2A;RARG;HTR1A;CHRM1;HTR2A;ADRA1D GO:0048732| gland development RARG;HRH2 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 850:[DB02466 DB05271] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RARG;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;HTR1A;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG 851:[DB02466 DB12483] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways GO:0010468| regulation of gene expression PIK3CA;RARG GO:0010628| positive regulation of gene expression PIK3CD;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB 852:[DB02466 DB11693] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPP3R1 853:[DB02466 DB05152] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05152|NGX267 CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 854:[DB02466 DB00432] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways GO:0031641| regulation of myelination TYMP;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB 855:[DB02466 DB00731] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0032526| response to retinoic acid RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARG GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RARG GO:0008285| negative regulation of cell proliferation RARG;PPARG 856:[DB02466 DB04932] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0008285| negative regulation of cell proliferation ADORA1;ADORA2A;RARG GO:0043066| negative regulation of apoptotic process ADORA1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;ADORA2A 857:[DB02466 DB00334] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00334|Olanzapine HTR2A;DRD2;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR5A;DRD1;DRD5;HRH2;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;ADRB1;ADRB2;ADRB3;CYP1A2;CYP2D6;FMO3;CYP2C19;CYP3A4;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;RARG GO:0008284| positive regulation of cell proliferation RARG;ADRA2A;HTR2B;DRD3;HTR2A;CHRM1;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG;ADRB2;DRD3 GO:0048732| gland development HRH2;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG;HTR2B GO:0010628| positive regulation of gene expression RARG;DRD1 858:[DB02466 DB00783] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00783|Estradiol ESR1;ESR2;NR1I2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP3A4;CYP1A2;CYP3A5;CYP3A7;UGT1A1;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;GPER1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GPER1;ESRRG;ESR2;RARG;NCOA2;ESR1;NR1I2 GO:0006355| regulation of transcription, DNA-dependent RARG;ESR2;ESRRG;NR1I2;ESR1;NCOA2 GO:0043065| positive regulation of apoptotic process RARG;GPER1;CYP1B1 GO:0043066| negative regulation of apoptotic process BECN1;RARG;ALB GO:0043010| camera-type eye development RARG;CYP1A1 GO:0010628| positive regulation of gene expression NR1I2;RARG;GPER1 GO:0032526| response to retinoic acid RARG;HSD17B2 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1I2;ESR2;RARG;ESRRG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;ESR2;RARG GO:0006351| transcription, DNA-dependent NCOA2;NR1I2;ESR1;ESRRG;RARG;ESR2 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RARG GO:0043401| steroid hormone mediated signaling pathway ESRRG;GPER1;RARG;ESR2;NR1I2;ESR1 GO:0008285| negative regulation of cell proliferation BECN1;RARG;CYP1B1;GPER1 859:[DB02466 DB14543] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0043065| positive regulation of apoptotic process ANXA1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 GO:0043066| negative regulation of apoptotic process RARG;ANXA1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;RARG 860:[DB02466 DB01221] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2;OPRM1;BCHE GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2;NOS1 GO:0008284| positive regulation of cell proliferation CHRNA7;RARG;HTR2B;HTR2A;HTR1A;CHRM1 GO:0043066| negative regulation of apoptotic process RARG;HTR2B 861:[DB02466 DB05541] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways 862:[DB02466 DB00740] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043010| camera-type eye development CYP1A1;RARG 863:[DB02466 DB00297] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways 864:[DB02466 DB00335] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG 865:[DB02466 DB14068] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways 866:[DB02466 DB01285] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;CYP27B1 GO:0010628| positive regulation of gene expression RARG;CRH GO:0008284| positive regulation of cell proliferation CRH;RARG 867:[DB02466 DB08896] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0043068| positive regulation of programmed cell death RARG;NTRK1 GO:0008284| positive regulation of cell proliferation PDGFRA;KDR;KIT;RARG;FGFR2;FLT1;FLT4;PDGFRB;FGFR1;DDR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;FGFR2;RAF1 GO:0006355| regulation of transcription, DNA-dependent FGFR1;MAPK11;ABL1;RARG GO:0060324| face development RAF1;RARG;BRAF GO:0043065| positive regulation of apoptotic process PDGFRB;ABL1;RARG GO:0043066| negative regulation of apoptotic process RARG;KDR;TEK;BRAF;NTRK1;FLT4;PDGFRB;RAF1 GO:0035264| multicellular organism growth FGFR2;RARG GO:0010628| positive regulation of gene expression RARG;KIT;MAPK11;BRAF;RET GO:0060348| bone development FGFR2;RARG GO:0071300| cellular response to retinoic acid RET;RARG;FGFR2 GO:0032526| response to retinoic acid RARG;PDGFRB GO:0010468| regulation of gene expression FGFR1;RARG GO:0048608| reproductive structure development RARG;FGFR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;RARG;FRK;FGFR2 GO:0006351| transcription, DNA-dependent RARG;MAPK11;FGFR1 GO:0060349| bone morphogenesis FGFR2;RARG GO:0001843| neural tube closure RARG;ABL1 GO:0060041| retina development in camera-type eye RET;RARG GO:0008285| negative regulation of cell proliferation FRK;RARG;NTRK1;RAF1 868:[DB02466 DB00015] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0043066| negative regulation of apoptotic process PLAUR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;RARG GO:0008285| negative regulation of cell proliferation PLG;RARG 869:[DB02466 DB00752] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 870:[DB02466 DB00277] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0006351| transcription, DNA-dependent PARP1;RARG;CPNE1;HDAC2 GO:0008285| negative regulation of cell proliferation RARG;CYP1B1;ADORA2A;ADORA1 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC2;RARG;PARP1 GO:0043066| negative regulation of apoptotic process ADA;HDAC2;RARG;PDE3A;ADORA1 GO:0043010| camera-type eye development CYP1A1;RARG GO:0071300| cellular response to retinoic acid HDAC2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;HDAC2;RARG GO:0008284| positive regulation of cell proliferation RARG;HDAC2 GO:0006355| regulation of transcription, DNA-dependent CPNE1;HDAC2;RARG;ADORA2A;PARP1 GO:0043065| positive regulation of apoptotic process RARG;CYP1B1 871:[DB02466 DB12789] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12789|Dinoprost PTGDR2 common genes common pathways 872:[DB02466 DB01244] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01244|Bepridil CACNA1A;CACNA1H;CACNA2D2;ATP1A1;KCNQ1;TNNC1;CALM1;PDE1B;PDE1A;KCNH2;CYP2D6;CYP3A4;ABCB1 common genes common pathways 873:[DB02466 DB01175] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0008284| positive regulation of cell proliferation RARG;CHRM1 874:[DB02466 DB00295] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 875:[DB02466 DB01393] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARD;PPARA;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RARG;RXRG;PPARD;RXRB;NR1I2;RXRA;PPARG;PPARA GO:0032526| response to retinoic acid RARG;PPARG;RXRA GO:0010468| regulation of gene expression RARG;PPARA GO:0008285| negative regulation of cell proliferation RARG;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA;RXRB;NR1I2;RXRA;PPARD;RXRG;RARG GO:0048384| retinoic acid receptor signaling pathway RXRA;RXRB;RARG;RXRG GO:0006351| transcription, DNA-dependent PPARD;PPARG;PPARA;RXRB;NR1I2;RXRA;RXRG;RARG GO:0043065| positive regulation of apoptotic process RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRG;RARG;PPARG;PPARA;RXRB;NR1I2;RXRA;PPARD GO:0008284| positive regulation of cell proliferation PPARD;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;RXRA;RXRB;NR1I2;RXRG;RARG GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0010628| positive regulation of gene expression PPARD;NR1I2;RARG GO:0043010| camera-type eye development CYP1A1;RXRA;RARG GO:0043066| negative regulation of apoptotic process RARG;PPARD 876:[DB02466 DB00492] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways 877:[DB02466 DB05443] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05443|ADL 10-0101 OPRK1 common genes common pathways 878:[DB02466 DB00563] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00563|Methotrexate DHFR;DHFR;AOX1;MTHFR;PGD;FPGS;TYMS;ATIC;GGH;CYP3A4;ALB;ABCC3;ABCC4;ABCC1;SLC22A6;ABCC10;SLC22A8;ABCC2;ABCB1;SLCO1A2;SLC16A1;ABCC11;SLCO1B3;SLC22A11;SLCO1C1;SLCO3A1;ABCG2;SLC22A7;SLC46A1;SLCO1B1;SLCO4C1;SLC19A1;FOLR1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 879:[DB02466 DB00217] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RARG GO:0008284| positive regulation of cell proliferation RARG;ADRA2A 880:[DB02466 DB01281] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01281|Abatacept CD80;CD86 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CD86 881:[DB02466 DB00709] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00709|Lamivudine pol;DCK;CMPK1;PGK1;NME1;NME2;PCYT1A;PCYT2;NT5C;ALB;ABCC1;SLC22A6;ABCG2;SLC22A1;SLC22A2;SLC22A3;ABCB1;ABCC4;ABCC3;ABCC2 common genes common pathways GO:0008285| negative regulation of cell proliferation NME1;RARG GO:0006351| transcription, DNA-dependent NME2;RARG GO:0006355| regulation of transcription, DNA-dependent NME2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NME2;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG;NME2 882:[DB02466 DB01090] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 883:[DB02466 DB00361] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways 884:[DB02466 DB00495] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00495|Zidovudine pol;TERT;CYP2A6;CYP2C8;CYP2C9;CYP3A4;TK1;UGT2B7;UGT1A1;ALB;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLC28A1;SLC29A2;ABCB1;ABCC4;ABCC5;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process TERT;RARG;ALB 885:[DB02466 DB09262] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG GO:0043066| negative regulation of apoptotic process ALB;RARG 886:[DB02466 DB01088] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0035264| multicellular organism growth PDE4D;RARG 887:[DB02466 DB05294] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;RARG;EGFR GO:0008284| positive regulation of cell proliferation VEGFA;RARG;EGFR GO:0071300| cellular response to retinoic acid PTK6;RET;RARG GO:0010628| positive regulation of gene expression VEGFA;RET;RARG GO:0043066| negative regulation of apoptotic process VEGFA;RARG;ALB;TEK;EGFR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;VEGFA GO:0060041| retina development in camera-type eye RET;RARG 888:[DB02466 DB00544] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0031641| regulation of myelination RARG;TYMP GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB 889:[DB02466 DB00542] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways 890:[DB02466 DB08870] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways GO:0043065| positive regulation of apoptotic process TNFRSF8;RARG GO:0008285| negative regulation of cell proliferation RARG;TNFRSF8 891:[DB02466 DB08873] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08873|Boceprevir CYP3A4;CYP3A5;ABCB1 common genes common pathways 892:[DB02466 DB09119] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways 893:[DB02466 DB00201] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 GO:0035264| multicellular organism growth ATM;PDE4D;RARG GO:0043066| negative regulation of apoptotic process PRKDC;PDE3A;ADORA1;RARG GO:0010628| positive regulation of gene expression RARG;PIK3CD;PIK3CB GO:0006355| regulation of transcription, DNA-dependent ADORA2A;PDE8A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PRKDC GO:0043065| positive regulation of apoptotic process CYP1B1;RARG;ATM;PRKDC GO:0008285| negative regulation of cell proliferation CYP1B1;RARG;ADORA2A;ADORA1 GO:0060041| retina development in camera-type eye RARG;PDE6B GO:0010468| regulation of gene expression CYP1A2;RARG;PIK3CA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PDE2A 894:[DB02466 DB00972] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00972|Azelastine HRH1;CYP1A2;CYP3A4;CYP2C19;CYP1A1;CYP3A5;CYP2C9;CYP2C8;CYP2D6;CYP2A6;CYP2B6;CYP2E1;ABCB1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 895:[DB02466 DB00774] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;KCNMA1 896:[DB02466 DB01567] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways 897:[DB02466 DB00480] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:1990830| TNFSF11;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNFSF11 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;RARG;CDH5 898:[DB02466 DB00771] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00771|Clidinium CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 899:[DB02466 DB00659] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0043065| positive regulation of apoptotic process GRIN1;GRIN2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;GRIN1 900:[DB02466 DB00412] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;RXRG;RXRA;RXRB;PPARA;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARG;PPARA;RXRB;RXRA;RXRG;RARG GO:0043065| positive regulation of apoptotic process PPARG;RARG GO:0043066| negative regulation of apoptotic process PPARD;RARG;ALB GO:0043010| camera-type eye development RARG;RXRA GO:0010628| positive regulation of gene expression PPARD;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0032526| response to retinoic acid RXRA;PPARG;RARG GO:0010468| regulation of gene expression RARG;CYP1A2;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA;RXRB;RXRA;PPARD;RXRG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;RXRA;PPARA;PPARG;PPARD GO:0006351| transcription, DNA-dependent RXRG;RARG;PPARD;PPARG;PPARA;RXRB;RXRA GO:0048384| retinoic acid receptor signaling pathway RXRG;RARG;RXRB;RXRA GO:0043401| steroid hormone mediated signaling pathway RXRG;RARG;PPARD;PPARG;PPARA;RXRB;RXRA GO:0008285| negative regulation of cell proliferation PPARG;RARG 901:[DB02466 DB01608] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0043401| steroid hormone mediated signaling pathway RARG;AR GO:0008285| negative regulation of cell proliferation AR;RARG GO:0006351| transcription, DNA-dependent AR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;AR GO:0010468| regulation of gene expression RARG;AR GO:0048608| reproductive structure development AR;RARG GO:0010628| positive regulation of gene expression RARG;DRD1;AR GO:0035264| multicellular organism growth RARG;AR GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0008284| positive regulation of cell proliferation ADRA2A;AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;AR 902:[DB02466 DB01119] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;KCNMA1 903:[DB02466 DB04908] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04908|Flibanserin HTR1A;HTR2A;DRD4;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;RARG 904:[DB02466 DB00842] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways 905:[DB02466 DB00184] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;RARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 906:[DB02466 DB04630] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0006351| transcription, DNA-dependent NR3C1;NR3C2;RARG GO:0043401| steroid hormone mediated signaling pathway NR3C2;RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;NR3C2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C2;RARG;NR3C1 907:[DB02466 DB00482] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00482|Celecoxib PTGS2;PDPK1;CA2;CA3;ABCB5;ABCG2;ABCB1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;ABCC4;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0006355| regulation of transcription, DNA-dependent PDPK1;RARG GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0006351| transcription, DNA-dependent PDPK1;RARG GO:0008285| negative regulation of cell proliferation RARG;PTGS2 908:[DB02466 DB01035] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;BCHE GO:0006351| transcription, DNA-dependent RARG;DNMT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;DNMT1 GO:0010468| regulation of gene expression DNMT1;RARG GO:0010628| positive regulation of gene expression RARG;DNMT1 GO:0006355| regulation of transcription, DNA-dependent DNMT1;RARG 909:[DB02466 DB00648] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0035264| multicellular organism growth AR;RARG GO:0010628| positive regulation of gene expression AR;RARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PGR;AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PGR;AR;RARG GO:0008284| positive regulation of cell proliferation RARG;AR GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0006351| transcription, DNA-dependent ESR1;PGR;AR;RARG GO:0008285| negative regulation of cell proliferation AR;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;AR;PGR;ESR1 GO:0048608| reproductive structure development RARG;AR GO:0010468| regulation of gene expression AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARG;AR;PGR 910:[DB02466 DB01238] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2;DRD3 GO:0008284| positive regulation of cell proliferation ADRA2A;RARG;HTR1A;CHRM1;HTR2A;DRD3 GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 911:[DB02466 DB06710] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0010628| positive regulation of gene expression RARG;AR GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0035264| multicellular organism growth AR;RARG GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0008284| positive regulation of cell proliferation AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RARG;AR GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;RARG GO:0043401| steroid hormone mediated signaling pathway ESR1;RARG;AR GO:0008285| negative regulation of cell proliferation RARG;AR GO:0006351| transcription, DNA-dependent RARG;AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG;AR GO:0010468| regulation of gene expression RARG;AR GO:0048608| reproductive structure development RARG;AR 912:[DB02466 DB07477] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB07477|Felbinac CTSL common genes common pathways 913:[DB02466 DB01156] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes common pathways 914:[DB02466 DB00496] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 915:[DB02466 DB00318] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 916:[DB02466 DB00443] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway NR3C1;RARG GO:0006351| transcription, DNA-dependent RARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent RARG;NR3C1 917:[DB02466 DB01217] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 918:[DB02466 DB01622] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 919:[DB02466 DB09286] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0043066| negative regulation of apoptotic process HTR2B;RARG GO:0010628| positive regulation of gene expression RARG;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;RARG GO:0008284| positive regulation of cell proliferation HTR2A;DRD3;ADRA1D;RARG;HTR2B;ADRA2A GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG 920:[DB02466 DB01062] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 921:[DB02466 DB00780] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways 922:[DB02466 DB01320] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 923:[DB02466 DB00500] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG;MPO;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;RARG 924:[DB02466 DB00804] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 GO:0008284| positive regulation of cell proliferation RARG;CHRM1 925:[DB02466 DB01115] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01115|Nifedipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CALM1;KCNA1;CACNA1H;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2A6;CYP2C8;CYP2D6;CYP2E1;CYP1A1;CYP2B6;ABCC3;ABCB1;ABCC2;SLCO1B1;ABCB11 common genes common pathways GO:0010628| positive regulation of gene expression NR1I2;RARG GO:0043010| camera-type eye development RARG;CACNA1C;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RARG GO:0006351| transcription, DNA-dependent RARG;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 926:[DB02466 DB09118] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043065| positive regulation of apoptotic process LDHA;RARG 927:[DB02466 DB11943] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 928:[DB02466 DB01558] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01558|Bromazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 929:[DB02466 DB08932] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes common pathways GO:0008284| positive regulation of cell proliferation EDNRB;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB;EDNRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDNRB;RARG 930:[DB02466 DB13975] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 931:[DB02466 DB00042] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 932:[DB02466 DB00254] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006351| transcription, DNA-dependent RARG;PADI4 GO:0006355| regulation of transcription, DNA-dependent PADI4;RARG 933:[DB02466 DB13955] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;GPER1;CYP1B1 GO:0006355| regulation of transcription, DNA-dependent ESRRG;ESR2;RARG;NCOA2;ESR1;NR1I2 GO:0008284| positive regulation of cell proliferation GPER1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;RARG;GPER1;ESRRG;ESR1;NR1I2;NCOA2 GO:0010628| positive regulation of gene expression RARG;GPER1;NR1I2 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0043066| negative regulation of apoptotic process BECN1;ALB;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;ESR2;RARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1;ESRRG;RARG;ESR2 GO:0032526| response to retinoic acid HSD17B2;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation RARG;GPER1;CYP1B1;BECN1 GO:0043401| steroid hormone mediated signaling pathway ESR2;RARG;GPER1;ESRRG;ESR1;NR1I2 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RARG GO:0006351| transcription, DNA-dependent NCOA2;NR1I2;ESR1;ESRRG;RARG;ESR2 934:[DB02466 DB00546] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways 935:[DB02466 DB14700] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14700|Damoctocog alfa pegol F8 common genes common pathways 936:[DB02466 DB00418] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0043065| positive regulation of apoptotic process GRIN2A;RARG;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;GRIN1 GO:0008284| positive regulation of cell proliferation CHRNA7;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 937:[DB02466 DB00428] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043010| camera-type eye development RARG;CYP1A1 938:[DB02466 DB09244] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;ADRA2A;RARG 939:[DB02466 DB11718] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation CCND1;RARG GO:0060324| face development RARG;BRAF GO:0006355| regulation of transcription, DNA-dependent CCND1;RARG GO:0010628| positive regulation of gene expression BRAF;RARG GO:0060070| canonical Wnt receptor signaling pathway CCND1;RARG GO:0043066| negative regulation of apoptotic process RARG;BRAF GO:0006367| transcription initiation from RNA polymerase II promoter CCND1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter CCND1;RARG GO:0006351| transcription, DNA-dependent CCND1;RARG 940:[DB02466 DB01235] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2;DRD3 GO:0008284| positive regulation of cell proliferation RARG;DRD3 GO:0010628| positive regulation of gene expression DRD1;RARG 941:[DB02466 DB02709] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation APP;PTGS2;PPARG;CYP1B1;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2;PPARG;ESR1;PPARA;NR1I3 GO:0006351| transcription, DNA-dependent RARG;KHSRP;NR1I2;PPARG;PPARA;ESR1;AHR;NR1I3;CSNK2A1 GO:0031641| regulation of myelination RARG;AKT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter SNCA;RARG;APP;PPARG;PPARA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARG;NR1I3;NR1I2;ESR1;PPARA;PPARG GO:0010468| regulation of gene expression RARG;PPARA;APP;AHR;CYP1A2 GO:0032526| response to retinoic acid RARG;PPARG GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0010628| positive regulation of gene expression RARG;NR1I2;APP GO:0043010| camera-type eye development CYP1A1;RARG GO:0043066| negative regulation of apoptotic process PTGS2;AKT1;SNCA;ALB;RARG GO:0043065| positive regulation of apoptotic process CYP1B1;RARG;SNCA;AKT1;APP;PTGS2;PPARG GO:0006355| regulation of transcription, DNA-dependent NR1I3;AHR;CSNK2A1;NR1I2;PPARG;ESR1;PPARA;KHSRP;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;AKT1;APP;AHR;NR1I2;PPARG;ESR1;PPARA;RARG GO:0008284| positive regulation of cell proliferation AKT1;CSNK2A1;PTGS2;RARG 942:[DB02466 DB00590] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00590|Doxazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;CYP2C19;CYP2D6;CYP3A4;ORM1;ABCB1;SLC22A1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;ADRA1D GO:0008285| negative regulation of cell proliferation RARG;ADRA1A 943:[DB02466 DB00333] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00333|Methadone OPRM1;GRIN3A;CHRNA10;OPRD1;HTR3A;LY96;ORM2;CYP3A4;CYP2C19;CYP3A5;CYP3A7;CYP2D6;CYP2B6;CYP2C8;CYP19A1;CYP1A2;CYP2C18;CYP2C9;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0008285| negative regulation of cell proliferation RARG;OPRM1 944:[DB02466 DB01348] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways 945:[DB02466 DB09054] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways 946:[DB02466 DB01565] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter POMC;RARG 947:[DB02466 DB14575] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways 948:[DB02466 DB01601] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01601|Lopinavir pol;CYP3A4;CYP2D6;CYP2C19;CYP2B6;CYP2C9;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways 949:[DB02466 DB00327] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 950:[DB02466 DB08439] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0060349| bone morphogenesis RARG;LTF GO:0006351| transcription, DNA-dependent LTF;RARG GO:0008285| negative regulation of cell proliferation PTGS2;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;LTF GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;RARG;LTF 951:[DB02466 DB02703] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways 952:[DB02466 DB00518] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 953:[DB02466 DB00268] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0010628| positive regulation of gene expression DRD1;RARG GO:0043066| negative regulation of apoptotic process RARG;HTR2B GO:0008284| positive regulation of cell proliferation DRD3;HTR2A;HTR1A;RARG;ADRA2A;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;RARG GO:0008285| negative regulation of cell proliferation DRD2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 954:[DB02466 DB01196] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;RARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARG;ESR2 GO:0006351| transcription, DNA-dependent ESR1;ESR2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR2;RARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;RARG 955:[DB02466 DB06263] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;RARG GO:0043066| negative regulation of apoptotic process RARG;POR 956:[DB02466 DB00186] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;TSPO 957:[DB02466 DB00426] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways 958:[DB02466 DB00753] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 959:[DB02466 DB01140] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways 960:[DB02466 DB12161] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 961:[DB02466 DB08909] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways 962:[DB02466 DB01201] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways 963:[DB02466 DB00688] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00688|Mycophenolate mofetil IMPDH1;IMPDH2;UGT1A1;UGT1A7;UGT1A6;UGT1A9;UGT2B7;UGT1A8;UGT1A10;CES1;CES2;CYP3A4;CYP3A5;CYP2C8;ALB;SLCO1B1;SLCO1B3;ABCC2;ABCG2;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0060041| retina development in camera-type eye RARG;IMPDH2 964:[DB02466 DB00747] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;RARG 965:[DB02466 DB04855] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0043010| camera-type eye development CACNA1C;RARG GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0008284| positive regulation of cell proliferation ADRA2A;RARG;ADRA1D 966:[DB02466 DB00343] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00343|Diltiazem CACNG1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2D6;CYP2C8;ABCB1 common genes common pathways 967:[DB02466 DB00844] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;OPRM1 968:[DB02466 DB00624] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00624|Testosterone AR;ESR1;NR3C2;CYP3A5;CYP19A1;CYP11A1;MAOA;CYP3A7;CYP3A4;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR;NR3C2;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG;AR GO:0010468| regulation of gene expression RARG;AR GO:0048608| reproductive structure development RARG;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C2;AR;RARG GO:0008285| negative regulation of cell proliferation CYP1B1;AR;RARG GO:0006351| transcription, DNA-dependent ESR1;RARG;AR;NR3C2 GO:0060740| prostate gland epithelium morphogenesis AR;RARG GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0008284| positive regulation of cell proliferation AR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;RARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent RARG;AR;NR3C2;ESR1 GO:0010628| positive regulation of gene expression RARG;AR GO:0043066| negative regulation of apoptotic process ALB;RARG GO:0035264| multicellular organism growth AR;RARG GO:0043010| camera-type eye development CYP1A1;RARG 969:[DB02466 DB00934] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0008284| positive regulation of cell proliferation ADRA1D;HTR2A;CHRM1;RARG;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;DRD2 970:[DB02466 DB11386] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11386|Chlorobutanol KCNH2 common genes common pathways 971:[DB02466 DB14003] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent SEC14L2;RARG GO:0010628| positive regulation of gene expression RARG;LDLR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;VLDLR GO:0006351| transcription, DNA-dependent RARG;SEC14L2 972:[DB02466 DB09128] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;RARG 973:[DB02466 DB11642] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;RARG 974:[DB02466 DB07177] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 975:[DB02466 DB03793] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;PRDX5 976:[DB02466 DB02925] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB02925|Piretanide SLC12A1 common genes common pathways 977:[DB02466 DB00603] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway RARG;PGR;ESR1 GO:0006351| transcription, DNA-dependent ESR1;RARG;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARG GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PGR;RARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RARG;ESR1 978:[DB02466 DB06480] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 979:[DB02466 DB00472] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00472|Fluoxetine SLC6A4;KCNH2;HTR2C;CKS1B;CHRNA2;CHRNA3;CHRNB4;CYP2C19;CYP2D6;CYP2C9;CYP2B;CYP1A2;CYP3A4;CYP2B6;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process RARG;ALB GO:0010628| positive regulation of gene expression RARG;SLC6A4 GO:0071300| cellular response to retinoic acid RARG;SLC6A4 GO:0006355| regulation of transcription, DNA-dependent CKS1B;RARG 980:[DB02466 DB01250] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01250|Olsalazine TPMT;IFNG common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;RARG GO:0008284| positive regulation of cell proliferation IFNG;RARG GO:0010628| positive regulation of gene expression RARG;IFNG 981:[DB02466 DB00881] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways 982:[DB02466 DB06403] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0043066| negative regulation of apoptotic process EDNRB;RARG GO:0008284| positive regulation of cell proliferation EDNRB;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;EDNRB 983:[DB02466 DB01333] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways 984:[DB02466 DB01339] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways 985:[DB02466 DB13857] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PGR;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RARG GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RARG GO:0006351| transcription, DNA-dependent PGR;RARG GO:0043401| steroid hormone mediated signaling pathway PGR;RARG 986:[DB02466 DB00909] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00909|Zonisamide SCN1A;SCN2A;SCN3A;SCN4A;SCN5A;SCN9A;SCN11A;SCN1B;SCN2B;SCN3B;SCN4B;CACNA1G;CACNA1H;CACNA1I;CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA8;CA9;CA10;CA11;CA12;CA13;CA14;MAOB;MAOA;CYP3A4;AOX1;CYP2C19;UGT1A1;CYP3A5 common genes common pathways 987:[DB02466 DB00222] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways 988:[DB02466 DB00721] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;RARG GO:0043065| positive regulation of apoptotic process KCNMA1;RARG 989:[DB02466 DB00273] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00273|Topiramate GABRA1;SCN1A;GRIK1;CA2;CA4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CA1;CA3;CYP2C19;CYP3A4 common genes common pathways 990:[DB02466 DB14507] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;GSK3B GO:0060070| canonical Wnt receptor signaling pathway RARG;GSK3B GO:0010628| positive regulation of gene expression GSK3B;RARG 991:[DB02466 DB00996] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ADORA1 GO:0043065| positive regulation of apoptotic process GRIN1;RARG;GRIN2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;GRIN1 GO:0008285| negative regulation of cell proliferation ADORA1;RARG 992:[DB02466 DB06637] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways 993:[DB02466 DB06207] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;ADRA1A GO:0008284| positive regulation of cell proliferation ADRA1D;RARG 994:[DB02466 DB01259] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;ERBB2 GO:0008284| positive regulation of cell proliferation RARG;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;RARG GO:0010628| positive regulation of gene expression ERBB2;RARG GO:0043066| negative regulation of apoptotic process EGFR;RARG GO:0006351| transcription, DNA-dependent RARG;ERBB2 995:[DB02466 DB01406] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0006351| transcription, DNA-dependent PGR;RARG;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PGR;AR;RARG GO:0008285| negative regulation of cell proliferation AR;RARG GO:0010468| regulation of gene expression AR;RARG GO:0048608| reproductive structure development RARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARG;AR;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR;RARG GO:0035264| multicellular organism growth RARG;AR GO:0010628| positive regulation of gene expression RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PGR;RARG;AR GO:0008284| positive regulation of cell proliferation AR;RARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PGR;AR;RARG GO:0060740| prostate gland epithelium morphogenesis RARG;AR 996:[DB02466 DB00862] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways 997:[DB02466 DB01215] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways 998:[DB02466 DB00448] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;CYP1B1 GO:0043065| positive regulation of apoptotic process CYP1B1;RARG GO:0043010| camera-type eye development RARG;CYP1A1 999:[DB02466 DB01181] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways GO:0006351| transcription, DNA-dependent NR1I2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RARG GO:0010628| positive regulation of gene expression RARG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent RARG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RARG 1000:[DB02466 DB13170] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB13170|Plecanatide GUCY1A2 common genes common pathways 1001:[DB02466 DB01073] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0060041| retina development in camera-type eye RRM1;RARG 1002:[DB02466 DB00436] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;KCNMA1 1003:[DB02466 DB00484] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;ADRA2A 1004:[DB02466 DB05207] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TNF GO:0010628| positive regulation of gene expression RARG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;RARG GO:0043068| positive regulation of programmed cell death TNF;RARG GO:0043065| positive regulation of apoptotic process RARG;TNF 1005:[DB02466 DB11737] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;EGFR GO:0008284| positive regulation of cell proliferation RARG;EGFR GO:0010468| regulation of gene expression CYP1A2;RARG 1006:[DB02466 DB01225] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways GO:0043066| negative regulation of apoptotic process MPO;RARG 1007:[DB02466 DB01020] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways 1008:[DB02466 DB01065] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0043065| positive regulation of apoptotic process CYP1B1;RARG;IDO1 GO:0008284| positive regulation of cell proliferation RARG;CALR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;RORB;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CALR;RORB;RARG GO:0010628| positive regulation of gene expression CALR;RARG GO:0071300| cellular response to retinoic acid RARG;RORB GO:0043066| negative regulation of apoptotic process MPO;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARG;RORB GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CALR;RARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway RARG;RORB;ESR1 GO:0060041| retina development in camera-type eye RARG;RORB GO:0008285| negative regulation of cell proliferation RARG;CYP1B1 GO:0006351| transcription, DNA-dependent RARG;RORB;ESR1 1009:[DB02466 DB06681] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB06681|Belatacept CD86;CD80 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;RARG 1010:[DB02466 DB01535] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;RARG 1011:[DB02466 DB00679] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0010628| positive regulation of gene expression DRD1;RARG GO:0008284| positive regulation of cell proliferation HTR2A;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RARG GO:0008285| negative regulation of cell proliferation RARG;ADRA1A;DRD2 1012:[DB02466 DB00280] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CHRM1 GO:0010468| regulation of gene expression CYP1A2;RARG 1013:[DB02466 DB01381] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways 1014:[DB02466 DB01208] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;RARG GO:0043065| positive regulation of apoptotic process TOP2A;RARG 1015:[DB02466 DB01166] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043066| negative regulation of apoptotic process PDE3A;RARG 1016:[DB02466 DB05311] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB05311|Ecallantide KLKB1 common genes common pathways 1017:[DB02466 DB01241] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PPARA;RARG GO:0006351| transcription, DNA-dependent RARG;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARA GO:0010468| regulation of gene expression RARG;CYP1A2;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARA 1018:[DB02466 DB00778] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways 1019:[DB02466 DB00181] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways 1020:[DB02466 DB04839] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0010628| positive regulation of gene expression AR;RARG GO:0035264| multicellular organism growth RARG;AR GO:0060740| prostate gland epithelium morphogenesis RARG;AR GO:0006355| regulation of transcription, DNA-dependent RARG;AR GO:0008284| positive regulation of cell proliferation RARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;RARG GO:0008285| negative regulation of cell proliferation AR;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;AR GO:0006351| transcription, DNA-dependent AR;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter RARG;AR GO:0048608| reproductive structure development AR;RARG GO:0010468| regulation of gene expression AR;RARG 1021:[DB02466 DB01276] DB02466|4-[3-Oxo-3-(5,5,8,8-Tetramethyl-5,6,7,8-Tetrahydro-Naphthalen-2-Yl)-Propenyl]-Benzoic Acid RARG DB01276|Exenatide GLP1R;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 1022:[DB09245 DB07543] DB09245|Toloxatone MAOA;MAOA DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways 1023:[DB09245 DB11730] DB09245|Toloxatone MAOA;MAOA DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1024:[DB09245 DB03685] DB09245|Toloxatone MAOA;MAOA DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways 1025:[DB09245 DB01179] DB09245|Toloxatone MAOA;MAOA DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways 1026:[DB09245 DB05127] DB09245|Toloxatone MAOA;MAOA DB05127|ANA971 TLR7 common genes common pathways 1027:[DB09245 DB03372] DB09245|Toloxatone MAOA;MAOA DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways 1028:[DB09245 DB04863] DB09245|Toloxatone MAOA;MAOA DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways 1029:[DB09245 DB00725] DB09245|Toloxatone MAOA;MAOA DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways 1030:[DB09245 DB00838] DB09245|Toloxatone MAOA;MAOA DB00838|Clocortolone NR3C1 common genes common pathways 1031:[DB09245 DB06935] DB09245|Toloxatone MAOA;MAOA DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways 1032:[DB09245 DB02789] DB09245|Toloxatone MAOA;MAOA DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1033:[DB09245 DB00087] DB09245|Toloxatone MAOA;MAOA DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 1034:[DB09245 DB06803] DB09245|Toloxatone MAOA;MAOA DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2C9 1035:[DB09245 DB06914] DB09245|Toloxatone MAOA;MAOA DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;MAOA 1036:[DB09245 DB00175] DB09245|Toloxatone MAOA;MAOA DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process HMGCR;MAOA;CYP2C8 1037:[DB09245 DB00940] DB09245|Toloxatone MAOA;MAOA DB00940|Methantheline CHRM1;HRH2 common genes common pathways 1038:[DB09245 DB01837] DB09245|Toloxatone MAOA;MAOA DB01837|O-acetyl-L-serine PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1 1039:[DB09245 DB09422] DB09245|Toloxatone MAOA;MAOA DB09422|Soybean oil PPARA common genes common pathways 1040:[DB09245 DB00098] DB09245|Toloxatone MAOA;MAOA DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways 1041:[DB09245 DB03245] DB09245|Toloxatone MAOA;MAOA DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways GO:0055114| oxidation-reduction process MAOA;GCDH 1042:[DB09245 DB04185] DB09245|Toloxatone MAOA;MAOA DB04185|Norvaline OTC;GATM common genes common pathways 1043:[DB09245 DB01165] DB09245|Toloxatone MAOA;MAOA DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 1044:[DB09245 DB00671] DB09245|Toloxatone MAOA;MAOA DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 1045:[DB09245 DB06685] DB09245|Toloxatone MAOA;MAOA DB06685|Laquinimod CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1046:[DB09245 DB01959] DB09245|Toloxatone MAOA;MAOA DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways 1047:[DB09245 DB07546] DB09245|Toloxatone MAOA;MAOA DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways 1048:[DB09245 DB05111] DB09245|Toloxatone MAOA;MAOA DB05111|Fontolizumab IFNG common genes common pathways 1049:[DB09245 DB03600] DB09245|Toloxatone MAOA;MAOA DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes common pathways 1050:[DB09245 DB01436] DB09245|Toloxatone MAOA;MAOA DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP27B1 1051:[DB09245 DB08256] DB09245|Toloxatone MAOA;MAOA DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways 1052:[DB09245 DB06233] DB09245|Toloxatone MAOA;MAOA DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1053:[DB09245 DB07830] DB09245|Toloxatone MAOA;MAOA DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways 1054:[DB09245 DB00987] DB09245|Toloxatone MAOA;MAOA DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1055:[DB09245 DB12450] DB09245|Toloxatone MAOA;MAOA DB12450|Propyl Gallate ESR1 common genes common pathways 1056:[DB09245 DB05258] DB09245|Toloxatone MAOA;MAOA DB05258|Natural alpha interferon IFNAR1 common genes common pathways 1057:[DB09245 DB08864] DB09245|Toloxatone MAOA;MAOA DB08864|Rilpivirine pol;NR1I2;CYP3A4;CYP2C19;CYP2B6;CYP2D6;ALB;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;MAOA;CYP2C19;CYP2D6 1058:[DB09245 DB08936] DB09245|Toloxatone MAOA;MAOA DB08936|Chlorcyclizine HRH1 common genes common pathways 1059:[DB09245 DB09160] DB09245|Toloxatone MAOA;MAOA DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways 1060:[DB09245 DB12872] DB09245|Toloxatone MAOA;MAOA DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0055114| oxidation-reduction process F8;MAOA 1061:[DB09245 DB09371] DB09245|Toloxatone MAOA;MAOA DB09371|Norethynodrel ESR1;AR;SHBG;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1062:[DB09245 DB00135] DB09245|Toloxatone MAOA;MAOA DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process TH;MAOA 1063:[DB09245 DB02340] DB09245|Toloxatone MAOA;MAOA DB02340|N-Acetyl-Serine F13A1 common genes common pathways 1064:[DB09245 DB06477] DB09245|Toloxatone MAOA;MAOA DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways 1065:[DB09245 DB02483] DB09245|Toloxatone MAOA;MAOA DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;LDHA 1066:[DB09245 DB07092] DB09245|Toloxatone MAOA;MAOA DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways 1067:[DB09245 DB11641] DB09245|Toloxatone MAOA;MAOA DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1068:[DB09245 DB00654] DB09245|Toloxatone MAOA;MAOA DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways 1069:[DB09245 DB01211] DB09245|Toloxatone MAOA;MAOA DB01211|Clarithromycin rplJ;KCNH2;SLCO1B1;SLCO1B3;CYP3A4;CYP3A5;CYP2C19;CYP3A7;SLC22A7;ABCB1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A5;MAOA;CYP3A7;CYP3A4 1070:[DB09245 DB04363] DB09245|Toloxatone MAOA;MAOA DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways GO:0055114| oxidation-reduction process BLVRB;MAOA 1071:[DB09245 DB01218] DB09245|Toloxatone MAOA;MAOA DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP3A5;CYP2C8;CYP2D6 1072:[DB09245 DB01099] DB09245|Toloxatone MAOA;MAOA DB01099|Flucytosine DNMT1 common genes common pathways 1073:[DB09245 DB02857] DB09245|Toloxatone MAOA;MAOA DB02857|Guanosine PNP common genes common pathways 1074:[DB09245 DB01204] DB09245|Toloxatone MAOA;MAOA DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;MAOA;CYP1B1 1075:[DB09245 DB06267] DB09245|Toloxatone MAOA;MAOA DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP3A5 1076:[DB09245 DB09090] DB09245|Toloxatone MAOA;MAOA DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1077:[DB09245 DB12836] DB09245|Toloxatone MAOA;MAOA DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways 1078:[DB09245 DB00139] DB09245|Toloxatone MAOA;MAOA DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ALDH5A1 GO:0055114| oxidation-reduction process PLOD3;BBOX1;SDHB;ALDH5A1;P3H1;P4HA1;HSD17B6;ASPH;P3H3;SDHC;SDHA;SDHD;TMLHE;P4HA2;MAOA;P3H2;PLOD1 1079:[DB09245 DB02110] DB09245|Toloxatone MAOA;MAOA DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways GO:0055114| oxidation-reduction process CYCS;MAOA;PTGS1 1080:[DB09245 DB01854] DB09245|Toloxatone MAOA;MAOA DB01854|5-Bromonicotinamide ART1 common genes common pathways 1081:[DB09245 DB06156] DB09245|Toloxatone MAOA;MAOA DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0042420| dopamine catabolic process MAOA;SLC6A3 1082:[DB09245 DB01430] DB09245|Toloxatone MAOA;MAOA DB01430|Almitrine ATP1A1 common genes common pathways 1083:[DB09245 DB13164] DB09245|Toloxatone MAOA;MAOA DB13164|Olmutinib EGFR common genes common pathways 1084:[DB09245 DB09334] DB09245|Toloxatone MAOA;MAOA DB09334|Seractide acetate MC2R common genes common pathways 1085:[DB09245 DB03752] DB09245|Toloxatone MAOA;MAOA DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;MAOA 1086:[DB09245 DB04614] DB09245|Toloxatone MAOA;MAOA DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 1087:[DB09245 DB08695] DB09245|Toloxatone MAOA;MAOA DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways 1088:[DB09245 DB05785] DB09245|Toloxatone MAOA;MAOA DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways 1089:[DB09245 DB00119] DB09245|Toloxatone MAOA;MAOA DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0042135| neurotransmitter catabolic process ABAT;MAOA GO:0055114| oxidation-reduction process MAOA;PDHB 1090:[DB09245 DB02623] DB09245|Toloxatone MAOA;MAOA DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways 1091:[DB09245 DB01805] DB09245|Toloxatone MAOA;MAOA DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 1092:[DB09245 DB01232] DB09245|Toloxatone MAOA;MAOA DB01232|Saquinavir pol;CYP3A7;CYP3A5;CYP3A4;CYP11A1;CYP2C8;CYP2D6;ORM1;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;ABCC1;ABCC2;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP11A1;CYP3A4;CYP3A7;MAOA;CYP2D6;CYP2C8;CYP3A5 1093:[DB09245 DB11201] DB09245|Toloxatone MAOA;MAOA DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;PTGS2;MAOA 1094:[DB09245 DB02418] DB09245|Toloxatone MAOA;MAOA DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways 1095:[DB09245 DB00392] DB09245|Toloxatone MAOA;MAOA DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways 1096:[DB09245 DB08632] DB09245|Toloxatone MAOA;MAOA DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways 1097:[DB09245 DB09559] DB09245|Toloxatone MAOA;MAOA DB09559|Necitumumab EGFR common genes common pathways 1098:[DB09245 DB07297] DB09245|Toloxatone MAOA;MAOA DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways 1099:[DB09245 DB01914] DB09245|Toloxatone MAOA;MAOA DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways 1100:[DB09245 DB04005] DB09245|Toloxatone MAOA;MAOA DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways 1101:[DB09245 DB00149] DB09245|Toloxatone MAOA;MAOA DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways 1102:[DB09245 DB08251] DB09245|Toloxatone MAOA;MAOA DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways 1103:[DB09245 DB01917] DB09245|Toloxatone MAOA;MAOA DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways 1104:[DB09245 DB14568] DB09245|Toloxatone MAOA;MAOA DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;IDH1;CYP3A4;CYP2B6;MAOA;CYP2C8 1105:[DB09245 DB03256] DB09245|Toloxatone MAOA;MAOA DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways 1106:[DB09245 DB08486] DB09245|Toloxatone MAOA;MAOA DB08486|Efaproxiral HBA1;HBB common genes common pathways 1107:[DB09245 DB08302] DB09245|Toloxatone MAOA;MAOA DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways 1108:[DB09245 DB07842] DB09245|Toloxatone MAOA;MAOA DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways 1109:[DB09245 DB05308] DB09245|Toloxatone MAOA;MAOA DB05308|ANX-510 TYMS common genes common pathways 1110:[DB09245 DB07302] DB09245|Toloxatone MAOA;MAOA DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways 1111:[DB09245 DB02166] DB09245|Toloxatone MAOA;MAOA DB02166|Propidium ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 1112:[DB09245 DB14597] DB09245|Toloxatone MAOA;MAOA DB14597|Lanadelumab KLKB1 common genes common pathways 1113:[DB09245 DB07047] DB09245|Toloxatone MAOA;MAOA DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways 1114:[DB09245 DB09517] DB09245|Toloxatone MAOA;MAOA DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways 1115:[DB09245 DB07144] DB09245|Toloxatone MAOA;MAOA DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 1116:[DB09245 DB06739] DB09245|Toloxatone MAOA;MAOA DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYP2C19;CYP2C8;MAOA;CYP2B6;CYP2A6;CYP2C9;CYP3A4 1117:[DB09245 DB07670] DB09245|Toloxatone MAOA;MAOA DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C18 1118:[DB09245 DB01087] DB09245|Toloxatone MAOA;MAOA DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process NQO2;CYP1A2;MAOA;CYP3A4;CYP1A1;CYP1B1;CYP2D6 1119:[DB09245 DB06247] DB09245|Toloxatone MAOA;MAOA DB06247|CX516 GRIA1 common genes common pathways 1120:[DB09245 DB07740] DB09245|Toloxatone MAOA;MAOA DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways 1121:[DB09245 DB02404] DB09245|Toloxatone MAOA;MAOA DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 1122:[DB09245 DB11753] DB09245|Toloxatone MAOA;MAOA DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;MAOA;CYP1A2;CYP2B6;CYP3A4;CYP2C9 1123:[DB09245 DB04469] DB09245|Toloxatone MAOA;MAOA DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 1124:[DB09245 DB06530] DB09245|Toloxatone MAOA;MAOA DB06530|Resiquimod TLR7;TLR8 common genes common pathways 1125:[DB09245 DB06607] DB09245|Toloxatone MAOA;MAOA DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways 1126:[DB09245 DB00997] DB09245|Toloxatone MAOA;MAOA DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CBR3;POR;CYP1B1;NDUFS2;NOS3;NDUFS7;CYP2D6;CBR1;AKR1C3;XDH;MAOA;NOS2;CYP2B6;NDUFS3;AKR1A1;CYP3A4;NQO1;NOS1 1127:[DB09245 DB04801] DB09245|Toloxatone MAOA;MAOA DB04801|cis-Vaccenic acid PPARD common genes common pathways 1128:[DB09245 DB09421] DB09245|Toloxatone MAOA;MAOA DB09421|Protirelin TRHR common genes common pathways 1129:[DB09245 DB07282] DB09245|Toloxatone MAOA;MAOA DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways 1130:[DB09245 DB02427] DB09245|Toloxatone MAOA;MAOA DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 1131:[DB09245 DB00168] DB09245|Toloxatone MAOA;MAOA DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 1132:[DB09245 DB12307] DB09245|Toloxatone MAOA;MAOA DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP3A5;CYP3A7;MAOA;CYP3A4 1133:[DB09245 DB12436] DB09245|Toloxatone MAOA;MAOA DB12436|Vofopitant TACR1 common genes common pathways 1134:[DB09245 DB04105] DB09245|Toloxatone MAOA;MAOA DB04105|N-Heptylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process MAOA;ADH1B 1135:[DB09245 DB05407] DB09245|Toloxatone MAOA;MAOA DB05407|TBC-3711 EDN1 common genes common pathways 1136:[DB09245 DB12555] DB09245|Toloxatone MAOA;MAOA DB12555|Nelotanserin HTR2A common genes common pathways 1137:[DB09245 DB06469] DB09245|Toloxatone MAOA;MAOA DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1138:[DB09245 DB08655] DB09245|Toloxatone MAOA;MAOA DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways 1139:[DB09245 DB02360] DB09245|Toloxatone MAOA;MAOA DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways 1140:[DB09245 DB07053] DB09245|Toloxatone MAOA;MAOA DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways 1141:[DB09245 DB14583] DB09245|Toloxatone MAOA;MAOA DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1142:[DB09245 DB08867] DB09245|Toloxatone MAOA;MAOA DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP3A4 1143:[DB09245 DB04942] DB09245|Toloxatone MAOA;MAOA DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways 1144:[DB09245 DB04725] DB09245|Toloxatone MAOA;MAOA DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ALOX5;CYP2C9;CYP2J2;MAOA;PTGS2 1145:[DB09245 DB00153] DB09245|Toloxatone MAOA;MAOA DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0055114| oxidation-reduction process CYP27B1;CYP2R1;MAOA;CYP27A1;CYP3A4;CYP24A1 1146:[DB09245 DB00358] DB09245|Toloxatone MAOA;MAOA DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE GO:0055114| oxidation-reduction process CYP2D6;CYP19A1;CYP3A4;MAOA 1147:[DB09245 DB00735] DB09245|Toloxatone MAOA;MAOA DB00735|Naftifine SQLE common genes common pathways GO:0055114| oxidation-reduction process SQLE;MAOA 1148:[DB09245 DB00770] DB09245|Toloxatone MAOA;MAOA DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;ABCC4 1149:[DB09245 DB05956] DB09245|Toloxatone MAOA;MAOA DB05956|EVT-101 RXRA;GRIN2B common genes common pathways 1150:[DB09245 DB04967] DB09245|Toloxatone MAOA;MAOA DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0055114| oxidation-reduction process APEX1;MAOA 1151:[DB09245 DB07422] DB09245|Toloxatone MAOA;MAOA DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways 1152:[DB09245 DB09229] DB09245|Toloxatone MAOA;MAOA DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1153:[DB09245 DB06094] DB09245|Toloxatone MAOA;MAOA DB06094|Apatorsen HSPB1 common genes common pathways 1154:[DB09245 DB09078] DB09245|Toloxatone MAOA;MAOA DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2C9;CYP3A4;CYP2B6;AOX1;CYP2C8;CYP2C19;CYP2D6 1155:[DB09245 DB04974] DB09245|Toloxatone MAOA;MAOA DB04974|AP1903 MTOR common genes common pathways 1156:[DB09245 DB00417] DB09245|Toloxatone MAOA;MAOA DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 1157:[DB09245 DB04471] DB09245|Toloxatone MAOA;MAOA DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways 1158:[DB09245 DB06885] DB09245|Toloxatone MAOA;MAOA DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways 1159:[DB09245 DB02263] DB09245|Toloxatone MAOA;MAOA DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways 1160:[DB09245 DB06311] DB09245|Toloxatone MAOA;MAOA DB06311|Darapladib PLA2G4A common genes common pathways 1161:[DB09245 DB02696] DB09245|Toloxatone MAOA;MAOA DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways 1162:[DB09245 DB08121] DB09245|Toloxatone MAOA;MAOA DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways 1163:[DB09245 DB03192] DB09245|Toloxatone MAOA;MAOA DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways GO:0055114| oxidation-reduction process HSD17B4;MAOA 1164:[DB09245 DB14515] DB09245|Toloxatone MAOA;MAOA DB14515|Magnesium lactate ATP1A1 common genes common pathways 1165:[DB09245 DB03267] DB09245|Toloxatone MAOA;MAOA DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 1166:[DB09245 DB00701] DB09245|Toloxatone MAOA;MAOA DB00701|Amprenavir pol;CYP3A4;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A5;ABCB1;ABCC1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP3A4;MAOA;CYP2C8;CYP2C19;CYP2D6;CYP3A5 1167:[DB09245 DB12569] DB09245|Toloxatone MAOA;MAOA DB12569|Tonapofylline ADORA1 common genes common pathways 1168:[DB09245 DB00882] DB09245|Toloxatone MAOA;MAOA DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP19A1;CYP2E1;CYP1A1;CYP11A1 1169:[DB09245 DB07234] DB09245|Toloxatone MAOA;MAOA DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways 1170:[DB09245 DB01248] DB09245|Toloxatone MAOA;MAOA DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;MAOA;CYP3A5;CYP1B1 1171:[DB09245 DB05284] DB09245|Toloxatone MAOA;MAOA DB05284|CA4P TUBB common genes common pathways 1172:[DB09245 DB08498] DB09245|Toloxatone MAOA;MAOA DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways 1173:[DB09245 DB01969] DB09245|Toloxatone MAOA;MAOA DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 1174:[DB09245 DB00172] DB09245|Toloxatone MAOA;MAOA DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process PRODH;P3H1;P4HA1;PYCR1;P3H2;MAOA;PYCR2;P4HA2;P3H3 1175:[DB09245 DB01989] DB09245|Toloxatone MAOA;MAOA DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways 1176:[DB09245 DB00269] DB09245|Toloxatone MAOA;MAOA DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1 1177:[DB09245 DB02419] DB09245|Toloxatone MAOA;MAOA DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways 1178:[DB09245 DB12128] DB09245|Toloxatone MAOA;MAOA DB12128|Ulimorelin GHSR common genes common pathways 1179:[DB09245 DB07405] DB09245|Toloxatone MAOA;MAOA DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 1180:[DB09245 DB00711] DB09245|Toloxatone MAOA;MAOA DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1;ALOX5 1181:[DB09245 DB05420] DB09245|Toloxatone MAOA;MAOA DB05420|Gallium maltolate RRM1 common genes common pathways GO:0055114| oxidation-reduction process RRM1;MAOA 1182:[DB09245 DB08903] DB09245|Toloxatone MAOA;MAOA DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1183:[DB09245 DB03187] DB09245|Toloxatone MAOA;MAOA DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 1184:[DB09245 DB01058] DB09245|Toloxatone MAOA;MAOA DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP3A7;CYP3A4;CYP3A43;CYP3A5;CYP2C19 1185:[DB09245 DB05798] DB09245|Toloxatone MAOA;MAOA DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways 1186:[DB09245 DB07733] DB09245|Toloxatone MAOA;MAOA DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways 1187:[DB09245 DB14012] DB09245|Toloxatone MAOA;MAOA DB14012|Burosumab FGF23 common genes common pathways 1188:[DB09245 DB07978] DB09245|Toloxatone MAOA;MAOA DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 1189:[DB09245 DB08735] DB09245|Toloxatone MAOA;MAOA DB08735|R,S-Warfarin alcohol ALB common genes common pathways 1190:[DB09245 DB00332] DB09245|Toloxatone MAOA;MAOA DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6 1191:[DB09245 DB05025] DB09245|Toloxatone MAOA;MAOA DB05025|Arimoclomol SOD1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;SOD1 1192:[DB09245 DB06245] DB09245|Toloxatone MAOA;MAOA DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways 1193:[DB09245 DB06780] DB09245|Toloxatone MAOA;MAOA DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1194:[DB09245 DB05424] DB09245|Toloxatone MAOA;MAOA DB05424|Canertinib EGFR common genes common pathways 1195:[DB09245 DB05219] DB09245|Toloxatone MAOA;MAOA DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP2B6;CYP2C9 1196:[DB09245 DB00890] DB09245|Toloxatone MAOA;MAOA DB00890|Dienestrol ESR1;SHBG common genes common pathways 1197:[DB09245 DB05469] DB09245|Toloxatone MAOA;MAOA DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways 1198:[DB09245 DB02750] DB09245|Toloxatone MAOA;MAOA DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 1199:[DB09245 DB11638] DB09245|Toloxatone MAOA;MAOA DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process G6PD;LDHB;PRDX1;CYP2D6;ALDH7A1;CYP2C19;FTO;MDH1;P4HB;MAOA;LDHA;GAPDHS;CYCS;GAPDH 1200:[DB09245 DB01161] DB09245|Toloxatone MAOA;MAOA DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0042420| dopamine catabolic process SLC6A3;MAOA 1201:[DB09245 DB07374] DB09245|Toloxatone MAOA;MAOA DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways 1202:[DB09245 DB04882] DB09245|Toloxatone MAOA;MAOA DB04882|Edotecarin TOP1 common genes common pathways 1203:[DB09245 DB14637] DB09245|Toloxatone MAOA;MAOA DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1204:[DB09245 DB06451] DB09245|Toloxatone MAOA;MAOA DB06451|Aprinocarsen PRKCA common genes common pathways 1205:[DB09245 DB07207] DB09245|Toloxatone MAOA;MAOA DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways 1206:[DB09245 DB00663] DB09245|Toloxatone MAOA;MAOA DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1207:[DB09245 DB02715] DB09245|Toloxatone MAOA;MAOA DB02715|Compound 18 ESR1 common genes common pathways 1208:[DB09245 DB01373] DB09245|Toloxatone MAOA;MAOA DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0055114| oxidation-reduction process AOC1;MAOA;CP 1209:[DB09245 DB01321] DB09245|Toloxatone MAOA;MAOA DB01321|Josamycin rplD;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1210:[DB09245 DB08361] DB09245|Toloxatone MAOA;MAOA DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways 1211:[DB09245 DB07159] DB09245|Toloxatone MAOA;MAOA DB07159|Tamatinib SYK common genes common pathways 1212:[DB09245 DB00114] DB09245|Toloxatone MAOA;MAOA DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0055114| oxidation-reduction process PNPO;CBS;MAOA;GLDC GO:0042135| neurotransmitter catabolic process MAOA;ABAT 1213:[DB09245 DB02931] DB09245|Toloxatone MAOA;MAOA DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways 1214:[DB09245 DB05513] DB09245|Toloxatone MAOA;MAOA DB05513|Atiprimod IL6;TNF common genes common pathways 1215:[DB09245 DB11091] DB09245|Toloxatone MAOA;MAOA DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;GPX1;CAT 1216:[DB09245 DB13179] DB09245|Toloxatone MAOA;MAOA DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;MAOA;CYP3A7;CYP2C18;CYP2C8;CYP3A5;CYP3A43 1217:[DB09245 DB13153] DB09245|Toloxatone MAOA;MAOA DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways 1218:[DB09245 DB03193] DB09245|Toloxatone MAOA;MAOA DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes common pathways 1219:[DB09245 DB11569] DB09245|Toloxatone MAOA;MAOA DB11569|Ixekizumab IL17A common genes common pathways 1220:[DB09245 DB06345] DB09245|Toloxatone MAOA;MAOA DB06345|AR-9281 EPHX2 common genes common pathways 1221:[DB09245 DB01130] DB09245|Toloxatone MAOA;MAOA DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1222:[DB09245 DB06151] DB09245|Toloxatone MAOA;MAOA DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways 1223:[DB09245 DB03704] DB09245|Toloxatone MAOA;MAOA DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0055114| oxidation-reduction process ADH5;MAOA 1224:[DB09245 DB06634] DB09245|Toloxatone MAOA;MAOA DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1225:[DB09245 DB05024] DB09245|Toloxatone MAOA;MAOA DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;MAOA 1226:[DB09245 DB00400] DB09245|Toloxatone MAOA;MAOA DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;MAOA;CYP1A2 1227:[DB09245 DB07465] DB09245|Toloxatone MAOA;MAOA DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways 1228:[DB09245 DB05869] DB09245|Toloxatone MAOA;MAOA DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways 1229:[DB09245 DB01629] DB09245|Toloxatone MAOA;MAOA DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;SOD1 1230:[DB09245 DB12478] DB09245|Toloxatone MAOA;MAOA DB12478|Piribedil DRD2;DRD3 common genes common pathways 1231:[DB09245 DB00824] DB09245|Toloxatone MAOA;MAOA DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways 1232:[DB09245 DB11834] DB09245|Toloxatone MAOA;MAOA DB11834|Guselkumab IL23A common genes common pathways 1233:[DB09245 DB08906] DB09245|Toloxatone MAOA;MAOA DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C8 1234:[DB09245 DB02546] DB09245|Toloxatone MAOA;MAOA DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways 1235:[DB09245 DB00848] DB09245|Toloxatone MAOA;MAOA DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways 1236:[DB09245 DB04947] DB09245|Toloxatone MAOA;MAOA DB04947|Altropane SLC6A3 common genes common pathways GO:0042420| dopamine catabolic process SLC6A3;MAOA 1237:[DB09245 DB01860] DB09245|Toloxatone MAOA;MAOA DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 1238:[DB09245 DB02226] DB09245|Toloxatone MAOA;MAOA DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 1239:[DB09245 DB09018] DB09245|Toloxatone MAOA;MAOA DB09018|Bromopride DRD2 common genes common pathways 1240:[DB09245 DB01096] DB09245|Toloxatone MAOA;MAOA DB01096|Oxamniquine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 1241:[DB09245 DB06587] DB09245|Toloxatone MAOA;MAOA DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1242:[DB09245 DB05990] DB09245|Toloxatone MAOA;MAOA DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1243:[DB09245 DB05797] DB09245|Toloxatone MAOA;MAOA DB05797|TNX-901 FCER1A common genes common pathways 1244:[DB09245 DB04700] DB09245|Toloxatone MAOA;MAOA DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;GSTK1 1245:[DB09245 DB04593] DB09245|Toloxatone MAOA;MAOA DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways 1246:[DB09245 DB02209] DB09245|Toloxatone MAOA;MAOA DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0055114| oxidation-reduction process PNPO;MAOA 1247:[DB09245 DB05088] DB09245|Toloxatone MAOA;MAOA DB05088|Tiomolibdate ion APP common genes common pathways 1248:[DB09245 DB08590] DB09245|Toloxatone MAOA;MAOA DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways 1249:[DB09245 DB05749] DB09245|Toloxatone MAOA;MAOA DB05749|MPI-674 CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;MAOA 1250:[DB09245 DB01256] DB09245|Toloxatone MAOA;MAOA DB01256|Retapamulin rplC;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1251:[DB09245 DB04345] DB09245|Toloxatone MAOA;MAOA DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways GO:0055114| oxidation-reduction process MAOA;BLVRB 1252:[DB09245 DB13192] DB09245|Toloxatone MAOA;MAOA DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways 1253:[DB09245 DB01564] DB09245|Toloxatone MAOA;MAOA DB01564|Calusterone AR common genes common pathways 1254:[DB09245 DB08895] DB09245|Toloxatone MAOA;MAOA DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;MAOA;CYP3A4 1255:[DB09245 DB05005] DB09245|Toloxatone MAOA;MAOA DB05005|CCX282 CCR9 common genes common pathways 1256:[DB09245 DB08008] DB09245|Toloxatone MAOA;MAOA DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1257:[DB09245 DB14539] DB09245|Toloxatone MAOA;MAOA DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP11B2;CYP11B1;HSD3B1;HSD11B2;CYP3A5;CYP2C8 1258:[DB09245 DB03686] DB09245|Toloxatone MAOA;MAOA DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways 1259:[DB09245 DB03309] DB09245|Toloxatone MAOA;MAOA DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways 1260:[DB09245 DB04003] DB09245|Toloxatone MAOA;MAOA DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways 1261:[DB09245 DB04767] DB09245|Toloxatone MAOA;MAOA DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways 1262:[DB09245 DB05885] DB09245|Toloxatone MAOA;MAOA DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1263:[DB09245 DB08588] DB09245|Toloxatone MAOA;MAOA DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways 1264:[DB09245 DB08504] DB09245|Toloxatone MAOA;MAOA DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways 1265:[DB09245 DB06013] DB09245|Toloxatone MAOA;MAOA DB06013|Aldoxorubicin TOP2A common genes common pathways 1266:[DB09245 DB05968] DB09245|Toloxatone MAOA;MAOA DB05968|PR-104 TNF common genes common pathways 1267:[DB09245 DB14004] DB09245|Toloxatone MAOA;MAOA DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP4A11 1268:[DB09245 DB03167] DB09245|Toloxatone MAOA;MAOA DB03167|Pentabromophenol TTR common genes common pathways 1269:[DB09245 DB05786] DB09245|Toloxatone MAOA;MAOA DB05786|Irofulven FUBP1 common genes common pathways 1270:[DB09245 DB00822] DB09245|Toloxatone MAOA;MAOA DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process DBH;CYP3A5;CYP3A4;CYP2E1;ALDH2;MAOA GO:0042420| dopamine catabolic process MAOA;DBH 1271:[DB09245 DB06907] DB09245|Toloxatone MAOA;MAOA DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways 1272:[DB09245 DB05014] DB09245|Toloxatone MAOA;MAOA DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways 1273:[DB09245 DB11590] DB09245|Toloxatone MAOA;MAOA DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;GPX1;SOD2;GSR 1274:[DB09245 DB06481] DB09245|Toloxatone MAOA;MAOA DB06481|Manitimus DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1275:[DB09245 DB09378] DB09245|Toloxatone MAOA;MAOA DB09378|Fluprednisolone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1276:[DB09245 DB12026] DB09245|Toloxatone MAOA;MAOA DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP3A4;CYP2C8 1277:[DB09245 DB00250] DB09245|Toloxatone MAOA;MAOA DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2C9;CYP3A4;FMO3;MAOA;CYP3A7;PTGS2;CYP3A5;CYP2C8;CYP2C19;CYP2C18;MPO;PTGS1 1278:[DB09245 DB07015] DB09245|Toloxatone MAOA;MAOA DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways 1279:[DB09245 DB00167] DB09245|Toloxatone MAOA;MAOA DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process ACADSB;MAOA 1280:[DB09245 DB02638] DB09245|Toloxatone MAOA;MAOA DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways 1281:[DB09245 DB05159] DB09245|Toloxatone MAOA;MAOA DB05159|CCX915 CCR2 common genes common pathways 1282:[DB09245 DB06069] DB09245|Toloxatone MAOA;MAOA DB06069|XMT-1001 TOP1 common genes common pathways 1283:[DB09245 DB02074] DB09245|Toloxatone MAOA;MAOA DB02074|Butenoic Acid FABP1 common genes common pathways 1284:[DB09245 DB14033] DB09245|Toloxatone MAOA;MAOA DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9 1285:[DB09245 DB05712] DB09245|Toloxatone MAOA;MAOA DB05712|AZD-9684 CPB2 common genes common pathways 1286:[DB09245 DB00467] DB09245|Toloxatone MAOA;MAOA DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1287:[DB09245 DB08837] DB09245|Toloxatone MAOA;MAOA DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways 1288:[DB09245 DB03336] DB09245|Toloxatone MAOA;MAOA DB03336|BIA COMT common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;COMT GO:0006584| catecholamine metabolic process MAOA;COMT GO:0042420| dopamine catabolic process COMT;MAOA 1289:[DB09245 DB06817] DB09245|Toloxatone MAOA;MAOA DB06817|Raltegravir pol;UGT1A1 common genes common pathways 1290:[DB09245 DB09124] DB09245|Toloxatone MAOA;MAOA DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1291:[DB09245 DB06892] DB09245|Toloxatone MAOA;MAOA DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways 1292:[DB09245 DB05553] DB09245|Toloxatone MAOA;MAOA DB05553|Regrelor P2RY12 common genes common pathways 1293:[DB09245 DB08672] DB09245|Toloxatone MAOA;MAOA DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways 1294:[DB09245 DB07176] DB09245|Toloxatone MAOA;MAOA DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways 1295:[DB09245 DB09383] DB09245|Toloxatone MAOA;MAOA DB09383|Meprednisone CYP3A4;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1296:[DB09245 DB14009] DB09245|Toloxatone MAOA;MAOA DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CAT;CYP3A5;CYP1B1;PTGS1;ALOX5;GPX1;SOD1;CRYZ;CYP3A4;CYP2C9;CYP1A1;HMGCR;CYP3A7;PTGS2;CYP1A2;MAOA 1297:[DB09245 DB00137] DB09245|Toloxatone MAOA;MAOA DB00137|Lutein ALB common genes common pathways 1298:[DB09245 DB01345] DB09245|Toloxatone MAOA;MAOA DB01345|Potassium cation ATP1A1 common genes common pathways 1299:[DB09245 DB00505] DB09245|Toloxatone MAOA;MAOA DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways 1300:[DB09245 DB00166] DB09245|Toloxatone MAOA;MAOA DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0055114| oxidation-reduction process POR;MAOA 1301:[DB09245 DB04149] DB09245|Toloxatone MAOA;MAOA DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways 1302:[DB09245 DB11635] DB09245|Toloxatone MAOA;MAOA DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0055114| oxidation-reduction process CYP4F2;CYP3A4;MAOA 1303:[DB09245 DB08370] DB09245|Toloxatone MAOA;MAOA DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways 1304:[DB09245 DB06785] DB09245|Toloxatone MAOA;MAOA DB06785|Ganirelix GNRHR common genes common pathways 1305:[DB09245 DB11235] DB09245|Toloxatone MAOA;MAOA DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 1306:[DB09245 DB13620] DB09245|Toloxatone MAOA;MAOA DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways 1307:[DB09245 DB05137] DB09245|Toloxatone MAOA;MAOA DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways 1308:[DB09245 DB14071] DB09245|Toloxatone MAOA;MAOA DB14071|Desmethylsertraline ABCB1 common genes common pathways 1309:[DB09245 DB07101] DB09245|Toloxatone MAOA;MAOA DB07101|PD-0325901 MAP2K1 common genes common pathways 1310:[DB09245 DB04754] DB09245|Toloxatone MAOA;MAOA DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways 1311:[DB09245 DB03695] DB09245|Toloxatone MAOA;MAOA DB03695|Piritrexim DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 1312:[DB09245 DB02877] DB09245|Toloxatone MAOA;MAOA DB02877|Arotinoid acid RARB common genes common pathways 1313:[DB09245 DB08454] DB09245|Toloxatone MAOA;MAOA DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways 1314:[DB09245 DB00238] DB09245|Toloxatone MAOA;MAOA DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2C9;CYP3A4;CYP2B6;CYP2A6;CYP3A5;CYP2D6 1315:[DB09245 DB11792] DB09245|Toloxatone MAOA;MAOA DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP3A5;MAOA;CYP3A7;CYP3A4 1316:[DB09245 DB03856] DB09245|Toloxatone MAOA;MAOA DB03856|L-Eflornithine ODC1 common genes common pathways 1317:[DB09245 DB07339] DB09245|Toloxatone MAOA;MAOA DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NQO2 1318:[DB09245 DB04956] DB09245|Toloxatone MAOA;MAOA DB04956|Afelimomab TNF common genes common pathways 1319:[DB09245 DB06471] DB09245|Toloxatone MAOA;MAOA DB06471|Naxifylline ADORA1 common genes common pathways 1320:[DB09245 DB01933] DB09245|Toloxatone MAOA;MAOA DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways 1321:[DB09245 DB03606] DB09245|Toloxatone MAOA;MAOA DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways 1322:[DB09245 DB03977] DB09245|Toloxatone MAOA;MAOA DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYCS 1323:[DB09245 DB11274] DB09245|Toloxatone MAOA;MAOA DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1324:[DB09245 DB00070] DB09245|Toloxatone MAOA;MAOA DB00070|Hyaluronidase TGFB1;ALB common genes common pathways 1325:[DB09245 DB06468] DB09245|Toloxatone MAOA;MAOA DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0055114| oxidation-reduction process MAOA;MPO 1326:[DB09245 DB07638] DB09245|Toloxatone MAOA;MAOA DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways 1327:[DB09245 DB06833] DB09245|Toloxatone MAOA;MAOA DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways 1328:[DB09245 DB13932] DB09245|Toloxatone MAOA;MAOA DB13932|Voretigene Neparvovec RPE65 common genes common pathways GO:0055114| oxidation-reduction process MAOA;RPE65 1329:[DB09245 DB06358] DB09245|Toloxatone MAOA;MAOA DB06358|Iclaprim DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 1330:[DB09245 DB02306] DB09245|Toloxatone MAOA;MAOA DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 1331:[DB09245 DB08089] DB09245|Toloxatone MAOA;MAOA DB08089|LGD-2226 AR common genes common pathways 1332:[DB09245 DB01044] DB09245|Toloxatone MAOA;MAOA DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 1333:[DB09245 DB04012] DB09245|Toloxatone MAOA;MAOA DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways 1334:[DB09245 DB02557] DB09245|Toloxatone MAOA;MAOA DB02557|Phosphoramidon MME;KEL common genes common pathways 1335:[DB09245 DB04281] DB09245|Toloxatone MAOA;MAOA DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1336:[DB09245 DB04894] DB09245|Toloxatone MAOA;MAOA DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1337:[DB09245 DB00772] DB09245|Toloxatone MAOA;MAOA DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;MAOA;CYP1A2 1338:[DB09245 DB07135] DB09245|Toloxatone MAOA;MAOA DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways 1339:[DB09245 DB01206] DB09245|Toloxatone MAOA;MAOA DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;MAOA 1340:[DB09245 DB09079] DB09245|Toloxatone MAOA;MAOA DB09079|Nintedanib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FLT3;LCK;LYN;SRC;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1341:[DB09245 DB12001] DB09245|Toloxatone MAOA;MAOA DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1342:[DB09245 DB07525] DB09245|Toloxatone MAOA;MAOA DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways 1343:[DB09245 DB06993] DB09245|Toloxatone MAOA;MAOA DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways 1344:[DB09245 DB02919] DB09245|Toloxatone MAOA;MAOA DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 1345:[DB09245 DB01131] DB09245|Toloxatone MAOA;MAOA DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;DHFR;CYP3A4;CYP2E1;CYP2C9;MAOA 1346:[DB09245 DB07141] DB09245|Toloxatone MAOA;MAOA DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 1347:[DB09245 DB05078] DB09245|Toloxatone MAOA;MAOA DB05078|AER001 IL4R;IL13RA2 common genes common pathways 1348:[DB09245 DB05332] DB09245|Toloxatone MAOA;MAOA DB05332|Romiplostim MPL common genes common pathways 1349:[DB09245 DB01045] DB09245|Toloxatone MAOA;MAOA DB01045|Rifampicin rpoB;rpoC;NR1I2;SLCO1B1;SLCO1A2;SLCO1B3;CYP51A1;ALB;SLCO2B1;CYP2C9;CYP1A2;CYP2C8;CYP3A4;CYP2B6;UGT1A1;CYP2C19;CYP2A6;CYP2E1;CYP3A43;CYP3A7;CYP4A11;CYP2D6;ABCB1;SLCO1B3;ABCC1;SLCO2B1;ABCB11;SLCO1A2;SLC22A7;SLCO1B1;ABCC5;ABCC2;ABCC3;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP2C19;CYP2C8;CYP2D6;CYP1A2;MAOA;CYP4A11;CYP51A1;CYP3A7;CYP2C9;CYP2E1;CYP3A4;CYP2B6;CYP2A6 1350:[DB09245 DB05339] DB09245|Toloxatone MAOA;MAOA DB05339|MN-305 HTR1A common genes common pathways 1351:[DB09245 DB07036] DB09245|Toloxatone MAOA;MAOA DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways 1352:[DB09245 DB00110] DB09245|Toloxatone MAOA;MAOA DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 1353:[DB09245 DB01094] DB09245|Toloxatone MAOA;MAOA DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1354:[DB09245 DB05139] DB09245|Toloxatone MAOA;MAOA DB05139|CR002 PDGFD common genes common pathways 1355:[DB09245 DB11275] DB09245|Toloxatone MAOA;MAOA DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways 1356:[DB09245 DB00650] DB09245|Toloxatone MAOA;MAOA DB00650|Leucovorin SLC22A8 common genes common pathways 1357:[DB09245 DB08980] DB09245|Toloxatone MAOA;MAOA DB08980|Fendiline CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1358:[DB09245 DB09183] DB09245|Toloxatone MAOA;MAOA DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;MAOA 1359:[DB09245 DB05001] DB09245|Toloxatone MAOA;MAOA DB05001|PSN9301 DPP4 common genes common pathways 1360:[DB09245 DB00111] DB09245|Toloxatone MAOA;MAOA DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 1361:[DB09245 DB13933] DB09245|Toloxatone MAOA;MAOA DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0055114| oxidation-reduction process MAOA;F8 1362:[DB09245 DB04796] DB09245|Toloxatone MAOA;MAOA DB04796|Inecalcitol VDR common genes common pathways 1363:[DB09245 DB08574] DB09245|Toloxatone MAOA;MAOA DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 1364:[DB09245 DB00568] DB09245|Toloxatone MAOA;MAOA DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP1A1;CYP2C9;CYP3A4;CYP2B6;CYP2A6;MAOA;CYP1A2 1365:[DB09245 DB07768] DB09245|Toloxatone MAOA;MAOA DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0055114| oxidation-reduction process AKR1C2;MAOA;AKR1C1 1366:[DB09245 DB05482] DB09245|Toloxatone MAOA;MAOA DB05482|7-ethyl-10-hydroxycamptothecin TOP1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1367:[DB09245 DB01053] DB09245|Toloxatone MAOA;MAOA DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways 1368:[DB09245 DB03247] DB09245|Toloxatone MAOA;MAOA DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0055114| oxidation-reduction process POR;DPYD;HAO2;PNPO;DHODH;HAO1;MAOA;NOS1;BLVRB 1369:[DB09245 DB03907] DB09245|Toloxatone MAOA;MAOA DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0006584| catecholamine metabolic process COMT;MAOA GO:0042420| dopamine catabolic process MAOA;COMT GO:0042135| neurotransmitter catabolic process COMT;MAOA 1370:[DB09245 DB01085] DB09245|Toloxatone MAOA;MAOA DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2A6;CYP2E1;CYP3A4 1371:[DB09245 DB06354] DB09245|Toloxatone MAOA;MAOA DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways 1372:[DB09245 DB12773] DB09245|Toloxatone MAOA;MAOA DB12773|Sifalimumab IFNA2 common genes common pathways 1373:[DB09245 DB00227] DB09245|Toloxatone MAOA;MAOA DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP3A7;MAOA;CYP3A4;CYP2C9;CYP2D6;CYP2C8;CYP3A5 1374:[DB09245 DB04521] DB09245|Toloxatone MAOA;MAOA DB04521|GSHNA GSTA3 common genes common pathways 1375:[DB09245 DB04756] DB09245|Toloxatone MAOA;MAOA DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways 1376:[DB09245 DB01645] DB09245|Toloxatone MAOA;MAOA DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;MAOA;CYP1A2;CYP2C8;CYP1B1 1377:[DB09245 DB11731] DB09245|Toloxatone MAOA;MAOA DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways 1378:[DB09245 DB04753] DB09245|Toloxatone MAOA;MAOA DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways 1379:[DB09245 DB01033] DB09245|Toloxatone MAOA;MAOA DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;XDH;MAOA;AOX1;IMPDH2;IMPDH1 1380:[DB09245 DB05883] DB09245|Toloxatone MAOA;MAOA DB05883|ABX-PTH PTH common genes common pathways 1381:[DB09245 DB06372] DB09245|Toloxatone MAOA;MAOA DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways 1382:[DB09245 DB00365] DB09245|Toloxatone MAOA;MAOA DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;MAOA 1383:[DB09245 DB07443] DB09245|Toloxatone MAOA;MAOA DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1384:[DB09245 DB11619] DB09245|Toloxatone MAOA;MAOA DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1385:[DB09245 DB07032] DB09245|Toloxatone MAOA;MAOA DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways 1386:[DB09245 DB00024] DB09245|Toloxatone MAOA;MAOA DB00024|Thyrotropin alfa TSHR common genes common pathways 1387:[DB09245 DB05814] DB09245|Toloxatone MAOA;MAOA DB05814|GPI-1485 FKBP1A;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1388:[DB09245 DB08844] DB09245|Toloxatone MAOA;MAOA DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways 1389:[DB09245 DB09110] DB09245|Toloxatone MAOA;MAOA DB09110|Coenzyme M GSR common genes common pathways GO:0055114| oxidation-reduction process MAOA;GSR 1390:[DB09245 DB00810] DB09245|Toloxatone MAOA;MAOA DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 1391:[DB09245 DB09460] DB09245|Toloxatone MAOA;MAOA DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways 1392:[DB09245 DB01405] DB09245|Toloxatone MAOA;MAOA DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1393:[DB09245 DB02613] DB09245|Toloxatone MAOA;MAOA DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 1394:[DB09245 DB05361] DB09245|Toloxatone MAOA;MAOA DB05361|SR-123781A SERPINC1;F2R common genes common pathways 1395:[DB09245 DB08875] DB09245|Toloxatone MAOA;MAOA DB08875|Cabozantinib MET;KDR;RET;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;MAOA;CYP2C8 1396:[DB09245 DB08784] DB09245|Toloxatone MAOA;MAOA DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 1397:[DB09245 DB02285] DB09245|Toloxatone MAOA;MAOA DB02285|Protoporphyrin FTL common genes common pathways 1398:[DB09245 DB00038] DB09245|Toloxatone MAOA;MAOA DB00038|Oprelvekin IL11RA common genes common pathways 1399:[DB09245 DB06231] DB09245|Toloxatone MAOA;MAOA DB06231|Caldaret SLC8A1 common genes common pathways 1400:[DB09245 DB13941] DB09245|Toloxatone MAOA;MAOA DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP2B6;MAOA 1401:[DB09245 DB00160] DB09245|Toloxatone MAOA;MAOA DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ABAT 1402:[DB09245 DB00764] DB09245|Toloxatone MAOA;MAOA DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA 1403:[DB09245 DB00596] DB09245|Toloxatone MAOA;MAOA DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways 1404:[DB09245 DB07008] DB09245|Toloxatone MAOA;MAOA DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 1405:[DB09245 DB00694] DB09245|Toloxatone MAOA;MAOA DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;MAOA;XDH;CYP3A5;POR;CYP1B1 1406:[DB09245 DB00094] DB09245|Toloxatone MAOA;MAOA DB00094|Urofollitropin FSHR common genes common pathways 1407:[DB09245 DB11639] DB09245|Toloxatone MAOA;MAOA DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways 1408:[DB09245 DB11075] DB09245|Toloxatone MAOA;MAOA DB11075|Hypromellose EPCAM common genes common pathways 1409:[DB09245 DB00385] DB09245|Toloxatone MAOA;MAOA DB00385|Valrubicin TOP2A common genes common pathways 1410:[DB09245 DB14596] DB09245|Toloxatone MAOA;MAOA DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1411:[DB09245 DB00920] DB09245|Toloxatone MAOA;MAOA DB00920|Ketotifen HRH1;PGD common genes common pathways GO:0055114| oxidation-reduction process MAOA;PGD 1412:[DB09245 DB08874] DB09245|Toloxatone MAOA;MAOA DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1413:[DB09245 DB00033] DB09245|Toloxatone MAOA;MAOA DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 1414:[DB09245 DB00857] DB09245|Toloxatone MAOA;MAOA DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP11A1;CYP2C9;CYP19A1;CYP3A4;MAOA;CYP1A2;CYP2C19;CYP2C8;CYP2D6;SQLE;PTGS1 1415:[DB09245 DB08168] DB09245|Toloxatone MAOA;MAOA DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways 1416:[DB09245 DB13997] DB09245|Toloxatone MAOA;MAOA DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1417:[DB09245 DB01083] DB09245|Toloxatone MAOA;MAOA DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways GO:0055114| oxidation-reduction process LIPF;FASN;CYP3A4;MAOA 1418:[DB09245 DB08044] DB09245|Toloxatone MAOA;MAOA DB08044|ABT-341 DPP4 common genes common pathways 1419:[DB09245 DB14582] DB09245|Toloxatone MAOA;MAOA DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways 1420:[DB09245 DB05442] DB09245|Toloxatone MAOA;MAOA DB05442|Etiprednol dicloacetate IL1B common genes common pathways 1421:[DB09245 DB09060] DB09245|Toloxatone MAOA;MAOA DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways 1422:[DB09245 DB04733] DB09245|Toloxatone MAOA;MAOA DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways 1423:[DB09245 DB04114] DB09245|Toloxatone MAOA;MAOA DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 1424:[DB09245 DB08912] DB09245|Toloxatone MAOA;MAOA DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9;CYP3A4;CYP2B6;CYP2C8 1425:[DB09245 DB01599] DB09245|Toloxatone MAOA;MAOA DB01599|Probucol ABCA1;CES1 common genes common pathways 1426:[DB09245 DB02485] DB09245|Toloxatone MAOA;MAOA DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 1427:[DB09245 DB09046] DB09245|Toloxatone MAOA;MAOA DB09046|Metreleptin LEPR common genes common pathways 1428:[DB09245 DB05936] DB09245|Toloxatone MAOA;MAOA DB05936|CVT-6883 ADORA2B common genes common pathways 1429:[DB09245 DB03604] DB09245|Toloxatone MAOA;MAOA DB03604|Tiratricol THRB common genes common pathways 1430:[DB09245 DB00378] DB09245|Toloxatone MAOA;MAOA DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1431:[DB09245 DB01005] DB09245|Toloxatone MAOA;MAOA DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;RRM1;CYP2D6 1432:[DB09245 DB01425] DB09245|Toloxatone MAOA;MAOA DB01425|Alizapride DRD2 common genes common pathways 1433:[DB09245 DB01057] DB09245|Toloxatone MAOA;MAOA DB01057|Echothiophate BCHE;ALB common genes common pathways 1434:[DB09245 DB01998] DB09245|Toloxatone MAOA;MAOA DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways 1435:[DB09245 DB13168] DB09245|Toloxatone MAOA;MAOA DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOA;FADS1;FADS2;ALOX5 1436:[DB09245 DB03066] DB09245|Toloxatone MAOA;MAOA DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 1437:[DB09245 DB11892] DB09245|Toloxatone MAOA;MAOA DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1438:[DB09245 DB06756] DB09245|Toloxatone MAOA;MAOA DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0055114| oxidation-reduction process PRODH;MAOA 1439:[DB09245 DB07389] DB09245|Toloxatone MAOA;MAOA DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 1440:[DB09245 DB09332] DB09245|Toloxatone MAOA;MAOA DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0055114| oxidation-reduction process POR;MAOA;VKORC1 1441:[DB09245 DB08051] DB09245|Toloxatone MAOA;MAOA DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways 1442:[DB09245 DB03023] DB09245|Toloxatone MAOA;MAOA DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways 1443:[DB09245 DB11779] DB09245|Toloxatone MAOA;MAOA DB11779|Danoprevir CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1444:[DB09245 DB00550] DB09245|Toloxatone MAOA;MAOA DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0042420| dopamine catabolic process DBH;MAOA GO:0055114| oxidation-reduction process MAOA;TPO;CYP1A1;MPO;DBH 1445:[DB09245 DB06419] DB09245|Toloxatone MAOA;MAOA DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP3A4 1446:[DB09245 DB11960] DB09245|Toloxatone MAOA;MAOA DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1447:[DB09245 DB05130] DB09245|Toloxatone MAOA;MAOA DB05130|INCB3284 CCR2 common genes common pathways 1448:[DB09245 DB09052] DB09245|Toloxatone MAOA;MAOA DB09052|Blinatumomab CD19;CD3D common genes common pathways 1449:[DB09245 DB08834] DB09245|Toloxatone MAOA;MAOA DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways 1450:[DB09245 DB06589] DB09245|Toloxatone MAOA;MAOA DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP1A2;MAOA;CYP3A4 1451:[DB09245 DB03153] DB09245|Toloxatone MAOA;MAOA DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 1452:[DB09245 DB12651] DB09245|Toloxatone MAOA;MAOA DB12651|Bardoxolone CASP8 common genes common pathways 1453:[DB09245 DB12489] DB09245|Toloxatone MAOA;MAOA DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1454:[DB09245 DB00145] DB09245|Toloxatone MAOA;MAOA DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process PIPOX;GLDC;MAOA 1455:[DB09245 DB04410] DB09245|Toloxatone MAOA;MAOA DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways 1456:[DB09245 DB11805] DB09245|Toloxatone MAOA;MAOA DB11805|Saracatinib CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1457:[DB09245 DB01708] DB09245|Toloxatone MAOA;MAOA DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process HSD17B1;CYP3A4;MAOA;CYP3A7 1458:[DB09245 DB14017] DB09245|Toloxatone MAOA;MAOA DB14017|H3B-8800 SF3B1 common genes common pathways 1459:[DB09245 DB01108] DB09245|Toloxatone MAOA;MAOA DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;HSD3B2;HSD3B1 1460:[DB09245 DB00052] DB09245|Toloxatone MAOA;MAOA DB00052|Somatotropin GHR;PRLR common genes common pathways 1461:[DB09245 DB05967] DB09245|Toloxatone MAOA;MAOA DB05967|ANZ-100 KISS1R common genes common pathways 1462:[DB09245 DB12243] DB09245|Toloxatone MAOA;MAOA DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways 1463:[DB09245 DB05448] DB09245|Toloxatone MAOA;MAOA DB05448|PX-12 TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;TXNRD1 1464:[DB09245 DB11830] DB09245|Toloxatone MAOA;MAOA DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways 1465:[DB09245 DB05532] DB09245|Toloxatone MAOA;MAOA DB05532|BMS-488043 FFAR4 common genes common pathways 1466:[DB09245 DB05449] DB09245|Toloxatone MAOA;MAOA DB05449|FM-VP4 ABCB1 common genes common pathways 1467:[DB09245 DB07180] DB09245|Toloxatone MAOA;MAOA DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways 1468:[DB09245 DB09348] DB09245|Toloxatone MAOA;MAOA DB09348|Propiolactone ALB common genes common pathways 1469:[DB09245 DB04988] DB09245|Toloxatone MAOA;MAOA DB04988|IGN311 EGFR;ERBB2 common genes common pathways 1470:[DB09245 DB08058] DB09245|Toloxatone MAOA;MAOA DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 1471:[DB09245 DB09539] DB09245|Toloxatone MAOA;MAOA DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways 1472:[DB09245 DB03953] DB09245|Toloxatone MAOA;MAOA DB03953|L-Thiocitrulline NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 1473:[DB09245 DB06733] DB09245|Toloxatone MAOA;MAOA DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 1474:[DB09245 DB02933] DB09245|Toloxatone MAOA;MAOA DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 1475:[DB09245 DB02056] DB09245|Toloxatone MAOA;MAOA DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;AKR1C3 1476:[DB09245 DB01294] DB09245|Toloxatone MAOA;MAOA DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 1477:[DB09245 DB06643] DB09245|Toloxatone MAOA;MAOA DB06643|Denosumab TNFSF11 common genes common pathways 1478:[DB09245 DB00105] DB09245|Toloxatone MAOA;MAOA DB00105|Interferon Alfa-2b, Recombinant IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 1479:[DB09245 DB03166] DB09245|Toloxatone MAOA;MAOA DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways 1480:[DB09245 DB07616] DB09245|Toloxatone MAOA;MAOA DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways 1481:[DB09245 DB04576] DB09245|Toloxatone MAOA;MAOA DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1482:[DB09245 DB02337] DB09245|Toloxatone MAOA;MAOA DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 1483:[DB09245 DB14641] DB09245|Toloxatone MAOA;MAOA DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways 1484:[DB09245 DB00116] DB09245|Toloxatone MAOA;MAOA DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process ALDH1L1;MAOA;MTHFD1;MTHFD2;MTHFR 1485:[DB09245 DB02158] DB09245|Toloxatone MAOA;MAOA DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 1486:[DB09245 DB00767] DB09245|Toloxatone MAOA;MAOA DB00767|Benzquinamide HRH1;CHRM4;CHRM1;CHRM5;CHRM2;CHRM3 common genes common pathways 1487:[DB09245 DB05033] DB09245|Toloxatone MAOA;MAOA DB05033|INCB7839 ADAM9 common genes common pathways 1488:[DB09245 DB13998] DB09245|Toloxatone MAOA;MAOA DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0055114| oxidation-reduction process MAOA;PHYH 1489:[DB09245 DB08835] DB09245|Toloxatone MAOA;MAOA DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways 1490:[DB09245 DB05460] DB09245|Toloxatone MAOA;MAOA DB05460|Ezatiostat GSTP1 common genes common pathways 1491:[DB09245 DB03288] DB09245|Toloxatone MAOA;MAOA DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways 1492:[DB09245 DB05299] DB09245|Toloxatone MAOA;MAOA DB05299|keyhole limpet hemocyanin IL2 common genes common pathways 1493:[DB09245 DB04877] DB09245|Toloxatone MAOA;MAOA DB04877|Voacamine ABCB1 common genes common pathways 1494:[DB09245 DB02105] DB09245|Toloxatone MAOA;MAOA DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0042135| neurotransmitter catabolic process COMT;MAOA GO:0042420| dopamine catabolic process MAOA;COMT GO:0006584| catecholamine metabolic process MAOA;COMT 1495:[DB09245 DB04960] DB09245|Toloxatone MAOA;MAOA DB04960|Tipifarnib FNTB common genes common pathways 1496:[DB09245 DB03203] DB09245|Toloxatone MAOA;MAOA DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways 1497:[DB09245 DB13988] DB09245|Toloxatone MAOA;MAOA DB13988|SB-269970 HTR7 common genes common pathways 1498:[DB09245 DB11726] DB09245|Toloxatone MAOA;MAOA DB11726|Encenicline CHRNA7 common genes common pathways 1499:[DB09245 DB00745] DB09245|Toloxatone MAOA;MAOA DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0042420| dopamine catabolic process SLC6A3;MAOA GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2B6;CYP1A2;MAOA;CYP3A5;CYP2C19 1500:[DB09245 DB04657] DB09245|Toloxatone MAOA;MAOA DB04657|Carboxin SDHA common genes common pathways GO:0055114| oxidation-reduction process SDHA;MAOA 1501:[DB09245 DB01234] DB09245|Toloxatone MAOA;MAOA DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;CYP4A11;CYP3A4;CYP19A1;CYP1A1;CYP2E1;NOS2;CYP2A6;CYP11A1;CYP2B6;CYP1B1;CYP3A43;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP2C8 1502:[DB09245 DB00779] DB09245|Toloxatone MAOA;MAOA DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process TDO2;MAOA 1503:[DB09245 DB05928] DB09245|Toloxatone MAOA;MAOA DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP1A1;CYP3A4;MAOA;CYP1A2 1504:[DB09245 DB01086] DB09245|Toloxatone MAOA;MAOA DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes common pathways 1505:[DB09245 DB00858] DB09245|Toloxatone MAOA;MAOA DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;MAOA 1506:[DB09245 DB01562] DB09245|Toloxatone MAOA;MAOA DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 1507:[DB09245 DB02853] DB09245|Toloxatone MAOA;MAOA DB02853|D-Proline SLC36A1 common genes common pathways 1508:[DB09245 DB04275] DB09245|Toloxatone MAOA;MAOA DB04275|N-acetylserotonin SPR common genes common pathways GO:0055114| oxidation-reduction process SPR;MAOA 1509:[DB09245 DB00016] DB09245|Toloxatone MAOA;MAOA DB00016|Erythropoietin EPOR common genes common pathways 1510:[DB09245 DB06704] DB09245|Toloxatone MAOA;MAOA DB06704|Iobenguane SLC6A2 common genes common pathways 1511:[DB09245 DB07757] DB09245|Toloxatone MAOA;MAOA DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways 1512:[DB09245 DB08553] DB09245|Toloxatone MAOA;MAOA DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways 1513:[DB09245 DB07544] DB09245|Toloxatone MAOA;MAOA DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways 1514:[DB09245 DB00142] DB09245|Toloxatone MAOA;MAOA DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0055114| oxidation-reduction process GLUD2;ALDH18A1;GLUD1;MAOA;AASS GO:0042135| neurotransmitter catabolic process MAOA;ABAT 1515:[DB09245 DB07444] DB09245|Toloxatone MAOA;MAOA DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways 1516:[DB09245 DB00439] DB09245|Toloxatone MAOA;MAOA DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A7;HMGCR;CYP2C9;CYP3A4;CYP2B6;CYP3A5;CYP2C8;CYP2D6 1517:[DB09245 DB13173] DB09245|Toloxatone MAOA;MAOA DB13173|Cerliponase alfa IGF2R common genes common pathways 1518:[DB09245 DB06680] DB09245|Toloxatone MAOA;MAOA DB06680|Asoprisnil PGR common genes common pathways 1519:[DB09245 DB05120] DB09245|Toloxatone MAOA;MAOA DB05120|AT1391 INSR common genes common pathways 1520:[DB09245 DB09207] DB09245|Toloxatone MAOA;MAOA DB09207|AS-8112 DRD2;DRD3 common genes common pathways 1521:[DB09245 DB04094] DB09245|Toloxatone MAOA;MAOA DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways 1522:[DB09245 DB08871] DB09245|Toloxatone MAOA;MAOA DB08871|Eribulin BCL2;TUBB1 common genes common pathways 1523:[DB09245 DB05996] DB09245|Toloxatone MAOA;MAOA DB05996|Glembatumumab vedotin GPNMB common genes common pathways 1524:[DB09245 DB05915] DB09245|Toloxatone MAOA;MAOA DB05915|MYO-029 MSTN common genes common pathways 1525:[DB09245 DB00304] DB09245|Toloxatone MAOA;MAOA DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1526:[DB09245 DB07981] DB09245|Toloxatone MAOA;MAOA DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1 1527:[DB09245 DB03048] DB09245|Toloxatone MAOA;MAOA DB03048|6-Carboxymethyluracil DPYD common genes common pathways GO:0055114| oxidation-reduction process MAOA;DPYD 1528:[DB09245 DB01106] DB09245|Toloxatone MAOA;MAOA DB01106|Levocabastine HRH1;NTSR2 common genes common pathways 1529:[DB09245 DB01210] DB09245|Toloxatone MAOA;MAOA DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 1530:[DB09245 DB02556] DB09245|Toloxatone MAOA;MAOA DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways 1531:[DB09245 DB06217] DB09245|Toloxatone MAOA;MAOA DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 1532:[DB09245 DB02570] DB09245|Toloxatone MAOA;MAOA DB02570|PD150606 CAPNS1 common genes common pathways 1533:[DB09245 DB07960] DB09245|Toloxatone MAOA;MAOA DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways 1534:[DB09245 DB02266] DB09245|Toloxatone MAOA;MAOA DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;AKR1C3;PTGS1 1535:[DB09245 DB02377] DB09245|Toloxatone MAOA;MAOA DB02377|Guanine PNP;gpt;GCH1 common genes common pathways 1536:[DB09245 DB12305] DB09245|Toloxatone MAOA;MAOA DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0042420| dopamine catabolic process MAOA;SLC6A3 1537:[DB09245 DB01619] DB09245|Toloxatone MAOA;MAOA DB01619|Phenindamine HRH1 common genes common pathways 1538:[DB09245 DB05892] DB09245|Toloxatone MAOA;MAOA DB05892|RI 624 NGF common genes common pathways 1539:[DB09245 DB07425] DB09245|Toloxatone MAOA;MAOA DB07425|Sobetirome THRB common genes common pathways 1540:[DB09245 DB02942] DB09245|Toloxatone MAOA;MAOA DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 1541:[DB09245 DB00973] DB09245|Toloxatone MAOA;MAOA DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4 1542:[DB09245 DB04153] DB09245|Toloxatone MAOA;MAOA DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0055114| oxidation-reduction process ADH5;MAOA 1543:[DB09245 DB09330] DB09245|Toloxatone MAOA;MAOA DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP3A4 1544:[DB09245 DB00051] DB09245|Toloxatone MAOA;MAOA DB00051|Adalimumab TNF common genes common pathways 1545:[DB09245 DB05740] DB09245|Toloxatone MAOA;MAOA DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways 1546:[DB09245 DB06670] DB09245|Toloxatone MAOA;MAOA DB06670|Odanacatib CTSK;CYP3A4;CYP2C8;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4 1547:[DB09245 DB00451] DB09245|Toloxatone MAOA;MAOA DB00451|Levothyroxine THRA;THRB;CYP2C8;UGT1A1;TTR;SERPINA7;ALB;SLCO1C1;SLC16A2;ABCB1;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4A1;SLCO4C1;SLC7A5;SLCO2B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA 1548:[DB09245 DB03756] DB09245|Toloxatone MAOA;MAOA DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA 1549:[DB09245 DB06362] DB09245|Toloxatone MAOA;MAOA DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 1550:[DB09245 DB04768] DB09245|Toloxatone MAOA;MAOA DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 1551:[DB09245 DB03052] DB09245|Toloxatone MAOA;MAOA DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process TBXAS1;MAOA 1552:[DB09245 DB06616] DB09245|Toloxatone MAOA;MAOA DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA 1553:[DB09245 DB00473] DB09245|Toloxatone MAOA;MAOA DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 1554:[DB09245 DB02467] DB09245|Toloxatone MAOA;MAOA DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways 1555:[DB09245 DB08103] DB09245|Toloxatone MAOA;MAOA DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways 1556:[DB09245 DB03147] DB09245|Toloxatone MAOA;MAOA DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes MAOA common pathways GO:0055114| oxidation-reduction process DPYD;POR;CYB5R1;GCDH;ACAD8;TXNRD1;DLD;AIFM1;DAO;GFER;ACADS;GSR;NDUFA9;ERO1B;ACADM;MAOA;MAOB;NQO2;XDH;IL4I1;FDXR;IVD;ACOX1;NOS1;NQO1;CYB5R3 GO:0006576| cellular biogenic amine metabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOB;MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0006584| catecholamine metabolic process MAOA GO:0042420| dopamine catabolic process MAOB;MAOA 1557:[DB09245 DB03485] DB09245|Toloxatone MAOA;MAOA DB03485|Alpha-D-Fucose LTF common genes common pathways 1558:[DB09245 DB14562] DB09245|Toloxatone MAOA;MAOA DB14562|Andexanet alfa TFPI common genes common pathways 1559:[DB09245 DB05252] DB09245|Toloxatone MAOA;MAOA DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 1560:[DB09245 DB03701] DB09245|Toloxatone MAOA;MAOA DB03701|Vanoxerine SLC6A3;CYP3A4 common genes common pathways GO:0042420| dopamine catabolic process MAOA;SLC6A3 GO:0055114| oxidation-reduction process MAOA;CYP3A4 1561:[DB09245 DB05015] DB09245|Toloxatone MAOA;MAOA DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2C9;CYP2C8 1562:[DB09245 DB07168] DB09245|Toloxatone MAOA;MAOA DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways 1563:[DB09245 DB01396] DB09245|Toloxatone MAOA;MAOA DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP11A1 1564:[DB09245 DB08995] DB09245|Toloxatone MAOA;MAOA DB08995|Diosmin AHR common genes common pathways 1565:[DB09245 DB01390] DB09245|Toloxatone MAOA;MAOA DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways 1566:[DB09245 DB06717] DB09245|Toloxatone MAOA;MAOA DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;MAOA 1567:[DB09245 DB02545] DB09245|Toloxatone MAOA;MAOA DB02545|Fexaramine NR1H4 common genes common pathways 1568:[DB09245 DB03619] DB09245|Toloxatone MAOA;MAOA DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways 1569:[DB09245 DB06374] DB09245|Toloxatone MAOA;MAOA DB06374|Elacestrant ESR1 common genes common pathways 1570:[DB09245 DB01723] DB09245|Toloxatone MAOA;MAOA DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways 1571:[DB09245 DB01439] DB09245|Toloxatone MAOA;MAOA DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 1572:[DB09245 DB00072] DB09245|Toloxatone MAOA;MAOA DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1 1573:[DB09245 DB07497] DB09245|Toloxatone MAOA;MAOA DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways 1574:[DB09245 DB00959] DB09245|Toloxatone MAOA;MAOA DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1575:[DB09245 DB01411] DB09245|Toloxatone MAOA;MAOA DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C9 1576:[DB09245 DB13146] DB09245|Toloxatone MAOA;MAOA DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;ABCC4 1577:[DB09245 DB09555] DB09245|Toloxatone MAOA;MAOA DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;MAOA 1578:[DB09245 DB05790] DB09245|Toloxatone MAOA;MAOA DB05790|SR 140333 TACR1 common genes common pathways 1579:[DB09245 DB01429] DB09245|Toloxatone MAOA;MAOA DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 1580:[DB09245 DB00379] DB09245|Toloxatone MAOA;MAOA DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2B6;MAOA;CYP1A2;CYP2D6 1581:[DB09245 DB07315] DB09245|Toloxatone MAOA;MAOA DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways 1582:[DB09245 DB00526] DB09245|Toloxatone MAOA;MAOA DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NQO1;CYP1A1;SOD1;MAOA;CYP1B1;MPO GO:0006584| catecholamine metabolic process MAOA;ATP7A 1583:[DB09245 DB04636] DB09245|Toloxatone MAOA;MAOA DB04636|Glutamine t-butyl ester QPCT common genes common pathways 1584:[DB09245 DB04676] DB09245|Toloxatone MAOA;MAOA DB04676|Dansyllysine IGHA2 common genes common pathways 1585:[DB09245 DB03276] DB09245|Toloxatone MAOA;MAOA DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways 1586:[DB09245 DB01127] DB09245|Toloxatone MAOA;MAOA DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP19A1;MAOA 1587:[DB09245 DB12952] DB09245|Toloxatone MAOA;MAOA DB12952|Methylprednisone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1588:[DB09245 DB02552] DB09245|Toloxatone MAOA;MAOA DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways 1589:[DB09245 DB08699] DB09245|Toloxatone MAOA;MAOA DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways 1590:[DB09245 DB07916] DB09245|Toloxatone MAOA;MAOA DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways 1591:[DB09245 DB03800] DB09245|Toloxatone MAOA;MAOA DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways 1592:[DB09245 DB03956] DB09245|Toloxatone MAOA;MAOA DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways 1593:[DB09245 DB02673] DB09245|Toloxatone MAOA;MAOA DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 1594:[DB09245 DB07356] DB09245|Toloxatone MAOA;MAOA DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways 1595:[DB09245 DB05052] DB09245|Toloxatone MAOA;MAOA DB05052|MF101 ESR2 common genes common pathways 1596:[DB09245 DB06243] DB09245|Toloxatone MAOA;MAOA DB06243|Eflornithine ODC1 common genes common pathways 1597:[DB09245 DB04789] DB09245|Toloxatone MAOA;MAOA DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways 1598:[DB09245 DB06448] DB09245|Toloxatone MAOA;MAOA DB06448|Lonafarnib FNTA;IGFBP3 common genes common pathways 1599:[DB09245 DB04540] DB09245|Toloxatone MAOA;MAOA DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes common pathways 1600:[DB09245 DB14540] DB09245|Toloxatone MAOA;MAOA DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP11B2;CYP11B1;HSD3B1;HSD11B2;CYP3A5;CYP2C8 1601:[DB09245 DB01369] DB09245|Toloxatone MAOA;MAOA DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1602:[DB09245 DB13953] DB09245|Toloxatone MAOA;MAOA DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP1A1;CYP3A7;MAOA;CYP1A2;HSD17B2;CYP3A5;CYP2C8;CYP2C19;CYP1B1 1603:[DB09245 DB09291] DB09245|Toloxatone MAOA;MAOA DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;MAOA 1604:[DB09245 DB07421] DB09245|Toloxatone MAOA;MAOA DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways 1605:[DB09245 DB01380] DB09245|Toloxatone MAOA;MAOA DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1606:[DB09245 DB14503] DB09245|Toloxatone MAOA;MAOA DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways 1607:[DB09245 DB02029] DB09245|Toloxatone MAOA;MAOA DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways 1608:[DB09245 DB03896] DB09245|Toloxatone MAOA;MAOA DB03896|Triphosphoric acid PAPOLA common genes common pathways 1609:[DB09245 DB06787] DB09245|Toloxatone MAOA;MAOA DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 1610:[DB09245 DB03860] DB09245|Toloxatone MAOA;MAOA DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways 1611:[DB09245 DB06652] DB09245|Toloxatone MAOA;MAOA DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;MAOA;CYP3A5 1612:[DB09245 DB06412] DB09245|Toloxatone MAOA;MAOA DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes MAOA common pathways GO:0006576| cellular biogenic amine metabolic process MAOA GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;SRD5A1;CYP3A5;CYP2D6;CYP3A43 GO:0006584| catecholamine metabolic process MAOA GO:0042420| dopamine catabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA 1613:[DB09245 DB01228] DB09245|Toloxatone MAOA;MAOA DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 1614:[DB09245 DB02559] DB09245|Toloxatone MAOA;MAOA DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 1615:[DB09245 DB02222] DB09245|Toloxatone MAOA;MAOA DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways 1616:[DB09245 DB07111] DB09245|Toloxatone MAOA;MAOA DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways 1617:[DB09245 DB08901] DB09245|Toloxatone MAOA;MAOA DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A5;MAOA;CYP3A4 1618:[DB09245 DB11581] DB09245|Toloxatone MAOA;MAOA DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1619:[DB09245 DB06241] DB09245|Toloxatone MAOA;MAOA DB06241|Clenoliximab CD4 common genes common pathways 1620:[DB09245 DB06713] DB09245|Toloxatone MAOA;MAOA DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1621:[DB09245 DB02126] DB09245|Toloxatone MAOA;MAOA DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways 1622:[DB09245 DB00637] DB09245|Toloxatone MAOA;MAOA DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;CYP3A4;CYP2J2;CYP3A5;CYP2D6 1623:[DB09245 DB08214] DB09245|Toloxatone MAOA;MAOA DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 1624:[DB09245 DB01254] DB09245|Toloxatone MAOA;MAOA DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process FMO3;CYP3A4;CYP1A1;CYP1A2;MAOA;CYP3A5;CYP1B1 1625:[DB09245 DB01059] DB09245|Toloxatone MAOA;MAOA DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP1A1;CYP3A7;MAOA;CYP1A2 1626:[DB09245 DB02779] DB09245|Toloxatone MAOA;MAOA DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways 1627:[DB09245 DB05303] DB09245|Toloxatone MAOA;MAOA DB05303|OMS-103HP TNF;IL1R1 common genes common pathways 1628:[DB09245 DB07171] DB09245|Toloxatone MAOA;MAOA DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways 1629:[DB09245 DB00002] DB09245|Toloxatone MAOA;MAOA DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 1630:[DB09245 DB02701] DB09245|Toloxatone MAOA;MAOA DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;LDHA;CYP3A4;CYP2E1;CYP2D6 1631:[DB09245 DB09146] DB09245|Toloxatone MAOA;MAOA DB09146|Iron saccharate HBA1;TF common genes common pathways 1632:[DB09245 DB09449] DB09245|Toloxatone MAOA;MAOA DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways 1633:[DB09245 DB02201] DB09245|Toloxatone MAOA;MAOA DB02201|Malonate Ion aroH;SDF2 common genes common pathways 1634:[DB09245 DB07146] DB09245|Toloxatone MAOA;MAOA DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways 1635:[DB09245 DB06772] DB09245|Toloxatone MAOA;MAOA DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8;CYP3A5 1636:[DB09245 DB07975] DB09245|Toloxatone MAOA;MAOA DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1637:[DB09245 DB08213] DB09245|Toloxatone MAOA;MAOA DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways 1638:[DB09245 DB06370] DB09245|Toloxatone MAOA;MAOA DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1;CYP2C9;CYP3A4;CYP2D6 1639:[DB09245 DB13866] DB09245|Toloxatone MAOA;MAOA DB13866|Etynodiol CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1640:[DB09245 DB02624] DB09245|Toloxatone MAOA;MAOA DB02624|Homoserine Lactone SLC9A1 common genes common pathways 1641:[DB09245 DB11348] DB09245|Toloxatone MAOA;MAOA DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways 1642:[DB09245 DB09389] DB09245|Toloxatone MAOA;MAOA DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1;CYP3A4;SRD5A1 1643:[DB09245 DB12191] DB09245|Toloxatone MAOA;MAOA DB12191|Obatoclax BCL2 common genes common pathways 1644:[DB09245 DB04352] DB09245|Toloxatone MAOA;MAOA DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 1645:[DB09245 DB03727] DB09245|Toloxatone MAOA;MAOA DB03727|Coproporphyrin I UROD common genes common pathways 1646:[DB09245 DB08406] DB09245|Toloxatone MAOA;MAOA DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 1647:[DB09245 DB06734] DB09245|Toloxatone MAOA;MAOA DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 1648:[DB09245 DB00578] DB09245|Toloxatone MAOA;MAOA DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways 1649:[DB09245 DB08461] DB09245|Toloxatone MAOA;MAOA DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways 1650:[DB09245 DB08751] DB09245|Toloxatone MAOA;MAOA DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways 1651:[DB09245 DB07172] DB09245|Toloxatone MAOA;MAOA DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways 1652:[DB09245 DB01070] DB09245|Toloxatone MAOA;MAOA DB01070|Dihydrotachysterol VDR common genes common pathways 1653:[DB09245 DB05505] DB09245|Toloxatone MAOA;MAOA DB05505|NM-702 TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process TBXAS1;MAOA 1654:[DB09245 DB02763] DB09245|Toloxatone MAOA;MAOA DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways 1655:[DB09245 DB08847] DB09245|Toloxatone MAOA;MAOA DB08847|Hydroxyproline SLC36A1 common genes common pathways 1656:[DB09245 DB02383] DB09245|Toloxatone MAOA;MAOA DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways GO:0055114| oxidation-reduction process AKR1A1;AKR1B1;AKR1B10;MAOA 1657:[DB09245 DB11607] DB09245|Toloxatone MAOA;MAOA DB11607|Efmoroctocog alfa VWF common genes common pathways 1658:[DB09245 DB04825] DB09245|Toloxatone MAOA;MAOA DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1659:[DB09245 DB00152] DB09245|Toloxatone MAOA;MAOA DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0055114| oxidation-reduction process CYP4B1;MAOA 1660:[DB09245 DB04964] DB09245|Toloxatone MAOA;MAOA DB04964|Oregovomab MUC16 common genes common pathways 1661:[DB09245 DB05476] DB09245|Toloxatone MAOA;MAOA DB05476|WX-UK1 PLAUR common genes common pathways 1662:[DB09245 DB09029] DB09245|Toloxatone MAOA;MAOA DB09029|Secukinumab IL17A common genes common pathways 1663:[DB09245 DB00097] DB09245|Toloxatone MAOA;MAOA DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways 1664:[DB09245 DB00836] DB09245|Toloxatone MAOA;MAOA DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP2B6;MAOA 1665:[DB09245 DB00210] DB09245|Toloxatone MAOA;MAOA DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOA 1666:[DB09245 DB05421] DB09245|Toloxatone MAOA;MAOA DB05421|CP-122721 TACR1 common genes common pathways 1667:[DB09245 DB12332] DB09245|Toloxatone MAOA;MAOA DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;ABCC4;CYP3A5;CYP2C19;CYP2C8;CYP2D6;MAOA;CYP1A2;CYP3A7;CYP2C9;CYP3A4 1668:[DB09245 DB01155] DB09245|Toloxatone MAOA;MAOA DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1669:[DB09245 DB05431] DB09245|Toloxatone MAOA;MAOA DB05431|MLN-977 ALOX5 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;MAOA 1670:[DB09245 DB02998] DB09245|Toloxatone MAOA;MAOA DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways 1671:[DB09245 DB14635] DB09245|Toloxatone MAOA;MAOA DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP3A4;CYP1A2;MAOA;CYP2D6;CBR1 1672:[DB09245 DB00877] DB09245|Toloxatone MAOA;MAOA DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;MAOA;CYP3A7 1673:[DB09245 DB11712] DB09245|Toloxatone MAOA;MAOA DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP3A4 1674:[DB09245 DB02813] DB09245|Toloxatone MAOA;MAOA DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways 1675:[DB09245 DB04318] DB09245|Toloxatone MAOA;MAOA DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways 1676:[DB09245 DB02142] DB09245|Toloxatone MAOA;MAOA DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways 1677:[DB09245 DB12334] DB09245|Toloxatone MAOA;MAOA DB12334|Milataxel TUBB1;TUBB common genes common pathways 1678:[DB09245 DB06157] DB09245|Toloxatone MAOA;MAOA DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways 1679:[DB09245 DB07462] DB09245|Toloxatone MAOA;MAOA DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0006584| catecholamine metabolic process MAOA;COMT GO:0042420| dopamine catabolic process COMT;MAOA GO:0042135| neurotransmitter catabolic process COMT;MAOA 1680:[DB09245 DB09303] DB09245|Toloxatone MAOA;MAOA DB09303|Evolocumab PCSK9 common genes common pathways 1681:[DB09245 DB01284] DB09245|Toloxatone MAOA;MAOA DB01284|Tetracosactide MC2R common genes common pathways 1682:[DB09245 DB05913] DB09245|Toloxatone MAOA;MAOA DB05913|OSI-930 KIT;FLT1 common genes common pathways 1683:[DB09245 DB06124] DB09245|Toloxatone MAOA;MAOA DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways 1684:[DB09245 DB12200] DB09245|Toloxatone MAOA;MAOA DB12200|Tivantinib MET common genes common pathways 1685:[DB09245 DB06366] DB09245|Toloxatone MAOA;MAOA DB06366|Pertuzumab ERBB2 common genes common pathways 1686:[DB09245 DB04590] DB09245|Toloxatone MAOA;MAOA DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways 1687:[DB09245 DB05668] DB09245|Toloxatone MAOA;MAOA DB05668|Palifosfamide DNMT1 common genes common pathways 1688:[DB09245 DB04758] DB09245|Toloxatone MAOA;MAOA DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways 1689:[DB09245 DB06101] DB09245|Toloxatone MAOA;MAOA DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways 1690:[DB09245 DB04461] DB09245|Toloxatone MAOA;MAOA DB04461|Coproporphyrinogen III UROD common genes common pathways 1691:[DB09245 DB07039] DB09245|Toloxatone MAOA;MAOA DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways 1692:[DB09245 DB11059] DB09245|Toloxatone MAOA;MAOA DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways 1693:[DB09245 DB03403] DB09245|Toloxatone MAOA;MAOA DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 1694:[DB09245 DB00685] DB09245|Toloxatone MAOA;MAOA DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 1695:[DB09245 DB06237] DB09245|Toloxatone MAOA;MAOA DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1696:[DB09245 DB08497] DB09245|Toloxatone MAOA;MAOA DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways 1697:[DB09245 DB08155] DB09245|Toloxatone MAOA;MAOA DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways 1698:[DB09245 DB07428] DB09245|Toloxatone MAOA;MAOA DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 1699:[DB09245 DB04074] DB09245|Toloxatone MAOA;MAOA DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 1700:[DB09245 DB03239] DB09245|Toloxatone MAOA;MAOA DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways 1701:[DB09245 DB04843] DB09245|Toloxatone MAOA;MAOA DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways 1702:[DB09245 DB07067] DB09245|Toloxatone MAOA;MAOA DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways 1703:[DB09245 DB05191] DB09245|Toloxatone MAOA;MAOA DB05191|Atl146e ADORA2A common genes common pathways 1704:[DB09245 DB01834] DB09245|Toloxatone MAOA;MAOA DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways 1705:[DB09245 DB00859] DB09245|Toloxatone MAOA;MAOA DB00859|Penicillamine SLCO1B1 common genes common pathways 1706:[DB09245 DB12458] DB09245|Toloxatone MAOA;MAOA DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways 1707:[DB09245 DB11703] DB09245|Toloxatone MAOA;MAOA DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;MAOA;CYP3A7 1708:[DB09245 DB00655] DB09245|Toloxatone MAOA;MAOA DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;MAOA;CYP1A2;CYP4A11;CYP2B6;CYP3A4;CYP19A1;CYP2C9;CYP1A1;CYP2E1 1709:[DB09245 DB00902] DB09245|Toloxatone MAOA;MAOA DB00902|Methdilazine HRH1 common genes common pathways 1710:[DB09245 DB05087] DB09245|Toloxatone MAOA;MAOA DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways 1711:[DB09245 DB05351] DB09245|Toloxatone MAOA;MAOA DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;MAOA 1712:[DB09245 DB14642] DB09245|Toloxatone MAOA;MAOA DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways 1713:[DB09245 DB04865] DB09245|Toloxatone MAOA;MAOA DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 1714:[DB09245 DB06536] DB09245|Toloxatone MAOA;MAOA DB06536|Tesaglitazar PPARA;PPARG common genes common pathways 1715:[DB09245 DB00845] DB09245|Toloxatone MAOA;MAOA DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1716:[DB09245 DB09065] DB09245|Toloxatone MAOA;MAOA DB09065|Cobicistat CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP3A43;CYP3A4;MAOA;CYP3A7 1717:[DB09245 DB08760] DB09245|Toloxatone MAOA;MAOA DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways 1718:[DB09245 DB04889] DB09245|Toloxatone MAOA;MAOA DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOA;MAOB;CYP2D6 GO:0042420| dopamine catabolic process MAOB;MAOA GO:0042135| neurotransmitter catabolic process MAOA;MAOB 1719:[DB09245 DB04187] DB09245|Toloxatone MAOA;MAOA DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways 1720:[DB09245 DB01569] DB09245|Toloxatone MAOA;MAOA DB01569|Formebolone HSD11B2 common genes common pathways GO:0055114| oxidation-reduction process HSD11B2;MAOA 1721:[DB09245 DB05434] DB09245|Toloxatone MAOA;MAOA DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways 1722:[DB09245 DB01008] DB09245|Toloxatone MAOA;MAOA DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1723:[DB09245 DB00517] DB09245|Toloxatone MAOA;MAOA DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways 1724:[DB09245 DB08838] DB09245|Toloxatone MAOA;MAOA DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1725:[DB09245 DB00131] DB09245|Toloxatone MAOA;MAOA DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways 1726:[DB09245 DB04066] DB09245|Toloxatone MAOA;MAOA DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways GO:0055114| oxidation-reduction process PTGR1;MAOA 1727:[DB09245 DB09282] DB09245|Toloxatone MAOA;MAOA DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 1728:[DB09245 DB00630] DB09245|Toloxatone MAOA;MAOA DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways 1729:[DB09245 DB08326] DB09245|Toloxatone MAOA;MAOA DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways 1730:[DB09245 DB08846] DB09245|Toloxatone MAOA;MAOA DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A1;CYP2E1;SQLE 1731:[DB09245 DB03349] DB09245|Toloxatone MAOA;MAOA DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways 1732:[DB09245 DB11094] DB09245|Toloxatone MAOA;MAOA DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP27B1;CYP2R1;MAOA 1733:[DB09245 DB05418] DB09245|Toloxatone MAOA;MAOA DB05418|GW 597599 TACR1 common genes common pathways 1734:[DB09245 DB05218] DB09245|Toloxatone MAOA;MAOA DB05218|PN0621 TNF common genes common pathways 1735:[DB09245 DB07976] DB09245|Toloxatone MAOA;MAOA DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1736:[DB09245 DB09053] DB09245|Toloxatone MAOA;MAOA DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6;CYP3A5 1737:[DB09245 DB00276] DB09245|Toloxatone MAOA;MAOA DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways 1738:[DB09245 DB02109] DB09245|Toloxatone MAOA;MAOA DB02109|Hadacidin purA;ADSSL1 common genes common pathways 1739:[DB09245 DB03415] DB09245|Toloxatone MAOA;MAOA DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways GO:0055114| oxidation-reduction process MAOA;ACADM 1740:[DB09245 DB06999] DB09245|Toloxatone MAOA;MAOA DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways 1741:[DB09245 DB04883] DB09245|Toloxatone MAOA;MAOA DB04883|Darusentan EDNRA common genes common pathways 1742:[DB09245 DB00878] DB09245|Toloxatone MAOA;MAOA DB00878|Chlorhexidine HNMT;cat common genes common pathways 1743:[DB09245 DB11586] DB09245|Toloxatone MAOA;MAOA DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP3A5;CYP2C19;CYP2D6;MAOA;CYP3A7;CYP2C9;CYP3A4;CYP2B6;CYP2A6 1744:[DB09245 DB07621] DB09245|Toloxatone MAOA;MAOA DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;MAOA 1745:[DB09245 DB11429] DB09245|Toloxatone MAOA;MAOA DB11429|Mibolerone AR common genes common pathways 1746:[DB09245 DB00675] DB09245|Toloxatone MAOA;MAOA DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP3A7;MAOA;CYP2A6;CYP2B6;FMO3;CYP19A1;CYP3A4;FMO1;CYP2E1;CYP2C9;CYP1A1 GO:0006584| catecholamine metabolic process SULT1A1;MAOA 1747:[DB09245 DB14065] DB09245|Toloxatone MAOA;MAOA DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1748:[DB09245 DB05466] DB09245|Toloxatone MAOA;MAOA DB05466|R673 TACR1 common genes common pathways 1749:[DB09245 DB05752] DB09245|Toloxatone MAOA;MAOA DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 1750:[DB09245 DB04805] DB09245|Toloxatone MAOA;MAOA DB04805|Virginiamycin S1 RPL37 common genes common pathways 1751:[DB09245 DB06460] DB09245|Toloxatone MAOA;MAOA DB06460|Enrasentan EDNRA;EDNRB common genes common pathways 1752:[DB09245 DB01019] DB09245|Toloxatone MAOA;MAOA DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways 1753:[DB09245 DB13800] DB09245|Toloxatone MAOA;MAOA DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways 1754:[DB09245 DB04527] DB09245|Toloxatone MAOA;MAOA DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways 1755:[DB09245 DB08613] DB09245|Toloxatone MAOA;MAOA DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways 1756:[DB09245 DB01496] DB09245|Toloxatone MAOA;MAOA DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 1757:[DB09245 DB05194] DB09245|Toloxatone MAOA;MAOA DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways 1758:[DB09245 DB11637] DB09245|Toloxatone MAOA;MAOA DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1759:[DB09245 DB13994] DB09245|Toloxatone MAOA;MAOA DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 1760:[DB09245 DB02670] DB09245|Toloxatone MAOA;MAOA DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways 1761:[DB09245 DB06925] DB09245|Toloxatone MAOA;MAOA DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways 1762:[DB09245 DB08502] DB09245|Toloxatone MAOA;MAOA DB08502|Capravirine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1763:[DB09245 DB00989] DB09245|Toloxatone MAOA;MAOA DB00989|Rivastigmine ACHE;BCHE;CYP3A4 common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE GO:0055114| oxidation-reduction process CYP3A4;MAOA 1764:[DB09245 DB01548] DB09245|Toloxatone MAOA;MAOA DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways 1765:[DB09245 DB11256] DB09245|Toloxatone MAOA;MAOA DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways 1766:[DB09245 DB11064] DB09245|Toloxatone MAOA;MAOA DB11064|Homosalate PGR;AR;ESR1 common genes common pathways 1767:[DB09245 DB05044] DB09245|Toloxatone MAOA;MAOA DB05044|PSN357 PYGL common genes common pathways 1768:[DB09245 DB07720] DB09245|Toloxatone MAOA;MAOA DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways 1769:[DB09245 DB07694] DB09245|Toloxatone MAOA;MAOA DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways 1770:[DB09245 DB05201] DB09245|Toloxatone MAOA;MAOA DB05201|V24343 CNR1 common genes common pathways 1771:[DB09245 DB05451] DB09245|Toloxatone MAOA;MAOA DB05451|P54 NFKB2;NFKB1 common genes common pathways 1772:[DB09245 DB03566] DB09245|Toloxatone MAOA;MAOA DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;TXNRD1 1773:[DB09245 DB09331] DB09245|Toloxatone MAOA;MAOA DB09331|Daratumumab CD38 common genes common pathways 1774:[DB09245 DB06111] DB09245|Toloxatone MAOA;MAOA DB06111|AB192 MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;MAOA 1775:[DB09245 DB00008] DB09245|Toloxatone MAOA;MAOA DB00008|Peginterferon alfa-2a IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 1776:[DB09245 DB01074] DB09245|Toloxatone MAOA;MAOA DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA;CYP2B6;CYP3A4 1777:[DB09245 DB04915] DB09245|Toloxatone MAOA;MAOA DB04915|Idronoxil ENOX2 common genes common pathways GO:0055114| oxidation-reduction process ENOX2;MAOA 1778:[DB09245 DB05091] DB09245|Toloxatone MAOA;MAOA DB05091|M0002 AVPR2 common genes common pathways 1779:[DB09245 DB06595] DB09245|Toloxatone MAOA;MAOA DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP3A43;CYP2C9;CYP2E1;CYP3A4;CYP2B6;MAOA;CYP1A2;CYP3A7 1780:[DB09245 DB08172] DB09245|Toloxatone MAOA;MAOA DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 1781:[DB09245 DB01962] DB09245|Toloxatone MAOA;MAOA DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways 1782:[DB09245 DB01835] DB09245|Toloxatone MAOA;MAOA DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 1783:[DB09245 DB03419] DB09245|Toloxatone MAOA;MAOA DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0055114| oxidation-reduction process DPYD;MAOA 1784:[DB09245 DB01296] DB09245|Toloxatone MAOA;MAOA DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MAOA;CYP2C19 1785:[DB09245 DB12866] DB09245|Toloxatone MAOA;MAOA DB12866|Pradigastat SLC22A8 common genes common pathways 1786:[DB09245 DB02974] DB09245|Toloxatone MAOA;MAOA DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;MAOA 1787:[DB09245 DB04674] DB09245|Toloxatone MAOA;MAOA DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0055114| oxidation-reduction process AKR1C1;MAOA 1788:[DB09245 DB13150] DB09245|Toloxatone MAOA;MAOA DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways 1789:[DB09245 DB00521] DB09245|Toloxatone MAOA;MAOA DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 1790:[DB09245 DB06842] DB09245|Toloxatone MAOA;MAOA DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways 1791:[DB09245 DB00549] DB09245|Toloxatone MAOA;MAOA DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2E1;CYP3A4;MAOA;CYP1A2;CYP2C8;CYP2C19;PTGS1 1792:[DB09245 DB00531] DB09245|Toloxatone MAOA;MAOA DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2A6;CYP2C9;CYP3A4;MAOA;CYP2C18;CYP2C19;CYP2C8;CYP3A5 1793:[DB09245 DB05419] DB09245|Toloxatone MAOA;MAOA DB05419|ADX-10061 CALY common genes common pathways 1794:[DB09245 DB07695] DB09245|Toloxatone MAOA;MAOA DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways 1795:[DB09245 DB07851] DB09245|Toloxatone MAOA;MAOA DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways 1796:[DB09245 DB09296] DB09245|Toloxatone MAOA;MAOA DB09296|Ombitasvir CYP2C8;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA 1797:[DB09245 DB02773] DB09245|Toloxatone MAOA;MAOA DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1 1798:[DB09245 DB06769] DB09245|Toloxatone MAOA;MAOA DB06769|Bendamustine CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 1799:[DB09245 DB05022] DB09245|Toloxatone MAOA;MAOA DB05022|Amonafide TOP2A;TOP2B common genes common pathways 1800:[DB09245 DB00192] DB09245|Toloxatone MAOA;MAOA DB00192|Indecainide SCN5A common genes common pathways 1801:[DB09245 DB00534] DB09245|Toloxatone MAOA;MAOA DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0042135| neurotransmitter catabolic process ALDH5A1;MAOA GO:0055114| oxidation-reduction process MAOA;ALDH5A1 1802:[DB09245 DB08299] DB09245|Toloxatone MAOA;MAOA DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways 1803:[DB09245 DB05210] DB09245|Toloxatone MAOA;MAOA DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways 1804:[DB09245 DB00963] DB09245|Toloxatone MAOA;MAOA DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;MAOA;PTGS2 1805:[DB09245 DB00396] DB09245|Toloxatone MAOA;MAOA DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP3A4;CYP2A6;MAOA;CYP3A7 1806:[DB09245 DB05305] DB09245|Toloxatone MAOA;MAOA DB05305|Cintredekin Besudotox IL13 common genes common pathways 1807:[DB09245 DB06138] DB09245|Toloxatone MAOA;MAOA DB06138|IRL-1620 EDNRB common genes common pathways 1808:[DB09245 DB07963] DB09245|Toloxatone MAOA;MAOA DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways 1809:[DB09245 DB11491] DB09245|Toloxatone MAOA;MAOA DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1810:[DB09245 DB02635] DB09245|Toloxatone MAOA;MAOA DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways 1811:[DB09245 DB06751] DB09245|Toloxatone MAOA;MAOA DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways 1812:[DB09245 DB04926] DB09245|Toloxatone MAOA;MAOA DB04926|Neramexane GRIN3A common genes common pathways 1813:[DB09245 DB07132] DB09245|Toloxatone MAOA;MAOA DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways 1814:[DB09245 DB01650] DB09245|Toloxatone MAOA;MAOA DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways 1815:[DB09245 DB05521] DB09245|Toloxatone MAOA;MAOA DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;MAOA 1816:[DB09245 DB01257] DB09245|Toloxatone MAOA;MAOA DB01257|Eculizumab C5 common genes common pathways 1817:[DB09245 DB02825] DB09245|Toloxatone MAOA;MAOA DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 1818:[DB09245 DB02854] DB09245|Toloxatone MAOA;MAOA DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0055114| oxidation-reduction process HSD17B11;MAOA 1819:[DB09245 DB06534] DB09245|Toloxatone MAOA;MAOA DB06534|Thrombopoietin MPL common genes common pathways 1820:[DB09245 DB05166] DB09245|Toloxatone MAOA;MAOA DB05166|APD668 GPR119 common genes common pathways 1821:[DB09245 DB12035] DB09245|Toloxatone MAOA;MAOA DB12035|Sarecycline ABCB1 common genes common pathways 1822:[DB09245 DB08827] DB09245|Toloxatone MAOA;MAOA DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1823:[DB09245 DB12077] DB09245|Toloxatone MAOA;MAOA DB12077|Urelumab TNFRSF9 common genes common pathways 1824:[DB09245 DB06274] DB09245|Toloxatone MAOA;MAOA DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways 1825:[DB09245 DB11431] DB09245|Toloxatone MAOA;MAOA DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A7;CYP3A4;CYP3A43;CYP3A5 1826:[DB09245 DB05688] DB09245|Toloxatone MAOA;MAOA DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways 1827:[DB09245 DB04958] DB09245|Toloxatone MAOA;MAOA DB04958|Epratuzumab CD22 common genes common pathways 1828:[DB09245 DB04166] DB09245|Toloxatone MAOA;MAOA DB04166|Anthranilic acid IL4I1;DAO common genes common pathways GO:0055114| oxidation-reduction process MAOA;IL4I1;DAO 1829:[DB09245 DB12890] DB09245|Toloxatone MAOA;MAOA DB12890|Dihydrexidine DRD1 common genes common pathways 1830:[DB09245 DB00130] DB09245|Toloxatone MAOA;MAOA DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways 1831:[DB09245 DB14069] DB09245|Toloxatone MAOA;MAOA DB14069|ONT-093 ABCB1 common genes common pathways 1832:[DB09245 DB07427] DB09245|Toloxatone MAOA;MAOA DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 1833:[DB09245 DB00117] DB09245|Toloxatone MAOA;MAOA DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways 1834:[DB09245 DB04472] DB09245|Toloxatone MAOA;MAOA DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways 1835:[DB09245 DB06749] DB09245|Toloxatone MAOA;MAOA DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways 1836:[DB09245 DB00978] DB09245|Toloxatone MAOA;MAOA DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 1837:[DB09245 DB06714] DB09245|Toloxatone MAOA;MAOA DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways 1838:[DB09245 DB06603] DB09245|Toloxatone MAOA;MAOA DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6 1839:[DB09245 DB04602] DB09245|Toloxatone MAOA;MAOA DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 1840:[DB09245 DB01561] DB09245|Toloxatone MAOA;MAOA DB01561|Androstanedione HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;HSD17B1 1841:[DB09245 DB05290] DB09245|Toloxatone MAOA;MAOA DB05290|SPP 301 EDNRA common genes common pathways 1842:[DB09245 DB09142] DB09245|Toloxatone MAOA;MAOA DB09142|Sincalide SLCO1B3 common genes common pathways 1843:[DB09245 DB06342] DB09245|Toloxatone MAOA;MAOA DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1844:[DB09245 DB04299] DB09245|Toloxatone MAOA;MAOA DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways 1845:[DB09245 DB03807] DB09245|Toloxatone MAOA;MAOA DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways 1846:[DB09245 DB07194] DB09245|Toloxatone MAOA;MAOA DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways 1847:[DB09245 DB09108] DB09245|Toloxatone MAOA;MAOA DB09108|Simoctocog Alfa VWF common genes common pathways 1848:[DB09245 DB07423] DB09245|Toloxatone MAOA;MAOA DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways 1849:[DB09245 DB02323] DB09245|Toloxatone MAOA;MAOA DB02323|EM-1745 HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;HSD17B1 1850:[DB09245 DB00305] DB09245|Toloxatone MAOA;MAOA DB00305|Mitomycin POR common genes common pathways GO:0055114| oxidation-reduction process POR;MAOA 1851:[DB09245 DB02542] DB09245|Toloxatone MAOA;MAOA DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways 1852:[DB09245 DB01047] DB09245|Toloxatone MAOA;MAOA DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1853:[DB09245 DB04464] DB09245|Toloxatone MAOA;MAOA DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0055114| oxidation-reduction process MT-CO1;MAOA;MT-ND1;MT-CO2 1854:[DB09245 DB00619] DB09245|Toloxatone MAOA;MAOA DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;MAOA;CYP3A4;CYP2C9 1855:[DB09245 DB02796] DB09245|Toloxatone MAOA;MAOA DB02796|9-Deazainosine PNP common genes common pathways 1856:[DB09245 DB02162] DB09245|Toloxatone MAOA;MAOA DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways 1857:[DB09245 DB01263] DB09245|Toloxatone MAOA;MAOA DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1858:[DB09245 DB08374] DB09245|Toloxatone MAOA;MAOA DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways 1859:[DB09245 DB04260] DB09245|Toloxatone MAOA;MAOA DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways 1860:[DB09245 DB08357] DB09245|Toloxatone MAOA;MAOA DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 1861:[DB09245 DB08904] DB09245|Toloxatone MAOA;MAOA DB08904|Certolizumab pegol TNF common genes common pathways 1862:[DB09245 DB03523] DB09245|Toloxatone MAOA;MAOA DB03523|Brequinar DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1863:[DB09245 DB05941] DB09245|Toloxatone MAOA;MAOA DB05941|Leronlimab CCR5 common genes common pathways 1864:[DB09245 DB01590] DB09245|Toloxatone MAOA;MAOA DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1865:[DB09245 DB00036] DB09245|Toloxatone MAOA;MAOA DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways 1866:[DB09245 DB07567] DB09245|Toloxatone MAOA;MAOA DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways 1867:[DB09245 DB03660] DB09245|Toloxatone MAOA;MAOA DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways 1868:[DB09245 DB06916] DB09245|Toloxatone MAOA;MAOA DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 1869:[DB09245 DB03060] DB09245|Toloxatone MAOA;MAOA DB03060|Sri-9662 DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 1870:[DB09245 DB01571] DB09245|Toloxatone MAOA;MAOA DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 1871:[DB09245 DB00340] DB09245|Toloxatone MAOA;MAOA DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways 1872:[DB09245 DB08737] DB09245|Toloxatone MAOA;MAOA DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways 1873:[DB09245 DB04343] DB09245|Toloxatone MAOA;MAOA DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways 1874:[DB09245 DB08820] DB09245|Toloxatone MAOA;MAOA DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A5 1875:[DB09245 DB04478] DB09245|Toloxatone MAOA;MAOA DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0055114| oxidation-reduction process MAOA;SORD 1876:[DB09245 DB00324] DB09245|Toloxatone MAOA;MAOA DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1877:[DB09245 DB07380] DB09245|Toloxatone MAOA;MAOA DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 1878:[DB09245 DB03341] DB09245|Toloxatone MAOA;MAOA DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways 1879:[DB09245 DB04938] DB09245|Toloxatone MAOA;MAOA DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2B6;CYP2C9;CYP3A4;CYP2C19;CYP2D6 1880:[DB09245 DB05072] DB09245|Toloxatone MAOA;MAOA DB05072|AV608 TACR1 common genes common pathways 1881:[DB09245 DB13878] DB09245|Toloxatone MAOA;MAOA DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;MAOA;CYP3A5;CYP3A43 1882:[DB09245 DB02648] DB09245|Toloxatone MAOA;MAOA DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways 1883:[DB09245 DB02583] DB09245|Toloxatone MAOA;MAOA DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 1884:[DB09245 DB04230] DB09245|Toloxatone MAOA;MAOA DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 1885:[DB09245 DB02078] DB09245|Toloxatone MAOA;MAOA DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways 1886:[DB09245 DB13961] DB09245|Toloxatone MAOA;MAOA DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;PTGS2 1887:[DB09245 DB00444] DB09245|Toloxatone MAOA;MAOA DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9;CYP3A4;CYP2C19;CYP3A5 1888:[DB09245 DB01942] DB09245|Toloxatone MAOA;MAOA DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CTBP1;GPHN;HMOX1;NOS1 1889:[DB09245 DB01098] DB09245|Toloxatone MAOA;MAOA DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;CYP2C19;CYP3A5;HMGCR;MAOA;CYP2C9;CYP3A4 1890:[DB09245 DB08447] DB09245|Toloxatone MAOA;MAOA DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways 1891:[DB09245 DB08258] DB09245|Toloxatone MAOA;MAOA DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways 1892:[DB09245 DB01007] DB09245|Toloxatone MAOA;MAOA DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP19A1;MAOA;CYP51A1;CYP2C8;CYP2C19 1893:[DB09245 DB00513] DB09245|Toloxatone MAOA;MAOA DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways GO:0055114| oxidation-reduction process AOX1;MAOA 1894:[DB09245 DB07666] DB09245|Toloxatone MAOA;MAOA DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways 1895:[DB09245 DB04237] DB09245|Toloxatone MAOA;MAOA DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways 1896:[DB09245 DB03115] DB09245|Toloxatone MAOA;MAOA DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways 1897:[DB09245 DB02489] DB09245|Toloxatone MAOA;MAOA DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 1898:[DB09245 DB13746] DB09245|Toloxatone MAOA;MAOA DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C9;CYP2C8;CYP2C19 1899:[DB09245 DB01410] DB09245|Toloxatone MAOA;MAOA DB01410|Ciclesonide NR3C1;CYP3A4;CYP2D6;CES1;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA;CYP3A4 1900:[DB09245 DB03802] DB09245|Toloxatone MAOA;MAOA DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways 1901:[DB09245 DB04365] DB09245|Toloxatone MAOA;MAOA DB04365|Arecoline CHRM1;CHRM3 common genes common pathways 1902:[DB09245 DB01593] DB09245|Toloxatone MAOA;MAOA DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0055114| oxidation-reduction process CP;CCS;PRDX1;ADH1C;PDIA3;MAOA;P4HB;GAPDHS;SOD1 1903:[DB09245 DB00075] DB09245|Toloxatone MAOA;MAOA DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 1904:[DB09245 DB09063] DB09245|Toloxatone MAOA;MAOA DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C9 1905:[DB09245 DB13893] DB09245|Toloxatone MAOA;MAOA DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways 1906:[DB09245 DB08387] DB09245|Toloxatone MAOA;MAOA DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 1907:[DB09245 DB00607] DB09245|Toloxatone MAOA;MAOA DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP1A2 1908:[DB09245 DB05932] DB09245|Toloxatone MAOA;MAOA DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways 1909:[DB09245 DB06786] DB09245|Toloxatone MAOA;MAOA DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1910:[DB09245 DB13141] DB09245|Toloxatone MAOA;MAOA DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;CYP3A4;CYP3A43;CYP3A5 1911:[DB09245 DB13867] DB09245|Toloxatone MAOA;MAOA DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA 1912:[DB09245 DB00134] DB09245|Toloxatone MAOA;MAOA DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process MTRR;MSRB1;MSRA;MAOA;MTHFR;MSRB2 1913:[DB09245 DB05895] DB09245|Toloxatone MAOA;MAOA DB05895|HGS-TR2J TNFRSF10B common genes common pathways 1914:[DB09245 DB02943] DB09245|Toloxatone MAOA;MAOA DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways 1915:[DB09245 DB07280] DB09245|Toloxatone MAOA;MAOA DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 1916:[DB09245 DB03182] DB09245|Toloxatone MAOA;MAOA DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 1917:[DB09245 DB00342] DB09245|Toloxatone MAOA;MAOA DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A5;CYP3A4;CYP2J2;CYP3A7;MAOA 1918:[DB09245 DB02021] DB09245|Toloxatone MAOA;MAOA DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways GO:0055114| oxidation-reduction process AKR1B10;MAOA;AKR1B1 1919:[DB09245 DB04616] DB09245|Toloxatone MAOA;MAOA DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 1920:[DB09245 DB13923] DB09245|Toloxatone MAOA;MAOA DB13923|Emicizumab F9;F10 common genes common pathways 1921:[DB09245 DB01220] DB09245|Toloxatone MAOA;MAOA DB01220|Rifaximin rpoB;NR1I2;CYP3A4;CYP2C19;CYP2C8;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6;CYP2C19;CYP2C8 1922:[DB09245 DB14061] DB09245|Toloxatone MAOA;MAOA DB14061|Hycanthone ABCB1 common genes common pathways 1923:[DB09245 DB00112] DB09245|Toloxatone MAOA;MAOA DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 1924:[DB09245 DB07840] DB09245|Toloxatone MAOA;MAOA DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways 1925:[DB09245 DB05235] DB09245|Toloxatone MAOA;MAOA DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0055114| oxidation-reduction process CRYM;MAOA 1926:[DB09245 DB08164] DB09245|Toloxatone MAOA;MAOA DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways 1927:[DB09245 DB04539] DB09245|Toloxatone MAOA;MAOA DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1 1928:[DB09245 DB00823] DB09245|Toloxatone MAOA;MAOA DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1929:[DB09245 DB07908] DB09245|Toloxatone MAOA;MAOA DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways 1930:[DB09245 DB06586] DB09245|Toloxatone MAOA;MAOA DB06586|Cetilistat PNLIP common genes common pathways 1931:[DB09245 DB00174] DB09245|Toloxatone MAOA;MAOA DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways 1932:[DB09245 DB04873] DB09245|Toloxatone MAOA;MAOA DB04873|Piboserod HTR4 common genes common pathways 1933:[DB09245 DB07046] DB09245|Toloxatone MAOA;MAOA DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways 1934:[DB09245 DB01031] DB09245|Toloxatone MAOA;MAOA DB01031|Ethinamate CA1;CA2 common genes common pathways 1935:[DB09245 DB11937] DB09245|Toloxatone MAOA;MAOA DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways 1936:[DB09245 DB06159] DB09245|Toloxatone MAOA;MAOA DB06159|Rubitecan TOP1 common genes common pathways 1937:[DB09245 DB05501] DB09245|Toloxatone MAOA;MAOA DB05501|AMD-070 CXCR4;CCR5 common genes common pathways 1938:[DB09245 DB03839] DB09245|Toloxatone MAOA;MAOA DB03839|D-Tyrosine SLC16A10 common genes common pathways 1939:[DB09245 DB06862] DB09245|Toloxatone MAOA;MAOA DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways 1940:[DB09245 DB06492] DB09245|Toloxatone MAOA;MAOA DB06492|Mirococept C3 common genes common pathways 1941:[DB09245 DB01426] DB09245|Toloxatone MAOA;MAOA DB01426|Ajmaline SCN5A;ORM1 common genes common pathways 1942:[DB09245 DB12520] DB09245|Toloxatone MAOA;MAOA DB12520|Plozalizumab CCR2 common genes common pathways 1943:[DB09245 DB07558] DB09245|Toloxatone MAOA;MAOA DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways 1944:[DB09245 DB08830] DB09245|Toloxatone MAOA;MAOA DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways 1945:[DB09245 DB07958] DB09245|Toloxatone MAOA;MAOA DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways 1946:[DB09245 DB00462] DB09245|Toloxatone MAOA;MAOA DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways 1947:[DB09245 DB04850] DB09245|Toloxatone MAOA;MAOA DB04850|Posizolid MAOA;SLCO1B1 common genes MAOA common pathways GO:0006584| catecholamine metabolic process MAOA GO:0042420| dopamine catabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0006576| cellular biogenic amine metabolic process MAOA GO:0055114| oxidation-reduction process MAOA 1948:[DB09245 DB05142] DB09245|Toloxatone MAOA;MAOA DB05142|ND7001 PDE2A;PDE2A common genes common pathways 1949:[DB09245 DB06266] DB09245|Toloxatone MAOA;MAOA DB06266|Lonidamine CFTR;HK1 common genes common pathways 1950:[DB09245 DB04858] DB09245|Toloxatone MAOA;MAOA DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 1951:[DB09245 DB03348] DB09245|Toloxatone MAOA;MAOA DB03348|Huperzine B ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 1952:[DB09245 DB05930] DB09245|Toloxatone MAOA;MAOA DB05930|SB-559448 MPL common genes common pathways 1953:[DB09245 DB01864] DB09245|Toloxatone MAOA;MAOA DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways 1954:[DB09245 DB11672] DB09245|Toloxatone MAOA;MAOA DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA;CYP2B6;CYP3A4;CYP2C9;CYP2D6;CBR1 1955:[DB09245 DB05457] DB09245|Toloxatone MAOA;MAOA DB05457|OSI-7904L TYMS common genes common pathways 1956:[DB09245 DB04489] DB09245|Toloxatone MAOA;MAOA DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 1957:[DB09245 DB00394] DB09245|Toloxatone MAOA;MAOA DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP3A4 1958:[DB09245 DB05678] DB09245|Toloxatone MAOA;MAOA DB05678|SLx-4090 MTTP common genes common pathways 1959:[DB09245 DB03283] DB09245|Toloxatone MAOA;MAOA DB03283|beta-L-fucose ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 1960:[DB09245 DB02391] DB09245|Toloxatone MAOA;MAOA DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways 1961:[DB09245 DB05478] DB09245|Toloxatone MAOA;MAOA DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1962:[DB09245 DB03214] DB09245|Toloxatone MAOA;MAOA DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;IL4I1 1963:[DB09245 DB06987] DB09245|Toloxatone MAOA;MAOA DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways 1964:[DB09245 DB11623] DB09245|Toloxatone MAOA;MAOA DB11623|Candoxatrilat MME common genes common pathways 1965:[DB09245 DB02299] DB09245|Toloxatone MAOA;MAOA DB02299|Arginineamide KCNA4 common genes common pathways 1966:[DB09245 DB08799] DB09245|Toloxatone MAOA;MAOA DB08799|Antazoline HRH1 common genes common pathways 1967:[DB09245 DB03934] DB09245|Toloxatone MAOA;MAOA DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways GO:0055114| oxidation-reduction process CYCS;MAOA 1968:[DB09245 DB06081] DB09245|Toloxatone MAOA;MAOA DB06081|Caplacizumab VWF common genes common pathways 1969:[DB09245 DB12637] DB09245|Toloxatone MAOA;MAOA DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways 1970:[DB09245 DB07000] DB09245|Toloxatone MAOA;MAOA DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways 1971:[DB09245 DB07070] DB09245|Toloxatone MAOA;MAOA DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways 1972:[DB09245 DB05447] DB09245|Toloxatone MAOA;MAOA DB05447|AVI-4557 HNF4A common genes common pathways 1973:[DB09245 DB01190] DB09245|Toloxatone MAOA;MAOA DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1974:[DB09245 DB05107] DB09245|Toloxatone MAOA;MAOA DB05107|16-Bromoepiandrosterone G6PD common genes common pathways GO:0055114| oxidation-reduction process G6PD;MAOA 1975:[DB09245 DB01990] DB09245|Toloxatone MAOA;MAOA DB01990|Cholesterol sulfate RORA common genes common pathways 1976:[DB09245 DB03682] DB09245|Toloxatone MAOA;MAOA DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways 1977:[DB09245 DB02868] DB09245|Toloxatone MAOA;MAOA DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways 1978:[DB09245 DB05243] DB09245|Toloxatone MAOA;MAOA DB05243|XL019 JAK2 common genes common pathways 1979:[DB09245 DB11692] DB09245|Toloxatone MAOA;MAOA DB11692|Pavinetant TACR3 common genes common pathways 1980:[DB09245 DB01404] DB09245|Toloxatone MAOA;MAOA DB01404|Ginseng IL6;PTGS2;AHR common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 1981:[DB09245 DB08006] DB09245|Toloxatone MAOA;MAOA DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 1982:[DB09245 DB06735] DB09245|Toloxatone MAOA;MAOA DB06735|Enclomiphene CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 1983:[DB09245 DB06697] DB09245|Toloxatone MAOA;MAOA DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2B6;MAOA;CYP3A5;CYP2D6;CYP2C19 1984:[DB09245 DB04682] DB09245|Toloxatone MAOA;MAOA DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 1985:[DB09245 DB06997] DB09245|Toloxatone MAOA;MAOA DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways 1986:[DB09245 DB05464] DB09245|Toloxatone MAOA;MAOA DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways 1987:[DB09245 DB04381] DB09245|Toloxatone MAOA;MAOA DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;MAOA 1988:[DB09245 DB01095] DB09245|Toloxatone MAOA;MAOA DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP2B6;CYP3A4;CYP2C9;CYP1A1;HMGCR;MAOA 1989:[DB09245 DB01644] DB09245|Toloxatone MAOA;MAOA DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways GO:0055114| oxidation-reduction process MAOA;GSR 1990:[DB09245 DB03991] DB09245|Toloxatone MAOA;MAOA DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways 1991:[DB09245 DB08350] DB09245|Toloxatone MAOA;MAOA DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways 1992:[DB09245 DB08743] DB09245|Toloxatone MAOA;MAOA DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways 1993:[DB09245 DB05200] DB09245|Toloxatone MAOA;MAOA DB05200|AT2220 GAA common genes common pathways 1994:[DB09245 DB14707] DB09245|Toloxatone MAOA;MAOA DB14707|Cemiplimab PDCD1 common genes common pathways 1995:[DB09245 DB12960] DB09245|Toloxatone MAOA;MAOA DB12960|INCB-9471 CCR5 common genes common pathways 1996:[DB09245 DB14063] DB09245|Toloxatone MAOA;MAOA DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 1997:[DB09245 DB09333] DB09245|Toloxatone MAOA;MAOA DB09333|Iopodic acid DIO3;ALB common genes common pathways GO:0055114| oxidation-reduction process DIO3;MAOA 1998:[DB09245 DB09143] DB09245|Toloxatone MAOA;MAOA DB09143|Sonidegib SMO;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 1999:[DB09245 DB00293] DB09245|Toloxatone MAOA;MAOA DB00293|Raltitrexed TYMS;FPGS common genes common pathways 2000:[DB09245 DB07602] DB09245|Toloxatone MAOA;MAOA DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways 2001:[DB09245 DB07609] DB09245|Toloxatone MAOA;MAOA DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;MAOA 2002:[DB09245 DB04617] DB09245|Toloxatone MAOA;MAOA DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2003:[DB09245 DB00576] DB09245|Toloxatone MAOA;MAOA DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA 2004:[DB09245 DB08238] DB09245|Toloxatone MAOA;MAOA DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways 2005:[DB09245 DB00151] DB09245|Toloxatone MAOA;MAOA DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CBS;CDO1 2006:[DB09245 DB02751] DB09245|Toloxatone MAOA;MAOA DB02751|Glycocyamine GAMT common genes common pathways 2007:[DB09245 DB03185] DB09245|Toloxatone MAOA;MAOA DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 2008:[DB09245 DB03453] DB09245|Toloxatone MAOA;MAOA DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways 2009:[DB09245 DB08024] DB09245|Toloxatone MAOA;MAOA DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways 2010:[DB09245 DB00074] DB09245|Toloxatone MAOA;MAOA DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways 2011:[DB09245 DB03516] DB09245|Toloxatone MAOA;MAOA DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0055114| oxidation-reduction process DPYD;AOX1;XDH;MAOA 2012:[DB09245 DB03128] DB09245|Toloxatone MAOA;MAOA DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2013:[DB09245 DB14570] DB09245|Toloxatone MAOA;MAOA DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2014:[DB09245 DB05773] DB09245|Toloxatone MAOA;MAOA DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP3A5 2015:[DB09245 DB02198] DB09245|Toloxatone MAOA;MAOA DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1 2016:[DB09245 DB00148] DB09245|Toloxatone MAOA;MAOA DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways 2017:[DB09245 DB07780] DB09245|Toloxatone MAOA;MAOA DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways 2018:[DB09245 DB06090] DB09245|Toloxatone MAOA;MAOA DB06090|Bradanicline CHRNA7 common genes common pathways 2019:[DB09245 DB13151] DB09245|Toloxatone MAOA;MAOA DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0055114| oxidation-reduction process F8;MAOA 2020:[DB09245 DB11914] DB09245|Toloxatone MAOA;MAOA DB11914|Lebrikizumab IL13;IL13 common genes common pathways 2021:[DB09245 DB09099] DB09245|Toloxatone MAOA;MAOA DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2022:[DB09245 DB06843] DB09245|Toloxatone MAOA;MAOA DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways 2023:[DB09245 DB08675] DB09245|Toloxatone MAOA;MAOA DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways GO:0055114| oxidation-reduction process PTGIS;MAOA 2024:[DB09245 DB00039] DB09245|Toloxatone MAOA;MAOA DB00039|Palifermin FGFR2;NRP1;FGFR1;FGFR4;FGFR3;HSPG2 common genes common pathways 2025:[DB09245 DB06699] DB09245|Toloxatone MAOA;MAOA DB06699|Degarelix GNRHR common genes common pathways 2026:[DB09245 DB04972] DB09245|Toloxatone MAOA;MAOA DB04972|Canfosfamide GSTP1 common genes common pathways 2027:[DB09245 DB14517] DB09245|Toloxatone MAOA;MAOA DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways 2028:[DB09245 DB11921] DB09245|Toloxatone MAOA;MAOA DB11921|Deflazacort CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2029:[DB09245 DB00762] DB09245|Toloxatone MAOA;MAOA DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP2B6;CYP3A7;MAOA 2030:[DB09245 DB00357] DB09245|Toloxatone MAOA;MAOA DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;MAOA;CYP11A1;CYP3A4;CYP19A1 2031:[DB09245 DB00243] DB09245|Toloxatone MAOA;MAOA DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;MAOA 2032:[DB09245 DB13144] DB09245|Toloxatone MAOA;MAOA DB13144|Lenograstim CSF3R common genes common pathways 2033:[DB09245 DB06191] DB09245|Toloxatone MAOA;MAOA DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways 2034:[DB09245 DB08104] DB09245|Toloxatone MAOA;MAOA DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways 2035:[DB09245 DB00884] DB09245|Toloxatone MAOA;MAOA DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 2036:[DB09245 DB04334] DB09245|Toloxatone MAOA;MAOA DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;AOC3 2037:[DB09245 DB14041] DB09245|Toloxatone MAOA;MAOA DB14041|Fremanezumab CALCA;CALCB common genes common pathways 2038:[DB09245 DB05265] DB09245|Toloxatone MAOA;MAOA DB05265|Ecabet NOXO1;ureC common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOXO1 2039:[DB09245 DB09309] DB09245|Toloxatone MAOA;MAOA DB09309|Kitasamycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2040:[DB09245 DB01056] DB09245|Toloxatone MAOA;MAOA DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2041:[DB09245 DB08057] DB09245|Toloxatone MAOA;MAOA DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways 2042:[DB09245 DB00976] DB09245|Toloxatone MAOA;MAOA DB00976|Telithromycin CYP3A7;CYP3A4;CYP3A5;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP3A5 2043:[DB09245 DB11487] DB09245|Toloxatone MAOA;MAOA DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2044:[DB09245 DB11093] DB09245|Toloxatone MAOA;MAOA DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways 2045:[DB09245 DB08358] DB09245|Toloxatone MAOA;MAOA DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 2046:[DB09245 DB11948] DB09245|Toloxatone MAOA;MAOA DB11948|Lapachone RBP3 common genes common pathways 2047:[DB09245 DB04327] DB09245|Toloxatone MAOA;MAOA DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways 2048:[DB09245 DB08688] DB09245|Toloxatone MAOA;MAOA DB08688|undecan-2-one ACOT13 common genes common pathways 2049:[DB09245 DB06880] DB09245|Toloxatone MAOA;MAOA DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways 2050:[DB09245 DB08693] DB09245|Toloxatone MAOA;MAOA DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 2051:[DB09245 DB00127] DB09245|Toloxatone MAOA;MAOA DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process XDH;MAOA;SMOX 2052:[DB09245 DB06420] DB09245|Toloxatone MAOA;MAOA DB06420|Annamycin TOP2A common genes common pathways 2053:[DB09245 DB07382] DB09245|Toloxatone MAOA;MAOA DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways 2054:[DB09245 DB01712] DB09245|Toloxatone MAOA;MAOA DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways 2055:[DB09245 DB00301] DB09245|Toloxatone MAOA;MAOA DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2056:[DB09245 DB00547] DB09245|Toloxatone MAOA;MAOA DB00547|Desoximetasone NR3C1 common genes common pathways 2057:[DB09245 DB04835] DB09245|Toloxatone MAOA;MAOA DB04835|Maraviroc CCR5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2058:[DB09245 DB00868] DB09245|Toloxatone MAOA;MAOA DB00868|Benzonatate SCN5A common genes common pathways 2059:[DB09245 DB07795] DB09245|Toloxatone MAOA;MAOA DB07795|Fisetin CDK6 common genes common pathways 2060:[DB09245 DB00255] DB09245|Toloxatone MAOA;MAOA DB00255|Diethylstilbestrol ESR1;ESRRG;ESR2;ESRRA;ESRRB;NCOA2;NR1I2;AR;SHBG;COMT;CYP19A1;CYP3A4;CYP2C8;CYP2C9;CYP2E1;TTR;ABCG2;ABCB1;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP2C9;CYP2E1;CYP3A4;CYP19A1 GO:0042420| dopamine catabolic process MAOA;COMT GO:0006584| catecholamine metabolic process MAOA;COMT GO:0042135| neurotransmitter catabolic process MAOA;COMT 2061:[DB09245 DB07201] DB09245|Toloxatone MAOA;MAOA DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways 2062:[DB09245 DB05446] DB09245|Toloxatone MAOA;MAOA DB05446|LJP 1082 APOH common genes common pathways 2063:[DB09245 DB04573] DB09245|Toloxatone MAOA;MAOA DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways 2064:[DB09245 DB06963] DB09245|Toloxatone MAOA;MAOA DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways 2065:[DB09245 DB00893] DB09245|Toloxatone MAOA;MAOA DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0055114| oxidation-reduction process FTH1;MAOA 2066:[DB09245 DB00128] DB09245|Toloxatone MAOA;MAOA DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process MAOA;ASPH 2067:[DB09245 DB06321] DB09245|Toloxatone MAOA;MAOA DB06321|R-348 JAK3 common genes common pathways 2068:[DB09245 DB02281] DB09245|Toloxatone MAOA;MAOA DB02281|Formycin MTAP common genes common pathways 2069:[DB09245 DB13874] DB09245|Toloxatone MAOA;MAOA DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;IDH2;CYP2B6;CYP3A4;CYP2C9;CYP2D6;CYP2C8;CYP2C19 2070:[DB09245 DB02598] DB09245|Toloxatone MAOA;MAOA DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0055114| oxidation-reduction process PAM;MAOA 2071:[DB09245 DB05209] DB09245|Toloxatone MAOA;MAOA DB05209|SYM001 RHD common genes common pathways 2072:[DB09245 DB14639] DB09245|Toloxatone MAOA;MAOA DB14639|Boldenone undecylenate AR common genes common pathways 2073:[DB09245 DB06802] DB09245|Toloxatone MAOA;MAOA DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;PTGS2;MAOA 2074:[DB09245 DB01764] DB09245|Toloxatone MAOA;MAOA DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2075:[DB09245 DB00345] DB09245|Toloxatone MAOA;MAOA DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways 2076:[DB09245 DB02783] DB09245|Toloxatone MAOA;MAOA DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 2077:[DB09245 DB06444] DB09245|Toloxatone MAOA;MAOA DB06444|Dexanabinol TNF common genes common pathways 2078:[DB09245 DB05595] DB09245|Toloxatone MAOA;MAOA DB05595|Farletuzumab FOLR1 common genes common pathways 2079:[DB09245 DB00061] DB09245|Toloxatone MAOA;MAOA DB00061|Pegademase bovine GRB2 common genes common pathways 2080:[DB09245 DB07002] DB09245|Toloxatone MAOA;MAOA DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 2081:[DB09245 DB07364] DB09245|Toloxatone MAOA;MAOA DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways 2082:[DB09245 DB14072] DB09245|Toloxatone MAOA;MAOA DB14072|Reversin 121 ABCB1 common genes common pathways 2083:[DB09245 DB05758] DB09245|Toloxatone MAOA;MAOA DB05758|CYT007-TNFQb TNF common genes common pathways 2084:[DB09245 DB07081] DB09245|Toloxatone MAOA;MAOA DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways 2085:[DB09245 DB00717] DB09245|Toloxatone MAOA;MAOA DB00717|Norethisterone PGR;CYP3A4;CYP3A5;CYP3A7;CYP2C19;ALB;SHBG;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;MAOA;CYP3A7;CYP3A4 2086:[DB09245 DB06495] DB09245|Toloxatone MAOA;MAOA DB06495|Onercept TNF common genes common pathways 2087:[DB09245 DB01897] DB09245|Toloxatone MAOA;MAOA DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways 2088:[DB09245 DB11471] DB09245|Toloxatone MAOA;MAOA DB11471|Tilmicosin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2089:[DB09245 DB08067] DB09245|Toloxatone MAOA;MAOA DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways 2090:[DB09245 DB02342] DB09245|Toloxatone MAOA;MAOA DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;COMT GO:0006584| catecholamine metabolic process MAOA;COMT GO:0042420| dopamine catabolic process MAOA;COMT GO:0055114| oxidation-reduction process CYP1B1;MAOA;CYP1A1;CYP19A1 2091:[DB09245 DB14502] DB09245|Toloxatone MAOA;MAOA DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways 2092:[DB09245 DB02417] DB09245|Toloxatone MAOA;MAOA DB02417|2,4,6-Tribromophenol TTR common genes common pathways 2093:[DB09245 DB09036] DB09245|Toloxatone MAOA;MAOA DB09036|Siltuximab IL6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2094:[DB09245 DB03542] DB09245|Toloxatone MAOA;MAOA DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 2095:[DB09245 DB11979] DB09245|Toloxatone MAOA;MAOA DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP3A5;CYP2C8;CYP2D6;MAOA;CYP3A7;CYP3A4 2096:[DB09245 DB06510] DB09245|Toloxatone MAOA;MAOA DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA;CYP2C8 2097:[DB09245 DB07776] DB09245|Toloxatone MAOA;MAOA DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1B1 2098:[DB09245 DB06689] DB09245|Toloxatone MAOA;MAOA DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MAOA 2099:[DB09245 DB09328] DB09245|Toloxatone MAOA;MAOA DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2E1;FADS1 2100:[DB09245 DB03597] DB09245|Toloxatone MAOA;MAOA DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways 2101:[DB09245 DB04857] DB09245|Toloxatone MAOA;MAOA DB04857|Brasofensine DRD2 common genes common pathways 2102:[DB09245 DB02661] DB09245|Toloxatone MAOA;MAOA DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways 2103:[DB09245 DB01026] DB09245|Toloxatone MAOA;MAOA DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;CYP51A1;CYP21A2;CYP26A1;MAOA;CYP1A2;CYP11B1;CYP19A1;CYP3A4;CYP4F12;CYP2C9;CYP1A1;CYP2A6;CYP2B6;CYP11A1;CYP1B1;CYP4F2;CYP3A5;CYP2D6;CYP2C8;CYP2C19 2104:[DB09245 DB08229] DB09245|Toloxatone MAOA;MAOA DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways 2105:[DB09245 DB02079] DB09245|Toloxatone MAOA;MAOA DB02079|Aminooxyacetic acid AGXT common genes common pathways 2106:[DB09245 DB05524] DB09245|Toloxatone MAOA;MAOA DB05524|Pelitinib EGFR common genes common pathways 2107:[DB09245 DB11155] DB09245|Toloxatone MAOA;MAOA DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A1;CYP1B1 2108:[DB09245 DB11644] DB09245|Toloxatone MAOA;MAOA DB11644|Tafamidis TTR common genes common pathways 2109:[DB09245 DB11751] DB09245|Toloxatone MAOA;MAOA DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways 2110:[DB09245 DB08373] DB09245|Toloxatone MAOA;MAOA DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways 2111:[DB09245 DB04911] DB09245|Toloxatone MAOA;MAOA DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;MAOA;CYP3A4;CYP2C9 2112:[DB09245 DB06475] DB09245|Toloxatone MAOA;MAOA DB06475|Ruplizumab CD40LG common genes common pathways 2113:[DB09245 DB01097] DB09245|Toloxatone MAOA;MAOA DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2C9;DHODH 2114:[DB09245 DB00670] DB09245|Toloxatone MAOA;MAOA DB00670|Pirenzepine CHRM1 common genes common pathways 2115:[DB09245 DB00113] DB09245|Toloxatone MAOA;MAOA DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways 2116:[DB09245 DB09237] DB09245|Toloxatone MAOA;MAOA DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP3A4;NOS2;MAOA 2117:[DB09245 DB04214] DB09245|Toloxatone MAOA;MAOA DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 2118:[DB09245 DB05382] DB09245|Toloxatone MAOA;MAOA DB05382|Iodine MT-ND5 common genes common pathways GO:0055114| oxidation-reduction process MT-ND5;MAOA 2119:[DB09245 DB02490] DB09245|Toloxatone MAOA;MAOA DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 2120:[DB09245 DB02106] DB09245|Toloxatone MAOA;MAOA DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways 2121:[DB09245 DB00570] DB09245|Toloxatone MAOA;MAOA DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6 2122:[DB09245 DB04348] DB09245|Toloxatone MAOA;MAOA DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0055114| oxidation-reduction process MAOA;ABCC4 2123:[DB09245 DB08035] DB09245|Toloxatone MAOA;MAOA DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways 2124:[DB09245 DB03338] DB09245|Toloxatone MAOA;MAOA DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways 2125:[DB09245 DB07354] DB09245|Toloxatone MAOA;MAOA DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways 2126:[DB09245 DB14538] DB09245|Toloxatone MAOA;MAOA DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;CYP11B1;CYP11B2;CYP3A4;HSD11B2;CYP3A5;HSD3B1;CYP2C8 2127:[DB09245 DB04661] DB09245|Toloxatone MAOA;MAOA DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways 2128:[DB09245 DB02343] DB09245|Toloxatone MAOA;MAOA DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 2129:[DB09245 DB08819] DB09245|Toloxatone MAOA;MAOA DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 2130:[DB09245 DB01384] DB09245|Toloxatone MAOA;MAOA DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2131:[DB09245 DB00627] DB09245|Toloxatone MAOA;MAOA DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 2132:[DB09245 DB00050] DB09245|Toloxatone MAOA;MAOA DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways 2133:[DB09245 DB06732] DB09245|Toloxatone MAOA;MAOA DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP1B1 2134:[DB09245 DB05983] DB09245|Toloxatone MAOA;MAOA DB05983|Bardoxolone methyl NFKBIA common genes common pathways 2135:[DB09245 DB09336] DB09245|Toloxatone MAOA;MAOA DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways 2136:[DB09245 DB09532] DB09245|Toloxatone MAOA;MAOA DB09532|Secretin human SCTR common genes common pathways 2137:[DB09245 DB04100] DB09245|Toloxatone MAOA;MAOA DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways 2138:[DB09245 DB03041] DB09245|Toloxatone MAOA;MAOA DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 2139:[DB09245 DB00126] DB09245|Toloxatone MAOA;MAOA DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0042420| dopamine catabolic process DBH;MAOA GO:0055114| oxidation-reduction process P4HA1;P3H1;OGFOD1;EGLN2;ALKBH2;EGLN3;DBH;PLOD3;EGLN1;BBOX1;PLOD1;PAM;MAOA;P3H2;KDM5D;TMLHE;PHYH;P4HTM;P3H3;PLOD2;ALKBH3;OGFOD2 2140:[DB09245 DB03442] DB09245|Toloxatone MAOA;MAOA DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways 2141:[DB09245 DB09413] DB09245|Toloxatone MAOA;MAOA DB09413|Monopotassium phosphate ALPI common genes common pathways 2142:[DB09245 DB06360] DB09245|Toloxatone MAOA;MAOA DB06360|Lucatumumab CD40 common genes common pathways 2143:[DB09245 DB02745] DB09245|Toloxatone MAOA;MAOA DB02745|Uridine LSM6;SLC29A1 common genes common pathways 2144:[DB09245 DB05017] DB09245|Toloxatone MAOA;MAOA DB05017|YSIL6 TNF;IL6 common genes common pathways 2145:[DB09245 DB03506] DB09245|Toloxatone MAOA;MAOA DB03506|9-Deazaadenine APRT common genes common pathways 2146:[DB09245 DB03455] DB09245|Toloxatone MAOA;MAOA DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways 2147:[DB09245 DB12119] DB09245|Toloxatone MAOA;MAOA DB12119|Gevokizumab IL1B common genes common pathways 2148:[DB09245 DB07617] DB09245|Toloxatone MAOA;MAOA DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;MAOA 2149:[DB09245 DB06636] DB09245|Toloxatone MAOA;MAOA DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2150:[DB09245 DB02587] DB09245|Toloxatone MAOA;MAOA DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes common pathways 2151:[DB09245 DB08049] DB09245|Toloxatone MAOA;MAOA DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0042135| neurotransmitter catabolic process COMT;MAOA GO:0006584| catecholamine metabolic process COMT;MAOA GO:0042420| dopamine catabolic process COMT;MAOA 2152:[DB09245 DB11198] DB09245|Toloxatone MAOA;MAOA DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;MAOA 2153:[DB09245 DB03040] DB09245|Toloxatone MAOA;MAOA DB03040|Nitrilotriacetic Acid LTF common genes common pathways 2154:[DB09245 DB00545] DB09245|Toloxatone MAOA;MAOA DB00545|Pyridostigmine ACHE;BCHE;ALB;CYP3A4 common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA GO:0055114| oxidation-reduction process CYP3A4;MAOA 2155:[DB09245 DB06549] DB09245|Toloxatone MAOA;MAOA DB06549|Labradimil BDKRB2 common genes common pathways 2156:[DB09245 DB12474] DB09245|Toloxatone MAOA;MAOA DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;MAOA;CYP3A4;CYP2C9 2157:[DB09245 DB00910] DB09245|Toloxatone MAOA;MAOA DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;CYP3A4;MAOA 2158:[DB09245 DB02405] DB09245|Toloxatone MAOA;MAOA DB02405|12-Bromododecanoic Acid PAEP common genes common pathways 2159:[DB09245 DB02010] DB09245|Toloxatone MAOA;MAOA DB02010|Staurosporine LCK;PIM1;ITK;SYK;MAPKAPK2;GSK3B;CSK;CDK2;PIK3CG;PDPK1;PRKCQ;ZAP70;CHRM1;ABCB1 common genes common pathways 2160:[DB09245 DB09035] DB09245|Toloxatone MAOA;MAOA DB09035|Nivolumab PDCD1 common genes common pathways 2161:[DB09245 DB12159] DB09245|Toloxatone MAOA;MAOA DB12159|Dupilumab IL4R common genes common pathways 2162:[DB09245 DB08770] DB09245|Toloxatone MAOA;MAOA DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways 2163:[DB09245 DB02900] DB09245|Toloxatone MAOA;MAOA DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways 2164:[DB09245 DB01076] DB09245|Toloxatone MAOA;MAOA DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;CYP2C19;CYP2C8;CYP2D6;CYP3A5;HMGCR;MAOA;CYP3A7;CYP2B6;CYP2C9;CYP3A4 2165:[DB09245 DB09073] DB09245|Toloxatone MAOA;MAOA DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2166:[DB09245 DB00424] DB09245|Toloxatone MAOA;MAOA DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 2167:[DB09245 DB09535] DB09245|Toloxatone MAOA;MAOA DB09535|Octocrylene ESR1;ESR2 common genes common pathways 2168:[DB09245 DB04021] DB09245|Toloxatone MAOA;MAOA DB04021|MF268 ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 2169:[DB09245 DB06307] DB09245|Toloxatone MAOA;MAOA DB06307|Apoptone BCL2 common genes common pathways 2170:[DB09245 DB09105] DB09245|Toloxatone MAOA;MAOA DB09105|Asfotase Alfa S1PR1 common genes common pathways 2171:[DB09245 DB12130] DB09245|Toloxatone MAOA;MAOA DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;MAOA;CYP2C19;CYP2C8;CYP3A5 2172:[DB09245 DB09039] DB09245|Toloxatone MAOA;MAOA DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;MAOA 2173:[DB09245 DB06325] DB09245|Toloxatone MAOA;MAOA DB06325|Pegpleranib PDGFB common genes common pathways 2174:[DB09245 DB07286] DB09245|Toloxatone MAOA;MAOA DB07286|BMS-564929 AR common genes common pathways 2175:[DB09245 DB04620] DB09245|Toloxatone MAOA;MAOA DB04620|Cycloleucine GRIN1 common genes common pathways 2176:[DB09245 DB07344] DB09245|Toloxatone MAOA;MAOA DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways 2177:[DB09245 DB06688] DB09245|Toloxatone MAOA;MAOA DB06688|Sipuleucel-T ACPP common genes common pathways 2178:[DB09245 DB05192] DB09245|Toloxatone MAOA;MAOA DB05192|MB07811 THRB common genes common pathways 2179:[DB09245 DB04519] DB09245|Toloxatone MAOA;MAOA DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 2180:[DB09245 DB03664] DB09245|Toloxatone MAOA;MAOA DB03664|UP5 CMPK1 common genes common pathways 2181:[DB09245 DB08088] DB09245|Toloxatone MAOA;MAOA DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways 2182:[DB09245 DB06730] DB09245|Toloxatone MAOA;MAOA DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP3A5 2183:[DB09245 DB06650] DB09245|Toloxatone MAOA;MAOA DB06650|Ofatumumab MS4A1 common genes common pathways 2184:[DB09245 DB04409] DB09245|Toloxatone MAOA;MAOA DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways 2185:[DB09245 DB08560] DB09245|Toloxatone MAOA;MAOA DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways 2186:[DB09245 DB07917] DB09245|Toloxatone MAOA;MAOA DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways 2187:[DB09245 DB03384] DB09245|Toloxatone MAOA;MAOA DB03384|Fica CASP7 common genes common pathways 2188:[DB09245 DB00530] DB09245|Toloxatone MAOA;MAOA DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;CYP1A2;MAOA;CYP2C8;CYP2D6;CYP3A5;CYP1B1 2189:[DB09245 DB00931] DB09245|Toloxatone MAOA;MAOA DB00931|Metacycline ALB common genes common pathways 2190:[DB09245 DB05233] DB09245|Toloxatone MAOA;MAOA DB05233|AP1081 ESR1 common genes common pathways 2191:[DB09245 DB07789] DB09245|Toloxatone MAOA;MAOA DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways 2192:[DB09245 DB01223] DB09245|Toloxatone MAOA;MAOA DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2E1;CYP3A4;CYP1A2;MAOA 2193:[DB09245 DB00108] DB09245|Toloxatone MAOA;MAOA DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways 2194:[DB09245 DB08930] DB09245|Toloxatone MAOA;MAOA DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP3A5;MAOA;CYP3A7;CYP3A4 2195:[DB09245 DB11858] DB09245|Toloxatone MAOA;MAOA DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways 2196:[DB09245 DB14132] DB09245|Toloxatone MAOA;MAOA DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2197:[DB09245 DB09070] DB09245|Toloxatone MAOA;MAOA DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0055114| oxidation-reduction process HSD3B1;MAOA;HSD3B2 GO:0006584| catecholamine metabolic process MAOA;SULT1A1 2198:[DB09245 DB02462] DB09245|Toloxatone MAOA;MAOA DB02462|Thiocoumarin NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 2199:[DB09245 DB00487] DB09245|Toloxatone MAOA;MAOA DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2200:[DB09245 DB07154] DB09245|Toloxatone MAOA;MAOA DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways 2201:[DB09245 DB13881] DB09245|Toloxatone MAOA;MAOA DB13881|Tisagenlecleucel CD19 common genes common pathways 2202:[DB09245 DB03703] DB09245|Toloxatone MAOA;MAOA DB03703|Cyclohexanol ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;MAOA 2203:[DB09245 DB13132] DB09245|Toloxatone MAOA;MAOA DB13132|Artemisinin CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;MAOA 2204:[DB09245 DB04852] DB09245|Toloxatone MAOA;MAOA DB04852|Implitapide MTTP common genes common pathways 2205:[DB09245 DB05920] DB09245|Toloxatone MAOA;MAOA DB05920|RTA 744 TOP2A common genes common pathways 2206:[DB09245 DB05938] DB09245|Toloxatone MAOA;MAOA DB05938|Edonerpic APP common genes common pathways 2207:[DB09245 DB11397] DB09245|Toloxatone MAOA;MAOA DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways 2208:[DB09245 DB00600] DB09245|Toloxatone MAOA;MAOA DB00600|Monobenzone TYR common genes common pathways GO:0055114| oxidation-reduction process TYR;MAOA 2209:[DB09245 DB03889] DB09245|Toloxatone MAOA;MAOA DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 2210:[DB09245 DB01831] DB09245|Toloxatone MAOA;MAOA DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways 2211:[DB09245 DB08435] DB09245|Toloxatone MAOA;MAOA DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways 2212:[DB09245 DB00104] DB09245|Toloxatone MAOA;MAOA DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MPO;MAOA;CYP3A4 2213:[DB09245 DB06410] DB09245|Toloxatone MAOA;MAOA DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP27A1 2214:[DB09245 DB06721] DB09245|Toloxatone MAOA;MAOA DB06721|Gimatecan SLCO1B1 common genes common pathways 2215:[DB09245 DB04853] DB09245|Toloxatone MAOA;MAOA DB04853|Binodenoson ADORA2A common genes common pathways 2216:[DB09245 DB06414] DB09245|Toloxatone MAOA;MAOA DB06414|Etravirine CYP3A4;CYP2C9;CYP2C19;ABCB1;ABCB4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;MAOA;CYP2C9;CYP3A4 2217:[DB09245 DB02515] DB09245|Toloxatone MAOA;MAOA DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways 2218:[DB09245 DB03486] DB09245|Toloxatone MAOA;MAOA DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways 2219:[DB09245 DB02107] DB09245|Toloxatone MAOA;MAOA DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 2220:[DB09245 DB04256] DB09245|Toloxatone MAOA;MAOA DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways 2221:[DB09245 DB06538] DB09245|Toloxatone MAOA;MAOA DB06538|Robalzotan HTR1A common genes common pathways 2222:[DB09245 DB08156] DB09245|Toloxatone MAOA;MAOA DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways 2223:[DB09245 DB08190] DB09245|Toloxatone MAOA;MAOA DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways GO:0055114| oxidation-reduction process NQO2;MAOA 2224:[DB09245 DB08221] DB09245|Toloxatone MAOA;MAOA DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways 2225:[DB09245 DB09280] DB09245|Toloxatone MAOA;MAOA DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;MAOA;CYP2B6;CYP3A4;CYP2C9 2226:[DB09245 DB04578] DB09245|Toloxatone MAOA;MAOA DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways 2227:[DB09245 DB11774] DB09245|Toloxatone MAOA;MAOA DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2228:[DB09245 DB04910] DB09245|Toloxatone MAOA;MAOA DB04910|Oxibendazole TUBB4B common genes common pathways 2229:[DB09245 DB08772] DB09245|Toloxatone MAOA;MAOA DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B10;MAOA;AKR1B1 2230:[DB09245 DB00471] DB09245|Toloxatone MAOA;MAOA DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2A6;CYP2C9;CYP3A4;PTGS1;ALOX5;CYP2C8 2231:[DB09245 DB08222] DB09245|Toloxatone MAOA;MAOA DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways 2232:[DB09245 DB13500] DB09245|Toloxatone MAOA;MAOA DB13500|Otilonium CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2233:[DB09245 DB01951] DB09245|Toloxatone MAOA;MAOA DB01951|Gpi-1046 FKBP1A common genes common pathways 2234:[DB09245 DB00140] DB09245|Toloxatone MAOA;MAOA DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes MAOA common pathways GO:0042133| neurotransmitter metabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOA GO:0042420| dopamine catabolic process MAOA GO:0006584| catecholamine metabolic process MAOA GO:0055114| oxidation-reduction process BLVRB;MAOA;MTHFR GO:0006576| cellular biogenic amine metabolic process MAOA 2235:[DB09245 DB01231] DB09245|Toloxatone MAOA;MAOA DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways 2236:[DB09245 DB00710] DB09245|Toloxatone MAOA;MAOA DB00710|Ibandronate FDPS common genes common pathways 2237:[DB09245 DB00144] DB09245|Toloxatone MAOA;MAOA DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways 2238:[DB09245 DB00511] DB09245|Toloxatone MAOA;MAOA DB00511|Acetyldigitoxin ATP1A1 common genes common pathways 2239:[DB09245 DB00917] DB09245|Toloxatone MAOA;MAOA DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP11A1;CYP19A1;ABCC4 2240:[DB09245 DB01583] DB09245|Toloxatone MAOA;MAOA DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8 2241:[DB09245 DB03292] DB09245|Toloxatone MAOA;MAOA DB03292|3-Phosphono-D-alanine PSPH common genes common pathways 2242:[DB09245 DB07700] DB09245|Toloxatone MAOA;MAOA DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;AKR1C3 2243:[DB09245 DB04951] DB09245|Toloxatone MAOA;MAOA DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2244:[DB09245 DB09230] DB09245|Toloxatone MAOA;MAOA DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2245:[DB09245 DB01264] DB09245|Toloxatone MAOA;MAOA DB01264|Darunavir pol;CYP3A4;SLCO1B1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2246:[DB09245 DB04957] DB09245|Toloxatone MAOA;MAOA DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP1A1;CYP3A4;MAOA 2247:[DB09245 DB04919] DB09245|Toloxatone MAOA;MAOA DB04919|Alfimeprase FGA;FGB common genes common pathways 2248:[DB09245 DB05679] DB09245|Toloxatone MAOA;MAOA DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways 2249:[DB09245 DB13203] DB09245|Toloxatone MAOA;MAOA DB13203|Bamifylline CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2250:[DB09245 DB06479] DB09245|Toloxatone MAOA;MAOA DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2251:[DB09245 DB08885] DB09245|Toloxatone MAOA;MAOA DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways 2252:[DB09245 DB03832] DB09245|Toloxatone MAOA;MAOA DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways 2253:[DB09245 DB11760] DB09245|Toloxatone MAOA;MAOA DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes common pathways 2254:[DB09245 DB08750] DB09245|Toloxatone MAOA;MAOA DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 2255:[DB09245 DB01456] DB09245|Toloxatone MAOA;MAOA DB01456|5-androstenedione CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2256:[DB09245 DB02691] DB09245|Toloxatone MAOA;MAOA DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways 2257:[DB09245 DB05514] DB09245|Toloxatone MAOA;MAOA DB05514|Cobiprostone CLCN2 common genes common pathways 2258:[DB09245 DB07831] DB09245|Toloxatone MAOA;MAOA DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways 2259:[DB09245 DB04794] DB09245|Toloxatone MAOA;MAOA DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1;CYP19A1;CYP3A4;CYP2B6 2260:[DB09245 DB12141] DB09245|Toloxatone MAOA;MAOA DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2261:[DB09245 DB00769] DB09245|Toloxatone MAOA;MAOA DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2262:[DB09245 DB07396] DB09245|Toloxatone MAOA;MAOA DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways 2263:[DB09245 DB05796] DB09245|Toloxatone MAOA;MAOA DB05796|Daglutril MME common genes common pathways 2264:[DB09245 DB00078] DB09245|Toloxatone MAOA;MAOA DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 2265:[DB09245 DB09140] DB09245|Toloxatone MAOA;MAOA DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0055114| oxidation-reduction process MAOA;MT-CO1;NOX1 2266:[DB09245 DB11614] DB09245|Toloxatone MAOA;MAOA DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9;CYP3A4;CYP2C19;CYP2D6 2267:[DB09245 DB08259] DB09245|Toloxatone MAOA;MAOA DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways 2268:[DB09245 DB01738] DB09245|Toloxatone MAOA;MAOA DB01738|Phosphorylcolamine PRKCB common genes common pathways 2269:[DB09245 DB14064] DB09245|Toloxatone MAOA;MAOA DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2270:[DB09245 DB07919] DB09245|Toloxatone MAOA;MAOA DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes MAOA common pathways GO:0042135| neurotransmitter catabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0006584| catecholamine metabolic process MAOA GO:0042420| dopamine catabolic process MAOA GO:0055114| oxidation-reduction process MAOA GO:0006576| cellular biogenic amine metabolic process MAOA 2271:[DB09245 DB03945] DB09245|Toloxatone MAOA;MAOA DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways 2272:[DB09245 DB09064] DB09245|Toloxatone MAOA;MAOA DB09064|Ciprofibrate PPARA common genes common pathways 2273:[DB09245 DB06145] DB09245|Toloxatone MAOA;MAOA DB06145|Spiramycin rplC;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2274:[DB09245 DB03451] DB09245|Toloxatone MAOA;MAOA DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways 2275:[DB09245 DB12118] DB09245|Toloxatone MAOA;MAOA DB12118|Sotatercept ACVR2A common genes common pathways 2276:[DB09245 DB02039] DB09245|Toloxatone MAOA;MAOA DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways 2277:[DB09245 DB05234] DB09245|Toloxatone MAOA;MAOA DB05234|LGD2941 AR common genes common pathways 2278:[DB09245 DB04757] DB09245|Toloxatone MAOA;MAOA DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways 2279:[DB09245 DB03435] DB09245|Toloxatone MAOA;MAOA DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways 2280:[DB09245 DB00773] DB09245|Toloxatone MAOA;MAOA DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;PTGS1;CYP3A4;CYP2E1;PTGS2;MAOA;CYP1A2 2281:[DB09245 DB08159] DB09245|Toloxatone MAOA;MAOA DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways 2282:[DB09245 DB08101] DB09245|Toloxatone MAOA;MAOA DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways 2283:[DB09245 DB12688] DB09245|Toloxatone MAOA;MAOA DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways 2284:[DB09245 DB02282] DB09245|Toloxatone MAOA;MAOA DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 2285:[DB09245 DB11869] DB09245|Toloxatone MAOA;MAOA DB11869|Valspodar SLCO1B1;SLCO1B3 common genes common pathways 2286:[DB09245 DB06039] DB09245|Toloxatone MAOA;MAOA DB06039|PA-1050040 gag common genes common pathways 2287:[DB09245 DB02311] DB09245|Toloxatone MAOA;MAOA DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways 2288:[DB09245 DB04069] DB09245|Toloxatone MAOA;MAOA DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways 2289:[DB09245 DB00592] DB09245|Toloxatone MAOA;MAOA DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 2290:[DB09245 DB01160] DB09245|Toloxatone MAOA;MAOA DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways 2291:[DB09245 DB13996] DB09245|Toloxatone MAOA;MAOA DB13996|Magnesium acetate ATP1A1 common genes common pathways 2292:[DB09245 DB00815] DB09245|Toloxatone MAOA;MAOA DB00815|Sodium lauryl sulfate ALB common genes common pathways 2293:[DB09245 DB03253] DB09245|Toloxatone MAOA;MAOA DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways 2294:[DB09245 DB12418] DB09245|Toloxatone MAOA;MAOA DB12418|Saccharin CA3 common genes common pathways 2295:[DB09245 DB07837] DB09245|Toloxatone MAOA;MAOA DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways 2296:[DB09245 DB01811] DB09245|Toloxatone MAOA;MAOA DB01811|3h-Indole-5,6-Diol LTF common genes common pathways 2297:[DB09245 DB00449] DB09245|Toloxatone MAOA;MAOA DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2298:[DB09245 DB12061] DB09245|Toloxatone MAOA;MAOA DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways 2299:[DB09245 DB06215] DB09245|Toloxatone MAOA;MAOA DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0055114| oxidation-reduction process FTH1;MAOA 2300:[DB09245 DB01444] DB09245|Toloxatone MAOA;MAOA DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes common pathways 2301:[DB09245 DB00446] DB09245|Toloxatone MAOA;MAOA DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP3A5;CYP2C19;CYP2C8 2302:[DB09245 DB05417] DB09245|Toloxatone MAOA;MAOA DB05417|GW 468816 GLRA1 common genes common pathways 2303:[DB09245 DB02338] DB09245|Toloxatone MAOA;MAOA DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0055114| oxidation-reduction process MAOA;AASS;TXNRD1;DPYD 2304:[DB09245 DB01973] DB09245|Toloxatone MAOA;MAOA DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 2305:[DB09245 DB09462] DB09245|Toloxatone MAOA;MAOA DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process ADH1B;MAOA;CYP2E1;ALDH1A1 2306:[DB09245 DB02508] DB09245|Toloxatone MAOA;MAOA DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways 2307:[DB09245 DB09340] DB09245|Toloxatone MAOA;MAOA DB09340|Tyropanoic acid GUSB common genes common pathways 2308:[DB09245 DB00825] DB09245|Toloxatone MAOA;MAOA DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2309:[DB09245 DB00207] DB09245|Toloxatone MAOA;MAOA DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2A6 2310:[DB09245 DB01128] DB09245|Toloxatone MAOA;MAOA DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2C9;CYP3A4;MAOA 2311:[DB09245 DB06290] DB09245|Toloxatone MAOA;MAOA DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA;CYP3A4 2312:[DB09245 DB07696] DB09245|Toloxatone MAOA;MAOA DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways 2313:[DB09245 DB06287] DB09245|Toloxatone MAOA;MAOA DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP3A4;MAOA;CYP3A7 2314:[DB09245 DB11995] DB09245|Toloxatone MAOA;MAOA DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA;CYP2C8 2315:[DB09245 DB06457] DB09245|Toloxatone MAOA;MAOA DB06457|Tecastemizole KCNH2 common genes common pathways 2316:[DB09245 DB05413] DB09245|Toloxatone MAOA;MAOA DB05413|Tifuvirtide SERPINA5 common genes common pathways 2317:[DB09245 DB07117] DB09245|Toloxatone MAOA;MAOA DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 2318:[DB09245 DB06371] DB09245|Toloxatone MAOA;MAOA DB06371|Siplizumab CD2 common genes common pathways 2319:[DB09245 DB06602] DB09245|Toloxatone MAOA;MAOA DB06602|Reslizumab IL5 common genes common pathways 2320:[DB09245 DB04119] DB09245|Toloxatone MAOA;MAOA DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways 2321:[DB09245 DB07930] DB09245|Toloxatone MAOA;MAOA DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;ACOX1 2322:[DB09245 DB11949] DB09245|Toloxatone MAOA;MAOA DB11949|Vestipitant TACR1 common genes common pathways 2323:[DB09245 DB07500] DB09245|Toloxatone MAOA;MAOA DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways 2324:[DB09245 DB01704] DB09245|Toloxatone MAOA;MAOA DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways 2325:[DB09245 DB12874] DB09245|Toloxatone MAOA;MAOA DB12874|Quizartinib FLT3 common genes common pathways 2326:[DB09245 DB05750] DB09245|Toloxatone MAOA;MAOA DB05750|AVE-1625 CNR1 common genes common pathways 2327:[DB09245 DB05394] DB09245|Toloxatone MAOA;MAOA DB05394|Corticorelin DBH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DBH GO:0042420| dopamine catabolic process DBH;MAOA 2328:[DB09245 DB04115] DB09245|Toloxatone MAOA;MAOA DB04115|Berberine BIRC5 common genes common pathways 2329:[DB09245 DB02660] DB09245|Toloxatone MAOA;MAOA DB02660|Filaminast PDE4B common genes common pathways 2330:[DB09245 DB00720] DB09245|Toloxatone MAOA;MAOA DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 2331:[DB09245 DB01147] DB09245|Toloxatone MAOA;MAOA DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 2332:[DB09245 DB02932] DB09245|Toloxatone MAOA;MAOA DB02932|(R)-Bicalutamide AR common genes common pathways 2333:[DB09245 DB00120] DB09245|Toloxatone MAOA;MAOA DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process TH;PAH;MAOA 2334:[DB09245 DB07677] DB09245|Toloxatone MAOA;MAOA DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 2335:[DB09245 DB02758] DB09245|Toloxatone MAOA;MAOA DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways 2336:[DB09245 DB07509] DB09245|Toloxatone MAOA;MAOA DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways 2337:[DB09245 DB00224] DB09245|Toloxatone MAOA;MAOA DB00224|Indinavir pol;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;ABCB1;SLC22A1;ABCC1;SLCO1A2;SLCO1B1;ABCC2;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;CYP3A4;CYP2D6;CYP3A5 2338:[DB09245 DB01647] DB09245|Toloxatone MAOA;MAOA DB01647|Daxalipram PDE4B common genes common pathways 2339:[DB09245 DB00869] DB09245|Toloxatone MAOA;MAOA DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C9 2340:[DB09245 DB03849] DB09245|Toloxatone MAOA;MAOA DB03849|Cilomilast PDE4D;PDE4B common genes common pathways 2341:[DB09245 DB06674] DB09245|Toloxatone MAOA;MAOA DB06674|Golimumab TNF common genes common pathways 2342:[DB09245 DB07701] DB09245|Toloxatone MAOA;MAOA DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 2343:[DB09245 DB11636] DB09245|Toloxatone MAOA;MAOA DB11636|Nomegestrol CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2344:[DB09245 DB07561] DB09245|Toloxatone MAOA;MAOA DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 2345:[DB09245 DB00147] DB09245|Toloxatone MAOA;MAOA DB00147|Pyridoxal PDXK common genes common pathways 2346:[DB09245 DB01541] DB09245|Toloxatone MAOA;MAOA DB01541|Boldenone AR common genes common pathways 2347:[DB09245 DB00133] DB09245|Toloxatone MAOA;MAOA DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CBS 2348:[DB09245 DB13749] DB09245|Toloxatone MAOA;MAOA DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways 2349:[DB09245 DB12089] DB09245|Toloxatone MAOA;MAOA DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2350:[DB09245 DB07173] DB09245|Toloxatone MAOA;MAOA DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 2351:[DB09245 DB00539] DB09245|Toloxatone MAOA;MAOA DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;MAOA 2352:[DB09245 DB02890] DB09245|Toloxatone MAOA;MAOA DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways 2353:[DB09245 DB00066] DB09245|Toloxatone MAOA;MAOA DB00066|Follitropin FSHR common genes common pathways 2354:[DB09245 DB01873] DB09245|Toloxatone MAOA;MAOA DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2355:[DB09245 DB11595] DB09245|Toloxatone MAOA;MAOA DB11595|Atezolizumab CD274 common genes common pathways 2356:[DB09245 DB01751] DB09245|Toloxatone MAOA;MAOA DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways 2357:[DB09245 DB02774] DB09245|Toloxatone MAOA;MAOA DB02774|1,3-Propandiol ARF1 common genes common pathways 2358:[DB09245 DB04856] DB09245|Toloxatone MAOA;MAOA DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;MAOA;CYP3A5 2359:[DB09245 DB01582] DB09245|Toloxatone MAOA;MAOA DB01582|Sulfamethazine ALB common genes common pathways 2360:[DB09245 DB03944] DB09245|Toloxatone MAOA;MAOA DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 2361:[DB09245 DB04466] DB09245|Toloxatone MAOA;MAOA DB04466|SR12813 NR1I2 common genes common pathways 2362:[DB09245 DB02115] DB09245|Toloxatone MAOA;MAOA DB02115|Daidzin ALDH2;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;MAOA 2363:[DB09245 DB09310] DB09245|Toloxatone MAOA;MAOA DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 2364:[DB09245 DB05012] DB09245|Toloxatone MAOA;MAOA DB05012|XEN2174 SLC6A2 common genes common pathways 2365:[DB09245 DB02636] DB09245|Toloxatone MAOA;MAOA DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways 2366:[DB09245 DB04436] DB09245|Toloxatone MAOA;MAOA DB04436|3-Fluorotyrosine SOD2 common genes common pathways GO:0055114| oxidation-reduction process SOD2;MAOA 2367:[DB09245 DB09047] DB09245|Toloxatone MAOA;MAOA DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways 2368:[DB09245 DB00643] DB09245|Toloxatone MAOA;MAOA DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP1A1 2369:[DB09245 DB01666] DB09245|Toloxatone MAOA;MAOA DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways 2370:[DB09245 DB04121] DB09245|Toloxatone MAOA;MAOA DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways 2371:[DB09245 DB06249] DB09245|Toloxatone MAOA;MAOA DB06249|Arzoxifene ESR1;ESR2 common genes common pathways 2372:[DB09245 DB04941] DB09245|Toloxatone MAOA;MAOA DB04941|Crofelemer CFTR;ANO1 common genes common pathways 2373:[DB09245 DB06133] DB09245|Toloxatone MAOA;MAOA DB06133|Dimethylcurcumin AR common genes common pathways 2374:[DB09245 DB07193] DB09245|Toloxatone MAOA;MAOA DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways 2375:[DB09245 DB07754] DB09245|Toloxatone MAOA;MAOA DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways 2376:[DB09245 DB12379] DB09245|Toloxatone MAOA;MAOA DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A1 2377:[DB09245 DB13999] DB09245|Toloxatone MAOA;MAOA DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0055114| oxidation-reduction process MAOA;PHYH 2378:[DB09245 DB06205] DB09245|Toloxatone MAOA;MAOA DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes common pathways 2379:[DB09245 DB11450] DB09245|Toloxatone MAOA;MAOA DB11450|Pimobendan CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2380:[DB09245 DB01838] DB09245|Toloxatone MAOA;MAOA DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways 2381:[DB09245 DB08020] DB09245|Toloxatone MAOA;MAOA DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways 2382:[DB09245 DB02236] DB09245|Toloxatone MAOA;MAOA DB02236|Glycinamide Ribonucleotide GART common genes common pathways 2383:[DB09245 DB01185] DB09245|Toloxatone MAOA;MAOA DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0055114| oxidation-reduction process MAOA;HSD11B2 2384:[DB09245 DB01756] DB09245|Toloxatone MAOA;MAOA DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 2385:[DB09245 DB08971] DB09245|Toloxatone MAOA;MAOA DB08971|Fluocortolone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2386:[DB09245 DB06926] DB09245|Toloxatone MAOA;MAOA DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways 2387:[DB09245 DB06691] DB09245|Toloxatone MAOA;MAOA DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 2388:[DB09245 DB13488] DB09245|Toloxatone MAOA;MAOA DB13488|Bencyclane CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2389:[DB09245 DB07318] DB09245|Toloxatone MAOA;MAOA DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 2390:[DB09245 DB08087] DB09245|Toloxatone MAOA;MAOA DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways 2391:[DB09245 DB00146] DB09245|Toloxatone MAOA;MAOA DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP27B1;MAOA;CYP24A1 2392:[DB09245 DB00741] DB09245|Toloxatone MAOA;MAOA DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A7;CYP11B2;CYP11B1;CYP3A4;HSD3B1;CYP3A5;HSD11B2;CYP2C8 2393:[DB09245 DB06210] DB09245|Toloxatone MAOA;MAOA DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP1A2 2394:[DB09245 DB06421] DB09245|Toloxatone MAOA;MAOA DB06421|Declopramide TOP2A;TOP2B common genes common pathways 2395:[DB09245 DB13133] DB09245|Toloxatone MAOA;MAOA DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0055114| oxidation-reduction process MAOA;F8 2396:[DB09245 DB07977] DB09245|Toloxatone MAOA;MAOA DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 2397:[DB09245 DB00233] DB09245|Toloxatone MAOA;MAOA DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;ALOX5;MPO 2398:[DB09245 DB03183] DB09245|Toloxatone MAOA;MAOA DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 2399:[DB09245 DB11606] DB09245|Toloxatone MAOA;MAOA DB11606|Susoctocog alfa VWF common genes common pathways 2400:[DB09245 DB05155] DB09245|Toloxatone MAOA;MAOA DB05155|CR665 OPRK1 common genes common pathways 2401:[DB09245 DB00585] DB09245|Toloxatone MAOA;MAOA DB00585|Nizatidine HRH2;BCHE;ABCB1 common genes common pathways 2402:[DB09245 DB01357] DB09245|Toloxatone MAOA;MAOA DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9;CYP3A4;CYP2C8 2403:[DB09245 DB02553] DB09245|Toloxatone MAOA;MAOA DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways GO:0055114| oxidation-reduction process MAOA;GSR 2404:[DB09245 DB04572] DB09245|Toloxatone MAOA;MAOA DB04572|Thiotepa CYP2B6;CYP3A4;BCHE common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;MAOA 2405:[DB09245 DB00613] DB09245|Toloxatone MAOA;MAOA DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C8;MAOA;CYP2C9;CYP1A1 2406:[DB09245 DB09266] DB09245|Toloxatone MAOA;MAOA DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways 2407:[DB09245 DB02011] DB09245|Toloxatone MAOA;MAOA DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways 2408:[DB09245 DB04709] DB09245|Toloxatone MAOA;MAOA DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways 2409:[DB09245 DB01777] DB09245|Toloxatone MAOA;MAOA DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways 2410:[DB09245 DB14518] DB09245|Toloxatone MAOA;MAOA DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways 2411:[DB09245 DB07684] DB09245|Toloxatone MAOA;MAOA DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways 2412:[DB09245 DB00220] DB09245|Toloxatone MAOA;MAOA DB00220|Nelfinavir CYP2B6;CYP2C19;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;CYP2C9;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2B6;MAOA;CYP3A7;CYP3A5;CYP2C19;CYP2D6 2413:[DB09245 DB07300] DB09245|Toloxatone MAOA;MAOA DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways 2414:[DB09245 DB12733] DB09245|Toloxatone MAOA;MAOA DB12733|Dipraglurant GRM5 common genes common pathways 2415:[DB09245 DB02735] DB09245|Toloxatone MAOA;MAOA DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways 2416:[DB09245 DB00169] DB09245|Toloxatone MAOA;MAOA DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP2R1;MAOA;CYP2B6;CYP11A1;CYP2J2;CYP1A1;CYP27A1;CYP3A4 2417:[DB09245 DB02507] DB09245|Toloxatone MAOA;MAOA DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA 2418:[DB09245 DB06150] DB09245|Toloxatone MAOA;MAOA DB06150|Sulfadimethoxine CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA 2419:[DB09245 DB03169] DB09245|Toloxatone MAOA;MAOA DB03169|(S)-Hmg-Coa HMGCR common genes common pathways GO:0055114| oxidation-reduction process MAOA;HMGCR 2420:[DB09245 DB01586] DB09245|Toloxatone MAOA;MAOA DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1;ABCC4;AKR1C2 2421:[DB09245 DB05495] DB09245|Toloxatone MAOA;MAOA DB05495|PG-530742 MMP9 common genes common pathways 2422:[DB09245 DB11113] DB09245|Toloxatone MAOA;MAOA DB11113|Castor oil PTGER3;PTGER4 common genes common pathways 2423:[DB09245 DB11633] DB09245|Toloxatone MAOA;MAOA DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2C9;CYP2B6;MAOA 2424:[DB09245 DB12339] DB09245|Toloxatone MAOA;MAOA DB12339|Radezolid RRBP1;NIP7 common genes common pathways 2425:[DB09245 DB11085] DB09245|Toloxatone MAOA;MAOA DB11085|Resorcinol TPO common genes common pathways GO:0055114| oxidation-reduction process MAOA;TPO 2426:[DB09245 DB13772] DB09245|Toloxatone MAOA;MAOA DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2427:[DB09245 DB12267] DB09245|Toloxatone MAOA;MAOA DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP2C8;CYP3A5;CYP3A43 2428:[DB09245 DB03866] DB09245|Toloxatone MAOA;MAOA DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 2429:[DB09245 DB03085] DB09245|Toloxatone MAOA;MAOA DB03085|Glycolic acid G6PD;thiO common genes common pathways GO:0055114| oxidation-reduction process G6PD;MAOA 2430:[DB09245 DB12579] DB09245|Toloxatone MAOA;MAOA DB12579|JNJ-37822681 DRD2 common genes common pathways 2431:[DB09245 DB03773] DB09245|Toloxatone MAOA;MAOA DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways 2432:[DB09245 DB09074] DB09245|Toloxatone MAOA;MAOA DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2B6 2433:[DB09245 DB07460] DB09245|Toloxatone MAOA;MAOA DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways 2434:[DB09245 DB05116] DB09245|Toloxatone MAOA;MAOA DB05116|Thymectacin TYMS common genes common pathways 2435:[DB09245 DB00411] DB09245|Toloxatone MAOA;MAOA DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 2436:[DB09245 DB00957] DB09245|Toloxatone MAOA;MAOA DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2437:[DB09245 DB04860] DB09245|Toloxatone MAOA;MAOA DB04860|Isatoribine TLR7 common genes common pathways 2438:[DB09245 DB00291] DB09245|Toloxatone MAOA;MAOA DB00291|Chlorambucil GSTP1;SLCO1A2 common genes common pathways 2439:[DB09245 DB08228] DB09245|Toloxatone MAOA;MAOA DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways GO:0055114| oxidation-reduction process NQO2;MAOA 2440:[DB09245 DB05046] DB09245|Toloxatone MAOA;MAOA DB05046|V1003 OPRK1;OPRM1 common genes common pathways 2441:[DB09245 DB06901] DB09245|Toloxatone MAOA;MAOA DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 2442:[DB09245 DB07691] DB09245|Toloxatone MAOA;MAOA DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways 2443:[DB09245 DB01214] DB09245|Toloxatone MAOA;MAOA DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 2444:[DB09245 DB00044] DB09245|Toloxatone MAOA;MAOA DB00044|Lutropin alfa LHCGR common genes common pathways 2445:[DB09245 DB07693] DB09245|Toloxatone MAOA;MAOA DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways 2446:[DB09245 DB06064] DB09245|Toloxatone MAOA;MAOA DB06064|KAI-1455 PRKCE common genes common pathways 2447:[DB09245 DB07517] DB09245|Toloxatone MAOA;MAOA DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways 2448:[DB09245 DB08157] DB09245|Toloxatone MAOA;MAOA DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways 2449:[DB09245 DB00040] DB09245|Toloxatone MAOA;MAOA DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 2450:[DB09245 DB00309] DB09245|Toloxatone MAOA;MAOA DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2451:[DB09245 DB11087] DB09245|Toloxatone MAOA;MAOA DB11087|Pyrethrum extract NR1I2 common genes common pathways 2452:[DB09245 DB11988] DB09245|Toloxatone MAOA;MAOA DB11988|Ocrelizumab MS4A1 common genes common pathways 2453:[DB09245 DB05455] DB09245|Toloxatone MAOA;MAOA DB05455|SR 121463 AVPR1B common genes common pathways 2454:[DB09245 DB14034] DB09245|Toloxatone MAOA;MAOA DB14034|Darglitazone PPARG common genes common pathways 2455:[DB09245 DB09102] DB09245|Toloxatone MAOA;MAOA DB09102|Daclatasvir CYP3A5;CYP3A4;CYP3A43;CYP3A7;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A7;CYP3A4;CYP3A43;CYP3A5 2456:[DB09245 DB07559] DB09245|Toloxatone MAOA;MAOA DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 2457:[DB09245 DB00640] DB09245|Toloxatone MAOA;MAOA DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways 2458:[DB09245 DB08692] DB09245|Toloxatone MAOA;MAOA DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 2459:[DB09245 DB04881] DB09245|Toloxatone MAOA;MAOA DB04881|Elacridar ABCB1;ABCG2;SLCO1B1 common genes common pathways 2460:[DB09245 DB03962] DB09245|Toloxatone MAOA;MAOA DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways GO:0055114| oxidation-reduction process MAOA;PGD 2461:[DB09245 DB08736] DB09245|Toloxatone MAOA;MAOA DB08736|S,R-Warfarin alcohol ALB common genes common pathways 2462:[DB09245 DB06533] DB09245|Toloxatone MAOA;MAOA DB06533|Ragaglitazar PPARA;PPARG common genes common pathways 2463:[DB09245 DB06472] DB09245|Toloxatone MAOA;MAOA DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways 2464:[DB09245 DB07247] DB09245|Toloxatone MAOA;MAOA DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways 2465:[DB09245 DB07140] DB09245|Toloxatone MAOA;MAOA DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 2466:[DB09245 DB05916] DB09245|Toloxatone MAOA;MAOA DB05916|CT-011 PDCD1 common genes common pathways 2467:[DB09245 DB07814] DB09245|Toloxatone MAOA;MAOA DB07814|Gibberellic acid AADACL2 common genes common pathways 2468:[DB09245 DB01902] DB09245|Toloxatone MAOA;MAOA DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways GO:0055114| oxidation-reduction process MAOA;ERO1B 2469:[DB09245 DB02568] DB09245|Toloxatone MAOA;MAOA DB02568|Peldesine PNP common genes common pathways 2470:[DB09245 DB06750] DB09245|Toloxatone MAOA;MAOA DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways 2471:[DB09245 DB03609] DB09245|Toloxatone MAOA;MAOA DB03609|3-Deoxyguanosine PNP common genes common pathways 2472:[DB09245 DB13949] DB09245|Toloxatone MAOA;MAOA DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways 2473:[DB09245 DB01092] DB09245|Toloxatone MAOA;MAOA DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;MAOA 2474:[DB09245 DB01077] DB09245|Toloxatone MAOA;MAOA DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 2475:[DB09245 DB03255] DB09245|Toloxatone MAOA;MAOA DB03255|Phenol cobT;ALB common genes common pathways 2476:[DB09245 DB05125] DB09245|Toloxatone MAOA;MAOA DB05125|SC12267 DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 2477:[DB09245 DB05487] DB09245|Toloxatone MAOA;MAOA DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways 2478:[DB09245 DB00942] DB09245|Toloxatone MAOA;MAOA DB00942|Cycrimine CHRM1 common genes common pathways 2479:[DB09245 DB08860] DB09245|Toloxatone MAOA;MAOA DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;HMGCR;MAOA;CYP2C8 2480:[DB09245 DB12010] DB09245|Toloxatone MAOA;MAOA DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;ALOX5 2481:[DB09245 DB08077] DB09245|Toloxatone MAOA;MAOA DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways 2482:[DB09245 DB14533] DB09245|Toloxatone MAOA;MAOA DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0055114| oxidation-reduction process PDIA3;MAOA;P4HB;GAPDHS;SOD1;PRDX1;CCS;CP;ADH1C 2483:[DB09245 DB07962] DB09245|Toloxatone MAOA;MAOA DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways 2484:[DB09245 DB03861] DB09245|Toloxatone MAOA;MAOA DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways 2485:[DB09245 DB07714] DB09245|Toloxatone MAOA;MAOA DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways GO:0055114| oxidation-reduction process MAOA;GSR 2486:[DB09245 DB01966] DB09245|Toloxatone MAOA;MAOA DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways 2487:[DB09245 DB04816] DB09245|Toloxatone MAOA;MAOA DB04816|Dantron ALB common genes common pathways 2488:[DB09245 DB01698] DB09245|Toloxatone MAOA;MAOA DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CBR1;CYP3A4;AKR1C3;MAOA 2489:[DB09245 DB03994] DB09245|Toloxatone MAOA;MAOA DB03994|Ethanolamine ANXA3 common genes common pathways 2490:[DB09245 DB04400] DB09245|Toloxatone MAOA;MAOA DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0055114| oxidation-reduction process MAOA;PAH;NOS2;TH;PCBD1 2491:[DB09245 DB01791] DB09245|Toloxatone MAOA;MAOA DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways 2492:[DB09245 DB00896] DB09245|Toloxatone MAOA;MAOA DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2493:[DB09245 DB04594] DB09245|Toloxatone MAOA;MAOA DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways 2494:[DB09245 DB06789] DB09245|Toloxatone MAOA;MAOA DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;MAOA;CYP3A4 2495:[DB09245 DB03645] DB09245|Toloxatone MAOA;MAOA DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways 2496:[DB09245 DB02581] DB09245|Toloxatone MAOA;MAOA DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways 2497:[DB09245 DB00485] DB09245|Toloxatone MAOA;MAOA DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2498:[DB09245 DB06599] DB09245|Toloxatone MAOA;MAOA DB06599|Lexatumumab TNFRSF10B common genes common pathways 2499:[DB09245 DB12070] DB09245|Toloxatone MAOA;MAOA DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP3A43;CYP2B6;CYP3A4;CYP2C9;CYP3A7;MAOA 2500:[DB09245 DB05471] DB09245|Toloxatone MAOA;MAOA DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways 2501:[DB09245 DB06870] DB09245|Toloxatone MAOA;MAOA DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways 2502:[DB09245 DB07395] DB09245|Toloxatone MAOA;MAOA DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways 2503:[DB09245 DB08119] DB09245|Toloxatone MAOA;MAOA DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 2504:[DB09245 DB07072] DB09245|Toloxatone MAOA;MAOA DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways 2505:[DB09245 DB01640] DB09245|Toloxatone MAOA;MAOA DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways 2506:[DB09245 DB00520] DB09245|Toloxatone MAOA;MAOA DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2507:[DB09245 DB05708] DB09245|Toloxatone MAOA;MAOA DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2E1 2508:[DB09245 DB08843] DB09245|Toloxatone MAOA;MAOA DB08843|GS 0573 SLC22A6 common genes common pathways 2509:[DB09245 DB00383] DB09245|Toloxatone MAOA;MAOA DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways 2510:[DB09245 DB07613] DB09245|Toloxatone MAOA;MAOA DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways 2511:[DB09245 DB00180] DB09245|Toloxatone MAOA;MAOA DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2512:[DB09245 DB06147] DB09245|Toloxatone MAOA;MAOA DB06147|Sulfathiazole CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;MAOA 2513:[DB09245 DB01662] DB09245|Toloxatone MAOA;MAOA DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways 2514:[DB09245 DB07849] DB09245|Toloxatone MAOA;MAOA DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways 2515:[DB09245 DB11855] DB09245|Toloxatone MAOA;MAOA DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 2516:[DB09245 DB00641] DB09245|Toloxatone MAOA;MAOA DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;HMGCR;CYP3A4;CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C8;CYP2C19 2517:[DB09245 DB12515] DB09245|Toloxatone MAOA;MAOA DB12515|9-aminocamptothecin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2518:[DB09245 DB07007] DB09245|Toloxatone MAOA;MAOA DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 2519:[DB09245 DB05253] DB09245|Toloxatone MAOA;MAOA DB05253|Proellex PGR common genes common pathways 2520:[DB09245 DB04418] DB09245|Toloxatone MAOA;MAOA DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways 2521:[DB09245 DB00523] DB09245|Toloxatone MAOA;MAOA DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP26C1 2522:[DB09245 DB00259] DB09245|Toloxatone MAOA;MAOA DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2E1;CYP3A4;MAOA 2523:[DB09245 DB00288] DB09245|Toloxatone MAOA;MAOA DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2524:[DB09245 DB00279] DB09245|Toloxatone MAOA;MAOA DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2525:[DB09245 DB00156] DB09245|Toloxatone MAOA;MAOA DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways 2526:[DB09245 DB04975] DB09245|Toloxatone MAOA;MAOA DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;CYP1A1;MAOA 2527:[DB09245 DB13503] DB09245|Toloxatone MAOA;MAOA DB13503|Tyrothricin ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2528:[DB09245 DB03124] DB09245|Toloxatone MAOA;MAOA DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways 2529:[DB09245 DB00636] DB09245|Toloxatone MAOA;MAOA DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP2E1;CYP3A4;CYP2B6;CYP2A6;MAOA;CYP4A11 2530:[DB09245 DB08626] DB09245|Toloxatone MAOA;MAOA DB08626|Thiorphan MME common genes common pathways 2531:[DB09245 DB06042] DB09245|Toloxatone MAOA;MAOA DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways 2532:[DB09245 DB14724] DB09245|Toloxatone MAOA;MAOA DB14724|Emapalumab IFNG common genes common pathways 2533:[DB09245 DB03425] DB09245|Toloxatone MAOA;MAOA DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways 2534:[DB09245 DB08060] DB09245|Toloxatone MAOA;MAOA DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways 2535:[DB09245 DB01742] DB09245|Toloxatone MAOA;MAOA DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways 2536:[DB09245 DB00750] DB09245|Toloxatone MAOA;MAOA DB00750|Prilocaine SCN5A common genes common pathways 2537:[DB09245 DB05849] DB09245|Toloxatone MAOA;MAOA DB05849|NCX 950 ADRB2 common genes common pathways 2538:[DB09245 DB03470] DB09245|Toloxatone MAOA;MAOA DB03470|Trypanothione TPR common genes common pathways 2539:[DB09245 DB04445] DB09245|Toloxatone MAOA;MAOA DB04445|Mercuric iodide SULT2A1 common genes common pathways 2540:[DB09245 DB04133] DB09245|Toloxatone MAOA;MAOA DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 2541:[DB09245 DB12923] DB09245|Toloxatone MAOA;MAOA DB12923|Gallopamil CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2542:[DB09245 DB04934] DB09245|Toloxatone MAOA;MAOA DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2543:[DB09245 DB00751] DB09245|Toloxatone MAOA;MAOA DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2B6;CYP3A4;MAOA 2544:[DB09245 DB00621] DB09245|Toloxatone MAOA;MAOA DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9 2545:[DB09245 DB08972] DB09245|Toloxatone MAOA;MAOA DB08972|Flumequine CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2546:[DB09245 DB05824] DB09245|Toloxatone MAOA;MAOA DB05824|CNS-5161 GRIN1 common genes common pathways 2547:[DB09245 DB03988] DB09245|Toloxatone MAOA;MAOA DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways 2548:[DB09245 DB11793] DB09245|Toloxatone MAOA;MAOA DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways 2549:[DB09245 DB03316] DB09245|Toloxatone MAOA;MAOA DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways 2550:[DB09245 DB06185] DB09245|Toloxatone MAOA;MAOA DB06185|Forodesine PNP common genes common pathways 2551:[DB09245 DB00199] DB09245|Toloxatone MAOA;MAOA DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;CYP3A7;MAOA;CYP1A2;CYP3A5 2552:[DB09245 DB08445] DB09245|Toloxatone MAOA;MAOA DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways 2553:[DB09245 DB05875] DB09245|Toloxatone MAOA;MAOA DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;CYP19A1 2554:[DB09245 DB04880] DB09245|Toloxatone MAOA;MAOA DB04880|Enoximone PDE3A common genes common pathways 2555:[DB09245 DB08801] DB09245|Toloxatone MAOA;MAOA DB08801|Dimetindene HRH1;CHRM2 common genes common pathways 2556:[DB09245 DB00947] DB09245|Toloxatone MAOA;MAOA DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2557:[DB09245 DB06932] DB09245|Toloxatone MAOA;MAOA DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways 2558:[DB09245 DB01762] DB09245|Toloxatone MAOA;MAOA DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways 2559:[DB09245 DB02089] DB09245|Toloxatone MAOA;MAOA DB02089|CP-526423 PYGL common genes common pathways 2560:[DB09245 DB01134] DB09245|Toloxatone MAOA;MAOA DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2561:[DB09245 DB00527] DB09245|Toloxatone MAOA;MAOA DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways 2562:[DB09245 DB00253] DB09245|Toloxatone MAOA;MAOA DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2563:[DB09245 DB05386] DB09245|Toloxatone MAOA;MAOA DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways 2564:[DB09245 DB05429] DB09245|Toloxatone MAOA;MAOA DB05429|CAT-213 CCL11 common genes common pathways 2565:[DB09245 DB09051] DB09245|Toloxatone MAOA;MAOA DB09051|Elosulfase alfa GALNS common genes common pathways 2566:[DB09245 DB06781] DB09245|Toloxatone MAOA;MAOA DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2567:[DB09245 DB09151] DB09245|Toloxatone MAOA;MAOA DB09151|Flutemetamol (18F) APP common genes common pathways 2568:[DB09245 DB07815] DB09245|Toloxatone MAOA;MAOA DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways 2569:[DB09245 DB03478] DB09245|Toloxatone MAOA;MAOA DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways 2570:[DB09245 DB01481] DB09245|Toloxatone MAOA;MAOA DB01481|1-Testosterone AR common genes common pathways 2571:[DB09245 DB01892] DB09245|Toloxatone MAOA;MAOA DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS1;MAOA 2572:[DB09245 DB01141] DB09245|Toloxatone MAOA;MAOA DB01141|Micafungin COMT;ARSA common genes common pathways GO:0042420| dopamine catabolic process MAOA;COMT GO:0006584| catecholamine metabolic process COMT;MAOA GO:0042135| neurotransmitter catabolic process MAOA;COMT 2573:[DB09245 DB06804] DB09245|Toloxatone MAOA;MAOA DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 2574:[DB09245 DB00826] DB09245|Toloxatone MAOA;MAOA DB00826|Natamycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2575:[DB09245 DB02008] DB09245|Toloxatone MAOA;MAOA DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 2576:[DB09245 DB13346] DB09245|Toloxatone MAOA;MAOA DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;PTGS1 2577:[DB09245 DB11742] DB09245|Toloxatone MAOA;MAOA DB11742|Ebastine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2578:[DB09245 DB06742] DB09245|Toloxatone MAOA;MAOA DB06742|Ambroxol CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2579:[DB09245 DB03546] DB09245|Toloxatone MAOA;MAOA DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 2580:[DB09245 DB00287] DB09245|Toloxatone MAOA;MAOA DB00287|Travoprost PTGFR common genes common pathways 2581:[DB09245 DB01006] DB09245|Toloxatone MAOA;MAOA DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;CYP2A6;MAOA 2582:[DB09245 DB01378] DB09245|Toloxatone MAOA;MAOA DB01378|Magnesium cation ATP1A1 common genes common pathways 2583:[DB09245 DB13931] DB09245|Toloxatone MAOA;MAOA DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways 2584:[DB09245 DB04837] DB09245|Toloxatone MAOA;MAOA DB04837|Clofedanol HRH1 common genes common pathways 2585:[DB09245 DB05161] DB09245|Toloxatone MAOA;MAOA DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0055114| oxidation-reduction process MAOA;MPO 2586:[DB09245 DB00179] DB09245|Toloxatone MAOA;MAOA DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2J2;ALOX5 2587:[DB09245 DB07879] DB09245|Toloxatone MAOA;MAOA DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways 2588:[DB09245 DB07453] DB09245|Toloxatone MAOA;MAOA DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2589:[DB09245 DB00257] DB09245|Toloxatone MAOA;MAOA DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP19A1;CYP2C9;CYP2E1;CYP2A6;CYP11A1;CYP2B6;CYP3A7;MAOA;CYP11B1 2590:[DB09245 DB02179] DB09245|Toloxatone MAOA;MAOA DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways 2591:[DB09245 DB03747] DB09245|Toloxatone MAOA;MAOA DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways 2592:[DB09245 DB06819] DB09245|Toloxatone MAOA;MAOA DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 2593:[DB09245 DB07668] DB09245|Toloxatone MAOA;MAOA DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways 2594:[DB09245 DB07383] DB09245|Toloxatone MAOA;MAOA DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways 2595:[DB09245 DB08865] DB09245|Toloxatone MAOA;MAOA DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A7;CYP3A4;CYP2B6;CYP3A43;CYP3A5 2596:[DB09245 DB05304] DB09245|Toloxatone MAOA;MAOA DB05304|WX-G250 CA9;IL2 common genes common pathways 2597:[DB09245 DB00419] DB09245|Toloxatone MAOA;MAOA DB00419|Miglustat UGCG common genes common pathways 2598:[DB09245 DB00602] DB09245|Toloxatone MAOA;MAOA DB00602|Ivermectin GLRA3;GABRB3;CYP3A4;ABCB1;ABCC1;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2599:[DB09245 DB01763] DB09245|Toloxatone MAOA;MAOA DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways GO:0055114| oxidation-reduction process NNT;MAOA 2600:[DB09245 DB00155] DB09245|Toloxatone MAOA;MAOA DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS1;NOS2;NOS3 2601:[DB09245 DB01091] DB09245|Toloxatone MAOA;MAOA DB01091|Butenafine SQLE common genes common pathways GO:0055114| oxidation-reduction process MAOA;SQLE 2602:[DB09245 DB07003] DB09245|Toloxatone MAOA;MAOA DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 2603:[DB09245 DB00281] DB09245|Toloxatone MAOA;MAOA DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA;CYP3A7;CYP2C9;CYP3A4;CYP2B6;CYP2A6;CYP3A5;CYP2C18;CYP2C8;CYP2D6 2604:[DB09245 DB12340] DB09245|Toloxatone MAOA;MAOA DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways 2605:[DB09245 DB04606] DB09245|Toloxatone MAOA;MAOA DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways 2606:[DB09245 DB01110] DB09245|Toloxatone MAOA;MAOA DB01110|Miconazole NOS3;NOS2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;KCNH2;KCNH6;KCNH7;NR1I2;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP11B1;CYP51A1;CYP19A1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;NOS3;CYP2D6;CYP2B6;NOS2;CYP2A6;CYP2C9;CYP2E1;CYP3A4;CYP19A1;CYP11B1;MAOA;CYP51A1 2607:[DB09245 DB04890] DB09245|Toloxatone MAOA;MAOA DB04890|Bepotastine HRH1 common genes common pathways 2608:[DB09245 DB07992] DB09245|Toloxatone MAOA;MAOA DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways 2609:[DB09245 DB03101] DB09245|Toloxatone MAOA;MAOA DB03101|Ribose-1-Phosphate PNP common genes common pathways 2610:[DB09245 DB08055] DB09245|Toloxatone MAOA;MAOA DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways 2611:[DB09245 DB13981] DB09245|Toloxatone MAOA;MAOA DB13981|Nomegestrol acetate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2612:[DB09245 DB01776] DB09245|Toloxatone MAOA;MAOA DB01776|M-Cresol INS common genes common pathways 2613:[DB09245 DB09087] DB09245|Toloxatone MAOA;MAOA DB09087|Potassium alum ALB common genes common pathways 2614:[DB09245 DB07342] DB09245|Toloxatone MAOA;MAOA DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;HMOX1 2615:[DB09245 DB04377] DB09245|Toloxatone MAOA;MAOA DB04377|Meglutol HMGCR common genes common pathways GO:0055114| oxidation-reduction process MAOA;HMGCR 2616:[DB09245 DB08206] DB09245|Toloxatone MAOA;MAOA DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways 2617:[DB09245 DB03010] DB09245|Toloxatone MAOA;MAOA DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2618:[DB09245 DB02147] DB09245|Toloxatone MAOA;MAOA DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways 2619:[DB09245 DB04106] DB09245|Toloxatone MAOA;MAOA DB04106|Fotemustine TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process TXNRD1;MAOA 2620:[DB09245 DB00032] DB09245|Toloxatone MAOA;MAOA DB00032|Menotropins FSHR;LHCGR common genes common pathways 2621:[DB09245 DB11652] DB09245|Toloxatone MAOA;MAOA DB11652|Tucatinib ERBB2 common genes common pathways 2622:[DB09245 DB08615] DB09245|Toloxatone MAOA;MAOA DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2623:[DB09245 DB13158] DB09245|Toloxatone MAOA;MAOA DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2624:[DB09245 DB02097] DB09245|Toloxatone MAOA;MAOA DB02097|Cytidine UCK2 common genes common pathways 2625:[DB09245 DB14042] DB09245|Toloxatone MAOA;MAOA DB14042|Galcanezumab CALCA;CALCB common genes common pathways 2626:[DB09245 DB05416] DB09245|Toloxatone MAOA;MAOA DB05416|Cardarine PPARD;PPARA common genes common pathways 2627:[DB09245 DB13914] DB09245|Toloxatone MAOA;MAOA DB13914|Volixibat SLC10A2 common genes common pathways 2628:[DB09245 DB03317] DB09245|Toloxatone MAOA;MAOA DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYCS;CYP2C9 2629:[DB09245 DB04027] DB09245|Toloxatone MAOA;MAOA DB04027|D-Arginine CKM common genes common pathways 2630:[DB09245 DB06433] DB09245|Toloxatone MAOA;MAOA DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0055114| oxidation-reduction process MAOA;RRM1 2631:[DB09245 DB04516] DB09245|Toloxatone MAOA;MAOA DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways 2632:[DB09245 DB06727] DB09245|Toloxatone MAOA;MAOA DB06727|Sparteine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 2633:[DB09245 DB00406] DB09245|Toloxatone MAOA;MAOA DB00406|Gentian violet cation SLC22A1 common genes common pathways 2634:[DB09245 DB05309] DB09245|Toloxatone MAOA;MAOA DB05309|TP-508 FGF4 common genes common pathways 2635:[DB09245 DB03621] DB09245|Toloxatone MAOA;MAOA DB03621|L-709,587 FKBP1A common genes common pathways 2636:[DB09245 DB05050] DB09245|Toloxatone MAOA;MAOA DB05050|ADL5859 OPRD1 common genes common pathways 2637:[DB09245 DB07348] DB09245|Toloxatone MAOA;MAOA DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2638:[DB09245 DB00929] DB09245|Toloxatone MAOA;MAOA DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways 2639:[DB09245 DB01270] DB09245|Toloxatone MAOA;MAOA DB01270|Ranibizumab VEGFA common genes common pathways 2640:[DB09245 DB00799] DB09245|Toloxatone MAOA;MAOA DB00799|Tazarotene RARA;RXRB;RARG;RARB;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C8 2641:[DB09245 DB01581] DB09245|Toloxatone MAOA;MAOA DB01581|Sulfamerazine ALB common genes common pathways 2642:[DB09245 DB07246] DB09245|Toloxatone MAOA;MAOA DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 2643:[DB09245 DB09033] DB09245|Toloxatone MAOA;MAOA DB09033|Vedolizumab ITGA4;ITGB7 common genes common pathways 2644:[DB09245 DB01000] DB09245|Toloxatone MAOA;MAOA DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 2645:[DB09245 DB00847] DB09245|Toloxatone MAOA;MAOA DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;MAOA 2646:[DB09245 DB07029] DB09245|Toloxatone MAOA;MAOA DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 2647:[DB09245 DB06939] DB09245|Toloxatone MAOA;MAOA DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways 2648:[DB09245 DB06162] DB09245|Toloxatone MAOA;MAOA DB06162|Lumiliximab FCER2 common genes common pathways 2649:[DB09245 DB04270] DB09245|Toloxatone MAOA;MAOA DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways 2650:[DB09245 DB06097] DB09245|Toloxatone MAOA;MAOA DB06097|GSK-923295 CENPE common genes common pathways 2651:[DB09245 DB09234] DB09245|Toloxatone MAOA;MAOA DB09234|Darodipine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2652:[DB09245 DB09459] DB09245|Toloxatone MAOA;MAOA DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways GO:0055114| oxidation-reduction process MAOA;HIF1AN 2653:[DB09245 DB08916] DB09245|Toloxatone MAOA;MAOA DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways 2654:[DB09245 DB05787] DB09245|Toloxatone MAOA;MAOA DB05787|LM-609 ITGB3 common genes common pathways 2655:[DB09245 DB08884] DB09245|Toloxatone MAOA;MAOA DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;MAOA 2656:[DB09245 DB12712] DB09245|Toloxatone MAOA;MAOA DB12712|Pilsicainide ABCB11 common genes common pathways 2657:[DB09245 DB12961] DB09245|Toloxatone MAOA;MAOA DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways 2658:[DB09245 DB05458] DB09245|Toloxatone MAOA;MAOA DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways 2659:[DB09245 DB05109] DB09245|Toloxatone MAOA;MAOA DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2E1;CYP2C9;PTGS1;CYP2D6;CYP2C19 2660:[DB09245 DB06778] DB09245|Toloxatone MAOA;MAOA DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes MAOA common pathways GO:0042420| dopamine catabolic process MAOA;MAOB GO:0006584| catecholamine metabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOB;MAOA GO:0006576| cellular biogenic amine metabolic process MAOA GO:0055114| oxidation-reduction process CP;TYR;MT-CO1;MAOB;MAOA;LOX;PAH;SOD1 2661:[DB09245 DB01038] DB09245|Toloxatone MAOA;MAOA DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways 2662:[DB09245 DB09028] DB09245|Toloxatone MAOA;MAOA DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways 2663:[DB09245 DB08234] DB09245|Toloxatone MAOA;MAOA DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 2664:[DB09245 DB00744] DB09245|Toloxatone MAOA;MAOA DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0055114| oxidation-reduction process PTGS1;ALOX5;CYP3A4;CYP2C9;MAOA;CYP1A2 2665:[DB09245 DB05777] DB09245|Toloxatone MAOA;MAOA DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways 2666:[DB09245 DB03351] DB09245|Toloxatone MAOA;MAOA DB03351|Sri-9439 DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 2667:[DB09245 DB09067] DB09245|Toloxatone MAOA;MAOA DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways 2668:[DB09245 DB08605] DB09245|Toloxatone MAOA;MAOA DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways GO:0055114| oxidation-reduction process MAOA;DECR1 2669:[DB09245 DB05934] DB09245|Toloxatone MAOA;MAOA DB05934|CTCE-0214 CXCL12 common genes common pathways 2670:[DB09245 DB06408] DB09245|Toloxatone MAOA;MAOA DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0055114| oxidation-reduction process IMPDH1;MAOA 2671:[DB09245 DB03515] DB09245|Toloxatone MAOA;MAOA DB03515|Equilenin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2672:[DB09245 DB05260] DB09245|Toloxatone MAOA;MAOA DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0055114| oxidation-reduction process RRM2;MAOA 2673:[DB09245 DB04977] DB09245|Toloxatone MAOA;MAOA DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;CYP2E1;CYP3A4;MAOA;CYP4A11 2674:[DB09245 DB01520] DB09245|Toloxatone MAOA;MAOA DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways 2675:[DB09245 DB00724] DB09245|Toloxatone MAOA;MAOA DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2676:[DB09245 DB03467] DB09245|Toloxatone MAOA;MAOA DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1;AKR1C1;CYP1B1 2677:[DB09245 DB02230] DB09245|Toloxatone MAOA;MAOA DB02230|Immucillin-G PNP common genes common pathways 2678:[DB09245 DB00367] DB09245|Toloxatone MAOA;MAOA DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;MAOA;SRD5A1 2679:[DB09245 DB07756] DB09245|Toloxatone MAOA;MAOA DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2680:[DB09245 DB08612] DB09245|Toloxatone MAOA;MAOA DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 2681:[DB09245 DB07142] DB09245|Toloxatone MAOA;MAOA DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 2682:[DB09245 DB02888] DB09245|Toloxatone MAOA;MAOA DB02888|FKB-001 FKBP1A common genes common pathways 2683:[DB09245 DB03766] DB09245|Toloxatone MAOA;MAOA DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;GPHN 2684:[DB09245 DB03552] DB09245|Toloxatone MAOA;MAOA DB03552|3-Tyrosine TH common genes common pathways GO:0055114| oxidation-reduction process TH;MAOA 2685:[DB09245 DB02464] DB09245|Toloxatone MAOA;MAOA DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways 2686:[DB09245 DB08208] DB09245|Toloxatone MAOA;MAOA DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways 2687:[DB09245 DB02468] DB09245|Toloxatone MAOA;MAOA DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;MAOA 2688:[DB09245 DB00171] DB09245|Toloxatone MAOA;MAOA DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0055114| oxidation-reduction process MAOA;ABCC4 2689:[DB09245 DB05766] DB09245|Toloxatone MAOA;MAOA DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways 2690:[DB09245 DB00123] DB09245|Toloxatone MAOA;MAOA DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways 2691:[DB09245 DB00352] DB09245|Toloxatone MAOA;MAOA DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;ABCC4 2692:[DB09245 DB00445] DB09245|Toloxatone MAOA;MAOA DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways 2693:[DB09245 DB03909] DB09245|Toloxatone MAOA;MAOA DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways 2694:[DB09245 DB02152] DB09245|Toloxatone MAOA;MAOA DB02152|K-252a MET;MAP2K1 common genes common pathways 2695:[DB09245 DB04875] DB09245|Toloxatone MAOA;MAOA DB04875|Pralnacasan CASP1 common genes common pathways 2696:[DB09245 DB08205] DB09245|Toloxatone MAOA;MAOA DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways 2697:[DB09245 DB05223] DB09245|Toloxatone MAOA;MAOA DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways 2698:[DB09245 DB03788] DB09245|Toloxatone MAOA;MAOA DB03788|GC-24 THRB common genes common pathways 2699:[DB09245 DB02678] DB09245|Toloxatone MAOA;MAOA DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways 2700:[DB09245 DB12698] DB09245|Toloxatone MAOA;MAOA DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways 2701:[DB09245 DB01597] DB09245|Toloxatone MAOA;MAOA DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways 2702:[DB09245 DB04048] DB09245|Toloxatone MAOA;MAOA DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PRDX2 2703:[DB09245 DB01709] DB09245|Toloxatone MAOA;MAOA DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways 2704:[DB09245 DB00095] DB09245|Toloxatone MAOA;MAOA DB00095|Efalizumab ITGAL;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 2705:[DB09245 DB09526] DB09245|Toloxatone MAOA;MAOA DB09526|Hydroquinone TYR;ALB common genes common pathways GO:0055114| oxidation-reduction process MAOA;TYR 2706:[DB09245 DB07456] DB09245|Toloxatone MAOA;MAOA DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways 2707:[DB09245 DB02187] DB09245|Toloxatone MAOA;MAOA DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process HSD17B1;CYP3A4;MAOA 2708:[DB09245 DB00043] DB09245|Toloxatone MAOA;MAOA DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways 2709:[DB09245 DB01194] DB09245|Toloxatone MAOA;MAOA DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2710:[DB09245 DB09343] DB09245|Toloxatone MAOA;MAOA DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways 2711:[DB09245 DB00974] DB09245|Toloxatone MAOA;MAOA DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1 2712:[DB09245 DB00240] DB09245|Toloxatone MAOA;MAOA DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2713:[DB09245 DB05282] DB09245|Toloxatone MAOA;MAOA DB05282|MCC AIFM1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;AIFM1 2714:[DB09245 DB00954] DB09245|Toloxatone MAOA;MAOA DB00954|Dirithromycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2715:[DB09245 DB05249] DB09245|Toloxatone MAOA;MAOA DB05249|FavId CSF3R common genes common pathways 2716:[DB09245 DB08448] DB09245|Toloxatone MAOA;MAOA DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 2717:[DB09245 DB06600] DB09245|Toloxatone MAOA;MAOA DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2718:[DB09245 DB06497] DB09245|Toloxatone MAOA;MAOA DB06497|Aplaviroc CCR5 common genes common pathways 2719:[DB09245 DB00860] DB09245|Toloxatone MAOA;MAOA DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2720:[DB09245 DB07717] DB09245|Toloxatone MAOA;MAOA DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways 2721:[DB09245 DB06176] DB09245|Toloxatone MAOA;MAOA DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP1A1;CYP3A4;CYP2B6;MAOA 2722:[DB09245 DB00846] DB09245|Toloxatone MAOA;MAOA DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2723:[DB09245 DB01125] DB09245|Toloxatone MAOA;MAOA DB01125|Anisindione GGCX common genes common pathways 2724:[DB09245 DB01606] DB09245|Toloxatone MAOA;MAOA DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways 2725:[DB09245 DB00360] DB09245|Toloxatone MAOA;MAOA DB00360|Sapropterin PAH;NOS3;TH;TPH1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;PAH;TH;TPH1;NOS3 2726:[DB09245 DB06909] DB09245|Toloxatone MAOA;MAOA DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways 2727:[DB09245 DB00481] DB09245|Toloxatone MAOA;MAOA DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;AOX1;CYP2B6;MAOA;CYP2C8 2728:[DB09245 DB01536] DB09245|Toloxatone MAOA;MAOA DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process HSD3B1;HSD17B1;CYP3A4;AKR1C3;MAOA 2729:[DB09245 DB12095] DB09245|Toloxatone MAOA;MAOA DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;TPH2;TPH1 2730:[DB09245 DB08806] DB09245|Toloxatone MAOA;MAOA DB08806|Roxatidine acetate HRH2 common genes common pathways 2731:[DB09245 DB12498] DB09245|Toloxatone MAOA;MAOA DB12498|Mogamulizumab CXCR4 common genes common pathways 2732:[DB09245 DB00827] DB09245|Toloxatone MAOA;MAOA DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2733:[DB09245 DB11967] DB09245|Toloxatone MAOA;MAOA DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP1A2;MAOA 2734:[DB09245 DB01632] DB09245|Toloxatone MAOA;MAOA DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways 2735:[DB09245 DB02821] DB09245|Toloxatone MAOA;MAOA DB02821|Canaline OAT common genes common pathways 2736:[DB09245 DB05812] DB09245|Toloxatone MAOA;MAOA DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP2D6;CYP2C8;CYP2C19;MAOA;CYP1A2;CYP3A4;CYP2C9 2737:[DB09245 DB01370] DB09245|Toloxatone MAOA;MAOA DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways 2738:[DB09245 DB08800] DB09245|Toloxatone MAOA;MAOA DB08800|Chloropyramine HRH1 common genes common pathways 2739:[DB09245 DB07239] DB09245|Toloxatone MAOA;MAOA DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways 2740:[DB09245 DB08384] DB09245|Toloxatone MAOA;MAOA DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways 2741:[DB09245 DB05398] DB09245|Toloxatone MAOA;MAOA DB05398|C31G CD9 common genes common pathways 2742:[DB09245 DB02746] DB09245|Toloxatone MAOA;MAOA DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways 2743:[DB09245 DB00892] DB09245|Toloxatone MAOA;MAOA DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways 2744:[DB09245 DB02558] DB09245|Toloxatone MAOA;MAOA DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways 2745:[DB09245 DB08530] DB09245|Toloxatone MAOA;MAOA DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways 2746:[DB09245 DB13925] DB09245|Toloxatone MAOA;MAOA DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways 2747:[DB09245 DB00005] DB09245|Toloxatone MAOA;MAOA DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways 2748:[DB09245 DB02512] DB09245|Toloxatone MAOA;MAOA DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways 2749:[DB09245 DB12589] DB09245|Toloxatone MAOA;MAOA DB12589|Dacetuzumab CD40 common genes common pathways 2750:[DB09245 DB01012] DB09245|Toloxatone MAOA;MAOA DB01012|Cinacalcet CASR;CYP3A4;CYP2D6;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP3A4;CYP2D6 2751:[DB09245 DB07106] DB09245|Toloxatone MAOA;MAOA DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways 2752:[DB09245 DB09097] DB09245|Toloxatone MAOA;MAOA DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways 2753:[DB09245 DB04886] DB09245|Toloxatone MAOA;MAOA DB04886|Calanolide A CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2754:[DB09245 DB05075] DB09245|Toloxatone MAOA;MAOA DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways 2755:[DB09245 DB04736] DB09245|Toloxatone MAOA;MAOA DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways 2756:[DB09245 DB05364] DB09245|Toloxatone MAOA;MAOA DB05364|ROX-888 CCL3 common genes common pathways 2757:[DB09245 DB00067] DB09245|Toloxatone MAOA;MAOA DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways 2758:[DB09245 DB05204] DB09245|Toloxatone MAOA;MAOA DB05204|XL418 BTK common genes common pathways 2759:[DB09245 DB02902] DB09245|Toloxatone MAOA;MAOA DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways 2760:[DB09245 DB07646] DB09245|Toloxatone MAOA;MAOA DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 2761:[DB09245 DB01667] DB09245|Toloxatone MAOA;MAOA DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2762:[DB09245 DB05016] DB09245|Toloxatone MAOA;MAOA DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways 2763:[DB09245 DB01341] DB09245|Toloxatone MAOA;MAOA DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways 2764:[DB09245 DB02183] DB09245|Toloxatone MAOA;MAOA DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways 2765:[DB09245 DB00129] DB09245|Toloxatone MAOA;MAOA DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways 2766:[DB09245 DB08868] DB09245|Toloxatone MAOA;MAOA DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0055114| oxidation-reduction process CYP4F12;CYP2E1;MAOA;CYP4F2 2767:[DB09245 DB09274] DB09245|Toloxatone MAOA;MAOA DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2A6 2768:[DB09245 DB11919] DB09245|Toloxatone MAOA;MAOA DB11919|6-O-benzylguanine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2769:[DB09245 DB06928] DB09245|Toloxatone MAOA;MAOA DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways 2770:[DB09245 DB11575] DB09245|Toloxatone MAOA;MAOA DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2771:[DB09245 DB08881] DB09245|Toloxatone MAOA;MAOA DB08881|Vemurafenib BRAF;CYP1A2;CYP2D6;CYP3A4;CYP2C9;CYP2C8;CYP2B6;ALB;ORM1;ABCC1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;CYP2C9;CYP1A2;MAOA;CYP2D6;CYP2C8 2772:[DB09245 DB01084] DB09245|Toloxatone MAOA;MAOA DB01084|Emedastine HRH1 common genes common pathways 2773:[DB09245 DB11327] DB09245|Toloxatone MAOA;MAOA DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;NOS2 2774:[DB09245 DB14542] DB09245|Toloxatone MAOA;MAOA DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;HSD11B2;CYP3A5;HSD3B1;CYP11B1;CYP11B2;CYP3A7;MAOA;CYP3A4 2775:[DB09245 DB07288] DB09245|Toloxatone MAOA;MAOA DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways 2776:[DB09245 DB00541] DB09245|Toloxatone MAOA;MAOA DB00541|Vincristine TUBB;TUBA4A;CYP3A5;CYP3A7;CYP3A4;ABCB1;ABCC3;SLC22A3;ABCC1;ABCC10;ABCC2;ABCB11;ABCG2;RALBP1;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP3A7;CYP3A4 2777:[DB09245 DB11574] DB09245|Toloxatone MAOA;MAOA DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;MAOA;CYP3A7 2778:[DB09245 DB05212] DB09245|Toloxatone MAOA;MAOA DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2779:[DB09245 DB05944] DB09245|Toloxatone MAOA;MAOA DB05944|Varlitinib ERBB2;EGFR common genes common pathways 2780:[DB09245 DB05009] DB09245|Toloxatone MAOA;MAOA DB05009|Apadenoson ADORA2A common genes common pathways 2781:[DB09245 DB11828] DB09245|Toloxatone MAOA;MAOA DB11828|Neratinib EGFR;CYP3A4;FMO3;ALB;ORM1;ORM2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;FMO3 2782:[DB09245 DB05281] DB09245|Toloxatone MAOA;MAOA DB05281|S-8184 TUBA4A;BCL2 common genes common pathways 2783:[DB09245 DB08391] DB09245|Toloxatone MAOA;MAOA DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 2784:[DB09245 DB07775] DB09245|Toloxatone MAOA;MAOA DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways 2785:[DB09245 DB06439] DB09245|Toloxatone MAOA;MAOA DB06439|Tyloxapol LPL common genes common pathways 2786:[DB09245 DB12702] DB09245|Toloxatone MAOA;MAOA DB12702|Velusetrag HTR4 common genes common pathways 2787:[DB09245 DB03554] DB09245|Toloxatone MAOA;MAOA DB03554|5-Iodouracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;MAOA 2788:[DB09245 DB04356] DB09245|Toloxatone MAOA;MAOA DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2789:[DB09245 DB08056] DB09245|Toloxatone MAOA;MAOA DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways 2790:[DB09245 DB00376] DB09245|Toloxatone MAOA;MAOA DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 2791:[DB09245 DB07167] DB09245|Toloxatone MAOA;MAOA DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways 2792:[DB09245 DB01303] DB09245|Toloxatone MAOA;MAOA DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2793:[DB09245 DB08341] DB09245|Toloxatone MAOA;MAOA DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways 2794:[DB09245 DB13627] DB09245|Toloxatone MAOA;MAOA DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2795:[DB09245 DB05036] DB09245|Toloxatone MAOA;MAOA DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways 2796:[DB09245 DB07969] DB09245|Toloxatone MAOA;MAOA DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways 2797:[DB09245 DB04249] DB09245|Toloxatone MAOA;MAOA DB04249|Zinc Substituted Heme C CYCS common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYCS 2798:[DB09245 DB01890] DB09245|Toloxatone MAOA;MAOA DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways 2799:[DB09245 DB00535] DB09245|Toloxatone MAOA;MAOA DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;MPO 2800:[DB09245 DB05070] DB09245|Toloxatone MAOA;MAOA DB05070|ADX10059 GRM5 common genes common pathways 2801:[DB09245 DB05481] DB09245|Toloxatone MAOA;MAOA DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways 2802:[DB09245 DB13456] DB09245|Toloxatone MAOA;MAOA DB13456|Midecamycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2803:[DB09245 DB14520] DB09245|Toloxatone MAOA;MAOA DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways 2804:[DB09245 DB04991] DB09245|Toloxatone MAOA;MAOA DB04991|XL784 ADAM10 common genes common pathways 2805:[DB09245 DB11799] DB09245|Toloxatone MAOA;MAOA DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2806:[DB09245 DB00025] DB09245|Toloxatone MAOA;MAOA DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0055114| oxidation-reduction process PHYH;MAOA 2807:[DB09245 DB09211] DB09245|Toloxatone MAOA;MAOA DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways 2808:[DB09245 DB00219] DB09245|Toloxatone MAOA;MAOA DB00219|Oxyphenonium CHRM1 common genes common pathways 2809:[DB09245 DB06771] DB09245|Toloxatone MAOA;MAOA DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2810:[DB09245 DB01152] DB09245|Toloxatone MAOA;MAOA DB01152|Candicidin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2811:[DB09245 DB00354] DB09245|Toloxatone MAOA;MAOA DB00354|Buclizine HRH1;CHRM1 common genes common pathways 2812:[DB09245 DB05399] DB09245|Toloxatone MAOA;MAOA DB05399|Succinobucol VCAM1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;VCAM1 2813:[DB09245 DB11963] DB09245|Toloxatone MAOA;MAOA DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;MAOA;CYP2D6 2814:[DB09245 DB02698] DB09245|Toloxatone MAOA;MAOA DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways 2815:[DB09245 DB02918] DB09245|Toloxatone MAOA;MAOA DB02918|Zardaverine PDE4D common genes common pathways 2816:[DB09245 DB14512] DB09245|Toloxatone MAOA;MAOA DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA 2817:[DB09245 DB01752] DB09245|Toloxatone MAOA;MAOA DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways 2818:[DB09245 DB01970] DB09245|Toloxatone MAOA;MAOA DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways 2819:[DB09245 DB07162] DB09245|Toloxatone MAOA;MAOA DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways 2820:[DB09245 DB08257] DB09245|Toloxatone MAOA;MAOA DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways 2821:[DB09245 DB06626] DB09245|Toloxatone MAOA;MAOA DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A5;CYP3A4;CYP1A2;MAOA 2822:[DB09245 DB07991] DB09245|Toloxatone MAOA;MAOA DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways 2823:[DB09245 DB05298] DB09245|Toloxatone MAOA;MAOA DB05298|Tetomilast PDE4D common genes common pathways 2824:[DB09245 DB04339] DB09245|Toloxatone MAOA;MAOA DB04339|Carbocisteine GSTP1 common genes common pathways 2825:[DB09245 DB05101] DB09245|Toloxatone MAOA;MAOA DB05101|Matuzumab EGFR common genes common pathways 2826:[DB09245 DB06454] DB09245|Toloxatone MAOA;MAOA DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways 2827:[DB09245 DB08389] DB09245|Toloxatone MAOA;MAOA DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 2828:[DB09245 DB00677] DB09245|Toloxatone MAOA;MAOA DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2829:[DB09245 DB00136] DB09245|Toloxatone MAOA;MAOA DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP24A1 2830:[DB09245 DB05806] DB09245|Toloxatone MAOA;MAOA DB05806|Cositecan TOP1 common genes common pathways 2831:[DB09245 DB04633] DB09245|Toloxatone MAOA;MAOA DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways 2832:[DB09245 DB13926] DB09245|Toloxatone MAOA;MAOA DB13926|Cenegermin NTRK1 common genes common pathways 2833:[DB09245 DB11323] DB09245|Toloxatone MAOA;MAOA DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;MAOA;PTGS2 2834:[DB09245 DB03957] DB09245|Toloxatone MAOA;MAOA DB03957|SP2456 IL2 common genes common pathways 2835:[DB09245 DB14544] DB09245|Toloxatone MAOA;MAOA DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process HSD3B1;CYP3A5;HSD11B2;CYP2C8;MAOA;CYP3A7;CYP11B2;CYP11B1;CYP3A4 2836:[DB09245 DB14481] DB09245|Toloxatone MAOA;MAOA DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways 2837:[DB09245 DB08102] DB09245|Toloxatone MAOA;MAOA DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways 2838:[DB09245 DB07020] DB09245|Toloxatone MAOA;MAOA DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways 2839:[DB09245 DB05739] DB09245|Toloxatone MAOA;MAOA DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways 2840:[DB09245 DB09308] DB09245|Toloxatone MAOA;MAOA DB09308|Solithromycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2841:[DB09245 DB05966] DB09245|Toloxatone MAOA;MAOA DB05966|TAS-108 ESR1;ESR2 common genes common pathways 2842:[DB09245 DB04200] DB09245|Toloxatone MAOA;MAOA DB04200|Matairesinol DHRS4L2 common genes common pathways GO:0055114| oxidation-reduction process DHRS4L2;MAOA 2843:[DB09245 DB01167] DB09245|Toloxatone MAOA;MAOA DB01167|Itraconazole CYP51A1;CYP3A5;CYP3A7;CYP3A4;CYP2D6;CYP2B6;CYP1A1;CYP2E1;ABCB1;SLCO2B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP51A1;CYP3A7;CYP1A1;CYP2E1;CYP3A4;CYP2B6;CYP3A5;CYP2D6 2844:[DB09245 DB07306] DB09245|Toloxatone MAOA;MAOA DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 2845:[DB09245 DB05488] DB09245|Toloxatone MAOA;MAOA DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 2846:[DB09245 DB14541] DB09245|Toloxatone MAOA;MAOA DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP11B2;CYP11B1;MAOA;CYP3A7;CYP3A4;CYP2C8;HSD3B1;CYP3A5;HSD11B2 2847:[DB09245 DB03577] DB09245|Toloxatone MAOA;MAOA DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways 2848:[DB09245 DB06525] DB09245|Toloxatone MAOA;MAOA DB06525|Ganstigmine ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2849:[DB09245 DB00173] DB09245|Toloxatone MAOA;MAOA DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0055114| oxidation-reduction process PECR;MAOA 2850:[DB09245 DB00927] DB09245|Toloxatone MAOA;MAOA DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C19 2851:[DB09245 DB09006] DB09245|Toloxatone MAOA;MAOA DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways 2852:[DB09245 DB00979] DB09245|Toloxatone MAOA;MAOA DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways 2853:[DB09245 DB07577] DB09245|Toloxatone MAOA;MAOA DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways 2854:[DB09245 DB09369] DB09245|Toloxatone MAOA;MAOA DB09369|Polyestradiol phosphate ESR1 common genes common pathways 2855:[DB09245 DB08734] DB09245|Toloxatone MAOA;MAOA DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways 2856:[DB09245 DB09116] DB09245|Toloxatone MAOA;MAOA DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0055114| oxidation-reduction process CAT;MAOA;ALDH3B2 2857:[DB09245 DB09347] DB09245|Toloxatone MAOA;MAOA DB09347|Acetrizoic acid ALB common genes common pathways 2858:[DB09245 DB05029] DB09245|Toloxatone MAOA;MAOA DB05029|Lancovutide PLA2G4A common genes common pathways 2859:[DB09245 DB08369] DB09245|Toloxatone MAOA;MAOA DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2B6 2860:[DB09245 DB05876] DB09245|Toloxatone MAOA;MAOA DB05876|PDE4 PDE4A common genes common pathways 2861:[DB09245 DB02431] DB09245|Toloxatone MAOA;MAOA DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways 2862:[DB09245 DB14019] DB09245|Toloxatone MAOA;MAOA DB14019|Fosnetupitant CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2863:[DB09245 DB09059] DB09245|Toloxatone MAOA;MAOA DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways 2864:[DB09245 DB08805] DB09245|Toloxatone MAOA;MAOA DB08805|Metiamide HRH2 common genes common pathways 2865:[DB09245 DB00204] DB09245|Toloxatone MAOA;MAOA DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2866:[DB09245 DB05459] DB09245|Toloxatone MAOA;MAOA DB05459|Briakinumab IL12B;IL23A common genes common pathways 2867:[DB09245 DB13003] DB09245|Toloxatone MAOA;MAOA DB13003|Cortivazol NR3C1 common genes common pathways 2868:[DB09245 DB01956] DB09245|Toloxatone MAOA;MAOA DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways 2869:[DB09245 DB01780] DB09245|Toloxatone MAOA;MAOA DB01780|Fusicoccin YWHAE common genes common pathways 2870:[DB09245 DB04465] DB09245|Toloxatone MAOA;MAOA DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways 2871:[DB09245 DB01717] DB09245|Toloxatone MAOA;MAOA DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways 2872:[DB09245 DB07181] DB09245|Toloxatone MAOA;MAOA DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways 2873:[DB09245 DB00620] DB09245|Toloxatone MAOA;MAOA DB00620|Triamcinolone NR3C1;CYP3A4;PTGS2;BCHE;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;CYP3A4 2874:[DB09245 DB08078] DB09245|Toloxatone MAOA;MAOA DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways 2875:[DB09245 DB05867] DB09245|Toloxatone MAOA;MAOA DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 2876:[DB09245 DB12228] DB09245|Toloxatone MAOA;MAOA DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways 2877:[DB09245 DB03667] DB09245|Toloxatone MAOA;MAOA DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1 2878:[DB09245 DB02261] DB09245|Toloxatone MAOA;MAOA DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways 2879:[DB09245 DB00209] DB09245|Toloxatone MAOA;MAOA DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 2880:[DB09245 DB01963] DB09245|Toloxatone MAOA;MAOA DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways 2881:[DB09245 DB03359] DB09245|Toloxatone MAOA;MAOA DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2882:[DB09245 DB04978] DB09245|Toloxatone MAOA;MAOA DB04978|SP1049C TOP2A common genes common pathways 2883:[DB09245 DB05205] DB09245|Toloxatone MAOA;MAOA DB05205|CX157 MAOA common genes MAOA common pathways GO:0006576| cellular biogenic amine metabolic process MAOA GO:0055114| oxidation-reduction process MAOA GO:0042420| dopamine catabolic process MAOA GO:0006584| catecholamine metabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOA 2884:[DB09245 DB00673] DB09245|Toloxatone MAOA;MAOA DB00673|Aprepitant TACR1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A5;CYP3A7;MAOA;CYP3A4;CYP2C9 2885:[DB09245 DB04271] DB09245|Toloxatone MAOA;MAOA DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 2886:[DB09245 DB11714] DB09245|Toloxatone MAOA;MAOA DB11714|Durvalumab CD274;CD80 common genes common pathways 2887:[DB09245 DB03753] DB09245|Toloxatone MAOA;MAOA DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;MAOA 2888:[DB09245 DB14025] DB09245|Toloxatone MAOA;MAOA DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A2;MAOA;CYP2D6;CYP2C19 2889:[DB09245 DB14634] DB09245|Toloxatone MAOA;MAOA DB14634|Fluprednidene acetate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2890:[DB09245 DB04690] DB09245|Toloxatone MAOA;MAOA DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes common pathways 2891:[DB09245 DB02486] DB09245|Toloxatone MAOA;MAOA DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways 2892:[DB09245 DB06994] DB09245|Toloxatone MAOA;MAOA DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways 2893:[DB09245 DB00154] DB09245|Toloxatone MAOA;MAOA DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;PTGS1 2894:[DB09245 DB08908] DB09245|Toloxatone MAOA;MAOA DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways 2895:[DB09245 DB05104] DB09245|Toloxatone MAOA;MAOA DB05104|Asimadoline OPRK1 common genes common pathways 2896:[DB09245 DB05013] DB09245|Toloxatone MAOA;MAOA DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways 2897:[DB09245 DB04803] DB09245|Toloxatone MAOA;MAOA DB04803|Verdoheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;MAOA 2898:[DB09245 DB05706] DB09245|Toloxatone MAOA;MAOA DB05706|13-deoxydoxorubicin TOP2A common genes common pathways 2899:[DB09245 DB04487] DB09245|Toloxatone MAOA;MAOA DB04487|N-Methylleucine CXCL10 common genes common pathways 2900:[DB09245 DB11584] DB09245|Toloxatone MAOA;MAOA DB11584|Pipradrol DRD1;DRD5 common genes common pathways 2901:[DB09245 DB02123] DB09245|Toloxatone MAOA;MAOA DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways 2902:[DB09245 DB05890] DB09245|Toloxatone MAOA;MAOA DB05890|VEGF-AS VEGFA common genes common pathways 2903:[DB09245 DB07779] DB09245|Toloxatone MAOA;MAOA DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways 2904:[DB09245 DB12328] DB09245|Toloxatone MAOA;MAOA DB12328|Cantharidin AHR common genes common pathways 2905:[DB09245 DB08043] DB09245|Toloxatone MAOA;MAOA DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways 2906:[DB09245 DB00817] DB09245|Toloxatone MAOA;MAOA DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2907:[DB09245 DB07623] DB09245|Toloxatone MAOA;MAOA DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;MAOA 2908:[DB09245 DB07248] DB09245|Toloxatone MAOA;MAOA DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways 2909:[DB09245 DB05319] DB09245|Toloxatone MAOA;MAOA DB05319|Oportuzumab monatox EPCAM common genes common pathways 2910:[DB09245 DB09076] DB09245|Toloxatone MAOA;MAOA DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA 2911:[DB09245 DB08804] DB09245|Toloxatone MAOA;MAOA DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes MAOA common pathways GO:0055114| oxidation-reduction process MAOA;MAOB;CYP19A1 GO:0006576| cellular biogenic amine metabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOB;MAOA GO:0042420| dopamine catabolic process MAOB;MAOA GO:0006584| catecholamine metabolic process MAOA 2912:[DB09245 DB00977] DB09245|Toloxatone MAOA;MAOA DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8 2913:[DB09245 DB03796] DB09245|Toloxatone MAOA;MAOA DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA 2914:[DB09245 DB05187] DB09245|Toloxatone MAOA;MAOA DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways 2915:[DB09245 DB05838] DB09245|Toloxatone MAOA;MAOA DB05838|OPC-51803 AVPR2 common genes common pathways 2916:[DB09245 DB03107] DB09245|Toloxatone MAOA;MAOA DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways 2917:[DB09245 DB04454] DB09245|Toloxatone MAOA;MAOA DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways 2918:[DB09245 DB06080] DB09245|Toloxatone MAOA;MAOA DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways 2919:[DB09245 DB06642] DB09245|Toloxatone MAOA;MAOA DB06642|Bevasiranib VEGFA common genes common pathways 2920:[DB09245 DB11182] DB09245|Toloxatone MAOA;MAOA DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways 2921:[DB09245 DB07482] DB09245|Toloxatone MAOA;MAOA DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways 2922:[DB09245 DB04770] DB09245|Toloxatone MAOA;MAOA DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways 2923:[DB09245 DB06813] DB09245|Toloxatone MAOA;MAOA DB06813|Pralatrexate DHFR;TYMS;FPGS;SLC19A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 2924:[DB09245 DB09048] DB09245|Toloxatone MAOA;MAOA DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP2D6;MAOA;CYP2C9;CYP3A4 2925:[DB09245 DB08339] DB09245|Toloxatone MAOA;MAOA DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways 2926:[DB09245 DB05069] DB09245|Toloxatone MAOA;MAOA DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways 2927:[DB09245 DB06229] DB09245|Toloxatone MAOA;MAOA DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways 2928:[DB09245 DB05630] DB09245|Toloxatone MAOA;MAOA DB05630|Sodium stibogluconate TOP1 common genes common pathways 2929:[DB09245 DB02527] DB09245|Toloxatone MAOA;MAOA DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0055114| oxidation-reduction process MAOA;ABCC4 2930:[DB09245 DB07954] DB09245|Toloxatone MAOA;MAOA DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways 2931:[DB09245 DB11363] DB09245|Toloxatone MAOA;MAOA DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways 2932:[DB09245 DB05168] DB09245|Toloxatone MAOA;MAOA DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways 2933:[DB09245 DB08889] DB09245|Toloxatone MAOA;MAOA DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways 2934:[DB09245 DB00984] DB09245|Toloxatone MAOA;MAOA DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1 2935:[DB09245 DB11605] DB09245|Toloxatone MAOA;MAOA DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;CYP3A7;MAOA 2936:[DB09245 DB08602] DB09245|Toloxatone MAOA;MAOA DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways 2937:[DB09245 DB06728] DB09245|Toloxatone MAOA;MAOA DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 2938:[DB09245 DB00522] DB09245|Toloxatone MAOA;MAOA DB00522|Bentiromide HPN common genes common pathways 2939:[DB09245 DB02004] DB09245|Toloxatone MAOA;MAOA DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways 2940:[DB09245 DB00687] DB09245|Toloxatone MAOA;MAOA DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2941:[DB09245 DB05047] DB09245|Toloxatone MAOA;MAOA DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways 2942:[DB09245 DB07614] DB09245|Toloxatone MAOA;MAOA DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways 2943:[DB09245 DB03125] DB09245|Toloxatone MAOA;MAOA DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 2944:[DB09245 DB04714] DB09245|Toloxatone MAOA;MAOA DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways 2945:[DB09245 DB08795] DB09245|Toloxatone MAOA;MAOA DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 2946:[DB09245 DB09240] DB09245|Toloxatone MAOA;MAOA DB09240|Niludipine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2947:[DB09245 DB13421] DB09245|Toloxatone MAOA;MAOA DB13421|Edoxudine ALB common genes common pathways 2948:[DB09245 DB12023] DB09245|Toloxatone MAOA;MAOA DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways 2949:[DB09245 DB13879] DB09245|Toloxatone MAOA;MAOA DB13879|Glecaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP3A5;CYP3A43 2950:[DB09245 DB05423] DB09245|Toloxatone MAOA;MAOA DB05423|ORG-34517 NR3C1 common genes common pathways 2951:[DB09245 DB05415] DB09245|Toloxatone MAOA;MAOA DB05415|OSI-461 PDE5A common genes common pathways 2952:[DB09245 DB06896] DB09245|Toloxatone MAOA;MAOA DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways 2953:[DB09245 DB03981] DB09245|Toloxatone MAOA;MAOA DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways 2954:[DB09245 DB07968] DB09245|Toloxatone MAOA;MAOA DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways 2955:[DB09245 DB03987] DB09245|Toloxatone MAOA;MAOA DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 2956:[DB09245 DB04076] DB09245|Toloxatone MAOA;MAOA DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2957:[DB09245 DB05971] DB09245|Toloxatone MAOA;MAOA DB05971|Archexin AKT1 common genes common pathways 2958:[DB09245 DB12629] DB09245|Toloxatone MAOA;MAOA DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2959:[DB09245 DB06240] DB09245|Toloxatone MAOA;MAOA DB06240|Tariquidar ABCB1 common genes common pathways 2960:[DB09245 DB08856] DB09245|Toloxatone MAOA;MAOA DB08856|DADLE SLCO1B1 common genes common pathways 2961:[DB09245 DB07447] DB09245|Toloxatone MAOA;MAOA DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0055114| oxidation-reduction process AKR1D1;MAOA 2962:[DB09245 DB08729] DB09245|Toloxatone MAOA;MAOA DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways 2963:[DB09245 DB09037] DB09245|Toloxatone MAOA;MAOA DB09037|Pembrolizumab PDCD1 common genes common pathways 2964:[DB09245 DB11752] DB09245|Toloxatone MAOA;MAOA DB11752|Bryostatin 1 CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2965:[DB09245 DB08878] DB09245|Toloxatone MAOA;MAOA DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 2966:[DB09245 DB14146] DB09245|Toloxatone MAOA;MAOA DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways 2967:[DB09245 DB14029] DB09245|Toloxatone MAOA;MAOA DB14029|Furafylline CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 2968:[DB09245 DB09107] DB09245|Toloxatone MAOA;MAOA DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways 2969:[DB09245 DB03005] DB09245|Toloxatone MAOA;MAOA DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 2970:[DB09245 DB02831] DB09245|Toloxatone MAOA;MAOA DB02831|Dihydrogenphosphate DCXR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DCXR 2971:[DB09245 DB00649] DB09245|Toloxatone MAOA;MAOA DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes common pathways 2972:[DB09245 DB13200] DB09245|Toloxatone MAOA;MAOA DB13200|Lipegfilgrastim CSF3R common genes common pathways 2973:[DB09245 DB07406] DB09245|Toloxatone MAOA;MAOA DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways 2974:[DB09245 DB11952] DB09245|Toloxatone MAOA;MAOA DB11952|Duvelisib PIK3CG;PIK3CD;CYP3A4;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 2975:[DB09245 DB07369] DB09245|Toloxatone MAOA;MAOA DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways 2976:[DB09245 DB12742] DB09245|Toloxatone MAOA;MAOA DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways 2977:[DB09245 DB00317] DB09245|Toloxatone MAOA;MAOA DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP3A4;MAOA 2978:[DB09245 DB02240] DB09245|Toloxatone MAOA;MAOA DB02240|Quinacrine mustard TPR common genes common pathways 2979:[DB09245 DB08240] DB09245|Toloxatone MAOA;MAOA DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways 2980:[DB09245 DB06043] DB09245|Toloxatone MAOA;MAOA DB06043|Olaratumab PDGFRA common genes common pathways 2981:[DB09245 DB05964] DB09245|Toloxatone MAOA;MAOA DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways 2982:[DB09245 DB05129] DB09245|Toloxatone MAOA;MAOA DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways 2983:[DB09245 DB06663] DB09245|Toloxatone MAOA;MAOA DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 2984:[DB09245 DB07753] DB09245|Toloxatone MAOA;MAOA DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways 2985:[DB09245 DB00082] DB09245|Toloxatone MAOA;MAOA DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2C18;CYP4A11;MAOA;CYP27A1;CYP3A4 2986:[DB09245 DB01034] DB09245|Toloxatone MAOA;MAOA DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways GO:0055114| oxidation-reduction process MAOA;FASN 2987:[DB09245 DB07555] DB09245|Toloxatone MAOA;MAOA DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 2988:[DB09245 DB07011] DB09245|Toloxatone MAOA;MAOA DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 2989:[DB09245 DB03867] DB09245|Toloxatone MAOA;MAOA DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways GO:0055114| oxidation-reduction process MAOA;GSR 2990:[DB09245 DB01861] DB09245|Toloxatone MAOA;MAOA DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 2991:[DB09245 DB04557] DB09245|Toloxatone MAOA;MAOA DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA;PTGS1 2992:[DB09245 DB09300] DB09245|Toloxatone MAOA;MAOA DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways 2993:[DB09245 DB02082] DB09245|Toloxatone MAOA;MAOA DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways 2994:[DB09245 DB05831] DB09245|Toloxatone MAOA;MAOA DB05831|ING-1 EPCAM common genes common pathways 2995:[DB09245 DB06995] DB09245|Toloxatone MAOA;MAOA DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways 2996:[DB09245 DB07479] DB09245|Toloxatone MAOA;MAOA DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways 2997:[DB09245 DB06199] DB09245|Toloxatone MAOA;MAOA DB06199|Atrasentan EDNRA common genes common pathways 2998:[DB09245 DB08130] DB09245|Toloxatone MAOA;MAOA DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways 2999:[DB09245 DB00028] DB09245|Toloxatone MAOA;MAOA DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways 3000:[DB09245 DB04622] DB09245|Toloxatone MAOA;MAOA DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways 3001:[DB09245 DB14057] DB09245|Toloxatone MAOA;MAOA DB14057|Valinomycin ABCB11 common genes common pathways 3002:[DB09245 DB06900] DB09245|Toloxatone MAOA;MAOA DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways 3003:[DB09245 DB00218] DB09245|Toloxatone MAOA;MAOA DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 3004:[DB09245 DB08842] DB09245|Toloxatone MAOA;MAOA DB08842|Acetylcarnitine SLC22A5 common genes common pathways 3005:[DB09245 DB03708] DB09245|Toloxatone MAOA;MAOA DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways 3006:[DB09245 DB05199] DB09245|Toloxatone MAOA;MAOA DB05199|LX1031 TPH1 common genes common pathways GO:0055114| oxidation-reduction process TPH1;MAOA 3007:[DB09245 DB01103] DB09245|Toloxatone MAOA;MAOA DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP3A5 3008:[DB09245 DB05882] DB09245|Toloxatone MAOA;MAOA DB05882|CHF 4227 ESR1;ESR2 common genes common pathways 3009:[DB09245 DB08249] DB09245|Toloxatone MAOA;MAOA DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 3010:[DB09245 DB13165] DB09245|Toloxatone MAOA;MAOA DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways 3011:[DB09245 DB03346] DB09245|Toloxatone MAOA;MAOA DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways 3012:[DB09245 DB07208] DB09245|Toloxatone MAOA;MAOA DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways 3013:[DB09245 DB09093] DB09245|Toloxatone MAOA;MAOA DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways 3014:[DB09245 DB07744] DB09245|Toloxatone MAOA;MAOA DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways 3015:[DB09245 DB05642] DB09245|Toloxatone MAOA;MAOA DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways 3016:[DB09245 DB08584] DB09245|Toloxatone MAOA;MAOA DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways 3017:[DB09245 DB04859] DB09245|Toloxatone MAOA;MAOA DB04859|Zanapezil ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 3018:[DB09245 DB00245] DB09245|Toloxatone MAOA;MAOA DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;MAOA GO:0042420| dopamine catabolic process SLC6A3;MAOA 3019:[DB09245 DB00792] DB09245|Toloxatone MAOA;MAOA DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 3020:[DB09245 DB14070] DB09245|Toloxatone MAOA;MAOA DB14070|HM-30181 ABCB1 common genes common pathways 3021:[DB09245 DB07115] DB09245|Toloxatone MAOA;MAOA DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 3022:[DB09245 DB03477] DB09245|Toloxatone MAOA;MAOA DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 3023:[DB09245 DB05295] DB09245|Toloxatone MAOA;MAOA DB05295|Eldecalcitol VDR common genes common pathways 3024:[DB09245 DB08566] DB09245|Toloxatone MAOA;MAOA DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 3025:[DB09245 DB03878] DB09245|Toloxatone MAOA;MAOA DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways 3026:[DB09245 DB05131] DB09245|Toloxatone MAOA;MAOA DB05131|TTP889 F9 common genes common pathways 3027:[DB09245 DB07328] DB09245|Toloxatone MAOA;MAOA DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways 3028:[DB09245 DB03434] DB09245|Toloxatone MAOA;MAOA DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways 3029:[DB09245 DB00429] DB09245|Toloxatone MAOA;MAOA DB00429|Carboprost tromethamine PTGER1 common genes common pathways 3030:[DB09245 DB07899] DB09245|Toloxatone MAOA;MAOA DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways 3031:[DB09245 DB00981] DB09245|Toloxatone MAOA;MAOA DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 3032:[DB09245 DB05507] DB09245|Toloxatone MAOA;MAOA DB05507|VX-765 CASP1;IL1B common genes common pathways 3033:[DB09245 DB08879] DB09245|Toloxatone MAOA;MAOA DB08879|Belimumab TNFSF13B common genes common pathways 3034:[DB09245 DB02134] DB09245|Toloxatone MAOA;MAOA DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 3035:[DB09245 DB07846] DB09245|Toloxatone MAOA;MAOA DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 3036:[DB09245 DB06550] DB09245|Toloxatone MAOA;MAOA DB06550|Bivatuzumab CD44 common genes common pathways 3037:[DB09245 DB05804] DB09245|Toloxatone MAOA;MAOA DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;PTGS2;CYP3A7;MAOA 3038:[DB09245 DB00970] DB09245|Toloxatone MAOA;MAOA DB00970|Dactinomycin TOP2A;TOP2B;SLC22A5;ABCB1;ABCC6;ABCC1;ABCG2 common genes common pathways 3039:[DB09245 DB07430] DB09245|Toloxatone MAOA;MAOA DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways 3040:[DB09245 DB13074] DB09245|Toloxatone MAOA;MAOA DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3041:[DB09245 DB03639] DB09245|Toloxatone MAOA;MAOA DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways 3042:[DB09245 DB11133] DB09245|Toloxatone MAOA;MAOA DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;ALOX5 3043:[DB09245 DB04537] DB09245|Toloxatone MAOA;MAOA DB04537|L-Tryptophanamide trpS;WARS common genes common pathways 3044:[DB09245 DB13934] DB09245|Toloxatone MAOA;MAOA DB13934|Ligandrol AR common genes common pathways 3045:[DB09245 DB04985] DB09245|Toloxatone MAOA;MAOA DB04985|Tigapotide RPSA common genes common pathways 3046:[DB09245 DB05141] DB09245|Toloxatone MAOA;MAOA DB05141|LY2181308 BIRC5 common genes common pathways 3047:[DB09245 DB12301] DB09245|Toloxatone MAOA;MAOA DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP3A4 3048:[DB09245 DB04398] DB09245|Toloxatone MAOA;MAOA DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways 3049:[DB09245 DB13174] DB09245|Toloxatone MAOA;MAOA DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2E1;CYP3A4;CYP1A2;MAOA;CYP3A7;CYP2D6;CYP3A5;CYP3A43;ALOX5 3050:[DB09245 DB11359] DB09245|Toloxatone MAOA;MAOA DB11359|Guaiacol ALB common genes common pathways 3051:[DB09245 DB07161] DB09245|Toloxatone MAOA;MAOA DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways 3052:[DB09245 DB03677] DB09245|Toloxatone MAOA;MAOA DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways 3053:[DB09245 DB08009] DB09245|Toloxatone MAOA;MAOA DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways 3054:[DB09245 DB02530] DB09245|Toloxatone MAOA;MAOA DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways 3055:[DB09245 DB05879] DB09245|Toloxatone MAOA;MAOA DB05879|AME-527 TNF common genes common pathways 3056:[DB09245 DB11186] DB09245|Toloxatone MAOA;MAOA DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes common pathways 3057:[DB09245 DB08828] DB09245|Toloxatone MAOA;MAOA DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;MAOA;CYP2C9;CYP3A4 3058:[DB09245 DB08325] DB09245|Toloxatone MAOA;MAOA DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways 3059:[DB09245 DB07449] DB09245|Toloxatone MAOA;MAOA DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 3060:[DB09245 DB07933] DB09245|Toloxatone MAOA;MAOA DB07933|Erteberel ESR2;ESR1 common genes common pathways 3061:[DB09245 DB09085] DB09245|Toloxatone MAOA;MAOA DB09085|Tetracaine RYR1;RYR2 common genes common pathways 3062:[DB09245 DB06560] DB09245|Toloxatone MAOA;MAOA DB06560|Pascolizumab IL4 common genes common pathways 3063:[DB09245 DB05889] DB09245|Toloxatone MAOA;MAOA DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways 3064:[DB09245 DB05367] DB09245|Toloxatone MAOA;MAOA DB05367|Actelion-1 EDNRA common genes common pathways 3065:[DB09245 DB00719] DB09245|Toloxatone MAOA;MAOA DB00719|Azatadine HRH1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3066:[DB09245 DB08499] DB09245|Toloxatone MAOA;MAOA DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways 3067:[DB09245 DB01013] DB09245|Toloxatone MAOA;MAOA DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;MAOA 3068:[DB09245 DB08880] DB09245|Toloxatone MAOA;MAOA DB08880|Teriflunomide DHODH;CYP2C8;CYP1A2;ABCG2;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP2C8;MAOA;CYP1A2 3069:[DB09245 DB04868] DB09245|Toloxatone MAOA;MAOA DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP2C9;CYP3A4;CYP2B6;MAOA 3070:[DB09245 DB12020] DB09245|Toloxatone MAOA;MAOA DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways 3071:[DB09245 DB06235] DB09245|Toloxatone MAOA;MAOA DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 3072:[DB09245 DB04971] DB09245|Toloxatone MAOA;MAOA DB04971|Reglixane PPARA;PPARG common genes common pathways 3073:[DB09245 DB14066] DB09245|Toloxatone MAOA;MAOA DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3074:[DB09245 DB00337] DB09245|Toloxatone MAOA;MAOA DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3075:[DB09245 DB00203] DB09245|Toloxatone MAOA;MAOA DB00203|Sildenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2D6;CYP1A1;CYP2E1;ABCC4;ABCC5;ABCC10;SLCO1B1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A7;CYP1A1;CYP2C9;CYP2E1;CYP3A4;ABCC4;CYP3A5;CYP2C19;CYP2D6 3076:[DB09245 DB01177] DB09245|Toloxatone MAOA;MAOA DB01177|Idarubicin TOP2A;CYP2C9;CYP2D6;ABCC1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA;CYP2D6 3077:[DB09245 DB01042] DB09245|Toloxatone MAOA;MAOA DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways 3078:[DB09245 DB05297] DB09245|Toloxatone MAOA;MAOA DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways 3079:[DB09245 DB03738] DB09245|Toloxatone MAOA;MAOA DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 3080:[DB09245 DB08890] DB09245|Toloxatone MAOA;MAOA DB08890|Linaclotide GUCY2C common genes common pathways 3081:[DB09245 DB11134] DB09245|Toloxatone MAOA;MAOA DB11134|Cupric oxide ALB;CP common genes common pathways GO:0055114| oxidation-reduction process CP;MAOA 3082:[DB09245 DB07285] DB09245|Toloxatone MAOA;MAOA DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 3083:[DB09245 DB03390] DB09245|Toloxatone MAOA;MAOA DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways 3084:[DB09245 DB07419] DB09245|Toloxatone MAOA;MAOA DB07419|S-23 AR common genes common pathways 3085:[DB09245 DB04689] DB09245|Toloxatone MAOA;MAOA DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways 3086:[DB09245 DB04577] DB09245|Toloxatone MAOA;MAOA DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways 3087:[DB09245 DB07069] DB09245|Toloxatone MAOA;MAOA DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 3088:[DB09245 DB07728] DB09245|Toloxatone MAOA;MAOA DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 3089:[DB09245 DB00509] DB09245|Toloxatone MAOA;MAOA DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;TPO 3090:[DB09245 DB11118] DB09245|Toloxatone MAOA;MAOA DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways 3091:[DB09245 DB01809] DB09245|Toloxatone MAOA;MAOA DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways 3092:[DB09245 DB01549] DB09245|Toloxatone MAOA;MAOA DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways 3093:[DB09245 DB06788] DB09245|Toloxatone MAOA;MAOA DB06788|Histrelin GNRHR common genes common pathways 3094:[DB09245 DB03612] DB09245|Toloxatone MAOA;MAOA DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0055114| oxidation-reduction process MAOA;HADH 3095:[DB09245 DB02457] DB09245|Toloxatone MAOA;MAOA DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways GO:0055114| oxidation-reduction process MAOA;LIPF 3096:[DB09245 DB04057] DB09245|Toloxatone MAOA;MAOA DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways 3097:[DB09245 DB08831] DB09245|Toloxatone MAOA;MAOA DB08831|2-deoxyglucose SLC2A1 common genes common pathways 3098:[DB09245 DB12323] DB09245|Toloxatone MAOA;MAOA DB12323|Radotinib ABL1 common genes common pathways 3099:[DB09245 DB01840] DB09245|Toloxatone MAOA;MAOA DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways 3100:[DB09245 DB02358] DB09245|Toloxatone MAOA;MAOA DB02358|LY374571 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;MTHFD1 3101:[DB09245 DB12483] DB09245|Toloxatone MAOA;MAOA DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;CYP3A7;MAOA 3102:[DB09245 DB04864] DB09245|Toloxatone MAOA;MAOA DB04864|Huperzine A ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 3103:[DB09245 DB11693] DB09245|Toloxatone MAOA;MAOA DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 3104:[DB09245 DB06834] DB09245|Toloxatone MAOA;MAOA DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways 3105:[DB09245 DB00161] DB09245|Toloxatone MAOA;MAOA DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways 3106:[DB09245 DB06612] DB09245|Toloxatone MAOA;MAOA DB06612|Mepolizumab IL5 common genes common pathways 3107:[DB09245 DB05152] DB09245|Toloxatone MAOA;MAOA DB05152|NGX267 CHRM1 common genes common pathways 3108:[DB09245 DB11529] DB09245|Toloxatone MAOA;MAOA DB11529|Melengestrol CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3109:[DB09245 DB01931] DB09245|Toloxatone MAOA;MAOA DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways 3110:[DB09245 DB04954] DB09245|Toloxatone MAOA;MAOA DB04954|Tecadenoson ADORA1 common genes common pathways 3111:[DB09245 DB02659] DB09245|Toloxatone MAOA;MAOA DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process ADH1C;ABCC4;MT-CO2;MAOA;MT-CO1 3112:[DB09245 DB05110] DB09245|Toloxatone MAOA;MAOA DB05110|VIR201 IFNG common genes common pathways 3113:[DB09245 DB06194] DB09245|Toloxatone MAOA;MAOA DB06194|Elocalcitol VDR common genes common pathways 3114:[DB09245 DB12116] DB09245|Toloxatone MAOA;MAOA DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways 3115:[DB09245 DB02104] DB09245|Toloxatone MAOA;MAOA DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;MAOA 3116:[DB09245 DB05846] DB09245|Toloxatone MAOA;MAOA DB05846|Mito-4509 APP common genes common pathways 3117:[DB09245 DB08802] DB09245|Toloxatone MAOA;MAOA DB08802|Isothipendyl HRH1 common genes common pathways 3118:[DB09245 DB02035] DB09245|Toloxatone MAOA;MAOA DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways 3119:[DB09245 DB00307] DB09245|Toloxatone MAOA;MAOA DB00307|Bexarotene RXRA;RXRB;RXRG;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4;CYP2C9 3120:[DB09245 DB04891] DB09245|Toloxatone MAOA;MAOA DB04891|Becocalcidiol MED1;VDR common genes common pathways 3121:[DB09245 DB02597] DB09245|Toloxatone MAOA;MAOA DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways 3122:[DB09245 DB02309] DB09245|Toloxatone MAOA;MAOA DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 3123:[DB09245 DB02547] DB09245|Toloxatone MAOA;MAOA DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 3124:[DB09245 DB06429] DB09245|Toloxatone MAOA;MAOA DB06429|Talnetant TACR3 common genes common pathways 3125:[DB09245 DB00644] DB09245|Toloxatone MAOA;MAOA DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways 3126:[DB09245 DB04927] DB09245|Toloxatone MAOA;MAOA DB04927|NM100060 SQLE common genes common pathways GO:0055114| oxidation-reduction process MAOA;SQLE 3127:[DB09245 DB14543] DB09245|Toloxatone MAOA;MAOA DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP11B1;CYP11B2;CYP3A7;MAOA;CYP3A4;CYP2C8;CYP3A5;HSD11B2;HSD3B1 3128:[DB09245 DB07641] DB09245|Toloxatone MAOA;MAOA DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes MAOA common pathways GO:0055114| oxidation-reduction process MAOA GO:0006576| cellular biogenic amine metabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0006584| catecholamine metabolic process MAOA GO:0042420| dopamine catabolic process MAOA 3129:[DB09245 DB04235] DB09245|Toloxatone MAOA;MAOA DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0042135| neurotransmitter catabolic process ABAT;MAOA 3130:[DB09245 DB00389] DB09245|Toloxatone MAOA;MAOA DB00389|Carbimazole TPO;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;TPO;MAOA 3131:[DB09245 DB01164] DB09245|Toloxatone MAOA;MAOA DB01164|Calcium Chloride S100A13 common genes common pathways 3132:[DB09245 DB08703] DB09245|Toloxatone MAOA;MAOA DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways 3133:[DB09245 DB01482] DB09245|Toloxatone MAOA;MAOA DB01482|Fenethylline CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 3134:[DB09245 DB11772] DB09245|Toloxatone MAOA;MAOA DB11772|Pilaralisib PIK3CA common genes common pathways 3135:[DB09245 DB14067] DB09245|Toloxatone MAOA;MAOA DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways 3136:[DB09245 DB09568] DB09245|Toloxatone MAOA;MAOA DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP4F2;HSD17B10;CYP3A4;HADH;CYP3A7;MAOA 3137:[DB09245 DB11994] DB09245|Toloxatone MAOA;MAOA DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;ALOX5;CYP3A43;CYP2C9;CYP2E1;CYP3A4;CYP1A2;MAOA;CYP3A7 3138:[DB09245 DB05903] DB09245|Toloxatone MAOA;MAOA DB05903|KOS-1584 CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3139:[DB09245 DB04556] DB09245|Toloxatone MAOA;MAOA DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 3140:[DB09245 DB06436] DB09245|Toloxatone MAOA;MAOA DB06436|Semaxanib KDR;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOA 3141:[DB09245 DB04970] DB09245|Toloxatone MAOA;MAOA DB04970|Lesopitron HTR1A common genes common pathways 3142:[DB09245 DB01319] DB09245|Toloxatone MAOA;MAOA DB01319|Fosamprenavir pol;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3143:[DB09245 DB06867] DB09245|Toloxatone MAOA;MAOA DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways 3144:[DB09245 DB07412] DB09245|Toloxatone MAOA;MAOA DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways 3145:[DB09245 DB01681] DB09245|Toloxatone MAOA;MAOA DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways 3146:[DB09245 DB08492] DB09245|Toloxatone MAOA;MAOA DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways GO:0055114| oxidation-reduction process ALOX15;MAOA 3147:[DB09245 DB01285] DB09245|Toloxatone MAOA;MAOA DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP27B1;HSD3B2;MAOA;CYP3A4;CYP24A1 3148:[DB09245 DB08896] DB09245|Toloxatone MAOA;MAOA DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2B6;CYP3A4;CYP2C9;CYP2C8 3149:[DB09245 DB08651] DB09245|Toloxatone MAOA;MAOA DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways 3150:[DB09245 DB07271] DB09245|Toloxatone MAOA;MAOA DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways 3151:[DB09245 DB00277] DB09245|Toloxatone MAOA;MAOA DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP1B1;CYP1A1;CYP2E1;CYP3A4;CYP1A2;MAOA 3152:[DB09245 DB03181] DB09245|Toloxatone MAOA;MAOA DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways 3153:[DB09245 DB09302] DB09245|Toloxatone MAOA;MAOA DB09302|Alirocumab PCSK9 common genes common pathways 3154:[DB09245 DB03906] DB09245|Toloxatone MAOA;MAOA DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;HMOX1 3155:[DB09245 DB13044] DB09245|Toloxatone MAOA;MAOA DB13044|Gossypol BCL2L1 common genes common pathways 3156:[DB09245 DB12789] DB09245|Toloxatone MAOA;MAOA DB12789|Dinoprost PTGDR2 common genes common pathways 3157:[DB09245 DB01852] DB09245|Toloxatone MAOA;MAOA DB01852|Kaempherol UGT3A1 common genes common pathways 3158:[DB09245 DB02235] DB09245|Toloxatone MAOA;MAOA DB02235|L-methionine (R)-S-oxide APP common genes common pathways 3159:[DB09245 DB03551] DB09245|Toloxatone MAOA;MAOA DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways 3160:[DB09245 DB05010] DB09245|Toloxatone MAOA;MAOA DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways 3161:[DB09245 DB05374] DB09245|Toloxatone MAOA;MAOA DB05374|Rindopepimut EGFR common genes common pathways 3162:[DB09245 DB00089] DB09245|Toloxatone MAOA;MAOA DB00089|Capromab pendetide FOLH1 common genes common pathways 3163:[DB09245 DB04583] DB09245|Toloxatone MAOA;MAOA DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 3164:[DB09245 DB01675] DB09245|Toloxatone MAOA;MAOA DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways GO:0055114| oxidation-reduction process ACAD8;MAOA 3165:[DB09245 DB07457] DB09245|Toloxatone MAOA;MAOA DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways 3166:[DB09245 DB07970] DB09245|Toloxatone MAOA;MAOA DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways 3167:[DB09245 DB07051] DB09245|Toloxatone MAOA;MAOA DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways 3168:[DB09245 DB08207] DB09245|Toloxatone MAOA;MAOA DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways 3169:[DB09245 DB06795] DB09245|Toloxatone MAOA;MAOA DB06795|Mafenide CA6 common genes common pathways 3170:[DB09245 DB05854] DB09245|Toloxatone MAOA;MAOA DB05854|CLX-0921 PPARG common genes common pathways 3171:[DB09245 DB00986] DB09245|Toloxatone MAOA;MAOA DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways 3172:[DB09245 DB05443] DB09245|Toloxatone MAOA;MAOA DB05443|ADL 10-0101 OPRK1 common genes common pathways 3173:[DB09245 DB05098] DB09245|Toloxatone MAOA;MAOA DB05098|Leptin LEPR common genes common pathways 3174:[DB09245 DB09101] DB09245|Toloxatone MAOA;MAOA DB09101|Elvitegravir pol;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3175:[DB09245 DB12202] DB09245|Toloxatone MAOA;MAOA DB12202|Zalutumumab EGFR common genes common pathways 3176:[DB09245 DB01281] DB09245|Toloxatone MAOA;MAOA DB01281|Abatacept CD80;CD86 common genes common pathways 3177:[DB09245 DB00361] DB09245|Toloxatone MAOA;MAOA DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6 3178:[DB09245 DB12140] DB09245|Toloxatone MAOA;MAOA DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways 3179:[DB09245 DB08520] DB09245|Toloxatone MAOA;MAOA DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways 3180:[DB09245 DB02054] DB09245|Toloxatone MAOA;MAOA DB02054|Gabaculine OAT common genes common pathways 3181:[DB09245 DB00495] DB09245|Toloxatone MAOA;MAOA DB00495|Zidovudine pol;TERT;CYP2A6;CYP2C8;CYP2C9;CYP3A4;TK1;UGT2B7;UGT1A1;ALB;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLC28A1;SLC29A2;ABCB1;ABCC4;ABCC5;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9;CYP3A4;CYP2A6;ABCC4;CYP2C8 3182:[DB09245 DB05294] DB09245|Toloxatone MAOA;MAOA DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;FMO1;FMO3;MAOA 3183:[DB09245 DB02884] DB09245|Toloxatone MAOA;MAOA DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways 3184:[DB09245 DB04845] DB09245|Toloxatone MAOA;MAOA DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3185:[DB09245 DB08575] DB09245|Toloxatone MAOA;MAOA DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways 3186:[DB09245 DB06413] DB09245|Toloxatone MAOA;MAOA DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0042420| dopamine catabolic process MAOA;SLC6A3 GO:0055114| oxidation-reduction process CYP2C19;CYP3A5;CYP1A2;MAOA;CYP2B6;CYP2C9;CYP3A4 3187:[DB09245 DB08085] DB09245|Toloxatone MAOA;MAOA DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways 3188:[DB09245 DB08356] DB09245|Toloxatone MAOA;MAOA DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways 3189:[DB09245 DB00544] DB09245|Toloxatone MAOA;MAOA DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;DPYD;CYP2C8;MTHFR;CYP1A2;MAOA;CYP2A6;CYP2C9 3190:[DB09245 DB12391] DB09245|Toloxatone MAOA;MAOA DB12391|Sagopilone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3191:[DB09245 DB13261] DB09245|Toloxatone MAOA;MAOA DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 3192:[DB09245 DB01790] DB09245|Toloxatone MAOA;MAOA DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways 3193:[DB09245 DB08565] DB09245|Toloxatone MAOA;MAOA DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 3194:[DB09245 DB07749] DB09245|Toloxatone MAOA;MAOA DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways 3195:[DB09245 DB09120] DB09245|Toloxatone MAOA;MAOA DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP1A2;MAOA;CYP2E1;CYP2C9 3196:[DB09245 DB06116] DB09245|Toloxatone MAOA;MAOA DB06116|Eldelumab CXCL10 common genes common pathways 3197:[DB09245 DB05848] DB09245|Toloxatone MAOA;MAOA DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways 3198:[DB09245 DB04036] DB09245|Toloxatone MAOA;MAOA DB04036|Coenzyme a Persulfide IVD common genes common pathways GO:0055114| oxidation-reduction process IVD;MAOA 3199:[DB09245 DB07240] DB09245|Toloxatone MAOA;MAOA DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways 3200:[DB09245 DB00143] DB09245|Toloxatone MAOA;MAOA DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0055114| oxidation-reduction process GLRX2;GPX1;ABCC4;GSTO2;GPX6;GSTK1;GPX2;MGST1;TXNDC12;GSR;MAOA;GPX4;GLRX;GPX5;AKR1B1;GPX3;CYP3A4;GSTO1;GPX8;GPX7 3201:[DB09245 DB03176] DB09245|Toloxatone MAOA;MAOA DB03176|KB-141 THRB;THRA common genes common pathways 3202:[DB09245 DB08870] DB09245|Toloxatone MAOA;MAOA DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3203:[DB09245 DB01785] DB09245|Toloxatone MAOA;MAOA DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways 3204:[DB09245 DB14039] DB09245|Toloxatone MAOA;MAOA DB14039|Erenumab CALCRL common genes common pathways 3205:[DB09245 DB03683] DB09245|Toloxatone MAOA;MAOA DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 3206:[DB09245 DB03393] DB09245|Toloxatone MAOA;MAOA DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways 3207:[DB09245 DB01025] DB09245|Toloxatone MAOA;MAOA DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways 3208:[DB09245 DB03744] DB09245|Toloxatone MAOA;MAOA DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways 3209:[DB09245 DB08873] DB09245|Toloxatone MAOA;MAOA DB08873|Boceprevir CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP3A4 3210:[DB09245 DB01613] DB09245|Toloxatone MAOA;MAOA DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways 3211:[DB09245 DB01878] DB09245|Toloxatone MAOA;MAOA DB01878|Benzophenone ESR1;ESR2 common genes common pathways 3212:[DB09245 DB03070] DB09245|Toloxatone MAOA;MAOA DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;IMPDH2 3213:[DB09245 DB06089] DB09245|Toloxatone MAOA;MAOA DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways 3214:[DB09245 DB00012] DB09245|Toloxatone MAOA;MAOA DB00012|Darbepoetin alfa EPOR common genes common pathways 3215:[DB09245 DB03929] DB09245|Toloxatone MAOA;MAOA DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways 3216:[DB09245 DB00201] DB09245|Toloxatone MAOA;MAOA DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C8;CYP3A5 3217:[DB09245 DB08100] DB09245|Toloxatone MAOA;MAOA DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways 3218:[DB09245 DB04924] DB09245|Toloxatone MAOA;MAOA DB04924|Itopride DRD2;ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process MAOA;ACHE 3219:[DB09245 DB12455] DB09245|Toloxatone MAOA;MAOA DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways 3220:[DB09245 DB04322] DB09245|Toloxatone MAOA;MAOA DB04322|LY249543 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;MTHFD1 3221:[DB09245 DB04575] DB09245|Toloxatone MAOA;MAOA DB04575|Quinestrol ESR1 common genes common pathways 3222:[DB09245 DB06350] DB09245|Toloxatone MAOA;MAOA DB06350|Elinogrel P2RY12 common genes common pathways 3223:[DB09245 DB08039] DB09245|Toloxatone MAOA;MAOA DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways 3224:[DB09245 DB13985] DB09245|Toloxatone MAOA;MAOA DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways 3225:[DB09245 DB04615] DB09245|Toloxatone MAOA;MAOA DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0042135| neurotransmitter catabolic process ACHE;MAOA 3226:[DB09245 DB04376] DB09245|Toloxatone MAOA;MAOA DB04376|13-Acetylphorbol PRKCD common genes common pathways 3227:[DB09245 DB07021] DB09245|Toloxatone MAOA;MAOA DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways 3228:[DB09245 DB07202] DB09245|Toloxatone MAOA;MAOA DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways 3229:[DB09245 DB08791] DB09245|Toloxatone MAOA;MAOA DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways 3230:[DB09245 DB00107] DB09245|Toloxatone MAOA;MAOA DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways 3231:[DB09245 DB00659] DB09245|Toloxatone MAOA;MAOA DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways 3232:[DB09245 DB01609] DB09245|Toloxatone MAOA;MAOA DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;MAOA;CYP3A4 3233:[DB09245 DB05540] DB09245|Toloxatone MAOA;MAOA DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways 3234:[DB09245 DB00239] DB09245|Toloxatone MAOA;MAOA DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;MAOA;CYP3A4 3235:[DB09245 DB00666] DB09245|Toloxatone MAOA;MAOA DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways 3236:[DB09245 DB06719] DB09245|Toloxatone MAOA;MAOA DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;MAOA 3237:[DB09245 DB14487] DB09245|Toloxatone MAOA;MAOA DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0055114| oxidation-reduction process PDIA3;P4HB;MAOA;SOD1;GAPDHS;CCS;PRDX1;CP;ADH1C 3238:[DB09245 DB00026] DB09245|Toloxatone MAOA;MAOA DB00026|Anakinra IL1R1 common genes common pathways 3239:[DB09245 DB05490] DB09245|Toloxatone MAOA;MAOA DB05490|T131 PPARG common genes common pathways 3240:[DB09245 DB11217] DB09245|Toloxatone MAOA;MAOA DB11217|Arbutin TYR;ALB common genes common pathways GO:0055114| oxidation-reduction process MAOA;TYR 3241:[DB09245 DB03541] DB09245|Toloxatone MAOA;MAOA DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process DHRS4L1;MAOA;NQO2 3242:[DB09245 DB05992] DB09245|Toloxatone MAOA;MAOA DB05992|Plinabulin TNF common genes common pathways 3243:[DB09245 DB00184] DB09245|Toloxatone MAOA;MAOA DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes MAOA common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2;MAOB;CYP3A4;CYP19A1;CYP2C9;CYP1A1;CYP2E1;CYP2A13;CYP2A6;CYP2B6;CYP2D6;CYP2C19;CYP2C8 GO:0006576| cellular biogenic amine metabolic process MAOA GO:0042133| neurotransmitter metabolic process MAOA GO:0042135| neurotransmitter catabolic process MAOB;MAOA GO:0042420| dopamine catabolic process MAOB;MAOA GO:0006584| catecholamine metabolic process MAOA 3244:[DB09245 DB06777] DB09245|Toloxatone MAOA;MAOA DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways GO:0055114| oxidation-reduction process AKR1C2;MAOA;CYP3A4;CYP27A1 3245:[DB09245 DB08479] DB09245|Toloxatone MAOA;MAOA DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways 3246:[DB09245 DB04630] DB09245|Toloxatone MAOA;MAOA DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP11B1;CYP11B2;MAOA;CYP3A4 3247:[DB09245 DB11591] DB09245|Toloxatone MAOA;MAOA DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways 3248:[DB09245 DB05352] DB09245|Toloxatone MAOA;MAOA DB05352|Fx-1006A TTR common genes common pathways 3249:[DB09245 DB05969] DB09245|Toloxatone MAOA;MAOA DB05969|SNS-032 CDK7;VEGFA common genes common pathways 3250:[DB09245 DB00809] DB09245|Toloxatone MAOA;MAOA DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways 3251:[DB09245 DB00648] DB09245|Toloxatone MAOA;MAOA DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP11B1;FDX1 3252:[DB09245 DB02047] DB09245|Toloxatone MAOA;MAOA DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1 3253:[DB09245 DB04879] DB09245|Toloxatone MAOA;MAOA DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways 3254:[DB09245 DB02303] DB09245|Toloxatone MAOA;MAOA DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways GO:0055114| oxidation-reduction process MAOA;DPYD 3255:[DB09245 DB00004] DB09245|Toloxatone MAOA;MAOA DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways 3256:[DB09245 DB05461] DB09245|Toloxatone MAOA;MAOA DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways 3257:[DB09245 DB02901] DB09245|Toloxatone MAOA;MAOA DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1;CYP11A1;HSD17B1;CYP17A1 3258:[DB09245 DB04838] DB09245|Toloxatone MAOA;MAOA DB04838|Cyclandelate CACNA2D1;CES1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3259:[DB09245 DB06202] DB09245|Toloxatone MAOA;MAOA DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes common pathways 3260:[DB09245 DB08798] DB09245|Toloxatone MAOA;MAOA DB08798|Sulfamoxole CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA 3261:[DB09245 DB05905] DB09245|Toloxatone MAOA;MAOA DB05905|TD-2749 HTR4 common genes common pathways 3262:[DB09245 DB00496] DB09245|Toloxatone MAOA;MAOA DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2D6 3263:[DB09245 DB04070] DB09245|Toloxatone MAOA;MAOA DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3264:[DB09245 DB00807] DB09245|Toloxatone MAOA;MAOA DB00807|Proparacaine SCN10A common genes common pathways 3265:[DB09245 DB00443] DB09245|Toloxatone MAOA;MAOA DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1;CYP3A4 3266:[DB09245 DB01972] DB09245|Toloxatone MAOA;MAOA DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0055114| oxidation-reduction process GMPR;MAOA 3267:[DB09245 DB01217] DB09245|Toloxatone MAOA;MAOA DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP19A1;CYP3A4;CYP1A2;MAOA 3268:[DB09245 DB05662] DB09245|Toloxatone MAOA;MAOA DB05662|NP-50301 ESR1 common genes common pathways 3269:[DB09245 DB05511] DB09245|Toloxatone MAOA;MAOA DB05511|Piclidenoson ADORA3 common genes common pathways 3270:[DB09245 DB06879] DB09245|Toloxatone MAOA;MAOA DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;MAOA 3271:[DB09245 DB07637] DB09245|Toloxatone MAOA;MAOA DB07637|Dibromotyrosine EPOR common genes common pathways 3272:[DB09245 DB06791] DB09245|Toloxatone MAOA;MAOA DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3273:[DB09245 DB03158] DB09245|Toloxatone MAOA;MAOA DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways 3274:[DB09245 DB05202] DB09245|Toloxatone MAOA;MAOA DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways 3275:[DB09245 DB01062] DB09245|Toloxatone MAOA;MAOA DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C8;CYP2D6;CYP3A5 3276:[DB09245 DB05188] DB09245|Toloxatone MAOA;MAOA DB05188|KD3010 PPARD common genes common pathways 3277:[DB09245 DB06820] DB09245|Toloxatone MAOA;MAOA DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP1A2;MAOA 3278:[DB09245 DB13869] DB09245|Toloxatone MAOA;MAOA DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways 3279:[DB09245 DB02820] DB09245|Toloxatone MAOA;MAOA DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways GO:0055114| oxidation-reduction process MAOA;HSD17B10 3280:[DB09245 DB00223] DB09245|Toloxatone MAOA;MAOA DB00223|Diflorasone NR3C1 common genes common pathways 3281:[DB09245 DB02481] DB09245|Toloxatone MAOA;MAOA DB02481|N-Benzylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;MAOA 3282:[DB09245 DB00106] DB09245|Toloxatone MAOA;MAOA DB00106|Abarelix GNRHR common genes common pathways 3283:[DB09245 DB14062] DB09245|Toloxatone MAOA;MAOA DB14062|Concanamycin A ABCB1 common genes common pathways 3284:[DB09245 DB14514] DB09245|Toloxatone MAOA;MAOA DB14514|Magnesium levulinate ATP1A1 common genes common pathways 3285:[DB09245 DB04278] DB09245|Toloxatone MAOA;MAOA DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways 3286:[DB09245 DB04787] DB09245|Toloxatone MAOA;MAOA DB04787|Tanaproget PGR common genes common pathways 3287:[DB09245 DB07675] DB09245|Toloxatone MAOA;MAOA DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways 3288:[DB09245 DB05038] DB09245|Toloxatone MAOA;MAOA DB05038|Anatibant BDKRB2 common genes common pathways 3289:[DB09245 DB13975] DB09245|Toloxatone MAOA;MAOA DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP1A2;MAOA;CYP2C9;CYP3A4 3290:[DB09245 DB06213] DB09245|Toloxatone MAOA;MAOA DB06213|Regadenoson ADORA2A common genes common pathways 3291:[DB09245 DB09327] DB09245|Toloxatone MAOA;MAOA DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;MAOA;DPYD 3292:[DB09245 DB08386] DB09245|Toloxatone MAOA;MAOA DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 3293:[DB09245 DB00891] DB09245|Toloxatone MAOA;MAOA DB00891|Sulfapyridine CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA 3294:[DB09245 DB04655] DB09245|Toloxatone MAOA;MAOA DB04655|Metoprine HNMT common genes common pathways 3295:[DB09245 DB08744] DB09245|Toloxatone MAOA;MAOA DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways GO:0055114| oxidation-reduction process NQO2;MAOA 3296:[DB09245 DB04253] DB09245|Toloxatone MAOA;MAOA DB04253|Tretazicar NQO2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NQO2 3297:[DB09245 DB06314] DB09245|Toloxatone MAOA;MAOA DB06314|SGX-523 MET common genes common pathways 3298:[DB09245 DB11811] DB09245|Toloxatone MAOA;MAOA DB11811|Arhalofenate PPARG common genes common pathways 3299:[DB09245 DB05259] DB09245|Toloxatone MAOA;MAOA DB05259|Glatiramer HLA-DRB1 common genes common pathways 3300:[DB09245 DB11254] DB09245|Toloxatone MAOA;MAOA DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0055114| oxidation-reduction process TYR;MAOA 3301:[DB09245 DB14700] DB09245|Toloxatone MAOA;MAOA DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0055114| oxidation-reduction process F8;MAOA 3302:[DB09245 DB09381] DB09245|Toloxatone MAOA;MAOA DB09381|Estrogens, esterified CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3303:[DB09245 DB06752] DB09245|Toloxatone MAOA;MAOA DB06752|Chymopapain PRG2 common genes common pathways 3304:[DB09245 DB09095] DB09245|Toloxatone MAOA;MAOA DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3305:[DB09245 DB06558] DB09245|Toloxatone MAOA;MAOA DB06558|Tezosentan EDNRA;EDNRB common genes common pathways 3306:[DB09245 DB13915] DB09245|Toloxatone MAOA;MAOA DB13915|Axicabtagene ciloleucel CD19 common genes common pathways 3307:[DB09245 DB00428] DB09245|Toloxatone MAOA;MAOA DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP1A1;MAOA;CYP1A2 3308:[DB09245 DB05793] DB09245|Toloxatone MAOA;MAOA DB05793|PRO-542 FFAR4 common genes common pathways 3309:[DB09245 DB00387] DB09245|Toloxatone MAOA;MAOA DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways 3310:[DB09245 DB11718] DB09245|Toloxatone MAOA;MAOA DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C19;CYP2D6 3311:[DB09245 DB05133] DB09245|Toloxatone MAOA;MAOA DB05133|VP025 IL1B common genes common pathways 3312:[DB09245 DB03742] DB09245|Toloxatone MAOA;MAOA DB03742|Compound 4-D ESR1 common genes common pathways 3313:[DB09245 DB01269] DB09245|Toloxatone MAOA;MAOA DB01269|Panitumumab EGFR common genes common pathways 3314:[DB09245 DB09126] DB09245|Toloxatone MAOA;MAOA DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways 3315:[DB09245 DB05369] DB09245|Toloxatone MAOA;MAOA DB05369|HZT-501 HRH2 common genes common pathways 3316:[DB09245 DB09054] DB09245|Toloxatone MAOA;MAOA DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A7;CYP2B6;AOX1;CYP3A4;CYP3A43;CYP2C19;CYP2C8;CYP3A5 3317:[DB09245 DB04703] DB09245|Toloxatone MAOA;MAOA DB04703|Hesperidin AURKB common genes common pathways 3318:[DB09245 DB06825] DB09245|Toloxatone MAOA;MAOA DB06825|Triptorelin GNRHR common genes common pathways 3319:[DB09245 DB01941] DB09245|Toloxatone MAOA;MAOA DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways 3320:[DB09245 DB01611] DB09245|Toloxatone MAOA;MAOA DB01611|Hydroxychloroquine TLR7;TLR9;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2D6 3321:[DB09245 DB09270] DB09245|Toloxatone MAOA;MAOA DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process NDUFV3;MAOA;HMGCR;SDHA 3322:[DB09245 DB12406] DB09245|Toloxatone MAOA;MAOA DB12406|Lisofylline CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 3323:[DB09245 DB07393] DB09245|Toloxatone MAOA;MAOA DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways GO:0055114| oxidation-reduction process GSR;MAOA 3324:[DB09245 DB01839] DB09245|Toloxatone MAOA;MAOA DB01839|Propylene glycol F13A1 common genes common pathways 3325:[DB09245 DB05675] DB09245|Toloxatone MAOA;MAOA DB05675|EP-2104R FGA common genes common pathways 3326:[DB09245 DB02262] DB09245|Toloxatone MAOA;MAOA DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 3327:[DB09245 DB03222] DB09245|Toloxatone MAOA;MAOA DB03222|dATP POLB;recA;recA common genes common pathways 3328:[DB09245 DB04776] DB09245|Toloxatone MAOA;MAOA DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways 3329:[DB09245 DB07379] DB09245|Toloxatone MAOA;MAOA DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways 3330:[DB09245 DB07645] DB09245|Toloxatone MAOA;MAOA DB07645|SEBACIC ACID HBA1;HBB common genes common pathways 3331:[DB09245 DB04660] DB09245|Toloxatone MAOA;MAOA DB04660|Choline alfoscerate GM2A common genes common pathways 3332:[DB09245 DB00073] DB09245|Toloxatone MAOA;MAOA DB00073|Rituximab MS4A1 common genes common pathways 3333:[DB09245 DB06494] DB09245|Toloxatone MAOA;MAOA DB06494|Sufugolix GNRHR common genes common pathways 3334:[DB09245 DB07108] DB09245|Toloxatone MAOA;MAOA DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways 3335:[DB09245 DB08642] DB09245|Toloxatone MAOA;MAOA DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHFR 3336:[DB09245 DB09409] DB09245|Toloxatone MAOA;MAOA DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways 3337:[DB09245 DB00048] DB09245|Toloxatone MAOA;MAOA DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways 3338:[DB09245 DB05239] DB09245|Toloxatone MAOA;MAOA DB05239|Cobimetinib MAP2K1;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3339:[DB09245 DB02703] DB09245|Toloxatone MAOA;MAOA DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;MAOA 3340:[DB09245 DB00518] DB09245|Toloxatone MAOA;MAOA DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;MAOA;CYP1A2;CYP2C19 3341:[DB09245 DB13835] DB09245|Toloxatone MAOA;MAOA DB13835|Caroverine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3342:[DB09245 DB01699] DB09245|Toloxatone MAOA;MAOA DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0042135| neurotransmitter catabolic process ABAT;MAOA 3343:[DB09245 DB01196] DB09245|Toloxatone MAOA;MAOA DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3344:[DB09245 DB06937] DB09245|Toloxatone MAOA;MAOA DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways 3345:[DB09245 DB08169] DB09245|Toloxatone MAOA;MAOA DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;MAOA 3346:[DB09245 DB06263] DB09245|Toloxatone MAOA;MAOA DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0055114| oxidation-reduction process MAOA;POR;CBR1 3347:[DB09245 DB03725] DB09245|Toloxatone MAOA;MAOA DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways 3348:[DB09245 DB00426] DB09245|Toloxatone MAOA;MAOA DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process AOX1;CYP3A4;MAOA 3349:[DB09245 DB14545] DB09245|Toloxatone MAOA;MAOA DB14545|Hydrocortisone succinate CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP11B1;CYP11B2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A7;CYP11B2;CYP11B1;CYP3A5;CYP2C8 3350:[DB09245 DB02165] DB09245|Toloxatone MAOA;MAOA DB02165|Zinc Trihydroxide GSTM1 common genes common pathways 3351:[DB09245 DB02824] DB09245|Toloxatone MAOA;MAOA DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways 3352:[DB09245 DB06757] DB09245|Toloxatone MAOA;MAOA DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0055114| oxidation-reduction process IDH3G;IDH3A;MAOA 3353:[DB09245 DB00121] DB09245|Toloxatone MAOA;MAOA DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;MAOA 3354:[DB09245 DB05432] DB09245|Toloxatone MAOA;MAOA DB05432|DAS-431 IV CALY common genes common pathways 3355:[DB09245 DB13125] DB09245|Toloxatone MAOA;MAOA DB13125|Lusutrombopag MPL;CYP4A11;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP4A11 3356:[DB09245 DB01201] DB09245|Toloxatone MAOA;MAOA DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP2D6;CYP2C19;CYP2C8;MAOA;CYP2B6;CYP3A4;CYP2C9 3357:[DB09245 DB04901] DB09245|Toloxatone MAOA;MAOA DB04901|Galiximab CD80 common genes common pathways 3358:[DB09245 DB06393] DB09245|Toloxatone MAOA;MAOA DB06393|Xaliproden HTR1A common genes common pathways 3359:[DB09245 DB01117] DB09245|Toloxatone MAOA;MAOA DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;MT-CYB;MAOA;DHODH 3360:[DB09245 DB12582] DB09245|Toloxatone MAOA;MAOA DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2C9 3361:[DB09245 DB04213] DB09245|Toloxatone MAOA;MAOA DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways 3362:[DB09245 DB07232] DB09245|Toloxatone MAOA;MAOA DB07232|Veliparib PARP1;PARP2 common genes common pathways 3363:[DB09245 DB08262] DB09245|Toloxatone MAOA;MAOA DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways 3364:[DB09245 DB05122] DB09245|Toloxatone MAOA;MAOA DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways 3365:[DB09245 DB04065] DB09245|Toloxatone MAOA;MAOA DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0055114| oxidation-reduction process MAOA;ADH1A 3366:[DB09245 DB08689] DB09245|Toloxatone MAOA;MAOA DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways GO:0055114| oxidation-reduction process SDHC;SDHA;SDHD;MAOA;SDHB 3367:[DB09245 DB05079] DB09245|Toloxatone MAOA;MAOA DB05079|HY10275 HRH1;HTR2A common genes common pathways 3368:[DB09245 DB05403] DB09245|Toloxatone MAOA;MAOA DB05403|CEP-1347 MAPK12 common genes common pathways 3369:[DB09245 DB05961] DB09245|Toloxatone MAOA;MAOA DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways 3370:[DB09245 DB04982] DB09245|Toloxatone MAOA;MAOA DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways 3371:[DB09245 DB11386] DB09245|Toloxatone MAOA;MAOA DB11386|Chlorobutanol KCNH2 common genes common pathways 3372:[DB09245 DB06021] DB09245|Toloxatone MAOA;MAOA DB06021|AV-412 EGFR;ERBB2 common genes common pathways 3373:[DB09245 DB04869] DB09245|Toloxatone MAOA;MAOA DB04869|Olcegepant CALCA;CALCRL common genes common pathways 3374:[DB09245 DB00932] DB09245|Toloxatone MAOA;MAOA DB00932|Tipranavir pol;CYP3A4;CYP2D6;CYP2C19;UGT1A1;ABCB11;SLCO2B1;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;MAOA;CYP3A4 3375:[DB09245 DB13951] DB09245|Toloxatone MAOA;MAOA DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP11A1;MAOA;CYP17A1;HSD17B1 3376:[DB09245 DB14003] DB09245|Toloxatone MAOA;MAOA DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP4F2;MAOA;CYP3A4 3377:[DB09245 DB09161] DB09245|Toloxatone MAOA;MAOA DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes common pathways 3378:[DB09245 DB00141] DB09245|Toloxatone MAOA;MAOA DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways 3379:[DB09245 DB03904] DB09245|Toloxatone MAOA;MAOA DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways 3380:[DB09245 DB07177] DB09245|Toloxatone MAOA;MAOA DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGR2;PTGR1 3381:[DB09245 DB03793] DB09245|Toloxatone MAOA;MAOA DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0055114| oxidation-reduction process DAO;MAOA;PRDX5 3382:[DB09245 DB06273] DB09245|Toloxatone MAOA;MAOA DB06273|Tocilizumab IL6R;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3383:[DB09245 DB08232] DB09245|Toloxatone MAOA;MAOA DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways 3384:[DB09245 DB02731] DB09245|Toloxatone MAOA;MAOA DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways 3385:[DB09245 DB07984] DB09245|Toloxatone MAOA;MAOA DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS1 3386:[DB09245 DB06480] DB09245|Toloxatone MAOA;MAOA DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3387:[DB09245 DB04216] DB09245|Toloxatone MAOA;MAOA DB04216|Quercetin HCK;PIK3CG;UGT3A1;ATP5B;PIM1;HIBCH;fabZ;STK17B;ESR1;ESR2;NQO2;AHR;CYP1B1;ACTB;CSNK2A1;CSNK2B;EIF3F;HSP90AA1;HSPA2;RUVBL2;SF3B3;UBA1;SHBG;CBR1;CEBPB;NR1I2;CYP2C8;ALB;ABCC1;ABCC2;SLC16A7;SLCO2B1;ABCB1;SLC16A1;ABCG2;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process NQO2;MAOA;CYP2C8;CBR1;CYP1B1 3388:[DB09245 DB07983] DB09245|Toloxatone MAOA;MAOA DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;MAOA 3389:[DB09245 DB07769] DB09245|Toloxatone MAOA;MAOA DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways 3390:[DB09245 DB07454] DB09245|Toloxatone MAOA;MAOA DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways 3391:[DB09245 DB00170] DB09245|Toloxatone MAOA;MAOA DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process VKORC1L1;AOX1;CYP2A6;NQO1;CYP2E1;CYP1A1;XDH;MTHFR;NQO2;VKORC1;MAOA;CYP1A2 3392:[DB09245 DB08577] DB09245|Toloxatone MAOA;MAOA DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways 3393:[DB09245 DB00065] DB09245|Toloxatone MAOA;MAOA DB00065|Infliximab TNF common genes common pathways 3394:[DB09245 DB05214] DB09245|Toloxatone MAOA;MAOA DB05214|KD7040 NOS2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;NOS2 3395:[DB09245 DB13857] DB09245|Toloxatone MAOA;MAOA DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3396:[DB09245 DB00587] DB09245|Toloxatone MAOA;MAOA DB00587|Cinalukast CYSLTR1 common genes common pathways 3397:[DB09245 DB05939] DB09245|Toloxatone MAOA;MAOA DB05939|MK-0354 GPER1 common genes common pathways 3398:[DB09245 DB06168] DB09245|Toloxatone MAOA;MAOA DB06168|Canakinumab IL1B common genes common pathways 3399:[DB09245 DB00272] DB09245|Toloxatone MAOA;MAOA DB00272|Betazole HRH2 common genes common pathways 3400:[DB09245 DB12662] DB09245|Toloxatone MAOA;MAOA DB12662|Naveglitazar PPARG common genes common pathways 3401:[DB09245 DB09147] DB09245|Toloxatone MAOA;MAOA DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways 3402:[DB09245 DB00109] DB09245|Toloxatone MAOA;MAOA DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;MAOA;CYP2E1 3403:[DB09245 DB02371] DB09245|Toloxatone MAOA;MAOA DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways 3404:[DB09245 DB02028] DB09245|Toloxatone MAOA;MAOA DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways 3405:[DB09245 DB07209] DB09245|Toloxatone MAOA;MAOA DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways 3406:[DB09245 DB08583] DB09245|Toloxatone MAOA;MAOA DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways 3407:[DB09245 DB00646] DB09245|Toloxatone MAOA;MAOA DB00646|Nystatin CYP3A4;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3408:[DB09245 DB01195] DB09245|Toloxatone MAOA;MAOA DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA;CYP2C9 3409:[DB09245 DB11071] DB09245|Toloxatone MAOA;MAOA DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;MAOA;PTGS2 3410:[DB09245 DB08191] DB09245|Toloxatone MAOA;MAOA DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways 3411:[DB09245 DB13257] DB09245|Toloxatone MAOA;MAOA DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes common pathways GO:0055114| oxidation-reduction process TPH1;CP;MPO;PTGS1;RRM1;FTH1;P4HA1;PCBD1;SUOX;CAT;XDH;MAOA;CYP4A11;PTGS2;NDUFS8;NOS2;SDHA;TMLHE 3412:[DB09245 DB00056] DB09245|Toloxatone MAOA;MAOA DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 3413:[DB09245 DB08478] DB09245|Toloxatone MAOA;MAOA DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways 3414:[DB09245 DB07931] DB09245|Toloxatone MAOA;MAOA DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0055114| oxidation-reduction process AKR1C1;MAOA 3415:[DB09245 DB01827] DB09245|Toloxatone MAOA;MAOA DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways 3416:[DB09245 DB11219] DB09245|Toloxatone MAOA;MAOA DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways 3417:[DB09245 DB03732] DB09245|Toloxatone MAOA;MAOA DB03732|Etheno-Nadp BST1 common genes common pathways 3418:[DB09245 DB08970] DB09245|Toloxatone MAOA;MAOA DB08970|Fluprednidene CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3419:[DB09245 DB03382] DB09245|Toloxatone MAOA;MAOA DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways GO:0055114| oxidation-reduction process SOD1;MAOA 3420:[DB09245 DB08790] DB09245|Toloxatone MAOA;MAOA DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways 3421:[DB09245 DB03935] DB09245|Toloxatone MAOA;MAOA DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways 3422:[DB09245 DB00027] DB09245|Toloxatone MAOA;MAOA DB00027|Gramicidin D ABCB1 common genes common pathways 3423:[DB09245 DB01746] DB09245|Toloxatone MAOA;MAOA DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways 3424:[DB09245 DB01259] DB09245|Toloxatone MAOA;MAOA DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP3A5;CYP2C19;CYP2C8 3425:[DB09245 DB09031] DB09245|Toloxatone MAOA;MAOA DB09031|Miltefosine ABCB1;PLD1 common genes common pathways 3426:[DB09245 DB08429] DB09245|Toloxatone MAOA;MAOA DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways 3427:[DB09245 DB01406] DB09245|Toloxatone MAOA;MAOA DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;MAOA 3428:[DB09245 DB00862] DB09245|Toloxatone MAOA;MAOA DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP3A5 3429:[DB09245 DB09552] DB09245|Toloxatone MAOA;MAOA DB09552|Thonzonium ATP6V1C1 common genes common pathways 3430:[DB09245 DB03480] DB09245|Toloxatone MAOA;MAOA DB03480|Brequinar Analog DHODH common genes common pathways GO:0055114| oxidation-reduction process MAOA;DHODH 3431:[DB09245 DB00448] DB09245|Toloxatone MAOA;MAOA DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C8;CYP2C19;CYP2C18 3432:[DB09245 DB06708] DB09245|Toloxatone MAOA;MAOA DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;MAOA;CYP3A4 3433:[DB09245 DB05035] DB09245|Toloxatone MAOA;MAOA DB05035|Eprotirome THRA;THRB common genes common pathways 3434:[DB09245 DB06729] DB09245|Toloxatone MAOA;MAOA DB06729|Sulfaphenazole CYP2C9;CYP2B6;CYP2C8;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;MAOA;CYP2D6;CYP2C8 3435:[DB09245 DB11079] DB09245|Toloxatone MAOA;MAOA DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOA;PTGS1 3436:[DB09245 DB02300] DB09245|Toloxatone MAOA;MAOA DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;MPO;MAOA 3437:[DB09245 DB08313] DB09245|Toloxatone MAOA;MAOA DB08313|nocodazole HPGDS common genes common pathways 3438:[DB09245 DB12747] DB09245|Toloxatone MAOA;MAOA DB12747|Tertomotide TERT common genes common pathways 3439:[DB09245 DB13170] DB09245|Toloxatone MAOA;MAOA DB13170|Plecanatide GUCY1A2 common genes common pathways 3440:[DB09245 DB01073] DB09245|Toloxatone MAOA;MAOA DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process RRM1;MAOA 3441:[DB09245 DB03983] DB09245|Toloxatone MAOA;MAOA DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways GO:0055114| oxidation-reduction process SUOX;MAOA 3442:[DB09245 DB00092] DB09245|Toloxatone MAOA;MAOA DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways 3443:[DB09245 DB13983] DB09245|Toloxatone MAOA;MAOA DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways 3444:[DB09245 DB08383] DB09245|Toloxatone MAOA;MAOA DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways 3445:[DB09245 DB00990] DB09245|Toloxatone MAOA;MAOA DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP19A1;CYP3A4 3446:[DB09245 DB02895] DB09245|Toloxatone MAOA;MAOA DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways GO:0055114| oxidation-reduction process GSR;MAOA 3447:[DB09245 DB11750] DB09245|Toloxatone MAOA;MAOA DB11750|Clobetasol CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3448:[DB09245 DB06766] DB09245|Toloxatone MAOA;MAOA DB06766|Alcaftadine HRH1 common genes common pathways 3449:[DB09245 DB02967] DB09245|Toloxatone MAOA;MAOA DB02967|N-Ethylmaleimide CLC common genes common pathways 3450:[DB09245 DB05207] DB09245|Toloxatone MAOA;MAOA DB05207|SD118 TNF;IL1R1 common genes common pathways 3451:[DB09245 DB06677] DB09245|Toloxatone MAOA;MAOA DB06677|Clazosentan EDNRA common genes common pathways 3452:[DB09245 DB04258] DB09245|Toloxatone MAOA;MAOA DB04258|Seocalcitol VDR common genes common pathways 3453:[DB09245 DB01188] DB09245|Toloxatone MAOA;MAOA DB01188|Ciclopirox ATP1A1 common genes common pathways 3454:[DB09245 DB11737] DB09245|Toloxatone MAOA;MAOA DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP1A2;CYP3A4 3455:[DB09245 DB06548] DB09245|Toloxatone MAOA;MAOA DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways 3456:[DB09245 DB09297] DB09245|Toloxatone MAOA;MAOA DB09297|Paritaprevir CYP3A4;CYP3A5;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;MAOA;CYP3A4 3457:[DB09245 DB04372] DB09245|Toloxatone MAOA;MAOA DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 3458:[DB09245 DB00905] DB09245|Toloxatone MAOA;MAOA DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0055114| oxidation-reduction process AKR1C3;MAOA 3459:[DB09245 DB00466] DB09245|Toloxatone MAOA;MAOA DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;MAOA 3460:[DB09245 DB01078] DB09245|Toloxatone MAOA;MAOA DB01078|Deslanoside ATP1A1 common genes common pathways 3461:[DB09245 DB11945] DB09245|Toloxatone MAOA;MAOA DB11945|Avelumab CD274 common genes common pathways 3462:[DB09245 DB01786] DB09245|Toloxatone MAOA;MAOA DB01786|D-Alanine SLC16A10 common genes common pathways 3463:[DB09245 DB04451] DB09245|Toloxatone MAOA;MAOA DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways 3464:[DB09245 DB06258] DB09245|Toloxatone MAOA;MAOA DB06258|Bimoclomol HSF1 common genes common pathways 3465:[DB09245 DB01260] DB09245|Toloxatone MAOA;MAOA DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 3466:[DB09245 DB05624] DB09245|Toloxatone MAOA;MAOA DB05624|Teverelix GNRHR common genes common pathways 3467:[DB09245 DB04020] DB09245|Toloxatone MAOA;MAOA DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways 3468:[DB09245 DB05119] DB09245|Toloxatone MAOA;MAOA DB05119|Rilapladib PLA2G7 common genes common pathways 3469:[DB09245 DB07723] DB09245|Toloxatone MAOA;MAOA DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways 3470:[DB09245 DB08038] DB09245|Toloxatone MAOA;MAOA DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 3471:[DB09245 DB04711] DB09245|Toloxatone MAOA;MAOA DB04711|Iodipamide ALB common genes common pathways 3472:[DB09245 DB03510] DB09245|Toloxatone MAOA;MAOA DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways 3473:[DB09245 DB06681] DB09245|Toloxatone MAOA;MAOA DB06681|Belatacept CD86;CD80 common genes common pathways 3474:[DB09245 DB04664] DB09245|Toloxatone MAOA;MAOA DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2B6 3475:[DB09245 DB06897] DB09245|Toloxatone MAOA;MAOA DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways 3476:[DB09245 DB05150] DB09245|Toloxatone MAOA;MAOA DB05150|CAD106 APP common genes common pathways 3477:[DB09245 DB01381] DB09245|Toloxatone MAOA;MAOA DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;MAOA 3478:[DB09245 DB01208] DB09245|Toloxatone MAOA;MAOA DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;MAOA 3479:[DB09245 DB04150] DB09245|Toloxatone MAOA;MAOA DB04150|Threonine Derivative PAM common genes common pathways GO:0055114| oxidation-reduction process MAOA;PAM 3480:[DB09245 DB04716] DB09245|Toloxatone MAOA;MAOA DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways 3481:[DB09245 DB01003] DB09245|Toloxatone MAOA;MAOA DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways 3482:[DB09245 DB05311] DB09245|Toloxatone MAOA;MAOA DB05311|Ecallantide KLKB1 common genes common pathways 3483:[DB09245 DB11597] DB09245|Toloxatone MAOA;MAOA DB11597|Human Rho(D) immune globulin RHD common genes common pathways 3484:[DB09245 DB07033] DB09245|Toloxatone MAOA;MAOA DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways 3485:[DB09245 DB00778] DB09245|Toloxatone MAOA;MAOA DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;MAOA 3486:[DB09245 DB00022] DB09245|Toloxatone MAOA;MAOA DB00022|Peginterferon alfa-2b IFNAR1;IFNAR2;CYP1A2;CYP2D6;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A2;MAOA;CYP2D6 3487:[DB09245 DB03408] DB09245|Toloxatone MAOA;MAOA DB03408|gamma-Glutamylcysteine GSS common genes common pathways 3488:[DB09245 DB01830] DB09245|Toloxatone MAOA;MAOA DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways 3489:[DB09245 DB11475] DB09245|Toloxatone MAOA;MAOA DB11475|Tylosin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 3490:[DB09245 DB08933] DB09245|Toloxatone MAOA;MAOA DB08933|Luliconazole CYP3A4;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C19 3491:[DB09245 DB05465] DB09245|Toloxatone MAOA;MAOA DB05465|Tandutinib FLT3;PDGFD common genes common pathways 3492:[DB09245 DB11632] DB09245|Toloxatone MAOA;MAOA DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes common pathways GO:0006584| catecholamine metabolic process COMT;MAOA GO:0042420| dopamine catabolic process COMT;MAOA GO:0042135| neurotransmitter catabolic process MAOA;COMT GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;MAOA 3493:[DB09245 DB02676] DB09245|Toloxatone MAOA;MAOA DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways 3494:[DB09245 DB02555] DB09245|Toloxatone MAOA;MAOA DB02555|SP4160 IL2 common genes common pathways 3495:[DB09245 DB08891] DB09245|Toloxatone MAOA;MAOA DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways 3496:[DB09245 DB01884] DB09245|Toloxatone MAOA;MAOA DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways 3497:[DB09245 DB06160] DB09245|Toloxatone MAOA;MAOA DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP1A2 3498:[DB09245 DB04839] DB09245|Toloxatone MAOA;MAOA DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;MAOA 3499:[DB09245 DB03881] DB09245|Toloxatone MAOA;MAOA DB03881|MT-Immucillin-H PNP common genes common pathways 3500:[DB09245 DB14040] DB09245|Toloxatone MAOA;MAOA DB14040|Eptinezumab CALCA;CALCB common genes common pathways 3501:[DB09245 DB01949] DB09245|Toloxatone MAOA;MAOA DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 3502:[DB06616 DB07543] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ADRB2 GO:0045453| bone resorption SRC;ADRB2 3503:[DB06616 DB00504] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00504|Levallorphan OPRM1 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0007165| signal transduction OPRM1;LYN;SRC;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ABL1;MAP2K2;SRC;MAP2K1 3504:[DB06616 DB00413] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0010628| positive regulation of gene expression DRD1;MAP2K1;SRC GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A;HTR2B;HTR2A GO:0009636| response to toxin LYN;HTR1D;DRD2 GO:0008283| cell proliferation HTR1A;SRC GO:0000187| activation of MAPK activity DRD4;ADRA2B;MAP3K2;MAP2K2;MAP2K1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0055085| transmembrane transport ABCB1;SLC22A2;SLC22A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;SRC;DRD2;MAP2K2;MAP2K1;ABL1;HTR2C;HTR2B GO:0050715| positive regulation of cytokine secretion HTR2B;SRC GO:1903351| ABL1;DRD1 GO:0030900| forebrain development SRC;DRD2 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0007165| signal transduction BCR;HTR1B;SRC;DRD2;MAP2K1;DRD5;HTR2B;HTR2C;ADRA2A;DRD1;HTR1D;HTR1A;DRD4;ADRA2C;HTR2A;LYN;ADRA2B;DRD3 GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0030335| positive regulation of cell migration ADRA2A;DRD1;LYN GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;HTR2B;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0030168| platelet activation SRC;ADRA2A;ADRA2C;LYN;ADRA2B GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0016032| viral reproduction SRC;HCK;LYN;HTR2A GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K1;MAP2K2 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;SRC;ABL1 GO:0042493| response to drug DRD3;LYN;HTR2A;DRD1;HTR2C;HTR2B;SRC;DRD2;HTR1B;ABCB1 GO:0035556| intracellular signal transduction SRC;DRD2;BCR;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process HTR2B;HCK;SRC GO:0008284| positive regulation of cell proliferation HTR2B;ADRA2A;HCK;HTR1A;HTR2A;CDK2;LYN;DRD3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0007507| heart development HTR2B;MAP2K1 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;SRC;ADRA2A GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0048678| response to axon injury LYN;DRD2 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 3505:[DB06616 DB03685] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways GO:0050900| leukocyte migration B4GALT1;LYN;SRC GO:0016032| viral reproduction LYN;UCKL1;HCK;SRC GO:0042127| regulation of cell proliferation B4GALT1;ABL1;SRC GO:0043065| positive regulation of apoptotic process B4GALT1;ABL1;SRC GO:0009615| response to virus ISG20;SRC GO:0045087| innate immune response ISG20;ABL1;HCK;SRC;LYN GO:0007155| cell adhesion HCK;SRC;ABL1;B4GALT1 GO:0008283| cell proliferation SRC;ISG20 GO:0008285| negative regulation of cell proliferation B4GALT1;LYN;MAP2K1 GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;UCKL1;MAP2K1;SRC;MAP2K2;BCR GO:0002376| immune system process ISG20;SRC;HCK;LYN 3506:[DB06616 DB07926] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07926|N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE MMP1 common genes common pathways GO:0050900| leukocyte migration LYN;SRC;MMP1 GO:0016032| viral reproduction HCK;SRC;MMP1;LYN 3507:[DB06616 DB07218] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07218|6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE MAPK8IP1;MAPK8 common genes common pathways GO:0038095| LYN;MAPK8 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;MAPK8;CAMK2G GO:0034614| cellular response to reactive oxygen species MAPK8;SRC GO:0010628| positive regulation of gene expression MAPK8;MAP2K1;SRC GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAPK8;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;MAP2K1;MAPK8;HCK;BCR;MAP2K2;SRC GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;MAPK8IP1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity MAPK8;HCK GO:0006355| regulation of transcription, DNA-dependent MAPK8IP1;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MAPK8IP1;SRC GO:0018105| peptidyl-serine phosphorylation SRC;MAPK8;CAMK2G;CDK2 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;MAPK8;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;MAPK8;SRC GO:0043066| negative regulation of apoptotic process MAPK8IP1;MAPK8;HCK;SRC GO:0071260| cellular response to mechanical stimulus MAPK8;MAP3K2 3508:[DB06616 DB01179] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;TOP2A GO:0002576| platelet degranulation LYN;TUBA4A GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB;CDK2;TUBA4A GO:0051301| cell division CDK2;TUBB GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBA4A;TUBB;CDK2 GO:0006928| cellular component movement TUBB;MAP2K1 3509:[DB06616 DB05127] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05127|ANA971 TLR7 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;TLR7;LYN GO:0002376| immune system process SRC;HCK;LYN;TLR7 GO:0071260| cellular response to mechanical stimulus MAP3K2;TLR7 GO:0045087| innate immune response HCK;SRC;ABL1;LYN;TLR7 GO:0001932| regulation of protein phosphorylation MAP2K1;TLR7;LYN GO:0006954| inflammatory response HCK;LYN;TLR7 3510:[DB06616 DB03372] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways GO:0001933| negative regulation of protein phosphorylation IL2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL2;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;IL2;HCK GO:0043066| negative regulation of apoptotic process SRC;HCK;IL2 GO:0007155| cell adhesion HCK;SRC;IL2;ABL1 GO:0001934| positive regulation of protein phosphorylation IL2;ABL1;LYN GO:0050728| negative regulation of inflammatory response IL2;BCR GO:0002250| adaptive immune response LYN;IL2 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;IL2;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;IL2 GO:0002376| immune system process LYN;IL2;SRC;HCK GO:0065009| regulation of molecular function IL2;CAMK2G 3511:[DB06616 DB02059] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02059|Adenosine-5-Diphosphoribose EEF2;GAPDH;SIRT5;SIRT3 common genes common pathways GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;SIRT3;LYN GO:2000378| negative regulation of reactive oxygen species metabolic process SIRT3;BCR;SIRT5 GO:0006915| apoptotic process ABL1;GAPDH GO:0050715| positive regulation of cytokine secretion SRC;GAPDH GO:0031667| response to nutrient levels SRC;SIRT5 GO:0042493| response to drug LYN;EEF2;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;GAPDH;CYP2C8 GO:0042542| response to hydrogen peroxide SRC;EEF2 3512:[DB06616 DB01148] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways GO:0007399| nervous system development CAMK2G;CHRM1;CHRM2 GO:0009615| response to virus SRC;CHRM2 GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0007165| signal transduction SRC;BCR;MAP2K1;CHRM1;CHRM2;LYN GO:0006464| protein modification process ABL1;CHRM1 GO:0008283| cell proliferation SRC;CHRM1 3513:[DB06616 DB01594] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0006810| transport ABCB1;GABRB3;GABRA3;GABRG2;GABRB1;GABRA5;GABRR2;GABRA1;GABRD;GABRB2;GABRR1 GO:0007165| signal transduction GABRE;GABRR2;GABRA5;GABRB1;GABRD;GABRP;LYN;BCR;SRC;MAP2K1;GABRB3 GO:0007420| brain development BCR;GABRA5 GO:0009636| response to toxin GABRB1;LYN GO:0009791| post-embryonic development ABL1;GABRG2 GO:0042493| response to drug ABCB1;SRC;GABRG3;LYN 3514:[DB06616 DB00645] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00645|Dyclonine SCN10A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN10A 3515:[DB06616 DB09213] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09213|Dexibuprofen PTGS2;PTGS1;BCL2;THBD;PLAT;FABP2;PPARG;CFTR;SLC15A1;PPARA;GP1BA;S100A7;CYP2C9;UGT1A1;UGT1A3;UGT1A9;UGT2B4;UGT2B7;CYP2C8;CYP2C19;AMACR;ALB;ABCC4;ABCC1;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLCO2B1;ABCB1 common genes CYP2C8;ABCB1 common pathways GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process PTGS1;UGT2B7;PTGS2;CYP2C9;PPARG;PPARA;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006974| response to DNA damage stimulus ABL1;BCL2;LYN;CDK2 GO:0007155| cell adhesion SRC;GP1BA;HCK;ABL1 GO:0045087| innate immune response SRC;HCK;ABL1;PPARG;LYN;S100A7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;CDK2 GO:0007507| heart development MAP2K1;PPARA;PPARG GO:0042981| regulation of apoptotic process BCL2;MAP3K2;MAP2K1;MAP2K2 GO:0006082| organic acid metabolic process CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C9;UGT2B4;CYP3A4;UGT1A9;CYP2C8;CYP2C19;PTGS1 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;BCL2;SRC;HCK;ALB GO:0043065| positive regulation of apoptotic process PPARG;PTGS2;ABL1;SRC GO:0002576| platelet degranulation ALB;ABCC4;LYN GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0008284| positive regulation of cell proliferation HCK;BCL2;PTGS2;CDK2;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;BCL2 GO:0051726| regulation of cell cycle BCL2;ABL1;SRC;BCR GO:0042542| response to hydrogen peroxide SRC;BCL2 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;PLAT;BCR;SRC GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide THBD;S100A7;PTGS2;UGT1A1;BCR GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0001782| B cell homeostasis BCL2;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway BCL2;SRC GO:0019221| cytokine-mediated signaling pathway HCK;GP1BA GO:0051924| regulation of calcium ion transport CAMK2G;BCL2 GO:2000811| negative regulation of anoikis SRC;BCL2 GO:0006954| inflammatory response PTGS2;LYN;HCK;PTGS1 GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C9;CYP3A4;ABCC4;PTGS1;CYP2C19;CYP2C8 GO:0099040| ABCB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0050900| leukocyte migration THBD;LYN;SRC GO:0010506| regulation of autophagy BCL2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;PPARA;PPARG;CDK2;MAP3K2 GO:0042493| response to drug ABCC4;ABCB1;SRC;ABCC1;BCL2;PTGS2;UGT1A1;LYN;PPARG GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP2C9;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA;ABL1 GO:0051902| negative regulation of mitochondrial depolarization SRC;BCL2 GO:0030097| hemopoiesis LYN;BCL2 GO:0070542| response to fatty acid PTGS2;SRC GO:0003014| renal system process BCL2;BCR GO:0007165| signal transduction LYN;THBD;PPARG;MAP2K1;BCR;SRC GO:0097267| CYP2C8;CYP2C19;CYP2C9 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2C9;CYP3A4;UGT1A3;CYP2C8;CYP2C19 GO:0006979| response to oxidative stress ABL1;PTGS1;BCL2;PTGS2 GO:0048536| spleen development BCL2;ABL1 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0048538| thymus development BCL2;MAP2K1;ABL1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0030168| platelet activation GP1BA;SRC;LYN GO:0006810| transport ABCB1;SLC15A1;ABCC1 GO:0045930| negative regulation of mitotic cell cycle ABL1;BCL2 GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0071456| cellular response to hypoxia SRC;BCL2;PTGS2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0098609| SRC;BCL2 GO:0008202| steroid metabolic process UGT2B7;CYP2C8;CYP2C19;UGT1A1;CYP2C9;CYP3A4 GO:0034605| cellular response to heat LYN;PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;BCL2;PPARG;LYN GO:0010033| response to organic substance PPARG;CDK2;PTGS2;UGT1A1;ABCC4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0006464| protein modification process PLAT;ABL1 GO:0014911| positive regulation of smooth muscle cell migration SRC;BCL2 GO:0030336| negative regulation of cell migration BCL2;BCR GO:0009791| post-embryonic development BCL2;ABL1 GO:0050853| B cell receptor signaling pathway LYN;BCL2;ABL1 GO:0006915| apoptotic process ABL1;BCL2 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0032868| response to insulin stimulus PPARA;LYN GO:0042100| B cell proliferation BCL2;ABL1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;BCL2;CAMK2G GO:0055085| transmembrane transport SLC22A11;SLCO2B1;ABCC4;ABCB1;SLC22A8;SLC15A1;ABCC1;SLCO1A2;BCL2;CFTR;SLC22A6 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;S100A7 GO:0006470| protein dephosphorylation CAMK2G;BCL2 GO:0002933| CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound LYN;PPARG;PTGS2;UGT1A1;ABCC4 GO:0009636| response to toxin SLC22A8;LYN;BCL2 GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;BCL2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis BCL2;ABL1 GO:0030216| keratinocyte differentiation S100A7;MAP2K1 GO:0007596| blood coagulation THBD;LYN;GP1BA;PLAT GO:0008283| cell proliferation SRC;BCL2 3516:[DB06616 DB06725] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways GO:0006979| response to oxidative stress ABL1;PTGS1;PTGS2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0070542| response to fatty acid PTGS2;SRC GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C9;CYP2C8 GO:0034605| cellular response to heat LYN;PTGS2 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;PTGS1;CYP2C8 GO:0008284| positive regulation of cell proliferation PTGS2;LYN;CDK2;HCK GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9;PTGS1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006954| inflammatory response PTGS1;HCK;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2C9 GO:0042493| response to drug PTGS2;LYN;SRC;ABCB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;PTGS2;CYP2C8;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC 3517:[DB06616 DB04863] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0007155| cell adhesion ABL1;HCK;ITGB3;SRC;ITGA2B GO:0045124| regulation of bone resorption SRC;ITGB3 GO:0002576| platelet degranulation ITGA2B;LYN;ITGB3 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ITGB3;SRC;ABL1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC;ITGB3 GO:0016032| viral reproduction LYN;SRC;ITGB3;HCK GO:0050900| leukocyte migration LYN;SRC;ITGB3 GO:0001934| positive regulation of protein phosphorylation ITGB3;ABL1;LYN GO:0007229| integrin-mediated signaling pathway SRC;ITGB3;HCK;ABL1;ITGA2B GO:0030168| platelet activation LYN;ITGB3;SRC GO:0010595| positive regulation of endothelial cell migration ITGB3;ABL1 GO:0007596| blood coagulation ITGB3;LYN 3518:[DB06616 DB01580] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction SRC;ADRB1;BCR;MAP2K1;ADRB3;ADRB2;LYN GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 3519:[DB06616 DB00725] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways GO:0007399| nervous system development CHRM2;CHRM1;CAMK2G;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;LYN;CDK2;HCK GO:0009615| response to virus CHRM2;SRC GO:0008283| cell proliferation SRC;CHRM4;CHRM5;CHRM3;CHRM1 GO:0006464| protein modification process CHRM3;CHRM1;ABL1 GO:0007165| signal transduction CHRM1;CHRM2;LYN;CHRM5;CHRM3;SRC;BCR;CHRM4;MAP2K1 3520:[DB06616 DB00838] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00838|Clocortolone NR3C1 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;NR3C1;LYN GO:0007049| cell cycle NR3C1;CDK2;SRC GO:0006915| apoptotic process ABL1;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0051301| cell division CDK2;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 3521:[DB06616 DB06935] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR 3522:[DB06616 DB01833] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01833|L-2-Amino-4-(Guanidinooxy)Butyric Acid NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN GO:0043542| endothelial cell migration NOS3;ABL1 GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 GO:0008285| negative regulation of cell proliferation MAP2K1;NOS3;LYN 3523:[DB06616 DB08128] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08128|(1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine PNMT common genes common pathways 3524:[DB06616 DB03439] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03439|4,6-dideoxy-4-amino-alpha-D-glucose AMY1A;AMY2A;AMY2A common genes common pathways 3525:[DB06616 DB06981] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06981|(2S)-2-(1H-indol-3-yl)pentanoic acid SKP1 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway SKP1;SRC;LYN GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1;SKP1 GO:0038095| LYN;SKP1 3526:[DB06616 DB01415] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC15A1;SLC15A2;SLC22A8;SLC22A6;ABCB1 GO:0009636| response to toxin LYN;SLC22A8 GO:0006810| transport SLC15A1;SLC15A2;ABCB1 3527:[DB06616 DB06803] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP1A2;CYP2C9;CYP3A4;CYP2C8 GO:0042493| response to drug LYN;CYP1A2;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2C9 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2C9;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 3528:[DB06616 DB06914] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0034605| cellular response to heat LYN;HMOX1 GO:0071456| cellular response to hypoxia SRC;HMOX1 GO:0006979| response to oxidative stress ABL1;HMOX1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;HMOX1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;HMOX1 GO:0006915| apoptotic process HMOX1;ABL1 GO:0008285| negative regulation of cell proliferation MAP2K1;HMOX1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;ABL1 GO:0042542| response to hydrogen peroxide SRC;HMOX1 GO:0043065| positive regulation of apoptotic process HMOX1;SRC;ABL1 GO:0035556| intracellular signal transduction CAMK2G;HMOX1;LYN;SRC;BCR GO:0055114| oxidation-reduction process HMOX1;CYP3A4;CYP2C8 3529:[DB06616 DB03937] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03937|Erythose-4-Phosphate kdsA;GPI common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;SRC 3530:[DB06616 DB00175] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes ABCB1;CYP2C8 common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042493| response to drug LYN;SRC;ABCB1;ABCG2;ABCC2 GO:0050900| leukocyte migration SRC;SLC16A1;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HMGCR GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0071222| cellular response to lipopolysaccharide ABCC2;ABL1;SRC;BCR GO:0008284| positive regulation of cell proliferation HMGCR;CDK2;LYN;HCK GO:0043066| negative regulation of apoptotic process SRC;HCK;HMGCR GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0006082| organic acid metabolic process CYP2C8 GO:0006629| lipid metabolic process SLC16A1;CYP3A4;HMGCR GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:0043407| negative regulation of MAP kinase activity LYN;HMGCR GO:0009636| response to toxin LYN;SLC22A8 GO:0002933| CYP3A4;CYP2C8 GO:0055085| transmembrane transport ABCB1;SLC16A1;ABCG2;SLC22A7;SLC22A11;ABCC2;SLCO2B1;SLC22A6;SLCO1A2;SLCO1B3;ABCB11;SLC22A8;SLCO1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;HMGCR GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0006979| response to oxidative stress ABCC2;ABL1 GO:0097267| CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;HMGCR GO:0045332| phospholipid translocation ABCB1 GO:0006810| transport ABCB1;ABCG2;ABCC2;ABCB11 GO:0042908| xenobiotic transport ABCG2;ABCB1 3531:[DB06616 DB01837] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01837|O-acetyl-L-serine PTGS1 common genes common pathways GO:0006954| inflammatory response LYN;PTGS1;HCK GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1 GO:0006979| response to oxidative stress PTGS1;ABL1 3532:[DB06616 DB05943] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05943|Resatorvid CSF2RB;IL2RG common genes common pathways GO:0016032| viral reproduction LYN;IL2RG;HCK;SRC GO:0000165| MAPKKK cascade IL2RG;CAMK2G;CSF2RB;MAP2K1;MAP2K2 GO:0019221| cytokine-mediated signaling pathway HCK;CSF2RB GO:0032496| response to lipopolysaccharide BCR;CSF2RB GO:0018108| peptidyl-tyrosine phosphorylation CSF2RB;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0065009| regulation of molecular function CAMK2G;CSF2RB;IL2RG GO:0007165| signal transduction IL2RG;CSF2RB;LYN;BCR;SRC;MAP2K1 3533:[DB06616 DB09422] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09422|Soybean oil PPARA common genes common pathways GO:0050728| negative regulation of inflammatory response PPARA;BCR GO:0006355| regulation of transcription, DNA-dependent PPARA;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;PPARA;CDK2;MAP2K2;SRC;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARA GO:0007507| heart development PPARA;MAP2K1 GO:0006629| lipid metabolic process PPARA;CYP3A4 GO:0032868| response to insulin stimulus LYN;PPARA 3534:[DB06616 DB03245] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;GCDH 3535:[DB06616 DB00816] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00816|Orciprenaline ADRB2 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0007165| signal transduction LYN;ADRB2;MAP2K1;BCR;SRC GO:0045453| bone resorption SRC;ADRB2 3536:[DB06616 DB01983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01983|2(S)-Amino-6-Boronohexanoic Acid ARG1 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;ARG1 GO:0048678| response to axon injury ARG1;LYN GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ARG1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;SRC GO:0045087| innate immune response LYN;HCK;SRC;ABL1;ARG1 GO:0042493| response to drug LYN;ARG1;ABCB1;SRC GO:0002250| adaptive immune response ARG1;LYN GO:0043434| response to peptide hormone stimulus LYN;ARG1 GO:0002376| immune system process ARG1;SRC;HCK;LYN GO:0043200| response to amino acid stimulus ARG1;LYN GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 3537:[DB06616 DB02548] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02548|D-glucitol 6-phosphate GPI common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;SRC 3538:[DB06616 DB04185] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04185|Norvaline OTC;GATM common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;GATM GO:0031667| response to nutrient levels OTC;SRC GO:0042493| response to drug LYN;OTC;SRC;ABCB1 GO:0032868| response to insulin stimulus OTC;LYN 3539:[DB06616 DB08962] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08962|Glibornuride CYP2C9 common genes common pathways GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 3540:[DB06616 DB03903] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03903|Tmr ACTA1 common genes common pathways GO:0010628| positive regulation of gene expression SRC;ACTA1;MAP2K1 GO:0009612| response to mechanical stimulus SRC;ACTA1 3541:[DB06616 DB00936] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2;SLC16A1;PTGS1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;AKR1C1;CYP2C8;PTGS1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;PTGS1;SRC GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0050900| leukocyte migration SLC16A1;SRC;LYN GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;AKR1C1;CYP2C9;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0042493| response to drug PTGS2;LYN;SRC;ABCB1 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0070542| response to fatty acid PTGS2;SRC GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0055085| transmembrane transport SLC22A6;SLC22A10;SLC22A8;ABCB1;SLC22A7;SLC16A1;SLCO2B1;SLC22A11 GO:0009636| response to toxin LYN;SLC22A8 GO:0014070| response to organic cyclic compound LYN;PTGS2 3542:[DB06616 DB01165] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006810| transport ABCC2;ABCB1;ABCB11;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0006855| drug transmembrane transport ABCC1;SLC22A5;ABCB1;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCC2;SLC22A6;ABCC1;SLC22A4;SLC22A5;ABCB11 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006974| response to DNA damage stimulus ABL1;TOP2A;LYN;CDK2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;ABCC2;SRC;BCR GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;ABCC2;BCR GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCC2;ABCB1;SRC;LYN;CYP1A2;ABCC1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 3543:[DB06616 DB00671] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport ABCB1;SLC15A2;SLC15A1 GO:0055085| transmembrane transport SLC15A1;SLC22A5;SLC15A2;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 3544:[DB06616 DB05801] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05801|GTI 2040 RRM2 common genes common pathways GO:0055114| oxidation-reduction process RRM2;CYP2C8;CYP3A4 GO:0006260| DNA replication RRM2;CDK2 3545:[DB06616 DB01959] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways GO:0007165| signal transduction LYN;PDE4D;PDE4B;MAP2K1;BCR;SRC GO:0050900| leukocyte migration LYN;PDE4D;PDE4B;SRC GO:0071222| cellular response to lipopolysaccharide PDE4D;ABL1;PDE4B;SRC;BCR 3546:[DB06616 DB01618] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0048678| response to axon injury DRD2;LYN GO:0007399| nervous system development CAMK2G;CHRM1 GO:0035556| intracellular signal transduction DRD2;SRC;BCR;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HTR1A;CHRM1;HCK GO:0042493| response to drug SRC;DRD2;ABCB1;LYN;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0016032| viral reproduction HCK;SRC;LYN;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0030900| forebrain development SRC;DRD2 GO:0007165| signal transduction LYN;HTR2A;HTR1A;CHRM1;MAP2K1;BCR;DRD2;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K2;DRD2;SRC;MAP2K1;ABL1 GO:0009636| response to toxin DRD2;LYN GO:0008283| cell proliferation SRC;CHRM1;HTR1A GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0006464| protein modification process CHRM1;ABL1 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0030336| negative regulation of cell migration BCR;DRD2 3547:[DB06616 DB08894] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08894|Peginesatide EPOR common genes common pathways GO:0019221| cytokine-mediated signaling pathway EPOR;HCK GO:0007507| heart development MAP2K1;EPOR GO:0007165| signal transduction SRC;BCR;MAP2K1;EPOR;LYN GO:0007420| brain development EPOR;BCR 3548:[DB06616 DB07546] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways GO:0007049| cell cycle SRC;CSNK2A2;CDK2 GO:0006915| apoptotic process CSNK2A2;ABL1 GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;MAP3K2;CSNK2A2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0016310| phosphorylation LYN;CDK2;CAMK2G;CSNK2A2;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent CSNK2A2;ABL1 GO:0016236| macroautophagy CSNK2A2;SRC GO:0051726| regulation of cell cycle CSNK2A2;ABL1;BCR;SRC GO:1901796| CSNK2A2;CDK2 3549:[DB06616 DB05111] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05111|Fontolizumab IFNG common genes common pathways GO:0002250| adaptive immune response LYN;IFNG GO:0010629| negative regulation of gene expression IFNG;MAP2K1;MAP2K2 GO:0001934| positive regulation of protein phosphorylation ABL1;IFNG;LYN GO:0008284| positive regulation of cell proliferation HCK;IFNG;CDK2;LYN GO:0009615| response to virus SRC;IFNG GO:0010634| positive regulation of epithelial cell migration SRC;IFNG GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;IFNG GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IFNG GO:0071902| positive regulation of protein serine/threonine kinase activity IFNG;MAP2K2;SRC;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;IFNG GO:0006928| cellular component movement IFNG;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;IFNG GO:0006915| apoptotic process IFNG;ABL1 GO:0060333| interferon-gamma-mediated signaling pathway HCK;IFNG;CAMK2G GO:0007050| cell cycle arrest IFNG;ABL1;MAP2K1 3550:[DB06616 DB03600] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FURIN GO:0008283| cell proliferation SRC;FURIN GO:0014070| response to organic cyclic compound LYN;PPARG GO:0007165| signal transduction LYN;PPARG;MAP2K1;BCR;SRC GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug LYN;PPARG;SRC;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;PPARG;MAP2K1;SRC;MAP2K2 GO:0007507| heart development PPARG;MAP2K1 GO:0045087| innate immune response ABL1;SRC;HCK;PPARG;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;SRC;ABL1 GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0009612| response to mechanical stimulus PPARG;SRC GO:0071300| cellular response to retinoic acid LYN;PPARG 3551:[DB06616 DB01436] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0036378| CYP3A4;CYP27B1 GO:0010628| positive regulation of gene expression VDR;MAP2K1;SRC GO:0042359| vitamin D metabolic process CYP3A4;CYP27B1;GC GO:0008285| negative regulation of cell proliferation MAP2K1;VDR;LYN;CYP27B1 GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC GO:0007165| signal transduction MAP2K1;VDR;SRC;BCR;LYN GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent RXRA;VDR;ABL1 GO:0055114| oxidation-reduction process CYP3A4;CYP27B1;CYP2C8 GO:0016032| viral reproduction LYN;RXRA;HCK;SRC GO:0006816| calcium ion transport VDR;CAMK2G;CYP27B1 GO:0032496| response to lipopolysaccharide CYP27B1;BCR GO:0007275| multicellular organismal development CDK2;CAMK2G;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;CDK2;VDR GO:0007507| heart development MAP2K1;RXRA 3552:[DB06616 DB00866] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;HTR1A;LYN;CDK2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K2;SRC;MAP2K1 GO:0008283| cell proliferation SRC;HTR1A GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction ADRB3;MAP2K1;BCR;SRC;ADRB1;LYN;ADRB2;HTR1A GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 3553:[DB06616 DB09069] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09069|Trimetazidine ACAA1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ACAA1 3554:[DB06616 DB08256] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2;CYP2C8 GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0006954| inflammatory response EPHX2;LYN;HCK GO:0017144| drug metabolic process CYP2C8;EPHX2;CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;SRC;EPHX2 GO:0009636| response to toxin EPHX2;LYN 3555:[DB06616 DB02563] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02563|Hexanoyl-CoA ECHS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ECHS1 3556:[DB06616 DB07830] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0008284| positive regulation of cell proliferation CDK2;LYN;DPP4;HCK GO:0031295| T cell costimulation SRC;DPP4;LYN 3557:[DB06616 DB11785] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11785|Anisodamine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 3558:[DB06616 DB12450] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12450|Propyl Gallate ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;ESR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;ESR1;CDK2;MAP3K2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0060065| uterus development SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 3559:[DB06616 DB07233] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07233|N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan ADAM17 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;ADAM17;CDK2;LYN GO:0051272| positive regulation of cellular component movement LYN;ADAM17 GO:0007155| cell adhesion ADAM17;SRC;HCK;ABL1 GO:0032496| response to lipopolysaccharide BCR;ADAM17 GO:0048870| cell motility ADAM17;MAP2K1 GO:0042493| response to drug LYN;ADAM17;ABCB1;SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;ADAM17 GO:0001934| positive regulation of protein phosphorylation LYN;ADAM17;ABL1 GO:0048536| spleen development ADAM17;ABL1 GO:0030335| positive regulation of cell migration LYN;ADAM17 3560:[DB06616 DB08936] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08936|Chlorcyclizine HRH1 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;HRH1;LYN GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0006954| inflammatory response HRH1;LYN;HCK 3561:[DB06616 DB04608] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04608|9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE WEE1 common genes common pathways GO:0016310| phosphorylation WEE1;CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;WEE1;CDK2;LYN GO:0007049| cell cycle SRC;CDK2;WEE1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;WEE1;CDK2 GO:0051726| regulation of cell cycle WEE1;BCR;SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;WEE1;LYN GO:0051301| cell division CDK2;WEE1 GO:0000082| G1/S transition of mitotic cell cycle CAMK2G;CDK2;WEE1 GO:0000278| mitotic cell cycle WEE1;ABL1 3562:[DB06616 DB09160] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug SRC;ABCB1;LYN GO:1901529| ABCB1 3563:[DB06616 DB12872] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;COL1A1 GO:0071300| cellular response to retinoic acid LYN;COL1A1 GO:0071560| cellular response to transforming growth factor beta stimulus COL1A1;SRC GO:0009612| response to mechanical stimulus SRC;COL1A1 GO:0002576| platelet degranulation F8;LYN GO:0042542| response to hydrogen peroxide COL1A1;SRC GO:0071222| cellular response to lipopolysaccharide ABL1;ADAMTS13;SRC;BCR GO:0055114| oxidation-reduction process CYP3A4;F8;CYP2C8 GO:0050900| leukocyte migration COL1A1;SRC;LYN GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;SRC;COL1A1;MAP2K2 GO:0031667| response to nutrient levels SRC;COL1A1 GO:0042493| response to drug SRC;ABCB1;COL1A1;LYN GO:0030168| platelet activation LYN;F8;SRC;COL1A1;ADAMTS13 GO:0007229| integrin-mediated signaling pathway ADAMTS13;HCK;SRC;ABL1 GO:0030335| positive regulation of cell migration LYN;COL1A1 GO:0043434| response to peptide hormone stimulus COL1A1;LYN GO:0009636| response to toxin ADAMTS13;LYN GO:0007596| blood coagulation ADAMTS13;COL1A1;F8;LYN GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;COL1A1 3564:[DB06616 DB00135] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0043434| response to peptide hormone stimulus TH;LYN GO:0006810| transport ABCB1;SLC16A2 GO:0006979| response to oxidative stress ABL1;TAT GO:0007165| signal transduction MAP2K1;YARS;BCR;SRC;LYN GO:0014070| response to organic cyclic compound TH;TAT;LYN GO:0006915| apoptotic process ABL1;YARS GO:0055085| transmembrane transport SLC16A2;ABCB1;SLC16A10 GO:0032496| response to lipopolysaccharide BCR;TH GO:0007507| heart development TH;MAP2K1 GO:0031667| response to nutrient levels TH;SRC GO:0042493| response to drug ABCB1;SRC;TH;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;TH GO:0051602| response to electrical stimulus TH;SRC 3565:[DB06616 DB02340] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02340|N-Acetyl-Serine F13A1 common genes common pathways GO:0007596| blood coagulation LYN;F13A1 GO:0002576| platelet degranulation LYN;F13A1 3566:[DB06616 DB06477] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways GO:0042493| response to drug LYN;DRD3;ABCB1;DRD2;SRC GO:0048678| response to axon injury DRD2;LYN GO:0035556| intracellular signal transduction BCR;DRD2;SRC;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DRD3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0009636| response to toxin DRD2;LYN GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;DRD4;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;DRD2 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;LYN GO:0030900| forebrain development SRC;DRD2 GO:0007165| signal transduction MAP2K1;SRC;DRD2;BCR;DRD3;LYN;DRD4 3567:[DB06616 DB02483] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0014070| response to organic cyclic compound LYN;LDHA GO:0007165| signal transduction MAP2K1;BST1;BCR;SRC;LYN GO:0032956| regulation of actin cytoskeleton organization BST1;ABL1 GO:0055114| oxidation-reduction process CYP2C8;LDHA;CYP3A4 GO:0042493| response to drug LDHA;LYN;ABCB1;SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1;LDHA GO:0050727| regulation of inflammatory response LYN;BST1;HCK GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;BST1 GO:0042542| response to hydrogen peroxide LDHA;SRC 3568:[DB06616 DB07092] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion HCK;SRC;ABL1;DPP4 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;DPP4 GO:0031295| T cell costimulation LYN;DPP4;SRC 3569:[DB06616 DB00654] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGFR;HCK GO:0043066| negative regulation of apoptotic process SRC;PTGFR;HCK GO:0032496| response to lipopolysaccharide PTGFR;BCR GO:0007165| signal transduction SRC;PTGFR;BCR;MAP2K1;LYN GO:0010628| positive regulation of gene expression MAP2K1;PTGFR;SRC GO:0055085| transmembrane transport SLCO2B1;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport ABCB1;SLC22A1 3570:[DB06616 DB07907] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07907|(2S)-2-HYDROXYOCTANOIC ACID HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HAO1;CYP2C8 GO:0006979| response to oxidative stress HAO1;ABL1 3571:[DB06616 DB04363] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways GO:0055114| oxidation-reduction process BLVRB;CYP3A4;CYP2C8 3572:[DB06616 DB07255] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07255|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3-MORPHOLIN-4-YLPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2;EPHB4 GO:0016310| phosphorylation MAP3K2;CAMK2G;EPHB4;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;EPHB4;HCK GO:0048013| ephrin receptor signaling pathway EPHB4;LYN;SRC GO:0046777| protein autophosphorylation CAMK2G;EPHB4;LYN;SRC;BCR;HCK;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;LYN;EPHB4 GO:0007275| multicellular organismal development CDK2;EPHB4;CAMK2G GO:0007155| cell adhesion EPHB4;ABL1;SRC;HCK 3573:[DB06616 DB00292] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;SLC2A1 GO:0006629| lipid metabolic process CYP3A4;CYP11B2;CYP11B1 GO:0032148| activation of protein kinase B activity SRC;ADRA2B GO:0060065| uterus development CYP19A1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP11B1;CYP11B2;CYP19A1;CYP3A4 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1;GABRG3 GO:0030168| platelet activation LYN;ADRA2B;SRC GO:0006810| transport GABRB3;ABCB1;GABRA1;GABRD;GABRB2;GABRA4;GABRA6;GABRA3;GABRA5;GABRG2;GABRB1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP11B1;CYP11B2;CYP2C8 GO:0007417| central nervous system development SRC;LYN;GABRA4 GO:0007420| brain development GABRA5;BCR GO:0007165| signal transduction GABRB3;BCR;SRC;MAP2K1;GABRA6;GABRD;LYN;GABRP;ADRA2B;GABRE;GABRB1;GABRA5;GABRQ GO:0000187| activation of MAPK activity MAP3K2;ADRA2B;MAP2K2;MAP2K1 GO:0055085| transmembrane transport SLC2A1;ABCB1 GO:0032868| response to insulin stimulus LYN;SLC2A1 GO:0009636| response to toxin GABRB1;LYN GO:0009791| post-embryonic development ABL1;GABRG2 3574:[DB06616 DB00263] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00263|Sulfisoxazole CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 3575:[DB06616 DB07458] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07458|3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione PRKACA common genes common pathways GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;PRKACA GO:0043393| regulation of protein binding PRKACA;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway PRKACA;LYN;SRC GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2 GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;PRKACA;LYN;CDK2 GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;PRKACA;CAMK2G GO:0034605| cellular response to heat PRKACA;LYN GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;PRKACA GO:0007596| blood coagulation PRKACA;LYN 3576:[DB06616 DB02857] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02857|Guanosine PNP common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;PNP 3577:[DB06616 DB06660] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06660|Saredutant TACR2 common genes common pathways GO:0051602| response to electrical stimulus TACR2;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;TACR2 3578:[DB06616 DB07129] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07129|(2R)-1-(2,6-dimethylphenoxy)propan-2-amine PLAU common genes common pathways GO:0030335| positive regulation of cell migration LYN;PLAU GO:0007165| signal transduction PLAU;MAP2K1;SRC;BCR;LYN GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007596| blood coagulation PLAU;LYN GO:0042127| regulation of cell proliferation SRC;PLAU;ABL1 GO:0006935| chemotaxis MAP2K1;PLAU 3579:[DB06616 DB12836] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes ABCB1 common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGER4 GO:0009612| response to mechanical stimulus PTGER4;SRC GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation LYN;ALB GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide BCR;PTGER4 GO:0050728| negative regulation of inflammatory response PTGER4;BCR GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;PTGER4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug SRC;ABCB1;LYN GO:0007165| signal transduction LYN;PTGER4;MAP2K1;SRC;BCR GO:0050715| positive regulation of cytokine secretion SRC;PTGER4 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 3580:[DB06616 DB06281] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06281|Torcetrapib CETP;CYP11B2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP11B2;CYP2C8 GO:0006629| lipid metabolic process CETP;CYP11B2;CYP3A4 GO:0008202| steroid metabolic process CETP;CYP2C8;CYP3A4;CYP11B2 3581:[DB06616 DB03064] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03064|3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;ABL1 GO:0055114| oxidation-reduction process HAO1;CYP3A4;CYP2C8 3582:[DB06616 DB00139] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC13A1;ABCB1;SLC22A8;SLC13A3;SLC13A2 GO:0009636| response to toxin SLC22A8;LYN GO:0006464| protein modification process PLOD1;ABL1 GO:0008285| negative regulation of cell proliferation ASPH;P3H1;MAP2K1;P3H2;LYN;P3H3 GO:0009791| post-embryonic development ABL1;ALDH5A1 GO:0006810| transport ABCB1;SLC13A2 GO:0007417| central nervous system development SRC;ALDH5A1;LYN GO:0008202| steroid metabolic process HSD17B6;CYP2C8;CYP3A4 GO:0009725| response to hormone stimulus OXCT1;LYN GO:0007420| brain development BCR;OXCT1 GO:0007165| signal transduction SRC;BCR;SUCNR1;MAP2K1;LYN GO:0055114| oxidation-reduction process PLOD3;BBOX1;CYP2C8;SDHB;P3H1;ALDH5A1;P4HA1;HSD17B6;ASPH;P3H3;SDHC;SDHA;SDHD;CYP3A4;TMLHE;P4HA2;P3H2;PLOD1 GO:0060425| lung morphogenesis MAP2K1;PLOD3 GO:0042493| response to drug ABCB1;SRC;OXCT1;LYN GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;SRC;MAP2K2;ASPH GO:0007399| nervous system development SDHA;CAMK2G GO:0007507| heart development OXCT1;MAP2K1 GO:0006629| lipid metabolic process HSD17B6;CYP3A4 3583:[DB06616 DB02110] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0034599| cellular response to oxidative stress ABL1;CYCS GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC GO:0006954| inflammatory response HCK;PTGS1;LYN GO:0055114| oxidation-reduction process CYP3A4;CYCS;CYP2C8;PTGS1 GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0006915| apoptotic process CYCS;ABL1 GO:0006470| protein dephosphorylation CYCS;CAMK2G 3584:[DB06616 DB01854] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01854|5-Bromonicotinamide ART1 common genes common pathways 3585:[DB06616 DB06156] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SRC;ABCB1;SLC6A3;SLC6A4;SLC6A2;LYN GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0009636| response to toxin LYN;SLC6A4 GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0055085| transmembrane transport SLC6A2;SLC6A4;SLC6A3;ABCB1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;SLC6A4 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 GO:0007420| brain development BCR;SLC6A4 3586:[DB06616 DB09016] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09016|Butriptyline SLC6A4;HRH1;HTR2A common genes common pathways GO:0007165| signal transduction HTR2A;LYN;HRH1;SRC;BCR;MAP2K1 GO:0007420| brain development SLC6A4;BCR GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K2;SRC;MAP2K1;ABL1 GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0009636| response to toxin SLC6A4;LYN GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0008284| positive regulation of cell proliferation HTR2A;CDK2;LYN;HCK GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;HTR2A GO:0016032| viral reproduction HCK;SRC;HTR2A;LYN GO:0006954| inflammatory response HRH1;LYN;HCK GO:0043114| regulation of vascular permeability HRH1;SRC;BCR GO:0042493| response to drug HTR2A;LYN;ABCB1;SRC;SLC6A4 3587:[DB06616 DB01430] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0006813| potassium ion transport CDK2;ATP1A1 GO:0042493| response to drug ABCB1;SRC;ATP1A1;LYN GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 3588:[DB06616 DB04234] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04234|N2-({[(4-Bromophenyl)Methyl]Oxy}Carbonyl)-N1-[(1s)-1-Formylpentyl]-L-Leucinamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 3589:[DB06616 DB06701] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A3;SLC6A4;ABCB1;SRC;LYN;SLC6A2 GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0009636| response to toxin LYN;SLC6A4 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A3;SLC6A2 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0010033| response to organic substance SLC6A4;CDK2 GO:0006810| transport ABCB1;SLC6A2 GO:0007420| brain development SLC6A4;BCR 3590:[DB06616 DB13164] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13164|Olmutinib EGFR common genes common pathways GO:0007165| signal transduction MAP2K1;EGFR;BCR;SRC;LYN GO:0070372| regulation of ERK1 and ERK2 cascade LYN;EGFR GO:0006979| response to oxidative stress EGFR;ABL1 GO:1903800| MAP2K1;EGFR;MAP2K2 GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;EGFR;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;EGFR;MAP2K1;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EGFR;HCK;LYN GO:0030335| positive regulation of cell migration EGFR;LYN GO:0098609| EGFR;SRC GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;EGFR;SRC;BCR;ABL1 GO:0034614| cellular response to reactive oxygen species EGFR;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;EGFR;MAP2K1 GO:0008283| cell proliferation EGFR;SRC GO:0014070| response to organic cyclic compound LYN;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;MAP3K2 GO:0008284| positive regulation of cell proliferation EGFR;HCK;CDK2;LYN GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process EGFR;HCK;SRC GO:2000145| regulation of cell motility ABL1;EGFR GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;EGFR GO:0018108| peptidyl-tyrosine phosphorylation SRC;BCR;MAP2K2;HCK;EGFR;MAP2K1;ABL1;LYN GO:0007275| multicellular organismal development EGFR;CDK2;CAMK2G GO:0042127| regulation of cell proliferation SRC;EGFR;ABL1 GO:0038128| SRC;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1;EGFR GO:0001934| positive regulation of protein phosphorylation EGFR;ABL1;LYN GO:0038083| LYN;SRC;HCK;EGFR;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;EGFR;SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;EGFR;MAP2K2;SRC 3591:[DB06616 DB09334] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09334|Seractide acetate MC2R common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;MC2R;LYN 3592:[DB06616 DB03752] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYP2C8;CYP3A4 GO:0006954| inflammatory response HCK;PTGS1;LYN GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006979| response to oxidative stress ABL1;PTGS1 3593:[DB06616 DB04017] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04017|Clorgiline MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4 3594:[DB06616 DB08291] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08291|N-(3-AMINOPROPYL)-2-NITROBENZENAMINE KAT2B common genes common pathways GO:0016032| viral reproduction HCK;SRC;LYN;KAT2B GO:0006355| regulation of transcription, DNA-dependent KAT2B;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;KAT2B;MAP2K2;SRC;MAP2K1 GO:0007050| cell cycle arrest MAP2K1;ABL1;KAT2B GO:0032869| cellular response to insulin stimulus SRC;KAT2B GO:0008285| negative regulation of cell proliferation KAT2B;LYN;MAP2K1 GO:0007049| cell cycle KAT2B;CDK2;SRC 3595:[DB06616 DB00854] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0007165| signal transduction OPRK1;BCR;SRC;MAP2K1;LYN;OPRM1;OPRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;OPRM1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;BCR;SRC GO:0010629| negative regulation of gene expression OPRD1;MAP2K1;MAP2K2 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 3596:[DB06616 DB03150] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03150|2',3'-Dideoxythymidine-5'-Monophosphate DTYMK common genes common pathways GO:0016310| phosphorylation DTYMK;LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0008283| cell proliferation SRC;DTYMK GO:0007049| cell cycle SRC;CDK2;DTYMK 3597:[DB06616 DB04614] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007155| cell adhesion HCK;SRC;ABL1;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0006260| DNA replication ACHE;CDK2 3598:[DB06616 DB00493] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport SLC22A6;SLC15A1;SLC22A8;SLC15A2;ABCB1;SLC22A7;SLC22A11 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation LYN;ALB 3599:[DB06616 DB06848] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways 3600:[DB06616 DB08695] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HPGDS GO:0007165| signal transduction HPGDS;SRC;BCR;MAP2K1;LYN 3601:[DB06616 DB14050] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0006954| inflammatory response LYN;TRPV1;HCK GO:0006816| calcium ion transport TRPV1;TRPV2;TRPA1;CAMK2G GO:0042493| response to drug ABCB1;SRC;TRPA1;LYN GO:0042542| response to hydrogen peroxide TRPA1;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;CDK2 GO:0006629| lipid metabolic process DAGLA;TRPV1;CYP3A4 GO:0010033| response to organic substance TRPA1;CDK2 GO:0014070| response to organic cyclic compound TRPA1;LYN GO:0055085| transmembrane transport TRPV1;TRPV2;ABCB1;TRPA1 GO:0065009| regulation of molecular function TRPV1;CAMK2G GO:0034605| cellular response to heat LYN;TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1;LYN GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;ABL1 GO:0006810| transport ABCB1;TRPV2;TRPV1 3602:[DB06616 DB01245] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0007165| signal transduction LYN;CHRNB2;BCR;SRC;CHRNA4;MAP2K1;CHRNA2 GO:0006979| response to oxidative stress ABL1;CHRNA4 GO:0042493| response to drug LYN;BCHE;SRC;ABCB1 GO:0006260| DNA replication ACHE;CDK2 GO:0006816| calcium ion transport CAMK2G;CHRNB2;CHRNA4 GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0006281| DNA repair CDK2;ABL1;CHRNA4 3603:[DB06616 DB07145] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07145|(2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE ADAM17 common genes common pathways GO:0048536| spleen development ADAM17;ABL1 GO:0030335| positive regulation of cell migration ADAM17;LYN GO:0007155| cell adhesion ADAM17;SRC;HCK;ABL1 GO:0008284| positive regulation of cell proliferation HCK;ADAM17;CDK2;LYN GO:0051272| positive regulation of cellular component movement ADAM17;LYN GO:0032496| response to lipopolysaccharide ADAM17;BCR GO:0048870| cell motility ADAM17;MAP2K1 GO:0001934| positive regulation of protein phosphorylation ADAM17;LYN;ABL1 GO:0042493| response to drug SRC;ABCB1;LYN;ADAM17 GO:0007173| epidermal growth factor receptor signaling pathway ADAM17;SRC;ABL1 3604:[DB06616 DB05785] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0060324| face development RARA;MAP2K1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;ABL1;RARA;RARB;JUN GO:0042493| response to drug JUN;LYN;SRC;ABCB1 GO:0010629| negative regulation of gene expression MAP2K2;RARA;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;RARA;MAP2K1;JUN;MAP3K2;CDK2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;JUN;RARG;HCK;RARB;RARA GO:0071222| cellular response to lipopolysaccharide SRC;BCR;RARA;ABL1 GO:0042542| response to hydrogen peroxide SRC;JUN GO:0051726| regulation of cell cycle ABL1;BCR;SRC;JUN GO:0043065| positive regulation of apoptotic process JUN;RARB;SRC;RARG;ABL1 GO:0043066| negative regulation of apoptotic process RARA;RARB;HCK;SRC;RARG;JUN GO:0009612| response to mechanical stimulus JUN;SRC GO:0071300| cellular response to retinoic acid RARA;RARG;LYN GO:0042981| regulation of apoptotic process MAP2K2;RARA;MAP2K1;MAP3K2 GO:0045597| positive regulation of cell differentiation MAP2K1;JUN GO:0010634| positive regulation of epithelial cell migration SRC;JUN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARG;RARA;RARB GO:0032496| response to lipopolysaccharide JUN;BCR GO:0042127| regulation of cell proliferation JUN;SRC;ABL1 GO:0007265| Ras protein signal transduction JUN;CDK2 GO:0034614| cellular response to reactive oxygen species SRC;JUN GO:0010628| positive regulation of gene expression MAP2K1;RARA;SRC;RARG GO:0045892| negative regulation of transcription, DNA-dependent RARA;SRC;JUN GO:0010033| response to organic substance CDK2;JUN GO:0008285| negative regulation of cell proliferation RARA;MAP2K1;RARB;RARG;JUN;LYN GO:0038095| JUN;LYN GO:0014070| response to organic cyclic compound JUN;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade JUN;ABL1;MAP2K2;SRC;MAP2K1 GO:0007179| transforming growth factor beta receptor signaling pathway JUN;SRC GO:0007165| signal transduction SRC;BCR;RARB;RARA;MAP2K1;LYN GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;JUN GO:0043547| positive regulation of GTPase activity JUN;BCR GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;RARA;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0001843| neural tube closure RARA;ABL1;RARG 3605:[DB06616 DB02580] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02580|Pentaglyme PFN2;gpmA;purA common genes common pathways GO:0051496| positive regulation of stress fiber assembly ABL1;PFN2 GO:0030838| positive regulation of actin filament polymerization PFN2;HCK GO:0030036| actin cytoskeleton organization BCR;ABL1;PFN2 3606:[DB06616 DB08617] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08617|4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE YARS common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;YARS GO:0006915| apoptotic process YARS;ABL1 3607:[DB06616 DB00119] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0016310| phosphorylation PKM;ABL1;HCK;MAP2K1;PKLR;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2 GO:0006810| transport ABCB1;SLC16A2 GO:0032869| cellular response to insulin stimulus PKM;SRC;PKLR GO:0055085| transmembrane transport SLC16A3;SLC16A4;SLCO2A1;SLC16A10;SLC16A8;SLC16A7;SLC16A6;SLC16A1;SLC16A2;SLC16A5;ABCB1 GO:0032868| response to insulin stimulus PKM;LYN GO:0010033| response to organic substance CDK2;PKM GO:0006629| lipid metabolic process CYP3A4;PC;SLC16A1 GO:0010629| negative regulation of gene expression PC;MAP2K2;MAP2K1 GO:0042493| response to drug SRC;ABCB1;ABAT;LYN GO:0055114| oxidation-reduction process PDHB;CYP2C8;CYP3A4 GO:0050900| leukocyte migration SRC;SLC16A1;SLC16A8;SLC16A3;LYN 3608:[DB06616 DB02623] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways GO:0031295| T cell costimulation SRC;CDC42;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;CDC42;SRC GO:0098609| CDC42;SRC GO:0007229| integrin-mediated signaling pathway HCK;CDC42;SRC;ABL1 GO:0006468| protein phosphorylation ABL1;MAP2K2;BCR;CDC42;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0030154| cell differentiation HCK;CDC42;CAMK2G GO:1900026| ABL1;CDC42 GO:0051056| regulation of small GTPase mediated signal transduction CDC42;BCR GO:0090135| actin filament branching CDC42;ABL1 GO:0007596| blood coagulation LYN;CDC42 GO:0051496| positive regulation of stress fiber assembly CDC42;ABL1 GO:0010628| positive regulation of gene expression CDC42;SRC;MAP2K1 GO:0048013| ephrin receptor signaling pathway LYN;CDC42;SRC GO:0038189| ABL1;CDC42 GO:0051149| positive regulation of muscle cell differentiation CDC42;ABL1 GO:0048010| vascular endothelial growth factor receptor signaling pathway CDC42;SRC GO:0006897| endocytosis ABL1;CDC42 GO:0007399| nervous system development CDC42;CAMK2G GO:0010629| negative regulation of gene expression MAP2K1;CDC42;MAP2K2 GO:0034332| adherens junction organization SRC;CDC42 GO:0001934| positive regulation of protein phosphorylation CDC42;ABL1;LYN GO:2000251| positive regulation of actin cytoskeleton reorganization CDC42;HCK;ABL1 GO:0030036| actin cytoskeleton organization BCR;CDC42;ABL1 GO:0038096| LYN;CDC42;SRC;HCK;ABL1 3609:[DB06616 DB01805] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways GO:0006260| DNA replication ACHE;CDK2 GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0007399| nervous system development CAMK2G;ACHE GO:0045785| positive regulation of cell adhesion SRC;PRSS2 GO:0008283| cell proliferation ACHE;SRC 3610:[DB06616 DB02185] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02185|2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One LCTL common genes common pathways 3611:[DB06616 DB11201] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042493| response to drug ABCB1;SRC;PTGS2;LYN GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 3612:[DB06616 DB02418] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways GO:0006464| protein modification process ABL1;UBE2D2 GO:0038095| UBE2D2;LYN GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;UBE2D2;LYN 3613:[DB06616 DB11626] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11626|Tasonermin TNFRSF1A;TNFRSF1B common genes common pathways GO:0071222| cellular response to lipopolysaccharide BCR;SRC;TNFRSF1B;ABL1 GO:0071260| cellular response to mechanical stimulus TNFRSF1A;MAP3K2 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;MAP2K2;TNFRSF1A GO:0042127| regulation of cell proliferation TNFRSF1A;SRC;TNFRSF1B;ABL1 GO:0032496| response to lipopolysaccharide TNFRSF1B;BCR;TNFRSF1A GO:0007275| multicellular organismal development TNFRSF1B;CAMK2G;CDK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;TNFRSF1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFRSF1A;ABL1 GO:0016032| viral reproduction LYN;SRC;TNFRSF1A;HCK GO:0006954| inflammatory response TNFRSF1B;TNFRSF1A;HCK;LYN GO:0050728| negative regulation of inflammatory response TNFRSF1B;BCR;TNFRSF1A GO:0019221| cytokine-mediated signaling pathway TNFRSF1A;HCK GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process TNFRSF1B;SRC GO:0007165| signal transduction LYN;BCR;TNFRSF1A;SRC;MAP2K1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNFRSF1A;ABL1;TNFRSF1B GO:0006915| apoptotic process TNFRSF1A;TNFRSF1B;ABL1 3614:[DB06616 DB04510] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04510|3-phospho-D-glyceric acid PGK1;PGAM2;TPI1 common genes common pathways GO:0071456| cellular response to hypoxia PGK1;SRC GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;PGK1;LYN;CDK2;CAMK2G GO:0007275| multicellular organismal development TPI1;CDK2;CAMK2G 3615:[DB06616 DB00392] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0007399| nervous system development CHRM1;CAMK2G;CHRM2 GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0006816| calcium ion transport GRIN3A;CAMK2G GO:0042493| response to drug LYN;BCHE;SRC;ABCB1 GO:0007165| signal transduction CHRM1;LYN;CHRM2;BCR;SRC;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0006464| protein modification process CHRM1;ABL1 GO:0008283| cell proliferation SRC;CHRM1 3616:[DB06616 DB08632] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways GO:0007596| blood coagulation HBB;LYN GO:0042542| response to hydrogen peroxide SRC;HBA1;HBB 3617:[DB06616 DB09559] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09559|Necitumumab EGFR common genes common pathways GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EGFR;HCK;LYN GO:0098609| EGFR;SRC GO:0030335| positive regulation of cell migration LYN;EGFR GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;EGFR;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle EGFR;ABL1 GO:1903800| MAP2K2;MAP2K1;EGFR GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;EGFR;MAP2K1 GO:0006979| response to oxidative stress EGFR;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;EGFR GO:0007165| signal transduction LYN;EGFR;MAP2K1;SRC;BCR GO:0014070| response to organic cyclic compound LYN;EGFR GO:0008283| cell proliferation EGFR;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;EGFR;ABL1 GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0046777| protein autophosphorylation ABL1;SRC;BCR;EGFR;HCK;CAMK2G;LYN GO:0043406| positive regulation of MAP kinase activity EGFR;SRC GO:0042127| regulation of cell proliferation SRC;EGFR;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;BCR;MAP2K2;SRC;MAP2K1;EGFR;HCK;ABL1 GO:0007275| multicellular organismal development EGFR;CAMK2G;CDK2 GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process EGFR;HCK;SRC GO:2000145| regulation of cell motility ABL1;EGFR GO:0035556| intracellular signal transduction EGFR;BCR;SRC;LYN;CAMK2G GO:0008284| positive regulation of cell proliferation EGFR;HCK;CDK2;LYN GO:0071260| cellular response to mechanical stimulus EGFR;MAP3K2 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;EGFR;MAP2K1;CDK2;MAP3K2 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;EGFR;SRC GO:0038083| LYN;ABL1;HCK;EGFR;SRC GO:0001934| positive regulation of protein phosphorylation EGFR;ABL1;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;EGFR GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;EGFR;MAP2K2 GO:0038128| SRC;EGFR 3618:[DB06616 DB00483] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation HCK;CHRM1;LYN;CDK2 GO:0007399| nervous system development ACHE;CHRM2;CAMK2G;CHRM1 GO:0007155| cell adhesion SRC;HCK;ABL1;ACHE GO:0006260| DNA replication CDK2;ACHE GO:0007165| signal transduction CHRM5;CHRM1;CHRM2;LYN;SRC;BCR;CHRNA2;MAP2K1 GO:0006464| protein modification process ABL1;CHRM1 GO:0008283| cell proliferation CHRM1;ACHE;CHRM5;SRC 3619:[DB06616 DB07297] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways GO:0030097| hemopoiesis LCK;LYN GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;LCK;HCK;MAP2K2;BCR;SRC;ABL1 GO:0030168| platelet activation LYN;SRC;LCK GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;LCK;HCK;MAP2K2;BCR;SRC;ABL1 GO:0031295| T cell costimulation SRC;LCK;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LCK;LYN GO:0050853| B cell receptor signaling pathway ABL1;LCK;LYN GO:0050690| regulation of defense response to virus by virus HCK;LCK GO:0006470| protein dephosphorylation LCK;CAMK2G GO:0016477| cell migration LCK;SRC GO:0045087| innate immune response ABL1;SRC;HCK;LCK;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;LCK;HCK;LYN GO:0042127| regulation of cell proliferation ABL1;LCK;SRC GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC GO:0016032| viral reproduction LYN;SRC;LCK;HCK GO:0050900| leukocyte migration SRC;LCK;LYN GO:0038083| ABL1;SRC;HCK;LCK;LYN GO:0042493| response to drug LYN;LCK;ABCB1;SRC 3620:[DB06616 DB03680] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03680|Tartronate ME2;ME3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ME3;CYP2C8;ME2 3621:[DB06616 DB00416] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways GO:0007165| signal transduction MAP2K1;CHRNA2;BCR;SRC;LYN 3622:[DB06616 DB01914] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;SLC2A1 GO:0016310| phosphorylation MAP3K2;GCK;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;HK1;BCR;SRC;ABL1 GO:0071456| cellular response to hypoxia SLC2A4;SRC GO:0032869| cellular response to insulin stimulus GCK;SLC2A4;SRC GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0006810| transport ABCB1;SLC5A2 GO:0032868| response to insulin stimulus SLC2A1;LYN GO:0055085| transmembrane transport SLC2A11;SLC2A7;SLC5A1;SLC2A5;SLC2A2;SLC2A10;ABCB1;SLC5A2;SLC2A6;SLC2A3;SLC2A9;SLC2A12;SLC2A4;SLC2A1;SLC2A8 3623:[DB06616 DB04005] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;UCK2;SRC;ABL1 3624:[DB06616 DB03376] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03376|'5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 3625:[DB06616 DB06506] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR1A;HCK GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;HTR1A GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008283| cell proliferation SRC;HTR1A GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 3626:[DB06616 DB04917] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04917|Renzapride HTR3A;HTR4 common genes common pathways GO:0007165| signal transduction LYN;HTR4;BCR;SRC;MAP2K1;HTR3A 3627:[DB06616 DB00149] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways GO:0043547| positive regulation of GTPase activity LARS;BCR GO:0006810| transport SLC16A2;ABCB1 GO:0008283| cell proliferation SRC;BCAT1 GO:0055085| transmembrane transport ABCB1;SLC16A2;SLC16A10 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;LCMT1;CDK2 GO:0006464| protein modification process LCMT1;ABL1 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;LCMT1;MAP2K1 GO:0000082| G1/S transition of mitotic cell cycle CDK2;CAMK2G;BCAT1 3628:[DB06616 DB08251] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways GO:0007507| heart development CASP3;MAP2K1 GO:0006974| response to DNA damage stimulus ABL1;CASP3;CDK2;LYN GO:0043065| positive regulation of apoptotic process CASP3;SRC;ABL1 GO:0042542| response to hydrogen peroxide SRC;CASP3 GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR;CASP3 GO:0043066| negative regulation of apoptotic process SRC;HCK;CASP3 GO:0032496| response to lipopolysaccharide CASP3;BCR GO:0001782| B cell homeostasis LYN;CASP3 GO:0030218| erythrocyte differentiation CASP3;LYN GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0042493| response to drug ABCB1;SRC;CASP3;LYN GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0010033| response to organic substance CDK2;CASP3 GO:0006915| apoptotic process ABL1;CASP3 GO:0030182| neuron differentiation ABL1;CASP3;MAP2K1 GO:0030216| keratinocyte differentiation CASP3;MAP2K1 GO:0043200| response to amino acid stimulus CASP3;LYN GO:0014070| response to organic cyclic compound CASP3;LYN 3629:[DB06616 DB00960] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;HTR1A;LYN;CDK2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0042493| response to drug LYN;ABCB1;HTR1B;SRC GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction MAP2K1;BCR;HTR1B;ADRB1;SRC;ADRB3;ADRB2;LYN;HTR1A GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0008283| cell proliferation HTR1A;SRC GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 3630:[DB06616 DB03575] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03575|Phencyclidine GRIN3A;SIGMAR1;CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2B6 GO:0007399| nervous system development SIGMAR1;CAMK2G GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2B6 GO:0006816| calcium ion transport GRIN3A;CAMK2G GO:0055114| oxidation-reduction process CYP2C8;CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2B6;CYP3A4 3631:[DB06616 DB01917] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC GO:0055085| transmembrane transport SLC22A4;ABCB1 GO:0045453| bone resorption SRC;ADRB2 GO:0007165| signal transduction MAP2K1;ADRB1;SRC;BCR;ADRB2;LYN GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0009615| response to virus ODC1;SRC GO:0008284| positive regulation of cell proliferation HCK;ODC1;LYN;CDK2 3632:[DB06616 DB03256] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways 3633:[DB06616 DB08486] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08486|Efaproxiral HBA1;HBB common genes common pathways GO:0042542| response to hydrogen peroxide SRC;HBA1;HBB GO:0007596| blood coagulation LYN;HBB 3634:[DB06616 DB08302] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction BCR;SRC;MAP2K1;PPARG;LYN GO:0014070| response to organic cyclic compound PPARG;LYN GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response SRC;HCK;ABL1;PPARG;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG 3635:[DB06616 DB00943] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00943|Zalcitabine pol;DCK;ALB;SLC22A6;SLC22A7;SLC29A1;SLC29A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A7;SLC22A6 GO:0008283| cell proliferation SRC;SLC29A2 GO:0071456| cellular response to hypoxia SLC29A1;SRC GO:0016310| phosphorylation CAMK2G;DCK;CDK2;LYN;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB 3636:[DB06616 DB07842] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0014070| response to organic cyclic compound LYN;PPARG GO:0007165| signal transduction SRC;BCR;MAP2K1;PPARG;LYN GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0042493| response to drug SRC;ABCB1;LYN;PPARG GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;PPARG;MAP3K2 GO:0043065| positive regulation of apoptotic process PPARG;SRC;ABL1 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0009612| response to mechanical stimulus PPARG;SRC GO:0007507| heart development PPARG;MAP2K1 GO:0045087| innate immune response ABL1;SRC;HCK;PPARG;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0051974| negative regulation of telomerase activity SRC;PPARG 3637:[DB06616 DB09273] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0008285| negative regulation of cell proliferation ADORA2A;LYN;MAP2K1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0006915| apoptotic process ADORA2A;ABL1 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0007596| blood coagulation LYN;ADORA2A GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;BCR;PDE2A;ADORA2A;ADRB2;LYN GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0007417| central nervous system development ADORA2A;LYN;SRC GO:0051924| regulation of calcium ion transport ADORA2A;CAMK2G GO:0006954| inflammatory response LYN;ADORA2A;HCK GO:0050728| negative regulation of inflammatory response ADORA2A;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0006909| phagocytosis ABL1;HCK;ADORA2A GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug SRC;ABCB1;ADORA2A;LYN;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent ABL1;ADORA2A GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0071260| cellular response to mechanical stimulus PDE2A;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PDE2A GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus PDE2A;SRC GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 3638:[DB06616 DB05308] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05308|ANX-510 TYMS common genes common pathways GO:0009636| response to toxin LYN;TYMS GO:0014070| response to organic cyclic compound TYMS;LYN GO:0042493| response to drug LYN;TYMS;SRC;ABCB1 3639:[DB06616 DB04764] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04764|[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE TPSB2 common genes common pathways 3640:[DB06616 DB08289] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08289|N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM-N-OXIDE IGKC common genes common pathways GO:0038095| IGKC;LYN GO:0050853| B cell receptor signaling pathway IGKC;LYN;ABL1 GO:0002376| immune system process IGKC;LYN;SRC;HCK GO:0050900| leukocyte migration IGKC;LYN;SRC GO:0038096| SRC;HCK;ABL1;IGKC;LYN GO:0002250| adaptive immune response IGKC;LYN GO:0045087| innate immune response SRC;HCK;ABL1;IGKC;LYN 3641:[DB06616 DB00732] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00732|Atracurium besylate CHRNA2 common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;CHRNA2;BCR;SRC 3642:[DB06616 DB07302] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0014070| response to organic cyclic compound LYN;PPARG GO:0007165| signal transduction LYN;PPARG;MAP2K1;SRC;BCR GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug SRC;ABCB1;LYN;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;PPARG GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN 3643:[DB06616 DB02166] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02166|Propidium ACHE common genes common pathways GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0006260| DNA replication ACHE;CDK2 GO:0008283| cell proliferation ACHE;SRC 3644:[DB06616 DB14597] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14597|Lanadelumab KLKB1 common genes common pathways GO:0006954| inflammatory response KLKB1;LYN;HCK GO:0007596| blood coagulation LYN;KLKB1 3645:[DB06616 DB07047] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR 3646:[DB06616 DB08897] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08897|Aclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;BCHE common genes common pathways GO:0008283| cell proliferation CHRM4;SRC;CHRM1;CHRM3;CHRM5 GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0007165| signal transduction CHRM5;CHRM3;CHRM1;LYN;CHRM2;BCR;SRC;MAP2K1;CHRM4 GO:0042493| response to drug BCHE;LYN;ABCB1;SRC GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CAMK2G;CHRM1;CHRM2;CHRM3 3647:[DB06616 DB09517] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways GO:0042542| response to hydrogen peroxide HBA1;HBB;SRC GO:0007596| blood coagulation HBB;LYN 3648:[DB06616 DB07144] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 3649:[DB06616 DB04396] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04396|Thiodigalactoside NCAN;LGALS1 common genes common pathways GO:0007417| central nervous system development SRC;NCAN;LYN GO:0031295| T cell costimulation LGALS1;SRC;LYN GO:0007165| signal transduction LYN;BCR;LGALS1;SRC;MAP2K1 GO:0006915| apoptotic process ABL1;LGALS1 GO:0048678| response to axon injury LGALS1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;LGALS1 GO:0007155| cell adhesion ABL1;SRC;HCK;NCAN GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;LGALS1;MAP3K2 GO:0042493| response to drug LYN;ABCB1;SRC;LGALS1 3650:[DB06616 DB07670] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C18;CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C18;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2C18;CYP3A4 3651:[DB06616 DB07643] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07643|5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 3652:[DB06616 DB01079] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01079|Tegaserod HTR4;HTR2B;HTR2C;HTR2A;CYP1A2;CYP2C8;CYP2D6;CYP2E1;SLC6A4 common genes CYP2C8 common pathways GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009636| response to toxin SLC6A4;LYN GO:0002933| CYP3A4;CYP2C8 GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;HTR2C;HTR2B;ABL1;HTR2A GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010628| positive regulation of gene expression SRC;MAP2K1;SLC6A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;SRC GO:0010033| response to organic substance SLC6A4;CDK2;CYP1A2 GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;HTR2B;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8;CYP2D6 GO:0050715| positive regulation of cytokine secretion HTR2B;SRC GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0007420| brain development SLC6A4;BCR GO:0007165| signal transduction HTR2A;LYN;HTR4;HTR2C;HTR2B;BCR;SRC;MAP2K1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug HTR2B;HTR2C;SLC6A4;SRC;ABCB1;LYN;HTR2A;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;HTR2B GO:0016032| viral reproduction LYN;HTR2A;HCK;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0008284| positive regulation of cell proliferation HTR2B;HCK;LYN;CDK2;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;HCK;SRC GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2E1 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0006082| organic acid metabolic process CYP2C8 GO:0007507| heart development MAP2K1;HTR2B GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6 3653:[DB06616 DB06247] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06247|CX516 GRIA1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;GRIA1;LYN 3654:[DB06616 DB07740] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;HMGCS1 GO:0006629| lipid metabolic process CYP3A4;HMGCS1 GO:0010033| response to organic substance CDK2;HMGCS1 GO:0014070| response to organic cyclic compound HMGCS1;LYN GO:0007420| brain development HMGCS1;BCR GO:0009725| response to hormone stimulus HMGCS1;LYN GO:0008202| steroid metabolic process CYP3A4;HMGCS1;CYP2C8 3655:[DB06616 DB02404] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0007399| nervous system development ACHE;CAMK2G GO:0006260| DNA replication CDK2;ACHE 3656:[DB06616 DB04469] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction LYN;PDE4D;SRC;BCR;MAP2K1 GO:0071222| cellular response to lipopolysaccharide PDE4D;ABL1;BCR;SRC GO:0050900| leukocyte migration LYN;PDE4D;SRC 3657:[DB06616 DB00595] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00595|Oxytetracycline rpsI;rpsD;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport SLC22A8;SLC22A6;SLC22A7;SLC22A11;ABCB1 3658:[DB06616 DB06530] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06530|Resiquimod TLR7;TLR8 common genes common pathways GO:0001932| regulation of protein phosphorylation TLR8;MAP2K1;LYN;TLR7 GO:0071260| cellular response to mechanical stimulus TLR7;MAP3K2;TLR8 GO:0045087| innate immune response ABL1;TLR8;SRC;HCK;LYN;TLR7 GO:0009615| response to virus SRC;TLR8 GO:0050707| regulation of cytokine secretion TLR8;LYN GO:0006954| inflammatory response HCK;TLR8;TLR7;LYN GO:0007165| signal transduction BCR;SRC;MAP2K1;TLR8;LYN;TLR7 GO:0002376| immune system process TLR7;LYN;SRC;HCK;TLR8 3659:[DB06616 DB06607] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1;CD3E GO:0007165| signal transduction LYN;FCGR1A;MAP2K1;SRC;BCR GO:0002376| immune system process LYN;CD3E;FCGR2A;FCGR1A;SRC;HCK GO:0060333| interferon-gamma-mediated signaling pathway HCK;FCGR1A;CAMK2G GO:0007172| signal complex assembly CD3E;SRC GO:0031295| T cell costimulation LYN;SRC;CD3E GO:0098609| SRC;EPCAM GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;CD3E GO:0038096| ABL1;FCGR2A;FCGR1A;SRC;HCK;LYN;FCGR3A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;CD3E;SRC;LYN GO:0002250| adaptive immune response CD3E;LYN GO:0050900| leukocyte migration EPCAM;SRC;LYN GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;CD3E GO:0045087| innate immune response ABL1;FCGR1A;SRC;HCK;LYN GO:0042981| regulation of apoptotic process CD3E;MAP2K1;MAP2K2;MAP3K2 GO:0008284| positive regulation of cell proliferation EPCAM;HCK;CDK2;LYN 3660:[DB06616 DB00122] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00122|Choline PCYT1B;ACHE;PCYT1A;PLD2;BCHE;PLD1;PHOSPHO1;CHRNA7;CEPT1;CHKB;CHAT;CHKA;CHDH;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC44A1;SLC44A4;SLC44A2;SLC44A3;SLC5A7 common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0008283| cell proliferation SRC;ACHE GO:0009636| response to toxin LYN;CHKA GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A5;SLC22A3;SLC22A1 GO:0055085| transmembrane transport SLC44A2;ABCB1;SLC44A1;SLC5A7;SLC44A4;SLC22A2;SLC22A4;SLC22A1;SLC22A3;SLC44A3;SLC22A5 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;CHRNA7;ABL1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;CHRNA7;MAP3K2 GO:0007165| signal transduction CHKA;LYN;CHRNA7;SRC;BCR;SLC44A2;MAP2K1 GO:0016310| phosphorylation CAMK2G;CHKA;CDK2;LYN;MAP3K2;ABL1;CHKB;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0006816| calcium ion transport CAMK2G;CHRNA7 GO:0038096| LYN;SRC;HCK;ABL1;PLD2 GO:0006260| DNA replication ACHE;CDK2 GO:0042493| response to drug BCHE;LYN;ABCB1;SRC GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CHDH;CYP3A4 GO:0006935| chemotaxis MAP2K1;PLD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;CDK2;LYN GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0007399| nervous system development ACHE;CAMK2G GO:0006629| lipid metabolic process PCYT1A;CYP3A4;CHKA;CEPT1;PLD2;CHKB;PCYT1B;PLD1 GO:0048870| cell motility PLD2;PLD1;MAP2K1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC44A2;ABL1 GO:0007265| Ras protein signal transduction CDK2;PLD1 3661:[DB06616 DB04801] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04801|cis-Vaccenic acid PPARD common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0007507| heart development PPARD;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARD GO:0043066| negative regulation of apoptotic process SRC;HCK;PPARD GO:0071222| cellular response to lipopolysaccharide PPARD;BCR;SRC;ABL1 GO:0008284| positive regulation of cell proliferation HCK;PPARD;CDK2;LYN GO:0042127| regulation of cell proliferation PPARD;SRC;ABL1 GO:0050728| negative regulation of inflammatory response BCR;PPARD GO:0045893| positive regulation of transcription, DNA-dependent PPARD;MAP3K2;CDK2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARD GO:0030154| cell differentiation HCK;PPARD;CAMK2G GO:0071456| cellular response to hypoxia SRC;PPARD GO:0010033| response to organic substance CDK2;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;SRC GO:0010628| positive regulation of gene expression PPARD;SRC;MAP2K1 GO:0006915| apoptotic process PPARD;ABL1 GO:0008283| cell proliferation PPARD;SRC 3662:[DB06616 DB05391] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05391|liposomal prostaglandin E1 GP1BA common genes common pathways GO:0007596| blood coagulation GP1BA;LYN GO:0030168| platelet activation LYN;GP1BA;SRC GO:0019221| cytokine-mediated signaling pathway HCK;GP1BA GO:0007155| cell adhesion HCK;GP1BA;SRC;ABL1 3663:[DB06616 DB08192] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08192|2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE SRC common genes SRC common pathways GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;BCR;SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0060491| regulation of cell projection assembly SRC GO:0036120| SRC GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0031295| T cell costimulation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0048477| oogenesis SRC GO:0071456| cellular response to hypoxia SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0045453| bone resorption SRC GO:0002376| immune system process SRC;HCK;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1 GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0038083| LYN;SRC;HCK;ABL1 GO:0042493| response to drug ABCB1;SRC;LYN GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration SRC;LYN GO:0016032| viral reproduction LYN;SRC;HCK GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0071498| cellular response to fluid shear stress SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038096| HCK;SRC;ABL1;LYN GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0086098| SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0045087| innate immune response SRC;HCK;ABL1;LYN GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion ABL1;SRC;HCK GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC 3664:[DB06616 DB09421] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09421|Protirelin TRHR common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;TRHR 3665:[DB06616 DB07652] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07652|1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE POLK;rnhA common genes common pathways GO:0006974| response to DNA damage stimulus ABL1;POLK;LYN;CDK2 GO:0006281| DNA repair POLK;ABL1;CDK2 GO:0006260| DNA replication CDK2;POLK 3666:[DB06616 DB08561] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08561|BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE MMP13 common genes common pathways 3667:[DB06616 DB00046] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;IGF1R;LYN GO:0030335| positive regulation of cell migration INSR;IGF1R;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;IGF1R;INSR GO:0016310| phosphorylation CAMK2G;CDK2;LYN;IGF1R;INSR;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;IGF1R;INSR;MAP3K2 GO:0032869| cellular response to insulin stimulus SRC;INSR GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;IGF1R;INSR;CAMK2G;LYN GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;INSR;MAP3K2 GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G;INSR GO:0043066| negative regulation of apoptotic process HCK;SRC;IGF1R GO:0008284| positive regulation of cell proliferation INSR;IGF1R;LYN;CDK2;HCK GO:0032148| activation of protein kinase B activity INSR;SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;INSR;MAP3K2;CDK2 GO:0038083| SRC;HCK;ABL1;IGF1R;INSR;LYN GO:0006355| regulation of transcription, DNA-dependent INSR;ABL1 GO:0001934| positive regulation of protein phosphorylation INSR;LYN;ABL1 GO:0023014| signal transduction via phosphorylation event INSR;LYN 3668:[DB06616 DB13783] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;UGT2B7;PTGS1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0034605| cellular response to heat LYN;PTGS2 GO:0008202| steroid metabolic process CYP3A4;UGT2B7;CYP2C8 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0070542| response to fatty acid PTGS2;SRC 3669:[DB06616 DB00800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0010628| positive regulation of gene expression MAP2K1;SRC;DRD1 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;ADRA2B GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;SRC;MAP2K2;MAP2K1;ABL1 GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:1903351| ABL1;DRD1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction DRD5;MAP2K1;ADRA1A;SRC;BCR;DRD1;ADRA2A;ADRA1B;ADRA1D;ADRA2B;LYN;ADRA2C GO:0030168| platelet activation ADRA2C;ADRA2B;LYN;ADRA2A;SRC GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1B;ABL1;ADRA1A GO:0030335| positive regulation of cell migration DRD1;ADRA2A;LYN GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0042493| response to drug LYN;DRD1;ADRA1A;SRC;ABCB1 GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2C;ADRA2B GO:0035556| intracellular signal transduction CAMK2G;LYN;ADRA1B;BCR;ADRA1A;SRC GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;CDK2;LYN;ADRA1D GO:0007275| multicellular organismal development CAMK2G;CDK2;ADRA1D;ADRA1B GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0001932| regulation of protein phosphorylation DRD1;MAP2K1;LYN 3670:[DB06616 DB07282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 3671:[DB06616 DB02427] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 3672:[DB06616 DB06694] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0042493| response to drug ABCB1;ADRA1A;SRC;LYN GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;ADRA1A;BCR;ADRA1B GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;ADRA1D;CDK2;LYN GO:0032148| activation of protein kinase B activity ADRA2B;ADRA2C;SRC;ADRA2A GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CDK2;CAMK2G GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;LYN GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0008283| cell proliferation ADRA1D;ADRA1B;SRC GO:0006915| apoptotic process ADRA1A;ABL1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;ADRA2B;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;ADRA1A;MAP2K2;MAP2K1;ABL1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction ADRA1A;SRC;BCR;MAP2K1;ADRA2A;ADRA1B;ADRA1D;ADRA2C;LYN;ADRA2B GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0030168| platelet activation ADRA2B;LYN;ADRA2C;ADRA2A;SRC GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A;ADRA1D 3673:[DB06616 DB05289] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05289|Tarenflurbil IKBKG common genes common pathways GO:0006974| response to DNA damage stimulus ABL1;IKBKG;LYN;CDK2 GO:0045087| innate immune response IKBKG;ABL1;HCK;SRC;LYN GO:0009615| response to virus SRC;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ABL1 GO:0016032| viral reproduction SRC;HCK;IKBKG;LYN GO:0006954| inflammatory response LYN;IKBKG;HCK GO:0006355| regulation of transcription, DNA-dependent IKBKG;ABL1 GO:0006915| apoptotic process IKBKG;ABL1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2;IKBKG GO:0038095| IKBKG;LYN 3674:[DB06616 DB00168] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0034605| cellular response to heat LYN;TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1;LYN GO:0006810| transport TRPV1;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TRPV1 GO:0065009| regulation of molecular function TRPV1;CAMK2G GO:0007165| signal transduction MAP2K1;SRC;BCR;TAS1R2;TAS1R3;LYN GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport TRPV1;ABCB1;SLC22A11;SLC22A6;SLC22A8 GO:0043065| positive regulation of apoptotic process ABL1;TRPV1;SRC GO:0006629| lipid metabolic process CYP3A4;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;CDK2 GO:0006816| calcium ion transport CAMK2G;TRPV1 GO:0006954| inflammatory response TRPV1;HCK;LYN 3675:[DB06616 DB07873] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways 3676:[DB06616 DB12307] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process HGF;SRC GO:0000278| mitotic cell cycle ABL1;HGF GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP3A43;CYP3A5;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0010629| negative regulation of gene expression MAP2K1;KDR;MAP2K2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0038083| LYN;ABL1;HCK;KDR;SRC GO:0000165| MAPKKK cascade HGF;MAP2K2;MAP2K1;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade SRC;HGF GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HGF;ABL1;LYN GO:0016032| viral reproduction KDR;HCK;SRC;LYN GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0050728| negative regulation of inflammatory response BCR;HGF GO:0007275| multicellular organismal development KDR;CAMK2G;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation LYN;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR;ABL1;HGF GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:2000573| positive regulation of DNA biosynthetic process SRC;HGF GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0008360| regulation of cell shape KDR;HCK GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0043066| negative regulation of apoptotic process KDR;HCK;SRC;HGF GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR GO:0002576| platelet degranulation LYN;HGF GO:0008284| positive regulation of cell proliferation CDK2;LYN;HGF;KDR;HCK GO:0000187| activation of MAPK activity HGF;MAP2K1;MAP2K2;MAP3K2 GO:0036378| CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;KDR GO:0002933| CYP2C8;CYP3A5;CYP3A7;CYP3A4 GO:0008283| cell proliferation HGF;SRC GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0046777| protein autophosphorylation CAMK2G;LYN;SRC;BCR;HCK;KDR;ABL1 GO:0030154| cell differentiation HCK;KDR;CAMK2G GO:0006468| protein phosphorylation ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0030335| positive regulation of cell migration LYN;HGF;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway KDR;HCK;LYN GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0016310| phosphorylation ABL1;MAP2K1;KDR;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 3677:[DB06616 DB11587] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11587|Etafedrine ADRB2 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC GO:0045453| bone resorption SRC;ADRB2 GO:0007165| signal transduction ADRB2;LYN;MAP2K1;BCR;SRC 3678:[DB06616 DB12436] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12436|Vofopitant TACR1 common genes common pathways GO:0051602| response to electrical stimulus SRC;TACR1 GO:0006954| inflammatory response HCK;TACR1;LYN GO:0010634| positive regulation of epithelial cell migration TACR1;SRC GO:0051496| positive regulation of stress fiber assembly TACR1;ABL1 GO:0014070| response to organic cyclic compound TACR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TACR1 GO:0007165| signal transduction LYN;TACR1;MAP2K1;SRC;BCR GO:0009725| response to hormone stimulus TACR1;LYN 3679:[DB06616 DB06920] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06920|Eribaxaban F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0030335| positive regulation of cell migration F10;LYN GO:0007596| blood coagulation F10;LYN 3680:[DB06616 DB06953] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06953|2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FNTA GO:0042127| regulation of cell proliferation FNTB;SRC;ABL1 3681:[DB06616 DB04105] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04105|N-Heptylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ADH1B;CYP2C8 3682:[DB06616 DB05407] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05407|TBC-3711 EDN1 common genes common pathways GO:0042493| response to drug EDN1;SRC;ABCB1;LYN GO:0032496| response to lipopolysaccharide EDN1;BCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDN1;CDK2 GO:0007507| heart development EDN1;MAP2K1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;EDN1 GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR;EDN1 GO:0071398| cellular response to fatty acid EDN1;SRC GO:0008284| positive regulation of cell proliferation HCK;EDN1;LYN;CDK2 GO:0043200| response to amino acid stimulus LYN;EDN1 GO:0071375| cellular response to peptide hormone stimulus SRC;EDN1 GO:0043406| positive regulation of MAP kinase activity SRC;EDN1 GO:0071456| cellular response to hypoxia SRC;EDN1 GO:0007204| elevation of cytosolic calcium ion concentration EDN1;ABL1 GO:0030335| positive regulation of cell migration EDN1;LYN GO:0010595| positive regulation of endothelial cell migration ABL1;EDN1 3683:[DB06616 DB12555] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12555|Nelotanserin HTR2A common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0042493| response to drug HTR2A;LYN;ABCB1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;HTR2A GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 3684:[DB06616 DB06741] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06741|Gavestinel GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;UGT1A1;UGT1A3;UGT1A9;UGT2B4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2C8 GO:0006810| transport GRIN2B;GRIN2C;GRIN2A;ABCB1 GO:0017144| drug metabolic process UGT1A3;CYP2C8;UGT1A9;UGT1A1;CYP3A4 GO:0065009| regulation of molecular function GRIN2A;CAMK2G;GRIN2B;GRIN2C;GRIN2D;GRIN1 GO:0014070| response to organic cyclic compound UGT1A1;LYN GO:0048013| ephrin receptor signaling pathway GRIN1;LYN;GRIN2B;SRC GO:0010033| response to organic substance CDK2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;BCR GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0043065| positive regulation of apoptotic process GRIN1;GRIN2A;ABL1;SRC GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;UGT2B4;UGT1A9 GO:0042493| response to drug SRC;ABCB1;GRIN2A;UGT1A1;LYN GO:1901216| ABL1;GRIN2B GO:0050885| neuromuscular process controlling balance GRIN2C;BCR;ABL1 GO:0006816| calcium ion transport GRIN1;GRIN3A;CAMK2G;GRIN2A GO:0051924| regulation of calcium ion transport CAMK2G;GRIN3B GO:0000165| MAPKKK cascade GRIN2A;MAP2K1;MAP2K2;GRIN2B;CAMK2G;GRIN2D;GRIN1;GRIN2C 3685:[DB06616 DB06737] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways GO:0008202| steroid metabolic process UGT2B7;CYP2C8;CYP2C9;CYP3A4 GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0097267| CYP2C8;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;PTGS1;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0006954| inflammatory response LYN;PTGS1;HCK GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;PTGS1;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS1;UGT2B7 3686:[DB06616 DB08655] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CREBBP GO:0042981| regulation of apoptotic process MAP3K2;CREBBP;MAP2K2;MAP2K1 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;CREBBP;LYN GO:0016032| viral reproduction CREBBP;LYN;HCK;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;CREBBP GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;MAP3K2;CDK2;CREBBP GO:1900034| CREBBP;CAMK2G GO:0007165| signal transduction SRC;BCR;MAP2K1;CREBBP;LYN GO:0031648| protein destabilization SRC;CREBBP 3687:[DB06616 DB02360] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;SRC;MAP2K2;BCR;CTSG;HCK;MAP2K1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;CTSG;SRC GO:0032496| response to lipopolysaccharide BCR;CTSG 3688:[DB06616 DB01866] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01866|RU79256 SRC common genes SRC common pathways GO:0071498| cellular response to fluid shear stress SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071803| positive regulation of podosome assembly SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038096| LYN;ABL1;SRC;HCK GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:0038128| SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction LYN;HCK;SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration LYN;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0038083| LYN;ABL1;SRC;HCK GO:0042493| response to drug LYN;ABCB1;SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0033625| positive regulation of integrin activation SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045087| innate immune response ABL1;SRC;HCK;LYN GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion ABL1;HCK;SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0060065| uterus development SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0086098| SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;SRC;BCR;HCK GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1 GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0048477| oogenesis SRC GO:0071456| cellular response to hypoxia SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0036120| SRC GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0031295| T cell costimulation SRC;LYN 3689:[DB06616 DB07053] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction PPARG;LYN;BCR;SRC;MAP2K1 GO:0014070| response to organic cyclic compound LYN;PPARG GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0007507| heart development MAP2K1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response HCK;SRC;ABL1;LYN;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0009612| response to mechanical stimulus PPARG;SRC GO:0042493| response to drug SRC;ABCB1;PPARG;LYN GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;PPARG 3690:[DB06616 DB01251] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;ABCC8;KCNJ8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0007507| heart development KCNJ8;MAP2K1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2C9 GO:0042493| response to drug ABCB1;SRC;LYN;ABCC8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006813| potassium ion transport KCNJ8;CDK2;ABCC8 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;ABCC8 GO:0055085| transmembrane transport ABCB1;ABCC8 GO:0032868| response to insulin stimulus ABCC8;LYN 3691:[DB06616 DB07265] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07265|3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID WEE1 common genes common pathways GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;WEE1;LYN;CDK2;CAMK2G GO:0016310| phosphorylation MAP3K2;CDK2;LYN;WEE1;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;WEE1;ABCB1 GO:0007049| cell cycle WEE1;CDK2;SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;WEE1;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0051726| regulation of cell cycle BCR;SRC;ABL1;WEE1 GO:0000278| mitotic cell cycle WEE1;ABL1 GO:0000082| G1/S transition of mitotic cell cycle CAMK2G;CDK2;WEE1 GO:0051301| cell division WEE1;CDK2 3692:[DB06616 DB07450] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07450|(R)-minalrestat AKR1B1 common genes common pathways GO:0010033| response to organic substance CDK2;AKR1B1 GO:0055114| oxidation-reduction process CYP3A4;AKR1B1;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;HCK;AKR1B1 3693:[DB06616 DB04942] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARA;RARB;HCK;SRC GO:0071300| cellular response to retinoic acid LYN;RARA GO:0008284| positive regulation of cell proliferation LYN;CDK2;RARA;HCK;RARB GO:0071222| cellular response to lipopolysaccharide RARA;SRC;BCR;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;RARB GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;RARA;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARB;RARA GO:0007275| multicellular organismal development CRABP1;CDK2;CAMK2G GO:0060324| face development RARA;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;RARA;MAP2K1;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent RARA;RARB;ABL1 GO:0010629| negative regulation of gene expression RARA;MAP2K1;MAP2K2 GO:0007165| signal transduction SRC;BCR;RARB;MAP2K1;RARA;LYN;CRABP1 GO:0001843| neural tube closure ABL1;RARA GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;MAP2K1;RARA;HCK;MAP2K2;BCR;SRC GO:0010628| positive regulation of gene expression MAP2K1;RARA;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;RARA GO:0008285| negative regulation of cell proliferation LYN;RARB;RARA;MAP2K1 3694:[DB06616 DB06943] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06943|(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol ADAM17 common genes common pathways GO:0042493| response to drug LYN;ADAM17;SRC;ABCB1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;ADAM17 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;ADAM17 GO:0032496| response to lipopolysaccharide ADAM17;BCR GO:0048870| cell motility ADAM17;MAP2K1 GO:0008284| positive regulation of cell proliferation HCK;ADAM17;LYN;CDK2 GO:0051272| positive regulation of cellular component movement LYN;ADAM17 GO:0007155| cell adhesion HCK;SRC;ABL1;ADAM17 GO:0030335| positive regulation of cell migration ADAM17;LYN GO:0048536| spleen development ADAM17;ABL1 3695:[DB06616 DB00735] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00735|Naftifine SQLE common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;SQLE GO:0010033| response to organic substance SQLE;CDK2 3696:[DB06616 DB02846] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02846|L-thioproline ANXA5 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ANXA5 GO:0007596| blood coagulation LYN;ANXA5 GO:0010033| response to organic substance ANXA5;CDK2 GO:0043066| negative regulation of apoptotic process SRC;HCK;ANXA5 GO:0002576| platelet degranulation LYN;ANXA5 3697:[DB06616 DB03673] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03673|Beta(2-Thienyl)Alanine PAH common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PAH 3698:[DB06616 DB04867] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04867|Lintitript CCKAR common genes common pathways GO:0030900| forebrain development CCKAR;SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;CCKAR;LYN GO:0007204| elevation of cytosolic calcium ion concentration CCKAR;ABL1 3699:[DB06616 DB00770] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;ABCC4 GO:0055114| oxidation-reduction process CYP2C8;ABCC4;CYP3A4 GO:0042127| regulation of cell proliferation ABL1;PTGER2;SRC GO:0032496| response to lipopolysaccharide BCR;PTGER2;PTGER1 GO:0002576| platelet degranulation ABCC4;LYN GO:0006935| chemotaxis MAP2K1;PTGDR2 GO:0014070| response to organic cyclic compound ABCC4;LYN GO:0055085| transmembrane transport SLC22A6;SLCO3A1;SLCO2A1;ABCB1;ABCC4;SLCO2B1;ABCC5 GO:0010033| response to organic substance ABCC4;CDK2 GO:0006810| transport ABCB1;ABCC5 GO:0007165| signal transduction PTGDR2;PTGER2;SRC;BCR;MAP2K1;LYN;PTGER1 3700:[DB06616 DB05956] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0048013| ephrin receptor signaling pathway SRC;LYN;GRIN2B GO:0065009| regulation of molecular function CAMK2G;GRIN2B GO:0006810| transport ABCB1;GRIN2B GO:0016032| viral reproduction RXRA;LYN;HCK;SRC GO:0000165| MAPKKK cascade CAMK2G;GRIN2B;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;RXRA GO:1901216| ABL1;GRIN2B GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;RXRA;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;CDK2 GO:0007507| heart development RXRA;MAP2K1 3701:[DB06616 DB07416] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07416|(2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE IGKC common genes common pathways GO:0050900| leukocyte migration IGKC;LYN;SRC GO:0038096| IGKC;LYN;SRC;HCK;ABL1 GO:0002250| adaptive immune response IGKC;LYN GO:0045087| innate immune response IGKC;LYN;SRC;HCK;ABL1 GO:0038095| LYN;IGKC GO:0050853| B cell receptor signaling pathway LYN;IGKC;ABL1 GO:0002376| immune system process IGKC;LYN;SRC;HCK 3702:[DB06616 DB04967] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0006260| DNA replication CDK2;TOP1 GO:0016032| viral reproduction SRC;HCK;LYN;TOP1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;APEX1 GO:0042493| response to drug ABCB1;APEX1;SRC;LYN;TOP1 GO:0006355| regulation of transcription, DNA-dependent ABL1;APEX1 GO:0042981| regulation of apoptotic process MAP2K1;APEX1;MAP2K2;MAP3K2 GO:0006281| DNA repair CDK2;ABL1;APEX1 GO:0006974| response to DNA damage stimulus ABL1;APEX1;CDK2;LYN;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;ABL1;SRC GO:0018105| peptidyl-serine phosphorylation TOP1;CAMK2G;CDK2;SRC GO:0071375| cellular response to peptide hormone stimulus APEX1;SRC GO:0070301| cellular response to hydrogen peroxide APEX1;ABL1 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;TOP1;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 3703:[DB06616 DB07422] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;AR GO:0006810| transport AR;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;SRC;MAP2K2;MAP2K1;AR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;AR GO:0042327| positive regulation of phosphorylation LYN;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0051259| protein oligomerization AR;CAMK2G 3704:[DB06616 DB07205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07205|N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE YARS common genes common pathways GO:0006915| apoptotic process ABL1;YARS GO:0007165| signal transduction BCR;SRC;YARS;MAP2K1;LYN 3705:[DB06616 DB06094] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06094|Apatorsen HSPB1 common genes common pathways GO:0006928| cellular component movement MAP2K1;HSPB1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1;HSPB1 GO:0009615| response to virus HSPB1;SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;HSPB1;BCR;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;HSPB1 GO:0043066| negative regulation of apoptotic process HSPB1;HCK;SRC GO:0001932| regulation of protein phosphorylation MAP2K1;LYN;HSPB1 GO:0010506| regulation of autophagy HSPB1;ABL1 3706:[DB06616 DB05390] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05390|INS 316 P2RY2 common genes common pathways GO:0007165| signal transduction LYN;P2RY2;MAP2K1;SRC;BCR 3707:[DB06616 DB04974] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04974|AP1903 MTOR common genes common pathways GO:0071456| cellular response to hypoxia SRC;MTOR GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;MTOR;CAMK2G;LYN;CDK2 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MTOR;MAP3K2 GO:0007050| cell cycle arrest MTOR;ABL1;MAP2K1 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;MTOR GO:0007420| brain development MTOR;BCR GO:1900034| CAMK2G;MTOR GO:0032956| regulation of actin cytoskeleton organization ABL1;MTOR GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MTOR;MAP2K1 GO:0032868| response to insulin stimulus LYN;MTOR GO:0051496| positive regulation of stress fiber assembly MTOR;ABL1 GO:0043200| response to amino acid stimulus MTOR;LYN GO:0010628| positive regulation of gene expression MTOR;SRC;MAP2K1 GO:0046777| protein autophosphorylation MTOR;CAMK2G;LYN;SRC;BCR;HCK;ABL1 GO:0009791| post-embryonic development ABL1;MTOR GO:0001933| negative regulation of protein phosphorylation MTOR;LYN GO:0030838| positive regulation of actin filament polymerization MTOR;HCK GO:0001932| regulation of protein phosphorylation LYN;MTOR;MAP2K1 GO:0006281| DNA repair ABL1;CDK2;MTOR GO:0032148| activation of protein kinase B activity MTOR;SRC GO:0060252| positive regulation of glial cell proliferation LYN;MTOR GO:0018105| peptidyl-serine phosphorylation MTOR;CDK2;CAMK2G;SRC GO:0001934| positive regulation of protein phosphorylation MTOR;LYN;ABL1 GO:1901216| ABL1;MTOR GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MTOR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;MTOR GO:0010976| positive regulation of neuron projection development LYN;MTOR 3708:[DB06616 DB00417] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1 GO:0006810| transport SLC15A1;ABCB1 3709:[DB06616 DB02234] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02234|S-Ethylisothiourea NOS2;NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;NOS3;LYN GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;NOS3;HCK GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation SRC;ABL1;NOS2 GO:0043542| endothelial cell migration ABL1;NOS3 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4;NOS2 3710:[DB06616 DB11691] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0002933| CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0006855| drug transmembrane transport ABCB5;ABCB1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0055085| transmembrane transport ABCB5;ABCB1 GO:0036378| CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K1;MAP2K2;SRC;ABL1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP3A5 GO:0017144| drug metabolic process UGT1A3;CYP2C8;CYP3A4 GO:0007165| signal transduction OPRK1;MAP2K1;SRC;BCR;LYN;OPRD1;OPRM1 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0030154| cell differentiation CAMK2G;HCK;ABCB5 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0042908| xenobiotic transport ABCB5;ABCB1 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;MAP2K2;MAP2K1 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP3A43;CYP2C8;CYP3A5 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;OPRK1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP2C8;CYP3A5 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 3711:[DB06616 DB04471] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0060065| uterus development ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0007165| signal transduction ESR1;LYN;SRC;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 3712:[DB06616 DB08045] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08045|4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL HSP90AB1 common genes common pathways GO:0010033| response to organic substance CDK2;HSP90AB1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;HSP90AB1 GO:1900034| HSP90AB1;CAMK2G GO:0042493| response to drug LYN;HSP90AB1;ABCB1;SRC GO:0038096| LYN;HSP90AB1;ABL1;HCK;SRC GO:0045597| positive regulation of cell differentiation MAP2K1;HSP90AB1 GO:0043066| negative regulation of apoptotic process HSP90AB1;SRC;HCK GO:0006805| xenobiotic metabolic process CYP2C8;HSP90AB1;CYP3A4 3713:[DB06616 DB06885] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 3714:[DB06616 DB02263] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways GO:0055085| transmembrane transport SLCO2A1;ABCB1 3715:[DB06616 DB03072] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03072|2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone PARP1 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:0006915| apoptotic process PARP1;ABL1 GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:1900182| PARP1;SRC GO:1901216| ABL1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0006974| response to DNA damage stimulus ABL1;PARP1;LYN;CDK2 GO:0006281| DNA repair ABL1;CDK2;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PARP1 3716:[DB06616 DB06311] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06311|Darapladib PLA2G4A common genes common pathways GO:0042127| regulation of cell proliferation PLA2G4A;SRC;ABL1 GO:0006629| lipid metabolic process CYP3A4;PLA2G4A 3717:[DB06616 DB02696] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways GO:0008285| negative regulation of cell proliferation B4GALT1;LYN;MAP2K1 GO:0007155| cell adhesion ABL1;HCK;SRC;B4GALT1 GO:0043065| positive regulation of apoptotic process B4GALT1;SRC;ABL1 GO:0042127| regulation of cell proliferation B4GALT1;SRC;ABL1 GO:0050900| leukocyte migration SRC;LYN;B4GALT1 3718:[DB06616 DB08121] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development PPARG;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;PPARG;MAP3K2 GO:0042493| response to drug SRC;ABCB1;PPARG;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PPARG GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0014070| response to organic cyclic compound LYN;PPARG 3719:[DB06616 DB03192] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HSD17B4 GO:0055114| oxidation-reduction process CYP3A4;HSD17B4;CYP2C8 GO:0008209| androgen metabolic process HSD17B4;CYP3A4 3720:[DB06616 DB14515] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14515|Magnesium lactate ATP1A1 common genes common pathways GO:0006813| potassium ion transport CDK2;ATP1A1 GO:0042493| response to drug ATP1A1;LYN;ABCB1;SRC GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 3721:[DB06616 DB06985] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways GO:0060065| uterus development SRC;RBP4 GO:0007507| heart development MAP2K1;RBP4 3722:[DB06616 DB03405] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03405|N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 3723:[DB06616 DB11157] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11157|Anthralin KRT2;MAPK8IP1;KRT12 common genes common pathways GO:0007165| signal transduction LYN;MAPK8IP1;MAP2K1;BCR;SRC GO:0043066| negative regulation of apoptotic process MAPK8IP1;HCK;SRC GO:0006355| regulation of transcription, DNA-dependent MAPK8IP1;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MAPK8IP1;SRC 3724:[DB06616 DB08550] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08550|7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline PNMT common genes common pathways 3725:[DB06616 DB03267] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0032868| response to insulin stimulus PCK1;LYN GO:0032869| cellular response to insulin stimulus PCK1;SRC GO:0071456| cellular response to hypoxia SRC;PCK1 GO:0032496| response to lipopolysaccharide PCK1;BCR GO:0071300| cellular response to retinoic acid LYN;PCK1 GO:0006629| lipid metabolic process PCK1;CYP3A4 3726:[DB06616 DB00536] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00536|Guanidine argG;GAMT;RNASE1;DLG4;ALDH2;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A8;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0045184| establishment of protein localization ABL1;DLG4 GO:0055085| transmembrane transport SLC22A1;SLC22A4;SLC22A3;SLC22A5;SLC22A8;DLG4;SLC47A1;ABCB1;SLC22A2;SLC47A2 GO:0006855| drug transmembrane transport SLC22A5;SLC22A3;SLC22A1;SLC47A2;SLC22A2;ABCB1;SLC47A1 GO:0009636| response to toxin LYN;SLC22A8 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;DLG4 GO:0007165| signal transduction DLG4;LYN;SRC;BCR;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;ALDH2 GO:0050885| neuromuscular process controlling balance ABL1;BCR;DLG4 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;DLG4;CAMK2G GO:0007399| nervous system development CAMK2G;DLG4 3727:[DB06616 DB12569] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12569|Tonapofylline ADORA1 common genes common pathways GO:0043066| negative regulation of apoptotic process ADORA1;HCK;SRC GO:0007399| nervous system development ADORA1;CAMK2G GO:0006954| inflammatory response LYN;ADORA1;HCK GO:0050728| negative regulation of inflammatory response BCR;ADORA1 GO:0006909| phagocytosis ABL1;HCK;ADORA1 GO:0007165| signal transduction LYN;ADORA1;MAP2K1;SRC;BCR GO:0000186| activation of MAPKK activity MAP3K2;ADORA1 GO:0008285| negative regulation of cell proliferation LYN;ADORA1;MAP2K1 3728:[DB06616 DB03008] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03008|5-fluoro-beta-L-gulosyl fluoride MAN2A1 common genes common pathways 3729:[DB06616 DB00882] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes ABCB1 common pathways GO:0009615| response to virus CYP1A1;SRC GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0060065| uterus development SRC;CYP19A1;ESR1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP1A1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP11A1;CYP3A4 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide BCR;CYP1A2;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2E1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0042493| response to drug SRC;ABCB1;CYP1A1;CYP2E1;LYN;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1;CYP3A4;CYP19A1;CYP11A1;CYP1A2;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP2E1;CYP1A1;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ESR1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP1A1;CYP2E1;CYP11A1;CYP1A2;CYP2C8 GO:0045332| phospholipid translocation ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4;CYP11A1 GO:0010033| response to organic substance CDK2;CYP1A1;CYP1A2 GO:0008283| cell proliferation CYP1A1;SRC GO:0014070| response to organic cyclic compound CYP1A1;LYN;CYP1A2 GO:0009636| response to toxin CYP1A1;LYN GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 3730:[DB06616 DB09224] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09224|Melperone DRD2;CYP2D6 common genes common pathways GO:0042493| response to drug LYN;DRD2;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0048678| response to axon injury LYN;DRD2 GO:0035556| intracellular signal transduction CAMK2G;LYN;DRD2;SRC;BCR GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0009636| response to toxin LYN;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;DRD2;SRC;MAP2K1 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction LYN;MAP2K1;DRD2;SRC;BCR GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0030900| forebrain development SRC;DRD2 3731:[DB06616 DB03882] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03882|5-Alpha-Androstane-3-Beta,17beta-Diol ESR2;SHBG common genes common pathways GO:0007165| signal transduction ESR2;MAP2K1;SRC;BCR;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;ESR2;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC 3732:[DB06616 DB07234] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways GO:0006954| inflammatory response MAPKAPK2;HCK;LYN GO:0000165| MAPKKK cascade MAP2K1;MAPKAPK2;MAP2K2;CAMK2G GO:0048010| vascular endothelial growth factor receptor signaling pathway MAPKAPK2;SRC GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;MAPKAPK2;SRC GO:0006974| response to DNA damage stimulus CDK2;LYN;MAPKAPK2;ABL1 GO:0032496| response to lipopolysaccharide MAPKAPK2;BCR GO:0007265| Ras protein signal transduction CDK2;MAPKAPK2 GO:0046777| protein autophosphorylation HCK;MAPKAPK2;BCR;SRC;ABL1;LYN;CAMK2G GO:0000187| activation of MAPK activity MAP3K2;MAPKAPK2;MAP2K1;MAP2K2 GO:1900034| CAMK2G;MAPKAPK2 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;MAPKAPK2;HCK GO:0006468| protein phosphorylation MAP2K1;MAPKAPK2;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G 3733:[DB06616 DB05284] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05284|CA4P TUBB common genes common pathways GO:0006928| cellular component movement MAP2K1;TUBB GO:0000086| G2/M transition of mitotic cell cycle CDK2;TUBB;ABCB1 GO:0051301| cell division TUBB;CDK2 GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB;CDK2 3734:[DB06616 DB08498] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0030216| keratinocyte differentiation MAP2K1;CASP3 GO:0030182| neuron differentiation ABL1;MAP2K1;CASP3 GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0006915| apoptotic process CASP3;ABL1 GO:0010033| response to organic substance CDK2;CASP3 GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0042493| response to drug LYN;ABCB1;SRC;CASP3 GO:0048011| nerve growth factor receptor signaling pathway CASP3;SRC GO:0001782| B cell homeostasis LYN;CASP3 GO:0030218| erythrocyte differentiation LYN;CASP3 GO:0032496| response to lipopolysaccharide BCR;CASP3 GO:0043065| positive regulation of apoptotic process ABL1;CASP3;SRC GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0035556| intracellular signal transduction CASP3;BCR;SRC;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process SRC;HCK;CASP3 GO:0007507| heart development CASP3;MAP2K1 GO:0006974| response to DNA damage stimulus ABL1;CASP3;LYN;CDK2 3735:[DB06616 DB01969] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 3736:[DB06616 DB00172] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0042981| regulation of apoptotic process PPIF;MAP2K1;MAP2K2;MAP3K2 GO:0043066| negative regulation of apoptotic process PPIF;SRC;HCK GO:0034599| cellular response to oxidative stress PYCR2;PYCR1;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway PPIF;SRC GO:0016032| viral reproduction HCK;SRC;LYN;PPIA GO:0055114| oxidation-reduction process CYP3A4;P3H3;P3H2;P4HA2;PYCR2;PYCR1;CYP2C8;P4HA1;P3H1;PRODH GO:0050900| leukocyte migration SRC;LYN;PPIA GO:0006979| response to oxidative stress PPIF;ABL1 GO:0006810| transport SLC6A7;SLC6A14;ABCB1 GO:0008285| negative regulation of cell proliferation MAP2K1;P3H1;P3H3;LYN;P3H2 GO:0070301| cellular response to hydrogen peroxide ABL1;PPIF GO:0006915| apoptotic process PPIF;ABL1 GO:0055085| transmembrane transport SLC16A10;ABCB1;SLC6A14 GO:0009636| response to toxin SLC6A14;LYN 3737:[DB06616 DB01989] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways GO:0030154| cell differentiation HCK;CAMK2G;TLL2 GO:0007275| multicellular organismal development TLL2;CAMK2G;CDK2 3738:[DB06616 DB00269] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0060065| uterus development SRC;CYP19A1;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ESR1;MAP3K2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC 3739:[DB06616 DB07906] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07906|[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL PNMT common genes common pathways 3740:[DB06616 DB02419] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways GO:0016032| viral reproduction HCK;SRC;LYN;PPIA GO:0050900| leukocyte migration SRC;PPIA;LYN 3741:[DB06616 DB12128] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12128|Ulimorelin GHSR common genes common pathways GO:0050728| negative regulation of inflammatory response BCR;GHSR GO:0071222| cellular response to lipopolysaccharide ABL1;GHSR;SRC;BCR GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;GHSR GO:0009725| response to hormone stimulus GHSR;LYN GO:0032869| cellular response to insulin stimulus SRC;GHSR 3742:[DB06616 DB07405] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NOS2 GO:0055114| oxidation-reduction process NOS2;CYP3A4;CYP2C8 GO:0010629| negative regulation of gene expression NOS2;MAP2K1;MAP2K2 3743:[DB06616 DB08746] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08746|1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE F10 common genes common pathways GO:0030335| positive regulation of cell migration F10;LYN GO:0007596| blood coagulation F10;LYN GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC 3744:[DB06616 DB00711] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0006979| response to oxidative stress ABL1;PTGS1 GO:0042493| response to drug SRC;ABCB1;LYN;BCHE GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGS1;ALOX5 GO:0006954| inflammatory response ALOX5;PTGS1;HCK;LYN GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4 3745:[DB06616 DB01326] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01326|Cefamandole SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport ABCB1;SLC22A11;SLC22A7;SLC22A6;SLC22A8 3746:[DB06616 DB07627] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07627|(2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPN1;LYN;CDK2;HCK 3747:[DB06616 DB05420] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0051259| protein oligomerization CAMK2G;RRM1 GO:0006260| DNA replication CDK2;RRM1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;RRM1 GO:0000278| mitotic cell cycle RRM1;ABL1 3748:[DB06616 DB03187] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 3749:[DB06616 DB07329] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07329|1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID IGHG2 common genes common pathways GO:0045087| innate immune response LYN;IGHG2;ABL1;HCK;SRC GO:0038096| ABL1;HCK;SRC;LYN;IGHG2 GO:0002250| adaptive immune response IGHG2;LYN GO:0002376| immune system process HCK;SRC;IGHG2;LYN GO:0050853| B cell receptor signaling pathway ABL1;LYN;IGHG2 3750:[DB06616 DB05798] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways GO:0007596| blood coagulation LYN;PRKAR2A;PRKAR1A GO:0001932| regulation of protein phosphorylation MAP2K1;PRKAR1A;PRKAR2A;LYN GO:0007507| heart development PRKAR1A;MAP2K1 GO:0035556| intracellular signal transduction PRKAR1A;PRKAR2A;CAMK2G;LYN;BCR;SRC 3751:[DB06616 DB05533] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05533|QR-333 AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 3752:[DB06616 DB07733] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways GO:0006915| apoptotic process ABL1;CASP1 GO:0007165| signal transduction CASP1;LYN;BCR;SRC;MAP2K1 GO:0050715| positive regulation of cytokine secretion CASP1;SRC GO:0010506| regulation of autophagy ABL1;CASP1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;CASP1 GO:0071260| cellular response to mechanical stimulus MAP3K2;CASP1 GO:0051882| mitochondrial depolarization ABL1;CASP1 GO:0050727| regulation of inflammatory response HCK;CASP1;LYN GO:0071222| cellular response to lipopolysaccharide CASP1;ABL1;SRC;BCR GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;ABL1 GO:0032496| response to lipopolysaccharide CASP1;BCR 3753:[DB06616 DB14012] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14012|Burosumab FGF23 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;MAP2K2;FGF23;MAP2K1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;FGF23;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade FGF23;SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;FGF23;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;FGF23;MAP2K1;ABL1 GO:0042359| vitamin D metabolic process FGF23;CYP3A4 GO:0030154| cell differentiation CAMK2G;FGF23;HCK 3754:[DB06616 DB07978] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0043065| positive regulation of apoptotic process SRC;DHODH;ABL1 GO:0042493| response to drug ABCB1;SRC;DHODH;LYN GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 3755:[DB06616 DB11300] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11300|Thrombin F2R;F2RL3;F11;F13A1;F13B;FGA;FGB;FGG;F5;F8 common genes common pathways GO:0002576| platelet degranulation F13A1;FGB;FGA;F5;LYN;F8;FGG GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;F2R GO:0045087| innate immune response ABL1;FGA;HCK;SRC;FGB;LYN GO:0032496| response to lipopolysaccharide BCR;F2R GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade F2R;ABL1 GO:0006954| inflammatory response LYN;F2R;HCK GO:0002250| adaptive immune response FGA;FGB;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;F2R;MAP3K2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;F8 GO:1900026| FGG;FGA;FGB;ABL1 GO:0002376| immune system process HCK;FGA;FGB;SRC;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol F2R;F2RL3;ABL1 GO:0007165| signal transduction FGG;F2R;F2RL3;LYN;BCR;SRC;FGB;MAP2K1;FGA GO:0043547| positive regulation of GTPase activity BCR;F2R GO:0030335| positive regulation of cell migration F2R;LYN GO:0000186| activation of MAPKK activity MAP3K2;F2R GO:0030168| platelet activation FGA;FGB;SRC;FGG;F8;LYN;F2RL3;F2R GO:0007204| elevation of cytosolic calcium ion concentration ABL1;F2R GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;F2R GO:2000352| negative regulation of endothelial cell apoptosis FGG;FGB;FGA;ABL1 GO:0007596| blood coagulation FGG;F13B;F8;LYN;F2R;F2RL3;FGA;F5;F11;FGB;F13A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade F2R;FGG;ABL1;MAP2K1;FGA;MAP2K2;FGB;SRC 3756:[DB06616 DB05025] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0010033| response to organic substance CDK2;SOD1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;SOD1;MAP3K2 GO:0048538| thymus development SOD1;ABL1;MAP2K1 GO:0006979| response to oxidative stress SOD1;ABL1 GO:0042493| response to drug LYN;SOD1;SRC;ABCB1 GO:0031667| response to nutrient levels SOD1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;SOD1 GO:0042542| response to hydrogen peroxide SOD1;SRC GO:0002576| platelet degranulation LYN;SOD1 GO:0043065| positive regulation of apoptotic process SOD1;ABL1;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;SOD1 GO:0034599| cellular response to oxidative stress SOD1;ABL1 GO:0048678| response to axon injury SOD1;LYN 3757:[DB06616 DB06824] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06824|Triethylenetetramine GPC1 common genes common pathways GO:0050900| leukocyte migration SRC;LYN;GPC1 GO:0007411| axon guidance SRC;GPC1 3758:[DB06616 DB06245] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways GO:0001934| positive regulation of protein phosphorylation LYN;ANXA2;PLAUR;ABL1 GO:0050900| leukocyte migration SRC;FN1;LYN GO:0006909| phagocytosis LRP1;ABL1;HCK GO:0006355| regulation of transcription, DNA-dependent ABL1;CALR GO:0042493| response to drug CALR;LYN;ABCB1;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0002250| adaptive immune response FGA;LYN GO:0034446| substrate adhesion-dependent cell spreading FN1;LAMC1;LAMB1;ABL1;LAMA5;SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;PLAUR GO:0090398| cellular senescence MAP2K1;CALR GO:0016032| viral reproduction SRC;HCK;LYN;KRT8 GO:0007275| multicellular organismal development CAMK2G;CDK2;LRP1 GO:0045056| transcytosis LRP1;SRC GO:0001932| regulation of protein phosphorylation LYN;FN1;MAP2K1 GO:0042127| regulation of cell proliferation LAMA5;SRC;ABL1 GO:0006629| lipid metabolic process CYP3A4;LRP1 GO:0042981| regulation of apoptotic process CALR;MAP3K2;MAP2K1;MAP2K2 GO:0007155| cell adhesion LAMB1;ABL1;LAMA5;SRC;LAMA3;HCK;FN1;LAMC1;LAMA1 GO:0045087| innate immune response LYN;ABL1;FGA;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;CDK2 GO:0008360| regulation of cell shape FN1;HCK GO:0030155| regulation of cell adhesion ABL1;LAMA5;LAMA3;LAMA1 GO:0043066| negative regulation of apoptotic process PLAUR;HCK;SRC;SERPINB2 GO:0071560| cellular response to transforming growth factor beta stimulus CLEC3B;SRC GO:0006897| endocytosis LRP1;ABL1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CALR;FN1 GO:0006935| chemotaxis PLAUR;MAP2K1 GO:0002576| platelet degranulation LYN;FN1;FGA;CLEC3B GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;FGA;MAP2K2;SRC GO:0016477| cell migration LAMC1;SRC;LAMA5 GO:0008283| cell proliferation LRP1;LAMA5;SRC GO:2000352| negative regulation of endothelial cell apoptosis FGA;ABL1 GO:0007596| blood coagulation LYN;F10;PLAUR;FGA GO:0031175| neuron projection development LAMB1;LYN GO:0050766| positive regulation of phagocytosis CALR;BCR GO:0045892| negative regulation of transcription, DNA-dependent CALR;SRC GO:0010033| response to organic substance CALR;CDK2 GO:0006928| cellular component movement PLAUR;MAP2K1 GO:0010628| positive regulation of gene expression FN1;CALR;SRC;MAP2K1 GO:0030168| platelet activation FGA;SRC;LYN GO:0007229| integrin-mediated signaling pathway ABL1;LAMA5;SRC;HCK GO:0036035| osteoclast development ANXA2;SRC GO:0030154| cell differentiation CAMK2G;HCK;LAMA5 GO:0098609| SRC;ANXA2 GO:0030335| positive regulation of cell migration LAMB1;LYN;F10 GO:0010595| positive regulation of endothelial cell migration ABL1;CALR GO:0070372| regulation of ERK1 and ERK2 cascade FN1;LYN GO:0051222| positive regulation of protein transport LRP1;SRC GO:0007165| signal transduction FGA;PLAUR;MAP2K1;SRC;BCR;LYN GO:1900026| CALR;ABL1;FGA GO:0032956| regulation of actin cytoskeleton organization LRP1;ABL1 GO:0002376| immune system process LYN;SRC;HCK;FGA 3759:[DB06616 DB02510] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02510|'5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 3760:[DB06616 DB05424] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05424|Canertinib EGFR common genes common pathways GO:0035556| intracellular signal transduction LYN;CAMK2G;EGFR;BCR;SRC GO:2000145| regulation of cell motility EGFR;ABL1 GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process SRC;EGFR;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;MAP3K2 GO:0042127| regulation of cell proliferation EGFR;SRC;ABL1 GO:0007275| multicellular organismal development EGFR;CAMK2G;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation LYN;EGFR;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC GO:0038128| EGFR;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;EGFR;MAP2K1;MAP3K2;CDK2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;EGFR;ABL1 GO:0038083| LYN;SRC;HCK;EGFR;ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;EGFR;ABL1 GO:0006979| response to oxidative stress EGFR;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;LYN GO:0007165| signal transduction BCR;SRC;MAP2K1;EGFR;LYN GO:0098609| SRC;EGFR GO:0030335| positive regulation of cell migration LYN;EGFR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EGFR;HCK;LYN GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;HCK;EGFR;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0000186| activation of MAPKK activity MAP3K2;EGFR GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:1903800| MAP2K2;MAP2K1;EGFR GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;EGFR;MAP2K2;BCR;SRC GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;EGFR;HCK;ABL1 GO:0043406| positive regulation of MAP kinase activity EGFR;SRC GO:0014070| response to organic cyclic compound EGFR;LYN GO:0008283| cell proliferation SRC;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;EGFR;MAP2K1 3761:[DB06616 DB05219] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes CYP2C8 common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006082| organic acid metabolic process CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2B6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6;CYP2C9 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PDE4B;PDE4D GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2B6;CYP2C8 GO:0050900| leukocyte migration LYN;PDE4D;PDE4B;SRC GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4;CYP2B6 GO:0007165| signal transduction LYN;PDE4D;PDE4A;PDE4B;PDE4C;MAP2K1;SRC;BCR GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9;CYP2B6 GO:0097267| CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2B6;CYP3A4;CYP2C9 GO:0002933| CYP3A4;CYP2C8 3762:[DB06616 DB00890] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00890|Dienestrol ESR1;SHBG common genes common pathways GO:0007165| signal transduction LYN;ESR1;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0060065| uterus development ESR1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 3763:[DB06616 DB05469] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0006915| apoptotic process ABL1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;ADRA1A;SRC GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A;ADRA1D GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction LYN;ADRA1D;ADRA1B;ADRA1A;SRC;BCR;MAP2K1 GO:0042493| response to drug ADRA1A;SRC;ABCB1;LYN GO:0007275| multicellular organismal development ADRA1D;CAMK2G;CDK2;ADRA1B GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;ADRA1A;BCR;ADRA1B GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;ADRA1D 3764:[DB06616 DB00991] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;LYN;CDK2;HCK GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0006954| inflammatory response PTGS1;HCK;PTGS2;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 3765:[DB06616 DB03003] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03003|Glutathione Sulfonic Acid gstA;GSTM4;GSTA1;GSTP1 common genes common pathways GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1;GSTP1 GO:0043200| response to amino acid stimulus LYN;GSTP1 GO:0009636| response to toxin LYN;GSTP1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;GSTP1;MAP2K1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0007417| central nervous system development GSTP1;SRC;LYN GO:0032869| cellular response to insulin stimulus SRC;GSTP1 GO:0031667| response to nutrient levels GSTP1;SRC GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK GO:0071222| cellular response to lipopolysaccharide GSTP1;SRC;BCR;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0034599| cellular response to oxidative stress ABL1;GSTP1 3766:[DB06616 DB02750] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways GO:0050900| leukocyte migration SLC7A5;SRC;LYN;SLC7A8 GO:0007275| multicellular organismal development CDK2;CAMK2G;SLC7A5 GO:0007399| nervous system development CAMK2G;SLC7A5 GO:0009636| response to toxin SLC7A8;LYN GO:0006810| transport SLC7A5;ABCB1;SLC7A8 GO:0030154| cell differentiation SLC7A5;HCK;CAMK2G 3767:[DB06616 DB11638] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0050715| positive regulation of cytokine secretion SRC;GAPDH GO:1900034| CAMK2G;HSPA8 GO:0006979| response to oxidative stress PRDX1;ABL1 GO:1900026| FLNA;ABL1 GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;NPM1 GO:0070989| oxidative demethylation FTO;CYP3A4;CYP2C8;CYP2D6 GO:0002376| immune system process LYN;HCK;SRC;SFPQ GO:0007165| signal transduction HNRNPK;LYN;NPM1;CLIC1;IQGAP1;DPYSL2;LGALS1;SRC;ZYX;BCR;MAP2K1 GO:0007420| brain development BCR;HNRNPD;DPYSL2 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;UGT1A9;CYP3A4 GO:0097267| CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;UGT2B7;CYP2C8;CYP2C19;CYP2D6 GO:0043547| positive regulation of GTPase activity BCR;IQGAP1 GO:0098609| MYH9;DSP;ANXA2;SRC GO:0031295| T cell costimulation LGALS1;SRC;LYN GO:0016310| phosphorylation CAMK2G;PGK1;CDK2;LYN;MAP3K2;ABL1;PKM;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0036120| IQGAP1;SRC GO:0030168| platelet activation SRC;FLNA;LYN GO:0043149| stress fiber assembly SRC;ZYX GO:0001843| neural tube closure ABL1;PFN1 GO:0036035| osteoclast development SRC;ANXA2 GO:0007229| integrin-mediated signaling pathway ZYX;SRC;HCK;ABL1;MYH9 GO:0032869| cellular response to insulin stimulus PKM;SRC GO:0071456| cellular response to hypoxia SRC;P4HB;HP1BP3;NPEPPS;PGK1 GO:0030154| cell differentiation HCK;DPYSL2;CAMK2G GO:1903800| MAP2K2;MAP2K1;DDX5 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CFL1;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0034614| cellular response to reactive oxygen species SRC;TPM1 GO:0006928| cellular component movement TPM1;TUBB;VIM;HSPB1;ACTG1;MAP2K1 GO:0010628| positive regulation of gene expression VIM;HNRNPD;MAP2K1;SRC GO:0030336| negative regulation of cell migration TPM1;BCR GO:0045892| negative regulation of transcription, DNA-dependent SRC;ENO1;SFPQ;HSPA8 GO:0010033| response to organic substance PKM;CDK2 GO:0008285| negative regulation of cell proliferation NPM1;LYN;MAP2K1 GO:0007411| axon guidance SRC;DPYSL2 GO:0048013| ephrin receptor signaling pathway LYN;ACTG1;SRC GO:0043406| positive regulation of MAP kinase activity SRC;IQGAP1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0014070| response to organic cyclic compound G6PD;LDHA;LYN GO:0006470| protein dephosphorylation CYCS;CAMK2G GO:0043200| response to amino acid stimulus LYN;CFL1 GO:0051496| positive regulation of stress fiber assembly ABL1;TPM1 GO:0030216| keratinocyte differentiation DSP;MAP2K1 GO:0008283| cell proliferation RPL23A;PRDX1;SRC GO:0031175| neuron projection development LYN;MAP4 GO:2000378| negative regulation of reactive oxygen species metabolic process G6PD;BCR GO:0007179| transforming growth factor beta receptor signaling pathway SRC;ZYX GO:0006915| apoptotic process LGALS1;ABL1;CYCS;GAPDH GO:0032872| regulation of stress-activated MAPK cascade PRDX1;MAP2K2;MAP2K1 GO:0045184| establishment of protein localization ABL1;FLNA GO:0045785| positive regulation of cell adhesion SRC;TPM1 GO:0032868| response to insulin stimulus LYN;SRSF4;PKM GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1;HSPB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;TUBB4A;TUBA1A;TUBB GO:0051272| positive regulation of cellular component movement LYN;RPS19 GO:0043066| negative regulation of apoptotic process RPL10;ALB;SRC;RPS6;HCK;FLNA;CFL1;HNRNPK;NPM1;HSPB1 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;ACTG1;HSPB1 GO:0035556| intracellular signal transduction HSPB1;LYN;CAMK2G;BCR;SRC GO:0006897| endocytosis ABL1;DPYSL2 GO:0006805| xenobiotic metabolic process UGT1A9;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0030520| intracellular estrogen receptor signaling pathway SRC;DDX5 GO:0071732| cellular response to nitric oxide CDK2;HNRNPD GO:0008284| positive regulation of cell proliferation RPS9;HCK;NPM1;LYN;CDK2;SHMT2 GO:0009615| response to virus HSPB1;CFL1;SRC;ENO1 GO:0042542| response to hydrogen peroxide SRC;LDHA GO:0051726| regulation of cell cycle HSPA8;BCR;SRC;SFPQ;ABL1;CLIC1 GO:0043065| positive regulation of apoptotic process LDHA;ABL1;SRC;RPS6 GO:0002576| platelet degranulation FLNA;TAGLN2;LYN;ALDOA;ALB GO:0050727| regulation of inflammatory response ZYX;HCK;LYN GO:0006974| response to DNA damage stimulus ABL1;SFPQ;LYN;CDK2;FTO GO:0006281| DNA repair ABL1;SFPQ;FTO;NPM1;CDK2 GO:0006629| lipid metabolic process CYP2D6;UGT2B7;G6PD;CYP3A4 GO:0042981| regulation of apoptotic process LGALS1;MAP2K2;MAP2K1;MAP3K2 GO:0007399| nervous system development CAMK2G;DPYSL2 GO:0008360| regulation of cell shape ALDOA;TPM1;MYH9;HCK GO:0010634| positive regulation of epithelial cell migration SRC;PFN1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HNRNPA2B1;CDK2;DDX5;ENO1;RPL10;SFPQ GO:0007155| cell adhesion MYH9;ABL1;HCK;ZYX;SRC GO:0045087| innate immune response LYN;HCK;SRC;ABL1;SFPQ GO:0051894| positive regulation of focal adhesion assembly ABL1;IQGAP1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;IQGAP1;ABL1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0030838| positive regulation of actin filament polymerization HCK;PFN1 GO:0042127| regulation of cell proliferation ABL1;SRC;HP1BP3 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0030516| regulation of axon extension ABL1;DPYSL2 GO:0001932| regulation of protein phosphorylation HSPB1;LYN;MAP2K1 GO:0048678| response to axon injury LGALS1;LYN GO:0051259| protein oligomerization NPM1;CAMK2G GO:0007275| multicellular organismal development TPI1;CAMK2G;CDK2;RPL10;DPYSL2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LGALS1;ABL1;FLNA GO:0034599| cellular response to oxidative stress ABL1;PRDX1;G6PD;CYCS;P4HB GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:2000573| positive regulation of DNA biosynthetic process DDX39B;SRC GO:0051301| cell division CDK2;TUBA1A;TUBB;MAP4 GO:0051602| response to electrical stimulus SRC;HNRNPD GO:0016032| viral reproduction VIM;HSPA8;NPM1;PPIA;HNRNPK;LYN;SRC;ZYX;HCK GO:0030218| erythrocyte differentiation LYN;RPS19 GO:0000082| G1/S transition of mitotic cell cycle CAMK2G;CDK2;RPS6 GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB4A;CDK2;TUBB;TUBA1A GO:0001817| regulation of cytokine production LYN;IQGAP1 GO:0030036| actin cytoskeleton organization ABL1;BCR;PFN1;CFL1 GO:0060020| Bergmann glial cell differentiation VIM;MAP2K1;ABL1 GO:0038096| LYN;ABL1;ACTG1;HCK;SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;IQGAP1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent HNRNPD;MAP2K1;MAP2K2;SRC;CDK2;NPM1;MAP3K2 GO:0010506| regulation of autophagy ABL1;HSPB1 GO:0006355| regulation of transcription, DNA-dependent HSPA8;HP1BP3;DDX5;HNRNPK;EEF1A1;SF1;ENO1;HNRNPD;SFPQ;ABL1;KHSRP GO:0042493| response to drug LDHA;SRP14;LYN;LGALS1;SRC;ABCB1;HNRNPD GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0010629| negative regulation of gene expression MAP2K1;HNRNPD;MAP2K2 GO:0034332| adherens junction organization DSP;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;ANXA2;LYN GO:0055114| oxidation-reduction process LDHA;P4HB;MDH1;FTO;GAPDH;CYP3A4;CYCS;GAPDHS;LDHB;PRDX1;G6PD;CYP2C8;CYP2C19;CYP2D6;ALDH7A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPI GO:0000278| mitotic cell cycle RPS6;ABL1 GO:0050900| leukocyte migration SRC;PPIA;MYH9;LYN GO:0008209| androgen metabolic process UGT2B7;CYP3A4 3768:[DB06616 DB01161] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;CHRNA10;MAP2K1;HTR3A GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;ABL1 GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SCN10A GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0042472| inner ear morphogenesis BCR;CHRNA10 GO:0042127| regulation of cell proliferation CHRNA10;SRC;ABL1 GO:0006816| calcium ion transport CHRNA10;CAMK2G;GRIN3A GO:0042493| response to drug SLC6A3;SRC;ABCB1;LYN;BCHE 3769:[DB06616 DB01870] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01870|1,4-dithio-alpha-D-glucopyranose AMY2B common genes common pathways 3770:[DB06616 DB07374] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0008283| cell proliferation RPL23A;SRC GO:0010628| positive regulation of gene expression RPL23;RPL11;MAP2K1;SRC GO:1901796| RPL11;CDK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;RPL23 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RPL23 3771:[DB06616 DB04882] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04882|Edotecarin TOP1 common genes common pathways GO:0042493| response to drug SRC;ABCB1;TOP1;LYN GO:0006260| DNA replication TOP1;CDK2 GO:0016032| viral reproduction SRC;HCK;TOP1;LYN GO:0018105| peptidyl-serine phosphorylation TOP1;CDK2;CAMK2G;SRC GO:0016310| phosphorylation TOP1;MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 3772:[DB06616 DB14637] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14637|Fluprednisolone acetate CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 3773:[DB06616 DB06451] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06451|Aprinocarsen PRKCA common genes common pathways GO:0038128| PRKCA;SRC GO:0090330| regulation of platelet aggregation PRKCA;LYN GO:0045931| positive regulation of mitotic cell cycle PRKCA;ABL1 GO:0007155| cell adhesion SRC;HCK;ABL1;PRKCA GO:0035556| intracellular signal transduction LYN;CAMK2G;PRKCA;SRC;BCR GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;PRKCA;SRC GO:0006915| apoptotic process PRKCA;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;PRKCA;MAP2K1;SRC;MAP2K2 GO:0045785| positive regulation of cell adhesion PRKCA;SRC GO:0007411| axon guidance SRC;PRKCA GO:0030168| platelet activation LYN;SRC;PRKCA GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;PRKCA;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0030335| positive regulation of cell migration LYN;PRKCA GO:0016310| phosphorylation PRKCA;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0010595| positive regulation of endothelial cell migration ABL1;PRKCA GO:0070555| response to interleukin-1 PRKCA;SRC 3774:[DB06616 DB00228] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0002376| immune system process KCNN4;LYN;HCK;SRC GO:0006813| potassium ion transport KCNA1;CDK2;KCNN4 GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0007165| signal transduction SRC;BCR;GRIA1;MAP2K1;ATP2C1;GABRB3;GABRE;GABRQ;GABRB1;GABRA5;GABRD;GABRA6;LYN;GABRP GO:0007420| brain development GABRA5;BCR;KCNA1 GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0045332| phospholipid translocation ABCB1;KCNN4 GO:0006810| transport ABCB1;GABRB3;GABRA3;GABRA5;GABRG2;GABRB1;GABRA1;GABRD;GABRB2;GABRA4;GABRA6 GO:0009791| post-embryonic development ABL1;GABRG2 GO:0009636| response to toxin GABRB1;LYN GO:0043200| response to amino acid stimulus GLRB;LYN GO:0055085| transmembrane transport KCNA1;ABCB1 GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0007399| nervous system development GLRB;CAMK2G GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ATP2C1 GO:0006816| calcium ion transport ATP2C1;CAMK2G;KCNN4 GO:0042493| response to drug LYN;CYP2E1;GABRG3;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 3775:[DB06616 DB07207] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC;F3 GO:0031667| response to nutrient levels F7;SRC GO:0051897| positive regulation of protein kinase B signaling cascade F7;SRC;F3 GO:0019221| cytokine-mediated signaling pathway F3;HCK GO:0030335| positive regulation of cell migration F7;LYN;F3 GO:0009725| response to hormone stimulus F7;LYN GO:0014070| response to organic cyclic compound LYN;F7 GO:0007596| blood coagulation F3;LYN;F7 3776:[DB06616 DB08547] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08547|PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0050853| B cell receptor signaling pathway LYN;IGHG2;ABL1 GO:0002376| immune system process IGHG2;LYN;HCK;SRC GO:0038096| LYN;IGHG2;ABL1;SRC;HCK GO:0002250| adaptive immune response IGHG2;LYN GO:0045087| innate immune response ABL1;HCK;SRC;LYN;IGHG2 3777:[DB06616 DB07488] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07488|{(2Z)-4-AMINO-2-[(4-METHOXYPHENYL)IMINO]-2,3-DIHYDRO-1,3-THIAZOL-5-YL}(4-METHOXYPHENYL)METHANONE CSNK1G3 common genes common pathways GO:0008360| regulation of cell shape CSNK1G3;HCK GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC;CSNK1G3 GO:0006897| endocytosis ABL1;CSNK1G3 GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;CSNK1G3 GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;CSNK1G3 GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;CSNK1G3;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0006464| protein modification process CSNK1G3;ABL1 3778:[DB06616 DB07922] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07922|N-oxo-2-(phenylsulfonylamino)ethanamide MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;CDK2 GO:0010628| positive regulation of gene expression MMP12;SRC;MAP2K1 3779:[DB06616 DB00663] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0006915| apoptotic process ABL1;NR3C1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;NR3C1 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0051301| cell division NR3C1;CDK2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 3780:[DB06616 DB00801] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0009791| post-embryonic development ABL1;GABRG2 GO:0009636| response to toxin LYN;GABRB1 GO:0007165| signal transduction GABRQ;GABRB1;GABRA5;GABRE;GABRR2;LYN;GABRP;GABRD;GABRA6;MAP2K1;SRC;BCR;GABRB3 GO:0007420| brain development BCR;GABRA5 GO:0006810| transport GABRA1;GABRB2;GABRD;GABRA6;GABRR1;GABRA4;GABRA3;GABRA5;GABRB1;GABRG2;GABRR2;GABRB3;ABCB1 GO:0007417| central nervous system development SRC;GABRA4;LYN GO:0042493| response to drug LYN;ABCB1;SRC;GABRG3 3781:[DB06616 DB01282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01282|Carbetocin OXTR common genes common pathways GO:0007507| heart development OXTR;MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;OXTR GO:0042493| response to drug LYN;OXTR;SRC;ABCB1 GO:0007165| signal transduction LYN;OXTR;MAP2K1;BCR;SRC GO:0043434| response to peptide hormone stimulus LYN;OXTR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OXTR GO:0014070| response to organic cyclic compound LYN;OXTR 3782:[DB06616 DB01143] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways GO:0032496| response to lipopolysaccharide BCR;ALPL GO:0032869| cellular response to insulin stimulus ENPP1;SRC 3783:[DB06616 DB02715] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02715|Compound 18 ESR1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction LYN;ESR1;MAP2K1;BCR;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 3784:[DB06616 DB00226] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0042493| response to drug LYN;SLC6A2;ABCB1;SRC GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCB1 3785:[DB06616 DB01373] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0030218| erythrocyte differentiation BMP4;LYN GO:0000165| MAPKKK cascade CALM1;MAP2K1;MAP2K2;SPTBN1;CAMK2G GO:0031954| positive regulation of protein autophosphorylation CALM1;SRC GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1;BMP4 GO:0006816| calcium ion transport CAMK2G;ATP2C1;CACNA1C GO:0051602| response to electrical stimulus S100A13;SRC GO:0006954| inflammatory response LYN;S100A8;S100A9;HCK GO:0006914| autophagy S100A9;S100A8;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;BMP4;LYN GO:0055114| oxidation-reduction process CYP2C8;CP;CYP3A4;AOC1 GO:0060425| lung morphogenesis MAP2K1;BMP4 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;BMP4;MAP2K1;SRC;MAP2K2 GO:0060440| trachea formation BMP4;MAP2K1 GO:1900042| SPTBN1;ABL1 GO:0042493| response to drug AOC1;LYN;SRC;ABCB1 GO:0010629| negative regulation of gene expression BMP4;MAP2K2;MAP2K1 GO:0007399| nervous system development CAMK2G;PCDH19 GO:0008360| regulation of cell shape HCK;S100B;S100A13 GO:0045597| positive regulation of cell differentiation BMP4;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;BMP4 GO:0045087| innate immune response S100A8;S100A9;LYN;SRC;HCK;S100B;ABL1 GO:0007155| cell adhesion HCK;SRC;COMP;ABL1;PCDH19 GO:0007507| heart development MAP2K1;CACNA1C;BMP4 GO:0043066| negative regulation of apoptotic process HCK;SRC;COMP;BMP4 GO:0006805| xenobiotic metabolic process CYP3A4;AOC1;CYP2C8 GO:0006935| chemotaxis S100A9;S100A8;MAP2K1 GO:0008284| positive regulation of cell proliferation HCK;S100B;S100A13;BMP4;CDK2;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;S100B;BMP4 GO:0002576| platelet degranulation LYN;CALM1 GO:0050727| regulation of inflammatory response HCK;LYN;S100A9;S100A8 GO:0043542| endothelial cell migration ABL1;S100A2 GO:0007275| multicellular organismal development MGP;CAMK2G;BMP4;CDK2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;ATP2C1;ABL1;S100A13 GO:0032496| response to lipopolysaccharide BCR;S100A8 GO:0045892| negative regulation of transcription, DNA-dependent BMP4;SRC GO:0008285| negative regulation of cell proliferation BMP4;LYN;MAP2K1 GO:0043407| negative regulation of MAP kinase activity LYN;BMP4 GO:0007411| axon guidance SRC;SPTBN1 GO:0010628| positive regulation of gene expression BMP4;MAP2K1;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity CALM1;SRC;MAP2K2;MAP2K1 GO:0009791| post-embryonic development ABL1;BMP4 GO:0006915| apoptotic process S100A9;S100A8;COMP;ABL1;PDCD6 GO:0055085| transmembrane transport CALM1;CACNA1C;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;BMP4 GO:0050663| cytokine secretion S100A13;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;BMP4 GO:0038095| LYN;CALM1 GO:0008283| cell proliferation S100B;SRC GO:0065009| regulation of molecular function CAMK2G;SPTBN1 GO:0030900| forebrain development BMP4;SRC GO:0003014| renal system process BMP4;BCR GO:0007420| brain development BCR;PCDH19 GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;ATP2C1 GO:0002376| immune system process HCK;SRC;S100A9;S100A8;LYN GO:0000186| activation of MAPKK activity MAP3K2;BMP4 GO:0001843| neural tube closure BMP4;ABL1 GO:0071456| cellular response to hypoxia SRC;S100B GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CACNA1C GO:0030154| cell differentiation CAMK2G;MGP;BMP4;HCK GO:1903800| BMP4;MAP2K2;MAP2K1 GO:0034605| cellular response to heat PDCD6;LYN GO:0030335| positive regulation of cell migration LYN;BMP4 GO:0007417| central nervous system development SRC;S100B;LYN GO:0010595| positive regulation of endothelial cell migration BMP4;ABL1;PDCD6 3786:[DB06616 DB01915] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01915|S-Hydroxycysteine C3;GSTP1;ACAT2;GSTA1;PMP2 common genes common pathways GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;ABL1;LYN GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0009636| response to toxin GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;GSTP1;MAP2K2 GO:0050766| positive regulation of phagocytosis BCR;C3 GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0007417| central nervous system development SRC;GSTP1;LYN GO:0032869| cellular response to insulin stimulus GSTP1;SRC GO:0002376| immune system process SRC;HCK;C3;LYN GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0007165| signal transduction LYN;C3;BCR;SRC;MAP2K1 GO:0031667| response to nutrient levels GSTP1;SRC GO:0014003| oligodendrocyte development GSTP1;LYN GO:0001934| positive regulation of protein phosphorylation C3;LYN;ABL1 GO:0006954| inflammatory response LYN;C3;HCK GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0034599| cellular response to oxidative stress GSTP1;ABL1 GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK GO:0071222| cellular response to lipopolysaccharide BCR;SRC;GSTP1;ABL1 GO:0006629| lipid metabolic process ACAT2;CYP3A4;C3 GO:0045087| innate immune response LYN;C3;ABL1;HCK;SRC 3787:[DB06616 DB07593] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07593|1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 3788:[DB06616 DB08361] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways GO:0035556| intracellular signal transduction SYK;LYN;CAMK2G;SRC;BCR GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;SYK;CDK2 GO:0045087| innate immune response HCK;SRC;ABL1;SYK;LYN GO:0018108| peptidyl-tyrosine phosphorylation LYN;SYK;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;SYK GO:0016032| viral reproduction HCK;SRC;SYK;LYN GO:0090330| regulation of platelet aggregation LYN;SYK GO:0006954| inflammatory response SYK;LYN;HCK GO:0002250| adaptive immune response LYN;SYK GO:0038096| LYN;SYK;ABL1;SRC;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SYK;SRC;ABL1 GO:0038083| SRC;HCK;ABL1;SYK;LYN GO:0050715| positive regulation of cytokine secretion SYK;SRC GO:0002376| immune system process SRC;HCK;LYN;SYK GO:0051090| regulation of sequence-specific DNA binding transcription factor activity SYK;HCK GO:0070372| regulation of ERK1 and ERK2 cascade SYK;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway SYK;LYN;HCK GO:0050764| regulation of phagocytosis HCK;SYK GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SYK;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0030168| platelet activation SRC;LYN;SYK GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;SYK;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0007229| integrin-mediated signaling pathway SYK;HCK;SRC;ABL1 GO:0050853| B cell receptor signaling pathway ABL1;SYK;LYN GO:0046777| protein autophosphorylation CAMK2G;SYK;LYN;ABL1;SRC;BCR;HCK GO:0038095| SYK;LYN GO:0008283| cell proliferation SRC;SYK GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;SYK;MAP3K2 GO:0007257| activation of JUN kinase activity SYK;MAP3K2 3789:[DB06616 DB11136] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11136|Chromium CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYB5A GO:0002576| platelet degranulation LYN;TF 3790:[DB06616 DB07159] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07159|Tamatinib SYK common genes common pathways GO:0038096| SYK;LYN;ABL1;HCK;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;SYK GO:0002250| adaptive immune response LYN;SYK GO:0090330| regulation of platelet aggregation SYK;LYN GO:0006954| inflammatory response LYN;SYK;HCK GO:0016032| viral reproduction HCK;SRC;SYK;LYN GO:0038083| ABL1;HCK;SRC;LYN;SYK GO:0045087| innate immune response LYN;SYK;ABL1;HCK;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;SYK GO:0035556| intracellular signal transduction BCR;SRC;SYK;LYN;CAMK2G GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;SYK GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;SYK;LYN GO:0050853| B cell receptor signaling pathway SYK;LYN;ABL1 GO:0046777| protein autophosphorylation LYN;SYK;CAMK2G;ABL1;HCK;BCR;SRC GO:0007257| activation of JUN kinase activity SYK;MAP3K2 GO:0000187| activation of MAPK activity MAP3K2;SYK;MAP2K1;MAP2K2 GO:0008283| cell proliferation SYK;SRC GO:0038095| SYK;LYN GO:0051090| regulation of sequence-specific DNA binding transcription factor activity SYK;HCK GO:0070372| regulation of ERK1 and ERK2 cascade LYN;SYK GO:0002376| immune system process HCK;SRC;LYN;SYK GO:0050715| positive regulation of cytokine secretion SYK;SRC GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2;SYK GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK;SYK GO:0030168| platelet activation SRC;SYK;LYN GO:0016310| phosphorylation MAP3K2;CAMK2G;SYK;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0050764| regulation of phagocytosis SYK;HCK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;SYK 3791:[DB06616 DB09209] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;SRC;MAP2K2;MAP2K1;ABL1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0007165| signal transduction OPRK1;SRC;BCR;MAP2K1;LYN;OPRM1;OPRD1 GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0010629| negative regulation of gene expression OPRD1;MAP2K2;MAP2K1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;OPRK1;ABL1 GO:0032496| response to lipopolysaccharide OPRM1;BCR 3792:[DB06616 DB00114] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0006979| response to oxidative stress ABL1;TAT GO:0007420| brain development SRR;BCR GO:0030097| hemopoiesis LYN;SGPL1 GO:0030154| cell differentiation IGSF10;CAMK2G;HCK GO:0032869| cellular response to insulin stimulus GOT1;SRC GO:0009791| post-embryonic development ABL1;SGPL1 GO:0008283| cell proliferation SRC;BCAT1 GO:0006470| protein dephosphorylation PDXP;CAMK2G GO:0009636| response to toxin DDC;LYN GO:0014070| response to organic cyclic compound TAT;LYN;SRR GO:0006915| apoptotic process SGPL1;ABL1 GO:0009615| response to virus ODC1;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;SHMT2;HCK;ODC1 GO:0043066| negative regulation of apoptotic process SRC;HCK;CTH GO:0006629| lipid metabolic process SPTLC3;SPTLC2;CYP3A4;SGPL1;SPTLC1 GO:0032496| response to lipopolysaccharide BCR;SRR GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;SGPL1;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;ABL1 GO:0007275| multicellular organismal development CDK2;CAMK2G;IGSF10 GO:0000082| G1/S transition of mitotic cell cycle BCAT1;CDK2;CAMK2G GO:0030218| erythrocyte differentiation LYN;ALAS2 GO:0042493| response to drug LYN;GAD2;GAD1;ABAT;SRR;SRC;ABCB1 GO:0008209| androgen metabolic process CYP3A4;SGPL1 GO:0055114| oxidation-reduction process CBS;CYP3A4;GLDC;PNPO;CYP2C8 3793:[DB06616 DB02931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways GO:0032868| response to insulin stimulus LYN;AANAT GO:0014070| response to organic cyclic compound AANAT;LYN 3794:[DB06616 DB05513] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05513|Atiprimod IL6;TNF common genes common pathways GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0051222| positive regulation of protein transport SRC;TNF GO:0030168| platelet activation LYN;SRC;IL6 GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0010628| positive regulation of gene expression TNF;MAP2K1;IL6;SRC GO:0008285| negative regulation of cell proliferation LYN;IL6;MAP2K1 GO:0010033| response to organic substance TNF;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0070301| cellular response to hydrogen peroxide ABL1;IL6 GO:0031175| neuron projection development IL6;LYN GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0000187| activation of MAPK activity MAP3K2;TNF;MAP2K1;MAP2K2 GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ABL1;MAP2K2;SRC;MAP2K1 GO:0043066| negative regulation of apoptotic process SRC;IL6;HCK GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;LYN;HCK GO:0043065| positive regulation of apoptotic process SRC;IL6;ABL1;TNF GO:0050727| regulation of inflammatory response LYN;TNF;HCK GO:0008284| positive regulation of cell proliferation HCK;IL6;CDK2;LYN GO:0009615| response to virus SRC;TNF GO:0071222| cellular response to lipopolysaccharide TNF;BCR;SRC;IL6;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TNF GO:0042127| regulation of cell proliferation TNF;SRC;ABL1 GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0007275| multicellular organismal development CAMK2G;CDK2;TNF GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL6;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0006954| inflammatory response LYN;TNF;HCK;IL6 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0019221| cytokine-mediated signaling pathway IL6;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;IL6 GO:0045893| positive regulation of transcription, DNA-dependent TNF;CDK2;MAP3K2;MAP2K2;SRC;MAP2K1;IL6 GO:0010629| negative regulation of gene expression TNF;MAP2K2;MAP2K1 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;TNF GO:0050900| leukocyte migration LYN;TNF;SRC 3795:[DB06616 DB11091] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0070542| response to fatty acid CAT;SRC GO:0006979| response to oxidative stress ABL1;CAT;GPX1 GO:0032868| response to insulin stimulus CAT;LYN GO:0006915| apoptotic process ABL1;GPX1 GO:0008283| cell proliferation SRC;GPX1 GO:0009636| response to toxin LYN;GPX1;CAT GO:0034599| cellular response to oxidative stress ABL1;CAT;GPX1 GO:0006629| lipid metabolic process GPX1;CYP3A4 GO:0042542| response to hydrogen peroxide CAT;SRC;GPX1 GO:0043066| negative regulation of apoptotic process CAT;HCK;SRC;GPX1 GO:0055114| oxidation-reduction process GPX1;CYP2C8;CAT;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC GO:0042493| response to drug SRC;ABCB1;CAT;LYN GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC 3796:[DB06616 DB13153] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 3797:[DB06616 DB08340] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08340|N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE CSNK2A1 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CSNK2A1 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;CSNK2A1;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2;CSNK2A1 GO:0007049| cell cycle SRC;CDK2;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CSNK2A1;MAP2K1 GO:0006915| apoptotic process CSNK2A1;ABL1 GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0016236| macroautophagy CSNK2A1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC 3798:[DB06616 DB11640] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0007420| brain development BCR;KCNA1 GO:0006813| potassium ion transport CDK2;KCNA1 GO:0055085| transmembrane transport ABCB1;KCNA1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;NAT2;NAT1 3799:[DB06616 DB08270] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08270|N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 3800:[DB06616 DB02860] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02860|Calyculin A PPP1CC common genes common pathways GO:0007049| cell cycle CDK2;SRC;PPP1CC GO:0030182| neuron differentiation MAP2K1;ABL1;PPP1CC GO:0006470| protein dephosphorylation CAMK2G;PPP1CC GO:0051301| cell division PPP1CC;CDK2 3801:[DB06616 DB00020] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00020|Sargramostim CSF2RA;IL3RA;CSF2RB;SDC2;PRG2 common genes common pathways GO:0002376| immune system process PRG2;SRC;HCK;LYN GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CSF2RB GO:0065009| regulation of molecular function CAMK2G;CSF2RB;CSF2RA;IL3RA GO:0030154| cell differentiation HCK;CAMK2G;SDC2 GO:0048013| ephrin receptor signaling pathway LYN;SDC2;SRC GO:0016477| cell migration SRC;SDC2 GO:0007399| nervous system development CAMK2G;SDC2 GO:0032496| response to lipopolysaccharide CSF2RB;BCR GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;MAP2K2;CSF2RA;BCR;HCK;MAP2K1;IL3RA;CSF2RB;LYN GO:0019221| cytokine-mediated signaling pathway CSF2RB;CSF2RA;IL3RA;HCK GO:0000165| MAPKKK cascade CAMK2G;CSF2RB;IL3RA;MAP2K1;MAP2K2;CSF2RA GO:0050900| leukocyte migration SRC;SDC2;LYN 3802:[DB06616 DB03193] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes common pathways GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0007507| heart development PPARA;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;CDK2 GO:0006629| lipid metabolic process PPARA;CYP3A4;PLA2G2D GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARA GO:0042493| response to drug LYN;FABP3;ABCB1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;PPARA;MAP3K2 GO:0006954| inflammatory response HCK;LYN;PLA2G2D GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0070542| response to fatty acid SRC;FABP3 GO:0032868| response to insulin stimulus FABP3;LYN;PPARA GO:0008285| negative regulation of cell proliferation FABP3;MAP2K1;LYN 3803:[DB06616 DB02258] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02258|SR11254 RARG common genes common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1;RARG GO:0008285| negative regulation of cell proliferation MAP2K1;RARG;LYN GO:0001843| neural tube closure RARG;ABL1 GO:0006355| regulation of transcription, DNA-dependent RARG;ABL1 GO:0060324| face development RARG;MAP2K1 GO:0071300| cellular response to retinoic acid RARG;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;RARG GO:0043065| positive regulation of apoptotic process RARG;ABL1;SRC GO:0008284| positive regulation of cell proliferation HCK;RARG;LYN;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARG 3804:[DB06616 DB11569] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11569|Ixekizumab IL17A common genes common pathways GO:0006954| inflammatory response HCK;LYN;IL17A GO:0006915| apoptotic process ABL1;IL17A 3805:[DB06616 DB06345] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06345|AR-9281 EPHX2 common genes common pathways GO:0009636| response to toxin LYN;EPHX2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;EPHX2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;EPHX2 GO:0006954| inflammatory response LYN;EPHX2;HCK GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;EPHX2;CYP3A4 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 3806:[DB06616 DB08738] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08738|1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one PREP common genes common pathways 3807:[DB06616 DB01130] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;BCR;SRC;NR3C1;LYN GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0042359| vitamin D metabolic process CYP3A4 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006915| apoptotic process NR3C1;ABL1 GO:0036378| CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0051301| cell division CDK2;NR3C1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 3808:[DB06616 DB06151] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0050900| leukocyte migration SRC;LYN;SLC7A11 GO:0031667| response to nutrient levels GSS;SRC GO:0045893| positive regulation of transcription, DNA-dependent IKBKB;CDK2;MAP3K2;SRC;CHUK;MAP2K2;MAP2K1 GO:1901216| ABL1;GRIN2B GO:0042493| response to drug LYN;SRC;CHUK;ABCB1;GRIN2A GO:0000165| MAPKKK cascade GRIN2A;MAP2K2;MAP2K1;GRIN2B;CAMK2G;GRIN1;GRIN2D GO:0006816| calcium ion transport GRIN3A;CAMK2G;GRIN1;GRIN2A GO:0006954| inflammatory response IKBKB;LYN;HCK;CHUK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKB;CHUK;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway CHUK;SRC;IKBKB;LYN GO:0032496| response to lipopolysaccharide CHUK;BCR GO:0007399| nervous system development GSS;CAMK2G GO:0045087| innate immune response ABL1;HCK;CHUK;SRC;LYN;IKBKB GO:0043066| negative regulation of apoptotic process IKBKB;HCK;SRC GO:0006805| xenobiotic metabolic process ACY1;CYP2C8;CYP3A4 GO:0018105| peptidyl-serine phosphorylation SRC;CHUK;CDK2;IKBKB;CAMK2G GO:0009615| response to virus CHUK;SRC;IKBKB GO:0043065| positive regulation of apoptotic process GRIN1;GRIN2A;ABL1;SRC GO:0055085| transmembrane transport SLCO1B1;SLC22A6;ABCB1 GO:0009636| response to toxin CHUK;SLC7A11;LYN GO:0043200| response to amino acid stimulus LYN;CHUK;GSS GO:0038095| LYN;IKBKB;CHUK GO:0010033| response to organic substance CDK2;CHUK GO:0048013| ephrin receptor signaling pathway GRIN1;LYN;GRIN2B;SRC GO:0034614| cellular response to reactive oxygen species CHUK;SRC GO:0006810| transport GRIN2B;GRIN2A;ABCB1 GO:0006468| protein phosphorylation MAP2K2;BCR;CHUK;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2;IKBKB GO:0016310| phosphorylation HCK;MAP2K1;CHUK;SRC;MAP2K2;BCR;ABL1;MAP3K2;IKBKB;CDK2;LYN;CAMK2G GO:0065009| regulation of molecular function GRIN2A;CAMK2G;GRIN2B;GRIN2D;GRIN1 GO:0007420| brain development SLC7A11;BCR GO:0006979| response to oxidative stress ABL1;GSS;SLC7A11 3809:[DB06616 DB07125] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07125|4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid DAPK3 common genes common pathways GO:0010506| regulation of autophagy DAPK3;ABL1 GO:0006355| regulation of transcription, DNA-dependent DAPK3;ABL1 GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K1;MAP2K2;DAPK3 GO:0042981| regulation of apoptotic process DAPK3;MAP2K1;MAP2K2;MAP3K2 GO:0008360| regulation of cell shape HCK;DAPK3 GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;DAPK3 GO:2000145| regulation of cell motility ABL1;DAPK3 GO:2000249| regulation of actin cytoskeleton reorganization DAPK3;ABL1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;DAPK3;SRC GO:0043065| positive regulation of apoptotic process ABL1;DAPK3;SRC GO:0006915| apoptotic process DAPK3;ABL1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1;DAPK3 GO:0030182| neuron differentiation MAP2K1;DAPK3;ABL1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;DAPK3 GO:0046777| protein autophosphorylation ABL1;DAPK3;BCR;SRC;HCK;CAMK2G;LYN GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;DAPK3;ABL1 GO:0030335| positive regulation of cell migration LYN;DAPK3 GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;DAPK3 3810:[DB06616 DB03704] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ADH5;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;ADH5 3811:[DB06616 DB06634] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06634|Casopitant CYP3A4;TACR1 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0007165| signal transduction BCR;SRC;MAP2K1;TACR1;LYN GO:0009725| response to hormone stimulus TACR1;LYN GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TACR1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0051496| positive regulation of stress fiber assembly ABL1;TACR1 GO:0014070| response to organic cyclic compound LYN;TACR1 GO:0036378| CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0010634| positive regulation of epithelial cell migration TACR1;SRC GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006954| inflammatory response LYN;TACR1;HCK GO:0051602| response to electrical stimulus TACR1;SRC GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 3812:[DB06616 DB05024] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0007165| signal transduction SRC;BCR;VDR;MAP2K1;LYN GO:0042359| vitamin D metabolic process CYP3A4;CYP24A1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;VDR GO:0008285| negative regulation of cell proliferation MAP2K1;VDR;LYN GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;CDK2 GO:0007275| multicellular organismal development CDK2;CAMK2G;VDR GO:0006816| calcium ion transport VDR;CAMK2G GO:0006355| regulation of transcription, DNA-dependent ABL1;VDR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP24A1 3813:[DB06616 DB09488] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09488|Acrivastine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;LYN;MAP2K1;SRC;BCR GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0006954| inflammatory response HCK;LYN;HRH1 3814:[DB06616 DB08869] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08869|Tesamorelin GHRHR common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;GHRHR GO:0032869| cellular response to insulin stimulus SRC;GHRHR GO:0032868| response to insulin stimulus GHRHR;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;GHRHR;HCK 3815:[DB06616 DB08676] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08676|(20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0042127| regulation of cell proliferation ABL1;SRC;FNTB GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FNTA 3816:[DB06616 DB03509] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03509|2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide PARP1 common genes common pathways GO:0034599| cellular response to oxidative stress ABL1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0006974| response to DNA damage stimulus ABL1;PARP1;LYN;CDK2 GO:0006281| DNA repair ABL1;CDK2;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 GO:1901216| ABL1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:1900182| PARP1;SRC GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:0006915| apoptotic process PARP1;ABL1 3817:[DB06616 DB07465] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;DPP4;LYN GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;DPP4;HCK GO:0043542| endothelial cell migration DPP4;ABL1 3818:[DB06616 DB03507] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNFRSF1A GO:0006915| apoptotic process TNFRSF1A;ABL1 GO:0007165| signal transduction LYN;MAP2K1;BCR;TNFRSF1A;SRC GO:0016032| viral reproduction LYN;HCK;TNFRSF1A;SRC GO:0006954| inflammatory response LYN;TNFRSF1A;HCK GO:0050728| negative regulation of inflammatory response TNFRSF1A;BCR GO:0019221| cytokine-mediated signaling pathway TNFRSF1A;HCK GO:0032496| response to lipopolysaccharide BCR;TNFRSF1A GO:0042127| regulation of cell proliferation TNFRSF1A;SRC;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;TNFRSF1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFRSF1A;ABL1 GO:0071260| cellular response to mechanical stimulus TNFRSF1A;MAP3K2 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;MAP2K2;TNFRSF1A 3819:[DB06616 DB07662] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07662|N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE SRC;EGFR common genes SRC common pathways GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;EGFR;SRC;BCR;ABL1 GO:0051895| negative regulation of focal adhesion assembly SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0071375| cellular response to peptide hormone stimulus SRC GO:0007411| axon guidance SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0014070| response to organic cyclic compound LYN;EGFR GO:0016477| cell migration SRC GO:0008283| cell proliferation SRC;EGFR GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade EGFR;MAP2K1;SRC;MAP2K2;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0006979| response to oxidative stress EGFR;ABL1 GO:0032463| negative regulation of protein homooligomerization SRC GO:0002376| immune system process SRC;HCK;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0070555| response to interleukin-1 SRC GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;LYN GO:0070542| response to fatty acid SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0007165| signal transduction SRC;BCR;EGFR;MAP2K1;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EGFR;HCK;LYN GO:0030335| positive regulation of cell migration LYN;EGFR GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC;EGFR GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;EGFR;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0036120| SRC GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0000186| activation of MAPKK activity MAP3K2;EGFR GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;EGFR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:1903800| MAP2K1;EGFR;MAP2K2 GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC GO:0071498| cellular response to fluid shear stress SRC GO:0000165| MAPKKK cascade EGFR;MAP2K1;MAP2K2;CAMK2G GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0038128| EGFR;SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0038096| LYN;ABL1;SRC;HCK GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;EGFR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K2;SRC;MAP2K1;EGFR GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0042493| response to drug LYN;ABCB1;SRC GO:0038083| ABL1;EGFR;HCK;SRC;LYN GO:0034332| adherens junction organization SRC GO:0001934| positive regulation of protein phosphorylation ABL1;EGFR;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0050900| leukocyte migration SRC;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;EGFR GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;EGFR;SRC;BCR GO:2000145| regulation of cell motility ABL1;EGFR GO:0071398| cellular response to fatty acid SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;EGFR;HCK GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion ABL1;SRC;HCK GO:0045087| innate immune response LYN;HCK;SRC;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation ABL1;SRC;EGFR GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K1;HCK;EGFR;MAP2K2;BCR;SRC;ABL1 GO:0007275| multicellular organismal development CDK2;CAMK2G;EGFR GO:0086098| SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC 3820:[DB06616 DB06422] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06422|Ticalopride HTR4;HTR3A common genes common pathways GO:0007165| signal transduction HTR3A;MAP2K1;SRC;BCR;LYN;HTR4 3821:[DB06616 DB05869] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways GO:0001932| regulation of protein phosphorylation TNF;LYN;MAP2K1 GO:0042127| regulation of cell proliferation TNF;SRC;ABL1 GO:0007275| multicellular organismal development TNF;CDK2;CAMK2G GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;TNF;HCK GO:0071222| cellular response to lipopolysaccharide TNF;ABL1;BCR;SRC GO:0009615| response to virus TNF;SRC GO:0006935| chemotaxis MAP2K1;HMGB1 GO:0050727| regulation of inflammatory response LYN;TNF;HCK GO:0043065| positive regulation of apoptotic process SRC;HMGB1;ABL1;TNF GO:0006974| response to DNA damage stimulus CDK2;LYN;ABL1;HMGB1 GO:0006281| DNA repair HMGB1;ABL1;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HMGB1;TNF;CDK2 GO:0045087| innate immune response LYN;ABL1;HMGB1;SRC;HCK GO:0045893| positive regulation of transcription, DNA-dependent CDK2;TNF;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0010506| regulation of autophagy HMGB1;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;TNF GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;TNF GO:0006914| autophagy ABL1;HMGB1 GO:0050900| leukocyte migration SRC;TNF;LYN GO:0006954| inflammatory response HMGB1;HCK;TNF;LYN GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0002250| adaptive immune response LYN;HMGB1 GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0000165| MAPKKK cascade TNF;CAMK2G;MAP2K1;MAP2K2 GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration HMGB1;ABL1 GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0002376| immune system process HMGB1;HCK;SRC;LYN GO:0051222| positive regulation of protein transport TNF;SRC GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0031175| neuron projection development LYN;HMGB1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;MAP2K1;SRC;MAP2K2;HMGB1;ABL1 GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0010628| positive regulation of gene expression TNF;SRC;MAP2K1 GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0045892| negative regulation of transcription, DNA-dependent TNF;SRC GO:0010033| response to organic substance TNF;CDK2 GO:0043406| positive regulation of MAP kinase activity TNF;SRC 3822:[DB06616 DB01629] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;SOD1 GO:0042542| response to hydrogen peroxide SOD1;SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1;SOD1 GO:0002576| platelet degranulation SOD1;LYN GO:0048678| response to axon injury LYN;SOD1 GO:0034599| cellular response to oxidative stress ABL1;SOD1 GO:0031667| response to nutrient levels SRC;SOD1 GO:0042493| response to drug SOD1;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;SOD1 GO:0006979| response to oxidative stress ABL1;SOD1 GO:0048538| thymus development ABL1;MAP2K1;SOD1 GO:0010033| response to organic substance CDK2;SOD1 GO:0000187| activation of MAPK activity SOD1;MAP3K2;MAP2K1;MAP2K2 3823:[DB06616 DB12478] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0030900| forebrain development DRD2;SRC GO:0007165| signal transduction DRD3;LYN;SRC;DRD2;BCR;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;DRD2;SRC;MAP2K1 GO:0009636| response to toxin DRD2;LYN GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;LYN GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0048678| response to axon injury LYN;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DRD3 GO:0035556| intracellular signal transduction BCR;SRC;DRD2;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation DRD3;CDK2;LYN;HCK GO:0042493| response to drug DRD3;LYN;DRD2;SRC;ABCB1 3824:[DB06616 DB02936] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02936|4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;PLA2G2A 3825:[DB06616 DB02335] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02335|2-Aminothiazoline NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;NOS3;MAP2K1 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN GO:0043542| endothelial cell migration ABL1;NOS3 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS3 3826:[DB06616 DB07387] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07387|3-(BUTYLSULPHONYL)-PROPANOIC ACID TPI1 common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;TPI1 3827:[DB06616 DB00824] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;ADORA1;LYN;ADORA2A;ADORA3 GO:0030336| negative regulation of cell migration ADORA3;BCR GO:0000187| activation of MAPK activity MAP2K1;ADORA2B;MAP2K2;MAP3K2 GO:0006915| apoptotic process ADORA2A;ABL1 GO:0007596| blood coagulation LYN;ADORA2A GO:0007165| signal transduction ADORA2A;ADORA3;LYN;ADORA1;PDE4A;PDE4B;ADORA2B;MAP2K1;SRC;BCR GO:0000186| activation of MAPKK activity ADORA1;MAP3K2 GO:0007417| central nervous system development LYN;ADORA2A;SRC GO:0031668| cellular response to extracellular stimulus LYN;ADORA2B GO:0051924| regulation of calcium ion transport ADORA2A;CAMK2G GO:0050728| negative regulation of inflammatory response ADORA2A;ADORA1;BCR GO:0006954| inflammatory response HCK;ADORA1;LYN;ADORA3;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;SRC GO:0050900| leukocyte migration LYN;PDE4B;SRC GO:0006909| phagocytosis ADORA1;ADORA2A;ABL1;HCK GO:0042493| response to drug ADORA2A;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;ABL1 GO:0007399| nervous system development CAMK2G;ADORA1 GO:0043066| negative regulation of apoptotic process ADORA1;SRC;HCK GO:0071222| cellular response to lipopolysaccharide BCR;SRC;PDE4B;ABL1 3828:[DB06616 DB11834] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11834|Guselkumab IL23A common genes common pathways GO:0006954| inflammatory response LYN;HCK;IL23A GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL23A GO:0045087| innate immune response HCK;IL23A;SRC;ABL1;LYN GO:0002376| immune system process LYN;SRC;IL23A;HCK 3829:[DB06616 DB02318] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02318|2-deoxy-2-fluoro-alpha-D-mannosyl fluoride MAN2A1 common genes common pathways 3830:[DB06616 DB00848] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways GO:0007399| nervous system development CHRNA3;CAMK2G GO:0007165| signal transduction MAP2K1;SRC;CHRNA3;BCR;LYN 3831:[DB06616 DB04947] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04947|Altropane SLC6A3 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;SLC6A3 GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0014070| response to organic cyclic compound LYN;SLC6A3 3832:[DB06616 DB01860] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 3833:[DB06616 DB04080] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04080|RU78191 SRC common genes SRC common pathways GO:0086098| SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;LYN GO:0042127| regulation of cell proliferation ABL1;SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response LYN;ABL1;HCK;SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN GO:0071398| cellular response to fatty acid SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0050900| leukocyte migration LYN;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0034332| adherens junction organization SRC GO:0042493| response to drug LYN;SRC;ABCB1 GO:0038083| HCK;SRC;ABL1;LYN GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0038096| ABL1;HCK;SRC;LYN GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0038128| SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0071456| cellular response to hypoxia SRC GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0036120| SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0043406| positive regulation of MAP kinase activity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0007411| axon guidance SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle CDK2;SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation ABL1;HCK;SRC;BCR;LYN;CAMK2G GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0034614| cellular response to reactive oxygen species SRC 3834:[DB06616 DB02917] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;HDAC8 GO:0010629| negative regulation of gene expression HDAC8;MAP2K2;MAP2K1 3835:[DB06616 DB11124] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction ADRA2C;ADRB2;ADRA2B;LYN;ADRA1D;ADRA2A;ADRA1B;ADRB3;ADRB1;ADRA1A;SRC;BCR;MAP2K1 GO:0045453| bone resorption SRC;ADRB2 GO:0030168| platelet activation SRC;ADRA2A;LYN;ADRA2B;ADRA2C GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1B;ABL1;ADRA1A GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;ADRB2 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;ADRA2B GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;ADRA1A;SRC;MAP2K2;ABL1 GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;ADRA1A;ADRA1B GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;CDK2;LYN;ADRA1D GO:0007275| multicellular organismal development ADRA1D;CAMK2G;CDK2;ADRA1B GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0042493| response to drug LYN;SRC;ADRA1A;ABCB1 3836:[DB06616 DB02226] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0006260| DNA replication CDK2;ACHE GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0008283| cell proliferation ACHE;SRC 3837:[DB06616 DB09018] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09018|Bromopride DRD2 common genes common pathways GO:0042493| response to drug ABCB1;SRC;DRD2;LYN GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;DRD2;BCR GO:0048678| response to axon injury DRD2;LYN GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;LYN GO:0009636| response to toxin LYN;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;DRD2;MAP2K1 GO:0030900| forebrain development SRC;DRD2 GO:0007165| signal transduction MAP2K1;BCR;DRD2;SRC;LYN 3838:[DB06616 DB01096] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01096|Oxamniquine CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 3839:[DB06616 DB05990] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0002376| immune system process LYN;NR1H4;SRC;HCK GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0007165| signal transduction NR1H4;LYN;BCR;SRC;MAP2K1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0043066| negative regulation of apoptotic process NR1H4;SRC;HCK GO:0071398| cellular response to fatty acid SRC;NR1H4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;NR1H4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;BAAT;CYP1A2 GO:0045087| innate immune response NR1H4;LYN;HCK;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;CDK2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;NR1H4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006954| inflammatory response HCK;NR1H4;LYN GO:0050728| negative regulation of inflammatory response BCR;NR1H4 GO:0046628| positive regulation of insulin receptor signaling pathway NR1H4;SRC GO:0006355| regulation of transcription, DNA-dependent NR1H4;ABL1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 3840:[DB06616 DB06061] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06061|AZD-8330 MAP3K1 common genes common pathways GO:0000165| MAPKKK cascade CAMK2G;MAP3K1;MAP2K1;MAP2K2 GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K1;MAP3K1;MAP2K2 GO:0023014| signal transduction via phosphorylation event MAP3K1;LYN GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;MAP3K1;MAP2K1 GO:0071260| cellular response to mechanical stimulus MAP3K2;MAP3K1 GO:0038095| LYN;MAP3K1 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;MAP3K1;HCK GO:0006468| protein phosphorylation ABL1;MAP2K1;MAP3K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0000186| activation of MAPKK activity MAP3K2;MAP3K1 3841:[DB06616 DB05797] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05797|TNX-901 FCER1A common genes common pathways GO:0038095| FCER1A;LYN 3842:[DB06616 DB07402] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07402|Azapropazone ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0002576| platelet degranulation ALB;LYN 3843:[DB06616 DB04700] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;GSTK1 3844:[DB06616 DB04593] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways GO:0014070| response to organic cyclic compound F7;LYN GO:0007596| blood coagulation F7;LYN GO:0030335| positive regulation of cell migration F7;LYN GO:0009725| response to hormone stimulus F7;LYN GO:0031667| response to nutrient levels SRC;F7 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F7 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC;F7 3845:[DB06616 DB08054] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08054|1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes SRC common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;HCK;ABL1 GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0060491| regulation of cell projection assembly SRC GO:0036120| SRC GO:0007417| central nervous system development SRC;LYN GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0031295| T cell costimulation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0048477| oogenesis SRC GO:0071456| cellular response to hypoxia SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0016032| viral reproduction HCK;SRC;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0071498| cellular response to fluid shear stress SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038096| ABL1;HCK;SRC;LYN GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;MAP2K2;SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0038083| ABL1;SRC;HCK;LYN GO:0042493| response to drug LYN;ABCB1;SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration LYN;SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0045087| innate immune response HCK;SRC;ABL1;LYN GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0042127| regulation of cell proliferation ABL1;SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:0086098| SRC 3846:[DB06616 DB03082] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03082|6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide PLAU common genes common pathways GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007596| blood coagulation PLAU;LYN GO:0007165| signal transduction PLAU;MAP2K1;SRC;BCR;LYN GO:0030335| positive regulation of cell migration PLAU;LYN GO:0006935| chemotaxis PLAU;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC 3847:[DB06616 DB02209] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PNPO;CYP2C8 GO:0009615| response to virus ODC1;SRC GO:0008284| positive regulation of cell proliferation HCK;ODC1;LYN;CDK2 3848:[DB06616 DB05088] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05088|Tiomolibdate ion APP common genes common pathways GO:1900272| ABL1;APP GO:0010628| positive regulation of gene expression SRC;MAP2K1;APP GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;APP GO:0031175| neuron projection development APP;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;SRC;MAP2K2;MAP2K1;ABL1 GO:0006915| apoptotic process APP;ABL1 GO:0000187| activation of MAPK activity MAP3K2;APP;MAP2K2;MAP2K1 GO:0006979| response to oxidative stress ABL1;APP GO:0030900| forebrain development APP;SRC GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2;APP GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;APP GO:0051897| positive regulation of protein kinase B signaling cascade SRC;APP GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;APP GO:1901216| ABL1;APP GO:0050885| neuromuscular process controlling balance APP;BCR;ABL1 GO:0001934| positive regulation of protein phosphorylation APP;LYN;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;APP GO:0002576| platelet degranulation LYN;APP GO:0006897| endocytosis ABL1;APP GO:0042327| positive regulation of phosphorylation LYN;APP GO:0007155| cell adhesion SRC;HCK;ABL1;APP GO:0045087| innate immune response ABL1;SRC;HCK;LYN;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;APP GO:0007399| nervous system development APP;CAMK2G GO:0045931| positive regulation of mitotic cell cycle ABL1;APP GO:0043393| regulation of protein binding SRC;APP 3849:[DB06616 DB09241] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09241|Methylene blue GUCY1A2;NOS1 common genes common pathways GO:0007165| signal transduction LYN;GUCY1A2;BCR;SRC;MAP2K1 GO:0035556| intracellular signal transduction LYN;GUCY1A2;CAMK2G;BCR;SRC GO:0055114| oxidation-reduction process CYP3A4;NOS1;CYP2C8 GO:0042738| exogenous drug catabolic process NOS1;CYP3A4;CYP2C8 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;NOS1;MAP2K1;SRC;MAP2K2 3850:[DB06616 DB04351] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04351|Aconitate Ion ACO2 common genes common pathways 3851:[DB06616 DB08590] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways GO:0045087| innate immune response ABL1;SRC;HCK;LYN;IRAK4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IRAK4;ABL1 GO:0019221| cytokine-mediated signaling pathway HCK;IRAK4 GO:0002376| immune system process IRAK4;LYN;SRC;HCK GO:0007165| signal transduction BCR;SRC;MAP2K1;IRAK4;LYN GO:0016310| phosphorylation MAP3K2;IRAK4;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;IRAK4;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC 3852:[DB06616 DB05749] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05749|MPI-674 CYP19A1 common genes common pathways GO:0060065| uterus development CYP19A1;SRC GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 3853:[DB06616 DB09363] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0009636| response to toxin SLC18A2;LYN;MAOB GO:0055085| transmembrane transport SLC18A2;SLC6A2;ABCB1 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0006810| transport ABCB1;SLC6A2 GO:0042493| response to drug SRC;ABCB1;SLC6A2;MAOB;LYN GO:0055114| oxidation-reduction process MAOA;MAOB;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide BCR;MAOB 3854:[DB06616 DB04888] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;DRD2;SRC;LYN;HTR1A GO:0030900| forebrain development SRC;DRD2 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;LYN GO:0008283| cell proliferation SRC;HTR1A GO:0009636| response to toxin LYN;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;SRC;MAP2K2;MAP2K1;ABL1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR1A GO:0035556| intracellular signal transduction BCR;SRC;DRD2;CAMK2G;LYN GO:0048678| response to axon injury LYN;DRD2 GO:0042493| response to drug LYN;ABCB1;SRC;DRD2 3855:[DB06616 DB01858] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01858|[1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 3856:[DB06616 DB14010] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;HTR2A;HTR1A GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K1;SRC;MAP2K2;ABL1 GO:0008283| cell proliferation SRC;HTR1A GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HTR2A;LYN;CDK2;HTR1A;HCK GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0016032| viral reproduction HTR2A;LYN;HCK;SRC GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0042493| response to drug SRC;ABCB1;LYN;HTR2A 3857:[DB06616 DB00944] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00944|Demecarium ACHE;BCHE common genes common pathways GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0007399| nervous system development CAMK2G;ACHE GO:0042493| response to drug BCHE;LYN;SRC;ABCB1 GO:0006260| DNA replication ACHE;CDK2 GO:0008283| cell proliferation ACHE;SRC GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 3858:[DB06616 DB14509] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:1901216| ABL1;GSK3B GO:0007275| multicellular organismal development GSK3B;CDK2;CAMK2G GO:0007399| nervous system development CAMK2G;GSK3B GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;GSK3B;MAP3K2 GO:0043066| negative regulation of apoptotic process GSK3B;HCK;SRC GO:0035556| intracellular signal transduction SRC;BCR;GSK3B;LYN;CAMK2G GO:0018105| peptidyl-serine phosphorylation SRC;GSK3B;CAMK2G;CDK2 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;GSK3B;MAP2K1 GO:0031175| neuron projection development GSK3B;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;GSK3B GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;GSK3B;BCR;SRC;HCK GO:0006810| transport ABCB1;GRIA3 GO:0030154| cell differentiation HCK;GSK3B;CAMK2G GO:0006468| protein phosphorylation ABL1;GSK3B;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;MAP3K2 GO:0043547| positive regulation of GTPase activity BCR;GSK3B GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;GSK3B GO:0007165| signal transduction LYN;IMPA1;IMPA2;MAP2K1;BCR;SRC GO:1900034| GSK3B;CAMK2G 3859:[DB06616 DB04345] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;BLVRB;CYP3A4 3860:[DB06616 DB04836] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A2;LYN;ABCB1;SRC;SLC6A4 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0055085| transmembrane transport SLC6A2;SLC6A4;ABCB1 GO:0009636| response to toxin LYN;SLC6A4 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0010628| positive regulation of gene expression SRC;MAP2K1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0007420| brain development SLC6A4;BCR 3861:[DB06616 DB13192] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways GO:0043066| negative regulation of apoptotic process PROC;HCK;SRC GO:0050900| leukocyte migration LYN;PROC;SRC GO:0050728| negative regulation of inflammatory response BCR;PROC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0030335| positive regulation of cell migration F10;LYN GO:0007596| blood coagulation PROC;F9;LYN;F10 3862:[DB06616 DB00211] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;ADRA1A GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007275| multicellular organismal development ADRA1D;CDK2;CAMK2G;ADRA1B GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA1D;HCK GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0035556| intracellular signal transduction ADRA1B;BCR;ADRA1A;SRC;LYN;CAMK2G GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008283| cell proliferation SRC;ADRA1B;ADRA1D GO:0055085| transmembrane transport SLC15A1;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ADRA1A;ABL1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ABL1;ADRA1B GO:0006810| transport ABCB1;SLC15A1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction MAP2K1;ADRA1A;SRC;BCR;ADRA1B;ADRA1D;LYN GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 3863:[DB06616 DB01564] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01564|Calusterone AR common genes common pathways GO:0007165| signal transduction LYN;AR;MAP2K1;BCR;SRC GO:0006810| transport ABCB1;AR GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;AR GO:0042327| positive regulation of phosphorylation AR;LYN GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0051259| protein oligomerization AR;CAMK2G GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K2;SRC;MAP2K1;AR 3864:[DB06616 DB03058] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways GO:0002576| platelet degranulation LYN;CFD GO:0045087| innate immune response HCK;CFD;SRC;ABL1;LYN GO:0002376| immune system process HCK;CFD;SRC;LYN 3865:[DB06616 DB05005] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05005|CCX282 CCR9 common genes common pathways GO:0006935| chemotaxis CCR9;MAP2K1 GO:0007165| signal transduction LYN;SRC;BCR;CCR9;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCR9 3866:[DB06616 DB08008] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;LYN GO:0043065| positive regulation of apoptotic process SRC;DHODH;ABL1 GO:0042493| response to drug LYN;DHODH;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 3867:[DB06616 DB08063] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08063|1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE RXRA;NR1H3 common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;NR1H3;BCR;SRC GO:0007507| heart development RXRA;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RXRA;NR1H3 GO:0016032| viral reproduction HCK;SRC;LYN;RXRA GO:0050728| negative regulation of inflammatory response BCR;NR1H3 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;NR1H3;MAP2K1;MAP3K2;RXRA;CDK2 GO:0006355| regulation of transcription, DNA-dependent NR1H3;ABL1;RXRA 3868:[DB06616 DB01754] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01754|3,4-Dihydroxy-1-Methylquinolin-2(1h)-One PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;HCK;SRC GO:0007275| multicellular organismal development PIM1;CDK2;CAMK2G GO:0007346| regulation of mitotic cell cycle MAP3K2;PIM1;MAP2K1;MAP2K2 GO:0016310| phosphorylation PIM1;MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;PIM1;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0046777| protein autophosphorylation ABL1;HCK;SRC;BCR;LYN;CAMK2G;PIM1 GO:0007049| cell cycle SRC;PIM1;CDK2 GO:0008283| cell proliferation PIM1;SRC GO:0006915| apoptotic process ABL1;PIM1 3869:[DB06616 DB03686] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways GO:0031667| response to nutrient levels SRC;GSTP1 GO:0014003| oligodendrocyte development GSTP1;LYN GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0006805| xenobiotic metabolic process CYP2C8;GSTP1;CYP3A4 GO:0043066| negative regulation of apoptotic process GSTP1;HCK;SRC GO:0071222| cellular response to lipopolysaccharide GSTP1;SRC;BCR;ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;ABL1;LYN GO:0043200| response to amino acid stimulus LYN;GSTP1 GO:0009636| response to toxin GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1;GSTP1 GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0032869| cellular response to insulin stimulus GSTP1;SRC GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN 3870:[DB06616 DB03309] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways GO:0007275| multicellular organismal development EN2;CAMK2G;CDK2 GO:0006629| lipid metabolic process CYP3A4;SULT2B1 GO:0006355| regulation of transcription, DNA-dependent ABL1;EN2 GO:0008202| steroid metabolic process CYP2C8;SULT2B1;CYP3A4 GO:0030182| neuron differentiation MAP2K1;ABL1;EN2 GO:0008285| negative regulation of cell proliferation SULT2B1;LYN;MAP2K1 3871:[DB06616 DB08118] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08118|2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;GCK GO:0016310| phosphorylation CAMK2G;CDK2;LYN;GCK;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK 3872:[DB06616 DB04003] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways GO:0050690| regulation of defense response to virus by virus LCK;HCK GO:0006470| protein dephosphorylation CAMK2G;LCK GO:0016477| cell migration LCK;SRC GO:0050853| B cell receptor signaling pathway LYN;LCK;ABL1 GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;MAP2K1;LCK;SRC;MAP2K2;BCR;ABL1 GO:0031295| T cell costimulation SRC;LCK;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;LCK GO:0006468| protein phosphorylation ABL1;HCK;LCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2 GO:0030168| platelet activation SRC;LCK;LYN GO:0030097| hemopoiesis LYN;LCK GO:0038083| LYN;LCK;HCK;SRC;ABL1 GO:0042493| response to drug LCK;ABCB1;SRC;LYN GO:0050900| leukocyte migration SRC;LCK;LYN GO:0016032| viral reproduction SRC;LCK;HCK;LYN GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC GO:0042127| regulation of cell proliferation ABL1;LCK;SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;LCK;ABL1 GO:0045087| innate immune response SRC;LCK;HCK;ABL1;LYN 3873:[DB06616 DB04767] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways GO:0031667| response to nutrient levels F7;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F7 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC GO:0014070| response to organic cyclic compound F7;LYN GO:0007596| blood coagulation F7;LYN GO:0030335| positive regulation of cell migration LYN;F7 GO:0009725| response to hormone stimulus F7;LYN 3874:[DB06616 DB07195] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07195|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007165| signal transduction ESR1;LYN;BCR;SRC;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;ABL1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;MAP3K2;ESR1;CDK2 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 3875:[DB06616 DB08430] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08430|PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE LCTL common genes common pathways 3876:[DB06616 DB11127] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0034599| cellular response to oxidative stress ABL1;GPX1;TXNRD1 GO:0006629| lipid metabolic process GPX1;CYP3A4 GO:0042542| response to hydrogen peroxide SRC;GPX1 GO:0043066| negative regulation of apoptotic process HCK;GPX1;SRC GO:0055114| oxidation-reduction process CYP3A4;GPX1;TXNRD1;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0007165| signal transduction LYN;MAP2K1;TXNRD1;BCR;SRC GO:0006979| response to oxidative stress ABL1;GPX1 GO:0006915| apoptotic process GPX1;ABL1 GO:0008283| cell proliferation TXNRD1;SRC;GPX1 GO:0009636| response to toxin LYN;GPX1 3877:[DB06616 DB03429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03429|Cardiolipin SLC25A4 common genes common pathways GO:0016032| viral reproduction SLC25A4;LYN;SRC;HCK GO:0006810| transport SLC25A4;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC25A4 3878:[DB06616 DB04417] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04417|P-Nitrophenol SULT1A1;AMY2B common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;SULT1A1 GO:0006805| xenobiotic metabolic process CYP3A4;SULT1A1;CYP2C8 GO:0006629| lipid metabolic process SULT1A1;CYP3A4 3879:[DB06616 DB09204] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0008283| cell proliferation SRC;ADRA1B;ADRA1D GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ADRA1A;ABL1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0045453| bone resorption ADRB2;SRC GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction ADRA1D;LYN;ADRB2;MAP2K1;ADRB1;SRC;ADRA1A;BCR;ADRA1B GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ABL1;ADRA1B;ADRA1A GO:0006954| inflammatory response ORM1;LYN;HCK GO:0042493| response to drug LYN;ABCB1;SRC;ADRA1A GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0008284| positive regulation of cell proliferation CDK2;LYN;ADRA1D;HCK GO:0002576| platelet degranulation ORM1;LYN;ALB GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0035556| intracellular signal transduction ADRA1B;SRC;ADRA1A;BCR;CAMK2G;LYN GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CDK2;CAMK2G 3880:[DB06616 DB08388] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08388|5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE MMP13 common genes common pathways 3881:[DB06616 DB08826] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08826|Deferiprone UGT1A6 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4;UGT1A6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;UGT1A6 3882:[DB06616 DB08588] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0007155| cell adhesion DPP4;ABL1;HCK;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation SRC;DPP4;LYN 3883:[DB06616 DB01205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;GABRB3;GABRQ;GABRB1;GABRA5;GABRE;LYN;GABRP;GABRD;GABRA6 GO:0007420| brain development BCR;GABRA5 GO:0006810| transport ABCB1;GABRB3;GABRA3;GABRA5;GABRB1;GABRG2;GABRD;GABRB2;GABRA4;GABRA6;GABRA1 GO:0007417| central nervous system development LYN;GABRA4;SRC GO:0009791| post-embryonic development GABRG2;ABL1 GO:0009636| response to toxin GABRB1;LYN GO:0042493| response to drug SRC;ABCB1;GABRG3;LYN 3884:[DB06616 DB09185] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0006810| transport ABCB1;SLC6A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;SRC;LYN;SLC6A2;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 3885:[DB06616 DB08504] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways GO:0031295| T cell costimulation LYN;DPP4;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0008284| positive regulation of cell proliferation CDK2;LYN;DPP4;HCK GO:0007155| cell adhesion DPP4;ABL1;SRC;HCK 3886:[DB06616 DB03696] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03696|Lanosterol LSS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;LSS 3887:[DB06616 DB06013] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06013|Aldoxorubicin TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;ABL1;SRC 3888:[DB06616 DB05968] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05968|PR-104 TNF common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0045892| negative regulation of transcription, DNA-dependent TNF;SRC GO:0010033| response to organic substance TNF;CDK2 GO:0010628| positive regulation of gene expression TNF;MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;SRC;MAP2K2;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TNF;MAP3K2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNF GO:0051222| positive regulation of protein transport TNF;SRC GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0071803| positive regulation of podosome assembly SRC;TNF GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0006954| inflammatory response HCK;LYN;TNF GO:0050900| leukocyte migration SRC;LYN;TNF GO:0001934| positive regulation of protein phosphorylation ABL1;TNF;LYN GO:0010629| negative regulation of gene expression TNF;MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;TNF;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TNF GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;TNF GO:0009615| response to virus TNF;SRC GO:0050727| regulation of inflammatory response LYN;TNF;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0001932| regulation of protein phosphorylation TNF;LYN;MAP2K1 GO:0042127| regulation of cell proliferation TNF;ABL1;SRC 3889:[DB06616 DB01919] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01919|Pentanal PRKACA common genes common pathways GO:0034605| cellular response to heat LYN;PRKACA GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;LYN;CDK2;PRKACA;CAMK2G GO:0006468| protein phosphorylation MAP3K2;PRKACA;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0007596| blood coagulation LYN;PRKACA GO:0000086| G2/M transition of mitotic cell cycle CDK2;PRKACA;ABCB1 GO:0043393| regulation of protein binding SRC;PRKACA GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;PRKACA;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;PRKACA;CAMK2G GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2 3890:[DB06616 DB14004] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0016477| cell migration SRC;IL12B GO:0008283| cell proliferation SRC;IL12B GO:0045785| positive regulation of cell adhesion IL12B;SRC GO:0010033| response to organic substance CDK2;IL12B GO:0002376| immune system process LYN;SRC;HCK;IL23A GO:0007050| cell cycle arrest MAP2K1;IL12B;ABL1 GO:0097267| CYP2C8;CYP4A11 GO:0055114| oxidation-reduction process CYP2C8;CYP4A11;CYP3A4 GO:0006954| inflammatory response HCK;IL23A;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL23A;IL12B GO:0019373| epoxygenase P450 pathway CYP2C8;CYP4A11 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;IL12B;SRC GO:0045087| innate immune response LYN;SRC;HCK;IL23A;ABL1 3891:[DB06616 DB09148] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:1901216| ABL1;APP GO:0010629| negative regulation of gene expression APP;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;CYP4F2;CYP2J2;CYP3A4 GO:0001934| positive regulation of protein phosphorylation APP;LYN;ABL1 GO:0050885| neuromuscular process controlling balance ABL1;BCR;APP GO:0051897| positive regulation of protein kinase B signaling cascade APP;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;LYN;SRC;ABL1 GO:0045931| positive regulation of mitotic cell cycle APP;ABL1 GO:0043393| regulation of protein binding APP;SRC GO:0006805| xenobiotic metabolic process CYP2C8;CYP2J2;CYP3A4 GO:0006897| endocytosis ABL1;APP GO:0019373| epoxygenase P450 pathway CYP2J2;CYP4F2;CYP2C8 GO:0042327| positive regulation of phosphorylation LYN;APP GO:0002576| platelet degranulation LYN;APP GO:0043065| positive regulation of apoptotic process ABL1;SRC;APP GO:0007155| cell adhesion ABL1;SRC;HCK;APP GO:0045087| innate immune response ABL1;SRC;HCK;LYN;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0007399| nervous system development APP;CAMK2G GO:0031175| neuron projection development APP;LYN GO:0007596| blood coagulation CYP4F2;LYN GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;APP;MAP3K2 GO:0006915| apoptotic process ABL1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;APP GO:0010628| positive regulation of gene expression APP;MAP2K1;SRC GO:1900272| ABL1;APP GO:0008285| negative regulation of cell proliferation LYN;APP;MAP2K1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;APP;MAP3K2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP GO:0006979| response to oxidative stress ABL1;APP GO:0030900| forebrain development SRC;APP GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP4F2 GO:0097267| CYP4F2;CYP2C8 3892:[DB06616 DB02401] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02401|4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid LDHB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;LDHB 3893:[DB06616 DB03167] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03167|Pentabromophenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 3894:[DB06616 DB05786] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05786|Irofulven FUBP1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent FUBP1;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;FUBP1;SRC 3895:[DB06616 DB02279] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02279|Benzoylformic Acid HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;ABL1 GO:0055114| oxidation-reduction process HAO1;CYP3A4;CYP2C8 3896:[DB06616 DB08338] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08338|19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:1901796| CDK2;CSNK2A1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CSNK2A1 GO:0007049| cell cycle SRC;CSNK2A1;CDK2 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CSNK2A1;MAP2K1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;CSNK2A1 GO:0006468| protein phosphorylation MAP3K2;CSNK2A1;CAMK2G;LYN;CDK2;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;CDK2;CAMK2G;MAP3K2;CSNK2A1 3897:[DB06616 DB04172] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04172|[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine PLAU common genes common pathways GO:0042127| regulation of cell proliferation PLAU;ABL1;SRC GO:0006935| chemotaxis PLAU;MAP2K1 GO:0030335| positive regulation of cell migration LYN;PLAU GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;PLAU GO:0007596| blood coagulation PLAU;LYN GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU 3898:[DB06616 DB06907] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR 3899:[DB06616 DB04217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04217|L-2-amino-3-butynoic acid CTH;sufS common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;ABL1 3900:[DB06616 DB05014] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;RET;KDR;MAP2K1;HCK;ABL1;FGFR3;MAP3K2;FGFR1;CAMK2G;PDGFRB;CDK2;LYN;FLT3 GO:0030154| cell differentiation FLT3;CAMK2G;HCK;KDR GO:0035791| platelet-derived growth factor receptor-beta signaling pathway PDGFRB;ABL1 GO:0036120| SRC;PDGFRB GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation CAMK2G;FGFR1;PDGFRB;LYN;CDK2;FLT3;FGFR3;MAP3K2;ABL1;MAP2K2;BCR;SRC;RET;MAP2K1;KDR;HCK GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;FGFR3;PDGFRB;LYN;FLT3 GO:0030335| positive regulation of cell migration PDGFRB;LYN;RET;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT3;LYN;PDGFRB;HCK;KDR;RET GO:0007165| signal transduction MAP2K1;BCR;RET;SRC;LYN;PDGFRB GO:0007420| brain development BCR;FGFR1 GO:0030097| hemopoiesis FLT3;LYN GO:0065009| regulation of molecular function CAMK2G;RET GO:0032956| regulation of actin cytoskeleton organization ABL1;PDGFRB GO:0070374| positive regulation of ERK1 and ERK2 cascade FGFR3;PDGFRB;KDR;MAP2K1;SRC;MAP2K2;ABL1 GO:0006915| apoptotic process ABL1;FGFR3 GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0030182| neuron differentiation RET;MAP2K1;ABL1 GO:0016477| cell migration SRC;PDGFRB;FGFR1 GO:0009636| response to toxin PDGFRB;LYN GO:0014070| response to organic cyclic compound PDGFRB;LYN GO:0043406| positive regulation of MAP kinase activity FLT3;PDGFRB;FGFR1;SRC GO:0007411| axon guidance RET;SRC GO:0014911| positive regulation of smooth muscle cell migration PDGFRB;SRC GO:0097028| dendritic cell differentiation FLT3;LYN GO:0046777| protein autophosphorylation ABL1;HCK;KDR;SRC;BCR;FLT3;LYN;PDGFRB;FGFR1;CAMK2G;FGFR3 GO:0010628| positive regulation of gene expression MAP2K1;RET;SRC GO:2000573| positive regulation of DNA biosynthetic process PDGFRB;SRC GO:0007275| multicellular organismal development CDK2;PDGFRB;CAMK2G;KDR GO:0018108| peptidyl-tyrosine phosphorylation PDGFRB;FGFR1;FLT3;LYN;FGFR3;ABL1;SRC;RET;MAP2K2;BCR;HCK;MAP2K1;KDR GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein FGFR3;FLT3;LYN GO:0042127| regulation of cell proliferation FGFR1;SRC;ABL1 GO:0042472| inner ear morphogenesis FGFR1;BCR GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1;PDGFRB GO:0007155| cell adhesion ABL1;HCK;RET;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;CDK2 GO:0008360| regulation of cell shape HCK;KDR GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;FLT3;MAP3K2 GO:0007399| nervous system development RET;CAMK2G GO:0043065| positive regulation of apoptotic process PDGFRB;ABL1;SRC GO:0042542| response to hydrogen peroxide SRC;PDGFRB GO:0008284| positive regulation of cell proliferation FGFR3;PDGFRB;FGFR1;FLT3;CDK2;LYN;HCK;KDR GO:0006935| chemotaxis PDGFRB;MAP2K1 GO:0071300| cellular response to retinoic acid RET;LYN GO:0035556| intracellular signal transduction CAMK2G;PDGFRB;LYN;BCR;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0030155| regulation of cell adhesion ABL1;RET GO:0043066| negative regulation of apoptotic process HCK;KDR;SRC;PDGFRB GO:0001934| positive regulation of protein phosphorylation KDR;ABL1;LYN GO:0038083| LYN;KDR;HCK;SRC;ABL1 GO:0010629| negative regulation of gene expression FGFR1;MAP2K2;KDR;MAP2K1 GO:0042493| response to drug LYN;ABCB1;RET;SRC GO:0006355| regulation of transcription, DNA-dependent FGFR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;RET;SRC;MAP2K2;MAP3K2;CDK2 GO:0019221| cytokine-mediated signaling pathway HCK;FLT3 GO:0000165| MAPKKK cascade MAP2K1;RET;MAP2K2;PDGFRB;FGFR1;CAMK2G;FGFR3 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;FGFR3;FGFR1;PDGFRB GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0010976| positive regulation of neuron projection development RET;LYN;FGFR1 GO:0016032| viral reproduction LYN;KDR;HCK;SRC 3901:[DB06616 DB11590] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes common pathways GO:0034599| cellular response to oxidative stress ABL1;GSR;GPX1;SOD2 GO:0048678| response to axon injury MTR;LYN GO:0042127| regulation of cell proliferation FXYD2;SRC;ABL1 GO:0007399| nervous system development MTR;CAMK2G GO:0006629| lipid metabolic process GPX1;CYP3A4 GO:0071732| cellular response to nitric oxide CDK2;MTR GO:0042542| response to hydrogen peroxide SRC;GPX1 GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process ALB;HCK;GPX1;SRC GO:0050900| leukocyte migration LYN;SLC7A11;SRC GO:0055114| oxidation-reduction process GSR;CYP2C8;GPX1;SOD2;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC GO:0010506| regulation of autophagy ITPR1;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0006816| calcium ion transport ITPR1;CAMK2G GO:0030168| platelet activation ITPR1;SRC;LYN GO:0006810| transport ABCB1;FXYD2 GO:0030335| positive regulation of cell migration SOD2;LYN GO:0007165| signal transduction MAP2K1;BCR;SRC;ITPR1;LYN GO:0007420| brain development BCR;SLC7A11 GO:0065009| regulation of molecular function CAMK2G;ITPR1 GO:0006979| response to oxidative stress SLC7A11;ABL1;GPX1 GO:0006813| potassium ion transport FXYD2;CDK2 GO:0055085| transmembrane transport ABCB1;ITPR1 GO:0006915| apoptotic process ABL1;ITPR1;GPX1 GO:0008283| cell proliferation GPX1;SRC GO:0009636| response to toxin GPX1;LYN;SLC7A11 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;SOD2 GO:0009791| post-embryonic development ITPR1;ABL1 3902:[DB06616 DB08607] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08607|(5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE CYP2C8;FABP4 common genes CYP2C8 common pathways GO:0002933| CYP2C8;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent FABP4;SRC GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0097267| CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006082| organic acid metabolic process CYP2C8 GO:0050727| regulation of inflammatory response LYN;FABP4;HCK GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8 3903:[DB06616 DB02153] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02153|3-Sulfinoalanine PAPOLA;aroH;GSR;PRDX2;def;FABP4 common genes common pathways GO:0055114| oxidation-reduction process GSR;CYP2C8;PRDX2;CYP3A4 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;PRDX2;MAP3K2 GO:0050727| regulation of inflammatory response HCK;FABP4;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;PRDX2 GO:0034599| cellular response to oxidative stress PRDX2;GSR;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;FABP4 GO:0006979| response to oxidative stress PRDX2;ABL1 3904:[DB06616 DB06481] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06481|Manitimus DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;LYN GO:0042493| response to drug DHODH;ABCB1;SRC;LYN GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0043065| positive regulation of apoptotic process SRC;DHODH;ABL1 3905:[DB06616 DB07015] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;DPP4;LYN GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;DPP4 GO:0007155| cell adhesion SRC;HCK;ABL1;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 3906:[DB06616 DB00167] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0008283| cell proliferation SRC;BCAT1 GO:0055085| transmembrane transport ABCB1;SLC16A10 GO:0000082| G1/S transition of mitotic cell cycle BCAT1;CDK2;CAMK2G GO:0055114| oxidation-reduction process ACADSB;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;ACADSB 3907:[DB06616 DB02459] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways GO:0002376| immune system process LYN;SRC;HCK;CFB GO:0045087| innate immune response LYN;ABL1;CFB;SRC;HCK 3908:[DB06616 DB03845] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03845|P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate DTYMK common genes common pathways GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;DTYMK;LYN;CDK2;CAMK2G;MAP3K2 GO:0007049| cell cycle DTYMK;CDK2;SRC GO:0008283| cell proliferation SRC;DTYMK 3909:[DB06616 DB02638] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AVPR1B;AVPR1A GO:0007165| signal transduction SRC;BCR;AVPR2;MAP2K1;AVPR1A;LYN;AVPR1B GO:0010033| response to organic substance CDK2;AVPR1A GO:0010628| positive regulation of gene expression SRC;AVPR2;MAP2K1 GO:0008284| positive regulation of cell proliferation AVPR1A;CDK2;LYN;AVPR2;HCK 3910:[DB06616 DB05159] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05159|CCX915 CCR2 common genes common pathways GO:0006954| inflammatory response LYN;HCK;CCR2 GO:0016032| viral reproduction LYN;CCR2;SRC;HCK GO:0019221| cytokine-mediated signaling pathway CCR2;HCK GO:0006935| chemotaxis MAP2K1;CCR2 GO:0007165| signal transduction LYN;BCR;CCR2;SRC;MAP2K1 GO:0030097| hemopoiesis LYN;CCR2 GO:0007204| elevation of cytosolic calcium ion concentration CCR2;ABL1 3911:[DB06616 DB06069] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06069|XMT-1001 TOP1 common genes common pathways GO:0016310| phosphorylation MAP3K2;TOP1;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0042493| response to drug LYN;TOP1;ABCB1;SRC GO:0006260| DNA replication TOP1;CDK2 GO:0016032| viral reproduction SRC;HCK;TOP1;LYN GO:0018105| peptidyl-serine phosphorylation TOP1;CAMK2G;CDK2;SRC 3912:[DB06616 DB02074] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02074|Butenoic Acid FABP1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide ABL1;FABP1 GO:0071456| cellular response to hypoxia FABP1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;FABP1 GO:0043066| negative regulation of apoptotic process FABP1;SRC;HCK 3913:[DB06616 DB14033] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 3914:[DB06616 DB05712] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05712|AZD-9684 CPB2 common genes common pathways GO:0042493| response to drug LYN;SRC;ABCB1;CPB2 GO:0007596| blood coagulation LYN;CPB2 3915:[DB06616 DB00467] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug LYN;CYP1A2;ABCB1;SRC GO:0006974| response to DNA damage stimulus TOP2A;CDK2;LYN;ABL1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;TOP2A GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 3916:[DB06616 DB07013] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07013|TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE MMP13 common genes common pathways 3917:[DB06616 DB08837] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration CHRNA9;ABL1 GO:0006813| potassium ion transport CDK2;KCNA1 GO:0007420| brain development KCNA1;BCR GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CHRNA9 GO:0009636| response to toxin LYN;SLC22A8 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;SLC22A5;SLC47A1;ABCB1;SLC22A2 GO:0055085| transmembrane transport SLC22A5;SLC22A8;SLC22A3;SLC22A4;SLC22A1;SLC22A2;ABCB1;SLC47A1;KCNA1 GO:0042472| inner ear morphogenesis CHRNA9;BCR GO:0006816| calcium ion transport CAMK2G;CHRNA9 3918:[DB06616 DB00187] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00187|Esmolol ADRB1;CYP2D6 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction LYN;SRC;ADRB1;BCR;MAP2K1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 3919:[DB06616 DB03336] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03336|BIA COMT common genes common pathways GO:0032496| response to lipopolysaccharide COMT;BCR GO:0042493| response to drug SRC;ABCB1;LYN;COMT GO:0014070| response to organic cyclic compound COMT;LYN 3920:[DB06616 DB12693] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;HTR2A GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;HTR2A GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;HTR2A;LYN;CDK2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;LYN;SRC;ABL1 GO:0042493| response to drug ABCB1;SRC;HTR2A;LYN GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 3921:[DB06616 DB06817] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06817|Raltegravir pol;UGT1A1 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;BCR GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug LYN;UGT1A1;ABCB1;SRC GO:0017144| drug metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0010033| response to organic substance UGT1A1;CDK2 GO:0014070| response to organic cyclic compound UGT1A1;LYN 3922:[DB06616 DB04715] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04715|IMIDAZOPYRIDAZIN 1 PIM1 common genes common pathways GO:0046777| protein autophosphorylation CAMK2G;LYN;PIM1;ABL1;BCR;SRC;HCK GO:0007049| cell cycle SRC;PIM1;CDK2 GO:0008283| cell proliferation SRC;PIM1 GO:0006915| apoptotic process ABL1;PIM1 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;PIM1 GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;PIM1;CDK2;LYN;CAMK2G GO:0007346| regulation of mitotic cell cycle PIM1;MAP3K2;MAP2K2;MAP2K1 GO:0043066| negative regulation of apoptotic process HCK;SRC;PIM1 GO:0007275| multicellular organismal development CAMK2G;CDK2;PIM1 3923:[DB06616 DB06892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes MAP2K1 common pathways GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0048538| thymus development MAP2K1;ABL1 GO:0030878| thyroid gland development MAP2K1 GO:1903800| MAP2K1;MAP2K2 GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0090170| regulation of Golgi inheritance MAP2K1;MAP2K2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0006928| cellular component movement MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;MAP2K2 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2 GO:0030182| neuron differentiation ABL1;MAP2K1 GO:0030216| keratinocyte differentiation MAP2K1 GO:0060711| labyrinthine layer development MAP2K1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2 GO:0007507| heart development MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1 GO:0050772| positive regulation of axonogenesis MAP2K1 GO:0006935| chemotaxis MAP2K1 GO:0021697| cerebellar cortex formation MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;LYN GO:0048679| regulation of axon regeneration MAP2K1 GO:0060674| placenta blood vessel development MAP2K1 GO:0001932| regulation of protein phosphorylation LYN;MAP2K1 GO:0048870| cell motility MAP2K1 GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G GO:0060324| face development MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1 GO:0090398| cellular senescence MAP2K1 GO:0060425| lung morphogenesis MAP2K1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1 GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;MAP3K2 GO:0035897| proteolysis in other organism MAP2K1;MAP2K2 GO:0060440| trachea formation MAP2K1 3924:[DB06616 DB05553] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05553|Regrelor P2RY12 common genes common pathways GO:0007596| blood coagulation P2RY12;LYN GO:0030168| platelet activation LYN;P2RY12;SRC GO:0065009| regulation of molecular function P2RY12;CAMK2G GO:0007165| signal transduction MAP2K1;SRC;BCR;P2RY12;LYN GO:0051924| regulation of calcium ion transport CAMK2G;P2RY12 3925:[DB06616 DB14031] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14031|Tretamine BCHE common genes common pathways GO:0042493| response to drug LYN;BCHE;ABCB1;SRC GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 3926:[DB06616 DB05045] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05045|Obinepitide NPY4R;NPY2R common genes common pathways GO:0007165| signal transduction LYN;SRC;NPY2R;BCR;NPY4R;MAP2K1 GO:0065009| regulation of molecular function CAMK2G;NPY2R GO:0007204| elevation of cytosolic calcium ion concentration ABL1;NPY2R 3927:[DB06616 DB08672] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways GO:0043542| endothelial cell migration DPP4;ABL1 GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0008284| positive regulation of cell proliferation HCK;DPP4;CDK2;LYN GO:0031295| T cell costimulation SRC;LYN;DPP4 3928:[DB06616 DB01863] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01863|Inositol 1,3,4,5-Tetrakisphosphate AKT1;PLEKHA4;BTK;DAPP1;ITPKA;CYTH2;CYTH3;PDPK1 common genes common pathways GO:0007165| signal transduction AKT1;LYN;MAP2K1;SRC;BCR;ITPKA;DAPP1 GO:0009725| response to hormone stimulus AKT1;LYN GO:0010907| positive regulation of glucose metabolic process AKT1;SRC GO:1900182| SRC;AKT1 GO:0065009| regulation of molecular function CYTH2;CAMK2G;CYTH3 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol PDPK1;ABL1 GO:0002376| immune system process SRC;BTK;HCK;LYN GO:0006979| response to oxidative stress AKT1;ABL1 GO:0030889| negative regulation of B cell proliferation LYN;BTK GO:0030154| cell differentiation HCK;AKT1;CAMK2G GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;PDPK1;AKT1;MAP3K2;ABL1;ITPKA;MAP2K2;BCR;SRC;MAP2K1;BTK;HCK GO:0032869| cellular response to insulin stimulus SRC;PDPK1;AKT1 GO:0071456| cellular response to hypoxia SRC;AKT1 GO:0030168| platelet activation SRC;AKT1;PDPK1;LYN GO:0031295| T cell costimulation AKT1;LYN;PDPK1;SRC GO:0016310| phosphorylation CDK2;LYN;PDPK1;CAMK2G;AKT1;MAP3K2;ABL1;MAP2K1;BTK;HCK;ITPKA;MAP2K2;BCR;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;BTK;HCK GO:0010033| response to organic substance BTK;CDK2;AKT1 GO:0006464| protein modification process ABL1;AKT1 GO:0050853| B cell receptor signaling pathway ABL1;BTK;LYN GO:0046777| protein autophosphorylation SRC;BCR;HCK;BTK;ABL1;AKT1;CAMK2G;PDPK1;LYN GO:0034614| cellular response to reactive oxygen species SRC;BTK;AKT1 GO:0045785| positive regulation of cell adhesion SRC;CYTH3 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;AKT1;PDPK1;CAMK2G GO:0006915| apoptotic process BTK;ABL1;AKT1 GO:0038095| BTK;PDPK1;LYN GO:0008283| cell proliferation AKT1;SRC GO:0016477| cell migration SRC;PDPK1 GO:0006470| protein dephosphorylation CAMK2G;DAPP1 GO:0032148| activation of protein kinase B activity SRC;PDPK1;AKT1 GO:0045087| innate immune response BTK;HCK;SRC;ABL1;LYN GO:0007399| nervous system development AKT1;CAMK2G GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;AKT1 GO:0071260| cellular response to mechanical stimulus AKT1;MAP3K2 GO:0006974| response to DNA damage stimulus ABL1;AKT1;CDK2;LYN GO:1901796| CDK2;AKT1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;AKT1 GO:0043304| regulation of mast cell degranulation LYN;PDPK1 GO:0008284| positive regulation of cell proliferation AKT1;CDK2;LYN;HCK GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;PDPK1;AKT1;SRC GO:0035556| intracellular signal transduction LYN;PDPK1;CAMK2G;AKT1;BTK;BCR;SRC GO:0002902| regulation of B cell apoptosis LYN;BTK GO:0006897| endocytosis CYTH2;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKT1 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;AKT1;HCK GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PDPK1;SRC GO:0007275| multicellular organismal development CDK2;CAMK2G;AKT1 GO:0007498| mesoderm development BTK;HCK GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;BCR;MAP2K2;HCK;BTK;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;BTK;SRC GO:0030036| actin cytoskeleton organization PDPK1;ITPKA;BCR;ABL1;CYTH2 GO:0002250| adaptive immune response LYN;BTK GO:0002553| histamine secretion by mast cell BTK;LYN GO:0006954| inflammatory response AKT1;LYN;HCK GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process AKT1;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;AKT1;LYN GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;AKT1 GO:0038083| ABL1;SRC;HCK;BTK;LYN GO:0006355| regulation of transcription, DNA-dependent BTK;ABL1;PDPK1 GO:0007173| epidermal growth factor receptor signaling pathway AKT1;PDPK1;SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;AKT1;MAP3K2;CDK2 3929:[DB06616 DB07176] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 3930:[DB06616 DB08515] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08515|(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA6;PSMA7;PSMB1;PSMB2;PSMB3;PSMB4;PSMB5;PSMB6;PSMB7 common genes common pathways GO:0016032| viral reproduction PSMB6;SRC;PSMA3;HCK;PSMB4;PSMA4;LYN;PSMB2;PSMA7;PSMB7;PSMB5;PSMB1;PSMB3 GO:0000165| MAPKKK cascade PSMA5;PSMB1;PSMB3;PSMA6;PSMB7;PSMB5;PSMA1;PSMA7;PSMB2;PSMA4;CAMK2G;PSMB4;PSMA3;MAP2K1;MAP2K2;PSMB6;PSMA2 GO:1902036| PSMA3;PSMB6;PSMA2;ABL1;PSMB1;PSMB3;PSMA6;PSMA5;PSMB7;PSMB5;PSMA7;PSMA1;PSMB2;PSMA4;PSMB4 GO:0009615| response to virus PSMA2;SRC GO:0050727| regulation of inflammatory response HCK;PSMA6;LYN GO:0051436| negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle PSMA2;PSMB6;PSMA3;PSMA4;PSMB4;PSMA7;PSMA1;CDK2;PSMB2;PSMB5;PSMB7;PSMB3;PSMA6;PSMB1;PSMA5 GO:0002223| stimulatory C-type lectin receptor signaling pathway PSMB5;PSMB7;PSMA5;PSMA6;PSMB3;PSMB1;PSMB4;PSMA4;PSMB2;LYN;PSMA1;PSMA7;PSMB6;SRC;PSMA3;PSMA2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;PSMB6;PSMA3;PSMA2;PSMB7;PSMB5;PSMB1;PSMA6;PSMB3;PSMA5;PSMA4;PSMB4;PSMA7;PSMA1;PSMB2 GO:0014070| response to organic cyclic compound PSMB2;LYN GO:0038095| PSMA2;PSMB6;PSMA3;PSMB4;PSMA4;PSMB2;LYN;PSMA1;PSMA7;PSMB7;PSMB5;PSMA5;PSMB1;PSMB3;PSMA6 GO:0055085| transmembrane transport PSMA3;ABCB1;PSMB6;PSMA2;PSMB1;PSMB3;PSMA6;PSMA5;PSMB7;PSMB5;PSMA7;PSMA1;PSMB2;PSMA4;PSMB4 GO:0006979| response to oxidative stress ABL1;PSMB5 GO:0002376| immune system process HCK;SRC;LYN;PSMA1 3931:[DB06616 DB01403] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;ABL1;SRC GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0006954| inflammatory response HCK;HRH1;LYN GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;DRD3;HTR2A;LYN;ABCB1;ADRA1A;DRD2;SRC;HTR2C;DRD1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0032148| activation of protein kinase B activity ADRA2B;ADRA2C;ADRA2A;SRC GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1;CHRM2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0035556| intracellular signal transduction ADRA1B;BCR;ADRA1A;DRD2;SRC;CAMK2G;LYN GO:0009615| response to virus SRC;CHRM2 GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;DRD3;LYN;CDK2;HTR2A;CHRM1;ADRA1D GO:0007275| multicellular organismal development ADRA1B;CAMK2G;CDK2;ADRA1D GO:0048678| response to axon injury LYN;DRD2 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;MAP2K1;LYN GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC;HTR2A GO:0010628| positive regulation of gene expression DRD1;SRC;MAP2K1 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0000187| activation of MAPK activity ADRA2B;DRD4;MAP3K2;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K2;DRD2;SRC;ADRA1A;MAP2K1;HTR2C;ABL1 GO:0009636| response to toxin LYN;DRD2 GO:0008283| cell proliferation CHRM1;CHRM5;ADRA1D;CHRM3;ADRA1B;SRC;CHRM4 GO:0030900| forebrain development DRD2;SRC GO:1903351| ABL1;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0007165| signal transduction DRD1;ADRA2A;HTR2C;ADRA1B;DRD5;CHRM4;MAP2K1;SRC;DRD2;ADRA1A;BCR;DRD3;CHRM2;HTR2A;LYN;ADRA2B;ADRA2C;CHRM1;DRD4;HRH1;CHRM3;CHRM5;ADRA1D GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0030168| platelet activation ADRA2B;LYN;ADRA2C;ADRA2A;SRC GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A;HTR2A;ADRA1D GO:0030335| positive regulation of cell migration ADRA2A;DRD1;LYN GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8 3932:[DB06616 DB04648] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04648|S-propylamine-L-cysteine ARG1 common genes common pathways GO:0043434| response to peptide hormone stimulus LYN;ARG1 GO:0002376| immune system process LYN;ARG1;HCK;SRC GO:0043200| response to amino acid stimulus ARG1;LYN GO:0070301| cellular response to hydrogen peroxide ABL1;ARG1 GO:0032496| response to lipopolysaccharide BCR;ARG1 GO:0048678| response to axon injury LYN;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ARG1;ABL1 GO:0045087| innate immune response ABL1;ARG1;SRC;HCK;LYN GO:0042493| response to drug LYN;SRC;ABCB1;ARG1 GO:0002250| adaptive immune response LYN;ARG1 3933:[DB06616 DB03306] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03306|RU78300 SRC common genes SRC common pathways GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0045087| innate immune response LYN;ABL1;SRC;HCK GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC GO:0071398| cellular response to fatty acid SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN GO:0086098| SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071498| cellular response to fluid shear stress SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0038128| SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0038096| HCK;SRC;ABL1;LYN GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction SRC;HCK;LYN GO:0034332| adherens junction organization SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0050900| leukocyte migration LYN;SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;MAP3K2 GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0042493| response to drug LYN;SRC;ABCB1 GO:0038083| LYN;ABL1;HCK;SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0002376| immune system process SRC;HCK;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0098609| SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0036120| SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;BCR;SRC;ABL1 GO:0051895| negative regulation of focal adhesion assembly SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2 GO:0045785| positive regulation of cell adhesion SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC 3934:[DB06616 DB00137] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00137|Lutein ALB common genes common pathways GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB 3935:[DB06616 DB08954] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0000165| MAPKKK cascade CAMK2G;GRIN2B;GRIN1;MAP2K2;MAP2K1 GO:0006816| calcium ion transport GRIN1;CAMK2G GO:1901216| ABL1;GRIN2B GO:0043065| positive regulation of apoptotic process ABL1;SRC;GRIN1 GO:0048013| ephrin receptor signaling pathway SRC;GRIN2B;LYN;GRIN1 GO:0065009| regulation of molecular function GRIN1;CAMK2G;GRIN2B GO:0006810| transport ABCB1;GRIN2B 3936:[DB06616 DB01345] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01345|Potassium cation ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;SRC;ATP1A1;LYN GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 GO:0006813| potassium ion transport CDK2;ATP1A1 3937:[DB06616 DB11338] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;CXCL10;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;CXCL10 GO:0065009| regulation of molecular function CAMK2G;CSF2RA GO:0060333| interferon-gamma-mediated signaling pathway HCK;VCAM1;CAMK2G GO:0030168| platelet activation SRC;COL1A1;LYN GO:0098609| VCAM1;SRC GO:0030335| positive regulation of cell migration COL1A1;LYN;CXCL10 GO:0034605| cellular response to heat CXCL10;LYN GO:0043434| response to peptide hormone stimulus LYN;COL1A1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway COL1A1;SRC GO:0007596| blood coagulation LYN;COL1A1 GO:0007155| cell adhesion VCAM1;ABL1;HCK;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;COL1A1 GO:0071222| cellular response to lipopolysaccharide CXCL10;ABL1;BCR;SRC GO:0009615| response to virus CXCL10;SRC GO:0042542| response to hydrogen peroxide SRC;COL1A1 GO:0006935| chemotaxis MAP2K1;CXCL10 GO:0008284| positive regulation of cell proliferation HCK;CXCL10;LYN;CDK2 GO:0071300| cellular response to retinoic acid COL1A1;LYN GO:0009612| response to mechanical stimulus COL1A1;SRC GO:0071560| cellular response to transforming growth factor beta stimulus COL1A1;SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;MAP2K2;BCR;CSF2RA;HCK;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;CXCL10 GO:0032496| response to lipopolysaccharide CXCL10;VCAM1;BCR GO:0019221| cytokine-mediated signaling pathway HCK;CSF2RA GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;CSF2RA;MAP2K2 GO:0006954| inflammatory response CXCL10;LYN;HCK GO:0016032| viral reproduction LYN;VCAM1;HCK;SRC GO:0050900| leukocyte migration COL1A1;SRC;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;VCAM1 GO:0042493| response to drug ABCB1;SRC;COL1A1;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;COL1A1;SRC;CDK2;MAP3K2 GO:0031667| response to nutrient levels SRC;COL1A1 3938:[DB06616 DB00505] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0007399| nervous system development CHRM2;CAMK2G;CHRM1;CHRM3 GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0008283| cell proliferation CHRM3;CHRM1;SRC GO:0007165| signal transduction CHRM2;LYN;CHRM1;CHRM3;MAP2K1;SRC;BCR 3939:[DB06616 DB08490] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08490|CTS-1027 MMP13 common genes common pathways 3940:[DB06616 DB08775] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08775|Nα-[(Benzyloxy)carbonyl]-N-[(2S)-4-fluoro-3-oxo-2-butanyl]-L-tyrosinamide CTSF common genes common pathways 3941:[DB06616 DB09499] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09499|Thiosulfuric acid TST common genes common pathways 3942:[DB06616 DB00166] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0006979| response to oxidative stress LIAS;ABL1 GO:0001843| neural tube closure ABL1;LIAS GO:0006810| transport ABCB1;SLC5A6 GO:0071375| cellular response to peptide hormone stimulus SRC;POR GO:0006464| protein modification process LIPT1;ABL1 GO:0055085| transmembrane transport ABCB1;SLC5A6 GO:0006629| lipid metabolic process LIPT1;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;POR;HCK GO:0006805| xenobiotic metabolic process CYP2C8;POR;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;LIAS GO:0006954| inflammatory response LYN;LIAS;HCK GO:0055114| oxidation-reduction process CYP3A4;POR;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;POR GO:0042493| response to drug LYN;SRC;ABCB1;POR 3943:[DB06616 DB04149] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PDE4B;PDE4D GO:0050900| leukocyte migration PDE4B;SRC;LYN;PDE4D GO:0007165| signal transduction PDE4D;LYN;SRC;BCR;MAP2K1;PDE4B 3944:[DB06616 DB08370] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways GO:0032869| cellular response to insulin stimulus GSTP1;SRC GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1;GSTP1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1 GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0009636| response to toxin LYN;GSTP1 GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:0034599| cellular response to oxidative stress GSTP1;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;GSTP1;ABL1 GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK GO:0014003| oligodendrocyte development GSTP1;LYN GO:0031667| response to nutrient levels GSTP1;SRC 3945:[DB06616 DB00837] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0007165| signal transduction LYN;GABBR1;SRC;BCR;MAP2K1 GO:0006810| transport ABCB1;GABRA1 3946:[DB06616 DB06785] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06785|Ganirelix GNRHR common genes common pathways GO:0007275| multicellular organismal development GNRHR;CAMK2G;CDK2 GO:0007165| signal transduction MAP2K1;BCR;SRC;GNRHR;LYN 3947:[DB06616 DB11235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007399| nervous system development CAMK2G;CHRM1;CHRM2;CHRM3 GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0007165| signal transduction CHRM5;HRH1;CHRM3;CHRM1;CHRM2;LYN;SRC;BCR;CHRM4;MAP2K1 GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0008283| cell proliferation CHRM5;CHRM3;CHRM1;SRC;CHRM4 3948:[DB06616 DB13620] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0042493| response to drug LYN;ATP1A1;SRC;ABCB1 GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0007155| cell adhesion ABL1;SRC;HCK;ATP4B GO:0032496| response to lipopolysaccharide BCR;ATP4B GO:0042127| regulation of cell proliferation ABL1;SRC;FXYD2 GO:0055085| transmembrane transport ABCB1;SLC12A1 GO:0006813| potassium ion transport SLC12A1;ATP4A;FXYD2;ATP1A1;CDK2;ATP4B GO:0006810| transport SLC12A1;ABCB1;ATP4A;FXYD2 3949:[DB06616 DB01191] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01191|Dexfenfluramine SLC6A4;HTR2C;CYP2D6;CYP1A2;CYP2E1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009636| response to toxin LYN;SLC6A4 GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2C;ABL1;MAP2K2;SRC;MAP2K1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance CDK2;CYP1A2;SLC6A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0007420| brain development BCR;SLC6A4 GO:0007165| signal transduction MAP2K1;BCR;SRC;HTR2C;LYN GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug LYN;CYP2E1;CYP1A2;HTR2C;SLC6A4;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6 3950:[DB06616 DB05137] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways GO:0006816| calcium ion transport CHRNA7;CHRNA10;CAMK2G;CHRNA9 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;CHRNA7 GO:0042472| inner ear morphogenesis CHRNA9;CHRNA10;BCR GO:0042127| regulation of cell proliferation CHRNA10;SRC;ABL1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;CHRNA7 GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRNA10;CHRNA7;CHRNA9;LYN GO:0007204| elevation of cytosolic calcium ion concentration CHRNA9;ABL1;CHRNA10 3951:[DB06616 DB03496] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03496|Alvocidib CDK2;CDK5;CDK9;CDK1;CDK6;EGFR;CDK4;CDK8;CDK7;PYGM;PYGB;PYGL;UGT1A1;ABCG2 common genes CDK2 common pathways GO:0007275| multicellular organismal development EGFR;CAMK2G;CDK2;CDK4 GO:0048678| response to axon injury CDK1;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;EGFR;MAP2K1;SRC;MAP2K2;BCR;LYN GO:0007265| Ras protein signal transduction CDK2 GO:0051436| negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle CDK2;CDK1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042127| regulation of cell proliferation CDK4;CDK6;EGFR;SRC;ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1;CDK1 GO:0032496| response to lipopolysaccharide UGT1A1;BCR GO:0051298| centrosome duplication CDK2 GO:0006281| DNA repair CDK1;CDK7;CDK9;CDK2;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0006974| response to DNA damage stimulus CDK9;CDK7;LYN;CDK2;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2 GO:0007399| nervous system development CDK5;CAMK2G GO:0042981| regulation of apoptotic process MAP3K2;CDK5;MAP2K1;MAP2K2 GO:0031571| mitotic cell cycle G1/S transition DNA damage checkpoint CDK2 GO:2000145| regulation of cell motility CDK6;ABL1;EGFR GO:0035556| intracellular signal transduction BCR;SRC;EGFR;CAMK2G;LYN GO:0021697| cerebellar cortex formation MAP2K1;CDK5 GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process HCK;EGFR;SRC;CDK1 GO:1901796| CDK2;CDK5 GO:0032298| positive regulation of DNA-dependent DNA replication initiation CDK2 GO:0043065| positive regulation of apoptotic process CDK4;ABL1;SRC GO:0008284| positive regulation of cell proliferation CDK4;LYN;CDK2;EGFR;HCK GO:0071732| cellular response to nitric oxide CDK2 GO:0018105| peptidyl-serine phosphorylation CDK1;CAMK2G;CDK5;CDK2;SRC GO:0042542| response to hydrogen peroxide CDK1;SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR;CDK4 GO:0009615| response to virus SRC;CDK6 GO:0071222| cellular response to lipopolysaccharide CDK4;BCR;SRC;ABL1 GO:0000278| mitotic cell cycle CDK1;ABL1 GO:0001934| positive regulation of protein phosphorylation EGFR;ABL1;LYN GO:1901216| ABL1;CDK5 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;EGFR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;CDK7;MAP3K2;MAP2K1;EGFR;MAP2K2;SRC GO:0042493| response to drug SRC;ABCB1;ABCG2;UGT1A1;CDK4;CDK1;CDK9;LYN GO:0007346| regulation of mitotic cell cycle MAP3K2;CDK9;MAP2K1;MAP2K2;CDK8 GO:0038083| LYN;SRC;EGFR;HCK;ABL1 GO:0006355| regulation of transcription, DNA-dependent CDK9;CDK7;CDK8;ABL1 GO:0000165| MAPKKK cascade MAP2K2;EGFR;MAP2K1;CAMK2G GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK6;CDK2;CDK1 GO:0006260| DNA replication CDK1;CDK2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;EGFR GO:0000082| G1/S transition of mitotic cell cycle CDK4;CAMK2G;CDK6;CDK7;CDK2 GO:0038128| SRC;EGFR GO:0051301| cell division CDK4;CDK1;CDK2;CDK6;CDK7;CDK5 GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1;CDK5 GO:0007099| centriole replication CDK2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:0030154| cell differentiation HCK;CDK6;CAMK2G GO:0006468| protein phosphorylation ABL1;CDK8;SRC;MAP2K2;BCR;EGFR;HCK;MAP2K1;CAMK2G;CDK9;CDK5;CDK7;CDK6;CDK2;LYN;MAP3K2;CDK1;CDK4 GO:1903800| EGFR;MAP2K1;MAP2K2 GO:0032869| cellular response to insulin stimulus CDK4;SRC GO:0030335| positive regulation of cell migration LYN;EGFR GO:0098609| EGFR;SRC GO:0008202| steroid metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;EGFR;HCK GO:0016310| phosphorylation CDK7;CDK5;CDK6;CAMK2G;CDK9;LYN;CDK2;MAP3K2;CDK4;CDK1;ABL1;CDK8;SRC;BCR;MAP2K2;EGFR;HCK;MAP2K1 GO:1900182| SRC;CDK1 GO:0030900| forebrain development SRC;CDK5 GO:0051321| meiotic cell cycle CDK2 GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;LYN GO:0007050| cell cycle arrest MAP2K1;ABL1;CDK7;CDK6 GO:0016572| histone phosphorylation CDK2;CDK1 GO:0007165| signal transduction LYN;CDK6;CDK4;MAP2K1;EGFR;BCR;SRC GO:0051439| regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle CDK2;CDK1 GO:0006887| exocytosis CDK5;HCK GO:0017144| drug metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0006813| potassium ion transport CDK2 GO:0006979| response to oxidative stress ABL1;EGFR GO:2000773| negative regulation of cellular senescence CDK6;ABL1 GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK1;CDK2 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;CDK1;MAP3K2 GO:0006915| apoptotic process ABL1;CDK1;CDK5 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK7;CDK2;CDK1 GO:0018107| peptidyl-threonine phosphorylation CDK1;CDK5;CAMK2G;MAP2K1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;EGFR GO:0016477| cell migration CDK1;CDK5;SRC GO:0014070| response to organic cyclic compound EGFR;UGT1A1;CDK1;LYN GO:0009636| response to toxin LYN;CDK4;CDK1 GO:0031175| neuron projection development LYN;CDK5 GO:0045646| regulation of erythrocyte differentiation LYN;CDK6 GO:0008283| cell proliferation SRC;EGFR;CDK1;CDK7;CDK5;CDK9 GO:0030182| neuron differentiation CDK5;ABL1;MAP2K1 GO:0007049| cell cycle SRC;CDK4;CDK1;CDK2;CDK6;CDK7;CDK5 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;CDK6 GO:0010033| response to organic substance CDK2;UGT1A1;CDK4 GO:0045892| negative regulation of transcription, DNA-dependent CDK5;SRC GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0070301| cellular response to hydrogen peroxide CDK1;ABL1 GO:0010628| positive regulation of gene expression CDK1;SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0060968| regulation of gene silencing CDK2 GO:0046777| protein autophosphorylation LYN;CDK5;CAMK2G;HCK;EGFR;SRC;BCR;ABL1 3952:[DB06616 DB04459] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways GO:0002376| immune system process LYN;SRC;CFD;HCK GO:0045087| innate immune response LYN;HCK;SRC;CFD;ABL1 GO:0002576| platelet degranulation CFD;LYN 3953:[DB06616 DB07101] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07101|PD-0325901 MAP2K1 common genes MAP2K1 common pathways GO:0001932| regulation of protein phosphorylation MAP2K1;LYN GO:0048870| cell motility MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;LYN GO:0048679| regulation of axon regeneration MAP2K1 GO:0060674| placenta blood vessel development MAP2K1 GO:0006935| chemotaxis MAP2K1 GO:0021697| cerebellar cortex formation MAP2K1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2 GO:0007507| heart development MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1 GO:0050772| positive regulation of axonogenesis MAP2K1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1 GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;MAP3K2 GO:0035897| proteolysis in other organism MAP2K2;MAP2K1 GO:0060440| trachea formation MAP2K1 GO:0060425| lung morphogenesis MAP2K1 GO:0060324| face development MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1 GO:0090398| cellular senescence MAP2K1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2 GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:1903800| MAP2K2;MAP2K1 GO:0048538| thymus development ABL1;MAP2K1 GO:0030878| thyroid gland development MAP2K1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0030182| neuron differentiation ABL1;MAP2K1 GO:0030216| keratinocyte differentiation MAP2K1 GO:0060711| labyrinthine layer development MAP2K1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;MAP2K2 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0006928| cellular component movement MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0090170| regulation of Golgi inheritance MAP2K2;MAP2K1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN 3954:[DB06616 DB04754] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug ABCB1;SRC;PNP;LYN 3955:[DB06616 DB03695] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03695|Piritrexim DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 3956:[DB06616 DB01979] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01979|Methyl alpha-D-mannoside MBL2 common genes common pathways GO:0050766| positive regulation of phagocytosis BCR;MBL2 GO:0006979| response to oxidative stress ABL1;MBL2 GO:0002376| immune system process LYN;MBL2;SRC;HCK GO:0045087| innate immune response MBL2;LYN;ABL1;HCK;SRC 3957:[DB06616 DB02845] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02845|Methylphosphinic Acid BCHE;ACHE;BCHE common genes common pathways GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;ABL1;HCK;SRC GO:0042493| response to drug ABCB1;SRC;BCHE;LYN GO:0006260| DNA replication ACHE;CDK2 GO:0008283| cell proliferation SRC;ACHE GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN 3958:[DB06616 DB00915] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0048678| response to axon injury LYN;DRD2 GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0007399| nervous system development CAMK2G;CHRNA3 GO:0006281| DNA repair CDK2;ABL1;CHRNA4 GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;LYN;CDK2 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;DRD2 GO:0055114| oxidation-reduction process MAOB;CYP3A4;CYP2C8 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;LYN GO:0042493| response to drug DRD2;SRC;ABCB1;LYN;MAOB GO:0006816| calcium ion transport GRIN3A;CAMK2G;CHRNA4;CHRNA7 GO:0007165| signal transduction LYN;MAP2K1;BCR;CHRNA4;CHRNA3;SRC;DRD2;CHRNA7 GO:0030900| forebrain development SRC;DRD2 GO:0006979| response to oxidative stress ABL1;CHRNA4 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;DRD2;CHRNA7;ABL1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0000187| activation of MAPK activity CHRNA7;MAP2K2;MAP2K1;MAP3K2 GO:0009636| response to toxin DRD2;DDC;MAOB;LYN GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0030336| negative regulation of cell migration BCR;DRD2 3959:[DB06616 DB02877] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02877|Arotinoid acid RARB common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;RARB;MAP2K1 GO:0007165| signal transduction LYN;RARB;MAP2K1;SRC;BCR GO:0006355| regulation of transcription, DNA-dependent ABL1;RARB GO:0043066| negative regulation of apoptotic process HCK;RARB;SRC GO:0043065| positive regulation of apoptotic process RARB;SRC;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;RARB GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARB;CDK2 3960:[DB06616 DB08454] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CAMK1D;CDK2;LYN GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CAMK1D;LYN;CDK2 GO:0050766| positive regulation of phagocytosis BCR;CAMK1D GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CAMK1D GO:0007399| nervous system development CAMK2G;CAMK1D GO:0035556| intracellular signal transduction LYN;CAMK1D;CAMK2G;BCR;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;CAMK1D GO:0043065| positive regulation of apoptotic process ABL1;SRC;CAMK1D GO:0018105| peptidyl-serine phosphorylation CAMK2G;CAMK1D;CDK2;SRC GO:0010976| positive regulation of neuron projection development LYN;CAMK1D GO:0006954| inflammatory response CAMK1D;LYN;HCK 3961:[DB06616 DB07469] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07469|(3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways GO:0008360| regulation of cell shape HCK;MYH14 3962:[DB06616 DB06706] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;ADRA1A;BCR GO:0042493| response to drug SRC;ADRA1A;ABCB1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction MAP2K1;BCR;SRC;ADRA1A;LYN GO:0009636| response to toxin LYN;SLC18A2 GO:0006915| apoptotic process ABL1;ADRA1A GO:0055085| transmembrane transport SLC18A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;ADRA1A;SRC;MAP2K2;MAP2K1 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN 3963:[DB06616 DB02373] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02373|Adenosine Monotungstate FHIT common genes common pathways GO:0006915| apoptotic process ABL1;FHIT GO:0006355| regulation of transcription, DNA-dependent ABL1;FHIT 3964:[DB06616 DB11792] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP3A43;CYP3A5;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP3A5;CYP2C8 3965:[DB06616 DB03856] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03856|L-Eflornithine ODC1 common genes common pathways GO:0009615| response to virus ODC1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;ODC1;HCK 3966:[DB06616 DB01120] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC8 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;VEGFA GO:0045785| positive regulation of cell adhesion VEGFA;SRC GO:0032868| response to insulin stimulus ABCC8;LYN GO:0010628| positive regulation of gene expression VEGFA;SRC;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;VEGFA GO:0010595| positive regulation of endothelial cell migration VEGFA;ABL1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2C9 GO:0030335| positive regulation of cell migration LYN;VEGFA GO:0071456| cellular response to hypoxia SRC;VEGFA GO:0030154| cell differentiation CAMK2G;VEGFA;HCK GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0006813| potassium ion transport ABCC8;CDK2 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0097267| CYP2C9;CYP2C19;CYP2C8 GO:0007165| signal transduction MAP2K1;BCR;SRC;ABCC8;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4;CYP2C9 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;VEGFA GO:0042493| response to drug ABCC8;LYN;SRC;ABCB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;VEGFA GO:0001934| positive regulation of protein phosphorylation ABL1;VEGFA;LYN GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2C9;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;VEGFA GO:0031954| positive regulation of protein autophosphorylation VEGFA;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;VEGFA GO:0032496| response to lipopolysaccharide BCR;ABCC8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein VEGFA;LYN GO:0007498| mesoderm development VEGFA;HCK GO:0007275| multicellular organismal development VEGFA;CDK2;CAMK2G GO:0008284| positive regulation of cell proliferation CDK2;LYN;VEGFA;HCK GO:0002576| platelet degranulation ALB;LYN;VEGFA GO:0048010| vascular endothelial growth factor receptor signaling pathway VEGFA;SRC GO:0051272| positive regulation of cellular component movement LYN;VEGFA GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB;VEGFA GO:0042327| positive regulation of phosphorylation VEGFA;LYN GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C19;CYP2C8 GO:0007399| nervous system development VEGFA;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;CDK2 GO:0008360| regulation of cell shape VEGFA;HCK GO:0006629| lipid metabolic process CYP2C9;CYP3A4 3967:[DB06616 DB07339] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process NQO2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;NQO2;CYP2C8 3968:[DB06616 DB06471] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06471|Naxifylline ADORA1 common genes common pathways GO:0008285| negative regulation of cell proliferation ADORA1;LYN;MAP2K1 GO:0000186| activation of MAPKK activity MAP3K2;ADORA1 GO:0007165| signal transduction LYN;ADORA1;MAP2K1;BCR;SRC GO:0006909| phagocytosis ADORA1;HCK;ABL1 GO:0050728| negative regulation of inflammatory response ADORA1;BCR GO:0006954| inflammatory response LYN;ADORA1;HCK GO:0043066| negative regulation of apoptotic process ADORA1;HCK;SRC GO:0007399| nervous system development CAMK2G;ADORA1 3969:[DB06616 DB00423] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00423|Methocarbamol CA1 common genes common pathways 3970:[DB06616 DB02776] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02776|1-Hexadecanosulfonic Acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response LYN;FABP4;HCK GO:0045892| negative regulation of transcription, DNA-dependent FABP4;SRC 3971:[DB06616 DB06726] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction ADRB2;LYN;ADRB3;MAP2K1;BCR;ADRB1;SRC GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0045453| bone resorption ADRB2;SRC GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC 3972:[DB06616 DB01933] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PDPK1;SRC GO:0035556| intracellular signal transduction CAMK2G;PDPK1;LYN;BCR;SRC GO:0043304| regulation of mast cell degranulation LYN;PDPK1 GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;PDPK1;CDK2 GO:0032148| activation of protein kinase B activity PDPK1;SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;PDPK1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;ABL1 GO:0030036| actin cytoskeleton organization PDPK1;BCR;ABL1 GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;PDPK1;LYN;CDK2 GO:0031295| T cell costimulation SRC;PDPK1;LYN GO:0030168| platelet activation SRC;PDPK1;LYN GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;PDPK1;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0032869| cellular response to insulin stimulus PDPK1;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0016477| cell migration SRC;PDPK1 GO:0038095| LYN;PDPK1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;PDPK1 GO:0046777| protein autophosphorylation CAMK2G;PDPK1;LYN;SRC;BCR;HCK;ABL1 3973:[DB06616 DB08365] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08365|8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide WEE1 common genes common pathways GO:0006468| protein phosphorylation WEE1;LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;WEE1;LYN;CDK2;MAP3K2 GO:0000086| G2/M transition of mitotic cell cycle WEE1;CDK2;ABCB1 GO:0007049| cell cycle CDK2;WEE1;SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;WEE1 GO:0051726| regulation of cell cycle WEE1;ABL1;SRC;BCR GO:0000278| mitotic cell cycle WEE1;ABL1 GO:0000082| G1/S transition of mitotic cell cycle CDK2;WEE1;CAMK2G GO:0051301| cell division WEE1;CDK2 3974:[DB06616 DB03606] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;PDE4B;SRC;BCR;PDE4D GO:0050900| leukocyte migration SRC;PDE4B;PDE4D;LYN GO:0007165| signal transduction SRC;BCR;MAP2K1;PDE4B;PDE4D;LYN 3975:[DB06616 DB11477] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0000187| activation of MAPK activity MAP3K2;ADRA2B;MAP2K2;MAP2K1 GO:0007165| signal transduction BCR;SRC;MAP2K1;ADRA2A;ADRA2C;ADRA2B;LYN GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0030168| platelet activation ADRA2C;LYN;ADRA2B;ADRA2A;SRC GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;LYN;CDK2 GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2B;ADRA2C GO:0007265| Ras protein signal transduction CDK2;ADRA2A 3976:[DB06616 DB00244] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;PPARG;LYN GO:0009636| response to toxin CHUK;LYN GO:0043200| response to amino acid stimulus CHUK;LYN GO:0038095| LYN;IKBKB;CHUK GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;LYN;MAP2K1 GO:0010033| response to organic substance PTGS2;PPARG;CDK2;CHUK GO:0034614| cellular response to reactive oxygen species CHUK;SRC GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;CHUK;BCR;MAP2K2;ABL1;MAP3K2;IKBKB;LYN;CDK2;CAMK2G GO:0034605| cellular response to heat LYN;PTGS2 GO:0016310| phosphorylation HCK;MAP2K1;CHUK;SRC;MAP2K2;BCR;ABL1;MAP3K2;IKBKB;LYN;CDK2;CAMK2G GO:0070542| response to fatty acid SRC;PTGS2 GO:0007165| signal transduction PPARG;LYN;SRC;BCR;MAP2K1 GO:0006979| response to oxidative stress ABL1;PTGS1;MPO;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;MPO;ALOX5;CYP3A4;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;IKBKB;CDK2;PPARG;MAP2K1;CHUK;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0042493| response to drug SRC;CHUK;ABCB1;PPARG;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response LYN;IKBKB;PTGS2;ALOX5;PTGS1;CHUK;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CHUK;IKBKB GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;IKBKB;CHUK;SRC GO:0032496| response to lipopolysaccharide PTGS2;MPO;BCR;CHUK GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4;PTGS2;PTGS1 GO:0045087| innate immune response ABL1;CHUK;SRC;HCK;PPARG;LYN;IKBKB GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0007507| heart development PPARG;MAP2K1 GO:0009612| response to mechanical stimulus PPARG;MPO;SRC GO:0043066| negative regulation of apoptotic process IKBKB;PTGS2;HCK;SRC;MPO GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0018105| peptidyl-serine phosphorylation SRC;CHUK;CAMK2G;IKBKB;CDK2 GO:0009615| response to virus SRC;CHUK;IKBKB GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2;PPARG GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 3977:[DB06616 DB03977] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;CALM1 GO:0038095| LYN;CALM1 GO:0006470| protein dephosphorylation CYCS;CAMK2G GO:0055085| transmembrane transport ABCB1;CALM1 GO:0006915| apoptotic process ABL1;CYCS GO:0031954| positive regulation of protein autophosphorylation CALM1;SRC GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2;CALM1 GO:0055114| oxidation-reduction process CYCS;CYP3A4;CYP2C8 GO:0002576| platelet degranulation CALM1;LYN GO:0034599| cellular response to oxidative stress ABL1;CYCS 3978:[DB06616 DB00070] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00070|Hyaluronidase TGFB1;ALB common genes common pathways GO:0001933| negative regulation of protein phosphorylation LYN;TGFB1 GO:0042127| regulation of cell proliferation TGFB1;SRC;ABL1 GO:0050777| negative regulation of immune response LYN;TGFB1 GO:0071260| cellular response to mechanical stimulus MAP3K2;TGFB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TGFB1;CDK2 GO:0007507| heart development TGFB1;MAP2K1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;TGFB1;MAP3K2 GO:2000249| regulation of actin cytoskeleton reorganization TGFB1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus TGFB1;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;TGFB1;HCK GO:0002576| platelet degranulation ALB;TGFB1;LYN GO:0043065| positive regulation of apoptotic process TGFB1;ABL1;SRC GO:0008284| positive regulation of cell proliferation TGFB1;LYN;CDK2;HCK GO:0001934| positive regulation of protein phosphorylation ABL1;TGFB1;LYN GO:0050900| leukocyte migration LYN;TGFB1;SRC GO:0007173| epidermal growth factor receptor signaling pathway TGFB1;ABL1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;TGFB1;CDK2;MAP2K1;SRC;MAP2K2 GO:0042493| response to drug SRC;ABCB1;LYN;TGFB1 GO:0014003| oligodendrocyte development LYN;TGFB1 GO:0010629| negative regulation of gene expression TGFB1;MAP2K1;MAP2K2 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;TGFB1 GO:0051897| positive regulation of protein kinase B signaling cascade TGFB1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;TGFB1;LYN GO:0006954| inflammatory response HCK;LYN;TGFB1 GO:0002513| tolerance induction to self antigen LYN;TGFB1 GO:0001843| neural tube closure TGFB1;ABL1 GO:0045930| negative regulation of mitotic cell cycle ABL1;TGFB1 GO:1903800| TGFB1;MAP2K2;MAP2K1 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;TGFB1;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0030335| positive regulation of cell migration LYN;TGFB1 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;TGFB1;SRC GO:1900182| TGFB1;SRC GO:0007050| cell cycle arrest TGFB1;MAP2K1;ABL1 GO:0022408| negative regulation of cell-cell adhesion ABL1;TGFB1 GO:0006915| apoptotic process TGFB1;ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;TGFB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TGFB1;MAP2K2;SRC;MAP2K1;ABL1 GO:0016477| cell migration TGFB1;SRC GO:0014070| response to organic cyclic compound LYN;TGFB1 GO:0008283| cell proliferation TGFB1;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;TGFB1 GO:0010033| response to organic substance CDK2;TGFB1 GO:0045892| negative regulation of transcription, DNA-dependent TGFB1;SRC GO:0043406| positive regulation of MAP kinase activity TGFB1;SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1;TGFB1 3979:[DB06616 DB00274] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A2;SLC15A1 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0002576| platelet degranulation LYN;ALB 3980:[DB06616 DB02255] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02255|GM6001 ADAM28;ACAN common genes common pathways GO:0007155| cell adhesion ACAN;ABL1;HCK;SRC GO:0007417| central nervous system development SRC;ACAN;LYN 3981:[DB06616 DB06468] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0010447| response to acidity SLC9A1;SRC GO:0016477| cell migration SRC;SLC9A1 GO:0014070| response to organic cyclic compound SLC9A1;LYN GO:0055085| transmembrane transport SLC9A1;ABCB1 GO:0006979| response to oxidative stress ABL1;MPO GO:1902533| SLC9A1;SRC GO:0030154| cell differentiation CAMK2G;HCK;SLC9A1 GO:0032869| cellular response to insulin stimulus SLC9A1;SRC GO:0071456| cellular response to hypoxia SRC;SLC9A1 GO:0055114| oxidation-reduction process CYP2C8;MPO;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;MPO;HCK;SLC9A1 GO:0009612| response to mechanical stimulus MPO;SRC GO:0043065| positive regulation of apoptotic process SRC;SLC9A1;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;SLC9A1 GO:0032496| response to lipopolysaccharide BCR;MPO GO:0051259| protein oligomerization CAMK2G;SLC9A1 3982:[DB06616 DB07638] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007165| signal transduction LYN;ESR1;ESR2;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ESR1;MAP3K2;ESR2;MAP2K1;SRC;MAP2K2 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 3983:[DB06616 DB06833] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESRRA;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;ESRRA;MAP3K2;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;CDK2 GO:0042127| regulation of cell proliferation ABL1;ESRRA;SRC 3984:[DB06616 DB13932] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13932|Voretigene Neparvovec RPE65 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;RPE65;CYP3A4 3985:[DB06616 DB07967] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07967|9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 3986:[DB06616 DB06358] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06358|Iclaprim DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 3987:[DB06616 DB02306] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 3988:[DB06616 DB09276] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09276|Sodium aurothiomalate UGT1A1 common genes common pathways GO:0014070| response to organic cyclic compound LYN;UGT1A1 GO:0010033| response to organic substance UGT1A1;CDK2 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0042493| response to drug SRC;ABCB1;LYN;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;BCR GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 3989:[DB06616 DB00689] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00689|Cephaloglycin SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A5 3990:[DB06616 DB08089] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08089|LGD-2226 AR common genes common pathways GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction BCR;SRC;MAP2K1;AR;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation SRC;AR GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0051259| protein oligomerization AR;CAMK2G GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;AR;HCK GO:0042327| positive regulation of phosphorylation AR;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;AR;MAP3K2;CDK2 3991:[DB06616 DB01044] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 3992:[DB06616 DB04012] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways GO:0001933| negative regulation of protein phosphorylation LYN;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;FKBP1A GO:0019221| cytokine-mediated signaling pathway FKBP1A;HCK GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FKBP1A 3993:[DB06616 DB02557] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02557|Phosphoramidon MME;KEL common genes common pathways 3994:[DB06616 DB04281] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;LYN GO:0055114| oxidation-reduction process DHODH;CYP2C8;CYP3A4 GO:0042493| response to drug DHODH;SRC;ABCB1;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1;DHODH 3995:[DB06616 DB05171] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05171|E-2012 APH1A;PSENEN common genes common pathways GO:0048013| ephrin receptor signaling pathway APH1A;SRC;LYN;PSENEN GO:0043065| positive regulation of apoptotic process PSENEN;SRC;ABL1;APH1A 3996:[DB06616 DB03332] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03332|5,6-Cyclic-Tetrahydropteridine NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;LYN GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 GO:0043542| endothelial cell migration NOS3;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;NOS3 3997:[DB06616 DB00772] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2B6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2B6;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2B6;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2B6;CYP2C8 GO:0042493| response to drug ABCB1;SRC;BCHE;CYP1A2;LYN GO:0008202| steroid metabolic process CYP2C8;CYP2B6;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4;CYP2B6 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0009791| post-embryonic development CYP1A2;ABL1 3998:[DB06616 DB03760] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03760|Dihydrolipoic Acid GCSH;DLAT;PDK3 common genes common pathways GO:0016310| phosphorylation HCK;PDK3;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0071398| cellular response to fatty acid PDK3;SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC;PDK3 3999:[DB06616 DB07135] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0031295| T cell costimulation LYN;DPP4;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0008284| positive regulation of cell proliferation LYN;CDK2;DPP4;HCK GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 4000:[DB06616 DB07525] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;CDK2 GO:0008284| positive regulation of cell proliferation FGFR1;CDK2;LYN;HCK GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;LYN;FGFR1 GO:0042472| inner ear morphogenesis FGFR1;BCR GO:0042127| regulation of cell proliferation ABL1;SRC;FGFR1 GO:0051897| positive regulation of protein kinase B signaling cascade FGFR1;SRC GO:0000165| MAPKKK cascade CAMK2G;FGFR1;MAP2K1;MAP2K2 GO:0010976| positive regulation of neuron projection development LYN;FGFR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;FGFR1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;FGFR1 GO:0007420| brain development BCR;FGFR1 GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;FGFR1;CAMK2G;CDK2;LYN;MAP3K2 GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;FGFR1;CAMK2G;LYN;CDK2 GO:0043406| positive regulation of MAP kinase activity SRC;FGFR1 GO:0046777| protein autophosphorylation LYN;CAMK2G;FGFR1;HCK;SRC;BCR;ABL1 GO:0016477| cell migration FGFR1;SRC 4001:[DB06616 DB06993] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion DPP4;ABL1;SRC;HCK GO:0008284| positive regulation of cell proliferation HCK;DPP4;LYN;CDK2 GO:0031295| T cell costimulation SRC;LYN;DPP4 4002:[DB06616 DB05667] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05667|Levoketoconazole CYP11B1;CYP51A1 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP51A1;CYP11B1 GO:0006629| lipid metabolic process CYP11B1;CYP51A1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP51A1;CYP11B1;CYP2C8 4003:[DB06616 DB06184] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06184|AEG35156 XIAP common genes common pathways GO:0006915| apoptotic process XIAP;ABL1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway XIAP;SRC GO:0042127| regulation of cell proliferation ABL1;SRC;XIAP GO:0043066| negative regulation of apoptotic process HCK;SRC;XIAP GO:0050727| regulation of inflammatory response HCK;LYN;XIAP GO:0006974| response to DNA damage stimulus CDK2;LYN;XIAP;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;XIAP 4004:[DB06616 DB02919] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 4005:[DB06616 DB01131] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9;CYP3A4;DHFR;CYP2C8;CYP2C19;CYP2D6 GO:0042493| response to drug ABCB1;SRC;CYP2E1;LYN GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C19;CYP2C8 GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2C9;CYP2E1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2E1;CYP2D6;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9;CYP2E1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP2C9;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C9;CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4;CYP2C9 4006:[DB06616 DB07141] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4;CYP2C8 4007:[DB06616 DB05078] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05078|AER001 IL4R;IL13RA2 common genes common pathways GO:0042127| regulation of cell proliferation IL4R;SRC;ABL1 GO:0019221| cytokine-mediated signaling pathway IL4R;IL13RA2;HCK GO:0002376| immune system process LYN;IL4R;HCK;SRC GO:0007165| signal transduction IL13RA2;LYN;IL4R;MAP2K1;BCR;SRC 4008:[DB06616 DB00572] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0006816| calcium ion transport CHRNA4;CAMK2G;CHRNB2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRM1;HCK GO:0009615| response to virus CHRM2;SRC GO:0006281| DNA repair CHRNA4;ABL1;CDK2 GO:0007399| nervous system development CHRM1;CAMK2G;CHRM2;CHRM3 GO:0008283| cell proliferation CHRM4;SRC;CHRM1;CHRM3;CHRM5 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0006464| protein modification process CHRM3;CHRM1;ABL1 GO:0006810| transport ABCB11;ABCB1 GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0007165| signal transduction CHRM5;CHRNB2;CHRM3;CHRM1;LYN;CHRM2;BCR;SRC;CHRNA4;MAP2K1;CHRM4 4009:[DB06616 DB05332] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05332|Romiplostim MPL common genes common pathways GO:0019221| cytokine-mediated signaling pathway MPL;HCK GO:0008283| cell proliferation MPL;SRC 4010:[DB06616 DB05339] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05339|MN-305 HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation CDK2;LYN;HTR1A;HCK GO:0007165| signal transduction LYN;HTR1A;MAP2K1;SRC;BCR GO:0008283| cell proliferation SRC;HTR1A 4011:[DB06616 DB00598] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00598|Labetalol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP2C19 common genes common pathways GO:0007275| multicellular organismal development ADRA1B;CDK2;CAMK2G;ADRA1D GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0035556| intracellular signal transduction BCR;SRC;ADRA1A;ADRA1B;LYN;CAMK2G GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;ADRA1D;LYN;CDK2 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0042493| response to drug LYN;SRC;ADRA1A;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ABL1;ADRA1B GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;CYP2C19 GO:0007165| signal transduction ADRB1;SRC;ADRA1A;BCR;MAP2K1;ADRA1B;ADRA1D;LYN;ADRB2 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0045453| bone resorption ADRB2;SRC GO:0006915| apoptotic process ABL1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;ADRA1A;MAP2K1 GO:0008283| cell proliferation ADRA1D;ADRA1B;SRC GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 4012:[DB06616 DB07036] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;MAP2K2;SRC;MAP2K1;CDK2;MAP3K2 GO:0007165| signal transduction ESR2;SRC;BCR;MAP2K1;LYN 4013:[DB06616 DB00415] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0043114| regulation of vascular permeability SRC;TEK;BCR GO:0001934| positive regulation of protein phosphorylation LYN;TEK;ABL1 GO:0050900| leukocyte migration LYN;SLC16A1;SRC;TEK GO:0000165| MAPKKK cascade MAP2K2;TEK;MAP2K1;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TEK GO:0034446| substrate adhesion-dependent cell spreading TEK;SRC;ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization ABL1;TEK;HCK GO:0050728| negative regulation of inflammatory response TEK;BCR GO:0051259| protein oligomerization TEK;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;TEK;MAP2K2;BCR;LYN GO:0051894| positive regulation of focal adhesion assembly ABL1;TEK GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0007507| heart development TEK;MAP2K1 GO:0035556| intracellular signal transduction BCR;TEK;SRC;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process HCK;TEK;SRC;ALB GO:0002576| platelet degranulation LYN;ALB GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport SLC15A1;SLC22A5;SLC15A2;ABCB1;SLC16A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;TEK;MAP2K2;MAP2K1;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis TEK;ABL1 GO:0010033| response to organic substance TEK;CDK2 GO:0060216| definitive hemopoiesis BCR;TEK GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;BCR;TEK;SRC;ABL1 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;TEK;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity TEK;SRC;LYN GO:0043434| response to peptide hormone stimulus LYN;TEK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;TEK;HCK GO:0010595| positive regulation of endothelial cell migration ABL1;TEK GO:0016310| phosphorylation BCR;MAP2K2;TEK;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:1902533| TEK;SRC GO:0007165| signal transduction LYN;MAP2K1;SRC;TEK;BCR 4014:[DB06616 DB00110] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0050766| positive regulation of phagocytosis FCGR2B;BCR GO:0030889| negative regulation of B cell proliferation LYN;FCGR2B GO:0002376| immune system process C1R;C1QB;LYN;C1QC;C1QA;HCK;SRC;FCGR1A;FCGR2A GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;HCK;FCGR1A GO:0007165| signal transduction FCGR2C;FCGR2B;LYN;SRC;BCR;MAP2K1;FCGR1A GO:1901216| ABL1;FCGR2B GO:0006954| inflammatory response HCK;LYN;FCGR2B GO:0016032| viral reproduction LYN;FCGR2B;HCK;SRC GO:0038096| FCGR3A;FCGR2B;LYN;SRC;HCK;ABL1;FCGR2A;FCGR1A GO:0045087| innate immune response SRC;HCK;C1QA;ABL1;FCGR1A;C1QB;C1R;C1QC;LYN GO:0050777| negative regulation of immune response LYN;FCGR2B 4015:[DB06616 DB01094] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;SOAT1;CYP3A4;SOAT2;MTTP GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCG2;SRC;ABCB1;LYN;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0008202| steroid metabolic process CYP2C8;SOAT2;CYP3A4;SOAT1;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 4016:[DB06616 DB05139] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05139|CR002 PDGFD common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PDGFD GO:0071560| cellular response to transforming growth factor beta stimulus PDGFD;SRC GO:0048008| platelet-derived growth factor receptor signaling pathway PDGFD;BCR;SRC;ABL1 GO:0007275| multicellular organismal development CDK2;CAMK2G;PDGFD GO:0031954| positive regulation of protein autophosphorylation SRC;PDGFD GO:0036120| SRC;PDGFD GO:0030335| positive regulation of cell migration LYN;PDGFD GO:0043406| positive regulation of MAP kinase activity PDGFD;SRC GO:0070301| cellular response to hydrogen peroxide PDGFD;ABL1 GO:0007596| blood coagulation PDGFD;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;PDGFD 4017:[DB06616 DB11275] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;SRC;DRD1;LYN;DRD3 GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0048678| response to axon injury DRD2;LYN GO:0035556| intracellular signal transduction BCR;DRD2;SRC;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation HCK;DRD3;LYN;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DRD3 GO:0009636| response to toxin LYN;DRD2 GO:0000187| activation of MAPK activity DRD4;MAP3K2;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;DRD2;SRC;MAP2K1;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;DRD1 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0030900| forebrain development DRD2;SRC GO:1903351| ABL1;DRD1 GO:0007165| signal transduction DRD4;LYN;DRD3;DRD1;BCR;SRC;DRD2;MAP2K1;DRD5 4018:[DB06616 DB00650] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A8;ABCB1 4019:[DB06616 DB09026] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09026|Aliskiren REN;CYP3A4 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0010033| response to organic substance REN;CDK2 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ABCB1;REN;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0032496| response to lipopolysaccharide REN;BCR GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 4020:[DB06616 DB07028] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07028|(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance CDK2;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 4021:[DB06616 DB04738] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04738|Motuporin PPP1CC common genes common pathways GO:0007049| cell cycle CDK2;PPP1CC;SRC GO:0030182| neuron differentiation PPP1CC;ABL1;MAP2K1 GO:0006470| protein dephosphorylation CAMK2G;PPP1CC GO:0051301| cell division PPP1CC;CDK2 4022:[DB06616 DB01247] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01247|Isocarboxazid MAOA;MAOB common genes common pathways GO:0009636| response to toxin MAOB;LYN GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0042493| response to drug LYN;MAOB;SRC;ABCB1 GO:0055114| oxidation-reduction process MAOA;MAOB;CYP3A4;CYP2C8 4023:[DB06616 DB08449] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08449|2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC 4024:[DB06616 DB07542] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07542|5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOBUTYL-HEXANOIC ACID CTSD common genes common pathways GO:0006914| autophagy CTSD;ABL1 4025:[DB06616 DB05001] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05001|PSN9301 DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0008284| positive regulation of cell proliferation HCK;DPP4;CDK2;LYN GO:0007155| cell adhesion DPP4;ABL1;HCK;SRC GO:0043542| endothelial cell migration ABL1;DPP4 4026:[DB06616 DB11973] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11973|Tesevatinib EGF;EPHB4;ERBB2 common genes common pathways GO:0008283| cell proliferation SRC;ERBB2 GO:0000187| activation of MAPK activity MAP3K2;EGF;MAP2K1;MAP2K2 GO:0045785| positive regulation of cell adhesion ERBB2;SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1;ERBB2;EGF GO:0046777| protein autophosphorylation CAMK2G;EPHB4;LYN;SRC;BCR;HCK;ABL1;ERBB2 GO:0048013| ephrin receptor signaling pathway LYN;EPHB4;SRC GO:0043406| positive regulation of MAP kinase activity SRC;ERBB2;EGF GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;ERBB2;LYN;EPHB4 GO:0030335| positive regulation of cell migration EGF;LYN GO:0043547| positive regulation of GTPase activity BCR;ERBB2 GO:0016310| phosphorylation MAP3K2;EPHB4;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;ERBB2 GO:0000186| activation of MAPKK activity MAP3K2;EGF GO:0006468| protein phosphorylation ABL1;ERBB2;HCK;MAP2K1;SRC;BCR;MAP2K2;EPHB4;LYN;CDK2;CAMK2G;MAP3K2 GO:0070372| regulation of ERK1 and ERK2 cascade ERBB2;LYN GO:0007165| signal transduction LYN;EGF;MAP2K1;SRC;BCR;ERBB2 GO:0007173| epidermal growth factor receptor signaling pathway EGF;SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2;EGF GO:0006355| regulation of transcription, DNA-dependent ABL1;ERBB2 GO:0001934| positive regulation of protein phosphorylation LYN;ERBB2;ABL1 GO:0070371| ERK1 and ERK2 cascade EGF;MAP2K2;MAP2K1 GO:0006260| DNA replication CDK2;EGF GO:0051897| positive regulation of protein kinase B signaling cascade SRC;ERBB2;EGF GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;ERBB2;EGF;CAMK2G GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;EGF;ABL1;SRC GO:0038128| ERBB2;SRC;EGF GO:0018108| peptidyl-tyrosine phosphorylation ERBB2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;EGF;LYN;EPHB4 GO:0007275| multicellular organismal development CDK2;EPHB4;CAMK2G GO:0042327| positive regulation of phosphorylation LYN;EGF GO:2000145| regulation of cell motility EGF;ABL1;ERBB2 GO:0008284| positive regulation of cell proliferation HCK;EGF;CDK2;LYN GO:0002576| platelet degranulation LYN;EGF GO:0007399| nervous system development ERBB2;CAMK2G GO:0007507| heart development MAP2K1;ERBB2 GO:0007155| cell adhesion ABL1;HCK;SRC;EPHB4 4027:[DB06616 DB06857] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06857|N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE PLAU common genes common pathways GO:0006935| chemotaxis MAP2K1;PLAU GO:0042127| regulation of cell proliferation PLAU;ABL1;SRC GO:0007596| blood coagulation PLAU;LYN GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;PLAU GO:0030335| positive regulation of cell migration PLAU;LYN 4028:[DB06616 DB13933] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0055114| oxidation-reduction process F8;CYP3A4;CYP2C8 GO:0031667| response to nutrient levels F7;SRC GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC;F7 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC GO:0002576| platelet degranulation LYN;F8 GO:0007596| blood coagulation F8;LYN;F10;F7 GO:0014070| response to organic cyclic compound F7;LYN GO:0030168| platelet activation SRC;F8;LYN GO:0030335| positive regulation of cell migration F7;LYN;F10 GO:0009725| response to hormone stimulus F7;LYN 4029:[DB06616 DB04796] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04796|Inecalcitol VDR common genes common pathways GO:0010628| positive regulation of gene expression VDR;MAP2K1;SRC GO:0008285| negative regulation of cell proliferation VDR;MAP2K1;LYN GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC GO:0007165| signal transduction VDR;MAP2K1;BCR;SRC;LYN GO:0006816| calcium ion transport VDR;CAMK2G GO:0006355| regulation of transcription, DNA-dependent VDR;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VDR GO:0007275| multicellular organismal development VDR;CDK2;CAMK2G 4030:[DB06616 DB02930] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02930|Adenosine 5'-[γ-thio]triphosphate BST1;SYN1;BCKDK;PFKFB1;PMS2;recA;recA;recA;recQ common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;BST1;LYN;CDK2 GO:0050727| regulation of inflammatory response LYN;BST1;HCK GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;PMS2 GO:0006281| DNA repair PMS2;CDK2;ABL1 GO:0042493| response to drug ABCB1;SRC;LYN;PMS2 GO:0006298| mismatch repair PMS2;ABL1 GO:0016310| phosphorylation PFKFB1;CAMK2G;CDK2;LYN;MAP3K2;ABL1;BCKDK;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0006468| protein phosphorylation ABL1;BCKDK;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0032956| regulation of actin cytoskeleton organization BST1;ABL1 GO:0007165| signal transduction BST1;BCR;SRC;MAP2K1;LYN GO:0032868| response to insulin stimulus LYN;PFKFB1 4031:[DB06616 DB13948] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0016032| viral reproduction HCK;SRC;HTR2A;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0042493| response to drug LYN;HTR2A;SRC;ABCB1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR2A GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;HTR2A GO:0007165| signal transduction LYN;HTR2A;SRC;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 4032:[DB06616 DB08574] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 4033:[DB06616 DB07768] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0006629| lipid metabolic process AKR1C2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;AKR1C1 GO:0008284| positive regulation of cell proliferation HCK;AKR1C2;CDK2;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;AKR1C2 GO:0055114| oxidation-reduction process CYP2C8;AKR1C2;CYP3A4;AKR1C1 GO:0008202| steroid metabolic process AKR1C2;CYP2C8;CYP3A4 4034:[DB06616 DB01053] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport SLC22A11;SLCO2B1;SLCO4A1;ABCB1;SLC22A8;SLC15A2;SLC22A5;SLCO1B1;SLC15A1;SLC22A4;SLCO3A1;SLC22A6 GO:0009636| response to toxin LYN;SLC22A8 4035:[DB06616 DB00350] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00350|Minoxidil KCNJ1;PTGS1;REN;UGT1A1 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0006813| potassium ion transport KCNJ1;CDK2 GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0014070| response to organic cyclic compound LYN;UGT1A1 GO:0010033| response to organic substance UGT1A1;REN;CDK2 GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;REN;BCR GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;SRC;REN;LYN;UGT1A1 GO:0006954| inflammatory response LYN;HCK;PTGS1 4036:[DB06616 DB06830] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 4037:[DB06616 DB03247] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RPS6KA4;ABL1 GO:0042738| exogenous drug catabolic process NOS1;CYP3A4;CYP2C8 GO:0042493| response to drug LYN;ABCB1;SRC;POR;DHODH GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;NOS1;CDK2;MAP2K2;SRC;MAP2K1 GO:0055114| oxidation-reduction process DPYD;POR;HAO2;PNPO;DHODH;CYP2C8;HAO1;CYP3A4;NOS1;BLVRB GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;POR GO:0006954| inflammatory response LYN;RPS6KA4;HCK GO:0042127| regulation of cell proliferation ABL1;SRC;SGK1 GO:0018105| peptidyl-serine phosphorylation SGK1;SRC;CDK2;CAMK2G GO:0043065| positive regulation of apoptotic process DHODH;ABL1;SRC GO:0043066| negative regulation of apoptotic process HCK;POR;SRC GO:0006805| xenobiotic metabolic process CYP3A4;POR;CYP2C8 GO:0035556| intracellular signal transduction CAMK2G;LYN;RPS6KA4;SGK1;BCR;SRC GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;SGK1;MAP2K1 GO:0006974| response to DNA damage stimulus CDK2;LYN;ABL1;SGK1 GO:0014070| response to organic cyclic compound LYN;DHODH GO:0006915| apoptotic process RFK;SGK1;ABL1 GO:0071375| cellular response to peptide hormone stimulus SRC;POR GO:0016310| phosphorylation MAP2K2;SGK1;BCR;SRC;MAP2K1;HCK;RPS6KA4;ABL1;RFK;MAP3K2;CAMK2G;CDK2;LYN GO:0006468| protein phosphorylation SRC;BCR;SGK1;MAP2K2;HCK;MAP2K1;ABL1;RPS6KA4;MAP3K2;CAMK2G;LYN;CDK2 GO:0006979| response to oxidative stress ABL1;HAO1 GO:0016572| histone phosphorylation CDK2;RPS6KA4 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;SGK1 4038:[DB06616 DB03907] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0042493| response to drug LYN;COMT;SRC;ABCB1 GO:0032496| response to lipopolysaccharide BCR;COMT GO:0014070| response to organic cyclic compound COMT;LYN 4039:[DB06616 DB06354] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;GABBR1 GO:0006810| transport ABCB1;GRIK1 GO:0007417| central nervous system development LYN;SRC;GRIK1 GO:0055085| transmembrane transport GRIK1;ABCB1 GO:0007399| nervous system development GRIK1;CAMK2G 4040:[DB06616 DB12773] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12773|Sifalimumab IFNA2 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent IFNA2;SRC GO:0007596| blood coagulation IFNA2;LYN GO:0042100| B cell proliferation IFNA2;ABL1 GO:0006915| apoptotic process IFNA2;ABL1 GO:0042327| positive regulation of phosphorylation IFNA2;LYN GO:0045087| innate immune response ABL1;SRC;HCK;LYN;IFNA2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IFNA2 GO:0006954| inflammatory response IFNA2;LYN;HCK GO:0019221| cytokine-mediated signaling pathway IFNA2;HCK GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;IFNA2 GO:0045893| positive regulation of transcription, DNA-dependent IFNA2;MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 4041:[DB06616 DB04893] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04893|AZD3409 FNTB;FNTA common genes common pathways GO:0042127| regulation of cell proliferation ABL1;SRC;FNTB GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FNTA 4042:[DB06616 DB07068] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07068|(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID PTPRB common genes common pathways GO:0006470| protein dephosphorylation CAMK2G;PTPRB 4043:[DB06616 DB04521] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04521|GSHNA GSTA3 common genes common pathways 4044:[DB06616 DB04756] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 4045:[DB06616 DB02018] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02018|Amido Phenyl Pyruvic Acid TPSB2 common genes common pathways 4046:[DB06616 DB11731] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways GO:0051301| cell division TUBB;CDK2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;EGFR GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB;CDK2 GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1;EGFR GO:0038128| EGFR;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;SRC;MAP2K2;EGFR;MAP2K1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;EGFR GO:0038083| HCK;EGFR;SRC;ABL1;LYN GO:0001934| positive regulation of protein phosphorylation EGFR;ABL1;LYN GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process HCK;EGFR;SRC GO:2000145| regulation of cell motility ABL1;EGFR GO:0035556| intracellular signal transduction EGFR;SRC;BCR;LYN;CAMK2G GO:0008284| positive regulation of cell proliferation LYN;CDK2;EGFR;HCK GO:0071260| cellular response to mechanical stimulus EGFR;MAP3K2 GO:0042127| regulation of cell proliferation ABL1;EGFR;SRC GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;EGFR;BCR;MAP2K2;SRC;ABL1;LYN GO:0007275| multicellular organismal development CAMK2G;CDK2;EGFR GO:0006928| cellular component movement TUBB;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;EGFR;BCR;SRC GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0014070| response to organic cyclic compound EGFR;LYN GO:0008283| cell proliferation SRC;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;EGFR GO:0000086| G2/M transition of mitotic cell cycle TUBB;CDK2;ABCB1 GO:0006979| response to oxidative stress EGFR;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;EGFR GO:0007165| signal transduction LYN;MAP2K1;EGFR;BCR;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;EGFR GO:0098609| EGFR;SRC GO:0030335| positive regulation of cell migration LYN;EGFR GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;EGFR;MAP2K1;SRC;MAP2K2;BCR GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle EGFR;ABL1 GO:1903800| MAP2K2;MAP2K1;EGFR GO:0006468| protein phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;EGFR;CAMK2G;CDK2;LYN;MAP3K2 4047:[DB06616 DB04753] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug LYN;PNP;ABCB1;SRC 4048:[DB06616 DB02264] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02264|O2-Sulfo-Glucuronic Acid FGF1;HGF;HS3ST3A1 common genes common pathways GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;HGF;MAP3K2;FGF1 GO:0008283| cell proliferation FGF1;HGF;SRC GO:0043406| positive regulation of MAP kinase activity SRC;FGF1 GO:0030154| cell differentiation HCK;CAMK2G;FGF1 GO:0010595| positive regulation of endothelial cell migration FGF1;ABL1 GO:0034605| cellular response to heat FGF1;LYN GO:0030335| positive regulation of cell migration LYN;FGF1;HGF GO:0007165| signal transduction LYN;FGF1;MAP2K1;SRC;BCR GO:1902533| SRC;FGF1 GO:0001934| positive regulation of protein phosphorylation ABL1;FGF1;LYN GO:0000278| mitotic cell cycle ABL1;HGF GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;HGF GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HGF;ABL1;LYN GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;HGF;SRC GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;HGF;FGF1;CAMK2G GO:0050728| negative regulation of inflammatory response BCR;HGF GO:2000573| positive regulation of DNA biosynthetic process SRC;HGF GO:0018108| peptidyl-tyrosine phosphorylation HGF;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;FGF1 GO:0007275| multicellular organismal development FGF1;CAMK2G;CDK2 GO:0032148| activation of protein kinase B activity FGF1;SRC GO:0008284| positive regulation of cell proliferation HCK;HGF;FGF1;LYN;CDK2 GO:0002576| platelet degranulation LYN;HGF GO:0043066| negative regulation of apoptotic process HGF;HCK;SRC 4049:[DB06616 DB05883] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05883|ABX-PTH PTH common genes common pathways GO:0045453| bone resorption SRC;PTH GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PTH GO:0031667| response to nutrient levels SRC;PTH GO:0042493| response to drug LYN;PTH;ABCB1;SRC 4050:[DB06616 DB08841] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08841|Tyramine SLC22A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A3 GO:0006855| drug transmembrane transport SLC22A3;ABCB1 4051:[DB06616 DB07443] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;DHODH;ABL1 GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0042493| response to drug DHODH;ABCB1;SRC;LYN GO:0014070| response to organic cyclic compound DHODH;LYN 4052:[DB06616 DB07032] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways GO:0007165| signal transduction ESR2;BCR;SRC;MAP2K1;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;ESR2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1 4053:[DB06616 DB09272] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport SLC22A8;SLCO1B1;ABCB1;ABCC2 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;LYN;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0006810| transport ABCB1;ABCC2 GO:0006979| response to oxidative stress ABCC2;ABL1 GO:0007165| signal transduction OPRM1;OPRD1;LYN;BCR;SRC;MAP2K1;OPRK1 GO:0042493| response to drug ABCC2;SRC;ABCB1;LYN GO:0010629| negative regulation of gene expression OPRD1;MAP2K1;MAP2K2 GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G GO:0032496| response to lipopolysaccharide BCR;ABCC2;OPRM1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;OPRK1;ABCC2 4054:[DB06616 DB07625] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07625|4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0006935| chemotaxis MAP2K1;PLAU GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007596| blood coagulation LYN;PLAU GO:0007165| signal transduction PLAU;BCR;SRC;MAP2K1;LYN GO:0030335| positive regulation of cell migration LYN;PLAU 4055:[DB06616 DB00024] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00024|Thyrotropin alfa TSHR common genes common pathways GO:0007165| signal transduction LYN;SRC;BCR;TSHR;MAP2K1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;TSHR GO:0007399| nervous system development CAMK2G;TSHR 4056:[DB06616 DB04871] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes CYP3A4 common pathways GO:0009615| response to virus SRC;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP2C19;CYP3A4;FMO1;CYP2B6;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP1A2;CYP1A1;CYP2B6;CYP2A6 GO:0006082| organic acid metabolic process FMO1;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2;FMO1;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19 GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP1A2 GO:0042493| response to drug HTR2C;SRC;ABCB1;LYN;CYP1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2B6;CYP2A6;CYP1A2;CYP2C8;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4;CYP1A1;FMO1;CYP2A6;CYP2B6 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0007165| signal transduction HTR2C;SRC;BCR;MAP2K1;LYN GO:0017144| drug metabolic process CYP1A2;CYP3A4;FMO1;CYP1A1;CYP2A6;CYP2B6;CYP2D6;CYP2C19;CYP2C8 GO:0097267| CYP1A1;CYP1A2;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance CYP1A2;CYP1A1;CDK2 GO:0008283| cell proliferation SRC;CYP1A1 GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0009636| response to toxin LYN;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;LYN;CYP1A2 GO:0036378| CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;HTR2C;ABL1 4057:[DB06616 DB03616] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03616|Kabiramide C ACTA1 common genes common pathways GO:0009612| response to mechanical stimulus ACTA1;SRC GO:0010628| positive regulation of gene expression ACTA1;SRC;MAP2K1 4058:[DB06616 DB00657] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0006281| DNA repair ABL1;CHRNA4;CDK2 GO:0008284| positive regulation of cell proliferation HCK;CHRNA7;LYN;CDK2 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;LYN GO:0006816| calcium ion transport CHRNA7;CHRNA4;CAMK2G;CHRNB2 GO:0007165| signal transduction CHRNB2;LYN;CHRNA2;MAP2K1;SRC;CHRNA4;BCR;CHRNA7 GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;CHRNA7;MAP2K2;SRC;MAP2K1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1;CHRNA7 4059:[DB06616 DB08844] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport ABCB1;SLC2A9;SLC22A8;SLC22A6 4060:[DB06616 DB01375] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01375|Aluminium monostearate TNNC1;VDAC1;VDAC2;VDAC3 common genes common pathways GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;BCR GO:0055085| transmembrane transport ABCB1;VDAC1;VDAC2;VDAC3 GO:0006915| apoptotic process VDAC1;ABL1 GO:0016032| viral reproduction LYN;SRC;VDAC1;HCK GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;VDAC2 GO:0016236| macroautophagy SRC;VDAC1 4061:[DB06616 DB07945] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07945|5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid FABP4 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent FABP4;SRC GO:0050727| regulation of inflammatory response FABP4;HCK;LYN 4062:[DB06616 DB09110] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09110|Coenzyme M GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;GSR GO:0034599| cellular response to oxidative stress GSR;ABL1 4063:[DB06616 DB00810] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0007165| signal transduction CHRM1;LYN;BCR;SRC;MAP2K1;CHRNA2 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0006464| protein modification process ABL1;CHRM1 GO:0008283| cell proliferation CHRM1;SRC GO:0007399| nervous system development CHRM1;CAMK2G GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CHRM1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 4064:[DB06616 DB08382] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08382|Gosogliptin DPP4 common genes common pathways GO:0031295| T cell costimulation LYN;DPP4;SRC GO:0043542| endothelial cell migration DPP4;ABL1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;DPP4 GO:0007155| cell adhesion ABL1;HCK;SRC;DPP4 4065:[DB06616 DB09460] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;SRC GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0042493| response to drug LYN;SRC;ABCB1;CA9 GO:0010033| response to organic substance CA2;CDK2 4066:[DB06616 DB01405] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LYN;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 4067:[DB06616 DB02613] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0042493| response to drug ABCB1;SRC;DHODH;LYN GO:0006629| lipid metabolic process CYP3A4;PNLIPRP2 GO:0043065| positive regulation of apoptotic process ABL1;DHODH;SRC GO:0014070| response to organic cyclic compound LYN;DHODH 4068:[DB06616 DB13873] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes common pathways GO:0006915| apoptotic process PPARD;ABL1 GO:0032868| response to insulin stimulus LYN;PPARA GO:0014070| response to organic cyclic compound LYN;PPARG GO:0008283| cell proliferation PPARD;SRC GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0010033| response to organic substance CDK2;PPARG;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;PPARD;SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1;PPARD;NR1I2 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0030154| cell differentiation CAMK2G;PPARD;HCK GO:0071456| cellular response to hypoxia SRC;PPARD GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0008202| steroid metabolic process NR1I2;CYP3A4;CYP2C8 GO:0007165| signal transduction LYN;NR1I2;PPARG;MAP2K1;BCR;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;PPARD;MAP3K2;PPARG;PPARA;NR1I2;CDK2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;NR1I2 GO:0042493| response to drug LYN;PPARG;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1I2;PPARG;PPARA;PPARD GO:0050728| negative regulation of inflammatory response BCR;PPARA;PPARD GO:0042127| regulation of cell proliferation SRC;ABL1;PPARD GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4;PPARD GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;CDK2;PPARG;PPARA GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0007507| heart development PPARG;PPARA;PPARD;MAP2K1 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4;CYP2C8 GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043066| negative regulation of apoptotic process PPARD;HCK;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0071222| cellular response to lipopolysaccharide PPARD;SRC;BCR;ABL1 GO:0008284| positive regulation of cell proliferation HCK;PPARD;CDK2;LYN 4069:[DB06616 DB05361] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0008284| positive regulation of cell proliferation F2R;CDK2;LYN;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;F2R GO:0032496| response to lipopolysaccharide BCR;F2R GO:0006954| inflammatory response LYN;F2R;HCK GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;MAP3K2;F2R;CDK2 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;F2R GO:0007165| signal transduction SRC;BCR;MAP2K1;F2R;LYN GO:0000186| activation of MAPKK activity F2R;MAP3K2 GO:0030168| platelet activation F2R;LYN;SRC GO:0007204| elevation of cytosolic calcium ion concentration F2R;ABL1 GO:0043547| positive regulation of GTPase activity BCR;F2R GO:0030335| positive regulation of cell migration LYN;F2R GO:0008285| negative regulation of cell proliferation LYN;F2R;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;F2R GO:0007596| blood coagulation F2R;LYN;SERPINC1 4070:[DB06616 DB08784] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 4071:[DB06616 DB02285] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02285|Protoporphyrin FTL common genes common pathways 4072:[DB06616 DB00038] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00038|Oprelvekin IL11RA common genes common pathways GO:0007165| signal transduction LYN;IL11RA;SRC;BCR;MAP2K1 GO:0019221| cytokine-mediated signaling pathway IL11RA;HCK 4073:[DB06616 DB07249] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07249|N-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine EPHB4 common genes common pathways GO:0046777| protein autophosphorylation CAMK2G;EPHB4;LYN;ABL1;SRC;BCR;HCK GO:0048013| ephrin receptor signaling pathway SRC;EPHB4;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;EPHB4 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;EPHB4;CAMK2G;MAP3K2 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;EPHB4;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0007155| cell adhesion EPHB4;ABL1;SRC;HCK GO:0007275| multicellular organismal development CAMK2G;EPHB4;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;EPHB4;LYN 4074:[DB06616 DB00512] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00512|Vancomycin ALB;ORM1;ORM2 common genes common pathways GO:0006954| inflammatory response LYN;ORM1;HCK GO:0002576| platelet degranulation ALB;ORM2;ORM1;LYN GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC 4075:[DB06616 DB06231] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06231|Caldaret SLC8A1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;SLC8A1 GO:0071456| cellular response to hypoxia SRC;SLC8A1 GO:0055085| transmembrane transport ABCB1;SLC8A1 GO:0034614| cellular response to reactive oxygen species SRC;SLC8A1 GO:0042542| response to hydrogen peroxide SRC;SLC8A1 GO:0042493| response to drug ABCB1;SLC8A1;SRC;LYN GO:0051924| regulation of calcium ion transport SLC8A1;CAMK2G GO:0006816| calcium ion transport SLC8A1;CAMK2G 4076:[DB06616 DB00733] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00733|Pralidoxime ACHE;BCHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0042493| response to drug LYN;BCHE;ABCB1;SRC GO:0006260| DNA replication ACHE;CDK2 GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0007399| nervous system development ACHE;CAMK2G 4077:[DB06616 DB00160] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0042493| response to drug ABAT;ABCB1;SRC;LYN GO:0050900| leukocyte migration SLC7A8;LYN;SRC GO:0050885| neuromuscular process controlling balance ABL1;BCR;AARS GO:0009636| response to toxin LYN;SLC7A8 GO:0055085| transmembrane transport SLC16A10;SLC1A4;ABCB1;SLC36A1 GO:0006810| transport SLC7A8;ABCB1 4078:[DB06616 DB00596] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;LYN;SRC;BCR;MAP2K1 GO:0006915| apoptotic process ABL1;NR3C1 GO:0007049| cell cycle NR3C1;CDK2;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0051301| cell division NR3C1;CDK2 4079:[DB06616 DB07008] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NOS2 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;NOS2 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC 4080:[DB06616 DB00094] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00094|Urofollitropin FSHR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;FSHR;MAP2K2 GO:0001545| primary ovarian follicle growth FSHR;SRC GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;FSHR 4081:[DB06616 DB00189] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug ABCB1;SRC;GABRG3;LYN GO:0007165| signal transduction GABRB3;SRC;BCR;MAP2K1;GABRD;GABRA6;GABRP;LYN;GABRE;GABRQ;GABRB1;GABRA5 GO:0007420| brain development GABRA5;BCR GO:0007417| central nervous system development LYN;GABRA4;SRC GO:0006810| transport ABCB1;GABRB3;GABRG2;GABRA5;GABRB1;GABRA3;GABRA1;GABRA6;GABRA4;GABRB2;GABRD GO:0009791| post-embryonic development ABL1;GABRG2 GO:0009636| response to toxin LYN;GABRB1 4082:[DB06616 DB09395] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09395|Sodium acetate ACSS2 common genes common pathways 4083:[DB06616 DB11639] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC;BMPR1A GO:0007420| brain development BCR;BMPR2 GO:0030154| cell differentiation HCK;BMPR1A;CAMK2G GO:0006468| protein phosphorylation CAMK2G;BMPR1A;CDK2;LYN;BMPR2;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0016310| phosphorylation MAP3K2;BMPR2;CDK2;LYN;CAMK2G;BMPR1A;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0010595| positive regulation of endothelial cell migration BMPR2;ABL1 GO:0023014| signal transduction via phosphorylation event BMPR1A;BMPR2;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;BMPR1A GO:0007399| nervous system development CAMK2G;BMPR1A GO:2000772| regulation of cellular senescence ABL1;BMPR1A GO:0010634| positive regulation of epithelial cell migration SRC;BMPR2 GO:0007507| heart development MAP2K1;BMPR1A GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;BMPR2 GO:0042127| regulation of cell proliferation SRC;ABL1;BMPR2 4084:[DB06616 DB11075] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11075|Hypromellose EPCAM common genes common pathways GO:0050900| leukocyte migration LYN;SRC;EPCAM GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;EPCAM GO:0098609| EPCAM;SRC 4085:[DB06616 DB01366] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01366|Procaterol ADRB2 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC GO:0045453| bone resorption ADRB2;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;ADRB2 4086:[DB06616 DB00385] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00385|Valrubicin TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus CDK2;LYN;TOP2A;ABL1 GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 4087:[DB06616 DB14596] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes CYP3A4 common pathways GO:0051301| cell division CDK2;NR3C1 GO:0031667| response to nutrient levels SRC;PON1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0006629| lipid metabolic process PON1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009636| response to toxin PON1;LYN GO:0006915| apoptotic process NR3C1;ABL1 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0070542| response to fatty acid PON1;SRC GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0007165| signal transduction MAP2K1;BCR;SRC;NR3C1;LYN GO:0008202| steroid metabolic process CYP3A4;CYP2C8 4088:[DB06616 DB01440] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0050900| leukocyte migration SLC16A3;LYN;SRC;SLC16A1 GO:0007165| signal transduction MAP2K1;SRC;BCR;GABRB1;LYN GO:0006810| transport GABRB1;ABCB1 GO:0055085| transmembrane transport SLC16A7;SLC16A3;ABCB1;SLC16A1 GO:0009636| response to toxin LYN;GABRB1 4089:[DB06616 DB00920] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00920|Ketotifen HRH1;PGD common genes common pathways GO:0006954| inflammatory response HRH1;LYN;HCK GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PGD GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0007165| signal transduction LYN;HRH1;MAP2K1;BCR;SRC 4090:[DB06616 DB04207] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04207|N-(5-Amino-5-Carboxypentyl)Glutamic Acid AASS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;AASS;CYP2C8 4091:[DB06616 DB14530] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14530|Chromous sulfate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYB5A;CYP3A4 GO:0002576| platelet degranulation TF;LYN 4092:[DB06616 DB01144] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways GO:2001225| regulation of chloride transport CA7;CA2;ABCB1 GO:0071498| cellular response to fluid shear stress CA2;SRC GO:0006979| response to oxidative stress CA3;ABL1 GO:0010033| response to organic substance CDK2;CA2 4093:[DB06616 DB00558] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00558|Zanamivir NEU2 common genes common pathways GO:0006629| lipid metabolic process NEU2;CYP3A4 4094:[DB06616 DB01623] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;HTR2A;CDK2;LYN GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;DRD2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP1A2 GO:0048678| response to axon injury LYN;DRD2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0001932| regulation of protein phosphorylation LYN;MAP2K1;DRD1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;LYN;ABL1;SRC GO:0016032| viral reproduction HTR2A;LYN;HCK;SRC GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8;CYP2D6 GO:0042493| response to drug CYP1A2;HTR2A;LYN;ABCB1;DRD2;SRC;DRD1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0007165| signal transduction MAP2K1;SRC;DRD2;BCR;DRD1;HTR2A;LYN GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C8 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:1903351| DRD1;ABL1 GO:0030900| forebrain development DRD2;SRC GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C8 GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010628| positive regulation of gene expression DRD1;MAP2K1;SRC GO:0055085| transmembrane transport SLC22A1;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K1;MAP2K2;SRC;DRD2;ABL1 GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0009636| response to toxin DRD2;LYN 4095:[DB06616 DB08168] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways GO:0006915| apoptotic process ABL1;PPIF GO:0070301| cellular response to hydrogen peroxide PPIF;ABL1 GO:0006979| response to oxidative stress ABL1;PPIF GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;HDAC8 GO:0006355| regulation of transcription, DNA-dependent ABL1;HDAC8 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;PPIF GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;MAP2K1;PPIF GO:0043066| negative regulation of apoptotic process HCK;SRC;PPIF 4096:[DB06616 DB13997] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCB5 GO:0036378| CYP3A4 GO:0006855| drug transmembrane transport ABCB5;ABCB1 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A3;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0042908| xenobiotic transport ABCB5;ABCB1 GO:0030154| cell differentiation ABCB5;HCK;CAMK2G GO:0008202| steroid metabolic process CYP2C8;CYP3A4 4097:[DB06616 DB03958] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03958|7-methyl-guanosine-5'-triphosphate-5'-guanosine DCPS common genes common pathways 4098:[DB06616 DB08044] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08044|ABT-341 DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;ABL1;HCK;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation LYN;DPP4;SRC 4099:[DB06616 DB14582] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways GO:0006954| inflammatory response LYN;ORM1;HCK GO:0002576| platelet degranulation LYN;ORM1;ORM2;ALB GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB 4100:[DB06616 DB00691] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0016032| viral reproduction HCK;SRC;ACE2;LYN GO:0001817| regulation of cytokine production ACE2;LYN GO:0042127| regulation of cell proliferation ACE2;ABL1;SRC GO:0050727| regulation of inflammatory response ACE2;LYN;HCK GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 4101:[DB06616 DB02322] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;CCL5 GO:0045785| positive regulation of cell adhesion CCL5;SRC GO:0009636| response to toxin CCL5;LYN GO:0014911| positive regulation of smooth muscle cell migration SRC;CCL5 GO:0043547| positive regulation of GTPase activity CCL5;BCR GO:0030335| positive regulation of cell migration LYN;CCL5 GO:0006887| exocytosis HCK;CCL5 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;CCL5 GO:0006816| calcium ion transport CAMK2G;CCL5 GO:0006954| inflammatory response HCK;CCL5;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;CCL5 GO:0042327| positive regulation of phosphorylation CCL5;LYN GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;CCL5;HCK GO:0009615| response to virus SRC;CCL5 GO:0006935| chemotaxis MAP2K1;CCL5 4102:[DB06616 DB05442] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1;IL1B GO:0009743| response to carbohydrate stimulus IL1B;LYN GO:0019221| cytokine-mediated signaling pathway HCK;IL1B GO:0006954| inflammatory response LYN;IL1B;HCK GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;IL1B GO:0050900| leukocyte migration LYN;SRC;IL1B GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;IL1B;MAP2K1;MAP2K2;SRC GO:0071260| cellular response to mechanical stimulus IL1B;MAP3K2 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;IL1B GO:0008284| positive regulation of cell proliferation LYN;CDK2;IL1B;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IL1B GO:0032496| response to lipopolysaccharide BCR;IL1B GO:0008285| negative regulation of cell proliferation LYN;IL1B;MAP2K1 GO:0050766| positive regulation of phagocytosis IL1B;BCR GO:0043407| negative regulation of MAP kinase activity IL1B;LYN GO:0010628| positive regulation of gene expression IL1B;MAP2K1;SRC GO:0000187| activation of MAPK activity MAP3K2;IL1B;MAP2K1;MAP2K2 GO:0006915| apoptotic process IL1B;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;IL1B GO:0007165| signal transduction IL1B;MAP2K1;SRC;BCR;LYN GO:0030335| positive regulation of cell migration IL1B;LYN 4103:[DB06616 DB03864] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03864|Monothioglycerol PREP common genes common pathways 4104:[DB06616 DB09060] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLC22A8 GO:0009636| response to toxin SLC22A8;LYN GO:0006810| transport ABCC2;ABCB1 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0042493| response to drug ABCB1;SRC;ABCC2;LYN GO:0032496| response to lipopolysaccharide BCR;ABCC2 GO:0071222| cellular response to lipopolysaccharide ABCC2;ABL1;BCR;SRC 4105:[DB06616 DB04733] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways GO:0008360| regulation of cell shape ALDOA;HCK GO:0002576| platelet degranulation LYN;ALDOA 4106:[DB06616 DB00434] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0017144| drug metabolic process CYP2C8;UGT1A3;CYP3A4 GO:0007165| signal transduction HTR2C;SRC;BCR;HTR7;MAP2K1;CHRM1;CHRM2;HTR2A;LYN;HRH1;CHRM3 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K2;SRC;MAP2K1;HTR2C;ABL1 GO:0008283| cell proliferation SRC;CHRM3;CHRM1 GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1;CHRM2 GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;HTR2A;CHRM1;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;LYN;ABL1;SRC GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0016032| viral reproduction HCK;SRC;LYN;HTR2A GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0042493| response to drug HTR2C;ABCB1;SRC;HTR2A;LYN 4107:[DB06616 DB08594] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08594|TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 4108:[DB06616 DB04114] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways GO:0006260| DNA replication CDK2;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0008283| cell proliferation SRC;ACHE 4109:[DB06616 DB01599] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01599|Probucol ABCA1;CES1 common genes common pathways GO:0042493| response to drug ABCB1;SRC;LYN;ABCA1 GO:0006629| lipid metabolic process CYP3A4;ABCA1 GO:0071222| cellular response to lipopolysaccharide ABCA1;ABL1;BCR;SRC GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0071300| cellular response to retinoic acid LYN;ABCA1 GO:0055085| transmembrane transport ABCB1;ABCA1 GO:0009636| response to toxin CES1;LYN GO:0032489| regulation of Cdc42 protein signal transduction ABL1;ABCA1 GO:0045332| phospholipid translocation ABCA1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;ABCA1;CYP2C8 4110:[DB06616 DB04559] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04559|N-(Chlorophenyl)-N'-Hydroxyguanidine NOS3 common genes common pathways GO:0043542| endothelial cell migration NOS3;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS3 GO:0008285| negative regulation of cell proliferation MAP2K1;NOS3;LYN 4111:[DB06616 DB02485] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 4112:[DB06616 DB08153] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08153|(5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE HSP90AB1 common genes common pathways GO:0010033| response to organic substance HSP90AB1;CDK2 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;HSP90AB1 GO:1900034| CAMK2G;HSP90AB1 GO:0042493| response to drug LYN;HSP90AB1;SRC;ABCB1 GO:0038096| LYN;HSP90AB1;ABL1;HCK;SRC GO:0045597| positive regulation of cell differentiation HSP90AB1;MAP2K1 GO:0043066| negative regulation of apoptotic process HSP90AB1;HCK;SRC GO:0006805| xenobiotic metabolic process CYP3A4;HSP90AB1;CYP2C8 4113:[DB06616 DB04250] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04250|Butyrylthiocholine BCHE;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0042493| response to drug SRC;ABCB1;BCHE;LYN 4114:[DB06616 DB05936] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05936|CVT-6883 ADORA2B common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;ADORA2B;LYN GO:0031668| cellular response to extracellular stimulus LYN;ADORA2B GO:0000187| activation of MAPK activity MAP3K2;ADORA2B;MAP2K1;MAP2K2 4115:[DB06616 DB08426] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08426|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation LYN;F10 4116:[DB06616 DB03305] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03305|N5-Iminoethyl-L-Ornithine NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;NOS3;HCK GO:0043542| endothelial cell migration NOS3;ABL1 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0008285| negative regulation of cell proliferation MAP2K1;NOS3;LYN 4117:[DB06616 DB01736] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01736|[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium SLC25A4 common genes common pathways GO:0006810| transport ABCB1;SLC25A4 GO:0055085| transmembrane transport SLC25A4;ABCB1 GO:0016032| viral reproduction SLC25A4;LYN;HCK;SRC 4118:[DB06616 DB03604] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03604|Tiratricol THRB common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent THRB;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;THRB 4119:[DB06616 DB00132] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00132|Alpha-Linolenic Acid FADS1;FADS2;SLC8A1;TRPV1;ELOVL4;PPARA;NR1H4;PPARD;PPARG;RXRA;FABP7 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;PPARD;PPARA;PPARG;RXRA;CDK2 GO:0042493| response to drug PPARG;LYN;ABCB1;SLC8A1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;FADS1;RXRA;PPARA;PPARG;PPARD;NR1H4 GO:0055114| oxidation-reduction process FADS1;CYP3A4;CYP2C8;FADS2 GO:0006816| calcium ion transport TRPV1;SLC8A1;CAMK2G GO:0016032| viral reproduction HCK;SRC;LYN;RXRA GO:0006954| inflammatory response TRPV1;HCK;LYN;NR1H4 GO:0050728| negative regulation of inflammatory response PPARA;NR1H4;PPARD;BCR GO:0046628| positive regulation of insulin receptor signaling pathway SRC;NR1H4 GO:0051924| regulation of calcium ion transport CAMK2G;SLC8A1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;NR1H4 GO:0042127| regulation of cell proliferation ABL1;SRC;PPARD GO:0071398| cellular response to fatty acid SRC;NR1H4 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043066| negative regulation of apoptotic process PPARD;NR1H4;HCK;SRC GO:0043065| positive regulation of apoptotic process SRC;TRPV1;ABL1;PPARG GO:0008284| positive regulation of cell proliferation HCK;PPARD;CDK2;LYN GO:0042542| response to hydrogen peroxide SRC;SLC8A1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;NR1H4;PPARD GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process FADS1;PPARG;CYP3A4;PPARA;PPARD;ELOVL4;TRPV1;FADS2 GO:0045087| innate immune response LYN;PPARG;NR1H4;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;PPARD;NR1H4;CDK2;RXRA;PPARG;PPARA GO:0007507| heart development PPARD;RXRA;PPARA;PPARG;MAP2K1 GO:0007399| nervous system development FABP7;CAMK2G GO:0014070| response to organic cyclic compound LYN;PPARG GO:0008283| cell proliferation SRC;PPARD GO:0006915| apoptotic process ABL1;PPARD GO:0032868| response to insulin stimulus LYN;PPARA GO:0055085| transmembrane transport ABCB1;SLC8A1;TRPV1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;PPARD GO:0034614| cellular response to reactive oxygen species SRC;SLC8A1 GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN;FABP7 GO:0010033| response to organic substance PPARD;PPARG;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARD;PPARG GO:0034605| cellular response to heat TRPV1;LYN GO:0043434| response to peptide hormone stimulus TRPV1;LYN GO:0006810| transport TRPV1;ABCB1 GO:0030154| cell differentiation HCK;PPARD;CAMK2G GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0007204| elevation of cytosolic calcium ion concentration SLC8A1;TRPV1;ABL1 GO:0071456| cellular response to hypoxia PPARD;SRC;SLC8A1 GO:0002376| immune system process NR1H4;LYN;HCK;SRC GO:0065009| regulation of molecular function TRPV1;CAMK2G GO:0007165| signal transduction MAP2K1;SRC;BCR;NR1H4;LYN;PPARG 4120:[DB06616 DB11755] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0006816| calcium ion transport TRPA1;CAMK2G;TRPV2;TRPM8 GO:0010976| positive regulation of neuron projection development LYN;CNR1 GO:0050728| negative regulation of inflammatory response BCR;CNR2 GO:0006954| inflammatory response HCK;CNR2;LYN GO:0042493| response to drug SRC;ABCB1;TRPA1;LYN GO:0043065| positive regulation of apoptotic process CNR1;SRC;ABL1 GO:0042542| response to hydrogen peroxide TRPA1;SRC GO:0008284| positive regulation of cell proliferation HTR1A;CDK2;LYN;HCK GO:0032496| response to lipopolysaccharide BCR;CNR1;CNR2 GO:0010033| response to organic substance TRPA1;CDK2 GO:0055085| transmembrane transport TRPV2;ABCB1;TRPM8;TRPA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;ABL1;MAP2K2;SRC;MAP2K1 GO:0014070| response to organic cyclic compound LYN;TRPA1 GO:0008283| cell proliferation SRC;HTR1A GO:0007165| signal transduction SRC;BCR;MAP2K1;HTR1A;GPR55;CNR1;LYN;CNR2 GO:0045453| bone resorption SRC;GPR55 GO:0006810| transport TRPV2;ABCB1 4121:[DB06616 DB03129] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03129|[3-(1,3,2-Dioxaborolan-2-Yloxy)Propyl]Guanidine PRSS3 common genes common pathways GO:0043542| endothelial cell migration ABL1;PRSS3 4122:[DB06616 DB04672] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways GO:0006260| DNA replication CDK2;NT5M 4123:[DB06616 DB06140] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06140|SUVN-502 HTR6 common genes common pathways GO:0007165| signal transduction LYN;HTR6;BCR;SRC;MAP2K1 4124:[DB06616 DB00702] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00702|Icodextrin AMY2A common genes common pathways 4125:[DB06616 DB01425] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01425|Alizapride DRD2 common genes common pathways GO:0042493| response to drug LYN;DRD2;SRC;ABCB1 GO:0035556| intracellular signal transduction BCR;SRC;DRD2;CAMK2G;LYN GO:0048678| response to axon injury LYN;DRD2 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;DRD2;SRC;MAP2K2 GO:0009636| response to toxin LYN;DRD2 GO:0007165| signal transduction SRC;DRD2;BCR;MAP2K1;LYN GO:0030900| forebrain development DRD2;SRC 4126:[DB06616 DB01057] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01057|Echothiophate BCHE;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0042493| response to drug BCHE;LYN;SRC;ABCB1 GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation ALB;LYN 4127:[DB06616 DB01998] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways GO:0002576| platelet degranulation SERPINA1;LYN GO:0007596| blood coagulation SERPINA1;LYN 4128:[DB06616 DB13168] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response ALOX5;HCK;PTGS2;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS2;FADS1;CYP3A4;FADS2;ALOX5;CYP2C8 GO:0042493| response to drug LYN;PTGS2;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;FADS1 GO:0006629| lipid metabolic process FADS2;PTGS2;FADS1;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0042127| regulation of cell proliferation SRC;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0034605| cellular response to heat LYN;PTGS2 4129:[DB06616 DB03066] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0050900| leukocyte migration SRC;SLC16A1;LYN;SLC16A3 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0055085| transmembrane transport ABCB1;SLC16A1;SLC16A7;SLC16A3 4130:[DB06616 DB11892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug LYN;CYP1A2;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 4131:[DB06616 DB06756] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;BCL2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis BCL2;ABL1 GO:0008283| cell proliferation SRC;BCL2 GO:0006470| protein dephosphorylation CAMK2G;BCL2 GO:0009636| response to toxin LYN;BCL2 GO:0042100| B cell proliferation BCL2;ABL1 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0018107| peptidyl-threonine phosphorylation BCL2;CAMK2G;MAP2K1 GO:0006915| apoptotic process ABL1;BCL2 GO:0009791| post-embryonic development BCL2;ABL1 GO:0030336| negative regulation of cell migration BCL2;BCR GO:0050853| B cell receptor signaling pathway ABL1;BCL2;LYN GO:0008285| negative regulation of cell proliferation BCHE;BCL2;LYN;MAP2K1 GO:0014911| positive regulation of smooth muscle cell migration BCL2;SRC GO:0098609| SRC;BCL2 GO:0071456| cellular response to hypoxia BCL2;SRC GO:0045930| negative regulation of mitotic cell cycle BCL2;ABL1 GO:0048536| spleen development BCL2;ABL1 GO:0048538| thymus development BCL2;ABL1;MAP2K1 GO:0006979| response to oxidative stress BCL2;ABL1 GO:0003014| renal system process BCR;BCL2 GO:0030097| hemopoiesis BCL2;LYN GO:0042493| response to drug BCL2;BCHE;LYN;SRC;ABCB1 GO:0051902| negative regulation of mitochondrial depolarization SRC;BCL2 GO:0010506| regulation of autophagy ABL1;BCL2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PRODH GO:2000811| negative regulation of anoikis SRC;BCL2 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2 GO:0051924| regulation of calcium ion transport BCL2;CAMK2G GO:0001782| B cell homeostasis LYN;BCL2 GO:0008284| positive regulation of cell proliferation BCL2;LYN;CDK2;HCK GO:0042542| response to hydrogen peroxide BCL2;SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR;BCL2 GO:0018105| peptidyl-serine phosphorylation SRC;BCL2;CAMK2G;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;BCL2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;BCL2;MAP3K2 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;BCL2 4132:[DB06616 DB07389] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NOS2 GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NOS2 4133:[DB06616 DB03073] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03073|3-Methoxybenzamide PARP1 common genes common pathways GO:1901216| PARP1;ABL1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0006281| DNA repair ABL1;CDK2;PARP1 GO:0006974| response to DNA damage stimulus PARP1;CDK2;LYN;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0006915| apoptotic process PARP1;ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:1900182| SRC;PARP1 4134:[DB06616 DB03009] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03009|2-[(2-Oxo-2-Piperidin-1-Ylethyl)Thio]-6-(Trifluoromethyl)Pyrimidin-4(1h)-One FABP4 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent FABP4;SRC GO:0050727| regulation of inflammatory response HCK;FABP4;LYN 4135:[DB06616 DB00787] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways GO:0006810| transport SLC10A2;ABCB1 GO:0055085| transmembrane transport SLC22A8;SLC22A1;SLC22A6;SLC47A2;SLC10A2;ABCB1;SLC47A1 GO:0006855| drug transmembrane transport SLC22A1;SLC47A2;ABCB1;SLC47A1 GO:0009636| response to toxin SLC22A8;LYN 4136:[DB06616 DB09332] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0007596| blood coagulation LYN;F10;PROS1;F9;VKORC1;F7;PROC;F2;GGCX GO:0014070| response to organic cyclic compound F7;LYN GO:0071375| cellular response to peptide hormone stimulus POR;SRC GO:0006464| protein modification process GGCX;ABL1 GO:0030168| platelet activation F2;SRC;LYN GO:0030335| positive regulation of cell migration F7;LYN;F10 GO:0009725| response to hormone stimulus F7;LYN GO:0017144| drug metabolic process VKORC1;CYP3A4;CYP2C8 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol F2;ABL1 GO:1900182| F2;SRC GO:0050900| leukocyte migration F2;PROC;SRC;LYN;PROS1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;F2 GO:0055114| oxidation-reduction process CYP2C8;POR;CYP3A4;VKORC1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;POR GO:0042493| response to drug LYN;POR;SRC;ABCB1 GO:0031667| response to nutrient levels SRC;F7 GO:0051897| positive regulation of protein kinase B signaling cascade F10;F7;SRC GO:0050728| negative regulation of inflammatory response PROC;BCR GO:0007275| multicellular organismal development F2;CAMK2G;CDK2 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC;F7 GO:0008360| regulation of cell shape F2;HCK GO:0008284| positive regulation of cell proliferation CDK2;LYN;F2;HCK GO:0002576| platelet degranulation PROS1;LYN GO:0043066| negative regulation of apoptotic process HCK;PROC;SRC;POR GO:0006805| xenobiotic metabolic process CYP2C8;POR;CYP3A4 4137:[DB06616 DB01750] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01750|1-naphthaleneacetic acid SKP1 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SKP1;SRC GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1;SKP1 GO:0038095| LYN;SKP1 4138:[DB06616 DB02596] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02596|Alpha,Beta-Methyleneadenosine-5'-Triphosphate folK;panC;nadE;NMNAT3;carA common genes common pathways 4139:[DB06616 DB05327] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05327|Ranirestat AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;AKR1B1 GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 GO:0010033| response to organic substance CDK2;AKR1B1 4140:[DB06616 DB08051] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0043542| endothelial cell migration DPP4;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;DPP4;HCK GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0031295| T cell costimulation LYN;DPP4;SRC 4141:[DB06616 DB08127] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways GO:0007165| signal transduction LYN;CRABP2;SRC;BCR;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent CRABP2;ABL1 4142:[DB06616 DB03023] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes SRC;LYN common pathways GO:0050855| regulation of B cell receptor signaling pathway LYN GO:0002376| immune system process HCK;SRC;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0070304| positive regulation of stress-activated protein kinase signaling cascade LYN GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0050861| positive regulation of B cell receptor signaling pathway LYN GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0034144| negative regulation of toll-like receptor 4 signaling pathway LYN GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0009725| response to hormone stimulus LYN GO:0031648| protein destabilization SRC GO:1902533| SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0070542| response to fatty acid SRC GO:0070372| regulation of ERK1 and ERK2 cascade LYN GO:0070555| response to interleukin-1 SRC GO:0030097| hemopoiesis LYN;LCK GO:0031668| cellular response to extracellular stimulus LYN GO:0034136| negative regulation of toll-like receptor 2 signaling pathway LYN GO:0002774| Fc receptor mediated inhibitory signaling pathway LYN GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;LCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0031295| T cell costimulation LCK;SRC;LYN GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0051279| regulation of release of sequestered calcium ion into cytosol LYN GO:0060491| regulation of cell projection assembly SRC GO:0006991| response to sterol depletion LYN GO:0030335| positive regulation of cell migration LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LCK;LYN GO:0043434| response to peptide hormone stimulus LYN GO:0034605| cellular response to heat LYN GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;LCK;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0048477| oogenesis SRC GO:0030889| negative regulation of B cell proliferation LYN GO:0071456| cellular response to hypoxia SRC GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0033003| regulation of mast cell activation LYN GO:0030168| platelet activation LCK;SRC;LYN GO:0002513| tolerance induction to self antigen LYN GO:0043149| stress fiber assembly SRC GO:0050853| B cell receptor signaling pathway LCK;ABL1;LYN GO:1902961| LYN GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;SRC;BCR GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:1902532| LYN GO:0034614| cellular response to reactive oxygen species SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0007411| axon guidance SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0043407| negative regulation of MAP kinase activity LYN GO:0002431| Fc receptor mediated stimulatory signaling pathway LYN GO:0008285| negative regulation of cell proliferation MAP2K1;LYN GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0097028| dendritic cell differentiation LYN GO:0031175| neuron projection development LYN GO:0050690| regulation of defense response to virus by virus HCK;LCK GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN GO:0038095| LYN GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0045646| regulation of erythrocyte differentiation LYN GO:0007596| blood coagulation LYN GO:0043200| response to amino acid stimulus LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1 GO:0006470| protein dephosphorylation LCK;CAMK2G GO:0016477| cell migration SRC;LCK GO:0014070| response to organic cyclic compound LYN GO:0009636| response to toxin LYN GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0050663| cytokine secretion LYN GO:0045785| positive regulation of cell adhesion SRC GO:0032868| response to insulin stimulus LYN GO:0033628| regulation of cell adhesion mediated by integrin LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1 GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0050727| regulation of inflammatory response HCK;LYN GO:0043304| regulation of mast cell degranulation LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0002576| platelet degranulation LYN GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0060252| positive regulation of glial cell proliferation LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071398| cellular response to fatty acid SRC GO:0071300| cellular response to retinoic acid LYN GO:0002902| regulation of B cell apoptosis LYN GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0051272| positive regulation of cellular component movement LYN GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0042327| positive regulation of phosphorylation LYN GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0045087| innate immune response LYN;ABL1;HCK;LCK;SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0070668| positive regulation of mast cell proliferation LYN GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0006974| response to DNA damage stimulus CDK2;LYN;ABL1 GO:2000670| positive regulation of dendritic cell apoptosis LYN GO:0050777| negative regulation of immune response LYN GO:0070447| positive regulation of oligodendrocyte progenitor proliferation LYN GO:0001932| regulation of protein phosphorylation MAP2K1;LYN GO:0042127| regulation of cell proliferation SRC;LCK;ABL1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0045056| transcytosis SRC GO:0001933| negative regulation of protein phosphorylation LYN GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:0086098| SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;BCR;MAP2K2;HCK;LCK;MAP2K1;ABL1 GO:0048678| response to axon injury LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN GO:0010976| positive regulation of neuron projection development LYN GO:0090330| regulation of platelet aggregation LYN GO:0006954| inflammatory response LYN;HCK GO:0002768| immune response-regulating cell surface receptor signaling pathway LYN GO:0002553| histamine secretion by mast cell LYN GO:0050707| regulation of cytokine secretion LYN GO:0002762| negative regulation of myeloid leukocyte differentiation LYN GO:0016032| viral reproduction LCK;HCK;SRC;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0009743| response to carbohydrate stimulus LYN GO:0038096| LYN;SRC;HCK;ABL1 GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:0001782| B cell homeostasis LYN GO:0001817| regulation of cytokine production LYN GO:0071498| cellular response to fluid shear stress SRC GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0030218| erythrocyte differentiation LYN GO:0071803| positive regulation of podosome assembly SRC GO:0070667| negative regulation of mast cell proliferation LYN GO:0002250| adaptive immune response LYN GO:0038083| LYN;SRC;LCK;HCK;ABL1 GO:0042493| response to drug SRC;ABCB1;LCK;LYN GO:0014003| oligodendrocyte development LYN GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0060369| positive regulation of Fc receptor mediated stimulatory signaling pathway LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;MAP3K2;CDK2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0023014| signal transduction via phosphorylation event LYN GO:0050900| leukocyte migration SRC;LCK;LYN GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0090025| regulation of monocyte chemotaxis LYN GO:0043114| regulation of vascular permeability SRC;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0001934| positive regulation of protein phosphorylation ABL1;LYN GO:0034332| adherens junction organization SRC 4143:[DB06616 DB04930] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04930|Permethrin SCN1A;ESR1;NR1I2;CYP2B6;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction SRC;BCR;MAP2K1;ESR1;LYN;NR1I2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP2B6;NR1I2;CYP3A4;CYP2C8 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;NR1I2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1I2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0055085| transmembrane transport ABCB1;SCN1A GO:0036378| CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;NR1I2;CYP2B6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0060065| uterus development ESR1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;NR1I2;ESR1;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2B6;NR1I2;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1I2;ESR1 GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 4144:[DB06616 DB07274] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07274|N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;KDR;MAP2K1;MAP2K2;SRC GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;KDR;ABL1;CAMK2G;LYN GO:0030154| cell differentiation CAMK2G;HCK;KDR GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;KDR GO:0016310| phosphorylation ABL1;HCK;KDR;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2 GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;KDR GO:0030335| positive regulation of cell migration KDR;LYN GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0038083| ABL1;SRC;KDR;HCK;LYN GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;KDR GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0016032| viral reproduction KDR;HCK;SRC;LYN GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;HCK;KDR;MAP2K1;SRC;BCR;MAP2K2 GO:0007275| multicellular organismal development CAMK2G;CDK2;KDR GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0008360| regulation of cell shape KDR;HCK GO:0008284| positive regulation of cell proliferation HCK;KDR;CDK2;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;KDR GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC 4145:[DB06616 DB07979] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07979|(2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;CYP2C8;CYP3A4 4146:[DB06616 DB07827] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07827|4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID MMP13 common genes common pathways 4147:[DB06616 DB03344] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03344|Inositol-(1,3,4,5,6)-Pentakisphosphate CYTH3 common genes common pathways GO:0065009| regulation of molecular function CYTH3;CAMK2G GO:0045785| positive regulation of cell adhesion SRC;CYTH3 4148:[DB06616 DB05130] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05130|INCB3284 CCR2 common genes common pathways GO:0030097| hemopoiesis LYN;CCR2 GO:0007165| signal transduction MAP2K1;BCR;CCR2;SRC;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCR2 GO:0016032| viral reproduction LYN;HCK;CCR2;SRC GO:0006954| inflammatory response HCK;CCR2;LYN GO:0019221| cytokine-mediated signaling pathway CCR2;HCK GO:0006935| chemotaxis CCR2;MAP2K1 4149:[DB06616 DB07060] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07060|3-(INDOL-3-YL) LACTATE HAO1 common genes common pathways GO:0006979| response to oxidative stress ABL1;HAO1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HAO1 4150:[DB06616 DB08834] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways GO:0009636| response to toxin SLC7A11;LYN GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0006979| response to oxidative stress ABL1;SLC7A11 GO:0007420| brain development SLC7A11;BCR GO:0050900| leukocyte migration SRC;SLC7A11;LYN 4151:[DB06616 DB07843] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07843|5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration F10;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 4152:[DB06616 DB03153] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 4153:[DB06616 DB12651] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12651|Bardoxolone CASP8 common genes common pathways GO:1901216| CASP8;ABL1 GO:0016032| viral reproduction LYN;HCK;SRC;CASP8 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CASP8 GO:0032496| response to lipopolysaccharide CASP8;BCR GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CASP8 GO:0071260| cellular response to mechanical stimulus MAP3K2;CASP8 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;CASP8;MAP3K2 GO:0006915| apoptotic process ABL1;CASP8 4154:[DB06616 DB00298] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00298|Dapiprazole ADRA1A;ADRA1D;ADRA1B common genes common pathways GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction ADRA1B;ADRA1A;SRC;BCR;MAP2K1;LYN;ADRA1D GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A;ADRA1D GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;ADRA1A;MAP2K2;ABL1 GO:0008283| cell proliferation SRC;ADRA1B;ADRA1D GO:0035556| intracellular signal transduction ADRA1A;SRC;BCR;ADRA1B;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation HCK;ADRA1D;CDK2;LYN GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CAMK2G;CDK2 GO:0042493| response to drug LYN;ADRA1A;SRC;ABCB1 4155:[DB06616 DB00698] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;POR GO:0043066| negative regulation of apoptotic process HCK;SRC;POR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;POR GO:0055114| oxidation-reduction process CYP3A4;POR;CYP2C8 GO:0042493| response to drug LYN;POR;ABCB1;SRC;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCB11;ABCB1;ABCG2 GO:0071375| cellular response to peptide hormone stimulus POR;SRC GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1;ABCB11 4156:[DB06616 DB00145] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;BAAT GO:0007399| nervous system development CAMK2G;GSS;GLRB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;GLYAT GO:0043065| positive regulation of apoptotic process GRIN2A;ABL1;SRC GO:0008284| positive regulation of cell proliferation HCK;SHMT2;LYN;CDK2 GO:0007275| multicellular organismal development CAMK2G;CDK2;GATM GO:0000165| MAPKKK cascade CAMK2G;GRIN2C;GRIN2A;MAP2K2;MAP2K1 GO:0030218| erythrocyte differentiation LYN;ALAS2 GO:0051924| regulation of calcium ion transport GRIN3B;CAMK2G GO:0006816| calcium ion transport GRIN2A;CAMK2G GO:0055114| oxidation-reduction process CYP3A4;GLDC;CYP2C8;PIPOX GO:0050885| neuromuscular process controlling balance GRIN2C;ABL1;BCR GO:0031667| response to nutrient levels SRC;GSS GO:0042493| response to drug SRC;ABCB1;GRIN2A;LYN GO:0065009| regulation of molecular function CAMK2G;GRIN2C;GRIN2A GO:0007165| signal transduction LYN;GPR18;MAP2K1;SRC;BCR GO:0006979| response to oxidative stress GSS;ABL1 GO:0006810| transport GRIN2C;SLC6A5;SLC6A9;GRIN2A;ABCB1 GO:0006464| protein modification process ABL1;GNMT GO:0055085| transmembrane transport SLC6A5;SLC6A9;SLC36A1;ABCB1;SLC16A10 GO:0043200| response to amino acid stimulus GSS;GLRB;LYN;GLRA3 GO:0009636| response to toxin LYN;GLYAT 4157:[DB06616 DB08892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways GO:0050900| leukocyte migration SRC;SLC16A1;LYN GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0055085| transmembrane transport ABCB1;SLC16A1 GO:0007165| signal transduction LYN;GABBR1;GABBR2;SRC;BCR;MAP2K1 4158:[DB06616 DB04410] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways GO:0045785| positive regulation of cell adhesion SRC;PRSS2 4159:[DB06616 DB00830] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3 GO:0006810| transport ABCB1;SLC6A2 GO:0042493| response to drug LYN;SLC6A2;SLC6A3;ABCB1;SRC 4160:[DB06616 DB14017] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14017|H3B-8800 SF3B1 common genes common pathways 4161:[DB06616 DB06346] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06346|Fiboflapon ALOX5AP common genes common pathways 4162:[DB06616 DB03918] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03918|6S-5,6,7,8-Tetrahydrobiopterin NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;NOS3 GO:0043542| endothelial cell migration ABL1;NOS3 GO:0008285| negative regulation of cell proliferation MAP2K1;NOS3;LYN 4163:[DB06616 DB00052] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00052|Somatotropin GHR;PRLR common genes common pathways GO:0000187| activation of MAPK activity GHR;MAP2K2;MAP2K1;MAP3K2 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;PRLR;GHR GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein GHR;LYN GO:0030155| regulation of cell adhesion ABL1;PRLR GO:0043066| negative regulation of apoptotic process PRLR;HCK;SRC GO:0006897| endocytosis GHR;ABL1 GO:0019221| cytokine-mediated signaling pathway HCK;GHR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation GHR;ABL1;SRC;LYN 4164:[DB06616 DB05967] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05967|ANZ-100 KISS1R common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;KISS1R 4165:[DB06616 DB12243] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 4166:[DB06616 DB05448] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05448|PX-12 TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process TXNRD1;CYP2C8;CYP3A4 GO:0034599| cellular response to oxidative stress TXNRD1;ABL1 GO:0008283| cell proliferation TXNRD1;SRC GO:0007165| signal transduction SRC;BCR;TXNRD1;MAP2K1;LYN 4167:[DB06616 DB11421] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11421|Imidacloprid CHRFAM7A common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CHRFAM7A 4168:[DB06616 DB07151] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07151|4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one PIM1 common genes common pathways GO:0007275| multicellular organismal development PIM1;CAMK2G;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;PIM1 GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2;PIM1 GO:0006468| protein phosphorylation MAP3K2;PIM1;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;PIM1;MAP3K2 GO:0006915| apoptotic process PIM1;ABL1 GO:0008283| cell proliferation PIM1;SRC GO:0007049| cell cycle SRC;CDK2;PIM1 GO:0046777| protein autophosphorylation ABL1;HCK;SRC;BCR;LYN;CAMK2G;PIM1 4169:[DB06616 DB04282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04282|2-deoxy-2-fluoro-α-D-glucose LCT common genes common pathways 4170:[DB06616 DB11830] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;HDAC1;HDAC2;HDAC3 GO:0008284| positive regulation of cell proliferation HDAC1;CDK2;LYN;HCK;HDAC2 GO:1901796| CDK2;HDAC1;HDAC2 GO:0043066| negative regulation of apoptotic process HDAC1;HDAC2;HDAC3;SRC;HCK GO:0071560| cellular response to transforming growth factor beta stimulus HDAC2;SRC GO:0071300| cellular response to retinoic acid HDAC2;LYN GO:0034599| cellular response to oxidative stress HDAC1;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein HDAC1;LYN;HDAC2 GO:0032496| response to lipopolysaccharide HDAC1;BCR;HDAC2 GO:0071498| cellular response to fluid shear stress HDAC3;SRC GO:0016032| viral reproduction LYN;HDAC1;HCK;SRC GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;HDAC3 GO:0006355| regulation of transcription, DNA-dependent HDAC2;ABL1;HDAC3;HDAC1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;HDAC1 GO:0042493| response to drug SRC;ABCB1;HDAC2;HDAC1;LYN GO:0045893| positive regulation of transcription, DNA-dependent HDAC1;CDK2;MAP3K2;HDAC2;SRC;MAP2K2;MAP2K1 GO:1903351| HDAC2;ABL1 GO:0034605| cellular response to heat HDAC2;LYN GO:0070301| cellular response to hydrogen peroxide ABL1;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;HDAC2;HDAC3;HDAC1 GO:0008285| negative regulation of cell proliferation HDAC1;LYN;MAP2K1 GO:0007596| blood coagulation HDAC1;LYN;HDAC2 4171:[DB06616 DB02080] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02080|1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene PLA2G2A;lepB;TTPA common genes common pathways GO:0006810| transport ABCB1;TTPA GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;PLA2G2A GO:0009636| response to toxin TTPA;LYN GO:0006629| lipid metabolic process CYP3A4;TTPA;PLA2G2A 4172:[DB06616 DB03298] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03298|Phenylphosphate SRC common genes SRC common pathways GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0042493| response to drug ABCB1;SRC;LYN GO:0038083| ABL1;SRC;HCK;LYN GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0050900| leukocyte migration LYN;SRC GO:0034332| adherens junction organization SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0016032| viral reproduction LYN;HCK;SRC GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0038096| LYN;SRC;HCK;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071498| cellular response to fluid shear stress SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0045056| transcytosis SRC GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;LYN GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G GO:0071398| cellular response to fatty acid SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0007155| cell adhesion ABL1;HCK;SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;BCR;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0036035| osteoclast development SRC GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0002376| immune system process LYN;SRC;HCK GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC 4173:[DB06616 DB05532] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05532|BMS-488043 FFAR4 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;FFAR4 GO:0007165| signal transduction LYN;FFAR4;SRC;BCR;MAP2K1 GO:0050728| negative regulation of inflammatory response BCR;FFAR4 GO:0043066| negative regulation of apoptotic process FFAR4;HCK;SRC 4174:[DB06616 DB05449] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05449|FM-VP4 ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug LYN;SRC;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 4175:[DB06616 DB07180] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;NEK2;CAMK2G;LYN GO:0007049| cell cycle SRC;CDK2;NEK2 GO:0000086| G2/M transition of mitotic cell cycle CDK2;NEK2;ABCB1 GO:0051321| meiotic cell cycle CDK2;NEK2 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;NEK2;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0006468| protein phosphorylation NEK2;MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0051301| cell division NEK2;CDK2 GO:0010389| regulation of G2/M transition of mitotic cell cycle NEK2;CDK2 GO:0000278| mitotic cell cycle NEK2;ABL1 4176:[DB06616 DB09348] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09348|Propiolactone ALB common genes common pathways GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB 4177:[DB06616 DB14001] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14001|alpha-Tocopherol succinate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HMOX1;HCK GO:0051321| meiotic cell cycle PPP2CA;CDK2 GO:0070555| response to interleukin-1 SRC;GCLC;PRKCA GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0007165| signal transduction MAP2K1;BCR;SRC;PRKCB;LYN;NR1I2 GO:0009725| response to hormone stimulus GCLC;LYN GO:0006979| response to oxidative stress SOD1;HMOX1;NQO1;GCLC;ABL1 GO:0050861| positive regulation of B cell receptor signaling pathway LYN;PRKCB GO:0002376| immune system process LYN;SRC;PRKCB;HCK GO:0048538| thymus development MAP2K1;ABL1;SOD1 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0030168| platelet activation SRC;PRKCB;PRKCA;DGKA;LYN GO:0006810| transport ABCB1;TTPA GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;PRKCB;MAP2K1;HCK;PRKCA;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0032869| cellular response to insulin stimulus SRC;GSTP1;GCLC GO:0071456| cellular response to hypoxia SRC;HMOX1 GO:0030335| positive regulation of cell migration LYN;PRKCA GO:0034605| cellular response to heat LYN;HMOX1 GO:0008202| steroid metabolic process CYP3A4;NR1I2;CYP2C8 GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0010595| positive regulation of endothelial cell migration PRKCA;ABL1 GO:0016310| phosphorylation MAP3K2;DGKA;CAMK2G;CDK2;LYN;MAP2K2;BCR;PRKCB;SRC;MAP2K1;HCK;PRKCA;ABL1 GO:0010033| response to organic substance PPP2CA;CDK2;SOD1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;HMOX1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;GCLC;NR1I2 GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1 GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0007411| axon guidance SRC;PRKCA GO:0010628| positive regulation of gene expression MAP2K1;SRC;NR1I2 GO:0050853| B cell receptor signaling pathway LYN;PRKCB;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;PPP2CA GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;SOD1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;GSTP1;MAP2K2 GO:0006915| apoptotic process PRKCB;PPP2CA;ABL1;PRKCA;HMOX1 GO:0045785| positive regulation of cell adhesion SRC;PRKCA GO:0070374| positive regulation of ERK1 and ERK2 cascade PRKCA;ABL1;MAP2K2;SRC;MAP2K1 GO:0006470| protein dephosphorylation PPP2CB;CAMK2G;PPP2CA GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1;GSTP1 GO:0009636| response to toxin LYN;TTPA;NQO1;GSTP1 GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis HMOX1;ABL1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GCLC;SRC;GSTP1 GO:0006629| lipid metabolic process TTPA;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;GCLC GO:0007155| cell adhesion SRC;HCK;PRKCA;ABL1 GO:0035556| intracellular signal transduction HMOX1;CAMK2G;LYN;DGKA;PRKCA;BCR;SRC;PRKCB GO:0006805| xenobiotic metabolic process NR1I2;NQO1;CYP3A4;CYP2C8;GSTP1 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK;GCLC;NQO1;SOD1 GO:0030155| regulation of cell adhesion ABL1;PPP2CA GO:0043065| positive regulation of apoptotic process SOD1;HMOX1;ABL1;SRC GO:0002576| platelet degranulation SOD1;LYN GO:1904528| PPP2CB;PPP2CA;ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;GSTP1;BCR;SRC GO:0042542| response to hydrogen peroxide SRC;HMOX1;PPP2CB;SOD1 GO:0018105| peptidyl-serine phosphorylation PRKCA;SRC;PRKCB;CAMK2G;CDK2 GO:0007498| mesoderm development PPP2CA;HCK GO:0048678| response to axon injury SOD1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PRKCB;ABL1;HMOX1 GO:0034599| cellular response to oxidative stress ABL1;GSTP1;SOD1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0045931| positive regulation of mitotic cell cycle ABL1;PRKCA GO:0002250| adaptive immune response PRKCB;LYN GO:0038128| PRKCA;SRC GO:0051602| response to electrical stimulus SRC;NQO1 GO:0006816| calcium ion transport CAMK2G;PRKCB GO:0090330| regulation of platelet aggregation LYN;PRKCA GO:0006954| inflammatory response HCK;ALOX5;LYN GO:0055114| oxidation-reduction process CYP2C8;ALOX5;CYP3A4;GSTO1;HMOX1;NQO1;SOD1 GO:0031667| response to nutrient levels SOD1;SRC;GSTP1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;SEC14L2;MAP3K2;CDK2;NR1I2 GO:0042493| response to drug ABCB1;SRC;SOD1;LYN GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent NR1I2;ABL1;SEC14L2;PRKCB;PPP2CA 4178:[DB06616 DB04988] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04988|IGN311 EGFR;ERBB2 common genes common pathways GO:0038128| ERBB2;EGFR;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;EGFR;ERBB2 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;EGFR;ERBB2;CAMK2G GO:0006355| regulation of transcription, DNA-dependent ERBB2;ABL1 GO:0038083| LYN;EGFR;HCK;SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;MAP2K2;EGFR;MAP2K1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;EGFR;SRC GO:0001934| positive regulation of protein phosphorylation LYN;ERBB2;ABL1;EGFR GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;EGFR GO:0043066| negative regulation of apoptotic process EGFR;HCK;SRC GO:0042327| positive regulation of phosphorylation LYN;EGFR GO:0035556| intracellular signal transduction SRC;BCR;EGFR;CAMK2G;LYN GO:2000145| regulation of cell motility ABL1;ERBB2;EGFR GO:0007399| nervous system development ERBB2;CAMK2G GO:0007507| heart development ERBB2;MAP2K1 GO:0071260| cellular response to mechanical stimulus EGFR;MAP3K2 GO:0042127| regulation of cell proliferation EGFR;SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;EGFR;MAP2K2;BCR;SRC;ERBB2;ABL1;LYN GO:0007275| multicellular organismal development EGFR;CAMK2G;CDK2 GO:0046777| protein autophosphorylation LYN;CAMK2G;EGFR;HCK;SRC;BCR;ABL1;ERBB2 GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0010628| positive regulation of gene expression SRC;MAP2K1;ERBB2 GO:0043406| positive regulation of MAP kinase activity SRC;EGFR;ERBB2 GO:0008283| cell proliferation ERBB2;SRC;EGFR GO:0014070| response to organic cyclic compound EGFR;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;EGFR;MAP2K2;SRC;ABL1 GO:0045785| positive regulation of cell adhesion ERBB2;SRC GO:0006979| response to oxidative stress EGFR;ABL1 GO:0007165| signal transduction ERBB2;BCR;SRC;MAP2K1;EGFR;LYN GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;ERBB2;LYN GO:0016310| phosphorylation ABL1;ERBB2;SRC;MAP2K2;BCR;HCK;EGFR;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;EGFR;HCK;ERBB2 GO:0043547| positive regulation of GTPase activity ERBB2;BCR GO:0098609| SRC;EGFR GO:0030335| positive regulation of cell migration LYN;EGFR GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;EGFR;ERBB2;ABL1 GO:1903800| MAP2K2;MAP2K1;EGFR GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR 4179:[DB06616 DB08058] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways GO:0006281| DNA repair PARP3;CDK2;ABL1 4180:[DB06616 DB01760] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01760|2-Methoxy-3-Isopropylpyrazine LCN9 common genes common pathways 4181:[DB06616 DB07739] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07739|(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE PNMT common genes common pathways 4182:[DB06616 DB09539] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;SOAT1;CYP2C8 GO:0006629| lipid metabolic process SOAT1;CYP3A4 4183:[DB06616 DB03953] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03953|L-Thiocitrulline NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;NOS2 4184:[DB06616 DB02933] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 4185:[DB06616 DB02056] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;AKR1C3;CYP2C8 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;SRC GO:0006935| chemotaxis MAP2K1;PTGDR2 GO:0008284| positive regulation of cell proliferation AKR1C3;LYN;CDK2;HCK GO:0055085| transmembrane transport SLCO2A1;ABCB1 GO:0030216| keratinocyte differentiation MAP2K1;AKR1C3 GO:0034614| cellular response to reactive oxygen species SRC;AKR1C3 GO:0008202| steroid metabolic process AKR1C3;CYP3A4;CYP2C8 GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;PTGDR2 4186:[DB06616 DB01294] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways GO:0002576| platelet degranulation TF;LYN;ALB GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB 4187:[DB06616 DB04723] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways 4188:[DB06616 DB04821] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0006979| response to oxidative stress MPO;ABL1 GO:0007420| brain development SLC6A4;BCR GO:0009636| response to toxin SLC6A4;MAOB;LYN;SLC18A2 GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0055085| transmembrane transport SLC18A2;SLC6A2;SLC6A3;SLC6A4;ABCB1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;SLC6A4 GO:0009791| post-embryonic development SLC18A2;ABL1 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0032496| response to lipopolysaccharide MAOB;BCR;MPO GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0043066| negative regulation of apoptotic process HCK;MPO;SRC GO:0009612| response to mechanical stimulus SRC;MPO GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0002576| platelet degranulation LYN;ORM1 GO:0042493| response to drug LYN;MAOB;SLC6A2;SLC6A4;SLC6A3;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;MPO;CYP3A4;MAOB;MAOA GO:0006954| inflammatory response HCK;ORM1;LYN 4189:[DB06616 DB04653] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04653|CBZ-LEU-LEU-TYR-CH2F CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPN1;LYN;CDK2;HCK 4190:[DB06616 DB02565] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways GO:0010629| negative regulation of gene expression HDAC8;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent HDAC8;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;HDAC8 4191:[DB06616 DB01022] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways GO:0007596| blood coagulation GGCX;LYN GO:0006464| protein modification process ABL1;GGCX 4192:[DB06616 DB03166] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0050900| leukocyte migration SRC;SLC16A1;LYN GO:0055085| transmembrane transport SLCO2B1;SLC16A1;ABCB1 4193:[DB06616 DB01075] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01075|Diphenhydramine HRH1;CHRM2;CYP2D6;CYP2C9;CYP2C19;CYP2C18;PTGS1;SLC22A2;SLC22A5 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0043114| regulation of vascular permeability HRH1;SRC;BCR GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS1;CYP2C18;CYP2C19;CYP2C8;CYP2D6 GO:0006954| inflammatory response LYN;HRH1;PTGS1;HCK GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2C19;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0009615| response to virus CHRM2;SRC GO:0006805| xenobiotic metabolic process CYP2C18;CYP2C19;CYP2C8;CYP2D6;PTGS1;CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C18;CYP2C9 GO:0007399| nervous system development CAMK2G;CHRM2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS1;CYP2D6 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A5 GO:0055085| transmembrane transport ABCB1;SLC22A2;SLC22A5 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8;CYP2D6 GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0007165| signal transduction MAP2K1;SRC;BCR;CHRM2;LYN;HRH1 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0097267| CYP2C19;CYP2C8;CYP2C9 4194:[DB06616 DB07616] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways GO:0007165| signal transduction BCR;HPGDS;SRC;MAP2K1;LYN GO:0006629| lipid metabolic process HPGDS;CYP3A4 4195:[DB06616 DB07136] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 4196:[DB06616 DB04576] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2;TOP2A GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0043065| positive regulation of apoptotic process ABL1;SRC;TOP2A GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 4197:[DB06616 DB02337] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 4198:[DB06616 DB14641] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes ABCB1 common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0007165| signal transduction MAP2K1;SRC;BCR;ESR2;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0042493| response to drug SRC;ABCB1;LYN GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;MAP2K2;SRC;MAP2K1;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;ESR2 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2;ESR1 GO:0060065| uterus development SRC;ESR1 GO:1901529| ABCB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 4199:[DB06616 DB00116] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0070555| response to interleukin-1 SRC;MTHFR GO:0001843| neural tube closure MTHFD1;ABL1 GO:0006810| transport ABCC2;ABCB1 GO:0043200| response to amino acid stimulus LYN;MTHFR GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0071732| cellular response to nitric oxide MTR;CDK2 GO:0008284| positive regulation of cell proliferation HCK;SHMT2;LYN;CDK2 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;ABCC2 GO:0007507| heart development MTHFD1;MAP2K1 GO:0007399| nervous system development CAMK2G;MTR GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:0048678| response to axon injury LYN;MTR GO:0042493| response to drug LYN;MTHFR;ABCC2;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;ALDH1L1;MTHFD1;MTHFD2;MTHFR;CYP2C8 4200:[DB06616 DB02158] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 4201:[DB06616 DB05033] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05033|INCB7839 ADAM9 common genes common pathways GO:0042542| response to hydrogen peroxide SRC;ADAM9 GO:0071222| cellular response to lipopolysaccharide ADAM9;ABL1;SRC;BCR GO:0007155| cell adhesion ADAM9;ABL1;HCK;SRC GO:0030216| keratinocyte differentiation ADAM9;MAP2K1 GO:0016477| cell migration ADAM9;SRC GO:0007179| transforming growth factor beta receptor signaling pathway ADAM9;SRC GO:0007229| integrin-mediated signaling pathway ABL1;ADAM9;SRC;HCK GO:0000186| activation of MAPKK activity MAP3K2;ADAM9 4202:[DB06616 DB13998] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:1900026| CALR;ABL1 GO:0032956| regulation of actin cytoskeleton organization LRP1;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;F2 GO:1900182| SRC;F2 GO:0051222| positive regulation of protein transport SRC;LRP1 GO:0030335| positive regulation of cell migration HSPA5;F10;LYN GO:0010595| positive regulation of endothelial cell migration CALR;ABL1 GO:0030168| platelet activation VWF;LYN;SRC;F2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;CALR GO:0045892| negative regulation of transcription, DNA-dependent SRC;CALR GO:0050766| positive regulation of phagocytosis CALR;BCR GO:0010033| response to organic substance CDK2;CALR GO:0030182| neuron differentiation ABL1;MAP2K1;HSPA5 GO:0008283| cell proliferation SRC;LRP1 GO:0007596| blood coagulation VWF;LYN;F10;F9;PROC;LMAN1;F2 GO:0043066| negative regulation of apoptotic process PROC;HCK;SRC;HSPA5 GO:0006897| endocytosis LRP1;ASGR2;ABL1 GO:0008284| positive regulation of cell proliferation CALR;LYN;CDK2;F2;HCK GO:0002576| platelet degranulation LYN;VWF GO:0006629| lipid metabolic process CYP3A4;LRP1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;CALR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CALR GO:0007155| cell adhesion VWF;SRC;HCK;ABL1 GO:0008360| regulation of cell shape F2;HCK GO:0045056| transcytosis SRC;LRP1 GO:0007275| multicellular organismal development LRP1;CDK2;CAMK2G;F2 GO:0090398| cellular senescence CALR;MAP2K1 GO:0050728| negative regulation of inflammatory response BCR;PROC GO:0010976| positive regulation of neuron projection development HSPA5;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0006909| phagocytosis LRP1;HCK;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CALR GO:0042493| response to drug SRC;ABCB1;CALR;LYN GO:0001934| positive regulation of protein phosphorylation LYN;F2;ABL1 GO:0055114| oxidation-reduction process CYP2C8;PHYH;CYP3A4 GO:0050900| leukocyte migration F2;PROC;SRC;LYN 4203:[DB06616 DB08835] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC36A1 4204:[DB06616 DB05460] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05460|Ezatiostat GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;HCK;GSTP1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;GSTP1;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ABL1 GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0031667| response to nutrient levels SRC;GSTP1 GO:0014003| oligodendrocyte development GSTP1;LYN GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN GO:0007417| central nervous system development GSTP1;SRC;LYN GO:0032869| cellular response to insulin stimulus GSTP1;SRC GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:0043200| response to amino acid stimulus LYN;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0009636| response to toxin GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0032872| regulation of stress-activated MAPK cascade GSTP1;MAP2K1;MAP2K2 4205:[DB06616 DB03288] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways 4206:[DB06616 DB05299] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration IL2;ABL1 GO:0002376| immune system process IL2;HCK;SRC;LYN GO:0065009| regulation of molecular function CAMK2G;IL2 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;IL2 GO:0050728| negative regulation of inflammatory response IL2;BCR GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;IL2;CAMK2G GO:0002250| adaptive immune response IL2;LYN GO:0001933| negative regulation of protein phosphorylation IL2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL2 GO:0043066| negative regulation of apoptotic process SRC;HCK;IL2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;IL2;HCK GO:0007155| cell adhesion IL2;ABL1;HCK;SRC 4207:[DB06616 DB00611] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;OPRK1 GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;LYN;MAP2K1;SRC;BCR;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;OPRM1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;OPRM1 4208:[DB06616 DB03114] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03114|PAS219 SRC common genes SRC common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;HCK;ABL1 GO:0051895| negative regulation of focal adhesion assembly SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0007411| axon guidance SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0043406| positive regulation of MAP kinase activity SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle CDK2;SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1 GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0016310| phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0031295| T cell costimulation LYN;SRC GO:0036120| SRC GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0098609| SRC GO:0071456| cellular response to hypoxia SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MAP3K2 GO:0048477| oogenesis SRC GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction SRC;HCK;LYN GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0031954| positive regulation of protein autophosphorylation SRC GO:0038128| SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038096| ABL1;HCK;SRC;LYN GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0038083| SRC;HCK;ABL1;LYN GO:0042493| response to drug SRC;ABCB1;LYN GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;MAP2K2;SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0050900| leukocyte migration SRC;LYN GO:0034332| adherens junction organization SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0060065| uterus development SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction SRC;BCR;CAMK2G;LYN GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0045087| innate immune response LYN;ABL1;HCK;SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0045056| transcytosis SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0086098| SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 4209:[DB06616 DB02105] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0014070| response to organic cyclic compound LYN;COMT GO:0042493| response to drug SRC;ABCB1;COMT;LYN GO:0032496| response to lipopolysaccharide BCR;COMT 4210:[DB06616 DB09072] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways GO:0007417| central nervous system development ALDH5A1;SRC;LYN GO:0009791| post-embryonic development ALDH5A1;ABL1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;ADHFE1;ALDH5A1 4211:[DB06616 DB03203] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes ABCB1 common pathways GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0034332| adherens junction organization SRC;PVR GO:0042493| response to drug LYN;SRC;ABCB1 GO:0016032| viral reproduction LYN;PVR;HCK;SRC GO:1901529| ABCB1 GO:0007155| cell adhesion SRC;PVR;HCK;ABL1 GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 4212:[DB06616 DB13988] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13988|SB-269970 HTR7 common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;HTR7;BCR;SRC 4213:[DB06616 DB04350] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04350|Argadin CHIT1 common genes common pathways 4214:[DB06616 DB07358] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07358|2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways GO:0032869| cellular response to insulin stimulus GCK;SRC GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;GCK;MAP3K2;CAMK2G;LYN;CDK2 4215:[DB06616 DB11726] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11726|Encenicline CHRNA7 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CHRNA7;CDK2;LYN GO:0006816| calcium ion transport CAMK2G;CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1;LYN GO:0007165| signal transduction LYN;CHRNA7;BCR;SRC;MAP2K1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;CHRNA7;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;ABL1;MAP2K1;MAP2K2;SRC 4216:[DB06616 DB02908] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02908|RU78783 SRC common genes SRC common pathways GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1 GO:2000386| positive regulation of ovarian follicle development SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation ABL1;HCK;BCR;SRC;LYN;CAMK2G GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response LYN;ABL1;SRC;HCK GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;BCR GO:0071398| cellular response to fatty acid SRC GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0045056| transcytosis SRC GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0038096| HCK;SRC;ABL1;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071498| cellular response to fluid shear stress SRC GO:0016032| viral reproduction SRC;HCK;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0050900| leukocyte migration LYN;SRC GO:0034332| adherens junction organization SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0042493| response to drug ABCB1;SRC;LYN GO:0038083| LYN;HCK;SRC;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2 4217:[DB06616 DB01055] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01055|Mimosine SHMT1;CCL2;TYR common genes common pathways GO:0007155| cell adhesion CCL2;SRC;HCK;ABL1 GO:0008360| regulation of cell shape CCL2;HCK GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;CCL2;HCK GO:0071222| cellular response to lipopolysaccharide CCL2;SRC;BCR;ABL1 GO:0006935| chemotaxis CCL2;MAP2K1 GO:0055114| oxidation-reduction process CYP3A4;TYR;CYP2C8 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CCL2;CAMK2G GO:0019221| cytokine-mediated signaling pathway CCL2;HCK GO:0006954| inflammatory response CCL2;LYN;HCK GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;CCL2;LYN;CAMK2G;MAP3K2 GO:0043547| positive regulation of GTPase activity BCR;CCL2 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;CCL2 GO:0048538| thymus development TYR;ABL1;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;CCL2 GO:0008283| cell proliferation SRC;TYR 4218:[DB06616 DB07841] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07841|Geranylgeranyl diphosphate FNTA;PGGT1B;FNTB;GGPS1;FDPS;RABGGTA;RABGGTB common genes common pathways GO:0016032| viral reproduction LYN;SRC;HCK;FDPS GO:0008284| positive regulation of cell proliferation CDK2;LYN;PGGT1B;HCK GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042981| regulation of apoptotic process RABGGTB;MAP3K2;RABGGTA;MAP2K2;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;FNTB GO:0006464| protein modification process RABGGTB;ABL1;RABGGTA GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;SRC GO:0008202| steroid metabolic process FDPS;CYP2C8;CYP3A4 4219:[DB06616 DB04657] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04657|Carboxin SDHA common genes common pathways GO:0007399| nervous system development SDHA;CAMK2G GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;SDHA 4220:[DB06616 DB00779] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;TDO2;CYP3A4 4221:[DB06616 DB01086] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes ABCB1 common pathways GO:0009636| response to toxin CES1;LYN GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport ABCB1;SCN10A GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0042493| response to drug SRC;ABCB1;LYN GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:1901529| ABCB1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 4222:[DB06616 DB00858] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0051259| protein oligomerization AR;CAMK2G GO:0060065| uterus development CYP19A1;SRC GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation HCK;AR;CDK2;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent AR;MAP2K2;SRC;MAP2K1;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0055114| oxidation-reduction process CYP2C8;CYP19A1;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0006810| transport ABCB1;AR GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation SRC;AR GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 4223:[DB06616 DB01562] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 4224:[DB06616 DB08042] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08042|N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0008360| regulation of cell shape KDR;HCK GO:0043066| negative regulation of apoptotic process HCK;KDR;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR GO:0008284| positive regulation of cell proliferation HCK;KDR;CDK2;LYN GO:0007275| multicellular organismal development CDK2;CAMK2G;KDR GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;KDR;MAP2K1;SRC;BCR;MAP2K2;LYN GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0016032| viral reproduction LYN;HCK;KDR;SRC GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;KDR;MAP2K1 GO:0038083| LYN;ABL1;SRC;HCK;KDR GO:0030154| cell differentiation HCK;KDR;CAMK2G GO:0006468| protein phosphorylation ABL1;HCK;KDR;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2 GO:0030335| positive regulation of cell migration LYN;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;KDR;LYN GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;KDR;MAP2K1;HCK;ABL1 GO:0046777| protein autophosphorylation HCK;KDR;SRC;BCR;ABL1;LYN;CAMK2G GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;KDR;SRC;MAP2K2 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR 4225:[DB06616 DB06554] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06554|Gaboxadol SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 4226:[DB06616 DB08363] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08363|1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine TP53 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;TP53 GO:0016032| viral reproduction HCK;SRC;LYN;TP53 GO:0006914| autophagy ABL1;TP53 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;TP53;CDK2 GO:0042493| response to drug TP53;LYN;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent TP53;ABL1 GO:0051974| negative regulation of telomerase activity SRC;TP53 GO:0006974| response to DNA damage stimulus CDK2;LYN;TP53;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TP53 GO:0042981| regulation of apoptotic process TP53;MAP3K2;MAP2K1;MAP2K2 GO:0031571| mitotic cell cycle G1/S transition DNA damage checkpoint TP53;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;TP53 GO:0043065| positive regulation of apoptotic process SRC;ABL1;TP53 GO:1901796| TP53;CDK2 GO:0007275| multicellular organismal development CDK2;CAMK2G;TP53 GO:0007265| Ras protein signal transduction CDK2;TP53 GO:0008285| negative regulation of cell proliferation LYN;TP53;MAP2K1 GO:0007049| cell cycle SRC;CDK2;TP53 GO:0045892| negative regulation of transcription, DNA-dependent TP53;SRC GO:0010628| positive regulation of gene expression TP53;SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species TP53;SRC GO:0006915| apoptotic process TP53;ABL1 GO:0043200| response to amino acid stimulus LYN;TP53 GO:0014070| response to organic cyclic compound LYN;TP53 GO:0008283| cell proliferation TP53;SRC GO:0007050| cell cycle arrest TP53;MAP2K1;ABL1 GO:0006979| response to oxidative stress TP53;ABL1 GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;TP53 GO:0030154| cell differentiation CAMK2G;TP53;HCK GO:0071456| cellular response to hypoxia SRC;TP53 GO:0034605| cellular response to heat LYN;TP53 4227:[DB06616 DB02853] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02853|D-Proline SLC36A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC36A1 4228:[DB06616 DB04275] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04275|N-acetylserotonin SPR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;SPR 4229:[DB06616 DB00016] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00016|Erythropoietin EPOR common genes common pathways GO:0019221| cytokine-mediated signaling pathway EPOR;HCK GO:0007507| heart development MAP2K1;EPOR GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;EPOR GO:0007420| brain development EPOR;BCR 4230:[DB06616 DB13875] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13875|Harmaline HNMT common genes common pathways GO:0007420| brain development BCR;HNMT 4231:[DB06616 DB06704] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SRC;ABCB1;LYN;SLC6A2 4232:[DB06616 DB06226] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06226|Nelipepimut-S HLA-A;HLA-A common genes common pathways GO:0060333| interferon-gamma-mediated signaling pathway HLA-A;HCK;CAMK2G GO:0002376| immune system process LYN;HLA-A;SRC;HCK GO:0016032| viral reproduction HLA-A;SRC;HCK;LYN 4233:[DB06616 DB03121] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03121|(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2A GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;PLA2G2A;ABL1 4234:[DB06616 DB07757] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR2;MAP2K1;MAP2K2;SRC;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2 GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;ESR2 4235:[DB06616 DB04367] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04367|Debromohymenialdisine TNK2;CLK1 common genes common pathways GO:0008283| cell proliferation SRC;CLK1 GO:0016477| cell migration SRC;TNK2 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CLK1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;CLK1;CAMK2G;LYN GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CLK1;TNK2;CDK2;LYN;CAMK2G GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;TNK2;HCK GO:0030154| cell differentiation TNK2;CAMK2G;HCK GO:0006468| protein phosphorylation TNK2;MAP3K2;CLK1;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0007165| signal transduction SRC;BCR;MAP2K1;TNK2;LYN GO:0038083| HCK;SRC;ABL1;TNK2;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;TNK2;LYN GO:0042127| regulation of cell proliferation ABL1;SRC;TNK2 GO:0018108| peptidyl-tyrosine phosphorylation CLK1;LYN;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;CLK1 GO:0006897| endocytosis ABL1;TNK2 GO:0045087| innate immune response ABL1;HCK;SRC;LYN;TNK2 4236:[DB06616 DB09322] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09322|Zinc sulfate ALPPL2 common genes common pathways 4237:[DB06616 DB08553] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways GO:0010628| positive regulation of gene expression BRAF;SRC;MAP2K1 GO:0046632| alpha-beta T cell differentiation ABL1;BRAF GO:2000352| negative regulation of endothelial cell apoptosis BRAF;ABL1 GO:0051496| positive regulation of stress fiber assembly BRAF;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;BRAF;MAP2K2;MAP2K1 GO:0045580| regulation of T cell differentiation BRAF;ABL1 GO:0048538| thymus development BRAF;MAP2K1;ABL1 GO:1900026| BRAF;ABL1 GO:0030878| thyroid gland development BRAF;MAP2K1 GO:0007165| signal transduction LYN;BCR;BRAF;SRC;MAP2K1 GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BRAF;BCR;SRC;MAP2K1;HCK;ABL1 GO:0043434| response to peptide hormone stimulus LYN;BRAF GO:0030154| cell differentiation CAMK2G;HCK;BRAF GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;BCR;BRAF;MAP2K2;SRC;ABL1 GO:0000186| activation of MAPKK activity BRAF;MAP3K2 GO:0060324| face development BRAF;MAP2K1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;BRAF;CAMK2G GO:0035556| intracellular signal transduction SRC;BCR;BRAF;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process BRAF;SRC;HCK GO:0050772| positive regulation of axonogenesis MAP2K1;BRAF GO:0042127| regulation of cell proliferation SRC;BRAF;ABL1 GO:0048679| regulation of axon regeneration MAP2K1;BRAF 4238:[DB06616 DB07544] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways GO:0008283| cell proliferation SRC;BCAT1 GO:0000082| G1/S transition of mitotic cell cycle BCAT1;CAMK2G;CDK2 4239:[DB06616 DB04178] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04178|Di-Stearoyl-3-Sn-Phosphatidylcholine BPI;SLC25A4 common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;BPI GO:0016032| viral reproduction HCK;SRC;LYN;SLC25A4 GO:0006810| transport SLC25A4;ABCB1 GO:0055085| transmembrane transport SLC25A4;ABCB1 4240:[DB06616 DB00142] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0045931| positive regulation of mitotic cell cycle ASNS;ABL1 GO:0007399| nervous system development GRIK1;SLC1A2;CAMK2G GO:0042981| regulation of apoptotic process MAP3K2;GLS2;MAP2K2;MAP2K1 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0071260| cellular response to mechanical stimulus GCLC;MAP3K2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;GRIN2A;GRIN1 GO:0009612| response to mechanical stimulus SRC;ASNS GO:0043066| negative regulation of apoptotic process ASNS;GCLC;SRC;HCK GO:0050885| neuromuscular process controlling balance SLC1A3;ABL1;BCR;GRIN2C GO:0050900| leukocyte migration LYN;SLC7A11;SLC16A1;SRC GO:0055114| oxidation-reduction process ALDH18A1;CYP2C8;GLUD2;CYP3A4;AASS;GLUD1 GO:0042493| response to drug GCLM;LYN;GAD2;SLC1A3;SLC1A2;GRIN2A;PFAS;SRC;ABCB1;GAD1;ABAT GO:1901216| GRIN2B;ABL1 GO:0031667| response to nutrient levels SRC;ASNS GO:0051924| regulation of calcium ion transport GRIN3B;CAMK2G GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;GRIN2A;GRIN2C;GRIN1;GRIN2D;CAMK2G;GRIN2B GO:0000082| G1/S transition of mitotic cell cycle BCAT1;CDK2;CAMK2G GO:0006816| calcium ion transport GRIN3A;CAMK2G;GRIN1;GRIN2A GO:0032869| cellular response to insulin stimulus SRC;GCLC;GOT1 GO:0006810| transport GRIN2A;ABCB1;GRIK4;GRIK1;GRIN2B;GRIK2;GRID2;GRIA4;GRIA3;GRIN2C GO:0000186| activation of MAPKK activity GRM1;MAP3K2 GO:0007417| central nervous system development SRC;GRIK1;LYN GO:0031668| cellular response to extracellular stimulus LYN;SLC1A2 GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;ALDH18A1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0007420| brain development SLC7A11;BCR;FPGS GO:0007165| signal transduction LYN;GRM8;GRM4;GRM1;BCR;GRIA2;SRC;GRM7;GRIA1;MAP2K1 GO:0009725| response to hormone stimulus LYN;GCLC GO:0065009| regulation of molecular function GRIN2A;GRM7;GRIN2B;CAMK2G;GRIN2D;GRIN1;GRIN2C GO:0070555| response to interleukin-1 GCLC;SRC GO:0006979| response to oxidative stress GCLM;TAT;SLC7A11;ABL1;GCLC GO:0055085| transmembrane transport GRIK1;GRIK4;ABCB1;GRIK5;SLC16A1;GRIK3;SLC16A10;SLC25A18;SLC25A22;GRIK2;SLC1A7 GO:0000187| activation of MAPK activity MAP3K2;GRM4;GRM1;MAP2K2;MAP2K1 GO:0007596| blood coagulation LYN;GGCX GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GCLC;GCLM GO:0008283| cell proliferation ENPEP;GLUL;SRC;BCAT1;FPGS GO:0043200| response to amino acid stimulus SLC1A2;LYN;ASNS GO:0016477| cell migration ENPEP;SRC GO:0014070| response to organic cyclic compound TAT;LYN GO:0009636| response to toxin SLC7A11;ASNS;LYN GO:0048013| ephrin receptor signaling pathway SRC;GRIN1;GRIN2B;LYN GO:0006464| protein modification process GGCX;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;GCLC 4241:[DB06616 DB07444] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways GO:0010506| regulation of autophagy DAPK1;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;DAPK1 GO:0035556| intracellular signal transduction CAMK2G;LYN;DAPK1;SRC;BCR GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;DAPK1 GO:0006915| apoptotic process ABL1;DAPK1 GO:0046777| protein autophosphorylation CAMK2G;DAPK1;LYN;SRC;BCR;HCK;ABL1 GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;DAPK1;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;LYN;CDK2;DAPK1;CAMK2G GO:0007165| signal transduction DAPK1;LYN;MAP2K1;BCR;SRC 4242:[DB06616 DB11842] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11842|Angiotensin II AGTR1 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;AGTR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AGTR1 GO:0050727| regulation of inflammatory response AGTR1;HCK;LYN GO:0042127| regulation of cell proliferation AGTR1;ABL1;SRC 4243:[DB06616 DB06594] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0042737| drug catabolic process CYP2C9;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0042493| response to drug ABCB1;SRC;HTR2C;CYP1A2;LYN GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C8 GO:0007165| signal transduction LYN;MTNR1B;MTNR1A;HTR2C;MAP2K1;BCR;SRC GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2C8 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;HTR2C;ABL1 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 4244:[DB06616 DB13173] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0043065| positive regulation of apoptotic process ABL1;SRC;IGF2R GO:0042981| regulation of apoptotic process IGF2R;MAP3K2;MAP2K2;MAP2K1 GO:0007165| signal transduction IGF2R;LYN;MAP2K1;BCR;SRC GO:0009791| post-embryonic development IGF2R;ABL1 4245:[DB06616 DB06680] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06680|Asoprisnil PGR common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;PGR;LYN GO:0050847| progesterone receptor signaling pathway SRC;PGR GO:0010629| negative regulation of gene expression MAP2K2;PGR;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent PGR;ABL1 4246:[DB06616 DB00486] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes CYP2C8 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0007165| signal transduction BCR;SRC;MAP2K1;CNR2;LYN;CNR1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0002933| CYP2C8;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2E1 GO:0032496| response to lipopolysaccharide BCR;CNR1;CNR2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;CNR1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006082| organic acid metabolic process CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP2E1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0050728| negative regulation of inflammatory response BCR;CNR2 GO:0006954| inflammatory response HCK;LYN;CNR2 GO:0010976| positive regulation of neuron projection development LYN;CNR1 4247:[DB06616 DB05120] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05120|AT1391 INSR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent INSR;MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 GO:0038083| INSR;LYN;SRC;HCK;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;INSR GO:0023014| signal transduction via phosphorylation event LYN;INSR GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR GO:0018108| peptidyl-tyrosine phosphorylation LYN;INSR;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN;INSR GO:0008284| positive regulation of cell proliferation HCK;INSR;LYN;CDK2 GO:0032148| activation of protein kinase B activity SRC;INSR GO:0000187| activation of MAPK activity INSR;MAP3K2;MAP2K2;MAP2K1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;INSR;CAMK2G;LYN GO:0030335| positive regulation of cell migration LYN;INSR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;INSR GO:0016310| phosphorylation MAP3K2;INSR;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;INSR;MAP3K2 GO:0032869| cellular response to insulin stimulus SRC;INSR 4248:[DB06616 DB09207] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0007165| signal transduction LYN;DRD3;MAP2K1;BCR;DRD2;SRC GO:0030900| forebrain development DRD2;SRC GO:0009636| response to toxin DRD2;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;DRD2;MAP2K2;MAP2K1;ABL1 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;LYN GO:0048678| response to axon injury LYN;DRD2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;DRD3;HCK GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0042493| response to drug ABCB1;DRD2;SRC;LYN;DRD3 4249:[DB06616 DB04094] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FKBP1A GO:0019221| cytokine-mediated signaling pathway FKBP1A;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;ABL1 GO:0001933| negative regulation of protein phosphorylation LYN;FKBP1A 4250:[DB06616 DB04719] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04719|DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:0016236| macroautophagy CSNK2A1;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;CSNK2A1;HCK GO:1901796| CSNK2A1;CDK2 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CSNK2A1 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0007049| cell cycle CSNK2A1;CDK2;SRC GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;CSNK2A1;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CSNK2A1;LYN;CDK2;CAMK2G GO:0007165| signal transduction BCR;SRC;MAP2K1;CSNK2A1;LYN 4251:[DB06616 DB00198] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0006810| transport SLC15A1;ABCB1 GO:0014070| response to organic cyclic compound LYN;ABCC4 GO:0009636| response to toxin LYN;CES1;SLC22A8 GO:0055085| transmembrane transport SLC22A8;SLC15A1;ABCC4;ABCB1 GO:0010033| response to organic substance ABCC4;CDK2 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0002576| platelet degranulation LYN;ABCC4 GO:0006629| lipid metabolic process NEU1;NEU2;CYP3A4 GO:0042493| response to drug ABCB1;SRC;ABCC4;LYN GO:0055114| oxidation-reduction process CYP2C8;ABCC4;CYP3A4 4252:[DB06616 DB04462] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04462|Tetrabromo-2-Benzotriazole CSNK2A1 common genes common pathways GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;CSNK2A1;HCK GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:0016236| macroautophagy SRC;CSNK2A1 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;CSNK2A1;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0016310| phosphorylation MAP3K2;CSNK2A1;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0007165| signal transduction LYN;CSNK2A1;SRC;BCR;MAP2K1 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation CSNK2A1;CAMK2G;MAP2K1 GO:0007049| cell cycle CDK2;CSNK2A1;SRC 4253:[DB06616 DB05996] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways GO:0007165| signal transduction LYN;GPNMB;SRC;BCR;MAP2K1 GO:0030335| positive regulation of cell migration GPNMB;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;GPNMB;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade GPNMB;ABL1;MAP2K1;MAP2K2;SRC GO:0007155| cell adhesion SRC;HCK;ABL1;GPNMB GO:0031954| positive regulation of protein autophosphorylation SRC;GPNMB GO:0001934| positive regulation of protein phosphorylation GPNMB;LYN;ABL1 4254:[DB06616 DB04197] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04197|Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 GO:0043200| response to amino acid stimulus LYN;ARG1 GO:0002376| immune system process LYN;SRC;HCK;ARG1 GO:0043434| response to peptide hormone stimulus ARG1;LYN GO:0002250| adaptive immune response ARG1;LYN GO:0042493| response to drug ABCB1;SRC;ARG1;LYN GO:0045087| innate immune response ABL1;ARG1;SRC;HCK;LYN GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;ARG1 GO:0048678| response to axon injury ARG1;LYN GO:0032496| response to lipopolysaccharide ARG1;BCR 4255:[DB06616 DB13894] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13894|Agkistrodon piscivorus antivenin PLA2G10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G10 GO:0007411| axon guidance PLA2G10;SRC 4256:[DB06616 DB05915] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05915|MYO-029 MSTN common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC;MSTN GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MSTN;SRC;MAP2K2;MAP2K1 GO:0051602| response to electrical stimulus SRC;MSTN GO:0042981| regulation of apoptotic process MAP3K2;MSTN;MAP2K2;MAP2K1 4257:[DB06616 DB03381] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03381|Hexadecanal RHO;DBI common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;RHO GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;RHO;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR 4258:[DB06616 DB07981] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0006979| response to oxidative stress ABL1;PTGS1 GO:0006954| inflammatory response HCK;PTGS1;LYN GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C8 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC 4259:[DB06616 DB09285] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0006928| cellular component movement LTB4R;MAP2K1 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0034605| cellular response to heat LYN;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration TBXA2R;ABL1 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0007165| signal transduction MAP2K1;BCR;SRC;TBXA2R;LTB4R;LYN GO:0065009| regulation of molecular function TBXA2R;CAMK2G GO:0070542| response to fatty acid SRC;PTGS2 GO:0042493| response to drug LYN;PTGS2;TBXA2R;SRC;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;ALOX5;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006954| inflammatory response TBXA2R;HCK;ALOX5;LYN;LTB4R;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;TBXA2R;BCR GO:0042127| regulation of cell proliferation SRC;ABL1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0071222| cellular response to lipopolysaccharide TBXA2R;ABL1;BCR;SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 4260:[DB06616 DB03048] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DPYD 4261:[DB06616 DB01106] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways GO:0006954| inflammatory response HRH1;LYN;HCK GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0007165| signal transduction LYN;HRH1;SRC;BCR;NTSR2;MAP2K1 4262:[DB06616 DB01210] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0045453| bone resorption ADRB2;SRC GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction BCR;SRC;ADRB1;MAP2K1;LYN;ADRB2 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 4263:[DB06616 DB02556] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:0001934| positive regulation of protein phosphorylation ABL1;CRH;LYN GO:0050900| leukocyte migration LYN;SRC;SLC7A5 GO:0042493| response to drug ABCB1;SRC;LYN;CRH GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;CRH GO:0006954| inflammatory response CRH;LYN;HCK GO:0007275| multicellular organismal development CDK2;CAMK2G;SLC7A5 GO:0007399| nervous system development CAMK2G;SLC7A5 GO:0008284| positive regulation of cell proliferation CRH;LYN;CDK2;HCK GO:0055085| transmembrane transport ABCB1;SLC16A10 GO:0010628| positive regulation of gene expression MAP2K1;SRC;CRH GO:0006810| transport ABCB1;SLC7A5 GO:0030154| cell differentiation CAMK2G;SLC7A5;HCK GO:0008202| steroid metabolic process CYP2C8;CRH;CYP3A4 GO:0007165| signal transduction CRH;LYN;MAP2K1;SRC;BCR 4264:[DB06616 DB06217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0065009| regulation of molecular function KCNA5;CAMK2G GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006813| potassium ion transport KCNA5;KCND3;KCNH2;CDK2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0010033| response to organic substance CDK2;KCNA5 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0055085| transmembrane transport KCNA5;KCND3;SCN5A;ABCB1;KCNH2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0009612| response to mechanical stimulus SRC;KCNA5 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0042542| response to hydrogen peroxide KCNA5;SRC GO:0051259| protein oligomerization KCNA5;CAMK2G GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 4265:[DB06616 DB02570] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02570|PD150606 CAPNS1 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CAPNS1;CDK2;LYN 4266:[DB06616 DB07960] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways GO:0006629| lipid metabolic process NEU2;CYP3A4 4267:[DB06616 DB02266] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;SRC GO:0050728| negative regulation of inflammatory response PPARA;BCR GO:0006954| inflammatory response PTGS1;HCK;PTGS2;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process CYP3A4;AKR1C3;PTGS2;CYP2C8;PTGS1 GO:0042493| response to drug SRC;ABCB1;PTGS2;PPARG;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;AR;PPARA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;AR;MAP3K2;CDK2;PPARG;PPARA GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0007507| heart development PPARG;PPARA;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;CDK2;AR GO:0045087| innate immune response SRC;HCK;ABL1;PPARG;LYN GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PTGS1;PPARG;CYP3A4;PPARA;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2;PPARG GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;AKR1C3;AR;HCK GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0042327| positive regulation of phosphorylation AR;LYN GO:0009612| response to mechanical stimulus PPARG;SRC GO:0051259| protein oligomerization CAMK2G;AR GO:0042127| regulation of cell proliferation PTGS2;ABL1;PTGS1;SRC GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0010033| response to organic substance CDK2;PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation AR;MAP2K1;PPARG;LYN;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC;AKR1C3 GO:0032868| response to insulin stimulus PPARA;LYN GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0030216| keratinocyte differentiation MAP2K1;AKR1C3 GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0014070| response to organic cyclic compound PTGS2;LYN;PPARG GO:0007165| signal transduction LYN;PPARG;AR;MAP2K1;SRC;BCR GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006810| transport ABCB1;TTR;AR GO:0034605| cellular response to heat LYN;PTGS2 GO:0008202| steroid metabolic process CYP2C8;AKR1C3;CYP3A4 4268:[DB06616 DB02377] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0042493| response to drug ABCB1;SRC;PNP;LYN GO:0032496| response to lipopolysaccharide BCR;GCH1 4269:[DB06616 DB12305] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3;SLC6A4 GO:0009636| response to toxin SLC6A4;LYN GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;MAP2K1;SRC GO:0006810| transport ABCB1;SLC6A2 GO:0007420| brain development SLC6A4;BCR GO:0042493| response to drug SLC6A2;LYN;ABCB1;SRC;SLC6A4;SLC6A3 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 4270:[DB06616 DB01209] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01209|Dezocine OPRM1;OPRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;OPRM1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0007165| signal transduction OPRM1;LYN;BCR;SRC;MAP2K1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;OPRK1;ABL1 GO:0032496| response to lipopolysaccharide OPRM1;BCR 4271:[DB06616 DB01619] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01619|Phenindamine HRH1 common genes common pathways GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0007165| signal transduction HRH1;LYN;MAP2K1;BCR;SRC 4272:[DB06616 DB05892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05892|RI 624 NGF common genes common pathways GO:0010628| positive regulation of gene expression NGF;SRC;MAP2K1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;NGF;LYN GO:0000186| activation of MAPKK activity MAP3K2;NGF GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;NGF GO:0048011| nerve growth factor receptor signaling pathway NGF;SRC GO:0043065| positive regulation of apoptotic process NGF;ABL1;SRC GO:0043066| negative regulation of apoptotic process NGF;HCK;SRC GO:0050772| positive regulation of axonogenesis MAP2K1;NGF 4273:[DB06616 DB07425] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07425|Sobetirome THRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;THRB 4274:[DB06616 DB02942] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways GO:0006897| endocytosis ABL1;EEA1 4275:[DB06616 DB12752] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12752|Bucindolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 4276:[DB06616 DB01577] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;CDK2;LYN GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0055114| oxidation-reduction process CYP3A4;MAOA;MAOB;CYP2D6;CYP2C8 GO:0042493| response to drug LYN;SLC6A2;MAOB;SLC6A3;SLC6A4;ABCB1;SRC GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0030168| platelet activation ADRA2A;SRC;ADRA2C;LYN;ADRA2B GO:0006810| transport SLC6A2;ABCB1 GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007420| brain development SLC6A4;BCR GO:0007165| signal transduction ADRA2C;LYN;ADRA2B;TAAR1;ADRA2A;BCR;SRC;MAP2K1 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0006855| drug transmembrane transport SLC18A1;SLC22A3;SLC22A5;ABCB1 GO:0055085| transmembrane transport SLC6A2;SLC22A3;SLC18A1;SLC22A5;SLC18A2;ABCB1;SLC6A3;SLC6A4 GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0009636| response to toxin LYN;SLC18A2;MAOB;SLC6A4 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0006928| cellular component movement MAP2K1;ADRA2A 4277:[DB06616 DB11723] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11723|Dutogliptin DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CDK2;LYN;HCK GO:0007155| cell adhesion DPP4;ABL1;SRC;HCK GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation LYN;DPP4;SRC 4278:[DB06616 DB04153] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;ADH5 GO:0055114| oxidation-reduction process ADH5;CYP2C8;CYP3A4 4279:[DB06616 DB05004] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05004|Peptide YY (3-36) NPY2R;NPY1R;NPY5R;NPY4R common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;NPY5R;CDK2;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;NPY5R GO:0007204| elevation of cytosolic calcium ion concentration NPY2R;ABL1 GO:0007165| signal transduction NPY4R;MAP2K1;NPY5R;BCR;SRC;NPY2R;NPY1R;LYN GO:0065009| regulation of molecular function CAMK2G;NPY2R GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;NPY5R;MAP2K2;SRC 4280:[DB06616 DB05740] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CHRNA7;LYN;CDK2 GO:0006281| DNA repair CDK2;CHRNA4;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC;CHRNA10 GO:0042472| inner ear morphogenesis CHRNA9;BCR;CHRNA10 GO:0006816| calcium ion transport CHRNA10;CHRNA4;CHRNA7;CHRNB2;CHRNA9;CAMK2G GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;LYN GO:0006979| response to oxidative stress ABL1;CHRNA4 GO:0007165| signal transduction CHRNA4;SRC;BCR;CHRNA2;MAP2K1;CHRNA10;CHRNA7;CHRNB2;CHRNA9;LYN GO:0007204| elevation of cytosolic calcium ion concentration CHRNA9;CHRNA10;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;CHRNA7 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1;CHRNA7 4281:[DB06616 DB03756] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;SREBF1;SRC GO:0043434| response to peptide hormone stimulus SREBF1;LYN GO:0008202| steroid metabolic process CYP2C8;SREBF1;CYP3A4;CYP2C9 GO:0070542| response to fatty acid SRC;SREBF1 GO:0007165| signal transduction LYN;PPARG;MAP2K1;SRC;BCR GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0032868| response to insulin stimulus LYN;PPARA GO:0014070| response to organic cyclic compound SREBF1;PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation PPARG;LYN;FABP7;MAP2K1 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARA;CYP3A4;CYP2C9;PPARG;SREBF1 GO:0007399| nervous system development CAMK2G;FABP7 GO:0007507| heart development MAP2K1;RXRA;PPARG;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter SREBF1;CDK2;RXRA;PPARG;PPARA GO:0045087| innate immune response PPARG;LYN;SRC;HCK;ABL1 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0071398| cellular response to fatty acid SREBF1;SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA;CDK2;RXRA;MAP3K2;MAP2K2;SRC;SREBF1;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent SREBF1;RXRG;ABL1;RXRA;RXRB;PPARA;PPARG GO:0042493| response to drug SRC;SREBF1;ABCB1;LYN;PPARG GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0016032| viral reproduction RXRA;LYN;SRC;HCK GO:0050728| negative regulation of inflammatory response PPARA;BCR 4282:[DB06616 DB00399] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction LYN;SRC;FDPS;HCK GO:0042493| response to drug ABCC1;LYN;SRC;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C8 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 4283:[DB06616 DB06362] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways GO:0030900| forebrain development TOP2B;SRC GO:0006974| response to DNA damage stimulus ABL1;TOP2A;LYN;CDK2 GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 4284:[DB06616 DB04768] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;TPK1;MAP3K2 4285:[DB06616 DB03052] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;TBXAS1;CYP3A4 GO:0006629| lipid metabolic process TBXAS1;CYP3A4 4286:[DB06616 DB00437] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00437|Allopurinol XDH;AOX1;XDH;SLC22A8;SLC22A7 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A7;ABCB1;SLC22A8 GO:0017144| drug metabolic process CYP2C8;AOX1;CYP3A4 GO:0010629| negative regulation of gene expression XDH;MAP2K1;MAP2K2 GO:0055114| oxidation-reduction process XDH;AOX1;CYP3A4;CYP2C8 GO:0001933| negative regulation of protein phosphorylation LYN;XDH 4287:[DB06616 DB05241] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05241|XL765 PIK3CA;PIK3CG;PIK3CD;PIK3CB;MTOR common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;MTOR;PIK3CD;PIK3CB;LYN GO:0007420| brain development MTOR;BCR GO:0007050| cell cycle arrest MAP2K1;ABL1;MTOR GO:0002376| immune system process SRC;HCK;PIK3CD;PIK3CG;LYN GO:0032956| regulation of actin cytoskeleton organization ABL1;MTOR GO:1900034| MTOR;CAMK2G GO:0030154| cell differentiation HCK;CAMK2G;PIK3CD GO:0006468| protein phosphorylation CAMK2G;PIK3CG;LYN;CDK2;PIK3CD;MTOR;MAP3K2;ABL1;SRC;PIK3CA;BCR;MAP2K2;HCK;MAP2K1 GO:0071456| cellular response to hypoxia SRC;MTOR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;PIK3CG GO:0030168| platelet activation PIK3CD;PIK3CG;LYN;PIK3CB;SRC;PIK3CA GO:0031295| T cell costimulation SRC;PIK3CA;LYN GO:0016310| phosphorylation PIK3CG;CAMK2G;CDK2;LYN;PIK3CB;PIK3CD;MTOR;MAP3K2;ABL1;PIK3CA;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0030335| positive regulation of cell migration LYN;PIK3CD GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway PIK3CB;LYN;HCK GO:0043406| positive regulation of MAP kinase activity PIK3CG;SRC GO:0007411| axon guidance PIK3CB;PIK3CD;PIK3CA;SRC GO:0009791| post-embryonic development ABL1;MTOR GO:0050853| B cell receptor signaling pathway PIK3CD;LYN;ABL1 GO:0046777| protein autophosphorylation MTOR;LYN;CAMK2G;HCK;SRC;BCR;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;MTOR;PIK3CD;PIK3CB GO:0032868| response to insulin stimulus LYN;MTOR GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MTOR;MAP2K1 GO:0033628| regulation of cell adhesion mediated by integrin PIK3CG;LYN GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;PIK3CB;MAP3K2 GO:0038095| LYN;PIK3CB;PIK3CA GO:0016477| cell migration SRC;PIK3CB GO:0043200| response to amino acid stimulus LYN;MTOR GO:0051496| positive regulation of stress fiber assembly ABL1;MTOR GO:0032148| activation of protein kinase B activity SRC;MTOR GO:0007155| cell adhesion PIK3CB;SRC;HCK;ABL1 GO:0045087| innate immune response ABL1;PIK3CA;SRC;HCK;PIK3CG;LYN;PIK3CB;PIK3CD GO:0006281| DNA repair CDK2;MTOR;ABL1 GO:0006935| chemotaxis MAP2K1;PIK3CD;PIK3CB;PIK3CG GO:0060252| positive regulation of glial cell proliferation LYN;MTOR GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;MTOR;SRC GO:0006897| endocytosis ABL1;PIK3CB;PIK3CG GO:0048010| vascular endothelial growth factor receptor signaling pathway PIK3CB;PIK3CA;SRC GO:0043542| endothelial cell migration PIK3CA;ABL1 GO:0001932| regulation of protein phosphorylation PIK3CG;LYN;MTOR;MAP2K1 GO:0030838| positive regulation of actin filament polymerization HCK;MTOR GO:0001933| negative regulation of protein phosphorylation LYN;MTOR GO:0038096| ABL1;HCK;SRC;PIK3CA;PIK3CB;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;MTOR GO:0038128| SRC;PIK3CA GO:0002250| adaptive immune response PIK3CG;PIK3CB;LYN;PIK3CD;PIK3CA GO:0051897| positive regulation of protein kinase B signaling cascade SRC;PIK3CA;PIK3CB;PIK3CG;MTOR;PIK3CD GO:0010976| positive regulation of neuron projection development MTOR;LYN GO:0006954| inflammatory response PIK3CG;PIK3CB;LYN;PIK3CD;PIK3CA;HCK GO:2000811| negative regulation of anoikis PIK3CA;SRC GO:0050900| leukocyte migration PIK3CB;LYN;SRC;PIK3CA GO:0006914| autophagy ABL1;PIK3CB GO:0001934| positive regulation of protein phosphorylation MTOR;LYN;ABL1 GO:0006909| phagocytosis ABL1;HCK;PIK3CA GO:1901216| ABL1;MTOR GO:0007173| epidermal growth factor receptor signaling pathway PIK3CA;SRC;ABL1 4288:[DB06616 DB00473] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A;SCN10A 4289:[DB06616 DB02467] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways GO:0007596| blood coagulation RAB5A;LYN GO:0030100| regulation of endocytosis ABL1;RAB5A GO:0006909| phagocytosis RAB5A;ABL1;HCK GO:0006897| endocytosis RAB5A;ABL1 GO:0045056| transcytosis SRC;RAB5A 4290:[DB06616 DB01046] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CBR1;CYP3A4 GO:0006810| transport CLCN2;ABCB1 GO:0055085| transmembrane transport ABCB1;CLCN2 GO:0055114| oxidation-reduction process CYP3A4;CBR1;CYP2C8 4291:[DB06616 DB08103] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 4292:[DB06616 DB03147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0001933| negative regulation of protein phosphorylation LYN;XDH GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0034599| cellular response to oxidative stress ABL1;GSR;TXNRD1 GO:0006805| xenobiotic metabolic process CYP2C8;POR;CYB5R3;NQO1;CYP3A4;NQO2 GO:0043066| negative regulation of apoptotic process NQO1;POR;SRC;HCK GO:0002576| platelet degranulation LYN;CYB5R1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;AIFM1 GO:0071732| cellular response to nitric oxide CDK2;AIFM1 GO:0006629| lipid metabolic process CYB5R3;ACOX1;CYP3A4;FDXR;ACADM;ACADS;ACAD8;CYB5R1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;CDK2 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;NOS1;CDK2 GO:0042493| response to drug POR;ABCB1;SRC;LYN;MAOB GO:0042738| exogenous drug catabolic process CYP3A4;NOS1;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;XDH GO:0006355| regulation of transcription, DNA-dependent ACAD8;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process POR;SRC GO:0055114| oxidation-reduction process CYP3A4;ACOX1;NQO1;NOS1;CYB5R3;MAOB;ACADM;MAOA;FDXR;IVD;IL4I1;XDH;NQO2;ACADS;GFER;AIFM1;DAO;DLD;ERO1B;CYP2C8;NDUFA9;GSR;CYB5R1;GCDH;DPYD;POR;TXNRD1;ACAD8 GO:0051602| response to electrical stimulus NQO1;SRC GO:0016032| viral reproduction HCK;SRC;LYN;TPR GO:0051301| cell division CDK2;TPR GO:0034605| cellular response to heat TPR;LYN GO:0008202| steroid metabolic process CYP2C8;CYB5R1;CYB5R3;CYP3A4;FDXR GO:1900034| CAMK2G;TPR GO:0006979| response to oxidative stress NQO1;ABL1 GO:0007165| signal transduction SRC;BCR;TXNRD1;MAP2K1;LYN GO:0009636| response to toxin MAOB;NQO1;LYN;AIFM1 GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0008283| cell proliferation SRC;TXNRD1 GO:0030182| neuron differentiation AIFM1;ABL1;MAP2K1 GO:0006915| apoptotic process ABL1;AIFM1 GO:0007049| cell cycle SRC;CDK2;TPR GO:0006464| protein modification process ABL1;ERO1B GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1;AIFM1 GO:0071375| cellular response to peptide hormone stimulus SRC;POR 4293:[DB06616 DB00235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00235|Milrinone PDE3A common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;PDE3A GO:0042493| response to drug SRC;ABCB1;LYN;PDE3A GO:0006629| lipid metabolic process CYP3A4;PDE3A GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PDE3A GO:0043066| negative regulation of apoptotic process SRC;HCK;PDE3A 4294:[DB06616 DB03485] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03485|Alpha-D-Fucose LTF common genes common pathways GO:0033690| positive regulation of osteoblast proliferation LTF;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1;LTF GO:0002376| immune system process LTF;HCK;SRC;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;LTF GO:0001817| regulation of cytokine production LTF;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;LTF GO:0043066| negative regulation of apoptotic process LTF;HCK;SRC GO:0045087| innate immune response LYN;SRC;HCK;ABL1;LTF 4295:[DB06616 DB14562] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14562|Andexanet alfa TFPI common genes common pathways GO:0007596| blood coagulation LYN;TFPI GO:0032496| response to lipopolysaccharide TFPI;BCR GO:0071222| cellular response to lipopolysaccharide TFPI;ABL1;BCR;SRC 4296:[DB06616 DB08824] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08824|Ioflupane I-123 SLC6A3 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0055085| transmembrane transport SLC6A3;ABCB1 GO:0042493| response to drug SLC6A3;SRC;ABCB1;LYN 4297:[DB06616 DB05252] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;MAP2K1;MAP2K2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NOS2 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;NOS2 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0042127| regulation of cell proliferation NOS2;SRC;ABL1 4298:[DB06616 DB07168] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways GO:0007399| nervous system development CAMK2G;CAMK2B GO:0035556| intracellular signal transduction CAMK2B;LYN;CAMK2G;BCR;SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;CAMK2B;SRC GO:0007275| multicellular organismal development CAMK2B;CAMK2G;CDK2 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2B;CAMK2G GO:0051924| regulation of calcium ion transport CAMK2B;CAMK2G GO:0010976| positive regulation of neuron projection development LYN;CAMK2B GO:0014733| regulation of skeletal muscle adaptation CAMK2B;CAMK2G GO:0065009| regulation of molecular function CAMK2G;CAMK2B GO:0007165| signal transduction LYN;CAMK2B;MAP2K1;SRC;BCR GO:1900034| CAMK2G;CAMK2B GO:0060333| interferon-gamma-mediated signaling pathway HCK;CAMK2B;CAMK2G GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;CAMK2B;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0030154| cell differentiation CAMK2B;CAMK2G;HCK GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MAP3K2;CAMK2B GO:0046777| protein autophosphorylation CAMK2B;LYN;CAMK2G;HCK;SRC;BCR;ABL1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2B;CAMK2G 4299:[DB06616 DB07276] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07276|5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent MAPK8IP1;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MAPK8IP1;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;MAPK8 GO:0043066| negative regulation of apoptotic process HCK;MAPK8;SRC;MAPK8IP1 GO:0043065| positive regulation of apoptotic process ABL1;MAPK8;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;MAPK8;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;MAPK8;CAMK2G;CDK2 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAPK8;MAP2K1 GO:0038095| LYN;MAPK8 GO:0010628| positive regulation of gene expression MAPK8;MAP2K1;SRC GO:0034614| cellular response to reactive oxygen species SRC;MAPK8 GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAPK8;MAP2K1 GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;HCK;MAPK8;ABL1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;MAPK8 GO:0007165| signal transduction SRC;BCR;MAP2K1;MAPK8IP1;LYN 4300:[DB06616 DB01927] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01927|Duroquinone NQO1 common genes common pathways GO:0006979| response to oxidative stress NQO1;ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1;NQO1 GO:0014070| response to organic cyclic compound NQO1;LYN GO:0009636| response to toxin LYN;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process HCK;SRC;NQO1 GO:0051602| response to electrical stimulus SRC;NQO1 GO:0055114| oxidation-reduction process CYP2C8;NQO1;CYP3A4 4301:[DB06616 DB08995] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08995|Diosmin AHR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;AHR;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;AHR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;AHR;CDK2 GO:0006915| apoptotic process ABL1;AHR GO:0009636| response to toxin AHR;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;AHR GO:0007049| cell cycle AHR;CDK2;SRC 4302:[DB06616 DB01851] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01851|Tetrabutylammonium Ion IGKC common genes common pathways GO:0002376| immune system process LYN;IGKC;HCK;SRC GO:0038095| IGKC;LYN GO:0050853| B cell receptor signaling pathway LYN;IGKC;ABL1 GO:0045087| innate immune response LYN;IGKC;HCK;SRC;ABL1 GO:0050900| leukocyte migration SRC;IGKC;LYN GO:0002250| adaptive immune response IGKC;LYN GO:0038096| HCK;SRC;ABL1;LYN;IGKC 4303:[DB06616 DB02545] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02545|Fexaramine NR1H4 common genes common pathways GO:0045087| innate immune response LYN;NR1H4;ABL1;SRC;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR1H4 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;NR1H4 GO:0071398| cellular response to fatty acid SRC;NR1H4 GO:0043066| negative regulation of apoptotic process HCK;SRC;NR1H4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;NR1H4 GO:0046628| positive regulation of insulin receptor signaling pathway SRC;NR1H4 GO:0006954| inflammatory response LYN;NR1H4;HCK GO:0050728| negative regulation of inflammatory response BCR;NR1H4 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1H4 GO:0007165| signal transduction SRC;BCR;MAP2K1;NR1H4;LYN GO:0002376| immune system process HCK;SRC;NR1H4;LYN 4304:[DB06616 DB03619] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;NR1H4;GPBAR1;LYN GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0002376| immune system process NR1H4;LYN;SRC;HCK GO:0032869| cellular response to insulin stimulus GSTP1;SRC GO:0006810| transport SLC10A1;SLC10A2;ABCB1;ABCB11 GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0055085| transmembrane transport ABCB1;SLC10A2;SLC10A1;ABCB11;SLCO1A2 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;GSTP1;MAP2K1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1 GO:0009636| response to toxin GSTP1;LYN GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0045087| innate immune response SRC;HCK;ABL1;NR1H4;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;CDK2 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;GSTP1;ABL1;NR1H4 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK;NR1H4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;GSTP1 GO:0071398| cellular response to fatty acid NR1H4;SRC GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1;NR1H4 GO:0046628| positive regulation of insulin receptor signaling pathway SRC;NR1H4 GO:0006954| inflammatory response HCK;NR1H4;LYN GO:0050728| negative regulation of inflammatory response NR1H4;BCR GO:0016032| viral reproduction LYN;SRC;SLC10A1;HCK GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1H4 GO:0014003| oligodendrocyte development GSTP1;LYN GO:0031667| response to nutrient levels GSTP1;SRC 4305:[DB06616 DB06374] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06374|Elacestrant ESR1 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0060065| uterus development ESR1;SRC GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;ESR1;MAP3K2 GO:0008209| androgen metabolic process CYP3A4;ESR1 4306:[DB06616 DB06082] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06082|PX-478 HIF1A common genes common pathways GO:0071456| cellular response to hypoxia SRC;HIF1A GO:0030154| cell differentiation HCK;HIF1A;CAMK2G GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;HIF1A GO:2000378| negative regulation of reactive oxygen species metabolic process HIF1A;BCR GO:0001922| B-1 B cell homeostasis ABL1;HIF1A GO:0010628| positive regulation of gene expression SRC;MAP2K1;HIF1A GO:0042127| regulation of cell proliferation ABL1;HIF1A;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;HIF1A GO:0010634| positive regulation of epithelial cell migration HIF1A;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;HIF1A GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;HIF1A GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;HIF1A;MAP2K2;SRC 4307:[DB06616 DB01723] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;SRC GO:0001933| negative regulation of protein phosphorylation FKBP1A;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;FKBP1A GO:0019221| cytokine-mediated signaling pathway HCK;FKBP1A 4308:[DB06616 DB01407] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0042493| response to drug SRC;ABCB1;CYP1A1;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TNF GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;TNF;MAP2K1;SRC;MAP2K2 GO:0050900| leukocyte migration TNF;LYN;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2C8 GO:0001934| positive regulation of protein phosphorylation LYN;TNF;ABL1 GO:0048011| nerve growth factor receptor signaling pathway SRC;NGF GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process NGF;SRC GO:0006954| inflammatory response HCK;LYN;TNF GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0000165| MAPKKK cascade TNF;CAMK2G;MAP2K1;MAP2K2 GO:0032496| response to lipopolysaccharide CYP1A1;BCR GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0042127| regulation of cell proliferation TNF;ABL1;SRC GO:0001932| regulation of protein phosphorylation TNF;LYN;MAP2K1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0009615| response to virus SRC;CYP1A1;TNF GO:0071222| cellular response to lipopolysaccharide TNF;ABL1;SRC;BCR GO:0043065| positive regulation of apoptotic process NGF;TNF;SRC;ABL1 GO:0050727| regulation of inflammatory response TNF;LYN;HCK GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN;TNF GO:0043066| negative regulation of apoptotic process HCK;SRC;NGF GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TNF GO:0050772| positive regulation of axonogenesis NGF;MAP2K1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0008283| cell proliferation SRC;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;LYN GO:0009636| response to toxin LYN;CYP1A1 GO:0002933| CYP2C8;CYP3A4;CYP1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ABL1;MAP2K1;MAP2K2;SRC GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TNF;MAP3K2 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;ADRB2 GO:0010628| positive regulation of gene expression TNF;NGF;MAP2K1;SRC GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0010033| response to organic substance CYP1A1;CDK2;TNF GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;NGF;HCK GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0000186| activation of MAPKK activity NGF;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0045453| bone resorption ADRB2;SRC GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0051222| positive regulation of protein transport TNF;SRC GO:0007165| signal transduction LYN;ADRB2;ADRB3;BCR;ADRB1;SRC;MAP2K1 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2C8 4309:[DB06616 DB01439] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;SRC;BCR GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;OPRD1 GO:0007165| signal transduction SRC;BCR;MAP2K1;OPRK1;OPRM1;OPRD1;LYN GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;OPRM1 GO:0032868| response to insulin stimulus OPRK1;LYN 4310:[DB06616 DB11324] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11324|Nonivamide TRPV1 common genes common pathways GO:0055085| transmembrane transport TRPV1;ABCB1 GO:0006810| transport ABCB1;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TRPV1 GO:0043434| response to peptide hormone stimulus LYN;TRPV1 GO:0034605| cellular response to heat TRPV1;LYN GO:0065009| regulation of molecular function TRPV1;CAMK2G GO:0006816| calcium ion transport CAMK2G;TRPV1 GO:0006954| inflammatory response LYN;HCK;TRPV1 GO:0006629| lipid metabolic process CYP3A4;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;CDK2 GO:0043065| positive regulation of apoptotic process TRPV1;SRC;ABL1 4311:[DB06616 DB07497] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways GO:0010629| negative regulation of gene expression MAP2K2;PC;MAP2K1 GO:0006629| lipid metabolic process CYP3A4;PC 4312:[DB06616 DB05737] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05737|Varespladib methyl PLA2G2A;PLA2G10 common genes common pathways GO:0007411| axon guidance SRC;PLA2G10 GO:0070374| positive regulation of ERK1 and ERK2 cascade PLA2G2A;ABL1;MAP2K1;MAP2K2;SRC GO:0006629| lipid metabolic process CYP3A4;PLA2G10;PLA2G2A 4313:[DB06616 DB03379] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03379|2-Carboxyethylphosphonic Acid TPI1 common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;TPI1 4314:[DB06616 DB07707] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07707|(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0060065| uterus development SRC;ESR1 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;NCOA2 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1;NCOA2 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction ESR1;LYN;SRC;BCR;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 4315:[DB06616 DB13146] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport SLC7A7;ABCB1;GRIN2A;GRIA4;GRIA3;GRIN2C;GRIN2B GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007165| signal transduction BCR;SRC;GRIA2;GRIA1;MAP2K1;LYN GO:0065009| regulation of molecular function GRIN2A;GRIN2B;CAMK2G;GRIN1;GRIN2D;GRIN2C GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0055085| transmembrane transport ABCC4;ABCB1 GO:0014070| response to organic cyclic compound LYN;ABCC4 GO:0048013| ephrin receptor signaling pathway SRC;GRIN2B;LYN;GRIN1 GO:0010033| response to organic substance CDK2;ABCC4 GO:1901529| ABCB1 GO:0002576| platelet degranulation ABCC4;LYN GO:0043065| positive regulation of apoptotic process GRIN2A;ABL1;SRC;GRIN1 GO:0050885| neuromuscular process controlling balance GRIN2C;ABL1;BCR GO:0050900| leukocyte migration SLC7A7;SRC;LYN GO:0055114| oxidation-reduction process CYP2C8;ABCC4;CYP3A4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug LYN;GRIN2A;ABCB1;SRC;ABCC4 GO:1901216| ABL1;GRIN2B GO:0051924| regulation of calcium ion transport GRIN3B;CAMK2G GO:0000165| MAPKKK cascade GRIN2C;GRIN2D;GRIN1;CAMK2G;GRIN2B;MAP2K2;MAP2K1;GRIN2A GO:0006816| calcium ion transport GRIN3A;CAMK2G;GRIN1;GRIN2A GO:0016032| viral reproduction SRC;HCK;SLC1A5;LYN 4316:[DB06616 DB08346] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08346|(5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE HSP90AB1 common genes common pathways GO:1900034| CAMK2G;HSP90AB1 GO:0071902| positive regulation of protein serine/threonine kinase activity HSP90AB1;SRC;MAP2K2;MAP2K1 GO:0010033| response to organic substance HSP90AB1;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;HSP90AB1 GO:0006805| xenobiotic metabolic process HSP90AB1;CYP3A4;CYP2C8 GO:0045597| positive regulation of cell differentiation HSP90AB1;MAP2K1 GO:0038096| ABL1;HCK;SRC;LYN;HSP90AB1 GO:0042493| response to drug SRC;ABCB1;LYN;HSP90AB1 4317:[DB06616 DB07678] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07678|(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;SRC GO:0007165| signal transduction LYN;ESR1;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0060065| uterus development ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;NCOA2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 4318:[DB06616 DB02169] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02169|9,10-Deepithio-9,10-Didehydroacanthifolicin PPP1CC common genes common pathways GO:0051301| cell division PPP1CC;CDK2 GO:0030182| neuron differentiation PPP1CC;ABL1;MAP2K1 GO:0006470| protein dephosphorylation PPP1CC;CAMK2G GO:0007049| cell cycle SRC;PPP1CC;CDK2 4319:[DB06616 DB05790] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05790|SR 140333 TACR1 common genes common pathways GO:0051496| positive regulation of stress fiber assembly ABL1;TACR1 GO:0014070| response to organic cyclic compound TACR1;LYN GO:0007165| signal transduction LYN;TACR1;BCR;SRC;MAP2K1 GO:0009725| response to hormone stimulus TACR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration TACR1;ABL1 GO:0006954| inflammatory response HCK;LYN;TACR1 GO:0051602| response to electrical stimulus TACR1;SRC GO:0010634| positive regulation of epithelial cell migration SRC;TACR1 4320:[DB06616 DB01429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0038095| LYN;CALM1 GO:0055085| transmembrane transport ABCB1;SCN5A;CALM1 GO:0071902| positive regulation of protein serine/threonine kinase activity CALM1;MAP2K1;MAP2K2;SRC GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0002576| platelet degranulation CALM1;LYN;ORM1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006954| inflammatory response LYN;ORM1;HCK GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0000165| MAPKKK cascade CAMK2G;CALM1;MAP2K2;MAP2K1 4321:[DB06616 DB08080] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08080|LATRUNCULIN B ACTA1;MKL1;SPIRE2 common genes common pathways GO:0009612| response to mechanical stimulus ACTA1;SRC GO:0030036| actin cytoskeleton organization ABL1;BCR;SPIRE2 GO:0006355| regulation of transcription, DNA-dependent ABL1;MKL1 GO:0010628| positive regulation of gene expression ACTA1;SRC;MAP2K1 4322:[DB06616 DB09338] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0050900| leukocyte migration SLC16A1;SRC;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;AQP1 GO:0042493| response to drug SRC;ABCB1;AQP1;LYN GO:0006629| lipid metabolic process CYP3A4;SLC16A1;PCK1 GO:0071260| cellular response to mechanical stimulus AQP1;MAP3K2 GO:0071732| cellular response to nitric oxide CDK2;AQP1 GO:0071300| cellular response to retinoic acid LYN;AQP1;PCK1 GO:0043066| negative regulation of apoptotic process AQP1;SRC;HCK GO:0032496| response to lipopolysaccharide BCR;ALPL;PCK1 GO:0070301| cellular response to hydrogen peroxide AQP1;ABL1 GO:0032868| response to insulin stimulus PCK1;LYN GO:0055085| transmembrane transport ABCB1;AQP1;SLC16A1 GO:0006813| potassium ion transport CDK2;AQP1 GO:0071456| cellular response to hypoxia PCK1;AQP1;SRC GO:0032869| cellular response to insulin stimulus SRC;PCK1 4323:[DB06616 DB07315] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways 4324:[DB06616 DB09418] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways GO:0055085| transmembrane transport SLC5A5;ABCB1 GO:0006810| transport ABCB1;SLC5A5 GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 4325:[DB06616 DB04636] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04636|Glutamine t-butyl ester QPCT common genes common pathways GO:0006464| protein modification process ABL1;QPCT 4326:[DB06616 DB04676] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04676|Dansyllysine IGHA2 common genes common pathways GO:0050853| B cell receptor signaling pathway LYN;ABL1;IGHA2 GO:0002376| immune system process LYN;HCK;IGHA2;SRC GO:0002250| adaptive immune response IGHA2;LYN GO:0050900| leukocyte migration IGHA2;SRC;LYN GO:0045087| innate immune response HCK;IGHA2;SRC;ABL1;LYN 4327:[DB06616 DB07082] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07082|1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL NR1H2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR1H2 GO:0006355| regulation of transcription, DNA-dependent NR1H2;ABL1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NR1H2 GO:0045893| positive regulation of transcription, DNA-dependent NR1H2;MAP3K2;CDK2;MAP2K1;MAP2K2;SRC GO:0010628| positive regulation of gene expression NR1H2;SRC;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent NR1H2;SRC 4328:[DB06616 DB03276] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways GO:0035635| entry of bacterium into host cell SRC;GRB2 GO:0045087| innate immune response ABL1;GRB2;SRC;HCK;LYN GO:0042127| regulation of cell proliferation GRB2;ABL1;SRC GO:0030838| positive regulation of actin filament polymerization GRB2;HCK GO:0007265| Ras protein signal transduction GRB2;CDK2 GO:0016032| viral reproduction GRB2;HCK;SRC;LYN GO:0042770| signal transduction in response to DNA damage GRB2;ABL1 GO:0038128| GRB2;SRC GO:0038096| GRB2;ABL1;HCK;SRC;LYN GO:0051897| positive regulation of protein kinase B signaling cascade GRB2;SRC GO:0000165| MAPKKK cascade GRB2;MAP2K1;MAP2K2;CAMK2G GO:0038083| SRC;HCK;ABL1;GRB2;LYN GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;GRB2 GO:0050900| leukocyte migration LYN;GRB2;SRC GO:0065009| regulation of molecular function GRB2;CAMK2G GO:0031295| T cell costimulation GRB2;SRC;LYN GO:0030154| cell differentiation GRB2;HCK;CAMK2G GO:0007411| axon guidance SRC;GRB2 GO:0038095| GRB2;LYN GO:0016477| cell migration GRB2;SRC 4329:[DB06616 DB01127] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP2C8;NR1I2;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0060065| uterus development CYP19A1;SRC GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042493| response to drug ABCB1;SRC;CYP2E1;LYN GO:0042738| exogenous drug catabolic process CYP2C8;NR1I2;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR1I2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;MAP3K2;NR1I2;CDK2 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP19A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;NR1I2 GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;NR1I2;CYP3A4;CYP2E1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;NR1I2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1I2 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 4330:[DB06616 DB02552] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;FDPS GO:0016032| viral reproduction LYN;SRC;FDPS;HCK GO:0006629| lipid metabolic process FDPS;CYP3A4 4331:[DB06616 DB08699] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes CAMK2G common pathways GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1 GO:0006470| protein dephosphorylation CAMK2G GO:0046777| protein autophosphorylation CAMK2G;LYN;SRC;BCR;HCK;ABL1 GO:0030154| cell differentiation CAMK2G;HCK GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0065009| regulation of molecular function CAMK2G GO:0060333| interferon-gamma-mediated signaling pathway HCK;CAMK2G GO:1900034| CAMK2G GO:0014733| regulation of skeletal muscle adaptation CAMK2G GO:0051924| regulation of calcium ion transport CAMK2G GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2 GO:0000082| G1/S transition of mitotic cell cycle CAMK2G;CDK2 GO:0006816| calcium ion transport CAMK2G GO:1901897| CAMK2G GO:0007275| multicellular organismal development CDK2;CAMK2G GO:0051259| protein oligomerization CAMK2G GO:0007399| nervous system development CAMK2G GO:0030073| insulin secretion CAMK2G GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC 4332:[DB06616 DB07916] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;CASP1;LYN GO:0050715| positive regulation of cytokine secretion CASP1;SRC GO:0006915| apoptotic process CASP1;ABL1 GO:0051882| mitochondrial depolarization ABL1;CASP1 GO:0071260| cellular response to mechanical stimulus MAP3K2;CASP1 GO:0042981| regulation of apoptotic process MAP3K2;CASP1;MAP2K2;MAP2K1 GO:0050727| regulation of inflammatory response HCK;CASP1;LYN GO:0071222| cellular response to lipopolysaccharide CASP1;BCR;SRC;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CASP1 GO:0032496| response to lipopolysaccharide BCR;CASP1 GO:0010506| regulation of autophagy CASP1;ABL1 4333:[DB06616 DB03800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways GO:0042493| response to drug TYMS;LYN;SRC;ABCB1 GO:0009636| response to toxin TYMS;LYN GO:0014070| response to organic cyclic compound TYMS;LYN 4334:[DB06616 DB03956] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways GO:0007165| signal transduction LYN;PLCD1;MAP2K1;BCR;SRC GO:0042127| regulation of cell proliferation SRC;PLCD1;ABL1 GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;PLCD1 GO:0006629| lipid metabolic process PLCD1;CYP3A4 4335:[DB06616 DB02673] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0006260| DNA replication CDK2;ACHE GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ABL1;HCK;SRC;ACHE 4336:[DB06616 DB07356] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;LYN;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK GO:0007155| cell adhesion DPP4;ABL1;SRC;HCK 4337:[DB06616 DB00697] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00697|Tizanidine ADRA2A;ADRA2B;ADRA2C;NISCH;CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0007165| signal transduction ADRA2C;ADRA2B;LYN;SRC;BCR;MAP2K1;ADRA2A GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0030168| platelet activation ADRA2A;SRC;ADRA2C;LYN;ADRA2B GO:0030336| negative regulation of cell migration BCR;NISCH GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0006915| apoptotic process ABL1;NISCH GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;ADRA2A GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2B;ADRA2C GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR;NISCH GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;LYN;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 4338:[DB06616 DB05052] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05052|MF101 ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR2;MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2 GO:0007165| signal transduction LYN;ESR2;MAP2K1;BCR;SRC 4339:[DB06616 DB06243] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06243|Eflornithine ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;ODC1 GO:0009615| response to virus SRC;ODC1 4340:[DB06616 DB00195] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0042737| drug catabolic process CYP2D6;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug SRC;ABCB1;CYP1A2;LYN GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0007165| signal transduction LYN;ADRB2;ADRB1;SRC;BCR;MAP2K1 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP2C8 GO:0045453| bone resorption ADRB2;SRC GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 GO:0009791| post-embryonic development CYP1A2;ABL1 4341:[DB06616 DB03032] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03032|S-Octylglutathione GSTM4 common genes common pathways 4342:[DB06616 DB03628] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03628|ISO24 SRC common genes SRC common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0045785| positive regulation of cell adhesion SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007411| axon guidance SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;BCR;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0071456| cellular response to hypoxia SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0048477| oogenesis SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0031295| T cell costimulation LYN;SRC GO:0036120| SRC GO:0007417| central nervous system development SRC;LYN GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0002376| immune system process LYN;SRC;HCK GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0034332| adherens junction organization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0050900| leukocyte migration LYN;SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0038083| ABL1;SRC;HCK;LYN GO:0042493| response to drug SRC;ABCB1;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038096| SRC;HCK;ABL1;LYN GO:0016032| viral reproduction SRC;HCK;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:0086098| SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response SRC;HCK;ABL1;LYN GO:0007155| cell adhesion ABL1;SRC;HCK GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 4343:[DB06616 DB04789] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0006810| transport ABCB1;ABCC2 GO:0042493| response to drug ABCC2;ABCB1;SRC;LYN GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;ABCC2 GO:0032496| response to lipopolysaccharide BCR;ABCC2 4344:[DB06616 DB07893] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07893|PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE IGKC common genes common pathways GO:0002376| immune system process LYN;IGKC;HCK;SRC GO:0038095| IGKC;LYN GO:0050853| B cell receptor signaling pathway ABL1;IGKC;LYN GO:0045087| innate immune response ABL1;HCK;SRC;LYN;IGKC GO:0050900| leukocyte migration SRC;IGKC;LYN GO:0038096| HCK;SRC;ABL1;LYN;IGKC GO:0002250| adaptive immune response LYN;IGKC 4345:[DB06616 DB02979] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02979|N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;NOS3 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN GO:0043542| endothelial cell migration ABL1;NOS3 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 4346:[DB06616 DB01452] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01452|Diamorphine OPRM1;OPRK1;OPRD1;CES1 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0071222| cellular response to lipopolysaccharide ABL1;OPRK1;BCR;SRC GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;OPRD1 GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0007165| signal transduction LYN;OPRM1;OPRD1;OPRK1;SRC;BCR;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;OPRM1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0009636| response to toxin LYN;CES1 GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN 4347:[DB06616 DB01363] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA2A;HCK GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;SRC;ADRA2A GO:0042493| response to drug SLC6A3;SLC6A4;SRC;ABCB1;LYN;SLC6A2;MAOB GO:0055114| oxidation-reduction process CYP2C8;MAOA;MAOB;CYP3A4 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0006810| transport SLC6A2;ABCB1 GO:0030168| platelet activation ADRA2B;LYN;ADRA2C;SRC;ADRA2A GO:0045453| bone resorption SRC;ADRB2 GO:0007420| brain development BCR;SLC6A4 GO:0007165| signal transduction ADRA2C;ADRB2;ADRA2B;LYN;ADRA2A;ADRB3;BCR;ADRB1;SRC;MAP2K1 GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0009636| response to toxin MAOB;LYN;SLC18A2;SLC6A4 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;ADRA2B GO:0006855| drug transmembrane transport SLC18A1;ABCB1 GO:0055085| transmembrane transport SLC18A2;SLC6A2;SLC18A1;SLC6A3;SLC6A4;ABCB1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;SLC6A4 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 GO:0010033| response to organic substance SLC6A4;CDK2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC 4348:[DB06616 DB04540] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;VDR;LYN GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;SRC;VDR GO:0010628| positive regulation of gene expression MAP2K1;VDR;SRC GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0007165| signal transduction LYN;NR1I3;VDR;MAP2K1;SRC;BCR GO:0002376| immune system process CLEC4E;LYN;SRC;HCK GO:0050715| positive regulation of cytokine secretion SRC;CLEC4E GO:0071456| cellular response to hypoxia SRC;RORA GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0050728| negative regulation of inflammatory response RORA;BCR GO:0006816| calcium ion transport CAMK2G;VDR GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCG2;ABCB1;SRC;LYN GO:0006355| regulation of transcription, DNA-dependent VDR;ABL1;NR1I3;RORA GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;RORA;MAP2K1;SRC;MAP2K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VDR GO:0045087| innate immune response LYN;CLEC4E;ABL1;SRC;HCK GO:0006805| xenobiotic metabolic process CYP2C8;RORA;CYP3A4 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;CLEC4E;LYN GO:0007275| multicellular organismal development CAMK2G;CDK2;VDR GO:1901529| ABCB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade RORA;ABL1 4349:[DB06616 DB02381] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02381|nor-NOHA ARG1 common genes common pathways GO:0002376| immune system process LYN;SRC;HCK;ARG1 GO:0043434| response to peptide hormone stimulus LYN;ARG1 GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 GO:0043200| response to amino acid stimulus ARG1;LYN GO:0045087| innate immune response ARG1;ABL1;SRC;HCK;LYN GO:0071560| cellular response to transforming growth factor beta stimulus SRC;ARG1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ARG1;ABL1 GO:0048678| response to axon injury ARG1;LYN GO:0032496| response to lipopolysaccharide BCR;ARG1 GO:0002250| adaptive immune response ARG1;LYN GO:0042493| response to drug LYN;ARG1;ABCB1;SRC 4350:[DB06616 DB14540] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1;CYP3A4;CYP2C8 common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCB1 GO:0098609| ANXA1;SRC GO:0043434| response to peptide hormone stimulus ANXA1;LYN GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP11B2;CYP11B1;CYP3A5;CYP2C8 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0070555| response to interleukin-1 SRC;ANXA1 GO:0007165| signal transduction NR3C1;LYN;MAP2K1;SRC;BCR;ANXA1 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0097267| CYP2C8 GO:0009725| response to hormone stimulus LYN;ANXA1 GO:0002376| immune system process ANXA1;SRC;HCK;LYN GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP3A5 GO:0006915| apoptotic process NR3C1;ABL1 GO:0032868| response to insulin stimulus HSD11B2;LYN GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1;ABCG2 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0009636| response to toxin LYN;SLC22A8 GO:0014070| response to organic cyclic compound LYN;ANXA1 GO:0030216| keratinocyte differentiation MAP2K1;ANXA1 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0046632| alpha-beta T cell differentiation ABL1;ANXA1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0070301| cellular response to hydrogen peroxide ABL1;ANXA1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042127| regulation of cell proliferation SRC;ANXA1;ABL1 GO:0046483| heterocycle metabolic process CYP3A4 GO:1901529| ABCB1 GO:0030073| insulin secretion CAMK2G;ANXA1 GO:0006629| lipid metabolic process CYP3A4;CYP11B2;CYP11B1 GO:0006706| steroid catabolic process CYP3A4 GO:0008360| regulation of cell shape HCK;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0045087| innate immune response LYN;SRC;HCK;ABL1;ANXA1 GO:0006082| organic acid metabolic process CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0043066| negative regulation of apoptotic process ANXA1;HCK;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0043065| positive regulation of apoptotic process ABL1;ANXA1;SRC GO:0050727| regulation of inflammatory response ANXA1;HCK;LYN GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;ABL1 GO:0055114| oxidation-reduction process CYP2C8;HSD3B1;HSD11B2;CYP3A5;CYP11B2;CYP11B1;CYP3A7;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006909| phagocytosis HCK;ABL1;ANXA1 GO:0042493| response to drug LYN;ABCB1;SRC;HSD11B2;ANXA1;ABCG2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0002250| adaptive immune response ANXA1;LYN GO:0051301| cell division NR3C1;CDK2 GO:0006954| inflammatory response LYN;ANXA1;HCK 4351:[DB06616 DB05301] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05301|LAX-101 PLD1;CASP1 common genes common pathways GO:0006915| apoptotic process ABL1;CASP1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;CASP1 GO:0050715| positive regulation of cytokine secretion CASP1;SRC GO:0010506| regulation of autophagy ABL1;CASP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;ABL1 GO:0007265| Ras protein signal transduction PLD1;CDK2 GO:0048870| cell motility PLD1;MAP2K1 GO:0032496| response to lipopolysaccharide CASP1;BCR GO:0071260| cellular response to mechanical stimulus CASP1;MAP3K2 GO:0051882| mitochondrial depolarization ABL1;CASP1 GO:0006629| lipid metabolic process PLD1;CYP3A4 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;CASP1 GO:0006935| chemotaxis PLD1;MAP2K1 GO:0071222| cellular response to lipopolysaccharide CASP1;ABL1;BCR;SRC GO:0050727| regulation of inflammatory response LYN;CASP1;HCK 4352:[DB06616 DB00557] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00557|Hydroxyzine HRH1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0043114| regulation of vascular permeability HRH1;SRC;BCR GO:0006954| inflammatory response HCK;HRH1;LYN GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction SRC;BCR;MAP2K1;HRH1;LYN GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 4353:[DB06616 DB07421] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;AR;MAP3K2;CDK2 GO:0051259| protein oligomerization CAMK2G;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;AR;HCK GO:0042327| positive regulation of phosphorylation LYN;AR GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0006810| transport ABCB1;AR GO:0007165| signal transduction AR;MAP2K1;BCR;SRC;LYN 4354:[DB06616 DB03088] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03088|Pidolic Acid VEGFA;AMY2A;IGLC1;TFF2;cycA;ADAM28;KRTAP5-2;HCRT;CCL8;AMY2B;ANG;AMY1A;AMY2A common genes common pathways GO:0010629| negative regulation of gene expression VEGFA;MAP2K1;MAP2K2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;ABL1 GO:0034332| adherens junction organization ANG;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;VEGFA;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;VEGFA GO:0050900| leukocyte migration LYN;IGLC1;SRC GO:0006816| calcium ion transport CAMK2G;CCL8 GO:0006954| inflammatory response HCK;LYN;CCL8 GO:0002250| adaptive immune response IGLC1;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;VEGFA;ABL1;SRC GO:0031954| positive regulation of protein autophosphorylation VEGFA;SRC GO:0038096| ABL1;SRC;HCK;LYN;IGLC1 GO:0051894| positive regulation of focal adhesion assembly VEGFA;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein VEGFA;LYN GO:0007498| mesoderm development VEGFA;HCK GO:0007275| multicellular organismal development ANG;CAMK2G;CDK2;VEGFA GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;VEGFA GO:0051272| positive regulation of cellular component movement LYN;VEGFA GO:0043066| negative regulation of apoptotic process HCK;SRC;VEGFA GO:0042327| positive regulation of phosphorylation ANG;LYN;VEGFA GO:0009615| response to virus CCL8;SRC GO:0006935| chemotaxis MAP2K1;CCL8 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;VEGFA GO:0002576| platelet degranulation VEGFA;LYN GO:0007399| nervous system development VEGFA;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VEGFA GO:0045087| innate immune response SRC;HCK;ABL1;IGLC1;ANG;LYN GO:0032148| activation of protein kinase B activity ANG;SRC GO:0008360| regulation of cell shape VEGFA;HCK GO:0016477| cell migration SRC;ANG GO:0038095| LYN;IGLC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;CCL8;VEGFA GO:0045785| positive regulation of cell adhesion VEGFA;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;VEGFA GO:0050853| B cell receptor signaling pathway ABL1;LYN;IGLC1 GO:0043406| positive regulation of MAP kinase activity SRC;VEGFA GO:0043547| positive regulation of GTPase activity CCL8;BCR GO:0030335| positive regulation of cell migration VEGFA;LYN GO:0010595| positive regulation of endothelial cell migration VEGFA;ABL1 GO:0071456| cellular response to hypoxia SRC;VEGFA GO:0007204| elevation of cytosolic calcium ion concentration HCRT;ABL1 GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;CCL8;LYN;CDK2;CAMK2G GO:0030154| cell differentiation HCK;VEGFA;CAMK2G;ANG GO:0002376| immune system process LYN;IGLC1;SRC;HCK GO:0009725| response to hormone stimulus ANG;LYN GO:0006887| exocytosis HCK;CCL8 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;CCL8 4355:[DB06616 DB08173] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08173|5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 4356:[DB06616 DB05509] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05509|LI-301 OPRM1;HTR1A common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;OPRM1 GO:0008283| cell proliferation HTR1A;SRC GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0007165| signal transduction LYN;HTR1A;OPRM1;MAP2K1;SRC;BCR 4357:[DB06616 DB13872] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0007420| brain development BCR;GABRA5 GO:0007165| signal transduction LYN;GABRA5;SRC;BCR;MAP2K1 GO:0006810| transport ABCB1;GABRA1;GABRG2;GABRA5;GABRA3 GO:0009791| post-embryonic development ABL1;GABRG2 4358:[DB06616 DB04741] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04741|Myxothiazol UQCRC1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;UQCRC1;CYP3A4 4359:[DB06616 DB14503] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0055085| transmembrane transport SLC34A3;ABCB1;SLC34A2;SLC20A2;SLC20A1 GO:0007165| signal transduction SLC20A1;LYN;SRC;BCR;MAP2K1 GO:0043434| response to peptide hormone stimulus SLC34A1;LYN GO:0006810| transport ABCB1;SLC20A2;SLC20A1 GO:0016032| viral reproduction LYN;SLC20A2;HCK;SRC GO:0042493| response to drug ABCB1;SRC;SLC34A1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;SLC20A1 4360:[DB06616 DB05984] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05984|RAF-265 KDR;BRAF common genes common pathways GO:0048679| regulation of axon regeneration BRAF;MAP2K1 GO:0007275| multicellular organismal development CAMK2G;CDK2;KDR GO:0018108| peptidyl-tyrosine phosphorylation LYN;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR;ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0042127| regulation of cell proliferation BRAF;SRC;ABL1 GO:0050772| positive regulation of axonogenesis MAP2K1;BRAF GO:0008360| regulation of cell shape KDR;HCK GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;BRAF;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR GO:0043066| negative regulation of apoptotic process BRAF;SRC;KDR;HCK GO:0008284| positive regulation of cell proliferation HCK;KDR;LYN;CDK2 GO:0001934| positive regulation of protein phosphorylation KDR;ABL1;LYN GO:0010629| negative regulation of gene expression KDR;MAP2K1;MAP2K2 GO:0038083| LYN;KDR;HCK;SRC;ABL1 GO:0000165| MAPKKK cascade CAMK2G;BRAF;MAP2K2;MAP2K1 GO:0016032| viral reproduction LYN;HCK;KDR;SRC GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0060324| face development MAP2K1;BRAF GO:0000186| activation of MAPKK activity MAP3K2;BRAF GO:0006468| protein phosphorylation KDR;MAP2K1;HCK;BCR;BRAF;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0030154| cell differentiation CAMK2G;HCK;KDR;BRAF GO:0030335| positive regulation of cell migration KDR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;KDR;LYN GO:0043434| response to peptide hormone stimulus BRAF;LYN GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation ABL1;KDR;MAP2K1;HCK;BCR;BRAF;MAP2K2;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0007165| signal transduction LYN;BCR;BRAF;SRC;MAP2K1 GO:1900026| ABL1;BRAF GO:0030878| thyroid gland development BRAF;MAP2K1 GO:0048538| thymus development BRAF;MAP2K1;ABL1 GO:0045580| regulation of T cell differentiation ABL1;BRAF GO:0070374| positive regulation of ERK1 and ERK2 cascade BRAF;MAP2K2;SRC;KDR;MAP2K1;ABL1 GO:0051496| positive regulation of stress fiber assembly BRAF;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis BRAF;KDR;ABL1 GO:0046632| alpha-beta T cell differentiation BRAF;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;BRAF;SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;KDR;HCK;BCR;SRC 4361:[DB06616 DB02029] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways GO:0006954| inflammatory response EPHX2;LYN;HCK GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0009636| response to toxin EPHX2;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;EPHX2 GO:0017144| drug metabolic process CYP2C8;EPHX2;CYP3A4 4362:[DB06616 DB11601] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11601|Tuberculin Purified Protein Derivative TLR2 common genes common pathways GO:0002376| immune system process LYN;TLR2;HCK;SRC GO:0070542| response to fatty acid TLR2;SRC GO:0007165| signal transduction TLR2;LYN;SRC;BCR;MAP2K1 GO:0009636| response to toxin LYN;TLR2 GO:0006915| apoptotic process ABL1;TLR2 GO:0032868| response to insulin stimulus LYN;TLR2 GO:0010628| positive regulation of gene expression TLR2;SRC;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;TLR2;MAP2K1 GO:0032496| response to lipopolysaccharide BCR;TLR2 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;TLR2;HCK GO:0045087| innate immune response TLR2;LYN;SRC;HCK;ABL1 GO:0050707| regulation of cytokine secretion LYN;TLR2 GO:0006954| inflammatory response LYN;TLR2;HCK 4363:[DB06616 DB03896] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03896|Triphosphoric acid PAPOLA common genes common pathways 4364:[DB06616 DB06190] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06190|Solabegron ADRB3 common genes common pathways GO:0007165| signal transduction ADRB3;BCR;SRC;MAP2K1;LYN 4365:[DB06616 DB06787] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007399| nervous system development CAMK2G;CHRM1;CHRM2;CHRM3 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CHRM1 GO:0009615| response to virus CHRM2;SRC GO:0007165| signal transduction CHRM1;CHRM2;LYN;CHRM3;SRC;BCR;CHRM4;MAP2K1 GO:0006464| protein modification process CHRM3;CHRM1;ABL1 GO:0008283| cell proliferation CHRM3;CHRM1;SRC;CHRM4 4366:[DB06616 DB03860] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;ESR2;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;ESR2;MAP3K2;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 4367:[DB06616 DB01228] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCB1;SCN5A GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 4368:[DB06616 DB01651] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01651|Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside APCS common genes common pathways GO:0045087| innate immune response SRC;HCK;ABL1;APCS;LYN 4369:[DB06616 DB02559] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 4370:[DB06616 DB02222] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways GO:0042493| response to drug ABCB1;SRC;LYN;PNP 4371:[DB06616 DB07111] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways GO:0014070| response to organic cyclic compound LYN;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0010033| response to organic substance PPARG;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction PPARG;LYN;SRC;BCR;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2;PPARG GO:0042493| response to drug SRC;ABCB1;PPARG;LYN GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0045087| innate immune response PPARG;LYN;ABL1;SRC;HCK GO:0007507| heart development MAP2K1;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG 4372:[DB06616 DB00707] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00707|Porfimer sodium LDLR;FCGR1A common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;FCGR1A GO:0002376| immune system process LYN;FCGR1A;SRC;HCK GO:0060333| interferon-gamma-mediated signaling pathway FCGR1A;HCK;CAMK2G GO:0008202| steroid metabolic process CYP3A4;LDLR;CYP2C8 GO:0010628| positive regulation of gene expression LDLR;MAP2K1;SRC GO:0045087| innate immune response LYN;SRC;HCK;ABL1;FCGR1A GO:0006629| lipid metabolic process LDLR;CYP3A4 GO:0006897| endocytosis ABL1;LDLR GO:0071398| cellular response to fatty acid SRC;LDLR GO:0038096| FCGR1A;ABL1;HCK;SRC;LYN GO:0016032| viral reproduction LDLR;LYN;SRC;HCK GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;LDLR 4373:[DB06616 DB06241] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06241|Clenoliximab CD4 common genes common pathways GO:0007155| cell adhesion CD4;ABL1;SRC;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD4;ABL1 GO:0002250| adaptive immune response LYN;CD4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;CD4 GO:0051924| regulation of calcium ion transport CD4;CAMK2G GO:0016032| viral reproduction HCK;SRC;CD4;LYN GO:0001934| positive regulation of protein phosphorylation CD4;LYN;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CD4;MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 GO:0007165| signal transduction LYN;CD4;MAP2K1;SRC;BCR GO:0002376| immune system process HCK;SRC;CD4;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;CD4;HCK GO:0031295| T cell costimulation LYN;CD4;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade CD4;ABL1;SRC;MAP2K2;MAP2K1 GO:0050690| regulation of defense response to virus by virus CD4;HCK 4374:[DB06616 DB03135] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03135|[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid TPI1 common genes common pathways GO:0007275| multicellular organismal development TPI1;CDK2;CAMK2G 4375:[DB06616 DB02126] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways GO:0042542| response to hydrogen peroxide SRC;HBB;HBA1 GO:0007596| blood coagulation HBB;LYN 4376:[DB06616 DB01252] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0032868| response to insulin stimulus ABCC8;LYN GO:0055085| transmembrane transport ABCB1;ABCC8 GO:0014070| response to organic cyclic compound PPARG;LYN GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT2B7 GO:0007165| signal transduction ABCC8;LYN;PPARG;MAP2K1;BCR;SRC GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A3 GO:0006813| potassium ion transport CDK2;ABCC8 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0042493| response to drug PPARG;LYN;ABCC8;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;PPARG;MAP3K2 GO:0032496| response to lipopolysaccharide BCR;ABCC8 GO:0007507| heart development PPARG;MAP2K1 GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process CYP3A4;PPARG;UGT2B7 GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG 4377:[DB06616 DB06262] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0055114| oxidation-reduction process CYP3A4;PAH;CYP2C8 GO:0042493| response to drug ABCB1;SRC;ADRA1A;LYN;SLC6A2 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0035556| intracellular signal transduction ADRA1A;SRC;BCR;ADRA1B;LYN;CAMK2G GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;ADRA1D;LYN;CDK2 GO:0007275| multicellular organismal development ADRA1D;CDK2;CAMK2G;ADRA1B GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;ADRA2B GO:0055085| transmembrane transport SLC6A2;SLC16A10;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;ADRA1A;SRC;MAP2K1 GO:0009636| response to toxin DDC;LYN GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0007165| signal transduction ADRA2C;ADRA2B;LYN;ADRB2;ADRA1D;ADRA2A;ADRA1B;ADRB3;SRC;ADRA1A;ADRB1;BCR;MAP2K1 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0045453| bone resorption SRC;ADRB2 GO:0006810| transport ABCB1;SLC6A2 GO:0030168| platelet activation ADRA2C;ADRA2B;LYN;SRC;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ABL1;ADRA1B GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0030335| positive regulation of cell migration ADRA2A;LYN 4378:[DB06616 DB08214] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;BCR;SRC;ABL1 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 4379:[DB06616 DB00260] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00260|Cycloserine ddlA;DDC;SLC36A2 common genes common pathways GO:0009636| response to toxin LYN;DDC 4380:[DB06616 DB02779] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways GO:0060020| Bergmann glial cell differentiation ABL1;PTPN11;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;PTPN11 GO:0050900| leukocyte migration LYN;SRC;PTPN11 GO:0048011| nerve growth factor receptor signaling pathway SRC;PTPN11 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;PTPN11;SRC GO:0007507| heart development PTPN11;MAP2K1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTPN11 GO:0006629| lipid metabolic process CYP3A4;PTPN11 GO:0021697| cerebellar cortex formation MAP2K1;PTPN11 GO:0045931| positive regulation of mitotic cell cycle ABL1;PTPN11 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC;PTPN11 GO:0007411| axon guidance SRC;PTPN11 GO:0048013| ephrin receptor signaling pathway PTPN11;SRC;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;PTPN11;MAP2K1 GO:0033628| regulation of cell adhesion mediated by integrin PTPN11;LYN GO:0000187| activation of MAPK activity MAP3K2;PTPN11;MAP2K1;MAP2K2 GO:0006470| protein dephosphorylation PTPN11;CAMK2G GO:0007420| brain development BCR;PTPN11 GO:0007229| integrin-mediated signaling pathway SRC;HCK;PTPN11;ABL1 GO:0030168| platelet activation LYN;PTPN11;SRC GO:0031295| T cell costimulation SRC;PTPN11;LYN 4381:[DB06616 DB08495] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08495|4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0007596| blood coagulation LYN;F10 GO:0030335| positive regulation of cell migration F10;LYN 4382:[DB06616 DB05303] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;SRC;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0050727| regulation of inflammatory response HCK;IL1R1;TNF;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;TNF GO:0071222| cellular response to lipopolysaccharide TNF;ABL1;BCR;SRC GO:0009615| response to virus TNF;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;TNF;LYN GO:0050900| leukocyte migration TNF;LYN;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;TNF;LYN GO:0010629| negative regulation of gene expression TNF;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;TNF;MAP2K2;SRC;MAP2K1 GO:0019221| cytokine-mediated signaling pathway HCK;IL1R1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0071803| positive regulation of podosome assembly SRC;TNF GO:0006954| inflammatory response HCK;LYN;TNF GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0007165| signal transduction IL1R1;MAP2K1;SRC;BCR;LYN GO:0051222| positive regulation of protein transport SRC;TNF GO:0070555| response to interleukin-1 IL1R1;SRC GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ABL1;MAP2K1;SRC;MAP2K2 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TNF;MAP3K2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNF GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0010033| response to organic substance CDK2;TNF GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0045892| negative regulation of transcription, DNA-dependent TNF;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;TNF 4383:[DB06616 DB07171] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways GO:0007507| heart development ECE1;MAP2K1 4384:[DB06616 DB00002] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0050766| positive regulation of phagocytosis BCR;FCGR2B GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;BCR;SRC;EGFR;HCK GO:0034614| cellular response to reactive oxygen species EGFR;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;EGFR;MAP2K2;SRC;ABL1 GO:0008283| cell proliferation SRC;EGFR GO:0014070| response to organic cyclic compound EGFR;LYN GO:0007165| signal transduction LYN;FCGR2B;FCGR2C;FCGR1A;MAP2K1;EGFR;BCR;SRC GO:0070372| regulation of ERK1 and ERK2 cascade LYN;EGFR GO:0060333| interferon-gamma-mediated signaling pathway FCGR1A;HCK;CAMK2G GO:0002376| immune system process SRC;HCK;C1QA;FCGR2A;FCGR1A;C1QB;C1R;C1S;C1QC;LYN GO:0006979| response to oxidative stress ABL1;EGFR GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;EGFR;HCK;MAP2K1;ABL1 GO:1903800| MAP2K2;EGFR;MAP2K1 GO:0030889| negative regulation of B cell proliferation LYN;FCGR2B GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:0016310| phosphorylation HCK;EGFR;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EGFR;HCK;LYN GO:0098609| SRC;EGFR GO:0030335| positive regulation of cell migration EGFR;LYN GO:0038128| EGFR;SRC GO:0038096| ABL1;FCGR1A;FCGR2A;SRC;HCK;FCGR2B;LYN;FCGR3A GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC GO:0000165| MAPKKK cascade MAP2K1;EGFR;MAP2K2;CAMK2G GO:0006954| inflammatory response HCK;FCGR2B;LYN GO:0016032| viral reproduction HCK;SRC;LYN;FCGR2B GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;EGFR GO:0038083| SRC;EGFR;HCK;ABL1;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;EGFR;MAP2K1;SRC;MAP2K2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;EGFR;ABL1 GO:1901216| ABL1;FCGR2B GO:0045087| innate immune response ABL1;FCGR1A;SRC;HCK;C1QA;C1S;C1QC;LYN;C1QB;C1R GO:0050777| negative regulation of immune response FCGR2B;LYN GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0008284| positive regulation of cell proliferation HCK;EGFR;CDK2;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;EGFR GO:0042327| positive regulation of phosphorylation LYN;EGFR GO:0035556| intracellular signal transduction SRC;BCR;EGFR;CAMK2G;LYN GO:2000145| regulation of cell motility EGFR;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;EGFR;MAP2K1;LYN GO:0007275| multicellular organismal development EGFR;CDK2;CAMK2G GO:0042127| regulation of cell proliferation EGFR;SRC;ABL1 4385:[DB06616 DB09146] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09146|Iron saccharate HBA1;TF common genes common pathways GO:0042542| response to hydrogen peroxide HBA1;SRC GO:0002576| platelet degranulation TF;LYN 4386:[DB06616 DB09449] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;SLC20A1 GO:0042493| response to drug SLC34A1;ABCB1;SRC;LYN GO:0016032| viral reproduction SLC20A2;SRC;HCK;LYN GO:0006810| transport SLC20A1;SLC20A2;ABCB1 GO:0043434| response to peptide hormone stimulus LYN;SLC34A1 GO:0007165| signal transduction SLC20A1;LYN;BCR;SRC;MAP2K1 GO:0055085| transmembrane transport SLC20A1;SLC20A2;ABCB1;SLC34A3;SLC34A2 4387:[DB06616 DB05428] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05428|motexafin gadolinium TXNRD1;TXNRD2;RRM2 common genes common pathways GO:0034599| cellular response to oxidative stress TXNRD2;ABL1;TXNRD1 GO:0006260| DNA replication CDK2;RRM2 GO:0055114| oxidation-reduction process TXNRD1;CYP2C8;RRM2;TXNRD2;CYP3A4 GO:0007165| signal transduction MAP2K1;TXNRD1;BCR;SRC;LYN GO:0008283| cell proliferation SRC;TXNRD1 4388:[DB06616 DB00083] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways GO:0007275| multicellular organismal development CDK2;RHOB;CAMK2G GO:0043065| positive regulation of apoptotic process RHOB;SRC;ABL1 GO:0007155| cell adhesion ABL1;SRC;HCK;RHOB GO:0010595| positive regulation of endothelial cell migration RHOB;ABL1 GO:0030168| platelet activation LYN;RHOB;SRC GO:0030154| cell differentiation HCK;CAMK2G;RHOB GO:0051056| regulation of small GTPase mediated signal transduction BCR;RHOB GO:0006915| apoptotic process RHOB;ABL1 GO:0030336| negative regulation of cell migration BCR;RHOB GO:0070301| cellular response to hydrogen peroxide ABL1;RHOB 4389:[DB06616 DB02201] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 4390:[DB06616 DB13269] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0007155| cell adhesion SCN1B;SRC;HCK;ABL1 GO:0007399| nervous system development SCN8A;CAMK2G;SCN3B;SCN2B;SCN2A GO:0042493| response to drug SRC;ABCB1;SCN11A;LYN GO:0010976| positive regulation of neuron projection development LYN;SCN1B GO:0006954| inflammatory response HCK;LYN;SCN9A GO:0009636| response to toxin LYN;SCN9A GO:0055085| transmembrane transport ABCB1;SCN4A;SCN7A;SCN5A;SCN2A;SCN3A;SCN1A;SCN10A;SCN9A;SCN11A;SCN8A GO:0009791| post-embryonic development ABL1;SCN9A GO:0007411| axon guidance SCN1B;SRC 4391:[DB06616 DB07146] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC GO:0016032| viral reproduction SRC;LCK;HCK;LYN GO:0050900| leukocyte migration LYN;SRC;LCK GO:0042493| response to drug LYN;SRC;ABCB1;LCK GO:0038083| SRC;LCK;HCK;ABL1;LYN GO:0045087| innate immune response ABL1;LCK;HCK;SRC;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;LCK;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN GO:0042127| regulation of cell proliferation ABL1;LCK;SRC GO:0050853| B cell receptor signaling pathway LCK;ABL1;LYN GO:0006470| protein dephosphorylation CAMK2G;LCK GO:0016477| cell migration LCK;SRC GO:0050690| regulation of defense response to virus by virus LCK;HCK GO:0030097| hemopoiesis LCK;LYN GO:0030168| platelet activation LYN;SRC;LCK GO:0006468| protein phosphorylation ABL1;HCK;LCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LCK;HCK;LYN GO:0031295| T cell costimulation LYN;SRC;LCK GO:0016310| phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;MAP2K1;LCK;HCK;MAP2K2;BCR;SRC 4392:[DB06616 DB07975] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process ABL1;DHODH;SRC GO:0042493| response to drug ABCB1;SRC;DHODH;LYN GO:0055114| oxidation-reduction process DHODH;CYP2C8;CYP3A4 GO:0014070| response to organic cyclic compound LYN;DHODH 4393:[DB06616 DB04739] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04739|4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE SRC common genes SRC common pathways GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0098609| SRC GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0031295| T cell costimulation SRC;LYN GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0071456| cellular response to hypoxia SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0006468| protein phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0048477| oogenesis SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;SRC;BCR;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0007411| axon guidance SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;BCR GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0033625| positive regulation of integrin activation SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045087| innate immune response LYN;ABL1;HCK;SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0045056| transcytosis SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;LYN GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0086098| SRC GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0016032| viral reproduction LYN;HCK;SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:0038128| SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| SRC;HCK;ABL1;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0038083| ABL1;HCK;SRC;LYN GO:0042493| response to drug ABCB1;SRC;LYN GO:0034332| adherens junction organization SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0050900| leukocyte migration SRC;LYN 4394:[DB06616 DB13775] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13775|Tertatolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 4395:[DB06616 DB08213] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways GO:0010033| response to organic substance CASP3;CDK2 GO:0006915| apoptotic process CASP3;ABL1 GO:0043200| response to amino acid stimulus CASP3;LYN GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0030216| keratinocyte differentiation MAP2K1;CASP3 GO:0030182| neuron differentiation ABL1;CASP3;MAP2K1 GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0001782| B cell homeostasis LYN;CASP3 GO:0030218| erythrocyte differentiation CASP3;LYN GO:0048011| nerve growth factor receptor signaling pathway CASP3;SRC GO:0042493| response to drug LYN;CASP3;SRC;ABCB1 GO:0006974| response to DNA damage stimulus CASP3;ABL1;CDK2;LYN GO:0007507| heart development CASP3;MAP2K1 GO:0035556| intracellular signal transduction CASP3;BCR;SRC;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process HCK;CASP3;SRC GO:0043065| positive regulation of apoptotic process SRC;CASP3;ABL1 GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0032496| response to lipopolysaccharide BCR;CASP3 4396:[DB06616 DB02034] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02034|Tridolgosir MAN2A1 common genes common pathways 4397:[DB06616 DB03693] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways GO:0008360| regulation of cell shape CSNK1G2;HCK GO:0006897| endocytosis CSNK1G2;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CSNK1G2;CDK2 GO:0046777| protein autophosphorylation CSNK1G2;LYN;CAMK2G;HCK;SRC;BCR;ABL1 GO:0007165| signal transduction LYN;CSNK1G2;BCR;SRC;MAP2K1 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;CSNK1G2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;CSNK1G2;LYN;CDK2;CAMK2G 4398:[DB06616 DB05041] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05041|RP101 UPP1;UPP2 common genes common pathways 4399:[DB06616 DB02624] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02624|Homoserine Lactone SLC9A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus SLC9A1;MAP3K2 GO:0043065| positive regulation of apoptotic process SLC9A1;ABL1;SRC GO:0043066| negative regulation of apoptotic process SLC9A1;HCK;SRC GO:0051259| protein oligomerization CAMK2G;SLC9A1 GO:0010447| response to acidity SLC9A1;SRC GO:0055085| transmembrane transport ABCB1;SLC9A1 GO:0014070| response to organic cyclic compound LYN;SLC9A1 GO:0016477| cell migration SLC9A1;SRC GO:1902533| SRC;SLC9A1 GO:0032869| cellular response to insulin stimulus SLC9A1;SRC GO:0071456| cellular response to hypoxia SRC;SLC9A1 GO:0030154| cell differentiation HCK;SLC9A1;CAMK2G 4400:[DB06616 DB08595] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08595|4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction LYN;ESR1;MAP2K1;SRC;BCR GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;MAP2K2;SRC;MAP2K1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;ESR1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0060065| uterus development ESR1;SRC 4401:[DB06616 DB11348] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0065009| regulation of molecular function NRXN1;CAMK2G GO:0051281| positive regulation of release of sequestered calcium ion into cytosol SRI;CASQ1;ABL1 GO:0007165| signal transduction LYN;SLC20A1;SRI;S100A6;SPARC;CASR;MAP2K1;BCR;CACNA1I;SRC GO:0006887| exocytosis CADPS2;HCK;CADPS GO:0051222| positive regulation of protein transport CHP1;SRC GO:0010907| positive regulation of glucose metabolic process RGN;SRC GO:0006813| potassium ion transport CDK2;CHP1 GO:1900026| CALR;CIB1;ABL1 GO:0006810| transport CACNB3;SLC20A1;CACNA1E;SRI;SLC20A2;CACNB1;CACNB4;CACNA1I;ABCB1 GO:0030154| cell differentiation TPT1;CAMK2G;CALR3;CATSPER1;CIB1;HCK GO:0007204| elevation of cytosolic calcium ion concentration CIB2;CACNA1C;SLC8A1;CACNA1A;ABL1 GO:0071456| cellular response to hypoxia CASR;S100B;SRC;SLC8A1 GO:0043547| positive regulation of GTPase activity BCR;RGN GO:0030335| positive regulation of cell migration LYN;CIB1 GO:0043434| response to peptide hormone stimulus SLC34A1;SPARC;LYN GO:0034605| cellular response to heat LYN;PDCD6 GO:0010595| positive regulation of endothelial cell migration CALR;ABL1;SPARC;PDCD6 GO:0007417| central nervous system development S100B;SRC;LYN GO:0010033| response to organic substance CDK2;CASQ1;CALR GO:0008285| negative regulation of cell proliferation CIB1;MAP2K1;LYN GO:0007049| cell cycle SRC;CIB1;CDK2 GO:0050766| positive regulation of phagocytosis CALR;BCR GO:0045892| negative regulation of transcription, DNA-dependent SRC;CALR GO:0007411| axon guidance SRC;NRXN1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;CASR;CALR GO:0034614| cellular response to reactive oxygen species SLC8A1;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity CALM2;CALM3;CALM1;MAP2K1;CIB1;MAP2K2;SRC GO:0006915| apoptotic process PDCD6;CIB1;ABL1;CASR GO:0071901| negative regulation of protein serine/threonine kinase activity CIB1;ABL1 GO:0055085| transmembrane transport TRPV6;SLC20A1;CACNA1E;RYR3;CACNA1H;CACNA1G;CACNA1S;CATSPER1;TRPV5;SLC20A2;CALM1;CACNA1F;SLC34A2;CACNA1C;RYR2;RYR1;SLC34A3;CACNA1A;CACNA1D;SLC8A1;CACNA1I;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;CIB1 GO:0014070| response to organic cyclic compound CASR;LYN GO:0050663| cytokine secretion LYN;S100A13 GO:0008283| cell proliferation S100B;SRC GO:0038095| LYN;CALM1 GO:0006974| response to DNA damage stimulus ABL1;CIB1;CDK2;LYN GO:0007507| heart development SPARC;CACNA1C;MAP2K1;SRI GO:0007155| cell adhesion ABL1;CIB1;HCK;SRC;NRXN1 GO:0045087| innate immune response S100B;HCK;SRC;ABL1;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CALR GO:0008360| regulation of cell shape S100A13;S100B;HCK GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;CALR;TPT1;MAP3K2 GO:0035556| intracellular signal transduction BCR;CAPS;SRC;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process SRC;CIB1;HCK;ALB;RGN;TPT1 GO:0043065| positive regulation of apoptotic process SRC;S100B;ABL1 GO:0002576| platelet degranulation LYN;ALB;CALM1;SPARC GO:0042542| response to hydrogen peroxide SRC;SLC8A1 GO:0009615| response to virus SRC;TPT1 GO:0008284| positive regulation of cell proliferation CALR;CDK2;LYN;CASR;S100A13;S100B;CIB1;HCK GO:0007275| multicellular organismal development RYR2;RYR1;CDK2;CAMK2G;CATSPER1 GO:0051259| protein oligomerization CAMK2G;CHP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;S100B;S100A13;ABL1 GO:0001933| negative regulation of protein phosphorylation RGN;LYN;CHP1;CIB1 GO:0042127| regulation of cell proliferation CIB1;SRC;SPARC;ABL1 GO:0032496| response to lipopolysaccharide SPARC;BCR GO:0000165| MAPKKK cascade CALM1;MAP2K2;MAP2K1;CAMK2G GO:0031954| positive regulation of protein autophosphorylation CALM1;CALM3;SRC;CALM2 GO:0051924| regulation of calcium ion transport CASR;SLC8A1;CAMK2G;SRI GO:0051602| response to electrical stimulus S100A13;SRC GO:0006816| calcium ion transport CACNA1F;CACNA1C;RYR1;RYR2;CACNB4;CACNA1A;SLC8A1;CACNA1I;CACNA1D;PKD1L3;CACNB1;CASR;CACNA1E;RYR3;SRI;CACNA1H;PKD2L1;CACNA1G;TRPV5;CATSPER1;CACNA1S;TPT1;CACNB3;TRPV6;CAMK2G;CACNB2 GO:0016032| viral reproduction LYN;HCK;SRC;SLC20A2 GO:0090398| cellular senescence MAP2K1;CALR GO:0051301| cell division CDK2;CIB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;CIB1 GO:0001934| positive regulation of protein phosphorylation LYN;CIB1;ABL1 GO:0050885| neuromuscular process controlling balance NRXN1;BCR;ABL1 GO:0042493| response to drug SLC34A1;SRC;SLC8A1;ABCB1;LYN;CALR GO:0006355| regulation of transcription, DNA-dependent CALR;ABL1 4402:[DB06616 DB08230] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08230|5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE PIM1 common genes common pathways GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;PIM1 GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;PIM1;MAP3K2;CAMK2G;LYN;CDK2 GO:0006915| apoptotic process PIM1;ABL1 GO:0008283| cell proliferation SRC;PIM1 GO:0007049| cell cycle PIM1;CDK2;SRC GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN;PIM1 GO:0007275| multicellular organismal development PIM1;CDK2;CAMK2G GO:0043066| negative regulation of apoptotic process SRC;HCK;PIM1 GO:0007346| regulation of mitotic cell cycle PIM1;MAP3K2;MAP2K2;MAP2K1 4403:[DB06616 DB07644] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07644|5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine DCPS common genes common pathways 4404:[DB06616 DB12191] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12191|Obatoclax BCL2 common genes common pathways GO:0042100| B cell proliferation BCL2;ABL1 GO:0018107| peptidyl-threonine phosphorylation BCL2;CAMK2G;MAP2K1 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0006915| apoptotic process ABL1;BCL2 GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;BCL2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;BCL2 GO:0008283| cell proliferation BCL2;SRC GO:0006470| protein dephosphorylation CAMK2G;BCL2 GO:0009636| response to toxin LYN;BCL2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCL2 GO:0014911| positive regulation of smooth muscle cell migration SRC;BCL2 GO:0030336| negative regulation of cell migration BCL2;BCR GO:0009791| post-embryonic development BCL2;ABL1 GO:0050853| B cell receptor signaling pathway ABL1;LYN;BCL2 GO:0071456| cellular response to hypoxia BCL2;SRC GO:0045930| negative regulation of mitotic cell cycle BCL2;ABL1 GO:0098609| SRC;BCL2 GO:0003014| renal system process BCL2;BCR GO:0030097| hemopoiesis LYN;BCL2 GO:0048536| spleen development BCL2;ABL1 GO:0048538| thymus development BCL2;ABL1;MAP2K1 GO:0006979| response to oxidative stress ABL1;BCL2 GO:0042493| response to drug LYN;BCL2;ABCB1;SRC GO:0051902| negative regulation of mitochondrial depolarization SRC;BCL2 GO:0010506| regulation of autophagy BCL2;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2 GO:0051924| regulation of calcium ion transport BCL2;CAMK2G GO:0001782| B cell homeostasis LYN;BCL2 GO:2000811| negative regulation of anoikis SRC;BCL2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;BCL2 GO:0006974| response to DNA damage stimulus BCL2;LYN;CDK2;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;BCL2;HCK GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;BCL2 GO:0042542| response to hydrogen peroxide BCL2;SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1;BCL2 GO:0043066| negative regulation of apoptotic process SRC;HCK;BCL2 4405:[DB06616 DB04352] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 4406:[DB06616 DB03626] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03626|5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0006979| response to oxidative stress ABL1;NQO1 GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1 GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0009636| response to toxin LYN;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;SRC;HCK GO:0006805| xenobiotic metabolic process CYP3A4;NQO1;CYP2C8 GO:0051602| response to electrical stimulus NQO1;SRC GO:0055114| oxidation-reduction process CYP2C8;NQO1;CYP3A4 4407:[DB06616 DB03727] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03727|Coproporphyrin I UROD common genes common pathways 4408:[DB06616 DB00409] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00409|Remoxipride DRD2;DRD4;DRD3;HTR2A;SIGMAR1;CYP2D6 common genes common pathways GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0009636| response to toxin DRD2;LYN GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;DRD4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;ABL1;DRD2;SRC;MAP2K2;MAP2K1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0030900| forebrain development DRD2;SRC GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction HTR2A;LYN;DRD3;DRD4;MAP2K1;BCR;DRD2;SRC GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0016032| viral reproduction HCK;SRC;HTR2A;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;HTR2A;LYN GO:0042493| response to drug DRD3;HTR2A;LYN;ABCB1;DRD2;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0035556| intracellular signal transduction CAMK2G;LYN;DRD2;SRC;BCR GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HTR2A;LYN;CDK2;DRD3;HCK GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0007399| nervous system development CAMK2G;SIGMAR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DRD3 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0048678| response to axon injury DRD2;LYN GO:0042737| drug catabolic process CYP2D6;CYP3A4 4409:[DB06616 DB08807] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0008283| cell proliferation SRC;HTR1A GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K2;SRC;MAP2K1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0045453| bone resorption SRC;ADRB2 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction LYN;ADRB2;HTR1A;ADRB3;MAP2K1;SRC;HTR1B;ADRB1;BCR GO:0042493| response to drug ABCB1;HTR1B;SRC;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR1A GO:0006629| lipid metabolic process CYP2D6;CYP3A4 4410:[DB06616 DB08406] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 4411:[DB06616 DB00578] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0006629| lipid metabolic process CYP3A4;PLA2G4A GO:0042127| regulation of cell proliferation ABL1;SRC;PLA2G4A 4412:[DB06616 DB07708] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07708|3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction BCR;SRC;MAP2K1;ESR1;LYN GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;ESR1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;SRC;MAP2K2;MAP2K1 GO:0008209| androgen metabolic process CYP3A4;ESR1 4413:[DB06616 DB05483] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05483|PCL-016 UBR4;ZFY common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;ZFY GO:0048872| homeostasis of number of cells BCR;ZFY GO:0016032| viral reproduction SRC;HCK;UBR4;LYN GO:0007275| multicellular organismal development CDK2;CAMK2G;ZFY GO:0009791| post-embryonic development ABL1;ZFY 4414:[DB06616 DB08461] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction AR;SRC;BCR;MAP2K1;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;SRC;MAP2K2;AR GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0051259| protein oligomerization AR;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;AR;HCK 4415:[DB06616 DB08751] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways GO:0043547| positive regulation of GTPase activity BCR;HRAS GO:0030335| positive regulation of cell migration HRAS;LYN GO:0007165| signal transduction LYN;HRAS;MAP2K1;BCR;SRC GO:0007050| cell cycle arrest ABL1;MAP2K1;HRAS GO:0038095| LYN;HRAS GO:0008283| cell proliferation HRAS;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;HRAS GO:0006915| apoptotic process ABL1;HRAS GO:0010628| positive regulation of gene expression HRAS;SRC;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;HRAS GO:0048013| ephrin receptor signaling pathway LYN;HRAS;SRC GO:0007411| axon guidance HRAS;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;HRAS GO:0007265| Ras protein signal transduction CDK2;HRAS GO:0002223| stimulatory C-type lectin receptor signaling pathway HRAS;LYN;SRC GO:0006935| chemotaxis MAP2K1;HRAS GO:0008284| positive regulation of cell proliferation HCK;HRAS;CDK2;LYN GO:0006897| endocytosis HRAS;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;HRAS GO:0007173| epidermal growth factor receptor signaling pathway HRAS;SRC;ABL1 GO:0050900| leukocyte migration SRC;HRAS;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;HRAS GO:2000251| positive regulation of actin cytoskeleton reorganization HRAS;HCK;ABL1 GO:0090398| cellular senescence HRAS;MAP2K1 GO:0038128| SRC;HRAS GO:0000165| MAPKKK cascade HRAS;CAMK2G;MAP2K2;MAP2K1 4416:[DB06616 DB01153] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01153|Sertaconazole CYP51A1 common genes common pathways GO:0055114| oxidation-reduction process CYP51A1;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP51A1 GO:0008202| steroid metabolic process CYP3A4;CYP51A1;CYP2C8 4417:[DB06616 DB07172] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0043065| positive regulation of apoptotic process PPARG;SRC;ABL1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response ABL1;SRC;HCK;PPARG;LYN GO:0007507| heart development MAP2K1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;PPARG;MAP2K1;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0042493| response to drug SRC;ABCB1;LYN;PPARG GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PPARG GO:0014070| response to organic cyclic compound PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0010033| response to organic substance PPARG;CDK2 4418:[DB06616 DB09502] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;SLC2A1 GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;HK1;SRC;MAP2K1;HCK;ABL1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0071456| cellular response to hypoxia SLC2A4;SRC GO:0032869| cellular response to insulin stimulus SLC2A4;SRC GO:0032868| response to insulin stimulus LYN;SLC2A1 GO:0055085| transmembrane transport SLC2A12;SLC2A9;SLC2A4;SLC2A3;SLC2A8;SLC2A1;SLC2A7;SLC2A5;SLC2A11;ABCB1;SLC2A10;SLC2A6;SLC2A2 4419:[DB06616 DB01070] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01070|Dihydrotachysterol VDR common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;CDK2 GO:0006355| regulation of transcription, DNA-dependent VDR;ABL1 GO:0006816| calcium ion transport CAMK2G;VDR GO:0007165| signal transduction LYN;VDR;MAP2K1;BCR;SRC GO:0010628| positive regulation of gene expression MAP2K1;VDR;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;VDR GO:0008285| negative regulation of cell proliferation VDR;MAP2K1;LYN 4420:[DB06616 DB04683] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;NR5A1;CDK2;MAP2K1;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent NR5A1;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;NR5A1 GO:0030154| cell differentiation CAMK2G;NR5A1;HCK 4421:[DB06616 DB05505] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05505|NM-702 TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;TBXAS1;CYP3A4 GO:0006629| lipid metabolic process TBXAS1;CYP3A4 4422:[DB06616 DB02763] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways GO:0007050| cell cycle arrest ABL1;IL12B;MAP2K1 GO:0010033| response to organic substance CDK2;IL12B GO:0016477| cell migration IL12B;SRC GO:0008283| cell proliferation SRC;IL12B GO:0045785| positive regulation of cell adhesion IL12B;SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;IL12B;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL12B 4423:[DB06616 DB08847] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08847|Hydroxyproline SLC36A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC36A1 4424:[DB06616 DB02383] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 GO:0055114| oxidation-reduction process CYP2C8;AKR1A1;CYP3A4;AKR1B1;AKR1B10 GO:0008202| steroid metabolic process CYP2C8;AKR1B10;CYP3A4 GO:0010033| response to organic substance CDK2;AKR1B1 4425:[DB06616 DB11607] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11607|Efmoroctocog alfa VWF common genes common pathways GO:0002576| platelet degranulation LYN;VWF GO:0007155| cell adhesion HCK;SRC;ABL1;VWF GO:0030168| platelet activation SRC;VWF;LYN GO:0007596| blood coagulation VWF;LYN 4426:[DB06616 DB00152] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A5;SLC22A1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A5;SLC22A1 GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;TPK1;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0042738| exogenous drug catabolic process CYP2C8;CYP4B1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP4B1;CYP2C8 4427:[DB06616 DB04964] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04964|Oregovomab MUC16 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC;MUC16 GO:0007155| cell adhesion ABL1;SRC;MUC16;HCK 4428:[DB06616 DB05476] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05476|WX-UK1 PLAUR common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;PLAUR;HCK GO:0006935| chemotaxis MAP2K1;PLAUR GO:2001243| negative regulation of intrinsic apoptotic signaling pathway PLAUR;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;PLAUR;LYN GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;PLAUR GO:0006928| cellular component movement MAP2K1;PLAUR GO:0007596| blood coagulation LYN;PLAUR 4429:[DB06616 DB04727] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04727|N-(4-{4-AMINO-6-[4-(METHYLOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-5-YL}PHENYL)-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA KDR common genes common pathways GO:0046777| protein autophosphorylation ABL1;BCR;SRC;KDR;HCK;CAMK2G;LYN GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;KDR;MAP2K1;SRC;MAP2K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;KDR;HCK GO:0030335| positive regulation of cell migration KDR;LYN GO:0016310| phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0030154| cell differentiation HCK;KDR;CAMK2G GO:0016032| viral reproduction LYN;SRC;KDR;HCK GO:0070371| ERK1 and ERK2 cascade MAP2K2;KDR;MAP2K1 GO:0010629| negative regulation of gene expression KDR;MAP2K1;MAP2K2 GO:0038083| LYN;HCK;KDR;SRC;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;KDR;LYN GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process KDR;HCK;SRC GO:0008284| positive regulation of cell proliferation KDR;HCK;LYN;CDK2 GO:0008360| regulation of cell shape KDR;HCK GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation HCK;KDR;MAP2K1;SRC;BCR;MAP2K2;ABL1;LYN GO:0007275| multicellular organismal development KDR;CDK2;CAMK2G 4430:[DB06616 DB00097] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;FSHR;SRC;MAP2K1 GO:0001545| primary ovarian follicle growth SRC;FSHR;LHCGR GO:0007165| signal transduction LHCGR;LYN;BCR;FSHR;SRC;MAP2K1 4431:[DB06616 DB03971] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03971|Acarbose Derived Hexasaccharide AMY2A;AMY2A common genes common pathways 4432:[DB06616 DB00210] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;RARA;MAP2K1;RARB;LYN;PTGS2 GO:0010033| response to organic substance CDK2;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;RARA GO:0010628| positive regulation of gene expression RARG;MAP2K1;RARA;SRC GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0007165| signal transduction LYN;RARA;MAP2K1;RARB;BCR;SRC GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;RARA;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0001843| neural tube closure RARG;ABL1;RARA GO:0034605| cellular response to heat LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0060324| face development MAP2K1;RARA;RARG GO:0006954| inflammatory response HCK;PTGS2;LYN GO:0016032| viral reproduction HCK;SRC;LYN;RXRA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0042493| response to drug ABCB1;SRC;PTGS2;LYN GO:0010629| negative regulation of gene expression MAP2K1;RARA;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent RXRB;RXRA;RARG;RXRG;ABL1;RARA;RARB GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CDK2;MAP3K2;RARA;MAP2K1;SRC;MAP2K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RXRA;RARG;RARA;RARB GO:0007507| heart development MAP2K1;RXRA GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;MAP2K1;RARA GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0043065| positive regulation of apoptotic process RARG;ABL1;RARB;SRC;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;RARA;HCK;RARB;CDK2;LYN;PTGS2 GO:0071222| cellular response to lipopolysaccharide RARA;BCR;SRC;ABL1 GO:0071300| cellular response to retinoic acid LYN;RARA;RARG GO:0043066| negative regulation of apoptotic process RARA;RARB;HCK;SRC;RARG;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR 4433:[DB06616 DB07848] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07848|5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide F10 common genes common pathways GO:0030335| positive regulation of cell migration F10;LYN GO:0007596| blood coagulation F10;LYN GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC 4434:[DB06616 DB05421] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05421|CP-122721 TACR1 common genes common pathways GO:0009725| response to hormone stimulus LYN;TACR1 GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;TACR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TACR1 GO:0014070| response to organic cyclic compound TACR1;LYN GO:0051496| positive regulation of stress fiber assembly TACR1;ABL1 GO:0010634| positive regulation of epithelial cell migration SRC;TACR1 GO:0051602| response to electrical stimulus SRC;TACR1 GO:0006954| inflammatory response LYN;TACR1;HCK 4435:[DB06616 DB01155] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;LYN;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 4436:[DB06616 DB01800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01800|N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium ARSA common genes common pathways 4437:[DB06616 DB06921] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 4438:[DB06616 DB05431] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05431|MLN-977 ALOX5 common genes common pathways GO:0006954| inflammatory response LYN;ALOX5;HCK GO:0055114| oxidation-reduction process CYP3A4;ALOX5;CYP2C8 4439:[DB06616 DB02998] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0006810| transport AR;ABCB1 GO:0050847| progesterone receptor signaling pathway SRC;PGR GO:0007165| signal transduction LYN;MAP2K1;BCR;PGR;SRC;NR3C2;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;SRC GO:0051259| protein oligomerization CAMK2G;AR GO:0042327| positive regulation of phosphorylation LYN;AR GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;AR GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;NCOA2;CDK2 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;AR;MAP2K1;MAP2K2;SRC GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;PGR GO:0006355| regulation of transcription, DNA-dependent NR3C2;AR;ABL1;PGR;NCOA2 4440:[DB06616 DB14635] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes CYP3A4;ABCB1 common pathways GO:0006816| calcium ion transport VDR;CAMK2G GO:0031667| response to nutrient levels SRC;GSTP1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent VDR;ABL1;PPARG GO:0042493| response to drug ABCB1;SRC;CYP1A2;PPARG;LYN GO:0014003| oligodendrocyte development GSTP1;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2B6;CYP1A2;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CBR1;CYP2C8;CYP2D6;CYP1A2;CYP2C9;CYP3A4;CYP2B6 GO:0008209| androgen metabolic process CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;HCK;GSTP1 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0006805| xenobiotic metabolic process CYP1A2;CYP2B6;CYP3A4;CYP2C9;GSTP1;CYP2D6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2B6;CYP2C9 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0071222| cellular response to lipopolysaccharide GSTP1;BCR;SRC;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP1A2;CYP2D6 GO:0007507| heart development PPARG;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG;VDR GO:0045087| innate immune response PPARG;LYN;ABL1;SRC;HCK GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP1A2 GO:0007275| multicellular organismal development CDK2;CAMK2G;VDR GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0010628| positive regulation of gene expression SRC;MAP2K1;VDR GO:0042359| vitamin D metabolic process CYP3A4 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;VDR;SRC GO:0010033| response to organic substance CYP1A2;PPARG;CDK2 GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1;VDR GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0009636| response to toxin LYN;GSTP1 GO:0014070| response to organic cyclic compound LYN;PPARG;CYP1A2 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0002933| CYP2C8;CYP3A4 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;GSTP1;MAP2K2 GO:0055085| transmembrane transport ABCC5;ABCB1 GO:0036378| CYP3A4 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN GO:0007165| signal transduction VDR;MAP2K1;BCR;SRC;LYN;PPARG GO:0017144| drug metabolic process CBR1;CYP2D6;CYP2C8;CYP3A4;CYP2C9;CYP2B6;CYP1A2 GO:0097267| CYP1A2;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP2B6;CYP3A4;CYP2C9;CYP1A2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0006810| transport ABCB1;ABCC5 GO:0042908| xenobiotic transport ABCB1 GO:0032869| cellular response to insulin stimulus GSTP1;SRC;PPARG 4441:[DB06616 DB02813] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways GO:0048477| oogenesis SRC;HEXB GO:0008360| regulation of cell shape HCK;HEXB GO:0050885| neuromuscular process controlling balance BCR;ABL1;HEXB 4442:[DB06616 DB04318] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;MMP11 4443:[DB06616 DB02177] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02177|1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine ITGAL common genes common pathways GO:0006928| cellular component movement MAP2K1;ITGAL GO:0007165| signal transduction MAP2K1;SRC;BCR;ITGAL;LYN GO:0098609| ITGAL;SRC GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1;ITGAL GO:0006954| inflammatory response LYN;ITGAL;HCK GO:0006909| phagocytosis ITGAL;ABL1;HCK GO:0050900| leukocyte migration LYN;ITGAL;SRC GO:0007155| cell adhesion ITGAL;HCK;SRC;ABL1 4444:[DB06616 DB02142] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways 4445:[DB06616 DB12334] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12334|Milataxel TUBB1;TUBB common genes common pathways GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB;CDK2 GO:0051301| cell division CDK2;TUBB GO:0006928| cellular component movement TUBB;MAP2K1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;TUBB 4446:[DB06616 DB06157] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways GO:0006816| calcium ion transport ATP2A2;CAMK2G GO:0042493| response to drug LYN;ATP1A1;SRC;ABCB1 GO:0007155| cell adhesion HCK;SRC;ABL1;ATP2A2 GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0034599| cellular response to oxidative stress ATP2A2;ABL1 GO:0006813| potassium ion transport CDK2;ATP1A1 4447:[DB06616 DB08082] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08082|N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOB GO:0042493| response to drug SRC;ABCB1;MAOB;LYN GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0009636| response to toxin LYN;MAOB 4448:[DB06616 DB07462] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0014070| response to organic cyclic compound COMT;LYN GO:0042493| response to drug SRC;ABCB1;LYN;COMT GO:0032496| response to lipopolysaccharide BCR;COMT 4449:[DB06616 DB09303] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09303|Evolocumab PCSK9 common genes common pathways GO:0006629| lipid metabolic process PCSK9;CYP3A4 GO:0030182| neuron differentiation ABL1;MAP2K1;PCSK9 GO:0006915| apoptotic process PCSK9;ABL1 GO:0008202| steroid metabolic process CYP2C8;PCSK9;CYP3A4 GO:0032869| cellular response to insulin stimulus SRC;PCSK9 4450:[DB06616 DB01284] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01284|Tetracosactide MC2R common genes common pathways GO:0007165| signal transduction LYN;MC2R;MAP2K1;BCR;SRC 4451:[DB06616 DB03484] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03484|L-Alpha-Glycerophosphorylethanolamine ANXA5 common genes common pathways GO:0002576| platelet degranulation ANXA5;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ANXA5 GO:0007165| signal transduction ANXA5;LYN;SRC;BCR;MAP2K1 GO:0007596| blood coagulation LYN;ANXA5 GO:0010033| response to organic substance ANXA5;CDK2 4452:[DB06616 DB05913] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05913|OSI-930 KIT;FLT1 common genes common pathways GO:0006954| inflammatory response HCK;KIT;LYN GO:0000165| MAPKKK cascade KIT;MAP2K1;MAP2K2;CAMK2G GO:0030218| erythrocyte differentiation KIT;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;KIT GO:0019221| cytokine-mediated signaling pathway HCK;KIT GO:0042127| regulation of cell proliferation ABL1;SRC;KIT GO:0007275| multicellular organismal development CAMK2G;CDK2;FLT1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein KIT;LYN GO:0018108| peptidyl-tyrosine phosphorylation FLT1;LYN;MAP2K1;KIT;HCK;MAP2K2;BCR;SRC;ABL1 GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR;KIT GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;FLT1 GO:0006935| chemotaxis MAP2K1;FLT1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;FLT1;HCK;KIT GO:0008360| regulation of cell shape HCK;KIT GO:0016477| cell migration SRC;FLT1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1;KIT GO:0010628| positive regulation of gene expression SRC;KIT;MAP2K1 GO:0046777| protein autophosphorylation LYN;CAMK2G;FLT1;ABL1;KIT;HCK;BCR;SRC GO:0043406| positive regulation of MAP kinase activity FLT1;KIT;SRC GO:0030335| positive regulation of cell migration KIT;LYN;FLT1 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity FLT1;LYN;KIT;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;KIT;LYN;FLT1 GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;KIT;CAMK2G;CDK2;LYN;FLT1;MAP3K2 GO:0030154| cell differentiation FLT1;CAMK2G;HCK GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;FLT1;ABL1;MAP2K1;KIT;HCK;BCR;MAP2K2;SRC GO:0030097| hemopoiesis LYN;KIT GO:0007165| signal transduction BCR;SRC;MAP2K1;KIT;LYN 4453:[DB06616 DB00438] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC15A1;SLC15A2;SLC22A5;SLC22A6;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006810| transport SLC15A1;SLC15A2;ABCB1 4454:[DB06616 DB04010] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04010|2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide PARP1 common genes common pathways GO:0006915| apoptotic process ABL1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:1900182| PARP1;SRC GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:1901216| ABL1;PARP1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 GO:0006281| DNA repair CDK2;PARP1;ABL1 GO:0006974| response to DNA damage stimulus CDK2;LYN;PARP1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 4455:[DB06616 DB06124] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;CAPN3;MAP2K1;MAP2K2;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;CAPN3 GO:0006915| apoptotic process ABL1;CAPN3 GO:0045892| negative regulation of transcription, DNA-dependent SRC;CAPN3 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CAPN3 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;CAPN3 4456:[DB06616 DB12200] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12200|Tivantinib MET common genes common pathways GO:0000165| MAPKKK cascade MET;CAMK2G;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MET GO:0035635| entry of bacterium into host cell MET;SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;MET GO:0008283| cell proliferation MET;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;MET;LYN GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;MET;CDK2;LYN;CAMK2G GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;LYN;HCK 4457:[DB06616 DB06366] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06366|Pertuzumab ERBB2 common genes common pathways GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;ERBB2;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade SRC;ERBB2 GO:0038128| ERBB2;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;ERBB2 GO:0001934| positive regulation of protein phosphorylation ERBB2;ABL1;LYN GO:2000145| regulation of cell motility ABL1;ERBB2 GO:0007507| heart development ERBB2;MAP2K1 GO:0007399| nervous system development ERBB2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ERBB2;ABL1;LYN GO:0010628| positive regulation of gene expression MAP2K1;SRC;ERBB2 GO:0046777| protein autophosphorylation HCK;SRC;BCR;ABL1;ERBB2;LYN;CAMK2G GO:0043406| positive regulation of MAP kinase activity SRC;ERBB2 GO:0008283| cell proliferation SRC;ERBB2 GO:0045785| positive regulation of cell adhesion SRC;ERBB2 GO:0070372| regulation of ERK1 and ERK2 cascade ERBB2;LYN GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;ERBB2 GO:0043547| positive regulation of GTPase activity BCR;ERBB2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;ERBB2 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;ERBB2;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ERBB2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK 4458:[DB06616 DB04590] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F7 GO:0031667| response to nutrient levels F7;SRC GO:0009725| response to hormone stimulus LYN;F7 GO:0030335| positive regulation of cell migration LYN;F7 GO:0014070| response to organic cyclic compound F7;LYN GO:0007596| blood coagulation LYN;F7 4459:[DB06616 DB05668] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05668|Palifosfamide DNMT1 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;DNMT1 GO:0045892| negative regulation of transcription, DNA-dependent DNMT1;SRC GO:0006355| regulation of transcription, DNA-dependent DNMT1;ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1;DNMT1 GO:0007265| Ras protein signal transduction CDK2;DNMT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;CDK2 4460:[DB06616 DB04758] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0007596| blood coagulation LYN;F7 GO:0014070| response to organic cyclic compound F7;LYN GO:0009725| response to hormone stimulus LYN;F7 GO:0030335| positive regulation of cell migration F7;LYN GO:0051897| positive regulation of protein kinase B signaling cascade F7;SRC GO:0031667| response to nutrient levels SRC;F7 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC 4461:[DB06616 DB05404] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05404|AZD 3355 TP53 common genes common pathways GO:0006915| apoptotic process TP53;ABL1 GO:0043200| response to amino acid stimulus TP53;LYN GO:0014070| response to organic cyclic compound LYN;TP53 GO:0008283| cell proliferation TP53;SRC GO:0007049| cell cycle CDK2;TP53;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;TP53 GO:0045892| negative regulation of transcription, DNA-dependent TP53;SRC GO:0010628| positive regulation of gene expression TP53;SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species TP53;SRC GO:0030154| cell differentiation CAMK2G;TP53;HCK GO:0071456| cellular response to hypoxia TP53;SRC GO:0034605| cellular response to heat LYN;TP53 GO:0007050| cell cycle arrest TP53;ABL1;MAP2K1 GO:0006979| response to oxidative stress ABL1;TP53 GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;TP53 GO:0006914| autophagy ABL1;TP53 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2;TP53 GO:0042493| response to drug ABCB1;SRC;TP53;LYN GO:0006355| regulation of transcription, DNA-dependent TP53;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TP53;LYN;SRC;ABL1 GO:0016032| viral reproduction HCK;SRC;TP53;LYN GO:0007275| multicellular organismal development TP53;CAMK2G;CDK2 GO:0007265| Ras protein signal transduction CDK2;TP53 GO:0051974| negative regulation of telomerase activity SRC;TP53 GO:0006974| response to DNA damage stimulus TP53;CDK2;LYN;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP53;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;TP53;MAP3K2 GO:0031571| mitotic cell cycle G1/S transition DNA damage checkpoint TP53;CDK2 GO:0043066| negative regulation of apoptotic process TP53;SRC;HCK GO:1901796| CDK2;TP53 GO:0043065| positive regulation of apoptotic process SRC;ABL1;TP53 4462:[DB06616 DB06101] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;KDR;MAP2K1;FLT4 GO:0016477| cell migration FLT1;SRC GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0043406| positive regulation of MAP kinase activity SRC;FLT1 GO:0046777| protein autophosphorylation FLT1;LYN;FLT4;CAMK2G;KDR;HCK;BCR;SRC;ABL1 GO:0030154| cell differentiation FLT1;CAMK2G;HCK;KDR GO:0006468| protein phosphorylation MAP3K2;FLT1;FLT4;CDK2;LYN;CAMK2G;HCK;KDR;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0030335| positive regulation of cell migration KDR;LYN;FLT1 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN;FLT1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT1;LYN;FLT4;KDR;HCK GO:0010595| positive regulation of endothelial cell migration FLT4;KDR;ABL1 GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;KDR;MAP2K1;ABL1;FLT1;MAP3K2;CAMK2G;FLT4;CDK2;LYN GO:0001934| positive regulation of protein phosphorylation FLT4;LYN;ABL1;KDR GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;KDR GO:0038083| ABL1;SRC;KDR;HCK;LYN GO:0016032| viral reproduction KDR;HCK;SRC;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0007275| multicellular organismal development CDK2;CAMK2G;FLT1;KDR GO:0018108| peptidyl-tyrosine phosphorylation FLT1;LYN;FLT4;MAP2K1;KDR;HCK;MAP2K2;BCR;SRC;ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0008360| regulation of cell shape KDR;HCK GO:0043066| negative regulation of apoptotic process FLT4;SRC;HCK;KDR GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR;FLT1;FLT4 GO:0008284| positive regulation of cell proliferation FLT1;CDK2;LYN;FLT4;KDR;HCK GO:0006935| chemotaxis MAP2K1;FLT1 4463:[DB06616 DB03691] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03691|WRR-112 CTSF common genes common pathways 4464:[DB06616 DB04461] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04461|Coproporphyrinogen III UROD common genes common pathways 4465:[DB06616 DB07039] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;AR;HCK GO:0042327| positive regulation of phosphorylation LYN;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0051259| protein oligomerization CAMK2G;AR GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation SRC;AR GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;AR GO:0006810| transport AR;ABCB1 4466:[DB06616 DB11059] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC2A1 GO:0032868| response to insulin stimulus SLC2A1;LYN GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0071260| cellular response to mechanical stimulus SLC2A1;MAP3K2 4467:[DB06616 DB04325] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04325|Phenethylamine PRSS2;PRSS1 common genes common pathways GO:0045785| positive regulation of cell adhesion PRSS2;SRC 4468:[DB06616 DB06973] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06973|4,4'-PROPANE-2,2-DIYLDIPHENOL ESRRG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;ESRRG GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;ESRRG;MAP2K1;CDK2;MAP3K2 4469:[DB06616 DB03403] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways GO:0016310| phosphorylation CDK2;LYN;CMPK1;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;UCK2;MAP2K2 4470:[DB06616 DB00685] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;LYN;ABCB1;SRC GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006974| response to DNA damage stimulus LYN;CDK2;TOP2A;ABL1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0043065| positive regulation of apoptotic process TOP2A;ABL1;SRC GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 4471:[DB06616 DB02712] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02712|Sorbinil AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 4472:[DB06616 DB08497] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0030216| keratinocyte differentiation MAP2K1;CASP3 GO:0030182| neuron differentiation MAP2K1;CASP3;ABL1 GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0006915| apoptotic process ABL1;CASP3 GO:0010033| response to organic substance CASP3;CDK2 GO:0030889| negative regulation of B cell proliferation LYN;CASP3 GO:0042493| response to drug SRC;ABCB1;CASP3;LYN GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0030218| erythrocyte differentiation LYN;CASP3 GO:0001782| B cell homeostasis LYN;CASP3 GO:0032496| response to lipopolysaccharide CASP3;BCR GO:0042542| response to hydrogen peroxide SRC;CASP3 GO:0043065| positive regulation of apoptotic process ABL1;SRC;CASP3 GO:0043066| negative regulation of apoptotic process HCK;CASP3;SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;CASP3;BCR;SRC GO:0007507| heart development CASP3;MAP2K1 GO:0006974| response to DNA damage stimulus ABL1;CASP3;CDK2;LYN 4473:[DB06616 DB08155] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0071498| cellular response to fluid shear stress SRC;CA2 GO:0010033| response to organic substance CDK2;CA2 4474:[DB06616 DB04109] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04109|[4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]Benzamidine PRSS3 common genes common pathways GO:0043542| endothelial cell migration PRSS3;ABL1 4475:[DB06616 DB07428] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0007596| blood coagulation LYN;HBB GO:0042542| response to hydrogen peroxide SRC;HBA1;HBB 4476:[DB06616 DB04074] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0050900| leukocyte migration LYN;SLC16A3;SRC;SLC16A1 GO:0055085| transmembrane transport SLC16A1;ABCB1;SLC16A3;SLC16A7 4477:[DB06616 DB02180] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02180|Myristoyl-Coa NMT1;NMT2 common genes common pathways 4478:[DB06616 DB03239] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways GO:0006810| transport ABCB1;TTR 4479:[DB06616 DB01102] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1;ADRB2 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0007165| signal transduction BCR;SRC;ADRB1;MAP2K1;ADRB3;ADRB2;LYN GO:0045453| bone resorption ADRB2;SRC 4480:[DB06616 DB04843] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0008283| cell proliferation SRC;CHRM1;CHRM3 GO:0007165| signal transduction SRC;BCR;MAP2K1;CHRM1;LYN;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;LYN;CDK2;HCK GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1 4481:[DB06616 DB07067] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;DPP4;CDK2;LYN GO:0007155| cell adhesion DPP4;SRC;HCK;ABL1 GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation SRC;DPP4;LYN 4482:[DB06616 DB05191] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05191|Atl146e ADORA2A common genes common pathways GO:0007417| central nervous system development SRC;ADORA2A;LYN GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ADORA2A GO:0007596| blood coagulation LYN;ADORA2A GO:0006915| apoptotic process ADORA2A;ABL1 GO:0008285| negative regulation of cell proliferation LYN;ADORA2A;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;ABL1 GO:0042493| response to drug ABCB1;SRC;ADORA2A;LYN GO:0006909| phagocytosis HCK;ABL1;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;ADORA2A GO:0050728| negative regulation of inflammatory response ADORA2A;BCR GO:0006954| inflammatory response HCK;LYN;ADORA2A GO:0051924| regulation of calcium ion transport CAMK2G;ADORA2A 4483:[DB06616 DB01834] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0007417| central nervous system development GSTP1;SRC;LYN GO:0032869| cellular response to insulin stimulus SRC;GSTP1 GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0009636| response to toxin LYN;GSTP1 GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;GSTP1;ABL1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;GSTP1;MAP2K1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;GSTP1 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0034599| cellular response to oxidative stress GSTP1;ABL1 GO:0014003| oligodendrocyte development GSTP1;LYN GO:0031667| response to nutrient levels GSTP1;SRC 4484:[DB06616 DB12458] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways GO:0009791| post-embryonic development GABRG2;ABL1 GO:0007165| signal transduction GABRB3;BCR;SRC;MAP2K1;LYN GO:0006810| transport ABCB1;GABRB3;GABRG2;GABRA1 4485:[DB06616 DB00655] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes CYP3A4;ABCB1 common pathways GO:0014070| response to organic cyclic compound CYP1A1;LYN;CYP1A2 GO:0009636| response to toxin CYP1B1;LYN;SLC22A8;CYP1A1 GO:0002933| CYP2C8;CYP3A5;CYP1A1;CYP3A4 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC;CYP1A1 GO:0055085| transmembrane transport SLCO1A2;SLCO1B1;SLC22A8;ABCB1;ABCG2;SLCO2B1 GO:0036378| CYP3A4 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0030336| negative regulation of cell migration BCR;CYP1B1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;CYP1B1;AR GO:0010033| response to organic substance CYP1A2;CDK2;CYP1A1 GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP1A1;CYP2C9;CYP3A4;CYP2B6;CYP1B1;CYP3A5;CYP2C8 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1;ABCG2;AR GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0070989| oxidative demethylation CYP1A2;CYP2C9;CYP3A4;CYP2C8;CYP3A5 GO:0007165| signal transduction ESR1;LYN;AR;ESR2;BCR;SRC;MAP2K1 GO:0097267| CYP2C9;CYP1A1;CYP4A11;CYP1A2;CYP2C8;CYP1B1 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1;CYP1A1;CYP2C9;CYP2B6;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;ESR2;AR;MAP3K2;CDK2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;AR;ABL1 GO:0042493| response to drug ABCG2;SRC;ABCB1;CYP1A1;CYP2E1;LYN;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4;CYP2C9;CYP2B6 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A5;CYP1B1;CYP2B6;CYP3A4;CYP19A1;CYP1A1;CYP2C9;CYP2E1;CYP1A2;CYP4A11 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2E1;CYP1A2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide BCR;CYP1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0051259| protein oligomerization AR;CAMK2G GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0042737| drug catabolic process CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0042327| positive regulation of phosphorylation LYN;AR GO:0060065| uterus development ESR1;CYP19A1;SRC GO:0006805| xenobiotic metabolic process CYP2B6;CYP2E1;CYP2C9;CYP3A4;CYP1A2;CYP2C8;CYP3A5;CYP1B1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP4A11;CYP2C9;CYP1A1;CYP2E1;CYP2B6;CYP1B1;CYP2C8 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;AR GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0009615| response to virus CYP1A1;SRC GO:0043065| positive regulation of apoptotic process SRC;CYP1B1;ABL1 GO:0002576| platelet degranulation ALB;LYN GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP2C9;CYP3A4 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;AR;ESR1;CDK2 GO:0007155| cell adhesion ABL1;HCK;CYP1B1;SRC 4486:[DB06616 DB03268] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03268|RU82197 SRC common genes SRC common pathways GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1 GO:2000386| positive regulation of ovarian follicle development SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0045453| bone resorption SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0036120| SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0060491| regulation of cell projection assembly SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0043406| positive regulation of MAP kinase activity SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0045087| innate immune response LYN;HCK;SRC;ABL1 GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion ABL1;HCK;SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0035635| entry of bacterium into host cell SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR GO:0071398| cellular response to fatty acid SRC GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0038096| SRC;HCK;ABL1;LYN GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071498| cellular response to fluid shear stress SRC GO:0016032| viral reproduction LYN;SRC;HCK GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0050900| leukocyte migration LYN;SRC GO:0034332| adherens junction organization SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0042493| response to drug ABCB1;SRC;LYN GO:0038083| ABL1;HCK;SRC;LYN GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2 4487:[DB06616 DB03225] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03225|D-Tryptophan DAO;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 GO:0055114| oxidation-reduction process DAO;CYP2C8;CYP3A4 4488:[DB06616 DB00902] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00902|Methdilazine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;LYN;HCK GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0007165| signal transduction LYN;HRH1;MAP2K1;SRC;BCR 4489:[DB06616 DB03593] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03593|N7-Methyl-Guanosine-5'-Monophosphate DCPS common genes common pathways 4490:[DB06616 DB05087] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0007417| central nervous system development LYN;GABRA4;SRC GO:0006810| transport GABRA5;GABRA3;GABRA1;GABRA6;GABRA4;ABCB1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;GABRA6;GABRA5 GO:0007420| brain development BCR;GABRA5 4491:[DB06616 DB04840] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2C8;CYP2D6 GO:0045332| phospholipid translocation ABCB1 GO:0006810| transport ABCB1;SLC6A2 GO:0042908| xenobiotic transport ABCB1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2C8;CYP2D6 GO:0008283| cell proliferation SRC;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;LYN GO:0009636| response to toxin CYP1A1;LYN GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance CYP1A1;CDK2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide BCR;CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0009615| response to virus CYP1A1;SRC GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0042493| response to drug LYN;CYP1A1;SLC6A2;ABCB1;SRC GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;CYP2C8;CYP2D6 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 4492:[DB06616 DB04562] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04562|Tricarballylic Acid ACO2 common genes common pathways 4493:[DB06616 DB09304] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09304|Setiptiline ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7 common genes common pathways GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;HTR2A;LYN GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K2;MAP2K1 GO:0016032| viral reproduction HTR2A;LYN;HCK;SRC GO:0042493| response to drug HTR2A;LYN;HTR2C;HTR2B;ABCB1;HTR1B;SRC GO:0007507| heart development HTR2B;MAP2K1 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;ADRA2A;SRC GO:0008284| positive regulation of cell proliferation ADRA2A;HTR2B;HCK;HTR1A;CDK2;LYN;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;SRC;HCK GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A;HTR2B;HTR2A GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;HTR2C;HTR2B;ABL1;MAP2K1;MAP2K2;SRC GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0008283| cell proliferation SRC;HTR1A GO:0009636| response to toxin LYN;HTR1D GO:0007165| signal transduction HTR3C;HTR1A;ADRA2C;HTR2A;LYN;ADRA2B;HTR3E;HTR4;HTR1D;HTR2C;HTR2B;HTR6;ADRA2A;HTR1F;HTR1E;BCR;HTR1B;SRC;HTR3D;MAP2K1;HTR3B;HTR7;HTR3A GO:0050715| positive regulation of cytokine secretion HTR2B;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0030168| platelet activation ADRA2C;ADRA2B;LYN;SRC;ADRA2A GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;HTR2B;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0043547| positive regulation of GTPase activity BCR;HTR2B GO:0030335| positive regulation of cell migration ADRA2A;LYN 4494:[DB06616 DB00886] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00886|Omapatrilat ACE;MME common genes common pathways 4495:[DB06616 DB01626] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01626|Pargyline MAOB;MAOA common genes common pathways GO:0009636| response to toxin MAOB;LYN GO:0042493| response to drug LYN;MAOB;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOB;MAOA GO:0032496| response to lipopolysaccharide BCR;MAOB 4496:[DB06616 DB14642] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0010628| positive regulation of gene expression SRC;AVPR2;MAP2K1 GO:0010033| response to organic substance CDK2;AVPR1A GO:0006810| transport ABCB1;ABCC2 GO:0007204| elevation of cytosolic calcium ion concentration AVPR1B;AVPR1A;ABL1 GO:0006979| response to oxidative stress ABCC2;ABL1 GO:0007165| signal transduction AVPR1A;LYN;AVPR1B;BCR;SRC;MAP2K1;AVPR2 GO:0042493| response to drug LYN;ABCC2;ABCB1;SRC GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:0008284| positive regulation of cell proliferation AVPR2;HCK;AVPR1A;LYN;CDK2 GO:0071222| cellular response to lipopolysaccharide ABCC2;ABL1;SRC;BCR 4497:[DB06616 DB04865] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 4498:[DB06616 DB06536] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0032868| response to insulin stimulus LYN;PPARA GO:0014070| response to organic cyclic compound PPARG;LYN GO:0007165| signal transduction LYN;PPARG;MAP2K1;BCR;SRC GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0050728| negative regulation of inflammatory response PPARA;BCR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG;PPARA;MAP3K2;MAP2K1;MAP2K2;SRC GO:0042493| response to drug LYN;PPARG;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG;ABL1 GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PPARA;CDK2 GO:0045087| innate immune response ABL1;SRC;HCK;PPARG;LYN GO:0007507| heart development MAP2K1;PPARA;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC 4499:[DB06616 DB01081] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01081|Diphenoxylate OPRM1;OPRD1 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;OPRM1 GO:0007165| signal transduction SRC;BCR;MAP2K1;OPRM1;OPRD1;LYN GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0010629| negative regulation of gene expression OPRD1;MAP2K2;MAP2K1 GO:0032496| response to lipopolysaccharide OPRM1;BCR 4500:[DB06616 DB08760] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PPARG GO:0007507| heart development MAP2K1;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;SRC;ABL1 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0009612| response to mechanical stimulus PPARG;SRC GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;PPARG;CDK2;MAP3K2 GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction BCR;SRC;MAP2K1;PPARG;LYN GO:0014070| response to organic cyclic compound PPARG;LYN GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1 GO:0010033| response to organic substance CDK2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC 4501:[DB06616 DB12945] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 4502:[DB06616 DB04889] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0030900| forebrain development DRD2;SRC GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007420| brain development BCR;SLC6A4 GO:0007165| signal transduction LYN;MAP2K1;SRC;DRD2;BCR GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0006810| transport ABCB1;SLC6A2 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0010628| positive regulation of gene expression SLC6A4;MAP2K1;SRC GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0055085| transmembrane transport SLC6A2;SLC6A4;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;DRD2;SRC;MAP2K2;ABL1 GO:0009636| response to toxin SLC6A4;DRD2;LYN;MAOB GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0035556| intracellular signal transduction SRC;DRD2;BCR;CAMK2G;LYN GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0048678| response to axon injury LYN;DRD2 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8;CYP2D6 GO:0042493| response to drug MAOB;SLC6A2;LYN;DRD2;SRC;ABCB1;SLC6A4 4503:[DB06616 DB00782] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00782|Propantheline CHRM1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRM1;LYN GO:0006464| protein modification process CHRM1;ABL1 GO:0008283| cell proliferation CHRM1;SRC GO:0007399| nervous system development CAMK2G;CHRM1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRM1;HCK 4504:[DB06616 DB00422] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00422|Methylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0007420| brain development SLC6A4;BCR GO:0055085| transmembrane transport SLC6A4;SLC6A3;ABCB1;SLC6A2 GO:0009636| response to toxin LYN;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0010033| response to organic substance CDK2;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0042493| response to drug LYN;SLC6A2;SLC6A3;SLC6A4;SRC;ABCB1 4505:[DB06616 DB07642] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07642|5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 4506:[DB06616 DB14508] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007275| multicellular organismal development GSK3B;CAMK2G;CDK2 GO:0007399| nervous system development CAMK2G;GSK3B GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;GSK3B;MAP3K2 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;GSK3B;SRC GO:0043066| negative regulation of apoptotic process GSK3B;HCK;SRC GO:0035556| intracellular signal transduction BCR;SRC;GSK3B;LYN;CAMK2G GO:1901216| GSK3B;ABL1 GO:0030154| cell differentiation CAMK2G;HCK;GSK3B GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;GSK3B;ABL1 GO:0006810| transport ABCB1;GRIA3 GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;GSK3B;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0043547| positive regulation of GTPase activity BCR;GSK3B GO:0007165| signal transduction MAP2K1;BCR;SRC;IMPA1;IMPA2;LYN GO:1900034| GSK3B;CAMK2G GO:0018107| peptidyl-threonine phosphorylation GSK3B;MAP2K1;CAMK2G GO:0031175| neuron projection development GSK3B;LYN GO:0046777| protein autophosphorylation HCK;BCR;SRC;GSK3B;ABL1;LYN;CAMK2G GO:0010628| positive regulation of gene expression GSK3B;SRC;MAP2K1 4507:[DB06616 DB04872] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04872|Osanetant TACR3 common genes common pathways GO:0007165| signal transduction LYN;SRC;BCR;TACR3;MAP2K1 4508:[DB06616 DB04187] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways 4509:[DB06616 DB01569] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01569|Formebolone HSD11B2 common genes common pathways GO:0032868| response to insulin stimulus LYN;HSD11B2 GO:0055114| oxidation-reduction process CYP3A4;HSD11B2;CYP2C8 GO:0042493| response to drug ABCB1;SRC;HSD11B2;LYN 4510:[DB06616 DB03414] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03414|5-Thio-a/B-D-Mannopyranosylamine MAN2A1 common genes common pathways 4511:[DB06616 DB05434] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein VEGFA;LYN GO:0018108| peptidyl-tyrosine phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;HGF;ABL1;FGF2;LYN GO:0007275| multicellular organismal development VEGFA;FGF2;CDK2;CAMK2G GO:0007498| mesoderm development HCK;VEGFA GO:2000573| positive regulation of DNA biosynthetic process SRC;HGF GO:0007265| Ras protein signal transduction CDK2;FGF2 GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA GO:0007399| nervous system development CAMK2G;VEGFA;FGF2 GO:0008360| regulation of cell shape VEGFA;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VEGFA GO:0042327| positive regulation of phosphorylation VEGFA;LYN GO:0043066| negative regulation of apoptotic process HGF;SRC;HCK;VEGFA GO:0051272| positive regulation of cellular component movement VEGFA;LYN GO:0030155| regulation of cell adhesion CXCL8;ABL1 GO:0048010| vascular endothelial growth factor receptor signaling pathway VEGFA;SRC GO:0035556| intracellular signal transduction BCR;CXCL8;SRC;LYN;CAMK2G GO:0008284| positive regulation of cell proliferation HGF;HCK;CDK2;LYN;VEGFA;FGF2 GO:0006935| chemotaxis FGF2;CXCL8;MAP2K1 GO:0071222| cellular response to lipopolysaccharide CXCL8;BCR;SRC;ABL1 GO:0002576| platelet degranulation HGF;LYN;VEGFA GO:0001934| positive regulation of protein phosphorylation LYN;VEGFA;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process HGF;SRC;VEGFA GO:0000278| mitotic cell cycle ABL1;HGF GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;FGF2;CDK2 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;VEGFA GO:0051897| positive regulation of protein kinase B signaling cascade HGF;SRC;FGF2 GO:0000165| MAPKKK cascade FGF2;CAMK2G;MAP2K2;MAP2K1;HGF GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;LYN;SRC;ABL1;HGF GO:0031954| positive regulation of protein autophosphorylation VEGFA;SRC GO:0006954| inflammatory response LYN;HCK;CXCL8 GO:0050728| negative regulation of inflammatory response HGF;BCR GO:0071456| cellular response to hypoxia SRC;VEGFA GO:0030154| cell differentiation CAMK2G;VEGFA;FGF2;HCK GO:0030335| positive regulation of cell migration HGF;LYN;VEGFA GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;FGF2;LYN GO:0072089| stem cell proliferation FGF2;ABCB1 GO:0010595| positive regulation of endothelial cell migration VEGFA;ABL1 GO:0007050| cell cycle arrest CXCL8;MAP2K1;ABL1 GO:0007165| signal transduction FGF2;LYN;MAP2K1;SRC;BCR;CXCL8 GO:0000187| activation of MAPK activity MAP3K2;FGF2;MAP2K1;MAP2K2;HGF GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF2;VEGFA;MAP2K2;SRC;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion VEGFA;SRC GO:0008283| cell proliferation HGF;SRC GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;CXCL8 GO:0043406| positive regulation of MAP kinase activity VEGFA;FGF2;SRC GO:0006928| cellular component movement CXCL8;MAP2K1 GO:0010628| positive regulation of gene expression VEGFA;SRC;MAP2K1 4512:[DB06616 DB06731] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06731|Seproxetine CYP3A5;CYP3A7;CYP2C9;CYP2C19 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C19;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP3A5;CYP2C8 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2C9;CYP3A5;CYP2C8;CYP2C19 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2C9;CYP2C19;CYP2C8;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A5;CYP3A7;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4 4513:[DB06616 DB04760] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04760|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways 4514:[DB06616 DB06211] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0071732| cellular response to nitric oxide DPEP1;CDK2 GO:0043066| negative regulation of apoptotic process DPEP1;SRC;HCK GO:0006805| xenobiotic metabolic process DPEP1;CYP3A4;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process DPEP1;SRC GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A8;ABCB1 GO:0006915| apoptotic process DPEP1;ABL1 GO:0030336| negative regulation of cell migration BCR;DPEP1 4515:[DB06616 DB00517] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0006464| protein modification process CHRM3;CHRM1;ABL1 GO:0008283| cell proliferation CHRM3;CHRM1;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;CHRM2;LYN;CHRM1;CHRM3 GO:0009615| response to virus SRC;CHRM2 GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0007399| nervous system development CHRM1;CAMK2G;CHRM2;CHRM3 4516:[DB06616 DB00131] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0016032| viral reproduction SRC;HCK;CREB1;LYN GO:0045893| positive regulation of transcription, DNA-dependent CDK2;CREB1;MAP3K2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent HINT1;CREB1;ABL1;PRKAA1 GO:0016236| macroautophagy PRKAB2;PRKAB1;SRC;PRKAA1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;CREB1 GO:0007346| regulation of mitotic cell cycle MAP3K2;PIM1;MAP2K1;MAP2K2 GO:0042493| response to drug SRC;ABCB1;ADCY1;ACSL1;CREB1;LYN GO:0006914| autophagy PRKAA1;ABL1 GO:0050900| leukocyte migration PDE4D;LYN;SRC;PDE4B GO:0043066| negative regulation of apoptotic process SRC;PRKAA1;HCK;PIM1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;SRC GO:0071398| cellular response to fatty acid CREB1;SRC GO:0035556| intracellular signal transduction ADCY1;SRC;BCR;LYN;CAMK2G GO:0071222| cellular response to lipopolysaccharide PDE4B;ABL1;BCR;SRC;PDE4D GO:0042542| response to hydrogen peroxide SRC;PRKAA1 GO:0008284| positive regulation of cell proliferation PRKAA1;HCK;LYN;CDK2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;CREB1 GO:1901796| PRKAB1;PRKAB2;PRKAA1;CDK2 GO:0006629| lipid metabolic process CYP3A4;PRKAA1;PRKAB1;PRKAB2;ACSL1 GO:0042981| regulation of apoptotic process CREB1;MAP3K2;MAP2K1;MAP2K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;CDK2 GO:0007275| multicellular organismal development PIM1;CDK2;CAMK2G GO:0010628| positive regulation of gene expression PRKAB1;SRC;PRKAA1;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity ACSL1;MAP2K1;SRC;MAP2K2 GO:0046777| protein autophosphorylation CAMK2G;LYN;PIM1;ABL1;BCR;SRC;HCK GO:0010033| response to organic substance ACSL1;AMPD1;CREB1;CDK2 GO:0007049| cell cycle SRC;CDK2;PIM1 GO:0007411| axon guidance CREB1;SRC GO:0070301| cellular response to hydrogen peroxide ABL1;PRKAA1 GO:0014070| response to organic cyclic compound ACSL1;LYN GO:0008283| cell proliferation SRC;PIM1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CREB1 GO:0006915| apoptotic process HINT1;PIM1;ABL1 GO:0000187| activation of MAPK activity MAP2K2;PRKAA1;MAP2K1;MAP3K2 GO:0007050| cell cycle arrest PRKAB1;ABL1;PRKAB2;PRKAA1;MAP2K1 GO:0007165| signal transduction PDE4D;LYN;CREB1;HINT1;ADCY1;MAP2K1;SRC;PRKAA1;BCR;PRKAB2;PDE4B;PRKAB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;PRKAA1 GO:0016310| phosphorylation CAMK2G;LYN;CDK2;PIM1;MAP3K2;ABL1;ADK;SRC;BCR;MAP2K2;PRKAA1;HCK;MAP2K1 GO:0036120| SRC;CREB1 GO:0071456| cellular response to hypoxia PRKAA1;SRC GO:0032869| cellular response to insulin stimulus SRC;APRT GO:0006468| protein phosphorylation PIM1;MAP3K2;CAMK2G;CREB1;CDK2;LYN;BCR;MAP2K2;PRKAA1;SRC;MAP2K1;HCK;PRKAB1;PRKAB2;ABL1 GO:0030154| cell differentiation HCK;CREB1;CAMK2G 4517:[DB06616 DB00594] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;AOC1 GO:0042493| response to drug LYN;AOC1;ABCB1;SRC GO:0006816| calcium ion transport CAMK2G;ASIC1 GO:0051259| protein oligomerization SLC9A1;CAMK2G GO:0042127| regulation of cell proliferation SRC;PLAU;ABL1 GO:0071260| cellular response to mechanical stimulus SLC9A1;MAP3K2 GO:0006935| chemotaxis MAP2K1;PLAU GO:0043065| positive regulation of apoptotic process SRC;SLC9A1;ABL1 GO:0043066| negative regulation of apoptotic process ASIC2;SLC9A1;HCK;SRC GO:0009612| response to mechanical stimulus SRC;ASIC2 GO:0006805| xenobiotic metabolic process AOC1;CYP3A4;CYP2C8 GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0055085| transmembrane transport SLC22A4;SLC22A2;SLC9A1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0007596| blood coagulation PLAU;LYN GO:0014070| response to organic cyclic compound LYN;SLC9A1 GO:0016477| cell migration SLC9A1;SRC GO:0010447| response to acidity ASIC2;ASIC1;SRC;SLC9A1 GO:0071456| cellular response to hypoxia SLC9A1;SRC GO:0032869| cellular response to insulin stimulus SLC9A1;SRC GO:0030154| cell differentiation CAMK2G;SLC9A1;HCK GO:0006810| transport ABCB1;ASIC1 GO:0007417| central nervous system development SRC;LYN;ASIC2 GO:0030335| positive regulation of cell migration LYN;PLAU GO:0007165| signal transduction LYN;ASIC1;PLAU;MAP2K1;BCR;SRC GO:1902533| SRC;SLC9A1 4518:[DB06616 DB06288] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0035556| intracellular signal transduction BCR;DRD2;SRC;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation HTR2A;LYN;CDK2;DRD3;HCK GO:0048678| response to axon injury LYN;DRD2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0016032| viral reproduction HTR2A;LYN;HCK;SRC GO:0042493| response to drug ABCB1;SRC;DRD2;DRD3;HTR2A;LYN GO:0030900| forebrain development DRD2;SRC GO:0007165| signal transduction HTR2A;LYN;DRD3;MAP2K1;HTR7;BCR;SRC;DRD2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0030336| negative regulation of cell migration DRD2;BCR GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K1;SRC;DRD2;MAP2K2;ABL1 GO:0009636| response to toxin DRD2;LYN 4519:[DB06616 DB11358] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FADS1;FADS2;ELOVL5 GO:0006355| regulation of transcription, DNA-dependent ABL1;FADS1 GO:0055114| oxidation-reduction process CYP3A4;FADS1;CYP2C8;FADS2 4520:[DB06616 DB09205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09205|Moxisylyte ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;BCHE common genes common pathways GO:0035556| intracellular signal transduction BCR;ADRA1A;SRC;ADRA1B;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;ADRA1D;ADRA2A;HCK GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2C;ADRA2B GO:0007275| multicellular organismal development ADRA1D;CAMK2G;CDK2;ADRA1B GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0042493| response to drug LYN;BCHE;SRC;ADRA1A;ABCB1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction ADRA2A;ADRA1B;ADRA1A;SRC;BCR;MAP2K1;ADRA2C;ADRA2B;LYN;ADRA1D GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0030168| platelet activation SRC;ADRA2A;ADRA2B;LYN;ADRA2C GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ABL1;ADRA1B;ADRA1A GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;LYN;BCHE GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;ADRA2B GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;ADRA1A;MAP2K2 4521:[DB06616 DB03059] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03059|Acetoacetyl-CoA HADH;ACADS;ECHS1 common genes common pathways GO:0006629| lipid metabolic process ECHS1;ACADS;HADH;CYP3A4 GO:0042493| response to drug HADH;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process HADH;CYP3A4;ACADS;CYP2C8 GO:0009725| response to hormone stimulus HADH;LYN GO:0032868| response to insulin stimulus HADH;LYN 4522:[DB06616 DB04066] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways GO:0055114| oxidation-reduction process PTGR1;CYP2C8;CYP3A4 4523:[DB06616 DB09282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0035556| intracellular signal transduction GUCY1A2;LYN;CAMK2G;SRC;BCR GO:0007165| signal transduction MAP2K1;SRC;BCR;PDE5A;GUCY1A2;LYN GO:0043406| positive regulation of MAP kinase activity PDE5A;SRC 4524:[DB06616 DB00630] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0007155| cell adhesion HCK;SRC;ABL1;PTPRS GO:0016032| viral reproduction LYN;SRC;FDPS;HCK GO:0008202| steroid metabolic process CYP3A4;CYP2C8;FDPS GO:0006810| transport ABCB1;ATP6V1A GO:0006470| protein dephosphorylation PTPRE;PTPN4;CAMK2G;PTPRS 4525:[DB06616 DB00237] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;MAP2K1;MAP2K2;MAP3K2 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;CHRNA7 GO:0009636| response to toxin GABRB1;LYN GO:0009791| post-embryonic development ABL1;GABRG2 GO:0006810| transport GABRB3;ABCB1;GABRD;GABRB2;GABRA4;GABRA6;GRIK2;GABRA1;GABRA3;GABRG2;GABRB1;GABRA5 GO:0007417| central nervous system development SRC;LYN;GABRA4 GO:0007165| signal transduction GABRB3;CHRNA7;GRIA2;CHRNA4;SRC;BCR;MAP2K1;GABRD;GABRA6;GABRP;LYN;GABRE;GABRQ;GABRB1;GABRA5 GO:0007420| brain development GABRA5;BCR GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1;LYN GO:0042493| response to drug SRC;ABCB1;GABRG3;LYN GO:0006816| calcium ion transport CHRNA4;CHRNA7;CAMK2G GO:0006281| DNA repair CHRNA4;ABL1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;CHRNA7;CDK2;LYN 4526:[DB06616 DB06098] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06098|PRLX 93936 VDAC2;VDAC3 common genes common pathways GO:0055085| transmembrane transport VDAC2;VDAC3;ABCB1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;VDAC2 4527:[DB06616 DB08326] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ACSBG1 4528:[DB06616 DB08846] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes common pathways GO:0006816| calcium ion transport CAMK2G;PRKCB GO:0016032| viral reproduction SYK;LYN;HCK;SRC GO:0006954| inflammatory response HCK;SYK;LYN GO:0090330| regulation of platelet aggregation PRKCA;LYN;SYK GO:0002250| adaptive immune response PRKCB;SYK;LYN GO:0071498| cellular response to fluid shear stress SRC;CA2 GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;SYK GO:0038128| SRC;PRKCA GO:0038096| LYN;SYK;ABL1;HCK;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;PRKCB;CSNK2A1 GO:0016236| macroautophagy SRC;CSNK2A1 GO:0042493| response to drug ABCB1;SRC;CA9;CYP2E1;CYP1A1;LYN GO:0038083| HCK;SRC;ABL1;SYK;LYN GO:2001225| regulation of chloride transport ABCB1;CA2;CA7 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2E1;SQLE;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0035556| intracellular signal transduction SRC;PRKCB;BCR;PRKCA;SYK;LYN;CAMK2G GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1;CYP1A1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CSNK2A1 GO:0018105| peptidyl-serine phosphorylation PRKCB;SRC;PRKCA;SYK;CDK2;PRKACA;CAMK2G GO:0009615| response to virus CYP1A1;SRC GO:1901796| CDK2;CSNK2A1 GO:0007155| cell adhesion HCK;SRC;ABL1;PRKCA GO:0045087| innate immune response ABL1;SRC;HCK;SYK;LYN GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0032496| response to lipopolysaccharide CYP1A1;BCR GO:0045931| positive regulation of mitotic cell cycle PRKCA;ABL1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1;CYP2E1 GO:0018108| peptidyl-tyrosine phosphorylation SYK;LYN;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;PRKCB GO:0043393| regulation of protein binding PRKACA;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;PRKACA;LYN;SYK GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;SYK;LYN;CAMK2G GO:0050853| B cell receptor signaling pathway PRKCB;ABL1;LYN;SYK GO:0007049| cell cycle CDK2;CSNK2A1;SRC GO:0010033| response to organic substance CDK2;CYP1A1;CA2;SQLE GO:0007411| axon guidance PRKCA;SRC GO:0009636| response to toxin LYN;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;LYN GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0007596| blood coagulation LYN;PRKACA GO:0008283| cell proliferation SYK;CYP1A1;SRC GO:0038095| SYK;LYN GO:0000187| activation of MAPK activity SYK;MAP3K2;MAP2K2;MAP2K1 GO:0006915| apoptotic process PRKCA;ABL1;PRKCB;CSNK2A1 GO:0055085| transmembrane transport SLC22A6;SLC22A11;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade PRKCA;ABL1;MAP2K1;MAP2K2;SRC GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CSNK2A1 GO:0007257| activation of JUN kinase activity MAP3K2;SYK GO:0045785| positive regulation of cell adhesion SRC;PRKCA GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;PRKACA GO:0050861| positive regulation of B cell receptor signaling pathway PRKCB;LYN GO:0050715| positive regulation of cytokine secretion SYK;SRC GO:0006979| response to oxidative stress ABL1;CA3 GO:0002376| immune system process PRKCB;SRC;HCK;SYK;LYN GO:0070372| regulation of ERK1 and ERK2 cascade SYK;LYN GO:0070555| response to interleukin-1 SRC;PRKCA GO:0051090| regulation of sequence-specific DNA binding transcription factor activity SYK;HCK GO:0007165| signal transduction CSNK2A1;LYN;MAP2K1;BCR;PRKCB;SRC GO:0017144| drug metabolic process CYP3A4;CYP1A1;CYP2E1;CYP2C8 GO:0097267| CYP2C8;CYP1A1 GO:0034605| cellular response to heat LYN;PRKACA GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway SYK;LYN;HCK GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A1;CYP2C8 GO:0030335| positive regulation of cell migration LYN;PRKCA GO:0016310| phosphorylation CSNK2A1;MAP3K2;LYN;CDK2;SYK;PRKACA;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;PRKCB;PRKCA;ABL1 GO:0050764| regulation of phagocytosis HCK;SYK GO:0010595| positive regulation of endothelial cell migration ABL1;PRKCA GO:0030168| platelet activation SYK;LYN;PRKCA;SRC;PRKCB GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC;SYK GO:0006468| protein phosphorylation ABL1;PRKCA;PRKCB;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;PRKACA;CDK2;LYN;SYK;CSNK2A1;MAP3K2 4529:[DB06616 DB03349] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide BCR;SRC;PDE4B;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;HINT1 GO:0050900| leukocyte migration SRC;PDE4B;LYN GO:0007165| signal transduction PDE4B;SRC;BCR;MAP2K1;HINT1;LYN GO:0006915| apoptotic process ABL1;HINT1 4530:[DB06616 DB02872] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways GO:0031648| protein destabilization SRC;MDM2 GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;MDM2 GO:0071456| cellular response to hypoxia SRC;MDM2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;MDM2 GO:0070301| cellular response to hydrogen peroxide MDM2;ABL1 GO:0071375| cellular response to peptide hormone stimulus MDM2;SRC GO:0010628| positive regulation of gene expression MDM2;SRC;MAP2K1 GO:0045184| establishment of protein localization MDM2;ABL1 GO:0009636| response to toxin LYN;MDM2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MDM2;CDK2 GO:0007507| heart development MDM2;MAP2K1 GO:0043066| negative regulation of apoptotic process MDM2;HCK;SRC GO:1901796| CDK2;MDM2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;MDM2;HCK GO:0045931| positive regulation of mitotic cell cycle MDM2;ABL1 GO:0016032| viral reproduction SRC;HCK;MDM2;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;SRC GO:0042493| response to drug LYN;MDM2;ABCB1;SRC GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;MDM2 4531:[DB06616 DB08822] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08822|Azilsartan medoxomil AGTR1 common genes common pathways GO:0042127| regulation of cell proliferation AGTR1;ABL1;SRC GO:0050727| regulation of inflammatory response LYN;HCK;AGTR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AGTR1 GO:0007165| signal transduction AGTR1;BCR;SRC;MAP2K1;LYN 4532:[DB06616 DB02837] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02837|O4-Sulfonylgalactose MBL2 common genes common pathways GO:0050766| positive regulation of phagocytosis MBL2;BCR GO:0006979| response to oxidative stress ABL1;MBL2 GO:0002376| immune system process SRC;HCK;LYN;MBL2 GO:0045087| innate immune response ABL1;HCK;SRC;LYN;MBL2 4533:[DB06616 DB05418] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05418|GW 597599 TACR1 common genes common pathways GO:0051602| response to electrical stimulus SRC;TACR1 GO:0006954| inflammatory response HCK;TACR1;LYN GO:0010634| positive regulation of epithelial cell migration TACR1;SRC GO:0014070| response to organic cyclic compound LYN;TACR1 GO:0051496| positive regulation of stress fiber assembly TACR1;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TACR1 GO:0009725| response to hormone stimulus TACR1;LYN GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;TACR1 4534:[DB06616 DB01080] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0042493| response to drug LYN;ABAT;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;GABBR1 GO:0055085| transmembrane transport ABCB1;SLC36A1 4535:[DB06616 DB05218] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05218|PN0621 TNF common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ABL1;MAP2K2;SRC;MAP2K1 GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;TNF GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNF GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0010033| response to organic substance CDK2;TNF GO:0010628| positive regulation of gene expression SRC;MAP2K1;TNF GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0051222| positive regulation of protein transport TNF;SRC GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0050900| leukocyte migration TNF;LYN;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;TNF GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;TNF GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;TNF;CDK2 GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0006954| inflammatory response HCK;LYN;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF GO:0007275| multicellular organismal development TNF;CDK2;CAMK2G GO:0042127| regulation of cell proliferation TNF;ABL1;SRC GO:0001932| regulation of protein phosphorylation TNF;LYN;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0009615| response to virus TNF;SRC GO:0071222| cellular response to lipopolysaccharide TNF;BCR;SRC;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;TNF GO:0050727| regulation of inflammatory response HCK;LYN;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;TNF;HCK 4536:[DB06616 DB07976] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0042493| response to drug LYN;DHODH;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0043065| positive regulation of apoptotic process ABL1;DHODH;SRC 4537:[DB06616 DB03791] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03791|(3-{3-[[2-Chloro-3-(Trifluoromethyl)Benzyl](2,2-Diphenylethyl)Amino]Propoxy}Phenyl)Acetic Acid NR1H2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1H2;MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1H2 GO:0010629| negative regulation of gene expression NR1H2;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H2;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent NR1H2;SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1;NR1H2 4538:[DB06616 DB02499] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02499|Dinor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide ABL1;ARG1 GO:0043200| response to amino acid stimulus ARG1;LYN GO:0002376| immune system process ARG1;HCK;SRC;LYN GO:0043434| response to peptide hormone stimulus ARG1;LYN GO:0002250| adaptive immune response LYN;ARG1 GO:0042493| response to drug LYN;ARG1;ABCB1;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ARG1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;ARG1 GO:0045087| innate immune response LYN;HCK;SRC;ARG1;ABL1 GO:0032496| response to lipopolysaccharide ARG1;BCR GO:0048678| response to axon injury ARG1;LYN 4539:[DB06616 DB02109] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02109|Hadacidin purA;ADSSL1 common genes common pathways GO:0002376| immune system process ADSSL1;SRC;HCK;LYN 4540:[DB06616 DB03415] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;ACADM GO:0006629| lipid metabolic process CYP3A4;ACADM 4541:[DB06616 DB05408] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05408|Emricasan CASP1;CASP3;CASP7 common genes common pathways GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0042493| response to drug CASP3;SRC;ABCB1;LYN GO:0010506| regulation of autophagy CASP1;ABL1 GO:0001782| B cell homeostasis LYN;CASP3 GO:0030218| erythrocyte differentiation CASP3;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;ABL1 GO:0032496| response to lipopolysaccharide CASP1;CASP3;BCR GO:0007507| heart development CASP3;MAP2K1 GO:0042981| regulation of apoptotic process MAP3K2;CASP1;MAP2K2;MAP2K1 GO:0051882| mitochondrial depolarization ABL1;CASP1 GO:0071260| cellular response to mechanical stimulus MAP3K2;CASP1 GO:0006974| response to DNA damage stimulus LYN;CDK2;CASP3;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;CASP3 GO:0050727| regulation of inflammatory response HCK;LYN;CASP1 GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0071222| cellular response to lipopolysaccharide CASP1;SRC;BCR;ABL1 GO:0035556| intracellular signal transduction SRC;BCR;CASP3;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;CASP3 GO:0006915| apoptotic process ABL1;CASP3;CASP7;CASP1 GO:0030216| keratinocyte differentiation MAP2K1;CASP3 GO:0030182| neuron differentiation ABL1;MAP2K1;CASP3 GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0010033| response to organic substance CDK2;CASP3 GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0007165| signal transduction LYN;CASP1;MAP2K1;BCR;SRC GO:0050715| positive regulation of cytokine secretion CASP1;SRC 4542:[DB06616 DB06999] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways GO:0000165| MAPKKK cascade MAP2K2;BRAF;MAP2K1;CAMK2G GO:0060324| face development MAP2K1;BRAF GO:0048679| regulation of axon regeneration MAP2K1;BRAF GO:0042127| regulation of cell proliferation SRC;BRAF;ABL1 GO:0050772| positive regulation of axonogenesis BRAF;MAP2K1 GO:0035556| intracellular signal transduction BCR;BRAF;SRC;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process BRAF;SRC;HCK GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;BRAF GO:0045580| regulation of T cell differentiation BRAF;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;BRAF GO:0051496| positive regulation of stress fiber assembly BRAF;ABL1 GO:0046632| alpha-beta T cell differentiation BRAF;ABL1 GO:0010628| positive regulation of gene expression BRAF;SRC;MAP2K1 GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;BCR;BRAF;MAP2K2;HCK;MAP2K1 GO:0030154| cell differentiation CAMK2G;HCK;BRAF GO:0000186| activation of MAPKK activity MAP3K2;BRAF GO:0016310| phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BRAF;BCR GO:0043434| response to peptide hormone stimulus BRAF;LYN GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;BRAF GO:0048538| thymus development MAP2K1;BRAF;ABL1 GO:1900026| BRAF;ABL1 GO:0030878| thyroid gland development MAP2K1;BRAF 4543:[DB06616 DB07435] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07435|1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE POLK;polA common genes common pathways GO:0006260| DNA replication POLK;CDK2 GO:0006281| DNA repair ABL1;POLK;CDK2 GO:0006974| response to DNA damage stimulus CDK2;LYN;POLK;ABL1 4544:[DB06616 DB14018] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14018|Bromotheophylline CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug LYN;CYP1A2;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 4545:[DB06616 DB00405] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00405|Dexbrompheniramine HRH1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;HRH1;LYN GO:0006954| inflammatory response HRH1;LYN;HCK GO:0043114| regulation of vascular permeability HRH1;SRC;BCR 4546:[DB06616 DB04883] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04883|Darusentan EDNRA common genes common pathways GO:0007165| signal transduction LYN;EDNRA;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;EDNRA GO:0008283| cell proliferation EDNRA;SRC GO:0007507| heart development EDNRA;MAP2K1 4547:[DB06616 DB00878] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00878|Chlorhexidine HNMT;cat common genes common pathways GO:0007420| brain development BCR;HNMT 4548:[DB06616 DB09265] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09265|Lixisenatide GLP1R common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;GLP1R GO:0007165| signal transduction GLP1R;LYN;SRC;BCR;MAP2K1 4549:[DB06616 DB07621] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2A6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2C8 4550:[DB06616 DB11429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11429|Mibolerone AR common genes common pathways GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation SRC;AR GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction LYN;AR;MAP2K1;BCR;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K2;SRC;MAP2K1;AR GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0051259| protein oligomerization AR;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0042327| positive regulation of phosphorylation LYN;AR GO:0008284| positive regulation of cell proliferation AR;HCK;LYN;CDK2 4551:[DB06616 DB05466] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05466|R673 TACR1 common genes common pathways GO:0010634| positive regulation of epithelial cell migration SRC;TACR1 GO:0051602| response to electrical stimulus SRC;TACR1 GO:0006954| inflammatory response LYN;TACR1;HCK GO:0007165| signal transduction BCR;SRC;MAP2K1;TACR1;LYN GO:0009725| response to hormone stimulus TACR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration TACR1;ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1;TACR1 GO:0014070| response to organic cyclic compound LYN;TACR1 4552:[DB06616 DB05752] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1;CHRM2 GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0009615| response to virus SRC;CHRM2 GO:0007165| signal transduction CHRM3;CHRM5;CHRM2;LYN;CHRM1;CHRM4;MAP2K1;SRC;BCR GO:0008283| cell proliferation SRC;CHRM4;CHRM1;CHRM5;CHRM3 GO:0006464| protein modification process ABL1;CHRM3;CHRM1 4553:[DB06616 DB07804] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07804|5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation LYN;F10 4554:[DB06616 DB04805] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04805|Virginiamycin S1 RPL37 common genes common pathways 4555:[DB06616 DB06460] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;EDNRB GO:0008284| positive regulation of cell proliferation HCK;EDNRB;LYN;CDK2 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;EDNRB GO:0007399| nervous system development EDNRB;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;EDNRB GO:0007507| heart development EDNRA;MAP2K1 GO:0032496| response to lipopolysaccharide EDNRB;BCR GO:0001934| positive regulation of protein phosphorylation LYN;EDNRB;ABL1 GO:0007165| signal transduction EDNRB;SRC;BCR;MAP2K1;EDNRA;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;EDNRB;EDNRA GO:0014070| response to organic cyclic compound LYN;EDNRB GO:0008283| cell proliferation EDNRA;SRC 4556:[DB06616 DB01019] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;LYN;CHRM3;SRC;BCR;CHRM4;MAP2K1 GO:0008283| cell proliferation CHRM4;SRC;CHRM3;CHRM1 GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;CHRM1;HCK GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM3;CHRM2;CHRM1;CAMK2G 4557:[DB06616 DB13800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CALM1;CAMK2G GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0002576| platelet degranulation CALM1;LYN GO:0055085| transmembrane transport CALM1;ABCB1 GO:0038095| CALM1;LYN GO:0010033| response to organic substance CDK2;CASQ1 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1;CALM1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol CASQ1;ABL1 4558:[DB06616 DB04527] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways GO:0045087| innate immune response MASP2;ABL1;HCK;SRC;LYN GO:0002376| immune system process SRC;HCK;MASP2;LYN 4559:[DB06616 DB08491] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08491|N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE MMP1 common genes common pathways GO:0050900| leukocyte migration MMP1;SRC;LYN GO:0016032| viral reproduction LYN;HCK;SRC;MMP1 4560:[DB06616 DB08613] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0070555| response to interleukin-1 HDAC4;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;HDAC4 GO:0014911| positive regulation of smooth muscle cell migration HDAC4;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;HDAC4 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HDAC4;HCK GO:0071260| cellular response to mechanical stimulus HDAC4;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC4;CDK2 GO:0007399| nervous system development HDAC4;CAMK2G GO:0043393| regulation of protein binding HDAC4;SRC GO:0006954| inflammatory response HCK;LYN;HDAC4 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;HDAC4;CDK2 GO:0042493| response to drug ABCB1;SRC;LYN;HDAC4 GO:0006355| regulation of transcription, DNA-dependent ABL1;HDAC4 4561:[DB06616 DB01496] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;CDK2;LYN GO:0006281| DNA repair ABL1;CHRNA4;CDK2 GO:0006816| calcium ion transport CAMK2G;CHRNA7;CHRNA4 GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7;ABL1 GO:0006979| response to oxidative stress ABL1;CHRNA4 GO:0007420| brain development GABRA5;BCR GO:0007165| signal transduction CHRNA7;BCR;CHRNA4;GRIA2;SRC;MAP2K1;GABRA6;LYN;GABRA5 GO:0007417| central nervous system development LYN;GABRA4;SRC GO:0006810| transport GABRA5;GABRA3;GABRA4;GABRA6;GRIK2;GABRA1;ABCB1 GO:0000187| activation of MAPK activity CHRNA7;MAP2K2;MAP2K1;MAP3K2 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;CHRNA7;MAP2K2;SRC;MAP2K1 4562:[DB06616 DB05194] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways GO:0097028| dendritic cell differentiation CSF2;LYN GO:0045892| negative regulation of transcription, DNA-dependent CSF2;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;CSF2 GO:0065009| regulation of molecular function CSF2;CSF2RA;CAMK2G GO:0071803| positive regulation of podosome assembly CSF2;SRC GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CSF2RA;CSF2;CAMK2G GO:0019221| cytokine-mediated signaling pathway HCK;CSF2RA GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein CSF2;LYN GO:0018108| peptidyl-tyrosine phosphorylation CSF2;SRC;CSF2RA;BCR;MAP2K2;HCK;MAP2K1;ABL1;LYN GO:0042127| regulation of cell proliferation ABL1;SRC;CSF2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;CSF2;HCK GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;CSF2;SRC 4563:[DB06616 DB11699] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11699|Tropisetron HTR3A common genes common pathways GO:0007165| signal transduction SRC;BCR;HTR3A;MAP2K1;LYN 4564:[DB06616 DB04948] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0009636| response to toxin HTR1D;LYN GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0008283| cell proliferation HTR1A;SRC GO:0006915| apoptotic process ADRA1A;ABL1 GO:0006855| drug transmembrane transport SLC47A1;ABCB1;ABCB5 GO:0055085| transmembrane transport SLC47A1;ABCB1;ABCB5 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;ADRA1A;MAP2K2;ABL1;HTR2C GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0097267| CYP2C19;CYP2C8;CYP1A2 GO:0007165| signal transduction ADRA2A;HTR2C;HTR7;MAP2K1;ADRA1A;SRC;BCR;LYN;HTR1A;HTR1D GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C8;CYP2C19 GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0030168| platelet activation ADRA2A;SRC;LYN GO:0030154| cell differentiation CAMK2G;HCK;ABCB5 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8;CYP2C19 GO:0042493| response to drug LYN;CYP1A2;HTR2C;ABCB1;SRC;ADRA1A GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4 GO:0035556| intracellular signal transduction BCR;SRC;ADRA1A;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;LYN;CDK2;HTR1A GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0042737| drug catabolic process CYP2D6;CYP1A2;CYP3A4 4565:[DB06616 DB07384] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07384|1-ACETYL-2-CARBOXYPIPERIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 4566:[DB06616 DB13994] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways GO:0006810| transport ABCB1;GABRA3 4567:[DB06616 DB07712] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07712|3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;NCOA2 GO:0060065| uterus development ESR1;SRC GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;ABL1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0007165| signal transduction LYN;ESR1;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC 4568:[DB06616 DB07798] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07798|(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 4569:[DB06616 DB00414] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways GO:0055114| oxidation-reduction process CBR1;CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0002576| platelet degranulation ALB;LYN GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CBR1;CYP2C8 GO:0006813| potassium ion transport KCNJ1;CDK2 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 4570:[DB06616 DB02670] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SMARCA5;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 4571:[DB06616 DB02755] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02755|1-3 Sugar Ring of Pentamannosyl 6-Phosphate M6PR common genes common pathways GO:0007165| signal transduction LYN;M6PR;SRC;BCR;MAP2K1 4572:[DB06616 DB00565] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00565|Cisatracurium CHRNA2 common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;CHRNA2;BCR;SRC 4573:[DB06616 DB06925] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways GO:0050900| leukocyte migration LCK;SRC;LYN GO:0038083| LYN;ABL1;SRC;LCK;HCK GO:0042493| response to drug LYN;SRC;ABCB1;LCK GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC GO:0016032| viral reproduction SRC;LCK;HCK;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;LCK;SRC;MAP2K2;BCR;LYN GO:0042127| regulation of cell proliferation LCK;SRC;ABL1 GO:0045087| innate immune response ABL1;LCK;HCK;SRC;LYN GO:0016477| cell migration LCK;SRC GO:0006470| protein dephosphorylation CAMK2G;LCK GO:0050690| regulation of defense response to virus by virus HCK;LCK GO:0050853| B cell receptor signaling pathway ABL1;LCK;LYN GO:0030168| platelet activation LYN;LCK;SRC GO:0006468| protein phosphorylation HCK;MAP2K1;LCK;SRC;MAP2K2;BCR;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;LCK;HCK GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;LCK;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0031295| T cell costimulation LCK;SRC;LYN GO:0030097| hemopoiesis LYN;LCK 4574:[DB06616 DB08502] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08502|Capravirine CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 4575:[DB06616 DB05685] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05685|FX06 CDH5 common genes common pathways GO:0007155| cell adhesion ABL1;CDH5;HCK;SRC GO:0050728| negative regulation of inflammatory response BCR;CDH5 GO:0034332| adherens junction organization SRC;CDH5 GO:0098609| CDH5;SRC GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;CDH5 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 4576:[DB06616 DB00494] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound LYN;COMT GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4;UGT1A9 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0042493| response to drug SRC;ABCB1;COMT;LYN GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0032496| response to lipopolysaccharide BCR;COMT GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process UGT1A9;CYP3A4;CYP2D6;CYP2C8 4577:[DB06616 DB01548] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;LYN;MAP2K1;BCR;SRC;OPRK1;TRIM13 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K1;MAP2K2;SRC;ABL1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0045087| innate immune response ABL1;TRIM13;SRC;HCK;LYN GO:0071222| cellular response to lipopolysaccharide BCR;SRC;OPRK1;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TRIM13 GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0010629| negative regulation of gene expression OPRD1;MAP2K2;MAP2K1 4578:[DB06616 DB11256] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC46A1 GO:0071732| cellular response to nitric oxide MTR;CDK2 GO:0007399| nervous system development MTR;CAMK2G GO:0048678| response to axon injury MTR;LYN 4579:[DB06616 DB00315] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0008283| cell proliferation HTR1A;SRC GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009636| response to toxin HTR1D;LYN GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;HTR1B;BCR;HTR1F;HTR1D;LYN;HTR1A GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug LYN;CYP1A2;ABCB1;HTR1B;SRC GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;HTR1A GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 4580:[DB06616 DB11064] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0051259| protein oligomerization CAMK2G;AR GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0008284| positive regulation of cell proliferation HCK;AR;CDK2;LYN GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0060065| uterus development SRC;ESR1 GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;AR GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2;PGR GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1;AR;PGR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;AR;MAP2K2;SRC;MAP2K1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0050847| progesterone receptor signaling pathway SRC;PGR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction ESR1;LYN;BCR;PGR;SRC;MAP2K1;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN 4581:[DB06616 DB03152] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03152|B-2-Octylglucoside polA;aqpZ;TGM3;aqpZ;petB;petA;RHO common genes common pathways GO:0006468| protein phosphorylation MAP3K2;RHO;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0007165| signal transduction RHO;LYN;SRC;BCR;MAP2K1 GO:0030216| keratinocyte differentiation TGM3;MAP2K1 GO:0006464| protein modification process ABL1;TGM3 4582:[DB06616 DB05044] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05044|PSN357 PYGL common genes common pathways 4583:[DB06616 DB03926] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03926|5-Alpha-Androstane-3-Beta,17-Alpha-Diol SHBG common genes common pathways 4584:[DB06616 DB07720] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0006281| DNA repair CDK2;CHRNA4;ABL1 GO:0007399| nervous system development CAMK2G;CHRNA3 GO:0008284| positive regulation of cell proliferation HCK;CHRNA7;LYN;CDK2 GO:0006816| calcium ion transport CHRNA4;CHRNA7;CHRNB2;CAMK2G GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7;ABL1 GO:0007165| signal transduction CHRNA2;MAP2K1;SRC;CHRNA3;CHRNA4;BCR;CHRNA7;CHRNB2;CHRNB4;LYN;CHRFAM7A GO:0006979| response to oxidative stress ABL1;CHRNA4 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;CHRNA7;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;ABL1;MAP2K1;MAP2K2;SRC 4585:[DB06616 DB07694] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 4586:[DB06616 DB05201] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05201|V24343 CNR1 common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;SRC;ABL1 GO:0032496| response to lipopolysaccharide BCR;CNR1 GO:0010976| positive regulation of neuron projection development CNR1;LYN GO:0007165| signal transduction MAP2K1;BCR;SRC;CNR1;LYN 4587:[DB06616 DB05451] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05451|P54 NFKB2;NFKB1 common genes common pathways GO:0006915| apoptotic process NFKB1;ABL1 GO:0038095| LYN;NFKB1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NFKB1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;NFKB1 GO:0007165| signal transduction NFKB1;MAP2K1;BCR;SRC;LYN;NFKB2 GO:0048536| spleen development NFKB2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;SRC;NFKB1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;ABL1;NFKB2 GO:0010629| negative regulation of gene expression NFKB1;MAP2K2;MAP2K1 GO:0006954| inflammatory response LYN;NFKB2;HCK;NFKB1 GO:0050728| negative regulation of inflammatory response NFKB1;BCR GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;NFKB1;LYN GO:0032496| response to lipopolysaccharide NFKB2;BCR GO:0071260| cellular response to mechanical stimulus MAP3K2;NFKB1 GO:0045087| innate immune response NFKB1;ABL1;HCK;SRC;NFKB2;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB2;CDK2;NFKB1 GO:0043066| negative regulation of apoptotic process HCK;SRC;NFKB1 GO:0071222| cellular response to lipopolysaccharide ABL1;NFKB1;SRC;BCR 4588:[DB06616 DB03566] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process TXNRD1;CYP2C8;CYP3A4 GO:0034599| cellular response to oxidative stress TXNRD1;ABL1 GO:0008283| cell proliferation SRC;TXNRD1 GO:0055085| transmembrane transport ABCB1;SLC22A4;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;ADRB2 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0045453| bone resorption SRC;ADRB2 GO:0007165| signal transduction LYN;ADRB2;BCR;ADRB1;SRC;MAP2K1;TXNRD1 4589:[DB06616 DB09331] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09331|Daratumumab CD38 common genes common pathways GO:0042493| response to drug CD38;LYN;ABCB1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CD38;CDK2;MAP3K2 GO:0043066| negative regulation of apoptotic process CD38;SRC;HCK GO:0050853| B cell receptor signaling pathway CD38;LYN;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;CD38 GO:0007165| signal transduction CD38;LYN;BCR;SRC;MAP2K1 GO:0009725| response to hormone stimulus LYN;CD38 GO:0070555| response to interleukin-1 CD38;SRC GO:0007204| elevation of cytosolic calcium ion concentration CD38;ABL1 4590:[DB06616 DB01337] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01337|Pancuronium CHRNA2;CHRM2;CHRM3;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM3;CHRM2;CAMK2G GO:0042493| response to drug LYN;BCHE;SRC;ABCB1 GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRNA2;CHRM3;LYN;CHRM2 GO:0006464| protein modification process ABL1;CHRM3 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0008283| cell proliferation CHRM3;SRC GO:0055085| transmembrane transport ABCB1;SLC22A2;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2 4591:[DB06616 DB06111] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06111|AB192 MPO common genes common pathways GO:0006979| response to oxidative stress ABL1;MPO GO:0032496| response to lipopolysaccharide MPO;BCR GO:0043066| negative regulation of apoptotic process MPO;SRC;HCK GO:0009612| response to mechanical stimulus MPO;SRC GO:0055114| oxidation-reduction process CYP3A4;MPO;CYP2C8 4592:[DB06616 DB04783] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04783|Sphinxolide B ACTA1 common genes common pathways GO:0009612| response to mechanical stimulus SRC;ACTA1 GO:0010628| positive regulation of gene expression MAP2K1;ACTA1;SRC 4593:[DB06616 DB01977] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01977|6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC GO:0006935| chemotaxis PLAU;MAP2K1 GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0007596| blood coagulation PLAU;LYN GO:0030335| positive regulation of cell migration PLAU;LYN GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;PLAU 4594:[DB06616 DB04915] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04915|Idronoxil ENOX2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ENOX2;CYP2C8 4595:[DB06616 DB04997] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04997|ATL1102 ITGA4 common genes common pathways GO:0050900| leukocyte migration ITGA4;SRC;LYN GO:0034446| substrate adhesion-dependent cell spreading ITGA4;SRC;ABL1 GO:0007155| cell adhesion SRC;ITGA4;HCK;ABL1 GO:0007229| integrin-mediated signaling pathway ABL1;HCK;ITGA4;SRC 4596:[DB06616 DB05091] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05091|M0002 AVPR2 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;AVPR2;SRC GO:0007165| signal transduction LYN;BCR;SRC;AVPR2;MAP2K1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;AVPR2 4597:[DB06616 DB00704] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00704|Naltrexone OPRD1;OPRM1;OPRK1;SIGMAR1;UGT1A1 common genes common pathways GO:0042493| response to drug ABCB1;SRC;UGT1A1;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;OPRD1 GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide BCR;UGT1A1;OPRM1 GO:0007399| nervous system development CAMK2G;SIGMAR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;SRC;BCR GO:0032868| response to insulin stimulus OPRK1;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;OPRM1 GO:0014070| response to organic cyclic compound LYN;UGT1A1 GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN GO:0010033| response to organic substance CDK2;UGT1A1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2C8 GO:0007165| signal transduction OPRK1;MAP2K1;SRC;BCR;LYN;OPRD1;OPRM1 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2C8 4598:[DB06616 DB07334] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07334|N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE KDR common genes common pathways GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;KDR;HCK;LYN GO:0007275| multicellular organismal development CAMK2G;CDK2;KDR GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process KDR;HCK;SRC GO:0008284| positive regulation of cell proliferation KDR;HCK;LYN;CDK2 GO:0008360| regulation of cell shape KDR;HCK GO:0010629| negative regulation of gene expression KDR;MAP2K1;MAP2K2 GO:0038083| LYN;ABL1;SRC;HCK;KDR GO:0001934| positive regulation of protein phosphorylation KDR;ABL1;LYN GO:0016032| viral reproduction KDR;HCK;SRC;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;KDR GO:0030335| positive regulation of cell migration LYN;KDR GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;KDR;HCK;CAMK2G;LYN;CDK2;MAP3K2 GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;KDR;HCK;MAP2K2;BCR;SRC;ABL1 GO:0030154| cell differentiation HCK;KDR;CAMK2G GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;KDR;MAP2K1;ABL1 GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;SRC;BCR;HCK;KDR 4599:[DB06616 DB08172] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0043065| positive regulation of apoptotic process SRC;DHODH;ABL1 GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0042493| response to drug LYN;DHODH;ABCB1;SRC 4600:[DB06616 DB00790] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;SFRP4;LYN;MAP2K1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;SFRP4 GO:0010628| positive regulation of gene expression SRC;MAP2K1;SFRP4 GO:0055085| transmembrane transport ABCB1;SLC15A2;SLC15A1 GO:0009725| response to hormone stimulus SFRP4;LYN GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0030154| cell differentiation SFRP4;CAMK2G;HCK GO:0042493| response to drug SRC;ABCB1;BCHE;LYN GO:0043065| positive regulation of apoptotic process SFRP4;SRC;ABL1 GO:0007275| multicellular organismal development CDK2;SFRP4;CAMK2G 4601:[DB06616 DB01962] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes SRC;HCK common pathways GO:0071456| cellular response to hypoxia SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;KIT;MAP2K1;SRC;BCR;MAP2K2 GO:0030154| cell differentiation HCK;CAMK2G GO:0048477| oogenesis SRC GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0043299| leukocyte degranulation HCK GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;KIT;HCK;ABL1 GO:0050764| regulation of phagocytosis HCK GO:0031295| T cell costimulation SRC;LYN GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;KIT;HCK GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;KIT;SRC GO:0098609| SRC GO:0030335| positive regulation of cell migration KIT;LYN GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0006887| exocytosis HCK GO:0007165| signal transduction KIT;MAP2K1;SRC;BCR;LYN GO:0070542| response to fatty acid SRC GO:0030097| hemopoiesis KIT;LYN GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0030900| forebrain development SRC GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK GO:1900182| SRC GO:0060333| interferon-gamma-mediated signaling pathway HCK;CAMK2G GO:0032463| negative regulation of protein homooligomerization SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process SRC;HCK;LYN GO:0045453| bone resorption SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0002522| leukocyte migration involved in immune response HCK GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0002758| innate immune response-activating signal transduction HCK GO:0010954| positive regulation of protein processing SRC GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;KIT;MAP3K2 GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0050690| regulation of defense response to virus by virus HCK GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0043406| positive regulation of MAP kinase activity KIT;SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation ABL1;HCK;KIT;SRC;BCR;LYN;CAMK2G GO:0051895| negative regulation of focal adhesion assembly SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;KIT;MAP2K1 GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0086098| SRC GO:0045728| respiratory burst after phagocytosis HCK GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;KIT GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein KIT;LYN GO:0007498| mesoderm development HCK GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation ABL1;SRC;KIT GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0030838| positive regulation of actin filament polymerization HCK GO:0045087| innate immune response LYN;ABL1;SRC;HCK GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0032148| activation of protein kinase B activity SRC GO:0008360| regulation of cell shape HCK;KIT GO:0010634| positive regulation of epithelial cell migration SRC GO:0033625| positive regulation of integrin activation SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0008284| positive regulation of cell proliferation HCK;KIT;CDK2;LYN GO:0050727| regulation of inflammatory response HCK;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction KIT;BCR;SRC;LYN;CAMK2G GO:0050900| leukocyte migration SRC;LYN GO:0034332| adherens junction organization SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0038083| SRC;HCK;ABL1;LYN GO:0042493| response to drug ABCB1;SRC;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0006909| phagocytosis ABL1;HCK GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0019221| cytokine-mediated signaling pathway HCK;KIT GO:0038128| SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| ABL1;SRC;HCK;LYN GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;KIT GO:0071803| positive regulation of podosome assembly SRC GO:0030218| erythrocyte differentiation KIT;LYN GO:0000165| MAPKKK cascade MAP2K2;KIT;MAP2K1;CAMK2G GO:0071498| cellular response to fluid shear stress SRC GO:0006954| inflammatory response HCK;KIT;LYN GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1 GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction SRC;HCK;LYN 4602:[DB06616 DB01835] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;NOS2 GO:0042127| regulation of cell proliferation NOS2;SRC;ABL1 GO:0032496| response to lipopolysaccharide BCR;NOS2 4603:[DB06616 DB03419] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DPYD;CYP2C8 GO:0016032| viral reproduction UCKL1;HCK;SRC;LYN GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;UCKL1 4604:[DB06616 DB01296] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0006928| cellular component movement IFNG;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC;MMP9 GO:0010628| positive regulation of gene expression TNF;IFNG;MAP2K1;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;IFNG GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0045892| negative regulation of transcription, DNA-dependent SRC;IFNG;TNF GO:0010033| response to organic substance CDK2;TNF GO:0048013| ephrin receptor signaling pathway SRC;LYN;MMP9 GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0006915| apoptotic process IFNG;ABL1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TNF;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;TNF GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0060333| interferon-gamma-mediated signaling pathway IFNG;HCK;CAMK2G GO:0048536| spleen development NFKB2;ABL1 GO:0007050| cell cycle arrest IFNG;ABL1;MAP2K1 GO:0051222| positive regulation of protein transport SRC;TNF GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19 GO:0097267| CYP2C8;CYP2C19 GO:0007165| signal transduction LYN;NFKB2;BCR;SRC;MAP2K1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19 GO:0030335| positive regulation of cell migration MMP9;LYN GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0006954| inflammatory response HCK;TNF;LYN;NFKB2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0002250| adaptive immune response LYN;IFNG GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0000165| MAPKKK cascade CAMK2G;TNF;MAP2K2;MAP2K1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MMP9;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;TNF;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;NFKB2 GO:0010629| negative regulation of gene expression TNF;IFNG;MAP2K1;MAP2K2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0042493| response to drug LYN;CYP2E1;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C19;CYP2C8 GO:0001934| positive regulation of protein phosphorylation IFNG;ABL1;LYN;TNF;MMP9 GO:0050900| leukocyte migration SRC;MMP9;TNF;LYN GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN;TNF GO:0043066| negative regulation of apoptotic process SRC;HCK;MMP9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0071222| cellular response to lipopolysaccharide TNF;ABL1;SRC;BCR GO:0009615| response to virus IFNG;SRC;TNF GO:0008284| positive regulation of cell proliferation CDK2;LYN;IFNG;HCK GO:0050727| regulation of inflammatory response HCK;LYN;TNF GO:0043065| positive regulation of apoptotic process SRC;ABL1;TNF;MMP9 GO:0045087| innate immune response ABL1;SRC;HCK;NFKB2;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;NFKB2;CDK2;TNF GO:0010634| positive regulation of epithelial cell migration IFNG;SRC GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0032496| response to lipopolysaccharide BCR;NFKB2 GO:0001932| regulation of protein phosphorylation MAP2K1;TNF;LYN GO:0042127| regulation of cell proliferation TNF;ABL1;SRC GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IFNG GO:0007275| multicellular organismal development TNF;CDK2;CAMK2G GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF 4605:[DB06616 DB12866] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport SLC22A8;ABCB1 4606:[DB06616 DB02974] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP2B6;CYP3A4 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2B6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2B6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 4607:[DB06616 DB01412] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0007399| nervous system development CAMK2G;ADORA1 GO:0043066| negative regulation of apoptotic process ADORA1;SRC;HCK GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C8 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;PDE4B;ABL1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;ADORA2A GO:0050900| leukocyte migration PDE4B;SRC;LYN GO:0006909| phagocytosis HCK;ABL1;ADORA1;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ABL1;ADORA2A GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP2E1;ADORA2A;LYN;CYP1A2;ABCB1;SRC GO:0051924| regulation of calcium ion transport CAMK2G;ADORA2A GO:0050728| negative regulation of inflammatory response ADORA1;ADORA2A;BCR GO:0006954| inflammatory response ADORA2A;LYN;ADORA1;HCK GO:0000186| activation of MAPKK activity ADORA1;MAP3K2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C8 GO:0007417| central nervous system development SRC;LYN;ADORA2A GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0007165| signal transduction ADORA1;LYN;ADORA2A;PDE4B;BCR;SRC;MAP2K1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0006915| apoptotic process ABL1;ADORA2A GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0007596| blood coagulation ADORA2A;LYN GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008285| negative regulation of cell proliferation ADORA2A;LYN;ADORA1;MAP2K1 GO:0009791| post-embryonic development CYP1A2;ABL1 4608:[DB06616 DB04674] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;AKR1C1;CYP3A4 GO:0007507| heart development MAP2K1;EDNRA GO:0055114| oxidation-reduction process CYP2C8;AKR1C1;CYP3A4 GO:0006810| transport TTR;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;ABL1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;EDNRA GO:0008283| cell proliferation SRC;EDNRA 4609:[DB06616 DB13150] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways GO:0019221| cytokine-mediated signaling pathway F3;HCK GO:0051897| positive regulation of protein kinase B signaling cascade F10;F3;SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F3;SRC GO:0007596| blood coagulation F9;F3;LYN;F10 GO:0030335| positive regulation of cell migration F3;F10;LYN 4610:[DB06616 DB04827] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G4A GO:0009612| response to mechanical stimulus MPO;SRC GO:0043066| negative regulation of apoptotic process MPO;SRC;HCK GO:0042127| regulation of cell proliferation PLA2G4A;SRC;ABL1 GO:0032496| response to lipopolysaccharide MPO;BCR GO:0055114| oxidation-reduction process CYP3A4;AOX1;CYP2C8;MPO GO:0017144| drug metabolic process CYP3A4;AOX1;CYP2C8 GO:0006979| response to oxidative stress ABL1;MPO 4611:[DB06616 DB00521] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K2;SRC;MAP2K1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction ADRB2;LYN;MAP2K1;ADRB1;SRC;BCR GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 4612:[DB06616 DB06842] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways GO:0050900| leukocyte migration PDE4D;LYN;SRC GO:0071222| cellular response to lipopolysaccharide PDE4D;ABL1;BCR;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;PDE4D;PDE4A;LYN 4613:[DB06616 DB05419] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05419|ADX-10061 CALY common genes common pathways GO:0006897| endocytosis ABL1;CALY 4614:[DB06616 DB07695] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 4615:[DB06616 DB07851] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK 4616:[DB06616 DB06782] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06782|Dimercaprol APP common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;APP;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;APP GO:1900272| APP;ABL1 GO:0006915| apoptotic process ABL1;APP GO:0000187| activation of MAPK activity APP;MAP3K2;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;APP GO:0031175| neuron projection development LYN;APP GO:0030900| forebrain development SRC;APP GO:0006979| response to oxidative stress APP;ABL1 GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;APP;CAMK2G;LYN;CDK2 GO:0007204| elevation of cytosolic calcium ion concentration APP;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade APP;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;APP;LYN GO:0001934| positive regulation of protein phosphorylation LYN;APP;ABL1 GO:0050885| neuromuscular process controlling balance BCR;ABL1;APP GO:1901216| ABL1;APP GO:0010629| negative regulation of gene expression APP;MAP2K1;MAP2K2 GO:0045087| innate immune response LYN;APP;ABL1;SRC;HCK GO:0007155| cell adhesion APP;SRC;HCK;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0007399| nervous system development APP;CAMK2G GO:0006897| endocytosis ABL1;APP GO:0042327| positive regulation of phosphorylation APP;LYN GO:0043065| positive regulation of apoptotic process APP;SRC;ABL1 GO:0002576| platelet degranulation APP;LYN GO:0043393| regulation of protein binding SRC;APP GO:0045931| positive regulation of mitotic cell cycle APP;ABL1 4617:[DB06616 DB00852] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0009791| post-embryonic development ABL1;ATF5 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0010628| positive regulation of gene expression ATF2;MAP2K1;SRC;SLC6A4;ATF3;TNF;ATF4 GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0034614| cellular response to reactive oxygen species JUN;FOS;SRC GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A;TNF GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;ATF5;JUN;LYN GO:0010033| response to organic substance SLC6A4;JUN;TNF;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent ATF5;SRC;ATF3;TNF;JUN GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0038095| NFATC1;FOS;LYN;JUN GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ATF3;LYN;ABL1 GO:0014070| response to organic cyclic compound FOS;LYN;JUN;ATF1;SLC6A3 GO:0009636| response to toxin FOS;LYN;SLC6A4 GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;JUN;ABL1;MAP2K1;SRC;ADRA1A;MAP2K2 GO:0055085| transmembrane transport SLC6A2;SLC6A4;SLC6A3;ABCB1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity TNF;MAP3K2;MAP2K2;MAP2K1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FOS;JUN GO:0002376| immune system process IL2;SRC;HCK;LYN GO:0045453| bone resorption ADRB2;SRC GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007420| brain development SLC6A4;BCR GO:0007165| signal transduction ATF6;ADRB2;LYN;ADRA2A;BCR;ADRA1A;SRC;ADRB1;MAP2K1 GO:0051222| positive regulation of protein transport TNF;SRC GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0051090| regulation of sequence-specific DNA binding transcription factor activity ATF2;HCK;JUN;FOS GO:1903351| ABL1;ATF4 GO:0065009| regulation of molecular function IL2;CAMK2G GO:0031668| cellular response to extracellular stimulus LYN;FOS GO:0043547| positive regulation of GTPase activity JUN;ADRB1;BCR GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration IL2;ABL1;ADRA1A GO:0006810| transport SLC6A2;ABCB1 GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0030168| platelet activation LYN;ADRA2A;SRC GO:0010976| positive regulation of neuron projection development LYN;ATF1 GO:0050728| negative regulation of inflammatory response IL2;BCR GO:0006954| inflammatory response LYN;FOS;TNF;HCK GO:0016032| viral reproduction HCK;ATF7;SRC;LYN GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;IL2;CAMK2G;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0002250| adaptive immune response LYN;IL2 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TNF GO:0042493| response to drug LYN;FOS;JUN;SLC6A2;SLC6A4;SLC6A3;SRC;ADRA1A;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ATF5;NFATC1;ATF1;ABL1;ATF7;ATF2;ATF6;ATF4;FOS;ATF3;JDP2;JUN GO:1901216| FOS;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;FOS;ATF4;CDK2;MAP3K2;JUN;NFATC1;ATF5;SRC;MAP2K2;MAP2K1 GO:0050900| leukocyte migration SRC;TNF;LYN GO:0001934| positive regulation of protein phosphorylation LYN;TNF;IL2;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4;MAOA GO:0050727| regulation of inflammatory response LYN;TNF;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;JUN;TNF;ATF4;ATF6 GO:0042542| response to hydrogen peroxide JUN;SRC GO:0009615| response to virus TNF;SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR;JUN GO:0071222| cellular response to lipopolysaccharide TNF;BCR;SRC;ABL1 GO:0008284| positive regulation of cell proliferation ATF3;CDK2;LYN;JUN;IL2;ADRA2A;HCK GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0035556| intracellular signal transduction BCR;ADRA1A;SRC;NFATC1;LYN;CAMK2G GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0009612| response to mechanical stimulus SRC;JUN;FOS GO:0043066| negative regulation of apoptotic process IL2;ATF5;HCK;SRC;JUN GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;LYN;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter JDP2;CDK2;TNF;ATF3;ATF7;ATF2 GO:0007155| cell adhesion ABL1;IL2;SRC;HCK GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0045597| positive regulation of cell differentiation MAP2K1;JUN GO:0010634| positive regulation of epithelial cell migration JUN;SRC GO:0007399| nervous system development FOS;CAMK2G GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006974| response to DNA damage stimulus LYN;CDK2;ABL1;ATF2 GO:0001932| regulation of protein phosphorylation TNF;LYN;MAP2K1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042127| regulation of cell proliferation JUN;TNF;SRC;ABL1 GO:0032496| response to lipopolysaccharide BCR;FOS;JUN GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0001933| negative regulation of protein phosphorylation LYN;IL2 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007265| Ras protein signal transduction CDK2;JUN;ADRA2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL2;LYN 4618:[DB06616 DB03083] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03083|IC261 CSNK1G2 common genes common pathways GO:0008360| regulation of cell shape HCK;CSNK1G2 GO:0006897| endocytosis ABL1;CSNK1G2 GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;CSNK1G2;SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CSNK1G2 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;CSNK1G2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CSNK1G2;CAMK2G;MAP3K2 GO:0046777| protein autophosphorylation CAMK2G;LYN;CSNK1G2;BCR;SRC;HCK;ABL1 4619:[DB06616 DB07765] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07765|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHRS4L1;CYP2C8 4620:[DB06616 DB02773] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways GO:0006979| response to oxidative stress ABL1;PTGS1 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGS1 GO:0006954| inflammatory response PTGS1;HCK;LYN 4621:[DB06616 DB05022] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0006974| response to DNA damage stimulus LYN;CDK2;TOP2A;ABL1 GO:0030900| forebrain development TOP2B;SRC 4622:[DB06616 DB06972] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06972|7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile ITGAL common genes common pathways GO:0006954| inflammatory response ITGAL;LYN;HCK GO:0006909| phagocytosis ABL1;HCK;ITGAL GO:0050900| leukocyte migration LYN;ITGAL;SRC GO:0007155| cell adhesion ABL1;HCK;SRC;ITGAL GO:0006928| cellular component movement MAP2K1;ITGAL GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ITGAL GO:0098609| SRC;ITGAL GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1;ITGAL 4623:[DB06616 DB00192] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00192|Indecainide SCN5A common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCB1 4624:[DB06616 DB00534] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0055114| oxidation-reduction process ALDH5A1;CYP2C8;CYP3A4 GO:0006810| transport SLC12A1;ABCB1 GO:0007417| central nervous system development SRC;ALDH5A1;LYN GO:0006813| potassium ion transport SLC12A1;CDK2 GO:0055085| transmembrane transport SLC12A1;ABCB1 GO:0009791| post-embryonic development ABL1;ALDH5A1 4625:[DB06616 DB02215] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02215|Furoyl-Leucine ADAM28 common genes common pathways 4626:[DB06616 DB08299] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways GO:0050900| leukocyte migration PDE4D;LYN;SRC;PDE4B GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PDE4B;PDE4D GO:0007165| signal transduction PDE4B;BCR;SRC;MAP2K1;LYN;PDE4A;PDE4D 4627:[DB06616 DB00229] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A6;SLC22A8;ABCB1 GO:0009636| response to toxin SLC22A8;LYN 4628:[DB06616 DB05210] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0016032| viral reproduction LYN;PIK3R1;SRC;HCK GO:0010976| positive regulation of neuron projection development LYN;MTOR GO:0051897| positive regulation of protein kinase B signaling cascade SRC;PIK3R1;MTOR;PIK3R2 GO:0038096| PIK3R2;LYN;HCK;SRC;PIK3R1;ABL1 GO:0038128| SRC;PIK3R1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;LYN;SRC;ABL1 GO:1901216| MTOR;ABL1 GO:0010506| regulation of autophagy ABL1;PIK3R2 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;PIK3R1;SRC GO:0001934| positive regulation of protein phosphorylation MTOR;LYN;ABL1 GO:0050900| leukocyte migration SRC;PIK3R1;PIK3R2;LYN GO:0048010| vascular endothelial growth factor receptor signaling pathway PIK3R2;PIK3R1;SRC GO:0043066| negative regulation of apoptotic process PRKDC;PIK3R1;HCK;SRC GO:0043065| positive regulation of apoptotic process PRKDC;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G;MTOR;PRKDC GO:0060252| positive regulation of glial cell proliferation LYN;MTOR GO:0006281| DNA repair CDK2;MTOR;PRKDC;ABL1 GO:0006974| response to DNA damage stimulus ABL1;PRKDC;LYN;CDK2 GO:0045087| innate immune response LYN;PRKDC;ABL1;HCK;SRC GO:0007507| heart development MAP2K1;PRKDC GO:0032148| activation of protein kinase B activity MTOR;SRC GO:0030838| positive regulation of actin filament polymerization HCK;MTOR GO:0001933| negative regulation of protein phosphorylation MTOR;PRKDC;LYN GO:0001932| regulation of protein phosphorylation LYN;MTOR;MAP2K1 GO:0010628| positive regulation of gene expression MTOR;MAP2K1;SRC GO:0009791| post-embryonic development ABL1;MTOR GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;MTOR;CAMK2G;LYN GO:0006464| protein modification process ABL1;PRKDC GO:0007411| axon guidance PIK3R1;SRC GO:0051496| positive regulation of stress fiber assembly MTOR;ABL1 GO:0043200| response to amino acid stimulus LYN;MTOR GO:0038095| PIK3R2;LYN;PIK3R1 GO:0008283| cell proliferation SRC;PRKDC GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis PRKDC;PIK3R1;ABL1 GO:0032868| response to insulin stimulus LYN;MTOR GO:0018107| peptidyl-threonine phosphorylation MAP2K1;MTOR;CAMK2G GO:1900034| CAMK2G;MTOR GO:2000773| negative regulation of cellular senescence PRKDC;ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1;MTOR GO:0002376| immune system process SRC;HCK;LYN;PRKDC GO:0048536| spleen development PRKDC;ABL1 GO:0048538| thymus development MAP2K1;ABL1;PRKDC GO:0031648| protein destabilization SRC;PRKDC GO:0007050| cell cycle arrest MAP2K1;ABL1;MTOR GO:0007420| brain development BCR;MTOR;PRKDC GO:0051056| regulation of small GTPase mediated signal transduction BCR;PIK3R2 GO:0007165| signal transduction LYN;MTOR;PIK3R2;PIK3R1;MAP2K1;SRC;BCR GO:0043547| positive regulation of GTPase activity BCR;PIK3R2 GO:0030335| positive regulation of cell migration LYN;PIK3R1 GO:0016310| phosphorylation PRKDC;MTOR;MAP3K2;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0031295| T cell costimulation LYN;PIK3R1;SRC GO:0030168| platelet activation SRC;PIK3R1;LYN GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;PIK3R1;ABL1;PRKDC;MTOR;MAP3K2;CAMK2G;CDK2;LYN GO:0071456| cellular response to hypoxia MTOR;SRC GO:0032869| cellular response to insulin stimulus PIK3R1;SRC;PIK3R2;PRKDC 4629:[DB06616 DB00963] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0042493| response to drug PTGS2;LYN;ABCB1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0070542| response to fatty acid PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia SRC;PTGS2 4630:[DB06616 DB07872] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07872|5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration F10;LYN 4631:[DB06616 DB00574] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00574|Fenfluramine SLC6A4;HTR2B;HTR2C;HTR2A;CYP2D6 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K2;SRC;MAP2K1;HTR2B;HTR2C;ABL1 GO:0055085| transmembrane transport SLC6A4;ABCB1 GO:0009636| response to toxin LYN;SLC6A4 GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;SRC GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;MAP2K1;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;HTR2B;MAP3K2;CAMK2G;LYN;CDK2 GO:0043547| positive regulation of GTPase activity BCR;HTR2B GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007420| brain development SLC6A4;BCR GO:0007165| signal transduction HTR2A;LYN;HTR2C;HTR2B;BCR;SRC;MAP2K1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0050715| positive regulation of cytokine secretion HTR2B;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042493| response to drug LYN;HTR2A;HTR2B;HTR2C;SLC6A4;SRC;ABCB1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;SRC;ABL1 GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K1;MAP2K2 GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0007507| heart development MAP2K1;HTR2B GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation HTR2B;HCK;LYN;CDK2;HTR2A GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0043066| negative regulation of apoptotic process HCK;SRC;HTR2B 4632:[DB06616 DB01819] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01819|Phosphoenolpyruvate aroG;kdsA;ENO3;PCK1;kdsA;SLCO2A1 common genes common pathways GO:0032496| response to lipopolysaccharide PCK1;BCR GO:0071300| cellular response to retinoic acid PCK1;LYN GO:0006629| lipid metabolic process PCK1;CYP3A4 GO:0042493| response to drug ABCB1;SRC;ENO3;LYN GO:0032869| cellular response to insulin stimulus PCK1;SRC GO:0071456| cellular response to hypoxia PCK1;SRC GO:0055085| transmembrane transport SLCO2A1;ABCB1 GO:0032868| response to insulin stimulus PCK1;LYN 4633:[DB06616 DB05305] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05305|Cintredekin Besudotox IL13 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;IL13 GO:0009612| response to mechanical stimulus IL13;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL13;LYN GO:0032496| response to lipopolysaccharide IL13;BCR GO:0006954| inflammatory response HCK;IL13;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol IL13;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis IL13;ABL1 4634:[DB06616 DB01871] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01871|[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways 4635:[DB06616 DB06138] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06138|IRL-1620 EDNRB common genes common pathways GO:0014070| response to organic cyclic compound EDNRB;LYN GO:0007204| elevation of cytosolic calcium ion concentration EDNRB;ABL1 GO:0007165| signal transduction LYN;EDNRB;BCR;SRC;MAP2K1 GO:0001934| positive regulation of protein phosphorylation EDNRB;ABL1;LYN GO:0032496| response to lipopolysaccharide BCR;EDNRB GO:0043066| negative regulation of apoptotic process EDNRB;HCK;SRC GO:0008284| positive regulation of cell proliferation EDNRB;HCK;CDK2;LYN GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;EDNRB GO:0007399| nervous system development EDNRB;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDNRB;CDK2 4636:[DB06616 DB07235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07235|N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE PRKACA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle CDK2;PRKACA;ABCB1 GO:0007596| blood coagulation LYN;PRKACA GO:0006468| protein phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;PRKACA;MAP3K2 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;PRKACA;CAMK2G;MAP3K2 GO:0034605| cellular response to heat PRKACA;LYN GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2 GO:0043393| regulation of protein binding PRKACA;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;PRKACA;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;PRKACA 4637:[DB06616 DB07963] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways GO:0006810| transport ABCB1;TTR 4638:[DB06616 DB11491] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 4639:[DB06616 DB02635] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways 4640:[DB06616 DB06751] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PDE4A GO:0007204| elevation of cytosolic calcium ion concentration CACNA1C;ABL1 GO:0055085| transmembrane transport ABCB1;CACNA1C GO:0007507| heart development CACNA1C;MAP2K1 GO:0006816| calcium ion transport CACNA1C;CAMK2G 4641:[DB06616 DB04926] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04926|Neramexane GRIN3A common genes common pathways GO:0006816| calcium ion transport CAMK2G;GRIN3A 4642:[DB06616 DB07132] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways GO:0018107| peptidyl-threonine phosphorylation MAP2K1;PDPK1;CAMK2G GO:0016477| cell migration PDPK1;SRC GO:0038095| LYN;PDPK1 GO:0046777| protein autophosphorylation CAMK2G;LYN;PDPK1;SRC;BCR;HCK;ABL1 GO:0030168| platelet activation SRC;LYN;PDPK1 GO:0032869| cellular response to insulin stimulus SRC;PDPK1 GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;PDPK1;CDK2;LYN;CAMK2G GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;PDPK1;CAMK2G;MAP3K2 GO:0031295| T cell costimulation LYN;PDPK1;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0007173| epidermal growth factor receptor signaling pathway PDPK1;SRC;ABL1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;ABL1 GO:0030036| actin cytoskeleton organization PDPK1;ABL1;BCR GO:0002223| stimulatory C-type lectin receptor signaling pathway PDPK1;LYN;SRC GO:0032148| activation of protein kinase B activity PDPK1;SRC GO:0035556| intracellular signal transduction PDPK1;LYN;CAMK2G;BCR;SRC GO:0018105| peptidyl-serine phosphorylation SRC;PDPK1;CDK2;CAMK2G GO:0043304| regulation of mast cell degranulation PDPK1;LYN 4643:[DB06616 DB01650] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport SLC22A8;ABCB1 4644:[DB06616 DB03928] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03928|Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol CTH common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;CTH 4645:[DB06616 DB07006] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07006|9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE WEE1 common genes common pathways GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2;WEE1 GO:0016310| phosphorylation CAMK2G;WEE1;CDK2;LYN;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0007049| cell cycle SRC;CDK2;WEE1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;WEE1;CDK2 GO:0051726| regulation of cell cycle WEE1;BCR;SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;WEE1;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0000082| G1/S transition of mitotic cell cycle CAMK2G;CDK2;WEE1 GO:0051301| cell division CDK2;WEE1 GO:0000278| mitotic cell cycle WEE1;ABL1 4646:[DB06616 DB04392] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04392|Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] NQO1;azoR common genes common pathways GO:0006979| response to oxidative stress ABL1;NQO1 GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1 GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0009636| response to toxin LYN;NQO1 GO:0006805| xenobiotic metabolic process CYP3A4;NQO1;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;HCK;NQO1 GO:0051602| response to electrical stimulus NQO1;SRC GO:0055114| oxidation-reduction process CYP2C8;NQO1;CYP3A4 4647:[DB06616 DB03611] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03611|L-2-amino-4-methoxy-cis-but-3-enoic acid MAT1A common genes common pathways 4648:[DB06616 DB00150] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;WARS GO:0010628| positive regulation of gene expression WARS;MAP2K1;SRC GO:0055085| transmembrane transport SLC16A10;SLC16A2;ABCB1 GO:0009636| response to toxin LYN;DDC GO:0002376| immune system process LYN;SRC;HCK;IDO1 GO:0006810| transport SLC16A2;ABCB1 GO:0006954| inflammatory response HCK;IDO1;LYN GO:0055114| oxidation-reduction process TDO2;CYP3A4;TPH2;TPH1;IDO1;CYP2C8 GO:0031667| response to nutrient levels TPH2;SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1;IDO1 GO:0001933| negative regulation of protein phosphorylation LYN;WARS GO:0032496| response to lipopolysaccharide IDO1;BCR 4649:[DB06616 DB02825] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0007399| nervous system development CAMK2G;ACHE GO:0006260| DNA replication ACHE;CDK2 GO:0008283| cell proliferation SRC;ACHE 4650:[DB06616 DB02854] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0038096| LYN;IGHG2;ABL1;SRC;HCK GO:0002250| adaptive immune response LYN;IGHG2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;HSD17B11 GO:0045087| innate immune response IGHG2;LYN;HCK;SRC;ABL1 GO:0006629| lipid metabolic process CYP3A4;SULT2A1;HSD17B11 GO:0050853| B cell receptor signaling pathway ABL1;IGHG2;LYN GO:0002376| immune system process IGHG2;LYN;SRC;HCK GO:0008202| steroid metabolic process CYP3A4;SULT2A1;CYP2C8 4651:[DB06616 DB06534] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06534|Thrombopoietin MPL common genes common pathways GO:0019221| cytokine-mediated signaling pathway HCK;MPL GO:0008283| cell proliferation MPL;SRC 4652:[DB06616 DB05166] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05166|APD668 GPR119 common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;GPR119;BCR;SRC GO:0030073| insulin secretion CAMK2G;GPR119 4653:[DB06616 DB11577] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug LYN;SRC;ADRA1A;ABCB1 GO:0006355| regulation of transcription, DNA-dependent AHR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2;AHR GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0007275| multicellular organismal development CDK2;CAMK2G;ADRA1D;ADRA1B GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;SRC;ADRA2A GO:0008284| positive regulation of cell proliferation CDK2;LYN;ADRA1D;ADRA2A;HCK GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;ADRA1A;ADRA1B GO:0006805| xenobiotic metabolic process AHR;CYP3A4;CYP2C8 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;ADRA1A;SRC GO:0006915| apoptotic process AHR;ABL1;ADRA1A GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;ADRA2B;MAP3K2 GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0009636| response to toxin AHR;LYN GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0007049| cell cycle CDK2;AHR;SRC GO:0045892| negative regulation of transcription, DNA-dependent AHR;SRC GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ABL1;ADRA1B GO:0030168| platelet activation SRC;ADRA2A;ADRA2B;LYN;ADRA2C GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0007165| signal transduction ADRA2C;LYN;ADRA2B;ADRA1D;ADRA1B;ADRA2A;BCR;ADRA1A;SRC;MAP2K1 GO:0009725| response to hormone stimulus LYN;ADRA1A 4654:[DB06616 DB01288] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0007165| signal transduction ADRB1;SRC;BCR;MAP2K1;ADRB3;LYN;ADRB2 GO:0045453| bone resorption SRC;ADRB2 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC 4655:[DB06616 DB04695] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04695|Farnesyl thiopyrophosphate ispU;GGPS1;MVK common genes common pathways GO:0008202| steroid metabolic process CYP3A4;MVK;CYP2C8 GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MVK;MAP3K2;CAMK2G;LYN;CDK2 GO:0050728| negative regulation of inflammatory response BCR;MVK GO:0006629| lipid metabolic process MVK;CYP3A4 4656:[DB06616 DB12077] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12077|Urelumab TNFRSF9 common genes common pathways GO:0006954| inflammatory response HCK;TNFRSF9;LYN GO:0007275| multicellular organismal development TNFRSF9;CAMK2G;CDK2 GO:0042127| regulation of cell proliferation TNFRSF9;SRC;ABL1 GO:0032496| response to lipopolysaccharide TNFRSF9;BCR GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;TNFRSF9 GO:0006915| apoptotic process TNFRSF9;ABL1 GO:0008285| negative regulation of cell proliferation TNFRSF9;LYN;MAP2K1 4657:[DB06616 DB06274] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;OPRK1;OPRD1;OPRM1;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;OPRM1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0008285| negative regulation of cell proliferation OPRM1;LYN;MAP2K1 GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0071222| cellular response to lipopolysaccharide ABL1;OPRK1;SRC;BCR GO:0010629| negative regulation of gene expression OPRD1;MAP2K1;MAP2K2 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 4658:[DB06616 DB06977] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06977|(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine PRKACA common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway PRKACA;LYN;SRC GO:0043393| regulation of protein binding PRKACA;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;PRKACA;CAMK2G GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;PRKACA GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;PRKACA;LYN;CDK2;CAMK2G GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;PRKACA;CAMK2G;MAP3K2 GO:0034605| cellular response to heat LYN;PRKACA GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA;CDK2 GO:0007596| blood coagulation PRKACA;LYN 4659:[DB06616 DB11431] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes ABCB1;CYP3A4 common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP3A5 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP3A7;CYP3A4 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A5;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP3A5;CYP2C8 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP3A43;CYP3A4;CYP3A7 GO:0099040| ABCB1 GO:0042493| response to drug SRC;ABCB1;ABCG2;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 4660:[DB06616 DB06292] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes CYP3A4;ABCB1 common pathways GO:0097267| CYP2C8;CYP1A2;CYP1A1;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A9;CYP1A2;CYP2A6;CYP3A4;CYP1A1;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0006810| transport ABCB1;SLC5A2 GO:0042908| xenobiotic transport ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT2B7;CYP2A6;CYP3A4;CYP2C9;CYP1A1;CYP1A2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0010033| response to organic substance CYP1A1;CDK2;CYP1A2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0055085| transmembrane transport SLC5A2;ABCB1 GO:0036378| CYP3A4 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0014070| response to organic cyclic compound CYP1A1;LYN;CYP1A2 GO:0009636| response to toxin LYN;CYP1A1 GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0008283| cell proliferation SRC;CYP1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP1A2;CYP2D6;UGT2B7 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;UGT2B4;CYP2C9;UGT1A9;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6;CYP1A1;CYP2C9;CYP1A2 GO:0009615| response to virus CYP1A1;SRC GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2D6 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide BCR;CYP1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP1A1;CYP3A4;CYP2D6 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP1A2;CYP2A6;CYP3A4;CYP1A1;CYP2C9 GO:0099040| ABCB1 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2A6;CYP2C9;CYP3A4;CYP1A2 4661:[DB06616 DB05042] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05042|SGS518 HTR6 common genes common pathways GO:0007165| signal transduction LYN;HTR6;MAP2K1;BCR;SRC 4662:[DB06616 DB05688] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0042493| response to drug SLC6A2;LYN;ABCB1;SRC;SLC6A4 GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0010033| response to organic substance SLC6A4;CDK2 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0055085| transmembrane transport SLC6A2;SLC6A4;ABCB1 GO:0009636| response to toxin LYN;SLC6A4 GO:0007420| brain development BCR;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 4663:[DB06616 DB04958] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04958|Epratuzumab CD22 common genes common pathways GO:0007155| cell adhesion ABL1;SRC;HCK;CD22 4664:[DB06616 DB04166] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;CYP2C8;IL4I1;CYP3A4 4665:[DB06616 DB00047] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;INSR GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;LYN;CDK2;IGF1R;MAP3K2;INSR GO:0016310| phosphorylation IGF1R;INSR;MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;INSR;IGF1R;HCK GO:0030335| positive regulation of cell migration INSR;IGF1R;LYN GO:0007165| signal transduction LYN;IGF1R;MAP2K1;BCR;SRC GO:0000187| activation of MAPK activity INSR;MAP3K2;MAP2K1;MAP2K2 GO:0046777| protein autophosphorylation CAMK2G;LYN;IGF1R;INSR;ABL1;BCR;SRC;HCK GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;INSR GO:0032148| activation of protein kinase B activity SRC;INSR GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;IGF1R;INSR GO:0043066| negative regulation of apoptotic process IGF1R;SRC;HCK GO:0035556| intracellular signal transduction SRC;BCR;INSR;CAMK2G;LYN GO:0023014| signal transduction via phosphorylation event LYN;INSR GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;INSR GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0038083| LYN;IGF1R;INSR;ABL1;SRC;HCK GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;SRC 4666:[DB06616 DB12890] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12890|Dihydrexidine DRD1 common genes common pathways GO:0042493| response to drug DRD1;ABCB1;SRC;LYN GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;DRD1 GO:1903351| ABL1;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;DRD1 GO:0030335| positive regulation of cell migration LYN;DRD1 4667:[DB06616 DB00130] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0043065| positive regulation of apoptotic process TGM2;ABL1;SRC GO:0002576| platelet degranulation F13A1;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ASNS GO:0009612| response to mechanical stimulus SRC;ASNS GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;GLS2;MAP3K2 GO:0007507| heart development CAD;MAP2K1 GO:0045931| positive regulation of mitotic cell cycle ASNS;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TGM2 GO:0016032| viral reproduction SLC1A5;HCK;SRC;LYN GO:0000082| G1/S transition of mitotic cell cycle PPAT;CDK2;CAMK2G GO:0042493| response to drug LYN;CTPS1;PFAS;SRC;ABCB1;PPAT GO:0031667| response to nutrient levels ASNS;SRC GO:0050900| leukocyte migration LYN;SLC7A8;SRC GO:0002376| immune system process HCK;SRC;LYN;CTPS1 GO:0007420| brain development SLC38A3;BCR;QARS GO:0017144| drug metabolic process CYP3A4;CAD;CYP2C8 GO:0032869| cellular response to insulin stimulus PPAT;SRC GO:0006810| transport ABCB1;SLC7A8 GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;HCK;CAD;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent QARS;SRC GO:0006464| protein modification process TGM5;ABL1;TGM3;TGM1 GO:0007596| blood coagulation F13A1;LYN GO:0030216| keratinocyte differentiation MAP2K1;TGM3;TGM1 GO:0008283| cell proliferation SRC;GLUL GO:0009636| response to toxin SLC7A8;LYN;ASNS GO:0043200| response to amino acid stimulus LYN;ASNS GO:0055085| transmembrane transport ABCB1;SLC38A3;SLC16A10 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAD;CAMK2G GO:0032868| response to insulin stimulus CAD;LYN GO:0045785| positive regulation of cell adhesion SRC;TGM2 GO:0042100| B cell proliferation CTPS1;ABL1 4668:[DB06616 DB08413] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08413|METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER IGKC;ALPP common genes common pathways GO:0045087| innate immune response LYN;IGKC;HCK;SRC;ABL1 GO:0050900| leukocyte migration LYN;IGKC;SRC GO:0038096| LYN;IGKC;HCK;SRC;ABL1 GO:0002250| adaptive immune response IGKC;LYN GO:0002376| immune system process HCK;SRC;LYN;IGKC GO:0038095| LYN;IGKC GO:0050853| B cell receptor signaling pathway LYN;IGKC;ABL1 4669:[DB06616 DB06579] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug GABRG3;SRC;ABCB1;LYN GO:0009791| post-embryonic development ABL1;GABRG2 GO:0006810| transport ABCB1;GABRA3;GABRA5;GABRG2;GABRA1;GABRA4;GABRA6 GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0007165| signal transduction LYN;GABRA6;GABRA5;MAP2K1;SRC;BCR GO:0007420| brain development GABRA5;BCR 4670:[DB06616 DB00459] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00459|Acitretin RXRA;RARA;RARB;RARG;RXRB;RXRG;RBP1;CYP26A1;ALB common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent SRC;RARA GO:0008285| negative regulation of cell proliferation LYN;RARB;RARA;MAP2K1;RARG GO:0010628| positive regulation of gene expression RARG;SRC;MAP2K1;RARA GO:0007165| signal transduction LYN;RARB;MAP2K1;RARA;SRC;BCR GO:0001843| neural tube closure RARA;ABL1;RARG GO:0006468| protein phosphorylation ABL1;MAP2K1;RARA;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0016032| viral reproduction HCK;SRC;RXRA;LYN GO:0060324| face development RARA;MAP2K1;RARG GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP26A1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1;RARA GO:0006355| regulation of transcription, DNA-dependent RXRA;RXRB;RARB;RARA;RARG;RXRG;ABL1 GO:0010629| negative regulation of gene expression RARA;MAP2K1;MAP2K2 GO:0042981| regulation of apoptotic process MAP3K2;RARA;MAP2K1;MAP2K2 GO:0007507| heart development MAP2K1;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;RARB;RARA;RXRA;CDK2 GO:0043066| negative regulation of apoptotic process ALB;RARG;RARA;HCK;RARB;SRC GO:0071300| cellular response to retinoic acid LYN;RARG;RARA GO:0006805| xenobiotic metabolic process CYP3A4;CYP26A1;CYP2C8 GO:0071222| cellular response to lipopolysaccharide RARA;BCR;SRC;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;RARG;RARA;HCK;RARB GO:0043065| positive regulation of apoptotic process SRC;RARB;ABL1;RARG GO:0002576| platelet degranulation LYN;ALB 4671:[DB06616 DB07427] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0042542| response to hydrogen peroxide SRC;HBA1;HBB GO:0007596| blood coagulation HBB;LYN 4672:[DB06616 DB03525] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03525|RU79073 SRC common genes SRC common pathways GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0042493| response to drug LYN;SRC;ABCB1 GO:0038083| LYN;HCK;SRC;ABL1 GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration SRC;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0038096| SRC;HCK;ABL1;LYN GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0038128| SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;LYN GO:0086098| SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN GO:0071398| cellular response to fatty acid SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0035635| entry of bacterium into host cell SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0007155| cell adhesion ABL1;SRC;HCK GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;HCK;ABL1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0043406| positive regulation of MAP kinase activity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0036120| SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2 GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0071456| cellular response to hypoxia SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC 4673:[DB06616 DB00117] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;SLC38A3;ABCB1 GO:0007420| brain development BCR;SLC38A3 4674:[DB06616 DB03976] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03976|Phosphorylisopropane PRSS1;PRSS2;CTRB1;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0045785| positive regulation of cell adhesion PRSS2;SRC GO:0042493| response to drug LYN;BCHE;ABCB1;SRC 4675:[DB06616 DB04472] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways GO:0010629| negative regulation of gene expression LGALS9;MAP2K1;MAP2K2 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;LGALS9 GO:0006954| inflammatory response LYN;LGALS9;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;LGALS9 GO:0032496| response to lipopolysaccharide BCR;LGALS9 GO:2000670| positive regulation of dendritic cell apoptosis LGALS9;LYN GO:0006935| chemotaxis MAP2K1;LGALS9 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;LGALS9 GO:0010628| positive regulation of gene expression LGALS9;SRC;MAP2K1 GO:0070555| response to interleukin-1 SRC;LGALS9 GO:1902715| ABL1;LGALS9 GO:0002376| immune system process LYN;LGALS9;SRC;HCK 4676:[DB06616 DB06749] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCB1 4677:[DB06616 DB00978] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0006810| transport ABCC2;ABCB1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0006855| drug transmembrane transport SLC22A5;ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2;SLC22A5 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;TOP2A GO:0043065| positive regulation of apoptotic process ABL1;SRC;TOP2A GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;ABCC2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;ABCC2;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;LYN;SRC;ABCB1;ABCC2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 4678:[DB06616 DB06714] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;TAAR1 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0009636| response to toxin LYN;SLC18A2 GO:0055085| transmembrane transport ABCB1;SLC18A2 4679:[DB06616 DB05034] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05034|Ularitide NPR1 common genes common pathways GO:0035556| intracellular signal transduction LYN;CAMK2G;NPR1;BCR;SRC GO:0043114| regulation of vascular permeability NPR1;BCR;SRC GO:0006468| protein phosphorylation MAP2K1;NPR1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G 4680:[DB06616 DB08210] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08210|2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE GCK common genes common pathways GO:0032869| cellular response to insulin stimulus GCK;SRC GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;GCK;MAP3K2;CAMK2G;LYN;CDK2 4681:[DB06616 DB01463] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01463|Fencamfamine SLC6A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0042493| response to drug SLC6A3;SRC;ABCB1;LYN 4682:[DB06616 DB04929] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04929|DG031 ALOX5AP common genes common pathways 4683:[DB06616 DB04602] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 4684:[DB06616 DB01561] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01561|Androstanedione HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HSD17B1;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;HSD17B1 4685:[DB06616 DB08597] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08597|6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine ACVR1;FKBP1A common genes common pathways GO:0023014| signal transduction via phosphorylation event ACVR1;LYN GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ACVR1;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0000082| G1/S transition of mitotic cell cycle ACVR1;CAMK2G;CDK2 GO:0019221| cytokine-mediated signaling pathway FKBP1A;HCK GO:0007498| mesoderm development HCK;ACVR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;ABL1 GO:0001933| negative regulation of protein phosphorylation FKBP1A;LYN GO:0007507| heart development MAP2K1;ACVR1 GO:0007179| transforming growth factor beta receptor signaling pathway ACVR1;SRC;FKBP1A GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;ACVR1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway ACVR1;SRC GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;ACVR1;MAP3K2 GO:0030335| positive regulation of cell migration ACVR1;LYN GO:0016310| phosphorylation MAP3K2;ACVR1;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 4686:[DB06616 DB07605] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07605|2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE F10 common genes common pathways GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration F10;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 4687:[DB06616 DB08733] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08733|(2R,3R)-N^1^-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N^4^-HYDROXY-2-(2-METHYLPROPYL)-3-{[(1,3-THIAZOL-2-YLCARBONYL)AMINO]METHYL}BUTANEDIAMIDE ADAM28 common genes common pathways 4688:[DB06616 DB03917] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways GO:0060065| uterus development SRC;RBP4 GO:0007507| heart development MAP2K1;RBP4 4689:[DB06616 DB05290] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05290|SPP 301 EDNRA common genes common pathways GO:0008283| cell proliferation SRC;EDNRA GO:0007165| signal transduction LYN;EDNRA;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;ABL1 GO:0007507| heart development MAP2K1;EDNRA 4690:[DB06616 DB09142] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09142|Sincalide SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3 4691:[DB06616 DB04299] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0034605| cellular response to heat LYN;TPR GO:0032869| cellular response to insulin stimulus GOT1;SRC GO:1900034| TPR;CAMK2G GO:0007049| cell cycle TPR;CDK2;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;CDK2 GO:0016032| viral reproduction HCK;SRC;TPR;LYN GO:0051301| cell division CDK2;TPR 4692:[DB06616 DB00529] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways GO:0050900| leukocyte migration SLC16A1;SRC;LYN GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC16A1;SLC22A6 4693:[DB06616 DB03807] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways GO:0050900| leukocyte migration LYN;PDE4B;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;PDE4B;ABL1 GO:0007165| signal transduction MAP2K1;SRC;BCR;PDE4B;LYN 4694:[DB06616 DB07194] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways GO:0046777| protein autophosphorylation LYN;SYK;CAMK2G;ABL1;HCK;BCR;SRC GO:0050853| B cell receptor signaling pathway ABL1;LYN;SYK GO:0038095| LYN;SYK GO:0008283| cell proliferation SRC;SYK GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;SYK GO:0007257| activation of JUN kinase activity SYK;MAP3K2 GO:0050715| positive regulation of cytokine secretion SRC;SYK GO:0002376| immune system process LYN;SYK;HCK;SRC GO:0070372| regulation of ERK1 and ERK2 cascade LYN;SYK GO:0051090| regulation of sequence-specific DNA binding transcription factor activity SYK;HCK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;SYK GO:0050764| regulation of phagocytosis HCK;SYK GO:0016310| phosphorylation MAP3K2;CAMK2G;SYK;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0030168| platelet activation SRC;LYN;SYK GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1;SYK GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2;SYK GO:0016032| viral reproduction LYN;SYK;HCK;SRC GO:0006954| inflammatory response LYN;SYK;HCK GO:0090330| regulation of platelet aggregation SYK;LYN GO:0002250| adaptive immune response SYK;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SYK;ABL1;SRC GO:0038096| ABL1;SRC;HCK;LYN;SYK GO:0038083| ABL1;HCK;SRC;LYN;SYK GO:0035556| intracellular signal transduction SRC;BCR;CAMK2G;SYK;LYN GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SYK;SRC GO:0045087| innate immune response SRC;HCK;ABL1;SYK;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;SYK GO:0002223| stimulatory C-type lectin receptor signaling pathway SYK;LYN;SRC 4695:[DB06616 DB09108] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09108|Simoctocog Alfa VWF common genes common pathways GO:0007155| cell adhesion VWF;ABL1;SRC;HCK GO:0002576| platelet degranulation LYN;VWF GO:0030168| platelet activation SRC;LYN;VWF GO:0007596| blood coagulation VWF;LYN 4696:[DB06616 DB07423] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;AR GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0051259| protein oligomerization CAMK2G;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;AR;HCK GO:0042327| positive regulation of phosphorylation AR;LYN 4697:[DB06616 DB02323] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02323|EM-1745 HSD17B1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HSD17B1 GO:0055114| oxidation-reduction process CYP2C8;HSD17B1;CYP3A4 4698:[DB06616 DB00713] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A2;SLC15A1 4699:[DB06616 DB06984] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06984|(1R,2R,3R,4S,5R)-4-(BENZYLAMINO)-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL MAN2A1 common genes common pathways 4700:[DB06616 DB02542] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways GO:0038095| UBB;LYN GO:0055085| transmembrane transport ABCB1;UBB GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;UBB GO:0007179| transforming growth factor beta receptor signaling pathway SRC;UBB GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;UBB;MAP3K2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;UBB GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;UBB GO:0016236| macroautophagy SRC;UBB GO:0038128| UBB;SRC GO:1902036| UBB;ABL1 GO:0000165| MAPKKK cascade UBB;CAMK2G;MAP2K1;MAP2K2 GO:0051436| negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle CDK2;UBB GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade UBB;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;UBB GO:0035635| entry of bacterium into host cell SRC;UBB GO:0043065| positive regulation of apoptotic process SRC;ABL1;UBB GO:1901796| CDK2;UBB GO:0043066| negative regulation of apoptotic process UBB;SRC;HCK GO:0045087| innate immune response ABL1;HCK;SRC;LYN;UBB GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;UBB 4701:[DB06616 DB01047] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0043066| negative regulation of apoptotic process SMO;HCK;SRC GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0008284| positive regulation of cell proliferation LYN;CDK2;SMO;HCK GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;SMO;CDK2 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0007275| multicellular organismal development SMO;CDK2;CAMK2G GO:0042737| drug catabolic process CYP3A4 GO:0051301| cell division NR3C1;CDK2 GO:0045893| positive regulation of transcription, DNA-dependent SMO;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;SMO GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;SMO;NR3C1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0007417| central nervous system development SMO;LYN;SRC GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;SRC;SMO GO:0045892| negative regulation of transcription, DNA-dependent SMO;SRC GO:0007049| cell cycle CDK2;NR3C1;SRC GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006915| apoptotic process ABL1;NR3C1 GO:0036378| CYP3A4 4702:[DB06616 DB04464] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0035635| entry of bacterium into host cell UBC;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;B2M GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;S100B GO:1901796| UBC;CDK2 GO:0043065| positive regulation of apoptotic process UBC;ABL1;SRC;S100B GO:0043066| negative regulation of apoptotic process SRC;HCK;UBC GO:0042981| regulation of apoptotic process RABGGTB;MAP3K2;RABGGTA;MAP2K1;MAP2K2 GO:0045087| innate immune response HLA-B;UBC;LYN;B2M;S100B;HCK;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter UBC;CDK2 GO:0008360| regulation of cell shape S100B;HCK GO:0051436| negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle UBC;CDK2 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;UBC;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade UBC;ABL1;S100B GO:0016032| viral reproduction LYN;HLA-B;SRC;HCK GO:0051602| response to electrical stimulus MT-CO1;SRC GO:0038128| UBC;SRC GO:1902036| UBC;ABL1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G;UBC GO:0016236| macroautophagy UBC;SRC GO:0042493| response to drug B2M;LYN;MT-ND1;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;MT-CO2;MT-CO1;MT-ND1;CYP2C8 GO:0060333| interferon-gamma-mediated signaling pathway HCK;B2M;CAMK2G;HLA-B GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;UBC GO:0002376| immune system process HCK;SRC;LYN;B2M;HLA-B GO:0006979| response to oxidative stress ABL1;MT-CO1 GO:0007417| central nervous system development S100B;SRC;COX7B;LYN GO:0071456| cellular response to hypoxia S100B;SRC GO:0006464| protein modification process RABGGTA;ABL1;RABGGTB GO:0090263| positive regulation of canonical Wnt receptor signaling pathway UBC;SRC GO:0045646| regulation of erythrocyte differentiation B2M;LYN GO:0008283| cell proliferation S100B;SRC GO:0038095| UBC;LYN GO:0007596| blood coagulation SERPINC1;LYN GO:0050690| regulation of defense response to virus by virus B2M;HCK GO:0014070| response to organic cyclic compound MT-ND1;LYN GO:0055085| transmembrane transport ABCB1;UBC GO:0000086| G2/M transition of mitotic cell cycle UBC;CDK2;ABCB1 GO:0007179| transforming growth factor beta receptor signaling pathway UBC;SRC GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;UBC 4703:[DB06616 DB02796] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02796|9-Deazainosine PNP common genes common pathways GO:0042493| response to drug PNP;LYN;SRC;ABCB1 4704:[DB06616 DB02162] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent HINT1;ABL1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;HINT1 GO:0006915| apoptotic process ABL1;HINT1 4705:[DB06616 DB08374] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways 4706:[DB06616 DB04260] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways GO:0042493| response to drug LYN;PNP;SRC;ABCB1 4707:[DB06616 DB08357] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion HCK;SRC;ABL1;ACHE GO:0006260| DNA replication ACHE;CDK2 GO:0008283| cell proliferation SRC;ACHE 4708:[DB06616 DB00010] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00010|Sermorelin GHRHR common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;GHRHR;LYN;CDK2 GO:0032868| response to insulin stimulus LYN;GHRHR GO:0032869| cellular response to insulin stimulus GHRHR;SRC GO:0007165| signal transduction LYN;GHRHR;MAP2K1;SRC;BCR 4709:[DB06616 DB08362] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08362|N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE CSNK2A1 common genes common pathways GO:0007049| cell cycle CDK2;CSNK2A1;SRC GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation CSNK2A1;CAMK2G;MAP2K1 GO:0007165| signal transduction CSNK2A1;LYN;MAP2K1;SRC;BCR GO:0006468| protein phosphorylation CSNK2A1;MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0016236| macroautophagy SRC;CSNK2A1 GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;CSNK2A1;HCK 4710:[DB06616 DB02049] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02049|2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide MMP13 common genes common pathways 4711:[DB06616 DB08900] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08900|Teduglutide GLP2R common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;GLP2R GO:0008284| positive regulation of cell proliferation CDK2;LYN;GLP2R;HCK 4712:[DB06616 DB13167] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13167|Alclofenac PTGS2 common genes common pathways GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0008284| positive regulation of cell proliferation HCK;PTGS2;LYN;CDK2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2C8 GO:0006954| inflammatory response PTGS2;LYN;HCK GO:0071498| cellular response to fluid shear stress SRC;PTGS2 4713:[DB06616 DB05941] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05941|Leronlimab CCR5 common genes common pathways GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;CCR5 GO:0006954| inflammatory response HCK;CCR5;LYN GO:0006816| calcium ion transport CCR5;CAMK2G GO:0016032| viral reproduction CCR5;LYN;SRC;HCK GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;CCR5 GO:0006935| chemotaxis CCR5;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCR5 GO:0007165| signal transduction CCR5;LYN;BCR;SRC;MAP2K1 4714:[DB06616 DB00182] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0055114| oxidation-reduction process MAOA;MAOB;CYP2A6;CYP3A4;CYP2D6;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2A6;CYP3A4 GO:0042493| response to drug ABCB1;SRC;DRD2;ADRA1A;SLC6A3;SLC6A4;SLC6A2;MAOB;LYN GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2B;ADRA2C GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;LYN;CDK2;ADRA1D GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2C8 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0035556| intracellular signal transduction DRD2;SRC;ADRA1A;BCR;ADRA1B;LYN;CAMK2G GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0048678| response to axon injury DRD2;LYN GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CDK2;CAMK2G GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;MAP2K1;LYN GO:0010033| response to organic substance SLC6A4;CDK2 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;ADRB2 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0055085| transmembrane transport SLC6A4;SLC6A3;ABCB1;SLC18A2;SLC22A5;SLC22A3;SLC6A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;DRD2;SRC;ADRA1A;MAP2K2;ABL1 GO:0006855| drug transmembrane transport ABCB1;SLC22A3;SLC22A5 GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;ADRA2B GO:0008283| cell proliferation SRC;ADRA1B;ADRA1D GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0009636| response to toxin LYN;SLC18A2;MAOB;SLC6A4;DRD2 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2D6;CYP2C8 GO:0007420| brain development BCR;SLC6A4 GO:0007165| signal transduction ADRB2;ADRA2B;LYN;ADRA2C;TAAR1;ADRA1D;ADRB3;ADRA2A;ADRA1B;CARTPT;MAP2K1;ADRB1;ADRA1A;SRC;DRD2;BCR GO:0030900| forebrain development DRD2;SRC GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0045453| bone resorption SRC;ADRB2 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1B;ABL1;ADRA1D GO:0006810| transport SLC6A2;ABCB1 GO:0000186| activation of MAPKK activity MAP3K2;CARTPT GO:0030168| platelet activation ADRA2C;ADRA2B;LYN;SRC;ADRA2A GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP2A6;CYP3A4 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0030335| positive regulation of cell migration LYN;ADRA2A 4715:[DB06616 DB03589] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03589|Alpha-Ketomalonic Acid ME2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;ME2 4716:[DB06616 DB00036] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways GO:0009725| response to hormone stimulus LYN;F7 GO:0030335| positive regulation of cell migration F10;LYN;F3;F7 GO:0010628| positive regulation of gene expression SRC;MAP2K1;HPN GO:0006464| protein modification process GGCX;ABL1 GO:0007596| blood coagulation F3;LYN;F10;GGCX;F7;TFPI GO:0014070| response to organic cyclic compound F7;LYN GO:0071222| cellular response to lipopolysaccharide TFPI;ABL1;SRC;BCR GO:0043066| negative regulation of apoptotic process SRC;HCK;HPN GO:0008360| regulation of cell shape HCK;HPN GO:0032496| response to lipopolysaccharide BCR;TFPI GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F3;SRC;F7 GO:0019221| cytokine-mediated signaling pathway HCK;F3 GO:0051897| positive regulation of protein kinase B signaling cascade F3;F10;F7;SRC GO:0031667| response to nutrient levels F7;SRC 4717:[DB06616 DB07567] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways GO:0060065| uterus development ESR1;SRC GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ESR1;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 4718:[DB06616 DB03660] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways GO:0007155| cell adhesion HCK;SRC;ABL1;DPP4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation SRC;LYN;DPP4 4719:[DB06616 DB01367] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01367|Rasagiline MAOB;BCL2;CYP1A2 common genes common pathways GO:0030097| hemopoiesis LYN;BCL2 GO:0003014| renal system process BCR;BCL2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0006979| response to oxidative stress BCL2;ABL1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0048538| thymus development BCL2;ABL1;MAP2K1 GO:0048536| spleen development ABL1;BCL2 GO:0045930| negative regulation of mitotic cell cycle BCL2;ABL1 GO:0071456| cellular response to hypoxia SRC;BCL2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0098609| BCL2;SRC GO:0014911| positive regulation of smooth muscle cell migration SRC;BCL2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008285| negative regulation of cell proliferation BCL2;LYN;MAP2K1 GO:0009791| post-embryonic development ABL1;CYP1A2;BCL2 GO:0030336| negative regulation of cell migration BCR;BCL2 GO:0050853| B cell receptor signaling pathway LYN;BCL2;ABL1 GO:0006915| apoptotic process ABL1;BCL2 GO:0055085| transmembrane transport ABCB1;BCL2 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;BCL2;MAP2K1 GO:0042100| B cell proliferation BCL2;ABL1 GO:0009636| response to toxin BCL2;MAOB;LYN GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0006470| protein dephosphorylation BCL2;CAMK2G GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis BCL2;ABL1 GO:0008283| cell proliferation BCL2;SRC GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;BCL2 GO:0006974| response to DNA damage stimulus ABL1;BCL2;LYN;CDK2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0042981| regulation of apoptotic process BCL2;MAP3K2;MAP2K2;MAP2K1 GO:0043066| negative regulation of apoptotic process HCK;SRC;BCL2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0008284| positive regulation of cell proliferation HCK;BCL2;CDK2;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G;BCL2 GO:0042542| response to hydrogen peroxide BCL2;SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1;BCL2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;MAOB;BCR GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0001782| B cell homeostasis BCL2;LYN GO:0051924| regulation of calcium ion transport BCL2;CAMK2G GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2 GO:2000811| negative regulation of anoikis SRC;BCL2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOB;CYP1A2 GO:0010506| regulation of autophagy BCL2;ABL1 GO:0051902| negative regulation of mitochondrial depolarization BCL2;SRC GO:0042493| response to drug MAOB;CYP1A2;BCL2;LYN;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 4720:[DB06616 DB06916] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NOS2 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;NOS2 GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC GO:0032496| response to lipopolysaccharide NOS2;BCR 4721:[DB06616 DB12271] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways 4722:[DB06616 DB02451] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02451|B-nonylglucoside RHO;AQP1;CLPS;PNLIP;MIP;KCNJ3 common genes common pathways GO:0006629| lipid metabolic process PNLIP;CYP3A4;CLPS GO:0071260| cellular response to mechanical stimulus MAP3K2;AQP1 GO:0071300| cellular response to retinoic acid LYN;AQP1 GO:0043066| negative regulation of apoptotic process HCK;SRC;AQP1 GO:0071732| cellular response to nitric oxide AQP1;CDK2 GO:0051602| response to electrical stimulus SRC;KCNJ3 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process AQP1;SRC GO:0042493| response to drug LYN;AQP1;SRC;ABCB1 GO:0007165| signal transduction MAP2K1;SRC;BCR;RHO;LYN GO:0006813| potassium ion transport CDK2;KCNJ3;AQP1 GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;RHO;MAP3K2 GO:0071456| cellular response to hypoxia SRC;AQP1 GO:0070301| cellular response to hydrogen peroxide ABL1;AQP1 GO:0045785| positive regulation of cell adhesion SRC;MIP GO:0055085| transmembrane transport ABCB1;AQP1;MIP 4723:[DB06616 DB03060] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03060|Sri-9662 DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4;CYP2C8 4724:[DB06616 DB01307] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR GO:0023014| signal transduction via phosphorylation event INSR;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;INSR GO:0038083| LYN;INSR;ABL1;SRC;HCK GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;INSR;MAP2K1;SRC;MAP2K2 GO:0032148| activation of protein kinase B activity SRC;INSR GO:0002576| platelet degranulation ALB;LYN GO:0008284| positive regulation of cell proliferation INSR;CDK2;LYN;HCK GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G;INSR GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0018108| peptidyl-tyrosine phosphorylation INSR;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;INSR;CAMK2G;LYN GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;INSR;MAP3K2 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;INSR GO:0032869| cellular response to insulin stimulus INSR;SRC GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;INSR;MAP3K2;CDK2;LYN;CAMK2G GO:0030335| positive regulation of cell migration INSR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;INSR;LYN 4725:[DB06616 DB02093] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02093|5-Phospho-D-Arabinohydroxamic Acid GPI common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;SRC 4726:[DB06616 DB01571] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0007165| signal transduction OPRK1;MAP2K1;BCR;SRC;LYN;OPRD1;OPRM1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;LYN;MAP2K1 GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;OPRK1 GO:0010629| negative regulation of gene expression OPRD1;MAP2K2;MAP2K1 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 4727:[DB06616 DB03367] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03367|PF-00356231 MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;CDK2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;MMP12 4728:[DB06616 DB01408] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0045453| bone resorption SRC;ADRB2 GO:0007165| signal transduction LYN;ADRB2;BCR;SRC;MAP2K1 GO:0042493| response to drug SRC;ABCB1;LYN;BCHE 4729:[DB06616 DB02689] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02689|S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine ARG1 common genes common pathways GO:0048678| response to axon injury ARG1;LYN GO:0032496| response to lipopolysaccharide BCR;ARG1 GO:0045087| innate immune response LYN;SRC;HCK;ABL1;ARG1 GO:0071222| cellular response to lipopolysaccharide ARG1;ABL1;BCR;SRC GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;SRC GO:0042493| response to drug LYN;ARG1;SRC;ABCB1 GO:0002250| adaptive immune response ARG1;LYN GO:0043434| response to peptide hormone stimulus ARG1;LYN GO:0002376| immune system process LYN;ARG1;SRC;HCK GO:0043200| response to amino acid stimulus ARG1;LYN GO:0070301| cellular response to hydrogen peroxide ABL1;ARG1 4730:[DB06616 DB00340] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation CDK2;LYN;CHRM1;HCK GO:0009615| response to virus CHRM2;SRC GO:0007399| nervous system development CHRM2;CAMK2G;CHRM1;CHRM3 GO:0008283| cell proliferation CHRM1;CHRM3;CHRM5;CHRM4;SRC GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0007165| signal transduction CHRM4;MAP2K1;SRC;BCR;CHRM2;LYN;CHRM1;CHRM3;CHRM5 4731:[DB06616 DB08737] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;MAP2K2;SRC;MAP2K1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0050727| regulation of inflammatory response HCK;ESR1;LYN GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0060065| uterus development ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction BCR;SRC;MAP2K1;ESR1;LYN 4732:[DB06616 DB04343] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways GO:0050900| leukocyte migration LYN;SLC16A3;SRC GO:0055085| transmembrane transport SLC16A3;ABCB1 4733:[DB06616 DB04478] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0042493| response to drug SORD;ABCB1;SRC;LYN GO:0031667| response to nutrient levels SRC;SORD GO:0055114| oxidation-reduction process SORD;CYP2C8;CYP3A4 GO:0009725| response to hormone stimulus LYN;SORD 4734:[DB06616 DB00324] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0051301| cell division CDK2;NR3C1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;NR3C1 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0006915| apoptotic process ABL1;NR3C1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007049| cell cycle SRC;NR3C1;CDK2 4735:[DB06616 DB01955] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01955|1,4-Butanediol MAN1B1;PLA2G2A;PLA2G2E common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;PLA2G2A GO:0006629| lipid metabolic process PLA2G2A;PLA2G2E;CYP3A4 GO:0006954| inflammatory response PLA2G2E;HCK;LYN 4736:[DB06616 DB07380] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 4737:[DB06616 DB02067] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways 4738:[DB06616 DB03341] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways GO:0014070| response to organic cyclic compound AANAT;LYN GO:0032868| response to insulin stimulus AANAT;LYN 4739:[DB06616 DB02477] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02477|[Cyclohexylethyl]-[[[[4-[2-Methyl-1-Imidazolyl-Butyl]Phenyl]Acetyl]-Seryl]-Lysinyl]-Amine NMT1 common genes common pathways 4740:[DB06616 DB05072] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05072|AV608 TACR1 common genes common pathways GO:0010634| positive regulation of epithelial cell migration SRC;TACR1 GO:0006954| inflammatory response HCK;LYN;TACR1 GO:0051602| response to electrical stimulus SRC;TACR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TACR1 GO:0009725| response to hormone stimulus LYN;TACR1 GO:0007165| signal transduction BCR;SRC;MAP2K1;TACR1;LYN GO:0014070| response to organic cyclic compound TACR1;LYN GO:0051496| positive regulation of stress fiber assembly TACR1;ABL1 4741:[DB06616 DB02648] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways GO:0006629| lipid metabolic process CRAT;CYP3A4;CROT 4742:[DB06616 DB02583] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 4743:[DB06616 DB01727] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01727|Isocitric Acid icd;icd;ACO2;IDH2;IDH1 common genes common pathways GO:0006979| response to oxidative stress IDH1;ABL1 GO:0014070| response to organic cyclic compound IDH1;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;IDH1;IDH2 4744:[DB06616 DB04629] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04629|Aplyronine A ACTA1 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;ACTA1 GO:0009612| response to mechanical stimulus SRC;ACTA1 4745:[DB06616 DB04230] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 4746:[DB06616 DB02078] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways GO:0006816| calcium ion transport CAMK2G;FYN GO:0016032| viral reproduction HCK;SRC;LYN;FYN GO:0010976| positive regulation of neuron projection development FYN;LYN GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;FYN;CAMK2G GO:0002250| adaptive immune response FYN;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;FYN GO:0038096| LYN;FYN;HCK;SRC;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway PPIF;SRC GO:0030036| actin cytoskeleton organization PFN2;ABL1;BCR GO:1901216| ABL1;FYN GO:0042493| response to drug SRC;ABCB1;FYN;LYN GO:0010629| negative regulation of gene expression FYN;MAP2K2;MAP2K1 GO:0038083| FYN;LYN;SRC;HCK;ABL1 GO:0050900| leukocyte migration LYN;FYN;SRC GO:0035556| intracellular signal transduction BCR;SRC;LYN;FYN;CAMK2G GO:0071560| cellular response to transforming growth factor beta stimulus SRC;FYN GO:0043066| negative regulation of apoptotic process HCK;SRC;PPIF GO:0048010| vascular endothelial growth factor receptor signaling pathway FYN;SRC GO:0008360| regulation of cell shape HCK;FYN GO:0045087| innate immune response FYN;LYN;ABL1;SRC;HCK GO:0042981| regulation of apoptotic process FYN;MAP3K2;PPIF;MAP2K2;MAP2K1 GO:0030838| positive regulation of actin filament polymerization PFN2;HCK GO:0042127| regulation of cell proliferation ABL1;SRC;FYN GO:0007275| multicellular organismal development CAMK2G;FYN;CDK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein FYN;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;FYN;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FYN;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;FYN;LYN GO:0050798| activated T cell proliferation FYN;ABL1 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;FYN;CAMK2G;LYN GO:0048013| ephrin receptor signaling pathway SRC;LYN;FYN GO:0070301| cellular response to hydrogen peroxide PPIF;ABL1 GO:0007411| axon guidance SRC;FYN GO:0071375| cellular response to peptide hormone stimulus SRC;FYN GO:0016477| cell migration SRC;FYN GO:0051496| positive regulation of stress fiber assembly ABL1;PFN2 GO:0050690| regulation of defense response to virus by virus FYN;HCK GO:0007596| blood coagulation FYN;LYN GO:0006915| apoptotic process PPIF;ABL1 GO:0006979| response to oxidative stress ABL1;PPIF GO:0002376| immune system process HCK;SRC;LYN;FYN GO:1900182| FYN;SRC GO:0030900| forebrain development SRC;FYN GO:0065009| regulation of molecular function FYN;CAMK2G GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;FYN GO:0007417| central nervous system development SRC;LYN;FYN GO:0036120| FYN;SRC GO:0031295| T cell costimulation LYN;FYN;SRC GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;FYN;CDK2;LYN GO:0030168| platelet activation FYN;LYN;SRC GO:0030154| cell differentiation CAMK2G;FYN;HCK GO:0006468| protein phosphorylation FYN;CAMK2G;LYN;CDK2;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK 4747:[DB06616 DB01942] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;FGF1;LYN GO:0007275| multicellular organismal development CAMK2G;FGF1;CDK2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;ABL1 GO:0006897| endocytosis CYTH2;ABL1 GO:0035556| intracellular signal transduction SRC;BCR;LYN;HMOX1;CAMK2G GO:0008284| positive regulation of cell proliferation CDK2;LYN;FGF1;HCK GO:0051726| regulation of cell cycle ABL1;SRC;BCR;CTBP1 GO:0042542| response to hydrogen peroxide SRC;HMOX1 GO:0043065| positive regulation of apoptotic process HMOX1;ABL1;SRC GO:0032148| activation of protein kinase B activity SRC;FGF1 GO:0007155| cell adhesion CASK;SRC;HCK;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CTBP1 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent CTBP1;ABL1 GO:0042738| exogenous drug catabolic process CYP2C8;NOS1;CYP3A4 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0055114| oxidation-reduction process CTBP1;GPHN;HMOX1;NOS1;CYP3A4;CYP2C8 GO:0001934| positive regulation of protein phosphorylation FGF1;LYN;ABL1 GO:0050900| leukocyte migration SRC;SLC16A3;LYN GO:0016032| viral reproduction CTBP1;LYN;SRC;HCK GO:0051897| positive regulation of protein kinase B signaling cascade SRC;FGF1 GO:0000165| MAPKKK cascade FGF1;CAMK2G;MAP2K2;MAP2K1 GO:0071498| cellular response to fluid shear stress SRC;CA2 GO:0030036| actin cytoskeleton organization ABL1;CYTH2;BCR GO:0034605| cellular response to heat HMOX1;FGF1;LYN GO:0030335| positive regulation of cell migration LYN;FGF1 GO:0016310| phosphorylation MAP3K2;CAMK2G;CASK;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0010595| positive regulation of endothelial cell migration FGF1;ABL1 GO:0071456| cellular response to hypoxia HMOX1;SRC GO:0030154| cell differentiation HCK;CAMK2G;FGF1;CTBP1 GO:0006468| protein phosphorylation MAP3K2;CTBP1;CDK2;LYN;CASK;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0006979| response to oxidative stress HMOX1;ABL1 GO:0065009| regulation of molecular function CAMK2G;CYTH2 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HMOX1;HCK GO:1902533| SRC;FGF1 GO:0007165| signal transduction FGF1;LYN;BCR;SRC;MAP2K1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis HMOX1;ABL1 GO:0008283| cell proliferation SRC;FGF1 GO:0000187| activation of MAPK activity FGF1;MAP3K2;MAP2K1;MAP2K2 GO:0006915| apoptotic process ABL1;HMOX1 GO:0055085| transmembrane transport ABCB1;SLC16A3 GO:0045892| negative regulation of transcription, DNA-dependent SRC;CTBP1 GO:0008285| negative regulation of cell proliferation CTBP1;HMOX1;LYN;MAP2K1 GO:0010033| response to organic substance CA2;CDK2 GO:0043406| positive regulation of MAP kinase activity SRC;FGF1 4748:[DB06616 DB08447] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;HCK;LYN GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 4749:[DB06616 DB08258] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP3A4;CYP2C8 GO:0010628| positive regulation of gene expression EPHX2;MAP2K1;SRC GO:0009636| response to toxin EPHX2;LYN GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2;CYP2C8 GO:0006954| inflammatory response EPHX2;LYN;HCK 4750:[DB06616 DB13508] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13508|Cloranolol CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 4751:[DB06616 DB01007] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes CYP3A4;CYP2C8 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0042493| response to drug LYN;CYP2E1;SRC;ABCB1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A4;CYP19A1;CYP2E1;CYP51A1 GO:0060065| uterus development CYP19A1;SRC GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2E1;CYP3A4 GO:0006082| organic acid metabolic process CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP51A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0097267| CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP51A1;CYP2E1;CYP3A4;CYP2C8;CYP2C19 4752:[DB06616 DB06711] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0035556| intracellular signal transduction LYN;CAMK2G;ADRA1A;SRC;BCR GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;ADRA2A GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0042493| response to drug LYN;ABCB1;ADRA1A;SRC GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0030168| platelet activation SRC;ADRA2A;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;ADRA1A;ADRA2A GO:0006915| apoptotic process ABL1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;ADRA1A;MAP2K2 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A 4753:[DB06616 DB00513] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;AOX1 GO:0006629| lipid metabolic process LPA;CYP3A4 GO:0002576| platelet degranulation LYN;PLG GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1;PLAT GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PLG GO:0006464| protein modification process PLAT;ABL1 GO:0007596| blood coagulation LYN;PLG;PLAT GO:0017144| drug metabolic process CYP2C8;AOX1;CYP3A4 4754:[DB06616 DB03964] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03964|4-Hydroxy-Aconitate Ion ACO2 common genes common pathways 4755:[DB06616 DB07666] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;LYN;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0043542| endothelial cell migration DPP4;ABL1 4756:[DB06616 DB04237] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways 4757:[DB06616 DB03115] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes MAP2K1 common pathways GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:1903800| MAP2K2;MAP2K1 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0048538| thymus development MAP2K1;ABL1 GO:0030878| thyroid gland development MAP2K1 GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN GO:0007050| cell cycle arrest MAP2K1;ABL1 GO:0030182| neuron differentiation ABL1;MAP2K1 GO:0030216| keratinocyte differentiation MAP2K1 GO:0060711| labyrinthine layer development MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0006928| cellular component movement MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0090170| regulation of Golgi inheritance MAP2K1;MAP2K2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1 GO:0001932| regulation of protein phosphorylation LYN;MAP2K1 GO:0048870| cell motility MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0048679| regulation of axon regeneration MAP2K1 GO:0060674| placenta blood vessel development MAP2K1 GO:0006935| chemotaxis MAP2K1 GO:0021697| cerebellar cortex formation MAP2K1 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;MAP2K1 GO:0007507| heart development MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1 GO:0050772| positive regulation of axonogenesis MAP2K1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2 GO:0007346| regulation of mitotic cell cycle MAP2K2;MAP2K1;MAP3K2 GO:0035897| proteolysis in other organism MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;SRC GO:0060440| trachea formation MAP2K1 GO:0060425| lung morphogenesis MAP2K1 GO:0060324| face development MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2 GO:0090398| cellular senescence MAP2K1 GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1 4758:[DB06616 DB03924] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03924|5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone CSNK2A1 common genes common pathways GO:0016236| macroautophagy SRC;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;CSNK2A1;CDK2;LYN GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CSNK2A1 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0007049| cell cycle CSNK2A1;CDK2;SRC GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;CSNK2A1;MAP3K2 GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;CSNK2A1;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0007165| signal transduction CSNK2A1;LYN;MAP2K1;BCR;SRC 4759:[DB06616 DB02489] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug SRC;ABCB1;CYP1A2;LYN 4760:[DB06616 DB13746] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes CYP2C8;CYP3A4 common pathways GO:0007165| signal transduction BCR;CACNA1I;SRC;MAP2K1;LYN GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4;CYP2C9 GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration CACNA1A;CACNA1C;ABL1 GO:0006810| transport CACNB1;CACNA1I;ABCB1;CACNB4;CACNB3 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2C9 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0055085| transmembrane transport CACNA1C;CACNA1F;CACNA1D;ABCB1;CACNA1I;CACNA1A;CACNA1H;CACNA1S;CACNA1G GO:0002933| CYP3A4;CYP2C8 GO:0007507| heart development CACNA1C;MAP2K1 GO:0006082| organic acid metabolic process CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2C19 GO:0006816| calcium ion transport CACNB1;CACNA1C;CACNA1F;CACNB4;CACNA1D;CACNA1I;CACNA1A;CACNB3;CACNB2;CAMK2G;CACNA1H;CACNA1S;CACNA1G GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C19;CYP2C8 4761:[DB06616 DB03802] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0007165| signal transduction ESR1;LYN;SRC;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0060065| uterus development ESR1;SRC GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 4762:[DB06616 DB04365] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM3;CHRM1;LYN;BCR;SRC;MAP2K1 GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0008283| cell proliferation SRC;CHRM3;CHRM1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRM1;HCK GO:0007399| nervous system development CAMK2G;CHRM1;CHRM3 4763:[DB06616 DB01593] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0051301| cell division BRCC3;CDK2 GO:0016032| viral reproduction SIVA1;SRC;TP73;CFH;HCK;IDE;LYN;HDAC1;APOA2;TP53;MDM2 GO:0002762| negative regulation of myeloid leukocyte differentiation LYN;NME1 GO:0006298| mismatch repair ABL1;TP73 GO:0050728| negative regulation of inflammatory response APOE;KRT1;APOA1;BCR GO:0006954| inflammatory response S100A9;BDKRB1;S100A8;LYN;KLKB1;C3;C5;HDAC4;KRT16;KNG1;HCK;SERPINA3;C4B GO:0070371| ERK1 and ERK2 cascade APOA1;MT3;MAP2K2;MAP2K1;AGT GO:0010976| positive regulation of neuron projection development AGT;NME1;APOE;LYN GO:0051897| positive regulation of protein kinase B signaling cascade APP;SRC;INS GO:0046628| positive regulation of insulin receptor signaling pathway INS;SRC GO:0002250| adaptive immune response FGA;JCHAIN;IGKV1-17;IGLV3-21;IGHM;LYN;IGHA1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;IL3;MAP2K2;INS GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1;FN1 GO:0051924| regulation of calcium ion transport AGT;CAMK2G GO:0019221| cytokine-mediated signaling pathway IL3;HCK GO:0031954| positive regulation of protein autophosphorylation SRC;INS GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;APP;TP53;VTN;ABL1;INS;AGT;SRC;IL3 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;MMP9 GO:1902036| TP73;ABL1 GO:0038096| ABL1;IGKV1-17;SRC;HCK;LYN;IGLV3-21 GO:0045893| positive regulation of transcription, DNA-dependent TP73;SRC;MAP2K2;AGT;MAP2K1;MT3;MAP3K2;TP53;ESR1;HDAC4;CDK2;HDAC1 GO:0031667| response to nutrient levels PON1;SOD1;PSPH;SRC GO:1901216| APOE;CLU;PARP1;APP;ABL1 GO:0006355| regulation of transcription, DNA-dependent HDAC8;INS;ABL1;ENO1;TP73;HDAC1;EEF1A1;HDAC4;ESR1;TP53;PARP1 GO:0010629| negative regulation of gene expression HDAC1;ESR1;APP;MDM2;NME1;HDAC8;AGT;MAP2K1;MAP2K2 GO:0007346| regulation of mitotic cell cycle MAP3K2;TP73;MAP2K2;MAP2K1 GO:0042493| response to drug APOA1;NME1;SRC;TP73;ABCB1;MGMT;HDAC4;LYN;HDAC1;SOD1;APOA2;TP53;MDM2 GO:0014003| oligodendrocyte development GSN;LYN GO:0034332| adherens junction organization JUP;SRC;DSP GO:0001934| positive regulation of protein phosphorylation APP;LYN;C3;MMP9;F2;ABL1;MT3 GO:0055114| oxidation-reduction process PDIA3;P4HB;GAPDHS;SOD1;CYP3A4;CP;CCS;PRDX1;CYP2C8;ADH1C GO:0006914| autophagy ABL1;TP53;S100A9;S100A8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;MT3;SRC GO:0050900| leukocyte migration JCHAIN;IGKV1-17;F2;SRC;LYN;IGHM;MMP9;FN1;IGHA1;IGLV3-21 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050885| neuromuscular process controlling balance APP;ABL1;BCR GO:0060065| uterus development ESR1;SRC GO:0030155| regulation of cell adhesion ABL1;GSN GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0009612| response to mechanical stimulus SRC;BDKRB1;PSPH GO:0043066| negative regulation of apoptotic process MT3;SRC;HCK;MGMT;HDAC1;SOD1;MMP9;TP53;MDM2 GO:0042327| positive regulation of phosphorylation LYN;APP GO:0071398| cellular response to fatty acid SRC;NME1 GO:0031571| mitotic cell cycle G1/S transition DNA damage checkpoint TP73;CDK2;TP53 GO:0030514| negative regulation of BMP signaling pathway DAND5;ABL1 GO:0006897| endocytosis APP;APLP1;NME1;ABL1 GO:0009615| response to virus ENO1;SRC;CLU GO:0042542| response to hydrogen peroxide SRC;HBA1;HBB;SOD1 GO:0006935| chemotaxis S100A8;S100A9;C5;MAP2K1;SERPIND1 GO:0008284| positive regulation of cell proliferation IL3;F2;HCK;AGT;INS;KRT6A;MDM2;FN1;HDAC4;HDAC1;LYN;CDK2 GO:0071732| cellular response to nitric oxide MT3;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response S100A8;S100A9;ESR1;LYN;HCK;PGLYRP2;AHSG GO:1901796| HDAC1;CDK2;TP53;MDM2;TP73 GO:0002576| platelet degranulation ITIH3;AHSG;A2M;APOA1;SERPINA1;SERPINA3;A1BG;KNG1;FGA;ITIH4;FN1;APLP2;SOD1;LYN;SERPINA4;ALDOA;CLU;ORM2;TF;APP GO:0043065| positive regulation of apoptotic process SRC;TP73;KNG1;ABL1;CLU;APP;TP53;SOD1;MMP9 GO:0006974| response to DNA damage stimulus TP73;MPG;ABL1;PARP1;TP53;BRCC3;LYN;CDK2;MGMT GO:0071260| cellular response to mechanical stimulus AGT;MAP3K2;HDAC4 GO:0006629| lipid metabolic process APOE;APOL1;CLU;PON1;C3;CYP3A4;APOBR;APOA1 GO:0006281| DNA repair MPG;ABL1;CDK2;MGMT;PARP1;BRCC3 GO:0051974| negative regulation of telomerase activity SRC;TP53 GO:0007399| nervous system development IL3;NME1;APP;CAMK2G;HDAC4;APLP1 GO:0042981| regulation of apoptotic process MAP2K1;AGT;MAP2K2;TP73;NME1;TP53;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;HDAC4;HDAC1;CDK2;PARP1;TP53;APP;MDM2;HDAC8;TP73;ENO1 GO:0007155| cell adhesion APP;VTN;APLP1;FN1;HCK;JUP;SRC;ABL1;IGFALS GO:0071801| regulation of podosome assembly HCK;SRC;GSN GO:0045087| innate immune response C4BPA;JCHAIN;CFB;PGLYRP2;ABL1;HCK;FGA;FCN3;SRC;C4B;C8G;CFH;C1QC;IGHM;CFI;C3;LYN;S100A7;IGHA1;KRT16;C5;C1S;C4BPB;APCS;S100A9;C8B;C8A;C1QB;APP;F12;C1R;APOL1;CLU;S100A8 GO:0007507| heart development MDM2;MAP2K1 GO:0032148| activation of protein kinase B activity SRC;INS;MT3 GO:0008360| regulation of cell shape FN1;ALDOA;HCK;F2 GO:0045597| positive regulation of cell differentiation INS;MAP2K1 GO:0001933| negative regulation of protein phosphorylation BDKRB1;LYN GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0051353| positive regulation of oxidoreductase activity ABL1;CCS GO:0045931| positive regulation of mitotic cell cycle APP;MDM2;ABL1 GO:0032496| response to lipopolysaccharide BCR;S100A7;HDAC1;BDKRB1;S100A8 GO:0030516| regulation of axon extension ABL1;APOE GO:0001932| regulation of protein phosphorylation LYN;FN1;APOA1;MAP2K1 GO:0042127| regulation of cell proliferation AGT;JUP;SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;BCR;IL3;SRC;ABL1;LYN GO:0048678| response to axon injury LYN;SOD1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL3;HDAC1;LYN GO:0007275| multicellular organismal development F2;HRNR;TP53;TPI1;CDK2;CAMK2G GO:0043542| endothelial cell migration S100A2;ABL1 GO:0034599| cellular response to oxidative stress PARP1;P4HB;HDAC1;SOD1;MGMT;PRDX1;CCS;MT3;ABL1 GO:0043393| regulation of protein binding APP;HDAC4;SRC GO:0007265| Ras protein signal transduction TP53;CDK2 GO:0034614| cellular response to reactive oxygen species TP53;MMP9;SRC GO:0010628| positive regulation of gene expression CLU;GSN;TP53;APP;MDM2;FN1;SRC;MAP2K1;INS;MT3 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050853| B cell receptor signaling pathway IGHM;LYN;IGHA1;ABL1 GO:0030336| negative regulation of cell migration BCR;KRT16 GO:1900272| APP;APOE;ABL1 GO:0006464| protein modification process ABL1;CPE GO:0045892| negative regulation of transcription, DNA-dependent MDM2;TP53;HDAC1;HDAC4;ENO1;SRC;MT3 GO:0050766| positive regulation of phagocytosis C3;BCR;AHSG GO:0014911| positive regulation of smooth muscle cell migration VTN;HDAC4;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;TP73;NME1;APP;TP53;HDAC1;LYN;HDAC4 GO:0010033| response to organic substance CDK2;SOD1 GO:0007049| cell cycle TP73;SRC;CDK2;TP53;BRCC3 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;JUP GO:0071375| cellular response to peptide hormone stimulus MDM2;SRC GO:0043407| negative regulation of MAP kinase activity LYN;APOE GO:0070301| cellular response to hydrogen peroxide MDM2;ABL1 GO:0048013| ephrin receptor signaling pathway LYN;MMP9;SRC GO:0014070| response to organic cyclic compound TP53;MGMT;LYN GO:0009636| response to toxin MDM2;MGMT;PON1;LYN GO:0050663| cytokine secretion LYN;AGT GO:0051496| positive regulation of stress fiber assembly ABL1;APOA1 GO:0043200| response to amino acid stimulus TP53;LYN GO:0016477| cell migration SRC;JUP;BDKRB1 GO:0038095| IGKV1-17;LYN;IGLV3-21 GO:0008283| cell proliferation KRT16;TP53;MT3;SRC;PRDX1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;FGA GO:0030216| keratinocyte differentiation MAP2K1;DSP;KRT10;S100A7;KRT16 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TP73 GO:0007596| blood coagulation SERPINA1;SERPIND1;FGA;KNG1;F2;HDAC1;LYN;KLKB1;HBB;F13B;F12;C4BPB GO:0031175| neuron projection development APP;LYN GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;MT3 GO:0007179| transforming growth factor beta receptor signaling pathway APOA1;SRC;PARP1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;PRDX1;MAP2K1 GO:0006915| apoptotic process PARP1;S100A9;APP;TP53;GSN;S100A8;CLU;APLP1;PDCD6;TP73;MT3;SIVA1;ABL1 GO:0000187| activation of MAPK activity TP73;MAP2K2;MAP2K1;C5;SOD1;MAP3K2;APP GO:0045184| establishment of protein localization MDM2;ABL1 GO:0055085| transmembrane transport APOA1;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;FGA;MAP2K2;SRC;MT3;ABL1;APP;S100A7 GO:0050715| positive regulation of cytokine secretion SRC;INS GO:0006979| response to oxidative stress SOD1;APP;TP53;APOE;MT3;KRT1;ABL1;PRDX1 GO:1900026| APOA1;ABL1;FGA GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;HCK;MT2A GO:0048538| thymus development ABL1;MAP2K1;SOD1 GO:0032463| negative regulation of protein homooligomerization CLU;SRC GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TP53;MDM2;CDK2 GO:0002376| immune system process IGKV1-17;PGLYRP2;CFB;C4BPA;CFH;C8G;C4B;FCN3;SRC;FGA;HCK;C1S;C5;IGHA1;LYN;C3;CFI;IGHM;C1QC;CLU;S100A8;IGLV3-21;C1R;C8A;C1QB;S100A9;C8B;C4BPB GO:0032489| regulation of Cdc42 protein signal transduction APOA1;ABL1;APOE GO:0007050| cell cycle arrest ABL1;TP73;MAP2K1;TP53 GO:0070542| response to fatty acid PON1;SRC GO:0065009| regulation of molecular function CAMK2G;AGT;IL3 GO:0070372| regulation of ERK1 and ERK2 cascade FN1;LYN GO:0070555| response to interleukin-1 SRC;HDAC4 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol BDKRB1;F2;ABL1 GO:0031648| protein destabilization SRC;GSN;MDM2 GO:1900182| F2;SRC;INS;PARP1 GO:0030900| forebrain development APP;SRC GO:0003014| renal system process BCR;AGT GO:0007420| brain development MT3;BCR GO:0051056| regulation of small GTPase mediated signal transduction A2M;BCR GO:0007165| signal transduction IGFALS;JUP;MAP2K1;FGA;BCR;SRC;LYN;C3;ESR1;PDIA3;BDKRB1 GO:0008202| steroid metabolic process CYP3A4;APOL1;APOE;APOBR;APOA1;CYP2C8 GO:0034605| cellular response to heat PDCD6;TP53;LYN GO:0098609| DSP;SRC;JUP GO:0072358| cardiovascular system development APOE;ABL1 GO:0043547| positive regulation of GTPase activity A2M;BCR GO:0030335| positive regulation of cell migration MMP9;LYN;INS GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;NME1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0010595| positive regulation of endothelial cell migration ABL1;PDCD6;AGT GO:0006810| transport ABCB1;TTR GO:0030168| platelet activation SRC;F2;FGA;LYN GO:0071456| cellular response to hypoxia SRC;MT3;P4HB;TP53;MDM2 GO:0007204| elevation of cytosolic calcium ion concentration APP;BDKRB1;ESR1;KNG1;AGT;ABL1 GO:0007229| integrin-mediated signaling pathway ABL1;APOA1;SRC;HCK GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;APP;MAP3K2;LYN;CDK2;CAMK2G GO:0030154| cell differentiation CAMK2G;TP53;KRT6A;NME1;HCK 4764:[DB06616 DB13893] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways GO:0006629| lipid metabolic process PLA2G10;CYP3A4 GO:0032869| cellular response to insulin stimulus SRC;ENPP1 GO:0007411| axon guidance SRC;PLA2G10 4765:[DB06616 DB08387] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0007165| signal transduction LYN;PDE10A;BCR;SRC;MAP2K1 4766:[DB06616 DB05932] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0016477| cell migration FLT1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;FLT4;VEGFA GO:0045785| positive regulation of cell adhesion SRC;VEGFA GO:0046777| protein autophosphorylation ABL1;HCK;SRC;BCR;FLT4;LYN;CAMK2G;FLT1 GO:0010628| positive regulation of gene expression VEGFA;MAP2K1;SRC GO:0043406| positive regulation of MAP kinase activity FLT1;VEGFA;SRC GO:0016310| phosphorylation CAMK2G;LYN;CDK2;FLT4;FLT1;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0010595| positive regulation of endothelial cell migration FLT4;VEGFA;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;FLT4;LYN;FLT1 GO:0030335| positive regulation of cell migration LYN;VEGFA;FLT1 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;FLT1;LYN GO:0071456| cellular response to hypoxia VEGFA;SRC GO:0030154| cell differentiation FLT1;VEGFA;CAMK2G;HCK GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;FLT1;FLT4;LYN;CDK2;CAMK2G GO:0010629| negative regulation of gene expression VEGFA;MAP2K2;MAP2K1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;ABL1 GO:0001934| positive regulation of protein phosphorylation VEGFA;LYN;FLT4;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;VEGFA GO:0031954| positive regulation of protein autophosphorylation SRC;VEGFA GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein VEGFA;LYN GO:0018108| peptidyl-tyrosine phosphorylation FLT1;FLT4;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0007275| multicellular organismal development VEGFA;FLT1;CDK2;CAMK2G GO:0007498| mesoderm development HCK;VEGFA GO:0006935| chemotaxis MAP2K1;FLT1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;FLT4;FLT1;VEGFA GO:0002576| platelet degranulation LYN;VEGFA GO:0051272| positive regulation of cellular component movement VEGFA;LYN GO:0043066| negative regulation of apoptotic process VEGFA;FLT4;SRC;HCK GO:0042327| positive regulation of phosphorylation VEGFA;LYN GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;FLT4;VEGFA;FLT1 GO:0007399| nervous system development VEGFA;CAMK2G GO:0008360| regulation of cell shape HCK;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;CDK2 4767:[DB06616 DB06786] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06786|Halcinonide SMO;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction LYN;SMO;MAP2K1;BCR;SRC GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0007417| central nervous system development SRC;SMO;LYN GO:0010628| positive regulation of gene expression SMO;SRC;MAP2K1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;SMO GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0043066| negative regulation of apoptotic process SMO;HCK;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;SMO;HCK GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;SMO GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0007275| multicellular organismal development CAMK2G;CDK2;SMO GO:0042737| drug catabolic process CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;SMO;MAP3K2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0010629| negative regulation of gene expression SMO;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 4768:[DB06616 DB07513] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07513|7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE MAOB common genes common pathways GO:0009636| response to toxin LYN;MAOB GO:0042493| response to drug ABCB1;SRC;LYN;MAOB GO:0055114| oxidation-reduction process MAOB;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide BCR;MAOB 4769:[DB06616 DB13141] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A5;CYP3A43;CYP3A4;CYP3A7 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP2C8;CYP3A5 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 4770:[DB06616 DB05096] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05096|LY2140023 GRM2;GRM3 common genes common pathways GO:0007165| signal transduction GRM2;BCR;SRC;MAP2K1;LYN;GRM3 4771:[DB06616 DB05343] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05343|Arundic acid S100B common genes common pathways GO:0008283| cell proliferation S100B;SRC GO:0071456| cellular response to hypoxia SRC;S100B GO:0007417| central nervous system development LYN;S100B;SRC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;S100B GO:0045087| innate immune response SRC;S100B;HCK;ABL1;LYN GO:0008360| regulation of cell shape S100B;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;S100B;HCK GO:0043065| positive regulation of apoptotic process ABL1;S100B;SRC 4772:[DB06616 DB00134] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process MTHFR;CYP3A4;MSRB2;MSRB1;MTRR;CYP2C8;MSRA GO:0006355| regulation of transcription, DNA-dependent MSRB2;ABL1 GO:0042493| response to drug ABCB1;SRC;MTHFR;LYN GO:0048678| response to axon injury MTR;LYN GO:0007399| nervous system development MTR;CAMK2G GO:0045087| innate immune response LYN;ABL1;HCK;MSRB1;SRC GO:0071732| cellular response to nitric oxide CDK2;MTR GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:0008283| cell proliferation SRC;GLUL GO:0043200| response to amino acid stimulus LYN;MTHFR GO:0006464| protein modification process MSRA;ABL1 GO:0032869| cellular response to insulin stimulus MARS;SRC GO:0036120| SRC;MARS GO:0070555| response to interleukin-1 SRC;MTHFR GO:0002376| immune system process LYN;HCK;MSRB1;SRC GO:0006979| response to oxidative stress ABL1;MSRA;MSRB1;MSRB2 4773:[DB06616 DB04973] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04973|LErafAON RAF1 common genes common pathways GO:0008283| cell proliferation SRC;RAF1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;RAF1 GO:0006915| apoptotic process RAF1;ABL1 GO:0008285| negative regulation of cell proliferation MAP2K1;RAF1;LYN GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;RAF1;MAP3K2 GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;RAF1;LYN;CDK2;CAMK2G GO:0030154| cell differentiation RAF1;CAMK2G;HCK GO:0000186| activation of MAPKK activity RAF1;MAP3K2 GO:0030168| platelet activation SRC;LYN;RAF1 GO:0048538| thymus development ABL1;MAP2K1;RAF1 GO:0030878| thyroid gland development MAP2K1;RAF1 GO:0007165| signal transduction BCR;SRC;MAP2K1;RAF1;LYN GO:0035023| regulation of Rho protein signal transduction BCR;RAF1 GO:0001934| positive regulation of protein phosphorylation RAF1;LYN;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;RAF1 GO:0048011| nerve growth factor receptor signaling pathway RAF1;SRC GO:0060324| face development MAP2K1;RAF1 GO:0000165| MAPKKK cascade RAF1;CAMK2G;MAP2K2;MAP2K1 GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;RAF1;SRC GO:0007275| multicellular organismal development CDK2;CAMK2G;RAF1 GO:0043066| negative regulation of apoptotic process HCK;SRC;RAF1 GO:2000145| regulation of cell motility RAF1;ABL1 GO:0035556| intracellular signal transduction BCR;SRC;RAF1;LYN;CAMK2G GO:0042981| regulation of apoptotic process RAF1;MAP3K2;MAP2K2;MAP2K1 GO:0007507| heart development MAP2K1;RAF1 4774:[DB06616 DB05895] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05895|HGS-TR2J TNFRSF10B common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process TNFRSF10B;SRC GO:0050900| leukocyte migration SRC;LYN;TNFRSF10B GO:0006954| inflammatory response TNFRSF10B;LYN;HCK GO:0007275| multicellular organismal development CAMK2G;CDK2;TNFRSF10B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNFRSF10B GO:0032496| response to lipopolysaccharide BCR;TNFRSF10B GO:0042127| regulation of cell proliferation TNFRSF10B;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus TNFRSF10B;MAP3K2 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;TNFRSF10B;MAP3K2 GO:0006915| apoptotic process ABL1;TNFRSF10B GO:0007165| signal transduction TNFRSF10B;LYN;MAP2K1;BCR;SRC 4775:[DB06616 DB02943] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways 4776:[DB06616 DB01327] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0010033| response to organic substance ABCC4;CDK2 GO:0009636| response to toxin PON1;SLC22A8;LYN GO:0014070| response to organic cyclic compound LYN;ABCC4 GO:0055085| transmembrane transport SLC22A6;SLC22A8;ABCB1;ABCC4;SLC22A11 GO:0045580| regulation of T cell differentiation IL15;ABL1 GO:0002376| immune system process SRC;HCK;IL2;LYN GO:0007165| signal transduction IL15;LYN;BCR;SRC;MAP2K1 GO:0070542| response to fatty acid SRC;PON1 GO:0065009| regulation of molecular function CAMK2G;IL2 GO:0007204| elevation of cytosolic calcium ion concentration IL2;ABL1 GO:0006954| inflammatory response HCK;LYN;IL15 GO:0050728| negative regulation of inflammatory response IL2;BCR GO:0002250| adaptive immune response IL2;LYN GO:0000165| MAPKKK cascade IL2;MAP2K1;MAP2K2;CAMK2G GO:0042493| response to drug LYN;ABCC4;SRC;ABCB1 GO:0031667| response to nutrient levels SRC;PON1;IL15 GO:0055114| oxidation-reduction process ABCC4;CYP2C8;CYP3A4 GO:0001934| positive regulation of protein phosphorylation ABL1;IL2;LYN GO:0008284| positive regulation of cell proliferation HCK;IL2;IL15;LYN;CDK2 GO:0002576| platelet degranulation LYN;ALB;ABCC4 GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB;IL2 GO:0007155| cell adhesion SRC;HCK;ABL1;IL2 GO:0006629| lipid metabolic process CYP3A4;PON1 GO:0001933| negative regulation of protein phosphorylation LYN;IL2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL15;IL2 4777:[DB06616 DB07280] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways GO:0016310| phosphorylation ADK;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MAP3K2 4778:[DB06616 DB03182] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 4779:[DB06616 DB02021] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC GO:0055114| oxidation-reduction process AKR1B10;CYP3A4;AKR1B1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;AKR1B10;CYP3A4 GO:0010033| response to organic substance CDK2;AKR1B1 4780:[DB06616 DB02164] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02164|N-Sulfo-Flavin Mononucleotide HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HAO1 4781:[DB06616 DB04616] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways GO:0006260| DNA replication CDK2;ACHE GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ACHE;SRC;HCK;ABL1 GO:0008283| cell proliferation ACHE;SRC 4782:[DB06616 DB03879] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03879|alpha-L-methyl-fucose MBL2 common genes common pathways GO:0050766| positive regulation of phagocytosis MBL2;BCR GO:0002376| immune system process MBL2;LYN;SRC;HCK GO:0006979| response to oxidative stress MBL2;ABL1 GO:0045087| innate immune response LYN;MBL2;SRC;HCK;ABL1 4783:[DB06616 DB13923] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13923|Emicizumab F9;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation F9;LYN;F10 4784:[DB06616 DB05771] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05771|LLL-3348 IL10 common genes common pathways GO:0032868| response to insulin stimulus IL10;LYN GO:0042100| B cell proliferation ABL1;IL10 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;IL10 GO:0008285| negative regulation of cell proliferation IL10;LYN;MAP2K1 GO:0010033| response to organic substance IL10;CDK2 GO:0030889| negative regulation of B cell proliferation LYN;IL10 GO:0045930| negative regulation of mitotic cell cycle IL10;ABL1 GO:0030097| hemopoiesis IL10;LYN GO:0050715| positive regulation of cytokine secretion SRC;IL10 GO:0042493| response to drug ABCB1;SRC;IL10;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;IL10 GO:0006954| inflammatory response HCK;IL10;LYN GO:0050728| negative regulation of inflammatory response IL10;BCR GO:0032496| response to lipopolysaccharide BCR;IL10 GO:0071222| cellular response to lipopolysaccharide IL10;SRC;BCR;ABL1 GO:0043066| negative regulation of apoptotic process IL10;HCK;SRC 4785:[DB06616 DB07470] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07470|(3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways GO:0008360| regulation of cell shape MYH14;HCK 4786:[DB06616 DB07333] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07333|N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;KDR;MAP2K1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0046777| protein autophosphorylation ABL1;SRC;BCR;HCK;KDR;CAMK2G;LYN GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR;ABL1 GO:0030154| cell differentiation KDR;HCK;CAMK2G GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;KDR;HCK;ABL1 GO:0030335| positive regulation of cell migration LYN;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;KDR;HCK GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;KDR GO:0010629| negative regulation of gene expression MAP2K2;KDR;MAP2K1 GO:0038083| ABL1;HCK;KDR;SRC;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;KDR GO:0016032| viral reproduction KDR;HCK;SRC;LYN GO:0007275| multicellular organismal development CAMK2G;CDK2;KDR GO:0018108| peptidyl-tyrosine phosphorylation ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0008360| regulation of cell shape KDR;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;KDR GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;KDR 4787:[DB06616 DB07840] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways GO:0007420| brain development BCR;FGFR1 GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;FGFR1;CAMK2G;LYN;CDK2;MAP3K2 GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;FGFR1;CAMK2G;CDK2;LYN;MAP3K2 GO:0046777| protein autophosphorylation FGFR1;CAMK2G;LYN;ABL1;BCR;SRC;HCK GO:0043406| positive regulation of MAP kinase activity FGFR1;SRC GO:0016477| cell migration FGFR1;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;FGFR1;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;FGFR1 GO:0042472| inner ear morphogenesis BCR;FGFR1 GO:0042127| regulation of cell proliferation FGFR1;SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation FGFR1;LYN;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0010976| positive regulation of neuron projection development LYN;FGFR1 GO:0000165| MAPKKK cascade CAMK2G;FGFR1;MAP2K1;MAP2K2 GO:0051897| positive regulation of protein kinase B signaling cascade FGFR1;SRC GO:0010629| negative regulation of gene expression FGFR1;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent FGFR1;ABL1 4788:[DB06616 DB05235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0030878| thyroid gland development MAP2K1;THRA GO:0006810| transport ABCB1;TTR GO:0045892| negative regulation of transcription, DNA-dependent SRC;THRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter CRYM;CDK2 GO:0030218| erythrocyte differentiation THRA;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;THRA GO:0055114| oxidation-reduction process CYP2C8;CRYM;CYP3A4 4789:[DB06616 DB01295] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0042493| response to drug LYN;SRC;ADRA1A;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;ADRA1A GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006915| apoptotic process ABL1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;ADRA1A;SRC;MAP2K2 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0045453| bone resorption ADRB2;SRC GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction MAP2K1;BCR;ADRB1;ADRA1A;SRC;ADRB2;LYN 4790:[DB06616 DB08164] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK 4791:[DB06616 DB01336] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways GO:0007165| signal transduction LYN;CHRM2;MAP2K1;CHRNA2;BCR;SRC GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM2;CAMK2G 4792:[DB06616 DB06655] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways GO:0043542| endothelial cell migration ABL1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK GO:0007155| cell adhesion HCK;SRC;ABL1;DPP4 GO:0031295| T cell costimulation SRC;DPP4;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;GLP1R GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;GLP1R 4793:[DB06616 DB05268] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05268|iCo-007 RAF1 common genes common pathways GO:2000145| regulation of cell motility ABL1;RAF1 GO:0035556| intracellular signal transduction LYN;CAMK2G;RAF1;SRC;BCR GO:0043066| negative regulation of apoptotic process HCK;SRC;RAF1 GO:0007507| heart development MAP2K1;RAF1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;RAF1;MAP3K2 GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;RAF1;SRC GO:0007275| multicellular organismal development CDK2;CAMK2G;RAF1 GO:0060324| face development MAP2K1;RAF1 GO:0000165| MAPKKK cascade CAMK2G;RAF1;MAP2K2;MAP2K1 GO:0035023| regulation of Rho protein signal transduction RAF1;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process RAF1;SRC GO:0048011| nerve growth factor receptor signaling pathway RAF1;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;RAF1;LYN GO:0048538| thymus development RAF1;MAP2K1;ABL1 GO:0030878| thyroid gland development RAF1;MAP2K1 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;RAF1 GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;RAF1;LYN;CDK2;CAMK2G GO:0006468| protein phosphorylation RAF1;MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0030154| cell differentiation HCK;CAMK2G;RAF1 GO:0000186| activation of MAPKK activity MAP3K2;RAF1 GO:0030168| platelet activation SRC;RAF1;LYN GO:0008285| negative regulation of cell proliferation LYN;RAF1;MAP2K1 GO:0008283| cell proliferation SRC;RAF1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;RAF1 GO:0006915| apoptotic process RAF1;ABL1 4794:[DB06616 DB04539] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP2C8;CYP19A1;CYP3A4 GO:0002576| platelet degranulation LYN;ALB GO:0060065| uterus development SRC;CYP19A1 GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK 4795:[DB06616 DB00162] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes common pathways GO:0007507| heart development RBP4;MAP2K1 GO:0006629| lipid metabolic process HPGDS;CYP3A4;APOD;RBP3 GO:0043065| positive regulation of apoptotic process ALDH1A3;ABL1;ALDH1A2;SRC GO:0002576| platelet degranulation ALB;LYN GO:0009615| response to virus CYP1A1;SRC GO:0008284| positive regulation of cell proliferation HCK;ALDH1A2;LYN;CDK2 GO:0071300| cellular response to retinoic acid ALDH1A2;LYN GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP26A1;CYP2C8 GO:0060065| uterus development SRC;RBP4 GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0048678| response to axon injury APOD;LYN GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;BCR GO:0042472| inner ear morphogenesis ALDH1A3;BCR GO:0060324| face development ALDH1A3;ALDH1A2;MAP2K1 GO:0050885| neuromuscular process controlling balance ABL1;BCR;ALDH1A3 GO:0055114| oxidation-reduction process RDH12;CYP26A1;RDH14;ALDH1A3;CYP1A1;CYP3A4;RETSAT;ALDH1A1;RDH5;RDH8;DHRS3;DHRS4;CYP2C8;RDH13;RDH11;ALDH1A2 GO:0042493| response to drug LYN;APOD;CYP1A1;SRC;ABCB1 GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A1 GO:0007420| brain development APOD;BCR GO:0007165| signal transduction LYN;MAP2K1;SRC;HPGDS;BCR GO:0030900| forebrain development ALDH1A2;SRC GO:0043547| positive regulation of GTPase activity ALDH1A1;BCR GO:0008202| steroid metabolic process CYP3A4;CYP1A1;DHRS4;CYP2C8 GO:0008285| negative regulation of cell proliferation MAP2K1;ALDH1A2;LYN GO:0010033| response to organic substance CYP1A1;CDK2 GO:0051895| negative regulation of focal adhesion assembly SRC;APOD GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0010628| positive regulation of gene expression ALDH1A2;MAP2K1;SRC GO:0008283| cell proliferation SRC;CYP1A1 GO:0030182| neuron differentiation ABL1;ALDH1A2;MAP2K1 GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0009636| response to toxin LYN;CYP1A1 4796:[DB06616 DB05372] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05372|CP-945598 CNR1 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;CNR1 GO:0010976| positive regulation of neuron projection development LYN;CNR1 GO:0032496| response to lipopolysaccharide BCR;CNR1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;CNR1 4797:[DB06616 DB02643] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02643|N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate IGF1;MAOB common genes common pathways GO:0032148| activation of protein kinase B activity SRC;IGF1 GO:0043066| negative regulation of apoptotic process SRC;HCK;IGF1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;IGF1 GO:0002576| platelet degranulation IGF1;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IGF1 GO:0007265| Ras protein signal transduction IGF1;CDK2 GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0006260| DNA replication IGF1;CDK2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;IGF1;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;IGF1 GO:0055114| oxidation-reduction process CYP2C8;MAOB;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;IGF1;MAP2K1;MAP2K2;SRC GO:0042493| response to drug MAOB;LYN;SRC;ABCB1 GO:0007165| signal transduction SRC;BCR;MAP2K1;IGF1;LYN GO:0030335| positive regulation of cell migration IGF1;LYN GO:0014911| positive regulation of smooth muscle cell migration SRC;IGF1 GO:0006928| cellular component movement MAP2K1;IGF1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;IGF1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;IGF1;MAP3K2 GO:0009636| response to toxin MAOB;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway IGF1;SRC GO:0008283| cell proliferation IGF1;SRC 4798:[DB06616 DB07908] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways GO:0030838| positive regulation of actin filament polymerization PFN1;HCK GO:0010634| positive regulation of epithelial cell migration SRC;PFN1 GO:0030036| actin cytoskeleton organization BCR;PFN1;ABL1 GO:0001843| neural tube closure PFN1;ABL1 4799:[DB06616 DB06586] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06586|Cetilistat PNLIP common genes common pathways GO:0006629| lipid metabolic process PNLIP;CYP3A4 4800:[DB06616 DB02684] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02684|5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 4801:[DB06616 DB00174] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0045931| positive regulation of mitotic cell cycle ASNS;ABL1 GO:0043066| negative regulation of apoptotic process SRC;HCK;ASNS GO:0009612| response to mechanical stimulus SRC;ASNS GO:0031667| response to nutrient levels ASNS;SRC GO:0016032| viral reproduction LYN;HCK;SLC1A5;SRC GO:0007420| brain development BCR;SLC38A3 GO:0009636| response to toxin LYN;ASNS GO:0043200| response to amino acid stimulus LYN;ASNS GO:0055085| transmembrane transport SLC38A3;ABCB1;SLC16A10 4802:[DB06616 DB04873] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04873|Piboserod HTR4 common genes common pathways GO:0007165| signal transduction HTR4;LYN;BCR;SRC;MAP2K1 4803:[DB06616 DB01154] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes CYP3A4 common pathways GO:0006813| potassium ion transport KCNJ8;CDK2;KCNJ11 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9;CYP2E1 GO:0006810| transport ABCB1;GABRA1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0055085| transmembrane transport KCNJ11;ABCB1 GO:0036378| CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP3A4 GO:0007507| heart development KCNJ8;MAP2K1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;KCNJ8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ABCB1;CYP2E1;KCNJ11;LYN GO:0055114| oxidation-reduction process CYP2E1;CYP2C9;CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 4804:[DB06616 DB07046] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes MAP2K1 common pathways GO:1903800| MAP2K2;MAP2K1 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MAP3K2 GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0048538| thymus development MAP2K1;ABL1 GO:0030878| thyroid gland development MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1 GO:0030182| neuron differentiation MAP2K1;ABL1 GO:0030216| keratinocyte differentiation MAP2K1 GO:0060711| labyrinthine layer development MAP2K1 GO:0090170| regulation of Golgi inheritance MAP2K1;MAP2K2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0006928| cellular component movement MAP2K1 GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN GO:0048679| regulation of axon regeneration MAP2K1 GO:0060674| placenta blood vessel development MAP2K1 GO:0001932| regulation of protein phosphorylation MAP2K1;LYN GO:0048870| cell motility MAP2K1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2 GO:0007507| heart development MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1 GO:0050772| positive regulation of axonogenesis MAP2K1 GO:0006935| chemotaxis MAP2K1 GO:0021697| cerebellar cortex formation MAP2K1 GO:0060425| lung morphogenesis MAP2K1 GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1 GO:0035897| proteolysis in other organism MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2 GO:0060440| trachea formation MAP2K1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1 GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1 GO:0060324| face development MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2 GO:0090398| cellular senescence MAP2K1 4805:[DB06616 DB02999] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02999|Quisqualate GRIA2;GRIK2 common genes common pathways GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0007165| signal transduction LYN;MAP2K1;SRC;GRIA2;BCR GO:0006810| transport ABCB1;GRIK2 4806:[DB06616 DB01356] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:1901216| GSK3B;ABL1 GO:0007275| multicellular organismal development CDK2;CAMK2G;GSK3B GO:0043066| negative regulation of apoptotic process GSK3B;SRC;HCK GO:0035556| intracellular signal transduction BCR;SRC;GSK3B;LYN;CAMK2G GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC;GSK3B GO:0007399| nervous system development CAMK2G;GSK3B GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;GSK3B;MAP3K2 GO:0031175| neuron projection development GSK3B;LYN GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1;GSK3B GO:0010628| positive regulation of gene expression GSK3B;SRC;MAP2K1 GO:0046777| protein autophosphorylation LYN;CAMK2G;GSK3B;ABL1;HCK;BCR;SRC GO:0043547| positive regulation of GTPase activity BCR;GSK3B GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;GSK3B;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0006810| transport ABCB1;GRIA3 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;GSK3B;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0030154| cell differentiation GSK3B;HCK;CAMK2G GO:1900034| GSK3B;CAMK2G GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;IMPA2;IMPA1 4807:[DB06616 DB02983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02983|Para-Mercury-Benzenesulfonic Acid CLC;ESR2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0007275| multicellular organismal development CLC;CAMK2G;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;ESR2 4808:[DB06616 DB01031] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01031|Ethinamate CA1;CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;SRC GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0010033| response to organic substance CA2;CDK2 4809:[DB06616 DB11937] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;GPR35 GO:0007204| elevation of cytosolic calcium ion concentration GPR35;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;AHR GO:0007049| cell cycle CDK2;AHR;SRC GO:0006915| apoptotic process AHR;ABL1 GO:0009636| response to toxin AHR;LYN GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;AHR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;AHR;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent AHR;ABL1 4810:[DB06616 DB06159] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06159|Rubitecan TOP1 common genes common pathways GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;TOP1;SRC GO:0016032| viral reproduction SRC;HCK;TOP1;LYN GO:0006260| DNA replication CDK2;TOP1 GO:0042493| response to drug LYN;TOP1;SRC;ABCB1 GO:0016310| phosphorylation LYN;CDK2;CAMK2G;TOP1;MAP3K2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC 4811:[DB06616 DB05501] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0007411| axon guidance CXCR4;SRC GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;CXCR4;MAP3K2 GO:0006915| apoptotic process CXCR4;ABL1 GO:0007165| signal transduction CXCR4;MAP2K1;SRC;BCR;LYN;CCR5 GO:0007204| elevation of cytosolic calcium ion concentration CCR5;ABL1;CXCR4 GO:0006954| inflammatory response CCR5;LYN;CXCR4;HCK GO:0006816| calcium ion transport CAMK2G;CCR5 GO:0016032| viral reproduction LYN;CCR5;CXCR4;HCK;SRC GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CCR5;CAMK2G GO:0006935| chemotaxis MAP2K1;CXCR4;CCR5 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;CCR5 GO:0009615| response to virus SRC;CXCR4 4812:[DB06616 DB07771] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07771|[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID KRAS;FNTA;FNTB common genes common pathways GO:0010628| positive regulation of gene expression SRC;KRAS;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;KRAS GO:0007411| axon guidance KRAS;SRC GO:0038095| KRAS;LYN GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;SRC GO:0007165| signal transduction SRC;KRAS;BCR;MAP2K1;LYN GO:0030036| actin cytoskeleton organization KRAS;BCR;ABL1 GO:0038128| KRAS;SRC GO:0019221| cytokine-mediated signaling pathway KRAS;HCK GO:0000165| MAPKKK cascade KRAS;MAP2K2;MAP2K1;CAMK2G GO:0007173| epidermal growth factor receptor signaling pathway ABL1;KRAS;SRC GO:0050900| leukocyte migration KRAS;SRC;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;KRAS;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;KRAS;HCK GO:0042127| regulation of cell proliferation FNTB;SRC;ABL1 GO:0051385| response to mineralocorticoid stimulus SRC;KRAS GO:0007265| Ras protein signal transduction KRAS;CDK2 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;KRAS;LYN 4813:[DB06616 DB03839] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03839|D-Tyrosine SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 4814:[DB06616 DB02400] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02400|5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0006979| response to oxidative stress NQO1;ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1;NQO1 GO:0014070| response to organic cyclic compound NQO1;LYN GO:0009636| response to toxin LYN;NQO1 GO:0006805| xenobiotic metabolic process CYP2C8;NQO1;CYP3A4 GO:0043066| negative regulation of apoptotic process NQO1;HCK;SRC GO:0051602| response to electrical stimulus NQO1;SRC GO:0055114| oxidation-reduction process CYP2C8;NQO1;CYP3A4 4815:[DB06616 DB06862] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;CASP3 GO:0006974| response to DNA damage stimulus LYN;CDK2;CASP3;ABL1 GO:0007507| heart development CASP3;MAP2K1 GO:0035556| intracellular signal transduction BCR;SRC;CASP3;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;SRC;ABL1 GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0048011| nerve growth factor receptor signaling pathway CASP3;SRC GO:0042493| response to drug CASP3;ABCB1;SRC;LYN GO:0001782| B cell homeostasis LYN;CASP3 GO:0030218| erythrocyte differentiation CASP3;LYN GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0006915| apoptotic process CASP3;ABL1 GO:0043200| response to amino acid stimulus CASP3;LYN GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0030216| keratinocyte differentiation MAP2K1;CASP3 GO:0030182| neuron differentiation ABL1;CASP3;MAP2K1 GO:0010033| response to organic substance CDK2;CASP3 4816:[DB06616 DB06492] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06492|Mirococept C3 common genes common pathways GO:0050766| positive regulation of phagocytosis C3;BCR GO:0007165| signal transduction LYN;C3;MAP2K1;SRC;BCR GO:0002376| immune system process SRC;HCK;C3;LYN GO:0006954| inflammatory response HCK;LYN;C3 GO:0001934| positive regulation of protein phosphorylation ABL1;C3;LYN GO:0045087| innate immune response C3;LYN;ABL1;SRC;HCK GO:0006629| lipid metabolic process CYP3A4;C3 4817:[DB06616 DB01426] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0002576| platelet degranulation LYN;ORM1 GO:0006954| inflammatory response HCK;ORM1;LYN GO:0055085| transmembrane transport ABCB1;SCN5A 4818:[DB06616 DB04551] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways GO:0055085| transmembrane transport SLCO2A1;ABCB1 GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;PKLR;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0032869| cellular response to insulin stimulus PKLR;SRC 4819:[DB06616 DB12520] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12520|Plozalizumab CCR2 common genes common pathways GO:0030097| hemopoiesis LYN;CCR2 GO:0007165| signal transduction LYN;SRC;CCR2;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCR2 GO:0016032| viral reproduction LYN;CCR2;SRC;HCK GO:0006954| inflammatory response LYN;CCR2;HCK GO:0019221| cytokine-mediated signaling pathway HCK;CCR2 GO:0006935| chemotaxis CCR2;MAP2K1 4820:[DB06616 DB07558] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways GO:0090263| positive regulation of canonical Wnt receptor signaling pathway PSMA7;SRC GO:0055085| transmembrane transport PSMA7;ABCB1 GO:0038095| LYN;PSMA7 GO:1902036| ABL1;PSMA7 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;PSMA7 GO:0016032| viral reproduction PSMA7;LYN;HCK;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PSMA7;SRC GO:0051436| negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle PSMA7;CDK2 4821:[DB06616 DB08830] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus SLC2A1;MAP3K2 GO:0032868| response to insulin stimulus SLC2A1;LYN GO:0055085| transmembrane transport ABCB1;SLC2A1 GO:0042908| xenobiotic transport ABCB1;SLC2A1 4822:[DB06616 DB07958] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2E GO:0006954| inflammatory response HCK;PLA2G2E;LYN 4823:[DB06616 DB00462] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007399| nervous system development CHRM2;CHRM1;CAMK2G;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0009615| response to virus SRC;CHRM2 GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0008283| cell proliferation SRC;CHRM1;CHRM3 GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRM1;LYN;CHRM2;CHRM3 4824:[DB06616 DB04850] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4 4825:[DB06616 DB05142] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05142|ND7001 PDE2A;PDE2A common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;PDE2A GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;CDK2 GO:0071560| cellular response to transforming growth factor beta stimulus PDE2A;SRC GO:0007165| signal transduction PDE2A;LYN;SRC;BCR;MAP2K1 4826:[DB06616 DB08949] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08949|Inositol nicotinate HCAR3;HCAR2;ATP5B;DGAT2;SLC5A8 common genes common pathways GO:0007165| signal transduction HCAR3;MAP2K1;HCAR2;SRC;BCR;LYN GO:0055085| transmembrane transport SLC5A8;ABCB1 GO:0006915| apoptotic process ABL1;SLC5A8;HCAR2 GO:0006629| lipid metabolic process DGAT2;ATP5B;CYP3A4 4827:[DB06616 DB06266] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;HK1;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0055085| transmembrane transport ABCB1;CFTR 4828:[DB06616 DB04724] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04724|(S)-2-((S)-3-ISOBUTYL-2,5-DIOXO-4-QUINOLIN-3-YLMETHYL-[1,4]DIAZEPAN-1YL)-N-METHYL-3-NAPHTALEN-2-YL-PROPIONAMIDE ITGAL common genes common pathways GO:0006928| cellular component movement ITGAL;MAP2K1 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;ITGAL GO:0098609| ITGAL;SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC;ITGAL GO:0006954| inflammatory response HCK;ITGAL;LYN GO:0006909| phagocytosis ITGAL;HCK;ABL1 GO:0050900| leukocyte migration SRC;LYN;ITGAL GO:0007155| cell adhesion ITGAL;ABL1;SRC;HCK 4829:[DB06616 DB04858] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0042493| response to drug LYN;CYP2E1;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1 4830:[DB06616 DB03348] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03348|Huperzine B ACHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0006260| DNA replication ACHE;CDK2 GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0007399| nervous system development CAMK2G;ACHE 4831:[DB06616 DB05930] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05930|SB-559448 MPL common genes common pathways GO:0008283| cell proliferation MPL;SRC GO:0019221| cytokine-mediated signaling pathway MPL;HCK 4832:[DB06616 DB01864] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways GO:0030154| cell differentiation CAMK2G;HCK;ARF6 GO:0030216| keratinocyte differentiation TGM3;MAP2K1 GO:0031175| neuron projection development RAB11A;LYN GO:0006928| cellular component movement MAP2K1;ARF6 GO:0006464| protein modification process ABL1;TGM3 GO:0007049| cell cycle CDK2;ARF6;RAB11A;SRC GO:0030838| positive regulation of actin filament polymerization ARF6;HCK GO:0007399| nervous system development ARF6;CAMK2G GO:0007155| cell adhesion HCK;SRC;ARF6;ABL1 GO:0010634| positive regulation of epithelial cell migration RAB11A;SRC GO:0051301| cell division CDK2;ARF6 4833:[DB06616 DB07528] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07528|3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one KDR common genes common pathways GO:0006468| protein phosphorylation MAP2K1;KDR;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0030154| cell differentiation HCK;KDR;CAMK2G GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation BCR;MAP2K2;SRC;KDR;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0030335| positive regulation of cell migration KDR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;KDR;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade KDR;MAP2K1;SRC;MAP2K2;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0046777| protein autophosphorylation HCK;KDR;SRC;BCR;ABL1;LYN;CAMK2G GO:0007275| multicellular organismal development KDR;CDK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation LYN;HCK;KDR;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0008360| regulation of cell shape KDR;HCK GO:0008284| positive regulation of cell proliferation KDR;HCK;CDK2;LYN GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process SRC;KDR;HCK GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;KDR;MAP2K1 GO:0038083| LYN;SRC;KDR;HCK;ABL1 GO:0070371| ERK1 and ERK2 cascade MAP2K2;KDR;MAP2K1 GO:0016032| viral reproduction LYN;KDR;HCK;SRC 4834:[DB06616 DB02071] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02071|WAY-151693 MMP13 common genes common pathways 4835:[DB06616 DB05457] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05457|OSI-7904L TYMS common genes common pathways GO:0009636| response to toxin TYMS;LYN GO:0014070| response to organic cyclic compound LYN;TYMS GO:0042493| response to drug TYMS;LYN;ABCB1;SRC 4836:[DB06616 DB02032] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 4837:[DB06616 DB04489] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 4838:[DB06616 DB11081] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11081|Aluminum chloride GLUD1 common genes common pathways GO:0055114| oxidation-reduction process GLUD1;CYP3A4;CYP2C8 4839:[DB06616 DB09295] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0034605| cellular response to heat PTGS2;LYN GO:0006810| transport CLCNKA;ABCB1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0055085| transmembrane transport CLCNKA;ABCB1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006954| inflammatory response HCK;PTGS1;PTGS2;LYN GO:0071498| cellular response to fluid shear stress PTGS2;SRC 4840:[DB06616 DB06011] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06011|AMG-222 DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;DPP4;LYN;CDK2 GO:0007155| cell adhesion SRC;HCK;ABL1;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation LYN;DPP4;SRC 4841:[DB06616 DB00811] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;IMPDH2;CYP3A4;IMPDH1 GO:0071456| cellular response to hypoxia SRC;SLC29A1 GO:0032869| cellular response to insulin stimulus SRC;ENPP1 GO:0016310| phosphorylation MAP3K2;NT5C2;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ADK;ABL1 GO:0017144| drug metabolic process NT5C2;CYP3A4;CYP2C8 4842:[DB06616 DB05395] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05395|Amibegron ADRB3 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;ADRB3;LYN 4843:[DB06616 DB08098] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08098|{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 4844:[DB06616 DB00577] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways GO:0055085| transmembrane transport SLC22A6;SLC22A8;SLC15A2;SLC15A1;ABCB1;SLC6A14;SLC10A2 GO:0009636| response to toxin SLC22A8;LYN;SLC6A14 GO:0006810| transport SLC15A2;SLC15A1;ABCB1;SLC6A14;SLC10A2 4845:[DB06616 DB00699] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00699|Nicergoline ADRA1A;CYP2D6 common genes common pathways GO:0042493| response to drug LYN;SRC;ADRA1A;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;ADRA1A;SRC GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;ADRA1A;MAP2K2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction MAP2K1;BCR;SRC;ADRA1A;LYN GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A 4846:[DB06616 DB01433] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01433|Methadyl acetate OPRM1 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;OPRM1 GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;OPRM1 4847:[DB06616 DB01171] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01171|Moclobemide MAOA;MAOA;MAOB;MAOB;MAOA;MAOB;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP2C8;CYP2C19 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0097267| CYP2C19;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2C9 GO:0009636| response to toxin MAOB;LYN GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;CYP2D6 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4;CYP2C9 GO:0042493| response to drug LYN;MAOB;SRC;ABCB1 GO:0055114| oxidation-reduction process MAOA;MAOB;CYP3A4;CYP2C9;CYP2D6;CYP2C8;CYP2C19 4848:[DB06616 DB05678] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05678|SLx-4090 MTTP common genes common pathways GO:0006629| lipid metabolic process CYP3A4;MTTP 4849:[DB06616 DB01397] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB;HCK;SRC GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0002576| platelet degranulation ALB;LYN GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;PTGS2;HCK GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC;PTGS1 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0006954| inflammatory response LYN;PTGS2;HCK;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0042493| response to drug LYN;PTGS2;ABCB1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 4850:[DB06616 DB06755] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06755|Beta carotene BCO1;VLDLR;RBP1;RBP2;RBP3;RBP4;RBP5 common genes common pathways GO:0007411| axon guidance VLDLR;SRC GO:0008202| steroid metabolic process CYP2C8;VLDLR;CYP3A4 GO:0007165| signal transduction BCR;SRC;MAP2K1;VLDLR;LYN GO:0055114| oxidation-reduction process CYP3A4;BCO1;CYP2C8 GO:0060065| uterus development RBP4;SRC GO:0006897| endocytosis VLDLR;ABL1 GO:0006629| lipid metabolic process RBP3;CYP3A4;VLDLR GO:0007399| nervous system development VLDLR;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter VLDLR;CDK2 GO:0007507| heart development MAP2K1;RBP4 4851:[DB06616 DB01017] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0048011| nerve growth factor receptor signaling pathway CASP3;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;SRC GO:0055114| oxidation-reduction process CYCS;CYP3A4;ALOX5;CYP2C8 GO:0001934| positive regulation of protein phosphorylation ABL1;IL1B;MMP9;LYN;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;VEGFA GO:0050900| leukocyte migration SRC;IL1B;LYN;MMP9 GO:0010506| regulation of autophagy CASP1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;IL1B;MAP2K1;MAP2K2;SRC GO:0010629| negative regulation of gene expression VEGFA;MAP2K1;MAP2K2 GO:0042493| response to drug CASP3;SRC;ABCB1;LYN GO:0001782| B cell homeostasis LYN;CASP3 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;IL1B;CAMK2G GO:0030218| erythrocyte differentiation CASP3;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MMP9;SRC GO:0009743| response to carbohydrate stimulus LYN;IL1B GO:0031954| positive regulation of protein autophosphorylation SRC;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;VEGFA GO:0019221| cytokine-mediated signaling pathway IL1B;HCK GO:0006954| inflammatory response LYN;IL1B;ALOX5;HCK GO:0007498| mesoderm development VEGFA;HCK GO:0007275| multicellular organismal development CDK2;CAMK2G;VEGFA GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein VEGFA;LYN GO:0034599| cellular response to oxidative stress ABL1;CYCS GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IL1B;CASP1 GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA GO:0032496| response to lipopolysaccharide IL1B;BCR;CASP3;CASP1 GO:0006974| response to DNA damage stimulus CDK2;LYN;CASP3;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;CASP1;IL1B GO:0051882| mitochondrial depolarization ABL1;CASP1 GO:0007507| heart development CASP3;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;CDK2 GO:0008360| regulation of cell shape HCK;VEGFA GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;CASP1 GO:0007399| nervous system development CAMK2G;VEGFA GO:0035556| intracellular signal transduction LYN;CAMK2G;CASP3;BCR;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway VEGFA;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;IL1B;LYN GO:0042327| positive regulation of phosphorylation LYN;VEGFA GO:0051272| positive regulation of cellular component movement VEGFA;LYN GO:0043066| negative regulation of apoptotic process CASP3;HCK;SRC;MMP9;VEGFA GO:0050727| regulation of inflammatory response LYN;CASP1;HCK GO:0043065| positive regulation of apoptotic process MMP9;CASP3;SRC;ABL1 GO:0002576| platelet degranulation VEGFA;LYN GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;CASP1 GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0008284| positive regulation of cell proliferation VEGFA;CDK2;LYN;HCK;IL1B GO:0006915| apoptotic process CASP1;CYCS;CASP3;ABL1;IL1B GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;IL1B;MAP3K2 GO:0045785| positive regulation of cell adhesion VEGFA;SRC GO:0055085| transmembrane transport ABCB1;SLC22A7;SLC22A11;SLC22A6;SLC22A8 GO:0070374| positive regulation of ERK1 and ERK2 cascade VEGFA;MAP2K1;MAP2K2;SRC;ABL1 GO:0006470| protein dephosphorylation CAMK2G;CYCS GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0009636| response to toxin SLC22A8;LYN GO:0014070| response to organic cyclic compound CASP3;LYN GO:0030182| neuron differentiation MAP2K1;CASP3;ABL1 GO:0030216| keratinocyte differentiation CASP3;MAP2K1 GO:0010033| response to organic substance CASP3;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;IL1B;LYN GO:0050766| positive regulation of phagocytosis IL1B;BCR GO:0043406| positive regulation of MAP kinase activity SRC;VEGFA GO:0048013| ephrin receptor signaling pathway LYN;MMP9;SRC GO:0043407| negative regulation of MAP kinase activity LYN;IL1B GO:0010628| positive regulation of gene expression SRC;MAP2K1;IL1B;VEGFA GO:0034614| cellular response to reactive oxygen species MMP9;SRC GO:0030154| cell differentiation VEGFA;CAMK2G;HCK GO:0030889| negative regulation of B cell proliferation LYN;CASP3 GO:0071456| cellular response to hypoxia VEGFA;SRC GO:0030335| positive regulation of cell migration IL1B;LYN;MMP9;VEGFA GO:0010595| positive regulation of endothelial cell migration VEGFA;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;IL1B GO:0007165| signal transduction LYN;CASP1;BCR;SRC;MAP2K1;IL1B GO:0050715| positive regulation of cytokine secretion SRC;CASP1 4852:[DB06616 DB03283] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03283|beta-L-fucose ACHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0006260| DNA replication CDK2;ACHE 4853:[DB06616 DB03712] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03712|RU85053 SRC common genes SRC common pathways GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0038083| LYN;HCK;SRC;ABL1 GO:0042493| response to drug ABCB1;SRC;LYN GO:0034332| adherens junction organization SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0050900| leukocyte migration LYN;SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction LYN;SRC;HCK GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0038128| SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| LYN;SRC;HCK;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0086098| SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0035635| entry of bacterium into host cell SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0033625| positive regulation of integrin activation SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response LYN;SRC;HCK;ABL1 GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0031295| T cell costimulation LYN;SRC GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0071456| cellular response to hypoxia SRC GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0048477| oogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process SRC;HCK;LYN GO:0045453| bone resorption SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN 4854:[DB06616 DB01728] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01728|3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-Glycerol RHO common genes common pathways GO:0007165| signal transduction RHO;LYN;MAP2K1;BCR;SRC GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;RHO;CDK2;LYN;CAMK2G 4855:[DB06616 DB02391] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;PNP 4856:[DB06616 DB02020] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02020|Alrestatin AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;HCK;AKR1B1 4857:[DB06616 DB02497] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02497|L-Alpha-Glycerophosphorylserine ANXA5 common genes common pathways GO:0007165| signal transduction ANXA5;LYN;SRC;BCR;MAP2K1 GO:0010033| response to organic substance CDK2;ANXA5 GO:0007596| blood coagulation ANXA5;LYN GO:0002576| platelet degranulation LYN;ANXA5 GO:0043066| negative regulation of apoptotic process ANXA5;HCK;SRC 4858:[DB06616 DB14498] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14498|Potassium acetate ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0042493| response to drug LYN;ATP1A1;SRC;ABCB1 GO:0006813| potassium ion transport CDK2;ATP1A1 4859:[DB06616 DB05478] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05478|Pradefovir Mesylate CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 4860:[DB06616 DB00456] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0055085| transmembrane transport ABCB1;SLC22A7;SLC22A11;SLC22A6;SLC15A1;SLC22A5;SLC15A2;SLC22A8 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0009636| response to toxin LYN;SLC22A8 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 4861:[DB06616 DB01178] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01178|Chlormezanone TSPO common genes common pathways GO:0008202| steroid metabolic process CYP3A4;TSPO;CYP2C8 GO:0007165| signal transduction LYN;TSPO;MAP2K1;BCR;SRC GO:0008283| cell proliferation SRC;TSPO GO:0006915| apoptotic process TSPO;ABL1 GO:0048678| response to axon injury LYN;TSPO GO:0060252| positive regulation of glial cell proliferation LYN;TSPO GO:0071222| cellular response to lipopolysaccharide TSPO;ABL1;SRC;BCR GO:0043065| positive regulation of apoptotic process SRC;ABL1;TSPO GO:0042493| response to drug LYN;TSPO;ABCB1;SRC 4862:[DB06616 DB03214] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways GO:0055114| oxidation-reduction process IL4I1;CYP3A4;CYP2C8 4863:[DB06616 DB06987] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;ABL1 GO:0045087| innate immune response LTF;ABL1;HCK;SRC;LYN GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 GO:0043066| negative regulation of apoptotic process LTF;HCK;SRC GO:0006355| regulation of transcription, DNA-dependent LTF;ABL1 GO:0001817| regulation of cytokine production LTF;LYN GO:0006954| inflammatory response LYN;HCK;PLA2G2E GO:0002376| immune system process SRC;HCK;LTF;LYN GO:0033690| positive regulation of osteoblast proliferation ABL1;LTF GO:0071902| positive regulation of protein serine/threonine kinase activity LTF;MAP2K1;SRC;MAP2K2 4864:[DB06616 DB11623] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11623|Candoxatrilat MME common genes common pathways 4865:[DB06616 DB02299] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02299|Arginineamide KCNA4 common genes common pathways GO:0055085| transmembrane transport KCNA4;ABCB1 GO:0006813| potassium ion transport CDK2;KCNA4 4866:[DB06616 DB11582] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0009636| response to toxin GABRB1;LYN GO:0007257| activation of JUN kinase activity TNFSF11;MAP3K2 GO:0009791| post-embryonic development GABRG2;ABL1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0030154| cell differentiation CAMK2G;TNFSF11;HCK GO:0006810| transport GABRA1;GABRA6;GABRA4;GABRB2;GABRD;GABRG2;GABRA5;GABRB1;GABRA3;GABRB3;ABCB1 GO:0045453| bone resorption SRC;TNFSF11 GO:0007165| signal transduction MAP2K1;SRC;BCR;GABRB3;GABRQ;GABRA5;GABRB1;GABRE;GABRP;LYN;GABRD;GABRA6 GO:0007420| brain development BCR;GABRA5 GO:1902533| TNFSF11;SRC GO:0042493| response to drug SRC;ABCB1;GABRG3;LYN GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAP2K2;MAP2K1 GO:0019221| cytokine-mediated signaling pathway TNFSF11;HCK GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ABL1 GO:0007275| multicellular organismal development TNFSF11;CAMK2G;CDK2 GO:0042327| positive regulation of phosphorylation TNFSF11;LYN 4867:[DB06616 DB03062] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03062|(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone NMT1;NMT1 common genes common pathways 4868:[DB06616 DB08799] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08799|Antazoline HRH1 common genes common pathways GO:0006954| inflammatory response LYN;HRH1;HCK GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0007165| signal transduction LYN;HRH1;BCR;SRC;MAP2K1 4869:[DB06616 DB03934] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways GO:0006470| protein dephosphorylation CYCS;CAMK2G GO:0006915| apoptotic process CYCS;ABL1 GO:0034599| cellular response to oxidative stress CYCS;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYCS 4870:[DB06616 DB06081] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06081|Caplacizumab VWF common genes common pathways GO:0002576| platelet degranulation LYN;VWF GO:0007155| cell adhesion ABL1;HCK;SRC;VWF GO:0030168| platelet activation LYN;VWF;SRC GO:0007596| blood coagulation VWF;LYN 4871:[DB06616 DB12637] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0006915| apoptotic process ABL1;NR3C1 GO:0007049| cell cycle CDK2;NR3C1;SRC GO:0007165| signal transduction NR3C1;LYN;MAP2K1;BCR;ADGRD1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0051301| cell division NR3C1;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 4872:[DB06616 DB07000] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways GO:0007165| signal transduction SRC;BCR;BRAF;MAP2K1;LYN GO:1900026| BRAF;ABL1 GO:0030878| thyroid gland development MAP2K1;BRAF GO:0048538| thymus development ABL1;MAP2K1;BRAF GO:0000186| activation of MAPKK activity MAP3K2;BRAF GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;MAP2K2;BRAF;BCR;HCK;MAP2K1;ABL1 GO:0030154| cell differentiation HCK;BRAF;CAMK2G GO:0043434| response to peptide hormone stimulus LYN;BRAF GO:0016310| phosphorylation MAP2K2;BRAF;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0046632| alpha-beta T cell differentiation BRAF;ABL1 GO:0010628| positive regulation of gene expression SRC;BRAF;MAP2K1 GO:0045580| regulation of T cell differentiation BRAF;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;BRAF;MAP2K1;ABL1 GO:0051496| positive regulation of stress fiber assembly BRAF;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis BRAF;ABL1 GO:0050772| positive regulation of axonogenesis MAP2K1;BRAF GO:0035556| intracellular signal transduction BRAF;BCR;SRC;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process HCK;BRAF;SRC GO:0048679| regulation of axon regeneration BRAF;MAP2K1 GO:0042127| regulation of cell proliferation BRAF;SRC;ABL1 GO:0000165| MAPKKK cascade BRAF;MAP2K2;MAP2K1;CAMK2G GO:0060324| face development MAP2K1;BRAF 4873:[DB06616 DB07070] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways GO:0030154| cell differentiation HCK;CAMK2G;PPARD GO:0071456| cellular response to hypoxia PPARD;SRC GO:0008283| cell proliferation SRC;PPARD GO:0006915| apoptotic process ABL1;PPARD GO:0010628| positive regulation of gene expression MAP2K1;SRC;PPARD GO:0010033| response to organic substance CDK2;PPARD GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARD GO:0042127| regulation of cell proliferation PPARD;ABL1;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;PPARD GO:0008284| positive regulation of cell proliferation PPARD;LYN;CDK2;HCK GO:0043066| negative regulation of apoptotic process PPARD;HCK;SRC GO:0007507| heart development MAP2K1;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARD GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARD;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;PPARD;SRC;MAP2K2;MAP2K1 GO:0050728| negative regulation of inflammatory response PPARD;BCR 4874:[DB06616 DB05447] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05447|AVI-4557 HNF4A common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;HNF4A GO:0006629| lipid metabolic process CYP3A4;HNF4A GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;MAP2K2;HNF4A;SRC GO:0006355| regulation of transcription, DNA-dependent HNF4A;ABL1 GO:0008285| negative regulation of cell proliferation LYN;HNF4A;MAP2K1 GO:0007596| blood coagulation LYN;HNF4A 4875:[DB06616 DB07485] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07485|4,4'-cyclohexane-1,1-diyldiphenol ESRRG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;ESRRG GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;ESRRG;MAP2K1;SRC;MAP2K2 4876:[DB06616 DB00982] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00982|Isotretinoin RARA common genes common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1;RARA GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;RARA GO:0045892| negative regulation of transcription, DNA-dependent SRC;RARA GO:0007165| signal transduction LYN;MAP2K1;RARA;BCR;SRC GO:0001843| neural tube closure RARA;ABL1 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;RARA;ABL1 GO:0060324| face development MAP2K1;RARA GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;RARA;MAP2K1;MAP2K2;SRC GO:0010629| negative regulation of gene expression MAP2K2;RARA;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;RARA GO:0071300| cellular response to retinoic acid LYN;RARA GO:0043066| negative regulation of apoptotic process SRC;RARA;HCK GO:0071222| cellular response to lipopolysaccharide ABL1;RARA;SRC;BCR GO:0008284| positive regulation of cell proliferation RARA;HCK;CDK2;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARA GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;RARA;MAP2K2 4877:[DB06616 DB05107] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;G6PD GO:0014070| response to organic cyclic compound LYN;G6PD GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;G6PD GO:0034599| cellular response to oxidative stress G6PD;ABL1 GO:0006629| lipid metabolic process CYP3A4;G6PD 4878:[DB06616 DB01990] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01990|Cholesterol sulfate RORA common genes common pathways GO:0071456| cellular response to hypoxia SRC;RORA GO:0050728| negative regulation of inflammatory response BCR;RORA GO:0006355| regulation of transcription, DNA-dependent ABL1;RORA GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;RORA;MAP3K2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;RORA GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade RORA;ABL1 4879:[DB06616 DB03682] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 4880:[DB06616 DB02868] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways GO:0038095| CALM1;LYN GO:0055085| transmembrane transport ABCB1;CALM1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;CALM1 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CALM1;CAMK2G GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0002576| platelet degranulation LYN;CALM1 4881:[DB06616 DB01328] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01328|Cefonicid mrcA;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation ALB;LYN 4882:[DB06616 DB00202] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CHRNA10 GO:0007165| signal transduction MAP2K1;CHRNA10;BCR;SRC;CHRNA7;CHRM3;LYN;CHRM2;CHRM1 GO:0008283| cell proliferation SRC;CHRM3;CHRM1 GO:0000187| activation of MAPK activity MAP3K2;CHRNA7;MAP2K2;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;CHRNA7;MAP2K2;SRC;MAP2K1 GO:0006464| protein modification process CHRM3;CHRM1;ABL1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0042472| inner ear morphogenesis BCR;CHRNA10 GO:0042127| regulation of cell proliferation ABL1;CHRNA10;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRM1;CHRNA7;HCK GO:0009615| response to virus CHRM2;SRC GO:0007399| nervous system development CHRM1;CAMK2G;CHRM2;CHRM3 GO:0042493| response to drug ABCB1;SRC;BCHE;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;LYN GO:0006816| calcium ion transport CAMK2G;CHRNA10;CHRNA7 4883:[DB06616 DB13178] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13178|Inositol SLC5A3 common genes common pathways GO:0006810| transport SLC5A3;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC5A3 4884:[DB06616 DB12670] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12670|Rolofylline ADORA1 common genes common pathways GO:0043066| negative regulation of apoptotic process ADORA1;HCK;SRC GO:0007399| nervous system development CAMK2G;ADORA1 GO:0006954| inflammatory response ADORA1;LYN;HCK GO:0050728| negative regulation of inflammatory response ADORA1;BCR GO:0006909| phagocytosis HCK;ABL1;ADORA1 GO:0007165| signal transduction BCR;SRC;MAP2K1;ADORA1;LYN GO:0000186| activation of MAPKK activity MAP3K2;ADORA1 GO:0008285| negative regulation of cell proliferation MAP2K1;ADORA1;LYN 4885:[DB06616 DB03591] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03591|RU82209 SRC common genes SRC common pathways GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0045087| innate immune response LYN;ABL1;SRC;HCK GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0035635| entry of bacterium into host cell SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0086098| SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0045056| transcytosis SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| HCK;SRC;ABL1;LYN GO:0016032| viral reproduction SRC;HCK;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0034332| adherens junction organization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0050900| leukocyte migration LYN;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0038083| LYN;ABL1;HCK;SRC GO:0042493| response to drug SRC;ABCB1;LYN GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0071456| cellular response to hypoxia SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0048477| oogenesis SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0060491| regulation of cell projection assembly SRC GO:0016310| phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0031295| T cell costimulation SRC;LYN GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0007411| axon guidance SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;BCR;SRC;HCK GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0045785| positive regulation of cell adhesion SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC 4886:[DB06616 DB05243] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05243|XL019 JAK2 common genes common pathways GO:0006915| apoptotic process JAK2;ABL1 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;JAK2 GO:0007596| blood coagulation LYN;JAK2 GO:0016477| cell migration SRC;JAK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;JAK2 GO:0046777| protein autophosphorylation HCK;SRC;BCR;ABL1;JAK2;LYN;CAMK2G GO:0006928| cellular component movement MAP2K1;JAK2 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;JAK2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0030154| cell differentiation CAMK2G;JAK2;HCK GO:0007204| elevation of cytosolic calcium ion concentration ABL1;JAK2 GO:0000186| activation of MAPKK activity MAP3K2;JAK2 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2;JAK2 GO:0030335| positive regulation of cell migration LYN;JAK2 GO:0007165| signal transduction LYN;JAK2;MAP2K1;SRC;BCR GO:0002376| immune system process SRC;HCK;JAK2;LYN GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;JAK2;HCK GO:0022408| negative regulation of cell-cell adhesion JAK2;ABL1 GO:0006979| response to oxidative stress JAK2;ABL1 GO:0038083| SRC;HCK;ABL1;JAK2;LYN GO:0019221| cytokine-mediated signaling pathway HCK;JAK2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;JAK2;ABL1;SRC GO:0000165| MAPKKK cascade JAK2;CAMK2G;MAP2K2;MAP2K1 GO:0030218| erythrocyte differentiation JAK2;LYN GO:0002250| adaptive immune response JAK2;LYN GO:0007498| mesoderm development HCK;JAK2 GO:0018108| peptidyl-tyrosine phosphorylation JAK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein JAK2;LYN GO:0042127| regulation of cell proliferation JAK2;ABL1;SRC GO:0032496| response to lipopolysaccharide BCR;JAK2 GO:0048008| platelet-derived growth factor receptor signaling pathway JAK2;BCR;SRC;ABL1 GO:0045087| innate immune response HCK;SRC;ABL1;JAK2;LYN GO:0045597| positive regulation of cell differentiation JAK2;MAP2K1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;JAK2 GO:0050727| regulation of inflammatory response HCK;LYN;JAK2 GO:0043065| positive regulation of apoptotic process JAK2;SRC;ABL1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;JAK2 GO:0035556| intracellular signal transduction SRC;BCR;JAK2;CAMK2G;LYN 4887:[DB06616 DB11692] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11692|Pavinetant TACR3 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;TACR3;LYN 4888:[DB06616 DB07157] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways 4889:[DB06616 DB06282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06282|Levocetirizine HRH1 common genes common pathways GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0006954| inflammatory response HCK;HRH1;LYN GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;HRH1 4890:[DB06616 DB01404] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01404|Ginseng IL6;PTGS2;AHR common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;IL6;HCK;SRC GO:0006805| xenobiotic metabolic process CYP3A4;AHR;CYP2C8 GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;IL6;HCK GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;IL6 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;IL6;SRC GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL6;LYN GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0019221| cytokine-mediated signaling pathway HCK;IL6 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;IL6;SRC;ABL1 GO:0006954| inflammatory response HCK;IL6;LYN;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;IL6;MAP2K1;AHR;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;AHR GO:0042493| response to drug PTGS2;LYN;SRC;ABCB1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0030168| platelet activation IL6;SRC;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent AHR;SRC GO:0007049| cell cycle SRC;AHR;CDK2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1;IL6 GO:0010033| response to organic substance CDK2;PTGS2 GO:0070301| cellular response to hydrogen peroxide IL6;ABL1 GO:0010628| positive regulation of gene expression SRC;IL6;MAP2K1 GO:0006915| apoptotic process ABL1;AHR GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0009636| response to toxin AHR;LYN GO:0031175| neuron projection development LYN;IL6 4891:[DB06616 DB08006] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0043065| positive regulation of apoptotic process DHODH;ABL1;SRC GO:0055114| oxidation-reduction process DHODH;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;SRC;DHODH;LYN 4892:[DB06616 DB06735] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06735|Enclomiphene CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 4893:[DB06616 DB01364] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0006260| DNA replication CDK2;ACHE GO:0042493| response to drug LYN;BCHE;SLC6A2;ABCB1;SRC;ADRA1A GO:0035556| intracellular signal transduction BCR;ADRA1A;SRC;LYN;CAMK2G GO:0007155| cell adhesion ABL1;HCK;SRC;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0008285| negative regulation of cell proliferation LYN;BCHE;ADRA1A;MAP2K1 GO:0009636| response to toxin SLC18A2;LYN GO:0008283| cell proliferation SRC;ACHE GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ADRA1A;ABL1 GO:0055085| transmembrane transport ABCB1;SLC18A2;SLC6A2 GO:0007165| signal transduction LYN;MAP2K1;SRC;ADRA1A;BCR GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0006810| transport ABCB1;SLC6A2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A 4894:[DB06616 DB03769] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03769|D-Eritadenine AHCY common genes common pathways 4895:[DB06616 DB04682] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 4896:[DB06616 DB07787] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07787|5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE PARP1 common genes common pathways GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PARP1 GO:0006281| DNA repair PARP1;CDK2;ABL1 GO:0006974| response to DNA damage stimulus ABL1;PARP1;CDK2;LYN GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PARP1 GO:1901216| PARP1;ABL1 GO:1900182| SRC;PARP1 GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:0006915| apoptotic process ABL1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;PARP1 4897:[DB06616 DB02426] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02426|Carboxyatractyloside SLC25A4 common genes common pathways GO:0016032| viral reproduction SLC25A4;LYN;HCK;SRC GO:0006810| transport SLC25A4;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC25A4 4898:[DB06616 DB06997] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MET;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;MET GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MET;MAP3K2;CAMK2G;LYN;CDK2 GO:0007165| signal transduction BCR;SRC;MAP2K1;MET;LYN GO:0008283| cell proliferation SRC;MET GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MET;LYN GO:0035635| entry of bacterium into host cell MET;SRC GO:0000165| MAPKKK cascade CAMK2G;MET;MAP2K1;MAP2K2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MET 4899:[DB06616 DB07966] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07966|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile SRC common genes SRC common pathways GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;BCR;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1 GO:0045785| positive regulation of cell adhesion SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0002376| immune system process SRC;HCK;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0031295| T cell costimulation LYN;SRC GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0071456| cellular response to hypoxia SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0048477| oogenesis SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction LYN;HCK;SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0038128| SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| ABL1;SRC;HCK;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2 GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0038083| LYN;ABL1;SRC;HCK GO:0042493| response to drug SRC;ABCB1;LYN GO:0034332| adherens junction organization SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0050900| leukocyte migration SRC;LYN GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0033625| positive regulation of integrin activation SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045087| innate immune response LYN;SRC;HCK;ABL1 GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0048008| platelet-derived growth factor receptor signaling pathway SRC;BCR;ABL1 GO:0045056| transcytosis SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;LYN GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0086098| SRC 4900:[DB06616 DB05464] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways GO:0050728| negative regulation of inflammatory response NFKB1;BCR GO:0006954| inflammatory response NFKB2;LYN;HCK;NFKB1 GO:0010629| negative regulation of gene expression NFKB1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;ABL1;NFKB2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;NFKB1;MAP3K2;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;CDK2;NFKB2 GO:0045087| innate immune response LYN;NFKB2;HCK;SRC;NFKB1;ABL1 GO:0071260| cellular response to mechanical stimulus NFKB1;MAP3K2 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;NFKB1 GO:0043066| negative regulation of apoptotic process HCK;SRC;NFKB1 GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC;NFKB1 GO:0032496| response to lipopolysaccharide NFKB2;BCR GO:0090263| positive regulation of canonical Wnt receptor signaling pathway NFKB1;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;NFKB1 GO:0006915| apoptotic process ABL1;NFKB1 GO:0038095| LYN;NFKB1 GO:0007165| signal transduction LYN;NFKB2;NFKB1;BCR;SRC;MAP2K1 GO:0048536| spleen development NFKB2;ABL1 4901:[DB06616 DB04381] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ALDH2;CYP2C8 4902:[DB06616 DB01644] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;GSR GO:0034599| cellular response to oxidative stress GSR;ABL1 4903:[DB06616 DB03991] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways GO:0006629| lipid metabolic process NEU2;CYP3A4 4904:[DB06616 DB08350] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes ABL1 common pathways GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0030182| neuron differentiation ABL1;MAP2K1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;LYN GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0045184| establishment of protein localization ABL1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0042100| B cell proliferation ABL1 GO:0002322| B cell proliferation involved in immune response ABL1 GO:0045580| regulation of T cell differentiation ABL1 GO:0006915| apoptotic process ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN GO:0009791| post-embryonic development ABL1 GO:1900272| ABL1 GO:1990051| ABL1 GO:0001922| B-1 B cell homeostasis ABL1 GO:0050853| B cell receptor signaling pathway LYN;ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0006464| protein modification process ABL1 GO:0046632| alpha-beta T cell differentiation ABL1 GO:0030100| regulation of endocytosis ABL1 GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:1903053| ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:0072358| cardiovascular system development ABL1 GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0001843| neural tube closure ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:0048538| thymus development ABL1;MAP2K1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0048536| spleen development ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:1900026| ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:0006979| response to oxidative stress ABL1 GO:1902715| ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:0007050| cell cycle arrest MAP2K1;ABL1 GO:0031113| regulation of microtubule polymerization ABL1 GO:1903351| ABL1 GO:0090135| actin filament branching ABL1 GO:1905555| ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:1900042| ABL1 GO:0038083| LYN;HCK;SRC;ABL1 GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0006909| phagocytosis HCK;ABL1 GO:0010506| regulation of autophagy ABL1 GO:1901216| ABL1 GO:1904531| ABL1 GO:0050885| neuromuscular process controlling balance ABL1;BCR GO:0006914| autophagy ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN GO:0000278| mitotic cell cycle ABL1 GO:0006298| mismatch repair ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization ABL1;HCK GO:0042770| signal transduction in response to DNA damage ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0030036| actin cytoskeleton organization ABL1;BCR GO:0038096| LYN;SRC;HCK;ABL1 GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 GO:1902036| ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:1905244| ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0030516| regulation of axon extension ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0038189| ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0043542| endothelial cell migration ABL1 GO:1904528| ABL1 GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0030035| microspike assembly ABL1 GO:0030155| regulation of cell adhesion ABL1 GO:0006897| endocytosis ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:2000145| regulation of cell motility ABL1 GO:1900275| ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:2000772| regulation of cellular senescence ABL1 GO:0007155| cell adhesion ABL1;HCK;SRC GO:0045087| innate immune response LYN;HCK;SRC;ABL1 GO:0048668| collateral sprouting ABL1 GO:0051882| mitochondrial depolarization ABL1 GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2 GO:0006281| DNA repair CDK2;ABL1 4905:[DB06616 DB08743] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0043542| endothelial cell migration DPP4;ABL1 GO:0007155| cell adhesion DPP4;ABL1;SRC;HCK GO:0008284| positive regulation of cell proliferation DPP4;CDK2;LYN;HCK GO:0031295| T cell costimulation SRC;LYN;DPP4 4906:[DB06616 DB05200] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05200|AT2220 GAA common genes common pathways GO:0050885| neuromuscular process controlling balance GAA;BCR;ABL1 4907:[DB06616 DB01472] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01472|4-Methoxyamphetamine SLC6A3;SLC6A4;SLC18A2;ADRA1A;ADRA2A;MAOA;MAOB;CYP2D6 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;LYN GO:0010033| response to organic substance SLC6A4;CDK2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010628| positive regulation of gene expression SLC6A4;MAP2K1;SRC GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0009791| post-embryonic development SLC18A2;ABL1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A3;SLC18A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;ADRA1A;MAP2K2;MAP2K1 GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0009636| response to toxin SLC6A4;MAOB;LYN;SLC18A2 GO:0007420| brain development BCR;SLC6A4 GO:0007165| signal transduction LYN;ADRA2A;MAP2K1;BCR;ADRA1A;SRC GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0030168| platelet activation LYN;SRC;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;MAOB;MAOA;CYP3A4 GO:0042493| response to drug SLC6A3;SLC6A4;ADRA1A;SRC;ABCB1;LYN;MAOB GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0032148| activation of protein kinase B activity SRC;ADRA2A GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;ADRA1A GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA2A;HCK GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0032496| response to lipopolysaccharide MAOB;BCR 4908:[DB06616 DB14707] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14707|Cemiplimab PDCD1 common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;PDCD1 GO:0043065| positive regulation of apoptotic process PDCD1;ABL1;SRC GO:0043066| negative regulation of apoptotic process PDCD1;HCK;SRC GO:0006915| apoptotic process PDCD1;ABL1 GO:0031295| T cell costimulation PDCD1;LYN;SRC GO:0007165| signal transduction LYN;PDCD1;MAP2K1;SRC;BCR GO:0002376| immune system process PDCD1;LYN;HCK;SRC 4909:[DB06616 DB12960] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12960|INCB-9471 CCR5 common genes common pathways GO:0006954| inflammatory response HCK;LYN;CCR5 GO:0016032| viral reproduction SRC;HCK;CCR5;LYN GO:0006816| calcium ion transport CCR5;CAMK2G GO:0000165| MAPKKK cascade CAMK2G;CCR5;MAP2K2;MAP2K1 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;CCR5 GO:0006935| chemotaxis CCR5;MAP2K1 GO:0007165| signal transduction LYN;CCR5;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCR5 4910:[DB06616 DB04953] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CDK2 GO:0014070| response to organic cyclic compound LYN;UGT1A1 GO:0055085| transmembrane transport KCNQ4;KCNQ3;KCNQ2;KCNQ5;ABCB1 GO:0006813| potassium ion transport KCNQ3;CDK2;KCNQ4;KCNQ5;KCNQ2 GO:0017144| drug metabolic process CYP2C8;UGT1A3;CYP3A4;UGT1A9;UGT1A1;UGT1A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0042493| response to drug LYN;UGT1A1;ABCB1;SRC GO:0006805| xenobiotic metabolic process CYP2C8;NAT2;UGT1A9;CYP3A4 GO:0007399| nervous system development KCNQ2;CAMK2G GO:0042472| inner ear morphogenesis KCNQ4;BCR GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;BCR 4911:[DB06616 DB09333] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09333|Iopodic acid DIO3;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DIO3 GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0006915| apoptotic process DIO3;ABL1 4912:[DB06616 DB11571] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11571|Human Thrombin F5;F8;F11;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0007596| blood coagulation F5;FGA;F11;FGB;F13A1;FGG;F13B;F8;LYN GO:2000352| negative regulation of endothelial cell apoptosis FGG;FGA;FGB;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGG;FGA;MAP2K1;SRC;FGB;MAP2K2;ABL1 GO:1900026| FGB;FGA;ABL1;FGG GO:0002376| immune system process HCK;FGA;FGB;SRC;LYN GO:0007165| signal transduction LYN;FGG;FGA;MAP2K1;SRC;FGB;BCR GO:0030168| platelet activation LYN;F8;FGG;SRC;FGB;FGA GO:0002250| adaptive immune response FGA;FGB;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;F8 GO:0002576| platelet degranulation LYN;FGG;F8;F13A1;FGA;F5;FGB GO:0045087| innate immune response HCK;FGA;FGB;SRC;ABL1;LYN 4913:[DB06616 DB06707] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;ADRA2B;MAP3K2 GO:0007165| signal transduction SRC;BCR;MAP2K1;ADRA2A;ADRA2C;ADRA2B;LYN GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0030168| platelet activation ADRA2C;LYN;ADRA2B;SRC;ADRA2A GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA2A;HCK GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2B;ADRA2C GO:0007265| Ras protein signal transduction ADRA2A;CDK2 4914:[DB06616 DB07602] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0046777| protein autophosphorylation LYN;CAMK2G;EGFR;HCK;SRC;BCR;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade EGFR;MAP2K1;SRC;MAP2K2;ABL1 GO:0014070| response to organic cyclic compound LYN;EGFR GO:0008283| cell proliferation EGFR;SRC GO:0070372| regulation of ERK1 and ERK2 cascade LYN;EGFR GO:0007165| signal transduction LYN;SRC;BCR;EGFR;MAP2K1 GO:0006979| response to oxidative stress EGFR;ABL1 GO:0000186| activation of MAPKK activity MAP3K2;EGFR GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;EGFR;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:1903800| EGFR;MAP2K1;MAP2K2 GO:0098609| EGFR;SRC GO:0030335| positive regulation of cell migration EGFR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;EGFR;HCK GO:0016310| phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;EGFR;CAMK2G;LYN;CDK2;MAP3K2 GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;EGFR;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC GO:0038128| SRC;EGFR GO:0001934| positive regulation of protein phosphorylation EGFR;ABL1;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;EGFR;MAP2K2;SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;EGFR;ABL1 GO:0038083| SRC;HCK;EGFR;ABL1;LYN GO:0071260| cellular response to mechanical stimulus EGFR;MAP3K2 GO:0035556| intracellular signal transduction BCR;SRC;EGFR;CAMK2G;LYN GO:2000145| regulation of cell motility EGFR;ABL1 GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;EGFR GO:0008284| positive regulation of cell proliferation HCK;EGFR;CDK2;LYN GO:0007275| multicellular organismal development CDK2;CAMK2G;EGFR GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;EGFR;ABL1;LYN GO:0042127| regulation of cell proliferation ABL1;SRC;EGFR 4915:[DB06616 DB12615] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12615|Plazomicin rpsN;rpsK;SLC47A1;SLC47A2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC47A1;SLC47A2 GO:0055085| transmembrane transport ABCB1;SLC47A1;SLC47A2 4916:[DB06616 DB08818] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08818|Hyaluronic acid CD44;ICAM1;HMMR;NCAN;VCAN;C1QBP;HAPLN1;HAPLN3;HAPLN4;HABP2;LAYN;STAB2;TNFAIP6;IMPG2;HABP4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;C1QBP;HABP4 GO:0042493| response to drug SRC;ABCB1;LYN;ICAM1 GO:0055114| oxidation-reduction process CYP3A4;STAB2;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CD44 GO:0050900| leukocyte migration ICAM1;LYN;CD44;SRC GO:0016032| viral reproduction SRC;HCK;LYN;C1QBP;ICAM1 GO:0050728| negative regulation of inflammatory response TNFAIP6;BCR GO:0006954| inflammatory response TNFAIP6;HCK;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;C1QBP GO:0002250| adaptive immune response LYN;C1QBP GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;HMMR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ICAM1;CD44;LYN;SRC;ABL1 GO:0030838| positive regulation of actin filament polymerization ICAM1;HCK GO:0032496| response to lipopolysaccharide BCR;ICAM1 GO:0007275| multicellular organismal development CDK2;CAMK2G;VCAN GO:0030155| regulation of cell adhesion ICAM1;ABL1 GO:0043066| negative regulation of apoptotic process CD44;SRC;HCK GO:0006897| endocytosis STAB2;ABL1 GO:0071222| cellular response to lipopolysaccharide ICAM1;ABL1;BCR;SRC GO:0002576| platelet degranulation HABP4;LYN GO:0043065| positive regulation of apoptotic process C1QBP;ABL1;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;HABP4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;C1QBP GO:0007155| cell adhesion HAPLN1;HAPLN4;CD44;VCAN;HAPLN3;STAB2;HABP2;ICAM1;ABL1;SRC;TNFAIP6;HCK;NCAN GO:0045087| innate immune response LYN;C1QBP;ABL1;HCK;SRC GO:0008360| regulation of cell shape ICAM1;HCK GO:0014070| response to organic cyclic compound LYN;ICAM1 GO:0043200| response to amino acid stimulus LYN;ICAM1 GO:2000352| negative regulation of endothelial cell apoptosis ICAM1;ABL1 GO:0006915| apoptotic process ABL1;C1QBP GO:0070374| positive regulation of ERK1 and ERK2 cascade CD44;ICAM1;ABL1;SRC;MAP2K2;MAP2K1 GO:0045785| positive regulation of cell adhesion SRC;C1QBP GO:0032868| response to insulin stimulus ICAM1;LYN GO:0043547| positive regulation of GTPase activity ICAM1;BCR GO:0098609| SRC;CD44;ICAM1 GO:0030335| positive regulation of cell migration LYN;TNFAIP6 GO:0007417| central nervous system development HAPLN1;LYN;HAPLN4;HAPLN3;VCAN;SRC;NCAN GO:0071456| cellular response to hypoxia SRC;ICAM1 GO:1900026| C1QBP;ABL1 GO:0060333| interferon-gamma-mediated signaling pathway HCK;CAMK2G;CD44;ICAM1 GO:0002376| immune system process C1QBP;LYN;HCK;SRC GO:0007165| signal transduction BCR;TNFAIP6;SRC;MAP2K1;LYN 4917:[DB06616 DB07609] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6 4918:[DB06616 DB03323] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03323|Maltose AMY2B;aglA common genes common pathways 4919:[DB06616 DB04617] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways GO:0006260| DNA replication ACHE;CDK2 GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0007399| nervous system development ACHE;CAMK2G GO:0008283| cell proliferation SRC;ACHE 4920:[DB06616 DB00576] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0002576| platelet degranulation LYN;ALB GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0097267| CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 4921:[DB06616 DB01213] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2A6;CYP2E1;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6;ADH1A;CYP2C8 GO:0070542| response to fatty acid SRC;CAT GO:0006979| response to oxidative stress ABL1;CAT GO:0032868| response to insulin stimulus LYN;CAT GO:0009636| response to toxin LYN;CAT GO:0034599| cellular response to oxidative stress ABL1;CAT GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0042542| response to hydrogen peroxide CAT;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;CAT GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process ADH1A;ADH1B;CYP3A4;CYP2E1;CYP2A6;CAT;CYP2C8;ADH1C GO:0042738| exogenous drug catabolic process CYP2C8;CYP2A6;CYP3A4 GO:0042493| response to drug CAT;SRC;ABCB1;LYN;CYP2E1 4922:[DB06616 DB00718] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0016310| phosphorylation CAMK2G;LYN;CDK2;AK2;MAP3K2;AK4;NME2;ABL1;NME1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0006810| transport ABCC5;ABCB1 GO:0030154| cell differentiation CAMK2G;HCK;NME1 GO:0007229| integrin-mediated signaling pathway ABL1;NME2;SRC;HCK GO:0007420| brain development AK4;BCR GO:0014070| response to organic cyclic compound ABCC4;LYN GO:0006855| drug transmembrane transport SLC22A3;ABCB1 GO:0055085| transmembrane transport ABCC5;ABCB1;ABCC4;SLC22A3;SLC22A6 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;NME1 GO:0010033| response to organic substance ABCC4;CDK2 GO:0071398| cellular response to fatty acid SRC;NME1 GO:0006897| endocytosis NME1;ABL1 GO:0043066| negative regulation of apoptotic process NME2;SRC;HCK GO:0002576| platelet degranulation ABCC4;LYN GO:0007155| cell adhesion HCK;SRC;ABL1;NME2 GO:0007399| nervous system development NME1;CAMK2G GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;NME1;MAP3K2 GO:0010629| negative regulation of gene expression NME1;MAP2K2;MAP2K1 GO:0042493| response to drug LYN;AK4;NME1;SRC;ABCB1;ABCC4 GO:0006355| regulation of transcription, DNA-dependent NME2;ABL1 GO:0055114| oxidation-reduction process ABCC4;CYP2C8;CYP3A4 GO:0002762| negative regulation of myeloid leukocyte differentiation LYN;NME1 GO:0010976| positive regulation of neuron projection development LYN;NME1 4923:[DB06616 DB04463] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04463|3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol CBR1;CBR1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CBR1 GO:0017144| drug metabolic process CBR1;CYP2C8;CYP3A4 4924:[DB06616 DB00368] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0007165| signal transduction ADRA2C;ADRB2;LYN;ADRA2B;ADRA1D;ADRA1B;ADRA2A;ADRB3;BCR;ADRA1A;SRC;ADRB1;MAP2K1 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0045453| bone resorption ADRB2;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1B;ADRA1A;ADRA1D GO:0006810| transport SLC6A2;ABCB1 GO:0030168| platelet activation SRC;ADRA2A;ADRA2B;LYN;ADRA2C GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;LYN GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC22A3;SLC18A1;SLC22A1;SLC22A5 GO:0055085| transmembrane transport SLC22A1;SLC6A2;SLC18A1;SLC22A3;SLC22A5;SLC18A2;ABCB1;SLC22A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;ADRA1A;MAP2K2;ABL1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0008283| cell proliferation ADRA1B;SRC;ADRA1D GO:0009636| response to toxin LYN;SLC18A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;POU5F1 GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2B;ADRA2C GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;CDK2;LYN;ADRA1D GO:0035556| intracellular signal transduction BCR;SRC;ADRA1A;ADRA1B;LYN;CAMK2G GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0007275| multicellular organismal development ADRA1D;CDK2;CAMK2G;POU5F1;ADRA1B GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0055114| oxidation-reduction process PAH;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ADRA1A;ABCB1;LYN;SLC6A2 GO:0006355| regulation of transcription, DNA-dependent ABL1;POU5F1 4925:[DB06616 DB04759] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04759|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways 4926:[DB06616 DB08238] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;SRC GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;FGF1;CAMK2G GO:0001934| positive regulation of protein phosphorylation ABL1;FGF1;LYN GO:0032148| activation of protein kinase B activity SRC;FGF1 GO:0008284| positive regulation of cell proliferation FGF1;LYN;CDK2;HCK GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;FGF1 GO:0007275| multicellular organismal development FGF1;CAMK2G;CDK2 GO:0043406| positive regulation of MAP kinase activity FGF1;SRC GO:0000187| activation of MAPK activity FGF1;MAP3K2;MAP2K2;MAP2K1 GO:0008283| cell proliferation SRC;FGF1 GO:1902533| SRC;FGF1 GO:0007165| signal transduction FGF1;LYN;BCR;SRC;MAP2K1 GO:0030154| cell differentiation HCK;CAMK2G;FGF1 GO:0034605| cellular response to heat LYN;FGF1 GO:0030335| positive regulation of cell migration LYN;FGF1 GO:0010595| positive regulation of endothelial cell migration ABL1;FGF1 4927:[DB06616 DB03535] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03535|Z-Pro-Prolinal PREP common genes common pathways 4928:[DB06616 DB00151] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GCLM;SRC;GCLC GO:0043200| response to amino acid stimulus GSS;CDO1;LYN GO:0009636| response to toxin LYN;MGMT GO:0014070| response to organic cyclic compound LYN;MGMT GO:0045892| negative regulation of transcription, DNA-dependent SRC;GCLC GO:0032869| cellular response to insulin stimulus GCLC;GOT1;SRC GO:0009725| response to hormone stimulus LYN;GCLC GO:0070555| response to interleukin-1 SRC;GCLC GO:0006979| response to oxidative stress GCLM;GCLC;ABL1;GSS GO:0055114| oxidation-reduction process CYP2C8;CBS;CDO1;CYP3A4 GO:0042493| response to drug SRC;ABCB1;LYN;MGMT;GCLM GO:0031667| response to nutrient levels GSS;SRC GO:0006954| inflammatory response HCK;CDO1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;ABL1 GO:0034599| cellular response to oxidative stress ABL1;MGMT GO:0007399| nervous system development CAMK2G;GSS GO:0006281| DNA repair MGMT;CDK2;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;GCLC GO:0006974| response to DNA damage stimulus MGMT;CDK2;LYN;ABL1 GO:0043066| negative regulation of apoptotic process GCLC;HCK;SRC;MGMT;CTH 4929:[DB06616 DB02751] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02751|Glycocyamine GAMT common genes common pathways 4930:[DB06616 DB03185] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 4931:[DB06616 DB03453] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways GO:0065009| regulation of molecular function CAMK2G;IL2 GO:0002376| immune system process LYN;IL2;SRC;HCK GO:0007204| elevation of cytosolic calcium ion concentration ABL1;IL2 GO:0007155| cell adhesion HCK;SRC;IL2;ABL1 GO:0008284| positive regulation of cell proliferation IL2;HCK;LYN;CDK2 GO:0043066| negative regulation of apoptotic process IL2;HCK;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL2 GO:0001933| negative regulation of protein phosphorylation LYN;IL2 GO:0002250| adaptive immune response LYN;IL2 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;IL2;CAMK2G GO:0050728| negative regulation of inflammatory response BCR;IL2 GO:0001934| positive regulation of protein phosphorylation ABL1;IL2;LYN 4932:[DB06616 DB09292] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09292|Sacubitril MME;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 4933:[DB06616 DB08024] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;DPP4;LYN;CDK2 GO:0007155| cell adhesion DPP4;SRC;HCK;ABL1 GO:0043542| endothelial cell migration DPP4;ABL1 GO:0031295| T cell costimulation LYN;DPP4;SRC 4934:[DB06616 DB09038] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09038|Empagliflozin SLC5A2 common genes common pathways GO:0006810| transport ABCB1;SLC5A2 GO:0055085| transmembrane transport ABCB1;SLC5A2 4935:[DB06616 DB07586] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;HDAC8 GO:0006355| regulation of transcription, DNA-dependent HDAC8;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;HDAC8 4936:[DB06616 DB03516] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0017144| drug metabolic process CYP2C8;AOX1;CYP3A4 GO:0001933| negative regulation of protein phosphorylation XDH;LYN GO:0055114| oxidation-reduction process DPYD;CYP2C8;XDH;AOX1;CYP3A4 GO:0010629| negative regulation of gene expression XDH;MAP2K2;MAP2K1 4937:[DB06616 DB00749] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4;CYP2C9 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;RXRA GO:0042493| response to drug ABCB1;SRC;PTGS2;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;RXRA;MAP2K2;SRC;MAP2K1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS1;HCK;PTGS2;LYN GO:0016032| viral reproduction HCK;SRC;LYN;RXRA GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC;ABL1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0007507| heart development RXRA;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;CDK2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2;UGT2B7;PTGS1 GO:0008284| positive regulation of cell proliferation HCK;PTGS2;CDK2;LYN GO:0002576| platelet degranulation ALB;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043066| negative regulation of apoptotic process PTGS2;ALB;HCK;SRC GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;UGT1A9;CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT2B7;CYP2C8 GO:0017144| drug metabolic process UGT1A9;UGT1A10;CYP3A4;CYP2C9;UGT1A3;CYP2C8 GO:0097267| CYP2C9;CYP2C8 GO:0070542| response to fatty acid PTGS2;SRC GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 4938:[DB06616 DB07330] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07330|trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium PARP1 common genes common pathways GO:0006915| apoptotic process ABL1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:1900182| PARP1;SRC GO:1901216| ABL1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:0034599| cellular response to oxidative stress ABL1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0006281| DNA repair CDK2;PARP1;ABL1 GO:0006974| response to DNA damage stimulus ABL1;PARP1;CDK2;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 4939:[DB06616 DB03128] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0007165| signal transduction CHRM4;MAP2K1;SRC;BCR;CHRNA7;CHRM3;CHRM2;LYN;CHRM1 GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;CHRNA7;MAP3K2 GO:0006855| drug transmembrane transport SLC22A5;SLC22A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A5;SLC22A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;ABL1;MAP2K1;MAP2K2;SRC GO:0008283| cell proliferation CHRM3;ACHE;CHRM1;CHRM4;SRC GO:0007155| cell adhesion SRC;HCK;ABL1;ACHE GO:0007399| nervous system development CHRM3;ACHE;CHRM2;CHRM1;CAMK2G GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;CHRM1;LYN;CDK2 GO:0006260| DNA replication CDK2;ACHE GO:0006816| calcium ion transport CHRNA7;CAMK2G GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1;LYN 4940:[DB06616 DB08888] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08888|Ocriplasmin FN1;A2M;SERPINF2 common genes common pathways GO:0008360| regulation of cell shape FN1;HCK GO:0045597| positive regulation of cell differentiation MAP2K1;SERPINF2 GO:0007155| cell adhesion FN1;ABL1;SRC;HCK GO:0002576| platelet degranulation A2M;SERPINF2;FN1;LYN GO:0008284| positive regulation of cell proliferation HCK;FN1;LYN;CDK2 GO:0001932| regulation of protein phosphorylation MAP2K1;LYN;FN1 GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1;FN1 GO:0050900| leukocyte migration SRC;FN1;LYN GO:0070372| regulation of ERK1 and ERK2 cascade FN1;LYN GO:0051056| regulation of small GTPase mediated signal transduction BCR;A2M GO:0043547| positive regulation of GTPase activity BCR;A2M GO:0010033| response to organic substance SERPINF2;CDK2 GO:0010628| positive regulation of gene expression FN1;MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SERPINF2;SRC;MAP2K2;ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1;SERPINF2 4941:[DB06616 DB03824] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03824|7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline PNMT common genes common pathways 4942:[DB06616 DB01306] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01306|Insulin Aspart INSR common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;INSR;LYN GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;INSR GO:0035556| intracellular signal transduction SRC;BCR;INSR;LYN;CAMK2G GO:0032148| activation of protein kinase B activity SRC;INSR GO:0038083| LYN;INSR;ABL1;HCK;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;INSR;SRC;MAP2K2;MAP2K1 GO:0023014| signal transduction via phosphorylation event INSR;LYN GO:0001934| positive regulation of protein phosphorylation LYN;INSR;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;SRC GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;INSR GO:0030335| positive regulation of cell migration LYN;INSR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway INSR;LYN;HCK GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;INSR;MAP3K2;LYN;CDK2;CAMK2G GO:0032869| cellular response to insulin stimulus INSR;SRC GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;INSR GO:0046777| protein autophosphorylation LYN;CAMK2G;INSR;ABL1;HCK;BCR;SRC 4943:[DB06616 DB02198] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C8 GO:0006954| inflammatory response LYN;PTGS1;HCK GO:0006979| response to oxidative stress ABL1;PTGS1 4944:[DB06616 DB00148] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport SLC22A5;SLC6A8;ABCB1 GO:0016310| phosphorylation ABL1;CKMT2;CKB;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CKM;LYN;CDK2;CKMT1A;MAP3K2 GO:0006810| transport SLC6A8;ABCB1 GO:0007420| brain development CKB;BCR 4945:[DB06616 DB07780] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways GO:0007165| signal transduction MAP2K1;KRAS;SRC;BCR;LYN GO:0008202| steroid metabolic process FDPS;CYP2C8;CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;KRAS;SRC GO:0006464| protein modification process RABGGTB;RABGGTA;ABL1 GO:0007411| axon guidance KRAS;SRC GO:0043406| positive regulation of MAP kinase activity SRC;KRAS GO:0038095| LYN;KRAS GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FNTA GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;KRAS GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042981| regulation of apoptotic process RABGGTB;MAP3K2;RABGGTA;MAP2K2;MAP2K1 GO:0051385| response to mineralocorticoid stimulus KRAS;SRC GO:0042127| regulation of cell proliferation SRC;ABL1;FNTB GO:0007265| Ras protein signal transduction KRAS;CDK2 GO:0002223| stimulatory C-type lectin receptor signaling pathway KRAS;SRC;LYN GO:0016032| viral reproduction FDPS;HCK;SRC;LYN GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2;KRAS GO:0019221| cytokine-mediated signaling pathway KRAS;HCK GO:0038128| SRC;KRAS GO:0030036| actin cytoskeleton organization ABL1;BCR;KRAS GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;KRAS GO:0001934| positive regulation of protein phosphorylation LYN;KRAS;ABL1 GO:0050900| leukocyte migration LYN;KRAS;SRC 4946:[DB06616 DB08053] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08053|1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes SRC common pathways GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0071456| cellular response to hypoxia SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0036035| osteoclast development SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0048477| oogenesis SRC GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0031295| T cell costimulation SRC;LYN GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process LYN;SRC;HCK GO:0045453| bone resorption SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;BCR;SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;LYN GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0086098| SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0045056| transcytosis SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0033625| positive regulation of integrin activation SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response LYN;HCK;SRC;ABL1 GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;BCR GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0034332| adherens junction organization SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0050900| leukocyte migration SRC;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0038083| SRC;HCK;ABL1;LYN GO:0042493| response to drug LYN;ABCB1;SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:0038128| SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| ABL1;HCK;SRC;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction HCK;SRC;LYN 4947:[DB06616 DB06090] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06090|Bradanicline CHRNA7 common genes common pathways GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRNA7;HCK GO:0006816| calcium ion transport CAMK2G;CHRNA7 GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7;ABL1 GO:0007165| signal transduction LYN;CHRNA7;MAP2K1;SRC;BCR GO:0000187| activation of MAPK activity CHRNA7;MAP2K2;MAP2K1;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;CHRNA7 4948:[DB06616 DB01614] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K2;ADRA1A;SRC;DRD2;MAP2K1;ABL1 GO:0009636| response to toxin DRD2;LYN GO:0008283| cell proliferation ADRA1B;SRC;HTR1A GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;MAP2K1;LYN GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression DRD1;SRC;MAP2K1 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ADRA1A;ABL1;ADRA1B GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0030900| forebrain development SRC;DRD2 GO:1903351| ABL1;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0007165| signal transduction SRC;DRD2;ADRA1A;BCR;MAP2K1;ADRA1B;DRD1;HTR1A;LYN;HTR2A GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0042493| response to drug DRD1;ABCB1;SRC;DRD2;ADRA1A;HTR2A;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;HTR2A;LYN GO:0016032| viral reproduction SRC;HCK;HTR2A;LYN GO:0007275| multicellular organismal development CAMK2G;CDK2;ADRA1B GO:0048678| response to axon injury DRD2;LYN GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0035556| intracellular signal transduction BCR;DRD2;SRC;ADRA1A;ADRA1B;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0002576| platelet degranulation ALB;LYN GO:0008284| positive regulation of cell proliferation HCK;HTR2A;CDK2;LYN;HTR1A 4949:[DB06616 DB13151] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0031667| response to nutrient levels F7;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;F8 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;F2 GO:0050900| leukocyte migration F2;SRC;LYN GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC;F7 GO:0002250| adaptive immune response FGA;FGB;LYN GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC GO:0007275| multicellular organismal development F2;CAMK2G;CDK2 GO:0008284| positive regulation of cell proliferation HCK;F2;CDK2;LYN GO:0002576| platelet degranulation LYN;F8;F13A1;FGB;FGA;F5 GO:0045087| innate immune response ABL1;FGA;HCK;SRC;FGB;LYN GO:0008360| regulation of cell shape HCK;F2 GO:0014070| response to organic cyclic compound F7;LYN GO:2000352| negative regulation of endothelial cell apoptosis FGB;FGA;ABL1 GO:0007596| blood coagulation F13A1;F7;F2;F5;FGA;FGB;LYN;F10;F9;F8 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;FGB;MAP2K2;FGA;MAP2K1;ABL1 GO:0030335| positive regulation of cell migration F7;LYN;F10 GO:0030168| platelet activation LYN;F8;SRC;FGB;FGA;F2 GO:1900026| ABL1;FGB;FGA GO:0002376| immune system process HCK;FGA;FGB;SRC;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;F2 GO:1900182| SRC;F2 GO:0009725| response to hormone stimulus F7;LYN GO:0007165| signal transduction LYN;MAP2K1;FGA;BCR;FGB;SRC 4950:[DB06616 DB01610] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways GO:0055085| transmembrane transport SLC15A1;SLC15A2;ABCB1;SLC6A14 GO:0009636| response to toxin SLC6A14;LYN GO:0006810| transport SLC15A1;SLC15A2;SLC6A14;ABCB1 4951:[DB06616 DB11914] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11914|Lebrikizumab IL13;IL13 common genes common pathways GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL13;LYN GO:0032496| response to lipopolysaccharide BCR;IL13 GO:0071260| cellular response to mechanical stimulus MAP3K2;IL13 GO:0009612| response to mechanical stimulus IL13;SRC GO:0006954| inflammatory response IL13;HCK;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;IL13 GO:2000352| negative regulation of endothelial cell apoptosis IL13;ABL1 4952:[DB06616 DB01382] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0042493| response to drug ABCC8;LYN;SRC;ABCB1 GO:0032496| response to lipopolysaccharide ABCC8;BCR GO:0055085| transmembrane transport ABCC8;ABCB1 GO:0032868| response to insulin stimulus ABCC8;LYN GO:0006813| potassium ion transport KCNJ1;CDK2;ABCC8 GO:0007165| signal transduction ABCC8;LYN;MAP2K1;SRC;BCR 4953:[DB06616 DB07448] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07448|(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid LAP3 common genes common pathways 4954:[DB06616 DB03279] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03279|Dodecyl-Alpha-D-Maltoside RARG common genes common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1;RARG GO:0008285| negative regulation of cell proliferation RARG;MAP2K1;LYN GO:0001843| neural tube closure RARG;ABL1 GO:0060324| face development MAP2K1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;ABL1 GO:0071300| cellular response to retinoic acid LYN;RARG GO:0043066| negative regulation of apoptotic process RARG;HCK;SRC GO:0043065| positive regulation of apoptotic process SRC;RARG;ABL1 GO:0008284| positive regulation of cell proliferation HCK;RARG;LYN;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;CDK2 4955:[DB06616 DB08836] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0006810| transport ABCB1;SLC15A1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLCO1A2 4956:[DB06616 DB00165] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00165|Pyridoxine PDXK;CYP1A1 common genes common pathways GO:0010033| response to organic substance CDK2;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0008283| cell proliferation CYP1A1;SRC;PDXK GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0009636| response to toxin CYP1A1;LYN GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0017144| drug metabolic process CYP2C8;CYP1A1;CYP3A4 GO:0097267| CYP1A1;CYP2C8 GO:0016310| phosphorylation PDXK;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2C8 GO:0042493| response to drug SRC;ABCB1;CYP1A1;LYN GO:0009615| response to virus CYP1A1;SRC GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;BCR 4957:[DB06616 DB00714] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;HTR2B;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0030335| positive regulation of cell migration DRD1;ADRA2A;LYN GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0030168| platelet activation ADRA2A;SRC;ADRA2C;LYN;ADRA2B GO:0050715| positive regulation of cytokine secretion SRC;HTR2B GO:0007165| signal transduction HTR1D;HTR1A;DRD4;ADRA2C;HTR2A;ADRA2B;LYN;DRD3;BCR;HTR1B;DRD2;SRC;MAP2K1;DRD5;HTR2C;HTR2B;ADRA2A;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:1903351| DRD1;ABL1 GO:0030900| forebrain development DRD2;SRC GO:0008283| cell proliferation HTR1A;SRC GO:0009636| response to toxin DRD2;LYN;HTR1D GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;SRC;MAP2K2;MAP2K1;ABL1;HTR2B;HTR2C;HTR2A GO:0000187| activation of MAPK activity ADRA2B;DRD4;MAP3K2;MAP2K1;MAP2K2 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0010628| positive regulation of gene expression DRD1;MAP2K1;SRC GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC;HTR2B;ADRA2A GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0001932| regulation of protein phosphorylation MAP2K1;DRD1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;HTR2B GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0048678| response to axon injury DRD2;LYN GO:0008284| positive regulation of cell proliferation ADRA2A;HTR2B;HCK;HTR1A;DRD3;HTR2A;LYN;CDK2 GO:0043066| negative regulation of apoptotic process HTR2B;SRC;HCK GO:0006897| endocytosis ABL1;CALY GO:0035556| intracellular signal transduction CAMK2G;LYN;DRD2;SRC;BCR GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;SRC;ADRA2A GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0007507| heart development MAP2K1;HTR2B GO:0042493| response to drug HTR2C;HTR2B;DRD1;ABCB1;HTR1B;SRC;DRD2;DRD3;HTR2A;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;HTR2B GO:0016032| viral reproduction LYN;HTR2A;HCK;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;HTR2A GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR 4958:[DB06616 DB03495] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03495|4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose AMY2A;AMY2A common genes common pathways 4959:[DB06616 DB01600] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0042493| response to drug ABCB1;SRC;PTGS2;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0008284| positive regulation of cell proliferation PTGS2;LYN;CDK2;HCK GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 4960:[DB06616 DB03223] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03223|Diphthamide EEF2 common genes common pathways GO:0042493| response to drug LYN;EEF2;ABCB1;SRC GO:0042542| response to hydrogen peroxide SRC;EEF2 4961:[DB06616 DB06843] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways GO:0050885| neuromuscular process controlling balance BCR;ADCY5;ABL1 GO:0042493| response to drug SRC;ABCB1;GNAS;LYN GO:0035556| intracellular signal transduction ADCY5;BCR;ADCY2;SRC;CAMK2G;LYN GO:0009791| post-embryonic development GNAS;ABL1 GO:0007165| signal transduction LYN;MAP2K1;GNAS;BCR;SRC;ADCY2 GO:0007204| elevation of cytosolic calcium ion concentration ADCY5;ABL1 4962:[DB06616 DB08675] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways GO:0050728| negative regulation of inflammatory response BCR;PTGIS GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGIS GO:0006629| lipid metabolic process PTGIS;CYP3A4 GO:0071456| cellular response to hypoxia PTGIS;SRC 4963:[DB06616 DB00926] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00926|Etretinate RARA;RXRA;RARB;RXRG;RXRB;RARG;CYP19A1;CYP26A1;CRABP1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP26A1;CYP3A4;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CDK2;MAP3K2;SRC;MAP2K2;RARA;MAP2K1 GO:0010629| negative regulation of gene expression RARA;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent RXRA;RXRB;RARG;RXRG;ABL1;RARB;RARA GO:0016032| viral reproduction LYN;RXRA;SRC;HCK GO:0060324| face development RARG;MAP2K1;RARA GO:0007275| multicellular organismal development CRABP1;CDK2;CAMK2G GO:0007507| heart development MAP2K1;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RXRA;RARA;RARB;RARG GO:0042981| regulation of apoptotic process MAP2K2;RARA;MAP2K1;MAP3K2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP26A1;CYP2C8 GO:0071300| cellular response to retinoic acid RARA;RARG;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;RARB;RARA;RARG GO:0060065| uterus development CYP19A1;SRC GO:0043065| positive regulation of apoptotic process RARB;SRC;RARG;ABL1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;RARG;HCK;RARB;RARA GO:0071222| cellular response to lipopolysaccharide BCR;SRC;RARA;ABL1 GO:0008285| negative regulation of cell proliferation RARB;RARA;MAP2K1;RARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;RARA GO:0010628| positive regulation of gene expression RARG;SRC;MAP2K1;RARA GO:0001843| neural tube closure RARG;ABL1;RARA GO:0006468| protein phosphorylation ABL1;MAP2K1;RARA;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0007165| signal transduction LYN;CRABP1;RARB;MAP2K1;RARA;SRC;BCR 4964:[DB06616 DB11611] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11611|Lifitegrast ITGAL;CYP2C9;SLCO1A2;SLCO2B1 common genes common pathways GO:0006954| inflammatory response HCK;LYN;ITGAL GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0006909| phagocytosis ITGAL;ABL1;HCK GO:0050900| leukocyte migration SRC;ITGAL;LYN GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0007155| cell adhesion ITGAL;HCK;SRC;ABL1 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006928| cellular component movement MAP2K1;ITGAL GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLCO2B1 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ITGAL GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0098609| SRC;ITGAL GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0007229| integrin-mediated signaling pathway ITGAL;HCK;SRC;ABL1 4965:[DB06616 DB06699] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06699|Degarelix GNRHR common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;GNRHR;LYN GO:0007275| multicellular organismal development GNRHR;CAMK2G;CDK2 4966:[DB06616 DB05687] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CDK2;LYN;HCK GO:0035556| intracellular signal transduction SRC;DRD2;BCR;LYN;CAMK2G GO:0048678| response to axon injury LYN;DRD2 GO:0016032| viral reproduction HCK;SRC;LYN;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0042493| response to drug ABCB1;DRD2;SRC;HTR2A;LYN GO:0007165| signal transduction MAP2K1;BCR;SRC;DRD2;LYN;HTR2A GO:0030900| forebrain development SRC;DRD2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0030336| negative regulation of cell migration DRD2;BCR GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0009636| response to toxin DRD2;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;ABL1;DRD2;SRC;MAP2K2;MAP2K1 4967:[DB06616 DB03314] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03314|Fluorotryptophane TPI1;GSTM1 common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;TPI1 4968:[DB06616 DB01400] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01400|Neostigmine ACHE;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0008283| cell proliferation ACHE;SRC GO:0006260| DNA replication ACHE;CDK2 GO:0042493| response to drug ABCB1;SRC;LYN;BCHE GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 4969:[DB06616 DB04972] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04972|Canfosfamide GSTP1 common genes common pathways GO:0031667| response to nutrient levels SRC;GSTP1 GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;HCK;SRC GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;GSTP1 GO:0071222| cellular response to lipopolysaccharide GSTP1;BCR;SRC;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ABL1 GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:0009636| response to toxin GSTP1;LYN GO:0043200| response to amino acid stimulus LYN;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;GSTP1;MAP2K2 GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN GO:0007417| central nervous system development GSTP1;SRC;LYN GO:0032869| cellular response to insulin stimulus SRC;GSTP1 4970:[DB06616 DB04774] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04774|Reidispongiolide A ACTA1 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;ACTA1;SRC GO:0009612| response to mechanical stimulus ACTA1;SRC 4971:[DB06616 DB00200] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0006897| endocytosis ABL1;CUBN GO:0071732| cellular response to nitric oxide MTR;CDK2 GO:0006629| lipid metabolic process CYP3A4;CUBN GO:0007399| nervous system development CAMK2G;MTR GO:0007275| multicellular organismal development CAMK2G;AMN;CDK2 GO:0048678| response to axon injury LYN;MTR GO:0055114| oxidation-reduction process MMACHC;CYP2C8;MTRR;CYP3A4 GO:0043547| positive regulation of GTPase activity MUT;BCR GO:0008202| steroid metabolic process CUBN;CYP2C8;CYP3A4 GO:0042359| vitamin D metabolic process CUBN;CYP3A4 GO:0009791| post-embryonic development ABL1;MUT 4972:[DB06616 DB05578] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05578|Ramucirumab KDR common genes common pathways GO:0008360| regulation of cell shape HCK;KDR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;KDR GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process KDR;HCK;SRC GO:0007275| multicellular organismal development KDR;CAMK2G;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;KDR;SRC;MAP2K2;BCR;ABL1;LYN GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0016032| viral reproduction SRC;HCK;KDR;LYN GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;KDR GO:0038083| LYN;SRC;KDR;HCK;ABL1 GO:0006468| protein phosphorylation ABL1;MAP2K1;KDR;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0030154| cell differentiation HCK;KDR;CAMK2G GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;KDR;MAP2K1;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0030335| positive regulation of cell migration LYN;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;KDR GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;KDR;HCK;BCR;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;KDR;MAP2K1;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 4973:[DB06616 DB07187] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07187|6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;AKR1B1 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 4974:[DB06616 DB03974] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03974|L-Homoarginine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 GO:0043542| endothelial cell migration NOS3;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;NOS3;HCK GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;LYN 4975:[DB06616 DB09564] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09564|Insulin Degludec INSR common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation LYN;INSR;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;INSR GO:0035556| intracellular signal transduction INSR;CAMK2G;LYN;BCR;SRC GO:0032148| activation of protein kinase B activity INSR;SRC GO:0038083| ABL1;SRC;HCK;LYN;INSR GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;INSR;MAP3K2 GO:0023014| signal transduction via phosphorylation event LYN;INSR GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;SRC GO:0016310| phosphorylation INSR;MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0030335| positive regulation of cell migration INSR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;INSR GO:0006468| protein phosphorylation INSR;MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0032869| cellular response to insulin stimulus SRC;INSR GO:0000187| activation of MAPK activity MAP3K2;INSR;MAP2K1;MAP2K2 GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN;INSR 4976:[DB06616 DB03476] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03476|Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine PLAU common genes common pathways GO:0006935| chemotaxis MAP2K1;PLAU GO:0042127| regulation of cell proliferation SRC;ABL1;PLAU GO:0007165| signal transduction LYN;PLAU;MAP2K1;SRC;BCR GO:0030335| positive regulation of cell migration PLAU;LYN GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007596| blood coagulation LYN;PLAU 4977:[DB06616 DB02633] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02633|Cibacron Blue NQO1;GSTP1 common genes common pathways GO:0006979| response to oxidative stress ABL1;NQO1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0007417| central nervous system development LYN;GSTP1;SRC GO:0032869| cellular response to insulin stimulus GSTP1;SRC GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:0070301| cellular response to hydrogen peroxide ABL1;NQO1 GO:0014070| response to organic cyclic compound NQO1;LYN GO:0009636| response to toxin GSTP1;NQO1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;ABL1;LYN GO:0043200| response to amino acid stimulus GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1;GSTP1 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP3A4;CYP2C8;GSTP1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ABL1 GO:0034599| cellular response to oxidative stress GSTP1;ABL1 GO:0051602| response to electrical stimulus SRC;NQO1 GO:0031667| response to nutrient levels SRC;GSTP1 GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0055114| oxidation-reduction process CYP3A4;NQO1;CYP2C8 4978:[DB06616 DB08166] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08166|(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile PIM1 common genes common pathways GO:0008283| cell proliferation PIM1;SRC GO:0006915| apoptotic process ABL1;PIM1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;PIM1;CAMK2G;LYN GO:0007049| cell cycle CDK2;PIM1;SRC GO:0016310| phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2;PIM1 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MAP3K2;PIM1 GO:0007346| regulation of mitotic cell cycle PIM1;MAP3K2;MAP2K2;MAP2K1 GO:0007275| multicellular organismal development CAMK2G;CDK2;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;SRC;HCK 4979:[DB06616 DB06931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 4980:[DB06616 DB01289] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0032496| response to lipopolysaccharide KCNJ8;BCR GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0007507| heart development MAP2K1;KCNJ8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0006813| potassium ion transport CDK2;KCNJ8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 4981:[DB06616 DB08176] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08176|(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE MAOB common genes common pathways GO:0042493| response to drug LYN;MAOB;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOB GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0009636| response to toxin MAOB;LYN 4982:[DB06616 DB13144] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13144|Lenograstim CSF3R common genes common pathways GO:0007165| signal transduction CSF3R;LYN;MAP2K1;SRC;BCR GO:0007155| cell adhesion ABL1;SRC;HCK;CSF3R GO:0019221| cytokine-mediated signaling pathway CSF3R;HCK 4983:[DB06616 DB08104] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 4984:[DB06616 DB00884] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042493| response to drug LYN;PTGS2;ABCB1;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;HCK GO:0016032| viral reproduction SRC;FDPS;HCK;LYN GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process FDPS;CYP3A4;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0008202| steroid metabolic process CYP2C8;FDPS;CYP3A4 GO:0034605| cellular response to heat PTGS2;LYN GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;ABL1 4985:[DB06616 DB01014] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0007165| signal transduction LYN;PPARG;MAP2K1;SRC;BCR GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0014070| response to organic cyclic compound LYN;PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;LYN;PTGS2;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0042127| regulation of cell proliferation PTGS2;ABL1;PTGS1;SRC GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0006629| lipid metabolic process CYP3A4;PPARG;PTGS2;PTGS1 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0009612| response to mechanical stimulus PPARG;SRC GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2;PPARG GO:0008284| positive regulation of cell proliferation HCK;PTGS2;LYN;CDK2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;PPARG;CDK2;MAP3K2 GO:0042493| response to drug PTGS2;PPARG;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS1;ALOX5;HCK;PTGS2;LYN 4986:[DB06616 DB04334] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;AOC3;CYP3A4 GO:0007155| cell adhesion ABL1;AOC3;HCK;SRC GO:0006954| inflammatory response LYN;AOC3;HCK GO:0055114| oxidation-reduction process CYP2C8;AOC3;CYP3A4 4987:[DB06616 DB14041] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14041|Fremanezumab CALCA;CALCB common genes common pathways GO:0007165| signal transduction LYN;CALCB;MAP2K1;BCR;SRC GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;CALCA;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0045087| innate immune response LYN;CALCA;ABL1;HCK;SRC GO:0043542| endothelial cell migration ABL1;CALCA 4988:[DB06616 DB07061] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07061|1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL NMT2 common genes common pathways 4989:[DB06616 DB05265] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05265|Ecabet NOXO1;ureC common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOXO1 4990:[DB06616 DB05479] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05479|CZEN 002 MC1R common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;MC1R;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MC1R GO:0035556| intracellular signal transduction SRC;BCR;MC1R;CAMK2G;LYN GO:0007275| multicellular organismal development MC1R;CAMK2G;CDK2 4991:[DB06616 DB01677] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01677|Fumaric Acid mdh;ME2;FAH common genes common pathways GO:0055114| oxidation-reduction process ME2;CYP2C8;CYP3A4 4992:[DB06616 DB01056] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0055085| transmembrane transport SCN5A;ABCB1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0002576| platelet degranulation LYN;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;LYN;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 4993:[DB06616 DB04876] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04876|Vildagliptin DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;DPP4;HCK GO:0043542| endothelial cell migration DPP4;ABL1 GO:0031295| T cell costimulation LYN;DPP4;SRC 4994:[DB06616 DB02393] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02393|D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate PFKFB1 common genes common pathways GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CDK2;LYN;PFKFB1;CAMK2G GO:0032868| response to insulin stimulus PFKFB1;LYN 4995:[DB06616 DB08057] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways GO:0030168| platelet activation LCK;SRC;LYN GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;LCK;HCK;MAP2K2;BCR;SRC;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;LCK GO:0031295| T cell costimulation LYN;LCK;SRC GO:0016310| phosphorylation ABL1;LCK;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0030097| hemopoiesis LCK;LYN GO:0006470| protein dephosphorylation LCK;CAMK2G GO:0016477| cell migration LCK;SRC GO:0050690| regulation of defense response to virus by virus HCK;LCK GO:0050853| B cell receptor signaling pathway LYN;LCK;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;BCR;MAP2K2;HCK;LCK;MAP2K1 GO:0042127| regulation of cell proliferation LCK;SRC;ABL1 GO:0045087| innate immune response HCK;LCK;SRC;ABL1;LYN GO:0050900| leukocyte migration LYN;SRC;LCK GO:0042493| response to drug LYN;SRC;ABCB1;LCK GO:0038083| LCK;HCK;SRC;ABL1;LYN GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC GO:0016032| viral reproduction LYN;SRC;LCK;HCK 4996:[DB06616 DB07766] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07766|(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} CAMK2A;CDK16 common genes common pathways GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;CAMK2A;MAP2K2 GO:0000082| G1/S transition of mitotic cell cycle CDK2;CAMK2G;CAMK2A GO:0006816| calcium ion transport CAMK2G;CAMK2A GO:0007399| nervous system development CAMK2A;CAMK2G GO:0035556| intracellular signal transduction CAMK2G;LYN;CAMK2A;SRC;BCR GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC;CAMK2A GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;SRC;CAMK2A;BCR;ABL1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2A;CAMK2G GO:0031175| neuron projection development LYN;CDK16 GO:0006887| exocytosis HCK;CDK16 GO:1900034| CAMK2G;CAMK2A GO:0060333| interferon-gamma-mediated signaling pathway CAMK2A;HCK;CAMK2G GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;CAMK2A;CDK16;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0030154| cell differentiation CAMK2G;HCK;CAMK2A;CDK16 GO:0016310| phosphorylation MAP2K2;BCR;CAMK2A;CDK16;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN 4997:[DB06616 DB11077] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SULT1A1 GO:0006805| xenobiotic metabolic process SULT1A1;CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP4A11 GO:0032496| response to lipopolysaccharide BCR;ADH5 GO:0055114| oxidation-reduction process CYP4A11;CYP3A4;ADH5;CYP2C8 GO:0097267| CYP2C8;CYP4A11 GO:0032869| cellular response to insulin stimulus SRC;ENPP1 GO:0008202| steroid metabolic process CYP2C8;SULT1A1;CYP3A4 4998:[DB06616 DB11093] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0007417| central nervous system development LYN;S100B;SRC GO:0010595| positive regulation of endothelial cell migration SPARC;ABL1;PDCD6;CALR GO:0030335| positive regulation of cell migration CIB1;LYN GO:0043547| positive regulation of GTPase activity RGN;BCR GO:0043434| response to peptide hormone stimulus LYN;SPARC GO:0034605| cellular response to heat LYN;PDCD6 GO:0030154| cell differentiation TPT1;CAMK2G;CALR3;CATSPER1;HCK;CIB1 GO:0007204| elevation of cytosolic calcium ion concentration CIB2;CACNA1C;CACNA1A;SLC8A1;ABL1 GO:0071456| cellular response to hypoxia S100B;SLC8A1;SRC;CASR GO:0006810| transport CACNB4;ABCB1;CACNA1I;CACNB1;CACNA1E;SRI;CACNB3 GO:0006813| potassium ion transport CHP1;CDK2 GO:1900026| CIB1;ABL1;CALR GO:0007165| signal transduction LYN;SRI;CASR;SPARC;S100A6;SRC;CACNA1I;BCR;MAP2K1 GO:0006887| exocytosis CADPS;CADPS2;HCK GO:0051222| positive regulation of protein transport CHP1;SRC GO:0010907| positive regulation of glucose metabolic process SRC;RGN GO:0065009| regulation of molecular function NRXN1;CAMK2G GO:0051281| positive regulation of release of sequestered calcium ion into cytosol SRI;CASQ1;ABL1 GO:0008283| cell proliferation S100B;SRC GO:0038095| LYN;CALM1 GO:0050663| cytokine secretion S100A13;LYN GO:0014070| response to organic cyclic compound LYN;CASR GO:0071901| negative regulation of protein serine/threonine kinase activity CIB1;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;CIB1;MAP2K1;ABL1 GO:0055085| transmembrane transport TRPV6;CACNA1H;CACNA1G;CATSPER1;CACNA1S;TRPV5;CACNA1E;RYR3;CALM1;CACNA1A;CACNA1D;SLC8A1;CACNA1I;ABCB1;CACNA1F;CACNA1C;RYR2;RYR1 GO:0006915| apoptotic process CIB1;PDCD6;ABL1;CASR GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;CIB1;MAP2K1;CALM1;CALM3;CALM2 GO:0010628| positive regulation of gene expression SRC;MAP2K1;CASR;CALR GO:0034614| cellular response to reactive oxygen species SLC8A1;SRC GO:0007411| axon guidance NRXN1;SRC GO:0007049| cell cycle CDK2;CIB1;SRC GO:0010033| response to organic substance CALR;CASQ1;CDK2 GO:0008285| negative regulation of cell proliferation CIB1;MAP2K1;LYN GO:0050766| positive regulation of phagocytosis CALR;BCR GO:0045892| negative regulation of transcription, DNA-dependent SRC;CALR GO:0042127| regulation of cell proliferation SPARC;ABL1;SRC;CIB1 GO:0032496| response to lipopolysaccharide BCR;SPARC GO:0001933| negative regulation of protein phosphorylation LYN;RGN;CIB1;CHP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;S100A13;ABL1 GO:0007275| multicellular organismal development RYR1;RYR2;CATSPER1;CAMK2G;CDK2 GO:0051259| protein oligomerization CHP1;CAMK2G GO:0002576| platelet degranulation ALB;SPARC;CALM1;LYN GO:0043065| positive regulation of apoptotic process SRC;S100B;ABL1 GO:0008284| positive regulation of cell proliferation CALR;CDK2;LYN;S100B;CIB1;HCK;S100A13;CASR GO:0009615| response to virus SRC;TPT1 GO:0042542| response to hydrogen peroxide SRC;SLC8A1 GO:0035556| intracellular signal transduction BCR;CAPS;SRC;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process CIB1;HCK;SRC;ALB;TPT1;RGN GO:0008360| regulation of cell shape HCK;S100B;S100A13 GO:0007507| heart development MAP2K1;CACNA1C;SPARC;SRI GO:0007155| cell adhesion ABL1;HCK;CIB1;SRC;NRXN1 GO:0045087| innate immune response ABL1;SRC;HCK;S100B;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CALR GO:0042981| regulation of apoptotic process TPT1;CALR;MAP3K2;MAP2K1;MAP2K2 GO:0006974| response to DNA damage stimulus LYN;CDK2;CIB1;ABL1 GO:0042493| response to drug SRC;SLC8A1;ABCB1;CALR;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;CALR GO:0050885| neuromuscular process controlling balance ABL1;BCR;NRXN1 GO:0001934| positive regulation of protein phosphorylation CIB1;ABL1;LYN GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis CIB1;ABL1 GO:0051602| response to electrical stimulus S100A13;SRC GO:0006816| calcium ion transport RYR2;RYR1;CACNA1C;CACNA1F;CACNA1D;SLC8A1;CACNA1I;CACNA1A;CACNB4;PKD1L3;CASR;CACNB1;SRI;RYR3;CACNA1E;CACNA1S;CATSPER1;TRPV5;CACNA1G;PKD2L1;CACNA1H;CACNB3;TPT1;CACNB2;CAMK2G;TRPV6 GO:0051301| cell division CIB1;CDK2 GO:0090398| cellular senescence MAP2K1;CALR GO:0031954| positive regulation of protein autophosphorylation SRC;CALM3;CALM1;CALM2 GO:0051924| regulation of calcium ion transport CASR;SLC8A1;CAMK2G;SRI GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CALM1;CAMK2G 4999:[DB06616 DB12110] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12110|m-Chlorophenylpiperazine HTR2C common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2C;ABL1;MAP2K2;SRC;MAP2K1 GO:0007165| signal transduction BCR;SRC;MAP2K1;HTR2C;LYN GO:0042493| response to drug LYN;ABCB1;SRC;HTR2C 5000:[DB06616 DB08358] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAPKAPK3;MAP3K2;ABL1;SRC;BCR;MAP2K2;MAPKAPK2;HCK;MAP2K1 GO:0006468| protein phosphorylation ABL1;HCK;MAPKAPK2;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;MAPKAPK3 GO:1900034| CAMK2G;MAPKAPK2 GO:0007165| signal transduction MAPKAPK3;LYN;SRC;BCR;MAP2K1 GO:0000187| activation of MAPK activity MAP2K2;MAPKAPK2;MAP2K1;MAPKAPK3;MAP3K2 GO:0046777| protein autophosphorylation MAPKAPK3;LYN;CAMK2G;MAPKAPK2;HCK;BCR;SRC;ABL1 GO:0032496| response to lipopolysaccharide MAPKAPK3;MAPKAPK2;BCR GO:0007265| Ras protein signal transduction MAPKAPK3;CDK2;MAPKAPK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway MAPKAPK2;SRC;MAPKAPK3 GO:0018105| peptidyl-serine phosphorylation MAPKAPK2;SRC;MAPKAPK3;CDK2;CAMK2G GO:0006974| response to DNA damage stimulus MAPKAPK2;ABL1;LYN;CDK2 GO:0006954| inflammatory response HCK;MAPKAPK2;LYN GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;MAPKAPK2;MAPKAPK3;CAMK2G 5001:[DB06616 DB01354] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction CHRNA7;CHRNA4;GRIA2;SRC;BCR;MAP2K1;GABRA6;LYN;GABRA5 GO:0007420| brain development GABRA5;BCR GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0006810| transport GABRA3;GABRA5;GABRA4;GABRA6;GRIK2;GABRA1;ABCB1 GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0000187| activation of MAPK activity MAP3K2;CHRNA7;MAP2K1;MAP2K2 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;CHRNA7 GO:0006281| DNA repair CHRNA4;ABL1;CDK2 GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;CDK2;LYN GO:0006816| calcium ion transport CAMK2G;CHRNA4;CHRNA7 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;CHRNA7 5002:[DB06616 DB05225] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05225|AM103 ALOX5AP common genes common pathways 5003:[DB06616 DB11948] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11948|Lapachone RBP3 common genes common pathways GO:0006629| lipid metabolic process RBP3;CYP3A4 5004:[DB06616 DB03672] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03672|9-N-Phenylmethylamino-Tacrine BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0042493| response to drug BCHE;LYN;ABCB1;SRC 5005:[DB06616 DB01255] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0006810| transport ABCB1;SLC15A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction TAAR1;LYN;SRC;BCR;MAP2K1 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC15A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 5006:[DB06616 DB07004] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07004|2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide S100B common genes common pathways GO:0008283| cell proliferation SRC;S100B GO:0007417| central nervous system development LYN;SRC;S100B GO:0071456| cellular response to hypoxia S100B;SRC GO:0008284| positive regulation of cell proliferation S100B;HCK;LYN;CDK2 GO:0043065| positive regulation of apoptotic process S100B;SRC;ABL1 GO:0008360| regulation of cell shape HCK;S100B GO:0045087| innate immune response LYN;SRC;S100B;HCK;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;S100B 5007:[DB06616 DB04327] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0007417| central nervous system development LYN;PTEN;SRC GO:0032869| cellular response to insulin stimulus SRC;PTEN GO:0071456| cellular response to hypoxia SRC;PTEN GO:0014070| response to organic cyclic compound PTEN;LYN GO:0006470| protein dephosphorylation PTEN;CAMK2G GO:0016477| cell migration SRC;PTEN GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;LYN;PTEN GO:0007596| blood coagulation LYN;PROCR GO:0008283| cell proliferation PTEN;SRC GO:0031175| neuron projection development LYN;PTEN GO:0006915| apoptotic process PTEN;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade PTEN;ABL1;MAP2K1;SRC;MAP2K2 GO:0010628| positive regulation of gene expression SRC;MAP2K1;PTEN GO:0051895| negative regulation of focal adhesion assembly PTEN;SRC GO:0030336| negative regulation of cell migration PTEN;BCR GO:0010033| response to organic substance PTEN;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTEN;LYN GO:0048008| platelet-derived growth factor receptor signaling pathway PTEN;SRC;BCR;ABL1 GO:0001933| negative regulation of protein phosphorylation PTEN;LYN GO:0043542| endothelial cell migration ABL1;PTEN GO:0048679| regulation of axon regeneration PTEN;MAP2K1 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTEN GO:0002902| regulation of B cell apoptosis LYN;PTEN GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTEN;HCK GO:0051726| regulation of cell cycle ABL1;SRC;BCR;PTEN GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTEN GO:0006629| lipid metabolic process CYP3A4;PTEN GO:0007399| nervous system development CAMK2G;PTEN GO:0007507| heart development MAP2K1;PTEN GO:0042493| response to drug ABCB1;SRC;PTEN;LYN GO:0050900| leukocyte migration SRC;PROCR;LYN 5008:[DB06616 DB03206] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03206|Duvoglustat MAN1B1;xylA common genes common pathways 5009:[DB06616 DB03389] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03389|alpha-D-Xylopyranose LCT common genes common pathways 5010:[DB06616 DB08048] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08048|4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL ESR1;NCOA2 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA2;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction ESR1;LYN;BCR;SRC;MAP2K1 5011:[DB06616 DB08688] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08688|undecan-2-one ACOT13 common genes common pathways 5012:[DB06616 DB06880] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 5013:[DB06616 DB04263] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04263|Geneticin ODC1 common genes common pathways GO:0009615| response to virus ODC1;SRC GO:0008284| positive regulation of cell proliferation HCK;ODC1;CDK2;LYN 5014:[DB06616 DB08693] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 5015:[DB06616 DB00127] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;CASR GO:0055085| transmembrane transport SLC22A1;SLC22A4;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0006915| apoptotic process CASR;ABL1 GO:0014070| response to organic cyclic compound CASR;LYN GO:0007165| signal transduction LYN;ADRB2;BCR;SRC;ADRB1;MAP2K1;CASR GO:0045453| bone resorption ADRB2;SRC GO:0071456| cellular response to hypoxia CASR;SRC GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0051924| regulation of calcium ion transport CASR;CAMK2G GO:0006816| calcium ion transport CASR;CAMK2G GO:0055114| oxidation-reduction process CYP3A4;XDH;SMOX;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;XDH GO:0008284| positive regulation of cell proliferation CASR;HCK;ODC1;LYN;CDK2 GO:0009615| response to virus ODC1;SRC GO:0042127| regulation of cell proliferation ABL1;SRC;SAT1 GO:0001933| negative regulation of protein phosphorylation XDH;LYN 5016:[DB06616 DB07382] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ERN1;ABL1 GO:0046777| protein autophosphorylation CAMK2G;LYN;ERN1;ABL1;BCR;SRC;HCK GO:0036289| MAP2K2;ERN1 GO:0007257| activation of JUN kinase activity MAP3K2;ERN1 GO:0006915| apoptotic process ERN1;ABL1 GO:0007050| cell cycle arrest ERN1;ABL1;MAP2K1 GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;ERN1;MAP3K2;CAMK2G;LYN;CDK2 GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;ERN1;MAP3K2;CAMK2G;LYN;CDK2 5017:[DB06616 DB01712] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway HCK;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;ABL1 GO:0001933| negative regulation of protein phosphorylation LYN;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;SRC 5018:[DB06616 DB00547] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00547|Desoximetasone NR3C1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0051301| cell division CDK2;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0006915| apoptotic process NR3C1;ABL1 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0007165| signal transduction MAP2K1;BCR;SRC;NR3C1;LYN 5019:[DB06616 DB00868] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00868|Benzonatate SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 5020:[DB06616 DB07795] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07795|Fisetin CDK6 common genes common pathways GO:0007050| cell cycle arrest MAP2K1;ABL1;CDK6 GO:0007165| signal transduction CDK6;LYN;SRC;BCR;MAP2K1 GO:2000773| negative regulation of cellular senescence ABL1;CDK6 GO:0030154| cell differentiation CAMK2G;CDK6;HCK GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CDK6;LYN;CDK2 GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CDK6;CAMK2G GO:0007049| cell cycle SRC;CDK6;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;CDK6 GO:0045646| regulation of erythrocyte differentiation LYN;CDK6 GO:2000145| regulation of cell motility CDK6;ABL1 GO:0009615| response to virus CDK6;SRC GO:0042127| regulation of cell proliferation CDK6;SRC;ABL1 GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;CDK6 GO:0000082| G1/S transition of mitotic cell cycle CAMK2G;CDK6;CDK2 GO:0051301| cell division CDK6;CDK2 5021:[DB06616 DB03096] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03096|N-Aminoethylmorpholine CTSD common genes common pathways GO:0006914| autophagy ABL1;CTSD 5022:[DB06616 DB09103] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09103|Ancestim KIT common genes common pathways GO:0043406| positive regulation of MAP kinase activity KIT;SRC GO:0010628| positive regulation of gene expression MAP2K1;KIT;SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;SRC;BCR;HCK;KIT GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;KIT;MAP3K2 GO:0030097| hemopoiesis KIT;LYN GO:0007165| signal transduction SRC;BCR;KIT;MAP2K1;LYN GO:0006468| protein phosphorylation ABL1;MAP2K1;KIT;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway KIT;HCK;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;KIT;LYN GO:0030335| positive regulation of cell migration KIT;LYN GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;KIT;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;KIT GO:0030218| erythrocyte differentiation KIT;LYN GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1;KIT GO:0019221| cytokine-mediated signaling pathway HCK;KIT GO:0006954| inflammatory response KIT;HCK;LYN GO:0008360| regulation of cell shape KIT;HCK GO:0035556| intracellular signal transduction KIT;SRC;BCR;LYN;CAMK2G GO:0008284| positive regulation of cell proliferation KIT;HCK;LYN;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation LYN;BCR;MAP2K2;SRC;MAP2K1;KIT;HCK;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;KIT GO:0042127| regulation of cell proliferation ABL1;SRC;KIT 5023:[DB06616 DB12731] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12731|Daporinad NAMPT common genes common pathways GO:0008284| positive regulation of cell proliferation NAMPT;HCK;LYN;CDK2 GO:0007165| signal transduction LYN;NAMPT;SRC;BCR;MAP2K1 GO:0014070| response to organic cyclic compound NAMPT;LYN 5024:[DB06616 DB07201] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5025:[DB06616 DB05077] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05077|SLV319 CNR1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;CNR1 GO:0043065| positive regulation of apoptotic process CNR1;ABL1;SRC GO:0032496| response to lipopolysaccharide BCR;CNR1 GO:0010976| positive regulation of neuron projection development CNR1;LYN 5026:[DB06616 DB05446] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05446|LJP 1082 APOH common genes common pathways GO:0002576| platelet degranulation LYN;APOH 5027:[DB06616 DB06963] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0043393| regulation of protein binding PLK1;SRC GO:0043066| negative regulation of apoptotic process PLK1;HCK;SRC GO:0051726| regulation of cell cycle SRC;BCR;PLK1;ABL1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC;PLK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;CDK2 GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;PLK1;MAP3K2 GO:0000278| mitotic cell cycle ABL1;PLK1 GO:0051301| cell division CDK2;PLK1 GO:0010389| regulation of G2/M transition of mitotic cell cycle PLK1;CDK2 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;PLK1;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;PLK1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0031648| protein destabilization SRC;PLK1 GO:1900182| SRC;PLK1 GO:0051439| regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle CDK2;PLK1 GO:0008283| cell proliferation PLK1;SRC GO:0000086| G2/M transition of mitotic cell cycle CDK2;PLK1;ABCB1 GO:0045184| establishment of protein localization PLK1;ABL1 GO:0007049| cell cycle CDK2;SRC;PLK1 5028:[DB06616 DB00893] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0042542| response to hydrogen peroxide HBA1;HBB;SRC GO:0002576| platelet degranulation TF;LYN GO:0055114| oxidation-reduction process CYP2C8;FTH1;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;FTH1;MAP2K1 GO:0007596| blood coagulation LYN;HBB 5029:[DB06616 DB00128] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;GOT1 GO:0002376| immune system process LYN;ADSS;HCK;ADSSL1;SRC GO:0017144| drug metabolic process CYP3A4;CYP2C8;CAD GO:0043200| response to amino acid stimulus ASNS;LYN GO:0009636| response to toxin LYN;ASNS GO:0032868| response to insulin stimulus LYN;CAD GO:0055085| transmembrane transport ABCB1;SLC25A12;SLC16A10;SLC25A13 GO:0018107| peptidyl-threonine phosphorylation CAD;MAP2K1;CAMK2G GO:0046777| protein autophosphorylation CAD;HCK;SRC;BCR;ABL1;LYN;CAMK2G GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ASPH GO:0045931| positive regulation of mitotic cell cycle ASNS;ABL1 GO:0006805| xenobiotic metabolic process ACY1;CYP2C8;CYP3A4;ACY3 GO:0043066| negative regulation of apoptotic process ASNS;HCK;SRC GO:0009612| response to mechanical stimulus SRC;ASNS GO:0007507| heart development CAD;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;ASPH;SRC;MAP3K2;CDK2 GO:0031667| response to nutrient levels SRC;ASNS GO:0055114| oxidation-reduction process CYP2C8;ASPH;CYP3A4 GO:0016032| viral reproduction SRC;HCK;ACY3;LYN GO:0006954| inflammatory response LYN;LYZ;HCK 5030:[DB06616 DB06321] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06321|R-348 JAK3 common genes common pathways GO:0006468| protein phosphorylation JAK3;LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;JAK3;CDK2;LYN;MAP3K2 GO:0065009| regulation of molecular function JAK3;CAMK2G GO:0002376| immune system process LYN;JAK3;SRC;HCK GO:0016477| cell migration SRC;JAK3 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;JAK3 GO:0018108| peptidyl-tyrosine phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;LYN;JAK3 GO:0045087| innate immune response LYN;JAK3;HCK;SRC;ABL1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;JAK3;MAP3K2 GO:0035556| intracellular signal transduction JAK3;LYN;CAMK2G;SRC;BCR GO:0038083| HCK;SRC;ABL1;LYN;JAK3 GO:0000165| MAPKKK cascade CAMK2G;JAK3;MAP2K2;MAP2K1 GO:0030218| erythrocyte differentiation LYN;JAK3 GO:0002250| adaptive immune response LYN;JAK3 GO:0006954| inflammatory response HCK;JAK3;LYN 5031:[DB06616 DB02281] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02281|Formycin MTAP common genes common pathways 5032:[DB06616 DB02598] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0032956| regulation of actin cytoskeleton organization PAM;ABL1 GO:0007417| central nervous system development SRC;PAM;LYN GO:0042493| response to drug SRC;ABCB1;LYN;PAM GO:0055114| oxidation-reduction process CYP2C8;PAM;CYP3A4 GO:0007507| heart development PAM;MAP2K1 5033:[DB06616 DB05209] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05209|SYM001 RHD common genes common pathways 5034:[DB06616 DB04437] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04437|Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline FABP4 common genes common pathways GO:0050727| regulation of inflammatory response LYN;HCK;FABP4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;FABP4 5035:[DB06616 DB14639] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14639|Boldenone undecylenate AR common genes common pathways GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0008284| positive regulation of cell proliferation AR;HCK;LYN;CDK2 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0051259| protein oligomerization AR;CAMK2G GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;SRC;AR GO:0007165| signal transduction AR;MAP2K1;SRC;BCR;LYN GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC 5036:[DB06616 DB06802] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;PTGS2;CDK2;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0042493| response to drug PTGS2;LYN;SRC;ABCB1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 5037:[DB06616 DB00797] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction ADRA2A;MAP2K1;SRC;ADRA1A;BCR;HRH2;LYN;ADRA2B;ADRA2C;HRH1 GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0030168| platelet activation ADRA2B;LYN;ADRA2C;ADRA2A;SRC GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;ADRA1A;SRC;MAP2K1 GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;ADRA2A;HCK GO:0035556| intracellular signal transduction CAMK2G;LYN;ADRA1A;SRC;BCR GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0006954| inflammatory response HRH1;LYN;HCK GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0042493| response to drug SRC;ADRA1A;ABCB1;LYN GO:0043114| regulation of vascular permeability HRH1;BCR;SRC 5038:[DB06616 DB00345] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways GO:0055085| transmembrane transport SLC22A6;SLCO1A2;SLCO3A1;ABCC1;SLC22A4;SLCO1B1;SLC22A8;SLC22A5;ABCB1;SLC22A7;SLC16A1;ABCC2;SLC22A2;SLC22A11 GO:0006855| drug transmembrane transport ABCC1;SLC22A5;ABCB1;SLC22A2;ABCC2 GO:0009636| response to toxin SLC22A8;LYN GO:0006810| transport ABCC1;ABCB1;ABCC2 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0050900| leukocyte migration SRC;SLC16A1;LYN GO:0042493| response to drug ABCC2;ABCB1;SRC;LYN;ABCC1 GO:0032496| response to lipopolysaccharide BCR;ABCC2 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;ABCC2 5039:[DB06616 DB02783] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 5040:[DB06616 DB07628] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07628|6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one PKM common genes common pathways GO:0032869| cellular response to insulin stimulus PKM;SRC GO:0016310| phosphorylation PKM;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2 GO:0010033| response to organic substance CDK2;PKM GO:0032868| response to insulin stimulus PKM;LYN 5041:[DB06616 DB07895] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07895|ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID FNTB;FNTA common genes common pathways GO:0042127| regulation of cell proliferation FNTB;ABL1;SRC GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;SRC 5042:[DB06616 DB06444] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06444|Dexanabinol TNF common genes common pathways GO:0001934| positive regulation of protein phosphorylation LYN;TNF;ABL1 GO:0050900| leukocyte migration SRC;TNF;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;CDK2;TNF GO:0010629| negative regulation of gene expression TNF;MAP2K2;MAP2K1 GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0006954| inflammatory response HCK;LYN;TNF GO:0007275| multicellular organismal development TNF;CDK2;CAMK2G GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC;TNF GO:0001932| regulation of protein phosphorylation MAP2K1;TNF;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;TNF;LYN GO:0009615| response to virus SRC;TNF GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;TNF GO:0043065| positive regulation of apoptotic process SRC;ABL1;TNF GO:0050727| regulation of inflammatory response HCK;TNF;LYN GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TNF;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;TNF GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent TNF;SRC GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0010033| response to organic substance TNF;CDK2 GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0010628| positive regulation of gene expression TNF;SRC;MAP2K1 GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0051222| positive regulation of protein transport SRC;TNF GO:0050715| positive regulation of cytokine secretion TNF;SRC 5043:[DB06616 DB05595] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05595|Farletuzumab FOLR1 common genes common pathways GO:0048678| response to axon injury FOLR1;LYN 5044:[DB06616 DB08174] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08174|5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 5045:[DB06616 DB06103] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06103|VX-148 IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;IMPDH1;IMPDH2 5046:[DB06616 DB00061] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00061|Pegademase bovine GRB2 common genes common pathways GO:0045087| innate immune response ABL1;GRB2;SRC;HCK;LYN GO:0035635| entry of bacterium into host cell SRC;GRB2 GO:0007265| Ras protein signal transduction GRB2;CDK2 GO:0042127| regulation of cell proliferation ABL1;GRB2;SRC GO:0030838| positive regulation of actin filament polymerization HCK;GRB2 GO:0038096| LYN;SRC;HCK;ABL1;GRB2 GO:0038128| GRB2;SRC GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2;GRB2 GO:0051897| positive regulation of protein kinase B signaling cascade GRB2;SRC GO:0042770| signal transduction in response to DNA damage GRB2;ABL1 GO:0016032| viral reproduction SRC;HCK;GRB2;LYN GO:0050900| leukocyte migration LYN;GRB2;SRC GO:0038083| LYN;GRB2;ABL1;HCK;SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;GRB2;ABL1 GO:0065009| regulation of molecular function GRB2;CAMK2G GO:0030154| cell differentiation GRB2;HCK;CAMK2G GO:0031295| T cell costimulation LYN;SRC;GRB2 GO:0007411| axon guidance GRB2;SRC GO:0038095| LYN;GRB2 GO:0016477| cell migration GRB2;SRC 5047:[DB06616 DB07002] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;NOS2 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC 5048:[DB06616 DB01113] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01113|Papaverine PDE4B;PDE10A common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;PDE4B;PDE10A GO:0071222| cellular response to lipopolysaccharide ABL1;PDE4B;SRC;BCR GO:0050900| leukocyte migration LYN;SRC;PDE4B 5049:[DB06616 DB07364] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways GO:0007420| brain development CDK5R1;BCR GO:0006887| exocytosis CDK5;HCK GO:0030900| forebrain development SRC;CDK5 GO:0032956| regulation of actin cytoskeleton organization ABL1;CDK5R1 GO:0006468| protein phosphorylation CDK5;CAMK2G;LYN;CDK2;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;CDK5;MAP3K2 GO:0048013| ephrin receptor signaling pathway SRC;CDK5R1;LYN GO:0007411| axon guidance CDK5R1;SRC GO:0007049| cell cycle SRC;CDK2;CDK5 GO:0045892| negative regulation of transcription, DNA-dependent SRC;CDK5R1;CDK5 GO:0071902| positive regulation of protein serine/threonine kinase activity CDK5R1;MAP2K1;MAP2K2;SRC GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;LYN;CDK5;CAMK2G GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CDK5R1;CDK5;CAMK2G GO:0006915| apoptotic process ABL1;CDK5 GO:0031175| neuron projection development CDK5;CDK5R1;LYN GO:0030182| neuron differentiation CDK5;CDK5R1;MAP2K1;ABL1 GO:0008283| cell proliferation SRC;CDK5;CDK5R1 GO:0016477| cell migration SRC;CDK5 GO:0007399| nervous system development CDK5;CAMK2G GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;CDK5;MAP3K2 GO:1901796| CDK5;CDK2;CDK5R1 GO:0018105| peptidyl-serine phosphorylation CDK5;CAMK2G;CDK2;CDK5R1;SRC GO:0021697| cerebellar cortex formation CDK5;MAP2K1 GO:2000251| positive regulation of actin cytoskeleton reorganization CDK5;ABL1;HCK GO:0051301| cell division CDK5;CDK2 GO:1901216| CDK5;ABL1 5050:[DB06616 DB05758] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05758|CYT007-TNFQb TNF common genes common pathways GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0051222| positive regulation of protein transport SRC;TNF GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;TNF GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0010033| response to organic substance CDK2;TNF GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0010628| positive regulation of gene expression TNF;SRC;MAP2K1 GO:0007275| multicellular organismal development CAMK2G;CDK2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF GO:0001932| regulation of protein phosphorylation TNF;LYN;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;SRC;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;TNF;HCK GO:0071222| cellular response to lipopolysaccharide TNF;ABL1;SRC;BCR GO:0009615| response to virus TNF;SRC GO:0050727| regulation of inflammatory response TNF;LYN;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC;TNF GO:0001934| positive regulation of protein phosphorylation ABL1;TNF;LYN GO:0050900| leukocyte migration SRC;LYN;TNF GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;TNF;CDK2;MAP2K2;SRC;MAP2K1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TNF GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;TNF GO:0006954| inflammatory response HCK;LYN;TNF 5051:[DB06616 DB07081] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0007155| cell adhesion HCK;SRC;ABL1;DPP4 GO:0008284| positive regulation of cell proliferation CDK2;LYN;DPP4;HCK GO:0043542| endothelial cell migration DPP4;ABL1 5052:[DB06616 DB07683] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07683|N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine MMP12 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;MMP12 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;MMP12 5053:[DB06616 DB02681] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02681|2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium CKS1B common genes common pathways GO:0045737| positive regulation of cyclin-dependent protein kinase activity CKS1B;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;SRC;CKS1B GO:0006355| regulation of transcription, DNA-dependent ABL1;CKS1B GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K2;MAP2K1;CKS1B GO:0051301| cell division CDK2;CKS1B GO:0008283| cell proliferation SRC;CKS1B GO:0007049| cell cycle SRC;CKS1B;CDK2 5054:[DB06616 DB00205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00205|Pyrimethamine DHFR;HEXB;CYP2C8;SLC47A1;SLC47A2 common genes CYP2C8 common pathways GO:0006855| drug transmembrane transport SLC47A2;ABCB1;SLC47A1 GO:0055085| transmembrane transport SLC47A2;SLC47A1;ABCB1 GO:0002933| CYP2C8;CYP3A4 GO:0048477| oogenesis SRC;HEXB GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0097267| CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 GO:0050885| neuromuscular process controlling balance BCR;HEXB;ABL1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008360| regulation of cell shape HCK;HEXB GO:0006082| organic acid metabolic process CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8 5055:[DB06616 DB06495] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06495|Onercept TNF common genes common pathways GO:0051222| positive regulation of protein transport TNF;SRC GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0010033| response to organic substance TNF;CDK2 GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0045892| negative regulation of transcription, DNA-dependent TNF;SRC GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0010628| positive regulation of gene expression TNF;MAP2K1;SRC GO:0000187| activation of MAPK activity MAP3K2;TNF;MAP2K1;MAP2K2 GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;MAP2K1;SRC;MAP2K2;ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;TNF;HCK GO:0050727| regulation of inflammatory response HCK;LYN;TNF GO:0043065| positive regulation of apoptotic process TNF;SRC;ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;TNF GO:0009615| response to virus TNF;SRC GO:0007275| multicellular organismal development TNF;CDK2;CAMK2G GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0001932| regulation of protein phosphorylation MAP2K1;LYN;TNF GO:0042127| regulation of cell proliferation ABL1;SRC;TNF GO:0000165| MAPKKK cascade CAMK2G;TNF;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0006954| inflammatory response TNF;LYN;HCK GO:0001934| positive regulation of protein phosphorylation TNF;LYN;ABL1 GO:0050900| leukocyte migration SRC;TNF;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;TNF;MAP3K2 GO:0010629| negative regulation of gene expression TNF;MAP2K1;MAP2K2 5056:[DB06616 DB01897] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 GO:0007165| signal transduction SRC;HPGDS;BCR;MAP2K1;LYN 5057:[DB06616 DB04844] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0009636| response to toxin DRD2;LYN;SLC18A2 GO:0055085| transmembrane transport ABCB1;SLC18A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;DRD2;ABL1 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0009791| post-embryonic development SLC18A2;ABL1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CBR1;CYP3A4 GO:0007165| signal transduction SRC;DRD2;BCR;MAP2K1;LYN GO:0030900| forebrain development DRD2;SRC GO:0042493| response to drug LYN;ABCB1;SRC;DRD2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6;CBR1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0048678| response to axon injury DRD2;LYN GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;DRD2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 5058:[DB06616 DB08067] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways GO:0016477| cell migration SRC;JAK2 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;JAK2 GO:0007596| blood coagulation LYN;JAK2 GO:0006915| apoptotic process ABL1;JAK2 GO:0006928| cellular component movement JAK2;MAP2K1 GO:0046777| protein autophosphorylation ABL1;HCK;SRC;BCR;LYN;CAMK2G;JAK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;JAK2 GO:0030335| positive regulation of cell migration LYN;JAK2 GO:0016310| phosphorylation JAK2;MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0000186| activation of MAPKK activity JAK2;MAP3K2 GO:0007204| elevation of cytosolic calcium ion concentration JAK2;ABL1 GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;JAK2;MAP3K2 GO:0030154| cell differentiation JAK2;CAMK2G;HCK GO:0006979| response to oxidative stress JAK2;ABL1 GO:0060333| interferon-gamma-mediated signaling pathway HCK;JAK2;CAMK2G GO:0022408| negative regulation of cell-cell adhesion ABL1;JAK2 GO:0002376| immune system process SRC;HCK;LYN;JAK2 GO:0007165| signal transduction BCR;SRC;MAP2K1;JAK2;LYN GO:0038083| ABL1;SRC;HCK;LYN;JAK2 GO:0030218| erythrocyte differentiation LYN;JAK2 GO:0002250| adaptive immune response LYN;JAK2 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;JAK2 GO:0019221| cytokine-mediated signaling pathway JAK2;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation JAK2;LYN;SRC;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway JAK2;ABL1;BCR;SRC GO:0032496| response to lipopolysaccharide BCR;JAK2 GO:0042127| regulation of cell proliferation ABL1;SRC;JAK2 GO:0018108| peptidyl-tyrosine phosphorylation LYN;JAK2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein JAK2;LYN GO:0007498| mesoderm development HCK;JAK2 GO:0035556| intracellular signal transduction JAK2;CAMK2G;LYN;BCR;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;JAK2 GO:0050727| regulation of inflammatory response LYN;JAK2;HCK GO:0043065| positive regulation of apoptotic process JAK2;ABL1;SRC GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;JAK2;MAP3K2 GO:0045087| innate immune response HCK;SRC;ABL1;JAK2;LYN GO:0045597| positive regulation of cell differentiation JAK2;MAP2K1 5059:[DB06616 DB11278] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A;ADRA1D GO:0030168| platelet activation ADRA2B;LYN;ADRA2C;SRC;ADRA2A GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction MAP2K1;ADRA1A;SRC;ADRB1;BCR;ADRB3;ADRA2A;ADRA1B;ADRA1D;ADRB2;LYN;ADRA2B;ADRA2C GO:0045453| bone resorption SRC;ADRB2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;ADRA1A;SRC;ABL1 GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0008283| cell proliferation ADRA1D;ADRA1B;SRC GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CAMK2G;CDK2 GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2C;ADRA2B GO:0008284| positive regulation of cell proliferation ADRA1D;CDK2;LYN;HCK;ADRA2A GO:0035556| intracellular signal transduction LYN;CAMK2G;ADRA1B;BCR;ADRA1A;SRC GO:0042493| response to drug LYN;ADRA1A;SRC;ABCB1 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR 5060:[DB06616 DB02342] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0009615| response to virus CYP1A1;SRC GO:0043065| positive regulation of apoptotic process ABL1;CYP1B1;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;HIF1A GO:0060065| uterus development SRC;CYP19A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1B1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8;CYP1A1 GO:0010634| positive regulation of epithelial cell migration SRC;HIF1A GO:0007155| cell adhesion CYP1B1;SRC;HCK;ABL1 GO:0032496| response to lipopolysaccharide COMT;CYP1A1;BCR GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0042127| regulation of cell proliferation HIF1A;SRC;ABL1 GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;HIF1A GO:0042493| response to drug SRC;ABCB1;COMT;CYP1A1;LYN GO:0010629| negative regulation of gene expression MAP2K2;HIF1A;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent HIF1A;MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;CYP1A1;CYP2C8;CYP1B1 GO:0007165| signal transduction SRC;BCR;HIF1A;MAP2K1;LYN GO:0097267| CYP1A1;CYP2C8;CYP1B1 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP1A1;CYP2C8;CYP1B1 GO:0071456| cellular response to hypoxia HIF1A;SRC GO:0030154| cell differentiation HCK;HIF1A;CAMK2G GO:0030336| negative regulation of cell migration CYP1B1;BCR GO:0001922| B-1 B cell homeostasis HIF1A;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;HIF1A;SRC GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0008285| negative regulation of cell proliferation MAP2K1;CYP1B1;LYN GO:0010033| response to organic substance CDK2;CYP1A1 GO:0008283| cell proliferation SRC;CYP1A1 GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;HIF1A GO:0014070| response to organic cyclic compound COMT;LYN;CYP1A1 GO:0009636| response to toxin CYP1B1;CYP1A1;LYN GO:0002933| CYP1A1;CYP3A4;CYP2C8 5061:[DB06616 DB14502] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0055085| transmembrane transport SLC20A1;SLC20A2;ABCB1;SLC34A3;SLC34A2 GO:0007165| signal transduction SLC20A1;LYN;SRC;BCR;MAP2K1 GO:0006810| transport SLC20A1;SLC20A2;ABCB1 GO:0043434| response to peptide hormone stimulus SLC34A1;LYN GO:0016032| viral reproduction SLC20A2;SRC;HCK;LYN GO:0042493| response to drug SRC;ABCB1;SLC34A1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;ABL1 5062:[DB06616 DB02417] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02417|2,4,6-Tribromophenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5063:[DB06616 DB14013] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14013|SR-9009 NR1D1;NR1D2 common genes common pathways GO:0034144| negative regulation of toll-like receptor 4 signaling pathway LYN;NR1D1 GO:0030154| cell differentiation CAMK2G;NR1D1;HCK GO:0045892| negative regulation of transcription, DNA-dependent NR1D1;NR1D2;SRC GO:0050727| regulation of inflammatory response LYN;HCK;NR1D2 GO:0071222| cellular response to lipopolysaccharide NR1D1;ABL1;SRC;BCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1D1;CDK2;NR1D2 GO:0006355| regulation of transcription, DNA-dependent NR1D2;ABL1;NR1D1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;NR1D1;MAP3K2;MAP2K2;SRC;MAP2K1;NR1D2 5064:[DB06616 DB07410] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways 5065:[DB06616 DB03542] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;IMPA1;LYN 5066:[DB06616 DB00507] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00507|Nitazoxanide SLC19A1 common genes common pathways 5067:[DB06616 DB07776] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESRRA;ESRRB;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent ESRRB;ESRRA;SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0043542| endothelial cell migration ABL1;CYP1B1 GO:0042127| regulation of cell proliferation ESRRA;ABL1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;ESRRB;CDK2 GO:0007155| cell adhesion ABL1;HCK;CYP1B1;SRC GO:0043065| positive regulation of apoptotic process SRC;CYP1B1;ABL1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP1B1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1 GO:0008283| cell proliferation SRC;ESRRB GO:0009636| response to toxin CYP1B1;LYN GO:0070301| cellular response to hydrogen peroxide CYP1B1;ABL1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;CYP1B1 GO:0030336| negative regulation of cell migration CYP1B1;BCR GO:0008202| steroid metabolic process CYP3A4;CYP1B1;CYP2C8 GO:0097267| CYP2C8;CYP1B1 5068:[DB06616 DB06689] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways GO:0042493| response to drug LYN;CYP2E1;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0045087| innate immune response LYN;F12;ABL1;SRC;HCK GO:0007596| blood coagulation F12;LYN GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 5069:[DB06616 DB00922] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0006813| potassium ion transport CDK2;KCNJ11;KCNJ8 GO:0007165| signal transduction BCR;SRC;MAP2K1;PDE3A;LYN GO:0055085| transmembrane transport ABCB1;KCNJ11 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PDE3A GO:0043066| negative regulation of apoptotic process SRC;HCK;PDE3A GO:0006629| lipid metabolic process PDE3A;CYP3A4 GO:0007507| heart development MAP2K1;KCNJ8 GO:0032496| response to lipopolysaccharide BCR;KCNJ8 GO:0042493| response to drug PDE3A;LYN;KCNJ11;ABCB1;SRC 5070:[DB06616 DB01176] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0006954| inflammatory response HCK;HRH1;LYN GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0007165| signal transduction HRH1;LYN;MAP2K1;BCR;SRC GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;SULT1E1;CYP2C8 5071:[DB06616 DB09328] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C8 GO:0009725| response to hormone stimulus ACAT1;LYN GO:0007420| brain development BCR;ACAT1 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A2;LYN;ACAT1 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FADS1;CYP1A2;ELOVL4;ACAA1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;FADS1;CYP2E1;CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent FADS1;ABL1 GO:0042493| response to drug SRC;ABCB1;CYP2E1;LYN;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 5072:[DB06616 DB03597] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity PDE5A;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;PDE9A;PDE5A;LYN 5073:[DB06616 DB04857] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04857|Brasofensine DRD2 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;DRD2 GO:0048678| response to axon injury DRD2;LYN GO:0035556| intracellular signal transduction CAMK2G;LYN;DRD2;SRC;BCR GO:0009636| response to toxin DRD2;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;DRD2;MAP2K1 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0007165| signal transduction MAP2K1;BCR;SRC;DRD2;LYN GO:0030900| forebrain development DRD2;SRC 5074:[DB06616 DB02661] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways GO:0016310| phosphorylation PAPSS1;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G 5075:[DB06616 DB08229] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways GO:0001782| B cell homeostasis CASP3;LYN GO:0030218| erythrocyte differentiation LYN;CASP3 GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0042493| response to drug ABCB1;SRC;CASP3;LYN GO:0006974| response to DNA damage stimulus CDK2;LYN;ABL1;CASP3 GO:0007507| heart development CASP3;MAP2K1 GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR;CASP3 GO:0043066| negative regulation of apoptotic process SRC;HCK;CASP3 GO:0043065| positive regulation of apoptotic process ABL1;SRC;CASP3 GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0032496| response to lipopolysaccharide CASP3;BCR GO:0010033| response to organic substance CASP3;CDK2 GO:0006915| apoptotic process ABL1;CASP3 GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0030216| keratinocyte differentiation MAP2K1;CASP3 GO:0030182| neuron differentiation ABL1;CASP3;MAP2K1 GO:0030889| negative regulation of B cell proliferation CASP3;LYN 5076:[DB06616 DB02079] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02079|Aminooxyacetic acid AGXT common genes common pathways 5077:[DB06616 DB05524] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05524|Pelitinib EGFR common genes common pathways GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;MAP2K1;EGFR;HCK;BCR;MAP2K2;SRC GO:0098609| EGFR;SRC GO:0030335| positive regulation of cell migration EGFR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;EGFR GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;EGFR;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:1903800| MAP2K2;EGFR;MAP2K1 GO:0000186| activation of MAPKK activity MAP3K2;EGFR GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:0006979| response to oxidative stress ABL1;EGFR GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;EGFR GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;LYN GO:0008283| cell proliferation SRC;EGFR GO:0014070| response to organic cyclic compound LYN;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;EGFR;MAP2K2;SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;HCK;EGFR;ABL1 GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0042127| regulation of cell proliferation SRC;EGFR;ABL1 GO:0007275| multicellular organismal development CAMK2G;CDK2;EGFR GO:0018108| peptidyl-tyrosine phosphorylation SRC;BCR;MAP2K2;HCK;EGFR;MAP2K1;ABL1;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;EGFR GO:0035556| intracellular signal transduction BCR;SRC;EGFR;CAMK2G;LYN GO:2000145| regulation of cell motility ABL1;EGFR GO:0043066| negative regulation of apoptotic process EGFR;HCK;SRC GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0038083| LYN;EGFR;HCK;SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;EGFR;MAP2K2;SRC;CDK2;MAP3K2 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;EGFR GO:0001934| positive regulation of protein phosphorylation EGFR;ABL1;LYN GO:0038128| SRC;EGFR GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;EGFR;MAP2K2 GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC 5078:[DB06616 DB11155] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0043542| endothelial cell migration ABL1;CYP1B1 GO:0032496| response to lipopolysaccharide BCR;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0007155| cell adhesion HCK;CYP1B1;SRC;ABL1 GO:0009615| response to virus SRC;CYP1A1 GO:0043065| positive regulation of apoptotic process SRC;CYP1B1;ABL1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1;CYP1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP1B1;CYP3A4;CYP1A1 GO:0042493| response to drug ABCB1;SRC;CYP1A1;LYN GO:0008202| steroid metabolic process CYP1B1;CYP2C8;CYP1A1;CYP3A4 GO:0097267| CYP1A1;CYP2C8;CYP1B1 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0008283| cell proliferation SRC;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;LYN GO:0009636| response to toxin LYN;CYP1A1;CYP1B1 GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0008285| negative regulation of cell proliferation CYP1B1;MAP2K1;LYN GO:0010033| response to organic substance CDK2;CYP1A1 GO:0030336| negative regulation of cell migration CYP1B1;BCR GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 5079:[DB06616 DB00348] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00348|Nitisinone HPD common genes common pathways GO:0055114| oxidation-reduction process HPD;CYP3A4;CYP2C8 5080:[DB06616 DB11644] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11644|Tafamidis TTR common genes common pathways GO:0006810| transport ABCB1;TTR 5081:[DB06616 DB03217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03217|DPI59 SRC common genes SRC common pathways GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;LYN GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0086098| SRC GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;BCR GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion ABL1;SRC;HCK GO:0045087| innate immune response ABL1;SRC;HCK;LYN GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;SRC;MAP2K2;MAP2K1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0038083| LYN;SRC;HCK;ABL1 GO:0042493| response to drug SRC;ABCB1;LYN GO:0034332| adherens junction organization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0050900| leukocyte migration LYN;SRC GO:0016032| viral reproduction LYN;SRC;HCK GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038096| SRC;HCK;ABL1;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0060491| regulation of cell projection assembly SRC GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;CDK2;LYN;CAMK2G;MAP3K2 GO:0031295| T cell costimulation LYN;SRC GO:0036120| SRC GO:0007417| central nervous system development SRC;LYN GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0071456| cellular response to hypoxia SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0036035| osteoclast development SRC GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0048477| oogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0002376| immune system process LYN;SRC;HCK GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1 GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0045785| positive regulation of cell adhesion SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation ABL1;HCK;BCR;SRC;LYN;CAMK2G GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC 5082:[DB06616 DB11751] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A6;SLC22A8;ABCB1 GO:0009636| response to toxin SLC22A8;LYN 5083:[DB06616 DB02076] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;PGD;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;SRC 5084:[DB06616 DB01203] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K2;SRC;MAP2K1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0072089| stem cell proliferation ABCB1 GO:0007165| signal transduction BCR;ADRB1;SRC;MAP2K1;LYN;ADRB2 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0045453| bone resorption SRC;ADRB2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0099040| ABCB1 GO:0042493| response to drug SRC;ABCB1;LYN GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 5085:[DB06616 DB08373] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;SCGB1A1 GO:0050727| regulation of inflammatory response HCK;SCGB1A1;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter SCGB1A1;CDK2 GO:0042493| response to drug LYN;SCGB1A1;ABCB1;SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;SCGB1A1 GO:0010033| response to organic substance CDK2;SCGB1A1 5086:[DB06616 DB01048] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0042493| response to drug ABCB1;SRC;UGT1A1;LYN GO:0055114| oxidation-reduction process CYP2C8;ADH6;CYP3A4 GO:0016032| viral reproduction LYN;HLA-B;HCK;SRC GO:0032496| response to lipopolysaccharide UGT1A1;BCR GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045087| innate immune response LYN;HLA-B;ABL1;SRC;HCK GO:0014070| response to organic cyclic compound LYN;UGT1A1 GO:0010033| response to organic substance CDK2;UGT1A1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;ADK;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0060333| interferon-gamma-mediated signaling pathway HCK;CAMK2G;HLA-B GO:0002376| immune system process HLA-B;LYN;HCK;SRC GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2C8 5087:[DB06616 DB01338] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01338|Pipecuronium CHRNA2;CHRM2;CHRM3;BCHE common genes common pathways GO:0007399| nervous system development CHRM3;CAMK2G;CHRM2 GO:0009615| response to virus CHRM2;SRC GO:0042493| response to drug ABCB1;SRC;BCHE;LYN GO:0007165| signal transduction LYN;CHRM2;CHRM3;MAP2K1;CHRNA2;BCR;SRC GO:0008283| cell proliferation SRC;CHRM3 GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0006464| protein modification process CHRM3;ABL1 5088:[DB06616 DB04512] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04512|2-Isobutyl-3-Methoxypyrazine LCN9 common genes common pathways 5089:[DB06616 DB06475] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06475|Ruplizumab CD40LG common genes common pathways GO:0006954| inflammatory response LYN;CD40LG;HCK GO:0043066| negative regulation of apoptotic process HCK;SRC;CD40LG GO:0042100| B cell proliferation ABL1;CD40LG GO:0007257| activation of JUN kinase activity MAP3K2;CD40LG GO:0030168| platelet activation CD40LG;LYN;SRC GO:0031295| T cell costimulation CD40LG;LYN;SRC 5090:[DB06616 DB04659] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04659|(1S,2S,3R,4S,5S)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 5091:[DB06616 DB04912] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04912|Stannsoporfin HMOX1;HMOX2 common genes common pathways GO:0034605| cellular response to heat HMOX1;LYN GO:0071456| cellular response to hypoxia HMOX1;SRC GO:0006979| response to oxidative stress ABL1;HMOX1;HMOX2 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;HMOX1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis HMOX1;ABL1 GO:0006915| apoptotic process ABL1;HMOX1 GO:0008285| negative regulation of cell proliferation HMOX1;LYN;MAP2K1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;HMOX1 GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;HMOX1;LYN GO:0043065| positive regulation of apoptotic process HMOX1;ABL1;SRC GO:0042542| response to hydrogen peroxide HMOX1;SRC GO:0055114| oxidation-reduction process HMOX1;CYP3A4;HMOX2;CYP2C8 5092:[DB06616 DB07189] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07189|(1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid ADAM17 common genes common pathways GO:0048536| spleen development ADAM17;ABL1 GO:0030335| positive regulation of cell migration ADAM17;LYN GO:0007155| cell adhesion ADAM17;SRC;HCK;ABL1 GO:0008284| positive regulation of cell proliferation ADAM17;CDK2;LYN;HCK GO:0051272| positive regulation of cellular component movement LYN;ADAM17 GO:0032496| response to lipopolysaccharide ADAM17;BCR GO:0048870| cell motility ADAM17;MAP2K1 GO:0001934| positive regulation of protein phosphorylation LYN;ADAM17;ABL1 GO:0042493| response to drug SRC;ABCB1;ADAM17;LYN GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;ADAM17 5093:[DB06616 DB11090] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0006813| potassium ion transport CDK2;KCNH2 GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest MUC1;CDK2 GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;MUC1;LYN 5094:[DB06616 DB03642] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03642|Benzofuran-2-Carboxylic Acid {(S)-3-Methyl-1-[3-Oxo-1-(Pyridin-2-Ylsulfonyl)Azepan-4-Ylcarbamoyl]Butyl}Amide CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 5095:[DB06616 DB00670] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00670|Pirenzepine CHRM1 common genes common pathways GO:0007399| nervous system development CAMK2G;CHRM1 GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0008283| cell proliferation CHRM1;SRC GO:0006464| protein modification process CHRM1;ABL1 GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRM1;LYN 5096:[DB06616 DB04878] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04878|Voglibose MGAM common genes common pathways 5097:[DB06616 DB00113] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways GO:0050900| leukocyte migration SRC;CEACAM1;LYN GO:0007155| cell adhesion CEACAM1;ABL1;HCK;SRC GO:0016477| cell migration CEACAM1;SRC GO:0007229| integrin-mediated signaling pathway ABL1;CEACAM1;SRC;HCK GO:0032869| cellular response to insulin stimulus SRC;CEACAM1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;CEACAM1 5098:[DB06616 DB11132] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11132|Silicon dioxide MARCO common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade MARCO;ABL1;MAP2K1;SRC;MAP2K2 GO:0002376| immune system process LYN;SRC;HCK;MARCO GO:0001934| positive regulation of protein phosphorylation ABL1;MARCO;LYN GO:0006897| endocytosis MARCO;ABL1 GO:0045087| innate immune response LYN;MARCO;ABL1;HCK;SRC 5099:[DB06616 DB00311] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways GO:2001225| regulation of chloride transport CA7;ABCB1;CA2 GO:0071498| cellular response to fluid shear stress CA2;SRC GO:0006979| response to oxidative stress CA3;ABL1 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0010033| response to organic substance CDK2;CA2 5100:[DB06616 DB00308] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0023014| signal transduction via phosphorylation event KCNH2;LYN GO:0042493| response to drug ABCB1;SRC;KCNJ11;LYN GO:0051924| regulation of calcium ion transport CACNA2D1;CAMK2G GO:0006816| calcium ion transport CACNA2D1;CAMK2G;CACNB1;CACNG1;CACNA1C GO:0007507| heart development MAP2K1;CACNA1C GO:0055085| transmembrane transport KCNJ11;KCNH7;KCNH2;ABCB1;CACNA1C;KCNH6 GO:0007204| elevation of cytosolic calcium ion concentration CACNA1C;ABL1 GO:0006810| transport CACNG1;CACNB1;ABCB1 GO:0006813| potassium ion transport KCNK1;CDK2;KCNJ11;KCNH2;KCNH7;KCNK6;KCNH6 5101:[DB06616 DB02048] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02048|1,2,4-Triazole-Carboxamidine NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;LYN GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0043542| endothelial cell migration ABL1;NOS3 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN 5102:[DB06616 DB09237] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes CYP3A4 common pathways GO:0006816| calcium ion transport CACNA1C;CAMK2G GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process NOS3;CYP2C8;NOS2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;HCK;LYN GO:0071222| cellular response to lipopolysaccharide NOS2;SRC;BCR;ABL1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0007507| heart development CACNA1C;MAP2K1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042127| regulation of cell proliferation NOS2;SRC;ABL1 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0043542| endothelial cell migration NOS3;ABL1 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;NOS3;MAP2K1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0055085| transmembrane transport CACNA1C;ABCB1 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CACNA1C 5103:[DB06616 DB04368] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04368|Bb-3497 def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;PDF;CDK2;LYN 5104:[DB06616 DB03273] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03273|3'-Oxo-Adenosine AHCY common genes common pathways 5105:[DB06616 DB04214] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways GO:0006470| protein dephosphorylation CAMK2G;DUSP23;ACP1 5106:[DB06616 DB03078] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03078|PASBN SRC common genes SRC common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;CAMK2G;LYN GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1 GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0045453| bone resorption SRC GO:0002376| immune system process SRC;HCK;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0060491| regulation of cell projection assembly SRC GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0071456| cellular response to hypoxia SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0038096| SRC;HCK;ABL1;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0042493| response to drug LYN;ABCB1;SRC GO:0038083| LYN;ABL1;SRC;HCK GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration SRC;LYN GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G GO:0071398| cellular response to fatty acid SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0045087| innate immune response LYN;SRC;HCK;ABL1 GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC 5107:[DB06616 DB05382] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05382|Iodine MT-ND5 common genes common pathways GO:0042542| response to hydrogen peroxide MT-ND5;SRC GO:0055114| oxidation-reduction process MT-ND5;CYP2C8;CYP3A4 5108:[DB06616 DB02490] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways GO:0016310| phosphorylation MAP3K2;CKM;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 5109:[DB06616 DB02106] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent THRB;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;THRB GO:0045892| negative regulation of transcription, DNA-dependent THRB;SRC 5110:[DB06616 DB07702] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07702|17alpha-Estriol NCOA5;ESR2 common genes common pathways GO:0007165| signal transduction ESR2;SRC;BCR;MAP2K1;LYN GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1;NCOA5 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2 5111:[DB06616 DB03539] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03539|2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose CHIT1 common genes common pathways 5112:[DB06616 DB02730] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02730|4-Methylthio-Alpha-D-Mannose AMY2B common genes common pathways 5113:[DB06616 DB00463] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7;ABL1 GO:0042493| response to drug GABRG3;SRC;ABCB1;LYN GO:0006816| calcium ion transport CAMK2G;CHRNA7;CHRNA4 GO:0006281| DNA repair CDK2;CHRNA4;ABL1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;MAP2K2;MAP2K1;MAP3K2 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;CHRNA7 GO:0009636| response to toxin LYN;GABRB1 GO:0009791| post-embryonic development ABL1;GABRG2 GO:0006810| transport GABRB3;ABCB1;GABRA4;GRIK2;GABRA6;GABRB2;GABRD;GABRA1;GABRB1;GABRG2;GABRA5;GABRA3 GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0007165| signal transduction CHRNA7;GABRB3;MAP2K1;BCR;GRIA2;CHRNA4;SRC;GABRP;LYN;GABRA6;GABRD;GABRB1;GABRA5;GABRQ;GABRE GO:0007420| brain development BCR;GABRA5 GO:0006979| response to oxidative stress ABL1;CHRNA4 5114:[DB06616 DB00680] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00680|Moricizine SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 5115:[DB06616 DB08035] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;AR GO:0042327| positive regulation of phosphorylation AR;LYN GO:0051259| protein oligomerization AR;CAMK2G GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;AR;SRC;MAP2K2;MAP2K1 GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;AR GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR 5116:[DB06616 DB03338] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARD;SRC GO:0010033| response to organic substance CDK2;PPARD GO:0010628| positive regulation of gene expression PPARD;MAP2K1;SRC GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;SRC GO:0006915| apoptotic process ABL1;PPARD GO:0008283| cell proliferation SRC;PPARD GO:0071456| cellular response to hypoxia SRC;PPARD GO:0030154| cell differentiation HCK;CAMK2G;PPARD GO:0019221| cytokine-mediated signaling pathway FKBP1A;HCK GO:0050728| negative regulation of inflammatory response PPARD;BCR GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;PPARD;CDK2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARD GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0007507| heart development PPARD;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;CDK2 GO:0043066| negative regulation of apoptotic process SRC;HCK;PPARD GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;PPARD GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PPARD GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;ABL1 GO:0001933| negative regulation of protein phosphorylation LYN;FKBP1A GO:0042127| regulation of cell proliferation PPARD;SRC;ABL1 5117:[DB06616 DB00579] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0042493| response to drug SLC6A3;SLC6A4;SRC;ABCB1;LYN;SLC6A2 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0009791| post-embryonic development SLC18A2;ABL1 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0055085| transmembrane transport SLC6A3;SLC6A4;ABCB1;SLC18A2;SLC6A2 GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0009636| response to toxin LYN;SLC18A2;SLC6A4 GO:0007420| brain development SLC6A4;BCR GO:0006810| transport ABCB1;SLC6A2 5118:[DB06616 DB07354] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;TOP1;MAP3K2;CDK2;LYN;CAMK2G GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;TOP1;SRC GO:0016032| viral reproduction TOP1;LYN;SRC;HCK GO:0006260| DNA replication TOP1;CDK2 GO:0042493| response to drug TOP1;LYN;ABCB1;SRC 5119:[DB06616 DB04895] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04895|Pegaptanib NRP1 common genes common pathways GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;NRP1 GO:0016477| cell migration SRC;NRP1 GO:0051496| positive regulation of stress fiber assembly ABL1;NRP1 GO:0070374| positive regulation of ERK1 and ERK2 cascade NRP1;ABL1;MAP2K1;MAP2K2;SRC GO:0007411| axon guidance NRP1;SRC GO:0014911| positive regulation of smooth muscle cell migration NRP1;SRC GO:0010595| positive regulation of endothelial cell migration ABL1;NRP1 GO:0043547| positive regulation of GTPase activity NRP1;BCR GO:0007229| integrin-mediated signaling pathway NRP1;HCK;SRC;ABL1 GO:0030154| cell differentiation NRP1;CAMK2G;HCK GO:0032489| regulation of Cdc42 protein signal transduction ABL1;NRP1 GO:1900026| ABL1;NRP1 GO:0007165| signal transduction NRP1;LYN;SRC;BCR;MAP2K1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis NRP1;ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization NRP1;HCK;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;NRP1;ABL1;SRC GO:0034446| substrate adhesion-dependent cell spreading NRP1;SRC;ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1;NRP1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1;NRP1 GO:0038189| ABL1;NRP1 GO:0043542| endothelial cell migration NRP1;ABL1 GO:0007275| multicellular organismal development CDK2;NRP1;CAMK2G GO:0042327| positive regulation of phosphorylation LYN;NRP1 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;NRP1 GO:0007399| nervous system development NRP1;CAMK2G GO:0007507| heart development NRP1;MAP2K1 5120:[DB06616 DB14581] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14581|CPI-1205 EZH2 common genes common pathways GO:0043547| positive regulation of GTPase activity EZH2;BCR GO:0045892| negative regulation of transcription, DNA-dependent EZH2;SRC GO:0043406| positive regulation of MAP kinase activity SRC;EZH2 GO:0070301| cellular response to hydrogen peroxide EZH2;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity EZH2;MAP2K1;SRC;MAP2K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter EZH2;CDK2 GO:0001932| regulation of protein phosphorylation LYN;EZH2;MAP2K1 GO:0042127| regulation of cell proliferation EZH2;ABL1;SRC GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;EZH2 GO:0006355| regulation of transcription, DNA-dependent EZH2;ABL1 5121:[DB06616 DB14499] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14499|Potassium sulfate ATP1A1 common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;ATP1A1 GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 GO:0006813| potassium ion transport CDK2;ATP1A1 5122:[DB06616 DB04661] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways GO:0016032| viral reproduction LYN;CD1D;SRC;HCK GO:0045087| innate immune response HCK;SRC;CD1D;ABL1;LYN GO:0002376| immune system process LYN;CD1D;SRC;HCK 5123:[DB06616 DB02343] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0007399| nervous system development ACHE;CAMK2G GO:0006260| DNA replication ACHE;CDK2 5124:[DB06616 DB06990] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06990|4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID UNG common genes common pathways GO:0016032| viral reproduction HCK;SRC;LYN;UNG GO:0006281| DNA repair CDK2;UNG;ABL1 GO:0006974| response to DNA damage stimulus ABL1;UNG;LYN;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;UNG 5125:[DB06616 DB08819] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;PTGFR GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance CDK2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0007165| signal transduction BCR;PTGFR;SRC;MAP2K1;LYN GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006954| inflammatory response HCK;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGFR;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK;PTGFR GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0042127| regulation of cell proliferation SRC;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;PTGFR;BCR 5126:[DB06616 DB00627] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0050900| leukocyte migration SLC16A3;LYN;SRC;SLC16A1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042493| response to drug ABCB1;SRC;NNMT;LYN GO:0006629| lipid metabolic process CYP3A4;SLC16A1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0051259| protein oligomerization QPRT;CAMK2G GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0055085| transmembrane transport SLC22A5;SLC16A3;SLC5A8;ABCB1;SLCO2B1;SLC16A1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0006915| apoptotic process ABL1;SLC5A8;HCAR2 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction HCAR3;HCAR2;MAP2K1;SRC;BCR;LYN GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 5127:[DB06616 DB00050] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;GNRHR GO:0001545| primary ovarian follicle growth SRC;LHCGR GO:0007165| signal transduction LYN;LHCGR;GNRHR;MAP2K1;SRC;BCR 5128:[DB06616 DB06732] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes common pathways GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0007049| cell cycle AHR;CDK2;SRC GO:0008285| negative regulation of cell proliferation LYN;CYP1B1;MAP2K1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent AHR;SRC GO:0030336| negative regulation of cell migration CYP1B1;BCR GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0006915| apoptotic process ABL1;AHR GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009636| response to toxin LYN;AHR;CYP1B1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ESR1;NR2F1 GO:0097267| CYP2C8;CYP1B1;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP1B1;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP1B1;CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;SRC;LYN;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESRRA;ABL1;NR2F1;AHR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;AHR;CDK2;ESR1;MAP2K1;SRC;MAP2K2;ESRRA GO:0007155| cell adhesion HCK;CYP1B1;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;CDK2;ESR1;NR2F1 GO:0007399| nervous system development CAMK2G;NR2F1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;ESR1;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0043065| positive regulation of apoptotic process SRC;CYP1B1;ABL1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C8;AHR;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1;CYP1A2 GO:0060065| uterus development SRC;ESR1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042127| regulation of cell proliferation ABL1;ESRRA;SRC GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 5129:[DB06616 DB00341] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00341|Cetirizine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;LYN;MAP2K1;BCR;SRC GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0006954| inflammatory response HCK;LYN;HRH1 5130:[DB06616 DB05983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0006915| apoptotic process NFKBIA;ABL1 GO:0038095| LYN;NFKBIA GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC;NFKBIA GO:0032496| response to lipopolysaccharide BCR;NFKBIA GO:0042127| regulation of cell proliferation NFKBIA;ABL1;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway NFKBIA;HCK;LYN GO:0043066| negative regulation of apoptotic process NFKBIA;SRC;HCK GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;NFKBIA;MAP3K2;CDK2 GO:0016032| viral reproduction NFKBIA;SRC;HCK;LYN 5131:[DB06616 DB09336] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;EPCAM GO:0050900| leukocyte migration LYN;EPCAM;SRC GO:0098609| EPCAM;SRC GO:0042100| B cell proliferation MS4A1;ABL1 5132:[DB06616 DB09532] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09532|Secretin human SCTR common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;SCTR;LYN 5133:[DB06616 DB04100] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0006979| response to oxidative stress ABCC2;ABL1 GO:0006810| transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0071222| cellular response to lipopolysaccharide ABL1;ABCC2;SRC;BCR GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:0042493| response to drug SRC;ABCB1;ABCC2;LYN 5134:[DB06616 DB03041] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 5135:[DB06616 DB03556] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03556|2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 CBR1;CBR1 common genes common pathways GO:0017144| drug metabolic process CBR1;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CBR1;CYP2C8 5136:[DB06616 DB04151] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04151|4-Methyl-Histidine ACTA1 common genes common pathways GO:0009612| response to mechanical stimulus SRC;ACTA1 GO:0010628| positive regulation of gene expression MAP2K1;ACTA1;SRC 5137:[DB06616 DB00126] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0060425| lung morphogenesis MAP2K1;PLOD3 GO:0055114| oxidation-reduction process EGLN2;OGFOD1;P3H1;P4HA1;EGLN3;ALKBH2;CYP2C8;PLOD3;EGLN1;BBOX1;DBH;P3H2;PLOD1;PAM;KDM5D;P4HTM;PHYH;CYP3A4;TMLHE;OGFOD2;PLOD2;ALKBH3;P3H3 GO:0050900| leukocyte migration LYN;DBH;SRC GO:0042493| response to drug SRC;ABCB1;LYN;PAM GO:0006355| regulation of transcription, DNA-dependent KDM5D;ABL1 GO:0006281| DNA repair ALKBH2;ABL1;CDK2;ALKBH3 GO:0006974| response to DNA damage stimulus CDK2;LYN;ALKBH3;ABL1;EGLN3;ALKBH2 GO:0007507| heart development PAM;MAP2K1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;EGLN2 GO:0042127| regulation of cell proliferation SRC;DBH;ABL1;EGLN3 GO:0008285| negative regulation of cell proliferation MAP2K1;P3H1;LYN;P3H3;P3H2 GO:0006464| protein modification process ABL1;PLOD1;PLOD2 GO:0006915| apoptotic process EGLN3;ABL1 GO:0055085| transmembrane transport ABCB1;SLC23A1 GO:0009636| response to toxin LYN;SLC23A1 GO:0060711| labyrinthine layer development EGLN1;MAP2K1 GO:0008283| cell proliferation ALKBH3;SRC;OGFOD1 GO:0045646| regulation of erythrocyte differentiation LYN;P4HTM GO:0007420| brain development SLC23A1;BCR GO:0032956| regulation of actin cytoskeleton organization ABL1;PAM GO:0070989| oxidative demethylation CYP3A4;CYP2C8;ALKBH2 GO:0007417| central nervous system development PAM;LYN;SRC 5138:[DB06616 DB01274] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2A6;CYP2D6;CYP2C19;CYP2C8 GO:0097267| CYP2C9;CYP2C19;CYP2C8 GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;ADRB2 GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2A6;CYP2C9;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2A6;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2C9;CYP2D6;CYP2C8;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2A6;CYP2C9;CYP3A4;CYP2C19;CYP2C8 5139:[DB06616 DB03442] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways 5140:[DB06616 DB09413] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09413|Monopotassium phosphate ALPI common genes common pathways 5141:[DB06616 DB06360] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06360|Lucatumumab CD40 common genes common pathways GO:0042100| B cell proliferation ABL1;CD40 GO:0043406| positive regulation of MAP kinase activity SRC;CD40 GO:0043547| positive regulation of GTPase activity CD40;BCR GO:0030168| platelet activation SRC;CD40;LYN GO:0002376| immune system process SRC;HCK;LYN;CD40 GO:0031667| response to nutrient levels CD40;SRC GO:0001934| positive regulation of protein phosphorylation LYN;CD40;ABL1 GO:0002768| immune response-regulating cell surface receptor signaling pathway CD40;LYN GO:0006954| inflammatory response LYN;CD40;HCK GO:0042127| regulation of cell proliferation CD40;ABL1;SRC GO:0032496| response to lipopolysaccharide BCR;CD40 GO:0007275| multicellular organismal development CAMK2G;CDK2;CD40 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein CD40;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CD40 GO:0071222| cellular response to lipopolysaccharide CD40;ABL1;BCR;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;CD40 5142:[DB06616 DB07122] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07122|1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine PLAU common genes common pathways GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC GO:0006935| chemotaxis PLAU;MAP2K1 GO:0007596| blood coagulation LYN;PLAU GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0030335| positive regulation of cell migration LYN;PLAU GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;PLAU 5143:[DB06616 DB03581] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03581|Glucose-6-Phosphate glmS;GPI;SLCO2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPI GO:0055085| transmembrane transport SLCO2A1;ABCB1 5144:[DB06616 DB00035] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0008284| positive regulation of cell proliferation HCK;AVPR2;LYN;CDK2;AVPR1A;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1;ABL1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;HCK;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0007165| signal transduction SRC;BCR;AVPR2;MAP2K1;AVPR1A;LYN;AVPR1B GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress ABL1;PTGS1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AVPR1B;AVPR1A GO:0034605| cellular response to heat PTGS2;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance PTGS2;AVPR1A;CDK2 GO:0010628| positive regulation of gene expression MAP2K1;AVPR2;SRC GO:0014070| response to organic cyclic compound LYN;PTGS2 5145:[DB06616 DB02745] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways GO:0071456| cellular response to hypoxia SRC;SLC29A1 5146:[DB06616 DB04059] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04059|8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0030335| positive regulation of cell migration LYN;PLAU GO:0007165| signal transduction PLAU;BCR;SRC;MAP2K1;LYN GO:0007596| blood coagulation LYN;PLAU GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0042127| regulation of cell proliferation PLAU;ABL1;SRC GO:0006935| chemotaxis PLAU;MAP2K1 5147:[DB06616 DB11660] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11660|Latanoprostene Bunod PTGFR;SLCO2B1 common genes common pathways GO:0007165| signal transduction PTGFR;SRC;BCR;MAP2K1;LYN GO:0055085| transmembrane transport ABCB1;SLCO2B1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;PTGFR GO:0032496| response to lipopolysaccharide BCR;PTGFR GO:0008284| positive regulation of cell proliferation PTGFR;HCK;LYN;CDK2 GO:0043066| negative regulation of apoptotic process PTGFR;SRC;HCK 5148:[DB06616 DB00669] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes ABCB1 common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR1A GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:1901529| ABCB1 GO:0042493| response to drug SRC;HTR1B;ABCB1;ABCG2;LYN GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0007165| signal transduction HTR1B;SRC;BCR;MAP2K1;HTR1F;HTR1D;HTR1A;LYN GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0009636| response to toxin LYN;HTR1D GO:0008283| cell proliferation HTR1A;SRC GO:0055085| transmembrane transport SLCO1B1;SLCO1A2;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 5149:[DB06616 DB09217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09217|Firocoxib PTGS2 common genes common pathways GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response HCK;LYN;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation SRC;ABL1;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;ABL1 5150:[DB06616 DB00430] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation ALB;LYN 5151:[DB06616 DB05017] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05017|YSIL6 TNF;IL6 common genes common pathways GO:0006954| inflammatory response TNF;LYN;HCK;IL6 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;TNF GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0071803| positive regulation of podosome assembly SRC;TNF GO:0019221| cytokine-mediated signaling pathway HCK;IL6 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;IL6;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;IL6;TNF;CDK2;MAP3K2 GO:0010629| negative regulation of gene expression TNF;MAP2K2;MAP2K1 GO:0001934| positive regulation of protein phosphorylation TNF;LYN;ABL1 GO:0050900| leukocyte migration SRC;LYN;TNF GO:0043066| negative regulation of apoptotic process SRC;HCK;IL6 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;LYN;HCK GO:0050727| regulation of inflammatory response TNF;LYN;HCK GO:0043065| positive regulation of apoptotic process TNF;IL6;SRC;ABL1 GO:0009615| response to virus SRC;TNF GO:0071222| cellular response to lipopolysaccharide TNF;SRC;BCR;IL6;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;IL6;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;TNF GO:0007275| multicellular organismal development CDK2;TNF;CAMK2G GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL6 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0010628| positive regulation of gene expression TNF;SRC;MAP2K1;IL6 GO:0008285| negative regulation of cell proliferation LYN;IL6;MAP2K1 GO:0010033| response to organic substance TNF;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0070301| cellular response to hydrogen peroxide IL6;ABL1 GO:0031175| neuron projection development LYN;IL6 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TNF;MAP3K2 GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;TNF GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0051222| positive regulation of protein transport TNF;SRC GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0030168| platelet activation IL6;SRC;LYN 5152:[DB06616 DB03506] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03506|9-Deazaadenine APRT common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;APRT 5153:[DB06616 DB03455] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways GO:0002376| immune system process LYN;IL2;SRC;HCK GO:0065009| regulation of molecular function IL2;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;IL2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;IL2 GO:0043066| negative regulation of apoptotic process IL2;HCK;SRC GO:0007155| cell adhesion IL2;ABL1;HCK;SRC GO:0001933| negative regulation of protein phosphorylation IL2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL2 GO:0050728| negative regulation of inflammatory response BCR;IL2 GO:0000165| MAPKKK cascade CAMK2G;IL2;MAP2K1;MAP2K2 GO:0002250| adaptive immune response IL2;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;IL2;LYN 5154:[DB06616 DB12119] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12119|Gevokizumab IL1B common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;ABL1 GO:0032496| response to lipopolysaccharide IL1B;BCR GO:0071260| cellular response to mechanical stimulus IL1B;MAP3K2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;IL1B GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;IL1B GO:0050900| leukocyte migration LYN;IL1B;SRC GO:0001934| positive regulation of protein phosphorylation LYN;IL1B;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;SRC;IL1B GO:0019221| cytokine-mediated signaling pathway IL1B;HCK GO:0009743| response to carbohydrate stimulus IL1B;LYN GO:0000165| MAPKKK cascade CAMK2G;IL1B;MAP2K1;MAP2K2 GO:0006954| inflammatory response HCK;IL1B;LYN GO:0030335| positive regulation of cell migration LYN;IL1B GO:0007165| signal transduction IL1B;BCR;SRC;MAP2K1;LYN GO:0070372| regulation of ERK1 and ERK2 cascade LYN;IL1B GO:0006915| apoptotic process IL1B;ABL1 GO:0000187| activation of MAPK activity MAP3K2;IL1B;MAP2K1;MAP2K2 GO:0043407| negative regulation of MAP kinase activity LYN;IL1B GO:0050766| positive regulation of phagocytosis BCR;IL1B GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;IL1B GO:0010628| positive regulation of gene expression IL1B;SRC;MAP2K1 5155:[DB06616 DB07617] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2A6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP2C8 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2C8 5156:[DB06616 DB13751] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13751|Glycyrrhizic acid HSD11B1;TNF;CASP3;NFKB2;NFKB1;LPL;AKR1C4;AKR1C3;AKR1C2;ALB;ABCB11 common genes common pathways GO:0006915| apoptotic process CASP3;NFKB1;ABL1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;TNF GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;TNF GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0038095| LYN;NFKB1 GO:0030182| neuron differentiation ABL1;CASP3;MAP2K1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0030216| keratinocyte differentiation AKR1C3;CASP3;MAP2K1 GO:0010033| response to organic substance CASP3;TNF;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;NFKB1 GO:0045892| negative regulation of transcription, DNA-dependent TNF;NFKB1;SRC GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0010628| positive regulation of gene expression TNF;MAP2K1;SRC GO:0034614| cellular response to reactive oxygen species SRC;AKR1C3 GO:0006810| transport ABCB1;ABCB11 GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0008202| steroid metabolic process HSD11B1;AKR1C2;CYP2C8;CYP3A4;AKR1C4;AKR1C3 GO:0007165| signal transduction NFKB2;LYN;MAP2K1;SRC;BCR;NFKB1 GO:0051222| positive regulation of protein transport SRC;TNF GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0048536| spleen development NFKB2;ABL1 GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0055114| oxidation-reduction process AKR1C2;HSD11B1;CYP2C8;CYP3A4;AKR1C4;AKR1C3 GO:0001934| positive regulation of protein phosphorylation ABL1;TNF;LYN GO:0008209| androgen metabolic process AKR1C4;CYP3A4 GO:0050900| leukocyte migration TNF;LYN;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;TNF;CDK2;MAP2K2;SRC;MAP2K1;NFKB1 GO:0010629| negative regulation of gene expression TNF;NFKB1;MAP2K1;MAP2K2 GO:0042493| response to drug ABCB1;SRC;CASP3;LPL;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;NFKB1;NFKB2 GO:0001782| B cell homeostasis LYN;CASP3 GO:0000165| MAPKKK cascade TNF;CAMK2G;MAP2K1;MAP2K2 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;TNF;SRC;AKR1C2 GO:0071803| positive regulation of podosome assembly SRC;TNF GO:0030218| erythrocyte differentiation CASP3;LYN GO:0006954| inflammatory response NFKB1;HCK;NFKB2;TNF;LYN GO:0050728| negative regulation of inflammatory response BCR;NFKB1 GO:0007275| multicellular organismal development TNF;CDK2;CAMK2G GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC;NFKB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF GO:0001932| regulation of protein phosphorylation TNF;LYN;MAP2K1 GO:0042127| regulation of cell proliferation TNF;SRC;ABL1 GO:0032496| response to lipopolysaccharide BCR;CASP3;NFKB2 GO:0006629| lipid metabolic process CYP3A4;AKR1C2;HSD11B1;LPL GO:0006974| response to DNA damage stimulus ABL1;CASP3;LYN;CDK2 GO:0071260| cellular response to mechanical stimulus MAP3K2;NFKB1 GO:0045087| innate immune response LYN;NFKB2;NFKB1;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2;NFKB2;NFKB1 GO:0007507| heart development CASP3;MAP2K1 GO:0035556| intracellular signal transduction LYN;CAMK2G;CASP3;BCR;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;TNF;LYN GO:0043066| negative regulation of apoptotic process CASP3;HCK;SRC;NFKB1;ALB GO:0050727| regulation of inflammatory response HCK;TNF;LYN GO:0043065| positive regulation of apoptotic process TNF;CASP3;SRC;ABL1 GO:0002576| platelet degranulation LYN;ALB GO:0009615| response to virus SRC;TNF GO:0042542| response to hydrogen peroxide SRC;CASP3 GO:0071222| cellular response to lipopolysaccharide TNF;NFKB1;ABL1;SRC;BCR GO:0008284| positive regulation of cell proliferation HCK;AKR1C2;AKR1C3;CDK2;LYN 5157:[DB06616 DB03711] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03711|6-Hydroxy-6-Methyl-Heptan-3-One LCN9 common genes common pathways 5158:[DB06616 DB02587] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0035556| intracellular signal transduction SRC;ADCY2;BCR;ADCY5;LYN;CAMK2G GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0050885| neuromuscular process controlling balance ADCY5;ABL1;BCR GO:0042493| response to drug GNAS;SRC;ABCB1;LYN GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ADCY5;ABL1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0007165| signal transduction LYN;ADCY2;SRC;BCR;GNAS;MAP2K1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport ABCB1;CFTR GO:0009791| post-embryonic development ABL1;GNAS 5159:[DB06616 DB08049] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0014070| response to organic cyclic compound LYN;COMT GO:0032496| response to lipopolysaccharide COMT;BCR GO:0042493| response to drug COMT;LYN;SRC;ABCB1 5160:[DB06616 DB03040] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03040|Nitrilotriacetic Acid LTF common genes common pathways GO:0001817| regulation of cytokine production LTF;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;LTF GO:0043066| negative regulation of apoptotic process HCK;SRC;LTF GO:0045087| innate immune response ABL1;LTF;SRC;HCK;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;LTF GO:0033690| positive regulation of osteoblast proliferation ABL1;LTF GO:0002376| immune system process LYN;LTF;SRC;HCK 5161:[DB06616 DB01330] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01330|Cefotetan ALB common genes common pathways GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 5162:[DB06616 DB06549] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06549|Labradimil BDKRB2 common genes common pathways GO:0043114| regulation of vascular permeability SRC;BCR;BDKRB2 GO:0006954| inflammatory response HCK;BDKRB2;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;BDKRB2;LYN GO:0007204| elevation of cytosolic calcium ion concentration BDKRB2;ABL1 GO:0007165| signal transduction MAP2K1;SRC;BCR;BDKRB2;LYN 5163:[DB06616 DB01043] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0009636| response to toxin DRD2;LYN GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1;CHRNA7 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;DRD2;CHRNA7;ABL1 GO:0055085| transmembrane transport ABCB1;SLC22A2 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0048013| ephrin receptor signaling pathway SRC;LYN;GRIN2B;GRIN1 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2B6;CYP2C8;CYP2C19 GO:0006810| transport GRIN2B;GRIN2A;ABCB1 GO:0030900| forebrain development DRD2;SRC GO:0065009| regulation of molecular function CAMK2G;GRIN2B;GRIN1;GRIN2A GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4;CYP2B6;CYP2A6 GO:0097267| CYP2C8;CYP2C19 GO:0007165| signal transduction CHRNA7;BCR;SRC;DRD2;MAP2K1;HTR3A;LYN GO:1901216| GRIN2B;ABL1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP2A6;CYP2B6;CYP3A4 GO:0042493| response to drug DRD2;SRC;ABCB1;GRIN2A;LYN GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;CHRNA7 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;CYP2A6;CYP2C8;CYP2C19 GO:0006816| calcium ion transport CHRNA7;GRIN2A;GRIN1;CAMK2G;GRIN3A GO:0000165| MAPKKK cascade GRIN1;CAMK2G;GRIN2B;MAP2K2;MAP2K1;GRIN2A GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0048678| response to axon injury DRD2;LYN GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2B6;CYP2A6 GO:0035556| intracellular signal transduction BCR;SRC;DRD2;CAMK2G;LYN GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2B6;CYP3A4 GO:0043065| positive regulation of apoptotic process GRIN1;ABL1;GRIN2A;SRC GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;LYN;CDK2 5164:[DB06616 DB09472] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09472|Sodium sulfate CA2;CA1 common genes common pathways GO:0010033| response to organic substance CDK2;CA2 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0071498| cellular response to fluid shear stress SRC;CA2 5165:[DB06616 DB09194] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ABL1;ADRA1B;ADRA1D;HTR2A GO:0006810| transport SLC6A2;ABCB1 GO:0030168| platelet activation LYN;ADRA2B;ADRA2C;SRC;ADRA2A GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction HTR2C;ADRA1B;ADRA2A;BCR;DRD2;SRC;ADRA1A;MAP2K1;CHRM4;ADRA2C;CHRM1;HTR2A;LYN;ADRA2B;CHRM2;CHRM5;ADRA1D;CHRM3 GO:0007420| brain development SLC6A4;BCR GO:0030900| forebrain development SRC;DRD2 GO:0055085| transmembrane transport SLC6A2;SLC6A3;SLC6A4;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;HTR2C;ADRA1A;SRC;DRD2;MAP2K2;MAP2K1;HTR2A GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;ADRA2B GO:0008283| cell proliferation ADRA1B;SRC;CHRM4;CHRM1;ADRA1D;CHRM5;CHRM3 GO:0009636| response to toxin DRD2;SLC6A4;LYN GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A;SRC GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0010033| response to organic substance CDK2;SLC6A4 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;ADRA1A;LYN GO:0030336| negative regulation of cell migration DRD2;BCR GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0048678| response to axon injury DRD2;LYN GO:0007275| multicellular organismal development CDK2;CAMK2G;ADRA1D;ADRA1B GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1;CHRM2 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;ADRA2A;SRC GO:0009615| response to virus SRC;CHRM2 GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;ADRA1D;CHRM1;HTR2A;LYN;CDK2 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;ADRA1A;SRC;DRD2;ADRA1B GO:0042493| response to drug ABCB1;DRD2;SRC;ADRA1A;HTR2C;SLC6A4;SLC6A3;SLC6A2;HTR2A;LYN GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK 5166:[DB06616 DB00968] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;ADRA2A GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0030168| platelet activation LYN;SRC;ADRA2A GO:0006810| transport SLC15A1;ABCB1 GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0009636| response to toxin LYN;DDC GO:0014070| response to organic cyclic compound COMT;LYN GO:0055085| transmembrane transport SLC15A1;ABCB1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;ADRA2A;HCK GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0032496| response to lipopolysaccharide BCR;COMT GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0042493| response to drug COMT;LYN;ABCB1;SRC 5167:[DB06616 DB02405] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways GO:0006915| apoptotic process PAEP;ABL1 GO:0007275| multicellular organismal development CDK2;PAEP;CAMK2G 5168:[DB06616 DB07901] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07901|5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE METAP1 common genes common pathways 5169:[DB06616 DB01620] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01620|Pheniramine HRH1;NR1I3 common genes common pathways GO:0007165| signal transduction HRH1;NR1I3;LYN;SRC;BCR;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;SRC GO:0006355| regulation of transcription, DNA-dependent NR1I3;ABL1 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0006954| inflammatory response LYN;HRH1;HCK 5170:[DB06616 DB08952] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08952|Indenolol CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 5171:[DB06616 DB03637] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03637|Guanidine-3-Propanol PRSS3 common genes common pathways GO:0043542| endothelial cell migration ABL1;PRSS3 5172:[DB06616 DB09035] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09035|Nivolumab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PDCD1;SRC;HCK GO:0043065| positive regulation of apoptotic process PDCD1;SRC;ABL1 GO:0007275| multicellular organismal development PDCD1;CDK2;CAMK2G GO:0006915| apoptotic process ABL1;PDCD1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PDCD1 GO:0002376| immune system process SRC;HCK;PDCD1;LYN GO:0031295| T cell costimulation SRC;PDCD1;LYN 5173:[DB06616 DB03028] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03028|1h-Benoximidazole-2-Carboxylic Acid CTSD common genes common pathways GO:0006914| autophagy CTSD;ABL1 5174:[DB06616 DB12159] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12159|Dupilumab IL4R common genes common pathways GO:0007165| signal transduction LYN;IL4R;MAP2K1;SRC;BCR GO:0002376| immune system process SRC;HCK;IL4R;LYN GO:0019221| cytokine-mediated signaling pathway HCK;IL4R GO:0042127| regulation of cell proliferation SRC;ABL1;IL4R 5175:[DB06616 DB08770] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways GO:0006909| phagocytosis HCK;ABL1;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ABL1;ADORA2A GO:0042493| response to drug SRC;ABCB1;LYN;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;SRC GO:0050728| negative regulation of inflammatory response BCR;ADORA2A GO:0006954| inflammatory response LYN;ADORA2A;HCK GO:0051924| regulation of calcium ion transport CAMK2G;ADORA2A GO:0007417| central nervous system development SRC;ADORA2A;LYN GO:0007165| signal transduction SRC;BCR;MAP2K1;ADORA2A;LYN GO:0007596| blood coagulation ADORA2A;LYN GO:0006915| apoptotic process ADORA2A;ABL1 GO:0008285| negative regulation of cell proliferation LYN;ADORA2A;MAP2K1 5176:[DB06616 DB01107] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0009791| post-embryonic development ABL1;GABRG2 GO:0009636| response to toxin GABRB1;LYN GO:0007165| signal transduction BCR;SRC;MAP2K1;GABRB3;GABRE;GABRA5;GABRB1;GABRQ;GABRA6;GABRD;LYN;GABRP GO:0007420| brain development BCR;GABRA5 GO:0006810| transport ABCB1;GABRB3;GABRA3;GABRB1;GABRG2;GABRA5;GABRD;GABRB2;GABRA4;GABRA6;GABRA1 GO:0007417| central nervous system development SRC;GABRA4;LYN GO:0042493| response to drug SRC;ABCB1;GABRG3;LYN 5177:[DB06616 DB02900] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;IGF2R GO:0043065| positive regulation of apoptotic process IGF2R;SRC;ABL1 GO:0009791| post-embryonic development ABL1;IGF2R GO:0007165| signal transduction M6PR;LYN;IGF2R;MAP2K1;BCR;SRC 5178:[DB06616 DB07498] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07498|4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;AKR1B1 GO:0043066| negative regulation of apoptotic process SRC;HCK;AKR1B1 GO:0010033| response to organic substance CDK2;AKR1B1 5179:[DB06616 DB00424] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CHRM1;CDK2;LYN GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1;CHRM2 GO:0007165| signal transduction MAP2K1;CHRM4;BCR;SRC;CHRM3;LYN;CHRM2;CHRM1 GO:0008283| cell proliferation SRC;CHRM4;CHRM1;CHRM3 GO:0006464| protein modification process ABL1;CHRM1;CHRM3 5180:[DB06616 DB01946] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01946|3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione PDPK1;DMPK common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PDPK1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;PDPK1 GO:0030036| actin cytoskeleton organization PDPK1;BCR;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway PDPK1;LYN;SRC GO:0032148| activation of protein kinase B activity SRC;PDPK1 GO:0043304| regulation of mast cell degranulation LYN;PDPK1 GO:0018105| peptidyl-serine phosphorylation SRC;DMPK;CAMK2G;PDPK1;CDK2 GO:0035556| intracellular signal transduction LYN;PDPK1;CAMK2G;SRC;BCR GO:0018107| peptidyl-threonine phosphorylation CAMK2G;PDPK1;MAP2K1 GO:0038095| LYN;PDPK1 GO:0016477| cell migration SRC;PDPK1 GO:0046777| protein autophosphorylation CAMK2G;PDPK1;LYN;ABL1;BCR;SRC;HCK GO:0006468| protein phosphorylation CAMK2G;PDPK1;LYN;CDK2;DMPK;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0032869| cellular response to insulin stimulus PDPK1;SRC GO:0030168| platelet activation PDPK1;LYN;SRC GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;PDPK1;DMPK;MAP3K2 GO:0031295| T cell costimulation SRC;PDPK1;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol PDPK1;ABL1 5181:[DB06616 DB09535] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09535|Octocrylene ESR1;ESR2 common genes common pathways GO:0007165| signal transduction ESR2;BCR;SRC;MAP2K1;ESR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1;ESR2 GO:0060065| uterus development SRC;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;ESR2;MAP3K2;ESR1;CDK2 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 5182:[DB06616 DB04021] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04021|MF268 ACHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0006260| DNA replication ACHE;CDK2 5183:[DB06616 DB09045] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09045|Dulaglutide GLP1R common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;ABL1 GO:0007165| signal transduction GLP1R;LYN;SRC;BCR;MAP2K1 5184:[DB06616 DB06307] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06307|Apoptone BCL2 common genes common pathways GO:0042981| regulation of apoptotic process BCL2;MAP3K2;MAP2K1;MAP2K2 GO:0006974| response to DNA damage stimulus CDK2;LYN;BCL2;ABL1 GO:0008284| positive regulation of cell proliferation HCK;BCL2;CDK2;LYN GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;BCL2;SRC GO:0042542| response to hydrogen peroxide BCL2;SRC GO:0051726| regulation of cell cycle BCL2;BCR;SRC;ABL1 GO:0043066| negative regulation of apoptotic process SRC;HCK;BCL2 GO:0042493| response to drug ABCB1;SRC;LYN;BCL2 GO:0051902| negative regulation of mitochondrial depolarization SRC;BCL2 GO:0010506| regulation of autophagy ABL1;BCL2 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2 GO:0051924| regulation of calcium ion transport BCL2;CAMK2G GO:0001782| B cell homeostasis LYN;BCL2 GO:2000811| negative regulation of anoikis SRC;BCL2 GO:0071456| cellular response to hypoxia BCL2;SRC GO:0045930| negative regulation of mitotic cell cycle BCL2;ABL1 GO:0098609| BCL2;SRC GO:0003014| renal system process BCL2;BCR GO:0030097| hemopoiesis LYN;BCL2 GO:0048536| spleen development BCL2;ABL1 GO:0048538| thymus development MAP2K1;ABL1;BCL2 GO:0006979| response to oxidative stress ABL1;BCL2 GO:0042100| B cell proliferation ABL1;BCL2 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;BCL2 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0006915| apoptotic process BCL2;ABL1 GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;BCR GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;BCL2 GO:0008283| cell proliferation SRC;BCL2 GO:0006470| protein dephosphorylation BCL2;CAMK2G GO:0009636| response to toxin BCL2;LYN GO:0008285| negative regulation of cell proliferation LYN;BCL2;MAP2K1 GO:0014911| positive regulation of smooth muscle cell migration BCL2;SRC GO:0030336| negative regulation of cell migration BCR;BCL2 GO:0009791| post-embryonic development BCL2;ABL1 GO:0050853| B cell receptor signaling pathway ABL1;BCL2;LYN 5185:[DB06616 DB09105] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09105|Asfotase Alfa S1PR1 common genes common pathways GO:0007165| signal transduction LYN;S1PR1;MAP2K1;BCR;SRC GO:0007420| brain development BCR;S1PR1 GO:0043547| positive regulation of GTPase activity S1PR1;BCR GO:0030335| positive regulation of cell migration LYN;S1PR1 GO:0030182| neuron differentiation MAP2K1;ABL1;S1PR1 GO:0016477| cell migration S1PR1;SRC GO:0006935| chemotaxis S1PR1;MAP2K1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;S1PR1;HCK GO:0030155| regulation of cell adhesion S1PR1;ABL1 GO:0007155| cell adhesion S1PR1;ABL1;HCK;SRC GO:0045124| regulation of bone resorption S1PR1;SRC 5186:[DB06616 DB12130] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes CYP2C8 common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0042127| regulation of cell proliferation ALK;SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation ALK;LYN;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2B6 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2C8;CYP3A4;CYP2B6 GO:0006082| organic acid metabolic process CYP2C8 GO:0007399| nervous system development CAMK2G;ALK GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;ALK;MAP3K2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4;CYP2B6 GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;CYP2C19;CYP2C8;CYP3A5 GO:0008202| steroid metabolic process CYP3A5;CYP2C19;CYP2C8;CYP3A4;CYP2B6 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;ALK GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ALK;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;ALK;CAMK2G;LYN;CDK2 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A3;CYP2B6;CYP3A4 GO:0007420| brain development BCR;ALK GO:0007165| signal transduction LYN;ALK;MAP2K1;SRC;BCR GO:0002933| CYP3A5;CYP2C8;CYP3A4 GO:0008283| cell proliferation ALK;SRC GO:0000187| activation of MAPK activity ALK;MAP3K2;MAP2K2;MAP2K1 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;ALK;CAMK2G;LYN GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 5187:[DB06616 DB06325] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06325|Pegpleranib PDGFB common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;PDGFB GO:0010628| positive regulation of gene expression PDGFB;MAP2K1;SRC GO:0045892| negative regulation of transcription, DNA-dependent PDGFB;SRC GO:0014911| positive regulation of smooth muscle cell migration SRC;PDGFB GO:0043406| positive regulation of MAP kinase activity PDGFB;SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity PDGFB;LYN;SRC GO:0030335| positive regulation of cell migration LYN;PDGFB GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;PDGFB;CDK2;CAMK2G;MAP3K2 GO:0030097| hemopoiesis PDGFB;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2;PDGFB GO:0010629| negative regulation of gene expression PDGFB;MAP2K1;MAP2K2 GO:0045737| positive regulation of cyclin-dependent protein kinase activity PDGFB;SRC GO:0000165| MAPKKK cascade CAMK2G;PDGFB;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade PDGFB;SRC GO:0031954| positive regulation of protein autophosphorylation PDGFB;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;PDGFB GO:0048008| platelet-derived growth factor receptor signaling pathway SRC;BCR;ABL1;PDGFB GO:0007275| multicellular organismal development PDGFB;CDK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation LYN;PDGFB;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:2000573| positive regulation of DNA biosynthetic process SRC;PDGFB GO:0002576| platelet degranulation PDGFB;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;PDGFB GO:0008284| positive regulation of cell proliferation HCK;PDGFB;LYN;CDK2 GO:0007507| heart development MAP2K1;PDGFB GO:0032148| activation of protein kinase B activity PDGFB;SRC 5188:[DB06616 DB07286] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07286|BMS-564929 AR common genes common pathways GO:0042327| positive regulation of phosphorylation LYN;AR GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0051259| protein oligomerization CAMK2G;AR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;AR;MAP2K2;SRC;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;AR GO:0006810| transport AR;ABCB1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC 5189:[DB06616 DB04620] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04620|Cycloleucine GRIN1 common genes common pathways GO:0048013| ephrin receptor signaling pathway SRC;GRIN1;LYN GO:0065009| regulation of molecular function GRIN1;CAMK2G GO:0000165| MAPKKK cascade GRIN1;CAMK2G;MAP2K1;MAP2K2 GO:0006816| calcium ion transport CAMK2G;GRIN1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;GRIN1 5190:[DB06616 DB01332] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways GO:0006810| transport ABCB1;SLC15A1 GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A8;SLC15A1;SLC22A6;ABCB1 5191:[DB06616 DB07344] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways GO:0006629| lipid metabolic process CYP3A4;MCAT 5192:[DB06616 DB03923] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03923|Feruloyl Coenzyme A COMTD1 common genes common pathways 5193:[DB06616 DB07394] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07394|AUROVERTIN B ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 5194:[DB06616 DB05192] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05192|MB07811 THRB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;CDK2 GO:0006355| regulation of transcription, DNA-dependent THRB;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;THRB 5195:[DB06616 DB09341] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09341|Dextrose, unspecified form HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus SLC2A1;MAP3K2 GO:0016310| phosphorylation MAP2K1;HCK;BCR;HK1;MAP2K2;SRC;ABL1;MAP3K2;GCK;LYN;CDK2;CAMK2G GO:0032869| cellular response to insulin stimulus SLC2A4;GCK;SRC GO:0071456| cellular response to hypoxia SLC2A4;SRC GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0055085| transmembrane transport SLC2A3;SLC2A4;SLC2A12;SLC2A9;SLC2A8;SLC2A1;SLC2A11;SLC5A1;SLC2A7;SLC2A2;SLC2A6;ABCB1;SLC2A10 GO:0032868| response to insulin stimulus SLC2A1;LYN 5196:[DB06616 DB04519] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0032868| response to insulin stimulus PPARA;LYN GO:0055085| transmembrane transport SLC22A8;SLC22A6;SLC22A11;ABCB1 GO:0006629| lipid metabolic process PPARA;CYP3A4 GO:0007507| heart development MAP2K1;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;CDK2 GO:0050728| negative regulation of inflammatory response PPARA;BCR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARA;MAP3K2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent PPARA;ABL1 5197:[DB06616 DB03664] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03664|UP5 CMPK1 common genes common pathways GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;CMPK1;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 5198:[DB06616 DB08088] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0008284| positive regulation of cell proliferation HCK;AR;LYN;CDK2 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0051259| protein oligomerization CAMK2G;AR GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;SRC;MAP2K2;AR GO:0007165| signal transduction AR;BCR;SRC;MAP2K1;LYN GO:0006810| transport AR;ABCB1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC 5199:[DB06616 DB08740] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08740|CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE CTSD common genes common pathways GO:0006914| autophagy CTSD;ABL1 5200:[DB06616 DB00191] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;MAOB;SLC6A2;LYN;SRC;ABCB1;SLC6A4;SLC6A3 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;MAOB;MAOA;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;MAOB;BCR GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;SRC;SLC6A4 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;CYP1A2;LYN GO:0009636| response to toxin SLC6A4;MAOB;LYN GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A4;SLC6A3 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0007420| brain development BCR;SLC6A4 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006810| transport SLC6A2;ABCB1 5201:[DB06616 DB06650] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06650|Ofatumumab MS4A1 common genes common pathways GO:0042100| B cell proliferation ABL1;MS4A1 5202:[DB06616 DB00371] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0009791| post-embryonic development GABRG2;ABL1 GO:0009636| response to toxin GABRB1;LYN GO:0007165| signal transduction GABRP;LYN;GABRA6;GABRD;GABRA5;GABRB1;GABRQ;GABRE;GABRB3;MAP2K1;BCR;SRC GO:0007420| brain development BCR;GABRA5 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0097267| CYP2C19;CYP2C8 GO:0006810| transport ABCB1;GABRB3;GABRA3;GABRG2;GABRA5;GABRB1;GABRD;GABRB2;GABRA6;GABRA4;GABRA1 GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19;CYP2C8 GO:0042493| response to drug CYP2E1;LYN;ABCB1;SRC;GABRG3 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 5203:[DB06616 DB03456] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03456|N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 5204:[DB06616 DB04409] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways GO:0010595| positive regulation of endothelial cell migration FGF1;ABL1 GO:0030335| positive regulation of cell migration LYN;FGF1 GO:0034605| cellular response to heat LYN;FGF1 GO:0030154| cell differentiation FGF1;CAMK2G;HCK GO:0007165| signal transduction LYN;FGF1;MAP2K1;SRC;BCR GO:1902533| SRC;FGF1 GO:0008283| cell proliferation FGF1;SRC GO:0000187| activation of MAPK activity MAP3K2;FGF1;MAP2K1;MAP2K2 GO:0043406| positive regulation of MAP kinase activity FGF1;SRC GO:0007275| multicellular organismal development FGF1;CAMK2G;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;FGF1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;FGF1 GO:0032148| activation of protein kinase B activity SRC;FGF1 GO:0001934| positive regulation of protein phosphorylation ABL1;FGF1;LYN GO:0000165| MAPKKK cascade FGF1;CAMK2G;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;FGF1 5205:[DB06616 DB02509] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02509|Farnesol MAOB;NR1H4;MAOB common genes common pathways GO:0045087| innate immune response SRC;HCK;ABL1;NR1H4;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;CDK2 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NR1H4 GO:0071398| cellular response to fatty acid NR1H4;SRC GO:0043066| negative regulation of apoptotic process NR1H4;HCK;SRC GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade NR1H4;ABL1 GO:0046628| positive regulation of insulin receptor signaling pathway NR1H4;SRC GO:0006954| inflammatory response NR1H4;LYN;HCK GO:0050728| negative regulation of inflammatory response NR1H4;BCR GO:0055114| oxidation-reduction process CYP2C8;MAOB;CYP3A4 GO:0042493| response to drug LYN;MAOB;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1H4 GO:0007165| signal transduction LYN;NR1H4;MAP2K1;BCR;SRC GO:0002376| immune system process LYN;NR1H4;HCK;SRC GO:0009636| response to toxin LYN;MAOB 5206:[DB06616 DB08560] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0010033| response to organic substance CDK2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0014070| response to organic cyclic compound LYN;PPARG GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;PPARG GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;PPARG;CDK2;MAP3K2 GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045087| innate immune response LYN;PPARG;HCK;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0007507| heart development PPARG;MAP2K1 5207:[DB06616 DB07917] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways GO:0007165| signal transduction BCR;SRC;HPGDS;MAP2K1;LYN GO:0006629| lipid metabolic process HPGDS;CYP3A4 5208:[DB06616 DB03384] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03384|Fica CASP7 common genes common pathways GO:0006915| apoptotic process CASP7;ABL1 5209:[DB06616 DB07630] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07630|N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration LYN;F10 5210:[DB06616 DB00283] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00283|Clemastine HRH1;CYP2D6 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction SRC;BCR;MAP2K1;HRH1;LYN GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 5211:[DB06616 DB00931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00931|Metacycline ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0002576| platelet degranulation ALB;LYN 5212:[DB06616 DB05233] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05233|AP1081 ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007165| signal transduction ESR1;LYN;BCR;SRC;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;ESR1;CDK2;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0060065| uterus development ESR1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 5213:[DB06616 DB00903] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0030335| positive regulation of cell migration LYN;LEF1 GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0006810| transport SLC12A1;ABCB1 GO:0032869| cellular response to insulin stimulus SRC;GSTP1 GO:0006813| potassium ion transport SLC12A1;ATP1A1;CDK2 GO:0022408| negative regulation of cell-cell adhesion LEF1;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1;GSTP1 GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0009636| response to toxin LYN;GSTP1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0032872| regulation of stress-activated MAPK cascade GSTP1;MAP2K1;MAP2K2 GO:0042100| B cell proliferation LEF1;ABL1 GO:0055085| transmembrane transport SLC22A6;ABCB1;SLC12A1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;LEF1 GO:0046632| alpha-beta T cell differentiation ABL1;LEF1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;LEF1 GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0022407| regulation of cell-cell adhesion LEF1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ABL1 GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0006805| xenobiotic metabolic process CYP2C8;GSTP1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;SRC;GSTP1;HCK;LEF1 GO:0002576| platelet degranulation ALB;LYN GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;LEF1 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;GSTP1 GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter LEF1;CDK2 GO:0031667| response to nutrient levels SRC;GSTP1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;MAP3K2;LEF1 GO:0042493| response to drug SRC;ABCB1;LYN;ATP1A1 GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0006355| regulation of transcription, DNA-dependent LEF1;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;LEF1 5214:[DB06616 DB07789] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0043066| negative regulation of apoptotic process PLK1;HCK;SRC GO:0018105| peptidyl-serine phosphorylation PLK1;SRC;CDK2;CAMK2G GO:0051726| regulation of cell cycle ABL1;PLK1;BCR;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PLK1 GO:0043393| regulation of protein binding PLK1;SRC GO:0051301| cell division PLK1;CDK2 GO:0010389| regulation of G2/M transition of mitotic cell cycle PLK1;CDK2 GO:0007346| regulation of mitotic cell cycle MAP2K2;MAP2K1;PLK1;MAP3K2 GO:0000278| mitotic cell cycle ABL1;PLK1 GO:1900182| SRC;PLK1 GO:0031648| protein destabilization SRC;PLK1 GO:0051439| regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle CDK2;PLK1 GO:0016310| phosphorylation ABL1;PLK1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;MAP3K2 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;PLK1 GO:0007049| cell cycle CDK2;SRC;PLK1 GO:0008283| cell proliferation PLK1;SRC GO:0045184| establishment of protein localization PLK1;ABL1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1;CDK2 5215:[DB06616 DB06945] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways 5216:[DB06616 DB00856] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00856|Chlorphenesin CYP2B;CYP19A1;CYP3A4;XDH;PTGS2;BCHE common genes CYP3A4 common pathways GO:0034605| cellular response to heat LYN;PTGS2 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0070542| response to fatty acid SRC;PTGS2 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;BCHE;MAP2K1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0001933| negative regulation of protein phosphorylation XDH;LYN GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0060065| uterus development CYP19A1;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0006706| steroid catabolic process CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0010629| negative regulation of gene expression XDH;MAP2K2;MAP2K1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug BCHE;PTGS2;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP19A1;CYP3A4;PTGS2;XDH GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0006954| inflammatory response HCK;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 5217:[DB06616 DB02328] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02328|2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid CTH common genes common pathways GO:0043066| negative regulation of apoptotic process CTH;SRC;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CTH 5218:[DB06616 DB04491] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04491|Diisopropylphosphono Group CFB;DPP4 common genes common pathways GO:0043542| endothelial cell migration DPP4;ABL1 GO:0045087| innate immune response LYN;CFB;ABL1;HCK;SRC GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0008284| positive regulation of cell proliferation LYN;CDK2;DPP4;HCK GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0002376| immune system process LYN;CFB;HCK;SRC 5219:[DB06616 DB01089] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01089|Deserpidine SLC18A2 common genes common pathways GO:0009636| response to toxin SLC18A2;LYN GO:0055085| transmembrane transport ABCB1;SLC18A2 GO:0009791| post-embryonic development SLC18A2;ABL1 5220:[DB06616 DB13166] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13166|Zofenopril ACE common genes common pathways 5221:[DB06616 DB00861] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00861|Diflunisal PTGS2;PTGS1;UGT1A8;UGT1A9;TTR;ALB;SLC22A6 common genes common pathways GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0070542| response to fatty acid PTGS2;SRC GO:0017144| drug metabolic process CYP2C8;UGT1A8;UGT1A9;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;UGT1A8 GO:0034605| cellular response to heat LYN;PTGS2 GO:0006810| transport ABCB1;TTR GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance CDK2;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK;ALB GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4;UGT1A9 GO:0008284| positive regulation of cell proliferation HCK;PTGS2;LYN;CDK2 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0002576| platelet degranulation LYN;ALB GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1;PTGS2 GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0042493| response to drug LYN;PTGS2;SRC;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 5222:[DB06616 DB00995] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;PRDX5;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PRDX5;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;IKBKB;MAP3K2 GO:0006954| inflammatory response HCK;LYN;IKBKB;PRDX5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IKBKB GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;IKBKB GO:0034599| cellular response to oxidative stress PRDX5;ABL1 GO:0045087| innate immune response ABL1;SRC;HCK;LYN;IKBKB GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;IKBKB;CDK2 GO:0009615| response to virus SRC;IKBKB GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process IKBKB;PRDX5;ALB;SRC;HCK GO:0006915| apoptotic process ABL1;PRDX5 GO:0038095| LYN;IKBKB GO:0034614| cellular response to reactive oxygen species SRC;PRDX5 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;IKBKB;CDK2;LYN;CAMK2G;MAP3K2 GO:0016310| phosphorylation CAMK2G;IKBKB;LYN;CDK2;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0006979| response to oxidative stress ABL1;PRDX5 5223:[DB06616 DB08930] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes ABCB1;CYP3A4 common pathways GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP3A43;CYP2C8;CYP3A5 GO:2001225| regulation of chloride transport ABCB1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042493| response to drug ABCG2;ABCB1;SRC;LYN;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide BCR;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A7;UGT1A9;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCG2;SLC22A2;SLC22A6;SLC22A8 GO:0036378| CYP3A4 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport SLC22A2;ABCG2;ABCB1 GO:0014070| response to organic cyclic compound LYN;UGT1A1 GO:0009636| response to toxin LYN;SLC22A8 GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0010033| response to organic substance CDK2;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A7;UGT1A1;CYP3A4;CYP2C8;CYP3A5 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0017144| drug metabolic process UGT1A9;UGT1A1;CYP3A4;UGT1A3;CYP2C8 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 5224:[DB06616 DB11858] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways GO:0006816| calcium ion transport CYSLTR1;CAMK2G GO:0006935| chemotaxis MAP2K1;CYSLTR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CYSLTR2;ABL1;MAP2K1;MAP2K2;SRC GO:0007165| signal transduction CYSLTR1;BCR;SRC;MAP2K1;CYSLTR2;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CYSLTR1 5225:[DB06616 DB14132] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008285| negative regulation of cell proliferation ADORA2A;LYN;MAP2K1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0006915| apoptotic process ADORA2A;ABL1 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0007596| blood coagulation ADORA2A;LYN GO:0007165| signal transduction ADORA2A;LYN;SRC;BCR;MAP2K1 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0007417| central nervous system development SRC;ADORA2A;LYN GO:0051924| regulation of calcium ion transport CAMK2G;ADORA2A GO:0050728| negative regulation of inflammatory response BCR;ADORA2A GO:0006954| inflammatory response HCK;LYN;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0006909| phagocytosis HCK;ABL1;ADORA2A GO:0042493| response to drug SRC;ABCB1;CYP1A2;LYN;ADORA2A GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ABL1;ADORA2A GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR 5226:[DB06616 DB07257] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07257|4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione WEE1 common genes common pathways GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;WEE1;LYN;CDK2;CAMK2G GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;WEE1;CDK2;LYN GO:0007049| cell cycle SRC;CDK2;WEE1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;WEE1;CDK2 GO:0051726| regulation of cell cycle BCR;SRC;ABL1;WEE1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;WEE1;LYN GO:0051301| cell division CDK2;WEE1 GO:0000082| G1/S transition of mitotic cell cycle CDK2;WEE1;CAMK2G GO:0000278| mitotic cell cycle WEE1;ABL1 5227:[DB06616 DB07716] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07716|(4Z)-2,8:7,12:11,15:14,18:17,22-PENTAANHYDRO-4,5,6,9,10,13,19,20,21-NONADEOXY-D-ARABINO-D-ALLO-D-ALLO-DOCOSA-4,9,20-TRIENITOL IGKC common genes common pathways GO:0045087| innate immune response ABL1;HCK;SRC;LYN;IGKC GO:0050900| leukocyte migration SRC;LYN;IGKC GO:0038096| IGKC;LYN;SRC;HCK;ABL1 GO:0002250| adaptive immune response LYN;IGKC GO:0002376| immune system process IGKC;LYN;SRC;HCK GO:0038095| LYN;IGKC GO:0050853| B cell receptor signaling pathway ABL1;IGKC;LYN 5228:[DB06616 DB09070] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0007165| signal transduction LYN;ESR1;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0008202| steroid metabolic process STS;CYP3A4;SULT1A1;CYP2C8 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0006629| lipid metabolic process SULT1A1;STS;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;STS GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0006805| xenobiotic metabolic process CYP3A4;SULT1A1;CYP2C8 GO:0060065| uterus development SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;HSD3B2;HSD3B1;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;MAP2K2;SRC;MAP2K1 5229:[DB06616 DB09479] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09479|Rubidium Rb-82 FXYD2;ATP1A1;ATP1B1;ATP1B2;ATP1B3;ATP1A4;ATP1A2;ATP1A3 common genes common pathways GO:0006810| transport ATP1B2;ABCB1;ATP1B3;FXYD2 GO:0006813| potassium ion transport ATP1A4;ATP1B1;ATP1A2;CDK2;ATP1A3;ATP1A1;FXYD2;ATP1B2;ATP1B3 GO:0042493| response to drug ABCB1;SRC;ATP1A1;ATP1A3;LYN GO:0050900| leukocyte migration LYN;ATP1B1;ATP1B3;SRC;ATP1B2 GO:0042127| regulation of cell proliferation FXYD2;ABL1;SRC GO:0071300| cellular response to retinoic acid LYN;ATP1A3 GO:0007155| cell adhesion SRC;ATP1B2;HCK;ABL1;ATP1B1 GO:0071260| cellular response to mechanical stimulus ATP1A1;ATP1A2;MAP3K2 5230:[DB06616 DB02462] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02462|Thiocoumarin NOS2 common genes common pathways GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NOS2 GO:0010629| negative regulation of gene expression NOS2;MAP2K1;MAP2K2 5231:[DB06616 DB02395] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02395|3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol NQO1 common genes common pathways GO:0006979| response to oxidative stress NQO1;ABL1 GO:0009636| response to toxin LYN;NQO1 GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1 GO:0043066| negative regulation of apoptotic process SRC;HCK;NQO1 GO:0006805| xenobiotic metabolic process CYP3A4;NQO1;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;NQO1;CYP2C8 GO:0051602| response to electrical stimulus SRC;NQO1 5232:[DB06616 DB00964] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0042493| response to drug SRC;ADRA1A;ABCB1;LYN GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;ADRA1A;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;ADRA2A;HCK GO:0032148| activation of protein kinase B activity ADRA2B;SRC;ADRA2A GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;ADRA2B GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ADRA1A;ABL1 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction LYN;ADRA2B;ADRA1A;SRC;BCR;MAP2K1;ADRA2A GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0030168| platelet activation SRC;ADRA2A;ADRA2B;LYN GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ABL1 5233:[DB06616 DB00487] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0043065| positive regulation of apoptotic process TOP2A;ABL1;SRC GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006974| response to DNA damage stimulus LYN;CDK2;TOP2A;ABL1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug LYN;CYP1A2;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 5234:[DB06616 DB07154] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;DPP4;LYN GO:0008284| positive regulation of cell proliferation DPP4;CDK2;LYN;HCK GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 5235:[DB06616 DB13881] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13881|Tisagenlecleucel CD19 common genes common pathways GO:0050853| B cell receptor signaling pathway ABL1;CD19;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol CD19;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade CD19;SRC 5236:[DB06616 DB04233] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04233|(Hydroxyethyloxy)Tri(Ethyloxy)Octane CLPS;PNLIP;RHO common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;RHO GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;RHO;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0006629| lipid metabolic process CLPS;PNLIP;CYP3A4 5237:[DB06616 DB03703] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03703|Cyclohexanol ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ADH1B;CYP3A4 5238:[DB06616 DB09203] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09203|Synephrine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CAMK2G;CDK2 GO:0035556| intracellular signal transduction ADRA1B;BCR;ADRA1A;SRC;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation ADRA1D;LYN;CDK2;HCK GO:0042493| response to drug ADRA1A;SRC;ABCB1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A;ADRA1D GO:0007165| signal transduction LYN;ADRA1D;ADRA1B;MAP2K1;SRC;ADRA1A;BCR GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;ADRA1A;MAP2K2;ABL1 GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A 5239:[DB06616 DB13132] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13132|Artemisinin CYP2B6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP2B6;CYP3A4 GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2B6 GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP2C8 5240:[DB06616 DB04852] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04852|Implitapide MTTP common genes common pathways GO:0006629| lipid metabolic process CYP3A4;MTTP 5241:[DB06616 DB05920] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05920|RTA 744 TOP2A common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;ABL1;TOP2A GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;TOP2A 5242:[DB06616 DB08163] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08163|5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine AMD1 common genes common pathways 5243:[DB06616 DB03894] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03894|N-Propargyl-1(S)-Aminoindan MAOB;MAOB common genes common pathways GO:0009636| response to toxin LYN;MAOB GO:0042493| response to drug MAOB;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 GO:0032496| response to lipopolysaccharide MAOB;BCR 5244:[DB06616 DB05938] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05938|Edonerpic APP common genes common pathways GO:0045931| positive regulation of mitotic cell cycle APP;ABL1 GO:0043393| regulation of protein binding SRC;APP GO:0042327| positive regulation of phosphorylation APP;LYN GO:0006897| endocytosis ABL1;APP GO:0002576| platelet degranulation APP;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;APP GO:0007399| nervous system development APP;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0045087| innate immune response LYN;APP;ABL1;HCK;SRC GO:0007155| cell adhesion APP;ABL1;HCK;SRC GO:1901216| ABL1;APP GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;APP GO:0001934| positive regulation of protein phosphorylation APP;LYN;ABL1 GO:0050885| neuromuscular process controlling balance APP;ABL1;BCR GO:0051897| positive regulation of protein kinase B signaling cascade SRC;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;APP;ABL1;SRC GO:0007204| elevation of cytosolic calcium ion concentration APP;ABL1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;APP;MAP3K2 GO:0006979| response to oxidative stress APP;ABL1 GO:0030900| forebrain development SRC;APP GO:0031175| neuron projection development LYN;APP GO:0006915| apoptotic process APP;ABL1 GO:0000187| activation of MAPK activity APP;MAP3K2;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;APP GO:0010628| positive regulation of gene expression MAP2K1;SRC;APP GO:1900272| APP;ABL1 GO:0008285| negative regulation of cell proliferation APP;LYN;MAP2K1 5245:[DB06616 DB12610] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12610|Ebselen EPHX2 common genes common pathways GO:0006954| inflammatory response HCK;EPHX2;LYN GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;EPHX2 GO:0010628| positive regulation of gene expression EPHX2;SRC;MAP2K1 GO:0009636| response to toxin EPHX2;LYN GO:0017144| drug metabolic process EPHX2;CYP3A4;CYP2C8 5246:[DB06616 DB07063] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07063|{3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 GO:0055114| oxidation-reduction process CYP3A4;AKR1B1;CYP2C8 GO:0010033| response to organic substance CDK2;AKR1B1 5247:[DB06616 DB11397] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation TF;LYN;ALB GO:0042493| response to drug ABCB1;SRC;LYN;BCHE GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 5248:[DB06616 DB00600] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00600|Monobenzone TYR common genes common pathways GO:0048538| thymus development TYR;ABL1;MAP2K1 GO:0008283| cell proliferation TYR;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;TYR 5249:[DB06616 DB03889] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 5250:[DB06616 DB01831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;WARS;LYN GO:0010628| positive regulation of gene expression WARS;MAP2K1;SRC GO:0001933| negative regulation of protein phosphorylation LYN;WARS 5251:[DB06616 DB14527] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14527|Chromic nitrate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYB5A;CYP3A4;CYP2C8 GO:0002576| platelet degranulation TF;LYN 5252:[DB06616 DB02637] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02637|Oxaloacetate Ion CS;mdh;SPR common genes common pathways GO:0055114| oxidation-reduction process SPR;CYP3A4;CYP2C8 5253:[DB06616 DB08435] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways GO:0009612| response to mechanical stimulus PPARG;SRC GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0007507| heart development MAP2K1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug LYN;PPARG;ABCB1;SRC GO:0007165| signal transduction PPARG;LYN;SRC;BCR;MAP2K1 GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0010033| response to organic substance PPARG;CDK2 GO:0014070| response to organic cyclic compound LYN;PPARG 5254:[DB06616 DB07580] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07580|BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE APCS common genes common pathways GO:0045087| innate immune response LYN;APCS;ABL1;SRC;HCK 5255:[DB06616 DB06410] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0007275| multicellular organismal development VDR;CDK2;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;VDR GO:0055114| oxidation-reduction process CYP27A1;CYP3A4;CYP2C8 GO:0006816| calcium ion transport VDR;CAMK2G GO:0007165| signal transduction VDR;MAP2K1;SRC;BCR;LYN GO:0010628| positive regulation of gene expression MAP2K1;VDR;SRC GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC GO:0008285| negative regulation of cell proliferation VDR;MAP2K1;LYN 5256:[DB06616 DB01064] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:1903351| ABL1;MAPK1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity MAPK1;HCK GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A1;CYP2C8 GO:0051056| regulation of small GTPase mediated signal transduction PIK3R2;BCR GO:0007165| signal transduction BCR;ADRB1;SRC;MAP2K1;PIK3R1;ADRB3;PIK3R2;MAPK1;ADRB2;LYN GO:0006979| response to oxidative stress SOD1;ABL1 GO:1900034| CAMK2G;MAPK1 GO:0030878| thyroid gland development MAP2K1;MAPK1 GO:0045453| bone resorption ADRB2;SRC GO:0048538| thymus development MAPK1;SOD1;MAP2K1;ABL1 GO:0030168| platelet activation SRC;PIK3R1;MAPK1;LYN GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;MAPK1;ABL1;PIK3R1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0032869| cellular response to insulin stimulus PIK3R2;PIK3R1;SRC GO:0043547| positive regulation of GTPase activity BCR;ADRB1;PIK3R2 GO:0030335| positive regulation of cell migration MAPK1;LYN;PIK3R1 GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAPK1;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0031295| T cell costimulation SRC;PIK3R1;LYN GO:0010033| response to organic substance CDK2;SOD1;CYP1A1 GO:0007049| cell cycle SRC;CDK2;MAPK1 GO:0007411| axon guidance PIK3R1;SRC;MAPK1 GO:0090170| regulation of Golgi inheritance MAP2K2;MAP2K1;MAPK1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;SRC;MAPK1 GO:0034614| cellular response to reactive oxygen species SRC;MAPK1 GO:0050853| B cell receptor signaling pathway MAPK1;LYN;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;MAP2K2;SRC GO:0006915| apoptotic process ABL1;MAPK1 GO:0032872| regulation of stress-activated MAPK cascade MAPK1;MAP2K1;MAP2K2 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAPK1;MAP3K2;SOD1 GO:0018107| peptidyl-threonine phosphorylation MAPK1;CAMK2G;MAP2K1 GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0009636| response to toxin CYP1A1;LYN;MAPK1 GO:0008283| cell proliferation CYP1A1;SRC GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway MAPK1;LYN GO:0038095| PIK3R1;PIK3R2;MAPK1;LYN GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis PIK3R1;ABL1 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;MAPK1 GO:0007507| heart development MAPK1;MAP2K1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0035556| intracellular signal transduction LYN;CAMK2G;MAPK1;SRC;BCR GO:0048010| vascular endothelial growth factor receptor signaling pathway PIK3R2;SRC;PIK3R1 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;MAPK1;LYN GO:0043066| negative regulation of apoptotic process PIK3R1;SRC;HCK;SOD1 GO:0002576| platelet degranulation LYN;SOD1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;SOD1 GO:0018105| peptidyl-serine phosphorylation SRC;MAPK1;CAMK2G;CDK2 GO:0042542| response to hydrogen peroxide SOD1;SRC GO:0009615| response to virus CYP1A1;SRC GO:0008284| positive regulation of cell proliferation HCK;MAPK1;LYN;CDK2 GO:0006935| chemotaxis MAP2K1;MAPK1 GO:0048678| response to axon injury SOD1;LYN GO:0034599| cellular response to oxidative stress SOD1;ABL1 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A1;MAPK1;BCR GO:0000165| MAPKKK cascade MAPK1;CAMK2G;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade PIK3R1;SRC;PIK3R2 GO:0038096| MAPK1;PIK3R2;LYN;HCK;SRC;ABL1;PIK3R1 GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1;MAPK1 GO:2000641| regulation of early endosome to late endosome transport MAPK1;MAP2K2;SRC;MAP2K1 GO:0038128| PIK3R1;SRC GO:0016032| viral reproduction PIK3R1;SRC;HCK;LYN;MAPK1 GO:0070371| ERK1 and ERK2 cascade MAPK1;MAP2K2;MAP2K1 GO:0060324| face development MAPK1;MAP2K1 GO:0060425| lung morphogenesis MAP2K1;MAPK1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;SOD1;CYP2C8 GO:0050900| leukocyte migration PIK3R2;LYN;SRC;PIK3R1 GO:0060440| trachea formation MAPK1;MAP2K1 GO:0010506| regulation of autophagy PIK3R2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAPK1;MAP3K2;CDK2;SRC;MAP2K2;MAP2K1 GO:0007173| epidermal growth factor receptor signaling pathway PIK3R1;ABL1;SRC GO:0031667| response to nutrient levels SRC;SOD1 GO:0042493| response to drug ABCB1;SRC;CYP1A1;SOD1;LYN GO:0006355| regulation of transcription, DNA-dependent MAPK1;ABL1 5257:[DB06616 DB03948] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03948|6-Chloropurine Riboside, 5'-Monophosphate IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process IMPDH2;CYP3A4;IMPDH1;CYP2C8 5258:[DB06616 DB06721] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06721|Gimatecan SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;ABCB1 5259:[DB06616 DB04853] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04853|Binodenoson ADORA2A common genes common pathways GO:0051924| regulation of calcium ion transport CAMK2G;ADORA2A GO:0006954| inflammatory response HCK;ADORA2A;LYN GO:0050728| negative regulation of inflammatory response ADORA2A;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;SRC GO:0006909| phagocytosis ABL1;HCK;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ABL1;ADORA2A GO:0042493| response to drug ABCB1;SRC;LYN;ADORA2A GO:0007165| signal transduction ADORA2A;LYN;SRC;BCR;MAP2K1 GO:0007417| central nervous system development SRC;LYN;ADORA2A GO:0008285| negative regulation of cell proliferation LYN;ADORA2A;MAP2K1 GO:0006915| apoptotic process ABL1;ADORA2A GO:0007596| blood coagulation LYN;ADORA2A 5260:[DB06616 DB01947] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01947|RU78262 SRC common genes SRC common pathways GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0035635| entry of bacterium into host cell SRC GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0035556| intracellular signal transduction SRC;BCR;CAMK2G;LYN GO:0071398| cellular response to fatty acid SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0007155| cell adhesion ABL1;HCK;SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0086098| SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0016032| viral reproduction LYN;HCK;SRC GO:0038096| SRC;HCK;ABL1;LYN GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0038128| SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0042493| response to drug SRC;ABCB1;LYN GO:0038083| LYN;HCK;SRC;ABL1 GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0050900| leukocyte migration LYN;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0034332| adherens junction organization SRC GO:0002376| immune system process HCK;SRC;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0036120| SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0071456| cellular response to hypoxia SRC GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;LYN;CAMK2G GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0007411| axon guidance SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1 GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC 5261:[DB06616 DB02515] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways GO:0032868| response to insulin stimulus LYN;PFKFB1 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;PFKFB1;CAMK2G;MAP3K2 5262:[DB06616 DB03486] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CANT1 GO:0007165| signal transduction BCR;SRC;MAP2K1;CANT1;LYN 5263:[DB06616 DB07747] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07747|(3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 5264:[DB06616 DB14529] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14529|Chromium nicotinate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYB5A;CYP3A4 GO:0002576| platelet degranulation TF;LYN 5265:[DB06616 DB01678] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01678|RU84687 SRC common genes SRC common pathways GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR GO:0071398| cellular response to fatty acid SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response ABL1;SRC;HCK;LYN GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway SRC;BCR;ABL1 GO:0045056| transcytosis SRC GO:0086098| SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0016032| viral reproduction LYN;SRC;HCK GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0038128| SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0038096| HCK;SRC;ABL1;LYN GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071498| cellular response to fluid shear stress SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0042493| response to drug SRC;ABCB1;LYN GO:0038083| LYN;ABL1;SRC;HCK GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2 GO:0050900| leukocyte migration LYN;SRC GO:0034332| adherens junction organization SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0002376| immune system process LYN;SRC;HCK GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0036120| SRC GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0098609| SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN GO:0051895| negative regulation of focal adhesion assembly SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle CDK2;SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC 5266:[DB06616 DB10772] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways GO:0001843| neural tube closure ABL1;TGFB1 GO:0000186| activation of MAPKK activity MAP3K2;EGFR GO:0045930| negative regulation of mitotic cell cycle EGFR;ABL1;TGFB1;TNF GO:0002513| tolerance induction to self antigen LYN;TGFB1 GO:0030168| platelet activation LYN;SRC;IL6 GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;EGFR;PDGFRA;FGFR2;ABL1;TGFB1;MAP3K2;CAMK2G;LYN;CDK2;TGFBR2 GO:1903800| MAP2K2;MAP2K1;EGFR;TGFB1 GO:0030154| cell differentiation HCK;TGFBR2;CAMK2G;FGF1;VEGFA GO:0071456| cellular response to hypoxia VEGFA;SRC GO:0007204| elevation of cytosolic calcium ion concentration PDGFRA;ABL1 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;TGFB1;PDGFRA;SRC GO:0098609| EGFR;SRC GO:0030335| positive regulation of cell migration FGF1;LYN;VEGFA;TGFB1;IL1B;PDGFRA;EGFR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;EGFR;PDGFRA;HCK GO:0034605| cellular response to heat FGF1;LYN GO:0010595| positive regulation of endothelial cell migration ABL1;FGF1;VEGFA GO:0016310| phosphorylation FGFR2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;EGFR;PDGFRA;CAMK2G;CDK2;LYN;TGFBR2;MAP3K2 GO:1902533| SRC;FGF1 GO:1900182| TGFB1;SRC GO:0007050| cell cycle arrest ABL1;IFNG;MAP2K1;TGFB1 GO:0065009| regulation of molecular function CAMK2G;CSF2RA GO:0070372| regulation of ERK1 and ERK2 cascade LYN;EGFR;FGFR2;IL1B GO:0007165| signal transduction LYN;FGF1;MAP2K1;EGFR;BCR;SRC;IL1B GO:0007420| brain development TGFBR2;BCR GO:0051222| positive regulation of protein transport TNF;SRC GO:0006979| response to oxidative stress EGFR;ABL1 GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;IFNG;HCK GO:0022408| negative regulation of cell-cell adhesion ABL1;TGFB1 GO:0006915| apoptotic process FGFR2;IFNG;ABL1;IL1B;TGFB1;TGFBR2 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;IL1B;MAP3K2;TNF;FGF1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;TGFBR2;TGFB1 GO:0045785| positive regulation of cell adhesion TNF;VEGFA;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TGFB1;VEGFA;FGFR2;ABL1;MAP2K1;PDGFRA;EGFR;MAP2K2;SRC GO:0018107| peptidyl-threonine phosphorylation MAP2K1;TGFBR2;CAMK2G GO:0016477| cell migration TGFB1;SRC GO:0014070| response to organic cyclic compound TGFB1;LYN;TGFBR2;EGFR GO:0031175| neuron projection development IL6;LYN GO:0008283| cell proliferation FGF1;TGFB1;SRC;EGFR GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0010033| response to organic substance TNF;CDK2;TGFBR2;TGFB1 GO:0008285| negative regulation of cell proliferation MAP2K1;IL6;IL1B;TGFB1;LYN;TGFBR2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway FGFR2;SRC GO:0050766| positive regulation of phagocytosis TNF;BCR;IL1B GO:0045892| negative regulation of transcription, DNA-dependent SRC;IFNG;TGFB1;TNF GO:0043406| positive regulation of MAP kinase activity FGF1;TNF;VEGFA;TGFB1;SRC;EGFR GO:0070301| cellular response to hydrogen peroxide ABL1;IL6 GO:0043407| negative regulation of MAP kinase activity LYN;IL1B GO:0010628| positive regulation of gene expression IL6;MAP2K1;SRC;IL1B;IFNG;TGFB1;VEGFA;TNF GO:0006928| cellular component movement IFNG;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC;PDGFRA;EGFR GO:0009791| post-embryonic development FGFR2;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity IFNG;MAP2K1;SRC;MAP2K2 GO:0046777| protein autophosphorylation FGFR2;ABL1;EGFR;PDGFRA;HCK;BCR;SRC;LYN;CAMK2G GO:0007498| mesoderm development VEGFA;HCK GO:0007275| multicellular organismal development PDGFRA;EGFR;CDK2;TNF;CAMK2G;FGF1;VEGFA GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;CSF2RA;SRC;MAP2K1;HCK;EGFR;PDGFRA;FGFR2;ABL1;FGF1;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IFNG;IL6;LYN;VEGFA GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;ABL1;TNF GO:0042472| inner ear morphogenesis BCR;FGFR2 GO:0001933| negative regulation of protein phosphorylation LYN;TGFB1 GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA GO:0048008| platelet-derived growth factor receptor signaling pathway PDGFRA;SRC;BCR;ABL1 GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;SRC;EGFR;TGFBR2;TNF;TGFB1 GO:0032496| response to lipopolysaccharide BCR;FGFR2;IL1B GO:0071260| cellular response to mechanical stimulus EGFR;IL1B;TGFB1;MAP3K2 GO:0050777| negative regulation of immune response LYN;TGFB1 GO:0007507| heart development TGFB1;TGFBR2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR2;IFNG;TNF;CDK2;VEGFA;TGFB1 GO:0008360| regulation of cell shape HCK;VEGFA GO:0032148| activation of protein kinase B activity FGF1;SRC GO:0010634| positive regulation of epithelial cell migration SRC;IFNG;TGFBR2 GO:0042981| regulation of apoptotic process MAP3K2;TGFB1;MAP2K1;MAP2K2 GO:0007399| nervous system development VEGFA;CAMK2G GO:0071300| cellular response to retinoic acid FGFR2;LYN GO:2000249| regulation of actin cytoskeleton reorganization TGFB1;PDGFRA;ABL1 GO:2000145| regulation of cell motility EGFR;ABL1 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;EGFR GO:0048010| vascular endothelial growth factor receptor signaling pathway VEGFA;SRC GO:0051272| positive regulation of cellular component movement VEGFA;LYN GO:0043066| negative regulation of apoptotic process VEGFA;IL6;HCK;EGFR;SRC GO:0042327| positive regulation of phosphorylation LYN;VEGFA;EGFR GO:0031663| lipopolysaccharide-mediated signaling pathway TGFB1;LYN;TNF;HCK;IL1B GO:0009612| response to mechanical stimulus TGFBR2;SRC GO:0071560| cellular response to transforming growth factor beta stimulus TGFB1;FGFR2;SRC GO:0050727| regulation of inflammatory response TNF;LYN;HCK GO:0002576| platelet degranulation LYN;VEGFA;TGFB1 GO:0043065| positive regulation of apoptotic process SRC;IL6;ABL1;TGFB1;TNF GO:0071222| cellular response to lipopolysaccharide SRC;BCR;IL6;ABL1;TNF GO:0009615| response to virus TNF;IFNG;SRC GO:0018105| peptidyl-serine phosphorylation TGFBR2;CDK2;CAMK2G;SRC GO:0006935| chemotaxis PDGFRA;MAP2K1 GO:0008284| positive regulation of cell proliferation VEGFA;TGFB1;FGF1;LYN;CDK2;TGFBR2;IL6;HCK;PDGFRA;EGFR;FGFR2;IFNG;IL1B GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;SRC GO:0060425| lung morphogenesis MAP2K1;TGFBR2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;VEGFA GO:0001934| positive regulation of protein phosphorylation TNF;LYN;FGF1;TGFB1;VEGFA;IL1B;ABL1;IFNG;EGFR GO:0023014| signal transduction via phosphorylation event TGFBR2;LYN GO:0050900| leukocyte migration IL1B;SRC;TNF;LYN;TGFB1 GO:0060440| trachea formation TGFBR2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;CDK2;TGFB1;MAP3K2;IL1B;MAP2K2;SRC;MAP2K1;IL6;EGFR GO:0007173| epidermal growth factor receptor signaling pathway ABL1;EGFR;SRC;TGFB1 GO:0038083| LYN;ABL1;SRC;EGFR;HCK GO:0010629| negative regulation of gene expression IFNG;MAP2K2;MAP2K1;TNF;VEGFA;TGFB1 GO:0042493| response to drug TGFBR2;LYN;TGFB1;SRC;ABCB1 GO:0014003| oligodendrocyte development LYN;TGFB1 GO:0000165| MAPKKK cascade TNF;CAMK2G;FGF1;TGFB1;IL1B;FGFR2;MAP2K1;PDGFRA;EGFR;CSF2RA;MAP2K2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;PDGFRA;EGFR;FGFR2;TGFB1;FGF1;TNF GO:0002250| adaptive immune response IFNG;LYN GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0009743| response to carbohydrate stimulus IL1B;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;IL6;ABL1;VEGFA;TGFB1;LYN GO:0031954| positive regulation of protein autophosphorylation VEGFA;SRC GO:0019221| cytokine-mediated signaling pathway CSF2RA;IL6;HCK;IL1B GO:0038128| EGFR;SRC GO:0016032| viral reproduction LYN;SRC;PDGFRA;HCK GO:0006954| inflammatory response TNF;LYN;TGFB1;IL1B;HCK;IL6 5267:[DB06616 DB02107] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 5268:[DB06616 DB08488] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08488|4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE F10 common genes common pathways GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration F10;LYN GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC 5269:[DB06616 DB07087] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07087|4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA2;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;ESR1;CDK2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;ESR1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0060065| uterus development ESR1;SRC 5270:[DB06616 DB04256] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways GO:0000186| activation of MAPKK activity MAP3K2;GRM1 GO:0007165| signal transduction SRC;BCR;MAP2K1;GRM1;LYN GO:0000187| activation of MAPK activity MAP3K2;GRM1;MAP2K2;MAP2K1 5271:[DB06616 DB06538] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06538|Robalzotan HTR1A common genes common pathways GO:0008283| cell proliferation HTR1A;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;HTR1A GO:0008284| positive regulation of cell proliferation HCK;HTR1A;LYN;CDK2 5272:[DB06616 DB08156] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways GO:0010033| response to organic substance CDK2;CA2 GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0071498| cellular response to fluid shear stress CA2;SRC 5273:[DB06616 DB14002] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14002|D-alpha-Tocopherol acetate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0006810| transport TTPA;ABCB1 GO:0030168| platelet activation PRKCA;PRKCB;SRC;LYN;DGKA GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0071456| cellular response to hypoxia SRC;HMOX1 GO:0032869| cellular response to insulin stimulus GCLC;SRC;GSTP1 GO:0006468| protein phosphorylation HCK;MAP2K1;PRKCB;SRC;MAP2K2;BCR;ABL1;PRKCA;MAP3K2;LYN;CDK2;CAMK2G GO:0008202| steroid metabolic process CYP3A4;NR1I2;CYP2C8 GO:0034605| cellular response to heat LYN;HMOX1 GO:0030335| positive regulation of cell migration PRKCA;LYN GO:0016310| phosphorylation ABL1;PRKCA;HCK;MAP2K1;PRKCB;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;DGKA GO:0010595| positive regulation of endothelial cell migration ABL1;PRKCA GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0070555| response to interleukin-1 SRC;PRKCA;GCLC GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0051321| meiotic cell cycle PPP2CA;CDK2 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;HMOX1 GO:0009725| response to hormone stimulus LYN;GCLC GO:0007165| signal transduction PRKCB;SRC;BCR;MAP2K1;NR1I2;LYN GO:0050861| positive regulation of B cell receptor signaling pathway LYN;PRKCB GO:0006979| response to oxidative stress SOD1;HMOX1;NQO1;GCLC;ABL1 GO:0048538| thymus development SOD1;ABL1;MAP2K1 GO:0002376| immune system process LYN;SRC;PRKCB;HCK GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;GSTP1;MAP2K2 GO:0006915| apoptotic process PPP2CA;PRKCB;ABL1;PRKCA;HMOX1 GO:0000187| activation of MAPK activity MAP3K2;SOD1;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;PRKCA;ABL1 GO:0045785| positive regulation of cell adhesion SRC;PRKCA GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0009636| response to toxin LYN;NQO1;TTPA;GSTP1 GO:0043200| response to amino acid stimulus LYN;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1;GSTP1 GO:0006470| protein dephosphorylation PPP2CB;CAMK2G;PPP2CA GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1;GCLC GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis HMOX1;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;SRC;GCLC GO:0008285| negative regulation of cell proliferation LYN;HMOX1;MAP2K1 GO:0010033| response to organic substance CDK2;SOD1;PPP2CA GO:0007411| axon guidance PRKCA;SRC GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0070301| cellular response to hydrogen peroxide ABL1;NQO1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;NR1I2 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;PPP2CA;MAP2K2;SRC GO:0050853| B cell receptor signaling pathway ABL1;PRKCB;LYN GO:0048678| response to axon injury LYN;SOD1 GO:0007498| mesoderm development HCK;PPP2CA GO:0034599| cellular response to oxidative stress SOD1;GSTP1;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;ABL1;PRKCB GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0045931| positive regulation of mitotic cell cycle PRKCA;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;GCLC GO:0006629| lipid metabolic process TTPA;CYP3A4 GO:0007155| cell adhesion ABL1;PRKCA;SRC;HCK GO:0030155| regulation of cell adhesion PPP2CA;ABL1 GO:0043066| negative regulation of apoptotic process GCLC;GSTP1;HCK;SRC;SOD1;NQO1 GO:0035556| intracellular signal transduction PRKCA;PRKCB;SRC;BCR;HMOX1;CAMK2G;LYN;DGKA GO:0006805| xenobiotic metabolic process CYP2C8;GSTP1;NR1I2;CYP3A4;NQO1 GO:0042542| response to hydrogen peroxide HMOX1;SOD1;PPP2CB;SRC GO:0018105| peptidyl-serine phosphorylation PRKCB;SRC;PRKCA;CDK2;CAMK2G GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;GSTP1 GO:1904528| PPP2CB;ABL1;PPP2CA GO:0043065| positive regulation of apoptotic process ABL1;SRC;SOD1;HMOX1 GO:0002576| platelet degranulation SOD1;LYN GO:0055114| oxidation-reduction process CYP3A4;HMOX1;NQO1;GSTO1;SOD1;CYP2C8;ALOX5 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;NR1I2;MAP2K1;SRC;MAP2K2;SEC14L2 GO:0031667| response to nutrient levels SOD1;SRC;GSTP1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;PRKCB;PPP2CA;ABL1;SEC14L2 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8 GO:0042493| response to drug SOD1;LYN;ABCB1;SRC GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0002250| adaptive immune response LYN;PRKCB GO:0038128| PRKCA;SRC GO:0006816| calcium ion transport PRKCB;CAMK2G GO:0051602| response to electrical stimulus NQO1;SRC GO:0006954| inflammatory response LYN;ALOX5;HCK GO:0090330| regulation of platelet aggregation PRKCA;LYN 5274:[DB06616 DB08190] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;NQO2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;NQO2 5275:[DB06616 DB08221] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways GO:0051894| positive regulation of focal adhesion assembly TEK;ABL1 GO:0051259| protein oligomerization CAMK2G;TEK GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;BCR;MAP2K2;TEK;SRC;MAP2K1;HCK GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;TEK GO:0043066| negative regulation of apoptotic process HCK;SRC;TEK GO:0007507| heart development TEK;MAP2K1 GO:0050900| leukocyte migration SRC;TEK;LYN GO:0043114| regulation of vascular permeability SRC;TEK;BCR GO:0001934| positive regulation of protein phosphorylation TEK;ABL1;LYN GO:2000251| positive regulation of actin cytoskeleton reorganization TEK;HCK;ABL1 GO:0050728| negative regulation of inflammatory response TEK;BCR GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC;TEK GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2;TEK GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TEK GO:0010595| positive regulation of endothelial cell migration ABL1;TEK GO:0016310| phosphorylation MAP2K2;BCR;SRC;TEK;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;TEK;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway TEK;HCK;LYN GO:0043434| response to peptide hormone stimulus LYN;TEK GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;TEK;MAP2K2;BCR;CDK2;LYN;CAMK2G;MAP3K2 GO:0007165| signal transduction LYN;BCR;SRC;TEK;MAP2K1 GO:1902533| SRC;TEK GO:2000352| negative regulation of endothelial cell apoptosis ABL1;TEK GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;TEK;SRC;MAP2K1 GO:0046777| protein autophosphorylation CAMK2G;LYN;SRC;TEK;BCR;HCK;ABL1 GO:0010033| response to organic substance TEK;CDK2 GO:0060216| definitive hemopoiesis TEK;BCR 5276:[DB06616 DB00633] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;LYN GO:0009636| response to toxin CYP1A1;LYN GO:0008283| cell proliferation SRC;CYP1A1 GO:0010033| response to organic substance CYP1A2;CDK2;CYP1A1 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0030168| platelet activation ADRA2A;SRC;LYN GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4 GO:0007165| signal transduction LYN;ADRA2A;MAP2K1;BCR;SRC GO:0097267| CYP2C8;CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP2E1;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2E1;CYP1A2;CYP2D6;CYP2C8 GO:0042493| response to drug ABCB1;SRC;CYP1A2;CYP2E1;CYP1A1;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0032148| activation of protein kinase B activity SRC;ADRA2A GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1;CYP2E1;CYP1A2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;ADRA2A GO:0009615| response to virus SRC;CYP1A1 5277:[DB06616 DB04578] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion ABL1;HCK;SRC;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK GO:0031295| T cell costimulation SRC;DPP4;LYN 5278:[DB06616 DB01349] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes CYP3A4 common pathways GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;AGTR2;MAP3K2 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0008284| positive regulation of cell proliferation CDK2;LYN;AGTR2;HCK GO:0050727| regulation of inflammatory response HCK;AGTR1;LYN GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0035556| intracellular signal transduction CAMK2G;LYN;AGTR2;SRC;BCR GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042127| regulation of cell proliferation AGTR1;ABL1;SRC GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006954| inflammatory response HCK;AGTR2;LYN GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent AGTR2;MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0007420| brain development AGTR2;BCR GO:0007165| signal transduction AGTR2;AGTR1;BCR;SRC;MAP2K1;LYN GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0050715| positive regulation of cytokine secretion SRC;AGTR2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AGTR1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 5279:[DB06616 DB11774] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0042493| response to drug LYN;CYP1A2;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 5280:[DB06616 DB04910] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04910|Oxibendazole TUBB4B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB4B;CDK2;ABCB1 GO:0006928| cellular component movement TUBB4B;MAP2K1 GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB4B;CDK2 5281:[DB06616 DB08772] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;AKR1B1 GO:0055114| oxidation-reduction process AKR1B10;AKR1B1;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process AKR1B10;CYP3A4;CYP2C8 GO:0010033| response to organic substance CDK2;AKR1B1 5282:[DB06616 DB08222] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways GO:0006629| lipid metabolic process CLPS;CYP3A4;PNLIP 5283:[DB06616 DB01951] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01951|Gpi-1046 FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway HCK;FKBP1A GO:0001933| negative regulation of protein phosphorylation FKBP1A;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;SRC 5284:[DB06616 DB00140] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;BLVRB;MAOA;MTHFR GO:0042493| response to drug MTHFR;LYN;SRC;ABCB1 GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;RFK;MAP3K2;CAMK2G;CDK2;LYN GO:0070555| response to interleukin-1 MTHFR;SRC GO:0006915| apoptotic process RFK;ABL1 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0043200| response to amino acid stimulus LYN;MTHFR 5285:[DB06616 DB01231] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CHRM1;CDK2;LYN GO:0009615| response to virus CHRM2;SRC GO:0007399| nervous system development CHRM2;CHRM1;CAMK2G;CHRM3 GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0008283| cell proliferation CHRM3;CHRM1;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRM1;LYN;CHRM2;CHRM3 5286:[DB06616 DB00710] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00710|Ibandronate FDPS common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C8 GO:0016032| viral reproduction LYN;SRC;FDPS;HCK GO:0006629| lipid metabolic process CYP3A4;FDPS 5287:[DB06616 DB00144] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0007411| axon guidance PRKCA;SRC GO:0007049| cell cycle SRC;SMPD3;CDK2 GO:0010033| response to organic substance DGKD;CDK2 GO:0070374| positive regulation of ERK1 and ERK2 cascade PRKCA;ABL1;MAP2K2;SRC;MAP2K1 GO:0045785| positive regulation of cell adhesion PRKCA;SRC GO:0006915| apoptotic process ABL1;PRKCA GO:0007165| signal transduction DGKD;DGKG;LYN;SRC;BCR;MAP2K1 GO:0070555| response to interleukin-1 SRC;PRKCA GO:0016310| phosphorylation LYN;CDK2;DGKG;CAMK2G;MAP3K2;DGKD;PRKCA;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0050764| regulation of phagocytosis HCK;SCARB1 GO:0010595| positive regulation of endothelial cell migration SCARB1;PRKCA;ABL1 GO:0030335| positive regulation of cell migration PRKCA;ATP8A1;LYN GO:0045332| phospholipid translocation ATP8A1;ABCB1 GO:0006468| protein phosphorylation PRKCA;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0030168| platelet activation SRC;PRKCA;DGKD;LYN;DGKG GO:0090330| regulation of platelet aggregation LYN;PRKCA GO:0016032| viral reproduction HCK;SRC;SCARB1;LYN GO:0038128| SRC;PRKCA GO:0007173| epidermal growth factor receptor signaling pathway DGKD;ABL1;SRC GO:0018105| peptidyl-serine phosphorylation PRKCA;SRC;CDK2;CAMK2G GO:0031663| lipopolysaccharide-mediated signaling pathway SCARB1;LYN;HCK GO:0006897| endocytosis DGKD;ABL1 GO:0035556| intracellular signal transduction BCR;SRC;PRKCA;DGKD;LYN;DGKG;CAMK2G GO:0007155| cell adhesion PRKCA;ABL1;HCK;SRC GO:0006629| lipid metabolic process PISD;SMPD3;PTDSS2;PTDSS1;CYP3A4 GO:0045931| positive regulation of mitotic cell cycle PRKCA;ABL1 GO:0007275| multicellular organismal development SMPD3;DGKD;CDK2;CAMK2G 5288:[DB06616 DB00511] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 GO:0042493| response to drug ABCB1;SRC;ATP1A1;LYN GO:0006813| potassium ion transport CDK2;ATP1A1 5289:[DB06616 DB00917] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0070371| ERK1 and ERK2 cascade PTGER4;MAP2K2;MAP2K1 GO:0050728| negative regulation of inflammatory response BCR;PTGER4 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0055114| oxidation-reduction process ABCC4;CYP2C8;CYP11A1;CYP3A4;CYP19A1 GO:0042493| response to drug ABCC4;ABCB1;SRC;LYN GO:0006629| lipid metabolic process CYP3A4;CYP11A1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGER4 GO:0002576| platelet degranulation LYN;ABCC4 GO:0006935| chemotaxis PTGDR2;MAP2K1 GO:0060065| uterus development SRC;CYP19A1 GO:0009612| response to mechanical stimulus SRC;PTGER4 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGER2 GO:0032496| response to lipopolysaccharide PTGER2;BCR;PTGER1;PTGER4 GO:0010033| response to organic substance CDK2;ABCC4 GO:0042359| vitamin D metabolic process CYP11A1;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0055085| transmembrane transport SLCO4A1;SLC22A7;SLCO2B1;SLC22A11;ABCC5;SLC51B;SLC22A2;ABCB1;ABCC4;SLCO1B1;SLC51A;SLC22A8;SLC22A6;SLCO3A1;SLCO1C1;SLCO1A2;SLCO2A1 GO:0014070| response to organic cyclic compound ABCC4;LYN GO:0009636| response to toxin LYN;SLC22A8 GO:0007165| signal transduction MAP2K1;BCR;PTGER2;SRC;PTGDR2;PTGER3;PTGER4;PTGER1;LYN GO:0050715| positive regulation of cytokine secretion SRC;PTGER4 GO:0006810| transport ABCC5;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP11A1 5290:[DB06616 DB00331] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;PRKAB1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0007050| cell cycle arrest ABL1;PRKAB1;MAP2K1 GO:0007165| signal transduction MAP2K1;SRC;BCR;PRKAB1;LYN GO:0055085| transmembrane transport SLC29A4;SLC22A1;SLC22A3;SLC22A2;SLC47A2;ABCB1;SLC47A1 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;SLC47A2;SLC22A2;SLC47A1;ABCB1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;PRKAB1 GO:1901796| PRKAB1;CDK2 GO:0006629| lipid metabolic process PRKAB1;CYP3A4 GO:0016236| macroautophagy SRC;PRKAB1 5291:[DB06616 DB08353] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08353|2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0007049| cell cycle SRC;CSNK2A1;CDK2 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CSNK2A1 GO:0007165| signal transduction CSNK2A1;LYN;BCR;SRC;MAP2K1 GO:0016310| phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;CSNK2A1;MAP3K2 GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2;CSNK2A1 GO:0016236| macroautophagy SRC;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CSNK2A1 5292:[DB06616 DB03292] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways GO:0009612| response to mechanical stimulus SRC;PSPH GO:0031667| response to nutrient levels PSPH;SRC 5293:[DB06616 DB07700] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;AKR1C3;CYP3A4 GO:0030216| keratinocyte differentiation MAP2K1;AKR1C3 GO:0034614| cellular response to reactive oxygen species AKR1C3;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;AKR1C3;HCK GO:0055114| oxidation-reduction process CYP3A4;AKR1C3;CYP2C8 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;AKR1C3 5294:[DB06616 DB01271] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01271|Idursulfase PLIN3 common genes common pathways 5295:[DB06616 DB07680] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07680|[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID CMA1 common genes common pathways GO:0050727| regulation of inflammatory response LYN;HCK;CMA1 5296:[DB06616 DB04957] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;CYP1A1;LYN GO:0008209| androgen metabolic process CYP3A4 GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP3A4;CYP1A1 GO:0009615| response to virus SRC;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP3A5 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A1;BCR GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0010033| response to organic substance CDK2;CYP1A1 GO:0008283| cell proliferation CYP1A1;SRC GO:0002933| CYP2C8;CYP3A5;CYP1A1;CYP3A4 GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0009636| response to toxin CYP1A1;LYN GO:0055085| transmembrane transport ABCB1;KCNQ1;KCNH2 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 GO:0006813| potassium ion transport KCNQ1;KCNE1;KCNH2;CDK2 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP2C8;CYP1A1;CYP3A4 GO:0072358| cardiovascular system development KCNQ1;ABL1 GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2C8;CYP3A5 5297:[DB06616 DB04919] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04919|Alfimeprase FGA;FGB common genes common pathways GO:0045087| innate immune response HCK;FGA;FGB;SRC;ABL1;LYN GO:0002576| platelet degranulation FGA;FGB;LYN GO:0002250| adaptive immune response FGA;FGB;LYN GO:0007165| signal transduction LYN;FGA;MAP2K1;FGB;SRC;BCR GO:1900026| ABL1;FGB;FGA GO:0002376| immune system process LYN;FGA;HCK;SRC;FGB GO:0030168| platelet activation FGB;SRC;FGA;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;FGB;MAP2K2;FGA;MAP2K1;ABL1 GO:0007596| blood coagulation LYN;FGA;FGB GO:2000352| negative regulation of endothelial cell apoptosis ABL1;FGB;FGA 5298:[DB06616 DB13203] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug SRC;ABCB1;CYP1A2;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 5299:[DB06616 DB06479] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0007165| signal transduction LYN;PDE4A;MAP2K1;BCR;SRC GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 5300:[DB06616 DB08885] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;VEGFB;VEGFA;PGF GO:0051272| positive regulation of cellular component movement LYN;VEGFA GO:0043066| negative regulation of apoptotic process VEGFA;SRC;VEGFB;HCK GO:0042327| positive regulation of phosphorylation VEGFA;LYN GO:0008284| positive regulation of cell proliferation VEGFA;PGF;CDK2;LYN;HCK GO:0002576| platelet degranulation VEGFB;VEGFA;LYN GO:0007399| nervous system development VEGFA;CAMK2G GO:0007507| heart development MAP2K1;VEGFB GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VEGFA GO:0008360| regulation of cell shape VEGFA;HCK GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;VEGFA GO:0007498| mesoderm development VEGFA;HCK GO:0007275| multicellular organismal development VEGFA;CAMK2G;PGF;CDK2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;VEGFB GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFB;SRC;ABL1;VEGFA;LYN GO:0031954| positive regulation of protein autophosphorylation SRC;VEGFA GO:0010629| negative regulation of gene expression VEGFB;MAP2K1;MAP2K2;VEGFA GO:0042493| response to drug ABCB1;SRC;VEGFB;PGF;LYN GO:0001934| positive regulation of protein phosphorylation VEGFA;LYN;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;PGF GO:0030335| positive regulation of cell migration VEGFA;LYN GO:0010595| positive regulation of endothelial cell migration ABL1;VEGFA GO:0071456| cellular response to hypoxia VEGFA;SRC GO:0030154| cell differentiation VEGFA;PGF;CAMK2G;HCK GO:0010628| positive regulation of gene expression MAP2K1;SRC;VEGFA GO:0043406| positive regulation of MAP kinase activity VEGFA;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade VEGFA;SRC;MAP2K2;VEGFB;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion VEGFA;SRC 5301:[DB06616 DB03832] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CROT 5302:[DB06616 DB02353] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways GO:0014911| positive regulation of smooth muscle cell migration CCL5;SRC GO:0045785| positive regulation of cell adhesion SRC;CCL5 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;CCL5 GO:0009636| response to toxin CCL5;LYN GO:0006887| exocytosis HCK;CCL5 GO:0030335| positive regulation of cell migration LYN;CCL5 GO:0043547| positive regulation of GTPase activity BCR;CCL5 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CCL5;CAMK2G GO:0006816| calcium ion transport CCL5;CAMK2G GO:0006954| inflammatory response CCL5;LYN;HCK GO:0042327| positive regulation of phosphorylation LYN;CCL5 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN;CCL5 GO:0006935| chemotaxis MAP2K1;CCL5 GO:0009615| response to virus CCL5;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein CCL5;LYN 5303:[DB06616 DB11760] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0034599| cellular response to oxidative stress ABL1;PARP1 GO:1901529| ABCB1 GO:0006281| DNA repair ABL1;PARP1;PARP2;CDK2 GO:0006974| response to DNA damage stimulus PARP1;LYN;CDK2;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901216| PARP1;ABL1 GO:0042493| response to drug ABCG2;ABCB1;SRC;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;PARP1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0032869| cellular response to insulin stimulus PARP1;SRC GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:1900182| SRC;PARP1 GO:0006915| apoptotic process ABL1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;PARP1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0055085| transmembrane transport ABCG2;ABCB1 5304:[DB06616 DB08750] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR 5305:[DB06616 DB02691] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FABP6 GO:0008285| negative regulation of cell proliferation FABP6;LYN;MAP2K1 GO:0055085| transmembrane transport ABCB1;SLCO1B1;SLCO1B3;SLCO1A2 5306:[DB06616 DB01889] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01889|16,17-Androstene-3-Ol NR1I3 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I3;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;NR1I3 5307:[DB06616 DB00614] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00614|Furazolidone MAOB;MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOB;MAOA;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;MAOB;LYN GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0009636| response to toxin MAOB;LYN 5308:[DB06616 DB01733] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01733|L-Phospholactate PKM common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PKM GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;PKM;ABL1 GO:0010033| response to organic substance CDK2;PKM GO:0032868| response to insulin stimulus PKM;LYN 5309:[DB06616 DB01399] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006954| inflammatory response PTGS1;HCK;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC;ABL1 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0070542| response to fatty acid PTGS2;SRC 5310:[DB06616 DB05514] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05514|Cobiprostone CLCN2 common genes common pathways GO:0006810| transport ABCB1;CLCN2 GO:0055085| transmembrane transport CLCN2;ABCB1 5311:[DB06616 DB07831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes ABL1 common pathways GO:1904531| ABL1 GO:1901216| ABL1 GO:0006909| phagocytosis ABL1;HCK GO:0010506| regulation of autophagy ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0038083| LYN;ABL1;SRC;HCK GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:1900042| ABL1 GO:0000278| mitotic cell cycle ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0006914| autophagy ABL1 GO:0050885| neuromuscular process controlling balance ABL1;BCR GO:0042770| signal transduction in response to DNA damage ABL1 GO:0006298| mismatch repair ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1 GO:1902036| ABL1 GO:0038096| HCK;SRC;ABL1;LYN GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0030036| actin cytoskeleton organization BCR;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0038189| ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0030516| regulation of axon extension ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:1905244| ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0043542| endothelial cell migration ABL1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:0006897| endocytosis ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:2000145| regulation of cell motility ABL1 GO:1900275| ABL1 GO:0030155| regulation of cell adhesion ABL1 GO:0030035| microspike assembly ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:1904528| ABL1 GO:0006281| DNA repair ABL1;CDK2 GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2 GO:0051882| mitochondrial depolarization ABL1 GO:0045087| innate immune response HCK;SRC;ABL1;LYN GO:0007155| cell adhesion ABL1;SRC;HCK GO:0048668| collateral sprouting ABL1 GO:2000772| regulation of cellular senescence ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;LYN GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0030182| neuron differentiation MAP2K1;ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:0006915| apoptotic process ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0045580| regulation of T cell differentiation ABL1 GO:0002322| B cell proliferation involved in immune response ABL1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0042100| B cell proliferation ABL1 GO:0045184| establishment of protein localization ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0001922| B-1 B cell homeostasis ABL1 GO:0050853| B cell receptor signaling pathway LYN;ABL1 GO:0009791| post-embryonic development ABL1 GO:1900272| ABL1 GO:1990051| ABL1 GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN GO:0046632| alpha-beta T cell differentiation ABL1 GO:0006464| protein modification process ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0072358| cardiovascular system development ABL1 GO:1903053| ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0030100| regulation of endocytosis ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0001843| neural tube closure ABL1 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:1900026| ABL1 GO:0006979| response to oxidative stress ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0048536| spleen development ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0048538| thymus development ABL1;MAP2K1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:1905555| ABL1 GO:1903351| ABL1 GO:0090135| actin filament branching ABL1 GO:0007050| cell cycle arrest MAP2K1;ABL1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:1902715| ABL1 5312:[DB06616 DB07093] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07093|{3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC GO:0010033| response to organic substance AKR1B1;CDK2 5313:[DB06616 DB01272] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01272|Alglucosidase alfa M6PR common genes common pathways GO:0007165| signal transduction M6PR;LYN;MAP2K1;SRC;BCR 5314:[DB06616 DB07446] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07446|N-(biphenyl-4-ylsulfonyl)-D-leucine MMP12 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;MMP12 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;CDK2 5315:[DB06616 DB07396] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways 5316:[DB06616 DB05796] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05796|Daglutril MME common genes common pathways 5317:[DB06616 DB09140] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0006979| response to oxidative stress MT-CO1;ABL1 GO:0007165| signal transduction LYN;SRC;BCR;NOX1;MAP2K1 GO:0016477| cell migration SRC;NOX1 GO:0007596| blood coagulation HBB;LYN GO:0042542| response to hydrogen peroxide SRC;HBB;HBA1 GO:0008284| positive regulation of cell proliferation HCK;NOX1;LYN;CDK2 GO:0051602| response to electrical stimulus SRC;MT-CO1 GO:0006954| inflammatory response LYN;NOX1;HCK GO:0055114| oxidation-reduction process MT-CO1;CYP3A4;NOX1;CYP2C8 5318:[DB06616 DB01237] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01237|Bromodiphenhydramine HRH1;SLC22A6 common genes common pathways GO:0006954| inflammatory response LYN;HRH1;HCK GO:0043114| regulation of vascular permeability HRH1;SRC;BCR GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;HRH1 5319:[DB06616 DB08259] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4;EPHX2 GO:0009636| response to toxin LYN;EPHX2 GO:0010628| positive regulation of gene expression SRC;MAP2K1;EPHX2 GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0006954| inflammatory response EPHX2;LYN;HCK 5320:[DB06616 DB01738] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01738|Phosphorylcolamine PRKCB common genes common pathways GO:0006915| apoptotic process PRKCB;ABL1 GO:0050853| B cell receptor signaling pathway LYN;PRKCB;ABL1 GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;PRKCB;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0030168| platelet activation LYN;PRKCB;SRC GO:0016310| phosphorylation ABL1;SRC;PRKCB;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0007165| signal transduction PRKCB;SRC;BCR;MAP2K1;LYN GO:0002376| immune system process HCK;PRKCB;SRC;LYN GO:0050861| positive regulation of B cell receptor signaling pathway LYN;PRKCB GO:0006355| regulation of transcription, DNA-dependent ABL1;PRKCB GO:0002250| adaptive immune response LYN;PRKCB GO:0006816| calcium ion transport CAMK2G;PRKCB GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PRKCB;ABL1 GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;PRKCB;SRC GO:0035556| intracellular signal transduction PRKCB;SRC;BCR;LYN;CAMK2G 5321:[DB06616 DB03978] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03978|Tyrosinal tyrS;YARS;YARS common genes common pathways GO:0006915| apoptotic process ABL1;YARS GO:0007165| signal transduction LYN;MAP2K1;YARS;BCR;SRC 5322:[DB06616 DB06814] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06814|Protokylol ADRB2 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;ADRB2;LYN GO:0045453| bone resorption SRC;ADRB2 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 5323:[DB06616 DB07919] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA 5324:[DB06616 DB03945] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1;CRP GO:0006954| inflammatory response HCK;CRP;LYN 5325:[DB06616 DB09064] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09064|Ciprofibrate PPARA common genes common pathways GO:0032868| response to insulin stimulus LYN;PPARA GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;PPARA;CDK2 GO:0006355| regulation of transcription, DNA-dependent PPARA;ABL1 GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0006629| lipid metabolic process PPARA;CYP3A4 GO:0007507| heart development PPARA;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;CDK2 5326:[DB06616 DB03451] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;VDR;SRC GO:0008285| negative regulation of cell proliferation LYN;VDR;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;VDR;LYN GO:0006355| regulation of transcription, DNA-dependent VDR;ABL1 GO:0006816| calcium ion transport VDR;CAMK2G GO:0007275| multicellular organismal development CDK2;CAMK2G;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VDR 5327:[DB06616 DB12118] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12118|Sotatercept ACVR2A common genes common pathways GO:0007498| mesoderm development ACVR2A;HCK GO:0001934| positive regulation of protein phosphorylation LYN;ACVR2A;ABL1 GO:0023014| signal transduction via phosphorylation event ACVR2A;LYN GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;ACVR2A;LYN;CDK2;CAMK2G GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;CDK2;LYN;CAMK2G;ACVR2A;MAP3K2 5328:[DB06616 DB02039] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent KAT5;SRC GO:0006260| DNA replication KAT5;CDK2 GO:0016032| viral reproduction KAT5;LYN;SRC;HCK GO:0006355| regulation of transcription, DNA-dependent KAT5;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;KAT5;CDK2;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;KAT5 GO:1901796| KAT5;CDK2 5329:[DB06616 DB05234] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05234|LGD2941 AR common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;AR;LYN GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;AR GO:0042327| positive regulation of phosphorylation LYN;AR GO:0051259| protein oligomerization CAMK2G;AR GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;SRC;MAP2K2;AR 5330:[DB06616 DB05542] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05542|Naronapride HTR4 common genes common pathways GO:0007165| signal transduction LYN;HTR4;MAP2K1;BCR;SRC 5331:[DB06616 DB04757] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug ABCB1;SRC;PNP;LYN 5332:[DB06616 DB03435] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways GO:0016310| phosphorylation MAP3K2;CMPK1;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 5333:[DB06616 DB04244] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04244|(2R)-2-(3-Biphenylyl)-N-{(2R)-2-hydroxy-3-[(2-pyridinylsulfonyl)amino]propyl}-4-methylpentanamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 5334:[DB06616 DB02267] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02267|Argininosuccinate ASL;argG common genes common pathways 5335:[DB06616 DB08159] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways GO:0016310| phosphorylation TOP1;MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0016032| viral reproduction TOP1;LYN;SRC;HCK GO:0006260| DNA replication TOP1;CDK2 GO:0042493| response to drug SRC;ABCB1;LYN;TOP1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;TOP1;SRC 5336:[DB06616 DB08101] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5337:[DB06616 DB12688] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways GO:0042493| response to drug EEF2;SRC;ABCB1;LYN GO:0007155| cell adhesion CD22;HCK;SRC;ABL1 GO:0042542| response to hydrogen peroxide EEF2;SRC 5338:[DB06616 DB02282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 5339:[DB06616 DB06039] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06039|PA-1050040 gag common genes common pathways 5340:[DB06616 DB02311] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;SRC GO:0019221| cytokine-mediated signaling pathway HCK;FKBP1A GO:0001933| negative regulation of protein phosphorylation LYN;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;ABL1 5341:[DB06616 DB04069] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways GO:0046777| protein autophosphorylation CAMK2G;DAPK1;LYN;BCR;SRC;HCK;ABL1 GO:0006915| apoptotic process ABL1;DAPK1 GO:0007165| signal transduction MAP2K1;BCR;SRC;DAPK1;LYN GO:0006468| protein phosphorylation LYN;CDK2;DAPK1;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0016310| phosphorylation CDK2;LYN;DAPK1;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0010506| regulation of autophagy ABL1;DAPK1 GO:0042981| regulation of apoptotic process MAP3K2;DAPK1;MAP2K2;MAP2K1 GO:0043066| negative regulation of apoptotic process DAPK1;SRC;HCK GO:0035556| intracellular signal transduction SRC;BCR;LYN;DAPK1;CAMK2G 5342:[DB06616 DB00178] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0007165| signal transduction LYN;BDKRB1;MAP2K1;SRC;BCR GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;BDKRB1 GO:0007204| elevation of cytosolic calcium ion concentration BDKRB1;ABL1 GO:0006810| transport ABCB1;SLC15A2;SLC15A1 GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0016477| cell migration BDKRB1;SRC GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 GO:0009612| response to mechanical stimulus SRC;BDKRB1 GO:0032496| response to lipopolysaccharide BCR;BDKRB1 GO:0001933| negative regulation of protein phosphorylation LYN;BDKRB1 GO:0006954| inflammatory response BDKRB1;LYN;HCK GO:0042493| response to drug ABCB1;SRC;BCHE;LYN 5343:[DB06616 DB00592] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction GABRB3;MAP2K1;BCR;SRC;LYN GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006810| transport GABRB3;ABCB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 5344:[DB06616 DB01160] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGFR;HCK GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGFR GO:0032496| response to lipopolysaccharide BCR;PTGFR;PTGIR GO:0010628| positive regulation of gene expression MAP2K1;PTGFR;SRC GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0055085| transmembrane transport SLCO2A1;SLCO3A1;SLC22A6;SLC22A8;ABCB1;SLC22A2;SLC22A11;SLC22A7 GO:0009636| response to toxin SLC22A8;LYN GO:0007165| signal transduction LYN;PTGIR;BCR;PTGFR;SRC;MAP2K1 GO:0065009| regulation of molecular function CAMK2G;PTGIR 5345:[DB06616 DB13996] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0042493| response to drug ABCB1;SRC;ATP1A1;LYN GO:0006813| potassium ion transport ATP1A1;CDK2 5346:[DB06616 DB09571] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09571|Levmetamfetamine PNMT common genes common pathways 5347:[DB06616 DB00815] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00815|Sodium lauryl sulfate ALB common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0002576| platelet degranulation ALB;LYN 5348:[DB06616 DB00839] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00839|Tolazamide ABCC8;KCNJ11;CYP2C9 common genes common pathways GO:0055085| transmembrane transport KCNJ11;ABCC8;ABCB1 GO:0032868| response to insulin stimulus LYN;ABCC8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0006813| potassium ion transport ABCC8;CDK2;KCNJ11 GO:0007165| signal transduction BCR;SRC;MAP2K1;ABCC8;LYN GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0042493| response to drug LYN;ABCC8;KCNJ11;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide BCR;ABCC8 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 5349:[DB06616 DB03253] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;LYN;DPP4 GO:0007155| cell adhesion HCK;SRC;ABL1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CDK2;LYN;HCK GO:0043542| endothelial cell migration ABL1;DPP4 5350:[DB06616 DB00925] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0042493| response to drug LYN;SRC;ADRA1A;ABCB1 GO:0000165| MAPKKK cascade CALM1;MAP2K2;MAP2K1;CAMK2G GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0007275| multicellular organismal development ADRA1B;CAMK2G;CDK2;ADRA1D GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;ADRA1A;SRC;ADRA1B GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA1D;ADRA2A;HCK GO:0002576| platelet degranulation LYN;CALM1 GO:0032148| activation of protein kinase B activity ADRA2B;ADRA2C;SRC;ADRA2A GO:0008283| cell proliferation ADRA1B;SRC;ADRA1D GO:0038095| LYN;CALM1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;ADRA1A;SRC GO:0055085| transmembrane transport ABCB1;SLC22A2;CALM1;SLC22A1;SLC22A3 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A3;SLC22A1 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;CALM1;ADRB2 GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0030168| platelet activation ADRA2A;SRC;LYN;ADRA2B;ADRA2C GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1B;ABL1;ADRA1A GO:0045453| bone resorption ADRB2;SRC GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction SRC;ADRA1A;BCR;MAP2K1;ADRA2A;ADRA1B;ADRA1D;ADRA2C;LYN;ADRA2B;ADRB2 5351:[DB06616 DB12418] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12418|Saccharin CA3 common genes common pathways GO:0006979| response to oxidative stress CA3;ABL1 5352:[DB06616 DB08162] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08162|Fasudil PKIA;PRKACA;ROCK1;ROCK2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;ROCK2 GO:0050900| leukocyte migration ROCK1;SRC;LYN GO:0010506| regulation of autophagy ABL1;ROCK1 GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2;PKIA GO:0030036| actin cytoskeleton organization BCR;ROCK1;ABL1;ROCK2 GO:0043393| regulation of protein binding PRKACA;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PRKACA;SRC GO:0051894| positive regulation of focal adhesion assembly ABL1;ROCK1 GO:0051298| centrosome duplication CDK2;ROCK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PKIA;CDK2 GO:0030155| regulation of cell adhesion ROCK1;ABL1;ROCK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway ROCK2;ROCK1;SRC GO:0035556| intracellular signal transduction LYN;ROCK2;CAMK2G;ROCK1;SRC;BCR GO:2000145| regulation of cell motility ROCK1;ABL1;ROCK2 GO:0018105| peptidyl-serine phosphorylation CAMK2G;PRKACA;CDK2;SRC GO:0006915| apoptotic process ABL1;ROCK1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;PRKACA GO:0007596| blood coagulation PRKACA;LYN GO:0031175| neuron projection development ROCK1;LYN GO:0048013| ephrin receptor signaling pathway LYN;ROCK2;ROCK1;SRC GO:0010628| positive regulation of gene expression ROCK1;SRC;MAP2K1;ROCK2 GO:0006468| protein phosphorylation CAMK2G;ROCK2;CDK2;LYN;PRKACA;MAP3K2;ROCK1;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0034605| cellular response to heat LYN;PRKACA GO:0016310| phosphorylation ABL1;ROCK1;SRC;MAP2K2;BCR;HCK;MAP2K1;ROCK2;CAMK2G;PRKACA;CDK2;LYN;MAP3K2 GO:0010595| positive regulation of endothelial cell migration ROCK2;ABL1 GO:0007165| signal transduction SRC;BCR;MAP2K1;ROCK1;LYN GO:0032956| regulation of actin cytoskeleton organization ROCK2;ABL1;ROCK1 5353:[DB06616 DB07837] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways GO:0042127| regulation of cell proliferation SGK1;SRC;ABL1 GO:0035556| intracellular signal transduction SRC;BCR;SGK1;LYN;CAMK2G GO:0018105| peptidyl-serine phosphorylation SGK1;SRC;CDK2;CAMK2G GO:0006974| response to DNA damage stimulus SGK1;ABL1;LYN;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;SGK1;MAP2K2 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;SGK1;LYN;CDK2;CAMK2G;MAP3K2 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;SGK1;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;SGK1 GO:0006915| apoptotic process ABL1;SGK1 5354:[DB06616 DB01811] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways GO:0045087| innate immune response HCK;SRC;LTF;ABL1;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;LTF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;LTF GO:0001817| regulation of cytokine production LYN;LTF GO:0006355| regulation of transcription, DNA-dependent LTF;ABL1 GO:0002376| immune system process LYN;HCK;SRC;LTF GO:0071902| positive regulation of protein serine/threonine kinase activity LTF;MAP2K1;SRC;MAP2K2 GO:0033690| positive regulation of osteoblast proliferation LTF;ABL1 5355:[DB06616 DB00449] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0030168| platelet activation LYN;SRC;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction LYN;ADRB2;BCR;SRC;ADRA1A;MAP2K1;ADRA2A GO:0045453| bone resorption ADRB2;SRC GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;ADRA1A;MAP2K2;ABL1 GO:0008283| cell proliferation ACHE;SRC GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN;BCHE GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0032148| activation of protein kinase B activity SRC;ADRA2A GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;ADRA1A;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA2A;HCK GO:0042493| response to drug BCHE;LYN;ABCB1;SRC;ADRA1A GO:0006260| DNA replication CDK2;ACHE GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR 5356:[DB06616 DB12061] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0042493| response to drug ABCB1;DRD2;SRC;LYN;DRD3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DRD3;HTR1A GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;DRD2;SRC GO:0048678| response to axon injury LYN;DRD2 GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;DRD2;MAP2K2;MAP2K1;ABL1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;DRD4;MAP3K2 GO:0008283| cell proliferation HTR1A;SRC GO:0009636| response to toxin LYN;DRD2 GO:0007165| signal transduction LYN;DRD3;DRD4;HTR1A;MAP2K1;BCR;DRD2;SRC GO:0030900| forebrain development DRD2;SRC 5357:[DB06616 DB06215] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0055114| oxidation-reduction process FTH1;CYP2C8;CYP3A4 GO:0002576| platelet degranulation LYN;TF GO:0008285| negative regulation of cell proliferation MAP2K1;FTH1;LYN 5358:[DB06616 DB01444] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes common pathways GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;OPRD1 GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;LYN;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;SRC 5359:[DB06616 DB09167] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0006954| inflammatory response HRH1;LYN;HCK GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0042493| response to drug SLC6A4;SRC;ADRA1A;ABCB1;LYN;HTR2A;CYP1A2;SLC6A2 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP1A2;CYP2C9;CYP3A4 GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0008284| positive regulation of cell proliferation HTR1A;CHRM1;HTR2A;LYN;CDK2;ADRA1D;ADRA2A;HCK GO:0009615| response to virus SRC;CHRM2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C8;CYP2C19;CYP2D6 GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;ADRA1A;BCR;ADRA1B GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP2C8;CYP2C19 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;ADRA2A;SRC GO:0007399| nervous system development CHRM3;CHRM1;CAMK2G;CHRM2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C19;CYP2D6 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0042737| drug catabolic process CYP2D6;CYP1A2;CYP3A4;CYP2C9 GO:0007275| multicellular organismal development CAMK2G;CDK2;ADRA1D;ADRA1B GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A;HTR2A GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance SLC6A4;CDK2;CYP1A2 GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;LYN GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0008283| cell proliferation CHRM3;CHRM5;ADRA1D;HTR1A;CHRM1;CHRM4;SRC;ADRA1B GO:0009636| response to toxin LYN;SLC6A4 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K1;MAP2K2;SRC;ADRA1A;ABL1 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;ADRA2B GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP1A2;CYP2C9;CYP3A4 GO:0007165| signal transduction ADRA1B;ADRA2A;MAP2K1;CHRM4;BCR;ADRA1A;SRC;ADRA2B;LYN;HTR2A;CHRM2;HTR1A;CHRM1;ADRA2C;HRH1;CHRM3;ADRA1D;CHRM5 GO:0007420| brain development BCR;SLC6A4 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2D6;CYP1A2;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP1A2;CYP2C8;CYP2C19 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP1A2;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ADRA1D;ADRA1B;ABL1;ADRA1A GO:0030168| platelet activation ADRA2C;LYN;ADRA2B;ADRA2A;SRC GO:0006810| transport SLC6A2;ABCB1 5360:[DB06616 DB05417] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05417|GW 468816 GLRA1 common genes common pathways 5361:[DB06616 DB02338] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0007165| signal transduction TXNRD1;MAP2K1;SRC;BCR;LYN GO:0008283| cell proliferation SRC;TXNRD1 GO:0034599| cellular response to oxidative stress ABL1;TXNRD1 GO:0055114| oxidation-reduction process CYP3A4;AASS;CYP2C8;TXNRD1;DPYD 5362:[DB06616 DB01973] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways GO:0045785| positive regulation of cell adhesion PRSS2;SRC 5363:[DB06616 DB00373] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2D6;CYP3A4 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007165| signal transduction BCR;ADRB1;SRC;MAP2K1;LYN;ADRB2 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4 GO:0045453| bone resorption ADRB2;SRC GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0099040| ABCB1 GO:0042493| response to drug LYN;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP2C19;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 5364:[DB06616 DB02508] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C8 GO:0016032| viral reproduction SRC;HCK;FDPS;LYN GO:0006629| lipid metabolic process CYP3A4;FDPS 5365:[DB06616 DB00319] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 5366:[DB06616 DB02473] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02473|6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0042127| regulation of cell proliferation SRC;PLAU;ABL1 GO:0006935| chemotaxis PLAU;MAP2K1 GO:0030335| positive regulation of cell migration LYN;PLAU GO:0007165| signal transduction LYN;PLAU;SRC;BCR;MAP2K1 GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0007596| blood coagulation PLAU;LYN 5367:[DB06616 DB07664] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07664|5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE CSNK1G3;SLK;CAMK4;CLK3;ABL2 common genes common pathways GO:0030100| regulation of endocytosis ABL2;ABL1 GO:0016310| phosphorylation SLK;MAP3K2;CAMK2G;LYN;CDK2;ABL2;BCR;MAP2K2;SRC;MAP2K1;HCK;CSNK1G3;ABL1;CLK3;CAMK4 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway ABL2;LYN;HCK GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ABL2 GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;CLK3;CAMK4;CSNK1G3;ABL1;MAP3K2;SLK;CDK2;LYN;ABL2;CAMK2G GO:0002376| immune system process CAMK4;SRC;HCK;LYN GO:0007165| signal transduction SRC;BCR;MAP2K1;CSNK1G3;CAMK4;ABL2;LYN GO:0006915| apoptotic process SLK;ABL1 GO:0046777| protein autophosphorylation CLK3;CAMK4;ABL1;HCK;SRC;BCR;LYN;CAMK2G;SLK GO:0006464| protein modification process ABL2;ABL1;CSNK1G3 GO:0042127| regulation of cell proliferation ABL2;ABL1;SRC GO:0051353| positive regulation of oxidoreductase activity ABL1;ABL2 GO:0018108| peptidyl-tyrosine phosphorylation ABL2;LYN;CLK3;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0018105| peptidyl-serine phosphorylation CSNK1G3;CAMK4;SRC;CAMK2G;CDK2 GO:0030155| regulation of cell adhesion ABL2;ABL1 GO:0035556| intracellular signal transduction CAMK2G;LYN;CAMK4;BCR;SRC GO:2000145| regulation of cell motility ABL2;ABL1 GO:0006897| endocytosis ABL1;CSNK1G3 GO:2000249| regulation of actin cytoskeleton reorganization ABL2;ABL1 GO:0071300| cellular response to retinoic acid ABL2;LYN GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;SLK;MAP3K2 GO:0008360| regulation of cell shape CSNK1G3;HCK GO:0045087| innate immune response ABL2;LYN;SRC;HCK;ABL1 GO:0007155| cell adhesion HCK;SRC;ABL1;ABL2 GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2;SLK GO:0038083| ABL1;SRC;HCK;ABL2;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;SRC;MAP2K2;CAMK4 GO:0010506| regulation of autophagy ABL2;ABL1 GO:0023014| signal transduction via phosphorylation event LYN;SLK GO:0006954| inflammatory response CAMK4;HCK;LYN GO:0010976| positive regulation of neuron projection development LYN;ABL2 GO:0002250| adaptive immune response CAMK4;LYN 5368:[DB06616 DB08493] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08493|5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID MMP7 common genes common pathways GO:0071260| cellular response to mechanical stimulus MMP7;MAP3K2 GO:0031667| response to nutrient levels MMP7;SRC 5369:[DB06616 DB03850] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03850|Jaspisamide A ACTA1 common genes common pathways GO:0009612| response to mechanical stimulus ACTA1;SRC GO:0010628| positive regulation of gene expression SRC;ACTA1;MAP2K1 5370:[DB06616 DB09340] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09340|Tyropanoic acid GUSB common genes common pathways 5371:[DB06616 DB06248] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06248|Amelubant LTB4R2;LTB4R common genes common pathways GO:0006954| inflammatory response HCK;LTB4R;LYN GO:0006935| chemotaxis MAP2K1;LTB4R2 GO:0006928| cellular component movement LTB4R;MAP2K1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LTB4R2;LTB4R;LYN 5372:[DB06616 DB00716] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0050900| leukocyte migration LYN;FPR1;SRC GO:0006954| inflammatory response PTGDR;LYN;HCK;FPR1 GO:0006816| calcium ion transport CYSLTR1;CAMK2G GO:0038128| HSP90AA1;SRC GO:0038096| LYN;HSP90AA1;ABL1;HCK;SRC GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;HSP90AA1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;HSP90AA1;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0006935| chemotaxis FPR1;MAP2K1;CYSLTR1 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;HSP90AA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CYSLTR2;SRC;MAP2K2;MAP2K1;ABL1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;HSP90AA1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;FPR1;MAP2K2 GO:0007204| elevation of cytosolic calcium ion concentration FPR1;CYSLTR1;ABL1 GO:1900034| CAMK2G;HSP90AA1 GO:0007165| signal transduction LYN;HSP90AA1;CYSLTR2;PTGDR;MAP2K1;FPR1;CYSLTR1;BCR;SRC 5373:[DB06616 DB04685] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways GO:0014070| response to organic cyclic compound DUT;LYN GO:0006260| DNA replication CDK2;DUT 5374:[DB06616 DB04072] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04072|Alpha-Methylisocitric Acid ACO2 common genes common pathways 5375:[DB06616 DB00030] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0070447| positive regulation of oligodendrocyte progenitor proliferation LRP2;LYN GO:0006629| lipid metabolic process CYP3A4;LRP2 GO:0007399| nervous system development CAMK2G;LRP2;PCSK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RB1;CDK2 GO:0007155| cell adhesion HCK;IGFBP7;SRC;ABL1 GO:0007507| heart development MAP2K1;LRP2 GO:0032148| activation of protein kinase B activity SRC;INSR GO:0043066| negative regulation of apoptotic process IGF1R;SRC;HCK GO:0035556| intracellular signal transduction BCR;SRC;INSR;CAMK2G;LYN GO:0030514| negative regulation of BMP signaling pathway LRP2;ABL1 GO:0006897| endocytosis LRP2;ABL1 GO:0051726| regulation of cell cycle ABL1;BCR;SRC;RB1 GO:0008284| positive regulation of cell proliferation HCK;IGF1R;INSR;LYN;CDK2 GO:0002576| platelet degranulation SYTL4;LYN GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;INSR;LYN GO:0007265| Ras protein signal transduction RB1;CDK2 GO:0000082| G1/S transition of mitotic cell cycle CDK2;CAMK2G;RB1 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;SRC GO:0051301| cell division CDK2;RB1 GO:0016032| viral reproduction RB1;LYN;IDE;HCK;SRC GO:0050728| negative regulation of inflammatory response BCR;NOV GO:0001934| positive regulation of protein phosphorylation ABL1;INSR;LYN GO:0006914| autophagy ABL1;CTSD GO:0023014| signal transduction via phosphorylation event INSR;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;RB1;INSR;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent INSR;RB1;ABL1 GO:0007346| regulation of mitotic cell cycle MAP2K2;MAP2K1;RB1;MAP3K2 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;RB1 GO:0038083| IGF1R;INSR;LYN;SRC;HCK;ABL1 GO:0007050| cell cycle arrest RB1;MAP2K1;ABL1 GO:0030900| forebrain development SRC;LRP2 GO:0006887| exocytosis SYTL4;HCK GO:0007165| signal transduction LYN;IGF1R;BCR;SRC;MAP2K1 GO:0001843| neural tube closure LRP2;ABL1 GO:0045930| negative regulation of mitotic cell cycle RB1;ABL1 GO:0032869| cellular response to insulin stimulus INSR;SRC GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;IGF1R;INSR;MAP3K2;CAMK2G;LYN;CDK2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;INSR;IGF1R;LYN GO:0030335| positive regulation of cell migration IGF1R;INSR;LYN GO:0016310| phosphorylation IGF1R;INSR;MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0006464| protein modification process ABL1;CPE GO:0045892| negative regulation of transcription, DNA-dependent SRC;RB1 GO:0008285| negative regulation of cell proliferation RB1;LYN;MAP2K1;IGFBP7 GO:0007049| cell cycle SRC;CDK2;RB1 GO:0042359| vitamin D metabolic process LRP2;CYP3A4 GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;IGF1R;INSR;CAMK2G;LYN GO:0006915| apoptotic process RB1;ABL1 GO:0000187| activation of MAPK activity INSR;MAP3K2;MAP2K1;MAP2K2 GO:0014070| response to organic cyclic compound IGFBP7;LYN GO:0030182| neuron differentiation RB1;ABL1;MAP2K1 GO:0008283| cell proliferation SRC;LRP2 GO:0031175| neuron projection development RB1;LYN 5376:[DB06616 DB00796] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00796|Candesartan cilexetil AGTR1;CYP2C9;CYP2C8;UGT1A3;PTGS1;ABCB1 common genes CYP2C8;ABCB1 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS1;CYP2C8 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006954| inflammatory response HCK;PTGS1;LYN GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation SRC;PTGS1;AGTR1;ABL1 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;PTGS1;CYP2C8 GO:0050727| regulation of inflammatory response HCK;AGTR1;LYN GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS1 GO:0006082| organic acid metabolic process CYP2C8 GO:0002933| CYP2C8;CYP3A4 GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AGTR1 GO:0006979| response to oxidative stress ABL1;PTGS1 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A3;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0007165| signal transduction LYN;AGTR1;MAP2K1;BCR;SRC 5377:[DB06616 DB08482] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08482|[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER MMP1 common genes common pathways GO:0016032| viral reproduction LYN;HCK;SRC;MMP1 GO:0050900| leukocyte migration LYN;SRC;MMP1 5378:[DB06616 DB13967] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13967|Patent Blue ALB common genes common pathways GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 5379:[DB06616 DB07696] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0010033| response to organic substance CASP3;CDK2 GO:0006915| apoptotic process CASP3;ABL1 GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0014070| response to organic cyclic compound CASP3;LYN GO:0030182| neuron differentiation MAP2K1;CASP3;ABL1 GO:0030216| keratinocyte differentiation CASP3;MAP2K1 GO:0006974| response to DNA damage stimulus ABL1;CASP3;CDK2;LYN GO:0007507| heart development MAP2K1;CASP3 GO:0035556| intracellular signal transduction LYN;CAMK2G;CASP3;BCR;SRC GO:0043066| negative regulation of apoptotic process SRC;CASP3;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC;CASP3 GO:0042542| response to hydrogen peroxide SRC;CASP3 GO:0032496| response to lipopolysaccharide BCR;CASP3 GO:0001782| B cell homeostasis LYN;CASP3 GO:0030218| erythrocyte differentiation LYN;CASP3 GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0042493| response to drug LYN;SRC;ABCB1;CASP3 5380:[DB06616 DB13884] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways GO:0007596| blood coagulation F8;LYN;F10 GO:0030168| platelet activation F8;LYN;SRC GO:0030335| positive regulation of cell migration LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;F8 GO:0002576| platelet degranulation LYN;F8 5381:[DB06616 DB00275] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00275|Olmesartan AGTR1;ABCC2;SLCO1B3;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;ABCC2 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABCC2;ABL1 GO:0050727| regulation of inflammatory response HCK;AGTR1;LYN GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:0042127| regulation of cell proliferation AGTR1;ABL1;SRC GO:0055085| transmembrane transport SLCO1B1;ABCB11;SLCO1B3;ABCC2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0007165| signal transduction LYN;AGTR1;SRC;BCR;MAP2K1 GO:0006810| transport ABCB11;ABCC2;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ABL1 5382:[DB06616 DB03650] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03650|(3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One PIM1 common genes common pathways GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;PIM1;MAP3K2;CAMK2G;CDK2;LYN GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;PIM1;CDK2;LYN;CAMK2G GO:0006915| apoptotic process PIM1;ABL1 GO:0008283| cell proliferation SRC;PIM1 GO:0007049| cell cycle CDK2;PIM1;SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;PIM1;ABL1;HCK;BCR;SRC GO:0007275| multicellular organismal development CDK2;CAMK2G;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;HCK;SRC GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2;PIM1 5383:[DB06616 DB11995] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes CYP2C8;ABCB1 common pathways GO:0019221| cytokine-mediated signaling pathway MPL;HCK GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2C9 GO:2001225| regulation of chloride transport ABCB1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ABCB1;ABCG2;LYN GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006082| organic acid metabolic process CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:1901529| ABCB1 GO:0055085| transmembrane transport SLC22A8;ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0009636| response to toxin SLC22A8;LYN GO:0002933| CYP2C8;CYP3A4 GO:0008283| cell proliferation MPL;SRC GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0097267| CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 5384:[DB06616 DB06457] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06457|Tecastemizole KCNH2 common genes common pathways GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 GO:0006813| potassium ion transport CDK2;KCNH2 GO:0055085| transmembrane transport KCNH2;ABCB1 5385:[DB06616 DB05413] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05413|Tifuvirtide SERPINA5 common genes common pathways GO:0007596| blood coagulation LYN;SERPINA5 5386:[DB06616 DB07117] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways GO:0034614| cellular response to reactive oxygen species SRC;MMP9 GO:0048013| ephrin receptor signaling pathway MMP9;LYN;SRC GO:0030335| positive regulation of cell migration LYN;MMP9 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;MMP9 GO:0050900| leukocyte migration SRC;MMP9;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;MMP9 GO:0043065| positive regulation of apoptotic process ABL1;SRC;MMP9 GO:0043066| negative regulation of apoptotic process HCK;SRC;MMP9 5387:[DB06616 DB06371] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06371|Siplizumab CD2 common genes common pathways GO:1902715| ABL1;CD2 GO:0098609| CD2;SRC GO:0006915| apoptotic process CD2;ABL1 GO:0045580| regulation of T cell differentiation CD2;ABL1 GO:0007155| cell adhesion CD2;ABL1;HCK;SRC GO:0050900| leukocyte migration SRC;LYN;CD2 5388:[DB06616 DB06602] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06602|Reslizumab IL5 common genes common pathways GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;IL5;MAP2K2 GO:0071803| positive regulation of podosome assembly SRC;IL5 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;IL5;SRC GO:0019221| cytokine-mediated signaling pathway HCK;IL5 GO:0006954| inflammatory response LYN;HCK;IL5 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;IL5;SRC GO:0008284| positive regulation of cell proliferation IL5;HCK;LYN;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;IL5;BCR;SRC;ABL1;LYN 5389:[DB06616 DB04119] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CAMK2A;MAP2K1 GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;CAMK2A;SRC;HCK;ABL1 GO:0006464| protein modification process UBA1;ABL1 GO:0016310| phosphorylation ABL1;SRC;CAMK2A;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0030154| cell differentiation CAMK2G;CAMK2A;HCK GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;CAMK2A;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;CAMK2A;HCK GO:1900034| CAMK2G;CAMK2A GO:0006816| calcium ion transport CAMK2G;CAMK2A GO:0000082| G1/S transition of mitotic cell cycle CAMK2G;CDK2;CAMK2A GO:0000165| MAPKKK cascade CAMK2A;MAP2K2;MAP2K1;CAMK2G GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;CAMK2A;SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;CAMK2A;BCR GO:0007399| nervous system development CAMK2G;CAMK2A GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;UBA1 5390:[DB06616 DB07930] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways GO:0006629| lipid metabolic process ACOX1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;ACOX1;CYP2C8 5391:[DB06616 DB11949] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11949|Vestipitant TACR1 common genes common pathways GO:0010634| positive regulation of epithelial cell migration TACR1;SRC GO:0051602| response to electrical stimulus TACR1;SRC GO:0006954| inflammatory response LYN;TACR1;HCK GO:0007204| elevation of cytosolic calcium ion concentration TACR1;ABL1 GO:0007165| signal transduction TACR1;LYN;MAP2K1;SRC;BCR GO:0009725| response to hormone stimulus TACR1;LYN GO:0051496| positive regulation of stress fiber assembly TACR1;ABL1 GO:0014070| response to organic cyclic compound LYN;TACR1 5392:[DB06616 DB07500] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 GO:0006954| inflammatory response HCK;PLA2G2E;LYN 5393:[DB06616 DB03195] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03195|Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways GO:0007049| cell cycle CDK2;DTYMK;SRC GO:0008283| cell proliferation SRC;DTYMK GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;CDK2;LYN;DTYMK;CAMK2G 5394:[DB06616 DB01704] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways 5395:[DB06616 DB12874] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12874|Quizartinib FLT3 common genes common pathways GO:0046777| protein autophosphorylation FLT3;LYN;CAMK2G;ABL1;HCK;SRC;BCR GO:0043406| positive regulation of MAP kinase activity FLT3;SRC GO:0097028| dendritic cell differentiation LYN;FLT3 GO:0016310| phosphorylation MAP3K2;FLT3;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;FLT3;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN;FLT3 GO:0030154| cell differentiation HCK;FLT3;CAMK2G GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;FLT3;LYN;CDK2;CAMK2G GO:0030097| hemopoiesis LYN;FLT3 GO:0019221| cytokine-mediated signaling pathway FLT3;HCK GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein FLT3;LYN GO:0018108| peptidyl-tyrosine phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;FLT3;LYN GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;FLT3 GO:0042981| regulation of apoptotic process MAP3K2;FLT3;MAP2K1;MAP2K2 5396:[DB06616 DB05750] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05750|AVE-1625 CNR1 common genes common pathways GO:0010976| positive regulation of neuron projection development CNR1;LYN GO:0032496| response to lipopolysaccharide CNR1;BCR GO:0043065| positive regulation of apoptotic process CNR1;SRC;ABL1 GO:0007165| signal transduction CNR1;LYN;MAP2K1;BCR;SRC 5397:[DB06616 DB07127] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07127|{4-[2,2-BIS(5-METHYL-1,2,4-OXADIAZOL-3-YL)-3-PHENYLPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways GO:0006470| protein dephosphorylation CAMK2G;PTPRB 5398:[DB06616 DB05394] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05394|Corticorelin DBH common genes common pathways GO:0050900| leukocyte migration SRC;DBH;LYN GO:0055114| oxidation-reduction process CYP3A4;DBH;CYP2C8 GO:0042127| regulation of cell proliferation SRC;DBH;ABL1 5399:[DB06616 DB04115] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04115|Berberine BIRC5 common genes common pathways GO:0043066| negative regulation of apoptotic process BIRC5;HCK;SRC GO:0008284| positive regulation of cell proliferation BIRC5;HCK;CDK2;LYN GO:0042981| regulation of apoptotic process MAP2K1;BIRC5;MAP2K2;MAP3K2 GO:0045931| positive regulation of mitotic cell cycle BIRC5;ABL1 GO:0051301| cell division CDK2;BIRC5 GO:0006355| regulation of transcription, DNA-dependent ABL1;BIRC5 GO:0007346| regulation of mitotic cell cycle BIRC5;MAP2K1;MAP2K2;MAP3K2 GO:0000278| mitotic cell cycle ABL1;BIRC5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;BIRC5 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;BIRC5;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;BIRC5 GO:0007049| cell cycle CDK2;SRC;BIRC5 GO:0006915| apoptotic process ABL1;BIRC5 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1;BIRC5 5400:[DB06616 DB02660] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02660|Filaminast PDE4B common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;PDE4B;LYN GO:0050900| leukocyte migration LYN;PDE4B;SRC GO:0071222| cellular response to lipopolysaccharide ABL1;PDE4B;SRC;BCR 5401:[DB06616 DB13781] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13781|Xamoterol ADRB1 common genes common pathways GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0007165| signal transduction LYN;MAP2K1;BCR;ADRB1;SRC 5402:[DB06616 DB00465] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0042493| response to drug SRC;ABCB1;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN 5403:[DB06616 DB00720] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;LYN;HCK GO:0016032| viral reproduction LYN;SLC25A6;SLC25A4;HCK;SLC25A5;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042493| response to drug LYN;PTGS2;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0008284| positive regulation of cell proliferation HCK;SLC25A5;PTGS2;CDK2;LYN GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0055085| transmembrane transport SLC25A6;SLC25A4;SLC25A5;ABCB1 GO:0006915| apoptotic process SLC25A6;ABL1 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006810| transport SLC25A4;SLC25A5;ABCB1 5404:[DB06616 DB00653] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways GO:0055085| transmembrane transport CACNA1S;ABCB1;CACNA1C GO:0006810| transport ABCB1;CACNB1;CACNG1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CACNA1C GO:0006816| calcium ion transport CACNB2;CAMK2G;CACNA2D1;CACNA1S;CACNB1;CACNG1;CACNA1C GO:0051924| regulation of calcium ion transport CACNA2D1;CAMK2G GO:0007507| heart development MAP2K1;CACNA1C 5405:[DB06616 DB01147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A2;SLC15A1;SLC22A6 GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK 5406:[DB06616 DB02932] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02932|(R)-Bicalutamide AR common genes common pathways GO:0051259| protein oligomerization CAMK2G;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0008284| positive regulation of cell proliferation HCK;AR;LYN;CDK2 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;AR;MAP3K2;CDK2 GO:0006810| transport ABCB1;AR GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;AR GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 5407:[DB06616 DB00573] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0070542| response to fatty acid PTGS2;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;PPARG;LYN GO:0034605| cellular response to heat PTGS2;LYN GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance PTGS2;PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;PPARG;LYN GO:0014070| response to organic cyclic compound LYN;PPARG;PTGS2 GO:0032868| response to insulin stimulus LYN;PPARA GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK;PTGS2 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0002576| platelet degranulation LYN;ALB GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2;PPARG GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4;PPARA;PPARG GO:0007507| heart development PPARG;PPARA;MAP2K1 GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG;PPARA GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1;PTGS2 GO:0006954| inflammatory response PTGS2;LYN;HCK;PTGS1 GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;PPARA;PPARG GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG;PPARA GO:0042493| response to drug SRC;ABCB1;LYN;PPARG;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 5408:[DB06616 DB07677] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways GO:0006281| DNA repair PARP3;CDK2;ABL1 5409:[DB06616 DB09329] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways GO:0007596| blood coagulation LYN;VWF GO:0030168| platelet activation LYN;VWF;SRC GO:0007155| cell adhesion VWF;HCK;SRC;ABL1 GO:0002576| platelet degranulation LYN;VWF 5410:[DB06616 DB07592] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07592|(2R)-3-Methyl-1-phenyl-2-butanyl [(2S)-1-oxo-2-hexanyl]carbamate CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 5411:[DB06616 DB04117] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04117|4-(N,N-Dimethylamino)Cinnamoyl-Coa ECHS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ECHS1 5412:[DB06616 DB02758] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;HCK;LYN GO:0006629| lipid metabolic process CYP3A4;PLA2G2E 5413:[DB06616 DB07509] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug ABCB1;SRC;PPARG;LYN GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0014070| response to organic cyclic compound PPARG;LYN GO:0007165| signal transduction LYN;PPARG;MAP2K1;SRC;BCR GO:0032869| cellular response to insulin stimulus PPARG;SRC 5414:[DB06616 DB01647] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01647|Daxalipram PDE4B common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;PDE4B;LYN GO:0050900| leukocyte migration LYN;PDE4B;SRC GO:0071222| cellular response to lipopolysaccharide PDE4B;ABL1;BCR;SRC 5415:[DB06616 DB00869] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0071498| cellular response to fluid shear stress SRC;CA2 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0006979| response to oxidative stress CA3;ABL1 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0010033| response to organic substance CDK2;CA2 5416:[DB06616 DB02589] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02589|Se-Ethyl-Isoselenourea NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;NOS3 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;NOS3 GO:0043542| endothelial cell migration NOS3;ABL1 5417:[DB06616 DB04276] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04276|N-[N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-Butyl]-Guanidine CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CAPN1 5418:[DB06616 DB03849] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;PDE4B;PDE4D;LYN GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PDE4B;PDE4D GO:0050900| leukocyte migration PDE4D;LYN;SRC;PDE4B 5419:[DB06616 DB07701] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0006260| DNA replication ACHE;CDK2 5420:[DB06616 DB07561] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;ABL1;DHODH GO:0042493| response to drug DHODH;SRC;ABCB1;LYN GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0014070| response to organic cyclic compound DHODH;LYN 5421:[DB06616 DB00147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00147|Pyridoxal PDXK common genes common pathways GO:0008283| cell proliferation PDXK;SRC GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;PDXK;MAP2K2;BCR;SRC;MAP2K1;HCK 5422:[DB06616 DB01541] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01541|Boldenone AR common genes common pathways GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation AR;SRC GO:0010628| positive regulation of gene expression AR;MAP2K1;SRC GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0006810| transport ABCB1;AR GO:0007165| signal transduction LYN;AR;MAP2K1;BCR;SRC GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;AR;MAP3K2;CDK2 GO:0051259| protein oligomerization AR;CAMK2G GO:0008284| positive regulation of cell proliferation LYN;CDK2;AR;HCK GO:0042327| positive regulation of phosphorylation LYN;AR GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR 5423:[DB06616 DB00998] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0009636| response to toxin LYN;HTR1D GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0007165| signal transduction HTR1D;LYN;BCR;SRC;HTR1B;MAP2K1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug HTR1B;ABCB1;SRC;LYN;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0051385| response to mineralocorticoid stimulus HTR1B;SRC GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 5424:[DB06616 DB00133] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SPTLC2;SPTLC1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter SARS;CDK2 GO:0032496| response to lipopolysaccharide SRR;BCR GO:0042493| response to drug LYN;SRR;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent SARS;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CBS GO:0007420| brain development BCR;SRR GO:0014070| response to organic cyclic compound SRR;LYN GO:0055085| transmembrane transport SLC16A10;ABCB1 5425:[DB06616 DB07252] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07252|3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide EPHB4 common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;EPHB4 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;LYN;EPHB4 GO:0007155| cell adhesion EPHB4;ABL1;SRC;HCK GO:0048013| ephrin receptor signaling pathway LYN;EPHB4;SRC GO:0046777| protein autophosphorylation EPHB4;LYN;CAMK2G;HCK;SRC;BCR;ABL1 GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;EPHB4;CDK2;LYN;MAP3K2 GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;EPHB4;LYN;CDK2;CAMK2G GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;EPHB4;LYN 5426:[DB06616 DB05422] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05422|OPC-14523 SLC6A4 common genes common pathways GO:0007420| brain development SLC6A4;BCR GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0009636| response to toxin SLC6A4;LYN GO:0010033| response to organic substance CDK2;SLC6A4 GO:0010628| positive regulation of gene expression SRC;MAP2K1;SLC6A4 GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0042493| response to drug SLC6A4;ABCB1;SRC;LYN 5427:[DB06616 DB13749] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes ABL1 common pathways GO:0001934| positive regulation of protein phosphorylation ABL1;LYN GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0006914| autophagy ABL1 GO:0000278| mitotic cell cycle ABL1 GO:0050885| neuromuscular process controlling balance BCR;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:1901216| ABL1 GO:1904531| ABL1 GO:0010506| regulation of autophagy ABL1 GO:0006909| phagocytosis ABL1;HCK GO:1900042| ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0038083| LYN;SRC;HCK;ABL1 GO:0042493| response to drug ADCY1;SRC;ABCB1;LYN;ATP1A1 GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0030036| actin cytoskeleton organization BCR;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:1902036| ABL1 GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 GO:0038096| LYN;SRC;HCK;ABL1 GO:0042770| signal transduction in response to DNA damage ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization ABL1;HCK GO:0006298| mismatch repair ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0043542| endothelial cell migration ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0038189| ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:1905244| ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0030516| regulation of axon extension ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0006974| response to DNA damage stimulus LYN;CDK2;ABL1 GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0051882| mitochondrial depolarization ABL1 GO:0006281| DNA repair ABL1;CDK2 GO:2000772| regulation of cellular senescence ABL1 GO:0048668| collateral sprouting ABL1 GO:0045087| innate immune response LYN;ABL1;HCK;SRC GO:0007155| cell adhesion ABL1;SRC;HCK GO:0030155| regulation of cell adhesion ABL1 GO:0030035| microspike assembly ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:1900275| ABL1 GO:0006897| endocytosis ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:0035556| intracellular signal transduction ADCY1;BCR;SRC;LYN;GUCY1A2;CAMK2G GO:2000145| regulation of cell motility ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:1904528| ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0045580| regulation of T cell differentiation ABL1 GO:0002322| B cell proliferation involved in immune response ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0006915| apoptotic process ABL1 GO:0045184| establishment of protein localization ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0032868| response to insulin stimulus LYN;PFKFB1 GO:0042100| B cell proliferation ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;LYN GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0030182| neuron differentiation MAP2K1;ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:0006464| protein modification process ABL1 GO:0046632| alpha-beta T cell differentiation ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;HCK;ABL1 GO:0050853| B cell receptor signaling pathway ABL1;LYN GO:0001922| B-1 B cell homeostasis ABL1 GO:0009791| post-embryonic development ABL1 GO:1900272| ABL1 GO:1990051| ABL1 GO:0001843| neural tube closure ABL1 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0072358| cardiovascular system development ABL1 GO:0016310| phosphorylation CKB;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;CDK2;CAMK2G;PFKFB1;MAP3K2 GO:0030100| regulation of endocytosis ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:1903053| ABL1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0021587| cerebellum morphogenesis ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:1905555| ABL1 GO:1903351| ABL1 GO:0090135| actin filament branching ABL1 GO:0007165| signal transduction GUCY1A2;LYN;ADCY1;MAP2K1;SRC;BCR GO:0007420| brain development BCR;CKB GO:1902715| ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:0006813| potassium ion transport ATP1A1;CDK2 GO:1900026| ABL1 GO:0006979| response to oxidative stress ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:0048538| thymus development MAP2K1;ABL1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0048536| spleen development ABL1 5428:[DB06616 DB07173] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways GO:0016310| phosphorylation ADK;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 5429:[DB06616 DB08276] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08276|trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-) MYH14 common genes common pathways GO:0008360| regulation of cell shape MYH14;HCK 5430:[DB06616 DB02890] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways 5431:[DB06616 DB00066] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00066|Follitropin FSHR common genes common pathways GO:0007165| signal transduction LYN;SRC;FSHR;BCR;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;FSHR GO:0001545| primary ovarian follicle growth SRC;FSHR 5432:[DB06616 DB08809] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08809|Dichloroacetic Acid PDK1;GSTZ1 common genes common pathways GO:0016310| phosphorylation MAP3K2;PDK1;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;LYN;CDK2;PDK1;MAP3K2 GO:0008283| cell proliferation PDK1;SRC 5433:[DB06616 DB11595] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11595|Atezolizumab CD274 common genes common pathways GO:0030335| positive regulation of cell migration CD274;LYN GO:0031295| T cell costimulation LYN;CD274;SRC GO:0007165| signal transduction LYN;CD274;MAP2K1;BCR;SRC 5434:[DB06616 DB01751] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5435:[DB06616 DB11135] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways GO:0007165| signal transduction LYN;TXNRD1;MAP2K1;SRC;BCR GO:0008283| cell proliferation TXNRD1;SRC GO:0034599| cellular response to oxidative stress ABL1;GSR;TXNRD1 GO:0055114| oxidation-reduction process GSR;CYP2C8;TXNRD1;CYP3A4 5436:[DB06616 DB02774] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02774|1,3-Propandiol ARF1 common genes common pathways GO:0050690| regulation of defense response to virus by virus HCK;ARF1 5437:[DB06616 DB04856] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes CYP3A4 common pathways GO:0007165| signal transduction LYN;CCKAR;SRC;BCR;MAP2K1 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0030900| forebrain development CCKAR;SRC GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP3A5;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCKAR GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP3A4;CYP2C9 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8;CYP3A5 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP3A5;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 5438:[DB06616 DB01582] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01582|Sulfamethazine ALB common genes common pathways GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 5439:[DB06616 DB00397] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;ADRA2A;SRC GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;LYN;CDK2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA GO:0042493| response to drug LYN;DRD1;SRC;ABCB1 GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0030168| platelet activation SRC;ADRA2A;ADRA2C;LYN;ADRA2B GO:0030335| positive regulation of cell migration ADRA2A;DRD1;LYN GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0007165| signal transduction ADRA2C;ADRA2B;LYN;ADRB2;BCR;ADRB1;SRC;MAP2K1;ADRA2A;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:1903351| DRD1;ABL1 GO:0045453| bone resorption ADRB2;SRC GO:0000187| activation of MAPK activity MAP3K2;ADRA2B;MAP2K2;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0010628| positive regulation of gene expression SRC;MAP2K1;DRD1 5440:[DB06616 DB03944] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 5441:[DB06616 DB03413] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways GO:0014070| response to organic cyclic compound LYN;DUT GO:0006260| DNA replication CDK2;DUT 5442:[DB06616 DB04466] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04466|SR12813 NR1I2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CDK2;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0006805| xenobiotic metabolic process CYP2C8;NR1I2;CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;SRC;NR1I2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;NR1I2;LYN GO:0008202| steroid metabolic process NR1I2;CYP3A4;CYP2C8 GO:0042908| xenobiotic transport ABCB1;NR1I2 5443:[DB06616 DB07629] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07629|N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0007596| blood coagulation LYN;F10 GO:0030335| positive regulation of cell migration F10;LYN 5444:[DB06616 DB02115] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02115|Daidzin ALDH2;ABCG2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;ALDH2;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1;ABCG2 5445:[DB06616 DB09310] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways GO:0007596| blood coagulation F13B;LYN 5446:[DB06616 DB03706] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03706|1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane GSTM4 common genes common pathways 5447:[DB06616 DB08047] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08047|4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol ESR1;NCOA2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0060065| uterus development ESR1;SRC GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;CDK2 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA2;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 5448:[DB06616 DB05012] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0042493| response to drug ABCB1;SRC;LYN;SLC6A2 5449:[DB06616 DB07681] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07681|DODECANESULFONATE ION BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0042493| response to drug ABCB1;SRC;BCHE;LYN 5450:[DB06616 DB00728] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLC22A1;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0007165| signal transduction SRC;BCR;HTR3A;CHRNA2;MAP2K1;CHRM2;LYN GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM2;CAMK2G 5451:[DB06616 DB02636] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways GO:0006954| inflammatory response LYN;PLA2G2E;HCK GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 5452:[DB06616 DB03026] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03026|Phosphoglycolohydroxamic Acid TPI1;fucA common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;TPI1 5453:[DB06616 DB03017] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03017|Lauric Acid ADH5;fabB;GM2A;fabH;HNF4A;PLA2G2A;VLDLR;GLTP;fabF;LTF;tonB;C8G;PLA2G2D;LY96;TLR4;PPARA;ALB common genes common pathways GO:0007596| blood coagulation HNF4A;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;LYN;TLR4 GO:0032868| response to insulin stimulus PPARA;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;PLA2G2A;ABL1;TLR4 GO:0033690| positive regulation of osteoblast proliferation ABL1;LTF GO:0000187| activation of MAPK activity TLR4;MAP3K2;MAP2K1;MAP2K2 GO:0002322| B cell proliferation involved in immune response TLR4;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;LTF GO:0010628| positive regulation of gene expression SRC;MAP2K1;TLR4 GO:0007411| axon guidance SRC;VLDLR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;HNF4A GO:0008202| steroid metabolic process CYP2C8;CYP3A4;VLDLR GO:0002376| immune system process LYN;TLR4;LTF;HCK;LY96;C8G;SRC GO:0007165| signal transduction VLDLR;TLR4;LYN;SRC;BCR;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent HNF4A;LTF;ABL1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CDK2;MAP3K2;MAP2K2;HNF4A;SRC;MAP2K1 GO:0050885| neuromuscular process controlling balance ABL1;BCR;GM2A GO:0055114| oxidation-reduction process ADH5;CYP2C8;CYP3A4 GO:0006954| inflammatory response LY96;HCK;LYN;TLR4;PLA2G2D GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0050707| regulation of cytokine secretion TLR4;LYN GO:0001817| regulation of cytokine production LTF;LYN GO:0032496| response to lipopolysaccharide LY96;BCR;ADH5;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;LTF;ABL1 GO:0050727| regulation of inflammatory response TLR4;LYN;HCK GO:0002576| platelet degranulation LYN;ALB GO:0071222| cellular response to lipopolysaccharide TLR4;ABL1;LY96;BCR;SRC GO:0006805| xenobiotic metabolic process HNF4A;CYP2C8;CYP3A4 GO:0006897| endocytosis ABL1;VLDLR GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;LYN;HCK;LY96 GO:0043066| negative regulation of apoptotic process HCK;SRC;LTF;ALB GO:0045087| innate immune response LYN;TLR4;ABL1;LTF;C8G;SRC;LY96;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;VLDLR;CDK2 GO:0007507| heart development MAP2K1;PPARA GO:0007399| nervous system development VLDLR;CAMK2G GO:0006629| lipid metabolic process PLA2G2D;VLDLR;PPARA;CYP3A4;GM2A;HNF4A;PLA2G2A GO:0071260| cellular response to mechanical stimulus MAP3K2;TLR4 5454:[DB06616 DB04436] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04436|3-Fluorotyrosine SOD2 common genes common pathways GO:0055114| oxidation-reduction process SOD2;CYP2C8;CYP3A4 GO:0034599| cellular response to oxidative stress SOD2;ABL1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;SOD2 GO:0030335| positive regulation of cell migration SOD2;LYN 5455:[DB06616 DB03825] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03825|Rhodamine 6G ABCC1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug SRC;ABCB1;LYN;ABCC1 5456:[DB06616 DB13876] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13876|Brofaromine MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4 5457:[DB06616 DB04374] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04374|4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;ABL1 GO:0055114| oxidation-reduction process HAO1;CYP3A4;CYP2C8 5458:[DB06616 DB09047] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0006974| response to DNA damage stimulus LYN;CDK2;TOP2A;ABL1 5459:[DB06616 DB01666] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;FST;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter FST;CDK2 5460:[DB06616 DB04121] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways GO:0050690| regulation of defense response to virus by virus ARF1;HCK 5461:[DB06616 DB08631] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08631|N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 5462:[DB06616 DB06249] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06249|Arzoxifene ESR1;ESR2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction ESR2;MAP2K1;BCR;SRC;LYN;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0060065| uterus development ESR1;SRC GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;ESR2;MAP3K2;ESR1;CDK2 5463:[DB06616 DB08564] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08564|(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide SRC common genes SRC common pathways GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;BCR GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion ABL1;SRC;HCK GO:0045087| innate immune response SRC;HCK;ABL1;LYN GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0045056| transcytosis SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:0086098| SRC GO:0016032| viral reproduction SRC;HCK;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| LYN;ABL1;HCK;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;MAP3K2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0038083| ABL1;SRC;HCK;LYN GO:0042493| response to drug SRC;ABCB1;LYN GO:0034332| adherens junction organization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0050900| leukocyte migration LYN;SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0045453| bone resorption SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1 GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0031295| T cell costimulation LYN;SRC GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0071456| cellular response to hypoxia SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0048477| oogenesis SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;BCR;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0045785| positive regulation of cell adhesion SRC 5464:[DB06616 DB04941] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04941|Crofelemer CFTR;ANO1 common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;ANO1 GO:0055085| transmembrane transport ABCB1;CFTR GO:0034605| cellular response to heat ANO1;LYN 5465:[DB06616 DB06133] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06133|Dimethylcurcumin AR common genes common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation AR;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;AR;LYN GO:0006810| transport ABCB1;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;AR;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation AR;HCK;LYN;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0051259| protein oligomerization AR;CAMK2G 5466:[DB06616 DB07193] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways GO:0031295| T cell costimulation LYN;DPP4;SRC GO:0043542| endothelial cell migration DPP4;ABL1 GO:0008284| positive regulation of cell proliferation DPP4;CDK2;LYN;HCK GO:0007155| cell adhesion SRC;HCK;ABL1;DPP4 5467:[DB06616 DB07754] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways 5468:[DB06616 DB12379] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;CYP2C8 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;AHR;MAP3K2 GO:0042493| response to drug CYP1A1;LYN;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;AHR GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;AHR;CYP2C8 GO:0009615| response to virus CYP1A1;SRC GO:0006915| apoptotic process ABL1;AHR GO:0002933| CYP2C8;CYP3A4;CYP1A1 GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0009636| response to toxin AHR;CYP1A1;LYN GO:0008283| cell proliferation SRC;CYP1A1 GO:0010033| response to organic substance CDK2;CYP1A1 GO:0007049| cell cycle SRC;AHR;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;AHR GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A1;CYP2C8 GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A1;CYP3A4 5469:[DB06616 DB01576] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0009636| response to toxin LYN;SLC18A2 GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0008283| cell proliferation SRC;ADRA1B GO:0006915| apoptotic process ADRA1A;ABL1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A2;SLC18A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;ADRA1A;MAP2K1 GO:0009791| post-embryonic development SLC18A2;ABL1 GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0006810| transport ABCB1;SLC6A2 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A GO:0007165| signal transduction TAAR1;LYN;BCR;SRC;ADRA1A;MAP2K1;ADRA1B GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0042493| response to drug SLC6A3;ABCB1;ADRA1A;SRC;LYN;SLC6A2 GO:0007275| multicellular organismal development ADRA1B;CDK2;CAMK2G GO:0035556| intracellular signal transduction CAMK2G;LYN;ADRA1B;SRC;ADRA1A;BCR 5470:[DB06616 DB03615] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03615|Ribostamycin P4HB;rpsL common genes common pathways GO:0034599| cellular response to oxidative stress P4HB;ABL1 GO:0055114| oxidation-reduction process P4HB;CYP3A4;CYP2C8 GO:0071456| cellular response to hypoxia SRC;P4HB 5471:[DB06616 DB11560] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11560|Lesinurad SLC22A12;SLC22A11;CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0042493| response to drug SLC22A12;ABCB1;SRC;LYN GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC22A11;SLC22A12 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 5472:[DB06616 DB13999] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0010033| response to organic substance CDK2;CALR GO:0050766| positive regulation of phagocytosis BCR;CALR GO:0045892| negative regulation of transcription, DNA-dependent CALR;SRC GO:0010628| positive regulation of gene expression CALR;SRC;MAP2K1 GO:0030182| neuron differentiation ABL1;MAP2K1;HSPA5 GO:0008283| cell proliferation SRC;LRP1 GO:0007596| blood coagulation F10;LYN;VWF;F9;LMAN1;F2;PROC GO:1900182| F2;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol F2;ABL1 GO:0051222| positive regulation of protein transport LRP1;SRC GO:1900026| ABL1;CALR GO:0032956| regulation of actin cytoskeleton organization LRP1;ABL1 GO:0030168| platelet activation SRC;F2;VWF;LYN GO:0030335| positive regulation of cell migration HSPA5;F10;LYN GO:0010595| positive regulation of endothelial cell migration CALR;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0090398| cellular senescence CALR;MAP2K1 GO:0010976| positive regulation of neuron projection development HSPA5;LYN GO:0050728| negative regulation of inflammatory response PROC;BCR GO:0001934| positive regulation of protein phosphorylation F2;ABL1;LYN GO:0055114| oxidation-reduction process PHYH;CYP3A4;CYP2C8 GO:0050900| leukocyte migration LYN;F2;PROC;SRC GO:0006909| phagocytosis LRP1;HCK;ABL1 GO:0042493| response to drug ABCB1;SRC;CALR;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;CALR GO:0006629| lipid metabolic process LRP1;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CALR GO:0007155| cell adhesion VWF;ABL1;SRC;HCK GO:0008360| regulation of cell shape HCK;F2 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;CALR GO:0006897| endocytosis ASGR2;ABL1;LRP1 GO:0043066| negative regulation of apoptotic process SRC;HCK;PROC;HSPA5 GO:0002576| platelet degranulation VWF;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;CALR;F2;HCK GO:0007275| multicellular organismal development F2;LRP1;CAMK2G;CDK2 GO:0045056| transcytosis LRP1;SRC 5473:[DB06616 DB07326] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07326|6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide KDR common genes common pathways GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;KDR;MAP2K1;HCK;ABL1 GO:0030154| cell differentiation CAMK2G;KDR;HCK GO:0016310| phosphorylation BCR;MAP2K2;SRC;KDR;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway KDR;HCK;LYN GO:0030335| positive regulation of cell migration LYN;KDR GO:0046777| protein autophosphorylation BCR;SRC;KDR;HCK;ABL1;CAMK2G;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;KDR;MAP2K1;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0008360| regulation of cell shape KDR;HCK GO:0008284| positive regulation of cell proliferation CDK2;LYN;KDR;HCK GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR GO:0043066| negative regulation of apoptotic process SRC;KDR;HCK GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0007275| multicellular organismal development KDR;CAMK2G;CDK2 GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0070371| ERK1 and ERK2 cascade MAP2K2;KDR;MAP2K1 GO:0016032| viral reproduction HCK;KDR;SRC;LYN GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;KDR GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;KDR GO:0038083| ABL1;SRC;KDR;HCK;LYN 5474:[DB06616 DB06205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes common pathways GO:0016477| cell migration TGFB1;SRC GO:0014070| response to organic cyclic compound TGFB1;LYN GO:0008283| cell proliferation SRC;TGFB1 GO:0006915| apoptotic process TGFB1;ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway TGFB1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade TGFB1;ABL1;SRC;MAP2K2;MAP2K1 GO:0010628| positive regulation of gene expression TGFB1;MAP2K1;SRC GO:0010033| response to organic substance TGFB1;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;TGFB1;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;TGFB1 GO:0043406| positive regulation of MAP kinase activity TGFB1;SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;TGFB1;LYN GO:0030335| positive regulation of cell migration LYN;TGFB1 GO:0045930| negative regulation of mitotic cell cycle TGFB1;ABL1 GO:0001843| neural tube closure ABL1;TGFB1 GO:0002513| tolerance induction to self antigen TGFB1;LYN GO:1903800| MAP2K2;MAP2K1;TGFB1 GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;TGFB1;MAP3K2;CAMK2G;CDK2;LYN GO:0022408| negative regulation of cell-cell adhesion TGFB1;ABL1 GO:1900182| TGFB1;SRC GO:0007050| cell cycle arrest TGFB1;MAP2K1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;TGFB1;MAP3K2 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;TGFB1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TGFB1 GO:0014003| oligodendrocyte development TGFB1;LYN GO:0042493| response to drug ABCB1;SRC;LYN;TGFB1 GO:0001934| positive regulation of protein phosphorylation LYN;TGFB1;ABL1 GO:0050900| leukocyte migration LYN;TGFB1;SRC GO:0006954| inflammatory response HCK;TGFB1;LYN GO:0000165| MAPKKK cascade TGFB1;CAMK2G;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade TGFB1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;TGFB1;LYN GO:0001933| negative regulation of protein phosphorylation TGFB1;LYN GO:0042127| regulation of cell proliferation SRC;ABL1;TGFB1 GO:2000249| regulation of actin cytoskeleton reorganization TGFB1;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;TGFB1;LYN GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0071560| cellular response to transforming growth factor beta stimulus SRC;TGFB1 GO:0002576| platelet degranulation ALB;LYN;TGFB1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;TGFB1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;TGFB1;HCK GO:0071260| cellular response to mechanical stimulus TGFB1;MAP3K2 GO:0050777| negative regulation of immune response TGFB1;LYN GO:0007507| heart development MAP2K1;TGFB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TGFB1;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;TGFB1 5475:[DB06616 DB11450] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 5476:[DB06616 DB01838] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5477:[DB06616 DB08020] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;ESR2;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0060065| uterus development ESR1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;ABL1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;ESR1;MAP2K1;SRC;MAP2K2;ESR2 5478:[DB06616 DB02236] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways GO:0010033| response to organic substance CDK2;GART 5479:[DB06616 DB01185] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0006810| transport AR;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction MAP2K1;SRC;BCR;AR;NR3C1;LYN;ESR1 GO:0008283| cell proliferation AR;SRC GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway PRLR;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0006915| apoptotic process NR3C1;ABL1 GO:0032868| response to insulin stimulus HSD11B2;LYN GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0051259| protein oligomerization AR;CAMK2G GO:0042327| positive regulation of phosphorylation AR;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;PRLR GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0060065| uterus development ESR1;SRC GO:0030155| regulation of cell adhesion ABL1;PRLR GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0008284| positive regulation of cell proliferation HCK;AR;LYN;CDK2 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;NR3C1;CDK2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent AR;SRC;MAP2K2;MAP2K1;ESR1;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;ABL1;AR GO:0042493| response to drug ABCB1;SRC;HSD11B2;LYN GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;HSD11B2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0051301| cell division CDK2;NR3C1 5480:[DB06616 DB08320] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08320|DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE ESR1;NCOA2 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;ESR1;MAP2K1;MAP2K2;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;ESR1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0060065| uterus development SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;ESR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 5481:[DB06616 DB01756] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 5482:[DB06616 DB08022] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08022|(2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;PIM1 GO:0007275| multicellular organismal development CDK2;CAMK2G;PIM1 GO:0007346| regulation of mitotic cell cycle PIM1;MAP3K2;MAP2K2;MAP2K1 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MAP3K2;PIM1 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;CDK2;LYN;CAMK2G;MAP3K2;PIM1 GO:0046777| protein autophosphorylation LYN;CAMK2G;PIM1;ABL1;HCK;SRC;BCR GO:0007049| cell cycle CDK2;PIM1;SRC GO:0008283| cell proliferation SRC;PIM1 GO:0006915| apoptotic process PIM1;ABL1 5483:[DB06616 DB07512] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07512|7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE MAOB common genes common pathways GO:0009636| response to toxin LYN;MAOB GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LYN;MAOB 5484:[DB06616 DB06926] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1 GO:0010033| response to organic substance PPARG;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0014070| response to organic cyclic compound LYN;PPARG GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PPARG GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;PPARG;CDK2;MAP3K2 GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0045087| innate immune response LYN;PPARG;HCK;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0007507| heart development PPARG;MAP2K1 5485:[DB06616 DB06691] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0006954| inflammatory response HRH1;LYN;HCK GO:0043114| regulation of vascular permeability HRH1;SRC;BCR GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport ABCB1;SLC22A5;SLC22A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction LYN;HRH1;MAP2K1;BCR;SRC GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 5486:[DB06616 DB07318] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;NOS2 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0042127| regulation of cell proliferation SRC;ABL1;NOS2 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NOS2 5487:[DB06616 DB08170] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08170|(1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE MMP7 common genes common pathways GO:0031667| response to nutrient levels MMP7;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;MMP7 5488:[DB06616 DB08180] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08180|2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE FNTA;PGGT1B common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FNTA GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PGGT1B 5489:[DB06616 DB08087] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;AR;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0051259| protein oligomerization CAMK2G;AR GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;AR GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0010628| positive regulation of gene expression AR;MAP2K1;SRC GO:0006810| transport ABCB1;AR GO:0007165| signal transduction LYN;AR;BCR;SRC;MAP2K1 5490:[DB06616 DB00146] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;VDR;SRC GO:0042359| vitamin D metabolic process CYP24A1;CYP27B1;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;VDR GO:0008285| negative regulation of cell proliferation LYN;CYP27B1;MAP2K1;VDR GO:0036378| CYP3A4;CYP27B1 GO:0007165| signal transduction LYN;MAP2K1;VDR;SRC;BCR GO:0006816| calcium ion transport VDR;CYP27B1;CAMK2G GO:0006355| regulation of transcription, DNA-dependent ABL1;VDR GO:0055114| oxidation-reduction process CYP24A1;CYP2C8;CYP3A4;CYP27B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VDR GO:0032496| response to lipopolysaccharide BCR;CYP27B1 GO:0007275| multicellular organismal development CDK2;CAMK2G;VDR 5491:[DB06616 DB08872] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways GO:0006816| calcium ion transport CACNA2D2;CACNA2D1;CAMK2G GO:0051924| regulation of calcium ion transport CACNA2D1;CAMK2G GO:0006810| transport SLC5A6;ABCB1 GO:0055085| transmembrane transport SLC5A6;SLC5A8;ABCB1 GO:0006915| apoptotic process ABL1;SLC5A8 5492:[DB06616 DB03065] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03065|7-Nitroindazole-2-Carboxamidine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 GO:0043542| endothelial cell migration NOS3;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;NOS3;HCK GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;NOS3 5493:[DB06616 DB06421] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways GO:0030900| forebrain development TOP2B;SRC GO:0006974| response to DNA damage stimulus TOP2A;CDK2;LYN;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;TOP2A 5494:[DB06616 DB13133] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0090263| positive regulation of canonical Wnt receptor signaling pathway COL1A1;SRC GO:0007596| blood coagulation COL1A1;ADAMTS13;F8;LYN GO:0009636| response to toxin LYN;ADAMTS13 GO:0007229| integrin-mediated signaling pathway HCK;ADAMTS13;SRC;ABL1 GO:0030168| platelet activation ADAMTS13;COL1A1;SRC;LYN;F8 GO:0030335| positive regulation of cell migration COL1A1;LYN GO:0043434| response to peptide hormone stimulus COL1A1;LYN GO:0050900| leukocyte migration LYN;SRC;COL1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;F8 GO:0042493| response to drug LYN;COL1A1;ABCB1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;COL1A1;SRC;MAP2K1;MAP3K2;CDK2 GO:0031667| response to nutrient levels COL1A1;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;COL1A1 GO:0002576| platelet degranulation LYN;F8 GO:0071222| cellular response to lipopolysaccharide ADAMTS13;BCR;SRC;ABL1 GO:0042542| response to hydrogen peroxide COL1A1;SRC GO:0071300| cellular response to retinoic acid LYN;COL1A1 GO:0009612| response to mechanical stimulus COL1A1;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC;COL1A1 5495:[DB06616 DB07977] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process DHODH;ABL1;SRC GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0042493| response to drug ABCB1;SRC;DHODH;LYN GO:0014070| response to organic cyclic compound DHODH;LYN 5496:[DB06616 DB00233] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0006979| response to oxidative stress ABL1;MPO;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0016310| phosphorylation HCK;MAP2K1;CHUK;SRC;MAP2K2;BCR;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;CHUK;MAP2K1;HCK;ABL1 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0034614| cellular response to reactive oxygen species SRC;CHUK GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance CHUK;CDK2;PTGS2 GO:0043200| response to amino acid stimulus CHUK;LYN GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0009636| response to toxin LYN;CHUK GO:0038095| CHUK;LYN GO:0009612| response to mechanical stimulus SRC;MPO GO:0043066| negative regulation of apoptotic process SRC;MPO;HCK;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0009615| response to virus CHUK;SRC GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;CHUK;SRC GO:0006629| lipid metabolic process PTGS2;CYP3A4;PLA2G2E GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0045087| innate immune response LYN;ABL1;CHUK;SRC;HCK GO:0042127| regulation of cell proliferation SRC;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR;MPO;CHUK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CHUK;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC;CHUK GO:0006954| inflammatory response HCK;PLA2G2E;CHUK;ALOX5;PTGS2;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CHUK;MAP3K2;CDK2 GO:0042493| response to drug SRC;CHUK;ABCB1;LYN;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;MPO;ALOX5;CYP2C8 5497:[DB06616 DB03183] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PDE4D GO:0050900| leukocyte migration PDE4D;LYN;SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PDE4D 5498:[DB06616 DB11606] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11606|Susoctocog alfa VWF common genes common pathways GO:0030168| platelet activation LYN;VWF;SRC GO:0007596| blood coagulation VWF;LYN GO:0007155| cell adhesion VWF;SRC;HCK;ABL1 GO:0002576| platelet degranulation LYN;VWF 5499:[DB06616 DB05155] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05155|CR665 OPRK1 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;OPRK1;LYN GO:0032868| response to insulin stimulus OPRK1;LYN GO:0071222| cellular response to lipopolysaccharide BCR;SRC;OPRK1;ABL1 5500:[DB06616 DB00561] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0042493| response to drug SRC;ABCB1;KCNK3;LYN GO:0006813| potassium ion transport KCNK3;CDK2;KCNK9 GO:0007420| brain development KCNK3;BCR GO:0071456| cellular response to hypoxia SRC;KCNK3 5501:[DB06616 DB02144] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PITPNA 5502:[DB06616 DB03021] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03021|Ulapualide A ACTA1 common genes common pathways GO:0009612| response to mechanical stimulus SRC;ACTA1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;ACTA1 5503:[DB06616 DB11455] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11455|Robenacoxib PTGS2 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;LYN;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042493| response to drug LYN;PTGS2;SRC;ABCB1 GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0014070| response to organic cyclic compound LYN;PTGS2 5504:[DB06616 DB07227] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07227|4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE FNTA;FNTB;PGGT1B common genes common pathways GO:0042127| regulation of cell proliferation SRC;ABL1;FNTB GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PGGT1B GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;SRC 5505:[DB06616 DB02955] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02955|Ricinoleic Acid CNR1;CNR2;TRPV1 common genes common pathways GO:0055085| transmembrane transport TRPV1;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;ABL1 GO:0006810| transport ABCB1;TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1;LYN GO:0034605| cellular response to heat LYN;TRPV1 GO:0007165| signal transduction CNR2;CNR1;LYN;MAP2K1;SRC;BCR GO:0065009| regulation of molecular function TRPV1;CAMK2G GO:0006954| inflammatory response CNR2;LYN;HCK;TRPV1 GO:0050728| negative regulation of inflammatory response CNR2;BCR GO:0010976| positive regulation of neuron projection development CNR1;LYN GO:0006816| calcium ion transport TRPV1;CAMK2G GO:0032496| response to lipopolysaccharide CNR2;CNR1;BCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;CDK2 GO:0006629| lipid metabolic process CYP3A4;TRPV1 GO:0043065| positive regulation of apoptotic process SRC;TRPV1;ABL1;CNR1 5506:[DB06616 DB02553] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways GO:0055114| oxidation-reduction process GSR;CYP2C8;CYP3A4 GO:0034599| cellular response to oxidative stress GSR;ABL1 5507:[DB06616 DB08529] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 5508:[DB06616 DB09266] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;MRC1;BCR GO:0006897| endocytosis MRC1;ABL1 GO:0016032| viral reproduction HCK;MRC1;SRC;LYN GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;MRC1 5509:[DB06616 DB02011] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways GO:0031667| response to nutrient levels SRC;OTC GO:0042493| response to drug LYN;ABCB1;SRC;OTC GO:0032868| response to insulin stimulus LYN;OTC 5510:[DB06616 DB04709] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction AR;MAP2K1;BCR;SRC;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;AR;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0051259| protein oligomerization AR;CAMK2G GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;AR 5511:[DB06616 DB01612] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0035556| intracellular signal transduction NPR1;SRC;BCR;LYN;CAMK2G GO:0043114| regulation of vascular permeability SRC;BCR;NPR1 GO:0055114| oxidation-reduction process ALDH2;CYP3A4;CYP2C8 GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;NPR1;HCK;MAP2K2;BCR;SRC;ABL1 5512:[DB06616 DB01777] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways GO:0032868| response to insulin stimulus AANAT;LYN GO:0014070| response to organic cyclic compound AANAT;LYN 5513:[DB06616 DB09220] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09220|Nicorandil ABCC9 common genes common pathways GO:0007165| signal transduction LYN;ABCC9;MAP2K1;SRC;BCR GO:0065009| regulation of molecular function ABCC9;CAMK2G GO:0006813| potassium ion transport ABCC9;CDK2 GO:0055085| transmembrane transport ABCB1;ABCC9 GO:0042493| response to drug LYN;ABCC9;ABCB1;SRC 5514:[DB06616 DB14518] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade APP;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;APP;ABL1;SRC GO:1901216| APP;ABL1 GO:0042493| response to drug SRC;ABCB1;LYN;ATP1A1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;APP GO:0001934| positive regulation of protein phosphorylation ABL1;APP;LYN GO:0050885| neuromuscular process controlling balance APP;ABL1;BCR GO:0006897| endocytosis ABL1;APP GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0042327| positive regulation of phosphorylation APP;LYN GO:0002576| platelet degranulation APP;TF;LYN;ALB GO:0043065| positive regulation of apoptotic process APP;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0007155| cell adhesion APP;ABL1;SRC;HCK GO:0045087| innate immune response HCK;SRC;ABL1;APP;LYN GO:0007399| nervous system development APP;CAMK2G GO:0045931| positive regulation of mitotic cell cycle APP;ABL1 GO:0043393| regulation of protein binding APP;SRC GO:0010628| positive regulation of gene expression APP;SRC;MAP2K1 GO:1900272| APP;ABL1 GO:0008285| negative regulation of cell proliferation LYN;APP;MAP2K1 GO:0031175| neuron projection development APP;LYN GO:0000187| activation of MAPK activity MAP3K2;APP;MAP2K1;MAP2K2 GO:0006915| apoptotic process APP;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;MAP2K1;SRC;MAP2K2;ABL1 GO:0006979| response to oxidative stress APP;ABL1 GO:0006813| potassium ion transport ATP1A1;CDK2 GO:0030900| forebrain development APP;SRC GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;APP;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP 5515:[DB06616 DB07921] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07921|2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;CDK2 GO:0010628| positive regulation of gene expression MAP2K1;MMP12;SRC 5516:[DB06616 DB07684] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;PLAT;SRC;BCR GO:0006464| protein modification process PLAT;ABL1 GO:0007596| blood coagulation PLAT;LYN 5517:[DB06616 DB07300] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PDPK1;SRC GO:0032148| activation of protein kinase B activity PDPK1;SRC GO:0035556| intracellular signal transduction LYN;PDPK1;CAMK2G;SRC;BCR GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;PDPK1;CAMK2G GO:0043304| regulation of mast cell degranulation PDPK1;LYN GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;PDPK1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;ABL1 GO:0030036| actin cytoskeleton organization PDPK1;BCR;ABL1 GO:0030168| platelet activation PDPK1;LYN;SRC GO:0032869| cellular response to insulin stimulus SRC;PDPK1 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;PDPK1;CAMK2G;MAP3K2 GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;PDPK1;MAP3K2 GO:0031295| T cell costimulation SRC;LYN;PDPK1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;PDPK1 GO:0016477| cell migration SRC;PDPK1 GO:0038095| LYN;PDPK1 GO:0046777| protein autophosphorylation HCK;SRC;BCR;ABL1;PDPK1;LYN;CAMK2G 5518:[DB06616 DB12733] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12733|Dipraglurant GRM5 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;GRM5;LYN GO:0001932| regulation of protein phosphorylation MAP2K1;GRM5;LYN 5519:[DB06616 DB02735] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways GO:0006706| steroid catabolic process CYP3A4;STS GO:0006629| lipid metabolic process CYP3A4;STS GO:0008202| steroid metabolic process CYP2C8;CYP3A4;STS 5520:[DB06616 DB00867] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 GO:0045453| bone resorption ADRB2;SRC GO:0007165| signal transduction ADRB2;LYN;SRC;BCR;MAP2K1 GO:0055114| oxidation-reduction process CYP3A4;PGD;CYP2C8 5521:[DB06616 DB02507] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 5522:[DB06616 DB03280] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03280|P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate DTYMK;tmk;tmk common genes common pathways GO:0016310| phosphorylation CAMK2G;LYN;CDK2;DTYMK;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0007049| cell cycle SRC;CDK2;DTYMK GO:0008283| cell proliferation SRC;DTYMK 5523:[DB06616 DB06150] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06150|Sulfadimethoxine CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 5524:[DB06616 DB03169] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03169|(S)-Hmg-Coa HMGCR common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4;HMGCR GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;HMGCR GO:0043407| negative regulation of MAP kinase activity LYN;HMGCR GO:0006629| lipid metabolic process HMGCR;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;HCK;HMGCR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HMGCR;HCK GO:0055114| oxidation-reduction process CYP2C8;HMGCR;CYP3A4 5525:[DB06616 DB01586] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;NR1H4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0002376| immune system process HCK;SRC;LYN;NR1H4 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0006810| transport ABCC2;ABCB1;SLC10A1;SLC10A2;ABCB11 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;AKR1C2 GO:0010033| response to organic substance ABCC4;CDK2 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLC10A2;ABCC4;SLC10A1;ABCB11;SLCO1A2 GO:0014070| response to organic cyclic compound LYN;ABCC4 GO:0045087| innate immune response ABL1;SRC;HCK;LYN;NR1H4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;CDK2 GO:0006629| lipid metabolic process AKR1C2;CYP3A4 GO:0002576| platelet degranulation ABCC4;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;AKR1C2;HCK GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;ABCC2;NR1H4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0071398| cellular response to fatty acid NR1H4;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;NR1H4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0032496| response to lipopolysaccharide BCR;ABCC2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade NR1H4;ABL1 GO:0046628| positive regulation of insulin receptor signaling pathway NR1H4;SRC GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C2;SRC GO:0006954| inflammatory response NR1H4;LYN;HCK GO:0050728| negative regulation of inflammatory response NR1H4;BCR GO:0016032| viral reproduction LYN;SLC10A1;HCK;SRC GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;ABCC4;CYP2C8;AKR1C2 GO:0042493| response to drug ABCC2;ABCB1;SRC;ABCC4;CYP2E1;LYN GO:0006355| regulation of transcription, DNA-dependent NR1H4;ABL1 5526:[DB06616 DB05495] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05495|PG-530742 MMP9 common genes common pathways GO:0048013| ephrin receptor signaling pathway MMP9;LYN;SRC GO:0034614| cellular response to reactive oxygen species MMP9;SRC GO:0030335| positive regulation of cell migration MMP9;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MMP9;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;MMP9;LYN GO:0050900| leukocyte migration LYN;MMP9;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;MMP9 GO:0043065| positive regulation of apoptotic process SRC;ABL1;MMP9 5527:[DB06616 DB11113] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways GO:0032496| response to lipopolysaccharide PTGER4;BCR GO:0071260| cellular response to mechanical stimulus PTGER4;MAP3K2 GO:0009612| response to mechanical stimulus PTGER4;SRC GO:0070371| ERK1 and ERK2 cascade PTGER4;MAP2K1;MAP2K2 GO:0050728| negative regulation of inflammatory response PTGER4;BCR GO:0007165| signal transduction LYN;PTGER4;PTGER3;SRC;BCR;MAP2K1 GO:0050715| positive regulation of cytokine secretion SRC;PTGER4 5528:[DB06616 DB12339] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12339|Radezolid RRBP1;NIP7 common genes common pathways 5529:[DB06616 DB11085] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11085|Resorcinol TPO common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;TPO;CYP3A4 GO:0006979| response to oxidative stress TPO;ABL1 5530:[DB06616 DB00372] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00372|Thiethylperazine DRD2;DRD1;DRD4 common genes common pathways GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;DRD2 GO:0048678| response to axon injury DRD2;LYN GO:0001932| regulation of protein phosphorylation MAP2K1;DRD1;LYN GO:0042493| response to drug DRD1;SRC;DRD2;ABCB1;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0030900| forebrain development DRD2;SRC GO:1903351| DRD1;ABL1 GO:0007165| signal transduction MAP2K1;DRD2;SRC;BCR;DRD1;LYN;DRD4 GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0010628| positive regulation of gene expression DRD1;SRC;MAP2K1 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0000187| activation of MAPK activity MAP3K2;DRD4;MAP2K2;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;DRD2;ABL1 GO:0009636| response to toxin LYN;DRD2 5531:[DB06616 DB07863] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA common genes common pathways GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RXRA;PPARG;NCOA2 GO:0007507| heart development PPARG;RXRA;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2;RXRA;PPARG GO:0042493| response to drug LYN;PPARG;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;ABL1 GO:0016032| viral reproduction LYN;RXRA;SRC;HCK GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction LYN;PPARG;MAP2K1;SRC;BCR GO:0014070| response to organic cyclic compound PPARG;LYN GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0010033| response to organic substance PPARG;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2;PPARG 5532:[DB06616 DB07932] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07932|dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate ESR1;NCOA2 common genes common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1;NCOA2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0060065| uterus development SRC;ESR1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ESR1;MAP3K2;MAP2K1;MAP2K2;SRC GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction SRC;BCR;MAP2K1;ESR1;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 5533:[DB06616 DB13772] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug LYN;CYP1A2;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 5534:[DB06616 DB03866] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance CDK2;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A4 GO:0042493| response to drug ABCB1;SRC;PTGS2;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;PTGS2;LYN 5535:[DB06616 DB01926] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01926|Carboxymycobactin S LCN2 common genes common pathways GO:0002376| immune system process LYN;SRC;LCN2;HCK GO:0006915| apoptotic process ABL1;LCN2 GO:0045087| innate immune response ABL1;HCK;LCN2;SRC;LYN 5536:[DB06616 DB02741] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02741|CD564 RARG common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;RARG GO:0008285| negative regulation of cell proliferation LYN;RARG;MAP2K1 GO:0001843| neural tube closure ABL1;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;ABL1 GO:0060324| face development MAP2K1;RARG GO:0043066| negative regulation of apoptotic process HCK;SRC;RARG GO:0071300| cellular response to retinoic acid RARG;LYN GO:0008284| positive regulation of cell proliferation RARG;HCK;LYN;CDK2 GO:0043065| positive regulation of apoptotic process RARG;ABL1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARG 5537:[DB06616 DB06077] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0016032| viral reproduction LYN;HTR2A;SRC;HCK GO:0042493| response to drug DRD2;SRC;ABCB1;LYN;HTR2A GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK GO:0035556| intracellular signal transduction DRD2;SRC;BCR;LYN;CAMK2G GO:0048678| response to axon injury LYN;DRD2 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;SRC;MAP2K2;MAP2K1;ABL1;HTR2A GO:0009636| response to toxin DRD2;LYN GO:0007165| signal transduction SRC;DRD2;BCR;MAP2K1;HTR2A;LYN GO:0030900| forebrain development DRD2;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A 5538:[DB06616 DB07215] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07215|2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID NCOA1;PPARA common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CDK2;NCOA1;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0007507| heart development PPARA;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;CDK2 GO:0006629| lipid metabolic process CYP3A4;PPARA GO:0043065| positive regulation of apoptotic process SRC;ABL1;NCOA1 GO:0032868| response to insulin stimulus PPARA;LYN 5539:[DB06616 DB03085] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03085|Glycolic acid G6PD;thiO common genes common pathways GO:0034599| cellular response to oxidative stress ABL1;G6PD GO:0006629| lipid metabolic process CYP3A4;G6PD GO:0055114| oxidation-reduction process CYP2C8;G6PD;CYP3A4 GO:0014070| response to organic cyclic compound G6PD;LYN GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;G6PD 5540:[DB06616 DB12579] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12579|JNJ-37822681 DRD2 common genes common pathways GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;DRD2 GO:0048678| response to axon injury LYN;DRD2 GO:0042493| response to drug LYN;ABCB1;SRC;DRD2 GO:0007165| signal transduction DRD2;SRC;BCR;MAP2K1;LYN GO:0030900| forebrain development SRC;DRD2 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;DRD2;MAP2K1;ABL1 GO:0009636| response to toxin LYN;DRD2 5541:[DB06616 DB03773] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A1;SLC16A7 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0050900| leukocyte migration SLC16A1;SRC;LYN 5542:[DB06616 DB07460] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTK2;LYN;CDK2;HCK GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PTK2 GO:0043066| negative regulation of apoptotic process SRC;HCK;PTK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;PTK2 GO:0008360| regulation of cell shape HCK;PTK2 GO:0045087| innate immune response SRC;HCK;ABL1;PTK2;LYN GO:0042127| regulation of cell proliferation PTK2;ABL1;SRC GO:0001932| regulation of protein phosphorylation MAP2K1;PTK2;LYN GO:0048870| cell motility MAP2K1;PTK2 GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;PTK2;LYN GO:0043542| endothelial cell migration ABL1;PTK2 GO:0007275| multicellular organismal development CDK2;PTK2;CAMK2G GO:2000811| negative regulation of anoikis SRC;PTK2 GO:0038096| LYN;PTK2;ABL1;HCK;SRC GO:0010632| regulation of epithelial cell migration SRC;PTK2 GO:0051897| positive regulation of protein kinase B signaling cascade PTK2;SRC GO:0000165| MAPKKK cascade PTK2;CAMK2G;MAP2K1;MAP2K2 GO:0038083| ABL1;SRC;HCK;LYN;PTK2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;PTK2 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;PTK2 GO:0022408| negative regulation of cell-cell adhesion ABL1;PTK2 GO:0007172| signal complex assembly SRC;PTK2 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;PTK2;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0030335| positive regulation of cell migration PTK2;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN;PTK2 GO:0007229| integrin-mediated signaling pathway PTK2;SRC;HCK;ABL1 GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;PTK2;CAMK2G GO:0046777| protein autophosphorylation LYN;PTK2;CAMK2G;ABL1;HCK;BCR;SRC GO:0007411| axon guidance SRC;PTK2 GO:0048013| ephrin receptor signaling pathway PTK2;LYN;SRC GO:0033628| regulation of cell adhesion mediated by integrin PTK2;LYN GO:0007179| transforming growth factor beta receptor signaling pathway PTK2;SRC 5543:[DB06616 DB04564] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04564|Gluconolactone LCT common genes common pathways 5544:[DB06616 DB05116] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05116|Thymectacin TYMS common genes common pathways GO:0042493| response to drug ABCB1;SRC;TYMS;LYN GO:0014070| response to organic cyclic compound LYN;TYMS GO:0009636| response to toxin TYMS;LYN 5545:[DB06616 DB00411] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0006260| DNA replication ACHE;CDK2 GO:0008284| positive regulation of cell proliferation HCK;CHRM1;LYN;CDK2 GO:0009615| response to virus CHRM2;SRC GO:0006629| lipid metabolic process CYP3A4;PLA2G4A GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0007399| nervous system development CHRM2;CAMK2G;CHRM1;CHRM3;ACHE GO:0042127| regulation of cell proliferation PLA2G4A;SRC;ABL1 GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0008283| cell proliferation SRC;CHRM4;CHRM1;ACHE;CHRM3 GO:0007165| signal transduction MAP2K1;CHRM4;CHRNA2;BCR;SRC;LYN;CHRM2;CHRM1;CHRM3 5546:[DB06616 DB04860] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04860|Isatoribine TLR7 common genes common pathways GO:0045087| innate immune response LYN;TLR7;HCK;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus TLR7;MAP3K2 GO:0001932| regulation of protein phosphorylation MAP2K1;LYN;TLR7 GO:0006954| inflammatory response HCK;TLR7;LYN GO:0002376| immune system process LYN;TLR7;HCK;SRC GO:0007165| signal transduction TLR7;LYN;BCR;SRC;MAP2K1 5547:[DB06616 DB00841] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ESR1;ADRA1A;ADRA1B;ABL1 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0007165| signal transduction ADRA1B;MAP2K1;SRC;ADRA1A;ADRB1;BCR;LYN;ADRB2;ESR1;ADRA1D GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0045453| bone resorption SRC;ADRB2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;ADRA1A GO:0006915| apoptotic process ABL1;ADRA1A GO:0008283| cell proliferation SRC;ADRA1B;ADRA1D GO:0014070| response to organic cyclic compound LYN;COMT GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K2;SRC;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007275| multicellular organismal development CAMK2G;CDK2;ADRA1D;ADRA1B GO:0032496| response to lipopolysaccharide COMT;BCR GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0008284| positive regulation of cell proliferation ADRA1D;LYN;CDK2;HCK GO:0035556| intracellular signal transduction BCR;ADRA1A;SRC;ADRA1B;CAMK2G;LYN GO:0060065| uterus development ESR1;SRC GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042493| response to drug ABCB1;SRC;ADRA1A;LYN;COMT GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;ESR1 5548:[DB06616 DB08228] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;NQO2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;NQO2;CYP2C8 5549:[DB06616 DB05046] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05046|V1003 OPRK1;OPRM1 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;OPRM1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;LYN;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0007165| signal transduction LYN;OPRM1;OPRK1;BCR;SRC;MAP2K1 5550:[DB06616 DB06871] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06871|17-METHYL-17-ALPHA-DIHYDROEQUILENIN ESR1;NCOA2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction ESR1;LYN;BCR;SRC;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0060065| uterus development SRC;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;ESR1;MAP3K2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1;NCOA2 GO:0008209| androgen metabolic process CYP3A4;ESR1 5551:[DB06616 DB06901] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 5552:[DB06616 DB07691] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways GO:0071456| cellular response to hypoxia PPARD;SRC GO:0030154| cell differentiation PPARD;CAMK2G;HCK GO:0010628| positive regulation of gene expression MAP2K1;SRC;PPARD GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARD GO:0010033| response to organic substance CDK2;PPARD GO:0008283| cell proliferation SRC;PPARD GO:0006915| apoptotic process PPARD;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;PPARD GO:0071222| cellular response to lipopolysaccharide PPARD;ABL1;SRC;BCR GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PPARD GO:0006629| lipid metabolic process PPARD;CYP3A4 GO:0007507| heart development PPARD;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARD GO:0042127| regulation of cell proliferation SRC;ABL1;PPARD GO:0050728| negative regulation of inflammatory response BCR;PPARD GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;PPARD;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent PPARD;ABL1 5553:[DB06616 DB01214] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction LYN;ADRB2;MAP2K1;BCR;SRC;ADRB1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 5554:[DB06616 DB00044] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00044|Lutropin alfa LHCGR common genes common pathways GO:0007165| signal transduction LYN;LHCGR;MAP2K1;BCR;SRC GO:0001545| primary ovarian follicle growth SRC;LHCGR 5555:[DB06616 DB08808] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction LYN;ADRB2;ADRB3;ADRB1;SRC;BCR;MAP2K1 GO:0045453| bone resorption ADRB2;SRC GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 5556:[DB06616 DB09092] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09092|Xanthinol RPL3;NNT;GAPDH;IDH3A;OGDH;MDH2 common genes common pathways GO:0055114| oxidation-reduction process NNT;OGDH;CYP2C8;IDH3A;MDH2;CYP3A4;GAPDH GO:0050715| positive regulation of cytokine secretion SRC;GAPDH GO:0006915| apoptotic process ABL1;GAPDH 5557:[DB06616 DB07693] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways GO:0006810| transport ABCB1;TTR 5558:[DB06616 DB07253] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07253|N'-(5-chloro-1,3-benzodioxol-4-yl)-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine EPHB4 common genes common pathways GO:0016310| phosphorylation MAP3K2;CAMK2G;EPHB4;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;EPHB4;LYN GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;EPHB4;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;LYN;EPHB4;CAMK2G GO:0048013| ephrin receptor signaling pathway LYN;EPHB4;SRC GO:0007155| cell adhesion SRC;HCK;ABL1;EPHB4 GO:0018108| peptidyl-tyrosine phosphorylation EPHB4;LYN;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0007275| multicellular organismal development EPHB4;CDK2;CAMK2G 5559:[DB06616 DB09290] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09290|Ramosetron HTR3A;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LYN;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0007165| signal transduction LYN;HTR3A;MAP2K1;SRC;BCR GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 5560:[DB06616 DB14059] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0048536| spleen development NFKB2;ABL1 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0007165| signal transduction NFKB1;MAP2K1;SRC;BCR;NFKB2;LYN GO:0070555| response to interleukin-1 SRC;RELA GO:0070542| response to fatty acid SRC;PTGS2 GO:0038095| NFKB1;RELA;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;RELA GO:0014070| response to organic cyclic compound RELA;PTGS2;LYN GO:0043200| response to amino acid stimulus LYN;RELA GO:0032868| response to insulin stimulus RELA;LYN GO:0006915| apoptotic process ABL1;NFKB1 GO:0070301| cellular response to hydrogen peroxide RELA;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent RELA;SRC;NFKB1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;NFKB1 GO:0010033| response to organic substance RELA;PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0032496| response to lipopolysaccharide BCR;NFKB2;RELA;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;RELA GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;RELA;NFKB1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;RELA;PTGS2;HCK GO:0071222| cellular response to lipopolysaccharide RELA;NFKB1;ABL1;SRC;BCR GO:0042542| response to hydrogen peroxide SRC;RELA GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response LYN;RELA;PTGS2;HCK GO:0043066| negative regulation of apoptotic process RELA;PTGS2;NFKB1;HCK;SRC GO:0009612| response to mechanical stimulus SRC;RELA GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NFKB2;RELA;NFKB1 GO:0045087| innate immune response HCK;SRC;NFKB1;ABL1;LYN;NFKB2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2;NFKB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NFKB2;RELA;ABL1;NFKB1 GO:0042493| response to drug RELA;PTGS2;LYN;ABCB1;SRC GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NFKB1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;RELA;MAP3K2;NFKB1;MAP2K2;SRC;MAP2K1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0050728| negative regulation of inflammatory response NFKB1;BCR GO:0006954| inflammatory response PTGS2;RELA;NFKB2;LYN;HCK;NFKB1 GO:0016032| viral reproduction RELA;LYN;SRC;HCK GO:0019221| cytokine-mediated signaling pathway HCK;RELA GO:0071498| cellular response to fluid shear stress SRC;PTGS2 5561:[DB06616 DB06064] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06064|KAI-1455 PRKCE common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;PRKCE GO:0002376| immune system process LYN;PRKCE;HCK;SRC GO:0030168| platelet activation SRC;LYN;PRKCE GO:0071456| cellular response to hypoxia PRKCE;SRC GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;CDK2;CAMK2G;PRKCE;MAP3K2 GO:0051279| regulation of release of sequestered calcium ion into cytosol LYN;PRKCE GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;PRKCE;LYN;CDK2;MAP3K2 GO:0007049| cell cycle PRKCE;CDK2;SRC GO:0006915| apoptotic process PRKCE;ABL1 GO:0010634| positive regulation of epithelial cell migration PRKCE;SRC GO:0007155| cell adhesion PRKCE;ABL1;SRC;HCK GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;PRKCE;HCK GO:0035556| intracellular signal transduction LYN;PRKCE;CAMK2G;BCR;SRC GO:0018105| peptidyl-serine phosphorylation SRC;PRKCE;CAMK2G;CDK2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;PRKCE GO:0030838| positive regulation of actin filament polymerization HCK;PRKCE GO:0038096| SRC;HCK;ABL1;PRKCE;LYN GO:0051301| cell division CDK2;PRKCE 5562:[DB06616 DB07517] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 5563:[DB06616 DB08157] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0071498| cellular response to fluid shear stress SRC;CA2 GO:0010033| response to organic substance CDK2;CA2 5564:[DB06616 DB01309] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01309|Insulin Glulisine INSR common genes common pathways GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;INSR;MAP3K2 GO:0032869| cellular response to insulin stimulus SRC;INSR GO:0030335| positive regulation of cell migration LYN;INSR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway INSR;LYN;HCK GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;INSR;MAP3K2;CDK2;LYN;CAMK2G GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;INSR GO:0046777| protein autophosphorylation INSR;CAMK2G;LYN;SRC;BCR;HCK;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;INSR;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0032148| activation of protein kinase B activity SRC;INSR GO:0035556| intracellular signal transduction INSR;CAMK2G;LYN;SRC;BCR GO:0008284| positive regulation of cell proliferation HCK;INSR;CDK2;LYN GO:0001934| positive regulation of protein phosphorylation LYN;INSR;ABL1 GO:0023014| signal transduction via phosphorylation event LYN;INSR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;MAP3K2;INSR GO:0038083| ABL1;HCK;SRC;LYN;INSR GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR 5565:[DB06616 DB00040] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;GLP2R;CDK2;LYN GO:0006887| exocytosis GCGR;HCK GO:0007165| signal transduction MAP2K1;SRC;BCR;GLP2R;GLP1R;GCGR;LYN GO:0065009| regulation of molecular function GCGR;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;GLP1R 5566:[DB06616 DB04016] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04016|2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid CTSG;CMA1 common genes common pathways GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;SRC;MAP2K2;BCR;CTSG;HCK;MAP2K1 GO:0071222| cellular response to lipopolysaccharide ABL1;CTSG;BCR;SRC GO:0050727| regulation of inflammatory response CMA1;HCK;LYN GO:0032496| response to lipopolysaccharide BCR;CTSG 5567:[DB06616 DB11087] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0010628| positive regulation of gene expression NR1I2;SRC;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;SRC GO:0008202| steroid metabolic process CYP2C8;CYP3A4;NR1I2 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;NR1I2 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1I2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CDK2;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0006805| xenobiotic metabolic process CYP3A4;NR1I2;CYP2C8 5568:[DB06616 DB06736] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1;ABL1 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006954| inflammatory response PTGS2;LYN;HCK;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0042493| response to drug PTGS2;LYN;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS2;CYP2C9;CYP3A4;PTGS1;CYP2C8 GO:0006979| response to oxidative stress ABL1;PTGS1;PTGS2 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0070542| response to fatty acid SRC;PTGS2 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN 5569:[DB06616 DB01700] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01700|AICA ribonucleotide ATIC common genes common pathways 5570:[DB06616 DB05455] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05455|SR 121463 AVPR1B common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;AVPR1B GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AVPR1B 5571:[DB06616 DB14034] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14034|Darglitazone PPARG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug LYN;PPARG;SRC;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;PPARG;MAP2K1;MAP2K2;SRC GO:0007507| heart development PPARG;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response PPARG;LYN;ABL1;SRC;HCK GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0014070| response to organic cyclic compound PPARG;LYN GO:0007165| signal transduction PPARG;LYN;BCR;SRC;MAP2K1 GO:0032869| cellular response to insulin stimulus PPARG;SRC 5572:[DB06616 DB03100] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03100|6-Nitroindazole NOS2;NOS3 common genes common pathways GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;NOS3;HCK GO:0043542| endothelial cell migration ABL1;NOS3 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation NOS2;SRC;ABL1 GO:0055114| oxidation-reduction process NOS2;CYP3A4;NOS3;CYP2C8 GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;NOS3;MAP2K1 5573:[DB06616 DB05959] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05959|ENMD-1198 TNFRSF11A;HIF1A;STAT3 common genes common pathways GO:0010628| positive regulation of gene expression STAT3;MAP2K1;HIF1A;SRC GO:0006928| cellular component movement MAP2K1;STAT3 GO:0001922| B-1 B cell homeostasis ABL1;HIF1A GO:0008285| negative regulation of cell proliferation STAT3;LYN;MAP2K1 GO:0010033| response to organic substance CDK2;STAT3 GO:0014070| response to organic cyclic compound LYN;STAT3 GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;HIF1A GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;STAT3 GO:0008283| cell proliferation SRC;STAT3 GO:0070555| response to interleukin-1 TNFRSF11A;SRC GO:0007165| signal transduction HIF1A;MAP2K1;SRC;BCR;TNFRSF11A;STAT3;LYN GO:0043434| response to peptide hormone stimulus STAT3;LYN GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;STAT3;MAP3K2 GO:0030154| cell differentiation HCK;HIF1A;CAMK2G GO:0071456| cellular response to hypoxia SRC;HIF1A GO:0016032| viral reproduction STAT3;LYN;HCK;SRC GO:0006954| inflammatory response LYN;STAT3;TNFRSF11A;HCK GO:0002250| adaptive immune response LYN;TNFRSF11A GO:0019221| cytokine-mediated signaling pathway STAT3;HCK GO:0045893| positive regulation of transcription, DNA-dependent STAT3;MAP3K2;CDK2;MAP2K2;SRC;MAP2K1;HIF1A GO:0042493| response to drug SRC;ABCB1;STAT3;LYN GO:0010629| negative regulation of gene expression HIF1A;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent HIF1A;ABL1;STAT3 GO:0043066| negative regulation of apoptotic process SRC;HIF1A;HCK;STAT3 GO:0008284| positive regulation of cell proliferation STAT3;LYN;CDK2;HCK;TNFRSF11A GO:0051726| regulation of cell cycle STAT3;BCR;SRC;ABL1 GO:0010634| positive regulation of epithelial cell migration HIF1A;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter STAT3;CDK2 GO:0007399| nervous system development CAMK2G;STAT3 GO:0042981| regulation of apoptotic process MAP3K2;TNFRSF11A;MAP2K2;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;SRC;HIF1A GO:0032496| response to lipopolysaccharide TNFRSF11A;BCR GO:0007275| multicellular organismal development TNFRSF11A;CDK2;CAMK2G GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;STAT3 5574:[DB06616 DB07559] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0055114| oxidation-reduction process DHODH;CYP2C8;CYP3A4 GO:0042493| response to drug DHODH;ABCB1;SRC;LYN GO:0043065| positive regulation of apoptotic process SRC;DHODH;ABL1 5575:[DB06616 DB00640] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways GO:0007417| central nervous system development SRC;LYN;ADORA2A GO:0031668| cellular response to extracellular stimulus LYN;ADORA2B GO:0016310| phosphorylation ABL1;ADK;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0000186| activation of MAPKK activity MAP3K2;ADORA1 GO:0007165| signal transduction SRC;BCR;ADORA2B;MAP2K1;ADORA1;ADORA3;ADORA2A;LYN GO:0007596| blood coagulation LYN;ADORA2A GO:0000187| activation of MAPK activity MAP3K2;ADORA2B;MAP2K1;MAP2K2 GO:0006915| apoptotic process ADORA2A;ABL1 GO:0045580| regulation of T cell differentiation ABL1;ADA GO:0030336| negative regulation of cell migration ADORA3;BCR GO:0008285| negative regulation of cell proliferation MAP2K1;ADORA2A;ADORA3;LYN;ADORA1 GO:0042542| response to hydrogen peroxide SRC;ADA GO:0043066| negative regulation of apoptotic process ADORA1;SRC;HCK;ADA GO:0007155| cell adhesion HCK;ADA;SRC;ABL1 GO:0007399| nervous system development CAMK2G;ADORA1 GO:0042493| response to drug SRC;ABCB1;ADA;ADORA2A;LYN GO:0006355| regulation of transcription, DNA-dependent ADORA2A;ABL1 GO:0006909| phagocytosis HCK;ABL1;ADORA1;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;ADORA2A GO:0050728| negative regulation of inflammatory response BCR;ADA;ADORA1;ADORA2A GO:0006954| inflammatory response LYN;ADORA2A;ADORA3;ADORA1;HCK GO:0051924| regulation of calcium ion transport ADORA2A;CAMK2G 5576:[DB06616 DB04429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04429|4'-Hydroxyflavanone SHBG common genes common pathways 5577:[DB06616 DB05018] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05018|Migalastat GLA;UGT1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;BCR GO:0042493| response to drug SRC;ABCB1;LYN;UGT1A1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;LYN GO:0010033| response to organic substance UGT1A1;CDK2 5578:[DB06616 DB08692] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 5579:[DB06616 DB03962] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways GO:0055114| oxidation-reduction process PGD;CYP3A4;CYP2C8 5580:[DB06616 DB06153] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CAMK2G;CDK2 GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0007507| heart development HTR2B;MAP2K1 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;ADRA2A;SRC GO:0007399| nervous system development CHRM2;CHRM1;CAMK2G;CHRM3 GO:0006629| lipid metabolic process CYP3A4;UGT2B10 GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation HTR2B;ADRA2A;HCK;CDK2;LYN;HTR2A;HTR1A;CHRM1;ADRA1D GO:0035556| intracellular signal transduction ADRA1B;ADRA1A;SRC;BCR;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process HTR2B;HCK;SRC GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0042493| response to drug LYN;HTR2A;HTR2B;HTR2C;ADRA1A;SRC;HTR1B;ABCB1 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;LYN;ABL1;SRC GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K2;MAP2K1 GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0016032| viral reproduction HCK;SRC;HTR2A;LYN GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ADRA1D;ADRA1B;ABL1;ADRA1A GO:0030168| platelet activation LYN;ADRA2B;ADRA2C;SRC;ADRA2A GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;HTR2B;ABL1 GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0007165| signal transduction HTR2C;HTR2B;ADRA1B;ADRA2A;BCR;HTR1B;SRC;ADRA1A;MAP2K1;HTR1A;ADRA2C;CHRM1;HTR2A;ADRA2B;LYN;CHRM2;ADRA1D;HRH1;CHRM3;HTR1D GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0050715| positive regulation of cytokine secretion SRC;HTR2B GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;ABL1;HTR2B;HTR2C;ADRA1A;SRC;MAP2K2;MAP2K1 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K2;MAP2K1 GO:0008283| cell proliferation SRC;ADRA1B;CHRM3;ADRA1D;CHRM1;HTR1A GO:0009636| response to toxin HTR1D;LYN GO:0043406| positive regulation of MAP kinase activity HTR2B;ADRA2A;SRC;HTR2A GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0006928| cellular component movement MAP2K1;ADRA2A 5581:[DB06616 DB00695] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABCC2;ABL1 GO:0002576| platelet degranulation ALB;LYN GO:0032496| response to lipopolysaccharide ABCC2;BCR;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0071498| cellular response to fluid shear stress SRC;CA2 GO:0042493| response to drug UGT1A1;LYN;SRC;ABCB1;ABCC2 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PGD GO:0006979| response to oxidative stress ABCC2;ABL1 GO:0006813| potassium ion transport CDK2;SLC12A1 GO:0017144| drug metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0006810| transport ABCB1;ABCC2;SLC12A1 GO:0010033| response to organic substance CA2;UGT1A1;CDK2 GO:0014070| response to organic cyclic compound UGT1A1;LYN GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport SLC12A1;ABCC2;SLC22A11;ABCB1;SLC22A5;SLC22A8;SLC22A6;SLCO2A1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;SLC22A5 5582:[DB06616 DB13152] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13152|Coagulation Factor IX Human F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0006464| protein modification process ABL1;GGCX GO:0008283| cell proliferation SRC;LRP1 GO:0007596| blood coagulation F8;LYN;F10;F11;GGCX;F7;F2 GO:0014070| response to organic cyclic compound LYN;F7 GO:0051222| positive regulation of protein transport LRP1;SRC GO:0009725| response to hormone stimulus LYN;F7 GO:1900182| SRC;F2 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;F2 GO:0032956| regulation of actin cytoskeleton organization LRP1;ABL1 GO:0030168| platelet activation SRC;F2;F8;LYN GO:0030335| positive regulation of cell migration LYN;F10;F7 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F7;F10 GO:0050900| leukocyte migration LYN;F2;SRC GO:0055114| oxidation-reduction process F8;CYP3A4;CYP2C8 GO:0001934| positive regulation of protein phosphorylation ABL1;F2;LYN GO:0006909| phagocytosis LRP1;HCK;ABL1 GO:0031667| response to nutrient levels SRC;F7 GO:0008360| regulation of cell shape HCK;F2 GO:0006629| lipid metabolic process LRP1;CYP3A4 GO:0002576| platelet degranulation LYN;F8 GO:0008284| positive regulation of cell proliferation CDK2;LYN;F2;HCK GO:0006897| endocytosis LRP1;ABL1 GO:0007275| multicellular organismal development F2;LRP1;CDK2;CAMK2G GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC GO:0045056| transcytosis SRC;LRP1 5583:[DB06616 DB09129] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09129|Chromic chloride INSR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR GO:0038083| LYN;INSR;ABL1;SRC;HCK GO:0006355| regulation of transcription, DNA-dependent INSR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent INSR;MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 GO:0023014| signal transduction via phosphorylation event LYN;INSR GO:0001934| positive regulation of protein phosphorylation LYN;INSR;ABL1 GO:0008284| positive regulation of cell proliferation HCK;INSR;LYN;CDK2 GO:0035556| intracellular signal transduction LYN;CAMK2G;INSR;SRC;BCR GO:0032148| activation of protein kinase B activity SRC;INSR GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;LYN;INSR GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;INSR;CAMK2G;LYN GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;INSR;MAP3K2 GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;INSR;MAP3K2;CAMK2G;LYN;CDK2 GO:0030335| positive regulation of cell migration INSR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;INSR;LYN GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;INSR;LYN;CDK2;CAMK2G GO:0032869| cellular response to insulin stimulus SRC;INSR 5584:[DB06616 DB06796] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;SOD2;MAP2K1 GO:0030335| positive regulation of cell migration SOD2;LYN GO:0043547| positive regulation of GTPase activity A2M;BCR GO:0051056| regulation of small GTPase mediated signal transduction A2M;BCR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;SOD2 GO:0034599| cellular response to oxidative stress SOD2;ABL1;SLC11A2 GO:0002576| platelet degranulation ALB;A2M;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 5585:[DB06616 DB06533] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1 GO:0032868| response to insulin stimulus PPARA;LYN GO:0014070| response to organic cyclic compound PPARG;LYN GO:0007165| signal transduction LYN;PPARG;MAP2K1;BCR;SRC GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA;ABL1 GO:0042493| response to drug ABCB1;SRC;PPARG;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;PPARA;PPARG;CDK2;SRC;MAP2K2;MAP2K1 GO:0007507| heart development PPARA;PPARG;MAP2K1 GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG;PPARA GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG 5586:[DB06616 DB06472] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0007596| blood coagulation LYN;ITGB3 GO:0030168| platelet activation SRC;ITGB3;LYN GO:0007229| integrin-mediated signaling pathway ITGA2B;ITGB3;HCK;SRC;ABL1 GO:0010595| positive regulation of endothelial cell migration ITGB3;ABL1 GO:0001934| positive regulation of protein phosphorylation ITGB3;ABL1;LYN GO:0050900| leukocyte migration LYN;SRC;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ITGB3;ABL1;LYN GO:0034446| substrate adhesion-dependent cell spreading ITGB3;SRC;ABL1 GO:0016032| viral reproduction ITGB3;HCK;SRC;LYN GO:0045124| regulation of bone resorption SRC;ITGB3 GO:0007155| cell adhesion ABL1;ITGB3;HCK;SRC;ITGA2B GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;ITGB3 GO:0002576| platelet degranulation LYN;ITGA2B;ITGB3 5587:[DB06616 DB07247] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC;F7;F3 GO:0031667| response to nutrient levels F7;SRC GO:0019221| cytokine-mediated signaling pathway F3;HCK GO:0051897| positive regulation of protein kinase B signaling cascade F7;SRC;F3 GO:0030335| positive regulation of cell migration LYN;F3;F7 GO:0009725| response to hormone stimulus F7;LYN GO:0007596| blood coagulation F3;LYN;F7 GO:0014070| response to organic cyclic compound F7;LYN 5588:[DB06616 DB07140] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4;CYP2C8 5589:[DB06616 DB00384] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;LYN;SRC;ABCB1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 5590:[DB06616 DB05916] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05916|CT-011 PDCD1 common genes common pathways GO:0007275| multicellular organismal development PDCD1;CAMK2G;CDK2 GO:0043066| negative regulation of apoptotic process PDCD1;HCK;SRC GO:0043065| positive regulation of apoptotic process PDCD1;ABL1;SRC GO:0031295| T cell costimulation SRC;LYN;PDCD1 GO:0007165| signal transduction BCR;SRC;MAP2K1;PDCD1;LYN GO:0002376| immune system process SRC;HCK;LYN;PDCD1 GO:0006915| apoptotic process ABL1;PDCD1 5591:[DB06616 DB07814] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07814|Gibberellic acid AADACL2 common genes common pathways 5592:[DB06616 DB01902] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways GO:0006464| protein modification process ABL1;ERO1B GO:0006887| exocytosis NSF;HCK GO:0006813| potassium ion transport CDK2;NSF GO:0055114| oxidation-reduction process ERO1B;CYP2C8;CYP3A4 5593:[DB06616 DB00060] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00060|Interferon beta-1a IFNAR1;IFNAR2 common genes common pathways GO:0019221| cytokine-mediated signaling pathway IFNAR1;HCK GO:0009615| response to virus IFNAR2;IFNAR1;SRC GO:0032496| response to lipopolysaccharide IFNAR1;BCR 5594:[DB06616 DB02568] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02568|Peldesine PNP common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;PNP 5595:[DB06616 DB04495] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04495|RU81843 SRC common genes SRC common pathways GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1 GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0043406| positive regulation of MAP kinase activity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0046777| protein autophosphorylation ABL1;HCK;BCR;SRC;LYN;CAMK2G GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0048477| oogenesis SRC GO:0071456| cellular response to hypoxia SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0031295| T cell costimulation SRC;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0060491| regulation of cell projection assembly SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050900| leukocyte migration LYN;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0034332| adherens junction organization SRC GO:0038083| HCK;SRC;ABL1;LYN GO:0042493| response to drug LYN;ABCB1;SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| SRC;HCK;ABL1;LYN GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0071498| cellular response to fluid shear stress SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0086098| SRC GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;LYN GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response LYN;HCK;SRC;ABL1 GO:0007155| cell adhesion ABL1;SRC;HCK GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK 5596:[DB06616 DB02271] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02271|S-(2-Oxo)Pentadecylcoa NMT2 common genes common pathways 5597:[DB06616 DB07079] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07079|3-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}propane-1-thiol ADAM17 common genes common pathways GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;ADAM17 GO:0042493| response to drug LYN;ADAM17;ABCB1;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;ADAM17 GO:0048870| cell motility MAP2K1;ADAM17 GO:0032496| response to lipopolysaccharide ADAM17;BCR GO:0051272| positive regulation of cellular component movement LYN;ADAM17 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;ADAM17 GO:0007155| cell adhesion SRC;HCK;ABL1;ADAM17 GO:0030335| positive regulation of cell migration LYN;ADAM17 GO:0048536| spleen development ADAM17;ABL1 5598:[DB06616 DB02838] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02838|3,4-Dihydro-2h-Pyrrolium-5-Carboxylate DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;CYP2C8;CYP3A4 5599:[DB06616 DB06750] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCB1 5600:[DB06616 DB00743] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00743|Gadobenic acid ALB common genes common pathways GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 5601:[DB06616 DB03609] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03609|3-Deoxyguanosine PNP common genes common pathways GO:0042493| response to drug PNP;LYN;ABCB1;SRC 5602:[DB06616 DB13949] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;CALR GO:0050766| positive regulation of phagocytosis BCR;CALR GO:0045892| negative regulation of transcription, DNA-dependent CALR;SRC GO:0010033| response to organic substance CDK2;CALR GO:0007596| blood coagulation LYN;ITGB3 GO:1900026| CALR;ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1;ITGB3;CALR GO:0007229| integrin-mediated signaling pathway SRC;HCK;ITGB3;ABL1 GO:0030168| platelet activation ITGB3;SRC;LYN GO:0090398| cellular senescence MAP2K1;CALR GO:0016032| viral reproduction ITGB3;HCK;SRC;TFRC;LYN GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;SRC;ABL1;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;CALR GO:0042493| response to drug ABCB1;SRC;CALR;LYN GO:0050900| leukocyte migration SRC;ITGB3;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;ITGB3;LYN GO:0008284| positive regulation of cell proliferation HCK;CALR;CDK2;LYN GO:0002576| platelet degranulation LYN;TF;ITGB3 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;ITGB3 GO:0006897| endocytosis ABL1;TFRC GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;CALR;MAP3K2 GO:0007155| cell adhesion HCK;ITGB3;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CALR GO:0045124| regulation of bone resorption SRC;ITGB3 GO:0042127| regulation of cell proliferation TFRC;ABL1;SRC 5603:[DB06616 DB08756] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08756|(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE PRKACA;PKIA;ROCK1;ROCK2 common genes common pathways GO:0048013| ephrin receptor signaling pathway ROCK2;LYN;SRC;ROCK1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;ROCK1;ROCK2 GO:0006915| apoptotic process ROCK1;ABL1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;PRKACA GO:0031175| neuron projection development LYN;ROCK1 GO:0007596| blood coagulation LYN;PRKACA GO:0007165| signal transduction LYN;ROCK1;BCR;SRC;MAP2K1 GO:0032956| regulation of actin cytoskeleton organization ROCK2;ROCK1;ABL1 GO:0006468| protein phosphorylation CAMK2G;ROCK2;CDK2;LYN;PRKACA;MAP3K2;ABL1;ROCK1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0034605| cellular response to heat PRKACA;LYN GO:0010595| positive regulation of endothelial cell migration ROCK2;ABL1 GO:0016310| phosphorylation ABL1;ROCK1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;ROCK2;CDK2;LYN;PRKACA;MAP3K2 GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2;PKIA GO:0030036| actin cytoskeleton organization ROCK2;ROCK1;ABL1;BCR GO:0001934| positive regulation of protein phosphorylation ABL1;ROCK2;LYN GO:0050900| leukocyte migration LYN;ROCK1;SRC GO:0010506| regulation of autophagy ABL1;ROCK1 GO:0051298| centrosome duplication ROCK2;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PKIA;CDK2 GO:2000145| regulation of cell motility ROCK2;ABL1;ROCK1 GO:0035556| intracellular signal transduction ROCK2;CAMK2G;LYN;ROCK1;SRC;BCR GO:0030155| regulation of cell adhesion ROCK1;ABL1;ROCK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;ROCK1;ROCK2 GO:0018105| peptidyl-serine phosphorylation SRC;PRKACA;CDK2;CAMK2G GO:0043393| regulation of protein binding SRC;PRKACA GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;PRKACA;LYN GO:0051894| positive regulation of focal adhesion assembly ROCK1;ABL1 5604:[DB06616 DB04404] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04404|Allosamizoline CHIT1 common genes common pathways 5605:[DB06616 DB01092] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A1;CYP2C8 GO:0097267| CYP2C8;CYP1A1 GO:0006813| potassium ion transport CDK2;ATP1A3;ATP1A1;ATP1A2 GO:0030154| cell differentiation SLCO4C1;HCK;CAMK2G GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0010033| response to organic substance CYP1A1;CDK2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0055085| transmembrane transport SLCO4C1;ABCB1;SLCO1B3;SLCO1B1;SLC22A8;SLCO1A2;SLCO1C1 GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0009636| response to toxin CYP1A1;SLC22A8;LYN GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0008283| cell proliferation CYP1A1;SRC GO:0071260| cellular response to mechanical stimulus ATP1A1;ATP1A2;MAP3K2 GO:0071300| cellular response to retinoic acid ATP1A3;LYN GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0009615| response to virus SRC;CYP1A1 GO:0007275| multicellular organismal development SLCO4C1;CDK2;CAMK2G GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0032496| response to lipopolysaccharide BCR;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A1;LYN;ATP1A3;ATP1A1;SRC;ABCB1 5606:[DB06616 DB01428] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01428|Oxybenzone PGR;AR;ESR1;ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ESR1;MAP3K2;ESR2;AR;MAP2K1;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;AR;ABL1;PGR GO:0010629| negative regulation of gene expression MAP2K2;PGR;MAP2K1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0060065| uterus development ESR1;SRC GO:0042327| positive regulation of phosphorylation AR;LYN GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0008284| positive regulation of cell proliferation HCK;AR;CDK2;LYN GO:0050727| regulation of inflammatory response HCK;ESR1;LYN GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1;AR;ESR2 GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0051259| protein oligomerization CAMK2G;AR GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0007165| signal transduction LYN;ESR1;MAP2K1;PGR;BCR;SRC;ESR2;AR GO:0006810| transport ABCB1;AR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0050847| progesterone receptor signaling pathway PGR;SRC 5607:[DB06616 DB01077] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways GO:0007155| cell adhesion PTPRS;HCK;SRC;ABL1 GO:0006810| transport ATP6V1A;ABCB1 GO:0006470| protein dephosphorylation PTPRS;CAMK2G 5608:[DB06616 DB03255] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03255|Phenol cobT;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation LYN;ALB 5609:[DB06616 DB07437] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07437|1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE UPP1 common genes common pathways 5610:[DB06616 DB05125] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05125|SC12267 DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;LYN GO:0042493| response to drug DHODH;SRC;ABCB1;LYN GO:0055114| oxidation-reduction process DHODH;CYP2C8;CYP3A4 GO:0043065| positive regulation of apoptotic process ABL1;DHODH;SRC 5611:[DB06616 DB04892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04892|Phenserine ACHE;BCHE;APP common genes common pathways GO:0007399| nervous system development CAMK2G;APP;ACHE GO:0045087| innate immune response ABL1;SRC;HCK;LYN;APP GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;APP GO:0002576| platelet degranulation APP;LYN GO:0042327| positive regulation of phosphorylation APP;LYN GO:0006897| endocytosis ABL1;APP GO:0043393| regulation of protein binding APP;SRC GO:0045931| positive regulation of mitotic cell cycle APP;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;APP GO:0006260| DNA replication CDK2;ACHE GO:0051897| positive regulation of protein kinase B signaling cascade APP;SRC GO:0050885| neuromuscular process controlling balance APP;BCR;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;APP;LYN GO:0042493| response to drug ABCB1;SRC;BCHE;LYN GO:0010629| negative regulation of gene expression APP;MAP2K2;MAP2K1 GO:1901216| ABL1;APP GO:0030900| forebrain development APP;SRC GO:0006979| response to oxidative stress APP;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration APP;ABL1 GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;APP;MAP3K2;LYN;CDK2;CAMK2G GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;APP;BCHE GO:1900272| ABL1;APP GO:0010628| positive regulation of gene expression SRC;MAP2K1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;MAP2K2;SRC;MAP2K1;ABL1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;APP GO:0006915| apoptotic process APP;ABL1 GO:0008283| cell proliferation ACHE;SRC GO:0031175| neuron projection development APP;LYN 5612:[DB06616 DB05487] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways GO:0006954| inflammatory response NFKB1;HCK;LYN;NFKB2 GO:0050728| negative regulation of inflammatory response BCR;NFKB1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ESR1;MAP3K2;NFKB1;MAP2K1;MAP2K2;SRC GO:0010629| negative regulation of gene expression ESR1;NFKB1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NFKB1;ESR1;NFKB2 GO:0071260| cellular response to mechanical stimulus NFKB1;MAP3K2 GO:0045087| innate immune response NFKB2;LYN;NFKB1;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NFKB2;CDK2;NFKB1 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0060065| uterus development ESR1;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;NFKB1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0071222| cellular response to lipopolysaccharide ABL1;NFKB1;BCR;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;NFKB1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0032496| response to lipopolysaccharide BCR;NFKB2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;NFKB1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NFKB1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0006915| apoptotic process ABL1;NFKB1 GO:0038095| NFKB1;LYN GO:0007165| signal transduction MAP2K1;SRC;BCR;NFKB1;NFKB2;LYN;ESR1 GO:0048536| spleen development ABL1;NFKB2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 5613:[DB06616 DB00942] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00942|Cycrimine CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0007399| nervous system development CHRM1;CAMK2G GO:0008283| cell proliferation CHRM1;SRC GO:0006464| protein modification process CHRM1;ABL1 GO:0007165| signal transduction SRC;BCR;MAP2K1;CHRM1;LYN 5614:[DB06616 DB02761] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways 5615:[DB06616 DB08201] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08201|(1S)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0042493| response to drug SRC;ABCB1;BCHE;LYN 5616:[DB06616 DB04761] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04761|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] MMP13 common genes common pathways 5617:[DB06616 DB08077] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways GO:0007596| blood coagulation HBB;LYN GO:0042542| response to hydrogen peroxide SRC;HBB;HBA1 5618:[DB06616 DB14533] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0048013| ephrin receptor signaling pathway SRC;LYN;MMP9 GO:0070301| cellular response to hydrogen peroxide MDM2;ABL1 GO:0043407| negative regulation of MAP kinase activity APOE;LYN GO:0071375| cellular response to peptide hormone stimulus SRC;MDM2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;JUP GO:0007049| cell cycle BRCC3;TP53;CDK2;SRC;TP73 GO:0010033| response to organic substance CDK2;SOD1 GO:0008285| negative regulation of cell proliferation LYN;HDAC1;HDAC4;APP;TP53;NME1;MAP2K1;TP73 GO:0014911| positive regulation of smooth muscle cell migration SRC;VTN;HDAC4 GO:0050766| positive regulation of phagocytosis C3;AHSG;BCR GO:0006464| protein modification process ABL1;CPE GO:0045892| negative regulation of transcription, DNA-dependent MT3;ENO1;SRC;HDAC1;HDAC4;MDM2;TP53 GO:1900272| ABL1;APOE;APP GO:0030336| negative regulation of cell migration KRT16;BCR GO:0050853| B cell receptor signaling pathway IGHA1;LYN;IGHM;ABL1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0010628| positive regulation of gene expression MT3;INS;MAP2K1;SRC;FN1;TP53;APP;MDM2;CLU;GSN GO:0034614| cellular response to reactive oxygen species SRC;MMP9;TP53 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MT3;MAP2K2;SRC;MAP2K1;FGA;S100A7;APP GO:0055085| transmembrane transport APOA1;ABCB1 GO:0045184| establishment of protein localization MDM2;ABL1 GO:0000187| activation of MAPK activity C5;SOD1;MAP3K2;APP;TP73;MAP2K2;MAP2K1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;MAP2K2;PRDX1 GO:0006915| apoptotic process PDCD6;TP73;MT3;ABL1;SIVA1;APP;TP53;S100A9;PARP1;S100A8;CLU;GSN;APLP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC;APOA1 GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;MT3 GO:0031175| neuron projection development APP;LYN GO:0007596| blood coagulation F13B;F12;C4BPB;KLKB1;LYN;HDAC1;HBB;SERPIND1;F2;KNG1;FGA;SERPINA1 GO:0030216| keratinocyte differentiation MAP2K1;DSP;KRT10;S100A7;KRT16 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TP73 GO:0038095| IGKV1-17;LYN;IGLV3-21 GO:0008283| cell proliferation KRT16;TP53;MT3;PRDX1;SRC GO:2000352| negative regulation of endothelial cell apoptosis FGA;ABL1 GO:0016477| cell migration BDKRB1;SRC;JUP GO:0043200| response to amino acid stimulus LYN;TP53 GO:0051496| positive regulation of stress fiber assembly APOA1;ABL1 GO:0050663| cytokine secretion AGT;LYN GO:0009636| response to toxin MDM2;MGMT;PON1;LYN GO:0014070| response to organic cyclic compound TP53;MGMT;LYN GO:0051056| regulation of small GTPase mediated signal transduction BCR;A2M GO:0007165| signal transduction FGA;MAP2K1;JUP;SRC;BCR;IGFALS;PDIA3;BDKRB1;LYN;C3;ESR1 GO:0003014| renal system process AGT;BCR GO:0007420| brain development MT3;BCR GO:0030900| forebrain development APP;SRC GO:1900182| PARP1;INS;SRC;F2 GO:0031648| protein destabilization MDM2;GSN;SRC GO:0065009| regulation of molecular function CAMK2G;IL3;AGT GO:0070555| response to interleukin-1 HDAC4;SRC GO:0070372| regulation of ERK1 and ERK2 cascade FN1;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol F2;ABL1;BDKRB1 GO:0007050| cell cycle arrest TP53;ABL1;TP73;MAP2K1 GO:0070542| response to fatty acid PON1;SRC GO:0032489| regulation of Cdc42 protein signal transduction ABL1;APOA1;APOE GO:0002376| immune system process FGA;HCK;C4B;FCN3;SRC;CFH;C8G;CFB;C4BPA;PGLYRP2;IGKV1-17;C1QB;C8A;S100A9;C8B;C4BPB;C1R;IGLV3-21;S100A8;CLU;IGHM;C1QC;LYN;C3;CFI;IGHA1;C1S;C5 GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest MDM2;TP53;CDK2 GO:0032463| negative regulation of protein homooligomerization SRC;CLU GO:0048538| thymus development ABL1;MAP2K1;SOD1 GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;MT2A;HCK GO:0006979| response to oxidative stress ABL1;MT3;KRT1;PRDX1;SOD1;APOE;APP;TP53 GO:1900026| APOA1;ABL1;FGA GO:0050715| positive regulation of cytokine secretion INS;SRC GO:0030154| cell differentiation HCK;NME1;KRT6A;TP53;CAMK2G GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;APP;MAP3K2;CAMK2G;LYN;CDK2 GO:0007229| integrin-mediated signaling pathway ABL1;APOA1;SRC;HCK GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:0071456| cellular response to hypoxia SRC;MT3;P4HB;MDM2;TP53 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;APP;BDKRB1;ABL1;AGT;KNG1 GO:0030168| platelet activation LYN;F2;FGA;SRC GO:0006810| transport TTR;ABCB1 GO:0010595| positive regulation of endothelial cell migration PDCD6;AGT;ABL1 GO:0016310| phosphorylation LYN;CDK2;CAMK2G;MAP3K2;NME1;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0030335| positive regulation of cell migration MMP9;LYN;INS GO:0072358| cardiovascular system development ABL1;APOE GO:0043547| positive regulation of GTPase activity A2M;BCR GO:0098609| SRC;JUP;DSP GO:0034605| cellular response to heat PDCD6;LYN;TP53 GO:0008202| steroid metabolic process APOA1;CYP2C8;APOBR;APOE;APOL1;CYP3A4 GO:0038096| IGLV3-21;LYN;SRC;HCK;ABL1;IGKV1-17 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;MMP9 GO:1902036| ABL1;TP73 GO:0031954| positive regulation of protein autophosphorylation SRC;INS GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TP53;APP;VTN;LYN;AGT;IL3;SRC;INS;ABL1 GO:0051924| regulation of calcium ion transport CAMK2G;AGT GO:0019221| cytokine-mediated signaling pathway HCK;IL3 GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1;FN1 GO:0000165| MAPKKK cascade CAMK2G;INS;MAP2K1;MAP2K2;IL3 GO:0002250| adaptive immune response FGA;JCHAIN;IGKV1-17;IGLV3-21;IGHM;LYN;IGHA1 GO:0046628| positive regulation of insulin receptor signaling pathway SRC;INS GO:0051897| positive regulation of protein kinase B signaling cascade APP;INS;SRC GO:0010976| positive regulation of neuron projection development AGT;NME1;APOE;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;AGT;MT3;APOA1 GO:0050728| negative regulation of inflammatory response BCR;APOA1;KRT1;APOE GO:0006954| inflammatory response LYN;KLKB1;C3;C5;HDAC4;KRT16;S100A9;BDKRB1;S100A8;KNG1;HCK;SERPINA3;C4B GO:0006298| mismatch repair TP73;ABL1 GO:0016032| viral reproduction IDE;LYN;HDAC1;APOA2;TP53;MDM2;SIVA1;TP73;SRC;CFH;HCK GO:0002762| negative regulation of myeloid leukocyte differentiation LYN;NME1 GO:0051301| cell division BRCC3;CDK2 GO:0050885| neuromuscular process controlling balance APP;BCR;ABL1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0050900| leukocyte migration IGLV3-21;IGHA1;FN1;IGHM;MMP9;LYN;SRC;F2;IGKV1-17;JCHAIN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;SRC;MT3 GO:0006914| autophagy TP53;S100A9;S100A8;ABL1 GO:0034332| adherens junction organization DSP;JUP;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;MT3;F2;MMP9;C3;LYN;APP GO:0055114| oxidation-reduction process P4HB;PDIA3;CYP3A4;SOD1;GAPDHS;CP;PRDX1;CCS;CYP2C8;ADH1C GO:0042493| response to drug MDM2;TP53;APOA2;HDAC4;MGMT;SOD1;LYN;HDAC1;ABCB1;TP73;SRC;NME1;APOA1 GO:0014003| oligodendrocyte development GSN;LYN GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K1;MAP2K2;TP73 GO:0010629| negative regulation of gene expression HDAC1;ESR1;MDM2;APP;NME1;HDAC8;AGT;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent HDAC4;ESR1;HDAC1;EEF1A1;TP53;PARP1;HDAC8;INS;ABL1;ENO1;TP73 GO:1901216| ABL1;PARP1;APP;APOE;CLU GO:0031667| response to nutrient levels SRC;PSPH;PON1;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC4;ESR1;HDAC1;CDK2;TP53;MAP3K2;MT3;MAP2K2;TP73;SRC;MAP2K1;AGT GO:0032148| activation of protein kinase B activity INS;MT3;SRC GO:0008360| regulation of cell shape F2;HCK;ALDOA;FN1 GO:0045597| positive regulation of cell differentiation INS;MAP2K1 GO:0007507| heart development MDM2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;APP;TP53;MDM2;ESR1;HDAC4;CDK2;HDAC1;ENO1;TP73;HDAC8 GO:0045087| innate immune response IGHM;C1QC;S100A7;LYN;C3;CFI;IGHA1;C1S;C5;KRT16;C1QB;C8A;S100A9;C8B;C4BPB;APCS;C1R;F12;APP;APOL1;S100A8;CLU;CFB;JCHAIN;C4BPA;PGLYRP2;ABL1;FGA;HCK;C4B;SRC;FCN3;CFH;C8G GO:0071801| regulation of podosome assembly GSN;SRC;HCK GO:0007155| cell adhesion APLP1;FN1;APP;VTN;ABL1;IGFALS;HCK;JUP;SRC GO:0042981| regulation of apoptotic process MAP3K2;TP53;ESR1;TP73;MAP2K2;AGT;MAP2K1;NME1 GO:0007399| nervous system development HDAC4;CAMK2G;APLP1;APP;NME1;IL3 GO:0051974| negative regulation of telomerase activity SRC;TP53 GO:0006281| DNA repair MGMT;CDK2;BRCC3;PARP1;ABL1;MPG GO:0006629| lipid metabolic process APOBR;APOA1;APOL1;APOE;CLU;CYP3A4;PON1;C3 GO:0071260| cellular response to mechanical stimulus MAP3K2;HDAC4;AGT GO:0006974| response to DNA damage stimulus BRCC3;TP53;PARP1;MGMT;LYN;CDK2;TP73;ABL1;MPG GO:0002576| platelet degranulation SERPINA1;APOA1;A2M;AHSG;ITIH3;FGA;KNG1;A1BG;SERPINA3;LYN;SOD1;APLP2;FN1;ITIH4;APP;TF;ORM2;CLU;ALDOA;SERPINA4 GO:0043065| positive regulation of apoptotic process ABL1;KNG1;TP73;SRC;SOD1;MMP9;TP53;APP;CLU GO:1901796| TP73;HDAC1;CDK2;MDM2;TP53 GO:0050727| regulation of inflammatory response HCK;AHSG;PGLYRP2;S100A8;S100A9;ESR1;LYN GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0071732| cellular response to nitric oxide CDK2;MT3 GO:0006935| chemotaxis MAP2K1;SERPIND1;C5;S100A9;S100A8 GO:0008284| positive regulation of cell proliferation HDAC4;FN1;LYN;HDAC1;CDK2;KRT6A;MDM2;INS;IL3;F2;AGT;HCK GO:0042542| response to hydrogen peroxide SRC;HBA1;HBB;SOD1 GO:0009615| response to virus CLU;ENO1;SRC GO:0031571| mitotic cell cycle G1/S transition DNA damage checkpoint TP73;TP53;CDK2 GO:0030514| negative regulation of BMP signaling pathway DAND5;ABL1 GO:0006897| endocytosis NME1;ABL1;APLP1;APP GO:0071398| cellular response to fatty acid SRC;NME1 GO:0043066| negative regulation of apoptotic process MGMT;MMP9;SOD1;HDAC1;TP53;MDM2;MT3;SRC;HCK GO:0042327| positive regulation of phosphorylation LYN;APP GO:0009612| response to mechanical stimulus BDKRB1;PSPH;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0030155| regulation of cell adhesion ABL1;GSN GO:0060065| uterus development SRC;ESR1 GO:0043393| regulation of protein binding SRC;APP;HDAC4 GO:0007265| Ras protein signal transduction CDK2;TP53 GO:0034599| cellular response to oxidative stress MGMT;HDAC1;SOD1;P4HB;PARP1;ABL1;MT3;PRDX1;CCS GO:0043542| endothelial cell migration S100A2;ABL1 GO:0007275| multicellular organismal development HRNR;F2;CAMK2G;CDK2;TPI1;TP53 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL3;LYN;HDAC1 GO:0048678| response to axon injury LYN;SOD1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;BCR;MAP2K2;SRC;IL3;MAP2K1;HCK;ABL1 GO:0042127| regulation of cell proliferation SRC;AGT;JUP;ABL1 GO:0030516| regulation of axon extension APOE;ABL1 GO:0001932| regulation of protein phosphorylation MAP2K1;APOA1;FN1;LYN GO:0032496| response to lipopolysaccharide BCR;S100A7;HDAC1;BDKRB1;S100A8 GO:0045931| positive regulation of mitotic cell cycle APP;MDM2;ABL1 GO:0051353| positive regulation of oxidoreductase activity CCS;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0001933| negative regulation of protein phosphorylation LYN;BDKRB1 5619:[DB06616 DB06837] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways 5620:[DB06616 DB07962] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways GO:0006810| transport ABCB1;TTR 5621:[DB06616 DB03861] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways GO:0048477| oogenesis SRC;HEXB GO:0006813| potassium ion transport CDK2;KCNMB2 GO:0065009| regulation of molecular function CAMK2G;KCNMB2 GO:0008360| regulation of cell shape HCK;HEXB GO:0050885| neuromuscular process controlling balance ABL1;HEXB;BCR 5622:[DB06616 DB07714] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways GO:0034599| cellular response to oxidative stress ABL1;GSR GO:0055114| oxidation-reduction process CYP3A4;GSR;CYP2C8 5623:[DB06616 DB01966] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways GO:0010506| regulation of autophagy PSAP;ABL1 GO:0002576| platelet degranulation PSAP;LYN GO:0006629| lipid metabolic process CYP3A4;PSAP 5624:[DB06616 DB04816] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04816|Dantron ALB common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation LYN;ALB 5625:[DB06616 DB04959] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04959|HspE7 KRT7;UBR4 common genes common pathways GO:0016032| viral reproduction HCK;SRC;LYN;KRT7;UBR4 5626:[DB06616 DB05076] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05076|Fenretinide RBP4 common genes common pathways GO:0060065| uterus development RBP4;SRC GO:0007507| heart development RBP4;MAP2K1 5627:[DB06616 DB04846] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;CDK2;LYN GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0030168| platelet activation ADRA2A;SRC;LYN;ADRA2B;ADRA2C GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction ADRA2B;LYN;ADRB2;ADRA2C;MAP2K1;SRC;ADRB1;BCR;ADRB3;ADRA2A GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;ADRA2B GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;ADRB2 GO:0006928| cellular component movement MAP2K1;ADRA2A 5628:[DB06616 DB01893] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01893|N6-Benzyl Adenosine-5'-Diphosphate SRC common genes SRC common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;BCR;SRC;HCK GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1 GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0032463| negative regulation of protein homooligomerization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0060491| regulation of cell projection assembly SRC GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0071456| cellular response to hypoxia SRC GO:0016032| viral reproduction LYN;HCK;SRC GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0038096| LYN;SRC;HCK;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2 GO:0042493| response to drug LYN;SRC;ABCB1 GO:0038083| ABL1;SRC;HCK;LYN GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration LYN;SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR GO:0071398| cellular response to fatty acid SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0045087| innate immune response LYN;ABL1;SRC;HCK GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN 5629:[DB06616 DB08660] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08660|1,2,5,8-tetrahydroxyanthracene-9,10-dione CSNK2A1 common genes common pathways GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:0007165| signal transduction LYN;CSNK2A1;MAP2K1;BCR;SRC GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CSNK2A1;CAMK2G;CDK2;LYN GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;CSNK2A1 GO:0007049| cell cycle CDK2;CSNK2A1;SRC GO:0006915| apoptotic process CSNK2A1;ABL1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CSNK2A1;MAP2K1 5630:[DB06616 DB05713] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05713|LY-517717 F10 common genes common pathways GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC 5631:[DB06616 DB00992] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00992|Methyl aminolevulinate FCGR1A common genes common pathways GO:0007165| signal transduction FCGR1A;SRC;BCR;MAP2K1;LYN GO:0002376| immune system process LYN;FCGR1A;SRC;HCK GO:0060333| interferon-gamma-mediated signaling pathway FCGR1A;HCK;CAMK2G GO:0038096| FCGR1A;ABL1;HCK;SRC;LYN GO:0045087| innate immune response SRC;HCK;ABL1;FCGR1A;LYN 5632:[DB06616 DB03994] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03994|Ethanolamine ANXA3 common genes common pathways GO:0006909| phagocytosis ABL1;ANXA3;HCK GO:0010595| positive regulation of endothelial cell migration ABL1;ANXA3 5633:[DB06616 DB04400] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NOS2 GO:0007507| heart development TH;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0032496| response to lipopolysaccharide BCR;NOS2;TH GO:0051602| response to electrical stimulus SRC;TH GO:0042493| response to drug SRC;ABCB1;LYN;TH GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 GO:0006355| regulation of transcription, DNA-dependent ABL1;PCBD1 GO:0031667| response to nutrient levels SRC;TH GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;PCBD1;SRC;MAP2K2;CDK2;MAP3K2 GO:0055114| oxidation-reduction process TH;NOS2;CYP3A4;PAH;CYP2C8;PCBD1 GO:0043434| response to peptide hormone stimulus LYN;TH GO:0014070| response to organic cyclic compound TH;LYN 5634:[DB06616 DB01791] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways GO:0050900| leukocyte migration PDE4B;SRC;LYN;PDE4D GO:0071222| cellular response to lipopolysaccharide BCR;SRC;PDE4B;ABL1;PDE4D GO:0007165| signal transduction LYN;PDE4D;PDE4A;PDE4B;PDE4C;MAP2K1;SRC;BCR 5635:[DB06616 DB00896] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction BCR;SRC;MAP2K1;NR3C1;LYN GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0006915| apoptotic process ABL1;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0051301| cell division NR3C1;CDK2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 5636:[DB06616 DB04594] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways GO:0006629| lipid metabolic process HMGCL;CYP3A4 GO:0070542| response to fatty acid SRC;HMGCL 5637:[DB06616 DB00967] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes ABCB1 common pathways GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C9;CYP2C8;CYP2C19 GO:0007165| signal transduction LYN;HRH1;SRC;BCR;MAP2K1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2C9;CYP1A2 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006954| inflammatory response HRH1;LYN;HCK GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C19;CYP2C8 GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4;CYP2C9 GO:2001225| regulation of chloride transport ABCB1 GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP1A2;CYP2D6;CYP2C19;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2C9 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP1A2;CYP2D6 5638:[DB06616 DB03645] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;ENO3 5639:[DB06616 DB11827] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0010033| response to organic substance UGT1A1;CDK2 GO:0014070| response to organic cyclic compound LYN;UGT1A1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0055085| transmembrane transport ABCG2;SLC5A2;ABCB1 GO:0017144| drug metabolic process CYP3A4;UGT1A4;UGT1A1;UGT1A9;CYP2C8 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;UGT2B7;CYP2C8 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;SLC5A2;ABCB1 GO:0042493| response to drug LYN;UGT1A1;ABCG2;SRC;ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0006805| xenobiotic metabolic process UGT1A9;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation LYN;ALB GO:0006629| lipid metabolic process UGT2B7;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;BCR GO:1901529| ABCB1 5640:[DB06616 DB02581] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways GO:0002376| immune system process LYN;IL2;HCK;SRC GO:0065009| regulation of molecular function IL2;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;IL2 GO:0043066| negative regulation of apoptotic process IL2;HCK;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;IL2;HCK GO:0007155| cell adhesion SRC;HCK;ABL1;IL2 GO:0001933| negative regulation of protein phosphorylation IL2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL2 GO:0050728| negative regulation of inflammatory response IL2;BCR GO:0002250| adaptive immune response LYN;IL2 GO:0000165| MAPKKK cascade CAMK2G;IL2;MAP2K2;MAP2K1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;IL2 5641:[DB06616 DB06599] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06599|Lexatumumab TNFRSF10B common genes common pathways GO:0006915| apoptotic process ABL1;TNFRSF10B GO:0007165| signal transduction MAP2K1;BCR;SRC;TNFRSF10B;LYN GO:0006954| inflammatory response HCK;LYN;TNFRSF10B GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;TNFRSF10B GO:0050900| leukocyte migration SRC;TNFRSF10B;LYN GO:0071260| cellular response to mechanical stimulus MAP3K2;TNFRSF10B GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;TNFRSF10B;MAP3K2 GO:0007275| multicellular organismal development TNFRSF10B;CDK2;CAMK2G GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFRSF10B;ABL1 GO:0032496| response to lipopolysaccharide BCR;TNFRSF10B GO:0042127| regulation of cell proliferation TNFRSF10B;ABL1;SRC 5642:[DB06616 DB05552] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05552|TG100-115 PIK3CD;PIK3CG common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;PIK3CG GO:0007411| axon guidance SRC;PIK3CD GO:0050853| B cell receptor signaling pathway ABL1;PIK3CD;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;PIK3CD GO:0033628| regulation of cell adhesion mediated by integrin LYN;PIK3CG GO:0007165| signal transduction PIK3CD;LYN;SRC;BCR;MAP2K1 GO:0002376| immune system process HCK;SRC;LYN;PIK3CG;PIK3CD GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;PIK3CG;MAP3K2;PIK3CD GO:0030154| cell differentiation HCK;PIK3CD;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;PIK3CG GO:0030168| platelet activation SRC;PIK3CG;LYN;PIK3CD GO:0016310| phosphorylation CDK2;LYN;CAMK2G;PIK3CG;MAP3K2;PIK3CD;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0030335| positive regulation of cell migration PIK3CD;LYN GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CG;PIK3CD;SRC GO:0002250| adaptive immune response PIK3CD;PIK3CG;LYN GO:0006954| inflammatory response HCK;PIK3CD;PIK3CG;LYN GO:0045087| innate immune response ABL1;SRC;HCK;PIK3CG;LYN;PIK3CD GO:0006935| chemotaxis PIK3CD;PIK3CG;MAP2K1 GO:0006897| endocytosis PIK3CG;ABL1 GO:0001932| regulation of protein phosphorylation MAP2K1;PIK3CG;LYN 5643:[DB06616 DB07148] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07148|(6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one PREP common genes common pathways 5644:[DB06616 DB03132] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03132|3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid TPI1 common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;TPI1 5645:[DB06616 DB05471] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;NFKB1;LYN GO:0032496| response to lipopolysaccharide NFKB2;BCR GO:0045087| innate immune response NFKB2;LYN;NFKB1;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;CDK2;NFKB2 GO:0071260| cellular response to mechanical stimulus NFKB1;MAP3K2 GO:0071222| cellular response to lipopolysaccharide ABL1;NFKB1;SRC;BCR GO:0043066| negative regulation of apoptotic process HCK;SRC;NFKB1 GO:0010629| negative regulation of gene expression NFKB1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NFKB1;NFKB2 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;NFKB1;MAP3K2;CDK2 GO:0006954| inflammatory response NFKB1;HCK;LYN;NFKB2 GO:0050728| negative regulation of inflammatory response NFKB1;BCR GO:0007165| signal transduction LYN;NFKB2;MAP2K1;BCR;SRC;NFKB1 GO:0048536| spleen development ABL1;NFKB2 GO:0006915| apoptotic process NFKB1;ABL1 GO:0038095| NFKB1;LYN GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;NFKB1 GO:0045892| negative regulation of transcription, DNA-dependent NFKB1;SRC 5646:[DB06616 DB06870] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation AR;SRC GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction LYN;AR;SRC;BCR;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;SRC;AR GO:0051259| protein oligomerization AR;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0008284| positive regulation of cell proliferation LYN;CDK2;AR;HCK GO:0042327| positive regulation of phosphorylation LYN;AR 5647:[DB06616 DB07395] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways 5648:[DB06616 DB08119] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 5649:[DB06616 DB07072] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0008284| positive regulation of cell proliferation HCK;DPP4;CDK2;LYN GO:0007155| cell adhesion ABL1;HCK;SRC;DPP4 5650:[DB06616 DB06705] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06705|Gadofosveset trisodium ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation LYN;ALB 5651:[DB06616 DB08934] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08934|Sofosbuvir CTSA;HINT1;CMPK1;NME1;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0007165| signal transduction HINT1;LYN;SRC;BCR;MAP2K1 GO:0016310| phosphorylation ABL1;NME1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;CMPK1;MAP3K2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0030154| cell differentiation NME1;HCK;CAMK2G GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0008285| negative regulation of cell proliferation NME1;MAP2K1;LYN GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0006915| apoptotic process HINT1;ABL1 GO:0071398| cellular response to fatty acid SRC;NME1 GO:0006897| endocytosis NME1;ABL1 GO:0007399| nervous system development NME1;CAMK2G GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;NME1;MAP3K2 GO:1901529| ABCB1 GO:0010976| positive regulation of neuron projection development LYN;NME1 GO:0002762| negative regulation of myeloid leukocyte differentiation NME1;LYN GO:0010629| negative regulation of gene expression NME1;MAP2K2;MAP2K1 GO:0042493| response to drug ABCG2;NME1;SRC;ABCB1;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;HINT1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 5652:[DB06616 DB01640] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways GO:0007165| signal transduction LYN;BCR;PDE3B;SRC;MAP2K1 GO:0032869| cellular response to insulin stimulus SRC;PDE3B 5653:[DB06616 DB02762] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02762|RU79072 SRC common genes SRC common pathways GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0071456| cellular response to hypoxia SRC GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0036120| SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle CDK2;SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;LYN;CAMK2G GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC GO:0086098| SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response HCK;SRC;ABL1;LYN GO:0007155| cell adhesion ABL1;HCK;SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0035635| entry of bacterium into host cell SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0035556| intracellular signal transduction SRC;BCR;CAMK2G;LYN GO:0071398| cellular response to fatty acid SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0060065| uterus development SRC GO:0050900| leukocyte migration SRC;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0034332| adherens junction organization SRC GO:0042493| response to drug SRC;ABCB1;LYN GO:0038083| LYN;ABL1;HCK;SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0038096| LYN;HCK;SRC;ABL1 GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0038128| SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0016032| viral reproduction HCK;SRC;LYN 5654:[DB06616 DB07494] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07494|(3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE CHRFAM7A common genes common pathways GO:0007165| signal transduction CHRFAM7A;LYN;SRC;BCR;MAP2K1 5655:[DB06616 DB02988] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02988|Imino-Tryptophan DAO common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DAO 5656:[DB06616 DB05708] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;CHRNA7 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;CHRNA7 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1;CHRNA7 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;CHRNA7 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006816| calcium ion transport CAMK2G;CHRNA7 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug LYN;CYP2E1;CYP1A2;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP2E1;CYP3A4 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1;LYN 5657:[DB06616 DB08843] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08843|GS 0573 SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1 5658:[DB06616 DB00383] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRM3;CHRM1;LYN;CHRM2 GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0008283| cell proliferation SRC;CHRM1;CHRM3 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM2;CAMK2G;CHRM1;CHRM3 5659:[DB06616 DB07613] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 GO:0007165| signal transduction LYN;MAP2K1;SRC;HPGDS;BCR 5660:[DB06616 DB07261] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07261|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE F10 common genes common pathways GO:0007596| blood coagulation LYN;F10 GO:0030335| positive regulation of cell migration F10;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 5661:[DB06616 DB06849] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways 5662:[DB06616 DB00616] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00616|Candoxatril MME;ACE common genes common pathways 5663:[DB06616 DB08960] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08960|Hexamethonium CHRNA2 common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;CHRNA2 5664:[DB06616 DB06147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06147|Sulfathiazole CYP19A1 common genes common pathways GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP19A1 GO:0060065| uterus development CYP19A1;SRC 5665:[DB06616 DB06716] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;GABRB3 GO:0006810| transport GABRB3;ABCB1;GABRB2 GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation ALB;LYN GO:0032496| response to lipopolysaccharide ALPL;BCR 5666:[DB06616 DB01662] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways 5667:[DB06616 DB07350] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways GO:0010629| negative regulation of gene expression HDAC8;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;HDAC8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;CDK2 5668:[DB06616 DB07849] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN GO:0007417| central nervous system development GSTP1;SRC;LYN GO:0032869| cellular response to insulin stimulus SRC;GSTP1 GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0043200| response to amino acid stimulus LYN;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0009636| response to toxin LYN;GSTP1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1;GSTP1 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;GSTP1 GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process GSTP1;HCK;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ABL1 GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0014003| oligodendrocyte development GSTP1;LYN GO:0031667| response to nutrient levels GSTP1;SRC 5669:[DB06616 DB11855] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0007399| nervous system development CHRM3;CHRM2;CAMK2G;CHRM1 GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0009615| response to virus SRC;CHRM2 GO:0008284| positive regulation of cell proliferation CHRM1;LYN;CDK2;HCK GO:0002576| platelet degranulation ALB;LYN GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug SRC;ABCB1;ABCG2;LYN GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction LYN;CHRM2;CHRM1;CHRM3;CHRM5;MAP2K1;CHRM4;BCR;SRC GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0055085| transmembrane transport ABCG2;ABCB1;SLCO1B3;SLCO1B1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0008283| cell proliferation SRC;CHRM4;CHRM5;CHRM3;CHRM1 GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 5670:[DB06616 DB03297] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03297|Benzylsulfinic Acid HPN;SOD2;CMA1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD2;CYP2C8 GO:0050727| regulation of inflammatory response LYN;HCK;CMA1 GO:0043066| negative regulation of apoptotic process HPN;SRC;HCK GO:0008360| regulation of cell shape HPN;HCK GO:0034599| cellular response to oxidative stress SOD2;ABL1 GO:0010628| positive regulation of gene expression HPN;SRC;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;SOD2;MAP2K1 GO:0030335| positive regulation of cell migration SOD2;LYN 5671:[DB06616 DB01497] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;LYN;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;OPRM1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0007165| signal transduction OPRM1;OPRD1;LYN;BCR;SRC;OPRL1;MAP2K1;POMC;OPRK1;TRIM13 GO:0007204| elevation of cytosolic calcium ion concentration OPRL1;ABL1;OPRM1 GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G GO:0010629| negative regulation of gene expression OPRD1;MAP2K1;MAP2K2 GO:0071222| cellular response to lipopolysaccharide ABL1;OPRK1;BCR;SRC GO:0045087| innate immune response TRIM13;ABL1;HCK;SRC;LYN GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TRIM13 5672:[DB06616 DB00264] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0055085| transmembrane transport SLC22A2;ABCB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C19;CYP2C8 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007165| signal transduction SRC;ADRB1;BCR;MAP2K1;LYN;ADRB2 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0097267| CYP2C19;CYP2C8 GO:0045453| bone resorption SRC;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;SRC;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 5673:[DB06616 DB07007] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0071222| cellular response to lipopolysaccharide NOS2;BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0010629| negative regulation of gene expression NOS2;MAP2K1;MAP2K2 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 5674:[DB06616 DB09536] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09536|Titanium dioxide MARCO common genes common pathways GO:0002376| immune system process SRC;HCK;MARCO;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;MARCO;ABL1 GO:0045087| innate immune response ABL1;MARCO;SRC;HCK;LYN GO:0006897| endocytosis MARCO;ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;MARCO;ABL1 5675:[DB06616 DB03531] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03531|Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone DAO common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DAO 5676:[DB06616 DB05253] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05253|Proellex PGR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PGR GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;PGR GO:0050847| progesterone receptor signaling pathway PGR;SRC GO:0007165| signal transduction MAP2K1;PGR;BCR;SRC;LYN 5677:[DB06616 DB04418] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways GO:0002376| immune system process ADSSL1;SRC;HCK;LYN 5678:[DB06616 DB00523] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes ABCB1 common pathways GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007417| central nervous system development SRC;LYN;CYP26C1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0001843| neural tube closure RARA;RARG;ABL1 GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;IGFBP3;MAP2K1;RARA;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0007165| signal transduction LYN;CRABP1;BCR;CRABP2;SRC;MAP2K1;RARA;RARB GO:0006915| apoptotic process ABL1;IGFBP3 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0010628| positive regulation of gene expression SRC;RARA;MAP2K1;RARG GO:0008285| negative regulation of cell proliferation LYN;RARG;IGFBP3;MAP2K1;RARA;RARB GO:0045892| negative regulation of transcription, DNA-dependent SRC;RARA GO:0001933| negative regulation of protein phosphorylation IGFBP3;LYN GO:1901529| ABCB1 GO:0007275| multicellular organismal development CAMK2G;CDK2;CRABP1 GO:0071300| cellular response to retinoic acid RARG;RARA;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;RARB;RARA;RARG GO:0043065| positive regulation of apoptotic process IGFBP3;SRC;RARB;ABL1;RARG GO:0008284| positive regulation of cell proliferation CDK2;LYN;RARG;RARA;HCK;RARB GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;RARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;RARA;RARB;CDK2;RXRA GO:0007507| heart development RXRA;MAP2K1 GO:0042981| regulation of apoptotic process MAP3K2;IGFBP3;MAP2K2;MAP2K1;RARA GO:0045893| positive regulation of transcription, DNA-dependent RARA;MAP2K1;MAP2K2;SRC;CDK2;RXRA;MAP3K2 GO:0042493| response to drug SRC;ABCB1;LYN GO:0010629| negative regulation of gene expression MAP2K2;RARA;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent RXRB;RXRA;RARG;RXRG;ABL1;RARA;RARB;CRABP2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP26C1;CYP3A4;CYP2C8 GO:0016032| viral reproduction SRC;HCK;RXRA;LYN GO:0060324| face development RARA;MAP2K1;RARG 5679:[DB06616 DB00259] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19 GO:0042493| response to drug ABCB1;SRC;LYN;CYP2E1 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C8 GO:0097267| CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C19 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 5680:[DB06616 DB00306] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006281| DNA repair CDK2;ABL1;CHRNA4 GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;LYN;CDK2 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;LYN GO:0042493| response to drug LYN;GABRG3;SRC;ABCB1 GO:0006816| calcium ion transport CAMK2G;CHRNA4;CHRNA7 GO:0006810| transport ABCB1;GABRB3;GABRA3;GABRB1;GABRG2;GABRA5;GABRA1;GABRB2;GABRD;GABRA4;GRIK2;GABRA6 GO:0007417| central nervous system development SRC;GABRA4;LYN GO:0007165| signal transduction GABRE;GABRB1;GABRA5;GABRQ;GABRA6;GABRD;GABRP;LYN;BCR;GRIA2;CHRNA4;SRC;MAP2K1;GABRB3;CHRNA7 GO:0007420| brain development GABRA5;BCR GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2;CHRNA7 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;CHRNA7 GO:0009636| response to toxin GABRB1;LYN GO:0009791| post-embryonic development ABL1;GABRG2 5681:[DB06616 DB00288] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0043434| response to peptide hormone stimulus LYN;ANXA1 GO:0098609| ANXA1;SRC GO:0070555| response to interleukin-1 SRC;ANXA1 GO:0009725| response to hormone stimulus LYN;ANXA1 GO:0007165| signal transduction ANXA1;BCR;SRC;MAP2K1;LYN;NR3C1 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0002376| immune system process LYN;SRC;HCK;ANXA1 GO:0006915| apoptotic process ABL1;NR3C1 GO:0036378| CYP3A4 GO:0014070| response to organic cyclic compound ANXA1;LYN GO:0002933| CYP2C8;CYP3A4 GO:0030216| keratinocyte differentiation MAP2K1;ANXA1 GO:0007049| cell cycle CDK2;NR3C1;SRC GO:0046632| alpha-beta T cell differentiation ABL1;ANXA1 GO:0070301| cellular response to hydrogen peroxide ABL1;ANXA1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042127| regulation of cell proliferation ANXA1;ABL1;SRC GO:0006706| steroid catabolic process CYP3A4 GO:0030073| insulin secretion CAMK2G;ANXA1 GO:0006629| lipid metabolic process CYP3A4 GO:0008360| regulation of cell shape ANXA1;HCK GO:0045087| innate immune response ABL1;ANXA1;HCK;SRC;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0043066| negative regulation of apoptotic process ANXA1;SRC;HCK GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0043065| positive regulation of apoptotic process ANXA1;ABL1;SRC GO:0050727| regulation of inflammatory response HCK;ANXA1;LYN GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;ANXA1 GO:0008209| androgen metabolic process CYP3A4 GO:0006909| phagocytosis HCK;ABL1;ANXA1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0042493| response to drug ANXA1;ABCB1;SRC;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0002250| adaptive immune response ANXA1;LYN GO:0051301| cell division NR3C1;CDK2 GO:0006954| inflammatory response ANXA1;HCK;LYN 5682:[DB06616 DB08674] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08674|(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;SRC GO:0042127| regulation of cell proliferation SRC;ABL1;FNTB 5683:[DB06616 DB00156] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 5684:[DB06616 DB03095] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03095|Tetramethylammonium Ion GALE common genes common pathways 5685:[DB06616 DB13503] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13503|Tyrothricin ACHE common genes common pathways GO:0006260| DNA replication ACHE;CDK2 GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0008283| cell proliferation SRC;ACHE 5686:[DB06616 DB09279] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09279|Fimasartan AGTR1 common genes common pathways GO:0042127| regulation of cell proliferation SRC;AGTR1;ABL1 GO:0050727| regulation of inflammatory response LYN;HCK;AGTR1 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ABL1 GO:0007165| signal transduction BCR;SRC;MAP2K1;AGTR1;LYN 5687:[DB06616 DB03124] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0043200| response to amino acid stimulus CASP3;LYN GO:0030182| neuron differentiation ABL1;CASP3;MAP2K1 GO:0030216| keratinocyte differentiation CASP3;MAP2K1 GO:0006915| apoptotic process CASP3;ABL1 GO:0010033| response to organic substance CDK2;CASP3 GO:0030889| negative regulation of B cell proliferation CASP3;LYN GO:0042493| response to drug LYN;SRC;ABCB1;CASP3 GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0030218| erythrocyte differentiation CASP3;LYN GO:0001782| B cell homeostasis LYN;CASP3 GO:0032496| response to lipopolysaccharide CASP3;BCR GO:0043066| negative regulation of apoptotic process HCK;CASP3;SRC GO:0035556| intracellular signal transduction SRC;BCR;CASP3;CAMK2G;LYN GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;CASP3 GO:0006974| response to DNA damage stimulus ABL1;CASP3;LYN;CDK2 GO:0007507| heart development CASP3;MAP2K1 5688:[DB06616 DB08626] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08626|Thiorphan MME common genes common pathways 5689:[DB06616 DB05115] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05115|NN344 INSR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;INSR;MAP2K1;SRC;MAP2K2 GO:0038083| SRC;HCK;ABL1;INSR;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;INSR GO:0023014| signal transduction via phosphorylation event INSR;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR GO:0018108| peptidyl-tyrosine phosphorylation INSR;LYN;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G;INSR GO:0008284| positive regulation of cell proliferation HCK;INSR;CDK2;LYN GO:0032148| activation of protein kinase B activity SRC;INSR GO:0000187| activation of MAPK activity INSR;MAP3K2;MAP2K2;MAP2K1 GO:0046777| protein autophosphorylation CAMK2G;LYN;INSR;ABL1;SRC;BCR;HCK GO:0030335| positive regulation of cell migration INSR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;INSR;LYN GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;CDK2;CAMK2G;MAP3K2;INSR GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2;INSR GO:0032869| cellular response to insulin stimulus INSR;SRC 5690:[DB06616 DB08345] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08345|4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0006468| protein phosphorylation CSNK2A1;MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;CSNK2A1 GO:0007165| signal transduction CSNK2A1;LYN;MAP2K1;BCR;SRC GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CSNK2A1;MAP2K1 GO:0007049| cell cycle CSNK2A1;CDK2;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CSNK2A1 GO:1901796| CDK2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 5691:[DB06616 DB06042] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways GO:0000278| mitotic cell cycle ABL1;TUBB3 GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB;TUBB4A;CDK2 GO:0051301| cell division TUBB;CDK2 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0000086| G2/M transition of mitotic cell cycle TUBB;CDK2;TUBB4A;ABCB1 GO:0030182| neuron differentiation TUBB3;ABL1;MAP2K1 GO:0007411| axon guidance SRC;TUBB3 GO:0006928| cellular component movement MAP2K1;TUBB GO:0030900| forebrain development TOP2B;SRC 5692:[DB06616 DB01832] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01832|4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid FAH common genes common pathways 5693:[DB06616 DB03425] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006810| transport ABCB1;GRIK2 5694:[DB06616 DB08060] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways 5695:[DB06616 DB05264] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05264|NPI 32101 CSF2RB common genes common pathways GO:0065009| regulation of molecular function CAMK2G;CSF2RB GO:0007165| signal transduction LYN;CSF2RB;MAP2K1;BCR;SRC GO:0032496| response to lipopolysaccharide CSF2RB;BCR GO:0018108| peptidyl-tyrosine phosphorylation LYN;CSF2RB;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0000165| MAPKKK cascade CSF2RB;CAMK2G;MAP2K1;MAP2K2 GO:0019221| cytokine-mediated signaling pathway CSF2RB;HCK 5696:[DB06616 DB01742] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways GO:0050900| leukocyte migration LYN;PPIA;SRC GO:0016032| viral reproduction SRC;HCK;PPIA;LYN 5697:[DB06616 DB00750] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00750|Prilocaine SCN5A common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCB1 5698:[DB06616 DB05849] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05849|NCX 950 ADRB2 common genes common pathways GO:0007165| signal transduction LYN;ADRB2;MAP2K1;BCR;SRC GO:0045453| bone resorption SRC;ADRB2 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 5699:[DB06616 DB03470] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03470|Trypanothione TPR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;CDK2 GO:0016032| viral reproduction LYN;TPR;SRC;HCK GO:0051301| cell division CDK2;TPR GO:1900034| TPR;CAMK2G GO:0034605| cellular response to heat LYN;TPR GO:0007049| cell cycle SRC;CDK2;TPR 5700:[DB06616 DB02541] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02541|4-Hydroxybutan-1-Aminium PRSS3 common genes common pathways GO:0043542| endothelial cell migration ABL1;PRSS3 5701:[DB06616 DB08510] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08510|5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0002250| adaptive immune response LYN;IGHG2 GO:0038096| ABL1;SRC;HCK;LYN;IGHG2 GO:0045087| innate immune response ABL1;HCK;SRC;LYN;IGHG2 GO:0050853| B cell receptor signaling pathway ABL1;LYN;IGHG2 GO:0002376| immune system process SRC;HCK;LYN;IGHG2 5702:[DB06616 DB04445] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SULT2A1 GO:0008202| steroid metabolic process CYP3A4;SULT2A1;CYP2C8 5703:[DB06616 DB07964] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07964|(3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0048870| cell motility MAP2K1;ADAM17 GO:0032496| response to lipopolysaccharide BCR;ADAM17 GO:0051272| positive regulation of cellular component movement ADAM17;LYN GO:0008284| positive regulation of cell proliferation ADAM17;CDK2;LYN;HCK GO:0007155| cell adhesion ADAM17;ABL1;HCK;SRC GO:0007173| epidermal growth factor receptor signaling pathway ADAM17;ABL1;SRC GO:0042493| response to drug ABCB1;SRC;ADAM17;LYN GO:0001934| positive regulation of protein phosphorylation LYN;ADAM17;ABL1 GO:0030335| positive regulation of cell migration ADAM17;LYN GO:0048536| spleen development ADAM17;ABL1 5704:[DB06616 DB04133] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport SLC22A8;SLC22A5;SLC22A6;SLC22A11;ABCB1 5705:[DB06616 DB04934] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04934|Rifalazil rpoB;CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 5706:[DB06616 DB00751] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes ABCB1;CYP3A4 common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:1901529| ABCB1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0035556| intracellular signal transduction ADRA1A;SRC;BCR;LYN;CAMK2G GO:0006805| xenobiotic metabolic process CYP3A4;CYP2B6;CYP2D6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK;ADRA2A GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006706| steroid catabolic process CYP3A4 GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0042493| response to drug ABCB1;SRC;ADRA1A;HTR2A;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2B6;CYP2C8 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;CYP2D6;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0016032| viral reproduction HCK;SRC;LYN;HTR2A GO:0006954| inflammatory response HCK;HRH1;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0045332| phospholipid translocation ABCB1 GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2C8;CYP2D6 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0030168| platelet activation SRC;ADRA2A;LYN GO:0006810| transport ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ABL1;HTR2A GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction HTR7;MAP2K1;ADRA1A;SRC;BCR;ADRA2A;HRH1;HRH2;LYN;HTR2A GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP2D6;CYP2C8 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0002933| CYP2C8;CYP3A4 GO:0006915| apoptotic process ABL1;ADRA1A GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;ADRA1A;HTR2A GO:0055085| transmembrane transport ABCB1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A;SRC GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 5707:[DB06616 DB01537] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01537|4-Bromo-2,5-dimethoxyphenethylamine HTR2C;HTR2A common genes common pathways GO:0042493| response to drug LYN;HTR2A;SRC;ABCB1;HTR2C GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;HTR2C;MAP2K1;SRC;MAP2K2;HTR2A GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0007165| signal transduction HTR2C;MAP2K1;SRC;BCR;LYN;HTR2A 5708:[DB06616 DB03666] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03666|3'-Azido-3'-Deoxythymidine-5'-Monophosphate DTYMK;tmk common genes common pathways GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;DTYMK;CDK2;LYN;CAMK2G;MAP3K2 GO:0007049| cell cycle SRC;DTYMK;CDK2 GO:0008283| cell proliferation DTYMK;SRC 5709:[DB06616 DB00621] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation SRC;AR GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;AR GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0006810| transport ABCB1;AR GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;AR;MAP3K2;CDK2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0008284| positive regulation of cell proliferation AR;HCK;LYN;CDK2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0051259| protein oligomerization AR;CAMK2G 5710:[DB06616 DB08972] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08972|Flumequine CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug SRC;ABCB1;CYP1A2;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 5711:[DB06616 DB00765] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00765|Metyrosine TH common genes common pathways GO:0043434| response to peptide hormone stimulus TH;LYN GO:0014070| response to organic cyclic compound TH;LYN GO:0007507| heart development TH;MAP2K1 GO:0032496| response to lipopolysaccharide TH;BCR GO:0051602| response to electrical stimulus SRC;TH GO:0031667| response to nutrient levels TH;SRC GO:0042493| response to drug LYN;TH;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;TH;CYP2C8 5712:[DB06616 DB05824] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05824|CNS-5161 GRIN1 common genes common pathways GO:0048013| ephrin receptor signaling pathway LYN;GRIN1;SRC GO:0065009| regulation of molecular function GRIN1;CAMK2G GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;GRIN1;CAMK2G GO:0006816| calcium ion transport GRIN1;CAMK2G GO:0043065| positive regulation of apoptotic process GRIN1;SRC;ABL1 5713:[DB06616 DB03988] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ADCYAP1;ABL1;SRC;MAP2K2;MAP2K1 GO:0031175| neuron projection development ADCYAP1;LYN GO:0010628| positive regulation of gene expression MAP2K1;SRC;ADCYAP1 GO:0007204| elevation of cytosolic calcium ion concentration ADCYAP1;ABL1 GO:0043547| positive regulation of GTPase activity BCR;ADCYAP1 GO:0010976| positive regulation of neuron projection development LYN;ADCYAP1 GO:0001932| regulation of protein phosphorylation LYN;ADCYAP1;MAP2K1 GO:0007399| nervous system development ADCYAP1;CAMK2G GO:0030073| insulin secretion CAMK2G;ADCYAP1 GO:0008284| positive regulation of cell proliferation ADCYAP1;LYN;CDK2;HCK 5714:[DB06616 DB00805] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0006260| DNA replication ACHE;CDK2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0016032| viral reproduction HTR2A;LYN;HCK;SRC GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;HTR2B GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6;CYP2C8 GO:0042493| response to drug SLC6A4;HTR2B;HTR2C;DRD1;DRD2;SRC;ABCB1;LYN;HTR2A GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0007399| nervous system development ACHE;CHRM1;CAMK2G GO:0007507| heart development MAP2K1;HTR2B GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0043066| negative regulation of apoptotic process HTR2B;SRC;HCK GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0035556| intracellular signal transduction BCR;DRD2;SRC;CAMK2G;LYN GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HTR2A;LYN;CDK2;CHRM1;HCK;HTR2B GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0048678| response to axon injury LYN;DRD2 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;HTR2B GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0001932| regulation of protein phosphorylation DRD1;MAP2K1;LYN GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0006464| protein modification process ABL1;CHRM1 GO:0010033| response to organic substance SLC6A4;CDK2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC;HTR2B GO:0010628| positive regulation of gene expression SLC6A4;DRD1;SRC;MAP2K1 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;DRD2;SRC;MAP2K2;ABL1;HTR2B;HTR2C;HTR2A GO:0009636| response to toxin DRD2;SLC6A4;LYN GO:0008283| cell proliferation CHRM1;ACHE;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0030900| forebrain development SRC;DRD2 GO:1903351| DRD1;ABL1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction MAP2K1;BCR;DRD2;SRC;DRD1;HTR2C;HTR2B;HTR2A;LYN;CHRM1 GO:0007420| brain development SLC6A4;BCR GO:0050715| positive regulation of cytokine secretion SRC;HTR2B GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0016310| phosphorylation HTR2B;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;MAP3K2 5715:[DB06616 DB11793] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways GO:1900182| PARP1;SRC GO:0032869| cellular response to insulin stimulus PARP1;SRC GO:0006915| apoptotic process ABL1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PARP1 GO:0006281| DNA repair CDK2;PARP2;PARP1;ABL1 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;PARP1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:1901216| ABL1;PARP1 5716:[DB06616 DB03316] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;TGFB3;MAP3K2 GO:0001782| B cell homeostasis LYN;TNFSF13B GO:0006897| endocytosis ABL1;EPN1 GO:0002576| platelet degranulation LYN;TGFB3 GO:0043065| positive regulation of apoptotic process TGFB3;SRC;ABL1 GO:0008284| positive regulation of cell proliferation TNFSF13B;HCK;LYN;CDK2 GO:0042981| regulation of apoptotic process TGFB3;MAP3K2;MAP2K2;MAP2K1 GO:0051496| positive regulation of stress fiber assembly TGFB3;ABL1 GO:0008283| cell proliferation TNFSF13B;SRC GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TGFB3;MAP3K2 GO:0007179| transforming growth factor beta receptor signaling pathway TGFB3;SRC GO:0008285| negative regulation of cell proliferation LYN;TGFB3;MAP2K1 GO:0031295| T cell costimulation LYN;TNFSF13B;SRC GO:0002376| immune system process TNFSF13B;SRC;HCK;LYN GO:0007165| signal transduction MAP2K1;BCR;TNFSF13B;SRC;LYN 5717:[DB06616 DB06185] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06185|Forodesine PNP common genes common pathways GO:0042493| response to drug LYN;PNP;SRC;ABCB1 5718:[DB06616 DB01445] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01445|Bufotenine MAOA;MAOB common genes common pathways GO:0009636| response to toxin MAOB;LYN GO:0042493| response to drug SRC;ABCB1;LYN;MAOB GO:0055114| oxidation-reduction process MAOB;MAOA;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide MAOB;BCR 5719:[DB06616 DB00374] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0010628| positive regulation of gene expression PPARD;MAP2K1;SRC GO:0010033| response to organic substance CDK2;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;SRC GO:0007596| blood coagulation LYN;P2RY12 GO:0008283| cell proliferation SRC;PPARD GO:0006915| apoptotic process ABL1;PPARD GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0065009| regulation of molecular function CAMK2G;PTGIR;P2RY12 GO:0007165| signal transduction PTGIR;LYN;SRC;BCR;MAP2K1;P2RY12 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0030168| platelet activation LYN;P2RY12;SRC GO:0030154| cell differentiation HCK;PPARD;CAMK2G GO:0071456| cellular response to hypoxia SRC;PPARD GO:0050728| negative regulation of inflammatory response PPARD;BCR GO:0051924| regulation of calcium ion transport P2RY12;CAMK2G GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;PPARD;MAP3K2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2C9 GO:0006355| regulation of transcription, DNA-dependent PPARD;ABL1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;HCK;PPARD GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PPARD GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;PPARD GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARD GO:0007507| heart development MAP2K1;PPARD GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042127| regulation of cell proliferation PPARD;ABL1;SRC GO:0032496| response to lipopolysaccharide BCR;PTGIR GO:0042737| drug catabolic process CYP2C9;CYP3A4 5720:[DB06616 DB08445] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion DPP4;ABL1;SRC;HCK GO:0008284| positive regulation of cell proliferation HCK;DPP4;CDK2;LYN 5721:[DB06616 DB05875] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;BCHE;MAP2K1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;HCK GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process PTGS2;CYP19A1;CYP3A4;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0042493| response to drug LYN;BCHE;PTGS2;SRC;ABCB1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0008284| positive regulation of cell proliferation CDK2;LYN;PTGS2;HCK GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0060065| uterus development CYP19A1;SRC GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS2 5722:[DB06616 DB06989] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06989|{4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways GO:0006470| protein dephosphorylation PTPRB;CAMK2G 5723:[DB06616 DB04880] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04880|Enoximone PDE3A common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;PDE3A GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PDE3A GO:0043066| negative regulation of apoptotic process SRC;HCK;PDE3A GO:0006629| lipid metabolic process PDE3A;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;BCR;PDE3A;LYN 5724:[DB06616 DB12007] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12007|Isoflavone PPARA;PPARG common genes common pathways GO:0007165| signal transduction PPARG;LYN;SRC;BCR;MAP2K1 GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0014070| response to organic cyclic compound LYN;PPARG GO:0032868| response to insulin stimulus LYN;PPARA GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA GO:0007507| heart development MAP2K1;PPARA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PPARA;CDK2 GO:0045087| innate immune response ABL1;SRC;HCK;PPARG;LYN GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;PPARA;PPARG;CDK2;MAP3K2 GO:0042493| response to drug ABCB1;SRC;LYN;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA;ABL1 5725:[DB06616 DB08801] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08801|Dimetindene HRH1;CHRM2 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;CHRM2;LYN;HRH1 GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0006954| inflammatory response LYN;HRH1;HCK GO:0007399| nervous system development CHRM2;CAMK2G GO:0009615| response to virus SRC;CHRM2 5726:[DB06616 DB00382] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00382|Tacrine ACHE;BCHE;CES1;CYP1A2;ABCB1 common genes ABCB1 common pathways GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009636| response to toxin CES1;LYN GO:0008283| cell proliferation ACHE;SRC GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ABL1;HCK;SRC;ACHE GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006260| DNA replication ACHE;CDK2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2;BCHE GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 5727:[DB06616 DB06932] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;PDPK1 GO:0016477| cell migration SRC;PDPK1 GO:0038095| PDPK1;LYN GO:0046777| protein autophosphorylation PDPK1;LYN;CAMK2G;HCK;SRC;BCR;ABL1 GO:0030168| platelet activation LYN;PDPK1;SRC GO:0006468| protein phosphorylation MAP3K2;CAMK2G;PDPK1;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0032869| cellular response to insulin stimulus SRC;PDPK1 GO:0016310| phosphorylation LYN;CDK2;PDPK1;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0031295| T cell costimulation PDPK1;LYN;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0007173| epidermal growth factor receptor signaling pathway PDPK1;SRC;ABL1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;ABL1 GO:0030036| actin cytoskeleton organization PDPK1;BCR;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;PDPK1 GO:0032148| activation of protein kinase B activity SRC;PDPK1 GO:0035556| intracellular signal transduction CAMK2G;LYN;PDPK1;SRC;BCR GO:0043304| regulation of mast cell degranulation LYN;PDPK1 GO:0018105| peptidyl-serine phosphorylation CAMK2G;PDPK1;CDK2;SRC 5728:[DB06616 DB07724] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07724|Indeglitazar NCOA1;PPARA;PPARD;PPARG common genes common pathways GO:0030154| cell differentiation CAMK2G;PPARD;HCK GO:0071456| cellular response to hypoxia SRC;PPARD GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0007165| signal transduction PPARG;LYN;BCR;SRC;MAP2K1 GO:0032868| response to insulin stimulus PPARA;LYN GO:0006915| apoptotic process ABL1;PPARD GO:0008283| cell proliferation SRC;PPARD GO:0014070| response to organic cyclic compound PPARG;LYN GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1 GO:0010033| response to organic substance PPARD;PPARG;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD;SRC GO:0010628| positive regulation of gene expression PPARD;SRC;MAP2K1 GO:0042127| regulation of cell proliferation PPARD;ABL1;SRC GO:0045087| innate immune response HCK;SRC;ABL1;LYN;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;PPARA;PPARG;CDK2 GO:0007507| heart development MAP2K1;PPARD;PPARA;PPARG GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4;PPARD GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG;NCOA1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PPARD GO:0008284| positive regulation of cell proliferation HCK;PPARD;CDK2;LYN GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043066| negative regulation of apoptotic process PPARD;HCK;SRC GO:0042493| response to drug ABCB1;SRC;PPARG;LYN GO:0006355| regulation of transcription, DNA-dependent PPARD;NCOA1;PPARG;PPARA;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;MAP3K2;NCOA1;CDK2;PPARG;PPARA;MAP2K1;MAP2K2;SRC GO:0050728| negative regulation of inflammatory response PPARD;PPARA;BCR 5729:[DB06616 DB01762] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways GO:0055085| transmembrane transport SLC16A3;SLC16A7;SLC16A1;ABCB1;SLC5A8 GO:0006915| apoptotic process SLC5A8;ABL1 GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0050900| leukocyte migration SRC;SLC16A1;LYN;SLC16A3 5730:[DB06616 DB02089] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02089|CP-526423 PYGL common genes common pathways 5731:[DB06616 DB00527] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A;CALM1;SCN10A GO:0038095| LYN;CALM1 GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;CALM1 GO:0002576| platelet degranulation CALM1;LYN GO:0042493| response to drug SRC;ABCB1;BCHE;LYN GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CALM1;CAMK2G 5732:[DB06616 DB00253] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0051301| cell division NR3C1;CDK2 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0007165| signal transduction NR3C1;LYN;MAP2K1;BCR;SRC GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0006915| apoptotic process NR3C1;ABL1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 5733:[DB06616 DB05386] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0065009| regulation of molecular function CSF2RA;CAMK2G GO:0042493| response to drug BCHE;LYN;SRC;ABCB1 GO:0019221| cytokine-mediated signaling pathway CSF2RA;HCK GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CSF2RA;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;CSF2RA;BCR;MAP2K2;HCK;MAP2K1 5734:[DB06616 DB03430] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03430|(2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile LCTL common genes common pathways 5735:[DB06616 DB07294] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07294|3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid RARG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;RARG GO:0060324| face development MAP2K1;RARG GO:0071300| cellular response to retinoic acid RARG;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;RARG GO:0043065| positive regulation of apoptotic process SRC;RARG;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;RARG;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARG GO:0010628| positive regulation of gene expression SRC;MAP2K1;RARG GO:0008285| negative regulation of cell proliferation MAP2K1;RARG;LYN GO:0001843| neural tube closure RARG;ABL1 5736:[DB06616 DB05429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05429|CAT-213 CCL11 common genes common pathways GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;CCL11 GO:0043547| positive regulation of GTPase activity CCL11;BCR GO:0030335| positive regulation of cell migration CCL11;LYN GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;CCL11;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0060444| branching involved in mammary gland duct morphogenesis SRC;CCL11 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;CCL11 GO:0009615| response to virus CCL11;SRC GO:0006935| chemotaxis MAP2K1;CCL11 GO:0007155| cell adhesion CCL11;ABL1;SRC;HCK GO:0008360| regulation of cell shape HCK;CCL11 GO:0030838| positive regulation of actin filament polymerization CCL11;HCK GO:0070371| ERK1 and ERK2 cascade CCL11;MAP2K2;MAP2K1 GO:0006954| inflammatory response CCL11;HCK;LYN 5737:[DB06616 DB07689] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07689|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHRS4L1;CYP3A4 5738:[DB06616 DB06127] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06127|Bisegliptin DPP4 common genes common pathways GO:0031295| T cell costimulation LYN;DPP4;SRC GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 5739:[DB06616 DB07574] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07574|2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE STMN4;TUBB2B;TUBA1A;TUBA1C;TUBA1B common genes common pathways GO:0031175| neuron projection development STMN4;LYN GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2;TUBA1A GO:0051301| cell division TUBA1C;TUBA1B;CDK2;TUBA1A GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBA1A;CDK2 GO:0007399| nervous system development CAMK2G;TUBB2B 5740:[DB06616 DB09051] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09051|Elosulfase alfa GALNS common genes common pathways 5741:[DB06616 DB06781] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06781|Difluprednate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;BCR;SRC;NR3C1;LYN GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0006915| apoptotic process NR3C1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0051301| cell division CDK2;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 5742:[DB06616 DB01615] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01615|Aceprometazine HRH1 common genes common pathways GO:0007165| signal transduction LYN;HRH1;MAP2K1;SRC;BCR GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 5743:[DB06616 DB00939] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance CDK2;PTGS2 GO:0055085| transmembrane transport ABCB1;KCNQ2;SLCO1C1;SLC22A6;KCNQ3 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0006813| potassium ion transport KCNQ2;CDK2;KCNQ3 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS2;LYN;ALOX5;PTGS1;HCK GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0042493| response to drug SRC;ABCB1;LYN;PTGS2 GO:0007399| nervous system development KCNQ2;CAMK2G GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1;ABL1 GO:0032496| response to lipopolysaccharide BCR;PTGS2 5744:[DB06616 DB02800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways 5745:[DB06616 DB04931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04931|Afamelanotide MC1R common genes common pathways GO:0007275| multicellular organismal development MC1R;CAMK2G;CDK2 GO:0035556| intracellular signal transduction SRC;BCR;LYN;MC1R;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade MC1R;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;MC1R;LYN 5746:[DB06616 DB09151] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09151|Flutemetamol (18F) APP common genes common pathways GO:0006979| response to oxidative stress APP;ABL1 GO:0030900| forebrain development APP;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP GO:0006468| protein phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;APP;MAP3K2;CAMK2G;CDK2;LYN GO:1900272| ABL1;APP GO:0010628| positive regulation of gene expression SRC;MAP2K1;APP GO:0008285| negative regulation of cell proliferation MAP2K1;APP;LYN GO:0031175| neuron projection development APP;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;ABL1;MAP2K1;SRC;MAP2K2 GO:0000187| activation of MAPK activity APP;MAP3K2;MAP2K2;MAP2K1 GO:0006915| apoptotic process ABL1;APP GO:0043065| positive regulation of apoptotic process SRC;ABL1;APP GO:0002576| platelet degranulation APP;LYN GO:0042327| positive regulation of phosphorylation LYN;APP GO:0006897| endocytosis ABL1;APP GO:0007399| nervous system development CAMK2G;APP GO:0007155| cell adhesion ABL1;SRC;HCK;APP GO:0045087| innate immune response APP;LYN;HCK;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0045931| positive regulation of mitotic cell cycle ABL1;APP GO:0043393| regulation of protein binding APP;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;LYN;SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;APP GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;APP GO:1901216| APP;ABL1 GO:0050885| neuromuscular process controlling balance BCR;ABL1;APP GO:0001934| positive regulation of protein phosphorylation LYN;APP;ABL1 5747:[DB06616 DB05945] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways GO:0007165| signal transduction SRC;BCR;ANTXR1;MAP2K1;LYN GO:0034446| substrate adhesion-dependent cell spreading SRC;ANTXR1;ABL1 5748:[DB06616 DB07815] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways 5749:[DB06616 DB11131] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11131|Capsicum oleoresin TRPV1 common genes common pathways GO:0055085| transmembrane transport ABCB1;TRPV1 GO:0065009| regulation of molecular function CAMK2G;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TRPV1 GO:0006810| transport TRPV1;ABCB1 GO:0043434| response to peptide hormone stimulus LYN;TRPV1 GO:0034605| cellular response to heat TRPV1;LYN GO:0006954| inflammatory response LYN;HCK;TRPV1 GO:0006816| calcium ion transport TRPV1;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;CDK2 GO:0006629| lipid metabolic process TRPV1;CYP3A4 GO:0043065| positive regulation of apoptotic process SRC;TRPV1;ABL1 5750:[DB06616 DB03478] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways GO:0031667| response to nutrient levels SIRT5;SRC GO:2000378| negative regulation of reactive oxygen species metabolic process SIRT5;BCR 5751:[DB06616 DB01481] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01481|1-Testosterone AR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;SRC;MAP2K2;MAP2K1;AR GO:0051259| protein oligomerization AR;CAMK2G GO:0008284| positive regulation of cell proliferation AR;HCK;CDK2;LYN GO:0042327| positive regulation of phosphorylation LYN;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction AR;BCR;SRC;MAP2K1;LYN 5752:[DB06616 DB01892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8 GO:0042493| response to drug LYN;SRC;ABCB1;ABCC2 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1I2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGS1;ALOX5 GO:0006954| inflammatory response LYN;ALOX5;PTGS1;HCK GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:0006805| xenobiotic metabolic process CYP3A4;NR1I2;CYP2C8;PTGS1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABCC2;ABL1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLCO1B1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;NR1I2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;SRC GO:0008202| steroid metabolic process CYP3A4;NR1I2;CYP2C8 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0006810| transport ABCC2;ABCB1 GO:0006979| response to oxidative stress PTGS1;ABCC2;ABL1 GO:0007165| signal transduction BCR;SRC;MAP2K1;NR1I2;LYN 5753:[DB06616 DB06823] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06823|Tiopronin MPO common genes common pathways GO:0006979| response to oxidative stress MPO;ABL1 GO:0055114| oxidation-reduction process CYP2C8;MPO;CYP3A4 GO:0032496| response to lipopolysaccharide MPO;BCR GO:0043066| negative regulation of apoptotic process HCK;MPO;SRC GO:0009612| response to mechanical stimulus SRC;MPO 5754:[DB06616 DB00369] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways GO:0006935| chemotaxis MAP2K1;TYMP GO:0007275| multicellular organismal development TYMP;CDK2;CAMK2G GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0030154| cell differentiation TYMP;HCK;CAMK2G 5755:[DB06616 DB01141] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01141|Micafungin COMT;ARSA common genes common pathways GO:0042493| response to drug ABCB1;SRC;COMT;LYN GO:0032496| response to lipopolysaccharide BCR;COMT GO:0014070| response to organic cyclic compound COMT;LYN 5756:[DB06616 DB07183] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07183|N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide KDR common genes common pathways GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0016032| viral reproduction LYN;SRC;KDR;HCK GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;KDR GO:0010629| negative regulation of gene expression KDR;MAP2K1;MAP2K2 GO:0038083| KDR;HCK;SRC;ABL1;LYN GO:0008360| regulation of cell shape KDR;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;KDR GO:0043066| negative regulation of apoptotic process SRC;KDR;HCK GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0007275| multicellular organismal development CDK2;CAMK2G;KDR GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR;LYN GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;KDR;SRC;BCR;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2;SRC;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0030154| cell differentiation KDR;HCK;CAMK2G GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;KDR;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0030335| positive regulation of cell migration LYN;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;KDR 5757:[DB06616 DB06804] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0008284| positive regulation of cell proliferation HCK;PTGS2;LYN;CDK2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042493| response to drug ABCB1;SRC;PTGS2;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 5758:[DB06616 DB08678] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08678|(4-ETHYLPHENYL)SULFAMIC ACID PTPRB common genes common pathways GO:0006470| protein dephosphorylation CAMK2G;PTPRB 5759:[DB06616 DB00826] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00826|Natamycin CYP3A4 common genes CYP3A4 common pathways GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 5760:[DB06616 DB04820] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0032496| response to lipopolysaccharide BCR;COMT;MAOB GO:0042493| response to drug LYN;COMT;MAOB;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOB;MAOA GO:0009636| response to toxin MAOB;LYN GO:0014070| response to organic cyclic compound COMT;LYN 5761:[DB06616 DB06515] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06515|Resiniferatoxin TRPV1 common genes common pathways GO:0006816| calcium ion transport CAMK2G;TRPV1 GO:0006954| inflammatory response LYN;HCK;TRPV1 GO:0006629| lipid metabolic process TRPV1;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TRPV1 GO:0043065| positive regulation of apoptotic process TRPV1;SRC;ABL1 GO:0055085| transmembrane transport TRPV1;ABCB1 GO:0065009| regulation of molecular function CAMK2G;TRPV1 GO:0006810| transport TRPV1;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;ABL1 GO:0043434| response to peptide hormone stimulus LYN;TRPV1 GO:0034605| cellular response to heat LYN;TRPV1 5762:[DB06616 DB07182] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 5763:[DB06616 DB02008] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0071456| cellular response to hypoxia SRC;PCK1 GO:0032869| cellular response to insulin stimulus SRC;PCK1 GO:0032868| response to insulin stimulus LYN;PCK1 GO:0071300| cellular response to retinoic acid PCK1;LYN GO:0006629| lipid metabolic process PCK1;CYP3A4 GO:0032496| response to lipopolysaccharide PCK1;BCR 5764:[DB06616 DB07537] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07537|N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;KDR;MAP2K1;MAP2K2;SRC GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;KDR;HCK;BCR;SRC GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;KDR;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0030154| cell differentiation CAMK2G;HCK;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;KDR GO:0030335| positive regulation of cell migration LYN;KDR GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0001934| positive regulation of protein phosphorylation KDR;ABL1;LYN GO:0010629| negative regulation of gene expression MAP2K1;KDR;MAP2K2 GO:0038083| ABL1;HCK;KDR;SRC;LYN GO:0016032| viral reproduction SRC;HCK;KDR;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;KDR;ABL1;LYN GO:0007275| multicellular organismal development KDR;CAMK2G;CDK2 GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0008360| regulation of cell shape KDR;HCK GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process HCK;KDR;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;KDR;HCK 5765:[DB06616 DB07486] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07486|3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline ITGAL common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ITGAL GO:0098609| SRC;ITGAL GO:0007229| integrin-mediated signaling pathway ITGAL;HCK;SRC;ABL1 GO:0006928| cellular component movement MAP2K1;ITGAL GO:0007155| cell adhesion HCK;SRC;ABL1;ITGAL GO:0006954| inflammatory response HCK;ITGAL;LYN GO:0006909| phagocytosis ITGAL;ABL1;HCK GO:0050900| leukocyte migration SRC;ITGAL;LYN 5766:[DB06616 DB13346] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response PTGS1;HCK;PTGS2;LYN GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0006914| autophagy ABL1;HDAC6 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0006355| regulation of transcription, DNA-dependent HDAC6;HDAC10;ABL1 GO:0014003| oligodendrocyte development LYN;HDAC10 GO:0042493| response to drug ABCB1;SRC;PTGS2;LYN GO:0010506| regulation of autophagy HDAC6;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;HDAC10 GO:0048668| collateral sprouting HDAC6;ABL1 GO:0010634| positive regulation of epithelial cell migration HDAC6;SRC GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:0070301| cellular response to hydrogen peroxide ABL1;HDAC6 GO:0045892| negative regulation of transcription, DNA-dependent SRC;HDAC10;HDAC6 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance CDK2;HDAC6;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0009636| response to toxin HDAC6;LYN GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 5767:[DB06616 DB08129] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08129|(1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol PNMT common genes common pathways 5768:[DB06616 DB00099] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00099|Filgrastim CSF3R;ELANE common genes common pathways GO:0032496| response to lipopolysaccharide BCR;ELANE GO:0007155| cell adhesion CSF3R;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ELANE GO:0050900| leukocyte migration ELANE;SRC;LYN GO:0006909| phagocytosis ABL1;ELANE;HCK GO:0019221| cytokine-mediated signaling pathway HCK;CSF3R GO:0050728| negative regulation of inflammatory response BCR;ELANE GO:0007165| signal transduction LYN;CSF3R;BCR;SRC;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;ELANE 5769:[DB06616 DB04326] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04326|Dihydroxyacetone phosphate ALDOA;TPI1;ALDOB;fucA common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;TPI1 GO:0002576| platelet degranulation ALDOA;LYN GO:0008360| regulation of cell shape HCK;ALDOA 5770:[DB06616 DB02216] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02216|S-Methylcysteine CTSD;MGMT;FABP1 common genes common pathways GO:0009636| response to toxin LYN;MGMT GO:0014070| response to organic cyclic compound LYN;MGMT GO:0070301| cellular response to hydrogen peroxide ABL1;FABP1 GO:0071456| cellular response to hypoxia SRC;FABP1 GO:0006914| autophagy ABL1;CTSD GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process FABP1;SRC GO:0042493| response to drug MGMT;LYN;ABCB1;SRC GO:0034599| cellular response to oxidative stress ABL1;MGMT GO:0006974| response to DNA damage stimulus LYN;CDK2;MGMT;ABL1 GO:0006281| DNA repair MGMT;CDK2;ABL1 GO:0043066| negative regulation of apoptotic process MGMT;FABP1;HCK;SRC 5771:[DB06616 DB03546] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways GO:0010033| response to organic substance CDK2;GART 5772:[DB06616 DB00325] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;BCR GO:0009615| response to virus SRC;CYP1A1 GO:0035556| intracellular signal transduction LYN;CAMK2G;NPR1;SRC;BCR GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A1 GO:0043114| regulation of vascular permeability BCR;SRC;NPR1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A1 GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;BCR;MAP2K2;SRC;NPR1;MAP2K1;HCK GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A1;CYP2C8 GO:0008283| cell proliferation CYP1A1;SRC GO:0002933| CYP2C8;CYP3A4;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;LYN GO:0009636| response to toxin LYN;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance CYP1A1;CDK2 5773:[DB06616 DB00287] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00287|Travoprost PTGFR common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;PTGFR GO:0007165| signal transduction MAP2K1;BCR;SRC;PTGFR;LYN GO:0032496| response to lipopolysaccharide PTGFR;BCR GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGFR GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;PTGFR 5774:[DB06616 DB01378] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01378|Magnesium cation ATP1A1 common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;ATP1A1 GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 GO:0006813| potassium ion transport CDK2;ATP1A1 5775:[DB06616 DB13931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0051894| positive regulation of focal adhesion assembly ROCK1;ABL1 GO:0035556| intracellular signal transduction SRC;BCR;ROCK1;ROCK2;CAMK2G;LYN GO:2000145| regulation of cell motility ROCK2;ROCK1;ABL1 GO:0030155| regulation of cell adhesion ROCK1;ABL1;ROCK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway ROCK1;SRC;ROCK2 GO:0051298| centrosome duplication ROCK2;CDK2 GO:0010506| regulation of autophagy ROCK1;ABL1 GO:0050900| leukocyte migration LYN;SRC;ROCK1 GO:0001934| positive regulation of protein phosphorylation LYN;ROCK2;ABL1 GO:0030036| actin cytoskeleton organization ROCK2;ROCK1;ABL1;BCR GO:0010595| positive regulation of endothelial cell migration ABL1;ROCK2 GO:0016310| phosphorylation ABL1;ROCK1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;ROCK2;MAP3K2 GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ROCK1;ABL1;MAP3K2;LYN;CDK2;CAMK2G;ROCK2 GO:0032956| regulation of actin cytoskeleton organization ROCK2;ROCK1;ABL1 GO:0007165| signal transduction LYN;ROCK1;SRC;BCR;MAP2K1 GO:0031175| neuron projection development ROCK1;LYN GO:0006915| apoptotic process ROCK1;ABL1 GO:0010628| positive regulation of gene expression ROCK2;SRC;MAP2K1;ROCK1 GO:0048013| ephrin receptor signaling pathway SRC;ROCK1;ROCK2;LYN 5776:[DB06616 DB04837] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04837|Clofedanol HRH1 common genes common pathways GO:0007165| signal transduction LYN;HRH1;SRC;BCR;MAP2K1 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0006954| inflammatory response LYN;HRH1;HCK 5777:[DB06616 DB05161] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0050728| negative regulation of inflammatory response ELANE;BCR GO:0050900| leukocyte migration ELANE;SRC;LYN GO:0055114| oxidation-reduction process CYP2C8;MPO;CYP3A4 GO:0006909| phagocytosis ELANE;HCK;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ELANE;CDK2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PRTN3 GO:0009612| response to mechanical stimulus SRC;MPO GO:0043066| negative regulation of apoptotic process HCK;MPO;SRC GO:0032496| response to lipopolysaccharide ELANE;MPO;BCR GO:0043406| positive regulation of MAP kinase activity ELANE;SRC GO:0007596| blood coagulation LYN;PRTN3 GO:0006979| response to oxidative stress ABL1;MPO GO:0043547| positive regulation of GTPase activity BCR;PRTN3 5778:[DB06616 DB07692] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07692|1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine PKM common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PKM GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;PKM;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0010033| response to organic substance PKM;CDK2 GO:0032868| response to insulin stimulus PKM;LYN 5779:[DB06616 DB00179] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2J2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2J2;CYP2C8 GO:0006954| inflammatory response ALOX5;HCK;LYN GO:0055114| oxidation-reduction process ALOX5;CYP2C8;CYP2J2;CYP3A4 5780:[DB06616 DB08950] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08950|Indoramin ADRA1A common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A;SRC;LYN GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;ADRA1A;BCR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;ADRA1A;MAP2K2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ABL1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction LYN;BCR;SRC;ADRA1A;MAP2K1 5781:[DB06616 DB07879] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0006954| inflammatory response HCK;HDAC4;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;HDAC4;CDK2;MAP2K2;SRC;MAP2K1 GO:0042493| response to drug HDAC4;LYN;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;HDAC4 GO:0008284| positive regulation of cell proliferation HCK;HDAC4;CDK2;LYN GO:0071260| cellular response to mechanical stimulus MAP3K2;HDAC4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC4;CDK2 GO:0007399| nervous system development CAMK2G;HDAC4 GO:0043393| regulation of protein binding SRC;HDAC4 GO:0008285| negative regulation of cell proliferation MAP2K1;HDAC4;LYN GO:0014911| positive regulation of smooth muscle cell migration SRC;HDAC4 GO:0045892| negative regulation of transcription, DNA-dependent HDAC4;SRC GO:0070555| response to interleukin-1 HDAC4;SRC 5782:[DB06616 DB07453] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LYN;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 5783:[DB06616 DB02179] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5784:[DB06616 DB03747] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways GO:0008360| regulation of cell shape HCK;HEXB GO:0050885| neuromuscular process controlling balance ABL1;HEXB;BCR GO:0048477| oogenesis HEXB;SRC 5785:[DB06616 DB06819] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 5786:[DB06616 DB07668] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways 5787:[DB06616 DB07383] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways 5788:[DB06616 DB02611] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02611|Balanol Analog 1 PRKACA common genes common pathways GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;PRKACA;MAP3K2 GO:0034605| cellular response to heat LYN;PRKACA GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;PRKACA;CDK2;LYN;CAMK2G GO:0000086| G2/M transition of mitotic cell cycle PRKACA;CDK2;ABCB1 GO:0007596| blood coagulation PRKACA;LYN GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PRKACA;SRC GO:0043393| regulation of protein binding PRKACA;SRC GO:0018105| peptidyl-serine phosphorylation PRKACA;CDK2;CAMK2G;SRC GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2 5789:[DB06616 DB05304] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05304|WX-G250 CA9;IL2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;IL2 GO:0002376| immune system process LYN;IL2;SRC;HCK GO:0065009| regulation of molecular function IL2;CAMK2G GO:0001933| negative regulation of protein phosphorylation LYN;IL2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL2;LYN GO:0008284| positive regulation of cell proliferation HCK;IL2;CDK2;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;IL2 GO:0007155| cell adhesion HCK;SRC;IL2;ABL1 GO:0042493| response to drug LYN;CA9;ABCB1;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;IL2;LYN GO:0050728| negative regulation of inflammatory response BCR;IL2 GO:0000165| MAPKKK cascade IL2;MAP2K1;MAP2K2;CAMK2G GO:0002250| adaptive immune response IL2;LYN 5790:[DB06616 DB04885] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04885|Cilansetron HTR3A common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;HTR3A 5791:[DB06616 DB00419] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00419|Miglustat UGCG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;UGCG 5792:[DB06616 DB14528] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14528|Chromium gluconate CYB5A;TF common genes common pathways GO:0002576| platelet degranulation TF;LYN GO:0055114| oxidation-reduction process CYB5A;CYP3A4;CYP2C8 5793:[DB06616 DB01763] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways GO:0055114| oxidation-reduction process NNT;CYP2C8;CYP3A4 5794:[DB06616 DB00155] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0032868| response to insulin stimulus LYN;OTC GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;DDAH1;LYN GO:0006464| protein modification process PADI4;ABL1 GO:0002376| immune system process HCK;SRC;LYN;PADI4 GO:0055114| oxidation-reduction process NOS2;CYP3A4;NOS1;NOS3;CYP2C8 GO:0031667| response to nutrient levels OTC;SRC GO:0045893| positive regulation of transcription, DNA-dependent NOS1;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0042493| response to drug OTC;SRC;ABCB1;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;NOS1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 GO:0006355| regulation of transcription, DNA-dependent ABL1;PADI4 GO:0043542| endothelial cell migration NOS3;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0045087| innate immune response PADI4;LYN;SRC;HCK;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;HCK;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;DDAH2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;PADI2 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;NOS2 5795:[DB06616 DB07096] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07096|6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE PARP1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:1901216| ABL1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 GO:0006281| DNA repair ABL1;PARP1;CDK2 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;PARP1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0006915| apoptotic process ABL1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:1900182| PARP1;SRC GO:0032869| cellular response to insulin stimulus PARP1;SRC 5796:[DB06616 DB07272] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07272|N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;HCK;MAPK8;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAPK8;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;MAPK8 GO:0007165| signal transduction MAPK8IP1;MAP2K1;SRC;BCR;LYN GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAPK8;MAP2K1 GO:0038095| LYN;MAPK8 GO:0010628| positive regulation of gene expression SRC;MAP2K1;MAPK8 GO:0034614| cellular response to reactive oxygen species MAPK8;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;MAPK8 GO:0043066| negative regulation of apoptotic process MAPK8;HCK;SRC;MAPK8IP1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;MAPK8 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;MAPK8;ABL1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;MAPK8;SRC GO:0006355| regulation of transcription, DNA-dependent MAPK8IP1;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MAPK8IP1;SRC 5797:[DB06616 DB01091] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01091|Butenafine SQLE common genes common pathways GO:0010033| response to organic substance SQLE;CDK2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;SQLE 5798:[DB06616 DB07003] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process NOS2;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation NOS2;SRC;ABL1 GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR 5799:[DB06616 DB01359] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR1A GO:0002576| platelet degranulation LYN;ORM1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0051385| response to mineralocorticoid stimulus HTR1B;SRC GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006954| inflammatory response ORM1;LYN;HCK GO:0042493| response to drug SRC;HTR1B;ABCB1;LYN GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0045453| bone resorption ADRB2;SRC GO:0007165| signal transduction HTR1A;LYN;ADRB2;BCR;ADRB1;HTR1B;SRC;MAP2K1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K2;SRC;MAP2K1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008283| cell proliferation SRC;HTR1A 5800:[DB06616 DB12340] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways GO:0042981| regulation of apoptotic process BCL2;MAP3K2;BAD;MAP2K1;MAP2K2;BCL2L2 GO:0071260| cellular response to mechanical stimulus BAD;MAP3K2 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;BCL2 GO:0008284| positive regulation of cell proliferation BCL2;LYN;CDK2;HCK GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;BCL2;SRC GO:0042542| response to hydrogen peroxide BAD;BCL2;SRC GO:0051726| regulation of cell cycle BCL2;ABL1;BCR;SRC GO:0043065| positive regulation of apoptotic process BAD;SRC;ABL1 GO:0043066| negative regulation of apoptotic process BCL2L2;HCK;SRC;BCL2 GO:0051902| negative regulation of mitochondrial depolarization SRC;BCL2 GO:0042493| response to drug LYN;BAD;BCL2;SRC;ABCB1 GO:0010506| regulation of autophagy BCL2;ABL1 GO:1901216| ABL1;BAD GO:0019221| cytokine-mediated signaling pathway HCK;BAD GO:0051924| regulation of calcium ion transport CAMK2G;BCL2 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2L2;BCL2 GO:0001782| B cell homeostasis BCL2;LYN GO:2000811| negative regulation of anoikis SRC;BCL2 GO:0071456| cellular response to hypoxia BCL2;BAD;SRC GO:0045930| negative regulation of mitotic cell cycle BCL2;ABL1 GO:0098609| BCL2;SRC GO:0009725| response to hormone stimulus LYN;BAD GO:0003014| renal system process BCL2;BCR GO:0030097| hemopoiesis BCL2;LYN GO:0048538| thymus development MAP2K1;ABL1;BCL2 GO:0048536| spleen development ABL1;BCL2 GO:0006979| response to oxidative stress ABL1;BCL2 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;BCL2;CAMK2G GO:0055085| transmembrane transport ABCB1;BCL2 GO:0042100| B cell proliferation BCL2;ABL1 GO:0006915| apoptotic process ABL1;BCL2L2;BCL2;BAD GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis BAD;BCL2;ABL1;BCL2L2 GO:0008283| cell proliferation SRC;BCL2;BAD GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;BCR GO:0014070| response to organic cyclic compound BAD;LYN GO:0009636| response to toxin LYN;BCL2 GO:0043200| response to amino acid stimulus BAD;LYN GO:0006470| protein dephosphorylation BCL2;CAMK2G GO:0014911| positive regulation of smooth muscle cell migration BCL2;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;BCL2;LYN GO:0010033| response to organic substance CDK2;BAD GO:0030336| negative regulation of cell migration BCR;BCL2 GO:0009791| post-embryonic development BCL2;ABL1 GO:0050853| B cell receptor signaling pathway LYN;BCL2;ABL1 5801:[DB06616 DB04606] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0007596| blood coagulation LYN;F7 GO:0014070| response to organic cyclic compound F7;LYN GO:0030335| positive regulation of cell migration LYN;F7 GO:0009725| response to hormone stimulus LYN;F7 GO:0031667| response to nutrient levels F7;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F7 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC 5802:[DB06616 DB00524] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00524|Metolazone SLC12A3 common genes common pathways GO:0006810| transport SLC12A3;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC12A3 5803:[DB06616 DB04890] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04890|Bepotastine HRH1 common genes common pathways GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;HRH1 5804:[DB06616 DB03661] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03661|Cysteinesulfonic Acid CTSL;def;GLIPR2;def;fabH;PTPN1;CDC25B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle CDK2;CDC25B;ABCB1 GO:0007257| activation of JUN kinase activity MAP3K2;PTPN1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GLIPR2;SRC;MAP2K2;MAP2K1;ABL1 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;PTPN1 GO:0070373| negative regulation of ERK1 and ERK2 cascade PTPN1;ABL1;LYN GO:0006470| protein dephosphorylation CDC25B;CAMK2G;PTPN1 GO:0043407| negative regulation of MAP kinase activity LYN;PTPN1 GO:0007049| cell cycle CDK2;CDC25B;SRC GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2;CDC25B GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1;PTPN1 GO:0030100| regulation of endocytosis ABL1;PTPN1 GO:0000278| mitotic cell cycle ABL1;CDC25B GO:0002250| adaptive immune response CTSL;LYN GO:0051301| cell division CDK2;CDC25B GO:0045931| positive regulation of mitotic cell cycle CDC25B;ABL1 GO:0010634| positive regulation of epithelial cell migration GLIPR2;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CDC25B 5805:[DB06616 DB07992] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0002576| platelet degranulation LYN;ALB 5806:[DB06616 DB03101] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03101|Ribose-1-Phosphate PNP common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;PNP 5807:[DB06616 DB08055] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0050853| B cell receptor signaling pathway LCK;ABL1;LYN GO:0006470| protein dephosphorylation LCK;CAMK2G GO:0016477| cell migration LCK;SRC GO:0050690| regulation of defense response to virus by virus LCK;HCK GO:0030097| hemopoiesis LCK;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LCK;LYN GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;LCK;HCK;MAP2K2;BCR;SRC;ABL1 GO:0031295| T cell costimulation SRC;LCK;LYN GO:0030168| platelet activation LYN;LCK;SRC GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;HCK;MAP2K1;LCK;SRC;MAP2K2;BCR;ABL1 GO:0016032| viral reproduction LYN;LCK;HCK;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;LCK GO:0038083| LYN;ABL1;SRC;HCK;LCK GO:0042493| response to drug LYN;ABCB1;SRC;LCK GO:0050900| leukocyte migration LYN;LCK;SRC GO:0045087| innate immune response LYN;LCK;HCK;SRC;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC;LCK GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;LCK;ABL1;LYN 5808:[DB06616 DB01776] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01776|M-Cresol INS common genes common pathways GO:0030335| positive regulation of cell migration LYN;INS GO:0050715| positive regulation of cytokine secretion SRC;INS GO:1900182| SRC;INS GO:0010628| positive regulation of gene expression SRC;MAP2K1;INS GO:0008284| positive regulation of cell proliferation LYN;CDK2;INS;HCK GO:0045597| positive regulation of cell differentiation MAP2K1;INS GO:0032148| activation of protein kinase B activity INS;SRC GO:0006355| regulation of transcription, DNA-dependent INS;ABL1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2;INS GO:0046628| positive regulation of insulin receptor signaling pathway INS;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INS GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation INS;ABL1;SRC;LYN GO:0031954| positive regulation of protein autophosphorylation SRC;INS 5809:[DB06616 DB09087] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09087|Potassium alum ALB common genes common pathways GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 5810:[DB06616 DB09121] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADCY5 GO:0007165| signal transduction ADCY1;MAP2K1;ADCY2;SRC;BCR;LYN GO:0035556| intracellular signal transduction ADCY2;SRC;BCR;ADCY1;ADCY5;CAMK2G;LYN GO:0042493| response to drug ABCB1;SRC;ADCY1;LYN GO:0050885| neuromuscular process controlling balance BCR;ABL1;ADCY5 5811:[DB06616 DB07342] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0042542| response to hydrogen peroxide SRC;HMOX1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;HMOX1 GO:0035556| intracellular signal transduction SRC;BCR;CAMK2G;HMOX1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;ABL1 GO:0055114| oxidation-reduction process HMOX1;CYP3A4;CYP2C8 GO:0006979| response to oxidative stress HMOX1;ABL1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HMOX1;HCK GO:0034605| cellular response to heat HMOX1;LYN GO:0071456| cellular response to hypoxia SRC;HMOX1 GO:0008285| negative regulation of cell proliferation HMOX1;LYN;MAP2K1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;HMOX1 GO:0006915| apoptotic process ABL1;HMOX1 5812:[DB06616 DB04377] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04377|Meglutol HMGCR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;HMGCR;CYP3A4 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HMGCR;HCK GO:0043066| negative regulation of apoptotic process SRC;HCK;HMGCR GO:0006629| lipid metabolic process HMGCR;CYP3A4 GO:0043407| negative regulation of MAP kinase activity LYN;HMGCR GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;ABL1;SRC;MAP2K2;MAP2K1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;HMGCR 5813:[DB06616 DB08206] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5814:[DB06616 DB02147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways GO:0050766| positive regulation of phagocytosis C3;BCR GO:0002376| immune system process LYN;C3;SRC;HCK GO:0007165| signal transduction MAP2K1;SRC;BCR;C3;LYN GO:0006954| inflammatory response HCK;LYN;C3 GO:0001934| positive regulation of protein phosphorylation LYN;C3;ABL1 GO:0006629| lipid metabolic process CYP3A4;C3 GO:0045087| innate immune response SRC;HCK;ABL1;C3;LYN 5815:[DB06616 DB04405] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04405|2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;CDK2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;MMP12 5816:[DB06616 DB04106] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04106|Fotemustine TXNRD1 common genes common pathways GO:0034599| cellular response to oxidative stress ABL1;TXNRD1 GO:0055114| oxidation-reduction process CYP3A4;TXNRD1;CYP2C8 GO:0007165| signal transduction LYN;SRC;BCR;TXNRD1;MAP2K1 GO:0008283| cell proliferation SRC;TXNRD1 5817:[DB06616 DB03042] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03042|5-Phosphoarabinonic Acid GPI common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPI 5818:[DB06616 DB00032] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00032|Menotropins FSHR;LHCGR common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;FSHR;SRC;LYN;LHCGR GO:0070374| positive regulation of ERK1 and ERK2 cascade FSHR;MAP2K2;SRC;MAP2K1;ABL1 GO:0001545| primary ovarian follicle growth SRC;FSHR;LHCGR 5819:[DB06616 DB03104] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03104|RU82129 SRC common genes SRC common pathways GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN GO:0071398| cellular response to fatty acid SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0060065| uterus development SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway SRC;BCR;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0086098| SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0038096| LYN;ABL1;SRC;HCK GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0038128| SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0042493| response to drug SRC;ABCB1;LYN GO:0038083| ABL1;SRC;HCK;LYN GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration SRC;LYN GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0060491| regulation of cell projection assembly SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0007417| central nervous system development SRC;LYN GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0071456| cellular response to hypoxia SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0046777| protein autophosphorylation ABL1;SRC;BCR;HCK;CAMK2G;LYN GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2 5820:[DB06616 DB01672] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01672|2,3-Dihydroxy-Benzoic Acid LCN2 common genes common pathways GO:0006915| apoptotic process ABL1;LCN2 GO:0002376| immune system process LYN;SRC;LCN2;HCK GO:0045087| innate immune response LYN;ABL1;SRC;LCN2;HCK 5821:[DB06616 DB00323] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways GO:0042493| response to drug LYN;COMT;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;COMT GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0014070| response to organic cyclic compound COMT;LYN GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 5822:[DB06616 DB11652] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11652|Tucatinib ERBB2 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;ERBB2 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ERBB2;ABL1;CAMK2G;LYN GO:0043406| positive regulation of MAP kinase activity SRC;ERBB2 GO:0008283| cell proliferation ERBB2;SRC GO:0045785| positive regulation of cell adhesion SRC;ERBB2 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;ERBB2 GO:0007165| signal transduction ERBB2;MAP2K1;SRC;BCR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway ERBB2;HCK;LYN GO:0043547| positive regulation of GTPase activity BCR;ERBB2 GO:0016310| phosphorylation ABL1;ERBB2;HCK;MAP2K1;SRC;MAP2K2;BCR;CDK2;LYN;CAMK2G;MAP3K2 GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ERBB2;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade SRC;ERBB2 GO:0000165| MAPKKK cascade CAMK2G;ERBB2;MAP2K1;MAP2K2 GO:0038128| ERBB2;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;ERBB2 GO:0001934| positive regulation of protein phosphorylation LYN;ERBB2;ABL1 GO:2000145| regulation of cell motility ERBB2;ABL1 GO:0007399| nervous system development CAMK2G;ERBB2 GO:0007507| heart development ERBB2;MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;ERBB2;LYN 5823:[DB06616 DB02141] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02141|S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;HCK;LYN GO:0043542| endothelial cell migration ABL1;NOS3 GO:0055114| oxidation-reduction process CYP3A4;NOS3;CYP2C8 GO:0008285| negative regulation of cell proliferation LYN;NOS3;MAP2K1 5824:[DB06616 DB08615] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0006260| DNA replication CDK2;ACHE 5825:[DB06616 DB13158] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13158|Clobetasone NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0051301| cell division CDK2;NR3C1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0007165| signal transduction NR3C1;LYN;MAP2K1;SRC;BCR GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0006915| apoptotic process NR3C1;ABL1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 5826:[DB06616 DB04112] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04112|1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide PLA2G2A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2A GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;PLA2G2A 5827:[DB06616 DB02097] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02097|Cytidine UCK2 common genes common pathways GO:0016310| phosphorylation MAP2K1;HCK;BCR;UCK2;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G 5828:[DB06616 DB14042] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14042|Galcanezumab CALCA;CALCB common genes common pathways GO:0043542| endothelial cell migration CALCA;ABL1 GO:0045087| innate immune response HCK;SRC;ABL1;CALCA;LYN GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CALCA;LYN;CDK2;CAMK2G GO:0007165| signal transduction CALCB;SRC;BCR;MAP2K1;LYN 5829:[DB06616 DB05416] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PPARD GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;PPARD GO:0043066| negative regulation of apoptotic process HCK;SRC;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;CDK2;PPARD GO:0007507| heart development MAP2K1;PPARD;PPARA GO:0006629| lipid metabolic process PPARA;CYP3A4;PPARD GO:0042127| regulation of cell proliferation PPARD;ABL1;SRC GO:0050728| negative regulation of inflammatory response PPARD;PPARA;BCR GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARD;PPARA GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CDK2;PPARD;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0030154| cell differentiation CAMK2G;PPARD;HCK GO:0071456| cellular response to hypoxia SRC;PPARD GO:0010628| positive regulation of gene expression PPARD;SRC;MAP2K1 GO:0010033| response to organic substance PPARD;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARD GO:0008283| cell proliferation SRC;PPARD GO:0032868| response to insulin stimulus PPARA;LYN GO:0006915| apoptotic process PPARD;ABL1 5830:[DB06616 DB05993] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05993|PRX-07034 HTR6 common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;HTR6 5831:[DB06616 DB13914] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13914|Volixibat SLC10A2 common genes common pathways GO:0006810| transport SLC10A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC10A2 5832:[DB06616 DB03317] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0034599| cellular response to oxidative stress ABL1;CYCS GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYCS;CYP2C9;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0006915| apoptotic process ABL1;CYCS GO:0006470| protein dephosphorylation CAMK2G;CYCS 5833:[DB06616 DB04027] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04027|D-Arginine CKM common genes common pathways GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G;CKM 5834:[DB06616 DB06433] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;TYMP GO:0051259| protein oligomerization CAMK2G;RRM1 GO:0006935| chemotaxis MAP2K1;TYMP GO:0000278| mitotic cell cycle ABL1;RRM1 GO:0055114| oxidation-reduction process RRM1;CYP2C8;CYP3A4 GO:0006260| DNA replication RRM1;CDK2 GO:0030154| cell differentiation CAMK2G;HCK;TYMP 5835:[DB06616 DB04516] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process ISYNA1;CYP3A4 5836:[DB06616 DB00548] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0031667| response to nutrient levels SRC;SRD5A2 GO:0042493| response to drug LYN;SRD5A2;ABCB1;SRC GO:0055114| oxidation-reduction process TYR;CYP2C8;SRD5A2;CYP3A4;AKR1D1 GO:0008209| androgen metabolic process AKR1D1;CYP3A4;SRD5A2 GO:0006629| lipid metabolic process CYP3A4;SRD5A2;AKR1D1 GO:0006706| steroid catabolic process SRD5A2;CYP3A4 GO:0014070| response to organic cyclic compound LYN;SRD5A2 GO:0008283| cell proliferation SRC;TYR GO:0010033| response to organic substance CDK2;SRD5A2 GO:0008202| steroid metabolic process AKR1D1;CYP3A4;SRD5A2;CYP2C8 GO:0043434| response to peptide hormone stimulus LYN;SRD5A2 GO:0030154| cell differentiation HCK;SRD5A2;CAMK2G GO:0048538| thymus development ABL1;TYR;MAP2K1 5837:[DB06616 DB03109] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03109|N-Acetyl-D-Allosamine CHIT1 common genes common pathways 5838:[DB06616 DB06727] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06727|Sparteine CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 5839:[DB06616 DB00406] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00406|Gentian violet cation SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 5840:[DB06616 DB09401] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:2000811| negative regulation of anoikis BCL2;SRC;MCL1;BCL2L1 GO:0001782| B cell homeostasis BCL2;LYN GO:0051924| regulation of calcium ion transport CAMK2G;BCL2 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway BCL2;BCL2L1;SRC;MCL1 GO:0010506| regulation of autophagy BCL2;ABL1 GO:0051902| negative regulation of mitochondrial depolarization SRC;BCL2 GO:0042493| response to drug BCL2;LYN;SRC;ABCB1 GO:0043066| negative regulation of apoptotic process BCL2L1;HCK;MCL1;SRC;BCL2 GO:0006897| endocytosis ABL1;BCL2L1 GO:0008284| positive regulation of cell proliferation HCK;BCL2L1;BCL2;LYN;CDK2 GO:0009615| response to virus SRC;BCL2L1 GO:0042542| response to hydrogen peroxide BCL2;SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1;BCL2 GO:0018105| peptidyl-serine phosphorylation BCL2;CDK2;CAMK2G;SRC GO:0043065| positive regulation of apoptotic process SRC;BCL2L1;ABL1 GO:0006974| response to DNA damage stimulus ABL1;BCL2;LYN;CDK2 GO:0042981| regulation of apoptotic process MAP2K1;MCL1;MAP2K2;BCL2L1;MAP3K2;BCL2 GO:0007275| multicellular organismal development MCL1;CAMK2G;CDK2 GO:0009791| post-embryonic development ABL1;BCL2 GO:0030336| negative regulation of cell migration BCL2;BCR GO:0050853| B cell receptor signaling pathway BCL2;LYN;ABL1 GO:0014911| positive regulation of smooth muscle cell migration BCL2;SRC GO:0008285| negative regulation of cell proliferation LYN;BCL2;MAP2K1 GO:0009636| response to toxin LYN;BCL2 GO:0006470| protein dephosphorylation CAMK2G;BCL2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis BCL2;MCL1;BCL2L1;ABL1 GO:0008283| cell proliferation BCL2;BCL2L1;SRC GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;BCR GO:0006915| apoptotic process BCL2;BCL2L1;ABL1;MCL1 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;BCL2;CAMK2G GO:0042100| B cell proliferation BCL2;ABL1 GO:0006979| response to oxidative stress BCL2;ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1;MCL1 GO:0048538| thymus development BCL2;ABL1;MAP2K1 GO:0048536| spleen development BCL2;ABL1 GO:0030097| hemopoiesis BCL2;LYN GO:0003014| renal system process BCR;BCL2 GO:0098609| BCL2;SRC GO:0045930| negative regulation of mitotic cell cycle ABL1;BCL2 GO:0071456| cellular response to hypoxia BCL2;SRC GO:0030154| cell differentiation HCK;MCL1;CAMK2G 5841:[DB06616 DB01818] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01818|O3-Sulfonylgalactose MBL2 common genes common pathways GO:0050766| positive regulation of phagocytosis MBL2;BCR GO:0002376| immune system process SRC;HCK;LYN;MBL2 GO:0006979| response to oxidative stress MBL2;ABL1 GO:0045087| innate immune response MBL2;LYN;ABL1;SRC;HCK 5842:[DB06616 DB05309] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05309|TP-508 FGF4 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;FGF4 GO:0010628| positive regulation of gene expression FGF4;MAP2K1;SRC GO:0030154| cell differentiation CAMK2G;HCK;FGF4 GO:0065009| regulation of molecular function FGF4;CAMK2G GO:0007165| signal transduction LYN;SRC;BCR;FGF4;MAP2K1 GO:0001934| positive regulation of protein phosphorylation ABL1;FGF4;LYN GO:0051897| positive regulation of protein kinase B signaling cascade FGF4;SRC GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;FGF4;MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;HCK;FGF4;MAP2K1;SRC;MAP2K2;BCR GO:0007275| multicellular organismal development CAMK2G;CDK2;FGF4 GO:0043066| negative regulation of apoptotic process SRC;FGF4;HCK GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;FGF4 5843:[DB06616 DB03621] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03621|L-709,587 FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway HCK;FKBP1A GO:0001933| negative regulation of protein phosphorylation LYN;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FKBP1A 5844:[DB06616 DB12212] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12212|Landiolol CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 5845:[DB06616 DB05050] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05050|ADL5859 OPRD1 common genes common pathways GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0007165| signal transduction LYN;OPRD1;MAP2K1;BCR;SRC GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;OPRD1 GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G 5846:[DB06616 DB00929] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways GO:0050728| negative regulation of inflammatory response PTGER4;BCR GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;PTGER4 GO:0032496| response to lipopolysaccharide BCR;PTGER2;PTGER4 GO:0042127| regulation of cell proliferation PTGER2;SRC;ABL1 GO:0009612| response to mechanical stimulus PTGER4;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGER4 GO:0050715| positive regulation of cytokine secretion SRC;PTGER4 GO:0007165| signal transduction MAP2K1;PTGER2;SRC;BCR;LYN;PTGER3;PTGER4 5847:[DB06616 DB01270] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01270|Ranibizumab VEGFA common genes common pathways GO:0010595| positive regulation of endothelial cell migration VEGFA;ABL1 GO:0030335| positive regulation of cell migration VEGFA;LYN GO:0071456| cellular response to hypoxia SRC;VEGFA GO:0030154| cell differentiation VEGFA;CAMK2G;HCK GO:0010628| positive regulation of gene expression VEGFA;SRC;MAP2K1 GO:0043406| positive regulation of MAP kinase activity VEGFA;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade VEGFA;MAP2K1;MAP2K2;SRC;ABL1 GO:0045785| positive regulation of cell adhesion VEGFA;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;VEGFA GO:0002576| platelet degranulation LYN;VEGFA GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;VEGFA GO:0042327| positive regulation of phosphorylation LYN;VEGFA GO:0043066| negative regulation of apoptotic process SRC;HCK;VEGFA GO:0051272| positive regulation of cellular component movement LYN;VEGFA GO:0007399| nervous system development VEGFA;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;CDK2 GO:0008360| regulation of cell shape VEGFA;HCK GO:0051894| positive regulation of focal adhesion assembly VEGFA;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;VEGFA GO:0007275| multicellular organismal development VEGFA;CAMK2G;CDK2 GO:0007498| mesoderm development VEGFA;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;VEGFA;LYN GO:0031954| positive regulation of protein autophosphorylation SRC;VEGFA GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;VEGFA GO:0001934| positive regulation of protein phosphorylation VEGFA;LYN;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;VEGFA 5848:[DB06616 DB01581] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01581|Sulfamerazine ALB common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation LYN;ALB 5849:[DB06616 DB07246] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;MMP9 GO:0001934| positive regulation of protein phosphorylation MMP9;LYN;ABL1 GO:0050900| leukocyte migration SRC;MMP9;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;MMP9 GO:0043065| positive regulation of apoptotic process SRC;ABL1;MMP9 GO:0048013| ephrin receptor signaling pathway MMP9;LYN;SRC GO:0034614| cellular response to reactive oxygen species MMP9;SRC GO:0030335| positive regulation of cell migration LYN;MMP9 5850:[DB06616 DB08810] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0007165| signal transduction LYN;HTR2A;HTR1A;HTR4;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0008283| cell proliferation SRC;HTR1A GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;HTR2A GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;CDK2;LYN;HCK GO:0016032| viral reproduction SRC;HCK;HTR2A;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0042493| response to drug HTR2A;LYN;ABCB1;SRC 5851:[DB06616 DB01000] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A2;SLC22A5;SLC15A1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 5852:[DB06616 DB06154] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4;ALDH2 GO:0042542| response to hydrogen peroxide HBA1;HBB;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;NOS3;HCK GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN;GUCY1A2 GO:0043542| endothelial cell migration ABL1;NOS3 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;NOS3 GO:0007596| blood coagulation LYN;HBB GO:0007165| signal transduction MAP2K1;SRC;BCR;GUCY1A2;LYN 5853:[DB06616 DB00847] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;CYP2C8;CYP3A4 GO:0042493| response to drug SST;LYN;SRC;ABCB1 GO:0009612| response to mechanical stimulus SRC;MPO GO:0043066| negative regulation of apoptotic process HCK;SRC;MPO GO:0032496| response to lipopolysaccharide BCR;MPO GO:0010447| response to acidity SST;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;SST GO:0043200| response to amino acid stimulus LYN;SST GO:0007165| signal transduction LYN;SRC;NPY2R;BCR;MAP2K1 GO:0065009| regulation of molecular function NPY2R;CAMK2G GO:0006979| response to oxidative stress ABL1;MPO GO:0007204| elevation of cytosolic calcium ion concentration NPY2R;ABL1 5854:[DB06616 DB07029] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;MAP2K1;MAP2K2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 5855:[DB06616 DB06939] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways GO:0043542| endothelial cell migration ABL1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK GO:0007155| cell adhesion HCK;SRC;ABL1;DPP4 GO:0031295| T cell costimulation LYN;DPP4;SRC 5856:[DB06616 DB06162] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06162|Lumiliximab FCER2 common genes common pathways 5857:[DB06616 DB04270] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction PPARG;LYN;BCR;SRC;MAP2K1 GO:0014070| response to organic cyclic compound PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0009612| response to mechanical stimulus PPARG;SRC GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug SRC;ABCB1;PPARG;LYN 5858:[DB06616 DB08186] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08186|(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE KAT2B common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;MAP3K2;KAT2B GO:0006355| regulation of transcription, DNA-dependent ABL1;KAT2B GO:0016032| viral reproduction KAT2B;LYN;HCK;SRC GO:0032869| cellular response to insulin stimulus SRC;KAT2B GO:0007050| cell cycle arrest KAT2B;ABL1;MAP2K1 GO:0007049| cell cycle SRC;KAT2B;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;KAT2B 5859:[DB06616 DB06097] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06097|GSK-923295 CENPE common genes common pathways GO:0007049| cell cycle CENPE;SRC;CDK2 GO:0007275| multicellular organismal development CENPE;CDK2;CAMK2G GO:0051301| cell division CDK2;CENPE GO:0000278| mitotic cell cycle ABL1;CENPE 5860:[DB06616 DB09459] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HIF1AN GO:0006355| regulation of transcription, DNA-dependent ABL1;HIF1AN 5861:[DB06616 DB08200] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08200|(1R)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0042493| response to drug SRC;ABCB1;BCHE;LYN GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 5862:[DB06616 DB05787] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05787|LM-609 ITGB3 common genes common pathways GO:0010595| positive regulation of endothelial cell migration ABL1;ITGB3 GO:0007229| integrin-mediated signaling pathway ABL1;ITGB3;HCK;SRC GO:0030168| platelet activation LYN;SRC;ITGB3 GO:0007596| blood coagulation LYN;ITGB3 GO:0002576| platelet degranulation LYN;ITGB3 GO:0048010| vascular endothelial growth factor receptor signaling pathway ITGB3;SRC GO:0007155| cell adhesion ABL1;ITGB3;HCK;SRC GO:0045124| regulation of bone resorption SRC;ITGB3 GO:0050900| leukocyte migration LYN;ITGB3;SRC GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;ITGB3 GO:0016032| viral reproduction LYN;SRC;HCK;ITGB3 GO:0034446| substrate adhesion-dependent cell spreading SRC;ITGB3;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ITGB3;SRC;ABL1 5863:[DB06616 DB08884] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ABCC4;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1;ABCC4;ABCC2 GO:0071222| cellular response to lipopolysaccharide ABL1;ABCC2;SRC;BCR GO:0002576| platelet degranulation LYN;ABCC4 GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:0010033| response to organic substance CDK2;ABCC4 GO:0055085| transmembrane transport ABCC3;SLCO1B3;SLCO1B1;ABCB1;ABCC4;ABCC2 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC3 GO:0014070| response to organic cyclic compound LYN;ABCC4 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0006810| transport ABCC3;ABCC2;ABCB1 GO:0042908| xenobiotic transport ABCC3;ABCB1 5864:[DB06616 DB12712] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12712|Pilsicainide ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB11;ABCB1 GO:0006810| transport ABCB11;ABCB1 5865:[DB06616 DB12961] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARA GO:0050728| negative regulation of inflammatory response PPARA;BCR GO:0006954| inflammatory response LTB4R;LYN;HCK GO:0006935| chemotaxis MAP2K1;LTB4R2 GO:0006629| lipid metabolic process PPARA;CYP3A4 GO:0007507| heart development MAP2K1;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;CDK2 GO:0032868| response to insulin stimulus LYN;PPARA GO:0006928| cellular component movement LTB4R;MAP2K1 GO:0007165| signal transduction BCR;LTB4R2;SRC;MAP2K1;LYN;LTB4R 5866:[DB06616 DB05458] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways GO:0006281| DNA repair ABL1;CHRNA4;CDK2 GO:0006816| calcium ion transport CHRNB2;CAMK2G;CHRNA4 GO:0006979| response to oxidative stress ABL1;CHRNA4 GO:0007165| signal transduction CHRNB2;LYN;MAP2K1;SRC;CHRNA4;BCR 5867:[DB06616 DB05190] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05190|XL281 BRAF;RAF1 common genes common pathways GO:1900026| ABL1;BRAF GO:0030878| thyroid gland development BRAF;MAP2K1;RAF1 GO:0048538| thymus development BRAF;MAP2K1;ABL1;RAF1 GO:0007165| signal transduction MAP2K1;BCR;BRAF;SRC;RAF1;LYN GO:0043434| response to peptide hormone stimulus BRAF;LYN GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;BRAF;SRC;ABL1;RAF1;MAP3K2;LYN;CDK2;CAMK2G GO:0000186| activation of MAPKK activity BRAF;RAF1;MAP3K2 GO:0030168| platelet activation LYN;RAF1;SRC GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;BRAF;SRC;ABL1;RAF1;MAP3K2;CDK2;LYN;CAMK2G GO:0030154| cell differentiation CAMK2G;RAF1;BRAF;HCK GO:0010628| positive regulation of gene expression BRAF;SRC;MAP2K1 GO:0046632| alpha-beta T cell differentiation ABL1;BRAF GO:0008285| negative regulation of cell proliferation RAF1;LYN;MAP2K1 GO:0051496| positive regulation of stress fiber assembly BRAF;ABL1 GO:0008283| cell proliferation SRC;RAF1 GO:2000352| negative regulation of endothelial cell apoptosis BRAF;ABL1 GO:0006915| apoptotic process RAF1;ABL1 GO:0045580| regulation of T cell differentiation BRAF;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;BRAF;RAF1 GO:0035556| intracellular signal transduction CAMK2G;LYN;RAF1;SRC;BCR;BRAF GO:2000145| regulation of cell motility ABL1;RAF1 GO:0043066| negative regulation of apoptotic process RAF1;BRAF;SRC;HCK GO:0050772| positive regulation of axonogenesis MAP2K1;BRAF GO:0007507| heart development MAP2K1;RAF1 GO:0042981| regulation of apoptotic process MAP3K2;RAF1;MAP2K1;MAP2K2 GO:0042127| regulation of cell proliferation ABL1;SRC;BRAF GO:0048679| regulation of axon regeneration BRAF;MAP2K1 GO:0007275| multicellular organismal development RAF1;CAMK2G;CDK2 GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;RAF1;SRC GO:0060324| face development BRAF;MAP2K1;RAF1 GO:0000165| MAPKKK cascade RAF1;CAMK2G;MAP2K1;BRAF;MAP2K2 GO:0035023| regulation of Rho protein signal transduction RAF1;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process RAF1;SRC GO:0048011| nerve growth factor receptor signaling pathway SRC;RAF1 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;RAF1 5868:[DB06616 DB08609] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08609|(2R)-N-{4-[Ethyl(phenyl)sulfamoyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide PDK2 common genes common pathways GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;PDK2;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0016310| phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;PDK2;MAP3K2 GO:0034614| cellular response to reactive oxygen species PDK2;SRC 5869:[DB06616 DB01437] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007420| brain development BCR;GABRA5 GO:0007165| signal transduction GABRA6;GABRD;LYN;GABRP;GABRE;GABRB1;GABRA5;GABRQ;GABRB3;BCR;SRC;MAP2K1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP11A1;CYP3A4;CYP2C8;CYP2D6 GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0006810| transport GABRA1;GABRD;GABRB2;GABRA6;GABRA4;GABRA3;GABRG2;GABRB1;GABRA5;GABRB3;ABCB1 GO:0042359| vitamin D metabolic process CYP11A1;CYP3A4 GO:0009791| post-embryonic development GABRG2;ABL1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0009636| response to toxin GABRB1;LYN GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP11A1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1;GABRG3 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4;CYP11A1 5870:[DB06616 DB06778] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes common pathways GO:0055114| oxidation-reduction process LOX;MAOB;MT-CO1;MAOA;PAH;CYP3A4;SOD1;CP;TYR;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LOX;MAOB;SOD1;LYN GO:0031667| response to nutrient levels SRC;SOD1 GO:0051602| response to electrical stimulus SRC;MT-CO1 GO:0034599| cellular response to oxidative stress ABL1;SOD1 GO:0048678| response to axon injury SOD1;LYN GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0007507| heart development MAP2K1;LOX GO:0042542| response to hydrogen peroxide SOD1;SRC GO:0043065| positive regulation of apoptotic process SOD1;ABL1;SRC GO:0002576| platelet degranulation ALB;LYN;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;ALB;HCK;SRC GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;SOD1;MAP3K2 GO:0008283| cell proliferation TYR;SRC GO:0009636| response to toxin LYN;MAOB GO:0006464| protein modification process ABL1;LOX GO:0010033| response to organic substance SOD1;CDK2 GO:0009725| response to hormone stimulus LYN;LOX GO:0048538| thymus development ABL1;TYR;MAP2K1;SOD1 GO:0006979| response to oxidative stress MT-CO1;SOD1;ABL1 5871:[DB06616 DB01038] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;DRD2;DRD1 GO:0035556| intracellular signal transduction DRD2;SRC;BCR;LYN;CAMK2G GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0048678| response to axon injury LYN;DRD2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;DRD1 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0009636| response to toxin DRD2;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;DRD2;SRC;MAP2K1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0030900| forebrain development SRC;DRD2 GO:1903351| ABL1;DRD1 GO:0007165| signal transduction DRD1;MAP2K1;DRD5;BCR;SRC;DRD2;LYN GO:0030335| positive regulation of cell migration DRD1;LYN 5872:[DB06616 DB06204] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0007420| brain development BCR;SLC6A4 GO:0007165| signal transduction MAP2K1;HTR3A;BCR;SRC;OPRK1;OPRD1;OPRM1;LYN GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP3A4;UGT1A9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0006810| transport SLC6A2;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT2B7;CYP2C8;CYP2C19;CYP2D6 GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN GO:0010033| response to organic substance CDK2;SLC6A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010628| positive regulation of gene expression SLC6A4;MAP2K1;SRC GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;OPRM1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0009636| response to toxin SLC6A4;LYN GO:0006629| lipid metabolic process CYP2C9;CYP3A4;CYP2D6;UGT2B7 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;UGT1A9;CYP2C9;CYP3A4 GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;BCR;SRC GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0042737| drug catabolic process CYP2C9;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0042493| response to drug ABCB1;SRC;SLC6A4;SLC6A2;LYN GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C19;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;OPRD1 5873:[DB06616 DB09028] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;CHRNA7 GO:0006281| DNA repair CHRNA4;ABL1;CDK2 GO:0007399| nervous system development CAMK2G;CHRNA3 GO:0006816| calcium ion transport CHRNA7;CHRNA4;CAMK2G;CHRNB2 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;LYN GO:0006979| response to oxidative stress ABL1;CHRNA4 GO:0007165| signal transduction CHRNA6;LYN;CHRNB2;CHRNA7;CHRNA3;CHRNA4;SRC;BCR;MAP2K1 GO:0006810| transport ABCB1;CHRNA6 GO:0000187| activation of MAPK activity CHRNA7;MAP2K2;MAP2K1;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;CHRNA7 5874:[DB06616 DB08234] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 5875:[DB06616 DB05777] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways GO:0007275| multicellular organismal development F2;CDK2;CAMK2G GO:0008360| regulation of cell shape HCK;F2 GO:0008284| positive regulation of cell proliferation F2;HCK;LYN;CDK2 GO:0002576| platelet degranulation LYN;F5 GO:0001934| positive regulation of protein phosphorylation ABL1;F2;LYN GO:0050900| leukocyte migration F2;SRC;LYN GO:0030168| platelet activation LYN;F2;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol F2;ABL1 GO:1900182| SRC;F2 GO:0007596| blood coagulation LYN;F5;F2 5876:[DB06616 DB00452] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00452|Framycetin rpsL;CXCR4 common genes common pathways GO:0006935| chemotaxis MAP2K1;CXCR4 GO:0009615| response to virus SRC;CXCR4 GO:0006954| inflammatory response HCK;CXCR4;LYN GO:0016032| viral reproduction CXCR4;HCK;SRC;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CXCR4 GO:0007165| signal transduction LYN;CXCR4;MAP2K1;BCR;SRC GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2;CXCR4 GO:0006915| apoptotic process CXCR4;ABL1 GO:0007411| axon guidance CXCR4;SRC 5877:[DB06616 DB04638] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04638|2,5-DI-(TERT-BUTYL)-1,4,BENZOHYDROQUINONE ATP2A1 common genes common pathways GO:0006816| calcium ion transport ATP2A1;CAMK2G 5878:[DB06616 DB03351] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03351|Sri-9439 DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 5879:[DB06616 DB00937] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug ABCB1;SRC;SLC6A3;SLC6A2;LYN GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1 GO:0006810| transport ABCB1;SLC6A2 5880:[DB06616 DB01199] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01199|Tubocurarine CHRNA2;HTR3A;ACHE;CHRNA7;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0008283| cell proliferation SRC;ACHE GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;ABL1;MAP2K1;SRC;MAP2K2 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0000187| activation of MAPK activity MAP3K2;CHRNA7;MAP2K1;MAP2K2 GO:0007165| signal transduction CHRNA7;CHRNA2;HTR3A;MAP2K1;SRC;BCR;LYN GO:0006816| calcium ion transport CHRNA7;CAMK2G GO:0006260| DNA replication ACHE;CDK2 GO:0042493| response to drug BCHE;LYN;SRC;ABCB1 GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRNA7;HCK GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK 5881:[DB06616 DB13191] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A8 GO:0006810| transport SLC6A8;ABCB1 GO:0016310| phosphorylation CKM;CAMK2G;CKMT1A;LYN;CDK2;MAP3K2;CKMT2;ABL1;CKB;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0007420| brain development BCR;CKB 5882:[DB06616 DB09067] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;CRHR1;LYN 5883:[DB06616 DB08605] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways GO:0006629| lipid metabolic process DECR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;DECR1;CYP2C8 5884:[DB06616 DB05934] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05934|CTCE-0214 CXCL12 common genes common pathways GO:0007155| cell adhesion ABL1;SRC;HCK;CXCL12 GO:0009615| response to virus CXCL12;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;CXCL12;HCK GO:0006935| chemotaxis CXCL12;MAP2K1 GO:0009612| response to mechanical stimulus CXCL12;SRC GO:0051924| regulation of calcium ion transport CXCL12;CAMK2G GO:0007420| brain development CXCL12;BCR GO:0007165| signal transduction CXCL12;LYN;MAP2K1;BCR;SRC GO:0030335| positive regulation of cell migration LYN;CXCL12 GO:0043434| response to peptide hormone stimulus CXCL12;LYN GO:0007411| axon guidance CXCL12;SRC GO:0045785| positive regulation of cell adhesion SRC;CXCL12 5885:[DB06616 DB06186] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06186|Ipilimumab CTLA4 common genes common pathways GO:0043065| positive regulation of apoptotic process ABL1;SRC;CTLA4 GO:0006974| response to DNA damage stimulus LYN;CDK2;CTLA4;ABL1 GO:0050777| negative regulation of immune response LYN;CTLA4 GO:0002250| adaptive immune response CTLA4;LYN GO:0002376| immune system process SRC;HCK;CTLA4;LYN GO:0031295| T cell costimulation LYN;SRC;CTLA4 GO:0030889| negative regulation of B cell proliferation LYN;CTLA4 GO:0050853| B cell receptor signaling pathway LYN;CTLA4;ABL1 5886:[DB06616 DB06408] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;ENPP1 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;NT5C2;LYN;CAMK2G;MAP3K2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;NT5C2 GO:0055114| oxidation-reduction process CYP3A4;IMPDH1;CYP2C8 5887:[DB06616 DB03126] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03126|Mant-Adp MYH14 common genes common pathways GO:0008360| regulation of cell shape HCK;MYH14 5888:[DB06616 DB04977] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1;CYP2A6;CYP4A11 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042493| response to drug CYP2E1;LYN;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP4A11;CYP2E1;CYP3A4;CYP2A6 GO:0008209| androgen metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0097267| CYP4A11;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2A6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2A6;CYP3A4;CYP2E1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 5889:[DB06616 DB05931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05931|Pegdinetanib KDR common genes common pathways GO:0007275| multicellular organismal development KDR;CDK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;BCR;MAP2K2;SRC;KDR;MAP2K1;HCK GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0008360| regulation of cell shape KDR;HCK GO:0043066| negative regulation of apoptotic process SRC;KDR;HCK GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR GO:0008284| positive regulation of cell proliferation CDK2;LYN;KDR;HCK GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0010629| negative regulation of gene expression MAP2K1;KDR;MAP2K2 GO:0038083| LYN;ABL1;SRC;KDR;HCK GO:0016032| viral reproduction SRC;KDR;HCK;LYN GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0030154| cell differentiation CAMK2G;KDR;HCK GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;MAP2K2;BCR;HCK;MAP2K1;KDR;ABL1 GO:0030335| positive regulation of cell migration LYN;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;KDR GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade KDR;MAP2K1;SRC;MAP2K2;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0046777| protein autophosphorylation BCR;SRC;KDR;HCK;ABL1;CAMK2G;LYN 5890:[DB06616 DB01520] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways GO:0048013| ephrin receptor signaling pathway GRIN2B;LYN;SRC GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;CHRNA7 GO:0065009| regulation of molecular function GRIN2B;CAMK2G;GRIN2D;GRIN2C;GRIN2A GO:0007165| signal transduction CHRNA7;SRC;BCR;MAP2K1;LYN GO:0006810| transport ABCB1;GRIN2A;GRIN2C;GRIN2B GO:0000165| MAPKKK cascade GRIN2D;GRIN2C;GRIN2B;CAMK2G;MAP2K1;MAP2K2;GRIN2A GO:0051924| regulation of calcium ion transport CAMK2G;GRIN3B GO:0006816| calcium ion transport CAMK2G;GRIN3A;CHRNA7;GRIN2A GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7;ABL1 GO:0050885| neuromuscular process controlling balance GRIN2C;BCR;ABL1 GO:1901216| GRIN2B;ABL1 GO:0042493| response to drug SRC;ABCB1;GRIN2A;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;CHRNA7 GO:0043065| positive regulation of apoptotic process SRC;GRIN2A;ABL1 5891:[DB06616 DB00724] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0002376| immune system process TLR7;LYN;TLR8;HCK;SRC GO:0007165| signal transduction TLR8;BCR;SRC;MAP2K1;LYN;TLR7 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0001932| regulation of protein phosphorylation TLR8;MAP2K1;TLR7;LYN GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0009615| response to virus TLR8;SRC GO:0071260| cellular response to mechanical stimulus TLR7;MAP3K2;TLR8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0045087| innate immune response LYN;TLR7;ABL1;TLR8;SRC;HCK GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0050707| regulation of cytokine secretion LYN;TLR8 GO:0006954| inflammatory response TLR7;LYN;TLR8;HCK 5892:[DB06616 DB03467] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes ABCB1 common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1;CDK2 GO:0007155| cell adhesion ABL1;HCK;CYP1B1;SRC GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1B1;CYP3A4;AKR1C1 GO:0060065| uterus development ESR1;CYP19A1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0043065| positive regulation of apoptotic process SRC;CYP1B1;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC;ESR1 GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;AKR1C1;CYP2C8;CYP1B1 GO:2001225| regulation of chloride transport ABCB1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;ESR2;MAP3K2;ESR1;CDK2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0042493| response to drug LYN;ABCC1;ABCG2;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1;ESR1 GO:0097267| CYP1B1;CYP2C8 GO:0007165| signal transduction ESR1;LYN;SRC;BCR;MAP2K1;ESR2 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0006810| transport ABCC1;ABCB1;ABCG2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP1B1;CYP2C8;CYP3A4 GO:0072089| stem cell proliferation ABCB1 GO:0008285| negative regulation of cell proliferation MAP2K1;CYP1B1;LYN GO:0070301| cellular response to hydrogen peroxide CYP1B1;ABL1 GO:0030336| negative regulation of cell migration CYP1B1;BCR GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLCO2B1;ABCG2;ABCB1 GO:0009636| response to toxin LYN;CYP1B1 5893:[DB06616 DB02230] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02230|Immucillin-G PNP common genes common pathways GO:0042493| response to drug PNP;LYN;ABCB1;SRC 5894:[DB06616 DB00364] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways GO:0010628| positive regulation of gene expression EGF;MAP2K1;SRC GO:0043406| positive regulation of MAP kinase activity FGF2;EGF;SRC GO:2000352| negative regulation of endothelial cell apoptosis FGG;FGA;FGB;ABL1 GO:0007596| blood coagulation FGB;FGA;FGG;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;FGA;MAP2K2;FGB;SRC;ABL1;FGG;FGF2 GO:0000187| activation of MAPK activity EGF;FGF2;MAP3K2;MAP2K2;MAP2K1 GO:0002376| immune system process FGB;SRC;HCK;FGA;LYN GO:1900026| FGA;FGB;ABL1;FGG GO:0007165| signal transduction EGF;LYN;FGF2;FGG;SRC;FGB;BCR;FGA;MAP2K1 GO:0072089| stem cell proliferation ABCB1;FGF2 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;FGF2;SRC GO:0030335| positive regulation of cell migration EGF;LYN GO:0030154| cell differentiation FGF2;CAMK2G;HCK GO:0000186| activation of MAPKK activity MAP3K2;EGF GO:0030168| platelet activation FGA;FGB;SRC;LYN;FGG GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;EGF GO:0038128| EGF;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;EGF GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;EGF;FGF2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;FGF2;EGF GO:0006260| DNA replication EGF;CDK2 GO:0002250| adaptive immune response LYN;FGA;FGB GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;FGF2;CDK2;EGF GO:0007173| epidermal growth factor receptor signaling pathway EGF;ABL1;SRC GO:0002576| platelet degranulation EGF;LYN;FGG;ALB;FGB;FGA GO:0006935| chemotaxis FGF2;MAP2K1 GO:0008284| positive regulation of cell proliferation EGF;LYN;CDK2;FGF2;HCK GO:2000145| regulation of cell motility ABL1;EGF GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0042327| positive regulation of phosphorylation EGF;LYN GO:0045087| innate immune response HCK;FGA;FGB;SRC;ABL1;LYN GO:0007399| nervous system development FGF2;CAMK2G GO:0007265| Ras protein signal transduction CDK2;FGF2 GO:0007275| multicellular organismal development FGF2;CAMK2G;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;EGF;FGF2 5895:[DB06616 DB02911] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02911|2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;NOS3;MAP2K1 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;HCK;LYN GO:0043542| endothelial cell migration NOS3;ABL1 GO:0055114| oxidation-reduction process CYP3A4;NOS3;CYP2C8 5896:[DB06616 DB07579] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07579|BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE APCS common genes common pathways GO:0045087| innate immune response ABL1;SRC;HCK;LYN;APCS 5897:[DB06616 DB07756] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways GO:0006260| DNA replication CDK2;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0008283| cell proliferation ACHE;SRC 5898:[DB06616 DB08612] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 5899:[DB06616 DB08347] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08347|4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile ADRB1 common genes common pathways GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0007165| signal transduction LYN;BCR;SRC;ADRB1;MAP2K1 5900:[DB06616 DB07142] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 5901:[DB06616 DB08360] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08360|2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0016236| macroautophagy SRC;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:1901796| CDK2;CSNK2A1 GO:0008284| positive regulation of cell proliferation CSNK2A1;CDK2;LYN;HCK GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CSNK2A1;CAMK2G GO:0007049| cell cycle CSNK2A1;CDK2;SRC GO:0016310| phosphorylation CDK2;LYN;CAMK2G;CSNK2A1;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;CSNK2A1;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;CSNK2A1 5902:[DB06616 DB02888] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02888|FKB-001 FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;ABL1 GO:0001933| negative regulation of protein phosphorylation FKBP1A;LYN GO:0019221| cytokine-mediated signaling pathway HCK;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;SRC 5903:[DB06616 DB03766] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;GPHN;CYP3A4 GO:0050727| regulation of inflammatory response FABP4;HCK;LYN GO:0045892| negative regulation of transcription, DNA-dependent FABP4;SRC 5904:[DB06616 DB01193] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0045453| bone resorption SRC;ADRB2 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction LYN;ADRB2;BCR;SRC;ADRB1;MAP2K1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0045332| phospholipid translocation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug LYN;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 5905:[DB06616 DB03552] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03552|3-Tyrosine TH common genes common pathways GO:0043434| response to peptide hormone stimulus TH;LYN GO:0014070| response to organic cyclic compound TH;LYN GO:0007507| heart development MAP2K1;TH GO:0032496| response to lipopolysaccharide BCR;TH GO:0051602| response to electrical stimulus TH;SRC GO:0031667| response to nutrient levels TH;SRC GO:0042493| response to drug LYN;TH;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;TH 5906:[DB06616 DB02464] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways GO:0045785| positive regulation of cell adhesion PRSS2;SRC 5907:[DB06616 DB03585] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03585|Oxyphenbutazone PLA2G2E;ALB;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0006954| inflammatory response PLA2G2E;HCK;LYN GO:0055085| transmembrane transport SLC22A6;ABCB1 5908:[DB06616 DB08208] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes MAP2K1 common pathways GO:0050772| positive regulation of axonogenesis MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1 GO:0007507| heart development MAP2K1 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;MAP2K1 GO:0021697| cerebellar cortex formation MAP2K1 GO:0006935| chemotaxis MAP2K1 GO:0060674| placenta blood vessel development MAP2K1 GO:0048679| regulation of axon regeneration MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;LYN GO:0048870| cell motility MAP2K1 GO:0001932| regulation of protein phosphorylation LYN;MAP2K1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1 GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0090398| cellular senescence MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2 GO:0060324| face development MAP2K1 GO:0060425| lung morphogenesis MAP2K1 GO:0060440| trachea formation MAP2K1 GO:0035897| proteolysis in other organism MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2 GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K1;MAP2K2 GO:0007050| cell cycle arrest MAP2K1;ABL1 GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1 GO:0030878| thyroid gland development MAP2K1 GO:0048538| thymus development MAP2K1;ABL1 GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:1903800| MAP2K2;MAP2K1 GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1 GO:0090170| regulation of Golgi inheritance MAP2K2;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0006928| cellular component movement MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0060711| labyrinthine layer development MAP2K1 GO:0030216| keratinocyte differentiation MAP2K1 GO:0030182| neuron differentiation ABL1;MAP2K1 5909:[DB06616 DB02468] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;HMOX1 GO:0006979| response to oxidative stress ABL1;HMOX1 GO:0071456| cellular response to hypoxia SRC;HMOX1 GO:0034605| cellular response to heat HMOX1;LYN GO:0008285| negative regulation of cell proliferation HMOX1;LYN;MAP2K1 GO:0006915| apoptotic process ABL1;HMOX1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;HMOX1 GO:0035556| intracellular signal transduction SRC;BCR;HMOX1;CAMK2G;LYN GO:0043065| positive regulation of apoptotic process HMOX1;ABL1;SRC GO:0042542| response to hydrogen peroxide SRC;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;HMOX1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HMOX1 5910:[DB06616 DB08000] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08000|2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 5911:[DB06616 DB00171] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes ABCB1;ABL1 common pathways GO:0050885| neuromuscular process controlling balance BCR;ABL1 GO:0023014| signal transduction via phosphorylation event ACVRL1;ACVR1B;LYN;ACVR1;AMHR2 GO:0050900| leukocyte migration SRC;PIK3CA;LYN GO:0000278| mitotic cell cycle PPP5C;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process AKT1;CSNK2A1;SRC GO:0099040| ABCB1 GO:0001934| positive regulation of protein phosphorylation AKT1;LYN;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0055114| oxidation-reduction process CYP2C8;ABCC4;CYP3A4 GO:0006914| autophagy PRKAA1;ABL1 GO:2001225| regulation of chloride transport ABCB1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;AKT1;ACVR1B;ACVRL1 GO:0038083| HCK;SRC;ABL1;TNK2;ABL2;LYN GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0042493| response to drug ADCY1;ABCC4;ABCB1;SRC;ACSL1;ABCC2;ABCC6;ABCA1;ABCC1;ABCC8;LYN;ABCC9 GO:0016236| macroautophagy CSNK2A1;SRC;PRKAA1;CSNK2B GO:0006355| regulation of transcription, DNA-dependent ABL1;PRKAA1;ACVRL1;ACVR1B;ABCG1;CSNK2A1 GO:1900042| ABL1 GO:1901216| ABL1 GO:1904531| ABL1 GO:0006909| phagocytosis PIK3CA;HCK;ABL1 GO:0010506| regulation of autophagy ABL1;ABL2 GO:0045893| positive regulation of transcription, DNA-dependent AKT1;MAP3K2;ACVR1;CDK2;ACVRL1;MAP2K1;MAP2K2;SRC GO:0007173| epidermal growth factor receptor signaling pathway AKT1;SRC;PIK3CA;ABL1 GO:0031667| response to nutrient levels ASNS;SRC GO:1902036| ABL1 GO:0038096| SRC;PIK3CA;HCK;ABL1;LYN GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0030036| actin cytoskeleton organization BCR;ABL1 GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0038128| PIK3CA;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;TNK2 GO:0000165| MAPKKK cascade ARAF;MAP2K2;MAP2K1;CAMK2G;PPP5C GO:0000082| G1/S transition of mitotic cell cycle ACVR1;CDK2;ACVR1B;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CA;SRC GO:0002250| adaptive immune response LYN;PIK3CA GO:0010976| positive regulation of neuron projection development LYN;ABL2 GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1 GO:0006298| mismatch repair ABL1 GO:0006954| inflammatory response AKT1;LYN;HCK;PIK3CA GO:0042770| signal transduction in response to DNA damage ABL1 GO:0016032| viral reproduction SLC25A4;LYN;HCK;SRC GO:2000811| negative regulation of anoikis PIK3CA;SRC GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;PPP5C GO:0007275| multicellular organismal development CAMK2G;CDK2;AKT1;APAF1;ARAF GO:0007498| mesoderm development ACVR1;HCK GO:0043542| endothelial cell migration ABL1;PIK3CA GO:0018108| peptidyl-tyrosine phosphorylation ABL2;LYN;ALK;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0051259| protein oligomerization PPP5C;CAMK2G GO:0030516| regulation of axon extension ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1;TNK2;ALK;ABL2 GO:1905244| ABL1 GO:1901529| ABCB1 GO:0045931| positive regulation of mitotic cell cycle ASNS;ABL1 GO:0032496| response to lipopolysaccharide ABCC2;BCR;ABCC8 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1;ABL2 GO:0001933| negative regulation of protein phosphorylation PPP5C;LYN GO:0038189| ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0007155| cell adhesion ABL2;ABL1;SRC;HCK GO:0045087| innate immune response ABL1;SRC;PIK3CA;HCK;LYN;ABL2;TNK2 GO:0048668| collateral sprouting ABL1 GO:0007507| heart development ACVR1;MAP2K1 GO:0032148| activation of protein kinase B activity SRC;AKT1 GO:2000772| regulation of cellular senescence ABL1 GO:0007399| nervous system development CAMK2G;AKT1;ALK;APAF1 GO:0042981| regulation of apoptotic process APAF1;MAP2K1;MAP2K2;NAE1;MAP3K2;ALK;AKT1 GO:0006629| lipid metabolic process ABCA1;CYP3A4;PRKAA1;ACSL1 GO:0006281| DNA repair ABL1;PPP5C;CDK2 GO:0006974| response to DNA damage stimulus AKT1;PPP5C;LYN;CDK2;ABL1 GO:0051882| mitochondrial depolarization ABL1 GO:0071260| cellular response to mechanical stimulus AKT1;MAP3K2 GO:1901796| AKT1;CSNK2A1;CDK2;PRKAA1;CSNK2B GO:0002576| platelet degranulation LYN;ABCC4 GO:0043065| positive regulation of apoptotic process ABL1;APAF1;SRC;AKT1 GO:0042542| response to hydrogen peroxide SRC;PRKAA1 GO:0051726| regulation of cell cycle CDK15;BCR;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation AKT1;CAMK2G;CDK2;SRC GO:0071222| cellular response to lipopolysaccharide ABCA1;SRC;BCR;ABCC2;ABL1 GO:0008284| positive regulation of cell proliferation HCK;PRKAA1;AKT1;CSNK2A1;CDK2;LYN GO:1904528| ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL2;ABL1 GO:0071300| cellular response to retinoic acid LYN;ABL2;ABCA1 GO:2000145| regulation of cell motility ABL2;ABL1 GO:0035556| intracellular signal transduction AKT1;LYN;CAMK2G;ADCY1;SRC;BCR;ARAF GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:0006897| endocytosis ABL1;TNK2 GO:1900275| ABL1 GO:0030155| regulation of cell adhesion ABL2;ABL1 GO:0048010| vascular endothelial growth factor receptor signaling pathway PIK3CA;SRC GO:0009612| response to mechanical stimulus ASNS;SRC GO:0071560| cellular response to transforming growth factor beta stimulus APAF1;SRC;ACVRL1 GO:0030035| microspike assembly ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;PRKAA1;ARAF;AKT1;ASNS GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;AKT1;HCK GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1 GO:0032868| response to insulin stimulus LYN;ABCC8 GO:0042100| B cell proliferation ABL1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0045184| establishment of protein localization ABL1 GO:0018107| peptidyl-threonine phosphorylation CSNK2B;MAP2K1;CSNK2A1;AKT1;ACVR1;ACVR1B;CAMK2G GO:0055085| transmembrane transport ABCG1;ABCC1;ABCA1;ABCC6;SLC25A4;CFTR;ABCB11;ABCC9;ABCC8;ABCC4;ABCB1;ABCC2 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;ARAF GO:0006915| apoptotic process APAF1;ABL1;NAE1;AKT1;CSNK2A1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0000187| activation of MAPK activity MAP3K2;ALK;MAP2K2;PRKAA1;MAP2K1 GO:0045580| regulation of T cell differentiation ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway ACVRL1;AMHR2;ACVR1;SRC GO:0002322| B cell proliferation involved in immune response ABL1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;ACVR1 GO:0030182| neuron differentiation ABL1;MAP2K1 GO:0038095| LYN;PIK3CA GO:0008283| cell proliferation SRC;AKT1;ALK GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1 GO:0043200| response to amino acid stimulus LYN;ASNS GO:0016477| cell migration SRC;TNK2 GO:0006470| protein dephosphorylation PPP5C;CAMK2G GO:0014070| response to organic cyclic compound ABCC4;ACSL1;LYN GO:0009636| response to toxin LYN;ASNS GO:0007411| axon guidance SRC;PIK3CA GO:0070301| cellular response to hydrogen peroxide ABL1;PRKAA1;PPP5C GO:0008285| negative regulation of cell proliferation ACVRL1;LYN;MAP2K1;CSNK2B GO:0046632| alpha-beta T cell differentiation ABL1 GO:0010033| response to organic substance CDK2;AKT1;ABCG1;ACSL1;ABCC4 GO:0007049| cell cycle CDK2;NAE1;CSNK2A1;SRC GO:0006464| protein modification process ABL1;ARAF;ABL2;AKT1 GO:0001922| B-1 B cell homeostasis ABL1 GO:0050853| B cell receptor signaling pathway ABL1;LYN GO:0030336| negative regulation of cell migration ACVRL1;BCR GO:1900272| ABL1 GO:1990051| ABL1 GO:0009791| post-embryonic development ABL1 GO:0051895| negative regulation of focal adhesion assembly ACVRL1;SRC GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN;ACVR1B;ALK;AKT1 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1;ACSL1 GO:0010628| positive regulation of gene expression PRKAA1;SRC;MAP2K1;ACVR1B GO:0002333| transitional one stage B cell differentiation ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0034614| cellular response to reactive oxygen species AKT1;SRC GO:0006468| protein phosphorylation CAMK2G;ACVRL1;LYN;CDK2;CDK15;ACVR1B;ABL2;TNK2;ACVR1;AKT1;ALK;CSNK2A1;MAP3K2;AMHR2;ABL1;ARAF;BCR;PRKAA1;MAP2K2;SRC;PIK3CA;MAP2K1;HCK GO:0030154| cell differentiation APAF1;ARAF;HCK;CAMK2G;TNK2;AKT1 GO:0071456| cellular response to hypoxia AKT1;SRC;PRKAA1 GO:0007204| elevation of cytosolic calcium ion concentration ABL2;ABL1 GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0032869| cellular response to insulin stimulus SRC;AKT1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0006810| transport ABCB1;ASNA1;ABCC2;SLC25A4;ABCC6;ABCC1;ABCB11 GO:0000186| activation of MAPKK activity ARAF;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0001843| neural tube closure APAF1;ABL1 GO:0030168| platelet activation LYN;AKT1;PIK3CA;SRC GO:1903053| ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:0007417| central nervous system development ACVR1B;LYN;SRC GO:0016310| phosphorylation PIK3CA;SRC;BCR;MAP2K2;PRKAA1;HCK;MAP2K1;ABL1;ADK;ARAF;ACVR1;TNK2;MAP3K2;CSNK2A1;AMHR2;ALK;AKT1;ACVRL1;CAMK2G;ACVR1B;ABL2;CDK15;NT5C2;CDK2;LYN GO:0031295| T cell costimulation LYN;AKT1;SRC;PIK3CA GO:0030100| regulation of endocytosis ABL2;ABL1 GO:0072089| stem cell proliferation ABCB1 GO:0072358| cardiovascular system development ABL1 GO:0045332| phospholipid translocation ABCA1;ABCC1;ABCB1 GO:0030335| positive regulation of cell migration ACVR1;LYN GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C8;PRKAA1;CYP3A4;ABCA1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;ABL2;TNK2;ALK;HCK GO:0017144| drug metabolic process CYP2C8;NT5C2;CYP3A4 GO:0007420| brain development APAF1;BCR;ALK GO:1902715| ABL1 GO:0007165| signal transduction ABCC8;LYN;ABCC9;ACVR1B;NAE1;ABL2;ACVRL1;P2RY11;AKT1;ALK;CSNK2A1;AMHR2;TNK2;ARAF;MAP2K1;CSNK2B;ADCY1;BCR;PRKAA1;SRC GO:0010907| positive regulation of glucose metabolic process AKT1;SRC GO:0009725| response to hormone stimulus AKT1;LYN GO:1905555| ABL1 GO:1900182| SRC;AKT1 GO:1903351| ABL1 GO:0090135| actin filament branching ABL1 GO:0030900| forebrain development SRC;APAF1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0007050| cell cycle arrest MAP2K1;PRKAA1;ABL1 GO:0065009| regulation of molecular function ABCC9;CAMK2G GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0048536| spleen development ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABCA1;ABL1 GO:0048538| thymus development ABL1;MAP2K1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:0006979| response to oxidative stress ABL1;ABCC2;AKT1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:0006813| potassium ion transport ABCC9;ABCC8;CDK2 GO:1900026| ABL1 GO:2000773| negative regulation of cellular senescence ABL1 5912:[DB06616 DB05766] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0030900| forebrain development DRD2;SRC GO:0007165| signal transduction BCR;SRC;DRD2;MAP2K1;CHRM1;LYN;DRD3 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0006464| protein modification process CHRM1;ABL1 GO:0009636| response to toxin DRD2;LYN GO:0008283| cell proliferation CHRM1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;DRD2;MAP2K2 GO:0035556| intracellular signal transduction BCR;DRD2;SRC;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;DRD3;CHRM1;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0007399| nervous system development CHRM1;CAMK2G GO:0048678| response to axon injury DRD2;LYN GO:0042493| response to drug ABCB1;SRC;DRD2;DRD3;LYN 5913:[DB06616 DB00123] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways GO:0050727| regulation of inflammatory response SLC7A2;LYN;HCK GO:0016032| viral reproduction KARS;SRC;HCK;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;KARS GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;KARS;SRC GO:0006810| transport SLC7A1;ABCB1;SLC7A4;SLC7A2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;KARS GO:0000187| activation of MAPK activity MAP2K2;KARS;MAP2K1;MAP3K2 GO:0055085| transmembrane transport SLC22A4;SLC16A10;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;KARS;MAP2K2;MAP2K1;ABL1 5914:[DB06616 DB01812] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01812|Adenosine-3'-5'-Diphosphate HS3ST1;SULT2B1;RNASE2;SULT1A1;HS3ST3A1;RNASE1;SULT2A1;SULT1E1;NDST1;acpS;SULT1B1;topA common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;SULT2B1;MAP2K1 GO:0008202| steroid metabolic process SULT1E1;SULT2B1;CYP3A4;SULT1A1;CYP2C8;SULT1B1;SULT2A1 GO:0030900| forebrain development SRC;NDST1 GO:0006954| inflammatory response NDST1;LYN;HCK GO:0006805| xenobiotic metabolic process CYP2C8;SULT1B1;SULT1A1;CYP3A4 GO:0006935| chemotaxis MAP2K1;RNASE2 GO:0006629| lipid metabolic process SULT2B1;CYP3A4;SULT1A1;SULT2A1;SULT1B1 GO:0007507| heart development MAP2K1;NDST1 5915:[DB06616 DB07705] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07705|1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE CYP51A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP51A1;CYP2C8 GO:0006629| lipid metabolic process CYP51A1;CYP3A4 GO:0008202| steroid metabolic process CYP51A1;CYP3A4;CYP2C8 5916:[DB06616 DB08519] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08519|N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0008360| regulation of cell shape KDR;HCK GO:0008284| positive regulation of cell proliferation HCK;KDR;CDK2;LYN GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;KDR GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K1;KDR;HCK;MAP2K2;BCR;SRC;ABL1 GO:0007275| multicellular organismal development KDR;CDK2;CAMK2G GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0016032| viral reproduction KDR;HCK;SRC;LYN GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;KDR;MAP2K1 GO:0038083| ABL1;HCK;KDR;SRC;LYN GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR GO:0030154| cell differentiation CAMK2G;HCK;KDR GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;KDR;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;KDR;LYN GO:0030335| positive regulation of cell migration LYN;KDR GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;SRC;BCR;HCK;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;KDR;MAP2K2;SRC GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR 5917:[DB06616 DB04335] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04335|Inosine PNP;deoD;XDH;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;XDH GO:0042493| response to drug PNP;LYN;SRC;ABCB1 GO:0010629| negative regulation of gene expression XDH;MAP2K2;MAP2K1 GO:0001933| negative regulation of protein phosphorylation XDH;LYN 5918:[DB06616 DB09066] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09066|Corifollitropin alfa FSHR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;FSHR;SRC GO:0001545| primary ovarian follicle growth FSHR;SRC GO:0007165| signal transduction LYN;FSHR;BCR;SRC;MAP2K1 5919:[DB06616 DB03909] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways GO:0071456| cellular response to hypoxia SRC;PGK1 GO:0032869| cellular response to insulin stimulus INSR;SRC GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;INSR;MAP3K2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway INSR;LYN;HCK GO:0030335| positive regulation of cell migration LYN;INSR GO:0016310| phosphorylation CAMK2G;CDK2;LYN;PGK1;INSR;MAP3K2;PDXK;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0000187| activation of MAPK activity INSR;MAP3K2;MAP2K1;MAP2K2 GO:0008283| cell proliferation PDXK;SRC GO:0046777| protein autophosphorylation INSR;CAMK2G;LYN;BCR;SRC;HCK;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;LYN;INSR GO:0032148| activation of protein kinase B activity SRC;INSR GO:0035556| intracellular signal transduction BCR;SRC;INSR;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation INSR;LYN;CDK2;HCK GO:0001934| positive regulation of protein phosphorylation ABL1;INSR;LYN GO:0023014| signal transduction via phosphorylation event INSR;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;INSR;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0038083| INSR;LYN;SRC;HCK;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR GO:0006816| calcium ion transport CAMK2G;ATP2A1 5920:[DB06616 DB02152] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02152|K-252a MET;MAP2K1 common genes MAP2K1 common pathways GO:0035635| entry of bacterium into host cell SRC;MET GO:0006935| chemotaxis MAP2K1 GO:0021697| cerebellar cortex formation MAP2K1 GO:0007507| heart development MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;MAP2K2 GO:0050772| positive regulation of axonogenesis MAP2K1 GO:0001932| regulation of protein phosphorylation LYN;MAP2K1 GO:0048870| cell motility MAP2K1 GO:0048679| regulation of axon regeneration MAP2K1 GO:0060674| placenta blood vessel development MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation MET;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2 GO:0060324| face development MAP2K1 GO:0090398| cellular senescence MAP2K1 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1 GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;SRC GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2 GO:0060440| trachea formation MAP2K1 GO:0035897| proteolysis in other organism MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2 GO:0060425| lung morphogenesis MAP2K1 GO:0048538| thymus development MAP2K1;ABL1 GO:0030878| thyroid gland development MAP2K1 GO:0007165| signal transduction LYN;MET;MAP2K1;SRC;BCR GO:0007050| cell cycle arrest MAP2K1;ABL1 GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;MET;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;MET GO:1903800| MAP2K2;MAP2K1 GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;MET;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0006928| cellular component movement MAP2K1 GO:0090170| regulation of Golgi inheritance MAP2K2;MAP2K1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1 GO:0060711| labyrinthine layer development MAP2K1 GO:0030182| neuron differentiation MAP2K1;ABL1 GO:0008283| cell proliferation SRC;MET GO:0030216| keratinocyte differentiation MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;MAP2K2 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1 5921:[DB06616 DB03277] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03277|alpha-maltotriose AMY2B common genes common pathways 5922:[DB06616 DB04875] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04875|Pralnacasan CASP1 common genes common pathways GO:0006915| apoptotic process CASP1;ABL1 GO:0007165| signal transduction SRC;BCR;MAP2K1;CASP1;LYN GO:0050715| positive regulation of cytokine secretion SRC;CASP1 GO:0010506| regulation of autophagy CASP1;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CASP1 GO:0032496| response to lipopolysaccharide BCR;CASP1 GO:0051882| mitochondrial depolarization ABL1;CASP1 GO:0071260| cellular response to mechanical stimulus MAP3K2;CASP1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;CASP1;MAP3K2 GO:0050727| regulation of inflammatory response CASP1;LYN;HCK GO:0071222| cellular response to lipopolysaccharide CASP1;SRC;BCR;ABL1 5923:[DB06616 DB09215] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;HCK;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1;PTGS1;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;PTGS2;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0070542| response to fatty acid PTGS2;SRC 5924:[DB06616 DB08205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways GO:0006810| transport TTR;ABCB1 5925:[DB06616 DB05223] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:1903351| HDAC2;ABL1 GO:0034605| cellular response to heat LYN;HDAC2 GO:0070301| cellular response to hydrogen peroxide HDAC6;ABL1;HDAC2 GO:0010033| response to organic substance HDAC6;CDK2 GO:0008285| negative regulation of cell proliferation LYN;HDAC1;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;HDAC3;HDAC2;HDAC1;HDAC6 GO:0007596| blood coagulation HDAC2;HDAC1;LYN GO:0009636| response to toxin LYN;HDAC6 GO:0048668| collateral sprouting HDAC6;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;HDAC1;HDAC3;HDAC2 GO:0010634| positive regulation of epithelial cell migration SRC;HDAC6 GO:1901796| HDAC1;CDK2;HDAC2 GO:0008284| positive regulation of cell proliferation LYN;HDAC1;CDK2;HDAC2;HCK GO:0071300| cellular response to retinoic acid HDAC2;LYN GO:0043066| negative regulation of apoptotic process HDAC1;HDAC3;HDAC2;HCK;SRC GO:0071560| cellular response to transforming growth factor beta stimulus HDAC2;SRC GO:0034599| cellular response to oxidative stress ABL1;HDAC1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein HDAC1;LYN;HDAC2 GO:0032496| response to lipopolysaccharide HDAC1;HDAC2;BCR GO:0071498| cellular response to fluid shear stress HDAC3;SRC GO:0016032| viral reproduction HDAC1;LYN;SRC;HCK GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;HDAC3 GO:0006914| autophagy ABL1;HDAC6 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;HDAC1 GO:0042493| response to drug HDAC1;LYN;HDAC2;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent HDAC3;ABL1;HDAC2;HDAC1;HDAC6 GO:0010506| regulation of autophagy HDAC6;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;HDAC1;SRC;MAP2K2;MAP2K1;HDAC2 5926:[DB06616 DB03788] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03788|GC-24 THRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent THRB;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;THRB GO:0045892| negative regulation of transcription, DNA-dependent THRB;SRC 5927:[DB06616 DB11148] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11148|Butamben CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;BCHE;ORM1;ALB common genes common pathways GO:0055085| transmembrane transport CACNA1H;CACNA1S;CACNA1G;CACNA1B;KCNJ11;CACNA1C;CACNA1F;CACNA1I;ABCB1;CACNA1D;CACNA1A GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0006810| transport CACNG1;CACNB1;CACNB4;ABCB1;CACNA1I;CACNA1B;CACNB3 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CACNA1A;CACNA1C GO:0006813| potassium ion transport KCNJ10;KCNJ1;CDK2;KCNJ15;KCNJ11;KCNJ8;KCNJ12;KCNJ14 GO:0007165| signal transduction MAP2K1;CACNA1I;SRC;BCR;LYN GO:0042493| response to drug KCNJ11;LYN;BCHE;ABCB1;SRC GO:0014003| oligodendrocyte development LYN;KCNJ10 GO:0006816| calcium ion transport CACNA2D3;CACNG1;CACNB1;CACNA1F;CACNA1C;CACNA1A;CACNA1D;CACNA1I;CACNB4;CACNA2D2;CACNB3;CACNA1B;CACNA2D1;CACNB2;CAMK2G;CACNA1G;CACNA1S;CACNA1H GO:0006954| inflammatory response ORM1;LYN;HCK GO:0051924| regulation of calcium ion transport CACNA1B;CAMK2G;CACNA2D1 GO:0032496| response to lipopolysaccharide BCR;KCNJ8 GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0002576| platelet degranulation LYN;ORM1;ALB GO:0007507| heart development MAP2K1;CACNA1C;KCNJ8 5928:[DB06616 DB02678] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways GO:0006915| apoptotic process LGALS7;ABL1 5929:[DB06616 DB12698] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0007165| signal transduction CXCR4;MAP2K1;BCR;SRC;LYN;CCR5;CD4 GO:0002376| immune system process LYN;CD4;SRC;HCK GO:0007204| elevation of cytosolic calcium ion concentration CCR5;CXCR4;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway CD4;LYN;HCK GO:0031295| T cell costimulation CD4;LYN;SRC GO:0007411| axon guidance CXCR4;SRC GO:0006915| apoptotic process ABL1;CXCR4 GO:0000187| activation of MAPK activity MAP3K2;CXCR4;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CD4;MAP2K1;SRC;MAP2K2;ABL1 GO:0050690| regulation of defense response to virus by virus HCK;CD4 GO:0007155| cell adhesion CD4;ABL1;HCK;SRC GO:0009615| response to virus CXCR4;SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;CCR5 GO:0006935| chemotaxis CXCR4;MAP2K1;CCR5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD4;ABL1 GO:0002250| adaptive immune response CD4;LYN GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;CCR5 GO:0051924| regulation of calcium ion transport CD4;CAMK2G GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD4;LYN;SRC;ABL1 GO:0016032| viral reproduction HCK;SRC;CXCR4;CD4;LYN;CCR5 GO:0006816| calcium ion transport CCR5;CAMK2G GO:0006954| inflammatory response CXCR4;HCK;LYN;CCR5 GO:0001934| positive regulation of protein phosphorylation LYN;CD4;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CD4;CDK2;MAP2K1;MAP2K2;SRC 5930:[DB06616 DB01597] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0030336| negative regulation of cell migration DPEP1;BCR GO:0006915| apoptotic process ABL1;DPEP1 GO:0055085| transmembrane transport ABCB1;SLC22A8;SLC22A6 GO:0009636| response to toxin SLC22A8;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;DPEP1 GO:0043066| negative regulation of apoptotic process DPEP1;SRC;HCK GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;DPEP1 GO:0071732| cellular response to nitric oxide DPEP1;CDK2 5931:[DB06616 DB04048] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;PRDX2 GO:0042981| regulation of apoptotic process MAP3K2;PRDX2;MAP2K2;MAP2K1 GO:0034599| cellular response to oxidative stress ABL1;PRDX2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PRDX2 GO:0006979| response to oxidative stress PRDX2;ABL1 5932:[DB06616 DB00464] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00464|Sodium Tetradecyl Sulfate PROC;PROS1 common genes common pathways GO:0007596| blood coagulation PROS1;LYN;PROC GO:0002576| platelet degranulation PROS1;LYN GO:0043066| negative regulation of apoptotic process SRC;PROC;HCK GO:0050900| leukocyte migration PROC;SRC;LYN;PROS1 GO:0050728| negative regulation of inflammatory response PROC;BCR 5933:[DB06616 DB01709] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways GO:0042493| response to drug ABCB1;SRC;ENO3;LYN 5934:[DB06616 DB09526] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09526|Hydroquinone TYR;ALB common genes common pathways GO:0008283| cell proliferation SRC;TYR GO:0048538| thymus development MAP2K1;ABL1;TYR GO:0055114| oxidation-reduction process CYP2C8;TYR;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0002576| platelet degranulation ALB;LYN 5935:[DB06616 DB07456] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways GO:0035556| intracellular signal transduction CAMK2G;PDPK1;LYN;SRC;BCR GO:0043304| regulation of mast cell degranulation LYN;PDPK1 GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;PDPK1;CDK2 GO:0032148| activation of protein kinase B activity SRC;PDPK1 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;PDPK1 GO:0030036| actin cytoskeleton organization PDPK1;ABL1;BCR GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;PDPK1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0031295| T cell costimulation SRC;PDPK1;LYN GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;PDPK1;LYN;CDK2;CAMK2G;MAP3K2 GO:0030168| platelet activation SRC;LYN;PDPK1 GO:0006468| protein phosphorylation PDPK1;LYN;CDK2;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0032869| cellular response to insulin stimulus PDPK1;SRC GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;CAMK2G;LYN;PDPK1 GO:0016477| cell migration PDPK1;SRC GO:0038095| PDPK1;LYN GO:0018107| peptidyl-threonine phosphorylation MAP2K1;PDPK1;CAMK2G 5936:[DB06616 DB08467] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CRABP2;ABL1 GO:0007165| signal transduction LYN;SRC;CRABP2;BCR;MAP2K1 5937:[DB06616 DB04389] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04389|Ado-P-Ch2-P-Ps-Ado FHIT common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;FHIT GO:0006915| apoptotic process FHIT;ABL1 5938:[DB06616 DB08654] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08654|TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 5939:[DB06616 DB00043] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways GO:0006954| inflammatory response HCK;MS4A2;LYN GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;MS4A2 GO:0038095| MS4A2;LYN;FCER1A 5940:[DB06616 DB01194] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0006979| response to oxidative stress ABL1;CA3 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0010033| response to organic substance CDK2;CA2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0071498| cellular response to fluid shear stress CA2;SRC GO:0008209| androgen metabolic process CYP3A4 GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 5941:[DB06616 DB09343] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;TYMP GO:0006935| chemotaxis TYMP;MAP2K1 GO:0055085| transmembrane transport ABCB1;SLC47A1;SLC22A2 GO:0006855| drug transmembrane transport SLC22A2;SLC47A1;ABCB1 GO:0030154| cell differentiation TYMP;HCK;CAMK2G 5942:[DB06616 DB08608] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08608|4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE PDK2 common genes common pathways GO:0034614| cellular response to reactive oxygen species PDK2;SRC GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;PDK2;LYN;CDK2;MAP3K2 GO:0016310| phosphorylation CAMK2G;PDK2;LYN;CDK2;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 5943:[DB06616 DB00974] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0045580| regulation of T cell differentiation ADA;ABL1 GO:0009636| response to toxin LYN;PON3 GO:0050728| negative regulation of inflammatory response BCR;ADA GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP2C8;CYP19A1;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1;ADA GO:0007155| cell adhesion ADA;HCK;SRC;ABL1 GO:0042542| response to hydrogen peroxide SRC;ADA GO:0043066| negative regulation of apoptotic process ADA;HCK;SRC GO:0060065| uterus development SRC;CYP19A1 5944:[DB06616 DB00240] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0051301| cell division CDK2;NR3C1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0006915| apoptotic process ABL1;NR3C1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0007049| cell cycle NR3C1;CDK2;SRC GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0007165| signal transduction NR3C1;LYN;MAP2K1;BCR;SRC GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 5945:[DB06616 DB05282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05282|MCC AIFM1 common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;ABL1;AIFM1 GO:0071732| cellular response to nitric oxide CDK2;AIFM1 GO:0055114| oxidation-reduction process CYP3A4;AIFM1;CYP2C8 GO:0006915| apoptotic process ABL1;AIFM1 GO:0009636| response to toxin LYN;AIFM1 GO:0030182| neuron differentiation MAP2K1;AIFM1;ABL1 GO:0070301| cellular response to hydrogen peroxide AIFM1;ABL1 5946:[DB06616 DB05249] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05249|FavId CSF3R common genes common pathways GO:0007165| signal transduction LYN;CSF3R;BCR;SRC;MAP2K1 GO:0019221| cytokine-mediated signaling pathway CSF3R;HCK GO:0007155| cell adhesion CSF3R;ABL1;HCK;SRC 5947:[DB06616 DB08448] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 5948:[DB06616 DB03690] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PITPNA 5949:[DB06616 DB02850] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HPD 5950:[DB06616 DB03608] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03608|Diminazene PRDX5;PRSS1;AOC1 common genes common pathways GO:0034614| cellular response to reactive oxygen species PRDX5;SRC GO:0006915| apoptotic process PRDX5;ABL1 GO:0006979| response to oxidative stress PRDX5;ABL1 GO:0006954| inflammatory response LYN;PRDX5;HCK GO:0055114| oxidation-reduction process CYP2C8;PRDX5;CYP3A4;AOC1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PRDX5 GO:0042493| response to drug AOC1;LYN;ABCB1;SRC GO:0043066| negative regulation of apoptotic process PRDX5;SRC;HCK GO:0006805| xenobiotic metabolic process AOC1;CYP3A4;CYP2C8 GO:0034599| cellular response to oxidative stress PRDX5;ABL1 5951:[DB06616 DB06600] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 5952:[DB06616 DB06497] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06497|Aplaviroc CCR5 common genes common pathways GO:0007165| signal transduction LYN;CCR5;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration CCR5;ABL1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;CCR5 GO:0006935| chemotaxis MAP2K1;CCR5 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;CCR5 GO:0006954| inflammatory response CCR5;LYN;HCK GO:0016032| viral reproduction LYN;CCR5;HCK;SRC GO:0006816| calcium ion transport CAMK2G;CCR5 5953:[DB06616 DB08707] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08707|4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine PIM1 common genes common pathways GO:0007346| regulation of mitotic cell cycle MAP2K2;MAP2K1;PIM1;MAP3K2 GO:0007275| multicellular organismal development PIM1;CAMK2G;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;PIM1 GO:0008283| cell proliferation SRC;PIM1 GO:0006915| apoptotic process PIM1;ABL1 GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN;PIM1 GO:0007049| cell cycle CDK2;PIM1;SRC GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;PIM1;MAP3K2;CAMK2G;LYN;CDK2 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;PIM1 5954:[DB06616 DB07717] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0008283| cell proliferation AR;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0007165| signal transduction AR;MAP2K1;BCR;SRC;LYN GO:0006810| transport AR;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent AR;SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;AR GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0051259| protein oligomerization AR;CAMK2G 5955:[DB06616 DB00846] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0006915| apoptotic process NR3C1;ABL1 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;NR3C1 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0051301| cell division CDK2;NR3C1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 5956:[DB06616 DB04585] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04585|DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID ARG1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 GO:0043200| response to amino acid stimulus ARG1;LYN GO:0002376| immune system process ARG1;HCK;SRC;LYN GO:0043434| response to peptide hormone stimulus ARG1;LYN GO:0002250| adaptive immune response ARG1;LYN GO:0042493| response to drug ARG1;SRC;ABCB1;LYN GO:0045087| innate immune response LYN;SRC;HCK;ARG1;ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;ARG1;BCR;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC;ARG1 GO:0048678| response to axon injury ARG1;LYN GO:0032496| response to lipopolysaccharide BCR;ARG1 5957:[DB06616 DB01125] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01125|Anisindione GGCX common genes common pathways GO:0006464| protein modification process GGCX;ABL1 GO:0007596| blood coagulation GGCX;LYN 5958:[DB06616 DB02205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02205|6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GAPDHS;CYP2C8 5959:[DB06616 DB01606] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A6;SLC22A8;ABCB1 GO:0009636| response to toxin LYN;SLC22A8 5960:[DB06616 DB03191] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03191|3-Oxiran-2ylalanine MAT1A common genes common pathways 5961:[DB06616 DB06909] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways GO:0007165| signal transduction PDE4B;SRC;BCR;MAP2K1;LYN GO:0071222| cellular response to lipopolysaccharide PDE4B;ABL1;BCR;SRC GO:0050900| leukocyte migration SRC;PDE4B;LYN 5962:[DB06616 DB01009] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes CYP2C8 common pathways GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4;UGT1A1 GO:0070542| response to fatty acid PTGS2;SRC GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP3A4;CYP2C8 GO:0097267| CYP2C9;CYP2C8 GO:0007165| signal transduction CXCR1;LYN;SRC;BCR;MAP2K1 GO:0006979| response to oxidative stress ABL1;PTGS1;PTGS2 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0055085| transmembrane transport SLC22A8;SLC22A6;SLCO1A2;SLC22A7;SLC22A11;ABCB1;ABCC4 GO:0002933| CYP2C8;CYP3A4 GO:0009636| response to toxin LYN;SLC22A8 GO:0014070| response to organic cyclic compound ABCC4;PTGS2;UGT1A1;LYN GO:0010033| response to organic substance CDK2;UGT1A1;PTGS2;ABCC4 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1;PTGS2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;PTGS2;UGT1A1 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006082| organic acid metabolic process CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP2C9;CYP3A4 GO:0043066| negative regulation of apoptotic process PTGS2;ALB;HCK;SRC GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0002576| platelet degranulation LYN;ABCC4;ALB GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0006935| chemotaxis MAP2K1;CXCR1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0055114| oxidation-reduction process PTGS1;ABCC4;CYP2C8;PTGS2;CYP3A4;CYP2C9 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2C9 GO:0042493| response to drug ABCC4;SRC;ABCB1;PTGS2;UGT1A1;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS1;HCK;PTGS2;LYN 5963:[DB06616 DB12095] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;TPH1;TPH2;CYP3A4 GO:0031667| response to nutrient levels SRC;TPH2 5964:[DB06616 DB03233] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03233|Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways GO:0016310| phosphorylation LYN;CDK2;DTYMK;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0007049| cell cycle DTYMK;CDK2;SRC GO:0008283| cell proliferation DTYMK;SRC 5965:[DB06616 DB12498] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0006915| apoptotic process CXCR4;ABL1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1;CXCR4 GO:0007411| axon guidance SRC;CXCR4 GO:0007204| elevation of cytosolic calcium ion concentration CXCR4;ABL1 GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;CXCR4 GO:0006954| inflammatory response LYN;HCK;CXCR4 GO:0016032| viral reproduction CXCR4;SRC;HCK;LYN GO:0009615| response to virus CXCR4;SRC GO:0006935| chemotaxis CXCR4;MAP2K1 5966:[DB06616 DB07388] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07388|ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2;NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4;CYP2C8;NOS3 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 GO:0043542| endothelial cell migration ABL1;NOS3 GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;NOS3 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NOS2 GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;LYN 5967:[DB06616 DB00827] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 5968:[DB06616 DB11967] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes MAP2K2 common pathways GO:0009743| response to carbohydrate stimulus IL1B;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;IL6;LYN GO:0019221| cytokine-mediated signaling pathway HCK;IL6;IL1B GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0000165| MAPKKK cascade IL1B;MAP2K1;MAP3K1;MAP2K2;TNF;CAMK2G GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2 GO:0006954| inflammatory response TNF;LYN;HCK;IL6;IL1B GO:0023014| signal transduction via phosphorylation event LYN;MAP3K1 GO:0050900| leukocyte migration SRC;IL1B;TNF;LYN GO:0001934| positive regulation of protein phosphorylation LYN;TNF;IL1B;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A4;CYP1A2 GO:0042493| response to drug LYN;UGT1A1;CYP1A2;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression TNF;MAP2K2;MAP2K1 GO:0007346| regulation of mitotic cell cycle MAP2K2;MAP3K1;MAP2K1;MAP3K2 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;SRC;MAP2K2;MAP2K1;IL6;TNF;CDK2;MAP3K2 GO:0035897| proteolysis in other organism MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TNF GO:0042981| regulation of apoptotic process MAP2K2;MAP3K1;MAP2K1;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0071260| cellular response to mechanical stimulus MAP3K1;IL1B;MAP3K2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0043065| positive regulation of apoptotic process IL6;SRC;ABL1;TNF GO:0050727| regulation of inflammatory response HCK;TNF;LYN GO:0008284| positive regulation of cell proliferation IL6;HCK;IL1B;LYN;CDK2 GO:0071222| cellular response to lipopolysaccharide TNF;IL6;SRC;BCR;ABL1 GO:0009615| response to virus TNF;SRC GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP1A2 GO:0043066| negative regulation of apoptotic process SRC;HCK;IL6 GO:0031663| lipopolysaccharide-mediated signaling pathway IL1B;HCK;TNF;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IL1B;ABL1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL6 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0042127| regulation of cell proliferation TNF;SRC;ABL1 GO:0046483| heterocycle metabolic process CYP2C19;CYP1A2;UGT1A1;CYP3A4 GO:0001932| regulation of protein phosphorylation MAP2K1;TNF;LYN GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;IL1B;BCR GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP1A2 GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0070301| cellular response to hydrogen peroxide IL6;ABL1 GO:0043407| negative regulation of MAP kinase activity LYN;IL1B GO:0090170| regulation of Golgi inheritance MAP2K1;MAP2K2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CDK2;TNF GO:0008285| negative regulation of cell proliferation IL1B;MAP2K1;IL6;LYN GO:0050766| positive regulation of phagocytosis TNF;BCR;IL1B GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1 GO:0036289| MAP2K2 GO:0010628| positive regulation of gene expression IL1B;SRC;MAP2K1;IL6;TNF GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;TNF GO:0000187| activation of MAPK activity TNF;MAP3K2;IL1B;MAP2K2;MAP2K1 GO:0006915| apoptotic process IL1B;ABL1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;MAP2K2 GO:0031175| neuron projection development IL6;LYN GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNF GO:0038095| LYN;MAP3K1 GO:0014070| response to organic cyclic compound LYN;CYP1A2;UGT1A1 GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;IL1B GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C19;CYP2C8 GO:0097267| CYP1A2;CYP2C19;CYP2C8 GO:0051222| positive regulation of protein transport SRC;TNF GO:0070372| regulation of ERK1 and ERK2 cascade LYN;IL1B GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0006468| protein phosphorylation ABL1;MAP2K1;MAP3K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:1903800| MAP2K2;MAP2K1 GO:0030168| platelet activation SRC;IL6;LYN GO:0000186| activation of MAPKK activity MAP3K2;MAP3K1 GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0016310| phosphorylation MAP2K1;MAP3K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0030335| positive regulation of cell migration IL1B;LYN GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP1A2;CYP3A4 5969:[DB06616 DB00629] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;CDK2;LYN GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2B GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0000187| activation of MAPK activity MAP3K2;ADRA2B;MAP2K2;MAP2K1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0007165| signal transduction SRC;BCR;MAP2K1;ADRA2A;LYN;ADRA2B GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0030168| platelet activation SRC;ADRA2A;LYN;ADRA2B 5970:[DB06616 DB01632] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0016032| viral reproduction LYN;UCKL1;HCK;SRC GO:0032869| cellular response to insulin stimulus SRC;APRT GO:0016310| phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;UCKL1;HCK;CAMK2G;LYN;CDK2;MAP3K2 5971:[DB06616 DB02821] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02821|Canaline OAT common genes common pathways 5972:[DB06616 DB04818] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04818|Iproniazid MAOB;CYP2D6;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0042493| response to drug MAOB;LYN;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process MAOB;CYP2C9;CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0009636| response to toxin MAOB;LYN 5973:[DB06616 DB02207] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02207|7-Nitroindazole NOS3;NOS2 common genes common pathways GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;NOS2 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;NOS3 GO:0043542| endothelial cell migration NOS3;ABL1 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC GO:0055114| oxidation-reduction process NOS3;CYP2C8;NOS2;CYP3A4 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NOS2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;NOS3 5974:[DB06616 DB03731] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03731|S-2-(Boronoethyl)-L-Cysteine ARG1;ARG2 common genes common pathways GO:0002376| immune system process LYN;SRC;ARG2;HCK;ARG1 GO:0043434| response to peptide hormone stimulus LYN;ARG1 GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 GO:0043200| response to amino acid stimulus ARG1;LYN GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;ARG1 GO:0045087| innate immune response LYN;ARG1;ABL1;SRC;ARG2;HCK GO:0032496| response to lipopolysaccharide ARG1;BCR GO:0048678| response to axon injury ARG1;LYN GO:0002250| adaptive immune response LYN;ARG1;ARG2 GO:0042493| response to drug LYN;ABCB1;SRC;ARG1 5975:[DB06616 DB11294] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11294|Coccidioides immitis spherule HLA-A;HLA-A;HLA-B common genes common pathways GO:0045087| innate immune response HCK;SRC;ABL1;HLA-B;LYN GO:0016032| viral reproduction LYN;HLA-B;HLA-A;SRC;HCK GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;HLA-B;HLA-A;HCK GO:0002376| immune system process SRC;HCK;HLA-A;HLA-B;LYN 5976:[DB06616 DB08800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08800|Chloropyramine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;LYN;BCR;SRC;MAP2K1 GO:0006954| inflammatory response LYN;HRH1;HCK GO:0043114| regulation of vascular permeability HRH1;BCR;SRC 5977:[DB06616 DB07239] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways GO:0007155| cell adhesion ABL1;HCK;SRC;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CDK2;LYN;HCK GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation SRC;LYN;DPP4 5978:[DB06616 DB08384] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways GO:0007165| signal transduction PDE10A;MAP2K1;BCR;SRC;LYN 5979:[DB06616 DB05398] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05398|C31G CD9 common genes common pathways GO:0014003| oligodendrocyte development CD9;LYN GO:0007155| cell adhesion HCK;SRC;CD9;ABL1 GO:0002576| platelet degranulation LYN;CD9 GO:0008285| negative regulation of cell proliferation MAP2K1;CD9;LYN GO:0006928| cellular component movement MAP2K1;CD9 GO:0007420| brain development CD9;BCR GO:0030168| platelet activation SRC;CD9;LYN 5980:[DB06616 DB01277] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0042981| regulation of apoptotic process IGF2R;MAP3K2;MAP2K2;IGFBP3;MAP2K1 GO:0032148| activation of protein kinase B activity SRC;INSR GO:0008284| positive regulation of cell proliferation HCK;INSR;IGF1R;LYN;CDK2 GO:0043065| positive regulation of apoptotic process IGFBP3;SRC;ABL1;IGF2R GO:0043066| negative regulation of apoptotic process IGF1R;HCK;SRC GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G;INSR GO:0018108| peptidyl-tyrosine phosphorylation LYN;INSR;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0001933| negative regulation of protein phosphorylation IGFBP3;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR GO:0023014| signal transduction via phosphorylation event INSR;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;INSR;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;INSR GO:0038083| LYN;IGF1R;INSR;ABL1;SRC;HCK GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;INSR;MAP3K2 GO:0007165| signal transduction IGF1R;LYN;IGF2R;SRC;BCR;MAP2K1 GO:0032869| cellular response to insulin stimulus SRC;INSR GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;IGFBP3;SRC;CDK2;LYN;CAMK2G;INSR;MAP3K2;IGF1R GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;INSR;MAP3K2;IGF1R GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;INSR;IGF1R;HCK GO:0030335| positive regulation of cell migration LYN;IGF1R;INSR GO:0008285| negative regulation of cell proliferation IGFBP3;MAP2K1;LYN GO:0046777| protein autophosphorylation CAMK2G;LYN;IGF1R;INSR;ABL1;SRC;BCR;HCK GO:0009791| post-embryonic development IGF2R;ABL1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;INSR;MAP3K2 GO:0006915| apoptotic process IGFBP3;ABL1 5981:[DB06616 DB00461] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0006979| response to oxidative stress ABL1;MPO;PTGS1;PTGS2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0070542| response to fatty acid PTGS2;SRC GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0034605| cellular response to heat PTGS2;LYN GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0014070| response to organic cyclic compound LYN;PTGS2;CYP1A2 GO:0043066| negative regulation of apoptotic process SRC;MPO;HCK;PTGS2 GO:0009612| response to mechanical stimulus MPO;SRC GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8;PTGS1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP3A4;PTGS1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;MPO;CYP1A2;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1;PTGS2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006954| inflammatory response LYN;PTGS2;HCK;PTGS1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;MPO;PTGS1;CYP3A4;PTGS2;CYP1A2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC 5982:[DB06616 DB02746] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0016032| viral reproduction LYN;RXRA;SRC;HCK GO:0050728| negative regulation of inflammatory response PPARD;PPARA;BCR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARA;PPARG;RXRA;CDK2;MAP3K2;PPARD;ESR2;SRC;MAP2K2;MAP2K1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;PGR;MAP2K2 GO:0042493| response to drug LYN;PPARG;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent PGR;ESR2;ABL1;RXRG;PPARD;RXRB;RXRA;PPARG;ESR1;PPARA GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0060065| uterus development SRC;ESR1 GO:0043066| negative regulation of apoptotic process PPARD;SRC;HCK GO:0009612| response to mechanical stimulus SRC;PPARG GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0043065| positive regulation of apoptotic process PPARG;SRC;ABL1 GO:0071222| cellular response to lipopolysaccharide PPARD;ABL1;SRC;BCR GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC;ESR1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PPARD GO:0006629| lipid metabolic process PPARD;CYP3A4;PPARA;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0007507| heart development MAP2K1;PPARD;RXRA;PPARG;PPARA GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;PPARD;RXRA;CDK2;PPARA;ESR1;PPARG GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0042127| regulation of cell proliferation PPARD;ABL1;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;PPARD GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0010033| response to organic substance PPARG;CDK2;PPARD GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD;SRC GO:0014070| response to organic cyclic compound LYN;PPARG GO:0008283| cell proliferation PPARD;SRC GO:0006915| apoptotic process ABL1;PPARD GO:0032868| response to insulin stimulus LYN;PPARA GO:0055085| transmembrane transport ABCB1;SLCO2B1 GO:0007165| signal transduction MAP2K1;SRC;PGR;BCR;ESR2;LYN;ESR1;PPARG GO:0030154| cell differentiation HCK;PPARD;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0071456| cellular response to hypoxia PPARD;SRC GO:0050847| progesterone receptor signaling pathway SRC;PGR GO:0032869| cellular response to insulin stimulus PPARG;SRC 5983:[DB06616 DB02175] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02175|Malonic acid panD;SRC;SNRPA common genes SRC common pathways GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1 GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;BCR;SRC;HCK GO:0051895| negative regulation of focal adhesion assembly SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0071456| cellular response to hypoxia SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0032463| negative regulation of protein homooligomerization SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0042493| response to drug LYN;SRC;ABCB1 GO:0038083| HCK;SRC;ABL1;LYN GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration SRC;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction LYN;SRC;HCK GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0038096| LYN;SRC;HCK;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0038128| SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0086098| SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G GO:0071398| cellular response to fatty acid SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0060065| uterus development SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0009615| response to virus SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion HCK;SRC;ABL1 5984:[DB06616 DB02118] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02118|CP-271485 MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;MMP12 GO:0010628| positive regulation of gene expression MMP12;SRC;MAP2K1 5985:[DB06616 DB00892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways GO:0042493| response to drug LYN;BCHE;SRC;ABCB1 GO:0055085| transmembrane transport SCN10A;ABCB1 GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 5986:[DB06616 DB02558] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways 5987:[DB06616 DB08530] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;DPP4;LYN GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0007155| cell adhesion ABL1;HCK;SRC;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 5988:[DB06616 DB13925] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways GO:0030900| forebrain development SSTR2;SRC GO:0007165| signal transduction LYN;SSTR2;MAP2K1;SRC;BCR GO:0008285| negative regulation of cell proliferation LYN;SSTR2;MAP2K1 5989:[DB06616 DB14060] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14060|NS-398 PTGS2 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS2 GO:0006954| inflammatory response HCK;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0014070| response to organic cyclic compound PTGS2;LYN 5990:[DB06616 DB07468] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07468|(3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways GO:0008360| regulation of cell shape MYH14;HCK 5991:[DB06616 DB01180] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01180|Rescinnamine ACE common genes common pathways 5992:[DB06616 DB00310] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00310|Chlorthalidone SLC12A1 common genes common pathways GO:0055085| transmembrane transport SLC12A1;ABCB1 GO:0006813| potassium ion transport CDK2;SLC12A1 GO:0006810| transport ABCB1;SLC12A1 5993:[DB06616 DB02170] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02170|1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One CSNK2A1 common genes common pathways GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CSNK2A1;CDK2;LYN;CAMK2G GO:0006468| protein phosphorylation CSNK2A1;MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;CSNK2A1 GO:0006915| apoptotic process CSNK2A1;ABL1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CSNK2A1 GO:0007049| cell cycle SRC;CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CSNK2A1 GO:1901796| CDK2;CSNK2A1 GO:0016236| macroautophagy SRC;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 5994:[DB06616 DB00913] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00913|Anileridine OPRM1 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ABL1;SRC;MAP2K2;MAP2K1 GO:0007165| signal transduction MAP2K1;SRC;BCR;OPRM1;LYN GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0032496| response to lipopolysaccharide BCR;OPRM1 5995:[DB06616 DB08848] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08848|Guvacine SLC6A13;SLC6A1;SLC6A11;SLC6A12 common genes common pathways GO:0010033| response to organic substance CDK2;SLC6A1 GO:0055085| transmembrane transport SLC6A1;SLC6A13;SLC6A11;SLC6A12;ABCB1 GO:0009636| response to toxin SLC6A1;LYN GO:0014070| response to organic cyclic compound SLC6A1;LYN GO:0007420| brain development SLC6A11;BCR GO:0006810| transport SLC6A12;ABCB1;SLC6A1 GO:0042493| response to drug SLC6A11;SRC;ABCB1;LYN 5996:[DB06616 DB02512] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways GO:0002576| platelet degranulation LYN;ALDOA GO:0008360| regulation of cell shape HCK;ALDOA 5997:[DB06616 DB12589] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12589|Dacetuzumab CD40 common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;CD40 GO:0042100| B cell proliferation CD40;ABL1 GO:0002376| immune system process LYN;CD40;HCK;SRC GO:0043547| positive regulation of GTPase activity BCR;CD40 GO:0030168| platelet activation SRC;LYN;CD40 GO:0002768| immune response-regulating cell surface receptor signaling pathway CD40;LYN GO:0006954| inflammatory response HCK;LYN;CD40 GO:0031667| response to nutrient levels SRC;CD40 GO:0001934| positive regulation of protein phosphorylation LYN;CD40;ABL1 GO:0071222| cellular response to lipopolysaccharide CD40;BCR;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;CD40 GO:0042127| regulation of cell proliferation ABL1;SRC;CD40 GO:0032496| response to lipopolysaccharide CD40;BCR GO:0007275| multicellular organismal development CAMK2G;CDK2;CD40 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein CD40;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD40;ABL1 5998:[DB06616 DB07106] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways GO:0007420| brain development BCR;HNMT 5999:[DB06616 DB09097] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways GO:0009636| response to toxin DRD2;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;DRD2;MAP2K2;MAP2K1;ABL1 GO:0010628| positive regulation of gene expression DRD1;SRC;MAP2K1 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0030335| positive regulation of cell migration DRD1;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0030900| forebrain development DRD2;SRC GO:1903351| ABL1;DRD1 GO:0007165| signal transduction DRD5;MAP2K1;DRD2;SRC;BCR;DRD1;LYN GO:0042493| response to drug LYN;DRD1;DRD2;SRC;ABCB1 GO:0001932| regulation of protein phosphorylation LYN;MAP2K1;DRD1 GO:0048678| response to axon injury LYN;DRD2 GO:0035556| intracellular signal transduction DRD2;SRC;BCR;LYN;CAMK2G 6000:[DB06616 DB08629] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08629|N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 6001:[DB06616 DB04886] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04886|Calanolide A CYP3A4 common genes CYP3A4 common pathways GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 6002:[DB06616 DB05075] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0002250| adaptive immune response LYN;CSK GO:0001817| regulation of cytokine production CSK;LYN GO:0016032| viral reproduction LYN;SRC;HCK;KDR GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0001934| positive regulation of protein phosphorylation ABL1;KDR;FLT4;LYN GO:0034332| adherens junction organization SRC;CSK GO:0007173| epidermal growth factor receptor signaling pathway ABL1;CSK;SRC GO:0010629| negative regulation of gene expression MAP2K1;KDR;MAP2K2 GO:0038083| LYN;ABL1;CSK;SRC;KDR;HCK GO:0008360| regulation of cell shape HCK;KDR GO:0045087| innate immune response LYN;CSK;ABL1;HCK;SRC GO:0043066| negative regulation of apoptotic process SRC;KDR;HCK;FLT4 GO:0048010| vascular endothelial growth factor receptor signaling pathway FLT4;FLT1;SRC;KDR GO:0008284| positive regulation of cell proliferation FLT1;CDK2;LYN;FLT4;KDR;HCK GO:0006935| chemotaxis MAP2K1;FLT1 GO:0018108| peptidyl-tyrosine phosphorylation HCK;KDR;MAP2K1;SRC;BCR;MAP2K2;ABL1;FLT1;FLT4;LYN GO:0007275| multicellular organismal development KDR;CAMK2G;CDK2;FLT1 GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0042127| regulation of cell proliferation ABL1;CSK;SRC GO:0008285| negative regulation of cell proliferation LYN;CSK;MAP2K1 GO:0071375| cellular response to peptide hormone stimulus CSK;SRC GO:0043406| positive regulation of MAP kinase activity SRC;CSK;FLT1 GO:0046777| protein autophosphorylation CSK;ABL1;KDR;HCK;BCR;SRC;LYN;FLT4;CAMK2G;FLT1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FLT4;KDR;MAP2K1;MAP2K2;SRC;ABL1 GO:0016477| cell migration FLT1;SRC GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;CSK;LYN GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0007420| brain development CSK;BCR GO:0002376| immune system process CSK;SRC;HCK;LYN GO:0030154| cell differentiation CSK;KDR;HCK;CAMK2G;FLT1 GO:0006468| protein phosphorylation MAP3K2;FLT1;LYN;CDK2;FLT4;CAMK2G;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC;CSK;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT1;FLT4;LYN;HCK;KDR;CSK GO:0030335| positive regulation of cell migration KDR;LYN;FLT1 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;FLT1;LYN GO:0031295| T cell costimulation CSK;SRC;LYN GO:0016310| phosphorylation CDK2;LYN;FLT4;CAMK2G;MAP3K2;FLT1;CSK;ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0007417| central nervous system development SRC;CSK;LYN GO:0010595| positive regulation of endothelial cell migration KDR;ABL1;FLT4 6003:[DB06616 DB04736] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PGLYRP3 GO:0002376| immune system process SRC;HCK;PGLYRP3;LYN 6004:[DB06616 DB05364] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05364|ROX-888 CCL3 common genes common pathways GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;CCL3 GO:0006954| inflammatory response LYN;CCL3;HCK GO:0006816| calcium ion transport CCL3;CAMK2G GO:0000165| MAPKKK cascade CCL3;MAP2K1;MAP2K2;CAMK2G GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CCL3 GO:0006935| chemotaxis MAP2K1;CCL3 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;CCL3 GO:0008360| regulation of cell shape CCL3;HCK GO:0009636| response to toxin CCL3;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;CCL3 GO:0010628| positive regulation of gene expression CCL3;MAP2K1;SRC GO:0030335| positive regulation of cell migration LYN;CCL3 GO:0043547| positive regulation of GTPase activity CCL3;BCR GO:0006887| exocytosis CCL3;HCK 6005:[DB06616 DB05095] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0042493| response to drug LYN;PTGS2;SRC;ABCB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0006954| inflammatory response PTGS2;LYN;HCK GO:0071498| cellular response to fluid shear stress SRC;PTGS2 6006:[DB06616 DB00067] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0007165| signal transduction SRC;BCR;MAP2K1;AVPR2;AVPR1B;AVPR1A;LYN GO:0006810| transport ABCB1;ABCC2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AVPR1B;AVPR1A GO:0010628| positive regulation of gene expression AVPR2;MAP2K1;SRC GO:0010033| response to organic substance AVPR1A;CDK2 GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0071222| cellular response to lipopolysaccharide ABL1;ABCC2;BCR;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;AVPR1A;AVPR2;HCK GO:0032496| response to lipopolysaccharide BCR;ABCC2 GO:0042493| response to drug LYN;ABCC2;ABCB1;SRC 6007:[DB06616 DB03216] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03216|(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine AHCY common genes common pathways 6008:[DB06616 DB00983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP3A4;CYP2A6 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4;CYP2C9;CYP2A6 GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2A6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1;ADRB2 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP2C19;CYP2A6;CYP3A4;CYP2C9 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0007165| signal transduction ADRB3;ADRB1;SRC;BCR;MAP2K1;LYN;ADRB2 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP2A6 GO:0097267| CYP2C9;CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0045453| bone resorption SRC;ADRB2 6009:[DB06616 DB05204] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05204|XL418 BTK common genes common pathways GO:0002376| immune system process LYN;SRC;BTK;HCK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;BTK;HCK GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;BTK;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;BTK;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0030889| negative regulation of B cell proliferation LYN;BTK GO:0034614| cellular response to reactive oxygen species BTK;SRC GO:0046777| protein autophosphorylation ABL1;BCR;SRC;BTK;HCK;CAMK2G;LYN GO:0050853| B cell receptor signaling pathway BTK;ABL1;LYN GO:0010033| response to organic substance CDK2;BTK GO:0038095| BTK;LYN GO:0006915| apoptotic process BTK;ABL1 GO:0002902| regulation of B cell apoptosis LYN;BTK GO:0035556| intracellular signal transduction LYN;CAMK2G;BTK;SRC;BCR GO:0045087| innate immune response SRC;HCK;BTK;ABL1;LYN GO:0042127| regulation of cell proliferation ABL1;BTK;SRC GO:0018108| peptidyl-tyrosine phosphorylation BCR;MAP2K2;SRC;BTK;MAP2K1;HCK;ABL1;LYN GO:0007498| mesoderm development HCK;BTK GO:0002553| histamine secretion by mast cell LYN;BTK GO:0002250| adaptive immune response LYN;BTK GO:0006355| regulation of transcription, DNA-dependent BTK;ABL1 GO:0038083| LYN;ABL1;SRC;BTK;HCK 6010:[DB06616 DB02902] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;SULT1E1;CYP3A4 6011:[DB06616 DB07116] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07116|1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE UNG common genes common pathways GO:0016032| viral reproduction LYN;UNG;HCK;SRC GO:0006974| response to DNA damage stimulus UNG;LYN;CDK2;ABL1 GO:0006281| DNA repair CDK2;UNG;ABL1 GO:0043066| negative regulation of apoptotic process SRC;HCK;UNG 6012:[DB06616 DB00789] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00789|Gadopentetic acid PGD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PGD;CYP2C8 6013:[DB06616 DB07646] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0043065| positive regulation of apoptotic process SRC;ABL1;DHODH GO:0042493| response to drug ABCB1;SRC;DHODH;LYN GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHODH 6014:[DB06616 DB04599] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;DRD2;MAP2K1;ABL1;HTR2A GO:0009636| response to toxin LYN;DRD2 GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0006810| transport ABCB1;GRIA3 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0030900| forebrain development SRC;DRD2 GO:0007165| signal transduction BCR;SRC;DRD2;GRIA2;MAP2K1;LYN;HTR2A GO:0042493| response to drug DRD2;SRC;ABCB1;LYN;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;ABL1;SRC GO:0016032| viral reproduction HTR2A;LYN;HCK;SRC GO:0048678| response to axon injury LYN;DRD2 GO:0035556| intracellular signal transduction BCR;DRD2;SRC;CAMK2G;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK 6015:[DB06616 DB01667] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LYN;PNP;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 6016:[DB06616 DB00282] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00282|Pamidronate FDPS common genes common pathways GO:0016032| viral reproduction SRC;HCK;FDPS;LYN GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP2C8;CYP3A4 6017:[DB06616 DB06831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06831|2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE PIK3CG;PIK3CD common genes common pathways GO:0016310| phosphorylation PIK3CG;CAMK2G;LYN;CDK2;PIK3CD;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0030335| positive regulation of cell migration LYN;PIK3CD GO:0007204| elevation of cytosolic calcium ion concentration PIK3CG;ABL1 GO:0030154| cell differentiation CAMK2G;PIK3CD;HCK GO:0006468| protein phosphorylation CAMK2G;PIK3CG;CDK2;LYN;PIK3CD;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0030168| platelet activation PIK3CD;PIK3CG;LYN;SRC GO:0002376| immune system process SRC;HCK;PIK3CG;LYN;PIK3CD GO:0007165| signal transduction PIK3CD;LYN;MAP2K1;SRC;BCR GO:0033628| regulation of cell adhesion mediated by integrin LYN;PIK3CG GO:0050853| B cell receptor signaling pathway ABL1;LYN;PIK3CD GO:0010628| positive regulation of gene expression PIK3CD;SRC;MAP2K1 GO:0007411| axon guidance SRC;PIK3CD GO:0043406| positive regulation of MAP kinase activity PIK3CG;SRC GO:0001932| regulation of protein phosphorylation LYN;PIK3CG;MAP2K1 GO:0006935| chemotaxis MAP2K1;PIK3CD;PIK3CG GO:0006897| endocytosis ABL1;PIK3CG GO:0045087| innate immune response PIK3CG;LYN;PIK3CD;ABL1;SRC;HCK GO:0006954| inflammatory response HCK;PIK3CG;LYN;PIK3CD GO:0002250| adaptive immune response PIK3CD;LYN;PIK3CG GO:0051897| positive regulation of protein kinase B signaling cascade SRC;PIK3CG;PIK3CD 6018:[DB06616 DB00935] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0042493| response to drug ABCB1;ADRA1A;SRC;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA1D;ADRA2A;HCK GO:0035556| intracellular signal transduction ADRA1B;BCR;ADRA1A;SRC;LYN;CAMK2G GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2C;ADRA2B GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0007275| multicellular organismal development CDK2;CAMK2G;ADRA1D;ADRA1B GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A GO:0008283| cell proliferation ADRA1D;ADRA1B;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;ADRA1A;MAP2K2;MAP2K1 GO:0000187| activation of MAPK activity MAP3K2;ADRA2B;MAP2K1;MAP2K2 GO:0006915| apoptotic process ABL1;ADRA1A GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction BCR;ADRA1A;SRC;MAP2K1;ADRA1B;ADRA2A;ADRA1D;ADRA2C;LYN;ADRA2B GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1B;ABL1;ADRA1D GO:0030168| platelet activation LYN;ADRA2B;ADRA2C;ADRA2A;SRC 6019:[DB06616 DB05016] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A8;SLCO1B3 GO:0009636| response to toxin SLC22A8;LYN 6020:[DB06616 DB01341] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways GO:0006810| transport GABRA1;ABCB1 6021:[DB06616 DB02183] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;HINT1 GO:0006915| apoptotic process ABL1;HINT1 GO:0006355| regulation of transcription, DNA-dependent ABL1;HINT1 6022:[DB06616 DB00129] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 GO:0032868| response to insulin stimulus LYN;OTC GO:0043200| response to amino acid stimulus LYN;ARG1 GO:0002376| immune system process SRC;HCK;ARG2;ARG1;LYN GO:0006810| transport ABCB1;SLC7A1;SLC7A2;SLC7A4 GO:0043434| response to peptide hormone stimulus ARG1;LYN GO:0002250| adaptive immune response ARG1;ARG2;LYN GO:0031667| response to nutrient levels OTC;SRC GO:0042493| response to drug LYN;ARG1;OTC;SRC;ABCB1 GO:0045087| innate immune response HCK;ARG2;SRC;ABL1;ARG1;LYN GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;SLC7A2 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;ARG1 GO:0007275| multicellular organismal development CDK2;CAMK2G;GATM GO:0048678| response to axon injury LYN;ARG1 GO:0032496| response to lipopolysaccharide BCR;ARG1 6023:[DB06616 DB05467] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05467|R667 RARG common genes common pathways GO:0060324| face development RARG;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;RARG GO:0043066| negative regulation of apoptotic process RARG;HCK;SRC GO:0071300| cellular response to retinoic acid LYN;RARG GO:0008284| positive regulation of cell proliferation CDK2;LYN;RARG;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;RARG GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;RARG GO:0010628| positive regulation of gene expression MAP2K1;SRC;RARG GO:0001843| neural tube closure ABL1;RARG 6024:[DB06616 DB00519] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0009636| response to toxin LYN;CES1 GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A2;SLC15A1 6025:[DB06616 DB03397] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03397|Uridine-Diphosphate-N-Acetylglucosamine glmU;UAP1;murA;GALE;glmU;EXTL2;MGAT1 common genes common pathways 6026:[DB06616 DB01908] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01908|RU85493 SRC common genes SRC common pathways GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response LYN;SRC;HCK;ABL1 GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G GO:0071398| cellular response to fatty acid SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0035635| entry of bacterium into host cell SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071498| cellular response to fluid shear stress SRC GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0038096| LYN;ABL1;SRC;HCK GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0016032| viral reproduction SRC;HCK;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0034332| adherens junction organization SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0050900| leukocyte migration LYN;SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0042493| response to drug ABCB1;SRC;LYN GO:0038083| HCK;SRC;ABL1;LYN GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0060491| regulation of cell projection assembly SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;LYN;CAMK2G GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0045785| positive regulation of cell adhesion SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC 6027:[DB06616 DB06962] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06962|(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone TPSB2 common genes common pathways 6028:[DB06616 DB06928] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways 6029:[DB06616 DB06376] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06376|CHGN111 CLK1 common genes common pathways GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CLK1;CAMK2G GO:0008283| cell proliferation SRC;CLK1 GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN;CLK1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;CDK2;CAMK2G;CLK1;MAP3K2 GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CLK1;CDK2;LYN;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CLK1 GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G;CLK1 6030:[DB06616 DB12248] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12248|Tulobuterol ADRB2 common genes common pathways GO:0045453| bone resorption SRC;ADRB2 GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;ADRB2 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 6031:[DB06616 DB02518] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02518|N-Acetylalanine AKR1B1 common genes common pathways GO:0010033| response to organic substance CDK2;AKR1B1 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 6032:[DB06616 DB01084] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01084|Emedastine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;LYN;HCK GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;HRH1 6033:[DB06616 DB11327] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0006954| inflammatory response HCK;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NOS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process CYP3A4;NOS2;PTGS2;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;PTGS2;HCK GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0032496| response to lipopolysaccharide BCR;NOS2;PTGS2 GO:0042127| regulation of cell proliferation SRC;ABL1;PTGS2;NOS2 GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC 6034:[DB06616 DB06083] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06083|Tapinarof IL12B;IL2;IL6;CXCL8 common genes common pathways GO:0002376| immune system process LYN;IL2;HCK;SRC GO:0065009| regulation of molecular function IL2;CAMK2G GO:0007050| cell cycle arrest ABL1;MAP2K1;IL12B;CXCL8 GO:0007165| signal transduction LYN;MAP2K1;CXCL8;BCR;SRC GO:0030168| platelet activation LYN;IL6;SRC GO:0007204| elevation of cytosolic calcium ion concentration IL2;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;IL6;SRC GO:0006928| cellular component movement MAP2K1;CXCL8 GO:0010033| response to organic substance CDK2;IL12B GO:0008285| negative regulation of cell proliferation IL6;MAP2K1;CXCL8;LYN GO:0070301| cellular response to hydrogen peroxide ABL1;IL6 GO:0016477| cell migration SRC;IL12B GO:0031175| neuron projection development LYN;IL6 GO:0008283| cell proliferation SRC;IL12B GO:0045785| positive regulation of cell adhesion IL12B;SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR;CXCL8 GO:0043066| negative regulation of apoptotic process HCK;IL6;SRC;IL2 GO:0030155| regulation of cell adhesion ABL1;CXCL8 GO:0043065| positive regulation of apoptotic process SRC;IL6;ABL1 GO:0008284| positive regulation of cell proliferation IL6;HCK;IL2;LYN;CDK2 GO:0006935| chemotaxis MAP2K1;CXCL8 GO:0071222| cellular response to lipopolysaccharide ABL1;IL6;SRC;BCR;CXCL8;IL12B GO:0007155| cell adhesion SRC;HCK;ABL1;IL2 GO:0001933| negative regulation of protein phosphorylation IL2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL12B;IL6;IL2 GO:0006954| inflammatory response HCK;IL6;CXCL8;LYN GO:0050728| negative regulation of inflammatory response BCR;IL2 GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;MAP2K1;IL2 GO:0002250| adaptive immune response LYN;IL2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;IL6 GO:0019221| cytokine-mediated signaling pathway HCK;IL6 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;IL6;MAP2K1;CDK2;MAP3K2 GO:0001934| positive regulation of protein phosphorylation ABL1;IL2;LYN 6035:[DB06616 DB00626] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00626|Bacitracin IDE;A2M common genes common pathways GO:0043547| positive regulation of GTPase activity A2M;BCR GO:0051056| regulation of small GTPase mediated signal transduction BCR;A2M GO:0016032| viral reproduction SRC;HCK;IDE;LYN GO:0002576| platelet degranulation A2M;LYN 6036:[DB06616 DB07288] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;FLT1;LYN;CDK2;CAMK2G GO:0030154| cell differentiation FLT1;CAMK2G;HCK GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;FLT1;LYN GO:0030335| positive regulation of cell migration FLT1;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;FLT1;HCK GO:0016310| phosphorylation MAP3K2;FLT1;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0016477| cell migration SRC;FLT1 GO:0043406| positive regulation of MAP kinase activity SRC;FLT1 GO:0046777| protein autophosphorylation ABL1;SRC;BCR;HCK;CAMK2G;LYN;FLT1 GO:0007275| multicellular organismal development CAMK2G;CDK2;FLT1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;FLT1;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway FLT1;SRC GO:0006935| chemotaxis MAP2K1;FLT1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;FLT1;HCK 6037:[DB06616 DB02445] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 6038:[DB06616 DB00583] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC25A29;ABCB1;SLCO1B1;SLC22A8;SLC22A16;SLC22A5;SLC22A4 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0009636| response to toxin SLC22A8;CES1;LYN GO:0014070| response to organic cyclic compound LYN;CPT1A GO:0030154| cell differentiation HCK;CAMK2G;SLC22A16 GO:0006979| response to oxidative stress ABL1;MPO GO:0055114| oxidation-reduction process XDH;CYP3A4;MPO;CYP2C8 GO:0042493| response to drug CPT1A;SRC;ABCB1;LYN GO:0010629| negative regulation of gene expression XDH;MAP2K2;MAP2K1 GO:0007275| multicellular organismal development CAMK2G;SLC22A16;CDK2 GO:0032496| response to lipopolysaccharide BCR;MPO GO:0001933| negative regulation of protein phosphorylation XDH;LYN GO:0006629| lipid metabolic process CRAT;CYP3A4;CPT2;CROT;CPT1A GO:0043066| negative regulation of apoptotic process SRC;MPO;HCK GO:0009612| response to mechanical stimulus SRC;MPO GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0071398| cellular response to fatty acid CPT1A;SRC 6039:[DB06616 DB05944] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05944|Varlitinib ERBB2;EGFR common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;ERBB2;HCK;EGFR;MAP2K1;SRC;MAP2K2;BCR GO:0007275| multicellular organismal development EGFR;CAMK2G;CDK2 GO:0042127| regulation of cell proliferation ABL1;SRC;EGFR GO:0007399| nervous system development ERBB2;CAMK2G GO:0007507| heart development MAP2K1;ERBB2 GO:0071260| cellular response to mechanical stimulus EGFR;MAP3K2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;EGFR GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process EGFR;HCK;SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;EGFR;BCR;SRC GO:2000145| regulation of cell motility ERBB2;ABL1;EGFR GO:0001934| positive regulation of protein phosphorylation LYN;EGFR;ERBB2;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ERBB2 GO:0038083| LYN;EGFR;HCK;SRC;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;EGFR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;EGFR;MAP2K1;CDK2;MAP3K2 GO:0038128| SRC;EGFR;ERBB2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;EGFR;ERBB2 GO:0000165| MAPKKK cascade MAP2K2;EGFR;MAP2K1;ERBB2;CAMK2G GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;EGFR;HCK;ERBB2;ABL1 GO:1903800| MAP2K2;MAP2K1;EGFR GO:0045930| negative regulation of mitotic cell cycle EGFR;ABL1 GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0016310| phosphorylation ABL1;ERBB2;SRC;BCR;MAP2K2;HCK;EGFR;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;ERBB2;HCK;EGFR GO:0030335| positive regulation of cell migration EGFR;LYN GO:0098609| EGFR;SRC GO:0043547| positive regulation of GTPase activity ERBB2;BCR GO:0007165| signal transduction LYN;MAP2K1;EGFR;BCR;SRC;ERBB2 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;ERBB2;EGFR GO:0006979| response to oxidative stress EGFR;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;EGFR;MAP2K1 GO:0045785| positive regulation of cell adhesion ERBB2;SRC GO:0008283| cell proliferation ERBB2;SRC;EGFR GO:0014070| response to organic cyclic compound LYN;EGFR GO:0043406| positive regulation of MAP kinase activity SRC;EGFR;ERBB2 GO:0046777| protein autophosphorylation ERBB2;ABL1;EGFR;HCK;BCR;SRC;LYN;CAMK2G GO:0034614| cellular response to reactive oxygen species EGFR;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;ERBB2 6040:[DB06616 DB05009] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05009|Apadenoson ADORA2A common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;ADORA2A;MAP2K1 GO:0006915| apoptotic process ABL1;ADORA2A GO:0007596| blood coagulation ADORA2A;LYN GO:0007165| signal transduction LYN;ADORA2A;MAP2K1;BCR;SRC GO:0007417| central nervous system development SRC;LYN;ADORA2A GO:0051924| regulation of calcium ion transport CAMK2G;ADORA2A GO:0006954| inflammatory response HCK;LYN;ADORA2A GO:0050728| negative regulation of inflammatory response ADORA2A;BCR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;ADORA2A GO:0006909| phagocytosis ADORA2A;ABL1;HCK GO:0006355| regulation of transcription, DNA-dependent ADORA2A;ABL1 GO:0042493| response to drug ABCB1;SRC;LYN;ADORA2A 6041:[DB06616 DB12518] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12518|Raclopride DRD2 common genes common pathways GO:0007165| signal transduction SRC;DRD2;BCR;MAP2K1;LYN GO:0030900| forebrain development DRD2;SRC GO:0030336| negative regulation of cell migration DRD2;BCR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0009636| response to toxin LYN;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;DRD2;SRC;MAP2K2 GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;DRD2;SRC GO:0048678| response to axon injury LYN;DRD2 GO:0042493| response to drug DRD2;SRC;ABCB1;LYN 6042:[DB06616 DB05281] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0003014| renal system process BCR;BCL2 GO:0030097| hemopoiesis BCL2;LYN GO:0048538| thymus development ABL1;MAP2K1;BCL2 GO:0048536| spleen development ABL1;BCL2 GO:0006979| response to oxidative stress ABL1;BCL2 GO:0071456| cellular response to hypoxia SRC;BCL2 GO:0045930| negative regulation of mitotic cell cycle ABL1;BCL2 GO:0098609| SRC;BCL2 GO:0014911| positive regulation of smooth muscle cell migration BCL2;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCL2 GO:0030336| negative regulation of cell migration BCL2;BCR GO:0009791| post-embryonic development ABL1;BCL2 GO:0050853| B cell receptor signaling pathway LYN;BCL2;ABL1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;BCL2;MAP2K1 GO:0055085| transmembrane transport ABCB1;BCL2 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1;TUBA4A GO:0042100| B cell proliferation ABL1;BCL2 GO:0006915| apoptotic process BCL2;ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis BCL2;ABL1 GO:0008283| cell proliferation BCL2;SRC GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;BCR GO:0009636| response to toxin BCL2;LYN GO:0006470| protein dephosphorylation CAMK2G;BCL2 GO:0042981| regulation of apoptotic process MAP3K2;BCL2;MAP2K1;MAP2K2 GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2;BCL2 GO:0008284| positive regulation of cell proliferation BCL2;CDK2;LYN;HCK GO:0051726| regulation of cell cycle BCL2;ABL1;SRC;BCR GO:0042542| response to hydrogen peroxide BCL2;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;BCL2 GO:0002576| platelet degranulation LYN;TUBA4A GO:0043066| negative regulation of apoptotic process BCL2;HCK;SRC GO:0051924| regulation of calcium ion transport CAMK2G;BCL2 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2 GO:0001782| B cell homeostasis LYN;BCL2 GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;TUBA4A GO:2000811| negative regulation of anoikis SRC;BCL2 GO:0051902| negative regulation of mitochondrial depolarization SRC;BCL2 GO:0042493| response to drug ABCB1;SRC;LYN;BCL2 GO:0010506| regulation of autophagy ABL1;BCL2 6043:[DB06616 DB11311] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11311|Prothrombin FGA;FGB;F13A1;CPB2;F10 common genes common pathways GO:0002250| adaptive immune response FGB;FGA;LYN GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0042493| response to drug ABCB1;SRC;CPB2;LYN GO:0045087| innate immune response LYN;ABL1;SRC;FGB;FGA;HCK GO:0002576| platelet degranulation F13A1;FGB;FGA;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;FGB;MAP2K2;FGA;MAP2K1 GO:0007596| blood coagulation CPB2;FGA;FGB;F13A1;LYN;F10 GO:2000352| negative regulation of endothelial cell apoptosis FGA;FGB;ABL1 GO:0007165| signal transduction LYN;FGA;MAP2K1;FGB;SRC;BCR GO:1900026| ABL1;FGA;FGB GO:0002376| immune system process LYN;SRC;FGB;FGA;HCK GO:0030168| platelet activation LYN;FGA;FGB;SRC GO:0030335| positive regulation of cell migration LYN;F10 6044:[DB06616 DB08391] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;PDE10A 6045:[DB06616 DB07775] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways GO:0006810| transport ABCB1;TTR 6046:[DB06616 DB06439] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06439|Tyloxapol LPL common genes common pathways GO:0042493| response to drug SRC;ABCB1;LPL;LYN GO:0006629| lipid metabolic process LPL;CYP3A4 6047:[DB06616 DB00158] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC3 GO:0006810| transport ABCB1;ABCG2;ABCC3 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0070555| response to interleukin-1 SRC;MTHFR GO:0043200| response to amino acid stimulus MTHFR;LYN GO:0014070| response to organic cyclic compound ABCC4;LYN GO:0032868| response to insulin stimulus LYN;GGH GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC3 GO:0055085| transmembrane transport ABCC3;SLC22A6;ABCG2;ABCC4;ABCC11;SLC46A1;ABCB1 GO:0010033| response to organic substance ABCC4;CDK2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0048678| response to axon injury LYN;FOLR1 GO:0002576| platelet degranulation ALB;ABCC4;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;FOLR2;HCK GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0042493| response to drug GGH;MTHFR;LYN;CYP2E1;ABCC4;ABCB1;SRC;ABCG2 GO:0055114| oxidation-reduction process MTHFR;CYP3A4;CYP2E1;ABCC4;CYP2C8 GO:0006954| inflammatory response FOLR2;LYN;HCK 6048:[DB06616 DB12702] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12702|Velusetrag HTR4 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;HTR4 6049:[DB06616 DB03554] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03554|5-Iodouracil DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DPYD;CYP3A4 6050:[DB06616 DB08473] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08473|5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole CSNK2A1 common genes common pathways GO:0007165| signal transduction CSNK2A1;LYN;MAP2K1;BCR;SRC GO:0006468| protein phosphorylation MAP3K2;CSNK2A1;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2;CSNK2A1 GO:0007049| cell cycle SRC;CDK2;CSNK2A1 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CSNK2A1;MAP2K1 GO:0008284| positive regulation of cell proliferation HCK;CSNK2A1;CDK2;LYN GO:1901796| CDK2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:0016236| macroautophagy SRC;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 6051:[DB06616 DB04356] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 6052:[DB06616 DB08056] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K1;LCK;HCK;MAP2K2;BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC;LCK GO:0045087| innate immune response SRC;LCK;HCK;ABL1;LYN GO:0050900| leukocyte migration SRC;LCK;LYN GO:0042493| response to drug LCK;SRC;ABCB1;LYN GO:0038083| SRC;HCK;LCK;ABL1;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;LCK GO:0016032| viral reproduction SRC;HCK;LCK;LYN GO:0030168| platelet activation LCK;SRC;LYN GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;LCK;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;LCK;HCK GO:0031295| T cell costimulation LYN;SRC;LCK GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;LCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0030097| hemopoiesis LCK;LYN GO:0016477| cell migration LCK;SRC GO:0006470| protein dephosphorylation CAMK2G;LCK GO:0050690| regulation of defense response to virus by virus HCK;LCK GO:0050853| B cell receptor signaling pathway LYN;LCK;ABL1 6053:[DB06616 DB07124] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07124|(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE PRKACA common genes common pathways GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;PRKACA GO:0018105| peptidyl-serine phosphorylation PRKACA;CDK2;CAMK2G;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PRKACA;SRC GO:0043393| regulation of protein binding SRC;PRKACA GO:0000086| G2/M transition of mitotic cell cycle CDK2;PRKACA;ABCB1 GO:0007596| blood coagulation LYN;PRKACA GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;PRKACA;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;PRKACA;LYN;CDK2;CAMK2G;MAP3K2 GO:0034605| cellular response to heat LYN;PRKACA 6054:[DB06616 DB00376] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007165| signal transduction CHRM1;LYN;CHRM2;CHRM5;CHRM3;BCR;SRC;MAP2K1;CHRM4 GO:0008283| cell proliferation CHRM1;CHRM5;CHRM3;SRC;CHRM4 GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0008284| positive regulation of cell proliferation HCK;CHRM1;LYN;CDK2 GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM3;CHRM2;CAMK2G;CHRM1 6055:[DB06616 DB00901] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00901|Bitolterol ADRB2 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 GO:0007165| signal transduction LYN;ADRB2;MAP2K1;BCR;SRC GO:0045453| bone resorption ADRB2;SRC 6056:[DB06616 DB00692] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug LYN;ADRA1A;SRC;ABCB1 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0007275| multicellular organismal development CDK2;CAMK2G;ADRA1D;ADRA1B GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;ADRA1D;CDK2;LYN GO:0035556| intracellular signal transduction ADRA1B;BCR;ADRA1A;SRC;CAMK2G;LYN GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0008283| cell proliferation ADRA1B;SRC;ADRA1D GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;ADRA1A;MAP2K2;ABL1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;LYN GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1;ADRA1A;ADRA1D GO:0030168| platelet activation LYN;SRC;ADRA2A GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction LYN;ADRA1D;ADRA2A;ADRA1B;SRC;ADRA1A;BCR;MAP2K1 6057:[DB06616 DB07167] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;CSF1R GO:0008283| cell proliferation SRC;CSF1R GO:0007411| axon guidance SRC;CSF1R GO:0008285| negative regulation of cell proliferation MAP2K1;CSF1R;LYN GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;CSF1R;SRC;MAP2K2 GO:0046777| protein autophosphorylation SRC;BCR;HCK;CSF1R;ABL1;CAMK2G;LYN GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;CSF1R;MAP2K1;ABL1 GO:0016310| phosphorylation MAP2K1;CSF1R;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway CSF1R;HCK;LYN GO:0030335| positive regulation of cell migration CSF1R;LYN GO:0007165| signal transduction SRC;BCR;CSF1R;MAP2K1;LYN GO:0030097| hemopoiesis LYN;CSF1R GO:0002376| immune system process HCK;CSF1R;SRC;LYN GO:0001934| positive regulation of protein phosphorylation LYN;CSF1R;ABL1 GO:0019221| cytokine-mediated signaling pathway CSF1R;HCK GO:0006954| inflammatory response HCK;CSF1R;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein CSF1R;LYN GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K2;BCR;SRC;MAP2K1;CSF1R;HCK;ABL1 GO:0007275| multicellular organismal development CAMK2G;CDK2;CSF1R GO:0008360| regulation of cell shape HCK;CSF1R GO:0045087| innate immune response LYN;ABL1;SRC;CSF1R;HCK GO:0045124| regulation of bone resorption CSF1R;SRC GO:0008284| positive regulation of cell proliferation HCK;CSF1R;LYN;CDK2 GO:0043066| negative regulation of apoptotic process HCK;CSF1R;SRC GO:2000249| regulation of actin cytoskeleton reorganization CSF1R;ABL1 6058:[DB06616 DB01303] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;ADORA2A GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug SRC;ABCB1;HDAC2;PDE3A;CYP1A2;ADORA2A;LYN GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;HDAC2;ABL1 GO:0006909| phagocytosis ADORA1;ADORA2A;ABL1;HCK GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;HDAC2;MAP3K2;CDK2 GO:0051924| regulation of calcium ion transport ADORA2A;CAMK2G GO:0050728| negative regulation of inflammatory response BCR;ADORA2A;ADORA1 GO:0006954| inflammatory response HCK;ADORA1;ADORA2A;LYN GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;HDAC2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR;HDAC2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;HDAC2 GO:0007399| nervous system development ADORA1;CAMK2G GO:0006629| lipid metabolic process PDE3A;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:1901796| HDAC2;CDK2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HDAC2;HCK GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0071300| cellular response to retinoic acid LYN;HDAC2 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;HDAC2;PDE3A GO:0043066| negative regulation of apoptotic process SRC;HCK;HDAC2;PDE3A;ADORA1 GO:0055085| transmembrane transport SLC22A7;ABCB1 GO:0006915| apoptotic process ABL1;ADORA2A GO:0007596| blood coagulation HDAC2;ADORA2A;LYN GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0070301| cellular response to hydrogen peroxide ABL1;HDAC2 GO:0008285| negative regulation of cell proliferation MAP2K1;ADORA2A;LYN;ADORA1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent HDAC2;SRC GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0000186| activation of MAPKK activity ADORA1;MAP3K2 GO:0007417| central nervous system development LYN;ADORA2A;SRC GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0034605| cellular response to heat HDAC2;LYN GO:0007165| signal transduction SRC;BCR;MAP2K1;PDE3A;PDE4A;ADORA1;ADORA2A;LYN GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:1903351| HDAC2;ABL1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 6059:[DB06616 DB08341] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0002250| adaptive immune response PTK2B;LYN GO:0071498| cellular response to fluid shear stress PTK2B;SRC GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;PTK2B;CAMK2G GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation PTK2B;ABL1;SRC;LYN GO:0010976| positive regulation of neuron projection development LYN;PTK2B GO:0007173| epidermal growth factor receptor signaling pathway SRC;PTK2B;ABL1 GO:0042493| response to drug PTK2B;SRC;ABCB1;LYN GO:0038083| ABL1;PTK2B;HCK;SRC;LYN GO:0008360| regulation of cell shape PTK2B;HCK GO:0045087| innate immune response PTK2B;ABL1;SRC;HCK;LYN GO:0007155| cell adhesion ABL1;PTK2B;HCK;SRC GO:0043066| negative regulation of apoptotic process PTK2B;SRC;HCK GO:0009612| response to mechanical stimulus PTK2B;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway PTK2B;SRC GO:0030155| regulation of cell adhesion ABL1;PTK2B GO:0071300| cellular response to retinoic acid LYN;PTK2B GO:2000249| regulation of actin cytoskeleton reorganization PTK2B;ABL1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;PTK2B GO:0042542| response to hydrogen peroxide SRC;PTK2B GO:0018108| peptidyl-tyrosine phosphorylation LYN;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;PTK2B GO:2000573| positive regulation of DNA biosynthetic process SRC;PTK2B GO:0030838| positive regulation of actin filament polymerization HCK;PTK2B GO:0042127| regulation of cell proliferation SRC;ABL1;PTK2B GO:0008285| negative regulation of cell proliferation PTK2B;MAP2K1;LYN GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;PTK2B;HCK;SRC;BCR GO:0006915| apoptotic process PTK2B;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;PTK2B GO:0031175| neuron projection development PTK2B;LYN GO:0009725| response to hormone stimulus PTK2B;LYN GO:0007165| signal transduction LYN;PTK2B;SRC;BCR;MAP2K1 GO:0007172| signal complex assembly PTK2B;SRC GO:0045453| bone resorption SRC;PTK2B GO:0002376| immune system process PTK2B;HCK;SRC;LYN GO:0043149| stress fiber assembly SRC;PTK2B GO:0007229| integrin-mediated signaling pathway PTK2B;ABL1;HCK;SRC GO:0007204| elevation of cytosolic calcium ion concentration PTK2B;ABL1 GO:0030154| cell differentiation PTK2B;HCK;CAMK2G GO:0006468| protein phosphorylation PTK2B;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;MAP3K2 GO:0030335| positive regulation of cell migration LYN;PTK2B GO:0051279| regulation of release of sequestered calcium ion into cytosol LYN;PTK2B GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC;PTK2B GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;PTK2B;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0010595| positive regulation of endothelial cell migration ABL1;PTK2B 6060:[DB06616 DB13627] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug LYN;CYP1A2;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 6061:[DB06616 DB05036] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2;SCYL1 GO:0071456| cellular response to hypoxia TERT;SRC GO:0007165| signal transduction LYN;PTGES3;MAP2K1;BCR;SRC GO:1900034| PTGES3;CAMK2G GO:2000773| negative regulation of cellular senescence TERT;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;TERT GO:0018108| peptidyl-tyrosine phosphorylation SCYL1;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0006629| lipid metabolic process CYP3A4;PTGES3 GO:0006805| xenobiotic metabolic process PTGES3;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process HCK;SRC;TERT GO:0042327| positive regulation of phosphorylation PTGES3;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TERT GO:0006355| regulation of transcription, DNA-dependent SCYL1;ABL1 6062:[DB06616 DB07969] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;SRC GO:0000165| MAPKKK cascade MET;CAMK2G;MAP2K1;MAP2K2 GO:0018108| peptidyl-tyrosine phosphorylation LYN;MET;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0035635| entry of bacterium into host cell MET;SRC GO:0008283| cell proliferation MET;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;MET;LYN GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2;MET GO:0006468| protein phosphorylation MET;MAP3K2;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0007165| signal transduction MET;LYN;SRC;BCR;MAP2K1 6063:[DB06616 DB03902] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03902|Oxalic Acid SRC;SLCO2B1;SLC22A8 common genes SRC common pathways GO:0051895| negative regulation of focal adhesion assembly SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;SRC;BCR GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0009636| response to toxin LYN;SLC22A8 GO:0016477| cell migration SRC GO:0055085| transmembrane transport SLC22A8;ABCB1;SLCO2B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0002376| immune system process HCK;SRC;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0045453| bone resorption SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1 GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0031295| T cell costimulation LYN;SRC GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0071456| cellular response to hypoxia SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0048477| oogenesis SRC GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0016032| viral reproduction SRC;HCK;LYN GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| LYN;HCK;SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0038083| LYN;HCK;SRC;ABL1 GO:0042493| response to drug ABCB1;SRC;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0031667| response to nutrient levels SRC GO:0050900| leukocyte migration SRC;LYN GO:0034332| adherens junction organization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion ABL1;HCK;SRC GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0045056| transcytosis SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0043393| regulation of protein binding SRC GO:0086098| SRC GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;LYN 6064:[DB06616 DB04249] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04249|Zinc Substituted Heme C CYCS common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYCS GO:0034599| cellular response to oxidative stress ABL1;CYCS GO:0006915| apoptotic process ABL1;CYCS GO:0006470| protein dephosphorylation CYCS;CAMK2G 6065:[DB06616 DB01890] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways GO:0030335| positive regulation of cell migration LYN;IGF1 GO:0007165| signal transduction MAP2K1;SRC;BCR;IGF1;LYN GO:0008283| cell proliferation SRC;IGF1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway IGF1;SRC GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;IGF1;MAP3K2 GO:0032868| response to insulin stimulus PPARA;LYN GO:0006928| cellular component movement IGF1;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;IGF1 GO:0014911| positive regulation of smooth muscle cell migration IGF1;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IGF1;LYN GO:0007265| Ras protein signal transduction CDK2;IGF1 GO:0043066| negative regulation of apoptotic process IGF1;HCK;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;IGF1 GO:0002576| platelet degranulation IGF1;LYN GO:0006629| lipid metabolic process CYP3A4;PPARA GO:0032148| activation of protein kinase B activity SRC;IGF1 GO:0007507| heart development MAP2K1;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARA GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;PPARA;MAP3K2;IGF1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARA GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;IGF1 GO:0006260| DNA replication CDK2;IGF1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;IGF1;LYN 6066:[DB06616 DB08237] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08237|2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) POLK common genes common pathways GO:0006260| DNA replication POLK;CDK2 GO:0006281| DNA repair POLK;ABL1;CDK2 GO:0006974| response to DNA damage stimulus LYN;CDK2;POLK;ABL1 6067:[DB06616 DB14014] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14014|SR-9011 NR1D2;NR1D1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1D1;CDK2;NR1D2 GO:0050727| regulation of inflammatory response LYN;HCK;NR1D2 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;NR1D1 GO:0045893| positive regulation of transcription, DNA-dependent NR1D2;MAP2K1;SRC;MAP2K2;MAP3K2;NR1D1;CDK2 GO:0006355| regulation of transcription, DNA-dependent NR1D1;NR1D2;ABL1 GO:0030154| cell differentiation NR1D1;CAMK2G;HCK GO:0034144| negative regulation of toll-like receptor 4 signaling pathway LYN;NR1D1 GO:0045892| negative regulation of transcription, DNA-dependent NR1D1;SRC;NR1D2 6068:[DB06616 DB00535] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;MPO GO:0043066| negative regulation of apoptotic process HCK;MPO;SRC GO:0009612| response to mechanical stimulus MPO;SRC GO:0032496| response to lipopolysaccharide BCR;MPO GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC15A1;SLC22A5;SLC15A2;SLC22A8 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0009636| response to toxin SLC22A8;LYN GO:0006979| response to oxidative stress MPO;ABL1 GO:0006810| transport ABCB1;SLC15A2;SLC15A1 6069:[DB06616 DB05070] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05070|ADX10059 GRM5 common genes common pathways GO:0007165| signal transduction LYN;GRM5;MAP2K1;SRC;BCR GO:0001932| regulation of protein phosphorylation LYN;GRM5;MAP2K1 6070:[DB06616 DB05481] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways GO:0007596| blood coagulation SERPINA1;LYN GO:0002576| platelet degranulation SERPINA1;LYN 6071:[DB06616 DB14520] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:1900026| CALR;ABL1 GO:0010595| positive regulation of endothelial cell migration ITGB3;ABL1;CALR GO:0007229| integrin-mediated signaling pathway ITGB3;HCK;SRC;ABL1 GO:0030168| platelet activation LYN;SRC;ITGB3 GO:0010628| positive regulation of gene expression SRC;MAP2K1;CALR GO:0010033| response to organic substance CALR;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;CALR GO:0050766| positive regulation of phagocytosis BCR;CALR GO:0007596| blood coagulation LYN;ITGB3 GO:0002576| platelet degranulation TF;LYN;ITGB3 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CALR GO:0006897| endocytosis TFRC;ABL1 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;ITGB3 GO:0007155| cell adhesion SRC;ITGB3;HCK;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CALR GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;CALR;MAP3K2 GO:0045124| regulation of bone resorption SRC;ITGB3 GO:0042127| regulation of cell proliferation TFRC;ABL1;SRC GO:0016032| viral reproduction TFRC;LYN;ITGB3;HCK;SRC GO:0090398| cellular senescence CALR;MAP2K1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;ITGB3;SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC;ITGB3 GO:0042493| response to drug LYN;CALR;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CALR GO:0050900| leukocyte migration LYN;SRC;ITGB3 GO:0001934| positive regulation of protein phosphorylation ITGB3;ABL1;LYN 6072:[DB06616 DB04991] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04991|XL784 ADAM10 common genes common pathways GO:0030335| positive regulation of cell migration LYN;ADAM10 GO:0007229| integrin-mediated signaling pathway ABL1;ADAM10;HCK;SRC GO:0006468| protein phosphorylation ADAM10;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0008284| positive regulation of cell proliferation HCK;ADAM10;LYN;CDK2 6073:[DB06616 DB00723] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00723|Methoxamine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug SRC;ADRA1A;ABCB1;LYN GO:0007275| multicellular organismal development ADRA1B;CDK2;CAMK2G;ADRA1D GO:0008284| positive regulation of cell proliferation ADRA1D;CDK2;LYN;HCK GO:0035556| intracellular signal transduction LYN;CAMK2G;ADRA1B;BCR;SRC;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;ADRA1A;SRC;ABL1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0008283| cell proliferation ADRA1D;ADRA1B;SRC GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1B;ABL1;ADRA1D GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction ADRA1B;MAP2K1;ADRA1A;SRC;BCR;LYN;ADRA1D 6074:[DB06616 DB00025] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0006897| endocytosis LRP1;ASGR2;ABL1 GO:0043066| negative regulation of apoptotic process SRC;PROC;HCK;HSPA5 GO:0002576| platelet degranulation VWF;LYN GO:0008284| positive regulation of cell proliferation HCK;F2;LYN;CDK2;CALR GO:0006629| lipid metabolic process CYP3A4;LRP1 GO:0007155| cell adhesion SRC;HCK;ABL1;VWF GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CALR GO:0008360| regulation of cell shape F2;HCK GO:0042981| regulation of apoptotic process CALR;MAP3K2;MAP2K1;MAP2K2 GO:0045056| transcytosis SRC;LRP1 GO:0007275| multicellular organismal development F2;CAMK2G;CDK2;LRP1 GO:0090398| cellular senescence CALR;MAP2K1 GO:0010976| positive regulation of neuron projection development HSPA5;LYN GO:0050728| negative regulation of inflammatory response PROC;BCR GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0006909| phagocytosis ABL1;HCK;LRP1 GO:0042493| response to drug LYN;CALR;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CALR GO:0055114| oxidation-reduction process CYP2C8;PHYH;CYP3A4 GO:0001934| positive regulation of protein phosphorylation F2;ABL1;LYN GO:0050900| leukocyte migration LYN;SRC;PROC;F2 GO:1900026| CALR;ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1;LRP1 GO:1900182| F2;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;F2 GO:0051222| positive regulation of protein transport LRP1;SRC GO:0030335| positive regulation of cell migration LYN;F10;HSPA5 GO:0010595| positive regulation of endothelial cell migration ABL1;CALR GO:0030168| platelet activation F2;SRC;LYN;VWF GO:0010628| positive regulation of gene expression SRC;MAP2K1;CALR GO:0010033| response to organic substance CALR;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent CALR;SRC GO:0050766| positive regulation of phagocytosis CALR;BCR GO:0008283| cell proliferation LRP1;SRC GO:0030182| neuron differentiation HSPA5;MAP2K1;ABL1 GO:0007596| blood coagulation F2;LMAN1;PROC;F9;VWF;F10;LYN 6075:[DB06616 DB07086] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07086|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL NCOA2;ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction ESR1;LYN;SRC;BCR;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;ESR1;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA2;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0060065| uterus development ESR1;SRC GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;ESR1 6076:[DB06616 DB01365] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;LYN GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0008283| cell proliferation ADRA1B;SRC;ADRA1D GO:0000187| activation of MAPK activity MAP3K2;ADRA2B;MAP2K1;MAP2K2 GO:0006915| apoptotic process ABL1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;ADRA1A;MAP2K2;MAP2K1;ABL1 GO:0045453| bone resorption SRC;ADRB2 GO:0007165| signal transduction ADRA2C;ADRB2;ADRA2B;LYN;ADRA1D;ADRA1B;ADRA2A;ADRB3;BCR;ADRA1A;SRC;ADRB1;MAP2K1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0030168| platelet activation ADRA2C;ADRA2B;LYN;ADRA2A;SRC GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ABL1;ADRA1B;ADRA1D GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0042493| response to drug LYN;SRC;ADRA1A;ABCB1 GO:0035556| intracellular signal transduction LYN;CAMK2G;ADRA1B;BCR;ADRA1A;SRC GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;ADRA1D;LYN;CDK2 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0007275| multicellular organismal development ADRA1B;CAMK2G;CDK2;ADRA1D GO:0007265| Ras protein signal transduction CDK2;ADRA2A 6077:[DB06616 DB01157] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01157|Trimetrexate DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 6078:[DB06616 DB07853] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07853|[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE SLK;CAMK2D;STK26 common genes common pathways GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;CAMK2D;HCK GO:1900034| CAMK2G;CAMK2D GO:0016310| phosphorylation MAP3K2;SLK;CAMK2G;CAMK2D;CDK2;LYN;MAP2K2;BCR;STK26;SRC;MAP2K1;HCK;ABL1 GO:0030154| cell differentiation HCK;CAMK2G;CAMK2D GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;STK26;HCK;MAP2K1;ABL1;MAP3K2;SLK;CAMK2G;CAMK2D;LYN;CDK2 GO:0046777| protein autophosphorylation ABL1;SRC;STK26;BCR;HCK;CAMK2G;LYN;CAMK2D;SLK GO:0030336| negative regulation of cell migration BCR;STK26 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2D;CAMK2G GO:0006915| apoptotic process SLK;ABL1;STK26 GO:0042542| response to hydrogen peroxide STK26;SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CAMK2D;CDK2;SRC GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;STK26;MAP3K2;SLK GO:0007399| nervous system development CAMK2D;CAMK2G GO:1901897| CAMK2D;CAMK2G GO:0051259| protein oligomerization CAMK2G;CAMK2D GO:0000165| MAPKKK cascade CAMK2D;CAMK2G;MAP2K1;STK26;MAP2K2 GO:0007346| regulation of mitotic cell cycle MAP2K1;STK26;MAP2K2;SLK;MAP3K2 GO:0023014| signal transduction via phosphorylation event LYN;SLK 6079:[DB06616 DB05085] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05085|TM30339 NPY4R common genes common pathways GO:0007165| signal transduction LYN;NPY4R;MAP2K1;SRC;BCR 6080:[DB06616 DB09211] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways GO:0007165| signal transduction LYN;PTGER3;PTGER1;PTGER4;MAP2K1;PTGER2;SRC;BCR GO:0050715| positive regulation of cytokine secretion SRC;PTGER4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGER4 GO:0009612| response to mechanical stimulus SRC;PTGER4 GO:0042127| regulation of cell proliferation PTGER2;SRC;ABL1 GO:0032496| response to lipopolysaccharide PTGER2;BCR;PTGER1;PTGER4 GO:0070371| ERK1 and ERK2 cascade PTGER4;MAP2K2;MAP2K1 GO:0050728| negative regulation of inflammatory response BCR;PTGER4 6081:[DB06616 DB00219] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00219|Oxyphenonium CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CHRM1 GO:0007399| nervous system development CHRM1;CAMK2G GO:0008283| cell proliferation CHRM1;SRC GO:0006464| protein modification process CHRM1;ABL1 GO:0007165| signal transduction LYN;CHRM1;MAP2K1;BCR;SRC 6082:[DB06616 DB13928] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;GLP1R;LYN GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;ABL1 GO:0031295| T cell costimulation SRC;LYN;DPP4 GO:0055085| transmembrane transport ABCB1;SLCO1B1;SLCO1B3 GO:0006629| lipid metabolic process LPL;CYP3A4 GO:0007155| cell adhesion DPP4;ABL1;SRC;HCK GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0008284| positive regulation of cell proliferation HCK;DPP4;CDK2;LYN GO:0002576| platelet degranulation LYN;ALB GO:0043542| endothelial cell migration DPP4;ABL1 GO:0042493| response to drug LYN;LPL;SRC;ABCB1 6083:[DB06616 DB06771] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug LYN;CYP1A2;SRC;ABCB1 6084:[DB06616 DB06800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0007165| signal transduction OPRM1;LYN;MAP2K1;SRC;BCR;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K1;SRC;MAP2K2;ABL1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;OPRM1 GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;SRC;BCR 6085:[DB06616 DB03347] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03347|Triethyl Phosphate TP53 common genes common pathways GO:0007265| Ras protein signal transduction CDK2;TP53 GO:0007275| multicellular organismal development CDK2;CAMK2G;TP53 GO:0043065| positive regulation of apoptotic process TP53;SRC;ABL1 GO:1901796| TP53;CDK2 GO:0031571| mitotic cell cycle G1/S transition DNA damage checkpoint TP53;CDK2 GO:0043066| negative regulation of apoptotic process SRC;HCK;TP53 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP53;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;TP53 GO:0051974| negative regulation of telomerase activity TP53;SRC GO:0006974| response to DNA damage stimulus TP53;CDK2;LYN;ABL1 GO:0042493| response to drug SRC;ABCB1;TP53;LYN GO:0006355| regulation of transcription, DNA-dependent TP53;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;TP53;CDK2 GO:0006914| autophagy ABL1;TP53 GO:0016032| viral reproduction LYN;TP53;HCK;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;TP53 GO:0034605| cellular response to heat LYN;TP53 GO:0030154| cell differentiation HCK;CAMK2G;TP53 GO:0071456| cellular response to hypoxia TP53;SRC GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TP53;CDK2 GO:0006979| response to oxidative stress ABL1;TP53 GO:0007050| cell cycle arrest MAP2K1;ABL1;TP53 GO:0008283| cell proliferation SRC;TP53 GO:0043200| response to amino acid stimulus LYN;TP53 GO:0014070| response to organic cyclic compound TP53;LYN GO:0006915| apoptotic process TP53;ABL1 GO:0010628| positive regulation of gene expression TP53;SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC;TP53 GO:0007049| cell cycle SRC;CDK2;TP53 GO:0008285| negative regulation of cell proliferation LYN;TP53;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent TP53;SRC 6086:[DB06616 DB05146] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05146|XL820 KDR;KIT;PDGFRA;PDGFRB common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade PDGFRB;ABL1;KDR;MAP2K1;PDGFRA;MAP2K2;SRC GO:0000187| activation of MAPK activity MAP3K2;KIT;MAP2K1;MAP2K2 GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0016477| cell migration PDGFRB;SRC GO:0009636| response to toxin LYN;PDGFRB GO:0014070| response to organic cyclic compound PDGFRB;LYN GO:0043406| positive regulation of MAP kinase activity KIT;SRC;PDGFRB GO:0014911| positive regulation of smooth muscle cell migration SRC;PDGFRB GO:0046777| protein autophosphorylation ABL1;HCK;PDGFRA;KDR;KIT;SRC;BCR;LYN;PDGFRB;CAMK2G GO:0010628| positive regulation of gene expression MAP2K1;KIT;SRC GO:0034614| cellular response to reactive oxygen species SRC;PDGFRA GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;PDGFRA;HCK;KDR;KIT;MAP2K1;PDGFRB;CAMK2G;CDK2;LYN;MAP3K2 GO:0030154| cell differentiation KDR;HCK;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;PDGFRA GO:0035791| platelet-derived growth factor receptor-beta signaling pathway PDGFRB;ABL1 GO:0036120| SRC;PDGFRB GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation LYN;CDK2;CAMK2G;PDGFRB;MAP3K2;ABL1;MAP2K1;KIT;KDR;HCK;PDGFRA;MAP2K2;BCR;SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;PDGFRA;KIT;PDGFRB;LYN GO:0030335| positive regulation of cell migration PDGFRA;KIT;KDR;LYN;PDGFRB GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway PDGFRB;LYN;KIT;KDR;HCK;PDGFRA GO:0007165| signal transduction SRC;BCR;MAP2K1;KIT;PDGFRB;LYN GO:0030097| hemopoiesis KIT;LYN GO:0032956| regulation of actin cytoskeleton organization ABL1;PDGFRB GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;KDR GO:0038083| LYN;HCK;KDR;SRC;ABL1 GO:0010629| negative regulation of gene expression MAP2K2;KDR;MAP2K1 GO:0019221| cytokine-mediated signaling pathway KIT;HCK GO:0000165| MAPKKK cascade CAMK2G;PDGFRB;MAP2K2;KIT;MAP2K1;PDGFRA GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRB;PDGFRA;KIT;SRC GO:0030218| erythrocyte differentiation LYN;KIT GO:0070371| ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2 GO:0006954| inflammatory response LYN;HCK;KIT GO:0016032| viral reproduction SRC;HCK;PDGFRA;KDR;LYN GO:2000573| positive regulation of DNA biosynthetic process PDGFRB;SRC GO:0007275| multicellular organismal development CDK2;CAMK2G;PDGFRB;KDR;PDGFRA GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;KIT;KDR;HCK;PDGFRA;PDGFRB;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein KIT;LYN GO:0042127| regulation of cell proliferation ABL1;KIT;SRC GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0048008| platelet-derived growth factor receptor signaling pathway PDGFRB;PDGFRA;SRC;BCR;ABL1 GO:0008360| regulation of cell shape HCK;KIT;KDR GO:0043065| positive regulation of apoptotic process SRC;ABL1;PDGFRB GO:0042542| response to hydrogen peroxide SRC;PDGFRB GO:0008284| positive regulation of cell proliferation HCK;PDGFRA;KDR;KIT;PDGFRB;LYN;CDK2 GO:0006935| chemotaxis PDGFRB;PDGFRA;MAP2K1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1;PDGFRA GO:0035556| intracellular signal transduction LYN;PDGFRB;CAMK2G;KIT;SRC;BCR GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process PDGFRB;SRC;KDR;HCK 6087:[DB06616 DB00354] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways GO:0007399| nervous system development CAMK2G;CHRM1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0007165| signal transduction BCR;SRC;MAP2K1;HRH1;CHRM1;LYN GO:0006464| protein modification process CHRM1;ABL1 GO:0008283| cell proliferation CHRM1;SRC 6088:[DB06616 DB04831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04831|Tienilic acid CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 6089:[DB06616 DB05399] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05399|Succinobucol VCAM1 common genes common pathways GO:0060333| interferon-gamma-mediated signaling pathway VCAM1;CAMK2G;HCK GO:0098609| VCAM1;SRC GO:0016032| viral reproduction VCAM1;LYN;SRC;HCK GO:0055114| oxidation-reduction process CYP3A4;VCAM1;CYP2C8 GO:0007155| cell adhesion HCK;SRC;ABL1;VCAM1 GO:0032496| response to lipopolysaccharide BCR;VCAM1 6090:[DB06616 DB02698] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 6091:[DB06616 DB08342] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08342|S-PALMITOYL-L-CYSTEINE TRAPPC6A;TRAPPC3;TRAPPC6B;TRAPPC5;TRAPPC4;TRAPPC1 common genes common pathways GO:0065009| regulation of molecular function TRAPPC6B;CAMK2G;TRAPPC3;TRAPPC1;TRAPPC4;TRAPPC6A;TRAPPC5 6092:[DB06616 DB02918] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02918|Zardaverine PDE4D common genes common pathways GO:0007165| signal transduction LYN;PDE4D;MAP2K1;SRC;BCR GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PDE4D GO:0050900| leukocyte migration LYN;PDE4D;SRC 6093:[DB06616 DB01752] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways GO:0031175| neuron projection development PRMT1;LYN GO:0006464| protein modification process ABL1;PCMT1;GNMT GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;PRMT1 GO:0007420| brain development HNMT;BCR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;SETD7;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent PRMT1;ABL1;PRMT3;SETD7 GO:0008284| positive regulation of cell proliferation CDK2;LYN;PRMT1;HCK GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;SETD7 6094:[DB06616 DB08610] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08610|N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE PDK2 common genes common pathways GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;PDK2;CDK2;LYN;CAMK2G GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;PDK2;CDK2;LYN GO:0034614| cellular response to reactive oxygen species PDK2;SRC 6095:[DB06616 DB04379] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04379|N-Methyl-N-(Methylbenzyl)Formamide REN;CYP2E1 common genes common pathways GO:0042493| response to drug LYN;REN;CYP2E1;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide BCR;REN GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0010033| response to organic substance REN;CDK2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 6096:[DB06616 DB01970] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;PDE3B;BCR;SRC GO:0032869| cellular response to insulin stimulus PDE3B;SRC 6097:[DB06616 DB07162] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;JAK2 GO:0046777| protein autophosphorylation CAMK2G;LYN;JAK2;ABL1;BCR;SRC;HCK GO:0006928| cellular component movement JAK2;MAP2K1 GO:0006915| apoptotic process JAK2;ABL1 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;JAK2 GO:0007596| blood coagulation LYN;JAK2 GO:0016477| cell migration JAK2;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;JAK2 GO:0060333| interferon-gamma-mediated signaling pathway JAK2;CAMK2G;HCK GO:0022408| negative regulation of cell-cell adhesion ABL1;JAK2 GO:0002376| immune system process SRC;HCK;JAK2;LYN GO:0006979| response to oxidative stress JAK2;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration JAK2;ABL1 GO:0006468| protein phosphorylation MAP3K2;JAK2;CDK2;LYN;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0030154| cell differentiation JAK2;CAMK2G;HCK GO:0000186| activation of MAPKK activity JAK2;MAP3K2 GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;JAK2;MAP3K2;CAMK2G;CDK2;LYN GO:0030335| positive regulation of cell migration JAK2;LYN GO:0019221| cytokine-mediated signaling pathway JAK2;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;JAK2;ABL1;SRC GO:0030218| erythrocyte differentiation JAK2;LYN GO:0002250| adaptive immune response LYN;JAK2 GO:0000165| MAPKKK cascade CAMK2G;JAK2;MAP2K1;MAP2K2 GO:0038083| LYN;JAK2;ABL1;SRC;HCK GO:0042981| regulation of apoptotic process MAP3K2;JAK2;MAP2K1;MAP2K2 GO:0045087| innate immune response JAK2;LYN;HCK;SRC;ABL1 GO:0045597| positive regulation of cell differentiation JAK2;MAP2K1 GO:0008284| positive regulation of cell proliferation JAK2;CDK2;LYN;HCK GO:0050727| regulation of inflammatory response JAK2;LYN;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;JAK2 GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G;JAK2 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;JAK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;JAK2 GO:0007498| mesoderm development JAK2;HCK GO:0032496| response to lipopolysaccharide JAK2;BCR GO:0042127| regulation of cell proliferation ABL1;SRC;JAK2 GO:0048008| platelet-derived growth factor receptor signaling pathway JAK2;SRC;BCR;ABL1 6098:[DB06616 DB01419] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC;PTGS1 GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0070542| response to fatty acid PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0014070| response to organic cyclic compound PTGS2;LYN 6099:[DB06616 DB00887] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0006813| potassium ion transport CDK2;SLC12A4;SLC12A2;SLC12A5;SLC12A1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0006810| transport SLC12A2;SLC12A4;SLC10A1;ABCB1;SLC12A1 GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0009636| response to toxin LYN;SLC22A8 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0055085| transmembrane transport SLC10A1;ABCB1;SLC22A11;SLC12A5;SLC22A7;SLC12A1;SLCO1A2;CFTR;SLC22A6;SLC12A2;SLC22A8;SLC12A4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;SRC;ABL1 GO:0006954| inflammatory response PTGS2;LYN;HCK GO:0016032| viral reproduction LYN;SRC;HCK;SLC10A1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0042493| response to drug SLC12A5;SRC;ABCB1;LYN;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC 6100:[DB06616 DB00756] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0007165| signal transduction ESR1;LYN;SRC;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0055114| oxidation-reduction process SDHD;CYP3A4;GLUD1;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;SRC;MAP2K2;MAP2K1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0060065| uterus development SRC;ESR1 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 6101:[DB06616 DB04450] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04450|Heptyl 1-Thiohexopyranoside RHO;fpr;acpP common genes common pathways GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;RHO;MAP3K2;CAMK2G;CDK2;LYN GO:0007165| signal transduction LYN;RHO;MAP2K1;BCR;SRC 6102:[DB06616 DB07626] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07626|4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0007596| blood coagulation LYN;PLAU GO:0030335| positive regulation of cell migration PLAU;LYN GO:0007165| signal transduction PLAU;SRC;BCR;MAP2K1;LYN GO:0042127| regulation of cell proliferation SRC;ABL1;PLAU GO:0006935| chemotaxis PLAU;MAP2K1 6103:[DB06616 DB01689] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01689|Inhibitor Idd 384 AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0043066| negative regulation of apoptotic process AKR1B1;SRC;HCK GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 6104:[DB06616 DB09325] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways GO:0051602| response to electrical stimulus MT-CO1;SRC GO:0055114| oxidation-reduction process CYP2C8;MT-CO1;CYP3A4 GO:0006979| response to oxidative stress ABL1;MT-CO1 6105:[DB06616 DB00115] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;CUBN GO:0009791| post-embryonic development ABL1;MUT GO:0043200| response to amino acid stimulus MTHFR;LYN GO:0070555| response to interleukin-1 MTHFR;SRC GO:0043547| positive regulation of GTPase activity BCR;MUT GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CUBN GO:0055114| oxidation-reduction process MMACHC;CYP2C8;MTRR;CYP3A4;MTHFR GO:0042493| response to drug ABCB1;SRC;MTHFR;LYN GO:0006629| lipid metabolic process CUBN;CYP3A4 GO:0007399| nervous system development CAMK2G;MTR GO:0006897| endocytosis ABL1;CUBN GO:0071732| cellular response to nitric oxide CDK2;MTR GO:0007275| multicellular organismal development CDK2;AMN;CAMK2G GO:0048678| response to axon injury LYN;MTR 6106:[DB06616 DB08257] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways GO:0009636| response to toxin LYN;EPHX2 GO:0010628| positive regulation of gene expression EPHX2;MAP2K1;SRC GO:0017144| drug metabolic process EPHX2;CYP3A4;CYP2C8 GO:0006954| inflammatory response LYN;EPHX2;HCK GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;EPHX2 6107:[DB06616 DB04721] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04721|N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:1901796| CDK2;CSNK2A1 GO:0008284| positive regulation of cell proliferation HCK;CSNK2A1;LYN;CDK2 GO:0007049| cell cycle SRC;CDK2;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CSNK2A1;CAMK2G GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0007165| signal transduction LYN;CSNK2A1;BCR;SRC;MAP2K1 GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;CSNK2A1;MAP3K2;CDK2;LYN;CAMK2G GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;CSNK2A1;MAP3K2;LYN;CDK2;CAMK2G 6108:[DB06616 DB07991] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways GO:0007165| signal transduction ESR1;LYN;BCR;SRC;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0060065| uterus development ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;ESR1;MAP3K2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 6109:[DB06616 DB05298] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05298|Tetomilast PDE4D common genes common pathways GO:0007165| signal transduction PDE4D;LYN;MAP2K1;BCR;SRC GO:0050900| leukocyte migration PDE4D;LYN;SRC GO:0071222| cellular response to lipopolysaccharide PDE4D;ABL1;BCR;SRC 6110:[DB06616 DB07030] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07030|(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance CDK2;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;SRC;HCK GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 6111:[DB06616 DB05562] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05562|Naluzotan HTR1A common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;HTR1A;LYN GO:0008283| cell proliferation SRC;HTR1A GO:0008284| positive regulation of cell proliferation HTR1A;CDK2;LYN;HCK 6112:[DB06616 DB04339] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04339|Carbocisteine GSTP1 common genes common pathways GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0032869| cellular response to insulin stimulus GSTP1;SRC GO:0007417| central nervous system development GSTP1;SRC;LYN GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;GSTP1;MAP2K1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0009636| response to toxin GSTP1;LYN GO:0071222| cellular response to lipopolysaccharide GSTP1;SRC;BCR;ABL1 GO:0006805| xenobiotic metabolic process CYP2C8;GSTP1;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;GSTP1;HCK GO:0034599| cellular response to oxidative stress ABL1;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0014003| oligodendrocyte development GSTP1;LYN GO:0031667| response to nutrient levels GSTP1;SRC 6113:[DB06616 DB05101] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05101|Matuzumab EGFR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;EGFR GO:0014070| response to organic cyclic compound EGFR;LYN GO:0008283| cell proliferation SRC;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;SRC GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0046777| protein autophosphorylation ABL1;EGFR;HCK;SRC;BCR;LYN;CAMK2G GO:0000186| activation of MAPKK activity MAP3K2;EGFR GO:0045930| negative regulation of mitotic cell cycle EGFR;ABL1 GO:0006468| protein phosphorylation MAP2K1;HCK;EGFR;BCR;MAP2K2;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:1903800| MAP2K2;EGFR;MAP2K1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EGFR;HCK;LYN GO:0098609| SRC;EGFR GO:0030335| positive regulation of cell migration EGFR;LYN GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;EGFR;HCK;CAMK2G;LYN;CDK2;MAP3K2 GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;LYN GO:0007165| signal transduction LYN;MAP2K1;EGFR;BCR;SRC GO:0006979| response to oxidative stress ABL1;EGFR GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;EGFR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;EGFR;MAP2K2;SRC;MAP3K2;CDK2 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;EGFR GO:0038083| LYN;HCK;EGFR;SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;EGFR GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;EGFR;MAP2K2 GO:0038128| EGFR;SRC GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;EGFR;ABL1;LYN GO:0007275| multicellular organismal development CAMK2G;CDK2;EGFR GO:0042127| regulation of cell proliferation EGFR;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0042327| positive regulation of phosphorylation LYN;EGFR GO:0043066| negative regulation of apoptotic process SRC;EGFR;HCK GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;EGFR GO:2000145| regulation of cell motility EGFR;ABL1 GO:0008284| positive regulation of cell proliferation EGFR;HCK;LYN;CDK2 6114:[DB06616 DB07242] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07242|(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile DAPK3;PIM1 common genes common pathways GO:0007346| regulation of mitotic cell cycle PIM1;MAP3K2;MAP2K2;MAP2K1;DAPK3 GO:0006355| regulation of transcription, DNA-dependent DAPK3;ABL1 GO:0010506| regulation of autophagy ABL1;DAPK3 GO:0007275| multicellular organismal development PIM1;CAMK2G;CDK2 GO:0043065| positive regulation of apoptotic process ABL1;DAPK3;SRC GO:0018105| peptidyl-serine phosphorylation DAPK3;SRC;CDK2;CAMK2G GO:2000249| regulation of actin cytoskeleton reorganization ABL1;DAPK3 GO:2000145| regulation of cell motility DAPK3;ABL1 GO:0035556| intracellular signal transduction DAPK3;SRC;BCR;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;PIM1 GO:0008360| regulation of cell shape DAPK3;HCK GO:0042981| regulation of apoptotic process DAPK3;MAP2K1;MAP2K2;MAP3K2 GO:0030182| neuron differentiation DAPK3;ABL1;MAP2K1 GO:0008283| cell proliferation SRC;PIM1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;DAPK3;MAP2K1 GO:0006915| apoptotic process PIM1;ABL1;DAPK3 GO:0046777| protein autophosphorylation CAMK2G;LYN;PIM1;ABL1;DAPK3;BCR;SRC;HCK GO:0090263| positive regulation of canonical Wnt receptor signaling pathway DAPK3;SRC GO:0007049| cell cycle CDK2;PIM1;SRC GO:0016310| phosphorylation MAP3K2;PIM1;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;DAPK3;ABL1 GO:0030335| positive regulation of cell migration DAPK3;LYN GO:0006468| protein phosphorylation DAPK3;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;PIM1 6115:[DB06616 DB06454] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;LYN GO:0030336| negative regulation of cell migration DRD2;BCR GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;DRD2;SRC;MAP2K1;ABL1 GO:0008283| cell proliferation HTR1A;SRC GO:0009636| response to toxin LYN;DRD2 GO:0007165| signal transduction SRC;DRD2;BCR;MAP2K1;HTR1A;DRD3;LYN GO:0030900| forebrain development SRC;DRD2 GO:0042493| response to drug DRD3;LYN;DRD2;SRC;ABCB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DRD3 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DRD3;HTR1A GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC;DRD2 GO:0048678| response to axon injury DRD2;LYN 6116:[DB06616 DB08389] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;PDE10A 6117:[DB06616 DB00677] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0008283| cell proliferation SRC;ACHE GO:0006260| DNA replication CDK2;ACHE GO:0042493| response to drug SRC;ABCB1;BCHE;LYN GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ACHE;SRC;HCK;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation ALB;LYN;TF 6118:[DB06616 DB05806] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05806|Cositecan TOP1 common genes common pathways GO:0016310| phosphorylation LYN;CDK2;CAMK2G;TOP1;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0018105| peptidyl-serine phosphorylation SRC;TOP1;CAMK2G;CDK2 GO:0006260| DNA replication TOP1;CDK2 GO:0016032| viral reproduction TOP1;LYN;HCK;SRC GO:0042493| response to drug SRC;ABCB1;LYN;TOP1 6119:[DB06616 DB04633] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways GO:0042127| regulation of cell proliferation SAT1;ABL1;SRC 6120:[DB06616 DB13926] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13926|Cenegermin NTRK1 common genes common pathways GO:0000186| activation of MAPKK activity NTRK1;MAP3K2 GO:0030154| cell differentiation HCK;CAMK2G;NTRK1 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;NTRK1;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;NTRK1;HCK GO:0043547| positive regulation of GTPase activity BCR;NTRK1 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;NTRK1;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0008285| negative regulation of cell proliferation MAP2K1;NTRK1;LYN GO:0007411| axon guidance SRC;NTRK1 GO:0048013| ephrin receptor signaling pathway SRC;LYN;NTRK1 GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;LYN;NTRK1;CAMK2G GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;NTRK1 GO:0007399| nervous system development NTRK1;CAMK2G GO:0043066| negative regulation of apoptotic process NTRK1;HCK;SRC GO:0048678| response to axon injury NTRK1;LYN GO:0018108| peptidyl-tyrosine phosphorylation LYN;NTRK1;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0007275| multicellular organismal development CAMK2G;NTRK1;CDK2 GO:0051602| response to electrical stimulus SRC;NTRK1 GO:0010976| positive regulation of neuron projection development NTRK1;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;NTRK1;LYN GO:0048011| nerve growth factor receptor signaling pathway NTRK1;SRC GO:0031667| response to nutrient levels NTRK1;SRC GO:0042493| response to drug NTRK1;LYN;ABCB1;SRC GO:0038083| LYN;NTRK1;ABL1;SRC;HCK 6121:[DB06616 DB11323] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug LYN;PTGS2;ABCB1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC 6122:[DB06616 DB03957] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03957|SP2456 IL2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation ABL1;IL2;LYN GO:0050728| negative regulation of inflammatory response IL2;BCR GO:0002250| adaptive immune response LYN;IL2 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;IL2;CAMK2G GO:0001933| negative regulation of protein phosphorylation LYN;IL2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;IL2;HCK GO:0043066| negative regulation of apoptotic process HCK;SRC;IL2 GO:0007155| cell adhesion SRC;HCK;ABL1;IL2 GO:0007204| elevation of cytosolic calcium ion concentration IL2;ABL1 GO:0002376| immune system process IL2;SRC;HCK;LYN GO:0065009| regulation of molecular function IL2;CAMK2G 6123:[DB06616 DB14544] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1;CYP3A4;CYP2C8 common pathways GO:0008209| androgen metabolic process CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A5;HSD11B2;HSD3B1;CYP2C8;CYP3A4;CYP3A7;CYP11B1;CYP11B2 GO:0099040| ABCB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;ANXA1 GO:0042493| response to drug SRC;ABCB1;HSD11B2;ABCG2;ANXA1;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0006909| phagocytosis HCK;ANXA1;ABL1 GO:0002250| adaptive immune response LYN;ANXA1 GO:0006954| inflammatory response HCK;ANXA1;LYN GO:0051301| cell division NR3C1;CDK2 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0042127| regulation of cell proliferation ABL1;ANXA1;SRC GO:0046483| heterocycle metabolic process CYP3A4 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008360| regulation of cell shape ANXA1;HCK GO:0045087| innate immune response ANXA1;ABL1;SRC;HCK;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0006082| organic acid metabolic process CYP2C8 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4 GO:0030073| insulin secretion ANXA1;CAMK2G GO:0006706| steroid catabolic process CYP3A4 GO:0043065| positive regulation of apoptotic process ABL1;ANXA1;SRC GO:0050727| regulation of inflammatory response ANXA1;HCK;LYN GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0043066| negative regulation of apoptotic process HCK;SRC;ANXA1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0032868| response to insulin stimulus LYN;HSD11B2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCG2;ABCB1 GO:0036378| CYP3A4 GO:0006915| apoptotic process NR3C1;ABL1 GO:0030216| keratinocyte differentiation MAP2K1;ANXA1 GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0009636| response to toxin LYN;SLC22A8 GO:0014070| response to organic cyclic compound ANXA1;LYN GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0070301| cellular response to hydrogen peroxide ANXA1;ABL1 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0046632| alpha-beta T cell differentiation ABL1;ANXA1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0098609| ANXA1;SRC GO:0043434| response to peptide hormone stimulus ANXA1;LYN GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP3A7;CYP11B2;CYP11B1;CYP3A4 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007165| signal transduction MAP2K1;SRC;BCR;ANXA1;NR3C1;LYN GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0097267| CYP2C8 GO:0009725| response to hormone stimulus LYN;ANXA1 GO:0070555| response to interleukin-1 SRC;ANXA1 GO:0002376| immune system process LYN;SRC;HCK;ANXA1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP3A5 6124:[DB06616 DB14481] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1;CIB1 GO:0055085| transmembrane transport TRPV6;SLC20A1;CACNA1G;TRPV5;CACNA1S;CATSPER1;CACNA1H;RYR3;CACNA1E;CALM1;SLC20A2;CACNA1A;CACNA1I;ABCB1;SLC8A1;CACNA1D;SLC34A3;RYR1;RYR2;CACNA1F;CACNA1C;SLC34A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;CIB1;MAP2K1;SRC;MAP2K2 GO:0006915| apoptotic process PDCD6;CIB1;CASR;ABL1 GO:0038095| CALM1;LYN GO:0008283| cell proliferation SRC;S100B GO:0014070| response to organic cyclic compound CASR;LYN GO:0050663| cytokine secretion S100A13;LYN GO:0007411| axon guidance NRXN1;SRC GO:0010033| response to organic substance CDK2;CASQ1;CALR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;CIB1 GO:0007049| cell cycle CDK2;CIB1;SRC GO:0050766| positive regulation of phagocytosis CALR;BCR GO:0045892| negative regulation of transcription, DNA-dependent SRC;CALR GO:0071902| positive regulation of protein serine/threonine kinase activity CALM2;CALM1;CALM3;MAP2K2;SRC;MAP2K1;CIB1 GO:0010628| positive regulation of gene expression CALR;CASR;MAP2K1;SRC GO:0034614| cellular response to reactive oxygen species SRC;SLC8A1 GO:0030154| cell differentiation CIB1;HCK;TPT1;CALR3;CAMK2G;CATSPER1 GO:0071456| cellular response to hypoxia SLC8A1;SRC;S100B;CASR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CACNA1C;CACNA1A;SLC8A1;CIB2 GO:0006810| transport CACNB4;CACNA1I;ABCB1;CACNB1;SLC20A2;CACNA1E;SRI;SLC20A1;CACNB3 GO:0010595| positive regulation of endothelial cell migration ABL1;SPARC;PDCD6;CALR GO:0007417| central nervous system development S100B;SRC;LYN GO:0043547| positive regulation of GTPase activity BCR;RGN GO:0030335| positive regulation of cell migration LYN;CIB1 GO:0034605| cellular response to heat PDCD6;LYN GO:0043434| response to peptide hormone stimulus LYN;SPARC;SLC34A1 GO:0006887| exocytosis CADPS;HCK;CADPS2 GO:0007165| signal transduction CASR;SPARC;S100A6;SRC;CACNA1I;BCR;MAP2K1;SLC20A1;LYN;SRI GO:0010907| positive regulation of glucose metabolic process SRC;RGN GO:0051222| positive regulation of protein transport CHP1;SRC GO:0065009| regulation of molecular function CAMK2G;NRXN1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol SRI;CASQ1;ABL1 GO:1900026| CIB1;ABL1;CALR GO:0006813| potassium ion transport CDK2;CHP1 GO:0050885| neuromuscular process controlling balance ABL1;BCR;NRXN1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;CIB1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;CIB1 GO:0042493| response to drug LYN;CALR;SLC34A1;SRC;SLC8A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent CALR;ABL1 GO:0031954| positive regulation of protein autophosphorylation CALM2;CALM3;CALM1;SRC GO:0051924| regulation of calcium ion transport CASR;SLC8A1;CAMK2G;SRI GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CALM1;CAMK2G GO:0051602| response to electrical stimulus S100A13;SRC GO:0016032| viral reproduction SLC20A2;HCK;SRC;LYN GO:0006816| calcium ion transport PKD1L3;CACNB1;CASR;RYR1;RYR2;CACNA1F;CACNA1C;CACNA1A;CACNA1I;SLC8A1;CACNA1D;CACNB4;CACNB3;TPT1;TRPV6;CAMK2G;CACNB2;RYR3;SRI;CACNA1E;PKD2L1;CACNA1G;TRPV5;CATSPER1;CACNA1S;CACNA1H GO:0090398| cellular senescence CALR;MAP2K1 GO:0051301| cell division CDK2;CIB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;S100B;S100A13;ABL1 GO:0007275| multicellular organismal development CDK2;CAMK2G;CATSPER1;RYR1;RYR2 GO:0051259| protein oligomerization CAMK2G;CHP1 GO:0042127| regulation of cell proliferation CIB1;SRC;ABL1;SPARC GO:0032496| response to lipopolysaccharide SPARC;BCR GO:0001933| negative regulation of protein phosphorylation RGN;LYN;CIB1;CHP1 GO:0007507| heart development SPARC;MAP2K1;CACNA1C;SRI GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;CDK2 GO:0045087| innate immune response S100B;HCK;SRC;ABL1;LYN GO:0007155| cell adhesion NRXN1;ABL1;CIB1;HCK;SRC GO:0008360| regulation of cell shape HCK;S100B;S100A13 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;TPT1;CALR;MAP3K2 GO:0006974| response to DNA damage stimulus CIB1;ABL1;LYN;CDK2 GO:0043065| positive regulation of apoptotic process S100B;SRC;ABL1 GO:0002576| platelet degranulation SPARC;CALM1;ALB;LYN GO:0009615| response to virus SRC;TPT1 GO:0042542| response to hydrogen peroxide SLC8A1;SRC GO:0008284| positive regulation of cell proliferation CALR;LYN;CDK2;HCK;CIB1;S100B;S100A13;CASR GO:0035556| intracellular signal transduction SRC;CAPS;BCR;CAMK2G;LYN GO:0043066| negative regulation of apoptotic process RGN;TPT1;SRC;HCK;CIB1;ALB 6125:[DB06616 DB06401] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06401|Bazedoxifene ESR1;ESR2;UGT1A8;UGT1A10 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;ESR2;MAP3K2;CDK2;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1;ESR2 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;ESR1;MAP3K2 GO:0060065| uterus development SRC;ESR1 GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0017144| drug metabolic process CYP2C8;UGT1A10;UGT1A8;CYP3A4 GO:0007165| signal transduction LYN;ESR1;ESR2;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A8;CYP3A4 6126:[DB06616 DB08102] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways GO:0006810| transport ABCB1;TTR 6127:[DB06616 DB07020] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;MAPK9 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;MAPK9;CAMK2G;MAP3K2 GO:0016310| phosphorylation MAP3K2;LYN;CDK2;MAPK9;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0034614| cellular response to reactive oxygen species SRC;MAPK9 GO:0010628| positive regulation of gene expression MAP2K1;SRC;MAPK9 GO:0038095| MAPK9;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G;MAPK9 GO:0043065| positive regulation of apoptotic process ABL1;SRC;MAPK9 GO:0009612| response to mechanical stimulus SRC;MAPK9 GO:0071803| positive regulation of podosome assembly MAPK9;SRC 6128:[DB06616 DB05739] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways GO:0006954| inflammatory response AGTR2;HCK;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;SRC;MAP2K2;MAP2K1;AGTR2 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;AGTR2;MAP3K2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;AGTR2;HCK GO:0050727| regulation of inflammatory response LYN;HCK;AGTR1 GO:0035556| intracellular signal transduction AGTR2;BCR;SRC;CAMK2G;LYN GO:0042127| regulation of cell proliferation ABL1;AGTR1;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;AGTR2;AGTR1;LYN GO:0007420| brain development BCR;AGTR2 GO:0050715| positive regulation of cytokine secretion SRC;AGTR2 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ABL1 6129:[DB06616 DB08927] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08927|Amperozide HTR2A common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;HTR2A;LYN GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0042493| response to drug HTR2A;LYN;ABCB1;SRC GO:0008284| positive regulation of cell proliferation HCK;HTR2A;LYN;CDK2 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;ABL1;MAP2K1;MAP2K2;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A 6130:[DB06616 DB05966] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05966|TAS-108 ESR1;ESR2 common genes common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2;ESR1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0050727| regulation of inflammatory response HCK;ESR1;LYN GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2;SRC GO:0060065| uterus development ESR1;SRC GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;MAP2K2;SRC;MAP2K1;ESR2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction LYN;ESR1;ESR2;MAP2K1;BCR;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 6131:[DB06616 DB00017] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00017|Salmon Calcitonin CALCR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CALCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CALCR GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;CALCR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;CALCR GO:0010628| positive regulation of gene expression SRC;MAP2K1;CALCR 6132:[DB06616 DB04200] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04200|Matairesinol DHRS4L2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHRS4L2;CYP3A4 6133:[DB06616 DB08263] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08263|N-(carboxycarbonyl)-D-phenylalanine HIF1AN common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;HIF1AN GO:0055114| oxidation-reduction process HIF1AN;CYP3A4;CYP2C8 6134:[DB06616 DB08487] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08487|3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 6135:[DB06616 DB13757] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13757|Epanolol CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 6136:[DB06616 DB07306] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways GO:0042127| regulation of cell proliferation SRC;ABL1;NOS2 GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;BCR;SRC GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 6137:[DB06616 DB01427] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0051222| positive regulation of protein transport SRC;TNF GO:0007165| signal transduction PDE3A;LYN;MAP2K1;BCR;SRC;PDE4B GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0010033| response to organic substance TNF;CDK2 GO:0010628| positive regulation of gene expression TNF;MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;TNF GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0000187| activation of MAPK activity TNF;MAP3K2;MAP2K1;MAP2K2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0006629| lipid metabolic process PDE3A;CYP3A4 GO:0009615| response to virus SRC;TNF GO:0071222| cellular response to lipopolysaccharide TNF;BCR;SRC;PDE4B;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;TNF GO:0050727| regulation of inflammatory response HCK;LYN;TNF GO:0071560| cellular response to transforming growth factor beta stimulus PDE3A;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;LYN;HCK GO:0043066| negative regulation of apoptotic process PDE3A;SRC;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0042127| regulation of cell proliferation TNF;SRC;ABL1 GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0071803| positive regulation of podosome assembly SRC;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0000165| MAPKKK cascade TNF;CAMK2G;MAP2K1;MAP2K2 GO:0006954| inflammatory response LYN;TNF;HCK GO:0050900| leukocyte migration TNF;LYN;SRC;PDE4B GO:0001934| positive regulation of protein phosphorylation ABL1;TNF;LYN GO:0042493| response to drug ABCB1;SRC;PDE3A;LYN GO:0010629| negative regulation of gene expression TNF;MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;TNF;MAP2K1;MAP2K2;SRC 6138:[DB06616 DB12319] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12319|Benzbromarone CYP2C9;CYP2C19;CYP2C19;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C19;CYP2C8 GO:0006810| transport ABCB1;ABCB11 GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLCO1B1;ABCB11 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2C19 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C19;CYP2C8 6139:[DB06616 DB05488] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug LYN;CYP1A2;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0030900| forebrain development TOP2B;SRC GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 6140:[DB06616 DB03577] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways 6141:[DB06616 DB06525] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06525|Ganstigmine ACHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007155| cell adhesion SRC;HCK;ABL1;ACHE GO:0007399| nervous system development ACHE;CAMK2G GO:0006260| DNA replication ACHE;CDK2 6142:[DB06616 DB00173] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRPK2;SRC GO:0010033| response to organic substance UGT1A1;CDK2 GO:0014070| response to organic cyclic compound ACACB;LYN;UGT1A1 GO:0006470| protein dephosphorylation CAMK2G;ACP1 GO:0017144| drug metabolic process CYP2C8;CYP3A4;UGT1A1 GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;SRPK2;ABL1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0032869| cellular response to insulin stimulus SRC;APRT GO:0030154| cell differentiation CAMK2G;SRPK2;HCK GO:0006468| protein phosphorylation BCR;MAP2K2;SRPK2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0042493| response to drug ABCB1;ACACB;SRC;UGT1A1;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ACACB GO:0031667| response to nutrient levels SRC;ACACB GO:0055114| oxidation-reduction process CYP2C8;PECR;CYP3A4 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;SRPK2 GO:0035556| intracellular signal transduction SRPK2;SRC;BCR;LYN;CAMK2G GO:0045087| innate immune response SRC;SRPK2;HCK;ABL1;LYN GO:0006629| lipid metabolic process ACACB;PECR;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 6143:[DB06616 DB09006] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0042127| regulation of cell proliferation PPARD;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;CDK2;PPARA;PPARG GO:0045087| innate immune response SRC;HCK;ABL1;PPARG;LYN GO:0007507| heart development MAP2K1;PPARA;PPARG;PPARD GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4;PPARD GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PPARD GO:0008284| positive regulation of cell proliferation PPARD;LYN;CDK2;HCK GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;PPARD GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG;PPARD;ABL1 GO:0042493| response to drug LYN;PPARG;SRC;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG;PPARA;PPARD;MAP3K2;MAP2K1;MAP2K2;SRC GO:0050728| negative regulation of inflammatory response PPARD;PPARA;BCR GO:0071456| cellular response to hypoxia SRC;PPARD GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0030154| cell differentiation PPARD;CAMK2G;HCK GO:0007165| signal transduction PPARG;LYN;BCR;SRC;MAP2K1 GO:0032868| response to insulin stimulus PPARA;LYN GO:0006915| apoptotic process ABL1;PPARD GO:0008283| cell proliferation PPARD;SRC GO:0014070| response to organic cyclic compound PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARD;PPARG GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1 GO:0010033| response to organic substance PPARD;CDK2;PPARG GO:0010628| positive regulation of gene expression SRC;MAP2K1;PPARD 6144:[DB06616 DB00979] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;CHRM1;CDK2;LYN GO:0007399| nervous system development CHRM1;CAMK2G GO:0042493| response to drug SRC;ABCB1;BCHE;LYN GO:0007165| signal transduction CHRM1;LYN;SRC;BCR;MAP2K1 GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0006464| protein modification process ABL1;CHRM1 GO:0008283| cell proliferation SRC;CHRM1 6145:[DB06616 DB07577] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug LYN;TYMS;SRC;ABCB1 GO:0009636| response to toxin TYMS;LYN GO:0014070| response to organic cyclic compound TYMS;LYN 6146:[DB06616 DB07489] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07489|4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium CSNK1G3 common genes common pathways GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;CSNK1G3 GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;CSNK1G3;MAP3K2;CAMK2G;CDK2;LYN GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;CSNK1G3 GO:0006464| protein modification process CSNK1G3;ABL1 GO:0008360| regulation of cell shape HCK;CSNK1G3 GO:0018105| peptidyl-serine phosphorylation CSNK1G3;SRC;CAMK2G;CDK2 GO:0006897| endocytosis ABL1;CSNK1G3 6147:[DB06616 DB02811] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02811|Diethylphosphono Group BCHE;fbpC;BCHE common genes common pathways GO:0042493| response to drug LYN;BCHE;ABCB1;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN 6148:[DB06616 DB04847] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04847|Roxadustat EGLN1;EGLN2;EGLN3 common genes common pathways GO:0055114| oxidation-reduction process EGLN2;EGLN1;CYP2C8;EGLN3;CYP3A4 GO:0042127| regulation of cell proliferation ABL1;EGLN3;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC;EGLN2 GO:0006974| response to DNA damage stimulus ABL1;EGLN3;LYN;CDK2 GO:0060711| labyrinthine layer development EGLN1;MAP2K1 GO:0006915| apoptotic process EGLN3;ABL1 6149:[DB06616 DB09369] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09369|Polyestradiol phosphate ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0060065| uterus development SRC;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 6150:[DB06616 DB08734] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0009636| response to toxin LYN;TYMS GO:0014070| response to organic cyclic compound TYMS;LYN GO:0042493| response to drug SRC;ABCB1;LYN;TYMS 6151:[DB06616 DB09116] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0032868| response to insulin stimulus LYN;CAT GO:0009636| response to toxin LYN;CAT GO:0070542| response to fatty acid CAT;SRC GO:0006979| response to oxidative stress ABL1;CAT GO:0055114| oxidation-reduction process CYP3A4;ALDH3B2;CAT;CYP2C8 GO:0042493| response to drug LYN;SRC;ABCB1;CAT GO:0034599| cellular response to oxidative stress CAT;ABL1 GO:0006629| lipid metabolic process ALDH3B2;CYP3A4 GO:0043066| negative regulation of apoptotic process HCK;SRC;CAT GO:0042542| response to hydrogen peroxide SRC;CAT 6152:[DB06616 DB09347] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09347|Acetrizoic acid ALB common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation ALB;LYN 6153:[DB06616 DB09109] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09109|Turoctocog alfa F9;F10;F2 common genes common pathways GO:0051281| positive regulation of release of sequestered calcium ion into cytosol F2;ABL1 GO:1900182| SRC;F2 GO:0030335| positive regulation of cell migration F10;LYN GO:0030168| platelet activation SRC;F2;LYN GO:0007596| blood coagulation F2;F9;LYN;F10 GO:0008284| positive regulation of cell proliferation HCK;F2;LYN;CDK2 GO:0008360| regulation of cell shape F2;HCK GO:0007275| multicellular organismal development CDK2;CAMK2G;F2 GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0001934| positive regulation of protein phosphorylation LYN;F2;ABL1 GO:0050900| leukocyte migration LYN;SRC;F2 6154:[DB06616 DB05029] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05029|Lancovutide PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;CYP3A4 GO:0042127| regulation of cell proliferation PLA2G4A;ABL1;SRC 6155:[DB06616 DB13520] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13520|Metergoline SCN2A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN2A GO:0007399| nervous system development CAMK2G;SCN2A 6156:[DB06616 DB08369] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP2C8;CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2B6 GO:0055114| oxidation-reduction process CYP2C8;CYP2B6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6 6157:[DB06616 DB08348] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08348|N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE EEF2;PARP3;PARP15 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PARP15 GO:0042493| response to drug SRC;ABCB1;EEF2;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PARP15 GO:0006281| DNA repair ABL1;CDK2;PARP3 GO:0042542| response to hydrogen peroxide SRC;EEF2 6158:[DB06616 DB05876] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05876|PDE4 PDE4A common genes common pathways GO:0007165| signal transduction LYN;PDE4A;MAP2K1;SRC;BCR 6159:[DB06616 DB02431] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways GO:0016310| phosphorylation MAP2K1;HCK;UCK2;MAP2K2;BCR;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G 6160:[DB06616 DB09059] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0008284| positive regulation of cell proliferation AVPR2;HCK;CDK2;LYN;AVPR1A GO:0007507| heart development MAP2K1;OXTR GO:0042493| response to drug ABCB1;SRC;OXTR;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2;OXTR GO:0043434| response to peptide hormone stimulus OXTR;LYN GO:0007204| elevation of cytosolic calcium ion concentration AVPR1B;OXTR;AVPR1A;ABL1 GO:0007165| signal transduction MAP2K1;AVPR2;SRC;BCR;AVPR1B;OXTR;LYN;AVPR1A GO:0014070| response to organic cyclic compound LYN;OXTR GO:0010628| positive regulation of gene expression MAP2K1;AVPR2;SRC GO:0010033| response to organic substance AVPR1A;CDK2 6161:[DB06616 DB07902] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07902|TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE METAP1 common genes common pathways 6162:[DB06616 DB01454] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K1;MAP2K2 GO:0016032| viral reproduction LYN;HTR2A;SRC;HCK GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0042493| response to drug SLC6A2;LYN;HTR2A;SRC;ABCB1;SLC6A3;SLC6A4;HTR2B;HTR2C GO:0007507| heart development MAP2K1;HTR2B GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HTR2B;HCK;CDK2;LYN;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;HCK;SRC GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC;HTR2B GO:0010033| response to organic substance CDK2;SLC6A4 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0055085| transmembrane transport SLC18A2;SLC6A2;SLC6A4;SLC6A3;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;SRC;MAP2K2;MAP2K1;ABL1;HTR2C;HTR2B GO:0009636| response to toxin LYN;SLC18A2;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007165| signal transduction LYN;HTR2A;HTR2C;HTR2B;SRC;BCR;MAP2K1 GO:0007420| brain development BCR;SLC6A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0050715| positive regulation of cytokine secretion SRC;HTR2B GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0006810| transport SLC6A2;ABCB1 GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;HTR2B;MAP3K2;CAMK2G;LYN;CDK2 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0043547| positive regulation of GTPase activity HTR2B;BCR 6163:[DB06616 DB08072] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08072|4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE PLAU common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;PLAU;LYN GO:0030335| positive regulation of cell migration PLAU;LYN GO:0007596| blood coagulation PLAU;LYN GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0006935| chemotaxis PLAU;MAP2K1 GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC 6164:[DB06616 DB00914] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;PRKAA1;MAP2K2;BCR GO:0071456| cellular response to hypoxia PRKAA1;SRC GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;PRKAA1;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0008202| steroid metabolic process PRKAA1;CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction LYN;MAP2K1;SRC;PRKAA1;BCR GO:0007050| cell cycle arrest MAP2K1;PRKAA1;ABL1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0006813| potassium ion transport CDK2;KCNJ8 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0055085| transmembrane transport ABCB1;SLC22A2;SLC22A1 GO:0000187| activation of MAPK activity MAP3K2;PRKAA1;MAP2K2;MAP2K1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070301| cellular response to hydrogen peroxide ABL1;PRKAA1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;PRKAA1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0032496| response to lipopolysaccharide BCR;KCNJ8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0007507| heart development MAP2K1;KCNJ8 GO:0006629| lipid metabolic process CYP3A4;PRKAA1;CYP2D6 GO:1901796| CDK2;PRKAA1 GO:0042542| response to hydrogen peroxide SRC;PRKAA1 GO:0008284| positive regulation of cell proliferation HCK;PRKAA1;CDK2;LYN GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0043066| negative regulation of apoptotic process HCK;PRKAA1;SRC GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0006914| autophagy PRKAA1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PRKAA1 GO:0016236| macroautophagy PRKAA1;SRC 6165:[DB06616 DB07221] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways 6166:[DB06616 DB01956] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:1901216| ABL1;GRIN2B GO:0042493| response to drug SRC;ABCB1;GABRG3;LYN GO:0000165| MAPKKK cascade CAMK2G;GRIN2B;MAP2K2;MAP2K1 GO:0006629| lipid metabolic process BAAT;CYP3A4 GO:0009636| response to toxin GABRB1;LYN GO:0043200| response to amino acid stimulus LYN;GLRA3 GO:0055085| transmembrane transport ABCB1;SLC36A1;SLC15A1 GO:0009791| post-embryonic development ABL1;GABRG2 GO:0048013| ephrin receptor signaling pathway GRIN2B;LYN;SRC GO:0007417| central nervous system development SRC;LYN;GABRA4 GO:0006810| transport GABRB3;ABCB1;SLC15A1;GABRA1;GABRA6;GABRA4;GRIN2B;GABRD;GABRB2;GABRA5;GABRG2;GABRB1;GABRA3;SLC6A6 GO:0065009| regulation of molecular function GRIN2B;CAMK2G GO:0007165| signal transduction GABRB1;GABRA5;GABRQ;GABBR1;GABRE;GABRP;LYN;GABRA6;GABRD;MAP2K1;BCR;SRC;GABRB3 GO:0007420| brain development BCR;GABRA5 6167:[DB06616 DB02889] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02889|4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose AMY2A;AMY2A common genes common pathways 6168:[DB06616 DB00469] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0070542| response to fatty acid SRC;PTGS2 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0006979| response to oxidative stress ABL1;PTGS1;PTGS2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0055085| transmembrane transport ABCB1;SLC22A8 GO:0009636| response to toxin LYN;SLC22A8 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS2;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0008284| positive regulation of cell proliferation PTGS2;LYN;CDK2;HCK GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;CYP2C9;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK 6169:[DB06616 DB01780] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01780|Fusicoccin YWHAE common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle YWHAE;ABCB1;CDK2 GO:0034605| cellular response to heat LYN;YWHAE GO:1900034| YWHAE;CAMK2G GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process YWHAE;SRC GO:0010389| regulation of G2/M transition of mitotic cell cycle YWHAE;CDK2 GO:0000165| MAPKKK cascade YWHAE;MAP2K1;MAP2K2;CAMK2G GO:0016032| viral reproduction LYN;YWHAE;HCK;SRC GO:0035556| intracellular signal transduction SRC;BCR;YWHAE;LYN;CAMK2G 6170:[DB06616 DB04465] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways GO:0045087| innate immune response HCK;SRC;ABL1;LGALS3;LYN GO:0030154| cell differentiation LGALS3;CAMK2G;HCK GO:0002376| immune system process LYN;LGALS3;HCK;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway LGALS3;SRC 6171:[DB06616 DB01717] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways GO:0016310| phosphorylation ABL1;MAP2K1;HCK;AK1;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;AK8;MAP3K2;AK2 6172:[DB06616 DB07181] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0043542| endothelial cell migration DPP4;ABL1 GO:0007155| cell adhesion DPP4;ABL1;HCK;SRC GO:0008284| positive regulation of cell proliferation DPP4;CDK2;LYN;HCK 6173:[DB06616 DB12887] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12887|Tazemetostat EZH2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;EZH2 GO:0042127| regulation of cell proliferation SRC;ABL1;EZH2 GO:0001932| regulation of protein phosphorylation MAP2K1;EZH2;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;EZH2 GO:0006355| regulation of transcription, DNA-dependent ABL1;EZH2 GO:0043547| positive regulation of GTPase activity EZH2;BCR GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;EZH2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;EZH2 GO:0043406| positive regulation of MAP kinase activity EZH2;SRC GO:0070301| cellular response to hydrogen peroxide EZH2;ABL1 6174:[DB06616 DB11831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11831|Dinitrochlorobenzene MGMT;GSTP1 common genes common pathways GO:0006281| DNA repair MGMT;CDK2;ABL1 GO:0006974| response to DNA damage stimulus MGMT;CDK2;LYN;ABL1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;GSTP1 GO:0043066| negative regulation of apoptotic process HCK;GSTP1;SRC;MGMT GO:0071222| cellular response to lipopolysaccharide ABL1;GSTP1;SRC;BCR GO:0034599| cellular response to oxidative stress ABL1;GSTP1;MGMT GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0031667| response to nutrient levels GSTP1;SRC GO:0014003| oligodendrocyte development GSTP1;LYN GO:0042493| response to drug ABCB1;SRC;LYN;MGMT GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0032869| cellular response to insulin stimulus SRC;GSTP1 GO:0007417| central nervous system development LYN;GSTP1;SRC GO:0043407| negative regulation of MAP kinase activity GSTP1;LYN GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;GSTP1;MAP2K1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;ABL1;LYN GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0014070| response to organic cyclic compound LYN;MGMT GO:0009636| response to toxin LYN;MGMT;GSTP1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1 6175:[DB06616 DB02628] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02628|1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide XIAP common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;XIAP GO:0042127| regulation of cell proliferation SRC;ABL1;XIAP GO:0006974| response to DNA damage stimulus ABL1;XIAP;LYN;CDK2 GO:0043066| negative regulation of apoptotic process XIAP;HCK;SRC GO:0050727| regulation of inflammatory response XIAP;LYN;HCK GO:0006915| apoptotic process ABL1;XIAP GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;XIAP 6176:[DB06616 DB05744] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0007275| multicellular organismal development TNF;CDK2;CAMK2G GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL6;LYN GO:0042127| regulation of cell proliferation ABL1;SRC;TNF GO:0001932| regulation of protein phosphorylation MAP2K1;TNF;LYN GO:0032496| response to lipopolysaccharide IL10;BCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;IL6;TNF GO:0050727| regulation of inflammatory response LYN;TNF;HCK GO:0008284| positive regulation of cell proliferation HCK;IL6;CDK2;LYN GO:0009615| response to virus SRC;TNF GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;IL6;IL10;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;TNF;LYN GO:0043066| negative regulation of apoptotic process IL10;SRC;IL6;HCK GO:0050900| leukocyte migration SRC;TNF;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;TNF;LYN GO:0042493| response to drug LYN;IL10;SRC;ABCB1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;TNF GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;IL10;TNF;CDK2;MAP2K2;SRC;MAP2K1;IL6 GO:0019221| cytokine-mediated signaling pathway HCK;IL6 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;IL6;SRC;ABL1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0006954| inflammatory response CRP;IL10;TNF;LYN;HCK;IL6 GO:0050728| negative regulation of inflammatory response BCR;IL10 GO:0030889| negative regulation of B cell proliferation LYN;IL10 GO:0030168| platelet activation IL6;SRC;LYN GO:0045930| negative regulation of mitotic cell cycle ABL1;IL10;TNF GO:0051222| positive regulation of protein transport TNF;SRC GO:0030097| hemopoiesis IL10;LYN GO:0050715| positive regulation of cytokine secretion IL10;TNF;SRC GO:0045785| positive regulation of cell adhesion SRC;TNF GO:0042100| B cell proliferation IL10;ABL1 GO:0032868| response to insulin stimulus LYN;IL10 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ABL1;MAP2K1;MAP2K2;SRC GO:0000187| activation of MAPK activity MAP3K2;TNF;MAP2K1;MAP2K2 GO:0031175| neuron projection development LYN;IL6 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNF GO:2000352| negative regulation of endothelial cell apoptosis IL10;ABL1 GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0070301| cellular response to hydrogen peroxide IL6;ABL1 GO:0008285| negative regulation of cell proliferation IL10;LYN;IL6;MAP2K1 GO:0010033| response to organic substance IL10;TNF;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0010628| positive regulation of gene expression IL6;MAP2K1;SRC;CRP;TNF 6177:[DB06616 DB08078] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways GO:0050728| negative regulation of inflammatory response PPARD;BCR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARD;MAP3K2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARD GO:0043066| negative regulation of apoptotic process PPARD;SRC;HCK GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;PPARD GO:0008284| positive regulation of cell proliferation HCK;PPARD;CDK2;LYN GO:0006629| lipid metabolic process PPARD;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;CDK2 GO:0007507| heart development PPARD;MAP2K1 GO:0042127| regulation of cell proliferation PPARD;ABL1;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;SRC GO:0010033| response to organic substance PPARD;CDK2 GO:0008283| cell proliferation PPARD;SRC GO:0006915| apoptotic process ABL1;PPARD GO:0071456| cellular response to hypoxia PPARD;SRC GO:0030154| cell differentiation PPARD;CAMK2G;HCK 6178:[DB06616 DB05867] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 6179:[DB06616 DB12228] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CALCA;LYN;CDK2;CAMK2G GO:0007165| signal transduction MAP2K1;SRC;BCR;CALCB;LYN;CALCRL GO:0050728| negative regulation of inflammatory response CALCRL;BCR GO:0006816| calcium ion transport CAMK2G;CALCRL GO:0043542| endothelial cell migration ABL1;CALCA GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CALCRL GO:0007507| heart development CALCRL;MAP2K1 GO:0045087| innate immune response HCK;SRC;ABL1;LYN;CALCA 6180:[DB06616 DB00489] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0023014| signal transduction via phosphorylation event KCNH2;LYN GO:0007165| signal transduction LYN;ADRB2;SRC;ADRB1;BCR;MAP2K1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0006813| potassium ion transport CDK2;KCNH2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0045453| bone resorption SRC;ADRB2 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0055085| transmembrane transport KCNH2;ABCB1 6181:[DB06616 DB05003] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05003|Imexon RRM2;RRM1 common genes common pathways GO:0006260| DNA replication RRM2;RRM1;CDK2 GO:0055114| oxidation-reduction process CYP3A4;RRM1;CYP2C8;RRM2 GO:0000278| mitotic cell cycle RRM1;ABL1 GO:0051259| protein oligomerization CAMK2G;RRM1 6182:[DB06616 DB03667] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways GO:0006954| inflammatory response HCK;PTGS1;LYN GO:0055114| oxidation-reduction process PTGS1;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1 GO:0006979| response to oxidative stress ABL1;PTGS1 6183:[DB06616 DB02562] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02562|Quinonoid 7,8-Tetrahydrobiopterin PAH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PAH;CYP2C8 6184:[DB06616 DB00209] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0007399| nervous system development CAMK2G;CHRM1 GO:0008283| cell proliferation SRC;CHRM1 GO:0006464| protein modification process CHRM1;ABL1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;CHRM1 6185:[DB06616 DB00730] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0009615| response to virus SRC;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;LYN;CYP1A1;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4;CYP1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C8 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance CDK2;CYP1A1;CYP1A2 GO:0008283| cell proliferation SRC;CYP1A1 GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0014070| response to organic cyclic compound LYN;CYP1A1;CYP1A2 GO:0009636| response to toxin CYP1A1;LYN 6186:[DB06616 DB01963] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways 6187:[DB06616 DB03359] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways GO:0007155| cell adhesion ACHE;ABL1;SRC;HCK GO:0007399| nervous system development ACHE;CAMK2G GO:0006260| DNA replication CDK2;ACHE GO:0008283| cell proliferation ACHE;SRC 6188:[DB06616 DB04978] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04978|SP1049C TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;CDK2;LYN;ABL1 GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 6189:[DB06616 DB04419] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04419|D-norleucine PTH;HNF1A;PAH common genes common pathways GO:0030073| insulin secretion CAMK2G;HNF1A GO:0000122| negative regulation of transcription from RNA polymerase II promoter PTH;CDK2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;HNF1A;MAP3K2 GO:0031667| response to nutrient levels SRC;PTH GO:0006355| regulation of transcription, DNA-dependent HNF1A;ABL1 GO:0042493| response to drug SRC;ABCB1;LYN;PTH GO:0055114| oxidation-reduction process CYP2C8;PAH;CYP3A4 GO:0045453| bone resorption PTH;SRC 6190:[DB06616 DB05205] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05205|CX157 MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C8 6191:[DB06616 DB04090] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04090|RH-1 NQO1 common genes common pathways GO:0009636| response to toxin NQO1;LYN GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1 GO:0006979| response to oxidative stress ABL1;NQO1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NQO1 GO:0051602| response to electrical stimulus SRC;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;HCK;SRC GO:0006805| xenobiotic metabolic process NQO1;CYP3A4;CYP2C8 6192:[DB06616 DB08293] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08293|(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0006805| xenobiotic metabolic process HSP90AB1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process SRC;HCK;HSP90AB1 GO:0045597| positive regulation of cell differentiation MAP2K1;HSP90AB1 GO:0042493| response to drug LYN;HSP90AB1;SRC;ABCB1 GO:0038096| SRC;HCK;ABL1;HSP90AB1;LYN GO:1900034| CAMK2G;HSP90AB1 GO:0071902| positive regulation of protein serine/threonine kinase activity HSP90AB1;MAP2K1;SRC;MAP2K2 GO:0010033| response to organic substance HSP90AB1;CDK2 6193:[DB06616 DB02132] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02132|Zenarestat AKR1B1 common genes common pathways GO:0010033| response to organic substance CDK2;AKR1B1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;SRC;HCK 6194:[DB06616 DB00761] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0042493| response to drug SLC12A5;SRC;ABCB1;LYN GO:0006813| potassium ion transport SLC12A6;SLC12A1;SLC12A5;SLC12A2;SLC12A7;SLC12A4;CDK2 GO:0006810| transport ABCB1;SLC12A1;SLC12A7;SLC12A2;SLC12A4 GO:0055085| transmembrane transport SLC12A7;SLC12A2;SLC12A4;ABCB1;SLC12A6;SLC12A5;SLC12A1 6195:[DB06616 DB04426] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04426|Alpha-Methyl-N-Acetyl-D-Glucosamine MBL2 common genes common pathways GO:0045087| innate immune response SRC;HCK;ABL1;LYN;MBL2 GO:0002376| immune system process LYN;MBL2;HCK;SRC GO:0006979| response to oxidative stress ABL1;MBL2 GO:0050766| positive regulation of phagocytosis BCR;MBL2 6196:[DB06616 DB07251] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07251|N'-(3-CHLORO-4-METHOXY-PHENYL)-N-(3,4,5-TRIMETHOXYPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0048013| ephrin receptor signaling pathway SRC;EPHB4;LYN GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN;EPHB4 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;EPHB4;LYN;CDK2;CAMK2G;MAP3K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;EPHB4;LYN GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;EPHB4;LYN;CDK2 GO:0007155| cell adhesion EPHB4;SRC;HCK;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;EPHB4;LYN GO:0007275| multicellular organismal development EPHB4;CDK2;CAMK2G 6197:[DB06616 DB04983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04983|Denufosol P2RY2 common genes common pathways GO:0007165| signal transduction LYN;P2RY2;MAP2K1;SRC;BCR 6198:[DB06616 DB06137] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06137|KX-01 SRC common genes SRC common pathways GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0098609| SRC GO:0060491| regulation of cell projection assembly SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0036120| SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0030168| platelet activation SRC;LYN GO:0043149| stress fiber assembly SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0071456| cellular response to hypoxia SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process LYN;HCK;SRC GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1 GO:2000386| positive regulation of ovarian follicle development SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1 GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway SRC;BCR;ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;SRC GO:0071398| cellular response to fatty acid SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion ABL1;HCK;SRC GO:0045087| innate immune response LYN;SRC;HCK;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 GO:0042493| response to drug ABCB1;SRC;LYN GO:0038083| LYN;ABL1;HCK;SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration SRC;LYN GO:0016032| viral reproduction LYN;SRC;HCK GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0038096| LYN;ABL1;HCK;SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 6199:[DB06616 DB04271] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction PDE4D;LYN;BCR;SRC;MAP2K1 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;PDE4D GO:0050900| leukocyte migration SRC;PDE4D;LYN 6200:[DB06616 DB11714] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11714|Durvalumab CD274;CD80 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CD274 GO:0031295| T cell costimulation LYN;CD274;CD80;SRC GO:0030335| positive regulation of cell migration LYN;CD274 GO:0016032| viral reproduction CD80;LYN;SRC;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;LYN;SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CD80;MAP3K2;CDK2 GO:0035556| intracellular signal transduction BCR;SRC;CD80;CAMK2G;LYN 6201:[DB06616 DB03753] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;CYP3A4 GO:0006954| inflammatory response HCK;PTGS1;LYN GO:0006979| response to oxidative stress ABL1;PTGS1 6202:[DB06616 DB14025] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;CYP1A2;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C19;CYP2C9;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP1A2;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP1A2;CYP2D6;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP1A2;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042493| response to drug LYN;CYP1A2;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;CYP3A4;CYP2C9;CYP1A2 6203:[DB06616 DB14634] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14634|Fluprednidene acetate CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 6204:[DB06616 DB08455] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08455|Ro 12-7310 CRABP2 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;CRABP2;BCR;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;CRABP2 6205:[DB06616 DB04690] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0016310| phosphorylation TOP1;MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0018105| peptidyl-serine phosphorylation SRC;TOP1;CAMK2G;CDK2 GO:0002576| platelet degranulation ALB;LYN GO:1901529| ABCB1 GO:0006260| DNA replication TOP1;CDK2 GO:0016032| viral reproduction TOP1;LYN;HCK;SRC GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug LYN;TOP1;ABCG2;SRC;ABCB1 6206:[DB06616 DB03499] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03499|Malate Ion fumC;glcB;ME2;CS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;ME2 6207:[DB06616 DB02486] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways 6208:[DB06616 DB06994] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0043542| endothelial cell migration ABL1;DPP4 GO:0007155| cell adhesion DPP4;ABL1;HCK;SRC GO:0008284| positive regulation of cell proliferation HCK;DPP4;LYN;CDK2 6209:[DB06616 DB07604] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07604|(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE ATP2A1 common genes common pathways GO:0006816| calcium ion transport CAMK2G;ATP2A1 6210:[DB06616 DB00154] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation FABP7;PTGS2;LYN;MAP2K1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0007399| nervous system development CAMK2G;FABP7 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0042493| response to drug PTGS2;LYN;ABCB1;SRC 6211:[DB06616 DB00221] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways GO:0007165| signal transduction BCR;ADRB1;SRC;MAP2K1;LYN;ADRB2 GO:0045453| bone resorption ADRB2;SRC GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;ADRB2 6212:[DB06616 DB05227] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05227|APD791 HTR2A common genes common pathways GO:0007165| signal transduction HTR2A;LYN;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;ABL1;MAP2K1;SRC;MAP2K2 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;HTR2A GO:0016032| viral reproduction LYN;HTR2A;HCK;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;ABL1;SRC GO:0042493| response to drug LYN;HTR2A;SRC;ABCB1 6213:[DB06616 DB05104] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05104|Asimadoline OPRK1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;SRC;BCR GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0007165| signal transduction OPRK1;MAP2K1;BCR;SRC;LYN 6214:[DB06616 DB04297] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04297|7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide HDAC8;HDAC7 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent HDAC7;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;HDAC7;CDK2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis HDAC7;ABL1 GO:0006355| regulation of transcription, DNA-dependent HDAC7;ABL1;HDAC8 GO:0010629| negative regulation of gene expression HDAC8;MAP2K2;MAP2K1 6215:[DB06616 DB05013] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways GO:0016572| histone phosphorylation PRKCD;CDK2 GO:0007165| signal transduction SRC;BCR;MAP2K1;PRKCD;LYN GO:0070555| response to interleukin-1 PRKCA;SRC GO:0060333| interferon-gamma-mediated signaling pathway HCK;PRKCD;CAMK2G GO:0032956| regulation of actin cytoskeleton organization PRKCD;ABL1 GO:0006468| protein phosphorylation ABL1;PRKCA;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;PRKCD GO:0030168| platelet activation LYN;PRKCD;PRKCA;SRC GO:0016310| phosphorylation ABL1;PRKCA;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;PRKCD GO:0010595| positive regulation of endothelial cell migration ABL1;PRKCA GO:0030335| positive regulation of cell migration PRKCA;LYN GO:0007411| axon guidance SRC;PRKCA GO:0043407| negative regulation of MAP kinase activity LYN;PRKCD GO:0070301| cellular response to hydrogen peroxide ABL1;PRKCD GO:0007049| cell cycle CDK2;PRKCD;SRC GO:0018107| peptidyl-threonine phosphorylation CAMK2G;PRKCD;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;PRKCA GO:0042100| B cell proliferation ABL1;PRKCD GO:0045785| positive regulation of cell adhesion PRKCA;SRC GO:0006915| apoptotic process PRKCD;ABL1;PRKCA GO:0007155| cell adhesion ABL1;PRKCA;HCK;SRC GO:0018105| peptidyl-serine phosphorylation SRC;PRKCA;PRKCD;CAMK2G;CDK2 GO:0035556| intracellular signal transduction CAMK2G;LYN;PRKCD;PRKCA;BCR;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;PRKCD GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;PRKCD;LYN GO:0045931| positive regulation of mitotic cell cycle ABL1;PRKCA GO:0038128| SRC;PRKCA GO:0038096| LYN;PRKCD;ABL1;HCK;SRC GO:0050728| negative regulation of inflammatory response PRKCD;BCR GO:0090330| regulation of platelet aggregation LYN;PRKCA GO:0090398| cellular senescence MAP2K1;PRKCD 6216:[DB06616 DB04803] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04803|Verdoheme HMOX1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;ABL1 GO:0042542| response to hydrogen peroxide SRC;HMOX1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;HMOX1 GO:0035556| intracellular signal transduction BCR;SRC;HMOX1;CAMK2G;LYN GO:0055114| oxidation-reduction process CYP2C8;HMOX1;CYP3A4 GO:0034605| cellular response to heat LYN;HMOX1 GO:0071456| cellular response to hypoxia SRC;HMOX1 GO:0006979| response to oxidative stress HMOX1;ABL1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;HMOX1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;HMOX1 GO:0006915| apoptotic process ABL1;HMOX1 GO:0008285| negative regulation of cell proliferation HMOX1;LYN;MAP2K1 6217:[DB06616 DB00712] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00712|Flurbiprofen PTGS1;PTGS2;CYP2C9;UGT2B7;UGT1A1;UGT1A3;UGT1A9;UGT2B4;ALB;ABCC4;SLC22A6 common genes common pathways GO:0042493| response to drug LYN;UGT1A1;PTGS2;ABCC4;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;ABCC4;CYP2C8;PTGS2;CYP3A4;CYP2C9 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0032496| response to lipopolysaccharide BCR;UGT1A1;PTGS2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC;PTGS2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0002576| platelet degranulation ABCC4;ALB;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;UGT2B4;UGT1A9;CYP2C8;PTGS1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS2;PTGS1;UGT2B7 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;LYN;ABCC4 GO:0055085| transmembrane transport SLC22A6;ABCB1;ABCC4 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance ABCC4;PTGS2;UGT1A1;CDK2 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT1A1;CYP2C8;UGT2B7 GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;UGT1A3;CYP3A4;CYP2C9;UGT1A9;UGT1A1 GO:0070542| response to fatty acid SRC;PTGS2 6218:[DB06616 DB05706] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;CDK2;LYN;ABL1 GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 6219:[DB06616 DB04487] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04487|N-Methylleucine CXCL10 common genes common pathways GO:0006935| chemotaxis CXCL10;MAP2K1 GO:0008284| positive regulation of cell proliferation HCK;CXCL10;CDK2;LYN GO:0071222| cellular response to lipopolysaccharide CXCL10;ABL1;SRC;BCR GO:0009615| response to virus SRC;CXCL10 GO:0042127| regulation of cell proliferation CXCL10;SRC;ABL1 GO:0032496| response to lipopolysaccharide BCR;CXCL10 GO:0006954| inflammatory response HCK;CXCL10;LYN GO:0007165| signal transduction LYN;CXCL10;SRC;BCR;MAP2K1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;CXCL10 GO:0030335| positive regulation of cell migration CXCL10;LYN GO:0034605| cellular response to heat LYN;CXCL10 6220:[DB06616 DB08167] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08167|Methylthioninium ACHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0007155| cell adhesion HCK;SRC;ABL1;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0006260| DNA replication CDK2;ACHE 6221:[DB06616 DB11584] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11584|Pipradrol DRD1;DRD5 common genes common pathways GO:0010628| positive regulation of gene expression DRD1;MAP2K1;SRC GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0007165| signal transduction LYN;DRD1;SRC;BCR;DRD5;MAP2K1 GO:1903351| DRD1;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0042493| response to drug DRD1;SRC;ABCB1;LYN GO:0001932| regulation of protein phosphorylation MAP2K1;DRD1;LYN 6222:[DB06616 DB08658] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08658|ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0042493| response to drug SRC;ABCB1;BCHE;LYN 6223:[DB06616 DB05492] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05492|Epicept NP-1 OPRM1;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;OPRL1 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;ADRA1A;SRC;MAP2K2;MAP2K1;ABL1;HTR2B;HTR2C GO:0006915| apoptotic process ABL1;ADRA1A GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;ADRA2B;MAP3K2 GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0043406| positive regulation of MAP kinase activity HTR2B;ADRA2A;SRC;HTR2A GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;OPRM1;LYN GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;OPRL1;ABL1;ADRA1B;OPRM1;ADRA1D;HTR2A GO:0030168| platelet activation SRC;ADRA2A;ADRA2C;LYN;ADRA2B GO:0016310| phosphorylation HTR2B;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction SRC;ADRA1A;BCR;OPRL1;MAP2K1;ADRA2A;ADRA1B;HTR2C;HTR2B;ADRA1D;OPRM1;HRH1;ADRA2C;ADRA2B;LYN;HTR2A GO:0050715| positive regulation of cytokine secretion SRC;HTR2B GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0042493| response to drug LYN;HTR2A;SRC;ADRA1A;ABCB1;HTR2C;HTR2B GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;HTR2A GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;HTR2B GO:0016032| viral reproduction LYN;HTR2A;HCK;SRC GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0007275| multicellular organismal development ADRA1D;CDK2;CAMK2G;ADRA1B GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0007507| heart development HTR2B;MAP2K1 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0008284| positive regulation of cell proliferation ADRA1D;HTR2A;LYN;CDK2;HCK;HTR2B;ADRA2A GO:0043066| negative regulation of apoptotic process HTR2B;HCK;SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;ADRA1A;BCR;ADRA1B 6224:[DB06616 DB02498] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02498|Carba-Nicotinamide-Adenine-Dinucleotide PARP1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PARP1 GO:1901216| ABL1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 GO:0006281| DNA repair CDK2;PARP1;ABL1 GO:0006974| response to DNA damage stimulus CDK2;LYN;PARP1;ABL1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0006915| apoptotic process ABL1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;PARP1 GO:1900182| SRC;PARP1 GO:0032869| cellular response to insulin stimulus SRC;PARP1 6225:[DB06616 DB02123] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction LYN;HCK;SLC10A1;SRC GO:0055085| transmembrane transport SLC10A1;SLC10A2;ABCB1;ABCB11;SLCO1A2 GO:0006810| transport ABCB11;ABCB1;SLC10A2;SLC10A1 6226:[DB06616 DB05890] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05890|VEGF-AS VEGFA common genes common pathways GO:0048010| vascular endothelial growth factor receptor signaling pathway VEGFA;SRC GO:0042327| positive regulation of phosphorylation LYN;VEGFA GO:0051272| positive regulation of cellular component movement VEGFA;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;VEGFA GO:0002576| platelet degranulation VEGFA;LYN GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;CDK2 GO:0008360| regulation of cell shape HCK;VEGFA GO:0007399| nervous system development CAMK2G;VEGFA GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA GO:0007498| mesoderm development HCK;VEGFA GO:0007275| multicellular organismal development VEGFA;CDK2;CAMK2G GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;VEGFA;LYN GO:0031954| positive regulation of protein autophosphorylation VEGFA;SRC GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;SRC GO:0001934| positive regulation of protein phosphorylation VEGFA;LYN;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;ABL1 GO:0030335| positive regulation of cell migration LYN;VEGFA GO:0010595| positive regulation of endothelial cell migration ABL1;VEGFA GO:0030154| cell differentiation VEGFA;CAMK2G;HCK GO:0071456| cellular response to hypoxia VEGFA;SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1;VEGFA GO:0043406| positive regulation of MAP kinase activity VEGFA;SRC GO:0045785| positive regulation of cell adhesion SRC;VEGFA GO:0070374| positive regulation of ERK1 and ERK2 cascade VEGFA;ABL1;MAP2K1;MAP2K2;SRC 6227:[DB06616 DB07779] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;LYN;SRC GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;DPP4 GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0043542| endothelial cell migration ABL1;DPP4 6228:[DB06616 DB12328] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12328|Cantharidin AHR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent AHR;MAP3K2;CDK2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent AHR;ABL1 GO:0006805| xenobiotic metabolic process CYP2C8;AHR;CYP3A4 GO:0006915| apoptotic process AHR;ABL1 GO:0009636| response to toxin AHR;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;AHR GO:0007049| cell cycle SRC;CDK2;AHR 6229:[DB06616 DB08043] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes ABL1 common pathways GO:0030036| actin cytoskeleton organization BCR;ABL1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:1902036| ABL1 GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 GO:0038096| HCK;SRC;ABL1;LYN GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1 GO:0006298| mismatch repair ABL1 GO:0042770| signal transduction in response to DNA damage ABL1 GO:0050885| neuromuscular process controlling balance ABL1;BCR GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1 GO:0006914| autophagy ABL1 GO:0000278| mitotic cell cycle ABL1 GO:1900042| ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:0038083| LYN;SRC;HCK;ABL1 GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:1901216| ABL1 GO:1904531| ABL1 GO:0010506| regulation of autophagy ABL1 GO:0006909| phagocytosis ABL1;HCK GO:2000772| regulation of cellular senescence ABL1 GO:0048668| collateral sprouting ABL1 GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2 GO:0051882| mitochondrial depolarization ABL1 GO:0006281| DNA repair CDK2;ABL1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:1904528| ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030155| regulation of cell adhesion ABL1 GO:0030035| microspike assembly ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:1900275| ABL1 GO:2000145| regulation of cell motility ABL1 GO:0006897| endocytosis ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0043542| endothelial cell migration ABL1 GO:1905244| ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0030516| regulation of axon extension ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0038189| ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0006464| protein modification process ABL1 GO:0046632| alpha-beta T cell differentiation ABL1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;CAMK2G;LYN GO:0050853| B cell receptor signaling pathway LYN;ABL1 GO:0001922| B-1 B cell homeostasis ABL1 GO:1900272| ABL1 GO:1990051| ABL1 GO:0009791| post-embryonic development ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0045184| establishment of protein localization ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0042100| B cell proliferation ABL1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0045580| regulation of T cell differentiation ABL1 GO:0002322| B cell proliferation involved in immune response ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0006915| apoptotic process ABL1 GO:0030182| neuron differentiation MAP2K1;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1 GO:1902715| ABL1 GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:1905555| ABL1 GO:1903351| ABL1 GO:0090135| actin filament branching ABL1 GO:0048538| thymus development MAP2K1;ABL1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0048536| spleen development ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:0006979| response to oxidative stress ABL1 GO:1900026| ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0001843| neural tube closure ABL1 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0016310| phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0030100| regulation of endocytosis ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:1903053| ABL1 GO:0072358| cardiovascular system development ABL1 6230:[DB06616 DB00817] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 6231:[DB06616 DB07623] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2A6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP2C8;CYP2A6;CYP3A4 6232:[DB06616 DB07524] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07524|N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine PIM1 common genes common pathways GO:0007275| multicellular organismal development PIM1;CAMK2G;CDK2 GO:0043066| negative regulation of apoptotic process PIM1;HCK;SRC GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2;PIM1 GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;PIM1;MAP3K2 GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;PIM1;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0008283| cell proliferation SRC;PIM1 GO:0006915| apoptotic process ABL1;PIM1 GO:0046777| protein autophosphorylation ABL1;HCK;BCR;SRC;LYN;CAMK2G;PIM1 GO:0007049| cell cycle SRC;CDK2;PIM1 6233:[DB06616 DB07248] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways GO:0006468| protein phosphorylation MAP3K2;PTK2;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1;PTK2 GO:0030335| positive regulation of cell migration PTK2;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;PTK2;SRC GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;PTK2;CDK2;LYN GO:0007172| signal complex assembly SRC;PTK2 GO:0022408| negative regulation of cell-cell adhesion PTK2;ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway PTK2;SRC GO:0033628| regulation of cell adhesion mediated by integrin PTK2;LYN GO:0048013| ephrin receptor signaling pathway SRC;LYN;PTK2 GO:0007411| axon guidance PTK2;SRC GO:0046777| protein autophosphorylation CAMK2G;PTK2;LYN;ABL1;SRC;BCR;HCK GO:0043542| endothelial cell migration PTK2;ABL1 GO:0007275| multicellular organismal development CDK2;PTK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;LYN;PTK2 GO:0048870| cell motility PTK2;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;PTK2 GO:0001932| regulation of protein phosphorylation MAP2K1;PTK2;LYN GO:0008360| regulation of cell shape PTK2;HCK GO:0045087| innate immune response ABL1;SRC;HCK;PTK2;LYN GO:0043066| negative regulation of apoptotic process PTK2;HCK;SRC GO:0071560| cellular response to transforming growth factor beta stimulus PTK2;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway PTK2;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTK2;HCK GO:0001934| positive regulation of protein phosphorylation PTK2;LYN;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;PTK2 GO:0038083| LYN;PTK2;ABL1;SRC;HCK GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;PTK2 GO:0051897| positive regulation of protein kinase B signaling cascade PTK2;SRC GO:0038096| ABL1;HCK;SRC;LYN;PTK2 GO:0010632| regulation of epithelial cell migration PTK2;SRC GO:2000811| negative regulation of anoikis SRC;PTK2 6234:[DB06616 DB00900] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0008283| cell proliferation SRC;SLC29A2 GO:0071456| cellular response to hypoxia SRC;SLC29A1 GO:0042493| response to drug SRC;ABCB1;LYN;PNP GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB 6235:[DB06616 DB03951] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 6236:[DB06616 DB05319] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05319|Oportuzumab monatox EPCAM common genes common pathways GO:0008284| positive regulation of cell proliferation EPCAM;HCK;LYN;CDK2 GO:0050900| leukocyte migration SRC;EPCAM;LYN GO:0098609| EPCAM;SRC 6237:[DB06616 DB07254] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07254|N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL]AMINO]PHENYL]METHANESULFONAMIDE EPHB4 common genes common pathways GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;EPHB4;LYN GO:0016310| phosphorylation CAMK2G;LYN;CDK2;EPHB4;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;EPHB4;CDK2;LYN;MAP3K2 GO:0046777| protein autophosphorylation ABL1;SRC;BCR;HCK;CAMK2G;EPHB4;LYN GO:0048013| ephrin receptor signaling pathway EPHB4;LYN;SRC GO:0007155| cell adhesion ABL1;HCK;SRC;EPHB4 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;LYN;EPHB4 GO:0007275| multicellular organismal development CAMK2G;CDK2;EPHB4 6238:[DB06616 DB09076] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction CHRM5;CHRM3;CHRM1;CHRM2;LYN;SRC;BCR;CHRM4;MAP2K1 GO:0008283| cell proliferation SRC;CHRM4;CHRM5;CHRM3;CHRM1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0009615| response to virus SRC;CHRM2 GO:0008284| positive regulation of cell proliferation CHRM1;LYN;CDK2;HCK GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1;CHRM2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0042493| response to drug ABCB1;SRC;LYN GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 6239:[DB06616 DB08804] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0007165| signal transduction LYN;AR;BCR;SRC;MAP2K1 GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0009636| response to toxin LYN;MAOB GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0008284| positive regulation of cell proliferation HCK;AR;LYN;CDK2 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0060065| uterus development SRC;CYP19A1 GO:0051259| protein oligomerization CAMK2G;AR GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process MAOB;MAOA;CYP19A1;CYP3A4;CYP2C8 GO:0042493| response to drug MAOB;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;AR;MAP3K2;CDK2 6240:[DB06616 DB08516] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08516|(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] MAOB common genes common pathways GO:0009636| response to toxin MAOB;LYN GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0055114| oxidation-reduction process CYP2C8;MAOB;CYP3A4 GO:0042493| response to drug ABCB1;SRC;MAOB;LYN 6241:[DB06616 DB00665] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes CYP2C8 common pathways GO:0010628| positive regulation of gene expression AR;MAP2K1;SRC GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0071375| cellular response to peptide hormone stimulus SRC;POR GO:0002933| CYP3A4;CYP2C8 GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19 GO:0097267| CYP2C8;CYP2C19 GO:0007165| signal transduction AR;BCR;SRC;MAP2K1;LYN GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A4 GO:0006810| transport ABCB1;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;AR;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1;POR GO:0055114| oxidation-reduction process POR;CYP2C19;CYP2C8;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process POR;SRC GO:0042327| positive regulation of phosphorylation AR;LYN GO:0043066| negative regulation of apoptotic process POR;SRC;HCK GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C19;CYP2C8;POR GO:0008284| positive regulation of cell proliferation CDK2;LYN;AR;HCK GO:0006082| organic acid metabolic process CYP2C8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0051259| protein oligomerization AR;CAMK2G 6242:[DB06616 DB01342] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01342|Forasartan AGTR1 common genes common pathways GO:0050727| regulation of inflammatory response LYN;AGTR1;HCK GO:0042127| regulation of cell proliferation SRC;AGTR1;ABL1 GO:0007165| signal transduction MAP2K1;BCR;SRC;AGTR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ABL1 6243:[DB06616 DB05049] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05049|DDP733 HTR3A common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;HTR3A;LYN 6244:[DB06616 DB03553] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03553|Glutaric Acid ilvE;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;SLC22A7;SLC22A11;ABCB1 GO:0009636| response to toxin LYN;SLC22A8 6245:[DB06616 DB00605] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0060440| trachea formation MAPK3;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARD;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0038083| LYN;MAPK3;ABL1;SRC;HCK GO:0042493| response to drug CYP1A1;LYN;PTGS2;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent PPARD;ABL1 GO:0060425| lung morphogenesis MAP2K1;MAPK3 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0001934| positive regulation of protein phosphorylation LYN;MAPK3;ABL1 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;AKR1B1;CYP3A4;CYP1A1;AKR1B10;PTGS2 GO:0016032| viral reproduction MAPK3;LYN;SRC;HCK GO:0070371| ERK1 and ERK2 cascade MAPK3;MAP2K1;MAP2K2 GO:0060324| face development MAPK3;MAP2K1 GO:0050728| negative regulation of inflammatory response BCR;PPARD GO:0006954| inflammatory response PTGS2;LYN;HCK;PTGS1 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;MAPK3;CAMK2G GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0038096| LYN;MAPK3;ABL1;HCK;SRC GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1;MAPK3 GO:2000641| regulation of early endosome to late endosome transport MAPK3;MAP2K1;SRC;MAP2K2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1;PPARD;PTGS2 GO:0032496| response to lipopolysaccharide BCR;CYP1A1;PTGS2;MAPK3 GO:0006975| DNA damage induced protein phosphorylation ABL1;MAPK3 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0035556| intracellular signal transduction SRC;BCR;LYN;CAMK2G;MAPK3 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2;PPARD;ALB;SRC;HCK GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;MAPK3;HCK GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0002576| platelet degranulation LYN;ALB GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0009615| response to virus CYP1A1;SRC GO:0018105| peptidyl-serine phosphorylation MAPK3;CDK2;CAMK2G;SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;PPARD GO:0006935| chemotaxis MAP2K1;PTGDR2 GO:0008284| positive regulation of cell proliferation HCK;PTGS2;PPARD;CDK2;LYN GO:0006629| lipid metabolic process PTGS1;PPARD;PTGS2;CYP3A4 GO:0006974| response to DNA damage stimulus MAPK3;CDK2;LYN;ABL1 GO:0071260| cellular response to mechanical stimulus MAPK3;PTGS2;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;CDK2 GO:0007507| heart development PPARD;MAP2K1 GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A1;LYN;PTGS2 GO:0009636| response to toxin LYN;CYP1A1;MAPK3 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;MAPK3 GO:0038095| LYN;MAPK3 GO:0008283| cell proliferation PPARD;CYP1A1;SRC GO:0032872| regulation of stress-activated MAPK cascade MAPK3;MAP2K2;MAP2K1 GO:0006915| apoptotic process PPARD;MAPK3;ABL1 GO:0000187| activation of MAPK activity MAPK3;MAP3K2;MAP2K2;MAP2K1 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAPK3;ABL1;SRC;MAP2K2;MAP2K1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;SRC;PPARD;MAPK3 GO:0034614| cellular response to reactive oxygen species SRC;MAPK3 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0010033| response to organic substance CDK2;CYP1A1;AKR1B1;PPARD;PTGS2 GO:0007049| cell cycle SRC;CDK2;MAPK3 GO:0045892| negative regulation of transcription, DNA-dependent PPARD;SRC GO:0090170| regulation of Golgi inheritance MAP2K1;MAP2K2;MAPK3 GO:0007411| axon guidance SRC;MAPK3 GO:0008202| steroid metabolic process CYP1A1;CYP3A4;AKR1B10;CYP2C8 GO:0034605| cellular response to heat PTGS2;LYN GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAPK3;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0030168| platelet activation MAPK3;LYN;SRC GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;MAPK3;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0030154| cell differentiation PPARD;CAMK2G;HCK GO:0071456| cellular response to hypoxia SRC;PTGS2;PPARD GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:1900034| MAPK3;CAMK2G GO:0030878| thyroid gland development MAPK3;MAP2K1 GO:0048538| thymus development MAPK3;ABL1;MAP2K1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity MAPK3;HCK GO:1903351| MAPK3;ABL1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A1 GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;PTGDR2 6246:[DB06616 DB03796] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes CYP2C8 common pathways GO:0007275| multicellular organismal development CAMK2G;PAEP;CDK2 GO:0006082| organic acid metabolic process CYP2C8 GO:0007399| nervous system development CAMK2G;PPT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;CDK2 GO:0007507| heart development PPARA;MAP2K1 GO:0006629| lipid metabolic process PPARA;CYP3A4;FABP5 GO:0050727| regulation of inflammatory response FABP4;HCK;LYN GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB;PPT1 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent PPARA;HNF4G;SEC14L2;ABL1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug SRC;ABCB1;FABP3;LYN GO:0045893| positive regulation of transcription, DNA-dependent SEC14L2;MAP2K2;SRC;MAP2K1;PPARA;CDK2;MAP3K2 GO:0050728| negative regulation of inflammatory response BCR;PPARA GO:0006468| protein phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;RHO;LYN;CDK2;CAMK2G GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0097267| CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0007420| brain development BCR;PPT1 GO:0007165| signal transduction MAP2K1;BCR;SRC;LALBA;RHO;LYN GO:0070542| response to fatty acid FABP3;SRC GO:0065009| regulation of molecular function CAMK2G;TRAPPC3 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0032868| response to insulin stimulus FABP3;PPARA;LYN GO:0006915| apoptotic process ABL1;PAEP;LALBA GO:0002933| CYP3A4;CYP2C8 GO:0045892| negative regulation of transcription, DNA-dependent SRC;FABP4 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;FABP3 6247:[DB06616 DB07847] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07847|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE F10 common genes common pathways GO:0007596| blood coagulation LYN;F10 GO:0030335| positive regulation of cell migration LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 6248:[DB06616 DB05187] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0032868| response to insulin stimulus PPARA;LYN GO:0006915| apoptotic process PPARD;ABL1 GO:0008283| cell proliferation PPARD;SRC GO:0014070| response to organic cyclic compound PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARD;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0010033| response to organic substance PPARD;PPARG;CDK2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;PPARD GO:0071456| cellular response to hypoxia SRC;PPARD GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0030154| cell differentiation HCK;PPARD;CAMK2G GO:0007165| signal transduction LYN;PPARG;MAP2K1;SRC;BCR GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARD;PPARG;PPARA GO:0042493| response to drug ABCB1;SRC;LYN;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;PPARA;PPARG;MAP3K2;PPARD GO:0050728| negative regulation of inflammatory response BCR;PPARA;PPARD GO:0042127| regulation of cell proliferation SRC;ABL1;PPARD GO:0045087| innate immune response PPARG;LYN;ABL1;SRC;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG;PPARA;PPARD GO:0007507| heart development MAP2K1;PPARD;PPARA;PPARG GO:0006629| lipid metabolic process PPARD;PPARA;CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0071222| cellular response to lipopolysaccharide PPARD;ABL1;BCR;SRC GO:0008284| positive regulation of cell proliferation PPARD;LYN;CDK2;HCK GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043066| negative regulation of apoptotic process PPARD;HCK;SRC GO:0071300| cellular response to retinoic acid LYN;PPARG 6249:[DB06616 DB05838] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05838|OPC-51803 AVPR2 common genes common pathways GO:0007165| signal transduction LYN;AVPR2;MAP2K1;BCR;SRC GO:0010628| positive regulation of gene expression AVPR2;MAP2K1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;AVPR2;HCK 6250:[DB06616 DB03107] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 6251:[DB06616 DB07026] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07026|(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE MMP12 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;MMP12 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;MMP12 6252:[DB06616 DB03729] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03729|2-Amino-5-Hydroxy-Benzimidazole PLAU common genes common pathways GO:0006935| chemotaxis MAP2K1;PLAU GO:0042127| regulation of cell proliferation PLAU;ABL1;SRC GO:0007596| blood coagulation LYN;PLAU GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007165| signal transduction BCR;SRC;MAP2K1;PLAU;LYN GO:0030335| positive regulation of cell migration LYN;PLAU 6253:[DB06616 DB04454] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways GO:0002576| platelet degranulation LYN;EGF GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;EGF GO:2000145| regulation of cell motility ABL1;EGF GO:0042327| positive regulation of phosphorylation LYN;EGF GO:0007275| multicellular organismal development GATM;CAMK2G;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation LYN;EGF;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0070371| ERK1 and ERK2 cascade EGF;MAP2K1;MAP2K2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;EGF;LYN GO:0038128| EGF;SRC GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;EGF GO:0006260| DNA replication EGF;CDK2 GO:0051897| positive regulation of protein kinase B signaling cascade EGF;SRC GO:0007173| epidermal growth factor receptor signaling pathway EGF;SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;EGF GO:0007165| signal transduction BCR;SRC;MAP2K1;EGF;LYN GO:0030335| positive regulation of cell migration LYN;EGF GO:0000186| activation of MAPKK activity EGF;MAP3K2 GO:0010628| positive regulation of gene expression SRC;MAP2K1;EGF GO:0043406| positive regulation of MAP kinase activity SRC;EGF GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;EGF 6254:[DB06616 DB02705] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02705|6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0030335| positive regulation of cell migration PLAU;LYN GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;PLAU GO:0007596| blood coagulation PLAU;LYN GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0042127| regulation of cell proliferation PLAU;ABL1;SRC GO:0006935| chemotaxis MAP2K1;PLAU 6255:[DB06616 DB04775] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04775|Reidispongiolide C ACTA1 common genes common pathways GO:0010628| positive regulation of gene expression SRC;ACTA1;MAP2K1 GO:0009612| response to mechanical stimulus SRC;ACTA1 6256:[DB06616 DB06080] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0010629| negative regulation of gene expression MAP2K1;KDR;MAP2K2 GO:0038083| LYN;ABL1;SRC;KDR;HCK GO:0001934| positive regulation of protein phosphorylation ABL1;CSF1R;KDR;FLT4;LYN GO:0016032| viral reproduction HCK;KDR;SRC;LYN GO:0006954| inflammatory response HCK;KIT;CSF1R;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0030218| erythrocyte differentiation LYN;KIT GO:0051897| positive regulation of protein kinase B signaling cascade SRC;KIT GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;KIT;MAP2K1 GO:0019221| cytokine-mediated signaling pathway KIT;CSF1R;HCK;FLT3 GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0042127| regulation of cell proliferation SRC;KIT;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein CSF1R;KIT;FLT3;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;CSF1R;KIT;KDR;HCK;MAP2K2;BCR;SRC;LYN;FLT3;FLT4;FLT1 GO:0007275| multicellular organismal development CAMK2G;CDK2;FLT1;CSF1R;KDR GO:0043066| negative regulation of apoptotic process HCK;KDR;CSF1R;SRC;FLT4 GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC;FLT4;FLT1 GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR;KIT GO:2000249| regulation of actin cytoskeleton reorganization CSF1R;ABL1 GO:0008284| positive regulation of cell proliferation FLT4;FLT3;CDK2;LYN;FLT1;HCK;KDR;CSF1R;KIT GO:0006935| chemotaxis FLT1;MAP2K1 GO:0045124| regulation of bone resorption SRC;CSF1R GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;FLT3;MAP3K2 GO:0008360| regulation of cell shape KDR;CSF1R;KIT;HCK GO:0045087| innate immune response CSF1R;HCK;SRC;ABL1;LYN GO:0016477| cell migration SRC;FLT1 GO:0008283| cell proliferation SRC;CSF1R GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;KIT;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;CSF1R;KDR;SRC;MAP2K2;ABL1;FLT4 GO:0010628| positive regulation of gene expression SRC;KIT;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1;CSF1R GO:0046777| protein autophosphorylation SRC;BCR;HCK;KDR;KIT;CSF1R;ABL1;FLT1;CAMK2G;FLT4;FLT3;LYN GO:0097028| dendritic cell differentiation LYN;FLT3 GO:0008285| negative regulation of cell proliferation CSF1R;MAP2K1;LYN GO:0007411| axon guidance CSF1R;SRC GO:0043406| positive regulation of MAP kinase activity SRC;KIT;FLT1;FLT3 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT1;LYN;FLT4;FLT3;KDR;CSF1R;KIT;HCK GO:0030335| positive regulation of cell migration KDR;CSF1R;KIT;FLT1;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;KIT;LYN;FLT3;FLT1 GO:0016310| phosphorylation LYN;CDK2;FLT4;FLT3;CAMK2G;MAP3K2;FLT1;ABL1;KDR;KIT;CSF1R;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0010595| positive regulation of endothelial cell migration KDR;ABL1;FLT4 GO:0030154| cell differentiation KDR;HCK;FLT3;CAMK2G;FLT1 GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;KIT;MAP2K1;CSF1R;KDR;CAMK2G;FLT3;FLT4;CDK2;LYN;FLT1;MAP3K2 GO:0002376| immune system process LYN;SRC;CSF1R;HCK GO:0030097| hemopoiesis CSF1R;KIT;FLT3;LYN GO:0007165| signal transduction LYN;KIT;MAP2K1;CSF1R;BCR;SRC 6257:[DB06616 DB00651] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;BCR;PDE7A;PDE7B;PDE4C;PDE4B;PDE4D;PDE4A;ADORA2A;LYN;ADORA1 GO:0007417| central nervous system development SRC;ADORA2A;LYN GO:0000186| activation of MAPKK activity ADORA1;MAP3K2 GO:0008285| negative regulation of cell proliferation ADORA1;LYN;ADORA2A;MAP2K1 GO:0007596| blood coagulation ADORA2A;LYN GO:0006915| apoptotic process ADORA2A;ABL1 GO:0043066| negative regulation of apoptotic process ADORA1;SRC;HCK GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PDE4B;PDE4D GO:0007399| nervous system development CAMK2G;ADORA1 GO:0050728| negative regulation of inflammatory response BCR;ADORA2A;ADORA1 GO:0006954| inflammatory response HCK;ADORA2A;LYN;ADORA1 GO:0051924| regulation of calcium ion transport ADORA2A;CAMK2G GO:0006909| phagocytosis ADORA2A;ADORA1;ABL1;HCK GO:0042493| response to drug ADORA2A;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;ADORA2A GO:0050900| leukocyte migration PDE4D;LYN;SRC;PDE4B 6258:[DB06616 DB06230] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;OPRD1 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0006629| lipid metabolic process UGT2B7;CYP3A4 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;BCR;SRC GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;OPRM1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0008202| steroid metabolic process UGT1A8;CYP3A4;UGT2B7;CYP2C8 GO:0017144| drug metabolic process UGT1A3;CYP2C8;UGT1A8;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;BCR;OPRK1;OPRD1;OPRM1;LYN 6259:[DB06616 DB06642] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06642|Bevasiranib VEGFA common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;VEGFA GO:0010628| positive regulation of gene expression VEGFA;MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;VEGFA GO:0045785| positive regulation of cell adhesion SRC;VEGFA GO:0071456| cellular response to hypoxia SRC;VEGFA GO:0030154| cell differentiation HCK;VEGFA;CAMK2G GO:0010595| positive regulation of endothelial cell migration ABL1;VEGFA GO:0030335| positive regulation of cell migration LYN;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;VEGFA GO:0031954| positive regulation of protein autophosphorylation SRC;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;VEGFA;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;VEGFA GO:0010629| negative regulation of gene expression VEGFA;MAP2K1;MAP2K2 GO:0007399| nervous system development VEGFA;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VEGFA GO:0008360| regulation of cell shape HCK;VEGFA GO:0008284| positive regulation of cell proliferation CDK2;LYN;VEGFA;HCK GO:0002576| platelet degranulation LYN;VEGFA GO:0048010| vascular endothelial growth factor receptor signaling pathway VEGFA;SRC GO:0043066| negative regulation of apoptotic process VEGFA;HCK;SRC GO:0051272| positive regulation of cellular component movement LYN;VEGFA GO:0042327| positive regulation of phosphorylation LYN;VEGFA GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein VEGFA;LYN GO:0007498| mesoderm development HCK;VEGFA GO:0007275| multicellular organismal development VEGFA;CDK2;CAMK2G GO:0051894| positive regulation of focal adhesion assembly ABL1;VEGFA 6260:[DB06616 DB11182] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways GO:0045087| innate immune response LYN;SRC;HCK;ABL1;LTF GO:0002576| platelet degranulation LYN;TF;ALB GO:0043066| negative regulation of apoptotic process ALB;LTF;SRC;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;ABL1 GO:0001817| regulation of cytokine production LYN;LTF GO:0006954| inflammatory response LYN;HCK;LYZ GO:0006355| regulation of transcription, DNA-dependent LTF;ABL1 GO:0002376| immune system process LYN;HCK;SRC;LTF GO:0071902| positive regulation of protein serine/threonine kinase activity LTF;MAP2K1;MAP2K2;SRC GO:0033690| positive regulation of osteoblast proliferation LTF;ABL1 6261:[DB06616 DB08708] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08708|N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine PIM1 common genes common pathways GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;HCK;SRC GO:0007275| multicellular organismal development CAMK2G;CDK2;PIM1 GO:0007049| cell cycle CDK2;PIM1;SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;PIM1;ABL1;HCK;SRC;BCR GO:0006915| apoptotic process PIM1;ABL1 GO:0008283| cell proliferation SRC;PIM1 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;PIM1;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;PIM1;MAP3K2;CAMK2G;CDK2;LYN 6262:[DB06616 DB07482] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation CDK2;LYN;DPP4;HCK GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0043542| endothelial cell migration DPP4;ABL1 GO:0031295| T cell costimulation SRC;LYN;DPP4 6263:[DB06616 DB03940] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03940|Oxamic Acid LDHA;LDHB;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A3;ABCB1 GO:0014070| response to organic cyclic compound LYN;LDHA GO:0042542| response to hydrogen peroxide SRC;LDHA GO:0043065| positive regulation of apoptotic process LDHA;SRC;ABL1 GO:0055114| oxidation-reduction process CYP3A4;LDHA;CYP2C8;LDHB GO:0050900| leukocyte migration LYN;SLC16A3;SRC GO:0042493| response to drug ABCB1;SRC;LYN;LDHA 6264:[DB06616 DB04770] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;PDXK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0008283| cell proliferation PDXK;SRC 6265:[DB06616 DB06709] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06709|Methacholine CHRM3 common genes common pathways GO:0007399| nervous system development CHRM3;CAMK2G GO:0007165| signal transduction LYN;CHRM3;SRC;BCR;MAP2K1 GO:0006464| protein modification process CHRM3;ABL1 GO:0008283| cell proliferation CHRM3;SRC 6266:[DB06616 DB02532] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02532|2,4,6-Triaminoquinazoline DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHRS4L1;CYP3A4 6267:[DB06616 DB08339] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes ABL1 common pathways GO:0006974| response to DNA damage stimulus CDK2;LYN;ABL1 GO:0051882| mitochondrial depolarization ABL1 GO:0006281| DNA repair CDK2;ABL1 GO:2000772| regulation of cellular senescence ABL1 GO:0048668| collateral sprouting ABL1 GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0045087| innate immune response LYN;ABL1;HCK;SRC GO:0030155| regulation of cell adhesion ABL1 GO:0030035| microspike assembly ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:1900275| ABL1 GO:2000145| regulation of cell motility ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:0006897| endocytosis ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:1904528| ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN GO:0043542| endothelial cell migration ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0038189| ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:1905244| ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0030516| regulation of axon extension ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0030036| actin cytoskeleton organization BCR;ABL1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:1902036| ABL1 GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 GO:0038096| SRC;HCK;ABL1;LYN GO:0042770| signal transduction in response to DNA damage ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1 GO:0006298| mismatch repair ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1 GO:0006914| autophagy ABL1 GO:0000278| mitotic cell cycle ABL1 GO:0050885| neuromuscular process controlling balance BCR;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:1901216| ABL1 GO:1904531| ABL1 GO:0010506| regulation of autophagy ABL1 GO:0006909| phagocytosis ABL1;HCK GO:1900042| ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:0038083| ABL1;SRC;HCK;LYN GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0007050| cell cycle arrest MAP2K1;ABL1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:1905555| ABL1 GO:0090135| actin filament branching ABL1 GO:1903351| ABL1 GO:1902715| ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:0006979| response to oxidative stress ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:1900026| ABL1 GO:0048538| thymus development MAP2K1;ABL1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0048536| spleen development ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0001843| neural tube closure ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0072358| cardiovascular system development ABL1 GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0030100| regulation of endocytosis ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:1903053| ABL1 GO:0006464| protein modification process ABL1 GO:0046632| alpha-beta T cell differentiation ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;CAMK2G;LYN GO:0050853| B cell receptor signaling pathway ABL1;LYN GO:0001922| B-1 B cell homeostasis ABL1 GO:1900272| ABL1 GO:1990051| ABL1 GO:0009791| post-embryonic development ABL1 GO:0045580| regulation of T cell differentiation ABL1 GO:0002322| B cell proliferation involved in immune response ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0006915| apoptotic process ABL1 GO:0045184| establishment of protein localization ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1 GO:0042100| B cell proliferation ABL1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1 GO:0030182| neuron differentiation ABL1;MAP2K1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 6268:[DB06616 DB05362] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05362|SSR-126517E F10 common genes common pathways GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 6269:[DB06616 DB05069] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways GO:0006816| calcium ion transport CAMK2G;CHRNA9;CHRNA10 GO:0042127| regulation of cell proliferation ABL1;CHRNA10;SRC GO:0042472| inner ear morphogenesis CHRNA10;BCR;CHRNA9 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CHRNA10;CHRNA9 GO:0007165| signal transduction CHRNA9;LYN;BCR;SRC;CHRNA10;MAP2K1 6270:[DB06616 DB02243] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02243|4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide CTSF common genes common pathways 6271:[DB06616 DB14007] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14007|Pentetic acid SERPINA1 common genes common pathways GO:0007596| blood coagulation SERPINA1;LYN GO:0002576| platelet degranulation LYN;SERPINA1 6272:[DB06616 DB08526] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08526|CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE CTSH common genes common pathways GO:0002250| adaptive immune response CTSH;LYN GO:0070371| ERK1 and ERK2 cascade CTSH;MAP2K1;MAP2K2 GO:0010634| positive regulation of epithelial cell migration SRC;CTSH GO:0043066| negative regulation of apoptotic process CTSH;SRC;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;CTSH;HCK GO:0010628| positive regulation of gene expression MAP2K1;SRC;CTSH GO:0006915| apoptotic process CTSH;ABL1 GO:0031648| protein destabilization CTSH;SRC GO:0030335| positive regulation of cell migration LYN;CTSH 6273:[DB06616 DB06229] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways GO:0042493| response to drug HTR2C;HTR2B;SRC;DRD2;ADRA1A;ABCB1;LYN;HTR2A GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0006954| inflammatory response HCK;LYN;HRH1 GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;HTR2B GO:0016032| viral reproduction HCK;SRC;HTR2A;LYN GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;ABL1;SRC GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0048678| response to axon injury LYN;DRD2 GO:0007275| multicellular organismal development ADRA1D;CDK2;CAMK2G;ADRA1B GO:0008284| positive regulation of cell proliferation HTR2A;LYN;CDK2;ADRA1D;HTR2B;ADRA2A;HCK GO:0043066| negative regulation of apoptotic process HCK;SRC;HTR2B GO:0035556| intracellular signal transduction BCR;ADRA1A;SRC;DRD2;ADRA1B;CAMK2G;LYN GO:0007507| heart development MAP2K1;HTR2B GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;ADRA2A;SRC GO:0008283| cell proliferation ADRA1B;SRC;ADRA1D GO:0009636| response to toxin LYN;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K1;MAP2K2;ADRA1A;SRC;DRD2;HTR2B;HTR2C;ABL1 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;ADRA2B;MAP3K2 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;ADRA2A;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;ADRA1A;LYN GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;HTR2B;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ABL1;ADRA1B;ADRA1D;HTR2A GO:0030168| platelet activation ADRA2B;LYN;ADRA2C;ADRA2A;SRC GO:0050715| positive regulation of cytokine secretion HTR2B;SRC GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction MAP2K1;BCR;DRD2;SRC;ADRA1A;ADRA1B;HTR2C;HTR2B;ADRA2A;HRH1;ADRA1D;LYN;ADRA2B;HTR2A;ADRA2C GO:0030900| forebrain development SRC;DRD2 6274:[DB06616 DB04018] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04018|S-Isopropyl-Isothiourea NOS3 common genes common pathways GO:0043542| endothelial cell migration ABL1;NOS3 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;NOS3;HCK GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;LYN 6275:[DB06616 DB02551] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02551|6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0006935| chemotaxis MAP2K1;PLAU GO:0042127| regulation of cell proliferation SRC;PLAU;ABL1 GO:0007165| signal transduction LYN;PLAU;SRC;BCR;MAP2K1 GO:0030335| positive regulation of cell migration PLAU;LYN GO:0007596| blood coagulation PLAU;LYN GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN 6276:[DB06616 DB05630] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05630|Sodium stibogluconate TOP1 common genes common pathways GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;TOP1;MAP3K2;CAMK2G;LYN;CDK2 GO:0016032| viral reproduction SRC;HCK;TOP1;LYN GO:0006260| DNA replication TOP1;CDK2 GO:0042493| response to drug TOP1;LYN;SRC;ABCB1 GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;TOP1;SRC 6277:[DB06616 DB02527] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0010033| response to organic substance ABCC4;CDK2 GO:0007596| blood coagulation LYN;PRKAR1A;PRKAR2B GO:0009636| response to toxin SLC22A8;LYN GO:0014070| response to organic cyclic compound LYN;ABCC4 GO:0000086| G2/M transition of mitotic cell cycle CDK2;PRKAR2B;ABCB1 GO:0055085| transmembrane transport ABCC4;ABCC11;ABCB1;ABCC5;SLC22A7;SLC22A6;SLC22A8;HCN2 GO:0006813| potassium ion transport HCN2;CDK2 GO:0006810| transport ABCC5;ABCB1 GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;PRKAR2B GO:0042493| response to drug LYN;SRC;ABCB1;ABCC4 GO:0055114| oxidation-reduction process ABCC4;CYP2C8;CYP3A4 GO:0002576| platelet degranulation LYN;ABCC4 GO:0035556| intracellular signal transduction SRC;PRKAR2B;BCR;CAMK2G;LYN;PRKAR1A GO:0007507| heart development MAP2K1;PRKAR1A GO:0001932| regulation of protein phosphorylation LYN;PRKAR1A;MAP2K1;PRKAR2B 6278:[DB06616 DB03536] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03536|Benzoyl-Arginine-Alanine-Methyl Ketone CTSF common genes common pathways 6279:[DB06616 DB07954] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PDE8A GO:0001934| positive regulation of protein phosphorylation ABL1;PDE8A;LYN GO:0050900| leukocyte migration SRC;LYN;PDE4D GO:0071560| cellular response to transforming growth factor beta stimulus PDE2A;SRC GO:0071222| cellular response to lipopolysaccharide PDE4D;BCR;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PDE2A GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;CDK2 GO:0043406| positive regulation of MAP kinase activity PDE5A;SRC GO:0000187| activation of MAPK activity MAP3K2;PDE6G;MAP2K2;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade PDE8A;ABL1;MAP2K1;SRC;MAP2K2 GO:0007165| signal transduction PDE9A;PDE7A;SRC;BCR;PDE3B;MAP2K1;LYN;PDE8A;PDE5A;PDE4D;PDE2A GO:0032869| cellular response to insulin stimulus SRC;PDE3B 6280:[DB06616 DB05168] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways GO:0048678| response to axon injury LYN;FOLR1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;FOLR2 GO:0006954| inflammatory response HCK;LYN;FOLR2 6281:[DB06616 DB00984] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;AR;LYN GO:0006810| transport AR;ABCB1 GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0008284| positive regulation of cell proliferation CDK2;LYN;AR;HCK GO:0060065| uterus development SRC;CYP19A1 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0051259| protein oligomerization AR;CAMK2G GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP2C8;CYP19A1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent AR;MAP2K1;MAP2K2;SRC;CDK2;MAP3K2 6282:[DB06616 DB11605] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade NR1H4;ABL1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PPARA GO:0045087| innate immune response NR1H4;LYN;SRC;HCK;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARA;NR1H4 GO:0007507| heart development MAP2K1;PPARA GO:0043066| negative regulation of apoptotic process HCK;SRC;NR1H4 GO:0071398| cellular response to fatty acid NR1H4;SRC GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;NR1I2;CYP3A5;CYP2C8 GO:0071222| cellular response to lipopolysaccharide NR1H4;BCR;SRC;ABL1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP3A43;CYP2C8;CYP3A5 GO:0008209| androgen metabolic process CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;NR1I2;CDK2;PPARA;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent NR1H4;NR1I2;PPARA;ABL1 GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4;CYP2C8 GO:0046628| positive regulation of insulin receptor signaling pathway SRC;NR1H4 GO:0006954| inflammatory response LYN;NR1H4;HCK GO:0050728| negative regulation of inflammatory response BCR;NR1H4;PPARA GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP3A7;CYP3A4;NR1I2 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0007165| signal transduction SRC;BCR;MAP2K1;NR1H4;NR1I2;LYN GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0002376| immune system process LYN;NR1H4;SRC;HCK GO:0036378| CYP3A4 GO:0032868| response to insulin stimulus LYN;PPARA GO:0002933| CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;SRC GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression MAP2K1;SRC;NR1I2 6283:[DB06616 DB08602] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;PDE7A;LYN 6284:[DB06616 DB06728] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP3A4 GO:0042493| response to drug SRC;ABCB1;LYN;CYP2E1 GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 6285:[DB06616 DB00522] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00522|Bentiromide HPN common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;HPN GO:0043066| negative regulation of apoptotic process HPN;SRC;HCK GO:0008360| regulation of cell shape HPN;HCK 6286:[DB06616 DB02004] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;DPP4;LYN;CDK2 GO:0007155| cell adhesion DPP4;SRC;HCK;ABL1 GO:0043542| endothelial cell migration ABL1;DPP4 GO:0031295| T cell costimulation LYN;DPP4;SRC 6287:[DB06616 DB09301] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways GO:0006954| inflammatory response LYN;CCL2;HCK GO:0010976| positive regulation of neuron projection development LYN;ARSB GO:0019221| cytokine-mediated signaling pathway CCL2;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;VEGFA;LYN GO:0031954| positive regulation of protein autophosphorylation SRC;VEGFA GO:0010632| regulation of epithelial cell migration ARSB;SRC GO:0000165| MAPKKK cascade MAP2K1;GDNF;MAP2K2;CCL2;CAMK2G GO:0010629| negative regulation of gene expression VEGFA;MAP2K2;MAP2K1 GO:0050885| neuromuscular process controlling balance BCR;ABL1;HEXB GO:0006914| autophagy ARSB;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;VEGFA;LYN GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;VEGFA GO:0006935| chemotaxis CCL2;MAP2K1 GO:0008284| positive regulation of cell proliferation GDNF;HCK;CDK2;LYN;VEGFA GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;CCL2 GO:0002576| platelet degranulation LYN;VEGFA GO:0051272| positive regulation of cellular component movement VEGFA;LYN GO:0043066| negative regulation of apoptotic process VEGFA;HCK;GDNF;SRC GO:0042327| positive regulation of phosphorylation VEGFA;LYN GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;CCL2;HCK GO:0048010| vascular endothelial growth factor receptor signaling pathway VEGFA;SRC GO:0007399| nervous system development CAMK2G;VEGFA;BDNF;GDNF GO:0008360| regulation of cell shape CCL2;VEGFA;HEXB;HCK GO:0045597| positive regulation of cell differentiation MAP2K1;GDNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;CDK2 GO:0007155| cell adhesion CCL2;ABL1;SRC;HCK GO:0048668| collateral sprouting BDNF;ABL1 GO:0051894| positive regulation of focal adhesion assembly VEGFA;ABL1 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;VEGFA GO:0007275| multicellular organismal development CAMK2G;CDK2;VEGFA GO:0007498| mesoderm development VEGFA;HCK GO:0010628| positive regulation of gene expression SRC;MAP2K1;VEGFA GO:0007411| axon guidance BDNF;SRC;GDNF GO:0043406| positive regulation of MAP kinase activity SRC;VEGFA GO:0031175| neuron projection development LYN;GDNF GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;CCL2;VEGFA GO:0045785| positive regulation of cell adhesion VEGFA;SRC GO:0007165| signal transduction LYN;CCL2;MAP2K1;SRC;GDNF;BCR GO:0007417| central nervous system development LYN;ARSB;SRC GO:0010595| positive regulation of endothelial cell migration ABL1;VEGFA GO:0030335| positive regulation of cell migration VEGFA;LYN GO:0043547| positive regulation of GTPase activity BCR;CCL2 GO:0071456| cellular response to hypoxia SRC;VEGFA GO:0048477| oogenesis SRC;HEXB GO:0030154| cell differentiation CAMK2G;VEGFA;HCK GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CCL2;CDK2;CAMK2G;MAP3K2 6288:[DB06616 DB05047] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways GO:0007411| axon guidance BDNF;SRC GO:0007165| signal transduction LYN;GRIA1;MAP2K1;SRC;GRIA2;BCR GO:0006810| transport GRIA4;GRIA3;ABCB1 GO:0048668| collateral sprouting ABL1;BDNF GO:0007399| nervous system development BDNF;CAMK2G 6289:[DB06616 DB07614] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;SRC;HPGDS;BCR GO:0006629| lipid metabolic process HPGDS;CYP3A4 6290:[DB06616 DB07838] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07838|(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE NMT2 common genes common pathways 6291:[DB06616 DB00876] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0006979| response to oxidative stress ABL1;ABCC2 GO:0007165| signal transduction MAP2K1;BCR;SRC;AGTR1;LYN GO:0006810| transport ABCB1;ABCC2 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ABL1 GO:0042493| response to drug LYN;ABCC2;ABCB1;SRC GO:0050727| regulation of inflammatory response AGTR1;HCK;LYN GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABCC2;ABL1 GO:0042127| regulation of cell proliferation AGTR1;ABL1;SRC GO:0032496| response to lipopolysaccharide ABCC2;BCR 6292:[DB06616 DB05316] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0048678| response to axon injury DRD2;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;HTR2A;HCK GO:0035556| intracellular signal transduction BCR;DRD2;SRC;LYN;CAMK2G GO:0042493| response to drug HTR2A;LYN;ABCB1;SRC;DRD2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;SRC;ABL1 GO:0016032| viral reproduction HCK;SRC;LYN;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0007165| signal transduction BCR;SRC;DRD2;MAP2K1;HTR2A;LYN GO:0030900| forebrain development DRD2;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;ABL1;MAP2K1;DRD2;SRC;MAP2K2 GO:0009636| response to toxin DRD2;LYN GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0030336| negative regulation of cell migration DRD2;BCR 6293:[DB06616 DB05607] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05607|PRX-08066 HTR2B common genes common pathways GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;HTR2B GO:0050715| positive regulation of cytokine secretion SRC;HTR2B GO:0007165| signal transduction HTR2B;SRC;BCR;MAP2K1;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;HTR2B;ABL1 GO:0043406| positive regulation of MAP kinase activity HTR2B;SRC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;HTR2B GO:0043066| negative regulation of apoptotic process HTR2B;SRC;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2B;HCK GO:0007507| heart development MAP2K1;HTR2B GO:0042493| response to drug LYN;SRC;ABCB1;HTR2B GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K2;MAP2K1 6294:[DB06616 DB03955] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03955|1-deoxymannojirimycin MAN2A1 common genes common pathways 6295:[DB06616 DB01414] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 6296:[DB06616 DB08647] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08647|TRAZEOLIDE IGKC common genes common pathways GO:0038096| IGKC;LYN;SRC;HCK;ABL1 GO:0002250| adaptive immune response LYN;IGKC GO:0050900| leukocyte migration SRC;IGKC;LYN GO:0045087| innate immune response HCK;SRC;ABL1;LYN;IGKC GO:0050853| B cell receptor signaling pathway LYN;IGKC;ABL1 GO:0038095| LYN;IGKC GO:0002376| immune system process SRC;HCK;IGKC;LYN 6297:[DB06616 DB03125] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 6298:[DB06616 DB08861] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08861|DPDPE SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3 6299:[DB06616 DB02140] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02140|N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide CTSH common genes common pathways GO:0070371| ERK1 and ERK2 cascade CTSH;MAP2K1;MAP2K2 GO:0002250| adaptive immune response LYN;CTSH GO:0008284| positive regulation of cell proliferation LYN;CDK2;CTSH;HCK GO:0043066| negative regulation of apoptotic process CTSH;SRC;HCK GO:0010634| positive regulation of epithelial cell migration SRC;CTSH GO:0010628| positive regulation of gene expression CTSH;MAP2K1;SRC GO:0006915| apoptotic process CTSH;ABL1 GO:0031648| protein destabilization CTSH;SRC GO:0030335| positive regulation of cell migration CTSH;LYN 6300:[DB06616 DB04714] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0016032| viral reproduction HCK;FDPS;SRC;LYN GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP2C8;CYP3A4 6301:[DB06616 DB06979] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06979|5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;ABL1 GO:0055114| oxidation-reduction process CYP3A4;HAO1;CYP2C8 6302:[DB06616 DB09477] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways GO:0006954| inflammatory response LYN;BDKRB1;HCK GO:0032496| response to lipopolysaccharide BDKRB1;BCR GO:0001933| negative regulation of protein phosphorylation LYN;BDKRB1 GO:0009612| response to mechanical stimulus BDKRB1;SRC GO:0016477| cell migration BDKRB1;SRC GO:0007204| elevation of cytosolic calcium ion concentration BDKRB1;ABL1 GO:0007165| signal transduction MAP2K1;SRC;BCR;BDKRB1;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;BDKRB1 6303:[DB06616 DB08402] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08402|2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID PPARG;NCOA2;RXRA common genes common pathways GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development MAP2K1;PPARG;RXRA GO:0045087| innate immune response PPARG;LYN;ABL1;SRC;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;CDK2;PPARG;NCOA2 GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0009612| response to mechanical stimulus PPARG;SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;RXRA;CDK2;PPARG;MAP3K2 GO:0042493| response to drug PPARG;LYN;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;ABL1 GO:0016032| viral reproduction HCK;SRC;RXRA;LYN GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PPARG GO:0014070| response to organic cyclic compound PPARG;LYN GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;SRC 6304:[DB06616 DB08795] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2;SLC22A5 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0006810| transport ABCB1;SLC15A2;SLC15A1 6305:[DB06616 DB07340] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07340|N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine AURKB;INCENP common genes common pathways GO:0008283| cell proliferation SRC;AURKB GO:0046777| protein autophosphorylation HCK;BCR;SRC;ABL1;AURKB;LYN;CAMK2G GO:0007049| cell cycle AURKB;SRC;CDK2;INCENP GO:0016310| phosphorylation AURKB;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;AURKB GO:0000278| mitotic cell cycle AURKB;ABL1 GO:0051301| cell division AURKB;CDK2;INCENP GO:1901796| AURKB;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AURKB 6306:[DB06616 DB13421] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13421|Edoxudine ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation LYN;ALB 6307:[DB06616 DB12023] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways GO:0007165| signal transduction IL5RA;LYN;MAP2K1;BCR;SRC GO:0065009| regulation of molecular function IL5RA;CAMK2G GO:0008283| cell proliferation SRC;IL5RA GO:0018108| peptidyl-tyrosine phosphorylation LYN;IL5RA;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0038096| LYN;FCGR3A;ABL1;HCK;SRC GO:0019221| cytokine-mediated signaling pathway HCK;IL5RA GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;IL5RA;CAMK2G 6308:[DB06616 DB05423] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05423|ORG-34517 NR3C1 common genes common pathways GO:0007165| signal transduction NR3C1;LYN;MAP2K1;SRC;BCR GO:0006915| apoptotic process ABL1;NR3C1 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0051301| cell division NR3C1;CDK2 6309:[DB06616 DB06898] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06898|4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol ESR1;NCOA2 common genes common pathways GO:0060065| uterus development ESR1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA2;ESR1 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0007165| signal transduction SRC;BCR;MAP2K1;ESR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 6310:[DB06616 DB04477] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04477|N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;GAPDHS 6311:[DB06616 DB05415] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05415|OSI-461 PDE5A common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;PDE5A GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PDE5A 6312:[DB06616 DB04618] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04618|4,6-DIDEOXY-4-{[4-[(4-O-HEXOPYRANOSYLHEXOPYRANOSYL)OXY]-5,6-DIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}HEXOPYRANOSYL-(1->4)HEXOPYRANOSYL-(1->4)HEXOPYRANOSE AMY2A common genes common pathways 6313:[DB06616 DB00431] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00431|Lindane GABRB1;GLRA1;GLRA2;GLRA3;GLRB;GABRB3;GABRR1;PGR;ESR1;NR1I2 common genes common pathways GO:0007165| signal transduction GABRB3;SRC;PGR;BCR;MAP2K1;ESR1;NR1I2;LYN;GABRB1 GO:0050847| progesterone receptor signaling pathway SRC;PGR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0006810| transport GABRR1;GABRB1;GABRB3;ABCB1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008202| steroid metabolic process NR1I2;CYP3A4;CYP2C8 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1I2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;NR1I2 GO:0009636| response to toxin LYN;GABRB1 GO:0043200| response to amino acid stimulus GLRA3;LYN;GLRB GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0007399| nervous system development GLRB;CAMK2G GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4;CYP2C8 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;ESR1;PGR;ABL1 GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4;CYP2C8 GO:0010629| negative regulation of gene expression PGR;MAP2K2;MAP2K1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;NR1I2;CDK2;ESR1;MAP2K1;SRC;MAP2K2 6314:[DB06616 DB06896] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MET GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;MET;CAMK2G GO:0035635| entry of bacterium into host cell MET;SRC GO:0018108| peptidyl-tyrosine phosphorylation MET;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0008283| cell proliferation MET;SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;MET;LYN GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;MET GO:0006468| protein phosphorylation MET;MAP3K2;CAMK2G;CDK2;LYN;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 6315:[DB06616 DB03981] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;ANXA5 GO:0002576| platelet degranulation LYN;ANXA5 GO:0008284| positive regulation of cell proliferation FGF2;CDK2;LYN;HCK GO:0006935| chemotaxis FGF2;MAP2K1 GO:0007399| nervous system development FGF2;CAMK2G GO:0007275| multicellular organismal development FGF2;CDK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN;FGF2 GO:0007265| Ras protein signal transduction CDK2;FGF2 GO:0000165| MAPKKK cascade FGF2;CAMK2G;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;FGF2 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;FGF2;MAP2K1;SRC;MAP2K2 GO:0007165| signal transduction BCR;SRC;MAP2K1;ANXA5;LYN;FGF2 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity FGF2;LYN;SRC GO:0072089| stem cell proliferation FGF2;ABCB1 GO:0030154| cell differentiation CAMK2G;FGF2;HCK GO:0010033| response to organic substance CDK2;ANXA5 GO:0043406| positive regulation of MAP kinase activity FGF2;SRC GO:0007596| blood coagulation LYN;ANXA5 GO:0000187| activation of MAPK activity FGF2;MAP3K2;MAP2K2;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF2;ABL1;MAP2K1;SRC;MAP2K2 6316:[DB06616 DB07968] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways 6317:[DB06616 DB03987] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 6318:[DB06616 DB04076] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug SRC;ABCB1;LYN;PNP;CYP1A2 6319:[DB06616 DB06512] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06512|Deramciclane HTR2A;HTR2C;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;HTR2A GO:0016032| viral reproduction LYN;HTR2A;HCK;SRC GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;SRC;HTR2C;HTR2A;LYN GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction HTR2A;LYN;BCR;SRC;MAP2K1;HTR2C GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;MAP2K2;SRC;MAP2K1;HTR2C;ABL1 6320:[DB06616 DB07403] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways GO:0008283| cell proliferation PDK1;SRC GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;PDK1;MAP3K2;CAMK2G;LYN;CDK2 GO:0016310| phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2;PDK1 6321:[DB06616 DB05971] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05971|Archexin AKT1 common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;AKT1 GO:0007399| nervous system development CAMK2G;AKT1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;AKT1;MAP3K2 GO:0032148| activation of protein kinase B activity SRC;AKT1 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;AKT1 GO:0071260| cellular response to mechanical stimulus MAP3K2;AKT1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;AKT1;SRC GO:0008284| positive regulation of cell proliferation HCK;AKT1;LYN;CDK2 GO:1901796| CDK2;AKT1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;AKT1 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN;AKT1 GO:0043066| negative regulation of apoptotic process AKT1;HCK;SRC GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G;AKT1 GO:0001934| positive regulation of protein phosphorylation ABL1;AKT1;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process AKT1;SRC GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;AKT1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;AKT1;CDK2 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;AKT1 GO:0006954| inflammatory response HCK;AKT1;LYN GO:0071456| cellular response to hypoxia SRC;AKT1 GO:0032869| cellular response to insulin stimulus SRC;AKT1 GO:0006468| protein phosphorylation AKT1;MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0030154| cell differentiation CAMK2G;AKT1;HCK GO:0030168| platelet activation SRC;LYN;AKT1 GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;AKT1;MAP3K2;CAMK2G;CDK2;LYN GO:0031295| T cell costimulation LYN;AKT1;SRC GO:0010907| positive regulation of glucose metabolic process AKT1;SRC GO:0009725| response to hormone stimulus LYN;AKT1 GO:0007165| signal transduction LYN;AKT1;MAP2K1;SRC;BCR GO:1900182| SRC;AKT1 GO:0006979| response to oxidative stress ABL1;AKT1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;AKT1;CAMK2G GO:0006915| apoptotic process AKT1;ABL1 GO:0008283| cell proliferation SRC;AKT1 GO:0006464| protein modification process ABL1;AKT1 GO:0010033| response to organic substance CDK2;AKT1 GO:0046777| protein autophosphorylation AKT1;CAMK2G;LYN;SRC;BCR;HCK;ABL1 GO:0034614| cellular response to reactive oxygen species SRC;AKT1 6322:[DB06616 DB02996] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02996|2-(Thiomethylene)-4-Methylpentanoic Acid ADAM28 common genes common pathways 6323:[DB06616 DB03821] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03821|2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid ARSA;ARSA common genes common pathways 6324:[DB06616 DB07999] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07999|{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process AKR1B1;SRC;HCK GO:0010033| response to organic substance AKR1B1;CDK2 6325:[DB06616 DB01273] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways GO:0000187| activation of MAPK activity MAP3K2;CHRNA7;MAP2K2;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;CHRNA7;ABL1 GO:0055085| transmembrane transport SLC22A2;ABCB1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0007165| signal transduction CHRNA7;MAP2K1;BCR;CHRNA3;CHRNA4;SRC;LYN;CHRNA6;CHRNB2 GO:0006810| transport CHRNA6;ABCB1 GO:0006816| calcium ion transport CAMK2G;CHRNB2;CHRNA7;CHRNA4 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;CHRNA7 GO:0008284| positive regulation of cell proliferation HCK;CHRNA7;CDK2;LYN GO:0006281| DNA repair CHRNA4;ABL1;CDK2 GO:0007399| nervous system development CAMK2G;CHRNA3 6326:[DB06616 DB08856] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08856|DADLE SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1 6327:[DB06616 DB07447] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0008209| androgen metabolic process AKR1D1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;AKR1D1 GO:0006629| lipid metabolic process CYP3A4;AKR1D1 GO:0008202| steroid metabolic process CYP3A4;AKR1D1;CYP2C8 6328:[DB06616 DB08729] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;PDE5A GO:0007165| signal transduction BCR;SRC;MAP2K1;PDE5A;LYN 6329:[DB06616 DB09037] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09037|Pembrolizumab PDCD1 common genes common pathways GO:0006915| apoptotic process ABL1;PDCD1 GO:0031295| T cell costimulation SRC;PDCD1;LYN GO:0002376| immune system process PDCD1;LYN;HCK;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;PDCD1;LYN GO:0007275| multicellular organismal development CDK2;CAMK2G;PDCD1 GO:0043066| negative regulation of apoptotic process HCK;SRC;PDCD1 GO:0043065| positive regulation of apoptotic process PDCD1;SRC;ABL1 6330:[DB06616 DB03194] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03194|beta-L-methyl-fucose MBL2 common genes common pathways GO:0045087| innate immune response ABL1;HCK;SRC;LYN;MBL2 GO:0050766| positive regulation of phagocytosis BCR;MBL2 GO:0006979| response to oxidative stress MBL2;ABL1 GO:0002376| immune system process LYN;MBL2;HCK;SRC 6331:[DB06616 DB08878] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4;CYP2C8 GO:0055085| transmembrane transport ABCB1;SLC46A1 6332:[DB06616 DB14146] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes ABCB1 common pathways GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug SRC;ABCB1;LYN GO:0010629| negative regulation of gene expression OPRD1;MAP2K2;MAP2K1 GO:0071222| cellular response to lipopolysaccharide ABL1;OPRK1;SRC;BCR GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:1901529| ABCB1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;OPRM1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;LYN;MAP2K1;SRC;BCR;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 6333:[DB06616 DB14029] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14029|Furafylline CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 6334:[DB06616 DB09107] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways GO:0007165| signal transduction EPOR;LYN;MAP2K1;SRC;BCR GO:0007420| brain development BCR;EPOR GO:0007507| heart development MAP2K1;EPOR GO:0019221| cytokine-mediated signaling pathway HCK;EPOR 6335:[DB06616 DB03005] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0007155| cell adhesion ACHE;ABL1;HCK;SRC GO:0007399| nervous system development CAMK2G;ACHE GO:0006260| DNA replication ACHE;CDK2 6336:[DB06616 DB00159] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0006810| transport TRPV1;ABCB1 GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0071456| cellular response to hypoxia SLC8A1;SRC;PTGS2;PPARD GO:0007204| elevation of cytosolic calcium ion concentration SLC8A1;TRPV1;ABL1 GO:0030154| cell differentiation PPARD;CAMK2G;HCK GO:0043434| response to peptide hormone stimulus LYN;TRPV1 GO:0034605| cellular response to heat LYN;PTGS2;TRPV1 GO:0065009| regulation of molecular function FFAR1;CAMK2G;TRPV1 GO:0070542| response to fatty acid FFAR1;PTGS2;SRC GO:0007420| brain development ACSL3;BCR GO:0007165| signal transduction FFAR1;LYN;PPARG;MAP2K1;BCR;SRC GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0006915| apoptotic process ABL1;PPARD GO:0055085| transmembrane transport TRPV1;ABCB1;SLC8A1 GO:0032868| response to insulin stimulus LYN;PPARA GO:0014070| response to organic cyclic compound PTGS2;ACSL3;PPARG;LYN GO:0030182| neuron differentiation MAP2K1;ABL1;ACSL4 GO:0008283| cell proliferation PPARD;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG;SRC GO:0008285| negative regulation of cell proliferation PPARG;LYN;FABP7;PTGS2;MAP2K1 GO:0010033| response to organic substance CDK2;PPARG;PPARD;PTGS2 GO:0034614| cellular response to reactive oxygen species SLC8A1;SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1;PPARD GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2;PPARD GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process ACSL4;TRPV1;PTGS1;FADS1;PPARG;PPARA;CYP3A4;PPARD;ACSL3;PTGS2 GO:0030073| insulin secretion CAMK2G;FFAR1 GO:0007399| nervous system development CAMK2G;FABP7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;PPARA;PPARG;CDK2;TRPV1 GO:0045087| innate immune response SRC;HCK;ABL1;PPARG;LYN GO:0007507| heart development PPARG;PPARA;PPARD;MAP2K1 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;PPARD;ALB;SRC;HCK GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2;PPARD GO:0042542| response to hydrogen peroxide SRC;SLC8A1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;PPARD GO:0043065| positive regulation of apoptotic process ABL1;SRC;TRPV1;PPARG;PTGS2 GO:0002576| platelet degranulation LYN;ALB GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;FADS1;CYP3A4;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;PPARA;PPARG;CDK2;MAP3K2;PPARD GO:0006355| regulation of transcription, DNA-dependent FADS1;PPARG;PPARA;PPARD;ABL1 GO:0042493| response to drug LYN;PPARG;PTGS2;SRC;SLC8A1;ABCB1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0051924| regulation of calcium ion transport SLC8A1;CAMK2G GO:0006816| calcium ion transport CAMK2G;TRPV1;SLC8A1 GO:0050728| negative regulation of inflammatory response BCR;PPARA;PPARD GO:0006954| inflammatory response HCK;PTGS1;TRPV1;PTGS2;LYN 6337:[DB06616 DB04903] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways GO:0006810| transport ABCB1;GABRA3 6338:[DB06616 DB04273] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04273|8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine PNMT common genes common pathways 6339:[DB06616 DB02831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02831|Dihydrogenphosphate DCXR common genes common pathways GO:0055114| oxidation-reduction process DCXR;CYP2C8;CYP3A4 6340:[DB06616 DB00649] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes common pathways GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0055085| transmembrane transport ABCB1;SLC22A6 6341:[DB06616 DB07406] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways GO:0046777| protein autophosphorylation MAPKAPK2;HCK;SRC;BCR;ABL1;LYN;CAMK2G GO:0000187| activation of MAPK activity MAP2K2;MAPKAPK2;MAP2K1;MAP3K2 GO:1900034| CAMK2G;MAPKAPK2 GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;MAPKAPK2;HCK GO:0006468| protein phosphorylation HCK;MAPKAPK2;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0006954| inflammatory response LYN;HCK;MAPKAPK2 GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAPKAPK2;MAP2K2 GO:0018105| peptidyl-serine phosphorylation SRC;MAPKAPK2;CAMK2G;CDK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;MAPKAPK2 GO:0006974| response to DNA damage stimulus ABL1;MAPKAPK2;CDK2;LYN GO:0032496| response to lipopolysaccharide MAPKAPK2;BCR GO:0007265| Ras protein signal transduction MAPKAPK2;CDK2 6342:[DB06616 DB00985] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00985|Dimenhydrinate HRH1 common genes common pathways GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0006954| inflammatory response LYN;HRH1;HCK GO:0007165| signal transduction LYN;HRH1;BCR;SRC;MAP2K1 6343:[DB06616 DB01643] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01643|Thymidine monophosphate tmk;DTYMK;dnaQ;TYMS;thyA;topA common genes common pathways GO:0007049| cell cycle DTYMK;CDK2;SRC GO:0014070| response to organic cyclic compound TYMS;LYN GO:0009636| response to toxin LYN;TYMS GO:0008283| cell proliferation DTYMK;SRC GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;DTYMK;LYN;CDK2;CAMK2G;MAP3K2 GO:0042493| response to drug SRC;ABCB1;TYMS;LYN 6344:[DB06616 DB00727] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ALDH2;CYP3A4 GO:0043114| regulation of vascular permeability NPR1;BCR;SRC GO:0035556| intracellular signal transduction BCR;SRC;NPR1;CAMK2G;LYN GO:0006468| protein phosphorylation HCK;MAP2K1;NPR1;SRC;MAP2K2;BCR;ABL1;MAP3K2;LYN;CDK2;CAMK2G 6345:[DB06616 DB00785] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007399| nervous system development CHRM2;CHRM1;CAMK2G;CHRM3 GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0007165| signal transduction CHRM1;LYN;CHRM2;CHRM5;CHRM3;BCR;SRC;MAP2K1;CHRM4 GO:0008283| cell proliferation CHRM3;CHRM5;CHRM1;CHRM4;SRC GO:0006464| protein modification process CHRM3;CHRM1;ABL1 6346:[DB06616 DB05197] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05197|Sofalcone CBR1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CBR1;CYP2C8 GO:0017144| drug metabolic process CBR1;CYP2C8;CYP3A4 6347:[DB06616 DB07369] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways GO:0008283| cell proliferation SRC;MET GO:0007165| signal transduction LYN;MET;SRC;BCR;MAP2K1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;MET GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MET;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;MET;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MET GO:0000165| MAPKKK cascade MET;CAMK2G;MAP2K1;MAP2K2 GO:0035635| entry of bacterium into host cell MET;SRC GO:0018108| peptidyl-tyrosine phosphorylation MET;LYN;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 6348:[DB06616 DB00988] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0055114| oxidation-reduction process DBH;CYP2C8;CYP2C19;CYP3A4;SOD1;MAOB;MAOA GO:0050900| leukocyte migration LYN;DBH;SRC GO:0031667| response to nutrient levels SRC;SOD1 GO:0006355| regulation of transcription, DNA-dependent ABL1;POU5F1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0042493| response to drug DRD2;SRC;ABCB1;SLC6A4;DRD1;SLC6A3;COMT;MAOB;SLC6A2;LYN;SOD1;DRD3 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0048678| response to axon injury LYN;SOD1;DRD2 GO:0007275| multicellular organismal development POU5F1;CAMK2G;CDK2 GO:0034599| cellular response to oxidative stress SOD1;ABL1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0032496| response to lipopolysaccharide COMT;MAOB;BCR GO:0001932| regulation of protein phosphorylation LYN;DRD1;MAP2K1 GO:0042127| regulation of cell proliferation SRC;DBH;ABL1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0000122| negative regulation of transcription from RNA polymerase II promoter POU5F1;DRD3;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;SOD1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0035556| intracellular signal transduction SRC;DRD2;BCR;LYN;CAMK2G GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0042542| response to hydrogen peroxide SOD1;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DRD3;HTR1A GO:0002576| platelet degranulation SOD1;LYN GO:0043065| positive regulation of apoptotic process SOD1;SRC;ABL1 GO:0000187| activation of MAPK activity DRD4;SOD1;MAP3K2;MAP2K2;MAP2K1 GO:0055085| transmembrane transport SLC6A2;SLC22A1;SLC22A3;SLC22A5;SLC18A2;ABCB1;SLC22A2;SLC6A3;SLC6A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;DRD2;MAP2K2;MAP2K1;ABL1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A5;SLC22A3;SLC22A1 GO:0009636| response to toxin MAOB;SLC18A2;LYN;DRD2;SLC6A4 GO:0014070| response to organic cyclic compound COMT;LYN;SLC6A3 GO:0008283| cell proliferation HTR1A;SRC GO:0010033| response to organic substance SOD1;CDK2;SLC6A4 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0010628| positive regulation of gene expression SLC6A4;DRD1;SRC;MAP2K1 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0006810| transport ABCB1;SLC6A2 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C19 GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0030900| forebrain development SRC;DRD2 GO:1903351| DRD1;ABL1 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8 GO:0097267| CYP2C8;CYP2C19 GO:0007165| signal transduction DRD4;HTR1A;LYN;DRD3;BCR;DRD2;SRC;MAP2K1;HTR3A;DRD5;HTR3B;HTR7;DRD1 GO:0007420| brain development SLC6A4;BCR GO:0006979| response to oxidative stress ABL1;SOD1 GO:0048538| thymus development SOD1;MAP2K1;ABL1 6349:[DB06616 DB00450] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00450|Droperidol DRD2;ADRA1A common genes common pathways GO:0048678| response to axon injury DRD2;LYN GO:0035556| intracellular signal transduction BCR;ADRA1A;SRC;DRD2;LYN;CAMK2G GO:0042493| response to drug ADRA1A;SRC;DRD2;ABCB1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0030900| forebrain development DRD2;SRC GO:0007165| signal transduction LYN;SRC;DRD2;ADRA1A;BCR;MAP2K1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0009636| response to toxin DRD2;LYN GO:0006915| apoptotic process ABL1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;DRD2;ADRA1A;MAP2K1;ABL1 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2;ADRA1A 6350:[DB06616 DB12742] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0030155| regulation of cell adhesion RET;ABL1 GO:0071300| cellular response to retinoic acid RET;LYN GO:2000249| regulation of actin cytoskeleton reorganization ABL1;PDGFRA GO:0035556| intracellular signal transduction LYN;CAMK2G;KIT;SRC;BCR GO:0035635| entry of bacterium into host cell SRC;MET GO:0006935| chemotaxis PDGFRA;MAP2K1 GO:0008284| positive regulation of cell proliferation KIT;HCK;PDGFRA;LYN;CDK2;FLT3 GO:0006974| response to DNA damage stimulus RAD51;ABL1;LYN;CDK2 GO:0006281| DNA repair CDK2;ABL1;RAD51 GO:0042981| regulation of apoptotic process MAP3K2;FLT3;MAP2K2;MAP2K1 GO:0007399| nervous system development CAMK2G;RET GO:0007155| cell adhesion HCK;SRC;RET;ABL1 GO:0008360| regulation of cell shape HCK;KIT GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC;PDGFRA GO:0001932| regulation of protein phosphorylation RAD51;MAP2K1;LYN GO:0042127| regulation of cell proliferation ABL1;KIT;SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;FLT3;MET;ABL1;MAP2K1;KIT;HCK;PDGFRA;MAP2K2;BCR;RET;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;FLT3;KIT GO:0007275| multicellular organismal development PDGFRA;CAMK2G;CDK2 GO:0016032| viral reproduction SRC;HCK;PDGFRA;LYN GO:0006954| inflammatory response KIT;HCK;LYN GO:0010976| positive regulation of neuron projection development RET;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;KIT;PDGFRA;MET GO:0030218| erythrocyte differentiation LYN;KIT GO:0000165| MAPKKK cascade PDGFRA;KIT;MAP2K1;RET;MAP2K2;MET;CAMK2G GO:0019221| cytokine-mediated signaling pathway FLT3;KIT;HCK GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;RET;SRC;MAP2K1;CDK2;MAP3K2 GO:0042493| response to drug RAD51;ABCB1;SRC;RET;LYN GO:0030097| hemopoiesis KIT;LYN;FLT3 GO:0065009| regulation of molecular function RET;CAMK2G GO:0051321| meiotic cell cycle RAD51;CDK2 GO:0007165| signal transduction LYN;MET;SRC;RET;BCR;KIT;MAP2K1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;LYN;FLT3;RET;KIT;HCK;PDGFRA GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity PDGFRA;KIT;SRC;FLT3;LYN GO:0030335| positive regulation of cell migration RET;PDGFRA;KIT;LYN GO:0016310| phosphorylation MET;MAP3K2;CAMK2G;LYN;CDK2;FLT3;BCR;MAP2K2;SRC;RET;KIT;MAP2K1;PDGFRA;HCK;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;PDGFRA GO:0006468| protein phosphorylation LYN;CDK2;FLT3;CAMK2G;MAP3K2;MET;ABL1;KIT;MAP2K1;PDGFRA;HCK;BCR;MAP2K2;SRC;RET GO:0030154| cell differentiation CAMK2G;FLT3;HCK GO:0034614| cellular response to reactive oxygen species PDGFRA;SRC GO:0010628| positive regulation of gene expression MAP2K1;KIT;RET;SRC GO:0046777| protein autophosphorylation ABL1;BCR;SRC;KIT;PDGFRA;HCK;CAMK2G;LYN;FLT3 GO:0097028| dendritic cell differentiation FLT3;LYN GO:0007411| axon guidance SRC;RET GO:0043406| positive regulation of MAP kinase activity SRC;KIT;FLT3 GO:0009636| response to toxin LYN;RAD51 GO:0014070| response to organic cyclic compound LYN;RAD51 GO:0030182| neuron differentiation ABL1;MAP2K1;RET GO:0008283| cell proliferation MET;SRC GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;KIT;MAP3K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;PDGFRA;MAP2K1;ABL1 6351:[DB06616 DB07920] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07920|N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;MMP12 GO:0010628| positive regulation of gene expression MMP12;SRC;MAP2K1 6352:[DB06616 DB00737] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00737|Meclizine HRH1;NR1I3 common genes common pathways GO:0006954| inflammatory response LYN;HRH1;HCK GO:0006355| regulation of transcription, DNA-dependent NR1I3;ABL1 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;SRC GO:0007165| signal transduction NR1I3;HRH1;LYN;BCR;SRC;MAP2K1 6353:[DB06616 DB03828] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03828|RU78299 SRC common genes SRC common pathways GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation CAMK2G;LYN;ABL1;BCR;SRC;HCK GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0010447| response to acidity SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0031295| T cell costimulation SRC;LYN GO:0036120| SRC GO:0007417| central nervous system development SRC;LYN GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0071456| cellular response to hypoxia SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0036035| osteoclast development SRC GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0048477| oogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0002376| immune system process SRC;HCK;LYN GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0038083| ABL1;HCK;SRC;LYN GO:0042493| response to drug LYN;ABCB1;SRC GO:0034332| adherens junction organization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0050900| leukocyte migration SRC;LYN GO:0016032| viral reproduction LYN;HCK;SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0071498| cellular response to fluid shear stress SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0038128| SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038096| LYN;ABL1;SRC;HCK GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC GO:0045056| transcytosis SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0086098| SRC GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0009615| response to virus SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0035635| entry of bacterium into host cell SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0007155| cell adhesion ABL1;HCK;SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0045087| innate immune response LYN;ABL1;HCK;SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC 6354:[DB06616 DB04098] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04098|Balanol PRKACA common genes common pathways GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2 GO:0002223| stimulatory C-type lectin receptor signaling pathway PRKACA;LYN;SRC GO:0043393| regulation of protein binding PRKACA;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;PRKACA;CDK2 GO:0007596| blood coagulation PRKACA;LYN GO:0000086| G2/M transition of mitotic cell cycle CDK2;PRKACA;ABCB1 GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;PRKACA;LYN;CDK2;CAMK2G;MAP3K2 GO:0034605| cellular response to heat LYN;PRKACA GO:0006468| protein phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;PRKACA;MAP3K2 6355:[DB06616 DB02240] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02240|Quinacrine mustard TPR common genes common pathways GO:0007049| cell cycle TPR;CDK2;SRC GO:0034605| cellular response to heat TPR;LYN GO:1900034| CAMK2G;TPR GO:0051301| cell division TPR;CDK2 GO:0016032| viral reproduction HCK;SRC;LYN;TPR GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TPR 6356:[DB06616 DB08240] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways GO:0002576| platelet degranulation LYN;ALDOA GO:0008360| regulation of cell shape ALDOA;HCK 6357:[DB06616 DB08697] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08697|4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0006935| chemotaxis PLAU;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;PLAU GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0007596| blood coagulation PLAU;LYN GO:0007165| signal transduction SRC;BCR;MAP2K1;PLAU;LYN GO:0030335| positive regulation of cell migration PLAU;LYN 6358:[DB06616 DB06043] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06043|Olaratumab PDGFRA common genes common pathways GO:0016310| phosphorylation ABL1;PDGFRA;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;PDGFRA GO:0030335| positive regulation of cell migration PDGFRA;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;PDGFRA;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;PDGFRA GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;PDGFRA;ABL1 GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;PDGFRA;HCK;BCR;SRC GO:0034614| cellular response to reactive oxygen species PDGFRA;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;PDGFRA GO:0008284| positive regulation of cell proliferation PDGFRA;HCK;CDK2;LYN GO:0006935| chemotaxis PDGFRA;MAP2K1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1;PDGFRA GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR;PDGFRA GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;PDGFRA;HCK;ABL1;LYN GO:0007275| multicellular organismal development CAMK2G;CDK2;PDGFRA GO:0016032| viral reproduction LYN;SRC;HCK;PDGFRA GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRA;SRC GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;PDGFRA;CAMK2G 6359:[DB06616 DB08513] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08513|[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID MAPK1;INSR;IRS1 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;INSR;LYN GO:0032496| response to lipopolysaccharide MAPK1;BCR GO:0007507| heart development MAP2K1;MAPK1 GO:0032148| activation of protein kinase B activity INSR;SRC GO:0006974| response to DNA damage stimulus ABL1;MAPK1;CDK2;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;MAPK1 GO:0006935| chemotaxis MAP2K1;MAPK1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;IRS1;MAPK1;INSR GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;MAPK1;HCK GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN;MAPK1;INSR GO:0023014| signal transduction via phosphorylation event LYN;INSR GO:0001934| positive regulation of protein phosphorylation ABL1;INSR;LYN GO:0060425| lung morphogenesis MAPK1;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent INSR;MAPK1;ABL1 GO:0038083| SRC;HCK;ABL1;INSR;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAPK1;INSR;MAP3K2;CDK2;MAP2K2;SRC;MAP2K1 GO:0060440| trachea formation MAP2K1;MAPK1 GO:2000641| regulation of early endosome to late endosome transport MAPK1;MAP2K1;SRC;MAP2K2 GO:0038096| ABL1;HCK;SRC;LYN;MAPK1 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1;MAPK1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;INSR;IRS1 GO:0046628| positive regulation of insulin receptor signaling pathway SRC;IRS1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G;MAPK1;IRS1 GO:0060324| face development MAPK1;MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAPK1;MAP2K2;MAP2K1 GO:0016032| viral reproduction MAPK1;LYN;SRC;HCK GO:0032869| cellular response to insulin stimulus IRS1;INSR;SRC GO:0006468| protein phosphorylation MAP3K2;INSR;MAPK1;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0030168| platelet activation LYN;MAPK1;SRC GO:0016310| phosphorylation MAPK1;MAP3K2;INSR;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway INSR;LYN;HCK GO:0043434| response to peptide hormone stimulus IRS1;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity IRS1;LYN;SRC GO:0030335| positive regulation of cell migration INSR;MAPK1;LYN GO:0010907| positive regulation of glucose metabolic process IRS1;SRC GO:0007165| signal transduction LYN;IRS1;MAPK1;MAP2K1;BCR;SRC GO:0051090| regulation of sequence-specific DNA binding transcription factor activity MAPK1;HCK GO:1903351| MAPK1;ABL1 GO:0048538| thymus development MAP2K1;ABL1;MAPK1 GO:0030878| thyroid gland development MAP2K1;MAPK1 GO:1900034| CAMK2G;MAPK1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAPK1;MAP2K1 GO:0032868| response to insulin stimulus IRS1;LYN GO:0006915| apoptotic process MAPK1;ABL1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1;MAPK1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;INSR;MAP3K2;MAPK1 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway MAPK1;LYN GO:0038095| MAPK1;LYN GO:0009636| response to toxin LYN;MAPK1 GO:0090170| regulation of Golgi inheritance MAP2K2;MAP2K1;MAPK1 GO:0007411| axon guidance MAPK1;SRC GO:0007049| cell cycle SRC;CDK2;MAPK1 GO:0046777| protein autophosphorylation HCK;SRC;BCR;ABL1;INSR;LYN;CAMK2G GO:0050853| B cell receptor signaling pathway MAPK1;LYN;ABL1 GO:0034614| cellular response to reactive oxygen species SRC;MAPK1 GO:0010628| positive regulation of gene expression MAPK1;MAP2K1;SRC 6360:[DB06616 DB01579] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;ADRA1B GO:0035556| intracellular signal transduction BCR;SRC;ADRA1A;ADRA1B;CAMK2G;LYN GO:0042493| response to drug ABCB1;SRC;ADRA1A;LYN;SLC6A2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1B;ADRA1A GO:0006810| transport SLC6A2;ABCB1 GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;ADRA1A;ADRA1B GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0008283| cell proliferation ADRA1B;SRC GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;ADRA1A;MAP2K2;MAP2K1;ABL1 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;ADRA1A 6361:[DB06616 DB03848] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03848|Benzenesulfinic acid NR1H2 common genes common pathways GO:0010629| negative regulation of gene expression NR1H2;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent NR1H2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;NR1H2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H2;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1H2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;NR1H2 6362:[DB06616 DB05964] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0030900| forebrain development DRD2;SRC GO:0007165| signal transduction MAP2K1;DRD2;SRC;BCR;LYN GO:0007420| brain development SLC6A4;BCR GO:0006810| transport SLC6A2;ABCB1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;SLC6A4 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0010033| response to organic substance CDK2;SLC6A4 GO:0008285| negative regulation of cell proliferation LYN;DRD2;MAP2K1 GO:0009636| response to toxin SLC6A4;DRD2;LYN GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;DRD2;MAP2K2;ABL1 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;DRD2;SRC GO:0071300| cellular response to retinoic acid SLC6A4;LYN GO:0048678| response to axon injury LYN;DRD2 GO:0051259| protein oligomerization CAMK2G;SLC6A4 GO:0042493| response to drug SLC6A4;ABCB1;SRC;DRD2;LYN;SLC6A2 6363:[DB06616 DB05129] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;TOP1;SRC GO:0006974| response to DNA damage stimulus ABL1;TOP2A;LYN;CDK2 GO:0016032| viral reproduction SRC;HCK;TOP1;LYN GO:0006260| DNA replication CDK2;TOP1 GO:0042493| response to drug ABCB1;SRC;TOP1;LYN GO:0016310| phosphorylation MAP3K2;TOP1;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 6364:[DB06616 DB07359] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07359|3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide GCK common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;GCK GO:0016310| phosphorylation LYN;CDK2;CAMK2G;MAP3K2;GCK;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC 6365:[DB06616 DB07753] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR 6366:[DB06616 DB07875] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07875|5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0030335| positive regulation of cell migration F10;LYN GO:0007596| blood coagulation F10;LYN 6367:[DB06616 DB01034] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways GO:0006629| lipid metabolic process FASN;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;FASN;CYP2C8 6368:[DB06616 DB07555] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways GO:0007155| cell adhesion ABL1;HCK;SRC;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0006260| DNA replication ACHE;CDK2 GO:0008283| cell proliferation SRC;ACHE 6369:[DB06616 DB07011] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0055114| oxidation-reduction process NOS2;CYP3A4;CYP2C8 GO:0042127| regulation of cell proliferation NOS2;SRC;ABL1 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NOS2 6370:[DB06616 DB08773] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08773|RALOXIFENE CORE ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 GO:0060065| uterus development ESR1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;CDK2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1;NCOA2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 6371:[DB06616 DB03867] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways GO:0034599| cellular response to oxidative stress GSR;ABL1 GO:0055114| oxidation-reduction process GSR;CYP2C8;CYP3A4 6372:[DB06616 DB03568] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03568|Butyric Acid BCHE;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0042493| response to drug LYN;BCHE;SRC;ABCB1 6373:[DB06616 DB01861] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 6374:[DB06616 DB09137] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09137|Technetium Tc-99m mebrofenin SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 6375:[DB06616 DB03046] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03046|7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0007596| blood coagulation LYN;PLAU GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007165| signal transduction PLAU;SRC;BCR;MAP2K1;LYN GO:0030335| positive regulation of cell migration LYN;PLAU GO:0006935| chemotaxis MAP2K1;PLAU GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC 6376:[DB06616 DB04557] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NR1H4 GO:0050727| regulation of inflammatory response HCK;FABP4;LYN GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process NR1H4;SRC;HCK;ALB GO:0071398| cellular response to fatty acid SRC;NR1H4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8;PTGS1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;CDK2;RXRA;PPARA GO:0045087| innate immune response SRC;HCK;ABL1;NR1H4;LYN GO:0007507| heart development MAP2K1;RXRA;PPARA GO:0006629| lipid metabolic process PTGS1;CYP2C9;CYP3A4;PPARA GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade NR1H4;ABL1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0050728| negative regulation of inflammatory response NR1H4;PPARA;BCR GO:0006954| inflammatory response HCK;PTGS1;NR1H4;LYN GO:0016032| viral reproduction LYN;RXRA;HCK;SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC;NR1H4 GO:0006355| regulation of transcription, DNA-dependent NR1H4;PPARA;RXRA;ABL1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;RXRA;CDK2;PPARA GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8;PTGS1 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0002376| immune system process HCK;SRC;NR1H4;LYN GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0007165| signal transduction NR1H4;LYN;MAP2K1;SRC;BCR GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0045892| negative regulation of transcription, DNA-dependent FABP4;SRC GO:0055085| transmembrane transport ABCB1;SLCO2A1 GO:0032868| response to insulin stimulus LYN;PPARA 6377:[DB06616 DB09300] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways GO:0008283| cell proliferation CHRM3;SRC GO:0006464| protein modification process ABL1;CHRM3 GO:0007165| signal transduction CHRM2;LYN;CHRM3;MAP2K1;SRC;BCR GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM2;CAMK2G;CHRM3 6378:[DB06616 DB03884] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03884|Phenylpyruvic acid HAO1;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HAO1 GO:0050900| leukocyte migration SRC;SLC16A3;LYN GO:0006979| response to oxidative stress ABL1;HAO1 GO:0055085| transmembrane transport SLC16A3;ABCB1 6379:[DB06616 DB02082] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways GO:0034332| adherens junction organization SRC;RAB8B 6380:[DB06616 DB05831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05831|ING-1 EPCAM common genes common pathways GO:0050900| leukocyte migration LYN;SRC;EPCAM GO:0008284| positive regulation of cell proliferation CDK2;LYN;EPCAM;HCK GO:0098609| EPCAM;SRC 6381:[DB06616 DB06995] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways GO:0016310| phosphorylation MAP3K2;MET;CDK2;LYN;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;MET GO:0006468| protein phosphorylation MAP3K2;MET;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0007165| signal transduction LYN;MET;MAP2K1;BCR;SRC GO:0008283| cell proliferation SRC;MET GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MET;LYN GO:0035635| entry of bacterium into host cell SRC;MET GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MET GO:0000165| MAPKKK cascade MET;CAMK2G;MAP2K2;MAP2K1 6382:[DB06616 DB07929] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07929|N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE NR1H3;RXRB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H3;CDK2 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;NR1H3;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K2;SRC;MAP2K1;NR1H3 GO:0006355| regulation of transcription, DNA-dependent NR1H3;ABL1;RXRB GO:0050728| negative regulation of inflammatory response NR1H3;BCR 6383:[DB06616 DB07479] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways GO:0006974| response to DNA damage stimulus POLB;ABL1;CDK2;LYN GO:0006281| DNA repair ABL1;POLB;CDK2 GO:0048872| homeostasis of number of cells BCR;POLB GO:0006260| DNA replication POLB;CDK2 GO:0006954| inflammatory response LYN;HCK;POLB GO:0048536| spleen development ABL1;POLB GO:0006915| apoptotic process POLB;ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;POLB 6384:[DB06616 DB00870] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042493| response to drug SRC;ABCB1;LYN;UGT1A1;PTGS2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;CYP2C9;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;PTGS2;HCK GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;PTGS1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2;UGT2B7;PTGS1 GO:0032496| response to lipopolysaccharide BCR;PTGS2;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC;ABL1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0010033| response to organic substance PTGS2;UGT1A1;CDK2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;LYN GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0070542| response to fatty acid SRC;PTGS2 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT1A1;CYP2C8;UGT2B7 GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC 6385:[DB06616 DB03784] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03784|Elaidoylamide PLA2G2A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2A GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;PLA2G2A 6386:[DB06616 DB06199] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06199|Atrasentan EDNRA common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;EDNRA GO:0007165| signal transduction EDNRA;LYN;BCR;SRC;MAP2K1 GO:0008283| cell proliferation SRC;EDNRA GO:0007507| heart development EDNRA;MAP2K1 6387:[DB06616 DB04998] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04998|AGRO100 IKBKG common genes common pathways GO:0038095| LYN;IKBKG GO:0006915| apoptotic process IKBKG;ABL1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;IKBKG;MAP3K2 GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;SRC;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ABL1 GO:0009615| response to virus IKBKG;SRC GO:0045087| innate immune response LYN;SRC;HCK;IKBKG;ABL1 GO:0006974| response to DNA damage stimulus CDK2;LYN;ABL1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ABL1;IKBKG GO:0006954| inflammatory response IKBKG;HCK;LYN GO:0016032| viral reproduction LYN;HCK;SRC;IKBKG 6388:[DB06616 DB08130] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes MAP2K1 common pathways GO:0030182| neuron differentiation MAP2K1;ABL1 GO:0030216| keratinocyte differentiation MAP2K1 GO:0060711| labyrinthine layer development MAP2K1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;MAP2K1 GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0006928| cellular component movement MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0090170| regulation of Golgi inheritance MAP2K1;MAP2K2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:1903800| MAP2K1;MAP2K2 GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0048538| thymus development ABL1;MAP2K1 GO:0030878| thyroid gland development MAP2K1 GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1 GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K2;MAP2K1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;MAP3K2 GO:0035897| proteolysis in other organism MAP2K1;MAP2K2 GO:0060440| trachea formation MAP2K1 GO:0060425| lung morphogenesis MAP2K1 GO:0060324| face development MAP2K1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;MAP2K2 GO:0090398| cellular senescence MAP2K1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0060502| epithelial cell proliferation involved in lung morphogenesis MAP2K1 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2 GO:0001932| regulation of protein phosphorylation MAP2K1;LYN GO:0048870| cell motility MAP2K1 GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;LYN GO:0048679| regulation of axon regeneration MAP2K1 GO:0060674| placenta blood vessel development MAP2K1 GO:0006935| chemotaxis MAP2K1 GO:0021697| cerebellar cortex formation MAP2K1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2 GO:0007507| heart development MAP2K1 GO:0045597| positive regulation of cell differentiation MAP2K1 GO:0050772| positive regulation of axonogenesis MAP2K1 6389:[DB06616 DB00028] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:1901216| ABL1;FCGR2B GO:0001934| positive regulation of protein phosphorylation LYN;C3;ABL1 GO:0006954| inflammatory response C4A;C4B;HCK;C5;FCGR2B;C3;LYN GO:0016032| viral reproduction FCGR2B;LYN;SRC;HCK GO:0038096| FCGR3A;LYN;FCGR2B;HCK;SRC;FCGR1A;FCGR2A;ABL1 GO:0002250| adaptive immune response FCGR1B;LYN GO:0006935| chemotaxis MAP2K1;C5 GO:0045087| innate immune response C3;LYN;C5;C4A;FCGR1A;ABL1;HCK;SRC;C4B GO:0050777| negative regulation of immune response FCGR2B;LYN GO:0006629| lipid metabolic process CYP3A4;C3 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;C5;MAP3K2 GO:0050766| positive regulation of phagocytosis BCR;FCGR2B;C3 GO:0030889| negative regulation of B cell proliferation LYN;FCGR2B GO:0060333| interferon-gamma-mediated signaling pathway FCGR1A;HCK;CAMK2G;FCGR1B GO:0002376| immune system process FCGR1B;C5;C3;LYN;C4B;SRC;HCK;C4A;FCGR2A;FCGR1A GO:0007165| signal transduction FCGR2C;C3;LYN;FCGR2B;MAP2K1;BCR;SRC;FCGR1A 6390:[DB06616 DB04622] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways GO:0006464| protein modification process QPCT;ABL1 6391:[DB06616 DB06196] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;ANPEP GO:0043114| regulation of vascular permeability SRC;BCR;BDKRB2 GO:0016032| viral reproduction SRC;HCK;ANPEP;LYN GO:0006954| inflammatory response HCK;BDKRB2;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;BDKRB2;LYN GO:0030154| cell differentiation HCK;ANPEP;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;BDKRB2 GO:0007165| signal transduction LYN;BDKRB2;ANPEP;SRC;BCR;MAP2K1 6392:[DB06616 DB00366] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00366|Doxylamine HRH1;CHRM1;NR1I3;CYP2B common genes common pathways GO:0007399| nervous system development CAMK2G;CHRM1 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CHRM1 GO:0006954| inflammatory response HCK;HRH1;LYN GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1I3 GO:0007165| signal transduction LYN;CHRM1;NR1I3;HRH1;MAP2K1;BCR;SRC GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;SRC GO:0006464| protein modification process CHRM1;ABL1 GO:0008283| cell proliferation CHRM1;SRC 6393:[DB06616 DB01442] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0042493| response to drug ABCB1;SRC;SLC6A3;SLC6A4;SLC6A2;MAOB;HTR2A;LYN GO:0055114| oxidation-reduction process MAOB;MAOA;CYP3A4;CYP2C8 GO:0016032| viral reproduction LYN;HTR2A;SRC;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0006810| transport SLC6A2;ABCB1 GO:0007165| signal transduction HTR2A;LYN;BCR;SRC;MAP2K1 GO:0007420| brain development SLC6A4;BCR GO:0009636| response to toxin SLC6A4;MAOB;SLC18A2;LYN GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0006855| drug transmembrane transport SLC18A1;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;ABL1;MAP2K2;SRC;MAP2K1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A4;SLC6A2;SLC18A1;SLC18A2 GO:0009791| post-embryonic development ABL1;SLC18A2 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010033| response to organic substance CDK2;SLC6A4 6394:[DB06616 DB06980] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06980|(2S)-2-(1H-indol-3-yl)hexanoic acid SKP1 common genes common pathways GO:0038095| SKP1;LYN GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1;SKP1 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;SKP1;LYN 6395:[DB06616 DB07139] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07139|3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CDK2 GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC GO:0055114| oxidation-reduction process CYP3A4;AKR1B1;CYP2C8 6396:[DB06616 DB07760] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07760|3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;SRC;HCK GO:0006281| DNA repair ABL1;CDK2;UNG GO:0006974| response to DNA damage stimulus ABL1;UNG;LYN;CDK2 GO:0016032| viral reproduction HCK;SRC;LYN;UNG 6397:[DB06616 DB06900] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways GO:0065009| regulation of molecular function PRSS8;CAMK2G 6398:[DB06616 DB00899] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;OPRD1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;OPRK1 GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;LYN;MAP2K1;BCR;SRC;OPRK1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1 6399:[DB06616 DB00218] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006974| response to DNA damage stimulus LYN;CDK2;TOP2A;ABL1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0043065| positive regulation of apoptotic process SRC;ABL1;TOP2A GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 6400:[DB06616 DB13530] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13530|Mepindolol CYP2D6 common genes common pathways GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 6401:[DB06616 DB08842] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08842|Acetylcarnitine SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport ABCB1;SLC22A5 6402:[DB06616 DB03708] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways GO:0016310| phosphorylation ABL1;MAP2K1;PAPSS1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 6403:[DB06616 DB05199] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05199|LX1031 TPH1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;TPH1 6404:[DB06616 DB05882] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05882|CHF 4227 ESR1;ESR2 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0007165| signal transduction MAP2K1;SRC;BCR;ESR2;LYN;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR2;ESR1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;ESR2;MAP3K2;CDK2;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0060065| uterus development ESR1;SRC GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;ESR1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;ESR2 6405:[DB06616 DB08249] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;ABL1;DHODH GO:0042493| response to drug LYN;DHODH;SRC;ABCB1 GO:0055114| oxidation-reduction process DHODH;CYP2C8;CYP3A4 GO:0014070| response to organic cyclic compound DHODH;LYN 6406:[DB06616 DB13165] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0051894| positive regulation of focal adhesion assembly ABL1;ROCK1 GO:0035556| intracellular signal transduction SRC;BCR;ROCK1;LYN;ROCK2;CAMK2G GO:2000145| regulation of cell motility ROCK1;ABL1;ROCK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway ROCK2;SRC;ROCK1 GO:0030155| regulation of cell adhesion ROCK2;ABL1;ROCK1 GO:0051298| centrosome duplication CDK2;ROCK2 GO:0010506| regulation of autophagy ROCK1;ABL1 GO:0050900| leukocyte migration LYN;SRC;ROCK1 GO:0001934| positive regulation of protein phosphorylation ROCK2;LYN;ABL1 GO:0030036| actin cytoskeleton organization BCR;ABL1;ROCK1;ROCK2 GO:0010595| positive regulation of endothelial cell migration ROCK2;ABL1 GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;ROCK2;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;ROCK1 GO:0006468| protein phosphorylation MAP3K2;ROCK2;CAMK2G;LYN;CDK2;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;ROCK1 GO:0032956| regulation of actin cytoskeleton organization ROCK2;ABL1;ROCK1 GO:0007165| signal transduction ROCK1;SRC;BCR;MAP2K1;LYN GO:0031175| neuron projection development ROCK1;LYN GO:0006915| apoptotic process ROCK1;ABL1 GO:0010628| positive regulation of gene expression ROCK2;ROCK1;MAP2K1;SRC GO:0048013| ephrin receptor signaling pathway ROCK1;SRC;ROCK2;LYN 6407:[DB06616 DB04779] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04779|ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 6408:[DB06616 DB03346] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0008202| steroid metabolic process CYP3A4;SULT1E1;CYP2C8 GO:0006810| transport ABCB1;TTR 6409:[DB06616 DB07208] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways GO:0014070| response to organic cyclic compound LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation PPARG;LYN;MAP2K1 GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;PPARG;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug LYN;PPARG;SRC;ABCB1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development PPARG;MAP2K1 GO:0045087| innate immune response HCK;SRC;ABL1;LYN;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG 6410:[DB06616 DB09093] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways GO:0002576| platelet degranulation ALB;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 6411:[DB06616 DB07744] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways GO:0010506| regulation of autophagy CASP1;ABL1 GO:0032496| response to lipopolysaccharide BCR;CASP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;CASP1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;CASP1 GO:0050727| regulation of inflammatory response LYN;CASP1;HCK GO:0071260| cellular response to mechanical stimulus CASP1;MAP3K2 GO:0051882| mitochondrial depolarization CASP1;ABL1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;CASP1;MAP3K2 GO:0006915| apoptotic process CASP1;ABL1 GO:0050715| positive regulation of cytokine secretion SRC;CASP1 GO:0007165| signal transduction LYN;CASP1;MAP2K1;BCR;SRC 6412:[DB06616 DB13443] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13443|Esatenolol CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 6413:[DB06616 DB05642] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0042493| response to drug ABCB1;SRC;LYN;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0007165| signal transduction LYN;SRC;BCR;HTR3A;MAP2K1 GO:0006810| transport ABCB1;SLC6A2 6414:[DB06616 DB08584] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways GO:0008283| cell proliferation SRC;MET GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;LYN;CDK2;CAMK2G;MAP3K2;MET GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MET;MAP3K2;CAMK2G;LYN;CDK2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;MET GO:0007165| signal transduction MET;LYN;MAP2K1;BCR;SRC GO:0051897| positive regulation of protein kinase B signaling cascade MET;SRC GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G;MET GO:0018108| peptidyl-tyrosine phosphorylation MET;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0035635| entry of bacterium into host cell SRC;MET 6415:[DB06616 DB04859] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04859|Zanapezil ACHE common genes common pathways GO:0006260| DNA replication ACHE;CDK2 GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0008283| cell proliferation ACHE;SRC 6416:[DB06616 DB12548] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12548|Sparsentan AGT;EDNRA common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;AGT;EDNRA GO:0010595| positive regulation of endothelial cell migration AGT;ABL1 GO:0065009| regulation of molecular function CAMK2G;AGT GO:0003014| renal system process BCR;AGT GO:0007165| signal transduction EDNRA;LYN;BCR;SRC;MAP2K1 GO:0050663| cytokine secretion AGT;LYN GO:0008283| cell proliferation EDNRA;SRC GO:0042127| regulation of cell proliferation AGT;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus AGT;MAP3K2 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;MAP2K1;AGT GO:0007507| heart development MAP2K1;EDNRA GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;AGT GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K2;SRC;MAP2K1;AGT GO:0010629| negative regulation of gene expression MAP2K2;AGT;MAP2K1 GO:0051924| regulation of calcium ion transport CAMK2G;AGT GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;AGT;ABL1;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;AGT GO:0010976| positive regulation of neuron projection development LYN;AGT 6417:[DB06616 DB00245] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2D6;CYP3A4 GO:0097267| CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;BCR;HRH1;LYN;CHRM1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0055085| transmembrane transport SLC6A3;ABCB1 GO:0008283| cell proliferation CHRM1;SRC GO:0014070| response to organic cyclic compound SLC6A3;LYN GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006464| protein modification process ABL1;CHRM1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0007399| nervous system development CAMK2G;CHRM1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;CHRM1;LYN;CDK2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1;SLC6A3 GO:0006954| inflammatory response HCK;LYN;HRH1 6418:[DB06616 DB07269] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 6419:[DB06616 DB00792] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction HRH1;LYN;BCR;SRC;MAP2K1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0006954| inflammatory response HCK;HRH1;LYN GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 6420:[DB06616 DB04447] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04447|1,4-Dithiothreitol acpS;hisD;aroE;LGALS1;CAMK2A;rpmA;ALDH1A1;TRPM7;moaA;MSRA;AXIN1;PPIB;thyA;TPI1;GSTZ1;HMGCR;prfA common genes common pathways GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;CAMK2A;SRC GO:0008284| positive regulation of cell proliferation HCK;HMGCR;LYN;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SRC;HMGCR GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;CAMK2A;SRC GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;MAP2K2;LGALS1 GO:0007399| nervous system development CAMK2A;CAMK2G GO:0006629| lipid metabolic process HMGCR;CYP3A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LGALS1;ABL1 GO:0048678| response to axon injury LGALS1;LYN GO:0007275| multicellular organismal development AXIN1;CAMK2G;CDK2;TPI1 GO:0006816| calcium ion transport CAMK2A;CAMK2G;TRPM7 GO:0000082| G1/S transition of mitotic cell cycle CDK2;CAMK2G;CAMK2A GO:0000165| MAPKKK cascade CAMK2G;MAP2K2;CAMK2A;MAP2K1 GO:0042493| response to drug LYN;ABCB1;SRC;LGALS1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;MAP2K2;AXIN1;SRC GO:0055114| oxidation-reduction process ALDH1A1;MSRA;CYP2C8;HMGCR;CYP3A4 GO:0001934| positive regulation of protein phosphorylation AXIN1;ABL1;LYN GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;HCK;CAMK2A GO:0006979| response to oxidative stress MSRA;ABL1 GO:1900034| CAMK2A;CAMK2G GO:0007165| signal transduction LYN;MAP2K1;BCR;AXIN1;LGALS1;SRC GO:0016310| phosphorylation CAMK2G;CDK2;LYN;TRPM7;MAP3K2;ABL1;CAMK2A;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0031295| T cell costimulation LYN;SRC;LGALS1 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP2C8 GO:0043547| positive regulation of GTPase activity BCR;AXIN1;ALDH1A1 GO:0006468| protein phosphorylation MAP2K2;BCR;CAMK2A;SRC;MAP2K1;HCK;ABL1;TRPM7;MAP3K2;CAMK2G;LYN;CDK2 GO:0030154| cell differentiation CAMK2G;CAMK2A;HCK GO:0046777| protein autophosphorylation ABL1;HCK;BCR;SRC;CAMK2A;LYN;CAMK2G;TRPM7 GO:0033146| regulation of intracellular estrogen receptor signaling pathway AXIN1;SRC GO:0043407| negative regulation of MAP kinase activity LYN;HMGCR GO:0006464| protein modification process MSRA;ABL1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway AXIN1;SRC GO:0055085| transmembrane transport ABCB1;TRPM7 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;ABL1;MAP2K2;SRC;MAP2K1 GO:0007257| activation of JUN kinase activity AXIN1;MAP3K2 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CAMK2A;MAP2K1 GO:0006915| apoptotic process LGALS1;AXIN1;ABL1 6421:[DB06616 DB05736] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05736|MIV-701 CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 6422:[DB06616 DB07115] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 6423:[DB06616 DB03477] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response LYN;PTGS2;HCK 6424:[DB06616 DB05295] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05295|Eldecalcitol VDR common genes common pathways GO:0007275| multicellular organismal development VDR;CAMK2G;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;VDR GO:0006816| calcium ion transport CAMK2G;VDR GO:0007165| signal transduction SRC;BCR;MAP2K1;VDR;LYN GO:0010628| positive regulation of gene expression VDR;MAP2K1;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;VDR;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;VDR 6425:[DB06616 DB08566] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 6426:[DB06616 DB11156] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;GPR35 GO:0007165| signal transduction SRC;BCR;MAP2K1;GPR35;CHRM1;LYN GO:0097267| CYP2C8;CYP4A11 GO:0008283| cell proliferation SRC;CHRM1 GO:0006464| protein modification process CHRM1;ABL1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP4A11 GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HCK GO:0007399| nervous system development CAMK2G;CHRM1 GO:0055114| oxidation-reduction process CYP4A11;CYP3A4;CYP2C8 6427:[DB06616 DB03878] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes ABL1 common pathways GO:0030516| regulation of axon extension ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:1905244| ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0038189| ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0043542| endothelial cell migration ABL1 GO:0018108| peptidyl-tyrosine phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;LYN GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:1904528| ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:1900275| ABL1 GO:2000145| regulation of cell motility ABL1 GO:0006897| endocytosis ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:0030155| regulation of cell adhesion ABL1 GO:0030035| microspike assembly ABL1 GO:0048668| collateral sprouting ABL1 GO:0045087| innate immune response SRC;HCK;ABL1;LYN GO:0007155| cell adhesion SRC;HCK;ABL1 GO:2000772| regulation of cellular senescence ABL1 GO:0006281| DNA repair ABL1;CDK2 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN GO:0051882| mitochondrial depolarization ABL1 GO:0038083| LYN;ABL1;SRC;HCK GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:1900042| ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:1901216| ABL1 GO:1904531| ABL1 GO:0010506| regulation of autophagy ABL1 GO:0006909| phagocytosis ABL1;HCK GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0050885| neuromuscular process controlling balance BCR;ABL1 GO:0000278| mitotic cell cycle ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0006914| autophagy ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization ABL1;HCK GO:0006298| mismatch repair ABL1 GO:0042770| signal transduction in response to DNA damage ABL1 GO:1902036| ABL1 GO:0060020| Bergmann glial cell differentiation ABL1;MAP2K1 GO:0038096| SRC;HCK;ABL1;LYN GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0030036| actin cytoskeleton organization BCR;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:1903053| ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0030100| regulation of endocytosis ABL1 GO:0072358| cardiovascular system development ABL1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0001843| neural tube closure ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0048536| spleen development ABL1 GO:0048538| thymus development ABL1;MAP2K1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:0006979| response to oxidative stress ABL1 GO:1900026| ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:1902715| ABL1 GO:1905555| ABL1 GO:0090135| actin filament branching ABL1 GO:1903351| ABL1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0007050| cell cycle arrest MAP2K1;ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:0030182| neuron differentiation MAP2K1;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;LYN GO:0042100| B cell proliferation ABL1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0045184| establishment of protein localization ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0006915| apoptotic process ABL1 GO:0045580| regulation of T cell differentiation ABL1 GO:0002322| B cell proliferation involved in immune response ABL1 GO:0050853| B cell receptor signaling pathway ABL1;LYN GO:0001922| B-1 B cell homeostasis ABL1 GO:1990051| ABL1 GO:1900272| ABL1 GO:0009791| post-embryonic development ABL1 GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;SRC;BCR;ABL1 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0046632| alpha-beta T cell differentiation ABL1 GO:0006464| protein modification process ABL1 6428:[DB06616 DB05131] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05131|TTP889 F9 common genes common pathways GO:0007596| blood coagulation LYN;F9 6429:[DB06616 DB09257] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09257|Gimeracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP2C8;CYP3A4 6430:[DB06616 DB07328] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways GO:0031295| T cell costimulation LYN;DPP4;SRC GO:0043542| endothelial cell migration DPP4;ABL1 GO:0007155| cell adhesion ABL1;SRC;HCK;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;LYN;CDK2;HCK 6431:[DB06616 DB08705] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08705|6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE PIM1 common genes common pathways GO:0016310| phosphorylation PIM1;MAP3K2;CAMK2G;CDK2;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;PIM1;LYN;CDK2;CAMK2G GO:0008283| cell proliferation PIM1;SRC GO:0006915| apoptotic process ABL1;PIM1 GO:0046777| protein autophosphorylation ABL1;HCK;SRC;BCR;LYN;CAMK2G;PIM1 GO:0007049| cell cycle SRC;CDK2;PIM1 GO:0007275| multicellular organismal development CAMK2G;CDK2;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;HCK;SRC GO:0007346| regulation of mitotic cell cycle PIM1;MAP3K2;MAP2K2;MAP2K1 6432:[DB06616 DB03434] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways 6433:[DB06616 DB00429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00429|Carboprost tromethamine PTGER1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGER1;BCR GO:0007165| signal transduction LYN;PTGER1;MAP2K1;BCR;SRC 6434:[DB06616 DB07899] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways 6435:[DB06616 DB09546] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0042493| response to drug ABCB1;SRC;LYN;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0006810| transport SLC6A2;ABCB1 6436:[DB06616 DB08964] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways GO:0007165| signal transduction BCR;PTGER2;SRC;MAP2K1;PTGER3;LYN GO:0042127| regulation of cell proliferation ABL1;PTGER2;SRC GO:0032496| response to lipopolysaccharide PTGER2;BCR 6437:[DB06616 DB00981] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007165| signal transduction CHRNB2;LYN;BCR;CHRNA4;SRC;MAP2K1 GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0006260| DNA replication ACHE;CDK2 GO:0006816| calcium ion transport CAMK2G;CHRNB2;CHRNA4 GO:0006281| DNA repair CHRNA4;ABL1;CDK2 GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ACHE;SRC;HCK;ABL1 6438:[DB06616 DB05507] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05507|VX-765 CASP1;IL1B common genes common pathways GO:0000187| activation of MAPK activity IL1B;MAP2K2;MAP2K1;MAP3K2 GO:0006915| apoptotic process CASP1;ABL1;IL1B GO:0050766| positive regulation of phagocytosis BCR;IL1B GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;IL1B GO:0043407| negative regulation of MAP kinase activity IL1B;LYN GO:0010628| positive regulation of gene expression MAP2K1;SRC;IL1B GO:0030335| positive regulation of cell migration LYN;IL1B GO:0070372| regulation of ERK1 and ERK2 cascade LYN;IL1B GO:0007165| signal transduction IL1B;MAP2K1;BCR;SRC;LYN;CASP1 GO:0050715| positive regulation of cytokine secretion CASP1;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;IL1B;LYN GO:0050900| leukocyte migration IL1B;SRC;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;IL1B;MAP3K2;CDK2 GO:0010506| regulation of autophagy ABL1;CASP1 GO:0000165| MAPKKK cascade CAMK2G;IL1B;MAP2K2;MAP2K1 GO:0019221| cytokine-mediated signaling pathway HCK;IL1B GO:0009743| response to carbohydrate stimulus LYN;IL1B GO:0006954| inflammatory response LYN;IL1B;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;ABL1;CASP1 GO:0032496| response to lipopolysaccharide BCR;IL1B;CASP1 GO:0051882| mitochondrial depolarization CASP1;ABL1 GO:0071260| cellular response to mechanical stimulus CASP1;MAP3K2;IL1B GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;CASP1 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;IL1B;HCK GO:0008284| positive regulation of cell proliferation IL1B;HCK;CDK2;LYN GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;CASP1 GO:0050727| regulation of inflammatory response HCK;CASP1;LYN 6439:[DB06616 DB01133] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01133|Tiludronic acid ATP6V1A;PTPN1 common genes common pathways GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1;PTPN1 GO:0006810| transport ABCB1;ATP6V1A GO:0030100| regulation of endocytosis ABL1;PTPN1 GO:0007257| activation of JUN kinase activity PTPN1;MAP3K2 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;PTPN1;LYN GO:0006470| protein dephosphorylation PTPN1;CAMK2G GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway PTPN1;LYN GO:0043407| negative regulation of MAP kinase activity LYN;PTPN1 6440:[DB06616 DB02134] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 6441:[DB06616 DB07846] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways GO:0006260| DNA replication ACHE;CDK2 GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ABL1;HCK;SRC;ACHE GO:0008283| cell proliferation SRC;ACHE 6442:[DB06616 DB06550] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06550|Bivatuzumab CD44 common genes common pathways GO:0098609| SRC;CD44 GO:0060333| interferon-gamma-mediated signaling pathway CD44;CAMK2G;HCK GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;SRC;MAP2K2;CD44 GO:0043066| negative regulation of apoptotic process HCK;SRC;CD44 GO:0007155| cell adhesion ABL1;SRC;HCK;CD44 GO:0050900| leukocyte migration SRC;CD44;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CD44;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;CD44;SRC;ABL1 6443:[DB06616 DB05804] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0060065| uterus development SRC;CYP19A1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2C8 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS2;LYN;HCK GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;PTGS2;CYP3A7;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0042493| response to drug SRC;ABCB1;PTGS2;LYN GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0006810| transport ABCB11;ABCB1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0008202| steroid metabolic process CYP2C8;CYP3A7;CYP3A4 GO:0034605| cellular response to heat PTGS2;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance PTGS2;CDK2 GO:0055085| transmembrane transport SLCO1A2;SLCO1B1;SLC22A8;ABCB11;SLCO1B3;ABCB1;SLCO2B1;SLC10A6 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0009636| response to toxin SLC22A8;LYN GO:0002933| CYP3A4;CYP3A7;CYP2C8 6444:[DB06616 DB04144] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways GO:0043066| negative regulation of apoptotic process MDM2;SRC;HCK GO:0008284| positive regulation of cell proliferation LYN;CDK2;MDM2;HCK GO:1901796| MDM2;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MDM2;CDK2 GO:0007507| heart development MAP2K1;MDM2 GO:0045931| positive regulation of mitotic cell cycle ABL1;MDM2 GO:0016032| viral reproduction SRC;HCK;MDM2;LYN GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;MDM2 GO:0042493| response to drug ABCB1;SRC;MDM2;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;SRC GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest MDM2;CDK2 GO:0031648| protein destabilization SRC;MDM2 GO:0071456| cellular response to hypoxia SRC;MDM2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;MDM2 GO:0045892| negative regulation of transcription, DNA-dependent MDM2;SRC GO:0071375| cellular response to peptide hormone stimulus SRC;MDM2 GO:0070301| cellular response to hydrogen peroxide MDM2;ABL1 GO:0009636| response to toxin MDM2;LYN GO:0045184| establishment of protein localization MDM2;ABL1 6445:[DB06616 DB07430] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;MAPKAPK2;HCK;BCR;SRC GO:0000187| activation of MAPK activity MAP3K2;MAP2K2;MAP2K1;MAPKAPK2 GO:1900034| CAMK2G;MAPKAPK2 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;MAPKAPK2;MAP2K2;BCR;SRC GO:0016310| phosphorylation MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;MAPKAPK2;HCK;BCR;MAP2K2;SRC;ABL1 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;MAPKAPK2;CAMK2G GO:0006954| inflammatory response LYN;HCK;MAPKAPK2 GO:0006974| response to DNA damage stimulus ABL1;MAPKAPK2;LYN;CDK2 GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC;MAPKAPK2 GO:0048010| vascular endothelial growth factor receptor signaling pathway MAPKAPK2;SRC GO:0007265| Ras protein signal transduction MAPKAPK2;CDK2 GO:0032496| response to lipopolysaccharide BCR;MAPKAPK2 6446:[DB06616 DB03639] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;DHPS;LYN;CDK2 6447:[DB06616 DB07563] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07563|1-{7-cyclohexyl-6-[4-(4-methylpiperazin-1-yl)benzyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 6448:[DB06616 DB11133] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0014070| response to organic cyclic compound LYN;PPARG;PTGS2;SREBF1 GO:0032868| response to insulin stimulus LYN;PPARA GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG;CDK2 GO:0008202| steroid metabolic process CYP3A4;SREBF1;CYP2C8 GO:0043434| response to peptide hormone stimulus LYN;SREBF1 GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0032869| cellular response to insulin stimulus SREBF1;SRC;PPARG GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0007165| signal transduction LYN;PPARG;MAP2K1;SRC;BCR GO:0070542| response to fatty acid PTGS2;SREBF1;SRC GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA;SREBF1;ABL1 GO:0042493| response to drug PTGS2;PPARG;LYN;SRC;SREBF1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;SREBF1;MAP3K2;CDK2;PPARG;PPARA GO:0055114| oxidation-reduction process PTGS2;CYP3A4;ALOX5;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006954| inflammatory response ALOX5;HCK;PTGS2;LYN GO:0050728| negative regulation of inflammatory response PPARA;BCR GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC GO:0008284| positive regulation of cell proliferation PTGS2;LYN;CDK2;HCK GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG;SRC;ABL1 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0071398| cellular response to fatty acid SREBF1;SRC GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0045087| innate immune response LYN;PPARG;HCK;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PPARA;CDK2;SREBF1 GO:0007507| heart development MAP2K1;PPARG;PPARA GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PPARA;PPARG;PTGS2;SREBF1 GO:0051974| negative regulation of telomerase activity SRC;PPARG 6449:[DB06616 DB02376] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02376|D-gluconhydroximo-1,5-lactam LCT common genes common pathways 6450:[DB06616 DB01325] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0071498| cellular response to fluid shear stress SRC;CA2 GO:0006810| transport SLC12A2;SLC12A1;ABCB1;SLC12A3 GO:0006813| potassium ion transport SLC12A2;CDK2;SLC12A1 GO:0055085| transmembrane transport SLC12A2;ABCB1;SLC12A3;SLC12A1 GO:0010033| response to organic substance CA2;CDK2 6451:[DB06616 DB01353] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;CHRNA7 GO:0006281| DNA repair CDK2;CHRNA4;ABL1 GO:0006816| calcium ion transport CAMK2G;CHRNA4;CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1;LYN GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0007165| signal transduction GABRA5;GABRA6;LYN;BCR;SRC;GRIA2;CHRNA4;MAP2K1;CHRNA7 GO:0007420| brain development BCR;GABRA5 GO:0007417| central nervous system development SRC;LYN;GABRA4 GO:0006810| transport ABCB1;GABRA3;GABRA5;GRIK2;GABRA6;GABRA4;GABRA1 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;CHRNA7 GO:0000187| activation of MAPK activity MAP3K2;MAP2K1;MAP2K2;CHRNA7 6452:[DB06616 DB07845] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07845|2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide MAPK8 common genes common pathways GO:0038095| LYN;MAPK8 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1;MAPK8 GO:0034614| cellular response to reactive oxygen species SRC;MAPK8 GO:0010628| positive regulation of gene expression MAPK8;MAP2K1;SRC GO:0016310| phosphorylation MAPK8;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAPK8;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;MAPK8 GO:0043066| negative regulation of apoptotic process HCK;MAPK8;SRC GO:0071222| cellular response to lipopolysaccharide MAPK8;BCR;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;MAPK8;CAMK2G;CDK2 GO:0043065| positive regulation of apoptotic process MAPK8;SRC;ABL1 GO:0071260| cellular response to mechanical stimulus MAPK8;MAP3K2 6453:[DB06616 DB04537] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;WARS GO:0010628| positive regulation of gene expression MAP2K1;SRC;WARS GO:0001933| negative regulation of protein phosphorylation WARS;LYN 6454:[DB06616 DB13934] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13934|Ligandrol AR common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0010628| positive regulation of gene expression AR;MAP2K1;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC GO:0007165| signal transduction AR;MAP2K1;SRC;BCR;LYN GO:0006810| transport AR;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;AR;MAP3K2;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;AR;HCK GO:0051259| protein oligomerization AR;CAMK2G 6455:[DB06616 DB04985] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04985|Tigapotide RPSA common genes common pathways GO:0007155| cell adhesion RPSA;SRC;HCK;ABL1 GO:0016032| viral reproduction LYN;RPSA;HCK;SRC 6456:[DB06616 DB05141] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05141|LY2181308 BIRC5 common genes common pathways GO:0051301| cell division CDK2;BIRC5 GO:0007346| regulation of mitotic cell cycle BIRC5;MAP2K1;MAP2K2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;BIRC5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process BIRC5;SRC GO:0000278| mitotic cell cycle ABL1;BIRC5 GO:0043066| negative regulation of apoptotic process SRC;BIRC5;HCK GO:0008284| positive regulation of cell proliferation BIRC5;HCK;CDK2;LYN GO:0042981| regulation of apoptotic process BIRC5;MAP2K1;MAP2K2;MAP3K2 GO:0045931| positive regulation of mitotic cell cycle ABL1;BIRC5 GO:0007049| cell cycle SRC;BIRC5;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;BIRC5 GO:0006915| apoptotic process BIRC5;ABL1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;BIRC5;CDK2 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;MAP2K1;BIRC5;HCK;MAP2K2;BCR;SRC 6457:[DB06616 DB00395] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00395|Carisoprodol GABRA1;GABRB2;GABRG2;CYP2C19 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A4 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C19 GO:0006810| transport ABCB1;GABRA1;GABRB2;GABRG2 GO:0009791| post-embryonic development GABRG2;ABL1 6458:[DB06616 DB00058] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;ELANE GO:0050728| negative regulation of inflammatory response BCR;ELANE GO:0050900| leukocyte migration LYN;ELANE;SRC GO:0006909| phagocytosis ABL1;HCK;ELANE GO:0000122| negative regulation of transcription from RNA polymerase II promoter ELANE;CDK2 GO:0032496| response to lipopolysaccharide BCR;ELANE 6459:[DB06616 DB04398] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A1;SLCO2B1;ABCB1;SLC16A3;SLC16A7;SLC16A10;SLCO2A1 GO:0050900| leukocyte migration SLC16A3;LYN;SRC;SLC16A1 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 6460:[DB06616 DB06883] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06883|1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea SRC common genes SRC common pathways GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response LYN;HCK;SRC;ABL1 GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC GO:0071398| cellular response to fatty acid SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0060065| uterus development SRC GO:0086098| SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN GO:0042127| regulation of cell proliferation ABL1;SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0038096| LYN;HCK;SRC;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0038128| SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0051602| response to electrical stimulus SRC GO:2000811| negative regulation of anoikis SRC GO:0016032| viral reproduction LYN;SRC;HCK GO:0050900| leukocyte migration SRC;LYN GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0034332| adherens junction organization SRC GO:0042493| response to drug SRC;ABCB1;LYN GO:0038083| LYN;ABL1;HCK;SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;MAP3K2 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN GO:2000386| positive regulation of ovarian follicle development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0032463| negative regulation of protein homooligomerization SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0071456| cellular response to hypoxia SRC GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2 GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle CDK2;SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0046777| protein autophosphorylation ABL1;SRC;BCR;HCK;CAMK2G;LYN GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0034614| cellular response to reactive oxygen species SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1 GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC 6461:[DB06616 DB13174] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2D6;ALOX5;CYP3A43;CYP2C9;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1H3;NR1H2 GO:0042493| response to drug CYP1A2;CYP2E1;LYN;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP2C9;CYP3A4 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NR1H2 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;NR1H3;MAP2K1;CDK2;MAP3K2;NR1H2 GO:0050728| negative regulation of inflammatory response NR1H3;BCR GO:0006954| inflammatory response LYN;HCK;ALOX5 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP1A2;CYP3A5;CYP2D6 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2C9;CYP2E1;CYP3A4;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H3;CDK2;NR1H2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2D6 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;NR1H3 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C8;CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2C8 GO:0036378| CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0002933| CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1H2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010628| positive regulation of gene expression NR1H2;MAP2K1;SRC GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A5;CYP3A4;CYP2C9;CYP2E1;CYP3A7;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP2C9;CYP3A4 GO:0097267| CYP1A2;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A5 6462:[DB06616 DB00100] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00100|Coagulation Factor IX (Recombinant) F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0032956| regulation of actin cytoskeleton organization LRP1;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;F2 GO:1900182| F2;SRC GO:0051222| positive regulation of protein transport SRC;LRP1 GO:0009725| response to hormone stimulus F7;LYN GO:0030335| positive regulation of cell migration F10;LYN;F7 GO:0030168| platelet activation LYN;F8;SRC;F2 GO:0006464| protein modification process ABL1;GGCX GO:0014070| response to organic cyclic compound LYN;F7 GO:0008283| cell proliferation LRP1;SRC GO:0007596| blood coagulation F7;F2;F11;GGCX;LYN;F10;F8 GO:0006897| endocytosis LRP1;ABL1 GO:0008284| positive regulation of cell proliferation HCK;F2;LYN;CDK2 GO:0002576| platelet degranulation LYN;F8 GO:0006629| lipid metabolic process LRP1;CYP3A4 GO:0008360| regulation of cell shape F2;HCK GO:0045056| transcytosis SRC;LRP1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC GO:0007275| multicellular organismal development CAMK2G;CDK2;LRP1;F2 GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC;F7 GO:0031667| response to nutrient levels SRC;F7 GO:0006909| phagocytosis LRP1;HCK;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;F8 GO:0001934| positive regulation of protein phosphorylation LYN;F2;ABL1 GO:0050900| leukocyte migration LYN;F2;SRC 6463:[DB06616 DB07031] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07031|3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid RARG common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;RARG GO:0010628| positive regulation of gene expression MAP2K1;SRC;RARG GO:0001843| neural tube closure RARG;ABL1 GO:0060324| face development RARG;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent RARG;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;CDK2 GO:0071300| cellular response to retinoic acid LYN;RARG GO:0043066| negative regulation of apoptotic process RARG;SRC;HCK GO:0043065| positive regulation of apoptotic process SRC;RARG;ABL1 GO:0008284| positive regulation of cell proliferation RARG;HCK;LYN;CDK2 6464:[DB06616 DB11359] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11359|Guaiacol ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation ALB;LYN 6465:[DB06616 DB07161] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways GO:0006915| apoptotic process JAK2;ABL1 GO:0016477| cell migration SRC;JAK2 GO:0007596| blood coagulation LYN;JAK2 GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway LYN;JAK2 GO:0008285| negative regulation of cell proliferation JAK2;LYN;MAP2K1 GO:0006928| cellular component movement MAP2K1;JAK2 GO:0046777| protein autophosphorylation ABL1;HCK;BCR;SRC;LYN;CAMK2G;JAK2 GO:0000186| activation of MAPKK activity JAK2;MAP3K2 GO:0030154| cell differentiation HCK;JAK2;CAMK2G GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;JAK2;CDK2;LYN;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration JAK2;ABL1 GO:0030335| positive regulation of cell migration LYN;JAK2 GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;JAK2;MAP3K2 GO:0007165| signal transduction JAK2;LYN;SRC;BCR;MAP2K1 GO:0006979| response to oxidative stress JAK2;ABL1 GO:0002376| immune system process LYN;JAK2;HCK;SRC GO:0022408| negative regulation of cell-cell adhesion JAK2;ABL1 GO:0060333| interferon-gamma-mediated signaling pathway HCK;JAK2;CAMK2G GO:0038083| HCK;SRC;ABL1;JAK2;LYN GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CAMK2G;JAK2 GO:0030218| erythrocyte differentiation LYN;JAK2 GO:0002250| adaptive immune response LYN;JAK2 GO:0019221| cytokine-mediated signaling pathway JAK2;HCK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;JAK2;ABL1;SRC GO:0007498| mesoderm development JAK2;HCK GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;JAK2 GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;LYN;JAK2 GO:0048008| platelet-derived growth factor receptor signaling pathway JAK2;BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation JAK2;ABL1;SRC GO:0032496| response to lipopolysaccharide BCR;JAK2 GO:0045597| positive regulation of cell differentiation JAK2;MAP2K1 GO:0045087| innate immune response SRC;HCK;ABL1;JAK2;LYN GO:0042981| regulation of apoptotic process JAK2;MAP3K2;MAP2K2;MAP2K1 GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G;JAK2 GO:0043065| positive regulation of apoptotic process JAK2;ABL1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;JAK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;JAK2;HCK 6466:[DB06616 DB03777] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03777|Rbt205 Inhibitor PIM1;PDPK1;PRKCI common genes common pathways GO:0006915| apoptotic process ABL1;PIM1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;PDPK1;MAP2K1 GO:0016477| cell migration SRC;PRKCI;PDPK1 GO:0008283| cell proliferation PIM1;SRC GO:0038095| PDPK1;LYN GO:0007049| cell cycle PIM1;CDK2;SRC GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;PIM1;CAMK2G;PDPK1;LYN GO:0030168| platelet activation LYN;PDPK1;SRC GO:0032869| cellular response to insulin stimulus PDPK1;SRC;PRKCI GO:0006468| protein phosphorylation PIM1;MAP3K2;CAMK2G;LYN;CDK2;PDPK1;SRC;PRKCI;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0043434| response to peptide hormone stimulus LYN;PRKCI GO:0016310| phosphorylation CAMK2G;LYN;CDK2;PDPK1;PIM1;MAP3K2;ABL1;SRC;PRKCI;MAP2K2;BCR;HCK;MAP2K1 GO:0031295| T cell costimulation SRC;LYN;PDPK1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0070555| response to interleukin-1 SRC;PRKCI GO:0007173| epidermal growth factor receptor signaling pathway PDPK1;ABL1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;PDPK1 GO:0007346| regulation of mitotic cell cycle PIM1;MAP3K2;MAP2K2;MAP2K1 GO:0030036| actin cytoskeleton organization PDPK1;BCR;ABL1 GO:0010976| positive regulation of neuron projection development PRKCI;LYN GO:0007275| multicellular organismal development PIM1;CAMK2G;CDK2 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;PDPK1 GO:0032148| activation of protein kinase B activity SRC;PDPK1 GO:0043066| negative regulation of apoptotic process PIM1;HCK;PRKCI;SRC GO:0035556| intracellular signal transduction LYN;PDPK1;CAMK2G;BCR;SRC;PRKCI GO:0060252| positive regulation of glial cell proliferation PRKCI;LYN GO:0018105| peptidyl-serine phosphorylation PDPK1;CDK2;CAMK2G;PRKCI;SRC GO:0043304| regulation of mast cell degranulation PDPK1;LYN 6467:[DB06616 DB03677] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways GO:0009636| response to toxin EPHX2;LYN GO:0010628| positive regulation of gene expression EPHX2;MAP2K1;SRC GO:0017144| drug metabolic process CYP2C8;CYP3A4;EPHX2 GO:0006954| inflammatory response HCK;LYN;EPHX2 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process CYP2C8;EPHX2;CYP3A4 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 6468:[DB06616 DB11738] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11738|Rilmenidine ADRA2A common genes common pathways GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;ADRA2A GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0007165| signal transduction MAP2K1;SRC;BCR;ADRA2A;LYN GO:0030168| platelet activation LYN;ADRA2A;SRC GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0006928| cellular component movement ADRA2A;MAP2K1 6469:[DB06616 DB08009] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways GO:0035556| intracellular signal transduction CAMK2G;LYN;CAMK1G;BCR;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CAMK1G;CAMK2G;CDK2 GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;CAMK1G;MAP3K2 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;CAMK1G;MAP3K2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CAMK1G 6470:[DB06616 DB03886] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03886|Biopterin SPR;PTS;DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;SPR;CYP2C8 GO:0007417| central nervous system development LYN;PTS;SRC 6471:[DB06616 DB02530] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;GATM GO:0055085| transmembrane transport ABCB1;SLC36A1 GO:0007165| signal transduction GABBR2;MAP2K1;SRC;BCR;LYN;GABBR1 6472:[DB06616 DB05879] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05879|AME-527 TNF common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0042127| regulation of cell proliferation TNF;SRC;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0071222| cellular response to lipopolysaccharide TNF;BCR;SRC;ABL1 GO:0009615| response to virus TNF;SRC GO:0050727| regulation of inflammatory response HCK;TNF;LYN GO:0043065| positive regulation of apoptotic process TNF;SRC;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN;TNF GO:0050900| leukocyte migration TNF;LYN;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;TNF;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TNF GO:0045893| positive regulation of transcription, DNA-dependent CDK2;TNF;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0006954| inflammatory response HCK;TNF;LYN GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0051222| positive regulation of protein transport TNF;SRC GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ABL1;SRC;MAP2K2;MAP2K1 GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0000187| activation of MAPK activity TNF;MAP3K2;MAP2K1;MAP2K2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0045892| negative regulation of transcription, DNA-dependent TNF;SRC GO:0010033| response to organic substance CDK2;TNF GO:0010628| positive regulation of gene expression TNF;SRC;MAP2K1 6473:[DB06616 DB11186] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;OPRK1;SRC;BCR GO:0007399| nervous system development SIGMAR1;CAMK2G GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 GO:0006813| potassium ion transport KCNH2;CDK2 GO:0007165| signal transduction LYN;OPRM1;OPRK1;SRC;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0008285| negative regulation of cell proliferation OPRM1;LYN;MAP2K1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0055085| transmembrane transport KCNH2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ABL1;SRC;MAP2K2;MAP2K1 6474:[DB06616 DB13877] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13877|Iniparib PARP1 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC;PARP1 GO:0006915| apoptotic process PARP1;ABL1 GO:0032869| cellular response to insulin stimulus PARP1;SRC GO:1900182| PARP1;SRC GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:1901216| ABL1;PARP1 GO:0034599| cellular response to oxidative stress ABL1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 GO:0006974| response to DNA damage stimulus LYN;CDK2;PARP1;ABL1 GO:0006281| DNA repair ABL1;CDK2;PARP1 6475:[DB06616 DB04476] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04476|Trencam-3,2-Hopo LCN2 common genes common pathways GO:0006915| apoptotic process ABL1;LCN2 GO:0002376| immune system process LYN;HCK;SRC;LCN2 GO:0045087| innate immune response LYN;ABL1;HCK;LCN2;SRC 6476:[DB06616 DB08325] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;MERTK;ABL1;LYN GO:0008360| regulation of cell shape CSNK1G1;HCK GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;CSNK1G1;SRC GO:0006897| endocytosis CSNK1G1;ABL1 GO:0050900| leukocyte migration LYN;MERTK;SRC GO:0006909| phagocytosis HCK;MERTK;ABL1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC;MERTK GO:0006468| protein phosphorylation ABL1;MAP2K1;MERTK;HCK;BCR;MAP2K2;CSNK1G1;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0030168| platelet activation LYN;MERTK;SRC GO:0016310| phosphorylation BCR;CSNK1G1;MAP2K2;SRC;MAP2K1;MERTK;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0050766| positive regulation of phagocytosis BCR;MERTK 6477:[DB06616 DB07449] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PADI4 GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PADI4 GO:0006464| protein modification process ABL1;PADI4 GO:0002376| immune system process LYN;PADI4;HCK;SRC 6478:[DB06616 DB01279] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01279|Galsulfase PLIN3 common genes common pathways 6479:[DB06616 DB00391] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00391|Sulpiride DRD2;DRD3;CA2;CA3;BCHE common genes common pathways GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;DRD2;BCR GO:0008284| positive regulation of cell proliferation CDK2;LYN;DRD3;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DRD3 GO:0048678| response to axon injury LYN;DRD2 GO:0071498| cellular response to fluid shear stress CA2;SRC GO:0042493| response to drug ABCB1;SRC;DRD2;DRD3;LYN;BCHE GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0006979| response to oxidative stress ABL1;CA3 GO:0030900| forebrain development DRD2;SRC GO:0007165| signal transduction BCR;DRD2;SRC;MAP2K1;LYN;DRD3 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0010033| response to organic substance CDK2;CA2 GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;BCHE;LYN GO:0009636| response to toxin DRD2;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;DRD2;MAP2K2;MAP2K1;ABL1 6480:[DB06616 DB00388] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1B;ABL1;ADRA1D GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0007165| signal transduction ADRA1D;LYN;MAP2K1;ADRA1A;SRC;BCR;ADRA1B GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;ADRA1A;SRC;MAP2K1;ABL1 GO:0006915| apoptotic process ABL1;ADRA1A GO:0008283| cell proliferation ADRA1B;SRC;ADRA1D GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0007275| multicellular organismal development CAMK2G;CDK2;ADRA1D;ADRA1B GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;ADRA1D GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0035556| intracellular signal transduction CAMK2G;LYN;ADRA1B;SRC;ADRA1A;BCR GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2;MAOA GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;LYN;SRC;ADRA1A;ABCB1 6481:[DB06616 DB07933] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07933|Erteberel ESR2;ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction LYN;ESR1;MAP2K1;BCR;SRC;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;ESR1;MAP2K1;MAP2K2;SRC;ESR2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1;ESR2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 6482:[DB06616 DB07283] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07283|9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid FABP4 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent SRC;FABP4 GO:0050727| regulation of inflammatory response LYN;HCK;FABP4 6483:[DB06616 DB00284] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways GO:0050885| neuromuscular process controlling balance ABL1;BCR;GAA 6484:[DB06616 DB01401] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0034605| cellular response to heat LYN;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1;ABL1 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK 6485:[DB06616 DB08739] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08739|2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dione PREP common genes common pathways 6486:[DB06616 DB09085] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09085|Tetracaine RYR1;RYR2 common genes common pathways GO:0055085| transmembrane transport ABCB1;RYR2;RYR1 GO:0006816| calcium ion transport RYR1;RYR2;CAMK2G GO:0007275| multicellular organismal development RYR1;RYR2;CDK2;CAMK2G 6487:[DB06616 DB06560] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06560|Pascolizumab IL4 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;IL4 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;IL4;CDK2 GO:0097028| dendritic cell differentiation IL4;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC;IL4 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;IL4 6488:[DB06616 DB05889] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes ABCB1 common pathways GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0007155| cell adhesion ABL1;SRC;HCK;CD22 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug LYN;SRC;ABCB1 6489:[DB06616 DB05367] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05367|Actelion-1 EDNRA common genes common pathways GO:0007165| signal transduction LYN;EDNRA;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;ABL1 GO:0008283| cell proliferation EDNRA;SRC GO:0007507| heart development EDNRA;MAP2K1 6490:[DB06616 DB01004] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01004|Ganciclovir SLC22A1;SLC22A6;SLC22A8;SLC22A7;SLC47A1;SLC47A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;SLC47A2;SLC47A1;ABCB1 GO:0055085| transmembrane transport SLC47A2;SLC22A7;ABCB1;SLC47A1;SLC22A8;SLC22A6;SLC22A1 GO:0009636| response to toxin LYN;SLC22A8 6491:[DB06616 DB08499] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways GO:0010033| response to organic substance CDK2;CASP3 GO:0043200| response to amino acid stimulus LYN;CASP3 GO:0014070| response to organic cyclic compound LYN;CASP3 GO:0030182| neuron differentiation ABL1;CASP3;MAP2K1 GO:0030216| keratinocyte differentiation CASP3;MAP2K1 GO:0006915| apoptotic process CASP3;ABL1 GO:0030889| negative regulation of B cell proliferation LYN;CASP3 GO:0001782| B cell homeostasis CASP3;LYN GO:0030218| erythrocyte differentiation LYN;CASP3 GO:0042493| response to drug SRC;ABCB1;CASP3;LYN GO:0048011| nerve growth factor receptor signaling pathway SRC;CASP3 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;CASP3 GO:0043066| negative regulation of apoptotic process SRC;HCK;CASP3 GO:0043065| positive regulation of apoptotic process ABL1;SRC;CASP3 GO:0042542| response to hydrogen peroxide CASP3;SRC GO:0006974| response to DNA damage stimulus ABL1;CASP3;CDK2;LYN GO:0007507| heart development CASP3;MAP2K1 GO:0032496| response to lipopolysaccharide CASP3;BCR 6492:[DB06616 DB01013] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction MAP2K1;SRC;BCR;NR3C1;LYN GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0010033| response to organic substance CDK2;CYP1A1 GO:0008283| cell proliferation CYP1A1;SRC GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0009636| response to toxin LYN;CYP1A1 GO:0036378| CYP3A4 GO:0006915| apoptotic process ABL1;NR3C1 GO:0009615| response to virus CYP1A1;SRC GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0032496| response to lipopolysaccharide BCR;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0051301| cell division NR3C1;CDK2 GO:0042493| response to drug SRC;ABCB1;CYP1A1;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A1 6493:[DB06616 DB00427] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00427|Triprolidine HRH1 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;HRH1 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0006954| inflammatory response HCK;LYN;HRH1 6494:[DB06616 DB04369] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04369|1,3,2-Dioxaborolan-2-Ol PRSS3 common genes common pathways GO:0043542| endothelial cell migration ABL1;PRSS3 6495:[DB06616 DB12020] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways GO:0017144| drug metabolic process CYP2C8;UGT1A1;UGT1A4;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0010033| response to organic substance UGT1A1;CDK2 GO:0014070| response to organic cyclic compound UGT1A1;LYN GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide BCR;UGT1A1 GO:0042493| response to drug SRC;ABCB1;UGT1A1;LYN 6496:[DB06616 DB06235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;LYN;ABCB1;SRC GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process UGT2B7;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;UGT1A9;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT2B7;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A9;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 6497:[DB06616 DB04971] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG;ABL1 GO:0042493| response to drug ABCB1;SRC;PPARG;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2;PPARG;PPARA GO:0050728| negative regulation of inflammatory response PPARA;BCR GO:0043065| positive regulation of apoptotic process PPARG;SRC;ABL1 GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;CDK2 GO:0045087| innate immune response PPARG;LYN;SRC;HCK;ABL1 GO:0007507| heart development MAP2K1;PPARA;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARA;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0014070| response to organic cyclic compound PPARG;LYN GO:0032868| response to insulin stimulus LYN;PPARA GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0010033| response to organic substance CDK2;PPARG GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0007165| signal transduction PPARG;LYN;SRC;BCR;MAP2K1 6498:[DB06616 DB00337] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes CYP3A4 common pathways GO:0009791| post-embryonic development ABL1;MTOR GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;MTOR;CAMK2G;LYN GO:0010628| positive regulation of gene expression MTOR;MAP2K1;SRC GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0043200| response to amino acid stimulus MTOR;LYN GO:0051496| positive regulation of stress fiber assembly ABL1;MTOR GO:0002933| CYP3A4;CYP2C8 GO:0032868| response to insulin stimulus LYN;MTOR GO:0036378| CYP3A4 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MTOR;MAP2K1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;FKBP1A GO:0032956| regulation of actin cytoskeleton organization MTOR;ABL1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:1900034| MTOR;CAMK2G GO:0007165| signal transduction MTOR;LYN;BCR;SRC;MAP2K1 GO:0007420| brain development BCR;MTOR GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0007050| cell cycle arrest MTOR;MAP2K1;ABL1 GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;MAP3K2;MTOR;CAMK2G;CDK2;LYN GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0006468| protein phosphorylation MAP3K2;MTOR;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0071456| cellular response to hypoxia SRC;MTOR GO:0010976| positive regulation of neuron projection development MTOR;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;LYN;SRC;ABL1 GO:0019221| cytokine-mediated signaling pathway FKBP1A;HCK GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;SRC GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:1901216| MTOR;ABL1 GO:0008209| androgen metabolic process CYP3A4 GO:0001934| positive regulation of protein phosphorylation LYN;MTOR;ABL1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0060252| positive regulation of glial cell proliferation MTOR;LYN GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;MTOR GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0032148| activation of protein kinase B activity SRC;MTOR GO:0006281| DNA repair ABL1;CDK2;MTOR GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0001932| regulation of protein phosphorylation MTOR;LYN;MAP2K1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0030838| positive regulation of actin filament polymerization MTOR;HCK GO:0001933| negative regulation of protein phosphorylation FKBP1A;MTOR;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;FKBP1A GO:0042737| drug catabolic process CYP3A4 6499:[DB06616 DB05092] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05092|CDP323 ITGA4 common genes common pathways GO:0007229| integrin-mediated signaling pathway ABL1;ITGA4;SRC;HCK GO:0007155| cell adhesion ABL1;ITGA4;SRC;HCK GO:0050900| leukocyte migration LYN;ITGA4;SRC GO:0034446| substrate adhesion-dependent cell spreading ITGA4;SRC;ABL1 6500:[DB06616 DB01340] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug LYN;ABCB1;SRC GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport SLC15A1;SLC15A2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 6501:[DB06616 DB05297] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0043066| negative regulation of apoptotic process BCL2;HCK;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;BCL2 GO:0051726| regulation of cell cycle BCL2;BCR;SRC;ABL1 GO:0042542| response to hydrogen peroxide SRC;BCL2 GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;BCL2;SRC GO:0006974| response to DNA damage stimulus CDK2;LYN;BCL2;ABL1 GO:0042981| regulation of apoptotic process BCL2;MAP3K2;MAP2K1;MAP2K2 GO:0010506| regulation of autophagy ABL1;BCL2 GO:0042493| response to drug LYN;BCL2;ABCB1;SRC GO:0051902| negative regulation of mitochondrial depolarization BCL2;SRC GO:2000811| negative regulation of anoikis SRC;BCL2 GO:0001782| B cell homeostasis LYN;BCL2 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway BCL2;SRC GO:0051924| regulation of calcium ion transport CAMK2G;BCL2 GO:0098609| SRC;BCL2 GO:0045930| negative regulation of mitotic cell cycle BCL2;ABL1 GO:0071456| cellular response to hypoxia SRC;BCL2 GO:0006979| response to oxidative stress BCL2;ABL1 GO:0048536| spleen development ABL1;BCL2 GO:0048538| thymus development BCL2;ABL1;MAP2K1 GO:0030097| hemopoiesis BCL2;LYN GO:0003014| renal system process BCL2;BCR GO:0006470| protein dephosphorylation CAMK2G;BCL2 GO:0009636| response to toxin BCL2;LYN GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;BCR GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;BCL2 GO:0008283| cell proliferation SRC;BCL2 GO:0006915| apoptotic process BCL2;ABL1 GO:0042100| B cell proliferation BCL2;ABL1 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;BCL2;CAMK2G GO:0009791| post-embryonic development BCL2;ABL1 GO:0030336| negative regulation of cell migration BCR;BCL2 GO:0050853| B cell receptor signaling pathway LYN;BCL2;ABL1 GO:0008285| negative regulation of cell proliferation BCL2;LYN;MAP2K1 GO:0014911| positive regulation of smooth muscle cell migration SRC;BCL2 6502:[DB06616 DB03738] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 6503:[DB06616 DB08890] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08890|Linaclotide GUCY2C common genes common pathways GO:0042127| regulation of cell proliferation GUCY2C;SRC;ABL1 GO:0035556| intracellular signal transduction LYN;CAMK2G;GUCY2C;SRC;BCR GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;GUCY2C;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0009636| response to toxin LYN;GUCY2C 6504:[DB06616 DB11134] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11134|Cupric oxide ALB;CP common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CP GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC 6505:[DB06616 DB07285] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process MMP9;HCK;SRC GO:0043065| positive regulation of apoptotic process MMP9;SRC;ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;MMP9;ABL1 GO:0050900| leukocyte migration LYN;MMP9;SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;MMP9 GO:0030335| positive regulation of cell migration MMP9;LYN GO:0034614| cellular response to reactive oxygen species MMP9;SRC GO:0048013| ephrin receptor signaling pathway MMP9;LYN;SRC 6506:[DB06616 DB03390] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways 6507:[DB06616 DB07419] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07419|S-23 AR common genes common pathways GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0008284| positive regulation of cell proliferation AR;HCK;CDK2;LYN GO:0051259| protein oligomerization CAMK2G;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;SRC;MAP2K2;MAP2K1;AR GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;AR GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:0010628| positive regulation of gene expression AR;SRC;MAP2K1 GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC 6508:[DB06616 DB04689] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction PPARG;LYN;BCR;SRC;MAP2K1 GO:0014070| response to organic cyclic compound LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0007507| heart development PPARG;MAP2K1 GO:0045087| innate immune response PPARG;LYN;ABL1;SRC;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;CDK2;PPARG;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 6509:[DB06616 DB04577] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;SRC;HCK;ABL1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0043542| endothelial cell migration DPP4;ABL1 GO:0031295| T cell costimulation DPP4;LYN;SRC 6510:[DB06616 DB04099] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04099|Deamido-Nad+ nadE;NMNAT1;nadD;NMNAT3;nadE;nadE common genes common pathways 6511:[DB06616 DB07069] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 6512:[DB06616 DB07728] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAPKAPK2;MAPKAPK3;MAP3K2 GO:0046777| protein autophosphorylation MAPKAPK3;LYN;CAMK2G;MAPKAPK2;HCK;SRC;BCR;ABL1 GO:0006468| protein phosphorylation MAP3K2;MAPKAPK3;LYN;CDK2;CAMK2G;MAP2K1;HCK;MAPKAPK2;MAP2K2;BCR;SRC;ABL1 GO:0016310| phosphorylation MAP3K2;MAPKAPK3;LYN;CDK2;CAMK2G;MAPKAPK2;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0007165| signal transduction MAP2K1;BCR;SRC;MAPKAPK3;LYN GO:1900034| CAMK2G;MAPKAPK2 GO:0000165| MAPKKK cascade MAPKAPK3;CAMK2G;MAP2K2;MAPKAPK2;MAP2K1 GO:0006954| inflammatory response MAPKAPK2;HCK;LYN GO:0007265| Ras protein signal transduction CDK2;MAPKAPK3;MAPKAPK2 GO:0032496| response to lipopolysaccharide BCR;MAPKAPK2;MAPKAPK3 GO:0006974| response to DNA damage stimulus ABL1;MAPKAPK2;LYN;CDK2 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;MAPKAPK3;MAPKAPK2;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;MAPKAPK2;MAPKAPK3 6513:[DB06616 DB00509] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent SRC;THRB;THRA GO:0055085| transmembrane transport SLCO4A1;SLCO4C1;ABCB1;SLCO1B1;SLCO1C1 GO:0006979| response to oxidative stress ABL1;TPO GO:0030878| thyroid gland development THRA;MAP2K1 GO:0030154| cell differentiation SLCO4C1;SLC7A5;HCK;CAMK2G GO:0006810| transport ABCB1;SLC7A5 GO:0030218| erythrocyte differentiation LYN;THRA GO:0050900| leukocyte migration LYN;SRC;SLC7A5 GO:0055114| oxidation-reduction process CYP2C8;TPO;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;THRB;THRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;CDK2 GO:0007399| nervous system development CAMK2G;SLC7A5 GO:0007275| multicellular organismal development SLCO4C1;SLC7A5;CAMK2G;CDK2 6514:[DB06616 DB11118] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways GO:0009636| response to toxin LYN;CPS1 GO:0043200| response to amino acid stimulus CPS1;LYN GO:0008283| cell proliferation SRC;GLUL GO:0042493| response to drug LYN;CPS1;ABCB1;SRC GO:0032496| response to lipopolysaccharide CPS1;BCR GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;GLS2;MAP3K2 6515:[DB06616 DB07882] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07882|4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID IGKC common genes common pathways GO:0002376| immune system process HCK;SRC;LYN;IGKC GO:0038095| LYN;IGKC GO:0050853| B cell receptor signaling pathway IGKC;LYN;ABL1 GO:0045087| innate immune response ABL1;SRC;HCK;IGKC;LYN GO:0050900| leukocyte migration SRC;LYN;IGKC GO:0002250| adaptive immune response LYN;IGKC GO:0038096| LYN;IGKC;HCK;SRC;ABL1 6516:[DB06616 DB08766] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08766|Zofenoprilat LAP3 common genes common pathways 6517:[DB06616 DB01809] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes HCK common pathways GO:0000165| MAPKKK cascade CAMK2G;RET;MAP2K2;MAP2K1 GO:0019221| cytokine-mediated signaling pathway HCK GO:0038096| SRC;HCK;ABL1;LYN GO:0016032| viral reproduction LYN;HCK;SRC GO:0006954| inflammatory response LYN;HCK GO:2000251| positive regulation of actin cytoskeleton reorganization ABL1;HCK GO:0010976| positive regulation of neuron projection development LYN;RET GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;SRC;RET;MAP2K2;MAP2K1 GO:0006909| phagocytosis ABL1;HCK GO:0042493| response to drug LYN;ABCB1;SRC;RET GO:0038083| LYN;SRC;HCK;ABL1 GO:0007399| nervous system development CAMK2G;RET GO:0008360| regulation of cell shape HCK GO:0007155| cell adhesion ABL1;HCK;SRC;RET GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response HCK;SRC;ABL1;LYN GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;LYN GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0030155| regulation of cell adhesion ABL1;RET GO:0071300| cellular response to retinoic acid RET;LYN GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK GO:0050727| regulation of inflammatory response HCK;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K2;BCR;SRC;RET;MAP2K1;HCK;LYN GO:0007498| mesoderm development HCK GO:0045728| respiratory burst after phagocytosis HCK GO:0030838| positive regulation of actin filament polymerization HCK GO:0007411| axon guidance RET;SRC GO:0010628| positive regulation of gene expression SRC;RET;MAP2K1 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN GO:0002758| innate immune response-activating signal transduction HCK GO:0030182| neuron differentiation MAP2K1;RET;ABL1 GO:0050690| regulation of defense response to virus by virus HCK GO:0065009| regulation of molecular function CAMK2G;RET GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK GO:0007165| signal transduction MAP2K1;RET;SRC;BCR;LYN GO:0006887| exocytosis HCK GO:0002522| leukocyte migration involved in immune response HCK GO:0060333| interferon-gamma-mediated signaling pathway HCK;CAMK2G GO:0002376| immune system process HCK;SRC;LYN GO:0043299| leukocyte degranulation HCK GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0030154| cell differentiation HCK;CAMK2G GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;HCK;MAP2K1;SRC;RET;BCR;MAP2K2;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;RET;LYN GO:0030335| positive regulation of cell migration LYN;RET GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;RET;MAP2K2;BCR GO:0050764| regulation of phagocytosis HCK 6518:[DB06616 DB00833] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0055085| transmembrane transport SLC15A2;ABCB11;SLC22A8;SLC15A1;ABCB1 GO:0009636| response to toxin SLC22A8;LYN GO:0006810| transport ABCB1;SLC15A2;ABCB11;SLC15A1 GO:0006979| response to oxidative stress ABL1;MPO GO:0055114| oxidation-reduction process CYP3A4;MPO;CYP2C8 GO:0032496| response to lipopolysaccharide MPO;BCR GO:0043066| negative regulation of apoptotic process SRC;MPO;HCK GO:0009612| response to mechanical stimulus MPO;SRC 6519:[DB06616 DB01765] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01765|(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid CSNK2A1 common genes common pathways GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CSNK2A1 GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0007165| signal transduction CSNK2A1;LYN;SRC;BCR;MAP2K1 GO:0016310| phosphorylation MAP3K2;CSNK2A1;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;MAP3K2;CSNK2A1;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0007049| cell cycle CDK2;CSNK2A1;SRC GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CSNK2A1;CAMK2G GO:0006915| apoptotic process CSNK2A1;ABL1 6520:[DB06616 DB01549] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;DRD2 GO:0006816| calcium ion transport GRIN3A;CAMK2G GO:0048678| response to axon injury DRD2;LYN GO:0035556| intracellular signal transduction CAMK2G;LYN;DRD2;SRC;BCR GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;DRD2;MAP2K1;ABL1 GO:0009636| response to toxin LYN;DRD2 GO:0008285| negative regulation of cell proliferation DRD2;MAP2K1;LYN GO:0030336| negative regulation of cell migration DRD2;BCR GO:0030900| forebrain development DRD2;SRC GO:0007165| signal transduction LYN;MAP2K1;BCR;DRD2;SRC 6521:[DB06616 DB06788] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06788|Histrelin GNRHR common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;GNRHR GO:0007275| multicellular organismal development GNRHR;CAMK2G;CDK2 6522:[DB06616 DB03612] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0042493| response to drug HADH;LYN;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;HADH;CYP2C8 GO:0006629| lipid metabolic process HADH;CYP3A4 GO:0032868| response to insulin stimulus LYN;HADH GO:0009725| response to hormone stimulus LYN;HADH 6523:[DB06616 DB08399] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08399|PICEATANNOL ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 6524:[DB06616 DB02422] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02422|Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside MAN1B1 common genes common pathways 6525:[DB06616 DB07597] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07597|CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 6526:[DB06616 DB08287] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08287|(1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 6527:[DB06616 DB02457] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;LIPF GO:0006629| lipid metabolic process LIPF;CYP3A4 6528:[DB06616 DB04057] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways 6529:[DB06616 DB08831] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08831|2-deoxyglucose SLC2A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus SLC2A1;MAP3K2 GO:0042908| xenobiotic transport ABCB1;SLC2A1 GO:0032868| response to insulin stimulus LYN;SLC2A1 GO:0055085| transmembrane transport ABCB1;SLC2A1 6530:[DB06616 DB12323] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12323|Radotinib ABL1 common genes ABL1 common pathways GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0030100| regulation of endocytosis ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:1903053| ABL1 GO:0072358| cardiovascular system development ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0007229| integrin-mediated signaling pathway HCK;SRC;ABL1 GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR;CDK2;LYN;CAMK2G;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0001843| neural tube closure ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0048538| thymus development MAP2K1;ABL1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0048536| spleen development ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:1900026| ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:0006979| response to oxidative stress ABL1 GO:1902715| ABL1 GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:1905555| ABL1 GO:1903351| ABL1 GO:0090135| actin filament branching ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0030182| neuron differentiation ABL1;MAP2K1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;LYN GO:0045184| establishment of protein localization ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0042100| B cell proliferation ABL1 GO:0045580| regulation of T cell differentiation ABL1 GO:0002322| B cell proliferation involved in immune response ABL1 GO:0006915| apoptotic process ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;SRC;BCR GO:0001922| B-1 B cell homeostasis ABL1 GO:0050853| B cell receptor signaling pathway ABL1;LYN GO:0009791| post-embryonic development ABL1 GO:1990051| ABL1 GO:1900272| ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0006464| protein modification process ABL1 GO:0046632| alpha-beta T cell differentiation ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:1905244| ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0030516| regulation of axon extension ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0038189| ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0043542| endothelial cell migration ABL1 GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:1904528| ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030155| regulation of cell adhesion ABL1 GO:0030035| microspike assembly ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:0006897| endocytosis ABL1 GO:2000145| regulation of cell motility ABL1 GO:1900275| ABL1 GO:2000772| regulation of cellular senescence ABL1 GO:0007155| cell adhesion ABL1;SRC;HCK GO:0045087| innate immune response LYN;ABL1;SRC;HCK GO:0048668| collateral sprouting ABL1 GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2 GO:0051882| mitochondrial depolarization ABL1 GO:0006281| DNA repair ABL1;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:1900042| ABL1 GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0038083| LYN;ABL1;HCK;SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:1904531| ABL1 GO:1901216| ABL1 GO:0006909| phagocytosis HCK;ABL1 GO:0010506| regulation of autophagy ABL1 GO:0050885| neuromuscular process controlling balance ABL1;BCR GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN GO:0006914| autophagy ABL1 GO:0000278| mitotic cell cycle ABL1 GO:0006298| mismatch repair ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1 GO:0042770| signal transduction in response to DNA damage ABL1 GO:0030036| actin cytoskeleton organization ABL1;BCR GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN GO:1902036| ABL1 GO:0038096| ABL1;HCK;SRC;LYN GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 6531:[DB06616 DB01840] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ISYNA1 6532:[DB06616 DB02308] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02308|4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-Aminium PRSS3 common genes common pathways GO:0043542| endothelial cell migration PRSS3;ABL1 6533:[DB06616 DB02358] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02358|LY374571 MTHFD1 common genes common pathways GO:0001843| neural tube closure ABL1;MTHFD1 GO:0007507| heart development MTHFD1;MAP2K1 GO:0055114| oxidation-reduction process MTHFD1;CYP3A4;CYP2C8 6534:[DB06616 DB04864] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04864|Huperzine A ACHE common genes common pathways GO:0008283| cell proliferation ACHE;SRC GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0006260| DNA replication CDK2;ACHE 6535:[DB06616 DB06834] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways GO:0006954| inflammatory response HCK;LYN;SYK GO:0090330| regulation of platelet aggregation SYK;LYN GO:0016032| viral reproduction HCK;SRC;LYN;SYK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;SYK GO:0038096| SYK;LYN;ABL1;HCK;SRC GO:0002250| adaptive immune response LYN;SYK GO:0038083| SRC;HCK;ABL1;LYN;SYK GO:0018105| peptidyl-serine phosphorylation CAMK2G;SYK;CDK2;SRC GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;SYK;LYN GO:0045087| innate immune response LYN;SYK;HCK;SRC;ABL1 GO:0002223| stimulatory C-type lectin receptor signaling pathway SYK;LYN;SRC GO:0018108| peptidyl-tyrosine phosphorylation SYK;LYN;HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1 GO:0046777| protein autophosphorylation CAMK2G;LYN;SYK;ABL1;BCR;SRC;HCK GO:0050853| B cell receptor signaling pathway ABL1;LYN;SYK GO:0008283| cell proliferation SRC;SYK GO:0038095| LYN;SYK GO:0007257| activation of JUN kinase activity SYK;MAP3K2 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;SYK GO:0002376| immune system process SRC;HCK;SYK;LYN GO:0050715| positive regulation of cytokine secretion SYK;SRC GO:0070372| regulation of ERK1 and ERK2 cascade LYN;SYK GO:0051090| regulation of sequence-specific DNA binding transcription factor activity SYK;HCK GO:0016310| phosphorylation CAMK2G;SYK;LYN;CDK2;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0050764| regulation of phagocytosis SYK;HCK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;SYK GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC;SYK GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;LYN;CDK2;SYK;MAP3K2 GO:0030168| platelet activation LYN;SYK;SRC 6536:[DB06616 DB07715] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07715|Emodin CSNK2A1;fabZ;AHR common genes common pathways GO:0007165| signal transduction CSNK2A1;LYN;SRC;BCR;MAP2K1 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;CSNK2A1;MAP3K2 GO:0016310| phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;MAP3K2;CSNK2A1 GO:0007049| cell cycle AHR;CSNK2A1;CDK2;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;AHR GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CSNK2A1;CAMK2G GO:0006915| apoptotic process ABL1;AHR;CSNK2A1 GO:0009636| response to toxin LYN;AHR GO:1901796| CDK2;CSNK2A1 GO:0008284| positive regulation of cell proliferation HCK;CSNK2A1;LYN;CDK2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;AHR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent AHR;CSNK2A1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;AHR;MAP3K2;MAP2K1;MAP2K2;SRC 6537:[DB06616 DB08691] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08691|ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate CLK1;CLK3 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation LYN;CLK1;CLK3;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G;CLK1 GO:0016310| phosphorylation CLK1;MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;CLK3;ABL1 GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;CLK3;ABL1;MAP3K2;CLK1;LYN;CDK2;CAMK2G GO:0008283| cell proliferation SRC;CLK1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CLK1 GO:0046777| protein autophosphorylation CLK1;LYN;CAMK2G;HCK;BCR;SRC;CLK3;ABL1 6538:[DB06616 DB00161] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:0008283| cell proliferation BCAT1;SRC GO:0000082| G1/S transition of mitotic cell cycle BCAT1;CDK2;CAMK2G 6539:[DB06616 DB05152] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05152|NGX267 CHRM1 common genes common pathways GO:0008283| cell proliferation CHRM1;SRC GO:0006464| protein modification process ABL1;CHRM1 GO:0007165| signal transduction LYN;CHRM1;MAP2K1;BCR;SRC GO:0007399| nervous system development CAMK2G;CHRM1 GO:0008284| positive regulation of cell proliferation CHRM1;LYN;CDK2;HCK 6540:[DB06616 DB01940] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01940|Balanol Analog 2 PRKACA common genes common pathways GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;PRKACA;LYN;CDK2;CAMK2G GO:0034605| cellular response to heat PRKACA;LYN GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;PRKACA;LYN;CDK2;CAMK2G GO:0000086| G2/M transition of mitotic cell cycle PRKACA;CDK2;ABCB1 GO:0007596| blood coagulation PRKACA;LYN GO:0018105| peptidyl-serine phosphorylation CDK2;PRKACA;CAMK2G;SRC GO:0043393| regulation of protein binding SRC;PRKACA GO:0002223| stimulatory C-type lectin receptor signaling pathway PRKACA;LYN;SRC GO:0010389| regulation of G2/M transition of mitotic cell cycle PRKACA;CDK2 6541:[DB06616 DB01931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways GO:0048013| ephrin receptor signaling pathway LYN;GRIN1;SRC GO:0065009| regulation of molecular function GRIN1;CAMK2G GO:0000165| MAPKKK cascade CAMK2G;GRIN1;MAP2K2;MAP2K1 GO:0006816| calcium ion transport GRIN1;CAMK2G GO:0043065| positive regulation of apoptotic process GRIN1;SRC;ABL1 6542:[DB06616 DB04954] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04954|Tecadenoson ADORA1 common genes common pathways GO:0008285| negative regulation of cell proliferation ADORA1;LYN;MAP2K1 GO:0007165| signal transduction LYN;ADORA1;MAP2K1;BCR;SRC GO:0000186| activation of MAPKK activity MAP3K2;ADORA1 GO:0006954| inflammatory response ADORA1;LYN;HCK GO:0050728| negative regulation of inflammatory response BCR;ADORA1 GO:0006909| phagocytosis ADORA1;ABL1;HCK GO:0007399| nervous system development ADORA1;CAMK2G GO:0043066| negative regulation of apoptotic process ADORA1;SRC;HCK 6543:[DB06616 DB01189] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes common pathways GO:0006810| transport GABRB3;ABCB1;GABRA1;GABRA4;GABRA6;GABRD;GABRB2;GABRA5;GABRG2;GABRB1;GABRA3 GO:0007417| central nervous system development SRC;LYN;GABRA4 GO:0007165| signal transduction GABRP;LYN;GABRA6;GABRD;GABRB1;GABRA5;GABRQ;GABRE;GABRB3;ATP2C1;GRIA1;MAP2K1;BCR;SRC GO:0007420| brain development KCNA1;BCR;GABRA5 GO:0006813| potassium ion transport KCNA1;CDK2 GO:0055085| transmembrane transport KCNA1;ABCB1 GO:0009636| response to toxin GABRB1;LYN GO:0014070| response to organic cyclic compound LYN;MT-ND1 GO:0009791| post-embryonic development ABL1;GABRG2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ATP2C1 GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0055114| oxidation-reduction process CYP3A4;MT-ND1;CYP2C8 GO:0042493| response to drug ABCB1;SRC;GABRG3;MT-ND1;LYN GO:0006816| calcium ion transport CAMK2G;ATP2C1 6544:[DB06616 DB05110] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05110|VIR201 IFNG common genes common pathways GO:0009615| response to virus IFNG;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;IFNG GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;CDK2 GO:0010634| positive regulation of epithelial cell migration IFNG;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IFNG GO:0002250| adaptive immune response LYN;IFNG GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;IFNG GO:0001934| positive regulation of protein phosphorylation LYN;IFNG;ABL1 GO:0060333| interferon-gamma-mediated signaling pathway HCK;IFNG;CAMK2G GO:0007050| cell cycle arrest MAP2K1;IFNG;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;IFNG GO:0006928| cellular component movement MAP2K1;IFNG GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;IFNG GO:0045892| negative regulation of transcription, DNA-dependent SRC;IFNG GO:0006915| apoptotic process IFNG;ABL1 6545:[DB06616 DB04307] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04307|5-Hydroxy-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0009636| response to toxin MAOB;LYN GO:0042493| response to drug MAOB;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process MAOB;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide BCR;MAOB 6546:[DB06616 DB04899] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;NPR1;SRC;MAP2K2;NPR2;BCR;LYN;CDK2;CAMK2G;MAP3K2 GO:0035556| intracellular signal transduction LYN;CAMK2G;NPR1;BCR;NPR2;SRC GO:0043114| regulation of vascular permeability BCR;SRC;NPR1 6547:[DB06616 DB05829] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05829|Parathyroid hormone PTH1R;PTH2R common genes common pathways GO:0008284| positive regulation of cell proliferation PTH1R;CDK2;LYN;HCK GO:0007204| elevation of cytosolic calcium ion concentration ABL1;PTH1R GO:0007165| signal transduction LYN;PTH1R;PTH2R;MAP2K1;BCR;SRC GO:0045453| bone resorption PTH1R;SRC GO:0008285| negative regulation of cell proliferation LYN;PTH1R;MAP2K1 6548:[DB06616 DB06194] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06194|Elocalcitol VDR common genes common pathways GO:0007165| signal transduction MAP2K1;VDR;SRC;BCR;LYN GO:0008285| negative regulation of cell proliferation LYN;VDR;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;VDR GO:0010628| positive regulation of gene expression VDR;MAP2K1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;CDK2 GO:0007275| multicellular organismal development CDK2;CAMK2G;VDR GO:0006816| calcium ion transport CAMK2G;VDR GO:0006355| regulation of transcription, DNA-dependent ABL1;VDR 6549:[DB06616 DB12116] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0006915| apoptotic process ABL1;AHR GO:0009636| response to toxin LYN;AHR GO:0007049| cell cycle AHR;CDK2;SRC GO:0045892| negative regulation of transcription, DNA-dependent AHR;SRC;DNMT1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;DNMT1 GO:0007265| Ras protein signal transduction CDK2;DNMT1 GO:0042127| regulation of cell proliferation SRC;DNMT1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DNMT1 GO:0006805| xenobiotic metabolic process CYP3A4;AHR;CYP2C8 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;AHR;MAP3K2;MAP2K1;MAP2K2;SRC GO:0006355| regulation of transcription, DNA-dependent DNMT1;ABL1;AHR 6550:[DB06616 DB02104] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHFR 6551:[DB06616 DB05846] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05846|Mito-4509 APP common genes common pathways GO:0006897| endocytosis ABL1;APP GO:0042327| positive regulation of phosphorylation LYN;APP GO:0002576| platelet degranulation APP;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;APP GO:0045087| innate immune response ABL1;SRC;HCK;LYN;APP GO:0007155| cell adhesion ABL1;SRC;HCK;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0007399| nervous system development APP;CAMK2G GO:0045931| positive regulation of mitotic cell cycle ABL1;APP GO:0043393| regulation of protein binding APP;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;APP;ABL1;SRC GO:1901216| ABL1;APP GO:0010629| negative regulation of gene expression APP;MAP2K1;MAP2K2 GO:0001934| positive regulation of protein phosphorylation ABL1;APP;LYN GO:0050885| neuromuscular process controlling balance BCR;ABL1;APP GO:0006979| response to oxidative stress ABL1;APP GO:0030900| forebrain development APP;SRC GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;APP;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP GO:0010628| positive regulation of gene expression MAP2K1;SRC;APP GO:1900272| APP;ABL1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;APP GO:0031175| neuron projection development LYN;APP GO:0000187| activation of MAPK activity MAP3K2;APP;MAP2K2;MAP2K1 GO:0006915| apoptotic process ABL1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;APP 6552:[DB06616 DB08802] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08802|Isothipendyl HRH1 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;HRH1 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0006954| inflammatory response LYN;HRH1;HCK 6553:[DB06616 DB02035] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;HCK;PPT1 GO:0007399| nervous system development CAMK2G;PPT1 GO:0007420| brain development PPT1;BCR 6554:[DB06616 DB01051] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01051|Novobiocin gyrB;topA;SLC22A6;SLC22A8;SLC22A11;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0042493| response to drug LYN;ABCG2;ABCB1;SRC GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0009636| response to toxin LYN;SLC22A8 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0055085| transmembrane transport SLC22A8;SLCO1B1;SLCO1B3;SLC22A6;SLC22A11;SLCO2B1;ABCG2;ABCB1 6555:[DB06616 DB13919] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13919|Candesartan AGTR1;CYP2C8;CYP2C9;UGT1A3;PTGS1;ABCB1;SLCO1B1 common genes CYP2C8;ABCB1 common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LYN GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP2C9;CYP3A4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006954| inflammatory response PTGS1;HCK;LYN GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation ABL1;AGTR1;SRC;PTGS1 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8;PTGS1 GO:0050727| regulation of inflammatory response LYN;AGTR1;HCK GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS1 GO:0006082| organic acid metabolic process CYP2C8 GO:0002933| CYP2C8;CYP3A4 GO:0055085| transmembrane transport SLCO1B1;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ABL1 GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A3;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0007165| signal transduction LYN;AGTR1;MAP2K1;BCR;SRC 6556:[DB06616 DB04891] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04891|Becocalcidiol MED1;VDR common genes common pathways GO:0007165| signal transduction MAP2K1;VDR;BCR;SRC;LYN GO:0007420| brain development MED1;BCR GO:0010628| positive regulation of gene expression MAP2K1;MED1;VDR;SRC GO:0008285| negative regulation of cell proliferation LYN;VDR;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC GO:0030216| keratinocyte differentiation MAP2K1;MED1 GO:0043066| negative regulation of apoptotic process SRC;HCK;MED1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;MED1 GO:0051726| regulation of cell cycle MED1;BCR;SRC;ABL1 GO:0007507| heart development MED1;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;MED1;CDK2 GO:0007275| multicellular organismal development CAMK2G;CDK2;VDR;MED1 GO:0006816| calcium ion transport VDR;CAMK2G GO:0070371| ERK1 and ERK2 cascade MED1;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MED1;MAP2K1;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent MED1;VDR;ABL1 6557:[DB06616 DB00610] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00610|Metaraminol ADRA1A common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;ADRA1A;SRC GO:0006915| apoptotic process ADRA1A;ABL1 GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ADRA1A GO:0007165| signal transduction LYN;BCR;ADRA1A;SRC;MAP2K1 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0042493| response to drug ABCB1;ADRA1A;SRC;LYN GO:0035556| intracellular signal transduction LYN;CAMK2G;BCR;ADRA1A;SRC 6558:[DB06616 DB02597] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways 6559:[DB06616 DB02309] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 6560:[DB06616 DB13978] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13978|Selisistat SIRT1 common genes common pathways GO:0032868| response to insulin stimulus SIRT1;LYN GO:0006915| apoptotic process ABL1;SIRT1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;SIRT1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis SIRT1;ABL1 GO:0070301| cellular response to hydrogen peroxide SIRT1;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent SIRT1;SRC GO:0030154| cell differentiation CAMK2G;SIRT1;HCK GO:0071456| cellular response to hypoxia SIRT1;SRC GO:0031648| protein destabilization SIRT1;SRC GO:0006979| response to oxidative stress SIRT1;ABL1 GO:1900034| CAMK2G;SIRT1 GO:2000773| negative regulation of cellular senescence SIRT1;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;SIRT1;LYN GO:0010629| negative regulation of gene expression MAP2K1;SIRT1;MAP2K2 GO:0007346| regulation of mitotic cell cycle MAP3K2;MAP2K1;MAP2K2;SIRT1 GO:0006355| regulation of transcription, DNA-dependent ABL1;SIRT1 GO:0046628| positive regulation of insulin receptor signaling pathway SRC;SIRT1 GO:0006260| DNA replication SIRT1;CDK2 GO:0016032| viral reproduction HCK;SIRT1;SRC;LYN GO:0007275| multicellular organismal development SIRT1;CAMK2G;CDK2 GO:0042127| regulation of cell proliferation ABL1;SIRT1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade SIRT1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;SIRT1 GO:0042981| regulation of apoptotic process SIRT1;MAP2K2;MAP2K1;MAP3K2 GO:0006281| DNA repair ABL1;SIRT1;CDK2 GO:0006974| response to DNA damage stimulus CDK2;LYN;ABL1;SIRT1 GO:0043065| positive regulation of apoptotic process SRC;SIRT1;ABL1 GO:0042542| response to hydrogen peroxide SRC;SIRT1 GO:0008284| positive regulation of cell proliferation SIRT1;HCK;LYN;CDK2 GO:0043066| negative regulation of apoptotic process HCK;SIRT1;SRC 6561:[DB06616 DB02547] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 6562:[DB06616 DB03573] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03573|WRR-99 CTSF common genes common pathways 6563:[DB06616 DB06429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06429|Talnetant TACR3 common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;TACR3;BCR;SRC 6564:[DB06616 DB00644] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways GO:0007165| signal transduction LYN;GNRHR;BCR;SRC;MAP2K1;GNRHR2 GO:0007275| multicellular organismal development GNRHR;CDK2;CAMK2G 6565:[DB06616 DB04927] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04927|NM100060 SQLE common genes common pathways GO:0010033| response to organic substance SQLE;CDK2 GO:0055114| oxidation-reduction process CYP2C8;SQLE;CYP3A4 6566:[DB06616 DB02834] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02834|IDD552 AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 GO:0010033| response to organic substance CDK2;AKR1B1 6567:[DB06616 DB14543] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes CYP3A4;ABCB1;CYP2C8 common pathways GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042127| regulation of cell proliferation ABL1;ANXA1;SRC GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0043065| positive regulation of apoptotic process ABL1;ANXA1;SRC GO:0050727| regulation of inflammatory response LYN;ANXA1;HCK GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;ANXA1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0006082| organic acid metabolic process CYP2C8 GO:0008360| regulation of cell shape ANXA1;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0045087| innate immune response ANXA1;ABL1;SRC;HCK;LYN GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4 GO:0030073| insulin secretion CAMK2G;ANXA1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0042493| response to drug ABCB1;SRC;ANXA1;ABCG2;HSD11B2;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006909| phagocytosis ANXA1;ABL1;HCK GO:0008209| androgen metabolic process CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;ABL1 GO:0055114| oxidation-reduction process CYP3A7;CYP11B2;CYP11B1;CYP3A4;HSD3B1;HSD11B2;CYP3A5;CYP2C8 GO:0006954| inflammatory response HCK;ANXA1;LYN GO:0051301| cell division CDK2;NR3C1 GO:0002250| adaptive immune response ANXA1;LYN GO:0072089| stem cell proliferation ABCB1 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP3A4;CYP3A7;CYP11B2;CYP11B1 GO:0043434| response to peptide hormone stimulus LYN;ANXA1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0098609| ANXA1;SRC GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0002376| immune system process SRC;HCK;ANXA1;LYN GO:0009725| response to hormone stimulus LYN;ANXA1 GO:0007165| signal transduction MAP2K1;BCR;SRC;ANXA1;NR3C1;LYN GO:0097267| CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070555| response to interleukin-1 ANXA1;SRC GO:0030216| keratinocyte differentiation ANXA1;MAP2K1 GO:0014070| response to organic cyclic compound LYN;ANXA1 GO:0009636| response to toxin LYN;SLC22A8 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0036378| CYP3A4 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0032868| response to insulin stimulus LYN;HSD11B2 GO:0006915| apoptotic process NR3C1;ABL1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0070301| cellular response to hydrogen peroxide ABL1;ANXA1 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0046632| alpha-beta T cell differentiation ABL1;ANXA1 6568:[DB06616 DB07641] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA 6569:[DB06616 DB04235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0042493| response to drug ABCB1;SRC;ABAT;LYN 6570:[DB06616 DB05541] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C9;CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0007399| nervous system development SCN3B;SCN2B;SCN2A;CAMK2G;SCN8A GO:0007155| cell adhesion ABL1;HCK;SRC;SCN1B GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP2B6;CYP2C9;CYP3A4 GO:0042493| response to drug ABCB1;SRC;SCN11A;LYN GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP2C9 GO:0006954| inflammatory response SCN9A;LYN;HCK GO:0010976| positive regulation of neuron projection development SCN1B;LYN GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0009636| response to toxin LYN;SCN9A GO:0002933| CYP3A4;CYP2C8 GO:0055085| transmembrane transport SCN10A;SCN8A;SCN11A;SCN9A;SV2A;SCN7A;SCN2A;SCN5A;SCN3A;SCN1A;ABCB1;SCN4A GO:0036378| CYP3A4 GO:0009791| post-embryonic development ABL1;SCN9A GO:0042359| vitamin D metabolic process CYP3A4 GO:0007411| axon guidance SRC;SCN1B GO:0009822| alkaloid catabolic process CYP3A4 6571:[DB06616 DB00389] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways GO:0006979| response to oxidative stress TPO;ABL1 GO:0060065| uterus development SRC;CYP19A1 GO:0055114| oxidation-reduction process CYP2C8;TPO;CYP3A4;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 6572:[DB06616 DB01164] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01164|Calcium Chloride S100A13 common genes common pathways GO:0050663| cytokine secretion S100A13;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100A13;ABL1 GO:0008360| regulation of cell shape HCK;S100A13 GO:0008284| positive regulation of cell proliferation HCK;S100A13;LYN;CDK2 GO:0051602| response to electrical stimulus SRC;S100A13 6573:[DB06616 DB06678] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;HTR2C;HTR2B;ABL1;HTR2A GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;ADRA2B;MAP3K2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC;ADRA2A;HTR2B GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0030168| platelet activation LYN;ADRA2B;ADRA2C;SRC;ADRA2A GO:0016310| phosphorylation HTR2B;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0043547| positive regulation of GTPase activity BCR;HTR2B GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction HRH1;ADRA2C;HTR2A;ADRA2B;LYN;BCR;SRC;MAP2K1;HTR2B;HTR2C;ADRA2A GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0050715| positive regulation of cytokine secretion HTR2B;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0043114| regulation of vascular permeability SRC;BCR;HRH1 GO:0042493| response to drug LYN;HTR2A;HTR2C;HTR2B;SRC;ABCB1 GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;ABL1;SRC GO:0006954| inflammatory response HCK;HRH1;LYN GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K2;MAP2K1 GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;HTR2B GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0007507| heart development HTR2B;MAP2K1 GO:0032148| activation of protein kinase B activity ADRA2B;ADRA2C;SRC;ADRA2A GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HTR2A;LYN;CDK2;HCK;HTR2B;ADRA2A GO:0043066| negative regulation of apoptotic process HCK;SRC;HTR2B GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 6574:[DB06616 DB08703] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways GO:0000186| activation of MAPKK activity MAP3K9;MAP3K2 GO:0006468| protein phosphorylation CDK2;LYN;MAP3K9;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0016310| phosphorylation MAP3K2;LYN;CDK2;MAP3K9;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0006915| apoptotic process ABL1;MAP3K9 GO:0007257| activation of JUN kinase activity MAP3K9;MAP3K2 GO:0046777| protein autophosphorylation LYN;CAMK2G;MAP3K9;HCK;BCR;SRC;ABL1 GO:0043065| positive regulation of apoptotic process MAP3K9;ABL1;SRC GO:0006355| regulation of transcription, DNA-dependent MAP3K9;ABL1 6575:[DB06616 DB00740] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0007420| brain development SLC7A11;BCR GO:0017144| drug metabolic process CYP3A4;CYP1A1;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2;CYP1A1 GO:0006979| response to oxidative stress ABL1;SLC7A11 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP1A1;CYP3A4;CYP1A2 GO:0010033| response to organic substance CDK2;CYP1A1;CYP1A2 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0055085| transmembrane transport SCN5A;ABCG2;ABCB1 GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0009636| response to toxin LYN;CYP1A1;SLC7A11 GO:0014070| response to organic cyclic compound CYP1A1;LYN;CYP1A2 GO:0008283| cell proliferation CYP1A1;SRC GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP1A1 GO:0009615| response to virus CYP1A1;SRC GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP1A1;CYP3A4 GO:0050900| leukocyte migration SLC7A11;LYN;SRC GO:0042493| response to drug ABCB1;SRC;ABCG2;CYP1A2;LYN;CYP1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 6576:[DB06616 DB06941] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06941|(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide S100B common genes common pathways GO:0008283| cell proliferation SRC;S100B GO:0007417| central nervous system development LYN;SRC;S100B GO:0071456| cellular response to hypoxia SRC;S100B GO:0043065| positive regulation of apoptotic process S100B;SRC;ABL1 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;S100B GO:0008360| regulation of cell shape HCK;S100B GO:0045087| innate immune response S100B;HCK;SRC;ABL1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;S100B 6577:[DB06616 DB07268] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07268|2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE MAPK8 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAPK8;MAP3K2 GO:0043066| negative regulation of apoptotic process HCK;MAPK8;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;MAPK8 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;MAPK8;ABL1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;MAPK8;SRC GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;MAPK8;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0016310| phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;MAPK8;HCK;CAMK2G;LYN;CDK2;MAP3K2 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity MAPK8;HCK GO:0018107| peptidyl-threonine phosphorylation MAPK8;MAP2K1;CAMK2G GO:0038095| LYN;MAPK8 GO:0010628| positive regulation of gene expression SRC;MAPK8;MAP2K1 GO:0034614| cellular response to reactive oxygen species MAPK8;SRC 6578:[DB06616 DB01482] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug LYN;CYP1A2;ABCB1;SRC GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 6579:[DB06616 DB01297] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01297|Practolol ADRB1;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;ADRB1;SRC;BCR;LYN GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity BCR;ADRB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 6580:[DB06616 DB11772] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11772|Pilaralisib PIK3CA common genes common pathways GO:0048010| vascular endothelial growth factor receptor signaling pathway PIK3CA;SRC GO:0045087| innate immune response ABL1;PIK3CA;SRC;HCK;LYN GO:0043542| endothelial cell migration ABL1;PIK3CA GO:0006954| inflammatory response LYN;HCK;PIK3CA GO:2000811| negative regulation of anoikis PIK3CA;SRC GO:0038128| SRC;PIK3CA GO:0038096| SRC;PIK3CA;HCK;ABL1;LYN GO:0051897| positive regulation of protein kinase B signaling cascade SRC;PIK3CA GO:0002250| adaptive immune response PIK3CA;LYN GO:0007173| epidermal growth factor receptor signaling pathway SRC;PIK3CA;ABL1 GO:0006909| phagocytosis HCK;PIK3CA;ABL1 GO:0050900| leukocyte migration SRC;PIK3CA;LYN GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;PIK3CA;MAP2K1;HCK;CAMK2G;LYN;CDK2;MAP3K2 GO:0031295| T cell costimulation LYN;PIK3CA;SRC GO:0006468| protein phosphorylation PIK3CA;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0030168| platelet activation LYN;PIK3CA;SRC GO:0007411| axon guidance SRC;PIK3CA GO:0038095| PIK3CA;LYN 6581:[DB06616 DB02095] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02095|Isatin MAOB;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0042493| response to drug SRC;ABCB1;MAOB;LYN GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 GO:0009636| response to toxin MAOB;LYN 6582:[DB06616 DB09568] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 GO:0097267| CYP2C8;CYP4F2 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP4F2 GO:0009725| response to hormone stimulus LYN;HADH GO:0007596| blood coagulation CYP4F2;LYN GO:0002933| CYP3A5;CYP2C8;CYP3A7;CYP3A4 GO:0032868| response to insulin stimulus HADH;LYN GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP4F2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0006629| lipid metabolic process ELOVL4;ECHS1;LPL;HADH;CYP3A4;HSD17B10;DGAT2 GO:0006706| steroid catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug LYN;HADH;LPL;ABCB1;SRC GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process HADH;CYP3A4;HSD17B10;CYP3A7;CYP3A5;CYP2C8;CYP4F2;CYP3A43 GO:0000165| MAPKKK cascade MAP2K1;PEBP1;MAP2K2;CAMK2G 6583:[DB06616 DB11994] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes CYP3A4 common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;NR1H3;MAP2K1;MAP3K2;NR1H2;CDK2 GO:0006355| regulation of transcription, DNA-dependent NR1H2;ABL1;NR1H3 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NR1H2 GO:0042493| response to drug LYN;CYP2E1;CYP1A2;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C8;ALOX5;CYP3A43 GO:0008209| androgen metabolic process CYP3A4 GO:0006954| inflammatory response HCK;ALOX5;LYN GO:0050728| negative regulation of inflammatory response NR1H3;BCR GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP2C9;CYP2E1;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP3A4;CYP2C9;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;CYP2C9;CYP2E1;CYP2D6;CYP2C8;CYP3A5 GO:0071222| cellular response to lipopolysaccharide ABL1;NR1H3;SRC;BCR GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR1H2;NR1H3 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression NR1H2;SRC;MAP2K1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0045892| negative regulation of transcription, DNA-dependent NR1H2;SRC GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP3A7;CYP1A2;CYP2D6;CYP2C8;CYP3A5 GO:0070989| oxidative demethylation CYP1A2;CYP2C9;CYP3A4;CYP3A5;CYP2C8;CYP2D6 GO:0097267| CYP2C8;CYP1A2;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP2C9;CYP3A4 6584:[DB06616 DB00491] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways GO:0050885| neuromuscular process controlling balance ABL1;BCR;GAA 6585:[DB06616 DB04556] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways GO:0006260| DNA replication CDK2;ACHE GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0008283| cell proliferation ACHE;SRC 6586:[DB06616 DB09008] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A8 6587:[DB06616 DB06436] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06436|Semaxanib KDR;PTGS2 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;KDR GO:0006954| inflammatory response HCK;PTGS2;LYN GO:0016032| viral reproduction SRC;KDR;HCK;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8 GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;KDR GO:0038083| ABL1;KDR;HCK;SRC;LYN GO:0042493| response to drug LYN;PTGS2;SRC;ABCB1 GO:0008360| regulation of cell shape HCK;KDR GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1;SRC GO:0008284| positive regulation of cell proliferation KDR;HCK;LYN;CDK2;PTGS2 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR GO:0043066| negative regulation of apoptotic process SRC;HCK;KDR;PTGS2 GO:0007275| multicellular organismal development KDR;CDK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;KDR;ABL1;LYN GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;KDR;ABL1;CAMK2G;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2;SRC;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR;ABL1 GO:0030154| cell differentiation KDR;HCK;CAMK2G GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0010595| positive regulation of endothelial cell migration ABL1;KDR GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;KDR;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0030335| positive regulation of cell migration KDR;LYN GO:0034605| cellular response to heat PTGS2;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;KDR;HCK 6588:[DB06616 DB04970] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04970|Lesopitron HTR1A common genes common pathways GO:0007165| signal transduction LYN;HTR1A;MAP2K1;SRC;BCR GO:0008283| cell proliferation SRC;HTR1A GO:0008284| positive regulation of cell proliferation HCK;HTR1A;CDK2;LYN 6589:[DB06616 DB00335] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes ABCB1 common pathways GO:0007165| signal transduction ADRB2;LYN;MAP2K1;BCR;SRC;ADRB1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0045453| bone resorption SRC;ADRB2 GO:0006810| transport ABCB11;ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0072089| stem cell proliferation ABCB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;ADRB2 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCB1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042493| response to drug LYN;SRC;ABCB1 6590:[DB06616 DB06867] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways GO:0043547| positive regulation of GTPase activity BCR;PIN1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway PIN1;SRC GO:0007049| cell cycle SRC;PIN1;CDK2 GO:0030182| neuron differentiation ABL1;PIN1;MAP2K1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1;PIN1 GO:1901796| PIN1;CDK2 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;PIN1 6591:[DB06616 DB07412] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;LYN;DPP4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0007155| cell adhesion HCK;SRC;ABL1;DPP4 GO:0043542| endothelial cell migration ABL1;DPP4 6592:[DB06616 DB02710] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02710|2,3,-Dihydroxybenzoylserine LCN2 common genes common pathways GO:0045087| innate immune response ABL1;HCK;LCN2;SRC;LYN GO:0002376| immune system process LCN2;SRC;HCK;LYN GO:0006915| apoptotic process ABL1;LCN2 6593:[DB06616 DB01681] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways 6594:[DB06616 DB08492] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;ALOX15;MAP2K1;MAP2K2;SRC GO:0055114| oxidation-reduction process CYP2C8;ALOX15;CYP3A4 GO:0006954| inflammatory response LYN;HCK;ALOX15 GO:0030838| positive regulation of actin filament polymerization ALOX15;HCK GO:0006629| lipid metabolic process CYP3A4;ALOX15 6595:[DB06616 DB02504] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02504|[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid PLA2G2A common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;PLA2G2A GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 6596:[DB06616 DB07076] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07076|6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE PLAU common genes common pathways GO:0006935| chemotaxis PLAU;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;PLAU GO:0007165| signal transduction SRC;BCR;MAP2K1;PLAU;LYN GO:0030335| positive regulation of cell migration PLAU;LYN GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007596| blood coagulation PLAU;LYN 6597:[DB06616 DB08651] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways GO:0030900| forebrain development SRC;TOP2B 6598:[DB06616 DB07271] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways GO:0043542| endothelial cell migration ABL1;DPP4 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0031295| T cell costimulation LYN;DPP4;SRC 6599:[DB06616 DB09013] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2;ADRB2 GO:0007165| signal transduction BCR;ADRB1;SRC;MAP2K1;LYN;ADRB2 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0045453| bone resorption ADRB2;SRC GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 6600:[DB06616 DB06856] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06856|6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE PLAU common genes common pathways GO:0006935| chemotaxis MAP2K1;PLAU GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC GO:0007165| signal transduction PLAU;SRC;BCR;MAP2K1;LYN GO:0030335| positive regulation of cell migration LYN;PLAU GO:0033628| regulation of cell adhesion mediated by integrin LYN;PLAU GO:0007596| blood coagulation PLAU;LYN 6601:[DB06616 DB04612] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04612|N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE XIAP common genes common pathways GO:0006915| apoptotic process XIAP;ABL1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;XIAP GO:0042127| regulation of cell proliferation ABL1;SRC;XIAP GO:0043066| negative regulation of apoptotic process XIAP;SRC;HCK GO:0050727| regulation of inflammatory response HCK;XIAP;LYN GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;XIAP GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process XIAP;SRC 6602:[DB06616 DB03181] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent SRC;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;THRB GO:0006355| regulation of transcription, DNA-dependent THRB;ABL1 6603:[DB06616 DB09302] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09302|Alirocumab PCSK9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PCSK9 GO:0006915| apoptotic process ABL1;PCSK9 GO:0030182| neuron differentiation PCSK9;MAP2K1;ABL1 GO:0032869| cellular response to insulin stimulus PCSK9;SRC GO:0008202| steroid metabolic process CYP2C8;PCSK9;CYP3A4 6604:[DB06616 DB03906] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0006979| response to oxidative stress ABL1;HMOX1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;HMOX1 GO:0034605| cellular response to heat HMOX1;LYN GO:0071456| cellular response to hypoxia HMOX1;SRC GO:0008285| negative regulation of cell proliferation LYN;HMOX1;MAP2K1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;HMOX1 GO:0006915| apoptotic process ABL1;HMOX1 GO:0035556| intracellular signal transduction LYN;HMOX1;CAMK2G;SRC;BCR GO:0042542| response to hydrogen peroxide SRC;HMOX1 GO:0043065| positive regulation of apoptotic process HMOX1;SRC;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;ABL1 GO:0055114| oxidation-reduction process CYP2C8;HMOX1;CYP3A4 6605:[DB06616 DB13044] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13044|Gossypol BCL2L1 common genes common pathways GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;BCL2L1;MAP3K2 GO:0008284| positive regulation of cell proliferation HCK;BCL2L1;CDK2;LYN GO:0009615| response to virus SRC;BCL2L1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;BCL2L1 GO:0043066| negative regulation of apoptotic process SRC;HCK;BCL2L1 GO:0006897| endocytosis ABL1;BCL2L1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2L1 GO:2000811| negative regulation of anoikis SRC;BCL2L1 GO:0006915| apoptotic process ABL1;BCL2L1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;BCL2L1 GO:0008283| cell proliferation SRC;BCL2L1 6606:[DB06616 DB12789] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12789|Dinoprost PTGDR2 common genes common pathways GO:0006935| chemotaxis MAP2K1;PTGDR2 GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;PTGDR2 6607:[DB06616 DB08321] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08321|(1S,2S,3R,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol MAN2A1 common genes common pathways 6608:[DB06616 DB01852] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01852|Kaempherol UGT3A1 common genes common pathways 6609:[DB06616 DB02235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02235|L-methionine (R)-S-oxide APP common genes common pathways GO:0001934| positive regulation of protein phosphorylation ABL1;APP;LYN GO:0050885| neuromuscular process controlling balance APP;ABL1;BCR GO:1901216| ABL1;APP GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;APP GO:0051897| positive regulation of protein kinase B signaling cascade SRC;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;APP;ABL1;SRC GO:0043393| regulation of protein binding SRC;APP GO:0045931| positive regulation of mitotic cell cycle ABL1;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;APP GO:0045087| innate immune response HCK;SRC;ABL1;APP;LYN GO:0007155| cell adhesion SRC;HCK;ABL1;APP GO:0007399| nervous system development CAMK2G;APP GO:0006897| endocytosis APP;ABL1 GO:0042327| positive regulation of phosphorylation APP;LYN GO:0002576| platelet degranulation LYN;APP GO:0043065| positive regulation of apoptotic process SRC;ABL1;APP GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;APP GO:0006915| apoptotic process ABL1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;MAP2K1;SRC;MAP2K2;ABL1 GO:0031175| neuron projection development LYN;APP GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;APP GO:0010628| positive regulation of gene expression SRC;MAP2K1;APP GO:1900272| ABL1;APP GO:0006468| protein phosphorylation APP;MAP3K2;CDK2;LYN;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP GO:0030900| forebrain development APP;SRC GO:0006979| response to oxidative stress APP;ABL1 6610:[DB06616 DB05147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05147|CYT997 TUBA1A;TUBA1B;TUBA1C;TUBA4A;TUBA3C;TUBA3E;TUBA4B;TUBB1;TUBB2A;TUBB2B;TUBB4B;TUBB3;TUBB4A;TUBB;TUBB6 common genes common pathways GO:0007411| axon guidance SRC;TUBB3 GO:0006928| cellular component movement MAP2K1;TUBB;TUBB4B GO:0000086| G2/M transition of mitotic cell cycle TUBB4B;CDK2;TUBB4A;TUBA1A;TUBB;TUBA4A;ABCB1 GO:0030182| neuron differentiation TUBB3;ABL1;MAP2K1 GO:0010389| regulation of G2/M transition of mitotic cell cycle TUBB4B;CDK2;TUBB4A;TUBA1A;TUBB;TUBA4A GO:0051301| cell division TUBA1B;TUBA1C;CDK2;TUBB;TUBA1A GO:0000278| mitotic cell cycle ABL1;TUBB3 GO:0007399| nervous system development CAMK2G;TUBB2B GO:0002576| platelet degranulation LYN;TUBA4A 6611:[DB06616 DB03551] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways GO:0042493| response to drug LYN;PNP;ABCB1;SRC 6612:[DB06616 DB04043] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04043|Carboxymycobactin T LCN2 common genes common pathways GO:0002376| immune system process HCK;SRC;LCN2;LYN GO:0006915| apoptotic process LCN2;ABL1 GO:0045087| innate immune response ABL1;SRC;LCN2;HCK;LYN 6613:[DB06616 DB13940] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13940|2,5-Dimethoxy-4-ethylthioamphetamine HTR2A;HTR2C common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;LYN;CDK2;HCK GO:0016032| viral reproduction HCK;SRC;LYN;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN;HTR2A GO:0042493| response to drug LYN;HTR2A;HTR2C;SRC;ABCB1 GO:0007165| signal transduction LYN;HTR2A;HTR2C;SRC;BCR;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2C;ABL1;MAP2K2;SRC;MAP2K1;HTR2A 6614:[DB06616 DB05073] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05073|SRT501 SIRT1 common genes common pathways GO:0030154| cell differentiation CAMK2G;SIRT1;HCK GO:0071456| cellular response to hypoxia SRC;SIRT1 GO:0006979| response to oxidative stress ABL1;SIRT1 GO:1900034| SIRT1;CAMK2G GO:2000773| negative regulation of cellular senescence SIRT1;ABL1 GO:0031648| protein destabilization SIRT1;SRC GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;SIRT1 GO:0032868| response to insulin stimulus SIRT1;LYN GO:0006915| apoptotic process ABL1;SIRT1 GO:0007179| transforming growth factor beta receptor signaling pathway SIRT1;SRC GO:0070301| cellular response to hydrogen peroxide ABL1;SIRT1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;SIRT1 GO:0042127| regulation of cell proliferation SIRT1;SRC;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;SIRT1 GO:0007275| multicellular organismal development SIRT1;CAMK2G;CDK2 GO:0043065| positive regulation of apoptotic process SRC;SIRT1;ABL1 GO:0042542| response to hydrogen peroxide SRC;SIRT1 GO:0008284| positive regulation of cell proliferation HCK;SIRT1;CDK2;LYN GO:0043066| negative regulation of apoptotic process SIRT1;SRC;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;SIRT1 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K2;SIRT1;MAP2K1 GO:0006281| DNA repair CDK2;SIRT1;ABL1 GO:0006974| response to DNA damage stimulus SIRT1;ABL1;CDK2;LYN GO:0010629| negative regulation of gene expression SIRT1;MAP2K2;MAP2K1 GO:0007346| regulation of mitotic cell cycle MAP2K2;SIRT1;MAP2K1;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;SIRT1 GO:0001934| positive regulation of protein phosphorylation SIRT1;ABL1;LYN GO:0016032| viral reproduction LYN;HCK;SRC;SIRT1 GO:0046628| positive regulation of insulin receptor signaling pathway SRC;SIRT1 GO:0006260| DNA replication SIRT1;CDK2 6615:[DB06616 DB07950] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07950|Indoleacetic acid PLA2G2E;SKP1;CCBL1 common genes common pathways GO:0038095| SKP1;LYN GO:0000086| G2/M transition of mitotic cell cycle CDK2;SKP1;ABCB1 GO:0006954| inflammatory response LYN;PLA2G2E;HCK GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;SKP1;LYN 6616:[DB06616 DB05010] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;GABBR2;GABBR1;LYN 6617:[DB06616 DB00089] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00089|Capromab pendetide FOLH1 common genes common pathways 6618:[DB06616 DB04583] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process ABL1;DHODH;SRC GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0042493| response to drug SRC;ABCB1;DHODH;LYN GO:0014070| response to organic cyclic compound DHODH;LYN 6619:[DB06616 DB01675] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ACAD8 GO:0055114| oxidation-reduction process CYP2C8;ACAD8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ACAD8;ABL1 6620:[DB06616 DB09326] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09326|Ammonia N-13 NAGS;RHCG common genes common pathways 6621:[DB06616 DB00894] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00894|Testolactone CYP19A1 common genes common pathways GO:0060065| uterus development CYP19A1;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP19A1;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 6622:[DB06616 DB07457] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;PDPK1;CDK2;LYN GO:0031295| T cell costimulation LYN;PDPK1;SRC GO:0030168| platelet activation SRC;PDPK1;LYN GO:0006468| protein phosphorylation PDPK1;CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0032869| cellular response to insulin stimulus PDPK1;SRC GO:0046777| protein autophosphorylation CAMK2G;PDPK1;LYN;SRC;BCR;HCK;ABL1 GO:0016477| cell migration PDPK1;SRC GO:0038095| LYN;PDPK1 GO:0018107| peptidyl-threonine phosphorylation PDPK1;CAMK2G;MAP2K1 GO:0035556| intracellular signal transduction CAMK2G;LYN;PDPK1;SRC;BCR GO:0043304| regulation of mast cell degranulation PDPK1;LYN GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;PDPK1;SRC GO:0032148| activation of protein kinase B activity PDPK1;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PDPK1;SRC GO:0030036| actin cytoskeleton organization BCR;ABL1;PDPK1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;PDPK1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;ABL1 6623:[DB06616 DB07970] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways GO:0048013| ephrin receptor signaling pathway SRC;EPHA7;LYN GO:0022407| regulation of cell-cell adhesion EPHA7;SRC GO:0006915| apoptotic process ABL1;EPHA7 GO:0007420| brain development EPHA7;BCR GO:0070372| regulation of ERK1 and ERK2 cascade EPHA7;LYN GO:0006468| protein phosphorylation CAMK2G;EPHA7;LYN;CDK2;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0016310| phosphorylation MAP3K2;LYN;CDK2;EPHA7;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;EPHA7 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;EPHA7 GO:0007399| nervous system development EPHA7;CAMK2G GO:0043065| positive regulation of apoptotic process EPHA7;ABL1;SRC GO:0007275| multicellular organismal development EPHA7;CDK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation LYN;EPHA7;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC 6624:[DB06616 DB07844] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07844|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation LYN;F10 6625:[DB06616 DB07051] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways GO:0007165| signal transduction LYN;PDE4D;BCR;SRC;MAP2K1 GO:0071222| cellular response to lipopolysaccharide PDE4D;BCR;SRC;ABL1 GO:0050900| leukocyte migration LYN;PDE4D;SRC 6626:[DB06616 DB08207] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways GO:0006810| transport ABCB1;TTR 6627:[DB06616 DB02924] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02924|(4R)-limonene 1α,2α-epoxide LCN9 common genes common pathways 6628:[DB06616 DB13995] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13995|Ferric pyrophosphate citrate FTL;FTH1;HBA1;HBB common genes common pathways GO:0007596| blood coagulation LYN;HBB GO:0008285| negative regulation of cell proliferation LYN;FTH1;MAP2K1 GO:0042542| response to hydrogen peroxide SRC;HBB;HBA1 GO:0055114| oxidation-reduction process CYP3A4;FTH1;CYP2C8 6629:[DB06616 DB11572] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11572|Thrombin Alfa F11;F8;F5;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0007165| signal transduction FGG;LYN;MAP2K1;FGA;BCR;SRC;FGB GO:0002376| immune system process HCK;FGA;FGB;SRC;LYN GO:1900026| ABL1;FGB;FGA;FGG GO:0030168| platelet activation LYN;FGG;F8;FGA;SRC;FGB GO:0070374| positive regulation of ERK1 and ERK2 cascade FGG;ABL1;MAP2K2;SRC;FGB;MAP2K1;FGA GO:0007596| blood coagulation FGA;F5;F11;FGB;F13A1;FGG;F13B;F8;LYN GO:2000352| negative regulation of endothelial cell apoptosis ABL1;FGA;FGB;FGG GO:0045087| innate immune response LYN;FGA;HCK;SRC;FGB;ABL1 GO:0002576| platelet degranulation FGG;F8;LYN;FGA;F5;FGB;F13A1 GO:0002250| adaptive immune response FGB;FGA;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;F8 6630:[DB06616 DB06795] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06795|Mafenide CA6 common genes common pathways 6631:[DB06616 DB00447] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A1;SLC15A2;ABCB1 GO:0006810| transport SLC15A1;SLC15A2;ABCB1 6632:[DB06616 DB05854] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05854|CLX-0921 PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;PPARG;CDK2;MAP2K2;SRC;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 GO:0009612| response to mechanical stimulus PPARG;SRC GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0007507| heart development PPARG;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0010033| response to organic substance PPARG;CDK2 GO:0014070| response to organic cyclic compound PPARG;LYN GO:0007165| signal transduction LYN;PPARG;MAP2K1;BCR;SRC GO:0032869| cellular response to insulin stimulus SRC;PPARG 6633:[DB06616 DB00492] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 6634:[DB06616 DB00986] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways GO:0007165| signal transduction CHRM2;LYN;CHRM1;CHRM3;MAP2K1;SRC;BCR GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0008283| cell proliferation SRC;CHRM1;CHRM3 GO:0007399| nervous system development CHRM3;CAMK2G;CHRM1;CHRM2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRM1;HCK GO:0009615| response to virus SRC;CHRM2 6635:[DB06616 DB05443] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0007165| signal transduction LYN;OPRK1;BCR;SRC;MAP2K1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;OPRK1;ABL1 6636:[DB06616 DB05098] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05098|Leptin LEPR common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;LEPR GO:0006909| phagocytosis HCK;LEPR;ABL1 6637:[DB06616 DB00217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;SRC;ADRA2A GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADRA2A;HCK GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;ADRA2B GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;SRC;MAP2K2;MAP2K1 GO:0030168| platelet activation SRC;ADRA2A;ADRA2C;ADRA2B;LYN GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0030335| positive regulation of cell migration LYN;ADRA2A GO:0007165| signal transduction ADRA2C;LYN;ADRA2B;ADRB2;ADRA2A;ADRB3;ADRB1;SRC;BCR;MAP2K1 GO:0006813| potassium ion transport KCNJ1;CDK2 GO:0045453| bone resorption SRC;ADRB2 6638:[DB06616 DB09344] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways GO:0055085| transmembrane transport SLC2A5;SLC2A2;ABCB1 GO:0032869| cellular response to insulin stimulus GCK;SRC GO:0016310| phosphorylation CAMK2G;LYN;CDK2;GCK;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 6639:[DB06616 DB12202] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12202|Zalutumumab EGFR common genes common pathways GO:0006979| response to oxidative stress EGFR;ABL1 GO:0007165| signal transduction EGFR;MAP2K1;SRC;BCR;LYN GO:0070372| regulation of ERK1 and ERK2 cascade LYN;EGFR GO:0016310| phosphorylation MAP2K2;BCR;SRC;MAP2K1;HCK;EGFR;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;EGFR;HCK GO:0030335| positive regulation of cell migration LYN;EGFR GO:0098609| EGFR;SRC GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;EGFR;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:1903800| MAP2K2;MAP2K1;EGFR GO:0000186| activation of MAPKK activity MAP3K2;EGFR GO:0045930| negative regulation of mitotic cell cycle EGFR;ABL1 GO:0046777| protein autophosphorylation LYN;CAMK2G;EGFR;HCK;BCR;SRC;ABL1 GO:0034614| cellular response to reactive oxygen species EGFR;SRC GO:0043406| positive regulation of MAP kinase activity SRC;EGFR GO:0008283| cell proliferation EGFR;SRC GO:0014070| response to organic cyclic compound EGFR;LYN GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;EGFR;MAP2K1;ABL1 GO:0008284| positive regulation of cell proliferation HCK;EGFR;CDK2;LYN GO:0043066| negative regulation of apoptotic process SRC;EGFR;HCK GO:0042327| positive regulation of phosphorylation LYN;EGFR GO:0035556| intracellular signal transduction BCR;SRC;EGFR;CAMK2G;LYN GO:2000145| regulation of cell motility ABL1;EGFR GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0042127| regulation of cell proliferation ABL1;SRC;EGFR GO:0018108| peptidyl-tyrosine phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;EGFR;MAP2K1;LYN GO:0007275| multicellular organismal development CDK2;CAMK2G;EGFR GO:0038128| EGFR;SRC GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC GO:0000165| MAPKKK cascade MAP2K2;EGFR;MAP2K1;CAMK2G GO:0038083| ABL1;HCK;EGFR;SRC;LYN GO:0007173| epidermal growth factor receptor signaling pathway EGFR;SRC;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K2;SRC;MAP2K1;EGFR GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;EGFR 6640:[DB06616 DB00709] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00709|Lamivudine pol;DCK;CMPK1;PGK1;NME1;NME2;PCYT1A;PCYT2;NT5C;ALB;ABCC1;SLC22A6;ABCG2;SLC22A1;SLC22A2;SLC22A3;ABCB1;ABCC4;ABCC3;ABCC2 common genes ABCB1 common pathways GO:0010033| response to organic substance CDK2;ABCC4 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;NME1 GO:0055085| transmembrane transport ABCC2;SLC22A2;ABCG2;ABCC4;ABCB1;ABCC3;SLC22A1;ABCC1;SLC22A6;SLC22A3 GO:0006855| drug transmembrane transport ABCB1;ABCG2;SLC22A2;ABCC2;SLC22A3;ABCC1;SLC22A1;ABCC3 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0014070| response to organic cyclic compound LYN;ABCC4 GO:0006979| response to oxidative stress ABCC2;ABL1 GO:0006810| transport ABCC3;ABCC1;ABCC2;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCC3;ABCG2;ABCB1 GO:0007229| integrin-mediated signaling pathway SRC;HCK;NME2;ABL1 GO:0071456| cellular response to hypoxia SRC;PGK1 GO:0030154| cell differentiation HCK;NME1;CAMK2G GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;NME1;ABL1;NME2;MAP3K2;LYN;CDK2;CMPK1;PGK1;DCK;CAMK2G GO:0002762| negative regulation of myeloid leukocyte differentiation LYN;NME1 GO:0010976| positive regulation of neuron projection development NME1;LYN GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2C8;ABCC4;CYP3A4 GO:0099040| ABCB1 GO:0006355| regulation of transcription, DNA-dependent NME2;ABL1 GO:0042493| response to drug ABCB1;SRC;ABCC4;ABCG2;NME1;ABCC2;ABCC1;LYN GO:0010629| negative regulation of gene expression NME1;MAP2K2;MAP2K1 GO:0006629| lipid metabolic process PCYT1A;CYP3A4;PCYT2 GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;MAP2K2;NME1 GO:0007399| nervous system development CAMK2G;NME1 GO:0007155| cell adhesion ABL1;NME2;SRC;HCK GO:0043066| negative regulation of apoptotic process SRC;HCK;NME2;ALB GO:0006897| endocytosis ABL1;NME1 GO:0071398| cellular response to fatty acid NME1;SRC GO:0071222| cellular response to lipopolysaccharide ABL1;ABCC2;BCR;SRC GO:0002576| platelet degranulation LYN;ALB;ABCC4 GO:0032496| response to lipopolysaccharide ABCC2;BCR GO:1901529| ABCB1 6641:[DB06616 DB01090] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CHRNA10 GO:0007165| signal transduction CHRNB4;LYN;SRC;CHRNA3;BCR;MAP2K1;CHRNA10 GO:0042472| inner ear morphogenesis BCR;CHRNA10 GO:0042127| regulation of cell proliferation ABL1;CHRNA10;SRC GO:0007399| nervous system development CAMK2G;CHRNA3 GO:0006816| calcium ion transport CAMK2G;CHRNA10 6642:[DB06616 DB12140] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;TNF GO:0043407| negative regulation of MAP kinase activity LYN;IL1B GO:0070301| cellular response to hydrogen peroxide ABL1;IL6 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;IL6;IL1B GO:0010033| response to organic substance TNF;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0050766| positive regulation of phagocytosis IL1B;BCR;TNF GO:0010628| positive regulation of gene expression TNF;IL1B;IL6;MAP2K1;SRC GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;TNF GO:0000187| activation of MAPK activity IL1B;MAP2K1;MAP2K2;TNF;MAP3K2 GO:0006915| apoptotic process ABL1;IL1B GO:0031175| neuron projection development IL6;LYN GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0007165| signal transduction IL1B;BCR;SRC;MAP2K1;LYN GO:0051222| positive regulation of protein transport SRC;TNF GO:0070372| regulation of ERK1 and ERK2 cascade LYN;IL1B GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0030168| platelet activation LYN;SRC;IL6 GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0030335| positive regulation of cell migration LYN;IL1B GO:0009743| response to carbohydrate stimulus IL1B;LYN GO:0019221| cytokine-mediated signaling pathway IL6;HCK;IL1B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;IL6;LYN GO:0000165| MAPKKK cascade CAMK2G;TNF;MAP2K2;MAP2K1;IL1B GO:0071803| positive regulation of podosome assembly SRC;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0006954| inflammatory response LYN;TNF;IL1B;IL6;HCK GO:0050900| leukocyte migration LYN;TNF;IL1B;SRC GO:0001934| positive regulation of protein phosphorylation LYN;TNF;ABL1;IL1B GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TNF GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;IL6;SRC;MAP2K2;IL1B;MAP3K2;TNF;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;TNF GO:0071260| cellular response to mechanical stimulus MAP3K2;IL1B GO:0043065| positive regulation of apoptotic process TNF;SRC;IL6;ABL1 GO:0050727| regulation of inflammatory response LYN;TNF;HCK GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;IL6;IL1B GO:0009615| response to virus TNF;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;IL6;ABL1;TNF GO:0043066| negative regulation of apoptotic process SRC;HCK;IL6 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;IL1B;LYN;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IL1B;ABL1 GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL6;LYN GO:0042127| regulation of cell proliferation ABL1;SRC;TNF GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0032496| response to lipopolysaccharide BCR;IL1B 6643:[DB06616 DB08520] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway FKBP1A;HCK GO:0001933| negative regulation of protein phosphorylation FKBP1A;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;SRC 6644:[DB06616 DB01291] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways GO:0071902| positive regulation of protein serine/threonine kinase activity ADRB2;MAP2K1;SRC;MAP2K2 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0007165| signal transduction BCR;SRC;ADRB1;MAP2K1;ADRB2;LYN GO:0045453| bone resorption SRC;ADRB2 6645:[DB06616 DB02054] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02054|Gabaculine OAT common genes common pathways 6646:[DB06616 DB01646] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01646|N-Acetylmethionine RHO common genes common pathways GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;RHO;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;RHO 6647:[DB06616 DB00183] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00183|Pentagastrin CCKBR;BCHE common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCKBR GO:0007165| signal transduction BCR;SRC;MAP2K1;CCKBR;LYN GO:0008283| cell proliferation SRC;CCKBR GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;CCKBR;HCK GO:0042493| response to drug BCHE;LYN;ABCB1;SRC 6648:[DB06616 DB02884] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;ZFY GO:0048872| homeostasis of number of cells BCR;ZFY GO:0006355| regulation of transcription, DNA-dependent ZFY;ABL1 GO:0009791| post-embryonic development ZFY;ABL1 6649:[DB06616 DB08575] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways 6650:[DB06616 DB02852] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02852|Domoic Acid GRIK2 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport GRIK2;ABCB1 6651:[DB06616 DB08085] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;THRB GO:0006355| regulation of transcription, DNA-dependent ABL1;THRB GO:0045892| negative regulation of transcription, DNA-dependent THRB;SRC 6652:[DB06616 DB07802] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07802|3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE CSNK2A1 common genes common pathways GO:1901796| CSNK2A1;CDK2 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CSNK2A1 GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0007165| signal transduction CSNK2A1;LYN;BCR;SRC;MAP2K1 GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;CSNK2A1;MAP3K2;CDK2;LYN;CAMK2G GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;CSNK2A1;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0007049| cell cycle SRC;CDK2;CSNK2A1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CSNK2A1;MAP2K1 GO:0006915| apoptotic process ABL1;CSNK2A1 6653:[DB06616 DB08356] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways GO:0006468| protein phosphorylation ABL1;HCK;PDK4;MAP2K1;SRC;MAP2K2;BCR;CDK2;LYN;CAMK2G;MAP3K2 GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;PDK4;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:2000811| negative regulation of anoikis PDK4;SRC GO:0045124| regulation of bone resorption SRC;PDK4 GO:0071398| cellular response to fatty acid SRC;PDK4 6654:[DB06616 DB09149] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09149|Florbetapir (18F) APP common genes common pathways GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;APP;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP GO:0006979| response to oxidative stress APP;ABL1 GO:0030900| forebrain development SRC;APP GO:0031175| neuron projection development LYN;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;MAP2K2;SRC;MAP2K1;ABL1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;APP;MAP3K2 GO:0006915| apoptotic process APP;ABL1 GO:1900272| ABL1;APP GO:0010628| positive regulation of gene expression APP;MAP2K1;SRC GO:0008285| negative regulation of cell proliferation LYN;APP;MAP2K1 GO:0045931| positive regulation of mitotic cell cycle ABL1;APP GO:0043393| regulation of protein binding APP;SRC GO:0043065| positive regulation of apoptotic process APP;ABL1;SRC GO:0002576| platelet degranulation LYN;APP GO:0006897| endocytosis ABL1;APP GO:0042327| positive regulation of phosphorylation LYN;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;CDK2 GO:0007155| cell adhesion APP;ABL1;SRC;HCK GO:0045087| innate immune response ABL1;HCK;SRC;LYN;APP GO:0007399| nervous system development CAMK2G;APP GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;APP GO:1901216| APP;ABL1 GO:0050885| neuromuscular process controlling balance APP;ABL1;BCR GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;LYN;SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade APP;SRC 6655:[DB06616 DB00542] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0043200| response to amino acid stimulus MTHFR;LYN GO:0055085| transmembrane transport SLC15A1;SLC15A2;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0070555| response to interleukin-1 SRC;MTHFR GO:0042493| response to drug LYN;MTHFR;ABCB1;SRC GO:0055114| oxidation-reduction process CYP3A4;MTHFR;CYP2C8 6656:[DB06616 DB00742] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00742|Mannitol ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug ABCB1;SRC;LYN GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0055085| transmembrane transport ABCB1 6657:[DB06616 DB13261] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug LYN;CYP1A2;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 6658:[DB06616 DB01790] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways GO:0007507| heart development MAP2K1;PRKAR1A GO:0035556| intracellular signal transduction LYN;CAMK2G;PRKAR1A;BCR;SRC GO:0001932| regulation of protein phosphorylation MAP2K1;PRKAR1A;LYN GO:0007596| blood coagulation LYN;PRKAR1A 6659:[DB06616 DB08565] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 6660:[DB06616 DB03471] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03471|6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid PLA2G2A common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;PLA2G2A;ABL1 GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 6661:[DB06616 DB07749] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways 6662:[DB06616 DB09120] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TRPV1 GO:0006810| transport ABCB1;TRPV1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP2E1;CYP2C9;CYP3A4;CYP1A2 GO:0043434| response to peptide hormone stimulus TRPV1;LYN GO:0034605| cellular response to heat TRPV1;LYN GO:0097267| CYP2C8;CYP2C19;CYP1A2;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2C19;CYP2C8 GO:0065009| regulation of molecular function CAMK2G;TRPV1 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP1A2;CYP2C8 GO:0055085| transmembrane transport ABCB1;TRPV1 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2C19 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;CDK2 GO:0006629| lipid metabolic process CYP1A2;CYP2C9;CYP3A4;TRPV1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0043065| positive regulation of apoptotic process ABL1;SRC;TRPV1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP2E1;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2E1;CYP1A2;CYP2C19;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4;CYP2C9;CYP1A2 GO:0042493| response to drug LYN;CYP2E1;CYP1A2;SRC;ABCB1 GO:0006954| inflammatory response LYN;HCK;TRPV1 GO:0006816| calcium ion transport CAMK2G;TRPV1 6663:[DB06616 DB06116] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06116|Eldelumab CXCL10 common genes common pathways GO:0006954| inflammatory response HCK;LYN;CXCL10 GO:0008284| positive regulation of cell proliferation HCK;CXCL10;CDK2;LYN GO:0006935| chemotaxis CXCL10;MAP2K1 GO:0009615| response to virus SRC;CXCL10 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;CXCL10 GO:0032496| response to lipopolysaccharide BCR;CXCL10 GO:0042127| regulation of cell proliferation CXCL10;SRC;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;CXCL10 GO:0007165| signal transduction LYN;CXCL10;MAP2K1;BCR;SRC GO:0034605| cellular response to heat CXCL10;LYN GO:0030335| positive regulation of cell migration LYN;CXCL10 6664:[DB06616 DB05848] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;IL12B;SRC GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL12B;LYN GO:0007050| cell cycle arrest ABL1;IL12B;MAP2K1 GO:0010033| response to organic substance IL12B;CDK2 GO:0016477| cell migration SRC;IL12B GO:0008283| cell proliferation IL12B;SRC GO:0045785| positive regulation of cell adhesion IL12B;SRC 6665:[DB06616 DB04036] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04036|Coenzyme a Persulfide IVD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;IVD;CYP2C8 6666:[DB06616 DB07240] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 6667:[DB06616 DB00143] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes CYP3A4 common pathways GO:0032496| response to lipopolysaccharide BCR;MGST1;ABCC2;MGST2 GO:0046483| heterocycle metabolic process CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0034599| cellular response to oxidative stress GPX1;GSTP1;GPX2;ABL1;GSR;GPX3;GPX5;GPX7;GPX8 GO:0042737| drug catabolic process CYP3A4 GO:0007275| multicellular organismal development CAMK2G;CDK2;GPX4 GO:0071222| cellular response to lipopolysaccharide GSTP1;BCR;SRC;ABCC2;ABL1 GO:0042542| response to hydrogen peroxide GPX1;GLRX2;SRC GO:0050727| regulation of inflammatory response LYN;GGT1;HCK GO:0002576| platelet degranulation ABCC4;LYN GO:0043065| positive regulation of apoptotic process ABL1;SRC;MMP9 GO:0043066| negative regulation of apoptotic process AKR1B1;MMP9;GLO1;SRC;GPX1;HCK;GSTP1 GO:0006805| xenobiotic metabolic process MGST2;GGT1;CYP3A4;GSTA4;GSTP1;GSTO2;MGST3;MGST1;CYP2C8 GO:0007399| nervous system development GSS;CAMK2G GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;GPX5;MGST2;MGST3;GPX1;HPGDS GO:0006355| regulation of transcription, DNA-dependent ABL1;GLRX2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;SRC;ABCC4;MGST1;ABCC2;ABCC1;LYN GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0031667| response to nutrient levels SRC;GSTP1;GSS GO:0050900| leukocyte migration SRC;MMP9;LYN GO:0008209| androgen metabolic process CYP3A4 GO:0001934| positive regulation of protein phosphorylation MMP9;LYN;ABL1 GO:0055114| oxidation-reduction process ABCC4;GSTO2;GLRX2;GPX1;TXNDC12;MGST1;CYP2C8;GSR;GPX6;GSTK1;GPX2;GPX4;GLRX;GPX7;GPX8;GPX3;GPX5;AKR1B1;CYP3A4;GSTO1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;MMP9 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0030335| positive regulation of cell migration LYN;MMP9 GO:0032869| cellular response to insulin stimulus SRC;GSTP1 GO:0030154| cell differentiation CAMK2G;TXNDC12;GLRX2;HCK GO:0006810| transport ABCC1;ABCC3;ABCB1;ABCC5;ABCC2 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCC3 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0006979| response to oxidative stress GPX2;ABL1;GPX6;ABCC2;GPX1;GSS;GPX3;GPX5;GPX7;GPX8;GPX4 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0007165| signal transduction LYN;BCR;HPGDS;SRC;MAP2K1 GO:0070372| regulation of ERK1 and ERK2 cascade LYN;GSTP1 GO:0008283| cell proliferation GPX1;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway GSTP1;SRC GO:0009636| response to toxin GSTP1;GPX1;LYN GO:0014070| response to organic cyclic compound ABCC4;LYN GO:0002933| CYP2C8;CYP3A4 GO:0043200| response to amino acid stimulus LYN;GSS;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0055085| transmembrane transport ABCC2;ABCC5;ABCC4;ABCB1;ABCC3;ABCC1 GO:0036378| CYP3A4 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1;ABCC3 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;GSTP1;MAP2K1 GO:0006915| apoptotic process ABL1;GLRX2;GPX1 GO:0034614| cellular response to reactive oxygen species MMP9;SRC GO:0042359| vitamin D metabolic process CYP3A4 GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0048013| ephrin receptor signaling pathway MMP9;LYN;SRC GO:0010033| response to organic substance CDK2;AKR1B1;ABCC4;GLRX2 6668:[DB06616 DB03466] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03466|BMS184394 RARG common genes common pathways GO:0060324| face development RARG;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ABL1;RARG GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;RARG GO:0043065| positive regulation of apoptotic process ABL1;RARG;SRC GO:0043066| negative regulation of apoptotic process RARG;HCK;SRC GO:0071300| cellular response to retinoic acid LYN;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;CDK2 GO:0010628| positive regulation of gene expression RARG;MAP2K1;SRC GO:0008285| negative regulation of cell proliferation RARG;MAP2K1;LYN GO:0001843| neural tube closure ABL1;RARG 6669:[DB06616 DB04834] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04834|Rapacuronium CHRM2 common genes common pathways GO:0009615| response to virus SRC;CHRM2 GO:0007399| nervous system development CHRM2;CAMK2G GO:0007165| signal transduction LYN;CHRM2;MAP2K1;BCR;SRC 6670:[DB06616 DB03176] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03176|KB-141 THRB;THRA common genes common pathways GO:0030878| thyroid gland development THRA;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent THRA;SRC;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;THRB GO:0030218| erythrocyte differentiation THRA;LYN GO:0006355| regulation of transcription, DNA-dependent THRA;THRB;ABL1 6671:[DB06616 DB01785] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0008202| steroid metabolic process CYP3A4;IDI1;CYP2C8;FDPS GO:0016032| viral reproduction LYN;SRC;FDPS;HCK GO:0006629| lipid metabolic process IDI1;FDPS;CYP3A4 6672:[DB06616 DB14039] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14039|Erenumab CALCRL common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CALCRL GO:0006816| calcium ion transport CAMK2G;CALCRL GO:0050728| negative regulation of inflammatory response CALCRL;BCR GO:0007507| heart development MAP2K1;CALCRL GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;CALCRL 6673:[DB06616 DB03683] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MMP9;SRC GO:0001934| positive regulation of protein phosphorylation ABL1;MMP9;LYN GO:0050900| leukocyte migration LYN;MMP9;SRC GO:0043066| negative regulation of apoptotic process HCK;SRC;MMP9 GO:0043065| positive regulation of apoptotic process MMP9;ABL1;SRC GO:0048013| ephrin receptor signaling pathway LYN;MMP9;SRC GO:0034614| cellular response to reactive oxygen species SRC;MMP9 GO:0030335| positive regulation of cell migration LYN;MMP9 6674:[DB06616 DB03393] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways GO:0050900| leukocyte migration LYN;PPIA;SRC GO:0016032| viral reproduction HCK;SRC;LYN;PPIA 6675:[DB06616 DB01025] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways GO:0050663| cytokine secretion S100A13;S100A12;LYN GO:0008283| cell proliferation FGF1;SRC GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;MAP3K2;FGF1 GO:0043406| positive regulation of MAP kinase activity FGF1;S100A12;SRC GO:0030335| positive regulation of cell migration LYN;FGF1 GO:0034605| cellular response to heat FGF1;LYN GO:0010595| positive regulation of endothelial cell migration FGF1;ABL1 GO:0030154| cell differentiation HCK;FGF1;CAMK2G GO:0002376| immune system process S100A12;LYN;SRC;HCK GO:1902533| FGF1;SRC GO:0065009| regulation of molecular function IL3;CAMK2G GO:0007165| signal transduction BCR;SRC;MAP2K1;FGF1;LYN GO:0001934| positive regulation of protein phosphorylation FGF1;LYN;ABL1 GO:0051602| response to electrical stimulus S100A13;SRC GO:0006954| inflammatory response S100A12;LYN;HCK GO:0000165| MAPKKK cascade FGF1;CAMK2G;IL3;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;SRC GO:0019221| cytokine-mediated signaling pathway HCK;IL3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;IL3;SRC;LYN GO:0007275| multicellular organismal development CDK2;FGF1;CAMK2G GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL3;LYN GO:0018108| peptidyl-tyrosine phosphorylation LYN;FGF1;HCK;MAP2K1;IL3;SRC;BCR;MAP2K2;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;S100A13;S100A12 GO:0006805| xenobiotic metabolic process CYP2C8;S100A12;CYP3A4 GO:0008284| positive regulation of cell proliferation HCK;IL3;S100A13;CDK2;LYN;FGF1 GO:0008360| regulation of cell shape HCK;S100A13 GO:0032148| activation of protein kinase B activity SRC;FGF1 GO:0045087| innate immune response S100A12;LYN;SRC;HCK;ABL1 GO:0007399| nervous system development CAMK2G;IL3 6676:[DB06616 DB03744] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways 6677:[DB06616 DB01613] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways GO:0035556| intracellular signal transduction LYN;CAMK2G;NPR1;SRC;NPR2;BCR GO:0043114| regulation of vascular permeability BCR;SRC;NPR1 GO:0006468| protein phosphorylation MAP3K2;CDK2;LYN;CAMK2G;HCK;NPR1;MAP2K1;SRC;BCR;NPR2;MAP2K2;ABL1 6678:[DB06616 DB01413] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A2;SLC22A5;SLC15A1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 6679:[DB06616 DB02016] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02016|R048-8071 LSS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;LSS 6680:[DB06616 DB02211] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02211|N-Methyl-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0042493| response to drug LYN;MAOB;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;MAOB;CYP3A4 GO:0009636| response to toxin LYN;MAOB 6681:[DB06616 DB01878] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01878|Benzophenone ESR1;ESR2 common genes common pathways GO:0007165| signal transduction LYN;ESR1;ESR2;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0060065| uterus development ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2;ESR1 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;ESR2;MAP3K2;ESR1;CDK2 GO:0008209| androgen metabolic process CYP3A4;ESR1 6682:[DB06616 DB05383] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05383|Pimagedine NOS2;AKR1B1;TIMP3;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4;AKR1B1;CYP2C8 GO:0010629| negative regulation of gene expression NOS2;MAP2K1;MAP2K2 GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0042127| regulation of cell proliferation NOS2;ABL1;SRC GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1;NOS2 GO:0002576| platelet degranulation LYN;TIMP3 GO:0043066| negative regulation of apoptotic process HCK;SRC;AKR1B1 GO:0055085| transmembrane transport ABCB1;SLC22A2 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1;TIMP3 GO:0010033| response to organic substance AKR1B1;CDK2;TIMP3 6683:[DB06616 DB03070] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;IMPDH2 6684:[DB06616 DB09212] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042493| response to drug LYN;PTGS2;SRC;ABCB1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC;PTGS1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0008284| positive regulation of cell proliferation HCK;PTGS2;LYN;CDK2 GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 6685:[DB06616 DB06089] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways GO:0007399| nervous system development CAMK2G;KCNQ2 GO:0042472| inner ear morphogenesis KCNQ4;BCR GO:0006813| potassium ion transport KCNQ1;KCNQ2;KCNQ5;KCNQ4;CDK2;KCNQ3 GO:0072358| cardiovascular system development ABL1;KCNQ1 GO:0055085| transmembrane transport KCNQ4;KCNQ3;ABCB1;KCNQ1;KCNQ5;KCNQ2 6686:[DB06616 DB00012] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00012|Darbepoetin alfa EPOR common genes common pathways GO:0019221| cytokine-mediated signaling pathway HCK;EPOR GO:0007507| heart development MAP2K1;EPOR GO:0007165| signal transduction SRC;BCR;MAP2K1;LYN;EPOR GO:0007420| brain development BCR;EPOR 6687:[DB06616 DB03929] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0009636| response to toxin SLC6A14;LYN GO:0055085| transmembrane transport SLC16A10;ABCB1;SLC6A14 GO:0048013| ephrin receptor signaling pathway GRIN1;LYN;SRC GO:0030335| positive regulation of cell migration LYN;SERPINB3 GO:0006810| transport SLC6A14;ABCB1 GO:0065009| regulation of molecular function CAMK2G;GRIN1 GO:0006816| calcium ion transport CAMK2G;GRIN1 GO:0000165| MAPKKK cascade GRIN1;CAMK2G;MAP2K1;MAP2K2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;SERPINB3 GO:0043065| positive regulation of apoptotic process SRC;ABL1;GRIN1 6688:[DB06616 DB08100] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0006810| transport ABCB1;TTR 6689:[DB06616 DB04523] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04523|Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK 6690:[DB06616 DB04673] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04673|4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0030335| positive regulation of cell migration F10;LYN GO:0007596| blood coagulation F10;LYN 6691:[DB06616 DB04924] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04924|Itopride DRD2;ACHE common genes common pathways GO:0048678| response to axon injury LYN;DRD2 GO:0007399| nervous system development ACHE;CAMK2G GO:0007155| cell adhesion ABL1;HCK;SRC;ACHE GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;DRD2 GO:0042493| response to drug LYN;DRD2;SRC;ABCB1 GO:0006260| DNA replication ACHE;CDK2 GO:0030900| forebrain development SRC;DRD2 GO:0007165| signal transduction LYN;MAP2K1;BCR;DRD2;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;DRD2;SRC;MAP2K2;ABL1 GO:0009636| response to toxin DRD2;LYN GO:0008283| cell proliferation ACHE;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;LYN GO:0030336| negative regulation of cell migration BCR;DRD2 6692:[DB06616 DB12455] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes ABCB1 common pathways GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation ALB;LYN GO:0042493| response to drug LYN;SRC;ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 6693:[DB06616 DB04322] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04322|LY249543 MTHFD1 common genes common pathways GO:0001843| neural tube closure MTHFD1;ABL1 GO:0007507| heart development MTHFD1;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MTHFD1 6694:[DB06616 DB04575] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04575|Quinestrol ESR1 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;ESR1 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0060065| uterus development ESR1;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;ESR1;MAP3K2;MAP2K1;SRC;MAP2K2 6695:[DB06616 DB06350] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06350|Elinogrel P2RY12 common genes common pathways GO:0051924| regulation of calcium ion transport CAMK2G;P2RY12 GO:0030168| platelet activation LYN;P2RY12;SRC GO:0007165| signal transduction P2RY12;MAP2K1;BCR;SRC;LYN GO:0065009| regulation of molecular function CAMK2G;P2RY12 GO:0007596| blood coagulation LYN;P2RY12 6696:[DB06616 DB08039] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways GO:0000165| MAPKKK cascade CALM1;MAP2K1;MAP2K2;CAMK2D;CAMK2G GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0002576| platelet degranulation LYN;CALM1 GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;CAMK2D GO:0007399| nervous system development CAMK2D;CAMK2G GO:0051259| protein oligomerization CAMK2D;CAMK2G GO:1901897| CAMK2D;CAMK2G GO:0071902| positive regulation of protein serine/threonine kinase activity CALM1;MAP2K1;MAP2K2;SRC GO:0046777| protein autophosphorylation LYN;CAMK2D;CAMK2G;ABL1;HCK;SRC;BCR GO:0038095| LYN;CALM1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CAMK2D;MAP2K1 GO:0055085| transmembrane transport CALM1;ABCB1 GO:1900034| CAMK2G;CAMK2D GO:0060333| interferon-gamma-mediated signaling pathway HCK;CAMK2G;CAMK2D GO:0016310| phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;CAMK2D;MAP3K2 GO:0006468| protein phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN;CDK2;CAMK2D;CAMK2G;MAP3K2 GO:0030154| cell differentiation HCK;CAMK2G;CAMK2D 6697:[DB06616 DB13985] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways GO:0008285| negative regulation of cell proliferation SSTR5;SSTR4;MAP2K1;SSTR1;LYN;SSTR3;SSTR2 GO:0016477| cell migration SSTR4;SRC GO:0030900| forebrain development SSTR2;SSTR3;SSTR1;SSTR4;SRC GO:0007165| signal transduction SSTR1;LYN;SSTR3;SSTR2;SRC;SSTR5;BCR;MAP2K1;SSTR4 6698:[DB06616 DB04615] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0006260| DNA replication CDK2;ACHE GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion ABL1;SRC;HCK;ACHE 6699:[DB06616 DB01567] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;SRC;ABCB1;LYN GO:0007420| brain development BCR;GABRA5 GO:0007165| signal transduction MAP2K1;SRC;BCR;GABRB3;GABRA5;GABRB1;GABRE;GABRR2;LYN;GABRP;GABRD GO:0006810| transport GABRB3;ABCB1;GABRA1;GABRB2;GABRD;GABRR1;GABRA3;GABRB1;GABRA5;GABRG2;GABRR2 GO:0009791| post-embryonic development GABRG2;ABL1 GO:0009636| response to toxin GABRB1;LYN 6700:[DB06616 DB08323] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08323|3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE IGHG2 common genes common pathways GO:0002376| immune system process SRC;HCK;IGHG2;LYN GO:0050853| B cell receptor signaling pathway ABL1;LYN;IGHG2 GO:0045087| innate immune response IGHG2;LYN;SRC;HCK;ABL1 GO:0038096| SRC;HCK;ABL1;IGHG2;LYN GO:0002250| adaptive immune response IGHG2;LYN 6701:[DB06616 DB04376] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04376|13-Acetylphorbol PRKCD common genes common pathways GO:0090398| cellular senescence PRKCD;MAP2K1 GO:0050728| negative regulation of inflammatory response BCR;PRKCD GO:0038096| ABL1;SRC;HCK;LYN;PRKCD GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;PRKCD;LYN GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;PRKCD;LYN GO:0035556| intracellular signal transduction BCR;SRC;PRKCD;LYN;CAMK2G GO:0018105| peptidyl-serine phosphorylation SRC;CAMK2G;CDK2;PRKCD GO:0006915| apoptotic process PRKCD;ABL1 GO:0018107| peptidyl-threonine phosphorylation CAMK2G;PRKCD;MAP2K1 GO:0042100| B cell proliferation PRKCD;ABL1 GO:0007049| cell cycle SRC;PRKCD;CDK2 GO:0043407| negative regulation of MAP kinase activity LYN;PRKCD GO:0070301| cellular response to hydrogen peroxide ABL1;PRKCD GO:0016310| phosphorylation PRKCD;MAP3K2;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0030168| platelet activation LYN;PRKCD;SRC GO:0006468| protein phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2;PRKCD GO:0060333| interferon-gamma-mediated signaling pathway CAMK2G;PRKCD;HCK GO:0032956| regulation of actin cytoskeleton organization PRKCD;ABL1 GO:0016572| histone phosphorylation CDK2;PRKCD GO:0007165| signal transduction PRKCD;LYN;BCR;SRC;MAP2K1 6702:[DB06616 DB00771] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00771|Clidinium CHRM1 common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;CHRM1 GO:0006464| protein modification process CHRM1;ABL1 GO:0008283| cell proliferation SRC;CHRM1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRM1;HCK GO:0007399| nervous system development CAMK2G;CHRM1 6703:[DB06616 DB05468] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05468|R411 ITGA4 common genes common pathways GO:0007155| cell adhesion HCK;SRC;ITGA4;ABL1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;ITGA4;SRC GO:0050900| leukocyte migration SRC;ITGA4;LYN GO:0007229| integrin-mediated signaling pathway SRC;ITGA4;HCK;ABL1 6704:[DB06616 DB07021] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways GO:0031295| T cell costimulation SRC;DPP4;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;DPP4;HCK GO:0007155| cell adhesion DPP4;SRC;HCK;ABL1 GO:0043542| endothelial cell migration ABL1;DPP4 6705:[DB06616 DB07226] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07226|N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE WEE1 common genes common pathways GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;LYN;CDK2;WEE1;MAP3K2 GO:0006468| protein phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;CDK2;LYN;WEE1 GO:0007049| cell cycle CDK2;WEE1;SRC GO:0000086| G2/M transition of mitotic cell cycle CDK2;WEE1;ABCB1 GO:0051726| regulation of cell cycle WEE1;BCR;SRC;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation LYN;WEE1;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0051301| cell division CDK2;WEE1 GO:0000082| G1/S transition of mitotic cell cycle CDK2;WEE1;CAMK2G GO:0000278| mitotic cell cycle WEE1;ABL1 6706:[DB06616 DB06367] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06367|Relacatib CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 6707:[DB06616 DB07202] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways GO:2000249| regulation of actin cytoskeleton reorganization CSF1R;ABL1 GO:0043066| negative regulation of apoptotic process SRC;CSF1R;HCK GO:0008284| positive regulation of cell proliferation CDK2;LYN;CSF1R;HCK GO:0045124| regulation of bone resorption CSF1R;SRC GO:0008360| regulation of cell shape CSF1R;HCK GO:0045087| innate immune response LYN;SRC;CSF1R;HCK;ABL1 GO:0007275| multicellular organismal development CSF1R;CAMK2G;CDK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein CSF1R;LYN GO:0018108| peptidyl-tyrosine phosphorylation LYN;CSF1R;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 GO:0006954| inflammatory response CSF1R;HCK;LYN GO:0019221| cytokine-mediated signaling pathway HCK;CSF1R GO:0001934| positive regulation of protein phosphorylation LYN;CSF1R;ABL1 GO:0002376| immune system process HCK;CSF1R;SRC;LYN GO:0030097| hemopoiesis LYN;CSF1R GO:0007165| signal transduction LYN;CSF1R;MAP2K1;BCR;SRC GO:0030335| positive regulation of cell migration CSF1R;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;CSF1R;LYN GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;CSF1R;MAP2K1;ABL1 GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CSF1R;CAMK2G;LYN;CDK2;MAP3K2 GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;CSF1R GO:0046777| protein autophosphorylation CAMK2G;LYN;BCR;SRC;CSF1R;HCK;ABL1 GO:0008285| negative regulation of cell proliferation LYN;CSF1R;MAP2K1 GO:0007411| axon guidance SRC;CSF1R GO:0008283| cell proliferation CSF1R;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;CSF1R;MAP2K1;ABL1 6708:[DB06616 DB08791] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways GO:0007165| signal transduction LYN;MET;MAP2K1;BCR;SRC GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;MET;CDK2;LYN;CAMK2G GO:0016310| phosphorylation MET;MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;MET;HCK GO:0008283| cell proliferation MET;SRC GO:0035635| entry of bacterium into host cell MET;SRC GO:0018108| peptidyl-tyrosine phosphorylation MET;LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MET GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;MET;CAMK2G 6709:[DB06616 DB08398] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08398|2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine ESR1;NCOA2 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR1;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;ESR1;MAP2K1;MAP2K2;SRC GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;ESR1;MAP3K2 GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0060065| uterus development SRC;ESR1 6710:[DB06616 DB00107] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0014070| response to organic cyclic compound OXT;LYN;OXTR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OXT;OXTR GO:0043434| response to peptide hormone stimulus LYN;OXTR;OXT GO:0007165| signal transduction SRC;BCR;MAP2K1;OXTR;LYN;OXT GO:0042493| response to drug OXTR;LYN;ABCB1;SRC GO:0051602| response to electrical stimulus OXT;SRC GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;OXTR GO:0007507| heart development MAP2K1;OXT;OXTR 6711:[DB06616 DB00177] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00177|Valsartan AGTR1;CYP2C9;ALB;SLCO1B3;SLCO1B1 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0007165| signal transduction MAP2K1;SRC;BCR;AGTR1;LYN GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ABL1 GO:0055085| transmembrane transport ABCB1;SLCO1B1;SLCO1B3 GO:0050727| regulation of inflammatory response LYN;HCK;AGTR1 GO:0002576| platelet degranulation LYN;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0042127| regulation of cell proliferation SRC;ABL1;AGTR1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 6712:[DB06616 DB09214] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1;CYP2C8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;SRC;PTGS1 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 6713:[DB06616 DB08292] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08292|(5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0038096| HCK;SRC;ABL1;HSP90AB1;LYN GO:0042493| response to drug LYN;HSP90AB1;ABCB1;SRC GO:0006805| xenobiotic metabolic process HSP90AB1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process HCK;SRC;HSP90AB1 GO:0045597| positive regulation of cell differentiation MAP2K1;HSP90AB1 GO:0071902| positive regulation of protein serine/threonine kinase activity HSP90AB1;MAP2K1;MAP2K2;SRC GO:0010033| response to organic substance CDK2;HSP90AB1 GO:1900034| HSP90AB1;CAMK2G 6714:[DB06616 DB00659] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0050885| neuromuscular process controlling balance GRIN2C;ABL1;BCR GO:0042493| response to drug GABRG3;GRIN2A;ABCB1;SRC;LYN GO:1901216| GRIN2B;ABL1 GO:0051924| regulation of calcium ion transport GRIN3B;CAMK2G GO:0000165| MAPKKK cascade GRIN2A;MAP2K1;MAP2K2;CAMK2G;GRIN2B;GRIN2C;GRIN2D;GRIN1 GO:0006816| calcium ion transport GRIN2A;GRIN1;GRIN3A;CAMK2G GO:0001932| regulation of protein phosphorylation MAP2K1;LYN;GRM5 GO:0043065| positive regulation of apoptotic process GRIN1;SRC;GRIN2A;ABL1 GO:0055085| transmembrane transport SLC36A1;ABCB1 GO:0009636| response to toxin LYN;GABRB1 GO:0048013| ephrin receptor signaling pathway SRC;LYN;GRIN2B;GRIN1 GO:0009791| post-embryonic development ABL1;GABRG2 GO:0006810| transport ABCB1;GRIN2A;GABRB3;GABRA3;GABRG2;GABRA5;GABRB1;GRIN2C;GABRA1;GRIN2B;GABRD;GABRB2;GABRA6;GABRA4 GO:0007417| central nervous system development SRC;LYN;GABRA4 GO:0007420| brain development GABRA5;BCR GO:0007165| signal transduction GABRD;GABRA6;GABRP;LYN;GABRE;GABRQ;GRM5;GABRA5;GABRB1;GABRB3;SRC;BCR;MAP2K1 GO:0065009| regulation of molecular function GRIN2A;CAMK2G;GRIN2B;GRIN2C;GRIN2D;GRIN1 6715:[DB06616 DB05540] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways GO:0002376| immune system process LYN;ADSS;HCK;ADSSL1;SRC GO:0006979| response to oxidative stress SLC7A11;ABL1 GO:0007420| brain development SLC7A11;BCR GO:0009636| response to toxin LYN;SLC7A11 GO:0050900| leukocyte migration LYN;SLC7A11;SRC 6716:[DB06616 DB03331] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03331|N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;GAPDHS;CYP3A4 6717:[DB06616 DB09043] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09043|Albiglutide GLP1R common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;ABL1 GO:0007165| signal transduction GLP1R;LYN;BCR;SRC;MAP2K1 6718:[DB06616 DB00239] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0010628| positive regulation of gene expression NR1I2;MAP2K1;SRC GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1I2 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;NR1I2;CYP3A4 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction MAP2K1;SRC;BCR;NR1I2;LYN GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8;CYP2C19 GO:0006355| regulation of transcription, DNA-dependent NR1I2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;MAP3K2;NR1I2;CDK2 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;NR1I2;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 6719:[DB06616 DB00666] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;GNRHR GO:0007165| signal transduction GNRHR2;MAP2K1;SRC;BCR;GNRHR;LYN 6720:[DB06616 DB07697] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07697|1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine PKM common genes common pathways GO:0016310| phosphorylation ABL1;PKM;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0032869| cellular response to insulin stimulus SRC;PKM GO:0032868| response to insulin stimulus LYN;PKM GO:0010033| response to organic substance PKM;CDK2 6721:[DB06616 DB03959] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03959|N,O6-Disulfo-Glucosamine FGF2;FGF1;HS3ST3A1;HGF;ANXA5 common genes common pathways GO:0000165| MAPKKK cascade HGF;MAP2K1;MAP2K2;FGF1;CAMK2G;FGF2 GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;FGF2;HGF;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HGF;ABL1;SRC;LYN GO:0050728| negative regulation of inflammatory response HGF;BCR GO:0000278| mitotic cell cycle HGF;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;HGF GO:0001934| positive regulation of protein phosphorylation ABL1;FGF1;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;FGF2;CDK2;MAP2K1;SRC;MAP2K2 GO:0032148| activation of protein kinase B activity SRC;FGF1 GO:0007399| nervous system development FGF2;CAMK2G GO:0043066| negative regulation of apoptotic process ANXA5;HGF;SRC;HCK GO:0002576| platelet degranulation ANXA5;LYN;HGF GO:0006935| chemotaxis FGF2;MAP2K1 GO:0008284| positive regulation of cell proliferation FGF2;FGF1;CDK2;LYN;HCK;HGF GO:0007275| multicellular organismal development FGF1;CAMK2G;CDK2;FGF2 GO:0018108| peptidyl-tyrosine phosphorylation FGF2;LYN;FGF1;MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;HGF GO:0007265| Ras protein signal transduction FGF2;CDK2 GO:2000573| positive regulation of DNA biosynthetic process HGF;SRC GO:0010033| response to organic substance ANXA5;CDK2 GO:0043406| positive regulation of MAP kinase activity SRC;FGF1;FGF2 GO:0000187| activation of MAPK activity FGF1;MAP3K2;FGF2;HGF;MAP2K1;MAP2K2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1;FGF2 GO:0008283| cell proliferation SRC;HGF;FGF1 GO:0007596| blood coagulation LYN;ANXA5 GO:1902533| FGF1;SRC GO:0007165| signal transduction MAP2K1;BCR;SRC;FGF2;LYN;ANXA5;FGF1 GO:0030154| cell differentiation HCK;CAMK2G;FGF1;FGF2 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;FGF2;SRC GO:0030335| positive regulation of cell migration HGF;LYN;FGF1 GO:0034605| cellular response to heat LYN;FGF1 GO:0010595| positive regulation of endothelial cell migration FGF1;ABL1 GO:0072089| stem cell proliferation ABCB1;FGF2 6722:[DB06616 DB01608] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation SRC;ADRA1B;AR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0010628| positive regulation of gene expression DRD1;AR;MAP2K1;SRC GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0006810| transport ABCB1;AR GO:0030168| platelet activation ADRA2A;SRC;LYN GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ABL1 GO:0030335| positive regulation of cell migration DRD1;ADRA2A;LYN GO:1903351| DRD1;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;ADRA2A;AR;ADRA1B;DRD1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;AR;MAP3K2;CDK2 GO:0042493| response to drug DRD1;SRC;ABCB1;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0030036| actin cytoskeleton organization ABL1;ADRA2A;BCR GO:0007275| multicellular organismal development ADRA1B;CAMK2G;CDK2 GO:0051259| protein oligomerization CAMK2G;AR GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0001932| regulation of protein phosphorylation MAP2K1;DRD1;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;CDK2 GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0032148| activation of protein kinase B activity SRC;ADRA2A GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;BCR;ADRA1B GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation ADRA2A;AR;HCK;CDK2;LYN 6723:[DB06616 DB06982] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06982|(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid SKP1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle SKP1;ABCB1;CDK2 GO:0038095| SKP1;LYN GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC;SKP1 6724:[DB06616 DB04224] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes common pathways GO:0043066| negative regulation of apoptotic process FABP1;PPARD;ALB;SRC;HCK GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0008284| positive regulation of cell proliferation CDK2;LYN;PPARD;HCK GO:0071222| cellular response to lipopolysaccharide PPARD;ABL1;BCR;SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0002576| platelet degranulation LYN;ALB GO:0050727| regulation of inflammatory response HCK;FABP4;LYN GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process PPARD;PPARG;PPARA;CYP3A4 GO:0007399| nervous system development FABP7;CAMK2G GO:0007507| heart development MAP2K1;PPARG;PPARA;RXRA;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PPARA;CDK2;RXRA;PPARD GO:0045087| innate immune response HCK;SRC;ABL1;LYN;PPARG GO:0042127| regulation of cell proliferation PPARD;SRC;ABL1 GO:0016032| viral reproduction RXRA;LYN;SRC;HCK GO:0050728| negative regulation of inflammatory response PPARA;PPARD;BCR GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;PPARD;RXRA;CDK2;PPARA;PPARG;MAP2K1;SRC;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARD;PPARG;PPARA;RXRA GO:0042493| response to drug SRC;ABCB1;FABP3;PPARG;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process FABP1;SRC GO:0070542| response to fatty acid SRC;FABP3 GO:0007165| signal transduction LYN;PPARG;MAP2K1;BCR;SRC GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0071456| cellular response to hypoxia SRC;PPARD;FABP1 GO:0030154| cell differentiation HCK;CAMK2G;PPARD GO:0010628| positive regulation of gene expression PPARD;SRC;MAP2K1 GO:0042359| vitamin D metabolic process GC;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;FABP4;PPARD;PPARG GO:0010033| response to organic substance PPARD;CDK2;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;FABP3;LYN;PPARG;FABP7 GO:0070301| cellular response to hydrogen peroxide FABP1;ABL1 GO:0014070| response to organic cyclic compound PPARG;LYN GO:0008283| cell proliferation PPARD;SRC GO:0006915| apoptotic process ABL1;PPARD GO:0032868| response to insulin stimulus FABP3;LYN;PPARA 6725:[DB06616 DB06719] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0007275| multicellular organismal development GNRHR;CDK2;CAMK2G GO:0060065| uterus development SRC;CYP19A1 GO:0001545| primary ovarian follicle growth LHCGR;SRC GO:0007165| signal transduction LYN;LHCGR;GNRHR;MAP2K1;BCR;SRC 6726:[DB06616 DB14487] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0051056| regulation of small GTPase mediated signal transduction A2M;BCR GO:0007165| signal transduction IGFALS;JUP;MAP2K1;FGA;BCR;SRC;LYN;C3;ESR1;PDIA3;BDKRB1 GO:0007420| brain development BCR;MT3 GO:0003014| renal system process AGT;BCR GO:0070555| response to interleukin-1 HDAC4;SRC GO:0065009| regulation of molecular function CAMK2G;AGT;IL3 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol BDKRB1;F2;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade FN1;LYN GO:0070542| response to fatty acid SRC;PON1 GO:0007050| cell cycle arrest MAP2K1;TP73;ABL1;TP53 GO:0030900| forebrain development SRC;APP GO:1900182| INS;SRC;F2;PARP1 GO:0031648| protein destabilization SRC;MDM2;GSN GO:0006977| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest CDK2;MDM2;TP53 GO:0032463| negative regulation of protein homooligomerization CLU;SRC GO:0048538| thymus development SOD1;MAP2K1;ABL1 GO:0060333| interferon-gamma-mediated signaling pathway MT2A;HCK;CAMK2G GO:0032489| regulation of Cdc42 protein signal transduction APOA1;ABL1;APOE GO:0002376| immune system process IGHM;C1QC;C3;CFI;LYN;IGHA1;C1S;C5;C4BPB;C8A;C1QB;C8B;S100A9;C1R;IGLV3-21;CLU;S100A8;C4BPA;CFB;PGLYRP2;IGKV1-17;HCK;FGA;C4B;SRC;FCN3;C8G;CFH GO:0050715| positive regulation of cytokine secretion SRC;INS GO:1900026| ABL1;APOA1;FGA GO:0006979| response to oxidative stress SOD1;TP53;APP;APOE;KRT1;MT3;ABL1;PRDX1 GO:0032869| cellular response to insulin stimulus PARP1;SRC GO:0007229| integrin-mediated signaling pathway APOA1;ABL1;HCK;SRC GO:0007204| elevation of cytosolic calcium ion concentration ESR1;APP;BDKRB1;ABL1;AGT;KNG1 GO:0071456| cellular response to hypoxia P4HB;MDM2;TP53;SRC;MT3 GO:0030154| cell differentiation CAMK2G;TP53;KRT6A;NME1;HCK GO:0006468| protein phosphorylation MAP3K2;APP;CAMK2G;CDK2;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0030168| platelet activation LYN;F2;FGA;SRC GO:0006810| transport ABCB1;TTR GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;NME1;ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1;PDCD6;AGT GO:0034605| cellular response to heat PDCD6;TP53;LYN GO:0008202| steroid metabolic process APOBR;APOA1;CYP2C8;APOE;APOL1;CYP3A4 GO:0030335| positive regulation of cell migration MMP9;LYN;INS GO:0043547| positive regulation of GTPase activity A2M;BCR GO:0072358| cardiovascular system development APOE;ABL1 GO:0098609| JUP;SRC;DSP GO:0070301| cellular response to hydrogen peroxide ABL1;MDM2 GO:0043407| negative regulation of MAP kinase activity LYN;APOE GO:0071375| cellular response to peptide hormone stimulus MDM2;SRC GO:0048013| ephrin receptor signaling pathway SRC;MMP9;LYN GO:0014911| positive regulation of smooth muscle cell migration SRC;VTN;HDAC4 GO:0050766| positive regulation of phagocytosis C3;AHSG;BCR GO:0045892| negative regulation of transcription, DNA-dependent HDAC1;HDAC4;TP53;MDM2;MT3;SRC;ENO1 GO:0006464| protein modification process ABL1;CPE GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;JUP GO:0007049| cell cycle TP73;SRC;TP53;BRCC3;CDK2 GO:0010033| response to organic substance CDK2;SOD1 GO:0008285| negative regulation of cell proliferation TP53;APP;HDAC4;LYN;HDAC1;TP73;MAP2K1;NME1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:1900272| APP;APOE;ABL1 GO:0030336| negative regulation of cell migration BCR;KRT16 GO:0050853| B cell receptor signaling pathway IGHA1;LYN;IGHM;ABL1 GO:0034614| cellular response to reactive oxygen species MMP9;TP53;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;MT3;INS;MDM2;APP;TP53;GSN;CLU;FN1 GO:0055085| transmembrane transport ABCB1;APOA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade S100A7;APP;ABL1;MT3;SRC;MAP2K2;FGA;MAP2K1 GO:0045184| establishment of protein localization MDM2;ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC;APOA1 GO:0000187| activation of MAPK activity SOD1;C5;MAP3K2;APP;MAP2K1;TP73;MAP2K2 GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;MAP2K2;PRDX1 GO:0006915| apoptotic process PDCD6;TP73;MT3;SIVA1;ABL1;TP53;APP;PARP1;S100A9;GSN;CLU;S100A8;APLP1 GO:0007596| blood coagulation SERPIND1;FGA;KNG1;F2;SERPINA1;F13B;F12;C4BPB;HDAC1;LYN;KLKB1;HBB GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TP73 GO:0030216| keratinocyte differentiation DSP;MAP2K1;S100A7;KRT16;KRT10 GO:0008283| cell proliferation KRT16;TP53;MT3;PRDX1;SRC GO:2000352| negative regulation of endothelial cell apoptosis FGA;ABL1 GO:0038095| IGKV1-17;IGLV3-21;LYN GO:0031175| neuron projection development APP;LYN GO:2000378| negative regulation of reactive oxygen species metabolic process BCR;MT3 GO:0050663| cytokine secretion LYN;AGT GO:0009636| response to toxin MDM2;MGMT;PON1;LYN GO:0014070| response to organic cyclic compound MGMT;LYN;TP53 GO:0016477| cell migration BDKRB1;SRC;JUP GO:0043200| response to amino acid stimulus TP53;LYN GO:0051496| positive regulation of stress fiber assembly APOA1;ABL1 GO:0042981| regulation of apoptotic process MAP2K2;TP73;MAP2K1;AGT;NME1;TP53;MAP3K2;ESR1 GO:0007399| nervous system development APP;HDAC4;CAMK2G;APLP1;IL3;NME1 GO:0045597| positive regulation of cell differentiation INS;MAP2K1 GO:0008360| regulation of cell shape HCK;F2;FN1;ALDOA GO:0032148| activation of protein kinase B activity INS;MT3;SRC GO:0007507| heart development MAP2K1;MDM2 GO:0045087| innate immune response CFH;C8G;SRC;FCN3;C4B;FGA;HCK;ABL1;PGLYRP2;CFB;C4BPA;JCHAIN;S100A8;CLU;APOL1;F12;C1R;APP;C8B;S100A9;C8A;C1QB;APCS;C4BPB;C5;C1S;KRT16;IGHA1;LYN;S100A7;CFI;C3;C1QC;IGHM GO:0071801| regulation of podosome assembly GSN;SRC;HCK GO:0007155| cell adhesion VTN;APP;FN1;APLP1;SRC;HCK;JUP;ABL1;IGFALS GO:0000122| negative regulation of transcription from RNA polymerase II promoter ENO1;TP73;HDAC8;MDM2;TP53;APP;PARP1;CDK2;HDAC1;HDAC4;ESR1 GO:0071260| cellular response to mechanical stimulus HDAC4;MAP3K2;AGT GO:0006974| response to DNA damage stimulus BRCC3;PARP1;TP53;MGMT;LYN;CDK2;TP73;ABL1;MPG GO:0051974| negative regulation of telomerase activity TP53;SRC GO:0006281| DNA repair MGMT;CDK2;BRCC3;PARP1;ABL1;MPG GO:0006629| lipid metabolic process APOBR;APOA1;APOE;APOL1;CLU;CYP3A4;PON1;C3 GO:0071732| cellular response to nitric oxide MT3;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0008284| positive regulation of cell proliferation CDK2;HDAC1;LYN;HDAC4;FN1;MDM2;KRT6A;INS;AGT;F2;HCK;IL3 GO:0006935| chemotaxis SERPIND1;MAP2K1;C5;S100A8;S100A9 GO:0042542| response to hydrogen peroxide SRC;HBA1;HBB;SOD1 GO:0009615| response to virus ENO1;SRC;CLU GO:0043065| positive regulation of apoptotic process MMP9;SOD1;APP;TP53;CLU;ABL1;KNG1;SRC;TP73 GO:0002576| platelet degranulation ORM2;CLU;ALDOA;SERPINA4;APP;TF;FN1;ITIH4;LYN;SOD1;APLP2;A1BG;SERPINA3;FGA;KNG1;ITIH3;SERPINA1;APOA1;A2M;AHSG GO:1901796| TP53;MDM2;HDAC1;CDK2;TP73 GO:0050727| regulation of inflammatory response PGLYRP2;AHSG;HCK;ESR1;LYN;S100A8;S100A9 GO:0042327| positive regulation of phosphorylation APP;LYN GO:0043066| negative regulation of apoptotic process MDM2;TP53;MMP9;SOD1;HDAC1;MGMT;HCK;SRC;MT3 GO:0009612| response to mechanical stimulus SRC;BDKRB1;PSPH GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0030155| regulation of cell adhesion ABL1;GSN GO:0060065| uterus development ESR1;SRC GO:0006897| endocytosis NME1;ABL1;APP;APLP1 GO:0030514| negative regulation of BMP signaling pathway DAND5;ABL1 GO:0031571| mitotic cell cycle G1/S transition DNA damage checkpoint TP53;CDK2;TP73 GO:0071398| cellular response to fatty acid NME1;SRC GO:0007265| Ras protein signal transduction CDK2;TP53 GO:0043393| regulation of protein binding APP;HDAC4;SRC GO:0034599| cellular response to oxidative stress PRDX1;CCS;MT3;ABL1;PARP1;P4HB;SOD1;HDAC1;MGMT GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL3;LYN;HDAC1 GO:0048678| response to axon injury SOD1;LYN GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;IL3;LYN GO:0043542| endothelial cell migration ABL1;S100A2 GO:0007275| multicellular organismal development TPI1;TP53;CAMK2G;CDK2;HRNR;F2 GO:0032496| response to lipopolysaccharide S100A8;BDKRB1;HDAC1;S100A7;BCR GO:0045931| positive regulation of mitotic cell cycle ABL1;APP;MDM2 GO:0042127| regulation of cell proliferation ABL1;SRC;JUP;AGT GO:0001932| regulation of protein phosphorylation FN1;LYN;MAP2K1;APOA1 GO:0030516| regulation of axon extension APOE;ABL1 GO:0001933| negative regulation of protein phosphorylation LYN;BDKRB1 GO:0051353| positive regulation of oxidoreductase activity ABL1;CCS GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0031954| positive regulation of protein autophosphorylation INS;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;INS;IL3;SRC;AGT;LYN;VTN;APP;TP53 GO:0019221| cytokine-mediated signaling pathway IL3;HCK GO:0051924| regulation of calcium ion transport AGT;CAMK2G GO:0034446| substrate adhesion-dependent cell spreading FN1;ABL1;SRC GO:0038096| IGLV3-21;LYN;HCK;SRC;IGKV1-17;ABL1 GO:1902036| ABL1;TP73 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MMP9;SRC GO:0002250| adaptive immune response IGHM;LYN;IGHA1;IGLV3-21;JCHAIN;IGKV1-17;FGA GO:0046628| positive regulation of insulin receptor signaling pathway INS;SRC GO:0051897| positive regulation of protein kinase B signaling cascade APP;SRC;INS GO:0000165| MAPKKK cascade CAMK2G;INS;MAP2K1;MAP2K2;IL3 GO:0006954| inflammatory response BDKRB1;S100A8;S100A9;HDAC4;C5;KRT16;KLKB1;LYN;C3;SERPINA3;C4B;HCK;KNG1 GO:0050728| negative regulation of inflammatory response KRT1;APOA1;BCR;APOE GO:0006298| mismatch repair TP73;ABL1 GO:0010976| positive regulation of neuron projection development NME1;AGT;LYN;APOE GO:0070371| ERK1 and ERK2 cascade MAP2K1;AGT;MAP2K2;APOA1;MT3 GO:0051301| cell division BRCC3;CDK2 GO:0016032| viral reproduction LYN;HDAC1;IDE;MDM2;TP53;APOA2;SIVA1;HCK;CFH;TP73;SRC GO:0002762| negative regulation of myeloid leukocyte differentiation NME1;LYN GO:0050900| leukocyte migration LYN;IGHM;MMP9;FN1;IGHA1;IGLV3-21;JCHAIN;IGKV1-17;F2;SRC GO:0050885| neuromuscular process controlling balance ABL1;BCR;APP GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006914| autophagy TP53;S100A9;S100A8;ABL1 GO:0055114| oxidation-reduction process PRDX1;CCS;CP;CYP2C8;ADH1C;P4HB;PDIA3;CYP3A4;GAPDHS;SOD1 GO:0034332| adherens junction organization JUP;SRC;DSP GO:0001934| positive regulation of protein phosphorylation F2;ABL1;MT3;APP;C3;LYN;MMP9 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;MT3;SRC GO:0006355| regulation of transcription, DNA-dependent TP53;PARP1;HDAC1;EEF1A1;HDAC4;ESR1;TP73;ENO1;HDAC8;INS;ABL1 GO:0014003| oligodendrocyte development LYN;GSN GO:0042493| response to drug SOD1;HDAC1;LYN;HDAC4;MGMT;TP53;MDM2;APOA2;APOA1;NME1;ABCB1;TP73;SRC GO:0010629| negative regulation of gene expression NME1;HDAC8;MAP2K1;AGT;MAP2K2;HDAC1;ESR1;MDM2;APP GO:0007346| regulation of mitotic cell cycle TP73;MAP2K2;MAP2K1;MAP3K2 GO:0031667| response to nutrient levels SOD1;PON1;PSPH;SRC GO:0045893| positive regulation of transcription, DNA-dependent MT3;SRC;TP73;MAP2K2;AGT;MAP2K1;ESR1;HDAC4;HDAC1;CDK2;MAP3K2;TP53 GO:1901216| CLU;APOE;APP;PARP1;ABL1 6727:[DB06616 DB05490] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05490|T131 PPARG common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction PPARG;LYN;SRC;BCR;MAP2K1 GO:0014070| response to organic cyclic compound LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0010033| response to organic substance CDK2;PPARG GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response PPARG;LYN;SRC;HCK;ABL1 GO:0007507| heart development PPARG;MAP2K1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug LYN;PPARG;ABCB1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;MAP3K2;PPARG;CDK2 6728:[DB06616 DB04552] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0042127| regulation of cell proliferation ABL1;SRC;PTGS1;PLA2G4A;PTGS2 GO:0032496| response to lipopolysaccharide BCR;PTGS2 GO:0006629| lipid metabolic process PLA2G1B;PTGS1;SLC16A1;PTGS2;PLA2G4A;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0035556| intracellular signal transduction LYN;CAMK2G;SRC;PLA2G1B;BCR GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;UGT1A9;CYP3A4 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0008284| positive regulation of cell proliferation HCK;PTGS2;LYN;CDK2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2C8;PTGS2;CYP3A4 GO:0050900| leukocyte migration LYN;SRC;SLC16A1 GO:0042493| response to drug PTGS2;LYN;ABCB1;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response HCK;PTGS1;PTGS2;LYN GO:0006810| transport CLCNKA;ABCB1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B GO:0034605| cellular response to heat PTGS2;LYN GO:0070542| response to fatty acid PTGS2;SRC GO:0017144| drug metabolic process CYP3A4;UGT1A9;CYP2C8 GO:0007165| signal transduction SRC;PLA2G1B;BCR;MAP2K1;LYN GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0000187| activation of MAPK activity MAP2K2;PLA2G1B;MAP2K1;MAP3K2 GO:0055085| transmembrane transport CLCNKA;SLC16A7;SLC16A1;ABCB1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 6729:[DB06616 DB11217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11217|Arbutin TYR;ALB common genes common pathways GO:0008283| cell proliferation SRC;TYR GO:0048538| thymus development ABL1;TYR;MAP2K1 GO:0055114| oxidation-reduction process CYP2C8;TYR;CYP3A4 GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation LYN;ALB 6730:[DB06616 DB03541] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0009636| response to toxin LYN;TYMS GO:0014070| response to organic cyclic compound LYN;TYMS GO:0055114| oxidation-reduction process CYP2C8;DHRS4L1;NQO2;CYP3A4 GO:0042493| response to drug ABCB1;SRC;LYN;TYMS GO:0006805| xenobiotic metabolic process CYP2C8;NQO2;CYP3A4 6731:[DB06616 DB00138] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00138|Cystine SLC7A11;CTNS;SLC7A9;SLC3A1;SLC16A10 common genes common pathways GO:0009636| response to toxin LYN;SLC7A11 GO:0055085| transmembrane transport ABCB1;CTNS;SLC16A10 GO:0006979| response to oxidative stress SLC7A11;ABL1 GO:0007420| brain development BCR;SLC7A11;CTNS GO:0050900| leukocyte migration SLC7A11;SLC7A9;LYN;SRC 6732:[DB06616 DB05992] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05992|Plinabulin TNF common genes common pathways GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;TNF GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;TNF GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TNF;MAP3K2 GO:0010628| positive regulation of gene expression TNF;MAP2K1;SRC GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0010033| response to organic substance CDK2;TNF GO:0050766| positive regulation of phagocytosis BCR;TNF GO:0045892| negative regulation of transcription, DNA-dependent SRC;TNF GO:0045930| negative regulation of mitotic cell cycle TNF;ABL1 GO:0050715| positive regulation of cytokine secretion TNF;SRC GO:0051222| positive regulation of protein transport TNF;SRC GO:0010629| negative regulation of gene expression TNF;MAP2K1;MAP2K2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;TNF;MAP2K2;SRC;MAP2K1 GO:0050900| leukocyte migration LYN;TNF;SRC GO:0001934| positive regulation of protein phosphorylation TNF;LYN;ABL1 GO:0006954| inflammatory response LYN;TNF;HCK GO:0000165| MAPKKK cascade CAMK2G;TNF;MAP2K2;MAP2K1 GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNF GO:0042127| regulation of cell proliferation TNF;SRC;ABL1 GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;ABL1 GO:0007275| multicellular organismal development CAMK2G;TNF;CDK2 GO:0043065| positive regulation of apoptotic process TNF;SRC;ABL1 GO:0050727| regulation of inflammatory response HCK;LYN;TNF GO:0071222| cellular response to lipopolysaccharide TNF;SRC;BCR;ABL1 GO:0009615| response to virus TNF;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;LYN;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 6733:[DB06616 DB01010] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01010|Edrophonium ACHE;BCHE common genes common pathways GO:0008283| cell proliferation SRC;ACHE GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0007399| nervous system development CAMK2G;ACHE GO:0007155| cell adhesion HCK;SRC;ABL1;ACHE GO:0042493| response to drug LYN;BCHE;ABCB1;SRC GO:0006260| DNA replication ACHE;CDK2 6734:[DB06616 DB01063] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01063|Acetophenazine DRD2;DRD1;AR common genes common pathways GO:0042493| response to drug LYN;DRD1;DRD2;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0048678| response to axon injury DRD2;LYN GO:0051259| protein oligomerization CAMK2G;AR GO:0001932| regulation of protein phosphorylation DRD1;MAP2K1;LYN GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;AR GO:0035556| intracellular signal transduction DRD2;SRC;BCR;LYN;CAMK2G GO:0042327| positive regulation of phosphorylation LYN;AR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;DRD2;MAP2K2;MAP2K1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation SRC;AR GO:0009636| response to toxin LYN;DRD2 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;AR;LYN GO:0030336| negative regulation of cell migration DRD2;BCR GO:0010628| positive regulation of gene expression DRD1;AR;MAP2K1;SRC GO:0006810| transport ABCB1;AR GO:0030335| positive regulation of cell migration DRD1;LYN GO:0007165| signal transduction AR;DRD1;BCR;DRD2;SRC;MAP2K1;LYN GO:1903351| ABL1;DRD1 GO:0030900| forebrain development DRD2;SRC GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 6735:[DB06616 DB04310] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;PDF;LYN;CDK2 6736:[DB06616 DB08479] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0014070| response to organic cyclic compound LYN;TYMS GO:0009636| response to toxin TYMS;LYN GO:0042493| response to drug LYN;TYMS;SRC;ABCB1 6737:[DB06616 DB01695] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01695|N-Hydroxy-4-Phosphono-Butanamide TPI1 common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;TPI1 6738:[DB06616 DB01525] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01525|Ecgonine BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0042493| response to drug ABCB1;SRC;LYN;BCHE 6739:[DB06616 DB01035] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DNMT1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007265| Ras protein signal transduction CDK2;DNMT1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0042127| regulation of cell proliferation SRC;DNMT1;ABL1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0023014| signal transduction via phosphorylation event KCNH2;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent DNMT1;ABL1 GO:0042493| response to drug SRC;ABCB1;BCHE;LYN GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0006813| potassium ion transport CDK2;KCNH2 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0045892| negative regulation of transcription, DNA-dependent SRC;DNMT1 GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;DNMT1 GO:0055085| transmembrane transport SLC47A1;ABCB1;SLC22A2;SCN5A;SLC47A2;SLC22A1;SLC22A4;SLC22A3;KCNH2;SLC22A5 GO:0006855| drug transmembrane transport SLC22A1;SLC22A3;SLC22A5;ABCB1;SLC47A1;SLC22A2;SLC47A2 6740:[DB06616 DB11591] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;HRH1;LYN GO:0030154| cell differentiation HCK;ABCB5;CAMK2G GO:0042908| xenobiotic transport ABCB5;ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO2B1;ABCB5;SLCO1A2 GO:0006855| drug transmembrane transport ABCB5;ABCB1 GO:0006954| inflammatory response HRH1;LYN;HCK GO:0043114| regulation of vascular permeability HRH1;SRC;BCR 6741:[DB06616 DB01810] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01810|[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways 6742:[DB06616 DB05352] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05352|Fx-1006A TTR common genes common pathways GO:0006810| transport TTR;ABCB1 6743:[DB06616 DB06775] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06775|Carglumic acid CPS1 common genes common pathways GO:0032496| response to lipopolysaccharide CPS1;BCR GO:0042493| response to drug ABCB1;SRC;LYN;CPS1 GO:0009636| response to toxin CPS1;LYN GO:0043200| response to amino acid stimulus LYN;CPS1 6744:[DB06616 DB05969] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK7;CDK2 GO:0045785| positive regulation of cell adhesion VEGFA;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;VEGFA GO:0008283| cell proliferation SRC;CDK7 GO:0043406| positive regulation of MAP kinase activity SRC;VEGFA GO:0007049| cell cycle CDK7;CDK2;SRC GO:0010628| positive regulation of gene expression VEGFA;SRC;MAP2K1 GO:0030154| cell differentiation HCK;VEGFA;CAMK2G GO:0006468| protein phosphorylation CDK7;CAMK2G;CDK2;LYN;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0071456| cellular response to hypoxia VEGFA;SRC GO:0010595| positive regulation of endothelial cell migration VEGFA;ABL1 GO:0016310| phosphorylation LYN;CDK2;CDK7;CAMK2G;MAP3K2;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2 GO:0030335| positive regulation of cell migration LYN;VEGFA GO:0007050| cell cycle arrest ABL1;MAP2K1;CDK7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;VEGFA GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;ABL1 GO:0010629| negative regulation of gene expression VEGFA;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent CDK7;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;CDK7;MAP3K2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;LYN;SRC;ABL1 GO:0031954| positive regulation of protein autophosphorylation VEGFA;SRC GO:0000082| G1/S transition of mitotic cell cycle CDK2;CAMK2G;CDK7 GO:0051301| cell division CDK2;CDK7 GO:0007275| multicellular organismal development VEGFA;CAMK2G;CDK2 GO:0007498| mesoderm development VEGFA;HCK GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein VEGFA;LYN GO:0051894| positive regulation of focal adhesion assembly VEGFA;ABL1 GO:0008360| regulation of cell shape VEGFA;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;CDK2 GO:0007399| nervous system development VEGFA;CAMK2G GO:0006281| DNA repair ABL1;CDK7;CDK2 GO:0006974| response to DNA damage stimulus CDK2;LYN;CDK7;ABL1 GO:0002576| platelet degranulation VEGFA;LYN GO:0008284| positive regulation of cell proliferation VEGFA;LYN;CDK2;HCK GO:0042327| positive regulation of phosphorylation VEGFA;LYN GO:0043066| negative regulation of apoptotic process SRC;HCK;VEGFA GO:0051272| positive regulation of cellular component movement VEGFA;LYN GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;VEGFA 6745:[DB06616 DB00809] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM3;LYN;CHRM2;CHRM1;MAP2K1;CHRM4;BCR;SRC GO:0008283| cell proliferation CHRM4;SRC;CHRM3;CHRM1 GO:0006464| protein modification process CHRM1;CHRM3;ABL1 GO:0009615| response to virus CHRM2;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;CHRM1;HCK GO:0007399| nervous system development CHRM3;CHRM2;CHRM1;CAMK2G 6746:[DB06616 DB02047] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1 GO:0006954| inflammatory response LYN;HCK;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C8 GO:0006979| response to oxidative stress PTGS1;ABL1 6747:[DB06616 DB04879] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways GO:0016032| viral reproduction LYN;KDR;HCK;SRC GO:0070371| ERK1 and ERK2 cascade MAP2K2;KDR;MAP2K1 GO:0001934| positive regulation of protein phosphorylation ABL1;KDR;LYN;FLT4 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;KDR GO:0038083| LYN;ABL1;KDR;HCK;SRC GO:0008360| regulation of cell shape HCK;KDR GO:0043066| negative regulation of apoptotic process SRC;KDR;HCK;FLT4 GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC;FLT4;FLT1 GO:0006935| chemotaxis FLT1;MAP2K1 GO:0008284| positive regulation of cell proliferation KDR;HCK;FLT1;LYN;CDK2;FLT4 GO:0018108| peptidyl-tyrosine phosphorylation KDR;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;FLT1;LYN;FLT4 GO:0007275| multicellular organismal development FLT1;CAMK2G;CDK2;KDR GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0043406| positive regulation of MAP kinase activity FLT1;SRC GO:0046777| protein autophosphorylation LYN;FLT4;CAMK2G;FLT1;ABL1;KDR;HCK;BCR;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;KDR;ABL1;FLT4 GO:0016477| cell migration SRC;FLT1 GO:2000352| negative regulation of endothelial cell apoptosis KDR;ABL1 GO:0030154| cell differentiation CAMK2G;FLT1;HCK;KDR GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;HCK;KDR;MAP2K1;ABL1;FLT1;MAP3K2;CAMK2G;FLT4;CDK2;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;KDR;FLT1;FLT4;LYN GO:0030335| positive regulation of cell migration FLT1;LYN;KDR GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;FLT1;SRC GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;KDR;ABL1;FLT1;MAP3K2;CAMK2G;FLT4;CDK2;LYN GO:0010595| positive regulation of endothelial cell migration FLT4;ABL1;KDR 6748:[DB06616 DB02303] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DPYD;CYP2C8 6749:[DB06616 DB00004] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0008283| cell proliferation IL2RA;SRC GO:0006915| apoptotic process IL2RA;ABL1 GO:0002376| immune system process HCK;SRC;IL2RA;LYN GO:0065009| regulation of molecular function IL2RA;IL2RB;IL2RG;CAMK2G GO:0007165| signal transduction IL2RG;IL2RB;LYN;MAP2K1;BCR;SRC GO:0016032| viral reproduction HCK;SRC;IL2RB;IL2RG;LYN GO:0006954| inflammatory response HCK;IL2RA;LYN GO:0050728| negative regulation of inflammatory response BCR;IL2RA GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;IL2RB;IL2RG;IL2RA;CAMK2G GO:0019221| cytokine-mediated signaling pathway IL2RB;HCK GO:0043066| negative regulation of apoptotic process SRC;HCK;IL2RB GO:0050777| negative regulation of immune response LYN;IL2RA 6750:[DB06616 DB05461] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0016310| phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;SRC;HTR2B;ABL1 GO:0030168| platelet activation ADRA2C;ADRA2B;LYN;SRC GO:0050715| positive regulation of cytokine secretion SRC;HTR2B GO:0007165| signal transduction MAP2K1;SRC;BCR;HTR2B;LYN;ADRA2B;ADRA2C GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;ADRA2B GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1;HTR2B GO:0043406| positive regulation of MAP kinase activity HTR2B;SRC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;HTR2B GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2B;HCK GO:0007507| heart development MAP2K1;HTR2B GO:0032148| activation of protein kinase B activity SRC;ADRA2C;ADRA2B GO:0042493| response to drug LYN;HTR2B;ABCB1;SRC GO:0070371| ERK1 and ERK2 cascade MAP2K2;MAP2K1;HTR2B 6751:[DB06616 DB04849] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04849|Cediranib KDR common genes common pathways GO:0051894| positive regulation of focal adhesion assembly ABL1;KDR GO:0007275| multicellular organismal development KDR;CAMK2G;CDK2 GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;HCK;MAP2K1;KDR;SRC;MAP2K2;BCR GO:0043066| negative regulation of apoptotic process SRC;HCK;KDR GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;KDR;HCK GO:0008360| regulation of cell shape HCK;KDR GO:0010629| negative regulation of gene expression KDR;MAP2K1;MAP2K2 GO:0038083| SRC;HCK;KDR;ABL1;LYN GO:0001934| positive regulation of protein phosphorylation LYN;KDR;ABL1 GO:0016032| viral reproduction HCK;KDR;SRC;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K2;KDR;MAP2K1 GO:0030335| positive regulation of cell migration LYN;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway KDR;HCK;LYN GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;KDR;HCK GO:0030154| cell differentiation HCK;KDR;CAMK2G GO:0006468| protein phosphorylation MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;KDR;HCK;MAP2K2;BCR;SRC;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;KDR;MAP2K1;SRC;MAP2K2 GO:0046777| protein autophosphorylation BCR;SRC;KDR;HCK;ABL1;CAMK2G;LYN 6752:[DB06616 DB02690] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02690|NU1025 PARP1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:1901216| ABL1;PARP1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PARP1 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;PARP1 GO:0006281| DNA repair ABL1;CDK2;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:0006915| apoptotic process ABL1;PARP1 GO:0032869| cellular response to insulin stimulus PARP1;SRC GO:1900182| SRC;PARP1 6753:[DB06616 DB02901] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes ABCB1 common pathways GO:0008284| positive regulation of cell proliferation LYN;CDK2;AR;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0060065| uterus development ESR1;CYP19A1;SRC GO:0042327| positive regulation of phosphorylation LYN;AR GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;ESR1;MAP3K2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1;AR GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0006629| lipid metabolic process HSD17B1;CYP3A4;CYP11A1 GO:1901529| ABCB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0051259| protein oligomerization CAMK2G;AR GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C2;AR;ABL1 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0042493| response to drug LYN;SRC;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;AR;SRC;MAP2K2;MAP2K1 GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP17A1;CYP2C8;HSD17B1;CYP3A4;CYP19A1;CYP11A1 GO:2001225| regulation of chloride transport ABCB1 GO:0007165| signal transduction MAP2K1;BCR;SRC;NR3C2;AR;LYN;ESR1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP17A1;CYP2C8;CYP3A4;CYP11A1 GO:0045332| phospholipid translocation ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0006810| transport AR;ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0042359| vitamin D metabolic process CYP11A1;CYP3A4 GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0008285| negative regulation of cell proliferation LYN;AR;MAP2K1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation AR;SRC GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0006855| drug transmembrane transport ABCB1 6754:[DB06616 DB00163] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00163|Vitamin E NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;SEC14L4;SEC14L3;SEC14L2;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0006816| calcium ion transport PRKCB;CAMK2G GO:0051602| response to electrical stimulus NQO1;SRC GO:0090330| regulation of platelet aggregation PRKCA;LYN GO:0006954| inflammatory response LYN;HCK;ALOX5 GO:0002250| adaptive immune response LYN;PRKCB GO:0038128| PRKCA;SRC GO:0031667| response to nutrient levels SOD1;GSTP1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;NR1I2;CDK2;MAP2K1;SRC;MAP2K2;SEC14L2 GO:0042493| response to drug ABCB1;SRC;SOD1;LYN GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;NR1I2 GO:0006355| regulation of transcription, DNA-dependent ABL1;SEC14L2;PRKCB;PPP2CA;NR1I2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;GSTO1;HMOX1;NQO1;CYP2C8;ALOX5 GO:0035556| intracellular signal transduction LYN;HMOX1;CAMK2G;DGKA;PRKCA;PRKCB;SRC;BCR GO:0006805| xenobiotic metabolic process NQO1;CYP3A4;NR1I2;CYP2C8;GSTP1 GO:0043066| negative regulation of apoptotic process HCK;GSTP1;SRC;GCLC;SOD1;NQO1 GO:0030155| regulation of cell adhesion PPP2CA;ABL1 GO:0002576| platelet degranulation SOD1;LYN GO:0043065| positive regulation of apoptotic process SOD1;HMOX1;ABL1;SRC GO:1904528| PPP2CB;PPP2CA;ABL1 GO:0042542| response to hydrogen peroxide SRC;SOD1;PPP2CB;HMOX1 GO:0018105| peptidyl-serine phosphorylation CDK2;CAMK2G;PRKCA;SRC;PRKCB GO:0071222| cellular response to lipopolysaccharide GSTP1;BCR;SRC;ABL1 GO:0006629| lipid metabolic process TTPA;CYP3A4 GO:0071260| cellular response to mechanical stimulus GCLC;MAP3K2 GO:0007155| cell adhesion PRKCA;ABL1;SRC;HCK GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;GSTP1 GO:0045931| positive regulation of mitotic cell cycle ABL1;PRKCA GO:0007498| mesoderm development HCK;PPP2CA GO:0048678| response to axon injury SOD1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;PRKCB;ABL1 GO:0034599| cellular response to oxidative stress GSTP1;ABL1;SOD1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;NR1I2 GO:0050853| B cell receptor signaling pathway LYN;ABL1;PRKCB GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;PPP2CA;MAP2K1 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;HMOX1 GO:0010033| response to organic substance PPP2CA;SOD1;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent GCLC;SRC;NR1I2 GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1 GO:0007411| axon guidance PRKCA;SRC GO:0043200| response to amino acid stimulus LYN;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;ABL1;LYN GO:0006470| protein dephosphorylation PPP2CA;PPP2CB;CAMK2G GO:0014070| response to organic cyclic compound NQO1;LYN GO:0009636| response to toxin LYN;NQO1;TTPA;GSTP1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis HMOX1;ABL1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1;GCLC GO:0000187| activation of MAPK activity MAP3K2;SOD1;MAP2K2;MAP2K1 GO:0032872| regulation of stress-activated MAPK cascade MAP2K2;GSTP1;MAP2K1 GO:0006915| apoptotic process ABL1;PRKCA;PRKCB;PPP2CA;HMOX1 GO:0045785| positive regulation of cell adhesion SRC;PRKCA GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;PRKCA;ABL1 GO:0006979| response to oxidative stress SOD1;NQO1;HMOX1;GCLC;ABL1 GO:0050861| positive regulation of B cell receptor signaling pathway LYN;PRKCB GO:0002376| immune system process LYN;HCK;SRC;PRKCB GO:0048538| thymus development SOD1;ABL1;MAP2K1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;HMOX1 GO:0051321| meiotic cell cycle PPP2CA;CDK2 GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN GO:0070555| response to interleukin-1 PRKCA;GCLC;SRC GO:0007165| signal transduction NR1I2;LYN;BCR;SRC;PRKCB;MAP2K1 GO:0009725| response to hormone stimulus LYN;GCLC GO:0030335| positive regulation of cell migration LYN;PRKCA GO:0008202| steroid metabolic process CYP3A4;NR1I2;CYP2C8 GO:0034605| cellular response to heat LYN;HMOX1 GO:0007417| central nervous system development SRC;GSTP1;LYN GO:0010595| positive regulation of endothelial cell migration PRKCA;ABL1 GO:0016310| phosphorylation DGKA;MAP3K2;LYN;CDK2;CAMK2G;MAP2K1;HCK;MAP2K2;BCR;PRKCB;SRC;PRKCA;ABL1 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0030168| platelet activation PRKCA;PRKCB;SRC;LYN;DGKA GO:0006810| transport ABCB1;TTPA GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;PRKCB;MAP2K1;HCK;PRKCA;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0032869| cellular response to insulin stimulus GCLC;SRC;GSTP1 GO:0071456| cellular response to hypoxia HMOX1;SRC 6755:[DB06616 DB03910] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03910|S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN GO:0043542| endothelial cell migration ABL1;NOS3 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;NOS3;MAP2K1 6756:[DB06616 DB06202] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes common pathways GO:0007165| signal transduction CNR2;ESR1;LYN;SRC;BCR;MAP2K1;ESR2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC;ESR1 GO:0060065| uterus development SRC;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP2K2;MAP2K1;MAP3K2;ESR1 GO:0032496| response to lipopolysaccharide CNR2;BCR GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0050728| negative regulation of inflammatory response BCR;CNR2 GO:0006954| inflammatory response HCK;CNR2;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;ESR1;MAP2K1;MAP2K2;SRC;ESR2 GO:0008209| androgen metabolic process CYP3A4;ESR1 6757:[DB06616 DB08798] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08798|Sulfamoxole CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 6758:[DB06616 DB05905] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05905|TD-2749 HTR4 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;HTR4 6759:[DB06616 DB07477] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07477|Felbinac CTSL common genes common pathways GO:0002250| adaptive immune response LYN;CTSL 6760:[DB06616 DB00807] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00807|Proparacaine SCN10A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN10A 6761:[DB06616 DB07784] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07784|[4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID IGKC common genes common pathways GO:0050900| leukocyte migration IGKC;LYN;SRC GO:0002250| adaptive immune response LYN;IGKC GO:0038096| LYN;IGKC;ABL1;HCK;SRC GO:0045087| innate immune response ABL1;HCK;SRC;LYN;IGKC GO:0038095| LYN;IGKC GO:0050853| B cell receptor signaling pathway ABL1;LYN;IGKC GO:0002376| immune system process HCK;SRC;LYN;IGKC 6762:[DB06616 DB07121] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07121|4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0048536| spleen development ADAM17;ABL1 GO:0030335| positive regulation of cell migration LYN;ADAM17 GO:0042493| response to drug SRC;ABCB1;LYN;ADAM17 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;ADAM17 GO:0001934| positive regulation of protein phosphorylation ABL1;LYN;ADAM17 GO:0008284| positive regulation of cell proliferation ADAM17;CDK2;LYN;HCK GO:0051272| positive regulation of cellular component movement ADAM17;LYN GO:0007155| cell adhesion ADAM17;SRC;HCK;ABL1 GO:0032496| response to lipopolysaccharide BCR;ADAM17 GO:0048870| cell motility ADAM17;MAP2K1 6763:[DB06616 DB01972] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0007399| nervous system development DLG4;CAMK2G GO:0000165| MAPKKK cascade DLG4;CAMK2G;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent HINT1;ABL1 GO:0055114| oxidation-reduction process CYP2C8;GMPR;CYP3A4 GO:0050885| neuromuscular process controlling balance DLG4;ABL1;BCR GO:0007165| signal transduction SRC;BCR;MAP2K1;PDE5A;HINT1;DLG4;LYN GO:0016310| phosphorylation LYN;CDK2;CAMK2G;GUK1;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0007204| elevation of cytosolic calcium ion concentration ABL1;DLG4 GO:0006464| protein modification process TGM3;ABL1 GO:0043406| positive regulation of MAP kinase activity PDE5A;SRC GO:0030216| keratinocyte differentiation MAP2K1;TGM3 GO:0006915| apoptotic process ABL1;HINT1 GO:0045184| establishment of protein localization ABL1;DLG4 GO:0055085| transmembrane transport DLG4;ABCB1 6764:[DB06616 DB05662] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05662|NP-50301 ESR1 common genes common pathways GO:0007165| signal transduction BCR;SRC;MAP2K1;ESR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0060065| uterus development ESR1;SRC GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;SRC;MAP2K2;MAP3K2;CDK2;ESR1 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 6765:[DB06616 DB02621] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02621|Latrunculin A ACTA1;GSN common genes common pathways GO:0006915| apoptotic process ABL1;GSN GO:0010628| positive regulation of gene expression GSN;MAP2K1;ACTA1;SRC GO:0031648| protein destabilization SRC;GSN GO:0014003| oligodendrocyte development LYN;GSN GO:0009612| response to mechanical stimulus ACTA1;SRC GO:0030155| regulation of cell adhesion ABL1;GSN GO:0071801| regulation of podosome assembly GSN;SRC;HCK 6766:[DB06616 DB05511] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05511|Piclidenoson ADORA3 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;ADORA3;LYN GO:0030336| negative regulation of cell migration ADORA3;BCR GO:0007165| signal transduction SRC;BCR;MAP2K1;ADORA3;LYN GO:0006954| inflammatory response HCK;LYN;ADORA3 6767:[DB06616 DB06879] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;ABL1;SRC;BCR GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0032496| response to lipopolysaccharide NOS2;BCR 6768:[DB06616 DB07637] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07637|Dibromotyrosine EPOR common genes common pathways GO:0007420| brain development BCR;EPOR GO:0007165| signal transduction EPOR;LYN;BCR;SRC;MAP2K1 GO:0007507| heart development EPOR;MAP2K1 GO:0019221| cytokine-mediated signaling pathway EPOR;HCK 6769:[DB06616 DB03158] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways GO:0043547| positive regulation of GTPase activity BCR;INPP5B GO:0051056| regulation of small GTPase mediated signal transduction INPP5B;BCR GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;INPP5B 6770:[DB06616 DB05202] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways GO:0007596| blood coagulation VWF;LYN;GP1BA GO:0030168| platelet activation LYN;VWF;GP1BA;SRC GO:0019221| cytokine-mediated signaling pathway GP1BA;HCK GO:0007155| cell adhesion VWF;GP1BA;SRC;HCK;ABL1 GO:0002576| platelet degranulation LYN;VWF 6771:[DB06616 DB01622] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;ADRA1B GO:0048678| response to axon injury LYN;DRD2 GO:0001932| regulation of protein phosphorylation MAP2K1;DRD1;LYN GO:0035556| intracellular signal transduction SRC;DRD2;ADRA1A;BCR;ADRA1B;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB GO:0002576| platelet degranulation ALB;LYN GO:0008284| positive regulation of cell proliferation HTR1A;CDK2;LYN;HTR2A;HCK GO:0042493| response to drug HTR2A;LYN;DRD1;ABCB1;DRD2;SRC;ADRA1A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;SRC;LYN;HTR2A GO:0016032| viral reproduction LYN;HTR2A;SRC;HCK GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1B;ABL1;HTR2A GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0030900| forebrain development DRD2;SRC GO:1903351| DRD1;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0007165| signal transduction HTR1A;LYN;HTR2A;ADRA1B;DRD1;ADRA1A;SRC;DRD2;BCR;MAP2K1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0006915| apoptotic process ABL1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;DRD2;ADRA1A;MAP2K1;HTR2A GO:0009636| response to toxin DRD2;LYN GO:0008283| cell proliferation HTR1A;ADRA1B;SRC GO:0008285| negative regulation of cell proliferation MAP2K1;ADRA1A;DRD2;LYN GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0010628| positive regulation of gene expression DRD1;SRC;MAP2K1 GO:0030336| negative regulation of cell migration BCR;DRD2 6772:[DB06616 DB09286] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0042493| response to drug HTR2A;LYN;DRD3;HTR2B;DRD1;ABCB1;SRC;DRD2;ADRA1A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;HTR2A;ABL1;SRC GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0070371| ERK1 and ERK2 cascade HTR2B;MAP2K2;MAP2K1 GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;HTR2B GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0048678| response to axon injury LYN;DRD2 GO:0007275| multicellular organismal development CDK2;CAMK2G;ADRA1D;ADRA1B GO:0001932| regulation of protein phosphorylation LYN;MAP2K1;DRD1 GO:0032148| activation of protein kinase B activity ADRA2A;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;DRD3 GO:0007507| heart development HTR2B;MAP2K1 GO:0008284| positive regulation of cell proliferation DRD3;LYN;CDK2;HTR2A;ADRA1D;ADRA2A;HTR2B;HCK GO:0043066| negative regulation of apoptotic process HTR2B;HCK;SRC GO:0035556| intracellular signal transduction LYN;CAMK2G;DRD2;SRC;ADRA1A;BCR;ADRA1B GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;HTR2B;DRD2;SRC;ADRA1A;MAP2K2;MAP2K1;HTR2A GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;DRD4;MAP3K2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0008283| cell proliferation SRC;ADRA1B;ADRA1D GO:0009636| response to toxin LYN;DRD2 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2B;ADRA2A;HTR2A GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;ADRA1A;LYN GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0010628| positive regulation of gene expression SRC;MAP2K1;DRD1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ADRA1D;ADRA1B;ABL1;ADRA1A GO:0030168| platelet activation LYN;SRC;ADRA2A GO:0016310| phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;HTR2B;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0030335| positive regulation of cell migration ADRA2A;DRD1;LYN GO:0043547| positive regulation of GTPase activity HTR2B;BCR GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0007165| signal transduction DRD3;LYN;HTR2A;DRD4;ADRA1D;DRD1;ADRA2A;ADRA1B;HTR2B;MAP2K1;DRD2;SRC;ADRA1A;BCR GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:1903351| DRD1;ABL1 GO:0030900| forebrain development SRC;DRD2 GO:0050715| positive regulation of cytokine secretion SRC;HTR2B 6773:[DB06616 DB00693] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00693|Fluorescein CYP1A1;SLC22A6;ABCB11;ABCC1 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A1;BCR GO:0009615| response to virus SRC;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0042493| response to drug CYP1A1;LYN;ABCC1;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A1;CYP3A4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP1A1;CYP3A4 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB11;ABCB1 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A1 GO:0008283| cell proliferation SRC;CYP1A1 GO:0002933| CYP2C8;CYP3A4;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;LYN GO:0009636| response to toxin CYP1A1;LYN GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCB11;ABCC1;SLC22A6 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0010033| response to organic substance CYP1A1;CDK2 6774:[DB06616 DB05188] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05188|KD3010 PPARD common genes common pathways GO:0071456| cellular response to hypoxia PPARD;SRC GO:0030154| cell differentiation HCK;CAMK2G;PPARD GO:0006915| apoptotic process PPARD;ABL1 GO:0008283| cell proliferation PPARD;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARD;SRC GO:0010033| response to organic substance CDK2;PPARD GO:0010628| positive regulation of gene expression MAP2K1;SRC;PPARD GO:0042127| regulation of cell proliferation PPARD;ABL1;SRC GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARD GO:0007507| heart development MAP2K1;PPARD GO:0043066| negative regulation of apoptotic process PPARD;HCK;SRC GO:0071222| cellular response to lipopolysaccharide PPARD;ABL1;BCR;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PPARD GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARD;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent PPARD;ABL1 GO:0050728| negative regulation of inflammatory response BCR;PPARD 6775:[DB06616 DB06820] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP2C9;CYP1A2 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP2C9;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP1A2;CYP2D6;CYP2C8 GO:0042738| exogenous drug catabolic process CYP1A2;CYP2C9;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;CYP1A2;LYN GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP1A2;CYP2D6;CYP2C8 GO:0097267| CYP1A2;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development ABL1;CYP1A2 6776:[DB06616 DB00871] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00871|Terbutaline ADRB2;ADRB3;ADRB1;BCHE common genes common pathways GO:0045453| bone resorption SRC;ADRB2 GO:0007165| signal transduction ADRB2;LYN;BCR;SRC;ADRB1;MAP2K1;ADRB3 GO:0043547| positive regulation of GTPase activity ADRB1;BCR GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;MAP2K2;SRC;ADRB2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0042493| response to drug SRC;ABCB1;LYN;BCHE 6777:[DB06616 DB00933] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042493| response to drug ABCB1;SRC;DRD2;HTR2A;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;LYN;ABL1;SRC GO:0016032| viral reproduction LYN;HTR2A;HCK;SRC GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0048678| response to axon injury DRD2;LYN GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;HTR2A GO:0035556| intracellular signal transduction LYN;CAMK2G;DRD2;SRC;BCR GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;DRD2;ABL1;HTR2A GO:0009636| response to toxin DRD2;LYN GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0030336| negative regulation of cell migration BCR;DRD2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;HTR2A GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction BCR;DRD2;SRC;MAP2K1;LYN;HTR2A GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6 GO:0030900| forebrain development DRD2;SRC GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 6778:[DB06616 DB00500] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0070542| response to fatty acid SRC;PTGS2 GO:0006979| response to oxidative stress MPO;PTGS1;ABL1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat PTGS2;LYN GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0009612| response to mechanical stimulus MPO;SRC GO:0043066| negative regulation of apoptotic process PTGS2;MPO;SRC;HCK;ALB GO:0050727| regulation of inflammatory response PTGS2;LYN;HCK GO:0002576| platelet degranulation LYN;ALB GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0008284| positive regulation of cell proliferation LYN;CDK2;PTGS2;HCK GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;MPO;BCR GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;HCK;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process PTGS2;TDO2;CYP3A4;MPO;PTGS1;CYP2C8 GO:0042493| response to drug SRC;ABCB1;LYN;PTGS2 6779:[DB06616 DB13869] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways GO:0060065| uterus development ESR1;SRC GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;ESR2 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;ESR1;MAP2K1;SRC;MAP2K2;ESR2 GO:0010629| negative regulation of gene expression ESR1;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0007165| signal transduction LYN;ESR1;ESR2;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC 6780:[DB06616 DB08143] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08143|5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE F10 common genes common pathways GO:0007596| blood coagulation F10;LYN GO:0030335| positive regulation of cell migration LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;F10 6781:[DB06616 DB00804] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0006464| protein modification process CHRM1;ABL1 GO:0010033| response to organic substance CYP1A1;CDK2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0008283| cell proliferation SRC;CYP1A1;CHRM1 GO:0014070| response to organic cyclic compound CYP1A1;LYN GO:0009636| response to toxin CYP1A1;LYN GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A1;CYP3A4 GO:0007165| signal transduction CHRM2;LYN;CHRM1;MAP2K1;SRC;BCR GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP1A1;CYP3A4 GO:0042493| response to drug CYP1A1;LYN;ABCB1;SRC GO:0007399| nervous system development CAMK2G;CHRM1;CHRM2 GO:0009615| response to virus CYP1A1;CHRM2;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CHRM1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0032496| response to lipopolysaccharide CYP1A1;BCR GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 6782:[DB06616 DB02820] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HSD17B10 GO:0055114| oxidation-reduction process HSD17B10;CYP3A4;CYP2C8 6783:[DB06616 DB02155] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02155|Balanol Analog 8 PRKACA common genes common pathways GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;PRKACA GO:0018105| peptidyl-serine phosphorylation CDK2;PRKACA;CAMK2G;SRC GO:0043393| regulation of protein binding PRKACA;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;PRKACA;SRC GO:0000086| G2/M transition of mitotic cell cycle PRKACA;CDK2;ABCB1 GO:0007596| blood coagulation LYN;PRKACA GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;PRKACA;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0034605| cellular response to heat LYN;PRKACA GO:0016310| phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;PRKACA;CDK2;LYN;CAMK2G;MAP3K2 6784:[DB06616 DB09498] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09498|Strontium chloride Sr-89 ALPPL2;ALPL;SLC8A1;CACNA1I common genes common pathways GO:0032496| response to lipopolysaccharide BCR;ALPL GO:0042542| response to hydrogen peroxide SRC;SLC8A1 GO:0042493| response to drug SRC;SLC8A1;ABCB1;LYN GO:0006816| calcium ion transport SLC8A1;CACNA1I;CAMK2G GO:0051924| regulation of calcium ion transport SLC8A1;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;SLC8A1 GO:0071456| cellular response to hypoxia SRC;SLC8A1 GO:0006810| transport ABCB1;CACNA1I GO:0007165| signal transduction BCR;SRC;CACNA1I;MAP2K1;LYN GO:0055085| transmembrane transport SLC8A1;CACNA1I;ABCB1 GO:0034614| cellular response to reactive oxygen species SLC8A1;SRC 6785:[DB06616 DB00223] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00223|Diflorasone NR3C1 common genes common pathways GO:0051301| cell division NR3C1;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0007049| cell cycle SRC;NR3C1;CDK2 GO:0006915| apoptotic process ABL1;NR3C1 GO:0007165| signal transduction LYN;NR3C1;BCR;SRC;MAP2K1 6786:[DB06616 DB02432] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02432|RU90395 SRC common genes SRC common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;LYN GO:0031954| positive regulation of protein autophosphorylation SRC GO:0038128| SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K1;MAP2K2;SRC GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0038096| LYN;HCK;SRC;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0071803| positive regulation of podosome assembly SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0071498| cellular response to fluid shear stress SRC GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0016032| viral reproduction LYN;SRC;HCK GO:0050900| leukocyte migration LYN;SRC GO:0034332| adherens junction organization SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0016236| macroautophagy SRC GO:0042493| response to drug LYN;ABCB1;SRC GO:0038083| LYN;ABL1;HCK;SRC GO:0031667| response to nutrient levels SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;MAP2K2;SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0045087| innate immune response LYN;ABL1;SRC;HCK GO:0071801| regulation of podosome assembly HCK;SRC GO:0007155| cell adhesion ABL1;HCK;SRC GO:0045124| regulation of bone resorption SRC GO:0051974| negative regulation of telomerase activity SRC GO:0033625| positive regulation of integrin activation SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle BCR;SRC;ABL1 GO:0009615| response to virus SRC GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0060065| uterus development SRC GO:0035556| intracellular signal transduction BCR;SRC;LYN;CAMK2G GO:0071398| cellular response to fatty acid SRC GO:0086098| SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC;LYN GO:0051385| response to mineralocorticoid stimulus SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway SRC;BCR;ABL1 GO:0045056| transcytosis SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0007049| cell cycle CDK2;SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;BCR;SRC;ABL1 GO:0071902| positive regulation of protein serine/threonine kinase activity SRC;MAP2K2;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;SRC;MAP2K2;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1 GO:2000386| positive regulation of ovarian follicle development SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0030900| forebrain development SRC GO:1900182| SRC GO:0031648| protein destabilization SRC GO:1902533| SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0045453| bone resorption SRC GO:0002376| immune system process LYN;SRC;HCK GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0036035| osteoclast development SRC GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;CDK2;LYN GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation SRC;LYN GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0007417| central nervous system development SRC;LYN GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0060491| regulation of cell projection assembly SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC 6787:[DB06616 DB02481] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02481|N-Benzylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ADH1B;CYP2C8 6788:[DB06616 DB00106] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00106|Abarelix GNRHR common genes common pathways GO:0007275| multicellular organismal development CAMK2G;CDK2;GNRHR GO:0007165| signal transduction LYN;GNRHR;MAP2K1;SRC;BCR 6789:[DB06616 DB00014] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00014|Goserelin LHCGR;GNRHR common genes common pathways GO:0007165| signal transduction GNRHR;MAP2K1;SRC;BCR;LYN;LHCGR GO:0001545| primary ovarian follicle growth SRC;LHCGR GO:0007275| multicellular organismal development CDK2;CAMK2G;GNRHR 6790:[DB06616 DB14514] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14514|Magnesium levulinate ATP1A1 common genes common pathways GO:0006813| potassium ion transport ATP1A1;CDK2 GO:0042493| response to drug ATP1A1;LYN;ABCB1;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 6791:[DB06616 DB04278] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways GO:0002376| immune system process IL2;HCK;SRC;LYN GO:0065009| regulation of molecular function IL2;CAMK2G GO:0007204| elevation of cytosolic calcium ion concentration ABL1;IL2 GO:0050728| negative regulation of inflammatory response IL2;BCR GO:0000165| MAPKKK cascade IL2;MAP2K2;MAP2K1;CAMK2G GO:0002250| adaptive immune response LYN;IL2 GO:0001934| positive regulation of protein phosphorylation ABL1;IL2;LYN GO:0043066| negative regulation of apoptotic process IL2;HCK;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;IL2 GO:0007155| cell adhesion SRC;HCK;ABL1;IL2 GO:0001933| negative regulation of protein phosphorylation IL2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IL2 6792:[DB06616 DB04787] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04787|Tanaproget PGR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PGR GO:0010629| negative regulation of gene expression PGR;MAP2K2;MAP2K1 GO:0007165| signal transduction MAP2K1;SRC;BCR;PGR;LYN GO:0050847| progesterone receptor signaling pathway SRC;PGR 6793:[DB06616 DB07001] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07001|(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine NOS3 common genes common pathways GO:0043542| endothelial cell migration NOS3;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0008285| negative regulation of cell proliferation MAP2K1;NOS3;LYN 6794:[DB06616 DB01116] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;BCHE;MAP2K1 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;ABL1 GO:0007165| signal transduction BCR;SRC;CHRNA10;MAP2K1;LYN GO:0042493| response to drug LYN;BCHE;SRC;ABCB1 GO:0006816| calcium ion transport CAMK2G;CHRNA10 GO:0042127| regulation of cell proliferation ABL1;CHRNA10;SRC GO:0042472| inner ear morphogenesis CHRNA10;BCR 6795:[DB06616 DB00729] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00729|Diphemanil Methylsulfate CHRM3 common genes common pathways GO:0007399| nervous system development CAMK2G;CHRM3 GO:0007165| signal transduction CHRM3;LYN;BCR;SRC;MAP2K1 GO:0006464| protein modification process CHRM3;ABL1 GO:0008283| cell proliferation CHRM3;SRC 6796:[DB06616 DB09086] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09086|Eugenol ESR1;ESR2;AR;TRPV3 common genes common pathways GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K1;MAP2K2 GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2;AR;ESR2 GO:0042327| positive regulation of phosphorylation LYN;AR GO:0060065| uterus development ESR1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;AR GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC;ESR2 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0051259| protein oligomerization CAMK2G;AR GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0006816| calcium ion transport CAMK2G;TRPV3 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;ESR2;AR;MAP3K2;CDK2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1;AR;ESR2 GO:0010629| negative regulation of gene expression ESR1;MAP2K1;MAP2K2 GO:0007165| signal transduction BCR;SRC;MAP2K1;AR;ESR2;ESR1;LYN GO:0006810| transport ABCB1;AR GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0055085| transmembrane transport TRPV3;ABCB1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation AR;SRC 6797:[DB06616 DB07675] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0045087| innate immune response SRC;HCK;ABL1;PPARG;LYN GO:0007507| heart development PPARG;MAP2K1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus PPARG;SRC GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG;MAP3K2;MAP2K1;SRC;MAP2K2 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PPARG GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0008285| negative regulation of cell proliferation LYN;PPARG;MAP2K1 GO:0010033| response to organic substance PPARG;CDK2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0014070| response to organic cyclic compound PPARG;LYN 6798:[DB06616 DB05038] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05038|Anatibant BDKRB2 common genes common pathways GO:0006954| inflammatory response HCK;LYN;BDKRB2 GO:0043114| regulation of vascular permeability BCR;SRC;BDKRB2 GO:0007165| signal transduction LYN;BDKRB2;MAP2K1;SRC;BCR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;BDKRB2;HCK GO:0007204| elevation of cytosolic calcium ion concentration ABL1;BDKRB2 6799:[DB06616 DB07250] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07250|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5- TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;EPHB4;LYN GO:0007275| multicellular organismal development EPHB4;CDK2;CAMK2G GO:0007155| cell adhesion EPHB4;ABL1;SRC;HCK GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;EPHB4;CDK2;LYN;MAP3K2 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;EPHB4;CAMK2G;MAP3K2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway HCK;LYN;EPHB4 GO:0048013| ephrin receptor signaling pathway EPHB4;LYN;SRC GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN;EPHB4 6800:[DB06616 DB06213] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06213|Regadenoson ADORA2A common genes common pathways GO:0051924| regulation of calcium ion transport CAMK2G;ADORA2A GO:0050728| negative regulation of inflammatory response ADORA2A;BCR GO:0006954| inflammatory response HCK;ADORA2A;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;ADORA2A GO:0042493| response to drug ADORA2A;LYN;SRC;ABCB1 GO:0006909| phagocytosis ADORA2A;ABL1;HCK GO:0008285| negative regulation of cell proliferation LYN;ADORA2A;MAP2K1 GO:0006915| apoptotic process ADORA2A;ABL1 GO:0007596| blood coagulation ADORA2A;LYN GO:0007165| signal transduction ADORA2A;LYN;SRC;BCR;MAP2K1 GO:0007417| central nervous system development ADORA2A;LYN;SRC 6801:[DB06616 DB09327] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2A6;CYP3A4 GO:0071456| cellular response to hypoxia SRC;SLC29A1 GO:0009636| response to toxin TYMS;LYN GO:0014070| response to organic cyclic compound TYMS;LYN GO:0008283| cell proliferation SLC29A2;SRC GO:0055085| transmembrane transport ABCB1;SLC22A7 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2C8 GO:0042493| response to drug ABCB1;SRC;TYMS;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP2A6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2A6;DPYD;CYP2C8 6802:[DB06616 DB00042] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;VAMP2 GO:0030154| cell differentiation HCK;SYT2;CAMK2G GO:0006887| exocytosis VAMP2;VAMP1;HCK 6803:[DB06616 DB08386] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0007165| signal transduction LYN;PDE10A;MAP2K1;BCR;SRC 6804:[DB06616 DB00891] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00891|Sulfapyridine CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 6805:[DB06616 DB04655] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04655|Metoprine HNMT common genes common pathways GO:0007420| brain development HNMT;BCR 6806:[DB06616 DB08744] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways GO:0055114| oxidation-reduction process NQO2;CYP3A4;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;NQO2;CYP2C8 6807:[DB06616 DB04253] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04253|Tretazicar NQO2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NQO2 GO:0006805| xenobiotic metabolic process CYP2C8;NQO2;CYP3A4 6808:[DB06616 DB06314] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06314|SGX-523 MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;MET GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;MET;CAMK2G GO:0035635| entry of bacterium into host cell SRC;MET GO:0018108| peptidyl-tyrosine phosphorylation MET;LYN;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0008283| cell proliferation SRC;MET GO:0007165| signal transduction MAP2K1;SRC;BCR;MET;LYN GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MET;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;LYN;HCK GO:0006468| protein phosphorylation MET;MAP3K2;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 6809:[DB06616 DB06246] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06246|Exisulind PDE4D;PDE4C;PDE5A;PDE2A;GSTP1;AKR1B1;AKR1B10 common genes common pathways GO:0007417| central nervous system development LYN;SRC;GSTP1 GO:0008202| steroid metabolic process CYP3A4;AKR1B10;CYP2C8 GO:0032869| cellular response to insulin stimulus SRC;GSTP1 GO:0007165| signal transduction PDE4C;SRC;BCR;MAP2K1;LYN;PDE5A;PDE4D;PDE2A GO:0070372| regulation of ERK1 and ERK2 cascade GSTP1;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;GSTP1 GO:0009636| response to toxin GSTP1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;GSTP1;LYN GO:0043200| response to amino acid stimulus GSTP1;LYN GO:0032872| regulation of stress-activated MAPK cascade MAP2K1;GSTP1;MAP2K2 GO:0043407| negative regulation of MAP kinase activity LYN;GSTP1 GO:0043406| positive regulation of MAP kinase activity SRC;PDE5A GO:0010033| response to organic substance CDK2;AKR1B1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ABL1 GO:0034599| cellular response to oxidative stress GSTP1;ABL1 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;GSTP1;ABL1;PDE4D GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;GSTP1;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PDE2A GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1;CYP2C8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;CDK2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PDE2A GO:0014003| oligodendrocyte development LYN;GSTP1 GO:0031667| response to nutrient levels SRC;GSTP1 GO:0050900| leukocyte migration SRC;PDE4D;LYN GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;AKR1B10;CYP2C8 6810:[DB06616 DB11811] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11811|Arhalofenate PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;PPARG;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug PPARG;LYN;SRC;ABCB1 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development MAP2K1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0045087| innate immune response PPARG;LYN;SRC;HCK;ABL1 GO:0009612| response to mechanical stimulus PPARG;SRC GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0014070| response to organic cyclic compound LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG;LYN GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction SRC;BCR;MAP2K1;PPARG;LYN 6811:[DB06616 DB05246] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05246|Methsuximide CACNA1G;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0006816| calcium ion transport CACNA1G;CAMK2G GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0097267| CYP2C19;CYP2C8 GO:0055085| transmembrane transport CACNA1G;ABCB1 6812:[DB06616 DB06096] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06096|NXN-188 NOS1;HTR1B;HTR1D common genes common pathways GO:0051385| response to mineralocorticoid stimulus HTR1B;SRC GO:0055114| oxidation-reduction process NOS1;CYP3A4;CYP2C8 GO:0042493| response to drug LYN;SRC;HTR1B;ABCB1 GO:0042738| exogenous drug catabolic process NOS1;CYP3A4;CYP2C8 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;NOS1;CDK2;MAP3K2 GO:0007165| signal transduction LYN;HTR1D;MAP2K1;SRC;HTR1B;BCR GO:0009636| response to toxin LYN;HTR1D 6813:[DB06616 DB03227] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03227|Nicotinamide Mononucleotide NMNAT1;NMNAT3;BST1;ligA common genes common pathways GO:0050727| regulation of inflammatory response BST1;HCK;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;BST1 GO:0007165| signal transduction MAP2K1;SRC;BST1;BCR;LYN GO:0032956| regulation of actin cytoskeleton organization ABL1;BST1 6814:[DB06616 DB07385] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07385|3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE NQO1 common genes common pathways GO:0051602| response to electrical stimulus NQO1;SRC GO:0055114| oxidation-reduction process CYP3A4;NQO1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;NQO1;CYP3A4 GO:0043066| negative regulation of apoptotic process NQO1;HCK;SRC GO:0070301| cellular response to hydrogen peroxide ABL1;NQO1 GO:0009636| response to toxin LYN;NQO1 GO:0014070| response to organic cyclic compound LYN;NQO1 GO:0006979| response to oxidative stress ABL1;NQO1 6815:[DB06616 DB11254] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0043065| positive regulation of apoptotic process TGM2;SRC;ABL1 GO:0018105| peptidyl-serine phosphorylation TOP1;CDK2;CAMK2G;SRC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TGM2;ABL1 GO:0016032| viral reproduction HCK;SRC;TOP1;LYN GO:0006260| DNA replication TOP1;CDK2 GO:0042493| response to drug ABCB1;SRC;TOP1;LYN GO:0055114| oxidation-reduction process CYP2C8;TYR;CYP3A4 GO:0048538| thymus development MAP2K1;ABL1;TYR GO:0016310| phosphorylation MAP3K2;TOP1;CAMK2G;LYN;CDK2;BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1 GO:0008283| cell proliferation SRC;TYR GO:0045785| positive regulation of cell adhesion TGM2;SRC 6816:[DB06616 DB14700] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;F8;CYP2C8 GO:0002576| platelet degranulation F8;LYN GO:0007596| blood coagulation LYN;F8 GO:0030168| platelet activation LYN;F8;SRC 6817:[DB06616 DB01158] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0042493| response to drug SRC;ABCB1;LYN;ATP1A1 GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 GO:0006813| potassium ion transport ATP1A1;CDK2 6818:[DB06616 DB02336] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02336|RU83876 SRC common genes SRC common pathways GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1 GO:0045785| positive regulation of cell adhesion SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0010954| positive regulation of protein processing SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0001545| primary ovarian follicle growth SRC GO:0008283| cell proliferation SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:0016477| cell migration SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process HCK;SRC;LYN GO:0045453| bone resorption SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0071456| cellular response to hypoxia SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0031295| T cell costimulation SRC;LYN GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development LYN;SRC GO:0036120| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0098609| SRC GO:0060491| regulation of cell projection assembly SRC GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport SRC;MAP2K2;MAP2K1 GO:0038096| ABL1;SRC;HCK;LYN GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071498| cellular response to fluid shear stress SRC GO:0016032| viral reproduction LYN;HCK;SRC GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0050900| leukocyte migration LYN;SRC GO:0034332| adherens junction organization SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0042493| response to drug SRC;ABCB1;LYN GO:0038083| LYN;ABL1;HCK;SRC GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K1;MAP2K2;SRC GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0071801| regulation of podosome assembly HCK;SRC GO:0045087| innate immune response LYN;ABL1;HCK;SRC GO:0007155| cell adhesion ABL1;SRC;HCK GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0051726| regulation of cell cycle ABL1;SRC;BCR GO:0042542| response to hydrogen peroxide SRC GO:0009615| response to virus SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR GO:0071398| cellular response to fatty acid SRC GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0042127| regulation of cell proliferation ABL1;SRC GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;SRC;BCR GO:0045056| transcytosis SRC 6819:[DB06616 DB06752] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06752|Chymopapain PRG2 common genes common pathways GO:0002376| immune system process SRC;HCK;PRG2;LYN 6820:[DB06616 DB09095] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0007165| signal transduction BCR;SRC;MAP2K1;NR3C1;LYN GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0010595| positive regulation of endothelial cell migration ABL1;ANXA3 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007049| cell cycle SRC;CDK2;NR3C1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0006915| apoptotic process NR3C1;ABL1 GO:0002933| CYP2C8;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;CDK2 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0051301| cell division NR3C1;CDK2 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006909| phagocytosis ANXA3;HCK;ABL1 6821:[DB06616 DB02386] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02386|Leucine Phosphonic Acid LAP3 common genes common pathways 6822:[DB06616 DB07903] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07903|3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE METAP1 common genes common pathways 6823:[DB06616 DB06558] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways GO:0032496| response to lipopolysaccharide EDNRB;BCR GO:0043066| negative regulation of apoptotic process EDNRB;HCK;SRC GO:0008284| positive regulation of cell proliferation HCK;EDNRB;CDK2;LYN GO:0071222| cellular response to lipopolysaccharide EDNRB;ABL1;BCR;SRC GO:0007399| nervous system development CAMK2G;EDNRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDNRB;CDK2 GO:0007507| heart development EDNRA;MAP2K1 GO:0001934| positive regulation of protein phosphorylation LYN;EDNRB;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;EDNRB;EDNRA GO:0007165| signal transduction LYN;EDNRA;MAP2K1;BCR;SRC;EDNRB GO:0014070| response to organic cyclic compound LYN;EDNRB GO:0008283| cell proliferation EDNRA;SRC 6824:[DB06616 DB13915] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD19 GO:0050853| B cell receptor signaling pathway ABL1;CD19;LYN GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;CD19 6825:[DB06616 DB06623] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06623|Flupirtine ADRA2A common genes common pathways GO:0032148| activation of protein kinase B activity SRC;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA2A;HCK;CDK2;LYN GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;ADRA2A GO:0030168| platelet activation LYN;ADRA2A;SRC GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0006928| cellular component movement ADRA2A;MAP2K1 6826:[DB06616 DB05793] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05793|PRO-542 FFAR4 common genes common pathways GO:0050728| negative regulation of inflammatory response BCR;FFAR4 GO:0043066| negative regulation of apoptotic process FFAR4;HCK;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade FFAR4;ABL1;MAP2K2;SRC;MAP2K1 GO:0007165| signal transduction FFAR4;LYN;MAP2K1;BCR;SRC 6827:[DB06616 DB09244] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4 GO:0030036| actin cytoskeleton organization BCR;ADRA2A;ABL1 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;HTR1A;LYN;CDK2 GO:0032148| activation of protein kinase B activity SRC;ADRA2A GO:0008283| cell proliferation SRC;HTR1A GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0030168| platelet activation ADRA2A;SRC;LYN GO:0007165| signal transduction LYN;HTR1A;MAP2K1;SRC;BCR;ADRA2A 6828:[DB06616 DB00387] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways GO:0006464| protein modification process ABL1;CHRM1;CHRM3 GO:0008283| cell proliferation CHRM1;CHRM3;CHRM4;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRM4;CHRM1;LYN;CHRM2;CHRM3 GO:0007399| nervous system development CHRM3;CHRM1;CAMK2G;CHRM2 GO:0008284| positive regulation of cell proliferation HCK;CHRM1;LYN;CDK2 GO:0009615| response to virus CHRM2;SRC 6829:[DB06616 DB05133] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05133|VP025 IL1B common genes common pathways GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;IL1B;MAP3K2 GO:0006915| apoptotic process IL1B;ABL1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;IL1B GO:0043407| negative regulation of MAP kinase activity LYN;IL1B GO:0050766| positive regulation of phagocytosis BCR;IL1B GO:0008285| negative regulation of cell proliferation LYN;IL1B;MAP2K1 GO:0030335| positive regulation of cell migration LYN;IL1B GO:0007165| signal transduction MAP2K1;BCR;SRC;IL1B;LYN GO:0070372| regulation of ERK1 and ERK2 cascade IL1B;LYN GO:0045893| positive regulation of transcription, DNA-dependent IL1B;MAP2K1;MAP2K2;SRC;CDK2;MAP3K2 GO:0050900| leukocyte migration IL1B;SRC;LYN GO:0001934| positive regulation of protein phosphorylation LYN;IL1B;ABL1 GO:0006954| inflammatory response LYN;HCK;IL1B GO:0019221| cytokine-mediated signaling pathway HCK;IL1B GO:0009743| response to carbohydrate stimulus IL1B;LYN GO:0000165| MAPKKK cascade IL1B;MAP2K2;MAP2K1;CAMK2G GO:0032496| response to lipopolysaccharide IL1B;BCR GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IL1B GO:0008284| positive regulation of cell proliferation HCK;IL1B;LYN;CDK2 GO:0031663| lipopolysaccharide-mediated signaling pathway IL1B;HCK;LYN GO:0071260| cellular response to mechanical stimulus MAP3K2;IL1B 6830:[DB06616 DB01235] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0030154| cell differentiation CAMK2G;HCK;SLC7A5 GO:0006810| transport SLC7A5;ABCB1;SLC7A8;SLC15A1 GO:0030335| positive regulation of cell migration DRD1;LYN GO:0007165| signal transduction DRD1;DRD5;MAP2K1;DRD2;SRC;BCR;DRD3;LYN;DRD4 GO:0030900| forebrain development DRD2;SRC GO:1903351| DRD1;ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0055085| transmembrane transport SLC16A10;SLC15A1;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;DRD2;SRC;MAP2K1 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;DRD4;MAP3K2 GO:0009636| response to toxin DRD2;DDC;LYN;SLC7A8 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;DRD2 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0010628| positive regulation of gene expression DRD1;MAP2K1;SRC GO:0007275| multicellular organismal development CDK2;CAMK2G;SLC7A5 GO:0048678| response to axon injury DRD2;LYN GO:0001932| regulation of protein phosphorylation LYN;MAP2K1;DRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;CDK2 GO:0007399| nervous system development CAMK2G;SLC7A5 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DRD3 GO:0035556| intracellular signal transduction SRC;DRD2;BCR;CAMK2G;LYN GO:0050900| leukocyte migration SRC;SLC7A5;LYN;SLC7A8 GO:0042493| response to drug LYN;DRD3;ABCB1;DRD2;SRC;DRD1 6831:[DB06616 DB03742] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03742|Compound 4-D ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0007165| signal transduction SRC;BCR;MAP2K1;ESR1;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;MAP2K2;SRC;MAP2K1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0050727| regulation of inflammatory response LYN;ESR1;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0060065| uterus development ESR1;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K2;MAP2K1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 6832:[DB06616 DB01278] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration CALCR;ABL1 GO:0007165| signal transduction LYN;CALCR;BCR;SRC;MAP2K1 GO:2000352| negative regulation of endothelial cell apoptosis RAMP2;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1;RAMP3;CALCR GO:0010628| positive regulation of gene expression RAMP3;CALCR;RAMP2;SRC;MAP2K1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;RAMP3 GO:0007507| heart development MAP2K1;RAMP2 GO:0006816| calcium ion transport CAMK2G;RAMP3;RAMP2;RAMP1 GO:0051897| positive regulation of protein kinase B signaling cascade CALCR;RAMP3;SRC 6833:[DB06616 DB02721] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02721|4-Iodopyrazole ADH1C;ADH1B;ADH1A common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP3A4;ADH1A GO:0055114| oxidation-reduction process CYP3A4;ADH1B;ADH1A;CYP2C8;ADH1C 6834:[DB06616 DB01269] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01269|Panitumumab EGFR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;SRC GO:0000165| MAPKKK cascade EGFR;MAP2K1;MAP2K2;CAMK2G GO:0038128| SRC;EGFR GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;EGFR GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;EGFR;MAP2K1;SRC;MAP2K2 GO:0038083| LYN;ABL1;SRC;HCK;EGFR GO:0001934| positive regulation of protein phosphorylation LYN;EGFR;ABL1 GO:0042327| positive regulation of phosphorylation EGFR;LYN GO:0043066| negative regulation of apoptotic process SRC;EGFR;HCK GO:0035556| intracellular signal transduction BCR;SRC;EGFR;CAMK2G;LYN GO:2000145| regulation of cell motility EGFR;ABL1 GO:0008284| positive regulation of cell proliferation EGFR;HCK;LYN;CDK2 GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0042127| regulation of cell proliferation ABL1;EGFR;SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;MAP2K1;EGFR;HCK;MAP2K2;BCR;SRC GO:0007275| multicellular organismal development CAMK2G;CDK2;EGFR GO:0034614| cellular response to reactive oxygen species SRC;EGFR GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;EGFR;HCK;SRC;BCR GO:0043406| positive regulation of MAP kinase activity EGFR;SRC GO:0014070| response to organic cyclic compound EGFR;LYN GO:0008283| cell proliferation EGFR;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;EGFR;MAP2K1 GO:0006979| response to oxidative stress EGFR;ABL1 GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;LYN GO:0007165| signal transduction EGFR;MAP2K1;SRC;BCR;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;HCK;EGFR GO:0030335| positive regulation of cell migration LYN;EGFR GO:0098609| SRC;EGFR GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;EGFR;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0045930| negative regulation of mitotic cell cycle ABL1;EGFR GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;EGFR;HCK;MAP2K1;SRC;MAP2K2;BCR GO:1903800| EGFR;MAP2K1;MAP2K2 6835:[DB06616 DB09126] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways GO:0001545| primary ovarian follicle growth SRC;LHCGR GO:0007165| signal transduction LHCGR;LYN;BCR;SRC;MAP2K1 6836:[DB06616 DB05369] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05369|HZT-501 HRH2 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;HRH2;LYN 6837:[DB06616 DB01348] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport SLC15A1;SLC15A2;ABCB1 6838:[DB06616 DB00961] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00961|Mepivacaine SCN10A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN10A 6839:[DB06616 DB09186] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09186|Nisoxetine SLC6A4 common genes common pathways GO:0042493| response to drug LYN;ABCB1;SRC;SLC6A4 GO:0051259| protein oligomerization SLC6A4;CAMK2G GO:0071300| cellular response to retinoic acid LYN;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1 GO:0009636| response to toxin LYN;SLC6A4 GO:0010033| response to organic substance SLC6A4;CDK2 GO:0010628| positive regulation of gene expression SLC6A4;SRC;MAP2K1 GO:0007420| brain development SLC6A4;BCR 6840:[DB06616 DB04703] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04703|Hesperidin AURKB common genes common pathways GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1;AURKB GO:0006468| protein phosphorylation AURKB;ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;CDK2;LYN;CAMK2G;MAP3K2 GO:0046777| protein autophosphorylation AURKB;ABL1;SRC;BCR;HCK;CAMK2G;LYN GO:0007049| cell cycle CDK2;SRC;AURKB GO:0008283| cell proliferation SRC;AURKB GO:1901796| CDK2;AURKB GO:0000122| negative regulation of transcription from RNA polymerase II promoter AURKB;CDK2 GO:0051301| cell division AURKB;CDK2 GO:0000278| mitotic cell cycle ABL1;AURKB 6841:[DB06616 DB06825] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06825|Triptorelin GNRHR common genes common pathways GO:0007275| multicellular organismal development GNRHR;CAMK2G;CDK2 GO:0007165| signal transduction GNRHR;MAP2K1;BCR;SRC;LYN 6842:[DB06616 DB07216] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07216|(11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;SRC GO:0042127| regulation of cell proliferation ABL1;SRC;FNTB 6843:[DB06616 DB01941] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RXRB;ABL1 6844:[DB06616 DB01565] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;MAP2K1;MAP2K2 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TRIM13 GO:0032496| response to lipopolysaccharide BCR;OPRM1 GO:0045087| innate immune response TRIM13;ABL1;HCK;SRC;LYN GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K1;SRC;MAP2K2;ABL1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0007165| signal transduction LYN;OPRM1;OPRD1;OPRK1;TRIM13;POMC;SRC;BCR;MAP2K1 6845:[DB06616 DB01694] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01694|D-tartaric acid B3GAT1;TREM1;DDX6;HIF1AN;serA;lpxA;ATP6V1C1;phnA common genes common pathways GO:0035556| intracellular signal transduction SRC;BCR;TREM1;CAMK2G;LYN GO:0045087| innate immune response LYN;TREM1;HCK;SRC;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;HIF1AN GO:0050900| leukocyte migration SRC;TREM1;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HIF1AN 6846:[DB06616 DB07514] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07514|3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one KDR common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation LYN;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;KDR GO:0007275| multicellular organismal development CAMK2G;CDK2;KDR GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0008360| regulation of cell shape KDR;HCK GO:0048010| vascular endothelial growth factor receptor signaling pathway KDR;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;KDR GO:0008284| positive regulation of cell proliferation KDR;HCK;CDK2;LYN GO:0001934| positive regulation of protein phosphorylation KDR;ABL1;LYN GO:0010629| negative regulation of gene expression MAP2K1;KDR;MAP2K2 GO:0038083| LYN;ABL1;SRC;HCK;KDR GO:0016032| viral reproduction SRC;HCK;KDR;LYN GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0006468| protein phosphorylation ABL1;SRC;BCR;MAP2K2;HCK;KDR;MAP2K1;CAMK2G;LYN;CDK2;MAP3K2 GO:0030154| cell differentiation CAMK2G;HCK;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;KDR;HCK GO:0030335| positive regulation of cell migration KDR;LYN GO:0016310| phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;KDR;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;KDR;MAP2K1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0046777| protein autophosphorylation HCK;KDR;SRC;BCR;ABL1;LYN;CAMK2G 6847:[DB06616 DB09270] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes ABCB1 common pathways GO:0055114| oxidation-reduction process CYP3A4;SDHA;HMGCR;NDUFV3;CYP2C8 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;LDLR GO:0042493| response to drug LYN;ABCB1;SRC GO:0016032| viral reproduction HCK;SRC;LDLR;LYN GO:1901529| ABCB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VLDLR;CDK2 GO:0007399| nervous system development SDHA;CAMK2G;VLDLR GO:0006629| lipid metabolic process HMGCR;LDLR;CYP3A4;VLDLR GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HMGCR GO:0071398| cellular response to fatty acid SRC;LDLR GO:0006897| endocytosis ABL1;LDLR;VLDLR GO:0043066| negative regulation of apoptotic process SRC;HCK;HMGCR GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0055085| transmembrane transport ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;ABL1;HMGCR GO:0007411| axon guidance VLDLR;SRC GO:0043407| negative regulation of MAP kinase activity HMGCR;LYN GO:0010628| positive regulation of gene expression LDLR;SRC;MAP2K1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C8;HMGCR;LDLR;VLDLR;CYP3A4 GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;VLDLR 6848:[DB06616 DB12406] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug LYN;CYP1A2;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CDK2 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 6849:[DB06616 DB07393] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways GO:0034599| cellular response to oxidative stress GSR;ABL1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;GSR 6850:[DB06616 DB01839] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01839|Propylene glycol F13A1 common genes common pathways GO:0007596| blood coagulation F13A1;LYN GO:0002576| platelet degranulation F13A1;LYN 6851:[DB06616 DB05675] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05675|EP-2104R FGA common genes common pathways GO:0045087| innate immune response SRC;HCK;FGA;ABL1;LYN GO:0002576| platelet degranulation LYN;FGA GO:0002250| adaptive immune response LYN;FGA GO:0030168| platelet activation LYN;SRC;FGA GO:0007165| signal transduction LYN;MAP2K1;FGA;BCR;SRC GO:0002376| immune system process SRC;HCK;FGA;LYN GO:1900026| ABL1;FGA GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;FGA;MAP2K1;ABL1 GO:0007596| blood coagulation LYN;FGA GO:2000352| negative regulation of endothelial cell apoptosis FGA;ABL1 6852:[DB06616 DB08996] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08996|Dimetacrine ACHE common genes common pathways GO:0006260| DNA replication CDK2;ACHE GO:0007155| cell adhesion ACHE;HCK;SRC;ABL1 GO:0007399| nervous system development ACHE;CAMK2G GO:0008283| cell proliferation ACHE;SRC 6853:[DB06616 DB02262] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHODH GO:0042493| response to drug LYN;ABCB1;SRC;DHODH GO:0043065| positive regulation of apoptotic process DHODH;ABL1;SRC 6854:[DB06616 DB03035] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03035|1,8-Di-Hydroxy-4-Nitro-Anthraquinone CSNK2A1 common genes common pathways GO:0016310| phosphorylation CAMK2G;LYN;CDK2;MAP3K2;CSNK2A1;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 GO:0006468| protein phosphorylation CAMK2G;LYN;CDK2;CSNK2A1;MAP3K2;ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK GO:0007165| signal transduction LYN;CSNK2A1;SRC;BCR;MAP2K1 GO:0018107| peptidyl-threonine phosphorylation CSNK2A1;CAMK2G;MAP2K1 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0007049| cell cycle CSNK2A1;CDK2;SRC GO:0008284| positive regulation of cell proliferation CSNK2A1;LYN;CDK2;HCK GO:1901796| CSNK2A1;CDK2 GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0016236| macroautophagy SRC;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC 6855:[DB06616 DB01135] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01135|Doxacurium CHRNA2;CHRM2;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;BCHE;LYN GO:0007165| signal transduction BCR;SRC;MAP2K1;CHRNA2;LYN;CHRM2 GO:0042493| response to drug LYN;BCHE;ABCB1;SRC GO:0009615| response to virus CHRM2;SRC GO:0007399| nervous system development CHRM2;CAMK2G 6856:[DB06616 DB08084] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08084|IDD594 AKR1B1 common genes common pathways GO:0010033| response to organic substance CDK2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC 6857:[DB06616 DB03222] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03222|dATP POLB;recA;recA common genes common pathways GO:0048536| spleen development POLB;ABL1 GO:0006915| apoptotic process ABL1;POLB GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1;POLB GO:0006281| DNA repair CDK2;ABL1;POLB GO:0006974| response to DNA damage stimulus POLB;ABL1;CDK2;LYN GO:0006260| DNA replication CDK2;POLB GO:0006954| inflammatory response LYN;HCK;POLB GO:0048872| homeostasis of number of cells POLB;BCR 6858:[DB06616 DB04776] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways GO:0008283| cell proliferation SRC;PDXK GO:0016310| phosphorylation ABL1;PDXK;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 6859:[DB06616 DB07379] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways GO:0007049| cell cycle CDK2;CDK6;SRC GO:0008285| negative regulation of cell proliferation CDK6;LYN;MAP2K1 GO:0045646| regulation of erythrocyte differentiation LYN;CDK6 GO:2000773| negative regulation of cellular senescence ABL1;CDK6 GO:0007050| cell cycle arrest MAP2K1;ABL1;CDK6 GO:0007165| signal transduction LYN;CDK6;MAP2K1;BCR;SRC GO:0016310| phosphorylation MAP3K2;CDK6;CAMK2G;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0030154| cell differentiation HCK;CAMK2G;CDK6 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;CDK6;MAP3K2;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0051301| cell division CDK6;CDK2 GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;CDK6 GO:0000082| G1/S transition of mitotic cell cycle CDK6;CAMK2G;CDK2 GO:2000145| regulation of cell motility ABL1;CDK6 GO:0009615| response to virus CDK6;SRC GO:0042127| regulation of cell proliferation ABL1;SRC;CDK6 6860:[DB06616 DB08601] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08601|tributylstannanyl NCOA2;RXRA common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CDK2;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0016032| viral reproduction HCK;SRC;RXRA;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;CDK2;RXRA GO:0007507| heart development MAP2K1;RXRA GO:0045892| negative regulation of transcription, DNA-dependent SRC;NCOA2 6861:[DB06616 DB07645] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways GO:0007596| blood coagulation LYN;HBB GO:0042542| response to hydrogen peroxide HBA1;HBB;SRC 6862:[DB06616 DB04660] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04660|Choline alfoscerate GM2A common genes common pathways GO:0050885| neuromuscular process controlling balance ABL1;BCR;GM2A GO:0006629| lipid metabolic process CYP3A4;GM2A 6863:[DB06616 DB06494] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06494|Sufugolix GNRHR common genes common pathways GO:0007165| signal transduction LYN;GNRHR;SRC;BCR;MAP2K1 GO:0007275| multicellular organismal development GNRHR;CDK2;CAMK2G 6864:[DB06616 DB07108] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC;BCL2L1 GO:2000811| negative regulation of anoikis BCL2L1;SRC GO:0042981| regulation of apoptotic process MAP3K2;MAP2K1;MAP2K2;BCL2L1 GO:0043066| negative regulation of apoptotic process SRC;HCK;BCL2L1 GO:0006897| endocytosis ABL1;BCL2L1 GO:0009615| response to virus BCL2L1;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;BCL2L1 GO:0043065| positive regulation of apoptotic process SRC;BCL2L1;ABL1 GO:0006915| apoptotic process BCL2L1;ABL1 GO:0008283| cell proliferation BCL2L1;SRC GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis BCL2L1;ABL1 6865:[DB06616 DB08642] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4;CYP2C8 6866:[DB06616 DB09409] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways GO:0048013| ephrin receptor signaling pathway LYN;GRIN2B;GRIN1;SRC GO:0006810| transport GRIN2C;GRIN2B;ABCB1;GRIN2A GO:0065009| regulation of molecular function GRIN2A;CAMK2G;GRIN2B;GRIN2C;GRIN2D;GRIN1 GO:0050885| neuromuscular process controlling balance ABL1;BCR;GRIN2C GO:1901216| ABL1;GRIN2B GO:0042493| response to drug ABCB1;SRC;GRIN2A;LYN GO:0000165| MAPKKK cascade GRIN2C;GRIN2D;GRIN1;CAMK2G;GRIN2B;MAP2K1;MAP2K2;GRIN2A GO:0051924| regulation of calcium ion transport CAMK2G;GRIN3B GO:0006816| calcium ion transport GRIN2A;CAMK2G;GRIN3A;GRIN1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;GRIN2A;GRIN1 6867:[DB06616 DB00048] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;COL1A1;SRC;CDK2;MAP3K2 GO:0031667| response to nutrient levels COL1A1;SRC GO:0042493| response to drug LYN;SRC;ABCB1;COL1A1 GO:0050900| leukocyte migration COL1A2;LYN;COL1A1;SRC GO:0042472| inner ear morphogenesis BCR;COL2A1 GO:0071300| cellular response to retinoic acid LYN;COL1A1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;COL1A1 GO:0009612| response to mechanical stimulus COL3A1;SRC;COL1A1 GO:0042542| response to hydrogen peroxide SRC;COL1A1 GO:0071260| cellular response to mechanical stimulus MAP3K2;COL1A1 GO:0050777| negative regulation of immune response LYN;COL3A1 GO:0007507| heart development MAP2K1;COL3A1 GO:0007596| blood coagulation COL1A1;COL1A2;LYN GO:0007179| transforming growth factor beta receptor signaling pathway COL1A2;SRC;COL3A1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway COL1A1;SRC GO:0030335| positive regulation of cell migration COL1A1;LYN GO:0043434| response to peptide hormone stimulus LYN;COL1A1 GO:0007417| central nervous system development SRC;COL2A1;LYN GO:0030168| platelet activation COL1A2;LYN;COL1A1;SRC;COL3A1 GO:0007229| integrin-mediated signaling pathway HCK;COL3A1;SRC;ABL1 6868:[DB06616 DB00102] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00102|Becaplermin PDGFRB;PDGFRA;A2M common genes common pathways GO:0007165| signal transduction LYN;PDGFRB;MAP2K1;BCR;SRC GO:0051056| regulation of small GTPase mediated signal transduction A2M;BCR GO:0032956| regulation of actin cytoskeleton organization PDGFRB;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration PDGFRA;ABL1 GO:0006468| protein phosphorylation ABL1;MAP2K1;PDGFRA;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;PDGFRB;MAP3K2 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway PDGFRB;ABL1 GO:0016310| phosphorylation LYN;CDK2;PDGFRB;CAMK2G;MAP3K2;ABL1;PDGFRA;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0036120| PDGFRB;SRC GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway PDGFRB;LYN;HCK;PDGFRA GO:0043547| positive regulation of GTPase activity BCR;A2M GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;PDGFRB;PDGFRA;SRC GO:0030335| positive regulation of cell migration LYN;PDGFRB;PDGFRA GO:0043406| positive regulation of MAP kinase activity SRC;PDGFRB GO:0014911| positive regulation of smooth muscle cell migration SRC;PDGFRB GO:0046777| protein autophosphorylation CAMK2G;PDGFRB;LYN;ABL1;BCR;SRC;HCK;PDGFRA GO:0034614| cellular response to reactive oxygen species SRC;PDGFRA GO:0070374| positive regulation of ERK1 and ERK2 cascade PDGFRB;ABL1;MAP2K1;PDGFRA;MAP2K2;SRC GO:0009636| response to toxin LYN;PDGFRB GO:0014070| response to organic cyclic compound LYN;PDGFRB GO:0016477| cell migration SRC;PDGFRB GO:0042542| response to hydrogen peroxide PDGFRB;SRC GO:0008284| positive regulation of cell proliferation HCK;PDGFRA;PDGFRB;CDK2;LYN GO:0006935| chemotaxis PDGFRB;PDGFRA;MAP2K1 GO:0043065| positive regulation of apoptotic process PDGFRB;ABL1;SRC GO:0002576| platelet degranulation LYN;A2M GO:0043066| negative regulation of apoptotic process PDGFRB;HCK;SRC GO:2000249| regulation of actin cytoskeleton reorganization PDGFRA;ABL1 GO:0035556| intracellular signal transduction SRC;BCR;PDGFRB;CAMK2G;LYN GO:2000573| positive regulation of DNA biosynthetic process SRC;PDGFRB GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;BCR;SRC;MAP2K1;PDGFRA;HCK;ABL1;PDGFRB;LYN GO:0007275| multicellular organismal development PDGFRA;CAMK2G;PDGFRB;CDK2 GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;PDGFRA;BCR;SRC;PDGFRB GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRA;SRC;PDGFRB GO:0000165| MAPKKK cascade PDGFRB;CAMK2G;MAP2K2;PDGFRA;MAP2K1 GO:0016032| viral reproduction LYN;SRC;PDGFRA;HCK 6869:[DB06616 DB00941] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00941|Hexafluronium BCHE common genes common pathways GO:0042493| response to drug ABCB1;SRC;BCHE;LYN GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE 6870:[DB06616 DB02910] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02910|Octanoyl-Coenzyme A ECHS1;ECI1;ACADM common genes common pathways GO:0006629| lipid metabolic process ECHS1;ECI1;ACADM;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;ACADM;CYP3A4 6871:[DB06616 DB04581] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04581|1-benzylimidazole QPCT common genes common pathways GO:0006464| protein modification process QPCT;ABL1 6872:[DB06616 DB02046] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02046|N-[(Furan-2-Yl)Carbonyl]-(S)-Leucyl-(R)-[1-Amino-2(1h-Indol-3-Yl)Ethyl]-Phosphonic Acid ADAM28 common genes common pathways 6873:[DB06616 DB06264] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06264|Tolperisone CYP1A2 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug SRC;ABCB1;CYP1A2;LYN GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0010033| response to organic substance CDK2;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 6874:[DB06616 DB08378] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08378|4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID MYL6B;MYL12A;MYH7 common genes common pathways GO:0048013| ephrin receptor signaling pathway SRC;MYL12A;LYN 6875:[DB06616 DB01699] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0042493| response to drug ABAT;ABCB1;SRC;LYN 6876:[DB06616 DB06937] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;MAP2K1;SRC;MAP2K2;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent ABL1;ESR2 GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;ESR2 6877:[DB06616 DB07800] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07800|N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation LYN;F10 6878:[DB06616 DB08169] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;LYN GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0042493| response to drug ABCB1;SRC;DHODH;LYN GO:0043065| positive regulation of apoptotic process ABL1;DHODH;SRC 6879:[DB06616 DB06263] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;CDK2;LYN;ABL1 GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;POR GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;POR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CBR1;POR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;POR GO:0042493| response to drug LYN;POR;ABCB1;SRC GO:0017144| drug metabolic process CYP2C8;CBR1;CYP3A4 GO:0030154| cell differentiation CAMK2G;ABCB5;HCK GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0071375| cellular response to peptide hormone stimulus SRC;POR GO:0055085| transmembrane transport ABCB5;ABCB1 GO:0006855| drug transmembrane transport ABCB5;ABCB1 6880:[DB06616 DB08709] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08709|2,3-diphenyl-1H-indole-7-carboxylic acid PIM1 common genes common pathways GO:0016310| phosphorylation ABL1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;PIM1;MAP3K2 GO:0006468| protein phosphorylation HCK;MAP2K1;SRC;MAP2K2;BCR;ABL1;MAP3K2;PIM1;CDK2;LYN;CAMK2G GO:0046777| protein autophosphorylation ABL1;SRC;BCR;HCK;CAMK2G;LYN;PIM1 GO:0007049| cell cycle CDK2;PIM1;SRC GO:0008283| cell proliferation SRC;PIM1 GO:0006915| apoptotic process ABL1;PIM1 GO:0043066| negative regulation of apoptotic process SRC;HCK;PIM1 GO:0007275| multicellular organismal development PIM1;CAMK2G;CDK2 GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;MAP3K2;PIM1 6881:[DB06616 DB03725] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways GO:0032868| response to insulin stimulus PCK1;LYN GO:0032869| cellular response to insulin stimulus SRC;PCK1 GO:0071456| cellular response to hypoxia SRC;PCK1 GO:0006629| lipid metabolic process PCK1;CYP3A4 GO:0071300| cellular response to retinoic acid LYN;PCK1 GO:0032496| response to lipopolysaccharide BCR;PCK1 6882:[DB06616 DB06938] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06938|4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide KDR common genes common pathways GO:0010595| positive regulation of endothelial cell migration KDR;ABL1 GO:0016310| phosphorylation ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1;KDR;CAMK2G;CDK2;LYN;MAP3K2 GO:0030335| positive regulation of cell migration LYN;KDR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway KDR;HCK;LYN GO:0030154| cell differentiation KDR;HCK;CAMK2G GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;HCK;KDR;MAP2K1;SRC;BCR;MAP2K2 GO:0046777| protein autophosphorylation LYN;CAMK2G;HCK;KDR;SRC;BCR;ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade KDR;MAP2K1;MAP2K2;SRC;ABL1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;KDR;HCK GO:0043066| negative regulation of apoptotic process HCK;KDR;SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;KDR GO:0008360| regulation of cell shape KDR;HCK GO:0051894| positive regulation of focal adhesion assembly KDR;ABL1 GO:0007275| multicellular organismal development KDR;CDK2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation LYN;MAP2K2;BCR;SRC;MAP2K1;KDR;HCK;ABL1 GO:0070371| ERK1 and ERK2 cascade MAP2K1;KDR;MAP2K2 GO:0016032| viral reproduction SRC;KDR;HCK;LYN GO:0010629| negative regulation of gene expression MAP2K2;KDR;MAP2K1 GO:0038083| LYN;ABL1;KDR;HCK;SRC GO:0001934| positive regulation of protein phosphorylation KDR;ABL1;LYN 6883:[DB06616 DB05710] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways GO:0007399| nervous system development CHRNA3;CAMK2G GO:0007165| signal transduction LYN;CHRNA3;SRC;BCR;MAP2K1 6884:[DB06616 DB06809] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06809|Plerixafor CXCR4 common genes common pathways GO:0009615| response to virus SRC;CXCR4 GO:0006935| chemotaxis MAP2K1;CXCR4 GO:0006954| inflammatory response LYN;CXCR4;HCK GO:0016032| viral reproduction SRC;HCK;CXCR4;LYN GO:0007204| elevation of cytosolic calcium ion concentration CXCR4;ABL1 GO:0007165| signal transduction MAP2K1;BCR;SRC;CXCR4;LYN GO:0006915| apoptotic process ABL1;CXCR4 GO:0000187| activation of MAPK activity MAP3K2;CXCR4;MAP2K1;MAP2K2 GO:0007411| axon guidance SRC;CXCR4 6885:[DB06616 DB02740] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02740|3-Indolebutyric Acid tyrB;B2M;TRAC;TRBC1;HLA-A common genes common pathways GO:0016032| viral reproduction HLA-A;HCK;SRC;LYN GO:0042493| response to drug ABCB1;SRC;LYN;B2M GO:0071222| cellular response to lipopolysaccharide B2M;ABL1;BCR;SRC GO:0045087| innate immune response LYN;B2M;ABL1;SRC;TRBC1;HCK GO:0050853| B cell receptor signaling pathway LYN;ABL1;TRBC1 GO:0050690| regulation of defense response to virus by virus HCK;B2M GO:0045646| regulation of erythrocyte differentiation B2M;LYN GO:0002376| immune system process B2M;LYN;HCK;SRC;HLA-A GO:0060333| interferon-gamma-mediated signaling pathway HCK;HLA-A;CAMK2G;B2M GO:0031295| T cell costimulation LYN;SRC;TRBC1;TRAC 6886:[DB06616 DB02165] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways 6887:[DB06616 DB01082] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways GO:0045087| innate immune response LYN;PADI4;ABL1;HCK;SRC GO:0006355| regulation of transcription, DNA-dependent PADI4;ABL1 GO:0002376| immune system process LYN;PADI4;HCK;SRC GO:0006464| protein modification process PADI4;ABL1 GO:0055085| transmembrane transport SLC22A6;ABCB1 6888:[DB06616 DB02824] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways GO:0009615| response to virus ODC1;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;ODC1 6889:[DB06616 DB06757] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0043434| response to peptide hormone stimulus LYN;ARG1 GO:0002376| immune system process ARG1;HCK;SRC;LYN GO:0043200| response to amino acid stimulus LYN;ARG1 GO:0006470| protein dephosphorylation TAB1;CAMK2G GO:0038095| TAB1;LYN GO:0007179| transforming growth factor beta receptor signaling pathway SRC;TAB1 GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;TAB1;MAP3K2 GO:0009791| post-embryonic development ACO1;ABL1 GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 GO:0043406| positive regulation of MAP kinase activity TAB1;SRC GO:0032496| response to lipopolysaccharide ARG1;BCR GO:0048678| response to axon injury LYN;ARG1 GO:0002223| stimulatory C-type lectin receptor signaling pathway TAB1;LYN;SRC GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;SRC GO:0071222| cellular response to lipopolysaccharide ABL1;ARG1;BCR;SRC GO:0002576| platelet degranulation LYN;TF GO:0045087| innate immune response ARG1;ABL1;HCK;SRC;LYN GO:0042493| response to drug LYN;ARG1;ABCB1;SRC GO:0055114| oxidation-reduction process CYP2C8;IDH3A;IDH3G;CYP3A4 GO:0002250| adaptive immune response ARG1;LYN 6890:[DB06616 DB14526] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14526|Chromic citrate CYB5A;TF common genes common pathways GO:0002576| platelet degranulation LYN;TF GO:0055114| oxidation-reduction process CYP2C8;CYB5A;CYP3A4 6891:[DB06616 DB00753] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0055085| transmembrane transport KCNA1;ABCB1;CALM1 GO:0038095| LYN;CALM1 GO:0009636| response to toxin LYN;GABRB1 GO:0014070| response to organic cyclic compound MT-ND1;LYN GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;CALM1 GO:0009791| post-embryonic development ABL1;GABRG2 GO:0006810| transport GABRA5;GABRG2;GABRB1;GABRA3;GABRA4;GABRA6;GABRB2;GABRD;GABRA1;ABCB1;GABRB3 GO:0007417| central nervous system development SRC;LYN;GABRA4 GO:0008202| steroid metabolic process CYP2C8;CYP2B6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP2E1;CYP2C8 GO:0007165| signal transduction GABRB3;BCR;CHRNA4;SRC;GRIA1;MAP2K1;ATP2C1;GABRA6;GABRD;LYN;GABRP;GABRE;CHRNB2;GABRB1;GABRA5;GABRQ GO:0007420| brain development GABRA5;KCNA1;BCR GO:0006979| response to oxidative stress CHRNA4;ABL1 GO:0006813| potassium ion transport CDK2;KCNA1 GO:0055114| oxidation-reduction process CYP2C8;MT-ND1;CYP3A4;CYP2E1;CYP2B6 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2B6 GO:0042493| response to drug LYN;CYP2E1;MT-ND1;GABRG3;ABCB1;SRC GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;CALM1;CAMK2G GO:0006816| calcium ion transport CAMK2G;CHRNB2;CHRNA4;ATP2C1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ATP2C1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006281| DNA repair CDK2;CHRNA4;ABL1 GO:0002576| platelet degranulation ALB;CALM1;LYN GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2E1;CYP3A4;CYP2C8 6892:[DB06616 DB01140] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport SLC22A6;SLC15A1;SLC22A5;SLC15A2;SLC22A8;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 6893:[DB06616 DB00121] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways GO:0043542| endothelial cell migration ABL1;CYP1B1 GO:0007155| cell adhesion ABL1;HCK;CYP1B1;SRC GO:0006629| lipid metabolic process PC;ACACB;ACACA;CYP3A4 GO:0043065| positive regulation of apoptotic process CYP1B1;SRC;ABL1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1B1;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1B1;CYP2C8 GO:0010629| negative regulation of gene expression MAP2K2;PC;ACACB;MAP2K1 GO:0042493| response to drug LYN;ABCB1;SRC;ACACB GO:0031667| response to nutrient levels SRC;ACACB GO:0006810| transport SLC5A6;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP1B1 GO:0097267| CYP2C8;CYP1B1 GO:0055085| transmembrane transport SLC5A6;ABCB1 GO:0008283| cell proliferation SRC;HLCS GO:0009636| response to toxin CYP1B1;LYN GO:0014070| response to organic cyclic compound ACACB;LYN GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0008285| negative regulation of cell proliferation LYN;CYP1B1;MAP2K1 GO:0006464| protein modification process ABL1;HLCS GO:0030336| negative regulation of cell migration BCR;CYP1B1 6894:[DB06616 DB05432] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05432|DAS-431 IV CALY common genes common pathways GO:0006897| endocytosis ABL1;CALY 6895:[DB06616 DB05389] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways GO:0007049| cell cycle CDK2;MAEA;SRC GO:0007155| cell adhesion ABL1;SRC;HCK;MAEA GO:0007346| regulation of mitotic cell cycle MAEA;MAP2K1;MAP2K2;MAP3K2 GO:0051301| cell division CDK2;MAEA GO:0006954| inflammatory response HCK;CD163;LYN 6896:[DB06616 DB04901] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04901|Galiximab CD80 common genes common pathways GO:0035556| intracellular signal transduction CD80;LYN;CAMK2G;SRC;BCR GO:0045893| positive regulation of transcription, DNA-dependent CDK2;CD80;MAP3K2;SRC;MAP2K2;MAP2K1 GO:0016032| viral reproduction CD80;LYN;HCK;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;LYN;SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80 GO:0031295| T cell costimulation SRC;CD80;LYN 6897:[DB06616 DB06393] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06393|Xaliproden HTR1A common genes common pathways GO:0008283| cell proliferation HTR1A;SRC GO:0007165| signal transduction LYN;HTR1A;MAP2K1;BCR;SRC GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR1A;HCK 6898:[DB06616 DB04173] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04173|Fructose FHIT common genes common pathways GO:0006915| apoptotic process FHIT;ABL1 GO:0006355| regulation of transcription, DNA-dependent FHIT;ABL1 6899:[DB06616 DB12582] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4;NR1I2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;NR1I2;CYP2C9;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;NR1I2;CDK2;MAP2K1;SRC;MAP2K2 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008202| steroid metabolic process CYP2C8;NR1I2;CYP2C9;CYP3A4 GO:0007165| signal transduction LYN;NR1I2;SRC;BCR;MAP2K1 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1I2 GO:0010628| positive regulation of gene expression NR1I2;SRC;MAP2K1 6900:[DB06616 DB04213] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways GO:0010628| positive regulation of gene expression EPHX2;SRC;MAP2K1 GO:0009636| response to toxin EPHX2;LYN GO:0017144| drug metabolic process EPHX2;CYP3A4;CYP2C8 GO:0006954| inflammatory response EPHX2;LYN;HCK GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4;CYP2C8 6901:[DB06616 DB02869] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02869|3-amino-5-phenylpentane CTSV;CTSK common genes common pathways GO:0045453| bone resorption SRC;CTSK GO:0014070| response to organic cyclic compound CTSV;LYN GO:2000249| regulation of actin cytoskeleton reorganization ABL1;CTSV 6902:[DB06616 DB03722] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03722|3,4-Dihydro-5-Methyl-Isoquinolinone PARP1 common genes common pathways GO:1901216| ABL1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ABL1 GO:0006974| response to DNA damage stimulus ABL1;CDK2;LYN;PARP1 GO:0006281| DNA repair CDK2;PARP1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;CDK2 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PARP1 GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;SRC GO:0006915| apoptotic process ABL1;PARP1 GO:1900182| SRC;PARP1 GO:0032869| cellular response to insulin stimulus SRC;PARP1 6903:[DB06616 DB07232] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07232|Veliparib PARP1;PARP2 common genes common pathways GO:0034599| cellular response to oxidative stress PARP1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;SRC GO:0006974| response to DNA damage stimulus PARP1;CDK2;LYN;ABL1 GO:0006281| DNA repair ABL1;CDK2;PARP2;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PARP1 GO:1901216| PARP1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PARP1 GO:0032869| cellular response to insulin stimulus SRC;PARP1 GO:1900182| SRC;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;PARP1 GO:0006915| apoptotic process ABL1;PARP1 6904:[DB06616 DB05855] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05855|Rivanicline CHRNB2;CXCL8 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;CXCL8 GO:0006928| cellular component movement MAP2K1;CXCL8 GO:0007050| cell cycle arrest ABL1;CXCL8;MAP2K1 GO:0007165| signal transduction LYN;CHRNB2;SRC;CXCL8;BCR;MAP2K1 GO:0006816| calcium ion transport CHRNB2;CAMK2G GO:0006954| inflammatory response HCK;CXCL8;LYN GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR;CXCL8 GO:0030155| regulation of cell adhesion CXCL8;ABL1 GO:0006935| chemotaxis MAP2K1;CXCL8 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;CXCL8;BCR 6905:[DB06616 DB13909] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13909|Bismuth subgallate ALB common genes common pathways GO:0043066| negative regulation of apoptotic process HCK;SRC;ALB GO:0002576| platelet degranulation LYN;ALB 6906:[DB06616 DB03893] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;GAPDH GO:0006915| apoptotic process ABL1;GAPDH GO:0050715| positive regulation of cytokine secretion SRC;GAPDH 6907:[DB06616 DB08262] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways GO:0042542| response to hydrogen peroxide SRC;HBB;HBA1 GO:0007596| blood coagulation LYN;HBB 6908:[DB06616 DB08745] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08745|4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE F10 common genes common pathways GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation LYN;F10 GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC 6909:[DB06616 DB01922] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01922|Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam AMY2A;AMY2A common genes common pathways 6910:[DB06616 DB05122] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways GO:0034446| substrate adhesion-dependent cell spreading ITGB7;ABL1;ITGA4;SRC GO:0050900| leukocyte migration ITGB7;LYN;SRC;ITGA4 GO:0006914| autophagy ITGB4;ABL1 GO:0007155| cell adhesion ITGB7;ABL1;ITGB4;HCK;SRC;ITGA4 GO:0048870| cell motility ITGB4;MAP2K1 GO:0007229| integrin-mediated signaling pathway ABL1;ITGB4;HCK;SRC;ITGA4;ITGB7 6911:[DB06616 DB02585] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02585|4-(Hydroxymethyl)Benzamidine PRSS3 common genes common pathways GO:0043542| endothelial cell migration ABL1;PRSS3 6912:[DB06616 DB04065] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0055114| oxidation-reduction process ADH1A;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;ADH1A;CYP2C8 6913:[DB06616 DB04720] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04720|S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0016236| macroautophagy CSNK2A1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;SRC GO:0008284| positive regulation of cell proliferation HCK;CSNK2A1;LYN;CDK2 GO:1901796| CSNK2A1;CDK2 GO:0007049| cell cycle CDK2;CSNK2A1;SRC GO:0018107| peptidyl-threonine phosphorylation CAMK2G;CSNK2A1;MAP2K1 GO:0006915| apoptotic process ABL1;CSNK2A1 GO:0007165| signal transduction LYN;CSNK2A1;BCR;SRC;MAP2K1 GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CSNK2A1;CAMK2G;LYN;CDK2 GO:0006468| protein phosphorylation LYN;CDK2;CAMK2G;MAP3K2;CSNK2A1;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC 6914:[DB06616 DB00844] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;MAP2K1;MAP2K2 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0071222| cellular response to lipopolysaccharide BCR;SRC;OPRK1;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K2;SRC;MAP2K1;ABL1 GO:0032868| response to insulin stimulus OPRK1;LYN GO:0008285| negative regulation of cell proliferation LYN;OPRM1;MAP2K1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0007165| signal transduction OPRK1;MAP2K1;BCR;SRC;LYN;OPRD1;OPRM1 6915:[DB06616 DB07965] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07965|6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)-ethyl]-9H-purine-2-carbonitrile CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 6916:[DB06616 DB08689] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;SDHB;SDHD;SDHA;SDHC;CYP3A4 GO:0007399| nervous system development CAMK2G;SDHA 6917:[DB06616 DB01112] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 6918:[DB06616 DB04453] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04453|4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose AMY2A;AMY2A common genes common pathways 6919:[DB06616 DB00934] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0035556| intracellular signal transduction ADRA1B;SRC;DRD2;ADRA1A;BCR;CAMK2G;LYN GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0002576| platelet degranulation ORM1;LYN GO:0008284| positive regulation of cell proliferation CHRM1;CDK2;LYN;HTR2A;ADRA1D;ADRA2A;HCK GO:0009615| response to virus SRC;CHRM2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0032148| activation of protein kinase B activity SRC;ADRA2A;ADRA2C;ADRA2B GO:0007399| nervous system development CHRM2;CAMK2G;CHRM1;CHRM3 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CDK2;CAMK2G GO:0048678| response to axon injury LYN;DRD2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6 GO:0007265| Ras protein signal transduction CDK2;ADRA2A GO:0016032| viral reproduction HTR2A;LYN;SRC;HCK GO:0006954| inflammatory response HCK;HRH1;ORM1;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;LYN;SRC;ABL1 GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0042493| response to drug HTR2C;ADRA1A;DRD2;SRC;ABCB1;LYN;HTR2A;SLC6A2;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0030900| forebrain development SRC;DRD2 GO:0007165| signal transduction LYN;ADRA2B;HTR2A;CHRM2;CHRM1;ADRA2C;CHRM3;HRH1;ADRA1D;CHRM5;ADRA1B;HTR2C;ADRA2A;MAP2K1;CHRM4;HTR7;BCR;ADRA1A;SRC;DRD2 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP1A2;CYP3A4 GO:0009725| response to hormone stimulus ADRA1A;LYN GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0030168| platelet activation ADRA2C;LYN;ADRA2B;SRC;ADRA2A GO:0006810| transport ABCB1;SLC6A2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ADRA1D;ABL1;ADRA1B;ADRA1A GO:0006928| cellular component movement MAP2K1;ADRA2A GO:0030336| negative regulation of cell migration DRD2;BCR GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;ADRA1A;LYN GO:0010033| response to organic substance CDK2;CYP1A2 GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A;SRC GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0014070| response to organic cyclic compound CYP1A2;LYN GO:0009636| response to toxin LYN;DRD2 GO:0008283| cell proliferation SRC;CHRM4;ADRA1B;CHRM5;ADRA1D;CHRM3;CHRM1 GO:0000187| activation of MAPK activity MAP3K2;ADRA2B;MAP2K2;MAP2K1 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;DRD2;ADRA1A;MAP2K1;HTR2C;ABL1;HTR2A 6920:[DB06616 DB05079] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05079|HY10275 HRH1;HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;HTR2A;LYN GO:0016032| viral reproduction SRC;HCK;HTR2A;LYN GO:0006954| inflammatory response LYN;HRH1;HCK GO:0043114| regulation of vascular permeability HRH1;BCR;SRC GO:0042493| response to drug SRC;ABCB1;LYN;HTR2A GO:0007165| signal transduction HRH1;LYN;HTR2A;MAP2K1;SRC;BCR GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;HTR2A 6921:[DB06616 DB05403] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05403|CEP-1347 MAPK12 common genes common pathways GO:0007049| cell cycle MAPK12;CDK2;SRC GO:0006468| protein phosphorylation CAMK2G;MAPK12;CDK2;LYN;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0016310| phosphorylation ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC;LYN;CDK2;MAPK12;CAMK2G;MAP3K2 GO:0007050| cell cycle arrest MAPK12;ABL1;MAP2K1 GO:0007165| signal transduction MAP2K1;SRC;BCR;MAPK12;LYN GO:0006355| regulation of transcription, DNA-dependent ABL1;MAPK12 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;MAPK12;CAMK2G GO:0006975| DNA damage induced protein phosphorylation ABL1;MAPK12 GO:0051149| positive regulation of muscle cell differentiation MAPK12;ABL1 GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC;MAPK12 GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;MAPK12;CAMK2G 6922:[DB06616 DB05961] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways GO:0002376| immune system process SERPING1;LYN;HCK;SRC GO:0007596| blood coagulation SERPINA5;SERPING1;LYN;SERPINA1 GO:0002576| platelet degranulation SERPINA1;LYN;SERPING1 GO:0045087| innate immune response SERPING1;LYN;SRC;HCK;ABL1 6923:[DB06616 DB04982] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways GO:0006810| transport GRIA3;GRIA4;ABCB1 GO:0007165| signal transduction LYN;GRIA1;MAP2K1;GRIA2;SRC;BCR 6924:[DB06616 DB11386] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11386|Chlorobutanol KCNH2 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCB1 GO:0006813| potassium ion transport KCNH2;CDK2 GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 6925:[DB06616 DB06021] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06021|AV-412 EGFR;ERBB2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation LYN;ERBB2;ABL1;EGFR GO:0006355| regulation of transcription, DNA-dependent ABL1;ERBB2 GO:0038083| LYN;EGFR;HCK;SRC;ABL1 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;EGFR GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;EGFR;MAP2K1;CDK2;MAP3K2 GO:0038128| SRC;EGFR;ERBB2 GO:0051897| positive regulation of protein kinase B signaling cascade ERBB2;SRC;EGFR GO:0000165| MAPKKK cascade MAP2K2;MAP2K1;EGFR;ERBB2;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation LYN;ERBB2;ABL1;MAP2K2;BCR;SRC;MAP2K1;EGFR;HCK GO:0007275| multicellular organismal development EGFR;CAMK2G;CDK2 GO:0042127| regulation of cell proliferation ABL1;EGFR;SRC GO:0007399| nervous system development CAMK2G;ERBB2 GO:0007507| heart development MAP2K1;ERBB2 GO:0071260| cellular response to mechanical stimulus MAP3K2;EGFR GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;EGFR GO:0042327| positive regulation of phosphorylation LYN;EGFR GO:0043066| negative regulation of apoptotic process EGFR;HCK;SRC GO:2000145| regulation of cell motility EGFR;ERBB2;ABL1 GO:0035556| intracellular signal transduction CAMK2G;LYN;BCR;SRC;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;EGFR;MAP2K2;SRC GO:0045785| positive regulation of cell adhesion SRC;ERBB2 GO:0008283| cell proliferation SRC;EGFR;ERBB2 GO:0014070| response to organic cyclic compound LYN;EGFR GO:0043406| positive regulation of MAP kinase activity ERBB2;EGFR;SRC GO:0046777| protein autophosphorylation LYN;CAMK2G;ERBB2;ABL1;HCK;EGFR;BCR;SRC GO:0034614| cellular response to reactive oxygen species EGFR;SRC GO:0010628| positive regulation of gene expression ERBB2;SRC;MAP2K1 GO:0006468| protein phosphorylation ERBB2;ABL1;MAP2K1;EGFR;HCK;BCR;MAP2K2;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:1903800| EGFR;MAP2K1;MAP2K2 GO:0045930| negative regulation of mitotic cell cycle EGFR;ABL1 GO:0000186| activation of MAPKK activity EGFR;MAP3K2 GO:0016310| phosphorylation LYN;CDK2;CAMK2G;MAP3K2;ABL1;ERBB2;EGFR;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway ERBB2;EGFR;HCK;LYN GO:0030335| positive regulation of cell migration LYN;EGFR GO:0098609| EGFR;SRC GO:0043547| positive regulation of GTPase activity BCR;ERBB2 GO:0007165| signal transduction LYN;MAP2K1;EGFR;BCR;SRC;ERBB2 GO:0070372| regulation of ERK1 and ERK2 cascade EGFR;ERBB2;LYN GO:0006979| response to oxidative stress EGFR;ABL1 6926:[DB06616 DB04869] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04869|Olcegepant CALCA;CALCRL common genes common pathways GO:0007165| signal transduction LYN;CALCRL;MAP2K1;BCR;SRC GO:0006468| protein phosphorylation CAMK2G;CALCA;CDK2;LYN;MAP3K2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0007507| heart development CALCRL;MAP2K1 GO:0045087| innate immune response SRC;HCK;ABL1;LYN;CALCA GO:0008284| positive regulation of cell proliferation CDK2;LYN;CALCRL;HCK GO:0043542| endothelial cell migration CALCA;ABL1 GO:0006816| calcium ion transport CAMK2G;CALCRL GO:0050728| negative regulation of inflammatory response BCR;CALCRL 6927:[DB06616 DB13951] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes ABCB1 common pathways GO:0042981| regulation of apoptotic process ESR1;MAP3K2;MAP2K2;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1;CDK2 GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0006629| lipid metabolic process HSD17B1;CYP3A4;CYP11A1 GO:0008284| positive regulation of cell proliferation LYN;CDK2;AR;HCK GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response ESR1;LYN;HCK GO:0060065| uterus development SRC;CYP19A1;ESR1 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0051259| protein oligomerization AR;CAMK2G GO:1901529| ABCB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0055114| oxidation-reduction process CYP11A1;CYP19A1;CYP3A4;HSD17B1;CYP2C8;CYP17A1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006355| regulation of transcription, DNA-dependent NR3C2;AR;ABL1;ESR1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;ESR1 GO:0042493| response to drug SRC;ABCB1;LYN GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CDK2;MAP3K2;AR;MAP2K2;SRC;MAP2K1 GO:0007165| signal transduction LYN;ESR1;MAP2K1;SRC;BCR;AR;NR3C2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0006810| transport ABCB1;AR GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP17A1;CYP2C8;CYP3A4;CYP11A1 GO:0045332| phospholipid translocation ABCB1 GO:0008285| negative regulation of cell proliferation AR;MAP2K1;LYN GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;AR GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation SRC;AR 6928:[DB06616 DB09202] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug SRC;ADRA1A;ABCB1;LYN GO:0030036| actin cytoskeleton organization ADRA2A;ABL1;BCR GO:0007275| multicellular organismal development ADRA1B;ADRA1D;CAMK2G;CDK2 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0032148| activation of protein kinase B activity ADRA2C;ADRA2B;ADRA2A;SRC GO:0035556| intracellular signal transduction CAMK2G;LYN;ADRA1A;SRC;BCR;ADRA1B GO:0008284| positive regulation of cell proliferation HCK;ADRA2A;ADRA1D;CDK2;LYN GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;ADRA1A;SRC;MAP2K2;ABL1 GO:0008283| cell proliferation ADRA1D;SRC;ADRA1B GO:0008285| negative regulation of cell proliferation ADRA1A;MAP2K1;LYN GO:0043406| positive regulation of MAP kinase activity ADRA2A;SRC GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0030168| platelet activation LYN;ADRA2B;ADRA2C;ADRA2A;SRC GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ABL1;ADRA1B GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0007165| signal transduction BCR;SRC;ADRA1A;MAP2K1;ADRA1B;ADRA2A;ADRA1D;ADRA2C;LYN;ADRA2B GO:0009725| response to hormone stimulus ADRA1A;LYN 6929:[DB06616 DB09161] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;SRC;ABCC1;LYN GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 6930:[DB06616 DB00141] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways GO:0016310| phosphorylation ABL1;MAP2K1;NAGK;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0007420| brain development B4GALT2;BCR GO:0006464| protein modification process ABL1;NAGPA GO:0008285| negative regulation of cell proliferation B4GALT1;LYN;MAP2K1 GO:0042127| regulation of cell proliferation SRC;ABL1;B4GALT1 GO:0007399| nervous system development CAMK2G;NAGLU GO:0007155| cell adhesion B4GALT1;HCK;SRC;ABL1 GO:0043065| positive regulation of apoptotic process B4GALT1;ABL1;SRC GO:0050900| leukocyte migration LYN;B4GALT1;SRC 6931:[DB06616 DB03904] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0034332| adherens junction organization CTNNB1;SRC GO:0042493| response to drug CTNNB1;LYN;ABCB1;SRC;ARG1 GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;CTNNB1 GO:0006355| regulation of transcription, DNA-dependent CTNNB1;ABL1 GO:0060440| trachea formation CTNNB1;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2;CTNNB1 GO:0071498| cellular response to fluid shear stress CA2;SRC GO:0002250| adaptive immune response ARG1;LYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTNNB1;ABL1 GO:0048678| response to axon injury ARG1;LYN GO:0042127| regulation of cell proliferation CTNNB1;SRC;ABL1 GO:0032496| response to lipopolysaccharide BCR;ARG1 GO:0051149| positive regulation of muscle cell differentiation CTNNB1;ABL1 GO:0045087| innate immune response LYN;SRC;HCK;ABL1;ARG1 GO:0007155| cell adhesion ABL1;SRC;HCK;CTNNB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;CTNNB1 GO:0007507| heart development CTNNB1;MAP2K1 GO:0007399| nervous system development CAMK2G;CTNNB1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;CTNNB1 GO:0043065| positive regulation of apoptotic process ABL1;SRC;CTNNB1 GO:0008284| positive regulation of cell proliferation HCK;CTNNB1;CDK2;LYN GO:0035635| entry of bacterium into host cell SRC;CTNNB1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ARG1;ABL1 GO:0071560| cellular response to transforming growth factor beta stimulus SRC;ARG1 GO:0055085| transmembrane transport SLC14A2;ABCB1;SLC14A1 GO:0008283| cell proliferation SRC;CTNNB1 GO:0030182| neuron differentiation ABL1;MAP2K1;CTNNB1 GO:0043200| response to amino acid stimulus ARG1;LYN GO:0070301| cellular response to hydrogen peroxide ARG1;ABL1 GO:0008285| negative regulation of cell proliferation MAP2K1;CTNNB1;LYN GO:0010033| response to organic substance CDK2;CA2 GO:0045892| negative regulation of transcription, DNA-dependent CTNNB1;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;CTNNB1 GO:0030154| cell differentiation CTNNB1;CAMK2G;HCK GO:0098609| CTNNB1;SRC GO:0043434| response to peptide hormone stimulus LYN;ARG1 GO:0030900| forebrain development CTNNB1;SRC GO:0030097| hemopoiesis LYN;CTNNB1 GO:0045453| bone resorption SRC;CTNNB1 GO:0002376| immune system process LYN;ARG1;HCK;SRC GO:0048538| thymus development CTNNB1;MAP2K1;ABL1 6932:[DB06616 DB07177] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGR2;PTGR1 6933:[DB06616 DB03793] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0006954| inflammatory response LYN;PRDX5;HCK GO:0050900| leukocyte migration SLC16A1;SRC;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PRDX5 GO:0055114| oxidation-reduction process CYP2C8;DAO;PRDX5;CYP3A4 GO:0043066| negative regulation of apoptotic process SRC;HCK;PRDX5 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0034599| cellular response to oxidative stress PRDX5;ABL1 GO:0034614| cellular response to reactive oxygen species PRDX5;SRC GO:0009636| response to toxin SLC22A8;LYN GO:0055085| transmembrane transport SLCO2B1;SLC16A1;ABCB1;SLC22A8;SLC15A1 GO:0006915| apoptotic process ABL1;PRDX5 GO:0006979| response to oxidative stress PRDX5;ABL1 GO:0006810| transport SLC15A1;ABCB1 6934:[DB06616 DB02925] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02925|Piretanide SLC12A1 common genes common pathways GO:0055085| transmembrane transport SLC12A1;ABCB1 GO:0006813| potassium ion transport SLC12A1;CDK2 GO:0006810| transport SLC12A1;ABCB1 6935:[DB06616 DB08232] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F7;SRC;F3 GO:0019221| cytokine-mediated signaling pathway F3;HCK GO:0031667| response to nutrient levels SRC;F7 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC;F7;F3 GO:0014070| response to organic cyclic compound LYN;F7 GO:0007596| blood coagulation LYN;F3;F7 GO:0009725| response to hormone stimulus F7;LYN GO:0030335| positive regulation of cell migration F3;LYN;F7 6936:[DB06616 DB13501] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0008285| negative regulation of cell proliferation MAP2K1;PTGS2;LYN GO:0010033| response to organic substance PTGS2;CDK2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2;LYN;HCK GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HCK;SRC GO:0006805| xenobiotic metabolic process PTGS1;CYP2C8;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0042493| response to drug SRC;ABCB1;LYN;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0006954| inflammatory response LYN;PTGS2;HCK;PTGS1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 6937:[DB06616 DB02731] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways GO:0042493| response to drug LYN;OXCT1;SRC;ABCB1 GO:0007507| heart development MAP2K1;OXCT1 GO:0009725| response to hormone stimulus LYN;OXCT1 GO:0007420| brain development BCR;OXCT1 6938:[DB06616 DB07984] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C8 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4 GO:0006954| inflammatory response PTGS1;HCK;LYN 6939:[DB06616 DB13892] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13892|Crotalus atrox antivenin PLA2G10;CYP4A11 common genes common pathways GO:0097267| CYP2C8;CYP4A11 GO:0007411| axon guidance PLA2G10;SRC GO:0019373| epoxygenase P450 pathway CYP2C8;CYP4A11 GO:0006629| lipid metabolic process CYP3A4;PLA2G10 GO:0055114| oxidation-reduction process CYP2C8;CYP4A11;CYP3A4 6940:[DB06616 DB07983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;SRC;ABL1 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C8 GO:0006954| inflammatory response LYN;HCK;PTGS1 GO:0006979| response to oxidative stress PTGS1;ABL1 6941:[DB06616 DB01616] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01616|Alverine HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR1A GO:0007165| signal transduction HTR1A;LYN;SRC;BCR;MAP2K1 GO:0008283| cell proliferation HTR1A;SRC 6942:[DB06616 DB07769] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation MAP2K1;AR GO:0042327| positive regulation of phosphorylation AR;LYN GO:0008284| positive regulation of cell proliferation AR;HCK;CDK2;LYN GO:0051259| protein oligomerization CAMK2G;AR GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;SRC;MAP2K2;MAP2K1;AR GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0007165| signal transduction BCR;SRC;MAP2K1;AR;LYN GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway AR;SRC GO:0008283| cell proliferation AR;SRC 6943:[DB06616 DB01250] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01250|Olsalazine TPMT;IFNG common genes common pathways GO:0007050| cell cycle arrest ABL1;IFNG;MAP2K1 GO:0060333| interferon-gamma-mediated signaling pathway HCK;IFNG;CAMK2G GO:0045892| negative regulation of transcription, DNA-dependent IFNG;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;IFNG GO:0006928| cellular component movement MAP2K1;IFNG GO:0071902| positive regulation of protein serine/threonine kinase activity IFNG;SRC;MAP2K2;MAP2K1 GO:0006915| apoptotic process ABL1;IFNG GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;CDK2 GO:0010634| positive regulation of epithelial cell migration IFNG;SRC GO:0009615| response to virus IFNG;SRC GO:0008284| positive regulation of cell proliferation HCK;IFNG;LYN;CDK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein LYN;IFNG GO:0002250| adaptive immune response LYN;IFNG GO:0001934| positive regulation of protein phosphorylation LYN;ABL1;IFNG GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;IFNG 6944:[DB06616 DB00881] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0009636| response to toxin LYN;SLC22A8 GO:0055085| transmembrane transport SLC22A8;SLC15A2;SLC15A1;ABCB1 GO:0006810| transport SLC15A1;SLC15A2;ABCB1 6945:[DB06616 DB07454] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0008283| cell proliferation SRC;AR GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;MAP2K2;SRC;MAP2K1;CDK2;MAP3K2 GO:0006355| regulation of transcription, DNA-dependent AR;ABL1 GO:0051259| protein oligomerization AR;CAMK2G GO:0042327| positive regulation of phosphorylation LYN;AR GO:0008284| positive regulation of cell proliferation HCK;AR;CDK2;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;AR GO:0045597| positive regulation of cell differentiation MAP2K1;AR 6946:[DB06616 DB08489] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08489|N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YL)-SUCCINAMIDE MMP7 common genes common pathways GO:0031667| response to nutrient levels MMP7;SRC GO:0071260| cellular response to mechanical stimulus MAP3K2;MMP7 6947:[DB06616 DB09117] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09117|Paraldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP3A4;CYP2C8 6948:[DB06616 DB00170] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0008283| cell proliferation SRC;CYP1A1 GO:0007596| blood coagulation GGCX;F7;PROC;F2;PROS1;LYN;F10;VKORC1;F9;PROZ GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0043200| response to amino acid stimulus MTHFR;LYN GO:0014070| response to organic cyclic compound NQO1;CYP1A1;LYN;CYP1A2;F7 GO:0009636| response to toxin LYN;NQO1;CYP1A1 GO:0070301| cellular response to hydrogen peroxide NQO1;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2;CYP1A1 GO:0006464| protein modification process ABL1;GGCX GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0030168| platelet activation LYN;SRC;F2 GO:0030335| positive regulation of cell migration F10;LYN;F7 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;CYP2A6;CYP1A1;CYP2E1;CYP3A4 GO:0097267| CYP1A1;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;VKORC1;CYP2E1;CYP1A1;CYP3A4;AOX1;CYP2A6;CYP2C8 GO:0009725| response to hormone stimulus LYN;F7 GO:1900182| F2;SRC GO:0070555| response to interleukin-1 SRC;MTHFR GO:0051281| positive regulation of release of sequestered calcium ion into cytosol F2;ABL1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0006979| response to oxidative stress ABL1;NQO1 GO:0050900| leukocyte migration PROS1;LYN;SRC;F2;PROC GO:0055114| oxidation-reduction process VKORC1L1;CYP2C8;NQO2;MTHFR;XDH;CYP1A2;VKORC1;CYP2A6;AOX1;CYP1A1;NQO1;CYP2E1;CYP3A4 GO:0001934| positive regulation of protein phosphorylation LYN;F2;ABL1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2A6;CYP2C8 GO:0010629| negative regulation of gene expression XDH;MAP2K2;MAP2K1 GO:0042493| response to drug MTHFR;CYP1A2;LYN;CYP1A1;CYP2E1;SRC;ABCB1 GO:0031667| response to nutrient levels F7;SRC GO:0051897| positive regulation of protein kinase B signaling cascade F7;SRC;F10 GO:0050728| negative regulation of inflammatory response PROC;BCR GO:0051602| response to electrical stimulus SRC;NQO1 GO:0034599| cellular response to oxidative stress ABL1;VKORC1L1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0007275| multicellular organismal development CAMK2G;CDK2;F2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A1;CYP1A2 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway F7;SRC GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;BCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0001933| negative regulation of protein phosphorylation LYN;XDH GO:0008360| regulation of cell shape F2;HCK GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0002576| platelet degranulation LYN;PROS1 GO:0009615| response to virus CYP1A1;SRC GO:0008284| positive regulation of cell proliferation CDK2;LYN;F2;HCK GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6;CYP1A1;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;NQO2;NQO1;CYP2E1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process NQO1;SRC;PROC;HCK 6949:[DB06616 DB08577] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent FGFR1;ABL1 GO:0010629| negative regulation of gene expression FGFR1;MAP2K2;MAP2K1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;FGFR1 GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G;FGFR1 GO:0010976| positive regulation of neuron projection development FGFR1;LYN GO:0018108| peptidyl-tyrosine phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;FGFR1;LYN GO:0042127| regulation of cell proliferation SRC;ABL1;FGFR1 GO:0042472| inner ear morphogenesis BCR;FGFR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;FGFR1 GO:0008284| positive regulation of cell proliferation HCK;FGFR1;LYN;CDK2 GO:0016477| cell migration SRC;FGFR1 GO:0043406| positive regulation of MAP kinase activity FGFR1;SRC GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;FGFR1;LYN GO:0006468| protein phosphorylation MAP3K2;CAMK2G;FGFR1;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:0016310| phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G;FGFR1 GO:0007420| brain development BCR;FGFR1 6950:[DB06616 DB07347] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07347|4-(2-Aminoethyl)Benzenesulfonyl Fluoride GAPDH;ATP6V1B2 common genes common pathways GO:0050715| positive regulation of cytokine secretion SRC;GAPDH GO:0006915| apoptotic process GAPDH;ABL1 GO:0055114| oxidation-reduction process CYP2C8;GAPDH;CYP3A4 6951:[DB06616 DB01339] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01339|Vecuronium CHRNA2;ABCB1 common genes ABCB1 common pathways GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0007165| signal transduction LYN;CHRNA2;MAP2K1;SRC;BCR GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug LYN;ABCB1;SRC 6952:[DB06616 DB03891] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03891|1,5-Bis(N-Benzyloxycarbonyl-L-Leucinyl)Carbohydrazide CTSK common genes common pathways GO:0045453| bone resorption CTSK;SRC 6953:[DB06616 DB05214] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05214|KD7040 NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide BCR;NOS2 GO:0042127| regulation of cell proliferation ABL1;SRC;NOS2 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;NOS2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;NOS2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NOS2 6954:[DB06616 DB03468] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03468|1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide PNMT common genes common pathways 6955:[DB06616 DB00587] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00587|Cinalukast CYSLTR1 common genes common pathways GO:0007165| signal transduction MAP2K1;SRC;CYSLTR1;BCR;LYN GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CYSLTR1 GO:0006935| chemotaxis CYSLTR1;MAP2K1 GO:0006816| calcium ion transport CYSLTR1;CAMK2G 6956:[DB06616 DB05939] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05939|MK-0354 GPER1 common genes common pathways GO:0050728| negative regulation of inflammatory response BCR;GPER1 GO:0006954| inflammatory response LYN;HCK;GPER1 GO:0010629| negative regulation of gene expression MAP2K1;GPER1;MAP2K2 GO:0001934| positive regulation of protein phosphorylation LYN;GPER1;ABL1 GO:0043065| positive regulation of apoptotic process GPER1;SRC;ABL1 GO:0008284| positive regulation of cell proliferation HCK;GPER1;LYN;CDK2 GO:0045087| innate immune response LYN;SRC;GPER1;HCK;ABL1 GO:0007399| nervous system development GPER1;CAMK2G GO:0010628| positive regulation of gene expression MAP2K1;GPER1;SRC GO:0071375| cellular response to peptide hormone stimulus SRC;GPER1 GO:0007049| cell cycle SRC;GPER1;CDK2 GO:0008285| negative regulation of cell proliferation GPER1;MAP2K1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;GPER1;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;GPER1;MAP2K2;MAP2K1 GO:0006915| apoptotic process GPER1;ABL1 GO:0002376| immune system process HCK;SRC;GPER1;LYN GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;GPER1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;GPER1 GO:0030335| positive regulation of cell migration LYN;GPER1 GO:0030154| cell differentiation CAMK2G;HCK;GPER1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;GPER1 6957:[DB06616 DB00272] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00272|Betazole HRH2 common genes common pathways GO:0007165| signal transduction SRC;BCR;MAP2K1;HRH2;LYN 6958:[DB06616 DB00952] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;HTR1A GO:0051385| response to mineralocorticoid stimulus SRC;HTR1B GO:0042493| response to drug LYN;ABCB1;HTR1B;SRC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA GO:0007165| signal transduction SRC;HTR1B;BCR;MAP2K1;HTR1F;HTR1D;HTR1A;LYN GO:0009636| response to toxin LYN;HTR1D GO:0008283| cell proliferation SRC;HTR1A 6959:[DB06616 DB12662] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12662|Naveglitazar PPARG common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction PPARG;LYN;SRC;BCR;MAP2K1 GO:0014070| response to organic cyclic compound LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010033| response to organic substance CDK2;PPARG GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response ABL1;HCK;SRC;LYN;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CDK2 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043065| positive regulation of apoptotic process SRC;ABL1;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0042493| response to drug SRC;ABCB1;PPARG;LYN GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;PPARG;CDK2;MAP3K2 6960:[DB06616 DB03179] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03179|Sinapoyl Coenzyme A COMTD1 common genes common pathways 6961:[DB06616 DB11328] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways GO:0050900| leukocyte migration SRC;LYN;PROCR GO:0007596| blood coagulation PROCR;LYN 6962:[DB06616 DB00019] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00019|Pegfilgrastim CSF3R;ELANE common genes common pathways GO:0043406| positive regulation of MAP kinase activity ELANE;SRC GO:0007165| signal transduction CSF3R;LYN;SRC;BCR;MAP2K1 GO:0006909| phagocytosis ABL1;ELANE;HCK GO:0050900| leukocyte migration LYN;ELANE;SRC GO:0050728| negative regulation of inflammatory response ELANE;BCR GO:0019221| cytokine-mediated signaling pathway HCK;CSF3R GO:0032496| response to lipopolysaccharide BCR;ELANE GO:0007155| cell adhesion CSF3R;ABL1;SRC;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter ELANE;CDK2 6963:[DB06616 DB09147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways GO:0042542| response to hydrogen peroxide HBA1;HBB;SRC GO:0007596| blood coagulation HBB;LYN 6964:[DB06616 DB00109] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0042493| response to drug CYP2E1;LYN;SRC;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8 GO:0097267| CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2E1 6965:[DB06616 DB02371] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways GO:0002376| immune system process LYN;C1S;HCK;SRC GO:0045087| innate immune response C1S;LYN;SRC;HCK;ABL1 6966:[DB06616 DB02028] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways GO:0006909| phagocytosis ABL1;TUB;HCK GO:0050766| positive regulation of phagocytosis BCR;TUB GO:0009725| response to hormone stimulus TUB;LYN 6967:[DB06616 DB07209] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0042493| response to drug ABCB1;SRC;PPARG;LYN GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CDK2;MAP3K2;MAP2K2;SRC;MAP2K1 GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response LYN;PPARG;ABL1;HCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043065| positive regulation of apoptotic process PPARG;ABL1;SRC GO:0009612| response to mechanical stimulus SRC;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN GO:0014070| response to organic cyclic compound LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0007165| signal transduction PPARG;LYN;BCR;SRC;MAP2K1 6968:[DB06616 DB08583] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes ABL1 common pathways GO:0002322| B cell proliferation involved in immune response ABL1 GO:0045580| regulation of T cell differentiation ABL1 GO:0033690| positive regulation of osteoblast proliferation ABL1 GO:0006915| apoptotic process ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;SRC;MAP2K2;MAP2K1 GO:0045184| establishment of protein localization ABL1 GO:0071901| negative regulation of protein serine/threonine kinase activity ABL1 GO:0042100| B cell proliferation ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;ABL1 GO:0051496| positive regulation of stress fiber assembly ABL1 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis ABL1 GO:2000352| negative regulation of endothelial cell apoptosis ABL1 GO:0030182| neuron differentiation MAP2K1;ABL1 GO:0006464| protein modification process ABL1 GO:0046632| alpha-beta T cell differentiation ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1 GO:0050798| activated T cell proliferation ABL1 GO:0051444| negative regulation of ubiquitin-protein ligase activity ABL1 GO:0002333| transitional one stage B cell differentiation ABL1 GO:0046777| protein autophosphorylation SRC;BCR;HCK;ABL1;CAMK2G;LYN GO:0009791| post-embryonic development ABL1 GO:1990051| ABL1 GO:1900272| ABL1 GO:0050853| B cell receptor signaling pathway ABL1;LYN GO:0001922| B-1 B cell homeostasis ABL1 GO:0001843| neural tube closure ABL1 GO:0045930| negative regulation of mitotic cell cycle ABL1 GO:0035791| platelet-derived growth factor receptor-beta signaling pathway ABL1 GO:0007229| integrin-mediated signaling pathway ABL1;HCK;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1 GO:0006468| protein phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;MAP2K2;BCR;SRC GO:0072358| cardiovascular system development ABL1 GO:0030100| regulation of endocytosis ABL1 GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:1903053| ABL1 GO:0010595| positive regulation of endothelial cell migration ABL1 GO:0021587| cerebellum morphogenesis ABL1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1 GO:0031113| regulation of microtubule polymerization ABL1 GO:0007050| cell cycle arrest ABL1;MAP2K1 GO:0090135| actin filament branching ABL1 GO:1903351| ABL1 GO:1905555| ABL1 GO:1902715| ABL1 GO:2000773| negative regulation of cellular senescence ABL1 GO:1900026| ABL1 GO:0006979| response to oxidative stress ABL1 GO:2001020| regulation of response to DNA damage stimulus ABL1 GO:0022408| negative regulation of cell-cell adhesion ABL1 GO:0048538| thymus development MAP2K1;ABL1 GO:0032489| regulation of Cdc42 protein signal transduction ABL1 GO:0048536| spleen development ABL1 GO:0032956| regulation of actin cytoskeleton organization ABL1 GO:0006914| autophagy ABL1 GO:0001934| positive regulation of protein phosphorylation LYN;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1 GO:0000278| mitotic cell cycle ABL1 GO:0050885| neuromuscular process controlling balance ABL1;BCR GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1 GO:0010506| regulation of autophagy ABL1 GO:0006909| phagocytosis ABL1;HCK GO:1904531| ABL1 GO:1901216| ABL1 GO:1900042| ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1 GO:2000096| positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway ABL1 GO:0038083| LYN;HCK;SRC;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0030036| actin cytoskeleton organization BCR;ABL1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0060020| Bergmann glial cell differentiation MAP2K1;ABL1 GO:0038096| ABL1;HCK;SRC;LYN GO:1902036| ABL1 GO:0042770| signal transduction in response to DNA damage ABL1 GO:0006298| mismatch repair ABL1 GO:2000251| positive regulation of actin cytoskeleton reorganization HCK;ABL1 GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;MAP2K2;BCR;SRC;ABL1;LYN GO:0043542| endothelial cell migration ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0034599| cellular response to oxidative stress ABL1 GO:0006975| DNA damage induced protein phosphorylation ABL1 GO:0051894| positive regulation of focal adhesion assembly ABL1 GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0038189| ABL1 GO:0051353| positive regulation of oxidoreductase activity ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1 GO:0051149| positive regulation of muscle cell differentiation ABL1 GO:0060563| neuroepithelial cell differentiation ABL1 GO:0045931| positive regulation of mitotic cell cycle ABL1 GO:1905244| ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0030516| regulation of axon extension ABL1 GO:0051882| mitochondrial depolarization ABL1 GO:0006974| response to DNA damage stimulus ABL1;LYN;CDK2 GO:0006281| DNA repair ABL1;CDK2 GO:2000772| regulation of cellular senescence ABL1 GO:0048668| collateral sprouting ABL1 GO:0045087| innate immune response HCK;SRC;ABL1;LYN GO:0007155| cell adhesion HCK;SRC;ABL1 GO:0030035| microspike assembly ABL1 GO:0030155| regulation of cell adhesion ABL1 GO:1900275| ABL1 GO:0006897| endocytosis ABL1 GO:0030514| negative regulation of BMP signaling pathway ABL1 GO:2000145| regulation of cell motility ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1 GO:1904528| ABL1 GO:0071222| cellular response to lipopolysaccharide SRC;BCR;ABL1 GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;SRC 6969:[DB06616 DB00222] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0042493| response to drug SRC;ABCB1;KCNJ11;ABCC8;LYN GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0032496| response to lipopolysaccharide BCR;ABCC8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0055085| transmembrane transport ABCB11;ABCC8;KCNJ11;ABCB1 GO:0032868| response to insulin stimulus LYN;ABCC8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP2C9 GO:0006813| potassium ion transport KCNJ11;ABCC8;CDK2;KCNJ1 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;ABCC8 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9 GO:0006810| transport ABCB1;ABCB11 6970:[DB06616 DB08462] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08462|N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE SRC common genes SRC common pathways GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability SRC;BCR GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration SRC;LYN GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0042493| response to drug SRC;ABCB1;LYN GO:0038083| ABL1;HCK;SRC;LYN GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0071498| cellular response to fluid shear stress SRC GO:0071803| positive regulation of podosome assembly SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0038096| LYN;SRC;HCK;ABL1 GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0010632| regulation of epithelial cell migration SRC GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;ABL1;SRC GO:0031954| positive regulation of protein autophosphorylation SRC GO:2000641| regulation of early endosome to late endosome transport MAP2K2;SRC;MAP2K1 GO:0034446| substrate adhesion-dependent cell spreading ABL1;SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation ABL1;HCK;MAP2K1;SRC;BCR;MAP2K2;LYN GO:0086098| SRC GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0043393| regulation of protein binding SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway SRC;BCR;ABL1 GO:0042127| regulation of cell proliferation SRC;ABL1 GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0033625| positive regulation of integrin activation SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0032148| activation of protein kinase B activity SRC GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0045087| innate immune response SRC;HCK;ABL1;LYN GO:0035556| intracellular signal transduction CAMK2G;LYN;SRC;BCR GO:0071398| cellular response to fatty acid SRC GO:0009612| response to mechanical stimulus SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0043066| negative regulation of apoptotic process HCK;SRC GO:0060065| uterus development SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0018105| peptidyl-serine phosphorylation SRC;CDK2;CAMK2G GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle SRC;BCR;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0007049| cell cycle CDK2;SRC GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway SRC;LYN GO:0010447| response to acidity SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0007411| axon guidance SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1 GO:0046777| protein autophosphorylation LYN;CAMK2G;ABL1;HCK;BCR;SRC GO:0043149| stress fiber assembly SRC GO:0030168| platelet activation LYN;SRC GO:0048477| oogenesis SRC GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;LYN;CDK2 GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0036035| osteoclast development SRC GO:0007229| integrin-mediated signaling pathway ABL1;SRC;HCK GO:0071456| cellular response to hypoxia SRC GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN GO:0060491| regulation of cell projection assembly SRC GO:0007417| central nervous system development LYN;SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0036120| SRC GO:0031295| T cell costimulation LYN;SRC GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;MAP2K2;BCR;SRC;MAP2K1;HCK;ABL1 GO:1900182| SRC GO:0030900| forebrain development SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:0070555| response to interleukin-1 SRC GO:0070542| response to fatty acid SRC GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1 GO:2000386| positive regulation of ovarian follicle development SRC GO:0051222| positive regulation of protein transport SRC GO:0010907| positive regulation of glucose metabolic process SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0007172| signal complex assembly SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0045453| bone resorption SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process LYN;HCK;SRC GO:0032463| negative regulation of protein homooligomerization SRC 6971:[DB06616 DB00721] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0042493| response to drug LYN;MAOB;BCHE;SLC6A3;SRC;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;MAOA;MAOB;CYP3A4 GO:0006816| calcium ion transport CAMK2G;GRIN3A;KCNN4 GO:0032496| response to lipopolysaccharide BCR;MAOB GO:0043065| positive regulation of apoptotic process KCNMA1;ABL1;SRC GO:0009636| response to toxin LYN;MAOB GO:0014070| response to organic cyclic compound LYN;SLC6A3 GO:0055085| transmembrane transport SLC6A3;ABCB1;KCNMA1;SCN10A GO:0008285| negative regulation of cell proliferation BCHE;LYN;MAP2K1 GO:0045332| phospholipid translocation ABCB1;KCNN4 GO:0071456| cellular response to hypoxia KCNMB1;SRC GO:0006813| potassium ion transport KCNMB1;KCNN4;KCNMB4;KCNMB2;CDK2;KCNMA1;KCNN3;KCNN2;KCNMB3;KCNN1 GO:0002376| immune system process HCK;SRC;KCNN4;LYN GO:0065009| regulation of molecular function KCNMB3;KCNMB2;KCNMB4;KCNMB1;CAMK2G GO:0007165| signal transduction HTR3A;CHRNA2;MAP2K1;SRC;BCR;LYN 6972:[DB06616 DB14507] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:1900034| CAMK2G;GSK3B GO:0007165| signal transduction IMPA1;IMPA2;BCR;SRC;MAP2K1;LYN GO:0016310| phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;GSK3B;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0043547| positive regulation of GTPase activity GSK3B;BCR GO:0030154| cell differentiation GSK3B;HCK;CAMK2G GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;GSK3B;MAP3K2;CAMK2G;CDK2;LYN GO:0006810| transport ABCB1;GRIA3 GO:0046777| protein autophosphorylation HCK;BCR;SRC;GSK3B;ABL1;LYN;CAMK2G GO:0010628| positive regulation of gene expression MAP2K1;SRC;GSK3B GO:0031175| neuron projection development LYN;GSK3B GO:0018107| peptidyl-threonine phosphorylation CAMK2G;MAP2K1;GSK3B GO:0018105| peptidyl-serine phosphorylation GSK3B;SRC;CDK2;CAMK2G GO:0035556| intracellular signal transduction BCR;SRC;GSK3B;LYN;CAMK2G GO:0043066| negative regulation of apoptotic process SRC;HCK;GSK3B GO:0042981| regulation of apoptotic process GSK3B;MAP2K1;MAP2K2;MAP3K2 GO:0007399| nervous system development GSK3B;CAMK2G GO:0007275| multicellular organismal development GSK3B;CDK2;CAMK2G GO:1901216| GSK3B;ABL1 6973:[DB06616 DB03932] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03932|LFA703 ITGAL common genes common pathways GO:0098609| SRC;ITGAL GO:0007229| integrin-mediated signaling pathway ITGAL;SRC;HCK;ABL1 GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;ITGAL GO:0006928| cellular component movement ITGAL;MAP2K1 GO:0007155| cell adhesion ITGAL;ABL1;HCK;SRC GO:0006909| phagocytosis ITGAL;HCK;ABL1 GO:0050900| leukocyte migration SRC;ITGAL;LYN GO:0006954| inflammatory response HCK;ITGAL;LYN 6974:[DB06616 DB01195] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP2C9 GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2C9 GO:0006813| potassium ion transport CDK2;KCNH2 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0055085| transmembrane transport SCN5A;SCN4A;ABCB1;KCNH2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 6975:[DB06616 DB11071] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0070542| response to fatty acid PTGS2;SRC GO:0006979| response to oxidative stress PTGS2;ABL1;PTGS1 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation LYN;PTGS2;MAP2K1 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGS2 GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;PTGS1;PTGS2;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0042493| response to drug ABCB1;SRC;LYN;PTGS2 6976:[DB06616 DB08191] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways GO:0042981| regulation of apoptotic process MAP3K2;SGK1;MAP2K2;MAP2K1 GO:0006974| response to DNA damage stimulus ABL1;SGK1;CDK2;LYN GO:0018105| peptidyl-serine phosphorylation SGK1;SRC;CDK2;CAMK2G GO:0035556| intracellular signal transduction SRC;SGK1;BCR;LYN;CAMK2G GO:0042127| regulation of cell proliferation SRC;SGK1;ABL1 GO:0006915| apoptotic process SGK1;ABL1 GO:0051090| regulation of sequence-specific DNA binding transcription factor activity HCK;SGK1 GO:0006468| protein phosphorylation ABL1;SGK1;MAP2K2;BCR;SRC;MAP2K1;HCK;CAMK2G;CDK2;LYN;MAP3K2 GO:0016310| phosphorylation MAP3K2;CAMK2G;CDK2;LYN;SRC;SGK1;MAP2K2;BCR;HCK;MAP2K1;ABL1 6977:[DB06616 DB13257] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes common pathways GO:0006979| response to oxidative stress NDUFS8;PTGS2;CAT;ABL1;MPO;PTGS1 GO:0097267| CYP2C8;CYP4A11 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0008285| negative regulation of cell proliferation FTH1;MAP2K1;PTGS2;LYN GO:0010033| response to organic substance CDK2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0009636| response to toxin LYN;CAT GO:0032868| response to insulin stimulus LYN;CAT GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0042542| response to hydrogen peroxide SRC;CAT GO:0071222| cellular response to lipopolysaccharide NOS2;BCR;SRC;ABL1 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0002576| platelet degranulation TF;LYN GO:0050727| regulation of inflammatory response LYN;PTGS2;HCK GO:0009612| response to mechanical stimulus MPO;SRC GO:0043066| negative regulation of apoptotic process PTGS2;MPO;SRC;HCK;CAT GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0019373| epoxygenase P450 pathway CYP4A11;CYP2C8 GO:0007399| nervous system development SDHA;CAMK2G GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2;MPO;BCR GO:0042127| regulation of cell proliferation NOS2;PTGS2;ABL1;SRC;PTGS1 GO:0001933| negative regulation of protein phosphorylation LYN;XDH GO:0034599| cellular response to oxidative stress CAT;ABL1 GO:0051259| protein oligomerization RRM1;CAMK2G GO:0006954| inflammatory response HCK;PTGS1;LYN;PTGS2 GO:0006260| DNA replication CDK2;RRM1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;PCBD1 GO:0042493| response to drug PTGS2;LYN;SRC;ABCB1;CAT GO:0010629| negative regulation of gene expression NOS2;XDH;MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;CDK2;MAP2K1;SRC;PCBD1;MAP2K2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0055114| oxidation-reduction process CAT;CYP2C8;SUOX;RRM1;CP;TPH1;MPO;PTGS1;PCBD1;P4HA1;FTH1;TMLHE;CYP3A4;NDUFS8;SDHA;NOS2;CYP4A11;PTGS2;XDH GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0000278| mitotic cell cycle RRM1;ABL1 6978:[DB06616 DB05232] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways GO:0007399| nervous system development CAMK2G;SCN8A;SCN2A GO:0055085| transmembrane transport SCN8A;ABCB1;SCN3A;SCN1A;SCN2A 6979:[DB06616 DB03851] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03851|Carbazole Butanoic Acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response FABP4;HCK;LYN GO:0045892| negative regulation of transcription, DNA-dependent FABP4;SRC 6980:[DB06616 DB08478] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug ABCB1;SRC;TYMS;LYN GO:0009636| response to toxin LYN;TYMS GO:0014070| response to organic cyclic compound TYMS;LYN 6981:[DB06616 DB07931] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0010628| positive regulation of gene expression NR1I2;SRC;MAP2K1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;NR1I2;NR1I3 GO:0007165| signal transduction BCR;SRC;MAP2K1;ESR1;LYN;NR1I2;NR1I3 GO:0008202| steroid metabolic process CYP2C8;NR1I2;CYP3A4 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent MAP3K2;ESR1;CDK2;NR1I2;MAP2K2;SRC;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent NR1I3;NR1I2;ESR1;ABL1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;NR1I2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0055114| oxidation-reduction process CYP2C8;AKR1C1;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0060065| uterus development SRC;ESR1 GO:0006805| xenobiotic metabolic process AKR1C1;NR1I2;CYP3A4;CYP2C8 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0050727| regulation of inflammatory response HCK;LYN;ESR1 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 6982:[DB06616 DB05950] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05950|Contulakin-G CACNA1B common genes common pathways GO:0006816| calcium ion transport CAMK2G;CACNA1B GO:0051924| regulation of calcium ion transport CAMK2G;CACNA1B GO:0055085| transmembrane transport CACNA1B;ABCB1 GO:0006810| transport ABCB1;CACNA1B 6983:[DB06616 DB07112] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways GO:0055114| oxidation-reduction process EGLN1;CYP2C8;CYP3A4 GO:0060711| labyrinthine layer development EGLN1;MAP2K1 6984:[DB06616 DB01827] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways GO:0045087| innate immune response LGALS3;LYN;HCK;SRC;ABL1 GO:0030154| cell differentiation CAMK2G;LGALS3;HCK GO:0002376| immune system process LYN;LGALS3;HCK;SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;LGALS3 6985:[DB06616 DB11219] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;AR GO:0008285| negative regulation of cell proliferation MAP2K1;AR;LYN GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC;AR GO:0008283| cell proliferation AR;SRC GO:0007165| signal transduction LYN;ESR1;MAP2K1;SRC;PGR;BCR;ESR2;AR GO:0050847| progesterone receptor signaling pathway PGR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ESR1;ABL1 GO:0006810| transport AR;ABCB1 GO:0010629| negative regulation of gene expression PGR;MAP2K2;MAP2K1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;ABL1;AR;PGR GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;ESR2;AR;MAP3K2;CDK2;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0050727| regulation of inflammatory response HCK;ESR1;LYN GO:0008284| positive regulation of cell proliferation AR;HCK;CDK2;LYN GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC;ESR1 GO:0042327| positive regulation of phosphorylation AR;LYN GO:0060065| uterus development SRC;ESR1 GO:0045597| positive regulation of cell differentiation AR;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR2;ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP3K2;ESR1;MAP2K1;MAP2K2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0051259| protein oligomerization CAMK2G;AR 6986:[DB06616 DB03732] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03732|Etheno-Nadp BST1 common genes common pathways GO:0050727| regulation of inflammatory response HCK;BST1;LYN GO:0008284| positive regulation of cell proliferation CDK2;LYN;HCK;BST1 GO:0007165| signal transduction MAP2K1;SRC;BST1;BCR;LYN GO:0032956| regulation of actin cytoskeleton organization BST1;ABL1 6987:[DB06616 DB05183] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05183|MLN0415 IKBKB common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKB;LYN;SRC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IKBKB GO:0043066| negative regulation of apoptotic process IKBKB;HCK;SRC GO:0009615| response to virus SRC;IKBKB GO:0018105| peptidyl-serine phosphorylation CAMK2G;IKBKB;CDK2;SRC GO:0045087| innate immune response IKBKB;LYN;SRC;HCK;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;CDK2;IKBKB;MAP3K2 GO:0006954| inflammatory response LYN;IKBKB;HCK GO:0016310| phosphorylation MAP3K2;CAMK2G;IKBKB;LYN;CDK2;SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1 GO:0006468| protein phosphorylation MAP3K2;CAMK2G;IKBKB;LYN;CDK2;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0038095| LYN;IKBKB 6988:[DB06616 DB03382] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways GO:0000187| activation of MAPK activity MAP3K2;SOD1;MAP2K2;MAP2K1 GO:0010033| response to organic substance CDK2;SOD1 GO:0006979| response to oxidative stress SOD1;ABL1 GO:0048538| thymus development MAP2K1;ABL1;SOD1 GO:0031667| response to nutrient levels SRC;SOD1 GO:0042493| response to drug SRC;ABCB1;LYN;SOD1 GO:0055114| oxidation-reduction process CYP2C8;SOD1;CYP3A4 GO:0048678| response to axon injury LYN;SOD1 GO:0034599| cellular response to oxidative stress SOD1;ABL1 GO:0043066| negative regulation of apoptotic process SOD1;HCK;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;SOD1 GO:0002576| platelet degranulation LYN;SOD1 GO:0042542| response to hydrogen peroxide SOD1;SRC 6989:[DB06616 DB06637] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0042493| response to drug ABCB1;SRC;LYN;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP3A4 GO:0071732| cellular response to nitric oxide CDK2;KCNC2 GO:0042542| response to hydrogen peroxide SRC;KCNA5 GO:0009612| response to mechanical stimulus KCNA5;SRC GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0051259| protein oligomerization CAMK2G;KCNA2;KCNA5 GO:0010033| response to organic substance KCNA5;CDK2 GO:0009636| response to toxin KCNC2;KCNC1;LYN GO:0014070| response to organic cyclic compound KCNC2;LYN GO:0055085| transmembrane transport KCNB1;KCND1;KCND3;KCNA5;SLC22A2;ABCB1;KCNA10;KCNA7;KCNA1;KCNC1;KCNA4;KCNC2;KCND2;KCNA6;KCNC3;KCNA2;KCNA3;KCNB2 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0006813| potassium ion transport KCNC1;KCNA4;KCNC2;CDK2;KCNC3;KCNA6;KCND2;KCNB2;KCNA3;KCNA2;KCNB1;KCND3;KCND1;KCNA5;KCNA7;KCNA10;KCNA1 GO:0006887| exocytosis KCNB1;HCK GO:0007420| brain development KCNC1;BCR;KCNA1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0065009| regulation of molecular function CAMK2G;KCNA5 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0071456| cellular response to hypoxia SRC;KCND2 6990:[DB06616 DB08790] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 GO:0007165| signal transduction LYN;BCR;SRC;HPGDS;MAP2K1 6991:[DB06616 DB07940] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07940|9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;BCHE GO:0042493| response to drug BCHE;LYN;SRC;ABCB1 6992:[DB06616 DB03935] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;FGF2;LYN GO:0007275| multicellular organismal development FGF2;CAMK2G;CDK2 GO:0007265| Ras protein signal transduction CDK2;FGF2 GO:0007399| nervous system development FGF2;CAMK2G GO:0043066| negative regulation of apoptotic process HCK;SRC;ANXA5 GO:0008284| positive regulation of cell proliferation FGF2;CDK2;LYN;HCK GO:0006935| chemotaxis FGF2;MAP2K1 GO:0002576| platelet degranulation ANXA5;LYN GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;FGF2;MAP3K2 GO:0051897| positive regulation of protein kinase B signaling cascade FGF2;SRC GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;CAMK2G;FGF2 GO:0030154| cell differentiation HCK;CAMK2G;FGF2 GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;FGF2;SRC GO:0072089| stem cell proliferation ABCB1;FGF2 GO:0007165| signal transduction SRC;BCR;MAP2K1;ANXA5;LYN;FGF2 GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;FGF2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;SRC;FGF2 GO:0007596| blood coagulation ANXA5;LYN GO:0010033| response to organic substance ANXA5;CDK2 GO:0043406| positive regulation of MAP kinase activity FGF2;SRC 6993:[DB06616 DB00722] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00722|Lisinopril ACE common genes common pathways 6994:[DB06616 DB01746] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways GO:0007399| nervous system development SLC7A5;CAMK2G GO:0007275| multicellular organismal development CAMK2G;CDK2;SLC7A5 GO:0050900| leukocyte migration LYN;SRC;SLC7A5 GO:0006810| transport ABCB1;SLC7A5 GO:0030154| cell differentiation CAMK2G;SLC7A5;HCK GO:0055085| transmembrane transport SLC16A10;ABCB1 6995:[DB06616 DB08052] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08052|1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes SRC common pathways GO:0098609| SRC GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity LYN;SRC GO:0060491| regulation of cell projection assembly SRC GO:0036120| SRC GO:0051057| positive regulation of small GTPase mediated signal transduction SRC GO:0007417| central nervous system development SRC;LYN GO:0016310| phosphorylation HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1;MAP3K2;CDK2;LYN;CAMK2G GO:0031295| T cell costimulation LYN;SRC GO:0030168| platelet activation LYN;SRC GO:0043149| stress fiber assembly SRC GO:0006468| protein phosphorylation CAMK2G;CDK2;LYN;MAP3K2;ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK GO:0048477| oogenesis SRC GO:0071456| cellular response to hypoxia SRC GO:0007229| integrin-mediated signaling pathway SRC;HCK;ABL1 GO:0036035| osteoclast development SRC GO:0050847| progesterone receptor signaling pathway SRC GO:0032869| cellular response to insulin stimulus SRC GO:0050715| positive regulation of cytokine secretion SRC GO:0007172| signal complex assembly SRC GO:2000394| positive regulation of lamellipodium morphogenesis SRC GO:0032211| negative regulation of telomere maintenance via telomerase SRC GO:0002376| immune system process LYN;HCK;SRC GO:0045453| bone resorption SRC GO:0032463| negative regulation of protein homooligomerization SRC GO:1902533| SRC GO:0031648| protein destabilization SRC GO:1900182| SRC GO:0030900| forebrain development SRC GO:0070542| response to fatty acid SRC GO:0070555| response to interleukin-1 SRC GO:2000386| positive regulation of ovarian follicle development SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN GO:0010907| positive regulation of glucose metabolic process SRC GO:0051222| positive regulation of protein transport SRC GO:0016477| cell migration SRC GO:0060444| branching involved in mammary gland duct morphogenesis SRC GO:2001237| negative regulation of extrinsic apoptotic signaling pathway SRC GO:0008283| cell proliferation SRC GO:0001545| primary ovarian follicle growth SRC GO:0010954| positive regulation of protein processing SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC GO:0045785| positive regulation of cell adhesion SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K2;SRC;MAP2K1 GO:0010628| positive regulation of gene expression SRC;MAP2K1 GO:0071393| cellular response to progesterone stimulus SRC GO:0034614| cellular response to reactive oxygen species SRC GO:0051895| negative regulation of focal adhesion assembly SRC GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K1;SRC;MAP2K2 GO:0046777| protein autophosphorylation BCR;SRC;HCK;ABL1;CAMK2G;LYN GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC GO:0007049| cell cycle SRC;CDK2 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC GO:0014911| positive regulation of smooth muscle cell migration SRC GO:0043406| positive regulation of MAP kinase activity SRC GO:0048013| ephrin receptor signaling pathway LYN;SRC GO:0071375| cellular response to peptide hormone stimulus SRC GO:0007411| axon guidance SRC GO:0022407| regulation of cell-cell adhesion SRC GO:0010447| response to acidity SRC GO:0045056| transcytosis SRC GO:0048008| platelet-derived growth factor receptor signaling pathway BCR;SRC;ABL1 GO:0042127| regulation of cell proliferation ABL1;SRC GO:0010641| positive regulation of platelet-derived growth factor receptor signaling pathway SRC GO:0051385| response to mineralocorticoid stimulus SRC GO:0018108| peptidyl-tyrosine phosphorylation LYN;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:2000573| positive regulation of DNA biosynthetic process SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway LYN;SRC GO:0043393| regulation of protein binding SRC GO:0086098| SRC GO:0071398| cellular response to fatty acid SRC GO:0035556| intracellular signal transduction BCR;SRC;CAMK2G;LYN GO:0060065| uterus development SRC GO:2001286| regulation of caveolin-mediated endocytosis SRC GO:0048010| vascular endothelial growth factor receptor signaling pathway SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC GO:0009612| response to mechanical stimulus SRC GO:0043066| negative regulation of apoptotic process SRC;HCK GO:0043065| positive regulation of apoptotic process SRC;ABL1 GO:0009615| response to virus SRC GO:0042542| response to hydrogen peroxide SRC GO:0051726| regulation of cell cycle ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABL1 GO:0035635| entry of bacterium into host cell SRC GO:0030520| intracellular estrogen receptor signaling pathway SRC GO:0033625| positive regulation of integrin activation SRC GO:0051974| negative regulation of telomerase activity SRC GO:0045124| regulation of bone resorption SRC GO:0045087| innate immune response ABL1;HCK;SRC;LYN GO:0071801| regulation of podosome assembly SRC;HCK GO:0007155| cell adhesion SRC;HCK;ABL1 GO:0032148| activation of protein kinase B activity SRC GO:0010634| positive regulation of epithelial cell migration SRC GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;MAP2K2;SRC;MAP3K2;CDK2 GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC GO:0031667| response to nutrient levels SRC GO:0038083| LYN;ABL1;SRC;HCK GO:0042493| response to drug LYN;ABCB1;SRC GO:0016236| macroautophagy SRC GO:0051902| negative regulation of mitochondrial depolarization SRC GO:0045737| positive regulation of cyclin-dependent protein kinase activity SRC GO:0043114| regulation of vascular permeability BCR;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC GO:0048011| nerve growth factor receptor signaling pathway SRC GO:0034332| adherens junction organization SRC GO:0050900| leukocyte migration LYN;SRC GO:0016032| viral reproduction HCK;SRC;LYN GO:2000811| negative regulation of anoikis SRC GO:0051602| response to electrical stimulus SRC GO:0071498| cellular response to fluid shear stress SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC GO:0046628| positive regulation of insulin receptor signaling pathway SRC GO:0071803| positive regulation of podosome assembly SRC GO:0010632| regulation of epithelial cell migration SRC GO:2001243| negative regulation of intrinsic apoptotic signaling pathway SRC GO:0038096| ABL1;HCK;SRC;LYN GO:0034446| substrate adhesion-dependent cell spreading SRC;ABL1 GO:2000641| regulation of early endosome to late endosome transport MAP2K1;SRC;MAP2K2 GO:0038128| SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;ABL1 GO:0031954| positive regulation of protein autophosphorylation SRC 6996:[DB06616 DB09031] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09031|Miltefosine ABCB1;PLD1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug LYN;SRC;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0006935| chemotaxis MAP2K1;PLD1 GO:0006629| lipid metabolic process CYP3A4;PLD1 GO:0048870| cell motility MAP2K1;PLD1 GO:1901529| ABCB1 GO:0007265| Ras protein signal transduction PLD1;CDK2 6997:[DB06616 DB08429] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways GO:0043542| endothelial cell migration DPP4;ABL1 GO:0007155| cell adhesion DPP4;HCK;SRC;ABL1 GO:0008284| positive regulation of cell proliferation HCK;DPP4;CDK2;LYN GO:0031295| T cell costimulation LYN;DPP4;SRC 6998:[DB06616 DB02217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02217|Dpb-T NT5M common genes common pathways GO:0006260| DNA replication NT5M;CDK2 6999:[DB06616 DB09552] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09552|Thonzonium ATP6V1C1 common genes common pathways 7000:[DB06616 DB03480] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03480|Brequinar Analog DHODH common genes common pathways GO:0014070| response to organic cyclic compound LYN;DHODH GO:0043065| positive regulation of apoptotic process ABL1;DHODH;SRC GO:0042493| response to drug LYN;ABCB1;SRC;DHODH GO:0055114| oxidation-reduction process DHODH;CYP2C8;CYP3A4 7001:[DB06616 DB04531] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04531|Benzylcysteine MGMT common genes common pathways GO:0034599| cellular response to oxidative stress ABL1;MGMT GO:0006281| DNA repair ABL1;MGMT;CDK2 GO:0006974| response to DNA damage stimulus CDK2;LYN;MGMT;ABL1 GO:0043066| negative regulation of apoptotic process HCK;SRC;MGMT GO:0042493| response to drug LYN;MGMT;ABCB1;SRC GO:0009636| response to toxin LYN;MGMT GO:0014070| response to organic cyclic compound LYN;MGMT 7002:[DB06616 DB01625] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01625|Isopropamide CHRM3;CHRM4 common genes common pathways GO:0007165| signal transduction CHRM3;LYN;MAP2K1;CHRM4;BCR;SRC GO:0008283| cell proliferation CHRM3;CHRM4;SRC GO:0006464| protein modification process ABL1;CHRM3 GO:0007399| nervous system development CHRM3;CAMK2G 7003:[DB06616 DB05035] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05035|Eprotirome THRA;THRB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;THRB GO:0030218| erythrocyte differentiation THRA;LYN GO:0006355| regulation of transcription, DNA-dependent THRA;THRB;ABL1 GO:0030878| thyroid gland development MAP2K1;THRA GO:0045892| negative regulation of transcription, DNA-dependent THRB;SRC;THRA 7004:[DB06616 DB00672] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0032868| response to insulin stimulus LYN;ABCC8 GO:0055085| transmembrane transport SLC15A1;ABCC8;SLC15A2;SLC22A6;ABCB1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2C9 GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0007165| signal transduction LYN;ABCC8;MAP2K1;BCR;SRC GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP2C8 GO:0006979| response to oxidative stress PTGS1;ABL1 GO:0006813| potassium ion transport ABCC8;CDK2 GO:0006810| transport ABCB1;SLC15A2;SLC15A1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0006954| inflammatory response LYN;HCK;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8;CYP2C19;PTGS1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0042493| response to drug ABCC8;LYN;SRC;ABCB1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C19;CYP2C8;CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0042127| regulation of cell proliferation SRC;PTGS1;ABL1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0032496| response to lipopolysaccharide BCR;ABCC8 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2C19 7005:[DB06616 DB03782] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03782|N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea PLAU common genes common pathways GO:0042127| regulation of cell proliferation ABL1;PLAU;SRC GO:0006935| chemotaxis MAP2K1;PLAU GO:0030335| positive regulation of cell migration LYN;PLAU GO:0007165| signal transduction PLAU;SRC;BCR;MAP2K1;LYN GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0007596| blood coagulation PLAU;LYN 7006:[DB06616 DB06729] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06729|Sulfaphenazole CYP2C9;CYP2B6;CYP2C8;CYP2D6 common genes CYP2C8 common pathways GO:0006082| organic acid metabolic process CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C8 GO:0042737| drug catabolic process CYP2D6;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP2B6;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4;CYP2B6 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2B6;CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP3A4;CYP2C8;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0002933| CYP2C8;CYP3A4 7007:[DB06616 DB01684] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01684|1-Hydroxy-1-Thio-Glycerol PREP common genes common pathways 7008:[DB06616 DB11079] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PTGS2 GO:0010033| response to organic substance PTGS2;CDK2 GO:0014070| response to organic cyclic compound LYN;PTGS2 GO:0006979| response to oxidative stress PTGS1;ABL1;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006954| inflammatory response PTGS2;LYN;PTGS1;HCK GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0042493| response to drug PTGS2;LYN;SRC;ABCB1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0043065| positive regulation of apoptotic process PTGS2;SRC;ABL1 GO:0050727| regulation of inflammatory response HCK;PTGS2;LYN GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;PTGS2 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K2 GO:0042127| regulation of cell proliferation ABL1;PTGS1;SRC;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;BCR 7009:[DB06616 DB02300] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC GO:0008285| negative regulation of cell proliferation LYN;VDR;MAP2K1 GO:0042359| vitamin D metabolic process CYP3A4;CYP24A1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;VDR GO:0007165| signal transduction BCR;SRC;VDR;MAP2K1;LYN GO:0006979| response to oxidative stress ABL1;MPO GO:0055114| oxidation-reduction process MPO;CYP2C8;CYP24A1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ABL1;VDR GO:0006816| calcium ion transport VDR;CAMK2G GO:0007275| multicellular organismal development CDK2;CAMK2G;VDR GO:0032496| response to lipopolysaccharide BCR;MPO GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;VDR GO:0043066| negative regulation of apoptotic process HCK;SRC;MPO GO:0009612| response to mechanical stimulus SRC;MPO 7010:[DB06616 DB08437] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;SRC;RPL23;RPL11 GO:0008283| cell proliferation RPL23A;SRC GO:0008284| positive regulation of cell proliferation HCK;RPL23;LYN;CDK2 GO:1901796| RPL11;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RPL23;CDK2 7011:[DB06616 DB08313] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08313|nocodazole HPGDS common genes common pathways GO:0007165| signal transduction LYN;HPGDS;SRC;BCR;MAP2K1 GO:0006629| lipid metabolic process HPGDS;CYP3A4 7012:[DB06616 DB04752] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways GO:0010628| positive regulation of gene expression NR5A1;SRC;MAP2K1 GO:0030154| cell differentiation HCK;NR5A1;CAMK2G GO:0006355| regulation of transcription, DNA-dependent NR5A1;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;CDK2;NR5A1;MAP3K2 7013:[DB06616 DB12747] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB12747|Tertomotide TERT common genes common pathways GO:2000352| negative regulation of endothelial cell apoptosis TERT;ABL1 GO:2000773| negative regulation of cellular senescence ABL1;TERT GO:0071456| cellular response to hypoxia TERT;SRC GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;TERT GO:0043066| negative regulation of apoptotic process SRC;HCK;TERT 7014:[DB06616 DB13170] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13170|Plecanatide GUCY1A2 common genes common pathways GO:0007165| signal transduction GUCY1A2;LYN;MAP2K1;SRC;BCR GO:0035556| intracellular signal transduction CAMK2G;GUCY1A2;LYN;SRC;BCR 7015:[DB06616 DB03983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;SUOX;CYP3A4 7016:[DB06616 DB00953] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00953|Rizatriptan HTR1D;HTR1B;HTR1F;MAOA common genes common pathways GO:0009636| response to toxin LYN;HTR1D GO:0007165| signal transduction BCR;HTR1B;SRC;MAP2K1;HTR1F;HTR1D;LYN GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C8 GO:0042493| response to drug SRC;HTR1B;ABCB1;LYN GO:0051385| response to mineralocorticoid stimulus HTR1B;SRC 7017:[DB06616 DB00777] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00777|Propiomazine HRH1;HTR2A;HTR2C;DRD2;DRD1;DRD4;ADRA1A;ADRA1B;ADRA1D;CHRM3;CHRM5;CHRM2;CHRM4;CHRM1 common genes common pathways GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0007165| signal transduction BCR;ADRA1A;SRC;DRD2;MAP2K1;CHRM4;ADRA1B;HTR2C;DRD1;ADRA1D;CHRM5;CHRM3;HRH1;DRD4;CHRM1;LYN;HTR2A;CHRM2 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol DRD1;ABL1 GO:0030900| forebrain development SRC;DRD2 GO:1903351| DRD1;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;HTR2A;ADRA1A;ABL1;ADRA1B GO:0030335| positive regulation of cell migration DRD1;LYN GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0006464| protein modification process ABL1;CHRM3;CHRM1 GO:0008285| negative regulation of cell proliferation MAP2K1;DRD2;ADRA1A;LYN GO:0030336| negative regulation of cell migration DRD2;BCR GO:0010628| positive regulation of gene expression DRD1;MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;HTR2C;MAP2K1;ADRA1A;DRD2;SRC;MAP2K2;HTR2A GO:0000187| activation of MAPK activity MAP2K2;MAP2K1;DRD4;MAP3K2 GO:0006915| apoptotic process ADRA1A;ABL1 GO:0008283| cell proliferation ADRA1B;CHRM4;SRC;CHRM1;CHRM3;CHRM5;ADRA1D GO:0009636| response to toxin LYN;DRD2 GO:0007399| nervous system development CHRM2;CHRM1;CAMK2G;CHRM3 GO:0008284| positive regulation of cell proliferation HCK;ADRA1D;CHRM1;HTR2A;LYN;CDK2 GO:0009615| response to virus SRC;CHRM2 GO:0035556| intracellular signal transduction CAMK2G;LYN;ADRA1B;BCR;SRC;DRD2;ADRA1A GO:0048678| response to axon injury LYN;DRD2 GO:0007275| multicellular organismal development ADRA1D;CDK2;CAMK2G;ADRA1B GO:0001932| regulation of protein phosphorylation MAP2K1;DRD1;LYN GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;ABL1;HTR2A;LYN GO:0006954| inflammatory response HRH1;LYN;HCK GO:0016032| viral reproduction SRC;HCK;LYN;HTR2A GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0042493| response to drug DRD1;HTR2C;ABCB1;ADRA1A;SRC;DRD2;HTR2A;LYN 7018:[DB06616 DB07974] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07974|1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;SRC GO:0030335| positive regulation of cell migration LYN;F10 GO:0007596| blood coagulation F10;LYN 7019:[DB06616 DB13983] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0009791| post-embryonic development GABRG2;ABL1 GO:0007165| signal transduction GABRA5;LYN;GABRA6;MAP2K1;SRC;BCR GO:0007420| brain development BCR;GABRA5 GO:0006810| transport GABRA3;GABRG2;GABRA5;GABRA6;GABRA4;GABRA1;ABCB1 GO:0007417| central nervous system development GABRA4;LYN;SRC GO:0042493| response to drug LYN;ABCB1;SRC;GABRG3 7020:[DB06616 DB08383] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways GO:0007165| signal transduction LYN;MAP2K1;SRC;BCR;PDE10A 7021:[DB06616 DB02895] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways GO:0034599| cellular response to oxidative stress GSR;ABL1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;GSR 7022:[DB06616 DB06766] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06766|Alcaftadine HRH1 common genes common pathways GO:0043114| regulation of vascular permeability BCR;SRC;HRH1 GO:0006954| inflammatory response HRH1;LYN;HCK GO:0007165| signal transduction BCR;SRC;MAP2K1;LYN;HRH1 7023:[DB06616 DB02967] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02967|N-Ethylmaleimide CLC common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;CLC 7024:[DB06616 DB07147] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07147|methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate ADAM17 common genes common pathways GO:0030335| positive regulation of cell migration ADAM17;LYN GO:0048536| spleen development ADAM17;ABL1 GO:0042493| response to drug ABCB1;SRC;ADAM17;LYN GO:0007173| epidermal growth factor receptor signaling pathway ABL1;SRC;ADAM17 GO:0001934| positive regulation of protein phosphorylation LYN;ADAM17;ABL1 GO:0032496| response to lipopolysaccharide BCR;ADAM17 GO:0048870| cell motility MAP2K1;ADAM17 GO:0008284| positive regulation of cell proliferation LYN;CDK2;ADAM17;HCK GO:0051272| positive regulation of cellular component movement ADAM17;LYN GO:0007155| cell adhesion ABL1;HCK;SRC;ADAM17 7025:[DB06616 DB00484] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0030168| platelet activation SRC;ADRA2A;ADRA2C;LYN;ADRA2B GO:0030335| positive regulation of cell migration ADRA2A;LYN GO:0017144| drug metabolic process CYP2C8;AOX1;CYP3A4 GO:0007165| signal transduction ADRA2A;MAP2K1;SRC;BCR;ADRA2B;LYN;ADRA2C GO:0000187| activation of MAPK activity ADRA2B;MAP3K2;MAP2K1;MAP2K2 GO:0043406| positive regulation of MAP kinase activity SRC;ADRA2A GO:0006928| cellular component movement ADRA2A;MAP2K1 GO:0007265| Ras protein signal transduction ADRA2A;CDK2 GO:0032148| activation of protein kinase B activity ADRA2A;SRC;ADRA2C;ADRA2B GO:0008284| positive regulation of cell proliferation LYN;CDK2;HCK;ADRA2A GO:0055114| oxidation-reduction process CYP2C8;AOX1;CYP3A4 GO:0030036| actin cytoskeleton organization BCR;ABL1;ADRA2A 7026:[DB06616 DB01954] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01954|Rolipram PDE4D;PDE4B common genes common pathways GO:0071222| cellular response to lipopolysaccharide PDE4D;SRC;BCR;ABL1;PDE4B GO:0050900| leukocyte migration LYN;PDE4D;PDE4B;SRC GO:0007165| signal transduction PDE4D;LYN;MAP2K1;BCR;SRC;PDE4B 7027:[DB06616 DB08599] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08599|N-[(4-methoxyphenyl)sulfonyl]-D-alanine MMP12 common genes common pathways GO:0010628| positive regulation of gene expression MAP2K1;MMP12;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;MMP12 7028:[DB06616 DB05207] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0051222| positive regulation of protein transport TNF;SRC GO:0007165| signal transduction LYN;SRC;BCR;MAP2K1;IL1R1 GO:0070555| response to interleukin-1 SRC;IL1R1 GO:0050715| positive regulation of cytokine secretion SRC;TNF GO:0045930| negative regulation of mitotic cell cycle ABL1;TNF GO:0043406| positive regulation of MAP kinase activity TNF;SRC GO:0050766| positive regulation of phagocytosis TNF;BCR GO:0045892| negative regulation of transcription, DNA-dependent TNF;SRC GO:0010033| response to organic substance TNF;CDK2 GO:0010628| positive regulation of gene expression TNF;MAP2K1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;MAP2K2;MAP2K1;ABL1;TNF GO:0045785| positive regulation of cell adhesion TNF;SRC GO:0000187| activation of MAPK activity TNF;MAP3K2;MAP2K1;MAP2K2 GO:0008630| DNA damage response, signal transduction resulting in induction of apoptosis TNF;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;CDK2 GO:0071222| cellular response to lipopolysaccharide ABL1;SRC;BCR;TNF GO:0009615| response to virus SRC;TNF GO:0043065| positive regulation of apoptotic process ABL1;SRC;TNF GO:0050727| regulation of inflammatory response LYN;TNF;HCK;IL1R1 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;LYN;HCK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNF GO:0007275| multicellular organismal development CAMK2G;CDK2;TNF GO:0042127| regulation of cell proliferation ABL1;SRC;TNF GO:0001932| regulation of protein phosphorylation LYN;TNF;MAP2K1 GO:0019221| cytokine-mediated signaling pathway IL1R1;HCK GO:0071803| positive regulation of podosome assembly TNF;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNF;SRC GO:0000165| MAPKKK cascade MAP2K1;MAP2K2;TNF;CAMK2G GO:0006954| inflammatory response HCK;TNF;LYN GO:0050900| leukocyte migration TNF;LYN;SRC GO:0001934| positive regulation of protein phosphorylation LYN;TNF;ABL1 GO:0010629| negative regulation of gene expression TNF;MAP2K2;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;TNF;MAP3K2;MAP2K1;SRC;MAP2K2 7029:[DB06616 DB06677] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06677|Clazosentan EDNRA common genes common pathways GO:0007165| signal transduction LYN;EDNRA;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;ABL1 GO:0008283| cell proliferation SRC;EDNRA GO:0007507| heart development MAP2K1;EDNRA 7030:[DB06616 DB04258] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04258|Seocalcitol VDR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;CDK2 GO:0007275| multicellular organismal development VDR;CAMK2G;CDK2 GO:0006816| calcium ion transport VDR;CAMK2G GO:0006355| regulation of transcription, DNA-dependent VDR;ABL1 GO:0007165| signal transduction VDR;MAP2K1;SRC;BCR;LYN GO:0010628| positive regulation of gene expression VDR;MAP2K1;SRC GO:0008285| negative regulation of cell proliferation VDR;MAP2K1;LYN GO:0045892| negative regulation of transcription, DNA-dependent VDR;SRC 7031:[DB06616 DB01188] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K2;ATP1A1 GO:0042493| response to drug LYN;ATP1A1;SRC;ABCB1 GO:0006813| potassium ion transport ATP1A1;CDK2 7032:[DB06616 DB11221] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11221|Dioxybenzone SHBG common genes common pathways 7033:[DB06616 DB06548] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0016032| viral reproduction SRC;HCK;FDPS;LYN GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;FDPS 7034:[DB06616 DB11098] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways GO:0006810| transport SLC12A2;SLC12A1;ABCB1 GO:0006813| potassium ion transport SLC12A1;SLC12A2;CDK2 GO:0055085| transmembrane transport SLC12A1;ABCB1;SLC12A2 7035:[DB06616 DB00045] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00045|Lyme disease vaccine (recombinant OspA) TLR2 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway TLR2;LYN;HCK GO:0045087| innate immune response ABL1;HCK;SRC;LYN;TLR2 GO:0032496| response to lipopolysaccharide TLR2;BCR GO:0050707| regulation of cytokine secretion TLR2;LYN GO:0006954| inflammatory response HCK;LYN;TLR2 GO:0002376| immune system process HCK;SRC;LYN;TLR2 GO:0070542| response to fatty acid TLR2;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;TLR2;LYN GO:0010628| positive regulation of gene expression SRC;MAP2K1;TLR2 GO:0008285| negative regulation of cell proliferation TLR2;LYN;MAP2K1 GO:0009636| response to toxin LYN;TLR2 GO:0006915| apoptotic process ABL1;TLR2 GO:0032868| response to insulin stimulus TLR2;LYN 7036:[DB06616 DB02492] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02492|Ghavamiol MAN2A1 common genes common pathways 7037:[DB06616 DB01944] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01944|(S)-blebbistatin MYH14 common genes common pathways GO:0008360| regulation of cell shape HCK;MYH14 7038:[DB06616 DB04372] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 7039:[DB06616 DB00905] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0055114| oxidation-reduction process AKR1C3;CYP3A4;CYP2C8 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;SRC GO:0032496| response to lipopolysaccharide PTGFR;BCR;PTGER1 GO:0043066| negative regulation of apoptotic process HCK;SRC;PTGFR GO:0008284| positive regulation of cell proliferation CDK2;LYN;AKR1C3;PTGFR;HCK GO:0030216| keratinocyte differentiation AKR1C3;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;PTGFR;SRC GO:0034614| cellular response to reactive oxygen species AKR1C3;SRC GO:0008202| steroid metabolic process CYP3A4;AKR1C3;CYP2C8 GO:0007165| signal transduction LYN;PTGER1;PTGER3;BCR;SRC;PTGFR;MAP2K1 7040:[DB06616 DB00466] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0032496| response to lipopolysaccharide BCR;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0009615| response to virus SRC;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;SRC;LYN;CYP1A1 GO:0006810| transport GABRA1;GABRR1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP1A1;CYP2C8 GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2C8 GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0043200| response to amino acid stimulus GLRA3;LYN GO:0014070| response to organic cyclic compound LYN;CYP1A1 GO:0009636| response to toxin CYP1A1;LYN GO:0008283| cell proliferation CYP1A1;GLUL;SRC GO:0010033| response to organic substance CYP1A1;CDK2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 7041:[DB06616 DB01078] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01078|Deslanoside ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;MAP3K2 GO:0042493| response to drug ABCB1;SRC;ATP1A1;LYN GO:0006813| potassium ion transport CDK2;ATP1A1 7042:[DB06616 DB09139] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB09139|Technetium Tc-99m oxidronate ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0002576| platelet degranulation ALB;LYN 7043:[DB06616 DB11945] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11945|Avelumab CD274 common genes common pathways GO:0030335| positive regulation of cell migration CD274;LYN GO:0031295| T cell costimulation LYN;CD274;SRC GO:0007165| signal transduction MAP2K1;SRC;BCR;LYN;CD274 7044:[DB06616 DB01786] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01786|D-Alanine SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 7045:[DB06616 DB04451] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways GO:2000249| regulation of actin cytoskeleton reorganization CTSV;ABL1 GO:0014070| response to organic cyclic compound LYN;CTSV 7046:[DB06616 DB02101] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02101|(S,R)-fidarestat AKR1B1 common genes common pathways GO:0010033| response to organic substance CDK2;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;HCK;SRC GO:0055114| oxidation-reduction process CYP2C8;AKR1B1;CYP3A4 7047:[DB06616 DB06258] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06258|Bimoclomol HSF1 common genes common pathways GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;HSF1 GO:0070301| cellular response to hydrogen peroxide ABL1;HSF1 GO:0010628| positive regulation of gene expression HSF1;SRC;MAP2K1 GO:0014070| response to organic cyclic compound HSF1;LYN GO:0043200| response to amino acid stimulus LYN;HSF1 GO:1900034| HSF1;CAMK2G GO:0006468| protein phosphorylation ABL1;HSF1;SRC;BCR;MAP2K2;HCK;MAP2K1;CAMK2G;CDK2;LYN;MAP3K2 GO:0034605| cellular response to heat HSF1;LYN GO:0000165| MAPKKK cascade CAMK2G;HSF1;MAP2K1;MAP2K2 GO:0006355| regulation of transcription, DNA-dependent HSF1;ABL1 GO:0010629| negative regulation of gene expression HSF1;MAP2K1;MAP2K2 GO:0006974| response to DNA damage stimulus HSF1;ABL1;CDK2;LYN GO:0006281| DNA repair ABL1;HSF1;CDK2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HSF1;CDK2 GO:0071222| cellular response to lipopolysaccharide ABL1;HSF1;BCR;SRC GO:1904528| HSF1;ABL1 GO:0008284| positive regulation of cell proliferation HCK;HSF1;CDK2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein HSF1;LYN GO:0032496| response to lipopolysaccharide HSF1;BCR GO:0045931| positive regulation of mitotic cell cycle HSF1;ABL1 7048:[DB06616 DB01260] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01260|Desonide NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction NR3C1;LYN;MAP2K1;BCR;SRC GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0002933| CYP2C8;CYP3A4 GO:0006915| apoptotic process ABL1;NR3C1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0007049| cell cycle NR3C1;CDK2;SRC GO:0009822| alkaloid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;SRC GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;NR3C1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ABL1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0051301| cell division NR3C1;CDK2 7049:[DB06616 DB05624] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05624|Teverelix GNRHR common genes common pathways GO:0007275| multicellular organismal development CDK2;CAMK2G;GNRHR GO:0007165| signal transduction LYN;MAP2K1;BCR;SRC;GNRHR 7050:[DB06616 DB02929] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02929|K201 ANXA5 common genes common pathways GO:0007165| signal transduction ANXA5;LYN;SRC;BCR;MAP2K1 GO:0007596| blood coagulation LYN;ANXA5 GO:0010033| response to organic substance CDK2;ANXA5 GO:0002576| platelet degranulation LYN;ANXA5 GO:0043066| negative regulation of apoptotic process SRC;HCK;ANXA5 7051:[DB06616 DB04020] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways GO:0030520| intracellular estrogen receptor signaling pathway ESR2;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;SRC;MAP2K2;MAP2K1;CDK2;MAP3K2 GO:0007165| signal transduction SRC;BCR;MAP2K1;ESR2;LYN 7052:[DB06616 DB07256] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07256|3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE EPHB4 common genes common pathways GO:0007275| multicellular organismal development CDK2;EPHB4;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation EPHB4;LYN;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0007155| cell adhesion EPHB4;SRC;HCK;ABL1 GO:0048013| ephrin receptor signaling pathway LYN;EPHB4;SRC GO:0046777| protein autophosphorylation CAMK2G;EPHB4;LYN;SRC;BCR;HCK;ABL1 GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;EPHB4;CDK2;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EPHB4;LYN;HCK GO:0016310| phosphorylation CAMK2G;EPHB4;CDK2;LYN;MAP3K2;ABL1;SRC;MAP2K2;BCR;HCK;MAP2K1 7053:[DB06616 DB05119] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05119|Rilapladib PLA2G7 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G7 7054:[DB06616 DB11770] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11770|Talinolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP3A4 7055:[DB06616 DB07723] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways GO:0014070| response to organic cyclic compound LYN;PPARG GO:0010033| response to organic substance PPARG;CDK2 GO:0008285| negative regulation of cell proliferation MAP2K1;LYN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0032869| cellular response to insulin stimulus PPARG;SRC GO:0007165| signal transduction BCR;SRC;MAP2K1;PPARG;LYN GO:0042493| response to drug PPARG;LYN;ABCB1;SRC GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG;MAP3K2;MAP2K1;MAP2K2;SRC GO:0007507| heart development MAP2K1;PPARG GO:0045087| innate immune response PPARG;LYN;SRC;HCK;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009612| response to mechanical stimulus SRC;PPARG 7056:[DB06616 DB08038] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 7057:[DB06616 DB04711] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04711|Iodipamide ALB common genes common pathways GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC 7058:[DB06616 DB03510] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways GO:0002376| immune system process LYN;ADSSL1;SRC;HCK 7059:[DB06616 DB01065] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0010628| positive regulation of gene expression MAP2K1;SRC;CALR GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0030336| negative regulation of cell migration CYP1B1;BCR GO:0071902| positive regulation of protein serine/threonine kinase activity MAP2K2;SRC;MAP2K1;CALM1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0010033| response to organic substance CYP1A2;CALR;CYP1A1;CDK2 GO:0008285| negative regulation of cell proliferation LYN;MAP2K1;CYP1B1 GO:0050766| positive regulation of phagocytosis CALR;BCR GO:0045892| negative regulation of transcription, DNA-dependent CALR;SRC;RORB GO:0070301| cellular response to hydrogen peroxide CYP1B1;ABL1 GO:0002933| CYP1A1;CYP3A4;CYP2C8 GO:0009636| response to toxin CYP1B1;CYP1A1;LYN;SLC22A8 GO:0014070| response to organic cyclic compound CYP1A2;LYN;CYP1A1 GO:0008283| cell proliferation CYP1A1;SRC GO:0038095| CALM1;LYN GO:0055085| transmembrane transport ABCB1;CALM1;SLC22A8 GO:1900026| ABL1;CALR GO:0006979| response to oxidative stress MPO;ABL1;EPX GO:0002376| immune system process LYN;IDO1;HCK;SRC GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4;CYP1A1;CYP2C9;CYP1A2 GO:0097267| CYP2C8;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0007165| signal transduction BCR;SRC;MAP2K1;MTNR1A;MTNR1B;ESR1;LYN GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP1B1;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0010595| positive regulation of endothelial cell migration CALR;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1 GO:0090398| cellular senescence CALR;MAP2K1 GO:0006954| inflammatory response IDO1;HCK;LYN GO:0000165| MAPKKK cascade CAMK2G;MAP2K1;MAP2K2;CALM1 GO:0031954| positive regulation of protein autophosphorylation SRC;CALM1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;SRC;MAP2K1;RORB;MAP3K2;ESR1;CDK2 GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;ESR1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0042493| response to drug ABCB1;SRC;CALR;CYP1A1;LYN;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent RORB;ABL1;ESR1;CALR GO:0055114| oxidation-reduction process MPO;CYP1B1;IDO1;CYP2C19;CYP2C8;CYP1A2;EPX;NQO2;CYP3A4;CYP19A1;CYP2C9;CYP1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0071300| cellular response to retinoic acid LYN;RORB GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1A2;CYP2C19;CYP2C8;CYP1B1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP3A4;CYP1A2;NQO2 GO:0060065| uterus development ESR1;CYP19A1;SRC GO:0043066| negative regulation of apoptotic process HCK;MPO;SRC GO:0009612| response to mechanical stimulus MPO;SRC GO:0050727| regulation of inflammatory response HCK;ESR1;LYN GO:0002576| platelet degranulation CALM1;LYN GO:0043065| positive regulation of apoptotic process ABL1;IDO1;SRC;CYP1B1 GO:0009615| response to virus SRC;CYP1A1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;CALR GO:0006629| lipid metabolic process CYP1A2;CYP2C9;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0007155| cell adhesion HCK;SRC;CYP1B1;ABL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1;CDK2 GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;ESR1;CALR GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2C9;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;MPO;BCR;IDO1 GO:0007275| multicellular organismal development RORB;CAMK2G;CDK2 GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP1A2 7060:[DB06616 DB04830] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04830|Buformin SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0055085| transmembrane transport ABCB1;SLC22A1 7061:[DB06616 DB04664] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2B6;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2B6 GO:0042738| exogenous drug catabolic process CYP2B6;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4;CYP2C8 7062:[DB06616 DB01535] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ABL1 GO:0007165| signal transduction OPRK1;BCR;SRC;MAP2K1;LYN;OPRM1;OPRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ABL1;MAP2K2;SRC;MAP2K1 GO:0032868| response to insulin stimulus LYN;OPRK1 GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;LYN GO:0032496| response to lipopolysaccharide OPRM1;BCR GO:0071222| cellular response to lipopolysaccharide ABL1;OPRK1;BCR;SRC GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;OPRD1 GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G 7063:[DB06616 DB04534] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04534|5-Nitroindazole NOS2;NOS3 common genes common pathways GO:0032496| response to lipopolysaccharide NOS2;BCR GO:0042127| regulation of cell proliferation SRC;ABL1;NOS2 GO:0043542| endothelial cell migration NOS3;ABL1 GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;NOS2 GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;NOS3;LYN GO:0010629| negative regulation of gene expression MAP2K1;MAP2K2;NOS2 GO:0055114| oxidation-reduction process NOS3;CYP2C8;NOS2;CYP3A4 GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;LYN 7064:[DB06616 DB00679] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes CYP2C8 common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;LYN;ABL1;SRC GO:0016032| viral reproduction SRC;HCK;HTR2A;LYN GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0023014| signal transduction via phosphorylation event LYN;KCNH2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19 GO:0042493| response to drug DRD1;ABCB1;DRD2;SRC;ADRA1A;CYP2E1;HTR2A;LYN GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006082| organic acid metabolic process CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8;CYP2C19 GO:0035556| intracellular signal transduction LYN;CAMK2G;ADRA1A;SRC;DRD2;BCR;ADRA1B GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0008284| positive regulation of cell proliferation LYN;CDK2;HTR2A;HCK GO:0007275| multicellular organismal development ADRA1B;CAMK2G;CDK2 GO:0048678| response to axon injury DRD2;LYN GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0001932| regulation of protein phosphorylation LYN;MAP2K1;DRD1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0008285| negative regulation of cell proliferation LYN;ADRA1A;DRD2;MAP2K1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression MAP2K1;SRC;DRD1 GO:0030336| negative regulation of cell migration DRD2;BCR GO:0006915| apoptotic process ADRA1A;ABL1 GO:0055085| transmembrane transport KCNH2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;MAP2K1;MAP2K2;DRD2;SRC;ADRA1A;HTR2A GO:0002933| CYP2C8;CYP3A4 GO:0009636| response to toxin LYN;DRD2 GO:0008283| cell proliferation SRC;ADRA1B GO:0030900| forebrain development SRC;DRD2 GO:1903351| ABL1;DRD1 GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;DRD1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0097267| CYP2C19;CYP2C8 GO:0007165| signal transduction HTR2A;LYN;BCR;ADRA1A;DRD2;SRC;MAP2K1;ADRA1B;DRD1 GO:0009725| response to hormone stimulus LYN;ADRA1A GO:0006813| potassium ion transport CDK2;KCNH2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ABL1;ADRA1B;ADRA1A GO:0030335| positive regulation of cell migration LYN;DRD1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6 7065:[DB06616 DB08480] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08480|4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0042493| response to drug SRC;ABCB1;MAOB;LYN GO:0055114| oxidation-reduction process MAOB;CYP3A4;CYP2C8 GO:0009636| response to toxin LYN;MAOB 7066:[DB06616 DB06897] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways GO:0016310| phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;PLK1;ABL1;MAP3K2;LYN;CDK2;CAMK2G GO:0006468| protein phosphorylation ABL1;PLK1;MAP2K1;HCK;MAP2K2;BCR;SRC;CDK2;LYN;CAMK2G;MAP3K2 GO:0051439| regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle PLK1;CDK2 GO:0031648| protein destabilization SRC;PLK1 GO:1900182| PLK1;SRC GO:0008283| cell proliferation SRC;PLK1 GO:0045184| establishment of protein localization ABL1;PLK1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1;CDK2 GO:0007049| cell cycle CDK2;PLK1;SRC GO:0043393| regulation of protein binding PLK1;SRC GO:0051726| regulation of cell cycle PLK1;ABL1;BCR;SRC GO:0018105| peptidyl-serine phosphorylation SRC;PLK1;CAMK2G;CDK2 GO:0043066| negative regulation of apoptotic process PLK1;SRC;HCK GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;CDK2 GO:0007346| regulation of mitotic cell cycle MAP2K1;MAP2K2;PLK1;MAP3K2 GO:0000278| mitotic cell cycle PLK1;ABL1 GO:0051301| cell division PLK1;CDK2 GO:0010389| regulation of G2/M transition of mitotic cell cycle CDK2;PLK1 7067:[DB06616 DB05150] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05150|CAD106 APP common genes common pathways GO:0006979| response to oxidative stress APP;ABL1 GO:0030900| forebrain development SRC;APP GO:0006468| protein phosphorylation ABL1;BCR;MAP2K2;SRC;MAP2K1;HCK;CAMK2G;LYN;CDK2;APP;MAP3K2 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;APP GO:1900272| APP;ABL1 GO:0010628| positive regulation of gene expression SRC;MAP2K1;APP GO:0008285| negative regulation of cell proliferation MAP2K1;APP;LYN GO:0031175| neuron projection development LYN;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K2;SRC;MAP2K1;ABL1;APP GO:0006915| apoptotic process ABL1;APP GO:0000187| activation of MAPK activity MAP2K1;MAP2K2;MAP3K2;APP GO:0002576| platelet degranulation LYN;APP GO:0043065| positive regulation of apoptotic process APP;ABL1;SRC GO:0006897| endocytosis APP;ABL1 GO:0042327| positive regulation of phosphorylation APP;LYN GO:0007155| cell adhesion SRC;HCK;ABL1;APP GO:0045087| innate immune response SRC;HCK;ABL1;APP;LYN GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;APP GO:0007399| nervous system development APP;CAMK2G GO:0045931| positive regulation of mitotic cell cycle ABL1;APP GO:0043393| regulation of protein binding APP;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;LYN;SRC;ABL1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;APP GO:0010629| negative regulation of gene expression MAP2K2;MAP2K1;APP GO:1901216| APP;ABL1 GO:0050885| neuromuscular process controlling balance BCR;ABL1;APP GO:0001934| positive regulation of protein phosphorylation APP;LYN;ABL1 7068:[DB06616 DB01381] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade MAP2K1;MAP2K2;SRC;PLA2G2A;ABL1 GO:0009791| post-embryonic development ABL1;GABRG2 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006810| transport ABCB1;GABRB2;GABRA1;GABRG2;SLC6A2 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0042493| response to drug ABCB1;SRC;LYN;SLC6A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PLA2G2A 7069:[DB06616 DB01208] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes ABCB1 common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide ABCC2;BCR;CYP1A2 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0071222| cellular response to lipopolysaccharide BCR;SRC;ABCC2;ABL1 GO:0043065| positive regulation of apoptotic process TOP2A;SRC;ABL1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006974| response to DNA damage stimulus CDK2;LYN;TOP2A;ABL1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;LYN;SRC;ABCB1;ABCC2 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1;ABCC2 GO:0042908| xenobiotic transport ABCB1 GO:0006979| response to oxidative stress ABCC2;ABL1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0055085| transmembrane transport ABCB1;ABCC2;SLC22A5 GO:0000086| G2/M transition of mitotic cell cycle CDK2;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCC2;ABCB1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CYP1A2;CDK2 7070:[DB06616 DB01686] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01686|N,N-dimethylarginine NOS2;NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;MAP2K1;LYN GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4;NOS2 GO:0010629| negative regulation of gene expression NOS2;MAP2K2;MAP2K1 GO:0071222| cellular response to lipopolysaccharide NOS2;SRC;BCR;ABL1 GO:0031663| lipopolysaccharide-mediated signaling pathway LYN;HCK;NOS3 GO:0043542| endothelial cell migration NOS3;ABL1 GO:0042127| regulation of cell proliferation NOS2;SRC;ABL1 GO:0032496| response to lipopolysaccharide NOS2;BCR 7071:[DB06616 DB08620] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08620|{(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide CHRFAM7A common genes common pathways GO:0007165| signal transduction LYN;CHRFAM7A;MAP2K1;BCR;SRC 7072:[DB06616 DB13083] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB13083|Talarozole CYP26A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP26A1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP26A1;CYP3A4;CYP2C8 7073:[DB06616 DB04287] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04287|(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade PLA2G2A;ABL1;MAP2K1;MAP2K2;SRC 7074:[DB06616 DB01283] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0034605| cellular response to heat PTGS2;LYN GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP1A2;CYP2C8;CYP2C19 GO:0070542| response to fatty acid SRC;PTGS2 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP1A2;UGT1A9;CYP2C19;CYP2C8 GO:0097267| CYP2C19;CYP2C8;CYP1A2;CYP2C9 GO:0006979| response to oxidative stress PTGS2;PTGS1;ABL1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4;CYP2C9 GO:0014070| response to organic cyclic compound LYN;CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;CDK2 GO:0008285| negative regulation of cell proliferation PTGS2;LYN;MAP2K1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP1A2;CYP3A4;CYP2C9 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2;BCR GO:0042127| regulation of cell proliferation PTGS2;ABL1;PTGS1;SRC GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP1A2 GO:0071260| cellular response to mechanical stimulus MAP3K2;PTGS2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2;CYP1A2;PTGS1 GO:0043066| negative regulation of apoptotic process SRC;HCK;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;PTGS1;CYP2C9;CYP3A4;CYP1A2;UGT1A9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP1A2;CYP2C9 GO:0008284| positive regulation of cell proliferation HCK;CDK2;LYN;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;ABL1;PTGS2 GO:0050727| regulation of inflammatory response HCK;LYN;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP2C9;CYP3A4;PTGS1;CYP2C8;CYP2C19 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042493| response to drug SRC;ABCB1;LYN;CYP1A2;PTGS2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response HCK;PTGS1;PTGS2;LYN 7075:[DB06616 DB08354] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08354|2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation LYN;CDK2;CSNK2A1;HCK GO:1901796| CDK2;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CSNK2A1 GO:0016236| macroautophagy CSNK2A1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;CSNK2A1 GO:0007165| signal transduction LYN;CSNK2A1;SRC;BCR;MAP2K1 GO:0016310| phosphorylation MAP3K2;CSNK2A1;CAMK2G;LYN;CDK2;SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1 GO:0006468| protein phosphorylation CSNK2A1;MAP3K2;CDK2;LYN;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0007049| cell cycle SRC;CSNK2A1;CDK2 GO:0006915| apoptotic process CSNK2A1;ABL1 GO:0018107| peptidyl-threonine phosphorylation MAP2K1;CAMK2G;CSNK2A1 7076:[DB06616 DB00403] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00403|Ceruletide CCKAR common genes common pathways GO:0030900| forebrain development SRC;CCKAR GO:0007165| signal transduction CCKAR;LYN;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CCKAR 7077:[DB06616 DB04150] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04150|Threonine Derivative PAM common genes common pathways GO:0032956| regulation of actin cytoskeleton organization ABL1;PAM GO:0007417| central nervous system development LYN;PAM;SRC GO:0042493| response to drug PAM;LYN;ABCB1;SRC GO:0055114| oxidation-reduction process PAM;CYP3A4;CYP2C8 GO:0007507| heart development MAP2K1;PAM 7078:[DB06616 DB04716] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways GO:0007498| mesoderm development HCK;JAK2 GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein JAK2;LYN GO:0018108| peptidyl-tyrosine phosphorylation JAK3;LYN;JAK2;ABL1;SRC;BCR;MAP2K2;HCK;MAP2K1 GO:0042127| regulation of cell proliferation JAK2;JAK1;SRC;TYK2;ABL1 GO:0032496| response to lipopolysaccharide BCR;JAK2 GO:0048008| platelet-derived growth factor receptor signaling pathway JAK2;ABL1;BCR;SRC GO:0008360| regulation of cell shape HCK;DAPK3 GO:0045597| positive regulation of cell differentiation JAK2;MAP2K1 GO:0045087| innate immune response JAK2;LYN;JAK3;JAK1;HCK;SRC;TYK2;ABL1 GO:0042981| regulation of apoptotic process MAP3K2;JAK2;JAK3;MAP2K1;MAP2K2;DAPK3 GO:0043065| positive regulation of apoptotic process SRC;DAPK3;ABL1;JAK2 GO:0050727| regulation of inflammatory response HCK;LYN;JAK2 GO:0008284| positive regulation of cell proliferation CDK2;LYN;JAK2;HCK GO:0018105| peptidyl-serine phosphorylation CAMK2G;CDK2;SRC;DAPK3 GO:0035556| intracellular signal transduction DAPK3;TYK2;BCR;SRC;JAK1;CAMK2G;LYN;JAK3;JAK2 GO:2000145| regulation of cell motility DAPK3;ABL1 GO:2000249| regulation of actin cytoskeleton reorganization ABL1;DAPK3 GO:0007346| regulation of mitotic cell cycle MAP2K2;MAP2K1;DAPK3;MAP3K2 GO:0038083| HCK;JAK1;SRC;TYK2;ABL1;JAK2;JAK3;LYN GO:0006355| regulation of transcription, DNA-dependent DAPK3;ABL1 GO:0010506| regulation of autophagy DAPK3;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;JAK2;ABL1;SRC GO:0019221| cytokine-mediated signaling pathway JAK2;HCK GO:0000165| MAPKKK cascade JAK3;CAMK2G;JAK2;JAK1;MAP2K1;MAP2K2 GO:0002250| adaptive immune response JAK3;LYN;JAK2 GO:0030218| erythrocyte differentiation JAK3;LYN;JAK2 GO:0006954| inflammatory response LYN;JAK3;HCK GO:0030154| cell differentiation JAK1;HCK;TYK2;JAK2;CAMK2G GO:0006468| protein phosphorylation MAP3K2;JAK2;LYN;CDK2;JAK3;CAMK2G;MAP2K1;HCK;JAK1;MAP2K2;BCR;SRC;TYK2;ABL1;DAPK3 GO:0007204| elevation of cytosolic calcium ion concentration JAK2;ABL1 GO:0000186| activation of MAPKK activity JAK2;MAP3K2 GO:0016310| phosphorylation TYK2;ABL1;DAPK3;HCK;JAK1;MAP2K1;SRC;MAP2K2;BCR;JAK3;LYN;CDK2;CAMK2G;MAP3K2;JAK2 GO:0030335| positive regulation of cell migration LYN;JAK2;DAPK3 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;JAK1;HCK;TYK2 GO:0007165| signal transduction LYN;JAK2;MAP2K1;SRC;BCR GO:0065009| regulation of molecular function JAK1;JAK3;CAMK2G GO:0002376| immune system process SRC;HCK;JAK2;LYN;JAK3 GO:0022408| negative regulation of cell-cell adhesion JAK2;ABL1 GO:0060333| interferon-gamma-mediated signaling pathway HCK;JAK1;CAMK2G;JAK2 GO:0006979| response to oxidative stress JAK2;ABL1 GO:0018107| peptidyl-threonine phosphorylation DAPK3;MAP2K1;CAMK2G GO:0006915| apoptotic process DAPK3;ABL1;JAK2 GO:0007596| blood coagulation JAK2;LYN GO:0060397| JAK-STAT cascade involved in growth hormone signaling pathway JAK3;LYN;JAK2 GO:0030182| neuron differentiation DAPK3;ABL1;MAP2K1 GO:0016477| cell migration SRC;JAK1;TYK2;JAK2;JAK3 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway DAPK3;SRC GO:0008285| negative regulation of cell proliferation JAK2;LYN;MAP2K1 GO:0046777| protein autophosphorylation ABL1;DAPK3;BCR;SRC;HCK;JAK1;CAMK2G;LYN;JAK2 GO:0006928| cellular component movement MAP2K1;JAK2 7079:[DB06616 DB06835] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 7080:[DB06616 DB01003] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNMA1 GO:0010033| response to organic substance S100P;CDK2 GO:0006813| potassium ion transport KCNMA1;CDK2 GO:0043542| endothelial cell migration ABL1;S100P GO:0043065| positive regulation of apoptotic process ABL1;SRC;KCNMA1 7081:[DB06616 DB05311] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05311|Ecallantide KLKB1 common genes common pathways GO:0006954| inflammatory response KLKB1;LYN;HCK GO:0007596| blood coagulation LYN;KLKB1 7082:[DB06616 DB11597] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 7083:[DB06616 DB07033] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways GO:0051281| positive regulation of release of sequestered calcium ion into cytosol ABL1;PDPK1 GO:0031295| T cell costimulation SRC;LYN;PDPK1 GO:0016310| phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;PDPK1;LYN;CDK2 GO:0006468| protein phosphorylation BCR;MAP2K2;SRC;MAP2K1;HCK;ABL1;MAP3K2;CAMK2G;LYN;CDK2;PDPK1 GO:0032869| cellular response to insulin stimulus SRC;PDPK1 GO:0030168| platelet activation LYN;PDPK1;SRC GO:0046777| protein autophosphorylation LYN;PDPK1;CAMK2G;ABL1;HCK;BCR;SRC GO:0038095| PDPK1;LYN GO:0016477| cell migration PDPK1;SRC GO:0018107| peptidyl-threonine phosphorylation MAP2K1;PDPK1;CAMK2G GO:0043304| regulation of mast cell degranulation PDPK1;LYN GO:0018105| peptidyl-serine phosphorylation SRC;PDPK1;CDK2;CAMK2G GO:0035556| intracellular signal transduction BCR;SRC;LYN;PDPK1;CAMK2G GO:0032148| activation of protein kinase B activity PDPK1;SRC GO:0002223| stimulatory C-type lectin receptor signaling pathway PDPK1;LYN;SRC GO:0030036| actin cytoskeleton organization PDPK1;BCR;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PDPK1 GO:0007173| epidermal growth factor receptor signaling pathway SRC;ABL1;PDPK1 7084:[DB06616 DB06902] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06902|4-(1-methyl-1-phenylethyl)phenol ESRRG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;ESRRG GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;MAP2K2;SRC;MAP2K1;ESRRG 7085:[DB06616 DB00551] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00551|Acetohydroxamic acid ureC;MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;CDK2 GO:0010628| positive regulation of gene expression MAP2K1;SRC;MMP12 7086:[DB06616 DB11740] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11740|MK-1775 WEE1 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation WEE1;LYN;ABL1;HCK;MAP2K1;SRC;MAP2K2;BCR GO:0051726| regulation of cell cycle ABL1;SRC;BCR;WEE1 GO:0000278| mitotic cell cycle ABL1;WEE1 GO:0051301| cell division WEE1;CDK2 GO:0000082| G1/S transition of mitotic cell cycle WEE1;CDK2;CAMK2G GO:0016310| phosphorylation MAP3K2;CDK2;LYN;WEE1;CAMK2G;HCK;MAP2K1;SRC;BCR;MAP2K2;ABL1 GO:0006468| protein phosphorylation WEE1;CDK2;LYN;CAMK2G;MAP3K2;ABL1;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0000086| G2/M transition of mitotic cell cycle WEE1;CDK2;ABCB1 GO:0007049| cell cycle SRC;CDK2;WEE1 7087:[DB06616 DB03408] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03408|gamma-Glutamylcysteine GSS common genes common pathways GO:0043200| response to amino acid stimulus GSS;LYN GO:0006979| response to oxidative stress GSS;ABL1 GO:0031667| response to nutrient levels GSS;SRC GO:0007399| nervous system development CAMK2G;GSS 7088:[DB06616 DB04209] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04209|Dequalinium XIAP;CNGA1;KCNMA1 common genes common pathways GO:0006915| apoptotic process XIAP;ABL1 GO:0055085| transmembrane transport KCNMA1;CNGA1;ABCB1 GO:0090263| positive regulation of canonical Wnt receptor signaling pathway SRC;XIAP GO:0006810| transport ABCB1;CNGA1 GO:0007165| signal transduction CNGA1;SRC;BCR;MAP2K1;LYN GO:0006813| potassium ion transport KCNMA1;CDK2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;XIAP GO:0042127| regulation of cell proliferation XIAP;SRC;ABL1 GO:0006974| response to DNA damage stimulus XIAP;LYN;CDK2;ABL1 GO:0043066| negative regulation of apoptotic process SRC;HCK;XIAP GO:0050727| regulation of inflammatory response LYN;XIAP;HCK GO:0043065| positive regulation of apoptotic process ABL1;SRC;KCNMA1 7089:[DB06616 DB01830] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways GO:0045087| innate immune response SRC;LCK;HCK;ABL1;LYN GO:0018108| peptidyl-tyrosine phosphorylation HCK;MAP2K1;LCK;SRC;MAP2K2;BCR;ABL1;LYN GO:0042127| regulation of cell proliferation ABL1;LCK;SRC GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC GO:0016032| viral reproduction LYN;HCK;LCK;SRC GO:0050900| leukocyte migration LCK;SRC;LYN GO:0038083| SRC;LCK;HCK;ABL1;LYN GO:0042493| response to drug ABCB1;SRC;LCK;LYN GO:0030097| hemopoiesis LCK;LYN GO:0006468| protein phosphorylation ABL1;MAP2K1;LCK;HCK;MAP2K2;BCR;SRC;LYN;CDK2;CAMK2G;MAP3K2 GO:0030168| platelet activation LYN;SRC;LCK GO:0016310| phosphorylation CDK2;LYN;CAMK2G;MAP3K2;ABL1;LCK;MAP2K1;HCK;BCR;MAP2K2;SRC GO:0031295| T cell costimulation SRC;LCK;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LYN;LCK;HCK GO:0050853| B cell receptor signaling pathway ABL1;LCK;LYN GO:0050690| regulation of defense response to virus by virus LCK;HCK GO:0016477| cell migration LCK;SRC GO:0006470| protein dephosphorylation LCK;CAMK2G 7090:[DB06616 DB08933] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19 GO:0097267| CYP2C8;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 7091:[DB06616 DB05465] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;FLT3;PDGFD GO:0070301| cellular response to hydrogen peroxide ABL1;PDGFD GO:0097028| dendritic cell differentiation LYN;FLT3 GO:0046777| protein autophosphorylation ABL1;BCR;SRC;HCK;CAMK2G;LYN;FLT3 GO:0070374| positive regulation of ERK1 and ERK2 cascade PDGFD;MAP2K2;SRC;MAP2K1;ABL1 GO:0007596| blood coagulation LYN;PDGFD GO:0030097| hemopoiesis LYN;FLT3 GO:0006468| protein phosphorylation SRC;BCR;MAP2K2;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;FLT3;CDK2;LYN GO:0030154| cell differentiation HCK;CAMK2G;FLT3 GO:0036120| SRC;PDGFD GO:0016310| phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;MAP3K2;CAMK2G;FLT3;CDK2;LYN GO:0043552| positive regulation of phosphatidylinositol 3-kinase activity SRC;LYN;FLT3 GO:0030335| positive regulation of cell migration LYN;PDGFD GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT3;LYN;HCK GO:0019221| cytokine-mediated signaling pathway HCK;FLT3 GO:0031954| positive regulation of protein autophosphorylation PDGFD;SRC GO:0042981| regulation of apoptotic process MAP2K1;MAP2K2;MAP3K2;FLT3 GO:0008284| positive regulation of cell proliferation LYN;CDK2;FLT3;PDGFD;HCK GO:0071560| cellular response to transforming growth factor beta stimulus SRC;PDGFD GO:0007275| multicellular organismal development CDK2;PDGFD;CAMK2G GO:0018108| peptidyl-tyrosine phosphorylation SRC;MAP2K2;BCR;HCK;MAP2K1;ABL1;FLT3;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein FLT3;LYN GO:0048008| platelet-derived growth factor receptor signaling pathway ABL1;BCR;SRC;PDGFD 7092:[DB06616 DB11632] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes CYP2C8 common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0032496| response to lipopolysaccharide COMT;BCR GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2C19 GO:0006082| organic acid metabolic process CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0042493| response to drug SRC;ABCB1;COMT;LYN GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0097267| CYP2C8;CYP2C19 GO:0002933| CYP2C8;CYP3A4 GO:0014070| response to organic cyclic compound COMT;LYN 7093:[DB06616 DB02398] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02398|6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0006935| chemotaxis PLAU;MAP2K1 GO:0042127| regulation of cell proliferation PLAU;ABL1;SRC GO:0033628| regulation of cell adhesion mediated by integrin PLAU;LYN GO:0007596| blood coagulation LYN;PLAU GO:0007165| signal transduction LYN;PLAU;MAP2K1;SRC;BCR GO:0030335| positive regulation of cell migration LYN;PLAU 7094:[DB06616 DB00181] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways GO:0007165| signal transduction GABBR1;LYN;SRC;BCR;MAP2K1;GABBR2 GO:0055085| transmembrane transport ABCB1;SLC22A8 GO:0009636| response to toxin SLC22A8;LYN 7095:[DB06616 DB02676] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways GO:0050900| leukocyte migration SRC;PDE4D;LYN GO:0071222| cellular response to lipopolysaccharide ABL1;BCR;SRC;PDE4D GO:0007165| signal transduction MAP2K1;BCR;SRC;LYN;PDE4D 7096:[DB06616 DB02555] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB02555|SP4160 IL2 common genes common pathways GO:0065009| regulation of molecular function CAMK2G;IL2 GO:0002376| immune system process HCK;SRC;IL2;LYN GO:0007204| elevation of cytosolic calcium ion concentration IL2;ABL1 GO:0007155| cell adhesion HCK;SRC;IL2;ABL1 GO:0043066| negative regulation of apoptotic process SRC;HCK;IL2 GO:0008284| positive regulation of cell proliferation HCK;IL2;CDK2;LYN GO:0042531| positive regulation of tyrosine phosphorylation of STAT protein IL2;LYN GO:0001933| negative regulation of protein phosphorylation IL2;LYN GO:0000165| MAPKKK cascade IL2;MAP2K1;MAP2K2;CAMK2G GO:0002250| adaptive immune response LYN;IL2 GO:0050728| negative regulation of inflammatory response BCR;IL2 GO:0001934| positive regulation of protein phosphorylation IL2;ABL1;LYN 7097:[DB06616 DB08891] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways GO:0007165| signal transduction LYN;GABBR1;GABBR2;SRC;BCR;MAP2K1 7098:[DB06616 DB08618] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08618|3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER IGHG2 common genes common pathways GO:0038096| ABL1;SRC;HCK;LYN;IGHG2 GO:0002250| adaptive immune response IGHG2;LYN GO:0045087| innate immune response HCK;SRC;ABL1;IGHG2;LYN GO:0050853| B cell receptor signaling pathway ABL1;IGHG2;LYN GO:0002376| immune system process SRC;HCK;LYN;IGHG2 7099:[DB06616 DB11674] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB11674|Equol ESR2;SHBG common genes common pathways GO:0007165| signal transduction LYN;ESR2;BCR;SRC;MAP2K1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;CDK2 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;MAP3K2;ESR2;SRC;MAP2K2;MAP2K1 GO:0006355| regulation of transcription, DNA-dependent ESR2;ABL1 7100:[DB06616 DB01884] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways GO:0043542| endothelial cell migration DPP4;ABL1 GO:0008284| positive regulation of cell proliferation HCK;LYN;CDK2;DPP4 GO:0007155| cell adhesion ABL1;HCK;SRC;DPP4 GO:0031295| T cell costimulation DPP4;LYN;SRC 7101:[DB06616 DB07913] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB07913|HOMOPHENYLALANINYLMETHANE CTSF common genes common pathways 7102:[DB06616 DB04677] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04677|N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;BCR GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOB GO:0042493| response to drug LYN;MAOB;ABCB1;SRC GO:0009636| response to toxin MAOB;LYN 7103:[DB06616 DB01060] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01060|Amoxicillin CYP2C19;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8 GO:0097267| CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC15A1;SLC15A2 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19 7104:[DB06616 DB06160] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;SRC;LYN;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;BCR GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound LYN;CYP1A2 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0010033| response to organic substance CDK2;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A2 7105:[DB06616 DB04079] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB04079|Heptane-1,2,3-Triol RHO common genes common pathways GO:0007165| signal transduction MAP2K1;BCR;SRC;RHO;LYN GO:0006468| protein phosphorylation MAP3K2;RHO;CDK2;LYN;CAMK2G;MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1 7106:[DB06616 DB03087] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03087|2-(Sec-Butyl)Thiazole LCN9 common genes common pathways 7107:[DB06616 DB08855] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB08855|Leukotriene C4 CYSLTR1;CYSLTR2;ABCC1;SLCO1B1;SLCO1B3 common genes common pathways GO:0007165| signal transduction LYN;CYSLTR2;MAP2K1;SRC;CYSLTR1;BCR GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;CYSLTR1 GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1B1;ABCC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CYSLTR2;SRC;MAP2K2;MAP2K1;ABL1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006935| chemotaxis CYSLTR1;MAP2K1 GO:0006816| calcium ion transport CAMK2G;CYSLTR1 GO:0042493| response to drug ABCC1;LYN;ABCB1;SRC 7108:[DB06616 DB03881] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03881|MT-Immucillin-H PNP common genes common pathways GO:0042493| response to drug ABCB1;SRC;LYN;PNP 7109:[DB06616 DB01276] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01276|Exenatide GLP1R;ALB common genes common pathways GO:0007165| signal transduction GLP1R;LYN;MAP2K1;BCR;SRC GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;ABL1 GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process SRC;HCK;ALB 7110:[DB06616 DB14040] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB14040|Eptinezumab CALCA;CALCB common genes common pathways GO:0007165| signal transduction CALCB;MAP2K1;SRC;BCR;LYN GO:0006468| protein phosphorylation MAP2K1;HCK;BCR;MAP2K2;SRC;ABL1;MAP3K2;CALCA;LYN;CDK2;CAMK2G GO:0045087| innate immune response HCK;SRC;ABL1;LYN;CALCA GO:0043542| endothelial cell migration ABL1;CALCA 7111:[DB06616 DB01949] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways GO:0030335| positive regulation of cell migration LYN;MMP9 GO:0048013| ephrin receptor signaling pathway SRC;LYN;MMP9 GO:0034614| cellular response to reactive oxygen species MMP9;SRC GO:0043065| positive regulation of apoptotic process MMP9;ABL1;SRC GO:0043066| negative regulation of apoptotic process SRC;HCK;MMP9 GO:0050900| leukocyte migration SRC;MMP9;LYN GO:0001934| positive regulation of protein phosphorylation ABL1;MMP9;LYN GO:2001243| negative regulation of intrinsic apoptotic signaling pathway MMP9;SRC 7112:[DB06616 DB05217] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB05217|GMX1777 NAMPT common genes common pathways GO:0007165| signal transduction LYN;BCR;SRC;MAP2K1;NAMPT GO:0014070| response to organic cyclic compound NAMPT;LYN GO:0008284| positive regulation of cell proliferation HCK;NAMPT;LYN;CDK2 7113:[DB06616 DB03632] DB06616|Bosutinib BCR;ABL1;LYN;HCK;SRC;CDK2;MAP2K1;MAP2K2;MAP3K2;CAMK2G;CYP3A4;CYP2C8;ABCB1 DB03632|Argifin CHIT1 common genes common pathways 7114:[DB07863 DB07543] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;ADRB2 GO:0009409| response to cold PPARG;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2 GO:0007165| signal transduction ADRB2;PPARG 7115:[DB07863 DB11730] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;CDK4 GO:0006367| transcription initiation from RNA polymerase II promoter CDK4;PPARG;RXRA GO:0007623| circadian rhythm NCOA2;CDK4 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043065| positive regulation of apoptotic process PPARG;CDK4 GO:0008285| negative regulation of cell proliferation PPARG;CDK6 GO:0010033| response to organic substance PPARG;CDK4 GO:0032869| cellular response to insulin stimulus PPARG;CDK4 GO:0007165| signal transduction CDK4;CDK6;PPARG GO:0031100| organ regeneration CDK4;PPARG 7116:[DB07863 DB00413] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0048511| rhythmic process NCOA2;DRD4;PPARG GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0007165| signal transduction PPARG;DRD4;HTR1A;ADRA2C;ADRA2B;HTR2A;DRD3;HTR1D;HTR2C;HTR2B;ADRA2A;DRD1;DRD2;HTR1B;DRD5 GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway HTR1D;DRD4;PPARG;HTR1A;ADRA2C;ADRA2B;HTR2A;DRD3;DRD2;HTR1B;DRD5;HTR2B;HTR2C;ADRA2A;DRD1 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;DRD3 GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug PPARG;DRD3;HTR2A;DRD2;HTR1B;HTR2B;HTR2C;DRD1 GO:0007507| heart development RXRA;PPARG;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;DRD3;RXRA;NCOA2 7117:[DB07863 DB01224] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01224|Quetiapine HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP3A4;CYP2C19;CYP2D6;ABCB1 common genes common pathways GO:0045600| positive regulation of fat cell differentiation HTR2C;HTR2A;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0048511| rhythmic process NCOA2;DRD4;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;DRD3;PPARG GO:0007186| G-protein coupled receptor signaling pathway CHRM4;DRD5;HTR7;DRD2;ADRA1A;HTR1B;HTR1E;DRD1;ADRA2A;ADRA1B;HTR2C;HTR6;HRH1;CHRM3;HTR1D;CHRM5;ADRA1D;CHRM2;DRD3;ADRA2B;HTR2A;CHRM1;ADRA2C;PPARG;DRD4;HTR1A GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0007165| signal transduction HTR1A;DRD4;PPARG;ADRA2C;CHRM1;HTR2A;ADRA2B;DRD3;CHRM2;ADRA1D;CHRM5;HTR1D;CHRM3;HRH1;HTR6;HTR2C;ADRA1B;ADRA2A;DRD1;HTR1E;HTR1B;ADRA1A;DRD2;HTR7;DRD5;CHRM4;HTR3A GO:0042493| response to drug DRD2;ADRA1A;ABCB1;HTR1B;HTR2C;DRD1;PPARG;DRD3;HTR2A GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0007623| circadian rhythm HTR7;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG;DRD2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;DRD3;NCOA2 7118:[DB07863 DB06605] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug PPARG;CYP1A2;ABCG2;ABCB1 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG 7119:[DB07863 DB01179] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0048511| rhythmic process NCOA2;PPARG;TOP2A GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process TOP2A;PPARG 7120:[DB07863 DB05127] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05127|ANA971 TLR7 common genes common pathways GO:0007165| signal transduction TLR7;PPARG GO:0045087| innate immune response TLR7;PPARG 7121:[DB07863 DB01148] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways GO:0007165| signal transduction PPARG;CHRM1;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1;CHRM2 7122:[DB07863 DB01594] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;PPARG GO:0007165| signal transduction GABRR2;GABRE;GABRA5;GABRB1;GABRD;PPARG;GABRP;GABRB3 7123:[DB07863 DB00196] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;CYP11B1 GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0032870| cellular response to hormone stimulus CYP11B1;NCOA2 GO:0042593| glucose homeostasis PPARG;CYP11B1 7124:[DB07863 DB08911] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;MAP2K1 GO:0008285| negative regulation of cell proliferation MAP2K1;PPARG GO:0007507| heart development MAP2K1;RXRA;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K2;MAP2K1;PPARG;RXRA 7125:[DB07863 DB01415] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 7126:[DB07863 DB00940] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00940|Methantheline CHRM1;HRH2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1;HRH2 GO:0007165| signal transduction CHRM1;PPARG;HRH2 7127:[DB07863 DB00816] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00816|Orciprenaline ADRB2 common genes common pathways GO:0009409| response to cold ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ADRB2;RXRA;NCOA2 GO:0007165| signal transduction ADRB2;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2 7128:[DB07863 DB00543] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression DRD2;NCOA2;DRD3 GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0042493| response to drug SLC6A2;HTR2A;DRD3;PPARG;ADRA1A;DRD2;HTR1B;DRD1;SLC6A3;GABRG3;HTR2B;HTR2C;SLC6A4 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;DRD3;NCOA2;DRD2 GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0007507| heart development PPARG;RXRA;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;DRD3;RXRA;PPARG GO:0007623| circadian rhythm HTR7;SLC6A4;NCOA2 GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0010033| response to organic substance SLC6A4;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0007584| response to nutrient SLC6A4;PPARG GO:0048511| rhythmic process NCOA2;PPARG;DRD4 GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0007165| signal transduction GABRE;CHRM5;ADRA1D;GABRQ;HRH1;CHRM3;GABRA5;GABRB1;GABRD;ADRA2C;CHRM1;HTR1A;GABRA6;DRD4;PPARG;DRD3;CHRM2;HTR2A;ADRA2B;GABRP;HRH4;HTR1B;DRD2;ADRA1A;HTR7;CHRM4;HTR3A;ADRA2A;GABRB3;HTR2C;HTR6;HTR2B;ADRA1B;DRD1 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;DRD3;RXRA GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;HTR2C;HTR6;HTR2B;ADRA1B;DRD1;HTR1B;DRD2;ADRA1A;HTR7;CHRM4;ADRA2C;CHRM1;HTR1A;DRD4;PPARG;DRD3;CHRM2;HTR2A;ADRA2B;HRH4;CHRM5;ADRA1D;CHRM3;HRH1 7129:[DB07863 DB00936] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG;CYP2C9;PTGS1;SLC16A1 GO:0042493| response to drug PTGS2;PPARG GO:0042593| glucose homeostasis SLC16A1;PPARG GO:0007566| embryo implantation PTGS2;RXRA GO:0015721| bile acid and bile salt transport NCOA2;RXRA;AKR1C1;ALB;SLCO2B1 GO:0008217| regulation of blood pressure PTGS1;PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0030855| epithelial cell differentiation PPARG;AKR1C1 7130:[DB07863 DB01165] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;TOP2A;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process TOP2A;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0042493| response to drug PPARG;CYP1A2;ABCC1;ABCC2 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 GO:0048511| rhythmic process NCOA2;PPARG;TOP2A GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 7131:[DB07863 DB01618] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0042493| response to drug PPARG;HTR2A;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0007186| G-protein coupled receptor signaling pathway DRD2;HTR1A;PPARG;CHRM1;HTR2A GO:0007165| signal transduction DRD2;PPARG;HTR1A;CHRM1;HTR2A 7132:[DB07863 DB01023] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 GO:0007165| signal transduction PDE1A;NR3C2;PDE1B;PPARG GO:0043010| camera-type eye development CACNA1C;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0007186| G-protein coupled receptor signaling pathway PDE1B;CALM1;PDE1A;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C2 GO:0030224| monocyte differentiation PDE1B;PPARG GO:0006355| regulation of transcription, DNA-dependent NR3C2;PPARG;RXRA;NCOA2 GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP2D6 GO:0007507| heart development RXRA;PPARG;CACNA1C GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;NR3C2 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C2 GO:0055010| ventricular cardiac muscle tissue morphogenesis TNNC1;RXRA 7133:[DB07863 DB01029] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;JUN GO:0042493| response to drug PPARG;JUN GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;JUN GO:0030224| monocyte differentiation PPARG;JUN GO:0009612| response to mechanical stimulus PPARG;JUN GO:0043065| positive regulation of apoptotic process JUN;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;JUN;NCOA2 GO:0006629| lipid metabolic process PTGS1;CYP2C9;PPARG;CYP3A4 GO:0007623| circadian rhythm JUN;NCOA2 GO:0006351| transcription, DNA-dependent PPARG;RXRA;JUN;NCOA2 GO:0008285| negative regulation of cell proliferation PPARG;JUN GO:0010033| response to organic substance JUN;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;JUN;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0014070| response to organic cyclic compound PPARG;JUN GO:0032870| cellular response to hormone stimulus NCOA2;JUN GO:0007165| signal transduction AGTR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;AGTR1 7134:[DB07863 DB00866] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0009409| response to cold ADRB3;ADRB1;PPARG;ADRB2 GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0007165| signal transduction ADRB3;ADRB1;ADRB2;HTR1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;HTR1A;ADRB2;ADRB3;ADRB1 7135:[DB07863 DB06233] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;MTOR GO:0007584| response to nutrient MTOR;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;MTOR GO:0006629| lipid metabolic process CYP3A4;PPARG 7136:[DB07863 DB00843] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug PPARG;HTR2A GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP2D6 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0007165| signal transduction PPARG;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;PPARG 7137:[DB07863 DB00987] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0051289| protein homotetramerization CDA;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0030308| negative regulation of cell growth PPARG;CDA 7138:[DB07863 DB14011] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes PPARG common pathways GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARG;NCOA2;AANAT GO:0007584| response to nutrient HMGCR;PPARG;CNR1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2;OPRM1;CYP1B1 GO:0010033| response to organic substance PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1;SOD1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PPARG;PTGS1 GO:0031000| response to caffeine PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1;RXRA GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2 GO:0007165| signal transduction CHRNA7;PLA2G1B;CACNA1I;HTR1A;PPARG;GPR55;GPR18;HTR2A;GPR12;CNR1;OPRM1;CNR2;SMPD1;OPRD1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0060694| regulation of cholesterol transporter activity PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;GPR18;HTR2A;CNR1;GPR12;GPR55;PPARG;HTR1A GO:1905461| PPARG GO:0007566| embryo implantation PTGS2;RXRA;SOD1 GO:0019216| regulation of lipid metabolic process CNR1;RXRA;PPARG;CYP1A1;HMGCR;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:1904706| PPARG GO:0051289| protein homotetramerization CRYZ;TRPA1;RXRA;CAT;TRPM8;TRPV1 GO:0071455| cellular response to hyperoxia PPARG GO:0016032| viral reproduction VDAC1;RXRA;HTR2A GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0030224| monocyte differentiation PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0042493| response to drug SMPD1;ABCC1;CYP1A2;PTGS2;HTR2A;SOD1;TRPA1;PPARG;CYP1A1;ABCG2;CAT GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;RXRA;PPARG;NCOA2 GO:0007507| heart development RXRA;PPARG GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;CYP2C9;PPARG;NAAA;PTGS1;GPX1;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;PTGS2;SMPD1;PPARG;SOD1;CNR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;RXRA;PPARG;NCOA2 GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA GO:0008203| cholesterol metabolic process HMGCR;RXRA;CAT GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0007623| circadian rhythm NCOA2;AANAT GO:0030308| negative regulation of cell growth PPARG 7139:[DB07863 DB08877] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;JAK2 GO:0045087| innate immune response JAK1;JAK2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043065| positive regulation of apoptotic process JAK2;PPARG GO:0006919| activation of caspase activity PPARG;JAK2 GO:0008285| negative regulation of cell proliferation JAK2;PPARG GO:0007186| G-protein coupled receptor signaling pathway JAK2;PPARG GO:0007165| signal transduction PPARG;JAK2 GO:0043388| positive regulation of DNA binding PPARG;JAK2 7140:[DB07863 DB11641] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug ABCB1;PPARG 7141:[DB07863 DB00292] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRA2B GO:0007165| signal transduction GABRB3;GABRD;GABRA6;PPARG;GABRP;ADRA2B;GABRE;GABRQ;GABRA5;GABRB1 GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0006629| lipid metabolic process CYP11B2;CYP11B1;PPARG GO:0042493| response to drug GABRG3;PPARG 7142:[DB07863 DB01218] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 7143:[DB07863 DB01099] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01099|Flucytosine DNMT1 common genes common pathways GO:0006351| transcription, DNA-dependent DNMT1;RXRA;PPARG;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;DNMT1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;DNMT1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;DNMT1 7144:[DB07863 DB01204] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0042493| response to drug PPARG;CYP2E1;ABCC1;ABCG2;ABCB1 GO:0043065| positive regulation of apoptotic process CYP1B1;TOP2A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TOP2A;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0048511| rhythmic process NCOA2;TOP2A;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1 7145:[DB07863 DB06267] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007165| signal transduction PDE5A;PPARG 7146:[DB07863 DB01198] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0043065| positive regulation of apoptotic process TSPO;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;PTGS1 GO:0042493| response to drug TSPO;CYP2E1;PPARG GO:0007165| signal transduction PPARG;TSPO;GABRA5 GO:0008217| regulation of blood pressure PTGS1;PPARG 7147:[DB07863 DB00854] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRD1;OPRM1;OPRK1 GO:0007165| signal transduction PPARG;OPRD1;OPRM1;OPRK1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus OPRK1;PPARG 7148:[DB07863 DB14050] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0042493| response to drug PPARG;TRPA1 GO:0051289| protein homotetramerization TRPV1;TRPA1;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;NCOA2;RXRA;PPARG GO:0006629| lipid metabolic process TRPV1;DAGLA;PPARG GO:0043065| positive regulation of apoptotic process PPARG;TRPV1 GO:0009409| response to cold PPARG;TRPA1 GO:0014070| response to organic cyclic compound PPARG;TRPA1 GO:0010033| response to organic substance TRPA1;PPARG 7149:[DB07863 DB00622] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG;ABCB1;ADRA1A GO:0030224| monocyte differentiation PPARG;PDE1B GO:0007507| heart development RXRA;PPARG;CACNA1C GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;ABCB11;NCOA2 GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway CHRM1;PPARG;CHRM2;ADRA1D;CHRM5;CHRM3;CALM1;ADRA1B;PDE1A;ADRA1A;PDE1B;CHRM4 GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0043010| camera-type eye development CACNA1C;RXRA GO:0007165| signal transduction CHRM2;CHRM1;PPARG;CHRM3;CHRM5;ADRA1D;PDE1A;ADRA1B;CHRM4;PDE1B;ADRA1A 7150:[DB07863 DB01232] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01232|Saquinavir pol;CYP3A7;CYP3A5;CYP3A4;CYP11A1;CYP2C8;CYP2D6;ORM1;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;ABCC1;ABCC2;SLCO2B1;ABCB11 common genes common pathways GO:0042493| response to drug PPARG;ABCC1;ABCG2;ABCC2;ABCB1 GO:0006629| lipid metabolic process CYP11A1;CYP3A4;PPARG;CYP2D6 GO:0008203| cholesterol metabolic process CYP11A1;RXRA GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1A2;NCOA2;SLCO1B1;RXRA;ABCB11 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 7151:[DB07863 DB00370] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0007507| heart development HTR2B;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RXRA;DRD3;PPARG;NCOA2;DRD2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0009409| response to cold ADRB1;PPARG;ADRB2 GO:0007623| circadian rhythm NCOA2;HTR7;SLC6A4 GO:0032922| circadian regulation of gene expression DRD2;NCOA2;DRD3 GO:0016032| viral reproduction HTR2A;RXRA GO:0042493| response to drug DRD1;SLC6A3;HTR2B;HTR2C;SLC6A4;ADRA1A;DRD2;HTR2A;DRD3;PPARG;SLC6A2;CYP1A2 GO:0007165| signal transduction ADRA2A;HTR2C;HTR2B;ADRA1B;OPRK1;DRD1;ADRB1;DRD2;ADRA1A;DRD5;HTR7;HTR3A;ADRA2C;PPARG;DRD3;HTR2A;ADRB2;ADRA1D;HRH1;HRH3 GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway DRD5;HTR7;DRD2;ADRA1A;ADRB1;OPRK1;DRD1;ADRA2A;ADRA1B;HTR2C;HTR2B;HRH1;HRH3;ADRA1D;DRD3;ADRB2;HTR2A;ADRA2C;PPARG GO:0019216| regulation of lipid metabolic process DRD3;RXRA;PPARG;NCOA2 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance CYP1A2;PPARG;SLC6A4 GO:0008285| negative regulation of cell proliferation PPARG;DRD2;ADRA1A GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;HTR2C GO:0014070| response to organic cyclic compound SLC6A3;CYP1A2;PPARG 7152:[DB07863 DB01118] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes PPARG common pathways GO:0071300| cellular response to retinoic acid PPARG GO:0009409| response to cold PPARG;THRA;ADRB1 GO:0009612| response to mechanical stimulus PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;RXRA;PPARG;NCOA2;THRA GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4;PPARG;CYP2C9 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARG;RXRA GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;PPARG;RXRA;NCOA2 GO:0045165| cell fate commitment PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;PPARG;RXRA;THRA GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;THRA;THRB GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0006351| transcription, DNA-dependent THRB;PPARG;RXRA;THRA;NCOA2 GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid RXRA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;THRA;THRB GO:0071455| cellular response to hyperoxia PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CYP1A1;PPARG GO:1904706| PPARG GO:0006367| transcription initiation from RNA polymerase II promoter THRB;PPARG;RXRA;THRA GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA GO:0042493| response to drug PPARG;CYP1A1;CYP1A2;ABCB1 GO:0006355| regulation of transcription, DNA-dependent THRB;THRA;NCOA2;PPARG;RXRA GO:0061614| PPARG GO:0030224| monocyte differentiation PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction ADRB1;PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRB1;PPARG GO:1905461| PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0001890| placenta development RXRA;PPARG GO:0019395| fatty acid oxidation PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0008217| regulation of blood pressure PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;THRA;PPARG;THRB GO:0031000| response to caffeine PPARG GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0007584| response to nutrient PPARG GO:0048511| rhythmic process NCOA2;PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG 7153:[DB07863 DB00392] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0042493| response to drug BCHE;PPARG GO:0007165| signal transduction CHRM2;CHRM1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1;CHRM2 GO:0007584| response to nutrient BCHE;PPARG GO:0008285| negative regulation of cell proliferation BCHE;PPARG 7154:[DB07863 DB00768] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;HRH1 GO:0007186| G-protein coupled receptor signaling pathway HRH1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;S100A1;PPARG GO:0045087| innate immune response S100B;S100A12;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;S100B 7155:[DB07863 DB00483] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0007165| signal transduction CHRM5;CHRM1;PPARG;CHRM2;CHRNA2 GO:0007186| G-protein coupled receptor signaling pathway CHRM5;CHRM1;PPARG;CHRM2 7156:[DB07863 DB00300] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0043388| positive regulation of DNA binding PPARG;NME1 GO:0008285| negative regulation of cell proliferation PPARG;NME1 GO:0010033| response to organic substance ABCC4;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0014070| response to organic cyclic compound ABCC4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NME2 GO:0006351| transcription, DNA-dependent NME2;PPARG;RXRA;NCOA2 GO:0042493| response to drug ABCB1;ABCC4;ABCC2;NME1;AK4;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;NME2 7157:[DB07863 DB00960] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0042493| response to drug HTR1B;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RXRA;PPARG;NCOA2 GO:0009409| response to cold ADRB2;PPARG;ADRB1;ADRB3 GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;HTR1B;ADRB3;HTR1A;PPARG;ADRB2 GO:0007165| signal transduction ADRB1;HTR1B;ADRB3;PPARG;HTR1A;ADRB2 7158:[DB07863 DB14568] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4 GO:0042493| response to drug PPARG;ABCB1 GO:0014070| response to organic cyclic compound PPARG;IDH1 7159:[DB07863 DB09273] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADORA2A;ADRB2;PPARG;PDE2A GO:0007165| signal transduction PPARG;ADORA2A;ADRB2;PDE2A GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation ADORA2A;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0031000| response to caffeine PPARG;ADORA2A GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;PDE2A GO:0009409| response to cold PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0030224| monocyte differentiation PDE2A;PPARG GO:0042493| response to drug ADORA2A;PPARG;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;ADORA2A 7160:[DB07863 DB00290] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0042493| response to drug BLMH;PPARG 7161:[DB07863 DB14597] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14597|Lanadelumab KLKB1 common genes common pathways 7162:[DB07863 DB00945] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;PTGS2;TP53 GO:0010745| negative regulation of macrophage derived foam cell differentiation NFKBIA;PPARG GO:0030855| epithelial cell differentiation PPARG;AKR1C1 GO:0019395| fatty acid oxidation PRKAA1;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG;PRKAA2;PRKAA1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA;AKR1C1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;TP53;PPARG;NFKB1 GO:0008217| regulation of blood pressure PPARG;EDNRA;PTGS2;PTGS1 GO:0031000| response to caffeine PRKAA1;TP53;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;TP53;PPARG GO:0010033| response to organic substance PTGS2;PPARG GO:0048511| rhythmic process TP53;NCOA2;NFKB2;PPARG;PRKAA2;PRKAA1 GO:0007566| embryo implantation RXRA;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;EDNRA GO:0048662| negative regulation of smooth muscle cell proliferation TP53;PPARG GO:0042593| glucose homeostasis PRKAA1;PRKAA2;PPARG GO:0007165| signal transduction PRKAA2;RPS6KA3;EDNRA;PPARG;NFKB2;PRKAG1;PRKAB2;PRKAB1;NFKB1;PRKAA1 GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;NFKBIA;IKBKB;RXRA;PPARG;TP53 GO:0006355| regulation of transcription, DNA-dependent NFKB1;PRKAA1;PPARG;PRKAA2;NFKB2;RXRA;TP53;NCOA2 GO:0042493| response to drug PPARG;TP53;PTGS2;ABCB1 GO:0016032| viral reproduction NFKBIA;TP53;RXRA GO:0051289| protein homotetramerization RXRA;TP53 GO:0001701| in utero embryonic development EDNRA;RXRA GO:0042752| regulation of circadian rhythm PRKAA1;PPARG;PRKAA2 GO:0030308| negative regulation of cell growth TP53;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;PPARG;RXRA GO:0008203| cholesterol metabolic process PRKAA1;RXRA;PRKAA2 GO:0006351| transcription, DNA-dependent NCOA2;TP53;RXRA;NFKB2;PRKAA2;PPARG;PRKAA1;NFKB1 GO:0032526| response to retinoic acid TP53;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TP53;RPS6KA3;PPARG;NFKB2;RXRA;IKBKB;NFKBIA;NFKB1 GO:0043065| positive regulation of apoptotic process PTGS2;TP53;PPARG GO:0051974| negative regulation of telomerase activity TP53;PPARG GO:0006629| lipid metabolic process PRKAG2;PRKAG1;PTGS2;CYP2C9;PPARG;PRKAA2;PTGS1;PRKAA1;PRKAB1;PRKAB2;PRKAG3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;NFKB2;PPARG;TP53;NCOA2;NFKB1 GO:0045087| innate immune response NFKB1;NFKB2;IKBKB;PPARG GO:0007507| heart development RXRA;PPARG;EDNRA 7163:[DB07863 DB00296] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0042493| response to drug PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 7164:[DB07863 DB01087] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0016032| viral reproduction RXRA;KRT7 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug CYP1A2;CYP1A1;PPARG;ABCB1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 7165:[DB07863 DB11753] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1B3;SLCO1B1;RXRA;SLCO1A2;NCOA2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0042493| response to drug PPARG;CYP1A2;ABCB1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2C9;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG 7166:[DB07863 DB01124] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0042493| response to drug ABCC8;PPARG GO:0016525| negative regulation of angiogenesis ABCC8;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;NCOA2;SLCO1A2;RXRA GO:0007165| signal transduction ABCC8;PPARG 7167:[DB07863 DB00997] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;TOP2A;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;NOS1;TOP2A GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0007623| circadian rhythm NOS2;NCOA2 GO:0030308| negative regulation of cell growth PPARG;NDUFS3 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0001701| in utero embryonic development RXRA;NOS3 GO:0042493| response to drug ABCG2;ABCC2;POR;ABCB1;PPARG;ABCC6;ABCC1 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;PPARG;RXRA GO:0071379| cellular response to prostaglandin stimulus PPARG;AKR1C3 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007165| signal transduction PPARG;RALBP1 GO:0007186| G-protein coupled receptor signaling pathway AKR1C3;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2;ABCC3;ALB GO:0019395| fatty acid oxidation PPARG;POR GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient AKR1C3;NQO1;PPARG;POR GO:0048511| rhythmic process NCOA2;TOP2A;PPARG GO:0008285| negative regulation of cell proliferation PPARG;NOS3;CYP1B1 GO:0008217| regulation of blood pressure PPARG;NOS3 GO:0006919| activation of caspase activity PPARG;XDH GO:0014070| response to organic cyclic compound PPARG;NQO1 GO:0030855| epithelial cell differentiation CBR1;PPARG 7168:[DB07863 DB00266] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG GO:0051289| protein homotetramerization RXRA;CRYZ GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0007584| response to nutrient PPARG;NQO1 GO:0014070| response to organic cyclic compound NQO1;PPARG 7169:[DB07863 DB11587] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11587|Etafedrine ADRB2 common genes common pathways GO:0009409| response to cold ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ADRB2;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG GO:0007165| signal transduction ADRB2;PPARG 7170:[DB07863 DB14583] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0001701| in utero embryonic development RXRA;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;PGR;PPARG;RXRA;NR3C1 GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;NR3C1;AR;PGR GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NR3C1;NCOA2;AR;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1;AR GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR GO:0006351| transcription, DNA-dependent RXRA;PPARG;NR3C1;NCOA2;AR;PGR GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA;PGR;AR GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0007165| signal transduction PPARG;NR3C1;AR;PGR 7171:[DB07863 DB08867] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0010033| response to organic substance CYP1A2;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007165| signal transduction AR;PGR;PPARG;NR3C1 GO:0001701| in utero embryonic development AR;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PGR;AR;NR3C1;PPARG;RXRA GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0006355| regulation of transcription, DNA-dependent AR;PGR;PPARG;RXRA;NR3C1;NCOA2 GO:0042493| response to drug CYP1A2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AR;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1;AR GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;RXRA;PPARG;NR3C1;NCOA2 GO:0006351| transcription, DNA-dependent AR;PGR;PPARG;RXRA;NR3C1;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR3C1;AR;PGR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;AR 7172:[DB07863 DB01251] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0007165| signal transduction ABCC8;PPARG GO:0042493| response to drug ABCC8;PPARG GO:0016525| negative regulation of angiogenesis PPARG;ABCC8 GO:0007507| heart development KCNJ8;PPARG;RXRA GO:0006629| lipid metabolic process CYP2C9;PPARG 7173:[DB07863 DB09235] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0043010| camera-type eye development RXRA;CACNA1C GO:0007165| signal transduction PPARG;CACNA1I GO:0007507| heart development RXRA;PPARG;CACNA1C GO:0006629| lipid metabolic process PPARG;CYP3A4 7174:[DB07863 DB04725] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PLA2G2E;PPARG;CYP2C9;PTGS2 GO:0042493| response to drug PPARG;PTGS2 GO:0007566| embryo implantation PTGS2;RXRA GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0010033| response to organic substance PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG 7175:[DB07863 DB00153] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0030308| negative regulation of cell growth CYP27B1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;VDR GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;NCOA2;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;VDR GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;VDR GO:0006766| vitamin metabolic process CYP24A1;CYP2R1;CYP27B1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;VDR GO:0007165| signal transduction VDR;PPARG GO:0043627| response to estrogen stimulus CYP27B1;PPARG GO:0008285| negative regulation of cell proliferation VDR;CYP27B1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;VDR 7176:[DB07863 DB00358] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0007165| signal transduction ADORA2A;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADORA2A GO:0008285| negative regulation of cell proliferation BCHE;ADORA2A;PPARG GO:0031000| response to caffeine ADORA2A;PPARG GO:0007584| response to nutrient BCHE;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG GO:0042493| response to drug BCHE;PPARG;ADORA2A;ABCB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;ADORA2A;RXRA;PPARG 7177:[DB07863 DB09256] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound CYP1A2;TYMS;PPARG GO:0033189| response to vitamin A TYMS;PPARG GO:0042493| response to drug CYP2E1;PPARG;TYMS;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP1A2 GO:0007623| circadian rhythm TYMS;NCOA2 7178:[DB07863 DB09229] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRA2A;ADRA1B;ADRA1D;ADRA2B;ADRA2C;PPARG GO:0043010| camera-type eye development CACNA1C;RXRA GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0007165| signal transduction ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;PPARG;ADRA2C GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development RXRA;PPARG;CACNA1C GO:0042493| response to drug PPARG;ADRA1A 7179:[DB07863 DB09078] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;FGFR1;PPARG;FGFR2 GO:0045165| cell fate commitment PPARG;FGFR2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;FGFR2 GO:0071300| cellular response to retinoic acid FGFR2;PPARG GO:0048469| cell maturation PPARG;FGFR1 GO:0055010| ventricular cardiac muscle tissue morphogenesis FGFR2;RXRA GO:0006351| transcription, DNA-dependent RXRA;PPARG;FGFR1;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;KIT GO:0001701| in utero embryonic development RXRA;FGFR1;FGFR2 GO:0060687| regulation of branching involved in prostate gland morphogenesis FGFR2;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0016032| viral reproduction KDR;RXRA GO:0042493| response to drug ABCG2;ABCB1;PPARG;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;FGFR1;RXRA GO:0007165| signal transduction KIT;PPARG GO:0042593| glucose homeostasis PPARG;FGFR4 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;FGFR4 GO:0010033| response to organic substance CYP1A2;PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;ABCB11;NCOA2 GO:0030855| epithelial cell differentiation PPARG;FGFR2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 7180:[DB07863 DB00417] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 7181:[DB07863 DB11691] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0007165| signal transduction PPARG;OPRD1;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PPARG;OPRK1 GO:0006629| lipid metabolic process CYP3A4;PPARG 7182:[DB07863 DB00738] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0042493| response to drug PPARG;CYP1A1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0010033| response to organic substance CYP1A1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;CYP4A11;RXRA;CYP1A1;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA 7183:[DB07863 DB00882] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0010033| response to organic substance CYP1A1;PPARG;CYP1A2 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0007165| signal transduction ESR1;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;ESR1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;ESR1 GO:0042493| response to drug CYP1A2;CYP2E1;CYP1A1;PPARG;ABCB1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP11A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2 GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;ESR1;PPARG GO:0008203| cholesterol metabolic process CYP11A1;RXRA 7184:[DB07863 DB01248] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0006919| activation of caspase activity PPARG;MAPT GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B3 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;BCL2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007165| signal transduction PPARG;NR1I2 GO:0042493| response to drug PPARG;BCL2;ABCC1;ABCC2;ABCG2;ABCB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;RXRA GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR1I2 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;NR1I2;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 7185:[DB07863 DB00497] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0007165| signal transduction OPRK1;PPARG;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 7186:[DB07863 DB08931] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug ABCG2;CYP1A1;PPARG GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 GO:0007165| signal transduction PPARG;GUCY1A2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0010033| response to organic substance PPARG;CYP1A1 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB 7187:[DB07863 DB00332] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0007165| signal transduction CHRM3;CHRM2;CHRM1;PPARG GO:0007186| G-protein coupled receptor signaling pathway CHRM3;CHRM2;PPARG;CHRM1 7188:[DB07863 DB06780] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;NR3C2 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C2;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent NR3C2;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;NR3C2 GO:0043401| steroid hormone mediated signaling pathway NR3C2;RXRA;PPARG 7189:[DB07863 DB02750] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 7190:[DB07863 DB06216] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0042493| response to drug HTR1B;ADRA1A;DRD2;HTR2B;HTR2C;DRD1;CYP1A2;PPARG;DRD3;HTR2A GO:0032922| circadian regulation of gene expression DRD2;NCOA2;DRD3 GO:0016032| viral reproduction HTR2A;RXRA GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0007623| circadian rhythm NCOA2;HTR7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;ADRB2;PPARG;DRD2 GO:0009409| response to cold ADRB1;ADRB2;PPARG GO:0007507| heart development RXRA;PPARG;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD3 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0048511| rhythmic process NCOA2;DRD4;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway DRD3;HRH2;HTR2A;ADRB2;ADRA2B;ADRA2C;HTR1A;PPARG;DRD4;HRH1;DRD1;ADRA2A;HTR2B;HTR6;HTR2C;HTR5A;HTR7;HTR1B;ADRB1;ADRA1A;DRD2 GO:0019216| regulation of lipid metabolic process RXRA;DRD3;PPARG;NCOA2 GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007165| signal transduction HTR2C;HTR2B;HTR6;HTR5A;ADRA2A;DRD1;ADRB1;HTR1B;DRD2;ADRA1A;HTR7;HTR1A;PPARG;DRD4;ADRA2C;HTR2A;ADRA2B;ADRB2;DRD3;HRH2;HRH1 7191:[DB07863 DB00228] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0007165| signal transduction GABRB3;ATP2C1;GRIA1;GABRP;GABRD;PPARG;GABRA6;GABRQ;GABRB1;GABRA5;GABRE GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0042493| response to drug PPARG;CYP2E1;GABRG3 7192:[DB07863 DB00663] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NR3C1;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR3C1;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG GO:0007165| signal transduction NR3C1;PPARG 7193:[DB07863 DB01282] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01282|Carbetocin OXTR common genes common pathways GO:0014070| response to organic cyclic compound OXTR;PPARG GO:0007186| G-protein coupled receptor signaling pathway OXTR;PPARG GO:0007165| signal transduction PPARG;OXTR GO:0032870| cellular response to hormone stimulus OXTR;NCOA2 GO:0042493| response to drug OXTR;PPARG GO:0007507| heart development PPARG;OXTR;RXRA 7194:[DB07863 DB00477] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00477|Chlorpromazine DRD2;DRD1;HTR1A;HTR2A;ADRA1A;ADRA1B;HRH1;KCNH2;DRD1;DRD5;DRD3;DRD4;DRD5;HTR2C;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM3;SMPD1;CALM1;ORM1;ORM2;HTR6;HTR7;HRH4;CYP2D6;CYP1A2;CYP2E1;CYP3A4;BCHE;ALB;ABCB1;ABCB11 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR1A;DRD4;PPARG;ADRA2C;CHRM1;HTR2A;HRH4;ADRA2B;DRD3;ADRA1D;CHRM3;HRH1;HTR2B;HTR6;HTR2C;ADRA1B;ADRA2A;CALM1;DRD1;ADRA1A;DRD2;HTR7;DRD5 GO:0019216| regulation of lipid metabolic process RXRA;DRD3;PPARG;NCOA2 GO:0042593| glucose homeostasis PPARG;ADRA2A;ADRA1B GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007165| signal transduction DRD3;ADRA2B;HRH4;HTR2A;CHRM1;ADRA2C;PPARG;DRD4;HTR1A;HRH1;CHRM3;SMPD1;ADRA1D;DRD1;ADRA2A;ADRA1B;HTR2C;HTR6;HTR2B;DRD5;HTR7;DRD2;ADRA1A GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0015721| bile acid and bile salt transport NCOA2;ABCB11;RXRA;ALB GO:0007584| response to nutrient PPARG;BCHE GO:0048511| rhythmic process NCOA2;DRD4;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;BCHE;PPARG GO:0007623| circadian rhythm HTR7;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;DRD3;RXRA;PPARG GO:0043065| positive regulation of apoptotic process PPARG;SMPD1 GO:0007507| heart development RXRA;PPARG;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4;CYP1A2 GO:0042493| response to drug HTR2C;HTR2B;DRD1;ABCB1;DRD2;ADRA1A;CYP2E1;PPARG;HTR2A;DRD3;CYP1A2;BCHE;SMPD1 GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0042752| regulation of circadian rhythm DRD4;PPARG 7195:[DB07863 DB00226] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00226|Guanadrel SLC6A2 common genes common pathways GO:0042493| response to drug PPARG;SLC6A2 7196:[DB07863 DB01373] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CALM1;PPARG GO:0043010| camera-type eye development BMP4;RXRA;CACNA1C GO:0007165| signal transduction PPARG;ATP2C1 GO:0006919| activation of caspase activity S100A8;S100A9;PPARG;PDCD6 GO:0045892| negative regulation of transcription, DNA-dependent BMP4;PPARG;NCOA2 GO:0008285| negative regulation of cell proliferation PPARG;BMP4 GO:0043401| steroid hormone mediated signaling pathway BMP4;PPARG;RXRA GO:0055010| ventricular cardiac muscle tissue morphogenesis TNNC1;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;BMP4;PPARG;RXRA GO:0043065| positive regulation of apoptotic process BMP4;PPARG;S100B GO:0045165| cell fate commitment PPARG;BMP4 GO:0007507| heart development CACNA1C;BMP4;PPARG;RXRA GO:0045087| innate immune response S100A9;S100A8;PPARG;S100B GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;BMP4 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;BMP4;PPARG GO:0042493| response to drug AOC1;PPARG GO:0030224| monocyte differentiation BMP4;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;BMP4 7197:[DB07863 DB09209] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;PPARG;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG 7198:[DB07863 DB13179] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG GO:0042493| response to drug ABCB1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2;NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;NR1I2;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RXRA;PPARG GO:0006351| transcription, DNA-dependent PPARG;NR1I2;RXRA;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1I2;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2 GO:0007165| signal transduction NR1I2;PPARG 7199:[DB07863 DB01435] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A2;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2;CYP1A2 GO:0007566| embryo implantation RXRA;PTGS2 GO:0042493| response to drug CYP2E1;PPARG;PTGS2;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PTGS1;CYP2D6;PTGS2;CYP1A2;CYP3A4;PPARG;CYP2C9 7200:[DB07863 DB00898] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0019216| regulation of lipid metabolic process NCOA2;CYP4A11;RXRA;CYP1A1;PPARG GO:0007165| signal transduction GABRE;CHRNB2;HTR3E;GABRB1;GABRA5;GABRQ;CHRNA6;HTR3C;PPARG;CHRNA9;GABRA6;GABRD;GABRP;CHRNB4;CHRNA4;CHRNA3;GRIA2;CHRNA5;HTR3D;CHRNA10;GRIA1;CHRNA2;HTR3B;CHRNB3;HTR3A;GABRB3;CHRNA7 GO:0043010| camera-type eye development CYP1A1;RXRA;CACNA1C GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0007584| response to nutrient VCAM1;PPARG GO:0010033| response to organic substance CYP1A1;PPARG;CYP1A2 GO:0007507| heart development RXRA;PPARG;CACNA1C GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2C9 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042493| response to drug GABRG3;PPARG;CYP1A1;CYP2E1;CYP1A2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0016032| viral reproduction RXRA;VCAM1 7201:[DB07863 DB00197] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes PPARG common pathways GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration UGT1A1;PPARG;GSTP1 GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0007165| signal transduction PPARG GO:0019216| regulation of lipid metabolic process UGT1A9;NCOA2;CYP1A1;PPARG;PPARA;RXRA GO:0007566| embryo implantation PPARD;RXRA GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;GSTP1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARD;RXRA;PPARG GO:0019395| fatty acid oxidation PPARD;PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;ABCB11;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARD;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance UGT1A1;PPARD;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG GO:0008217| regulation of blood pressure PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;PPARD GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;PPARA;NCOA2 GO:0007584| response to nutrient ACSL4;PPARG;UGT1A1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;PPARG GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0071300| cellular response to retinoic acid PPARG GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRA;SERPINE1;ESRRG;PPARG;PPARA;RXRA;NCOA2 GO:0006629| lipid metabolic process UGT2B7;ACSL4;PPARD;PPARA;CYP3A4;CYP2C9;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0007507| heart development PPARA;PPARG;RXRA;PPARD GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;NCOA2;PPARD;RXRA;PPARA;PPARG GO:0045165| cell fate commitment PPARG GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0008203| cholesterol metabolic process PPARD;RXRA GO:0007623| circadian rhythm NCOA2;SERPINE1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;PPARD GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway ESRRA;ESRRG;PPARA;PPARG;RXRA;PPARD GO:0006351| transcription, DNA-dependent ESRRA;ESRRG;PPARA;PPARG;RXRA;NCOA2;PPARD GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid RXRA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0030522| intracellular receptor mediated signaling pathway PPARD;NCOA2;PPARA;ESRRA GO:0032922| circadian regulation of gene expression PPARA;NCOA2 GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;PPARD GO:0016525| negative regulation of angiogenesis PPARG GO:1904706| PPARG;GSTP1 GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESRRG;ESRRA;PPARD;PPARG;PPARA;RXRA GO:0050872| white fat cell differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARD;RXRA;PPARG;PPARA;ESRRG;ESRRA GO:0042493| response to drug CYP1A1;PPARG;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent ESRRG;ESRRA;NCOA2;PPARD;RXRA;PPARA;PPARG GO:0061614| PPARG GO:0048384| retinoic acid receptor signaling pathway ESRRG;RXRA GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0030224| monocyte differentiation PPARG 7202:[DB07863 DB01186] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug DRD3;HTR2A;PPARG;DRD1;HTR2B;HTR2C;ADRA1A;DRD2;HTR1B GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;DRD3;RXRA GO:0007507| heart development RXRA;PPARG;HTR2B GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0048511| rhythmic process NCOA2;DRD4;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;DRD3;RXRA GO:0007186| G-protein coupled receptor signaling pathway DRD5;HTR1B;ADRA1A;DRD2;DRD1;HTR2B;HTR2C;ADRA1B;ADRA2A;HTR1D;ADRA1D;HTR2A;ADRA2B;DRD3;HTR1A;PPARG;DRD4;ADRA2C GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0007165| signal transduction DRD1;ADRA2A;HTR2C;HTR2B;ADRA1B;DRD5;HTR1B;DRD2;ADRA1A;DRD3;HTR2A;ADRA2B;ADRA2C;HTR1A;PPARG;DRD4;HTR1D;ADRA1D 7203:[DB07863 DB11569] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11569|Ixekizumab IL17A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;IL17A;NCOA2 7204:[DB07863 DB01032] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0016032| viral reproduction RXRA;SLC10A1 GO:0042493| response to drug ABCC6;ABCC1;UGT1A1;PPARG;ABCC4;ABCC2;SLC22A12 GO:0006629| lipid metabolic process CYP3A4;PPARG;SLC16A1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport RXRA;ABCC3;SLCO1A2;SLCO1C1;NCOA2;ALB;SLC10A1 GO:0010033| response to organic substance ABCC4;PPARG;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0014070| response to organic cyclic compound UGT1A1;PPARG;ABCC4 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;ABCC2 GO:0042593| glucose homeostasis SLC16A1;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction TAS2R16;PPARG GO:0007186| G-protein coupled receptor signaling pathway TAS2R16;PPARG 7205:[DB07863 DB00628] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRP;GABRA6;PPARG;GABRD;TSPO;GABRA5;GABRB1;GABRQ;GABRE;GABRB3 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process TSPO;PPARG GO:0042493| response to drug GABRG3;TSPO;PPARG 7206:[DB07863 DB09089] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0043065| positive regulation of apoptotic process KCNMA1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007507| heart development PPARG;RXRA;CACNA1C GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0043010| camera-type eye development CACNA1C;RXRA GO:0007165| signal transduction CHRM1;PPARG;CHRM2;OPRM1;CHRM3;CACNA1I;CHRM4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CHRM3;PPARG;CHRM1;CHRM2;CHRM4 7207:[DB07863 DB09570] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0042493| response to drug CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A2 7208:[DB07863 DB08815] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0042493| response to drug DRD2;HTR2A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;DRD2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007623| circadian rhythm NCOA2;HTR7 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0007165| signal transduction ADRA2C;HTR1A;PPARG;HTR2A;ADRA2A;DRD2;HTR7 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;HTR1A;PPARG;ADRA2C;ADRA2A;HTR7;DRD2 7209:[DB07863 DB00400] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP1A2;CYP2D6 GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 7210:[DB07863 DB00468] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1;CYP1A1;PPARG;CYP1A2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2C9;CYP3A4;CYP2D6 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;SLCO1A2;NCOA2 GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA 7211:[DB07863 DB00208] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2C9;CYP2D6 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0009612| response to mechanical stimulus MPO;PPARG GO:0042493| response to drug CYP1A1;PPARG;CYP2E1;CYP1A2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway P2RY12;PPARG GO:0007165| signal transduction PPARG;P2RY12 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 7212:[DB07863 DB01021] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0008217| regulation of blood pressure ATP1A1;PPARG GO:0010033| response to organic substance PPARG;CA2 GO:0042493| response to drug ATP1A1;PPARG 7213:[DB07863 DB00824] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0008285| negative regulation of cell proliferation ADORA2A;ADORA3;PPARG;ADORA1 GO:0031000| response to caffeine PPARG;ADORA2A GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0007165| signal transduction ADORA1;PPARG;ADORA3;ADORA2A;PDE4A;PDE4B;ADORA2B GO:0007186| G-protein coupled receptor signaling pathway ADORA2B;PDE4B;PDE4A;ADORA1;PPARG;ADORA2A;ADORA3 GO:0042493| response to drug ADORA2A;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;ADORA2A 7214:[DB07863 DB08906] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NR3C1;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0015721| bile acid and bile salt transport NCOA2;SLCO1B1;RXRA GO:0007165| signal transduction PPARG;NR3C1 7215:[DB07863 DB02546] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;HDAC3 GO:0045892| negative regulation of transcription, DNA-dependent HDAC1;HDAC6;PPARG;NCOA2;HDAC3;HDAC2 GO:0031000| response to caffeine HDAC2;PPARG;HDAC1 GO:0010033| response to organic substance HDAC6;PPARG GO:0008285| negative regulation of cell proliferation PPARG;HDAC1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC1;HDAC2 GO:0048511| rhythmic process NCOA2;HDAC1;PPARG;HDAC2 GO:0006351| transcription, DNA-dependent HDAC3;HDAC8;HDAC2;NCOA2;HDAC1;RXRA;PPARG;HDAC6 GO:0045598| regulation of fat cell differentiation HDAC6;PPARG GO:0007623| circadian rhythm HDAC3;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;HDAC1;RXRA;NCOA2;HDAC2;HDAC8;HDAC3 GO:0071300| cellular response to retinoic acid HDAC2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;HDAC3;NCOA2;PPARG;RXRA;HDAC1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC1;RXRA;PPARG;HDAC2 GO:0006355| regulation of transcription, DNA-dependent HDAC2;HDAC8;HDAC3;NCOA2;HDAC6;PPARG;RXRA;HDAC1 GO:0042493| response to drug HDAC2;HDAC1;PPARG GO:0016032| viral reproduction RXRA;HDAC1 GO:0032922| circadian regulation of gene expression NCOA2;HDAC1;HDAC2 7216:[DB07863 DB11124] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;ADRB2;PPARG GO:0009409| response to cold PPARG;ADRB2;ADRB3;ADRB1 GO:0042493| response to drug PPARG;ADRA1A GO:0042593| glucose homeostasis ADRA2A;ADRA1B;PPARG GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007165| signal transduction PPARG;ADRA2C;ADRA2B;ADRB2;ADRA1D;ADRA1B;ADRA2A;ADRB3;ADRA1A;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;ADRA1A;ADRA2A;ADRA1B;ADRB3;ADRA1D;ADRA2C;PPARG;ADRA2B;ADRB2 GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG 7217:[DB07863 DB09363] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0042493| response to drug PPARG;MAOB;SLC6A2 7218:[DB07863 DB00912] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes PPARG common pathways GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG GO:0035902| response to immobilization stress PPARG GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045165| cell fate commitment PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2 GO:0007507| heart development RXRA;PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0048469| cell maturation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:1904706| PPARG GO:0016525| negative regulation of angiogenesis PPARG;ABCC8 GO:0033189| response to vitamin A PPARG GO:0050872| white fat cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2 GO:0042493| response to drug ABCC8;PPARG GO:0061614| PPARG GO:0030224| monocyte differentiation PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0033993| response to lipid PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction ABCC8;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:1905461| PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development RXRA;PPARG GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;ABCB11;NCOA2;ALB GO:0045600| positive regulation of fat cell differentiation PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0008217| regulation of blood pressure PPARG GO:0031000| response to caffeine PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0007584| response to nutrient PPARG GO:0048511| rhythmic process PPARG;NCOA2 GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound PPARG GO:0006919| activation of caspase activity PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG 7219:[DB07863 DB14010] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;HTR1A;PPARG GO:0007165| signal transduction HTR2A;HTR1A;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0042493| response to drug HTR2A;PPARG GO:0016032| viral reproduction HTR2A;RXRA 7220:[DB07863 DB14509] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007623| circadian rhythm NCOA2;GSK3B GO:0048511| rhythmic process GSK3B;NCOA2;PPARG GO:0007165| signal transduction IMPA2;IMPA1;PPARG 7221:[DB07863 DB00211] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0042493| response to drug PPARG;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRA1D;ADRA1B;ADRA1A GO:0007165| signal transduction ADRA1D;PPARG;ADRA1A;ADRA1B GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A 7222:[DB07863 DB08895] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;JAK2 GO:0045087| innate immune response TYK2;JAK1;JAK3;PPARG;JAK2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;JAK2 GO:0043388| positive regulation of DNA binding PPARG;JAK2 GO:0007165| signal transduction JAK2;PPARG GO:0006919| activation of caspase activity JAK2;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0008285| negative regulation of cell proliferation JAK2;PPARG 7223:[DB07863 DB01324] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01324|Polythiazide SLC12A3 common genes common pathways 7224:[DB07863 DB14539] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0007165| signal transduction NR3C1;PPARG;ANXA1 GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ANXA1;PPARG GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;RXRA GO:0014070| response to organic cyclic compound PPARG;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NR3C1;NCOA2 GO:0045087| innate immune response ANXA1;PPARG GO:0006629| lipid metabolic process CYP11B1;CYP11B2;CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;RXRA;PPARG GO:0043065| positive regulation of apoptotic process ANXA1;PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;NR3C1;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR3C1;PPARG;RXRA GO:0042493| response to drug ABCB1;HSD11B2;ABCG2;ANXA1;PPARG 7225:[DB07863 DB00863] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0007165| signal transduction HRH2;PPARG GO:0007186| G-protein coupled receptor signaling pathway HRH2;PPARG GO:0007584| response to nutrient BCHE;PPARG GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP1A2;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042493| response to drug BCHE;CYP1A2;PPARG;ABCB1 7226:[DB07863 DB05885] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0008217| regulation of blood pressure CACNA1B;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 7227:[DB07863 DB09204] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRB1;ADRA1B;ADRA1D;ADRB2;PPARG GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0007165| signal transduction ADRA1B;ADRB1;ADRA1A;ADRB2;PPARG;ADRA1D GO:0042493| response to drug PPARG;ADRA1A GO:0009409| response to cold ADRB2;PPARG;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP2D6 7228:[DB07863 DB01205] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction PPARG;GABRA6;GABRD;GABRP;GABRE;GABRA5;GABRB1;GABRQ;GABRB3 GO:0042493| response to drug PPARG;GABRG3 7229:[DB07863 DB09185] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0042493| response to drug PPARG;SLC6A2;CYP1A2 7230:[DB07863 DB00285] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A3;ABCG2;SLC6A4;SLC6A2;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP2D6 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 7231:[DB07863 DB00708] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRM1;OPRD1 GO:0007165| signal transduction OPRK1;OPRD1;OPRM1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 7232:[DB07863 DB00390] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1C1;NCOA2;SLC51A;SLCO1B1;RXRA;ABCB11;SLCO1B3;SLCO2B1;SLC51B GO:0008217| regulation of blood pressure PPARG;ATP1A1 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP11A1 GO:0008203| cholesterol metabolic process RXRA;CYP11A1 GO:0042493| response to drug ABCB1;ATP1A1;PPARG 7233:[DB07863 DB00407] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways GO:0007584| response to nutrient PPARG;SERPINC1 7234:[DB07863 DB00822] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0042593| glucose homeostasis PPARG;DBH GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug CYP2E1;PPARG 7235:[DB07863 DB00215] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug PPARG;CYP2E1;SLC6A2;CYP1A2;SLC6A3;SLC6A4;HTR2C;ADRA1A;ABCB1 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP3A4;CYP2D6 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG GO:0010033| response to organic substance CYP1A2;PPARG;SLC6A4 GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0014070| response to organic cyclic compound SLC6A3;PPARG;CYP1A2 GO:0007165| signal transduction HRH1;CHRM1;PPARG;ADRA1A;HTR2C GO:0007186| G-protein coupled receptor signaling pathway CHRM1;PPARG;HRH1;HTR2C;ADRA1A 7236:[DB07863 DB00250] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0010033| response to organic substance PPARG;PTGS2 GO:0007566| embryo implantation PTGS2;RXRA GO:0042493| response to drug PTGS2;CYP2E1;PPARG GO:0006629| lipid metabolic process PTGS2;CYP2C9;PPARG;CYP3A4;PTGS1 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0009612| response to mechanical stimulus PPARG;MPO 7237:[DB07863 DB00980] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007165| signal transduction MTNR1A;PPARG;MTNR1B GO:0042593| glucose homeostasis PPARG;MTNR1B GO:0007186| G-protein coupled receptor signaling pathway MTNR1A;PPARG;MTNR1B GO:0042493| response to drug PPARG;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP1A2 GO:0007623| circadian rhythm MTNR1B;NCOA2;MTNR1A 7238:[DB07863 DB00241] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;PPARG GO:0007165| signal transduction GABRP;GABRD;PPARG;GABRA6;GABRQ;GABRA5;GABRB1;GABRE;CHRNA7;GABRB3;CHRNA4;GRIA2 7239:[DB07863 DB00206] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent BIRC5;RXRA;PPARG;NCOA2 GO:0042493| response to drug PPARG;ABCC2;ABCB1 GO:0006351| transcription, DNA-dependent BIRC5;RXRA;PPARG;NCOA2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;BIRC5 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0015721| bile acid and bile salt transport SLCO2B1;NCOA2;ABCB11;RXRA;SLCO1B1 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 7240:[DB07863 DB01222] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0007165| signal transduction NR3C1;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 GO:0006351| transcription, DNA-dependent PPARG;RXRA;NR3C1;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NR3C1;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NR3C1;NCOA2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR3C1;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR3C1 7241:[DB07863 DB01403] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0042493| response to drug DRD3;HTR2A;PPARG;CYP2E1;ADRA1A;DRD2;DRD1;HTR2C GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;DRD3;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG;DRD2 GO:0008285| negative regulation of cell proliferation PPARG;DRD2;ADRA1A GO:0048511| rhythmic process DRD4;PPARG;NCOA2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0007165| signal transduction CHRM3;HRH1;CHRM5;ADRA1D;ADRA2B;HTR2A;CHRM2;DRD3;PPARG;DRD4;CHRM1;ADRA2C;CHRM4;DRD5;DRD2;ADRA1A;DRD1;ADRA1B;HTR2C;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;DRD3;RXRA GO:0007186| G-protein coupled receptor signaling pathway DRD5;CHRM4;ADRA1A;DRD2;DRD1;HTR2C;ADRA1B;ADRA2A;HRH1;CHRM3;ADRA1D;CHRM5;HTR2A;ADRA2B;DRD3;CHRM2;DRD4;PPARG;ADRA2C;CHRM1 7242:[DB07863 DB14009] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes PPARG common pathways GO:0015909| long-chain fatty acid transport PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0007566| embryo implantation PTGS2;RXRA;SOD1 GO:0019216| regulation of lipid metabolic process HMGCR;NCOA2;CYP1A1;PPARG;CNR1;RXRA GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR55;HTR1A;HTR2A;GPR18;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction OPRM1;CNR2;OPRD1;SMPD1;PPARG;GPR55;HTR1A;GPR12;CNR1;HTR2A;GPR18;PLA2G1B;CACNA1I;CHRNA7 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0033993| response to lipid PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0008217| regulation of blood pressure PTGS1;SOD1;PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance PTGS2;CYP1A2;TRPA1;SOD1;PPARG;CYP1A1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0048511| rhythmic process PPARG;NCOA2;AANAT GO:0007584| response to nutrient CNR1;PPARG;HMGCR GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;RXRA;SOD1 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG GO:1905563| PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0071306| cellular response to vitamin E PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid RXRA;PPARG GO:0048469| cell maturation PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0007623| circadian rhythm AANAT;NCOA2 GO:0008203| cholesterol metabolic process CAT;HMGCR;RXRA GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;CYP2C9;PPARG;PTGS2;CYP1A2;HMGCR GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0045165| cell fate commitment PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;TRPV4;TRPV1 GO:0045087| innate immune response PPARG GO:0007507| heart development PPARG;RXRA GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;PLA2G1B GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;CNR1;SOD1;PTGS2;SMPD1 GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0030224| monocyte differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2 GO:0042493| response to drug SMPD1;ABCC1;CYP1A2;PTGS2;HTR2A;SOD1;TRPA1;PPARG;CYP1A1;ABCG2;CAT GO:1904706| PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0016032| viral reproduction RXRA;HTR2A;VDAC1 GO:0071455| cellular response to hyperoxia PPARG GO:0051289| protein homotetramerization CRYZ;RXRA;TRPA1;TRPV1;TRPM8;CAT 7243:[DB07863 DB11635] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0019216| regulation of lipid metabolic process RXRA;PPARG;ABCA1;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ABCA1;PPARG GO:0001890| placenta development TTPA;PPARG;RXRA GO:0010887| negative regulation of cholesterol storage PPARG;ABCA1 GO:0008217| regulation of blood pressure CYP4F2;PPARG GO:0007584| response to nutrient ABCG8;ABCG5;ABCA1;PPARG;TTPA GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ABCA1 GO:0071300| cellular response to retinoic acid ABCA1;PPARG GO:0006629| lipid metabolic process TTPA;PPARG;CYP3A4;ABCA1;NPC1L1;APOBR GO:0008203| cholesterol metabolic process RXRA;ABCA1;APOBR;NPC1L1 GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;SEC14L2 GO:0016032| viral reproduction RXRA;SCARB1 GO:0071404| cellular response to low-density lipoprotein particle stimulus ABCA1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent SEC14L2;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent SEC14L2;NCOA2;RXRA;PPARG GO:0042493| response to drug PPARG;ABCA1;NPC1L1;ABCG8;ABCB1;ABCG5 7244:[DB07863 DB00837] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GABBR1;PPARG GO:0007165| signal transduction PPARG;GABBR1 7245:[DB07863 DB13620] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0042493| response to drug ATP1A1;PPARG GO:0008217| regulation of blood pressure PPARG;ATP1A1 7246:[DB07863 DB00381] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 GO:0007165| signal transduction PPARG;SMPD1 GO:0043010| camera-type eye development CACNA1C;CYP1A1;RXRA GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0008217| regulation of blood pressure CACNA1B;PPARG GO:0010033| response to organic substance CYP1A1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP2D6 GO:0007507| heart development CACNA1C;PPARG;RXRA GO:0043065| positive regulation of apoptotic process SMPD1;PPARG GO:0042493| response to drug CYP1A1;PPARG;SMPD1;ABCB1 GO:0033189| response to vitamin A CYP1A1;PPARG 7247:[DB07863 DB01173] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;GRIN1 GO:0043065| positive regulation of apoptotic process GRIN1;PPARG GO:0042493| response to drug SLC6A2;CYP1A2;PPARG;CYP2E1 GO:0007186| G-protein coupled receptor signaling pathway HRH1;PPARG GO:0007165| signal transduction PPARG;HRH1 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 7248:[DB07863 DB00915] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;DRD2 GO:0007165| signal transduction PPARG;CHRNA4;CHRNA3;DRD2;CHRNA7 GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0007623| circadian rhythm DDC;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;DRD2 GO:0042493| response to drug DRD2;PPARG;MAOB GO:0032922| circadian regulation of gene expression DRD2;NCOA2 7249:[DB07863 DB00238] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes common pathways GO:0010033| response to organic substance CYP1A2;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4;PPARG;CYP2C9 GO:0042493| response to drug PPARG;CYP1A2 7250:[DB07863 DB00214] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;PTGS1 7251:[DB07863 DB00423] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00423|Methocarbamol CA1 common genes common pathways 7252:[DB07863 DB06726] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRB3;ADRB1;ADRB2;PPARG GO:0007165| signal transduction ADRB3;ADRB1;PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;ADRB2;RXRA GO:0009409| response to cold ADRB1;ADRB3;ADRB2;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6 7253:[DB07863 DB00244] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes PPARG common pathways GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance PPARG;PTGS2;CHUK GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG;PTGS1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0048511| rhythmic process NCOA2;PPARG GO:0007584| response to nutrient PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development RXRA;PPARG GO:0019395| fatty acid oxidation PPARG GO:0045600| positive regulation of fat cell differentiation PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG GO:0007566| embryo implantation RXRA;PTGS2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration PPARG GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0030224| monocyte differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IKBKB;RXRA;CHUK GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0042493| response to drug CHUK;PTGS2;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0033189| response to vitamin A PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG GO:0050872| white fat cell differentiation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0006629| lipid metabolic process PPARG;PTGS2;PTGS1 GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG GO:0007507| heart development RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2 GO:0045087| innate immune response PPARG;IKBKB;CHUK GO:0045165| cell fate commitment PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;MPO GO:0009409| response to cold PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;IKBKB;PPARG;CHUK 7254:[DB07863 DB11274] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0019216| regulation of lipid metabolic process PPARG;DRD3;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway DRD1;DRD2;DRD5;PPARG;DRD3 GO:0007165| signal transduction DRD5;DRD2;DRD1;DRD3;PPARG GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;DRD3;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RXRA;DRD3;PPARG;NCOA2 GO:0042493| response to drug DRD2;DRD1;DRD3;PPARG GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 7255:[DB07863 DB00274] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 7256:[DB07863 DB01352] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007165| signal transduction GABRA6;PPARG;GABRA5;CHRNA7;GRIA2;CHRNA4 7257:[DB07863 DB14185] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;DRD3;NCOA2;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD3 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0007623| circadian rhythm NCOA2;HTR7 GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0042493| response to drug ADRA1A;DRD2;HTR1B;DRD1;HTR2C;DRD3;HTR2A;PPARG GO:0042593| glucose homeostasis ADRA2A;ADRA1B;PPARG GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007165| signal transduction CHRM5;CHRM3;HRH1;HTR1D;DRD4;PPARG;HTR1A;CHRM1;ADRA2C;ADRA2B;HTR2A;CHRM2;DRD3;HTR1E;DRD2;ADRA1A;HTR1B;HTR3A;CHRM4;DRD5;HTR7;ADRA1B;HTR2C;HTR6;ADRA2A;DRD1 GO:0007186| G-protein coupled receptor signaling pathway DRD1;HTR2C;HTR6;ADRA1B;ADRA2A;DRD5;HTR7;CHRM4;HTR1E;HTR1B;DRD2;ADRA1A;HTR2A;ADRA2B;DRD3;CHRM2;HTR1A;DRD4;PPARG;ADRA2C;CHRM1;HRH1;CHRM3;HTR1D;CHRM5 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;DRD3 GO:0045600| positive regulation of fat cell differentiation HTR2C;HTR2A;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0048511| rhythmic process PPARG;DRD4;NCOA2 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 7258:[DB07863 DB00759] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;NCOA2;RXRA GO:0006355| regulation of transcription, DNA-dependent NCOA2;PADI4;PPARG;RXRA GO:0045087| innate immune response PADI4;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006351| transcription, DNA-dependent RXRA;PADI4;PPARG;NCOA2 7259:[DB07863 DB01206] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 7260:[DB07863 DB12001] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0008285| negative regulation of cell proliferation CDK6;PPARG GO:0010033| response to organic substance CDK4;PPARG GO:0031100| organ regeneration CDK4;PPARG GO:0007165| signal transduction CDK4;CDK6;PPARG GO:0032869| cellular response to insulin stimulus CDK4;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;CDK4 GO:0042493| response to drug OTC;ABCG2;ABCB1;PPARG;CDK4 GO:0043065| positive regulation of apoptotic process PPARG;CDK4 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007623| circadian rhythm NCOA2;CDK4 7261:[DB07863 DB01131] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4 GO:0042493| response to drug PPARG;CYP2E1 7262:[DB07863 DB00421] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;ABCC2;SRD5A1 GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0010033| response to organic substance PPARG;SRD5A2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0008217| regulation of blood pressure CYP11B1;PPARG;CACNA1B GO:0015721| bile acid and bile salt transport ABCB11;RXRA;NCOA2;SLCO1A2 GO:0014070| response to organic cyclic compound SRD5A2;PPARG;SRD5A1 GO:0007165| signal transduction PPARG;NR1I2;NR3C1;AR;NR3C2;CACNA1I;PGR GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H;NCOA2;CYP11B1;CYP11B2 GO:0043010| camera-type eye development RXRA;CACNA1C GO:0032869| cellular response to insulin stimulus SRD5A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PGR;NR3C2;AR;NR3C1;NR1I2;RXRA;PPARG GO:0001701| in utero embryonic development RXRA;AR GO:0030522| intracellular receptor mediated signaling pathway AR;NR1I2;NCOA2 GO:0042493| response to drug ABCB1;ABCC2;SRD5A1;SRD5A2;PPARG GO:0006355| regulation of transcription, DNA-dependent PGR;AR;NR3C2;NCOA2;NR3C1;PPARG;RXRA;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;PPARG;RXRA;AR GO:0007507| heart development CACNA1C;PPARG;RXRA GO:0006629| lipid metabolic process CYP11B2;CYP11B1;PPARG;SRD5A2;SRD5A3;SRD5A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;NR1I2;RXRA;PPARG;PGR;AR GO:0043401| steroid hormone mediated signaling pathway PGR;NR3C2;AR;NR3C1;NR1I2;RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;NR3C1;RXRA;NR1I2;PPARG;PGR;AR;NR3C2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR 7263:[DB07863 DB00415] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0007507| heart development TEK;RXRA;PPARG GO:0006629| lipid metabolic process PPARG;SLC16A1 GO:0016525| negative regulation of angiogenesis TEK;PPARG GO:0042593| glucose homeostasis PPARG;SLC16A1 GO:0007165| signal transduction PPARG;TEK GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0043627| response to estrogen stimulus PPARG;TEK GO:0010033| response to organic substance PPARG;TEK 7264:[DB07863 DB00312] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0007165| signal transduction GABRD;PPARG;GABRA6;NR1I2;GABRP;GABRE;GABRQ;GABRB1;GABRA5;GABRB3;CHRNA7;CHRNA4;GRIA2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2 GO:0006351| transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;PPARG;RXRA;NR1I2 GO:0043065| positive regulation of apoptotic process GRIN2A;PPARG;GRIN1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2 GO:0042493| response to drug GABRG3;GRIN2A;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;RXRA 7265:[DB07863 DB09183] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 7266:[DB07863 DB01030] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0048511| rhythmic process PPARG;NCOA2;TOP1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007623| circadian rhythm TOP1;NCOA2 GO:0032922| circadian regulation of gene expression TOP1;NCOA2 GO:0016032| viral reproduction TOP1;RXRA GO:0042493| response to drug ABCB1;ABCG2;TOP1;PPARG 7267:[DB07863 DB01466] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0007584| response to nutrient PPARG;POR GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0019395| fatty acid oxidation POR;PPARG GO:0007165| signal transduction OPRM1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRM1 GO:0042493| response to drug POR;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 7268:[DB07863 DB00568] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0007165| signal transduction CHRM5;CHRM3;HRH1;CHRM1;PPARG;CHRM2;CACNA1I;DRD2;DRD5;CHRM4;DRD1 GO:0043010| camera-type eye development CACNA1C;RXRA;CYP1A1 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0007186| G-protein coupled receptor signaling pathway DRD2;CHRM4;DRD5;DRD1;CHRM5;CHRM3;HRH1;PPARG;CHRM1;CHRM2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;CYP1A1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP2C9;PPARG;CYP1A2 GO:0007507| heart development PPARG;RXRA;CACNA1C GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RXRA;PPARG;NCOA2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0042493| response to drug DRD2;DRD1;CYP1A2;CYP1A1;PPARG 7269:[DB07863 DB01085] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM4;CHRM2;CHRM1;PPARG;CHRM3 GO:0007165| signal transduction CHRM4;CHRM1;PPARG;CHRM2;CHRM3 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;CYP2E1 7270:[DB07863 DB00227] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;PPARG;RXRA GO:0042493| response to drug ABCC2;HDAC2;ABCB1;PPARG;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent HDAC2;NCOA2;PPARG;RXRA GO:0032922| circadian regulation of gene expression NCOA2;HDAC2 GO:0006351| transcription, DNA-dependent HDAC2;NCOA2;RXRA;PPARG GO:0008203| cholesterol metabolic process RXRA;HMGCR GO:0006629| lipid metabolic process HMGCR;PPARG;CYP2C9;CYP3A4;UGT2B7;CYP2D6 GO:0042594| response to starvation PPARG;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC2;PPARG;RXRA;NCOA2 GO:0071300| cellular response to retinoic acid PPARG;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;RXRA;PPARG;NCOA2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0010033| response to organic substance PPARG;UGT1A1 GO:0031000| response to caffeine HDAC2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent HDAC2;NCOA2;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0048511| rhythmic process NCOA2;PPARG;HDAC2 GO:0007584| response to nutrient UGT1A1;HMGCR;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;PPARG GO:0015721| bile acid and bile salt transport NCOA2;SLCO1A2;RXRA;ABCB11;SLCO1B1 GO:0019216| regulation of lipid metabolic process HMGCR;NCOA2;RXRA;PPARG GO:0007165| signal transduction ITGAL;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;ABCC2 GO:0031100| organ regeneration PPARG;UGT1A1 7271:[DB07863 DB00883] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;NPR1 GO:0048662| negative regulation of smooth muscle cell proliferation NPR1;PPARG GO:0008217| regulation of blood pressure PPARG;NPR1 GO:0030308| negative regulation of cell growth NPR1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;CYP2E1 GO:0016525| negative regulation of angiogenesis NPR1;PPARG 7272:[DB07863 DB01033] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0006919| activation of caspase activity PPARG;XDH GO:0014070| response to organic cyclic compound ABCC4;PPARG GO:0010033| response to organic substance PPARG;ABCC4 GO:0032869| cellular response to insulin stimulus PPARG;PPAT GO:0031100| organ regeneration PPAT;PPARG GO:0042493| response to drug PPAT;ABCC4;PPARG GO:0051289| protein homotetramerization HPRT1;PPAT;RXRA;IMPDH2 GO:0007623| circadian rhythm NCOA2;IMPDH2 7273:[DB07863 DB06372] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways GO:0007566| embryo implantation IL1B;RXRA GO:0007165| signal transduction PPARG;IL1B GO:0008285| negative regulation of cell proliferation IL1A;PPARG;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1A;NCOA2;PPARG;RXRA;IL1B GO:0006629| lipid metabolic process PPARG;IL1RN GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL1B 7274:[DB07863 DB08814] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;NFKB1 GO:0007186| G-protein coupled receptor signaling pathway PDE10A;PPARG GO:0007165| signal transduction NFKB1;PDE10A;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;NFKB1 GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;PPARG;RXRA GO:0007623| circadian rhythm NCOA2;NOS2 GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;RXRA;PPARG GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;NFKB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;NCOA2;RXRA;PPARG GO:0045087| innate immune response PPARG;NFKB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process PTGS1;PPARG 7275:[DB07863 DB11619] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GNRHR GO:0007165| signal transduction NR3C1;PPARG;ESR1;PGR;GNRHR;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1;RXRA;AR GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG;ESR1;PGR;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;AR;NR3C1;RXRA;ESR1;PPARG GO:0001701| in utero embryonic development RXRA;AR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1;RXRA;AR GO:0043401| steroid hormone mediated signaling pathway PGR;AR;NR3C1;PPARG;ESR1;RXRA GO:0006351| transcription, DNA-dependent PGR;AR;NR3C1;NCOA2;RXRA;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;ESR1;PPARG;RXRA;NCOA2;NR3C1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RXRA;PPARG;ESR1;NR3C1;NCOA2 7276:[DB07863 DB09272] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PPARG;OPRK1 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0007165| signal transduction OPRK1;PPARG;OPRM1;OPRD1 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B1 GO:0043627| response to estrogen stimulus PPARG;ABCC2;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0042493| response to drug ABCC2;PPARG 7277:[DB07863 DB00294] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0007165| signal transduction PGR;PPARG;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG;RXRA;PGR GO:0006351| transcription, DNA-dependent NCOA2;PPARG;ESR1;RXRA;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ESR1;PPARG;NCOA2;PGR GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1;RXRA GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;ESR1;PGR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;ESR1;PPARG;PGR 7278:[DB07863 DB00657] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0007165| signal transduction PPARG;CHRNB2;CHRNA7;CHRNA4;CHRNA2 7279:[DB07863 DB01182] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0009409| response to cold ADRB1;ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2;CYP2D6 GO:0042493| response to drug ABCB1;PPARG;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2;ADRB1 GO:0007165| signal transduction PPARG;ADRB2;ADRB1 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG 7280:[DB07863 DB00810] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM1;PPARG GO:0007165| signal transduction CHRM1;PPARG;CHRNA2 GO:0006629| lipid metabolic process CYP2D6;PPARG 7281:[DB07863 DB01018] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007165| signal transduction ADRA2A;PPARG;ADRA2B GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;ADRA2B;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7282:[DB07863 DB05361] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0007584| response to nutrient PPARG;SERPINC1 GO:0008285| negative regulation of cell proliferation F2R;PPARG GO:0006919| activation of caspase activity PPARG;F2R GO:0007165| signal transduction PPARG;F2R GO:0007186| G-protein coupled receptor signaling pathway F2R;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;F2R 7283:[DB07863 DB01409] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway CHRM4;CHRM1;PPARG;CHRM2;CHRM5;CHRM3 GO:0007165| signal transduction CHRM4;CHRM2;CHRM1;PPARG;CHRM3;CHRM5 7284:[DB07863 DB00812] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0007566| embryo implantation PTGS2;RXRA;PTGIS GO:0042493| response to drug PTGS2;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;PTGS2;PTGIS;PTGS1 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 7285:[DB07863 DB00865] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0007165| signal transduction PPARG;ADRA2A;ADRA1A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRA1A;ADRA2A GO:0007584| response to nutrient POR;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0019395| fatty acid oxidation PPARG;POR GO:0014070| response to organic cyclic compound SLC6A3;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug SLC6A3;ADRA1A;POR;PPARG 7286:[DB07863 DB13941] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 7287:[DB07863 DB00764] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;RXRA;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;NR3C1;NCOA2;RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;NR3C1;RXRA;PPARG;PGR GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA;PGR GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG;PGR GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;NR3C1;PGR GO:0007165| signal transduction PGR;PPARG;NR3C1 7288:[DB07863 DB00694] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;TOP2A;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;RXRA;NCOA2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0042493| response to drug ABCC2;ABCG2;POR;ABCB1;CYP1A1;PPARG;ABCC6;ABCC1 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG GO:0010033| response to organic substance CYP1A1;PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0007584| response to nutrient PPARG;POR GO:0048511| rhythmic process NCOA2;PPARG;TOP2A GO:0019395| fatty acid oxidation POR;PPARG GO:0015721| bile acid and bile salt transport ABCB11;RXRA;NCOA2 GO:0006919| activation of caspase activity PPARG;XDH GO:0014070| response to organic cyclic compound CYP1A1;PPARG 7289:[DB07863 DB00189] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRB3;GABRD;GABRA6;PPARG;GABRP;GABRE;GABRQ;GABRA5;GABRB1 GO:0042493| response to drug GABRG3;PPARG 7290:[DB07863 DB01366] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01366|Procaterol ADRB2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG GO:0007165| signal transduction ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0009409| response to cold ADRB2;PPARG 7291:[DB07863 DB08874] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCB1 7292:[DB07863 DB13036] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13036|Ramatroban PTGDR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;PTGDR2 GO:0007165| signal transduction PPARG;PTGDR2 7293:[DB07863 DB01144] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways GO:0010033| response to organic substance CA2;PPARG GO:0043627| response to estrogen stimulus CA2;PPARG 7294:[DB07863 DB01623] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0007165| signal transduction HTR2A;PPARG;DRD2;DRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;HTR2A;DRD1;DRD2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2D6 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0042493| response to drug DRD2;DRD1;CYP1A2;PPARG;HTR2A 7295:[DB07863 DB00857] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0010033| response to organic substance PPARG;CYP1A2;SQLE GO:0008203| cholesterol metabolic process RXRA;CYP11A1;SQLE GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PTGS1;CYP2D6;CYP1A2;CYP11A1;CYP3A4;PPARG;CYP2C9 GO:0042493| response to drug CYP1A2;PPARG 7296:[DB07863 DB13997] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 7297:[DB07863 DB00691] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure PPARG;ACE GO:0016032| viral reproduction RXRA;ACE2 7298:[DB07863 DB09060] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0042493| response to drug PPARG;ABCC2 7299:[DB07863 DB00949] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG;GRIN2A GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9 GO:0043065| positive regulation of apoptotic process PPARG;GRIN2A 7300:[DB07863 DB08912] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;PPARG GO:0007507| heart development RAF1;RXRA;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;NCOA2;RXRA;PPARG GO:0048511| rhythmic process SIK1;NCOA2;PPARG GO:0008285| negative regulation of cell proliferation RAF1;PPARG GO:0015721| bile acid and bile salt transport NCOA2;SLCO1B1;RXRA;SLCO1B3 GO:0007165| signal transduction BRAF;LIMK1;RAF1;PPARG GO:0032870| cellular response to hormone stimulus SIK1;NCOA2 7301:[DB07863 DB00347] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9 GO:0042493| response to drug PPARG;CYP2E1 7302:[DB07863 DB11755] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0007584| response to nutrient PPARG;CNR1 GO:0010033| response to organic substance TRPA1;PPARG GO:0014070| response to organic cyclic compound PPARG;TRPA1 GO:0007165| signal transduction CNR2;HTR1A;PPARG;GPR55;CNR1 GO:0042593| glucose homeostasis PPARG;CNR1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;CNR1;HTR1A;PPARG;GPR55 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;CNR1 GO:0051289| protein homotetramerization TRPM8;RXRA;TRPA1 GO:0042493| response to drug PPARG;TRPA1 GO:0043065| positive regulation of apoptotic process PPARG;CNR1 GO:0009409| response to cold TRPM8;PPARG;TRPA1 7303:[DB07863 DB00378] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;PGR GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;PGR GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RXRA;PPARG;NCOA2 GO:0006355| regulation of transcription, DNA-dependent PGR;NCOA2;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;PGR GO:0007165| signal transduction PPARG;PGR 7304:[DB07863 DB08918] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 GO:0042493| response to drug SLC6A4;ABCB1;PPARG;SLC6A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007623| circadian rhythm NCOA2;SLC6A4 7305:[DB07863 DB01170] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;SLC6A2 GO:0006629| lipid metabolic process CYP3A4;PPARG 7306:[DB07863 DB00029] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007165| signal transduction PPARG;FGA;PLAUR GO:0043388| positive regulation of DNA binding PPARG;PLAUR GO:0008285| negative regulation of cell proliferation PLG;PPARG GO:0007623| circadian rhythm NCOA2;SERPINE1 GO:0045087| innate immune response PPARG;FGA GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;NCOA2;PPARG;RXRA 7307:[DB07863 DB01129] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug ABCG2;CYP1A2;CYP1A1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 7308:[DB07863 DB06589] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;PDGFRB GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0033993| response to lipid PDGFRB;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction SH2B3;KIT;ITK;PPARG;FGF1;PDGFRB GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;PPARG;PDGFRB GO:0015721| bile acid and bile salt transport RXRA;SLCO1B1;NCOA2 GO:0010033| response to organic substance PPARG;UGT1A1;CYP1A2 GO:0043627| response to estrogen stimulus PDGFRB;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;KIT GO:0032526| response to retinoic acid PPARG;PDGFRB;RXRA GO:0043065| positive regulation of apoptotic process PDGFRB;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;FGF1;PPARG GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2D6 GO:0042594| response to starvation UGT1A1;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0045087| innate immune response ITK;PPARG GO:0042493| response to drug PPARG;UGT1A1;CYP1A2;ABCG2;ABCB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;KIT GO:0016032| viral reproduction RXRA;KDR;PDGFRA 7309:[DB07863 DB00698] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 GO:0019395| fatty acid oxidation PPARG;POR GO:0007584| response to nutrient POR;PPARG GO:0042493| response to drug PPARG;POR;ABCG2 7310:[DB07863 DB01261] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 7311:[DB07863 DB01108] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR2;ESR1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;ESR1;ESR2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;RXRA;PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR2;RXRA;ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR2;RXRA;PPARG;ESR1;NCOA2 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;NCOA2;RXRA;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;NCOA2;ESR1;PPARG;RXRA GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007165| signal transduction ESR2;ESR1;PPARG 7312:[DB07863 DB04861] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0007165| signal transduction ADRB2;PPARG;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ADRB2;RXRA;PPARG GO:0009409| response to cold ADRB1;PPARG;ADRB2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG 7313:[DB07863 DB06733] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 7314:[DB07863 DB02056] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;PPARG;AKR1C3 GO:0007165| signal transduction PTGDR2;PPARG GO:0007584| response to nutrient AKR1C3;PPARG GO:0071379| cellular response to prostaglandin stimulus AKR1C3;PPARG 7315:[DB07863 DB01294] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 7316:[DB07863 DB04821] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0010033| response to organic substance SLC6A4;PPARG GO:0007584| response to nutrient PPARG;SLC6A4 GO:0042493| response to drug SLC6A4;SLC6A3;MAOB;SLC6A2;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0009612| response to mechanical stimulus MPO;PPARG 7317:[DB07863 DB00193] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0042493| response to drug HTR2C;SLC6A4;PPARG;UGT1A1;SLC6A2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1;OPRD1;CHRM3;OPRM1;OPRK1;HTR2C GO:0007165| signal transduction HTR2C;CHRNA7;OPRK1;PPARG;CHRM1;OPRM1;OPRD1;CHRM3 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0010033| response to organic substance SLC6A4;UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0007584| response to nutrient SLC6A4;PPARG;UGT1A1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C 7318:[DB07863 DB01022] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 7319:[DB07863 DB00611] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0007165| signal transduction OPRK1;PPARG;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 7320:[DB07863 DB00726] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00726|Trimipramine SLC6A4;SLC6A2;SLC6A3;HTR2A;HTR1A;ADRA1A;ADRA1B;DRD2;ADRA2B;HRH1;HTR2C;HTR3A;HTR1D;ADRA2A;DRD1;DRD5;ADRB1;ADRB2;ADRB3;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2C;HTR2A;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2;ADRA1A GO:0010033| response to organic substance SLC6A4;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0007186| G-protein coupled receptor signaling pathway DRD5;CHRM4;ADRB1;ADRA1A;DRD2;DRD1;ADRB3;HTR2C;ADRA1B;ADRA2A;HTR1D;CHRM3;HRH1;CHRM5;HTR2A;ADRB2;ADRA2B;CHRM2;HTR1A;PPARG;CHRM1 GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0007165| signal transduction CHRM1;HTR1A;PPARG;CHRM2;HTR2A;ADRA2B;ADRB2;CHRM5;CHRM3;HRH1;HTR1D;ADRA2A;HTR2C;ADRA1B;ADRB3;DRD1;ADRB1;DRD2;ADRA1A;DRD5;HTR3A;CHRM4 GO:0042493| response to drug ABCB1;DRD2;ADRA1A;SLC6A4;HTR2C;SLC6A3;DRD1;SLC6A2;PPARG;HTR2A GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0009409| response to cold ADRB1;ADRB3;ADRB2;PPARG GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;ADRB2;RXRA;DRD2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;CYP2D6 7321:[DB07863 DB00745] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0042493| response to drug CYP1A2;PPARG;SLC6A3 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound SLC6A3;PPARG;CYP1A2 GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0007165| signal transduction ADRA1B;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;PPARG 7322:[DB07863 DB06770] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0042493| response to drug PPARG;CYP1A1;CYP2E1;CYP1A2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2D6 7323:[DB07863 DB01234] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0007165| signal transduction PPARG;NR1I2;NR3C1;ANXA1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ANXA1;PPARG GO:0019216| regulation of lipid metabolic process CYP4A11;NCOA2;CYP1A1;PPARG;RXRA GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0045892| negative regulation of transcription, DNA-dependent NR0B1;PPARG;NR1I2;NCOA2 GO:0010033| response to organic substance CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;SLCO1A2;NCOA2 GO:0014070| response to organic cyclic compound ANXA1;PPARG;CYP1A1 GO:0045087| innate immune response ANXA1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR0B1;PPARG;RXRA;NCOA2;NR3C1 GO:0035902| response to immobilization stress PPARG;CYP1A1;NR0B1 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP11A1;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;PPARG;RXRA;NR1I2 GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1;ANXA1 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;RXRA;NR3C1;NCOA2;NR0B1 GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1I2;PPARG;NR3C1;NR0B1 GO:0008203| cholesterol metabolic process RXRA;CYP11A1 GO:0007623| circadian rhythm NOS2;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;NR1I2;PPARG;NR3C1;NR0B1 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0030522| intracellular receptor mediated signaling pathway NR0B1;NR1I2;NCOA2 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA;NR3C1;NCOA2;NR0B1 GO:0042493| response to drug ABCC2;ABCG2;ANXA1;ABCB1;PPARG;CYP1A1;CYP2E1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;NR1I2;PPARG 7324:[DB07863 DB01016] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes common pathways GO:0071404| cellular response to low-density lipoprotein particle stimulus ABCA1;PPARG GO:0016525| negative regulation of angiogenesis ABCC8;PPARG GO:0042493| response to drug ABCC2;ABCG2;CPT1A;ABCB1;ABCC9;ABCC8;PPARG;KCNJ11;ABCC1;ABCA1 GO:0071300| cellular response to retinoic acid PPARG;ABCA1 GO:0007507| heart development KCNJ8;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;ABCA1;CPT1A GO:0008203| cholesterol metabolic process ABCA1;RXRA GO:0007623| circadian rhythm CPT1A;NCOA2 GO:0010887| negative regulation of cholesterol storage ABCA1;PPARG GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;RXRA;ABCB11;NCOA2;ABCC3;SLCO1A2 GO:0007584| response to nutrient ABCA1;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ABCA1 GO:0014070| response to organic cyclic compound CPT1A;PPARG GO:0030855| epithelial cell differentiation PPARG;CPT1A GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0007165| signal transduction PPARG;ABCC9;ABCC8 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ABCA1 GO:0019216| regulation of lipid metabolic process CPT1A;NCOA2;ABCA1;PPARG;RXRA 7325:[DB07863 DB05928] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;RXRA GO:0006351| transcription, DNA-dependent NCOA2;NR1I2;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;NR1I2;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP1A2;UGT2B7 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042493| response to drug ABCG2;ABCB1;PPARG;CYP1A1;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2;RXRA GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;RXRA GO:0033189| response to vitamin A CYP1A1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007165| signal transduction NR1I2;PPARG GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0015721| bile acid and bile salt transport SLCO2B1;SLCO1B1;RXRA;SLCO1B3;ABCC3;NCOA2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG 7326:[DB07863 DB13952] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes NCOA2 common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1B3;RXRA;SLCO1B1;NCOA2;SLCO1A2;SLCO1C1 GO:0001890| placenta development PPARG;RXRA;HSD17B2 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:1904017| NCOA2 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;NCOA2 GO:0008285| negative regulation of cell proliferation GPER1;CYP1B1;BECN1;PPARG GO:0010033| response to organic substance CYP1A1;PPARG;UGT1A1;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;UGT1A1;CYP1A2 GO:0045475| locomotor rhythm NCOA2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction ESR2;CHRNA4;GPER1;ESR1;PPARG;NR1I2 GO:0007186| G-protein coupled receptor signaling pathway GPER1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0032922| circadian regulation of gene expression NCOA2 GO:0016032| viral reproduction RXRA;BECN1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0010906| regulation of glucose metabolic process NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG;ESR1;ESRRG;ESR2 GO:0001701| in utero embryonic development RXRA;HSD17B2 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:1904706| PPARG;GPER1 GO:0042493| response to drug CYP1A2;UGT1A1;BECN1;CYP1A1;PPARG;ABCB1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1;NR1I2;RXRA;ESRRG;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;RXRA;NR1I2;ESRRG;ESR2 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RXRA GO:0043065| positive regulation of apoptotic process CYP1B1;GPER1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESRRG;GPER1;NR1I2;RXRA;PPARG;ESR1;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;NCOA2;RXRA;ESR1;PPARG GO:0045087| innate immune response PPARG;GPER1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process HSD17B2;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0007623| circadian rhythm NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0032526| response to retinoic acid PPARG;RXRA;HSD17B2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RXRA;PPARG;ESR1;ESR2;ESRRG;GPER1 GO:0006351| transcription, DNA-dependent ESRRG;ESR2;NCOA2;PPARG;ESR1;NR1I2;RXRA 7327:[DB07863 DB06704] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06704|Iobenguane SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;PPARG 7328:[DB07863 DB00439] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug PPARG;UGT1A1;ABCC2;ABCG2;ABCB1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;HMGCR;CYP2D6 GO:0008203| cholesterol metabolic process HMGCR;RXRA GO:0010033| response to organic substance PPARG;UGT1A1 GO:0007584| response to nutrient HMGCR;UGT1A1;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;SLCO1B1;NCOA2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1;NCOA2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;HMGCR;RXRA;PPARG 7329:[DB07863 DB00593] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 GO:0006629| lipid metabolic process PPARG;CYP3A4 7330:[DB07863 DB00508] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD2 GO:0007507| heart development HTR2B;PPARG;RXRA GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0042493| response to drug PPARG;BCHE;DRD1;HTR2B;ABCB1;DRD2 GO:0007165| signal transduction CHRM2;CHRM1;PPARG;DRD1;HTR2B;DRD2 GO:0007186| G-protein coupled receptor signaling pathway HTR2B;DRD1;DRD2;CHRM1;PPARG;CHRM2 GO:0008285| negative regulation of cell proliferation DRD2;BCHE;PPARG GO:0007584| response to nutrient BCHE;PPARG 7331:[DB07863 DB00486] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG GO:0043065| positive regulation of apoptotic process PPARG;CNR1 GO:0007584| response to nutrient CNR1;PPARG GO:0007165| signal transduction PPARG;CNR1;CNR2 GO:0042593| glucose homeostasis CNR1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CNR1;RXRA GO:0007186| G-protein coupled receptor signaling pathway CNR2;PPARG;CNR1 7332:[DB07863 DB05120] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05120|AT1391 INSR common genes common pathways GO:0032869| cellular response to insulin stimulus INSR;PPARG GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG GO:0042593| glucose homeostasis INSR;PPARG GO:0006355| regulation of transcription, DNA-dependent INSR;NCOA2;RXRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent INSR;RXRA;PPARG 7333:[DB07863 DB00198] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0030855| epithelial cell differentiation CES1;PPARG GO:0014070| response to organic cyclic compound ABCC4;PPARG GO:0010033| response to organic substance ABCC4;PPARG GO:0006629| lipid metabolic process NEU1;PPARG;NEU2 GO:0042493| response to drug PPARG;ABCC4 7334:[DB07863 DB00188] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042493| response to drug PPARG;CYP1A2 GO:0016032| viral reproduction RXRA;PSMB1;PSMB5 7335:[DB07863 DB08871] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0042493| response to drug PPARG;BCL2 GO:0008285| negative regulation of cell proliferation BCL2;PPARG 7336:[DB07863 DB00304] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;RXRA;NCOA2;PGR GO:0045893| positive regulation of transcription, DNA-dependent RXRA;ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RXRA;ESR1;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1;RXRA;PGR GO:0006351| transcription, DNA-dependent PGR;ESR1;PPARG;RXRA;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;ESR1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ESR1;RXRA;NCOA2;PGR GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007165| signal transduction ESR1;PPARG;PGR 7337:[DB07863 DB09223] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;DRD3;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug DRD2;HTR2A;DRD3;PPARG GO:0007165| signal transduction DRD3;HTR2A;PPARG;DRD2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;DRD3;PPARG;DRD2 GO:0019216| regulation of lipid metabolic process NCOA2;DRD3;RXRA;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008285| negative regulation of cell proliferation PPARG;DRD2 7338:[DB07863 DB09285] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0010033| response to organic substance PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0007584| response to nutrient TBXA2R;PPARG GO:0007566| embryo implantation RXRA;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway LTB4R;PPARG;TBXA2R GO:0007165| signal transduction PPARG;LTB4R;TBXA2R GO:0042493| response to drug PTGS2;PPARG;TBXA2R GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 7339:[DB07863 DB01174] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01174|Phenobarbital GABRA1;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP2C19;CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2;CYP2A6;CYP2E1;CYP3A5;CYP4A11;CYP1A1;CYP1B1;CYP2C18;CYP3A7;CYP4B1;UGT1A1;UGT2B7;ABCB1;ABCC3;ABCB11;ABCC1;SLCO2A1;ABCC2 common genes common pathways GO:0006351| transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RXRA;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process UGT2B7;CYP2C9;PPARG;CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;PPARG;RXRA;NR1I2 GO:0043065| positive regulation of apoptotic process PPARG;GRIN1;GRIN2A;CYP1B1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2 GO:0042493| response to drug CYP1A2;UGT1A1;ABCC1;CYP1A1;PPARG;CYP2E1;ABCB1;GRIN2A;ABCC2 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;RXRA GO:0033189| response to vitamin A CYP1A1;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;CYP4A11;NCOA2 GO:0007165| signal transduction CHRNA7;GRIA2;CHRNA4;PPARG;NR1I2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2;ABCC2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0010033| response to organic substance CYP1A1;PPARG;CYP1A2;UGT1A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2;ABCC3 7340:[DB07863 DB11251] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0001890| placenta development RXRA;TTPA;PPARG GO:0008217| regulation of blood pressure PPARG;CYP4F2 GO:0007584| response to nutrient PPARG;TTPA GO:0007165| signal transduction VLDLR;PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;LDLR GO:0016032| viral reproduction SCARB1;LDLR;RXRA GO:0045893| positive regulation of transcription, DNA-dependent SEC14L2;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent SEC14L2;PPARG;RXRA;NCOA2 GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process APOBR;LDLR;CYP3A4;PPARG;TTPA;VLDLR GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;VLDLR;PPARG GO:0008203| cholesterol metabolic process APOBR;LDLR;RXRA;VLDLR GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;SEC14L2 7341:[DB07863 DB00973] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;ABCC2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction ANPEP;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;SLCO1B1;NCOA2;ABCC3 GO:0010033| response to organic substance UGT1A1;PPARG GO:0008217| regulation of blood pressure ANPEP;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient ABCG8;ABCG5;PPARG;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process UGT2B7;NPC1L1;SOAT1;CYP3A4;PPARG GO:0008203| cholesterol metabolic process SOAT1;RXRA;NPC1L1 GO:0016032| viral reproduction RXRA;ANPEP GO:0010742| macrophage derived foam cell differentiation SOAT1;PPARG GO:0042493| response to drug PPARG;UGT1A1;NPC1L1;ABCG2;ABCC2;ABCB1;ABCG5;ABCG8 7342:[DB07863 DB01577] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0042493| response to drug SLC6A4;SLC6A3;MAOB;SLC6A2;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;PPARG;ADRA2C;ADRA2B;TAAR1 GO:0007165| signal transduction ADRA2A;TAAR1;ADRA2B;ADRA2C;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0010033| response to organic substance SLC6A4;PPARG GO:0007584| response to nutrient SLC6A4;PPARG 7343:[DB07863 DB09330] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0033993| response to lipid PPARG;EGFR GO:0007165| signal transduction EGFR;PPARG GO:0014070| response to organic cyclic compound EGFR;CYP1A2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0007623| circadian rhythm NCOA2;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;EGFR GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042493| response to drug CYP1A2;PPARG;ABCB1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;RXRA;PPARG 7344:[DB07863 DB05740] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0007165| signal transduction CHRNA7;CHRNA10;CHRNA2;CHRNA4;PPARG;CHRNA9;CHRNB2 7345:[DB07863 DB00473] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 7346:[DB07863 DB00441] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0014070| response to organic cyclic compound TYMS;PPARG GO:0042493| response to drug ABCB1;PPARG;TYMS GO:0033189| response to vitamin A TYMS;PPARG GO:0051289| protein homotetramerization CDA;RXRA GO:0030308| negative regulation of cell growth PPARG;CDA GO:0007623| circadian rhythm NCOA2;TYMS 7347:[DB07863 DB00540] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0042493| response to drug HTR2A;PPARG;CYP2E1;SLC6A2;CYP1A2;HTR2C;SLC6A4;ADRA1A;DRD2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP3A4;PTGS1;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0009409| response to cold PPARG;ADRB2;ADRB1;ADRB3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ADRB2;NCOA2;DRD2 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2;SLC6A4 GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0007165| signal transduction ADRA1D;CHRM5;CHRM3;HRH1;HTR1A;PPARG;ADRA2C;CHRM1;HTR2A;ADRB2;ADRA2B;CHRM2;ADRB1;ADRA1A;DRD2;CHRM4;HTR6;HTR2C;ADRA1B;ADRA2A;ADRB3 GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRB3;ADRA2A;ADRA1B;HTR6;HTR2C;CHRM4;ADRA1A;DRD2;ADRB1;CHRM2;ADRB2;ADRA2B;HTR2A;CHRM1;ADRA2C;PPARG;HTR1A;HRH1;CHRM3;ADRA1D;CHRM5 7348:[DB07863 DB05015] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;HDAC9;HDAC5 GO:0019216| regulation of lipid metabolic process HDAC3;NCOA2;PPARG;RXRA GO:0008285| negative regulation of cell proliferation HDAC1;HDAC4;PPARG GO:0010033| response to organic substance CYP1A2;PPARG;HDAC6 GO:0045892| negative regulation of transcription, DNA-dependent HDAC1;PPARG;HDAC4;HDAC6;HDAC7;NCOA2;HDAC3;HDAC9;HDAC2;HDAC5;HDAC10 GO:0031000| response to caffeine HDAC1;PPARG;HDAC2 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC1;HDAC2 GO:0048511| rhythmic process HDAC2;HDAC1;PPARG;NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;CYP2C9;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC10;HDAC8;HDAC2;HDAC5;HDAC9;HDAC3;HDAC7;NCOA2;PPARG;HDAC4;HDAC1;RXRA GO:0007507| heart development RXRA;PPARG;HDAC9 GO:0071300| cellular response to retinoic acid HDAC2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC5;HDAC2;HDAC3;NCOA2;PPARG;HDAC4;RXRA;HDAC1 GO:0045598| regulation of fat cell differentiation PPARG;HDAC6 GO:0006351| transcription, DNA-dependent HDAC10;HDAC9;HDAC3;HDAC5;HDAC2;HDAC8;HDAC11;NCOA2;HDAC7;RXRA;HDAC1;HDAC6;PPARG;HDAC4 GO:0007623| circadian rhythm HDAC3;NCOA2 GO:0016032| viral reproduction HDAC1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;PPARG;HDAC5 GO:0032922| circadian regulation of gene expression HDAC2;NCOA2;HDAC1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC4;PPARG;RXRA;HDAC1;HDAC2 GO:0042493| response to drug HDAC2;HDAC5;ABCB1;HDAC1;PPARG;HDAC4;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent HDAC7;NCOA2;HDAC11;HDAC4;PPARG;HDAC6;HDAC1;RXRA;HDAC10;HDAC2;HDAC8;HDAC5;HDAC9;HDAC3 7349:[DB07863 DB01396] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways GO:0008217| regulation of blood pressure ATP1A1;PPARG GO:0015721| bile acid and bile salt transport RXRA;SLCO1A2;NCOA2;ALB GO:0042493| response to drug ATP1A1;PPARG;ABCB1 GO:0006629| lipid metabolic process CYP11A1;PPARG;CYP3A4 GO:0008203| cholesterol metabolic process CYP11A1;RXRA 7350:[DB07863 DB00404] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:0007165| signal transduction GABRE;GABRQ;GABRB1;GABRA5;GABRD;GABRA6;PPARG;GABRP;GABRB3 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG GO:0042493| response to drug GABRG3;PPARG 7351:[DB07863 DB01407] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ADRB2;TNF;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process TNF;NGF;PPARG GO:0009409| response to cold ADRB3;ADRB1;PPARG;ADRB2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TNF;RXRA GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG;NCOA2 GO:0010033| response to organic substance TNF;PPARG;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0006919| activation of caspase activity TNF;NGF;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction ADRB3;ADRB1;ADRB2;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2;ADRB3;ADRB1 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1 GO:0045994| positive regulation of translational initiation by iron RXRA;TNF 7352:[DB07863 DB01439] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007165| signal transduction OPRK1;OPRM1;OPRD1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRM1;OPRD1;OPRK1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG 7353:[DB07863 DB00072] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;ERBB2 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;RXRA;PPARG GO:0016032| viral reproduction RXRA;FCGR2B GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;EGFR;PPARG;RXRA GO:0007623| circadian rhythm NCOA2;EGFR GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;ERBB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;EGFR GO:0007507| heart development ERBB2;RXRA;PPARG GO:0045087| innate immune response PPARG;C1S;C1QC;C1R;C1QB;FCGR1A;C1QA GO:0014070| response to organic cyclic compound EGFR;PPARG GO:0033993| response to lipid PPARG;EGFR GO:0007165| signal transduction FCGR2C;PPARG;FCGR2B;EGFR;FCGR1A;ERBB2 7354:[DB07863 DB00959] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0007165| signal transduction PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;RXRA;NR3C1;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;RXRA;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NR3C1;NCOA2 GO:0042493| response to drug ABCB1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C1 7355:[DB07863 DB01411] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0010033| response to organic substance PPARG;TNF GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF;NCOA2;NFKB1 GO:0006919| activation of caspase activity TNF;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007165| signal transduction PPARG;CYSLTR1;NFKB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CYSLTR1 GO:0045994| positive regulation of translational initiation by iron TNF;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL5;TNF;PPARG GO:0042493| response to drug ABCC2;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;NFKB1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;RXRA;PPARG;NFKB1;IL5 GO:0043065| positive regulation of apoptotic process TNF;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;TNF;RXRA;PPARG;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;TNF;PPARG;NFKB1 GO:0045087| innate immune response NFKB1;PPARG;RNASE3 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NFKB1 GO:0006351| transcription, DNA-dependent NFKB1;PPARG;RXRA;NCOA2 7356:[DB07863 DB00041] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PLA2G4A;PPARG;CYP3A4 GO:0042493| response to drug PTGS2;CYP2E1;PPARG GO:0016032| viral reproduction IL2RG;IL2RB;RXRA GO:0007566| embryo implantation RXRA;PTGS2 GO:0007165| signal transduction IL2RG;IL2RB;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0006919| activation of caspase activity XDH;PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0010033| response to organic substance PPARG;PTGS2 7357:[DB07863 DB09555] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;HRH1 GO:0007165| signal transduction HRH1;PPARG 7358:[DB07863 DB00379] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;AHR GO:0042493| response to drug PPARG;CYP2E1;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;AHR GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AHR GO:0032922| circadian regulation of gene expression NCOA2;AHR GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;RXRA;PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;AHR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;AHR GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent AHR;NCOA2;PPARG GO:0048511| rhythmic process NCOA2;AHR;PPARG 7359:[DB07863 DB09418] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA 7360:[DB07863 DB00526] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0043065| positive regulation of apoptotic process SOD1;PPARG;CYP1B1 GO:0009612| response to mechanical stimulus MPO;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0042493| response to drug ABCG2;ABCC2;CYP2E1;CYP1A1;PPARG;SOD1 GO:0001701| in utero embryonic development RXRA;ATP7A GO:0033189| response to vitamin A CYP1A1;PPARG GO:1904706| PPARG;GSTP1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 GO:0007566| embryo implantation RXRA;SOD1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;NQO1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0001890| placenta development RXRA;SOD1;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient NQO1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1;SOD1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1 GO:0008217| regulation of blood pressure PPARG;SOD1 7361:[DB07863 DB01127] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;RXRA;NR1I2;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;NR1I2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2 GO:0042493| response to drug CYP2E1;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;NR1I2;PPARG GO:0007165| signal transduction PPARG;NR1I2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2 7362:[DB07863 DB00195] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2D6 GO:0009409| response to cold ADRB2;PPARG;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ADRB2;RXRA;NCOA2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007165| signal transduction PPARG;ADRB2;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2;ADRB1 7363:[DB07863 DB09288] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes common pathways GO:0051289| protein homotetramerization TRPV1;RXRA GO:0042493| response to drug CYP2E1;PPARG;CYP1A2;UGT1A1;BCHE;PTGS2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;SULT1A3;SULT2A1;SULT1A1;TRPV1;PTGS1;CYP3A4;PPARG;CYP2C9;PTGS2;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;TRPV1 GO:0043065| positive regulation of apoptotic process TRPV1;PTGS2;PPARG;CNR1 GO:0010033| response to organic substance CYP1A2;UGT1A1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2;BCHE GO:0008217| regulation of blood pressure PPARG;PTGS2;PTGS1 GO:0007584| response to nutrient CNR1;PPARG;BCHE;UGT1A1 GO:0045600| positive regulation of fat cell differentiation SULT1E1;PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;UGT1A1;PPARG GO:0007165| signal transduction CNR1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0042593| glucose homeostasis PPARG;CNR1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0019216| regulation of lipid metabolic process PPARG;CNR1;RXRA;UGT1A9;NCOA2;SULT2A1 GO:0007566| embryo implantation RXRA;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway CNR1;PPARG 7364:[DB07863 DB01363] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance PPARG;SLC6A4 GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007165| signal transduction ADRA2B;ADRB2;ADRA2C;PPARG;ADRB3;ADRA2A;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRA2C;ADRB2;ADRA2B;ADRA2A;ADRB3;ADRB1 GO:0042493| response to drug SLC6A4;SLC6A3;PPARG;MAOB;SLC6A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ADRB2;RXRA;NCOA2 GO:0009409| response to cold ADRB3;ADRB1;ADRB2;PPARG GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 7365:[DB07863 DB14540] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;RXRA;NR3C1;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;PPARG;RXRA GO:0045087| innate immune response ANXA1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP11B1;CYP11B2 GO:0043065| positive regulation of apoptotic process ANXA1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;PPARG;RXRA GO:0042493| response to drug PPARG;ABCB1;HSD11B2;ANXA1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NR3C1;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;ANXA1 GO:0007165| signal transduction PPARG;NR3C1;ANXA1 GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0014070| response to organic cyclic compound ANXA1;PPARG GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1A2 7366:[DB07863 DB13953] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes NCOA2 common pathways GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0007623| circadian rhythm NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway GPER1;ESRRG;ESR2;ESR1;PPARG;RXRA;NR1I2 GO:0006351| transcription, DNA-dependent ESRRG;ESR2;NCOA2;ESR1;PPARG;RXRA;NR1I2 GO:0032526| response to retinoic acid PPARG;RXRA;HSD17B2 GO:0043065| positive regulation of apoptotic process CYP1B1;GPER1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;GPER1;ESRRG;ESR1;PPARG;RXRA;NR1I2;NCOA2 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;HSD17B2;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;NCOA2;RXRA;PPARG;ESR1 GO:0045087| innate immune response GPER1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;ESR1;ESR2;ESRRG GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;BECN1;CYP1A2;PPARG;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1;NR1I2;RXRA;ESRRG;ESR2 GO:0048384| retinoic acid receptor signaling pathway RXRA;ESRRG GO:0016032| viral reproduction RXRA;BECN1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0010906| regulation of glucose metabolic process NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0032922| circadian regulation of gene expression NCOA2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0033189| response to vitamin A CYP1A1;PPARG GO:1904706| GPER1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESRRG;PPARG;ESR1;NR1I2;RXRA GO:0001701| in utero embryonic development HSD17B2;RXRA GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway GPER1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction NR1I2;PPARG;ESR1;GPER1;CHRNA4;ESR2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2;UGT1A1 GO:0045475| locomotor rhythm NCOA2 GO:0001890| placenta development RXRA;PPARG;HSD17B2 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;RXRA;SLCO1B1;SLCO1B3;NCOA2;SLCO1C1;SLCO1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation BECN1;PPARG;GPER1;CYP1B1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;NCOA2 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048511| rhythmic process PPARG;NCOA2 GO:0007584| response to nutrient UGT1A1;PPARG GO:1904017| NCOA2 7367:[DB07863 DB09291] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 7368:[DB07863 DB01351] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0007165| signal transduction GABRA6;PPARG;GABRA5;CHRNA7;GRIA2;CHRNA4 7369:[DB07863 DB00435] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;GUCY1A2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2 GO:0043065| positive regulation of apoptotic process PPARG;IDO1 GO:0042493| response to drug CYP1A2;PPARG 7370:[DB07863 DB06652] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0016032| viral reproduction CCR5;RXRA GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4 GO:0007165| signal transduction CCR5;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;CCR5 7371:[DB07863 DB06412] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;SRD5A1 GO:0007165| signal transduction AR;PPARG GO:0014070| response to organic cyclic compound SRD5A1;PPARG GO:0043627| response to estrogen stimulus PPARG;SRD5A1 GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0008217| regulation of blood pressure PPARG;NPPB GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0043401| steroid hormone mediated signaling pathway AR;RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR GO:0030308| negative regulation of cell growth PPARG;NPPB GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;AR GO:0006629| lipid metabolic process SRD5A1;CYP2D6;CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;AR GO:0042493| response to drug SRD5A1;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;PPARG;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;AR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;AR GO:0001701| in utero embryonic development AR;RXRA GO:0016525| negative regulation of angiogenesis PPARG;NPPB GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 7372:[DB07863 DB00604] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG;CYP2C9 GO:0042493| response to drug PPARG;HTR2A GO:0016032| viral reproduction HTR2A;RXRA GO:0007186| G-protein coupled receptor signaling pathway HTR4;HTR2A;PPARG GO:0007165| signal transduction HTR3A;HTR2A;PPARG;HTR4 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A 7373:[DB07863 DB08901] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0030855| epithelial cell differentiation FGFR2;PPARG GO:0006919| activation of caspase activity RET;LCK;PPARG GO:0014070| response to organic cyclic compound PPARG;LYN GO:0043627| response to estrogen stimulus PPARG;TEK GO:0010033| response to organic substance TEK;PPARG GO:0008285| negative regulation of cell proliferation PPARG;LYN GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;SRC GO:0032869| cellular response to insulin stimulus SRC;PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;FGFR4 GO:0007165| signal transduction LYN;PPARG;KIT;RET;SRC;TEK;BCR GO:0042593| glucose homeostasis FGFR4;PPARG GO:0031100| organ regeneration PPARG;FLT3 GO:0042493| response to drug PPARG;LYN;ABCG2;ABCB1;SRC;RET;LCK GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA2;FGFR1;PPARG;RXRA GO:0045893| positive regulation of transcription, DNA-dependent RET;SRC;PPARG;RXRA GO:0001701| in utero embryonic development FGFR1;RXRA;FGFR2 GO:0060687| regulation of branching involved in prostate gland morphogenesis FGFR2;RXRA GO:0016525| negative regulation of angiogenesis PPARG;TEK GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0016032| viral reproduction RXRA;LYN;SRC;PDGFRA;KDR;LCK GO:0048469| cell maturation PPARG;FGFR1 GO:0055010| ventricular cardiac muscle tissue morphogenesis FGFR2;RXRA GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;FGFR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;KIT GO:0007507| heart development TEK;RXRA;PPARG GO:0045087| innate immune response LYN;PPARG;ABL1;LCK;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR2;NCOA2;RXRA;PPARG;FGFR1 GO:0045165| cell fate commitment PPARG;FGFR2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0043065| positive regulation of apoptotic process ABL1;SRC;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;NCOA2;RXRA;PPARG GO:0071300| cellular response to retinoic acid PPARG;LYN;RET;FGFR2 GO:0009612| response to mechanical stimulus PPARG;SRC 7374:[DB07863 DB11581] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B1 GO:0008285| negative regulation of cell proliferation BCL2;PPARG GO:0042493| response to drug ABCB1;ABCG2;BCL2;PPARG GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 7375:[DB07863 DB01138] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound ABCC4;PPARG GO:0015721| bile acid and bile salt transport ABCC3;NCOA2;ABCB11;RXRA GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0010033| response to organic substance ABCC4;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007165| signal transduction PPARG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;NR1I2 GO:0042493| response to drug ABCC2;SLC22A12;ABCC4;PPARG;ABCC6;ABCC1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;NR1I2 GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1I2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;NR1I2;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 7376:[DB07863 DB06713] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PGR;AR;RXRA;PPARG GO:0001701| in utero embryonic development RXRA;AR GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;AR GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;AR;PGR GO:0006629| lipid metabolic process PPARG;CYP3A4;STS GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RXRA;PPARG;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;AR;PGR GO:0043401| steroid hormone mediated signaling pathway AR;PGR;PPARG;RXRA GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;AR;PGR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG;RXRA GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0007165| signal transduction PPARG;PGR;AR 7377:[DB07863 DB00637] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0007165| signal transduction HRH1;PPARG GO:0007186| G-protein coupled receptor signaling pathway HRH1;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 GO:0006919| activation of caspase activity MAPT;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0042493| response to drug ABCB1;PPARG 7378:[DB07863 DB01252] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes PPARG common pathways GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0032869| cellular response to insulin stimulus PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;RXRA;NCOA2 GO:0007165| signal transduction ABCC8;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0033993| response to lipid PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound PPARG GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process NCOA2;PPARG GO:0007584| response to nutrient PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0008217| regulation of blood pressure PPARG GO:0031000| response to caffeine PPARG GO:0045600| positive regulation of fat cell differentiation PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development RXRA;PPARG GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0030308| negative regulation of cell growth PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2 GO:0007507| heart development RXRA;PPARG GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation PPARG GO:0006629| lipid metabolic process UGT2B7;PPARG GO:0035902| response to immobilization stress PPARG GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2 GO:0071300| cellular response to retinoic acid PPARG GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0030224| monocyte differentiation PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0042493| response to drug ABCC8;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0016525| negative regulation of angiogenesis ABCC8;PPARG GO:0033189| response to vitamin A PPARG GO:1904706| PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG 7379:[DB07863 DB00814] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;PPARG;ABCC4 GO:0008217| regulation of blood pressure PPARG;PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0010033| response to organic substance ABCC4;PTGS2;PPARG GO:0007566| embryo implantation RXRA;PTGS2 GO:0042493| response to drug ABCC4;PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4;CYP2C9;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG 7380:[DB07863 DB01254] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A1;PPARG;FYN;LYN;CYP1A2;ABCG2;PPAT;SRC;ABCB1;LCK GO:0006355| regulation of transcription, DNA-dependent RXRA;MAPK14;PPARG;NCOA2;HSPA8;ABL1;STAT5B;BTK;NR4A3 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;NR4A3;SRC GO:0051289| protein homotetramerization RXRA;PPAT GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR4A3 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0016032| viral reproduction LCK;SRC;HSPA8;LYN;EPHA2;RXRA;FYN GO:0046321| positive regulation of fatty acid oxidation NR4A3;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR4A3 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;MAPK14;KIT;STAT5B GO:0048469| cell maturation BTK;PPARG GO:0032526| response to retinoic acid PPARG;PDGFRB;RXRA GO:0043401| steroid hormone mediated signaling pathway NR4A3;RXRA;PPARG GO:0006351| transcription, DNA-dependent STAT5B;NR4A3;BTK;MAPK14;PPARG;RXRA;HSPA8;NCOA2 GO:0043065| positive regulation of apoptotic process ABL1;SRC;CYP1B1;PDGFRB;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;MAPK14;NCOA2;YES1;NR4A3;STAT5B GO:0071300| cellular response to retinoic acid PPARG;ABL2;LYN;YES1 GO:0009612| response to mechanical stimulus PPARG;SRC GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;FRK;NR4A3 GO:0045087| innate immune response ABL2;LYN;FGR;PPARG;FYN;CSK;FRK;ABL1;YES1;LCK;BTK;SRC GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0006919| activation of caspase activity LCK;PPARG GO:0014070| response to organic cyclic compound CYP1A2;LYN;PPARG;CYP1A1;PDGFRB GO:0001890| placenta development PPARG;MAPK14;RXRA GO:0019395| fatty acid oxidation PPARG;MAPK14 GO:0043627| response to estrogen stimulus PDGFRB;PPARG GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG;BTK GO:0008285| negative regulation of cell proliferation LYN;PPARG;CSK;FRK;CYP1B1 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG;NCOA2;HSPA8 GO:0007186| G-protein coupled receptor signaling pathway PDGFRB;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;CYP1A1;PPARG GO:0032869| cellular response to insulin stimulus PPARG;PPAT;SRC GO:0031100| organ regeneration NR4A3;PPAT;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;STAT5B GO:0043010| camera-type eye development CYP1A1;RXRA GO:0033993| response to lipid PPARG;PDGFRB GO:0007165| signal transduction ABL2;LYN;PDGFRB;MAPK14;PPARG;STAT5B;KIT;SRC;BCR 7381:[DB07863 DB01059] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0048511| rhythmic process NCOA2;PPARG;TOP2A GO:0010033| response to organic substance PPARG;CYP1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;CYP1A1;PPARG GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0033189| response to vitamin A CYP1A1;PPARG GO:0042493| response to drug CYP1A1;PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0043065| positive regulation of apoptotic process TOP2A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TOP2A;PPARG;RXRA 7382:[DB07863 DB05303] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0010033| response to organic substance TNF;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;TNF;PPARG GO:0006919| activation of caspase activity TNF;PPARG GO:0007165| signal transduction PPARG;IL1R1 GO:0045994| positive regulation of translational initiation by iron RXRA;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0045893| positive regulation of transcription, DNA-dependent TNF;RXRA;PPARG GO:0043065| positive regulation of apoptotic process TNF;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;TNF;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;TNF;RXRA;PPARG 7383:[DB07863 DB00338] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0032922| circadian regulation of gene expression NCOA2;AHR GO:0030522| intracellular receptor mediated signaling pathway AHR;NCOA2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AHR;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;AHR GO:0042493| response to drug PPARG;CYP1A1;CYP1A2;ABCG2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;AHR;RXRA;PPARG GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP11A1;CYP1A2;CYP2D6 GO:0008203| cholesterol metabolic process RXRA;CYP11A1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;RXRA;PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;AHR;NCOA2 GO:0015721| bile acid and bile salt transport RXRA;ABCC3;NCOA2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;AHR;PPARG GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1 GO:0048511| rhythmic process PPARG;AHR;NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;CYP1A1;PPARG 7384:[DB07863 DB09146] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09146|Iron saccharate HBA1;TF common genes common pathways 7385:[DB07863 DB00533] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP3A4;PPARG;CYP2C9;PTGS1 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0042493| response to drug PPARG;PTGS2;CYP1A2;ABCC4 GO:0007566| embryo implantation PTGS2;RXRA GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance ABCC4;CYP1A2;PTGS2;PPARG GO:0008217| regulation of blood pressure PTGS1;PPARG;PTGS2 GO:0014070| response to organic cyclic compound ABCC4;PPARG;CYP1A2;PTGS2 7386:[DB07863 DB00083] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways GO:0043065| positive regulation of apoptotic process RHOB;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;RHOB 7387:[DB07863 DB06772] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0015721| bile acid and bile salt transport SLCO1B3;RXRA;SLCO1B1;NCOA2 7388:[DB07863 DB01395] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways GO:0007566| embryo implantation PTGS2;RXRA GO:0007165| signal transduction AR;NR3C2;PGR;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0007584| response to nutrient BCHE;PPARG GO:0010033| response to organic substance PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;PPARG;AR GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PGR;NR3C2;AR;PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;PGR;AR;NR3C2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;AR;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;AR GO:0006629| lipid metabolic process PTGS2;CYP3A4;PPARG GO:0042493| response to drug BCHE;PTGS2;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;PGR;NR3C2;AR GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;AR GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;PGR;AR;NR3C2 GO:0001701| in utero embryonic development RXRA;AR 7389:[DB07863 DB01126] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;SRD5A2;SRD5A1 GO:0006629| lipid metabolic process SRD5A1;CYP3A4;PPARG;SRD5A2 GO:0010033| response to organic substance PPARG;SRD5A2 GO:0043627| response to estrogen stimulus SRD5A1;PPARG GO:0014070| response to organic cyclic compound SRD5A2;PPARG;SRD5A1 GO:0032869| cellular response to insulin stimulus SRD5A1;PPARG 7390:[DB07863 DB06370] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP2D6 7391:[DB07863 DB09389] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0007165| signal transduction PPARG;PGR;AR GO:0032869| cellular response to insulin stimulus PPARG;SRD5A1 GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0043627| response to estrogen stimulus SRD5A1;PPARG GO:0014070| response to organic cyclic compound PPARG;SRD5A1 GO:0006629| lipid metabolic process CYP3A4;PPARG;SRD5A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;AR;PGR GO:0043401| steroid hormone mediated signaling pathway AR;PGR;PPARG;RXRA GO:0006351| transcription, DNA-dependent PGR;AR;NCOA2;RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter AR;PGR;PPARG;RXRA GO:0001701| in utero embryonic development AR;RXRA GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent AR;RXRA;PPARG GO:0042493| response to drug PPARG;SRD5A1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;PGR;AR 7392:[DB07863 DB08807] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0007165| signal transduction PPARG;HTR1A;ADRB2;ADRB1;HTR1B;ADRB3 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;PPARG;ADRB2;HTR1B;ADRB1;ADRB3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;ADRB2;RXRA GO:0009409| response to cold ADRB2;PPARG;ADRB1;ADRB3 GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0042493| response to drug HTR1B;PPARG 7393:[DB07863 DB11130] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0045087| innate immune response PPARG;B2M GO:0042493| response to drug PPARG;B2M GO:0007165| signal transduction PPARG;OPRD1;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PPARG;OPRK1 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG 7394:[DB07863 DB06734] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 7395:[DB07863 DB00589] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007165| signal transduction DRD1;ADRA2A;HTR2C;HTR2B;DRD5;HTR7;DRD2;HTR1B;DRD3;ADRA2B;HTR2A;ADRA2C;PPARG;DRD4;HTR1A;HTR1D GO:0007186| G-protein coupled receptor signaling pathway HTR2B;HTR2C;ADRA2A;DRD1;HTR1B;DRD2;HTR7;DRD5;HTR1A;DRD4;PPARG;ADRA2C;HTR2A;ADRA2B;DRD3;HTR1D GO:0019216| regulation of lipid metabolic process PPARG;DRD3;RXRA;NCOA2 GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0048511| rhythmic process NCOA2;DRD4;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA;DRD3 GO:0007507| heart development RXRA;PPARG;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0007623| circadian rhythm NCOA2;HTR7 GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0042493| response to drug PPARG;DRD3;HTR2A;HTR2C;HTR2B;DRD1;HTR1B;DRD2 7396:[DB07863 DB01200] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;HTR2C GO:0008285| negative regulation of cell proliferation PPARG;DRD2;ADRA1A GO:0048511| rhythmic process DRD4;PPARG;NCOA2 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;DRD3 GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;HTR2B;HTR2C;ADRA1B;DRD1;HTR1B;ADRA1A;DRD2;HTR7;DRD5;ADRA2C;HTR1A;DRD4;PPARG;DRD3;HTR2A;ADRA2B;ADRA1D;HTR1D GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0007165| signal transduction ADRA1A;DRD2;HTR1B;HTR7;DRD5;ADRA1B;HTR2B;HTR2C;ADRA2A;DRD1;ADRA1D;HTR1D;DRD4;PPARG;HTR1A;ADRA2C;ADRA2B;HTR2A;DRD3 GO:0042493| response to drug ADRA1A;DRD2;ABCB1;HTR1B;DRD1;HTR2B;HTR2C;DRD3;HTR2A;PPARG GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0007623| circadian rhythm NCOA2;HTR7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RXRA;DRD3;PPARG;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;DRD3;NCOA2 GO:0007507| heart development PPARG;RXRA;HTR2B 7397:[DB07863 DB01240] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0048662| negative regulation of smooth muscle cell proliferation PTGIR;PPARG GO:0007165| signal transduction P2RY12;PPARG;PTGIR GO:0007186| G-protein coupled receptor signaling pathway PTGIR;PPARG;P2RY12 GO:0007566| embryo implantation PTGIS;RXRA GO:0006629| lipid metabolic process PTGIS;PPARG 7398:[DB07863 DB05039] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;PPARG;ABCB1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ADRB2;RXRA;PPARG GO:0009409| response to cold ADRB2;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2 GO:0007165| signal transduction ADRB2;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 7399:[DB07863 DB04825] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;CALM1 GO:0006629| lipid metabolic process PPARG;CYP3A4 7400:[DB07863 DB09029] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09029|Secukinumab IL17A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;IL17A 7401:[DB07863 DB00836] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;POMC;OPRK1;CALM1 GO:0042593| glucose homeostasis PPARG;POMC GO:0007165| signal transduction OPRD1;NR1I3;OPRM1;PPARG;OPRK1;POMC GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0008217| regulation of blood pressure PPARG;POMC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I3;NCOA2 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1I3;PPARG;RXRA GO:0006351| transcription, DNA-dependent NR1I3;NCOA2;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NR1I3;NCOA2;POMC GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NR1I3;NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NR1I3;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1I3 7402:[DB07863 DB12332] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0032869| cellular response to insulin stimulus PARP1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance ABCC4;CYP1A2;UGT1A1;PPARG GO:0015721| bile acid and bile salt transport RXRA;SLCO1B1;SLCO1B3;NCOA2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;PPARG;ABCC4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PARP1;RXRA;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2C9;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;PARP1 GO:0006351| transcription, DNA-dependent NCOA2;PARP1;PPARG;RXRA GO:0042493| response to drug ABCG2;ABCC4;ABCB1;PPARG;CYP1A2;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PARP1;PPARG;RXRA 7403:[DB07863 DB14635] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes PPARG common pathways GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA GO:0042493| response to drug PPARG;CYP1A2;ABCB1 GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;VDR GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0030224| monocyte differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:1904706| PPARG;GSTP1 GO:0042752| regulation of circadian rhythm PPARG GO:0006367| transcription initiation from RNA polymerase II promoter VDR;RXRA;PPARG GO:0050872| white fat cell differentiation PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway VDR;RXRA;PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;VDR GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG GO:0009409| response to cold PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;VDR GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4;CYP1A2 GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0007507| heart development RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;RXRA;PPARG;NCOA2 GO:0045087| innate immune response PPARG GO:0045165| cell fate commitment PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0030855| epithelial cell differentiation PPARG;CBR1;GSTA1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;RXRA GO:0019395| fatty acid oxidation PPARG GO:0045600| positive regulation of fat cell differentiation PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation VDR;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG GO:0008217| regulation of blood pressure PPARG GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG;NCOA2 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG GO:0048511| rhythmic process PPARG;NCOA2 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;GSTP1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration PPARG;GSTP1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction VDR;PPARG 7404:[DB07863 DB00877] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0007165| signal transduction MTOR;FGF2;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;FGF2 GO:0031000| response to caffeine PPARG;FKBP1A GO:0007584| response to nutrient MTOR;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation MTOR;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;FGF2;RXRA;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0055010| ventricular cardiac muscle tissue morphogenesis RXRA;FKBP1A GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;FGF2 GO:0042493| response to drug PPARG;ABCB1 7405:[DB07863 DB11712] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG 7406:[DB07863 DB06212] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCB1 GO:0032870| cellular response to hormone stimulus AVPR2;AVPR1A;NCOA2 GO:0007165| signal transduction PPARG;AVPR1A;AVPR2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;AVPR1A;AVPR2 GO:0010033| response to organic substance AVPR1A;PPARG 7407:[DB07863 DB05668] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05668|Palifosfamide DNMT1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;DNMT1 GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;DNMT1 GO:0006355| regulation of transcription, DNA-dependent DNMT1;RXRA;PPARG;NCOA2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;DNMT1 7408:[DB07863 DB01102] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0009409| response to cold ADRB3;ADRB1;ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0007165| signal transduction PPARG;ADRB2;ADRB1;ADRB3 GO:0007186| G-protein coupled receptor signaling pathway ADRB3;ADRB1;PPARG;ADRB2 7409:[DB07863 DB00655] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1A2;NCOA2;SLCO1B1;RXRA GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;AR GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction PPARG;ESR1;ESR2;AR GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;CYP4A11;NCOA2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1;ESR2 GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0033189| response to vitamin A CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;ESR1;PPARG;AR;ESR2 GO:0001701| in utero embryonic development RXRA;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR2;RXRA;PPARG;ESR1 GO:0042493| response to drug ABCG2;ABCB1;PPARG;CYP1A1;CYP2E1;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;ESR1;PPARG;RXRA;AR;ESR2 GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR2;NCOA2;RXRA;ESR1;PPARG GO:0006629| lipid metabolic process CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;ESR1;PPARG;NCOA2;ESR2;AR GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG;ESR1;RXRA GO:0043401| steroid hormone mediated signaling pathway AR;ESR2;PPARG;ESR1;RXRA GO:0006351| transcription, DNA-dependent NCOA2;PPARG;ESR1;RXRA;ESR2;AR 7410:[DB07863 DB00696] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug HTR2A;PPARG;SLC6A2;DRD1;HTR2B;HTR2C;HTR1B;ABCB1;ADRA1A;DRD2 GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007507| heart development HTR2B;PPARG;RXRA GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;HTR1D;HTR1A;PPARG;HTR2A;ADRA2B;HTR1B;ADRA1A;DRD2;DRD5;ADRA2A;HTR2B;HTR2C;ADRA1B;HTR1F;DRD1 GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0007165| signal transduction DRD1;HTR1F;ADRA2A;ADRA1B;HTR2C;HTR2B;DRD5;DRD2;ADRA1A;HTR1B;ADRA2B;HTR2A;PPARG;HTR1A;HTR1D;ADRA1D 7411:[DB07863 DB05087] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0007165| signal transduction GABRA6;PPARG;GABRA5 7412:[DB07863 DB04840] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;PPARG;CYP1A1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA 7413:[DB07863 DB01219] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways GO:0031000| response to caffeine RYR1;PPARG GO:0051289| protein homotetramerization RXRA;RYR1 GO:0006629| lipid metabolic process PPARG;CYP3A4 7414:[DB07863 DB00845] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCB1 GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 7415:[DB07863 DB09065] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09065|Cobicistat CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG GO:0042493| response to drug ABCB1;ABCG2;PPARG GO:0015721| bile acid and bile salt transport SLCO1B3;RXRA;SLCO1B1;NCOA2 7416:[DB07863 DB09166] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0007165| signal transduction PTAFR;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;PTAFR GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter PTAFR;RXRA;PPARG 7417:[DB07863 DB00782] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00782|Propantheline CHRM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1 GO:0007165| signal transduction CHRM1;PPARG 7418:[DB07863 DB14508] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007623| circadian rhythm NCOA2;GSK3B GO:0048511| rhythmic process NCOA2;PPARG;GSK3B GO:0007165| signal transduction PPARG;IMPA2;IMPA1 7419:[DB07863 DB00502] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00502|Haloperidol DRD2;DRD1;GRIN2B;HTR2A;DRD3;MCHR1;SLC18A2;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP3A4;CBR1;UGT1A9;CYP1A1;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0007165| signal transduction DRD1;DRD2;HTR2A;DRD3;PPARG;MCHR1 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;HTR2A;DRD3;MCHR1;DRD1;DRD2 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;DRD3;UGT1A9;NCOA2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0030855| epithelial cell differentiation PPARG;CBR1 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;DRD3;RXRA;NCOA2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2;DRD2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0042493| response to drug DRD1;DRD2;ABCB1;HTR2A;DRD3;CYP1A1;PPARG;CYP1A2 7420:[DB07863 DB00503] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00503|Ritonavir pol;NR1I2;CYP2D6;CYP2C9;CYP2C19;CYP2B6;CYP2C8;CYP1A2;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;UGT1A1;ALB;ABCB1;ABCC1;SLCO1A2;ABCC2;ABCG2;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG GO:0042493| response to drug CYP1A2;UGT1A1;ABCC1;PPARG;CYP2E1;ABCB1;ABCG2;ABCC2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2;RXRA GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;NR1I2;PPARG;NCOA2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;CYP1A2;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR1I2 GO:0006351| transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0015721| bile acid and bile salt transport NCOA2;SLCO1A2;ABCB11;RXRA;SLCO1B1;SLCO2B1;ALB GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance PPARG;CYP1A2;UGT1A1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1;CYP1A2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1;NCOA2 GO:0007165| signal transduction PPARG;NR1I2 7421:[DB07863 DB08838] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0007165| signal transduction CHRNA1;PPARG;ADRA2C;ASIC3 GO:0007186| G-protein coupled receptor signaling pathway ADRA2C;PPARG GO:0008217| regulation of blood pressure NISCH;PPARG;CACNA1B GO:0009612| response to mechanical stimulus ASIC3;PPARG GO:0043065| positive regulation of apoptotic process PPARG;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 7422:[DB07863 DB00131] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0014070| response to organic cyclic compound ACSL1;PPARG GO:0048511| rhythmic process PRKAA1;ADCY1;CREB1;PPARG;NCOA2 GO:0007584| response to nutrient ACSL1;PPARG GO:0031000| response to caffeine PPARG;PRKAA1 GO:0010033| response to organic substance ACSL1;AMPD1;CREB1;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG;PRKAA1 GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0019395| fatty acid oxidation PRKAA1;PPARG GO:0032869| cellular response to insulin stimulus APRT;PPARG GO:0007186| G-protein coupled receptor signaling pathway PDE4B;ADCY1;PPARG;PDE4D GO:0019216| regulation of lipid metabolic process ACSL1;NCOA2;PPARG;RXRA GO:0007165| signal transduction PDE4D;CREB1;HINT1;PPARG;ADCY1;PRKAA1;PRKAB2;PDE4B;PRKAB1 GO:0042593| glucose homeostasis PYGL;PPARG;PRKAA1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;CREB1;HINT1;PRKAA1 GO:0042493| response to drug ACSL1;ADCY1;CREB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;RXRA GO:0042752| regulation of circadian rhythm PPARG;CREB1;ADCY1;PRKAA1 GO:0051289| protein homotetramerization FBP1;RXRA GO:0016032| viral reproduction RXRA;CREB1 GO:0006351| transcription, DNA-dependent NCOA2;PPARG;CREB1;HINT1;RXRA;PRKAA1 GO:0007623| circadian rhythm ADCY1;CREB1;NCOA2 GO:0008203| cholesterol metabolic process PRKAA1;RXRA GO:0030308| negative regulation of cell growth PPARG;FBP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;FBP1 GO:0006629| lipid metabolic process PRKAB2;PRKAB1;ACSL1;PRKAA1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;CREB1;RXRA GO:0043065| positive regulation of apoptotic process CREB1;PPARG 7423:[DB07863 DB00594] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;SLC9A1 GO:0007165| signal transduction PLAU;PPARG;ASIC1 GO:0014070| response to organic cyclic compound SLC9A1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;SLC9A1 GO:0043065| positive regulation of apoptotic process SLC9A1;PPARG GO:0009612| response to mechanical stimulus PPARG;ASIC2 GO:0042493| response to drug PPARG;AOC1 7424:[DB07863 DB06288] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RXRA;PPARG;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG GO:0007623| circadian rhythm HTR7;NCOA2 GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression DRD2;NCOA2;DRD3 GO:0042493| response to drug DRD2;PPARG;HTR2A;DRD3 GO:0007165| signal transduction DRD2;HTR7;PPARG;DRD3;HTR2A GO:0019216| regulation of lipid metabolic process NCOA2;DRD3;RXRA;PPARG GO:0007186| G-protein coupled receptor signaling pathway DRD2;HTR7;PPARG;DRD3;HTR2A GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008285| negative regulation of cell proliferation PPARG;DRD2 7425:[DB07863 DB09282] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0007165| signal transduction GUCY1A2;PPARG;PDE5A 7426:[DB07863 DB00630] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0016032| viral reproduction RXRA;FDPS GO:0008203| cholesterol metabolic process FDPS;RXRA GO:0006629| lipid metabolic process FDPS;PPARG 7427:[DB07863 DB00237] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GABRB3;CHRNA7;CHRNA4;GRIA2;PPARG;GABRA6;GABRD;GABRP;GABRE;GABRB1;GABRA5;GABRQ GO:0042493| response to drug PPARG;GABRG3 7428:[DB07863 DB09053] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0045087| innate immune response PPARG;BTK GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;BTK GO:0048469| cell maturation PPARG;BTK GO:0006355| regulation of transcription, DNA-dependent BTK;NCOA2;RXRA;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0010033| response to organic substance BTK;PPARG 7429:[DB07863 DB00276] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0048511| rhythmic process TOP2A;PPARG;NCOA2 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0042493| response to drug ABCB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;TOP2A 7430:[DB07863 DB00458] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00458|Imipramine SLC6A2;HTR2A;SLC6A4;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCND2;KCND3;HTR2C;ADRA1B;HTR7;DRD1;DRD5;DRD2;KCNH2;SLC6A3;HTR1A;HTR6;KCNH1;ORM2;CYP2C19;CYP2D6;CYP1A2;CYP3A4;CYP3A7;CYP2B6;CYP2C18;CYP2E1;ORM1;ALB;ABCB1;SLC22A2;SLC22A3;SLC22A4 common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0042493| response to drug CYP2E1;PPARG;HTR2A;CYP1A2;SLC6A2;SLC6A4;HTR2C;SLC6A3;DRD1;ABCB1;DRD2;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RXRA;PPARG;NCOA2 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2D6 GO:0007623| circadian rhythm NCOA2;SLC6A4;HTR7 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0045600| positive regulation of fat cell differentiation HTR2C;HTR2A;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance PPARG;CYP1A2;SLC6A4 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0014070| response to organic cyclic compound SLC6A3;CYP1A2;PPARG GO:0045475| locomotor rhythm NCOA2;KCND2 GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0007165| signal transduction DRD1;HTR6;HTR2C;ADRA1B;HTR7;DRD5;CHRM4;ADRA1A;DRD2;HTR2A;CHRM2;HTR1A;PPARG;CHRM1;HRH1;CHRM3;ADRA1D;CHRM5 GO:0007186| G-protein coupled receptor signaling pathway DRD1;ADRA1B;HTR2C;HTR6;CHRM4;DRD5;HTR7;DRD2;ADRA1A;HTR2A;CHRM2;PPARG;HTR1A;CHRM1;HRH1;CHRM3;CHRM5;ADRA1D 7431:[DB07863 DB00346] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRA1B;ADRA1D;PPARG GO:0007165| signal transduction ADRA1A;ADRA1B;ADRA1D;PPARG GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0042493| response to drug PPARG;ADRA1A GO:0006629| lipid metabolic process PPARG;CYP3A4 7432:[DB07863 DB00675] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0042953| lipoprotein transport PRKCB;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP2D6;EBP;SULT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;ESR1;ESR2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;NR1I2;ESR1;PPARG;ESRRG;ESR2;AR GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG GO:0006351| transcription, DNA-dependent ESRRG;PRKCB;AR;ESR2;NCOA2;NR1I2;RXRA;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;AR;ESRRG;RXRA;NR1I2;ESR1;PPARG GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0008203| cholesterol metabolic process EBP;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;AR;RXRA;ESR1;PPARG GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0001701| in utero embryonic development AR;RXRA GO:0042752| regulation of circadian rhythm PRKCG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG;ESR1;ESRRG;ESR2;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1;PPARG GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2;AR GO:0048384| retinoic acid receptor signaling pathway ESRRG;RXRA GO:0045893| positive regulation of transcription, DNA-dependent RXRA;NR1I2;ESR1;PPARG;ESR2;AR;ESRRG GO:0006355| regulation of transcription, DNA-dependent NCOA2;ESR1;PPARG;RXRA;NR1I2;PRKCB;PRKCQ;ESRRG;AR;ESR2 GO:0042493| response to drug ABCB1;ABCG2;ABCC2;CYP1A1;PPARG;CYP2E1 GO:0007165| signal transduction PRKCD;NR1I2;ESR1;PRKCE;PPARG;PRKCZ;PRKCB;AR;ESR2;EBP GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0032869| cellular response to insulin stimulus PRKCZ;PRKCI;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;CYP1A1;PPARG;PRKCE GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0010033| response to organic substance CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;AR;CYP1B1 GO:0048511| rhythmic process PPARG;NCOA2;PRKCG GO:0043627| response to estrogen stimulus ABCC2;PPARG;ESR1 GO:0071380| cellular response to prostaglandin E stimulus PRKCE;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG 7433:[DB07863 DB14065] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process PPARG;CYP3A4 7434:[DB07863 DB01496] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction CHRNA4;GRIA2;CHRNA7;GABRA5;PPARG;GABRA6 7435:[DB07863 DB11637] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 7436:[DB07863 DB06148] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0007623| circadian rhythm NCOA2;HTR7;SLC6A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;DRD3;RXRA GO:0007507| heart development HTR2B;PPARG;RXRA GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;DRD3;NCOA2 GO:0042493| response to drug PPARG;DRD3;HTR2A;CYP1A2;SLC6A2;SLC6A4;HTR2C;HTR2B;SLC6A3;DRD1;DRD2;ADRA1A GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0019216| regulation of lipid metabolic process DRD3;RXRA;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;HRH1;HTR1A;PPARG;ADRA2C;HTR2A;ADRA2B;HRH4;DRD3;DRD2;ADRA1A;DRD5;HTR7;HTR2C;HTR2B;HTR6;ADRA1B;ADRA2A;HTR1F;DRD1;OPRK1 GO:0007165| signal transduction HTR1A;PPARG;ADRA2C;HTR2A;ADRA2B;HRH4;DRD3;ADRA1D;HRH1;HTR2C;HTR2B;HTR6;ADRA1B;ADRA2A;HTR1F;DRD1;OPRK1;DRD2;ADRA1A;DRD5;HTR7 GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2;SLC6A3 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0010033| response to organic substance CYP1A2;PPARG;SLC6A4 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C 7437:[DB07863 DB00315] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0042493| response to drug HTR1B;CYP1A2;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR1F;HTR1B;PPARG;HTR1A;HTR1D GO:0007165| signal transduction HTR1B;HTR1F;HTR1D;HTR1A;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG 7438:[DB07863 DB07720] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0007165| signal transduction CHRNA7;CHRNA4;CHRNA3;CHRNA2;CHRFAM7A;PPARG;CHRNB4;CHRNB2 7439:[DB07863 DB03566] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0009409| response to cold PPARG;ADRB2;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;ADRB2 GO:0007165| signal transduction PPARG;ADRB2;ADRB1;TXNRD1 GO:0019216| regulation of lipid metabolic process TXNRD1;NCOA2;PPARG;RXRA GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2;ADRB1 7440:[DB07863 DB01074] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;CPT2;CPT1A GO:0014070| response to organic cyclic compound CPT1A;PPARG GO:0030855| epithelial cell differentiation PPARG;CPT1A GO:0007623| circadian rhythm NCOA2;CPT1A GO:0006629| lipid metabolic process CYP2D6;CPT1A;CYP3A4;PPARG;CPT2 GO:0042493| response to drug PPARG;CPT1A 7441:[DB07863 DB05091] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05091|M0002 AVPR2 common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;AVPR2 GO:0007165| signal transduction PPARG;AVPR2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;AVPR2 7442:[DB07863 DB06595] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PPARG;PDGFRB GO:0010033| response to organic substance PPARG;CYP1A2 GO:0043627| response to estrogen stimulus PPARG;PDGFRB GO:0007186| G-protein coupled receptor signaling pathway PPARG;PDGFRB GO:0007165| signal transduction KIT;PPARG;PDGFRB GO:0033993| response to lipid PDGFRB;PPARG GO:0031100| organ regeneration PPARG;FLT3 GO:0042493| response to drug CYP1A2;PPARG;CYP2E1 GO:0016032| viral reproduction RXRA;PDGFRA;KDR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;KIT GO:0032526| response to retinoic acid RXRA;PPARG;PDGFRB GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;RXRA;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0043065| positive regulation of apoptotic process PDGFRB;PPARG 7443:[DB07863 DB00790] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;SFRP4 GO:0008285| negative regulation of cell proliferation BCHE;PPARG;SFRP4 GO:0008217| regulation of blood pressure ACE;PPARG GO:0007584| response to nutrient PPARG;BCHE GO:0043065| positive regulation of apoptotic process PPARG;SFRP4 GO:0042493| response to drug BCHE;PPARG 7444:[DB07863 DB01296] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0007566| embryo implantation MMP9;RXRA GO:0045994| positive regulation of translational initiation by iron RXRA;TNF GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IFNG GO:0043388| positive regulation of DNA binding MMP9;PPARG GO:0007165| signal transduction NFKB2;PPARG GO:0006919| activation of caspase activity PPARG;TNF GO:0048511| rhythmic process PPARG;NFKB2;NCOA2 GO:0010033| response to organic substance PPARG;TNF GO:0045892| negative regulation of transcription, DNA-dependent IFNG;TNF;PPARG;NCOA2 GO:0006351| transcription, DNA-dependent RXRA;NFKB2;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;MMP9;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;NFKB2;RXRA;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;NFKB2;RXRA;TNF;PPARG;NCOA2 GO:0045087| innate immune response NFKB2;PPARG GO:0042493| response to drug PPARG;CYP2E1 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NFKB2;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;TNF;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF 7445:[DB07863 DB00849] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;RXRA GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;NR1I2;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1I2;RXRA;NCOA2 GO:0006351| transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR1I2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0007165| signal transduction CHRNA7;GRIA2;CHRNA4;GABRA6;PPARG;NR1I2;GABRA5 7446:[DB07863 DB01412] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADORA2A;ADORA1;PPARG;PDE4B GO:0007165| signal transduction ADORA1;PPARG;ADORA2A;PDE4B GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADORA1;ADORA2A GO:0010033| response to organic substance PPARG;CYP1A2 GO:0031000| response to caffeine PPARG;ADORA2A GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042493| response to drug CYP2E1;PPARG;ADORA2A;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ADORA2A;RXRA 7447:[DB07863 DB04827] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;PPARG GO:0009612| response to mechanical stimulus PPARG;MPO 7448:[DB07863 DB00549] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0007165| signal transduction CYSLTR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway CYSLTR1;PPARG GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PTGS1;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0042493| response to drug PPARG;CYP2E1;CYP1A2;ABCG2 7449:[DB07863 DB00531] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;RXRA GO:0006351| transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;NR1I2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;NR1I2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0007165| signal transduction NR1I2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 7450:[DB07863 DB06700] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0042493| response to drug SLC6A4;PPARG;SLC6A2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance SLC6A4;PPARG 7451:[DB07863 DB00852] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent RXRA;FOS;TNF;ATF4;PPARG;JUN;NFATC1;ATF5 GO:0042493| response to drug FOS;PPARG;JUN;SLC6A2;SLC6A3;SLC6A4;ADRA1A GO:0006355| regulation of transcription, DNA-dependent NCOA2;JDP2;JUN;ATF6;PPARG;RXRA;ATF3;ATF4;FOS;ATF7;ATF2;NFATC1;ATF1;ATF5 GO:0030224| monocyte differentiation PPARG;JUN GO:0016032| viral reproduction ATF7;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG;ATF2 GO:0032922| circadian regulation of gene expression ATF4;NCOA2 GO:0016525| negative regulation of angiogenesis ATF2;PPARG GO:0007623| circadian rhythm ATF4;NCOA2;JUN;SLC6A4;ATF5 GO:0006357| regulation of transcription from RNA polymerase II promoter ATF2;ATF5;ATF1;JDP2;PPARG;ATF6;FOS;ATF4;ATF3;RXRA GO:0006351| transcription, DNA-dependent ATF7;ATF2;ATF5;ATF1;NFATC1;JDP2;JUN;NCOA2;PPARG;ATF6;ATF4;RXRA;ATF3 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0009409| response to cold ADRB2;FOS;PPARG;ADRB1 GO:0009612| response to mechanical stimulus FOS;PPARG;JUN GO:0043065| positive regulation of apoptotic process JUN;ATF4;TNF;PPARG;ATF6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFATC1;ATF1;ATF5;IL2;ATF2;ATF6;PPARG;ATF3;RXRA;ADRB2;TNF;FOS;ATF4;NCOA2;JUN GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0035902| response to immobilization stress FOS;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ATF7;ATF2;PPARG;TNF;ATF3;RXRA;JDP2;NCOA2 GO:0006919| activation of caspase activity PPARG;TNF GO:0014070| response to organic cyclic compound SLC6A3;ATF1;FOS;PPARG;JUN GO:0008285| negative regulation of cell proliferation PPARG;JUN;ATF5;ADRA1A GO:0010033| response to organic substance JUN;TNF;PPARG;SLC6A4 GO:0045892| negative regulation of transcription, DNA-dependent ATF3;TNF;PPARG;NCOA2;JUN;ATF5 GO:0048511| rhythmic process NCOA2;ATF4;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRB1;IL2;ADRA2A;ADRB2;PPARG GO:0045994| positive regulation of translational initiation by iron RXRA;TNF GO:0032870| cellular response to hormone stimulus NCOA2;JUN;FOS;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0007165| signal transduction ADRA1A;ADRB1;ADRA2A;PPARG;ATF6;ADRB2 7452:[DB07863 DB01588] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;GABRG3 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007165| signal transduction GABRD;GABRA6;PPARG;GABRP;GABRR2;GABRE;GABRQ;GABRA5;GABRB1;GABRB3 7453:[DB07863 DB00396] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG;ESR1;NR3C1;NR3C2;AR;PGR GO:0001701| in utero embryonic development RXRA;AR GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2;NR1I2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0016032| viral reproduction SLC10A1;RXRA GO:0042493| response to drug PPARG;CYP1A1;ABCC1;ABCG2;ABCB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR3C1;ESR1;PPARG;RXRA;NR1I2;PGR;AR;NR3C2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;RXRA;NR1I2;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2;NR3C1;AR GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;ESR1;NR1I2;RXRA;PGR;AR GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1I2;ESR1;PPARG;NR3C1;AR;NR3C2;PGR GO:0006351| transcription, DNA-dependent RXRA;NR1I2;ESR1;PPARG;NCOA2;NR3C1;AR;NR3C2;PGR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG;RXRA GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0008285| negative regulation of cell proliferation CYP1B1;AR;PPARG GO:0010033| response to organic substance PPARG;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0015721| bile acid and bile salt transport SLC10A1;SLCO1B1;ABCB11;RXRA;NCOA2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0007165| signal transduction PGR;AR;NR3C2;OPRK1;NR3C1;ESR1;PPARG;NR1I2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 7454:[DB07863 DB00289] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance SLC6A4;PPARG GO:0042493| response to drug SLC6A2;PPARG;SLC6A4;GRIN2A;SLC6A3 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;PPARG;RXRA GO:0043065| positive regulation of apoptotic process GRIN2A;PPARG;GRIN1 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 7455:[DB07863 DB00946] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00946|Phenprocoumon VKORC1;CYP2C8;CYP2C9;CYP3A4;ALB;ORM1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 7456:[DB07863 DB06751] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0007507| heart development CACNA1C;RXRA;PPARG GO:0007165| signal transduction PDE4A;PPARG GO:0043010| camera-type eye development RXRA;CACNA1C GO:0007186| G-protein coupled receptor signaling pathway PDE4A;PPARG 7457:[DB07863 DB05521] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;SLCO1B1;RXRA;ALB;SLCO2B1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug ABCB1;PPARG 7458:[DB07863 DB01288] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0009409| response to cold PPARG;ADRB2;ADRB3;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RXRA;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG;ADRB3;ADRB1 GO:0007165| signal transduction ADRB1;ADRB3;PPARG;ADRB2 7459:[DB07863 DB08827] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process MTTP;PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCB1 7460:[DB07863 DB06155] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways GO:0007584| response to nutrient CNR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway CNR1;PPARG;GPR55 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CNR1;RXRA GO:0007165| signal transduction PPARG;GPR55;CNR1 GO:0042593| glucose homeostasis PPARG;CNR1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043065| positive regulation of apoptotic process CNR1;PPARG 7461:[DB07863 DB06274] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0007165| signal transduction OPRK1;PPARG;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PPARG;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0043627| response to estrogen stimulus PPARG;OPRK1 7462:[DB07863 DB11431] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7463:[DB07863 DB06292] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;UGT1A9;NCOA2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0006629| lipid metabolic process UGT2B7;CYP2D6;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0042493| response to drug CYP1A2;CYP1A1;PPARG;ABCB1 7464:[DB07863 DB00715] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug SLC6A4;ABCB1;PPARG;HTR2A;CYP1A2;SLC6A2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;CYP1A2;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance CYP1A2;PPARG;SLC6A4 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007165| signal transduction CHRM3;CHRM5;HTR2A;CHRM2;PPARG;CHRM1;CHRM4 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;CHRM5;CHRM2;HTR2A;CHRM1;PPARG;CHRM4 7465:[DB07863 DB00567] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 7466:[DB07863 DB01483] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007165| signal transduction CHRNA7;GRIA2;CHRNA4;GABRA6;PPARG;GABRA5 7467:[DB07863 DB00834] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes common pathways GO:0007165| signal transduction NR1I2;PPARG;NR3C1;PGR GO:0015721| bile acid and bile salt transport NCOA2;ABCB11;RXRA GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA;NR1I2;PGR GO:0006351| transcription, DNA-dependent PGR;NCOA2;NR3C1;PPARG;RXRA;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;RXRA;NR1I2;PPARG;PGR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NR3C1;NCOA2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG;CYP2C9 GO:0042493| response to drug ABCB1;ABCC1;PPARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;NR3C1;NCOA2;PGR GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;NR3C1;NR1I2;RXRA;PPARG GO:0016525| negative regulation of angiogenesis PPARG;KLK3 7468:[DB07863 DB00978] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;TOP2A GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP1A2 GO:0042493| response to drug CYP1A2;PPARG;ABCC2 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0048511| rhythmic process TOP2A;PPARG;NCOA2 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0010033| response to organic substance PPARG;CYP1A2 7469:[DB07863 DB06603] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0010033| response to organic substance HDAC6;PPARG GO:0008285| negative regulation of cell proliferation PPARG;HDAC4;HDAC1 GO:0031000| response to caffeine HDAC2;HDAC1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent HDAC1;HDAC4;PPARG;HDAC6;HDAC7;NCOA2;HDAC9;HDAC3;HDAC2;HDAC5;HDAC10 GO:0048511| rhythmic process HDAC2;NCOA2;HDAC1;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;PPARG;HDAC1 GO:0019216| regulation of lipid metabolic process HDAC3;RXRA;PPARG;NCOA2 GO:0032869| cellular response to insulin stimulus HDAC5;HDAC9;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC5;PPARG;HDAC4 GO:0016032| viral reproduction RXRA;HDAC1 GO:0032922| circadian regulation of gene expression HDAC1;NCOA2;HDAC2 GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;RXRA;HDAC1;HDAC4;PPARG GO:0042493| response to drug HDAC4;PPARG;HDAC1;HDAC2;HDAC5;ABCB1 GO:0006355| regulation of transcription, DNA-dependent HDAC3;HDAC9;HDAC2;HDAC8;HDAC5;HDAC10;HDAC1;RXRA;HDAC4;PPARG;HDAC6;HDAC7;NCOA2;HDAC11 GO:0071300| cellular response to retinoic acid PPARG;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC5;HDAC2;HDAC3;HDAC4;PPARG;RXRA;HDAC1;NCOA2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0007507| heart development HDAC9;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC7;NCOA2;HDAC1;RXRA;PPARG;HDAC4;HDAC10;HDAC3;HDAC9;HDAC2;HDAC8;HDAC5 GO:0007623| circadian rhythm HDAC3;NCOA2 GO:0045598| regulation of fat cell differentiation HDAC6;PPARG GO:0006351| transcription, DNA-dependent HDAC10;HDAC9;HDAC3;HDAC8;HDAC2;HDAC5;HDAC7;HDAC11;NCOA2;HDAC1;RXRA;HDAC4;PPARG;HDAC6 7470:[DB07863 DB09030] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;F2R;PPARG GO:0007186| G-protein coupled receptor signaling pathway F2R;PPARG GO:0007165| signal transduction F2R;PPARG GO:0006919| activation of caspase activity PPARG;F2R GO:0008285| negative regulation of cell proliferation PPARG;F2R 7471:[DB07863 DB00537] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;TOP2A;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;TOP2A GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0042493| response to drug ABCB1;CYP1A2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0048511| rhythmic process TOP2A;PPARG;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 7472:[DB07863 DB00305] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00305|Mitomycin POR common genes common pathways GO:0007584| response to nutrient PPARG;POR GO:0019395| fatty acid oxidation POR;PPARG GO:0042493| response to drug PPARG;POR 7473:[DB07863 DB00501] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00501|Cimetidine HRH2;CYP1A2;CYP2C19;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP11B1;CYP2C8;CYP2C9;CYP2E1;FMO3;FMO1;ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A6;SLC22A8;SLC47A1;SLC22A4;SLC22A11;SLC22A7;ABCB11;SLC47A2 common genes common pathways GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0032870| cellular response to hormone stimulus NCOA2;CYP11B1 GO:0007165| signal transduction HRH2;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;HRH2 GO:0015721| bile acid and bile salt transport ABCB11;RXRA;NCOA2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP11B1;CYP1A2;CYP3A4;CYP2C9;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042493| response to drug CYP2E1;PPARG;CYP1A2;ABCB1 7474:[DB07863 DB00619] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent RET;PPARG;RXRA GO:0042493| response to drug NTRK1;PPARG;ABCA3;CYP1A2;ABCG2;RET;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;NCOA2;RXRA;PPARG GO:0030224| monocyte differentiation PPARG;CSF1R GO:0016032| viral reproduction PDGFRA;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;KIT GO:0007623| circadian rhythm NCOA2;NTRK1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;KIT GO:0032526| response to retinoic acid PPARG;PDGFRB;RXRA GO:0071300| cellular response to retinoic acid RET;PPARG GO:0043065| positive regulation of apoptotic process PDGFRB;PPARG;ABL1 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4;CYP1A2;CYP2D6;PTGS1 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045087| innate immune response PPARG;ABL1;CSF1R GO:0006919| activation of caspase activity PPARG;RET GO:0014070| response to organic cyclic compound CYP1A2;PPARG;PDGFRB GO:0015721| bile acid and bile salt transport NCOA2;ABCB11;RXRA;ALB GO:0010033| response to organic substance PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation DDR1;NTRK1;PPARG;CSF1R GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0043627| response to estrogen stimulus PDGFRB;PPARG GO:0007566| embryo implantation RXRA;DDR1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;PDGFRB GO:0033993| response to lipid PDGFRB;PPARG GO:0007165| signal transduction CSF1R;KIT;RET;PDGFRB;PPARG 7475:[DB07863 DB01263] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug ABCB1;PPARG 7476:[DB07863 DB08882] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCB1 7477:[DB07863 DB00182] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0042493| response to drug ADRA1A;DRD2;SLC6A4;SLC6A3;MAOB;SLC6A2;PPARG GO:0032922| circadian regulation of gene expression DRD2;CARTPT;NCOA2 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0009409| response to cold PPARG;ADRB2;ADRB1;ADRB3 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ADRB2;RXRA;NCOA2;DRD2 GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0014070| response to organic cyclic compound SLC6A3;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA2C;PPARG;ADRA2B;ADRB2;TAAR1;ADRA1D;ADRA2A;ADRA1B;ADRB3;ADRB1;DRD2;ADRA1A;CARTPT GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis PPARG;ADRA2A;ADRA1B GO:0007165| signal transduction TAAR1;ADRA1D;ADRB2;ADRA2B;ADRA2C;PPARG;CARTPT;ADRB1;ADRA1A;DRD2;ADRB3;ADRA2A;ADRA1B 7478:[DB07863 DB00921] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0010033| response to organic substance UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRM1;OPRD1;OPRK1;OPRL1 GO:0019216| regulation of lipid metabolic process PPARG;RXRA;UGT1A9;NCOA2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0007165| signal transduction PPARG;OPRD1;OPRM1;OPRK1;OPRL1 GO:0042493| response to drug PPARG;UGT1A1;ABCG2;ABCB1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP2D6 7479:[DB07863 DB01590] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0007165| signal transduction MTOR;PPARG GO:0007584| response to nutrient MTOR;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation MTOR;PPARG GO:0015721| bile acid and bile salt transport NCOA2;SLCO1A2;RXRA;SLCO1B1;SLCO1B3 GO:0006629| lipid metabolic process CYP3A4;PPARG 7480:[DB07863 DB00661] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0008217| regulation of blood pressure PPARG;CACNA1B GO:0010033| response to organic substance CYP1A2;PPARG;ABCC4;SLC6A4 GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;ABCB11;SLCO1A2;ABCC3;NCOA2 GO:0014070| response to organic cyclic compound ABCC4;PPARG;CYP1A2 GO:0007165| signal transduction PPARG;ADRA1D;ADRA1B;ADRA1A;CACNA1I GO:0043010| camera-type eye development CACNA1C;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;ADRA1A;PPARG;ADRA1D GO:0042493| response to drug PPARG;KCNJ11;CYP1A2;ABCC1;SLC6A4;ABCG2;ABCC2;ADRA1A;ABCB1;ABCC4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2C9;PPARG GO:0007507| heart development PPARG;RXRA;CACNA1C GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007623| circadian rhythm NCOA2;SLC6A4 7481:[DB07863 DB01307] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;INSR GO:0032869| cellular response to insulin stimulus INSR;PPARG GO:0042593| glucose homeostasis INSR;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;INSR 7482:[DB07863 DB01571] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;PPARG GO:0007165| signal transduction PPARG;OPRD1;OPRM1;OPRK1 7483:[DB07863 DB00353] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2B;DRD1;PPARG GO:0007507| heart development HTR2B;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2B;DRD1;PPARG GO:0007165| signal transduction PPARG;DRD1;HTR2B 7484:[DB07863 DB08820] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug ABCB1;PPARG 7485:[DB07863 DB00324] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR3C1;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0006351| transcription, DNA-dependent NCOA2;NR3C1;PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0007165| signal transduction PPARG;NR3C1 7486:[DB07863 DB04938] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;ESR1;PPARG;RXRA GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PPARG;RXRA;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;ESR1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;ESR1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG;CYP2C9 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007165| signal transduction PPARG;ESR1 7487:[DB07863 DB13961] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes PPARG common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARD;RXRA;NFKB2;PPARA;PPARG;SREBF1;NFKB1 GO:0045087| innate immune response NFKB1;PPARG;NFKB2 GO:0007507| heart development PPARD;RXRA;PPARA;PPARG;CACNA1C GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA;PTGS2;PPARD;DGAT2;SREBF1 GO:0035902| response to immobilization stress PPARG GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;SREBF1;PPARA;PPARG;RXRA;NFKB2;NCOA2 GO:0071300| cellular response to retinoic acid PPARG GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA;SREBF1 GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARA;PPARG;RXRA GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0006351| transcription, DNA-dependent NFKB1;SREBF1;PPARG;PPARA;RXRA;NFKB2;PPARD;NCOA2 GO:0007623| circadian rhythm NCOA2;SREBF1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG;RXRA;SREBF1;NFKB1 GO:0008203| cholesterol metabolic process SREBF1;RXRA;PPARD GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG;RXRA;PPARD GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0050872| white fat cell differentiation PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A PPARG;PPARD GO:1904706| PPARG GO:0030522| intracellular receptor mediated signaling pathway PPARD;NCOA2;PPARA;SREBF1 GO:0071455| cellular response to hyperoxia PPARG GO:0032922| circadian regulation of gene expression PPARA;NCOA2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0030224| monocyte differentiation PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0042493| response to drug SREBF1;PPARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARD;NCOA2;PPARG;PPARA;NFKB2;RXRA;SREBF1;NFKB1 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG;RXRA;PPARD;NFKB1;SREBF1 GO:0007165| signal transduction NFKB1;FFAR4;PPARG;NFKB2 GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0032870| cellular response to hormone stimulus FFAR4;NCOA2 GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0033993| response to lipid SREBF1;PPARG GO:0043010| camera-type eye development RXRA;CACNA1C GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0032869| cellular response to insulin stimulus PPARG;SREBF1 GO:0060694| regulation of cholesterol transporter activity PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;FFAR4 GO:1905461| PPARG GO:0007566| embryo implantation RXRA;PTGS2;PPARD GO:0019216| regulation of lipid metabolic process PPARA;PPARG;RXRA;NCOA2 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process NCOA2;PPARA;PPARG;NFKB2 GO:0007584| response to nutrient PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0010033| response to organic substance PPARG;PPARD;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0045892| negative regulation of transcription, DNA-dependent NFKB1;PPARG;NCOA2;PPARD GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0031000| response to caffeine PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARD;PPARG GO:0001890| placenta development PPARD;PPARG;RXRA GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound SREBF1;PTGS2;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA 7488:[DB07863 DB00261] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;PDE3A;PPARG GO:0006629| lipid metabolic process PDE3A;CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0007165| signal transduction PDE3A;PPARG GO:0007186| G-protein coupled receptor signaling pathway PDE3A;PPARG 7489:[DB07863 DB00444] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0042493| response to drug PPARG;ABCC6;ABCG2 GO:0043065| positive regulation of apoptotic process PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9 GO:0048511| rhythmic process TOP2A;PPARG;NCOA2 7490:[DB07863 DB01098] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;ABCC4 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1B3;SLCO1B1;RXRA;ABCB11;SLCO1A2;NCOA2 GO:0010033| response to organic substance PPARG;ABCC4 GO:0007584| response to nutrient PPARG;HMGCR GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;HMGCR;NCOA2 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0042493| response to drug PPARG;ABCC1;ABCG2;ABCC2;ABCC4 GO:0008203| cholesterol metabolic process RXRA;HMGCR GO:0006629| lipid metabolic process HMGCR;CYP3A4;CYP2C9;PPARG 7491:[DB07863 DB01236] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug MT-ND1;CYP2E1;PPARG;GABRG3 GO:0007165| signal transduction GABRP;GABRA6;PPARG;GABRD;GABRA5;GABRB1;GABRQ;GABRE;GABRB3;ATP2C1;GRIA1 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0014070| response to organic cyclic compound PPARG;MT-ND1 7492:[DB07863 DB09481] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0042493| response to drug GRIN2A;PPARG GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;PPARG;RXRA 7493:[DB07863 DB13954] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes NCOA2 common pathways GO:0045475| locomotor rhythm NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2;UGT1A1 GO:1904017| NCOA2 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process NCOA2;PPARG GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;BECN1;CYP1B1;GPER1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1;PPARG GO:0015721| bile acid and bile salt transport SLCO1B3;RXRA;SLCO1B1;NCOA2;SLCO1A2;SLCO1C1;ALB;SLCO2B1 GO:0001890| placenta development RXRA;PPARG;HSD17B2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPER1 GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 GO:0007165| signal transduction ESR2;CHRNA4;GPER1;ESR1;PPARG;NR1I2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RXRA GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;RXRA;NR1I2;NCOA2;ESR2;ESRRG GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;PPARG;UGT1A1;BECN1;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;ESR1;ESR2;ESRRG GO:0001701| in utero embryonic development RXRA;HSD17B2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1;NR1I2;RXRA;ESRRG;ESR2 GO:1904706| GPER1;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0032922| circadian regulation of gene expression NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0010906| regulation of glucose metabolic process NCOA2 GO:0016032| viral reproduction BECN1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0032526| response to retinoic acid RXRA;PPARG;HSD17B2 GO:0006351| transcription, DNA-dependent ESR2;ESRRG;ESR1;PPARG;RXRA;NR1I2;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1;NR1I2;RXRA;GPER1;ESRRG;ESR2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1;RXRA GO:0007623| circadian rhythm NCOA2 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0045087| innate immune response GPER1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1;PPARG;RXRA;NCOA2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP1A2;HSD17B2;CYP3A4;PPARG;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ESR1;NR1I2;RXRA;NCOA2;ESR2;GPER1;ESRRG GO:0043065| positive regulation of apoptotic process CYP1B1;GPER1;PPARG 7494:[DB07863 DB00075] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CD3E;PPARG GO:0007165| signal transduction FCGR1A;FCGR2C;FCGR2B;PPARG GO:0007584| response to nutrient CD3E;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;CD3D;RXRA GO:0045087| innate immune response C1QA;FCGR1A;C1R;C1QB;PPARG;C1S;C1QC GO:0016032| viral reproduction CD247;RXRA;FCGR2B GO:0051289| protein homotetramerization CD247;RXRA 7495:[DB07863 DB09063] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG GO:0042493| response to drug ABCB1;PPARG GO:0007165| signal transduction ALK;PPARG 7496:[DB07863 DB00514] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0008217| regulation of blood pressure PPARG;CYBA GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 GO:0007584| response to nutrient PPARG;CYBB;SLC6A4 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0007165| signal transduction CHRNB4;PPARG;OPRD1;CHRNB2;OPRM1;OPRK1;CHRNA7;RAC2;CHRNA2;CHRNA4;CHRNA3 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PPARG;RAC1;RAC2;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NCF1;RXRA GO:0042493| response to drug CYBB;PPARG;CYP2E1;SLC6A2;CYBA;SLC6A4 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0043065| positive regulation of apoptotic process PPARG;RAC1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;CYP2C9;PPARG GO:0045087| innate immune response CYBA;NCF2;CYBB;NCF1;PPARG GO:0007623| circadian rhythm NCOA2;SLC6A4 7497:[DB07863 DB01275] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 7498:[DB07863 DB01327] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0010033| response to organic substance PPARG;ABCC4 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0014070| response to organic cyclic compound PPARG;ABCC4 GO:0007165| signal transduction IL15;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IL15 GO:0007186| G-protein coupled receptor signaling pathway IL2;PPARG GO:0042493| response to drug ABCC4;PPARG GO:0006629| lipid metabolic process PON1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;IL2 GO:0048469| cell maturation IL15;PPARG GO:0008203| cholesterol metabolic process PON1;RXRA 7499:[DB07863 DB00342] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0042493| response to drug ABCB1;PPARG GO:0007165| signal transduction CHRM5;CHRM3;HRH1;PPARG;CHRM1;CHRM2;CHRM4 GO:0007186| G-protein coupled receptor signaling pathway CHRM4;CHRM5;HRH1;CHRM3;CHRM1;PPARG;CHRM2 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 7500:[DB07863 DB00398] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;SLCO1B1;RXRA GO:0008285| negative regulation of cell proliferation PPARG;RAF1 GO:0010033| response to organic substance ABCC4;PPARG;UGT1A1;CYP1A2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0043627| response to estrogen stimulus ABCC2;PDGFRB;PPARG GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;PPARG;PDGFRB;ABCC4 GO:0006919| activation of caspase activity RET;PPARG GO:0033993| response to lipid PDGFRB;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;ABCC2 GO:0031100| organ regeneration UGT1A1;FLT3;PPARG GO:0007165| signal transduction RAF1;PDGFRB;RALBP1;PPARG;RET;BRAF;KIT GO:0019216| regulation of lipid metabolic process PPARG;RXRA;UGT1A9;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway PDGFRB;PPARG GO:0016032| viral reproduction KDR;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0001701| in utero embryonic development RXRA;FGFR1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;RET GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;FGFR1 GO:0042493| response to drug ABCC4;RET;ABCB1;ABCC2;ABCG2;CYP1A2;UGT1A1;PPARG GO:0071300| cellular response to retinoic acid PPARG;RET GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;RAF1 GO:0043065| positive regulation of apoptotic process PDGFRB;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;PPARG;CYP2C9;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;FGFR1;PPARG;RXRA GO:0007507| heart development RAF1;RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;PPARG;FGFR1;RXRA GO:0032526| response to retinoic acid RXRA;PDGFRB;PPARG GO:0048469| cell maturation PPARG;FGFR1 7501:[DB07863 DB09034] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0032870| cellular response to hormone stimulus HCRTR1;HCRTR2;NCOA2 GO:0007165| signal transduction HCRTR1;HCRTR2;PPARG GO:0007186| G-protein coupled receptor signaling pathway HCRTR2;HCRTR1;PPARG 7502:[DB07863 DB01242] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01242|Clomipramine SLC6A4;HTR2A;HTR2B;HTR2C;SLC6A2;GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A4;HTR2C;HTR2B;SLC6A2;CYP1A2;HTR2A;PPARG GO:1904706| PPARG;GSTP1 GO:0016032| viral reproduction HTR2A;RXRA GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0007507| heart development HTR2B;RXRA;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG;CYP1A2 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance PPARG;CYP1A2;SLC6A4 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0045600| positive regulation of fat cell differentiation HTR2C;HTR2A;PPARG GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0032869| cellular response to insulin stimulus GSTP1;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2B;HTR2C;HTR2A;PPARG GO:0007165| signal transduction PPARG;HTR2A;HTR2C;HTR2B GO:0031100| organ regeneration GSTP1;PPARG 7503:[DB07863 DB00470] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process PTGS1;CYP3A4;CYP2C9;PPARG GO:0043065| positive regulation of apoptotic process PPARG;CNR1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;PPARG GO:0007165| signal transduction PPARG;CNR1;CNR2 GO:0042593| glucose homeostasis PPARG;CNR1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007186| G-protein coupled receptor signaling pathway CNR2;PPARG;CNR1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;CNR1;NCOA2 GO:0007584| response to nutrient CNR1;PPARG GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG 7504:[DB07863 DB00559] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways GO:0007165| signal transduction EDNRB;PPARG;EDNRA GO:0007186| G-protein coupled receptor signaling pathway EDNRB;EDNRA;PPARG GO:0008217| regulation of blood pressure EDNRB;EDNRA;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 GO:0014070| response to organic cyclic compound PPARG;EDNRB GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;EDNRB GO:0007507| heart development RXRA;PPARG;EDNRA GO:0001701| in utero embryonic development RXRA;EDNRA 7505:[DB07863 DB00823] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0007165| signal transduction PGR;ESR1;PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;ESR1;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RXRA;ESR1;PPARG;NCOA2 GO:0006351| transcription, DNA-dependent PGR;PPARG;ESR1;RXRA;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;ESR1;PPARG;PGR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;ESR1;PGR GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent PGR;ESR1;PPARG;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1;RXRA 7506:[DB07863 DB01154] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways GO:0042493| response to drug KCNJ11;CYP2E1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4 GO:0007507| heart development KCNJ8;RXRA;PPARG 7507:[DB07863 DB01356] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:0007165| signal transduction PPARG;IMPA2;IMPA1 GO:0048511| rhythmic process PPARG;NCOA2;GSK3B GO:0007623| circadian rhythm GSK3B;NCOA2 7508:[DB07863 DB06779] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0030855| epithelial cell differentiation VEGFA;PPARG GO:0007584| response to nutrient PPARG;SERPINC1 GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;RXRA GO:0048469| cell maturation PPARG;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;VEGFA;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;NCOA2;PPARG;RXRA GO:0030224| monocyte differentiation VEGFA;PPARG GO:0001701| in utero embryonic development RXRA;VEGFA 7509:[DB07863 DB06702] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway CHRM4;CHRM3;CHRM5;CHRM2;CHRM1;PPARG GO:0007165| signal transduction CHRM4;CHRM5;CHRM3;PPARG;CHRM1;CHRM2 7510:[DB07863 DB00351] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;PPARG;RXRA;NCOA2;NR3C1 GO:0006351| transcription, DNA-dependent NCOA2;NR3C1;RXRA;PPARG;PGR GO:0043401| steroid hormone mediated signaling pathway PGR;NR3C1;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PGR;NR3C1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent PGR;RXRA;PPARG;NCOA2;NR3C1 GO:0042493| response to drug PPARG;ABCB1 GO:0007165| signal transduction PGR;NR3C1;PPARG 7511:[DB07863 DB11672] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes PPARG common pathways GO:0031000| response to caffeine PPARG GO:0008217| regulation of blood pressure PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;VDR GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation PPARG;VDR GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0048511| rhythmic process PPARG;NCOA2 GO:0007584| response to nutrient PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;RXRA GO:0019395| fatty acid oxidation PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation GSTA1;CBR1;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction PPARG;VDR GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration GSTP1;PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;GSTP1 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2 GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1904706| PPARG;GSTP1 GO:0033189| response to vitamin A PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;VDR GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0030224| monocyte differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0006355| regulation of transcription, DNA-dependent VDR;PPARG;RXRA;NCOA2 GO:0042493| response to drug PPARG;CYP1A2;ABCB1 GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;PPARG;RXRA;NCOA2 GO:0045087| innate immune response PPARG GO:0009612| response to mechanical stimulus PPARG GO:0009409| response to cold PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;NCOA2;RXRA;PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;VDR GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;VDR GO:0032526| response to retinoic acid PPARG;RXRA GO:0048469| cell maturation PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG 7512:[DB07863 DB00668] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TNF;RXRA;NCOA2 GO:0009409| response to cold ADRB2;PPARG;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;TNF;ADRB2;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;TNF GO:0045893| positive regulation of transcription, DNA-dependent RXRA;TNF;PPARG GO:0042493| response to drug MAOB;COMT;PPARG;ADRA1A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0045994| positive regulation of translational initiation by iron RXRA;TNF GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRB1;ADRA2A;ADRA1B;ADRA1D;PPARG;ADRB2;ADRA2B GO:0007165| signal transduction ADRA1D;PPARG;ADRA2B;ADRB2;ADRB1;ADRA1A;ADRA1B;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0048662| negative regulation of smooth muscle cell proliferation COMT;PPARG GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0014070| response to organic cyclic compound PPARG;COMT GO:0006919| activation of caspase activity PPARG;TNF GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;TNF GO:0010033| response to organic substance PPARG;TNF GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0043627| response to estrogen stimulus PPARG;COMT 7513:[DB07863 DB09295] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PPARG;PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0010033| response to organic substance PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0007566| embryo implantation RXRA;PTGS2 7514:[DB07863 DB00328] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes PPARG common pathways GO:0001890| placenta development RXRA;PPARG GO:0019395| fatty acid oxidation PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;SLCO1B1;NCOA2;SLCO1A2;ABCC3;ALB;SLC10A1 GO:0045600| positive regulation of fat cell differentiation PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance ABCC4;PPARG;UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0031000| response to caffeine PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0007584| response to nutrient UGT1A1;AKR1C3;PPARG GO:0048511| rhythmic process PPARA;PPARG;NCOA2 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2;UGT1A1;ABCC4 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2;ABCC2 GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0033993| response to lipid PPARG GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction PPARG;PTGDR2 GO:0019216| regulation of lipid metabolic process PPARA;PPARG;RXRA;UGT1A9;NCOA2 GO:0007566| embryo implantation PTGS2;RXRA GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;PPARG;AKR1C3 GO:1905461| PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0032869| cellular response to insulin stimulus PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0016032| viral reproduction SLC10A1;RXRA GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0030522| intracellular receptor mediated signaling pathway NCOA2;PPARA GO:0071455| cellular response to hyperoxia PPARG GO:0032922| circadian regulation of gene expression NCOA2;PPARA GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A PPARG GO:1904706| PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA;RXRA GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0050872| white fat cell differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG;RXRA GO:0071379| cellular response to prostaglandin stimulus PPARG;AKR1C3 GO:0042493| response to drug UGT1A1;PTGS2;ABCC6;ABCC1;PPARG;ABCB1;ABCC4;ABCC2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;PPARA GO:0061614| PPARG GO:0030224| monocyte differentiation PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARA;PPARG;RXRA GO:0042594| response to starvation PPARG;UGT1A1 GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process PTGS2;PPARG;CYP2C9;PPARA;UGT2B7;PTGS1;PLA2G2A GO:0035902| response to immobilization stress PPARG GO:0042953| lipoprotein transport PPARG GO:0007507| heart development RXRA;PPARA;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;RXRA;NCOA2 GO:0045165| cell fate commitment PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter GLO1;PPARG;RXRA GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA;RXRA GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;PPARA;RXRA GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA 7515:[DB07863 DB00394] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;NR3C1;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0007165| signal transduction PPARG;NR3C1 7516:[DB07863 DB00286] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A2;COMT;ABCC4 GO:0010033| response to organic substance ABCC4;CYP1A2;PPARG GO:0043627| response to estrogen stimulus COMT;ESR1;PPARG;ABCC2 GO:0015721| bile acid and bile salt transport SLCO1B1;SLC51A;RXRA;SLCO1B3;SLCO1C1;ABCC3;SLCO1A2;NCOA2;SLCO2B1;SLC51B;SLC10A1 GO:0007165| signal transduction ESR1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1;RXRA GO:0042493| response to drug ABCB1;ABCC4;ABCG2;ABCC2;COMT;CYP1A2;ABCC1;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;ESR1 GO:0016032| viral reproduction SLC10A1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006351| transcription, DNA-dependent NCOA2;ESR1;PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2 7517:[DB07863 DB00811] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0032869| cellular response to insulin stimulus ENPP1;PPARG GO:0051289| protein homotetramerization IMPDH2;RXRA GO:0007623| circadian rhythm NCOA2;IMPDH2 GO:0030308| negative regulation of cell growth ENPP1;PPARG 7518:[DB07863 DB00577] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLC10A2 7519:[DB07863 DB01149] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0015721| bile acid and bile salt transport NCOA2;SLCO1B3;ABCB11;RXRA;SLCO2B1 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;HTR2C GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0010033| response to organic substance PPARG;SLC6A4 GO:0007584| response to nutrient SLC6A4;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2A;PPARG;HTR1A;ADRA1A;ADRA2A;ADRA1B;HTR2C GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0007165| signal transduction PPARG;HTR1A;HTR2A;ADRA2A;ADRA1B;HTR2C;ADRA1A GO:0042493| response to drug PPARG;HTR2A;SLC6A2;SLC6A4;HTR2C;SLC6A3;ABCB1;ADRA1A GO:0016032| viral reproduction RXRA;HTR2A GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG 7520:[DB07863 DB11582] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TNFSF11;RXRA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0042493| response to drug GABRG3;PPARG GO:0007165| signal transduction GABRB3;GABRA5;GABRB1;GABRQ;GABRE;GABRP;PPARG;GABRA6;GABRD 7521:[DB07863 DB00202] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM3;CHRM2;CHRM1;PPARG GO:0007165| signal transduction CHRNA10;CHRNA7;CHRM3;PPARG;CHRM1;CHRM2 GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0007584| response to nutrient PPARG;BCHE GO:0042493| response to drug PPARG;BCHE 7522:[DB07863 DB06697] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4 7523:[DB07863 DB01095] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process UGT2B7;CYP2D6;HMGCR;CYP3A4;PPARG;CYP2C9 GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0008203| cholesterol metabolic process HMGCR;RXRA GO:0033189| response to vitamin A CYP1A1;PPARG GO:0042493| response to drug UGT1A1;CYP1A1;PPARG;ABCC2 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;ABCC2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0031100| organ regeneration PPARG;UGT1A1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;HMGCR;NCOA2 GO:0015721| bile acid and bile salt transport SLCO2B1;NCOA2;RXRA;SLCO1B1;SLCO1B3 GO:0010033| response to organic substance UGT1A1;PPARG;CYP1A1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0007584| response to nutrient UGT1A1;HMGCR;PPARG GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;PPARG 7524:[DB07863 DB14063] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process PPARG;CYP3A4 7525:[DB07863 DB04953] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0019216| regulation of lipid metabolic process PPARG;RXRA;UGT1A9;NCOA2 GO:0010033| response to organic substance PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug UGT1A1;PPARG 7526:[DB07863 DB00320] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2B;ADRA2A;HTR1B;PPARG;HTR1D GO:0007165| signal transduction HTR1B;HTR2B;ADRA2A;HTR1D;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007507| heart development PPARG;RXRA;HTR2B GO:0042493| response to drug HTR2B;ABCB1;HTR1B;PPARG 7527:[DB07863 DB00368] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent POU5F1;PPARG;RXRA;NCOA2 GO:0042493| response to drug SLC6A2;PPARG;ADRA1A GO:0006351| transcription, DNA-dependent POU5F1;PPARG;RXRA;NCOA2 GO:0009409| response to cold PPARG;ADRB2;ADRB1;ADRB3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter POU5F1;NCOA2;RXRA;ADRB2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter POU5F1;NCOA2;PPARG;RXRA GO:0060965| negative regulation of gene silencing by miRNA POU5F1;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA2C;PPARG;ADRB2;ADRA2B;ADRA1D;ADRA2A;ADRA1B;ADRB3;ADRB1;ADRA1A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA2A;ADRA1B GO:0007165| signal transduction ADRA1A;ADRB1;ADRB3;ADRA2A;ADRA1B;ADRA1D;ADRA2B;ADRB2;ADRA2C;PPARG 7528:[DB07863 DB00074] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0007165| signal transduction FCGR1A;IL2RB;FCGR2C;FCGR2B;PPARG GO:0045087| innate immune response C1R;C1QB;C1QC;C1S;PPARG;C1QA;FCGR1A GO:0016032| viral reproduction FCGR2B;RXRA;IL2RB 7529:[DB07863 DB00755] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes RXRA common pathways GO:0045994| positive regulation of translational initiation by iron RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0015909| long-chain fatty acid transport LCN1;PPARG GO:0007186| G-protein coupled receptor signaling pathway GPRC5A;PPARG GO:0060038| cardiac muscle cell proliferation RXRA GO:0019216| regulation of lipid metabolic process NCOA2;CYP4A11;RXRA;PPARG;CYP1A1 GO:0007566| embryo implantation RXRA GO:0001893| maternal placenta development RXRA GO:0007165| signal transduction PPARG;CRABP1;GPRC5A;CRABP2;HPGDS;RARA;RARB GO:0042593| glucose homeostasis PDK4;RBP4;PPARG GO:0043010| camera-type eye development RARG;ALDH1A2;RXRA;CYP1A1 GO:0060528| secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development RXRA GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0055012| ventricular cardiac muscle cell differentiation RXRA;RARA;RARB GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;RARA;NR0B1 GO:0010033| response to organic substance CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation RARG;ALDH1A2;RARB;RARA;PPARG;RARRES1 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0001890| placenta development PPARG;RXRA GO:0055010| ventricular cardiac muscle tissue morphogenesis RXRA GO:0032526| response to retinoic acid RBP4;RARG;RARA;PPARG;RXRA GO:0006351| transcription, DNA-dependent RARG;RXRG;RARB;RARA;NR0B1;RXRA;RXRB;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RARA;NR0B1;RARB;RARG;RXRG;RXRB;RXRA;PPARG GO:0008203| cholesterol metabolic process RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0007507| heart development RBP4;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;RARG;RARB;NR0B1;RARA GO:1901522| RXRA;RXRG GO:0035902| response to immobilization stress CYP1A1;PPARG;NR0B1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;HPGDS GO:0042594| response to starvation PPARG;PDK4 GO:0019048| virus-host interaction RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARB;RARA;RXRG;RARG;NCOA2;PPARG;RXRA;RXRB GO:0043065| positive regulation of apoptotic process PPARG;RARB;ALDH1A2;RARG GO:0071300| cellular response to retinoic acid CYP26B1;PPARG;RARA;RARG;ALDH1A2 GO:0048384| retinoic acid receptor signaling pathway CYP26B1;RXRA;RXRB;RARB;RARA;RARG;ALDH1A2;RXRG GO:0006766| vitamin metabolic process RXRA;CYP26B1;CYP26C1;CYP26A1 GO:0006355| regulation of transcription, DNA-dependent RXRB;RXRA;PPARG;NCOA2;RARG;RXRG;NR0B1;RARA;RARB;CRABP2 GO:0042493| response to drug CYP1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;RARA GO:0001701| in utero embryonic development RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;RXRB;PPARG;RARG;RXRG;RARB;NR0B1;RARA GO:0033189| response to vitamin A RARA;ALDH1A2;PPARG;CYP1A1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA GO:0051289| protein homotetramerization RXRG;RXRA GO:0030522| intracellular receptor mediated signaling pathway RXRB;NCOA2;NR0B1 GO:0010906| regulation of glucose metabolic process NCOA2;PDK4 GO:0016032| viral reproduction RXRA 7530:[DB07863 DB03128] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM4;CHRM3;CHRM2;CHRM1;PPARG GO:0007165| signal transduction CHRM3;CHRM2;CHRM1;PPARG;CHRM4;CHRNA7 7531:[DB07863 DB01306] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01306|Insulin Aspart INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;INSR;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent INSR;RXRA;PPARG GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG GO:0032869| cellular response to insulin stimulus INSR;PPARG GO:0042593| glucose homeostasis PPARG;INSR 7532:[DB07863 DB05773] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;ERBB2 GO:0042493| response to drug ABCB1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;PPARG;RXRA GO:0006351| transcription, DNA-dependent ERBB2;NCOA2;RXRA;PPARG GO:0007507| heart development ERBB2;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007165| signal transduction PPARG;ERBB2 7533:[DB07863 DB01614] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA GO:0042493| response to drug DRD1;ADRA1A;DRD2;PPARG;HTR2A GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0016032| viral reproduction RXRA;HTR2A GO:0007186| G-protein coupled receptor signaling pathway DRD1;ADRA1B;DRD2;ADRA1A;HTR2A;HTR1A;PPARG GO:0007165| signal transduction HTR2A;PPARG;HTR1A;DRD1;ADRA1B;DRD2;ADRA1A GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB 7534:[DB07863 DB13151] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0007623| circadian rhythm F7;NCOA2 GO:0045087| innate immune response PPARG;FGA;FGB GO:0014070| response to organic cyclic compound PPARG;F7 GO:0043627| response to estrogen stimulus F7;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;F2 GO:0007165| signal transduction FGB;FGA;PPARG GO:0031100| organ regeneration PPARG;F7 7535:[DB07863 DB00475] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;GABRA6;GABRD;GABRP;GABRE;GABRB1;GABRA5;GABRQ;GABRB3 GO:0042493| response to drug PPARG;GABRG3 GO:0006629| lipid metabolic process PPARG;CYP3A4 7536:[DB07863 DB01431] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2;PGR GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1;RXRA GO:0006351| transcription, DNA-dependent PGR;NCOA2;RXRA;ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;ESR1;PGR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1;RXRA;PGR GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1;RXRA;PGR GO:0007165| signal transduction PGR;ESR1;PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG 7537:[DB07863 DB01382] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0042493| response to drug PPARG;ABCC8 GO:0016525| negative regulation of angiogenesis PPARG;ABCC8 GO:0007165| signal transduction ABCC8;PPARG 7538:[DB07863 DB08836] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1A2 GO:0008217| regulation of blood pressure PPARG;ACE 7539:[DB07863 DB00714] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0007507| heart development PPARG;RXRA;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;DRD3;RXRA;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;DRD3;NCOA2 GO:0042493| response to drug HTR1B;DRD2;HTR2B;HTR2C;DRD1;PPARG;DRD3;HTR2A GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0019216| regulation of lipid metabolic process RXRA;DRD3;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway DRD1;HTR2B;HTR2C;ADRA2A;DRD5;DRD2;HTR1B;ADRA2B;HTR2A;DRD3;DRD4;PPARG;HTR1A;ADRA2C;HTR1D GO:0007165| signal transduction HTR2C;HTR2B;ADRA2A;DRD1;HTR1B;DRD2;DRD5;HTR1A;PPARG;DRD4;ADRA2C;HTR2A;ADRA2B;DRD3;HTR1D GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0048511| rhythmic process PPARG;DRD4;NCOA2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C 7540:[DB07863 DB09099] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation PPARG;SSTR1;SSTR3;SSTR2 GO:0007584| response to nutrient SSTR2;SSTR1;PPARG GO:0008285| negative regulation of cell proliferation SSTR4;SSTR5;SSTR2;SSTR3;SSTR1;PPARG GO:0042593| glucose homeostasis PPARG;SSTR5 GO:0007165| signal transduction SSTR3;SSTR1;PPARG;SSTR2;SSTR4;SSTR5 GO:0007186| G-protein coupled receptor signaling pathway PPARG;SSTR1;SSTR3;SSTR2;SSTR5;SSTR4 7541:[DB07863 DB00176] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes common pathways GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;CYP1A2;CYP2D6 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug PPARG;CYP1A1;CYP2E1;CYP1A2;SLC6A4;ABCB1 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;CYP1A1;PPARG GO:0010033| response to organic substance SLC6A4;CYP1A2;PPARG;CYP1A1 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 7542:[DB07863 DB06822] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0009612| response to mechanical stimulus PPARG;CXCL12 GO:0007584| response to nutrient PPARG;SERPINC1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CXCL12 GO:0007165| signal transduction PPARG;CXCL12 GO:0031100| organ regeneration CXCL12;PPARG 7543:[DB07863 DB00200] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0008203| cholesterol metabolic process RXRA;CUBN GO:0006629| lipid metabolic process CUBN;PPARG GO:0042953| lipoprotein transport PPARG;CUBN 7544:[DB07863 DB09564] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09564|Insulin Degludec INSR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG GO:0032869| cellular response to insulin stimulus PPARG;INSR GO:0042593| glucose homeostasis INSR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;INSR;NCOA2 7545:[DB07863 DB14517] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway APP;PPARG GO:0008285| negative regulation of cell proliferation PPARG;APP GO:0008217| regulation of blood pressure PPARG;ATP1A1 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0045087| innate immune response PPARG;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;APP;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;APP GO:0008203| cholesterol metabolic process RXRA;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0042493| response to drug PPARG;ATP1A1 7546:[DB07863 DB01212] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB 7547:[DB07863 DB00762] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes common pathways GO:0019216| regulation of lipid metabolic process NCOA2;UGT1A9;RXRA;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1;NCOA2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B1;ALB GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0048511| rhythmic process NCOA2;TOP1;PPARG GO:0007584| response to nutrient BCHE;UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation BCHE;PPARG GO:0007623| circadian rhythm NCOA2;TOP1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0042493| response to drug PPARG;TOP1;ABCC1;BCHE;UGT1A1;ABCC2;ABCG2;ABCB1 GO:0032922| circadian regulation of gene expression NCOA2;TOP1 GO:0016032| viral reproduction RXRA;TOP1 7548:[DB07863 DB00243] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG 7549:[DB07863 DB00884] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0007566| embryo implantation PTGS2;RXRA GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0008203| cholesterol metabolic process RXRA;FDPS GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process FDPS;PPARG;PTGS2 GO:0042493| response to drug PTGS2;PPARG GO:0016032| viral reproduction RXRA;FDPS 7550:[DB07863 DB01056] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042493| response to drug PPARG;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0014070| response to organic cyclic compound PPARG;CYP1A2 7551:[DB07863 DB00555] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0031000| response to caffeine ADORA2A;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;ADORA2A;ADORA1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2A;ADORA2A;CHRM2;PPARG;ADORA1;CHRM1;CHRM3;HRH1;CHRM5;DRD1;OPRK1;ADRA2A;DRD5;CHRM4;ADRB1;DRD2;ADRA1A GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction ADRA1A;DRD2;ADRB1;HTR3A;CHRM4;DRD5;GABRB3;ADRA2A;DRD1;OPRK1;CHRM5;GABRE;GABRA5;GABRB1;CHRM3;HRH1;GABRQ;PPARG;GABRA6;CHRM1;ADORA1;GABRD;GABRP;HTR2A;CHRM2;ADORA2A GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ADORA2A;RXRA GO:0042493| response to drug UGT1A1;PPARG;ADORA2A;HTR2A;ABCB1;ADRA1A;DRD2;GABRG3;DRD1 GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0009409| response to cold PPARG;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA GO:0042594| response to starvation UGT1A1;PPARG 7552:[DB07863 DB04896] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0010033| response to organic substance SLC6A4;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0042493| response to drug SLC6A4;GRIN2A;SLC6A2;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0043065| positive regulation of apoptotic process GRIN1;PPARG;GRIN2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 7553:[DB07863 DB01354] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction CHRNA7;GRIA2;CHRNA4;GABRA6;PPARG;GABRA5 7554:[DB07863 DB01255] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0007165| signal transduction TAAR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway TAAR1;PPARG 7555:[DB07863 DB01202] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug ABCB1;ABCC2;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0008217| regulation of blood pressure PPARG;CACNA1B GO:0043627| response to estrogen stimulus ABCC2;PPARG 7556:[DB07863 DB00344] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 GO:0042493| response to drug SLC6A2;PPARG;ABCB1;SLC6A4 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0006629| lipid metabolic process PPARG;CYP2D6 7557:[DB07863 DB00007] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;GNRHR GO:0007186| G-protein coupled receptor signaling pathway GNRHR;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7558:[DB07863 DB00455] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0007165| signal transduction PPARG;HRH1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;HRH1 GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0042493| response to drug PPARG;ABCB1 7559:[DB07863 DB13874] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways GO:0042493| response to drug PPARG;CYP1A2;UGT1A1;ABCG2;ABCB1 GO:0006629| lipid metabolic process UGT2B7;CYP2D6;CYP1A2;CYP3A4;CYP2C9;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0015721| bile acid and bile salt transport NCOA2;SLCO1B3;SLCO1B1;RXRA GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1;CYP1A2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0019216| regulation of lipid metabolic process PPARG;RXRA;UGT1A9;NCOA2 7560:[DB07863 DB01136] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG;GJA1 GO:0008217| regulation of blood pressure PTGS1;NPPB;PPARG GO:0007584| response to nutrient UGT1A1;VCAM1;PPARG GO:0030855| epithelial cell differentiation VEGFA;PPARG GO:0006919| activation of caspase activity XDH;PPARG GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;PPARG;CYP1A1 GO:0007165| signal transduction ADRB2;ADRA2B;ADRA2C;GJA1;PPARG;ADRA1D;ADRA2A;ADRA1B;HIF1A;ADRB1;ADRA1A GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;ADRA2A GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0042593| glucose homeostasis ADRA2A;ADRA1B;HIF1A;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;ADRA2B;ADRB2;PPARG;ADRA2C;ADRB1;ADRA1A;ADRA1B;ADRA2A GO:0016525| negative regulation of angiogenesis NPPB;PPARG GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0001701| in utero embryonic development RXRA;GJA1;VEGFA GO:0016032| viral reproduction RXRA;VCAM1 GO:0030224| monocyte differentiation PPARG;VEGFA GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;HIF1A GO:0042493| response to drug CYP2E1;CYP1A1;PPARG;UGT1A1;CYP1A2;ABCB1;ADRA1A GO:0006355| regulation of transcription, DNA-dependent HIF1A;NCOA2;PPARG;RXRA GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP1A2;CYP2D6;PTGS1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0007507| heart development GJA1;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;VEGFA GO:0009409| response to cold ADRB1;ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HIF1A;NCOA2;VEGFA;ADRB2;RXRA;PPARG GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;HIF1A GO:0048469| cell maturation PPARG;VEGFA GO:0032526| response to retinoic acid RXRA;PPARG;GJA1 GO:0030308| negative regulation of cell growth NPPB;GJA1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;RXRA;PPARG 7561:[DB07863 DB01621] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug DRD2;DRD1;HTR2A;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;RXRA;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0007165| signal transduction HTR1A;PPARG;HTR2A;DRD1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway DRD2;DRD1;PPARG;HTR1A;HTR2A 7562:[DB07863 DB00425] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0007165| signal transduction PPARG;GABRB3 GO:0042493| response to drug PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;CYP1A2;CYP2D6;PTGS1 GO:0035902| response to immobilization stress PPARG;CYP1A2 7563:[DB07863 DB11278] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0007165| signal transduction ADRA1A;ADRB1;ADRA2A;ADRA1B;ADRB3;ADRA1D;ADRA2C;PPARG;ADRA2B;ADRB2 GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;ADRB2;ADRA2B;ADRA2C;PPARG;ADRB1;ADRA1A;ADRB3;ADRA2A;ADRA1B GO:0042493| response to drug ADRA1A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RXRA;PPARG;NCOA2 GO:0009409| response to cold PPARG;ADRB2;ADRB1;ADRB3 7564:[DB07863 DB11979] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GNRHR GO:0007165| signal transduction PPARG;GNRHR GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 7565:[DB07863 DB07776] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESRRB;ESRRA;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent ESRRA;ESRRB;RXRA;PPARG;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;ESRRB;ESRRA GO:0030522| intracellular receptor mediated signaling pathway ESRRA;ESRRB;NCOA2 GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;ESRRA;ESRRB GO:0043401| steroid hormone mediated signaling pathway ESRRA;ESRRB;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;ESRRB;PPARG;RXRA;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;ESRRB;ESRRA GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 7566:[DB07863 DB00962] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0007165| signal transduction PPARG;TSPO GO:0042493| response to drug PPARG;TSPO GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;TSPO 7567:[DB07863 DB01026] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1I2;RXRA;NR1I3;NCOA2;AR GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP11A1;PPARG;CYP2C9;CYP3A4;CYP11B1;CYP1A2;CYP51A1;CYP2D6;UGT2B7 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;AR GO:0008203| cholesterol metabolic process CYP51A1;RXRA;CYP11A1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;RXRA;NR1I3;AR GO:0006351| transcription, DNA-dependent AR;PPARG;RXRA;NR1I2;NCOA2;NR1I3 GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NR1I3;NCOA2;AR GO:0033189| response to vitamin A CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter AR;RXRA;NR1I2;PPARG;NR1I3 GO:0001701| in utero embryonic development RXRA;AR GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;AR GO:0042493| response to drug ABCB1;PPARG;CYP1A1;UGT1A1;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent AR;NCOA2;NR1I3;RXRA;NR1I2;PPARG GO:0006766| vitamin metabolic process CYP26A1;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;CYP11B1;UGT1A1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0031100| organ regeneration UGT1A1;PPARG GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0007165| signal transduction AR;NR1I3;NR1I2;PPARG GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;SLCO1B1;RXRA;ABCB11 GO:0008285| negative regulation of cell proliferation CYP1B1;AR;PPARG GO:0010033| response to organic substance UGT1A1;CYP1A2;CYP1A1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I3;NR1I2;PPARG GO:0008217| regulation of blood pressure CYP4F2;CYP11B1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;UGT1A1;CYP1A2 7568:[DB07863 DB01203] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0007165| signal transduction PPARG;ADRB2;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG;ADRB1 GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;ADRB2;PPARG GO:0009409| response to cold ADRB1;ADRB2;PPARG 7569:[DB07863 DB01048] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0042594| response to starvation PPARG;UGT1A1 GO:0045087| innate immune response PPARG;HLA-B GO:0016032| viral reproduction HLA-B;RXRA GO:0042493| response to drug PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 7570:[DB07863 DB11090] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 7571:[DB07863 DB01097] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0007165| signal transduction PPARG;PTK2B GO:0048511| rhythmic process NCOA2;AHR;PPARG GO:0008285| negative regulation of cell proliferation PTK2B;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0031000| response to caffeine PPARG;DHODH GO:0045892| negative regulation of transcription, DNA-dependent PPARG;AHR;NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;DHODH GO:0045087| innate immune response PPARG;PTK2B GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP1A2 GO:0042594| response to starvation DHODH;PPARG GO:0035902| response to immobilization stress PTK2B;PPARG;CYP1A2 GO:0043065| positive regulation of apoptotic process PPARG;DHODH GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;AHR GO:0071300| cellular response to retinoic acid PTK2B;PPARG GO:0009612| response to mechanical stimulus PPARG;PTK2B GO:0006351| transcription, DNA-dependent NCOA2;AHR;RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;RXRA;PPARG GO:0030522| intracellular receptor mediated signaling pathway AHR;NCOA2 GO:0032922| circadian regulation of gene expression AHR;NCOA2 GO:0042493| response to drug ABCG2;PTK2B;DHODH;CYP1A2;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;AHR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;AHR 7572:[DB07863 DB00670] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00670|Pirenzepine CHRM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM1;PPARG GO:0007165| signal transduction PPARG;CHRM1 7573:[DB07863 DB01169] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity AKT1;PPARG GO:0016032| viral reproduction MAPK3;MAPK1;PML;RXRA;HDAC1 GO:0032922| circadian regulation of gene expression NCOA2;HDAC1;PML GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG;PML GO:0042752| regulation of circadian rhythm PPARG;PML GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;CCND1;RXRA;CDKN1A GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IKBKB;RXRA;HDAC1;MAPK1;AKT1;JUN GO:0006355| regulation of transcription, DNA-dependent NCOA2;JUN;MAPK1;RXRA;HDAC1;CCND1;PPARG;PML GO:0042493| response to drug HDAC1;CCND1;PPARG;CYP1A1;JUN;ABCC2;CDKN1A;ABCB1 GO:0048384| retinoic acid receptor signaling pathway RXRA;PML GO:0030224| monocyte differentiation JUN;PPARG GO:0009612| response to mechanical stimulus JUN;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PML;PPARG;IKBKB;RXRA;HDAC1;MAPK3;NCOA2;JUN;AKT1 GO:0043065| positive regulation of apoptotic process PPARG;AKT1;JUN;CYP1B1 GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0051974| negative regulation of telomerase activity PPARG;PML GO:0045165| cell fate commitment PPARG;PML GO:0000122| negative regulation of transcription from RNA polymerase II promoter CCND1;PPARG;RXRA;HDAC1;NCOA2 GO:0045087| innate immune response PPARG;PML;IKBKB GO:0007507| heart development MAPK1;RXRA;PPARG GO:0030308| negative regulation of cell growth PPARG;PML;CDKN1A GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;CDKN1A GO:0007623| circadian rhythm NCOA2;JUN GO:0006351| transcription, DNA-dependent PML;PPARG;CCND1;RXRA;HDAC1;MAPK1;MAPK3;NCOA2;JUN GO:0071380| cellular response to prostaglandin E stimulus PPARG;AKT1 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARG;AKT1 GO:0031000| response to caffeine HDAC1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent JUN;NCOA2;HDAC1;PML;PPARG GO:0008285| negative regulation of cell proliferation HDAC1;PML;PPARG;JUN;CDKN1A;CYP1B1 GO:0010033| response to organic substance CDKN1A;AKT1;JUN;CCND1;PPARG;CYP1A1 GO:0048511| rhythmic process NCOA2;HDAC1;PPARG;PML GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC1 GO:0043627| response to estrogen stimulus ABCC2;MAPK1;CCND1;PPARG GO:0014070| response to organic cyclic compound CDKN1A;JUN;CYP1A1;PPARG;CCND1 GO:0006919| activation of caspase activity PPARG;PML GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;JUN;ABCC2 GO:0031100| organ regeneration CCND1;PPARG;CDKN1A GO:0042593| glucose homeostasis PPARG;AKT1 GO:0001893| maternal placenta development AKT1;RXRA GO:0007165| signal transduction TXNRD1;MAPK1;AKT1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1;TXNRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;AKT1 GO:0032869| cellular response to insulin stimulus AKT1;PPARG 7574:[DB07863 DB00831] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0042493| response to drug PPARG;CYP1A2;DRD2;ADRA1A;ABCB1 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RXRA;PPARG;NCOA2 GO:0055010| ventricular cardiac muscle tissue morphogenesis RXRA;TNNC1 GO:0010033| response to organic substance CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0006919| activation of caspase activity XDH;PPARG GO:0007165| signal transduction PPARG;ADRA1A;DRD2 GO:0007186| G-protein coupled receptor signaling pathway DRD2;ADRA1A;CALM1;PPARG 7575:[DB07863 DB09225] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;PPARG;DRD1;HTR6;DRD5;HTR7;DRD2 GO:0007165| signal transduction HTR2A;PPARG;DRD5;HTR7;DRD2;DRD1;HTR6 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance SLC6A4;CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0007623| circadian rhythm NCOA2;HTR7;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2 GO:0042493| response to drug PPARG;HTR2A;CYP1A2;SLC6A2;SLC6A4;DRD1;DRD2 GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0016032| viral reproduction RXRA;HTR2A 7576:[DB07863 DB09237] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007507| heart development RXRA;PPARG;CACNA1C GO:0007623| circadian rhythm NCOA2;NOS2 GO:0001701| in utero embryonic development NOS3;RXRA GO:0043010| camera-type eye development CACNA1C;RXRA GO:0008217| regulation of blood pressure PPARG;NOS3 GO:0008285| negative regulation of cell proliferation PPARG;NOS3 7577:[DB07863 DB00570] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0009612| response to mechanical stimulus JUN;PPARG GO:0043065| positive regulation of apoptotic process JUN;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;JUN;PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;JUN;PPARG;RXRA GO:0007623| circadian rhythm NCOA2;JUN GO:0030224| monocyte differentiation PPARG;JUN GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;JUN GO:0042493| response to drug ABCC2;ABCB1;PPARG;ABCC1;ABCC6;JUN GO:0006355| regulation of transcription, DNA-dependent NCOA2;JUN;PPARG;RXRA GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2;JUN GO:0008285| negative regulation of cell proliferation JUN;PPARG GO:0010033| response to organic substance PPARG;JUN GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;JUN GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0015721| bile acid and bile salt transport NCOA2;SLCO1B1;RXRA;ABCB11 GO:0014070| response to organic cyclic compound PPARG;JUN 7578:[DB07863 DB04348] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;FABP6 GO:0010033| response to organic substance ABCC4;PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0015721| bile acid and bile salt transport SLCO1B3;FABP6;SLC51A;SLCO1B1;RXRA;ABCB11;ABCC3;SLCO1A2;NR1H4;SLCO1C1;NCOA2;SLCO2B1;SLC51B;SLC10A2;SLC10A1 GO:0014070| response to organic cyclic compound PPARG;ABCC4 GO:0007165| signal transduction PPARG;NR1H4 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0042593| glucose homeostasis NR1H4;PPARG;SLC16A1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1H4;RXRA;PPARG GO:0016032| viral reproduction SLC10A1;RXRA GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1H4 GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;NR1H4 GO:0042493| response to drug PPARG;ABCC1;ABCC2;ABCG2;ABCC4;ABCB1 GO:0006629| lipid metabolic process SLC16A1;PPARG;CEL;FABP6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR1H4 GO:0045087| innate immune response NR1H4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;NCOA2;PPARG;RXRA GO:0006351| transcription, DNA-dependent PPARG;RXRA;NR1H4;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR1H4;RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NR1H4 7579:[DB07863 DB00463] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction CHRNA7;GABRB3;CHRNA4;GRIA2;GABRP;GABRD;PPARG;GABRA6;GABRQ;GABRA5;GABRB1;GABRE GO:0042493| response to drug PPARG;GABRG3 7580:[DB07863 DB00579] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0010033| response to organic substance PPARG;SLC6A4 GO:0007584| response to nutrient SLC6A4;PPARG GO:0014070| response to organic cyclic compound SLC6A3;PPARG GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0042493| response to drug SLC6A2;PPARG;SLC6A4;SLC6A3 7581:[DB07863 DB04895] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04895|Pegaptanib NRP1 common genes common pathways GO:0007507| heart development PPARG;NRP1;RXRA GO:0007165| signal transduction PPARG;NRP1 7582:[DB07863 DB00678] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;ABCB11;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway AGTR1;PPARG GO:0007165| signal transduction AGTR1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0042493| response to drug PPARG;UGT1A1;SLC22A12;ABCB1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process UGT2B7;PPARG;CYP2C9;CYP3A4 7583:[DB07863 DB14538] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP11B2;CYP11B1 GO:0045087| innate immune response ANXA1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;RXRA GO:0043065| positive regulation of apoptotic process PPARG;ANXA1 GO:0006351| transcription, DNA-dependent NCOA2;NR3C1;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA GO:0042493| response to drug PPARG;ABCB1;HSD11B2;ABCG2;ANXA1 GO:0007165| signal transduction NR3C1;PPARG;ANXA1 GO:0032870| cellular response to hormone stimulus CYP11B1;NCOA2;CYP11B2 GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0007186| G-protein coupled receptor signaling pathway ANXA1;PPARG GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0015721| bile acid and bile salt transport RXRA;SLCO1A2;NCOA2 GO:0014070| response to organic cyclic compound ANXA1;PPARG 7584:[DB07863 DB01384] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0006351| transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;NR3C1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR3C1 7585:[DB07863 DB06712] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 GO:0007507| heart development CACNA1C;RXRA;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043010| camera-type eye development RXRA;CACNA1C 7586:[DB07863 DB00401] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007507| heart development CACNA1C;RXRA;PPARG GO:0042493| response to drug ABCB1;PPARG GO:0043010| camera-type eye development CACNA1C;RXRA 7587:[DB07863 DB01054] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways GO:0043010| camera-type eye development RXRA;CACNA1C GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 GO:0007507| heart development CACNA1C;RXRA;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug ABCB1;PPARG 7588:[DB07863 DB01274] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0009409| response to cold ADRB2;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2 GO:0007165| signal transduction ADRB2;PPARG 7589:[DB07863 DB00669] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug PPARG;ABCB1;HTR1B;ABCG2 GO:0015721| bile acid and bile salt transport RXRA;SLCO1B1;NCOA2;SLCO1A2 GO:0007165| signal transduction HTR1F;HTR1B;HTR1A;PPARG;HTR1D GO:0007186| G-protein coupled receptor signaling pathway HTR1D;HTR1A;PPARG;HTR1B;HTR1F 7590:[DB07863 DB01151] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0007584| response to nutrient SLC6A4;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG;SLC6A4 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0007165| signal transduction CHRM3;HRH1;SMPD1;ADRA1D;CHRM5;CHRM2;HTR2A;ADRB2;ADRA2B;ADRA2C;CHRM1;HTR1A;PPARG;CHRM4;ADRB1;ADRA1A;DRD2;ADRA2A;HTR2C;ADRA1B GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway ADRB1;ADRA1A;DRD2;CHRM4;HTR2C;ADRA1B;ADRA2A;ADRA1D;CHRM5;HRH1;CHRM3;HTR1A;PPARG;ADRA2C;CHRM1;HTR2A;ADRB2;ADRA2B;CHRM2 GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug HTR2A;CYP2E1;PPARG;SMPD1;SLC6A2;CYP1A2;HTR2C;SLC6A4;ABCB1;ADRA1A;DRD2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;ADRB2;NCOA2 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0009409| response to cold PPARG;ADRB2;ADRB1 GO:0007623| circadian rhythm NCOA2;SLC6A4 7591:[DB07863 DB06636] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCB1 7592:[DB07863 DB00081] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction PPARG;FCGR2B;FCGR2C;FCGR1A GO:0016032| viral reproduction RXRA;FCGR2B GO:0045087| innate immune response C1R;C1QB;C1QC;PPARG;C1QA;FCGR1A 7593:[DB07863 DB00490] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway DRD2;PPARG;HTR1A GO:0007165| signal transduction DRD2;PPARG;HTR1A GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCB1;DRD2 GO:0032922| circadian regulation of gene expression NCOA2;DRD2 7594:[DB07863 DB01043] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway DRD2;PPARG GO:0007165| signal transduction PPARG;HTR3A;DRD2;CHRNA7 GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;GRIN1;NCOA2;PPARG;RXRA GO:0043065| positive regulation of apoptotic process GRIN2A;PPARG;GRIN1 GO:0042493| response to drug PPARG;DRD2;GRIN2A GO:0032922| circadian regulation of gene expression NCOA2;DRD2 7595:[DB07863 DB00968] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0042493| response to drug COMT;PPARG GO:0007623| circadian rhythm NCOA2;DDC GO:0014070| response to organic cyclic compound PPARG;COMT GO:0043627| response to estrogen stimulus COMT;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;PPARG GO:0007165| signal transduction PPARG;ADRA2A GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis ADRA2A;PPARG 7596:[DB07863 DB01107] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRB3;GABRE;GABRQ;GABRA5;GABRB1;GABRD;GABRA6;PPARG;GABRP GO:0042493| response to drug PPARG;GABRG3 7597:[DB07863 DB01076] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;AHR;PPARG GO:0010033| response to organic substance ABCC4;PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;HMGCR;PPARG GO:0048511| rhythmic process NCOA2;AHR;PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0015721| bile acid and bile salt transport NCOA2;SLCO1A2;SLCO1B3;ABCB11;RXRA;SLCO1B1;SLCO2B1 GO:0014070| response to organic cyclic compound ABCC4;UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;ABCC2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0019216| regulation of lipid metabolic process PPARG;RXRA;HMGCR;NCOA2 GO:0032922| circadian regulation of gene expression AHR;NCOA2 GO:0030522| intracellular receptor mediated signaling pathway AHR;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;AHR GO:0006355| regulation of transcription, DNA-dependent AHR;NCOA2;PPARG;RXRA GO:0042493| response to drug ABCC2;ABCC4;ABCB1;PPARG;ABCC1;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;UGT2B7;PPARG;CYP2C9;CYP3A4;HMGCR GO:0042594| response to starvation UGT1A1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;AHR GO:0006351| transcription, DNA-dependent NCOA2;AHR;PPARG;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AHR GO:0008203| cholesterol metabolic process HMGCR;RXRA 7598:[DB07863 DB09073] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter CDK4;PPARG;RXRA GO:0007623| circadian rhythm CDK4;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process CDK4;PPARG GO:0008285| negative regulation of cell proliferation CDK6;PPARG GO:0010033| response to organic substance CDK4;PPARG GO:0032869| cellular response to insulin stimulus CDK4;PPARG GO:0007165| signal transduction CDK4;PPARG;CDK6 GO:0031100| organ regeneration PPARG;CDK4 7599:[DB07863 DB08816] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9;CYP2D6 GO:0007165| signal transduction P2RY12;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;P2RY12 7600:[DB07863 DB01418] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01418|Acenocoumarol VKORC1;CYP2C9;CYP1A2;CYP2C19;CYP3A4;ALB;ORM1 common genes common pathways GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4;CYP1A2 GO:0042493| response to drug PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB 7601:[DB07863 DB00356] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug CYP1A2;PPARG;CYP1A1;CYP2E1 GO:0043065| positive regulation of apoptotic process PPARG;KCNMA1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2;CYP2D6 GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 7602:[DB07863 DB09039] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;UGCG;CYP3A4;PPARG 7603:[DB07863 DB01332] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways 7604:[DB07863 DB06016] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0042493| response to drug DRD3;HTR2A;PPARG;DRD2;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD3;DRD2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0007507| heart development HTR2B;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0007165| signal transduction DRD2;HTR2B;HRH1;DRD3;HTR2A;HTR1A;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;DRD3;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2B;DRD2;HTR1A;PPARG;HTR2A;DRD3;HRH1 7605:[DB07863 DB00322] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;TYMS GO:0042493| response to drug PPARG;TYMS GO:0033189| response to vitamin A TYMS;PPARG GO:0007623| circadian rhythm NCOA2;TYMS GO:0006629| lipid metabolic process PPARG;CYP2C9 7606:[DB07863 DB01216] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;SRD5A1 GO:0014070| response to organic cyclic compound SRD5A2;PPARG;SRD5A1 GO:0010033| response to organic substance SRD5A2;PPARG GO:0043627| response to estrogen stimulus SRD5A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;SRD5A2;AKR1D1;SRD5A1 GO:0042493| response to drug SRD5A1;SRD5A2;PPARG 7607:[DB07863 DB00371] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0007165| signal transduction GABRD;GABRA6;PPARG;GABRP;GABRE;GABRQ;GABRB1;GABRA5;GABRB3 GO:0042493| response to drug CYP2E1;PPARG;GABRG3 7608:[DB07863 DB06684] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance SLC6A4;PPARG GO:0007165| signal transduction HTR1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;HTR1A GO:0042493| response to drug PPARG;SLC6A4 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2 7609:[DB07863 DB00530] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0033993| response to lipid EGFR;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction PPARG;NR1I2;EGFR GO:0014070| response to organic cyclic compound EGFR;UGT1A1;CYP1A2;PPARG;CYP1A1 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;NCOA2;RXRA GO:0007584| response to nutrient UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG GO:0010033| response to organic substance UGT1A1;CYP1A2;PPARG;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;EGFR GO:0007623| circadian rhythm EGFR;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1I2;PPARG GO:0006351| transcription, DNA-dependent PPARG;NR1I2;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;RXRA;NR1I2;PPARG;NCOA2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2D6 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;PPARG;CYP1A2;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR1I2;RXRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;NR1I2;PPARG;EGFR GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG GO:0033189| response to vitamin A CYP1A1;PPARG 7610:[DB07863 DB00903] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:1904706| PPARG;GSTP1 GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;LEF1 GO:0042493| response to drug ATP1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent LEF1;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;LEF1;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;LEF1;RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;LEF1 GO:0006351| transcription, DNA-dependent PPARG;RXRA;LEF1;NCOA2 GO:0043401| steroid hormone mediated signaling pathway LEF1;PPARG;RXRA GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0045892| negative regulation of transcription, DNA-dependent LEF1;NCOA2;PPARG GO:0008217| regulation of blood pressure ATP1A1;PPARG GO:0030855| epithelial cell differentiation GSTA2;PPARG GO:0031100| organ regeneration GSTP1;PPARG GO:0032869| cellular response to insulin stimulus GSTP1;PPARG 7611:[DB07863 DB01223] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;HDAC2 GO:0071300| cellular response to retinoic acid PPARG;HDAC2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;HDAC2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2;PDE3A GO:0006351| transcription, DNA-dependent HDAC2;NCOA2;RXRA;PPARG GO:0032922| circadian regulation of gene expression NCOA2;HDAC2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;HDAC2 GO:0042493| response to drug HDAC2;CYP1A2;PDE3A;CYP2E1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;HDAC2 GO:0007165| signal transduction PDE3A;ADORA3;PPARG;ADORA1 GO:0007186| G-protein coupled receptor signaling pathway PDE3A;ADORA3;PPARG;ADORA1 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;PPARG GO:0048511| rhythmic process PPARG;NCOA2;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;HDAC2 GO:0031000| response to caffeine HDAC2;PPARG GO:0008285| negative regulation of cell proliferation ADORA3;ADORA1;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG 7612:[DB07863 DB00108] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0016032| viral reproduction ICAM1;FCGR2B;RXRA GO:0042493| response to drug PPARG;ICAM1 GO:0045087| innate immune response PPARG;C1QC;C1QB;C1R;FCGR1A;C1QA GO:0014070| response to organic cyclic compound PPARG;ICAM1 GO:0007165| signal transduction FCGR2B;PPARG;FCGR2C;FCGR1A 7613:[DB07863 DB09236] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways GO:0043010| camera-type eye development RXRA;CACNA1C GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0007507| heart development CACNA1C;RXRA;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 7614:[DB07863 DB08930] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes common pathways GO:0042493| response to drug PPARG;UGT1A1;ABCG2;ABCB1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance PPARG;UGT1A1 GO:0019216| regulation of lipid metabolic process PPARG;RXRA;UGT1A9;NCOA2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 7615:[DB07863 DB04905] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0042493| response to drug CYP1A1;PPARG;ABCB1 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway HRH1;PPARG GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction HRH1;PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1 7616:[DB07863 DB00682] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00682|Warfarin VKORC1;NR1I2;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2C8;CYP2C18;CYP1A1;ALB;ORM1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0042493| response to drug PPARG;CYP1A1;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent RXRA;NR1I2;PPARG;NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;CYP1A1 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0010033| response to organic substance CYP1A1;PPARG;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007165| signal transduction PPARG;NR1I2 7617:[DB07863 DB11397] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0042493| response to drug PPARG;BCHE GO:0007584| response to nutrient PPARG;BCHE GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB 7618:[DB07863 DB01589] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 GO:0042493| response to drug PPARG;GABRG3 GO:0007165| signal transduction GABRD;PPARG;GABRA6;GABRP;GABRE;GABRR2;GABRQ;GABRB1;GABRA5;GABRB3 7619:[DB07863 DB00104] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation SSTR2;PPARG;SSTR1 GO:0009612| response to mechanical stimulus MPO;PPARG GO:0008285| negative regulation of cell proliferation SSTR5;SSTR2;SSTR1;PPARG GO:0007584| response to nutrient SSTR2;SSTR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway SSTR2;PPARG;SSTR1;SSTR5 GO:0007165| signal transduction SSTR2;SSTR1;PPARG;SSTR5 GO:0042593| glucose homeostasis SSTR5;PPARG 7620:[DB07863 DB06414] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06414|Etravirine CYP3A4;CYP2C9;CYP2C19;ABCB1;ABCB4 common genes common pathways GO:0019216| regulation of lipid metabolic process ABCB4;NCOA2;PPARG;RXRA GO:0014070| response to organic cyclic compound ABCB4;PPARG GO:0055088| lipid homeostasis PPARG;ABCB4 GO:0001890| placenta development ABCB4;RXRA;PPARG GO:0010033| response to organic substance ABCB4;PPARG GO:0007623| circadian rhythm ABCB4;NCOA2 GO:0006629| lipid metabolic process ABCB4;CYP3A4;PPARG;CYP2C9 GO:0042493| response to drug ABCB1;ABCB4;PPARG GO:0033189| response to vitamin A ABCB4;PPARG 7621:[DB07863 DB00633] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042493| response to drug PPARG;CYP1A1;CYP2E1;CYP1A2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;PPARG GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0007165| signal transduction ADRA2A;PPARG GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG 7622:[DB07863 DB01587] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0007165| signal transduction GABRE;GABRB1;TSPO;GABRD;PPARG GO:0042493| response to drug ABCB1;PPARG;TSPO GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;TSPO 7623:[DB07863 DB09154] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 7624:[DB07863 DB01583] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLC10A1;RXRA;SLCO1B1;SLCO1B3;NCOA2;SLCO1C1;SLCO1A2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;THRA;PPARG;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;PPARG;RXRA;THRA;NCOA2 GO:0009409| response to cold PPARG;THRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;THRB GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter THRA;RXRA;PPARG;THRB GO:0006351| transcription, DNA-dependent THRB;RXRA;PPARG;NCOA2;THRA GO:0043401| steroid hormone mediated signaling pathway THRB;RXRA;PPARG;THRA GO:0030522| intracellular receptor mediated signaling pathway THRA;NCOA2;THRB GO:0016032| viral reproduction SLC10A1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;THRA;THRB GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;THRA;THRB GO:0042493| response to drug PPARG;ABCB1 7625:[DB07863 DB00331] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0007165| signal transduction PRKAB1;PPARG GO:0006629| lipid metabolic process PPARG;PRKAB1 7626:[DB07863 DB09230] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 7627:[DB07863 DB01264] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01264|Darunavir pol;CYP3A4;SLCO1B1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug ABCB1;PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;NCOA2 7628:[DB07863 DB00850] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway DRD2;DRD1;CALM1;PPARG GO:0007165| signal transduction PPARG;DRD1;DRD2 GO:0042493| response to drug PPARG;CYP1A2;DRD1;DRD2 GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;DRD2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2C9;CYP3A4;CYP2D6 7629:[DB07863 DB05514] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05514|Cobiprostone CLCN2 common genes common pathways 7630:[DB07863 DB01559] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRB3;GABRA5;GABRB1;GABRE;GABRR2;GABRP;PPARG;GABRD GO:0042493| response to drug PPARG;GABRG3 GO:0006629| lipid metabolic process CYP3A4;PPARG 7631:[DB07863 DB04794] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug CYP2E1;PPARG 7632:[DB07863 DB12141] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0048469| cell maturation AXL;PPARG GO:0007623| circadian rhythm NCOA2;HTR7 GO:0007507| heart development PPARG;RXRA;HTR2B GO:0045087| innate immune response PPARG;AXL GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug HTR2B;HTR2C;ABCG2;HTR1B;ABCB1;PPARG;HTR2A GO:0016032| viral reproduction RXRA;HTR2A;AXL GO:0007186| G-protein coupled receptor signaling pathway HTR7;HTR1B;HTR1E;HTR1F;HTR6;HTR2B;HTR2C;HTR1D;HTR4;HTR2A;PPARG;HTR1A GO:0007165| signal transduction HTR7;HTR3B;HTR3A;HTR3D;HTR1B;HTR1E;HTR1F;HTR6;HTR2B;HTR2C;HTR1D;ALK;AXL;HTR3E;HTR4;HTR2A;HTR1A;HTR3C;PPARG GO:0031100| organ regeneration FLT3;PPARG;AXL GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;HTR2C GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB 7633:[DB07863 DB00252] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport ALB;SLCO1C1;NCOA2;RXRA GO:0019216| regulation of lipid metabolic process UGT1A9;NCOA2;PPARG;RXRA GO:0007165| signal transduction NR1I2;PPARG GO:0032870| cellular response to hormone stimulus CYP11B1;NCOA2;UGT1A1;ABCC2 GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0042493| response to drug UGT1A1;PPARG;ABCB1;ABCC2 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;NR1I2;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;NR1I2;RXRA;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;CYP3A4;CYP11B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NR1I2;NCOA2 7634:[DB07863 DB00078] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0045087| innate immune response C1QB;C1R;C1QC;PPARG;C1S;C1QA;FCGR1A GO:0016032| viral reproduction RXRA;FCGR2B GO:0007165| signal transduction FCGR2B;PPARG;FCGR2C;FCGR1A 7635:[DB07863 DB04946] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG GO:0007623| circadian rhythm NCOA2;HTR7 GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0016032| viral reproduction HTR2A;RXRA GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0042493| response to drug CYP2E1;PPARG;HTR2A;DRD3;DRD1;DRD2;ADRA1A GO:0007165| signal transduction HTR2A;DRD3;HTR1A;PPARG;DRD4;ADRA2C;HRH1;DRD1;HTR6;HTR7;ADRA1A;DRD2 GO:0007186| G-protein coupled receptor signaling pathway DRD1;HTR6;HTR7;ADRA1A;DRD2;HTR2A;DRD3;HTR1A;PPARG;DRD4;ADRA2C;HRH1 GO:0019216| regulation of lipid metabolic process NCOA2;DRD3;RXRA;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0048511| rhythmic process NCOA2;PPARG;DRD4 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 7636:[DB07863 DB14064] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCB1 7637:[DB07863 DB06814] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06814|Protokylol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;ADRB2;RXRA GO:0009409| response to cold ADRB2;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG GO:0007165| signal transduction ADRB2;PPARG 7638:[DB07863 DB00773] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;ABCC2;CYP1A2;UGT1A1;PTGS2;ABCC6;ABCC1;PPARG;CYP2E1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:1904706| GSTP1;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP1A2;CYP3A4;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0043065| positive regulation of apoptotic process TOP2A;PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;RXRA;NCOA2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1;CYP1A2;PTGS2 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0048511| rhythmic process PPARG;TOP2A;NCOA2 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance UGT1A1;CYP1A2;PTGS2;PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ABCC3 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0032869| cellular response to insulin stimulus GSTP1;PPARG GO:0007566| embryo implantation PTGS2;RXRA GO:0031100| organ regeneration UGT1A1;PPARG;GSTP1 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2;UGT1A1 7639:[DB07863 DB00580] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0042493| response to drug PTGS2;PPARG GO:0007566| embryo implantation RXRA;PTGS2 GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG;CA2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0043627| response to estrogen stimulus CA2;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 7640:[DB07863 DB00515] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PPARG;CYP2C9 GO:0043065| positive regulation of apoptotic process PPARG;SOD1;PTGS2 GO:0009612| response to mechanical stimulus MPO;PPARG GO:0042493| response to drug PPARG;SOD1;BCHE;PTGS2;ABCC6;ABCG2;ABCC2;ABCB1 GO:0001701| in utero embryonic development RXRA;ATP7A GO:1904706| GSTP1;PPARG GO:0032869| cellular response to insulin stimulus GSTP1;PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;CYP4A11 GO:0007566| embryo implantation RXRA;SOD1;PTGS2 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0014070| response to organic cyclic compound PTGS2;NQO1;PPARG GO:0006919| activation of caspase activity PPARG;XDH GO:0007584| response to nutrient NQO1;PPARG;BCHE GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0008217| regulation of blood pressure SOD1;PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;SOD1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2;BCHE GO:0015721| bile acid and bile salt transport NCOA2;ABCC3;RXRA;ALB GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0001890| placenta development PPARG;RXRA;SOD1 7641:[DB07863 DB00794] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0007165| signal transduction GABRP;PPARG;GABRA6;GABRD;GABRB1;GABRA5;GABRQ;GABRE;CHRNA7;GABRB3;CHRNA4;GRIA2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance PPARG;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2;PPARG;GABRG3 7642:[DB07863 DB00178] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure ACE;PPARG GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0007584| response to nutrient PPARG;BCHE GO:0007165| signal transduction PPARG;BDKRB1 GO:0007186| G-protein coupled receptor signaling pathway BDKRB1;PPARG GO:0042493| response to drug PPARG;BCHE GO:0009612| response to mechanical stimulus BDKRB1;PPARG GO:0030308| negative regulation of cell growth BDKRB1;PPARG 7643:[DB07863 DB09227] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development PPARG;RXRA;CACNA1C GO:0043010| camera-type eye development CACNA1C;RXRA 7644:[DB07863 DB00925] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;CALM1;ADRA2A;ADRA1B;ADRA1D;ADRA2B;ADRB2;ADRA2C;PPARG GO:0007165| signal transduction ADRA1A;ADRA2A;ADRA1B;ADRA1D;ADRB2;ADRA2B;ADRA2C;PPARG GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0042493| response to drug ADRA1A;PPARG GO:0009409| response to cold PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ADRB2;RXRA;PPARG 7645:[DB07863 DB12418] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12418|Saccharin CA3 common genes common pathways 7646:[DB07863 DB09167] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP1A2;CYP2D6 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0042493| response to drug ADRA1A;SLC6A4;SLC6A2;CYP1A2;HTR2A;PPARG GO:0007165| signal transduction CHRM4;ADRA1A;ADRA2A;ADRA1B;HRH1;CHRM3;CHRM5;ADRA1D;CHRM2;ADRA2B;HTR2A;CHRM1;ADRA2C;PPARG;HTR1A GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;ADRA2A;ADRA1A;CHRM4;HTR1A;PPARG;ADRA2C;CHRM1;HTR2A;ADRA2B;CHRM2;ADRA1D;CHRM5;HRH1;CHRM3 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance SLC6A4;PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0014070| response to organic cyclic compound CYP1A2;PPARG 7647:[DB07863 DB00446] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways GO:0016032| viral reproduction RXRA;CD55 GO:0045087| innate immune response CD55;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7648:[DB07863 DB01973] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 7649:[DB07863 DB00373] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0007165| signal transduction ADRB1;PPARG;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ADRB2;NCOA2 GO:0009409| response to cold ADRB2;PPARG;ADRB1 GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0042493| response to drug ABCB1;PPARG 7650:[DB07863 DB00393] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C2 GO:0032922| circadian regulation of gene expression NCOA2;AHR GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AHR GO:0045893| positive regulation of transcription, DNA-dependent AHR;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NR3C2;NCOA2;AHR;RXRA;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007507| heart development CACNA1C;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;AHR;NCOA2 GO:0006351| transcription, DNA-dependent AHR;NCOA2;PPARG;RXRA;NR3C2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR3C2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;AHR GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;AHR;PPARG GO:0048511| rhythmic process PPARG;NCOA2;AHR GO:0007165| signal transduction NR3C2;PPARG GO:0043010| camera-type eye development RXRA;CACNA1C 7651:[DB07863 DB00825] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0010033| response to organic substance TRPA1;PPARG GO:0014070| response to organic cyclic compound PPARG;TRPA1 GO:0007165| signal transduction PPARG;OPRK1 GO:0043010| camera-type eye development RXRA;CACNA1C GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG GO:0051289| protein homotetramerization TRPM8;RXRA;TRPA1 GO:0042493| response to drug PPARG;TRPA1 GO:0007507| heart development RXRA;PPARG;CACNA1C GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0009409| response to cold TRPM8;PPARG;TRPA1 7652:[DB07863 DB01105] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0042493| response to drug SLC6A3;SLC6A4;SLC6A2;PPARG GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance PPARG;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;PPARG 7653:[DB07863 DB00207] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;PADI4;RXRA GO:0042493| response to drug ABCB1;PPARG GO:0045087| innate immune response PPARG;PADI4 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006351| transcription, DNA-dependent RXRA;PADI4;PPARG;NCOA2 7654:[DB07863 DB06290] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes common pathways GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2 GO:0016032| viral reproduction SLC10A1;RXRA GO:0042493| response to drug PPARG;CYP1A2;ABCG2;ABCC2;ABCB1 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLC10A1;SLCO1B1;RXRA;ABCB11;SLCO1B3;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 7655:[DB07863 DB06287] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0007584| response to nutrient MTOR;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;MTOR GO:0007165| signal transduction MTOR;PPARG 7656:[DB07863 DB11995] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug PPARG;ABCB1;ABCG2 GO:0006629| lipid metabolic process CYP2C9;PPARG 7657:[DB07863 DB06457] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06457|Tecastemizole KCNH2 common genes common pathways 7658:[DB07863 DB00829] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00829|Diazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9;CYP2B6;CYP2C18;CYP2C8;PTGS1;CYP2E1;ALB;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;PPARG;CYP2C9;CYP3A4 GO:0043065| positive regulation of apoptotic process TSPO;PPARG GO:0042493| response to drug CYP2E1;PPARG;TSPO;ABCB1;GABRG3 GO:0007165| signal transduction GABRB3;GABRD;TSPO;GABRA6;PPARG;GABRP;GABRE;GABRR2;GABRQ;GABRB1;GABRA5 GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB 7659:[DB07863 DB00864] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00864|Tacrolimus FKBP1A;CYP3A7;CYP3A5;CYP3A4;ALB;ORM1;ABCB1;ABCA5;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0055010| ventricular cardiac muscle tissue morphogenesis FKBP1A;RXRA GO:0031000| response to caffeine PPARG;FKBP1A GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;NCOA2;ALB GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ABCA5 7660:[DB07863 DB00734] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0007623| circadian rhythm NCOA2;HTR7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;DRD3;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2;DRD2 GO:0042493| response to drug HTR2A;DRD3;PPARG;DRD2;ADRA1A;DRD1;HTR2C GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0016032| viral reproduction RXRA;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HRH1;HTR1D;HTR2A;ADRA2B;DRD3;HTR1A;PPARG;DRD4;ADRA2C;HTR7;DRD2;ADRA1A;DRD1;HTR2C;ADRA1B;ADRA2A GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;DRD3;RXRA GO:0007165| signal transduction HTR1A;DRD4;PPARG;ADRA2C;HTR2A;ADRA2B;DRD3;HTR1D;HRH1;HTR2C;ADRA1B;ADRA2A;DRD1;ADRA1A;DRD2;HTR7 GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0048511| rhythmic process NCOA2;PPARG;DRD4 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;HTR2C 7661:[DB07863 DB00653] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways GO:0007507| heart development PPARG;RXRA;CACNA1C GO:0043010| camera-type eye development RXRA;CACNA1C 7662:[DB07863 DB00573] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes PPARG common pathways GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0045600| positive regulation of fat cell differentiation PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development RXRA;PPARG GO:0019395| fatty acid oxidation PPARG GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process NCOA2;PPARA;PPARG GO:0007584| response to nutrient PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance PPARG;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0019216| regulation of lipid metabolic process PPARG;PPARA;RXRA;NCOA2 GO:0007566| embryo implantation RXRA;PTGS2 GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0007165| signal transduction PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0042493| response to drug PPARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARA;PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0030224| monocyte differentiation PPARG GO:0061614| PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;PPARA GO:0032922| circadian regulation of gene expression PPARA;NCOA2 GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;PPARA GO:0050872| white fat cell differentiation PPARG GO:0033189| response to vitamin A PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:1904706| PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0030308| negative regulation of cell growth PPARG GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;PPARA GO:0006351| transcription, DNA-dependent PPARG;PPARA;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;PPARA;NCOA2 GO:0071300| cellular response to retinoic acid PPARG GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0007507| heart development RXRA;PPARA;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;RXRA;NCOA2 GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process PTGS1;PTGS2;PPARG;PPARA GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG 7663:[DB07863 DB00788] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0007566| embryo implantation RXRA;PTGS2 GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2;SLCO1A2;ALB GO:0007584| response to nutrient UGT1A1;PPARG GO:0008217| regulation of blood pressure PTGS1;PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2;CYP1A2;UGT1A1 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2;UGT1A1;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PTGS1;UGT2B7;CYP2C9;PPARG;CYP1A2;PTGS2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1;CYP1A2;PPARG 7664:[DB07863 DB01267] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01267|Paliperidone HTR2A;DRD2;HRH1;ADRA1A;ADRA1B;DRD4;HTR1D;DRD3;HTR2C;ADRA2A;ADRA2B;ADRA2C;HTR1A;DRD1;HTR7;CYP3A4;CYP2D6;CYP3A5;ABCB1 common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis PPARG;ADRA2A;ADRA1B GO:0007165| signal transduction HTR1D;HRH1;HTR2A;ADRA2B;DRD3;HTR1A;DRD4;PPARG;ADRA2C;HTR7;ADRA1A;DRD2;DRD1;HTR2C;ADRA1B;ADRA2A GO:0019216| regulation of lipid metabolic process DRD3;RXRA;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway DRD2;ADRA1A;HTR7;ADRA2A;HTR2C;ADRA1B;DRD1;HRH1;HTR1D;ADRA2C;HTR1A;PPARG;DRD4;DRD3;HTR2A;ADRA2B GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;HTR2C GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;PPARG GO:0048511| rhythmic process DRD4;PPARG;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;DRD3;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;DRD3;RXRA GO:0007623| circadian rhythm HTR7;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0042493| response to drug PPARG;DRD3;HTR2A;DRD2;ADRA1A;ABCB1;HTR2C;DRD1 7665:[DB07863 DB00224] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00224|Indinavir pol;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;ABCB1;SLC22A1;ABCC1;SLCO1A2;SLCO1B1;ABCC2;SLCO2B1;ABCB11 common genes common pathways GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2;UGT1A1 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;SLCO1B1;RXRA;ABCB11;SLCO2B1 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance PPARG;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug ABCC2;ABCB1;PPARG;ABCC1;UGT1A1 7666:[DB07863 DB00869] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010033| response to organic substance PPARG;CA2 7667:[DB07863 DB00539] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;ESR1;PPARG GO:0006351| transcription, DNA-dependent NCOA2;ESR1;PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1;NCOA2 GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;ESR1;PPARG;NCOA2 GO:0042493| response to drug ABCB1;PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1;RXRA GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction PPARG;ESR1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0010033| response to organic substance PPARG;CYP1A1 7668:[DB07863 DB09061] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes PPARG common pathways GO:0061614| PPARG GO:0030224| monocyte differentiation PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2 GO:0042493| response to drug CAT;ABCG2;TRPA1;SOD1;HTR2A;CYP1A1;PPARG;ABCC1;SMPD1;PTGS2;CYP1A2 GO:1904706| PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0050872| white fat cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA GO:0042752| regulation of circadian rhythm PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0016032| viral reproduction VDAC1;HTR2A;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0051289| protein homotetramerization TRPV1;CAT;TRPM8;CRYZ;TRPA1;RXRA GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0048469| cell maturation PPARG GO:0030308| negative regulation of cell growth PPARG GO:0008203| cholesterol metabolic process RXRA;HMGCR;CAT GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0007623| circadian rhythm AANAT;NCOA2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;CYP2C9;PPARG;HMGCR;PTGS2;CYP1A2 GO:0045165| cell fate commitment PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;TRPV4;TRPV1 GO:0007507| heart development RXRA;PPARG GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;PLA2G1B GO:0043065| positive regulation of apoptotic process PTGS2;SMPD1;PPARG;CNR1;SOD1;TRPV1;CYP1B1;IDO1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1;ACAT1;AANAT GO:0006919| activation of caspase activity PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0008217| regulation of blood pressure SOD1;PPARG;PTGS2;PTGS1 GO:0031000| response to caffeine PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PTGS2;OPRM1;ADORA1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process NCOA2;PPARG;AANAT GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;RXRA;PPARG GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0007566| embryo implantation SOD1;RXRA;PTGS2 GO:0019216| regulation of lipid metabolic process HMGCR;NCOA2;PPARG;CYP1A1;CNR1;RXRA GO:0007186| G-protein coupled receptor signaling pathway GPR18;HTR2A;CNR1;GPR12;HTR1A;GPR55;PPARG;ADORA1;OPRD1;OPRM1;CNR2 GO:1905461| PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;HTR3A;CHRNA7;CNR2;OPRM1;SMPD1;OPRD1;ADORA1;PPARG;GPR55;HTR1A;HTR2A;GPR18;CNR1;GPR12 GO:0033993| response to lipid PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0010891| negative regulation of sequestering of triglyceride PPARG 7669:[DB07863 DB00397] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;DRD1;ADRB1;PPARG;ADRA2C;ADRB2;ADRA2B GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0007165| signal transduction DRD1;ADRA2A;ADRB1;ADRA2B;ADRB2;ADRA2C;PPARG GO:0009409| response to cold ADRB1;PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RXRA;PPARG;NCOA2 GO:0042493| response to drug PPARG;DRD1 7670:[DB07863 DB00908] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00908|Quinidine SCN5A;KCNK1;KCNK6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A7;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP2B6;CYP2C9;CYP2C8;ORM1;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A8;ABCC2;SLC22A4;SLCO1B1;ABCB11 common genes common pathways GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRA1B;ADRA1D;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0007165| signal transduction PPARG;ADRA1D;ADRA1B;ADRA1A GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;RXRA;SLCO1A2;NCOA2 GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0010033| response to organic substance PPARG;CYP1A1;CYP1A2 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2C9;CYP3A4;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042493| response to drug CYP1A2;CYP2E1;PPARG;CYP1A1;ABCB1;ADRA1A;ABCC2 GO:0033189| response to vitamin A PPARG;CYP1A1 7671:[DB07863 DB05012] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05012|XEN2174 SLC6A2 common genes common pathways GO:0042493| response to drug PPARG;SLC6A2 7672:[DB07863 DB00728] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0007165| signal transduction HTR3A;CHRNA2;PPARG;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway CHRM2;PPARG GO:0015721| bile acid and bile salt transport NCOA2;SLCO1A2;RXRA 7673:[DB07863 DB00612] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PPARG GO:0009409| response to cold ADRB2;PPARG;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2;ADRB1 GO:0007165| signal transduction ADRB2;PPARG;ADRB1 7674:[DB07863 DB00213] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;SLCO1B1;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCG2;ABCB1 7675:[DB07863 DB08922] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0048511| rhythmic process PPARG;DRD4;NCOA2 GO:0010033| response to organic substance PPARG;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;DRD2;ADRA1A GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0007186| G-protein coupled receptor signaling pathway HRH1;ADRA1D;HTR2A;HTR1A;DRD4;PPARG;DRD2;ADRA1A;ADRA1B GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0007165| signal transduction HTR2A;PPARG;DRD4;HTR1A;HRH1;ADRA1D;ADRA1B;ADRA1A;DRD2 GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0042493| response to drug ADRA1A;DRD2;HTR2A;PPARG;CYP1A1 GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0033189| response to vitamin A CYP1A1;PPARG GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0016032| viral reproduction HTR2A;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;NCOA2 7676:[DB07863 DB01576] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0042493| response to drug SLC6A2;PPARG;ADRA1A;SLC6A3 GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0007165| signal transduction ADRA1A;ADRA1B;TAAR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRA1B;TAAR1;PPARG 7677:[DB07863 DB01068] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;NCOA2 GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0007165| signal transduction GABRB3;GABRP;NR1I2;GABRD;TSPO;GABRA6;PPARG;GABRQ;GABRB1;GABRA5;GABRE GO:0042493| response to drug GABRG3;TSPO;CYP2E1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1I2 GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1I2;PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;NR1I2;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process TSPO;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NR1I2;NCOA2 7678:[DB07863 DB03615] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB03615|Ribostamycin P4HB;rpsL common genes common pathways 7679:[DB07863 DB11598] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11598|Antithrombin III human SERPINC1 common genes common pathways GO:0007584| response to nutrient PPARG;SERPINC1 7680:[DB07863 DB00270] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways GO:0007507| heart development CACNA1C;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043010| camera-type eye development RXRA;CACNA1C GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2 7681:[DB07863 DB00999] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010033| response to organic substance PPARG;CA2 GO:0043065| positive regulation of apoptotic process KCNMA1;PPARG 7682:[DB07863 DB00741] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0007165| signal transduction ANXA1;PPARG;NR3C1 GO:0032870| cellular response to hormone stimulus NCOA2;CYP11B1;CYP11B2 GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0007186| G-protein coupled receptor signaling pathway ANXA1;PPARG GO:0008217| regulation of blood pressure PPARG;CYP11B1 GO:0015721| bile acid and bile salt transport NCOA2;SLCO1A2;RXRA GO:0014070| response to organic cyclic compound PPARG;ANXA1 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;PPARG;CYP3A4 GO:0045087| innate immune response PPARG;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0043065| positive regulation of apoptotic process ANXA1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0006351| transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG;RXRA GO:0042493| response to drug PPARG;ABCB1;ANXA1;ABCG2;HSD11B2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR3C1;RXRA;PPARG 7683:[DB07863 DB08872] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways 7684:[DB07863 DB00233] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CHUK;PPARG;RXRA GO:0042493| response to drug PPARG;PTGS2;CHUK GO:0009612| response to mechanical stimulus MPO;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;CHUK GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG;PLA2G2E GO:0045087| innate immune response PPARG;CHUK GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance CHUK;PTGS2;PPARG GO:0007566| embryo implantation RXRA;PTGS2 7685:[DB07863 DB05155] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05155|CR665 OPRK1 common genes common pathways GO:0007165| signal transduction OPRK1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG 7686:[DB07863 DB09080] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0007165| signal transduction ADRB2;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG GO:0009409| response to cold ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;ADRB2 GO:0006629| lipid metabolic process PPARG;CYP2C9 7687:[DB07863 DB06654] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug CYP1A2;MAOB;PPARG;CYP1A1;CYP2E1;ABCG2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;PPARG;CYP2C9;CYP3A4 GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CYP1A1;RXRA 7688:[DB07863 DB00613] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9 GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug PPARG;CYP1A1;ABCB1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG GO:0010033| response to organic substance CYP1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1 7689:[DB07863 DB14518] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0008217| regulation of blood pressure PPARG;ATP1A1 GO:0008285| negative regulation of cell proliferation PPARG;APP GO:0007186| G-protein coupled receptor signaling pathway PPARG;APP GO:0042493| response to drug ATP1A1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0008203| cholesterol metabolic process RXRA;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;APP GO:0043065| positive regulation of apoptotic process APP;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;NCOA2;RXRA;PPARG GO:0045087| innate immune response APP;PPARG 7690:[DB07863 DB00220] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00220|Nelfinavir CYP2B6;CYP2C19;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;CYP2C9;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0042493| response to drug UGT1A1;PPARG;ABCB1;ABCG2 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP2D6 GO:0042594| response to starvation UGT1A1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;NCOA2;SLCO1A2;SLCO1B3;ABCB11;RXRA;SLCO1B1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 7691:[DB07863 DB00867] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0007165| signal transduction PPARG;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;ADRB2;PPARG;NCOA2 GO:0009409| response to cold PPARG;ADRB2 7692:[DB07863 DB00169] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP11A1;CYP2D6 GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;NCOA2;PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG;RXRA GO:0006351| transcription, DNA-dependent VDR;NCOA2;RXRA;PPARG GO:0008203| cholesterol metabolic process RXRA;CYP11A1 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;VDR GO:0006766| vitamin metabolic process RXRA;CYP2R1 GO:0042493| response to drug PPARG;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;VDR GO:0007165| signal transduction VDR;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0008285| negative regulation of cell proliferation PPARG;VDR GO:0010033| response to organic substance CYP1A1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1 7693:[DB07863 DB11901] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG;RXRA GO:0001701| in utero embryonic development RXRA;AR GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG;RXRA GO:0042493| response to drug GABRG3;ABCG2;ABCB1;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;AR GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;AR GO:0043401| steroid hormone mediated signaling pathway AR;RXRA;PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;AR GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B1 GO:0007165| signal transduction GABRP;PPARG;GABRA6;GABRD;GABRA5;GABRB1;GABRQ;GABRE;AR;GABRB3 7694:[DB07863 DB01586] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0030855| epithelial cell differentiation AKR1C2;PPARG GO:0014070| response to organic cyclic compound ABCC4;PPARG GO:0010033| response to organic substance ABCC4;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0015721| bile acid and bile salt transport RXRA;ABCB11;NCOA2;SLCO1A2;NR1H4;SLC10A1;SLC10A2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;AKR1C2 GO:0007165| signal transduction NR1H4;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0042593| glucose homeostasis PPARG;NR1H4 GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR1H4;RXRA;PPARG GO:0042493| response to drug ABCC2;ABCC4;CYP2E1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1H4 GO:0016032| viral reproduction RXRA;SLC10A1 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1H4 GO:0006351| transcription, DNA-dependent NR1H4;NCOA2;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1H4;PPARG;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter NR1H4;RXRA;PPARG GO:0006629| lipid metabolic process PPARG;AKR1C2 GO:0045087| innate immune response PPARG;NR1H4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;NCOA2;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR1H4 7695:[DB07863 DB00880] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways GO:0010033| response to organic substance CA2;PPARG GO:0043627| response to estrogen stimulus CA2;PPARG 7696:[DB07863 DB11633] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0010033| response to organic substance KCNA5;PPARG GO:0043010| camera-type eye development RXRA;CACNA1C GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 GO:0042493| response to drug ABCG2;ABCB1;PPARG;KCNJ11 GO:0009612| response to mechanical stimulus PPARG;KCNA5 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG;CYP2D6 GO:0007507| heart development CACNA1C;RXRA;PPARG 7697:[DB07863 DB01229] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01229|Paclitaxel TUBB1;BCL2;NR1I2;MAP4;MAP2;MAPT;CYP3A5;CYP3A7;CYP2C8;CYP3A4;CYP19A1;CYP1B1;ABCB11;ABCB1;ABCC1;ABCC10;SLCO1B3;ABCG2;ABCC2 common genes common pathways GO:0006351| transcription, DNA-dependent RXRA;NR1I2;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR1I2 GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;NR1I2;RXRA;PPARG GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2;RXRA GO:0042493| response to drug ABCB1;ABCC2;ABCG2;BCL2;ABCC1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;NR1I2;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0007165| signal transduction NR1I2;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0006919| activation of caspase activity MAPT;PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;BCL2;CYP1B1 GO:0015721| bile acid and bile salt transport ABCB11;RXRA;SLCO1B3;NCOA2 7698:[DB07863 DB12267] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;INSR GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG GO:0007165| signal transduction ERBB2;EGFR;PPARG;ERBB4;IGF1R;MET;ALK GO:0031100| organ regeneration PPARG;FLT3 GO:0042593| glucose homeostasis PPARG;INSR GO:0033993| response to lipid PPARG;EGFR GO:0014070| response to organic cyclic compound PPARG;EGFR GO:0008285| negative regulation of cell proliferation PPARG;ERBB4 GO:0006351| transcription, DNA-dependent ERBB2;PPARG;RXRA;ERBB4;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ERBB2;EGFR GO:0007623| circadian rhythm NCOA2;EGFR GO:0045165| cell fate commitment ERBB4;PPARG GO:0045087| innate immune response PPARG;ABL1 GO:0007507| heart development ERBB2;RXRA;ERBB4;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;NCOA2;MET;RXRA;PPARG GO:0043065| positive regulation of apoptotic process ABL1;ERBB4;PPARG GO:0006355| regulation of transcription, DNA-dependent ABL1;ERBB2;NCOA2;INSR;PPARG;RXRA;ERBB4 GO:0042493| response to drug ABCG2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent EGFR;ERBB4;RXRA;PPARG;INSR 7699:[DB07863 DB04828] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04828|Zomepirac PTGDR2;CYP3A4;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0007165| signal transduction PPARG;PTGDR2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;PTGDR2 7700:[DB07863 DB00411] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM4;CHRM3;PPARG;CHRM1;CHRM2 GO:0007165| signal transduction CHRM3;CHRM2;PPARG;CHRM1;CHRNA2;CHRM4 GO:0006629| lipid metabolic process PLA2G4A;PPARG 7701:[DB07863 DB00918] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0042493| response to drug HTR1B;CYP2E1;PPARG GO:0007165| signal transduction PPARG;HTR1D;HTR1B GO:0007186| G-protein coupled receptor signaling pathway PPARG;HTR1D;HTR1B 7702:[DB07863 DB00957] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007165| signal transduction PPARG;ESR1;PGR;AR GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0043627| response to estrogen stimulus PPARG;ESR1;ABCC2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;ESR1;PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PGR;AR;RXRA;PPARG;ESR1 GO:0006351| transcription, DNA-dependent AR;PGR;RXRA;ESR1;PPARG;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2;AR;PGR GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2;AR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;RXRA;AR GO:0042493| response to drug PPARG;ABCC2 GO:0006355| regulation of transcription, DNA-dependent AR;PGR;RXRA;PPARG;ESR1;NCOA2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG;RXRA;PGR;AR GO:0001701| in utero embryonic development RXRA;AR 7703:[DB07863 DB04860] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04860|Isatoribine TLR7 common genes common pathways GO:0045087| innate immune response TLR7;PPARG GO:0007165| signal transduction TLR7;PPARG 7704:[DB07863 DB00841] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0043627| response to estrogen stimulus ESR1;PPARG;COMT GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0014070| response to organic cyclic compound COMT;PPARG GO:0007165| signal transduction ADRA1B;ADRB1;ADRA1A;ADRB2;PPARG;ESR1;ADRA1D GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0007186| G-protein coupled receptor signaling pathway ADRB1;ADRA1A;ADRA1B;ADRA1D;PPARG;ADRB2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG;RXRA GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1;RXRA GO:0042493| response to drug ADRA1A;PPARG;COMT GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;ESR1;ADRB2;RXRA GO:0009409| response to cold ADRB2;PPARG;ADRB1 GO:0006351| transcription, DNA-dependent RXRA;PPARG;ESR1;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ESR1 7705:[DB07863 DB11817] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0043388| positive regulation of DNA binding JAK2;PPARG GO:0007165| signal transduction PTK2B;JAK2;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;JAK2 GO:0015721| bile acid and bile salt transport RXRA;SLCO1B3;NCOA2 GO:0008285| negative regulation of cell proliferation PTK2B;PPARG;JAK2 GO:0006919| activation of caspase activity JAK2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;JAK2 GO:0009612| response to mechanical stimulus PPARG;PTK2B GO:0071300| cellular response to retinoic acid PTK2B;PPARG GO:0045087| innate immune response JAK3;PPARG;JAK2;PTK2B;JAK1 GO:0035902| response to immobilization stress PPARG;PTK2B GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;JAK2 GO:0042493| response to drug PPARG;ABCG2;PTK2B 7706:[DB07863 DB08808] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0009409| response to cold PPARG;ADRB2;ADRB1;ADRB3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;ADRB2;PPARG GO:0007165| signal transduction ADRB1;ADRB3;PPARG;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway ADRB3;ADRB1;ADRB2;PPARG 7707:[DB07863 DB14059] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0006351| transcription, DNA-dependent NCOA2;RELA;RXRA;NFKB2;PPARG;NFKB1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NFKB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB2;RXRA;PPARG;NCOA2;RELA;NFKB1 GO:0045087| innate immune response NFKB2;PPARG;NFKB1 GO:0006629| lipid metabolic process PTGS2;PPARG GO:1901522| RELA;RXRA GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;NFKB2;PPARG;NCOA2;RELA;NFKB1 GO:0009612| response to mechanical stimulus PPARG;RELA GO:0061614| RELA;PPARG GO:0042493| response to drug RELA;PTGS2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NFKB2;RXRA;RELA;NCOA2;NFKB1 GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;RELA;RXRA;PPARG GO:0016032| viral reproduction RXRA;RELA GO:0007566| embryo implantation RXRA;PTGS2 GO:0007165| signal transduction NFKB1;NFKB2;PPARG GO:0014070| response to organic cyclic compound PTGS2;RELA;PPARG GO:0048511| rhythmic process NCOA2;NFKB2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2;RELA GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;RELA;PPARG;NFKB1 GO:0008217| regulation of blood pressure PPARG;PTGS2 7708:[DB07863 DB01309] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01309|Insulin Glulisine INSR common genes common pathways GO:0042593| glucose homeostasis INSR;PPARG GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG GO:0032869| cellular response to insulin stimulus PPARG;INSR GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;INSR GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG;RXRA 7709:[DB07863 DB00309] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 7710:[DB07863 DB00625] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00625|Efavirenz pol;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP2C8;UGT1A1;ALB;ABCB11;SLC22A1 common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;ABCB11;NCOA2 GO:0010033| response to organic substance PPARG;UGT1A1;CYP1A2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP2C9;PPARG;CYP3A4 GO:0042594| response to starvation UGT1A1;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042493| response to drug PPARG;UGT1A1;CYP1A2 7711:[DB07863 DB00674] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0007165| signal transduction CHRNE;CHRNB4;CHRNB1;CHRNA1;CHRNA6;CHRNA9;PPARG;CHRNG;CHRNB2;CHRNA7;CHRNA2;CHRNB3;CHRNA10;CHRNA3;CHRNA4;CHRNA5;CHRND GO:0007584| response to nutrient PPARG;BCHE GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2D6 GO:0042493| response to drug PPARG;BCHE 7712:[DB07863 DB06153] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR1B;ADRA1A;ADRA2A;HTR2C;HTR2B;ADRA1B;ADRA1D;HRH1;CHRM3;HTR1D;ADRA2C;CHRM1;HTR1A;PPARG;CHRM2;HTR2A;ADRA2B GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA1B;ADRA2A GO:0007165| signal transduction HRH1;CHRM3;HTR1D;ADRA1D;HTR2A;ADRA2B;CHRM2;HTR1A;PPARG;ADRA2C;CHRM1;HTR1B;ADRA1A;HTR2C;HTR2B;ADRA1B;ADRA2A GO:0042493| response to drug HTR2B;HTR2C;HTR1B;ADRA1A;HTR2A;PPARG GO:0016032| viral reproduction RXRA;HTR2A GO:0006629| lipid metabolic process UGT2B10;PPARG GO:0007507| heart development RXRA;PPARG;HTR2B 7713:[DB07863 DB09129] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09129|Chromic chloride INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;INSR;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent INSR;RXRA;PPARG GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG GO:0032869| cellular response to insulin stimulus INSR;PPARG GO:0042593| glucose homeostasis INSR;PPARG 7714:[DB07863 DB00384] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP1A2 GO:0042493| response to drug CYP1A2;PPARG 7715:[DB07863 DB08811] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;PDE2A;PDE4A;PDE3A;PDE10A GO:0007186| G-protein coupled receptor signaling pathway PDE10A;PPARG;PDE3A;PDE2A;PDE4A GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PDE2A;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG;PDE3A GO:0030224| monocyte differentiation PPARG;PDE2A GO:0042493| response to drug PDE3A;PPARG 7716:[DB07863 DB01077] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 7717:[DB07863 DB00942] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00942|Cycrimine CHRM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM1;PPARG GO:0007165| signal transduction CHRM1;PPARG 7718:[DB07863 DB08860] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0042493| response to drug ABCC2;ABCG2;ABCB1;PPARG GO:0016032| viral reproduction RXRA;SLC10A1 GO:0008203| cholesterol metabolic process RXRA;HMGCR GO:0006629| lipid metabolic process PPARG;CYP2C9;HMGCR;UGT2B7 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0007584| response to nutrient HMGCR;PPARG GO:0015721| bile acid and bile salt transport SLC10A1;ALB;SLCO2B1;NCOA2;ABCB11;RXRA;SLCO1B1;SLCO1B3 GO:0019216| regulation of lipid metabolic process PPARG;RXRA;HMGCR;NCOA2 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 7719:[DB07863 DB12010] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0030224| monocyte differentiation CSF1R;PPARG GO:0006355| regulation of transcription, DNA-dependent PDPK1;TXK;ACVR1B;ERBB4;RXRA;PAK6;FGFR1;PPARG;MAPK13;PKN1;MAPK14;PKN2;MAP3K9;PRKAA2;INSR;CSNK2A1;CSNK2A2;NCOA2;HIPK3;ERN1;HIPK2;EIF2AK2;ERBB2;TGFBR1;DAPK3;ABL1;CHEK2;BTK;MAP2K6;PRKCQ;PRKAA1 GO:0042493| response to drug PTK2B;ABCG2;RET;SRC;MAP2K6;LCK;FYN;PPARG;NTRK1;TGFBR2;LYN;UGT1A1;CDK1;CDK4 GO:0045893| positive regulation of transcription, DNA-dependent IKBKB;ERBB4;IRAK1;RXRA;PPARG;INSR;MAP3K2;NEK4;ACVR1;HIPK2;CAMKK2;TGFBR1;DYRK1B;CHEK2;EGFR;MAP2K2;SRC;MAP2K3;RET GO:0001701| in utero embryonic development TGFBR2;RXRA;ACVR1B;FGFR1;ACVR1;FGFR2;TGFBR1;TIE1 GO:0042752| regulation of circadian rhythm PPARG;ROCK2;MAPK9;PRKAA2;PRKCG;MAPK10;PRKAA1 GO:0006367| transcription initiation from RNA polymerase II promoter CDK4;CDK1;RXRA;PPARG GO:0016525| negative regulation of angiogenesis TEK;TIE1;PPARG;ROCK2;PLK2 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;FGFR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;HIPK2;JAK2;STK3;DDR2;PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus SYK;PPARG GO:0016032| viral reproduction RIPK1;EIF2AK2;TBK1;SRC;LCK;KDR;PDGFRA;HCK;FYN;PAK2;LYN;EIF2AK4;SYK;IRAK1;RXRA;EPHA2;DYRK1A;AXL;TYRO3 GO:0032526| response to retinoic acid PDGFRB;PPARG;RXRA;TIE1;CLK2 GO:0055010| ventricular cardiac muscle tissue morphogenesis FGFR2;RXRA GO:0048469| cell maturation BTK;FGFR1;PPARG;AXL GO:0006351| transcription, DNA-dependent MAP2K6;BTK;PRKAA1;EIF2AK2;ERBB2;CHEK2;DAPK3;CSNK2A1;CSNK2A2;NCOA2;HIPK3;ERN1;HIPK2;PDPK1;ERBB4;RXRA;TXK;MAPK13;PKN1;FGFR1;PPARG;PKN2;MAP3K9;PRKAA2;MAPK14 GO:0006357| regulation of transcription from RNA polymerase II promoter PKN1;PPARG;MAPK14;CAMK2D;RXRA;TXK;KIT;EGFR;ERBB2 GO:0007623| circadian rhythm GSK3B;EGFR;NTRK3;NTRK2;NTRK1;CDK4;DYRK1A;NCOA2 GO:0008203| cholesterol metabolic process PRKAA2;RXRA;PRKAA1 GO:0030308| negative regulation of cell growth ACVR1B;BMPR2;PPARG;TNK1 GO:0045165| cell fate commitment PPARG;ERBB4;FGFR2 GO:0007507| heart development MAP2K5;TGFBR1;ERBB2;TEK;ERBB4;TGFBR2;RXRA;NTRK3;PPARG;RAF1;ACVR1;CDKL1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MAP2K5;FRK;AURKB;PLK1;FGFR2;NCOA2;PLK3;HIPK2;RXRA;FGFR1;PPARG GO:0045087| innate immune response CSF1R;SRMS;LCK;BTK;HCK;ITK;MATK;JAK1;SRC;FRK;MAP4K2;EIF2AK2;TYK2;CSK;TBK1;PRKD1;TEC;PTK2B;ABL1;RIOK3;MST1R;YES1;IKBKE;AXL;BLK;TNK1;IRAK4;BMX;TNK2;PIK3CD;JAK2;PTK6;FES;LYN;SYK;ABL2;IRAK1;JAK3;PTK2;IKBKB;FYN;RIPK2;PIK3CG;PPARG;FER;FGR;ZAP70 GO:0035902| response to immobilization stress PTK2B;PPARG GO:0006629| lipid metabolic process PRKAA2;CYP3A4;PPARG;PRKAG2;PRKAG1;PRKAB2;PRKAG3;PRKAB1;PRKAA1 GO:0019048| virus-host interaction RXRA;HIPK2 GO:0042594| response to starvation PPARG;UGT1A1;ULK1;ULK2 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter BMPR2;IKBKB;TXK;ACVR1B;RXRA;PPARG;CASK;RIPK2;MAPK14;RPS6KA3;RAF1;NCOA2;RPS6KA1;MET;ACVR1;STK16;HIPK2;MAP2K5;PRKD1;BMPR1B;TBK1;FGFR2;CAMK1;MAPK7;YES1;RIPK1;EGFR GO:0043065| positive regulation of apoptotic process SRC;MAP3K11;MAP3K10;MAP2K6;STK17A;MELK;TGFBR1;DAPK3;ABL1;RIPK1;JAK2;CDK4;STK3;LATS1;PPARG;RIPK2;NTRK3;MAPK9;PDGFRB;MAP3K9;EPHA7;ERBB4;CAMK1D GO:0009612| response to mechanical stimulus PTK2B;SRC;PPARG;MAPK9;TGFBR2 GO:0071300| cellular response to retinoic acid PTK2B;FGFR2;YES1;RET;LYN;ABL2;PPARG;LTK;NTRK3;EPHA3;PTK6 GO:0030855| epithelial cell differentiation FGFR2;PPARG;CDK1 GO:0014070| response to organic cyclic compound EGFR;CDK1;UGT1A1;LYN;TGFBR2;PPARG;PDGFRB GO:0006919| activation of caspase activity RET;LCK;RIPK1;JAK2;PPARG GO:0048511| rhythmic process CSNK2A1;NCOA2;ROCK2;MAPK9;PRKAA2;PPARG;PRKAA1;SIK1;GSK3B;MAPK10;PRKCG GO:0007584| response to nutrient UGT1A1;MTOR;PPARG;TGFBR2 GO:0048714| positive regulation of oligodendrocyte differentiation MTOR;PPARG GO:0043627| response to estrogen stimulus TEK;PDGFRB;PPARG;TGFBR2 GO:0031000| response to caffeine PPARG;PRKAA1 GO:0008217| regulation of blood pressure PPARG;STK39 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;SRC;MAP3K10 GO:0010033| response to organic substance TGFBR2;PPARG;PAK1;CDK4;UGT1A1;BTK;CLK2;TEK GO:0008285| negative regulation of cell proliferation PTK2B;FRK;CSK;EIF2AK2;CSF1R;PPARG;LYN;NTRK1;TGFBR2;ERBB4;ADORA3;JAK2;DDR1;STK3;EIF2AK1;RAF1 GO:0071380| cellular response to prostaglandin E stimulus PRKAA2;PPARG;PRKCE;PRKAA1 GO:0045600| positive regulation of fat cell differentiation STK3;PPARG GO:0001890| placenta development PPARG;MAPK14;RXRA;PTK2;MAP3K4 GO:0019395| fatty acid oxidation MAPK14;PPARG;PRKAA1 GO:0032869| cellular response to insulin stimulus SRC;PRKCI;PPARG;FER;PAK1;PDPK1;CDK4;INSR;GSK3A GO:0007186| G-protein coupled receptor signaling pathway ADORA3;PDGFRB;ROCK2;PIK3CG;PPARG;INSR;JAK2 GO:0019216| regulation of lipid metabolic process UGT1A9;NCOA2;PPARG;PRKCE;RXRA GO:0007566| embryo implantation DDR1;TGFBR2;RXRA GO:0001893| maternal placenta development RXRA;BMPR2 GO:0007165| signal transduction MAPK7;LIMK1;MAPK10;PTK2B;PRKD1;ULK1;TEK;TIE1;STK24;PRKAA1;BRAF;EGFR;MAP3K10;MAP2K6;ULK2;MAPK14;RPS6KA3;FER;PDGFRB;PRKAA2;MAP3K6;PAK2;PPARG;PKN1;RIPK2;ADORA3;IRAK1;LYN;PIK3CD;JAK2;CSNK1A1;BMX;PDE5A;PRKACB;IRAK4;MTOR;RPS6KA1;TYRO3;RPS6KA6;STK3;PRKCD;PAK5;TGFBR1;PRKAB2;CAMK1;RIPK1;MST1R;ERBB2;PRKAB1;MAP2K5;CDKL2;SRC;MAP2K3;RET;MAPKAPK5;ITK;KIT;CSF1R;PKN2;LTK;DDR2;PRKCE;ACVR1B;ERBB4;ABL2;PI4KB;ICK;IRAK3;DAPK1;TNK2;PRKG2;PRKAG1;PAK4;CAMK2B;MET;CSNK2A1;CDK4;RAF1;AXL;ALK GO:0042593| glucose homeostasis PRKAA1;PRKAA2;PPARG;INSR GO:0031100| organ regeneration CDK1;CDK4;AXL;TGFBR2;FLT3;UGT1A1;PPARG GO:0043010| camera-type eye development BMPR1B;RXRA GO:0033993| response to lipid PDGFRB;PPARG;EGFR GO:0043388| positive regulation of DNA binding PPARG;JAK2;HIPK2 GO:0032870| cellular response to hormone stimulus SIK2;NCOA2;UGT1A1;SIK1 7720:[DB07863 DB00690] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00690|Flurazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP2E1;CYP2A6;CYP3A4;ABCB1;SLC22A2 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1;ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007165| signal transduction GABRD;PPARG;GABRP;GABRR2;GABRA5;GABRA6;GABRE;GABRQ;GABRB1;GABRB3 7721:[DB07863 DB04846] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0009409| response to cold ADRB3;ADRB1;PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RXRA;PPARG;NCOA2 GO:0007165| signal transduction ADRB1;ADRB3;ADRA2A;PPARG;ADRB2;ADRA2B;ADRA2C GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway ADRA2C;ADRA2B;ADRB2;PPARG;ADRA2A;ADRB3;ADRB1 7722:[DB07863 DB00896] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;PPARG GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG;RXRA;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C1 7723:[DB07863 DB06789] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent PGR;NCOA2;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;PGR GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;PGR GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;PGR GO:0007165| signal transduction PGR;PPARG 7724:[DB07863 DB11827] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0010033| response to organic substance UGT1A1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;UGT1A9;RXRA;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug PPARG;UGT1A1;ABCG2;ABCB1 GO:0006629| lipid metabolic process UGT2B7;PPARG GO:0042594| response to starvation UGT1A1;PPARG 7725:[DB07863 DB00584] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1A2 GO:0008217| regulation of blood pressure ACE;PPARG GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7726:[DB07863 DB00485] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 7727:[DB07863 DB12070] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways GO:0042493| response to drug PPARG;UGT1A1;ABCG2;ABCC2;ABCB1 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4 GO:0042594| response to starvation UGT1A1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;SLCO1B3;NCOA2;RXRA GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2;ABCC2 7728:[DB07863 DB00520] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1B1;SLCO1B3 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug ABCB1;PPARG 7729:[DB07863 DB05708] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042493| response to drug CYP1A2;CYP2E1;PPARG GO:0007165| signal transduction CHRNA7;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG 7730:[DB07863 DB00180] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction PPARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;RXRA;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG;RXRA;NCOA2 7731:[DB07863 DB06716] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0007165| signal transduction GABRB3;PPARG 7732:[DB07863 DB00641] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;ITGB2 GO:0042493| response to drug PPARG;UGT1A1;ABCC2;ABCB1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process UGT2B7;CYP3A4;HMGCR;CYP2D6;PPARG;CYP2C9 GO:0008203| cholesterol metabolic process HMGCR;RXRA GO:0007584| response to nutrient HMGCR;PPARG;UGT1A1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0010033| response to organic substance UGT1A1;PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;SLCO1A2;RXRA;NCOA2 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0007165| signal transduction PPARG;ITGAL GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2;ABCC2 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;HMGCR 7733:[DB07863 DB00259] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4 7734:[DB07863 DB00683] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00683|Midazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRB1;GABRB3;GABRB2;GABRA6;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP4B1;UGT1A4;CYP2E1;ABCB1;ABCB11 common genes common pathways GO:0007165| signal transduction GABRE;GABRB1;GABRQ;GABRA6;GABRB3;GABRR2;GABRA5;PPARG;GABRD;GABRP GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug ABCB1;PPARG;GABRG3;CYP2E1 7735:[DB07863 DB00306] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;PPARG GO:0007165| signal transduction GABRA6;GABRE;GABRQ;GABRB1;GABRB3;CHRNA7;GRIA2;CHRNA4;GABRD;PPARG;GABRP;GABRA5 7736:[DB07863 DB00279] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0006351| transcription, DNA-dependent THRB;RXRA;PPARG;NCOA2;THRA GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;THRA;THRB GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;RXRA;PPARG;THRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;NCOA2;PPARG;RXRA GO:0007507| heart development RXRA;PPARG;PCNA GO:0009409| response to cold THRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;PPARG;RXRA;THRA;NCOA2 GO:0006355| regulation of transcription, DNA-dependent THRA;NCOA2;PPARG;RXRA;THRB GO:0042493| response to drug PPARG;ABCB1 GO:0006367| transcription initiation from RNA polymerase II promoter THRB;THRA;RXRA;PPARG GO:0016032| viral reproduction RXRA;SLC10A1 GO:0030522| intracellular receptor mediated signaling pathway THRB;THRA;NCOA2 GO:0033993| response to lipid PCNA;PPARG GO:0030855| epithelial cell differentiation PPARG;PCNA GO:0045892| negative regulation of transcription, DNA-dependent THRB;PPARG;NCOA2;THRA GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;SLCO1A2;RXRA;SLCO1C1;NCOA2;ALB;SLC10A1 7737:[DB07863 DB04975] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug PPARG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TOP2A;RXRA GO:0043065| positive regulation of apoptotic process TOP2A;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0048511| rhythmic process PPARG;TOP2A;NCOA2 GO:0010033| response to organic substance PPARG;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 7738:[DB07863 DB00818] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00818|Propofol GABRB2;GABRB3;SCN4A;SCN2A;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP2B6;UGT1A8;UGT1A9;UGT1A1;FAAH;CYP2E1;CYP1B1;CYP1A1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;UGT1A6;ALB common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction GABRA6;GABRQ;GABRB1;GABRE;GABRB3;GABRP;GABRD;PPARG;GABRA5 GO:0019216| regulation of lipid metabolic process UGT1A9;NCOA2;PPARG;CYP1A1;RXRA GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0010033| response to organic substance CYP1A1;PPARG;UGT1A1;CYP1A2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;PPARG;CYP1A1 GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug PPARG;CYP1A1;UGT1A1;GABRG3;CYP2E1;CYP1A2 7739:[DB07863 DB00636] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;PPARA GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG;RXRA GO:0007507| heart development PPARA;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;PPARA GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;RXRA;PPARG;NCOA2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;PPARA GO:0042493| response to drug CYP2E1;PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG;RXRA GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0033189| response to vitamin A CYP1A1;PPARG GO:0032922| circadian regulation of gene expression PPARA;NCOA2 GO:0030522| intracellular receptor mediated signaling pathway PPARA;NCOA2 GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0019216| regulation of lipid metabolic process PPARA;CYP4A11;CYP1A1;PPARG;RXRA;NCOA2 GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0030855| epithelial cell differentiation GSTA2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0048511| rhythmic process PPARA;NCOA2;PPARG GO:0010033| response to organic substance PPARG;CYP1A1 GO:0010887| negative regulation of cholesterol storage PPARG;PPARA 7740:[DB07863 DB05115] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05115|NN344 INSR common genes common pathways GO:0042593| glucose homeostasis PPARG;INSR GO:0032869| cellular response to insulin stimulus INSR;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;INSR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;INSR GO:0006355| regulation of transcription, DNA-dependent NCOA2;INSR;PPARG;RXRA 7741:[DB07863 DB05849] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05849|NCX 950 ADRB2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG GO:0007165| signal transduction PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;ADRB2 GO:0009409| response to cold PPARG;ADRB2 7742:[DB07863 DB04445] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0006629| lipid metabolic process PPARG;SULT2A1 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;SULT2A1 7743:[DB07863 DB00751] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG GO:0007623| circadian rhythm NCOA2;HTR7 GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug PPARG;ABCB1;ADRA1A;HTR2A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007165| signal transduction HTR7;ADRA1A;ADRA2A;PPARG;HRH1;HRH2;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HRH1;HRH2;HTR2A;ADRA1A;HTR7;ADRA2A;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG 7744:[DB07863 DB00805] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway DRD1;CHRM1;HTR2A;DRD2;HTR2C;HTR2B;PPARG GO:0007165| signal transduction DRD1;CHRM1;HTR2A;HTR2C;HTR2B;DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;PPARG GO:0007584| response to nutrient PPARG;SLC6A4 GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;DRD2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007507| heart development RXRA;PPARG;HTR2B GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0042493| response to drug DRD2;HTR2B;HTR2C;PPARG;DRD1;SLC6A4;HTR2A GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA 7745:[DB07863 DB00199] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042493| response to drug CYP1A2;ABCB1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;MLNR GO:0007165| signal transduction PPARG;MLNR GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2;SLCO1B3;ABCB11;SLCO1B1 7746:[DB07863 DB00374] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;PPARD GO:0010033| response to organic substance PPARD;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD GO:0001890| placenta development PPARD;PPARG;RXRA GO:0019395| fatty acid oxidation PPARD;PPARG GO:0007186| G-protein coupled receptor signaling pathway P2RY12;PPARG;PTGIR GO:0007566| embryo implantation RXRA;PPARD GO:0007165| signal transduction PTGIR;PPARG;P2RY12 GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PTGIR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;PPARD GO:0045893| positive regulation of transcription, DNA-dependent PPARD;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;RXRA;PPARG GO:0033189| response to vitamin A PPARD;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;PPARD GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARD;RXRA;PPARG GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0008203| cholesterol metabolic process PPARD;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG;RXRA GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0007507| heart development PPARD;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;PPARD GO:0006629| lipid metabolic process PPARD;PPARG;CYP2C9 7747:[DB07863 DB08899] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0007165| signal transduction AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG;RXRA GO:0001701| in utero embryonic development AR;RXRA GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;AR GO:0042493| response to drug PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;AR GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;RXRA;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;AR GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG;RXRA 7748:[DB07863 DB01134] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0007165| signal transduction NR3C2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C2 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;NR3C2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006351| transcription, DNA-dependent NR3C2;RXRA;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR3C2;PPARG;RXRA 7749:[DB07863 DB00253] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction PPARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;PPARG;RXRA;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG;RXRA 7750:[DB07863 DB01323] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4 7751:[DB07863 DB00939] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0042493| response to drug PTGS2;PPARG GO:0006629| lipid metabolic process PTGS1;PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0015721| bile acid and bile salt transport SLCO1C1;NCOA2;RXRA GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0007566| embryo implantation PTGS2;RXRA 7752:[DB07863 DB01892] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent RXRA;NR1I2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2;NCOA2 GO:0042493| response to drug ABCC2;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG GO:0006351| transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;NR1I2;PPARG;NCOA2 GO:0006629| lipid metabolic process PTGS1;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1B1 GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007165| signal transduction NR1I2;PPARG 7753:[DB07863 DB06754] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06754|Danaparoid SERPINC1 common genes common pathways GO:0007584| response to nutrient PPARG;SERPINC1 7754:[DB07863 DB13346] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;HDAC6;HDAC10 GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2;HDAC6 GO:0007566| embryo implantation RXRA;PTGS2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;HDAC6;HDAC10 GO:0042493| response to drug PTGS2;PPARG GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;HDAC10;HDAC6 GO:0045598| regulation of fat cell differentiation PPARG;HDAC6 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;PTGS2;PTGS1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC10;PPARG;RXRA;NCOA2 7755:[DB07863 DB04920] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways GO:0042493| response to drug PPARG;BCHE;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;PPARG GO:0007507| heart development CACNA1C;PPARG;RXRA GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0007584| response to nutrient PPARG;BCHE GO:0043010| camera-type eye development CACNA1C;RXRA 7756:[DB07863 DB06218] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 7757:[DB07863 DB01006] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 7758:[DB07863 DB13931] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0048511| rhythmic process PPARG;ROCK2;NCOA2 GO:0007165| signal transduction PPARG;ROCK1 GO:0007186| G-protein coupled receptor signaling pathway ROCK2;PPARG;ROCK1 GO:0016525| negative regulation of angiogenesis ROCK1;PPARG;ROCK2 GO:0042752| regulation of circadian rhythm PPARG;ROCK2 7759:[DB07863 DB00257] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I3;NR1I2;RXRA;PPARG;NCOA2 GO:0042493| response to drug PPARG;ABCC2;ABCB1;CYP2E1 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2;NR1I3 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1I2;NR1I3 GO:0008203| cholesterol metabolic process CYP11A1;RXRA GO:0006351| transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2;NR1I3 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR1I2;NR1I3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;NCOA2;RXRA;NR1I2;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;CYP11B1;CYP3A4;CYP11A1 GO:0015721| bile acid and bile salt transport RXRA;ABCC3;NCOA2;ABCB11 GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;NR1I2;PPARG;NCOA2 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0032870| cellular response to hormone stimulus CYP11B1;ABCC2;NCOA2 GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0007165| signal transduction NR1I3;PPARG;NR1I2 7760:[DB07863 DB08865] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0007165| signal transduction PPARG;MET;ALK GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;RXRA;PPARG;NCOA2 GO:0042493| response to drug ABCB1;PPARG 7761:[DB07863 DB08813] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;FOS GO:0007584| response to nutrient PPARG;SERPINC1 GO:0014070| response to organic cyclic compound FOS;PPARG GO:0035902| response to immobilization stress FOS;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter MYC;PPARG;RXRA;NCOA2 GO:0009612| response to mechanical stimulus FOS;PPARG GO:0009409| response to cold FOS;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;FOS;NCOA2;MYC GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;MYC GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;FOS;RXRA;MYC GO:0045893| positive regulation of transcription, DNA-dependent RXRA;FOS;PPARG;MYC GO:0006355| regulation of transcription, DNA-dependent PPARG;FOS;RXRA;NCOA2;MYC GO:0042493| response to drug MYC;PPARG;FOS 7762:[DB07863 DB09082] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;ADRB2 GO:0009409| response to cold ADRB2;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2 GO:0007165| signal transduction PPARG;ADRB2 7763:[DB07863 DB00055] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0016525| negative regulation of angiogenesis PF4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;RXRA;PPARG;PF4;NCOA2 GO:0007623| circadian rhythm NCOA2;SERPINE1 GO:0007165| signal transduction PPARG;THBD GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;PF4 7764:[DB07863 DB01359] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0007165| signal transduction ADRB2;HTR1A;PPARG;HTR1B;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;HTR1A;PPARG;ADRB1;HTR1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;ADRB2 GO:0009409| response to cold PPARG;ADRB1;ADRB2 GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0042493| response to drug HTR1B;PPARG 7765:[DB07863 DB00281] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0007623| circadian rhythm EGFR;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;EGFR GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;RXRA;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;EGFR GO:0042493| response to drug CYP1A2;PPARG;ABCB1 GO:0007165| signal transduction PPARG;EGFR GO:0033993| response to lipid PPARG;EGFR GO:0014070| response to organic cyclic compound CYP1A2;PPARG;EGFR GO:0010033| response to organic substance PPARG;CYP1A2 7766:[DB07863 DB00524] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00524|Metolazone SLC12A3 common genes common pathways 7767:[DB07863 DB01110] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01110|Miconazole NOS3;NOS2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;KCNH2;KCNH6;KCNH7;NR1I2;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP11B1;CYP51A1;CYP19A1;ABCB1 common genes common pathways GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0032870| cellular response to hormone stimulus CYP11B1;NCOA2 GO:0007165| signal transduction PPARG;NR1I2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0008217| regulation of blood pressure CYP11B1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation PPARG;NOS3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;NR1I2;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;KCNMA1 GO:0006629| lipid metabolic process CYP3A4;CYP11B1;CYP51A1;CYP2D6;CYP2C9;PPARG GO:0007623| circadian rhythm NCOA2;NOS2 GO:0008203| cholesterol metabolic process CYP51A1;RXRA GO:0006351| transcription, DNA-dependent NCOA2;NR1I2;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;RXRA GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0001701| in utero embryonic development RXRA;NOS3 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;NR1I2;PPARG GO:0042493| response to drug CYP2E1;ABCB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG 7768:[DB07863 DB00924] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0042493| response to drug PPARG;UGT1A1;HTR2A;CYP1A2 GO:0016032| viral reproduction RXRA;HTR2A GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance CYP1A2;PPARG;UGT1A1 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2A;PPARG GO:0007165| signal transduction HTR2A;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 7769:[DB07863 DB08893] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08893|Mirabegron ADRB3;CYP3A4;CYP2D6;BCHE;ALB;ORM1;ABCB1;SLCO1A2 common genes common pathways GO:0009409| response to cold PPARG;ADRB3 GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4 GO:0042493| response to drug ABCB1;PPARG;BCHE GO:0007165| signal transduction PPARG;ADRB3 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB3 GO:0015721| bile acid and bile salt transport SLCO1A2;RXRA;NCOA2;ALB GO:0008285| negative regulation of cell proliferation BCHE;PPARG GO:0007584| response to nutrient BCHE;PPARG 7770:[DB07863 DB06433] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06433|Tezacitabine RRM1;TYMP common genes common pathways 7771:[DB07863 DB09401] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0030308| negative regulation of cell growth PPARG;BCL2 GO:0043065| positive regulation of apoptotic process BCL2L1;PPARG GO:0042493| response to drug PPARG;BCL2 GO:0001701| in utero embryonic development BCL2L1;RXRA GO:0008285| negative regulation of cell proliferation BCL2;PPARG 7772:[DB07863 DB07348] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 7773:[DB07863 DB08810] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;HTR2A;HTR1A;HTR4 GO:0007165| signal transduction PPARG;HTR2A;HTR1A;HTR4 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0042493| response to drug PPARG;HTR2A GO:0016032| viral reproduction HTR2A;RXRA 7774:[DB07863 DB06154] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;NOS3 GO:0008217| regulation of blood pressure NOS3;PPARG;HBB GO:0007165| signal transduction PPARG;GUCY1A2 GO:0001701| in utero embryonic development RXRA;NOS3 7775:[DB07863 DB05109] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG GO:0006629| lipid metabolic process CYP3A4;PTGS1;PPARG;CYP2C9;CYP2D6 GO:0008217| regulation of blood pressure PPARG;PTGS1 7776:[DB07863 DB01437] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0007165| signal transduction GABRP;PPARG;GABRD;GABRA5;GABRA6;GABRB1;GABRQ;GABRE;GABRB3 GO:0042493| response to drug GABRG3;PPARG GO:0008203| cholesterol metabolic process RXRA;CYP11A1 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP11A1 7777:[DB07863 DB06204] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0010033| response to organic substance PPARG;SLC6A4 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRM1;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;PPARG;OPRK1;HTR3A GO:0042493| response to drug SLC6A4;PPARG;SLC6A2 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;UGT2B7 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 7778:[DB07863 DB09028] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0007165| signal transduction CHRNA6;CHRNA4;CHRNA7;CHRNB2;PPARG;CHRNA3 7779:[DB07863 DB00744] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PTGS1;CYP1A2;CYP3A4;CYP2C9;PPARG GO:0042493| response to drug PPARG;CYP1A2 GO:0019216| regulation of lipid metabolic process UGT1A9;NCOA2;PPARG;RXRA GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0010033| response to organic substance PPARG;CYP1A2 7780:[DB07863 DB06186] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06186|Ipilimumab CTLA4 common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;CTLA4 7781:[DB07863 DB00247] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0007507| heart development RXRA;PPARG;HTR2B GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007623| circadian rhythm NCOA2;HTR7 GO:0016032| viral reproduction HTR2A;RXRA GO:0042493| response to drug HTR2A;HTR1B;HTR2C;HTR2B;PPARG GO:0007165| signal transduction HTR1E;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR2B;HTR2C;PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR1E;HTR1A;HTR2A;HTR2B;HTR2C;HTR1F;HTR1B;HTR7;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C 7782:[DB07863 DB04977] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways GO:0019216| regulation of lipid metabolic process CYP4A11;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug CYP2E1;PPARG 7783:[DB07863 DB06271] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways GO:0007584| response to nutrient PPARG;SERPINC1 7784:[DB07863 DB00367] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;RXRA;PPARG GO:0042493| response to drug PPARG;SRD5A1 GO:0006355| regulation of transcription, DNA-dependent PGR;NCOA2;PPARG;RXRA;AR;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;PGR;ESR1;AR GO:0001701| in utero embryonic development RXRA;AR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;PGR;ESR1;AR GO:0006351| transcription, DNA-dependent ESR1;AR;RXRA;PPARG;NCOA2;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;RXRA;NCOA2;PGR GO:0006629| lipid metabolic process PPARG;CYP3A4;SRD5A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG;RXRA;NCOA2 GO:0014070| response to organic cyclic compound SRD5A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0043627| response to estrogen stimulus SRD5A1;ESR1;PPARG GO:0032869| cellular response to insulin stimulus SRD5A1;PPARG GO:0007165| signal transduction PGR;PPARG;AR;ESR1 7785:[DB07863 DB13956] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes NCOA2 common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;PPARG;CYP1A2 GO:0045475| locomotor rhythm NCOA2 GO:0001890| placenta development HSD17B2;PPARG;RXRA GO:0015721| bile acid and bile salt transport SLCO1C1;NCOA2;RXRA;SLCO2B1;ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0010033| response to organic substance UGT1A1;CYP1A1;PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BECN1;GPER1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;NCOA2 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process NCOA2;PPARG GO:1904017| NCOA2 GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway GPER1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction PPARG;NR1I2;ESR2;ESR1;CHRNA4;GPER1 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;ESR2;ESRRG;ESR1 GO:0042493| response to drug CYP1A2;ABCB1;ABCG2;BECN1;UGT1A1;CYP1A1;PPARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2;ESR2;ESRRG;ESR1 GO:0048384| retinoic acid receptor signaling pathway RXRA;ESRRG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2;ESR1 GO:0016032| viral reproduction BECN1;RXRA GO:0010906| regulation of glucose metabolic process NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0032922| circadian regulation of gene expression NCOA2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:1904706| GPER1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1I2;RXRA;PPARG;ESR2;ESRRG GO:0001701| in utero embryonic development RXRA;HSD17B2 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ESR1 GO:0007623| circadian rhythm NCOA2 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESRRG;RXRA;NR1I2;PPARG;GPER1;ESR1 GO:0006351| transcription, DNA-dependent ESRRG;ESR2;NCOA2;RXRA;NR1I2;PPARG;ESR1 GO:0032526| response to retinoic acid PPARG;RXRA;HSD17B2 GO:0043065| positive regulation of apoptotic process GPER1;PPARG;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GPER1;RXRA;NR1I2;PPARG;NCOA2;ESR2;ESRRG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4;HSD17B2;CYP1A2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0045087| innate immune response GPER1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;NCOA2;PPARG;RXRA;ESR1 7786:[DB07863 DB01193] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;ADRB2 GO:0009409| response to cold ADRB2;PPARG;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB1;ADRB2 GO:0007165| signal transduction ADRB2;ADRB1;PPARG 7787:[DB07863 DB01624] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;DRD2 GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug HTR2A;DRD1;PPARG;DRD2;ADRA1A GO:0007165| signal transduction PPARG;ADRA1A;DRD2;ADRA2A;HRH1;HTR2A;DRD5;DRD1 GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;DRD2;ADRA1A;PPARG;DRD1;DRD5;HTR2A;HRH1 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A 7788:[DB07863 DB00171] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0045087| innate immune response ABL1;PPARG;PIK3CA;TNK2;ABL2 GO:0007507| heart development ACVR1;PPARG;RXRA GO:0006629| lipid metabolic process PRKAA1;ACSL1;PPARG;ABCA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;ACVR1;AKT1;ACVRL1;ACVR1B GO:0043065| positive regulation of apoptotic process AKT1;APAF1;ABL1;PPARG GO:0009612| response to mechanical stimulus ASNS;PPARG GO:0071300| cellular response to retinoic acid PPARG;ABCA1;ABL2 GO:0006351| transcription, DNA-dependent PRKAA1;RXRA;PPARG;NCOA2;PPP5C;CSNK2A1 GO:0008203| cholesterol metabolic process PRKAA1;ABCG1;RXRA;ABCA1 GO:0007623| circadian rhythm NCOA2;ADCY1;ASS1 GO:0030308| negative regulation of cell growth ACVR1B;ACVRL1;PPARG GO:0001701| in utero embryonic development ACVR1;ACVR1B;ACVRL1;RXRA GO:0042752| regulation of circadian rhythm PPARG;PRKAA1;ADCY1 GO:0016525| negative regulation of angiogenesis ABCC8;PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus ABCA1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity AKT1;PPARG GO:0016032| viral reproduction SLC25A4;RXRA GO:0006355| regulation of transcription, DNA-dependent ABCG1;NCOA2;RXRA;PPARG;PRKAA1;ABL1;CSNK2A1;ACVR1B;ACVRL1 GO:0042493| response to drug ABCC4;ABCA1;ABCC8;ABCB1;ADCY1;ABCC2;ACSL1;ABCC1;ABCC6;PPARG;ABCC9 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;ACVRL1;ACVR1;AKT1 GO:0001893| maternal placenta development AKT1;RXRA GO:0007165| signal transduction ABCC9;NAE1;PPARG;ARAF;CSNK2B;ADCY1;PRKAA1;ABCC8;ACVR1B;ABL2;ACVRL1;P2RY11;ALK;AKT1;CSNK2A1;AMHR2;TNK2 GO:0042593| glucose homeostasis PPARG;PRKAA1;AKT1 GO:0033993| response to lipid PPARG;ABCG1 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2;ASNS GO:0032869| cellular response to insulin stimulus AKT1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PIK3CA;AKT1;P2RY11;ABCA1;ADCY1;PPARG GO:0019216| regulation of lipid metabolic process ABCA1;ACSL1;NCOA2;RXRA;PPARG GO:0048511| rhythmic process CSNK2A1;NCOA2;PPARG;PRKAA1;ADCY1 GO:0007584| response to nutrient PPARG;ACSL1;APAF1;ABCA1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0031000| response to caffeine PRKAA1;PPARG GO:0008217| regulation of blood pressure PPARG;ACVRL1 GO:0008285| negative regulation of cell proliferation CSNK2B;PPARG;ACVRL1 GO:0010033| response to organic substance ABCC4;AKT1;ACSL1;ABCG1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration ACVRL1;PPARG;CSNK2B GO:0071380| cellular response to prostaglandin E stimulus AKT1;PRKAA1;PPARG GO:0010887| negative regulation of cholesterol storage ABCG1;PPARG;ABCA1 GO:0045600| positive regulation of fat cell differentiation PPARG;AKT1 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ABCB11 GO:0019395| fatty acid oxidation PPARG;PRKAA1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ABCG1;ABCA1 GO:0014070| response to organic cyclic compound PPARG;ACSL1;ABCC4 GO:0006919| activation of caspase activity APAF1;PPARG 7789:[DB07863 DB05766] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;NCOA2;DRD3 GO:0042493| response to drug PPARG;DRD3;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;DRD3;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA;DRD3 GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0007165| signal transduction CHRM1;DRD2;DRD3;PPARG GO:0019216| regulation of lipid metabolic process DRD3;RXRA;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway CHRM1;DRD2;DRD3;PPARG 7790:[DB07863 DB08883] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;PPARG GO:0007165| signal transduction GRIA1;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG 7791:[DB07863 DB00445] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0042493| response to drug ABCC1;PPARG GO:0006355| regulation of transcription, DNA-dependent CHD1;RXRA;PPARG;NCOA2 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0006357| regulation of transcription from RNA polymerase II promoter CHD1;RXRA;PPARG GO:0006351| transcription, DNA-dependent CHD1;RXRA;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;TOP2A;PPARG;NCOA2 GO:0006629| lipid metabolic process UGT2B7;PPARG;PLA2G4A GO:0048511| rhythmic process PPARG;TOP2A;NCOA2 7792:[DB07863 DB06738] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0019216| regulation of lipid metabolic process UGT1A9;NCOA2;PPARG;RXRA GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0007165| signal transduction OPRK1;PPARG;OPRD1;OPRM1 GO:0042493| response to drug PPARG;GRIN2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;PPARG;RXRA GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;PTGS1;CYP3A4 7793:[DB07863 DB05223] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;HDAC1 GO:0010033| response to organic substance PPARG;HDAC6 GO:0045892| negative regulation of transcription, DNA-dependent HDAC6;HDAC3;HDAC2;NCOA2;HDAC1;PPARG GO:0031000| response to caffeine HDAC2;PPARG;HDAC1 GO:0048714| positive regulation of oligodendrocyte differentiation HDAC1;PPARG;HDAC2 GO:0048511| rhythmic process HDAC1;PPARG;NCOA2;HDAC2 GO:0019216| regulation of lipid metabolic process PPARG;RXRA;NCOA2;HDAC3 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;HDAC1;HDAC2 GO:0042493| response to drug PPARG;HDAC1;HDAC2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;HDAC1;HDAC6;HDAC2;HDAC3 GO:0016032| viral reproduction HDAC1;RXRA GO:0032922| circadian regulation of gene expression HDAC1;NCOA2;HDAC2 GO:0045598| regulation of fat cell differentiation HDAC6;PPARG GO:0006351| transcription, DNA-dependent HDAC2;HDAC3;HDAC6;NCOA2;PPARG;RXRA;HDAC1 GO:0007623| circadian rhythm NCOA2;HDAC3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC2;HDAC3;NCOA2;PPARG;RXRA;HDAC1 GO:0071300| cellular response to retinoic acid PPARG;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC3;HDAC2;NCOA2;RXRA;HDAC1;PPARG 7794:[DB07863 DB12698] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD4;PPARG;RXRA GO:0016032| viral reproduction CD4;CXCR4;RXRA;CCR5 GO:0007186| G-protein coupled receptor signaling pathway CXCR4;CCR5;PPARG GO:0007165| signal transduction PPARG;CCR5;CXCR4;CD4 GO:0048714| positive regulation of oligodendrocyte differentiation CXCR4;PPARG 7795:[DB07863 DB00031] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0007165| signal transduction PPARG;PLAUR;FGA GO:0043388| positive regulation of DNA binding PLAUR;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PLG GO:0010033| response to organic substance CALR;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CALR;NCOA2 GO:0007623| circadian rhythm NCOA2;SERPINE1 GO:0045087| innate immune response FGA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;CALR;NCOA2 GO:0006629| lipid metabolic process PPARG;LRP1 GO:0042953| lipoprotein transport LRP1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;SERPINE1 GO:0042493| response to drug PPARG;CALR GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;CALR;NCOA2 GO:0016032| viral reproduction KRT8;RXRA 7796:[DB07863 DB02187] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007165| signal transduction ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG;RXRA GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;ESR1 GO:0006629| lipid metabolic process PPARG;CYP3A4;HSD17B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;RXRA;PPARG GO:0006351| transcription, DNA-dependent ESR1;NCOA2;PPARG;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA 7797:[DB07863 DB01207] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0042493| response to drug PPARG;TBXA2R GO:0006629| lipid metabolic process PPARG;TBXAS1 GO:0007584| response to nutrient PPARG;TBXA2R GO:0007165| signal transduction TBXA2R;PPARG GO:0007186| G-protein coupled receptor signaling pathway TBXA2R;PPARG 7798:[DB07863 DB01194] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0010033| response to organic substance PPARG;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 7799:[DB07863 DB00240] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RXRA;PPARG GO:0006351| transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;NR3C1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0007165| signal transduction NR3C1;PPARG 7800:[DB07863 DB08910] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08910|Pomalidomide CRBN;TNF;PTGS2;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0007566| embryo implantation PTGS2;RXRA GO:0045994| positive regulation of translational initiation by iron TNF;RXRA GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;TNF;PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;TNF;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2;CYP1A2 GO:0006919| activation of caspase activity PPARG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TNF;RXRA GO:0043065| positive regulation of apoptotic process PPARG;TNF;PTGS2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP1A2;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;RXRA;PPARG;NCOA2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0045893| positive regulation of transcription, DNA-dependent TNF;RXRA;PPARG GO:0042493| response to drug ABCB1;PPARG;PTGS2;CYP1A2 7801:[DB07863 DB00860] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1A2 GO:0007165| signal transduction PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG;RXRA;NCOA2 GO:0042493| response to drug PPARG;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA 7802:[DB07863 DB00846] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RXRA;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RXRA;PPARG GO:0006351| transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;NR3C1 GO:0007165| signal transduction NR3C1;PPARG 7803:[DB07863 DB06209] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0007186| G-protein coupled receptor signaling pathway PPARG;P2RY12 GO:0007165| signal transduction PPARG;P2RY12 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4 7804:[DB07863 DB01125] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01125|Anisindione GGCX common genes common pathways 7805:[DB07863 DB00851] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug CYP1A2;CYP2E1;CYP1A1;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CYP1A1;RXRA 7806:[DB07863 DB00481] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;TFF1 GO:0010033| response to organic substance UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0007165| signal transduction ESR2;PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG;RXRA;ESR2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0042493| response to drug PPARG;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;PPARG;RXRA;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;ESR2;ESR1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0035902| response to immobilization stress TFF1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ESR1 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG;RXRA GO:0006351| transcription, DNA-dependent ESR1;ESR2;RXRA;PPARG;NCOA2 7807:[DB07863 DB01009] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0006629| lipid metabolic process PTGS1;PTGS2;PPARG;CYP2C9 GO:0042594| response to starvation PPARG;UGT1A1 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0042493| response to drug ABCC4;PTGS2;PPARG;UGT1A1 GO:0007165| signal transduction PPARG;CXCR1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007566| embryo implantation RXRA;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CXCR1 GO:0010033| response to organic substance ABCC4;PTGS2;UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA;SLCO1A2 GO:0014070| response to organic cyclic compound PTGS2;ABCC4;PPARG;UGT1A1 7808:[DB07863 DB01536] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways GO:0071379| cellular response to prostaglandin stimulus AKR1C3;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;HSD17B1 GO:0007584| response to nutrient PPARG;AKR1C3 GO:0007186| G-protein coupled receptor signaling pathway AKR1C3;PPARG 7809:[DB07863 DB11967] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0045994| positive regulation of translational initiation by iron RXRA;TNF GO:0007566| embryo implantation IL1B;RXRA GO:0032966| negative regulation of collagen biosynthetic process IL6;PPARG GO:0007165| signal transduction PPARG;IL1B GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG;UGT1A1 GO:0006919| activation of caspase activity PPARG;TNF GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;TNF GO:0008285| negative regulation of cell proliferation PPARG;IL6;IL1B GO:0010033| response to organic substance TNF;PPARG;UGT1A1;CYP1A2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TNF;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;TNF;IL6;IL1B GO:0043065| positive regulation of apoptotic process PPARG;TNF;IL6 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;TNF;IL1B;IL6;MAP2K2 GO:0042493| response to drug CYP1A2;UGT1A1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;IL6;TNF;PPARG 7810:[DB07863 DB00562] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways GO:0042493| response to drug CA9;PPARG GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010033| response to organic substance CA2;PPARG 7811:[DB07863 DB01370] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0008285| negative regulation of cell proliferation APP;PPARG GO:0008217| regulation of blood pressure ATP1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway APP;PPARG GO:0042493| response to drug PPARG;ATP1A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;PPARG GO:0008203| cholesterol metabolic process APP;RXRA GO:0043065| positive regulation of apoptotic process PPARG;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;NCOA2;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;APP;RXRA;PPARG GO:0045087| innate immune response PPARG;APP 7812:[DB07863 DB01114] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0042493| response to drug SLC6A2;PPARG;SLC6A3;SLC6A4 GO:0007165| signal transduction PPARG;HRH1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;HRH1 GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 GO:0014070| response to organic cyclic compound PPARG;SLC6A3 7813:[DB07863 DB00054] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:0016032| viral reproduction ITGB3;FCGR2B;RXRA GO:0045087| innate immune response C1S;C1QC;C1QA;PPARG;C1R;C1QB;FCGR1A GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ITGB3 GO:0007165| signal transduction PPARG;FCGR2B;FCGR1A;FCGR2C 7814:[DB07863 DB00461] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0010033| response to organic substance PTGS2;CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0007566| embryo implantation PTGS2;RXRA GO:0042493| response to drug PPARG;PTGS2;CYP1A2 GO:0009612| response to mechanical stimulus PPARG;MPO GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PTGS2;CYP1A2;PTGS1;PPARG 7815:[DB07863 DB00005] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0016032| viral reproduction FCGR2B;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0042493| response to drug LTA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;TNF GO:0045087| innate immune response PPARG;C1QB;C1R;FCGR1A;C1S;C1QC;C1QA GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;TNF GO:0043065| positive regulation of apoptotic process PPARG;TNF;LTA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;TNF;PPARG GO:0007584| response to nutrient PPARG;LTA GO:0010033| response to organic substance PPARG;TNF GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;TNF GO:0006919| activation of caspase activity PPARG;TNF GO:0007165| signal transduction FCGR2C;FCGR1A;FCGR2B;PPARG;LTA GO:0045994| positive regulation of translational initiation by iron RXRA;TNF 7816:[DB07863 DB00310] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00310|Chlorthalidone SLC12A1 common genes common pathways 7817:[DB07863 DB00216] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0007165| signal transduction HTR1A;HTR1D;HTR1E;PPARG;HTR1F;HTR2B;HTR7;HTR1B GO:0007186| G-protein coupled receptor signaling pathway HTR1E;HTR1A;HTR1D;HTR1F;HTR2B;HTR7;HTR1B;PPARG GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;CYP3A4;PTGS1 GO:0007507| heart development PPARG;RXRA;HTR2B GO:0007623| circadian rhythm HTR7;NCOA2 GO:0042493| response to drug PPARG;ABCB1;HTR1B;HTR2B 7818:[DB07863 DB00975] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;RCAN1 GO:0042493| response to drug ABCC4;ADA;PPARG;ABCB1 GO:0001701| in utero embryonic development RXRA;ADA GO:0014070| response to organic cyclic compound ABCC4;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO2B1;SLCO1B1;ABCB11;SLCO1B3 GO:0001890| placenta development ADA;PPARG;RXRA GO:0010033| response to organic substance ABCC4;PPARG GO:0007186| G-protein coupled receptor signaling pathway PDE10A;PDE4A;PPARG GO:0007165| signal transduction PDE5A;PPARG;RCAN1;PDE10A;PDE4A 7819:[DB07863 DB00528] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 7820:[DB07863 DB05075] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0016032| viral reproduction KDR;RXRA GO:0045087| innate immune response PPARG;CSK GO:0008285| negative regulation of cell proliferation PPARG;CSK 7821:[DB07863 DB01100] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01100|Pimozide DRD2;DRD3;KCNH2;CALM1;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0007186| G-protein coupled receptor signaling pathway CALM1;PPARG;DRD3;DRD2 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;DRD3 GO:0007165| signal transduction PPARG;DRD3;DRD2 GO:0042493| response to drug CYP1A2;CYP2E1;DRD2;ABCB1;DRD3;PPARG GO:0032922| circadian regulation of gene expression DRD2;NCOA2;DRD3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PPARG;CYP2D6 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG;DRD2 7822:[DB07863 DB00983] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6 GO:0009409| response to cold ADRB2;PPARG;ADRB1;ADRB3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;RXRA;PPARG;NCOA2 GO:0007165| signal transduction ADRB2;PPARG;ADRB3;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG;ADRB1;ADRB3 7823:[DB07863 DB00763] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042493| response to drug PPARG;CYP2E1;CYP1A2 7824:[DB07863 DB08868] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC1 GO:0048511| rhythmic process NCOA2;HDAC1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;HDAC1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;HDAC1;PPARG GO:0008217| regulation of blood pressure PPARG;CYP4F2 GO:0031000| response to caffeine PPARG;HDAC1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;S1PR5 GO:0007165| signal transduction S1PR5;PPARG;SPHK1 GO:0042493| response to drug CYP2E1;HDAC1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;HDAC1;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;HDAC1;RXRA GO:0032922| circadian regulation of gene expression HDAC1;NCOA2 GO:0016032| viral reproduction RXRA;HDAC1 GO:0006351| transcription, DNA-dependent NCOA2;HDAC1;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;HDAC1;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;HDAC1;PPARG;NCOA2 7825:[DB07863 DB00575] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00575|Clonidine ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP3A5;SLC22A3;SLC22A5;SLC22A4;ABCB1 common genes common pathways GO:0007165| signal transduction ADRA1B;ADRA2C;ADRA2B;ADRA1A;ADRA2A;ADRA1D;PPARG GO:0042593| glucose homeostasis PPARG;ADRA2A;ADRA1B GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;ADRA2C;ADRA2B;ADRA2A;ADRA1A;PPARG;ADRA1D GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0042493| response to drug CYP1A2;ABCB1;ADRA1A;CYP1A1;PPARG 7826:[DB07863 DB08907] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCC2;ABCB1 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0019216| regulation of lipid metabolic process NCOA2;UGT1A9;RXRA;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 7827:[DB07863 DB12248] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12248|Tulobuterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;ADRB2 GO:0009409| response to cold ADRB2;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG GO:0007165| signal transduction PPARG;ADRB2 7828:[DB07863 DB11575] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA;SLCO1B3;SLCO1B1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCB1 7829:[DB07863 DB14542] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0042493| response to drug ABCG2;ANXA1;HSD11B2;ABCB1;PPARG GO:0045087| innate immune response PPARG;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP11B1;CYP11B2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0043065| positive regulation of apoptotic process ANXA1;PPARG GO:0006351| transcription, DNA-dependent NR3C1;RXRA;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0008217| regulation of blood pressure PPARG;CYP11B1 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;RXRA GO:0014070| response to organic cyclic compound PPARG;ANXA1 GO:0007165| signal transduction NR3C1;ANXA1;PPARG GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ANXA1;PPARG 7830:[DB07863 DB11574] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCB1 7831:[DB07863 DB00583] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0019216| regulation of lipid metabolic process CPT1A;NCOA2;CPT2;RXRA;PPARG GO:0006919| activation of caspase activity XDH;PPARG GO:0014070| response to organic cyclic compound PPARG;CPT1A GO:0030855| epithelial cell differentiation PPARG;CPT1A;CES1 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B1 GO:0007623| circadian rhythm CPT1A;NCOA2 GO:0009612| response to mechanical stimulus PPARG;MPO GO:0006629| lipid metabolic process CPT2;PPARG;CROT;CPT1A;CRAT GO:0042493| response to drug PPARG;CPT1A 7832:[DB07863 DB05281] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0008285| negative regulation of cell proliferation BCL2;PPARG GO:0042493| response to drug PPARG;BCL2 GO:0030308| negative regulation of cell growth BCL2;PPARG 7833:[DB07863 DB00158] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0042493| response to drug ABCC4;GGH;MTHFR;CYP2E1;ABCG2;PPARG GO:0015721| bile acid and bile salt transport ALB;NCOA2;ABCC3;RXRA GO:0010033| response to organic substance ABCC4;PPARG GO:0014070| response to organic cyclic compound PPARG;ABCC4 7834:[DB07863 DB00901] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00901|Bitolterol ADRB2 common genes common pathways GO:0009409| response to cold ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2 GO:0007165| signal transduction PPARG;ADRB2 7835:[DB07863 DB01041] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01041|Thalidomide CRBN;TNF;NFKB1;FGFR2;PTGS2;ORM1;ORM2;CYP2C19;CYP1A1;CYP2E1;CYP2C9;PTGS1;PTGS2;CYP3A5 common genes common pathways GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0060687| regulation of branching involved in prostate gland morphogenesis FGFR2;RXRA GO:0001701| in utero embryonic development RXRA;FGFR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;TNF;PPARG;NFKB1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;RXRA;PPARG;NCOA2 GO:0042493| response to drug PPARG;CYP1A1;PTGS2;CYP2E1 GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;PPARG GO:0045165| cell fate commitment FGFR2;PPARG GO:0045087| innate immune response PPARG;NFKB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR2;NFKB1;PPARG;RXRA;TNF;NCOA2 GO:0071300| cellular response to retinoic acid PPARG;FGFR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;RXRA;NCOA2;FGFR2;NFKB1 GO:0043065| positive regulation of apoptotic process PTGS2;TNF;PPARG GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;NFKB1 GO:0055010| ventricular cardiac muscle tissue morphogenesis RXRA;FGFR2 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NFKB1 GO:0008217| regulation of blood pressure PPARG;PTGS2;PTGS1 GO:0045892| negative regulation of transcription, DNA-dependent NFKB1;NCOA2;TNF;PPARG GO:0010033| response to organic substance CYP1A1;PPARG;TNF;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0030855| epithelial cell differentiation PPARG;FGFR2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;PTGS2 GO:0006919| activation of caspase activity PPARG;TNF GO:0007165| signal transduction PPARG;NFKB1 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0045994| positive regulation of translational initiation by iron TNF;RXRA GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0007566| embryo implantation RXRA;PTGS2 7836:[DB07863 DB01303] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0006351| transcription, DNA-dependent HDAC2;RXRA;PPARG;NCOA2 GO:0071300| cellular response to retinoic acid PPARG;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;HDAC2 GO:0006629| lipid metabolic process PPARG;PDE3A;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;HDAC2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;HDAC2 GO:0042493| response to drug CYP1A2;HDAC2;ADORA2A;PPARG;PDE3A GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;ADORA2A;HDAC2 GO:0032922| circadian regulation of gene expression NCOA2;HDAC2 GO:0007186| G-protein coupled receptor signaling pathway PDE4A;PPARG;ADORA1;ADORA2A;PDE3A GO:0007165| signal transduction PDE4A;PDE3A;PPARG;ADORA1;ADORA2A GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADORA1;ADORA2A GO:0010033| response to organic substance PPARG;CYP1A2 GO:0031000| response to caffeine PPARG;ADORA2A;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;HDAC2 GO:0048511| rhythmic process PPARG;NCOA2;HDAC2 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC2 7837:[DB07863 DB08341] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0045087| innate immune response PPARG;PTK2B GO:0035902| response to immobilization stress PPARG;PTK2B GO:0071300| cellular response to retinoic acid PPARG;PTK2B GO:0009612| response to mechanical stimulus PTK2B;PPARG GO:0042493| response to drug PPARG;PTK2B GO:0007165| signal transduction PTK2B;PPARG GO:0008285| negative regulation of cell proliferation PTK2B;PPARG 7838:[DB07863 DB00234] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00234|Reboxetine SLC6A2;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0042493| response to drug SLC6A2;PPARG;ABCB1 7839:[DB07863 DB00535] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0009612| response to mechanical stimulus MPO;PPARG 7840:[DB07863 DB11799] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0048469| cell maturation PPARG;POU2F2 GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;POU2F2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;POU2F2 GO:0006355| regulation of transcription, DNA-dependent POU2F2;NCOA2;PPARG;RXRA GO:0042493| response to drug UGT1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent POU2F2;RXRA;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG 7841:[DB07863 DB12329] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 7842:[DB07863 DB01365] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug PPARG;ADRA1A GO:0009409| response to cold ADRB2;ADRB1;ADRB3;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;ADRB2 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0007165| signal transduction ADRA1D;PPARG;ADRB1;ADRA1A;ADRA2A;ADRB3;ADRA2C;ADRB2;ADRA2B;ADRA1B GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRB1;ADRB3;ADRA2A;ADRA1D;PPARG;ADRA1B;ADRB2;ADRA2B;ADRA2C 7843:[DB07863 DB01011] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;ABCC3;NCOA2 GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0042493| response to drug CYP2E1;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP11B2;CYP11B1;PPARG 7844:[DB07863 DB00219] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00219|Oxyphenonium CHRM1 common genes common pathways GO:0007165| signal transduction CHRM1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1 7845:[DB07863 DB13139] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1B1;SLCO1B3 GO:0007165| signal transduction PPARG;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRB2 GO:0009409| response to cold ADRB2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;ADRB2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 7846:[DB07863 DB00313] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes PPARG common pathways GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0030224| monocyte differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;HDAC2;PPARD;PPARA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0042493| response to drug UGT1A1;PPARG;ABAT;SCN11A;CYP1A2;HDAC2 GO:0006355| regulation of transcription, DNA-dependent HDAC2;HDAC9;PPARA;PPARD;PPARG;RXRA;NCOA2 GO:0033189| response to vitamin A PPARG;PPARD GO:0016525| negative regulation of angiogenesis PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;PPARA;PPARD GO:0050872| white fat cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0030522| intracellular receptor mediated signaling pathway PPARA;PPARD;NCOA2 GO:0051289| protein homotetramerization ALDH5A1;RXRA GO:0032922| circadian regulation of gene expression PPARA;HDAC2;NCOA2 GO:0071455| cellular response to hyperoxia PPARG GO:1905563| PPARG GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0071306| cellular response to vitamin E PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;PPARA;PPARD GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;HDAC9;HDAC2;PPARD;PPARA GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0008203| cholesterol metabolic process RXRA;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;RXRA;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARD;CYP3A4;PPARA;PTGS1;UGT2B7;ACADSB;SLC16A1;CYP2C9;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC9;HDAC2;PPARD;PPARA;NCOA2;RXRA;PPARG GO:0007507| heart development HDAC9;PPARA;PPARD;RXRA;PPARG GO:0045165| cell fate commitment PPARG GO:0071300| cellular response to retinoic acid HDAC2;PPARG GO:0009612| response to mechanical stimulus PPARG GO:0009409| response to cold PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;PPARA;HDAC2 GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance CYP1A2;PPARD;UGT1A1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;HDAC2;HDAC9;PPARD GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process HDAC2;PPARA;PPARG;NCOA2 GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;PPARG GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0019395| fatty acid oxidation PPARD;PPARG GO:0001890| placenta development PPARD;RXRA;PPARG GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;RXRA;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;HDAC9 GO:0007566| embryo implantation PPARD;RXRA GO:0019216| regulation of lipid metabolic process PPARA;NCOA2;UGT1A9;RXRA;PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0007165| signal transduction PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0042593| glucose homeostasis PPARG;SLC16A1 7847:[DB07863 DB00476] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00476|Duloxetine SLC6A4;SLC6A2;SLC6A3;CYP1A2;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug SLC6A4;CYP1A2;SLC6A3;SLC6A2;PPARG GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;PPARG;CYP1A2 GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance PPARG;CYP1A2;SLC6A4 7848:[DB07863 DB11963] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PPARG;EGFR GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0007165| signal transduction EGFR;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0033993| response to lipid EGFR;PPARG GO:0042493| response to drug PPARG;UGT1A1;ABCG2;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;RXRA;PPARG GO:0007623| circadian rhythm NCOA2;EGFR GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;NCOA2;PPARG;RXRA 7849:[DB07863 DB00586] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00586|Diclofenac PTGS2;PTGS1;ALOX5;SCN4A;ASIC1;KCNQ2;KCNQ3;PLA2G2A;CYP2C9;CYP2C19;CYP1A2;CYP2C8;UGT1A1;UGT2B7;PTGS1;CYP3A4;CYP1A1;CYP2B6;CYP2C18;CYP2E1;TTR;ALB;ABCC4;ABCB1;ABCC1;SLC22A6;SLC22A8;SLCO1C1;SLC22A11;SLCO1B1;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ABCC4;CYP1A1;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance ABCC4;CYP1A2;PTGS2;UGT1A1;PPARG;CYP1A1 GO:0008217| regulation of blood pressure PPARG;PTGS2;PTGS1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;RXRA;SLCO1C1;NCOA2;ALB GO:0007566| embryo implantation PTGS2;RXRA GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 GO:0007165| signal transduction PPARG;ASIC1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;ABCC1;CYP1A1;PPARG;ABCC4;PTGS2;CYP1A2;CYP2E1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G2A;CYP3A4;PTGS2;CYP1A2;PTGS1;UGT2B7 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG 7850:[DB07863 DB14512] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;PGR;NR3C1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;NCOA2;PPARG;RXRA;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;RXRA;PPARG;NCOA2;PGR GO:0043401| steroid hormone mediated signaling pathway PGR;PPARG;RXRA;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RXRA;PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA;PGR 7851:[DB07863 DB00185] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM1;CHRM3;PPARG GO:0007165| signal transduction CHRM1;PPARG;CHRM3 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 7852:[DB07863 DB00887] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0016032| viral reproduction RXRA;SLC10A1 GO:0042493| response to drug PTGS2;SLC12A5;PPARG GO:0007566| embryo implantation RXRA;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0010033| response to organic substance PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0015721| bile acid and bile salt transport SLCO1A2;RXRA;NCOA2;SLC10A1 GO:0014070| response to organic cyclic compound PPARG;PTGS2 7853:[DB07863 DB09325] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 7854:[DB07863 DB06626] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;PPARG;CYP1A2 GO:0016032| viral reproduction RXRA;KDR GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;NCOA2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 7855:[DB07863 DB00677] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0007584| response to nutrient BCHE;PPARG GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0042493| response to drug BCHE;PPARG 7856:[DB07863 DB00136] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0007165| signal transduction VDR;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;VDR GO:0008285| negative regulation of cell proliferation VDR;PPARG GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;HOXA10;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;HOXA10;VDR GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;VDR GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;HOXA10;VDR GO:0006766| vitamin metabolic process RXRA;CYP24A1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;VDR 7857:[DB07863 DB00776] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 7858:[DB07863 DB14544] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG GO:0042493| response to drug PPARG;ABCB1;HSD11B2;ANXA1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP11B2;CYP11B1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;NR3C1 GO:0045087| innate immune response ANXA1;PPARG GO:0043065| positive regulation of apoptotic process ANXA1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;NR3C1 GO:0008217| regulation of blood pressure PPARG;CYP11B1 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;RXRA GO:0014070| response to organic cyclic compound ANXA1;PPARG GO:0007165| signal transduction NR3C1;PPARG;ANXA1 GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0007186| G-protein coupled receptor signaling pathway ANXA1;PPARG 7859:[DB07863 DB05266] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PDE4D;PDE4A;PDE4B;PDE4C;PDE3A;PPARG GO:0007165| signal transduction PDE4C;PDE4B;PPARG;PDE3A;PDE4A;PDE4D GO:0042493| response to drug PPARG;PDE3A GO:0006629| lipid metabolic process PPARG;PDE3A 7860:[DB07863 DB01427] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0042493| response to drug PDE3A;PPARG GO:0045893| positive regulation of transcription, DNA-dependent TNF;RXRA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;TNF;PPARG GO:0006629| lipid metabolic process PPARG;PDE3A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process TNF;PPARG GO:0006919| activation of caspase activity TNF;PPARG GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG;NCOA2 GO:0010033| response to organic substance TNF;PPARG GO:0045994| positive regulation of translational initiation by iron TNF;RXRA GO:0007186| G-protein coupled receptor signaling pathway PDE4B;PPARG;PDE3A GO:0007165| signal transduction PDE3A;PPARG;PDE4B 7861:[DB07863 DB00349] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0042493| response to drug ABCB1;SLC6A11;PPARG;GABRG3 GO:0007165| signal transduction GABRA5;GABRP;GABRD;PPARG;GABRB3;GABRQ;GABRB1;GABRE;GABRA6 GO:0014070| response to organic cyclic compound SLC6A1;PPARG GO:0010033| response to organic substance PPARG;SLC6A1 7862:[DB07863 DB05229] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;PTGIR GO:0007165| signal transduction PPARG;PTGIR GO:0048662| negative regulation of smooth muscle cell proliferation PTGIR;PPARG 7863:[DB07863 DB01394] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01394|Colchicine TUBB1;TUBB;CYP3A4;CYP2B6;CYP2C8;CYP2E1;ABCB4;SLC22A3;ABCB1;ABCC1 common genes common pathways GO:0019216| regulation of lipid metabolic process ABCB4;RXRA;PPARG;NCOA2 GO:0055088| lipid homeostasis PPARG;ABCB4 GO:0001890| placenta development ABCB4;PPARG;RXRA GO:0010033| response to organic substance ABCB4;PPARG GO:0014070| response to organic cyclic compound PPARG;ABCB4 GO:0006629| lipid metabolic process ABCB4;CYP3A4;PPARG GO:0007623| circadian rhythm NCOA2;ABCB4 GO:0033189| response to vitamin A ABCB4;PPARG GO:0042493| response to drug ABCB1;PPARG;ABCC1;CYP2E1;ABCB4 7864:[DB07863 DB14541] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0045087| innate immune response PPARG;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;NR3C1 GO:0006629| lipid metabolic process PPARG;CYP11B2;CYP11B1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;NR3C1 GO:0043065| positive regulation of apoptotic process PPARG;ANXA1 GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0042493| response to drug PPARG;ABCB1;HSD11B2;ABCG2;ANXA1 GO:0007165| signal transduction NR3C1;ANXA1;PPARG GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ANXA1 GO:0008217| regulation of blood pressure CYP11B1;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1A2 GO:0014070| response to organic cyclic compound PPARG;ANXA1 7865:[DB07863 DB01037] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01037|Selegiline MAOB;MAOA;CYP2B6;CYP3A4;CYP2A6;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;MAOB;PPARG;CYP1A2;CYP2E1 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG 7866:[DB07863 DB01268] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01268|Sunitinib PDGFRB;FLT1;KIT;KDR;FLT4;FLT3;CSF1R;PDGFRA;CYP3A5;CYP3A7;CYP3A4;ABCC4;ABCB1;ABCC2;ABCG2 common genes common pathways GO:0030224| monocyte differentiation PPARG;CSF1R GO:0042493| response to drug ABCC2;ABCG2;ABCB1;PPARG;ABCC4 GO:0016032| viral reproduction RXRA;PDGFRA;KDR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0032526| response to retinoic acid PPARG;PDGFRB;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045087| innate immune response CSF1R;PPARG GO:0043065| positive regulation of apoptotic process PDGFRB;PPARG GO:0014070| response to organic cyclic compound PPARG;PDGFRB;ABCC4 GO:0010033| response to organic substance PPARG;ABCC4 GO:0008285| negative regulation of cell proliferation PPARG;CSF1R GO:0043627| response to estrogen stimulus ABCC2;PPARG;PDGFRB GO:0007186| G-protein coupled receptor signaling pathway PPARG;PDGFRB GO:0007165| signal transduction PPARG;PDGFRB;KIT;CSF1R GO:0033993| response to lipid PDGFRB;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0031100| organ regeneration PPARG;FLT3 7867:[DB07863 DB00363] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00363|Clozapine DRD2;HTR2A;DRD1;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;HRH4;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALY;GSTP1;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2C19;CYP2A6;CYP2C8;FMO3;UGT1A4;CYP2E1;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0007623| circadian rhythm NCOA2;HTR7 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C9;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA;DRD3 GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0042493| response to drug CYP1A2;CYP2E1;HTR2A;DRD1;CYP1A1;PPARG;DRD3;DRD2;ADRA1A;ABCB1;HTR1B;HTR2C GO:1904706| PPARG;GSTP1 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0032869| cellular response to insulin stimulus GSTP1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;DRD3;RXRA;PPARG;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway HTR1E;DRD1;ADRA1B;HTR1D;HRH1;CHRM5;HTR2A;HRH4;ADRA2B;CHRM2;HTR1A;DRD4;ADRA2C;CHRM1;HTR7;CHRM4;HTR1B;ADRA1A;DRD2;HTR6;HTR2C;ADRA2A;CHRM3;DRD3;PPARG GO:0007165| signal transduction HTR3A;CHRM4;HTR7;ADRA1A;DRD2;HTR1B;HTR6;HTR2C;ADRA2A;CHRM3;DRD3;PPARG;HTR1E;DRD1;ADRA1B;HTR1D;HRH1;CHRM5;HRH4;ADRA2B;HTR2A;CHRM2;DRD4;HTR1A;CHRM1;ADRA2C GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0031100| organ regeneration PPARG;GSTP1 GO:0042593| glucose homeostasis ADRA2A;PPARG;ADRA1B GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0008285| negative regulation of cell proliferation CYP1B1;ADRA1A;DRD2;PPARG GO:0010033| response to organic substance PPARG;CYP1A1;CYP1A2 GO:0048511| rhythmic process DRD4;PPARG;NCOA2 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A 7868:[DB07863 DB00928] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00928|Azacitidine DNMT1;CDA common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;RXRA;PPARG;NCOA2 GO:0006351| transcription, DNA-dependent DNMT1;NCOA2;PPARG;RXRA GO:0030308| negative regulation of cell growth PPARG;CDA GO:0051289| protein homotetramerization CDA;RXRA GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;DNMT1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;DNMT1 7869:[DB07863 DB00564] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00564|Carbamazepine SCN5A;CHRNA4;CHRNB2;NR1I2;CYP3A4;CYP2C8;CYP1A2;CYP2C9;CYP2C19;CYP2B6;CYP3A5;CYP3A7;UGT2B7;UGT1A1;ABCB1;RALBP1;ABCC2 common genes common pathways GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;UGT1A1 GO:0007165| signal transduction CHRNB2;PPARG;NR1I2;RALBP1;CHRNA4 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;RXRA GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0042493| response to drug CYP1A2;PPARG;UGT1A1;ABCC2;ABCB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;UGT2B7;CYP2C9;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NR1I2;NCOA2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;RXRA;PPARG GO:0006351| transcription, DNA-dependent RXRA;NR1I2;PPARG;NCOA2 7870:[DB07863 DB13520] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13520|Metergoline SCN2A common genes common pathways 7871:[DB07863 DB09059] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0007507| heart development RXRA;PPARG;OXTR GO:0042493| response to drug OXTR;PPARG GO:0007165| signal transduction OXTR;AVPR1A;AVPR2;AVPR1B;PPARG GO:0032870| cellular response to hormone stimulus AVPR1A;OXTR;AVPR2;AVPR1B;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway AVPR2;PPARG;AVPR1B;AVPR1A;OXTR GO:0010033| response to organic substance PPARG;AVPR1A GO:0014070| response to organic cyclic compound OXTR;PPARG 7872:[DB07863 DB01454] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0007165| signal transduction PPARG;HTR2B;HTR2C;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;PPARG;HTR2B;HTR2C GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0007584| response to nutrient PPARG;SLC6A4 GO:0010033| response to organic substance PPARG;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;PPARG GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0007507| heart development RXRA;PPARG;HTR2B GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug PPARG;SLC6A2;SLC6A3;HTR2C;HTR2B;HTR2A;SLC6A4 7873:[DB07863 DB00204] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway KCNK2;PPARG GO:0051289| protein homotetramerization KCNJ12;RXRA GO:0009612| response to mechanical stimulus KCNK2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7874:[DB07863 DB00813] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00813|Fentanyl OPRM1;OPRD1;OPRK1;ABCB1;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;OPRK1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 7875:[DB07863 DB00914] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0007165| signal transduction PRKAA1;PPARG GO:0042593| glucose homeostasis PRKAA1;PPARG GO:0031000| response to caffeine PPARG;PRKAA1 GO:0048511| rhythmic process NCOA2;PPARG;PRKAA1 GO:0019395| fatty acid oxidation PPARG;PRKAA1 GO:0071380| cellular response to prostaglandin E stimulus PPARG;PRKAA1 GO:0006351| transcription, DNA-dependent PRKAA1;NCOA2;RXRA;PPARG GO:0008203| cholesterol metabolic process PRKAA1;RXRA GO:0006629| lipid metabolic process PRKAA1;CYP2D6;PPARG GO:0007507| heart development KCNJ8;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent PRKAA1;NCOA2;PPARG;RXRA GO:0042752| regulation of circadian rhythm PRKAA1;PPARG 7876:[DB07863 DB00469] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0042493| response to drug PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS1;PTGS2;PPARG;CYP2C9 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2 GO:0007566| embryo implantation PTGS2;RXRA 7877:[DB07863 DB00454] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00454|Meperidine OPRK1;GRIN1;GRIN2B;GRIN2A;GRIN2C;GRIN2D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;OPRM1;SLC6A3;SLC6A2;SLC6A4;CES1;CYP3A4;CYP2C19;CYP2B6;CYP2D6;CYP1A2;ALB;ORM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM3;PPARG;CHRM4;OPRK1;OPRM1;CHRM5;CHRM2;CHRM1 GO:0007165| signal transduction PPARG;CHRM3;OPRK1;CHRM4;CHRM2;CHRM1;OPRM1;CHRM5 GO:0014070| response to organic cyclic compound PPARG;SLC6A3;CYP1A2 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0007584| response to nutrient SLC6A4;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance PPARG;SLC6A4;CYP1A2 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PPARG;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;GRIN2A;GRIN1 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2D6 GO:0042493| response to drug CYP1A2;SLC6A4;GRIN2A;PPARG;SLC6A2;SLC6A3 7878:[DB07863 DB00489] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;NCOA2;RXRA;PPARG GO:0009409| response to cold PPARG;ADRB1;ADRB2 GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0007165| signal transduction ADRB2;PPARG;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;PPARG;ADRB2 7879:[DB07863 DB01015] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4;PTGS1 GO:1904706| PPARG;GSTP1 GO:0032869| cellular response to insulin stimulus GSTP1;PPARG GO:0019216| regulation of lipid metabolic process UGT1A9;NCOA2;PPARG;RXRA GO:0031100| organ regeneration GSTP1;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB;ABCB11 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 7880:[DB07863 DB00321] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00321|Amitriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;OPRD1;OPRK1;NTRK1;NTRK2;ADRA1A;ADRA1D;ADRA2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCNQ2;KCNA1;KCND2;KCND3;HRH2;HRH4;SIGMAR1;HTR2C;ADRA1B;HTR7;HTR1D;OPRM1;HTR1B;HTR6;KCNQ3;ADRB1;ADRB2;ADRB3;CYP2D6;CYP1A2;CYP2C19;CYP2C9;CYP3A4;CYP3A5;CYP2B6;CYP2C8;CYP2E1;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0007584| response to nutrient SLC6A4;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;NTRK1;PPARG;ADRA1A GO:0010033| response to organic substance CYP1A2;SLC6A4;PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C;HTR2A GO:0045475| locomotor rhythm NCOA2;KCND2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1;CYP1A2 GO:0007165| signal transduction HTR1A;CHRM1;HRH4;ADRB2;HTR2A;HRH2;CHRM2;CHRM5;OPRM1;OPRD1;HTR1D;HRH1;ADRA1B;PPARG;ADRA1D;CHRM3;HTR6;HTR2C;ADRA2A;ADRB3;OPRK1;ADRA1A;HTR1B;ADRB1;CHRM4;HTR7 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042593| glucose homeostasis ADRA1B;PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRA1D;CHRM3;ADRA2A;HTR6;HTR2C;OPRK1;ADRB3;ADRA1A;ADRB1;HTR1B;CHRM4;HTR7;CHRM1;HTR1A;HRH2;CHRM2;ADRB2;HRH4;HTR2A;CHRM5;OPRM1;HTR1D;HRH1;OPRD1;ADRA1B GO:0016032| viral reproduction RXRA;HTR2A GO:0042493| response to drug HTR2C;HTR1B;ABCB1;ADRA1A;NTRK1;PPARG;SLC6A2;UGT1A1;SLC6A4;HTR2A;CYP2E1;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4;CYP1A2 GO:0042594| response to starvation UGT1A1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;ADRB2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0009409| response to cold ADRB2;ADRB1;ADRB3;PPARG GO:0007623| circadian rhythm SLC6A4;NCOA2;NTRK2;NTRK1;HTR7 7881:[DB07863 DB02261] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process GM2A;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PTAFR;PPARG GO:0007165| signal transduction PPARG;PTAFR GO:0007186| G-protein coupled receptor signaling pathway PPARG;PTAFR 7882:[DB07863 DB00248] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C;HTR2A GO:0048511| rhythmic process DRD4;PPARG;NCOA2 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0007186| G-protein coupled receptor signaling pathway HTR1D;ADRB2;ADRA2B;HTR2A;DRD4;HTR1A;ADRA2C;DRD5;DRD1;ADRA1B;ADRA1D;DRD3;PPARG;HTR7;ADRA1A;DRD2;HTR1B;ADRB1;HTR2B;HTR2C;ADRA2A GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;DRD3 GO:0042593| glucose homeostasis PPARG;ADRA2A;ADRA1B GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007165| signal transduction HTR2C;HTR2B;ADRA2A;DRD2;ADRA1A;HTR1B;ADRB1;HTR7;PPARG;DRD3;ADRA1D;ADRA1B;DRD1;DRD5;DRD4;HTR1A;ADRA2C;ADRA2B;ADRB2;HTR2A;HTR1D GO:0042493| response to drug ADRA1A;DRD2;ABCB1;HTR1B;HTR2B;HTR2C;DRD3;PPARG;DRD1;HTR2A GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0016032| viral reproduction RXRA;HTR2A GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0007623| circadian rhythm NCOA2;HTR7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;DRD2;NCOA2;PPARG;DRD3;RXRA GO:0009409| response to cold PPARG;ADRB1;ADRB2 GO:0007507| heart development RXRA;PPARG;HTR2B GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG 7883:[DB07863 DB00209] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1 GO:0007165| signal transduction PPARG;CHRM1 7884:[DB07863 DB00359] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 GO:0042493| response to drug PPARG;CYP2E1 7885:[DB07863 DB00761] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0042493| response to drug SLC12A5;PPARG 7886:[DB07863 DB01028] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;MT-ND1;CYP2E1;CYP1A2;GABRG3 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;PPARG;CYP2D6 GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG;MT-ND1 GO:0007165| signal transduction GABRE;GABRB1;GABRQ;GABRA6;ATP2C1;GABRB3;GABRA5;PPARG;GABRD;GABRP;GRIA1 7887:[DB07863 DB05104] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05104|Asimadoline OPRK1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG GO:0007165| signal transduction OPRK1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG 7888:[DB07863 DB09071] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0007623| circadian rhythm MTNR1A;MTNR1B;NCOA2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG GO:0042493| response to drug CYP1A2;PPARG GO:0007186| G-protein coupled receptor signaling pathway MTNR1B;PPARG;MTNR1A GO:0007165| signal transduction MTNR1B;PPARG;MTNR1A GO:0042593| glucose homeostasis PPARG;MTNR1B GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG 7889:[DB07863 DB00900] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes common pathways GO:0042493| response to drug PPARG;PNP GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA 7890:[DB07863 DB00977] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0007165| signal transduction ESR1;NR1I2;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2;UGT1A1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG;NCOA2 GO:0010033| response to organic substance UGT1A1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus ABCC2;PPARG;ESR1 GO:0015721| bile acid and bile salt transport SLC10A1;NCOA2;RXRA;ABCB11 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;PPARG;NR1I2;RXRA GO:0006351| transcription, DNA-dependent ESR1;NCOA2;NR1I2;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1I2;PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1I2;RXRA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0016032| viral reproduction RXRA;SLC10A1 GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;PPARG;NR1I2;RXRA GO:0042493| response to drug PPARG;UGT1A1;ABCC2;ABCB1 7891:[DB07863 DB00246] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;DRD3 GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;DRD2;HTR1B;CHRM4;HTR7;HTR6;HTR2C;ADRA2A;CHRM3;PPARG;DRD3;HTR1E;DRD5;ADRA1B;DRD1;CHRM5;HTR1D;HRH1;DRD4;HTR1A;CHRM1;ADRA2C;ADRA2B;HTR2A;CHRM2 GO:0007165| signal transduction DRD5;HTR1E;DRD1;ADRA1B;HTR1D;HRH1;CHRM5;CHRM2;ADRA2B;HTR2A;CHRM1;ADRA2C;DRD4;HTR1A;CHRM4;HTR3A;HTR7;ADRA1A;DRD2;HTR1B;ADRA2A;HTR6;HTR2C;CHRM3;DRD3;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis ADRA2A;PPARG;ADRA1B GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0048511| rhythmic process DRD4;PPARG;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C;HTR2A GO:0007623| circadian rhythm HTR7;NCOA2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP1A2;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG;DRD2 GO:0042493| response to drug ADRA1A;DRD2;HTR1B;HTR2C;DRD3;PPARG;DRD1;CYP1A2;HTR2A GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 7892:[DB07863 DB00907] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0042493| response to drug SCN11A;SLC6A4;BCHE;SLC6A2;PPARG;SLC6A3 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0010033| response to organic substance SLC6A4;PPARG GO:0008285| negative regulation of cell proliferation BCHE;PPARG GO:0007584| response to nutrient SLC6A4;PPARG;BCHE GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0007165| signal transduction CHRM1;CHRM2;PPARG GO:0007186| G-protein coupled receptor signaling pathway CHRM1;CHRM2;PPARG 7893:[DB07863 DB00605] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG;NCOA2 GO:0010033| response to organic substance PPARD;PTGS2;AKR1B1;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0001890| placenta development RXRA;PPARG;PPARD GO:0019395| fatty acid oxidation PPARG;PPARD GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;PPARG GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0007566| embryo implantation RXRA;PTGS2;PPARD GO:0007165| signal transduction PPARG;PTGDR2 GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;PPARD GO:0042493| response to drug PTGS2;PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;PPARD GO:0033189| response to vitamin A PPARG;CYP1A1;PPARD GO:0030522| intracellular receptor mediated signaling pathway NCOA2;PPARD GO:0016032| viral reproduction MAPK3;RXRA GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;MAPK3;PPARD GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;PPARD GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0008203| cholesterol metabolic process RXRA;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG;RXRA GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0007507| heart development PPARD;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;PPARD GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0006629| lipid metabolic process PPARD;PTGS2;PTGS1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;MAPK3 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG 7894:[DB07863 DB05838] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05838|OPC-51803 AVPR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;AVPR2 GO:0032870| cellular response to hormone stimulus NCOA2;AVPR2 GO:0007165| signal transduction AVPR2;PPARG 7895:[DB07863 DB01355] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;PTGS1 GO:0042493| response to drug PPARG;CYP2E1 GO:0007165| signal transduction GABRA5;PPARG;GABRA6;CHRNA4;GRIA2;CHRNA7 GO:0008217| regulation of blood pressure PTGS1;PPARG 7896:[DB07863 DB00651] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PDE4A;PDE4D;ADORA2A;PPARG;ADORA1;PDE7A;PDE4B;PDE4C;PDE7B GO:0007165| signal transduction PDE7B;PDE4B;PDE4C;PDE7A;ADORA1;PPARG;ADORA2A;PDE4D;PDE4A GO:0031000| response to caffeine PPARG;ADORA2A GO:0008285| negative regulation of cell proliferation PPARG;ADORA1;ADORA2A GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ADORA2A;RXRA GO:0042493| response to drug ADORA2A;PPARG 7897:[DB07863 DB06230] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0006629| lipid metabolic process PPARG;UGT2B7 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRD1;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;PPARG;OPRK1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 7898:[DB07863 DB00457] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A1;PPARG;ABCG2;ADRA1A;ABCB1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0010033| response to organic substance PPARG;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADRA1D;ADRA2A;ADRA1A;ADRA2B;ADRA1B GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0042593| glucose homeostasis ADRA2A;PPARG;ADRA1B GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007165| signal transduction ADRA1B;ADRA2B;ADRA2A;ADRA1A;PPARG;ADRA1D 7899:[DB07863 DB09048] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;TACR1 GO:0008217| regulation of blood pressure TACR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway TACR1;PPARG GO:0007165| signal transduction TACR1;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4 7900:[DB07863 DB09216] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0007566| embryo implantation RXRA;PTGS2 GO:0042493| response to drug PPARG;PTGS2 GO:0006629| lipid metabolic process PPARG;PTGS1;CYP3A4;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG 7901:[DB07863 DB00820] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways GO:0007165| signal transduction PPARG;PDE5A;PDE11A GO:0007186| G-protein coupled receptor signaling pathway PDE11A;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7902:[DB07863 DB08889] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways GO:0016032| viral reproduction PSMB10;PSMB1;PSMB5;PSMB9;PSMB2;RXRA;PSMB8 GO:0042493| response to drug PPARG;ABCB1 GO:0014070| response to organic cyclic compound PSMB2;PPARG 7903:[DB07863 DB06728] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB 7904:[DB07863 DB00687] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0007165| signal transduction NR3C2;PPARG;AR;NR3C1 GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;AR;NR3C1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;NR3C1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;AR GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;NR3C2;NR3C1;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;NR3C2;NR3C1;AR GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0001701| in utero embryonic development RXRA;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;NR3C1;NR3C2;RXRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AR;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent NR3C2;RXRA;PPARG;NCOA2;AR;NR3C1 7905:[DB07863 DB01544] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0042493| response to drug PPARG;UGT1A1;TSPO;CYP2E1 GO:0043065| positive regulation of apoptotic process PPARG;TSPO GO:0006629| lipid metabolic process CYP3A4;UGT2B7;PPARG;CYP2C9 GO:0042594| response to starvation PPARG;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction GABRA5;PPARG;GABRA6;TSPO;GABRB3 7906:[DB07863 DB04743] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04743|Nimesulide PTGS2;PLA2G2E;LTF;CYP3A4 common genes common pathways GO:0007566| embryo implantation PTGS2;RXRA GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;LTF GO:0006629| lipid metabolic process PLA2G2E;PPARG;CYP3A4;PTGS2 GO:0045087| innate immune response PPARG;LTF GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0042493| response to drug PPARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent LTF;RXRA;PPARG;NCOA2 7907:[DB07863 DB09477] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways GO:0008217| regulation of blood pressure ACE;PPARG GO:0007165| signal transduction PPARG;BDKRB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;BDKRB1 GO:0009612| response to mechanical stimulus PPARG;BDKRB1 GO:0030308| negative regulation of cell growth PPARG;BDKRB1 7908:[DB07863 DB00571] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0007165| signal transduction PPARG;ADRB3;ADRB1;HTR1B;HTR1A;ADRB2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway HTR1B;ADRB1;ADRB3;PPARG;HTR1A;ADRB2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug CYP1A2;ABCB1;HTR1B;CYP1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0009409| response to cold ADRB3;ADRB1;PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;RXRA;NCOA2 7909:[DB07863 DB00806] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ADORA2A;RXRA;NCOA2 GO:0042493| response to drug PPARG;ADORA2A;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PDE4A;PDE4B;ADORA1;PPARG;ADORA2A GO:0007165| signal transduction PDE4A;PDE4B;ADORA2A;ADORA1;PPARG;PDE5A GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0031000| response to caffeine PPARG;ADORA2A GO:0008285| negative regulation of cell proliferation ADORA2A;ADORA1;PPARG GO:0010033| response to organic substance CYP1A2;PPARG 7910:[DB07863 DB14146] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRM1;OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;OPRK1;PPARG GO:0042493| response to drug ABCB1;PPARG 7911:[DB07863 DB00808] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00808|Indapamide SLC12A3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 7912:[DB07863 DB00159] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes PPARG common pathways GO:0042493| response to drug SLC8A1;PTGS2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;FADS1;NCOA2;PPARA;PPARD GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;PPARA;PPARD GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0030224| monocyte differentiation PPARG GO:0061614| PPARG GO:0051289| protein homotetramerization RXRA;TRPV1 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;PPARA;PPARD GO:0032922| circadian regulation of gene expression PPARA;NCOA2 GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;PPARA;PPARD GO:0050872| white fat cell differentiation PPARG GO:0033189| response to vitamin A PPARG;PPARD GO:0016525| negative regulation of angiogenesis PPARG GO:1904706| PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;PPARD GO:0008203| cholesterol metabolic process PPARD;RXRA GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid RXRA;PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARA;RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;PPARD;PPARA GO:0043065| positive regulation of apoptotic process PTGS2;PPARG;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;PPARA GO:0071300| cellular response to retinoic acid PPARG GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0007507| heart development PPARD;PPARA;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;TRPV1;PPARD;PPARA GO:0045087| innate immune response PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process TRPV1;ACSL4;ACSL3;PPARG;FADS1;PTGS1;PTGS2;PPARD;PPARA GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG;SLC8A1 GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound PPARG;ACSL3;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARD;PPARG;RXRA GO:0019395| fatty acid oxidation PPARD;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient ACSL4;PPARG;ACSL3;SLC8A1 GO:0048511| rhythmic process PPARG;NCOA2;PPARA GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance PPARD;PTGS2;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PTGS2;FABP7;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2;PPARD GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;FFAR1 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;FADS1;PPARG;PPARA GO:0007566| embryo implantation RXRA;PPARD;PTGS2 GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0042593| glucose homeostasis FFAR1;PPARG GO:0031100| organ regeneration PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0007165| signal transduction PPARG;FFAR1 GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD 7913:[DB07863 DB00951] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00951|Isoniazid katG;CYP2C8;CYP1A2;CYP3A4;CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2D6;CYP2C19;NAT2;CYP2A6;CYP2C8;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;PPARG;CYP2D6 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042493| response to drug PPARG;CYP1A2;CYP2E1 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB 7914:[DB07863 DB00988] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0007566| embryo implantation RXRA;SOD1 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;DRD3;RXRA GO:0007186| G-protein coupled receptor signaling pathway DRD2;HTR7;PPARG;DRD3;DRD5;DRD1;HTR1A;DRD4 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0042593| glucose homeostasis DBH;PPARG GO:0007165| signal transduction DRD3;PPARG;HTR7;HTR3A;DRD2;HTR1A;DRD4;DRD1;HTR3B;DRD5 GO:0014070| response to organic cyclic compound PPARG;COMT;SLC6A3 GO:0060965| negative regulation of gene silencing by miRNA POU5F1;PPARG GO:0001890| placenta development SOD1;RXRA;PPARG GO:0008217| regulation of blood pressure PPARG;SOD1 GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0010033| response to organic substance PPARG;SLC6A4;SOD1 GO:0048511| rhythmic process DRD4;PPARG;NCOA2 GO:0007584| response to nutrient PPARG;SLC6A4 GO:0043627| response to estrogen stimulus PPARG;COMT GO:0007623| circadian rhythm SLC6A4;NCOA2;HTR7 GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;POU5F1 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter POU5F1;DRD2;NCOA2;PPARG;RXRA;DRD3 GO:0043065| positive regulation of apoptotic process SOD1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;DRD3;PPARG;POU5F1 GO:0006355| regulation of transcription, DNA-dependent POU5F1;PPARG;RXRA;NCOA2 GO:0042493| response to drug SOD1;SLC6A4;DRD1;PPARG;DRD3;COMT;MAOB;SLC6A2;SLC6A3;DRD2 GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0042752| regulation of circadian rhythm DRD4;PPARG 7915:[DB07863 DB00317] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound EGFR;CYP1A1;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0010033| response to organic substance PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0033993| response to lipid PPARG;EGFR GO:0007165| signal transduction EGFR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent EGFR;RXRA;PPARG GO:0042493| response to drug ABCB1;ABCG2;PPARG;CYP1A1 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;PPARG;RXRA GO:0007623| circadian rhythm NCOA2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;EGFR GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG;CYP2C9 GO:0035902| response to immobilization stress CYP1A1;PPARG 7916:[DB07863 DB01184] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;RXRA;DRD3;PPARG GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0042493| response to drug CYP1A2;ABCB1;DRD2;DRD3;PPARG GO:0007165| signal transduction DRD2;PPARG;DRD3 GO:0007186| G-protein coupled receptor signaling pathway DRD2;PPARG;DRD3 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;DRD3;PPARG GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG 7917:[DB07863 DB11915] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4 7918:[DB07863 DB01579] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;PPARG;ADRA1A GO:0007165| signal transduction PPARG;ADRA1A;ADRA1B GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0042493| response to drug ADRA1A;SLC6A2;PPARG 7919:[DB07863 DB06663] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0042594| response to starvation SSTR3;SSTR2;PPARG;SSTR1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0008285| negative regulation of cell proliferation PPARG;SSTR1;SSTR2;SSTR5;SSTR3 GO:0007584| response to nutrient SSTR2;PPARG;SSTR1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;SSTR1;SSTR2;SSTR5;SSTR3 GO:0042593| glucose homeostasis PPARG;SSTR5 GO:0007165| signal transduction SSTR2;SSTR1;PPARG;SSTR3;SSTR5 7920:[DB07863 DB00082] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0007584| response to nutrient PPARG;BCHE GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0019216| regulation of lipid metabolic process CYP4A11;NCOA2;RXRA;PPARG GO:0032870| cellular response to hormone stimulus GHR;NCOA2 GO:0042493| response to drug BCHE;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7921:[DB07863 DB00870] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0007566| embryo implantation PTGS2;RXRA GO:0007584| response to nutrient UGT1A1;PPARG GO:0008217| regulation of blood pressure PTGS2;PTGS1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;PTGS2;PTGS1;UGT2B7 GO:0042594| response to starvation UGT1A1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0042493| response to drug UGT1A1;PPARG;PTGS2 7922:[DB07863 DB00899] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007165| signal transduction PPARG;OPRK1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRM1;OPRD1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG 7923:[DB07863 DB01103] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways GO:0007165| signal transduction PLCL1;PPARG GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process PLA2G6;PPARG;PLA2G4A;PLCL1;CYP3A4 7924:[DB07863 DB13165] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0048511| rhythmic process ROCK2;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ROCK1;ROCK2;PPARG GO:0007165| signal transduction ROCK1;PPARG GO:0016525| negative regulation of angiogenesis ROCK1;ROCK2;PPARG GO:0042752| regulation of circadian rhythm PPARG;ROCK2 7925:[DB07863 DB00686] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent FGF2;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF4;RXRA;PPARG;NCOA2;FGF1;FGF2 GO:0043537| negative regulation of blood vessel endothelial cell migration FGF2;PPARG GO:0007165| signal transduction FGF1;FGF2;PPARG;FGF4 7926:[DB07863 DB00091] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00091|Ciclosporin CAMLG;PPP3R2;PPIA;PPIF;CYP3A7;CYP3A5;CYP3A4;CYP2C19;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCC3;ABCB11;ABCC1;SLCO1A2;SLC10A2;SLC10A1;SLC22A6;ABCC10;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG;CYP2C9 GO:0042493| response to drug ABCG2;ABCC2;ABCB1;PPARG;ABCC1 GO:0016032| viral reproduction PPIA;RXRA;CAMLG;SLC10A1 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2 GO:0007165| signal transduction PPARG;CAMLG GO:0015721| bile acid and bile salt transport SLCO1B3;ABCB11;SLCO1B1;SLCO1A2;SLC10A1;SLC10A2;RXRA;NCOA2;ABCC3 GO:0043627| response to estrogen stimulus PPARG;ABCC2 7927:[DB07863 DB11156] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;CYP4A11 GO:0007186| G-protein coupled receptor signaling pathway CHRM1;PPARG;GPR35 GO:0007165| signal transduction PPARG;GPR35;CHRM1 7928:[DB07863 DB05131] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05131|TTP889 F9 common genes common pathways 7929:[DB07863 DB09546] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;PPARG 7930:[DB07863 DB08496] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08496|(R)-warfarin CYP2C8;CYP2C9;CYP2C18;CYP2C19;CYP1A2;CYP1A1;CYP3A4;ALB common genes common pathways GO:0033189| response to vitamin A CYP1A1;PPARG GO:0042493| response to drug PPARG;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2C9 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 7931:[DB07863 DB08879] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08879|Belimumab TNFSF13B common genes common pathways GO:0007165| signal transduction TNFSF13B;PPARG 7932:[DB07863 DB01325] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010033| response to organic substance CA2;PPARG 7933:[DB07863 DB01353] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GABRA5;PPARG;GABRA6;CHRNA4;GRIA2;CHRNA7 7934:[DB07863 DB00230] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 7935:[DB07863 DB00588] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway NR3C2;PGR;RXRA;PPARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;PGR;NR3C2;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PLA2G4A;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;PGR;NR3C1 GO:0042493| response to drug PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;PGR;NR3C2;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR3C2;PGR;NR3C1 GO:0007165| signal transduction NR3C2;PGR;PPARG;NR3C1 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1B1 7936:[DB07863 DB08828] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0001701| in utero embryonic development RXRA;SMO GO:0045893| positive regulation of transcription, DNA-dependent SMO;PPARG;RXRA GO:0042493| response to drug ABCB1;ABCG2;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter SMO;PPARG;RXRA;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;SMO GO:0045892| negative regulation of transcription, DNA-dependent SMO;NCOA2;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0007165| signal transduction SMO;PPARG GO:0007186| G-protein coupled receptor signaling pathway SMO;PPARG 7937:[DB07863 DB07449] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0045087| innate immune response PPARG;PADI4 GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PADI4;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;PADI4 7938:[DB07863 DB00819] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010033| response to organic substance CA2;PPARG GO:0042493| response to drug AQP1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0071300| cellular response to retinoic acid PPARG;AQP1 7939:[DB07863 DB00284] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 7940:[DB07863 DB01067] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes PPARG common pathways GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0030224| monocyte differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA GO:0042493| response to drug PPARG;UGT1A1;ABCC8 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2 GO:0033189| response to vitamin A PPARG GO:0016525| negative regulation of angiogenesis ABCC8;PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG GO:0050872| white fat cell differentiation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2 GO:0045087| innate immune response PPARG GO:0007507| heart development RXRA;PPARG GO:0045165| cell fate commitment PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG GO:0009409| response to cold PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0008217| regulation of blood pressure PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process NCOA2;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development RXRA;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG GO:0015721| bile acid and bile salt transport ABCB11;RXRA;NCOA2 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction ABCC8;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042593| glucose homeostasis PPARG 7941:[DB07863 DB01159] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0007165| signal transduction GABRA5;RHO;GABRP;PPARG;GABRD;ATP2C1;GNG2;NPSR1;GABRB3;GABRB1;GABRQ;GABRE;GABRA6 GO:0007186| G-protein coupled receptor signaling pathway NPSR1;GNG2;PPARG;RHO GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0071380| cellular response to prostaglandin E stimulus GNG2;PPARG GO:0014070| response to organic cyclic compound PPARG;MT-ND1 GO:0043065| positive regulation of apoptotic process PPARG;KCNMA1;GRIN2A GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG GO:0042493| response to drug CYP2E1;GRIN2A;GABRG3;MT-ND1;PPARG;KCNK3 7942:[DB07863 DB01013] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent RXRA;PPARG;NCOA2;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;RXRA;PPARG;NCOA2 GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;NR3C1 GO:0042493| response to drug PPARG;CYP1A1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR3C1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;NCOA2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007165| signal transduction PPARG;NR3C1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0010033| response to organic substance PPARG;CYP1A1 7943:[DB07863 DB04868] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;KIT GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;ABL1 GO:0042493| response to drug ABCG2;ABCB1;PPARG;UGT1A1 GO:0045087| innate immune response PPARG;ABL1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG;CYP2C9 GO:0042594| response to starvation UGT1A1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;ABL1 GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;PPARG;RXRA GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007165| signal transduction KIT;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 7944:[DB07863 DB14066] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PPARG 7945:[DB07863 DB00703] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0042493| response to drug PPARG;CYP2E1 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010033| response to organic substance PPARG;CA2 7946:[DB07863 DB01069] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01069|Promethazine HRH1;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;HTR2A;CALM1;HRH2;CYP2D6;CYP2B6;CYP2C9;ABCB1 common genes common pathways GO:0007165| signal transduction HRH1;CHRM5;CHRM2;HRH2;HTR2A;CHRM1;CHRM3;PPARG;CHRM4;DRD2;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway CALM1;HRH2;CHRM2;HTR2A;CHRM1;HRH1;CHRM5;CHRM4;ADRA1A;DRD2;PPARG;CHRM3 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;RXRA;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6 GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0042493| response to drug HTR2A;ABCB1;ADRA1A;DRD2;PPARG 7947:[DB07863 DB00203] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00203|Sildenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2D6;CYP1A1;CYP2E1;ABCC4;ABCC5;ABCC10;SLCO1B1;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1B1 GO:0010033| response to organic substance CYP1A1;PPARG;ABCC4 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;ABCC4 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction PDE5A;PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0042493| response to drug ABCB1;PPARG;CYP1A1;ABCC4;CYP2E1 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A1 7948:[DB07863 DB06470] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 7949:[DB07863 DB01340] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure ACE;PPARG GO:0042493| response to drug PPARG;ABCB1 7950:[DB07863 DB00009] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm NCOA2;SERPINE1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;NCOA2;PPARG;RXRA GO:0045087| innate immune response FGA;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PLG GO:0043388| positive regulation of DNA binding PPARG;PLAUR GO:0007165| signal transduction PPARG;FGA;PLAUR 7951:[DB07863 DB01628] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01628|Etoricoxib PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;PTGS2;CYP1A2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;PTGS2;CYP1A2;CYP2C9;PPARG;CYP2D6 GO:0014070| response to organic cyclic compound PPARG;CYP1A2;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0007566| embryo implantation RXRA;PTGS2 7952:[DB07863 DB01001] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;RXRA;NCOA2 GO:0009409| response to cold ADRB2;PPARG;ADRB1;ADRB3 GO:0007165| signal transduction ADRB2;PPARG;ADRB3;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG;ADRB3;ADRB1 7953:[DB07863 DB01002] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0042493| response to drug PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 7954:[DB07863 DB04842] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;PPARG;DRD2 GO:0007165| signal transduction HTR2A;PPARG;DRD2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug DRD2;PPARG;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0016032| viral reproduction RXRA;HTR2A 7955:[DB07863 DB01392] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0007165| signal transduction HTR1D;HTR2A;ADRA2B;HTR1A;ADRA2C;DRD3;PPARG;HTR1B;DRD2;HTR2C;HTR2B;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0019216| regulation of lipid metabolic process DRD3;RXRA;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;HTR2B;HTR2C;DRD2;HTR1B;PPARG;DRD3;ADRA2C;HTR1A;ADRA2B;HTR2A;HTR1D GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD3 GO:0007507| heart development HTR2B;RXRA;PPARG;KCNJ8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA;DRD3 GO:0016032| viral reproduction RXRA;HTR2A GO:0051289| protein homotetramerization RXRA;KCNJ12 GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0042493| response to drug PPARG;DRD3;HTR2B;HTR2C;DRD2;HTR1B;KCNJ11;HTR2A 7956:[DB07863 DB01809] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;RET GO:0042493| response to drug PPARG;RET GO:0016032| viral reproduction RXRA;HCK GO:0071300| cellular response to retinoic acid PPARG;RET GO:0045087| innate immune response HCK;PPARG GO:0006919| activation of caspase activity PPARG;RET GO:0007165| signal transduction RET;PPARG 7957:[DB07863 DB00833] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ABCB11;NCOA2;RXRA GO:0009612| response to mechanical stimulus MPO;PPARG 7958:[DB07863 DB00591] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;ANXA1 GO:0031100| organ regeneration ANXA3;PPARG GO:0007165| signal transduction ANXA4;PPARG;ANXA1;NR3C1;ANXA5 GO:0014070| response to organic cyclic compound PPARG;ANXA1 GO:0030855| epithelial cell differentiation ANXA4;PPARG GO:0010033| response to organic substance PPARG;ANXA5 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;ANXA4 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C1 GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;NR3C1 GO:0043065| positive regulation of apoptotic process ANXA1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;RXRA;PPARG;NCOA2 GO:0045087| innate immune response ANXA1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;NR3C1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug ANXA1;PPARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ANXA3 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG 7959:[DB07863 DB01142] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01142|Doxepin HRH1;HRH2;SLC6A2;SLC6A4;HTR2A;HTR2B;HTR2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR1A;ADRA2A;ADRA2B;ADRA2C;DRD2;HTR6;HRH4;KCNH2;CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;ORM1;ABCB1 common genes common pathways GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;PPARG;CYP2D6 GO:0007507| heart development HTR2B;PPARG;RXRA GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;DRD2 GO:0007623| circadian rhythm SLC6A4;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0042493| response to drug HTR2B;HTR2C;ADRA1A;DRD2;ABCB1;PPARG;SLC6A2;SLC6A4;HTR2A;CYP1A2 GO:0007165| signal transduction CHRM2;HRH2;ADRA2B;HRH4;HTR2A;CHRM1;ADRA2C;HTR1A;HRH1;CHRM5;ADRA1B;PPARG;CHRM3;ADRA1D;ADRA2A;HTR2C;HTR6;HTR2B;CHRM4;DRD2;ADRA1A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis ADRA1B;PPARG;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;HRH4;ADRA2B;HRH2;CHRM2;HTR1A;ADRA2C;CHRM1;HRH1;CHRM5;ADRA1B;PPARG;CHRM3;ADRA1D;HTR6;HTR2B;HTR2C;ADRA2A;CHRM4;ADRA1A;DRD2 GO:0010033| response to organic substance PPARG;SLC6A4;CYP1A2 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0007584| response to nutrient SLC6A4;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2 7960:[DB07863 DB05271] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0042493| response to drug DRD1;DRD3;PPARG;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;DRD3;RXRA;PPARG GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0048511| rhythmic process PPARG;NCOA2;DRD4 GO:0007165| signal transduction DRD3;PPARG;DRD2;ADRA2B;HTR1A;DRD4;DRD1;DRD5 GO:0019216| regulation of lipid metabolic process DRD3;RXRA;PPARG;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway DRD1;DRD5;DRD4;HTR1A;ADRA2B;DRD2;PPARG;DRD3 7961:[DB07863 DB12483] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0007186| G-protein coupled receptor signaling pathway PPARG;PIK3CA GO:0007165| signal transduction PPARG;PIK3CD GO:0042493| response to drug PPARG;ABCG2;ABCB1 GO:0045087| innate immune response PIK3CA;PIK3CD;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 7962:[DB07863 DB11693] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;PPP3R1 GO:0007507| heart development PPARG;RXRA;PPP3R1 7963:[DB07863 DB05152] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05152|NGX267 CHRM1 common genes common pathways GO:0007165| signal transduction PPARG;CHRM1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1 7964:[DB07863 DB00432] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0014070| response to organic cyclic compound TYMS;PPARG GO:0007623| circadian rhythm TYMS;NCOA2 GO:0033189| response to vitamin A PPARG;TYMS GO:0051289| protein homotetramerization TK1;RXRA GO:0042493| response to drug PPARG;TYMS 7965:[DB07863 DB00731] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes PPARG common pathways GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:1905461| PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0042593| glucose homeostasis SLC16A1;PPARG GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction ABCC8;PPARG GO:0014070| response to organic cyclic compound PPARG;ABCC4 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0001890| placenta development RXRA;PPARG GO:0019395| fatty acid oxidation PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0045600| positive regulation of fat cell differentiation PPARG GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0031000| response to caffeine PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010033| response to organic substance PPARG;ABCC4 GO:0008285| negative regulation of cell proliferation PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process NCOA2;PPARG GO:0007584| response to nutrient PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0032526| response to retinoic acid RXRA;PPARG GO:0048469| cell maturation PPARG GO:0009612| response to mechanical stimulus PPARG GO:0009409| response to cold PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA GO:0043065| positive regulation of apoptotic process PPARG GO:0035902| response to immobilization stress PPARG GO:0042953| lipoprotein transport PPARG GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;CYP3A4;SLC16A1;PTGS1 GO:0045165| cell fate commitment PPARG GO:0007507| heart development RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA GO:0045087| innate immune response PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0042493| response to drug ABCC4;ABCC8;PPARG GO:0061614| PPARG GO:0030224| monocyte differentiation PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:1904706| PPARG GO:0016525| negative regulation of angiogenesis ABCC8;PPARG GO:0033189| response to vitamin A PPARG GO:0050872| white fat cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG GO:0042752| regulation of circadian rhythm PPARG 7966:[DB07863 DB04932] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;ADORA2A GO:0042493| response to drug PPARG;ADORA2A GO:0031000| response to caffeine PPARG;ADORA2A GO:0008285| negative regulation of cell proliferation ADORA2A;PPARG;ADORA1 GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0007165| signal transduction ADORA2B;ADORA2A;PPARG;ADORA1 GO:0007186| G-protein coupled receptor signaling pathway ADORA2B;ADORA2A;PPARG;ADORA1 7967:[DB07863 DB00334] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00334|Olanzapine HTR2A;DRD2;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR5A;DRD1;DRD5;HRH2;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;ADRB1;ADRB2;ADRB3;CYP1A2;CYP2D6;FMO3;CYP2C19;CYP3A4;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;DRD3;RXRA GO:0007186| G-protein coupled receptor signaling pathway CHRM4;HTR7;DRD2;ADRA1A;ADRB1;HTR1B;ADRB3;ADRA2A;HTR5A;HTR2C;HTR6;HTR2B;CHRM3;DRD3;PPARG;DRD5;HTR1E;DRD1;ADRA1B;HRH1;HTR1D;CHRM5;CHRM2;HRH2;ADRA2B;ADRB2;HRH4;HTR2A;CHRM1;ADRA2C;DRD4;HTR1A GO:0007165| signal transduction GABRB1;HTR1D;HRH1;GABRQ;CHRM5;GABRE;HRH4;ADRB2;ADRA2B;HTR2A;HRH2;CHRM2;DRD4;GABRA6;HTR1A;CHRM1;ADRA2C;DRD5;HTR1E;DRD1;ADRA1B;GABRB3;GABRA5;CHRM3;GABRP;DRD3;PPARG;GABRD;CHRM4;HTR3A;HTR7;ADRA1A;DRD2;HTR1B;ADRB1;ADRB3;HTR5A;HTR6;HTR2B;HTR2C;ADRA2A GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2;ADRA2A GO:0031100| organ regeneration UGT1A1;PPARG GO:0042593| glucose homeostasis ADRA1B;PPARG;ADRA2A GO:0014070| response to organic cyclic compound PPARG;UGT1A1;CYP1A2 GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;PPARG GO:0010033| response to organic substance CYP1A2;UGT1A1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process NCOA2;PPARG;DRD4 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;PPARG GO:0007623| circadian rhythm HTR7;NCOA2 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DRD3 GO:0007507| heart development PPARG;RXRA;HTR2B GO:0009409| response to cold ADRB3;ADRB1;PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2;DRD2;ADRB2 GO:0042493| response to drug HTR1B;ABCB1;DRD2;ADRA1A;HTR2C;HTR2B;UGT1A1;PPARG;DRD3;GABRG3;DRD1;CYP1A2;HTR2A GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 7968:[DB07863 DB00783] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00783|Estradiol ESR1;ESR2;NR1I2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP3A4;CYP1A2;CYP3A5;CYP3A7;UGT1A1;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes NCOA2 common pathways GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP3A4;CYP1A2;HSD17B2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0045087| innate immune response PPARG;GPER1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;ESR2;ESR1 GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG;GPER1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GPER1;PPARG;NR1I2;RXRA;NCOA2;ESR2;ESRRG GO:0043401| steroid hormone mediated signaling pathway ESR1;GPER1;RXRA;NR1I2;PPARG;ESRRG;ESR2 GO:0006351| transcription, DNA-dependent ESR1;PPARG;NR1I2;RXRA;NCOA2;ESR2;ESRRG GO:0032526| response to retinoic acid RXRA;PPARG;HSD17B2 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0007623| circadian rhythm NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0033189| response to vitamin A CYP1A1;PPARG GO:1904706| GPER1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG;ESRRG;ESR2;ESR1 GO:0001701| in utero embryonic development HSD17B2;RXRA GO:0016032| viral reproduction BECN1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2;ESR1 GO:0010906| regulation of glucose metabolic process NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0032922| circadian regulation of gene expression NCOA2 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RXRA GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESRRG;ESR2;RXRA;NR1I2;PPARG GO:0042493| response to drug ABCB1;ABCG2;BECN1;UGT1A1;CYP1A1;PPARG;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESRRG;ESR2;NCOA2;PPARG;NR1I2;RXRA GO:0007165| signal transduction GPER1;CHRNA4;ESR1;ESR2;PPARG;NR1I2 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0031100| organ regeneration PPARG;UGT1A1 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CYP1A1;RXRA GO:0007186| G-protein coupled receptor signaling pathway GPER1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BECN1;GPER1 GO:0010033| response to organic substance CYP1A1;PPARG;UGT1A1;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;NCOA2 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:1904017| NCOA2 GO:0048511| rhythmic process PPARG;NCOA2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0001890| placenta development PPARG;RXRA;HSD17B2 GO:0015721| bile acid and bile salt transport NCOA2;SLCO1C1;RXRA;ALB;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3 GO:0045475| locomotor rhythm NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG;UGT1A1 7969:[DB07863 DB14543] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;NR3C1 GO:0043065| positive regulation of apoptotic process PPARG;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;NCOA2;PPARG;RXRA GO:0045087| innate immune response PPARG;ANXA1 GO:0006629| lipid metabolic process CYP3A4;CYP11B1;CYP11B2;PPARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RXRA;PPARG;NCOA2 GO:0042493| response to drug ABCG2;ANXA1;HSD11B2;ABCB1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;ANXA1 GO:0042593| glucose homeostasis PPARG;CYP11B1 GO:0032870| cellular response to hormone stimulus CYP11B1;CYP11B2;NCOA2 GO:0007165| signal transduction NR3C1;ANXA1;PPARG GO:0014070| response to organic cyclic compound ANXA1;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1A2 GO:0008217| regulation of blood pressure PPARG;CYP11B1 7970:[DB07863 DB01221] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4;PTGS1 GO:0007507| heart development RXRA;PPARG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;NOS1;DRD2 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;PPARG;RXRA GO:0042493| response to drug HTR2A;PPARG;BCHE;SLC6A2;HTR2C;HTR2B;DRD2;HTR1B GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0007186| G-protein coupled receptor signaling pathway HTR1B;DRD2;CHRM4;HTR2B;HTR2C;OPRK1;HTR1F;CHRM3;PPARG;HTR1E;TACR1;OPRM1;CHRM5;HTR1D;OPRD1;CHRM1;HTR1A;CHRM2;HTR2A GO:0007165| signal transduction CHRNA7;HTR1E;CHRM2;HTR2A;CHRM1;HTR1A;HTR1D;OPRD1;TACR1;CHRM5;OPRM1;OPRK1;HTR1F;HTR2B;HTR2C;HTR3A;CHRM4;DRD2;HTR1B;PPARG;CHRM3 GO:0014070| response to organic cyclic compound TACR1;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;TACR1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG;BCHE;DRD2 GO:0007584| response to nutrient PPARG;BCHE GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C 7971:[DB07863 DB05541] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0042493| response to drug SCN11A;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PPARG 7972:[DB07863 DB00740] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A1;PPARG;CYP1A2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0042493| response to drug CYP1A2;CYP1A1;PPARG;ABCG2 GO:0033189| response to vitamin A PPARG;CYP1A1 7973:[DB07863 DB00297] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway PTGER1;PPARG GO:0007165| signal transduction PTGER1;PPARG 7974:[DB07863 DB00335] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ABCB11;NCOA2;RXRA GO:0007186| G-protein coupled receptor signaling pathway ADRB2;PPARG;ADRB1 GO:0007165| signal transduction ADRB2;ADRB1;PPARG GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0009409| response to cold ADRB1;PPARG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;RXRA;NCOA2 7975:[DB07863 DB14068] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PPARG 7976:[DB07863 DB01285] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;CRH;MC2R GO:0007165| signal transduction PPARG;CRH;MC2R GO:0043627| response to estrogen stimulus PPARG;CRH;CYP27B1 GO:0008285| negative regulation of cell proliferation PPARG;CYP27B1 GO:0001890| placenta development PPARG;RXRA;MC2R GO:0030308| negative regulation of cell growth PPARG;CYP27B1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0035902| response to immobilization stress PPARG;CRH GO:0006766| vitamin metabolic process RXRA;CYP24A1;CYP27B1 GO:0042493| response to drug CRH;PPARG 7977:[DB07863 DB08896] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent FGFR1;MAPK11;RXRA;PPARG;NCOA2;ABL1 GO:0042493| response to drug ABCG2;ABCB1;NTRK1;PPARG;UGT1A1;RET GO:0045893| positive regulation of transcription, DNA-dependent RET;PPARG;RXRA GO:0001701| in utero embryonic development FGFR1;FGFR2;RXRA GO:0016525| negative regulation of angiogenesis PPARG;TEK GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;FGFR2 GO:0016032| viral reproduction KDR;PDGFRA;EPHA2;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;DDR2;PPARG GO:0032526| response to retinoic acid RXRA;PPARG;PDGFRB GO:0055010| ventricular cardiac muscle tissue morphogenesis FGFR2;RXRA GO:0048469| cell maturation PPARG;FGFR1 GO:0006351| transcription, DNA-dependent MAPK11;FGFR1;NCOA2;RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;KIT GO:0007623| circadian rhythm NCOA2;NTRK1 GO:0045165| cell fate commitment PPARG;FGFR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FRK;NCOA2;PPARG;RXRA;FGFR2;FGFR1 GO:0045087| innate immune response PPARG;ABL1;FRK GO:0007507| heart development RXRA;PPARG;TEK;RAF1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;RAF1;FGFR2 GO:0043065| positive regulation of apoptotic process ABL1;PDGFRB;PPARG GO:0071300| cellular response to retinoic acid FGFR2;RET;PPARG GO:0030855| epithelial cell differentiation PPARG;FGFR2 GO:0014070| response to organic cyclic compound UGT1A1;PPARG;PDGFRB GO:0006919| activation of caspase activity RET;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0043627| response to estrogen stimulus TEK;PPARG;PDGFRB GO:0008285| negative regulation of cell proliferation RAF1;PPARG;NTRK1;FRK GO:0010033| response to organic substance TEK;PPARG;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;PDGFRB GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 GO:0007165| signal transduction PDGFRB;PPARG;TEK;BRAF;RAF1;DDR2;RET;MAPK11;KIT GO:0031100| organ regeneration PPARG;UGT1A1 GO:0033993| response to lipid PDGFRB;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 7978:[DB07863 DB00015] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm SERPINE1;NCOA2 GO:0045087| innate immune response PPARG;FGA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;SERPINE1 GO:0008285| negative regulation of cell proliferation PPARG;PLG GO:0007165| signal transduction PLAUR;FGA;PPARG GO:0043388| positive regulation of DNA binding PLAUR;PPARG 7979:[DB07863 DB00752] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways GO:0042493| response to drug PPARG;MAOB;CYP2E1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C9;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG 7980:[DB07863 DB00277] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ADORA2A;RXRA;CPNE1;PARP1;HDAC2 GO:0042493| response to drug ADA;HDAC2;CYP1A2;CYP2E1;PDE3A;ADORA2A;PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;PPARG;RXRA GO:0032922| circadian regulation of gene expression NCOA2;HDAC2 GO:0051289| protein homotetramerization RXRA;HM13 GO:0001701| in utero embryonic development ADA;RXRA GO:0033189| response to vitamin A CYP1A1;PPARG GO:0006351| transcription, DNA-dependent PARP1;HDAC2;NCOA2;RXRA;PPARG;CPNE1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;HDAC2;PPARG;RXRA;NCOA2 GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG GO:0071300| cellular response to retinoic acid PPARG;HDAC2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC2;PARP1;NCOA2;RXRA;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process PDE3A;PPARG;CPNE1;CYP2D6;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;CYP1A2 GO:0001890| placenta development RXRA;PPARG;ADA GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC2 GO:0048511| rhythmic process PPARG;NCOA2;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent HDAC2;PPARG;NCOA2 GO:0031000| response to caffeine PPARG;ADORA2A;HDAC2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;ADORA1;PPARG;ADORA2A GO:0007186| G-protein coupled receptor signaling pathway PDE4A;ADORA2A;ADORA1;PPARG;PDE3A;PDE4B;ADORA2B GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1 GO:0032869| cellular response to insulin stimulus PARP1;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007165| signal transduction PDE4A;PDE4B;ADORA2B;ADORA2A;PPARG;ADORA1;PDE5A;PDE3A 7981:[DB07863 DB12789] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12789|Dinoprost PTGDR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;PTGDR2 GO:0007165| signal transduction PTGDR2;PPARG 7982:[DB07863 DB01244] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01244|Bepridil CACNA1A;CACNA1H;CACNA2D2;ATP1A1;KCNQ1;TNNC1;CALM1;PDE1B;PDE1A;KCNH2;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0030224| monocyte differentiation PDE1B;PPARG GO:0042493| response to drug PPARG;ABCB1;ATP1A1 GO:0055010| ventricular cardiac muscle tissue morphogenesis RXRA;TNNC1 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0008217| regulation of blood pressure PPARG;ATP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CALM1;PDE1A;PDE1B GO:0007165| signal transduction PDE1B;PDE1A;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H 7983:[DB07863 DB01175] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0042493| response to drug ADRA1A;SLC6A3;SLC6A2;PPARG;SLC6A4 GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0010033| response to organic substance PPARG;SLC6A4 GO:0007584| response to nutrient SLC6A4;PPARG GO:0007186| G-protein coupled receptor signaling pathway HRH1;CHRM1;ADRA1A;PPARG GO:0007165| signal transduction PPARG;ADRA1A;HRH1;CHRM1 7984:[DB07863 DB00295] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;PPARG;OPRK1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0045087| innate immune response PPARG;LY96 GO:0006629| lipid metabolic process CYP3A4;UGT2B7;PPARG;CYP2D6 GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug PPARG;UGT1A1;ABCB1 7985:[DB07863 DB01393] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes RXRA;PPARG common pathways GO:0055010| ventricular cardiac muscle tissue morphogenesis RXRA GO:0032526| response to retinoic acid PPARG;RXRA GO:0048469| cell maturation PPARG GO:0006351| transcription, DNA-dependent PPARD;PPARA;NCOA2;NR1I2;RXRB;RXRA;PPARG;RXRG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway RXRG;RXRA;NR1I2;RXRB;PPARG;PPARD;PPARA GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:1905563| PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;PPARD GO:0008203| cholesterol metabolic process RXRA;PPARD GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARA;PPARD;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARD;PPARG;RXRA;NCOA2 GO:0045087| innate immune response PPARG GO:0035902| response to immobilization stress CYP1A1;PPARG GO:1901522| RXRA;RXRG GO:0042953| lipoprotein transport PPARG GO:0019048| virus-host interaction RXRA GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;RXRG;NCOA2;NR1I2;RXRB;RXRA;PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0009409| response to cold PPARG GO:0009612| response to mechanical stimulus PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0030224| monocyte differentiation PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0048384| retinoic acid receptor signaling pathway RXRG;RXRA;RXRB GO:0006766| vitamin metabolic process RXRA GO:0061614| PPARG GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;NCOA2;RXRA;NR1I2;RXRB;PPARG;RXRG GO:0042493| response to drug PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA;PPARD;PPARA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0050872| white fat cell differentiation PPARG GO:0001701| in utero embryonic development RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;PPARA;RXRA;NR1I2;RXRB;PPARG;RXRG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:1904706| PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA GO:0033189| response to vitamin A PPARG;CYP1A1;PPARD GO:0071455| cellular response to hyperoxia PPARG GO:0032922| circadian regulation of gene expression NCOA2;PPARA GO:0051289| protein homotetramerization RXRG;RXRA GO:0030522| intracellular receptor mediated signaling pathway NCOA2;RXRB;NR1I2;PPARD;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0016032| viral reproduction RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0045994| positive regulation of translational initiation by iron RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0015909| long-chain fatty acid transport PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:1905461| PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0060038| cardiac muscle cell proliferation RXRA GO:0019216| regulation of lipid metabolic process PPARA;RXRA;CYP1A1;PPARG;NCOA2 GO:0007566| embryo implantation RXRA;PPARD GO:0007165| signal transduction PPARG;NR1I2 GO:0001893| maternal placenta development RXRA GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0033993| response to lipid PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0060528| secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development RXRA GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG GO:0055012| ventricular cardiac muscle cell differentiation RXRA GO:0014070| response to organic cyclic compound PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0006919| activation of caspase activity PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0007584| response to nutrient PPARG GO:0048511| rhythmic process PPARA;NCOA2;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARD;NCOA2;PPARG;NR1I2 GO:0031000| response to caffeine PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0010033| response to organic substance PPARD;PPARG;CYP1A1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0015721| bile acid and bile salt transport SLCO1B1;RXRA;NCOA2 GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD GO:0001890| placenta development PPARD;PPARG;RXRA GO:0019395| fatty acid oxidation PPARG;PPARD GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG 7986:[DB07863 DB00492] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure PPARG;ACE 7987:[DB07863 DB05443] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG GO:0007165| signal transduction OPRK1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG 7988:[DB07863 DB00563] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00563|Methotrexate DHFR;DHFR;AOX1;MTHFR;PGD;FPGS;TYMS;ATIC;GGH;CYP3A4;ALB;ABCC3;ABCC4;ABCC1;SLC22A6;ABCC10;SLC22A8;ABCC2;ABCB1;SLCO1A2;SLC16A1;ABCC11;SLCO1B3;SLC22A11;SLCO1C1;SLCO3A1;ABCG2;SLC22A7;SLC46A1;SLCO1B1;SLCO4C1;SLC19A1;FOLR1 common genes common pathways GO:0007623| circadian rhythm NCOA2;TYMS GO:0006629| lipid metabolic process PPARG;SLC16A1;CYP3A4 GO:0042493| response to drug GGH;MTHFR;ABCC4;PPARG;TYMS;ABCC1;ABCG2;ABCC2;ABCB1 GO:0033189| response to vitamin A PPARG;TYMS GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0031100| organ regeneration ATIC;PPARG;FPGS GO:0042593| glucose homeostasis SLC16A1;PPARG GO:0014070| response to organic cyclic compound PPARG;TYMS;ABCC4 GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1C1;ABCC3;ALB;SLCO1B3;SLCO1B1;SLCO1A2 GO:0010033| response to organic substance PPARG;ABCC4 GO:0043627| response to estrogen stimulus PPARG;ABCC2 7989:[DB07863 DB00217] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;ADRB2 GO:0009409| response to cold PPARG;ADRB3;ADRB1;ADRB2 GO:0007165| signal transduction PPARG;ADRA2A;ADRB3;ADRB1;ADRA2C;ADRB2;ADRA2B GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway ADRA2C;ADRA2B;ADRB2;ADRA2A;ADRB3;ADRB1;PPARG 7990:[DB07863 DB01281] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01281|Abatacept CD80;CD86 common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;CD86;CD80 GO:0016032| viral reproduction CD80;RXRA;CD86 7991:[DB07863 DB00709] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00709|Lamivudine pol;DCK;CMPK1;PGK1;NME1;NME2;PCYT1A;PCYT2;NT5C;ALB;ABCC1;SLC22A6;ABCG2;SLC22A1;SLC22A2;SLC22A3;ABCB1;ABCC4;ABCC3;ABCC2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA;ABCC3;NCOA2 GO:0008285| negative regulation of cell proliferation NME1;PPARG GO:0010033| response to organic substance PPARG;ABCC4 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0014070| response to organic cyclic compound PPARG;ABCC4 GO:0030855| epithelial cell differentiation PPARG;PGK1 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0043388| positive regulation of DNA binding NME1;PPARG GO:0016525| negative regulation of angiogenesis PPARG;PGK1 GO:0006355| regulation of transcription, DNA-dependent NME2;RXRA;PPARG;NCOA2 GO:0042493| response to drug PPARG;ABCC1;ABCC2;ABCG2;ABCB1;NME1;ABCC4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NME2;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process PCYT2;PPARG;PCYT1A GO:0006351| transcription, DNA-dependent PPARG;RXRA;NCOA2;NME2 7992:[DB07863 DB01090] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways GO:0007165| signal transduction CHRNA10;CHRNA3;CHRNB4;PPARG 7993:[DB07863 DB00361] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG 7994:[DB07863 DB00495] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00495|Zidovudine pol;TERT;CYP2A6;CYP2C8;CYP2C9;CYP3A4;TK1;UGT2B7;UGT1A1;ALB;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLC28A1;SLC29A2;ABCB1;ABCC4;ABCC5;ABCG2 common genes common pathways GO:0051289| protein homotetramerization TK1;RXRA GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;PPARG;ABCC4 GO:0006629| lipid metabolic process CYP3A4;UGT2B7;PPARG;CYP2C9 GO:0042594| response to starvation UGT1A1;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance ABCC4;UGT1A1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG;ABCC4 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 7995:[DB07863 DB09262] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM3;CHRM1;CHRM2 GO:0007165| signal transduction CHRM1;CHRM2;PPARG;CHRM3 7996:[DB07863 DB01088] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PDE4C;PDE4B;PTGIR;PPARG;PTGDR2;PDE4D;PDE4A;PTGER1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PTGIR GO:0007165| signal transduction PDE4D;PDE4A;PTGER1;PTGDR2;PTGIR;PPARG;PDE4C;PDE4B GO:0015721| bile acid and bile salt transport SLCO2B1;NCOA2;RXRA 7997:[DB07863 DB05294] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes common pathways GO:0033993| response to lipid EGFR;PPARG GO:0007165| signal transduction RET;TEK;EGFR;PPARG GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0043627| response to estrogen stimulus TEK;PPARG GO:0010033| response to organic substance TEK;PPARG GO:0006919| activation of caspase activity PPARG;RET GO:0014070| response to organic cyclic compound PPARG;EGFR GO:0030855| epithelial cell differentiation PPARG;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;NCOA2;RXRA;PPARG;VEGFA GO:0071300| cellular response to retinoic acid PPARG;PTK6;RET GO:0007507| heart development RXRA;PPARG;TEK GO:0045087| innate immune response PPARG;PTK6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;RXRA;PPARG;EGFR GO:0007623| circadian rhythm EGFR;NCOA2 GO:0048469| cell maturation PPARG;VEGFA GO:0001701| in utero embryonic development VEGFA;RXRA GO:0016525| negative regulation of angiogenesis PPARG;TEK GO:0042493| response to drug RET;ABCC1;PPARG;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent RET;EGFR;PPARG;RXRA GO:0030224| monocyte differentiation PPARG;VEGFA 7998:[DB07863 DB00544] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0014070| response to organic cyclic compound TYMS;PPARG;ABCC4;CYP1A2 GO:0010033| response to organic substance ABCC4;CYP1A2;PPARG GO:0015721| bile acid and bile salt transport ALB;RXRA;ABCC3;NCOA2 GO:0032869| cellular response to insulin stimulus PPAT;PPARG GO:0031100| organ regeneration PPAT;PPARG GO:0042493| response to drug PPARG;TYMS;ABCG2;CYP1A2;MTHFR;PPAT;ABCC4 GO:0033189| response to vitamin A TYMS;PPARG GO:0051289| protein homotetramerization RXRA;PPAT GO:0007623| circadian rhythm NCOA2;TYMS GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2C9 GO:0035902| response to immobilization stress PPARG;CYP1A2 7999:[DB07863 DB00542] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure ACE;PPARG GO:0042493| response to drug PPARG;MTHFR 8000:[DB07863 DB08870] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways GO:0007165| signal transduction PPARG;TNFRSF8 GO:0008285| negative regulation of cell proliferation TNFRSF8;PPARG GO:0043065| positive regulation of apoptotic process PPARG;TNFRSF8 GO:0006629| lipid metabolic process PPARG;CYP3A4 8001:[DB07863 DB08873] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08873|Boceprevir CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug PPARG;ABCB1 8002:[DB07863 DB09119] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0007165| signal transduction PPARG;P2RX4 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;PPARG GO:0008217| regulation of blood pressure P2RX4;PPARG 8003:[DB07863 DB00201] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes common pathways GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007165| signal transduction PDE6B;ADORA2A;PPARG;ADORA1;PDE2A;ATM;PDE5A;PDE8A;PDE3A;PIK3CD;PDE11A;PDE7A;PDE4C;PDE4B;PDE9A;ITPR1;PDE7B;PDE6C;PDE1C;PIK3CB;PDE4A;PDE4D;PDE1A;PDE8B;PDE10A;ITPR2;PDE3B;PDE1B;PDE6A GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ITPR3;PDE4D;PDE4A;PIK3CB;PIK3CA;PDE1B;PDE3B;PDE10A;PDE8B;PDE1A;PDE3A;PDE8A;PDE2A;ADORA1;PPARG;ADORA2A;PDE7B;PDE4B;PDE4C;PDE11A;PDE7A GO:0032869| cellular response to insulin stimulus PDE3B;PRKDC;PPARG GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADORA1;ADORA2A;CYP1B1 GO:0031000| response to caffeine RYR1;PPARG;ADORA2A GO:0048511| rhythmic process PRKDC;PPARG;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0043065| positive regulation of apoptotic process PPARG;ATM;CYP1B1;PRKDC GO:0045944| positive regulation of transcription from RNA polymerase II promoter PRKDC;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP2D6;PDE3A;PPARG;CYP2C9;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0007507| heart development PRKDC;RXRA;PPARG;ATM GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;PDE2A;NCOA2 GO:0045087| innate immune response PRKDC;PIK3CB;PIK3CA;PIK3CD;PPARG GO:0051289| protein homotetramerization RYR1;RXRA GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PDE3B;PPARG GO:0042752| regulation of circadian rhythm PPARG;PRKDC GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1;CYP1A1;PPARG;ADORA2A;PDE3A GO:0006355| regulation of transcription, DNA-dependent PDE8A;NCOA2;PPARG;RXRA;ADORA2A GO:0030224| monocyte differentiation PDE2A;PPARG;PDE1B 8004:[DB07863 DB00972] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00972|Azelastine HRH1;CYP1A2;CYP3A4;CYP2C19;CYP1A1;CYP3A5;CYP2C9;CYP2C8;CYP2D6;CYP2A6;CYP2B6;CYP2E1;ABCB1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1;CYP1A2 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CYP1A1;RXRA GO:0007186| G-protein coupled receptor signaling pathway HRH1;PPARG GO:0007165| signal transduction HRH1;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0042493| response to drug ABCB1;PPARG;CYP1A1;CYP2E1;CYP1A2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG 8005:[DB07863 DB00774] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:0010033| response to organic substance PPARG;CA2 GO:0008217| regulation of blood pressure ATP1A1;PPARG GO:0043627| response to estrogen stimulus CA2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;KCNMA1 GO:0042493| response to drug PPARG;ATP1A1;CA9 8006:[DB07863 DB01567] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0007165| signal transduction GABRB3;GABRB1;GABRE;GABRP;GABRD;PPARG;GABRA5;GABRR2 GO:0042493| response to drug GABRG3;PPARG 8007:[DB07863 DB00480] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0007566| embryo implantation PTGS2;RXRA GO:0010033| response to organic substance PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG 8008:[DB07863 DB00771] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00771|Clidinium CHRM1 common genes common pathways GO:0007165| signal transduction CHRM1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;CHRM1 8009:[DB07863 DB00659] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0042493| response to drug PPARG;GABRG3;GRIN2A GO:0043065| positive regulation of apoptotic process PPARG;GRIN2A;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NCOA2;RXRA;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GRM5 GO:0007165| signal transduction GABRA5;GABRP;GABRD;PPARG;GABRB3;GABRQ;GABRB1;GRM5;GABRE;GABRA6 8010:[DB07863 DB00412] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes RXRA;PPARG common pathways GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0042593| glucose homeostasis PPARG GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0060528| secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development RXRA GO:0043010| camera-type eye development RXRA GO:0033993| response to lipid PPARG GO:0001893| maternal placenta development RXRA GO:0007165| signal transduction PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1905461| PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG GO:0019216| regulation of lipid metabolic process PPARA;PPARG;RXRA;NCOA2 GO:0007566| embryo implantation PPARD;RXRA GO:0060038| cardiac muscle cell proliferation RXRA GO:0045994| positive regulation of translational initiation by iron RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD GO:0015721| bile acid and bile salt transport ABCB11;SLCO1B1;NCOA2;RXRA;ALB GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development RXRA;PPARG;PPARD GO:0019395| fatty acid oxidation PPARG;PPARD GO:0043627| response to estrogen stimulus PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0007584| response to nutrient ACSL4;PPARG GO:0048511| rhythmic process NCOA2;PPARG;PPARA GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance PPARG;CYP1A2;PPARD GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0031000| response to caffeine PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1 GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG;NCOA2 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0055012| ventricular cardiac muscle cell differentiation RXRA GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0030855| epithelial cell differentiation PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0043065| positive regulation of apoptotic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRG;NCOA2;PPARG;RXRA;RXRB;PPARA GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG GO:0009409| response to cold PPARG GO:0007507| heart development PPARA;PPARD;PPARG;RXRA GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARD;PPARG;RXRA;NCOA2 GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process CYP2D6;ACSL4;PPARG;CYP2C9;PTGS1;PPARD;CYP1A2;PPARA;CYP3A4 GO:0019048| virus-host interaction RXRA GO:0042594| response to starvation PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:1901522| RXRG;RXRA GO:0042953| lipoprotein transport PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0008203| cholesterol metabolic process RXRA;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;PPARD GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0048469| cell maturation PPARG GO:0055010| ventricular cardiac muscle tissue morphogenesis RXRA GO:0032526| response to retinoic acid RXRA;PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARD;RXRG;PPARG;RXRB;RXRA GO:0006351| transcription, DNA-dependent PPARD;PPARA;RXRG;NCOA2;PPARG;RXRB;RXRA GO:0051289| protein homotetramerization RXRA;RXRG GO:0030522| intracellular receptor mediated signaling pathway PPARD;PPARA;NCOA2;RXRB GO:0032922| circadian regulation of gene expression NCOA2;PPARA GO:0071455| cellular response to hyperoxia PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0016032| viral reproduction RXRA GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;RXRB;PPARG;RXRG;PPARD;PPARA GO:0001701| in utero embryonic development RXRA GO:0050872| white fat cell differentiation PPARG GO:0033189| response to vitamin A PPARD;PPARG GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA GO:0016525| negative regulation of angiogenesis PPARG GO:1904706| PPARG GO:0042493| response to drug PPARG;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARD;RXRG;RXRB;RXRA;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;PPARA;PPARD GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0030224| monocyte differentiation PPARG GO:0061614| PPARG GO:0006766| vitamin metabolic process RXRA GO:0048384| retinoic acid receptor signaling pathway RXRG;RXRA;RXRB 8011:[DB07863 DB01608] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0007186| G-protein coupled receptor signaling pathway DRD1;ADRA1B;ADRA2A;PPARG GO:0042593| glucose homeostasis ADRA1B;PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007165| signal transduction AR;ADRA1B;DRD1;PPARG;ADRA2A GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;AR GO:0042493| response to drug PPARG;DRD1 GO:0045893| positive regulation of transcription, DNA-dependent AR;RXRA;PPARG GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0001701| in utero embryonic development AR;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;RXRA;PPARG GO:0006351| transcription, DNA-dependent AR;NCOA2;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway AR;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;RXRA;PPARG;NCOA2 8012:[DB07863 DB01119] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010033| response to organic substance PPARG;CA2 GO:0008217| regulation of blood pressure PPARG;ATP1A1 GO:0043065| positive regulation of apoptotic process PPARG;KCNMA1 GO:0042493| response to drug KCNJ11;ATP1A1;PPARG 8013:[DB07863 DB04908] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04908|Flibanserin HTR1A;HTR2A;DRD4;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2A;PPARG GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0016032| viral reproduction RXRA;HTR2A GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0048511| rhythmic process PPARG;NCOA2;DRD4 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;DRD4;HTR1A;PPARG GO:0007165| signal transduction HTR2A;DRD4;HTR1A;PPARG 8014:[DB07863 DB00842] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways GO:0007165| signal transduction GABRQ;GABRB1;GABRE;GABRA6;GABRB3;GABRA5;GABRR2;GABRP;GABRD;PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 GO:0042493| response to drug PPARG;GABRG3 GO:0006629| lipid metabolic process CYP3A4;UGT2B7;PPARG 8015:[DB07863 DB00184] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0042493| response to drug CYP1A1;PPARG;MAOB;CYP2E1;CYP1A2 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP2C9;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0010033| response to organic substance CYP1A1;PPARG;CYP1A2 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;CYP1A1;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction CHRNA10;CHRNA3;CHRNB2;CHRNB4;PPARG;CHRNA9;CHRNB3;CHRNA2;CHRNA5;CHRNA4;CHRNA7;CHRNA6 8016:[DB07863 DB04630] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0008217| regulation of blood pressure PPARG;CYP11B1 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;RXRA GO:0007165| signal transduction PPARG;NR3C2;NR3C1 GO:0042593| glucose homeostasis CYP11B1;PPARG GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;RXRA;PPARG;NR3C2 GO:0042493| response to drug ABCB1;PPARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;RXRA;PPARG;NCOA2;NR3C2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;RXRA;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C2;NR3C1 GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;NR3C2;NR3C1 8017:[DB07863 DB00482] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00482|Celecoxib PTGS2;PDPK1;CA2;CA3;ABCB5;ABCG2;ABCB1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;ABCC4;ABCB11 common genes common pathways GO:0042493| response to drug ABCC4;PTGS2;ABCG2;ABCB1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;PDPK1;NCOA2 GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;PDPK1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;PTGS2;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0014070| response to organic cyclic compound PPARG;ABCC4;PTGS2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PPARG;CA2;PTGS2;ABCC4 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ABCB11 GO:0032869| cellular response to insulin stimulus PPARG;PDPK1 GO:0007566| embryo implantation RXRA;PTGS2 8018:[DB07863 DB01035] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;BCHE GO:0045892| negative regulation of transcription, DNA-dependent DNMT1;NCOA2;PPARG GO:0007584| response to nutrient PPARG;BCHE GO:0042493| response to drug BCHE;PPARG GO:0006355| regulation of transcription, DNA-dependent DNMT1;NCOA2;PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;DNMT1 GO:0006629| lipid metabolic process CYP2D6;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;DNMT1 8019:[DB07863 DB00648] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;ESR1;AR GO:0006355| regulation of transcription, DNA-dependent PGR;NCOA2;PPARG;RXRA;AR;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR;RXRA;PPARG;PGR GO:0001701| in utero embryonic development AR;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;RXRA;PPARG;PGR GO:0006351| transcription, DNA-dependent PGR;PPARG;RXRA;NCOA2;AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR;ESR1 GO:0008203| cholesterol metabolic process RXRA;FDX1 GO:0006629| lipid metabolic process PPARG;FDX1;CYP11B1;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;NCOA2;PPARG;RXRA;AR;ESR1 GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0008217| regulation of blood pressure PPARG;CYP11B1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007165| signal transduction PGR;PPARG;AR;ESR1 GO:0032870| cellular response to hormone stimulus CYP11B1;NCOA2 GO:0042593| glucose homeostasis CYP11B1;PPARG 8020:[DB07863 DB01238] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0019216| regulation of lipid metabolic process PPARG;DRD3;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway HTR7;CHRM4;HTR1B;ADRA1A;DRD2;ADRA2A;HTR6;HTR2C;CHRM3;DRD3;PPARG;DRD5;HTR1E;DRD1;ADRA1B;HTR1D;HRH1;CHRM5;CHRM2;HTR2A;ADRA2B;ADRA2C;CHRM1;HTR1A;DRD4 GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA2A;PPARG;ADRA1B GO:0007165| signal transduction ADRA1A;DRD2;HTR1B;CHRM4;HTR3A;HTR7;ADRA2A;HTR6;HTR2C;CHRM3;PPARG;DRD3;HTR1E;DRD5;ADRA1B;DRD1;CHRM5;HTR1D;HRH1;CHRM1;ADRA2C;DRD4;HTR1A;CHRM2;ADRA2B;HTR2A GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 GO:0048511| rhythmic process PPARG;NCOA2;DRD4 GO:0007623| circadian rhythm NCOA2;HTR7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2;DRD2 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;DRD3;PPARG;NCOA2 GO:0042493| response to drug HTR2A;DRD1;PPARG;DRD3;HTR2C;DRD2;ADRA1A;HTR1B GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD3;DRD2 GO:0042752| regulation of circadian rhythm PPARG;DRD4 8021:[DB07863 DB06710] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;ESR1;AR GO:0001701| in utero embryonic development RXRA;AR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;NCOA2;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;AR;ESR1 GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;ESR1;AR GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2;SLCO1A2 GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007165| signal transduction PPARG;ESR1;AR 8022:[DB07863 DB07477] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB07477|Felbinac CTSL common genes common pathways 8023:[DB07863 DB01156] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes common pathways GO:0042493| response to drug SLC6A3;SLC6A2;PPARG;CYP2E1 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;CYP3A4 GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0007165| signal transduction CHRNA3;PPARG 8024:[DB07863 DB00496] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway CHRM2;CHRM1;CHRM5;PPARG;CHRM3;CHRM4 GO:0007165| signal transduction CHRM4;PPARG;CHRM3;CHRM2;CHRM1;CHRM5 8025:[DB07863 DB00318] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;PPARG;OPRK1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance PPARG;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4;UGT2B7 GO:0042493| response to drug PPARG;UGT1A1 8026:[DB07863 DB00443] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways GO:0007165| signal transduction PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;NCOA2;PPARG;RXRA GO:0042493| response to drug PPARG;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;NR3C1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006351| transcription, DNA-dependent NR3C1;NCOA2;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR3C1 8027:[DB07863 DB01217] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0042493| response to drug CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP1A2;CYP3A4 8028:[DB07863 DB01622] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;RXRA;PPARG GO:0042493| response to drug HTR2A;DRD1;PPARG;ADRA1A;DRD2 GO:0032922| circadian regulation of gene expression DRD2;NCOA2 GO:0016032| viral reproduction HTR2A;RXRA GO:0007186| G-protein coupled receptor signaling pathway DRD2;ADRA1A;PPARG;ADRA1B;DRD1;HTR1A;HTR2A GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0007165| signal transduction PPARG;ADRA1A;DRD2;HTR2A;HTR1A;DRD1;ADRA1B GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG 8029:[DB07863 DB09286] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0048511| rhythmic process PPARG;NCOA2;DRD4 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0007165| signal transduction DRD4;HTR2A;ADRA1B;DRD1;ADRA1D;PPARG;DRD3;ADRA1A;DRD2;ADRA2A;HTR2B GO:0042593| glucose homeostasis PPARG;ADRA2A;ADRA1B GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;DRD1;DRD4;HTR2A;ADRA1A;DRD2;ADRA2A;HTR2B;ADRA1D;PPARG;DRD3 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;DRD3 GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0016032| viral reproduction HTR2A;RXRA GO:0042493| response to drug DRD2;ADRA1A;HTR2B;DRD3;PPARG;DRD1;HTR2A GO:0007507| heart development HTR2B;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;RXRA;DRD3;PPARG 8030:[DB07863 DB01062] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0007165| signal transduction PPARG;CHRM3;CHRM2;CHRM1 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;PPARG;CHRM2;CHRM1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG 8031:[DB07863 DB00780] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways GO:0042493| response to drug ABAT;MAOB;PPARG;CYP2E1 GO:0006629| lipid metabolic process PPARG;CYP2D6;CYP3A4 8032:[DB07863 DB01320] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0042493| response to drug PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0015721| bile acid and bile salt transport ALB;RXRA;NCOA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 8033:[DB07863 DB00500] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0042493| response to drug PTGS2;PPARG GO:0051289| protein homotetramerization TDO2;RXRA GO:0006629| lipid metabolic process PPARG;PTGS1;PTGS2 GO:0009612| response to mechanical stimulus PPARG;MPO GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0007566| embryo implantation PTGS2;RXRA 8034:[DB07863 DB00804] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;CYP1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway CHRM1;CHRM2;PPARG GO:0007165| signal transduction PPARG;CHRM1;CHRM2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0042493| response to drug PPARG;CYP1A1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0035902| response to immobilization stress PPARG;CYP1A1 8035:[DB07863 DB01115] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01115|Nifedipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CALM1;KCNA1;CACNA1H;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2A6;CYP2C8;CYP2D6;CYP2E1;CYP1A1;CYP2B6;ABCC3;ABCB1;ABCC2;SLCO1B1;ABCB11 common genes common pathways GO:0043010| camera-type eye development RXRA;CYP1A1;CACNA1C GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2;ABCC2 GO:0007165| signal transduction PPARG;NR1I2 GO:0007186| G-protein coupled receptor signaling pathway CALM1;PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;ABCC3;NCOA2;RXRA GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG;NR1I2 GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;NR1I2;PPARG GO:0007507| heart development CACNA1C;PPARG;RXRA GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PPARG;CYP2D6 GO:0006351| transcription, DNA-dependent RXRA;NR1I2;PPARG;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1I2;PPARG GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;RXRA;PPARG GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;RXRA;NR1I2 GO:0042493| response to drug ABCB1;ABCC2;PPARG;CYP1A1;CYP1A2;CYP2E1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA 8036:[DB07863 DB09118] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0043627| response to estrogen stimulus LDHA;PPARG GO:0007584| response to nutrient LDHA;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound PPARG;LDHA;CYP1A2 GO:0007165| signal transduction GABRB3;GABRE;GABRB1;GABRQ;GABRA6;GABRA5;PPARG;GABRD;GABRP GO:0042493| response to drug LDHA;PPARG;CYP1A2;GABRG3 GO:0043065| positive regulation of apoptotic process PPARG;LDHA GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;CYP3A4;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A2 8037:[DB07863 DB11943] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP3A4 GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug CYP2E1;PPARG;UGT1A1;ABCG2 8038:[DB07863 DB01558] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01558|Bromazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug GABRG3;CYP1A2;CYP2E1;PPARG GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0007165| signal transduction GABRA5;GABRR2;GABRP;GABRD;PPARG;GABRQ;GABRB1;GABRE;GABRA6;GABRB3 8039:[DB07863 DB08932] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes common pathways GO:0007165| signal transduction EDNRA;PPARG;EDNRB GO:0007186| G-protein coupled receptor signaling pathway EDNRB;PPARG;EDNRA GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0008217| regulation of blood pressure EDNRB;PPARG;EDNRA GO:0014070| response to organic cyclic compound EDNRB;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;EDNRB GO:0007507| heart development RXRA;EDNRA;PPARG GO:0001701| in utero embryonic development EDNRA;RXRA 8040:[DB07863 DB13975] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0042493| response to drug PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG 8041:[DB07863 DB00042] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;VAMP2 8042:[DB07863 DB00254] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;PADI4 GO:0042493| response to drug PPARG;B2M GO:0006351| transcription, DNA-dependent PPARG;PADI4;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045087| innate immune response PPARG;PADI4;B2M 8043:[DB07863 DB13955] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes NCOA2 common pathways GO:1904017| NCOA2 GO:0048511| rhythmic process PPARG;NCOA2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0008285| negative regulation of cell proliferation GPER1;CYP1B1;PPARG;BECN1 GO:0010033| response to organic substance CYP1A2;UGT1A1;PPARG;CYP1A1 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1C1;NCOA2;RXRA;SLCO1A2;SLCO1B1;SLCO1B3 GO:0001890| placenta development PPARG;RXRA;HSD17B2 GO:0045475| locomotor rhythm NCOA2 GO:0014070| response to organic cyclic compound UGT1A1;PPARG;CYP1A1;CYP1A2 GO:0007165| signal transduction ESR2;NR1I2;PPARG;CHRNA4;GPER1;ESR1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway GPER1;PPARG GO:0019216| regulation of lipid metabolic process RXRA;PPARG;CYP1A1;NCOA2 GO:0001701| in utero embryonic development RXRA;HSD17B2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESRRG;PPARG;NR1I2;RXRA;ESR1 GO:1904706| PPARG;GPER1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0032922| circadian regulation of gene expression NCOA2 GO:0030522| intracellular receptor mediated signaling pathway NR1I2;NCOA2 GO:0010906| regulation of glucose metabolic process NCOA2 GO:0016032| viral reproduction BECN1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2;ESR1 GO:0048384| retinoic acid receptor signaling pathway ESRRG;RXRA GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA;NCOA2;ESR2;ESRRG;ESR1 GO:0042493| response to drug CYP1A2;ABCB1;ABCG2;UGT1A1;BECN1;PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;ESRRG;PPARG;RXRA;NR1I2 GO:0045087| innate immune response GPER1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;RXRA;PPARG;NCOA2;ESR1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;HSD17B2;CYP2C9;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GPER1;ESR1;ESR2;ESRRG;NR1I2;RXRA;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process GPER1;CYP1B1;PPARG GO:0032526| response to retinoic acid RXRA;PPARG;HSD17B2 GO:0006351| transcription, DNA-dependent ESR1;RXRA;NR1I2;PPARG;NCOA2;ESR2;ESRRG GO:0043401| steroid hormone mediated signaling pathway ESR1;GPER1;NR1I2;RXRA;PPARG;ESRRG;ESR2 GO:0007623| circadian rhythm NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;RXRA GO:0030308| negative regulation of cell growth ESR2;PPARG 8044:[DB07863 DB00546] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0007165| signal transduction GABRA5;GABRR2;GABRP;GABRD;PPARG;GABRB3;GABRB1;GABRE 8045:[DB07863 DB14700] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14700|Damoctocog alfa pegol F8 common genes common pathways 8046:[DB07863 DB00418] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0042493| response to drug PPARG;CYP1A2;GRIN2A GO:0043065| positive regulation of apoptotic process GRIN1;GRIN2A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;GRIN1 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007165| signal transduction GABRA5;PPARG;GRIA2;CHRNA4;CHRNA7;GABRA6 8047:[DB07863 DB00428] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;NCOA2 GO:0043010| camera-type eye development CYP1A1;RXRA GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A1;CYP1A2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A1;PPARG;CYP1A2;CYP2E1 GO:0033189| response to vitamin A PPARG;CYP1A1 8048:[DB07863 DB09244] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR1A;PPARG;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0007165| signal transduction PPARG;ADRA2A;HTR1A 8049:[DB07863 DB11718] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CCND1;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0006351| transcription, DNA-dependent NCOA2;CCND1;PPARG;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;CCND1;RXRA GO:0006355| regulation of transcription, DNA-dependent PPARG;CCND1;RXRA;NCOA2 GO:0042493| response to drug PPARG;CCND1 GO:0007165| signal transduction PPARG;BRAF GO:0031100| organ regeneration PPARG;CCND1 GO:0043627| response to estrogen stimulus PPARG;CCND1 GO:0010033| response to organic substance CCND1;PPARG GO:0014070| response to organic cyclic compound PPARG;CCND1 8050:[DB07863 DB01235] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;DRD3;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;DRD3;RXRA;NCOA2 GO:0007623| circadian rhythm NCOA2;DDC GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0032922| circadian regulation of gene expression DRD3;NCOA2;DRD2 GO:0042493| response to drug DRD3;PPARG;DRD2;DRD1 GO:0007165| signal transduction DRD1;DRD5;DRD4;DRD2;PPARG;DRD3 GO:0007186| G-protein coupled receptor signaling pathway DRD3;PPARG;DRD2;DRD4;DRD5;DRD1 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;DRD3;PPARG GO:0048511| rhythmic process PPARG;NCOA2;DRD4 GO:0008285| negative regulation of cell proliferation DRD2;PPARG 8051:[DB07863 DB02709] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes PPARG common pathways GO:0016032| viral reproduction ITGA5;ITGB3;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;PPARG;AKT1;ESR1 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0030522| intracellular receptor mediated signaling pathway AHR;NCOA2;NR1I2;NR1I3;PPARA GO:0071455| cellular response to hyperoxia PPARG GO:0032922| circadian regulation of gene expression AHR;NCOA2;PPARA GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A PPARG;CYP1A1 GO:1904706| PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1I2;ESR1;PPARA;NR1I3 GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0050872| white fat cell differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1I2;RXRA;AHR;PPARA;ESR1;AKT1 GO:0042493| response to drug SNCA;PPARG;CYP1A1;CYP1A2;PTGS2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;AHR;RXRA;NR1I2;PPARG;KHSRP;CSNK2A1;NR1I3;ESR1;PPARA GO:0061614| PPARG GO:0030224| monocyte differentiation PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG GO:0009409| response to cold PPARG GO:0043065| positive regulation of apoptotic process PPARG;APP;SNCA;CYP1B1;PTGS2;AKT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AKT1;NR1I3;PPARA;ESR1;NCOA2;AHR;APP;RXRA;NR1I2;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042594| response to starvation PPARG GO:0006629| lipid metabolic process PPARG;ALOX15;CYP1A2;PTGS2;CYP3A4;PPARA;PTGS1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0042953| lipoprotein transport PPARG GO:0045087| innate immune response APP;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter SNCA;PPARG;RXRA;NCOA2;APP;ESR1;PPARA GO:0007507| heart development PPARG;RXRA;PPARA GO:0045165| cell fate commitment PPARG GO:0030308| negative regulation of cell growth PPARG GO:0008203| cholesterol metabolic process RXRA;APP GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;AHR;ESR1 GO:0007623| circadian rhythm NCOA2;MTNR1B;MTNR1A GO:0043401| steroid hormone mediated signaling pathway NR1I3;PPARA;ESR1;PPARG;NR1I2;RXRA GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0071306| cellular response to vitamin E PPARG GO:0006351| transcription, DNA-dependent NR1I2;RXRA;PPARG;AHR;NCOA2;KHSRP;ESR1;PPARA;NR1I3;CSNK2A1 GO:0048469| cell maturation PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;RXRA GO:0055088| lipid homeostasis PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0045600| positive regulation of fat cell differentiation AKT1;PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG;AKT1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;APP;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;AKT1;PPARG;CYP1A1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0045892| negative regulation of transcription, DNA-dependent AHR;NCOA2;PPARG;NR1I2;NR1I3 GO:0008217| regulation of blood pressure PTGS1;PTGS2;PPARG GO:0031000| response to caffeine PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARA;CSNK2A1;PPARG;NCOA2;AHR GO:0007584| response to nutrient PPARG GO:0006919| activation of caspase activity SNCA;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ITGB3;PPARA GO:0014070| response to organic cyclic compound CYP1A1;PPARG;PTGS2;CYP1A2 GO:0030855| epithelial cell differentiation PPARG;CBR1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG;MTNR1B;AKT1 GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007165| signal transduction ESR1;AKT1;NR1I3;CSNK2A1;MTNR1A;YARS;NR1I2;PPARG;MTNR1B GO:0001893| maternal placenta development RXRA;AKT1 GO:0007566| embryo implantation RXRA;PTGS2 GO:0019216| regulation of lipid metabolic process PPARA;PPARG;CYP1A1;RXRA;NCOA2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway MTNR1A;APP;MTNR1B;PPARG;AKT1 GO:1905461| PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0032869| cellular response to insulin stimulus AKT1;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG 8052:[DB07863 DB00590] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00590|Doxazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;CYP2C19;CYP2D6;CYP3A4;ORM1;ABCB1;SLC22A1 common genes common pathways GO:0042493| response to drug PPARG;ADRA1A;ABCB1 GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;PPARG;ADRA1A;ADRA1B GO:0042593| glucose homeostasis ADRA1B;PPARG GO:0007165| signal transduction ADRA1B;ADRA1D;PPARG;ADRA1A 8053:[DB07863 DB00333] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00333|Methadone OPRM1;GRIN3A;CHRNA10;OPRD1;HTR3A;LY96;ORM2;CYP3A4;CYP2C19;CYP3A5;CYP3A7;CYP2D6;CYP2B6;CYP2C8;CYP19A1;CYP1A2;CYP2C18;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;PPARG;ABCB1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0045087| innate immune response PPARG;LY96 GO:0010033| response to organic substance CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007165| signal transduction OPRM1;OPRD1;PPARG;CHRNA10;HTR3A GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRD1;OPRM1 8054:[DB07863 DB01348] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure ACE;PPARG 8055:[DB07863 DB09054] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;SLCO1B3;SLCO1B1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug PPARG;ABCG2;ABCB1 8056:[DB07863 DB01565] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0045087| innate immune response TRIM13;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;POMC GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;POMC;OPRM1;OPRD1 GO:0007165| signal transduction POMC;OPRD1;OPRM1;TRIM13;OPRK1;PPARG GO:0042593| glucose homeostasis POMC;PPARG GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0008217| regulation of blood pressure PPARG;POMC 8057:[DB07863 DB14575] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;P2RX4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0008217| regulation of blood pressure PPARG;P2RX4 GO:0010033| response to organic substance UGT1A1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug PPARG;UGT1A1 8058:[DB07863 DB01601] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01601|Lopinavir pol;CYP3A4;CYP2D6;CYP2C19;CYP2B6;CYP2C9;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1B1;ABCB11;SLCO1B3 GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG;CYP2C9 8059:[DB07863 DB00327] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;PTGS1;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;UGT1A9 GO:0007165| signal transduction OPRD1;OPRM1;OPRK1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 8060:[DB07863 DB08439] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0007566| embryo implantation RXRA;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;PTGS2;CYP3A4 GO:0045087| innate immune response PPARG;LTF GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006351| transcription, DNA-dependent LTF;NCOA2;RXRA;PPARG GO:0042493| response to drug PPARG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG;LTF 8061:[DB07863 DB02703] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1;NCOA2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ABCB11;SLCO1B1 GO:0010033| response to organic substance UGT1A1;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0042493| response to drug PPARG;UGT1A1;ABCC2;ABCG2 8062:[DB07863 DB00518] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A1;PPARG;CYP1A2 GO:0033189| response to vitamin A CYP1A1;PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;PPARG GO:0010033| response to organic substance CYP1A2;CYP1A1;PPARG 8063:[DB07863 DB00268] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2D6 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;RXRA;PPARG;NCOA2 GO:0007507| heart development PPARG;RXRA;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;DRD3;RXRA;PPARG GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression DRD2;DRD3;NCOA2 GO:0042493| response to drug PPARG;DRD3;HTR2B;HTR2C;HTR1B;DRD2;HTR2A;CYP1A2;DRD1 GO:0007165| signal transduction PPARG;DRD3;ADRA2A;HTR2C;HTR2B;DRD2;HTR1B;ADRA2C;DRD4;HTR1A;ADRA2B;HTR2A;HTR1D;DRD1;DRD5 GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0042593| glucose homeostasis PPARG;ADRA2A GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;DRD3;RXRA GO:0007186| G-protein coupled receptor signaling pathway DRD3;PPARG;HTR1B;DRD2;ADRA2A;HTR2C;HTR2B;HTR1D;HTR2A;ADRA2B;ADRA2C;HTR1A;DRD4;DRD5;DRD1 GO:0008285| negative regulation of cell proliferation DRD2;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0048511| rhythmic process DRD4;NCOA2;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C;HTR2A GO:0014070| response to organic cyclic compound PPARG;CYP1A2 8064:[DB07863 DB01196] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways GO:0007165| signal transduction PPARG;ESR2;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;PPARG;RXRA;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA;PPARG GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;RXRA;PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;ESR2;RXRA;PPARG;NCOA2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;RXRA;PPARG;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0042493| response to drug PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;NCOA2;RXRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;RXRA;PPARG 8065:[DB07863 DB06263] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0030855| epithelial cell differentiation CBR1;PPARG GO:0007584| response to nutrient PPARG;POR GO:0048511| rhythmic process TOP2A;PPARG;NCOA2 GO:0019395| fatty acid oxidation PPARG;POR GO:0042493| response to drug POR;PPARG GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0043065| positive regulation of apoptotic process PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;RXRA;NCOA2 8066:[DB07863 DB00186] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRA5;GABRP;GABRD;PPARG;GABRB3;GABRQ;GABRB1;GABRE;TSPO;GABRA6 GO:0042493| response to drug GABRG3;TSPO;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0043065| positive regulation of apoptotic process PPARG;TSPO 8067:[DB07863 DB00426] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 8068:[DB07863 DB00753] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0042493| response to drug CYP2E1;GABRG3;MT-ND1;PPARG GO:0007165| signal transduction GRIA1;GABRD;PPARG;GABRP;CHRNB2;GABRA5;GABRB3;CHRNA4;ATP2C1;GABRA6;GABRE;GABRQ;GABRB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CALM1 GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0014070| response to organic cyclic compound MT-ND1;PPARG 8069:[DB07863 DB01140] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways 8070:[DB07863 DB12161] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0042493| response to drug PPARG;CYP1A2 GO:0030855| epithelial cell differentiation PPARG;CBR1 GO:0014070| response to organic cyclic compound PPARG;CYP1A2 GO:0010033| response to organic substance CYP1A2;PPARG 8071:[DB07863 DB08909] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PPARG;CYP3A4;PNLIP 8072:[DB07863 DB01201] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;CYP3A4 8073:[DB07863 DB00688] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00688|Mycophenolate mofetil IMPDH1;IMPDH2;UGT1A1;UGT1A7;UGT1A6;UGT1A9;UGT2B7;UGT1A8;UGT1A10;CES1;CES2;CYP3A4;CYP3A5;CYP2C8;ALB;SLCO1B1;SLCO1B3;ABCC2;ABCG2;ABCB1 common genes common pathways GO:0007623| circadian rhythm IMPDH2;NCOA2 GO:0006629| lipid metabolic process UGT2B7;CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug ABCB1;ABCC2;ABCG2;UGT1A1;PPARG GO:0051289| protein homotetramerization IMPDH2;RXRA GO:0019216| regulation of lipid metabolic process NCOA2;UGT1A9;RXRA;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;NCOA2;UGT1A1 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB;SLCO1B1;SLCO1B3 8074:[DB07863 DB00747] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0007165| signal transduction CHRM4;CHRM3;CHRNB2;PPARG;CHRNA4;CHRM5;CHRM2;CHRM1 GO:0007186| G-protein coupled receptor signaling pathway CHRM4;PPARG;CHRM3;CHRM1;CHRM2;CHRM5 8075:[DB07863 DB04855] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;PPARG;ADRB1;ADRA1A;ADRA2A;KCNK2;ADRA2B;ADRA2C;ADRA1B GO:0007165| signal transduction ADRA2C;ADRA2B;ADRA1B;PPARG;ADRA1D;ADRA2A;ADRB1;ADRA1A GO:0043010| camera-type eye development RXRA;CACNA1C GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA1B;ADRA2A;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;PPARG GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 GO:0007507| heart development CACNA1C;RXRA;PPARG GO:0009612| response to mechanical stimulus PPARG;KCNK2 GO:0009409| response to cold PPARG;ADRB1 GO:0042493| response to drug ABCB1;ADRA1A;PPARG 8076:[DB07863 DB00343] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00343|Diltiazem CACNG1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2D6;CYP2C8;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2D6 8077:[DB07863 DB00844] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0007165| signal transduction PPARG;OPRK1;OPRD1;OPRM1 8078:[DB07863 DB00624] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00624|Testosterone AR;ESR1;NR3C2;CYP3A5;CYP19A1;CYP11A1;MAOA;CYP3A7;CYP3A4;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;AR;ESR1 GO:0035902| response to immobilization stress CYP1A1;PPARG GO:0006629| lipid metabolic process CYP11A1;CYP3A4;CYP2C9;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;ESR1;AR GO:0043065| positive regulation of apoptotic process PPARG;CYP1B1 GO:0006351| transcription, DNA-dependent ESR1;AR;NCOA2;PPARG;RXRA;NR3C2 GO:0043401| steroid hormone mediated signaling pathway NR3C2;RXRA;PPARG;AR;ESR1 GO:0008203| cholesterol metabolic process CYP11A1;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;RXRA GO:0001701| in utero embryonic development RXRA;AR GO:0006367| transcription initiation from RNA polymerase II promoter NR3C2;PPARG;RXRA;AR;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0016032| viral reproduction RXRA;SLC10A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;RXRA;PPARG;NCOA2;NR3C2 GO:0042493| response to drug ABCB1;ABCG2;PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;AR;ESR1 GO:0007165| signal transduction AR;ESR1;NR3C2;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process NCOA2;RXRA;PPARG;CYP1A1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0010033| response to organic substance PPARG;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;AR GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;SLC10A1;RXRA;NCOA2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG 8079:[DB07863 DB00934] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0007623| circadian rhythm NCOA2;HTR7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PPARG;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042493| response to drug HTR2A;CYP1A2;HTR2C;ADRA1A;DRD2;PPARG;SLC6A2 GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;CHRM3;PPARG;ADRA1A;DRD2;HTR7;CHRM4;ADRA2A;HTR2C;CHRM5;HRH1;ADRA2C;CHRM1;CHRM2;HTR2A;ADRA2B;ADRA1B GO:0032870| cellular response to hormone stimulus ADRA2A;NCOA2 GO:0042593| glucose homeostasis ADRA2A;PPARG;ADRA1B GO:0007165| signal transduction ADRA1B;CHRM1;ADRA2C;ADRA2B;HTR2A;CHRM2;CHRM5;HRH1;HTR2C;ADRA2A;ADRA1A;DRD2;CHRM4;HTR7;PPARG;ADRA1D;CHRM3 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;DRD2 8080:[DB07863 DB11386] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11386|Chlorobutanol KCNH2 common genes common pathways 8081:[DB07863 DB14003] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0001890| placenta development TTPA;PPARG;RXRA GO:0008217| regulation of blood pressure CYP4F2;PPARG GO:0007584| response to nutrient PPARG;TTPA GO:0007165| signal transduction PPARG;VLDLR GO:0045893| positive regulation of transcription, DNA-dependent SEC14L2;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA2;SEC14L2 GO:0042493| response to drug PPARG;ABCB1 GO:0016032| viral reproduction RXRA;LDLR;SCARB1 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;LDLR GO:0008203| cholesterol metabolic process APOBR;RXRA;LDLR;VLDLR GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA;SEC14L2 GO:0006629| lipid metabolic process LDLR;TTPA;PPARG;APOBR;VLDLR;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;VLDLR 8082:[DB07863 DB09128] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008285| negative regulation of cell proliferation PPARG;DRD2 GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;HTR2A;ADRA2C;HTR1A;DRD2;PPARG GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0007165| signal transduction PPARG;DRD2;HTR1A;ADRA2C;HTR2A;ADRA1B GO:0042493| response to drug DRD2;PPARG;HTR2A GO:0016032| viral reproduction HTR2A;RXRA GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;RXRA;PPARG;NCOA2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PPARG 8083:[DB07863 DB11642] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007165| signal transduction HRH3;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;HRH3 GO:0042493| response to drug PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARG;CYP2D6 GO:0035902| response to immobilization stress PPARG;CYP1A2 8084:[DB07863 DB07177] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 8085:[DB07863 DB03793] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0042593| glucose homeostasis PPARG;SLC16A1 GO:0015721| bile acid and bile salt transport SLCO2B1;RXRA;NCOA2 GO:0006629| lipid metabolic process PPARG;SLC16A1 8086:[DB07863 DB02925] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB02925|Piretanide SLC12A1 common genes common pathways 8087:[DB07863 DB00603] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007165| signal transduction ESR1;PGR;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;RXRA;PPARG;PGR GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;PGR;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006351| transcription, DNA-dependent PGR;RXRA;PPARG;NCOA2;ESR1 GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;PGR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;RXRA;ESR1 GO:0006629| lipid metabolic process CYP3A4;PPARG;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RXRA;PPARG;NCOA2;PGR 8088:[DB07863 DB06480] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;NCOA2;RXRA GO:0007165| signal transduction HTR4;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;HTR4 8089:[DB07863 DB00472] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00472|Fluoxetine SLC6A4;KCNH2;HTR2C;CKS1B;CHRNA2;CHRNA3;CHRNB4;CYP2C19;CYP2D6;CYP2C9;CYP2B;CYP1A2;CYP3A4;CYP2B6;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;HTR2C;PPARG;SLC6A4;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent CKS1B;RXRA;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent CKS1B;RXRA;PPARG GO:0007623| circadian rhythm NCOA2;SLC6A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;PPARG;CYP2D6 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0007584| response to nutrient SLC6A4;PPARG GO:0010033| response to organic substance PPARG;SLC6A4;CYP1A2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0007186| G-protein coupled receptor signaling pathway HTR2C;PPARG GO:0007165| signal transduction CHRNA3;HTR2C;CHRNB4;PPARG;CHRNA2 8090:[DB07863 DB01250] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01250|Olsalazine TPMT;IFNG common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;NCOA2;RXRA;PPARG GO:0045892| negative regulation of transcription, DNA-dependent IFNG;PPARG;NCOA2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IFNG 8091:[DB07863 DB00881] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0008217| regulation of blood pressure ACE;PPARG 8092:[DB07863 DB06403] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0007165| signal transduction EDNRA;PPARG;EDNRB GO:0007186| G-protein coupled receptor signaling pathway EDNRB;PPARG;EDNRA GO:0019216| regulation of lipid metabolic process NCOA2;UGT1A9;RXRA;PPARG GO:0008217| regulation of blood pressure EDNRA;PPARG;EDNRB GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;RXRA;NCOA2 GO:0014070| response to organic cyclic compound PPARG;EDNRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDNRB;RXRA;PPARG;NCOA2 GO:0007507| heart development PPARG;EDNRA;RXRA GO:0006629| lipid metabolic process PPARG;CYP3A4;UGT2B7 GO:0001701| in utero embryonic development RXRA;EDNRA GO:0042493| response to drug PPARG;ABCB1 8093:[DB07863 DB01333] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 8094:[DB07863 DB01339] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways GO:0007165| signal transduction PPARG;CHRNA2 GO:0042493| response to drug ABCB1;PPARG 8095:[DB07863 DB13857] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0007165| signal transduction PPARG;PGR GO:0006355| regulation of transcription, DNA-dependent PGR;RXRA;PPARG;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;PGR GO:0006351| transcription, DNA-dependent PGR;NCOA2;PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;PGR GO:0006629| lipid metabolic process PPARG;CYP3A4 8096:[DB07863 DB00909] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00909|Zonisamide SCN1A;SCN2A;SCN3A;SCN4A;SCN5A;SCN9A;SCN11A;SCN1B;SCN2B;SCN3B;SCN4B;CACNA1G;CACNA1H;CACNA1I;CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA8;CA9;CA10;CA11;CA12;CA13;CA14;MAOB;MAOA;CYP3A4;AOX1;CYP2C19;UGT1A1;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug UGT1A1;MAOB;PPARG;SCN11A;CA9 GO:0031100| organ regeneration UGT1A1;PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1;NCOA2 GO:0007165| signal transduction PPARG;CACNA1I GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010033| response to organic substance UGT1A1;PPARG;CA2 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 8097:[DB07863 DB00222] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0007165| signal transduction PPARG;ABCC8 GO:0015721| bile acid and bile salt transport ABCB11;NCOA2;RXRA GO:0006629| lipid metabolic process PPARG;CYP2C9 GO:0042493| response to drug PPARG;ABCC8;KCNJ11 GO:0016525| negative regulation of angiogenesis PPARG;ABCC8 8098:[DB07863 DB00721] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0043065| positive regulation of apoptotic process KCNMA1;PPARG GO:0042493| response to drug BCHE;MAOB;PPARG;SLC6A3 GO:0007165| signal transduction PPARG;HTR3A;CHRNA2 GO:0014070| response to organic cyclic compound PPARG;SLC6A3 GO:0007584| response to nutrient BCHE;PPARG GO:0008285| negative regulation of cell proliferation BCHE;PPARG 8099:[DB07863 DB00273] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00273|Topiramate GABRA1;SCN1A;GRIK1;CA2;CA4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CA1;CA3;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0010033| response to organic substance PPARG;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0007165| signal transduction GABRB3;GABRB1;GABRQ;GABRE;GABRA6;GABRA5;GABRP;PPARG;GABRD 8100:[DB07863 DB14507] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007623| circadian rhythm GSK3B;NCOA2 GO:0048511| rhythmic process NCOA2;PPARG;GSK3B GO:0007165| signal transduction PPARG;IMPA2;IMPA1 8101:[DB07863 DB00996] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GABBR1;ADORA1;PPARG;GABBR2 GO:0007165| signal transduction PPARG;ADORA1;GABBR2;GABBR1 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0008217| regulation of blood pressure PPARG;CACNA1B GO:0008285| negative regulation of cell proliferation PPARG;ADORA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;GRIN1 GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042493| response to drug GRIN2A;PPARG 8102:[DB07863 DB06637] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG GO:0009612| response to mechanical stimulus PPARG;KCNA5 GO:0045475| locomotor rhythm NCOA2;KCND2 GO:0014070| response to organic cyclic compound PPARG;KCNC2 GO:0010033| response to organic substance PPARG;KCNA5 GO:0042593| glucose homeostasis PPARG;KCNB1 8103:[DB07863 DB06207] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;ADRA1A;PPARG;ADRA1D GO:0019216| regulation of lipid metabolic process RXRA;PPARG;NCOA2;ABCB4 GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0007165| signal transduction ADRA1A;ADRA1D;PPARG;ADRA1B GO:0014070| response to organic cyclic compound ABCB4;PPARG GO:0055088| lipid homeostasis PPARG;ABCB4 GO:0001890| placenta development ABCB4;RXRA;PPARG GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A GO:0010033| response to organic substance PPARG;ABCB4 GO:0007623| circadian rhythm NCOA2;ABCB4 GO:0006629| lipid metabolic process CYP3A4;ABCB4;UGT2B7;PPARG GO:0042493| response to drug ABCB4;ABCB1;ADRA1A;PPARG GO:0033189| response to vitamin A ABCB4;PPARG 8104:[DB07863 DB01259] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;EGFR GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0007507| heart development PPARG;RXRA;ERBB2 GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;RXRA;PPARG;EGFR GO:0007623| circadian rhythm NCOA2;EGFR GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;ERBB2 GO:0016032| viral reproduction RXRA;TAP1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;EGFR GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2;ERBB2 GO:0042493| response to drug ABCB1;PPARG GO:0033993| response to lipid EGFR;PPARG GO:0007165| signal transduction ERBB2;PPARG;EGFR GO:0014070| response to organic cyclic compound EGFR;PPARG 8105:[DB07863 DB01406] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;PPARG;RXRA;PGR GO:0006351| transcription, DNA-dependent ESR1;AR;RXRA;PPARG;NCOA2;PGR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG;RXRA GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;RXRA;NCOA2;PGR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;AR;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;PPARG;RXRA;NCOA2;PGR GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;PPARG;RXRA;AR;ESR1 GO:0001701| in utero embryonic development AR;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0030522| intracellular receptor mediated signaling pathway AR;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CCL2;GNRHR2;GNRHR GO:0007165| signal transduction ESR1;AR;CCL2;PPARG;GNRHR2;PGR;GNRHR GO:0008285| negative regulation of cell proliferation AR;PPARG GO:0043627| response to estrogen stimulus PPARG;ESR1 8106:[DB07863 DB00862] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0007165| signal transduction PPARG;PDE5A GO:0042493| response to drug PPARG;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PPARG 8107:[DB07863 DB01215] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRA5;GABRR2;GABRP;PPARG;GABRD;GABRB3;GABRB1;GABRQ;GABRE;GABRA6 GO:0042493| response to drug GABRG3;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 8108:[DB07863 DB00448] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;RXRA GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1 GO:0010033| response to organic substance CYP1A1;PPARG GO:0006919| activation of caspase activity MAPT;PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A1 GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG GO:0033189| response to vitamin A CYP1A1;PPARG GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;PPARG 8109:[DB07863 DB01181] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1I2 GO:0030522| intracellular receptor mediated signaling pathway NCOA2;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;RXRA;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;NR1I2 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PPARG;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;NR1I2;PPARG GO:0006351| transcription, DNA-dependent PPARG;RXRA;NR1I2;NCOA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;RXRA GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;NR1I2;PPARG GO:0008217| regulation of blood pressure PTGS1;PPARG GO:0007165| signal transduction PPARG;NR1I2 8110:[DB07863 DB13170] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB13170|Plecanatide GUCY1A2 common genes common pathways GO:0007165| signal transduction PPARG;GUCY1A2 8111:[DB07863 DB01073] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0016032| viral reproduction POLA1;RXRA 8112:[DB07863 DB00436] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;KCNMA1 GO:0010033| response to organic substance PPARG;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG 8113:[DB07863 DB00484] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;PPARG;ADRA2B;ADRA2C GO:0042593| glucose homeostasis ADRA2A;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;ADRA2A GO:0007165| signal transduction ADRA2C;ADRA2B;PPARG;ADRA2A 8114:[DB07863 DB05207] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;TNF;PPARG;NCOA2 GO:0043065| positive regulation of apoptotic process PPARG;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;RXRA;PPARG;NCOA2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;TNF;PPARG GO:0010033| response to organic substance PPARG;TNF GO:0006919| activation of caspase activity TNF;PPARG GO:0007165| signal transduction IL1R1;PPARG GO:0045994| positive regulation of translational initiation by iron RXRA;TNF 8115:[DB07863 DB11737] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0033993| response to lipid PPARG;EGFR GO:0007165| signal transduction PPARG;EGFR GO:0014070| response to organic cyclic compound PPARG;EGFR;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0007623| circadian rhythm NCOA2;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP1A2;CYP3A4 GO:0035902| response to immobilization stress PPARG;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG;RXRA GO:0042493| response to drug CYP1A2;PPARG 8116:[DB07863 DB01225] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways GO:0007584| response to nutrient SERPINC1;PPARG GO:0009612| response to mechanical stimulus PPARG;MPO 8117:[DB07863 DB01020] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways GO:0007165| signal transduction GUCY1A2;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG 8118:[DB07863 DB01065] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PPARG;CYP2C9 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;CALR;NCOA2;ESR1 GO:0009612| response to mechanical stimulus MPO;PPARG GO:0071300| cellular response to retinoic acid RORB;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RXRA;PPARG;NCOA2;RORB GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;PPARG GO:0006351| transcription, DNA-dependent ESR1;NCOA2;RXRA;PPARG;RORB GO:0043401| steroid hormone mediated signaling pathway RORB;PPARG;RXRA;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ESR1 GO:0007623| circadian rhythm MTNR1A;NCOA2;MTNR1B GO:0033189| response to vitamin A PPARG;CYP1A1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0042752| regulation of circadian rhythm PPARG;RORB GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;RORB;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0030522| intracellular receptor mediated signaling pathway RORB;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;RXRA;PPARG;RORB GO:0006355| regulation of transcription, DNA-dependent RORB;RXRA;CALR;PPARG;NCOA2;ESR1 GO:0042493| response to drug CYP1A2;PPARG;CYP1A1;CALR GO:0007165| signal transduction MTNR1A;MTNR1B;PPARG;ESR1 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0042593| glucose homeostasis MTNR1B;PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;NCOA2 GO:0007186| G-protein coupled receptor signaling pathway CALM1;PPARG;MTNR1B;MTNR1A GO:0045892| negative regulation of transcription, DNA-dependent CALR;PPARG;NCOA2;RORB GO:0010033| response to organic substance CYP1A2;PPARG;CYP1A1;CALR GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1 GO:0048511| rhythmic process PPARG;NCOA2;RORB GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;CYP1A2 8119:[DB07863 DB06681] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB06681|Belatacept CD86;CD80 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;RXRA;PPARG;CD86 GO:0016032| viral reproduction CD80;RXRA;CD86 GO:0007165| signal transduction PPARG;CD86 8120:[DB07863 DB01535] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;OPRK1;PPARG 8121:[DB07863 DB00679] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0042493| response to drug DRD1;HTR2A;CYP2E1;ADRA1A;DRD2;PPARG GO:0016032| viral reproduction RXRA;HTR2A GO:0032922| circadian regulation of gene expression NCOA2;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;NCOA2;PPARG;RXRA GO:0006629| lipid metabolic process PPARG;CYP2D6 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PPARG GO:0007186| G-protein coupled receptor signaling pathway DRD1;ADRA1B;HTR2A;ADRA1A;DRD2;PPARG GO:0042593| glucose homeostasis PPARG;ADRA1B GO:0007165| signal transduction DRD1;ADRA1B;HTR2A;ADRA1A;DRD2;PPARG 8122:[DB07863 DB00280] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0045475| locomotor rhythm NCOA2;KCND2 GO:0010033| response to organic substance PPARG;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway CHRM1;CHRM2;CHRM3;PPARG GO:0007165| signal transduction PPARG;CHRM3;CHRM2;CHRM1 GO:0042493| response to drug CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process PPARG;CYP1A2;CYP3A4 8123:[DB07863 DB01381] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0042493| response to drug SLC6A2;PPARG GO:0006629| lipid metabolic process PLA2G2A;PPARG;CYP2C9 8124:[DB07863 DB01208] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;RXRA;NCOA2 GO:0006629| lipid metabolic process CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0042493| response to drug PPARG;ABCC2;ABCB1;CYP1A2 GO:0032870| cellular response to hormone stimulus NCOA2;ABCC2 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0048511| rhythmic process NCOA2;TOP2A;PPARG GO:0010033| response to organic substance CYP1A2;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PPARG 8125:[DB07863 DB01166] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0007165| signal transduction PPARG;PDE3A GO:0007186| G-protein coupled receptor signaling pathway PDE3A;PPARG GO:0010033| response to organic substance PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP2D6;PPARG;PDE3A;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;PDE3A;PPARG 8126:[DB07863 DB05311] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB05311|Ecallantide KLKB1 common genes common pathways 8127:[DB07863 DB01241] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:0007507| heart development PPARG;RXRA;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;RXRA;PPARG;NCOA2 GO:0035902| response to immobilization stress CYP1A2;PPARG GO:0006629| lipid metabolic process CYP1A2;PPARA;CYP3A4;PPARG;CYP2C9 GO:0042594| response to starvation UGT1A1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;NCOA2;PPARG;RXRA GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;PPARA GO:0043401| steroid hormone mediated signaling pathway PPARA;RXRA;PPARG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;PPARA GO:0032922| circadian regulation of gene expression NCOA2;PPARA GO:0030522| intracellular receptor mediated signaling pathway PPARA;NCOA2 GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;RXRA;PPARG;NCOA2 GO:0042493| response to drug CYP1A2;UGT1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;PPARA GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;RXRA;PPARA GO:0048511| rhythmic process NCOA2;PPARG;PPARA GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;CYP1A2 GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0015721| bile acid and bile salt transport RXRA;NCOA2;SLCO1B1 GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;PPARG 8128:[DB07863 DB00778] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways GO:0042493| response to drug ABCB1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 8129:[DB07863 DB00181] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GABBR1;GABBR2;PPARG GO:0007165| signal transduction GABBR1;GABBR2;PPARG 8130:[DB07863 DB04839] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0030522| intracellular receptor mediated signaling pathway NCOA2;AR GO:0016525| negative regulation of angiogenesis PPARG;KLK3 GO:0001701| in utero embryonic development RXRA;AR GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;PPARG;RXRA;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;AR GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;NCOA2;AR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;AR GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG;AR GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;AR GO:0008285| negative regulation of cell proliferation PPARG;AR GO:0007165| signal transduction PPARG;AR 8131:[DB07863 DB01276] DB07863|2-chloro-5-nitro-N-phenylbenzamide NCOA2;PPARG;RXRA DB01276|Exenatide GLP1R;ALB common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;RXRA;ALB GO:0007165| signal transduction GLP1R;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GLP1R 8132:[DB01183 DB07543] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;ADRB2;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB2;OPRM1;OPRD1 GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 8133:[DB01183 DB03685] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways GO:0051607| defense response to virus OPRK1;ISG20 GO:0016032| viral reproduction UCKL1;CREB1 GO:0042060| wound healing OPRM1;B4GALT1 GO:0043065| positive regulation of apoptotic process B4GALT1;CREB1 GO:0008152| metabolic process UGT1A1;UCKL1;CES1 GO:0045087| innate immune response TLR4;ISG20 GO:0030879| mammary gland development CREB1;B4GALT1 GO:0008285| negative regulation of cell proliferation B4GALT1;OPRM1 GO:0002376| immune system process TLR4;ISG20 GO:0002064| epithelial cell development B4GALT1;ESR1 8134:[DB01183 DB07926] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07926|N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE MMP1 common genes common pathways GO:0016032| viral reproduction CREB1;MMP1 GO:0044267| cellular protein metabolic process MMP1;ALB 8135:[DB01183 DB01179] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB;TUBA4A GO:0048511| rhythmic process TOP2A;CREB1 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TOP2A;CREB1;TLR4 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0002576| platelet degranulation TUBA4A;ALB 8136:[DB01183 DB05127] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05127|ANA971 TLR7 common genes common pathways GO:0050729| positive regulation of inflammatory response TLR7;TLR4 GO:0002224| toll-like receptor signaling pathway TLR4;TLR7 GO:0045359| positive regulation of interferon-beta biosynthetic process TLR7;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR7;TLR4 GO:0032757| positive regulation of interleukin-8 production TLR7;TLR4 GO:0002376| immune system process TLR7;TLR4 GO:0032722| positive regulation of chemokine production TLR7;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR7;TLR4;CREB1;OPRK1 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR7;TLR4 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR4;TLR7 GO:0071260| cellular response to mechanical stimulus TLR7;TLR4 GO:0045087| innate immune response TLR7;TLR4 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TLR7 GO:0051607| defense response to virus OPRK1;TLR7 GO:0007252| I-kappaB phosphorylation TLR7;TLR4 GO:0006955| immune response OPRD1;TLR4;TLR7;OPRK1 GO:0006954| inflammatory response TLR7;TLR4 8137:[DB01183 DB03372] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;IL2;OPRM1;OPRD1 GO:0050729| positive regulation of inflammatory response IL2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration IL2;ESR1;OPRM1 GO:0002376| immune system process IL2;TLR4 GO:0030890| positive regulation of B cell proliferation TLR4;IL2 GO:0032729| positive regulation of interferon-gamma production TLR4;IL2 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;IL2 GO:0043066| negative regulation of apoptotic process ALB;IL2 GO:0006955| immune response OPRD1;TLR4;IL2;OPRK1 8138:[DB01183 DB01594] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0009636| response to toxin GABRB1;CES1 GO:0006811| ion transport GABRA5;GABRA3;GABRG1;GABRR2;GABRP;GABRD;GABRB2;GABRA2;GABRG2;GABRB1;SLCO1A2;GABRE;GABRA1;GABRR1;GABRR3;GABRG3;GABRB3 GO:0006810| transport GABRA1;GABRR1;GABRB1;GABRG2;GABRB3;GABRD;GABRB2;GABRA5;GABRA3;GABRR2;ABCB1 GO:0007165| signal transduction OPRK1;GABRP;TLR4;CREB1;GABRD;GABRA5;GABRR2;GABRB3;ESR1;OPRD1;GABRB1;OPRM1;GABRE GO:0042493| response to drug GABRG3;ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission GABRB2;GABRD;GABRR2;GABRG1;GABRA5;OPRK1;GABRR1;OPRM1;OPRD1;GABRG2;GABRR3 GO:1901215| GABRB3;CREB1;GABRB2 8139:[DB01183 DB00645] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00645|Dyclonine SCN10A common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCB1;SCN10A GO:0006811| ion transport SLCO1A2;SCN10A GO:0019233| sensory perception of pain SCN10A;OPRK1;OPRM1;OPRD1 GO:0007600| sensory perception OPRM1;SCN10A;OPRK1 8140:[DB01183 DB04863] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0002576| platelet degranulation ITGB3;ALB;ITGA2B GO:0042060| wound healing ITGB3;OPRM1 GO:0016032| viral reproduction CREB1;ITGB3 8141:[DB01183 DB01580] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0007568| aging CREB1;ADRB3 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;ADRB3;OPRK1;ADRB1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ADRB3;ADRB1;ADRB2;ESR1;OPRD1;OPRM1 GO:0015711| organic anion transport SLC22A2;SLCO1A2 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC22A2 GO:0006811| ion transport SLC22A2;SLCO1A2 GO:0042755| eating behavior OPRK1;ADRB3;OPRM1;OPRD1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;ADRB3 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:1904646| TLR4;ADRB2 8142:[DB01183 DB00725] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway CHRM5;OPRM1;OPRD1;CHRM1;CHRM2;CHRM4;OPRK1;CHRM3 GO:0007165| signal transduction CHRM2;CHRM1;ESR1;OPRD1;OPRM1;CHRM5;OPRK1;CHRM4;TLR4;CREB1;CHRM3 8143:[DB01183 DB00838] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00838|Clocortolone NR3C1 common genes common pathways GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;NR3C1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;NR3C1;OPRD1;OPRM1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;CREB1;TLR4 8144:[DB01183 DB06935] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 8145:[DB01183 DB01833] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01833|L-2-Amino-4-(Guanidinooxy)Butyric Acid NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 8146:[DB01183 DB00087] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;CD52 GO:0007165| signal transduction FCGR2B;CREB1;TLR4;FCGR1A;OPRK1;ESR1;OPRM1;FCGR2C;OPRD1 GO:0006898| receptor-mediated endocytosis FCGR1A;ALB;FCGR2B GO:0002376| immune system process C1QA;C1QC;FCGR2A;FCGR1A;C1QB;C1R;TLR4 GO:1904646| TLR4;FCGR2B GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0045087| innate immune response TLR4;C1QB;C1R;FCGR1A;C1QC;C1QA GO:0009617| response to bacterium FCGR2B;TLR4 GO:0016032| viral reproduction CREB1;FCGR2B GO:0006955| immune response FCGR1A;OPRK1;C1R;FCGR3B;FCGR2B;TLR4;FCGR3A;FCGR2C;OPRD1;C1QC GO:0006954| inflammatory response FCGR2B;TLR4 8147:[DB01183 DB08128] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08128|(1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine PNMT common genes common pathways 8148:[DB01183 DB06981] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06981|(2S)-2-(1H-indol-3-yl)pentanoic acid SKP1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle SKP1;ABCB1 GO:0043687| post-translational protein modification ALB;SKP1 8149:[DB01183 DB06803] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP2C9;CYP1A2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2C8;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CES1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;TLR4;UGT1A1 GO:0042737| drug catabolic process CYP2C9;CYP3A4;CYP1A2 8150:[DB01183 DB06914] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;TLR4 GO:0043065| positive regulation of apoptotic process HMOX1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;HMOX1;CYP2C8 GO:0035094| response to nicotine CREB1;HMOX1 GO:0071456| cellular response to hypoxia OPRD1;HMOX1 GO:0042167| heme catabolic process HMOX1;UGT1A1 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity HMOX1;ESR1 GO:0043627| response to estrogen stimulus ESR1;HMOX1;OPRK1 GO:0001666| response to hypoxia CREB1;HMOX1 8151:[DB01183 DB00940] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00940|Methantheline CHRM1;HRH2 common genes common pathways GO:0008542| visual learning HRH2;CREB1 GO:0006955| immune response TLR4;OPRK1;HRH2;OPRD1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;HRH2;ESR1;CHRM1;OPRD1;OPRM1 GO:0007613| memory HRH2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway HRH2;CHRM1;OPRD1;OPRM1;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;HRH2 8152:[DB01183 DB01837] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01837|O-acetyl-L-serine PTGS1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;PTGS1 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;CYP2C8 GO:0006954| inflammatory response TLR4;PTGS1 GO:0098869| ALB;PTGS1 8153:[DB01183 DB05943] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05943|Resatorvid CSF2RB;IL2RG common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CSF2RB;OPRM1 GO:0016032| viral reproduction IL2RG;CREB1 GO:0006955| immune response TLR4;OPRK1;IL2RG;OPRD1 GO:0007165| signal transduction CSF2RB;CREB1;TLR4;OPRK1;OPRM1;OPRD1;IL2RG;ESR1 GO:0044267| cellular protein metabolic process ALB;CSF2RB 8154:[DB01183 DB09422] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09422|Soybean oil PPARA common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARA GO:0006351| transcription, DNA-dependent ESR1;PPARA;CREB1 GO:0042060| wound healing PPARA;OPRM1 GO:0006629| lipid metabolic process PPARA;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARA;TLR4;CREB1 GO:1901215| CREB1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARA;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARA;ESR1;CREB1 GO:0042752| regulation of circadian rhythm CREB1;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARA GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0048511| rhythmic process PPARA;CREB1 GO:0001666| response to hypoxia PPARA;CREB1 8155:[DB01183 DB00098] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways GO:0007165| signal transduction OPRM1;CD4;OPRD1;ESR1;ITGAL;CD86;OPRK1;MR1;FCGR2B;CREB1;TLR4 GO:0070588| calcium ion transmembrane transport OPRM1;ITGAV GO:0002376| immune system process CD4;CD1A;CD86;MR1;TLR4 GO:0006898| receptor-mediated endocytosis ALB;FCGR2B GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;ITGAV GO:0032355| response to estradiol stimulus CD4;ESR1 GO:1904646| FCGR2B;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CD4;OPRM1 GO:0007179| transforming growth factor beta receptor signaling pathway ITGB1;CREB1 GO:0045087| innate immune response TLR4;MR1 GO:0050829| defense response to Gram-negative bacterium TLR4;MR1;CD4 GO:0043065| positive regulation of apoptotic process ITGB1;CREB1 GO:0002576| platelet degranulation ALB;ITGB3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CD4 GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0042060| wound healing ITGB3;OPRM1 GO:0051924| regulation of calcium ion transport OPRD1;CD4 GO:0008542| visual learning ITGB1;CREB1 GO:0006954| inflammatory response FCGR2B;TLR4;ITGAL GO:0006955| immune response MR1;TLR4;FCGR2B;CD1A;CD86;OPRK1;OPRD1;CD4 GO:0016032| viral reproduction CD86;ITGB3;FCGR2B;CREB1;ITGB1;ITGAV;CD4 GO:0009617| response to bacterium FCGR2B;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CD4;ESR1;CREB1;CD86 8156:[DB01183 DB03245] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;GCDH GO:0055114| oxidation-reduction process CYP3A4;GCDH;CYP2C8 8157:[DB01183 DB00816] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00816|Orciprenaline ADRB2 common genes common pathways GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0007165| signal transduction ADRB2;ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 8158:[DB01183 DB01983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01983|2(S)-Amino-6-Boronohexanoic Acid ARG1 common genes common pathways GO:0007568| aging CREB1;ARG1 GO:0002376| immune system process ARG1;TLR4 GO:0048545| response to steroid hormone stimulus ARG1;UGT1A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ARG1;OPRM1 GO:0001889| liver development UGT1A1;ARG1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;CREB1 GO:0045087| innate immune response ARG1;TLR4 GO:0042493| response to drug ARG1;UGT1A1;CREB1;ABCB1 8159:[DB01183 DB04185] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04185|Norvaline OTC;GATM common genes common pathways GO:0032868| response to insulin stimulus OTC;OPRK1 GO:0042493| response to drug OTC;CREB1;UGT1A1;ABCB1 GO:0001889| liver development UGT1A1;OTC 8160:[DB01183 DB08962] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08962|Glibornuride CYP2C9 common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4;CES1 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 8161:[DB01183 DB01165] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0033762| response to glucagon stimulus ABCC2;CREB1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ABCC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TOP2A;TLR4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ABCC2;OPRM1;CYP1A2 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;ABCC1;UGT1A1;ABCC2;ABCB1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0015711| organic anion transport SLC22A6;SLC22A5;SLC22A4;SLCO1A2 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006810| transport ABCC2;ABCB1;ABCC1;ABCB11 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLCO1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0043627| response to estrogen stimulus ABCC2;OPRK1;ESR1 GO:0048511| rhythmic process CREB1;TOP2A GO:0015721| bile acid and bile salt transport ALB;ABCB11;SLCO1A2 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1;SLC22A5 GO:0055085| transmembrane transport ABCC2;ABCB1;ABCC1;SLC22A6;SLC22A5;ABCB11;SLC22A4;SLCO1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0006811| ion transport SLC22A4;SLCO1A2;SLC22A5 8162:[DB01183 DB00671] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 GO:0015711| organic anion transport SLCO1A2;SLC22A5 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0006811| ion transport SLCO1A2;SLC22A5;SLC15A2;SLC15A1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLCO1A2;SLC15A2;SLC22A5 8163:[DB01183 DB01959] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways GO:0032729| positive regulation of interferon-gamma production PDE4D;PDE4B;TLR4 GO:0071222| cellular response to lipopolysaccharide PDE4D;TLR4;OPRK1;PDE4B GO:0007568| aging PDE4D;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;PDE4D;OPRM1;OPRK1;PDE4B GO:0007165| signal transduction CREB1;TLR4;PDE4B;OPRK1;ESR1;OPRM1;PDE4D;OPRD1 8164:[DB01183 DB01618] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0007626| locomotory behavior OPRM1;DRD2;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TLR4;CREB1;ESR1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0045471| response to ethanol OPRM1;OPRK1;DRD2;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0019233| sensory perception of pain OPRK1;HTR2A;OPRD1;OPRM1 GO:0016032| viral reproduction CREB1;HTR2A GO:0008542| visual learning DRD2;CREB1 GO:0043278| response to morphine OPRM1;OPRK1;DRD2 GO:0035094| response to nicotine DRD2;CREB1 GO:0007268| synaptic transmission HTR2A;OPRM1;OPRD1;OPRK1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;DRD2;HTR2A GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:1900273| DRD2;CREB1 GO:0007610| behavior OPRK1;HTR1A;HTR2A GO:0007165| signal transduction TLR4;CREB1;DRD2;OPRK1;OPRD1;OPRM1;HTR2A;CHRM1;ESR1;HTR1A GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CHRM1;HTR1A;HTR2A;DRD2;OPRK1 GO:0007613| memory HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007568| aging CREB1;HTR2A GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0001666| response to hypoxia DRD2;CREB1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0007409| axonogenesis CREB1;DRD2 GO:0009636| response to toxin CES1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;DRD2;TLR4 GO:0042220| response to cocaine DRD2;OPRK1;OPRM1 8165:[DB01183 DB07546] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways GO:0006468| protein phosphorylation CSNK2A2;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CSNK2A2;CREB1 GO:0006351| transcription, DNA-dependent ESR1;CSNK2A2;CREB1 8166:[DB01183 DB05111] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05111|Fontolizumab IFNG common genes common pathways GO:0000060| protein import into nucleus, translocation OPRD1;IFNG GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;ESR1 GO:0045672| positive regulation of osteoclast differentiation CREB1;IFNG GO:0051607| defense response to virus OPRK1;IFNG GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1;IFNG GO:0006955| immune response OPRD1;IFNG;TLR4;OPRK1 GO:0032700| negative regulation of interleukin-17 production TLR4;IFNG GO:0032735| positive regulation of interleukin-12 production IFNG;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1;IFNG GO:0010628| positive regulation of gene expression IFNG;TLR4 8167:[DB01183 DB03600] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes ALB common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;PPARG;TLR4 GO:0002576| platelet degranulation ALB GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0043066| negative regulation of apoptotic process ALB GO:0045087| innate immune response PPARG;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0042493| response to drug PPARG;CREB1;UGT1A1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0043687| post-translational protein modification ALB GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0042752| regulation of circadian rhythm CREB1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0031100| organ regeneration UGT1A1;PPARG GO:0098869| ALB GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;PPARG;TLR4;OPRK1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB;FURIN GO:0007179| transforming growth factor beta receptor signaling pathway FURIN;CREB1 GO:0001895| retina homeostasis ALB GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0048511| rhythmic process CREB1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;PPARG 8168:[DB01183 DB01436] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;CYP27B1;UGT1A1;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA GO:0006351| transcription, DNA-dependent ESR1;VDR;CREB1;RXRA GO:0043401| steroid hormone mediated signaling pathway RXRA;VDR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;VDR;TLR4;RXRA;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;ESR1;VDR GO:0060745| mammary gland branching involved in pregnancy ESR1;VDR GO:0006355| regulation of transcription, DNA-dependent ESR1;VDR;CREB1;RXRA GO:0045893| positive regulation of transcription, DNA-dependent CREB1;RXRA;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP27B1;CYP2C8 GO:0016032| viral reproduction CREB1;RXRA GO:0007595| lactation VDR;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;VDR;RXRA GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;VDR GO:0036378| CYP3A4;CYP27B1 GO:0015721| bile acid and bile salt transport SLCO1A2;RXRA;ALB GO:0010628| positive regulation of gene expression TLR4;VDR GO:0042359| vitamin D metabolic process CYP3A4;CYP27B1;GC GO:0043627| response to estrogen stimulus ESR1;CYP27B1;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;CYP27B1;VDR 8169:[DB01183 DB00866] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRB1;OPRK1;ADRB3;OPRD1;OPRM1;ADRB2;HTR1A GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007568| aging CREB1;ADRB3 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction OPRD1;OPRM1;ADRB2;ESR1;HTR1A;TLR4;CREB1;ADRB1;OPRK1;ADRB3 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007610| behavior HTR1A;OPRK1 GO:0042755| eating behavior ADRB3;OPRK1;OPRD1;OPRM1 GO:1904646| ADRB2;TLR4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;ADRB3 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4;CES1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 8170:[DB01183 DB08256] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways GO:0010628| positive regulation of gene expression TLR4;EPHX2 GO:0009636| response to toxin CES1;EPHX2 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;EPHX2 GO:0006954| inflammatory response EPHX2;TLR4 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0008152| metabolic process EPHX2;CES1;UGT1A1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;EPHX2;CYP2C8 8171:[DB01183 DB02563] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02563|Hexanoyl-CoA ECHS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ECHS1 GO:0008152| metabolic process ECHS1;UGT1A1;CES1 8172:[DB01183 DB06233] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06233|Ridaforolimus MTOR;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0042060| wound healing OPRM1;MTOR GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046889| positive regulation of lipid biosynthetic process MTOR;CREB1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008361| regulation of cell size MTOR;CREB1 GO:0043278| response to morphine OPRM1;OPRK1;MTOR GO:0008542| visual learning MTOR;CREB1 GO:0006468| protein phosphorylation MTOR;CREB1 GO:0071456| cellular response to hypoxia OPRD1;MTOR GO:0009267| cellular response to starvation MTOR;ALB GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;MTOR;TLR4;CREB1;OPRK1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;MTOR;TLR4 GO:0032868| response to insulin stimulus OPRK1;MTOR GO:0036378| CYP3A4 GO:0050769| positive regulation of neurogenesis MTOR;OPRM1 GO:0042220| response to cocaine OPRK1;MTOR;OPRM1 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007584| response to nutrient UGT1A1;MTOR GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression MTOR;TLR4 8173:[DB01183 DB07830] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 8174:[DB01183 DB11785] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11785|Anisodamine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 8175:[DB01183 DB12450] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12450|Propyl Gallate ESR1 common genes ESR1 common pathways GO:0060065| uterus development ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 8176:[DB01183 DB05258] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05258|Natural alpha interferon IFNAR1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;IFNAR1;TLR4;UGT1A1 8177:[DB01183 DB08936] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08936|Chlorcyclizine HRH1 common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;HRH1;OPRD1;OPRM1 GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;HRH1;OPRM1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HRH1;ESR1;OPRK1 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response HRH1;TLR4 8178:[DB01183 DB09160] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:1901529| ABCB1 8179:[DB01183 DB12872] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ADAMTS13 GO:0002576| platelet degranulation ALB;F8 GO:0071560| cellular response to transforming growth factor beta stimulus COL1A1;CREB1 GO:0071260| cellular response to mechanical stimulus TLR4;COL1A1 GO:0042060| wound healing OPRM1;COL1A1 GO:0006953| acute-phase response UGT1A1;F8 GO:0042493| response to drug COL1A1;ABCB1;CREB1;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;COL1A1;ESR1 GO:0055114| oxidation-reduction process CYP3A4;F8;CYP2C8 GO:0048545| response to steroid hormone stimulus COL1A1;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;COL1A1 GO:0007584| response to nutrient UGT1A1;COL1A1 GO:0009636| response to toxin CES1;ADAMTS13 8180:[DB01183 DB00135] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;TAT;TH GO:0042755| eating behavior TH;OPRM1;OPRD1;OPRK1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC16A10;SLC16A2 GO:0001666| response to hypoxia TH;CREB1 GO:0014823| response to activity TH;CREB1 GO:0043252| sodium-independent organic anion transport SLC16A2;SLCO1A2;ALB GO:0032355| response to estradiol stimulus TH;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TAT GO:0071363| cellular response to growth factor stimulus CREB1;TH;OPRD1 GO:0006810| transport ABCB1;SLC16A2 GO:0007613| memory TH;CREB1 GO:0048545| response to steroid hormone stimulus TH;UGT1A1 GO:0007165| signal transduction OPRK1;YARS;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0042493| response to drug TH;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;TH GO:0035094| response to nicotine CREB1;TH GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;TH;OPRM1 GO:0045471| response to ethanol TH;OPRM1;UGT1A1;OPRK1 GO:0070848| response to growth factor stimulus TH;OPRM1 GO:0007626| locomotory behavior TH;OPRM1;OPRK1 8181:[DB01183 DB02340] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02340|N-Acetyl-Serine F13A1 common genes common pathways GO:0002576| platelet degranulation ALB;F13A1 8182:[DB01183 DB06477] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;DRD3;CREB1;UGT1A1 GO:0048149| behavioral response to ethanol DRD4;OPRM1;DRD2 GO:0042752| regulation of circadian rhythm DRD4;CREB1 GO:0008542| visual learning CREB1;DRD3;DRD2 GO:0043278| response to morphine DRD3;OPRK1;DRD2;OPRM1 GO:0035094| response to nicotine DRD2;CREB1 GO:0045471| response to ethanol OPRM1;OPRK1;DRD2;DRD3;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 GO:0007626| locomotory behavior OPRM1;DRD3;DRD2;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;DRD3;CREB1;DRD2;ESR1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;OPRM1 GO:0048148| behavioral response to cocaine DRD4;DRD3;DRD2;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;DRD2;OPRM1 GO:0008344| adult locomotory behavior OPRD1;DRD4 GO:0042220| response to cocaine OPRM1;DRD2;OPRK1;DRD3 GO:0000187| activation of MAPK activity DRD4;TLR4 GO:0007409| axonogenesis DRD2;CREB1 GO:0009636| response to toxin CES1;DRD2 GO:0048511| rhythmic process DRD4;CREB1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;DRD3;DRD4;OPRM1;OPRD1 GO:0007165| signal transduction ESR1;DRD4;OPRD1;OPRM1;DRD3;TLR4;CREB1;OPRK1;DRD2 GO:1900273| DRD2;CREB1 8183:[DB01183 DB02483] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;BST1 GO:0014070| response to organic cyclic compound LDHA;UGT1A1 GO:0001666| response to hypoxia CREB1;LDHA GO:0030890| positive regulation of B cell proliferation BST1;TLR4 GO:0043627| response to estrogen stimulus LDHA;OPRK1;ESR1 GO:0007584| response to nutrient UGT1A1;LDHA GO:0043065| positive regulation of apoptotic process LDHA;CREB1 GO:0050727| regulation of inflammatory response TLR4;BST1;ESR1 GO:0042493| response to drug ABCB1;CREB1;LDHA;UGT1A1 GO:0055114| oxidation-reduction process LDHA;CYP2C8;CYP3A4 8184:[DB01183 DB07092] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8185:[DB01183 DB00654] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;PTGFR;TLR4;UGT1A1 GO:0043066| negative regulation of apoptotic process PTGFR;ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO2B1;ALB GO:0007186| G-protein coupled receptor signaling pathway PTGFR;OPRD1;OPRM1;OPRK1 GO:0032355| response to estradiol stimulus PTGFR;ESR1 GO:0015711| organic anion transport SLC22A1;SLCO1A2 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;PTGFR;TLR4;CREB1;OPRK1 GO:0006811| ion transport SLC22A1;SLCO2B1;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLCO2B1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0010628| positive regulation of gene expression PTGFR;TLR4 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO2B1;ALB 8186:[DB01183 DB07907] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07907|(2S)-2-HYDROXYOCTANOIC ACID HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HAO1;CYP2C8 8187:[DB01183 DB04363] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways GO:0042167| heme catabolic process UGT1A1;BLVRB GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;BLVRB 8188:[DB01183 DB00263] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00263|Sulfisoxazole CYP2C9 common genes common pathways GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 8189:[DB01183 DB01099] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01099|Flucytosine DNMT1 common genes common pathways GO:0010628| positive regulation of gene expression DNMT1;TLR4 GO:0006355| regulation of transcription, DNA-dependent CREB1;DNMT1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DNMT1 GO:0006351| transcription, DNA-dependent ESR1;DNMT1;CREB1 8190:[DB01183 DB02857] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02857|Guanosine PNP common genes common pathways GO:0042493| response to drug PNP;CREB1;UGT1A1;ABCB1 GO:0006955| immune response OPRK1;PNP;TLR4;OPRD1 8191:[DB01183 DB06660] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06660|Saredutant TACR2 common genes common pathways GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;TACR2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;TACR2 GO:0007165| signal transduction OPRD1;OPRM1;TACR2;ESR1;OPRK1;TLR4;CREB1 GO:0033685| negative regulation of luteinizing hormone secretion TACR2;OPRK1 8192:[DB01183 DB07129] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07129|(2R)-1-(2,6-dimethylphenoxy)propan-2-amine PLAU common genes common pathways GO:0001666| response to hypoxia PLAU;CREB1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;PLAU;OPRK1;TLR4;CREB1 8193:[DB01183 DB12836] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes ABCB1;ALB common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;PTGER4;OPRK1 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0042908| xenobiotic transport ABCB1 GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport ABCB1 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PTGER4 GO:0072089| stem cell proliferation ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0045332| phospholipid translocation ABCB1 GO:0009267| cellular response to starvation ALB GO:0050729| positive regulation of inflammatory response TLR4;PTGER4 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0071260| cellular response to mechanical stimulus PTGER4;TLR4 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;PTGER4;UGT1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006955| immune response OPRK1;TLR4;PTGER4;OPRD1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CREB1;UGT1A1;ABCB1 8194:[DB01183 DB03064] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03064|3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;HAO1;CYP3A4 8195:[DB01183 DB00139] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process BBOX1;CYP2C8;P4HA1;P3H1;ALDH5A1;SDHC;SDHB;PLOD3;HSD17B6;ASPH;CYP3A4;TMLHE;P3H3;SDHA;SDHD;P4HA2;P3H2;PLOD1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;OXCT1 GO:0045893| positive regulation of transcription, DNA-dependent ASPH;ESR1;CREB1 GO:0045471| response to ethanol UGT1A1;OXCT1;OPRK1;OPRM1 GO:0042594| response to starvation OXCT1;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;HSD17B6 GO:0008152| metabolic process SUCLA2;SUCLG2;CES1;SUCLG1;UGT1A1;OXCT2;OXCT1;ALDH5A1 GO:0055085| transmembrane transport SLC13A3;SLCO1A2;SLC22A8;SLC13A1;SLC13A2;ABCB1 GO:0006811| ion transport SLC13A1;SLC22A8;SLC13A3;SLCO1A2;SLC25A10;SLC13A2 GO:0009636| response to toxin CES1;SLC22A8 GO:0007584| response to nutrient UGT1A1;OXCT1 GO:0008285| negative regulation of cell proliferation P3H1;P3H2;OPRM1;P3H3;ASPH GO:0014823| response to activity CREB1;OXCT1 GO:0001666| response to hypoxia PLOD1;CREB1 GO:0006810| transport SLC13A2;ABCB1 GO:0007186| G-protein coupled receptor signaling pathway SUCNR1;OPRK1;OPRM1;OPRD1 GO:0050821| protein stabilization CREB1;P3H1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0008202| steroid metabolic process CYP3A4;HSD17B6;UGT1A1;CYP2C8 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;SUCNR1;OPRK1;CREB1;TLR4 GO:0070588| calcium ion transmembrane transport ASPH;OPRM1 GO:0032870| cellular response to hormone stimulus PLOD3;UGT1A1 8196:[DB01183 DB02110] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006954| inflammatory response PTGS1;TLR4 GO:0055114| oxidation-reduction process CYP2C8;CYCS;CYP3A4;PTGS1 GO:0098869| PTGS1;ALB 8197:[DB01183 DB01854] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01854|5-Bromonicotinamide ART1 common genes common pathways 8198:[DB01183 DB06156] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0006810| transport SLC6A2;ABCB1 GO:0040018| positive regulation of multicellular organism growth CREB1;SLC6A3 GO:0007568| aging SLC6A3;CREB1 GO:0007613| memory SLC6A4;CREB1 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0009636| response to toxin CES1;SLC6A4 GO:0042220| response to cocaine OPRM1;SLC6A3;OPRK1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A2;SLC6A4;SLCO1A2 GO:0007626| locomotory behavior OPRK1;SLC6A3;OPRM1 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;SLC6A3 GO:0035094| response to nicotine SLC6A3;CREB1 GO:0007595| lactation CREB1;SLC6A3 GO:0042493| response to drug SLC6A4;SLC6A3;ABCB1;CREB1;SLC6A2;UGT1A1 GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;SLC6A2 8199:[DB01183 DB09016] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09016|Butriptyline SLC6A4;HRH1;HTR2A common genes common pathways GO:0007613| memory CREB1;HRH1;HTR2A;SLC6A4 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007568| aging HTR2A;CREB1 GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRM1;OPRD1;HRH1;OPRK1 GO:0007610| behavior OPRK1;HTR2A GO:0007165| signal transduction OPRM1;HRH1;OPRD1;ESR1;HTR2A;OPRK1;CREB1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;HTR2A GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC6A4 GO:0009636| response to toxin SLC6A4;CES1 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1;SLC6A4 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;HRH1;OPRD1;OPRM1;OPRK1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;HTR2A GO:0042493| response to drug CREB1;UGT1A1;ABCB1;HTR2A;SLC6A4 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 GO:0016032| viral reproduction HTR2A;CREB1 8200:[DB01183 DB01430] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0006811| ion transport ATP1A1;SLCO1A2 GO:0071260| cellular response to mechanical stimulus TLR4;ATP1A1 GO:0042493| response to drug ATP1A1;CREB1;UGT1A1;ABCB1 8201:[DB01183 DB04234] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04234|N2-({[(4-Bromophenyl)Methyl]Oxy}Carbonyl)-N1-[(1s)-1-Formylpentyl]-L-Leucinamide CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 8202:[DB01183 DB06701] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0007626| locomotory behavior OPRM1;SLC6A3;OPRK1 GO:0045471| response to ethanol OPRM1;SLC6A3;OPRK1;UGT1A1 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0007595| lactation CREB1;SLC6A3 GO:0035094| response to nicotine SLC6A3;CREB1 GO:0042493| response to drug SLC6A4;CREB1;SLC6A2;UGT1A1;SLC6A3;ABCB1 GO:0007268| synaptic transmission OPRD1;OPRM1;SLC6A2;OPRK1 GO:0007613| memory SLC6A4;CREB1 GO:0006810| transport SLC6A2;ABCB1 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging CREB1;SLC6A3 GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0010033| response to organic substance SLC6A4;CREB1;UGT1A1 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3;SLCO1A2;SLC6A4 GO:0042220| response to cocaine OPRK1;SLC6A3;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0009636| response to toxin CES1;SLC6A4 8203:[DB01183 DB13164] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13164|Olmutinib EGFR common genes common pathways GO:0001889| liver development UGT1A1;EGFR GO:0007623| circadian rhythm CREB1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1 GO:0042060| wound healing EGFR;OPRM1 GO:0071260| cellular response to mechanical stimulus TLR4;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;EGFR;ESR1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;EGFR GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1;ESR1 GO:0006468| protein phosphorylation CREB1;EGFR GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;EGFR GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0007165| signal transduction EGFR;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TLR4;OPRM1;ESR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;EGFR;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 8204:[DB01183 DB09334] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09334|Seractide acetate MC2R common genes common pathways GO:0007218| neuropeptide signaling pathway OPRK1;MC2R;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;MC2R GO:0007165| signal transduction MC2R;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger MC2R;OPRM1;OPRD1 8205:[DB01183 DB03752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4 GO:0006954| inflammatory response TLR4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP2C8 GO:0098869| ALB;PTGS1 8206:[DB01183 DB04017] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04017|Clorgiline MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8 8207:[DB01183 DB08291] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08291|N-(3-AMINOPROPYL)-2-NITROBENZENAMINE KAT2B common genes common pathways GO:0016579| protein deubiquitination KAT2B;ESR1 GO:0008285| negative regulation of cell proliferation KAT2B;OPRM1 GO:0048511| rhythmic process CREB1;KAT2B GO:0006338| chromatin remodeling ESR1;KAT2B GO:0045893| positive regulation of transcription, DNA-dependent ESR1;KAT2B;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;KAT2B GO:0016032| viral reproduction CREB1;KAT2B GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;KAT2B GO:0006351| transcription, DNA-dependent KAT2B;ESR1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;KAT2B;CREB1;TLR4 8208:[DB01183 DB04614] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways 8209:[DB01183 DB06848] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways 8210:[DB01183 DB08695] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;HPGDS;CREB1;TLR4;OPRK1 GO:0007626| locomotory behavior OPRM1;HPGDS;OPRK1 GO:0006629| lipid metabolic process HPGDS;CYP3A4 8211:[DB01183 DB14050] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0006954| inflammatory response TRPV1;TLR4 GO:0007600| sensory perception OPRK1;TRPV2;OPRM1 GO:0042493| response to drug TRPA1;CREB1;UGT1A1;ABCB1 GO:0043065| positive regulation of apoptotic process TRPV1;CREB1 GO:0006629| lipid metabolic process CYP3A4;DAGLA;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV1 GO:1990090| CREB1;TRPV1 GO:0019233| sensory perception of pain OPRD1;OPRM1;TRPA1;OPRK1;TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;TRPV1 GO:0010033| response to organic substance UGT1A1;TRPA1;CREB1 GO:0014070| response to organic cyclic compound TRPA1;UGT1A1 GO:0006811| ion transport SLCO1A2;TRPV2;TRPA1;TRPV1 GO:0055085| transmembrane transport SLCO1A2;TRPV2;TRPA1;ABCB1;TRPV1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TRPV1;TLR4 GO:0070588| calcium ion transmembrane transport TRPV2;OPRM1;TRPV1;TRPA1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;TRPV1 GO:0006810| transport TRPV2;ABCB1;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;ESR1;OPRM1 8212:[DB01183 DB01245] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0030890| positive regulation of B cell proliferation CHRNB2;TLR4 GO:0001666| response to hypoxia CREB1;CHRNB2;CHRNA4 GO:0042220| response to cocaine OPRM1;CHRNB2;OPRK1 GO:0006811| ion transport SLCO1A2;CHRNA4;CHRNA2;CHRNB2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;CHRNB2;CHRNA4;CHRNA2;ESR1;OPRM1;OPRD1 GO:0007613| memory CHRNB2;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0035094| response to nicotine CHRNB2;CREB1;CHRNA2;CHRNA4 GO:0008542| visual learning CHRNB2;CREB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;BCHE GO:0007268| synaptic transmission OPRK1;CHRNA4;OPRD1;OPRM1 GO:0033603| positive regulation of dopamine secretion OPRK1;CHRNB2 GO:0007626| locomotory behavior CHRNB2;OPRK1;OPRM1;CHRNA4 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNB2;OPRM1;CHRNA4;CHRNA2 GO:0045471| response to ethanol OPRK1;CHRNB2;UGT1A1;OPRM1 GO:0019233| sensory perception of pain CHRNB2;OPRK1;OPRM1;OPRD1;CHRNA4 8213:[DB01183 DB05785] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0010033| response to organic substance UGT1A1;CREB1;JUN GO:0008285| negative regulation of cell proliferation JUN;OPRM1;RARG;RARA;RARB GO:0010628| positive regulation of gene expression RARA;RARG;TLR4 GO:0048146| positive regulation of fibroblast proliferation ESR1;JUN GO:0008584| male gonad development RARA;ESR1 GO:1990830| RARG;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway JUN;CREB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;JUN;ESR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade JUN;OPRM1;TLR4 GO:0014070| response to organic cyclic compound JUN;UGT1A1 GO:0007165| signal transduction RARB;OPRK1;CREB1;TLR4;RARA;OPRM1;OPRD1;ESR1 GO:0032870| cellular response to hormone stimulus JUN;UGT1A1 GO:0032689| negative regulation of interferon-gamma production RARA;TLR4 GO:0032720| negative regulation of tumor necrosis factor production TLR4;RARA GO:0007568| aging JUN;CREB1 GO:0006468| protein phosphorylation CREB1;RARA GO:0032355| response to estradiol stimulus RARA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARB;RARA;RARG;ESR1 GO:0071391| cellular response to estrogen stimulus ESR1;RARA GO:0008361| regulation of cell size CREB1;RARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;JUN;RARA;CREB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1;RARA GO:0042493| response to drug CREB1;UGT1A1;ABCB1;JUN GO:0006355| regulation of transcription, DNA-dependent RARB;CREB1;RARG;RARA;ESR1;JUN GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;RARA;ESR1;RARB GO:0042981| regulation of apoptotic process CREB1;RARA;ESR1 GO:0043066| negative regulation of apoptotic process JUN;RARA;RARG;RARB;ALB GO:0043065| positive regulation of apoptotic process RARG;JUN;RARB;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;RARA GO:0009314| response to radiation OPRK1;JUN;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARB;TLR4;CREB1;RARG;RARA;ESR1;JUN GO:0043401| steroid hormone mediated signaling pathway RARB;ESR1;RARG;RARA GO:0001889| liver development RARA;JUN;UGT1A1 GO:0006351| transcription, DNA-dependent CREB1;RARB;JUN;ESR1;RARA;RARG GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;RARA GO:0007623| circadian rhythm JUN;CREB1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;JUN 8214:[DB01183 DB02580] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02580|Pentaglyme PFN2;gpmA;purA common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PFN2 GO:0050821| protein stabilization CREB1;PFN2 8215:[DB01183 DB00119] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0001889| liver development PKM;UGT1A1 GO:0045471| response to ethanol UGT1A1;OPRK1;ABAT;OPRM1 GO:0008152| metabolic process UGT1A1;PKLR;CES1;PKM;PDHB;PC GO:0048148| behavioral response to cocaine OPRK1;ABAT GO:0007626| locomotory behavior OPRM1;ABAT;OPRK1 GO:0006629| lipid metabolic process SLC16A1;PC;CYP3A4 GO:0032094| response to food SLC16A1;OPRM1 GO:0042493| response to drug CREB1;UGT1A1;ABAT;ABCB1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1;PC GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PDHB GO:0035094| response to nicotine CREB1;ABAT GO:0043252| sodium-independent organic anion transport ALB;SLCO2A1;SLC16A2;SLCO1A2 GO:0007568| aging CREB1;ABAT GO:0006810| transport ABCB1;SLC16A2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;AGXT2 GO:0031100| organ regeneration PKM;UGT1A1 GO:0042220| response to cocaine OPRK1;ABAT;OPRM1 GO:0032868| response to insulin stimulus PKM;OPRK1 GO:0055085| transmembrane transport SLC16A2;SLC16A1;SLC16A7;SLCO1A2;SLC16A10;SLC16A4;ABCB1;SLC16A5;SLC16A6;SLC16A8;SLCO2A1;SLC16A3 GO:0001666| response to hypoxia PKM;ABAT;PKLR;CREB1 GO:0010033| response to organic substance CREB1;UGT1A1;PKM GO:0007584| response to nutrient UGT1A1;PKLR;PKM 8216:[DB01183 DB02623] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways GO:0010628| positive regulation of gene expression CDC42;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation CDC42;OPRD1 GO:0030154| cell differentiation CREB1;CDC42 GO:0006468| protein phosphorylation CREB1;CDC42 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CDC42;CREB1 GO:0046330| positive regulation of JNK cascade CDC42;TLR4 8217:[DB01183 DB01805] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways GO:0007586| digestion UGT1A1;PRSS2;PRSS1 8218:[DB01183 DB02185] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02185|2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One LCTL common genes common pathways 8219:[DB01183 DB11201] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007613| memory CREB1;PTGS2 GO:0007568| aging PTGS2;CREB1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TLR4 GO:0098869| PTGS2;PTGS1;ALB GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;PTGS2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;PTGS2;OPRM1 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0050727| regulation of inflammatory response TLR4;ESR1;PTGS2 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;PTGS1 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;PTGS2 GO:0006954| inflammatory response TLR4;PTGS2;PTGS1 8220:[DB01183 DB02418] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways GO:0002756| MyD88-independent toll-like receptor signaling pathway UBE2D2;TLR4 GO:0035666| TRIF-dependent toll-like receptor signaling pathway TLR4;UBE2D2 8221:[DB01183 DB11626] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11626|Tasonermin TNFRSF1A;TNFRSF1B common genes common pathways GO:0007568| aging TNFRSF1B;CREB1 GO:0050729| positive regulation of inflammatory response TLR4;TNFRSF1A GO:0071363| cellular response to growth factor stimulus OPRD1;TNFRSF1B;CREB1 GO:0007165| signal transduction CREB1;TLR4;TNFRSF1A;OPRK1;OPRM1;OPRD1;ESR1 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNFRSF1A GO:0042742| defense response to bacterium TLR4;TNFRSF1A GO:0016032| viral reproduction TNFRSF1A;CREB1 GO:0006955| immune response OPRD1;TNFRSF1A;TNFRSF1B;OPRK1;TLR4 GO:0006954| inflammatory response TNFRSF1B;TNFRSF1A;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNFRSF1A GO:0097190| apoptotic signaling pathway TNFRSF1B;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;TNFRSF1A;TNFRSF1B;UGT1A1;TLR4 GO:0071260| cellular response to mechanical stimulus TNFRSF1A;TLR4 GO:0042981| regulation of apoptotic process ESR1;TNFRSF1A;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;TNFRSF1B;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFRSF1A;TLR4;CREB1;ESR1 8222:[DB01183 DB00392] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0006811| ion transport GRIN3A;SLCO1A2 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient BCHE;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CHRM1;CHRM2;OPRM1;OPRD1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0070588| calcium ion transmembrane transport GRIN3A;OPRM1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;CHRM1;CHRM2 GO:0042493| response to drug ABCB1;UGT1A1;BCHE;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN3A;OPRM1 GO:0045471| response to ethanol OPRM1;OPRK1;GRIN3A;UGT1A1 8223:[DB01183 DB08632] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways GO:0098869| ALB;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;HBB;ESR1;OPRM1 GO:0006898| receptor-mediated endocytosis ALB;HBA1;HBB 8224:[DB01183 DB09559] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09559|Necitumumab EGFR common genes common pathways GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;EGFR GO:0006468| protein phosphorylation EGFR;CREB1 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;EGFR;TLR4 GO:0007165| signal transduction TLR4;CREB1;EGFR;OPRK1;OPRD1;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;EGFR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CREB1;ESR1 GO:0007623| circadian rhythm CREB1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;EGFR GO:0042060| wound healing EGFR;OPRM1 GO:0001889| liver development UGT1A1;EGFR GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;EGFR;ESR1 GO:0071260| cellular response to mechanical stimulus TLR4;EGFR 8225:[DB01183 DB00483] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;OPRM1 GO:0035094| response to nicotine CHRNA2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CHRM2;CHRM1;OPRD1;OPRM1;CHRM5 GO:0007165| signal transduction ESR1;CHRM1;CHRM2;OPRM1;CHRM5;OPRD1;CHRNA2;CREB1;TLR4;OPRK1 GO:0006811| ion transport CHRNA2;SLCO1A2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CHRM2 8226:[DB01183 DB07297] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways GO:0045087| innate immune response TLR4;LCK GO:0042493| response to drug LCK;ABCB1;UGT1A1;CREB1 GO:0016032| viral reproduction CREB1;LCK GO:0006468| protein phosphorylation CREB1;LCK 8227:[DB01183 DB03680] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03680|Tartronate ME2;ME3 common genes common pathways GO:0008152| metabolic process ME2;CES1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;ME2;ME3;CYP3A4 8228:[DB01183 DB00416] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways GO:0035094| response to nicotine CHRNA2;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA2 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0007165| signal transduction CHRNA2;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 8229:[DB01183 DB01914] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0008152| metabolic process CES1;GCK;UGT1A1;HK1 GO:0071260| cellular response to mechanical stimulus TLR4;SLC2A1 GO:0045471| response to ethanol OPRM1;OPRK1;SLC2A4;UGT1A1 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;HK1 GO:0042908| xenobiotic transport ABCB1;SLC2A1 GO:0006810| transport SLC5A2;ABCB1 GO:0071456| cellular response to hypoxia SLC2A4;OPRD1 GO:0001666| response to hypoxia SLC2A8;CREB1 GO:0006811| ion transport SLC5A1;SLCO1A2;SLC5A2 GO:0032868| response to insulin stimulus OPRK1;SLC2A1 GO:0055085| transmembrane transport SLC2A9;SLC2A12;SLC2A3;SLC2A1;SLC2A8;SLCO1A2;SLC2A7;SLC5A1;SLC2A11;SLC2A6;SLC2A4;SLC2A5;SLC2A10;ABCB1;SLC5A2;SLC2A2 8230:[DB01183 DB04005] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways GO:0008152| metabolic process UCK2;UGT1A1;CES1 8231:[DB01183 DB03376] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03376|'5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine EPRS common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;EPRS 8232:[DB01183 DB06506] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0007610| behavior HTR1A;OPRK1 GO:0007165| signal transduction OPRD1;OPRM1;HTR1A;ESR1;OPRK1;TLR4;CREB1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;OPRM1;OPRD1;OPRK1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 8233:[DB01183 DB00063] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00063|Eptifibatide ITGB3 common genes common pathways GO:0042060| wound healing OPRM1;ITGB3 GO:0002576| platelet degranulation ITGB3;ALB GO:0016032| viral reproduction CREB1;ITGB3 8234:[DB01183 DB04917] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04917|Renzapride HTR3A;HTR4 common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;HTR4;OPRM1;OPRK1;HTR3A;TLR4;CREB1 GO:0071363| cellular response to growth factor stimulus OPRD1;HTR3A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;HTR4;OPRM1;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR4;OPRM1;OPRD1 GO:0006811| ion transport SLCO1A2;HTR3A GO:0042220| response to cocaine OPRM1;OPRK1;HTR3A GO:0045471| response to ethanol OPRK1;HTR3A;UGT1A1;OPRM1 GO:0007268| synaptic transmission OPRK1;HTR3A;OPRD1;OPRM1;HTR4 8235:[DB01183 DB00149] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways GO:1990830| BCAT2;CREB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;LCMT1 GO:0055085| transmembrane transport SLC16A2;SLC16A10;SLCO1A2;ABCB1 GO:0006810| transport SLC16A2;ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC16A2 GO:0008361| regulation of cell size CREB1;LARS GO:0042981| regulation of apoptotic process ESR1;LCMT1;CREB1 GO:0008152| metabolic process BCAT1;CES1;BCAT2;UGT1A1 8236:[DB01183 DB08251] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways GO:0032355| response to estradiol stimulus CASP3;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0010033| response to organic substance CASP3;UGT1A1;CREB1 GO:0001666| response to hypoxia CREB1;CASP3 GO:0014070| response to organic cyclic compound UGT1A1;CASP3 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;CREB1 GO:0097190| apoptotic signaling pathway CASP3;TLR4 GO:0032496| response to lipopolysaccharide CASP3;OPRM1;TLR4;UGT1A1 GO:0042060| wound healing OPRM1;CASP3 GO:0035094| response to nicotine CASP3;CREB1 GO:0042493| response to drug CASP3;ABCB1;UGT1A1;CREB1 8237:[DB01183 DB03575] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03575|Phencyclidine GRIN3A;SIGMAR1;CYP2B6 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIN3A GO:0045471| response to ethanol OPRM1;UGT1A1;GRIN3A;OPRK1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2B6;CES1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2B6;CYP3A4 GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;SIGMAR1;OPRD1 GO:0008202| steroid metabolic process CYP2B6;UGT1A1;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2B6;CYP2C8;CYP3A4 GO:0070588| calcium ion transmembrane transport OPRM1;GRIN3A GO:0006811| ion transport SLCO1A2;GRIN3A 8238:[DB01183 DB01917] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC22A4 GO:0006811| ion transport SLC22A4;SLCO1A2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:1904646| ADRB2;TLR4 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;OPRK1;OPRM1;OPRD1;ADRB2 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007165| signal transduction OPRD1;OPRM1;ADRB2;ESR1;ADRB1;OPRK1;TLR4;CREB1 GO:0015711| organic anion transport SLC22A4;SLCO1A2 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 8239:[DB01183 DB03256] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways GO:0008152| metabolic process UGT1A1;FTCD;CES1 8240:[DB01183 DB08486] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08486|Efaproxiral HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;HBB;TLR4 GO:0098869| HBB;HBA1;ALB GO:0006898| receptor-mediated endocytosis HBB;HBA1;ALB 8241:[DB01183 DB08302] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;PPARG;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0048511| rhythmic process PPARG;CREB1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;PPARG GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PPARG 8242:[DB01183 DB07842] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;ESR1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation UGT1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0042493| response to drug UGT1A1;PPARG;CREB1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;PPARG;CREB1;OPRK1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0048511| rhythmic process CREB1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 8243:[DB01183 DB09273] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;UGT1A1;ADORA2A;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;CREB1;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0006954| inflammatory response ADORA2A;TLR4 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0007600| sensory perception OPRM1;ADORA2A;OPRK1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;TLR4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;ADORA2A GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:0007626| locomotory behavior ADORA2A;OPRK1;OPRM1 GO:0008152| metabolic process CES1;PDE2A;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus PDE2A;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PDE2A GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0071260| cellular response to mechanical stimulus TLR4;PDE2A GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042755| eating behavior OPRK1;ADORA2A;OPRD1;OPRM1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;ADORA2A GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation ADORA2A;OPRM1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway ADORA2A;PDE2A;OPRK1;ADRB2;OPRM1;OPRD1 GO:0050729| positive regulation of inflammatory response PDE2A;TLR4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0070588| calcium ion transmembrane transport OPRM1;PDE2A GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0007165| signal transduction OPRD1;OPRM1;ADRB2;ESR1;OPRK1;PDE2A;ADORA2A;TLR4;CREB1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 8244:[DB01183 DB05308] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05308|ANX-510 TYMS common genes common pathways GO:0009636| response to toxin CES1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0007568| aging TYMS;CREB1 GO:0042493| response to drug UGT1A1;TYMS;CREB1;ABCB1 GO:0007623| circadian rhythm CREB1;TYMS GO:0045471| response to ethanol UGT1A1;TYMS;OPRK1;OPRM1 8245:[DB01183 DB04764] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04764|[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE TPSB2 common genes common pathways 8246:[DB01183 DB00732] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00732|Atracurium besylate CHRNA2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA2 GO:0035094| response to nicotine CREB1;CHRNA2 GO:0007165| signal transduction CHRNA2;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0006811| ion transport CHRNA2;SLCO1A2 8247:[DB01183 DB07302] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process PPARG;CREB1 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;PPARG;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRD1;OPRM1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0042493| response to drug UGT1A1;PPARG;CREB1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045087| innate immune response TLR4;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG 8248:[DB01183 DB02166] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02166|Propidium ACHE common genes common pathways 8249:[DB01183 DB14597] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14597|Lanadelumab KLKB1 common genes common pathways GO:0006954| inflammatory response TLR4;KLKB1 8250:[DB01183 DB07047] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process TTR;ALB 8251:[DB01183 DB09517] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;HBB;ESR1;OPRM1 GO:0098869| HBA1;HBB;ALB 8252:[DB01183 DB07144] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 8253:[DB01183 DB04396] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04396|Thiodigalactoside NCAN;LGALS1 common genes common pathways GO:0044267| cellular protein metabolic process LGALS1;ALB GO:0007165| signal transduction OPRM1;OPRD1;ESR1;LGALS1;CREB1;TLR4;OPRK1 GO:0043687| post-translational protein modification ALB;LGALS1 GO:0042493| response to drug LGALS1;UGT1A1;CREB1;ABCB1 GO:0042981| regulation of apoptotic process CREB1;ESR1;LGALS1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LGALS1;TLR4 8254:[DB01183 DB07670] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP2C18 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C18 GO:0055114| oxidation-reduction process CYP2C8;CYP2C18;CYP3A4 8255:[DB01183 DB06247] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06247|CX516 GRIA1 common genes common pathways GO:0007268| synaptic transmission OPRM1;OPRD1;GRIA1;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIA1 GO:0006811| ion transport GRIA1;SLCO1A2 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;GRIA1;OPRK1 8256:[DB01183 DB07740] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;HMGCS1;CYP2C8;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;HMGCS1 GO:0010033| response to organic substance UGT1A1;HMGCS1;CREB1 GO:0008584| male gonad development ESR1;HMGCS1 GO:0001889| liver development HMGCS1;UGT1A1 GO:0006695| cholesterol biosynthetic process HMGCS1;CES1 GO:0006629| lipid metabolic process CYP3A4;HMGCS1 GO:0008152| metabolic process CES1;UGT1A1;HMGCS1 GO:0042493| response to drug CREB1;HMGCS1;UGT1A1;ABCB1 8257:[DB01183 DB02404] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways 8258:[DB01183 DB04469] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4 GO:0071222| cellular response to lipopolysaccharide PDE4D;OPRK1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;PDE4D;OPRM1 GO:0007568| aging PDE4D;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;PDE4D;ESR1;OPRK1;CREB1;TLR4 8259:[DB01183 DB00595] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00595|Oxytetracycline rpsI;rpsD;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0055085| transmembrane transport SLC22A7;SLC22A11;SLC22A8;SLCO1A2;ABCB1;SLC22A6 GO:0009636| response to toxin SLC22A8;CES1 GO:0006811| ion transport SLC22A8;SLCO1A2;SLC22A7;SLC22A11 GO:0015711| organic anion transport SLC22A6;SLC22A11;SLC22A7;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLCO1A2;SLC22A7;SLC22A11 8260:[DB01183 DB06530] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06530|Resiquimod TLR7;TLR8 common genes common pathways GO:0045087| innate immune response TLR8;TLR7;TLR4 GO:0071260| cellular response to mechanical stimulus TLR8;TLR7;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR7;TLR4 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR8;TLR4;TLR7 GO:0050718| positive regulation of interleukin-1 beta secretion TLR8;TLR4 GO:0006954| inflammatory response TLR4;TLR7;TLR8 GO:0006955| immune response OPRD1;TLR7;TLR4;OPRK1 GO:0050707| regulation of cytokine secretion TLR4;TLR8 GO:0007252| I-kappaB phosphorylation TLR4;TLR7 GO:0051607| defense response to virus OPRK1;TLR8;TLR7 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR8;TLR7;TLR4 GO:0007165| signal transduction CREB1;TLR7;TLR4;OPRK1;TLR8;OPRM1;OPRD1;ESR1 GO:0032722| positive regulation of chemokine production TLR7;TLR4 GO:0002376| immune system process TLR8;TLR4;TLR7 GO:0032757| positive regulation of interleukin-8 production TLR4;TLR7 GO:0045359| positive regulation of interferon-beta biosynthetic process TLR4;TLR7;TLR8 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TLR8 GO:0032755| positive regulation of interleukin-6 production TLR7;TLR4 GO:0002224| toll-like receptor signaling pathway TLR8;TLR7;TLR4 GO:0050729| positive regulation of inflammatory response TLR4;TLR7 8261:[DB01183 DB06607] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways GO:0048863| stem cell differentiation ESR1;EPCAM GO:0006955| immune response FCGR3A;OPRD1;FCGR1A;OPRK1;TLR4;FCGR3B GO:0010629| negative regulation of gene expression CD3E;CREB1;OPRD1;ESR1 GO:0045087| innate immune response TLR4;FCGR1A GO:0042981| regulation of apoptotic process ESR1;CREB1;CD3E GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;EPCAM;CREB1;TLR4 GO:0097190| apoptotic signaling pathway TLR4;CD3E GO:0032729| positive regulation of interferon-gamma production TLR4;CD3E GO:0007584| response to nutrient CD3E;UGT1A1 GO:0010628| positive regulation of gene expression CD3E;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;FCGR1A;OPRK1;TLR4;CREB1 GO:0002376| immune system process TLR4;CD3E;FCGR2A;FCGR1A GO:0006898| receptor-mediated endocytosis ALB;FCGR1A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CD3E;OPRD1;OPRM1 8262:[DB01183 DB04801] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04801|cis-Vaccenic acid PPARD common genes common pathways GO:0042060| wound healing OPRM1;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARD GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARD GO:0006351| transcription, DNA-dependent ESR1;PPARD;CREB1 GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0071222| cellular response to lipopolysaccharide PPARD;OPRK1;TLR4 GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARD;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;ESR1 GO:0030154| cell differentiation CREB1;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0045600| positive regulation of fat cell differentiation CREB1;PPARD GO:0010033| response to organic substance PPARD;UGT1A1;CREB1 GO:0014823| response to activity PPARD;CREB1 8263:[DB01183 DB05391] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05391|liposomal prostaglandin E1 GP1BA common genes common pathways 8264:[DB01183 DB00266] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes ALB common pathways GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;VKORC1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C9;UGT1A1;CYP2C8;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;NQO1 GO:0051659| maintenance of mitochondrion location ALB GO:0007568| aging CREB1;NQO1 GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0007584| response to nutrient UGT1A1;NQO1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound UGT1A1;NQO1 GO:0009636| response to toxin CES1;NQO1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C9;NQO1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0002576| platelet degranulation ALB GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol OPRM1;UGT1A1;NQO1;OPRK1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0043086| negative regulation of catalytic activity UGT1A1;NQO1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process VKORC1;CYP3A4;CRYZ;CYP2C9;NQO1;CYP2C8 GO:0043687| post-translational protein modification ALB 8265:[DB01183 DB09421] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09421|Protirelin TRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway TRHR;OPRK1;OPRD1;OPRM1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;TRHR;OPRD1;OPRM1;ESR1 8266:[DB01183 DB07652] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07652|1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE POLK;rnhA common genes common pathways 8267:[DB01183 DB00046] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways GO:0006955| immune response OPRK1;TLR4;OPRD1;IGF1R GO:0045893| positive regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0043066| negative regulation of apoptotic process ALB;IGF1R GO:1904646| IGF1R;TLR4 GO:0008584| male gonad development ESR1;INSR GO:0000187| activation of MAPK activity TLR4;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;INSR GO:0007165| signal transduction ESR1;OPRD1;IGF1R;OPRM1;TLR4;CREB1;OPRK1 GO:0071363| cellular response to growth factor stimulus CREB1;INSR;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;INSR GO:0006468| protein phosphorylation CREB1;INSR;IGF1R GO:0007613| memory INSR;CREB1 8268:[DB01183 DB07282] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport ABCB1;TTR 8269:[DB01183 DB02427] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 8270:[DB01183 DB06694] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ADRA2C;ESR1;ADRA2B;ADRA1B;ADRA1D;CREB1;TLR4;ADRA1A;ADRA2A;OPRK1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A GO:0007568| aging CREB1;ADRA1A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ESR1;OPRM1;ADRA1B GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;OPRK1;ADRA1A;ADRA1D;ADRA1B;ADRA2C;ADRA2B;OPRM1;OPRD1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ADRA1A;ADRA1D;ADRA1B;ESR1;OPRD1;OPRM1 GO:0042493| response to drug ADRA1A;ABCB1;UGT1A1;CREB1 8271:[DB01183 DB05289] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05289|Tarenflurbil IKBKG common genes common pathways GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKG;TLR4 GO:0006351| transcription, DNA-dependent IKBKG;CREB1;ESR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;IKBKG;ESR1 GO:0045087| innate immune response TLR4;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;IKBKG GO:1901215| CREB1;IKBKG GO:0016032| viral reproduction IKBKG;CREB1 GO:0006955| immune response OPRD1;TLR4;OPRK1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IKBKG GO:0006954| inflammatory response IKBKG;TLR4 GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKG;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;TLR4 GO:0000187| activation of MAPK activity IKBKG;TLR4 GO:0016579| protein deubiquitination IKBKG;ESR1 8272:[DB01183 DB00168] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1;TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;OPRM1 GO:0006629| lipid metabolic process TRPV1;CYP3A4 GO:1990090| TRPV1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;ESR1 GO:0043065| positive regulation of apoptotic process TRPV1;CREB1 GO:0006954| inflammatory response TLR4;TRPV1 GO:0006810| transport ABCB1;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;ESR1;OPRM1 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;SLC22A11;SLC22A6;ALB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;TAS1R2;OPRM1;TAS1R3;OPRD1 GO:0071363| cellular response to growth factor stimulus CREB1;TRPV1;OPRD1 GO:0007165| signal transduction ESR1;TAS1R3;OPRM1;OPRD1;OPRK1;CREB1;TLR4;TAS1R2 GO:0015711| organic anion transport SLC22A6;SLC22A11;SLCO1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TLR4;OPRM1;ESR1 GO:0070588| calcium ion transmembrane transport TRPV1;OPRM1 GO:0055085| transmembrane transport SLC22A11;SLCO1A2;SLC22A8;TRPV1;ABCB1;SLC22A6 GO:0009636| response to toxin CES1;SLC22A8 GO:0006811| ion transport TRPV1;SLC22A11;SLCO1A2;SLC22A8 8273:[DB01183 DB07873] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process GGPS1;CES1 8274:[DB01183 DB12307] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0036378| CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;TLR4 GO:0000187| activation of MAPK activity TLR4;HGF GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2C8;CYP3A5;UGT1A1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0006468| protein phosphorylation CREB1;KDR GO:0030154| cell differentiation CREB1;KDR GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0031100| organ regeneration HGF;UGT1A1 GO:0032715| negative regulation of interleukin-6 production TLR4;HGF GO:0035729| cellular response to hepatocyte growth factor stimulus HGF;CREB1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0010629| negative regulation of gene expression ESR1;OPRD1;KDR;CREB1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP3A43;CYP3A7;CYP3A4 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0016032| viral reproduction CREB1;KDR GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0001889| liver development HGF;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;HGF GO:0002576| platelet degranulation HGF;ALB GO:0043066| negative regulation of apoptotic process ALB;HGF;KDR GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP3A7;CYP3A4;CES1 GO:0032733| positive regulation of interleukin-10 production TLR4;HGF GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 8275:[DB01183 DB12436] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12436|Vofopitant TACR1 common genes common pathways GO:0045471| response to ethanol OPRM1;TACR1;UGT1A1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger TACR1;OPRM1;OPRD1;ESR1;OPRK1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;TACR1 GO:0050671| positive regulation of lymphocyte proliferation TLR4;TACR1 GO:0007268| synaptic transmission OPRK1;TACR1;OPRM1;OPRD1 GO:0046887| positive regulation of hormone secretion CREB1;TACR1 GO:0035094| response to nicotine TACR1;CREB1 GO:0043278| response to morphine TACR1;OPRM1;OPRK1 GO:0006954| inflammatory response TLR4;TACR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;TACR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;TACR1;OPRM1;OPRK1 GO:0032355| response to estradiol stimulus TACR1;ESR1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TACR1;OPRK1;TLR4;CREB1 GO:0042755| eating behavior TACR1;OPRM1;OPRD1;OPRK1 GO:0014070| response to organic cyclic compound TACR1;UGT1A1 8276:[DB01183 DB06920] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06920|Eribaxaban F10 common genes common pathways 8277:[DB01183 DB06953] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06953|2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FNTA 8278:[DB01183 DB04105] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04105|N-Heptylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;CYP2C8;CYP3A4 8279:[DB01183 DB05407] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05407|TBC-3711 EDN1 common genes common pathways GO:0042493| response to drug EDN1;ABCB1;CREB1;UGT1A1 GO:0046887| positive regulation of hormone secretion CREB1;EDN1 GO:0035094| response to nicotine EDN1;CREB1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;EDN1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;EDN1 GO:0019233| sensory perception of pain OPRM1;OPRD1;EDN1;OPRK1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;EDN1;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDN1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;EDN1 GO:0071560| cellular response to transforming growth factor beta stimulus EDN1;CREB1 GO:0071398| cellular response to fatty acid EDN1;CREB1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;EDN1;OPRK1 GO:0014823| response to activity CREB1;EDN1 GO:0001666| response to hypoxia EDN1;CREB1 GO:0071456| cellular response to hypoxia OPRD1;EDN1 GO:0007204| elevation of cytosolic calcium ion concentration EDN1;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDN1;OPRK1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;EDN1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;EDN1 8280:[DB01183 DB12555] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12555|Nelotanserin HTR2A common genes common pathways GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2A;ESR1;OPRD1;OPRM1 GO:0019233| sensory perception of pain HTR2A;OPRD1;OPRM1;OPRK1 GO:0016032| viral reproduction CREB1;HTR2A GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1;HTR2A GO:0042493| response to drug HTR2A;CREB1;UGT1A1;ABCB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;HTR2A;CREB1;TLR4;OPRK1 GO:0007610| behavior HTR2A;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1 GO:0007613| memory HTR2A;CREB1 GO:0007568| aging HTR2A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRD1;OPRM1;OPRK1 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;TLR4 8281:[DB01183 DB06469] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06469|Lestaurtinib FLT3;CYP3A4 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0031100| organ regeneration UGT1A1;FLT3 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0030154| cell differentiation FLT3;CREB1 GO:0006468| protein phosphorylation FLT3;CREB1 GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0042981| regulation of apoptotic process CREB1;ESR1;FLT3 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 8282:[DB01183 DB06741] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06741|Gavestinel GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;UGT1A1;UGT1A3;UGT1A9;UGT2B4 common genes UGT1A1 common pathways GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007613| memory CREB1;GRIN2A;GRIN1 GO:0006810| transport GRIN2B;GRIN2A;GRIN2C;ABCB1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A9;UGT1A1;CYP2C8;CYP3A4;UGT1A3 GO:0031100| organ regeneration UGT1A1 GO:0070588| calcium ion transmembrane transport GRIN3B;GRIN3A;OPRM1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:1900273| CREB1;GRIN2A GO:0008344| adult locomotory behavior GRIN2D;GRIN1;OPRD1 GO:0006811| ion transport GRIN3B;GRIN3A;GRIN2C;GRIN2A;GRIN2B;GRIN2D;GRIN1;SLCO1A2 GO:0051930| regulation of sensory perception of pain GRIN2A;GRIN2D;OPRM1;OPRD1;OPRK1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9;UGT1A3 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A1;UGT1A9 GO:0014070| response to organic cyclic compound UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9;UGT1A3 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A9;UGT1A1 GO:1903428| TLR4;GRIN1 GO:1904646| GRIN2A;GRIN1;TLR4 GO:0045471| response to ethanol OPRK1;GRIN3A;UGT1A1;GRIN2A;GRIN2B;OPRM1;GRIN1 GO:0070980| biphenyl catabolic process UGT1A1 GO:1904224| UGT1A3;UGT1A1;UGT1A9 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN3A;GRIN2C;GRIN3B;GRIN2B;GRIN1;GRIN2D;OPRM1;GRIN2A GO:0019233| sensory perception of pain OPRK1;GRIN2A;OPRM1;GRIN1;OPRD1 GO:0001889| liver development UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0007586| digestion UGT1A1 GO:0043065| positive regulation of apoptotic process GRIN1;GRIN2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;GRIN1 GO:0008152| metabolic process UGT2B4;UGT1A1;UGT1A9;CES1;UGT1A3 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;UGT2B4;UGT1A9;CYP2C8 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A3;UGT1A9;UGT1A1;UGT2B4 GO:0042493| response to drug GRIN2A;ABCB1;UGT1A1;CREB1 GO:0007268| synaptic transmission OPRD1;OPRM1;GRIN2B;GRIN2A;OPRK1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9;UGT1A3 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:0043278| response to morphine GRIN1;OPRM1;OPRK1 GO:0008542| visual learning GRIN1;GRIN2A;CREB1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 8283:[DB01183 DB08655] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways GO:0007165| signal transduction CREBBP;TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0001666| response to hypoxia CREB1;CREBBP GO:0048511| rhythmic process CREB1;CREBBP GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;CREBBP;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1;CREBBP GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CREBBP GO:0006351| transcription, DNA-dependent CREB1;CREBBP;ESR1 GO:0016032| viral reproduction CREB1;CREBBP GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;CREBBP GO:0006355| regulation of transcription, DNA-dependent CREB1;CREBBP;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;CREBBP 8284:[DB01183 DB02360] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways GO:0071222| cellular response to lipopolysaccharide CTSG;TLR4;OPRK1 GO:0050829| defense response to Gram-negative bacterium CTSG;TLR4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CTSG GO:0006955| immune response TLR4;OPRK1;OPRD1;CTSG GO:0042742| defense response to bacterium CTSG;TLR4 GO:0006468| protein phosphorylation CTSG;CREB1 GO:0044267| cellular protein metabolic process CTSG;ALB 8285:[DB01183 DB07053] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;PPARG;CREB1;ESR1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm CREB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0042493| response to drug UGT1A1;CREB1;PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;PPARG;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRD1;OPRM1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process CREB1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG 8286:[DB01183 DB01251] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;ABCC8;ESR1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1;CYP2C9 GO:0097267| CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0007613| memory ABCC8;CREB1 GO:0006811| ion transport SLCO1A2;KCNJ8 GO:0055085| transmembrane transport ABCB1;ABCC8;SLCO1A2 GO:0032868| response to insulin stimulus ABCC8;OPRK1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ABCC8;OPRM1;KCNJ8 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0032760| positive regulation of tumor necrosis factor production ABCC8;TLR4 GO:0008542| visual learning CREB1;ABCC8 GO:0051607| defense response to virus KCNJ8;OPRK1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCC8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 8287:[DB01183 DB04942] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways GO:0032720| negative regulation of tumor necrosis factor production RARA;TLR4 GO:0032689| negative regulation of interferon-gamma production RARA;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;CRABP1;ESR1;RARA;TLR4;CREB1;RARB;OPRK1 GO:0032355| response to estradiol stimulus RARA;ESR1 GO:0006468| protein phosphorylation CREB1;RARA GO:0008584| male gonad development RARA;ESR1 GO:0010628| positive regulation of gene expression RARA;TLR4 GO:0008285| negative regulation of cell proliferation RARA;OPRM1;RARB GO:0043065| positive regulation of apoptotic process RARB;CREB1 GO:0071222| cellular response to lipopolysaccharide RARA;TLR4;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;ESR1;RARB;CREB1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;RARB;RARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARA;RARB GO:0042981| regulation of apoptotic process CREB1;ESR1;RARA GO:0045471| response to ethanol RARA;OPRM1;OPRK1;UGT1A1 GO:0043401| steroid hormone mediated signaling pathway RARB;RARA;ESR1 GO:0001889| liver development RARA;UGT1A1 GO:0006351| transcription, DNA-dependent ESR1;RARA;CREB1;RARB GO:0071391| cellular response to estrogen stimulus RARA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARA;RARB GO:0010629| negative regulation of gene expression OPRD1;ESR1;RARA;CREB1 GO:0006355| regulation of transcription, DNA-dependent RARA;ESR1;RARB;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;RARA;ESR1 8288:[DB01183 DB00735] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00735|Naftifine SQLE common genes common pathways GO:0010033| response to organic substance UGT1A1;CREB1;SQLE GO:0006695| cholesterol biosynthetic process SQLE;CES1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;SQLE 8289:[DB01183 DB02846] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02846|L-thioproline ANXA5 common genes common pathways GO:0043086| negative regulation of catalytic activity UGT1A1;ANXA5 GO:0043066| negative regulation of apoptotic process ALB;ANXA5 GO:0002576| platelet degranulation ALB;ANXA5 GO:0010033| response to organic substance ANXA5;CREB1;UGT1A1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;ANXA5;TLR4;CREB1;OPRK1 8290:[DB01183 DB03673] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03673|Beta(2-Thienyl)Alanine PAH common genes common pathways GO:0055114| oxidation-reduction process PAH;CYP2C8;CYP3A4 GO:0008152| metabolic process PAH;UGT1A1;CES1 8291:[DB01183 DB04867] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04867|Lintitript CCKAR common genes common pathways GO:0007586| digestion UGT1A1;CCKAR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;CCKAR;ESR1;OPRM1;OPRD1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4;CCKAR GO:0032870| cellular response to hormone stimulus CCKAR;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration CCKAR;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;CCKAR GO:0007584| response to nutrient CCKAR;UGT1A1 GO:0007409| axonogenesis CCKAR;CREB1 8292:[DB01183 DB00770] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;PTGER1;ESR1;PTGER2;PTGDR2 GO:0015711| organic anion transport SLCO1A2;SLC22A6;ABCC5 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO3A1;ALB;SLCO2B1;SLCO2A1;SLC22A6 GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;PTGER2;OPRD1;PTGER1;OPRM1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway PTGDR2;OPRD1;OPRM1;OPRK1 GO:0006810| transport ABCB1;ABCC5 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1A2 GO:0010033| response to organic substance UGT1A1;CREB1;ABCC4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;PTGDR2 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0006811| ion transport SLCO2B1;SLCO3A1;SLCO1A2 GO:0055085| transmembrane transport ABCC4;SLCO1A2;SLCO3A1;ABCC5;SLCO2B1;ABCB1;SLCO2A1;SLC22A6 GO:0002576| platelet degranulation ABCC4;ALB GO:0007218| neuropeptide signaling pathway PTGDR2;OPRD1;OPRM1;OPRK1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;PTGER1;PTGER2 GO:0006955| immune response OPRK1;TLR4;PTGDR2;OPRD1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCC4 GO:0007268| synaptic transmission OPRK1;PTGDR2;OPRD1;OPRM1 GO:0055114| oxidation-reduction process CYP3A4;ABCC4;CYP2C8 8293:[DB01183 DB05956] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0006810| transport GRIN2B;ABCB1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;RXRA GO:0006811| ion transport GRIN2B;SLCO1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;RXRA;TLR4;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA GO:0045471| response to ethanol GRIN2B;OPRM1;UGT1A1;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2B;OPRM1 GO:0043401| steroid hormone mediated signaling pathway ESR1;RXRA GO:0006351| transcription, DNA-dependent RXRA;CREB1;ESR1 GO:0016032| viral reproduction RXRA;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0007268| synaptic transmission OPRK1;GRIN2B;OPRM1;OPRD1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;RXRA GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;RXRA 8294:[DB01183 DB04967] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0016032| viral reproduction CREB1;TOP1 GO:0055114| oxidation-reduction process CYP2C8;APEX1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent APEX1;CREB1;ESR1 GO:0042493| response to drug APEX1;ABCB1;UGT1A1;CREB1;TOP1 GO:0042981| regulation of apoptotic process APEX1;CREB1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TOP2A;TLR4 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;APEX1 GO:0007623| circadian rhythm TOP1;CREB1 GO:0048511| rhythmic process TOP1;TOP2A;CREB1 GO:0006338| chromatin remodeling TOP1;ESR1 GO:0007568| aging CREB1;APEX1 8295:[DB01183 DB07422] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006351| transcription, DNA-dependent CREB1;ESR1;AR GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;TLR4;CREB1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0006810| transport ABCB1;AR GO:0007165| signal transduction ESR1;OPRD1;OPRM1;AR;TLR4;CREB1;OPRK1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0008584| male gonad development ESR1;AR GO:0016579| protein deubiquitination AR;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR 8296:[DB01183 DB06094] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06094|Apatorsen HSPB1 common genes common pathways GO:0001895| retina homeostasis ALB;HSPB1 GO:0043066| negative regulation of apoptotic process ALB;HSPB1 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process HSPB1;TLR4 8297:[DB01183 DB05390] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05390|INS 316 P2RY2 common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;P2RY2;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway P2RY2;OPRD1;OPRM1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger P2RY2;ESR1;OPRD1;OPRM1;OPRK1 8298:[DB01183 DB04974] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04974|AP1903 MTOR common genes common pathways GO:0032868| response to insulin stimulus OPRK1;MTOR GO:0050769| positive regulation of neurogenesis MTOR;OPRM1 GO:0042220| response to cocaine OPRK1;MTOR;OPRM1 GO:0007584| response to nutrient UGT1A1;MTOR GO:0010628| positive regulation of gene expression TLR4;MTOR GO:0006468| protein phosphorylation MTOR;CREB1 GO:0071456| cellular response to hypoxia MTOR;OPRD1 GO:0009267| cellular response to starvation MTOR;ALB GO:0007165| signal transduction OPRK1;MTOR;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;MTOR;TLR4 GO:0008361| regulation of cell size MTOR;CREB1 GO:0008542| visual learning MTOR;CREB1 GO:0043278| response to morphine MTOR;OPRK1;OPRM1 GO:0042060| wound healing MTOR;OPRM1 GO:0046889| positive regulation of lipid biosynthetic process MTOR;CREB1 8299:[DB01183 DB00417] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0006810| transport ABCB1;SLC15A1 GO:0006811| ion transport SLCO1A2;SLC15A1 GO:0055085| transmembrane transport SLCO1A2;SLC15A1;ABCB1 GO:0007586| digestion SLC15A1;UGT1A1 8300:[DB01183 DB02234] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02234|S-Ethylisothiourea NOS2;NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0032496| response to lipopolysaccharide UGT1A1;NOS2;TLR4;OPRM1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP3A4;NOS3;CYP2C8;NOS2 GO:0009617| response to bacterium TLR4;NOS2 GO:0001666| response to hypoxia CREB1;NOS2 GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 8301:[DB01183 DB04471] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes ESR1 common pathways GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0060065| uterus development ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;OPRK1 8302:[DB01183 DB06885] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0044267| cellular protein metabolic process TTR;ALB 8303:[DB01183 DB02263] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB;SLCO2A1 GO:0055085| transmembrane transport SLCO2A1;ABCB1;SLCO1A2 8304:[DB01183 DB03072] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03072|2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone PARP1 common genes common pathways GO:1904646| TLR4;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;PARP1 GO:0006366| transcription from RNA polymerase II promoter PARP1;ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PARP1;CREB1;TLR4 GO:0006351| transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PARP1 8305:[DB01183 DB06311] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06311|Darapladib PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;CYP3A4 GO:0008152| metabolic process CES1;UGT1A1;PLA2G4A 8306:[DB01183 DB02696] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways GO:0002064| epithelial cell development B4GALT1;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;B4GALT1 GO:0030879| mammary gland development CREB1;B4GALT1 GO:0043065| positive regulation of apoptotic process CREB1;B4GALT1 GO:0042060| wound healing B4GALT1;OPRM1 8307:[DB01183 DB08121] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0042493| response to drug CREB1;PPARG;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;CREB1;TLR4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance PPARG;CREB1;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0048511| rhythmic process CREB1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1;PPARG 8308:[DB01183 DB03192] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1;HSD17B4 GO:0055114| oxidation-reduction process HSD17B4;CYP2C8;CYP3A4 GO:0008210| estrogen metabolic process HSD17B4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;HSD17B4 8309:[DB01183 DB14515] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14515|Magnesium lactate ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:0042493| response to drug ATP1A1;ABCB1;UGT1A1;CREB1 GO:0006811| ion transport ATP1A1;SLCO1A2 8310:[DB01183 DB06985] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways GO:0060068| vagina development RBP4;ESR1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;RBP4 GO:0060065| uterus development ESR1;RBP4 8311:[DB01183 DB03405] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03405|N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 8312:[DB01183 DB08550] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08550|7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline PNMT common genes common pathways 8313:[DB01183 DB03267] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0014823| response to activity PCK1;CREB1 GO:0032868| response to insulin stimulus PCK1;OPRK1 GO:0071456| cellular response to hypoxia OPRD1;PCK1 GO:0007568| aging PCK1;CREB1 GO:0006629| lipid metabolic process PCK1;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;PCK1;OPRM1 8314:[DB01183 DB00536] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00536|Guanidine argG;GAMT;RNASE1;DLG4;ALDH2;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A8;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration DLG4;ESR1;OPRM1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A8;SLCO1A2 GO:0015711| organic anion transport SLC22A3;SLC22A4;SLCO1A2;SLC22A5;SLC22A2;SLC22A1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;DLG4;OPRM1;OPRD1 GO:0055085| transmembrane transport SLC47A2;SLC47A1;DLG4;SLC22A5;SLC22A8;SLC22A3;SLCO1A2;SLC22A4;SLC22A2;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC22A1;SLC47A1;SLC47A2;SLC22A3;SLC22A5 GO:0009636| response to toxin CES1;SLC22A8 GO:0006811| ion transport SLC22A8;SLC22A5;SLC22A4;SLCO1A2;SLC22A3;SLC22A2;SLC22A1 GO:0008152| metabolic process ALDH2;CES1;UGT1A1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;DLG4 GO:0055114| oxidation-reduction process CYP2C8;ALDH2;CYP3A4 GO:0051607| defense response to virus OPRK1;RNASE1 GO:0007268| synaptic transmission DLG4;OPRD1;OPRM1;OPRK1 8315:[DB01183 DB12569] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12569|Tonapofylline ADORA1 common genes common pathways GO:0006954| inflammatory response TLR4;ADORA1 GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA1;OPRM1 GO:0097190| apoptotic signaling pathway ADORA1;TLR4 GO:0008285| negative regulation of cell proliferation ADORA1;OPRM1 GO:0001666| response to hypoxia CREB1;ADORA1 GO:0051930| regulation of sensory perception of pain ADORA1;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction CREB1;ADORA1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADORA1;OPRK1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADORA1;OPRK1;OPRD1;OPRM1 8316:[DB01183 DB00882] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes ABCB1;ESR1 common pathways GO:1903799| ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;UGT1A1;CYP1A1;CYP2C8 GO:0097267| CYP1A2;CYP2C8;CYP1A1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0002064| epithelial cell development ESR1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP2C8;CYP1A2;CYP11A1;CYP3A4;CYP2E1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0007568| aging CREB1;CYP1A1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0042359| vitamin D metabolic process CYP1A1;CYP11A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0010033| response to organic substance CYP1A2;CREB1;CYP1A1;UGT1A1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0009636| response to toxin CYP1A1;CES1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8;CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CES1;CYP1A2;CYP2C8 GO:0060065| uterus development ESR1;CYP19A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP11A1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4;CYP1A1 GO:1901529| ABCB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0045471| response to ethanol OPRM1;CYP2E1;UGT1A1;OPRK1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CREB1;CYP1A1;UGT1A1;ABCB1;CYP2E1;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0032094| response to food CYP1A1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0055114| oxidation-reduction process CYP19A1;CYP1A1;CYP2C8;CYP1A2;CYP11A1;CYP3A4;CYP2E1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 8317:[DB01183 DB07234] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways GO:0002224| toll-like receptor signaling pathway MAPKAPK2;TLR4 GO:0006468| protein phosphorylation MAPKAPK2;CREB1 GO:0000187| activation of MAPK activity MAPKAPK2;TLR4 GO:0032496| response to lipopolysaccharide MAPKAPK2;UGT1A1;TLR4;OPRM1 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process TLR4;MAPKAPK2 GO:0006954| inflammatory response MAPKAPK2;TLR4 8318:[DB01183 DB05284] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05284|CA4P TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 8319:[DB01183 DB08498] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0035094| response to nicotine CASP3;CREB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CASP3 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;CREB1 GO:0042060| wound healing OPRM1;CASP3 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CASP3 GO:0097190| apoptotic signaling pathway TLR4;CASP3 GO:0001666| response to hypoxia CASP3;CREB1 GO:0010033| response to organic substance UGT1A1;CREB1;CASP3 GO:0014070| response to organic cyclic compound CASP3;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0032355| response to estradiol stimulus ESR1;CASP3 8320:[DB01183 DB01969] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 8321:[DB01183 DB00172] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0050821| protein stabilization PPIB;P3H1;CREB1 GO:0006810| transport SLC6A7;ABCB1;SLC6A14 GO:0040018| positive regulation of multicellular organism growth PPIB;CREB1 GO:0009636| response to toxin SLC6A14;CES1 GO:0055085| transmembrane transport SLC6A14;SLC16A10;SLCO1A2;ABCB1 GO:0051881| regulation of mitochondrial membrane potential PYCR1;OPRD1 GO:0008285| negative regulation of cell proliferation P3H2;OPRM1;P3H3;P3H1 GO:0043066| negative regulation of apoptotic process PPIF;ALB GO:0008152| metabolic process CES1;UGT1A1;EPRS GO:0042981| regulation of apoptotic process PPIF;ESR1;CREB1 GO:0070266| necroptosis TLR4;PPIF GO:0055114| oxidation-reduction process PYCR1;P3H2;PYCR2;P4HA2;P3H3;CYP3A4;PRODH;P4HA1;P3H1;CYP2C8 GO:0016032| viral reproduction CREB1;PPIA 8322:[DB01183 DB01989] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways GO:0030154| cell differentiation CREB1;TLL2 8323:[DB01183 DB00269] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes ESR1 common pathways GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP19A1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0060065| uterus development ESR1;CYP19A1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;OPRK1 8324:[DB01183 DB07906] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07906|[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL PNMT common genes common pathways 8325:[DB01183 DB02419] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways GO:0016032| viral reproduction PPIA;CREB1 8326:[DB01183 DB12128] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12128|Ulimorelin GHSR common genes common pathways GO:0007165| signal transduction OPRK1;GHSR;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;GHSR;OPRK1 GO:0032355| response to estradiol stimulus GHSR;ESR1 GO:1990314| GHSR;CREB1 GO:0040018| positive regulation of multicellular organism growth GHSR;CREB1 GO:0032100| positive regulation of appetite OPRM1;GHSR GO:0032094| response to food GHSR;OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;GHSR;TLR4 8327:[DB01183 DB07405] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0010629| negative regulation of gene expression ESR1;OPRD1;NOS2;CREB1 GO:0009617| response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0007623| circadian rhythm CREB1;NOS2 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;NOS2;TLR4 8328:[DB01183 DB08746] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08746|1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE F10 common genes common pathways 8329:[DB01183 DB00711] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CES1;CYP3A4 GO:0006954| inflammatory response TLR4;PTGS1;ALOX5 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS1;ALOX5 GO:0042493| response to drug ABCB1;CREB1;BCHE;UGT1A1 GO:0098869| PTGS1;ALB GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE 8330:[DB01183 DB07627] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07627|(2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE CAPN1 common genes common pathways 8331:[DB01183 DB05420] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0008584| male gonad development RRM1;ESR1 GO:0008152| metabolic process CES1;UGT1A1;RRM1 GO:0055114| oxidation-reduction process RRM1;CYP2C8;CYP3A4 8332:[DB01183 DB03187] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 8333:[DB01183 DB07329] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07329|1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID IGHG2 common genes common pathways GO:0002376| immune system process TLR4;IGHG2 GO:0042742| defense response to bacterium TLR4;IGHG2 GO:0045087| innate immune response IGHG2;TLR4 8334:[DB01183 DB05798] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PRKAR1A;ESR1 8335:[DB01183 DB07733] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CASP1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;TLR4 GO:0050727| regulation of inflammatory response TLR4;CASP1;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;CASP1;OPRK1 GO:0071260| cellular response to mechanical stimulus CASP1;TLR4 GO:0042981| regulation of apoptotic process ESR1;CREB1;CASP1 GO:0009617| response to bacterium CASP1;TLR4 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;CASP1 GO:0007165| signal transduction OPRK1;CREB1;CASP1;TLR4;OPRM1;OPRD1;ESR1 GO:0001666| response to hypoxia CASP1;CREB1 8336:[DB01183 DB14012] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14012|Burosumab FGF23 common genes common pathways GO:0030154| cell differentiation FGF23;CREB1 GO:0042359| vitamin D metabolic process FGF23;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;FGF23;TLR4 GO:0044267| cellular protein metabolic process ALB;FGF23 GO:0043687| post-translational protein modification ALB;FGF23 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;FGF23;ESR1 8337:[DB01183 DB07978] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation DHODH;UGT1A1 GO:0042493| response to drug DHODH;ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHODH GO:0007595| lactation DHODH;CREB1 8338:[DB01183 DB11300] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11300|Thrombin F2R;F2RL3;F11;F13A1;F13B;FGA;FGB;FGG;F5;F8 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway F2R;OPRM1;OPRD1;F2RL3;OPRK1 GO:0002224| toll-like receptor signaling pathway TLR4;FGG;FGA;FGB GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;F2R GO:0002376| immune system process FGB;TLR4;FGA GO:0007165| signal transduction F2RL3;CREB1;TLR4;FGG;OPRK1;FGA;F2R;ESR1;OPRM1;OPRD1;FGB GO:0051930| regulation of sensory perception of pain OPRK1;F2R;OPRM1;OPRD1 GO:0044267| cellular protein metabolic process FGA;F5;ALB;FGG GO:0070374| positive regulation of ERK1 and ERK2 cascade FGB;OPRM1;F2R;FGA;FGG;TLR4 GO:0008285| negative regulation of cell proliferation F2R;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;F2R GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;F2R;ESR1;F2RL3;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade F2R;TLR4 GO:0002576| platelet degranulation FGG;F8;F13A1;ALB;F5;FGA;FGB GO:0045087| innate immune response TLR4;FGA;FGB GO:0045893| positive regulation of transcription, DNA-dependent CREB1;F2R;ESR1 GO:0043687| post-translational protein modification ALB;FGA;F5;FGG GO:0055114| oxidation-reduction process F8;CYP2C8;CYP3A4 GO:0006954| inflammatory response TLR4;F2R GO:0006953| acute-phase response UGT1A1;F8 8339:[DB01183 DB05025] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0007568| aging CREB1;SOD1 GO:0000187| activation of MAPK activity SOD1;TLR4 GO:0001895| retina homeostasis SOD1;ALB GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0010033| response to organic substance CREB1;UGT1A1;SOD1 GO:0045471| response to ethanol UGT1A1;OPRK1;SOD1;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;SOD1 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0043065| positive regulation of apoptotic process CREB1;SOD1 GO:0002576| platelet degranulation ALB;SOD1 GO:0042493| response to drug SOD1;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process SOD1;CYP3A4;CYP2C8 8340:[DB01183 DB06245] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;FGA;PLAUR;OPRK1;OPRM1;OPRD1;ESR1 GO:0006898| receptor-mediated endocytosis ALB;LRP1;CALR GO:0002376| immune system process TLR4;FGA GO:0007568| aging CREB1;LRP1;CANX GO:0002224| toll-like receptor signaling pathway FGA;TLR4 GO:0030154| cell differentiation LAMA5;CREB1 GO:0032355| response to estradiol stimulus CALR;ESR1 GO:0050821| protein stabilization CALR;CREB1 GO:0010033| response to organic substance CALR;CREB1;UGT1A1 GO:1904646| LRP1;TLR4 GO:0010628| positive regulation of gene expression CALR;FN1;TLR4 GO:0048146| positive regulation of fibroblast proliferation FN1;ESR1;ANXA2 GO:0044267| cellular protein metabolic process FN1;LAMB1;ALB;FGA;LAMC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;FGA;TLR4 GO:0006629| lipid metabolic process LRP1;CYP3A4 GO:0045087| innate immune response TLR4;FGA GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1 GO:0042981| regulation of apoptotic process ESR1;CALR;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;CLEC3B GO:0043066| negative regulation of apoptotic process SERPINB2;ALB;PLAUR GO:0002576| platelet degranulation FGA;CLEC3B;ALB;FN1 GO:0042060| wound healing OPRM1;SERPINB2;FN1 GO:0006953| acute-phase response UGT1A1;FN1 GO:0016032| viral reproduction CREB1;KRT8 GO:0043687| post-translational protein modification FN1;FGA;LAMB1;ALB;LAMC1 GO:0043086| negative regulation of catalytic activity ANXA2;UGT1A1 GO:0042493| response to drug UGT1A1;CALR;CREB1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent CALR;CREB1;ESR1 8341:[DB01183 DB02510] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02510|'5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine EPRS common genes common pathways GO:0008152| metabolic process UGT1A1;EPRS;CES1 8342:[DB01183 DB05424] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05424|Canertinib EGFR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;CREB1;TLR4;ESR1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0042060| wound healing OPRM1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1 GO:0007623| circadian rhythm CREB1;EGFR GO:0001889| liver development EGFR;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;EGFR;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;EGFR GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;EGFR GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;EGFR GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0050729| positive regulation of inflammatory response EGFR;TLR4 GO:0006468| protein phosphorylation EGFR;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;EGFR;OPRM1 8343:[DB01183 DB05219] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes CYP2C8 common pathways GO:0002933| CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9;CYP2B6;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway PDE4C;PDE4B;OPRK1;OPRM1;PDE4D;PDE4A;OPRD1 GO:0007568| aging CREB1;PDE4D GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2B6;CYP2C9;CYP2C8 GO:0007165| signal transduction ESR1;PDE4A;OPRD1;PDE4D;OPRM1;TLR4;CREB1;OPRK1;PDE4C;PDE4B GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9;CYP2B6 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C8;CYP3A4 GO:0032729| positive regulation of interferon-gamma production PDE4D;PDE4B;TLR4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;CYP2C8;CYP3A4;CES1 GO:0071222| cellular response to lipopolysaccharide TLR4;PDE4B;OPRK1;PDE4D GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006082| organic acid metabolic process CYP2C8 8344:[DB01183 DB00890] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00890|Dienestrol ESR1;SHBG common genes ESR1 common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0032355| response to estradiol stimulus ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060065| uterus development ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 8345:[DB01183 DB05469] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ADRA1A;TLR4 GO:0007165| signal transduction ADRA1A;OPRK1;ADRA1D;TLR4;CREB1;ADRA1B;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;OPRM1;OPRD1;OPRK1;ADRA1A;ADRA1D GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;OPRM1;ESR1;ADRA1A;ADRA1D GO:0007568| aging CREB1;ADRA1A GO:0042493| response to drug ADRA1A;ABCB1;CREB1;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1D;OPRK1;ADRA1A;ESR1;OPRM1;OPRD1;ADRA1B 8346:[DB01183 DB03003] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03003|Glutathione Sulfonic Acid gstA;GSTM4;GSTA1;GSTP1 common genes common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;GSTP1 GO:0045471| response to ethanol OPRM1;UGT1A1;GSTP1;OPRK1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0008152| metabolic process GSTM4;CES1;GSTA1;GSTP1;UGT1A1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;CES1;CYP3A4 GO:0071222| cellular response to lipopolysaccharide GSTP1;OPRK1;TLR4 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0032355| response to estradiol stimulus ESR1;GSTP1 GO:0098869| ALB;GSTP1;GSTA1 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0009636| response to toxin CES1;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0030855| epithelial cell differentiation CES1;GSTA1 8347:[DB01183 DB02750] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways GO:0009636| response to toxin CES1;SLC7A8 GO:0030154| cell differentiation CREB1;SLC7A5 GO:0006810| transport SLC7A8;SLC7A5;ABCB1 8348:[DB01183 DB11638] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes ALB common pathways GO:0042981| regulation of apoptotic process LGALS1;ESR1;CREB1 GO:0045087| innate immune response TLR4;SFPQ GO:0000122| negative regulation of transcription from RNA polymerase II promoter DDX5;HNRNPA2B1;SFPQ;ENO1;ESR1;RPL10 GO:0006629| lipid metabolic process UGT2B7;CYP3A4;G6PD;CYP2D6 GO:0030520| intracellular estrogen receptor signaling pathway DDX5;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;HNRNPK;TLR4;NPM1;SFPQ;ESR1 GO:0050829| defense response to Gram-negative bacterium TLR4;RPS19 GO:0043065| positive regulation of apoptotic process LDHA;CREB1;RPS6 GO:0002576| platelet degranulation FLNA;ALDOA;ALB;TAGLN2 GO:0050727| regulation of inflammatory response ESR1;ZYX;TLR4 GO:0043066| negative regulation of apoptotic process FLNA;HNRNPK;NPM1;HSPB1;ALB;RPS6;CFL1;RPL10 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2D6;CYP2C8;CYP2C19;CYP3A4;CES1 GO:0008152| metabolic process CES1;TPI1;PKM;UGT2B7;PGAM1;UGT1A1;UGT1A9;ALDH7A1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FLNA;LGALS1 GO:1904224| UGT1A1;UGT1A9 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;G6PD GO:0006351| transcription, DNA-dependent HSPA8;DDX5;EEF1A1;HNRNPK;CREB1;SF1;ENO1;SFPQ;ESR1;HNRNPD;KHSRP GO:0001889| liver development DDX39B;HNRNPD;PKM;UGT1A1 GO:0006695| cholesterol biosynthetic process G6PD;CES1 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2D6;CYP3A4 GO:0042060| wound healing OPRM1;TPM1;DSP GO:0006357| regulation of transcription from RNA polymerase II promoter NPM1;HNRNPK;DDX5;PFN1;ESR1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process HSPB1;TLR4 GO:0042752| regulation of circadian rhythm HNRNPD;CREB1;SFPQ GO:0043278| response to morphine OPRM1;OPRK1;GPI GO:0051092| positive regulation of NF-kappaB transcription factor activity NPM1;TLR4 GO:0016032| viral reproduction VIM;CREB1;PPIA;HNRNPK;HSPA8;NPM1;ZYX GO:0008209| androgen metabolic process CYP3A4;ESR1;UGT2B7 GO:0002218| activation of innate immune response TLR4;SFPQ GO:0055114| oxidation-reduction process GAPDHS;LDHA;FTO;CYP2C8;CYP2C19;CYP2D6;ALDH7A1;PRDX1;LDHB;G6PD;GAPDH;CYP3A4;CYCS;P4HB;MDH1 GO:0043687| post-translational protein modification ALB;LGALS1;P4HB GO:0052695| cellular glucuronidation UGT1A9;UGT1A1;UGT2B7 GO:0006355| regulation of transcription, DNA-dependent CREB1;HNRNPK;EEF1A1;DDX5;HSPA8;SFPQ;ENO1;SF1;ESR1;HP1BP3;KHSRP;HNRNPD GO:0042493| response to drug LGALS1;HNRNPD;SRP14;ABCB1;LDHA;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0010629| negative regulation of gene expression OPRD1;ESR1;HNRNPD;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;HNRNPD;NPM1;CREB1 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0043086| negative regulation of catalytic activity ANXA2;UGT1A1 GO:0032094| response to food G6PD;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;LGALS1;CLIC1;NPM1;TLR4;HNRNPK;CREB1;ZYX;IQGAP1;DPYSL2;OPRK1 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process UGT1A9;UGT1A1;CYP2D6;CYP2C8;CYP2C19;CYP3A4 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;KHSRP GO:0070989| oxidative demethylation CYP3A4;FTO;CYP2C8;CYP2D6 GO:0031100| organ regeneration UGT1A1;PKM GO:0002376| immune system process TLR4;SFPQ GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0071456| cellular response to hypoxia OPRD1;HP1BP3;P4HB;PGK1;NPEPPS GO:0030154| cell differentiation DPYSL2;CREB1 GO:0071392| cellular response to estradiol stimulus UGT1A1;HNRNPD;ESR1 GO:0006468| protein phosphorylation CFL1;CREB1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0014002| astrocyte development VIM;TLR4 GO:1901381| OPRK1;FLNA GO:0050821| protein stabilization GAPDH;PFN1;FLNA;CREB1;CCT3 GO:0036120| IQGAP1;CREB1 GO:0032355| response to estradiol stimulus GPI;HNRNPD;ESR1 GO:0008202| steroid metabolic process CYP3A4;UGT2B7;UGT1A1;CYP2C8;CYP2C19;CYP2D6 GO:0009267| cellular response to starvation ALB;HSPA8 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0007411| axon guidance DPYSL2;CREB1 GO:0048511| rhythmic process SFPQ;DDX5;CREB1;HNRNPD GO:0007584| response to nutrient LDHA;UGT1A1;PKM GO:0043627| response to estrogen stimulus ESR1;LDHA;OPRK1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;FLNA GO:0008285| negative regulation of cell proliferation OPRM1;NPM1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9 GO:0010033| response to organic substance CREB1;UGT1A1;PKM GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0048146| positive regulation of fibroblast proliferation ESR1;ANXA2 GO:0010628| positive regulation of gene expression VIM;HNRNPD;TLR4 GO:0001666| response to hypoxia PKM;CREB1;LDHA GO:0051881| regulation of mitochondrial membrane potential CLIC1;OPRD1 GO:0000086| G2/M transition of mitotic cell cycle TUBB4A;ABCB1;TUBA1A;TUBB GO:0032868| response to insulin stimulus PKM;SRSF4;OPRK1 GO:0006366| transcription from RNA polymerase II promoter NPM1;CREB1;HNRNPK;ESR1 GO:0044267| cellular protein metabolic process ALB;P4HB;LGALS1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;ZYX GO:0030855| epithelial cell differentiation TAGLN2;CES1;PGK1 GO:0001895| retina homeostasis HSPB1;PRDX1;ALB;ACTG1 GO:0006811| ion transport SLCO1A2;CLIC1;ATP5O;ATP5L GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0014070| response to organic cyclic compound UGT1A1;LDHA;G6PD GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9 GO:0034375| high-density lipoprotein particle remodeling ALB 8349:[DB01183 DB01161] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;HTR3A;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007568| aging CREB1;SLC6A3 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;ESR1;OPRM1 GO:0070588| calcium ion transmembrane transport OPRM1;GRIN3A;CHRNA10 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;HTR3A;CHRNA10;OPRK1 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0006811| ion transport SLCO1A2;HTR3A;CHRNA10;SCN10A;GRIN3A GO:0042220| response to cocaine OPRM1;SLC6A3;OPRK1;HTR3A GO:0055085| transmembrane transport SLCO1A2;SLC6A3;ABCB1;SCN10A GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0019233| sensory perception of pain OPRK1;SCN10A;OPRD1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN3A;CHRNA10;OPRM1 GO:0045471| response to ethanol OPRM1;SLC6A3;OPRK1;HTR3A;GRIN3A;UGT1A1 GO:0007626| locomotory behavior OPRM1;SLC6A3;OPRK1 GO:0042493| response to drug UGT1A1;BCHE;CREB1;ABCB1;SLC6A3 GO:0007268| synaptic transmission OPRM1;OPRD1;HTR3A;OPRK1 GO:0035094| response to nicotine SLC6A3;CREB1 GO:0007600| sensory perception OPRM1;OPRK1;SCN10A GO:0007595| lactation CREB1;SLC6A3 8350:[DB01183 DB01870] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01870|1,4-dithio-alpha-D-glucopyranose AMY2B common genes common pathways GO:0008152| metabolic process CES1;AMY2B;UGT1A1 GO:0007586| digestion UGT1A1;AMY2B 8351:[DB01183 DB07374] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0050821| protein stabilization RPL11;CREB1;RPL23 GO:0010628| positive regulation of gene expression RPL11;TLR4;RPL23 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;RPL23;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RPL23 GO:0045471| response to ethanol OPRM1;UGT1A1;RPL15;OPRK1 8352:[DB01183 DB04882] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04882|Edotecarin TOP1 common genes common pathways GO:0007623| circadian rhythm CREB1;TOP1 GO:0042493| response to drug TOP1;UGT1A1;CREB1;ABCB1 GO:0016032| viral reproduction TOP1;CREB1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process CREB1;TOP1 8353:[DB01183 DB14637] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14637|Fluprednisolone acetate CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 8354:[DB01183 DB06451] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06451|Aprinocarsen PRKCA common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade PRKCA;TLR4;OPRM1 GO:0007411| axon guidance PRKCA;CREB1 GO:0006468| protein phosphorylation PRKCA;CREB1 GO:0097190| apoptotic signaling pathway TLR4;PRKCA 8355:[DB01183 DB00228] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0006811| ion transport KCNN4;GABRG1;GABRA3;GABRA5;GABRD;GABRB2;GLRA1;GABRP;GLRB;KCNA1;GRIA1;GABRA2;GABRE;GABRQ;GABRB1;GABRG2;SLCO1A2;GABRA4;GABRA6;GABRA1;ATP2C1;GABRB3;GABRG3 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0009636| response to toxin CES1;GABRB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;KCNA1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0002376| immune system process KCNN4;TLR4 GO:0006898| receptor-mediated endocytosis ALB GO:0070588| calcium ion transmembrane transport ATP2C1;OPRM1 GO:0098869| ALB GO:0007165| signal transduction GABRA5;TLR4;GABRP;CREB1;GABRD;GRIA1;OPRK1;GABRQ;GABRB1;OPRD1;GABRE;OPRM1;ESR1;GABRA6;ATP2C1;GABRB3 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP2E1 GO:0051659| maintenance of mitochondrion location ALB GO:0009267| cellular response to starvation ALB GO:0045332| phospholipid translocation KCNN4;ABCB1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2C8 GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport ABCB1;GABRA5;GABRA3;GABRD;GABRB2;GABRB3;GABRG2;GABRB1;GABRA6;GABRA4;GABRA1 GO:0042493| response to drug CYP2E1;GABRG3;UGT1A1;CREB1;ABCB1 GO:0007268| synaptic transmission GABRA5;GABRG1;GLRA1;GABRD;GABRB2;GRIA1;KCNA1;GLRB;OPRK1;OPRD1;GABRG2;OPRM1 GO:1901215| GABRB3;GABRB2;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0007218| neuropeptide signaling pathway OPRK1;GLRB;GLRA1;OPRD1;OPRM1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2E1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0071294| cellular response to zinc ion CREB1;GLRA1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;CYP2E1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA1;GRIA1;GLRB 8356:[DB01183 DB07207] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways GO:0031100| organ regeneration F7;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;F7 GO:0043627| response to estrogen stimulus F7;OPRK1;ESR1 GO:0001666| response to hypoxia F7;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;F7 GO:0007623| circadian rhythm F7;CREB1 8357:[DB01183 DB08547] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08547|PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0045087| innate immune response IGHG2;TLR4 GO:0042742| defense response to bacterium TLR4;IGHG2 GO:0002376| immune system process IGHG2;TLR4 8358:[DB01183 DB07488] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07488|{(2Z)-4-AMINO-2-[(4-METHOXYPHENYL)IMINO]-2,3-DIHYDRO-1,3-THIAZOL-5-YL}(4-METHOXYPHENYL)METHANONE CSNK1G3 common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;CSNK1G3;ESR1;OPRD1;OPRM1 GO:0006468| protein phosphorylation CSNK1G3;CREB1 8359:[DB01183 DB00663] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;TLR4;CREB1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0006351| transcription, DNA-dependent CREB1;NR3C1;ESR1 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;NR3C1;CREB1;TLR4;OPRK1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 8360:[DB01183 DB00801] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006811| ion transport GABRR3;GABRG3;GABRB3;SLCO1A2;GABRG2;GABRB1;GABRQ;GABRE;GABRA1;GABRA4;GABRA6;GABRR1;GABRA2;GABRA5;GABRA3;GABRR2;GABRG1;GABRP;GABRB2;GABRD GO:0009636| response to toxin GABRB1;CES1 GO:0006810| transport ABCB1;GABRR2;GABRA3;GABRA5;GABRD;GABRB2;GABRB3;GABRG2;GABRB1;GABRA4;GABRR1;GABRA6;GABRA1 GO:0007165| signal transduction GABRA5;GABRR2;TLR4;GABRP;CREB1;GABRD;OPRK1;GABRQ;OPRD1;GABRB1;OPRM1;GABRE;ESR1;GABRA6;GABRB3 GO:0042493| response to drug GABRG3;ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission GABRR1;OPRM1;GABRG2;OPRD1;GABRR3;GABRD;GABRB2;GABRG1;GABRR2;GABRA5;OPRK1 GO:1901215| CREB1;GABRB2;GABRB3 8361:[DB01183 DB01282] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01282|Carbetocin OXTR common genes common pathways GO:0042493| response to drug OXTR;UGT1A1;CREB1;ABCB1 GO:0042711| maternal behavior OPRK1;OXTR GO:0007595| lactation OXTR;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OXTR;OPRK1 GO:0032355| response to estradiol stimulus ESR1;OXTR GO:0007204| elevation of cytosolic calcium ion concentration OXTR;ESR1;OPRM1 GO:0007613| memory OXTR;CREB1 GO:0032870| cellular response to hormone stimulus UGT1A1;OXTR GO:0044849| OPRM1;OXTR;OPRK1 GO:0048545| response to steroid hormone stimulus UGT1A1;OXTR GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;OXTR GO:0014070| response to organic cyclic compound OXTR;UGT1A1 GO:0042755| eating behavior OPRK1;OXTR;OPRD1;OPRM1 GO:0042220| response to cocaine OPRK1;OPRM1;OXTR 8362:[DB01183 DB01143] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways GO:0006955| immune response OPRD1;OPRK1;TLR4;ENPP1 GO:0008152| metabolic process ALPPL2;ALPL;ENPP1;UGT1A1;CES1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;ALPL GO:0006898| receptor-mediated endocytosis ENPP1;ALB GO:0051384| response to glucocorticoid stimulus ALPL;UGT1A1 8363:[DB01183 DB02715] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02715|Compound 18 ESR1 common genes ESR1 common pathways GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 8364:[DB01183 DB00226] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0042493| response to drug UGT1A1;SLC6A2;CREB1;ABCB1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLCO1A2 8365:[DB01183 DB01321] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01321|Josamycin rplD;CYP3A4 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 8366:[DB01183 DB01915] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01915|S-Hydroxycysteine C3;GSTP1;ACAT2;GSTA1;PMP2 common genes common pathways GO:0098869| GSTA1;GSTP1;ALB GO:0002376| immune system process C3;TLR4 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;C3;ESR1;TLR4;CREB1;OPRK1 GO:0032355| response to estradiol stimulus ESR1;GSTP1 GO:0007186| G-protein coupled receptor signaling pathway C3;OPRM1;OPRD1;OPRK1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0009636| response to toxin CES1;GSTP1 GO:0030855| epithelial cell differentiation CES1;GSTA1 GO:0044267| cellular protein metabolic process ALB;C3 GO:0008152| metabolic process ACAT2;CES1;UGT1A1;GSTA1;GSTP1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;OPRK1 GO:0006629| lipid metabolic process C3;ACAT2;CYP3A4 GO:0045087| innate immune response TLR4;C3 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0006695| cholesterol biosynthetic process CES1;ACAT2 GO:0045471| response to ethanol OPRM1;UGT1A1;GSTP1;OPRK1 GO:0006955| immune response C3;OPRD1;TLR4;OPRK1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0006954| inflammatory response C3;TLR4 GO:0043687| post-translational protein modification ALB;C3 8367:[DB01183 DB07593] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07593|1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 8368:[DB01183 DB08361] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways GO:0006468| protein phosphorylation CREB1;SYK GO:0002376| immune system process TLR4;SYK GO:0000187| activation of MAPK activity TLR4;SYK GO:0045087| innate immune response TLR4;SYK GO:0042742| defense response to bacterium TLR4;SYK GO:0016032| viral reproduction CREB1;SYK GO:0006954| inflammatory response SYK;TLR4 8369:[DB01183 DB07159] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07159|Tamatinib SYK common genes common pathways GO:0000187| activation of MAPK activity SYK;TLR4 GO:0002376| immune system process SYK;TLR4 GO:0006468| protein phosphorylation CREB1;SYK GO:0006954| inflammatory response TLR4;SYK GO:0016032| viral reproduction CREB1;SYK GO:0042742| defense response to bacterium TLR4;SYK GO:0045087| innate immune response TLR4;SYK 8370:[DB01183 DB00114] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0043278| response to morphine OPRK1;SRR;OPRM1 GO:0035094| response to nicotine ABAT;CREB1 GO:0008210| estrogen metabolic process UGT1A1;SGPL1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CTH;TLR4 GO:0055114| oxidation-reduction process CYP3A4;PNPO;GLDC;CBS;CYP2C8 GO:0008209| androgen metabolic process SGPL1;ESR1;CYP3A4 GO:0007268| synaptic transmission OPRK1;GAD2;GAD1;OPRD1;OPRM1 GO:0042493| response to drug GAD2;GAD1;ABAT;SRR;ABCB1;CREB1;UGT1A1 GO:0006629| lipid metabolic process SGPL1;SPTLC1;SPTLC3;SPTLC2;CYP3A4 GO:0070266| necroptosis PYGL;TLR4 GO:0008152| metabolic process PDXP;GCAT;FTCD;SRR;ALAS2;BCAT2;SPTLC3;CBS;UGT1A1;PYGL;PYGB;BCAT1;ALAS1;PYGM;SPTLC2;CES1 GO:0048148| behavioral response to cocaine OPRK1;ABAT GO:0043066| negative regulation of apoptotic process ALB;CTH GO:0007626| locomotory behavior OPRM1;OPRK1;ABAT GO:0045471| response to ethanol ABAT;OPRK1;UGT1A1;GOT2;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;SGPL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;TLR4 GO:0007623| circadian rhythm CREB1;DDC GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;SRR GO:0001666| response to hypoxia CREB1;ABAT;ALAS2 GO:1990830| GLDC;CREB1;BCAT2;SHMT1;CTH GO:0042220| response to cocaine OPRK1;ABAT;OPRM1 GO:0009636| response to toxin DDC;CES1 GO:0014070| response to organic cyclic compound UGT1A1;TAT;SRR GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;AGXT2 GO:0007568| aging CREB1;SRR;ABAT GO:0030154| cell differentiation IGSF10;CREB1 GO:0051384| response to glucocorticoid stimulus TAT;UGT1A1;GOT1;AGXT GO:0071363| cellular response to growth factor stimulus OPRD1;DDC;CREB1 8371:[DB01183 DB02931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;AANAT GO:0032868| response to insulin stimulus OPRK1;AANAT GO:0048511| rhythmic process AANAT;CREB1 GO:0007623| circadian rhythm CREB1;AANAT 8372:[DB01183 DB05513] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05513|Atiprimod IL6;TNF common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;OPRM1 GO:0044267| cellular protein metabolic process ALB;IL6 GO:0000187| activation of MAPK activity TLR4;TNF GO:0008285| negative regulation of cell proliferation IL6;OPRM1 GO:0010033| response to organic substance TNF;CREB1;UGT1A1 GO:0010628| positive regulation of gene expression IL6;TNF;TLR4 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1;IL6 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;TNF;OPRD1 GO:0032722| positive regulation of chemokine production IL6;TLR4;TNF GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TLR4;TNF;IL6 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;TNF GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0043687| post-translational protein modification IL6;ALB GO:0042742| defense response to bacterium TNF;TLR4 GO:0051607| defense response to virus OPRK1;IL6 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;TNF GO:0045893| positive regulation of transcription, DNA-dependent ESR1;IL6;CREB1;TNF GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0006953| acute-phase response UGT1A1;IL6 GO:0006954| inflammatory response TLR4;TNF;IL6 GO:0051092| positive regulation of NF-kappaB transcription factor activity IL6;TLR4;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;TNF;ESR1 GO:0006955| immune response OPRD1;TLR4;TNF;IL6;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0097190| apoptotic signaling pathway TNF;TLR4 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0046330| positive regulation of JNK cascade TNF;TLR4 GO:0032729| positive regulation of interferon-gamma production TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:0050829| defense response to Gram-negative bacterium IL6;TLR4 GO:0071222| cellular response to lipopolysaccharide IL6;OPRK1;TNF;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;TNF;CREB1;IL6;ESR1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process IL6;TNF;CREB1 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TNF GO:0043066| negative regulation of apoptotic process IL6;ALB GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 8373:[DB01183 DB11091] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;CREB1 GO:0032355| response to estradiol stimulus ESR1;CAT GO:0007568| aging CREB1;CAT GO:0098869| CAT;GPX1;ALB GO:0009636| response to toxin CES1;GPX1;CAT GO:0032868| response to insulin stimulus OPRK1;CAT GO:0001666| response to hypoxia CREB1;CAT GO:0014823| response to activity CAT;CREB1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;CAT GO:0043066| negative regulation of apoptotic process CAT;GPX1;ALB GO:0008152| metabolic process CES1;ALPPL2;UGT1A1 GO:0009314| response to radiation OPRM1;CAT;OPRK1 GO:0006629| lipid metabolic process GPX1;CYP3A4 GO:0042493| response to drug CAT;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process CAT;GPX1;CYP3A4;CYP2C8 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CAT 8374:[DB01183 DB13153] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B3;SLCO1B1;ALB GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLCO1B3;SLCO1B1 GO:0006811| ion transport SLCO1B1;SLCO1B3;SLCO1A2 GO:0015711| organic anion transport SLCO1A2;SLCO1B1;SLCO1B3 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B1;SLCO1B3;ALB 8375:[DB01183 DB08340] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08340|N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CSNK2A1;CREB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;CSNK2A1;OPRD1 GO:0006468| protein phosphorylation CREB1;CSNK2A1 GO:0048511| rhythmic process CSNK2A1;CREB1 8376:[DB01183 DB11640] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0007268| synaptic transmission OPRD1;OPRM1;KCNA1;OPRK1 GO:0006805| xenobiotic metabolic process CYP2C8;NAT2;NAT1;CYP3A4;CES1 GO:0008152| metabolic process NAT1;NAT2;UGT1A1;CES1 GO:0055085| transmembrane transport KCNA1;ABCB1;SLCO1A2 GO:0006811| ion transport SLCO1A2;KCNA1 8377:[DB01183 DB08270] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08270|N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 8378:[DB01183 DB02860] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02860|Calyculin A PPP1CC common genes common pathways GO:0042752| regulation of circadian rhythm PPP1CC;CREB1 GO:0048511| rhythmic process CREB1;PPP1CC 8379:[DB01183 DB00020] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00020|Sargramostim CSF2RA;IL3RA;CSF2RB;SDC2;PRG2 common genes common pathways GO:0030154| cell differentiation SDC2;CREB1 GO:0002376| immune system process TLR4;PRG2 GO:0007165| signal transduction CSF2RB;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0044267| cellular protein metabolic process CSF2RA;ALB;CSF2RB;SDC2 GO:0032496| response to lipopolysaccharide OPRM1;CSF2RB;TLR4;UGT1A1 GO:0043687| post-translational protein modification SDC2;ALB GO:0042742| defense response to bacterium TLR4;PRG2 GO:0006955| immune response OPRK1;TLR4;PRG2;OPRD1 8380:[DB01183 DB03193] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0042060| wound healing OPRM1;PPARA GO:0006351| transcription, DNA-dependent CREB1;PPARA;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARA GO:0043066| negative regulation of apoptotic process ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;ESR1;CREB1;TLR4 GO:0002576| platelet degranulation ALB GO:0006629| lipid metabolic process PLA2G2D;PPARA;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARA;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PPARA GO:0042493| response to drug UGT1A1;CREB1;ABCB1;FABP3 GO:0043687| post-translational protein modification ALB GO:1901215| PPARA;CREB1 GO:0006954| inflammatory response PLA2G2D;TLR4 GO:0042752| regulation of circadian rhythm PPARA;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;ESR1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0032868| response to insulin stimulus PPARA;FABP3;OPRK1 GO:0001666| response to hypoxia PPARA;CREB1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0008285| negative regulation of cell proliferation OPRM1;FABP3 GO:0048511| rhythmic process CREB1;PPARA 8381:[DB01183 DB11569] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11569|Ixekizumab IL17A common genes common pathways GO:1900017| IL17A;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;IL17A GO:0045672| positive regulation of osteoclast differentiation CREB1;IL17A GO:0006955| immune response OPRD1;OPRK1;IL17A;TLR4 GO:0006954| inflammatory response IL17A;TLR4 8382:[DB01183 DB06345] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06345|AR-9281 EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP3A4;UGT1A1;CYP2C8 GO:0009636| response to toxin CES1;EPHX2 GO:0010628| positive regulation of gene expression EPHX2;TLR4 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0006805| xenobiotic metabolic process CYP2C8;EPHX2;CYP3A4;CES1 GO:0008152| metabolic process UGT1A1;CES1;EPHX2 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0006954| inflammatory response EPHX2;TLR4 8383:[DB01183 DB01130] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;NR3C1 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;OPRM1;OPRD1;NR3C1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 8384:[DB01183 DB06151] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;GRIN2D;OPRM1;GRIN2A GO:0006811| ion transport GRIN3A;SLCO1A2;GRIN2D;GRIN1;SLCO1B1;GRIN2B;GRIN2A GO:0009636| response to toxin CHUK;CES1;SLC7A11 GO:0055085| transmembrane transport SLCO1B1;SLCO1A2;SLC22A6;ABCB1 GO:0008344| adult locomotory behavior GRIN1;GRIN2D;OPRD1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1A2 GO:1903428| GRIN1;TLR4 GO:1904646| TLR4;GRIN2A;GRIN1 GO:0010033| response to organic substance CREB1;UGT1A1;CHUK GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKB;CHUK;TLR4 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1A2;ALB;SLC22A6 GO:0006468| protein phosphorylation CREB1;CHUK;IKBKB GO:0007613| memory CREB1;GRIN2A;GRIN1 GO:0007568| aging CREB1;GSS GO:0006810| transport ABCB1;GRIN2A;GRIN2B GO:0070588| calcium ion transmembrane transport OPRM1;GRIN3A GO:1900273| CREB1;GRIN2A GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKB;CHUK;TLR4 GO:0015711| organic anion transport SLC22A6;SLCO1A2;SLCO1B1 GO:0007268| synaptic transmission OPRD1;OPRM1;GRIN2B;GRIN2A;OPRK1 GO:0042493| response to drug GRIN2A;CHUK;ABCB1;CREB1;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;CHUK;IKBKB;ESR1 GO:0043491| protein kinase B signaling cascade CREB1;CHUK GO:0051092| positive regulation of NF-kappaB transcription factor activity CHUK;IKBKB;TLR4 GO:0006954| inflammatory response CHUK;IKBKB;TLR4 GO:0007252| I-kappaB phosphorylation TLR4;IKBKB;CHUK GO:0006955| immune response TLR4;OPRK1;OPRD1;CHUK GO:0043278| response to morphine OPRM1;GRIN1;OPRK1 GO:0008542| visual learning GRIN1;GRIN2A;CREB1 GO:0035094| response to nicotine SLC7A11;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;CHUK;UGT1A1;TLR4 GO:0002756| MyD88-independent toll-like receptor signaling pathway TLR4;CHUK;IKBKB GO:0045471| response to ethanol OPRK1;GRIN3A;UGT1A1;GRIN2A;GRIN2B;OPRM1;GRIN1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CHUK;IKBKB;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN3A;GRIN2B;GRIN2D;GRIN1;OPRM1;GRIN2A GO:0019233| sensory perception of pain OPRK1;GRIN2A;GRIN1;OPRM1;OPRD1 GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;IKBKB;CHUK;CREB1;TLR4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;ACY1;CYP2C8 GO:0008152| metabolic process UGT1A1;CES1;ACY1 GO:0043066| negative regulation of apoptotic process IKBKB;ALB GO:0045087| innate immune response IKBKB;CHUK;TLR4 8385:[DB01183 DB07125] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07125|4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid DAPK3 common genes common pathways GO:0006468| protein phosphorylation DAPK3;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;DAPK3;CREB1 GO:0097190| apoptotic signaling pathway DAPK3;TLR4 GO:0006351| transcription, DNA-dependent CREB1;DAPK3;ESR1 GO:0042981| regulation of apoptotic process CREB1;DAPK3;ESR1 GO:0043065| positive regulation of apoptotic process DAPK3;CREB1 8386:[DB01183 DB03704] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ADH5;CYP3A4 GO:0032496| response to lipopolysaccharide ADH5;UGT1A1;TLR4;OPRM1 8387:[DB01183 DB06634] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06634|Casopitant CYP3A4;TACR1 common genes CYP3A4 common pathways GO:0007204| elevation of cytosolic calcium ion concentration TACR1;OPRM1;ESR1 GO:0032355| response to estradiol stimulus TACR1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;TACR1;OPRM1;OPRK1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;TACR1;OPRD1;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0042755| eating behavior OPRM1;TACR1;OPRD1;OPRK1 GO:0002933| CYP2C8;CYP3A4 GO:0014070| response to organic cyclic compound TACR1;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0045471| response to ethanol OPRK1;UGT1A1;TACR1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;TACR1;OPRM1 GO:0042737| drug catabolic process CYP3A4 GO:0019233| sensory perception of pain OPRM1;TACR1;OPRD1;OPRK1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0050671| positive regulation of lymphocyte proliferation TACR1;TLR4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0007268| synaptic transmission OPRM1;TACR1;OPRD1;OPRK1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0046887| positive regulation of hormone secretion TACR1;CREB1 GO:0043278| response to morphine OPRK1;OPRM1;TACR1 GO:0035094| response to nicotine TACR1;CREB1 GO:0006954| inflammatory response TLR4;TACR1 8388:[DB01183 DB05024] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;VDR GO:0010628| positive regulation of gene expression TLR4;VDR GO:0042359| vitamin D metabolic process CYP3A4;CYP24A1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;VDR GO:0055114| oxidation-reduction process CYP2C8;CYP24A1;CYP3A4 GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;VDR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;VDR GO:0007595| lactation VDR;CREB1 GO:0043401| steroid hormone mediated signaling pathway VDR;ESR1 GO:0006351| transcription, DNA-dependent CREB1;VDR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;VDR;TLR4;CREB1 8389:[DB01183 DB08869] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08869|Tesamorelin GHRHR common genes common pathways GO:0043627| response to estrogen stimulus ESR1;GHRHR;OPRK1 GO:0030879| mammary gland development GHRHR;CREB1 GO:0032868| response to insulin stimulus OPRK1;GHRHR GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;GHRHR;CREB1;OPRK1 GO:0051384| response to glucocorticoid stimulus GHRHR;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway GHRHR;OPRK1;OPRM1;OPRD1 GO:0040018| positive regulation of multicellular organism growth GHRHR;CREB1 GO:0007595| lactation GHRHR;CREB1 GO:0046887| positive regulation of hormone secretion GHRHR;CREB1 8390:[DB01183 DB08676] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08676|(20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CREB1 8391:[DB01183 DB03509] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03509|2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide PARP1 common genes common pathways GO:0071294| cellular response to zinc ion PARP1;CREB1 GO:0006351| transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;ESR1;TLR4;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PARP1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP1;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;PARP1 GO:1904646| TLR4;PARP1 8392:[DB01183 DB07465] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 8393:[DB01183 DB03507] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways GO:0050729| positive regulation of inflammatory response TLR4;TNFRSF1A GO:0007249| I-kappaB kinase/NF-kappaB cascade TNFRSF1A;TLR4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;TNFRSF1A GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;TNFRSF1A;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNFRSF1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;TNFRSF1A;ESR1 GO:0042981| regulation of apoptotic process CREB1;TNFRSF1A;ESR1 GO:0071260| cellular response to mechanical stimulus TNFRSF1A;TLR4 GO:0042742| defense response to bacterium TLR4;TNFRSF1A GO:0006954| inflammatory response TLR4;TNFRSF1A GO:0006955| immune response TLR4;TNFRSF1A;OPRK1;OPRD1 GO:0016032| viral reproduction CREB1;TNFRSF1A 8394:[DB01183 DB07662] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07662|N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE SRC;EGFR common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;ABCB1;SRC GO:0045893| positive regulation of transcription, DNA-dependent ESR1;SRC;CREB1;EGFR GO:0016032| viral reproduction CREB1;SRC GO:0001889| liver development EGFR;UGT1A1 GO:0042060| wound healing OPRM1;EGFR GO:0007623| circadian rhythm EGFR;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;EGFR GO:0045087| innate immune response TLR4;SRC GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0043065| positive regulation of apoptotic process SRC;CREB1 GO:0030520| intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;CREB1;TLR4;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;SRC GO:0071398| cellular response to fatty acid SRC;CREB1 GO:0043066| negative regulation of apoptotic process EGFR;ALB;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC;CREB1 GO:0060065| uterus development ESR1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade EGFR;TLR4;SRC;OPRM1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0007411| axon guidance CREB1;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0010628| positive regulation of gene expression TLR4;SRC GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0006468| protein phosphorylation CREB1;EGFR;SRC GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0036120| CREB1;SRC GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0071363| cellular response to growth factor stimulus OPRD1;EGFR;CREB1 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0007165| signal transduction TLR4;CREB1;OPRK1;EGFR;ESR1;OPRD1;OPRM1;SRC GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0002376| immune system process SRC;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;EGFR;OPRM1;ESR1 8395:[DB01183 DB06422] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06422|Ticalopride HTR4;HTR3A common genes common pathways GO:0007165| signal transduction OPRD1;HTR4;OPRM1;ESR1;TLR4;CREB1;HTR3A;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;HTR4;OPRK1 GO:0071363| cellular response to growth factor stimulus OPRD1;HTR3A;CREB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;HTR4;OPRD1 GO:0042220| response to cocaine OPRM1;HTR3A;OPRK1 GO:0006811| ion transport HTR3A;SLCO1A2 GO:0045471| response to ethanol OPRK1;HTR3A;UGT1A1;OPRM1 GO:0007268| synaptic transmission OPRK1;HTR3A;OPRD1;HTR4;OPRM1 8396:[DB01183 DB05869] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;TNF;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;TNF;CREB1 GO:0042742| defense response to bacterium TLR4;TNF GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0002218| activation of innate immune response HMGB1;TLR4 GO:0006955| immune response OPRD1;OPRK1;TLR4;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TLR4 GO:0006954| inflammatory response HMGB1;TNF;TLR4 GO:0032729| positive regulation of interferon-gamma production TNF;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter HMGB1;ESR1 GO:0046330| positive regulation of JNK cascade TLR4;TNF;HMGB1 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0043065| positive regulation of apoptotic process HMGB1;TNF;CREB1 GO:0050727| regulation of inflammatory response ESR1;TLR4;TNF GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;TNF;HMGB1 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;OPRK1 GO:0045087| innate immune response HMGB1;TLR4 GO:0032733| positive regulation of interleukin-10 production HMGB1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;HMGB1;ESR1 GO:0000187| activation of MAPK activity TNF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGB1;TNF;TLR4;OPRM1 GO:0010628| positive regulation of gene expression TNF;TLR4 GO:0010033| response to organic substance UGT1A1;CREB1;TNF GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0032735| positive regulation of interleukin-12 production HMGB1;TLR4 GO:0002224| toll-like receptor signaling pathway HMGB1;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HMGB1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TNF;TLR4 GO:0002376| immune system process HMGB1;TLR4 GO:0032689| negative regulation of interferon-gamma production HMGB1;TLR4 GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0032722| positive regulation of chemokine production TNF;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;TNF 8397:[DB01183 DB01629] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;SOD1 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0002576| platelet degranulation ALB;SOD1 GO:0043065| positive regulation of apoptotic process SOD1;CREB1 GO:0043066| negative regulation of apoptotic process ALB;SOD1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP2C8 GO:0042493| response to drug SOD1;CREB1;UGT1A1;ABCB1 GO:0007568| aging SOD1;CREB1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0000187| activation of MAPK activity SOD1;TLR4 GO:0001895| retina homeostasis ALB;SOD1 GO:0010033| response to organic substance CREB1;UGT1A1;SOD1 8398:[DB01183 DB12478] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0001666| response to hypoxia CREB1;DRD2 GO:0042220| response to cocaine OPRM1;OPRK1;DRD2;DRD3 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 GO:0007165| signal transduction OPRK1;DRD2;CREB1;DRD3;TLR4;ESR1;OPRM1;OPRD1 GO:1900273| DRD2;CREB1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;DRD3;DRD2;OPRK1 GO:0035094| response to nicotine CREB1;DRD2 GO:0043278| response to morphine OPRM1;DRD3;OPRK1;DRD2 GO:0008542| visual learning DRD3;CREB1;DRD2 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0042493| response to drug ABCB1;DRD2;DRD3;CREB1;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 GO:0048148| behavioral response to cocaine DRD3;DRD2;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;DRD3;CREB1;DRD2;ESR1 GO:0007626| locomotory behavior DRD2;OPRK1;DRD3;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol DRD3;UGT1A1;OPRK1;DRD2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 8399:[DB01183 DB02936] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02936|4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 GO:0050729| positive regulation of inflammatory response TLR4;PLA2G2A GO:0070374| positive regulation of ERK1 and ERK2 cascade PLA2G2A;TLR4;OPRM1 8400:[DB01183 DB02335] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02335|2-Aminothiazoline NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 8401:[DB01183 DB00824] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0008285| negative regulation of cell proliferation ADORA1;ADORA2A;ADORA3;OPRM1 GO:0001666| response to hypoxia ADORA1;CREB1 GO:0044267| cellular protein metabolic process ADORA2A;ADORA2B;ALB GO:0000187| activation of MAPK activity TLR4;ADORA2B GO:0051881| regulation of mitochondrial membrane potential OPRD1;ADORA2A GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADORA1;OPRK1 GO:0042755| eating behavior OPRM1;OPRD1;OPRK1;ADORA2A GO:0032722| positive regulation of chemokine production ADORA2B;TLR4 GO:0007165| signal transduction ADORA2A;TLR4;ADORA3;ADORA1;CREB1;ADORA2B;OPRK1;PDE4B;PDE4A;OPRD1;OPRM1;ESR1 GO:0032755| positive regulation of interleukin-6 production TLR4;ADORA2B GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADORA1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway PDE4B;OPRK1;ADORA2B;ADORA1;ADORA3;ADORA2A;OPRM1;PDE4A;OPRD1 GO:0007600| sensory perception OPRM1;OPRK1;ADORA2A GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0006954| inflammatory response ADORA3;TLR4;ADORA2A;ADORA1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ADORA2A;ESR1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;ADORA2A GO:0043066| negative regulation of apoptotic process ADORA1;ALB GO:0071222| cellular response to lipopolysaccharide TLR4;PDE4B;OPRK1 GO:0007626| locomotory behavior OPRK1;ADORA2A;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA1;ADORA2A;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;ADORA1 GO:0032729| positive regulation of interferon-gamma production PDE4B;TLR4 8402:[DB01183 DB11834] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11834|Guselkumab IL23A common genes common pathways GO:0050729| positive regulation of inflammatory response TLR4;IL23A GO:0032735| positive regulation of interleukin-12 production IL23A;TLR4 GO:0002376| immune system process IL23A;TLR4 GO:0051607| defense response to virus IL23A;OPRK1 GO:0032760| positive regulation of tumor necrosis factor production IL23A;TLR4 GO:0006955| immune response OPRD1;IL23A;TLR4;OPRK1 GO:0006954| inflammatory response IL23A;TLR4 GO:0032729| positive regulation of interferon-gamma production TLR4;IL23A GO:0032733| positive regulation of interleukin-10 production TLR4;IL23A GO:0045087| innate immune response IL23A;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;IL23A GO:0045672| positive regulation of osteoclast differentiation IL23A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;IL23A;ESR1 GO:0050829| defense response to Gram-negative bacterium IL23A;TLR4 8403:[DB01183 DB02546] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC1;HDAC2;HDAC8;HDAC3;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;HDAC2 GO:0043066| negative regulation of apoptotic process ALB;HDAC1;HDAC2;HDAC3 GO:0070848| response to growth factor stimulus HDAC6;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;TLR4;CREB1;HDAC3;HDAC2;ESR1 GO:0006351| transcription, DNA-dependent HDAC6;ESR1;HDAC3;HDAC2;HDAC8;HDAC1;CREB1 GO:0007623| circadian rhythm CREB1;HDAC3 GO:0032496| response to lipopolysaccharide OPRM1;HDAC2;UGT1A1;TLR4;HDAC1 GO:0035094| response to nicotine HDAC2;CREB1 GO:0032760| positive regulation of tumor necrosis factor production HDAC2;HDAC1;TLR4 GO:0016032| viral reproduction CREB1;HDAC1 GO:0048149| behavioral response to ethanol OPRM1;HDAC2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;HDAC2;HDAC1;CREB1 GO:0042493| response to drug HDAC2;ABCB1;CREB1;HDAC1;UGT1A1 GO:0010629| negative regulation of gene expression HDAC8;ESR1;OPRD1;HDAC1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HDAC1;HDAC8;HDAC2;HDAC3;ESR1;HDAC6 GO:0006338| chromatin remodeling HDAC1;HDAC2;ESR1 GO:0032732| positive regulation of interleukin-1 production TLR4;HDAC1;HDAC2 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC2 GO:0008285| negative regulation of cell proliferation OPRM1;HDAC1 GO:0010033| response to organic substance HDAC6;CREB1;UGT1A1 GO:0048511| rhythmic process HDAC1;CREB1;HDAC2 GO:0042220| response to cocaine HDAC2;OPRM1;OPRK1 GO:0009636| response to toxin CES1;HDAC6 8404:[DB01183 DB00848] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA3;OPRM1 GO:0007626| locomotory behavior CHRNA3;OPRK1;OPRM1 GO:0008152| metabolic process UGT1A1;ALPPL2;CES1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CHRNA3;CREB1;TLR4 GO:0006811| ion transport CHRNA3;SLCO1A2 8405:[DB01183 DB04947] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04947|Altropane SLC6A3 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC6A3 GO:0042220| response to cocaine OPRM1;OPRK1;SLC6A3 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0040018| positive regulation of multicellular organism growth CREB1;SLC6A3 GO:0007568| aging CREB1;SLC6A3 GO:0007595| lactation SLC6A3;CREB1 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0042493| response to drug ABCB1;SLC6A3;UGT1A1;CREB1 GO:0007626| locomotory behavior SLC6A3;OPRK1;OPRM1 GO:0045471| response to ethanol UGT1A1;SLC6A3;OPRK1;OPRM1 8406:[DB01183 DB01860] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 8407:[DB01183 DB02917] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;ESR1 GO:0006351| transcription, DNA-dependent ESR1;HDAC8;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;HDAC8 GO:0010629| negative regulation of gene expression CREB1;HDAC8;OPRD1;ESR1 8408:[DB01183 DB11124] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;ABCB1;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;ADRA1B;ADRA1D;OPRK1;ADRA1A GO:1904646| TLR4;ADRB2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;ADRB3 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0042755| eating behavior OPRK1;ADRB3;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADRA2C;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007165| signal transduction CREB1;TLR4;ADRA1D;ADRA2A;ADRB3;OPRK1;ADRA1A;ADRB1;ESR1;ADRA2C;ADRA2B;ADRB2;OPRM1;OPRD1;ADRA1B GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;ADRA2C;ADRA2B;ADRB2;OPRM1;OPRD1;ADRA2A;OPRK1;ADRB3;ADRB1;ADRA1A;ADRA1D GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;OPRM1;ESR1;ADRA1B GO:0007568| aging ADRA1A;ADRB3;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 8409:[DB01183 DB02226] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 8410:[DB01183 DB09018] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09018|Bromopride DRD2 common genes common pathways GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug DRD2;ABCB1;CREB1;UGT1A1 GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning DRD2;CREB1 GO:0043278| response to morphine OPRM1;DRD2;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0048148| behavioral response to cocaine DRD2;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;DRD2 GO:0007626| locomotory behavior OPRM1;OPRK1;DRD2 GO:0042220| response to cocaine OPRM1;OPRK1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0009636| response to toxin CES1;DRD2 GO:0007409| axonogenesis CREB1;DRD2 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0001666| response to hypoxia DRD2;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;DRD2 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;DRD2;TLR4;CREB1 GO:1900273| DRD2;CREB1 8411:[DB01183 DB01096] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01096|Oxamniquine CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CES1;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 8412:[DB01183 DB06587] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06587|Mitemcinal MLNR;CYP3A4 common genes CYP3A4 common pathways GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway MLNR;OPRK1;OPRD1;OPRM1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction OPRK1;MLNR;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP3A4 GO:0007586| digestion UGT1A1;MLNR GO:0006706| steroid catabolic process CYP3A4 8413:[DB01183 DB05990] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0015721| bile acid and bile salt transport NR1H4;SLCO1A2;ALB GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0034142| toll-like receptor 4 signaling pathway NR1H4;TLR4 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0031100| organ regeneration UGT1A1;BAAT GO:0002376| immune system process TLR4;NR1H4 GO:0032720| negative regulation of tumor necrosis factor production TLR4;NR1H4 GO:0032689| negative regulation of interferon-gamma production TLR4;NR1H4 GO:0032715| negative regulation of interleukin-6 production TLR4;NR1H4 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;OPRD1;NR1H4;OPRM1 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0006954| inflammatory response TLR4;NR1H4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1H4 GO:0006355| regulation of transcription, DNA-dependent NR1H4;ESR1;CREB1 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042742| defense response to bacterium TLR4;NR1H4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;NR1H4;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;NR1H4 GO:0043066| negative regulation of apoptotic process ALB;NR1H4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8 GO:0071398| cellular response to fatty acid NR1H4;CREB1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0045087| innate immune response NR1H4;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;ESR1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process BAAT;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR1H4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade NR1H4;ESR1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;NR1H4;ESR1 GO:0001889| liver development UGT1A1;BAAT GO:0043401| steroid hormone mediated signaling pathway NR1H4;ESR1 8414:[DB01183 DB06061] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06061|AZD-8330 MAP3K1 common genes common pathways GO:0006468| protein phosphorylation MAP3K1;CREB1 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR4;MAP3K1 GO:0042981| regulation of apoptotic process CREB1;ESR1;MAP3K1 GO:0071260| cellular response to mechanical stimulus MAP3K1;TLR4 8415:[DB01183 DB05797] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05797|TNX-901 FCER1A common genes common pathways 8416:[DB01183 DB04700] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways GO:0098869| GSTK1;ALB GO:0030855| epithelial cell differentiation CES1;GSTK1 GO:0055114| oxidation-reduction process GSTK1;CYP3A4;CYP2C8 8417:[DB01183 DB04593] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways GO:0007623| circadian rhythm CREB1;F7 GO:0032355| response to estradiol stimulus ESR1;F7 GO:0031100| organ regeneration UGT1A1;F7 GO:0014070| response to organic cyclic compound UGT1A1;F7 GO:0043627| response to estrogen stimulus ESR1;OPRK1;F7 GO:0001666| response to hypoxia CREB1;F7 8418:[DB01183 DB03082] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03082|6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide PLAU common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;PLAU;TLR4;CREB1 GO:0001666| response to hypoxia CREB1;PLAU 8419:[DB01183 DB02209] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PNPO 8420:[DB01183 DB05088] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05088|Tiomolibdate ion APP common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1 GO:1900273| CREB1;APP GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TLR4;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;APP GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;APP GO:0007613| memory APP;CREB1 GO:0006468| protein phosphorylation APP;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;APP;OPRK1 GO:0008285| negative regulation of cell proliferation APP;OPRM1 GO:1903223| TLR4;APP GO:1904646| APP;TLR4 GO:0010628| positive regulation of gene expression TLR4;APP GO:0044267| cellular protein metabolic process ALB;APP GO:0008344| adult locomotory behavior OPRD1;APP GO:0000187| activation of MAPK activity TLR4;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;TLR4;OPRM1 GO:0007409| axonogenesis CREB1;APP GO:0045087| innate immune response APP;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;ESR1 GO:1990090| CREB1;APP GO:0042346| positive regulation of NF-kappaB import into nucleus APP;TLR4 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0007626| locomotory behavior OPRK1;APP;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;APP GO:0002576| platelet degranulation APP;ALB GO:0043065| positive regulation of apoptotic process APP;CREB1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0046330| positive regulation of JNK cascade TLR4;APP GO:0008542| visual learning APP;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TLR4 GO:0043687| post-translational protein modification ALB;APP GO:1901215| CREB1;APP GO:0010629| negative regulation of gene expression CREB1;APP;ESR1;OPRD1 GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;APP 8421:[DB01183 DB04351] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04351|Aconitate Ion ACO2 common genes common pathways GO:0008152| metabolic process ACO2;UGT1A1;CES1 GO:0001889| liver development UGT1A1;ACO2 8422:[DB01183 DB08590] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;IRAK4;CREB1;TLR4;OPRK1 GO:0002376| immune system process TLR4;IRAK4 GO:0002224| toll-like receptor signaling pathway IRAK4;TLR4 GO:0006468| protein phosphorylation IRAK4;CREB1 GO:0045087| innate immune response TLR4;IRAK4 GO:0002755| MyD88-dependent toll-like receptor signaling pathway IRAK4;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IRAK4;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity IRAK4;TLR4 8423:[DB01183 DB05749] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05749|MPI-674 CYP19A1 common genes common pathways GO:0030879| mammary gland development CYP19A1;CREB1 GO:0060065| uterus development ESR1;CYP19A1 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP19A1 8424:[DB01183 DB09363] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC18A2;SLCO1A2;SLC6A2;ABCB1 GO:0009636| response to toxin CES1;SLC18A2;MAOB GO:0007626| locomotory behavior OPRM1;SLC18A2;OPRK1 GO:0045471| response to ethanol OPRK1;UGT1A1;MAOB;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;MAOB;UGT1A1 GO:0055114| oxidation-reduction process MAOA;CYP3A4;MAOB;CYP2C8 GO:0042493| response to drug ABCB1;CREB1;SLC6A2;MAOB;UGT1A1 GO:0007268| synaptic transmission SLC6A2;OPRK1;OPRM1;OPRD1;SLC18A2 8425:[DB01183 DB04888] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning CREB1;DRD2 GO:0043278| response to morphine OPRM1;OPRK1;DRD2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;DRD2 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0007626| locomotory behavior OPRK1;DRD2;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;CREB1;TLR4;ESR1 GO:0048148| behavioral response to cocaine DRD2;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;DRD2;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0001666| response to hypoxia DRD2;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;DRD2;TLR4 GO:0042220| response to cocaine DRD2;OPRK1;OPRM1 GO:0007409| axonogenesis DRD2;CREB1 GO:0009636| response to toxin DRD2;CES1 GO:0007610| behavior OPRK1;HTR1A GO:0007165| signal transduction HTR1A;ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;DRD2 GO:1900273| CREB1;DRD2 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;OPRD1;OPRM1;OPRK1;DRD2 8426:[DB01183 DB01858] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01858|[1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway CTSK;TLR4 8427:[DB01183 DB14010] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4;CES1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2A;ESR1;OPRD1;OPRM1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0016032| viral reproduction CREB1;HTR2A GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0007268| synaptic transmission HTR2A;OPRD1;OPRM1;OPRK1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;HTR2A GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0007165| signal transduction TLR4;CREB1;OPRK1;HTR2A;HTR1A;ESR1;OPRD1;OPRM1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007613| memory HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1 GO:0007568| aging CREB1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;HTR1A;HTR2A GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;TLR4 8428:[DB01183 DB00944] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00944|Demecarium ACHE;BCHE common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;BCHE;ABCB1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation OPRM1;BCHE 8429:[DB01183 DB04345] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways GO:0042167| heme catabolic process UGT1A1;BLVRB GO:0055114| oxidation-reduction process CYP2C8;BLVRB;CYP3A4 8430:[DB01183 DB04836] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0042493| response to drug SLC6A4;ABCB1;CREB1;SLC6A2;UGT1A1 GO:0007268| synaptic transmission OPRM1;OPRD1;SLC6A2;OPRK1 GO:0007613| memory SLC6A4;CREB1 GO:0006810| transport SLC6A2;ABCB1 GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLCO1A2;SLC6A4 GO:0009636| response to toxin CES1;SLC6A4 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0001666| response to hypoxia SLC6A4;CREB1 8431:[DB01183 DB13192] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways GO:0044267| cellular protein metabolic process PROC;ALB GO:0043687| post-translational protein modification ALB;PROC GO:0043066| negative regulation of apoptotic process ALB;PROC GO:0001889| liver development UGT1A1;PROC 8432:[DB01183 DB00211] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0006811| ion transport SLC15A1;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ADRA1A;TLR4 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO1A2 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRA1B;ADRA1D;ADRA1A;OPRK1 GO:0006810| transport SLC15A1;ABCB1 GO:0007568| aging ADRA1A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1D;ADRA1B;ESR1;OPRM1 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007165| signal transduction ADRA1A;OPRK1;ADRA1D;CREB1;TLR4;ADRA1B;OPRM1;OPRD1;ESR1 GO:0042493| response to drug ADRA1A;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ADRA1A;ADRA1D;ADRA1B;ESR1;OPRM1;OPRD1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0007586| digestion SLC15A1;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 8433:[DB01183 DB01564] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01564|Calusterone AR common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;CREB1;TLR4 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;AR GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression TLR4;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0016579| protein deubiquitination AR;ESR1 8434:[DB01183 DB03058] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways GO:0002376| immune system process CFD;TLR4 GO:0002576| platelet degranulation ALB;CFD GO:0045087| innate immune response CFD;TLR4 8435:[DB01183 DB05005] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05005|CCX282 CCR9 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;CCR9 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CCR9;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;CCR9 GO:0006955| immune response TLR4;OPRK1;OPRD1;CCR9 8436:[DB01183 DB08008] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0042594| response to starvation UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0007595| lactation CREB1;DHODH GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHODH GO:0042493| response to drug CREB1;UGT1A1;ABCB1;DHODH GO:0014070| response to organic cyclic compound DHODH;UGT1A1 8437:[DB01183 DB08063] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08063|1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE RXRA;NR1H3 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;RXRA;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR1H3;TLR4;RXRA;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;NR1H3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR1H3;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;ESR1 GO:0006351| transcription, DNA-dependent NR1H3;CREB1;RXRA;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR1H3;RXRA GO:0016032| viral reproduction CREB1;RXRA GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1H3;RXRA GO:0042752| regulation of circadian rhythm NR1H3;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CREB1;NR1H3;ESR1 GO:0006355| regulation of transcription, DNA-dependent RXRA;CREB1;NR1H3;ESR1 8438:[DB01183 DB01754] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01754|3,4-Dihydroxy-1-Methylquinolin-2(1h)-One PIM1 common genes common pathways GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity PIM1;ESR1 GO:0006468| protein phosphorylation CREB1;PIM1 GO:0043066| negative regulation of apoptotic process ALB;PIM1 8439:[DB01183 DB03686] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;OPRK1 GO:0008152| metabolic process GSTP1;UGT1A1;CES1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin GSTP1;CES1 GO:0032355| response to estradiol stimulus ESR1;GSTP1 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0098869| ALB;GSTP1 8440:[DB01183 DB03309] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;EN2 GO:0006629| lipid metabolic process SULT2B1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;EN2 GO:0008285| negative regulation of cell proliferation OPRM1;SULT2B1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;SULT2B1 8441:[DB01183 DB08118] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08118|2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways GO:0008152| metabolic process CES1;GCK;UGT1A1 8442:[DB01183 DB04003] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways GO:0042493| response to drug LCK;ABCB1;UGT1A1;CREB1 GO:0016032| viral reproduction CREB1;LCK GO:0045087| innate immune response TLR4;LCK GO:0006468| protein phosphorylation CREB1;LCK 8443:[DB01183 DB04767] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways GO:0014070| response to organic cyclic compound F7;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;F7;OPRK1 GO:0001666| response to hypoxia F7;CREB1 GO:0032355| response to estradiol stimulus ESR1;F7 GO:0031100| organ regeneration UGT1A1;F7 GO:0007623| circadian rhythm CREB1;F7 8444:[DB01183 DB07195] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07195|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes ESR1 common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NCOA2;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;NCOA2 GO:0008584| male gonad development ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0032355| response to estradiol stimulus ESR1 8445:[DB01183 DB08430] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08430|PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE LCTL common genes common pathways 8446:[DB01183 DB03429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03429|Cardiolipin SLC25A4 common genes common pathways GO:0006810| transport SLC25A4;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC25A4;SLCO1A2 GO:0016032| viral reproduction CREB1;SLC25A4 8447:[DB01183 DB04417] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04417|P-Nitrophenol SULT1A1;AMY2B common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;SULT1A1 GO:0008210| estrogen metabolic process UGT1A1;SULT1A1 GO:0006805| xenobiotic metabolic process SULT1A1;CYP2C8;CES1;CYP3A4 GO:0008152| metabolic process CES1;UGT1A1;AMY2B GO:0006629| lipid metabolic process SULT1A1;CYP3A4 GO:0007586| digestion AMY2B;UGT1A1 8448:[DB01183 DB08588] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8449:[DB01183 DB08504] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8450:[DB01183 DB03696] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03696|Lanosterol LSS common genes common pathways GO:0006629| lipid metabolic process LSS;CYP3A4 GO:0006695| cholesterol biosynthetic process LSS;CES1 8451:[DB01183 DB06013] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06013|Aldoxorubicin TOP2A common genes common pathways GO:0048511| rhythmic process CREB1;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TOP2A;TLR4;ESR1 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 8452:[DB01183 DB05968] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05968|PR-104 TNF common genes common pathways GO:0000187| activation of MAPK activity TLR4;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TNF;TLR4 GO:0010033| response to organic substance TNF;CREB1;UGT1A1 GO:0010628| positive regulation of gene expression TNF;TLR4 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;TNF GO:0032755| positive regulation of interleukin-6 production TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;TNF GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0042742| defense response to bacterium TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;TNF;ESR1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0010629| negative regulation of gene expression OPRD1;ESR1;TNF;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;ESR1 GO:0006955| immune response OPRD1;OPRK1;TLR4;TNF GO:0006954| inflammatory response TNF;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TNF GO:0071222| cellular response to lipopolysaccharide TLR4;TNF;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;TNF;ESR1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process TNF;CREB1 8453:[DB01183 DB14004] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0032760| positive regulation of tumor necrosis factor production TLR4;IL12B;IL23A GO:0032609| interferon-gamma production IL12B;TLR4 GO:0006954| inflammatory response TLR4;IL23A GO:0006955| immune response OPRK1;TLR4;IL23A;OPRD1 GO:0055114| oxidation-reduction process CYP3A4;CYP4A11;CYP2C8 GO:0051607| defense response to virus OPRK1;IL12B;IL23A GO:0045087| innate immune response TLR4;IL23A GO:0032733| positive regulation of interleukin-10 production IL12B;TLR4;IL23A GO:0042088| T-helper 1 type immune response IL12B;TLR4 GO:0050829| defense response to Gram-negative bacterium IL23A;TLR4;IL12B GO:0071222| cellular response to lipopolysaccharide IL12B;OPRK1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;IL23A;ESR1 GO:0045672| positive regulation of osteoclast differentiation IL23A;IL12B;CREB1 GO:0019373| epoxygenase P450 pathway CYP4A11;CYP2C8 GO:0042346| positive regulation of NF-kappaB import into nucleus IL12B;TLR4;IL23A GO:0019233| sensory perception of pain IL12B;OPRK1;OPRD1;OPRM1 GO:0032729| positive regulation of interferon-gamma production TLR4;IL12B;IL23A GO:0050671| positive regulation of lymphocyte proliferation IL12B;TLR4 GO:0010033| response to organic substance IL12B;CREB1;UGT1A1 GO:0097267| CYP4A11;CYP2C8 GO:0002376| immune system process IL23A;TLR4 GO:0032700| negative regulation of interleukin-17 production IL12B;TLR4 GO:0032735| positive regulation of interleukin-12 production TLR4;IL12B;IL23A GO:0050729| positive regulation of inflammatory response IL23A;IL12B;TLR4 8454:[DB01183 DB02401] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02401|4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid LDHB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;LDHB;CYP2C8 8455:[DB01183 DB03167] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03167|Pentabromophenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process TTR;ALB 8456:[DB01183 DB05786] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05786|Irofulven FUBP1 common genes common pathways GO:0010628| positive regulation of gene expression TLR4;FUBP1 GO:0006366| transcription from RNA polymerase II promoter FUBP1;CREB1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;FUBP1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;FUBP1 8457:[DB01183 DB00407] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways GO:0007595| lactation SERPINC1;CREB1 GO:0043687| post-translational protein modification SERPIND1;SERPINC1;ALB GO:0007584| response to nutrient UGT1A1;SERPINC1 GO:0044267| cellular protein metabolic process SERPINC1;SERPIND1;ALB GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 8458:[DB01183 DB02279] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02279|Benzoylformic Acid HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;HAO1;CYP3A4 8459:[DB01183 DB08338] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08338|19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one CSNK2A1 common genes common pathways GO:0006468| protein phosphorylation CREB1;CSNK2A1 GO:0007165| signal transduction ESR1;OPRD1;CSNK2A1;OPRM1;OPRK1;TLR4;CREB1 GO:0048511| rhythmic process CREB1;CSNK2A1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ESR1;CREB1 8460:[DB01183 DB04172] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04172|[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine PLAU common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;OPRK1;PLAU GO:0001666| response to hypoxia PLAU;CREB1 8461:[DB01183 DB06907] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 8462:[DB01183 DB04217] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04217|L-2-amino-3-butynoic acid CTH;sufS common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CTH GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CTH GO:1990830| CREB1;CTH 8463:[DB01183 DB05014] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;PDGFRB;TLR4;FGFR3 GO:0009636| response to toxin CES1;PDGFRB GO:0014070| response to organic cyclic compound UGT1A1;PDGFRB GO:0043627| response to estrogen stimulus OPRK1;PDGFRB;ESR1 GO:0007411| axon guidance CREB1;RET GO:0008584| male gonad development PDGFRB;ESR1 GO:0010628| positive regulation of gene expression RET;TLR4 GO:0048146| positive regulation of fibroblast proliferation PDGFRB;ESR1 GO:0030154| cell differentiation KDR;CREB1;FLT3 GO:0006468| protein phosphorylation FGFR1;FLT3;RET;FGFR3;PDGFRB;CREB1;KDR GO:0007568| aging CREB1;PDGFRB GO:0036120| PDGFRB;CREB1 GO:0032355| response to estradiol stimulus ESR1;PDGFRB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDGFRB;OPRD1;OPRM1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0007165| signal transduction RET;ESR1;OPRD1;OPRM1;OPRK1;TLR4;PDGFRB;CREB1 GO:0031100| organ regeneration UGT1A1;FLT3 GO:0010863| positive regulation of phospholipase C activity FGFR1;ESR1;PDGFRB GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0042493| response to drug RET;ABCB1;UGT1A1;CREB1 GO:0010629| negative regulation of gene expression ESR1;FGFR1;OPRD1;CREB1;KDR GO:0006355| regulation of transcription, DNA-dependent ESR1;FGFR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;RET GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0016032| viral reproduction CREB1;KDR GO:0006351| transcription, DNA-dependent CREB1;FGFR1;ESR1 GO:0042060| wound healing PDGFRB;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;FGFR1 GO:0042981| regulation of apoptotic process CREB1;FLT3;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PDGFRB GO:0043066| negative regulation of apoptotic process KDR;ALB;PDGFRB 8464:[DB01183 DB11590] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes ALB common pathways GO:0006811| ion transport ITPR1;FXYD2;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0009636| response to toxin CES1;SLC7A11;GPX1 GO:0055085| transmembrane transport SLCO1A2;ITPR1;ABCB1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0001666| response to hypoxia CREB1;ITPR1 GO:0008285| negative regulation of cell proliferation SOD2;OPRM1 GO:0051659| maintenance of mitochondrion location ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0006810| transport FXYD2;ABCB1 GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070588| calcium ion transmembrane transport OPRM1;ITPR1 GO:0098869| GSR;ALB;GPX1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;ITPR1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process SOD2;CYP2C8;GSR;GPX1;CYP3A4 GO:0035094| response to nicotine SLC7A11;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter SOD2;ESR1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process GPX1;ALB GO:0006629| lipid metabolic process CYP3A4;GPX1 8465:[DB01183 DB06481] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06481|Manitimus DHODH common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation UGT1A1;DHODH GO:0007595| lactation DHODH;CREB1 GO:0042493| response to drug DHODH;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHODH 8466:[DB01183 DB07015] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8467:[DB01183 DB00167] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ACADSB;CYP2C8 GO:0006629| lipid metabolic process ACADSB;CYP3A4 GO:0008152| metabolic process UGT1A1;BCAT2;CES1;BCAT1;ACADSB GO:1990830| CREB1;BCAT2 GO:0055085| transmembrane transport ABCB1;SLC16A10;SLCO1A2 8468:[DB01183 DB02459] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways GO:0045087| innate immune response CFB;TLR4 GO:0002376| immune system process TLR4;CFB 8469:[DB01183 DB00241] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007626| locomotory behavior CHRNA4;OPRM1;OPRK1 GO:0019233| sensory perception of pain OPRM1;OPRD1;CHRNA4;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIK2;CHRNA4;GRIA2;CHRNA7 GO:0035094| response to nicotine CREB1;CHRNA4;CHRNA7 GO:1901215| GABRB2;CREB1;GABRB3 GO:0007268| synaptic transmission OPRK1;GABRD;GABRB2;GABRA5;GABRG1;GRIA2;CHRNA4;GRIK2;OPRD1;GABRG2;OPRM1 GO:0042493| response to drug GABRG3;ABCB1;UGT1A1;CREB1 GO:0007165| signal transduction OPRM1;GABRE;GABRQ;OPRD1;GABRB1;ESR1;GABRA6;GRIA2;CHRNA4;GABRB3;CHRNA7;GABRA5;GABRD;CREB1;TLR4;GABRP;OPRK1 GO:1900273| CREB1;CHRNA7 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0006810| transport GABRB3;GRIK2;GABRA6;GABRA4;GABRA1;GABRG2;GABRB1;ABCB1;GABRD;GABRB2;GABRA3;GABRA5 GO:0007613| memory CREB1;CHRNA7 GO:0001666| response to hypoxia CREB1;CHRNA7;CHRNA4 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0055085| transmembrane transport GRIK2;SLCO1A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;CHRNA7 GO:0009636| response to toxin CES1;GABRB1 GO:0006811| ion transport GABRQ;GABRB1;GABRG2;SLCO1A2;GABRE;GABRA1;GABRA4;GRIK2;GABRA6;GRIA2;CHRNA4;GABRG3;CHRNA7;GABRB3;GABRA3;GABRA5;GABRG1;GABRP;GABRD;GABRB2;GABRA2 8470:[DB01183 DB02638] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways GO:0042711| maternal behavior AVPR1A;OPRK1 GO:0032609| interferon-gamma production AVPR2;TLR4 GO:0010033| response to organic substance AVPR1A;UGT1A1;CREB1 GO:0010628| positive regulation of gene expression AVPR2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration AVPR1B;OPRM1;AVPR1A;ESR1 GO:0007186| G-protein coupled receptor signaling pathway AVPR1B;OPRK1;AVPR2;AVPR1A;OPRM1;OPRD1 GO:0007165| signal transduction OPRK1;AVPR2;TLR4;CREB1;AVPR1B;ESR1;AVPR1A;OPRD1;OPRM1 GO:0032870| cellular response to hormone stimulus UGT1A1;AVPR1B;AVPR2;AVPR1A GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;TLR4 8471:[DB01183 DB05159] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05159|CCX915 CCR2 common genes common pathways GO:0032729| positive regulation of interferon-gamma production TLR4;CCR2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;CCR2 GO:0019233| sensory perception of pain OPRK1;CCR2;OPRM1;OPRD1 GO:0006955| immune response OPRK1;TLR4;CCR2;OPRD1 GO:0016032| viral reproduction CREB1;CCR2 GO:0006954| inflammatory response CCR2;TLR4 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process TLR4;CCR2 GO:0050729| positive regulation of inflammatory response TLR4;CCR2 GO:0007186| G-protein coupled receptor signaling pathway CCR2;OPRD1;OPRM1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;CCR2 GO:0007165| signal transduction CCR2;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 8472:[DB01183 DB06069] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06069|XMT-1001 TOP1 common genes common pathways GO:0007623| circadian rhythm TOP1;CREB1 GO:0016032| viral reproduction CREB1;TOP1 GO:0042493| response to drug TOP1;UGT1A1;CREB1;ABCB1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process CREB1;TOP1 8473:[DB01183 DB02074] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02074|Butenoic Acid FABP1 common genes common pathways GO:0098869| ALB;FABP1 GO:0071456| cellular response to hypoxia FABP1;OPRD1 GO:0043066| negative regulation of apoptotic process ALB;FABP1 8474:[DB01183 DB14033] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0097267| CYP2C9;CYP2C8 8475:[DB01183 DB05712] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05712|AZD-9684 CPB2 common genes common pathways GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CPB2 8476:[DB01183 DB00467] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;TOP2A;CREB1 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0048511| rhythmic process CREB1;TOP2A GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 8477:[DB01183 DB08837] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA9 GO:0007268| synaptic transmission KCNA1;OPRK1;OPRM1;OPRD1 GO:0015711| organic anion transport SLC22A5;SLC22A3;SLC22A4;SLCO1A2;SLC22A2;SLC22A1 GO:0007165| signal transduction OPRK1;CREB1;CHRNA9;TLR4;ESR1;OPRM1;OPRD1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA9 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;CHRNA9 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0055085| transmembrane transport SLC47A1;SLC22A8;SLC22A5;SLCO1A2;SLC22A4;SLC22A3;SLC22A2;KCNA1;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A3;SLC22A5;SLC47A1;SLC22A1;ABCB1;SLC22A2 GO:0006811| ion transport SLC22A1;CHRNA9;KCNA1;SLC22A2;SLC22A3;SLCO1A2;SLC22A4;SLC22A8;SLC22A5 GO:0009636| response to toxin CES1;SLC22A8 8478:[DB01183 DB00187] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00187|Esmolol ADRB1;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction OPRK1;ADRB1;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;ADRB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 8479:[DB01183 DB03336] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03336|BIA COMT common genes common pathways GO:0042493| response to drug COMT;UGT1A1;CREB1;ABCB1 GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0032496| response to lipopolysaccharide COMT;UGT1A1;TLR4;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;COMT GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1;COMT GO:0043627| response to estrogen stimulus COMT;OPRK1;ESR1 8480:[DB01183 DB12693] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0016032| viral reproduction CREB1;HTR2A GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0042493| response to drug HTR2A;ABCB1;UGT1A1;CREB1 GO:0007268| synaptic transmission HTR2A;OPRM1;OPRD1;OPRK1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;HTR2A;OPRM1;OPRD1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;HTR2A GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;TLR4 GO:0007165| signal transduction HTR2A;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0007610| behavior OPRK1;HTR2A GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory HTR2A;CREB1 GO:0007568| aging CREB1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;HTR2A GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 8481:[DB01183 DB06817] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06817|Raltegravir pol;UGT1A1 common genes UGT1A1 common pathways GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0010033| response to organic substance CREB1;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1;CES1 GO:1904224| UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0001889| liver development UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 8482:[DB01183 DB04715] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04715|IMIDAZOPYRIDAZIN 1 PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity PIM1;ESR1 GO:0006468| protein phosphorylation CREB1;PIM1 8483:[DB01183 DB06892] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;MAP2K1;CREB1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1;MAP2K1 GO:0042981| regulation of apoptotic process ESR1;MAP2K1;CREB1 GO:0000187| activation of MAPK activity TLR4;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K1;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;MAP2K1 GO:0010628| positive regulation of gene expression TLR4;MAP2K1 GO:0006468| protein phosphorylation CREB1;MAP2K1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;MAP2K1;OPRM1;OPRD1;ESR1 8484:[DB01183 DB05553] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05553|Regrelor P2RY12 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1;P2RY12 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;P2RY12;OPRK1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;P2RY12;TLR4;CREB1;OPRK1 GO:0070588| calcium ion transmembrane transport P2RY12;OPRM1 GO:0043491| protein kinase B signaling cascade P2RY12;CREB1 GO:0051924| regulation of calcium ion transport OPRD1;P2RY12 8485:[DB01183 DB14031] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14031|Tretamine BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0042493| response to drug ABCB1;CREB1;BCHE;UGT1A1 8486:[DB01183 DB00013] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0044267| cellular protein metabolic process PLG;ALB GO:0050769| positive regulation of neurogenesis LRP2;OPRM1 GO:0008285| negative regulation of cell proliferation PLG;OPRM1 GO:0001666| response to hypoxia PLAT;PLAU;CREB1 GO:0042359| vitamin D metabolic process LRP2;CYP3A4 GO:0008584| male gonad development LRP2;ESR1 GO:0050729| positive regulation of inflammatory response TLR4;SERPINE1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;PLAU;OPRK1;PLAUR;TLR4;CREB1 GO:0032757| positive regulation of interleukin-8 production SERPINE1;TLR4 GO:0006898| receptor-mediated endocytosis LRP2;ALB GO:0060068| vagina development LRP2;ESR1 GO:0042060| wound healing SERPINB2;OPRM1 GO:0007623| circadian rhythm SERPINE1;CREB1 GO:0006629| lipid metabolic process LRP2;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;PLAUR;SERPINB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;SERPINE1;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;SERPINE1 GO:0050829| defense response to Gram-negative bacterium TLR4;SERPINE1 GO:0002576| platelet degranulation ALB;PLG;SERPINE1 8487:[DB01183 DB08672] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8488:[DB01183 DB01863] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01863|Inositol 1,3,4,5-Tetrakisphosphate AKT1;PLEKHA4;BTK;DAPP1;ITPKA;CYTH2;CYTH3;PDPK1 common genes common pathways GO:1901215| CREB1;AKT1 GO:0043491| protein kinase B signaling cascade CREB1;AKT1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;AKT1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;BTK;PDPK1;CREB1 GO:0032094| response to food OPRM1;AKT1 GO:0045893| positive regulation of transcription, DNA-dependent AKT1;ESR1;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;BTK GO:0006954| inflammatory response AKT1;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;AKT1 GO:0000060| protein import into nucleus, translocation OPRD1;AKT1 GO:0097190| apoptotic signaling pathway TLR4;BTK GO:0060079| regulation of excitatory postsynaptic membrane potential AKT1;OPRM1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;AKT1 GO:0006351| transcription, DNA-dependent CREB1;PDPK1;ESR1;BTK GO:0046889| positive regulation of lipid biosynthetic process AKT1;CREB1 GO:1990090| AKT1;CREB1 GO:0045087| innate immune response TLR4;BTK GO:0042981| regulation of apoptotic process CREB1;ESR1;AKT1 GO:0071260| cellular response to mechanical stimulus AKT1;TLR4 GO:0043065| positive regulation of apoptotic process AKT1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;AKT1;ESR1 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;AKT1 GO:0043066| negative regulation of apoptotic process AKT1;ALB GO:0002755| MyD88-dependent toll-like receptor signaling pathway BTK;TLR4 GO:0010033| response to organic substance UGT1A1;CREB1;AKT1;BTK GO:0045600| positive regulation of fat cell differentiation AKT1;CREB1 GO:0030154| cell differentiation CREB1;AKT1 GO:0006468| protein phosphorylation PDPK1;CREB1;ITPKA;AKT1;BTK GO:0071456| cellular response to hypoxia OPRD1;AKT1 GO:0007568| aging AKT1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway AKT1;OPRD1;OPRM1;OPRK1 GO:0071363| cellular response to growth factor stimulus AKT1;OPRD1;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;AKT1 GO:0007165| signal transduction ITPKA;OPRK1;CREB1;TLR4;DAPP1;OPRM1;AKT1;OPRD1;ESR1 GO:0002376| immune system process TLR4;BTK GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;AKT1;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;AKT1;BTK 8489:[DB01183 DB07176] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR GO:0006810| transport TTR;ABCB1 8490:[DB01183 DB04648] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04648|S-propylamine-L-cysteine ARG1 common genes common pathways GO:0007568| aging ARG1;CREB1 GO:0048545| response to steroid hormone stimulus ARG1;UGT1A1 GO:0002376| immune system process TLR4;ARG1 GO:0042493| response to drug ARG1;ABCB1;UGT1A1;CREB1 GO:0001889| liver development UGT1A1;ARG1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;ARG1 GO:0045087| innate immune response ARG1;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;CREB1 8491:[DB01183 DB00137] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00137|Lutein ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 8492:[DB01183 DB08954] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0006811| ion transport GRIN2B;SLCO1A2;GRIN1 GO:0008344| adult locomotory behavior GRIN1;OPRD1 GO:1904646| TLR4;GRIN1 GO:1903428| TLR4;GRIN1 GO:0006810| transport GRIN2B;ABCB1 GO:0007613| memory CREB1;GRIN1 GO:0007268| synaptic transmission OPRK1;GRIN2B;OPRD1;OPRM1 GO:0043278| response to morphine OPRM1;GRIN1;OPRK1 GO:0008542| visual learning GRIN1;CREB1 GO:0019233| sensory perception of pain OPRK1;OPRD1;GRIN1;OPRM1 GO:0045471| response to ethanol GRIN2B;OPRM1;GRIN1;OPRK1;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIN1;GRIN2B GO:0043065| positive regulation of apoptotic process GRIN1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;CREB1;TLR4 8493:[DB01183 DB00505] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;CHRM3;CHRM2;CHRM1;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;OPRM1;OPRD1;CHRM1;CHRM2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CHRM2 GO:0007586| digestion CHRM3;UGT1A1 8494:[DB01183 DB09499] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09499|Thiosulfuric acid TST common genes common pathways GO:0030855| epithelial cell differentiation TST;CES1 8495:[DB01183 DB00166] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;POR GO:0006805| xenobiotic metabolic process CYP3A4;CES1;POR;CYP2C8 GO:0006629| lipid metabolic process LIPT1;CYP3A4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;LIAS;OPRM1 GO:0006954| inflammatory response LIAS;TLR4 GO:0042493| response to drug POR;ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;POR;CYP2C8 GO:0006810| transport SLC5A6;ABCB1 GO:0007584| response to nutrient POR;UGT1A1 GO:0006811| ion transport SLCO1A2;SLC5A6 GO:0055085| transmembrane transport SLC5A6;ABCB1;SLCO1A2 8496:[DB01183 DB04149] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways GO:0007165| signal transduction PDE4B;OPRK1;CREB1;TLR4;ESR1;OPRM1;PDE4D;OPRD1 GO:0007568| aging PDE4D;CREB1 GO:0007186| G-protein coupled receptor signaling pathway PDE4B;OPRK1;OPRM1;OPRD1;PDE4D GO:0071222| cellular response to lipopolysaccharide OPRK1;PDE4B;TLR4;PDE4D GO:0032729| positive regulation of interferon-gamma production PDE4B;TLR4;PDE4D 8497:[DB01183 DB08370] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;OPRK1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;GSTP1;CYP2C8 GO:0008152| metabolic process UGT1A1;GSTP1;CES1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0045471| response to ethanol OPRM1;OPRK1;GSTP1;UGT1A1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0098869| GSTP1;ALB GO:0032355| response to estradiol stimulus ESR1;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0009636| response to toxin GSTP1;CES1 8498:[DB01183 DB00837] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0007194| negative regulation of adenylate cyclase activity OPRM1;GABBR1 GO:0006811| ion transport SLCO1A2;GABRA1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;OPRM1;GABBR1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;GABBR1 GO:0006810| transport ABCB1;GABRA1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;GABBR1;OPRM1;OPRD1 8499:[DB01183 DB06785] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06785|Ganirelix GNRHR common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;GNRHR;TLR4;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;GNRHR;OPRK1 8500:[DB01183 DB11235] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007165| signal transduction CHRM4;OPRK1;CHRM3;CREB1;TLR4;OPRM1;CHRM5;HRH1;OPRD1;ESR1;CHRM1;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway CHRM4;OPRK1;CHRM3;CHRM5;OPRM1;OPRD1;HRH1;CHRM1;CHRM2 GO:0007613| memory HRH1;CREB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0007586| digestion UGT1A1;CHRM3 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;HRH1;OPRM1;OPRK1 GO:0006954| inflammatory response HRH1;TLR4 GO:0008542| visual learning CREB1;HRH1 8501:[DB01183 DB13620] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC12A1 GO:0006811| ion transport FXYD2;ATP4A;SLCO1A2;ATP4B;ATP1A1;SLC12A1 GO:0006810| transport SLC12A1;FXYD2;ATP4A;ABCB1 GO:0042493| response to drug ATP1A1;CREB1;UGT1A1;ABCB1 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ATP4B;OPRM1 8502:[DB01183 DB01191] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01191|Dexfenfluramine SLC6A4;HTR2C;CYP2D6;CYP1A2;CYP2E1 common genes common pathways GO:0045600| positive regulation of fat cell differentiation HTR2C;CREB1 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0009636| response to toxin SLC6A4;CES1 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2C;TLR4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP1A2;CYP3A4 GO:0007165| signal transduction OPRK1;HTR2C;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0097267| CYP2C8;CYP1A2 GO:0007610| behavior HTR2C;OPRK1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C8;CYP2D6;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;HTR2C;OPRK1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;SLC6A4 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0007613| memory CREB1;SLC6A4 GO:0042493| response to drug CYP1A2;CYP2E1;SLC6A4;UGT1A1;CREB1;ABCB1;HTR2C GO:0007268| synaptic transmission HTR2C;OPRK1;OPRM1;OPRD1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0007626| locomotory behavior HTR2C;OPRK1;OPRM1 GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP2E1;CYP3A4;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2C;OPRK1;ESR1;OPRM1;OPRD1 GO:0045471| response to ethanol UGT1A1;OPRK1;CYP2E1;OPRM1 8503:[DB01183 DB05137] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways GO:0035094| response to nicotine CREB1;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;OPRM1;CHRNA10;CHRNA9 GO:0006811| ion transport CHRNA10;CHRNA9;CHRNA7;SLCO1A2 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;TLR4 GO:0001666| response to hypoxia CHRNA7;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA9;CHRNA10;ESR1;OPRM1 GO:0007613| memory CREB1;CHRNA7 GO:1900273| CREB1;CHRNA7 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1;CHRNA10;CHRNA9 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0007165| signal transduction OPRK1;CHRNA10;TLR4;CREB1;CHRNA9;CHRNA7;ESR1;OPRD1;OPRM1 8504:[DB01183 DB03496] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03496|Alvocidib CDK2;CDK5;CDK9;CDK1;CDK6;EGFR;CDK4;CDK8;CDK7;PYGM;PYGB;PYGL;UGT1A1;ABCG2 common genes UGT1A1 common pathways GO:0071363| cellular response to growth factor stimulus EGFR;CREB1;OPRD1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0050821| protein stabilization CDK7;CREB1 GO:0014002| astrocyte development TLR4;CDK6 GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0071392| cellular response to estradiol stimulus ESR1;EGFR;UGT1A1 GO:0006468| protein phosphorylation CDK2;CREB1;CDK6;CDK7;CDK5;EGFR;CDK9;CDK4;CDK1;CDK8 GO:0030154| cell differentiation CREB1;CDK6 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0006810| transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0031100| organ regeneration UGT1A1;CDK1;CDK4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;EGFR;ESR1;OPRM1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;EGFR GO:0007165| signal transduction OPRK1;EGFR;CDK6;CREB1;TLR4;ESR1;OPRM1;CDK4;OPRD1 GO:0007409| axonogenesis CDK5;CREB1 GO:0014070| response to organic cyclic compound EGFR;UGT1A1;CDK1 GO:0009636| response to toxin CES1;CDK1;CDK4 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0055085| transmembrane transport SLCO1A2;ABCG2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;EGFR;OPRM1 GO:0006366| transcription from RNA polymerase II promoter CDK9;ESR1;CDK7;CREB1 GO:0000086| G2/M transition of mitotic cell cycle CDK7;CDK2;ABCB1;CDK1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0030855| epithelial cell differentiation CES1;CDK1 GO:0042220| response to cocaine OPRM1;OPRK1;CDK5 GO:0000187| activation of MAPK activity TLR4;CDK1 GO:0048146| positive regulation of fibroblast proliferation ESR1;CDK4;CDK6;EGFR GO:0010628| positive regulation of gene expression TLR4;CDK1 GO:1904646| TLR4;CDK5 GO:0048511| rhythmic process CREB1;CDK5 GO:0007584| response to nutrient UGT1A1 GO:0014823| response to activity CREB1;CDK1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;CDK6 GO:0010033| response to organic substance CDK4;UGT1A1;CDK2;CREB1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0016579| protein deubiquitination CDK1;ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1 GO:0051552| flavone metabolic process UGT1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;EGFR GO:0007623| circadian rhythm CREB1;EGFR;CDK4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042060| wound healing OPRM1;EGFR GO:1904224| UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CDK5 GO:0045471| response to ethanol CDK1;OPRM1;UGT1A1;OPRK1 GO:0001889| liver development UGT1A1;EGFR GO:0019233| sensory perception of pain OPRK1;CDK5;OPRM1;OPRD1 GO:0006351| transcription, DNA-dependent CREB1;CDK7;ESR1;CDK9;CDK8 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;CDK4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CDK9;CDK8;TLR4;CREB1;CDK7;EGFR GO:0043065| positive regulation of apoptotic process CREB1;CDK4 GO:0043066| negative regulation of apoptotic process ALB;EGFR;CDK1 GO:0048148| behavioral response to cocaine CDK5;OPRK1 GO:0008152| metabolic process PYGB;PYGL;UGT1A1;CES1;PYGM GO:0070266| necroptosis PYGL;TLR4 GO:0042981| regulation of apoptotic process CDK5;CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;ESR1 GO:0007586| digestion UGT1A1 GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0042594| response to starvation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0006355| regulation of transcription, DNA-dependent CDK8;ESR1;CDK9;CREB1;CDK7 GO:0042493| response to drug CDK9;CDK4;CDK1;ABCG2;ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission OPRK1;CDK5;OPRM1;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1;CDK7;CDK2 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:1901215| CREB1;CDK5 GO:0052695| cellular glucuronidation UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter CDK9;ESR1;CDK4;CDK1;CDK8;CDK7 GO:0008210| estrogen metabolic process UGT1A1 GO:0008542| visual learning CREB1;CDK5 8505:[DB01183 DB04459] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways GO:0002576| platelet degranulation CFD;ALB GO:0045087| innate immune response CFD;TLR4 GO:0002376| immune system process CFD;TLR4 8506:[DB01183 DB07101] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07101|PD-0325901 MAP2K1 common genes common pathways GO:0010629| negative regulation of gene expression MAP2K1;OPRD1;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;MAP2K1;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K1;TLR4 GO:0000187| activation of MAPK activity TLR4;MAP2K1 GO:0010628| positive regulation of gene expression TLR4;MAP2K1 GO:0008285| negative regulation of cell proliferation OPRM1;MAP2K1 GO:0006468| protein phosphorylation CREB1;MAP2K1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;MAP2K1;CREB1;TLR4;OPRK1 8507:[DB01183 DB04754] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug UGT1A1;PNP;CREB1;ABCB1 GO:0006955| immune response OPRD1;OPRK1;PNP;TLR4 8508:[DB01183 DB03695] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03695|Piritrexim DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 8509:[DB01183 DB02845] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02845|Methylphosphinic Acid BCHE;ACHE;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0042493| response to drug ABCB1;UGT1A1;BCHE;CREB1 8510:[DB01183 DB02877] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02877|Arotinoid acid RARB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;RARB;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARB GO:0043401| steroid hormone mediated signaling pathway ESR1;RARB GO:0006351| transcription, DNA-dependent CREB1;RARB;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RARB GO:0043065| positive regulation of apoptotic process RARB;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;RARB GO:0043066| negative regulation of apoptotic process RARB;ALB GO:0008285| negative regulation of cell proliferation OPRM1;RARB GO:0007165| signal transduction OPRM1;OPRD1;ESR1;RARB;OPRK1;CREB1;TLR4 8511:[DB01183 DB08454] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways GO:0043066| negative regulation of apoptotic process CAMK1D;ALB GO:0008152| metabolic process CAMK1D;CES1;UGT1A1 GO:0043065| positive regulation of apoptotic process CAMK1D;CREB1 GO:0006954| inflammatory response TLR4;CAMK1D GO:0006468| protein phosphorylation CAMK1D;CREB1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;CAMK1D 8512:[DB01183 DB06706] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0055085| transmembrane transport SLC18A2;SLCO1A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;OPRM1 GO:0009636| response to toxin CES1;SLC18A2 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;ADRA1A GO:0007568| aging ADRA1A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRA1A;OPRK1 GO:0007165| signal transduction ADRA1A;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0042493| response to drug UGT1A1;CREB1;ADRA1A;ABCB1 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;SLC18A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ADRA1A;ESR1;OPRD1;OPRM1 GO:0007626| locomotory behavior OPRM1;SLC18A2;OPRK1 8513:[DB01183 DB02373] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02373|Adenosine Monotungstate FHIT common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;FHIT;CREB1 GO:0006351| transcription, DNA-dependent CREB1;FHIT;ESR1 8514:[DB01183 DB11792] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A43;CYP3A7;CYP3A4;CYP3A5;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP3A7;CYP3A5;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP2C8;CYP3A7;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;UGT1A1;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 8515:[DB01183 DB03856] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03856|L-Eflornithine ODC1 common genes common pathways 8516:[DB01183 DB01120] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes ALB common pathways GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C19;CYP2C8 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0007613| memory CREB1;ABCC8 GO:0030154| cell differentiation VEGFA;CREB1 GO:0071456| cellular response to hypoxia VEGFA;OPRD1 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19;UGT1A1;CYP2C9 GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ABCC8;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;OPRD1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0044267| cellular protein metabolic process ALB GO:0032868| response to insulin stimulus OPRK1;ABCC8 GO:0055085| transmembrane transport ABCB1;SLCO1A2;ABCC8 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;VEGFA;TLR4 GO:0001666| response to hypoxia CREB1;VEGFA GO:0010628| positive regulation of gene expression TLR4;VEGFA GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;ABCC8 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0043066| negative regulation of apoptotic process ALB;VEGFA GO:0002576| platelet degranulation ALB;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;VEGFA GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:1900745| OPRK1;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0060749| mammary gland alveolus development ESR1;VEGFA GO:0010629| negative regulation of gene expression VEGFA;OPRD1;ESR1;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0042493| response to drug ABCC8;ABCB1;CREB1;UGT1A1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2C19;CYP2C8;CYP3A4 GO:0008542| visual learning ABCC8;CREB1 GO:0032760| positive regulation of tumor necrosis factor production ABCC8;TLR4 GO:0007595| lactation VEGFA;CREB1 8517:[DB01183 DB07339] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP3A4;NQO2;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;NQO2;CYP2C8 8518:[DB01183 DB06471] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06471|Naxifylline ADORA1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;ADORA1 GO:0001666| response to hypoxia CREB1;ADORA1 GO:0051930| regulation of sensory perception of pain ADORA1;OPRK1;OPRD1;OPRM1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;ADORA1;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADORA1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;ADORA1 GO:0006954| inflammatory response ADORA1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0097190| apoptotic signaling pathway TLR4;ADORA1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;ADORA1 8519:[DB01183 DB00423] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00423|Methocarbamol CA1 common genes common pathways 8520:[DB01183 DB02776] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02776|1-Hexadecanosulfonic Acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response ESR1;FABP4;TLR4 GO:0050729| positive regulation of inflammatory response FABP4;TLR4 8521:[DB01183 DB06726] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:1904646| ADRB2;TLR4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0042755| eating behavior OPRM1;OPRD1;ADRB3;OPRK1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRD1;OPRM1;ADRB2;ESR1;TLR4;CREB1;ADRB1;OPRK1;ADRB3 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADRB2;ADRB1;OPRK1;ADRB3 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0007568| aging CREB1;ADRB3 8522:[DB01183 DB01933] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways GO:0006468| protein phosphorylation CREB1;PDPK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PDPK1 GO:0006351| transcription, DNA-dependent CREB1;PDPK1;ESR1 8523:[DB01183 DB03606] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4;PDE4B GO:0071222| cellular response to lipopolysaccharide TLR4;PDE4B;OPRK1;PDE4D GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PDE4D;PDE4B;OPRK1 GO:0007568| aging PDE4D;CREB1 GO:0007165| signal transduction PDE4B;OPRK1;CREB1;TLR4;ESR1;OPRM1;OPRD1;PDE4D 8524:[DB01183 DB11477] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0007165| signal transduction OPRK1;ADRA2A;TLR4;CREB1;ADRA2B;ADRA2C;ESR1;OPRD1;OPRM1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRA2A;ADRA2B;ADRA2C;OPRD1;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1;ADRA2C 8525:[DB01183 DB03977] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CALM1;OPRD1;OPRM1;OPRK1 GO:0055085| transmembrane transport ABCB1;CALM1;SLCO1A2 GO:0002576| platelet degranulation CALM1;ALB GO:0055114| oxidation-reduction process CYP3A4;CYCS;CYP2C8 8526:[DB01183 DB00070] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00070|Hyaluronidase TGFB1;ALB common genes ALB common pathways GO:0043491| protein kinase B signaling cascade CREB1;TGFB1 GO:0043687| post-translational protein modification ALB GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;TGFB1 GO:0042493| response to drug TGFB1;ABCB1;UGT1A1;CREB1 GO:0010629| negative regulation of gene expression CREB1;TGFB1;OPRD1;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TGFB1 GO:0006954| inflammatory response TGFB1;TLR4 GO:0000060| protein import into nucleus, translocation OPRD1;TGFB1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0042060| wound healing OPRM1;TGFB1 GO:0071260| cellular response to mechanical stimulus TLR4;TGFB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TGFB1 GO:0042981| regulation of apoptotic process CREB1;ESR1;TGFB1 GO:0071560| cellular response to transforming growth factor beta stimulus TGFB1;CREB1 GO:0043066| negative regulation of apoptotic process ALB GO:0031663| lipopolysaccharide-mediated signaling pathway TGFB1;TLR4 GO:0002576| platelet degranulation TGFB1;ALB GO:0043065| positive regulation of apoptotic process TGFB1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TGFB1;TLR4;CREB1 GO:0009314| response to radiation TGFB1;OPRM1;OPRK1 GO:0001895| retina homeostasis ALB GO:0007179| transforming growth factor beta receptor signaling pathway TGFB1;CREB1 GO:0044267| cellular protein metabolic process ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;TGFB1;OPRM1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound TGFB1;UGT1A1 GO:0030879| mammary gland development CREB1;TGFB1 GO:0008285| negative regulation of cell proliferation TGFB1;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;TGFB1 GO:0010628| positive regulation of gene expression TLR4;TGFB1 GO:0001666| response to hypoxia TGFB1;CREB1 GO:0048146| positive regulation of fibroblast proliferation TGFB1;ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0032700| negative regulation of interleukin-17 production TLR4;TGFB1 GO:0007568| aging TGFB1;CREB1 GO:0043069| negative regulation of programmed cell death ALB GO:1990314| CREB1;TGFB1 GO:0006468| protein phosphorylation TGFB1;CREB1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0032355| response to estradiol stimulus ESR1;TGFB1 GO:0051659| maintenance of mitochondrion location ALB GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;TGFB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TGFB1;OPRD1 GO:0098869| ALB GO:0031100| organ regeneration UGT1A1;TGFB1 GO:0006898| receptor-mediated endocytosis ALB GO:1903799| ESR1;TGFB1 8527:[DB01183 DB01352] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA4;GRIA2;CHRNA7;OPRM1;GRIK2 GO:0019233| sensory perception of pain OPRD1;OPRM1;CHRNA4;OPRK1 GO:0007626| locomotory behavior OPRK1;CHRNA4;OPRM1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0007268| synaptic transmission OPRK1;GABRA5;GRIA2;CHRNA4;GRIK2;OPRD1;OPRM1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0035094| response to nicotine CHRNA7;CHRNA4;CREB1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007613| memory CHRNA7;CREB1 GO:0006810| transport GABRA4;GABRA6;GRIK2;GABRA1;ABCB1;GABRA3;GABRA5 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:1900273| CHRNA7;CREB1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRK1;GABRA5;CREB1;TLR4;CHRNA4;GRIA2;CHRNA7;OPRM1;OPRD1;GABRA6;ESR1 GO:0006811| ion transport GABRA2;GABRA3;GABRA5;CHRNA7;CHRNA4;GRIA2;GABRA4;GABRA6;GRIK2;GABRA1;SLCO1A2 GO:0002933| CYP3A4;CYP2C8 GO:0055085| transmembrane transport SLCO1A2;GRIK2;ABCB1 GO:0036378| CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CHRNA7;TLR4 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0001666| response to hypoxia CREB1;CHRNA7;CHRNA4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 8528:[DB01183 DB06468] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;MPO GO:0043065| positive regulation of apoptotic process CREB1;SLC9A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;ESR1;CREB1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;MPO;SLC9A1 GO:0071260| cellular response to mechanical stimulus SLC9A1;TLR4 GO:0032094| response to food MPO;OPRM1 GO:0042742| defense response to bacterium TLR4;MPO GO:0055114| oxidation-reduction process CYP3A4;MPO;CYP2C8 GO:0030154| cell differentiation CREB1;SLC9A1 GO:0071456| cellular response to hypoxia OPRD1;SLC9A1 GO:0007568| aging CREB1;MPO GO:0006811| ion transport SLC9A1;SLCO1A2 GO:0051930| regulation of sensory perception of pain SLC9A1;OPRD1;OPRM1;OPRK1 GO:0014070| response to organic cyclic compound SLC9A1;UGT1A1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC9A1 8529:[DB01183 DB07638] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes ESR1 common pathways GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRK1;ESR2;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:1903799| ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0032355| response to estradiol stimulus ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0060065| uterus development ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR2;ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 8530:[DB01183 DB06833] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways GO:0032355| response to estradiol stimulus ESRRA;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;ESRRA GO:0006351| transcription, DNA-dependent CREB1;ESRRA;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESRRA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESRRA GO:0006355| regulation of transcription, DNA-dependent ESRRA;CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESRRA;CREB1 8531:[DB01183 DB13932] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13932|Voretigene Neparvovec RPE65 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;RPE65;CYP3A4 GO:0007623| circadian rhythm RPE65;CREB1 GO:0001895| retina homeostasis ALB;RPE65 8532:[DB01183 DB07967] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07967|9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 8533:[DB01183 DB06358] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06358|Iclaprim DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHFR 8534:[DB01183 DB02306] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 8535:[DB01183 DB08089] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08089|LGD-2226 AR common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;AR;ESR1;OPRM1;OPRD1 GO:0006810| transport ABCB1;AR GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0008584| male gonad development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 8536:[DB01183 DB01044] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes ALB common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB 8537:[DB01183 DB04012] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CREB1 GO:0070588| calcium ion transmembrane transport FKBP1A;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A 8538:[DB01183 DB02557] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02557|Phosphoramidon MME;KEL common genes common pathways GO:0008361| regulation of cell size CREB1;KEL GO:0019233| sensory perception of pain OPRK1;OPRM1;MME;OPRD1 8539:[DB01183 DB04281] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation UGT1A1;DHODH GO:0042493| response to drug DHODH;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0007595| lactation CREB1;DHODH GO:0014070| response to organic cyclic compound DHODH;UGT1A1 8540:[DB01183 DB05171] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05171|E-2012 APH1A;PSENEN common genes common pathways GO:0043065| positive regulation of apoptotic process PSENEN;CREB1;APH1A 8541:[DB01183 DB03332] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03332|5,6-Cyclic-Tetrahydropteridine NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS3 GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 8542:[DB01183 DB04894] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes CYP3A4 common pathways GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0050671| positive regulation of lymphocyte proliferation TLR4;TACR1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0019233| sensory perception of pain OPRK1;OPRD1;TACR1;OPRM1 GO:0042737| drug catabolic process CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;TACR1;OPRM1;OPRD1;ESR1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;TACR1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1;SSTR2 GO:0007586| digestion SSTR2;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0042594| response to starvation UGT1A1;SSTR2 GO:0006629| lipid metabolic process CYP3A4 GO:0007268| synaptic transmission OPRK1;TACR1;OPRM1;OPRD1;SSTR5 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0071385| cellular response to glucocorticoid stimulus SSTR2;UGT1A1;SSTR5 GO:0006954| inflammatory response TACR1;TLR4 GO:0035094| response to nicotine CREB1;TACR1 GO:0043278| response to morphine OPRM1;TACR1;OPRK1 GO:0046887| positive regulation of hormone secretion TACR1;CREB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway SSTR2;OPRK1;OPRD1;OPRM1;TACR1;SSTR5 GO:0032355| response to estradiol stimulus TACR1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;SSTR2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;TACR1 GO:0071392| cellular response to estradiol stimulus SSTR2;UGT1A1;ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TACR1;SSTR5;TLR4;CREB1;SSTR2;OPRK1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0014070| response to organic cyclic compound TACR1;UGT1A1 GO:0002933| CYP2C8;CYP3A4 GO:0042755| eating behavior OPRK1;TACR1;OPRM1;OPRD1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008285| negative regulation of cell proliferation SSTR2;OPRM1;SSTR5 GO:0007584| response to nutrient SSTR2;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;SSTR5;SSTR2 8543:[DB01183 DB00772] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2B6;CYP2C8 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;BCHE;CREB1 GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C8;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2B6;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2B6;CYP2C8 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1;CYP2B6 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0017144| drug metabolic process CYP2B6;UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 8544:[DB01183 DB03760] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03760|Dihydrolipoic Acid GCSH;DLAT;PDK3 common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;DLAT GO:0071398| cellular response to fatty acid PDK3;CREB1 8545:[DB01183 DB07135] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8546:[DB01183 DB01206] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CES1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 8547:[DB01183 DB07525] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways GO:0010863| positive regulation of phospholipase C activity ESR1;FGFR1 GO:0006468| protein phosphorylation CREB1;FGFR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;FGFR1 GO:0006355| regulation of transcription, DNA-dependent FGFR1;ESR1;CREB1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;FGFR1;ESR1 8548:[DB01183 DB06993] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8549:[DB01183 DB05667] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05667|Levoketoconazole CYP11B1;CYP51A1 common genes common pathways GO:0006695| cholesterol biosynthetic process CYP51A1;CES1 GO:0006629| lipid metabolic process CYP3A4;CYP11B1;CYP51A1 GO:0055114| oxidation-reduction process CYP11B1;CYP51A1;CYP3A4;CYP2C8 GO:0006955| immune response OPRK1;TLR4;OPRD1;CYP11B1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP51A1;CYP11B1 GO:0032870| cellular response to hormone stimulus UGT1A1;CYP11B1 8550:[DB01183 DB06184] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06184|AEG35156 XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process XIAP;ALB GO:0050727| regulation of inflammatory response TLR4;XIAP;ESR1 8551:[DB01183 DB02919] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHFR GO:0051000| positive regulation of nitric-oxide synthase activity DHFR;ESR1 8552:[DB01183 DB01131] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP2D6;CYP3A4 GO:0097267| CYP2C8;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6;UGT1A1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C9;CYP2C8;CYP2C19;CYP2D6 GO:0042493| response to drug CYP2E1;CREB1;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;DHFR;CYP2C9;CYP2C19;CYP2C8;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CES1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2E1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0042737| drug catabolic process CYP3A4;CYP2D6;CYP2C9 GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1;UGT1A1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 8553:[DB01183 DB07141] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHFR GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 8554:[DB01183 DB05078] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05078|AER001 IL4R;IL13RA2 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;IL4R;IL13RA2;CREB1;TLR4;OPRK1 GO:0043032| positive regulation of macrophage activation TLR4;IL4R GO:0002376| immune system process TLR4;IL4R GO:0043627| response to estrogen stimulus OPRK1;ESR1;IL4R GO:0006955| immune response OPRK1;TLR4;OPRD1;IL4R 8555:[DB01183 DB00572] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0035094| response to nicotine CHRNB2;CREB1;CHRNA4 GO:0008542| visual learning CHRNB2;CREB1 GO:0007268| synaptic transmission OPRK1;GLRA1;CHRNA4;OPRM1;OPRD1 GO:0007586| digestion CHRM3;UGT1A1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0033603| positive regulation of dopamine secretion CHRNB2;OPRK1 GO:0007626| locomotory behavior OPRK1;CHRNB2;CHRNA4;OPRM1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRA1;OPRM1;OPRD1 GO:0019233| sensory perception of pain OPRD1;OPRM1;CHRNA4;CHRNB2;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;CHRNB2;CHRNA4;OPRM1 GO:0045471| response to ethanol CHRNB2;UGT1A1;OPRK1;OPRM1 GO:0071294| cellular response to zinc ion GLRA1;CREB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CHRM2 GO:0030890| positive regulation of B cell proliferation CHRNB2;TLR4 GO:0001666| response to hypoxia CHRNA4;CHRNB2;CREB1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2;ABCB11 GO:0042220| response to cocaine OPRK1;CHRNB2;OPRM1 GO:0055085| transmembrane transport ABCB1;ABCB11;SLCO1A2 GO:0006811| ion transport GLRA1;CHRNB2;SLCO1A2;CHRNA4 GO:0007165| signal transduction OPRM1;CHRM5;OPRD1;CHRM1;ESR1;CHRM2;CHRNA4;CHRNB2;CHRM3;CREB1;TLR4;CHRM4;OPRK1 GO:0006810| transport ABCB1;ABCB11 GO:0007613| memory CHRNB2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway CHRM4;OPRK1;CHRM3;OPRM1;CHRM5;OPRD1;CHRM1;CHRM2 8556:[DB01183 DB05332] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05332|Romiplostim MPL common genes common pathways 8557:[DB01183 DB05339] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05339|MN-305 HTR1A common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;HTR1A;OPRK1;CREB1;TLR4 GO:0007610| behavior HTR1A;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;HTR1A;OPRK1 8558:[DB01183 DB07036] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR2;ESR1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;ESR2;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0006351| transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TLR4;CREB1;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 8559:[DB01183 DB00110] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:1904646| TLR4;FCGR2B GO:0007165| signal transduction OPRK1;FCGR1A;TLR4;FCGR2B;CREB1;OPRD1;FCGR2C;OPRM1;ESR1 GO:0002376| immune system process C1QC;C1QA;C1R;C1QB;TLR4;FCGR2A;FCGR1A GO:0006898| receptor-mediated endocytosis FCGR1A;ALB;FCGR2B GO:0009617| response to bacterium FCGR2B;TLR4 GO:0006954| inflammatory response TLR4;FCGR2B GO:0006955| immune response OPRK1;FCGR1A;TLR4;FCGR2B;FCGR3B;C1R;C1QC;FCGR3A;OPRD1;FCGR2C GO:0016032| viral reproduction FCGR2B;CREB1 GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0045087| innate immune response C1R;C1QB;TLR4;FCGR1A;C1QC;C1QA 8560:[DB01183 DB01094] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1;SLCO1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A2;SOAT1;CYP3A4;SOAT2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0042493| response to drug CYP1A2;ABCB1;ABCG2;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006629| lipid metabolic process MTTP;SOAT2;CYP3A4;SOAT1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 8561:[DB01183 DB05139] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05139|CR002 PDGFD common genes common pathways GO:0071560| cellular response to transforming growth factor beta stimulus PDGFD;CREB1 GO:0036120| PDGFD;CREB1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PDGFD GO:0070374| positive regulation of ERK1 and ERK2 cascade PDGFD;OPRM1;TLR4 8562:[DB01183 DB11275] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0045471| response to ethanol UGT1A1;DRD3;DRD2;OPRK1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0042060| wound healing OPRM1;DRD5 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD1;DRD5;DRD3 GO:0048148| behavioral response to cocaine DRD4;DRD1;DRD3;DRD2;OPRK1 GO:0007626| locomotory behavior DRD2;OPRK1;DRD3;DRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;DRD3;TLR4;DRD2;ESR1 GO:0048149| behavioral response to ethanol OPRM1;DRD4;DRD2 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;DRD5 GO:0042493| response to drug DRD3;CREB1;UGT1A1;DRD2;ABCB1;DRD1 GO:0043278| response to morphine OPRM1;DRD2;OPRK1;DRD3 GO:0008542| visual learning DRD3;CREB1;DRD2;DRD1 GO:0035094| response to nicotine CREB1;DRD2 GO:0042752| regulation of circadian rhythm CREB1;DRD4 GO:0042711| maternal behavior OPRK1;DRD1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007613| memory CREB1;DRD1 GO:0014002| astrocyte development TLR4;DRD1 GO:0007186| G-protein coupled receptor signaling pathway DRD1;DRD5;DRD4;OPRD1;OPRM1;OPRK1;DRD2;DRD3 GO:0007165| signal transduction DRD1;DRD5;ESR1;DRD4;OPRD1;OPRM1;OPRK1;DRD2;DRD3;TLR4;CREB1 GO:1900273| DRD2;CREB1 GO:0000187| activation of MAPK activity DRD4;TLR4 GO:0042220| response to cocaine DRD2;OPRK1;DRD3;DRD5;DRD1;OPRM1 GO:0008344| adult locomotory behavior DRD4;OPRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;DRD2 GO:0009636| response to toxin CES1;DRD2 GO:0007409| axonogenesis CREB1;DRD2 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;DRD1 GO:0048511| rhythmic process DRD4;CREB1 GO:0010628| positive regulation of gene expression TLR4;DRD1 GO:0001666| response to hypoxia DRD2;CREB1 8563:[DB01183 DB00650] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0055085| transmembrane transport ABCB1;SLC22A8;SLCO1A2 8564:[DB01183 DB04738] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04738|Motuporin PPP1CC common genes common pathways GO:0048511| rhythmic process CREB1;PPP1CC GO:0042752| regulation of circadian rhythm CREB1;PPP1CC 8565:[DB01183 DB01247] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01247|Isocarboxazid MAOA;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;MAOB;TLR4;OPRM1 GO:0045471| response to ethanol MAOB;UGT1A1;OPRK1;OPRM1 GO:0042493| response to drug MAOB;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process MAOB;CYP2C8;MAOA;CYP3A4 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0009636| response to toxin CES1;MAOB 8566:[DB01183 DB07542] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07542|5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOBUTYL-HEXANOIC ACID CTSD common genes common pathways 8567:[DB01183 DB05001] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05001|PSN9301 DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 8568:[DB01183 DB00111] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;FCGR2C;CREB1;FCGR2B;TLR4;IL2RB;OPRK1;FCGR1A GO:0002376| immune system process IL2RA;C1QC;C1QA;C1R;C1QB;TLR4;FCGR1A;FCGR2A GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB GO:1904646| TLR4;FCGR2B GO:0045087| innate immune response FCGR1A;C1R;C1QB;TLR4;C1QA;C1QC GO:0043066| negative regulation of apoptotic process ALB;IL2RB GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0016032| viral reproduction IL2RB;CREB1;FCGR2B GO:0006955| immune response C1QC;IL2RA;OPRD1;FCGR2C;FCGR3A;FCGR2B;FCGR3B;TLR4;C1R;OPRK1;FCGR1A GO:0006954| inflammatory response IL2RA;TLR4;FCGR2B GO:0009617| response to bacterium TLR4;FCGR2B 8569:[DB01183 DB06857] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06857|N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE PLAU common genes common pathways GO:0001666| response to hypoxia CREB1;PLAU GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;PLAU;CREB1;TLR4 8570:[DB01183 DB13933] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0007623| circadian rhythm F7;CREB1 GO:0002576| platelet degranulation ALB;F8 GO:0055114| oxidation-reduction process CYP2C8;F8;CYP3A4 GO:0006953| acute-phase response F8;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;F7 GO:0031100| organ regeneration F7;UGT1A1 GO:0014070| response to organic cyclic compound F7;UGT1A1 GO:0043627| response to estrogen stimulus F7;OPRK1;ESR1 GO:0001666| response to hypoxia F7;CREB1 8571:[DB01183 DB04796] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04796|Inecalcitol VDR common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;VDR GO:0010628| positive regulation of gene expression VDR;TLR4 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;VDR;CREB1;TLR4;OPRK1 GO:0007595| lactation VDR;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter VDR;ESR1 GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;VDR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;VDR GO:0006351| transcription, DNA-dependent CREB1;VDR;ESR1 GO:0043401| steroid hormone mediated signaling pathway VDR;ESR1 8572:[DB01183 DB13948] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0007610| behavior HTR2A;OPRK1 GO:0007165| signal transduction OPRD1;OPRM1;HTR2A;ESR1;OPRK1;TLR4;CREB1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRD1;OPRM1;OPRK1 GO:0007568| aging HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory CREB1;HTR2A GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;HTR2A;OPRM1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0019233| sensory perception of pain HTR2A;OPRD1;OPRM1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1;OPRK1 GO:0016032| viral reproduction CREB1;HTR2A GO:0042493| response to drug ABCB1;UGT1A1;CREB1;HTR2A GO:0007268| synaptic transmission HTR2A;OPRM1;OPRD1;OPRK1 8573:[DB01183 DB08574] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 8574:[DB01183 DB07768] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;AKR1C2;OPRD1;OPRM1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;AKR1C2;CYP3A4 GO:0030855| epithelial cell differentiation AKR1C2;AKR1C1;CES1 GO:0015721| bile acid and bile salt transport AKR1C1;SLCO1A2;ALB GO:0006805| xenobiotic metabolic process CES1;AKR1C1;CYP3A4;CYP2C8 GO:0007586| digestion AKR1C1;AKR1C2;UGT1A1 GO:0006629| lipid metabolic process AKR1C2;CYP3A4 GO:0055114| oxidation-reduction process AKR1C2;CYP2C8;AKR1C1;CYP3A4 8575:[DB01183 DB01053] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0015711| organic anion transport SLC22A6;SLCO1A2;SLC22A4;SLCO1B1;SLC22A5;SLC22A11 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLC22A6;SLCO4A1;SLC22A11;SLCO3A1;SLCO1A2;SLC22A8;SLCO1B1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1A2;ALB;SLCO2B1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport SLC22A11;SLCO4A1;SLC22A8;SLC15A2;SLC22A5;SLCO1B1;SLC22A4;SLCO1A2;SLCO3A1;SLCO2B1;ABCB1;SLC15A1;SLC22A6 GO:0006811| ion transport SLCO4A1;SLC22A11;SLC22A8;SLC22A5;SLC15A2;SLCO1B1;SLC22A4;SLCO1A2;SLCO3A1;SLCO2B1;SLC15A1 GO:0009636| response to toxin CES1;SLC22A8 GO:0007586| digestion UGT1A1;SLC15A1 8576:[DB01183 DB06830] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process GGPS1;CES1 8577:[DB01183 DB03247] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0007584| response to nutrient UGT1A1;POR GO:0001666| response to hypoxia CREB1;NOS1 GO:0014070| response to organic cyclic compound UGT1A1;DHODH GO:0032793| positive regulation of CREB transcription factor activity RPS6KA4;OPRD1 GO:0006468| protein phosphorylation SGK1;CREB1;RPS6KA4 GO:0042167| heme catabolic process UGT1A1;BLVRB GO:0071363| cellular response to growth factor stimulus CREB1;NOS1;OPRD1 GO:0007595| lactation DHODH;CREB1 GO:0006954| inflammatory response RPS6KA4;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity RPS6KA4;TLR4 GO:0055114| oxidation-reduction process BLVRB;NOS1;POR;CYP2C8;HAO1;CYP3A4;DPYD;DHODH;HAO2;PNPO GO:0045893| positive regulation of transcription, DNA-dependent ESR1;NOS1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;RPS6KA4 GO:0042493| response to drug DHODH;CREB1;UGT1A1;POR;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;NOS1;CYP2C8 GO:0042594| response to starvation DHODH;UGT1A1 GO:0042981| regulation of apoptotic process ESR1;CREB1;SGK1 GO:0043066| negative regulation of apoptotic process POR;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;POR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RPS6KA4;ESR1;CREB1;NOS1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;DHODH 8578:[DB01183 DB03907] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0051930| regulation of sensory perception of pain COMT;OPRK1;OPRD1;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;COMT GO:0043627| response to estrogen stimulus OPRK1;COMT;ESR1 GO:0032496| response to lipopolysaccharide OPRM1;COMT;UGT1A1;TLR4 GO:0042493| response to drug ABCB1;UGT1A1;COMT;CREB1 GO:0008210| estrogen metabolic process UGT1A1;COMT 8579:[DB01183 DB01085] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction CHRM1;ESR1;CHRM2;OPRM1;OPRD1;CREB1;TLR4;CHRM3;OPRK1;CHRM4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6;CYP2C8;UGT1A1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2A6;CYP2C8;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM2;CHRM1;CHRM4;OPRK1;CHRM3 GO:0042359| vitamin D metabolic process CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CES1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6;CYP2E1 GO:0007586| digestion CHRM3;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0042737| drug catabolic process CYP3A4 GO:0045471| response to ethanol CYP2E1;OPRM1;UGT1A1;OPRK1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CYP2E1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2A6;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2A6;CYP3A4;CYP2E1 GO:0008209| androgen metabolic process ESR1;CYP3A4 8580:[DB01183 DB06354] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;GRIK1 GO:0006811| ion transport SLCO1A2;GRIK1 GO:0006810| transport ABCB1;GRIK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;GABBR1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;GABBR1 GO:0007165| signal transduction ESR1;OPRM1;GABBR1;OPRD1;CREB1;TLR4;OPRK1 GO:0007268| synaptic transmission OPRM1;OPRD1;GRIK1;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIK1;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;GABBR1 8581:[DB01183 DB12773] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12773|Sifalimumab IFNA2 common genes common pathways GO:0045087| innate immune response IFNA2;TLR4 GO:0006954| inflammatory response IFNA2;TLR4 GO:0010629| negative regulation of gene expression ESR1;OPRD1;IFNA2;CREB1 GO:0051607| defense response to virus IFNA2;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;IFNA2 8582:[DB01183 DB04893] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04893|AZD3409 FNTB;FNTA common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FNTA 8583:[DB01183 DB07068] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07068|(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID PTPRB common genes common pathways 8584:[DB01183 DB04521] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04521|GSHNA GSTA3 common genes common pathways GO:0008152| metabolic process CES1;GSTA3;UGT1A1 8585:[DB01183 DB04756] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 8586:[DB01183 DB02018] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02018|Amido Phenyl Pyruvic Acid TPSB2 common genes common pathways 8587:[DB01183 DB11731] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;EGFR;TLR4 GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;EGFR GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;EGFR;OPRK1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;EGFR;TLR4 GO:0006468| protein phosphorylation CREB1;EGFR GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1;ESR1 GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0071363| cellular response to growth factor stimulus OPRD1;EGFR;CREB1 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1 GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;EGFR;CREB1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0001889| liver development UGT1A1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;EGFR GO:0007623| circadian rhythm EGFR;CREB1 GO:0042060| wound healing EGFR;OPRM1 8588:[DB01183 DB04753] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0006955| immune response OPRD1;PNP;TLR4;OPRK1 GO:0042493| response to drug UGT1A1;PNP;CREB1;ABCB1 8589:[DB01183 DB01033] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0007626| locomotory behavior OPRK1;HPRT1;OPRM1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0008152| metabolic process PPAT;CES1;UGT1A1 GO:1900745| XDH;OPRK1 GO:0007623| circadian rhythm CREB1;IMPDH2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;SLC29A1 GO:0007595| lactation XDH;SLC29A1;PPAT;CREB1 GO:0042493| response to drug PPAT;ABCC4;ABCB1;CREB1;UGT1A1 GO:0010629| negative regulation of gene expression CREB1;ESR1;XDH;OPRD1 GO:0055114| oxidation-reduction process ABCC4;XDH;CYP3A4;IMPDH2;CYP2C8;IMPDH1;AOX1 GO:0031100| organ regeneration UGT1A1;PPAT GO:0015711| organic anion transport SLCO1A2;ABCC5 GO:0017144| drug metabolic process AOX1;UGT1A1;CYP2C8;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLC22A8;SLCO1A2 GO:0071456| cellular response to hypoxia OPRD1;SLC29A1 GO:0006810| transport ABCC5;ABCB1 GO:0010033| response to organic substance CREB1;UGT1A1;ABCC4 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin CES1;SLC22A8 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0055085| transmembrane transport ABCC5;ABCB1;SLC22A8;SLCO1A2;ABCC4 8590:[DB01183 DB02264] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02264|O2-Sulfo-Glucuronic Acid FGF1;HGF;HS3ST3A1 common genes common pathways GO:0000187| activation of MAPK activity FGF1;TLR4;HGF GO:0032715| negative regulation of interleukin-6 production HGF;TLR4 GO:0035729| cellular response to hepatocyte growth factor stimulus HGF;CREB1 GO:0031100| organ regeneration HGF;UGT1A1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;FGF1;ESR1;OPRM1;OPRD1 GO:0030154| cell differentiation FGF1;CREB1 GO:0043066| negative regulation of apoptotic process HGF;ALB GO:0002576| platelet degranulation ALB;HGF GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;ESR1;HGF;CREB1;TLR4 GO:0032733| positive regulation of interleukin-10 production HGF;TLR4 GO:0001889| liver development HGF;UGT1A1 8591:[DB01183 DB05883] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05883|ABX-PTH PTH common genes common pathways GO:0042493| response to drug PTH;ABCB1;UGT1A1;CREB1 GO:0045471| response to ethanol OPRK1;UGT1A1;PTH;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PTH;CREB1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PTH GO:0007186| G-protein coupled receptor signaling pathway PTH;OPRD1;OPRM1;OPRK1 8592:[DB01183 DB08841] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08841|Tyramine SLC22A3 common genes common pathways GO:0015711| organic anion transport SLCO1A2;SLC22A3 GO:0006811| ion transport SLC22A3;SLCO1A2 GO:0055085| transmembrane transport ABCB1;SLC22A3;SLCO1A2 GO:0006855| drug transmembrane transport SLC22A3;ABCB1 8593:[DB01183 DB08814] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0001666| response to hypoxia NOS2;CREB1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006366| transcription from RNA polymerase II promoter ESR1;NFKB1;CREB1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| PTGS1;ALB GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;NFKB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;PDE10A;NFKB1;CREB1;TLR4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway PDE10A;OPRD1;OPRM1;OPRK1 GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;TLR4 GO:0006954| inflammatory response TLR4;PTGS1;NFKB1 GO:0010629| negative regulation of gene expression NOS2;CREB1;NFKB1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;NFKB1 GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;ESR1;CREB1 GO:0009617| response to bacterium TLR4;NOS2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C8;NOS2;PTGS1;CYP3A4 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0002576| platelet degranulation ALB GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;NOS2;NFKB1 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;ESR1;CREB1;TLR4 GO:0008152| metabolic process UGT1A1;CES1;PDE10A GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CES1;CYP3A4 GO:0043066| negative regulation of apoptotic process NFKB1;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NFKB1 GO:0045087| innate immune response TLR4;NFKB1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0071260| cellular response to mechanical stimulus TLR4;NFKB1 GO:0007623| circadian rhythm CREB1;NOS2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NFKB1 GO:0032496| response to lipopolysaccharide UGT1A1;NOS2;TLR4;OPRM1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006351| transcription, DNA-dependent CREB1;ESR1;NFKB1 8594:[DB01183 DB07443] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation DHODH;UGT1A1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;DHODH GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0007595| lactation DHODH;CREB1 8595:[DB01183 DB07032] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways GO:0007165| signal transduction ESR2;OPRK1;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TLR4;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 8596:[DB01183 DB07625] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07625|4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;PLAU;CREB1;TLR4 GO:0001666| response to hypoxia CREB1;PLAU 8597:[DB01183 DB00024] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00024|Thyrotropin alfa TSHR common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TSHR;TLR4;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway TSHR;OPRD1;OPRM1;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;TSHR 8598:[DB01183 DB05814] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05814|GPI-1485 FKBP1A;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070588| calcium ion transmembrane transport OPRM1;FKBP1A GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FKBP1A GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 8599:[DB01183 DB08844] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLCO1A2 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0055085| transmembrane transport SLC22A6;ABCB1;SLC2A9;SLC22A8;SLCO1A2 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0070266| necroptosis PYGL;TLR4 GO:0008152| metabolic process CES1;PYGL;UGT1A1 8600:[DB01183 DB01375] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01375|Aluminium monostearate TNNC1;VDAC1;VDAC2;VDAC3 common genes common pathways GO:0007268| synaptic transmission OPRD1;OPRM1;VDAC3;OPRK1;VDAC1 GO:0016032| viral reproduction CREB1;VDAC1 GO:0006811| ion transport VDAC3;VDAC2;SLCO1A2;VDAC1 GO:0055085| transmembrane transport ABCB1;VDAC1;SLCO1A2;VDAC3;VDAC2 GO:0030855| epithelial cell differentiation CES1;VDAC1 8601:[DB01183 DB07945] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07945|5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid FABP4 common genes common pathways GO:0050729| positive regulation of inflammatory response FABP4;TLR4 GO:0050727| regulation of inflammatory response ESR1;FABP4;TLR4 8602:[DB01183 DB09110] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09110|Coenzyme M GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GSR;CYP2C8 GO:0098869| GSR;ALB 8603:[DB01183 DB00810] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;CHRM1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;CHRM1;CHRNA2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CES1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0035094| response to nicotine CREB1;CHRNA2 8604:[DB01183 DB08382] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08382|Gosogliptin DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 8605:[DB01183 DB09460] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways GO:0043627| response to estrogen stimulus CA2;OPRK1;ESR1 GO:0010033| response to organic substance CREB1;UGT1A1;CA2 GO:0001666| response to hypoxia CREB1;CA9 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0042493| response to drug CA9;CREB1;UGT1A1;ABCB1 GO:0045672| positive regulation of osteoclast differentiation CREB1;CA2 8606:[DB01183 DB01405] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 8607:[DB01183 DB02613] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0006629| lipid metabolic process PNLIPRP2;CYP3A4 GO:0042594| response to starvation DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;DHODH GO:0007595| lactation DHODH;CREB1 GO:0014070| response to organic cyclic compound DHODH;UGT1A1 8608:[DB01183 DB05361] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;F2R;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;F2R GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;F2R GO:0043687| post-translational protein modification ALB;SERPINC1 GO:0045893| positive regulation of transcription, DNA-dependent F2R;ESR1;CREB1 GO:0007595| lactation CREB1;SERPINC1 GO:0006954| inflammatory response F2R;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;F2R;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;F2R GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;F2R;ESR1 GO:0044267| cellular protein metabolic process SERPINC1;ALB GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;F2R GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1;F2R GO:0008285| negative regulation of cell proliferation OPRM1;F2R GO:0007584| response to nutrient SERPINC1;UGT1A1 8609:[DB01183 DB08784] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 8610:[DB01183 DB02285] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02285|Protoporphyrin FTL common genes common pathways 8611:[DB01183 DB00038] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00038|Oprelvekin IL11RA common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;IL11RA;TLR4;CREB1;OPRK1 8612:[DB01183 DB06231] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06231|Caldaret SLC8A1 common genes common pathways GO:0042493| response to drug SLC8A1;ABCB1;UGT1A1;CREB1 GO:0051924| regulation of calcium ion transport SLC8A1;OPRD1 GO:0051481| reduction of cytosolic calcium ion concentration SLC8A1;OPRM1 GO:0055085| transmembrane transport ABCB1;SLC8A1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLC8A1 GO:0007584| response to nutrient UGT1A1;SLC8A1 GO:0001666| response to hypoxia CREB1;SLC8A1 GO:0071456| cellular response to hypoxia SLC8A1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration SLC8A1;OPRM1;ESR1 GO:0070588| calcium ion transmembrane transport OPRM1;SLC8A1 8613:[DB01183 DB00160] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0009636| response to toxin SLC7A8;CES1 GO:0006811| ion transport SLC36A1;SLCO1A2 GO:0042220| response to cocaine OPRM1;OPRK1;ABAT GO:0055085| transmembrane transport SLC36A1;SLC16A10;SLCO1A2;ABCB1;SLC1A4 GO:0001666| response to hypoxia ABAT;CREB1 GO:0051384| response to glucocorticoid stimulus AGXT;UGT1A1 GO:0006810| transport SLC7A8;ABCB1 GO:0007568| aging ABAT;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;AGXT2;OPRM1;ESR1 GO:0042493| response to drug CREB1;UGT1A1;ABAT;ABCB1 GO:0035094| response to nicotine ABAT;CREB1 GO:0045471| response to ethanol UGT1A1;OPRK1;ABAT;OPRM1 GO:0048148| behavioral response to cocaine OPRK1;ABAT GO:0007626| locomotory behavior OPRK1;ABAT;OPRM1 8614:[DB01183 DB00596] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0007165| signal transduction ESR1;OPRM1;NR3C1;OPRD1;OPRK1;CREB1;TLR4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 8615:[DB01183 DB07008] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0010629| negative regulation of gene expression CREB1;NOS2;ESR1;OPRD1 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0009617| response to bacterium TLR4;NOS2 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;NOS2;TLR4 GO:0007623| circadian rhythm CREB1;NOS2 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 8616:[DB01183 DB00094] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00094|Urofollitropin FSHR common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;FSHR;CREB1;TLR4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;FSHR;OPRK1 GO:0008584| male gonad development FSHR;ESR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;FSHR;TLR4 8617:[DB01183 DB00189] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006811| ion transport SLCO1A2;GABRB1;GABRG2;GABRQ;GABRE;GABRA1;GABRA6;GABRA4;GABRG3;GABRB3;GABRA5;GABRA3;GABRG1;GABRP;GABRB2;GABRD;GABRA2 GO:0009636| response to toxin CES1;GABRB1 GO:0007165| signal transduction GABRB3;GABRB1;OPRD1;GABRQ;OPRM1;GABRE;GABRA6;ESR1;OPRK1;GABRA5;GABRP;TLR4;GABRD;CREB1 GO:0006810| transport GABRA3;GABRA5;GABRD;GABRB2;ABCB1;GABRG2;GABRB1;GABRA1;GABRA6;GABRA4;GABRB3 GO:1901215| GABRB3;GABRB2;CREB1 GO:0042493| response to drug GABRG3;ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission OPRD1;GABRG2;OPRM1;GABRA5;GABRG1;GABRB2;GABRD;OPRK1 8618:[DB01183 DB11639] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways GO:0006366| transcription from RNA polymerase II promoter CREB1;BMPR2;ESR1 GO:0007179| transforming growth factor beta receptor signaling pathway BMPR1A;CREB1 GO:0021983| pituitary gland development BMPR1A;CREB1 GO:0006468| protein phosphorylation CREB1;BMPR2;BMPR1A GO:0030154| cell differentiation BMPR1A;CREB1 GO:0009267| cellular response to starvation BMPR2;ALB GO:0006955| immune response BMPR1A;OPRD1;TLR4;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;BMPR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;BMPR2;TLR4;BMPR1A;ESR1 8619:[DB01183 DB11075] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11075|Hypromellose EPCAM common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EPCAM;TLR4;CREB1;ESR1 GO:0048863| stem cell differentiation EPCAM;ESR1 8620:[DB01183 DB01366] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01366|Procaterol ADRB2 common genes common pathways GO:0016579| protein deubiquitination ESR1;ADRB2 GO:1904646| TLR4;ADRB2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;ADRB2;OPRM1;OPRD1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB2;OPRM1;OPRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 8621:[DB01183 DB00385] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00385|Valrubicin TOP2A common genes common pathways GO:0048511| rhythmic process CREB1;TOP2A GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;TOP2A;CREB1 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 8622:[DB01183 DB14596] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes CYP3A4 common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process PON1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;NR3C1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0009636| response to toxin CES1;PON1 GO:0002933| CYP2C8;CYP3A4 8623:[DB01183 DB01440] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006810| transport ABCB1;GABRB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;GABRB1 GO:0055085| transmembrane transport SLC16A3;ABCB1;SLCO1A2;SLC16A7;SLC16A1 GO:0009636| response to toxin GABRB1;CES1 GO:0006811| ion transport SLCO1A2;GABRB1 GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0032094| response to food SLC16A1;OPRM1 8624:[DB01183 DB04207] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04207|N-(5-Amino-5-Carboxypentyl)Glutamic Acid AASS common genes common pathways GO:0008152| metabolic process AASS;UGT1A1;CES1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;AASS 8625:[DB01183 DB13036] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13036|Ramatroban PTGDR2 common genes common pathways GO:0007218| neuropeptide signaling pathway OPRK1;OPRM1;OPRD1;PTGDR2 GO:0006955| immune response OPRD1;PTGDR2;TLR4;OPRK1 GO:0007268| synaptic transmission OPRD1;OPRM1;PTGDR2;OPRK1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;PTGDR2 GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;OPRM1;OPRD1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;PTGDR2;OPRD1;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGDR2;OPRD1;OPRM1 8626:[DB01183 DB01623] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2D6 GO:0019233| sensory perception of pain OPRD1;OPRM1;HTR2A;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6 GO:0045471| response to ethanol OPRK1;DRD2;UGT1A1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1;OPRK1 GO:0048148| behavioral response to cocaine HTR2A;DRD1;OPRK1;DRD2 GO:0043066| negative regulation of apoptotic process ALB GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;OPRM1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0007626| locomotory behavior OPRK1;DRD2;DRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD2 GO:0002576| platelet degranulation ALB GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug ABCB1;DRD2;UGT1A1;CREB1;DRD1;CYP1A2;HTR2A GO:0007268| synaptic transmission HTR2A;OPRD1;OPRM1;OPRK1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP1A2;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0016032| viral reproduction HTR2A;CREB1 GO:0042711| maternal behavior DRD1;OPRK1 GO:0035094| response to nicotine DRD2;CREB1 GO:0043278| response to morphine OPRK1;DRD2;OPRM1 GO:0008542| visual learning DRD2;CREB1;DRD1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;DRD1;HTR2A;OPRM1;OPRD1 GO:0051659| maintenance of mitochondrion location ALB GO:0014002| astrocyte development TLR4;DRD1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0043069| negative regulation of programmed cell death ALB GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007568| aging CREB1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1 GO:0007613| memory DRD1;HTR2A;CREB1 GO:0098869| ALB GO:1900273| DRD2;CREB1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0006898| receptor-mediated endocytosis ALB GO:0015711| organic anion transport SLC22A1;SLCO1A2 GO:0007165| signal transduction DRD2;OPRK1;CREB1;TLR4;DRD1;OPRM1;OPRD1;ESR1;HTR2A GO:0007610| behavior OPRK1;HTR2A GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;CYP2D6;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0009636| response to toxin CES1;DRD2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SLCO1A2;SLC22A1 GO:0007409| axonogenesis DRD2;CREB1 GO:0044267| cellular protein metabolic process ALB GO:0042220| response to cocaine OPRM1;DRD1;DRD2;OPRK1 GO:0001895| retina homeostasis ALB GO:0055085| transmembrane transport ABCB1;SLC22A1;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;TLR4;DRD2 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0010628| positive regulation of gene expression TLR4;DRD1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRM1;OPRD1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 8627:[DB01183 DB00033] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;IFNGR1 8628:[DB01183 DB08168] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways GO:0042981| regulation of apoptotic process CREB1;PPIF;ESR1 GO:0070266| necroptosis TLR4;PPIF GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;ESR1 GO:0043066| negative regulation of apoptotic process PPIF;ALB GO:0006351| transcription, DNA-dependent ESR1;HDAC8;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;HDAC8 GO:0010629| negative regulation of gene expression HDAC8;OPRD1;ESR1;CREB1 8629:[DB01183 DB13997] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes CYP3A4 common pathways GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0052695| cellular glucuronidation UGT1A3;UGT1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:1904224| UGT1A1;UGT1A3 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0008152| metabolic process UGT1A3;CES1;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A1 GO:0002933| CYP3A4;CYP2C8 GO:0045922| negative regulation of fatty acid metabolic process UGT1A3;UGT1A1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;ABCB5 GO:0036378| CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCB5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A3 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0030154| cell differentiation ABCB5;CREB1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A3;UGT1A1;CYP2C8 8630:[DB01183 DB01083] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes CYP3A4 common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process FASN;CYP2C8;LIPF;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process PLA2G4A;LIPF;FASN;CYP3A4;PNLIP GO:0008152| metabolic process CES1;FASN;PLA2G4A;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0030879| mammary gland development FASN;CREB1 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 8631:[DB01183 DB08044] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08044|ABT-341 DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8632:[DB01183 DB14582] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14582|Patisiran ALB;ORM1;ORM2 common genes ALB common pathways GO:0032720| negative regulation of tumor necrosis factor production TLR4;ORM1 GO:0006898| receptor-mediated endocytosis ALB GO:0032715| negative regulation of interleukin-6 production ORM1;TLR4 GO:0098869| ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB;ORM1;ORM2 GO:0043066| negative regulation of apoptotic process ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006954| inflammatory response ORM1;TLR4 GO:0006953| acute-phase response ORM2;ORM1;UGT1A1 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;ORM2;ORM1 GO:0043687| post-translational protein modification ALB 8633:[DB01183 DB00691] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 GO:0050727| regulation of inflammatory response ACE2;ESR1;TLR4 GO:0016032| viral reproduction ACE2;CREB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport SLCO1A2;SLC15A2;SLC15A1;ABCB1 GO:0006811| ion transport SLC15A1;SLC15A2;SLCO1A2 8634:[DB01183 DB02322] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways GO:0009636| response to toxin CES1;CCL5 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;CCL5 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;CCL5;OPRM1 GO:0043491| protein kinase B signaling cascade CCL5;CREB1 GO:0006955| immune response TLR4;OPRK1;OPRD1;CCL5 GO:0006954| inflammatory response CCL5;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway CCL5;TLR4 8635:[DB01183 DB05442] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;IL1B;OPRK1;CREB1;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process IL1B;TLR4;OPRM1;ESR1 GO:0032755| positive regulation of interleukin-6 production TLR4;IL1B GO:0032757| positive regulation of interleukin-8 production IL1B;TLR4 GO:0008285| negative regulation of cell proliferation IL1B;OPRM1 GO:0010628| positive regulation of gene expression TLR4;IL1B GO:0000187| activation of MAPK activity TLR4;IL1B GO:1900745| IL1B;OPRK1 GO:0071260| cellular response to mechanical stimulus TLR4;IL1B GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;IL1B GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;CREB1;TLR4;ESR1 GO:0046330| positive regulation of JNK cascade TLR4;IL1B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;IL1B GO:0032729| positive regulation of interferon-gamma production IL1B;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;ESR1 GO:0006955| immune response TLR4;OPRK1;IL1B;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IL1B GO:0006954| inflammatory response IL1B;TLR4 GO:0043491| protein kinase B signaling cascade IL1B;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;IL1B;ESR1 8636:[DB01183 DB09060] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0043627| response to estrogen stimulus ESR1;ABCC2;OPRK1 GO:0055085| transmembrane transport ABCB1;ABCC2;SLCO1A2;SLC22A8 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin CES1;SLC22A8 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0006810| transport ABCB1;ABCC2 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCC2 GO:0033762| response to glucagon stimulus ABCC2;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;ABCC2;OPRK1 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1;TLR4;OPRM1 8637:[DB01183 DB04733] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways GO:0002576| platelet degranulation ALB;ALDOA 8638:[DB01183 DB08594] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08594|TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 8639:[DB01183 DB04114] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways 8640:[DB01183 DB01599] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01599|Probucol ABCA1;CES1 common genes CES1 common pathways GO:0009636| response to toxin CES1 GO:0030855| epithelial cell differentiation CES1 GO:0055085| transmembrane transport ABCA1;SLCO1A2;ABCB1 GO:0007584| response to nutrient UGT1A1;ABCA1 GO:0008202| steroid metabolic process ABCA1;CYP3A4;UGT1A1;CYP2C8 GO:0045332| phospholipid translocation ABCA1;ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;ABCA1;OPRM1;OPRK1 GO:0090122| cholesterol ester hydrolysis involved in cholesterol transport CES1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;ABCA1 GO:0050702| interleukin-1 beta secretion ABCA1;TLR4 GO:0006695| cholesterol biosynthetic process CES1 GO:0008152| metabolic process CES1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0051791| medium-chain fatty acid metabolic process CES1 GO:0071222| cellular response to lipopolysaccharide ABCA1;OPRK1;TLR4 GO:0006629| lipid metabolic process ABCA1;CYP3A4 8641:[DB01183 DB12465] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12465|Ketanserin HTR2A common genes common pathways GO:0007610| behavior HTR2A;OPRK1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;HTR2A;ESR1 GO:0007568| aging CREB1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory CREB1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;HTR2A;OPRK1 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;TLR4 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2A;ESR1;OPRD1;OPRM1 GO:0016032| viral reproduction CREB1;HTR2A GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;HTR2A GO:0042493| response to drug ABCB1;CREB1;UGT1A1;HTR2A 8642:[DB01183 DB04559] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04559|N-(Chlorophenyl)-N'-Hydroxyguanidine NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS3 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 8643:[DB01183 DB09258] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways GO:0007595| lactation CREB1;SERPINC1 GO:0043687| post-translational protein modification ALB;SERPIND1;SERPINC1 GO:0007584| response to nutrient UGT1A1;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0044267| cellular protein metabolic process ALB;SERPINC1;SERPIND1 8644:[DB01183 DB02485] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 8645:[DB01183 DB09046] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09046|Metreleptin LEPR common genes common pathways GO:2000505| regulation of energy homeostasis OPRK1;LEPR 8646:[DB01183 DB04250] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04250|Butyrylthiocholine BCHE;BCHE common genes common pathways GO:0042493| response to drug ABCB1;CREB1;BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 8647:[DB01183 DB05936] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05936|CVT-6883 ADORA2B common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADORA2B;OPRK1;OPRD1;OPRM1 GO:0032722| positive regulation of chemokine production ADORA2B;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;ADORA2B;OPRK1;TLR4;CREB1 GO:0032755| positive regulation of interleukin-6 production ADORA2B;TLR4 GO:0044267| cellular protein metabolic process ALB;ADORA2B GO:0000187| activation of MAPK activity ADORA2B;TLR4 8648:[DB01183 DB08426] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08426|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE F10 common genes common pathways 8649:[DB01183 DB03305] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03305|N5-Iminoethyl-L-Ornithine NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process CYP3A4;NOS3;CYP2C8 8650:[DB01183 DB01736] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01736|[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium SLC25A4 common genes common pathways GO:0006810| transport ABCB1;SLC25A4 GO:0055085| transmembrane transport SLCO1A2;SLC25A4;ABCB1 GO:0016032| viral reproduction CREB1;SLC25A4 8651:[DB01183 DB03604] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03604|Tiratricol THRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;THRB;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;THRB GO:0060509| Type I pneumocyte differentiation CREB1;THRB GO:0043401| steroid hormone mediated signaling pathway THRB;ESR1 GO:0006351| transcription, DNA-dependent THRB;CREB1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;CREB1;TLR4;ESR1 8652:[DB01183 DB11755] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0045671| negative regulation of osteoclast differentiation TLR4;GPR55 GO:0055085| transmembrane transport TRPM8;ABCB1;TRPA1;TRPV2;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;GPR55;TLR4 GO:0042220| response to cocaine OPRK1;OPRM1;CNR1 GO:0006811| ion transport TRPV2;SLCO1A2;TRPM8;TRPA1 GO:0014070| response to organic cyclic compound UGT1A1;TRPA1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR2;CNR1 GO:0007584| response to nutrient UGT1A1;CNR1 GO:0010033| response to organic substance TRPA1;CREB1;UGT1A1 GO:0007613| memory CREB1;CNR1 GO:0007568| aging CNR1;CREB1 GO:0006810| transport TRPV2;ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;CNR2;OPRM1;CNR1;HTR1A;GPR55 GO:0007610| behavior HTR1A;OPRK1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;ESR1;GPR55;HTR1A;CNR1;OPRK1;CREB1;TLR4 GO:0050951| sensory perception of temperature stimulus TRPM8;OPRK1 GO:0070588| calcium ion transmembrane transport TRPA1;TRPM8;OPRM1;TRPV2 GO:0042493| response to drug UGT1A1;CREB1;TRPA1;ABCB1 GO:0043278| response to morphine CNR1;OPRM1;OPRK1 GO:0007600| sensory perception OPRM1;TRPV2;OPRK1 GO:0035094| response to nicotine CNR1;CREB1 GO:0006954| inflammatory response CNR2;TLR4 GO:0006955| immune response TLR4;OPRK1;CNR2;OPRD1 GO:0045471| response to ethanol OPRM1;CNR1;UGT1A1;OPRK1 GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR2;CNR1;TRPA1;OPRK1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;OPRM1;TLR4;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;CNR1 8653:[DB01183 DB01005] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0008152| metabolic process CES1;UGT1A1;RRM1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process RRM1;CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0008584| male gonad development ESR1;RRM1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 8654:[DB01183 DB04672] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways 8655:[DB01183 DB06140] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06140|SUVN-502 HTR6 common genes common pathways GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;HTR6 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;HTR6 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;HTR6;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;HTR6 8656:[DB01183 DB01057] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01057|Echothiophate BCHE;ALB common genes ALB common pathways GO:0042493| response to drug ABCB1;UGT1A1;BCHE;CREB1 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0043069| negative regulation of programmed cell death ALB 8657:[DB01183 DB01998] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways GO:0006953| acute-phase response UGT1A1;SERPINA1 GO:0043687| post-translational protein modification ALB;SERPINA1 GO:0002576| platelet degranulation ALB;SERPINA1 GO:0044267| cellular protein metabolic process SERPINA1;ALB 8658:[DB01183 DB13168] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0009267| cellular response to starvation FADS1;ALB GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0007568| aging CREB1;PTGS2 GO:0007613| memory PTGS2;CREB1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;PTGS2;ESR1 GO:0098869| ALB;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;TLR4;UGT1A1 GO:0019233| sensory perception of pain OPRK1;OPRM1;PTGS2;OPRD1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0050727| regulation of inflammatory response TLR4;ESR1;PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0006629| lipid metabolic process FADS1;FADS2;CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0042493| response to drug PTGS2;ABCB1;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent CREB1;FADS1;ESR1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;ALOX5;FADS1;FADS2;CYP2C8 GO:0006954| inflammatory response TLR4;PTGS2;ALOX5 8659:[DB01183 DB03066] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0032094| response to food SLC16A1;OPRM1 GO:0055085| transmembrane transport SLC16A7;SLCO1A2;SLC16A1;SLC16A3;ABCB1 8660:[DB01183 DB11892] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0042493| response to drug CYP1A2;ABCB1;CREB1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 8661:[DB01183 DB06756] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0051607| defense response to virus OPRK1;BCL2 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;BCHE;BCL2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PRODH GO:0035094| response to nicotine BCL2;CREB1 GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0043066| negative regulation of apoptotic process ALB;BCL2 GO:0009314| response to radiation OPRK1;OPRM1;BCL2 GO:0042981| regulation of apoptotic process CREB1;ESR1;BCL2 GO:0009636| response to toxin BCL2;CES1 GO:0007409| axonogenesis BCL2;CREB1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;BCL2 GO:0055085| transmembrane transport ABCB1;SLCO1A2;BCL2 GO:0030890| positive regulation of B cell proliferation BCL2;TLR4 GO:0008584| male gonad development ESR1;BCL2 GO:0008285| negative regulation of cell proliferation OPRM1;BCL2;BCHE GO:0007584| response to nutrient BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus BCL2;BCHE;UGT1A1 GO:0040018| positive regulation of multicellular organism growth BCL2;CREB1 GO:0071456| cellular response to hypoxia OPRD1;BCL2 GO:0048545| response to steroid hormone stimulus UGT1A1;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BCL2 8662:[DB01183 DB07389] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0009617| response to bacterium TLR4;NOS2 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;NOS2 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;NOS2;TLR4 GO:0007623| circadian rhythm CREB1;NOS2 GO:0001666| response to hypoxia CREB1;NOS2 8663:[DB01183 DB03073] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03073|3-Methoxybenzamide PARP1 common genes common pathways GO:1904646| PARP1;TLR4 GO:0006366| transcription from RNA polymerase II promoter ESR1;PARP1;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;PARP1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0071294| cellular response to zinc ion PARP1;CREB1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;PARP1 8664:[DB01183 DB03009] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03009|2-[(2-Oxo-2-Piperidin-1-Ylethyl)Thio]-6-(Trifluoromethyl)Pyrimidin-4(1h)-One FABP4 common genes common pathways GO:0050727| regulation of inflammatory response FABP4;ESR1;TLR4 GO:0050729| positive regulation of inflammatory response TLR4;FABP4 8665:[DB01183 DB09332] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0032355| response to estradiol stimulus F7;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;F2 GO:0017144| drug metabolic process CYP3A4;VKORC1;CYP2C8;UGT1A1 GO:0031100| organ regeneration F7;UGT1A1 GO:0044267| cellular protein metabolic process ALB;F2;PROC GO:0014070| response to organic cyclic compound UGT1A1;F7 GO:0043627| response to estrogen stimulus OPRK1;F7;ESR1 GO:0007584| response to nutrient POR;UGT1A1 GO:0001666| response to hypoxia CREB1;F7 GO:0001889| liver development PROC;UGT1A1 GO:0007623| circadian rhythm CREB1;F7 GO:0006805| xenobiotic metabolic process CYP2C8;POR;CYP3A4;CES1 GO:0043066| negative regulation of apoptotic process POR;ALB;PROC GO:0002576| platelet degranulation PROS1;ALB GO:0055114| oxidation-reduction process CYP2C8;POR;CYP3A4;VKORC1 GO:0043687| post-translational protein modification PROC;ALB GO:0042493| response to drug UGT1A1;CREB1;POR;ABCB1 GO:0006953| acute-phase response F2;UGT1A1 8666:[DB01183 DB01750] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01750|1-naphthaleneacetic acid SKP1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle SKP1;ABCB1 GO:0043687| post-translational protein modification SKP1;ALB 8667:[DB01183 DB02596] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02596|Alpha,Beta-Methyleneadenosine-5'-Triphosphate folK;panC;nadE;NMNAT3;carA common genes common pathways 8668:[DB01183 DB00029] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0002376| immune system process TLR4;FGA GO:0032757| positive regulation of interleukin-8 production SERPINE1;TLR4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;PLAUR;FGA;ESR1;OPRD1;OPRM1 GO:0050729| positive regulation of inflammatory response SERPINE1;TLR4 GO:0002224| toll-like receptor signaling pathway FGA;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;PLG GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;FGA GO:0044267| cellular protein metabolic process FGA;ALB;PLG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;SERPINE1;ESR1 GO:0050829| defense response to Gram-negative bacterium SERPINE1;TLR4 GO:0071222| cellular response to lipopolysaccharide SERPINE1;TLR4;OPRK1 GO:0002576| platelet degranulation ALB;FGA;PLG;SERPINE1 GO:0043066| negative regulation of apoptotic process ALB;PLAUR GO:0045087| innate immune response FGA;TLR4 GO:0007623| circadian rhythm CREB1;SERPINE1 GO:0043687| post-translational protein modification FGA;ALB 8669:[DB01183 DB08051] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8670:[DB01183 DB08127] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways GO:0042573| retinoic acid metabolic process CRABP2;UGT1A1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;CRABP2;OPRD1;OPRM1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CRABP2;ESR1;CREB1 8671:[DB01183 DB03023] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;LYN GO:0043066| negative regulation of apoptotic process ALB;SRC GO:0071560| cellular response to transforming growth factor beta stimulus SRC;CREB1 GO:0060065| uterus development SRC;ESR1 GO:0071398| cellular response to fatty acid CREB1;SRC GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0071222| cellular response to lipopolysaccharide SRC;OPRK1;TLR4 GO:0002576| platelet degranulation LYN;ALB GO:0043065| positive regulation of apoptotic process CREB1;SRC GO:0050727| regulation of inflammatory response LYN;TLR4;ESR1 GO:0045087| innate immune response SRC;LCK;LYN;TLR4 GO:0016032| viral reproduction CREB1;LYN;LCK;SRC GO:0050707| regulation of cytokine secretion LYN;TLR4 GO:0006954| inflammatory response LYN;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;SRC;ESR1 GO:0042493| response to drug SRC;UGT1A1;LYN;CREB1;LCK;ABCB1 GO:0002376| immune system process SRC;LYN;TLR4 GO:0007165| signal transduction SRC;OPRD1;OPRM1;ESR1;OPRK1;LYN;TLR4;CREB1 GO:0036120| SRC;CREB1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0006468| protein phosphorylation SRC;CREB1;LYN;LCK GO:0010628| positive regulation of gene expression SRC;TLR4 GO:0033146| regulation of intracellular estrogen receptor signaling pathway SRC;ESR1 GO:0008285| negative regulation of cell proliferation LYN;OPRM1 GO:0007411| axon guidance SRC;CREB1 GO:0009636| response to toxin LYN;CES1 GO:0014070| response to organic cyclic compound UGT1A1;LYN GO:0070373| negative regulation of ERK1 and ERK2 cascade LYN;TLR4 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;SRC;TLR4 GO:0032868| response to insulin stimulus OPRK1;LYN 8672:[DB01183 DB11779] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11779|Danoprevir CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 8673:[DB01183 DB00550] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0002933| CYP3A4;CYP2C8;CYP1A1 GO:0009636| response to toxin CES1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0017144| drug metabolic process CYP1A1;UGT1A1;CYP2C8;CYP3A4 GO:0097267| CYP2C8;CYP1A1 GO:0098869| TPO;ALB GO:0007613| memory DBH;CREB1 GO:0007568| aging CREB1;CYP1A1;MPO GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP1A1;CYP2C8 GO:0008542| visual learning DBH;CREB1 GO:0042711| maternal behavior OPRK1;DBH GO:0055114| oxidation-reduction process CYP3A4;MPO;DBH;CYP1A1;TPO;CYP2C8 GO:0042742| defense response to bacterium TLR4;MPO GO:0007268| synaptic transmission OPRM1;OPRD1;DBH;OPRK1 GO:0042493| response to drug CYP1A1;CREB1;UGT1A1;ABCB1 GO:0032094| response to food OPRM1;MPO;CYP1A1 GO:0048149| behavioral response to ethanol DBH;OPRM1 GO:0007626| locomotory behavior DBH;OPRM1;OPRK1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0043066| negative regulation of apoptotic process MPO;ALB GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A1;MPO;OPRM1 8674:[DB01183 DB06419] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06419|Cethromycin CYP3A5;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0002933| CYP3A4;CYP3A5;CYP2C8 GO:0036378| CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP3A5 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP3A5;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 8675:[DB01183 DB07274] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07274|N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide KDR common genes common pathways GO:0030154| cell differentiation KDR;CREB1 GO:0006468| protein phosphorylation KDR;CREB1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR GO:0043066| negative regulation of apoptotic process ALB;KDR GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;KDR GO:0016032| viral reproduction CREB1;KDR 8676:[DB01183 DB03344] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03344|Inositol-(1,3,4,5,6)-Pentakisphosphate CYTH3 common genes common pathways 8677:[DB01183 DB05130] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05130|INCB3284 CCR2 common genes common pathways GO:0050729| positive regulation of inflammatory response CCR2;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;CCR2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;CCR2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;CCR2;ESR1;OPRM1;OPRD1 GO:0006955| immune response CCR2;OPRD1;OPRK1;TLR4 GO:0016032| viral reproduction CCR2;CREB1 GO:0006954| inflammatory response CCR2;TLR4 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process TLR4;CCR2 GO:0032729| positive regulation of interferon-gamma production CCR2;TLR4 GO:0007194| negative regulation of adenylate cyclase activity CCR2;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;CCR2 8678:[DB01183 DB07060] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07060|3-(INDOL-3-YL) LACTATE HAO1 common genes common pathways GO:0055114| oxidation-reduction process HAO1;CYP3A4;CYP2C8 8679:[DB01183 DB09052] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09052|Blinatumomab CD19;CD3D common genes common pathways GO:0002376| immune system process TLR4;CD3D GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CD3D;CREB1 8680:[DB01183 DB08834] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes SLCO1A2 common pathways GO:0009636| response to toxin CES1;SLC7A11 GO:0006811| ion transport SLCO1A2 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0015711| organic anion transport SLCO1A2 GO:0035094| response to nicotine SLC7A11;CREB1 8681:[DB01183 DB07843] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07843|5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways 8682:[DB01183 DB03153] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways GO:0007626| locomotory behavior HPRT1;OPRK1;OPRM1 8683:[DB01183 DB12651] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12651|Bardoxolone CASP8 common genes common pathways GO:0035666| TRIF-dependent toll-like receptor signaling pathway CASP8;TLR4 GO:0032355| response to estradiol stimulus CASP8;ESR1 GO:0016032| viral reproduction CREB1;CASP8 GO:0042981| regulation of apoptotic process ESR1;CASP8;CREB1 GO:0071260| cellular response to mechanical stimulus CASP8;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;CASP8;TLR4;UGT1A1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;CASP8 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CASP8 GO:0097190| apoptotic signaling pathway CASP8;TLR4 GO:0045471| response to ethanol OPRK1;CASP8;UGT1A1;OPRM1 8684:[DB01183 DB00298] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00298|Dapiprazole ADRA1A;ADRA1D;ADRA1B common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;ADRA1B;ADRA1D;ADRA1A;OPRK1 GO:0042493| response to drug ABCB1;ADRA1A;CREB1;UGT1A1 GO:0007165| signal transduction CREB1;TLR4;ADRA1D;OPRK1;ADRA1A;ESR1;OPRM1;OPRD1;ADRA1B GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;OPRM1;OPRD1;OPRK1;ADRA1A;ADRA1D GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1D;ADRA1B;OPRM1;ESR1 GO:0007568| aging ADRA1A;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ADRA1A;TLR4 8685:[DB01183 DB12489] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 8686:[DB01183 DB00145] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0007218| neuropeptide signaling pathway GLRB;OPRK1;GLRA1;GLRA2;OPRM1;OPRD1;GLRA3 GO:0043065| positive regulation of apoptotic process CREB1;GRIN2A GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;GLYAT GO:0008152| metabolic process UGT1A1;GCAT;ALAS2;CES1;ALAS1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1;GLRA2 GO:0006629| lipid metabolic process CYP3A4;BAAT GO:0071294| cellular response to zinc ion GLRA1;CREB1;GLRA2 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2C;GLRA1;GLRB;GRIN3B;OPRM1;GLRA3;GRIN2A;GLRA2 GO:0045471| response to ethanol OPRK1;UGT1A1;GRIN2A;OPRM1 GO:0001889| liver development UGT1A1;BAAT GO:0019233| sensory perception of pain OPRK1;GRIN2A;OPRD1;OPRM1 GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:0008542| visual learning GRIN2A;CREB1 GO:0042493| response to drug GRIN2A;UGT1A1;CREB1;ABCB1 GO:0007268| synaptic transmission GLRA3;OPRM1;OPRD1;GLRA2;GRIN2A;SLC6A5;GLRA1;OPRK1;GLRB GO:0055114| oxidation-reduction process CYP3A4;GLDC;PIPOX;CYP2C8 GO:0070588| calcium ion transmembrane transport OPRM1;GRIN3B GO:0031100| organ regeneration BAAT;UGT1A1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GPR18 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;AGXT2;TLR4 GO:1900273| GRIN2A;CREB1 GO:0007165| signal transduction GPR18;TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;GPR18;OPRK1 GO:0051384| response to glucocorticoid stimulus AGXT;UGT1A1 GO:0007613| memory GRIN2A;CREB1 GO:0006810| transport SLC6A9;SLC6A5;GRIN2A;GRIN2C;ABCB1 GO:0007568| aging GSS;SLC32A1;CREB1 GO:1990830| GLDC;CREB1;SHMT1 GO:1904646| GRIN2A;TLR4 GO:0001666| response to hypoxia ALAS2;CREB1 GO:0006811| ion transport SLCO1A2;GLRA3;SLC36A1;GRIN2A;GLRA2;GRIN2C;GLRA1;GLRB;GRIN3B;SLC32A1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;GRIN2A;OPRK1 GO:0009636| response to toxin CES1;GLYAT GO:0055085| transmembrane transport SLC36A1;SLC6A9;SLC6A5;SLC16A10;SLCO1A2;ABCB1 8687:[DB01183 DB08892] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A1;SLCO1A2 GO:0007165| signal transduction ESR1;OPRM1;GABBR1;OPRD1;GABBR2;OPRK1;CREB1;TLR4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;GABBR1;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;GABBR1;OPRD1;GABBR2;OPRK1 GO:0032094| response to food SLC16A1;OPRM1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;GABBR2 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0007194| negative regulation of adenylate cyclase activity GABBR2;OPRM1;GABBR1 8688:[DB01183 DB04410] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways GO:0007586| digestion PRSS1;PRSS2;UGT1A1 8689:[DB01183 DB00830] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0045471| response to ethanol OPRM1;UGT1A1;SLC6A3;OPRK1 GO:0007626| locomotory behavior OPRK1;SLC6A3;OPRM1 GO:0042493| response to drug ABCB1;SLC6A3;UGT1A1;SLC6A2;CREB1 GO:0007268| synaptic transmission OPRK1;SLC6A2;OPRD1;OPRM1 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007595| lactation SLC6A3;CREB1 GO:0007568| aging CREB1;SLC6A3 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0006810| transport SLC6A2;ABCB1 GO:0042220| response to cocaine SLC6A3;OPRK1;OPRM1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC6A3;SLC6A2 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 8690:[DB01183 DB11805] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11805|Saracatinib CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 8691:[DB01183 DB14017] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14017|H3B-8800 SF3B1 common genes common pathways 8692:[DB01183 DB06346] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06346|Fiboflapon ALOX5AP common genes common pathways 8693:[DB01183 DB00888] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00888|Mechlorethamine BCHE common genes common pathways GO:0042493| response to drug UGT1A1;BCHE;CREB1;ABCB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE 8694:[DB01183 DB03918] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03918|6S-5,6,7,8-Tetrahydrobiopterin NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 8695:[DB01183 DB00052] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00052|Somatotropin GHR;PRLR common genes common pathways GO:0040018| positive regulation of multicellular organism growth CREB1;GHR GO:0032355| response to estradiol stimulus GHR;ESR1 GO:0032870| cellular response to hormone stimulus GHR;UGT1A1 GO:0000187| activation of MAPK activity GHR;TLR4 GO:0060749| mammary gland alveolus development PRLR;ESR1 GO:0043066| negative regulation of apoptotic process ALB;PRLR GO:0007595| lactation CREB1;PRLR 8696:[DB01183 DB05967] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05967|ANZ-100 KISS1R common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;KISS1R GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;KISS1R;OPRK1 GO:0007218| neuropeptide signaling pathway KISS1R;OPRM1;OPRD1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1;KISS1R 8697:[DB01183 DB12243] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1;SLC22A8;SLCO1A2 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB;SLC22A6 8698:[DB01183 DB05448] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05448|PX-12 TXNRD1 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;TXNRD1 GO:0098869| TXNRD1;ALB GO:0055114| oxidation-reduction process TXNRD1;CYP3A4;CYP2C8 8699:[DB01183 DB07151] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07151|4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one PIM1 common genes common pathways GO:0006468| protein phosphorylation PIM1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;ALB 8700:[DB01183 DB04282] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04282|2-deoxy-2-fluoro-α-D-glucose LCT common genes common pathways GO:0008152| metabolic process UGT1A1;LCT;CES1 8701:[DB01183 DB11830] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways GO:0006338| chromatin remodeling HDAC1;ESR1;HDAC2 GO:0032732| positive regulation of interleukin-1 production HDAC2;TLR4;HDAC1 GO:0042220| response to cocaine OPRM1;HDAC2;OPRK1 GO:0048511| rhythmic process CREB1;HDAC1;HDAC2 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC2 GO:0008285| negative regulation of cell proliferation HDAC1;OPRM1 GO:0006351| transcription, DNA-dependent ESR1;HDAC3;HDAC2;HDAC1;CREB1 GO:0007623| circadian rhythm HDAC3;CREB1 GO:0032496| response to lipopolysaccharide HDAC2;OPRM1;UGT1A1;HDAC1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;HDAC3;HDAC2;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;HDAC1;CREB1;HDAC3;HDAC2;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus HDAC2;CREB1 GO:0043066| negative regulation of apoptotic process ALB;HDAC1;HDAC3;HDAC2 GO:0042493| response to drug HDAC2;ABCB1;UGT1A1;HDAC1;CREB1 GO:0010629| negative regulation of gene expression CREB1;HDAC1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HDAC1;ESR1;HDAC2;HDAC3 GO:0048149| behavioral response to ethanol HDAC2;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;HDAC2;CREB1;HDAC1 GO:0032760| positive regulation of tumor necrosis factor production HDAC1;TLR4;HDAC2 GO:0035094| response to nicotine CREB1;HDAC2 GO:0016032| viral reproduction CREB1;HDAC1 8702:[DB01183 DB02080] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02080|1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene PLA2G2A;lepB;TTPA common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PLA2G2A GO:0009636| response to toxin CES1;TTPA GO:0007584| response to nutrient UGT1A1;TTPA GO:0006810| transport ABCB1;TTPA GO:0050729| positive regulation of inflammatory response TLR4;PLA2G2A GO:0006629| lipid metabolic process PLA2G2A;TTPA;CYP3A4 8703:[DB01183 DB05532] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05532|BMS-488043 FFAR4 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade FFAR4;OPRM1;TLR4 GO:0007165| signal transduction OPRD1;FFAR4;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0032870| cellular response to hormone stimulus FFAR4;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;FFAR4;OPRM1;OPRK1 GO:0043066| negative regulation of apoptotic process FFAR4;ALB 8704:[DB01183 DB05449] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05449|FM-VP4 ABCB1 common genes ABCB1 common pathways GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 8705:[DB01183 DB07180] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways GO:0006468| protein phosphorylation CREB1;NEK2 GO:0000086| G2/M transition of mitotic cell cycle NEK2;ABCB1 8706:[DB01183 DB09348] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09348|Propiolactone ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB 8707:[DB01183 DB14001] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14001|alpha-Tocopherol succinate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0006468| protein phosphorylation PRKCB;CREB1;PRKCA GO:0071456| cellular response to hypoxia OPRD1;HMOX1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0007568| aging CREB1;NQO1;SOD1;GCLC GO:0006810| transport TTPA;ABCB1 GO:0032355| response to estradiol stimulus NQO1;GSTP1;ESR1 GO:0008202| steroid metabolic process CYP3A4;NR1I2;UGT1A1;CYP2C8 GO:0042167| heme catabolic process UGT1A1;HMOX1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;PRKCB;CREB1;TLR4;NR1I2;OPRK1 GO:0002376| immune system process TLR4;PRKCB GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0098869| GSTP1;ALB;GSTO1 GO:0030111| regulation of Wnt receptor signaling pathway PPP2CA;ESR1 GO:0035729| cellular response to hepatocyte growth factor stimulus GCLC;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PRKCA GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0030855| epithelial cell differentiation GSTA2;CES1 GO:0000187| activation of MAPK activity TLR4;SOD1 GO:0001895| retina homeostasis SOD1;ALB GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0014070| response to organic cyclic compound UGT1A1;NQO1 GO:0009636| response to toxin CES1;NQO1;TTPA;GSTP1 GO:0043627| response to estrogen stimulus OPRK1;GSTM3;ESR1;HMOX1 GO:0007411| axon guidance PRKCA;CREB1 GO:0007584| response to nutrient GCLC;UGT1A1;TTPA;NQO1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity HMOX1;ESR1 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0010033| response to organic substance SOD1;UGT1A1;CREB1;PPP2CA GO:0014823| response to activity CREB1;GCLC GO:0010628| positive regulation of gene expression TLR4;NR1I2 GO:0001666| response to hypoxia CREB1;HMOX1;PRKCB GO:0045471| response to ethanol OPRM1;SOD1;GSTP1;OPRK1;UGT1A1;NQO1 GO:0097190| apoptotic signaling pathway PRKCA;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;PRKCB;TLR4 GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0006351| transcription, DNA-dependent PRKCB;SEC14L2;ESR1;NR1I2;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PRKCB GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;GSTP1 GO:0006629| lipid metabolic process CYP3A4;TTPA GO:0071260| cellular response to mechanical stimulus GCLC;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;SOD1;HMOX1 GO:0002576| platelet degranulation SOD1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;NR1I2;CREB1 GO:0007626| locomotory behavior OPRK1;OPRM1;SOD1 GO:0071222| cellular response to lipopolysaccharide GSTP1;OPRK1;TLR4 GO:0008152| metabolic process GSTP1;UGT1A1;GSTM3;DGKA;GSTA2;CES1;GSTO1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;NQO1;NR1I2;CYP2C8;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB;NQO1;GCLC;SOD1 GO:0055114| oxidation-reduction process ALOX5;CYP3A4;GSTO1;HMOX1;SOD1;CYP2C8;NQO1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;SOD1 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR1I2;PPP2CA;ESR1;PRKCB;SEC14L2 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;SEC14L2;CREB1;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0035094| response to nicotine HMOX1;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;PRKCB GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0006954| inflammatory response ALOX5;TLR4 8708:[DB01183 DB04988] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04988|IGN311 EGFR;ERBB2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ERBB2;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;EGFR;ESR1 GO:0071260| cellular response to mechanical stimulus TLR4;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;EGFR;CREB1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0001889| liver development UGT1A1;EGFR GO:0006351| transcription, DNA-dependent ERBB2;ESR1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1;ERBB2 GO:0007623| circadian rhythm EGFR;CREB1 GO:0042060| wound healing EGFR;OPRM1;ERBB2 GO:0048146| positive regulation of fibroblast proliferation ESR1;EGFR GO:0010628| positive regulation of gene expression ERBB2;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade EGFR;TLR4;OPRM1 GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0007165| signal transduction TLR4;CREB1;EGFR;OPRK1;OPRD1;OPRM1;ESR1;ERBB2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;EGFR GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0006468| protein phosphorylation CREB1;EGFR;ERBB2 GO:0071363| cellular response to growth factor stimulus ERBB2;OPRD1;EGFR;CREB1 GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0050729| positive regulation of inflammatory response TLR4;EGFR 8709:[DB01183 DB08058] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 8710:[DB01183 DB07739] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07739|(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE PNMT common genes common pathways 8711:[DB01183 DB09539] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SOAT1 GO:0008202| steroid metabolic process CYP3A4;SOAT1;UGT1A1;CYP2C8 8712:[DB01183 DB03953] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03953|L-Thiocitrulline NOS2 common genes common pathways GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0071222| cellular response to lipopolysaccharide TLR4;NOS2;OPRK1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide UGT1A1;NOS2;TLR4;OPRM1 GO:0010629| negative regulation of gene expression NOS2;CREB1;OPRD1;ESR1 GO:0009617| response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0001666| response to hypoxia NOS2;CREB1 8713:[DB01183 DB02933] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 8714:[DB01183 DB02056] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway PTGDR2;OPRD1;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;OPRM1;AKR1C3;OPRD1;OPRK1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;AKR1C3;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO2A1;ALB GO:0009267| cellular response to starvation AKR1C3;ALB GO:0007165| signal transduction OPRK1;CREB1;TLR4;PTGDR2;ESR1;OPRM1;OPRD1 GO:0055085| transmembrane transport ABCB1;SLCO2A1;SLCO1A2 GO:0007584| response to nutrient AKR1C3;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;PTGDR2 GO:0008584| male gonad development AKR1C3;ESR1 GO:0000060| protein import into nucleus, translocation OPRD1;AKR1C3 GO:0007218| neuropeptide signaling pathway OPRK1;PTGDR2;OPRM1;OPRD1 GO:0055114| oxidation-reduction process AKR1C3;CYP3A4;CYP2C8 GO:0007268| synaptic transmission PTGDR2;OPRD1;OPRM1;OPRK1 GO:0006955| immune response PTGDR2;OPRD1;OPRK1;TLR4 8715:[DB01183 DB01294] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01294|Bismuth Subsalicylate ALB;TF common genes ALB common pathways GO:0043687| post-translational protein modification ALB;TF GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation TF;ALB GO:0044267| cellular protein metabolic process TF;ALB GO:0001895| retina homeostasis ALB;TF GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport TF;SLCO1A2 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0043069| negative regulation of programmed cell death ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB 8716:[DB01183 DB04665] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04665|Coumarin CYP2A6;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2C8;UGT1A1;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C9;UGT1A1;CYP2C8;CYP2A6;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2A6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4;CYP2A6 8717:[DB01183 DB06643] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06643|Denosumab TNFSF11 common genes common pathways GO:0030154| cell differentiation CREB1;TNFSF11 GO:1990830| CREB1;TNFSF11 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0046330| positive regulation of JNK cascade TLR4;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNFSF11 GO:0006955| immune response OPRK1;TLR4;TNFSF11;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TLR4 8718:[DB01183 DB04723] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways 8719:[DB01183 DB00105] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00105|Interferon Alfa-2b, Recombinant IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2;IFNAR1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0051607| defense response to virus IFNAR2;OPRK1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 8720:[DB01183 DB04821] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0042220| response to cocaine OPRM1;SLC6A3;OPRK1 GO:0055085| transmembrane transport SLC18A2;SLCO1A2;SLC6A4;SLC6A2;SLC6A3;ABCB1 GO:0009636| response to toxin SLC18A2;CES1;SLC6A4;MAOB GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0010033| response to organic substance SLC6A4;CREB1;UGT1A1 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0001666| response to hypoxia CREB1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging SLC6A3;CREB1;MPO GO:0007613| memory CREB1;SLC6A4 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0032715| negative regulation of interleukin-6 production ORM1;TLR4 GO:0032720| negative regulation of tumor necrosis factor production TLR4;ORM1 GO:0042742| defense response to bacterium TLR4;MPO GO:0055114| oxidation-reduction process MPO;MAOA;CYP3A4;CYP2C8;MAOB GO:0032094| response to food MPO;OPRM1 GO:0007268| synaptic transmission SLC18A2;OPRM1;OPRD1;SLC6A2;OPRK1 GO:0042493| response to drug SLC6A2;UGT1A1;MAOB;CREB1;ABCB1;SLC6A3;SLC6A4 GO:0035094| response to nicotine SLC6A3;CREB1 GO:0050718| positive regulation of interleukin-1 beta secretion ORM1;TLR4 GO:0007595| lactation SLC6A3;CREB1 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0006954| inflammatory response ORM1;TLR4 GO:0045471| response to ethanol OPRK1;SLC6A3;UGT1A1;MAOB;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;MPO;MAOB;UGT1A1;TLR4 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0007626| locomotory behavior OPRK1;SLC6A3;SLC18A2;OPRM1 GO:0002576| platelet degranulation ALB;ORM1 8721:[DB01183 DB04653] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04653|CBZ-LEU-LEU-TYR-CH2F CAPN1 common genes common pathways 8722:[DB01183 DB02565] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;HDAC8 GO:0006351| transcription, DNA-dependent ESR1;HDAC8;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;HDAC8;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HDAC8;ESR1 8723:[DB01183 DB03166] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1A2 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1A2 GO:0055085| transmembrane transport SLCO2B1;ABCB1;SLC16A1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLCO2B1 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0032094| response to food OPRM1;SLC16A1 8724:[DB01183 DB07616] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HPGDS GO:0007626| locomotory behavior OPRK1;HPGDS;OPRM1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;HPGDS;OPRD1;OPRM1;ESR1 8725:[DB01183 DB07136] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 8726:[DB01183 DB04576] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0048511| rhythmic process CREB1;TOP2A GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TOP2A;CREB1;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 8727:[DB01183 DB02337] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 8728:[DB01183 DB14641] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes SLCO1A2;ABCB1;ESR1 common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0006811| ion transport SLCO1A2 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;ESR2;OPRK1 GO:0015711| organic anion transport SLCO1A2 GO:0002064| epithelial cell development ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR2;UGT1A1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;CREB1;TLR4 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:1901529| ABCB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 8729:[DB01183 DB00116] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;ABCC2;UGT1A1;TLR4 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0008152| metabolic process CES1;MTHFR;FTCD;ALDH1L1;ATIC;MTHFD2;MTHFD1;UGT1A1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ABCC2 GO:0055114| oxidation-reduction process MTHFR;CYP3A4;MTHFD2;MTHFD1;ALDH1L1;CYP2C8 GO:0042493| response to drug MTHFR;UGT1A1;CREB1;ABCB1;ABCC2 GO:0006810| transport ABCC2;ABCB1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0031100| organ regeneration ATIC;UGT1A1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCC2 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0043627| response to estrogen stimulus ABCC2;OPRK1;ESR1 GO:0001666| response to hypoxia MTHFR;CREB1 GO:1990830| SHMT1;CREB1 8730:[DB01183 DB02158] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 8731:[DB01183 DB05033] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05033|INCB7839 ADAM9 common genes common pathways GO:0071222| cellular response to lipopolysaccharide OPRK1;ADAM9;TLR4 GO:0051384| response to glucocorticoid stimulus UGT1A1;ADAM9 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;ADAM9 8732:[DB01183 DB13998] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0001889| liver development UGT1A1;PROC GO:0006629| lipid metabolic process CYP3A4;LRP1 GO:0042981| regulation of apoptotic process ESR1;CREB1;CALR GO:1990090| HSPA5;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1 GO:0043066| negative regulation of apoptotic process HSPA5;ALB;PROC GO:0009314| response to radiation OPRM1;HSPA5;OPRK1 GO:0002576| platelet degranulation ALB;VWF GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PHYH GO:0043687| post-translational protein modification ALB;PROC GO:0006355| regulation of transcription, DNA-dependent CREB1;CALR;ESR1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CALR GO:0006953| acute-phase response F2;UGT1A1 GO:0007568| aging CANX;LRP1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;F2;OPRD1;OPRM1 GO:0050821| protein stabilization CREB1;CALR GO:0032355| response to estradiol stimulus ESR1;CALR GO:0006898| receptor-mediated endocytosis ALB;CALR;LRP1;ASGR2 GO:0044267| cellular protein metabolic process PROC;ALB;F2 GO:0042220| response to cocaine OPRM1;HSPA5;OPRK1 GO:0010033| response to organic substance CREB1;CALR;UGT1A1 GO:1904646| TLR4;LRP1 GO:0010628| positive regulation of gene expression TLR4;CALR 8733:[DB01183 DB08835] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;FOLH1 GO:0006811| ion transport SLC36A1;SLCO1A2 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC36A1 8734:[DB01183 DB05460] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05460|Ezatiostat GSTP1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0071222| cellular response to lipopolysaccharide GSTP1;OPRK1;TLR4 GO:0008152| metabolic process UGT1A1;GSTP1;CES1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0045471| response to ethanol UGT1A1;OPRK1;GSTP1;OPRM1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0009636| response to toxin CES1;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0098869| ALB;GSTP1 GO:0032355| response to estradiol stimulus GSTP1;ESR1 8735:[DB01183 DB03288] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways GO:0008152| metabolic process PYGL;UGT1A1;CES1 GO:0070266| necroptosis PYGL;TLR4 8736:[DB01183 DB05299] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways GO:0006955| immune response TLR4;IL2;OPRK1;OPRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;IL2;ESR1 GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0045471| response to ethanol OPRM1;OPRK1;IL2;UGT1A1 GO:0032729| positive regulation of interferon-gamma production TLR4;IL2 GO:0030890| positive regulation of B cell proliferation IL2;TLR4 GO:0002376| immune system process TLR4;IL2 GO:0007204| elevation of cytosolic calcium ion concentration IL2;ESR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway IL2;OPRK1;OPRM1;OPRD1 GO:0050729| positive regulation of inflammatory response IL2;TLR4 8737:[DB01183 DB02105] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0032496| response to lipopolysaccharide COMT;UGT1A1;TLR4;OPRM1 GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0042493| response to drug CREB1;UGT1A1;COMT;ABCB1 GO:0043627| response to estrogen stimulus ESR1;COMT;OPRK1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;OPRK1;COMT GO:0014070| response to organic cyclic compound COMT;UGT1A1 8738:[DB01183 DB03203] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0016032| viral reproduction CREB1;PVR GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 8739:[DB01183 DB13988] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13988|SB-269970 HTR7 common genes common pathways GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;HTR7 GO:0007623| circadian rhythm CREB1;HTR7 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR7;OPRM1;OPRD1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;HTR7;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway HTR7;OPRK1;OPRM1;OPRD1 8740:[DB01183 DB07358] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07358|2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways GO:0008152| metabolic process GCK;CES1;UGT1A1 8741:[DB01183 DB11726] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11726|Encenicline CHRNA7 common genes common pathways GO:1900273| CHRNA7;CREB1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRNA7;CREB1;TLR4;OPRK1 GO:0007613| memory CREB1;CHRNA7 GO:0001666| response to hypoxia CREB1;CHRNA7 GO:0006811| ion transport CHRNA7;SLCO1A2 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CHRNA7;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA7 GO:0035094| response to nicotine CREB1;CHRNA7 8742:[DB01183 DB00011] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00011|Interferon alfa-n1 IFNAR2;IFNAR1 common genes common pathways GO:0051607| defense response to virus IFNAR2;OPRK1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;IFNAR1 8743:[DB01183 DB07841] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07841|Geranylgeranyl diphosphate FNTA;PGGT1B;FNTB;GGPS1;FDPS;RABGGTA;RABGGTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CREB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;UGT1A1;CYP2C8 GO:0043687| post-translational protein modification RABGGTB;ALB;RABGGTA GO:0016032| viral reproduction FDPS;CREB1 GO:0006695| cholesterol biosynthetic process GGPS1;CES1;FDPS GO:0042981| regulation of apoptotic process RABGGTA;CREB1;RABGGTB;ESR1 GO:0006629| lipid metabolic process CYP3A4;FDPS 8744:[DB01183 DB04657] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04657|Carboxin SDHA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;SDHA 8745:[DB01183 DB00779] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;TDO2 GO:0055085| transmembrane transport SLCO1A2;SLC22A6;ABCB1 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB 8746:[DB01183 DB01086] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes CES1;ABCB1 common pathways GO:0009636| response to toxin CES1 GO:0006811| ion transport SLCO1A2;SCN10A GO:0030855| epithelial cell differentiation CES1 GO:0055085| transmembrane transport SCN10A;ABCB1;SLCO1A2 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0090122| cholesterol ester hydrolysis involved in cholesterol transport CES1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0007600| sensory perception OPRK1;SCN10A;OPRM1 GO:1901529| ABCB1 GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1;SCN10A GO:0006695| cholesterol biosynthetic process CES1 GO:0051791| medium-chain fatty acid metabolic process CES1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0008152| metabolic process CES1;UGT1A1 8747:[DB01183 DB00858] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;TLR4;CREB1 GO:0060065| uterus development CYP19A1;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;CYP2C8 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;AR;CREB1;TLR4;OPRK1 GO:0006810| transport AR;ABCB1 GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0016579| protein deubiquitination AR;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0030879| mammary gland development CYP19A1;CREB1 8748:[DB01183 DB01562] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 8749:[DB01183 DB08042] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08042|N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0006468| protein phosphorylation KDR;CREB1 GO:0030154| cell differentiation CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;TLR4 GO:0043066| negative regulation of apoptotic process KDR;ALB GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0010629| negative regulation of gene expression KDR;CREB1;ESR1;OPRD1 GO:0016032| viral reproduction KDR;CREB1 8750:[DB01183 DB06554] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06554|Gaboxadol SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLC36A1;ABCB1 GO:0006811| ion transport SLC36A1;SLCO1A2 8751:[DB01183 DB08363] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08363|1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine TP53 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;TP53 GO:0016579| protein deubiquitination TP53;ESR1 GO:0048511| rhythmic process TP53;CREB1 GO:0010628| positive regulation of gene expression TP53;TLR4 GO:0006366| transcription from RNA polymerase II promoter CREB1;TP53;ESR1 GO:0014070| response to organic cyclic compound TP53;UGT1A1 GO:0007568| aging CREB1;TP53 GO:0030154| cell differentiation TP53;CREB1 GO:0071456| cellular response to hypoxia TP53;OPRD1 GO:0016032| viral reproduction CREB1;TP53 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;TP53;CREB1 GO:0042493| response to drug CREB1;TP53;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;TP53;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP53;ESR1 GO:0042981| regulation of apoptotic process CREB1;TP53;ESR1 GO:0043066| negative regulation of apoptotic process TP53;ALB GO:0043065| positive regulation of apoptotic process CREB1;TP53 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;TP53 GO:0006351| transcription, DNA-dependent ESR1;TP53;CREB1 GO:0045471| response to ethanol TP53;UGT1A1;OPRK1;OPRM1 GO:0042060| wound healing OPRM1;TP53 8752:[DB01183 DB02853] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02853|D-Proline SLC36A1 common genes common pathways GO:0006811| ion transport SLCO1A2;SLC36A1 GO:0055085| transmembrane transport SLCO1A2;SLC36A1;ABCB1 8753:[DB01183 DB04275] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04275|N-acetylserotonin SPR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;SPR;CYP3A4 8754:[DB01183 DB00016] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00016|Erythropoietin EPOR common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;EPOR;ESR1 8755:[DB01183 DB13875] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13875|Harmaline HNMT common genes common pathways 8756:[DB01183 DB06704] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLCO1A2 GO:0042493| response to drug SLC6A2;UGT1A1;CREB1;ABCB1 GO:0007268| synaptic transmission SLC6A2;OPRK1;OPRD1;OPRM1 8757:[DB01183 DB06226] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06226|Nelipepimut-S HLA-A;HLA-A common genes common pathways GO:0002376| immune system process HLA-A;TLR4 GO:0006955| immune response OPRD1;HLA-A;OPRK1;TLR4 GO:0016032| viral reproduction HLA-A;CREB1 8758:[DB01183 DB03121] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03121|(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid PLA2G2A common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;PLA2G2A;TLR4 GO:0050729| positive regulation of inflammatory response PLA2G2A;TLR4 GO:0006629| lipid metabolic process CYP3A4;PLA2G2A 8759:[DB01183 DB07757] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;CREB1;TLR4 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;ESR2 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;ESR2;OPRK1 8760:[DB01183 DB04367] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04367|Debromohymenialdisine TNK2;CLK1 common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;TNK2;ESR1 GO:0030154| cell differentiation TNK2;CREB1 GO:0006468| protein phosphorylation CREB1;TNK2;CLK1 GO:0045087| innate immune response TLR4;TNK2 8761:[DB01183 DB09322] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09322|Zinc sulfate ALPPL2 common genes common pathways GO:0008152| metabolic process UGT1A1;ALPPL2;CES1 8762:[DB01183 DB08553] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BRAF GO:1990090| BRAF;CREB1 GO:0008542| visual learning CREB1;BRAF GO:0006468| protein phosphorylation CREB1;BRAF GO:0030154| cell differentiation BRAF;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BRAF GO:0007165| signal transduction CREB1;TLR4;OPRK1;BRAF;ESR1;OPRM1;OPRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;BRAF;OPRM1 GO:0010628| positive regulation of gene expression BRAF;TLR4 8763:[DB01183 DB07544] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;BCAT1 8764:[DB01183 DB04178] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04178|Di-Stearoyl-3-Sn-Phosphatidylcholine BPI;SLC25A4 common genes common pathways GO:0016032| viral reproduction CREB1;SLC25A4 GO:0006955| immune response OPRK1;TLR4;BPI;OPRD1 GO:0042742| defense response to bacterium TLR4;BPI GO:0050829| defense response to Gram-negative bacterium TLR4;BPI GO:0071222| cellular response to lipopolysaccharide OPRK1;BPI;TLR4 GO:0055085| transmembrane transport SLC25A4;ABCB1;SLCO1A2 GO:0032715| negative regulation of interleukin-6 production BPI;TLR4 GO:0032720| negative regulation of tumor necrosis factor production TLR4;BPI GO:0006810| transport ABCB1;SLC25A4 8765:[DB01183 DB00142] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0042493| response to drug ABAT;GAD1;ABCB1;PFAS;SLC1A2;SLC1A3;GAD2;UGT1A1;CREB1;GCLM;GRIN2A GO:0007268| synaptic transmission GRIA1;GAD1;GRIK4;GRM7;GRM1;OPRK1;GAD2;SLC1A3;SLC1A2;SLC1A1;GRIK5;GRIK1;SLC1A6;GRIA2;GRIN2A;GRM4;OPRD1;OPRM1;GLS;GRIK2;GRIN2B GO:0032094| response to food OPRM1;SLC16A1 GO:0055114| oxidation-reduction process AASS;ALDH18A1;CYP2C8;CYP3A4;GLUD1;GLUD2 GO:0051924| regulation of calcium ion transport OPRD1;GRIN3B GO:0035094| response to nicotine CREB1;ABAT;SLC7A11 GO:0043278| response to morphine OPRK1;OPRM1;GRIN1 GO:0008542| visual learning GRIN1;GRIN2A;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2B;GRIK2;GRIN2D;GRIN1;GRIA3;OPRM1;GRIN2A;GRIA2;GRIK1;GRID1;GRIN3A;GRID2;GRIA4;GRIN2C;GRIK3;GRIK5;GRIN3B;GRIK4;GRIA1 GO:0045471| response to ethanol GRIN2A;GRIN2B;GRIN1;OPRM1;OPRK1;ABAT;GOT2;GRIN3A;UGT1A1 GO:0019233| sensory perception of pain GRIN2A;GRIN1;OPRM1;OPRD1;GRM1;OPRK1 GO:0001889| liver development FPGS;ASNS;UGT1A1 GO:0007626| locomotory behavior OPRM1;GRM1;OPRK1;ABAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;GRIN1 GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;CREB1 GO:0043066| negative regulation of apoptotic process ASNS;GCLC;ALB GO:0048148| behavioral response to cocaine ABAT;OPRK1 GO:0008152| metabolic process FOLH1;BCAT1;CES1;EPRS;FTCD;ALDH18A1;UGT1A1;AASS;BCAT2 GO:0042981| regulation of apoptotic process ESR1;CREB1;GLS2 GO:0071260| cellular response to mechanical stimulus TLR4;GCLC GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0051930| regulation of sensory perception of pain GRM1;OPRK1;OPRD1;OPRM1;GRIN2D;GRIN2A GO:0006811| ion transport GRIN2A;SLC1A6;GRIA2;GRIK1;GRIN2B;GRIK2;GRIN2D;GRIN1;GRIA3;SLCO1A2;GRIK5;SLC1A1;SLC1A2;SLC1A3;GRIN3B;GRIK4;GRIA1;SLC1A7;GRID1;GRIN3A;SLC25A22;SLC25A18;GRID2;GRIA4;GRIN2C;GRIK3 GO:0014070| response to organic cyclic compound TAT;UGT1A1 GO:0009636| response to toxin SLC7A11;ASNS;CES1 GO:0055085| transmembrane transport SLCO1A2;SLC16A10;GRIK2;GRIK1;SLC16A1;GRIK3;SLC25A18;SLC25A22;SLC1A7;GRIK4;ABCB1;GRIK5 GO:0008344| adult locomotory behavior GRIN1;GRIN2D;OPRD1 GO:0042220| response to cocaine OPRM1;ABAT;OPRK1 GO:0000187| activation of MAPK activity GRM4;TLR4;GRM1 GO:1990830| BCAT2;CREB1;GCLM GO:1903428| TLR4;GRIN1 GO:0001666| response to hypoxia ABAT;CREB1 GO:1904646| GRIN1;GRIN2A;TLR4 GO:0007584| response to nutrient GCLM;UGT1A1;GCLC GO:0014823| response to activity GCLC;CREB1;GCLM GO:0007186| G-protein coupled receptor signaling pathway GRM7;GRM1;OPRK1;OPRM1;OPRD1;GRM4;GRM8 GO:0051384| response to glucocorticoid stimulus GOT1;UGT1A1;TAT GO:0009267| cellular response to starvation ALB;GLUL GO:0007613| memory CREB1;GRIN1;GRIN2A GO:0006810| transport GRID2;GRIA4;GRIN2C;ABCB1;GRIK4;GRIN2B;GRIK2;GRIA3;GRIN2A;GRIK1 GO:0007568| aging ABAT;CREB1;GCLM;GCLC GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;GRM8;OPRK1;GRM7 GO:0070588| calcium ion transmembrane transport GRIN3B;GRIN3A;OPRM1 GO:0031100| organ regeneration UGT1A1;FPGS GO:0035729| cellular response to hepatocyte growth factor stimulus CREB1;GCLM;GCLC GO:1900273| GRIN2A;CREB1 GO:0032870| cellular response to hormone stimulus UGT1A1;ASNS GO:0007165| signal transduction TLR4;CREB1;GRM1;OPRK1;GRIA1;GRM7;ESR1;OPRD1;OPRM1;GRM4;GRM8;GRIA2 8766:[DB01183 DB07444] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways GO:0007165| signal transduction ESR1;DAPK1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0006468| protein phosphorylation DAPK1;CREB1 GO:0042981| regulation of apoptotic process ESR1;DAPK1;CREB1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;DAPK1 GO:0043066| negative regulation of apoptotic process DAPK1;ALB GO:0097190| apoptotic signaling pathway TLR4;DAPK1 8767:[DB01183 DB11842] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11842|Angiotensin II AGTR1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway AGTR1;OPRM1;OPRD1;OPRK1 GO:0050729| positive regulation of inflammatory response TLR4;AGTR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;AGTR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;AGTR1;CREB1;TLR4;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;AGTR1;OPRK1 GO:0050727| regulation of inflammatory response AGTR1;ESR1;TLR4 8768:[DB01183 DB13173] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;IGF2R GO:0031100| organ regeneration IGF2R;UGT1A1 GO:0006898| receptor-mediated endocytosis ALB;IGF2R GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;IGF2R;CREB1;OPRK1 GO:0001889| liver development IGF2R;UGT1A1 GO:0043065| positive regulation of apoptotic process IGF2R;CREB1 GO:0042981| regulation of apoptotic process CREB1;IGF2R;ESR1 8769:[DB01183 DB06680] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06680|Asoprisnil PGR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PGR GO:0010629| negative regulation of gene expression CREB1;PGR;ESR1;OPRD1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PGR GO:0006351| transcription, DNA-dependent CREB1;PGR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PGR;CREB1;TLR4 GO:0030879| mammary gland development PGR;CREB1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;PGR;OPRK1 8770:[DB01183 DB05120] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05120|AT1391 INSR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;INSR;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;TLR4;OPRM1;ESR1 GO:0006468| protein phosphorylation INSR;CREB1 GO:0007613| memory CREB1;INSR GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;INSR;OPRK1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;INSR GO:0008584| male gonad development INSR;ESR1 GO:0000187| activation of MAPK activity TLR4;INSR 8771:[DB01183 DB09207] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;DRD2;OPRK1;DRD3 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:1900273| DRD2;CREB1 GO:0007165| signal transduction OPRK1;DRD2;CREB1;TLR4;DRD3;ESR1;OPRM1;OPRD1 GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 GO:0042220| response to cocaine OPRM1;DRD3;DRD2;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRK1;DRD2;DRD3;UGT1A1;OPRM1 GO:0048148| behavioral response to cocaine DRD3;DRD2;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD3 GO:0007626| locomotory behavior DRD2;OPRK1;DRD3;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TLR4;CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug DRD3;CREB1;UGT1A1;DRD2;ABCB1 GO:0035094| response to nicotine CREB1;DRD2 GO:0008542| visual learning DRD3;CREB1;DRD2 GO:0043278| response to morphine OPRM1;DRD3;DRD2;OPRK1 8772:[DB01183 DB04094] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A GO:0070588| calcium ion transmembrane transport FKBP1A;OPRM1 GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CREB1 8773:[DB01183 DB04719] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04719|DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE CSNK2A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ESR1;CREB1 GO:0006351| transcription, DNA-dependent CSNK2A1;ESR1;CREB1 GO:0048511| rhythmic process CREB1;CSNK2A1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0007165| signal transduction OPRM1;CSNK2A1;OPRD1;ESR1;CREB1;TLR4;OPRK1 8774:[DB01183 DB08871] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0035094| response to nicotine BCL2;CREB1 GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0051607| defense response to virus BCL2;OPRK1 GO:0042493| response to drug BCL2;ABCB1;CREB1;UGT1A1 GO:0042981| regulation of apoptotic process ESR1;BCL2;CREB1 GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0009314| response to radiation OPRM1;BCL2;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;BCL2 GO:0030890| positive regulation of B cell proliferation BCL2;TLR4 GO:0008584| male gonad development BCL2;ESR1 GO:0051881| regulation of mitochondrial membrane potential BCL2;OPRD1 GO:0055085| transmembrane transport SLCO1A2;BCL2;ABCB1 GO:0009636| response to toxin CES1;BCL2 GO:0007409| axonogenesis CREB1;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;OPRD1 GO:0048545| response to steroid hormone stimulus UGT1A1;BCL2 GO:0040018| positive regulation of multicellular organism growth BCL2;CREB1 GO:0071456| cellular response to hypoxia BCL2;OPRD1 GO:0051384| response to glucocorticoid stimulus BCL2;UGT1A1 8775:[DB01183 DB04462] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04462|Tetrabromo-2-Benzotriazole CSNK2A1 common genes common pathways GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;CSNK2A1;OPRM1;ESR1 GO:0048511| rhythmic process CSNK2A1;CREB1 GO:0006351| transcription, DNA-dependent CSNK2A1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ESR1;CREB1 8776:[DB01183 DB05996] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways GO:1901215| GPNMB;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;GPNMB GO:0008285| negative regulation of cell proliferation OPRM1;GPNMB GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;GPNMB;OPRD1;ESR1 GO:0032720| negative regulation of tumor necrosis factor production GPNMB;TLR4 8777:[DB01183 DB04197] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04197|Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ARG1 GO:0045087| innate immune response TLR4;ARG1 GO:0071222| cellular response to lipopolysaccharide ARG1;TLR4;OPRK1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;ARG1 GO:0001889| liver development ARG1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ARG1;OPRM1 GO:0048545| response to steroid hormone stimulus UGT1A1;ARG1 GO:0002376| immune system process ARG1;TLR4 GO:0007568| aging CREB1;ARG1 8778:[DB01183 DB13894] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13894|Agkistrodon piscivorus antivenin PLA2G10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G10 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity PLA2G10;ESR1 GO:0007411| axon guidance CREB1;PLA2G10 GO:1990830| PLA2G10;CREB1 8779:[DB01183 DB05915] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05915|MYO-029 MSTN common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;MSTN GO:0043627| response to estrogen stimulus OPRK1;MSTN;ESR1 GO:0007179| transforming growth factor beta receptor signaling pathway MSTN;CREB1 GO:0042981| regulation of apoptotic process MSTN;ESR1;CREB1 GO:0045471| response to ethanol MSTN;OPRM1;OPRK1;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;MSTN 8780:[DB01183 DB03381] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03381|Hexadecanal RHO;DBI common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;RHO;OPRK1 GO:0006468| protein phosphorylation CREB1;RHO GO:0007165| signal transduction OPRK1;RHO;CREB1;TLR4;OPRM1;OPRD1;ESR1 8781:[DB01183 DB07981] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0098869| ALB;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CES1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4 GO:0006954| inflammatory response PTGS1;TLR4 8782:[DB01183 DB03048] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP3A4;CYP2C8 8783:[DB01183 DB01106] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways GO:0006954| inflammatory response TLR4;HRH1 GO:0007600| sensory perception OPRK1;NTSR2;OPRM1 GO:0008542| visual learning CREB1;HRH1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;ESR1;NTSR2;OPRK1 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1;NTSR2 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HRH1;OPRD1;NTSR2;OPRK1 GO:0007613| memory CREB1;HRH1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;HRH1;OPRK1;NTSR2;CREB1;TLR4 8784:[DB01183 DB01210] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0007165| signal transduction TLR4;CREB1;ADRB1;OPRK1;OPRD1;OPRM1;ADRB2;ESR1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;OPRK1;OPRM1;OPRD1;ADRB2 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:1904646| ADRB2;TLR4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ADRB2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 8785:[DB01183 DB02556] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;CRH GO:0045471| response to ethanol OPRK1;CRH;UGT1A1;OPRM1 GO:0006954| inflammatory response TLR4;CRH GO:0042493| response to drug ABCB1;CREB1;CRH;UGT1A1 GO:0007268| synaptic transmission OPRK1;CRH;OPRD1;OPRM1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;CRH GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CRH;CREB1;TLR4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway CRH;OPRK1;OPRD1;OPRM1 GO:0008202| steroid metabolic process CYP2C8;CRH;UGT1A1;CYP3A4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;CRH GO:0030154| cell differentiation SLC7A5;CREB1 GO:0006810| transport ABCB1;SLC7A5 GO:0010628| positive regulation of gene expression TLR4;CRH GO:0033685| negative regulation of luteinizing hormone secretion CRH;OPRK1 GO:0043627| response to estrogen stimulus ESR1;CRH;OPRK1 GO:0055085| transmembrane transport SLC16A10;SLCO1A2;ABCB1 GO:0042220| response to cocaine OPRK1;CRH;OPRM1 8786:[DB01183 DB06217] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0006811| ion transport SCN5A;KCND3;KCNH2;SLCO1A2;KCNA5 GO:0055085| transmembrane transport KCNA5;ABCB1;KCND3;SCN5A;KCNH2;SLCO1A2 GO:0001666| response to hypoxia KCNA5;CREB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance KCNA5;CREB1;UGT1A1 GO:1901381| KCNH2;OPRK1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0051481| reduction of cytosolic calcium ion concentration KCNA5;OPRM1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 8787:[DB01183 DB02570] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02570|PD150606 CAPNS1 common genes common pathways 8788:[DB01183 DB07960] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;NEU2 GO:0008152| metabolic process UGT1A1;CES1;NEU2 8789:[DB01183 DB02266] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0008584| male gonad development AR;ESR1;AKR1C3 GO:0001666| response to hypoxia PPARA;CREB1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0048511| rhythmic process PPARA;PPARG;CREB1 GO:0007584| response to nutrient AKR1C3;UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation AR;OPRM1;PTGS2;PPARG GO:0010033| response to organic substance PPARG;CREB1;UGT1A1;PTGS2 GO:0016579| protein deubiquitination AR;ESR1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;PPARG GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0055085| transmembrane transport SLCO1A2;SLC22A6;ABCB1 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0044267| cellular protein metabolic process TTR;ALB GO:0031100| organ regeneration UGT1A1;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TLR4 GO:0098869| PTGS1;PTGS2;ALB GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0007165| signal transduction TLR4;CREB1;PPARG;OPRK1;OPRD1;OPRM1;ESR1;AR GO:0015711| organic anion transport SLC22A6;SLCO1A2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRD1;AKR1C3;OPRM1 GO:0009267| cellular response to starvation ALB;AKR1C3 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLCO1A2 GO:0008202| steroid metabolic process AKR1C3;CYP3A4;UGT1A1;CYP2C8 GO:0007613| memory CREB1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007568| aging CREB1;PTGS2 GO:0006810| transport ABCB1;AR;TTR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006954| inflammatory response PTGS1;PTGS2;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARA;PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;ESR1;AR;PPARG GO:0042493| response to drug PPARG;CREB1;UGT1A1;ABCB1;PTGS2 GO:0006355| regulation of transcription, DNA-dependent AR;PPARA;ESR1;CREB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARA;ESR1;PPARG;CREB1 GO:1901215| PPARA;CREB1 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;PTGS2;AKR1C3;CYP2C8 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARA;ESR1;TLR4;CREB1;PPARG GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;PTGS1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;AR;PPARA;ESR1 GO:0045087| innate immune response TLR4;PPARG GO:0060749| mammary gland alveolus development AR;ESR1 GO:0006629| lipid metabolic process PPARG;PTGS1;PPARA;CYP3A4;PTGS2 GO:0042594| response to starvation UGT1A1;PPARG GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR;ESR1 GO:0042060| wound healing OPRM1;PPARA GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;PTGS2 GO:0000060| protein import into nucleus, translocation AKR1C3;OPRD1 GO:0043401| steroid hormone mediated signaling pathway AR;PPARA;ESR1;PPARG GO:0019233| sensory perception of pain OPRK1;PTGS2;OPRM1;OPRD1 GO:0006351| transcription, DNA-dependent AR;PPARA;ESR1;CREB1;PPARG 8790:[DB01183 DB02377] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0042493| response to drug UGT1A1;PNP;CREB1;ABCB1 GO:0006955| immune response OPRD1;TLR4;PNP;OPRK1 GO:0051000| positive regulation of nitric-oxide synthase activity GCH1;ESR1 GO:0032496| response to lipopolysaccharide GCH1;OPRM1;TLR4;UGT1A1 GO:0008152| metabolic process CES1;GCH1;UGT1A1 8791:[DB01183 DB12305] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0045471| response to ethanol OPRK1;SLC6A3;UGT1A1;OPRM1 GO:0007626| locomotory behavior OPRK1;SLC6A3;OPRM1 GO:0007268| synaptic transmission OPRK1;SLC6A2;OPRD1;OPRM1 GO:0042493| response to drug SLC6A4;SLC6A3;ABCB1;CREB1;SLC6A2;UGT1A1 GO:0035094| response to nicotine SLC6A3;CREB1 GO:0007595| lactation SLC6A3;CREB1 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging CREB1;SLC6A3 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007613| memory SLC6A4;CREB1 GO:0009636| response to toxin SLC6A4;CES1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0042220| response to cocaine OPRM1;OPRK1;SLC6A3 GO:0055085| transmembrane transport SLC6A4;SLCO1A2;SLC6A3;ABCB1;SLC6A2 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0010033| response to organic substance SLC6A4;UGT1A1;CREB1 GO:0007584| response to nutrient SLC6A4;UGT1A1 8792:[DB01183 DB01619] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01619|Phenindamine HRH1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;HRH1;OPRM1 GO:0007613| memory CREB1;HRH1 GO:0007165| signal transduction ESR1;HRH1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;HRH1;OPRK1 GO:0006954| inflammatory response HRH1;TLR4 GO:0008542| visual learning CREB1;HRH1 8793:[DB01183 DB05892] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05892|RI 624 NGF common genes common pathways GO:0010628| positive regulation of gene expression TLR4;NGF GO:0043066| negative regulation of apoptotic process ALB;NGF GO:0043065| positive regulation of apoptotic process NGF;CREB1 8794:[DB01183 DB07425] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07425|Sobetirome THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;THRB;TLR4;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;THRB GO:0006351| transcription, DNA-dependent ESR1;THRB;CREB1 GO:0060509| Type I pneumocyte differentiation THRB;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter THRB;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;THRB;ESR1 8795:[DB01183 DB02942] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 8796:[DB01183 DB12752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12752|Bucindolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 8797:[DB01183 DB00973] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes CYP2C8;UGT1A1;ABCB1;CYP3A4 common pathways GO:0042493| response to drug ABCG8;ABCB1;ABCG5;ABCC2;NPC1L1;ABCG2;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A3 GO:0006789| bilirubin conjugation UGT1A1 GO:0008209| androgen metabolic process UGT2B7;ESR1;CYP3A4 GO:0052695| cellular glucuronidation UGT1A3;UGT2B7;UGT2B15;UGT1A1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0099040| ABCB1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0016032| viral reproduction CREB1;ANPEP GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ABCC2;OPRM1 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1 GO:0070980| biphenyl catabolic process UGT1A1 GO:1904224| UGT1A1;UGT1A3 GO:0042737| drug catabolic process CYP3A4 GO:0006695| cholesterol biosynthetic process NPC1L1;CES1 GO:0001889| liver development UGT1A1 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABCC2;TLR4 GO:0006805| xenobiotic metabolic process UGT2B15;CYP2C8;CES1;CYP3A4 GO:0008152| metabolic process UGT2B7;UGT1A3;CES1;UGT2B15;UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0006082| organic acid metabolic process CYP2C8 GO:0071361| cellular response to ethanol UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0006629| lipid metabolic process NPC1L1;UGT2B7;CYP3A4;SOAT1 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0007586| digestion UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0006811| ion transport SLCO1A2;SLCO1B1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A3;UGT1A1 GO:0002933| CYP2C8;CYP3A4 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0014070| response to organic cyclic compound UGT1A1 GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCG5;ABCB1;ABCC3 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;ABCC2;ABCB1;ABCG5;ABCG8;ABCC3;ABCB11;SLCO1B1;SLCO1A2 GO:0036378| CYP3A4 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;ABCB11;ALB;ABCC3 GO:0042359| vitamin D metabolic process CYP3A4 GO:0043627| response to estrogen stimulus ESR1;ABCC2;OPRK1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007584| response to nutrient ABCG8;ABCG5;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A3 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A3 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0072089| stem cell proliferation ABCB1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1A2 GO:0045332| phospholipid translocation ABCB1 GO:0008202| steroid metabolic process NPC1L1;CYP2C8;UGT1A1;UGT2B15;UGT2B7;SOAT1;CYP3A4 GO:0042167| heme catabolic process UGT1A1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0030154| cell differentiation ANPEP;CREB1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC3 GO:0006810| transport ABCG2;ABCC2;ABCB1;ABCC3;ABCB11 GO:0031100| organ regeneration UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0007165| signal transduction ESR1;ANPEP;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A3;UGT1A1;CYP2C8 GO:0097267| CYP2C8 GO:0015711| organic anion transport SLCO1B1;SLCO1A2 8798:[DB01183 DB11723] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11723|Dutogliptin DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8799:[DB01183 DB04153] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;ADH5 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;ADH5 8800:[DB01183 DB05740] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;CHRNA9;CHRNA10 GO:0007613| memory CHRNA7;CREB1;CHRNB2 GO:0007165| signal transduction TLR4;CHRNA9;CREB1;CHRNB2;OPRK1;CHRNA10;ESR1;OPRD1;OPRM1;CHRNA7;CHRNA2;CHRNA4 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1;CHRNA10;CHRNA9 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:1900273| CHRNA7;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CHRNA7;TLR4 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0042220| response to cocaine OPRM1;CHRNB2;OPRK1 GO:0006811| ion transport CHRNB2;CHRNA9;CHRNA10;SLCO1A2;CHRNA2;CHRNA4;CHRNA7 GO:0030890| positive regulation of B cell proliferation TLR4;CHRNB2 GO:0001666| response to hypoxia CREB1;CHRNB2;CHRNA7;CHRNA4 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA9;CHRNB2;CHRNA10;OPRM1;CHRNA7;CHRNA2;CHRNA4 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1;CHRNB2 GO:0019233| sensory perception of pain OPRK1;CHRNB2;CHRNA4;OPRD1;OPRM1 GO:0033603| positive regulation of dopamine secretion OPRK1;CHRNB2 GO:0007626| locomotory behavior OPRK1;CHRNB2;CHRNA4;OPRM1 GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1;CHRNA4 GO:0035094| response to nicotine CHRNB2;CREB1;CHRNA2;CHRNA4;CHRNA7 GO:0008542| visual learning CHRNB2;CREB1 8801:[DB01183 DB03756] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent SREBF1;RXRG;PPARG;CREB1;RXRB;RXRA;ESR1;PPARA GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;SREBF1;UGT1A1;PPARG;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;ESR1;CREB1;PPARG;RXRA;SREBF1 GO:0032094| response to food OPRM1;SREBF1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C9 GO:1901215| PPARA;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0016032| viral reproduction RXRA;CREB1 GO:0042752| regulation of circadian rhythm PPARA;PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRG;PPARG;RXRA;RXRB;ESR1;PPARA GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;SREBF1;ESR1 GO:0007623| circadian rhythm CREB1;SREBF1 GO:0042060| wound healing OPRM1;PPARA GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006351| transcription, DNA-dependent SREBF1;RXRG;RXRB;RXRA;PPARG;CREB1;ESR1;PPARA GO:0043401| steroid hormone mediated signaling pathway PPARA;ESR1;RXRG;PPARG;RXRA;RXRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARA;PPARG;CREB1;RXRB;TLR4;RXRA;SREBF1;RXRG GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0071398| cellular response to fatty acid SREBF1;CREB1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C9 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;SREBF1;PPARA;ESR1 GO:0045087| innate immune response TLR4;PPARG GO:0033762| response to glucagon stimulus SREBF1;CREB1 GO:0006629| lipid metabolic process CYP2C9;PPARG;SREBF1;PPARA;CYP3A4 GO:0042594| response to starvation UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1;SREBF1 GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0015721| bile acid and bile salt transport RXRA;ALB;SLCO1A2 GO:0001666| response to hypoxia PPARA;CREB1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process PPARG;CREB1;PPARA GO:0043627| response to estrogen stimulus ESR1;OPRK1;PPARG GO:0010033| response to organic substance UGT1A1;CREB1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;FABP7;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0008202| steroid metabolic process CYP3A4;SREBF1;CYP2C8;UGT1A1;CYP2C9 GO:0009267| cellular response to starvation ALB;SREBF1 GO:0007568| aging CREB1;SREBF1 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0031100| organ regeneration UGT1A1;PPARG GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;PPARG;CREB1;OPRK1 8802:[DB01183 DB00399] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1;SLCO1A2 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1;UGT1A1;CREB1 GO:0016032| viral reproduction CREB1;FDPS GO:0006695| cholesterol biosynthetic process GGPS1;CES1;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 8803:[DB01183 DB06362] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways GO:0048511| rhythmic process TOP2A;CREB1 GO:0007409| axonogenesis CREB1;TOP2B GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;CREB1;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A 8804:[DB01183 DB04768] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 8805:[DB01183 DB03052] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;TBXAS1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;TBXAS1 8806:[DB01183 DB05241] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05241|XL765 PIK3CA;PIK3CG;PIK3CD;PIK3CB;MTOR common genes common pathways GO:0009267| cellular response to starvation MTOR;ALB GO:0007186| G-protein coupled receptor signaling pathway PIK3CG;OPRK1;PIK3CB;OPRM1;OPRD1;PIK3CA GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;PIK3CG GO:0071456| cellular response to hypoxia MTOR;OPRD1 GO:0030154| cell differentiation PIK3CD;CREB1 GO:0006468| protein phosphorylation MTOR;PIK3CD;PIK3CG;CREB1;PIK3CA GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;MTOR;ESR1;OPRM1 GO:0002376| immune system process TLR4;PIK3CG;PIK3CD GO:0007165| signal transduction OPRK1;TLR4;CREB1;MTOR;PIK3CD;PIK3CB;ESR1;OPRD1;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PIK3CA GO:0042220| response to cocaine MTOR;OPRK1;OPRM1 GO:0000187| activation of MAPK activity PIK3CB;TLR4 GO:0050769| positive regulation of neurogenesis MTOR;OPRM1 GO:0032868| response to insulin stimulus MTOR;OPRK1 GO:0010628| positive regulation of gene expression TLR4;MTOR;PIK3CD;PIK3CB GO:0007411| axon guidance CREB1;PIK3CD;PIK3CA;PIK3CB GO:0007584| response to nutrient MTOR;UGT1A1 GO:0046889| positive regulation of lipid biosynthetic process MTOR;CREB1 GO:0042060| wound healing OPRM1;MTOR GO:0001889| liver development PIK3CA;UGT1A1 GO:0045087| innate immune response PIK3CB;PIK3CA;PIK3CG;TLR4;PIK3CD GO:0008361| regulation of cell size CREB1;MTOR GO:0043491| protein kinase B signaling cascade CREB1;PIK3CA GO:0006954| inflammatory response PIK3CD;TLR4;PIK3CG;PIK3CB;PIK3CA GO:0043278| response to morphine OPRK1;MTOR;OPRM1 GO:0008542| visual learning MTOR;CREB1 8807:[DB01183 DB00473] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways GO:0006811| ion transport SCN5A;SLCO1A2;SCN10A GO:0055085| transmembrane transport SCN10A;ABCB1;SLCO1A2;SCN5A GO:0019233| sensory perception of pain OPRK1;SCN10A;OPRM1;OPRD1 GO:0007600| sensory perception SCN10A;OPRK1;OPRM1 8808:[DB01183 DB02467] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways GO:0043687| post-translational protein modification ALB;RAB5A 8809:[DB01183 DB08103] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process ALB;TTR 8810:[DB01183 DB03147] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0009636| response to toxin MAOB;NQO1;CES1;AIFM1 GO:0014070| response to organic cyclic compound UGT1A1;NQO1 GO:0001666| response to hypoxia CREB1;NOS1 GO:0007584| response to nutrient POR;UGT1A1;NQO1 GO:1902065| CREB1;AIFM1 GO:0008202| steroid metabolic process CYP3A4;CYB5R3;UGT1A1;FDXR;CYP2C8;CYB5R1 GO:0032355| response to estradiol stimulus NQO1;ESR1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;NOS1 GO:0007568| aging CREB1;NQO1;DLD GO:0071392| cellular response to estradiol stimulus ESR1;AIFM1;UGT1A1 GO:0098869| TXNRD1;GSR;ALB GO:0007165| signal transduction OPRK1;TLR4;CREB1;TXNRD1;OPRD1;OPRM1;ESR1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0043086| negative regulation of catalytic activity UGT1A1;NQO1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NOS1;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NOS1 GO:0010629| negative regulation of gene expression XDH;OPRD1;ESR1;CREB1 GO:0042493| response to drug ABCB1;POR;UGT1A1;MAOB;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;ACAD8 GO:0055114| oxidation-reduction process MAOA;XDH;CYP3A4;CYB5R3;DPYD;ACAD8;TXNRD1;DLD;AIFM1;ACADS;ACADM;MAOB;NQO2;IL4I1;IVD;FDXR;NOS1;NQO1;ACOX1;POR;GCDH;CYB5R1;DAO;GFER;GSR;NDUFA9;CYP2C8;ERO1B GO:0016032| viral reproduction TPR;CREB1 GO:0007595| lactation XDH;CREB1 GO:0007623| circadian rhythm NDUFA9;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;MAOB;UGT1A1;TLR4 GO:0006695| cholesterol biosynthetic process CYB5R3;CES1 GO:0001889| liver development UGT1A1;GFER GO:0006351| transcription, DNA-dependent ESR1;ACAD8;CREB1 GO:0045471| response to ethanol OPRK1;NQO1;MAOB;UGT1A1;OPRM1 GO:0051791| medium-chain fatty acid metabolic process ACADM;CES1 GO:0006805| xenobiotic metabolic process NQO1;NQO2;CYP2C8;POR;CYP3A4;CYB5R3;CES1 GO:0008152| metabolic process ACADS;ACAD8;CES1;GCDH;ACOX1;IVD;UGT1A1;ACADM GO:0043066| negative regulation of apoptotic process POR;ALB;NQO1 GO:0002576| platelet degranulation CYB5R1;ALB GO:0043065| positive regulation of apoptotic process CREB1;AIFM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;NOS1;CREB1;ESR1 GO:0006629| lipid metabolic process CYB5R1;ACOX1;FDXR;ACADM;ACADS;ACAD8;CYB5R3;CYP3A4 GO:1900745| XDH;OPRK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;ESR1 8811:[DB01183 DB03485] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03485|Alpha-D-Fucose LTF common genes common pathways GO:0002376| immune system process TLR4;LTF GO:0001895| retina homeostasis LTF;ALB GO:0044267| cellular protein metabolic process ALB;LTF GO:0006811| ion transport SLCO1A2;LTF GO:0045087| innate immune response LTF;TLR4 GO:0043066| negative regulation of apoptotic process LTF;ALB GO:0050829| defense response to Gram-negative bacterium TLR4;LTF GO:0006351| transcription, DNA-dependent LTF;ESR1;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;LTF GO:0042742| defense response to bacterium TLR4;LTF GO:0006355| regulation of transcription, DNA-dependent LTF;ESR1;CREB1 8812:[DB01183 DB14562] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14562|Andexanet alfa TFPI common genes common pathways GO:0032355| response to estradiol stimulus TFPI;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;TFPI;OPRK1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;TFPI 8813:[DB01183 DB05252] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide TLR4;NOS2;UGT1A1;OPRM1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;NOS2 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process NOS2;CYP2C8;CYP3A4 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0009617| response to bacterium NOS2;TLR4 GO:0010629| negative regulation of gene expression ESR1;OPRD1;NOS2;CREB1 GO:0001666| response to hypoxia NOS2;CREB1 8814:[DB01183 DB07168] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways GO:0051924| regulation of calcium ion transport OPRD1;CAMK2B GO:0006468| protein phosphorylation CAMK2B;CREB1 GO:0030154| cell differentiation CREB1;CAMK2B GO:0007165| signal transduction OPRD1;OPRM1;CAMK2B;ESR1;TLR4;CREB1;OPRK1 8815:[DB01183 DB01927] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01927|Duroquinone NQO1 common genes common pathways GO:0007584| response to nutrient NQO1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;NQO1 GO:0009636| response to toxin CES1;NQO1 GO:0007568| aging NQO1;CREB1 GO:0032355| response to estradiol stimulus NQO1;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NQO1 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0006805| xenobiotic metabolic process CES1;CYP3A4;NQO1;CYP2C8 GO:0045471| response to ethanol OPRM1;OPRK1;NQO1;UGT1A1 8816:[DB01183 DB08995] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08995|Diosmin AHR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;AHR;ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;AHR;CYP3A4;CES1 GO:0006351| transcription, DNA-dependent ESR1;AHR;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;ESR1 GO:0006355| regulation of transcription, DNA-dependent AHR;CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AHR;CREB1 GO:0048511| rhythmic process CREB1;AHR GO:0006366| transcription from RNA polymerase II promoter CREB1;AHR;ESR1 GO:0009636| response to toxin AHR;CES1 8817:[DB01183 DB01390] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways GO:0006811| ion transport SLCO1A2;SLC4A4;SLC4A10;SLC4A7;SLC4A5;SLC4A8 GO:0055085| transmembrane transport SLC4A4;SLCO1A2;SLC4A7;SLC4A8;ABCB1 GO:0006810| transport ABCB1;SLC4A4 GO:0002064| epithelial cell development ESR1;SLC4A5 8818:[DB01183 DB02545] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02545|Fexaramine NR1H4 common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;NR1H4;OPRK1;CREB1;TLR4 GO:0032689| negative regulation of interferon-gamma production TLR4;NR1H4 GO:0032720| negative regulation of tumor necrosis factor production TLR4;NR1H4 GO:0002376| immune system process TLR4;NR1H4 GO:0032715| negative regulation of interleukin-6 production NR1H4;TLR4 GO:0015721| bile acid and bile salt transport SLCO1A2;NR1H4;ALB GO:0034142| toll-like receptor 4 signaling pathway NR1H4;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;ESR1 GO:0045087| innate immune response TLR4;NR1H4 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;ESR1;CREB1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;NR1H4 GO:0071398| cellular response to fatty acid NR1H4;CREB1 GO:0006351| transcription, DNA-dependent ESR1;NR1H4;CREB1 GO:0043401| steroid hormone mediated signaling pathway NR1H4;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR1H4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;NR1H4 GO:0006367| transcription initiation from RNA polymerase II promoter NR1H4;ESR1 GO:0006954| inflammatory response NR1H4;TLR4 GO:0042742| defense response to bacterium NR1H4;TLR4 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1H4;CREB1 8819:[DB01183 DB03619] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes SLCO1A2 common pathways GO:0098869| GSTP1;ALB GO:0032715| negative regulation of interleukin-6 production NR1H4;TLR4 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0002376| immune system process TLR4;NR1H4 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1;NR1H4 GO:0032689| negative regulation of interferon-gamma production TLR4;NR1H4 GO:0007165| signal transduction ESR1;NR1H4;OPRD1;OPRM1;OPRK1;GPBAR1;TLR4;CREB1 GO:0015711| organic anion transport SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;GPBAR1 GO:0006810| transport ABCB11;ABCB1;SLC10A2;SLC10A1 GO:0015721| bile acid and bile salt transport ALB;SLC10A2;SLC10A1;ABCB11;SLCO1A2;NR1H4 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin GSTP1;CES1 GO:0006811| ion transport SLC10A2;SLC10A1;SLCO1A2 GO:0034142| toll-like receptor 4 signaling pathway NR1H4;TLR4 GO:0055085| transmembrane transport ABCB11;SLCO1A2;ABCB1;SLC10A1;SLC10A2 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;CES1;CYP3A4 GO:0008152| metabolic process UGT1A1;GSTP1;CES1 GO:0071398| cellular response to fatty acid CREB1;NR1H4 GO:0043066| negative regulation of apoptotic process NR1H4;GSTP1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;NR1H4 GO:0071222| cellular response to lipopolysaccharide OPRK1;GSTP1;TLR4;NR1H4 GO:0045087| innate immune response TLR4;NR1H4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;NR1H4;GSTP1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR1H4 GO:0043401| steroid hormone mediated signaling pathway NR1H4;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NR1H4;ESR1 GO:0045471| response to ethanol OPRK1;GSTP1;UGT1A1;OPRM1 GO:0016032| viral reproduction CREB1;SLC10A1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0006954| inflammatory response TLR4;NR1H4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1H4 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR1H4;ESR1 GO:0042742| defense response to bacterium TLR4;NR1H4 8820:[DB01183 DB06374] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06374|Elacestrant ESR1 common genes ESR1 common pathways GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0032355| response to estradiol stimulus ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 8821:[DB01183 DB01723] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TLR4 GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CREB1 GO:0070588| calcium ion transmembrane transport FKBP1A;OPRM1 8822:[DB01183 DB01407] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2C8 GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0042742| defense response to bacterium TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent TNF;CREB1;ESR1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0032094| response to food CYP1A1;OPRM1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;TNF GO:0042493| response to drug ABCB1;UGT1A1;CYP1A1;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;ESR1 GO:0006955| immune response TNF;TLR4;OPRK1;OPRD1 GO:0006954| inflammatory response TLR4;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TLR4 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0032729| positive regulation of interferon-gamma production TNF;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;CYP1A1;TLR4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TNF GO:0043066| negative regulation of apoptotic process NGF;ALB GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;TLR4;CREB1;ADRB2;ESR1 GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process TNF;CREB1;NGF GO:0000187| activation of MAPK activity TNF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0009636| response to toxin CYP1A1;CES1 GO:0002933| CYP1A1;CYP2C8;CYP3A4 GO:0042755| eating behavior OPRK1;ADRB3;OPRM1;OPRD1 GO:0010033| response to organic substance UGT1A1;TNF;CYP1A1;CREB1 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0010628| positive regulation of gene expression NGF;TLR4;TNF GO:1904646| ADRB2;TLR4 GO:0007568| aging ADRB3;CREB1;CYP1A1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB3;ADRB1;ADRB2;OPRD1;OPRM1 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A1;UGT1A1;CYP3A4 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;TNF GO:0007165| signal transduction ADRB2;ESR1;OPRD1;OPRM1;OPRK1;ADRB3;ADRB1;TLR4;CREB1 GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0032715| negative regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TLR4;ESR1;OPRM1 GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB 8823:[DB01183 DB01439] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes OPRM1;OPRD1;OPRK1 common pathways GO:1901381| OPRK1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0071456| cellular response to hypoxia OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0044849| OPRM1;OPRK1 GO:1990708| OPRK1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0007610| behavior OPRK1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0051881| regulation of mitochondrial membrane potential OPRD1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4 GO:0008344| adult locomotory behavior OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0042060| wound healing OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:0009314| response to radiation OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0048148| behavioral response to cocaine OPRK1 GO:1903715| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:1900745| OPRK1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1 GO:0051607| defense response to virus OPRK1 GO:0032094| response to food OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:0042711| maternal behavior OPRK1 GO:0006955| immune response OPRD1;TLR4;OPRK1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0097237| OPRD1 GO:1903937| OPRK1 GO:0032100| positive regulation of appetite OPRM1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043278| response to morphine OPRK1;OPRM1 GO:0007600| sensory perception OPRK1;OPRM1 8824:[DB01183 DB00072] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;EGFR GO:0002376| immune system process C1QA;C1S;C1QC;FCGR1A;FCGR2A;TLR4;C1R;C1QB GO:0006898| receptor-mediated endocytosis ALB;FCGR1A;FCGR2B GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0007165| signal transduction CREB1;FCGR2B;TLR4;FCGR1A;OPRK1;EGFR;ESR1;OPRM1;FCGR2C;OPRD1;ERBB2 GO:0050729| positive regulation of inflammatory response EGFR;TLR4 GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0071363| cellular response to growth factor stimulus OPRD1;ERBB2;CREB1;EGFR GO:0006468| protein phosphorylation ERBB2;EGFR;CREB1 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1;ESR1 GO:1904646| TLR4;FCGR2B GO:0010628| positive regulation of gene expression ERBB2;TLR4 GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade EGFR;TLR4;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0060065| uterus development CYP19A1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;EGFR;CREB1;TLR4 GO:0071260| cellular response to mechanical stimulus TLR4;EGFR GO:0045087| innate immune response FCGR1A;C1R;C1QB;TLR4;C1QA;C1S;C1QC GO:0042060| wound healing ERBB2;OPRM1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;ESR1;EGFR GO:0007623| circadian rhythm EGFR;CREB1 GO:0046330| positive regulation of JNK cascade TLR4;FCGR2B GO:0006351| transcription, DNA-dependent ERBB2;ESR1;CREB1 GO:0001889| liver development EGFR;UGT1A1 GO:0006955| immune response C1QC;OPRD1;FCGR2C;FCGR3A;TLR4;FCGR2B;FCGR3B;C1R;OPRK1;FCGR1A GO:0016032| viral reproduction CREB1;FCGR2B GO:0006954| inflammatory response FCGR2B;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1 GO:0006355| regulation of transcription, DNA-dependent ERBB2;ESR1;CREB1 GO:0009617| response to bacterium FCGR2B;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;CYP2C8 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 8825:[DB01183 DB07497] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways GO:0008152| metabolic process PC;CES1;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PC GO:0010629| negative regulation of gene expression ESR1;OPRD1;PC;CREB1 8826:[DB01183 DB07707] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07707|(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL ESR1;NCOA2 common genes ESR1 common pathways GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0060065| uterus development ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;TLR4;CREB1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:1903799| ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0032355| response to estradiol stimulus ESR1 8827:[DB01183 DB13146] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes ABCB1 common pathways GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport GRIN2B;GRIA3;GRIN2A;GRIN2C;GRIA4;ABCB1;SLC7A7 GO:0007613| memory CREB1;GRIN1;GRIN2A GO:1900273| CREB1;GRIN2A GO:0070588| calcium ion transmembrane transport OPRM1;GRIN3B;GRIN3A GO:0007165| signal transduction GRIA2;ESR1;OPRD1;OPRM1;OPRK1;GRIA1;TLR4;CREB1 GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1;GRIN2D;GRIN2A GO:0006811| ion transport GRIA2;GRIN2A;GRIA3;GRIN1;GRIN2D;SLCO1A2;GRIN2B;GRIN3B;GRIA1;GRIN2C;GRIA4;GRIN3A GO:0008344| adult locomotory behavior OPRD1;GRIN1;GRIN2D GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCC4;ABCB1 GO:1904646| GRIN1;GRIN2A;TLR4 GO:1903428| TLR4;GRIN1 GO:0010033| response to organic substance ABCC4;CREB1;UGT1A1 GO:1901529| ABCB1 GO:0019233| sensory perception of pain OPRK1;GRIN2A;OPRD1;GRIN1;OPRM1 GO:0045471| response to ethanol GRIN2A;GRIN2B;OPRM1;GRIN1;OPRK1;GRIN3A;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2A;GRIA2;GRIN2B;OPRM1;GRIN2D;GRIN1;GRIA3;GRIA1;GRIN3B;GRIN3A;GRIN2C;GRIA4 GO:0002576| platelet degranulation ABCC4;ALB GO:0043065| positive regulation of apoptotic process CREB1;GRIN1;GRIN2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;CREB1;TLR4 GO:0042493| response to drug ABCC4;GRIN2A;ABCB1;UGT1A1;CREB1 GO:0007268| synaptic transmission OPRK1;GRIA1;GRIN2B;OPRM1;OPRD1;GRIN2A;GRIA2 GO:0055114| oxidation-reduction process ABCC4;CYP3A4;CYP2C8 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0016032| viral reproduction SLC1A5;CREB1 GO:0008542| visual learning CREB1;GRIN1;GRIN2A GO:0043278| response to morphine GRIN1;OPRM1;OPRK1 GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 8828:[DB01183 DB07678] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07678|(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL ESR1;NCOA2 common genes ESR1 common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NCOA2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm NCOA2;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0008584| male gonad development ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;ALB GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 8829:[DB01183 DB02169] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02169|9,10-Deepithio-9,10-Didehydroacanthifolicin PPP1CC common genes common pathways GO:0042752| regulation of circadian rhythm CREB1;PPP1CC GO:0048511| rhythmic process PPP1CC;CREB1 8830:[DB01183 DB05790] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05790|SR 140333 TACR1 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;TACR1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration TACR1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway TACR1;OPRM1;OPRD1;OPRK1 GO:0032355| response to estradiol stimulus ESR1;TACR1 GO:0042755| eating behavior OPRK1;OPRD1;TACR1;OPRM1 GO:0014070| response to organic cyclic compound TACR1;UGT1A1 GO:0045471| response to ethanol OPRK1;UGT1A1;TACR1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;TACR1;OPRD1;ESR1 GO:0019233| sensory perception of pain OPRD1;TACR1;OPRM1;OPRK1 GO:0050671| positive regulation of lymphocyte proliferation TLR4;TACR1 GO:0046887| positive regulation of hormone secretion TACR1;CREB1 GO:0035094| response to nicotine TACR1;CREB1 GO:0043278| response to morphine OPRM1;TACR1;OPRK1 GO:0006954| inflammatory response TACR1;TLR4 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;TACR1 8831:[DB01183 DB01429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0032715| negative regulation of interleukin-6 production TLR4;ORM1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;ORM1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway CALM1;OPRM1;OPRD1;OPRK1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0006811| ion transport SLCO1A2;SCN5A GO:0055085| transmembrane transport SCN5A;CALM1;SLCO1A2;ABCB1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0002576| platelet degranulation CALM1;ORM1;ALB GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006954| inflammatory response ORM1;TLR4 GO:0050718| positive regulation of interleukin-1 beta secretion ORM1;TLR4 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 8832:[DB01183 DB07315] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways GO:0008152| metabolic process CES1;PYGL;UGT1A1 GO:0070266| necroptosis TLR4;PYGL 8833:[DB01183 DB00526] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0007595| lactation CREB1;ATP7B;ATP7A GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0042742| defense response to bacterium MPO;TLR4 GO:0055114| oxidation-reduction process CYP1A1;NQO1;CYP2C8;CYP1B1;SOD1;CYP3A4;CYP2E1;MPO GO:0043086| negative regulation of catalytic activity ATP7A;UGT1A1;NQO1 GO:0032094| response to food CYP1A1;MPO;OPRM1 GO:0042493| response to drug UGT1A1;CREB1;CYP1A1;ABCB1;ABCG2;ABCC2;CYP2E1;SOD1 GO:0033762| response to glucagon stimulus ABCC2;CREB1 GO:0043066| negative regulation of apoptotic process SOD1;MPO;NQO1;ALB;GSTP1 GO:0006805| xenobiotic metabolic process CYP1B1;GSTP1;CYP2C8;NQO1;CYP2E1;CYP3A4;CES1 GO:0008152| metabolic process CES1;GSTM1;UGT1A1;GSTP1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1;CYP2C8;CYP1B1 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1;ATP7A GO:0071222| cellular response to lipopolysaccharide TLR4;ABCC2;OPRK1;GSTP1 GO:0002576| platelet degranulation SOD1;ALB GO:0043065| positive regulation of apoptotic process SOD1;CYP1B1;CREB1 GO:0001889| liver development ATP7A;CYP1A1;UGT1A1 GO:0045471| response to ethanol GSTP1;OPRK1;UGT1A1;NQO1;OPRM1;CYP2E1;SOD1 GO:0071294| cellular response to zinc ion MT2A;MT1A;CREB1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0032496| response to lipopolysaccharide OPRM1;MPO;UGT1A1;TLR4;CYP1A1;ABCC2 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP2E1;CYP3A4 GO:0010033| response to organic substance SOD1;UGT1A1;CYP1A1;CREB1 GO:0008285| negative regulation of cell proliferation CYP1B1;OPRM1 GO:0007584| response to nutrient UGT1A1;NQO1 GO:0043627| response to estrogen stimulus OPRK1;ABCC2;ESR1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0000187| activation of MAPK activity SOD1;TLR4 GO:0001895| retina homeostasis SOD1;ALB GO:0055085| transmembrane transport SLC22A2;ABCC2;ABCG2;ABCB1;SLCO1A2;SLC22A3 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0006855| drug transmembrane transport SLC31A1;ABCG2;SLC22A2;ABCC2;ABCB1;SLC22A3 GO:0009636| response to toxin CES1;CYP1B1;GSTP1;CYP1A1;NQO1 GO:0014070| response to organic cyclic compound UGT1A1;NQO1;CYP1A1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0006811| ion transport SLCO1A2;SLC22A3;ATP7B;SLC31A1;SLC22A2;ATP7A GO:0015711| organic anion transport SLC22A3;SLCO1A2;SLC22A2 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A1;UGT1A1;CYP2C8 GO:0097267| CYP1A1;CYP1B1;CYP2C8 GO:0098869| GSTP1;GSTT1;ALB GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0006810| transport ABCG2;ABCC2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0007568| aging SOD1;MPO;NQO1;CYP1A1;CREB1 GO:0071456| cellular response to hypoxia OPRD1;ATP7A GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP1B1;CYP1A1;UGT1A1 GO:0036120| CREB1;ATP7A GO:0032355| response to estradiol stimulus GSTP1;NQO1;ESR1 8834:[DB01183 DB04636] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04636|Glutamine t-butyl ester QPCT common genes common pathways 8835:[DB01183 DB04676] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04676|Dansyllysine IGHA2 common genes common pathways GO:0006955| immune response TLR4;OPRK1;OPRD1;IGHA2 GO:0045087| innate immune response TLR4;IGHA2 GO:0001895| retina homeostasis IGHA2;ALB GO:0006898| receptor-mediated endocytosis ALB;IGHA2 GO:0002376| immune system process IGHA2;TLR4 8836:[DB01183 DB05254] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways GO:0032757| positive regulation of interleukin-8 production SERPINE1;TLR4 GO:0007165| signal transduction TLR4;CREB1;PLAU;OPRK1;OPRD1;OPRM1;ESR1 GO:0050729| positive regulation of inflammatory response SERPINE1;TLR4 GO:0001666| response to hypoxia PLAU;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;ESR1;TLR4;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;SERPINE1 GO:0050829| defense response to Gram-negative bacterium TLR4;SERPINE1 GO:0002576| platelet degranulation ALB;SERPINE1 GO:0007623| circadian rhythm CREB1;SERPINE1 8837:[DB01183 DB03276] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways GO:0007411| axon guidance GRB2;CREB1 GO:0007568| aging GRB2;CREB1 GO:0030154| cell differentiation CREB1;GRB2 GO:0016032| viral reproduction CREB1;GRB2 GO:0045087| innate immune response GRB2;TLR4 8838:[DB01183 DB01127] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0006351| transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0042737| drug catabolic process CYP3A4 GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0060065| uterus development ESR1;CYP19A1 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;CYP3A4;NR1I2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;NR1I2;CREB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP19A1;CYP2C8 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR1I2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP2E1 GO:0042738| exogenous drug catabolic process CYP2C8;NR1I2;CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;NR1I2;UGT1A1 GO:0007165| signal transduction OPRK1;NR1I2;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0010628| positive regulation of gene expression NR1I2;TLR4 GO:0042359| vitamin D metabolic process CYP3A4 8839:[DB01183 DB02552] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2C8;UGT1A1 GO:0016032| viral reproduction CREB1;FDPS GO:0006695| cholesterol biosynthetic process CES1;FDPS;GGPS1 GO:0006629| lipid metabolic process CYP3A4;FDPS 8840:[DB01183 DB08699] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways GO:0051924| regulation of calcium ion transport OPRD1;CAMK2G GO:0006468| protein phosphorylation CREB1;CAMK2G GO:0030154| cell differentiation CREB1;CAMK2G 8841:[DB01183 DB07916] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;CASP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CASP1 GO:0050727| regulation of inflammatory response CASP1;TLR4;ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;CASP1 GO:0042981| regulation of apoptotic process ESR1;CASP1;CREB1 GO:0071260| cellular response to mechanical stimulus TLR4;CASP1 GO:0009617| response to bacterium TLR4;CASP1 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;CASP1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CASP1;CREB1;OPRK1 GO:0001666| response to hypoxia CASP1;CREB1 8842:[DB01183 DB03800] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways GO:0009636| response to toxin CES1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0007568| aging CREB1;TYMS GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0042493| response to drug ABCB1;CREB1;TYMS;UGT1A1 GO:0045471| response to ethanol UGT1A1;TYMS;OPRK1;OPRM1 GO:0007623| circadian rhythm TYMS;CREB1 8843:[DB01183 DB03956] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways GO:0006629| lipid metabolic process PLCD1;CYP3A4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;PLCD1;OPRK1 8844:[DB01183 DB02673] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways 8845:[DB01183 DB07356] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 8846:[DB01183 DB00697] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00697|Tizanidine ADRA2A;ADRA2B;ADRA2C;NISCH;CYP1A2 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRA2C;ADRA2B;ADRA2A;OPRK1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0007165| signal transduction OPRM1;OPRD1;ADRA2C;ESR1;ADRA2B;ADRA2A;OPRK1;CREB1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0051930| regulation of sensory perception of pain OPRK1;ADRA2C;OPRM1;OPRD1 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;TLR4;UGT1A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2 8847:[DB01183 DB05052] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05052|MF101 ESR2 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1;ESR2 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;CREB1;TLR4;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 8848:[DB01183 DB06243] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06243|Eflornithine ODC1 common genes common pathways 8849:[DB01183 DB00195] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP1A2;CES1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP1A2;CYP3A4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB1;ADRB2;OPRD1;OPRM1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP1A2;CYP3A4 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;ADRB2;CREB1;TLR4;ADRB1;OPRK1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:1904646| TLR4;ADRB2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 8850:[DB01183 DB03032] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03032|S-Octylglutathione GSTM4 common genes common pathways GO:0008152| metabolic process UGT1A1;GSTM4;CES1 8851:[DB01183 DB04789] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ABCC2;OPRM1 GO:0071222| cellular response to lipopolysaccharide ABCC2;OPRK1;TLR4 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0042493| response to drug CREB1;UGT1A1;ABCC2;ABCB1 GO:0006810| transport ABCC2;ABCB1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2;SLCO1A2 GO:0043627| response to estrogen stimulus OPRK1;ABCC2;ESR1 8852:[DB01183 DB02979] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02979|N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 8853:[DB01183 DB01363] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1;OPRK1 GO:0042755| eating behavior OPRD1;OPRM1;ADRB3;OPRK1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0009636| response to toxin MAOB;SLC6A4;SLC18A2;CES1 GO:0006855| drug transmembrane transport SLC18A1;ABCB1 GO:0055085| transmembrane transport SLC18A2;SLC18A1;SLCO1A2;SLC6A4;SLC6A2;SLC6A3;ABCB1 GO:0042220| response to cocaine OPRM1;SLC6A3;OPRK1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:1904646| ADRB2;TLR4 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;ADRB3 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;OPRK1;ADRB3;ADRA2A;OPRD1;OPRM1;ADRA2B;ADRB2;ADRA2C GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007613| memory CREB1;SLC6A4 GO:0007568| aging SLC6A3;ADRB3;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0006810| transport ABCB1;SLC6A2 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0007165| signal transduction OPRM1;OPRD1;ADRA2C;ESR1;ADRA2B;ADRB2;CREB1;TLR4;ADRB1;ADRA2A;OPRK1;ADRB3 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0042493| response to drug SLC6A4;CREB1;UGT1A1;MAOB;SLC6A2;SLC6A3;ABCB1 GO:0007268| synaptic transmission SLC18A2;OPRD1;OPRM1;SLC6A2;OPRK1 GO:0055114| oxidation-reduction process CYP2C8;MAOB;MAOA;CYP3A4 GO:0007595| lactation CREB1;SLC6A3 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;MAOB;UGT1A1;TLR4 GO:0045471| response to ethanol SLC6A3;OPRK1;UGT1A1;MAOB;OPRM1 GO:0007626| locomotory behavior SLC6A3;OPRK1;SLC18A2;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 8854:[DB01183 DB04540] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;RORA;ESR1;NR1I3;VDR GO:0006805| xenobiotic metabolic process CYP3A4;CES1;RORA;CYP2C8 GO:0045087| innate immune response TLR4;CLEC4E GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;ESR1 GO:1901529| ABCB1 GO:0007623| circadian rhythm RORA;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade RORA;ESR1 GO:0006351| transcription, DNA-dependent CREB1;RORA;ESR1;NR1I3;VDR GO:0043401| steroid hormone mediated signaling pathway RORA;ESR1;NR1I3;VDR GO:0006955| immune response OPRK1;TLR4;CLEC4E;OPRD1 GO:0007595| lactation VDR;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter RORA;VDR;ESR1;NR1I3 GO:0042752| regulation of circadian rhythm CREB1;RORA GO:0060745| mammary gland branching involved in pregnancy ESR1;VDR GO:0006355| regulation of transcription, DNA-dependent VDR;NR1I3;ESR1;RORA;CREB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;RORA;CREB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042742| defense response to bacterium TLR4;CLEC4E GO:0099040| ABCB1 GO:0002376| immune system process CLEC4E;TLR4 GO:0007165| signal transduction OPRK1;CREB1;TLR4;VDR;ESR1;OPRM1;OPRD1;NR1I3 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0071456| cellular response to hypoxia RORA;OPRD1 GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0010628| positive regulation of gene expression TLR4;VDR GO:0048511| rhythmic process RORA;CREB1 GO:0008285| negative regulation of cell proliferation VDR;OPRM1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 8855:[DB01183 DB02381] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02381|nor-NOHA ARG1 common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ARG1 GO:0045087| innate immune response ARG1;TLR4 GO:0071222| cellular response to lipopolysaccharide ARG1;OPRK1;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;CREB1 GO:0001889| liver development ARG1;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;ARG1;UGT1A1;TLR4 GO:0048545| response to steroid hormone stimulus UGT1A1;ARG1 GO:0002376| immune system process TLR4;ARG1 GO:0007568| aging CREB1;ARG1 8856:[DB01183 DB14540] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes SLCO1A2;CYP2C8;ABCB1;CYP3A4 common pathways GO:0009636| response to toxin SLC22A8;CES1 GO:0014070| response to organic cyclic compound UGT1A1;ANXA1 GO:0002933| CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0006811| ion transport SLCO1A2;SLC22A8 GO:0036378| CYP3A4 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1;ABCG2 GO:0032868| response to insulin stimulus HSD11B2;OPRK1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;NR3C1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0001666| response to hypoxia CREB1;HSD11B2 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;ANXA1 GO:0008202| steroid metabolic process CYP3A7;CYP11B2;CYP11B1;CYP3A4;CYP3A5;CYP2C8;UGT1A1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;ANXA1 GO:0051384| response to glucocorticoid stimulus UGT1A1;ANXA1;HSD11B2 GO:0032355| response to estradiol stimulus ANXA1;ESR1 GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0032870| cellular response to hormone stimulus UGT1A1;CYP11B1;CYP11B2 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP3A5 GO:0002376| immune system process ANXA1;TLR4 GO:0044849| OPRM1;OPRK1;ANXA1 GO:0015711| organic anion transport SLCO1A2 GO:0007165| signal transduction OPRK1;ANXA1;TLR4;CREB1;ESR1;NR3C1;OPRD1;OPRM1 GO:0048545| response to steroid hormone stimulus UGT1A1;HSD11B2 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP2C8 GO:0032094| response to food HSD11B2;OPRM1 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR3C1;ESR1 GO:0042493| response to drug HSD11B2;ANXA1;ABCG2;ABCB1;CREB1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;CYP11B1;CYP11B2;CYP3A5;HSD11B2;HSD3B1;CYP2C8 GO:0099040| ABCB1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006955| immune response CYP11B1;OPRD1;TLR4;OPRK1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;ANXA1;NR3C1 GO:0006954| inflammatory response ANXA1;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0043066| negative regulation of apoptotic process ANXA1;ALB GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP3A4;CES1;CYP3A7 GO:0008152| metabolic process HSD3B1;UGT1A1;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;NR3C1 GO:0043065| positive regulation of apoptotic process ANXA1;CREB1 GO:0050727| regulation of inflammatory response ESR1;TLR4;ANXA1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP11B1;CYP11B2;CYP3A4 GO:0006082| organic acid metabolic process CYP2C8 GO:0045087| innate immune response TLR4;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 8857:[DB01183 DB01369] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 8858:[DB01183 DB00474] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4 GO:0097267| CYP2C19;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4 GO:0006810| transport ABCB1;GABRA1 GO:0006811| ion transport GABRA1;SLCO1A2 8859:[DB01183 DB01351] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2C8 GO:0007626| locomotory behavior OPRK1;OPRM1;CHRNA4 GO:0019233| sensory perception of pain OPRD1;OPRM1;CHRNA4;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA4;GRIA2;CHRNA7;OPRM1;GRIK2 GO:0035094| response to nicotine CHRNA4;CHRNA7;CREB1 GO:0007268| synaptic transmission GRIA2;CHRNA4;GRIK2;OPRM1;OPRD1;OPRK1;GABRA5 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2A6;CYP2C8 GO:1900273| CHRNA7;CREB1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0007165| signal transduction OPRK1;GABRA5;TLR4;CREB1;GRIA2;CHRNA4;CHRNA7;OPRD1;OPRM1;GABRA6;ESR1 GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2C8;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2A6 GO:0006810| transport GABRA5;GABRA3;ABCB1;GRIK2;GABRA6;GABRA4;GABRA1 GO:0007613| memory CREB1;CHRNA7 GO:0001666| response to hypoxia CHRNA7;CHRNA4;CREB1 GO:0006811| ion transport CHRNA7;CHRNA4;GRIA2;GABRA4;GABRA6;GRIK2;GABRA1;SLCO1A2;GABRA2;GABRA5;GABRA3 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CHRNA7;OPRM1 GO:0055085| transmembrane transport SLCO1A2;GRIK2;ABCB1 8860:[DB01183 DB07421] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;TLR4;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006351| transcription, DNA-dependent CREB1;ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;AR;ESR1;OPRM1;OPRD1 GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0016579| protein deubiquitination AR;ESR1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development AR;ESR1 8861:[DB01183 DB08173] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08173|5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways 8862:[DB01183 DB05509] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05509|LI-301 OPRM1;HTR1A common genes OPRM1 common pathways GO:0007610| behavior OPRK1;HTR1A GO:0007165| signal transduction ESR1;HTR1A;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0044849| OPRM1;OPRK1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071315| cellular response to morphine OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR1A;OPRD1;OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0007626| locomotory behavior OPRK1;OPRM1 GO:0007218| neuropeptide signaling pathway OPRK1;OPRM1;OPRD1 GO:0009314| response to radiation OPRK1;OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0033554| cellular response to stress OPRM1 GO:0042060| wound healing OPRM1 GO:0032100| positive regulation of appetite OPRM1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0043278| response to morphine OPRM1;OPRK1 GO:0007600| sensory perception OPRM1;OPRK1 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1 GO:0032094| response to food OPRM1 GO:0048149| behavioral response to ethanol OPRM1 8863:[DB01183 DB13872] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0006811| ion transport GABRG2;SLCO1A2;GABRA1;GABRA2;GABRA5;GABRA3 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;GABRA5;CREB1;TLR4;OPRK1 GO:0006810| transport GABRA5;GABRA3;ABCB1;GABRG2;GABRA1 GO:0007268| synaptic transmission GABRA5;OPRK1;OPRM1;GABRG2;OPRD1 8864:[DB01183 DB04741] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04741|Myxothiazol UQCRC1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;UQCRC1;CYP2C8 GO:0014823| response to activity UQCRC1;CREB1 8865:[DB01183 DB14503] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;SLC34A1 GO:0006810| transport ABCB1;SLC20A2;SLC20A1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;SLC20A1 GO:0006811| ion transport SLC34A2;SLC34A1;SLC34A3;SLC20A2;SLCO1A2;SLC20A1 GO:0055085| transmembrane transport SLC20A1;SLCO1A2;SLC20A2;SLC34A3;SLC34A2;ABCB1 GO:0044267| cellular protein metabolic process ALB;SLC34A2;SLC34A1 GO:0007584| response to nutrient SLC34A1;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;SLC34A2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;TLR4 GO:0042493| response to drug SLC34A1;CREB1;UGT1A1;ABCB1 GO:0016032| viral reproduction SLC20A2;CREB1 8866:[DB01183 DB05984] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05984|RAF-265 KDR;BRAF common genes common pathways GO:0007165| signal transduction BRAF;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BRAF;OPRD1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0030154| cell differentiation BRAF;KDR;CREB1 GO:0006468| protein phosphorylation CREB1;KDR;BRAF GO:0010628| positive regulation of gene expression BRAF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR;BRAF GO:0043066| negative regulation of apoptotic process BRAF;KDR;ALB GO:1990090| BRAF;CREB1 GO:0016032| viral reproduction CREB1;KDR GO:0008542| visual learning CREB1;BRAF GO:0010629| negative regulation of gene expression CREB1;KDR;OPRD1;ESR1 GO:0043491| protein kinase B signaling cascade CREB1;KDR 8867:[DB01183 DB02029] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways GO:0006954| inflammatory response EPHX2;TLR4 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0008152| metabolic process UGT1A1;EPHX2;CES1 GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4;CES1;CYP2C8 GO:0009636| response to toxin EPHX2;CES1 GO:0010628| positive regulation of gene expression EPHX2;TLR4 GO:0017144| drug metabolic process EPHX2;CYP3A4;UGT1A1;CYP2C8 8868:[DB01183 DB11601] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11601|Tuberculin Purified Protein Derivative TLR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;TLR2;CREB1 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TLR2 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR2;TLR4 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR4;TLR2 GO:0032733| positive regulation of interleukin-10 production TLR2;TLR4 GO:0045087| innate immune response TLR4;TLR2 GO:0032496| response to lipopolysaccharide OPRM1;TLR2;TLR4;UGT1A1 GO:0071223| cellular response to lipoteichoic acid TLR2;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TLR2 GO:0006954| inflammatory response TLR4;TLR2 GO:0006955| immune response OPRD1;OPRK1;TLR2;TLR4 GO:0007252| I-kappaB phosphorylation TLR4;TLR2 GO:0050707| regulation of cytokine secretion TLR2;TLR4 GO:0032760| positive regulation of tumor necrosis factor production TLR4;TLR2 GO:0002376| immune system process TLR4;TLR2 GO:0032757| positive regulation of interleukin-8 production TLR2;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR2;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;TLR2;OPRK1 GO:0032728| positive regulation of interferon-beta production TLR4;TLR2 GO:0032722| positive regulation of chemokine production TLR2;TLR4 GO:0032735| positive regulation of interleukin-12 production TLR2;TLR4 GO:0050729| positive regulation of inflammatory response TLR4;TLR2 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;TLR2 GO:0002224| toll-like receptor signaling pathway TLR2;TLR4 GO:0010628| positive regulation of gene expression TLR2;TLR4 GO:0001666| response to hypoxia TLR2;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;TLR2 GO:0009636| response to toxin TLR2;CES1 GO:0032868| response to insulin stimulus TLR2;OPRK1 8869:[DB01183 DB03896] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03896|Triphosphoric acid PAPOLA common genes common pathways 8870:[DB01183 DB06190] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06190|Solabegron ADRB3 common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;ADRB3 GO:0006898| receptor-mediated endocytosis ALB;ADRB3 GO:0007568| aging CREB1;ADRB3 GO:0007186| G-protein coupled receptor signaling pathway ADRB3;OPRK1;OPRM1;OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;ADRB3 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1;ADRB3 8871:[DB01183 DB06787] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CHRM1;CHRM2;CHRM4;OPRK1;CHRM3 GO:0007165| signal transduction ESR1;CHRM1;CHRM2;OPRM1;OPRD1;CREB1;TLR4;CHRM3;OPRK1;CHRM4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0007586| digestion UGT1A1;CHRM3 8872:[DB01183 DB03860] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0007165| signal transduction CREB1;TLR4;ESR2;OPRK1;ESR1;OPRM1;OPRD1 8873:[DB01183 DB06412] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes ALB;CYP3A4 common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug SRD5A1;CREB1;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP2C8;CYP3A4;CYP3A7;MAOA;SRD5A1;CYP3A43 GO:0008209| androgen metabolic process SRD5A1;CYP3A4;ESR1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A5;CYP3A7;CES1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;AR GO:0006629| lipid metabolic process CYP2D6;SRD5A1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0001889| liver development SRD5A1;UGT1A1 GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0042737| drug catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression TLR4;AR GO:0008584| male gonad development ESR1;SRD5A1;AR GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0016579| protein deubiquitination AR;ESR1 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0043627| response to estrogen stimulus OPRK1;ESR1;SRD5A1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0014070| response to organic cyclic compound SRD5A1;UGT1A1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0036378| CYP3A4 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;AR;TLR4;CREB1;OPRK1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB;SRD5A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A5;CYP3A7;CYP3A4;SRD5A1 GO:0032355| response to estradiol stimulus SRD5A1;ESR1 GO:0071363| cellular response to growth factor stimulus SRD5A1;OPRD1;CREB1 GO:0051659| maintenance of mitochondrion location ALB GO:0006810| transport AR;ABCB1 GO:0043069| negative regulation of programmed cell death ALB GO:0021983| pituitary gland development CREB1;SRD5A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;SRD5A1;ESR1 GO:0030154| cell differentiation SRD5A1;CREB1 8874:[DB01183 DB01228] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SCN5A GO:0006811| ion transport SLCO1A2;SCN5A GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 8875:[DB01183 DB01651] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01651|Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside APCS common genes common pathways GO:0044267| cellular protein metabolic process ALB;APCS GO:0045087| innate immune response APCS;TLR4 GO:0006953| acute-phase response UGT1A1;APCS 8876:[DB01183 DB02559] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity DHFR;ESR1 GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 8877:[DB01183 DB02222] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways GO:0006955| immune response PNP;TLR4;OPRK1;OPRD1 GO:0042493| response to drug ABCB1;UGT1A1;PNP;CREB1 8878:[DB01183 DB07111] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045087| innate immune response PPARG;TLR4 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;CREB1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0042493| response to drug UGT1A1;CREB1;PPARG;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;PPARG;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0030855| epithelial cell differentiation PPARG;CES1 8879:[DB01183 DB00707] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00707|Porfimer sodium LDLR;FCGR1A common genes common pathways GO:0006955| immune response TLR4;FCGR1A;OPRK1;OPRD1 GO:0016032| viral reproduction CREB1;LDLR GO:0010629| negative regulation of gene expression CREB1;LDLR;ESR1;OPRD1 GO:0071398| cellular response to fatty acid LDLR;CREB1 GO:0045087| innate immune response TLR4;FCGR1A GO:0006629| lipid metabolic process CYP3A4;LDLR GO:0010628| positive regulation of gene expression TLR4;LDLR GO:0006898| receptor-mediated endocytosis LDLR;FCGR1A;ALB GO:0002376| immune system process FCGR1A;TLR4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;FCGR1A GO:0050729| positive regulation of inflammatory response TLR4;LDLR GO:0008202| steroid metabolic process CYP2C8;LDLR;UGT1A1;CYP3A4 8880:[DB01183 DB06241] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06241|Clenoliximab CD4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;CD4 GO:0006955| immune response CD4;OPRD1;OPRK1;TLR4 GO:0016032| viral reproduction CD4;CREB1 GO:0051924| regulation of calcium ion transport OPRD1;CD4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD4;TLR4 GO:0050829| defense response to Gram-negative bacterium TLR4;CD4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CD4;TLR4 GO:0032355| response to estradiol stimulus CD4;ESR1 GO:0002376| immune system process TLR4;CD4 GO:0007165| signal transduction ESR1;OPRD1;CD4;OPRM1;TLR4;CREB1;OPRK1 8881:[DB01183 DB02126] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways GO:0098869| ALB;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;TLR4;ESR1;OPRM1 GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 8882:[DB01183 DB01252] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;ABCC8 GO:0032868| response to insulin stimulus OPRK1;ABCC8 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process CREB1;PPARG GO:0043627| response to estrogen stimulus ESR1;OPRK1;PPARG GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0007613| memory CREB1;ABCC8 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRM1;OPRD1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;UGT2B7 GO:0007165| signal transduction OPRD1;OPRM1;ABCC8;ESR1;OPRK1;TLR4;CREB1;PPARG GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;UGT1A3 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0008209| androgen metabolic process UGT2B7;CYP3A4;ESR1 GO:0052695| cellular glucuronidation UGT2B7;UGT1A3;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0042493| response to drug ABCC8;ABCB1;UGT1A1;CREB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A3 GO:0032760| positive regulation of tumor necrosis factor production TLR4;ABCC8 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0008542| visual learning CREB1;ABCC8 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:1904224| UGT1A1;UGT1A3 GO:0006351| transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0032496| response to lipopolysaccharide ABCC8;OPRM1;TLR4;UGT1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;UGT2B7;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;CREB1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0008152| metabolic process UGT1A1;CES1;UGT2B7;UGT1A3 8883:[DB01183 DB08214] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;NOS2 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS2 GO:0009617| response to bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0032496| response to lipopolysaccharide TLR4;NOS2;UGT1A1;OPRM1 GO:0007623| circadian rhythm CREB1;NOS2 8884:[DB01183 DB00260] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00260|Cycloserine ddlA;DDC;SLC36A2 common genes common pathways GO:0007623| circadian rhythm DDC;CREB1 GO:0006811| ion transport SLCO1A2;SLC36A2 GO:0009636| response to toxin DDC;CES1 GO:0071363| cellular response to growth factor stimulus OPRD1;DDC;CREB1 8885:[DB01183 DB01059] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes CYP3A4 common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TOP2A;CREB1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP3A7;CYP3A5;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;TLR4;CYP1A2;OPRM1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A5;CYP3A4;CYP1A2 GO:0001889| liver development CYP1A1;UGT1A1 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;CREB1;CYP1A1;UGT1A1;CYP1A2 GO:0032094| response to food OPRM1;CYP1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;CYP1A2;CYP1A1;CYP2C8;CYP3A5 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4;CYP1A2 GO:0015711| organic anion transport SLCO1A2;SLC22A5;SLC22A6 GO:0097267| CYP2C8;CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1;CYP1A1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2C8;CYP1A1;UGT1A1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB GO:0007568| aging CYP1A1;CREB1 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0048511| rhythmic process CREB1;TOP2A GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1;CREB1 GO:0006811| ion transport SLC22A5;SLCO1A2 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0009636| response to toxin CYP1A1;CES1 GO:0002933| CYP2C8;CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A5;SLCO1A2 GO:0036378| CYP3A4 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 8886:[DB01183 DB02779] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways GO:0046887| positive regulation of hormone secretion CREB1;PTPN11 GO:0071260| cellular response to mechanical stimulus TLR4;PTPN11 GO:0006629| lipid metabolic process PTPN11;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade PTPN11;TLR4;OPRM1 GO:0000187| activation of MAPK activity TLR4;PTPN11 GO:0007409| axonogenesis CREB1;PTPN11 GO:0007411| axon guidance PTPN11;CREB1 8887:[DB01183 DB08495] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08495|4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways 8888:[DB01183 DB05303] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0000187| activation of MAPK activity TNF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;OPRM1 GO:0010628| positive regulation of gene expression TNF;TLR4 GO:0010033| response to organic substance UGT1A1;TNF;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0032757| positive regulation of interleukin-8 production TNF;TLR4 GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0007165| signal transduction CREB1;TLR4;OPRK1;IL1R1;ESR1;OPRM1;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;TNF GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;TNF GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0042742| defense response to bacterium TLR4;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;ESR1 GO:0006955| immune response IL1R1;OPRK1;TLR4;TNF;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TLR4 GO:0006954| inflammatory response TNF;TLR4 GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0046330| positive regulation of JNK cascade TNF;TLR4 GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TNF GO:0050727| regulation of inflammatory response ESR1;IL1R1;TNF;TLR4 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0043065| positive regulation of apoptotic process CREB1;TNF GO:0071222| cellular response to lipopolysaccharide OPRK1;TNF;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;TNF;CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 8889:[DB01183 DB07171] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways 8890:[DB01183 DB00002] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction ESR1;FCGR2C;OPRD1;OPRM1;TLR4;FCGR2B;CREB1;OPRK1;FCGR1A;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;EGFR GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB GO:0002376| immune system process FCGR2A;FCGR1A;C1R;C1QB;TLR4;C1QA;C1QC;C1S GO:0006468| protein phosphorylation EGFR;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;EGFR;UGT1A1 GO:0050729| positive regulation of inflammatory response EGFR;TLR4 GO:0071363| cellular response to growth factor stimulus CREB1;EGFR;OPRD1 GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;EGFR GO:1904646| FCGR2B;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;EGFR GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0071260| cellular response to mechanical stimulus TLR4;EGFR GO:0045087| innate immune response C1QA;C1S;C1QC;FCGR1A;C1QB;C1R;TLR4 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;EGFR GO:0001889| liver development EGFR;UGT1A1 GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1 GO:0007623| circadian rhythm EGFR;CREB1 GO:0042060| wound healing EGFR;OPRM1 GO:0006955| immune response FCGR3A;FCGR2C;OPRD1;C1QC;C1R;FCGR3B;FCGR2B;TLR4;OPRK1;FCGR1A GO:0016032| viral reproduction CREB1;FCGR2B GO:0006954| inflammatory response FCGR2B;TLR4 GO:0009617| response to bacterium TLR4;FCGR2B GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1 8891:[DB01183 DB02701] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2D6;CYP2C8 GO:0007165| signal transduction TLR4;CREB1;OPRK1;BST1;ESR1;OPRD1;OPRM1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter PARP1;ESR1;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0014070| response to organic cyclic compound LDHA;UGT1A1 GO:0002933| CYP2C8;CYP3A4 GO:0007584| response to nutrient UGT1A1;LDHA GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043627| response to estrogen stimulus ESR1;LDHA;OPRK1 GO:0030890| positive regulation of B cell proliferation BST1;TLR4 GO:0001666| response to hypoxia LDHA;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:1904646| TLR4;PARP1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1;UGT1A1 GO:0006351| transcription, DNA-dependent ESR1;PARP1;CREB1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2D6 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PARP1;TLR4;CREB1 GO:0050727| regulation of inflammatory response ESR1;BST1;TLR4 GO:0043065| positive regulation of apoptotic process LDHA;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PARP1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CES1;CYP2D6;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process LDHA;CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1;CREB1;UGT1A1;LDHA 8892:[DB01183 DB09146] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09146|Iron saccharate HBA1;TF common genes common pathways GO:0006811| ion transport TF;SLCO1A2 GO:0044267| cellular protein metabolic process TF;ALB GO:0001895| retina homeostasis TF;ALB GO:0006898| receptor-mediated endocytosis HBA1;ALB GO:0098869| ALB;HBA1 GO:0043687| post-translational protein modification TF;ALB GO:0002576| platelet degranulation ALB;TF 8893:[DB01183 DB09449] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;TLR4 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;SLC34A1 GO:0016032| viral reproduction CREB1;SLC20A2 GO:0032355| response to estradiol stimulus ESR1;SLC34A1 GO:0006810| transport SLC20A2;SLC20A1;ABCB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;SLC20A1;ESR1;OPRD1;OPRM1 GO:0006811| ion transport SLC34A3;SLC34A1;SLC20A2;SLCO1A2;SLC20A1;SLC34A2 GO:0044267| cellular protein metabolic process SLC34A2;ALB;SLC34A1 GO:0055085| transmembrane transport SLC34A3;SLC20A2;SLCO1A2;SLC20A1;ABCB1;SLC34A2 GO:0007584| response to nutrient SLC34A1;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;SLC34A2 8894:[DB01183 DB00083] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways GO:0030154| cell differentiation CREB1;RHOB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;RHOB GO:0007268| synaptic transmission SNAP25;OPRM1;OPRD1;OPRK1 GO:0043065| positive regulation of apoptotic process CREB1;RHOB GO:0007626| locomotory behavior OPRM1;SNAP25;OPRK1 8895:[DB01183 DB02201] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 8896:[DB01183 DB07146] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways GO:0006468| protein phosphorylation LCK;CREB1 GO:0045087| innate immune response LCK;TLR4 GO:0042493| response to drug LCK;ABCB1;CREB1;UGT1A1 GO:0016032| viral reproduction LCK;CREB1 8897:[DB01183 DB07975] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation UGT1A1;DHODH GO:0007595| lactation DHODH;CREB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;DHODH GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHODH GO:0014070| response to organic cyclic compound DHODH;UGT1A1 8898:[DB01183 DB13775] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13775|Tertatolol CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 8899:[DB01183 DB08213] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0032355| response to estradiol stimulus CASP3;ESR1 GO:0001666| response to hypoxia CASP3;CREB1 GO:0010033| response to organic substance CASP3;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound CASP3;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;CREB1 GO:0042060| wound healing OPRM1;CASP3 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CASP3;OPRM1 GO:0097190| apoptotic signaling pathway CASP3;TLR4 GO:0035094| response to nicotine CREB1;CASP3 GO:0042493| response to drug CASP3;UGT1A1;CREB1;ABCB1 8900:[DB01183 DB06370] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C9;CYP3A4;CYP2E1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CYP2E1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP2C9;CYP2E1;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;UGT1A1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;UGT1A1;CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0097267| CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP2D6;CYP3A4 8901:[DB01183 DB03693] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways GO:0006468| protein phosphorylation CSNK1G2;CREB1 GO:0007165| signal transduction OPRD1;OPRM1;CSNK1G2;ESR1;TLR4;CREB1;OPRK1 8902:[DB01183 DB02624] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02624|Homoserine Lactone SLC9A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus SLC9A1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;SLC9A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;SLC9A1;ESR1 GO:0043066| negative regulation of apoptotic process SLC9A1;ALB GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC9A1 GO:0006811| ion transport SLCO1A2;SLC9A1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1;SLC9A1 GO:0014070| response to organic cyclic compound UGT1A1;SLC9A1 GO:0030154| cell differentiation SLC9A1;CREB1 GO:0071456| cellular response to hypoxia OPRD1;SLC9A1 8903:[DB01183 DB08595] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08595|4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes ESR1 common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;NCOA2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0032355| response to estradiol stimulus ESR1 8904:[DB01183 DB11348] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes ALB common pathways GO:0051924| regulation of calcium ion transport SRI;OPRD1;SLC8A1;CASR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CIB1 GO:0016032| viral reproduction CREB1;SLC20A2 GO:0043687| post-translational protein modification NUCB1;ALB GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CALR;SLC8A1;SLC34A1 GO:0007268| synaptic transmission OPRM1;NRXN1;OPRD1;CACNB2;CACNB4;CACNA1G;CACNA1E;CACNB3;CACNB1;OPRK1 GO:0006355| regulation of transcription, DNA-dependent CREB1;CALR;ESR1 GO:0045087| innate immune response S100B;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1 GO:1990090| CREB1;CIB1 GO:0042981| regulation of apoptotic process CALR;CREB1;ESR1;TPT1 GO:0002576| platelet degranulation SPARC;CALM1;ALB GO:0043065| positive regulation of apoptotic process S100B;CREB1 GO:0007626| locomotory behavior OPRM1;OPRK1;CALB1 GO:0043066| negative regulation of apoptotic process ALB;CIB1;TPT1;RGN GO:0097190| apoptotic signaling pathway TLR4;PDCD6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;CASR;OPRD1;OPRM1;ESR1 GO:0045471| response to ethanol OPRM1;SPARC;UGT1A1;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;S100A13;S100B;TLR4 GO:0051481| reduction of cytosolic calcium ion concentration SLC8A1;OPRM1;RYR3 GO:0001889| liver development UGT1A1;RGN GO:0042060| wound healing SPARC;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;SPARC GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043627| response to estrogen stimulus OPRK1;SLC34A2;ESR1 GO:0007411| axon guidance CREB1;NRXN1 GO:0007584| response to nutrient UGT1A1;SLC8A1;SLC34A1 GO:0008285| negative regulation of cell proliferation OPRM1;CIB1 GO:0010033| response to organic substance CASQ1;CALR;CREB1;UGT1A1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0001666| response to hypoxia SLC8A1;RYR1;RYR2;CREB1 GO:1904646| TLR4;CACNB1;CACNA1A GO:0010628| positive regulation of gene expression CASR;CALR;TLR4 GO:0048146| positive regulation of fibroblast proliferation S100A6;ESR1 GO:0055085| transmembrane transport TRPV5;CATSPER1;CACNA1S;CACNA1G;CACNA1E;RYR3;TRPV6;CACNA1I;ABCB1;CACNA1A;SLC34A2;CACNA1F;RYR2;CACNA1H;SLCO1A2;SLC20A1;SLC34A3;SLC8A1;CACNA1D;CACNA1C;RYR1;CALM1;SLC20A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CIB1;TLR4;OPRM1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process SLC34A2;CALB1;ALB;SLC34A1;NUCB1 GO:0006811| ion transport SLC20A1;CACNB2;SLCO1A2;CACNA1H;SLC20A2;PKD1L3;SLC34A1;CACNA1C;RYR1;CACNB4;SLC34A3;SLC8A1;CACNA1D;CACNB3;TRPV6;CACNA1E;RYR3;PKD2L1;CACNA1G;TRPV5;CACNA1S;CATSPER1;CACNB1;CACNA1F;SLC34A2;RYR2;CACNA1A;CACNA1I GO:0007409| axonogenesis S100B;S100A6;CREB1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound UGT1A1;CASR GO:0007165| signal transduction TLR4;CREB1;CACNA1I;OPRK1;SRI;OPRD1;OPRM1;ESR1;SLC20A1;S100A6;CASR;SPARC GO:0045019| negative regulation of nitric oxide biosynthetic process RGN;OPRM1 GO:0006898| receptor-mediated endocytosis CALR;ALB;SPARC GO:0070588| calcium ion transmembrane transport CACNA1A;CACNA1I;CACNA1F;RYR2;CACNB1;PKD2L1;CACNA1G;TRPV5;CATSPER1;CACNA1S;CACNA1E;RYR3;TRPV6;CACNB3;CACNB4;SLC8A1;CACNA1D;CACNA1C;RYR1;NCS1;PKD1L3;CACNA1H;OPRM1;CACNB2 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0098869| ALB GO:0035729| cellular response to hepatocyte growth factor stimulus CASR;CREB1 GO:0007613| memory CREB1;S100B GO:0030154| cell differentiation CATSPER1;CREB1;CIB1;TPT1;CALR3 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;SLC8A1;CACNA1C;CIB2;CACNA1A GO:0071456| cellular response to hypoxia SLC8A1;S100B;CASR;OPRD1 GO:0007568| aging RGN;CANX;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;CASR;OPRM1;OPRD1 GO:0006810| transport CACNA1E;CACNB3;CACNA1I;ABCB1;CACNB1;SRI;SLC20A1;CACNB4;SLC20A2 GO:0043069| negative regulation of programmed cell death ALB GO:0032355| response to estradiol stimulus CALR;SLC34A1;ESR1 GO:0051384| response to glucocorticoid stimulus S100B;SPARC;UGT1A1 GO:0071363| cellular response to growth factor stimulus CIB1;CREB1;SPARC;OPRD1 GO:0050821| protein stabilization CALR;CREB1;CHP1 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway CALM3;CALM1;CASR;OPRD1;OPRM1;OPRK1;CALM2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation CADPS2;ALB 8905:[DB01183 DB08230] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08230|5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE PIM1 common genes common pathways GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity PIM1;ESR1 GO:0006468| protein phosphorylation PIM1;CREB1 GO:0043066| negative regulation of apoptotic process ALB;PIM1 8906:[DB01183 DB12191] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12191|Obatoclax BCL2 common genes common pathways GO:0042981| regulation of apoptotic process BCL2;ESR1;CREB1 GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0009314| response to radiation OPRK1;BCL2;OPRM1 GO:0042493| response to drug BCL2;CREB1;UGT1A1;ABCB1 GO:0051607| defense response to virus OPRK1;BCL2 GO:0035094| response to nicotine BCL2;CREB1 GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0040018| positive regulation of multicellular organism growth BCL2;CREB1 GO:0071456| cellular response to hypoxia BCL2;OPRD1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;OPRD1 GO:0048545| response to steroid hormone stimulus UGT1A1;BCL2 GO:0055085| transmembrane transport SLCO1A2;BCL2;ABCB1 GO:0051881| regulation of mitochondrial membrane potential BCL2;OPRD1 GO:0009636| response to toxin CES1;BCL2 GO:0007409| axonogenesis BCL2;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;BCL2 GO:0030890| positive regulation of B cell proliferation BCL2;TLR4 GO:0008584| male gonad development ESR1;BCL2 8907:[DB01183 DB04352] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 8908:[DB01183 DB03626] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03626|5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0007568| aging CREB1;NQO1 GO:0032355| response to estradiol stimulus ESR1;NQO1 GO:0007584| response to nutrient NQO1;UGT1A1 GO:0009636| response to toxin CES1;NQO1 GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;NQO1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;NQO1 GO:0045471| response to ethanol OPRM1;OPRK1;NQO1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;NQO1;CYP3A4 GO:0043086| negative regulation of catalytic activity UGT1A1;NQO1 8909:[DB01183 DB03727] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03727|Coproporphyrin I UROD common genes common pathways 8910:[DB01183 DB00409] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00409|Remoxipride DRD2;DRD4;DRD3;HTR2A;SIGMAR1;CYP2D6 common genes common pathways GO:0007568| aging CREB1;HTR2A GO:0038003| opioid receptor signaling pathway OPRK1;SIGMAR1;OPRD1;OPRM1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory HTR2A;CREB1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway DRD2;OPRK1;DRD3;OPRM1;OPRD1;DRD4;HTR2A GO:0007610| behavior HTR2A;OPRK1 GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRK1;DRD2;TLR4;DRD3;CREB1;HTR2A;ESR1;DRD4;OPRD1;OPRM1 GO:1900273| DRD2;CREB1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0008344| adult locomotory behavior OPRD1;DRD4 GO:0042220| response to cocaine DRD3;DRD2;OPRK1;OPRM1 GO:0000187| activation of MAPK activity DRD4;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;DRD2;OPRM1;HTR2A GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0048511| rhythmic process CREB1;DRD4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0001666| response to hypoxia CREB1;DRD2 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0019233| sensory perception of pain OPRM1;OPRD1;HTR2A;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRM1;DRD2;OPRK1;UGT1A1;DRD3 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;HTR2A;OPRM1;OPRD1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;ESR1 GO:0048148| behavioral response to cocaine HTR2A;DRD4;OPRK1;DRD2;DRD3 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD3 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0007626| locomotory behavior OPRM1;OPRK1;DRD2;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;DRD2;DRD3;TLR4;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0048149| behavioral response to ethanol OPRM1;DRD4;DRD2 GO:0042493| response to drug UGT1A1;CREB1;DRD3;DRD2;ABCB1;HTR2A GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;OPRK1 GO:0035094| response to nicotine CREB1;DRD2 GO:0043278| response to morphine OPRM1;DRD3;OPRK1;DRD2 GO:0008542| visual learning DRD2;DRD3;CREB1 GO:0042752| regulation of circadian rhythm DRD4;CREB1 GO:0016032| viral reproduction CREB1;HTR2A 8911:[DB01183 DB08807] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;HTR1B GO:0042493| response to drug HTR1B;ABCB1;CREB1;UGT1A1 GO:0045471| response to ethanol UGT1A1;OPRK1;HTR1B;OPRM1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ADRB2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4;CES1 GO:0042220| response to cocaine HTR1B;OPRK1;OPRM1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1;ADRB3 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;HTR1B;OPRM1;OPRD1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:1904646| ADRB2;TLR4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;HTR1B;OPRK1 GO:0007568| aging ADRB3;CREB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;HTR1B;ADRB3;OPRK1;OPRM1;OPRD1;HTR1A;ADRB2 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007165| signal transduction CREB1;TLR4;ADRB3;OPRK1;ADRB1;HTR1B;HTR1A;ESR1;ADRB2;OPRM1;OPRD1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0007610| behavior HTR1B;OPRK1;HTR1A GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 8912:[DB01183 DB08406] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 8913:[DB01183 DB00578] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways GO:0008152| metabolic process PLA2G4A;UGT1A1;CES1 GO:0006629| lipid metabolic process CYP3A4;PLA2G4A GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB GO:0015711| organic anion transport SLC22A6;SLCO1A2 GO:0055085| transmembrane transport SLC22A6;ABCB1;SLCO1A2 8914:[DB01183 DB07708] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07708|3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes ESR1 common pathways GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm NCOA2;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NCOA2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060065| uterus development ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2 GO:0006355| regulation of transcription, DNA-dependent NCOA2;CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0002064| epithelial cell development ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 8915:[DB01183 DB05483] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05483|PCL-016 UBR4;ZFY common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ZFY;ESR1;CREB1 GO:0016032| viral reproduction CREB1;UBR4 GO:0006351| transcription, DNA-dependent CREB1;ZFY;ESR1 8916:[DB01183 DB08461] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;AR GO:0006810| transport AR;ABCB1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0016579| protein deubiquitination AR;ESR1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development ESR1;AR 8917:[DB01183 DB08751] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways GO:0007165| signal transduction ESR1;HRAS;OPRM1;OPRD1;CREB1;TLR4;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HRAS;TLR4 GO:0008285| negative regulation of cell proliferation HRAS;OPRM1 GO:0007411| axon guidance CREB1;HRAS GO:0010628| positive regulation of gene expression HRAS;TLR4 GO:0046330| positive regulation of JNK cascade TLR4;HRAS GO:0032729| positive regulation of interferon-gamma production HRAS;TLR4 GO:0042088| T-helper 1 type immune response TLR4;HRAS GO:0045944| positive regulation of transcription from RNA polymerase II promoter HRAS;ESR1;TLR4;CREB1 GO:0010629| negative regulation of gene expression CREB1;HRAS;ESR1;OPRD1 8918:[DB01183 DB07172] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;PPARG;CREB1;ESR1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0042493| response to drug ABCB1;CREB1;PPARG;UGT1A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRM1;OPRD1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;PPARG;CREB1;TLR4 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0048511| rhythmic process CREB1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 8919:[DB01183 DB01070] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01070|Dihydrotachysterol VDR common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESR1;VDR GO:0006351| transcription, DNA-dependent CREB1;VDR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;VDR;TLR4;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;ESR1 GO:0006355| regulation of transcription, DNA-dependent VDR;ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;VDR GO:0007595| lactation CREB1;VDR GO:0007165| signal transduction ESR1;OPRD1;OPRM1;VDR;TLR4;CREB1;OPRK1 GO:0010628| positive regulation of gene expression VDR;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;VDR 8920:[DB01183 DB04683] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways GO:0010628| positive regulation of gene expression NR5A1;TLR4 GO:0008584| male gonad development NR5A1;ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;NR5A1 GO:0030154| cell differentiation CREB1;NR5A1 GO:0006367| transcription initiation from RNA polymerase II promoter NR5A1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR5A1;ESR1 GO:0006355| regulation of transcription, DNA-dependent NR5A1;ESR1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR5A1;CREB1;TLR4 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR5A1 GO:0006351| transcription, DNA-dependent CREB1;NR5A1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter NR5A1;ESR1 8921:[DB01183 DB05505] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05505|NM-702 TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TBXAS1;CYP2C8 GO:0006629| lipid metabolic process TBXAS1;CYP3A4 8922:[DB01183 DB02763] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways GO:0042088| T-helper 1 type immune response IL12B;TLR4 GO:0032733| positive regulation of interleukin-10 production IL12B;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;IL12B GO:0050829| defense response to Gram-negative bacterium IL12B;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;IL12B;OPRK1 GO:0045672| positive regulation of osteoclast differentiation IL12B;CREB1 GO:0019233| sensory perception of pain OPRK1;IL12B;OPRM1;OPRD1 GO:0050671| positive regulation of lymphocyte proliferation TLR4;IL12B GO:0032729| positive regulation of interferon-gamma production TLR4;IL12B GO:0032760| positive regulation of tumor necrosis factor production IL12B;TLR4 GO:0032609| interferon-gamma production TLR4;IL12B GO:0051607| defense response to virus IL12B;OPRK1 GO:0032700| negative regulation of interleukin-17 production TLR4;IL12B GO:0050729| positive regulation of inflammatory response IL12B;TLR4 GO:0032735| positive regulation of interleukin-12 production TLR4;IL12B GO:0010033| response to organic substance UGT1A1;CREB1;IL12B 8923:[DB01183 DB08847] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08847|Hydroxyproline SLC36A1 common genes common pathways GO:0006811| ion transport SLCO1A2;SLC36A1 GO:0055085| transmembrane transport SLCO1A2;SLC36A1;ABCB1 8924:[DB01183 DB02383] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;AKR1B10;CYP2C8;CYP3A4 GO:0010033| response to organic substance AKR1B1;CREB1;UGT1A1 GO:0007586| digestion UGT1A1;AKR1B10 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;AKR1B10;AKR1B1;AKR1A1 8925:[DB01183 DB11607] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11607|Efmoroctocog alfa VWF common genes common pathways GO:0002576| platelet degranulation ALB;VWF 8926:[DB01183 DB00152] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0015711| organic anion transport SLC22A5;SLCO1A2;SLC22A2;SLC22A1 GO:0006811| ion transport SLC22A1;SLC22A2;SLCO1A2;SLC22A5 GO:0006855| drug transmembrane transport SLC22A5;SLC22A1;ABCB1;SLC22A2 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1;SLC22A5;SLCO1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP4B1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP4B1 8927:[DB01183 DB04964] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04964|Oregovomab MUC16 common genes common pathways 8928:[DB01183 DB05476] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05476|WX-UK1 PLAUR common genes common pathways GO:0043066| negative regulation of apoptotic process PLAUR;ALB GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;PLAUR 8929:[DB01183 DB04727] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04727|N-(4-{4-AMINO-6-[4-(METHYLOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-5-YL}PHENYL)-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;KDR GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0016032| viral reproduction CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0030154| cell differentiation CREB1;KDR GO:0006468| protein phosphorylation KDR;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR 8930:[DB01183 DB00097] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;FSHR;OPRM1;OPRD1;LHCGR;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;FSHR;OPRD1;OPRM1;LHCGR GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger LHCGR;OPRD1;OPRM1 GO:0008584| male gonad development LHCGR;ESR1;FSHR GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;FSHR;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;LHCGR;ESR1 8931:[DB01183 DB00210] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0010033| response to organic substance PTGS2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation RARB;PTGS2;OPRM1;RARG;RARA GO:0010628| positive regulation of gene expression RARG;RARA;TLR4 GO:1990830| RARG;CREB1 GO:0015721| bile acid and bile salt transport RXRA;ALB;SLCO1A2 GO:0008584| male gonad development RARA;ESR1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0007165| signal transduction OPRK1;RARB;CREB1;TLR4;RARA;ESR1;OPRM1;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0098869| ALB;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TLR4 GO:0032689| negative regulation of interferon-gamma production RARA;TLR4 GO:0032720| negative regulation of tumor necrosis factor production TLR4;RARA GO:0007568| aging CREB1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0006468| protein phosphorylation CREB1;RARA GO:0007613| memory PTGS2;CREB1 GO:0032355| response to estradiol stimulus RARA;PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARA;RARG;ESR1;RARB;RXRG;RXRB;RXRA GO:0016032| viral reproduction CREB1;RXRA GO:0006954| inflammatory response TLR4;PTGS2 GO:0071391| cellular response to estrogen stimulus RARA;ESR1 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent RARA;ESR1;CREB1;RXRA GO:0008361| regulation of cell size CREB1;RARG GO:0006355| regulation of transcription, DNA-dependent RARA;RARG;ESR1;RARB;RXRG;RXRA;RXRB;CREB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1;RARA GO:0042493| response to drug PTGS2;CREB1;UGT1A1;ABCB1 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0042981| regulation of apoptotic process ESR1;RARA;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;RARB;ESR1;RARG;RARA GO:0043066| negative regulation of apoptotic process RARA;RARG;PTGS2;RARB;ALB GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;RARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RARG;RARA;RXRB;RXRA;TLR4;CREB1;RXRG;RARB GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;RARB;PTGS2;RARG GO:0019233| sensory perception of pain OPRK1;OPRD1;PTGS2;OPRM1 GO:0001889| liver development UGT1A1;RARA GO:0006351| transcription, DNA-dependent ESR1;RARG;RARA;CREB1;RXRA;RXRB;RXRG;RARB GO:0043401| steroid hormone mediated signaling pathway ESR1;RARA;RARG;RXRB;RXRA;RARB;RXRG GO:0045471| response to ethanol OPRK1;UGT1A1;RARA;OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1;TLR4;UGT1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA 8932:[DB01183 DB07848] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07848|5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide F10 common genes common pathways 8933:[DB01183 DB05421] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05421|CP-122721 TACR1 common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;TACR1;OPRM1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;TACR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;TACR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1;TACR1 GO:0014070| response to organic cyclic compound UGT1A1;TACR1 GO:0042755| eating behavior OPRD1;TACR1;OPRM1;OPRK1 GO:0019233| sensory perception of pain TACR1;OPRM1;OPRD1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;TACR1;OPRM1;ESR1 GO:0045471| response to ethanol OPRM1;TACR1;UGT1A1;OPRK1 GO:0050671| positive regulation of lymphocyte proliferation TACR1;TLR4 GO:0035094| response to nicotine CREB1;TACR1 GO:0043278| response to morphine OPRK1;TACR1;OPRM1 GO:0046887| positive regulation of hormone secretion CREB1;TACR1 GO:0006954| inflammatory response TLR4;TACR1 GO:0007268| synaptic transmission OPRD1;TACR1;OPRM1;OPRK1 8934:[DB01183 DB01155] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 8935:[DB01183 DB01800] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01800|N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium ARSA common genes common pathways GO:0008152| metabolic process UGT1A1;ARSA;CES1 GO:0043687| post-translational protein modification ARSA;ALB 8936:[DB01183 DB06921] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 8937:[DB01183 DB05431] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05431|MLN-977 ALOX5 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ALOX5;CYP3A4 GO:0006954| inflammatory response TLR4;ALOX5 8938:[DB01183 DB02998] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;CREB1;TLR4;PGR;ESR1;AR GO:0006351| transcription, DNA-dependent NR3C2;PGR;CREB1;NCOA2;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway PGR;NR3C2;AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0007623| circadian rhythm NCOA2;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;NR3C2;AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;PGR;NR3C2;NCOA2;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;PGR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0007165| signal transduction CREB1;TLR4;NR3C2;OPRK1;PGR;ESR1;OPRM1;OPRD1;AR GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0006810| transport AR;ABCB1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0016579| protein deubiquitination AR;ESR1 GO:0015721| bile acid and bile salt transport NCOA2;ALB;SLCO1A2 GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression TLR4;AR GO:0030879| mammary gland development CREB1;PGR 8939:[DB01183 DB14635] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes CYP3A4;ABCB1 common pathways GO:0098869| GSTP1;GSTA1;ALB GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0031100| organ regeneration PPARG;UGT1A1;GSTP1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8;CYP2D6;CYP2C9 GO:0097267| CYP1A2;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP2C9;CYP2B6;CBR1;CYP1A2;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;VDR;PPARG;CREB1;TLR4;OPRK1 GO:0015711| organic anion transport ABCC5;SLCO1A2 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;UGT1A1;CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus GSTP1;ESR1;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1;ABCC5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression TLR4;VDR GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0008285| negative regulation of cell proliferation VDR;OPRM1;PPARG GO:0010033| response to organic substance CYP1A2;CREB1;PPARG;UGT1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0048511| rhythmic process CREB1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0002933| CYP2C8;CYP3A4 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;UGT1A1 GO:0009636| response to toxin CES1;GSTP1 GO:0030855| epithelial cell differentiation CES1;CBR1;PPARG;GSTA1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCC5;ABCB1 GO:0036378| CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2B6;CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;GSTP1;CYP2C9;CYP2B6;CYP3A4;CES1;CYP1A2 GO:0008152| metabolic process GSTM1;UGT1A1;GSTP1;GSTA1;CES1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0071222| cellular response to lipopolysaccharide OPRK1;GSTP1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;PPARG;CREB1;VDR;ESR1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;PPARG;CYP2D6 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;VDR;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;GSTP1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2D6 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;CYP1A2;OPRM1 GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR;ESR1 GO:0006351| transcription, DNA-dependent VDR;ESR1;CREB1;PPARG GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;GSTP1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0042752| regulation of circadian rhythm CREB1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1;VDR GO:0007595| lactation VDR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;VDR;ESR1 GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C8;CYP2D6;CYP3A4;CYP1A2;CBR1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0008209| androgen metabolic process CYP3A4;ESR1 8940:[DB01183 DB02813] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways GO:0044267| cellular protein metabolic process HEXB;ALB GO:0008152| metabolic process UGT1A1;CES1;HEXB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;HEXB GO:0007626| locomotory behavior OPRK1;OPRM1;HEXB 8941:[DB01183 DB04318] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways 8942:[DB01183 DB02177] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02177|1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine ITGAL common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;ITGAL;ESR1;TLR4;CREB1;OPRK1 GO:0006954| inflammatory response TLR4;ITGAL 8943:[DB01183 DB02142] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways GO:1990830| BCAT2;CREB1 GO:0008152| metabolic process CES1;UGT1A1;BCAT2 8944:[DB01183 DB12334] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12334|Milataxel TUBB1;TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 8945:[DB01183 DB06157] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways GO:0070588| calcium ion transmembrane transport ATP2A2;OPRM1 GO:0006811| ion transport ATP1A1;ATP2A2;SLCO1A2 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;ATP1A1 8946:[DB01183 DB08082] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08082|N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE MAOB common genes common pathways GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MAOB;OPRM1 GO:0045471| response to ethanol MAOB;UGT1A1;OPRK1;OPRM1 GO:0042493| response to drug MAOB;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process MAOB;CYP2C8;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0009636| response to toxin CES1;MAOB 8947:[DB01183 DB07462] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0042493| response to drug CREB1;UGT1A1;COMT;ABCB1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;COMT;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;COMT;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;COMT;OPRD1;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;COMT 8948:[DB01183 DB09303] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09303|Evolocumab PCSK9 common genes common pathways GO:0001889| liver development PCSK9;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PCSK9 GO:0043687| post-translational protein modification PCSK9;ALB GO:0008202| steroid metabolic process PCSK9;CYP3A4;CYP2C8;UGT1A1 GO:0009267| cellular response to starvation PCSK9;ALB GO:0044267| cellular protein metabolic process ALB;PCSK9 8949:[DB01183 DB01284] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01284|Tetracosactide MC2R common genes common pathways GO:0007218| neuropeptide signaling pathway OPRK1;MC2R;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;MC2R;OPRK1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;MC2R;TLR4;CREB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;MC2R 8950:[DB01183 DB03484] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03484|L-Alpha-Glycerophosphorylethanolamine ANXA5 common genes common pathways GO:0002576| platelet degranulation ANXA5;ALB GO:0043066| negative regulation of apoptotic process ALB;ANXA5 GO:0043086| negative regulation of catalytic activity ANXA5;UGT1A1 GO:0007165| signal transduction ESR1;ANXA5;OPRM1;OPRD1;CREB1;TLR4;OPRK1 GO:0010033| response to organic substance ANXA5;CREB1;UGT1A1 8951:[DB01183 DB05913] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05913|OSI-930 KIT;FLT1 common genes common pathways GO:0030154| cell differentiation FLT1;CREB1 GO:0006468| protein phosphorylation FLT1;KIT;CREB1 GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0007165| signal transduction OPRK1;CREB1;TLR4;KIT;OPRM1;OPRD1;ESR1 GO:0010863| positive regulation of phospholipase C activity KIT;ESR1;FLT1 GO:0000187| activation of MAPK activity KIT;TLR4 GO:0008584| male gonad development ESR1;KIT GO:0010628| positive regulation of gene expression KIT;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;ESR1 GO:0009314| response to radiation OPRK1;OPRM1;KIT GO:0008542| visual learning KIT;CREB1 GO:0048863| stem cell differentiation ESR1;KIT GO:0006954| inflammatory response TLR4;KIT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;ESR1 8952:[DB01183 DB04010] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04010|2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide PARP1 common genes common pathways GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:1904646| TLR4;PARP1 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:0006351| transcription, DNA-dependent CREB1;PARP1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;PARP1;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ESR1;CREB1 8953:[DB01183 DB06124] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;CAPN3;OPRK1;ESR1;OPRM1;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CAPN3 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;CAPN3 GO:0043066| negative regulation of apoptotic process CAPN3;ALB 8954:[DB01183 DB12200] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12200|Tivantinib MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ESR1;TLR4;CREB1 GO:0006468| protein phosphorylation CREB1;MET GO:0007165| signal transduction OPRM1;MET;OPRD1;ESR1;OPRK1;CREB1;TLR4 8955:[DB01183 DB06366] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06366|Pertuzumab ERBB2 common genes common pathways GO:0010628| positive regulation of gene expression ERBB2;TLR4 GO:0007165| signal transduction ERBB2;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;ERBB2 GO:0006468| protein phosphorylation ERBB2;CREB1 GO:0006355| regulation of transcription, DNA-dependent ERBB2;ESR1;CREB1 GO:0042060| wound healing OPRM1;ERBB2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;ERBB2 GO:0006351| transcription, DNA-dependent CREB1;ESR1;ERBB2 8956:[DB01183 DB04590] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways GO:0031100| organ regeneration UGT1A1;F7 GO:0032355| response to estradiol stimulus ESR1;F7 GO:0043627| response to estrogen stimulus F7;OPRK1;ESR1 GO:0001666| response to hypoxia CREB1;F7 GO:0014070| response to organic cyclic compound UGT1A1;F7 GO:0007623| circadian rhythm CREB1;F7 8957:[DB01183 DB05668] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05668|Palifosfamide DNMT1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;DNMT1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;DNMT1 GO:0010628| positive regulation of gene expression DNMT1;TLR4 8958:[DB01183 DB04758] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0032355| response to estradiol stimulus F7;ESR1 GO:0031100| organ regeneration F7;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;F7 GO:0043627| response to estrogen stimulus ESR1;OPRK1;F7 GO:0001666| response to hypoxia F7;CREB1 GO:0007623| circadian rhythm F7;CREB1 8959:[DB01183 DB05404] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05404|AZD 3355 TP53 common genes common pathways GO:0014070| response to organic cyclic compound TP53;UGT1A1 GO:0006366| transcription from RNA polymerase II promoter TP53;CREB1;ESR1 GO:0010628| positive regulation of gene expression TLR4;TP53 GO:0008285| negative regulation of cell proliferation TP53;OPRM1 GO:0016579| protein deubiquitination TP53;ESR1 GO:0048511| rhythmic process CREB1;TP53 GO:0007568| aging TP53;CREB1 GO:0071456| cellular response to hypoxia OPRD1;TP53 GO:0030154| cell differentiation CREB1;TP53 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;TP53 GO:0006355| regulation of transcription, DNA-dependent TP53;CREB1;ESR1 GO:0042493| response to drug TP53;UGT1A1;CREB1;ABCB1 GO:0016032| viral reproduction CREB1;TP53 GO:0042060| wound healing TP53;OPRM1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;TP53 GO:0045471| response to ethanol OPRK1;TP53;UGT1A1;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;TP53 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;TP53 GO:0043065| positive regulation of apoptotic process TP53;CREB1 GO:0042981| regulation of apoptotic process CREB1;TP53;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP53;ESR1 8960:[DB01183 DB06101] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways GO:0016032| viral reproduction KDR;CREB1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;KDR;CREB1 GO:0043066| negative regulation of apoptotic process FLT4;KDR;ALB GO:0046330| positive regulation of JNK cascade TLR4;FLT4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;FLT4;KDR;OPRM1 GO:0010863| positive regulation of phospholipase C activity FLT1;ESR1 GO:0030154| cell differentiation CREB1;KDR;FLT1 GO:0006468| protein phosphorylation FLT4;CREB1;KDR;FLT1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR 8961:[DB01183 DB04461] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04461|Coproporphyrinogen III UROD common genes common pathways 8962:[DB01183 DB07039] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;TLR4;CREB1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction AR;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 8963:[DB01183 DB11059] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways GO:0032868| response to insulin stimulus SLC2A1;OPRK1 GO:0055085| transmembrane transport ABCB1;SLC2A1;SLCO1A2 GO:0042908| xenobiotic transport ABCB1;SLC2A1 GO:0071260| cellular response to mechanical stimulus TLR4;SLC2A1 8964:[DB01183 DB04325] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04325|Phenethylamine PRSS2;PRSS1 common genes common pathways GO:0007586| digestion PRSS1;UGT1A1;PRSS2 8965:[DB01183 DB06973] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06973|4,4'-PROPANE-2,2-DIYLDIPHENOL ESRRG common genes common pathways GO:0006351| transcription, DNA-dependent ESRRG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESRRG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESRRG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESRRG GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESRRG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESRRG 8966:[DB01183 DB03403] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways GO:0008152| metabolic process UGT1A1;UCK2;CES1 8967:[DB01183 DB00685] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0048511| rhythmic process TOP2A;CREB1 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;TOP2A;CREB1 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0042493| response to drug CYP1A2;ABCB1;CREB1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 8968:[DB01183 DB08497] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0043065| positive regulation of apoptotic process CASP3;CREB1 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CASP3 GO:0042060| wound healing CASP3;OPRM1 GO:0097190| apoptotic signaling pathway CASP3;TLR4 GO:0035094| response to nicotine CASP3;CREB1 GO:0042493| response to drug CASP3;CREB1;UGT1A1;ABCB1 GO:0051384| response to glucocorticoid stimulus CASP3;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;CASP3 GO:0001666| response to hypoxia CREB1;CASP3 GO:0010033| response to organic substance CASP3;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;CASP3 8969:[DB01183 DB08155] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways GO:0045672| positive regulation of osteoclast differentiation CA2;CREB1 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0010033| response to organic substance CA2;CREB1;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;CA2 8970:[DB01183 DB07428] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis HBB;HBA1;ALB GO:0098869| HBB;HBA1;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;TLR4;OPRM1;ESR1 8971:[DB01183 DB04074] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:1990830| CREB1;BCAT2 GO:0055085| transmembrane transport SLC16A3;ABCB1;SLC16A7;SLCO1A2;SLC16A1 GO:0008152| metabolic process CES1;UGT1A1;BCAT2 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0032094| response to food SLC16A1;OPRM1 8972:[DB01183 DB03239] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process TTR;ALB 8973:[DB01183 DB01102] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:0042755| eating behavior OPRM1;OPRD1;ADRB3;OPRK1 GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;ADRB3;OPRK1;ADRB1 GO:0007568| aging CREB1;ADRB3 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0007165| signal transduction ADRB2;ESR1;OPRD1;OPRM1;OPRK1;ADRB3;ADRB1;TLR4;CREB1 8974:[DB01183 DB04843] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM1;OPRK1;CHRM3 GO:0007165| signal transduction OPRD1;OPRM1;CHRM1;ESR1;OPRK1;CHRM3;TLR4;CREB1 8975:[DB01183 DB07067] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 8976:[DB01183 DB05191] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05191|Atl146e ADORA2A common genes common pathways GO:0008285| negative regulation of cell proliferation ADORA2A;OPRM1 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1 GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0042755| eating behavior OPRM1;OPRD1;OPRK1;ADORA2A GO:0007165| signal transduction OPRK1;CREB1;ADORA2A;TLR4;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADORA2A;OPRD1;OPRM1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0007600| sensory perception OPRM1;ADORA2A;OPRK1 GO:0006954| inflammatory response ADORA2A;TLR4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ADORA2A;ESR1 GO:0042493| response to drug ABCB1;ADORA2A;CREB1;UGT1A1 GO:0007626| locomotory behavior OPRK1;ADORA2A;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA2A;OPRM1 8977:[DB01183 DB01834] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways GO:0045471| response to ethanol UGT1A1;GSTP1;OPRK1;OPRM1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;OPRK1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;CYP3A4;CES1 GO:0008152| metabolic process UGT1A1;GSTM1;GSTP1;CES1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0098869| ALB;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin GSTP1;CES1 8978:[DB01183 DB00859] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00859|Penicillamine SLCO1B1 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1 GO:0015711| organic anion transport SLCO1B1;SLCO1A2 GO:0006811| ion transport SLCO1B1;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;SLCO1B1;ABCB1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1A2;ALB 8979:[DB01183 DB12458] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways GO:0007268| synaptic transmission OPRM1;OPRD1;GABRG2;OPRK1 GO:1901215| GABRB3;CREB1 GO:0006811| ion transport GABRB3;GABRA1;SLCO1A2;GABRG2 GO:0006810| transport GABRG2;GABRA1;GABRB3;ABCB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;GABRB3 8980:[DB01183 DB11703] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0006351| transcription, DNA-dependent ESR1;BTK;CREB1 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0097190| apoptotic signaling pathway TLR4;BTK GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0045087| innate immune response BTK;TLR4 GO:0002755| MyD88-dependent toll-like receptor signaling pathway BTK;TLR4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP3A7;CYP2C8;CYP3A5 GO:0055114| oxidation-reduction process CYP3A43;CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent CREB1;BTK;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;BTK GO:0006468| protein phosphorylation BTK;CREB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;UGT1A1;CYP3A4;CYP3A7 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;BTK GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0002376| immune system process BTK;TLR4 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0010033| response to organic substance UGT1A1;CREB1;BTK GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 8981:[DB01183 DB00655] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes ALB;SLCO1A2;ESR1;CYP3A4;ABCB1 common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport ABCG2;ABCB1;AR GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0007568| aging CYP1A1;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR2;ESR1 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP2C8;UGT1A1;CYP1A1;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2E1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1A2;SLCO1B1;SLC22A8 GO:0045332| phospholipid translocation ABCB1 GO:0009267| cellular response to starvation ALB GO:0072089| stem cell proliferation ABCB1 GO:0051659| maintenance of mitochondrion location ALB GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0002064| epithelial cell development ESR1 GO:0015711| organic anion transport SLCO1B1;SLCO1A2 GO:0007165| signal transduction AR;ESR1;OPRM1;OPRD1;ESR2;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP2C8;CYP2B6;CYP1A1;CYP2C9;UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C8;CYP1A2;CYP4A11 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0098869| ALB GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:1903799| ESR1 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2C8;CYP3A4;CYP1A2 GO:0006898| receptor-mediated endocytosis ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0036378| CYP3A4 GO:0055085| transmembrane transport SLCO2B1;ABCG2;ABCB1;SLCO1B1;SLC22A8;SLCO1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0009636| response to toxin CES1;SLC22A8;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;CYP1A2 GO:0002933| CYP3A4;CYP1A1;CYP2C8;CYP3A5 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SLCO2B1;SLCO1B1;SLC22A8;SLCO1A2 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination AR;ESR1 GO:0010033| response to organic substance UGT1A1;CYP1A1;CREB1;CYP1A2 GO:0008285| negative regulation of cell proliferation AR;OPRM1;CYP1B1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1B1;SLCO1A2 GO:0008584| male gonad development ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;ESR2;CREB1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1;ESR2 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP3A4;CYP1A2 GO:0045471| response to ethanol OPRM1;CYP2E1;UGT1A1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;OPRK1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A1;OPRM1;CYP1A2 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;CYP1A2 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR;ESR2 GO:0043066| negative regulation of apoptotic process ALB GO:0060065| uterus development ESR1;CYP19A1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CES1;CYP2C9;CYP2B6;CYP1B1;CYP3A5;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP4A11;CYP2B6;CYP1A1;CYP2C9;CYP2C8;CYP1B1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TLR4;CREB1;AR;ESR1 GO:0002576| platelet degranulation ALB GO:0043065| positive regulation of apoptotic process CREB1;CYP1B1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:2001225| regulation of chloride transport ABCB1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP4A11;CYP2B6;CYP19A1;CYP1A1;CYP2C9;CYP2C8;CYP3A5;CYP1B1 GO:0099040| ABCB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;ESR2;CREB1 GO:0032094| response to food CYP1A1;OPRM1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1;ESR2 GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;CREB1;UGT1A1;CYP2E1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8;CYP2B6;CYP2C9 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;AR;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 8982:[DB01183 DB00902] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00902|Methdilazine HRH1 common genes common pathways GO:0006954| inflammatory response TLR4;HRH1 GO:0008542| visual learning HRH1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;HRH1;OPRD1;OPRM1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;HRH1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HRH1;OPRD1;OPRK1 GO:0007613| memory CREB1;HRH1 8983:[DB01183 DB05087] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0006811| ion transport SLCO1A2;GABRA6;GABRA4;GABRA1;GABRA2;GABRA3;GABRA5 GO:0006810| transport GABRA1;GABRA6;GABRA4;GABRA5;GABRA3;ABCB1 GO:0007165| signal transduction GABRA5;TLR4;CREB1;OPRK1;OPRD1;OPRM1;GABRA6;ESR1 GO:0007268| synaptic transmission GABRA5;OPRK1;OPRM1;OPRD1 8984:[DB01183 DB04840] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes ABCB1 common pathways GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2D6;CYP2C8 GO:0099040| ABCB1 GO:0032094| response to food CYP1A1;OPRM1 GO:0042493| response to drug SLC6A2;UGT1A1;CYP1A1;CREB1;ABCB1 GO:0007268| synaptic transmission OPRM1;OPRD1;SLC6A2;OPRK1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1;CYP2D6 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;TLR4;OPRM1 GO:0010033| response to organic substance CREB1;CYP1A1;UGT1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLCO1A2 GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0009636| response to toxin CYP1A1;CES1 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A1;UGT1A1;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0042908| xenobiotic transport ABCB1 GO:0007568| aging CYP1A1;CREB1 GO:0006810| transport ABCB1;SLC6A2 GO:0045332| phospholipid translocation ABCB1 GO:0008202| steroid metabolic process CYP1A1;UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 8985:[DB01183 DB04562] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04562|Tricarballylic Acid ACO2 common genes common pathways GO:0001889| liver development ACO2;UGT1A1 GO:0008152| metabolic process CES1;UGT1A1;ACO2 8986:[DB01183 DB00886] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00886|Omapatrilat ACE;MME common genes common pathways GO:0019233| sensory perception of pain OPRK1;MME;OPRM1;OPRD1 8987:[DB01183 DB01626] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01626|Pargyline MAOB;MAOA common genes common pathways GO:0045471| response to ethanol OPRM1;OPRK1;MAOB;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;MAOB;UGT1A1;TLR4 GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8;MAOB GO:0042493| response to drug ABCB1;UGT1A1;MAOB;CREB1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0009636| response to toxin CES1;MAOB 8988:[DB01183 DB14642] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway AVPR2;OPRK1;AVPR1B;OPRM1;OPRD1;AVPR1A GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;AVPR1A;AVPR1B GO:0006810| transport ABCC2;ABCB1 GO:0032870| cellular response to hormone stimulus AVPR1A;UGT1A1;AVPR1B;ABCC2;AVPR2 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;AVPR2 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0007165| signal transduction TLR4;CREB1;AVPR1B;OPRK1;AVPR2;ESR1;AVPR1A;OPRD1;OPRM1 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport SLCO1A2;ABCC2;ABCB1 GO:0010628| positive regulation of gene expression AVPR2;TLR4 GO:0043627| response to estrogen stimulus ABCC2;OPRK1;ESR1 GO:0010033| response to organic substance UGT1A1;CREB1;AVPR1A GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ABCC2;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;ABCC2;OPRK1 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0042493| response to drug CREB1;UGT1A1;ABCC2;ABCB1 GO:0042711| maternal behavior AVPR1A;OPRK1 GO:0032609| interferon-gamma production TLR4;AVPR2 8989:[DB01183 DB04865] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 8990:[DB01183 DB06536] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction TLR4;PPARG;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0001666| response to hypoxia PPARA;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0048511| rhythmic process PPARA;CREB1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;PPARG;CREB1;ESR1;PPARA GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARA;CYP3A4;PPARG GO:0042060| wound healing OPRM1;PPARA GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1;PPARA GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1;PPARA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARA;CREB1;PPARG GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARA;PPARG;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;ESR1;PPARG;CREB1 GO:1901215| CREB1;PPARA 8991:[DB01183 DB08760] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRM1;OPRD1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;PPARG;OPRK1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0030855| epithelial cell differentiation CES1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process PPARG;CREB1 GO:0010033| response to organic substance PPARG;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CREB1;TLR4;ESR1 GO:0045087| innate immune response PPARG;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 8992:[DB01183 DB12945] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 8993:[DB01183 DB04889] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0001666| response to hypoxia DRD2;CREB1;SLC6A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4 GO:0007409| axonogenesis DRD2;CREB1 GO:0009636| response to toxin SLC6A4;CES1;DRD2;MAOB GO:0055085| transmembrane transport SLC6A4;SLCO1A2;ABCB1;SLC6A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;DRD2 GO:0042220| response to cocaine OPRK1;DRD2;OPRM1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:1900273| CREB1;DRD2 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0007165| signal transduction OPRD1;OPRM1;ESR1;DRD2;OPRK1;TLR4;CREB1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;DRD2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0007613| memory SLC6A4;CREB1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0006810| transport SLC6A2;ABCB1 GO:0043278| response to morphine DRD2;OPRK1;OPRM1 GO:0008542| visual learning CREB1;DRD2 GO:0035094| response to nicotine CREB1;DRD2 GO:0042493| response to drug CREB1;SLC6A2;UGT1A1;MAOB;DRD2;ABCB1;SLC6A4 GO:0007268| synaptic transmission SLC6A2;OPRK1;OPRD1;OPRM1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0055114| oxidation-reduction process MAOB;CYP2D6;CYP2C8;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;CREB1;TLR4;ESR1 GO:0007626| locomotory behavior OPRM1;OPRK1;DRD2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CES1;CYP3A4 GO:0048148| behavioral response to cocaine DRD2;OPRK1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0032496| response to lipopolysaccharide OPRM1;MAOB;UGT1A1;TLR4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0045471| response to ethanol DRD2;OPRK1;UGT1A1;MAOB;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 8994:[DB01183 DB04872] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04872|Osanetant TACR3 common genes common pathways GO:0043278| response to morphine OPRK1;OPRM1;TACR3 GO:0042220| response to cocaine TACR3;OPRM1;OPRK1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;TACR3;CREB1;TLR4;OPRK1 GO:0032355| response to estradiol stimulus TACR3;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;TACR3;OPRD1;OPRM1 GO:0007568| aging CREB1;TACR3 8995:[DB01183 DB04187] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;GSTM1 8996:[DB01183 DB01569] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01569|Formebolone HSD11B2 common genes common pathways GO:0051384| response to glucocorticoid stimulus HSD11B2;UGT1A1 GO:0048545| response to steroid hormone stimulus HSD11B2;UGT1A1 GO:0032868| response to insulin stimulus HSD11B2;OPRK1 GO:0001666| response to hypoxia CREB1;HSD11B2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;HSD11B2 GO:0042493| response to drug ABCB1;HSD11B2;UGT1A1;CREB1 GO:0032094| response to food OPRM1;HSD11B2 8997:[DB01183 DB05434] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0001666| response to hypoxia CREB1;VEGFA GO:0010628| positive regulation of gene expression TLR4;VEGFA GO:0008285| negative regulation of cell proliferation CXCL8;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF2;VEGFA;OPRM1;TLR4 GO:0000187| activation of MAPK activity FGF2;TLR4;HGF GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0031100| organ regeneration HGF;UGT1A1 GO:0010863| positive regulation of phospholipase C activity ESR1;FGF2 GO:0035729| cellular response to hepatocyte growth factor stimulus HGF;CREB1 GO:0032715| negative regulation of interleukin-6 production HGF;TLR4 GO:0007165| signal transduction OPRK1;CXCL8;CREB1;TLR4;ESR1;FGF2;OPRM1;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;OPRD1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0072089| stem cell proliferation FGF2;ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CXCL8;OPRM1;OPRD1 GO:0030154| cell differentiation CREB1;VEGFA;FGF2 GO:0071456| cellular response to hypoxia OPRD1;VEGFA GO:0006954| inflammatory response CXCL8;TLR4 GO:0006955| immune response OPRK1;CXCL8;TLR4;OPRD1 GO:0007595| lactation CREB1;VEGFA GO:0010629| negative regulation of gene expression CREB1;ESR1;VEGFA;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;ESR1;CREB1 GO:0002576| platelet degranulation VEGFA;HGF;ALB GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;CXCL8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;VEGFA;ESR1;HGF;CREB1;TLR4 GO:0043066| negative regulation of apoptotic process VEGFA;HGF;ALB GO:0032733| positive regulation of interleukin-10 production HGF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0060749| mammary gland alveolus development VEGFA;ESR1 GO:1900745| VEGFA;OPRK1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0042060| wound healing OPRM1;FGF2 GO:0001889| liver development UGT1A1;HGF 8998:[DB01183 DB06731] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06731|Seproxetine CYP3A5;CYP3A7;CYP2C9;CYP2C19 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2C19;CYP2C9;CYP3A4;CYP3A7 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP3A5;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CES1;CYP3A5;CYP2C19;CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;CYP2C9;UGT1A1;CYP3A4;CYP3A7 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2C8;CYP3A4 GO:0097267| CYP2C19;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C19;CYP2C8 8999:[DB01183 DB00517] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRM1;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;CHRM2;ESR1;CHRM1;OPRK1;CHRM3;TLR4;CREB1 GO:0007186| G-protein coupled receptor signaling pathway CHRM1;CHRM2;OPRM1;OPRD1;OPRK1;CHRM3 9000:[DB01183 DB00131] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes CREB1 common pathways GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 GO:0010033| response to organic substance AMPD1;ACSL1;UGT1A1;CREB1 GO:0014823| response to activity CREB1;PRKAA1 GO:1902065| CREB1 GO:0007411| axon guidance CREB1 GO:0007584| response to nutrient UGT1A1;ACSL1 GO:0048511| rhythmic process CREB1;PRKAA1;ADCY1 GO:0010628| positive regulation of gene expression PRKAB1;PRKAA1;TLR4 GO:0001666| response to hypoxia CREB1;PRKAA1 GO:0045600| positive regulation of fat cell differentiation CREB1 GO:1990830| CREB1 GO:0000187| activation of MAPK activity TLR4;PRKAA1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0060430| lung saccule development CREB1 GO:0014070| response to organic cyclic compound ACSL1;UGT1A1 GO:0007409| axonogenesis CREB1;ADCY1 GO:0030879| mammary gland development CREB1 GO:0007165| signal transduction OPRD1;PDE4D;OPRM1;ESR1;HINT1;PRKAB1;PRKAB2;TLR4;CREB1;ADCY1;PRKAA1;OPRK1;PDE4B GO:0032916| positive regulation of transforming growth factor beta3 production CREB1 GO:0048145| regulation of fibroblast proliferation CREB1 GO:1900273| CREB1 GO:0035729| cellular response to hepatocyte growth factor stimulus CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1 GO:0007568| aging PDE4D;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADCY1;OPRK1 GO:1990314| CREB1 GO:0030154| cell differentiation CREB1 GO:0007613| memory CREB1 GO:0021983| pituitary gland development CREB1 GO:0006468| protein phosphorylation PIM1;PRKAB2;PRKAB1;CREB1;PRKAA1 GO:0071456| cellular response to hypoxia PRKAA1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;PRKAA1;CYP2C8 GO:0036120| CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE4B;ADCY1;PDE4D;OPRD1;OPRM1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1 GO:0050821| protein stabilization CREB1 GO:0008542| visual learning CREB1 GO:0035094| response to nicotine CREB1 GO:0010944| negative regulation of transcription by competitive promoter binding CREB1 GO:0033363| secretory granule organization CREB1 GO:0060509| Type I pneumocyte differentiation CREB1 GO:0042752| regulation of circadian rhythm CREB1;PRKAA1;ADCY1 GO:0046887| positive regulation of hormone secretion CREB1 GO:0007595| lactation CREB1;APRT GO:0016032| viral reproduction CREB1 GO:1901215| CREB1 GO:0043491| protein kinase B signaling cascade CREB1 GO:0008361| regulation of cell size CREB1 GO:2000505| regulation of energy homeostasis OPRK1;PRKAA1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0042493| response to drug CREB1;UGT1A1;ACSL1;ABCB1;ADCY1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;HINT1;CREB1;PRKAA1 GO:0060251| regulation of glial cell proliferation CREB1 GO:0071361| cellular response to ethanol PRKAA1;UGT1A1 GO:0006629| lipid metabolic process PRKAA1;ACSL1;CYP3A4;PRKAB2;PRKAB1 GO:0033762| response to glucagon stimulus CREB1 GO:0060428| lung epithelium development CREB1 GO:1990090| CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;FBP1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0070266| necroptosis TLR4;PYGL GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0008152| metabolic process PYGL;ACSS2;ACSS1;UGT1A1;ACSL1;CES1;FBP1 GO:0071398| cellular response to fatty acid CREB1 GO:0055025| positive regulation of cardiac muscle tissue development CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1 GO:0043066| negative regulation of apoptotic process PIM1;ALB;PRKAA1 GO:0043065| positive regulation of apoptotic process CREB1 GO:0045672| positive regulation of osteoclast differentiation CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4 GO:0071222| cellular response to lipopolysaccharide PDE4D;TLR4;PDE4B;OPRK1 GO:0006695| cholesterol biosynthetic process PRKAA1;CES1 GO:0006351| transcription, DNA-dependent PRKAA1;CREB1;ESR1;HINT1 GO:0034670| chemotaxis to arachidonic acid CREB1 GO:0046889| positive regulation of lipid biosynthetic process CREB1 GO:0032729| positive regulation of interferon-gamma production PDE4D;PDE4B;TLR4 GO:0071294| cellular response to zinc ion CREB1 GO:0007623| circadian rhythm ADCY1;CREB1 9001:[DB01183 DB03059] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03059|Acetoacetyl-CoA HADH;ACADS;ECHS1 common genes common pathways GO:0008152| metabolic process UGT1A1;ECHS1;CES1;ACADS GO:0006629| lipid metabolic process ECHS1;ACADS;CYP3A4;HADH GO:0042493| response to drug ABCB1;UGT1A1;CREB1;HADH GO:0055114| oxidation-reduction process ACADS;CYP3A4;HADH;CYP2C8 GO:0014823| response to activity CREB1;HADH GO:0032868| response to insulin stimulus HADH;OPRK1 9002:[DB01183 DB04066] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;PTGR1;CYP3A4 9003:[DB01183 DB09282] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;PDE5A GO:0007165| signal transduction PDE5A;CREB1;TLR4;GUCY1A2;OPRK1;OPRM1;OPRD1;ESR1 9004:[DB01183 DB00630] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0016032| viral reproduction FDPS;CREB1 GO:0006695| cholesterol biosynthetic process FDPS;CES1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006811| ion transport ATP6V1A;SLCO1A2 GO:0006810| transport ABCB1;ATP6V1A GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2C8;UGT1A1 9005:[DB01183 DB06098] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06098|PRLX 93936 VDAC2;VDAC3 common genes common pathways GO:0007268| synaptic transmission VDAC3;OPRM1;OPRD1;OPRK1 GO:0006811| ion transport SLCO1A2;VDAC2;VDAC3 GO:0055085| transmembrane transport SLCO1A2;VDAC3;VDAC2;ABCB1 9006:[DB01183 DB08326] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways GO:0051384| response to glucocorticoid stimulus ACSBG1;UGT1A1 GO:0008152| metabolic process ACSBG1;CES1;UGT1A1 GO:0006629| lipid metabolic process ACSBG1;CYP3A4 9007:[DB01183 DB08846] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCB;TLR4 GO:0006954| inflammatory response TLR4;SYK GO:0016032| viral reproduction CREB1;SYK GO:0042742| defense response to bacterium TLR4;SYK GO:2001225| regulation of chloride transport CA7;CA2;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A1;SQLE;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;CA9;UGT1A1;CREB1;CYP1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PRKCB;CSNK2A1;ESR1 GO:0032094| response to food OPRM1;CYP1A1 GO:0045087| innate immune response SYK;TLR4 GO:0045672| positive regulation of osteoclast differentiation CA2;CREB1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2E1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8;CYP2E1 GO:0045471| response to ethanol CA3;CYP2E1;OPRM1;UGT1A1;OPRK1 GO:0097190| apoptotic signaling pathway TLR4;PRKCA GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PRKCB;TLR4 GO:0006695| cholesterol biosynthetic process SQLE;CES1 GO:0006351| transcription, DNA-dependent PRKCB;ESR1;CSNK2A1;CREB1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2E1;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A1;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0043627| response to estrogen stimulus CA2;OPRK1;ESR1 GO:0007411| axon guidance CREB1;PRKCA GO:0048511| rhythmic process CSNK2A1;CREB1 GO:0010033| response to organic substance SQLE;CREB1;CYP1A1;UGT1A1;CA2 GO:0001666| response to hypoxia CA9;PRKCB;CYP1A1;CREB1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA GO:0055085| transmembrane transport SLC22A6;ABCB1;SLCO1A2;SLC22A11 GO:0070374| positive regulation of ERK1 and ERK2 cascade PRKCA;TLR4;OPRM1 GO:0000187| activation of MAPK activity SYK;TLR4 GO:0006811| ion transport SLC22A11;SLCO1A2 GO:0002933| CYP3A4;CYP2C8;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0009636| response to toxin CES1;CYP1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;PRKCB;ESR1;OPRM1;CSNK2A1;OPRD1 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP2C8;CYP2E1;CYP3A4 GO:0015711| organic anion transport SLC22A6;SLC22A11;SLCO1A2 GO:0002376| immune system process PRKCB;TLR4;SYK GO:0006468| protein phosphorylation PRKCA;CREB1;SYK;PRKCB;PRKACA;CSNK2A1 GO:0007568| aging CYP1A1;CREB1 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1A2;SLC22A11 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP1A1;UGT1A1 9008:[DB01183 DB03349] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide TLR4;PDE4B;OPRK1 GO:0032729| positive regulation of interferon-gamma production PDE4B;TLR4 GO:0006351| transcription, DNA-dependent CREB1;HINT1;ESR1 GO:0006355| regulation of transcription, DNA-dependent HINT1;ESR1;CREB1 GO:0007165| signal transduction HINT1;ESR1;OPRM1;OPRD1;CREB1;TLR4;PDE4B;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PDE4B;OPRK1 9009:[DB01183 DB02872] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways GO:0043491| protein kinase B signaling cascade MDM2;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;MDM2 GO:0042493| response to drug ABCB1;MDM2;UGT1A1;CREB1 GO:0043278| response to morphine MDM2;OPRK1;OPRM1 GO:0016032| viral reproduction MDM2;CREB1 GO:0071391| cellular response to estrogen stimulus MDM2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MDM2;ESR1 GO:0043066| negative regulation of apoptotic process MDM2;ALB GO:0042220| response to cocaine OPRM1;MDM2;OPRK1 GO:0009636| response to toxin MDM2;CES1 GO:0016579| protein deubiquitination MDM2;ESR1 GO:0010628| positive regulation of gene expression TLR4;MDM2 GO:0071456| cellular response to hypoxia MDM2;OPRD1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;MDM2 GO:0048545| response to steroid hormone stimulus UGT1A1;MDM2 9010:[DB01183 DB08822] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08822|Azilsartan medoxomil AGTR1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;AGTR1 GO:0050729| positive regulation of inflammatory response TLR4;AGTR1 GO:0007186| G-protein coupled receptor signaling pathway AGTR1;OPRD1;OPRM1;OPRK1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;AGTR1;OPRM1;OPRD1;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1;AGTR1 GO:0050727| regulation of inflammatory response TLR4;AGTR1;ESR1 9011:[DB01183 DB05418] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05418|GW 597599 TACR1 common genes common pathways GO:0042755| eating behavior OPRK1;OPRD1;TACR1;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;TACR1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TACR1;OPRK1;TLR4;CREB1 GO:0032355| response to estradiol stimulus TACR1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;TACR1;OPRD1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;TACR1;ESR1 GO:0006954| inflammatory response TLR4;TACR1 GO:0046887| positive regulation of hormone secretion TACR1;CREB1 GO:0043278| response to morphine OPRK1;OPRM1;TACR1 GO:0035094| response to nicotine TACR1;CREB1 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;TACR1 GO:0050671| positive regulation of lymphocyte proliferation TACR1;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1;TACR1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;TACR1 GO:0019233| sensory perception of pain OPRM1;TACR1;OPRD1;OPRK1 9012:[DB01183 DB01080] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0035094| response to nicotine ABAT;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABAT;ABCB1 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0007626| locomotory behavior OPRM1;OPRK1;ABAT GO:0048148| behavioral response to cocaine OPRK1;ABAT GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CES1;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0045471| response to ethanol OPRK1;ABAT;UGT1A1;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity GABBR1;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0001666| response to hypoxia CREB1;ABAT GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC36A1 GO:0042220| response to cocaine ABAT;OPRK1;OPRM1 GO:0006811| ion transport SLC36A1;SLCO1A2 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2C8;CYP3A4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;GABBR1;OPRM1;ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0007568| aging ABAT;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1;GABBR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;GABBR1;OPRD1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 9013:[DB01183 DB05218] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05218|PN0621 TNF common genes common pathways GO:0006954| inflammatory response TNF;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TLR4 GO:0006955| immune response OPRD1;OPRK1;TNF;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF GO:0010629| negative regulation of gene expression TNF;CREB1;ESR1;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;TNF;CREB1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0042742| defense response to bacterium TNF;TLR4 GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;TNF;CREB1;ESR1 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;OPRK1 GO:0043065| positive regulation of apoptotic process TNF;CREB1 GO:0050727| regulation of inflammatory response TLR4;TNF;ESR1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TNF GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TNF GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0046330| positive regulation of JNK cascade TNF;TLR4 GO:0010628| positive regulation of gene expression TLR4;TNF GO:0010033| response to organic substance UGT1A1;TNF;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;TNF GO:0000187| activation of MAPK activity TNF;TLR4 GO:0032757| positive regulation of interleukin-8 production TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032715| negative regulation of interleukin-6 production TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TLR4;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0032722| positive regulation of chemokine production TNF;TLR4 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 9014:[DB01183 DB07976] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;DHODH GO:0007595| lactation CREB1;DHODH GO:0042594| response to starvation DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;DHODH GO:0014070| response to organic cyclic compound DHODH;UGT1A1 9015:[DB01183 DB02499] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02499|Dinor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0001889| liver development ARG1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ARG1;OPRM1 GO:0045087| innate immune response ARG1;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;ARG1 GO:0042493| response to drug ARG1;ABCB1;CREB1;UGT1A1 GO:0007568| aging ARG1;CREB1 GO:0048545| response to steroid hormone stimulus ARG1;UGT1A1 GO:0002376| immune system process ARG1;TLR4 9016:[DB01183 DB02109] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02109|Hadacidin purA;ADSSL1 common genes common pathways GO:0002376| immune system process TLR4;ADSSL1 GO:0042594| response to starvation UGT1A1;ADSSL1 9017:[DB01183 DB03415] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ACADM;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;ACADM GO:0051791| medium-chain fatty acid metabolic process CES1;ACADM GO:0008152| metabolic process CES1;ACADM;UGT1A1 9018:[DB01183 DB06999] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;BRAF;TLR4 GO:0010628| positive regulation of gene expression BRAF;TLR4 GO:0006468| protein phosphorylation CREB1;BRAF GO:0030154| cell differentiation BRAF;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;BRAF;OPRK1;CREB1;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BRAF GO:0008542| visual learning BRAF;CREB1 GO:0043066| negative regulation of apoptotic process BRAF;ALB GO:1990090| CREB1;BRAF 9019:[DB01183 DB07435] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07435|1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE POLK;polA common genes common pathways 9020:[DB01183 DB00405] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00405|Dexbrompheniramine HRH1 common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;HRH1;OPRD1;CREB1;TLR4;OPRK1 GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;HRH1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;HRH1;OPRD1;ESR1 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response HRH1;TLR4 9021:[DB01183 DB04883] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04883|Darusentan EDNRA common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;EDNRA;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1;EDNRA GO:0007165| signal transduction OPRK1;EDNRA;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0001666| response to hypoxia EDNRA;CREB1 9022:[DB01183 DB00878] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00878|Chlorhexidine HNMT;cat common genes common pathways 9023:[DB01183 DB07621] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP2C8;UGT1A1 9024:[DB01183 DB11429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11429|Mibolerone AR common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;AR GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;AR;TLR4;CREB1;OPRK1 GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression TLR4;AR 9025:[DB01183 DB05466] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05466|R673 TACR1 common genes common pathways GO:0006954| inflammatory response TACR1;TLR4 GO:0043278| response to morphine OPRM1;TACR1;OPRK1 GO:0035094| response to nicotine TACR1;CREB1 GO:0046887| positive regulation of hormone secretion TACR1;CREB1 GO:0007268| synaptic transmission OPRD1;TACR1;OPRM1;OPRK1 GO:0050671| positive regulation of lymphocyte proliferation TACR1;TLR4 GO:0019233| sensory perception of pain OPRM1;TACR1;OPRD1;OPRK1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;TACR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;TACR1;OPRK1 GO:0014070| response to organic cyclic compound UGT1A1;TACR1 GO:0042755| eating behavior OPRK1;OPRD1;TACR1;OPRM1 GO:0007165| signal transduction ESR1;OPRD1;TACR1;OPRM1;OPRK1;TLR4;CREB1 GO:0032355| response to estradiol stimulus TACR1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;TACR1;OPRD1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;TACR1;OPRM1 9026:[DB01183 DB05752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0007165| signal transduction CREB1;TLR4;CHRM3;OPRK1;CHRM4;ESR1;CHRM1;CHRM2;CHRM5;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CHRM1;CHRM2;OPRM1;CHRM5;OPRD1;CHRM3;OPRK1;CHRM4 GO:0007586| digestion UGT1A1;CHRM3 9027:[DB01183 DB07804] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07804|5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE F10 common genes common pathways 9028:[DB01183 DB04805] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04805|Virginiamycin S1 RPL37 common genes common pathways 9029:[DB01183 DB06460] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1;EDNRB GO:0014070| response to organic cyclic compound UGT1A1;EDNRB GO:0001666| response to hypoxia EDNRA;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration EDNRB;EDNRA;ESR1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;EDNRA;OPRK1 GO:0007568| aging EDNRB;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;EDNRB;EDNRA;OPRD1;OPRM1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;EDNRB;CREB1;EDNRA;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger EDNRB;OPRK1;OPRM1;OPRD1;ESR1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1;EDNRB GO:0032496| response to lipopolysaccharide OPRM1;EDNRB;UGT1A1;TLR4 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;EDNRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;EDNRB GO:0071222| cellular response to lipopolysaccharide OPRK1;EDNRB;TLR4 GO:0043066| negative regulation of apoptotic process ALB;EDNRB 9030:[DB01183 DB01019] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway CHRM2;CHRM1;OPRD1;OPRM1;OPRK1;CHRM4;CHRM3 GO:0007165| signal transduction CREB1;TLR4;CHRM3;OPRK1;CHRM4;ESR1;CHRM1;CHRM2;OPRM1;OPRD1 GO:0007586| digestion CHRM3;UGT1A1 9031:[DB01183 DB13800] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0002576| platelet degranulation ALB;CALM1 GO:0055085| transmembrane transport SLCO1A2;CALM1;ABCB1 GO:0010033| response to organic substance CREB1;UGT1A1;CASQ1 GO:0007186| G-protein coupled receptor signaling pathway CALM1;OPRM1;OPRD1;OPRK1 9032:[DB01183 DB04527] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways GO:0002376| immune system process MASP2;TLR4 GO:0045087| innate immune response TLR4;MASP2 9033:[DB01183 DB08491] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08491|N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE MMP1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;MMP1 GO:0016032| viral reproduction MMP1;CREB1 9034:[DB01183 DB08613] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;HDAC4;TLR4;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC4;ESR1 GO:0071260| cellular response to mechanical stimulus HDAC4;TLR4 GO:0006351| transcription, DNA-dependent CREB1;HDAC4;ESR1 GO:0006954| inflammatory response HDAC4;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC4 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;HDAC4 GO:0042493| response to drug ABCB1;CREB1;HDAC4;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC4;CREB1;ESR1 GO:0006338| chromatin remodeling ESR1;HDAC4 GO:1903428| HDAC4;TLR4 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC4 GO:0008285| negative regulation of cell proliferation OPRM1;HDAC4 9035:[DB01183 DB01496] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007268| synaptic transmission GABRA5;OPRK1;OPRD1;OPRM1;GRIK2;CHRNA4;GRIA2 GO:0035094| response to nicotine CHRNA7;CHRNA4;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIK2;CHRNA4;GRIA2;CHRNA7 GO:0019233| sensory perception of pain OPRK1;CHRNA4;OPRM1;OPRD1 GO:0007626| locomotory behavior OPRK1;CHRNA4;OPRM1 GO:0006811| ion transport GABRA2;GABRA3;GABRA5;CHRNA4;GRIA2;CHRNA7;SLCO1A2;GABRA4;GABRA6;GRIK2;GABRA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CHRNA7;OPRM1 GO:0055085| transmembrane transport ABCB1;GRIK2;SLCO1A2 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0001666| response to hypoxia CHRNA7;CHRNA4;CREB1 GO:0007613| memory CHRNA7;CREB1 GO:0006810| transport ABCB1;GABRA5;GABRA3;GRIK2;GABRA6;GABRA4;GABRA1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1 GO:1900273| CREB1;CHRNA7 GO:0007165| signal transduction OPRK1;GABRA5;CREB1;TLR4;GRIA2;CHRNA4;CHRNA7;OPRM1;OPRD1;GABRA6;ESR1 9036:[DB01183 DB05194] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways GO:0071222| cellular response to lipopolysaccharide TLR4;CSF2;OPRK1 GO:0006955| immune response OPRD1;TLR4;CSF2;OPRK1 GO:0010628| positive regulation of gene expression CSF2;TLR4 GO:0044267| cellular protein metabolic process ALB;CSF2RA GO:0042116| macrophage activation CSF2;TLR4 9037:[DB01183 DB07384] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07384|1-ACETYL-2-CARBOXYPIPERIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 GO:0006811| ion transport SLCO1A2;ATP5B 9038:[DB01183 DB13994] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways GO:0006811| ion transport GABRA2;GABRA3;SLCO1A2 GO:0006810| transport ABCB1;GABRA3 9039:[DB01183 DB07712] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07712|3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes ESR1 common pathways GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;NCOA2 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 9040:[DB01183 DB07798] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07798|(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 9041:[DB01183 DB00414] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes ALB common pathways GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CBR1;UGT1A1;CYP2C9;CYP2C8 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SLCO1A2;KCNJ1 GO:0001895| retina homeostasis ALB GO:0030855| epithelial cell differentiation CES1;CBR1 GO:0044267| cellular protein metabolic process ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CBR1;CYP3A4 GO:0043687| post-translational protein modification ALB 9042:[DB01183 DB02670] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter SMARCA5;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;SMARCA5;CREB1 GO:0006338| chromatin remodeling ESR1;SMARCA5 GO:1990830| CREB1;SMARCA5 9043:[DB01183 DB02755] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02755|1-3 Sugar Ring of Pentamannosyl 6-Phosphate M6PR common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;M6PR GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;M6PR;ESR1 9044:[DB01183 DB00565] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00565|Cisatracurium CHRNA2 common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;CHRNA2;OPRD1;OPRM1;ESR1 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA2 GO:0035094| response to nicotine CHRNA2;CREB1 9045:[DB01183 DB06925] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways GO:0045087| innate immune response TLR4;LCK GO:0042493| response to drug ABCB1;LCK;UGT1A1;CREB1 GO:0016032| viral reproduction CREB1;LCK GO:0006468| protein phosphorylation LCK;CREB1 9046:[DB01183 DB08502] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08502|Capravirine CYP3A4 common genes CYP3A4 common pathways GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 9047:[DB01183 DB05685] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05685|FX06 CDH5 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;CDH5 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;CREB1 9048:[DB01183 DB00494] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;UGT1A9;CYP3A4;CES1 GO:0008152| metabolic process CES1;UGT1A9;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0032496| response to lipopolysaccharide UGT1A1;COMT;TLR4;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:1904224| UGT1A1;UGT1A9 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0042493| response to drug COMT;UGT1A1;CREB1;ABCB1 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A1;UGT1A9 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2C8;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0043627| response to estrogen stimulus ESR1;COMT;OPRK1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;COMT;OPRK1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0014070| response to organic cyclic compound UGT1A1;COMT 9049:[DB01183 DB01548] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes OPRK1;OPRM1;OPRD1 common pathways GO:1900745| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:1903715| OPRK1 GO:0045087| innate immune response TLR4;TRIM13 GO:0048148| behavioral response to cocaine OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4 GO:0009314| response to radiation OPRK1;OPRM1 GO:0007218| neuropeptide signaling pathway OPRK1;OPRM1;OPRD1 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TRIM13;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0033554| cellular response to stress OPRM1 GO:0042060| wound healing OPRM1 GO:0043278| response to morphine OPRK1;OPRM1 GO:0007600| sensory perception OPRM1;OPRK1 GO:1903937| OPRK1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0006955| immune response OPRD1;OPRK1;TLR4 GO:0042711| maternal behavior OPRK1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TRIM13;TLR4 GO:0040017| positive regulation of locomotion OPRK1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0032094| response to food OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:0051607| defense response to virus OPRK1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007610| behavior OPRK1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;TRIM13;ESR1;OPRM1;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:1990708| OPRK1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0044849| OPRK1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0038003| opioid receptor signaling pathway OPRM1;OPRD1;OPRK1 GO:0071456| cellular response to hypoxia OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0071315| cellular response to morphine OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1 GO:1901381| OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0008344| adult locomotory behavior OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0051881| regulation of mitochondrial membrane potential OPRD1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0042755| eating behavior OPRK1;OPRM1;OPRD1 9050:[DB01183 DB11256] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC46A1 9051:[DB01183 DB00315] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;HTR1B;CREB1;UGT1A1 GO:0007268| synaptic transmission HTR1F;OPRK1;HTR1B;OPRD1;HTR1D;OPRM1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0045471| response to ethanol OPRM1;UGT1A1;HTR1B;OPRK1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0042220| response to cocaine OPRM1;HTR1B;OPRK1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0009636| response to toxin CES1;HTR1D GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR1B;HTR1F;OPRD1;HTR1D;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;HTR1D;OPRM1;HTR1F;OPRK1;HTR1B GO:0007186| G-protein coupled receptor signaling pathway HTR1F;OPRK1;HTR1B;HTR1A;OPRD1;HTR1D;OPRM1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0007610| behavior HTR1A;OPRK1;HTR1B GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0007165| signal transduction TLR4;CREB1;HTR1B;HTR1F;OPRK1;OPRD1;HTR1D;OPRM1;HTR1A;ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 9052:[DB01183 DB11064] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11064|Homosalate PGR;AR;ESR1 common genes ESR1 common pathways GO:0006810| transport AR;ABCB1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;AR;TLR4;CREB1;PGR;OPRK1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0030879| mammary gland development PGR;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1;AR GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1;AR GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1;PGR GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1;PGR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;PGR;ESR1;AR GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0010629| negative regulation of gene expression PGR;CREB1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PGR;ESR1;AR GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;AR;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 9053:[DB01183 DB03152] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03152|B-2-Octylglucoside polA;aqpZ;TGM3;aqpZ;petB;petA;RHO common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;RHO;ESR1;OPRD1;OPRM1 GO:0006468| protein phosphorylation RHO;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;RHO 9054:[DB01183 DB05044] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05044|PSN357 PYGL common genes common pathways GO:0070266| necroptosis TLR4;PYGL GO:0008152| metabolic process UGT1A1;PYGL;CES1 9055:[DB01183 DB03926] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03926|5-Alpha-Androstane-3-Beta,17-Alpha-Diol SHBG common genes common pathways 9056:[DB01183 DB07720] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0035094| response to nicotine CHRNA7;CHRNA4;CHRNA2;CREB1;CHRNB4;CHRNB2 GO:0008542| visual learning CHRNB2;CREB1 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;CHRNA4 GO:0033603| positive regulation of dopamine secretion OPRK1;CHRNB2 GO:0007626| locomotory behavior OPRM1;CHRNA4;CHRNB4;CHRNB2;OPRK1;CHRNA3 GO:0019233| sensory perception of pain CHRNA4;OPRD1;OPRM1;OPRK1;CHRNB2 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;CHRNA4;CHRNA7;OPRM1;CHRNA3;CHRNB2;CHRNB4 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1;CHRNB2 GO:0030890| positive regulation of B cell proliferation TLR4;CHRNB2 GO:0001666| response to hypoxia CREB1;CHRNB2;CHRNA7;CHRNA4 GO:0042220| response to cocaine OPRM1;OPRK1;CHRNB2 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;TLR4 GO:0006811| ion transport CHRNA7;CHRNA2;CHRNA4;CHRFAM7A;SLCO1A2;CHRNA3;CHRNB4;CHRNB2 GO:0007165| signal transduction CHRFAM7A;ESR1;OPRD1;OPRM1;CHRNA7;CHRNA2;CHRNA4;TLR4;CHRNB4;CREB1;CHRNB2;OPRK1;CHRNA3 GO:1900273| CHRNA7;CREB1 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:0007613| memory CHRNA7;CHRNB2;CREB1 9057:[DB01183 DB07694] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process ALB;TTR 9058:[DB01183 DB05201] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05201|V24343 CNR1 common genes common pathways GO:0035094| response to nicotine CREB1;CNR1 GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;CNR1;UGT1A1;TLR4 GO:0045471| response to ethanol OPRM1;CNR1;UGT1A1;OPRK1 GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR1;OPRK1 GO:0043065| positive regulation of apoptotic process CNR1;CREB1 GO:0042220| response to cocaine OPRK1;OPRM1;CNR1 GO:0007584| response to nutrient CNR1;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CNR1;OPRD1;OPRM1;OPRK1 GO:0007613| memory CNR1;CREB1 GO:0007568| aging CREB1;CNR1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;CNR1;ESR1 9059:[DB01183 DB05451] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05451|P54 NFKB2;NFKB1 common genes common pathways GO:0007568| aging NFKB2;CREB1 GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB2;TLR4;NFKB1 GO:0007165| signal transduction NFKB2;TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;NFKB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;NFKB2;ESR1;NFKB1 GO:0048511| rhythmic process CREB1;NFKB2 GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;NFKB2;TLR4;OPRM1 GO:0006351| transcription, DNA-dependent NFKB1;ESR1;CREB1;NFKB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;NFKB2;TLR4;ESR1;NFKB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;NFKB1 GO:0043066| negative regulation of apoptotic process NFKB1;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB2;NFKB1;ESR1 GO:0045087| innate immune response TLR4;NFKB2;NFKB1 GO:0071260| cellular response to mechanical stimulus NFKB1;TLR4 GO:0010629| negative regulation of gene expression NFKB1;OPRD1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent NFKB2;CREB1;ESR1;NFKB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NFKB1;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;NFKB2;NFKB1 GO:0006954| inflammatory response NFKB2;TLR4;NFKB1 9060:[DB01183 DB03566] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;TXNRD1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0006811| ion transport SLC22A1;SLC22A4;SLCO1A2 GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0055085| transmembrane transport SLCO1A2;SLC22A4;ABCB1;SLC22A1 GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;OPRK1;ADRB1 GO:0098869| TXNRD1;ALB GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0007165| signal transduction TLR4;CREB1;ADRB1;OPRK1;OPRD1;OPRM1;ADRB2;ESR1;TXNRD1 GO:0015711| organic anion transport SLC22A1;SLC22A4;SLCO1A2 9061:[DB01183 DB09331] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09331|Daratumumab CD38 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;CD38 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CD38 GO:0097190| apoptotic signaling pathway CD38;TLR4 GO:0043066| negative regulation of apoptotic process ALB;CD38 GO:0001666| response to hypoxia CREB1;CD38 GO:0030890| positive regulation of B cell proliferation CD38;TLR4 GO:0032355| response to estradiol stimulus CD38;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;CD38 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;CD38 9062:[DB01183 DB01337] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01337|Pancuronium CHRNA2;CHRM2;CHRM3;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0035094| response to nicotine CHRNA2;CREB1 GO:0042493| response to drug ABCB1;UGT1A1;BCHE;CREB1 GO:0007586| digestion CHRM3;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA2 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0055085| transmembrane transport SLCO1A2;SLC22A2;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCB1 GO:0006811| ion transport CHRNA2;SLCO1A2;SLC22A2;SLC22A1 GO:0015711| organic anion transport SLC22A1;SLC22A2;SLCO1A2 GO:0007165| signal transduction CHRM3;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;CHRM2;CHRNA2 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;CHRM2;OPRM1;OPRD1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 9063:[DB01183 DB06111] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06111|AB192 MPO common genes common pathways GO:0007568| aging CREB1;MPO GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MPO;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0055114| oxidation-reduction process CYP3A4;MPO;CYP2C8 GO:0042742| defense response to bacterium MPO;TLR4 GO:0032094| response to food OPRM1;MPO 9064:[DB01183 DB00008] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00008|Peginterferon alfa-2a IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0051607| defense response to virus IFNAR2;OPRK1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;IFNAR1;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 9065:[DB01183 DB01977] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01977|6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;PLAU;OPRM1;OPRD1;ESR1 GO:0001666| response to hypoxia PLAU;CREB1 9066:[DB01183 DB04915] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04915|Idronoxil ENOX2 common genes common pathways GO:0048511| rhythmic process CREB1;ENOX2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;ENOX2 9067:[DB01183 DB04997] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04997|ATL1102 ITGA4 common genes common pathways 9068:[DB01183 DB05091] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05091|M0002 AVPR2 common genes common pathways GO:0032609| interferon-gamma production AVPR2;TLR4 GO:0010628| positive regulation of gene expression AVPR2;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;AVPR2;OPRM1;OPRD1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;AVPR2 GO:0032870| cellular response to hormone stimulus UGT1A1;AVPR2 GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;TLR4 9069:[DB01183 DB00018] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00018|Interferon alfa-n3 IFNAR1;IFNAR2 common genes common pathways GO:0051607| defense response to virus IFNAR2;OPRK1 GO:0032496| response to lipopolysaccharide IFNAR1;OPRM1;TLR4;UGT1A1 9070:[DB01183 DB07334] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07334|N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE KDR common genes common pathways GO:0016032| viral reproduction KDR;CREB1 GO:0010629| negative regulation of gene expression KDR;CREB1;ESR1;OPRD1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0043066| negative regulation of apoptotic process KDR;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;KDR;OPRM1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0030154| cell differentiation CREB1;KDR GO:0006468| protein phosphorylation CREB1;KDR 9071:[DB01183 DB08172] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;DHODH GO:0042594| response to starvation DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;DHODH GO:0007595| lactation CREB1;DHODH GO:0055114| oxidation-reduction process DHODH;CYP3A4;CYP2C8 GO:0042493| response to drug DHODH;UGT1A1;CREB1;ABCB1 9072:[DB01183 DB01962] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways GO:0006954| inflammatory response KIT;HCK;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;ESR1 GO:0016032| viral reproduction HCK;SRC;CREB1 GO:0008542| visual learning KIT;CREB1 GO:0048863| stem cell differentiation ESR1;KIT GO:0042493| response to drug UGT1A1;CREB1;ABCB1;SRC GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;SRC GO:0050727| regulation of inflammatory response HCK;ESR1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;SRC GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;SRC GO:0009314| response to radiation OPRK1;KIT;OPRM1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0071398| cellular response to fatty acid SRC;CREB1 GO:0060065| uterus development ESR1;SRC GO:0043066| negative regulation of apoptotic process ALB;HCK;SRC GO:0031663| lipopolysaccharide-mediated signaling pathway HCK;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;SRC GO:0045087| innate immune response TLR4;SRC;HCK GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;KIT GO:0008584| male gonad development ESR1;KIT GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0010628| positive regulation of gene expression SRC;KIT;TLR4 GO:0007411| axon guidance SRC;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;SRC;OPRM1 GO:0000187| activation of MAPK activity KIT;TLR4 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;SRC GO:0002376| immune system process HCK;SRC;TLR4 GO:0010863| positive regulation of phospholipase C activity KIT;ESR1 GO:0007165| signal transduction SRC;KIT;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0036120| SRC;CREB1 GO:0006468| protein phosphorylation CREB1;KIT;HCK;SRC GO:0030154| cell differentiation HCK;CREB1 GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0043069| negative regulation of programmed cell death KIT;ALB 9073:[DB01183 DB01835] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;NOS2;TLR4;UGT1A1 GO:0009617| response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;NOS2 9074:[DB01183 DB03419] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0016032| viral reproduction UCKL1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DPYD GO:0008152| metabolic process UCKL1;UGT1A1;CES1 9075:[DB01183 DB01296] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;NFKB2;TNF GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production TNF;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process IFNG;OPRM1;ESR1;TLR4;TNF GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0007165| signal transduction OPRK1;TLR4;NFKB2;CREB1;OPRD1;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;UGT1A1 GO:0097267| CYP2C8;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2C19;CYP2C8 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0032735| positive regulation of interleukin-12 production IFNG;TLR4 GO:0032700| negative regulation of interleukin-17 production TLR4;IFNG GO:0007568| aging CREB1;NFKB2 GO:0010628| positive regulation of gene expression TNF;TLR4;IFNG GO:0010033| response to organic substance UGT1A1;CREB1;TNF GO:0048511| rhythmic process CREB1;NFKB2 GO:0000187| activation of MAPK activity TLR4;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;TNF;OPRM1 GO:0006366| transcription from RNA polymerase II promoter NFKB2;CREB1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;MMP9 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TNF GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CES1;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2E1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;NFKB2;TNF;CREB1;ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TNF;TLR4 GO:0043065| positive regulation of apoptotic process TNF;MMP9;CREB1 GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0045672| positive regulation of osteoclast differentiation IFNG;CREB1;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB2;TNF;ESR1;IFNG GO:0045087| innate immune response TLR4;NFKB2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0032496| response to lipopolysaccharide TLR4;NFKB2;UGT1A1;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2E1;CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;NFKB2;ESR1 GO:0046330| positive regulation of JNK cascade TNF;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0000060| protein import into nucleus, translocation IFNG;OPRD1;TNF GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1;UGT1A1 GO:0097190| apoptotic signaling pathway TNF;TLR4 GO:0006955| immune response OPRD1;IFNG;TLR4;TNF;OPRK1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF GO:0006954| inflammatory response TNF;NFKB2;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;NFKB2;TNF GO:0045893| positive regulation of transcription, DNA-dependent CREB1;TNF;ESR1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0051607| defense response to virus IFNG;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NFKB2;CREB1 GO:0042493| response to drug CYP2E1;ABCB1;CREB1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19 GO:0010629| negative regulation of gene expression ESR1;OPRD1;IFNG;TNF;CREB1 GO:0042742| defense response to bacterium TNF;TLR4 GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2C19 9076:[DB01183 DB12866] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1 9077:[DB01183 DB02974] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2B6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2B6;CYP3A4 GO:0017144| drug metabolic process CYP2B6;UGT1A1;CYP2C8;CYP3A4 9078:[DB01183 DB00849] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;CHRNA4 GO:0006351| transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR1I2 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIK2;OPRM1;CHRNA7;CHRNA4;GRIA2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2B6 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;NR1I2;CYP2B6;CYP2C19;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;NR1I2;CREB1;ESR1 GO:0007626| locomotory behavior OPRM1;CHRNA4;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR1I2;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19;NR1I2;CYP2B6 GO:0007268| synaptic transmission GABRA5;OPRK1;OPRD1;OPRM1;GRIK2;CHRNA4;GRIA2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8;CYP2B6 GO:0035094| response to nicotine CHRNA4;CHRNA7;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2B6;NR1I2;CYP3A4 GO:0006810| transport ABCB1;GABRA3;GABRA5;GABRA1;GRIK2;GABRA6;GABRA4 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0007613| memory CHRNA7;CREB1 GO:1900273| CHRNA7;CREB1 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19;UGT1A1;CYP2B6 GO:0007165| signal transduction CHRNA7;CHRNA4;GRIA2;GABRA6;ESR1;OPRD1;OPRM1;OPRK1;NR1I2;TLR4;CREB1;GABRA5 GO:0006811| ion transport GABRA5;GABRA3;GABRA2;SLCO1A2;GABRA4;GABRA6;GRIK2;GABRA1;GRIA2;CHRNA4;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0055085| transmembrane transport ABCB1;SLCO1A2;GRIK2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;CHRNA7 GO:0001666| response to hypoxia CREB1;CHRNA4;CHRNA7 GO:0010628| positive regulation of gene expression NR1I2;TLR4 9079:[DB01183 DB04674] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0001666| response to hypoxia EDNRA;CREB1 GO:0015721| bile acid and bile salt transport ALB;AKR1C1;SLCO1A2 GO:0044267| cellular protein metabolic process ALB;TTR GO:0030855| epithelial cell differentiation CES1;AKR1C1 GO:0007165| signal transduction OPRK1;EDNRA;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;EDNRA GO:0006810| transport ABCB1;TTR GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;EDNRA;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;EDNRA GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;AKR1C1 GO:0006805| xenobiotic metabolic process CYP3A4;AKR1C1;CES1;CYP2C8 GO:0007586| digestion AKR1C1;UGT1A1 9080:[DB01183 DB13150] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways 9081:[DB01183 DB04827] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0008152| metabolic process PLA2G4A;UGT1A1;CES1 GO:0006629| lipid metabolic process PLA2G4A;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;MPO GO:0032094| response to food OPRM1;MPO GO:0042742| defense response to bacterium MPO;TLR4 GO:0055114| oxidation-reduction process CYP3A4;MPO;AOX1;CYP2C8 GO:0017144| drug metabolic process UGT1A1;AOX1;CYP2C8;CYP3A4 GO:0007568| aging CREB1;MPO 9082:[DB01183 DB00521] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction OPRK1;ADRB1;TLR4;CREB1;ADRB2;ESR1;OPRD1;OPRM1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRM1;OPRD1;OPRK1;ADRB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 9083:[DB01183 DB06842] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways GO:0071222| cellular response to lipopolysaccharide PDE4D;OPRK1;TLR4 GO:0032729| positive regulation of interferon-gamma production TLR4;PDE4D GO:0007165| signal transduction OPRK1;TLR4;CREB1;PDE4D;PDE4A;OPRD1;OPRM1;ESR1 GO:0007568| aging CREB1;PDE4D GO:0007186| G-protein coupled receptor signaling pathway OPRM1;PDE4A;OPRD1;PDE4D;OPRK1 9084:[DB01183 DB05419] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05419|ADX-10061 CALY common genes common pathways 9085:[DB01183 DB07695] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0044267| cellular protein metabolic process TTR;ALB 9086:[DB01183 DB07851] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9087:[DB01183 DB00852] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;FOS;UGT1A1;JUN GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0002376| immune system process IL2;TLR4 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0032757| positive regulation of interleukin-8 production TNF;TLR4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0007165| signal transduction OPRK1;ADRA2A;ADRB1;ADRA1A;TLR4;CREB1;ATF6;ADRB2;ESR1;OPRD1;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0050729| positive regulation of inflammatory response IL2;TLR4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;IL2;OPRK1;ADRA2A;ADRA1A;ADRB1 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A GO:0007568| aging ADRA1A;SLC6A3;CREB1;FOS;JUN GO:0006810| transport ABCB1;SLC6A2 GO:0007613| memory SLC6A4;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;IL2;OPRM1;ESR1 GO:1904646| TLR4;ADRB2 GO:0010628| positive regulation of gene expression ATF3;TLR4;TNF;ATF2;ATF4;SLC6A4 GO:0001666| response to hypoxia CREB1;SLC6A4 GO:0030890| positive regulation of B cell proliferation IL2;TLR4 GO:0048146| positive regulation of fibroblast proliferation JUN;ESR1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0010033| response to organic substance TNF;CREB1;UGT1A1;SLC6A4;JUN GO:0008285| negative regulation of cell proliferation OPRM1;JUN;ATF5;ADRA1A GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0048511| rhythmic process CREB1;ATF4 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0070373| negative regulation of ERK1 and ERK2 cascade ATF3;TLR4 GO:0009636| response to toxin SLC6A4;CES1;FOS GO:0014070| response to organic cyclic compound JUN;ATF1;FOS;UGT1A1;SLC6A3 GO:0000187| activation of MAPK activity TLR4;TNF GO:0042220| response to cocaine OPRM1;OPRK1;SLC6A3 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FOS;JUN GO:0006366| transcription from RNA polymerase II promoter ATF6;CREB1;FOS;ATF3;ATF2;ATF5;JUN;ESR1;ATF4;NFATC1;ATF1 GO:0055085| transmembrane transport SLC6A3;ABCB1;SLC6A2;SLC6A4;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade JUN;OPRM1;TLR4;TNF;ADRA1A GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0043066| negative regulation of apoptotic process ATF5;ALB;IL2;JUN GO:0043065| positive regulation of apoptotic process ATF4;JUN;TNF;CREB1;ATF6 GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0045672| positive regulation of osteoclast differentiation FOS;TNF;CREB1 GO:0007626| locomotory behavior OPRK1;SLC6A3;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFATC1;ATF1;JUN;ADRB2;ATF4;ESR1;ATF2;IL2;ATF5;TLR4;ATF3;TNF;FOS;ATF6;CREB1 GO:0009314| response to radiation OPRK1;OPRM1;JUN GO:0071222| cellular response to lipopolysaccharide OPRK1;TNF;TLR4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ATF3;TNF;JDP2;ATF2;ATF7 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0032729| positive regulation of interferon-gamma production TLR4;TNF;IL2 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0007623| circadian rhythm ATF5;CREB1;SLC6A4;JUN;ATF4 GO:0006357| regulation of transcription from RNA polymerase II promoter ATF1;ESR1;ATF4;ATF5;ATF2;ATF6;ATF3;FOS;JDP2 GO:0032496| response to lipopolysaccharide JUN;OPRM1;FOS;TLR4;UGT1A1 GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0006351| transcription, DNA-dependent ATF5;ATF2;ATF7;ATF3;CREB1;ATF6;JDP2;ATF1;NFATC1;ATF4;ESR1;JUN GO:0001889| liver development JUN;UGT1A1 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;ADRA1A;OPRK1 GO:0045471| response to ethanol SLC6A3;OPRK1;IL2;UGT1A1;OPRM1 GO:0097190| apoptotic signaling pathway TNF;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006955| immune response OPRD1;TLR4;TNF;OPRK1;IL2 GO:0016032| viral reproduction ATF7;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ATF2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0006954| inflammatory response TLR4;FOS;TNF GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007595| lactation SLC6A3;CREB1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0045893| positive regulation of transcription, DNA-dependent NFATC1;ESR1;ATF4;JUN;ATF5;CREB1;FOS;TNF GO:0007268| synaptic transmission SLC6A2;OPRK1;OPRD1;OPRM1 GO:0042493| response to drug ABCB1;ADRA1A;SLC6A3;SLC6A2;UGT1A1;FOS;CREB1;SLC6A4;JUN GO:0010629| negative regulation of gene expression TNF;CREB1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ATF5;ATF2;ATF7;FOS;ATF3;ATF6;CREB1;JDP2;NFATC1;ATF1;ATF4;ESR1;JUN GO:0042742| defense response to bacterium TNF;TLR4 GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2D6;CYP2C8 9088:[DB01183 DB03083] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03083|IC261 CSNK1G2 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;CSNK1G2;ESR1;TLR4;CREB1;OPRK1 GO:0006468| protein phosphorylation CSNK1G2;CREB1 9089:[DB01183 DB02773] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4;CES1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006954| inflammatory response PTGS1;TLR4 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;CYP2C8 GO:0098869| ALB;PTGS1 9090:[DB01183 DB06769] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06769|Bendamustine CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2 9091:[DB01183 DB05022] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;TOP2A;ESR1 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0007409| axonogenesis TOP2B;CREB1 GO:0048511| rhythmic process TOP2A;CREB1 9092:[DB01183 DB06972] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06972|7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile ITGAL common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;ITGAL;OPRM1;OPRD1 GO:0006954| inflammatory response TLR4;ITGAL 9093:[DB01183 DB00192] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00192|Indecainide SCN5A common genes common pathways GO:0006811| ion transport SLCO1A2;SCN5A GO:0055085| transmembrane transport SLCO1A2;SCN5A;ABCB1 9094:[DB01183 DB00534] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;ALDH5A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;ALDH5A1 GO:0006810| transport SLC12A1;ABCB1 GO:0006811| ion transport SLC12A1;SLCO1A2 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC12A1 9095:[DB01183 DB02215] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02215|Furoyl-Leucine ADAM28 common genes common pathways 9096:[DB01183 DB08299] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways GO:0007165| signal transduction PDE4A;OPRD1;PDE4D;OPRM1;ESR1;TLR4;CREB1;OPRK1;PDE4B GO:0007568| aging PDE4D;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;PDE4D;PDE4A;OPRD1;PDE4B;OPRK1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PDE4B;PDE4D GO:0032729| positive regulation of interferon-gamma production PDE4D;PDE4B;TLR4 9097:[DB01183 DB05210] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0010628| positive regulation of gene expression MTOR;TLR4 GO:0048146| positive regulation of fibroblast proliferation PRKDC;ESR1 GO:0014823| response to activity CREB1;PRKDC GO:0007584| response to nutrient UGT1A1;MTOR GO:0048511| rhythmic process PRKDC;CREB1 GO:0007411| axon guidance PIK3R1;CREB1 GO:0042220| response to cocaine MTOR;OPRK1;OPRM1 GO:0045671| negative regulation of osteoclast differentiation PIK3R1;TLR4 GO:0032868| response to insulin stimulus MTOR;OPRK1 GO:0050769| positive regulation of neurogenesis OPRM1;MTOR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;MTOR;TLR4 GO:0002376| immune system process TLR4;PRKDC GO:0007165| signal transduction MTOR;PIK3R2;TLR4;CREB1;OPRK1;PIK3R1;OPRD1;OPRM1;ESR1 GO:0009267| cellular response to starvation MTOR;ALB GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PIK3R1;OPRK1 GO:0050821| protein stabilization PIK3R1;CREB1 GO:0006468| protein phosphorylation PRKDC;PIK3R1;CREB1;MTOR GO:0071456| cellular response to hypoxia OPRD1;MTOR GO:0016032| viral reproduction PIK3R1;CREB1 GO:0043278| response to morphine OPRM1;MTOR;OPRK1 GO:0008542| visual learning MTOR;CREB1 GO:0042752| regulation of circadian rhythm PRKDC;CREB1 GO:0032760| positive regulation of tumor necrosis factor production PIK3R1;TLR4 GO:0008361| regulation of cell size CREB1;MTOR GO:0002218| activation of innate immune response PRKDC;TLR4 GO:0043066| negative regulation of apoptotic process ALB;PIK3R1;PRKDC GO:0043065| positive regulation of apoptotic process PRKDC;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PRKDC;ESR1;PIK3R1;PIK3R2;CREB1;TLR4 GO:0045087| innate immune response PRKDC;TLR4 GO:0046889| positive regulation of lipid biosynthetic process CREB1;MTOR GO:0042060| wound healing OPRM1;MTOR 9098:[DB01183 DB00963] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRM1;OPRK1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;UGT1A1;TLR4 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4;CES1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0042493| response to drug PTGS2;CREB1;UGT1A1;ABCB1 GO:0006954| inflammatory response TLR4;PTGS1;PTGS2 GO:0007613| memory PTGS2;CREB1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007568| aging CREB1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TLR4 GO:0098869| PTGS1;PTGS2;ALB GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 9099:[DB01183 DB07872] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07872|5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide F10 common genes common pathways 9100:[DB01183 DB00574] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00574|Fenfluramine SLC6A4;HTR2B;HTR2C;HTR2A;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0007610| behavior OPRK1;HTR2C;HTR2B;HTR2A GO:0007165| signal transduction CREB1;TLR4;HTR2C;HTR2B;OPRK1;ESR1;HTR2A;OPRM1;OPRD1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory HTR2A;SLC6A4;CREB1 GO:0007568| aging CREB1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR2B;HTR2C;OPRD1;OPRM1;HTR2A GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance SLC6A4;CREB1;UGT1A1 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2C;HTR2A GO:0001666| response to hypoxia CREB1;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC6A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;TLR4;HTR2B;HTR2C GO:0009636| response to toxin CES1;SLC6A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0007626| locomotory behavior OPRM1;OPRK1;HTR2C GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HTR2B GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2C;HTR2B;OPRD1;OPRM1;HTR2A;ESR1 GO:0019233| sensory perception of pain OPRK1;HTR2A;OPRD1;OPRM1 GO:0051000| positive regulation of nitric-oxide synthase activity HTR2B;ESR1 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0016032| viral reproduction CREB1;HTR2A GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0007268| synaptic transmission HTR2C;OPRK1;OPRM1;OPRD1;HTR2A GO:0042493| response to drug SLC6A4;HTR2A;HTR2C;HTR2B;ABCB1;CREB1;UGT1A1 9101:[DB01183 DB01819] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01819|Phosphoenolpyruvate aroG;kdsA;ENO3;PCK1;kdsA;SLCO2A1 common genes common pathways GO:0014823| response to activity PCK1;CREB1 GO:0055085| transmembrane transport SLCO2A1;ABCB1;SLCO1A2 GO:0032868| response to insulin stimulus OPRK1;PCK1 GO:0007568| aging PCK1;CREB1;ENO3 GO:0071456| cellular response to hypoxia OPRD1;PCK1 GO:0043252| sodium-independent organic anion transport SLCO2A1;ALB;SLCO1A2 GO:0042493| response to drug ENO3;CREB1;UGT1A1;ABCB1 GO:0006629| lipid metabolic process PCK1;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;PCK1;TLR4;UGT1A1 9102:[DB01183 DB05305] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05305|Cintredekin Besudotox IL13 common genes common pathways GO:0030890| positive regulation of B cell proliferation TLR4;IL13 GO:0043032| positive regulation of macrophage activation TLR4;IL13 GO:0006954| inflammatory response TLR4;IL13 GO:0006955| immune response OPRD1;IL13;OPRK1;TLR4 GO:0035094| response to nicotine IL13;CREB1 GO:1901215| CREB1;IL13 GO:0071260| cellular response to mechanical stimulus IL13;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;IL13 GO:0045471| response to ethanol UGT1A1;OPRK1;IL13;OPRM1 9103:[DB01183 DB06138] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06138|IRL-1620 EDNRB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;EDNRB GO:0071222| cellular response to lipopolysaccharide EDNRB;OPRK1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;EDNRB GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;EDNRB;OPRK1 GO:0019233| sensory perception of pain OPRD1;OPRM1;EDNRB;OPRK1 GO:0007194| negative regulation of adenylate cyclase activity EDNRB;OPRM1 GO:0032496| response to lipopolysaccharide EDNRB;UGT1A1;TLR4;OPRM1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;OPRK1;EDNRB GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;EDNRB GO:0007568| aging CREB1;EDNRB GO:0007186| G-protein coupled receptor signaling pathway EDNRB;OPRK1;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain EDNRB;OPRK1;OPRD1;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;EDNRB 9104:[DB01183 DB00289] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C19;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042493| response to drug SLC6A4;GRIN2A;ABCB1;SLC6A3;UGT1A1;SLC6A2;CREB1 GO:0007268| synaptic transmission SLC6A2;OPRK1;GRIN2B;OPRD1;OPRM1;GRIN2A GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0043278| response to morphine OPRM1;GRIN1;OPRK1 GO:0008542| visual learning CREB1;GRIN2A;GRIN1 GO:0051924| regulation of calcium ion transport OPRD1;GRIN3B GO:0007595| lactation CREB1;SLC6A3 GO:0019233| sensory perception of pain OPRK1;GRIN2A;OPRD1;GRIN1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2A;GRIN2B;OPRM1;GRIN1;GRIN2D;GRIN3B;GRIN3A;GRIN2C GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0045471| response to ethanol UGT1A1;GRIN3A;OPRK1;SLC6A3;GRIN1;OPRM1;GRIN2B;GRIN2A GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GRIN1;CREB1;TLR4 GO:0007626| locomotory behavior SLC6A3;OPRK1;OPRM1 GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;CREB1 GO:0042220| response to cocaine OPRM1;OPRK1;SLC6A3 GO:0008344| adult locomotory behavior GRIN2D;GRIN1;OPRD1 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLCO1A2;SLC6A4 GO:0036378| CYP3A4 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0009636| response to toxin CES1;SLC6A4 GO:0002933| CYP3A4;CYP2C8 GO:0006811| ion transport GRIN2A;GRIN2B;SLCO1A2;GRIN2D;GRIN1;GRIN3B;GRIN3A;GRIN2C GO:0051930| regulation of sensory perception of pain GRIN2D;OPRM1;OPRD1;GRIN2A;OPRK1 GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:1904646| GRIN1;GRIN2A;TLR4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:1903428| TLR4;GRIN1 GO:0006810| transport ABCB1;GRIN2C;SLC6A2;GRIN2A;GRIN2B GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging CREB1;SLC6A3 GO:0007613| memory GRIN2A;SLC6A4;GRIN1;CREB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;CYP2C19;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0097267| CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C19;CYP2C8;CYP2D6 GO:1900273| GRIN2A;CREB1 GO:0070588| calcium ion transmembrane transport GRIN3B;GRIN3A;OPRM1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 9105:[DB01183 DB07963] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport ABCB1;TTR 9106:[DB01183 DB11491] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 9107:[DB01183 DB02635] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways GO:1990830| BCAT2;CREB1 GO:0008152| metabolic process CES1;BCAT2;UGT1A1 9108:[DB01183 DB06751] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0006811| ion transport SLCO1A2;CACNA1C GO:0055085| transmembrane transport SLCO1A2;CACNA1C;ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;PDE4A GO:0007204| elevation of cytosolic calcium ion concentration CACNA1C;ESR1;OPRM1 GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1C GO:0007165| signal transduction ESR1;OPRD1;PDE4A;OPRM1;TLR4;CREB1;OPRK1 9109:[DB01183 DB04926] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04926|Neramexane GRIN3A common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIN3A GO:0045471| response to ethanol UGT1A1;GRIN3A;OPRK1;OPRM1 GO:0006811| ion transport GRIN3A;SLCO1A2 GO:0070588| calcium ion transmembrane transport GRIN3A;OPRM1 9110:[DB01183 DB07132] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways GO:0006351| transcription, DNA-dependent PDPK1;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PDPK1;ESR1 GO:0006468| protein phosphorylation CREB1;PDPK1 9111:[DB01183 DB01650] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCB1 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB 9112:[DB01183 DB03928] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03928|Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol CTH common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CTH GO:0043066| negative regulation of apoptotic process ALB;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CTH GO:1990830| CTH;CREB1 9113:[DB01183 DB01257] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01257|Eculizumab C5 common genes common pathways GO:0000187| activation of MAPK activity C5;TLR4 GO:0002376| immune system process TLR4;C5 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;C5 GO:0006954| inflammatory response TLR4;C5 GO:0045087| innate immune response TLR4;C5 9114:[DB01183 DB04392] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04392|Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] NQO1;azoR common genes common pathways GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0009636| response to toxin CES1;NQO1 GO:0007584| response to nutrient UGT1A1;NQO1 GO:0032355| response to estradiol stimulus NQO1;ESR1 GO:0007568| aging CREB1;NQO1 GO:0043086| negative regulation of catalytic activity UGT1A1;NQO1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NQO1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1;NQO1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;ALB 9115:[DB01183 DB03611] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03611|L-2-amino-4-methoxy-cis-but-3-enoic acid MAT1A common genes common pathways 9116:[DB01183 DB00150] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0002376| immune system process TLR4;IDO1 GO:0032735| positive regulation of interleukin-12 production IDO1;TLR4 GO:0051384| response to glucocorticoid stimulus UGT1A1;TPH2 GO:0071363| cellular response to growth factor stimulus OPRD1;DDC;CREB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC16A2 GO:0006810| transport SLC16A2;ABCB1 GO:0045600| positive regulation of fat cell differentiation TPH1;CREB1 GO:0010628| positive regulation of gene expression WARS;TLR4 GO:0043627| response to estrogen stimulus TPH2;OPRK1;ESR1 GO:0008285| negative regulation of cell proliferation WARS;OPRM1 GO:0014823| response to activity CREB1;TPH2 GO:0009636| response to toxin CES1;DDC GO:0055085| transmembrane transport SLCO1A2;SLC16A10;SLC16A2;ABCB1 GO:0043065| positive regulation of apoptotic process IDO1;CREB1 GO:0060749| mammary gland alveolus development ESR1;TPH1 GO:0007623| circadian rhythm DDC;CREB1;TPH2;TPH1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;IDO1;OPRM1 GO:0006954| inflammatory response TLR4;IDO1 GO:0055114| oxidation-reduction process TDO2;CYP3A4;TPH1;TPH2;CYP2C8;IDO1 9117:[DB01183 DB02825] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways 9118:[DB01183 DB02854] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HSD17B11;CYP2C8 GO:0042742| defense response to bacterium TLR4;IGHG2 GO:0006629| lipid metabolic process SULT2A1;CYP3A4;HSD17B11 GO:0007586| digestion UGT1A1;SULT2A1 GO:0045087| innate immune response TLR4;IGHG2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;SULT2A1 GO:0002376| immune system process TLR4;IGHG2 9119:[DB01183 DB06534] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06534|Thrombopoietin MPL common genes common pathways 9120:[DB01183 DB05166] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05166|APD668 GPR119 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GPR119;OPRD1;OPRM1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;GPR119;TLR4;CREB1 9121:[DB01183 DB01288] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0042755| eating behavior OPRD1;OPRM1;OPRK1;ADRB3 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:1904646| TLR4;ADRB2 GO:0007568| aging CREB1;ADRB3 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;OPRK1;ADRB3;ADRB1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ADRB3;ADRB1;ESR1;ADRB2;OPRM1;OPRD1 GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ADRB2 9122:[DB01183 DB04695] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04695|Farnesyl thiopyrophosphate ispU;GGPS1;MVK common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;MVK GO:0006629| lipid metabolic process CYP3A4;MVK GO:0006695| cholesterol biosynthetic process CES1;GGPS1;MVK 9123:[DB01183 DB12077] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12077|Urelumab TNFRSF9 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;TNFRSF9 GO:0006954| inflammatory response TNFRSF9;TLR4 GO:0006955| immune response TLR4;TNFRSF9;OPRK1;OPRD1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TNFRSF9;TLR4 GO:0097190| apoptotic signaling pathway TLR4;TNFRSF9 GO:0042981| regulation of apoptotic process ESR1;TNFRSF9;CREB1 9124:[DB01183 DB06274] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes OPRM1;OPRD1;OPRK1 common pathways GO:1901381| OPRK1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0071456| cellular response to hypoxia OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0044849| OPRM1;OPRK1 GO:1990708| OPRK1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0007610| behavior OPRK1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0051881| regulation of mitochondrial membrane potential OPRD1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4 GO:0008344| adult locomotory behavior OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0042220| response to cocaine OPRK1;OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0042060| wound healing OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0033554| cellular response to stress OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;OPRK1 GO:0009314| response to radiation OPRK1;OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0048148| behavioral response to cocaine OPRK1 GO:1903715| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:1900745| OPRK1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1 GO:0051607| defense response to virus OPRK1 GO:0032094| response to food OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:0042711| maternal behavior OPRK1 GO:0006955| immune response TLR4;OPRK1;OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0097237| OPRD1 GO:1903937| OPRK1 GO:0032100| positive regulation of appetite OPRM1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043278| response to morphine OPRM1;OPRK1 GO:0007600| sensory perception OPRM1;OPRK1 9125:[DB01183 DB11431] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes ABCB1;CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 GO:0006810| transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;UGT1A1;CYP2C8;CYP3A5 GO:0045332| phospholipid translocation ABCB1 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0055085| transmembrane transport SLCO1A2;ABCG2;ABCB1 GO:0036378| CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A7;CES1;CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP3A43;CYP2C8;CYP3A5 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;CREB1 9126:[DB01183 DB05042] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05042|SGS518 HTR6 common genes common pathways GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;HTR6 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;HTR6 GO:0007186| G-protein coupled receptor signaling pathway HTR6;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction CREB1;TLR4;HTR6;OPRK1;OPRM1;OPRD1;ESR1 9127:[DB01183 DB05688] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0007613| memory SLC6A4;CREB1 GO:0001666| response to hypoxia CREB1;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0010033| response to organic substance SLC6A4;CREB1;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0009636| response to toxin SLC6A4;CES1 GO:0055085| transmembrane transport ABCB1;SLC6A2;SLC6A4;SLCO1A2 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0042493| response to drug ABCB1;CREB1;SLC6A2;UGT1A1;SLC6A4 GO:0007268| synaptic transmission OPRD1;OPRM1;SLC6A2;OPRK1 9128:[DB01183 DB04958] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04958|Epratuzumab CD22 common genes common pathways 9129:[DB01183 DB04166] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways GO:0055114| oxidation-reduction process IL4I1;DAO;CYP2C8;CYP3A4 9130:[DB01183 DB00047] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways GO:0006468| protein phosphorylation CREB1;INSR;IGF1R GO:0007613| memory INSR;CREB1 GO:0007186| G-protein coupled receptor signaling pathway INSR;OPRK1;OPRM1;OPRD1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;INSR GO:0007165| signal transduction OPRD1;IGF1R;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;INSR GO:0000187| activation of MAPK activity TLR4;INSR GO:1904646| IGF1R;TLR4 GO:0008584| male gonad development INSR;ESR1 GO:0043066| negative regulation of apoptotic process ALB;IGF1R GO:0045893| positive regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0006355| regulation of transcription, DNA-dependent INSR;CREB1;ESR1 GO:0006955| immune response OPRK1;TLR4;OPRD1;IGF1R 9131:[DB01183 DB01483] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0001666| response to hypoxia CREB1;CHRNA7;CHRNA4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0006811| ion transport GABRA3;GABRA5;GABRA2;SLCO1A2;GABRA1;GABRA4;GABRA6;GRIK2;GRIA2;CHRNA4;CHRNA7 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0055085| transmembrane transport GRIK2;SLCO1A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CHRNA7;OPRM1 GO:0000187| activation of MAPK activity TLR4;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:1900273| CREB1;CHRNA7 GO:0007165| signal transduction OPRM1;OPRD1;GABRA6;ESR1;CHRNA4;GRIA2;CHRNA7;GABRA5;CREB1;TLR4;OPRK1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;UGT1A1;CYP3A4 GO:0097267| CYP2C8;CYP2C19 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4 GO:0007613| memory CREB1;CHRNA7 GO:0006810| transport GABRA4;GABRA6;GRIK2;GABRA1;ABCB1;GABRA5;GABRA3 GO:0035094| response to nicotine CREB1;CHRNA4;CHRNA7 GO:0007268| synaptic transmission OPRK1;GABRA5;CHRNA4;GRIA2;OPRD1;OPRM1;GRIK2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19 GO:0007626| locomotory behavior OPRK1;OPRM1;CHRNA4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIK2;GRIA2;CHRNA4;CHRNA7 GO:0042737| drug catabolic process CYP3A4 GO:0019233| sensory perception of pain OPRD1;OPRM1;CHRNA4;OPRK1 9132:[DB01183 DB12890] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12890|Dihydrexidine DRD1 common genes common pathways GO:0042220| response to cocaine DRD1;OPRM1;OPRK1 GO:0010628| positive regulation of gene expression DRD1;TLR4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRD1;OPRM1 GO:0014002| astrocyte development TLR4;DRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;DRD1;OPRK1 GO:0007613| memory DRD1;CREB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;DRD1 GO:0042493| response to drug DRD1;ABCB1;UGT1A1;CREB1 GO:0042711| maternal behavior OPRK1;DRD1 GO:0008542| visual learning DRD1;CREB1 GO:0048148| behavioral response to cocaine DRD1;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;OPRM1 GO:0007626| locomotory behavior OPRK1;OPRM1;DRD1 9133:[DB01183 DB00130] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLC16A10;SLC38A3;ABCB1 GO:0032868| response to insulin stimulus OPRK1;CAD GO:0009636| response to toxin SLC7A8;ASNS;CES1 GO:0006811| ion transport SLC38A3;SLCO1A2 GO:1990830| GFPT2;CREB1 GO:0006810| transport SLC7A8;ABCB1 GO:0009267| cellular response to starvation ALB;GLUL GO:0050729| positive regulation of inflammatory response TLR4;TGM2 GO:0017144| drug metabolic process CYP3A4;CAD;CYP2C8;UGT1A1 GO:0032870| cellular response to hormone stimulus ASNS;UGT1A1 GO:0002376| immune system process CTPS1;TLR4 GO:0031100| organ regeneration CAD;UGT1A1;PPAT GO:0007268| synaptic transmission OPRD1;OPRM1;GLS;OPRK1 GO:0042493| response to drug UGT1A1;CTPS1;CREB1;PFAS;ABCB1;PPAT GO:0007595| lactation PPAT;CAD;CREB1 GO:0016032| viral reproduction CREB1;SLC1A5 GO:0001889| liver development UGT1A1;CAD;ASNS GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TGM2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;TGM2;OPRM1;OPRK1 GO:0042594| response to starvation CAD;UGT1A1 GO:0042981| regulation of apoptotic process ESR1;CREB1;GLS2 GO:0043066| negative regulation of apoptotic process ALB;ASNS GO:0008152| metabolic process CAD;UGT1A1;PPAT;CES1 GO:0002576| platelet degranulation ALB;F13A1 GO:0043065| positive regulation of apoptotic process TGM2;CREB1 9134:[DB01183 DB06579] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0006811| ion transport GABRG3;GABRA1;GABRA6;GABRA4;GABRG2;SLCO1A2;GABRA2;GABRA3;GABRA5;GABRG1 GO:0006810| transport ABCB1;GABRA3;GABRA5;GABRA1;GABRA4;GABRA6;GABRG2 GO:0007165| signal transduction OPRD1;OPRM1;GABRA6;ESR1;OPRK1;GABRA5;TLR4;CREB1 GO:0042493| response to drug GABRG3;ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission OPRM1;OPRD1;GABRG2;GABRG1;GABRA5;OPRK1 9135:[DB01183 DB00459] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00459|Acitretin RXRA;RARA;RARB;RARG;RXRB;RXRG;RBP1;CYP26A1;ALB common genes ALB common pathways GO:0016032| viral reproduction RXRA;CREB1 GO:0071391| cellular response to estrogen stimulus RARA;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARA;RARG;ESR1;RARB;RXRG;RXRB;RXRA GO:0008361| regulation of cell size CREB1;RARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CREB1;RARA;ESR1 GO:0010629| negative regulation of gene expression CREB1;RARA;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;RXRB;RXRA;RXRG;RARB;ESR1;RARG;RARA GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP26A1 GO:0043687| post-translational protein modification ALB GO:0006805| xenobiotic metabolic process CYP2C8;CYP26A1;CES1;CYP3A4 GO:0043066| negative regulation of apoptotic process RARB;ALB;RARA;RARG GO:0002576| platelet degranulation ALB GO:0043065| positive regulation of apoptotic process RARB;CREB1;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;RXRA;RXRB;CREB1;RXRG;RARB;ESR1;RARG;RARA GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;RARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;RARB;ESR1;RARA;RARG GO:0042981| regulation of apoptotic process CREB1;RARA;ESR1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA GO:0043401| steroid hormone mediated signaling pathway RARB;RXRG;RXRB;RXRA;RARA;RARG;ESR1 GO:0006351| transcription, DNA-dependent RARA;RARG;ESR1;RARB;RXRG;RXRB;RXRA;CREB1 GO:0001889| liver development RARA;UGT1A1 GO:0045471| response to ethanol OPRK1;UGT1A1;RARA;OPRM1 GO:0010628| positive regulation of gene expression RARG;RARA;TLR4 GO:0008584| male gonad development ESR1;RARA GO:0015721| bile acid and bile salt transport RXRA;ALB;SLCO1A2 GO:1990830| RARG;CREB1 GO:0008285| negative regulation of cell proliferation RARA;RARG;OPRM1;RARB GO:0042573| retinoic acid metabolic process UGT1A1;CYP26A1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0032689| negative regulation of interferon-gamma production RARA;TLR4 GO:0032720| negative regulation of tumor necrosis factor production RARA;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;RARA;TLR4;CREB1;RARB;OPRK1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0032355| response to estradiol stimulus RARA;ESR1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006468| protein phosphorylation CREB1;RARA 9136:[DB01183 DB07427] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;HBB;TLR4 GO:0098869| HBB;HBA1;ALB GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 9137:[DB01183 DB00117] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways GO:0006811| ion transport SLC38A3;SLCO1A2 GO:0055085| transmembrane transport ABCB1;SLC16A10;SLCO1A2;SLC38A3 9138:[DB01183 DB03976] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03976|Phosphorylisopropane PRSS1;PRSS2;CTRB1;BCHE common genes common pathways GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0042493| response to drug CREB1;UGT1A1;BCHE;ABCB1 GO:0007586| digestion PRSS1;PRSS2;UGT1A1;CTRB1 9139:[DB01183 DB04472] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways GO:0032720| negative regulation of tumor necrosis factor production TLR4;LGALS9 GO:0032689| negative regulation of interferon-gamma production LGALS9;TLR4 GO:0002376| immune system process LGALS9;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade LGALS9;OPRM1;TLR4 GO:0034142| toll-like receptor 4 signaling pathway TLR4;LGALS9 GO:0010628| positive regulation of gene expression TLR4;LGALS9 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;LGALS9 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;LGALS9 GO:0042346| positive regulation of NF-kappaB import into nucleus LGALS9;TLR4 GO:0010629| negative regulation of gene expression OPRD1;LGALS9;ESR1;CREB1 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;LGALS9 GO:0006954| inflammatory response TLR4;LGALS9 GO:0051092| positive regulation of NF-kappaB transcription factor activity LGALS9;TLR4 9140:[DB01183 DB06749] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways GO:0006811| ion transport SLCO1A2;SLCO1B3 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLCO1B3 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B3;ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1A2;ALB GO:0015711| organic anion transport SLCO1A2;SLCO1B3 9141:[DB01183 DB00978] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;TOP2A;CREB1 GO:0071222| cellular response to lipopolysaccharide ABCC2;OPRK1;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1;ABCC2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0042493| response to drug CYP1A2;ABCB1;ABCC2;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0015711| organic anion transport SLC22A5;SLCO1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0006810| transport ABCC2;ABCB1 GO:0043627| response to estrogen stimulus ABCC2;OPRK1;ESR1 GO:0048511| rhythmic process CREB1;TOP2A GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0006811| ion transport SLC22A5;SLCO1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0006855| drug transmembrane transport ABCC2;ABCB1;SLC22A5 GO:0055085| transmembrane transport SLCO1A2;SLC22A5;ABCB1;ABCC2 9142:[DB01183 DB06714] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;TAAR1;OPRK1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;TAAR1;ESR1;OPRM1;OPRD1 GO:0009636| response to toxin SLC18A2;CES1 GO:0055085| transmembrane transport SLCO1A2;SLC18A2;ABCB1 GO:0007626| locomotory behavior OPRM1;SLC18A2;OPRK1 GO:0007268| synaptic transmission OPRM1;OPRD1;SLC18A2;OPRK1 9143:[DB01183 DB08210] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08210|2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE GCK common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;GCK 9144:[DB01183 DB01463] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01463|Fencamfamine SLC6A3 common genes common pathways GO:0045471| response to ethanol SLC6A3;OPRK1;UGT1A1;OPRM1 GO:0007626| locomotory behavior OPRM1;OPRK1;SLC6A3 GO:0042493| response to drug SLC6A3;ABCB1;CREB1;UGT1A1 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007595| lactation CREB1;SLC6A3 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging SLC6A3;CREB1 GO:0042220| response to cocaine OPRM1;OPRK1;SLC6A3 GO:0055085| transmembrane transport SLCO1A2;SLC6A3;ABCB1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 9145:[DB01183 DB04929] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04929|DG031 ALOX5AP common genes common pathways 9146:[DB01183 DB04602] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 9147:[DB01183 DB01561] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01561|Androstanedione HSD17B1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HSD17B1 GO:0008210| estrogen metabolic process UGT1A1;HSD17B1 GO:0055114| oxidation-reduction process HSD17B1;CYP3A4;CYP2C8 9148:[DB01183 DB08597] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08597|6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine ACVR1;FKBP1A common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ACVR1;ESR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ACVR1 GO:0007179| transforming growth factor beta receptor signaling pathway ACVR1;FKBP1A;CREB1 GO:0006468| protein phosphorylation CREB1;ACVR1 GO:0070588| calcium ion transmembrane transport FKBP1A;OPRM1 9149:[DB01183 DB07605] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07605|2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE F10 common genes common pathways 9150:[DB01183 DB08733] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08733|(2R,3R)-N^1^-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N^4^-HYDROXY-2-(2-METHYLPROPYL)-3-{[(1,3-THIAZOL-2-YLCARBONYL)AMINO]METHYL}BUTANEDIAMIDE ADAM28 common genes common pathways 9151:[DB01183 DB03917] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways GO:0060068| vagina development RBP4;ESR1 GO:0045471| response to ethanol OPRM1;RBP4;UGT1A1;OPRK1 GO:0060065| uterus development RBP4;ESR1 9152:[DB01183 DB05290] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05290|SPP 301 EDNRA common genes common pathways GO:0001666| response to hypoxia EDNRA;CREB1 GO:0007165| signal transduction OPRK1;EDNRA;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;EDNRA;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;EDNRA;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;EDNRA 9153:[DB01183 DB09142] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09142|Sincalide SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLCO1B3 GO:0006811| ion transport SLCO1A2;SLCO1B3 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B3;ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B3;ALB GO:0015711| organic anion transport SLCO1A2;SLCO1B3 9154:[DB01183 DB06342] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 9155:[DB01183 DB04299] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0051384| response to glucocorticoid stimulus GOT1;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;ESR1 GO:0016032| viral reproduction TPR;CREB1 9156:[DB01183 DB03807] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;PDE4B;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PDE4B GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PDE4B GO:0032729| positive regulation of interferon-gamma production TLR4;PDE4B 9157:[DB01183 DB07194] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways GO:0045087| innate immune response SYK;TLR4 GO:0006954| inflammatory response SYK;TLR4 GO:0016032| viral reproduction CREB1;SYK GO:0042742| defense response to bacterium SYK;TLR4 GO:0002376| immune system process TLR4;SYK GO:0006468| protein phosphorylation CREB1;SYK GO:0000187| activation of MAPK activity TLR4;SYK 9158:[DB01183 DB09108] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09108|Simoctocog Alfa VWF common genes common pathways GO:0002576| platelet degranulation ALB;VWF 9159:[DB01183 DB07423] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;AR;ESR1 GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0016579| protein deubiquitination ESR1;AR GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0007165| signal transduction OPRK1;TLR4;CREB1;AR;OPRD1;OPRM1;ESR1 GO:0006810| transport AR;ABCB1 9160:[DB01183 DB02323] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02323|EM-1745 HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;HSD17B1;CYP3A4 GO:0008210| estrogen metabolic process UGT1A1;HSD17B1 GO:0006629| lipid metabolic process CYP3A4;HSD17B1 9161:[DB01183 DB00305] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00305|Mitomycin POR common genes common pathways GO:0007584| response to nutrient POR;UGT1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;POR;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;POR GO:0042493| response to drug POR;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;POR 9162:[DB01183 DB02542] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways GO:0008584| male gonad development UBB;ESR1 GO:0016579| protein deubiquitination UBB;ESR1 GO:0044267| cellular protein metabolic process UBB;ALB GO:0007179| transforming growth factor beta receptor signaling pathway UBB;CREB1 GO:0000187| activation of MAPK activity TLR4;UBB GO:0051881| regulation of mitochondrial membrane potential OPRD1;UBB GO:0055085| transmembrane transport UBB;SLCO1A2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle UBB;ABCB1 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;UBB GO:0035666| TRIF-dependent toll-like receptor signaling pathway TLR4;UBB GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;UBB GO:0002755| MyD88-dependent toll-like receptor signaling pathway UBB;TLR4 GO:0043066| negative regulation of apoptotic process ALB;UBB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;UBB;ESR1 GO:0043065| positive regulation of apoptotic process UBB;CREB1 GO:0045087| innate immune response TLR4;UBB GO:0000122| negative regulation of transcription from RNA polymerase II promoter UBB;ESR1 GO:0002756| MyD88-independent toll-like receptor signaling pathway TLR4;UBB GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;UBB 9163:[DB01183 DB01047] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;NR3C1;OPRM1;SMO;ESR1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0040018| positive regulation of multicellular organism growth CREB1;SMO GO:0050821| protein stabilization CREB1;SMO GO:0007186| G-protein coupled receptor signaling pathway OPRK1;SMO;OPRD1;OPRM1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression TLR4;SMO GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0002933| CYP2C8;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter SMO;ESR1;NR3C1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;SMO;NR3C1;CREB1;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0043066| negative regulation of apoptotic process SMO;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0006351| transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0010629| negative regulation of gene expression SMO;ESR1;OPRD1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent SMO;ESR1;CREB1 9164:[DB01183 DB04464] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0016032| viral reproduction HLA-B;CREB1 GO:0006955| immune response HLA-B;OPRD1;OPRK1;B2M;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;UBC GO:0007595| lactation MT-CO2;CREB1;SERPINC1 GO:0042493| response to drug CREB1;B2M;UGT1A1;MT-ND1;ABCB1 GO:0051607| defense response to virus OPRK1;RNASE1 GO:0055114| oxidation-reduction process CYP2C8;MT-CO1;MT-ND1;MT-CO2;CYP3A4 GO:0043687| post-translational protein modification RABGGTA;ALB;SERPINC1;RABGGTB GO:0002755| MyD88-dependent toll-like receptor signaling pathway UBC;TLR4 GO:0043066| negative regulation of apoptotic process UBC;ALB GO:0043065| positive regulation of apoptotic process S100B;UBC;CREB1 GO:0050829| defense response to Gram-negative bacterium TLR4;B2M GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;B2M GO:0045944| positive regulation of transcription from RNA polymerase II promoter UBC;CREB1;TLR4;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;UBC GO:0045087| innate immune response UBC;TLR4;B2M;S100B;HLA-B GO:0042981| regulation of apoptotic process CREB1;RABGGTA;ESR1;RABGGTB GO:0002756| MyD88-independent toll-like receptor signaling pathway TLR4;UBC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade UBC;TLR4;S100B GO:0016579| protein deubiquitination UBC;ESR1 GO:0007584| response to nutrient SERPINC1;COX4I1;UGT1A1 GO:0014070| response to organic cyclic compound MT-ND1;UGT1A1 GO:0007409| axonogenesis CREB1;S100B GO:0001895| retina homeostasis B2M;ALB GO:0000187| activation of MAPK activity TLR4;UBC GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;UBC GO:0044267| cellular protein metabolic process SERPINC1;ALB;UBC;B2M GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;UBC GO:0055085| transmembrane transport SLCO1A2;UBC;ABCB1 GO:0007249| I-kappaB kinase/NF-kappaB cascade UBC;TLR4 GO:0002376| immune system process B2M;TLR4;HLA-B GO:0051384| response to glucocorticoid stimulus UGT1A1;S100B GO:0035666| TRIF-dependent toll-like receptor signaling pathway TLR4;UBC GO:0007568| aging MT-CO1;CREB1 GO:0007613| memory S100B;CREB1 GO:0071456| cellular response to hypoxia S100B;OPRD1 9165:[DB01183 DB02796] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02796|9-Deazainosine PNP common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PNP GO:0006955| immune response OPRD1;PNP;TLR4;OPRK1 9166:[DB01183 DB02162] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;HINT1;CREB1 GO:0006355| regulation of transcription, DNA-dependent HINT1;ESR1;CREB1 GO:0007165| signal transduction HINT1;ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1 9167:[DB01183 DB08374] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways GO:0007586| digestion CTRB1;UGT1A1 9168:[DB01183 DB04260] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;PNP;CREB1 GO:0006955| immune response PNP;TLR4;OPRK1;OPRD1 9169:[DB01183 DB08357] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways 9170:[DB01183 DB00010] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00010|Sermorelin GHRHR common genes common pathways GO:0007595| lactation CREB1;GHRHR GO:0046887| positive regulation of hormone secretion GHRHR;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;GHRHR GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;GHRHR GO:0040018| positive regulation of multicellular organism growth CREB1;GHRHR GO:0007165| signal transduction OPRK1;TLR4;GHRHR;CREB1;OPRD1;OPRM1;ESR1 GO:0030879| mammary gland development CREB1;GHRHR GO:0032868| response to insulin stimulus OPRK1;GHRHR GO:0043627| response to estrogen stimulus ESR1;OPRK1;GHRHR 9171:[DB01183 DB08362] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08362|N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ESR1;CREB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;CSNK2A1;OPRD1;OPRM1;ESR1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0048511| rhythmic process CSNK2A1;CREB1 9172:[DB01183 DB03523] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03523|Brequinar DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation UGT1A1;DHODH GO:0007595| lactation DHODH;CREB1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;DHODH GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHODH 9173:[DB01183 DB05941] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05941|Leronlimab CCR5 common genes common pathways GO:0006954| inflammatory response TLR4;CCR5 GO:0016032| viral reproduction CREB1;CCR5 GO:0006955| immune response OPRD1;CCR5;TLR4;OPRK1 GO:0071222| cellular response to lipopolysaccharide CCR5;TLR4;OPRK1 GO:0007165| signal transduction OPRK1;CREB1;CCR5;TLR4;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CCR5;OPRK1;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;CCR5 9174:[DB01183 DB13929] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13929|Relcovaptan OXTR;AVPR1A common genes common pathways GO:0042711| maternal behavior OPRK1;AVPR1A;OXTR GO:0007595| lactation CREB1;OXTR GO:0042493| response to drug OXTR;ABCB1;UGT1A1;CREB1 GO:0032870| cellular response to hormone stimulus OXTR;AVPR1A;UGT1A1 GO:0044849| OXTR;OPRM1;OPRK1 GO:0048545| response to steroid hormone stimulus OXTR;UGT1A1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;AVPR1A;ESR1;OXTR;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus ESR1;OXTR GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;OXTR;AVPR1A GO:0007613| memory CREB1;OXTR GO:0007204| elevation of cytosolic calcium ion concentration ESR1;AVPR1A;OXTR;OPRM1 GO:0010033| response to organic substance AVPR1A;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound OXTR;UGT1A1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1;OXTR GO:0042220| response to cocaine OPRM1;OXTR;OPRK1 9175:[DB01183 DB03589] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03589|Alpha-Ketomalonic Acid ME2 common genes common pathways GO:0055114| oxidation-reduction process ME2;CYP3A4;CYP2C8 GO:0008152| metabolic process UGT1A1;CES1;ME2 9176:[DB01183 DB00036] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways GO:0043066| negative regulation of apoptotic process HPN;ALB GO:0071222| cellular response to lipopolysaccharide TFPI;OPRK1;TLR4 GO:0007623| circadian rhythm CREB1;F7 GO:0032496| response to lipopolysaccharide TFPI;UGT1A1;TLR4;OPRM1 GO:0031100| organ regeneration F7;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;F7;TFPI GO:0043627| response to estrogen stimulus OPRK1;F7;ESR1 GO:0001666| response to hypoxia CREB1;F7 GO:0010628| positive regulation of gene expression TLR4;HPN GO:0014070| response to organic cyclic compound UGT1A1;F7 9177:[DB01183 DB07567] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes ESR1 common pathways GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 9178:[DB01183 DB03660] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 9179:[DB01183 DB06916] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways GO:0001666| response to hypoxia NOS2;CREB1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;NOS2;OPRM1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0010629| negative regulation of gene expression CREB1;NOS2;ESR1;OPRD1 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0009617| response to bacterium TLR4;NOS2 9180:[DB01183 DB12271] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways GO:0050821| protein stabilization CREB1;CPN2 GO:0051384| response to glucocorticoid stimulus UGT1A1;CPN1 9181:[DB01183 DB03060] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03060|Sri-9662 DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process DHFR;CYP2C8;CYP3A4 9182:[DB01183 DB01307] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01307|Insulin Detemir INSR;ALB common genes ALB common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;INSR GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0000187| activation of MAPK activity INSR;TLR4 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0008584| male gonad development INSR;ESR1 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway INSR;OPRK1;OPRD1;OPRM1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;INSR GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0006468| protein phosphorylation CREB1;INSR GO:0007613| memory CREB1;INSR GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;INSR 9183:[DB01183 DB01571] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes OPRK1;OPRM1;OPRD1 common pathways GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0008344| adult locomotory behavior OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0051881| regulation of mitochondrial membrane potential OPRD1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0044849| OPRM1;OPRK1 GO:1990708| OPRK1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007610| behavior OPRK1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1 GO:1901381| OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071456| cellular response to hypoxia OPRD1 GO:0006955| immune response OPRK1;TLR4;OPRD1 GO:0042711| maternal behavior OPRK1 GO:0043278| response to morphine OPRK1;OPRM1 GO:0007600| sensory perception OPRK1;OPRM1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0097237| OPRD1 GO:1903937| OPRK1 GO:0032100| positive regulation of appetite OPRM1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0032094| response to food OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1 GO:0051607| defense response to virus OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0048148| behavioral response to cocaine OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4 GO:0007626| locomotory behavior OPRK1;OPRM1 GO:0009314| response to radiation OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;OPRK1 GO:1900745| OPRK1 GO:1903715| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:0042060| wound healing OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0033554| cellular response to stress OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 9184:[DB01183 DB01408] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;ADRB2;OPRM1;OPRD1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB2;OPRM1;OPRD1 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:1904646| TLR4;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ADRB2 GO:0042493| response to drug ABCB1;UGT1A1;BCHE;CREB1 9185:[DB01183 DB02689] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02689|S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine ARG1 common genes common pathways GO:0002376| immune system process ARG1;TLR4 GO:0048545| response to steroid hormone stimulus UGT1A1;ARG1 GO:0007568| aging ARG1;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;ARG1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ARG1 GO:0045087| innate immune response TLR4;ARG1 GO:0032496| response to lipopolysaccharide ARG1;OPRM1;TLR4;UGT1A1 GO:0001889| liver development ARG1;UGT1A1 GO:0042493| response to drug ARG1;ABCB1;UGT1A1;CREB1 9186:[DB01183 DB00340] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRM1;OPRD1 GO:0007165| signal transduction OPRM1;CHRM5;OPRD1;ESR1;CHRM1;CHRM2;CHRM4;OPRK1;CHRM3;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;CHRM4;OPRK1;OPRD1;CHRM5;OPRM1;CHRM2;CHRM1 GO:0007586| digestion UGT1A1;CHRM3 9187:[DB01183 DB08737] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes ESR1 common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 9188:[DB01183 DB04343] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A3;SLCO1A2 9189:[DB01183 DB04478] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ABCB1;SORD GO:0055114| oxidation-reduction process SORD;CYP3A4;CYP2C8 9190:[DB01183 DB00324] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NR3C1;ESR1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;NR3C1;OPRM1;ESR1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 9191:[DB01183 DB07380] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways GO:0007586| digestion UGT1A1;CTRB1 9192:[DB01183 DB02067] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways GO:1990830| CREB1;SHMT1 9193:[DB01183 DB03341] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways GO:0014070| response to organic cyclic compound AANAT;UGT1A1 GO:0032868| response to insulin stimulus OPRK1;AANAT GO:0048511| rhythmic process CREB1;AANAT GO:0007623| circadian rhythm CREB1;AANAT 9194:[DB01183 DB02477] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02477|[Cyclohexylethyl]-[[[[4-[2-Methyl-1-Imidazolyl-Butyl]Phenyl]Acetyl]-Seryl]-Lysinyl]-Amine NMT1 common genes common pathways 9195:[DB01183 DB05072] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05072|AV608 TACR1 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;TACR1;OPRM1;OPRD1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration TACR1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;TACR1;OPRK1 GO:0032355| response to estradiol stimulus TACR1;ESR1 GO:0014070| response to organic cyclic compound TACR1;UGT1A1 GO:0042755| eating behavior OPRD1;OPRM1;TACR1;OPRK1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;TACR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;TACR1;OPRK1 GO:0045471| response to ethanol TACR1;OPRM1;UGT1A1;OPRK1 GO:0050671| positive regulation of lymphocyte proliferation TLR4;TACR1 GO:0035094| response to nicotine CREB1;TACR1 GO:0043278| response to morphine OPRK1;OPRM1;TACR1 GO:0046887| positive regulation of hormone secretion CREB1;TACR1 GO:0006954| inflammatory response TACR1;TLR4 GO:0007268| synaptic transmission TACR1;OPRM1;OPRD1;OPRK1 9196:[DB01183 DB02648] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways GO:0051791| medium-chain fatty acid metabolic process CROT;CES1 GO:0006629| lipid metabolic process CRAT;CYP3A4;CROT 9197:[DB01183 DB06406] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06406|Idraparinux F10 common genes common pathways 9198:[DB01183 DB02583] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity DHFR;ESR1 GO:0055114| oxidation-reduction process DHFR;CYP2C8;CYP3A4 9199:[DB01183 DB04230] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 9200:[DB01183 DB02078] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways GO:0007411| axon guidance CREB1;FYN GO:0033138| positive regulation of peptidyl-serine phosphorylation PFN2;OPRD1 GO:0002376| immune system process FYN;TLR4 GO:0030154| cell differentiation FYN;CREB1 GO:0006468| protein phosphorylation FYN;CREB1 GO:0036120| FYN;CREB1 GO:0050821| protein stabilization CREB1;PFN2 GO:0071363| cellular response to growth factor stimulus OPRD1;FYN;CREB1 GO:0016032| viral reproduction CREB1;FYN GO:0042493| response to drug ABCB1;UGT1A1;CREB1;FYN GO:0010629| negative regulation of gene expression ESR1;OPRD1;FYN;CREB1 GO:0045087| innate immune response TLR4;FYN GO:0042981| regulation of apoptotic process FYN;CREB1;ESR1;PPIF GO:0070266| necroptosis TLR4;PPIF GO:0043066| negative regulation of apoptotic process ALB;PPIF GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;FYN GO:0045471| response to ethanol OPRM1;OPRK1;FYN;UGT1A1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FYN;TLR4 9201:[DB01183 DB00261] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;PDE3A;CREB1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PDE3A GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PDE3A GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0007165| signal transduction CREB1;TLR4;PDE3A;OPRK1;ESR1;OPRM1;OPRD1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE3A;OPRD1;OPRM1 9202:[DB01183 DB01942] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0042167| heme catabolic process UGT1A1;HMOX1 GO:0071363| cellular response to growth factor stimulus CREB1;NOS1;OPRD1 GO:0071456| cellular response to hypoxia HMOX1;OPRD1 GO:0006468| protein phosphorylation CTBP1;CREB1;CASK GO:0030154| cell differentiation CTBP1;FGF1;CREB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1;FGF1 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0000187| activation of MAPK activity FGF1;TLR4 GO:0055085| transmembrane transport SLC16A3;ABCB1;SLCO1A2 GO:0001666| response to hypoxia CREB1;NOS1;HMOX1 GO:0010033| response to organic substance CREB1;UGT1A1;CA2 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1;CTBP1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HMOX1 GO:0043627| response to estrogen stimulus ESR1;HMOX1;OPRK1;CA2 GO:0006351| transcription, DNA-dependent CREB1;CTBP1;ESR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HMOX1 GO:0008152| metabolic process GPHN;UGT1A1;CES1;CTBP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;FGF1;TLR4;CREB1;NOS1;CASK GO:0045672| positive regulation of osteoclast differentiation CREB1;CA2 GO:0043065| positive regulation of apoptotic process HMOX1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CTBP1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NOS1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;CTBP1 GO:0051607| defense response to virus OPRK1;RNASE1 GO:0042738| exogenous drug catabolic process NOS1;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;HMOX1;CTBP1;NOS1;GPHN;CYP2C8 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0016032| viral reproduction CREB1;CTBP1 GO:0035094| response to nicotine CREB1;HMOX1 9203:[DB01183 DB08447] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2E GO:0006954| inflammatory response PLA2G2E;TLR4 9204:[DB01183 DB08258] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;EPHX2;CYP2C8 GO:0008152| metabolic process EPHX2;CES1;UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0006954| inflammatory response EPHX2;TLR4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;EPHX2;CYP3A4 GO:0009636| response to toxin EPHX2;CES1 GO:0010628| positive regulation of gene expression TLR4;EPHX2 9205:[DB01183 DB13508] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13508|Cloranolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 9206:[DB01183 DB01007] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes CYP2C8;CYP3A4 common pathways GO:0006082| organic acid metabolic process CYP2C8 GO:0006629| lipid metabolic process CYP51A1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;CYP3A4;CYP2C19;CYP2C8 GO:0060065| uterus development CYP19A1;ESR1 GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0042737| drug catabolic process CYP3A4 GO:0006695| cholesterol biosynthetic process CYP51A1;CES1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP51A1;CYP2E1;CYP3A4;CYP19A1;CYP2C8;CYP2C19 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP2E1 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP51A1;CYP2E1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0002933| CYP3A4;CYP2C8 9207:[DB01183 DB06711] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1;ADRA1A GO:0042493| response to drug ABCB1;ADRA1A;CREB1;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A;ADRA1A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ESR1;OPRM1 GO:0007568| aging ADRA1A;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A;OPRK1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007165| signal transduction ADRA1A;OPRK1;ADRA2A;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;ADRA1A GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 9208:[DB01183 DB00513] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways GO:0008285| negative regulation of cell proliferation PLG;OPRM1 GO:0001666| response to hypoxia PLAT;CREB1 GO:0044267| cellular protein metabolic process ALB;PLG GO:0017144| drug metabolic process CYP3A4;UGT1A1;AOX1;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;AOX1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;LPA GO:0002576| platelet degranulation ALB;PLG 9209:[DB01183 DB03964] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03964|4-Hydroxy-Aconitate Ion ACO2 common genes common pathways GO:0001889| liver development ACO2;UGT1A1 GO:0008152| metabolic process ACO2;UGT1A1;CES1 9210:[DB01183 DB07666] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9211:[DB01183 DB04237] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways GO:0008152| metabolic process CES1;AMY1A;UGT1A1 GO:0007586| digestion UGT1A1;AMY1A 9212:[DB01183 DB03115] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways GO:0042981| regulation of apoptotic process MAP2K1;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;ESR1;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;MAP2K1;CREB1 GO:0006468| protein phosphorylation CREB1;MAP2K1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;MAP2K1 GO:0000187| activation of MAPK activity MAP2K1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;MAP2K1 9213:[DB01183 DB03924] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03924|5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone CSNK2A1 common genes common pathways GO:0048511| rhythmic process CSNK2A1;CREB1 GO:0006468| protein phosphorylation CREB1;CSNK2A1 GO:0007165| signal transduction CSNK2A1;OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;CSNK2A1 9214:[DB01183 DB02489] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 9215:[DB01183 DB13746] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes CYP2C8;CYP3A4 common pathways GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2C19 GO:0006082| organic acid metabolic process CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C19;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP2C19;CYP3A4 GO:0007268| synaptic transmission CACNB1;OPRK1;CACNB3;CACNA1G;CACNB4;CACNB2;OPRM1;OPRD1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration CACNA1A;OPRM1;ESR1;CACNA1C GO:0006810| transport CACNB3;CACNB1;ABCB1;CACNA1I;CACNB4 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0007165| signal transduction CREB1;TLR4;CACNA1I;OPRK1;OPRM1;OPRD1;ESR1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19;CYP2C9;UGT1A1 GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0070588| calcium ion transmembrane transport CACNA1A;CACNA1I;CACNA1F;CACNB1;CACNA1G;CACNA1S;CACNB3;CACNB4;CACNA1D;CACNA1C;CACNA1H;OPRM1;CACNB2 GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0055085| transmembrane transport CACNA1C;CACNA1D;SLCO1A2;CACNA1H;CACNA1F;CACNA1A;ABCB1;CACNA1I;CACNA1G;CACNA1S GO:0036378| CYP3A4 GO:0006811| ion transport CACNB2;SLCO1A2;CACNA1H;CACNA1C;CACNA1D;CACNB4;CACNB3;CACNA1G;CACNA1S;CACNB1;CACNA1F;CACNA1A;CACNA1I GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:1904646| TLR4;CACNA1A;CACNB1 GO:0042359| vitamin D metabolic process CYP3A4 9216:[DB01183 DB03802] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes ESR1 common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;OPRK1 GO:0060065| uterus development ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 9217:[DB01183 DB04365] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;OPRD1;OPRM1;CHRM1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRM1;CHRM3;CREB1;TLR4;OPRK1 GO:0007586| digestion CHRM3;UGT1A1 9218:[DB01183 DB01593] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes ESR1 common pathways GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;APP GO:0008152| metabolic process UGT1A1;ASPA;IDE;CPE;TPI1;CES1 GO:0071398| cellular response to fatty acid NME1;CREB1 GO:0043066| negative regulation of apoptotic process ALB;HDAC1;MMP9;MDM2;TP53;MT3;MGMT;SOD1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0060065| uterus development ESR1 GO:0002576| platelet degranulation SERPINA1;A2M;TF;ITIH4;SOD1;APLP2;A1BG;SERPINA3;FGA;KNG1;ITIH3;APOA1;ALB;AHSG;CLU;ORM2;ALDOA;SERPINA4;APP;FN1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0043065| positive regulation of apoptotic process SOD1;KNG1;TP73;MMP9;CREB1;APP;TP53;CLU GO:0050727| regulation of inflammatory response AHSG;TLR4;PGLYRP2;S100A9;S100A8;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0007626| locomotory behavior SOD1;OPRM1;APP;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;ESR1;TP73;APP;TP53;CREB1;HDAC4;TLR4;HDAC1 GO:0007218| neuropeptide signaling pathway GLRA1;OPRK1;CPE;OPRD1;OPRM1 GO:0050829| defense response to Gram-negative bacterium S100A7;IGHM;TLR4;APP;DCD GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0006629| lipid metabolic process APOA1;APOBR;CLU;APOE;APOL1;CYP3A4;C3;PON1 GO:0071260| cellular response to mechanical stimulus AGT;TLR4;HDAC4 GO:1990090| APP;CREB1 GO:0045087| innate immune response F12;C4BPB;APCS;S100A9;C8A;S100A8;APOL1;CFI;C3;C1QC;C5;C1S;IGHA1;C8G;C4B;PGLYRP2;C4BPA;APP;C1R;C8B;C1QB;CLU;S100A7;TLR4;IGHM;KRT16;FGA;CFH;FCN3;JCHAIN;CFB GO:0000122| negative regulation of transcription from RNA polymerase II promoter ENO1;TP73;MDM2;APP;TP53;HDAC4;HDAC1;HDAC8;PARP1;ESR1 GO:0042981| regulation of apoptotic process NME1;AGT;ESR1;TP73;CREB1;TP53 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0046889| positive regulation of lipid biosynthetic process INS;APOE;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0071294| cellular response to zinc ion MT1A;MT2A;GLRA1;CREB1;PARP1 GO:0042060| wound healing KRT6A;S100A8;OPRM1;GSN;INS;FN1;TP53;DSP GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter APOE;ESR1 GO:0032496| response to lipopolysaccharide S100A7;HDAC1;TLR4;UGT1A1;BDKRB1;OPRM1;S100A8 GO:0006695| cholesterol biosynthetic process APOA4;APOA1;CES1 GO:0051000| positive regulation of nitric-oxide synthase activity INS;ESR1;APOE GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0046330| positive regulation of JNK cascade TLR4;APP GO:0006351| transcription, DNA-dependent PARP1;ESR1;HDAC8;TP53;EEF1A1;HDAC1;CREB1;HDAC4;TP73;ENO1 GO:0019233| sensory perception of pain OPRM1;OPRD1;BDKRB1;OPRK1 GO:0000060| protein import into nucleus, translocation OPRD1;MT3 GO:0045471| response to ethanol OPRK1;TUFM;UGT1A1;TP53;MGMT;SOD1;S100A8;OPRM1;GSN GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;AGT;OPRK1 GO:0097190| apoptotic signaling pathway PDCD6;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA1 GO:0006955| immune response IL3;IGLV3-21;VTN;C8A;OPRD1;IGHA1;C1QC;C3;IGKV1-17;JCHAIN;OPRK1;C8B;C1R;TLR4 GO:0016032| viral reproduction SIVA1;HDAC1;IDE;CREB1;MDM2;TP53;APOA2;CFH;TP73 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;APP;JUP;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CLU;APP;S100A8;S100A9;INS;AGT GO:0071391| cellular response to estrogen stimulus MDM2;ESR1 GO:0060068| vagina development ESR1 GO:0006954| inflammatory response TLR4;HDAC4;KRT16;BDKRB1;KNG1;SERPINA3;KLKB1;C3;C5;S100A9;S100A8;C4B GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;ORM2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0043278| response to morphine OPRK1;MDM2;OPRM1 GO:0008542| visual learning APP;CREB1 GO:0048863| stem cell differentiation A2M;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0006953| acute-phase response ITIH4;APCS;SERPINA1;INS;FN1;UGT1A1;ORM2;AHSG;F2;SERPINA3 GO:0051924| regulation of calcium ion transport AGT;OPRD1 GO:0032760| positive regulation of tumor necrosis factor production CLU;TLR4;HDAC1 GO:0007595| lactation CREB1;NME1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;APOA2 GO:0045893| positive regulation of transcription, DNA-dependent TP53;HDAC4;CREB1;HDAC1;TP73;ESR1;AGT;MT3 GO:0007268| synaptic transmission OPRK1;GLRA1;APP;OPRM1;OPRD1 GO:0042493| response to drug NME1;MGMT;SOD1;TP73;ABCB1;APOA1;UGT1A1;APOA2;TP53;MDM2;CREB1;HDAC4;HDAC1 GO:0010629| negative regulation of gene expression APP;MDM2;CREB1;HDAC1;OPRD1;ESR1;AGT;HDAC8;NME1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0051607| defense response to virus FCN3;OPRK1 GO:0006355| regulation of transcription, DNA-dependent EEF1A1;HDAC1;CREB1;HDAC4;TP53;TP73;ENO1;ESR1;PARP1;INS;HDAC8 GO:1901215| APP;APOE;CREB1;MT3 GO:0042742| defense response to bacterium TLR4;DCD;S100A9;S100A8 GO:0043491| protein kinase B signaling cascade MDM2;CREB1;MT3 GO:0043687| post-translational protein modification C3;APLP2;P4HB;ITIH2;APOL1;TF;SERPINA1;CP;SERPIND1;FN1;APOE;APP;APOA2;APOA1;ALB;AHSG;FGA;KNG1 GO:0055114| oxidation-reduction process PDIA3;GAPDHS;PRDX1;CYP2C8;P4HB;SOD1;CYP3A4;CCS;CP;ADH1C GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0098869| S100A9;ALB;HBB;HBA1;APOE GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;HBB;CLU;APP;ESR1;OPRM1;INS;AGT GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1900273| APP;CREB1;INS GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0031100| organ regeneration APOA1;APOA2;UGT1A1 GO:0002376| immune system process FGA;FCN3;CFH;CFB;IGKV1-17;C8B;C1QB;C1R;CLU;TLR4;IGHM;C4B;C8G;C4BPA;PGLYRP2;C4BPB;S100A9;C8A;IGLV3-21;S100A8;C1QC;CFI;C3;IGHA1;C5;C1S GO:0006898| receptor-mediated endocytosis APOE;HBA1;HBB;HPR;JCHAIN;APOBR;APOA1;ALB;IGKV1-17;VTN;APOL1;IGLV3-21;CFI;IGHA1 GO:0032689| negative regulation of interferon-gamma production TLR4;PGLYRP2 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;APP GO:0007165| signal transduction OPRM1;OPRD1;ESR1;C3;JUP;BDKRB1;PDIA3;CREB1;TLR4;FGA;IGFALS;OPRK1 GO:0048545| response to steroid hormone stimulus MDM2;UGT1A1 GO:0050729| positive regulation of inflammatory response TLR4;AGT;S100A9;S100A8 GO:0008202| steroid metabolic process APOL1;CYP3A4;APOBR;APOA1;CYP2C8;APOE;UGT1A1 GO:0051384| response to glucocorticoid stimulus APOA2;UGT1A1;CPN1 GO:0032355| response to estradiol stimulus ESR1;AGT GO:0014002| astrocyte development MT3;S100A9;S100A8;TLR4 GO:0007186| G-protein coupled receptor signaling pathway BDKRB1;APOE;APP;APOA1;OPRK1;F2;KNG1;C5;C3;APLP2;OPRM1;OPRD1;INS;AGT GO:0050821| protein stabilization CPN2;APOA1;CLU;CREB1;MT3 GO:0071363| cellular response to growth factor stimulus CREB1;MDM2;OPRD1 GO:0032732| positive regulation of interleukin-1 production TLR4;HDAC1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;APP GO:0007568| aging GSN;SOD1;AGT;TP53;KRT16;CREB1;KRT14 GO:0002224| toll-like receptor signaling pathway S100A8;S100A9;FGA;TLR4 GO:0006810| transport ABCB1;TTR GO:0006338| chromatin remodeling HDAC4;HDAC1;ESR1 GO:0030154| cell differentiation TP53;CREB1;KRT6A;NME1 GO:0006468| protein phosphorylation APP;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007613| memory APP;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration AGT;ESR1;OPRM1;KNG1;BDKRB1;APP GO:0071456| cellular response to hypoxia P4HB;OPRD1;MT3;MDM2;TP53 GO:1904646| PARP1;TLR4;APP GO:0010628| positive regulation of gene expression INS;MT3;GSN;FN1;TLR4;CLU;MDM2;APP;TP53 GO:0001666| response to hypoxia MT3;CREB1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;AGT;FN1 GO:1903428| TLR4;HDAC4 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0032460| negative regulation of protein oligomerization INS;OPRD1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC4 GO:0016579| protein deubiquitination BRCC3;ESR1;MDM2;TP53 GO:0010033| response to organic substance SOD1;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation NME1;OPRM1;TP73;HDAC1;HDAC4;TP53;APP GO:1903223| APP;TLR4 GO:0043627| response to estrogen stimulus ESR1;APOA2;OPRK1;APOA1 GO:0007584| response to nutrient APOA1;UGT1A1 GO:0048511| rhythmic process TP53;CREB1;HDAC1 GO:0045922| negative regulation of fatty acid metabolic process INS;UGT1A1 GO:0034375| high-density lipoprotein particle remodeling APOA2;APOA4;APOE;ALB;APOA1 GO:0009636| response to toxin CES1;PON1;MGMT;MDM2 GO:0014070| response to organic cyclic compound MGMT;TP53;UGT1A1 GO:0006811| ion transport GLRA1;SLCO1A2;TF;CP GO:0007409| axonogenesis APP;CREB1 GO:0030879| mammary gland development NME1;CREB1 GO:0000187| activation of MAPK activity SOD1;C5;APP;TLR4;TP73 GO:0042220| response to cocaine OPRM1;OPRK1;MDM2 GO:0030855| epithelial cell differentiation KRT14;CES1 GO:0001895| retina homeostasis KRT1;TF;IGHA1;SOD1;PRDX1;ALB;JCHAIN GO:0008344| adult locomotory behavior APP;OPRD1 GO:0044267| cellular protein metabolic process APOE;APOA4;APOA2;APP;SEMG1;FN1;FGA;F2;KNG1;IGFALS;AHSG;ALB;APOA1;APOL1;ITIH2;P4HB;GSN;APCS;TF;APLP2;C3;CP;SERPIND1;TTR;INS;SERPINA1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;APOA1;PARP1 GO:0006366| transcription from RNA polymerase II promoter PARP1;ESR1;TP73;TP53;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MT3;S100A7;TLR4;APP;FGA GO:0055085| transmembrane transport APOA1;ABCB1;SLCO1A2 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 9219:[DB01183 DB00075] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CD3E;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction ESR1;OPRD1;FCGR2C;OPRM1;FCGR1A;OPRK1;TLR4;FCGR2B;CREB1 GO:0002376| immune system process C1S;C1QC;CD3G;C1QA;TLR4;CD3D;C1QB;C1R;CD3E;FCGR1A;FCGR2A;CD247 GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB GO:0007584| response to nutrient UGT1A1;CD3E GO:0010628| positive regulation of gene expression CD3E;TLR4 GO:1904646| TLR4;FCGR2B GO:0046330| positive regulation of JNK cascade TLR4;FCGR2B GO:0097190| apoptotic signaling pathway CD3E;TLR4 GO:0032729| positive regulation of interferon-gamma production TLR4;CD3E GO:0045087| innate immune response C1S;C1QC;C1QA;TLR4;C1QB;C1R;FCGR1A GO:0042981| regulation of apoptotic process CD3E;CREB1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CD3D;TLR4;CREB1;ESR1 GO:0009617| response to bacterium TLR4;FCGR2B GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;CD3E GO:0006955| immune response FCGR1A;OPRK1;FCGR3B;FCGR2B;TLR4;C1R;C1QC;FCGR2C;OPRD1;FCGR3A GO:0016032| viral reproduction CD247;CREB1;FCGR2B GO:0006954| inflammatory response FCGR2B;TLR4 9220:[DB01183 DB13893] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways GO:0008152| metabolic process ENPP1;UGT1A1;CES1 GO:0006629| lipid metabolic process CYP3A4;PLA2G10 GO:0006955| immune response OPRK1;TLR4;ENPP1;OPRD1 GO:0006898| receptor-mediated endocytosis ALB;ENPP1 GO:1990830| CREB1;PLA2G10 GO:0007411| axon guidance PLA2G10;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PLA2G10 9221:[DB01183 DB08387] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;PDE10A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE10A;OPRM1;OPRD1 GO:0008152| metabolic process UGT1A1;PDE10A;CES1 9222:[DB01183 DB00607] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes CYP3A4;ALB common pathways GO:0009822| alkaloid catabolic process CYP3A4 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0042359| vitamin D metabolic process CYP3A4 GO:0055085| transmembrane transport SLCO1A2;SLC22A6;ABCB1 GO:0036378| CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002933| CYP2C8;CYP3A4 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB GO:0009267| cellular response to starvation ALB GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 9223:[DB01183 DB05932] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;OPRD1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0010863| positive regulation of phospholipase C activity ESR1;FLT1 GO:0071456| cellular response to hypoxia VEGFA;OPRD1 GO:0030154| cell differentiation FLT1;VEGFA;CREB1 GO:0006468| protein phosphorylation FLT1;CREB1;FLT4 GO:0010628| positive regulation of gene expression TLR4;VEGFA GO:0001666| response to hypoxia VEGFA;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FLT4;TLR4;OPRM1;VEGFA GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0060749| mammary gland alveolus development ESR1;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:1900745| OPRK1;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;VEGFA;ESR1 GO:0002576| platelet degranulation VEGFA;ALB GO:0043066| negative regulation of apoptotic process VEGFA;ALB;FLT4 GO:0046330| positive regulation of JNK cascade TLR4;FLT4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0007595| lactation VEGFA;CREB1 GO:0010629| negative regulation of gene expression OPRD1;VEGFA;ESR1;CREB1 9224:[DB01183 DB06786] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06786|Halcinonide SMO;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway SMO;OPRD1;OPRM1;OPRK1 GO:0050821| protein stabilization CREB1;SMO GO:0040018| positive regulation of multicellular organism growth SMO;CREB1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;SMO;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0010628| positive regulation of gene expression SMO;TLR4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0043066| negative regulation of apoptotic process SMO;ALB GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;SMO;CREB1;TLR4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;SMO GO:0045893| positive regulation of transcription, DNA-dependent CREB1;SMO;ESR1 GO:0010629| negative regulation of gene expression SMO;ESR1;OPRD1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 9225:[DB01183 DB07513] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07513|7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE MAOB common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;TLR4;MAOB;UGT1A1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1;MAOB GO:0042493| response to drug CREB1;MAOB;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0009636| response to toxin MAOB;CES1 9226:[DB01183 DB13141] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2C8;CYP3A5;UGT1A1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP3A7;CYP3A4;CYP3A43 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP3A7;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 9227:[DB01183 DB05096] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05096|LY2140023 GRM2;GRM3 common genes common pathways GO:0007268| synaptic transmission OPRK1;GRM2;GRM3;OPRD1;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;GRM2;GRM3 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;GRM3;GRM2;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway GRM2;OPRK1;GRM3;OPRM1;OPRD1 9228:[DB01183 DB05343] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05343|Arundic acid S100B common genes common pathways GO:0007409| axonogenesis S100B;CREB1 GO:0007613| memory CREB1;S100B GO:0071456| cellular response to hypoxia OPRD1;S100B GO:0051384| response to glucocorticoid stimulus UGT1A1;S100B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;S100B GO:0045087| innate immune response TLR4;S100B GO:0043065| positive regulation of apoptotic process CREB1;S100B 9229:[DB01183 DB00134] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0002376| immune system process MSRB1;TLR4 GO:0009267| cellular response to starvation MARS;GLUL;ALB GO:0036120| CREB1;MARS GO:0001666| response to hypoxia CREB1;MTHFR GO:1990830| MAT2A;CREB1 GO:0055085| transmembrane transport SLCO1A2;SLC16A10;ABCB1 GO:0045087| innate immune response TLR4;MSRB1 GO:0008152| metabolic process UGT1A1;MTHFR;CES1 GO:0055114| oxidation-reduction process CYP2C8;MSRB1;MSRB2;MSRA;MTRR;CYP3A4;MTHFR GO:0006355| regulation of transcription, DNA-dependent ESR1;MSRB2;CREB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;MTHFR 9230:[DB01183 DB04973] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04973|LErafAON RAF1 common genes common pathways GO:0042060| wound healing OPRM1;RAF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;ESR1;TLR4;CREB1 GO:0043066| negative regulation of apoptotic process ALB;RAF1 GO:0042981| regulation of apoptotic process CREB1;ESR1;RAF1 GO:0006468| protein phosphorylation CREB1;RAF1 GO:0030154| cell differentiation RAF1;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation RAF1;OPRD1 GO:0007165| signal transduction ESR1;RAF1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;RAF1 GO:0001666| response to hypoxia CREB1;RAF1 GO:0008285| negative regulation of cell proliferation RAF1;OPRM1 9231:[DB01183 DB05895] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05895|HGS-TR2J TNFRSF10B common genes common pathways GO:0006954| inflammatory response TLR4;TNFRSF10B GO:0006955| immune response OPRD1;TNFRSF10B;TLR4;OPRK1 GO:0042981| regulation of apoptotic process ESR1;TNFRSF10B;CREB1 GO:0071260| cellular response to mechanical stimulus TLR4;TNFRSF10B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFRSF10B;TLR4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;TNFRSF10B;OPRM1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;TNFRSF10B;ESR1;OPRD1;OPRM1 9232:[DB01183 DB02943] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways GO:0098869| ALB;GSTA1 GO:0030855| epithelial cell differentiation CES1;GSTA1 GO:0008152| metabolic process UGT1A1;GSTA1;CES1 9233:[DB01183 DB07280] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 9234:[DB01183 DB03182] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 9235:[DB01183 DB02021] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;AKR1B1;AKR1B10;CYP2C8 GO:0007586| digestion AKR1B10;UGT1A1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0010033| response to organic substance UGT1A1;AKR1B1;CREB1 GO:0008202| steroid metabolic process CYP2C8;AKR1B10;UGT1A1;CYP3A4 9236:[DB01183 DB02164] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02164|N-Sulfo-Flavin Mononucleotide HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;HAO1;CYP3A4 9237:[DB01183 DB04616] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways 9238:[DB01183 DB13923] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13923|Emicizumab F9;F10 common genes common pathways 9239:[DB01183 DB00112] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0002376| immune system process C1R;C1QB;TLR4;FCGR2A;FCGR1A;C1QC;C1QA GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;OPRD1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;FCGR2C;OPRK1;FCGR1A;FCGR2B;CREB1;TLR4 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0030154| cell differentiation CREB1;VEGFA GO:0071456| cellular response to hypoxia OPRD1;VEGFA GO:0001666| response to hypoxia VEGFA;CREB1 GO:0010628| positive regulation of gene expression TLR4;VEGFA GO:1904646| FCGR2B;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;VEGFA GO:0030855| epithelial cell differentiation VEGFA;CES1 GO:0002576| platelet degranulation ALB;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;VEGFA;ESR1 GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0045087| innate immune response C1R;C1QB;TLR4;FCGR1A;C1QC;C1QA GO:0060749| mammary gland alveolus development ESR1;VEGFA GO:1900745| VEGFA;OPRK1 GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0046330| positive regulation of JNK cascade TLR4;FCGR2B GO:0006954| inflammatory response FCGR2B;TLR4 GO:0006955| immune response C1QC;OPRD1;FCGR2C;FCGR3A;FCGR2B;FCGR3B;TLR4;C1R;OPRK1;FCGR1A GO:0016032| viral reproduction CREB1;FCGR2B GO:0007595| lactation CREB1;VEGFA GO:0010629| negative regulation of gene expression OPRD1;VEGFA;ESR1;CREB1 GO:0009617| response to bacterium TLR4;FCGR2B 9240:[DB01183 DB05771] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05771|LLL-3348 IL10 common genes common pathways GO:0007568| aging CREB1;IL10 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;IL10 GO:0051384| response to glucocorticoid stimulus IL10;UGT1A1 GO:0043032| positive regulation of macrophage activation TLR4;IL10 GO:0045019| negative regulation of nitric oxide biosynthetic process IL10;OPRM1 GO:0035729| cellular response to hepatocyte growth factor stimulus IL10;CREB1 GO:0032715| negative regulation of interleukin-6 production TLR4;IL10 GO:0032720| negative regulation of tumor necrosis factor production IL10;TLR4 GO:0032689| negative regulation of interferon-gamma production TLR4;IL10 GO:0032868| response to insulin stimulus IL10;OPRK1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;IL10;OPRK1 GO:0010033| response to organic substance UGT1A1;IL10;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;IL10 GO:0014823| response to activity IL10;CREB1 GO:0045348| positive regulation of MHC class II biosynthetic process TLR4;IL10 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;IL10;TLR4 GO:0043066| negative regulation of apoptotic process ALB;IL10 GO:0071222| cellular response to lipopolysaccharide OPRK1;IL10;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL10;CREB1;TLR4;ESR1 GO:0042742| defense response to bacterium TLR4;IL10 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;IL10 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;IL10 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;IL10 GO:0006955| immune response TLR4;IL10;OPRK1;OPRD1 GO:0006954| inflammatory response IL10;TLR4 9241:[DB01183 DB06458] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06458|Remacemide CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 9242:[DB01183 DB07333] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07333|N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE KDR common genes common pathways GO:0016032| viral reproduction KDR;CREB1 GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0010629| negative regulation of gene expression CREB1;KDR;ESR1;OPRD1 GO:0043066| negative regulation of apoptotic process KDR;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;TLR4 GO:0006468| protein phosphorylation CREB1;KDR GO:0030154| cell differentiation KDR;CREB1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR 9243:[DB01183 DB07840] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways GO:0010629| negative regulation of gene expression CREB1;OPRD1;FGFR1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;FGFR1 GO:0006351| transcription, DNA-dependent CREB1;FGFR1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;ESR1 GO:0006468| protein phosphorylation FGFR1;CREB1 GO:0010863| positive regulation of phospholipase C activity ESR1;FGFR1 9244:[DB01183 DB05235] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;THRA;ESR1 GO:0043401| steroid hormone mediated signaling pathway THRA;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;THRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter CRYM;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;THRA;CREB1;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CRYM GO:0006355| regulation of transcription, DNA-dependent THRA;CREB1;ESR1 GO:0060509| Type I pneumocyte differentiation THRA;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter THRA;ESR1 GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process ALB;TTR GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1;THRA 9245:[DB01183 DB01295] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:1904646| TLR4;ADRB2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0007165| signal transduction ADRB2;ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;ADRA1A;ADRB1 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ESR1;OPRM1 GO:0007568| aging CREB1;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRA1A;ADRB1;ADRB2;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;ADRA1A;ABCB1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CES1;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1;ADRA1A GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 9246:[DB01183 DB08164] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9247:[DB01183 DB01336] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways GO:0035094| response to nicotine CHRNA2;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0007165| signal transduction OPRD1;OPRM1;CHRM2;ESR1;CHRNA2;TLR4;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CHRM2;OPRK1 9248:[DB01183 DB06655] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 GO:0007165| signal transduction GLP1R;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GLP1R;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;ESR1;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRM1;MME;OPRD1 9249:[DB01183 DB05268] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05268|iCo-007 RAF1 common genes common pathways GO:0001666| response to hypoxia RAF1;CREB1 GO:0008285| negative regulation of cell proliferation RAF1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;RAF1;TLR4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;RAF1;OPRD1;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;RAF1 GO:0006468| protein phosphorylation CREB1;RAF1 GO:0030154| cell differentiation RAF1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RAF1;TLR4;CREB1 GO:0043066| negative regulation of apoptotic process ALB;RAF1 GO:0042981| regulation of apoptotic process CREB1;RAF1;ESR1 GO:0042060| wound healing RAF1;OPRM1 9250:[DB01183 DB04539] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes ALB common pathways GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0060065| uterus development CYP19A1;ESR1 GO:0043066| negative regulation of apoptotic process ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0030879| mammary gland development CYP19A1;CREB1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB 9251:[DB01183 DB00162] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes ALB common pathways GO:0007568| aging CREB1;CYP1A1;APOD GO:0043069| negative regulation of programmed cell death ALB GO:0021983| pituitary gland development ALDH1A2;CREB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP1A1;UGT1A1;CYP2C8;DHRS4 GO:0032355| response to estradiol stimulus ALDH1A2;ESR1 GO:0051659| maintenance of mitochondrion location ALB GO:0017144| drug metabolic process CYP3A4;CYP1A1;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP1A1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;HPGDS GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0009636| response to toxin CES1;CYP1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0042573| retinoic acid metabolic process CYP26A1;ALDH1A2;UGT1A1;LRAT;ALDH1A3 GO:0010033| response to organic substance UGT1A1;CYP1A1;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;ALDH1A2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0010628| positive regulation of gene expression ALDH1A2;TLR4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:1990830| LRAT;CREB1 GO:0001889| liver development ALDH1A2;UGT1A1;CYP1A1 GO:0045471| response to ethanol OPRK1;UGT1A1;RBP4;OPRM1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;CYP1A1 GO:0006629| lipid metabolic process RBP3;APOD;CYP3A4;HPGDS GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0008152| metabolic process CES1;ALDH1A1;UGT1A1;ALDH1A3;ALDH1A2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP26A1;CYP2C8 GO:0060065| uterus development ESR1;RBP4 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043065| positive regulation of apoptotic process ALDH1A3;CREB1;ALDH1A2 GO:0007626| locomotory behavior OPRK1;ALDH1A3;HPGDS;OPRM1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1A1;ALDH1A3;RDH12;DHRS4;CYP2C8;ALDH1A2;RDH5;RDH8;CYP3A4;RDH14;CYP26A1;RDH11;RDH13;ALDH1A1;RETSAT;DHRS3 GO:0032094| response to food CYP1A1;OPRM1 GO:0042493| response to drug APOD;ABCB1;CREB1;CYP1A1;UGT1A1 GO:0060068| vagina development ESR1;RBP4 9252:[DB01183 DB05372] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05372|CP-945598 CNR1 common genes common pathways GO:0035094| response to nicotine CREB1;CNR1 GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;CNR1;UGT1A1;TLR4 GO:0045471| response to ethanol UGT1A1;OPRK1;CNR1;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;CNR1 GO:0043065| positive regulation of apoptotic process CNR1;CREB1 GO:0042220| response to cocaine OPRK1;CNR1;OPRM1 GO:0007584| response to nutrient UGT1A1;CNR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CNR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;CNR1 GO:0007613| memory CREB1;CNR1 GO:0007568| aging CNR1;CREB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;CNR1;ESR1;OPRD1;OPRM1 9253:[DB01183 DB07908] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways GO:0050821| protein stabilization PFN1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PFN1 9254:[DB01183 DB06586] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06586|Cetilistat PNLIP common genes common pathways GO:0006629| lipid metabolic process PNLIP;CYP3A4 9255:[DB01183 DB02684] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02684|5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine EPRS common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;EPRS 9256:[DB01183 DB00174] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0043066| negative regulation of apoptotic process ASNS;ALB GO:0001889| liver development UGT1A1;ASNS GO:0016032| viral reproduction SLC1A5;CREB1 GO:0032870| cellular response to hormone stimulus UGT1A1;ASNS GO:0006811| ion transport SLCO1A2;SLC38A3 GO:0009636| response to toxin CES1;ASNS GO:0055085| transmembrane transport SLC38A3;SLC16A10;SLCO1A2;ABCB1 9257:[DB01183 DB04873] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04873|Piboserod HTR4 common genes common pathways GO:0007268| synaptic transmission HTR4;OPRM1;OPRD1;OPRK1 GO:0007165| signal transduction OPRM1;HTR4;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;HTR4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;HTR4 9258:[DB01183 DB01154] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0055085| transmembrane transport KCNJ11;SLCO1A2;ABCB1 GO:0036378| CYP3A4 GO:0006811| ion transport GABRA1;KCNJ11;KCNJ8;SLCO1A2 GO:0002933| CYP2C8;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4;CYP2E1 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0006810| transport GABRA1;ABCB1 GO:0032355| response to estradiol stimulus ESR1;KCNJ11 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4;CYP2E1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2C9 GO:0051607| defense response to virus OPRK1;KCNJ8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;KCNJ11;CYP2E1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1;UGT1A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;KCNJ8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 9259:[DB01183 DB07046] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways GO:0006468| protein phosphorylation MAP2K1;CREB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;MAP2K1 GO:0000187| activation of MAPK activity MAP2K1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;MAP2K1;OPRM1 GO:0010628| positive regulation of gene expression TLR4;MAP2K1 GO:0008285| negative regulation of cell proliferation OPRM1;MAP2K1 GO:0042981| regulation of apoptotic process CREB1;MAP2K1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;MAP2K1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1;MAP2K1 9260:[DB01183 DB02983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02983|Para-Mercury-Benzenesulfonic Acid CLC;ESR2 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;ESR2 GO:0007165| signal transduction OPRK1;ESR2;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;CREB1;TLR4 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 9261:[DB01183 DB01031] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01031|Ethinamate CA1;CA2 common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0043627| response to estrogen stimulus OPRK1;CA2;ESR1 GO:0010033| response to organic substance CA2;CREB1;UGT1A1 GO:0045672| positive regulation of osteoclast differentiation CA2;CREB1 GO:2001225| regulation of chloride transport ABCB1;CA2 9262:[DB01183 DB06779] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0042060| wound healing HPSE;OPRM1 GO:0032496| response to lipopolysaccharide SELP;OPRM1;TFPI;UGT1A1;TLR4 GO:1900745| OPRK1;VEGFA GO:0010572| positive regulation of platelet activation SELP;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0060749| mammary gland alveolus development ESR1;VEGFA GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0002576| platelet degranulation ALB;VEGFA;SELP GO:0071222| cellular response to lipopolysaccharide TLR4;TFPI;OPRK1 GO:0050829| defense response to Gram-negative bacterium TLR4;SELP GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;VEGFA;CREB1;TLR4 GO:0043687| post-translational protein modification ALB;SERPINC1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1;VEGFA GO:0007595| lactation VEGFA;SERPINC1;CREB1 GO:0006954| inflammatory response SELP;TLR4 GO:0030154| cell differentiation VEGFA;CREB1 GO:0071456| cellular response to hypoxia VEGFA;OPRD1 GO:0032355| response to estradiol stimulus ESR1;TFPI GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0044267| cellular protein metabolic process ALB;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade VEGFA;OPRM1;TLR4 GO:0007584| response to nutrient UGT1A1;SERPINC1 GO:0001666| response to hypoxia CREB1;VEGFA GO:0010628| positive regulation of gene expression VEGFA;TLR4 9263:[DB01183 DB11937] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways GO:0048511| rhythmic process CREB1;AHR GO:0006366| transcription from RNA polymerase II promoter CREB1;AHR;ESR1 GO:0009636| response to toxin CES1;AHR GO:0007165| signal transduction ESR1;OPRM1;OPRD1;GPR35;OPRK1;CREB1;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration GPR35;ESR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway GPR35;OPRK1;OPRM1;OPRD1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AHR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AHR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AHR;CREB1;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;AHR;CES1;CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;AHR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AHR 9264:[DB01183 DB06159] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06159|Rubitecan TOP1 common genes common pathways GO:0048511| rhythmic process CREB1;TOP1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0042493| response to drug TOP1;CREB1;UGT1A1;ABCB1 GO:0016032| viral reproduction TOP1;CREB1 GO:0007623| circadian rhythm CREB1;TOP1 9265:[DB01183 DB05501] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0071222| cellular response to lipopolysaccharide OPRK1;CCR5;TLR4 GO:0006954| inflammatory response CCR5;TLR4;CXCR4 GO:0006955| immune response OPRD1;OPRK1;TLR4;CCR5 GO:0016032| viral reproduction CREB1;CCR5;CXCR4 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;CXCR4;CCR5 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CXCR4;CCR5;OPRD1;OPRM1 GO:0007165| signal transduction CXCR4;OPRK1;CCR5;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0000187| activation of MAPK activity TLR4;CXCR4 GO:0007411| axon guidance CREB1;CXCR4 GO:0001666| response to hypoxia CXCR4;CREB1 9266:[DB01183 DB07771] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07771|[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID KRAS;FNTA;FNTB common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity KRAS;TLR4 GO:0008542| visual learning CREB1;KRAS GO:0001889| liver development KRAS;UGT1A1 GO:0051000| positive regulation of nitric-oxide synthase activity KRAS;ESR1 GO:0010628| positive regulation of gene expression TLR4;KRAS GO:0007411| axon guidance CREB1;KRAS GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CREB1 GO:0007165| signal transduction KRAS;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0051384| response to glucocorticoid stimulus KRAS;UGT1A1 9267:[DB01183 DB03839] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03839|D-Tyrosine SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLC16A10;ABCB1 9268:[DB01183 DB02400] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02400|5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0007568| aging CREB1;NQO1 GO:0032355| response to estradiol stimulus ESR1;NQO1 GO:0014070| response to organic cyclic compound UGT1A1;NQO1 GO:0009636| response to toxin NQO1;CES1 GO:0007584| response to nutrient UGT1A1;NQO1 GO:0045471| response to ethanol OPRM1;OPRK1;NQO1;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP2C8;CYP3A4;CES1 GO:0055114| oxidation-reduction process NQO1;CYP2C8;CYP3A4 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 9269:[DB01183 DB06862] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways GO:0001666| response to hypoxia CREB1;CASP3 GO:0010033| response to organic substance CASP3;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CASP3 GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0032355| response to estradiol stimulus CASP3;ESR1 GO:0035094| response to nicotine CREB1;CASP3 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CASP3 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;CREB1 GO:0042060| wound healing CASP3;OPRM1 GO:0032496| response to lipopolysaccharide CASP3;OPRM1;UGT1A1;TLR4 GO:0097190| apoptotic signaling pathway CASP3;TLR4 9270:[DB01183 DB06492] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06492|Mirococept C3 common genes common pathways GO:0002376| immune system process C3;TLR4 GO:0007165| signal transduction ESR1;C3;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway C3;OPRM1;OPRD1;OPRK1 GO:0044267| cellular protein metabolic process ALB;C3 GO:0045087| innate immune response TLR4;C3 GO:0006629| lipid metabolic process C3;CYP3A4 GO:0006954| inflammatory response C3;TLR4 GO:0006955| immune response OPRK1;TLR4;OPRD1;C3 GO:0043687| post-translational protein modification ALB;C3 9271:[DB01183 DB01426] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0002576| platelet degranulation ALB;ORM1 GO:0006954| inflammatory response ORM1;TLR4 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;ORM1 GO:0032720| negative regulation of tumor necrosis factor production ORM1;TLR4 GO:0032715| negative regulation of interleukin-6 production ORM1;TLR4 GO:0006811| ion transport SLCO1A2;SCN5A GO:0055085| transmembrane transport SCN5A;SLCO1A2;ABCB1 9272:[DB01183 DB04551] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO2A1;ALB;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLCO2A1 GO:0007584| response to nutrient PKLR;UGT1A1 GO:0001666| response to hypoxia CREB1;PKLR GO:0008152| metabolic process UGT1A1;PKLR;CES1 9273:[DB01183 DB12520] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12520|Plozalizumab CCR2 common genes common pathways GO:0042535| positive regulation of tumor necrosis factor biosynthetic process CCR2;TLR4 GO:0006954| inflammatory response CCR2;TLR4 GO:0016032| viral reproduction CREB1;CCR2 GO:0006955| immune response OPRD1;CCR2;TLR4;OPRK1 GO:0019233| sensory perception of pain CCR2;OPRM1;OPRD1;OPRK1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;CCR2 GO:0032729| positive regulation of interferon-gamma production TLR4;CCR2 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;CCR2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;CCR2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CCR2;OPRK1 GO:0050729| positive regulation of inflammatory response CCR2;TLR4 9274:[DB01183 DB07558] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways GO:0043687| post-translational protein modification PSMA7;ALB GO:0016032| viral reproduction PSMA7;CREB1 GO:0055085| transmembrane transport SLCO1A2;PSMA7;ABCB1 GO:0016579| protein deubiquitination ESR1;PSMA7 9275:[DB01183 DB08830] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLC2A1;ABCB1 GO:0032868| response to insulin stimulus SLC2A1;OPRK1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0071260| cellular response to mechanical stimulus TLR4;SLC2A1 9276:[DB01183 DB07958] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;TLR4 GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 9277:[DB01183 DB00462] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 GO:0007165| signal transduction OPRD1;OPRM1;CHRM2;ESR1;CHRM1;CHRM3;TLR4;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway CHRM2;CHRM1;OPRD1;OPRM1;OPRK1;CHRM3 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRM1;OPRD1 9278:[DB01183 DB04850] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2C8 GO:0015711| organic anion transport SLCO1B1;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B1;ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;ALB GO:0055085| transmembrane transport ABCB1;SLCO1B1;SLCO1A2 GO:0006811| ion transport SLCO1B1;SLCO1A2 9279:[DB01183 DB05142] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05142|ND7001 PDE2A;PDE2A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE2A;OPRD1;OPRM1 GO:0050729| positive regulation of inflammatory response PDE2A;TLR4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;PDE2A;OPRK1 GO:0070588| calcium ion transmembrane transport PDE2A;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;ESR1 GO:0071260| cellular response to mechanical stimulus PDE2A;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PDE2A GO:0008152| metabolic process UGT1A1;PDE2A;CES1 9280:[DB01183 DB06266] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0055085| transmembrane transport CFTR;ABCB1;SLCO1A2 GO:0006811| ion transport SLCO1A2;CFTR GO:0016579| protein deubiquitination ESR1;CFTR GO:0006695| cholesterol biosynthetic process CFTR;CES1 GO:0008152| metabolic process CES1;UGT1A1;HK1 GO:0050718| positive regulation of interleukin-1 beta secretion HK1;TLR4 9281:[DB01183 DB04724] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04724|(S)-2-((S)-3-ISOBUTYL-2,5-DIOXO-4-QUINOLIN-3-YLMETHYL-[1,4]DIAZEPAN-1YL)-N-METHYL-3-NAPHTALEN-2-YL-PROPIONAMIDE ITGAL common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;ITGAL;OPRM1;OPRD1 GO:0006954| inflammatory response TLR4;ITGAL 9282:[DB01183 DB04858] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;CYP3A4;CYP2C8 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol UGT1A1;OPRK1;CYP2E1;OPRM1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2E1 9283:[DB01183 DB03348] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03348|Huperzine B ACHE common genes common pathways 9284:[DB01183 DB05930] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05930|SB-559448 MPL common genes common pathways 9285:[DB01183 DB01864] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways GO:0001889| liver development UGT1A1;ARF6 GO:0043687| post-translational protein modification RAB11A;ALB GO:0030154| cell differentiation CREB1;ARF6 9286:[DB01183 DB07528] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07528|3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR GO:0006468| protein phosphorylation CREB1;KDR GO:0030154| cell differentiation CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;KDR GO:0016032| viral reproduction KDR;CREB1 GO:0043066| negative regulation of apoptotic process KDR;ALB 9287:[DB01183 DB05457] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05457|OSI-7904L TYMS common genes common pathways GO:0042493| response to drug UGT1A1;TYMS;CREB1;ABCB1 GO:0045471| response to ethanol OPRM1;OPRK1;TYMS;UGT1A1 GO:0007623| circadian rhythm CREB1;TYMS GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0009636| response to toxin CES1;TYMS GO:0007568| aging TYMS;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS 9288:[DB01183 DB02032] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 9289:[DB01183 DB00668] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042742| defense response to bacterium TNF;TLR4 GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0055114| oxidation-reduction process CYP2C9;MAOB;CYP2C8;CYP3A4;MAOA GO:0042493| response to drug ABCB1;ADRA1A;CREB1;COMT;MAOB;UGT1A1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;TNF;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0045893| positive regulation of transcription, DNA-dependent CREB1;TNF;ESR1 GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0006954| inflammatory response TLR4;TNF GO:0006955| immune response OPRD1;OPRK1;TNF;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;ESR1 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0045471| response to ethanol MAOB;UGT1A1;OPRK1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;OPRD1;OPRM1;ESR1;ADRA1A;OPRK1;ADRA1D GO:0097190| apoptotic signaling pathway TNF;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;MAOB;COMT GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0032729| positive regulation of interferon-gamma production TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0043065| positive regulation of apoptotic process TNF;CREB1 GO:0050727| regulation of inflammatory response TLR4;TNF;ESR1 GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TNF;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TNF GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TNF GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ADRA1A;TNF;TLR4 GO:0055085| transmembrane transport SLC22A1;SLC22A2;ABCB1;SLCO1A2 GO:0036378| CYP3A4 GO:0000187| activation of MAPK activity ADRA2B;TLR4;TNF GO:0006811| ion transport SLC22A1;SLC22A2;SLCO1A2 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;COMT;OPRK1 GO:0002933| CYP3A4;CYP2C8 GO:0009636| response to toxin CES1;MAOB GO:0014070| response to organic cyclic compound COMT;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;COMT;OPRK1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0010033| response to organic substance TNF;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0010628| positive regulation of gene expression TNF;TLR4 GO:1904646| TLR4;ADRB2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;OPRM1;ESR1;ADRA1A;ADRA1D GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 GO:0007568| aging ADRA1A;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;OPRK1;ADRA1A;ADRB1;ADRA1D;ADRA1B;ADRA2B;ADRB2;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0007165| signal transduction ADRA1D;TLR4;CREB1;ADRB1;ADRA1A;OPRK1;ADRA2A;OPRD1;OPRM1;ADRB2;ADRA2B;ESR1;ADRA1B GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2C8;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0015711| organic anion transport SLC22A2;SLC22A1;SLCO1A2 GO:0032722| positive regulation of chemokine production TNF;TLR4 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production TNF;TLR4 9290:[DB01183 DB04489] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 9291:[DB01183 DB11081] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11081|Aluminum chloride GLUD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GLUD1;CYP2C8 9292:[DB01183 DB06011] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06011|AMG-222 DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 9293:[DB01183 DB05395] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05395|Amibegron ADRB3 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB3;OPRM1;OPRD1 GO:0007568| aging CREB1;ADRB3 GO:0006898| receptor-mediated endocytosis ALB;ADRB3 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;ADRB3;OPRK1 GO:0042755| eating behavior OPRD1;OPRM1;ADRB3;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRD1;OPRM1 9294:[DB01183 DB00699] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00699|Nicergoline ADRA1A;CYP2D6 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;ADRA1A GO:0007568| aging ADRA1A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;OPRK1;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction TLR4;CREB1;ADRA1A;OPRK1;OPRD1;OPRM1;ESR1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ADRA1A;TLR4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;OPRM1;OPRD1;ESR1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4;CES1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ADRA1A;ABCB1 9295:[DB01183 DB01171] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01171|Moclobemide MAOA;MAOA;MAOB;MAOB;MAOA;MAOB;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2C9;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0097267| CYP2C9;CYP2C19;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A4 GO:0009636| response to toxin MAOB;CES1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;MAOB;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C19 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0045471| response to ethanol UGT1A1;MAOB;OPRK1;OPRM1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C19;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0042493| response to drug CREB1;MAOB;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2D6;CYP2C19;CYP2C8;MAOB;CYP2C9 9296:[DB01183 DB05678] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05678|SLx-4090 MTTP common genes common pathways GO:0006629| lipid metabolic process MTTP;CYP3A4 9297:[DB01183 DB01017] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0007595| lactation VEGFA;CREB1 GO:0050718| positive regulation of interleukin-1 beta secretion CASP1;TLR4 GO:0035094| response to nicotine CASP3;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IL1B GO:0006954| inflammatory response ALOX5;TLR4;IL1B GO:0006955| immune response OPRD1;TLR4;OPRK1;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;IL1B GO:0009617| response to bacterium CASP1;TLR4 GO:0055114| oxidation-reduction process ALOX5;CYCS;CYP3A4;CYP2C8 GO:0043491| protein kinase B signaling cascade CREB1;IL1B GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CASP3 GO:0010629| negative regulation of gene expression VEGFA;OPRD1;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;IL1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0042981| regulation of apoptotic process CREB1;CASP1;ESR1 GO:0060749| mammary gland alveolus development ESR1;VEGFA GO:1900745| OPRK1;IL1B;VEGFA GO:0071260| cellular response to mechanical stimulus IL1B;TLR4;CASP1 GO:0043065| positive regulation of apoptotic process MMP9;CREB1;CASP3 GO:0002576| platelet degranulation VEGFA;ALB GO:0050727| regulation of inflammatory response ESR1;TLR4;CASP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;CREB1;TLR4;ESR1;VEGFA GO:0071222| cellular response to lipopolysaccharide OPRK1;CASP1;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;IL1B GO:0043066| negative regulation of apoptotic process VEGFA;CASP3;MMP9;ALB GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;IL1B GO:0097190| apoptotic signaling pathway TLR4;CASP3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;CASP1;TLR4 GO:0046330| positive regulation of JNK cascade TLR4;IL1B GO:0042060| wound healing OPRM1;CASP3 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0032496| response to lipopolysaccharide IL1B;CASP1;TLR4;UGT1A1;CASP3;OPRM1 GO:0032729| positive regulation of interferon-gamma production TLR4;IL1B GO:0008285| negative regulation of cell proliferation IL1B;OPRM1 GO:0010033| response to organic substance CASP3;UGT1A1;CREB1 GO:0010628| positive regulation of gene expression TLR4;IL1B;VEGFA GO:0001666| response to hypoxia VEGFA;CASP3;CASP1;CREB1 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;SLC22A11;SLC22A7;SLC22A6;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;VEGFA;OPRM1 GO:0030855| epithelial cell differentiation VEGFA;CES1 GO:0000187| activation of MAPK activity TLR4;IL1B GO:0006811| ion transport SLCO1A2;SLC22A8;SLC22A11;SLC22A7 GO:0014070| response to organic cyclic compound UGT1A1;CASP3 GO:0009636| response to toxin CES1;SLC22A8 GO:0007165| signal transduction CASP1;TLR4;CREB1;IL1B;OPRK1;ESR1;OPRD1;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA GO:0015711| organic anion transport SLC22A11;SLC22A7;SLCO1A2;SLC22A6 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0032757| positive regulation of interleukin-8 production IL1B;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;IL1B;OPRM1;ESR1 GO:0032755| positive regulation of interleukin-6 production TLR4;IL1B GO:0030154| cell differentiation VEGFA;CREB1 GO:0071456| cellular response to hypoxia OPRD1;VEGFA GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0032355| response to estradiol stimulus CASP3;ESR1 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1A2;SLC22A8;SLC22A11;SLC22A7 9298:[DB01183 DB03283] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03283|beta-L-fucose ACHE common genes common pathways 9299:[DB01183 DB01728] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01728|3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-Glycerol RHO common genes common pathways GO:0007165| signal transduction CREB1;TLR4;RHO;OPRK1;ESR1;OPRM1;OPRD1 GO:0006468| protein phosphorylation CREB1;RHO GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;RHO 9300:[DB01183 DB02391] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PNP GO:0006955| immune response OPRD1;PNP;TLR4;OPRK1 9301:[DB01183 DB02497] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02497|L-Alpha-Glycerophosphorylserine ANXA5 common genes common pathways GO:0043086| negative regulation of catalytic activity UGT1A1;ANXA5 GO:0043066| negative regulation of apoptotic process ANXA5;ALB GO:0002576| platelet degranulation ALB;ANXA5 GO:0010033| response to organic substance ANXA5;CREB1;UGT1A1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;ANXA5 9302:[DB01183 DB05478] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05478|Pradefovir Mesylate CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 9303:[DB01183 DB01178] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01178|Chlormezanone TSPO common genes common pathways GO:0043065| positive regulation of apoptotic process CREB1;TSPO GO:0071222| cellular response to lipopolysaccharide TSPO;TLR4;OPRK1 GO:0071294| cellular response to zinc ion CREB1;TSPO GO:0042493| response to drug TSPO;UGT1A1;CREB1;ABCB1 GO:0032720| negative regulation of tumor necrosis factor production TSPO;TLR4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;TSPO;OPRD1;OPRM1 GO:0045019| negative regulation of nitric oxide biosynthetic process TSPO;OPRM1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;TSPO GO:0007568| aging CREB1;TSPO GO:0006811| ion transport TSPO;SLCO1A2 9304:[DB01183 DB03214] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;IL4I1;CYP2C8 9305:[DB01183 DB06987] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways GO:0002376| immune system process TLR4;LTF GO:0001895| retina homeostasis LTF;ALB GO:0044267| cellular protein metabolic process ALB;LTF GO:0006811| ion transport LTF;SLCO1A2 GO:0045087| innate immune response LTF;TLR4 GO:0006629| lipid metabolic process CYP3A4;PLA2G2E GO:0050829| defense response to Gram-negative bacterium LTF;TLR4 GO:0043066| negative regulation of apoptotic process ALB;LTF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;LTF GO:0006351| transcription, DNA-dependent CREB1;ESR1;LTF GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;LTF GO:0006954| inflammatory response TLR4;PLA2G2E GO:0042742| defense response to bacterium LTF;TLR4 GO:0006355| regulation of transcription, DNA-dependent ESR1;LTF;CREB1 9306:[DB01183 DB11623] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11623|Candoxatrilat MME common genes common pathways GO:0019233| sensory perception of pain OPRK1;MME;OPRM1;OPRD1 9307:[DB01183 DB02299] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02299|Arginineamide KCNA4 common genes common pathways GO:0006811| ion transport SLCO1A2;KCNA4 GO:0055085| transmembrane transport KCNA4;SLCO1A2;ABCB1 9308:[DB01183 DB11582] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0007268| synaptic transmission GLRA1;GABRD;GABRB2;GABRA5;GABRG1;OPRK1;GABRG2;OPRD1;OPRM1 GO:0042493| response to drug GABRG3;ABCB1;CREB1;UGT1A1 GO:1901215| CREB1;GABRB2;GABRB3 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0006955| immune response TLR4;OPRK1;TNFSF11;OPRD1 GO:0071294| cellular response to zinc ion GLRA1;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;OPRM1 GO:0046330| positive regulation of JNK cascade TNFSF11;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11;TLR4;CREB1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRA1;OPRM1;OPRD1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0006811| ion transport GABRA1;GABRA4;GABRA6;GABRQ;GABRB1;GABRG2;SLCO1A2;GABRE;GABRG3;GABRB3;GLRA1;GABRP;GABRD;GABRB2;GABRA3;GABRA5;GABRG1;GABRA2 GO:0009636| response to toxin GABRB1;CES1 GO:1990830| TNFSF11;CREB1 GO:0030154| cell differentiation TNFSF11;CREB1 GO:0006810| transport GABRB3;GABRG2;GABRB1;GABRA6;GABRA4;GABRA1;ABCB1;GABRA3;GABRA5;GABRB2;GABRD GO:0007165| signal transduction GABRA5;CREB1;GABRD;GABRP;TLR4;OPRK1;OPRM1;GABRE;OPRD1;GABRB1;GABRQ;GABRA6;ESR1;GABRB3 9309:[DB01183 DB03062] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03062|(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone NMT1;NMT1 common genes common pathways 9310:[DB01183 DB08799] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08799|Antazoline HRH1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;HRH1;OPRK1 GO:0007613| memory HRH1;CREB1 GO:0007165| signal transduction ESR1;OPRD1;HRH1;OPRM1;OPRK1;TLR4;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;HRH1;OPRD1;OPRM1 GO:0006954| inflammatory response TLR4;HRH1 GO:0008542| visual learning HRH1;CREB1 9311:[DB01183 DB03934] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYCS;CYP2C8 9312:[DB01183 DB06081] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06081|Caplacizumab VWF common genes common pathways GO:0002576| platelet degranulation ALB;VWF 9313:[DB01183 DB12637] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;ADGRD1;ESR1;OPRD1;NR3C1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADGRD1;OPRK1;OPRM1;OPRD1 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;TLR4;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0006351| transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ESR1;CREB1 9314:[DB01183 DB07000] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways GO:0043066| negative regulation of apoptotic process BRAF;ALB GO:1990090| BRAF;CREB1 GO:0008542| visual learning CREB1;BRAF GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;BRAF;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BRAF;OPRD1 GO:0006468| protein phosphorylation CREB1;BRAF GO:0030154| cell differentiation CREB1;BRAF GO:0010628| positive regulation of gene expression TLR4;BRAF GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;BRAF;TLR4 9315:[DB01183 DB07070] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways GO:0030154| cell differentiation CREB1;PPARD GO:0071456| cellular response to hypoxia PPARD;OPRD1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARD GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0010033| response to organic substance PPARD;CREB1;UGT1A1 GO:0014823| response to activity CREB1;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0042060| wound healing PPARD;OPRM1 GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0043401| steroid hormone mediated signaling pathway PPARD;ESR1 GO:0006351| transcription, DNA-dependent CREB1;PPARD;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PPARD GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;ESR1 9316:[DB01183 DB05447] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05447|AVI-4557 HNF4A common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;HNF4A GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;HNF4A GO:0006355| regulation of transcription, DNA-dependent CREB1;HNF4A;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent HNF4A;CREB1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;HNF4A;TLR4;CREB1 GO:0006805| xenobiotic metabolic process HNF4A;CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;HNF4A GO:0006357| regulation of transcription from RNA polymerase II promoter HNF4A;ESR1 GO:0006351| transcription, DNA-dependent ESR1;HNF4A;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;HNF4A 9317:[DB01183 DB07485] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07485|4,4'-cyclohexane-1,1-diyldiphenol ESRRG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESRRG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESRRG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESRRG GO:0043401| steroid hormone mediated signaling pathway ESRRG;ESR1 GO:0006351| transcription, DNA-dependent ESRRG;CREB1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESRRG;ESR1 9318:[DB01183 DB05107] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;G6PD GO:0006695| cholesterol biosynthetic process G6PD;CES1 GO:0045471| response to ethanol OPRM1;G6PD;OPRK1;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;G6PD GO:0032094| response to food G6PD;OPRM1 GO:0055114| oxidation-reduction process CYP2C8;G6PD;CYP3A4 9319:[DB01183 DB01990] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01990|Cholesterol sulfate RORA common genes common pathways GO:0007623| circadian rhythm RORA;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade RORA;ESR1 GO:0006351| transcription, DNA-dependent ESR1;RORA;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;RORA GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;RORA GO:0006805| xenobiotic metabolic process RORA;CYP2C8;CES1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent RORA;CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;RORA;ESR1 GO:0042752| regulation of circadian rhythm CREB1;RORA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RORA GO:0071456| cellular response to hypoxia OPRD1;RORA GO:0048511| rhythmic process CREB1;RORA 9320:[DB01183 DB03682] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process ALB;TTR 9321:[DB01183 DB02868] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CALM1;OPRD1;OPRM1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;CALM1 GO:0002576| platelet degranulation ALB;CALM1 9322:[DB01183 DB00202] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA7;CHRNA10 GO:0007586| digestion CHRM3;UGT1A1 GO:0042493| response to drug UGT1A1;BCHE;CREB1;ABCB1 GO:0035094| response to nicotine CHRNA7;CREB1 GO:0007613| memory CREB1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;OPRM1;ESR1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CHRM3;OPRD1;OPRM1;CHRM2;CHRM1 GO:0007165| signal transduction CHRM3;TLR4;CREB1;CHRNA10;OPRK1;OPRD1;OPRM1;CHRM2;ESR1;CHRM1;CHRNA7 GO:1900273| CHRNA7;CREB1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1;CHRNA10 GO:0000187| activation of MAPK activity TLR4;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CHRNA7;OPRM1 GO:0006811| ion transport CHRNA7;SLCO1A2;CHRNA10 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CHRM2 GO:0007584| response to nutrient UGT1A1;BCHE GO:0001666| response to hypoxia CHRNA7;CREB1 9323:[DB01183 DB05243] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05243|XL019 JAK2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;JAK2 GO:0032760| positive regulation of tumor necrosis factor production JAK2;TLR4 GO:0050727| regulation of inflammatory response ESR1;JAK2;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;JAK2 GO:0042981| regulation of apoptotic process ESR1;CREB1;JAK2 GO:0045087| innate immune response JAK2;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;JAK2;UGT1A1;TLR4 GO:0008285| negative regulation of cell proliferation JAK2;OPRM1 GO:0002376| immune system process JAK2;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;JAK2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;JAK2;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;JAK2 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;JAK2 GO:0050729| positive regulation of inflammatory response JAK2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;JAK2 GO:0006468| protein phosphorylation JAK2;CREB1 GO:0030154| cell differentiation JAK2;CREB1 9324:[DB01183 DB11692] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11692|Pavinetant TACR3 common genes common pathways GO:0042220| response to cocaine OPRM1;TACR3;OPRK1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;TACR3;OPRD1;OPRM1;ESR1 GO:0007568| aging TACR3;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;TACR3;OPRK1 GO:0032355| response to estradiol stimulus TACR3;ESR1 GO:0043278| response to morphine OPRK1;TACR3;OPRM1 9325:[DB01183 DB07157] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways 9326:[DB01183 DB01404] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01404|Ginseng IL6;PTGS2;AHR common genes common pathways GO:0010628| positive regulation of gene expression TLR4;IL6 GO:0048511| rhythmic process CREB1;AHR GO:0008285| negative regulation of cell proliferation IL6;PTGS2;OPRM1 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0009636| response to toxin CES1;AHR GO:0006366| transcription from RNA polymerase II promoter AHR;CREB1;ESR1 GO:0044267| cellular protein metabolic process IL6;ALB GO:0032755| positive regulation of interleukin-6 production IL6;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;PTGS2;OPRM1;ESR1 GO:0098869| ALB;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;OPRD1;PTGS2 GO:0032722| positive regulation of chemokine production TLR4;IL6 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1;IL6 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory CREB1;PTGS2 GO:0007568| aging PTGS2;CREB1 GO:0006954| inflammatory response IL6;TLR4;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IL6 GO:0006955| immune response OPRD1;OPRK1;IL6;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;ESR1 GO:0006953| acute-phase response UGT1A1;IL6 GO:0051607| defense response to virus OPRK1;IL6 GO:0006355| regulation of transcription, DNA-dependent AHR;CREB1;ESR1 GO:0042493| response to drug PTGS2;ABCB1;UGT1A1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;IL6;AHR;CREB1 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A4 GO:0043687| post-translational protein modification ALB;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;AHR;TLR4;CREB1;ESR1 GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0050829| defense response to Gram-negative bacterium IL6;TLR4 GO:0071222| cellular response to lipopolysaccharide IL6;OPRK1;TLR4 GO:0043065| positive regulation of apoptotic process PTGS2;IL6;CREB1 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043066| negative regulation of apoptotic process ALB;IL6;PTGS2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;AHR;CYP2C8 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AHR GO:0006351| transcription, DNA-dependent ESR1;CREB1;AHR GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRM1;OPRK1 9327:[DB01183 DB08006] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;UGT1A1 GO:0055114| oxidation-reduction process DHODH;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;DHODH GO:0007595| lactation CREB1;DHODH GO:0042594| response to starvation DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process DHODH;CREB1 9328:[DB01183 DB06735] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06735|Enclomiphene CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 9329:[DB01183 DB01364] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;OPRK1;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;OPRM1;ESR1 GO:0007568| aging CREB1;ADRA1A GO:0006810| transport SLC6A2;ABCB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ADRA1A;ESR1;OPRD1;OPRM1 GO:0009636| response to toxin CES1;SLC18A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;OPRM1 GO:0055085| transmembrane transport SLC18A2;SLCO1A2;ABCB1;SLC6A2 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A;BCHE GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;OPRM1;OPRD1;ESR1 GO:0007626| locomotory behavior OPRM1;SLC18A2;OPRK1 GO:0007268| synaptic transmission OPRK1;SLC6A2;SLC18A2;OPRD1;OPRM1 GO:0042493| response to drug ADRA1A;ABCB1;CREB1;SLC6A2;UGT1A1;BCHE 9330:[DB01183 DB03769] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03769|D-Eritadenine AHCY common genes common pathways GO:0001666| response to hypoxia CREB1;AHCY GO:0007584| response to nutrient AHCY;UGT1A1 9331:[DB01183 DB04682] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 9332:[DB01183 DB07787] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07787|5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE PARP1 common genes common pathways GO:1904646| PARP1;TLR4 GO:0006366| transcription from RNA polymerase II promoter PARP1;ESR1;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PARP1;CREB1;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0071294| cellular response to zinc ion PARP1;CREB1 GO:0006351| transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ESR1;CREB1 9333:[DB01183 DB02426] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02426|Carboxyatractyloside SLC25A4 common genes common pathways GO:0016032| viral reproduction CREB1;SLC25A4 GO:0006810| transport ABCB1;SLC25A4 GO:0055085| transmembrane transport ABCB1;SLC25A4;SLCO1A2 9334:[DB01183 DB06997] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways GO:0006468| protein phosphorylation CREB1;MET GO:0007165| signal transduction CREB1;TLR4;OPRK1;MET;OPRM1;OPRD1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;MET 9335:[DB01183 DB05464] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways GO:0006366| transcription from RNA polymerase II promoter ESR1;NFKB1;CREB1;NFKB2 GO:0048511| rhythmic process NFKB2;CREB1 GO:0007568| aging CREB1;NFKB2 GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB2;TLR4;NFKB1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;NFKB1;CREB1;TLR4;NFKB2;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;NFKB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NFKB1;CREB1;NFKB2 GO:0010629| negative regulation of gene expression NFKB1;OPRD1;ESR1;CREB1 GO:0006954| inflammatory response NFKB1;NFKB2;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;TLR4;NFKB2 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;NFKB2;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NFKB1 GO:0006351| transcription, DNA-dependent NFKB1;ESR1;NFKB2;CREB1 GO:0043066| negative regulation of apoptotic process ALB;NFKB1 GO:0071222| cellular response to lipopolysaccharide NFKB1;OPRK1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;ESR1;CREB1;NFKB2;TLR4 GO:0071260| cellular response to mechanical stimulus NFKB1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB2;NFKB1;ESR1 GO:0045087| innate immune response NFKB1;NFKB2;TLR4 9336:[DB01183 DB04381] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0008152| metabolic process ALDH2;CES1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;ALDH2;CYP3A4 9337:[DB01183 DB01644] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GSR;CYP2C8 GO:0098869| GSR;ALB 9338:[DB01183 DB03991] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;NEU2 GO:0006629| lipid metabolic process NEU2;CYP3A4 9339:[DB01183 DB08350] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ABL1;ESR1 GO:0045087| innate immune response ABL1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;ABL1 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TLR4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0002322| B cell proliferation involved in immune response ABL1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ABL1;OPRM1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;ABL1 GO:0006468| protein phosphorylation CREB1;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;ABL1 9340:[DB01183 DB08743] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 9341:[DB01183 DB05200] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05200|AT2220 GAA common genes common pathways GO:0008152| metabolic process GAA;CES1;UGT1A1 GO:0007626| locomotory behavior OPRM1;GAA;OPRK1 9342:[DB01183 DB01472] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01472|4-Methoxyamphetamine SLC6A3;SLC6A4;SLC18A2;ADRA1A;ADRA2A;MAOA;MAOB;CYP2D6 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADRA1A;OPRK1;ADRA2A GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0007613| memory CREB1;SLC6A4 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;OPRM1;ESR1 GO:0007568| aging SLC6A3;ADRA1A;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;ADRA2A;OPRK1;ADRA1A GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0009636| response to toxin MAOB;SLC6A4;SLC18A2;CES1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A4;SLCO1A2;SLC18A2 GO:0042220| response to cocaine OPRK1;SLC6A3;OPRM1 GO:0001666| response to hypoxia CREB1;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;MAOB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0045471| response to ethanol OPRM1;SLC6A3;OPRK1;MAOB;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;OPRD1;OPRM1;ESR1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0007626| locomotory behavior SLC6A3;OPRK1;OPRM1;SLC18A2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0042493| response to drug ADRA1A;ABCB1;SLC6A3;UGT1A1;MAOB;CREB1;SLC6A4 GO:0007268| synaptic transmission SLC18A2;OPRM1;OPRD1;OPRK1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;MAOB;CYP3A4;MAOA GO:0007595| lactation SLC6A3;CREB1 GO:0035094| response to nicotine CREB1;SLC6A3 9343:[DB01183 DB14707] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14707|Cemiplimab PDCD1 common genes common pathways GO:0043065| positive regulation of apoptotic process CREB1;PDCD1 GO:0043066| negative regulation of apoptotic process ALB;PDCD1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;PDCD1;OPRM1;OPRD1;ESR1 GO:0002376| immune system process PDCD1;TLR4 9344:[DB01183 DB12960] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12960|INCB-9471 CCR5 common genes common pathways GO:0006954| inflammatory response TLR4;CCR5 GO:0006955| immune response TLR4;CCR5;OPRK1;OPRD1 GO:0016032| viral reproduction CREB1;CCR5 GO:0071222| cellular response to lipopolysaccharide TLR4;CCR5;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;CCR5 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CCR5;OPRM1;OPRD1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1;CCR5 9345:[DB01183 DB09333] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09333|Iopodic acid DIO3;ALB common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0040018| positive regulation of multicellular organism growth CREB1;DIO3 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0055114| oxidation-reduction process DIO3;CYP2C8;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 9346:[DB01183 DB06707] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0007165| signal transduction OPRM1;OPRD1;ESR1;ADRA2C;ADRA2B;CREB1;TLR4;ADRA2A;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADRA2B;ADRA2C;OPRK1;ADRA2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1;ADRA2C GO:0000187| activation of MAPK activity TLR4;ADRA2B 9347:[DB01183 DB00293] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0009636| response to toxin TYMS;CES1 GO:0031100| organ regeneration UGT1A1;FPGS GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0007568| aging CREB1;TYMS GO:0042493| response to drug ABCB1;CREB1;TYMS;UGT1A1 GO:0007623| circadian rhythm TYMS;CREB1 GO:0001889| liver development FPGS;UGT1A1 GO:0045471| response to ethanol OPRM1;UGT1A1;TYMS;OPRK1 9348:[DB01183 DB07602] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways GO:0001889| liver development UGT1A1;EGFR GO:0042060| wound healing OPRM1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;EGFR GO:0007623| circadian rhythm EGFR;CREB1 GO:0071260| cellular response to mechanical stimulus TLR4;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;EGFR;ESR1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0006468| protein phosphorylation EGFR;CREB1 GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0071363| cellular response to growth factor stimulus EGFR;CREB1;OPRD1 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0007165| signal transduction OPRD1;OPRM1;ESR1;EGFR;OPRK1;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;EGFR;ESR1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade EGFR;TLR4;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 9349:[DB01183 DB08818] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08818|Hyaluronic acid CD44;ICAM1;HMMR;NCAN;VCAN;C1QBP;HAPLN1;HAPLN3;HAPLN4;HABP2;LAYN;STAB2;TNFAIP6;IMPG2;HABP4 common genes common pathways GO:0006955| immune response OPRD1;OPRK1;C1QBP;TLR4 GO:0016032| viral reproduction CREB1;C1QBP;ICAM1 GO:0051092| positive regulation of NF-kappaB transcription factor activity ICAM1;TLR4 GO:0006954| inflammatory response TNFAIP6;TLR4 GO:0043687| post-translational protein modification VCAN;ALB GO:0055114| oxidation-reduction process STAB2;CYP3A4;CYP2C8 GO:0042742| defense response to bacterium TLR4;STAB2 GO:0042493| response to drug ABCB1;ICAM1;UGT1A1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;HABP4;CREB1;C1QBP GO:0071260| cellular response to mechanical stimulus HABP4;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;C1QBP GO:0045087| innate immune response TLR4;C1QBP GO:0043066| negative regulation of apoptotic process ALB;CD44 GO:0002576| platelet degranulation HABP4;ALB GO:0043065| positive regulation of apoptotic process C1QBP;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;ICAM1;OPRK1 GO:0006351| transcription, DNA-dependent ESR1;C1QBP;CREB1;HABP4 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1;ICAM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;ICAM1;UGT1A1 GO:0001666| response to hypoxia ICAM1;CREB1 GO:1990830| CREB1;ICAM1 GO:0044267| cellular protein metabolic process ALB;VCAN GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ICAM1 GO:0032868| response to insulin stimulus OPRK1;ICAM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CD44;OPRM1;TLR4;ICAM1 GO:0014070| response to organic cyclic compound UGT1A1;ICAM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation CD44;OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;TNFAIP6;OPRK1 GO:0045429| positive regulation of nitric oxide biosynthetic process ICAM1;TLR4;OPRM1;ESR1 GO:0032689| negative regulation of interferon-gamma production C1QBP;TLR4 GO:0006898| receptor-mediated endocytosis STAB2;ALB GO:0002376| immune system process C1QBP;TLR4 GO:0071456| cellular response to hypoxia ICAM1;OPRD1 9350:[DB01183 DB07609] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2C8;UGT1A1 9351:[DB01183 DB03323] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03323|Maltose AMY2B;aglA common genes common pathways GO:0008152| metabolic process UGT1A1;AMY2B;CES1 GO:0007586| digestion UGT1A1;AMY2B 9352:[DB01183 DB04617] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways 9353:[DB01183 DB00576] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00576|Sulfamethizole CYP2C9;ALB common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043069| negative regulation of programmed cell death ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;CYP2C9 GO:0051659| maintenance of mitochondrion location ALB GO:0017144| drug metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB 9354:[DB01183 DB04463] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04463|3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol CBR1;CBR1 common genes common pathways GO:0055114| oxidation-reduction process CBR1;CYP3A4;CYP2C8 GO:0030855| epithelial cell differentiation CBR1;CES1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CBR1 9355:[DB01183 DB08238] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;FGF1;TLR4;CREB1 GO:0007165| signal transduction FGF1;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0030154| cell differentiation FGF1;CREB1 GO:0000187| activation of MAPK activity FGF1;TLR4 9356:[DB01183 DB00151] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CBS;CYP3A4;CDO1 GO:0042493| response to drug MGMT;ABCB1;UGT1A1;CREB1;GCLM GO:0007595| lactation CREB1;CDO1 GO:0006954| inflammatory response TLR4;CDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CTH;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;TLR4 GO:0045471| response to ethanol CDO1;OPRM1;MGMT;UGT1A1;OPRK1 GO:0033762| response to glucagon stimulus CREB1;CDO1 GO:0071260| cellular response to mechanical stimulus TLR4;GCLC GO:0043066| negative regulation of apoptotic process ALB;GCLC;MGMT;CTH GO:0008152| metabolic process CES1;UGT1A1;CBS GO:0055085| transmembrane transport SLCO1A2;SLC16A10;ABCB1 GO:0014070| response to organic cyclic compound MGMT;UGT1A1 GO:0009636| response to toxin MGMT;CES1 GO:0007584| response to nutrient GCLC;GCLM;UGT1A1 GO:0014823| response to activity GCLC;GCLM;CREB1 GO:1990830| CTH;GCLM;CREB1 GO:0007568| aging GCLM;CREB1;GSS;GCLC GO:0051384| response to glucocorticoid stimulus GOT1;CDO1;UGT1A1 GO:0035729| cellular response to hepatocyte growth factor stimulus GCLC;GCLM;CREB1 9357:[DB01183 DB02751] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02751|Glycocyamine GAMT common genes common pathways 9358:[DB01183 DB03185] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 9359:[DB01183 DB03453] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways GO:0030890| positive regulation of B cell proliferation IL2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration IL2;ESR1;OPRM1 GO:0050729| positive regulation of inflammatory response IL2;TLR4 GO:0007186| G-protein coupled receptor signaling pathway IL2;OPRK1;OPRM1;OPRD1 GO:0002376| immune system process IL2;TLR4 GO:0006955| immune response IL2;OPRK1;TLR4;OPRD1 GO:0045471| response to ethanol OPRK1;IL2;UGT1A1;OPRM1 GO:0032729| positive regulation of interferon-gamma production TLR4;IL2 GO:0043066| negative regulation of apoptotic process ALB;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;IL2 9360:[DB01183 DB08024] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9361:[DB01183 DB07586] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;HDAC8;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;HDAC8 GO:0006355| regulation of transcription, DNA-dependent ESR1;HDAC8;CREB1 GO:0010629| negative regulation of gene expression HDAC8;OPRD1;ESR1;CREB1 9362:[DB01183 DB00074] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FCGR1A;FCGR2B GO:0002376| immune system process C1QA;C1S;C1QC;IL2RA;FCGR2A;FCGR1A;TLR4;C1R;C1QB GO:0007165| signal transduction IL2RB;TLR4;CREB1;FCGR2B;FCGR1A;OPRK1;OPRD1;FCGR2C;OPRM1;ESR1 GO:1904646| FCGR2B;TLR4 GO:0046330| positive regulation of JNK cascade TLR4;FCGR2B GO:0043066| negative regulation of apoptotic process ALB;IL2RB GO:0045087| innate immune response FCGR1A;C1R;C1QB;TLR4;C1QA;C1QC;C1S GO:0009617| response to bacterium TLR4;FCGR2B GO:0006954| inflammatory response IL2RA;TLR4;FCGR2B GO:0016032| viral reproduction IL2RB;CREB1;FCGR2B GO:0006955| immune response IL2RA;FCGR3A;FCGR2C;OPRD1;C1QC;C1R;FCGR3B;FCGR2B;TLR4;FCGR1A;OPRK1 9363:[DB01183 DB03516] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0017144| drug metabolic process AOX1;UGT1A1;CYP2C8;CYP3A4 GO:1900745| XDH;OPRK1 GO:0010629| negative regulation of gene expression ESR1;XDH;OPRD1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;AOX1;DPYD;XDH;CYP3A4 GO:0007595| lactation CREB1;XDH 9364:[DB01183 DB07330] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07330|trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium PARP1 common genes common pathways GO:0071294| cellular response to zinc ion PARP1;CREB1 GO:0006351| transcription, DNA-dependent CREB1;PARP1;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PARP1;TLR4;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PARP1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP1;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;PARP1 GO:1904646| TLR4;PARP1 9365:[DB01183 DB03128] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0007613| memory CHRNA7;CREB1 GO:0007186| G-protein coupled receptor signaling pathway CHRM2;CHRM1;OPRD1;OPRM1;OPRK1;CHRM4;CHRM3 GO:0015711| organic anion transport SLC22A5;SLCO1A2;SLC22A1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRM1;CHRM2;CHRNA7;CHRM3;CREB1;TLR4;CHRM4;OPRK1 GO:1900273| CHRNA7;CREB1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:0000187| activation of MAPK activity TLR4;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CHRNA7;TLR4 GO:0055085| transmembrane transport SLC22A5;SLCO1A2;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A5 GO:0006811| ion transport SLC22A1;CHRNA7;SLCO1A2;SLC22A5 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CHRM2 GO:0001666| response to hypoxia CREB1;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;OPRM1 GO:0007586| digestion CHRM3;UGT1A1 GO:0035094| response to nicotine CHRNA7;CREB1 9366:[DB01183 DB08888] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08888|Ocriplasmin FN1;A2M;SERPINF2 common genes common pathways GO:0002576| platelet degranulation FN1;ALB;SERPINF2;A2M GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINF2;ESR1;CREB1;TLR4 GO:0042060| wound healing OPRM1;FN1 GO:0046330| positive regulation of JNK cascade TLR4;SERPINF2 GO:0048863| stem cell differentiation ESR1;A2M GO:0006953| acute-phase response UGT1A1;FN1;SERPINF2 GO:0043687| post-translational protein modification ALB;FN1 GO:0010628| positive regulation of gene expression FN1;TLR4 GO:0048146| positive regulation of fibroblast proliferation FN1;ESR1 GO:0010033| response to organic substance CREB1;UGT1A1;SERPINF2 GO:0044267| cellular protein metabolic process ALB;FN1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;SERPINF2;OPRM1 9367:[DB01183 DB03824] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03824|7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline PNMT common genes common pathways 9368:[DB01183 DB01306] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01306|Insulin Aspart INSR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;INSR;ESR1 GO:0006355| regulation of transcription, DNA-dependent INSR;CREB1;ESR1 GO:0000187| activation of MAPK activity TLR4;INSR GO:0008584| male gonad development INSR;ESR1 GO:0007613| memory INSR;CREB1 GO:0006468| protein phosphorylation CREB1;INSR GO:0007186| G-protein coupled receptor signaling pathway OPRK1;INSR;OPRD1;OPRM1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;INSR;ESR1;OPRM1 9369:[DB01183 DB02198] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways GO:0098869| ALB;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006954| inflammatory response TLR4;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C8 9370:[DB01183 DB00148] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0006811| ion transport SLC6A8;SLCO1A2;SLC22A5 GO:0055085| transmembrane transport SLC22A5;SLCO1A2;SLC6A8;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006810| transport ABCB1;SLC6A8 GO:0015711| organic anion transport SLCO1A2;SLC22A5 9371:[DB01183 DB07780] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042981| regulation of apoptotic process RABGGTA;CREB1;RABGGTB;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;KRAS GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CES1 GO:0001889| liver development UGT1A1;KRAS GO:0016032| viral reproduction CREB1;FDPS GO:0051092| positive regulation of NF-kappaB transcription factor activity KRAS;TLR4 GO:0008542| visual learning CREB1;KRAS GO:0043687| post-translational protein modification RABGGTB;RABGGTA;ALB GO:0007165| signal transduction KRAS;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;FDPS;CYP3A4 GO:0051384| response to glucocorticoid stimulus KRAS;UGT1A1 GO:0010628| positive regulation of gene expression KRAS;TLR4 GO:0007411| axon guidance CREB1;KRAS GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FNTA 9372:[DB01183 DB06090] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06090|Bradanicline CHRNA7 common genes common pathways GO:0035094| response to nicotine CHRNA7;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;OPRM1 GO:0000187| activation of MAPK activity TLR4;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CHRNA7;OPRM1 GO:0006811| ion transport SLCO1A2;CHRNA7 GO:0001666| response to hypoxia CREB1;CHRNA7 GO:0007613| memory CREB1;CHRNA7 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;CHRNA7;TLR4;CREB1;OPRK1 GO:1900273| CHRNA7;CREB1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 9373:[DB01183 DB01614] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes ALB common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;ESR1;HTR2A;OPRM1;OPRD1;OPRK1;ADRA1A GO:0045471| response to ethanol OPRM1;UGT1A1;DRD2;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0019233| sensory perception of pain OPRK1;HTR2A;OPRM1;OPRD1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0007626| locomotory behavior OPRK1;DRD2;DRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;DRD2 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD1 GO:0048148| behavioral response to cocaine OPRK1;DRD2;HTR2A;DRD1 GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0007268| synaptic transmission OPRK1;HTR2A;OPRM1;OPRD1 GO:0042493| response to drug ABCB1;DRD2;ADRA1A;CREB1;UGT1A1;DRD1;HTR2A GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0043278| response to morphine DRD2;OPRK1;OPRM1 GO:0008542| visual learning DRD1;CREB1;DRD2 GO:0035094| response to nicotine DRD2;CREB1 GO:0042711| maternal behavior DRD1;OPRK1 GO:0016032| viral reproduction HTR2A;CREB1 GO:0007613| memory HTR2A;DRD1;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;ESR1;HTR2A;OPRM1;ADRA1A GO:0007568| aging HTR2A;ADRA1A;CREB1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0043069| negative regulation of programmed cell death ALB GO:0014002| astrocyte development TLR4;DRD1 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;ADRA1A;HTR1A;HTR2A;OPRM1;OPRD1;ADRA1B;DRD1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0007610| behavior OPRK1;HTR1A;HTR2A GO:0007165| signal transduction CREB1;TLR4;OPRK1;ADRA1A;DRD2;ESR1;HTR1A;HTR2A;OPRM1;OPRD1;ADRA1B;DRD1 GO:0006898| receptor-mediated endocytosis ALB GO:1900273| CREB1;DRD2 GO:0098869| ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;ADRA1A;DRD2;TLR4 GO:0001895| retina homeostasis ALB GO:0042220| response to cocaine DRD2;OPRK1;DRD1;OPRM1 GO:0044267| cellular protein metabolic process ALB GO:0007409| axonogenesis DRD2;CREB1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0009636| response to toxin DRD2;CES1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRM1;OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A;DRD2 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0010628| positive regulation of gene expression DRD1;TLR4 9374:[DB01183 DB13151] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0043687| post-translational protein modification F5;FGA;ALB GO:0055114| oxidation-reduction process F8;CYP2C8;CYP3A4 GO:0006953| acute-phase response F2;UGT1A1;F8 GO:0007623| circadian rhythm CREB1;F7 GO:0002576| platelet degranulation F5;FGA;F13A1;ALB;F8;FGB GO:0045087| innate immune response FGB;TLR4;FGA GO:0014070| response to organic cyclic compound UGT1A1;F7 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGB;OPRM1;FGA;TLR4 GO:0044267| cellular protein metabolic process FGA;F2;F5;ALB GO:0001666| response to hypoxia CREB1;F7 GO:0043627| response to estrogen stimulus ESR1;F7;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway F2;OPRK1;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus F7;ESR1 GO:0002224| toll-like receptor signaling pathway FGB;TLR4;FGA GO:0002376| immune system process FGB;FGA;TLR4 GO:0031100| organ regeneration UGT1A1;F7 GO:0007165| signal transduction FGB;OPRD1;OPRM1;ESR1;FGA;OPRK1;TLR4;CREB1 9375:[DB01183 DB11914] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11914|Lebrikizumab IL13;IL13 common genes common pathways GO:0006955| immune response TLR4;OPRK1;IL13;OPRD1 GO:0006954| inflammatory response IL13;TLR4 GO:0035094| response to nicotine CREB1;IL13 GO:1901215| IL13;CREB1 GO:0071260| cellular response to mechanical stimulus IL13;TLR4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;IL13;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;IL13;OPRK1 GO:0030890| positive regulation of B cell proliferation TLR4;IL13 GO:0043032| positive regulation of macrophage activation TLR4;IL13 9376:[DB01183 DB01382] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0007613| memory ABCC8;CREB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ABCC8;ESR1;OPRD1;OPRM1 GO:0055085| transmembrane transport ABCC8;SLCO1A2;ABCB1 GO:0032868| response to insulin stimulus OPRK1;ABCC8 GO:0006811| ion transport KCNJ1;SLCO1A2 GO:0032496| response to lipopolysaccharide ABCC8;OPRM1;TLR4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;ABCC8 GO:0032760| positive regulation of tumor necrosis factor production TLR4;ABCC8 GO:0008542| visual learning ABCC8;CREB1 9377:[DB01183 DB07448] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07448|(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid LAP3 common genes common pathways 9378:[DB01183 DB08836] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes SLCO1A2 common pathways GO:0007586| digestion SLC15A1;UGT1A1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLC15A1 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO1A2 GO:0015711| organic anion transport SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0006810| transport SLC15A1;ABCB1 9379:[DB01183 DB00714] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0048511| rhythmic process DRD4;CREB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR1B;OPRD1;HTR1D;OPRM1;DRD1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0001666| response to hypoxia DRD2;CREB1 GO:0010628| positive regulation of gene expression TLR4;DRD1 GO:0045600| positive regulation of fat cell differentiation HTR2C;CREB1;HTR2A GO:0008344| adult locomotory behavior DRD4;OPRD1 GO:0042220| response to cocaine OPRM1;DRD1;DRD5;DRD3;OPRK1;DRD2;HTR1B GO:0000187| activation of MAPK activity TLR4;ADRA2B;DRD4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;TLR4;DRD2;HTR2B;HTR2C GO:0009636| response to toxin DRD2;CES1;HTR1D GO:0051930| regulation of sensory perception of pain OPRK1;ADRA2C;OPRD1;OPRM1 GO:0007409| axonogenesis DRD2;CREB1 GO:0007610| behavior HTR2A;HTR1A;OPRK1;HTR2C;HTR2B;HTR1B GO:0007165| signal transduction DRD1;DRD5;ADRA2B;HTR2A;ESR1;ADRA2C;DRD4;HTR1A;HTR1D;OPRD1;OPRM1;OPRK1;ADRA2A;HTR2B;HTR2C;DRD2;HTR1B;DRD3;TLR4;CREB1 GO:1900273| CREB1;DRD2 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007568| aging CREB1;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;HTR1D;OPRM1;OPRK1;ADRA2A;HTR1B GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A GO:0007613| memory DRD1;HTR2A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway DRD3;HTR1B;DRD2;OPRK1;HTR2C;HTR2B;ADRA2A;OPRD1;HTR1D;OPRM1;HTR2A;ADRA2B;HTR1A;DRD4;ADRA2C;DRD5;DRD1 GO:0014002| astrocyte development TLR4;DRD1 GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning DRD1;DRD2;DRD3;CREB1 GO:0043278| response to morphine OPRM1;DRD3;DRD2;OPRK1 GO:0042752| regulation of circadian rhythm DRD4;CREB1 GO:0016032| viral reproduction CREB1;HTR2A GO:0042711| maternal behavior OPRK1;DRD1 GO:0048149| behavioral response to ethanol DRD4;OPRM1;DRD2 GO:0042493| response to drug DRD1;HTR2A;HTR2B;HTR2C;ABCB1;HTR1B;DRD2;DRD3;CREB1;UGT1A1 GO:0007268| synaptic transmission HTR2A;OPRM1;HTR1D;OPRD1;DRD5;HTR2C;OPRK1;HTR1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;ESR1 GO:0048148| behavioral response to cocaine HTR2A;DRD4;DRD1;DRD3;DRD2;OPRK1 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;DRD5;OPRM1;DRD3 GO:0007626| locomotory behavior DRD3;DRD2;OPRK1;HTR2C;OPRM1;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;DRD2;TLR4;DRD3;CREB1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HTR2B GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TLR4 GO:0045471| response to ethanol HTR1B;DRD2;OPRK1;UGT1A1;DRD3;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1;OPRK1;HTR2B;HTR2C GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0042060| wound healing OPRM1;DRD5 9380:[DB01183 DB09099] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes ABCB1;CYP3A4 common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger SSTR4;SSTR1;SSTR2;SSTR5;SSTR3;OPRM1;OPRD1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007584| response to nutrient UGT1A1;SSTR2;SSTR1 GO:0008285| negative regulation of cell proliferation OPRM1;SSTR3;SSTR5;SSTR2;SSTR1;SSTR4 GO:1990830| SSTR1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0036378| CYP3A4 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0002933| CYP3A4;CYP2C8 GO:0007165| signal transduction SSTR4;OPRK1;SSTR2;CREB1;SSTR1;TLR4;SSTR5;OPRM1;OPRD1;ESR1;SSTR3 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0071392| cellular response to estradiol stimulus SSTR2;UGT1A1;SSTR1;SSTR3;ESR1 GO:0042908| xenobiotic transport ABCB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;SSTR2;OPRM1;OPRD1 GO:0006810| transport ABCB1 GO:0007186| G-protein coupled receptor signaling pathway SSTR5;SSTR3;OPRM1;OPRD1;OPRK1;SSTR4;SSTR1;SSTR2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0071385| cellular response to glucocorticoid stimulus SSTR3;SSTR5;UGT1A1;SSTR2;SSTR4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission SSTR4;OPRK1;OPRM1;OPRD1;SSTR3;SSTR5 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042594| response to starvation SSTR3;SSTR1;UGT1A1;SSTR2 GO:0006629| lipid metabolic process CYP3A4 GO:0007586| digestion UGT1A1;SSTR2;SSTR1 GO:0006706| steroid catabolic process CYP3A4 GO:0007218| neuropeptide signaling pathway SSTR2;SSTR1;OPRK1;OPRM1;OPRD1;SSTR3 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP3A4 9381:[DB01183 DB03223] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03223|Diphthamide EEF2 common genes common pathways GO:0007568| aging CREB1;EEF2 GO:0032355| response to estradiol stimulus EEF2;ESR1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;EEF2 GO:0045471| response to ethanol OPRK1;UGT1A1;EEF2;OPRM1 9382:[DB01183 DB06843] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;GNAS;ABCB1 GO:0007626| locomotory behavior OPRK1;OPRM1;ADCY5 GO:0045672| positive regulation of osteoclast differentiation CREB1;GNAS GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;ADCY5;GNAS GO:0007165| signal transduction CREB1;TLR4;ADCY2;GNAS;OPRK1;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GNAS;ADCY2;OPRD1;OPRM1;ADCY5 GO:0007204| elevation of cytosolic calcium ion concentration ADCY5;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADCY5;OPRK1;ADCY2 9383:[DB01183 DB08675] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PTGIS GO:0045019| negative regulation of nitric oxide biosynthetic process PTGIS;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;PTGIS GO:0006629| lipid metabolic process PTGIS;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;PTGIS;CYP3A4 9384:[DB01183 DB00926] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00926|Etretinate RARA;RXRA;RARB;RXRG;RXRB;RARG;CYP19A1;CYP26A1;CRABP1 common genes common pathways GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;RARA;RARG;RXRB;RXRA;RARB;RXRG GO:0016032| viral reproduction RXRA;CREB1 GO:0071391| cellular response to estrogen stimulus ESR1;RARA GO:0055114| oxidation-reduction process CYP19A1;CYP2C8;CYP26A1;CYP3A4 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;RXRA;ESR1;RARA GO:0008361| regulation of cell size CREB1;RARG GO:0006355| regulation of transcription, DNA-dependent RARB;RXRG;RXRB;RXRA;CREB1;RARA;RARG;ESR1 GO:0010629| negative regulation of gene expression RARA;OPRD1;ESR1;CREB1 GO:0042981| regulation of apoptotic process ESR1;RARA;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARA;RARG;ESR1;RARB;RXRA GO:0043066| negative regulation of apoptotic process RARG;RARA;ALB;RARB GO:0060065| uterus development ESR1;CYP19A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP26A1;CYP3A4;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;RARG;ESR1;RARB;RXRG;CREB1;RXRB;TLR4;RXRA GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;RARA GO:0043065| positive regulation of apoptotic process RARG;RARB;CREB1 GO:0006351| transcription, DNA-dependent RARA;RARG;ESR1;RARB;RXRG;RXRB;RXRA;CREB1 GO:0001889| liver development UGT1A1;RARA GO:0043401| steroid hormone mediated signaling pathway ESR1;RARA;RARG;RXRA;RXRB;RARB;RXRG GO:0045471| response to ethanol RARA;OPRM1;OPRK1;UGT1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA GO:0042573| retinoic acid metabolic process CYP26A1;UGT1A1 GO:0008285| negative regulation of cell proliferation RARB;OPRM1;RARA;RARG GO:0010628| positive regulation of gene expression RARA;RARG;TLR4 GO:1990830| RARG;CREB1 GO:0015721| bile acid and bile salt transport SLCO1A2;RXRA;ALB GO:0008584| male gonad development ESR1;RARA GO:0030879| mammary gland development CYP19A1;CREB1 GO:0007165| signal transduction RARB;OPRK1;CREB1;TLR4;RARA;OPRM1;OPRD1;ESR1;CRABP1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;RARA GO:0032689| negative regulation of interferon-gamma production RARA;TLR4 GO:0006468| protein phosphorylation CREB1;RARA GO:0032355| response to estradiol stimulus RARA;ESR1 9385:[DB01183 DB11611] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11611|Lifitegrast ITGAL;CYP2C9;SLCO1A2;SLCO2B1 common genes SLCO1A2 common pathways GO:0006954| inflammatory response TLR4;ITGAL GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLCO2B1 GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLCO1A2 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;ITGAL;CREB1;TLR4;OPRK1 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0015711| organic anion transport SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB;SLCO2B1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 9386:[DB01183 DB00039] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00039|Palifermin FGFR2;NRP1;FGFR1;FGFR4;FGFR3;HSPG2 common genes common pathways GO:0007409| axonogenesis FGFR2;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGFR2;NRP1;OPRM1;FGFR4;TLR4;FGFR3 GO:0044267| cellular protein metabolic process ALB;HSPG2 GO:0030855| epithelial cell differentiation CES1;FGFR2 GO:0060523| prostate epithelial cord elongation ESR1;FGFR2 GO:0010628| positive regulation of gene expression TLR4;FGFR4 GO:0007411| axon guidance NRP1;CREB1 GO:0006468| protein phosphorylation FGFR1;FGFR2;CREB1;FGFR3;FGFR4 GO:0030154| cell differentiation CREB1;NRP1;HSPG2 GO:0006898| receptor-mediated endocytosis ALB;HSPG2 GO:0035729| cellular response to hepatocyte growth factor stimulus NRP1;CREB1 GO:0010863| positive regulation of phospholipase C activity ESR1;FGFR1 GO:0007165| signal transduction OPRD1;OPRM1;NRP1;ESR1;OPRK1;TLR4;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;FGFR1;ESR1 GO:0010629| negative regulation of gene expression FGFR1;ESR1;OPRD1;CREB1 GO:0006954| inflammatory response TLR4;HSPG2 GO:0060687| regulation of branching involved in prostate gland morphogenesis FGFR2;ESR1 GO:0032496| response to lipopolysaccharide FGFR2;OPRM1;UGT1A1;TLR4 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1;FGFR2 GO:0042060| wound healing OPRM1;FGFR2 GO:0045471| response to ethanol OPRM1;FGFR2;UGT1A1;OPRK1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;FGFR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;FGFR2;CREB1;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus FGFR2;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR2;FGFR1;ESR1 GO:0006629| lipid metabolic process HSPG2;CYP3A4 9387:[DB01183 DB06699] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06699|Degarelix GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GNRHR;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction CREB1;TLR4;GNRHR;OPRK1;ESR1;OPRM1;OPRD1 9388:[DB01183 DB05687] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:1900273| DRD2;CREB1 GO:0007610| behavior OPRK1;HTR2A GO:0007165| signal transduction HTR2A;ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRM1;OPRD1;OPRK1;DRD2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1 GO:0007613| memory CREB1;HTR2A GO:0007568| aging HTR2A;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0001666| response to hypoxia DRD2;CREB1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0007409| axonogenesis CREB1;DRD2 GO:0009636| response to toxin CES1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1;HTR2A GO:0042220| response to cocaine OPRK1;DRD2;OPRM1 GO:0007626| locomotory behavior DRD2;OPRK1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD2 GO:0048148| behavioral response to cocaine HTR2A;OPRK1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol OPRM1;UGT1A1;DRD2;OPRK1 GO:0019233| sensory perception of pain HTR2A;OPRD1;OPRM1;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0016032| viral reproduction CREB1;HTR2A GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning CREB1;DRD2 GO:0043278| response to morphine DRD2;OPRK1;OPRM1 GO:0007268| synaptic transmission HTR2A;OPRM1;OPRD1;OPRK1 GO:0042493| response to drug HTR2A;DRD2;ABCB1;CREB1;UGT1A1 GO:0048149| behavioral response to ethanol DRD2;OPRM1 9389:[DB01183 DB01400] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01400|Neostigmine ACHE;BCHE common genes common pathways GO:0042493| response to drug CREB1;BCHE;UGT1A1;ABCB1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 9390:[DB01183 DB04972] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04972|Canfosfamide GSTP1 common genes common pathways GO:0098869| ALB;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin CES1;GSTP1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;CYP3A4;CES1 GO:0008152| metabolic process CES1;GSTP1;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0071222| cellular response to lipopolysaccharide GSTP1;OPRK1;TLR4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;GSTP1 GO:0045471| response to ethanol OPRM1;OPRK1;GSTP1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 9391:[DB01183 DB06822] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0043687| post-translational protein modification SERPINC1;ALB GO:0007595| lactation CREB1;SERPINC1 GO:0051924| regulation of calcium ion transport OPRD1;CXCL12 GO:0006955| immune response TLR4;OPRK1;CXCL12;OPRD1 GO:0033603| positive regulation of dopamine secretion OPRK1;CXCL12 GO:0009314| response to radiation OPRK1;OPRM1;CXCL12 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0044267| cellular protein metabolic process ALB;SERPINC1 GO:0008344| adult locomotory behavior CXCL12;OPRD1 GO:0007411| axon guidance CXCL12;CREB1 GO:0007584| response to nutrient SERPINC1;UGT1A1 GO:0001666| response to hypoxia CXCL12;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;CXCL12 GO:0007165| signal transduction OPRM1;CXCL12;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0031100| organ regeneration CXCL12;UGT1A1 9392:[DB01183 DB05578] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05578|Ramucirumab KDR common genes common pathways GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0006468| protein phosphorylation KDR;CREB1 GO:0030154| cell differentiation KDR;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;KDR;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;KDR GO:0010629| negative regulation of gene expression OPRD1;ESR1;KDR;CREB1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0016032| viral reproduction CREB1;KDR 9393:[DB01183 DB03974] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03974|L-Homoarginine NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 9394:[DB01183 DB09564] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09564|Insulin Degludec INSR common genes common pathways GO:0008584| male gonad development INSR;ESR1 GO:0000187| activation of MAPK activity INSR;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;INSR GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;INSR GO:0007186| G-protein coupled receptor signaling pathway OPRK1;INSR;OPRM1;OPRD1 GO:0007613| memory CREB1;INSR GO:0006468| protein phosphorylation CREB1;INSR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0006355| regulation of transcription, DNA-dependent INSR;CREB1;ESR1 9395:[DB01183 DB14517] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes ALB common pathways GO:0008542| visual learning APP;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;APP GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:1901215| APP;CREB1 GO:0043687| post-translational protein modification TF;APP;ALB GO:0007268| synaptic transmission OPRM1;OPRD1;APP;OPRK1 GO:0042493| response to drug ATP1A1;ABCB1;UGT1A1;CREB1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;APP;CREB1 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:1990090| CREB1;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;APP GO:0045087| innate immune response APP;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;APP GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation TF;APP;ALB GO:0043065| positive regulation of apoptotic process CREB1;APP GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;APP GO:0007626| locomotory behavior APP;OPRK1;OPRM1 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0046330| positive regulation of JNK cascade APP;TLR4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:1903223| TLR4;APP GO:0008285| negative regulation of cell proliferation OPRM1;APP GO:0010628| positive regulation of gene expression APP;TLR4 GO:1904646| APP;TLR4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0000187| activation of MAPK activity APP;TLR4 GO:0001895| retina homeostasis TF;ALB GO:0008344| adult locomotory behavior APP;OPRD1 GO:0044267| cellular protein metabolic process ALB;APP;TF GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;TLR4;OPRM1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport ATP1A1;SLCO1A2;TF GO:0007409| axonogenesis CREB1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1 GO:0098869| ALB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;APP GO:1900273| APP;CREB1 GO:0006898| receptor-mediated endocytosis ALB GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;APP;OPRK1 GO:0043069| negative regulation of programmed cell death ALB GO:0006468| protein phosphorylation APP;CREB1 GO:0007613| memory CREB1;APP GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;APP GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;APP 9396:[DB01183 DB03476] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03476|Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine PLAU common genes common pathways GO:0001666| response to hypoxia CREB1;PLAU GO:0007165| signal transduction PLAU;OPRK1;TLR4;CREB1;ESR1;OPRD1;OPRM1 9397:[DB01183 DB02633] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02633|Cibacron Blue NQO1;GSTP1 common genes common pathways GO:0045471| response to ethanol OPRM1;UGT1A1;NQO1;GSTP1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;GSTP1;TLR4 GO:0043066| negative regulation of apoptotic process GSTP1;ALB;NQO1 GO:0008152| metabolic process CES1;GSTP1;UGT1A1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;NQO1;CYP2C8;GSTP1 GO:0055114| oxidation-reduction process NQO1;CYP2C8;CYP3A4 GO:0043086| negative regulation of catalytic activity UGT1A1;NQO1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0007568| aging NQO1;CREB1 GO:0032355| response to estradiol stimulus ESR1;NQO1;GSTP1 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0098869| ALB;GSTP1 GO:0014070| response to organic cyclic compound UGT1A1;NQO1 GO:0009636| response to toxin CES1;NQO1;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0007584| response to nutrient NQO1;UGT1A1 9398:[DB01183 DB08166] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08166|(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 GO:0006468| protein phosphorylation CREB1;PIM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity PIM1;ESR1 9399:[DB01183 DB06931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;GGPS1 9400:[DB01183 DB01289] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0006811| ion transport SLCO1A2;KCNJ8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;KCNJ8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0051607| defense response to virus OPRK1;KCNJ8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 9401:[DB01183 DB00357] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C19;CYP2C8 GO:0097267| CYP2C8;CYP2C19 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4;CYP11A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP11A1;CYP3A4 GO:0036378| CYP3A4 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0002933| CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP11A1 GO:0060065| uterus development CYP19A1;ESR1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP19A1;CYP2C19;CYP2C8;CYP3A4;CYP11A1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 9402:[DB01183 DB08176] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08176|(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE MAOB common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0009636| response to toxin MAOB;CES1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;MAOB;UGT1A1 GO:0045471| response to ethanol OPRM1;MAOB;UGT1A1;OPRK1 GO:0042493| response to drug CREB1;MAOB;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process MAOB;CYP2C8;CYP3A4 9403:[DB01183 DB13144] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13144|Lenograstim CSF3R common genes common pathways GO:0007165| signal transduction CREB1;CSF3R;TLR4;OPRK1;ESR1;OPRM1;OPRD1 9404:[DB01183 DB08104] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process TTR;ALB 9405:[DB01183 DB00884] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;FDPS GO:0019233| sensory perception of pain OPRM1;PTGS2;OPRD1;OPRK1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1;UGT1A1;TLR4 GO:0006629| lipid metabolic process PTGS2;CYP3A4;FDPS GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;UGT1A1;CREB1 GO:0016032| viral reproduction CREB1;FDPS GO:0006954| inflammatory response TLR4;PTGS2 GO:0007568| aging PTGS2;CREB1 GO:0007613| memory CREB1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;FDPS;CYP3A4 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1;PTGS2 GO:0098869| ALB;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0010033| response to organic substance PTGS2;CREB1;UGT1A1 9406:[DB01183 DB04334] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0055114| oxidation-reduction process AOC3;CYP2C8;CYP3A4 GO:0006954| inflammatory response AOC3;TLR4 GO:0006805| xenobiotic metabolic process AOC3;CYP2C8;CYP3A4;CES1 9407:[DB01183 DB14041] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14041|Fremanezumab CALCA;CALCB common genes common pathways GO:0045087| innate immune response CALCA;TLR4 GO:0050829| defense response to Gram-negative bacterium CALCA;TLR4 GO:0045671| negative regulation of osteoclast differentiation TLR4;CALCA GO:0006468| protein phosphorylation CREB1;CALCA GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;CALCB;CALCA GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CALCB;OPRK1;CREB1;TLR4 GO:0032757| positive regulation of interleukin-8 production CALCA;TLR4 9408:[DB01183 DB07061] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07061|1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL NMT2 common genes common pathways 9409:[DB01183 DB05265] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05265|Ecabet NOXO1;ureC common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOXO1 9410:[DB01183 DB09309] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09309|Kitasamycin CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 9411:[DB01183 DB05479] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05479|CZEN 002 MC1R common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger MC1R;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway MC1R;OPRK1;OPRD1;OPRM1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;MC1R;CREB1;TLR4;OPRK1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;MC1R GO:0045944| positive regulation of transcription from RNA polymerase II promoter MC1R;CREB1;TLR4;ESR1 9412:[DB01183 DB01056] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes ALB common pathways GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0002576| platelet degranulation ALB GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SCN5A;SLCO1A2 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0055085| transmembrane transport SCN5A;SLCO1A2;ABCB1 GO:0098869| ALB GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0006898| receptor-mediated endocytosis ALB GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0051659| maintenance of mitochondrion location ALB GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0043069| negative regulation of programmed cell death ALB 9413:[DB01183 DB04876] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04876|Vildagliptin DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 9414:[DB01183 DB02393] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02393|D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate PFKFB1 common genes common pathways GO:0032868| response to insulin stimulus OPRK1;PFKFB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PFKFB1 GO:0031100| organ regeneration PFKFB1;UGT1A1 GO:0008152| metabolic process CES1;PFKFB1;UGT1A1 GO:0042594| response to starvation PFKFB1;UGT1A1 GO:0033762| response to glucagon stimulus PFKFB1;CREB1 9415:[DB01183 DB08057] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways GO:0045087| innate immune response LCK;TLR4 GO:0042493| response to drug CREB1;UGT1A1;LCK;ABCB1 GO:0016032| viral reproduction CREB1;LCK GO:0006468| protein phosphorylation CREB1;LCK 9416:[DB01183 DB07766] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07766|(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} CAMK2A;CDK16 common genes common pathways GO:0006468| protein phosphorylation CDK16;CAMK2A;CREB1 GO:0030154| cell differentiation CREB1;CDK16;CAMK2A GO:0051092| positive regulation of NF-kappaB transcription factor activity CAMK2A;TLR4 9417:[DB01183 DB11093] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes ALB common pathways GO:0007409| axonogenesis CREB1;S100B;S100A6 GO:0006811| ion transport CACNA1F;RYR2;CACNA1I;CACNA1A;CACNB1;CACNA1E;RYR3;CACNA1S;CATSPER1;TRPV5;CACNA1G;PKD2L1;CACNB3;TRPV6;CACNA1C;RYR1;CACNB4;CACNA1D;SLC8A1;PKD1L3;SLCO1A2;CACNA1H;CACNB2 GO:0014070| response to organic cyclic compound UGT1A1;CASR GO:0034375| high-density lipoprotein particle remodeling ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CIB1;OPRM1 GO:0055085| transmembrane transport CACNA1C;RYR1;CACNA1D;SLC8A1;CALM1;SLCO1A2;CACNA1H;CACNA1F;RYR2;CACNA1A;ABCB1;CACNA1I;CACNA1E;RYR3;CACNA1G;CATSPER1;CACNA1S;TRPV5;TRPV6 GO:0044267| cellular protein metabolic process CALB1;ALB;NUCB1 GO:0001895| retina homeostasis ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0048146| positive regulation of fibroblast proliferation S100A6;ESR1 GO:0001666| response to hypoxia SLC8A1;RYR1;CREB1;RYR2 GO:0010628| positive regulation of gene expression CASR;CALR;TLR4 GO:1904646| CACNA1A;CACNB1;TLR4 GO:0007411| axon guidance CREB1;NRXN1 GO:0007584| response to nutrient SLC8A1;UGT1A1 GO:0008285| negative regulation of cell proliferation CIB1;OPRM1 GO:0010033| response to organic substance CALR;CREB1;UGT1A1;CASQ1 GO:0071363| cellular response to growth factor stimulus CIB1;CREB1;SPARC;OPRD1 GO:0050821| protein stabilization CHP1;CALR;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CALM2;CASR;CALM1;CALM3;OPRM1;OPRD1 GO:0051659| maintenance of mitochondrion location ALB GO:0032355| response to estradiol stimulus ESR1;CALR GO:0051384| response to glucocorticoid stimulus S100B;SPARC;UGT1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB;CADPS2 GO:0071456| cellular response to hypoxia CASR;SLC8A1;S100B;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration SLC8A1;CACNA1C;OPRM1;ESR1;CACNA1A;CIB2 GO:0007613| memory CREB1;S100B GO:0030154| cell differentiation CALR3;TPT1;CIB1;CATSPER1;CREB1 GO:0006810| transport SRI;CACNB4;CACNA1E;CACNB3;ABCB1;CACNA1I;CACNB1 GO:0043069| negative regulation of programmed cell death ALB GO:0007568| aging RGN;CREB1;CANX GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway CASR;OPRD1;OPRM1;OPRK1 GO:0070588| calcium ion transmembrane transport PKD1L3;CACNA1C;RYR1;NCS1;CACNB4;SLC8A1;CACNA1D;CACNB2;CACNA1H;OPRM1;CACNB1;CACNA1F;RYR2;CACNA1A;CACNA1I;CACNB3;TRPV6;CACNA1E;RYR3;PKD2L1;CACNA1G;TRPV5;CACNA1S;CATSPER1 GO:0006898| receptor-mediated endocytosis SPARC;CALR;ALB GO:0035729| cellular response to hepatocyte growth factor stimulus CREB1;CASR GO:0098869| ALB GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0007165| signal transduction TLR4;CREB1;CACNA1I;OPRK1;SRI;OPRD1;OPRM1;ESR1;S100A6;CASR;SPARC GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;RGN GO:0006355| regulation of transcription, DNA-dependent ESR1;CALR;CREB1 GO:0042493| response to drug SLC8A1;ABCB1;CALR;CREB1;UGT1A1 GO:0007268| synaptic transmission CACNB2;OPRM1;NRXN1;OPRD1;CACNB4;CACNB3;CACNA1G;CACNA1E;CACNB1;OPRK1 GO:0043687| post-translational protein modification ALB;NUCB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CIB1;TLR4 GO:0051924| regulation of calcium ion transport SRI;OPRD1;CASR;SLC8A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;SPARC GO:0042060| wound healing SPARC;OPRM1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100A13;S100B;TLR4 GO:0097190| apoptotic signaling pathway TLR4;PDCD6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;CASR;OPRM1;OPRD1;ESR1 GO:0045471| response to ethanol OPRK1;UGT1A1;SPARC;OPRM1 GO:0001889| liver development RGN;UGT1A1 GO:0051481| reduction of cytosolic calcium ion concentration SLC8A1;OPRM1;RYR3 GO:0007626| locomotory behavior CALB1;OPRK1;OPRM1 GO:0002576| platelet degranulation ALB;CALM1;SPARC GO:0043065| positive regulation of apoptotic process S100B;CREB1 GO:0043066| negative regulation of apoptotic process CIB1;ALB;RGN;TPT1 GO:0042981| regulation of apoptotic process CREB1;CALR;TPT1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CALR GO:0045087| innate immune response S100B;TLR4 GO:1990090| CREB1;CIB1 9418:[DB01183 DB08358] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0006468| protein phosphorylation MAPKAPK2;MAPKAPK3;CREB1 GO:0002224| toll-like receptor signaling pathway TLR4;MAPKAPK3;MAPKAPK2 GO:0007165| signal transduction OPRK1;MAPKAPK3;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0000187| activation of MAPK activity TLR4;MAPKAPK3;MAPKAPK2 GO:0032496| response to lipopolysaccharide MAPKAPK2;UGT1A1;MAPKAPK3;TLR4;OPRM1 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process TLR4;MAPKAPK2 GO:0006954| inflammatory response TLR4;MAPKAPK2 9419:[DB01183 DB01354] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;CHRNA4 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;CHRNA4;GRIA2;GRIK2;OPRM1 GO:0007626| locomotory behavior CHRNA4;OPRM1;OPRK1 GO:0007268| synaptic transmission GABRA5;OPRK1;OPRM1;OPRD1;GRIK2;CHRNA4;GRIA2 GO:0035094| response to nicotine CREB1;CHRNA4;CHRNA7 GO:0006810| transport ABCB1;GABRA5;GABRA3;GRIK2;GABRA6;GABRA4;GABRA1 GO:0007613| memory CHRNA7;CREB1 GO:1900273| CHRNA7;CREB1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0007165| signal transduction GRIA2;CHRNA4;CHRNA7;OPRD1;OPRM1;GABRA6;ESR1;OPRK1;GABRA5;TLR4;CREB1 GO:0006811| ion transport GABRA2;GABRA5;GABRA3;CHRNA7;CHRNA4;GRIA2;GRIK2;GABRA6;GABRA4;GABRA1;SLCO1A2 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0055085| transmembrane transport GRIK2;SLCO1A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;TLR4 GO:0001666| response to hypoxia CREB1;CHRNA7;CHRNA4 9420:[DB01183 DB05225] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05225|AM103 ALOX5AP common genes common pathways 9421:[DB01183 DB11948] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11948|Lapachone RBP3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;RBP3 9422:[DB01183 DB03672] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03672|9-N-Phenylmethylamino-Tacrine BCHE common genes common pathways GO:0042493| response to drug BCHE;UGT1A1;CREB1;ABCB1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 9423:[DB01183 DB01255] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;TAAR1;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0006810| transport ABCB1;SLC15A1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction TAAR1;TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0006811| ion transport SLC15A1;SLCO1A2 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO1A2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0007586| digestion UGT1A1;SLC15A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 9424:[DB01183 DB07004] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07004|2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide S100B common genes common pathways GO:0045087| innate immune response S100B;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;S100B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;S100B GO:0007613| memory CREB1;S100B GO:0071456| cellular response to hypoxia OPRD1;S100B GO:0051384| response to glucocorticoid stimulus UGT1A1;S100B GO:0007409| axonogenesis S100B;CREB1 9425:[DB01183 DB04327] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0050821| protein stabilization CREB1;PTEN GO:0032355| response to estradiol stimulus ESR1;PTEN GO:1990314| PTEN;CREB1 GO:0007568| aging PTEN;CREB1 GO:0071456| cellular response to hypoxia PTEN;OPRD1 GO:0007613| memory PTEN;CREB1 GO:0014070| response to organic cyclic compound PTEN;UGT1A1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;PTEN GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PTEN GO:0010628| positive regulation of gene expression TLR4;PTEN GO:0014823| response to activity PTEN;CREB1 GO:0016579| protein deubiquitination PTEN;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;PTEN GO:0010033| response to organic substance CREB1;UGT1A1;PTEN GO:0007584| response to nutrient PTEN;UGT1A1 GO:0045471| response to ethanol UGT1A1;PTEN;OPRK1;OPRM1 GO:0043066| negative regulation of apoptotic process PTEN;ALB GO:0007626| locomotory behavior OPRM1;OPRK1;PTEN GO:0043065| positive regulation of apoptotic process PTEN;CREB1 GO:0071361| cellular response to ethanol UGT1A1;PTEN GO:0006629| lipid metabolic process PTEN;CYP3A4 GO:1990090| CREB1;PTEN GO:0042493| response to drug ABCB1;UGT1A1;PTEN;CREB1 GO:0043491| protein kinase B signaling cascade CREB1;PTEN GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PTEN GO:0042711| maternal behavior PTEN;OPRK1 9426:[DB01183 DB03206] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03206|Duvoglustat MAN1B1;xylA common genes common pathways GO:0008152| metabolic process CES1;MAN1B1;UGT1A1 9427:[DB01183 DB03389] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03389|alpha-D-Xylopyranose LCT common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;LCT 9428:[DB01183 DB08048] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08048|4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL ESR1;NCOA2 common genes ESR1 common pathways GO:1903799| ESR1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0002064| epithelial cell development ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0008584| male gonad development ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;NCOA2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;NCOA2 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 9429:[DB01183 DB08688] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08688|undecan-2-one ACOT13 common genes common pathways 9430:[DB01183 DB06880] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 9431:[DB01183 DB08693] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways GO:0007586| digestion CTRB1;UGT1A1 9432:[DB01183 DB00127] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0051924| regulation of calcium ion transport CASR;OPRD1 GO:0007595| lactation CREB1;XDH GO:0010629| negative regulation of gene expression ESR1;OPRD1;XDH;CREB1 GO:0055114| oxidation-reduction process CYP2C8;SMOX;CYP3A4;XDH GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:1900745| OPRK1;XDH GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;CASR;OPRK1 GO:0010628| positive regulation of gene expression TLR4;CASR GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0014070| response to organic cyclic compound CASR;UGT1A1 GO:0006811| ion transport SLCO1A2;SLC22A4;SLC22A1 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A4;SLCO1A2 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0035729| cellular response to hepatocyte growth factor stimulus CASR;CREB1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0015711| organic anion transport SLC22A4;SLCO1A2;SLC22A1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ADRB1;ESR1;ADRB2;OPRM1;OPRD1;CASR GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB1;CASR;ADRB2;OPRM1;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway CASR;OPRD1;OPRM1;OPRK1 GO:0071456| cellular response to hypoxia CASR;OPRD1 9433:[DB01183 DB07382] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;ERN1;CREB1 GO:0006351| transcription, DNA-dependent ESR1;ERN1;CREB1 GO:0008152| metabolic process UGT1A1;ERN1;CES1 GO:0006468| protein phosphorylation CREB1;ERN1 9434:[DB01183 DB01712] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CREB1 GO:0070588| calcium ion transmembrane transport OPRM1;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TLR4 9435:[DB01183 DB00301] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0036378| CYP3A4 GO:0055085| transmembrane transport ABCB1;SLCO1A2;ABCB11 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;ALB GO:0042359| vitamin D metabolic process CYP3A4 GO:0006810| transport ABCB11;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 9436:[DB01183 DB00547] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00547|Desoximetasone NR3C1 common genes common pathways GO:0006351| transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0007165| signal transduction OPRM1;NR3C1;OPRD1;ESR1;CREB1;TLR4;OPRK1 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 9437:[DB01183 DB00868] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00868|Benzonatate SCN5A common genes common pathways GO:0006811| ion transport SLCO1A2;SCN5A GO:0055085| transmembrane transport ABCB1;SCN5A;SLCO1A2 9438:[DB01183 DB07795] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07795|Fisetin CDK6 common genes common pathways GO:0048146| positive regulation of fibroblast proliferation CDK6;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;CDK6 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CDK6;CREB1;TLR4;OPRK1 GO:0014002| astrocyte development CDK6;TLR4 GO:0030154| cell differentiation CREB1;CDK6 GO:0006468| protein phosphorylation CREB1;CDK6 9439:[DB01183 DB03096] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03096|N-Aminoethylmorpholine CTSD common genes common pathways 9440:[DB01183 DB12731] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12731|Daporinad NAMPT common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;OPRK1;NAMPT GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;NAMPT GO:0048511| rhythmic process NAMPT;CREB1 GO:0014070| response to organic cyclic compound NAMPT;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NAMPT;ESR1 GO:0007623| circadian rhythm CREB1;NAMPT 9441:[DB01183 DB07201] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport ABCB1;TTR 9442:[DB01183 DB05077] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05077|SLV319 CNR1 common genes common pathways GO:0007165| signal transduction ESR1;CNR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CNR1;OPRD1;OPRM1 GO:0007613| memory CNR1;CREB1 GO:0007568| aging CNR1;CREB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR1 GO:0007584| response to nutrient CNR1;UGT1A1 GO:0042220| response to cocaine CNR1;OPRM1;OPRK1 GO:0043065| positive regulation of apoptotic process CNR1;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;CNR1;UGT1A1;TLR4 GO:0045471| response to ethanol OPRM1;CNR1;OPRK1;UGT1A1 GO:0019233| sensory perception of pain OPRM1;OPRD1;CNR1;OPRK1 GO:0043278| response to morphine CNR1;OPRM1;OPRK1 GO:0035094| response to nicotine CNR1;CREB1 9443:[DB01183 DB05446] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05446|LJP 1082 APOH common genes common pathways GO:0002576| platelet degranulation APOH;ALB 9444:[DB01183 DB06963] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;PLK1 GO:0071168| protein localization to chromatin ESR1;PLK1 GO:0006468| protein phosphorylation PLK1;CREB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 9445:[DB01183 DB00893] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0002576| platelet degranulation TF;ALB GO:0043687| post-translational protein modification TF;ALB GO:0055114| oxidation-reduction process FTH1;CYP3A4;CYP2C8 GO:0006955| immune response OPRK1;TLR4;FTH1;OPRD1 GO:0098869| ALB;HBB;HBA1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;HBB;TLR4 GO:0006898| receptor-mediated endocytosis HBB;HBA1;ALB GO:0006811| ion transport SLCO1A2;TF GO:0001895| retina homeostasis ALB;TF GO:0044267| cellular protein metabolic process TF;ALB GO:0008285| negative regulation of cell proliferation FTH1;OPRM1 9446:[DB01183 DB00128] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ASPH;ESR1 GO:0051607| defense response to virus OPRK1;RNASE1 GO:0007268| synaptic transmission OPRM1;OPRD1;SLC1A1;OPRK1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;ASPH GO:0042742| defense response to bacterium TLR4;LYZ GO:0016032| viral reproduction ACY3;CREB1 GO:0006954| inflammatory response LYZ;TLR4 GO:0007595| lactation CAD;CREB1 GO:0007623| circadian rhythm CREB1;ASS1 GO:0001889| liver development CAD;UGT1A1;ASNS GO:0045471| response to ethanol OPRK1;UGT1A1;GOT2;OPRM1 GO:0043066| negative regulation of apoptotic process ASNS;ALB GO:0006805| xenobiotic metabolic process ACY3;CYP2C8;CYP3A4;CES1;ACY1 GO:0008152| metabolic process PAICS;ACY1;CES1;CAD;LYZ;ASPA;UGT1A1;ACY3 GO:0050829| defense response to Gram-negative bacterium LYZ;TLR4 GO:0042594| response to starvation ADSSL1;CAD;UGT1A1 GO:0009636| response to toxin CES1;ASNS GO:0006811| ion transport SLC1A1;SLCO1A2 GO:0044267| cellular protein metabolic process ALB;LYZ GO:0001895| retina homeostasis LYZ;ALB GO:0055085| transmembrane transport SLCO1A2;SLC25A13;SLC16A10;SLC25A12;ABCB1 GO:0032868| response to insulin stimulus CAD;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;ASPH GO:0051384| response to glucocorticoid stimulus UGT1A1;GOT1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;ASS1;TLR4 GO:0032870| cellular response to hormone stimulus ASNS;UGT1A1 GO:0070588| calcium ion transmembrane transport ASPH;OPRM1 GO:0031100| organ regeneration UGT1A1;CAD GO:0002376| immune system process TLR4;ADSSL1;ADSS GO:0017144| drug metabolic process CYP3A4;CYP2C8;CAD;UGT1A1 9447:[DB01183 DB06321] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06321|R-348 JAK3 common genes common pathways GO:0002376| immune system process TLR4;JAK3 GO:0006468| protein phosphorylation CREB1;JAK3 GO:0006954| inflammatory response TLR4;JAK3 GO:0042981| regulation of apoptotic process ESR1;JAK3;CREB1 GO:0045087| innate immune response JAK3;TLR4 9448:[DB01183 DB02281] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02281|Formycin MTAP common genes common pathways 9449:[DB01183 DB02598] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0001666| response to hypoxia PAM;CREB1 GO:0032355| response to estradiol stimulus PAM;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PAM GO:0042493| response to drug ABCB1;UGT1A1;PAM;CREB1 GO:0055114| oxidation-reduction process PAM;CYP2C8;CYP3A4 GO:0007595| lactation PAM;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter PAM;ESR1 GO:0008152| metabolic process PAM;UGT1A1;CES1 9450:[DB01183 DB05209] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05209|SYM001 RHD common genes common pathways 9451:[DB01183 DB04437] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04437|Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline FABP4 common genes common pathways GO:0050729| positive regulation of inflammatory response FABP4;TLR4 GO:0050727| regulation of inflammatory response TLR4;ESR1;FABP4 9452:[DB01183 DB14639] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14639|Boldenone undecylenate AR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0016579| protein deubiquitination AR;ESR1 GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction AR;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 9453:[DB01183 DB06802] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory PTGS2;CREB1 GO:0007568| aging PTGS2;CREB1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0098869| ALB;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;PTGS2;ESR1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0010033| response to organic substance PTGS2;UGT1A1;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;OPRK1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1;TLR4;UGT1A1 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0050727| regulation of inflammatory response TLR4;PTGS2;ESR1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;PTGS1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2;PTGS1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2;TLR4 9454:[DB01183 DB01764] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01764|Dalfopristin vatD;CYP3A4 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 9455:[DB01183 DB00797] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0006954| inflammatory response TLR4;HRH1 GO:0006955| immune response OPRD1;HRH2;OPRK1;TLR4 GO:0008542| visual learning HRH2;HRH1;CREB1 GO:0042493| response to drug ADRA1A;ABCB1;UGT1A1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;OPRM1;OPRD1;HRH1;ESR1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HRH2;OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1;ADRA2C GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0007165| signal transduction ADRA2A;OPRK1;ADRA1A;CREB1;TLR4;ESR1;ADRA2C;HRH2;ADRA2B;OPRM1;HRH1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRA2A;OPRK1;OPRM1;HRH1;OPRD1;ADRA2C;HRH2;ADRA2B GO:0007613| memory CREB1;HRH1;HRH2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;ADRA1A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1 GO:0007568| aging CREB1;ADRA1A 9456:[DB01183 DB00345] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes SLCO1A2 common pathways GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;ABCC2 GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABCC2;TLR4 GO:0032094| response to food SLC16A1;OPRM1 GO:0042493| response to drug CREB1;UGT1A1;ABCC1;ABCC2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A11;SLC22A7;SLCO1B1;SLC22A8;SLCO3A1;SLCO1A2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0015711| organic anion transport SLC22A7;SLC22A11;SLC22A4;SLCO1A2;SLC22A5;SLCO1B1;SLC22A2;SLC22A6 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCC2;ABCB1;SLC22A5 GO:0055085| transmembrane transport SLC22A4;SLCO3A1;SLCO1A2;SLC22A5;SLC22A8;SLCO1B1;SLC22A11;SLC16A1;SLC22A7;ABCC1;SLC22A6;ABCB1;SLC22A2;ABCC2 GO:0009636| response to toxin SLC22A8;CES1 GO:0006811| ion transport SLC22A7;SLC22A11;SLC22A5;SLC22A8;SLCO1B1;SLC22A4;SLCO3A1;SLCO1A2;SLC22A2 GO:0043627| response to estrogen stimulus ESR1;OPRK1;ABCC2 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;ALB 9457:[DB01183 DB02783] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways GO:0045471| response to ethanol OPRM1;OPRK1;GOT2;UGT1A1 9458:[DB01183 DB07628] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07628|6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one PKM common genes common pathways GO:0032868| response to insulin stimulus PKM;OPRK1 GO:0010033| response to organic substance CREB1;UGT1A1;PKM GO:0007584| response to nutrient PKM;UGT1A1 GO:0001666| response to hypoxia PKM;CREB1 GO:0031100| organ regeneration PKM;UGT1A1 GO:0001889| liver development PKM;UGT1A1 GO:0008152| metabolic process CES1;PKM;UGT1A1 9459:[DB01183 DB07895] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07895|ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID FNTB;FNTA common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FNTA 9460:[DB01183 DB06444] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06444|Dexanabinol TNF common genes common pathways GO:0010628| positive regulation of gene expression TNF;TLR4 GO:0010033| response to organic substance TNF;CREB1;UGT1A1 GO:0000187| activation of MAPK activity TLR4;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;TNF;ESR1;OPRM1 GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0006955| immune response OPRK1;TLR4;TNF;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF GO:0006954| inflammatory response TLR4;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0045893| positive regulation of transcription, DNA-dependent ESR1;TNF;CREB1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0010629| negative regulation of gene expression ESR1;OPRD1;TNF;CREB1 GO:0042742| defense response to bacterium TLR4;TNF GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;TNF;CREB1;ESR1 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;OPRK1 GO:0043065| positive regulation of apoptotic process TNF;CREB1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0050727| regulation of inflammatory response ESR1;TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0046330| positive regulation of JNK cascade TNF;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0097190| apoptotic signaling pathway TNF;TLR4 9461:[DB01183 DB05595] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05595|Farletuzumab FOLR1 common genes common pathways GO:0006898| receptor-mediated endocytosis FOLR1;ALB 9462:[DB01183 DB08174] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08174|5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways 9463:[DB01183 DB06103] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06103|VX-148 IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;IMPDH1;IMPDH2;CYP3A4 GO:0007623| circadian rhythm IMPDH2;CREB1 9464:[DB01183 DB00061] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00061|Pegademase bovine GRB2 common genes common pathways GO:0030154| cell differentiation CREB1;GRB2 GO:0007568| aging CREB1;GRB2 GO:0007411| axon guidance GRB2;CREB1 GO:0045087| innate immune response GRB2;TLR4 GO:0016032| viral reproduction GRB2;CREB1 9465:[DB01183 DB07002] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0009617| response to bacterium NOS2;TLR4 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS2 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0007623| circadian rhythm CREB1;NOS2 GO:0032496| response to lipopolysaccharide UGT1A1;NOS2;TLR4;OPRM1 9466:[DB01183 DB01113] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01113|Papaverine PDE4B;PDE10A common genes common pathways GO:0007165| signal transduction CREB1;TLR4;PDE4B;OPRK1;OPRM1;OPRD1;ESR1;PDE10A GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PDE10A;PDE4B;OPRK1 GO:0071222| cellular response to lipopolysaccharide TLR4;PDE4B;OPRK1 GO:0008152| metabolic process UGT1A1;CES1;PDE10A GO:0032729| positive regulation of interferon-gamma production PDE4B;TLR4 9467:[DB01183 DB07364] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways GO:0008542| visual learning CREB1;CDK5 GO:1901215| CDK5;CREB1 GO:0007268| synaptic transmission OPRK1;CDK5;OPRD1;OPRM1 GO:0042981| regulation of apoptotic process CDK5;CREB1;ESR1 GO:0048148| behavioral response to cocaine CDK5;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CDK5 GO:0019233| sensory perception of pain CDK5;OPRK1;OPRD1;OPRM1 GO:0007411| axon guidance CREB1;CDK5R1 GO:0048511| rhythmic process CDK5R1;CDK5;CREB1 GO:1904646| CDK5;TLR4 GO:0042220| response to cocaine OPRM1;CDK5;OPRK1 GO:0007409| axonogenesis CREB1;CDK5 GO:0006468| protein phosphorylation CREB1;CDK5 9468:[DB01183 DB05758] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05758|CYT007-TNFQb TNF common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0032757| positive regulation of interleukin-8 production TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;TNF;OPRM1;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0010033| response to organic substance UGT1A1;TNF;CREB1 GO:0010628| positive regulation of gene expression TLR4;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TNF;TLR4 GO:0000187| activation of MAPK activity TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;TNF;CREB1;ESR1 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;OPRK1 GO:0043065| positive regulation of apoptotic process TNF;CREB1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0006954| inflammatory response TLR4;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0006955| immune response OPRD1;TNF;TLR4;OPRK1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF GO:0042742| defense response to bacterium TLR4;TNF GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0010629| negative regulation of gene expression CREB1;TNF;ESR1;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;CREB1;ESR1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 9469:[DB01183 DB07081] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9470:[DB01183 DB06495] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06495|Onercept TNF common genes common pathways GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0032757| positive regulation of interleukin-8 production TNF;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;OPRM1 GO:0000187| activation of MAPK activity TNF;TLR4 GO:0010033| response to organic substance UGT1A1;TNF;CREB1 GO:0010628| positive regulation of gene expression TNF;TLR4 GO:0097190| apoptotic signaling pathway TNF;TLR4 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0032729| positive regulation of interferon-gamma production TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TNF GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0043065| positive regulation of apoptotic process CREB1;TNF GO:0071222| cellular response to lipopolysaccharide TLR4;TNF;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNF;TLR4;CREB1 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0042742| defense response to bacterium TLR4;TNF GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;TNF GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;TNF;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0006954| inflammatory response TNF;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;ESR1 GO:0006955| immune response OPRD1;OPRK1;TNF;TLR4 9471:[DB01183 DB01897] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;HPGDS;TLR4;CREB1;OPRK1 GO:0006629| lipid metabolic process CYP3A4;HPGDS GO:0007626| locomotory behavior OPRK1;HPGDS;OPRM1 9472:[DB01183 DB11471] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11471|Tilmicosin CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 9473:[DB01183 DB08067] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways GO:0042981| regulation of apoptotic process JAK2;CREB1;ESR1 GO:0045087| innate immune response JAK2;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;JAK2 GO:0050727| regulation of inflammatory response ESR1;TLR4;JAK2 GO:0032496| response to lipopolysaccharide UGT1A1;JAK2;TLR4;OPRM1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;JAK2 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;JAK2;CREB1;TLR4 GO:0002376| immune system process JAK2;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;JAK2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration JAK2;ESR1;OPRM1 GO:0030154| cell differentiation CREB1;JAK2 GO:0006468| protein phosphorylation JAK2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway JAK2;OPRK1;OPRD1;OPRM1 GO:0050729| positive regulation of inflammatory response JAK2;TLR4 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process JAK2;TLR4 GO:0008285| negative regulation of cell proliferation JAK2;OPRM1 9474:[DB01183 DB02342] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0008210| estrogen metabolic process COMT;UGT1A1;CYP1B1 GO:0007595| lactation CREB1;HIF1A GO:0008542| visual learning CREB1;HIF1A GO:0042493| response to drug CYP1A1;CREB1;UGT1A1;COMT;ABCB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;HIF1A;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HIF1A;ESR1 GO:0032094| response to food OPRM1;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;HIF1A;CREB1 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0043687| post-translational protein modification ALB;HIF1A GO:0055114| oxidation-reduction process CYP1A1;CYP19A1;CYP1B1;CYP2C8;CYP3A4 GO:0043065| positive regulation of apoptotic process CREB1;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HIF1A;ESR1;TLR4;CREB1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C8;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8;CYP1B1 GO:0043066| negative regulation of apoptotic process ALB;HIF1A GO:0060065| uterus development CYP19A1;ESR1 GO:1903715| HIF1A;OPRK1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;COMT;CYP1A1;TLR4 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HIF1A GO:0006351| transcription, DNA-dependent CREB1;HIF1A;ESR1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0010628| positive regulation of gene expression HIF1A;TLR4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia HIF1A;CYP1A1;CREB1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;COMT GO:0016579| protein deubiquitination HIF1A;ESR1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A1 GO:0008285| negative regulation of cell proliferation CYP1B1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;COMT;OPRK1 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0002933| CYP1A1;CYP2C8;CYP3A4 GO:0009636| response to toxin CYP1A1;CYP1B1;CES1 GO:0014070| response to organic cyclic compound UGT1A1;COMT;CYP1A1 GO:0006366| transcription from RNA polymerase II promoter CREB1;HIF1A;ESR1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;HIF1A GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP2C8;CYP3A4 GO:0097267| CYP1A1;CYP1B1;CYP2C8 GO:0032722| positive regulation of chemokine production TLR4;HIF1A GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP1B1;CYP1A1;UGT1A1 GO:0030154| cell differentiation HIF1A;CREB1 GO:0071456| cellular response to hypoxia HIF1A;OPRD1 GO:0007568| aging CREB1;CYP1A1 9475:[DB01183 DB14502] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;TLR4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;SLC34A1 GO:0016032| viral reproduction CREB1;SLC20A2 GO:0032355| response to estradiol stimulus SLC34A1;ESR1 GO:0006810| transport SLC20A1;SLC20A2;ABCB1 GO:0007165| signal transduction OPRM1;OPRD1;SLC20A1;ESR1;OPRK1;CREB1;TLR4 GO:0006811| ion transport SLC34A2;SLC20A2;SLC34A3;SLC34A1;SLC20A1;SLCO1A2 GO:0044267| cellular protein metabolic process SLC34A2;ALB;SLC34A1 GO:0055085| transmembrane transport SLC34A3;SLC20A2;SLCO1A2;SLC20A1;SLC34A2;ABCB1 GO:0043627| response to estrogen stimulus ESR1;SLC34A2;OPRK1 GO:0007584| response to nutrient SLC34A1;UGT1A1 9476:[DB01183 DB02417] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02417|2,4,6-Tribromophenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process TTR;ALB 9477:[DB01183 DB14013] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14013|SR-9009 NR1D1;NR1D2 common genes common pathways GO:0030154| cell differentiation CREB1;NR1D1 GO:0048511| rhythmic process NR1D1;CREB1;NR1D2 GO:0071222| cellular response to lipopolysaccharide OPRK1;NR1D1;TLR4 GO:0050727| regulation of inflammatory response TLR4;NR1D2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1D1;ESR1;NR1D2 GO:0007623| circadian rhythm NR1D1;CREB1 GO:0006351| transcription, DNA-dependent NR1D2;ESR1;CREB1;NR1D1 GO:0043401| steroid hormone mediated signaling pathway NR1D1;NR1D2;ESR1 GO:0042752| regulation of circadian rhythm NR1D2;NR1D1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1D1;NR1D2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR1D1;ESR1;NR1D2 GO:2000505| regulation of energy homeostasis OPRK1;NR1D2 GO:0006355| regulation of transcription, DNA-dependent NR1D2;ESR1;CREB1;NR1D1 9478:[DB01183 DB07410] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;GGPS1 9479:[DB01183 DB03542] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways GO:0007165| signal transduction IMPA1;OPRK1;TLR4;CREB1;ESR1;OPRD1;OPRM1 9480:[DB01183 DB00507] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00507|Nitazoxanide SLC19A1 common genes common pathways 9481:[DB01183 DB07776] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESRRB;ESRRA GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESRRA;ESRRB GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter ESRRB;ESRRA;ESR1 GO:0006351| transcription, DNA-dependent ESR1;ESRRA;ESRRB;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESRRB;ESRRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRA;ESRRB;ESR1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C8;CYP3A4;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;ESRRA;ESRRB GO:0043065| positive regulation of apoptotic process CYP1B1;CREB1 GO:0009636| response to toxin CES1;CYP1B1 GO:0008285| negative regulation of cell proliferation OPRM1;CYP1B1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP1B1 GO:0032355| response to estradiol stimulus ESR1;ESRRA GO:0097267| CYP1B1;CYP2C8 9482:[DB01183 DB06689] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2E1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP2E1 GO:0045087| innate immune response TLR4;F12 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;CYP3A4;CYP2C8 GO:0045471| response to ethanol OPRM1;CYP2E1;UGT1A1;OPRK1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2E1 9483:[DB01183 DB00922] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0055085| transmembrane transport KCNJ11;SLCO1A2;ABCB1 GO:0006811| ion transport KCNJ8;SLCO1A2;KCNJ11 GO:0032355| response to estradiol stimulus ESR1;KCNJ11 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE3A;OPRD1;OPRM1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4;PDE3A GO:0042493| response to drug KCNJ11;ABCB1;UGT1A1;PDE3A;CREB1 GO:0051607| defense response to virus KCNJ8;OPRK1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;KCNJ8 GO:0006629| lipid metabolic process CYP3A4;PDE3A GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PDE3A GO:0043066| negative regulation of apoptotic process ALB;PDE3A 9484:[DB01183 DB01176] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0045600| positive regulation of fat cell differentiation SULT1E1;CREB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;HRH1;OPRD1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 GO:0097267| CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HRH1;OPRD1;OPRM1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;SULT1E1;CYP2C9;CYP2C8 GO:0008210| estrogen metabolic process SULT1E1;UGT1A1 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;HRH1;OPRD1 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 9485:[DB01183 DB09328] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;FADS1;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent FADS1;CREB1;ESR1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2;CYP2E1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0001889| liver development UGT1A1;ACAT1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process ELOVL4;FADS1;ACAA1;CYP3A4;CYP1A2 GO:0042594| response to starvation ACAT1;UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C8 GO:0008152| metabolic process ACAT1;ACAA1;CES1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP2E1;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound ACAT1;CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;UGT1A1;CYP2C8 GO:0009267| cellular response to starvation ALB;FADS1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C8;UGT1A1 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 9486:[DB01183 DB03597] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways GO:0008152| metabolic process CES1;GSTM4;UGT1A1;PDE5A GO:0007165| signal transduction OPRK1;PDE9A;TLR4;CREB1;PDE5A;ESR1;OPRD1;OPRM1 9487:[DB01183 DB04857] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04857|Brasofensine DRD2 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0042220| response to cocaine OPRK1;DRD2;OPRM1 GO:0007409| axonogenesis DRD2;CREB1 GO:0009636| response to toxin DRD2;CES1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;OPRD1;OPRM1 GO:0007165| signal transduction OPRK1;DRD2;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:1900273| DRD2;CREB1 GO:0042493| response to drug DRD2;ABCB1;CREB1;UGT1A1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0035094| response to nicotine DRD2;CREB1 GO:0043278| response to morphine OPRM1;DRD2;OPRK1 GO:0008542| visual learning DRD2;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol UGT1A1;OPRK1;DRD2;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD2 GO:0007626| locomotory behavior OPRM1;OPRK1;DRD2 GO:0048148| behavioral response to cocaine DRD2;OPRK1 9488:[DB01183 DB02661] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways GO:0008152| metabolic process CES1;PAPSS1;UGT1A1 9489:[DB01183 DB08229] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0043065| positive regulation of apoptotic process CREB1;CASP3 GO:0032496| response to lipopolysaccharide OPRM1;CASP3;UGT1A1;TLR4 GO:0042060| wound healing CASP3;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;CASP3 GO:0035094| response to nicotine CREB1;CASP3 GO:0042493| response to drug CASP3;ABCB1;UGT1A1;CREB1 GO:0032355| response to estradiol stimulus ESR1;CASP3 GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0001666| response to hypoxia CASP3;CREB1 GO:0010033| response to organic substance CASP3;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound CASP3;UGT1A1 9490:[DB01183 DB02079] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02079|Aminooxyacetic acid AGXT common genes common pathways GO:0051384| response to glucocorticoid stimulus AGXT;UGT1A1 9491:[DB01183 DB05524] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05524|Pelitinib EGFR common genes common pathways GO:0007623| circadian rhythm CREB1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1 GO:0042060| wound healing EGFR;OPRM1 GO:0001889| liver development UGT1A1;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;EGFR;ESR1 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1 GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0071363| cellular response to growth factor stimulus EGFR;CREB1;OPRD1 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0006468| protein phosphorylation CREB1;EGFR GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TLR4;OPRM1;ESR1 GO:0007165| signal transduction EGFR;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;EGFR;OPRM1 GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 9492:[DB01183 DB11155] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP1B1;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8;CYP1B1 GO:0043065| positive regulation of apoptotic process CYP1B1;CREB1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;TLR4;OPRM1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0032094| response to food OPRM1;CYP1A1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP1B1;CYP1A1;CYP3A4 GO:0097267| CYP1A1;CYP2C8;CYP1B1 GO:0017144| drug metabolic process CYP3A4;CYP1A1;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP1B1;CYP2C8;CYP3A4 GO:0007568| aging CYP1A1;CREB1 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008285| negative regulation of cell proliferation CYP1B1;OPRM1 GO:0010033| response to organic substance CYP1A1;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0009636| response to toxin CYP1B1;CYP1A1;CES1 GO:0002933| CYP1A1;CYP2C8;CYP3A4 9493:[DB01183 DB00348] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00348|Nitisinone HPD common genes common pathways GO:0055114| oxidation-reduction process HPD;CYP2C8;CYP3A4 9494:[DB01183 DB11644] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11644|Tafamidis TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0044267| cellular protein metabolic process ALB;TTR 9495:[DB01183 DB11751] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLCO1A2;SLC22A6;ABCB1 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB;SLC22A6 9496:[DB01183 DB02076] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways GO:0032355| response to estradiol stimulus ESR1;GPI GO:0043278| response to morphine OPRM1;OPRK1;GPI GO:0055114| oxidation-reduction process CYP3A4;PGD;CYP2C8 9497:[DB01183 DB08373] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways GO:0051384| response to glucocorticoid stimulus SCGB1A1;UGT1A1 GO:0007165| signal transduction OPRD1;SCGB1A1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0032689| negative regulation of interferon-gamma production TLR4;SCGB1A1 GO:0010033| response to organic substance UGT1A1;CREB1;SCGB1A1 GO:0032496| response to lipopolysaccharide OPRM1;SCGB1A1;UGT1A1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;SCGB1A1 GO:0050727| regulation of inflammatory response TLR4;SCGB1A1;ESR1 GO:0042493| response to drug SCGB1A1;UGT1A1;CREB1;ABCB1 GO:0043086| negative regulation of catalytic activity SCGB1A1;UGT1A1 9498:[DB01183 DB04911] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2D6;CYP2C8;CYP2C19 GO:0097267| CYP2C9;CYP2C19;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2C8;CYP2C19;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP2C9;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;UGT1A1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9 GO:0006706| steroid catabolic process CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2C9;CES1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2C9 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C19;CYP2C8 9499:[DB01183 DB01338] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01338|Pipecuronium CHRNA2;CHRM2;CHRM3;BCHE common genes common pathways GO:0042493| response to drug ABCB1;CREB1;BCHE;UGT1A1 GO:0035094| response to nicotine CHRNA2;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;OPRM1 GO:0007586| digestion UGT1A1;CHRM3 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway CHRM2;OPRM1;OPRD1;CHRM3;OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRM2;CHRNA2;CHRM3;CREB1;TLR4;OPRK1 9500:[DB01183 DB06475] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06475|Ruplizumab CD40LG common genes common pathways GO:0006955| immune response OPRD1;CD40LG;TLR4;OPRK1 GO:0006954| inflammatory response CD40LG;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CD40LG GO:0032733| positive regulation of interleukin-10 production TLR4;CD40LG GO:0043066| negative regulation of apoptotic process CD40LG;ALB GO:0032735| positive regulation of interleukin-12 production CD40LG;TLR4 9501:[DB01183 DB04659] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04659|(1S,2S,3R,4S,5S)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways GO:0008152| metabolic process UGT1A1;LCT;CES1 9502:[DB01183 DB04912] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04912|Stannsoporfin HMOX1;HMOX2 common genes common pathways GO:0042167| heme catabolic process HMOX2;UGT1A1;HMOX1 GO:0071456| cellular response to hypoxia HMOX1;OPRD1 GO:0001666| response to hypoxia HMOX1;CREB1;HMOX2 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HMOX1 GO:0043627| response to estrogen stimulus HMOX1;ESR1;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HMOX1 GO:0043065| positive regulation of apoptotic process CREB1;HMOX1 GO:0055114| oxidation-reduction process CYP2C8;HMOX2;HMOX1;CYP3A4 GO:0035094| response to nicotine HMOX1;CREB1 9503:[DB01183 DB03642] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03642|Benzofuran-2-Carboxylic Acid {(S)-3-Methyl-1-[3-Oxo-1-(Pyridin-2-Ylsulfonyl)Azepan-4-Ylcarbamoyl]Butyl}Amide CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway CTSK;TLR4 9504:[DB01183 DB01097] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C9;UGT1A1 GO:0030154| cell differentiation CREB1;PTK2B GO:0006468| protein phosphorylation PTK2B;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration PTK2B;ESR1;OPRM1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0002376| immune system process PTK2B;TLR4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8;CYP2C9 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;PTK2B GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1;PTK2B GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1;CYP2C9 GO:0097267| CYP2C8;CYP2C9;CYP1A2 GO:0009636| response to toxin AHR;CES1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;DHODH GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;AHR;ESR1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCG2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;PTK2B;TLR4 GO:0042220| response to cocaine OPRM1;OPRK1;PTK2B GO:0001666| response to hypoxia CREB1;PTK2B GO:0048511| rhythmic process AHR;CREB1 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PTK2B GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP1A2 GO:0045471| response to ethanol OPRM1;OPRK1;PTK2B;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;PTK2B GO:0046330| positive regulation of JNK cascade TLR4;PTK2B GO:0006351| transcription, DNA-dependent AHR;CREB1;ESR1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity PTK2B;OPRM1 GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;AHR GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;AHR;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP1A2 GO:0043066| negative regulation of apoptotic process PTK2B;ALB GO:0045087| innate immune response TLR4;PTK2B GO:0042594| response to starvation UGT1A1;DHODH GO:0006629| lipid metabolic process CYP2C9;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042493| response to drug PTK2B;ABCG2;ABCB1;CREB1;UGT1A1;DHODH;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C9 GO:0006355| regulation of transcription, DNA-dependent CREB1;AHR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AHR;CREB1 GO:0055114| oxidation-reduction process DHODH;CYP3A4;CYP1A2;CYP2C8;CYP2C9 GO:0007595| lactation DHODH;CREB1 9505:[DB01183 DB00670] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00670|Pirenzepine CHRM1 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;CHRM1;ESR1;OPRK1;TLR4;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;CHRM1 9506:[DB01183 DB04878] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04878|Voglibose MGAM common genes common pathways GO:0008152| metabolic process UGT1A1;MGAM;CES1 9507:[DB01183 DB00113] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;CEACAM1;ALB 9508:[DB01183 DB11132] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11132|Silicon dioxide MARCO common genes common pathways GO:0045087| innate immune response TLR4;MARCO GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MARCO;TLR4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;MARCO;OPRK1 GO:0002376| immune system process TLR4;MARCO GO:0006898| receptor-mediated endocytosis MARCO;ALB 9509:[DB01183 DB02048] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02048|1,2,4-Triazole-Carboxamidine NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 9510:[DB01183 DB09237] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes CYP3A4 common pathways GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0001666| response to hypoxia CREB1;NOS2 GO:0055085| transmembrane transport SLCO1A2;CACNA1C;ABCB1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0006811| ion transport SLCO1A2;CACNA1C GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070588| calcium ion transmembrane transport CACNA1C;OPRM1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration CACNA1C;OPRM1;ESR1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0009617| response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process NOS3;CYP2C8;NOS2;CYP3A4 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;NOS2 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0007623| circadian rhythm CREB1;NOS2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;NOS2;UGT1A1 9511:[DB01183 DB04368] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04368|Bb-3497 def;PDF common genes common pathways 9512:[DB01183 DB03273] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03273|3'-Oxo-Adenosine AHCY common genes common pathways GO:0001666| response to hypoxia AHCY;CREB1 GO:0007584| response to nutrient UGT1A1;AHCY 9513:[DB01183 DB04214] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 9514:[DB01183 DB05382] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05382|Iodine MT-ND5 common genes common pathways GO:0001666| response to hypoxia MT-ND5;CREB1 GO:0055114| oxidation-reduction process MT-ND5;CYP2C8;CYP3A4 9515:[DB01183 DB02490] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 9516:[DB01183 DB02106] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;THRB GO:0060509| Type I pneumocyte differentiation THRB;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;THRB;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0043401| steroid hormone mediated signaling pathway THRB;ESR1 GO:0006351| transcription, DNA-dependent ESR1;THRB;CREB1 9517:[DB01183 DB07702] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07702|17alpha-Estriol NCOA5;ESR2 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;ESR2 GO:0006351| transcription, DNA-dependent ESR1;CREB1;NCOA5;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA5;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 9518:[DB01183 DB02730] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02730|4-Methylthio-Alpha-D-Mannose AMY2B common genes common pathways GO:0008152| metabolic process UGT1A1;AMY2B;CES1 GO:0007586| digestion AMY2B;UGT1A1 9519:[DB01183 DB00463] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0001666| response to hypoxia CHRNA7;CHRNA4;CREB1 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0055085| transmembrane transport GRIK2;SLCO1A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CHRNA7;TLR4 GO:0009636| response to toxin CES1;GABRB1 GO:0006811| ion transport GABRA6;GRIK2;GABRA4;GABRA1;GABRE;GABRQ;GABRB1;GABRG2;SLCO1A2;GABRB3;CHRNA7;GABRG3;GRIA2;CHRNA4;GABRD;GABRB2;GABRP;GABRG1;GABRA3;GABRA5;GABRA2 GO:0007165| signal transduction GABRA5;GABRD;CREB1;GABRP;TLR4;OPRK1;OPRM1;GABRE;GABRB1;OPRD1;GABRQ;GABRA6;ESR1;GRIA2;CHRNA4;GABRB3;CHRNA7 GO:1900273| CREB1;CHRNA7 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0006810| transport GABRD;GABRB2;GABRA3;GABRA5;ABCB1;GABRA1;GABRA4;GABRA6;GRIK2;GABRB1;GABRG2;GABRB3 GO:0007613| memory CHRNA7;CREB1 GO:0035094| response to nicotine CHRNA4;CHRNA7;CREB1 GO:1901215| GABRB2;CREB1;GABRB3 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;GABRG3 GO:0007268| synaptic transmission GABRA5;GABRG1;GABRD;GABRB2;OPRK1;GABRG2;OPRD1;OPRM1;GRIK2;GRIA2;CHRNA4 GO:0007626| locomotory behavior OPRM1;CHRNA4;OPRK1 GO:0019233| sensory perception of pain OPRM1;OPRD1;CHRNA4;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIK2;CHRNA4;GRIA2;CHRNA7 9520:[DB01183 DB00680] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00680|Moricizine SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A;SLCO1A2 GO:0006811| ion transport SCN5A;SLCO1A2 9521:[DB01183 DB08035] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development ESR1;AR GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0016579| protein deubiquitination AR;ESR1 GO:0006810| transport ABCB1;AR GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;AR 9522:[DB01183 DB03338] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0045600| positive regulation of fat cell differentiation PPARD;CREB1 GO:0010033| response to organic substance UGT1A1;CREB1;PPARD GO:0014823| response to activity PPARD;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FKBP1A GO:0070588| calcium ion transmembrane transport OPRM1;FKBP1A GO:0030154| cell differentiation CREB1;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARD;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARD;CREB1 GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0071222| cellular response to lipopolysaccharide PPARD;OPRK1;TLR4 GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0042060| wound healing PPARD;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARD GO:0006351| transcription, DNA-dependent CREB1;ESR1;PPARD GO:0097190| apoptotic signaling pathway TLR4;PPARD GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A 9523:[DB01183 DB00579] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0009636| response to toxin SLC6A4;SLC18A2;CES1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3;SLCO1A2;SLC18A2;SLC6A4 GO:0042220| response to cocaine OPRM1;SLC6A3;OPRK1 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0010033| response to organic substance UGT1A1;CREB1;SLC6A4 GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0007613| memory SLC6A4;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;SLC6A3 GO:0007568| aging SLC6A3;CREB1 GO:0006810| transport ABCB1;SLC6A2 GO:0042493| response to drug SLC6A4;CREB1;SLC6A2;UGT1A1;SLC6A3;ABCB1 GO:0007268| synaptic transmission SLC6A2;OPRK1;SLC18A2;OPRD1;OPRM1 GO:0007595| lactation CREB1;SLC6A3 GO:0035094| response to nicotine SLC6A3;CREB1 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0045471| response to ethanol SLC6A3;OPRK1;UGT1A1;OPRM1 GO:0007626| locomotory behavior OPRM1;SLC18A2;OPRK1;SLC6A3 9524:[DB01183 DB07354] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways GO:0007623| circadian rhythm CREB1;TOP1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;TOP1 GO:0016032| viral reproduction CREB1;TOP1 GO:0006338| chromatin remodeling TOP1;ESR1 GO:0048511| rhythmic process TOP1;CREB1 9525:[DB01183 DB14581] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14581|CPI-1205 EZH2 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;EZH2 GO:0048511| rhythmic process CREB1;EZH2 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity EZH2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter EZH2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter EZH2;ESR1 GO:0006351| transcription, DNA-dependent CREB1;EZH2;ESR1 GO:0042752| regulation of circadian rhythm CREB1;EZH2 GO:0071168| protein localization to chromatin ESR1;EZH2 GO:0010629| negative regulation of gene expression OPRD1;EZH2;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent EZH2;ESR1;CREB1 9526:[DB01183 DB04661] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways GO:0002376| immune system process TLR4;CD1D GO:0016032| viral reproduction CREB1;CD1D GO:0045087| innate immune response CD1D;TLR4 9527:[DB01183 DB02343] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways 9528:[DB01183 DB06990] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06990|4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID UNG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;UNG GO:0016032| viral reproduction CREB1;UNG 9529:[DB01183 DB08819] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0010628| positive regulation of gene expression PTGFR;TLR4 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0007165| signal transduction PTGFR;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0098869| PTGS2;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;PTGS2;OPRM1 GO:0007613| memory CREB1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007568| aging PTGS2;CREB1 GO:0032355| response to estradiol stimulus PTGFR;ESR1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PTGFR;OPRK1 GO:0006954| inflammatory response PTGS2;TLR4 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A4 GO:0042493| response to drug PTGS2;ABCB1;UGT1A1;CREB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGFR;PTGS2;ALB GO:0019233| sensory perception of pain OPRK1;PTGS2;OPRM1;OPRD1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;PTGFR;PTGS2;OPRM1 9530:[DB01183 DB00627] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0032094| response to food SLC16A1;OPRM1 GO:0042493| response to drug UGT1A1;CREB1;NNMT;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process SLC16A1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;SLCO2B1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006811| ion transport SLC22A5;SLCO1A2;SLCO2B1;SLC5A8 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport SLC16A3;SLC5A8;ABCB1;SLCO2B1;SLCO1A2;SLC22A5;SLC16A1 GO:0031100| organ regeneration UGT1A1;NNMT GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction HCAR2;OPRD1;OPRM1;ESR1;HCAR3;OPRK1;TLR4;CREB1 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0015711| organic anion transport SLC22A5;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO2B1;ALB GO:0008202| steroid metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway HCAR2;OPRM1;OPRD1;OPRK1;HCAR3 9531:[DB01183 DB00050] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GNRHR;OPRK1;LHCGR;OPRM1;OPRD1 GO:0007165| signal transduction OPRK1;GNRHR;TLR4;CREB1;OPRD1;OPRM1;ESR1;LHCGR GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;LHCGR GO:0008584| male gonad development LHCGR;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;LHCGR;OPRM1;OPRD1;OPRK1 9532:[DB01183 DB06732] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes ESR1 common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0006351| transcription, DNA-dependent AHR;CREB1;ESRRA;NR2F1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR2F1;ESRRA GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;CYP1A2;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;ESR1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR2F1;ESRRA GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRA;AHR;CREB1;TLR4;NR2F1;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;CYP1B1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0060065| uterus development ESR1 GO:0006805| xenobiotic metabolic process AHR;CYP2C8;CYP1B1;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1;CYP1A2 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP1B1;CYP3A4;CYP1A2 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR2F1;CREB1;AHR;ESRRA GO:0042493| response to drug CYP1A2;ABCB1;CREB1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESRRA;CREB1;AHR;ESR1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter ESRRA;ESR1;NR2F1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0032355| response to estradiol stimulus ESRRA;CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8;CYP1B1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;NR2F1;ESR1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C8;CYP1B1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0006366| transcription from RNA polymerase II promoter AHR;CREB1;ESR1 GO:0009636| response to toxin CES1;AHR;CYP1B1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0048511| rhythmic process CREB1;AHR GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0008285| negative regulation of cell proliferation CYP1B1;OPRM1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 9533:[DB01183 DB00341] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00341|Cetirizine HRH1 common genes common pathways GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HRH1;OPRD1;OPRK1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;HRH1;OPRM1;ESR1 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;HRH1;OPRK1 9534:[DB01183 DB05983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0050729| positive regulation of inflammatory response NFKBIA;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;NFKBIA GO:0034142| toll-like receptor 4 signaling pathway TLR4;NFKBIA GO:0016579| protein deubiquitination NFKBIA;ESR1 GO:0032496| response to lipopolysaccharide OPRM1;NFKBIA;UGT1A1;TLR4 GO:0000060| protein import into nucleus, translocation NFKBIA;OPRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;NFKBIA;ESR1 GO:0043066| negative regulation of apoptotic process ALB;NFKBIA GO:0031663| lipopolysaccharide-mediated signaling pathway NFKBIA;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NFKBIA;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;NFKBIA GO:0016032| viral reproduction NFKBIA;CREB1 9535:[DB01183 DB09336] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways GO:0048863| stem cell differentiation EPCAM;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;EPCAM;ESR1 9536:[DB01183 DB09532] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09532|Secretin human SCTR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;SCTR GO:0007165| signal transduction ESR1;OPRD1;OPRM1;SCTR;TLR4;CREB1;OPRK1 GO:0007586| digestion UGT1A1;SCTR 9537:[DB01183 DB04100] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0032496| response to lipopolysaccharide ABCC2;TLR4;UGT1A1;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;ABCC2;OPRK1 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0042493| response to drug CREB1;UGT1A1;ABCC2;ABCB1 GO:0006810| transport ABCB1;ABCC2 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCC2 GO:0043627| response to estrogen stimulus ESR1;OPRK1;ABCC2 9538:[DB01183 DB03041] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 9539:[DB01183 DB03556] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03556|2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 CBR1;CBR1 common genes common pathways GO:0017144| drug metabolic process CYP2C8;UGT1A1;CBR1;CYP3A4 GO:0030855| epithelial cell differentiation CBR1;CES1 GO:0055114| oxidation-reduction process CYP2C8;CBR1;CYP3A4 9540:[DB01183 DB00126] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity EGLN1;ESR1 GO:0008285| negative regulation of cell proliferation P3H1;P3H3;P3H2;OPRM1 GO:0001666| response to hypoxia EGLN2;EGLN1;EGLN3;PAM;CREB1;PLOD1;PLOD2 GO:0055085| transmembrane transport SLC23A1;ABCB1;SLCO1A2 GO:0009636| response to toxin SLC23A1;CES1 GO:0006811| ion transport SLCO1A2;SLC23A1 GO:0032870| cellular response to hormone stimulus UGT1A1;PLOD3 GO:0070989| oxidative demethylation CYP2C8;ALKBH2;CYP3A4 GO:0007613| memory DBH;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PAM GO:0032355| response to estradiol stimulus PAM;ESR1 GO:0050821| protein stabilization P3H1;CREB1 GO:0008542| visual learning DBH;CREB1 GO:0007595| lactation CREB1;PAM GO:0042711| maternal behavior DBH;OPRK1 GO:0055114| oxidation-reduction process PLOD3;DBH;ALKBH2;P3H3;ALKBH3;PLOD2;CYP3A4;TMLHE;KDM5D;P3H2;PLOD1;BBOX1;EGLN1;CYP2C8;EGLN3;OGFOD1;P3H1;P4HA1;EGLN2;OGFOD2;PHYH;P4HTM;PAM GO:0048149| behavioral response to ethanol DBH;OPRM1 GO:0042493| response to drug ABCB1;UGT1A1;PAM;CREB1 GO:0007268| synaptic transmission OPRK1;DBH;OPRM1;OPRD1 GO:0006355| regulation of transcription, DNA-dependent ESR1;KDM5D;CREB1 GO:0008152| metabolic process CES1;LCT;PAM;UGT1A1 GO:0007626| locomotory behavior OPRM1;DBH;OPRK1 GO:0030520| intracellular estrogen receptor signaling pathway EGLN2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGLN1;CREB1;TLR4;ESR1 GO:0006351| transcription, DNA-dependent ESR1;KDM5D;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PAM 9541:[DB01183 DB03442] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways GO:0008152| metabolic process CES1;ATIC;UGT1A1 GO:0031100| organ regeneration ATIC;UGT1A1 9542:[DB01183 DB09413] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09413|Monopotassium phosphate ALPI common genes common pathways GO:0008152| metabolic process UGT1A1;ALPI;CES1 GO:0007586| digestion ALPI;UGT1A1 9543:[DB01183 DB06360] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06360|Lucatumumab CD40 common genes common pathways GO:0051607| defense response to virus CD40;OPRK1 GO:0009617| response to bacterium CD40;TLR4 GO:0043491| protein kinase B signaling cascade CD40;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CD40;TLR4 GO:0006954| inflammatory response TLR4;CD40 GO:0006955| immune response OPRD1;OPRK1;TLR4;CD40 GO:0032496| response to lipopolysaccharide TLR4;CD40;UGT1A1;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;CD40 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CD40 GO:0071222| cellular response to lipopolysaccharide CD40;TLR4;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;CD40;ESR1 GO:0071260| cellular response to mechanical stimulus TLR4;CD40 GO:0030890| positive regulation of B cell proliferation CD40;TLR4 GO:0032735| positive regulation of interleukin-12 production TLR4;CD40 GO:0002376| immune system process TLR4;CD40 9544:[DB01183 DB07122] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07122|1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine PLAU common genes common pathways GO:0001666| response to hypoxia PLAU;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;PLAU;OPRK1 9545:[DB01183 DB02745] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;SLC29A1 GO:0007595| lactation CREB1;SLC29A1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1 9546:[DB01183 DB04059] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04059|8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0001666| response to hypoxia PLAU;CREB1 GO:0007165| signal transduction PLAU;OPRK1;CREB1;TLR4;ESR1;OPRM1;OPRD1 9547:[DB01183 DB11660] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11660|Latanoprostene Bunod PTGFR;SLCO2B1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGFR;ALB GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;PTGFR;OPRM1 GO:0010628| positive regulation of gene expression TLR4;PTGFR GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO2B1;ALB GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLCO1A2 GO:0006811| ion transport SLCO2B1;SLCO1A2 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;PTGFR GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO2B1;ALB GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PTGFR;OPRK1 GO:0032355| response to estradiol stimulus ESR1;PTGFR 9548:[DB01183 DB05017] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05017|YSIL6 TNF;IL6 common genes common pathways GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0043687| post-translational protein modification ALB;IL6 GO:0042742| defense response to bacterium TNF;TLR4 GO:0010629| negative regulation of gene expression TNF;CREB1;OPRD1;ESR1 GO:0051607| defense response to virus OPRK1;IL6 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;TNF;IL6 GO:0006953| acute-phase response IL6;UGT1A1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TLR4;IL6 GO:0006954| inflammatory response IL6;TNF;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;TNF;ESR1 GO:0006955| immune response OPRD1;OPRK1;IL6;TNF;TLR4 GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0050727| regulation of inflammatory response TLR4;TNF;ESR1 GO:0043065| positive regulation of apoptotic process TNF;CREB1;IL6 GO:0050829| defense response to Gram-negative bacterium IL6;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;TNF;OPRK1;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;TLR4;TNF;CREB1;ESR1 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TNF GO:0043066| negative regulation of apoptotic process ALB;IL6 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;TNF GO:0000187| activation of MAPK activity TNF;TLR4 GO:0044267| cellular protein metabolic process ALB;IL6 GO:0008285| negative regulation of cell proliferation IL6;OPRM1 GO:0010033| response to organic substance UGT1A1;TNF;CREB1 GO:0010628| positive regulation of gene expression IL6;TLR4;TNF GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF;IL6 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;IL6;OPRD1 GO:0032722| positive regulation of chemokine production TLR4;TNF;IL6 GO:0032757| positive regulation of interleukin-8 production TNF;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TNF;TLR4;IL6 GO:0032715| negative regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF 9549:[DB01183 DB03506] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03506|9-Deazaadenine APRT common genes common pathways GO:0007595| lactation CREB1;APRT 9550:[DB01183 DB03455] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways GO:0002376| immune system process IL2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration IL2;OPRM1;ESR1 GO:0050729| positive regulation of inflammatory response TLR4;IL2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;IL2;OPRK1 GO:0030890| positive regulation of B cell proliferation TLR4;IL2 GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;IL2 GO:0045471| response to ethanol UGT1A1;OPRK1;IL2;OPRM1 GO:0032729| positive regulation of interferon-gamma production IL2;TLR4 GO:0006955| immune response TLR4;OPRK1;IL2;OPRD1 9551:[DB01183 DB12119] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12119|Gevokizumab IL1B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;CREB1;TLR4;ESR1 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;IL1B GO:0031663| lipopolysaccharide-mediated signaling pathway IL1B;TLR4 GO:1900745| IL1B;OPRK1 GO:0071260| cellular response to mechanical stimulus IL1B;TLR4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;IL1B;OPRM1 GO:0032729| positive regulation of interferon-gamma production IL1B;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;IL1B GO:0046330| positive regulation of JNK cascade TLR4;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;TLR4 GO:0006954| inflammatory response IL1B;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;IL1B GO:0006955| immune response TLR4;OPRK1;IL1B;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;IL1B;CREB1 GO:0043491| protein kinase B signaling cascade CREB1;IL1B GO:0032757| positive regulation of interleukin-8 production TLR4;IL1B GO:0045429| positive regulation of nitric oxide biosynthetic process IL1B;TLR4;OPRM1;ESR1 GO:0032755| positive regulation of interleukin-6 production IL1B;TLR4 GO:0007165| signal transduction CREB1;TLR4;IL1B;OPRK1;ESR1;OPRM1;OPRD1 GO:0010628| positive regulation of gene expression IL1B;TLR4 GO:0008285| negative regulation of cell proliferation IL1B;OPRM1 GO:0000187| activation of MAPK activity IL1B;TLR4 9552:[DB01183 DB07617] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2A6;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2A6;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2A6 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2C8 9553:[DB01183 DB13751] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13751|Glycyrrhizic acid HSD11B1;TNF;CASP3;NFKB2;NFKB1;LPL;AKR1C4;AKR1C3;AKR1C2;ALB;ABCB11 common genes ALB common pathways GO:0050727| regulation of inflammatory response ESR1;TLR4;TNF GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0002576| platelet degranulation ALB GO:0043065| positive regulation of apoptotic process TNF;CREB1;CASP3 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;TNF;NFKB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;ESR1;TNF;TLR4;NFKB2;CREB1 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TNF GO:0043066| negative regulation of apoptotic process NFKB1;CASP3;ALB GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;ESR1;TNF;NFKB2 GO:0045087| innate immune response NFKB2;TLR4;NFKB1 GO:0006629| lipid metabolic process LPL;AKR1C2;HSD11B1;CYP3A4 GO:0071260| cellular response to mechanical stimulus NFKB1;TLR4 GO:0007586| digestion UGT1A1;AKR1C2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NFKB1 GO:0042060| wound healing CASP3;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;CASP3;TLR4;NFKB2;UGT1A1 GO:0032729| positive regulation of interferon-gamma production TNF;TLR4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0097190| apoptotic signaling pathway CASP3;TLR4;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1;AKR1C3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0006351| transcription, DNA-dependent NFKB2;CREB1;NFKB1;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;TLR4;NFKB2;TNF GO:0006954| inflammatory response TNF;NFKB2;TLR4;NFKB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;ESR1 GO:0006955| immune response OPRK1;TLR4;TNF;OPRD1 GO:0035094| response to nicotine CREB1;CASP3 GO:0010629| negative regulation of gene expression NFKB1;ESR1;OPRD1;TNF;CREB1 GO:0042493| response to drug ABCB1;LPL;CREB1;UGT1A1;CASP3 GO:0006355| regulation of transcription, DNA-dependent CREB1;NFKB2;NFKB1;ESR1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0045893| positive regulation of transcription, DNA-dependent CREB1;TNF;NFKB1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4;AKR1C4 GO:0043687| post-translational protein modification ALB GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0055114| oxidation-reduction process CYP3A4;AKR1C3;HSD11B1;AKR1C4;AKR1C2;CYP2C8 GO:0042742| defense response to bacterium TNF;TLR4 GO:0006898| receptor-mediated endocytosis ALB GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0098869| ALB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4;NFKB2;NFKB1 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0007165| signal transduction NFKB1;OPRD1;OPRM1;ESR1;OPRK1;NFKB2;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;TNF GO:0032722| positive regulation of chemokine production TNF;TLR4 GO:0032355| response to estradiol stimulus CASP3;ESR1 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1;CASP3 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;AKR1C3;OPRK1;AKR1C2 GO:0051659| maintenance of mitochondrion location ALB GO:0050729| positive regulation of inflammatory response LPL;TLR4 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation AKR1C3;ALB GO:0008202| steroid metabolic process UGT1A1;AKR1C4;AKR1C2;CYP2C8;AKR1C3;CYP3A4;HSD11B1 GO:0007568| aging NFKB2;CREB1 GO:0006810| transport ABCB1;ABCB11 GO:0043069| negative regulation of programmed cell death ALB GO:0008584| male gonad development AKR1C3;ESR1 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;ALB;AKR1C4 GO:0001666| response to hypoxia CREB1;CASP3 GO:0010628| positive regulation of gene expression TLR4;TNF GO:0048511| rhythmic process NFKB2;CREB1 GO:0007584| response to nutrient AKR1C3;UGT1A1 GO:0010033| response to organic substance CASP3;UGT1A1;CREB1;TNF GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound UGT1A1;CASP3 GO:0006366| transcription from RNA polymerase II promoter NFKB2;CREB1;ESR1;NFKB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;ABCB11 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;OPRM1 GO:0001895| retina homeostasis ALB GO:0000187| activation of MAPK activity TLR4;TNF GO:0030855| epithelial cell differentiation CES1;AKR1C2 GO:0044267| cellular protein metabolic process ALB 9554:[DB01183 DB02587] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes ABCB1 common pathways GO:0007165| signal transduction OPRK1;ADCY2;GNAS;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway ADCY5;OPRD1;OPRM1;OPRK1;GNAS;ADCY2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;ADCY5 GO:0042908| xenobiotic transport ABCB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY5;OPRD1;OPRM1;OPRK1;ADCY2 GO:0006810| transport ABCB1 GO:0016579| protein deubiquitination ESR1;CFTR GO:0006811| ion transport SLCO1A2;CFTR GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport CFTR;ABCB1;SLCO1A2 GO:0045672| positive regulation of osteoclast differentiation CREB1;GNAS GO:0007626| locomotory behavior OPRK1;OPRM1;ADCY5 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;ADCY5;GNAS GO:1901529| ABCB1 GO:0006695| cholesterol biosynthetic process CES1;CFTR GO:0042493| response to drug ABCB1;GNAS;UGT1A1;CREB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 9555:[DB01183 DB08049] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0042493| response to drug UGT1A1;COMT;CREB1;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;COMT;TLR4;OPRM1 GO:0043627| response to estrogen stimulus OPRK1;COMT;ESR1 GO:0051930| regulation of sensory perception of pain OPRK1;COMT;OPRM1;OPRD1 GO:0014070| response to organic cyclic compound UGT1A1;COMT 9556:[DB01183 DB11198] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 9557:[DB01183 DB03040] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03040|Nitrilotriacetic Acid LTF common genes common pathways GO:0002376| immune system process LTF;TLR4 GO:0006811| ion transport SLCO1A2;LTF GO:0044267| cellular protein metabolic process LTF;ALB GO:0001895| retina homeostasis ALB;LTF GO:0043066| negative regulation of apoptotic process ALB;LTF GO:0050829| defense response to Gram-negative bacterium TLR4;LTF GO:0045087| innate immune response LTF;TLR4 GO:0006351| transcription, DNA-dependent ESR1;LTF;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity LTF;TLR4 GO:0006355| regulation of transcription, DNA-dependent LTF;ESR1;CREB1 GO:0042742| defense response to bacterium TLR4;LTF 9558:[DB01183 DB00545] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00545|Pyridostigmine ACHE;BCHE;ALB;CYP3A4 common genes ALB;CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCB1;CREB1;BCHE;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0036378| CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0002933| CYP3A4;CYP2C8 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0007584| response to nutrient UGT1A1;BCHE GO:0009822| alkaloid catabolic process CYP3A4 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0042359| vitamin D metabolic process CYP3A4 9559:[DB01183 DB06549] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06549|Labradimil BDKRB2 common genes common pathways GO:0007165| signal transduction OPRM1;BDKRB2;OPRD1;ESR1;CREB1;TLR4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway BDKRB2;OPRD1;OPRM1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;BDKRB2;ESR1 GO:0006954| inflammatory response TLR4;BDKRB2 9560:[DB01183 DB12163] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12163|Sarpogrelate HTR2C;HTR2A common genes common pathways GO:0007268| synaptic transmission OPRK1;HTR2C;HTR2A;OPRD1;OPRM1 GO:0042493| response to drug HTR2A;HTR2C;ABCB1;CREB1;UGT1A1 GO:0016032| viral reproduction HTR2A;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2C;OPRK1;OPRM1;OPRD1;ESR1;HTR2A GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0007626| locomotory behavior OPRM1;HTR2C;OPRK1 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2C;TLR4;HTR2A;OPRM1 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2C;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR2C;OPRD1;OPRM1;HTR2A GO:0007613| memory HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007568| aging CREB1;HTR2A GO:0007610| behavior HTR2C;OPRK1;HTR2A GO:0007165| signal transduction HTR2C;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;HTR2A 9561:[DB01183 DB02405] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways 9562:[DB01183 DB07901] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07901|5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE METAP1 common genes common pathways 9563:[DB01183 DB08952] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08952|Indenolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 9564:[DB01183 DB09035] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09035|Nivolumab PDCD1 common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;PDCD1;OPRM1;TLR4;CREB1;OPRK1 GO:0002376| immune system process TLR4;PDCD1 GO:0043066| negative regulation of apoptotic process PDCD1;ALB GO:0043065| positive regulation of apoptotic process CREB1;PDCD1 9565:[DB01183 DB03028] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03028|1h-Benoximidazole-2-Carboxylic Acid CTSD common genes common pathways 9566:[DB01183 DB12159] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12159|Dupilumab IL4R common genes common pathways GO:0002376| immune system process IL4R;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;IL4R;OPRK1;TLR4;CREB1 GO:0043032| positive regulation of macrophage activation TLR4;IL4R GO:0043627| response to estrogen stimulus OPRK1;ESR1;IL4R GO:0006955| immune response IL4R;OPRD1;TLR4;OPRK1 9567:[DB01183 DB08770] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways GO:0007626| locomotory behavior OPRM1;ADORA2A;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA2A;OPRM1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0007600| sensory perception OPRK1;ADORA2A;OPRM1 GO:0006954| inflammatory response ADORA2A;TLR4 GO:0042493| response to drug ADORA2A;CREB1;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;CREB1;ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;TLR4;ADORA2A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADORA2A;OPRK1 GO:0008285| negative regulation of cell proliferation ADORA2A;OPRM1 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1 GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0042755| eating behavior OPRK1;ADORA2A;OPRD1;OPRM1 9568:[DB01183 DB01107] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRB3;GABRB1;GABRG2;GABRA4;GABRA6;GABRA1;ABCB1;GABRA5;GABRA3;GABRB2;GABRD GO:0007165| signal transduction OPRK1;GABRD;CREB1;TLR4;GABRP;GABRA5;GABRB3;ESR1;GABRA6;OPRM1;GABRE;GABRQ;OPRD1;GABRB1 GO:0006811| ion transport GABRB2;GABRD;GABRP;GABRG1;GABRA5;GABRA3;GABRA2;GABRA6;GABRA4;GABRA1;GABRE;SLCO1A2;GABRB1;GABRG2;GABRQ;GABRB3;GABRG3 GO:0009636| response to toxin GABRB1;CES1 GO:1901215| GABRB3;CREB1;GABRB2 GO:0007268| synaptic transmission GABRG2;OPRD1;OPRM1;OPRK1;GABRD;GABRB2;GABRA5;GABRG1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;GABRG3 9569:[DB01183 DB02900] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways GO:0001889| liver development UGT1A1;IGF2R GO:0042981| regulation of apoptotic process ESR1;IGF2R;CREB1 GO:0043065| positive regulation of apoptotic process CREB1;IGF2R GO:0007186| G-protein coupled receptor signaling pathway OPRK1;IGF2R;OPRM1;OPRD1 GO:0007165| signal transduction OPRD1;M6PR;OPRM1;ESR1;OPRK1;IGF2R;TLR4;CREB1 GO:0031100| organ regeneration UGT1A1;IGF2R GO:0006898| receptor-mediated endocytosis M6PR;ALB;IGF2R 9570:[DB01183 DB00424] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRM1;CHRM2;CHRM3;CREB1;TLR4;CHRM4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM2;CHRM1;CHRM3;CHRM4;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 9571:[DB01183 DB01946] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01946|3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione PDPK1;DMPK common genes common pathways GO:0006468| protein phosphorylation DMPK;CREB1;PDPK1 GO:0006351| transcription, DNA-dependent CREB1;PDPK1;ESR1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;CREB1;ESR1 9572:[DB01183 DB09535] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09535|Octocrylene ESR1;ESR2 common genes ESR1 common pathways GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;CREB1;TLR4;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1;ESR2 GO:0032355| response to estradiol stimulus ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 9573:[DB01183 DB04021] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04021|MF268 ACHE common genes common pathways 9574:[DB01183 DB09045] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09045|Dulaglutide GLP1R common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1;GLP1R GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;GLP1R;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;GLP1R 9575:[DB01183 DB06307] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06307|Apoptone BCL2 common genes common pathways GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0009314| response to radiation BCL2;OPRM1;OPRK1 GO:0042981| regulation of apoptotic process CREB1;BCL2;ESR1 GO:0035094| response to nicotine CREB1;BCL2 GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0042493| response to drug BCL2;ABCB1;CREB1;UGT1A1 GO:0051607| defense response to virus BCL2;OPRK1 GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BCL2 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2 GO:0040018| positive regulation of multicellular organism growth CREB1;BCL2 GO:0071456| cellular response to hypoxia OPRD1;BCL2 GO:0030890| positive regulation of B cell proliferation TLR4;BCL2 GO:0008584| male gonad development ESR1;BCL2 GO:0008285| negative regulation of cell proliferation OPRM1;BCL2 GO:0009636| response to toxin CES1;BCL2 GO:0007409| axonogenesis BCL2;CREB1 GO:0051881| regulation of mitochondrial membrane potential BCL2;OPRD1 GO:0055085| transmembrane transport ABCB1;BCL2;SLCO1A2 9576:[DB01183 DB09105] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09105|Asfotase Alfa S1PR1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;S1PR1;CREB1;ESR1 GO:0007165| signal transduction TLR4;S1PR1;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;S1PR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway S1PR1;OPRK1;OPRM1;OPRD1 9577:[DB01183 DB12130] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes CYP2C8 common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP3A5;CYP2C8;CYP2C19;CYP2B6 GO:0052695| cellular glucuronidation UGT1A1;UGT1A3 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP2B6;CYP3A4 GO:0051092| positive regulation of NF-kappaB transcription factor activity ALK;TLR4 GO:1904224| UGT1A3;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0042981| regulation of apoptotic process CREB1;ALK;ESR1 GO:0006082| organic acid metabolic process CYP2C8 GO:0008152| metabolic process CES1;UGT1A3;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C8;CYP2C19;CYP3A5;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2B6 GO:0000187| activation of MAPK activity ALK;TLR4 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0002933| CYP2C8;CYP3A5;CYP3A4 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A3 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0006468| protein phosphorylation CREB1;ALK GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;CYP2B6;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRM1;OPRD1;ALK;ESR1;CREB1;TLR4;OPRK1 GO:0017144| drug metabolic process UGT1A3;CYP3A4;CYP2C19;CYP2C8;CYP2B6;UGT1A1 GO:0097267| CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 9578:[DB01183 DB06325] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06325|Pegpleranib PDGFB common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;PDGFB GO:0048146| positive regulation of fibroblast proliferation ESR1;PDGFB GO:0010628| positive regulation of gene expression TLR4;PDGFB GO:0071363| cellular response to growth factor stimulus CREB1;PDGFB;OPRD1 GO:0006468| protein phosphorylation CREB1;PDGFB GO:0045893| positive regulation of transcription, DNA-dependent PDGFB;ESR1;CREB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;PDGFB;OPRD1 GO:0002576| platelet degranulation PDGFB;ALB 9579:[DB01183 DB07286] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07286|BMS-564929 AR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;AR GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;CREB1;TLR4 GO:0016579| protein deubiquitination AR;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression TLR4;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction ESR1;OPRD1;OPRM1;AR;TLR4;CREB1;OPRK1 9580:[DB01183 DB04620] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04620|Cycloleucine GRIN1 common genes common pathways GO:0043278| response to morphine OPRK1;OPRM1;GRIN1 GO:0008542| visual learning CREB1;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;TLR4;CREB1 GO:0043065| positive regulation of apoptotic process GRIN1;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN1;OPRM1 GO:0045471| response to ethanol OPRK1;UGT1A1;GRIN1;OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;GRIN1;OPRK1 GO:1903428| GRIN1;TLR4 GO:1904646| TLR4;GRIN1 GO:0008344| adult locomotory behavior OPRD1;GRIN1 GO:0006811| ion transport SLCO1A2;GRIN1 GO:0007613| memory CREB1;GRIN1 9581:[DB01183 DB07344] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways GO:0006629| lipid metabolic process CYP3A4;MCAT GO:0008152| metabolic process CES1;MCAT;UGT1A1 9582:[DB01183 DB03923] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03923|Feruloyl Coenzyme A COMTD1 common genes common pathways 9583:[DB01183 DB06688] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06688|Sipuleucel-T ACPP common genes common pathways GO:0051930| regulation of sensory perception of pain OPRK1;ACPP;OPRD1;OPRM1 9584:[DB01183 DB07394] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07394|AUROVERTIN B ATP5B common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ATP5B GO:0006811| ion transport SLCO1A2;ATP5B 9585:[DB01183 DB05192] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05192|MB07811 THRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;THRB GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;THRB GO:0060509| Type I pneumocyte differentiation CREB1;THRB GO:0043401| steroid hormone mediated signaling pathway ESR1;THRB GO:0006351| transcription, DNA-dependent THRB;CREB1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;THRB;ESR1 9586:[DB01183 DB04519] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0015711| organic anion transport SLC22A6;SLCO1A2;SLC22A11 GO:0043252| sodium-independent organic anion transport SLC22A11;SLCO1A2;SLC22A8;ALB;SLC22A6 GO:0001666| response to hypoxia CREB1;PPARA GO:0048511| rhythmic process PPARA;CREB1 GO:0006811| ion transport SLC22A11;SLCO1A2;SLC22A8 GO:0009636| response to toxin CES1;SLC22A8 GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0055085| transmembrane transport SLC22A6;ABCB1;SLCO1A2;SLC22A8;SLC22A11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARA;TLR4;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA GO:0006629| lipid metabolic process PPARA;CYP3A4 GO:0042060| wound healing PPARA;OPRM1 GO:0043401| steroid hormone mediated signaling pathway PPARA;ESR1 GO:0006351| transcription, DNA-dependent CREB1;PPARA;ESR1 GO:0042752| regulation of circadian rhythm PPARA;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARA;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARA;ESR1 GO:1901215| CREB1;PPARA 9587:[DB01183 DB03664] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03664|UP5 CMPK1 common genes common pathways 9588:[DB01183 DB08088] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development ESR1;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction AR;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;AR;ESR1 9589:[DB01183 DB08740] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08740|CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE CTSD common genes common pathways 9590:[DB01183 DB00191] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0009636| response to toxin MAOB;CES1;SLC6A4 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;SLC6A3 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLCO1A2;SLC6A4 GO:0042220| response to cocaine OPRK1;SLC6A3;OPRM1 GO:0001666| response to hypoxia CREB1;SLC6A4 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2;SLC6A4 GO:0032355| response to estradiol stimulus SLC6A4;ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0007613| memory SLC6A4;CREB1 GO:0006810| transport ABCB1;SLC6A2 GO:0007568| aging SLC6A3;CREB1 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0007268| synaptic transmission OPRK1;SLC6A2;OPRD1;OPRM1 GO:0042493| response to drug CYP1A2;SLC6A4;SLC6A2;MAOB;UGT1A1;CREB1;ABCB1;SLC6A3 GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP1A2;CYP2C8;MAOB GO:0007595| lactation SLC6A3;CREB1 GO:0035094| response to nicotine SLC6A3;CREB1 GO:0032496| response to lipopolysaccharide TLR4;MAOB;UGT1A1;OPRM1;CYP1A2 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0045471| response to ethanol SLC6A3;OPRK1;UGT1A1;MAOB;OPRM1 GO:0007626| locomotory behavior OPRK1;SLC6A3;OPRM1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 9591:[DB01183 DB06650] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06650|Ofatumumab MS4A1 common genes common pathways 9592:[DB01183 DB00371] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0007268| synaptic transmission GABRG1;GABRA5;GABRB2;GABRD;OPRK1;OPRM1;GABRG2;OPRD1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP2E1;GABRG3 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2E1;CYP3A4 GO:1901215| GABRB3;GABRB2;CREB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0045471| response to ethanol UGT1A1;OPRK1;CYP2E1;OPRM1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CES1;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0006811| ion transport GABRA2;GABRG1;GABRA5;GABRA3;GABRB2;GABRD;GABRP;GABRB3;GABRG3;GABRE;SLCO1A2;GABRG2;GABRB1;GABRQ;GABRA4;GABRA6;GABRA1 GO:0009636| response to toxin GABRB1;CES1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 GO:0006810| transport GABRA1;GABRA6;GABRA4;GABRG2;GABRB1;GABRB3;GABRB2;GABRD;GABRA3;GABRA5;ABCB1 GO:0007165| signal transduction GABRB3;ESR1;GABRA6;GABRE;OPRM1;GABRQ;GABRB1;OPRD1;OPRK1;GABRD;CREB1;TLR4;GABRP;GABRA5 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0097267| CYP2C19;CYP2C8 9593:[DB01183 DB03456] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03456|N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 9594:[DB01183 DB04409] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways GO:0000187| activation of MAPK activity FGF1;TLR4 GO:0030154| cell differentiation FGF1;CREB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;FGF1;ESR1;OPRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;FGF1;TLR4;CREB1 9595:[DB01183 DB08560] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;CREB1;PPARG GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;PPARG;CREB1;ESR1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response PPARG;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;PPARG;TLR4;OPRK1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance PPARG;CREB1;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0048511| rhythmic process PPARG;CREB1 GO:0007584| response to nutrient PPARG;UGT1A1 9596:[DB01183 DB07917] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways GO:0007165| signal transduction HPGDS;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0006629| lipid metabolic process HPGDS;CYP3A4 GO:0007626| locomotory behavior OPRK1;HPGDS;OPRM1 9597:[DB01183 DB03384] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03384|Fica CASP7 common genes common pathways 9598:[DB01183 DB07630] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07630|N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways 9599:[DB01183 DB00283] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00283|Clemastine HRH1;CYP2D6 common genes common pathways GO:0007613| memory HRH1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;HRH1;OPRK1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;HRH1;OPRD1;OPRK1;CREB1;TLR4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;HRH1;OPRK1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 9600:[DB01183 DB00931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00931|Metacycline ALB common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043069| negative regulation of programmed cell death ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB 9601:[DB01183 DB05233] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05233|AP1081 ESR1 common genes ESR1 common pathways GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;OPRK1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 9602:[DB01183 DB07789] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0006468| protein phosphorylation CREB1;PLK1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;ESR1 GO:0043066| negative regulation of apoptotic process PLK1;ALB GO:0071168| protein localization to chromatin PLK1;ESR1 9603:[DB01183 DB06945] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways GO:0042742| defense response to bacterium ADAMTS5;TLR4 9604:[DB01183 DB00856] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00856|Chlorphenesin CYP2B;CYP19A1;CYP3A4;XDH;PTGS2;BCHE common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0002933| CYP3A4;CYP2C8 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0010033| response to organic substance PTGS2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation BCHE;PTGS2;OPRM1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0007568| aging PTGS2;CREB1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory CREB1;PTGS2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0098869| ALB;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;PTGS2;ESR1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process PTGS2;XDH;CYP3A4;CYP19A1;CYP2C8 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;XDH;OPRD1;CREB1 GO:0042493| response to drug BCHE;UGT1A1;CREB1;ABCB1;PTGS2 GO:0007595| lactation XDH;CREB1 GO:0006954| inflammatory response PTGS2;TLR4 GO:0019233| sensory perception of pain OPRK1;OPRM1;PTGS2;OPRD1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:1900745| XDH;OPRK1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0060065| uterus development CYP19A1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0050727| regulation of inflammatory response TLR4;ESR1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 9605:[DB01183 DB02328] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02328|2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid CTH common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CTH GO:0051092| positive regulation of NF-kappaB transcription factor activity CTH;TLR4 GO:1990830| CTH;CREB1 9606:[DB01183 DB04491] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04491|Diisopropylphosphono Group CFB;DPP4 common genes common pathways GO:0045087| innate immune response CFB;TLR4 GO:0001666| response to hypoxia CREB1;DPP4 GO:0002376| immune system process TLR4;CFB 9607:[DB01183 DB01089] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01089|Deserpidine SLC18A2 common genes common pathways GO:0007626| locomotory behavior OPRK1;OPRM1;SLC18A2 GO:0007268| synaptic transmission OPRK1;SLC18A2;OPRM1;OPRD1 GO:0055085| transmembrane transport ABCB1;SLC18A2;SLCO1A2 GO:0009636| response to toxin SLC18A2;CES1 9608:[DB01183 DB13166] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13166|Zofenopril ACE common genes common pathways 9609:[DB01183 DB00108] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0007165| signal transduction OPRD1;FCGR2C;OPRM1;ESR1;FCGR1A;OPRK1;TLR4;CREB1;FCGR2B GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB GO:0002376| immune system process TLR4;C1QB;C1R;FCGR1A;FCGR2A;C1QC;C1QA GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;ICAM1 GO:0071456| cellular response to hypoxia OPRD1;ICAM1 GO:1990830| ICAM1;CREB1 GO:0001666| response to hypoxia CREB1;ICAM1 GO:1904646| FCGR2B;TLR4 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ICAM1 GO:0032868| response to insulin stimulus ICAM1;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;ICAM1 GO:0014070| response to organic cyclic compound ICAM1;UGT1A1 GO:0045087| innate immune response C1QA;C1QC;FCGR1A;C1R;C1QB;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;ICAM1;TLR4 GO:0045471| response to ethanol ICAM1;UGT1A1;OPRK1;OPRM1 GO:0046330| positive regulation of JNK cascade TLR4;FCGR2B GO:0032496| response to lipopolysaccharide TLR4;ICAM1;UGT1A1;OPRM1 GO:0051092| positive regulation of NF-kappaB transcription factor activity ICAM1;TLR4 GO:0006954| inflammatory response FCGR2B;TLR4 GO:0006955| immune response FCGR3A;FCGR2C;OPRD1;C1QC;C1R;TLR4;FCGR3B;FCGR2B;OPRK1;FCGR1A GO:0016032| viral reproduction ICAM1;FCGR2B;CREB1 GO:0009617| response to bacterium FCGR2B;TLR4 GO:0042493| response to drug CREB1;ICAM1;UGT1A1;ABCB1 9610:[DB01183 DB08930] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes UGT1A1;ABCB1;CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0031100| organ regeneration UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0015711| organic anion transport SLCO1A2;SLC22A6;SLC22A2 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2C8;CYP3A4;UGT1A3 GO:0072089| stem cell proliferation ABCB1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP2C8;CYP3A5;UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A8;SLCO1A2 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006810| transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0007584| response to nutrient UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1;UGT1A3 GO:0010033| response to organic substance CREB1;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9;UGT1A3 GO:0006811| ion transport SLC22A8;SLCO1A2;SLC22A2 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A9;UGT1A1 GO:0009636| response to toxin SLC22A8;CES1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9;UGT1A3 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0055085| transmembrane transport SLC22A6;ABCB1;ABCG2;SLC22A2;SLCO1A2;SLC22A8 GO:0036378| CYP3A4 GO:0006855| drug transmembrane transport SLC22A2;ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;UGT1A9;CYP3A7;CES1;CYP3A4 GO:0008152| metabolic process UGT1A3;CES1;UGT1A9;UGT1A1 GO:0007586| digestion UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0071361| cellular response to ethanol UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:1904224| UGT1A1;UGT1A9;UGT1A3 GO:0070980| biphenyl catabolic process UGT1A1 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1 GO:0001889| liver development UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1;UGT1A9 GO:0006789| bilirubin conjugation UGT1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;CYP3A43;CYP3A5;CYP2C8 GO:0099040| ABCB1 GO:0052695| cellular glucuronidation UGT1A3;UGT1A9;UGT1A1 9611:[DB01183 DB11858] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CYSLTR2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration CYSLTR1;ESR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway CYSLTR2;OPRD1;OPRM1;OPRK1;CYSLTR1 GO:0007165| signal transduction CYSLTR1;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1;CYSLTR2 GO:0006955| immune response OPRD1;CYSLTR2;OPRK1;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;CYSLTR1;CYSLTR2;ESR1;OPRM1;OPRD1 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;CYSLTR2;CYSLTR1;OPRK1 9612:[DB01183 DB14132] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0006954| inflammatory response ADORA2A;TLR4 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0007600| sensory perception OPRM1;OPRK1;ADORA2A GO:0006355| regulation of transcription, DNA-dependent CREB1;ADORA2A;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ADORA2A;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0007626| locomotory behavior OPRM1;OPRK1;ADORA2A GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;ADORA2A GO:0008285| negative regulation of cell proliferation OPRM1;ADORA2A GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1;ADORA2A GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1 GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;ADORA2A;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;ADORA2A GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 9613:[DB01183 DB09070] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes ESR1 common pathways GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0008152| metabolic process HSD3B1;UGT1A1;CES1;HSD3B2;STS GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;SULT1A1 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0006629| lipid metabolic process STS;CYP3A4;SULT1A1 GO:0006706| steroid catabolic process STS;CYP3A4 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0043687| post-translational protein modification STS;ALB GO:0055114| oxidation-reduction process CYP3A4;HSD3B2;CYP2C8;HSD3B1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0008210| estrogen metabolic process SULT1A1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0008202| steroid metabolic process UGT1A1;SULT1A1;CYP2C8;STS;CYP3A4 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0002064| epithelial cell development ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 9614:[DB01183 DB09479] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09479|Rubidium Rb-82 FXYD2;ATP1A1;ATP1B1;ATP1B2;ATP1B3;ATP1A4;ATP1A2;ATP1A3 common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4;ATP1A2 GO:0051481| reduction of cytosolic calcium ion concentration ATP1A2;OPRM1 GO:0035094| response to nicotine CREB1;ATP1A2 GO:0008542| visual learning CREB1;ATP1A3;ATP1A2 GO:0042493| response to drug ATP1A1;ABCB1;UGT1A1;CREB1;ATP1A3 GO:0006810| transport ATP1B2;ABCB1;ATP1B3;FXYD2 GO:0007613| memory ATP1A3;CREB1 GO:0050821| protein stabilization ATP1B2;ATP1B3;CREB1;ATP1B1 GO:1904646| TLR4;ATP1A3 GO:0001666| response to hypoxia CREB1;ATP1B1 GO:0008344| adult locomotory behavior OPRD1;ATP1A2;ATP1A3 GO:0006811| ion transport FXYD2;ATP1A3;ATP1B1;ATP1A2;ATP1B3;ATP1A1;SLCO1A2;ATP1A4;ATP1B2 9615:[DB01183 DB02462] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02462|Thiocoumarin NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0010629| negative regulation of gene expression OPRD1;ESR1;NOS2;CREB1 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process NOS2;CYP2C8;CYP3A4 GO:0009617| response to bacterium NOS2;TLR4 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 GO:0032496| response to lipopolysaccharide OPRM1;NOS2;TLR4;UGT1A1 GO:0007623| circadian rhythm CREB1;NOS2 9616:[DB01183 DB02395] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02395|3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol NQO1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;NQO1 GO:0006805| xenobiotic metabolic process CYP2C8;NQO1;CYP3A4;CES1 GO:0045471| response to ethanol OPRK1;UGT1A1;NQO1;OPRM1 GO:0055114| oxidation-reduction process CYP2C8;NQO1;CYP3A4 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 GO:0007568| aging NQO1;CREB1 GO:0032355| response to estradiol stimulus ESR1;NQO1 GO:0007584| response to nutrient UGT1A1;NQO1 GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0009636| response to toxin CES1;NQO1 9617:[DB01183 DB00964] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;OPRD1;OPRM1;ESR1 GO:0042493| response to drug ADRA1A;ABCB1;CREB1;UGT1A1 GO:0007165| signal transduction CREB1;TLR4;ADRA1A;ADRA2A;OPRK1;OPRM1;OPRD1;ESR1;ADRA2B GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1 GO:0007568| aging ADRA1A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;OPRK1;ADRA1A;ADRA2B;OPRM1;OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;ADRA1A GO:0000187| activation of MAPK activity TLR4;ADRA2B 9618:[DB01183 DB00487] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TOP2A;TLR4 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0048511| rhythmic process TOP2A;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 9619:[DB01183 DB07154] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9620:[DB01183 DB13881] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13881|Tisagenlecleucel CD19 common genes common pathways 9621:[DB01183 DB03703] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03703|Cyclohexanol ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;CYP2C8;CYP3A4 9622:[DB01183 DB09203] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09203|Synephrine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ADRA1A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;ESR1;OPRD1;OPRM1;OPRK1;ADRA1A;ADRA1D GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;OPRM1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0007568| aging ADRA1A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ESR1;OPRM1;ADRA1B GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;ADRA1A;OPRK1;OPRM1;OPRD1;ADRA1B GO:0007165| signal transduction ESR1;OPRD1;OPRM1;ADRA1B;TLR4;CREB1;ADRA1D;OPRK1;ADRA1A 9623:[DB01183 DB13132] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13132|Artemisinin CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2B6;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2B6 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2B6;CYP2C8 9624:[DB01183 DB04852] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04852|Implitapide MTTP common genes common pathways GO:0006629| lipid metabolic process CYP3A4;MTTP 9625:[DB01183 DB05920] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05920|RTA 744 TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TOP2A;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0048511| rhythmic process TOP2A;CREB1 9626:[DB01183 DB03894] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03894|N-Propargyl-1(S)-Aminoindan MAOB;MAOB common genes common pathways GO:0042493| response to drug MAOB;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MAOB;OPRM1 GO:0045471| response to ethanol UGT1A1;MAOB;OPRK1;OPRM1 GO:0009636| response to toxin CES1;MAOB GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 9627:[DB01183 DB05938] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05938|Edonerpic APP common genes common pathways GO:1904646| TLR4;APP GO:0010628| positive regulation of gene expression APP;TLR4 GO:0008285| negative regulation of cell proliferation APP;OPRM1 GO:1903223| TLR4;APP GO:0007409| axonogenesis CREB1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;APP;TLR4 GO:0000187| activation of MAPK activity TLR4;APP GO:0008344| adult locomotory behavior OPRD1;APP GO:0044267| cellular protein metabolic process APP;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TLR4;OPRM1;ESR1 GO:1900273| CREB1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;APP;OPRK1 GO:0007613| memory APP;CREB1 GO:0006468| protein phosphorylation APP;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;APP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;APP GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;ESR1 GO:0008542| visual learning CREB1;APP GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;APP GO:0010629| negative regulation of gene expression CREB1;APP;ESR1;OPRD1 GO:1901215| CREB1;APP GO:0043687| post-translational protein modification APP;ALB GO:0002576| platelet degranulation APP;ALB GO:0043065| positive regulation of apoptotic process APP;CREB1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0007626| locomotory behavior OPRM1;OPRK1;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;APP;ESR1 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;APP GO:1990090| CREB1;APP GO:0045087| innate immune response APP;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;ESR1 GO:0046330| positive regulation of JNK cascade TLR4;APP 9628:[DB01183 DB12610] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12610|Ebselen EPHX2 common genes common pathways GO:0006954| inflammatory response EPHX2;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;EPHX2 GO:0008152| metabolic process CES1;EPHX2;UGT1A1 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0009636| response to toxin CES1;EPHX2 GO:0010628| positive regulation of gene expression TLR4;EPHX2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;EPHX2;CYP3A4 9629:[DB01183 DB11397] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11397|Dichlorvos TF;BCHE;ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation TF;ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB;TF GO:0042493| response to drug CREB1;BCHE;UGT1A1;ABCB1 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0051659| maintenance of mitochondrion location ALB GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0044267| cellular protein metabolic process ALB;TF GO:0001895| retina homeostasis ALB;TF GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport TF;SLCO1A2 9630:[DB01183 DB00600] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00600|Monobenzone TYR common genes common pathways GO:0008152| metabolic process TYR;CES1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;TYR 9631:[DB01183 DB03889] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 9632:[DB01183 DB01831] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways GO:0010628| positive regulation of gene expression TLR4;WARS GO:0008285| negative regulation of cell proliferation WARS;OPRM1 9633:[DB01183 DB02637] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02637|Oxaloacetate Ion CS;mdh;SPR common genes common pathways GO:0055114| oxidation-reduction process SPR;CYP3A4;CYP2C8 9634:[DB01183 DB08435] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0045087| innate immune response PPARG;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CREB1;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0042493| response to drug ABCB1;UGT1A1;PPARG;CREB1 GO:0007165| signal transduction PPARG;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0048511| rhythmic process CREB1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG 9635:[DB01183 DB07580] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07580|BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE APCS common genes common pathways GO:0044267| cellular protein metabolic process ALB;APCS GO:0006953| acute-phase response UGT1A1;APCS GO:0045087| innate immune response TLR4;APCS 9636:[DB01183 DB00104] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes CYP3A4 common pathways GO:0006629| lipid metabolic process CYP3A4 GO:0042594| response to starvation SSTR1;SSTR2;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0007586| digestion SSTR1;UGT1A1;SSTR2 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1;SSTR1;SSTR2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide MPO;OPRM1;TLR4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus SSTR5;SSTR2;UGT1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;MPO;CYP2C8 GO:0042742| defense response to bacterium TLR4;MPO GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0007268| synaptic transmission OPRK1;SSTR5;OPRD1;OPRM1 GO:0032094| response to food MPO;OPRM1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0007165| signal transduction SSTR1;CREB1;TLR4;SSTR2;OPRK1;ESR1;OPRM1;OPRD1;SSTR5 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0071392| cellular response to estradiol stimulus ESR1;SSTR2;UGT1A1;SSTR1 GO:0007568| aging CREB1;MPO GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;SSTR2;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;SSTR2;SSTR1;SSTR5;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger SSTR5;OPRD1;OPRM1;SSTR2;SSTR1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007584| response to nutrient SSTR1;SSTR2;UGT1A1 GO:0008285| negative regulation of cell proliferation SSTR5;OPRM1;SSTR1;SSTR2 GO:1990830| SSTR1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 9637:[DB01183 DB06410] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;VDR GO:0006367| transcription initiation from RNA polymerase II promoter VDR;ESR1 GO:0007595| lactation CREB1;VDR GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;VDR GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP27A1;CYP2C8 GO:0007165| signal transduction VDR;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0010628| positive regulation of gene expression VDR;TLR4 GO:0008285| negative regulation of cell proliferation VDR;OPRM1 9638:[DB01183 DB01064] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 GO:0007165| signal transduction OPRD1;OPRM1;ADRB2;ESR1;ADRB1;OPRK1;ADRB3;PIK3R1;MAPK1;PIK3R2;TLR4;CREB1 GO:0097267| CYP1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A1;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP1A1;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRB2;ADRB1;PIK3R1;ADRB3;OPRK1 GO:0050821| protein stabilization PIK3R1;CREB1 GO:0007568| aging ADRB3;CREB1;CYP1A1;SOD1 GO:0006468| protein phosphorylation PIK3R1;CREB1;MAPK1 GO:0010628| positive regulation of gene expression MAPK1;TLR4 GO:1904646| ADRB2;TLR4 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0010033| response to organic substance SOD1;UGT1A1;CREB1;CYP1A1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;MAPK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;ADRB3 GO:0007411| axon guidance PIK3R1;CREB1;MAPK1 GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0009636| response to toxin CYP1A1;MAPK1;CES1 GO:0042755| eating behavior OPRD1;OPRM1;ADRB3;OPRK1 GO:0000187| activation of MAPK activity MAPK1;TLR4;SOD1 GO:0001895| retina homeostasis SOD1;ALB GO:0045671| negative regulation of osteoclast differentiation TLR4;PIK3R1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0043066| negative regulation of apoptotic process PIK3R1;ALB;SOD1 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;MAPK1 GO:0043065| positive regulation of apoptotic process CREB1;SOD1 GO:0002576| platelet degranulation ALB;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PIK3R1;TLR4;CREB1;PIK3R2;ADRB2;ESR1 GO:0007626| locomotory behavior OPRM1;SOD1;OPRK1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide MAPK1;UGT1A1;TLR4;CYP1A1;OPRM1 GO:0006351| transcription, DNA-dependent MAPK1;CREB1;ESR1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0019233| sensory perception of pain MAPK1;OPRK1;OPRM1;OPRD1 GO:0045471| response to ethanol OPRK1;UGT1A1;SOD1;OPRM1 GO:0016032| viral reproduction PIK3R1;MAPK1;CREB1 GO:0035094| response to nicotine MAPK1;CREB1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;PIK3R1 GO:0032094| response to food OPRM1;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent MAPK1;CREB1;ESR1 GO:0042493| response to drug UGT1A1;CREB1;CYP1A1;ABCB1;SOD1 GO:0007268| synaptic transmission OPRM1;OPRD1;MAPK1;OPRK1 GO:0006355| regulation of transcription, DNA-dependent MAPK1;CREB1;ESR1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C8;CYP3A4;SOD1 9639:[DB01183 DB03948] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03948|6-Chloropurine Riboside, 5'-Monophosphate IMPDH1;IMPDH2 common genes common pathways GO:0007623| circadian rhythm CREB1;IMPDH2 GO:0055114| oxidation-reduction process IMPDH1;CYP2C8;IMPDH2;CYP3A4 9640:[DB01183 DB06721] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06721|Gimatecan SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLCO1B1;ABCB1 GO:0006811| ion transport SLCO1A2;SLCO1B1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1 GO:0015711| organic anion transport SLCO1A2;SLCO1B1 9641:[DB01183 DB04853] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04853|Binodenoson ADORA2A common genes common pathways GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0051881| regulation of mitochondrial membrane potential OPRD1;ADORA2A GO:0042755| eating behavior ADORA2A;OPRK1;OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;ADORA2A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;ADORA2A GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ADORA2A;CREB1;ESR1 GO:0042493| response to drug UGT1A1;CREB1;ADORA2A;ABCB1 GO:0007600| sensory perception OPRM1;ADORA2A;OPRK1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0006954| inflammatory response TLR4;ADORA2A GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;ADORA2A GO:0007626| locomotory behavior OPRM1;OPRK1;ADORA2A 9642:[DB01183 DB02515] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways GO:0042594| response to starvation PFKFB1;UGT1A1 GO:0033762| response to glucagon stimulus CREB1;PFKFB1 GO:0008152| metabolic process PFKFB1;CES1;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PFKFB1 GO:0031100| organ regeneration PFKFB1;UGT1A1 GO:0032868| response to insulin stimulus PFKFB1;OPRK1 9643:[DB01183 DB03486] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CANT1;CREB1;TLR4;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CANT1 9644:[DB01183 DB07747] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07747|(3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 9645:[DB01183 DB10772] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways GO:0000060| protein import into nucleus, translocation OPRD1;TGFB1;IFNG;TNF GO:0045471| response to ethanol FGFR2;OPRM1;OPRK1;UGT1A1 GO:0097190| apoptotic signaling pathway TNF;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4;IL1B GO:0046330| positive regulation of JNK cascade TNF;TLR4;IL1B GO:0001889| liver development UGT1A1;EGFR GO:0042060| wound healing EGFR;PDGFRA;TGFBR2;TGFB1;OPRM1;FGFR2 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1;FGFR2 GO:0007623| circadian rhythm CREB1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA;EGFR GO:0032496| response to lipopolysaccharide FGFR2;OPRM1;IL1B;UGT1A1;TLR4 GO:0032729| positive regulation of interferon-gamma production IL1B;TLR4;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;TGFB1;VEGFA;ESR1;IFNG;FGFR2 GO:0042981| regulation of apoptotic process CREB1;TGFB1;ESR1 GO:0060749| mammary gland alveolus development VEGFA;ESR1 GO:1900745| VEGFA;IL1B;OPRK1 GO:0071260| cellular response to mechanical stimulus TLR4;EGFR;IL1B;TGFB1 GO:0002576| platelet degranulation TGFB1;VEGFA;ALB GO:0043065| positive regulation of apoptotic process TGFB1;CREB1;TNF;IL6 GO:0050727| regulation of inflammatory response ESR1;TNF;TLR4 GO:0045672| positive regulation of osteoclast differentiation IFNG;TNF;CREB1 GO:0009314| response to radiation TGFB1;OPRM1;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IL6;IL1B;TLR4;TNF;CREB1;FGFR2;TGFB1;VEGFA;FGF1;ESR1 GO:0050829| defense response to Gram-negative bacterium IL6;TLR4 GO:0071222| cellular response to lipopolysaccharide IL6;OPRK1;TLR4;TNF GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TNF;IL1B GO:0031663| lipopolysaccharide-mediated signaling pathway TGFB1;IL1B;TLR4;TNF GO:0043066| negative regulation of apoptotic process EGFR;IL6;ALB;VEGFA GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;FGFR2;TGFB1 GO:0042742| defense response to bacterium TNF;TLR4 GO:0043687| post-translational protein modification ALB;IL6 GO:0043491| protein kinase B signaling cascade TNF;CREB1;IL1B;TGFB1 GO:0042493| response to drug TGFB1;TGFBR2;UGT1A1;CREB1;ABCB1 GO:0010629| negative regulation of gene expression ESR1;VEGFA;OPRD1;TGFB1;IFNG;CREB1;TNF GO:0051607| defense response to virus IL6;OPRK1;IFNG GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent TNF;CREB1;IL1B;IL6;EGFR;ESR1;TGFB1 GO:0006953| acute-phase response IL6;UGT1A1 GO:0007595| lactation CREB1;VEGFA GO:0060687| regulation of branching involved in prostate gland morphogenesis FGFR2;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;IL6;TNF;TLR4;TGFB1 GO:0006954| inflammatory response TGFB1;TNF;TLR4;IL1B;IL6 GO:0006955| immune response IL6;OPRK1;IL1B;TLR4;TNF;IFNG;OPRD1 GO:0016032| viral reproduction PDGFRA;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;IL1B;IL6;ESR1 GO:0030154| cell differentiation CREB1;TGFBR2;FGF1;VEGFA GO:0006468| protein phosphorylation PDGFRA;EGFR;CREB1;FGFR2;TGFB1;TGFBR2 GO:0071392| cellular response to estradiol stimulus ESR1;EGFR;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration PDGFRA;OPRM1;ESR1 GO:0071456| cellular response to hypoxia VEGFA;OPRD1 GO:0032700| negative regulation of interleukin-17 production IFNG;TGFB1;TLR4 GO:0007568| aging TGFBR2;TGFB1;CREB1 GO:1990314| TGFB1;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF;IL6 GO:0032735| positive regulation of interleukin-12 production TLR4;IFNG GO:0032355| response to estradiol stimulus ESR1;TGFB1;EGFR GO:0071363| cellular response to growth factor stimulus OPRD1;TGFB1;CREB1;EGFR GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0007165| signal transduction TLR4;CREB1;OPRK1;IL1B;EGFR;ESR1;FGF1;OPRD1;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;EGFR;IL6;VEGFA;OPRD1;TGFB1 GO:0048545| response to steroid hormone stimulus TGFBR2;UGT1A1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0032722| positive regulation of chemokine production TLR4;TNF;IL6 GO:0031100| organ regeneration UGT1A1;TGFB1;TGFBR2 GO:0006898| receptor-mediated endocytosis ALB;TGFBR2 GO:0032757| positive regulation of interleukin-8 production TLR4;TNF;IL1B GO:1903799| TGFB1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1;PDGFRA GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;IL1B;TLR4;TNF;IFNG;OPRM1;ESR1 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production IL1B;IL6;TLR4;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;EGFR;PDGFRA;OPRM1;VEGFA;TGFB1;FGFR2 GO:0000187| activation of MAPK activity TNF;TLR4;IL1B;FGF1 GO:0030855| epithelial cell differentiation FGFR2;CES1;VEGFA GO:0044267| cellular protein metabolic process IL6;ALB;CSF2RA GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;TGFB1;TGFBR2 GO:0007409| axonogenesis FGFR2;CREB1 GO:0030879| mammary gland development TGFB1;CREB1 GO:0014070| response to organic cyclic compound TGFBR2;TGFB1;EGFR;UGT1A1 GO:0043627| response to estrogen stimulus OPRK1;TGFBR2;ESR1 GO:0007584| response to nutrient TGFBR2;UGT1A1 GO:0010033| response to organic substance CREB1;TNF;UGT1A1;TGFBR2;TGFB1 GO:0008285| negative regulation of cell proliferation TGFBR2;TGFB1;OPRM1;IL1B;IL6 GO:0010628| positive regulation of gene expression TGFB1;VEGFA;IFNG;TNF;TLR4;IL1B;IL6 GO:0001666| response to hypoxia TGFBR2;VEGFA;TGFB1;CREB1 GO:0060523| prostate epithelial cord elongation ESR1;FGFR2 GO:0048146| positive regulation of fibroblast proliferation TGFB1;ESR1;EGFR;PDGFRA 9646:[DB01183 DB02107] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 9647:[DB01183 DB08488] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08488|4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE F10 common genes common pathways 9648:[DB01183 DB07087] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07087|4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes ESR1 common pathways GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;NCOA2 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent NCOA2;CREB1;ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm NCOA2;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;CREB1;TLR4 GO:0060065| uterus development ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 9649:[DB01183 DB04256] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways GO:0007268| synaptic transmission OPRK1;GRM1;OPRD1;OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1;GRM1 GO:0007626| locomotory behavior OPRM1;GRM1;OPRK1 GO:0000187| activation of MAPK activity TLR4;GRM1 GO:0051930| regulation of sensory perception of pain GRM1;OPRK1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GRM1;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;GRM1;ESR1;OPRM1;OPRD1 9650:[DB01183 DB06538] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06538|Robalzotan HTR1A common genes common pathways GO:0007610| behavior OPRK1;HTR1A GO:0007165| signal transduction OPRD1;OPRM1;ESR1;HTR1A;TLR4;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;HTR1A;OPRK1 9651:[DB01183 DB08156] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1;CA2 GO:0043627| response to estrogen stimulus OPRK1;CA2;ESR1 GO:0045672| positive regulation of osteoclast differentiation CREB1;CA2 GO:2001225| regulation of chloride transport CA2;ABCB1 9652:[DB01183 DB14002] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14002|D-alpha-Tocopherol acetate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0006954| inflammatory response TLR4;ALOX5 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCB;TLR4 GO:0035094| response to nicotine HMOX1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR1I2;ESR1;SEC14L2 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent PPP2CA;CREB1;NR1I2;PRKCB;SEC14L2;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;SOD1 GO:0055114| oxidation-reduction process NQO1;CYP2C8;CYP3A4;GSTO1;HMOX1;SOD1;ALOX5 GO:0043066| negative regulation of apoptotic process ALB;GSTP1;NQO1;GCLC;SOD1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;NQO1;NR1I2;CYP3A4;CES1 GO:0008152| metabolic process GSTP1;UGT1A1;GSTM3;DGKA;GSTA2;CES1;GSTO1 GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;OPRK1 GO:0007626| locomotory behavior OPRK1;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;NR1I2;CREB1 GO:0043065| positive regulation of apoptotic process CREB1;SOD1;HMOX1 GO:0002576| platelet degranulation SOD1;ALB GO:0071260| cellular response to mechanical stimulus TLR4;GCLC GO:0006629| lipid metabolic process TTPA;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NR1I2;SEC14L2;PRKCB;ESR1 GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PRKCB;HMOX1;TLR4 GO:0097190| apoptotic signaling pathway TLR4;PRKCA GO:0045471| response to ethanol NQO1;UGT1A1;OPRK1;GSTP1;SOD1;OPRM1 GO:0001666| response to hypoxia HMOX1;PRKCB;CREB1 GO:0010628| positive regulation of gene expression TLR4;NR1I2 GO:0014823| response to activity GCLC;CREB1 GO:0010033| response to organic substance SOD1;CREB1;UGT1A1;PPP2CA GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity HMOX1;ESR1 GO:0007584| response to nutrient GCLC;TTPA;NQO1;UGT1A1 GO:0007411| axon guidance CREB1;PRKCA GO:0043627| response to estrogen stimulus OPRK1;GSTM3;ESR1;HMOX1 GO:0009636| response to toxin NQO1;TTPA;GSTP1;CES1 GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0001895| retina homeostasis ALB;SOD1 GO:0000187| activation of MAPK activity SOD1;TLR4 GO:0030855| epithelial cell differentiation GSTA2;CES1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PRKCA GO:0035729| cellular response to hepatocyte growth factor stimulus GCLC;CREB1 GO:0030111| regulation of Wnt receptor signaling pathway PPP2CA;ESR1 GO:0098869| ALB;GSTP1;GSTO1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0002376| immune system process TLR4;PRKCB GO:0007165| signal transduction OPRK1;NR1I2;TLR4;CREB1;PRKCB;OPRD1;OPRM1;ESR1 GO:0042167| heme catabolic process UGT1A1;HMOX1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;NR1I2 GO:0032355| response to estradiol stimulus ESR1;GSTP1;NQO1 GO:0006810| transport ABCB1;TTPA GO:0007568| aging GCLC;SOD1;NQO1;CREB1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0071456| cellular response to hypoxia HMOX1;OPRD1 GO:0006468| protein phosphorylation PRKCA;CREB1;PRKCB 9653:[DB01183 DB08190] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;NQO2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NQO2 9654:[DB01183 DB08221] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways GO:0043627| response to estrogen stimulus OPRK1;TEK;ESR1 GO:0010033| response to organic substance TEK;UGT1A1;CREB1 GO:0001666| response to hypoxia TEK;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TEK;TLR4;OPRM1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;TEK;OPRK1;CREB1;TLR4 GO:0006468| protein phosphorylation CREB1;TEK GO:0043066| negative regulation of apoptotic process ALB;TEK 9655:[DB01183 DB04578] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 9656:[DB01183 DB01349] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes CYP3A4 common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;AGTR2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006954| inflammatory response TLR4;AGTR2 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;AGTR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGTR1;OPRM1;OPRD1;ESR1;OPRK1 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0050727| regulation of inflammatory response TLR4;AGTR1;ESR1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0042981| regulation of apoptotic process AGTR2;CREB1;ESR1 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0050729| positive regulation of inflammatory response TLR4;AGTR1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway AGTR2;OPRK1;OPRM1;OPRD1;AGTR1 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ESR1;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;AGTR2;ESR1;OPRM1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0007165| signal transduction AGTR1;OPRD1;OPRM1;ESR1;AGTR2;OPRK1;TLR4;CREB1 9657:[DB01183 DB11774] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 9658:[DB01183 DB04910] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04910|Oxibendazole TUBB4B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4B 9659:[DB01183 DB08772] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0007586| digestion UGT1A1;AKR1B10 GO:0055114| oxidation-reduction process AKR1B10;AKR1B1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;AKR1B10 GO:0010033| response to organic substance CREB1;AKR1B1;UGT1A1 9660:[DB01183 DB08222] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways GO:0006629| lipid metabolic process PNLIP;CYP3A4;CLPS GO:0007586| digestion CLPS;UGT1A1 GO:0032094| response to food CLPS;OPRM1 9661:[DB01183 DB01951] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01951|Gpi-1046 FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TLR4 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FKBP1A GO:0070588| calcium ion transmembrane transport OPRM1;FKBP1A 9662:[DB01183 DB09154] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways GO:0055085| transmembrane transport SLC25A21;SLC13A2;ABCB1;SLC13A5;SLCO1A2;SLC25A1 GO:0006811| ion transport SLCO1A2;SLC13A5;SLC13A2 GO:0006810| transport SLC13A2;ABCB1 9663:[DB01183 DB00140] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways GO:0001666| response to hypoxia MTHFR;CREB1 GO:0055085| transmembrane transport SLC22A6;ABCB1;SLCO1A2 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0042167| heme catabolic process BLVRB;UGT1A1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB GO:0042493| response to drug MTHFR;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;MTHFR;MAOA;CYP2C8;BLVRB GO:0008152| metabolic process MTHFR;CES1;UGT1A1 9664:[DB01183 DB01231] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007165| signal transduction OPRK1;CHRM3;TLR4;CREB1;OPRD1;OPRM1;CHRM2;CHRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM2;CHRM1;OPRK1;CHRM3 GO:0007586| digestion CHRM3;UGT1A1 9665:[DB01183 DB00710] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00710|Ibandronate FDPS common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2C8;UGT1A1 GO:0016032| viral reproduction FDPS;CREB1 GO:0006695| cholesterol biosynthetic process CES1;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 9666:[DB01183 DB00144] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;SCARB1 GO:0007165| signal transduction CREB1;TLR4;DGKD;OPRK1;ESR1;DGKG;OPRM1;OPRD1 GO:0045332| phospholipid translocation ATP8A1;ABCB1 GO:0006468| protein phosphorylation PRKCA;CREB1 GO:0032497| detection of lipopolysaccharide SCARB1;TLR4 GO:0007411| axon guidance PRKCA;CREB1 GO:0010033| response to organic substance CREB1;UGT1A1;DGKD GO:0034375| high-density lipoprotein particle remodeling SCARB1;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PRKCA GO:0008152| metabolic process CES1;DGKG;UGT1A1;DGKD GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;SCARB1 GO:0006629| lipid metabolic process PTDSS1;PISD;CYP3A4;SMPD3;PTDSS2 GO:0042060| wound healing SCARB1;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;PRKCA GO:0051000| positive regulation of nitric-oxide synthase activity SCARB1;ESR1 GO:0016032| viral reproduction SCARB1;CREB1 9667:[DB01183 DB00511] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways GO:0006811| ion transport ATP1A1;SLCO1A2 GO:0071260| cellular response to mechanical stimulus TLR4;ATP1A1 GO:0042493| response to drug ATP1A1;ABCB1;CREB1;UGT1A1 9668:[DB01183 DB00917] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes SLCO1A2 common pathways GO:0042493| response to drug ABCB1;CREB1;UGT1A1;ABCC4 GO:0007268| synaptic transmission OPRD1;OPRM1;PTGDR2;OPRK1 GO:0055114| oxidation-reduction process CYP2C8;CYP19A1;ABCC4;CYP11A1;CYP3A4 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0006955| immune response OPRD1;PTGDR2;TLR4;PTGER4;OPRK1 GO:0032496| response to lipopolysaccharide PTGER2;OPRM1;PTGER1;UGT1A1;PTGER4;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;PTGER3;OPRD1;OPRM1 GO:0060065| uterus development ESR1;CYP19A1 GO:0007218| neuropeptide signaling pathway OPRK1;OPRD1;OPRM1;PTGDR2 GO:0002576| platelet degranulation ALB;ABCC4 GO:0071260| cellular response to mechanical stimulus TLR4;PTGER4 GO:0006629| lipid metabolic process CYP3A4;CYP11A1 GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0009636| response to toxin SLC22A8;CES1 GO:0006811| ion transport SLCO3A1;SLCO1A2;SLCO1B1;SLC22A8;SLC22A11;SLCO4A1;SLC22A7;SLCO1C1;SLCO2B1;SLC22A2 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0055085| transmembrane transport ABCC4;SLC22A11;SLC22A7;SLCO4A1;SLCO1A2;SLCO3A1;SLCO1B1;SLC22A8;ABCB1;SLCO2B1;SLC22A2;SLC51B;ABCC5;SLCO1C1;SLCO2A1;SLC22A6;SLC51A GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1A2;SLC51A;SLCO1C1;SLC51B;ALB;SLCO2B1 GO:0010033| response to organic substance ABCC4;CREB1;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGDR2;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP11A1;CYP3A4;UGT1A1;CYP2C8 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1B1;SLCO1A2;SLCO3A1;SLC22A7;SLCO4A1;SLC22A11;SLC22A6;SLCO2A1;SLCO1C1;SLCO2B1;ALB GO:0050729| positive regulation of inflammatory response TLR4;PTGER4 GO:0007186| G-protein coupled receptor signaling pathway PTGER2;PTGDR2;OPRM1;PTGER1;OPRD1;PTGER3;OPRK1;PTGER4 GO:0006810| transport ABCC5;ABCB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1;PTGDR2 GO:0015711| organic anion transport SLCO1B1;SLCO1A2;SLC22A7;SLC22A11;SLC22A6;SLCO1C1;SLC22A2;ABCC5 GO:0007165| signal transduction TLR4;CREB1;PTGER4;OPRK1;ESR1;OPRD1;PTGER3;OPRM1;PTGER1;PTGDR2;PTGER2 9669:[DB01183 DB08353] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08353|2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;CSNK2A1;CREB1 GO:0048511| rhythmic process CREB1;CSNK2A1 GO:0007165| signal transduction ESR1;CSNK2A1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 9670:[DB01183 DB03292] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways 9671:[DB01183 DB07700] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0000060| protein import into nucleus, translocation OPRD1;AKR1C3 GO:0055114| oxidation-reduction process AKR1C3;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;AKR1C3 GO:0009267| cellular response to starvation ALB;AKR1C3 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;AKR1C3;OPRD1;OPRM1 GO:0007584| response to nutrient AKR1C3;UGT1A1 GO:0008584| male gonad development ESR1;AKR1C3 9672:[DB01183 DB01271] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01271|Idursulfase PLIN3 common genes common pathways 9673:[DB01183 DB07680] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07680|[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID CMA1 common genes common pathways GO:0050727| regulation of inflammatory response TLR4;CMA1;ESR1 9674:[DB01183 DB04951] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0044267| cellular protein metabolic process FURIN;ALB GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FURIN 9675:[DB01183 DB04957] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes CYP3A4 common pathways GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP3A5;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;CYP1A1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP3A5;CYP2C8;CYP1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0032094| response to food OPRM1;CYP1A1 GO:0042493| response to drug UGT1A1;CYP1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP1A1;UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 GO:0007568| aging CREB1;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A1;UGT1A1;CYP3A5;CYP2C8 GO:1901381| KCNQ1;OPRK1;KCNE1;KCNH2 GO:0010033| response to organic substance CREB1;CYP1A1;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0055085| transmembrane transport KCNH2;SLCO1A2;KCNQ1;ABCB1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8;CYP3A5;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0009636| response to toxin CES1;CYP1A1 GO:0006811| ion transport KCNQ1;SLCO1A2;KCNE1;KCNH2 9676:[DB01183 DB04919] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04919|Alfimeprase FGA;FGB common genes common pathways GO:0044267| cellular protein metabolic process ALB;FGA GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;FGA;OPRM1;FGB GO:0002224| toll-like receptor signaling pathway FGA;TLR4;FGB GO:0002376| immune system process FGA;TLR4;FGB GO:0007165| signal transduction TLR4;CREB1;FGA;OPRK1;OPRD1;OPRM1;ESR1;FGB GO:0043687| post-translational protein modification FGA;ALB GO:0002576| platelet degranulation FGB;ALB;FGA GO:0045087| innate immune response FGA;TLR4;FGB 9677:[DB01183 DB05679] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways GO:0002376| immune system process IL23A;TLR4 GO:0050729| positive regulation of inflammatory response IL23A;TLR4;IL12B GO:0032735| positive regulation of interleukin-12 production IL23A;TLR4;IL12B GO:0032700| negative regulation of interleukin-17 production TLR4;IL12B GO:0010033| response to organic substance CREB1;UGT1A1;IL12B GO:0042346| positive regulation of NF-kappaB import into nucleus IL23A;TLR4;IL12B GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;IL23A GO:0050829| defense response to Gram-negative bacterium IL23A;IL12B;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;IL12B;OPRK1 GO:0045672| positive regulation of osteoclast differentiation IL23A;CREB1;IL12B GO:0042088| T-helper 1 type immune response IL12B;TLR4 GO:0045087| innate immune response TLR4;IL23A GO:0032733| positive regulation of interleukin-10 production TLR4;IL12B;IL23A GO:0050671| positive regulation of lymphocyte proliferation IL12B;TLR4 GO:0032729| positive regulation of interferon-gamma production IL23A;IL12B;TLR4 GO:0019233| sensory perception of pain OPRK1;IL12B;OPRD1;OPRM1 GO:0006955| immune response OPRD1;IL23A;TLR4;OPRK1 GO:0006954| inflammatory response IL23A;TLR4 GO:0032609| interferon-gamma production IL12B;TLR4 GO:0032760| positive regulation of tumor necrosis factor production IL12B;TLR4;IL23A GO:0051607| defense response to virus IL12B;OPRK1;IL23A 9678:[DB01183 DB13203] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 9679:[DB01183 DB06479] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PDE4A;OPRK1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;PDE4A;OPRM1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 9680:[DB01183 DB08885] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:1900745| VEGFA;OPRK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0060749| mammary gland alveolus development VEGFA;ESR1 GO:0043066| negative regulation of apoptotic process VEGFA;VEGFB;ALB GO:0002576| platelet degranulation ALB;VEGFB;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;ESR1;CREB1;TLR4 GO:0010629| negative regulation of gene expression VEGFB;ESR1;VEGFA;OPRD1;CREB1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;VEGFB;PGF GO:0007595| lactation VEGFA;CREB1 GO:0030154| cell differentiation CREB1;PGF;VEGFA GO:0071456| cellular response to hypoxia OPRD1;VEGFA GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0007165| signal transduction PGF;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA GO:0032870| cellular response to hormone stimulus PGF;UGT1A1 GO:0031100| organ regeneration UGT1A1;PGF GO:0030855| epithelial cell differentiation VEGFA;CES1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;VEGFB;VEGFA;OPRM1 GO:0001666| response to hypoxia PGF;VEGFA;VEGFB;CREB1 GO:0010628| positive regulation of gene expression TLR4;VEGFA 9681:[DB01183 DB03832] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways GO:0051791| medium-chain fatty acid metabolic process CES1;CROT GO:0006629| lipid metabolic process CROT;CYP3A4 9682:[DB01183 DB02353] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CCL5;OPRM1;OPRD1;OPRK1 GO:0009636| response to toxin CCL5;CES1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;CCL5 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;CCL5 GO:0006955| immune response OPRD1;CCL5;TLR4;OPRK1 GO:0006954| inflammatory response TLR4;CCL5 GO:0043491| protein kinase B signaling cascade CREB1;CCL5 9683:[DB01183 DB11760] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;PARP1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0006366| transcription from RNA polymerase II promoter ESR1;PARP1;CREB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCG2 GO:1904646| TLR4;PARP1 GO:0006351| transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:1901529| ABCB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;PARP1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PARP1;ESR1;CREB1 9684:[DB01183 DB08750] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0032496| response to lipopolysaccharide TLR4;NOS2;UGT1A1;OPRM1 GO:0007623| circadian rhythm CREB1;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;NOS2 GO:0055114| oxidation-reduction process NOS2;CYP2C8;CYP3A4 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0009617| response to bacterium NOS2;TLR4 9685:[DB01183 DB02691] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes SLCO1A2 common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1;SLCO1A2 GO:0015711| organic anion transport SLCO1A2;SLCO1B1;SLCO1B3 GO:0055085| transmembrane transport SLCO1A2;SLCO1B3;SLCO1B1;ABCB1 GO:0006811| ion transport SLCO1A2;SLCO1B3;SLCO1B1 GO:0008285| negative regulation of cell proliferation OPRM1;FABP6 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;SLCO1A2;ALB;FABP6 GO:0006629| lipid metabolic process CYP3A4;FABP6 9686:[DB01183 DB00614] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00614|Furazolidone MAOB;MAOA common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;UGT1A1;TLR4;OPRM1 GO:0045471| response to ethanol OPRK1;UGT1A1;MAOB;OPRM1 GO:0042493| response to drug ABCB1;CREB1;MAOB;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;MAOB;CYP3A4;MAOA GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0009636| response to toxin MAOB;CES1 9687:[DB01183 DB01733] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01733|L-Phospholactate PKM common genes common pathways GO:0010033| response to organic substance CREB1;UGT1A1;PKM GO:0007584| response to nutrient PKM;UGT1A1 GO:0001666| response to hypoxia PKM;CREB1 GO:0032868| response to insulin stimulus OPRK1;PKM GO:0031100| organ regeneration UGT1A1;PKM GO:0008152| metabolic process PKM;CES1;UGT1A1 GO:0001889| liver development PKM;UGT1A1 9688:[DB01183 DB05514] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05514|Cobiprostone CLCN2 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;CLCN2;ABCB1 GO:0006811| ion transport SLCO1A2;CLCN2 GO:0006810| transport ABCB1;CLCN2 9689:[DB01183 DB07831] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways GO:0071222| cellular response to lipopolysaccharide TLR4;ABL1;OPRK1 GO:0043065| positive regulation of apoptotic process CREB1;ABL1 GO:0045087| innate immune response ABL1;TLR4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CREB1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1;ESR1 GO:0006468| protein phosphorylation ABL1;CREB1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;ABL1 GO:0002322| B cell proliferation involved in immune response TLR4;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ABL1;TLR4;OPRM1 9690:[DB01183 DB01272] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01272|Alglucosidase alfa M6PR common genes common pathways GO:0006898| receptor-mediated endocytosis M6PR;ALB GO:0007165| signal transduction M6PR;OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 9691:[DB01183 DB04794] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;UGT1A1;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2B6;UGT1A1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0060065| uterus development ESR1;CYP19A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CES1;CYP2B6;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2B6 GO:0042493| response to drug CYP2E1;ABCB1;UGT1A1;CREB1 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP19A1;CYP2B6;CYP2C8;CYP2E1;CYP3A4 9692:[DB01183 DB00769] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;NR3C1;CREB1;TLR4;OPRK1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0042737| drug catabolic process CYP3A4 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 9693:[DB01183 DB07396] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways GO:0070266| necroptosis PYGL;TLR4 GO:0008152| metabolic process UGT1A1;PYGL;CES1 9694:[DB01183 DB05796] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05796|Daglutril MME common genes common pathways GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;MME 9695:[DB01183 DB00078] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:1904646| FCGR2B;TLR4 GO:0007165| signal transduction OPRM1;OPRD1;FCGR2C;ESR1;CREB1;FCGR2B;TLR4;OPRK1;FCGR1A GO:0002376| immune system process C1QC;C1S;C1QA;C1R;C1QB;TLR4;FCGR2A;FCGR1A GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB GO:0009617| response to bacterium FCGR2B;TLR4 GO:0006954| inflammatory response FCGR2B;TLR4 GO:0006955| immune response FCGR3B;FCGR2B;TLR4;C1R;FCGR1A;OPRK1;C1QC;FCGR2C;OPRD1;FCGR3A GO:0016032| viral reproduction FCGR2B;CREB1 GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0045087| innate immune response FCGR1A;C1QB;C1R;TLR4;C1QA;C1S;C1QC 9696:[DB01183 DB09140] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0006811| ion transport NOX1;SLCO1A2 GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB GO:0098869| ALB;HBB;HBA1 GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;TLR4;ESR1;OPRM1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;NOX1;TLR4;CREB1 GO:0007568| aging CREB1;MT-CO1 GO:0006954| inflammatory response NOX1;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOX1;MT-CO1;CYP3A4 GO:0046330| positive regulation of JNK cascade TLR4;NOX1 9697:[DB01183 DB01237] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01237|Bromodiphenhydramine HRH1;SLC22A6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HRH1;OPRD1;OPRM1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLCO1A2 GO:0007613| memory CREB1;HRH1 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;HRH1;OPRD1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC22A6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;HRH1;OPRM1;OPRK1 GO:0006954| inflammatory response TLR4;HRH1 GO:0008542| visual learning HRH1;CREB1 9698:[DB01183 DB08259] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways GO:0009636| response to toxin CES1;EPHX2 GO:0010628| positive regulation of gene expression EPHX2;TLR4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;EPHX2;CYP3A4 GO:0006954| inflammatory response EPHX2;TLR4 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 GO:0008152| metabolic process UGT1A1;CES1;EPHX2 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2;CES1;CYP2C8 GO:0006629| lipid metabolic process EPHX2;CYP3A4 9699:[DB01183 DB01738] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01738|Phosphorylcolamine PRKCB common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCB;TLR4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PRKCB GO:0006351| transcription, DNA-dependent CREB1;ESR1;PRKCB GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PRKCB;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PRKCB GO:0001666| response to hypoxia CREB1;PRKCB GO:0007165| signal transduction OPRD1;OPRM1;ESR1;PRKCB;TLR4;CREB1;OPRK1 GO:0002376| immune system process PRKCB;TLR4 GO:0006468| protein phosphorylation CREB1;PRKCB 9700:[DB01183 DB06814] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06814|Protokylol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ADRB2;ESR1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;OPRK1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:1904646| TLR4;ADRB2 9701:[DB01183 DB07919] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8 9702:[DB01183 DB03945] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways GO:0010628| positive regulation of gene expression CRP;TLR4 GO:0006953| acute-phase response CRP;UGT1A1 GO:0006954| inflammatory response CRP;TLR4 9703:[DB01183 DB09064] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09064|Ciprofibrate PPARA common genes common pathways GO:0048511| rhythmic process CREB1;PPARA GO:0001666| response to hypoxia CREB1;PPARA GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0042752| regulation of circadian rhythm CREB1;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARA GO:1901215| CREB1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARA;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PPARA GO:0006629| lipid metabolic process CYP3A4;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARA;TLR4;CREB1 GO:0043401| steroid hormone mediated signaling pathway PPARA;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;PPARA GO:0042060| wound healing OPRM1;PPARA 9704:[DB01183 DB03451] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;VDR;CREB1;TLR4;OPRK1 GO:0010628| positive regulation of gene expression TLR4;VDR GO:0008285| negative regulation of cell proliferation VDR;OPRM1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;VDR;CREB1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VDR GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;VDR GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0007595| lactation VDR;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;VDR 9705:[DB01183 DB12118] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12118|Sotatercept ACVR2A common genes common pathways GO:0006468| protein phosphorylation CREB1;ACVR2A GO:0008584| male gonad development ACVR2A;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ACVR2A;CREB1;TLR4;ESR1 9706:[DB01183 DB02039] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1;KAT5 GO:0006351| transcription, DNA-dependent CREB1;ESR1;KAT5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;KAT5;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;KAT5 GO:0006355| regulation of transcription, DNA-dependent ESR1;KAT5;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;KAT5;CREB1 GO:0016032| viral reproduction CREB1;KAT5 9707:[DB01183 DB05234] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05234|LGD2941 AR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;AR GO:0016579| protein deubiquitination AR;ESR1 GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction OPRD1;OPRM1;ESR1;AR;TLR4;CREB1;OPRK1 9708:[DB01183 DB05542] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05542|Naronapride HTR4 common genes common pathways GO:0007268| synaptic transmission OPRD1;HTR4;OPRM1;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR4;OPRM1;OPRD1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;HTR4;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HTR4;OPRD1;OPRK1 9709:[DB01183 DB04757] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug ABCB1;CREB1;PNP;UGT1A1 GO:0006955| immune response OPRD1;OPRK1;PNP;TLR4 9710:[DB01183 DB03435] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways 9711:[DB01183 DB04244] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04244|(2R)-2-(3-Biphenylyl)-N-{(2R)-2-hydroxy-3-[(2-pyridinylsulfonyl)amino]propyl}-4-methylpentanamide CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway CTSK;TLR4 9712:[DB01183 DB08159] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0048511| rhythmic process TOP1;CREB1 GO:0007623| circadian rhythm TOP1;CREB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;TOP1 GO:0016032| viral reproduction CREB1;TOP1 9713:[DB01183 DB08101] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0044267| cellular protein metabolic process ALB;TTR 9714:[DB01183 DB12688] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways GO:0042493| response to drug EEF2;ABCB1;CREB1;UGT1A1 GO:0045471| response to ethanol OPRK1;UGT1A1;EEF2;OPRM1 GO:0032355| response to estradiol stimulus EEF2;ESR1 GO:0007568| aging EEF2;CREB1 9715:[DB01183 DB02282] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 9716:[DB01183 DB06039] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06039|PA-1050040 gag common genes common pathways 9717:[DB01183 DB02311] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A GO:0070588| calcium ion transmembrane transport OPRM1;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FKBP1A 9718:[DB01183 DB04069] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways GO:0006468| protein phosphorylation DAPK1;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;DAPK1;CREB1;TLR4;OPRK1 GO:0097190| apoptotic signaling pathway DAPK1;TLR4 GO:0043066| negative regulation of apoptotic process DAPK1;ALB GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;DAPK1 GO:0042981| regulation of apoptotic process CREB1;ESR1;DAPK1 9719:[DB01183 DB00178] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0006811| ion transport SLC15A1;SLC15A2;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;SLC15A2;SLC15A1;ABCB1 GO:0007165| signal transduction BDKRB1;TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;BDKRB1;OPRK1 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;BDKRB1 GO:0006954| inflammatory response BDKRB1;TLR4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;BCHE GO:0007586| digestion UGT1A1;SLC15A1 GO:0032496| response to lipopolysaccharide BDKRB1;UGT1A1;TLR4;OPRM1 GO:0019233| sensory perception of pain OPRK1;BDKRB1;OPRM1;OPRD1 9720:[DB01183 DB00592] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:1901215| CREB1;GABRB3 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CES1 GO:0006811| ion transport SLCO1A2;GABRB3 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006810| transport GABRB3;ABCB1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction GABRB3;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 9721:[DB01183 DB01160] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGIR;OPRM1;OPRD1 GO:0010628| positive regulation of gene expression TLR4;PTGFR GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0055085| transmembrane transport ABCB1;SLC22A2;SLCO2A1;SLC22A6;SLC22A11;SLC22A7;SLCO1A2;SLCO3A1;SLC22A8 GO:0006811| ion transport SLCO3A1;SLCO1A2;SLC22A8;SLC22A11;SLC22A7;SLC22A2 GO:0009636| response to toxin CES1;SLC22A8 GO:0007165| signal transduction PTGFR;ESR1;OPRD1;OPRM1;OPRK1;PTGIR;TLR4;CREB1 GO:0015711| organic anion transport SLC22A7;SLC22A11;SLCO1A2;SLC22A2;SLC22A6 GO:0032355| response to estradiol stimulus ESR1;PTGFR GO:0007186| G-protein coupled receptor signaling pathway PTGIR;OPRK1;OPRD1;OPRM1;PTGFR GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO3A1;SLCO1A2;SLC22A7;SLC22A11;SLC22A6;SLCO2A1;ALB GO:0043066| negative regulation of apoptotic process PTGFR;ALB GO:0032496| response to lipopolysaccharide OPRM1;PTGFR;TLR4;PTGIR;UGT1A1 9722:[DB01183 DB13996] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0006811| ion transport ATP1A1;SLCO1A2 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;ATP1A1 9723:[DB01183 DB09571] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09571|Levmetamfetamine PNMT common genes common pathways 9724:[DB01183 DB00815] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00815|Sodium lauryl sulfate ALB common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB 9725:[DB01183 DB03253] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 9726:[DB01183 DB00925] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1;CREB1;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0002576| platelet degranulation ALB;CALM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;ADRA1B;ADRA1D;OPRK1;ADRA1A GO:1904646| TLR4;ADRB2 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0006811| ion transport SLC22A2;SLC22A1;SLC22A3;SLCO1A2 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1;ADRA2C GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0055085| transmembrane transport SLC22A3;SLCO1A2;CALM1;SLC22A1;SLC22A2;ABCB1 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0015711| organic anion transport SLCO1A2;SLC22A3;SLC22A2;SLC22A1 GO:0007165| signal transduction ADRA1B;OPRM1;OPRD1;ESR1;ADRA2C;ADRB2;ADRA2B;ADRA1A;ADRA2A;OPRK1;ADRA1D;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;ADRA2A;OPRK1;ADRA1A;ADRA2C;ADRA2B;ADRB2;OPRM1;OPRD1;CALM1;ADRA1B GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1D;ADRA1B;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A GO:0007568| aging CREB1;ADRA1A 9727:[DB01183 DB12418] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12418|Saccharin CA3 common genes common pathways GO:0045471| response to ethanol OPRM1;CA3;UGT1A1;OPRK1 9728:[DB01183 DB07837] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways GO:0006468| protein phosphorylation SGK1;CREB1 GO:0042981| regulation of apoptotic process ESR1;CREB1;SGK1 9729:[DB01183 DB01811] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways GO:0006355| regulation of transcription, DNA-dependent LTF;ESR1;CREB1 GO:0042742| defense response to bacterium LTF;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;LTF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;TLR4 GO:0006351| transcription, DNA-dependent ESR1;LTF;CREB1 GO:0050829| defense response to Gram-negative bacterium TLR4;LTF GO:0043066| negative regulation of apoptotic process ALB;LTF GO:0045087| innate immune response TLR4;LTF GO:0006811| ion transport SLCO1A2;LTF GO:0001895| retina homeostasis ALB;LTF GO:0044267| cellular protein metabolic process ALB;LTF GO:0002376| immune system process LTF;TLR4 9730:[DB01183 DB00449] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0042493| response to drug CREB1;BCHE;UGT1A1;ABCB1;ADRA1A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;OPRM1;ESR1 GO:0007568| aging CREB1;ADRA1A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;OPRK1;ADRA1A;ADRB2;OPRM1;OPRD1 GO:0007165| signal transduction ESR1;ADRB2;OPRM1;OPRD1;CREB1;TLR4;ADRA2A;OPRK1;ADRA1A GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0007584| response to nutrient UGT1A1;BCHE GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE;ADRA1A GO:1904646| ADRB2;TLR4 9731:[DB01183 DB12061] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0035094| response to nicotine CREB1;DRD2 GO:0008542| visual learning DRD3;CREB1;DRD2 GO:0043278| response to morphine DRD3;OPRK1;DRD2;OPRM1 GO:0042752| regulation of circadian rhythm DRD4;CREB1 GO:0048149| behavioral response to ethanol DRD2;DRD4;OPRM1 GO:0042493| response to drug UGT1A1;DRD3;CREB1;ABCB1;DRD2 GO:0048148| behavioral response to cocaine DRD3;OPRK1;DRD2;DRD4 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;OPRM1 GO:0007626| locomotory behavior OPRM1;DRD3;OPRK1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD3;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0045471| response to ethanol OPRK1;DRD2;DRD3;UGT1A1;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0048511| rhythmic process CREB1;DRD4 GO:0009636| response to toxin CES1;DRD2 GO:0007409| axonogenesis CREB1;DRD2 GO:0000187| activation of MAPK activity DRD4;TLR4 GO:0042220| response to cocaine OPRM1;DRD3;DRD2;OPRK1 GO:0008344| adult locomotory behavior OPRD1;DRD4 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:1900273| DRD2;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;DRD4;HTR1A;ESR1;DRD2;OPRK1;CREB1;DRD3;TLR4 GO:0007610| behavior OPRK1;HTR1A GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;DRD4;HTR1A;DRD3;DRD2;OPRK1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 9732:[DB01183 DB06215] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0008285| negative regulation of cell proliferation FTH1;OPRM1 GO:0006811| ion transport TF;SLCO1A2 GO:0001895| retina homeostasis TF;ALB GO:0044267| cellular protein metabolic process ALB;TF GO:0006955| immune response OPRK1;TLR4;FTH1;OPRD1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;FTH1 GO:0043687| post-translational protein modification ALB;TF GO:0002576| platelet degranulation TF;ALB 9733:[DB01183 DB01444] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes OPRM1;OPRD1 common pathways GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0042755| eating behavior OPRK1;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1 GO:0051881| regulation of mitochondrial membrane potential OPRD1 GO:0042220| response to cocaine OPRK1;OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0044849| OPRK1;OPRM1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071456| cellular response to hypoxia OPRD1 GO:0038003| opioid receptor signaling pathway OPRM1;OPRD1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1 GO:0006955| immune response OPRK1;TLR4;OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0097237| OPRD1 GO:0032100| positive regulation of appetite OPRM1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0007600| sensory perception OPRK1;OPRM1 GO:0043278| response to morphine OPRM1;OPRK1 GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0048149| behavioral response to ethanol OPRM1 GO:0032094| response to food OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1 GO:0009314| response to radiation OPRM1;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0042060| wound healing OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1 9734:[DB01183 DB09167] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0008542| visual learning HRH1;CREB1 GO:0016032| viral reproduction CREB1;HTR2A GO:0006954| inflammatory response HRH1;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C8;CYP2C19 GO:0007268| synaptic transmission OPRM1;OPRD1;HTR2A;SLC6A2;OPRK1 GO:0042493| response to drug HTR2A;CYP1A2;SLC6A4;CREB1;SLC6A2;UGT1A1;ABCB1;ADRA1A GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0007586| digestion CHRM3;UGT1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2C9;CYP2D6;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP2C19;CYP2C8 GO:0019233| sensory perception of pain OPRM1;OPRD1;HTR2A;OPRK1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;OPRM1;OPRD1;HRH1;ESR1;HTR2A;ADRA1A;OPRK1;ADRA1D GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;UGT1A1;CYP3A4;CYP1A2 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0010033| response to organic substance SLC6A4;CYP1A2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;HTR2A;OPRM1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLCO1A2;SLC6A4 GO:0009636| response to toxin CES1;SLC6A4 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADRA2C;OPRK1 GO:0007165| signal transduction ADRA1B;HTR2A;ADRA2B;CHRM2;HTR1A;ADRA2C;CHRM1;ESR1;OPRD1;HRH1;OPRM1;CHRM5;OPRK1;ADRA2A;CHRM4;ADRA1A;TLR4;CREB1;CHRM3;ADRA1D GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP1A2;CYP3A4 GO:0007610| behavior HTR1A;HTR2A;OPRK1 GO:0097267| CYP1A2;CYP2C19;CYP2C8;CYP2C9 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2C8;CYP2D6 GO:0006810| transport SLC6A2;ABCB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 GO:0007568| aging HTR2A;ADRA1A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;ADRA1B;ADRA1D;ADRA1A GO:0007613| memory SLC6A4;HRH1;HTR2A;CREB1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2C9;UGT1A1;CYP3A4;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;ADRA1D;CHRM4;ADRA1A;OPRK1;ADRA2A;OPRD1;HRH1;OPRM1;CHRM5;HTR2A;ADRA2B;CHRM2;HTR1A;ADRA2C;CHRM1;ADRA1B GO:0032355| response to estradiol stimulus SLC6A4;CYP1A2;ESR1 9735:[DB01183 DB05417] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05417|GW 468816 GLRA1 common genes common pathways GO:0006811| ion transport SLCO1A2;GLRA1 GO:0007218| neuropeptide signaling pathway GLRA1;OPRK1;OPRM1;OPRD1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0071294| cellular response to zinc ion CREB1;GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA1 GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;GLRA1 9736:[DB01183 DB02338] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;AASS GO:0055114| oxidation-reduction process CYP3A4;DPYD;TXNRD1;AASS;CYP2C8 GO:0007165| signal transduction TXNRD1;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0098869| TXNRD1;ALB 9737:[DB01183 DB01973] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways GO:0007586| digestion UGT1A1;PRSS2 9738:[DB01183 DB02508] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;FDPS GO:0016032| viral reproduction CREB1;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006695| cholesterol biosynthetic process FDPS;CES1 9739:[DB01183 DB02473] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02473|6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;PLAU GO:0001666| response to hypoxia CREB1;PLAU 9740:[DB01183 DB08493] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08493|5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID MMP7 common genes common pathways GO:0044849| OPRM1;MMP7;OPRK1 GO:0007568| aging CREB1;MMP7 GO:0071260| cellular response to mechanical stimulus MMP7;TLR4 9741:[DB01183 DB09340] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09340|Tyropanoic acid GUSB common genes common pathways GO:0008152| metabolic process GUSB;CES1;UGT1A1 9742:[DB01183 DB06248] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06248|Amelubant LTB4R2;LTB4R common genes common pathways GO:0007165| signal transduction OPRK1;LTB4R2;TLR4;CREB1;ESR1;OPRD1;LTB4R;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;LTB4R;OPRD1;LTB4R2;OPRK1 GO:0007218| neuropeptide signaling pathway OPRM1;LTB4R;OPRD1;LTB4R2;OPRK1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;LTB4R2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LTB4R2;OPRK1;OPRD1;OPRM1;LTB4R;ESR1 GO:0006955| immune response OPRK1;TLR4;OPRD1;LTB4R GO:0006954| inflammatory response TLR4;LTB4R 9743:[DB01183 DB04685] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways GO:0001889| liver development UGT1A1;DUT GO:0014070| response to organic cyclic compound UGT1A1;DUT 9744:[DB01183 DB04072] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04072|Alpha-Methylisocitric Acid ACO2 common genes common pathways GO:0001889| liver development UGT1A1;ACO2 GO:0008152| metabolic process ACO2;UGT1A1;CES1 9745:[DB01183 DB00030] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0014070| response to organic cyclic compound IGFBP7;UGT1A1 GO:0050769| positive regulation of neurogenesis LRP2;OPRM1 GO:0000187| activation of MAPK activity INSR;TLR4 GO:0044267| cellular protein metabolic process ALB;IGFBP7 GO:0008584| male gonad development ESR1;LRP2;INSR GO:1904646| TLR4;IGF1R GO:0042359| vitamin D metabolic process LRP2;CYP3A4 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity RB1;ESR1 GO:0008285| negative regulation of cell proliferation IGFBP7;RB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway INSR;OPRK1;OPRD1;OPRM1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1;RB1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;INSR GO:0006338| chromatin remodeling RB1;ESR1 GO:0006468| protein phosphorylation CREB1;INSR;IGF1R GO:0007613| memory INSR;CREB1 GO:0006898| receptor-mediated endocytosis ALB;LRP2 GO:0032870| cellular response to hormone stimulus UGT1A1;IGFBP7 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;INSR GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;IGF1R;ESR1 GO:0010629| negative regulation of gene expression RB1;OPRD1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;INSR;ESR1;RB1 GO:0045893| positive regulation of transcription, DNA-dependent INSR;CREB1;RB1;ESR1 GO:0043687| post-translational protein modification ALB;IGFBP7 GO:0060068| vagina development LRP2;ESR1 GO:0006955| immune response OPRD1;IGF1R;OPRK1;TLR4 GO:0016032| viral reproduction RB1;IDE;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RB1 GO:0006351| transcription, DNA-dependent RB1;ESR1;CREB1 GO:0002576| platelet degranulation SYTL4;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RB1;CREB1;TLR4 GO:0007218| neuropeptide signaling pathway OPRM1;CPE;OPRD1;OPRK1 GO:0008152| metabolic process UGT1A1;IDE;PCSK1;CPE;CES1 GO:0043066| negative regulation of apoptotic process ALB;IGF1R GO:0000122| negative regulation of transcription from RNA polymerase II promoter RB1;ESR1 GO:0006629| lipid metabolic process LRP2;CYP3A4 9746:[DB01183 DB08482] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08482|[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER MMP1 common genes common pathways GO:0044267| cellular protein metabolic process MMP1;ALB GO:0016032| viral reproduction CREB1;MMP1 9747:[DB01183 DB07696] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways GO:0035094| response to nicotine CASP3;CREB1 GO:0042493| response to drug CASP3;ABCB1;CREB1;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0097190| apoptotic signaling pathway TLR4;CASP3 GO:0042060| wound healing CASP3;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CASP3;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;CASP3 GO:0001666| response to hypoxia CREB1;CASP3 GO:0014070| response to organic cyclic compound CASP3;UGT1A1 GO:0051384| response to glucocorticoid stimulus CASP3;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;CASP3 9748:[DB01183 DB03650] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03650|(3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One PIM1 common genes common pathways GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 GO:0006468| protein phosphorylation PIM1;CREB1 GO:0043066| negative regulation of apoptotic process PIM1;ALB 9749:[DB01183 DB14600] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14600|Edetate disodium anhydrous ADA;CYP1A2;PON3;CYP19A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0043066| negative regulation of apoptotic process ADA;ALB GO:0060065| uterus development CYP19A1;ESR1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1 GO:0001889| liver development UGT1A1;ADA GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0043278| response to morphine OPRK1;ADA;OPRM1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;ADA;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0007568| aging CREB1;ADA GO:0001666| response to hypoxia ADA;CREB1 GO:0030890| positive regulation of B cell proliferation ADA;TLR4 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0009636| response to toxin CES1;PON3 GO:0030879| mammary gland development CREB1;CYP19A1 9750:[DB01183 DB06457] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06457|Tecastemizole KCNH2 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;KCNH2;ABCB1 GO:0006811| ion transport SLCO1A2;KCNH2 GO:1901381| OPRK1;KCNH2 9751:[DB01183 DB05413] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05413|Tifuvirtide SERPINA5 common genes common pathways 9752:[DB01183 DB07117] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways GO:0043065| positive regulation of apoptotic process MMP9;CREB1 GO:0043066| negative regulation of apoptotic process ALB;MMP9 9753:[DB01183 DB06371] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06371|Siplizumab CD2 common genes common pathways GO:0032760| positive regulation of tumor necrosis factor production CD2;TLR4 9754:[DB01183 DB06602] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06602|Reslizumab IL5 common genes common pathways GO:0030890| positive regulation of B cell proliferation IL5;TLR4 GO:0006954| inflammatory response TLR4;IL5 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;IL5 GO:0006955| immune response OPRD1;IL5;TLR4;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;IL5;ESR1 9755:[DB01183 DB04119] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways GO:0006468| protein phosphorylation CAMK2A;CREB1 GO:0030154| cell differentiation CREB1;CAMK2A GO:0051092| positive regulation of NF-kappaB transcription factor activity CAMK2A;TLR4 9756:[DB01183 DB07930] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways GO:0006629| lipid metabolic process ACOX1;CYP3A4 GO:0008152| metabolic process ACOX1;UGT1A1;CES1 GO:0055114| oxidation-reduction process ACOX1;CYP2C8;CYP3A4 9757:[DB01183 DB11949] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11949|Vestipitant TACR1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;TACR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1;TACR1 GO:0007204| elevation of cytosolic calcium ion concentration TACR1;OPRM1;ESR1 GO:0007165| signal transduction OPRM1;TACR1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0014070| response to organic cyclic compound TACR1;UGT1A1 GO:0042755| eating behavior OPRD1;TACR1;OPRM1;OPRK1 GO:0050671| positive regulation of lymphocyte proliferation TLR4;TACR1 GO:0019233| sensory perception of pain OPRK1;OPRD1;TACR1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;TACR1;OPRM1;OPRD1;ESR1 GO:0045471| response to ethanol OPRM1;TACR1;UGT1A1;OPRK1 GO:0007268| synaptic transmission OPRD1;TACR1;OPRM1;OPRK1 GO:0006954| inflammatory response TLR4;TACR1 GO:0035094| response to nicotine TACR1;CREB1 GO:0043278| response to morphine TACR1;OPRM1;OPRK1 GO:0046887| positive regulation of hormone secretion CREB1;TACR1 9758:[DB01183 DB08059] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08059|Wortmannin PIK3CG;PLK1;PIK3R1;PIK3CA common genes common pathways GO:0043491| protein kinase B signaling cascade CREB1;PIK3CA GO:0006954| inflammatory response PIK3CA;PIK3CG;TLR4 GO:0016032| viral reproduction PIK3R1;CREB1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;PIK3R1 GO:0071168| protein localization to chromatin ESR1;PLK1 GO:0001889| liver development PIK3CA;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PIK3R1;CREB1;TLR4;ESR1 GO:0043066| negative regulation of apoptotic process PLK1;PIK3R1;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;ESR1 GO:0045087| innate immune response TLR4;PIK3CG;PIK3CA GO:0000086| G2/M transition of mitotic cell cycle PLK1;ABCB1 GO:0045671| negative regulation of osteoclast differentiation PIK3R1;TLR4 GO:0007411| axon guidance PIK3R1;CREB1;PIK3CA GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PIK3R1;PIK3CG;PIK3CA;OPRD1;OPRM1 GO:0050821| protein stabilization CREB1;PIK3R1 GO:0006468| protein phosphorylation PIK3CA;PLK1;PIK3CG;CREB1;PIK3R1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;PIK3CG GO:0002376| immune system process TLR4;PIK3CG GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PIK3CA GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;PIK3R1;OPRK1 9759:[DB01183 DB07500] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;TLR4 GO:0006629| lipid metabolic process CYP3A4;PLA2G2E 9760:[DB01183 DB01704] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways GO:0007586| digestion CTRB1;UGT1A1 9761:[DB01183 DB12874] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12874|Quizartinib FLT3 common genes common pathways GO:0042981| regulation of apoptotic process CREB1;ESR1;FLT3 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;FLT3 GO:0031100| organ regeneration UGT1A1;FLT3 GO:0006468| protein phosphorylation FLT3;CREB1 GO:0030154| cell differentiation FLT3;CREB1 9762:[DB01183 DB05750] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05750|AVE-1625 CNR1 common genes common pathways GO:0032496| response to lipopolysaccharide CNR1;OPRM1;TLR4;UGT1A1 GO:0019233| sensory perception of pain CNR1;OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol OPRK1;UGT1A1;CNR1;OPRM1 GO:0043065| positive regulation of apoptotic process CREB1;CNR1 GO:0043278| response to morphine CNR1;OPRM1;OPRK1 GO:0035094| response to nicotine CNR1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR1;OPRK1 GO:0007568| aging CREB1;CNR1 GO:0007613| memory CREB1;CNR1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;CNR1;ESR1;OPRD1;OPRM1 GO:0042220| response to cocaine OPRK1;CNR1;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR1 GO:0007584| response to nutrient CNR1;UGT1A1 9763:[DB01183 DB07127] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07127|{4-[2,2-BIS(5-METHYL-1,2,4-OXADIAZOL-3-YL)-3-PHENYLPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways 9764:[DB01183 DB05394] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05394|Corticorelin DBH common genes common pathways GO:0007613| memory CREB1;DBH GO:0007626| locomotory behavior OPRK1;OPRM1;DBH GO:0008542| visual learning CREB1;DBH GO:0042711| maternal behavior OPRK1;DBH GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DBH GO:0048149| behavioral response to ethanol OPRM1;DBH GO:0007268| synaptic transmission OPRM1;OPRD1;DBH;OPRK1 9765:[DB01183 DB04115] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04115|Berberine BIRC5 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;BIRC5 GO:0006468| protein phosphorylation BIRC5;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;BIRC5;ESR1 GO:0006351| transcription, DNA-dependent CREB1;BIRC5;ESR1 GO:0043066| negative regulation of apoptotic process ALB;BIRC5 GO:0042981| regulation of apoptotic process BIRC5;ESR1;CREB1 9766:[DB01183 DB02660] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02660|Filaminast PDE4B common genes common pathways GO:0007165| signal transduction OPRK1;PDE4B;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE4B;OPRD1;OPRM1 GO:0071222| cellular response to lipopolysaccharide PDE4B;OPRK1;TLR4 GO:0032729| positive regulation of interferon-gamma production PDE4B;TLR4 9767:[DB01183 DB13781] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13781|Xamoterol ADRB1 common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;ADRB1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB1;OPRM1;OPRD1 9768:[DB01183 DB00720] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0006954| inflammatory response TLR4;PTGS2 GO:0016032| viral reproduction SLC25A5;CREB1;SLC25A4;SLC25A6 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;PTGS2 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0050727| regulation of inflammatory response PTGS2;ESR1;TLR4 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0019233| sensory perception of pain OPRK1;OPRD1;PTGS2;OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1;UGT1A1;TLR4 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:1990830| SLC25A5;CREB1 GO:0055085| transmembrane transport SLC25A4;ABCB1;SLC25A5;SLC25A6;SLCO1A2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0098869| PTGS2;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007613| memory PTGS2;CREB1 GO:0006810| transport SLC25A4;ABCB1;SLC25A5 GO:0007568| aging PTGS2;CREB1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 9769:[DB01183 DB00653] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways GO:0006810| transport CACNG1;CACNB1;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration CACNA1C;OPRM1;ESR1 GO:0070588| calcium ion transmembrane transport CACNG1;CACNA1C;CACNA2D1;CACNB2;OPRM1;CACNB1;CACNA1S GO:0055085| transmembrane transport SLCO1A2;CACNA1C;CACNA1S;ABCB1 GO:0006811| ion transport CACNA1C;CACNG1;SLCO1A2;CACNA2D1;CACNB2;CACNB1;CACNA1S GO:1904646| CACNA2D1;CACNB1;TLR4 GO:0007268| synaptic transmission OPRK1;CACNB1;CACNB2;OPRD1;OPRM1 GO:0051924| regulation of calcium ion transport OPRD1;CACNA2D1 9770:[DB01183 DB01147] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB GO:0009267| cellular response to starvation ALB GO:0015711| organic anion transport SLC22A6;SLCO1A2 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC22A6;SLC15A2;SLCO1A2 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0006811| ion transport SLC15A1;SLC15A2;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0007586| digestion UGT1A1;SLC15A1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB 9771:[DB01183 DB02932] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02932|(R)-Bicalutamide AR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;CREB1;TLR4 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;AR GO:0006810| transport ABCB1;AR GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development AR;ESR1 9772:[DB01183 DB00120] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;TH GO:0007613| memory TH;CREB1 GO:0006810| transport ABCB1;SLC7A8 GO:0032355| response to estradiol stimulus TH;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TAT GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;TH GO:0014823| response to activity CREB1;TH GO:0001666| response to hypoxia CREB1;TH GO:0055085| transmembrane transport SLC16A10;SLCO1A2;ABCB1 GO:0042755| eating behavior OPRK1;OPRM1;OPRD1;TH GO:0009636| response to toxin SLC7A8;CES1 GO:0014070| response to organic cyclic compound TH;UGT1A1;TAT GO:0070848| response to growth factor stimulus OPRM1;TH GO:0007626| locomotory behavior OPRK1;OPRM1;TH GO:0008152| metabolic process UGT1A1;PAH;CES1 GO:0045471| response to ethanol TH;OPRM1;OPRK1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;TH GO:0035094| response to nicotine TH;CREB1 GO:0055114| oxidation-reduction process TH;CYP3A4;CYP2C8;PAH GO:0042493| response to drug ABCB1;CREB1;UGT1A1;TH 9773:[DB01183 DB07677] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 9774:[DB01183 DB07592] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07592|(2R)-3-Methyl-1-phenyl-2-butanyl [(2S)-1-oxo-2-hexanyl]carbamate CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 9775:[DB01183 DB04117] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04117|4-(N,N-Dimethylamino)Cinnamoyl-Coa ECHS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ECHS1 GO:0008152| metabolic process CES1;ECHS1;UGT1A1 9776:[DB01183 DB02758] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;TLR4 GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 9777:[DB01183 DB07509] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance PPARG;CREB1;UGT1A1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0030855| epithelial cell differentiation CES1;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction OPRK1;CREB1;PPARG;TLR4;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRM1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0042493| response to drug CREB1;PPARG;UGT1A1;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;CREB1;TLR4 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response PPARG;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;CREB1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 9778:[DB01183 DB01647] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01647|Daxalipram PDE4B common genes common pathways GO:0032729| positive regulation of interferon-gamma production TLR4;PDE4B GO:0071222| cellular response to lipopolysaccharide PDE4B;OPRK1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE4B;OPRD1;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;PDE4B;TLR4;CREB1 9779:[DB01183 DB00869] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0043627| response to estrogen stimulus CA2;OPRK1;ESR1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0010033| response to organic substance CA2;UGT1A1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0045471| response to ethanol OPRM1;CA3;UGT1A1;OPRK1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP3A4 GO:0045672| positive regulation of osteoclast differentiation CREB1;CA2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 9780:[DB01183 DB02589] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02589|Se-Ethyl-Isoselenourea NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 9781:[DB01183 DB04276] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04276|N-[N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-Butyl]-Guanidine CAPN1 common genes common pathways 9782:[DB01183 DB03849] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4;PDE4B GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PDE4B;PDE4D GO:0007568| aging PDE4D;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE4B;PDE4D;OPRD1;OPRM1 GO:0007165| signal transduction PDE4B;OPRK1;CREB1;TLR4;OPRM1;PDE4D;OPRD1;ESR1 9783:[DB01183 DB07701] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways 9784:[DB01183 DB07561] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;UGT1A1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;DHODH GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHODH GO:0007595| lactation DHODH;CREB1 GO:0043065| positive regulation of apoptotic process CREB1;DHODH GO:0042594| response to starvation DHODH;UGT1A1 9785:[DB01183 DB00147] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00147|Pyridoxal PDXK common genes common pathways 9786:[DB01183 DB01541] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01541|Boldenone AR common genes common pathways GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;CREB1;TLR4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0007165| signal transduction AR;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0006810| transport ABCB1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0016579| protein deubiquitination AR;ESR1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development ESR1;AR 9787:[DB01183 DB00998] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0045471| response to ethanol UGT1A1;HTR1B;OPRK1;OPRM1 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;HTR1B;ABCB1 GO:0007268| synaptic transmission OPRK1;HTR1B;HTR1D;OPRD1;OPRM1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0007165| signal transduction OPRM1;HTR1D;OPRD1;ESR1;CREB1;TLR4;HTR1B;OPRK1 GO:0007610| behavior OPRK1;HTR1B GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway HTR1B;OPRK1;OPRD1;HTR1D;OPRM1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;HTR1D;OPRM1;HTR1B;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR1B;OPRM1;OPRD1;HTR1D GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0009636| response to toxin HTR1D;CES1 GO:0042220| response to cocaine OPRM1;HTR1B;OPRK1 9788:[DB01183 DB00133] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC16A10 GO:0014070| response to organic cyclic compound SRR;UGT1A1 GO:0007568| aging CREB1;SRR GO:0051384| response to glucocorticoid stimulus AGXT;UGT1A1 GO:0043278| response to morphine OPRM1;OPRK1;SRR GO:0055114| oxidation-reduction process CBS;CYP2C8;CYP3A4 GO:0042493| response to drug CREB1;UGT1A1;SRR;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;SARS;CREB1 GO:0006629| lipid metabolic process CYP3A4;SPTLC2;SPTLC1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;SARS GO:0008152| metabolic process UGT1A1;CBS;SRR;SPTLC2;CES1 GO:0006351| transcription, DNA-dependent SARS;ESR1;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;SRR;TLR4;UGT1A1 9789:[DB01183 DB05422] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05422|OPC-14523 SLC6A4 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLC6A4;ABCB1 GO:0009636| response to toxin SLC6A4;CES1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0010033| response to organic substance SLC6A4;UGT1A1;CREB1 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0007613| memory SLC6A4;CREB1 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;SLC6A4 GO:0007623| circadian rhythm CREB1;SLC6A4 9790:[DB01183 DB13749] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0031100| organ regeneration PFKFB1;UGT1A1 GO:0007165| signal transduction ADCY1;OPRK1;CREB1;GUCY1A2;TLR4;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADCY1;OPRK1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PFKFB1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;OPRM1;ESR1 GO:0006468| protein phosphorylation CREB1;ABL1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY1;OPRK1;OPRM1;OPRD1 GO:0048511| rhythmic process ADCY1;CREB1 GO:0007409| axonogenesis ADCY1;CREB1 GO:0006811| ion transport ATP1A1;SLCO1A2 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ABL1;OPRM1 GO:0032868| response to insulin stimulus PFKFB1;OPRK1 GO:0002322| B cell proliferation involved in immune response ABL1;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ABL1 GO:0043065| positive regulation of apoptotic process CREB1;ABL1 GO:0008152| metabolic process CES1;PFKFB1;UGT1A1 GO:0045087| innate immune response TLR4;ABL1 GO:0033762| response to glucagon stimulus CREB1;PFKFB1 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:0042594| response to starvation UGT1A1;PFKFB1 GO:0007623| circadian rhythm ADCY1;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;ABL1 GO:0042752| regulation of circadian rhythm CREB1;ADCY1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ABL1;ESR1 GO:0042493| response to drug ADCY1;ABCB1;UGT1A1;CREB1;ATP1A1 9791:[DB01183 DB12089] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12089|Lorvotuzumab mertansine CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 9792:[DB01183 DB07173] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 9793:[DB01183 DB02890] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways GO:0007595| lactation CREB1;UMPS GO:0008152| metabolic process CES1;UGT1A1;UMPS 9794:[DB01183 DB00066] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00066|Follitropin FSHR common genes common pathways GO:0008584| male gonad development ESR1;FSHR GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;FSHR;OPRM1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;FSHR;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;FSHR;OPRK1 9795:[DB01183 DB01873] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes CYP3A4 common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBA4A;TUBA1A;TUBB;TUBB4B;ABCB1;TUBB4A GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007411| axon guidance TUBB3;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0002576| platelet degranulation ALB;TUBA4A 9796:[DB01183 DB08809] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08809|Dichloroacetic Acid PDK1;GSTZ1 common genes common pathways GO:0008152| metabolic process UGT1A1;GSTZ1;CES1 GO:0006468| protein phosphorylation PDK1;CREB1 GO:0098869| GSTZ1;ALB 9797:[DB01183 DB11595] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11595|Atezolizumab CD274 common genes common pathways GO:0032689| negative regulation of interferon-gamma production TLR4;CD274 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CD274;CREB1 GO:0006955| immune response OPRD1;OPRK1;TLR4;CD274 9798:[DB01183 DB01751] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0044267| cellular protein metabolic process ALB;TTR 9799:[DB01183 DB02774] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02774|1,3-Propandiol ARF1 common genes common pathways 9800:[DB01183 DB04856] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes CYP3A4 common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;CCKAR;OPRM1;OPRD1;ESR1 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0007586| digestion UGT1A1;CCKAR GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C8;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A5;CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0007204| elevation of cytosolic calcium ion concentration CCKAR;OPRM1;ESR1 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP2C9;UGT1A1;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CCKAR;OPRK1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;CCKAR;TLR4;CREB1;OPRK1 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0032870| cellular response to hormone stimulus CCKAR;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8;CYP2C9 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A5;CYP2C8 GO:0007409| axonogenesis CREB1;CCKAR GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0007584| response to nutrient CCKAR;UGT1A1 GO:0042359| vitamin D metabolic process CYP3A4 9801:[DB01183 DB01582] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01582|Sulfamethazine ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB 9802:[DB01183 DB00397] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007165| signal transduction DRD1;OPRM1;OPRD1;ADRA2C;ESR1;ADRB2;ADRA2B;ADRB1;ADRA2A;OPRK1;CREB1;TLR4 GO:0014002| astrocyte development TLR4;DRD1 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;ADRA2A;OPRK1;OPRM1;OPRD1;ADRA2C;ADRA2B;ADRB2;DRD1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007613| memory DRD1;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A;OPRK1 GO:1904646| TLR4;ADRB2 GO:0010628| positive regulation of gene expression TLR4;DRD1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRD1;OPRM1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1;OPRK1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0042220| response to cocaine OPRM1;DRD1;OPRK1 GO:0007626| locomotory behavior OPRK1;OPRM1;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0048148| behavioral response to cocaine OPRK1;DRD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD1 GO:0042711| maternal behavior OPRK1;DRD1 GO:0008542| visual learning DRD1;CREB1 GO:0042493| response to drug DRD1;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA 9803:[DB01183 DB03944] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 9804:[DB01183 DB03413] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways GO:0014070| response to organic cyclic compound DUT;UGT1A1 GO:0001889| liver development UGT1A1;DUT 9805:[DB01183 DB04466] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04466|SR12813 NR1I2 common genes common pathways GO:0006805| xenobiotic metabolic process NR1I2;CYP2C8;CYP3A4;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;NR1I2;TLR4 GO:0006351| transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I2;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8 GO:0007165| signal transduction CREB1;NR1I2;TLR4;OPRK1;ESR1;OPRM1;OPRD1 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0008202| steroid metabolic process UGT1A1;NR1I2;CYP2C8;CYP3A4 GO:0010628| positive regulation of gene expression NR1I2;TLR4 9806:[DB01183 DB07629] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07629|N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways 9807:[DB01183 DB02115] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02115|Daidzin ALDH2;ABCG2 common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;ALDH2 GO:0055114| oxidation-reduction process CYP3A4;ALDH2;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0055085| transmembrane transport SLCO1A2;ABCG2;ABCB1 9808:[DB01183 DB09310] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 9809:[DB01183 DB03706] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03706|1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane GSTM4 common genes common pathways GO:0008152| metabolic process UGT1A1;GSTM4;CES1 9810:[DB01183 DB08047] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08047|4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol ESR1;NCOA2 common genes ESR1 common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0007623| circadian rhythm NCOA2;CREB1 GO:0006351| transcription, DNA-dependent NCOA2;CREB1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0060065| uterus development ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TLR4;CREB1;ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0015721| bile acid and bile salt transport NCOA2;ALB;SLCO1A2 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1 9811:[DB01183 DB05012] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC6A2 GO:0042493| response to drug ABCB1;CREB1;SLC6A2;UGT1A1 GO:0007268| synaptic transmission SLC6A2;OPRK1;OPRD1;OPRM1 9812:[DB01183 DB07681] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07681|DODECANESULFONATE ION BCHE common genes common pathways GO:0042493| response to drug CREB1;BCHE;UGT1A1;ABCB1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 9813:[DB01183 DB00728] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes SLCO1A2 common pathways GO:0006811| ion transport SLCO1A2;CHRNA2;SLC22A1;HTR3A GO:0042220| response to cocaine OPRM1;HTR3A;OPRK1 GO:0055085| transmembrane transport SLCO1A2;SLC22A1;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM2;OPRK1 GO:0071363| cellular response to growth factor stimulus CREB1;HTR3A;OPRD1 GO:0015711| organic anion transport SLCO1A2;SLC22A1 GO:0007165| signal transduction HTR3A;OPRK1;CREB1;TLR4;CHRNA2;OPRM1;OPRD1;ESR1;CHRM2 GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;HTR3A GO:0035094| response to nicotine CREB1;CHRNA2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA2 GO:0045471| response to ethanol OPRM1;HTR3A;OPRK1;UGT1A1 9814:[DB01183 DB02636] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2E GO:0006954| inflammatory response PLA2G2E;TLR4 9815:[DB01183 DB03017] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03017|Lauric Acid ADH5;fabB;GM2A;fabH;HNF4A;PLA2G2A;VLDLR;GLTP;fabF;LTF;tonB;C8G;PLA2G2D;LY96;TLR4;PPARA;ALB common genes ALB;TLR4 common pathways GO:0032720| negative regulation of tumor necrosis factor production TLR4 GO:0006898| receptor-mediated endocytosis ALB;VLDLR GO:0032689| negative regulation of interferon-gamma production TLR4 GO:0032757| positive regulation of interleukin-8 production TLR4 GO:0002376| immune system process TLR4;LTF;LY96;C8G GO:0034128| negative regulation of MyD88-independent toll-like receptor signaling pathway LY96;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;LY96 GO:0032715| negative regulation of interleukin-6 production TLR4 GO:0060907| positive regulation of macrophage cytokine production TLR4 GO:0098869| ALB GO:0016046| detection of fungus TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0045359| positive regulation of interferon-beta biosynthetic process TLR4 GO:0032728| positive regulation of interferon-beta production TLR4 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;VLDLR;OPRM1;OPRD1 GO:0032722| positive regulation of chemokine production TLR4 GO:0043032| positive regulation of macrophage activation TLR4 GO:0035666| TRIF-dependent toll-like receptor signaling pathway TLR4;LY96 GO:0032732| positive regulation of interleukin-1 production TLR4 GO:0014002| astrocyte development TLR4 GO:0051659| maintenance of mitochondrion location ALB GO:0032735| positive regulation of interleukin-12 production TLR4 GO:0008202| steroid metabolic process CYP3A4;VLDLR;CYP2C8;UGT1A1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0050729| positive regulation of inflammatory response TLR4;PLA2G2A GO:0009267| cellular response to starvation ALB GO:0007613| memory CREB1;VLDLR GO:0043069| negative regulation of programmed cell death ALB GO:0002224| toll-like receptor signaling pathway LY96;TLR4 GO:1900017| TLR4 GO:0032700| negative regulation of interleukin-17 production TLR4 GO:0032497| detection of lipopolysaccharide LY96;TLR4 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:1903428| TLR4 GO:0070430| positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway TLR4 GO:0030890| positive regulation of B cell proliferation TLR4 GO:0001666| response to hypoxia CREB1;PPARA GO:1904646| TLR4 GO:0010628| positive regulation of gene expression TLR4 GO:0048511| rhythmic process CREB1;PPARA GO:0007411| axon guidance VLDLR;CREB1 GO:0008285| negative regulation of cell proliferation HNF4A;OPRM1 GO:1903223| TLR4 GO:0034142| toll-like receptor 4 signaling pathway TLR4;LY96 GO:0006811| ion transport SLCO1A2;LTF GO:0034375| high-density lipoprotein particle remodeling ALB GO:0060729| intestinal epithelial structure maintenance TLR4 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;PLA2G2A;OPRM1 GO:0045084| positive regulation of interleukin-12 biosynthetic process TLR4 GO:0042116| macrophage activation TLR4 GO:0045671| negative regulation of osteoclast differentiation TLR4 GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0044267| cellular protein metabolic process ALB;LTF GO:0002322| B cell proliferation involved in immune response TLR4 GO:0070434| positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway TLR4 GO:0001895| retina homeostasis ALB;LTF GO:0000187| activation of MAPK activity TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;LY96 GO:0050829| defense response to Gram-negative bacterium LTF;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;HNF4A;PPARA;ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0002537| nitric oxide production involved in inflammatory response TLR4 GO:0002576| platelet degranulation ALB GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR4;LY96 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;LY96 GO:0043066| negative regulation of apoptotic process ALB;LTF GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;HNF4A;CYP2C8 GO:0070266| necroptosis LY96;TLR4 GO:0045087| innate immune response LTF;LY96;C8G;TLR4 GO:0032733| positive regulation of interleukin-10 production TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VLDLR;ESR1;PPARA GO:0042088| T-helper 1 type immune response TLR4 GO:0071260| cellular response to mechanical stimulus TLR4 GO:0032707| negative regulation of interleukin-23 production TLR4 GO:0010572| positive regulation of platelet activation TLR4 GO:0006629| lipid metabolic process VLDLR;PLA2G2D;CYP3A4;PPARA;HNF4A;PLA2G2A;GM2A GO:0032496| response to lipopolysaccharide OPRM1;LY96;TLR4;UGT1A1;ADH5 GO:0032727| positive regulation of interferon-alpha production TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;HNF4A GO:0042060| wound healing PPARA;OPRM1 GO:0071223| cellular response to lipoteichoic acid TLR4 GO:0002756| MyD88-independent toll-like receptor signaling pathway LY96;TLR4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0032729| positive regulation of interferon-gamma production TLR4 GO:0050671| positive regulation of lymphocyte proliferation TLR4 GO:1900227| TLR4 GO:0045348| positive regulation of MHC class II biosynthetic process TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;TLR4 GO:0097190| apoptotic signaling pathway LY96;TLR4 GO:0032874| positive regulation of stress-activated MAPK cascade TLR4 GO:0006351| transcription, DNA-dependent LTF;ESR1;PPARA;HNF4A;CREB1 GO:0046330| positive regulation of JNK cascade TLR4 GO:0043401| steroid hormone mediated signaling pathway HNF4A;PPARA;ESR1 GO:0006954| inflammatory response LY96;PLA2G2D;TLR4 GO:0032609| interferon-gamma production TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;LTF GO:0002730| regulation of dendritic cell cytokine production TLR4 GO:0050707| regulation of cytokine secretion TLR4 GO:0007252| I-kappaB phosphorylation TLR4 GO:0006955| immune response OPRD1;OPRK1;TLR4 GO:0032760| positive regulation of tumor necrosis factor production LY96;TLR4 GO:0042752| regulation of circadian rhythm CREB1;PPARA GO:0042535| positive regulation of tumor necrosis factor biosynthetic process TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter HNF4A;PPARA;ESR1 GO:0050702| interleukin-1 beta secretion TLR4 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4 GO:0006355| regulation of transcription, DNA-dependent HNF4A;CREB1;LTF;ESR1;PPARA GO:0140052| TLR4 GO:0045893| positive regulation of transcription, DNA-dependent HNF4A;CREB1;PPARA;ESR1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4 GO:0002218| activation of innate immune response TLR4 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process ADH5;CYP2C8;CYP3A4 GO:0042742| defense response to bacterium TLR4;LTF GO:0009617| response to bacterium TLR4 GO:1901215| CREB1;PPARA 9816:[DB01183 DB04436] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04436|3-Fluorotyrosine SOD2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD2;CYP2C8 GO:0006357| regulation of transcription from RNA polymerase II promoter SOD2;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;SOD2 9817:[DB01183 DB13876] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13876|Brofaromine MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8 9818:[DB01183 DB04374] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04374|4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HAO1;CYP2C8 9819:[DB01183 DB09047] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways GO:0048511| rhythmic process TOP2A;CREB1 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;TOP2A;CREB1 9820:[DB01183 DB01666] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter FST;ESR1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;FST 9821:[DB01183 DB04121] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways 9822:[DB01183 DB08631] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08631|N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 9823:[DB01183 DB06249] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06249|Arzoxifene ESR1;ESR2 common genes ESR1 common pathways GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction CREB1;TLR4;ESR2;OPRK1;ESR1;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR2;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TLR4;CREB1;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 9824:[DB01183 DB04941] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04941|Crofelemer CFTR;ANO1 common genes common pathways GO:0016579| protein deubiquitination ESR1;CFTR GO:0055085| transmembrane transport SLCO1A2;ABCB1;CFTR GO:0006811| ion transport SLCO1A2;ANO1;CFTR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1;ANO1 GO:0006695| cholesterol biosynthetic process CFTR;CES1 9825:[DB01183 DB06133] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06133|Dimethylcurcumin AR common genes common pathways GO:0010628| positive regulation of gene expression TLR4;AR GO:0008584| male gonad development ESR1;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0016579| protein deubiquitination ESR1;AR GO:0006810| transport ABCB1;AR GO:0007165| signal transduction AR;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006351| transcription, DNA-dependent CREB1;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;CREB1;TLR4 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 9826:[DB01183 DB07193] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9827:[DB01183 DB07754] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways GO:0008152| metabolic process CES1;FOLH1;UGT1A1 9828:[DB01183 DB12379] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0032094| response to food CYP1A1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;AHR GO:0042493| response to drug UGT1A1;CREB1;CYP1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AHR;CREB1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2C8 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;ESR1 GO:0032496| response to lipopolysaccharide CYP1A1;TLR4;UGT1A1;OPRM1 GO:0006351| transcription, DNA-dependent ESR1;AHR;CREB1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;AHR;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;AHR GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0009636| response to toxin AHR;CYP1A1;CES1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1;AHR GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1;CREB1 GO:0048511| rhythmic process AHR;CREB1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP1A1;CYP2C8 GO:0007568| aging CREB1;CYP1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A1;CYP3A4 GO:0097267| CYP1A1;CYP2C8 9829:[DB01183 DB01576] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0009636| response to toxin SLC18A2;CES1 GO:0042220| response to cocaine OPRK1;SLC6A3;OPRM1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A2;SLCO1A2;SLC18A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;OPRM1 GO:0007165| signal transduction OPRK1;ADRA1A;TLR4;CREB1;TAAR1;ADRA1B;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;OPRK1;TAAR1;ADRA1B;OPRM1;OPRD1 GO:0006810| transport ABCB1;SLC6A2 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging CREB1;SLC6A3;ADRA1A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;OPRM1;ESR1;ADRA1B GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007595| lactation CREB1;SLC6A3 GO:0042493| response to drug SLC6A2;UGT1A1;CREB1;ABCB1;ADRA1A;SLC6A3 GO:0007268| synaptic transmission OPRM1;OPRD1;SLC18A2;SLC6A2;OPRK1 GO:0007626| locomotory behavior SLC6A3;OPRK1;OPRM1;SLC18A2 GO:0045471| response to ethanol UGT1A1;OPRK1;SLC6A3;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;ADRA1B;ADRA1A;OPRK1 9830:[DB01183 DB13999] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0042220| response to cocaine OPRK1;HSPA5;OPRM1 GO:0044267| cellular protein metabolic process ALB;F2;PROC GO:0010628| positive regulation of gene expression TLR4;CALR GO:1904646| TLR4;LRP1 GO:0010033| response to organic substance UGT1A1;CALR;CREB1 GO:0032355| response to estradiol stimulus CALR;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;F2;OPRD1;OPRM1 GO:0050821| protein stabilization CREB1;CALR GO:0007568| aging CREB1;LRP1;CANX GO:0006898| receptor-mediated endocytosis ALB;CALR;LRP1;ASGR2 GO:0042493| response to drug ABCB1;CALR;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CALR;CREB1 GO:0055114| oxidation-reduction process CYP3A4;PHYH;CYP2C8 GO:0043687| post-translational protein modification PROC;ALB GO:0006953| acute-phase response UGT1A1;F2 GO:0001889| liver development UGT1A1;PROC GO:0043066| negative regulation of apoptotic process HSPA5;ALB;PROC GO:0002576| platelet degranulation VWF;ALB GO:0009314| response to radiation OPRM1;OPRK1;HSPA5 GO:0006629| lipid metabolic process CYP3A4;LRP1 GO:1990090| CREB1;HSPA5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1 GO:0042981| regulation of apoptotic process CREB1;CALR;ESR1 9831:[DB01183 DB07326] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07326|6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR GO:0016032| viral reproduction CREB1;KDR GO:0010629| negative regulation of gene expression CREB1;KDR;OPRD1;ESR1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0006468| protein phosphorylation CREB1;KDR GO:0030154| cell differentiation KDR;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;TLR4 9832:[DB01183 DB06205] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes ALB common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation TGFB1;OPRD1 GO:0006898| receptor-mediated endocytosis ALB GO:0031100| organ regeneration UGT1A1;TGFB1 GO:1903799| ESR1;TGFB1 GO:0098869| ALB GO:0006468| protein phosphorylation TGFB1;CREB1 GO:0007568| aging TGFB1;CREB1 GO:0032700| negative regulation of interleukin-17 production TLR4;TGFB1 GO:0043069| negative regulation of programmed cell death ALB GO:1990314| CREB1;TGFB1 GO:0032355| response to estradiol stimulus ESR1;TGFB1 GO:0071363| cellular response to growth factor stimulus CREB1;TGFB1;OPRD1 GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0008285| negative regulation of cell proliferation OPRM1;TGFB1 GO:0010033| response to organic substance TGFB1;UGT1A1;CREB1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0001666| response to hypoxia TGFB1;CREB1 GO:0010628| positive regulation of gene expression TLR4;TGFB1 GO:0048146| positive regulation of fibroblast proliferation TGFB1;ESR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TGFB1;OPRM1;TLR4 GO:0001895| retina homeostasis ALB GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;TGFB1 GO:0044267| cellular protein metabolic process ALB GO:0030879| mammary gland development TGFB1;CREB1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound UGT1A1;TGFB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TGFB1 GO:0042981| regulation of apoptotic process ESR1;TGFB1;CREB1 GO:0071260| cellular response to mechanical stimulus TGFB1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;TGFB1 GO:0002576| platelet degranulation TGFB1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;TGFB1 GO:0009314| response to radiation OPRM1;TGFB1;OPRK1 GO:0071560| cellular response to transforming growth factor beta stimulus TGFB1;CREB1 GO:0043066| negative regulation of apoptotic process ALB GO:0031663| lipopolysaccharide-mediated signaling pathway TGFB1;TLR4 GO:0000060| protein import into nucleus, translocation TGFB1;OPRD1 GO:0042060| wound healing OPRM1;TGFB1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0051092| positive regulation of NF-kappaB transcription factor activity TGFB1;TLR4 GO:0006954| inflammatory response TGFB1;TLR4 GO:0043491| protein kinase B signaling cascade CREB1;TGFB1 GO:0043687| post-translational protein modification ALB GO:0010629| negative regulation of gene expression CREB1;ESR1;TGFB1;OPRD1 GO:0042493| response to drug TGFB1;ABCB1;CREB1;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;TGFB1 9833:[DB01183 DB11450] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;CYP1A2;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 9834:[DB01183 DB01838] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR GO:0006810| transport TTR;ABCB1 9835:[DB01183 DB08020] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes ESR1 common pathways GO:0007165| signal transduction CREB1;TLR4;ESR2;OPRK1;OPRM1;OPRD1;ESR1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;ESR2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;CREB1;TLR4;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0001547| antral ovarian follicle growth ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 9836:[DB01183 DB02236] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways GO:0010033| response to organic substance UGT1A1;GART;CREB1 GO:0008152| metabolic process UGT1A1;GART;CES1 9837:[DB01183 DB01185] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes ESR1 common pathways GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0043066| negative regulation of apoptotic process ALB;PRLR GO:0060065| uterus development ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;AR;NR3C1;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development PRLR;ESR1;AR GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1;NR3C1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1;AR GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0007595| lactation PRLR;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0032094| response to food HSD11B2;OPRM1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;NR3C1;CREB1 GO:0042493| response to drug CREB1;UGT1A1;HSD11B2;ABCB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0055114| oxidation-reduction process CYP2C8;HSD11B2;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRM1;OPRD1;NR3C1;ESR1;AR;CREB1;TLR4;OPRK1 GO:0048545| response to steroid hormone stimulus HSD11B2;UGT1A1 GO:0051384| response to glucocorticoid stimulus HSD11B2;UGT1A1 GO:0032355| response to estradiol stimulus ESR1 GO:0006810| transport ABCB1;AR GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0001666| response to hypoxia HSD11B2;CREB1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development AR;ESR1 GO:0016579| protein deubiquitination ESR1;AR GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0032868| response to insulin stimulus OPRK1;HSD11B2 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 9838:[DB01183 DB08320] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08320|DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE ESR1;NCOA2 common genes ESR1 common pathways GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;OPRK1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;CREB1;TLR4;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060065| uterus development ESR1 9839:[DB01183 DB01756] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 9840:[DB01183 DB08022] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08022|(2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile PIM1 common genes common pathways GO:0006468| protein phosphorylation PIM1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 GO:0043066| negative regulation of apoptotic process ALB;PIM1 9841:[DB01183 DB07512] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07512|7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE MAOB common genes common pathways GO:0009636| response to toxin CES1;MAOB GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;MAOB GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1;MAOB GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MAOB;OPRM1 9842:[DB01183 DB06926] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;PPARG;TLR4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0042493| response to drug ABCB1;PPARG;CREB1;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;CREB1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 9843:[DB01183 DB07318] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways GO:0001666| response to hypoxia NOS2;CREB1 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;NOS2;UGT1A1 GO:0007623| circadian rhythm CREB1;NOS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS2 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0009617| response to bacterium TLR4;NOS2 GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 9844:[DB01183 DB08170] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08170|(1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE MMP7 common genes common pathways GO:0044849| OPRK1;MMP7;OPRM1 GO:0007568| aging CREB1;MMP7 GO:0071260| cellular response to mechanical stimulus MMP7;TLR4 9845:[DB01183 DB08180] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08180|2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE FNTA;PGGT1B common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CREB1 9846:[DB01183 DB08087] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0006355| regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;TLR4;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development AR;ESR1 GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;AR GO:0006810| transport AR;ABCB1 9847:[DB01183 DB00146] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP27B1;CYP24A1 GO:0060745| mammary gland branching involved in pregnancy ESR1;VDR GO:0006355| regulation of transcription, DNA-dependent ESR1;VDR;CREB1 GO:0007595| lactation CREB1;VDR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;VDR GO:0006351| transcription, DNA-dependent ESR1;VDR;CREB1 GO:0043401| steroid hormone mediated signaling pathway VDR;ESR1 GO:0032496| response to lipopolysaccharide OPRM1;CYP27B1;TLR4;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;VDR;ESR1 GO:0036378| CYP27B1;CYP3A4 GO:0043627| response to estrogen stimulus CYP27B1;ESR1;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;CYP27B1;VDR GO:0010628| positive regulation of gene expression VDR;TLR4 GO:0042359| vitamin D metabolic process CYP24A1;CYP3A4;CYP27B1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;VDR 9848:[DB01183 DB03065] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03065|7-Nitroindazole-2-Carboxamidine NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 9849:[DB01183 DB06421] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TOP2A;CREB1;TLR4 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0007409| axonogenesis TOP2B;CREB1 GO:0048511| rhythmic process CREB1;TOP2A 9850:[DB01183 DB13133] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0007584| response to nutrient UGT1A1;COL1A1 GO:0009636| response to toxin CES1;ADAMTS13 GO:0048545| response to steroid hormone stimulus UGT1A1;COL1A1 GO:0032355| response to estradiol stimulus ESR1;COL1A1 GO:0006953| acute-phase response F8;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;F8;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent COL1A1;CREB1;ESR1 GO:0042493| response to drug ABCB1;COL1A1;UGT1A1;CREB1 GO:0071260| cellular response to mechanical stimulus COL1A1;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus COL1A1;CREB1 GO:0002576| platelet degranulation F8;ALB GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ADAMTS13 GO:0042060| wound healing OPRM1;COL1A1 9851:[DB01183 DB07977] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0042594| response to starvation UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process CREB1;DHODH GO:0055114| oxidation-reduction process DHODH;CYP3A4;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;DHODH GO:0007595| lactation DHODH;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;DHODH 9852:[DB01183 DB00233] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;ESR1;TLR4;CREB1 GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0043066| negative regulation of apoptotic process ALB;MPO;PTGS2 GO:0045087| innate immune response TLR4;CHUK GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PLA2G2E GO:0032496| response to lipopolysaccharide CHUK;MPO;PTGS2;OPRM1;UGT1A1;TLR4 GO:0002756| MyD88-independent toll-like receptor signaling pathway CHUK;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CHUK;TLR4 GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRM1;OPRK1 GO:0006954| inflammatory response TLR4;PLA2G2E;PTGS2;CHUK;ALOX5 GO:0051092| positive regulation of NF-kappaB transcription factor activity CHUK;TLR4 GO:0007252| I-kappaB phosphorylation TLR4;CHUK GO:0006955| immune response TLR4;OPRK1;OPRD1;CHUK GO:0042493| response to drug CREB1;UGT1A1;ABCB1;PTGS2;CHUK GO:0045893| positive regulation of transcription, DNA-dependent CREB1;CHUK;ESR1 GO:0032094| response to food MPO;OPRM1 GO:0043491| protein kinase B signaling cascade CREB1;CHUK GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2;ALOX5;MPO GO:0042742| defense response to bacterium MPO;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade CHUK;TLR4 GO:0098869| PTGS2;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0035666| TRIF-dependent toll-like receptor signaling pathway CHUK;TLR4 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0006468| protein phosphorylation CREB1;CHUK GO:0007613| memory CREB1;PTGS2 GO:0007568| aging CREB1;MPO;PTGS2 GO:0010033| response to organic substance CREB1;UGT1A1;CHUK;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0009636| response to toxin CES1;CHUK GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 9853:[DB01183 DB03183] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4 GO:0071222| cellular response to lipopolysaccharide PDE4D;OPRK1;TLR4 GO:0007568| aging CREB1;PDE4D GO:0007186| G-protein coupled receptor signaling pathway OPRM1;PDE4D;OPRD1;OPRK1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;PDE4D;ESR1 9854:[DB01183 DB11606] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11606|Susoctocog alfa VWF common genes common pathways GO:0002576| platelet degranulation ALB;VWF 9855:[DB01183 DB05155] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05155|CR665 OPRK1 common genes OPRK1 common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:1901381| OPRK1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1 GO:0044849| OPRM1;OPRK1 GO:1990708| OPRK1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0007610| behavior OPRK1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0048148| behavioral response to cocaine OPRK1 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1 GO:0009314| response to radiation OPRM1;OPRK1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1 GO:1900745| OPRK1 GO:1903715| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1 GO:0051607| defense response to virus OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:0006955| immune response OPRD1;OPRK1;TLR4 GO:0042711| maternal behavior OPRK1 GO:0007600| sensory perception OPRK1;OPRM1 GO:0043278| response to morphine OPRK1;OPRM1 GO:1903937| OPRK1 9856:[DB01183 DB00585] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00585|Nizatidine HRH2;BCHE;ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug UGT1A1;BCHE;CREB1;ABCB1 GO:0008542| visual learning CREB1;HRH2 GO:0006955| immune response TLR4;OPRK1;HRH2;OPRD1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0007613| memory HRH2;CREB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;HRH2 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;HRH2;OPRM1;OPRD1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HRH2;OPRD1;OPRM1 9857:[DB01183 DB00561] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;KCNK3 GO:0042493| response to drug CREB1;UGT1A1;KCNK3;ABCB1 GO:0071294| cellular response to zinc ion KCNK3;CREB1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;KCNK3 GO:0006811| ion transport KCNK9;SLCO1A2;KCNK3 GO:0071456| cellular response to hypoxia KCNK3;OPRD1 9858:[DB01183 DB02144] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways GO:0007409| axonogenesis CREB1;PITPNA GO:0006629| lipid metabolic process PITPNA;CYP3A4 9859:[DB01183 DB07227] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07227|4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE FNTA;FNTB;PGGT1B common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FNTA 9860:[DB01183 DB12598] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12598|Nafamostat F2;F10;F12;PRSS1;KLK1;ICAM1;SLC22A1;SLC22A2 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;ICAM1;TLR4;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;ICAM1;OPRK1 GO:0071222| cellular response to lipopolysaccharide TLR4;ICAM1;OPRK1 GO:0007586| digestion PRSS1;UGT1A1 GO:0045087| innate immune response F12;TLR4 GO:0042493| response to drug ABCB1;UGT1A1;ICAM1;CREB1 GO:0016032| viral reproduction ICAM1;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;ICAM1 GO:0006953| acute-phase response F2;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway F2;OPRK1;OPRM1;OPRD1 GO:0071456| cellular response to hypoxia ICAM1;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ICAM1;ESR1;OPRM1 GO:0015711| organic anion transport SLCO1A2;SLC22A2;SLC22A1 GO:0014070| response to organic cyclic compound UGT1A1;ICAM1 GO:0006811| ion transport SLCO1A2;SLC22A2;SLC22A1 GO:0044267| cellular protein metabolic process F2;ALB GO:0055085| transmembrane transport SLCO1A2;SLC22A1;ABCB1;SLC22A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ICAM1;TLR4 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ICAM1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0032868| response to insulin stimulus ICAM1;OPRK1 GO:0001666| response to hypoxia ICAM1;CREB1 GO:1990830| CREB1;ICAM1 9861:[DB01183 DB02955] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02955|Ricinoleic Acid CNR1;CNR2;TRPV1 common genes common pathways GO:0006811| ion transport TRPV1;SLCO1A2 GO:0042220| response to cocaine CNR1;OPRM1;OPRK1 GO:0055085| transmembrane transport TRPV1;ABCB1;SLCO1A2 GO:0007584| response to nutrient CNR1;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;OPRM1;CNR2 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;CNR1;OPRK1 GO:0071363| cellular response to growth factor stimulus TRPV1;CREB1;OPRD1 GO:0006810| transport ABCB1;TRPV1 GO:0007568| aging CNR1;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;TRPV1 GO:0007613| memory CREB1;CNR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TLR4;OPRM1;ESR1 GO:0070588| calcium ion transmembrane transport TRPV1;OPRM1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;CNR1;ESR1;TLR4;CREB1;OPRK1 GO:0006955| immune response OPRK1;TLR4;OPRD1;CNR2 GO:0006954| inflammatory response CNR2;TRPV1;TLR4 GO:0035094| response to nicotine CREB1;CNR1 GO:0043278| response to morphine CNR1;OPRM1;OPRK1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;OPRM1;TLR4;UGT1A1 GO:0019233| sensory perception of pain CNR1;OPRD1;OPRM1;CNR2;OPRK1;TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;OPRM1 GO:0045471| response to ethanol OPRM1;CNR1;OPRK1;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;TRPV1;CNR1 GO:0006629| lipid metabolic process TRPV1;CYP3A4 GO:1990090| CREB1;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;ESR1 9862:[DB01183 DB02553] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GSR;CYP2C8 GO:0098869| GSR;ALB 9863:[DB01183 DB08529] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process GGPS1;CES1 9864:[DB01183 DB09266] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;MRC1;ESR1;OPRM1;OPRD1 GO:0006898| receptor-mediated endocytosis ALB;MRC1 GO:0016032| viral reproduction MRC1;CREB1 GO:0071222| cellular response to lipopolysaccharide MRC1;OPRK1;TLR4 9865:[DB01183 DB02011] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways GO:0032868| response to insulin stimulus OPRK1;OTC GO:0001889| liver development UGT1A1;OTC GO:0042493| response to drug OTC;UGT1A1;CREB1;ABCB1 9866:[DB01183 DB04709] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;AR;TLR4;CREB1;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006351| transcription, DNA-dependent CREB1;AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;AR 9867:[DB01183 DB01612] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;NPR1;OPRK1 GO:0006468| protein phosphorylation CREB1;NPR1 GO:0008152| metabolic process CES1;ALDH2;UGT1A1 GO:0055114| oxidation-reduction process ALDH2;CYP3A4;CYP2C8 9868:[DB01183 DB01777] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;AANAT GO:0032868| response to insulin stimulus AANAT;OPRK1 GO:0048511| rhythmic process AANAT;CREB1 GO:0007623| circadian rhythm CREB1;AANAT 9869:[DB01183 DB14518] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0010628| positive regulation of gene expression APP;TLR4 GO:1904646| TLR4;APP GO:1903223| APP;TLR4 GO:0008285| negative regulation of cell proliferation APP;OPRM1 GO:0006811| ion transport ATP1A1;TF;SLCO1A2 GO:0007409| axonogenesis CREB1;APP GO:0034375| high-density lipoprotein particle remodeling ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;APP;TLR4 GO:0044267| cellular protein metabolic process TF;ALB;APP GO:0001895| retina homeostasis TF;ALB GO:0008344| adult locomotory behavior OPRD1;APP GO:0000187| activation of MAPK activity TLR4;APP GO:0006898| receptor-mediated endocytosis ALB GO:1900273| APP;CREB1 GO:0098869| ALB GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;APP;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;APP;OPRM1;OPRD1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;APP GO:0006468| protein phosphorylation CREB1;APP GO:0007613| memory CREB1;APP GO:0043069| negative regulation of programmed cell death ALB GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRK1;OPRD1;OPRM1 GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TLR4 GO:0034121| regulation of toll-like receptor signaling pathway ESR1;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;ESR1 GO:0008542| visual learning APP;CREB1 GO:0010629| negative regulation of gene expression CREB1;APP;ESR1;OPRD1 GO:0007268| synaptic transmission APP;OPRK1;OPRD1;OPRM1 GO:0042493| response to drug ATP1A1;CREB1;UGT1A1;ABCB1 GO:0043687| post-translational protein modification TF;ALB;APP GO:1901215| APP;CREB1 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;CREB1;TLR4;ESR1 GO:0007626| locomotory behavior APP;OPRK1;OPRM1 GO:0043065| positive regulation of apoptotic process APP;CREB1 GO:0002576| platelet degranulation APP;ALB;TF GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0043066| negative regulation of apoptotic process ALB GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;ESR1 GO:0045087| innate immune response TLR4;APP GO:1990090| APP;CREB1 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046330| positive regulation of JNK cascade TLR4;APP 9870:[DB01183 DB07684] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways GO:0001666| response to hypoxia CREB1;PLAT 9871:[DB01183 DB07300] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways GO:0006468| protein phosphorylation CREB1;PDPK1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;PDPK1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;CREB1;ESR1 9872:[DB01183 DB12733] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12733|Dipraglurant GRM5 common genes common pathways GO:0007626| locomotory behavior GRM5;OPRM1;OPRK1 GO:0007268| synaptic transmission OPRD1;GRM5;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GRM5;OPRD1;OPRM1 GO:0007165| signal transduction ESR1;GRM5;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:1904646| GRM5;TLR4 9873:[DB01183 DB02735] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways GO:0008202| steroid metabolic process STS;CYP3A4;CYP2C8;UGT1A1 GO:0043687| post-translational protein modification ALB;STS GO:0008152| metabolic process STS;CES1;UGT1A1 GO:0006706| steroid catabolic process STS;CYP3A4 GO:0006629| lipid metabolic process STS;CYP3A4 9874:[DB01183 DB00867] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PGD;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:1904646| ADRB2;TLR4 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRB2;OPRK1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;ADRB2 9875:[DB01183 DB02507] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 9876:[DB01183 DB06150] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06150|Sulfadimethoxine CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 9877:[DB01183 DB03169] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03169|(S)-Hmg-Coa HMGCR common genes common pathways GO:0007568| aging CREB1;HMGCR GO:0008202| steroid metabolic process HMGCR;CYP3A4;CYP2C8;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;TLR4 GO:0007584| response to nutrient HMGCR;UGT1A1 GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0045471| response to ethanol OPRK1;UGT1A1;HMGCR;OPRM1 GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR;TLR4 GO:0006629| lipid metabolic process HMGCR;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;HMGCR GO:0055114| oxidation-reduction process CYP2C8;HMGCR;CYP3A4 GO:0008542| visual learning CREB1;HMGCR 9878:[DB01183 DB01586] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes SLCO1A2 common pathways GO:0015721| bile acid and bile salt transport SLC10A2;SLC10A1;ALB;SLCO1A2;NR1H4;ABCB11 GO:0043627| response to estrogen stimulus ESR1;OPRK1;ABCC2 GO:0010033| response to organic substance UGT1A1;CREB1;ABCC4 GO:0034142| toll-like receptor 4 signaling pathway NR1H4;TLR4 GO:0006811| ion transport SLC10A1;SLC10A2;SLCO1A2 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0055085| transmembrane transport ABCC2;SLC10A1;SLC10A2;ABCB1;ABCB11;SLCO1A2;ABCC4 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0030855| epithelial cell differentiation AKR1C2;CES1 GO:0032720| negative regulation of tumor necrosis factor production NR1H4;TLR4 GO:0032689| negative regulation of interferon-gamma production TLR4;NR1H4 GO:0002376| immune system process TLR4;NR1H4 GO:0032715| negative regulation of interleukin-6 production NR1H4;TLR4 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0015711| organic anion transport SLCO1A2 GO:0017144| drug metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2C8 GO:0007165| signal transduction ESR1;OPRD1;NR1H4;OPRM1;TLR4;CREB1;OPRK1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;AKR1C2;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;AKR1C2;CYP2C8;UGT1A1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0006810| transport ABCB1;SLC10A2;SLC10A1;ABCC2;ABCB11 GO:0006954| inflammatory response TLR4;NR1H4 GO:0016032| viral reproduction SLC10A1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1H4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1H4;CREB1 GO:0042493| response to drug CYP2E1;ABCC4;CREB1;UGT1A1;ABCC2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;ABCC4;AKR1C2;CYP2C8 GO:0042742| defense response to bacterium NR1H4;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;ABCC2;OPRK1;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;NR1H4 GO:0002576| platelet degranulation ALB;ABCC4 GO:0043066| negative regulation of apoptotic process NR1H4;ALB GO:0071398| cellular response to fatty acid NR1H4;CREB1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2E1;CES1 GO:0045087| innate immune response TLR4;NR1H4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR1H4 GO:0007586| digestion UGT1A1;AKR1C2 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0006629| lipid metabolic process AKR1C2;CYP3A4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ABCC2;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR1H4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;NR1H4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0006351| transcription, DNA-dependent NR1H4;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway NR1H4;ESR1 9879:[DB01183 DB05495] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05495|PG-530742 MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MMP9 GO:0043065| positive regulation of apoptotic process CREB1;MMP9 9880:[DB01183 DB11113] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways GO:0006955| immune response PTGER4;TLR4;OPRK1;OPRD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;PTGER3;OPRD1 GO:0032496| response to lipopolysaccharide TLR4;PTGER4;UGT1A1;OPRM1 GO:0071260| cellular response to mechanical stimulus PTGER4;TLR4 GO:0050729| positive regulation of inflammatory response PTGER4;TLR4 GO:0007186| G-protein coupled receptor signaling pathway PTGER4;OPRK1;PTGER3;OPRD1;OPRM1 GO:0007165| signal transduction OPRM1;PTGER3;OPRD1;ESR1;OPRK1;PTGER4;CREB1;TLR4 9881:[DB01183 DB12339] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12339|Radezolid RRBP1;NIP7 common genes common pathways 9882:[DB01183 DB11085] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11085|Resorcinol TPO common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;TPO;CYP3A4 GO:0098869| TPO;ALB 9883:[DB01183 DB07932] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07932|dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate ESR1;NCOA2 common genes ESR1 common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0006355| regulation of transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;NCOA2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0032355| response to estradiol stimulus ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 9884:[DB01183 DB13772] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 9885:[DB01183 DB03866] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0050727| regulation of inflammatory response PTGS2;ESR1;TLR4 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;OPRK1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;PTGS2 GO:0006954| inflammatory response PTGS2;TLR4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8 GO:0042493| response to drug PTGS2;UGT1A1;CREB1;ABCB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;PTGS2;ESR1 GO:0098869| ALB;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory CREB1;PTGS2 GO:0007568| aging PTGS2;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 GO:0010033| response to organic substance PTGS2;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 9886:[DB01183 DB01926] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01926|Carboxymycobactin S LCN2 common genes common pathways GO:0045087| innate immune response TLR4;LCN2 GO:0002376| immune system process LCN2;TLR4 GO:0006811| ion transport LCN2;SLCO1A2 9887:[DB01183 DB06077] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:1900273| CREB1;DRD2 GO:0007165| signal transduction OPRD1;OPRM1;HTR2A;ESR1;TLR4;CREB1;DRD2;OPRK1 GO:0007610| behavior HTR2A;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;HTR2A;DRD2;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1 GO:0007613| memory HTR2A;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007568| aging HTR2A;CREB1 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0001666| response to hypoxia CREB1;DRD2 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0007409| axonogenesis DRD2;CREB1 GO:0009636| response to toxin CES1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;TLR4;DRD2 GO:0042220| response to cocaine OPRM1;OPRK1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD2 GO:0007626| locomotory behavior OPRM1;OPRK1;DRD2 GO:0048148| behavioral response to cocaine HTR2A;OPRK1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0045471| response to ethanol DRD2;OPRK1;UGT1A1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1;OPRK1 GO:0019233| sensory perception of pain HTR2A;OPRM1;OPRD1;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0016032| viral reproduction CREB1;HTR2A GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning DRD2;CREB1 GO:0043278| response to morphine DRD2;OPRK1;OPRM1 GO:0042493| response to drug HTR2A;DRD2;ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission OPRK1;HTR2A;OPRD1;OPRM1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 9888:[DB01183 DB03085] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03085|Glycolic acid G6PD;thiO common genes common pathways GO:0006695| cholesterol biosynthetic process G6PD;CES1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;G6PD GO:0006629| lipid metabolic process G6PD;CYP3A4 GO:0032094| response to food OPRM1;G6PD GO:0055114| oxidation-reduction process CYP3A4;G6PD;CYP2C8 GO:0014070| response to organic cyclic compound G6PD;UGT1A1 9889:[DB01183 DB12579] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12579|JNJ-37822681 DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0042220| response to cocaine OPRM1;DRD2;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0009636| response to toxin CES1;DRD2 GO:0007409| axonogenesis DRD2;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;DRD2;OPRK1 GO:1900273| DRD2;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway DRD2;OPRK1;OPRD1;OPRM1 GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning CREB1;DRD2 GO:0043278| response to morphine OPRM1;DRD2;OPRK1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug ABCB1;DRD2;UGT1A1;CREB1 GO:0048148| behavioral response to cocaine OPRK1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;DRD2;ESR1 GO:0007626| locomotory behavior OPRM1;OPRK1;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol DRD2;OPRK1;UGT1A1;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 9890:[DB01183 DB03773] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways GO:0008152| metabolic process CES1;AMY2A;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0032094| response to food SLC16A1;OPRM1 GO:0055085| transmembrane transport SLCO1A2;SLC16A7;SLC16A1;ABCB1 9891:[DB01183 DB07460] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways GO:0006468| protein phosphorylation PTK2;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;PTK2 GO:0007411| axon guidance PTK2;CREB1 GO:0045087| innate immune response PTK2;TLR4 GO:0043066| negative regulation of apoptotic process PTK2;ALB GO:0071560| cellular response to transforming growth factor beta stimulus PTK2;CREB1 9892:[DB01183 DB04564] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04564|Gluconolactone LCT common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;LCT 9893:[DB01183 DB05116] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05116|Thymectacin TYMS common genes common pathways GO:0007623| circadian rhythm CREB1;TYMS GO:0045471| response to ethanol UGT1A1;TYMS;OPRK1;OPRM1 GO:0042493| response to drug ABCB1;CREB1;TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0007568| aging CREB1;TYMS GO:0009636| response to toxin CES1;TYMS GO:0014070| response to organic cyclic compound TYMS;UGT1A1 9894:[DB01183 DB00411] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM2;CHRM1;CHRM4;OPRK1;CHRM3 GO:0007165| signal transduction OPRK1;CHRM4;CREB1;TLR4;CHRM3;CHRNA2;CHRM1;ESR1;CHRM2;OPRM1;OPRD1 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CHRM2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA2 GO:0008152| metabolic process UGT1A1;PLA2G4A;CES1 GO:0006629| lipid metabolic process CYP3A4;PLA2G4A GO:0007586| digestion UGT1A1;CHRM3 GO:0035094| response to nicotine CHRNA2;CREB1 9895:[DB01183 DB04860] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04860|Isatoribine TLR7 common genes common pathways GO:0045087| innate immune response TLR7;TLR4 GO:0071260| cellular response to mechanical stimulus TLR7;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR7;TLR4 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR7;TLR4 GO:0051607| defense response to virus TLR7;OPRK1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR7;TLR4 GO:0006954| inflammatory response TLR7;TLR4 GO:0007252| I-kappaB phosphorylation TLR7;TLR4 GO:0006955| immune response OPRK1;TLR4;TLR7;OPRD1 GO:0002224| toll-like receptor signaling pathway TLR7;TLR4 GO:0050729| positive regulation of inflammatory response TLR7;TLR4 GO:0007165| signal transduction CREB1;TLR4;TLR7;OPRK1;ESR1;OPRM1;OPRD1 GO:0032722| positive regulation of chemokine production TLR7;TLR4 GO:0032757| positive regulation of interleukin-8 production TLR7;TLR4 GO:0002376| immune system process TLR4;TLR7 GO:0045359| positive regulation of interferon-beta biosynthetic process TLR4;TLR7 GO:0032755| positive regulation of interleukin-6 production TLR7;TLR4 9896:[DB01183 DB00291] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00291|Chlorambucil GSTP1;SLCO1A2 common genes SLCO1A2 common pathways GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0098869| GSTP1;ALB GO:0015711| organic anion transport SLCO1A2 GO:0006811| ion transport SLCO1A2 GO:0009636| response to toxin GSTP1;CES1 GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;GSTP1 GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;OPRK1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0008152| metabolic process UGT1A1;GSTP1;CES1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;CYP3A4;CES1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 9897:[DB01183 DB08228] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CES1;NQO2;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NQO2 9898:[DB01183 DB05046] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05046|V1003 OPRK1;OPRM1 common genes OPRK1;OPRM1 common pathways GO:0042060| wound healing OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0048148| behavioral response to cocaine OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1 GO:0007218| neuropeptide signaling pathway OPRK1;OPRM1;OPRD1 GO:0009314| response to radiation OPRM1;OPRK1 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:1900745| OPRK1 GO:1903715| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:0032094| response to food OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1 GO:0051607| defense response to virus OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:0006955| immune response OPRD1;TLR4;OPRK1 GO:0042711| maternal behavior OPRK1 GO:0043278| response to morphine OPRM1;OPRK1 GO:0007600| sensory perception OPRK1;OPRM1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:1903937| OPRK1 GO:0032100| positive regulation of appetite OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:1901381| OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0044849| OPRM1;OPRK1 GO:1990708| OPRK1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007610| behavior OPRK1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0042755| eating behavior OPRK1;OPRM1;OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0042220| response to cocaine OPRK1;OPRM1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 9899:[DB01183 DB06871] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06871|17-METHYL-17-ALPHA-DIHYDROEQUILENIN ESR1;NCOA2 common genes ESR1 common pathways GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0032355| response to estradiol stimulus ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;NCOA2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 9900:[DB01183 DB06901] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 9901:[DB01183 DB07691] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0030154| cell differentiation CREB1;PPARD GO:0045600| positive regulation of fat cell differentiation PPARD;CREB1 GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0014823| response to activity CREB1;PPARD GO:0010033| response to organic substance CREB1;UGT1A1;PPARD GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;PPARD GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0006629| lipid metabolic process CYP3A4;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0042060| wound healing PPARD;OPRM1 GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0006351| transcription, DNA-dependent ESR1;PPARD;CREB1 GO:0043401| steroid hormone mediated signaling pathway PPARD;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 9902:[DB01183 DB01214] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;OPRK1;ADRB1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0007165| signal transduction OPRK1;ADRB1;TLR4;CREB1;ADRB2;ESR1;OPRD1;OPRM1 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:1904646| TLR4;ADRB2 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ADRB2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CES1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 9903:[DB01183 DB00044] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00044|Lutropin alfa LHCGR common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;LHCGR;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;LHCGR;OPRK1 GO:0008584| male gonad development ESR1;LHCGR GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;LHCGR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LHCGR;ESR1;OPRD1;OPRM1;OPRK1 9904:[DB01183 DB08808] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;ADRB2;ADRB1;OPRK1;ADRB3;CREB1;TLR4 GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0007568| aging CREB1;ADRB3 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRM1;OPRD1;OPRK1;ADRB3;ADRB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:1904646| ADRB2;TLR4 GO:0042755| eating behavior ADRB3;OPRK1;OPRM1;OPRD1 9905:[DB01183 DB07693] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport ABCB1;TTR 9906:[DB01183 DB09290] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09290|Ramosetron HTR3A;CYP1A2 common genes common pathways GO:0007268| synaptic transmission OPRK1;HTR3A;OPRM1;OPRD1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0045471| response to ethanol OPRK1;HTR3A;UGT1A1;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0006811| ion transport HTR3A;SLCO1A2 GO:0042220| response to cocaine OPRM1;OPRK1;HTR3A GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0007165| signal transduction HTR3A;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0071363| cellular response to growth factor stimulus CREB1;HTR3A;OPRD1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 9907:[DB01183 DB06064] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06064|KAI-1455 PRKCE common genes common pathways GO:0006468| protein phosphorylation CREB1;PRKCE GO:0071456| cellular response to hypoxia PRKCE;OPRD1 GO:0002376| immune system process TLR4;PRKCE GO:0007165| signal transduction PRKCE;ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1 GO:0043278| response to morphine PRKCE;OPRM1;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;PRKCE GO:0031663| lipopolysaccharide-mediated signaling pathway PRKCE;TLR4 GO:0071361| cellular response to ethanol PRKCE;UGT1A1 9908:[DB01183 DB07517] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 9909:[DB01183 DB08157] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways GO:0010033| response to organic substance CA2;UGT1A1;CREB1 GO:0043627| response to estrogen stimulus ESR1;CA2;OPRK1 GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0045672| positive regulation of osteoclast differentiation CREB1;CA2 9910:[DB01183 DB01309] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01309|Insulin Glulisine INSR common genes common pathways GO:0000187| activation of MAPK activity INSR;TLR4 GO:0008584| male gonad development ESR1;INSR GO:0007186| G-protein coupled receptor signaling pathway INSR;OPRK1;OPRD1;OPRM1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;INSR GO:0007613| memory INSR;CREB1 GO:0006468| protein phosphorylation CREB1;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;TLR4;OPRM1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;INSR;CREB1 9911:[DB01183 DB00040] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways GO:0042594| response to starvation UGT1A1;GCGR GO:0007165| signal transduction CREB1;TLR4;GLP1R;GLP2R;OPRK1;ESR1;GCGR;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;GLP1R GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;GCGR;GLP2R;GLP1R;OPRK1 GO:0007584| response to nutrient GCGR;UGT1A1 9912:[DB01183 DB11087] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008202| steroid metabolic process NR1I2;UGT1A1;CYP2C8;CYP3A4 GO:0007165| signal transduction OPRK1;TLR4;NR1I2;CREB1;OPRD1;OPRM1;ESR1 GO:0010628| positive regulation of gene expression NR1I2;TLR4 GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NR1I2;ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;NR1I2;CES1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR1I2;TLR4;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR1I2;ESR1 GO:0042738| exogenous drug catabolic process NR1I2;CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I2;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 9913:[DB01183 DB11988] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11988|Ocrelizumab MS4A1 common genes common pathways 9914:[DB01183 DB01700] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01700|AICA ribonucleotide ATIC common genes common pathways GO:0008152| metabolic process CES1;ATIC;UGT1A1 GO:0031100| organ regeneration UGT1A1;ATIC 9915:[DB01183 DB05455] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05455|SR 121463 AVPR1B common genes common pathways GO:0007165| signal transduction OPRK1;AVPR1B;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0032870| cellular response to hormone stimulus UGT1A1;AVPR1B GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;AVPR1B GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;AVPR1B;OPRK1 9916:[DB01183 DB14034] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14034|Darglitazone PPARG common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045087| innate immune response TLR4;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0042493| response to drug ABCB1;PPARG;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;PPARG;CREB1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRD1;OPRM1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0048511| rhythmic process PPARG;CREB1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG 9917:[DB01183 DB03100] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03100|6-Nitroindazole NOS2;NOS3 common genes common pathways GO:0009617| response to bacterium TLR4;NOS2 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOS3;NOS2;CYP3A4 GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide NOS2;TLR4;UGT1A1;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;NOS2;OPRK1 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 GO:0001666| response to hypoxia NOS2;CREB1 9918:[DB01183 DB07559] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;DHODH GO:0007595| lactation CREB1;DHODH GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;DHODH GO:0042594| response to starvation UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process DHODH;CREB1 9919:[DB01183 DB00640] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways GO:0001889| liver development ADA;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;ADORA2A;ADORA1 GO:0097190| apoptotic signaling pathway ADORA1;TLR4 GO:0043066| negative regulation of apoptotic process ADORA1;ALB;ADA GO:0007626| locomotory behavior OPRM1;OPRK1;ADORA2A GO:0006355| regulation of transcription, DNA-dependent CREB1;ADORA2A;ESR1 GO:0042493| response to drug ADA;UGT1A1;ADORA2A;CREB1;ABCB1 GO:0006954| inflammatory response ADORA1;TLR4;ADORA2A;ADORA3 GO:0043278| response to morphine OPRK1;ADA;OPRM1 GO:0007600| sensory perception OPRM1;ADORA2A;OPRK1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0007186| G-protein coupled receptor signaling pathway ADORA2A;ADORA3;ADORA1;ADORA2B;OPRK1;OPRD1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADORA1;OPRK1 GO:0007568| aging CREB1;ADA GO:0032755| positive regulation of interleukin-6 production TLR4;ADORA2B GO:0032722| positive regulation of chemokine production ADORA2B;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;ADORA2A;ADORA3;ADORA1;CREB1;ADORA2B;OPRK1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADORA1;OPRK1 GO:0042755| eating behavior ADORA2A;OPRK1;OPRM1;OPRD1 GO:0044267| cellular protein metabolic process ADORA2A;ADORA2B;ALB GO:0000187| activation of MAPK activity TLR4;ADORA2B GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1 GO:0030890| positive regulation of B cell proliferation ADA;TLR4 GO:0001666| response to hypoxia ADA;CREB1;ADORA1 GO:0008285| negative regulation of cell proliferation ADORA1;ADORA2A;ADORA3;OPRM1 9920:[DB01183 DB04429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04429|4'-Hydroxyflavanone SHBG common genes common pathways 9921:[DB01183 DB08692] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways GO:0007586| digestion UGT1A1;CTRB1 9922:[DB01183 DB03962] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PGD 9923:[DB01183 DB06153] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0009636| response to toxin CES1;HTR1D GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADRA2C;OPRK1 GO:0042220| response to cocaine OPRM1;HTR1B;OPRK1 GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2B;HTR2C;ADRA1A;TLR4;HTR2A;OPRM1 GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;CREB1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;HTR1D;OPRD1;OPRM1;HTR1B GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;HTR1B;OPRK1;HTR2B;HTR2C;ADRA2A;CHRM3;ADRA1D;ADRA1B;OPRD1;HTR1D;HRH1;OPRM1;ADRA2B;HTR2A;CHRM2;HTR1A;CHRM1;ADRA2C GO:0007568| aging HTR2A;ADRA1A;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;HTR1D;ADRA2A;OPRK1;HTR1B GO:0007613| memory CREB1;HRH1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;HTR2A;ESR1;OPRM1;ADRA1A;ADRA1D GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0007610| behavior HTR2C;HTR2B;OPRK1;HTR1B;HTR1A;HTR2A GO:0007165| signal transduction ADRA1A;HTR1B;ADRA2A;HTR2C;HTR2B;OPRK1;ADRA1D;CHRM3;CREB1;TLR4;ADRA1B;OPRM1;HRH1;HTR1D;OPRD1;ESR1;CHRM1;ADRA2C;HTR1A;CHRM2;ADRA2B;HTR2A GO:0042493| response to drug HTR2B;HTR2C;ADRA1A;HTR1B;ABCB1;CREB1;UGT1A1;HTR2A GO:0007268| synaptic transmission HTR2A;HTR1D;OPRD1;OPRM1;OPRK1;HTR2C;HTR1B GO:0016032| viral reproduction HTR2A;CREB1 GO:0006954| inflammatory response TLR4;HRH1 GO:0008542| visual learning CREB1;HRH1 GO:0051000| positive regulation of nitric-oxide synthase activity HTR2B;ESR1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;ESR1;HTR2A;OPRM1;HRH1;OPRD1;HTR2C;HTR2B;OPRK1;ADRA1A;ADRA1D GO:0045471| response to ethanol OPRK1;HTR1B;UGT1A1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HTR2B GO:0008152| metabolic process UGT2B10;UGT1A1;CES1 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0007626| locomotory behavior HTR2C;OPRK1;OPRM1 GO:0006629| lipid metabolic process CYP3A4;UGT2B10 GO:0007586| digestion UGT1A1;CHRM3 9924:[DB01183 DB06533] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;CREB1;PPARG;TLR4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0048511| rhythmic process PPARA;CREB1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0001666| response to hypoxia PPARA;CREB1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0030855| epithelial cell differentiation CES1;PPARG GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA GO:0045087| innate immune response PPARG;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;ESR1;PPARG GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;ESR1;TLR4;PPARG;CREB1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1;PPARA GO:0006351| transcription, DNA-dependent PPARG;CREB1;PPARA;ESR1 GO:0042060| wound healing OPRM1;PPARA GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1;PPARA GO:0042752| regulation of circadian rhythm PPARA;PPARG;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:1901215| CREB1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;PPARA;ESR1 GO:0042493| response to drug ABCB1;PPARG;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent PPARA;ESR1;PPARG;CREB1 9925:[DB01183 DB06472] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0002576| platelet degranulation ITGA2B;ALB;ITGB3 GO:0042060| wound healing ITGB3;OPRM1 GO:0016032| viral reproduction CREB1;ITGB3 9926:[DB01183 DB07247] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways GO:0007623| circadian rhythm CREB1;F7 GO:0014070| response to organic cyclic compound F7;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;F7 GO:0001666| response to hypoxia CREB1;F7 GO:0032355| response to estradiol stimulus ESR1;F7 GO:0031100| organ regeneration UGT1A1;F7 9927:[DB01183 DB07140] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHFR 9928:[DB01183 DB05916] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05916|CT-011 PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PDCD1;ALB GO:0043065| positive regulation of apoptotic process CREB1;PDCD1 GO:0002376| immune system process PDCD1;TLR4 GO:0007165| signal transduction ESR1;OPRD1;PDCD1;OPRM1;OPRK1;TLR4;CREB1 9929:[DB01183 DB07814] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07814|Gibberellic acid AADACL2 common genes common pathways GO:0008152| metabolic process UGT1A1;AADACL2;CES1 9930:[DB01183 DB01902] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ERO1B;CYP3A4 9931:[DB01183 DB00060] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00060|Interferon beta-1a IFNAR1;IFNAR2 common genes common pathways GO:0051607| defense response to virus IFNAR2;OPRK1 GO:0032496| response to lipopolysaccharide IFNAR1;OPRM1;TLR4;UGT1A1 9932:[DB01183 DB02568] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02568|Peldesine PNP common genes common pathways GO:0006955| immune response OPRD1;PNP;TLR4;OPRK1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PNP 9933:[DB01183 DB02271] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02271|S-(2-Oxo)Pentadecylcoa NMT2 common genes common pathways 9934:[DB01183 DB06750] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLCO1B3 GO:0006811| ion transport SLCO1B3;SLCO1A2 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1A2;ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1A2 GO:0015711| organic anion transport SLCO1A2;SLCO1B3 9935:[DB01183 DB03609] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03609|3-Deoxyguanosine PNP common genes common pathways GO:0006955| immune response TLR4;PNP;OPRK1;OPRD1 GO:0042493| response to drug UGT1A1;CREB1;PNP;ABCB1 9936:[DB01183 DB13949] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways GO:0032355| response to estradiol stimulus ESR1;CALR GO:0050821| protein stabilization CREB1;CALR GO:0006898| receptor-mediated endocytosis ALB;CALR;TFRC GO:0006811| ion transport SLCO1A2;TF GO:0001895| retina homeostasis TF;ALB GO:0044267| cellular protein metabolic process ALB;TF GO:0010628| positive regulation of gene expression TLR4;CALR GO:0030890| positive regulation of B cell proliferation TLR4;TFRC GO:1990830| TFRC;CREB1 GO:0010033| response to organic substance UGT1A1;CALR;CREB1 GO:0042060| wound healing OPRM1;ITGB3 GO:0002576| platelet degranulation TF;ITGB3;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1 GO:0042981| regulation of apoptotic process CREB1;CALR;ESR1 GO:0042493| response to drug ABCB1;CALR;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;CALR GO:0043687| post-translational protein modification ALB;TF GO:0016032| viral reproduction TFRC;ITGB3;CREB1 9937:[DB01183 DB08811] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0007165| signal transduction OPRK1;PDE3A;PDE2A;CREB1;TLR4;PDE10A;OPRM1;OPRD1;PDE4A;ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0070588| calcium ion transmembrane transport PDE2A;OPRM1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0050729| positive regulation of inflammatory response PDE2A;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE3A;PDE2A;PDE10A;OPRM1;OPRD1;PDE4A GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0071260| cellular response to mechanical stimulus TLR4;PDE2A GO:0006629| lipid metabolic process CYP3A4;PDE3A GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PDE3A;PDE2A GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0008152| metabolic process PDE10A;CES1;UGT1A1;PDE2A GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;PDE3A 9938:[DB01183 DB01092] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes SLCO1A2 common pathways GO:0015711| organic anion transport SLCO1C1;SLCO1B3;SLCO1B1;SLCO1A2 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP2C8;CYP3A4 GO:0007568| aging CYP1A1;CREB1 GO:0007613| memory CREB1;ATP1A3 GO:0030154| cell differentiation CREB1;SLCO4C1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2;ALB;SLCO4C1;SLCO1C1 GO:0010033| response to organic substance UGT1A1;CYP1A1;CREB1 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:1904646| ATP1A3;TLR4 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;SLCO1A2;ALB;SLCO1C1 GO:0008344| adult locomotory behavior ATP1A3;ATP1A2;OPRD1 GO:0055085| transmembrane transport SLCO4C1;ABCB1;SLCO1C1;SLCO1B3;SLC22A8;SLCO1B1;SLCO1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0009636| response to toxin CYP1A1;SLC22A8;CES1 GO:0002933| CYP3A4;CYP2C8;CYP1A1 GO:0006811| ion transport SLCO4C1;ATP1A3;SLCO1C1;ATP1A2;SLC22A8;SLCO1B1;ATP1A1;SLCO1B3;SLCO1A2 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4;ATP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;ATP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A1;OPRM1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1 GO:0035094| response to nicotine ATP1A2;CREB1 GO:0008542| visual learning ATP1A3;CREB1;ATP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1;CYP2C8 GO:0032094| response to food CYP1A1;OPRM1 GO:0042493| response to drug ATP1A1;UGT1A1;CYP1A1;CREB1;ATP1A3;ABCB1 9939:[DB01183 DB01077] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways GO:0006810| transport ABCB1;ATP6V1A GO:0006811| ion transport SLCO1A2;ATP6V1A 9940:[DB01183 DB03255] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03255|Phenol cobT;ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB 9941:[DB01183 DB07437] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07437|1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE UPP1 common genes common pathways 9942:[DB01183 DB05125] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05125|SC12267 DHODH common genes common pathways GO:0007595| lactation DHODH;CREB1 GO:0042493| response to drug DHODH;ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation UGT1A1;DHODH GO:0014070| response to organic cyclic compound DHODH;UGT1A1 9943:[DB01183 DB05487] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes ESR1 common pathways GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0006954| inflammatory response NFKB2;TLR4;NFKB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;NFKB2;TLR4 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;NFKB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent NFKB2;CREB1;NFKB1;ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1;NFKB1 GO:0071260| cellular response to mechanical stimulus TLR4;NFKB1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NFKB1;NFKB2 GO:0045087| innate immune response TLR4;NFKB2;NFKB1 GO:0043066| negative regulation of apoptotic process NFKB1;ALB GO:0060065| uterus development ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NFKB1;CREB1;NFKB2;TLR4 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0071222| cellular response to lipopolysaccharide NFKB1;OPRK1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0006351| transcription, DNA-dependent NFKB2;CREB1;NFKB1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;NFKB2;OPRM1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0048511| rhythmic process NFKB2;CREB1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0006366| transcription from RNA polymerase II promoter NFKB2;CREB1;ESR1;NFKB1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction CREB1;TLR4;NFKB2;OPRK1;OPRM1;OPRD1;ESR1;NFKB1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB1;NFKB2;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0007568| aging CREB1;NFKB2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0032355| response to estradiol stimulus ESR1 9944:[DB01183 DB00942] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00942|Cycrimine CHRM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM1;OPRD1;OPRM1;OPRK1 GO:0007165| signal transduction ESR1;CHRM1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 9945:[DB01183 DB02761] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways GO:0030855| epithelial cell differentiation TST;CES1 9946:[DB01183 DB08201] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08201|(1S)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE;UGT1A1;CREB1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 9947:[DB01183 DB08077] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways GO:0098869| HBB;HBA1;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;HBB;ESR1;OPRM1 GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 9948:[DB01183 DB14533] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes ESR1 common pathways GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation FN1;AGT;ESR1 GO:1904646| PARP1;APP;TLR4 GO:0010628| positive regulation of gene expression MDM2;APP;TP53;CLU;TLR4;FN1;GSN;MT3;INS GO:0001666| response to hypoxia MT3;CREB1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0032460| negative regulation of protein oligomerization OPRD1;INS GO:1903428| TLR4;HDAC4 GO:0008584| male gonad development ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC4 GO:0016579| protein deubiquitination TP53;MDM2;BRCC3;ESR1 GO:0010033| response to organic substance UGT1A1;CREB1;SOD1 GO:0008285| negative regulation of cell proliferation OPRM1;NME1;HDAC1;HDAC4;APP;TP53;TP73 GO:1903223| APP;TLR4 GO:0048511| rhythmic process HDAC1;CREB1;TP53 GO:0007584| response to nutrient APOA1;UGT1A1 GO:0043627| response to estrogen stimulus APOA2;APOA1;OPRK1;ESR1 GO:0009636| response to toxin PON1;CES1;MGMT;MDM2 GO:0014070| response to organic cyclic compound MGMT;TP53;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;INS GO:0034375| high-density lipoprotein particle remodeling APOE;APOA4;APOA2;ALB;APOA1 GO:0006811| ion transport TF;SLCO1A2;CP;GLRA1 GO:0007409| axonogenesis APP;CREB1 GO:0030879| mammary gland development NME1;CREB1 GO:0044267| cellular protein metabolic process FGA;KNG1;F2;IGFALS;AHSG;ALB;APOA1;APOE;APOA4;APOA2;APP;SEMG1;FN1;CP;SERPIND1;INS;TTR;SERPINA1;ITIH2;APOL1;P4HB;GSN;APCS;TF;APLP2;C3 GO:0007179| transforming growth factor beta receptor signaling pathway APOA1;CREB1;PARP1 GO:0000187| activation of MAPK activity APP;TLR4;TP73;C5;SOD1 GO:0030855| epithelial cell differentiation KRT14;CES1 GO:0042220| response to cocaine OPRM1;MDM2;OPRK1 GO:0001895| retina homeostasis ALB;JCHAIN;PRDX1;KRT1;IGHA1;SOD1;TF GO:0008344| adult locomotory behavior OPRD1;APP GO:0055085| transmembrane transport APOA1;ABCB1;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MT3;TLR4;S100A7;APP;FGA GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0006366| transcription from RNA polymerase II promoter TP73;CREB1;TP53;ESR1;PARP1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0098869| S100A9;ALB;HBB;HBA1;APOE GO:0045429| positive regulation of nitric oxide biosynthetic process INS;AGT;ESR1;OPRM1;TLR4;HBB;CLU;APP GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1900273| INS;APP;CREB1 GO:1903799| ESR1 GO:0031100| organ regeneration APOA1;APOA2;UGT1A1 GO:0002376| immune system process TLR4;IGHM;C1QB;C8B;C1R;CLU;CFB;IGKV1-17;FGA;FCN3;CFH;C1QC;C3;CFI;IGHA1;C1S;C5;C4BPB;C8A;S100A9;IGLV3-21;S100A8;C4BPA;PGLYRP2;C4B;C8G GO:0006898| receptor-mediated endocytosis HPR;HBA1;HBB;APOE;IGKV1-17;APOA1;ALB;APOBR;JCHAIN;IGHA1;CFI;VTN;APOL1;IGLV3-21 GO:0032689| negative regulation of interferon-gamma production TLR4;PGLYRP2 GO:0002064| epithelial cell development ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1 GO:0007165| signal transduction IGFALS;OPRK1;FGA;CREB1;TLR4;BDKRB1;PDIA3;JUP;ESR1;C3;OPRM1;OPRD1 GO:0048545| response to steroid hormone stimulus MDM2;UGT1A1 GO:0008202| steroid metabolic process APOL1;CYP3A4;UGT1A1;APOE;CYP2C8;APOA1;APOBR GO:0050729| positive regulation of inflammatory response TLR4;S100A9;S100A8;AGT GO:0014002| astrocyte development TLR4;MT3;S100A8;S100A9 GO:0007186| G-protein coupled receptor signaling pathway AGT;INS;OPRD1;OPRM1;C3;APLP2;C5;F2;KNG1;APOA1;OPRK1;APP;BDKRB1;APOE GO:0050821| protein stabilization APOA1;CPN2;CREB1;CLU;MT3 GO:0032732| positive regulation of interleukin-1 production HDAC1;TLR4 GO:0071363| cellular response to growth factor stimulus OPRD1;MDM2;CREB1 GO:0051384| response to glucocorticoid stimulus CPN1;UGT1A1;APOA2 GO:0032355| response to estradiol stimulus ESR1;AGT GO:0006810| transport TTR;ABCB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1;APP GO:0007568| aging GSN;SOD1;AGT;TP53;CREB1;KRT16;KRT14 GO:0002224| toll-like receptor signaling pathway FGA;TLR4;S100A9;S100A8 GO:0007204| elevation of cytosolic calcium ion concentration AGT;OPRM1;ESR1;KNG1;APP;BDKRB1 GO:0071456| cellular response to hypoxia TP53;MDM2;MT3;P4HB;OPRD1 GO:0006338| chromatin remodeling HDAC1;HDAC4;ESR1 GO:0030154| cell differentiation TP53;CREB1;KRT6A;NME1 GO:0006468| protein phosphorylation APP;CREB1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0007613| memory APP;CREB1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006955| immune response IL3;IGLV3-21;VTN;C8A;OPRD1;IGHA1;C1QC;C3;IGKV1-17;JCHAIN;OPRK1;C8B;C1R;TLR4 GO:0016032| viral reproduction CFH;TP73;TP53;MDM2;APOA2;HDAC1;IDE;CREB1;SIVA1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;HDAC4;ESR1;JUP GO:0071391| cellular response to estrogen stimulus MDM2;ESR1 GO:0060068| vagina development ESR1 GO:0006954| inflammatory response KNG1;SERPINA3;BDKRB1;TLR4;KRT16;HDAC4;C4B;S100A9;S100A8;C3;KLKB1;C5 GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CLU;APP;INS;AGT;S100A8;S100A9 GO:0048863| stem cell differentiation ESR1;A2M GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;ORM2 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0008542| visual learning CREB1;APP GO:0043278| response to morphine MDM2;OPRK1;OPRM1 GO:0051924| regulation of calcium ion transport AGT;OPRD1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;HDAC1;CLU GO:0007595| lactation CREB1;NME1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0006953| acute-phase response FN1;UGT1A1;ORM2;AHSG;SERPINA3;F2;ITIH4;APCS;INS;SERPINA1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AGT;MT3;TP53;CREB1;HDAC4;HDAC1;TP73 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;APOA2 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0051607| defense response to virus FCN3;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP1;INS;HDAC8;EEF1A1;HDAC1;CREB1;HDAC4;TP53;TP73;ENO1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;APP;GLRA1 GO:0042493| response to drug MGMT;SOD1;NME1;HDAC4;CREB1;HDAC1;UGT1A1;TP53;MDM2;APOA2;APOA1;ABCB1;TP73 GO:0010629| negative regulation of gene expression APP;MDM2;CREB1;HDAC1;AGT;HDAC8;NME1;OPRD1;ESR1 GO:0042742| defense response to bacterium S100A8;S100A9;DCD;TLR4 GO:0043687| post-translational protein modification FN1;APOE;APP;APOA2;ALB;APOA1;AHSG;KNG1;FGA;C3;APLP2;P4HB;ITIH2;APOL1;TF;SERPINA1;CP;SERPIND1 GO:0043491| protein kinase B signaling cascade MT3;CREB1;MDM2 GO:0055114| oxidation-reduction process CP;CCS;ADH1C;P4HB;SOD1;CYP3A4;PRDX1;CYP2C8;PDIA3;GAPDHS GO:1901215| MT3;APOE;APP;CREB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0043066| negative regulation of apoptotic process MT3;SOD1;MGMT;ALB;TP53;MDM2;HDAC1;MMP9 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0060065| uterus development ESR1 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;APP GO:0008152| metabolic process TPI1;CPE;CES1;ASPA;UGT1A1;IDE GO:0071398| cellular response to fatty acid CREB1;NME1 GO:0007626| locomotory behavior OPRM1;SOD1;OPRK1;APP GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0007218| neuropeptide signaling pathway OPRD1;CPE;OPRM1;OPRK1;GLRA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PARP1;TP73;TLR4;HDAC1;CREB1;HDAC4;APP;TP53 GO:0050829| defense response to Gram-negative bacterium APP;TLR4;IGHM;S100A7;DCD GO:0043065| positive regulation of apoptotic process SOD1;KNG1;TP73;MMP9;CREB1;APP;TP53;CLU GO:0002576| platelet degranulation SERPINA1;A2M;TF;ITIH4;SOD1;APLP2;A1BG;SERPINA3;FGA;KNG1;ITIH3;ALB;APOA1;AHSG;CLU;ORM2;ALDOA;SERPINA4;APP;FN1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0050727| regulation of inflammatory response TLR4;AHSG;S100A8;S100A9;ESR1;PGLYRP2 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0071260| cellular response to mechanical stimulus AGT;TLR4;HDAC4 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0006629| lipid metabolic process APOL1;C3;PON1;CYP3A4;APOA1;APOBR;CLU;APOE GO:0042981| regulation of apoptotic process ESR1;NME1;AGT;CREB1;TP53;TP73 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:1990090| CREB1;APP GO:0045087| innate immune response C8G;C4B;PGLYRP2;C4BPA;S100A8;APOL1;F12;S100A9;C8A;C4BPB;APCS;C5;C1S;IGHA1;CFI;C3;C1QC;CFH;FCN3;FGA;CFB;JCHAIN;CLU;C1R;APP;C8B;C1QB;KRT16;S100A7;IGHM;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP73;ENO1;HDAC4;HDAC1;TP53;APP;MDM2;HDAC8;ESR1;PARP1 GO:0071294| cellular response to zinc ion CREB1;GLRA1;MT1A;MT2A;PARP1 GO:0046889| positive regulation of lipid biosynthetic process INS;CREB1;APOE GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0032496| response to lipopolysaccharide S100A8;OPRM1;HDAC1;S100A7;TLR4;UGT1A1;BDKRB1 GO:0042060| wound healing FN1;TP53;DSP;GSN;OPRM1;S100A8;KRT6A;INS GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;APOE GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006351| transcription, DNA-dependent HDAC8;ESR1;PARP1;TP73;ENO1;HDAC1;EEF1A1;HDAC4;CREB1;TP53 GO:0019233| sensory perception of pain OPRD1;OPRM1;BDKRB1;OPRK1 GO:0006695| cholesterol biosynthetic process CES1;APOA4;APOA1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;INS;APOE GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0046330| positive regulation of JNK cascade APP;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;OPRM1 GO:0000060| protein import into nucleus, translocation MT3;OPRD1 GO:0045471| response to ethanol S100A8;OPRM1;GSN;MGMT;SOD1;UGT1A1;TP53;TUFM;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;AGT;OPRD1;OPRM1;ESR1 GO:0097190| apoptotic signaling pathway PDCD6;TLR4 9949:[DB01183 DB06837] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways GO:0042742| defense response to bacterium TLR4;ADAMTS5 9950:[DB01183 DB07962] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR GO:0006810| transport ABCB1;TTR 9951:[DB01183 DB03861] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1;KCNMB2 GO:0007626| locomotory behavior OPRK1;HEXB;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;HEXB;TLR4;CREB1 GO:0008152| metabolic process CES1;HEXB;UGT1A1 GO:0006811| ion transport SLCO1A2;KCNMB2 GO:0044267| cellular protein metabolic process HEXB;ALB 9952:[DB01183 DB07714] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;GSR;CYP3A4 GO:0098869| GSR;ALB 9953:[DB01183 DB01966] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PSAP GO:0002576| platelet degranulation ALB;PSAP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;PSAP;OPRK1 9954:[DB01183 DB04816] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04816|Dantron ALB common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 9955:[DB01183 DB05076] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05076|Fenretinide RBP4 common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1;RBP4;OPRM1 GO:0060065| uterus development RBP4;ESR1 GO:0060068| vagina development ESR1;RBP4 9956:[DB01183 DB04846] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007165| signal transduction ADRA2A;OPRK1;ADRB3;ADRB1;CREB1;TLR4;ESR1;ADRA2C;ADRB2;ADRA2B;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;OPRK1;ADRB3;ADRB1;ADRA2C;ADRB2;ADRA2B;OPRM1;OPRD1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1 GO:0007568| aging CREB1;ADRB3 GO:1904646| TLR4;ADRB2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0051930| regulation of sensory perception of pain OPRK1;ADRA2C;OPRD1;OPRM1 GO:0042755| eating behavior OPRK1;ADRB3;OPRD1;OPRM1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 9957:[DB01183 DB08660] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08660|1,2,5,8-tetrahydroxyanthracene-9,10-dione CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0007165| signal transduction ESR1;CSNK2A1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0006468| protein phosphorylation CREB1;CSNK2A1 GO:0048511| rhythmic process CREB1;CSNK2A1 9958:[DB01183 DB05713] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05713|LY-517717 F10 common genes common pathways 9959:[DB01183 DB00992] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00992|Methyl aminolevulinate FCGR1A common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FCGR1A GO:0002376| immune system process FCGR1A;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;FCGR1A;OPRK1 GO:0045087| innate immune response FCGR1A;TLR4 GO:0006955| immune response OPRD1;TLR4;FCGR1A;OPRK1 9960:[DB01183 DB03994] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03994|Ethanolamine ANXA3 common genes common pathways GO:0070848| response to growth factor stimulus OPRM1;ANXA3 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ANXA3 GO:0043086| negative regulation of catalytic activity ANXA3;UGT1A1 GO:0042742| defense response to bacterium TLR4;ANXA3 GO:0031100| organ regeneration ANXA3;UGT1A1 GO:0051384| response to glucocorticoid stimulus ANXA3;UGT1A1 9961:[DB01183 DB04400] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0035094| response to nicotine CREB1;TH GO:0042493| response to drug ABCB1;UGT1A1;CREB1;TH GO:0010629| negative regulation of gene expression CREB1;NOS2;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PCBD1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PCBD1;CREB1 GO:0009617| response to bacterium TLR4;NOS2 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOS2;PAH;PCBD1;CYP3A4;TH GO:0070848| response to growth factor stimulus OPRM1;TH GO:0007626| locomotory behavior OPRK1;OPRM1;TH GO:0071222| cellular response to lipopolysaccharide TLR4;NOS2;OPRK1 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0008152| metabolic process UGT1A1;PAH;CES1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;TH;UGT1A1;TLR4;NOS2 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;TH GO:0006351| transcription, DNA-dependent PCBD1;ESR1;CREB1 GO:0001666| response to hypoxia NOS2;CREB1;TH GO:0014823| response to activity TH;CREB1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1;TH GO:0014070| response to organic cyclic compound UGT1A1;TH GO:0048545| response to steroid hormone stimulus UGT1A1;TH GO:0032355| response to estradiol stimulus ESR1;TH GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;TH GO:0007613| memory TH;CREB1 9962:[DB01183 DB01791] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways GO:0071222| cellular response to lipopolysaccharide TLR4;PDE4B;OPRK1;PDE4D GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4;PDE4B GO:0007165| signal transduction ESR1;OPRM1;PDE4A;OPRD1;PDE4D;CREB1;TLR4;PDE4C;PDE4B;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway PDE4C;PDE4B;OPRK1;OPRM1;OPRD1;PDE4A;PDE4D GO:0007568| aging CREB1;PDE4D 9963:[DB01183 DB00896] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0007165| signal transduction NR3C1;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0036378| CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NR3C1;ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 9964:[DB01183 DB04594] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways GO:0007584| response to nutrient HMGCL;UGT1A1 GO:0042594| response to starvation UGT1A1;HMGCL GO:0006629| lipid metabolic process CYP3A4;HMGCL GO:0001889| liver development HMGCL;UGT1A1 9965:[DB01183 DB00967] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes ABCB1 common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HRH1;OPRD1;OPRM1;OPRK1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;UGT1A1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2C8;CYP2C19;CYP2D6;CYP2C9 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP1A2;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 GO:0007613| memory CREB1;HRH1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HRH1;OPRD1;OPRK1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2C9;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C9;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;UGT1A1;CYP2C9;CYP1A2;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;HRH1;OPRD1;CREB1;TLR4;OPRK1 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP2C8;CYP3A4;CYP1A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 9966:[DB01183 DB03645] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways GO:0007568| aging CREB1;ENO3 GO:0042493| response to drug ABCB1;ENO3;CREB1;UGT1A1 9967:[DB01183 DB02581] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;IL2;ESR1 GO:0043066| negative regulation of apoptotic process ALB;IL2 GO:0045471| response to ethanol OPRM1;IL2;OPRK1;UGT1A1 GO:0032729| positive regulation of interferon-gamma production IL2;TLR4 GO:0006955| immune response IL2;OPRK1;TLR4;OPRD1 GO:0002376| immune system process IL2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;IL2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;IL2;OPRD1;OPRM1 GO:0050729| positive regulation of inflammatory response IL2;TLR4 GO:0030890| positive regulation of B cell proliferation TLR4;IL2 9968:[DB01183 DB00485] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0007586| digestion UGT1A1;SLC15A1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006811| ion transport SLCO1A2;SLC15A2;SLC15A1 GO:0055085| transmembrane transport SLCO1A2;SLC15A2;ABCB1;SLC15A1 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 9969:[DB01183 DB06599] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06599|Lexatumumab TNFRSF10B common genes common pathways GO:0071260| cellular response to mechanical stimulus TLR4;TNFRSF10B GO:0042981| regulation of apoptotic process ESR1;TNFRSF10B;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNFRSF10B GO:0032496| response to lipopolysaccharide OPRM1;TNFRSF10B;UGT1A1;TLR4 GO:0006955| immune response OPRD1;TNFRSF10B;OPRK1;TLR4 GO:0006954| inflammatory response TNFRSF10B;TLR4 GO:0007165| signal transduction OPRK1;TLR4;CREB1;TNFRSF10B;ESR1;OPRD1;OPRM1 9970:[DB01183 DB05552] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05552|TG100-115 PIK3CD;PIK3CG common genes common pathways GO:0045087| innate immune response PIK3CG;TLR4;PIK3CD GO:0006954| inflammatory response PIK3CG;TLR4;PIK3CD GO:0002376| immune system process PIK3CD;TLR4;PIK3CG GO:0007165| signal transduction OPRK1;PIK3CD;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PIK3CG;OPRD1;OPRM1 GO:0030154| cell differentiation PIK3CD;CREB1 GO:0006468| protein phosphorylation PIK3CD;CREB1;PIK3CG GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;PIK3CG GO:0010628| positive regulation of gene expression TLR4;PIK3CD GO:0007411| axon guidance PIK3CD;CREB1 9971:[DB01183 DB05471] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways GO:0007165| signal transduction CREB1;NFKB2;TLR4;OPRK1;ESR1;OPRM1;OPRD1;NFKB1 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;NFKB2;NFKB1 GO:0007568| aging CREB1;NFKB2 GO:0048511| rhythmic process CREB1;NFKB2 GO:0006366| transcription from RNA polymerase II promoter NFKB1;ESR1;NFKB2;CREB1 GO:0071260| cellular response to mechanical stimulus TLR4;NFKB1 GO:0045087| innate immune response NFKB1;TLR4;NFKB2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB2;ESR1;NFKB1 GO:0043066| negative regulation of apoptotic process NFKB1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;NFKB2;CREB1;ESR1;NFKB1 GO:0071222| cellular response to lipopolysaccharide NFKB1;OPRK1;TLR4 GO:0006351| transcription, DNA-dependent CREB1;NFKB2;ESR1;NFKB1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;NFKB2;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;ESR1 GO:0006954| inflammatory response NFKB1;TLR4;NFKB2 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;TLR4;NFKB2 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;NFKB1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;ESR1;NFKB2;CREB1 GO:0010629| negative regulation of gene expression NFKB1;ESR1;OPRD1;CREB1 9972:[DB01183 DB06870] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;CREB1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0007165| signal transduction AR;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0006810| transport ABCB1;AR 9973:[DB01183 DB07395] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways GO:0070266| necroptosis TLR4;PYGL GO:0008152| metabolic process UGT1A1;PYGL;CES1 9974:[DB01183 DB08119] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways GO:0007586| digestion UGT1A1;CTRB1 9975:[DB01183 DB07072] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 9976:[DB01183 DB01640] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways GO:0043951| negative regulation of cAMP-mediated signaling PDE3B;OPRM1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;PDE3B;TLR4;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;PDE3B 9977:[DB01183 DB05708] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0006811| ion transport CHRNA7;SLCO1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;TLR4 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0001666| response to hypoxia CHRNA7;CREB1 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C8;UGT1A1 GO:0007613| memory CREB1;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;TLR4 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0070588| calcium ion transmembrane transport CHRNA7;OPRM1 GO:1900273| CHRNA7;CREB1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2E1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CHRNA7;CREB1;TLR4;OPRK1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2C8 GO:0035094| response to nicotine CHRNA7;CREB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA7 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP3A4;CYP2E1;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 9978:[DB01183 DB08843] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08843|GS 0573 SLC22A6 common genes common pathways GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC22A6 9979:[DB01183 DB00383] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;OPRM1;OPRD1;CHRM1;CHRM2 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRM1;CHRM2;OPRK1;CHRM3;CREB1;TLR4 GO:0007586| digestion CHRM3;UGT1A1 9980:[DB01183 DB07613] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 GO:0007626| locomotory behavior HPGDS;OPRM1;OPRK1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;HPGDS;ESR1;OPRM1;OPRD1 9981:[DB01183 DB07261] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07261|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE F10 common genes common pathways 9982:[DB01183 DB06849] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways 9983:[DB01183 DB00616] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00616|Candoxatril MME;ACE common genes common pathways GO:0019233| sensory perception of pain OPRK1;OPRM1;MME;OPRD1 9984:[DB01183 DB08960] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08960|Hexamethonium CHRNA2 common genes common pathways GO:0007165| signal transduction CHRNA2;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;OPRM1 GO:0035094| response to nicotine CHRNA2;CREB1 9985:[DB01183 DB06147] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06147|Sulfathiazole CYP19A1 common genes common pathways GO:0030879| mammary gland development CYP19A1;CREB1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;CYP2C8 GO:0060065| uterus development ESR1;CYP19A1 9986:[DB01183 DB06716] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes ALB common pathways GO:0007268| synaptic transmission OPRM1;OPRD1;GABRB2;OPRK1 GO:0043687| post-translational protein modification ALB GO:1901215| CREB1;GABRB2;GABRB3 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0008152| metabolic process ALPL;UGT1A1;CES1 GO:0032496| response to lipopolysaccharide OPRM1;ALPL;UGT1A1;TLR4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0006811| ion transport SLCO1A2;GABRB3;GABRB2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0007165| signal transduction GABRB3;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0051659| maintenance of mitochondrion location ALB GO:0051384| response to glucocorticoid stimulus UGT1A1;ALPL GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0006810| transport GABRB2;ABCB1;GABRB3 GO:0043069| negative regulation of programmed cell death ALB 9987:[DB01183 DB01662] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways GO:0007586| digestion CTRB1;UGT1A1 9988:[DB01183 DB07350] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;HDAC8;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;HDAC8;CREB1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;HDAC8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;ESR1 9989:[DB01183 DB07849] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0098869| ALB;GSTP1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin GSTP1;CES1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0045471| response to ethanol UGT1A1;GSTP1;OPRK1;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;GSTP1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;GSTP1;CYP2C8 GO:0008152| metabolic process UGT1A1;GSTP1;CES1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 9990:[DB01183 DB11855] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes ABCB1;ALB common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0043069| negative regulation of programmed cell death ALB GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CHRM5;OPRD1;CHRM1;CHRM2;CHRM3;CHRM4;OPRK1 GO:0051659| maintenance of mitochondrion location ALB GO:0045332| phospholipid translocation ABCB1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B3;SLCO1B1 GO:0009267| cellular response to starvation ALB GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0007165| signal transduction CHRM5;OPRM1;OPRD1;ESR1;CHRM1;CHRM2;CHRM3;CREB1;TLR4;CHRM4;OPRK1 GO:0015711| organic anion transport SLCO1B1;SLCO1B3;SLCO1A2 GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0098869| ALB GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;SLCO1B3;SLCO1B1;ABCB1;ABCG2 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0006811| ion transport SLCO1A2;SLCO1B3;SLCO1B1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2;SLCO1B3;SLCO1B1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0007586| digestion UGT1A1;CHRM3 GO:0002576| platelet degranulation ALB GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP3A4;CES1 GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCG2 9991:[DB01183 DB00264] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes ABCB1 common pathways GO:0006811| ion transport SLCO1A2;SLC22A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0055085| transmembrane transport ABCB1;SLC22A2;SLCO1A2 GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP2D6;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;OPRK1;OPRM1;OPRD1;ADRB2 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007165| signal transduction ADRB1;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;ADRB2 GO:0015711| organic anion transport SLC22A2;SLCO1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19 GO:0042493| response to drug CREB1;UGT1A1;ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C8;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2D6;CYP3A4 GO:1901529| ABCB1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;CES1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ADRB2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 9992:[DB01183 DB07007] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0001666| response to hypoxia CREB1;NOS2 GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 GO:0009617| response to bacterium TLR4;NOS2 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0007623| circadian rhythm CREB1;NOS2 GO:0032496| response to lipopolysaccharide NOS2;TLR4;UGT1A1;OPRM1 9993:[DB01183 DB09536] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09536|Titanium dioxide MARCO common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;MARCO GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway MARCO;OPRM1;OPRD1;OPRK1 GO:0006898| receptor-mediated endocytosis MARCO;ALB GO:0002376| immune system process MARCO;TLR4 GO:0045087| innate immune response MARCO;TLR4 9994:[DB01183 DB05253] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05253|Proellex PGR common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;PGR;ESR1 GO:0043401| steroid hormone mediated signaling pathway PGR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TLR4;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PGR GO:0010629| negative regulation of gene expression PGR;CREB1;ESR1;OPRD1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PGR GO:0007165| signal transduction TLR4;CREB1;OPRK1;PGR;ESR1;OPRD1;OPRM1 GO:0030879| mammary gland development PGR;CREB1 9995:[DB01183 DB04418] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways GO:0042594| response to starvation UGT1A1;ADSSL1 GO:0002376| immune system process TLR4;ADSSL1 9996:[DB01183 DB00523] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes ABCB1 common pathways GO:0042573| retinoic acid metabolic process CRABP2;UGT1A1 GO:0008285| negative regulation of cell proliferation RARB;OPRM1;IGFBP3;RARA;RARG GO:0010628| positive regulation of gene expression RARG;RARA;TLR4 GO:1990830| RARG;CREB1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;RXRA GO:0008584| male gonad development RARA;ESR1 GO:0044267| cellular protein metabolic process IGFBP3;ALB GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0007165| signal transduction RARA;CRABP2;CRABP1;ESR1;OPRD1;OPRM1;OPRK1;RARB;TLR4;CREB1 GO:0032689| negative regulation of interferon-gamma production RARA;TLR4 GO:0032720| negative regulation of tumor necrosis factor production RARA;TLR4 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006468| protein phosphorylation RARA;IGFBP3;CREB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0032355| response to estradiol stimulus RARA;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RARB;RXRG;RXRB;RXRA;RARA;RARG;ESR1 GO:0016032| viral reproduction CREB1;RXRA GO:0071391| cellular response to estrogen stimulus ESR1;RARA GO:2001225| regulation of chloride transport ABCB1 GO:0043687| post-translational protein modification ALB;IGFBP3 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP26C1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;RXRA;ESR1;RARA GO:0008361| regulation of cell size CREB1;RARG GO:0006355| regulation of transcription, DNA-dependent ESR1;RARG;CRABP2;RARA;CREB1;RXRA;RXRB;RXRG;RARB GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:0010629| negative regulation of gene expression RARA;OPRD1;ESR1;CREB1 GO:0042981| regulation of apoptotic process CREB1;RARA;IGFBP3;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARB;RXRA;RARA;RARG;ESR1 GO:0043066| negative regulation of apoptotic process RARB;ALB;RARA;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;RXRA;TLR4;CREB1;RARB;RXRG;ESR1;RARA;RARG GO:0071222| cellular response to lipopolysaccharide RARA;TLR4;OPRK1 GO:0043065| positive regulation of apoptotic process RARG;IGFBP3;CREB1;RARB GO:0006351| transcription, DNA-dependent RXRA;RXRB;CREB1;RARB;RXRG;ESR1;RARA;RARG GO:0001889| liver development UGT1A1;RARA GO:0043401| steroid hormone mediated signaling pathway RXRG;RARB;RXRA;RXRB;RARG;RARA;ESR1 GO:0045471| response to ethanol OPRM1;RARA;UGT1A1;OPRK1 GO:1901529| ABCB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;RXRA 9997:[DB01183 DB00259] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0045471| response to ethanol UGT1A1;OPRK1;CYP2E1;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;UGT1A1;CYP3A4;CYP2E1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP2E1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2D6;CYP2C19;CYP2C8 GO:0097267| CYP2C19;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 9998:[DB01183 DB00306] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0000187| activation of MAPK activity TLR4;CHRNA7 GO:0055085| transmembrane transport ABCB1;SLCO1A2;GRIK2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CHRNA7;OPRM1 GO:0009636| response to toxin CES1;GABRB1 GO:0006811| ion transport GABRA2;GABRG1;GABRA3;GABRA5;GABRD;GABRB2;GABRP;GRIA2;CHRNA4;GABRB3;CHRNA7;GABRG3;GABRE;GABRQ;GABRB1;GABRG2;SLCO1A2;GRIK2;GABRA6;GABRA4;GABRA1 GO:0001666| response to hypoxia CHRNA4;CHRNA7;CREB1 GO:0006810| transport ABCB1;GABRA5;GABRA3;GABRB2;GABRD;GABRB3;GABRB1;GABRG2;GABRA4;GABRA6;GRIK2;GABRA1 GO:0007613| memory CREB1;CHRNA7 GO:0007165| signal transduction CHRNA4;GRIA2;GABRB3;CHRNA7;GABRE;OPRM1;GABRB1;OPRD1;GABRQ;GABRA6;ESR1;OPRK1;GABRA5;GABRD;CREB1;GABRP;TLR4 GO:1900273| CHRNA7;CREB1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:1901215| GABRB3;GABRB2;CREB1 GO:0007268| synaptic transmission OPRK1;GABRA5;GABRG1;GABRD;GABRB2;GRIA2;CHRNA4;GABRG2;OPRD1;OPRM1;GRIK2 GO:0042493| response to drug GABRG3;CREB1;UGT1A1;ABCB1 GO:0035094| response to nicotine CREB1;CHRNA7;CHRNA4 GO:0019233| sensory perception of pain OPRM1;OPRD1;CHRNA4;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIK2;OPRM1;CHRNA7;GRIA2;CHRNA4 GO:0007626| locomotory behavior OPRM1;CHRNA4;OPRK1 9999:[DB01183 DB00288] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes CYP3A4 common pathways GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0006351| transcription, DNA-dependent CREB1;NR3C1;ESR1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0045087| innate immune response TLR4;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;ANXA1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0050727| regulation of inflammatory response ANXA1;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process ANXA1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;NR3C1;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug ANXA1;ABCB1;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0006954| inflammatory response ANXA1;TLR4 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;UGT1A1;NR3C1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0032355| response to estradiol stimulus ANXA1;ESR1 GO:0051384| response to glucocorticoid stimulus ANXA1;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ANXA1;OPRD1;OPRM1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction CREB1;TLR4;ANXA1;OPRK1;ESR1;OPRM1;NR3C1;OPRD1 GO:0044849| OPRM1;OPRK1;ANXA1 GO:0002376| immune system process TLR4;ANXA1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;ANXA1 GO:0042359| vitamin D metabolic process CYP3A4 10000:[DB01183 DB08674] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08674|(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FNTA 10001:[DB01183 DB00156] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10;SLCO1A2 10002:[DB01183 DB03095] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03095|Tetramethylammonium Ion GALE common genes common pathways 10003:[DB01183 DB13503] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13503|Tyrothricin ACHE common genes common pathways 10004:[DB01183 DB09279] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09279|Fimasartan AGTR1 common genes common pathways GO:0050727| regulation of inflammatory response TLR4;AGTR1;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;AGTR1;OPRM1;OPRD1;ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;AGTR1;TLR4;CREB1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;AGTR1 GO:0050729| positive regulation of inflammatory response TLR4;AGTR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;AGTR1;OPRM1;OPRD1 10005:[DB01183 DB03124] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways GO:0014070| response to organic cyclic compound CASP3;UGT1A1 GO:0010033| response to organic substance CREB1;UGT1A1;CASP3 GO:0001666| response to hypoxia CREB1;CASP3 GO:0032355| response to estradiol stimulus CASP3;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CASP3 GO:0035094| response to nicotine CREB1;CASP3 GO:0097190| apoptotic signaling pathway CASP3;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;CASP3;TLR4;UGT1A1 GO:0042060| wound healing CASP3;OPRM1 GO:0043065| positive regulation of apoptotic process CASP3;CREB1 GO:0043066| negative regulation of apoptotic process ALB;CASP3 10006:[DB01183 DB08626] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08626|Thiorphan MME common genes common pathways GO:0019233| sensory perception of pain OPRD1;MME;OPRM1;OPRK1 10007:[DB01183 DB05115] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05115|NN344 INSR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;INSR GO:0006355| regulation of transcription, DNA-dependent CREB1;INSR;ESR1 GO:0008584| male gonad development INSR;ESR1 GO:0000187| activation of MAPK activity TLR4;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;INSR;TLR4 GO:0071363| cellular response to growth factor stimulus INSR;CREB1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;INSR;OPRD1;OPRM1 GO:0007613| memory CREB1;INSR GO:0006468| protein phosphorylation INSR;CREB1 10008:[DB01183 DB08345] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08345|4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0007165| signal transduction ESR1;CSNK2A1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0048511| rhythmic process CREB1;CSNK2A1 GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CSNK2A1;CREB1 10009:[DB01183 DB06042] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1;TUBB4A GO:0007409| axonogenesis CREB1;TOP2B GO:0048511| rhythmic process TOP2A;CREB1 GO:0007411| axon guidance CREB1;TUBB3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;TOP2A;CREB1;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0042752| regulation of circadian rhythm TOP2A;CREB1 10010:[DB01183 DB01832] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01832|4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid FAH common genes common pathways GO:0008152| metabolic process CES1;FAH;UGT1A1 10011:[DB01183 DB03425] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential GRIK2;OPRM1 GO:0007268| synaptic transmission OPRK1;GRIK2;OPRD1;OPRM1 GO:0006810| transport ABCB1;GRIK2 GO:0006811| ion transport GRIK2;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;GRIK2;ABCB1 10012:[DB01183 DB08060] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways GO:0051384| response to glucocorticoid stimulus AGXT;UGT1A1 10013:[DB01183 DB05264] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05264|NPI 32101 CSF2RB common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;TLR4;CSF2RB;UGT1A1 GO:0044267| cellular protein metabolic process ALB;CSF2RB GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CSF2RB;CREB1;TLR4 10014:[DB01183 DB01742] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways GO:0016032| viral reproduction CREB1;PPIA 10015:[DB01183 DB00750] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00750|Prilocaine SCN5A common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SCN5A;ABCB1 GO:0006811| ion transport SCN5A;SLCO1A2 10016:[DB01183 DB05849] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05849|NCX 950 ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;ADRB2 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;ADRB2;ESR1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0016579| protein deubiquitination ESR1;ADRB2 GO:1904646| ADRB2;TLR4 10017:[DB01183 DB03470] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03470|Trypanothione TPR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;ESR1 GO:0016032| viral reproduction CREB1;TPR 10018:[DB01183 DB08510] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08510|5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0042742| defense response to bacterium TLR4;IGHG2 GO:0045087| innate immune response TLR4;IGHG2 GO:0002376| immune system process IGHG2;TLR4 10019:[DB01183 DB04445] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0007586| digestion SULT2A1;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;SULT2A1 GO:0008202| steroid metabolic process SULT2A1;CYP3A4;CYP2C8;UGT1A1 10020:[DB01183 DB04133] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0009636| response to toxin SLC22A8;CES1 GO:0006811| ion transport SLCO1A2;SLC22A8;SLC22A5;SLC22A11 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A11;SLC22A5;SLC22A8;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1A2;SLC22A8;SLC22A11 GO:0015711| organic anion transport SLC22A6;SLC22A11;SLCO1A2;SLC22A5 10021:[DB01183 DB04934] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04934|Rifalazil rpoB;CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 10022:[DB01183 DB00751] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes CYP3A4;ABCB1 common pathways GO:0002933| CYP2C8;CYP3A4 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1;HTR2A GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR7;OPRD1;OPRM1;HRH2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0045332| phospholipid translocation ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;UGT1A1;CYP2D6;CYP2C8 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;HRH1;OPRM1;HTR2A;HRH2;HTR7;ADRA1A;OPRK1;ADRA2A GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0007568| aging ADRA1A;CREB1;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1 GO:0006810| transport ABCB1 GO:0007613| memory HRH1;HTR2A;HRH2;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;ADRA1A GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction ADRA2A;OPRK1;ADRA1A;HTR7;CREB1;TLR4;ESR1;HRH2;HTR2A;OPRM1;HRH1;OPRD1 GO:0007610| behavior HTR2A;OPRK1 GO:0017144| drug metabolic process UGT1A1;CYP2B6;CYP2C8;CYP2D6;CYP3A4 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;ADRA1A;HTR2A GO:0007268| synaptic transmission HTR7;OPRK1;OPRD1;OPRM1;HTR2A GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C8;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6;CYP2B6 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0016032| viral reproduction CREB1;HTR2A GO:0006955| immune response OPRK1;TLR4;OPRD1;HRH2 GO:0006954| inflammatory response TLR4;HRH1 GO:0008542| visual learning CREB1;HRH1;HRH2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0007623| circadian rhythm CREB1;HTR7 GO:1901529| ABCB1 GO:0019233| sensory perception of pain OPRD1;OPRM1;HTR2A;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1;HRH1;OPRK1;ADRA1A GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C8;CYP2D6;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 10023:[DB01183 DB01537] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01537|4-Bromo-2,5-dimethoxyphenethylamine HTR2C;HTR2A common genes common pathways GO:0007165| signal transduction CREB1;TLR4;HTR2C;OPRK1;ESR1;HTR2A;OPRM1;OPRD1 GO:0007610| behavior HTR2A;HTR2C;OPRK1 GO:0007568| aging HTR2A;CREB1 GO:0007613| memory HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRD1;OPRM1;OPRK1;HTR2C GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2C;TLR4;HTR2A;OPRM1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0007626| locomotory behavior OPRM1;OPRK1;HTR2C GO:0019233| sensory perception of pain OPRM1;OPRD1;HTR2A;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1;HTR2C;OPRK1 GO:0016032| viral reproduction HTR2A;CREB1 GO:0007268| synaptic transmission HTR2C;OPRK1;OPRM1;OPRD1;HTR2A GO:0042493| response to drug HTR2A;HTR2C;ABCB1;CREB1;UGT1A1 10024:[DB01183 DB00621] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression TLR4;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0016579| protein deubiquitination AR;ESR1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 GO:0006810| transport ABCB1;AR GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0097267| CYP2C9;CYP2C8 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;AR GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;TLR4;CREB1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C9;CYP2C8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development ESR1;AR GO:0006629| lipid metabolic process CYP2C9;CYP3A4 10025:[DB01183 DB08972] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08972|Flumequine CYP1A2 common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 10026:[DB01183 DB00765] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00765|Metyrosine TH common genes common pathways GO:0042493| response to drug TH;CREB1;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;TH;CYP2C8 GO:0035094| response to nicotine CREB1;TH GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;TH GO:0045471| response to ethanol TH;OPRM1;OPRK1;UGT1A1 GO:0007626| locomotory behavior TH;OPRM1;OPRK1 GO:0070848| response to growth factor stimulus OPRM1;TH GO:0042755| eating behavior OPRD1;OPRM1;TH;OPRK1 GO:0014070| response to organic cyclic compound TH;UGT1A1 GO:0001666| response to hypoxia TH;CREB1 GO:0014823| response to activity CREB1;TH GO:0071363| cellular response to growth factor stimulus OPRD1;TH;CREB1 GO:0032355| response to estradiol stimulus ESR1;TH GO:0007613| memory CREB1;TH GO:0048545| response to steroid hormone stimulus UGT1A1;TH 10027:[DB01183 DB05824] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05824|CNS-5161 GRIN1 common genes common pathways GO:0019233| sensory perception of pain OPRK1;OPRM1;GRIN1;OPRD1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIN1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;TLR4;CREB1 GO:0043065| positive regulation of apoptotic process GRIN1;CREB1 GO:0008542| visual learning GRIN1;CREB1 GO:0043278| response to morphine GRIN1;OPRM1;OPRK1 GO:0007613| memory CREB1;GRIN1 GO:0006811| ion transport GRIN1;SLCO1A2 GO:0008344| adult locomotory behavior OPRD1;GRIN1 GO:1904646| TLR4;GRIN1 GO:1903428| TLR4;GRIN1 10028:[DB01183 DB01109] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PF4;OPRK1 GO:0072089| stem cell proliferation FGF2;ABCB1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;PF4 GO:0030154| cell differentiation CREB1;FGF4;FGF2;FGF1 GO:0006468| protein phosphorylation FGFR4;CREB1;FGFR2;FGFR1 GO:0031100| organ regeneration HGF;UGT1A1 GO:0010863| positive regulation of phospholipase C activity FGF2;ESR1;FGFR1 GO:0032715| negative regulation of interleukin-6 production TLR4;HGF GO:0035729| cellular response to hepatocyte growth factor stimulus HGF;CREB1 GO:0007165| signal transduction TLR4;CREB1;FGF4;OPRK1;OPRD1;FGF2;OPRM1;ESR1;FGF1 GO:0007409| axonogenesis FGFR2;CREB1 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGFR4;FGF4;TLR4;FGFR2;FGF19;FGF2;OPRM1 GO:0030855| epithelial cell differentiation FGFR2;CES1 GO:0000187| activation of MAPK activity FGF1;FGF2;TLR4;HGF GO:0044267| cellular protein metabolic process ALB;SERPINC1 GO:1990830| FGF4;CREB1 GO:0010628| positive regulation of gene expression TLR4;PF4;FGFR4;FGF4 GO:0060523| prostate epithelial cord elongation ESR1;FGFR2 GO:0007584| response to nutrient UGT1A1;SERPINC1 GO:0042060| wound healing HPSE;OPRM1;FGF2;FGFR2 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1;FGFR2 GO:0032496| response to lipopolysaccharide TLR4;PF4;UGT1A1;FGFR2;SELP;OPRM1 GO:0045471| response to ethanol OPRM1;FGFR2;UGT1A1;OPRK1 GO:0046330| positive regulation of JNK cascade FGF19;TLR4 GO:0006351| transcription, DNA-dependent CREB1;FGFR1;ESR1 GO:0001889| liver development UGT1A1;HGF GO:0002576| platelet degranulation SELP;ALB;HGF;PF4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;FGF1;FGF2;FGFR2;TLR4;CREB1;PF4;HGF;FGF4 GO:0050829| defense response to Gram-negative bacterium TLR4;SELP GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;FGFR2 GO:0043066| negative regulation of apoptotic process HGF;ALB;FGF4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR2;ESR1;FGFR1 GO:0032733| positive regulation of interleukin-10 production TLR4;HGF GO:0010572| positive regulation of platelet activation TLR4;SELP GO:0010629| negative regulation of gene expression CREB1;FGFR1;ESR1;OPRD1;FGF19 GO:0006355| regulation of transcription, DNA-dependent ESR1;FGFR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;FGF2;ESR1 GO:0043687| post-translational protein modification SERPINC1;ALB GO:0006954| inflammatory response SELP;TLR4;PF4 GO:0006955| immune response OPRD1;TLR4;PF4;OPRK1 GO:0007595| lactation CREB1;SERPINC1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;PF4 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;FGFR2 10029:[DB01183 DB03988] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;ADCYAP1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ADCYAP1;OPRM1;ESR1 GO:0021983| pituitary gland development ADCYAP1;CREB1 GO:0032755| positive regulation of interleukin-6 production TLR4;ADCYAP1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ADCYAP1;OPRM1;TLR4 GO:0010628| positive regulation of gene expression TLR4;ADCYAP1 GO:0045471| response to ethanol OPRM1;ADCYAP1;UGT1A1;OPRK1 GO:0019233| sensory perception of pain OPRK1;OPRD1;ADCYAP1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADCYAP1;ESR1;CREB1;TLR4 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;ADCYAP1;OPRK1 GO:0042594| response to starvation UGT1A1;ADCYAP1 GO:0071385| cellular response to glucocorticoid stimulus ADCYAP1;UGT1A1 10030:[DB01183 DB00805] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0007626| locomotory behavior DRD2;HTR2C;OPRK1;DRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;DRD2;TLR4;CREB1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;OPRM1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0048148| behavioral response to cocaine HTR2A;DRD1;DRD2;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2C;HTR2B;OPRK1;OPRM1;OPRD1;ESR1;HTR2A GO:0045471| response to ethanol OPRM1;UGT1A1;DRD2;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HTR2B GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HTR2B GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0019233| sensory perception of pain OPRK1;HTR2A;OPRM1;OPRD1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0008542| visual learning CREB1;DRD2;DRD1 GO:0043278| response to morphine OPRK1;DRD2;OPRM1 GO:0035094| response to nicotine CREB1;DRD2 GO:0042711| maternal behavior OPRK1;DRD1 GO:0016032| viral reproduction CREB1;HTR2A GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;MAOA GO:0007268| synaptic transmission HTR2C;OPRK1;HTR2A;OPRM1;OPRD1 GO:0042493| response to drug ABCB1;DRD2;HTR2B;HTR2C;UGT1A1;CREB1;DRD1;SLC6A4;HTR2A GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0007165| signal transduction DRD1;OPRM1;OPRD1;ESR1;CHRM1;HTR2A;DRD2;HTR2C;HTR2B;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0007610| behavior HTR2B;HTR2C;OPRK1;HTR2A GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:1900273| CREB1;DRD2 GO:0007613| memory HTR2A;DRD1;SLC6A4;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007568| aging CREB1;HTR2A GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0014002| astrocyte development DRD1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway DRD2;OPRK1;HTR2B;HTR2C;OPRD1;OPRM1;HTR2A;CHRM1;DRD1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;DRD1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0010033| response to organic substance SLC6A4;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;CREB1 GO:0010628| positive regulation of gene expression SLC6A4;DRD1;TLR4 GO:0001666| response to hypoxia SLC6A4;DRD2;CREB1 GO:0055085| transmembrane transport SLCO1A2;SLC6A4;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;DRD2;HTR2C;HTR2B;TLR4 GO:0042220| response to cocaine OPRM1;DRD1;DRD2;OPRK1 GO:0007409| axonogenesis CREB1;DRD2 GO:0009636| response to toxin CES1;SLC6A4;DRD2 10031:[DB01183 DB11793] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP1;CREB1 GO:0071294| cellular response to zinc ion PARP1;CREB1 GO:0006351| transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0008152| metabolic process GUSB;CES1;UGT1A1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0006366| transcription from RNA polymerase II promoter ESR1;PARP1;CREB1 GO:1904646| TLR4;PARP1 10032:[DB01183 DB03316] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway TGFB3;CREB1 GO:0000187| activation of MAPK activity TGFB3;TLR4 GO:0030879| mammary gland development CREB1;TGFB3 GO:0043627| response to estrogen stimulus OPRK1;ESR1;TGFB3 GO:0008285| negative regulation of cell proliferation OPRM1;TGFB3 GO:0030890| positive regulation of B cell proliferation TLR4;TNFSF13B GO:0001666| response to hypoxia CREB1;TGFB3 GO:0007568| aging CREB1;TGFB3 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TNFSF13B;TLR4;CREB1 GO:0002376| immune system process TNFSF13B;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;TGFB3;CREB1 GO:0006955| immune response OPRK1;TNFSF13B;TLR4;OPRD1 GO:0042060| wound healing OPRM1;TGFB3 GO:0042981| regulation of apoptotic process ESR1;TGFB3;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TGFB3;ESR1;CREB1;TLR4 GO:0002576| platelet degranulation ALB;TGFB3 GO:0043065| positive regulation of apoptotic process CREB1;TGFB3 10033:[DB01183 DB06185] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06185|Forodesine PNP common genes common pathways GO:0042493| response to drug CREB1;PNP;UGT1A1;ABCB1 GO:0006955| immune response OPRD1;TLR4;PNP;OPRK1 10034:[DB01183 DB01445] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01445|Bufotenine MAOA;MAOB common genes common pathways GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0009636| response to toxin CES1;MAOB GO:0045471| response to ethanol MAOB;UGT1A1;OPRK1;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;MAOB;TLR4 GO:0055114| oxidation-reduction process MAOA;CYP3A4;MAOB;CYP2C8 GO:0042493| response to drug ABCB1;UGT1A1;MAOB;CREB1 10035:[DB01183 DB00374] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;P2RY12;PTGIR;OPRK1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0030154| cell differentiation CREB1;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;P2RY12;OPRK1 GO:0070588| calcium ion transmembrane transport P2RY12;OPRM1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0007165| signal transduction P2RY12;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4;PTGIR GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1;CYP2C9 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARD GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;PTGIR GO:0010033| response to organic substance CREB1;UGT1A1;PPARD GO:0014823| response to activity CREB1;PPARD GO:0042060| wound healing PPARD;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARD GO:0032496| response to lipopolysaccharide OPRM1;PTGIR;TLR4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0043401| steroid hormone mediated signaling pathway PPARD;ESR1 GO:0006351| transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;PPARD GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0006629| lipid metabolic process CYP3A4;PPARD;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PPARD GO:0045893| positive regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0043491| protein kinase B signaling cascade P2RY12;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARD GO:0051924| regulation of calcium ion transport OPRD1;P2RY12 10036:[DB01183 DB08445] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10037:[DB01183 DB05875] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;OPRM1;TLR4;UGT1A1 GO:0019233| sensory perception of pain OPRK1;PTGS2;OPRM1;OPRD1 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response TLR4;PTGS2;ESR1 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0060065| uterus development ESR1;CYP19A1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0042493| response to drug CREB1;UGT1A1;BCHE;ABCB1;PTGS2 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8;CYP19A1 GO:0006954| inflammatory response TLR4;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0007613| memory PTGS2;CREB1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007568| aging PTGS2;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TLR4 GO:0098869| PTGS2;ALB GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1;PTGS2 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 10038:[DB01183 DB06989] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06989|{4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways 10039:[DB01183 DB04880] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04880|Enoximone PDE3A common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;PDE3A;CREB1 GO:0043066| negative regulation of apoptotic process PDE3A;ALB GO:0071560| cellular response to transforming growth factor beta stimulus PDE3A;CREB1 GO:0006629| lipid metabolic process CYP3A4;PDE3A GO:0007165| signal transduction PDE3A;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway PDE3A;OPRK1;OPRM1;OPRD1 10040:[DB01183 DB08801] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08801|Dimetindene HRH1;CHRM2 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;HRH1;ESR1;CHRM2;OPRK1;CREB1;TLR4 GO:0007613| memory HRH1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CHRM2;OPRM1;OPRD1;HRH1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HRH1;ESR1;OPRK1 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response HRH1;TLR4 10041:[DB01183 DB06932] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways GO:0006468| protein phosphorylation PDPK1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PDPK1 GO:0006351| transcription, DNA-dependent CREB1;PDPK1;ESR1 10042:[DB01183 DB01762] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways GO:0006811| ion transport SLCO1A2;SLC5A8 GO:0055085| transmembrane transport SLC16A1;SLC16A7;SLCO1A2;ABCB1;SLC5A8;SLC16A3 GO:0008152| metabolic process CES1;FAH;UGT1A1 GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0032094| response to food SLC16A1;OPRM1 10043:[DB01183 DB02089] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02089|CP-526423 PYGL common genes common pathways GO:0070266| necroptosis TLR4;PYGL GO:0008152| metabolic process UGT1A1;PYGL;CES1 10044:[DB01183 DB00527] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SCN5A;CALM1;SCN10A;ABCB1 GO:0006811| ion transport SCN10A;SLCO1A2;SCN5A GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0007186| G-protein coupled receptor signaling pathway CALM1;OPRD1;OPRM1;OPRK1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0042493| response to drug BCHE;UGT1A1;CREB1;ABCB1 GO:0007600| sensory perception OPRM1;OPRK1;SCN10A GO:0019233| sensory perception of pain OPRM1;OPRD1;SCN10A;OPRK1 GO:0002576| platelet degranulation ALB;CALM1 10045:[DB01183 DB00253] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;NR3C1;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;NR3C1;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;NR3C1;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 10046:[DB01183 DB05386] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0044267| cellular protein metabolic process CSF2RA;ALB GO:0042493| response to drug ABCB1;BCHE;UGT1A1;CREB1 10047:[DB01183 DB03430] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03430|(2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile LCTL common genes common pathways 10048:[DB01183 DB05429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05429|CAT-213 CCL11 common genes common pathways GO:0006954| inflammatory response CCL11;TLR4 GO:0006955| immune response CCL11;OPRD1;OPRK1;TLR4 GO:0009314| response to radiation CCL11;OPRM1;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CCL11;TLR4 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;CCL11 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CCL11;OPRM1;OPRD1 GO:0006468| protein phosphorylation CCL11;CREB1 10049:[DB01183 DB06127] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06127|Bisegliptin DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10050:[DB01183 DB07574] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07574|2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE STMN4;TUBB2B;TUBA1A;TUBA1C;TUBA1B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBA1A 10051:[DB01183 DB09051] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09051|Elosulfase alfa GALNS common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;GALNS 10052:[DB01183 DB06781] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06781|Difluprednate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;TLR4;CREB1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0042737| drug catabolic process CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;NR3C1;OPRM1;ESR1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter ESR1;NR3C1;CREB1 10053:[DB01183 DB01615] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01615|Aceprometazine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;TLR4 GO:0008542| visual learning HRH1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;HRH1;ESR1 GO:0007165| signal transduction HRH1;OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;HRH1;OPRD1 GO:0007613| memory CREB1;HRH1 10054:[DB01183 DB02800] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways GO:1990830| CREB1;SHMT1 10055:[DB01183 DB04931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04931|Afamelanotide MC1R common genes common pathways GO:0032720| negative regulation of tumor necrosis factor production TLR4;MC1R GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;MC1R;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;MC1R GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger MC1R;OPRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MC1R;CREB1;TLR4;ESR1 10056:[DB01183 DB09151] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09151|Flutemetamol (18F) APP common genes common pathways GO:0042346| positive regulation of NF-kappaB import into nucleus APP;TLR4 GO:0002576| platelet degranulation APP;ALB GO:0043065| positive regulation of apoptotic process APP;CREB1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0007626| locomotory behavior OPRK1;APP;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;TLR4;CREB1;ESR1 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:1990090| APP;CREB1 GO:0045087| innate immune response TLR4;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;ESR1 GO:0046330| positive regulation of JNK cascade APP;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;ESR1 GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TLR4 GO:0008542| visual learning APP;CREB1 GO:0007268| synaptic transmission OPRD1;OPRM1;APP;OPRK1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;APP GO:1901215| CREB1;APP GO:0043687| post-translational protein modification ALB;APP GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;APP;TLR4 GO:1900273| CREB1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;APP GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;APP;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRK1;OPRD1;OPRM1 GO:0006468| protein phosphorylation CREB1;APP GO:0007613| memory APP;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration APP;ESR1;OPRM1 GO:1904646| TLR4;APP GO:0010628| positive regulation of gene expression APP;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;APP GO:1903223| APP;TLR4 GO:0007409| axonogenesis CREB1;APP GO:0000187| activation of MAPK activity APP;TLR4 GO:0008344| adult locomotory behavior OPRD1;APP GO:0044267| cellular protein metabolic process ALB;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;TLR4;OPRM1 10057:[DB01183 DB05945] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways GO:0007165| signal transduction ANTXR1;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 10058:[DB01183 DB07815] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways GO:0008152| metabolic process CES1;AADACL2;UGT1A1 10059:[DB01183 DB03478] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways 10060:[DB01183 DB01481] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01481|1-Testosterone AR common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;AR GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0007165| signal transduction OPRK1;CREB1;TLR4;AR;ESR1;OPRM1;OPRD1 GO:0006810| transport ABCB1;AR 10061:[DB01183 DB01892] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0098869| PTGS1;ALB GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;NR1I2;OPRK1 GO:0015711| organic anion transport SLCO1B1;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;NR1I2;CYP2C8 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0006810| transport ABCB1;ABCC2 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1A2;ALB GO:0010628| positive regulation of gene expression NR1I2;TLR4 GO:0043627| response to estrogen stimulus OPRK1;ABCC2;ESR1 GO:0006811| ion transport SLCO1B1;SLCO1A2 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport SLCO1B1;SLCO1A2;ABCC2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;NR1I2;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABCC2;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;NR1I2;PTGS1;CES1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0033762| response to glucagon stimulus ABCC2;CREB1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ABCC2;OPRM1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR1I2 GO:0006351| transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0006954| inflammatory response PTGS1;ALOX5;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCC2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NR1I2 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I2;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;CYP3A4;CYP2C8 10062:[DB01183 DB01141] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01141|Micafungin COMT;ARSA common genes common pathways GO:0043627| response to estrogen stimulus ESR1;COMT;OPRK1 GO:0014070| response to organic cyclic compound COMT;UGT1A1 GO:0051930| regulation of sensory perception of pain OPRK1;COMT;OPRD1;OPRM1 GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0043687| post-translational protein modification ARSA;ALB GO:0042493| response to drug ABCB1;UGT1A1;COMT;CREB1 GO:0008152| metabolic process UGT1A1;CES1;ARSA GO:0032496| response to lipopolysaccharide OPRM1;TLR4;COMT;UGT1A1 10063:[DB01183 DB07183] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07183|N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB GO:0016032| viral reproduction KDR;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;KDR;CREB1 GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0030154| cell differentiation KDR;CREB1 GO:0006468| protein phosphorylation CREB1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;TLR4 10064:[DB01183 DB06804] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response TLR4;PTGS2;ESR1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;OPRK1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;UGT1A1;TLR4 GO:0006954| inflammatory response TLR4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;PTGS2;OPRM1 GO:0098869| PTGS2;ALB GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory PTGS2;CREB1 GO:0007568| aging CREB1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 10065:[DB01183 DB08678] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08678|(4-ETHYLPHENYL)SULFAMIC ACID PTPRB common genes common pathways 10066:[DB01183 DB00826] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00826|Natamycin CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 10067:[DB01183 DB04820] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0042493| response to drug ABCB1;MAOB;COMT;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8;MAOB GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0032496| response to lipopolysaccharide OPRM1;MAOB;COMT;UGT1A1;TLR4 GO:0045471| response to ethanol OPRK1;MAOB;UGT1A1;OPRM1 GO:0009636| response to toxin CES1;MAOB GO:0014070| response to organic cyclic compound COMT;UGT1A1 GO:0051930| regulation of sensory perception of pain OPRK1;COMT;OPRM1;OPRD1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;COMT GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 10068:[DB01183 DB07182] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 10069:[DB01183 DB02008] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PCK1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;PCK1 GO:0071456| cellular response to hypoxia PCK1;OPRD1 GO:0007568| aging CREB1;PCK1 GO:0014823| response to activity PCK1;CREB1 GO:0032868| response to insulin stimulus PCK1;OPRK1 10070:[DB01183 DB06754] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06754|Danaparoid SERPINC1 common genes common pathways GO:0043687| post-translational protein modification SERPINC1;ALB GO:0007595| lactation SERPINC1;CREB1 GO:0044267| cellular protein metabolic process ALB;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0007584| response to nutrient SERPINC1;UGT1A1 10071:[DB01183 DB07537] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07537|N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR GO:0016032| viral reproduction CREB1;KDR GO:0010629| negative regulation of gene expression CREB1;KDR;OPRD1;ESR1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0006468| protein phosphorylation CREB1;KDR GO:0030154| cell differentiation CREB1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR 10072:[DB01183 DB07486] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07486|3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline ITGAL common genes common pathways GO:0006954| inflammatory response TLR4;ITGAL GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;ITGAL 10073:[DB01183 DB13346] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;TLR4;UGT1A1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;HDAC6;HDAC10 GO:0019233| sensory perception of pain OPRK1;OPRM1;PTGS2;OPRD1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0070848| response to growth factor stimulus OPRM1;HDAC6 GO:0050727| regulation of inflammatory response TLR4;PTGS2;ESR1 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;HDAC10 GO:0042493| response to drug PTGS2;ABCB1;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;HDAC6;HDAC10 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0006954| inflammatory response TLR4;PTGS1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0007568| aging CREB1;PTGS2 GO:0007613| memory PTGS2;CREB1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0098869| PTGS2;PTGS1;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0009636| response to toxin CES1;HDAC6 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;CREB1;PTGS2;HDAC6 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 10074:[DB01183 DB08129] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08129|(1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol PNMT common genes common pathways 10075:[DB01183 DB00099] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00099|Filgrastim CSF3R;ELANE common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;ELANE;UGT1A1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ELANE;ESR1 GO:0042742| defense response to bacterium TLR4;ELANE GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;ELANE GO:0007165| signal transduction OPRK1;CSF3R;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ELANE 10076:[DB01183 DB04326] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04326|Dihydroxyacetone phosphate ALDOA;TPI1;ALDOB;fucA common genes common pathways GO:0008152| metabolic process TPI1;CES1;UGT1A1 GO:0002576| platelet degranulation ALDOA;ALB 10077:[DB01183 DB03546] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways GO:0008152| metabolic process CES1;GART;UGT1A1 GO:0010033| response to organic substance UGT1A1;GART;CREB1 10078:[DB01183 DB00287] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00287|Travoprost PTGFR common genes common pathways GO:0010628| positive regulation of gene expression PTGFR;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;PTGFR GO:0032355| response to estradiol stimulus PTGFR;ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;PTGFR;CREB1;TLR4;OPRK1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;PTGFR;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;PTGFR 10079:[DB01183 DB01378] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01378|Magnesium cation ATP1A1 common genes common pathways GO:0006811| ion transport ATP1A1;SLCO1A2 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ATP1A1 GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 10080:[DB01183 DB13931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0006468| protein phosphorylation ROCK1;ROCK2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway ROCK2;ROCK1;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ROCK1;OPRD1;OPRM1;ESR1 GO:0007249| I-kappaB kinase/NF-kappaB cascade ROCK1;ROCK2;TLR4 GO:0048511| rhythmic process ROCK2;CREB1 GO:0010628| positive regulation of gene expression ROCK2;TLR4;ROCK1 GO:0042752| regulation of circadian rhythm CREB1;ROCK2 10081:[DB01183 DB04837] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04837|Clofedanol HRH1 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;HRH1;OPRD1;OPRM1 GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;HRH1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;HRH1;OPRD1;ESR1;OPRK1 GO:0008542| visual learning HRH1;CREB1 GO:0006954| inflammatory response HRH1;TLR4 10082:[DB01183 DB05161] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0032496| response to lipopolysaccharide MPO;OPRM1;ELANE;UGT1A1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ELANE;ESR1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0055114| oxidation-reduction process CYP2C8;MPO;CYP3A4 GO:0042742| defense response to bacterium MPO;ELANE;TLR4 GO:0032094| response to food OPRM1;MPO GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;ELANE GO:0007568| aging MPO;CREB1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ELANE 10083:[DB01183 DB07692] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07692|1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine PKM common genes common pathways GO:0031100| organ regeneration PKM;UGT1A1 GO:0001666| response to hypoxia CREB1;PKM GO:0007584| response to nutrient UGT1A1;PKM GO:0010033| response to organic substance PKM;UGT1A1;CREB1 GO:0032868| response to insulin stimulus OPRK1;PKM GO:0008152| metabolic process UGT1A1;CES1;PKM GO:0001889| liver development UGT1A1;PKM 10084:[DB01183 DB00179] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways GO:0006954| inflammatory response TLR4;ALOX5 GO:0055114| oxidation-reduction process ALOX5;CYP2J2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2J2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2J2;CYP2C8 10085:[DB01183 DB08950] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08950|Indoramin ADRA1A common genes common pathways GO:0007165| signal transduction ADRA1A;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ESR1;OPRM1 GO:0007568| aging ADRA1A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRA1A;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;OPRM1;OPRD1;ESR1 GO:0042493| response to drug ADRA1A;ABCB1;CREB1;UGT1A1 10086:[DB01183 DB07879] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC4;CREB1;TLR4;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;HDAC4 GO:0071260| cellular response to mechanical stimulus HDAC4;TLR4 GO:0006351| transcription, DNA-dependent CREB1;HDAC4;ESR1 GO:0006954| inflammatory response TLR4;HDAC4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC4 GO:0006355| regulation of transcription, DNA-dependent HDAC4;CREB1;ESR1 GO:0042493| response to drug HDAC4;CREB1;UGT1A1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;HDAC4;CREB1 GO:0006338| chromatin remodeling ESR1;HDAC4 GO:1903428| HDAC4;TLR4 GO:0008285| negative regulation of cell proliferation HDAC4;OPRM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC4 10087:[DB01183 DB07453] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;CREB1;UGT1A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 10088:[DB01183 DB02179] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0044267| cellular protein metabolic process TTR;ALB 10089:[DB01183 DB03747] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways GO:0008152| metabolic process UGT1A1;HEXB;CES1 GO:0007626| locomotory behavior HEXB;OPRM1;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;HEXB;CREB1;TLR4 GO:0044267| cellular protein metabolic process ALB;HEXB 10090:[DB01183 DB06819] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CES1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 10091:[DB01183 DB07668] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways GO:0007586| digestion UGT1A1;CTRB1 10092:[DB01183 DB07383] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways GO:0007586| digestion CTRB1;UGT1A1 10093:[DB01183 DB05304] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05304|WX-G250 CA9;IL2 common genes common pathways GO:0050729| positive regulation of inflammatory response IL2;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;IL2;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration IL2;OPRM1;ESR1 GO:0002376| immune system process TLR4;IL2 GO:0030890| positive regulation of B cell proliferation IL2;TLR4 GO:0001666| response to hypoxia CREB1;CA9 GO:0032729| positive regulation of interferon-gamma production TLR4;IL2 GO:0045471| response to ethanol OPRK1;IL2;UGT1A1;OPRM1 GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IL2;TLR4;CREB1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CA9 GO:0006955| immune response OPRD1;TLR4;IL2;OPRK1 10094:[DB01183 DB00419] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00419|Miglustat UGCG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;UGCG 10095:[DB01183 DB01763] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;NNT 10096:[DB01183 DB00155] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0042742| defense response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP3A4;NOS2;NOS1;CYP2C8;NOS3 GO:0009617| response to bacterium NOS2;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NOS1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PADI4;CREB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;OTC GO:0010629| negative regulation of gene expression OPRD1;ESR1;NOS2;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NOS1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;PADI4 GO:0001889| liver development OTC;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;NOS2;TLR4;UGT1A1 GO:0007623| circadian rhythm ASS1;NOS2;CREB1 GO:0045087| innate immune response PADI4;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0043066| negative regulation of apoptotic process DDAH2;ALB GO:0030520| intracellular estrogen receptor signaling pathway ESR1;PADI2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;NOS1;ESR1 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC22A6 GO:0032868| response to insulin stimulus OTC;OPRK1 GO:0008285| negative regulation of cell proliferation NOS3;DDAH1;OPRM1 GO:0001666| response to hypoxia CREB1;NOS1;NOS2 GO:1990830| PADI2;CREB1 GO:0006338| chromatin remodeling ESR1;PADI4 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB GO:0071363| cellular response to growth factor stimulus OPRD1;NOS1;CREB1 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;DDAH1;DDAH2;ASS1;OPRM1;ESR1 GO:0002376| immune system process TLR4;PADI4 10097:[DB01183 DB07096] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07096|6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE PARP1 common genes common pathways GO:0006366| transcription from RNA polymerase II promoter PARP1;ESR1;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:1904646| TLR4;PARP1 GO:0006351| transcription, DNA-dependent CREB1;PARP1;ESR1 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;PARP1;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;ESR1;CREB1 10098:[DB01183 DB08813] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0010628| positive regulation of gene expression TLR4;MYC GO:0048146| positive regulation of fibroblast proliferation ESR1;MYC GO:0007584| response to nutrient UGT1A1;SERPINC1 GO:0016579| protein deubiquitination MYC;ESR1 GO:0014070| response to organic cyclic compound UGT1A1;FOS GO:0009636| response to toxin FOS;CES1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0006366| transcription from RNA polymerase II promoter CREB1;FOS;MYC;ESR1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FOS GO:0044267| cellular protein metabolic process ALB;SERPINC1 GO:0032870| cellular response to hormone stimulus FOS;UGT1A1 GO:0006338| chromatin remodeling ESR1;MYC GO:0071456| cellular response to hypoxia MYC;OPRD1 GO:0007568| aging CREB1;FOS GO:0006954| inflammatory response TLR4;FOS;SELP GO:0007595| lactation CREB1;SERPINC1 GO:0042493| response to drug MYC;ABCB1;UGT1A1;FOS;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;FOS;MYC;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;FOS;MYC GO:0043687| post-translational protein modification ALB;SERPINC1 GO:0045672| positive regulation of osteoclast differentiation CREB1;FOS GO:0002576| platelet degranulation SELP;ALB GO:0070848| response to growth factor stimulus MYC;OPRM1 GO:0050829| defense response to Gram-negative bacterium SELP;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;FOS;CREB1;MYC;ESR1 GO:0043066| negative regulation of apoptotic process ALB;MYC GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;MYC GO:0010572| positive regulation of platelet activation SELP;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter FOS;MYC;ESR1 GO:0032496| response to lipopolysaccharide OPRM1;SELP;FOS;TLR4;UGT1A1 GO:0006351| transcription, DNA-dependent CREB1;MYC;ESR1 10099:[DB01183 DB01091] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01091|Butenafine SQLE common genes common pathways GO:0055114| oxidation-reduction process SQLE;CYP3A4;CYP2C8 GO:0006695| cholesterol biosynthetic process CES1;SQLE GO:0010033| response to organic substance SQLE;UGT1A1;CREB1 10100:[DB01183 DB07003] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0001666| response to hypoxia NOS2;CREB1 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0071222| cellular response to lipopolysaccharide TLR4;NOS2;OPRK1 GO:0007623| circadian rhythm CREB1;NOS2 GO:0032496| response to lipopolysaccharide NOS2;TLR4;UGT1A1;OPRM1 GO:0009617| response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 10101:[DB01183 DB00055] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0002576| platelet degranulation ALB;F5;PF4;F8;SERPINE1;PROS1 GO:0050829| defense response to Gram-negative bacterium TLR4;SERPINE1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;SERPINE1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PF4;TLR4;CREB1;ESR1;SERPINE1 GO:0007623| circadian rhythm CREB1;SERPINE1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;PF4;THBD;OPRM1 GO:0006953| acute-phase response F2;UGT1A1;F8 GO:0032760| positive regulation of tumor necrosis factor production TLR4;PF4 GO:0006955| immune response OPRD1;PF4;TLR4;OPRK1 GO:0006954| inflammatory response PF4;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CP;F8;CYP2C8 GO:0043687| post-translational protein modification CP;ALB;F5 GO:0007165| signal transduction THBD;ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0032757| positive regulation of interleukin-8 production TLR4;SERPINE1 GO:0050729| positive regulation of inflammatory response SERPINE1;TLR4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;PF4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PF4;F2;OPRK1 GO:0010628| positive regulation of gene expression TLR4;PF4 GO:0044267| cellular protein metabolic process ALB;F5;F2;CP GO:0006811| ion transport SLCO1A2;CP 10102:[DB01183 DB12340] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways GO:0097190| apoptotic signaling pathway TLR4;BAD GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;BAD GO:0071260| cellular response to mechanical stimulus TLR4;BAD GO:0042981| regulation of apoptotic process CREB1;BCL2L2;BCL2;BAD;ESR1 GO:0043066| negative regulation of apoptotic process ALB;BCL2L2;BCL2 GO:0043065| positive regulation of apoptotic process CREB1;BAD GO:0009314| response to radiation OPRM1;BCL2;OPRK1 GO:0042493| response to drug BAD;BCL2;CREB1;UGT1A1;ABCB1 GO:0051607| defense response to virus OPRK1;BCL2 GO:0035094| response to nicotine CREB1;BCL2 GO:0051924| regulation of calcium ion transport OPRD1;BCL2 GO:0040018| positive regulation of multicellular organism growth BCL2;CREB1 GO:0071456| cellular response to hypoxia OPRD1;BCL2;BAD GO:0032355| response to estradiol stimulus BAD;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2;BAD GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BCL2 GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0051881| regulation of mitochondrial membrane potential BCL2;OPRD1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;BCL2 GO:0009636| response to toxin CES1;BCL2 GO:0014070| response to organic cyclic compound BAD;UGT1A1 GO:0007409| axonogenesis CREB1;BCL2 GO:0010033| response to organic substance UGT1A1;CREB1;BAD GO:0008285| negative regulation of cell proliferation OPRM1;BCL2 GO:0001666| response to hypoxia CREB1;BAD GO:0030890| positive regulation of B cell proliferation TLR4;BCL2 GO:0008584| male gonad development ESR1;BCL2 10103:[DB01183 DB04606] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0031100| organ regeneration UGT1A1;F7 GO:0032355| response to estradiol stimulus F7;ESR1 GO:0043627| response to estrogen stimulus F7;OPRK1;ESR1 GO:0001666| response to hypoxia CREB1;F7 GO:0014070| response to organic cyclic compound UGT1A1;F7 GO:0007623| circadian rhythm CREB1;F7 10104:[DB01183 DB04890] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04890|Bepotastine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;TLR4 GO:0008542| visual learning HRH1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;HRH1;OPRD1;OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;HRH1;ESR1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;HRH1;OPRK1 GO:0007613| memory HRH1;CREB1 10105:[DB01183 DB07992] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB 10106:[DB01183 DB03101] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03101|Ribose-1-Phosphate PNP common genes common pathways GO:0042493| response to drug UGT1A1;PNP;CREB1;ABCB1 GO:0006955| immune response OPRD1;OPRK1;TLR4;PNP 10107:[DB01183 DB08055] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0006468| protein phosphorylation LCK;CREB1 GO:0016032| viral reproduction CREB1;LCK GO:0042493| response to drug UGT1A1;CREB1;ABCB1;LCK GO:0045087| innate immune response TLR4;LCK 10108:[DB01183 DB01776] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01776|M-Cresol INS common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;INS GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;INS GO:0006953| acute-phase response INS;UGT1A1 GO:0046889| positive regulation of lipid biosynthetic process INS;CREB1 GO:0042060| wound healing OPRM1;INS GO:0051000| positive regulation of nitric-oxide synthase activity INS;ESR1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;INS GO:0044267| cellular protein metabolic process ALB;INS GO:0010628| positive regulation of gene expression TLR4;INS GO:0032460| negative regulation of protein oligomerization OPRD1;INS GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;INS;OPRK1 GO:1900273| CREB1;INS GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1;INS 10109:[DB01183 DB09087] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09087|Potassium alum ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 10110:[DB01183 DB07342] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0043627| response to estrogen stimulus OPRK1;HMOX1;ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HMOX1 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0001666| response to hypoxia HMOX1;CREB1 GO:0071456| cellular response to hypoxia OPRD1;HMOX1 GO:0042167| heme catabolic process UGT1A1;HMOX1 GO:0035094| response to nicotine HMOX1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HMOX1 GO:0043065| positive regulation of apoptotic process HMOX1;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HMOX1 10111:[DB01183 DB04377] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04377|Meglutol HMGCR common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;HMGCR GO:0032874| positive regulation of stress-activated MAPK cascade TLR4;HMGCR GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0006629| lipid metabolic process HMGCR;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;HMGCR;CYP2C8 GO:0008542| visual learning CREB1;HMGCR GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP2C8;UGT1A1 GO:0007568| aging HMGCR;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;TLR4 GO:0007584| response to nutrient HMGCR;UGT1A1 10112:[DB01183 DB08206] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 10113:[DB01183 DB03010] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes CYP3A4 common pathways GO:0002933| CYP3A4;CYP2C8 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4A;TUBA4A;TUBB4B;TUBB;TUBA1A GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007411| axon guidance CREB1;TUBB3 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0002576| platelet degranulation ALB;TUBA4A GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 10114:[DB01183 DB02147] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways GO:0006954| inflammatory response C3;TLR4 GO:0006955| immune response TLR4;OPRK1;OPRD1;C3 GO:0043687| post-translational protein modification ALB;C3 GO:0045087| innate immune response C3;TLR4 GO:0006629| lipid metabolic process C3;CYP3A4 GO:0044267| cellular protein metabolic process C3;ALB GO:0007165| signal transduction ESR1;C3;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0002376| immune system process TLR4;C3 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;C3;OPRM1;OPRD1 10115:[DB01183 DB04106] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04106|Fotemustine TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process TXNRD1;CYP3A4;CYP2C8 GO:0098869| ALB;TXNRD1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;TXNRD1 10116:[DB01183 DB00032] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00032|Menotropins FSHR;LHCGR common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LHCGR;ESR1;OPRM1;OPRD1;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;LHCGR GO:0008584| male gonad development FSHR;ESR1;LHCGR GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;FSHR GO:0007165| signal transduction OPRM1;OPRD1;LHCGR;ESR1;FSHR;CREB1;TLR4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;FSHR;OPRD1;OPRM1;LHCGR 10117:[DB01183 DB01672] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01672|2,3-Dihydroxy-Benzoic Acid LCN2 common genes common pathways GO:0002376| immune system process TLR4;LCN2 GO:0006811| ion transport LCN2;SLCO1A2 GO:0045087| innate immune response TLR4;LCN2 10118:[DB01183 DB11652] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11652|Tucatinib ERBB2 common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;ERBB2;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;ESR1 GO:0042060| wound healing OPRM1;ERBB2 GO:0006355| regulation of transcription, DNA-dependent ERBB2;ESR1;CREB1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;ERBB2;TLR4;CREB1;OPRK1 GO:0006468| protein phosphorylation ERBB2;CREB1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;ERBB2 GO:0010628| positive regulation of gene expression ERBB2;TLR4 10119:[DB01183 DB02141] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02141|S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process CYP3A4;NOS3;CYP2C8 10120:[DB01183 DB08615] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways 10121:[DB01183 DB13158] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13158|Clobetasone NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;TLR4;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006351| transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;NR3C1;OPRD1;ESR1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 10122:[DB01183 DB04112] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04112|1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide PLA2G2A common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;PLA2G2A;OPRM1 GO:0050729| positive regulation of inflammatory response PLA2G2A;TLR4 GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 10123:[DB01183 DB02097] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02097|Cytidine UCK2 common genes common pathways GO:0008152| metabolic process UCK2;UGT1A1;CES1 10124:[DB01183 DB14042] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14042|Galcanezumab CALCA;CALCB common genes common pathways GO:0050829| defense response to Gram-negative bacterium CALCA;TLR4 GO:0045087| innate immune response TLR4;CALCA GO:0045671| negative regulation of osteoclast differentiation CALCA;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CALCA;CALCB;OPRK1 GO:0006468| protein phosphorylation CREB1;CALCA GO:0032757| positive regulation of interleukin-8 production TLR4;CALCA GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;CALCB 10125:[DB01183 DB05416] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:1901215| CREB1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent PPARA;ESR1;PPARD;CREB1 GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;PPARA;ESR1 GO:0042752| regulation of circadian rhythm PPARA;CREB1 GO:0043401| steroid hormone mediated signaling pathway PPARA;ESR1;PPARD GO:0006351| transcription, DNA-dependent CREB1;PPARA;ESR1;PPARD GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0042060| wound healing OPRM1;PPARD;PPARA GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0006629| lipid metabolic process PPARA;CYP3A4;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA;PPARD GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARA;TLR4;CREB1 GO:0071222| cellular response to lipopolysaccharide PPARD;TLR4;OPRK1 GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0010033| response to organic substance UGT1A1;CREB1;PPARD GO:0014823| response to activity PPARD;CREB1 GO:0048511| rhythmic process PPARA;CREB1 GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0001666| response to hypoxia PPARA;CREB1 GO:0045600| positive regulation of fat cell differentiation PPARD;CREB1 GO:0030154| cell differentiation CREB1;PPARD GO:0071456| cellular response to hypoxia PPARD;OPRD1 10126:[DB01183 DB05993] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05993|PRX-07034 HTR6 common genes common pathways GO:0007165| signal transduction HTR6;OPRK1;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR6;OPRD1;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR6;OPRM1;OPRD1 GO:0007268| synaptic transmission HTR6;OPRK1;OPRM1;OPRD1 10127:[DB01183 DB13914] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13914|Volixibat SLC10A2 common genes common pathways GO:0006810| transport ABCB1;SLC10A2 GO:0015721| bile acid and bile salt transport SLC10A2;ALB;SLCO1A2 GO:0006811| ion transport SLC10A2;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC10A2 10128:[DB01183 DB03317] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYCS;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4;CES1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0097267| CYP2C8;CYP2C9 10129:[DB01183 DB04027] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04027|D-Arginine CKM common genes common pathways 10130:[DB01183 DB06433] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0008152| metabolic process RRM1;UGT1A1;TYMP;CES1 GO:0055114| oxidation-reduction process CYP2C8;RRM1;CYP3A4 GO:0030154| cell differentiation TYMP;CREB1 GO:0008584| male gonad development RRM1;ESR1 10131:[DB01183 DB04516] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process ISYNA1;CYP3A4 10132:[DB01183 DB06727] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06727|Sparteine CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 10133:[DB01183 DB00406] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00406|Gentian violet cation SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLC22A1 GO:0015711| organic anion transport SLC22A1;SLCO1A2 10134:[DB01183 DB05309] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05309|TP-508 FGF4 common genes common pathways GO:0030154| cell differentiation CREB1;FGF4 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;FGF4 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF4;TLR4;OPRM1 GO:1990830| CREB1;FGF4 GO:0010628| positive regulation of gene expression TLR4;FGF4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;FGF4 GO:0043066| negative regulation of apoptotic process FGF4;ALB 10135:[DB01183 DB03621] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03621|L-709,587 FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport FKBP1A;OPRM1 GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A 10136:[DB01183 DB12212] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12212|Landiolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 10137:[DB01183 DB05050] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05050|ADL5859 OPRD1 common genes OPRD1 common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1 GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0006955| immune response OPRD1;OPRK1;TLR4 GO:0051924| regulation of calcium ion transport OPRD1 GO:0097237| OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1 GO:0071456| cellular response to hypoxia OPRD1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0042755| eating behavior OPRM1;OPRD1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1 GO:0008344| adult locomotory behavior OPRD1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1 10138:[DB01183 DB00929] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways GO:0006955| immune response TLR4;PTGER4;OPRK1;OPRD1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGER4;TLR4;OPRM1;PTGER2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;PTGER3;ESR1 GO:0071260| cellular response to mechanical stimulus PTGER4;TLR4 GO:0050729| positive regulation of inflammatory response PTGER4;TLR4 GO:0007186| G-protein coupled receptor signaling pathway PTGER2;OPRM1;PTGER3;OPRD1;OPRK1;PTGER4 GO:0007165| signal transduction OPRK1;TLR4;CREB1;PTGER4;PTGER2;ESR1;OPRD1;PTGER3;OPRM1 10139:[DB01183 DB01270] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01270|Ranibizumab VEGFA common genes common pathways GO:0007595| lactation VEGFA;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;VEGFA;CREB1 GO:0043066| negative regulation of apoptotic process ALB;VEGFA GO:0002576| platelet degranulation VEGFA;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;VEGFA;ESR1 GO:1900745| VEGFA;OPRK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0060749| mammary gland alveolus development VEGFA;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0001666| response to hypoxia CREB1;VEGFA GO:0010628| positive regulation of gene expression VEGFA;TLR4 GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;VEGFA;OPRM1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA GO:0030154| cell differentiation VEGFA;CREB1 GO:0071456| cellular response to hypoxia VEGFA;OPRD1 10140:[DB01183 DB01581] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01581|Sulfamerazine ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 10141:[DB01183 DB07246] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways GO:0043065| positive regulation of apoptotic process MMP9;CREB1 GO:0043066| negative regulation of apoptotic process MMP9;ALB 10142:[DB01183 DB08810] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0007610| behavior OPRK1;HTR1A;HTR2A GO:0007165| signal transduction ESR1;HTR1A;HTR2A;HTR4;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0007568| aging CREB1;HTR2A GO:0007613| memory HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR1A;HTR2A;OPRM1;HTR4;OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;HTR4;OPRM1 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;HTR2A GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1;OPRK1 GO:0016032| viral reproduction CREB1;HTR2A GO:0042493| response to drug ABCB1;UGT1A1;CREB1;HTR2A GO:0007268| synaptic transmission OPRM1;HTR4;OPRD1;HTR2A;OPRK1 10143:[DB01183 DB09033] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09033|Vedolizumab ITGA4;ITGB7 common genes common pathways 10144:[DB01183 DB01000] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0015711| organic anion transport SLC22A5;SLCO1A2 GO:0006811| ion transport SLC15A2;SLC22A5;SLCO1A2;SLC15A1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLCO1A2;SLC15A2;SLC22A5 GO:0007586| digestion SLC15A1;UGT1A1 10145:[DB01183 DB00847] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0048545| response to steroid hormone stimulus SST;UGT1A1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;NPY2R;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;NPY2R;SST;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration NPY2R;OPRM1;ESR1 GO:0007568| aging MPO;NPY2R;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1;NPY2R GO:0030818| negative regulation of cAMP biosynthetic process NPY2R;OPRM1 GO:0007584| response to nutrient UGT1A1;SST GO:0008285| negative regulation of cell proliferation OPRM1;SST GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;NPY2R;OPRK1 GO:0007218| neuropeptide signaling pathway NPY2R;OPRK1;OPRD1;OPRM1 GO:0007626| locomotory behavior OPRK1;NPY2R;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0033603| positive regulation of dopamine secretion OPRK1;NPY2R GO:0007586| digestion UGT1A1;SST GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;MPO;OPRM1 GO:0042493| response to drug SST;ABCB1;UGT1A1;CREB1 GO:0007268| synaptic transmission SST;OPRD1;OPRM1;OPRK1;NPY2R GO:0032094| response to food MPO;OPRM1 GO:0042742| defense response to bacterium TLR4;MPO GO:0055114| oxidation-reduction process CYP2C8;MPO;CYP3A4 10146:[DB01183 DB07029] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways GO:0001666| response to hypoxia NOS2;CREB1 GO:0009617| response to bacterium TLR4;NOS2 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8 GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide NOS2;TLR4;UGT1A1;OPRM1 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0071222| cellular response to lipopolysaccharide NOS2;TLR4;OPRK1 10147:[DB01183 DB06939] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10148:[DB01183 DB06162] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06162|Lumiliximab FCER2 common genes common pathways GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;FCER2 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;FCER2 10149:[DB01183 DB04270] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0030855| epithelial cell differentiation CES1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0048511| rhythmic process PPARG;CREB1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation UGT1A1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0042493| response to drug UGT1A1;CREB1;PPARG;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG 10150:[DB01183 DB08186] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08186|(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE KAT2B common genes common pathways GO:0016579| protein deubiquitination ESR1;KAT2B GO:0008285| negative regulation of cell proliferation KAT2B;OPRM1 GO:0048511| rhythmic process KAT2B;CREB1 GO:0006338| chromatin remodeling KAT2B;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent KAT2B;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;KAT2B GO:0006367| transcription initiation from RNA polymerase II promoter KAT2B;ESR1 GO:0016032| viral reproduction CREB1;KAT2B GO:0006351| transcription, DNA-dependent ESR1;KAT2B;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;KAT2B;TLR4;CREB1 10151:[DB01183 DB06268] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;EDNRB;TLR4;UGT1A1 GO:0007194| negative regulation of adenylate cyclase activity EDNRB;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2C19 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;EDNRB;OPRK1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1;EDNRB GO:0071222| cellular response to lipopolysaccharide OPRK1;EDNRB;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2C9;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8 GO:0043066| negative regulation of apoptotic process EDNRB;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;EDNRB GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19;CYP2C9 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;EDNRA;EDNRB;OPRK1 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2C8;CYP2C19;CYP3A4 GO:0007204| elevation of cytosolic calcium ion concentration EDNRB;EDNRA;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1;EDNRA GO:0007568| aging EDNRB;CREB1 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;EDNRA;CREB1;TLR4;EDNRB;OPRK1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2C9;UGT1A1;CYP3A4 GO:0097267| CYP2C8;CYP2C19;CYP2C9 GO:0051930| regulation of sensory perception of pain OPRK1;EDNRB;OPRM1;OPRD1 GO:0002933| CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound EDNRB;UGT1A1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0001666| response to hypoxia EDNRA;CREB1 GO:0009822| alkaloid catabolic process CYP3A4 10152:[DB01183 DB06097] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06097|GSK-923295 CENPE common genes common pathways 10153:[DB01183 DB09459] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;HIF1AN;CREB1 GO:0055114| oxidation-reduction process CYP3A4;HIF1AN;CYP2C8 GO:0006351| transcription, DNA-dependent HIF1AN;CREB1;ESR1 10154:[DB01183 DB08200] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08200|(1R)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE;UGT1A1;CREB1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 10155:[DB01183 DB05787] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05787|LM-609 ITGB3 common genes common pathways GO:0016032| viral reproduction CREB1;ITGB3 GO:0002576| platelet degranulation ITGB3;ALB GO:0042060| wound healing OPRM1;ITGB3 10156:[DB01183 DB08884] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0015711| organic anion transport SLCO1A2;SLCO1B1;SLCO1B3 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0006810| transport ABCC3;ABCC2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC3 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;SLCO1A2;ALB GO:0010033| response to organic substance ABCC4;CREB1;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;ABCC2;OPRK1 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;SLCO1B3;ALB;ABCC3 GO:0055085| transmembrane transport ABCC3;ABCB1;ABCC2;SLCO1A2;SLCO1B3;SLCO1B1;ABCC4 GO:0006855| drug transmembrane transport ABCC3;ABCC2;ABCB1 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0006811| ion transport SLCO1A2;SLCO1B3;SLCO1B1 GO:0033762| response to glucagon stimulus ABCC2;CREB1 GO:0071222| cellular response to lipopolysaccharide ABCC2;OPRK1;TLR4 GO:0002576| platelet degranulation ABCC4;ALB GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1;TLR4;OPRM1 GO:0055114| oxidation-reduction process ABCC4;CYP3A4;CYP2C8 GO:0042493| response to drug ABCC4;UGT1A1;CREB1;ABCB1;ABCC2 10157:[DB01183 DB12712] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12712|Pilsicainide ABCB11 common genes common pathways GO:0006810| transport ABCB11;ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB11;ABCB1 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;ALB 10158:[DB01183 DB12961] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARA GO:0006351| transcription, DNA-dependent PPARA;ESR1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;LTB4R;OPRM1;OPRD1;OPRK1;LTB4R2 GO:0042060| wound healing PPARA;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity LTB4R2;OPRM1 GO:0006629| lipid metabolic process PPARA;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;PPARA GO:0007218| neuropeptide signaling pathway OPRD1;LTB4R;OPRM1;LTB4R2;OPRK1 GO:1901215| CREB1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;PPARA GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARA;ESR1 GO:0042752| regulation of circadian rhythm CREB1;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARA GO:0006955| immune response OPRD1;LTB4R;OPRK1;TLR4 GO:0006954| inflammatory response TLR4;LTB4R GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;LTB4R;OPRK1;LTB4R2 GO:0007165| signal transduction ESR1;LTB4R;OPRM1;OPRD1;OPRK1;LTB4R2;CREB1;TLR4 GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0048511| rhythmic process PPARA;CREB1 GO:0001666| response to hypoxia PPARA;CREB1 10159:[DB01183 DB05458] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1;CHRNA4 GO:0008542| visual learning CHRNB2;CREB1 GO:0035094| response to nicotine CHRNB2;CREB1;CHRNA4 GO:0019233| sensory perception of pain OPRM1;OPRD1;CHRNA4;CHRNB2;OPRK1 GO:0045471| response to ethanol OPRK1;CHRNB2;UGT1A1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA4;OPRM1;CHRNB2 GO:0007626| locomotory behavior OPRM1;CHRNA4;CHRNB2;OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1;CHRNB2 GO:0006811| ion transport CHRNB2;SLCO1A2;CHRNA4 GO:0042220| response to cocaine OPRM1;CHRNB2;OPRK1 GO:0001666| response to hypoxia CHRNB2;CREB1;CHRNA4 GO:0030890| positive regulation of B cell proliferation TLR4;CHRNB2 GO:0007613| memory CREB1;CHRNB2 GO:0007165| signal transduction CHRNA4;OPRD1;OPRM1;ESR1;OPRK1;CHRNB2;TLR4;CREB1 10160:[DB01183 DB05190] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05190|XL281 BRAF;RAF1 common genes common pathways GO:1990090| CREB1;BRAF GO:0042981| regulation of apoptotic process ESR1;RAF1;CREB1 GO:0043066| negative regulation of apoptotic process ALB;BRAF;RAF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;RAF1 GO:0042060| wound healing RAF1;OPRM1 GO:0008542| visual learning BRAF;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation RAF1;OPRD1;BRAF GO:0007165| signal transduction ESR1;OPRM1;RAF1;OPRD1;OPRK1;BRAF;CREB1;TLR4 GO:0006468| protein phosphorylation CREB1;BRAF;RAF1 GO:0030154| cell differentiation CREB1;BRAF;RAF1 GO:0008285| negative regulation of cell proliferation RAF1;OPRM1 GO:0001666| response to hypoxia RAF1;CREB1 GO:0010628| positive regulation of gene expression BRAF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;RAF1;TLR4;BRAF 10161:[DB01183 DB08609] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08609|(2R)-N-{4-[Ethyl(phenyl)sulfamoyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide PDK2 common genes common pathways GO:0006468| protein phosphorylation CREB1;PDK2 10162:[DB01183 DB01437] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0007165| signal transduction GABRA5;TLR4;GABRP;CREB1;GABRD;OPRK1;GABRQ;GABRB1;OPRD1;OPRM1;GABRE;ESR1;GABRA6;GABRB3 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4;CYP11A1 GO:0006810| transport GABRB3;GABRA1;GABRA4;GABRA6;GABRB1;GABRG2;ABCB1;GABRB2;GABRD;GABRA3;GABRA5 GO:0042359| vitamin D metabolic process CYP11A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0009636| response to toxin GABRB1;CES1 GO:0006811| ion transport GABRG3;GABRB3;GABRA1;GABRA6;GABRA4;SLCO1A2;GABRG2;GABRB1;GABRQ;GABRE;GABRA2;GABRP;GABRB2;GABRD;GABRA5;GABRA3;GABRG1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP11A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007268| synaptic transmission OPRM1;OPRD1;GABRG2;GABRB2;GABRD;GABRG1;GABRA5;OPRK1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;GABRG3 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4;CYP11A1 GO:1901215| GABRB3;CREB1;GABRB2 10163:[DB01183 DB06778] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes ALB common pathways GO:0002576| platelet degranulation SOD1;ALB GO:0043065| positive regulation of apoptotic process CREB1;SOD1 GO:0007626| locomotory behavior OPRM1;SOD1;OPRK1 GO:0008152| metabolic process UGT1A1;PAH;TYR;CES1 GO:0043066| negative regulation of apoptotic process SOD1;ALB GO:0045471| response to ethanol OPRM1;SOD1;OPRK1;UGT1A1;MAOB GO:0042060| wound healing LOX;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;MAOB;TLR4;OPRM1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0055114| oxidation-reduction process CP;TYR;LOX;MAOA;CYP3A4;SOD1;CYP2C8;MAOB;MT-CO1;PAH GO:0043687| post-translational protein modification CP;ALB GO:0042493| response to drug ABCB1;CREB1;UGT1A1;MAOB;SOD1;LOX GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB;LOX GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0007568| aging CREB1;MT-CO1;SOD1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0010033| response to organic substance CREB1;UGT1A1;SOD1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0000187| activation of MAPK activity TLR4;SOD1 GO:0001895| retina homeostasis ALB;SOD1 GO:0044267| cellular protein metabolic process CP;ALB GO:0006811| ion transport CP;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0009636| response to toxin CES1;MAOB 10164:[DB01183 DB01038] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways GO:0007613| memory DRD1;CREB1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0014002| astrocyte development DRD1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;DRD1;DRD5;OPRM1;OPRD1 GO:0007165| signal transduction OPRK1;DRD2;CREB1;TLR4;DRD1;DRD5;ESR1;OPRM1;OPRD1 GO:1900273| CREB1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;DRD2;TLR4 GO:0042220| response to cocaine DRD2;OPRK1;DRD5;DRD1;OPRM1 GO:0007409| axonogenesis CREB1;DRD2 GO:0009636| response to toxin CES1;DRD2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;DRD1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0001666| response to hypoxia CREB1;DRD2 GO:0010628| positive regulation of gene expression TLR4;DRD1 GO:0045471| response to ethanol OPRM1;OPRK1;DRD2;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0042060| wound healing DRD5;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;DRD2 GO:0007626| locomotory behavior OPRK1;DRD2;OPRM1;DRD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD5;DRD1 GO:0048148| behavioral response to cocaine DRD1;DRD2;OPRK1 GO:0007268| synaptic transmission DRD5;OPRM1;OPRD1;OPRK1 GO:0042493| response to drug DRD2;ABCB1;CREB1;UGT1A1;DRD1 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0008542| visual learning DRD2;CREB1;DRD1 GO:0043278| response to morphine OPRM1;DRD2;OPRK1 GO:0035094| response to nicotine DRD2;CREB1 GO:0042711| maternal behavior DRD1;OPRK1 10165:[DB01183 DB09028] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0007626| locomotory behavior CHRNB2;CHRNA3;OPRK1;OPRM1;CHRNA4 GO:0033603| positive regulation of dopamine secretion OPRK1;CHRNB2 GO:0045471| response to ethanol OPRM1;UGT1A1;CHRNB2;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;CHRNA4;CHRNA6;OPRM1;CHRNA3;CHRNB2 GO:0019233| sensory perception of pain OPRD1;OPRM1;CHRNA4;CHRNB2;OPRK1 GO:0008542| visual learning CHRNB2;CREB1 GO:0035094| response to nicotine CHRNB2;CREB1;CHRNA4;CHRNA7;CHRNA6 GO:0007268| synaptic transmission CHRNA4;OPRD1;OPRM1;CHRNA6;OPRK1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:1900273| CHRNA7;CREB1 GO:0007165| signal transduction CHRNA7;CHRNA4;ESR1;CHRNA6;OPRM1;OPRD1;OPRK1;CHRNA3;CREB1;TLR4;CHRNB2 GO:0007613| memory CREB1;CHRNB2;CHRNA7 GO:0006810| transport CHRNA6;ABCB1 GO:0001666| response to hypoxia CHRNA4;CHRNA7;CHRNB2;CREB1 GO:0030890| positive regulation of B cell proliferation TLR4;CHRNB2 GO:0006811| ion transport CHRNB2;CHRNA3;CHRNA6;SLCO1A2;CHRNA7;CHRNA4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CHRNA7;TLR4 GO:0042220| response to cocaine OPRM1;CHRNB2;OPRK1 GO:0000187| activation of MAPK activity TLR4;CHRNA7 10166:[DB01183 DB08234] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHFR GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 10167:[DB01183 DB05777] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways GO:0044267| cellular protein metabolic process F2;F5;ALB GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;F2 GO:0006953| acute-phase response UGT1A1;F2 GO:0043687| post-translational protein modification ALB;F5 GO:0002576| platelet degranulation F5;ALB 10168:[DB01183 DB03351] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03351|Sri-9439 DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity DHFR;ESR1 GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 10169:[DB01183 DB00937] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0007268| synaptic transmission OPRD1;OPRM1;SLC6A2;OPRK1 GO:0042493| response to drug CREB1;SLC6A2;UGT1A1;SLC6A3;ABCB1 GO:0007595| lactation CREB1;SLC6A3 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;SLC6A3 GO:0007626| locomotory behavior SLC6A3;OPRK1;OPRM1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3;SLCO1A2 GO:0042220| response to cocaine OPRK1;SLC6A3;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging CREB1;SLC6A3 GO:0006810| transport SLC6A2;ABCB1 10170:[DB01183 DB01199] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01199|Tubocurarine CHRNA2;HTR3A;ACHE;CHRNA7;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0007165| signal transduction CHRNA7;CHRNA2;ESR1;OPRD1;OPRM1;OPRK1;HTR3A;TLR4;CREB1 GO:0015711| organic anion transport SLC22A1;SLC22A2;SLCO1A2 GO:1900273| CREB1;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0007613| memory CHRNA7;CREB1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0071363| cellular response to growth factor stimulus CREB1;HTR3A;OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient BCHE;UGT1A1 GO:0001666| response to hypoxia CHRNA7;CREB1 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0042220| response to cocaine OPRM1;HTR3A;OPRK1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CHRNA7;TLR4 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1;SLCO1A2 GO:0006811| ion transport HTR3A;SLC22A2;SLC22A1;CHRNA2;CHRNA7;SLCO1A2 GO:0045471| response to ethanol OPRK1;HTR3A;UGT1A1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;CHRNA7;OPRM1 GO:0035094| response to nicotine CREB1;CHRNA7;CHRNA2 GO:0007268| synaptic transmission OPRM1;OPRD1;HTR3A;OPRK1 GO:0042493| response to drug CREB1;BCHE;UGT1A1;ABCB1 10171:[DB01183 DB09067] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CRHR1;OPRD1;OPRM1 GO:0007165| signal transduction OPRM1;OPRD1;CRHR1;ESR1;CREB1;TLR4;OPRK1 GO:0006955| immune response OPRK1;TLR4;OPRD1;CRHR1 10172:[DB01183 DB08605] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DECR1 GO:0006629| lipid metabolic process CYP3A4;DECR1 10173:[DB01183 DB05934] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05934|CTCE-0214 CXCL12 common genes common pathways GO:0006955| immune response CXCL12;OPRD1;TLR4;OPRK1 GO:0051924| regulation of calcium ion transport OPRD1;CXCL12 GO:0009314| response to radiation CXCL12;OPRM1;OPRK1 GO:0033603| positive regulation of dopamine secretion CXCL12;OPRK1 GO:0008344| adult locomotory behavior CXCL12;OPRD1 GO:0001666| response to hypoxia CREB1;CXCL12 GO:0007411| axon guidance CREB1;CXCL12 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CXCL12;OPRM1;OPRD1 GO:0031100| organ regeneration UGT1A1;CXCL12 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;CXCL12;ESR1 10174:[DB01183 DB06408] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0017144| drug metabolic process NT5C2;CYP3A4;CYP2C8;UGT1A1 GO:0006898| receptor-mediated endocytosis ALB;ENPP1 GO:0006955| immune response OPRD1;ENPP1;TLR4;OPRK1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;IMPDH1 GO:0008152| metabolic process ENPP1;UGT1A1;CES1;NT5C2 10175:[DB01183 DB05260] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0007165| signal transduction OPRK1;IL1B;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0032757| positive regulation of interleukin-8 production IL1B;TLR4 GO:0006898| receptor-mediated endocytosis TFRC;TFR2;ALB GO:0032755| positive regulation of interleukin-6 production TLR4;IL1B GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;IL1B;ESR1;OPRM1 GO:0044267| cellular protein metabolic process TF;ALB GO:0001895| retina homeostasis TF;ALB GO:0000187| activation of MAPK activity IL1B;TLR4 GO:0006811| ion transport ATP6V1B2;TF;SLCO1A2 GO:0008285| negative regulation of cell proliferation OPRM1;IL1B GO:1990830| TFRC;CREB1 GO:0030890| positive regulation of B cell proliferation TLR4;TFRC GO:0010628| positive regulation of gene expression TLR4;IL1B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;TLR4 GO:0046330| positive regulation of JNK cascade TLR4;IL1B GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;IL1B GO:0032729| positive regulation of interferon-gamma production IL1B;TLR4 GO:0071260| cellular response to mechanical stimulus IL1B;TLR4 GO:1900745| OPRK1;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;CREB1;TLR4;TFR2;ESR1 GO:0002576| platelet degranulation TF;ALB GO:0031663| lipopolysaccharide-mediated signaling pathway IL1B;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus IL1B;TLR4 GO:0055114| oxidation-reduction process RRM2;CYP2C8;CYP3A4 GO:0043687| post-translational protein modification ALB;TF GO:0043491| protein kinase B signaling cascade IL1B;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;IL1B GO:0006953| acute-phase response UGT1A1;TFR2 GO:0006954| inflammatory response TLR4;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;ESR1 GO:0016032| viral reproduction TFRC;CREB1 GO:0006955| immune response TLR4;IL1B;OPRK1;OPRD1 10176:[DB01183 DB04977] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2E1;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP4A11 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0045471| response to ethanol OPRM1;CYP2E1;UGT1A1;OPRK1 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CES1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP4A11;CYP2E1;CYP2A6 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2A6;CYP2E1;CYP3A4;CYP4A11 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP2E1 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP2C8 10177:[DB01183 DB05931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05931|Pegdinetanib KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR GO:0030154| cell differentiation CREB1;KDR GO:0006468| protein phosphorylation CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0010629| negative regulation of gene expression KDR;CREB1;ESR1;OPRD1 GO:0016032| viral reproduction CREB1;KDR GO:0043066| negative regulation of apoptotic process ALB;KDR 10178:[DB01183 DB01520] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways GO:0006810| transport ABCB1;GRIN2C;GRIN2A;GRIN2B GO:0007613| memory CREB1;GRIN2A;CHRNA7 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRNA7;CREB1;TLR4;OPRK1 GO:1900273| GRIN2A;CHRNA7;CREB1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7;GRIN3A;GRIN3B GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0008344| adult locomotory behavior OPRD1;GRIN2D GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;TLR4 GO:0006811| ion transport CHRNA7;GRIN2A;GRIN2B;GRIN2D;SLCO1A2;GRIN3B;GRIN3A;GRIN2C GO:0051930| regulation of sensory perception of pain OPRK1;GRIN2A;OPRM1;GRIN2D;OPRD1 GO:1904646| GRIN2A;TLR4 GO:0001666| response to hypoxia CREB1;CHRNA7 GO:0019233| sensory perception of pain OPRD1;OPRM1;GRIN2A;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2A;CHRNA7;GRIN2B;GRIN2D;OPRM1;GRIN3B;GRIN3A;GRIN2C GO:0045471| response to ethanol OPRK1;GRIN3A;UGT1A1;GRIN2A;GRIN2B;OPRM1 GO:0043065| positive regulation of apoptotic process CREB1;GRIN2A GO:0042493| response to drug CREB1;UGT1A1;ABCB1;GRIN2A GO:0007268| synaptic transmission GRIN2A;GRIN2B;OPRM1;OPRD1;OPRK1 GO:0035094| response to nicotine CHRNA7;CREB1 GO:0008542| visual learning GRIN2A;CREB1 GO:0051924| regulation of calcium ion transport OPRD1;GRIN3B 10179:[DB01183 DB00724] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0071260| cellular response to mechanical stimulus TLR4;TLR7;TLR8 GO:0006629| lipid metabolic process CYP3A4 GO:0045087| innate immune response TLR4;TLR7;TLR8 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR8;TLR7;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR7;TLR4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR8;TLR4;TLR7 GO:0051607| defense response to virus OPRK1;TLR8;TLR7 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;TLR8 GO:0050707| regulation of cytokine secretion TLR8;TLR4 GO:0007252| I-kappaB phosphorylation TLR7;TLR4 GO:0006955| immune response OPRD1;TLR4;TLR7;OPRK1 GO:0006954| inflammatory response TLR4;TLR7;TLR8 GO:0002224| toll-like receptor signaling pathway TLR7;TLR4;TLR8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0050729| positive regulation of inflammatory response TLR7;TLR4 GO:0032722| positive regulation of chemokine production TLR7;TLR4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR7;TLR4;CREB1;OPRK1;TLR8 GO:0032755| positive regulation of interleukin-6 production TLR7;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TLR8 GO:0045359| positive regulation of interferon-beta biosynthetic process TLR4;TLR7;TLR8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0032757| positive regulation of interleukin-8 production TLR4;TLR7 GO:0002376| immune system process TLR4;TLR7;TLR8 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 10180:[DB01183 DB06271] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways GO:0007584| response to nutrient SERPINC1;UGT1A1 GO:0044267| cellular protein metabolic process ALB;SERPIND1;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0007595| lactation SERPINC1;CREB1 GO:0043687| post-translational protein modification SERPIND1;SERPINC1;ALB 10181:[DB01183 DB03467] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes ESR1;ABCB1 common pathways GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1B1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB;SLCO2B1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0032355| response to estradiol stimulus ESR1 GO:0002064| epithelial cell development ESR1 GO:0097267| CYP1B1;CYP2C8 GO:0007165| signal transduction OPRK1;ESR2;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0030855| epithelial cell differentiation CES1;AKR1C1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCG2;SLCO2B1;ABCC1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0009636| response to toxin CYP1B1;CES1 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0006811| ion transport SLCO1A2;SLCO2B1 GO:0008285| negative regulation of cell proliferation CYP1B1;OPRM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1A2;AKR1C1 GO:0008584| male gonad development ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:1901529| ABCB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007586| digestion UGT1A1;AKR1C1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0060065| uterus development ESR1;CYP19A1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;AKR1C1;CYP2C8;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0043065| positive regulation of apoptotic process CREB1;CYP1B1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP19A1;CYP2C8;CYP1B1;AKR1C1;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0042493| response to drug UGT1A1;ABCC1;CREB1;ABCB1;ABCG2 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 10182:[DB01183 DB02230] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02230|Immucillin-G PNP common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PNP GO:0006955| immune response OPRD1;OPRK1;PNP;TLR4 10183:[DB01183 DB02911] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02911|2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2C8;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 10184:[DB01183 DB07579] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07579|BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE APCS common genes common pathways GO:0044267| cellular protein metabolic process ALB;APCS GO:0006953| acute-phase response APCS;UGT1A1 GO:0045087| innate immune response TLR4;APCS 10185:[DB01183 DB07756] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways 10186:[DB01183 DB08612] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 10187:[DB01183 DB08347] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08347|4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile ADRB1 common genes common pathways GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRB1;OPRK1 GO:0007165| signal transduction CREB1;TLR4;ADRB1;OPRK1;OPRM1;OPRD1;ESR1 10188:[DB01183 DB07142] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHFR 10189:[DB01183 DB08360] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08360|2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0048511| rhythmic process CREB1;CSNK2A1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;CSNK2A1;OPRD1;ESR1 GO:0006468| protein phosphorylation CREB1;CSNK2A1 10190:[DB01183 DB02888] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02888|FKB-001 FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport FKBP1A;OPRM1 GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A 10191:[DB01183 DB03766] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GPHN;CYP2C8 GO:0050727| regulation of inflammatory response TLR4;ESR1;FABP4 GO:0008152| metabolic process GPHN;UGT1A1;CES1 GO:0050729| positive regulation of inflammatory response FABP4;TLR4 10192:[DB01183 DB01193] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:1904646| TLR4;ADRB2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0007165| signal transduction ADRB2;ESR1;OPRD1;OPRM1;OPRK1;ADRB1;TLR4;CREB1 GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADRB2;ADRB1;OPRK1 GO:0045332| phospholipid translocation ABCB1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 10193:[DB01183 DB03552] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03552|3-Tyrosine TH common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1;TH;OPRM1 GO:0032496| response to lipopolysaccharide TH;OPRM1;TLR4;UGT1A1 GO:0007626| locomotory behavior OPRK1;OPRM1;TH GO:0070848| response to growth factor stimulus TH;OPRM1 GO:0055114| oxidation-reduction process CYP2C8;TH;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;TH GO:0035094| response to nicotine TH;CREB1 GO:0007613| memory CREB1;TH GO:0071363| cellular response to growth factor stimulus CREB1;TH;OPRD1 GO:0032355| response to estradiol stimulus TH;ESR1 GO:0048545| response to steroid hormone stimulus UGT1A1;TH GO:0014070| response to organic cyclic compound UGT1A1;TH GO:0042755| eating behavior OPRK1;TH;OPRD1;OPRM1 GO:0014823| response to activity CREB1;TH GO:0001666| response to hypoxia TH;CREB1 10194:[DB01183 DB02464] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways GO:0007586| digestion PRSS2;UGT1A1;PRSS1 10195:[DB01183 DB08208] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;MAP2K1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;MAP2K1;CREB1 GO:0042981| regulation of apoptotic process ESR1;MAP2K1;CREB1 GO:0000187| activation of MAPK activity TLR4;MAP2K1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;MAP2K1 GO:0008285| negative regulation of cell proliferation OPRM1;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;TLR4 GO:0006468| protein phosphorylation MAP2K1;CREB1 GO:0007165| signal transduction MAP2K1;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 10196:[DB01183 DB02468] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;HMOX1 GO:0042167| heme catabolic process HMOX1;UGT1A1 GO:0043627| response to estrogen stimulus OPRK1;ESR1;HMOX1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity HMOX1;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;HMOX1 GO:0001666| response to hypoxia CREB1;HMOX1 GO:0043065| positive regulation of apoptotic process HMOX1;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HMOX1 GO:0035094| response to nicotine CREB1;HMOX1 GO:0055114| oxidation-reduction process CYP2C8;HMOX1;CYP3A4 10197:[DB01183 DB05766] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0035094| response to nicotine CREB1;DRD2 GO:0008542| visual learning DRD3;CREB1;DRD2 GO:0043278| response to morphine OPRM1;DRD2;OPRK1;DRD3 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0042493| response to drug UGT1A1;DRD3;CREB1;DRD2;ABCB1 GO:0048148| behavioral response to cocaine DRD3;OPRK1;DRD2 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;OPRM1 GO:0007626| locomotory behavior OPRM1;DRD3;OPRK1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;DRD2;CREB1;TLR4;DRD3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0045471| response to ethanol OPRK1;DRD2;DRD3;UGT1A1;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 GO:0042220| response to cocaine OPRM1;DRD3;OPRK1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;DRD2;TLR4 GO:1900273| CREB1;DRD2 GO:0007165| signal transduction DRD3;TLR4;CREB1;OPRK1;DRD2;CHRM1;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;DRD3;CHRM1;OPRD1;OPRM1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 10198:[DB01183 DB00123] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways GO:0002537| nitric oxide production involved in inflammatory response TLR4;SLC7A2 GO:0050727| regulation of inflammatory response ESR1;SLC7A2;TLR4 GO:1900745| KARS;OPRK1 GO:0016032| viral reproduction CREB1;KARS GO:0045893| positive regulation of transcription, DNA-dependent KARS;CREB1;ESR1 GO:0015711| organic anion transport SLC22A4;SLCO1A2 GO:0043032| positive regulation of macrophage activation KARS;TLR4 GO:1900017| KARS;TLR4 GO:0006810| transport SLC7A4;SLC7A1;ABCB1;SLC7A2 GO:0008285| negative regulation of cell proliferation OPRM1;KARS GO:0006811| ion transport SLCO1A2;SLC22A4 GO:0042116| macrophage activation TLR4;SLC7A2 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC22A4;SLC16A10 GO:0070374| positive regulation of ERK1 and ERK2 cascade KARS;TLR4;OPRM1 GO:0000187| activation of MAPK activity KARS;TLR4 10199:[DB01183 DB01812] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01812|Adenosine-3'-5'-Diphosphate HS3ST1;SULT2B1;RNASE2;SULT1A1;HS3ST3A1;RNASE1;SULT2A1;SULT1E1;NDST1;acpS;SULT1B1;topA common genes common pathways GO:0008202| steroid metabolic process SULT2A1;CYP3A4;SULT2B1;CYP2C8;SULT1B1;SULT1A1;SULT1E1;UGT1A1 GO:0045600| positive regulation of fat cell differentiation CREB1;SULT1E1 GO:0008285| negative regulation of cell proliferation OPRM1;SULT2B1 GO:0030855| epithelial cell differentiation SULT1B1;CES1 GO:0008152| metabolic process NDST1;CES1;UGT1A1 GO:0006805| xenobiotic metabolic process SULT1B1;CYP2C8;SULT1A1;CYP3A4;CES1 GO:0050829| defense response to Gram-negative bacterium TLR4;RNASE2 GO:0006629| lipid metabolic process SULT1B1;SULT1A1;CYP3A4;SULT2B1;SULT2A1 GO:0007586| digestion UGT1A1;SULT2A1 GO:0006954| inflammatory response NDST1;TLR4 GO:0008210| estrogen metabolic process SULT1E1;UGT1A1;SULT1A1 GO:0051607| defense response to virus OPRK1;RNASE2;RNASE1 10200:[DB01183 DB00352] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0042493| response to drug ABCC4;ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process ABCC4;CYP3A4;CYP2C8 GO:0002576| platelet degranulation ABCC4;ALB GO:0007626| locomotory behavior OPRM1;OPRK1;HPRT1 GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0055085| transmembrane transport ABCB1;ABCC4;SLCO1A2 GO:0010033| response to organic substance ABCC4;UGT1A1;CREB1 10201:[DB01183 DB00445] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0006338| chromatin remodeling CHD1;ESR1 GO:0006810| transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;UGT2B7;CYP3A4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1;SLCO1A2 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0048511| rhythmic process TOP2A;CREB1 GO:0006351| transcription, DNA-dependent CHD1;ESR1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter CHD1;ESR1 GO:0006629| lipid metabolic process PLA2G4A;UGT2B7;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TOP2A;CREB1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;TOP2A GO:0008152| metabolic process UGT1A1;PLA2G4A;CES1;UGT2B7 GO:0008209| androgen metabolic process CYP3A4;ESR1;UGT2B7 GO:0052695| cellular glucuronidation UGT1A1;UGT2B7 GO:0006355| regulation of transcription, DNA-dependent ESR1;CHD1;CREB1 GO:0042493| response to drug CREB1;ABCC1;UGT1A1;ABCB1 GO:0042752| regulation of circadian rhythm CREB1;TOP2A 10202:[DB01183 DB08519] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08519|N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0016032| viral reproduction CREB1;KDR GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0010629| negative regulation of gene expression CREB1;KDR;OPRD1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;TLR4 GO:0030154| cell differentiation KDR;CREB1 GO:0006468| protein phosphorylation CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR 10203:[DB01183 DB03909] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;INSR;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent INSR;CREB1;ESR1 GO:0000187| activation of MAPK activity TLR4;INSR GO:0030855| epithelial cell differentiation PGK1;CES1 GO:0006811| ion transport ATP2A1;SLCO1A2 GO:0008584| male gonad development ESR1;INSR GO:0006468| protein phosphorylation CREB1;INSR GO:0007613| memory INSR;CREB1 GO:0071456| cellular response to hypoxia PGK1;OPRD1 GO:0071363| cellular response to growth factor stimulus INSR;CREB1;OPRD1 GO:0051659| maintenance of mitochondrion location ALB;ATP2A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;INSR;OPRM1;OPRD1 GO:0070588| calcium ion transmembrane transport OPRM1;ATP2A1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;INSR 10204:[DB01183 DB02152] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02152|K-252a MET;MAP2K1 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MAP2K1;TLR4 GO:0000187| activation of MAPK activity MAP2K1;TLR4 GO:0010628| positive regulation of gene expression TLR4;MAP2K1 GO:0008285| negative regulation of cell proliferation OPRM1;MAP2K1 GO:0006468| protein phosphorylation CREB1;MAP2K1;MET GO:0007165| signal transduction OPRK1;CREB1;TLR4;MAP2K1;ESR1;OPRM1;MET;OPRD1 GO:0010629| negative regulation of gene expression MAP2K1;OPRD1;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;ESR1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;MET GO:0042981| regulation of apoptotic process CREB1;MAP2K1;ESR1 10205:[DB01183 DB03277] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03277|alpha-maltotriose AMY2B common genes common pathways GO:0008152| metabolic process AMY2B;UGT1A1;CES1 GO:0007586| digestion UGT1A1;AMY2B 10206:[DB01183 DB04875] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04875|Pralnacasan CASP1 common genes common pathways GO:0050718| positive regulation of interleukin-1 beta secretion CASP1;TLR4 GO:0009617| response to bacterium CASP1;TLR4 GO:0050727| regulation of inflammatory response ESR1;CASP1;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;CASP1;TLR4 GO:0042981| regulation of apoptotic process ESR1;CREB1;CASP1 GO:0071260| cellular response to mechanical stimulus CASP1;TLR4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CASP1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CASP1 GO:0001666| response to hypoxia CREB1;CASP1 GO:0007165| signal transduction OPRK1;TLR4;CASP1;CREB1;OPRD1;OPRM1;ESR1 10207:[DB01183 DB08205] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport ABCB1;TTR 10208:[DB01183 DB05223] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0043066| negative regulation of apoptotic process HDAC3;HDAC2;HDAC1;ALB GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;HDAC3;ESR1;CREB1;TLR4;HDAC1 GO:0070848| response to growth factor stimulus HDAC6;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC1;HDAC3;HDAC2;ESR1 GO:0032496| response to lipopolysaccharide TLR4;HDAC1;UGT1A1;OPRM1;HDAC2 GO:0007623| circadian rhythm CREB1;HDAC3 GO:0006351| transcription, DNA-dependent HDAC3;HDAC2;ESR1;HDAC6;HDAC1;CREB1 GO:0016032| viral reproduction HDAC1;CREB1 GO:0035094| response to nicotine HDAC2;CREB1 GO:0032760| positive regulation of tumor necrosis factor production HDAC2;HDAC1;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;ESR1;CREB1;HDAC1 GO:0048149| behavioral response to ethanol HDAC2;OPRM1 GO:0006355| regulation of transcription, DNA-dependent HDAC1;CREB1;HDAC3;HDAC2;ESR1;HDAC6 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;HDAC1 GO:0042493| response to drug HDAC2;HDAC1;CREB1;UGT1A1;ABCB1 GO:0032732| positive regulation of interleukin-1 production HDAC1;TLR4;HDAC2 GO:0006338| chromatin remodeling ESR1;HDAC2;HDAC1 GO:0010033| response to organic substance HDAC6;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation HDAC1;OPRM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity HDAC2;ESR1 GO:0048511| rhythmic process HDAC1;CREB1;HDAC2 GO:0009636| response to toxin HDAC6;CES1 GO:0042220| response to cocaine OPRM1;HDAC2;OPRK1 10209:[DB01183 DB03788] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03788|GC-24 THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;CREB1;TLR4;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;THRB GO:0043401| steroid hormone mediated signaling pathway THRB;ESR1 GO:0006351| transcription, DNA-dependent CREB1;THRB;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter THRB;ESR1 GO:0060509| Type I pneumocyte differentiation CREB1;THRB GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;THRB 10210:[DB01183 DB11148] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11148|Butamben CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;BCHE;ORM1;ALB common genes ALB common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CACNA1I;OPRK1;CREB1;TLR4 GO:0070588| calcium ion transmembrane transport CACNA1F;CACNA1A;CACNA1I;CACNA2D3;CACNB1;CACNA1G;CACNA1S;CACNA2D2;CACNB3;CACNA1C;CACNB4;CACNA1D;CACNG1;OPRM1;CACNA1H;CACNA1B;CACNA2D1;CACNB2 GO:0032720| negative regulation of tumor necrosis factor production ORM1;TLR4 GO:0006898| receptor-mediated endocytosis ALB GO:0032715| negative regulation of interleukin-6 production ORM1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0098869| ALB GO:0007204| elevation of cytosolic calcium ion concentration CACNA1A;ESR1;OPRM1;CACNA1C GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport CACNB1;CACNA1I;ABCB1;CACNB3;CACNG1;CACNB4;CACNA1B GO:0051659| maintenance of mitochondrion location ALB GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0032355| response to estradiol stimulus ESR1;KCNJ11 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:1904646| CACNA2D1;CACNB1;CACNA1A;TLR4 GO:0055085| transmembrane transport CACNA1F;CACNA1A;ABCB1;CACNA1I;CACNA1G;CACNA1S;CACNA1C;CACNA1D;SLCO1A2;CACNA1H;CACNA1B;KCNJ11 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0006811| ion transport CACNA2D3;KCNJ1;CACNB1;CACNA1F;CACNA1A;CACNA1I;CACNA2D2;CACNB3;KCNJ15;CACNA1G;CACNA1S;CACNG1;KCNJ10;CACNA1C;CACNB4;CACNA1D;CACNA1B;CACNA2D1;CACNB2;KCNJ11;KCNJ8;SLCO1A2;CACNA1H;KCNJ14;KCNJ12 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0007626| locomotory behavior OPRK1;OPRM1;CACNA1B GO:0002576| platelet degranulation ALB;ORM1 GO:0043066| negative regulation of apoptotic process ALB GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;KCNJ8;OPRM1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0051924| regulation of calcium ion transport CACNA2D1;CACNA1B;OPRD1 GO:0006953| acute-phase response UGT1A1;ORM1 GO:0050718| positive regulation of interleukin-1 beta secretion ORM1;TLR4 GO:0006954| inflammatory response ORM1;TLR4 GO:0043687| post-translational protein modification ALB GO:0051607| defense response to virus KCNJ8;OPRK1 GO:0042493| response to drug BCHE;UGT1A1;CREB1;ABCB1;KCNJ11 GO:0007268| synaptic transmission CACNA1G;CACNB3;CACNB1;OPRK1;OPRM1;OPRD1;CACNB2;CACNA1B;CACNB4 10211:[DB01183 DB02678] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways 10212:[DB01183 DB12698] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0050829| defense response to Gram-negative bacterium TLR4;CD4 GO:0071222| cellular response to lipopolysaccharide OPRK1;CCR5;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD4;TLR4 GO:0006954| inflammatory response CXCR4;CCR5;TLR4 GO:0006955| immune response OPRD1;CD4;OPRK1;TLR4;CCR5 GO:0016032| viral reproduction CD4;CREB1;CCR5;CXCR4 GO:0051924| regulation of calcium ion transport OPRD1;CD4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;CD4;ESR1 GO:0002376| immune system process TLR4;CD4 GO:0007165| signal transduction ESR1;OPRD1;CD4;OPRM1;CXCR4;OPRK1;TLR4;CCR5;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CXCR4;CCR5;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus CD4;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration CXCR4;CCR5;ESR1;OPRM1 GO:0001666| response to hypoxia CXCR4;CREB1 GO:0007411| axon guidance CXCR4;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CD4;OPRM1;TLR4 GO:0000187| activation of MAPK activity CXCR4;TLR4 10213:[DB01183 DB01597] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;CES1 GO:0006811| ion transport SLCO1A2;SLC22A8 GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCB1;SLC22A6 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLCO1A2;SLC22A8 GO:0015711| organic anion transport SLC22A6;SLCO1A2 GO:0043066| negative regulation of apoptotic process DPEP1;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CES1;DPEP1;CYP2C8 10214:[DB01183 DB04048] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PRDX2;CYP2C8 GO:0042981| regulation of apoptotic process CREB1;PRDX2;ESR1 GO:0043066| negative regulation of apoptotic process PRDX2;ALB 10215:[DB01183 DB01709] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways GO:0007568| aging CREB1;ENO3 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;ENO3 10216:[DB01183 DB00031] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0016032| viral reproduction KRT8;CREB1 GO:0043687| post-translational protein modification FGA;ALB GO:0006355| regulation of transcription, DNA-dependent CREB1;CALR;ESR1 GO:0042493| response to drug ABCB1;CREB1;CALR;UGT1A1 GO:0043086| negative regulation of catalytic activity ANXA2;UGT1A1 GO:0042981| regulation of apoptotic process ESR1;CREB1;CALR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CALR GO:0045087| innate immune response TLR4;FGA GO:0006629| lipid metabolic process CYP3A4;LRP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;SERPINE1 GO:0071222| cellular response to lipopolysaccharide SERPINE1;TLR4;OPRK1 GO:0050829| defense response to Gram-negative bacterium TLR4;SERPINE1 GO:0002576| platelet degranulation SERPINE1;PLG;ALB;CLEC3B;FGA GO:0043066| negative regulation of apoptotic process SERPINB2;PLAUR;ALB GO:0071560| cellular response to transforming growth factor beta stimulus CLEC3B;CREB1 GO:0042060| wound healing OPRM1;SERPINB2 GO:0007623| circadian rhythm CREB1;SERPINE1 GO:0010033| response to organic substance UGT1A1;CALR;CREB1 GO:0008285| negative regulation of cell proliferation PLG;OPRM1 GO:0048146| positive regulation of fibroblast proliferation ESR1;ANXA2 GO:0010628| positive regulation of gene expression CALR;TLR4 GO:1904646| LRP1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGA;TLR4;OPRM1 GO:0044267| cellular protein metabolic process PLG;FGA;ALB GO:0007165| signal transduction OPRM1;OPRD1;ESR1;FGA;PLAUR;OPRK1;CREB1;TLR4 GO:0002376| immune system process TLR4;FGA GO:0006898| receptor-mediated endocytosis ALB;CALR;LRP1 GO:0032757| positive regulation of interleukin-8 production SERPINE1;TLR4 GO:0002224| toll-like receptor signaling pathway TLR4;FGA GO:0007568| aging CANX;LRP1;CREB1 GO:0050821| protein stabilization CREB1;CALR GO:0032355| response to estradiol stimulus CALR;ESR1 GO:0050729| positive regulation of inflammatory response TLR4;SERPINE1 10217:[DB01183 DB00095] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00095|Efalizumab ITGAL;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0009617| response to bacterium FCGR2B;TLR4 GO:0006954| inflammatory response ITGAL;TLR4;FCGR2B GO:0006955| immune response OPRK1;FCGR1A;C1R;FCGR2B;FCGR3B;TLR4;FCGR3A;OPRD1;FCGR2C;C1QC GO:0016032| viral reproduction CREB1;FCGR2B GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0045087| innate immune response FCGR1A;TLR4;C1R;C1QB;C1QA;C1QC GO:1904646| FCGR2B;TLR4 GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB GO:0002376| immune system process C1QA;C1QC;FCGR1A;FCGR2A;TLR4;C1R;C1QB GO:0007165| signal transduction ITGAL;ESR1;OPRD1;FCGR2C;OPRM1;TLR4;FCGR2B;CREB1;OPRK1;FCGR1A 10218:[DB01183 DB09526] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09526|Hydroquinone TYR;ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0008152| metabolic process CES1;TYR;UGT1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;TYR;CYP2C8 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0051659| maintenance of mitochondrion location ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB 10219:[DB01183 DB07456] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways GO:0006468| protein phosphorylation CREB1;PDPK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PDPK1;CREB1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;PDPK1 10220:[DB01183 DB08467] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;CRABP2 GO:0042573| retinoic acid metabolic process CRABP2;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent CRABP2;ESR1;CREB1 10221:[DB01183 DB04389] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04389|Ado-P-Ch2-P-Ps-Ado FHIT common genes common pathways GO:0006351| transcription, DNA-dependent FHIT;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;FHIT;ESR1 10222:[DB01183 DB08654] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08654|TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 10223:[DB01183 DB01207] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0007584| response to nutrient TBXA2R;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;TBXA2R GO:0007204| elevation of cytosolic calcium ion concentration TBXA2R;OPRM1;ESR1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;TBXA2R;CREB1;TLR4;OPRK1 GO:0042493| response to drug TBXA2R;CREB1;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;TBXAS1 GO:0006954| inflammatory response TLR4;TBXA2R GO:0032496| response to lipopolysaccharide OPRM1;TBXA2R;UGT1A1;TLR4 GO:0045471| response to ethanol OPRM1;TBXA2R;UGT1A1;OPRK1 GO:0071222| cellular response to lipopolysaccharide TBXA2R;TLR4;OPRK1 GO:0006629| lipid metabolic process CYP3A4;TBXAS1 10224:[DB01183 DB00043] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;MS4A2;OPRD1;OPRM1 GO:0006954| inflammatory response MS4A2;TLR4 GO:0006955| immune response MS4A2;OPRD1;TLR4;OPRK1 10225:[DB01183 DB01194] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0045471| response to ethanol CA3;OPRM1;OPRK1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0045672| positive regulation of osteoclast differentiation CA2;CREB1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010033| response to organic substance CA2;CREB1;UGT1A1 GO:0043627| response to estrogen stimulus CA2;OPRK1;ESR1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 10226:[DB01183 DB09343] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0006811| ion transport SLC22A2;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;SLC47A1;SLC22A2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC47A1 GO:0030154| cell differentiation CREB1;TYMP GO:0015711| organic anion transport SLC22A2;SLCO1A2 GO:0008152| metabolic process CES1;TYMP;UGT1A1 10227:[DB01183 DB08608] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08608|4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE PDK2 common genes common pathways GO:0006468| protein phosphorylation PDK2;CREB1 10228:[DB01183 DB00974] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0007568| aging CREB1;ADA GO:0009636| response to toxin CES1;PON3 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0001666| response to hypoxia CREB1;ADA GO:0030890| positive regulation of B cell proliferation TLR4;ADA GO:0001889| liver development ADA;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0060065| uterus development CYP19A1;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;ADA GO:0043278| response to morphine OPRK1;ADA;OPRM1 10229:[DB01183 DB00240] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NR3C1;ESR1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;CREB1;TLR4 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;NR3C1;OPRD1;ESR1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 10230:[DB01183 DB05282] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05282|MCC AIFM1 common genes common pathways GO:0055114| oxidation-reduction process AIFM1;CYP3A4;CYP2C8 GO:0043065| positive regulation of apoptotic process CREB1;AIFM1 GO:0009636| response to toxin CES1;AIFM1 GO:1902065| AIFM1;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;AIFM1;UGT1A1 10231:[DB01183 DB00954] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00954|Dirithromycin CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 10232:[DB01183 DB05249] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05249|FavId CSF3R common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4;CSF3R 10233:[DB01183 DB08448] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 10234:[DB01183 DB03690] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PITPNA GO:0007409| axonogenesis CREB1;PITPNA 10235:[DB01183 DB02850] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;HPD 10236:[DB01183 DB03608] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03608|Diminazene PRDX5;PRSS1;AOC1 common genes common pathways GO:0098869| PRDX5;ALB GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;AOC1 GO:0043066| negative regulation of apoptotic process ALB;PRDX5 GO:0007586| digestion PRSS1;UGT1A1 GO:0042493| response to drug ABCB1;AOC1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process AOC1;CYP2C8;CYP3A4;PRDX5 GO:0006954| inflammatory response TLR4;PRDX5 10237:[DB01183 DB06600] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 10238:[DB01183 DB06497] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06497|Aplaviroc CCR5 common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;CCR5;TLR4;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CCR5;OPRK1;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration CCR5;OPRM1;ESR1 GO:0006954| inflammatory response CCR5;TLR4 GO:0006955| immune response OPRD1;TLR4;CCR5;OPRK1 GO:0016032| viral reproduction CCR5;CREB1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;CCR5 10239:[DB01183 DB08707] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08707|4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;ALB GO:0006468| protein phosphorylation CREB1;PIM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 10240:[DB01183 DB07717] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;AR;OPRD1;OPRM1;ESR1 GO:0006810| transport AR;ABCB1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0016579| protein deubiquitination ESR1;AR GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression TLR4;AR 10241:[DB01183 DB00846] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0002933| CYP3A4;CYP2C8 GO:0007165| signal transduction OPRM1;NR3C1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR3C1;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1;TLR4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 10242:[DB01183 DB04585] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04585|DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID ARG1 common genes common pathways GO:0042493| response to drug ABCB1;CREB1;UGT1A1;ARG1 GO:0001889| liver development UGT1A1;ARG1 GO:0032496| response to lipopolysaccharide OPRM1;ARG1;TLR4;UGT1A1 GO:0045087| innate immune response ARG1;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;CREB1 GO:0007568| aging CREB1;ARG1 GO:0048545| response to steroid hormone stimulus ARG1;UGT1A1 GO:0002376| immune system process ARG1;TLR4 10243:[DB01183 DB01125] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01125|Anisindione GGCX common genes common pathways 10244:[DB01183 DB02205] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02205|6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GAPDHS;CYP2C8 10245:[DB01183 DB01606] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLCO1A2;SLC22A6;ABCB1 GO:0006811| ion transport SLCO1A2;SLC22A8 GO:0009636| response to toxin CES1;SLC22A8 GO:0015711| organic anion transport SLC22A6;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1A2;SLC22A8 10246:[DB01183 DB03191] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03191|3-Oxiran-2ylalanine MAT1A common genes common pathways 10247:[DB01183 DB06909] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PDE4B;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction OPRK1;PDE4B;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0032729| positive regulation of interferon-gamma production PDE4B;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PDE4B 10248:[DB01183 DB12095] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;TPH2 GO:0043627| response to estrogen stimulus TPH2;OPRK1;ESR1 GO:0014823| response to activity TPH2;CREB1 GO:0045600| positive regulation of fat cell differentiation CREB1;TPH1 GO:0007623| circadian rhythm TPH2;TPH1;CREB1 GO:0060749| mammary gland alveolus development ESR1;TPH1 GO:0055114| oxidation-reduction process CYP3A4;TPH1;TPH2;CYP2C8 10249:[DB01183 DB08806] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08806|Roxatidine acetate HRH2 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;HRH2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;HRH2 GO:0007613| memory CREB1;HRH2 GO:0007165| signal transduction ESR1;HRH2;OPRM1;OPRD1;CREB1;TLR4;OPRK1 GO:0006955| immune response HRH2;OPRD1;OPRK1;TLR4 GO:0008542| visual learning CREB1;HRH2 10250:[DB01183 DB12498] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0006954| inflammatory response CXCR4;TLR4 GO:0016032| viral reproduction CXCR4;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CXCR4;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;CXCR4 GO:0007165| signal transduction CREB1;TLR4;CXCR4;OPRK1;ESR1;OPRM1;OPRD1 GO:0000187| activation of MAPK activity TLR4;CXCR4 GO:0001666| response to hypoxia CXCR4;CREB1 GO:0007411| axon guidance CXCR4;CREB1 10251:[DB01183 DB07388] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07388|ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2;NOS3 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;NOS2;OPRK1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;NOS2;TLR4 GO:0009617| response to bacterium TLR4;NOS2 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP2C8;NOS3;NOS2;CYP3A4 GO:0010629| negative regulation of gene expression CREB1;NOS2;ESR1;OPRD1 GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 GO:0001666| response to hypoxia NOS2;CREB1 10252:[DB01183 DB00827] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLCO1A2 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0015711| organic anion transport SLCO1A2;SLC22A6 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB;SLC22A6 10253:[DB01183 DB11967] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes UGT1A1 common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;IL1B;IL6;TNF GO:0006955| immune response TNF;TLR4;IL6;OPRK1;IL1B;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF;IL6;IL1B GO:0006954| inflammatory response IL1B;IL6;TLR4;TNF GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006953| acute-phase response UGT1A1;IL6 GO:0008210| estrogen metabolic process UGT1A1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;IL6;CREB1;TNF;MAP2K2;ESR1 GO:0010629| negative regulation of gene expression CREB1;TNF;OPRD1;ESR1;MAP2K2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0051607| defense response to virus OPRK1;IL6 GO:0052695| cellular glucuronidation UGT1A1 GO:0043687| post-translational protein modification ALB;IL6 GO:0043491| protein kinase B signaling cascade IL1B;TNF;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A4;CYP1A2 GO:0042742| defense response to bacterium TNF;TLR4 GO:0006789| bilirubin conjugation UGT1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8;CYP2C19 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4;IL1B GO:0008152| metabolic process CES1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CES1;CYP3A4;CYP1A2 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR4;MAP3K1 GO:0043066| negative regulation of apoptotic process ALB;IL6 GO:0031663| lipopolysaccharide-mediated signaling pathway IL1B;TLR4;TNF GO:0050727| regulation of inflammatory response ESR1;TNF;TLR4 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0043065| positive regulation of apoptotic process IL6;TNF;CREB1 GO:0050829| defense response to Gram-negative bacterium IL6;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;IL6;TNF;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IL6;IL1B;TLR4;TNF;CREB1 GO:1900745| OPRK1;IL1B GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0042594| response to starvation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0071260| cellular response to mechanical stimulus TLR4;IL1B;MAP3K1 GO:0007586| digestion UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TNF GO:0042981| regulation of apoptotic process CREB1;MAP2K2;MAP3K1;ESR1 GO:0032729| positive regulation of interferon-gamma production TNF;TLR4;IL1B GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C19 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;IL1B;UGT1A1;TLR4 GO:0051552| flavone metabolic process UGT1A1 GO:0046330| positive regulation of JNK cascade IL1B;TLR4;TNF GO:0001889| liver development UGT1A1 GO:0097190| apoptotic signaling pathway TNF;TLR4 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:1904224| UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;TLR4;TNF GO:0010628| positive regulation of gene expression TNF;TLR4;IL1B;IL6 GO:0010033| response to organic substance TNF;CREB1;UGT1A1;CYP1A2 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;IL1B;IL6 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0000187| activation of MAPK activity IL1B;TNF;TLR4;MAP2K2 GO:0044267| cellular protein metabolic process ALB;IL6 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;MAP2K2;OPRM1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;IL1B;TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production IL1B;IL6;TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0032757| positive regulation of interleukin-8 production TNF;TLR4;IL1B GO:0031100| organ regeneration UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0032722| positive regulation of chemokine production TNF;TLR4;IL6 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP2C19;CYP1A2 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;IL6;OPRD1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;IL1B;ESR1;OPRM1;OPRD1 GO:0042167| heme catabolic process UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8;CYP2C19 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0051384| response to glucocorticoid stimulus IL6;UGT1A1;TNF GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0006468| protein phosphorylation MAP2K2;MAP3K1;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 10254:[DB01183 DB00629] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ADRA2A;ADRA2B;ESR1;OPRD1;OPRM1 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1;ADRA2B GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A 10255:[DB01183 DB01632] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0007595| lactation CREB1;APRT GO:0016032| viral reproduction UCKL1;CREB1 GO:0007626| locomotory behavior OPRM1;OPRK1;HPRT1 GO:0008152| metabolic process UGT1A1;UCKL1;CES1 10256:[DB01183 DB02821] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02821|Canaline OAT common genes common pathways 10257:[DB01183 DB01370] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes ALB common pathways GO:0002576| platelet degranulation TF;APP;ALB GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0043065| positive regulation of apoptotic process APP;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;APP;TLR4;CREB1 GO:0007626| locomotory behavior OPRM1;APP;OPRK1 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0042346| positive regulation of NF-kappaB import into nucleus APP;TLR4 GO:0043066| negative regulation of apoptotic process ALB GO:1990090| APP;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;ESR1 GO:0045087| innate immune response APP;TLR4 GO:0071260| cellular response to mechanical stimulus TLR4;ATP1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046330| positive regulation of JNK cascade APP;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;APP GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;APP GO:0008542| visual learning APP;CREB1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;APP GO:0042493| response to drug ATP1A1;UGT1A1;CREB1;ABCB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;APP GO:1901215| CREB1;APP GO:0043687| post-translational protein modification ALB;APP;TF GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;APP GO:1900273| APP;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;APP GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;APP;OPRM1;OPRD1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0006468| protein phosphorylation CREB1;APP GO:0007613| memory CREB1;APP GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;APP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;APP;OPRM1;OPRD1 GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0010628| positive regulation of gene expression APP;TLR4 GO:1904646| TLR4;APP GO:1903223| APP;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;APP GO:0006811| ion transport ATP1A1;TF;SLCO1A2 GO:0007409| axonogenesis APP;CREB1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;APP;TLR4 GO:0000187| activation of MAPK activity APP;TLR4 GO:0001895| retina homeostasis ALB;TF GO:0008344| adult locomotory behavior APP;OPRD1 GO:0044267| cellular protein metabolic process ALB;APP;TF 10258:[DB01183 DB04818] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04818|Iproniazid MAOB;CYP2D6;CYP2C9 common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;MAOB;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6;MAOB;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0032496| response to lipopolysaccharide TLR4;MAOB;UGT1A1;OPRM1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0045471| response to ethanol OPRM1;OPRK1;MAOB;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP2C9;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0009636| response to toxin MAOB;CES1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP2C9;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C9;UGT1A1;CYP3A4 10259:[DB01183 DB02207] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02207|7-Nitroindazole NOS3;NOS2 common genes common pathways GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;NOS2 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;NOS2 GO:0007623| circadian rhythm NOS2;CREB1 GO:0010629| negative regulation of gene expression CREB1;NOS2;OPRD1;ESR1 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP3A4;NOS2;CYP2C8;NOS3 GO:0009617| response to bacterium TLR4;NOS2 GO:0001666| response to hypoxia NOS2;CREB1 GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 10260:[DB01183 DB11294] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11294|Coccidioides immitis spherule HLA-A;HLA-A;HLA-B common genes common pathways GO:0002376| immune system process HLA-B;HLA-A;TLR4 GO:0016032| viral reproduction HLA-B;HLA-A;CREB1 GO:0006955| immune response OPRD1;HLA-B;OPRK1;HLA-A;TLR4 GO:0045087| innate immune response HLA-B;TLR4 10261:[DB01183 DB08800] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08800|Chloropyramine HRH1 common genes common pathways GO:0007165| signal transduction ESR1;HRH1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0007613| memory HRH1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HRH1;OPRD1;OPRK1 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;ESR1;OPRK1 10262:[DB01183 DB07239] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 10263:[DB01183 DB08384] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways GO:0008152| metabolic process CES1;PDE10A;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;PDE10A GO:0007165| signal transduction OPRK1;CREB1;TLR4;PDE10A;OPRM1;OPRD1;ESR1 10264:[DB01183 DB05398] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05398|C31G CD9 common genes common pathways GO:0002576| platelet degranulation ALB;CD9 GO:0008285| negative regulation of cell proliferation OPRM1;CD9 10265:[DB01183 DB00054] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:1904646| TLR4;FCGR2B GO:0007165| signal transduction CREB1;FCGR2B;TLR4;OPRK1;FCGR1A;ESR1;OPRM1;OPRD1;FCGR2C GO:0006898| receptor-mediated endocytosis ALB;FCGR1A;FCGR2B;VTN GO:0002376| immune system process C1R;C1QB;TLR4;FCGR1A;FCGR2A;C1S;C1QC;C1QA GO:0009617| response to bacterium TLR4;FCGR2B GO:0006954| inflammatory response FCGR2B;TLR4 GO:0016032| viral reproduction ITGB3;CREB1;FCGR2B GO:0006955| immune response FCGR1A;OPRK1;C1R;FCGR3B;FCGR2B;TLR4;VTN;FCGR2C;OPRD1;FCGR3A;C1QC GO:0046330| positive regulation of JNK cascade TLR4;FCGR2B GO:0042060| wound healing ITGB3;OPRM1 GO:0045087| innate immune response TLR4;C1QB;C1R;FCGR1A;C1S;C1QC;C1QA GO:0002576| platelet degranulation ALB;ITGB3;ITGA2B 10266:[DB01183 DB01277] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0044267| cellular protein metabolic process ALB;IGFBP3 GO:0000187| activation of MAPK activity INSR;TLR4 GO:1904646| IGF1R;TLR4 GO:0008584| male gonad development ESR1;INSR GO:0008285| negative regulation of cell proliferation IGFBP3;OPRM1 GO:0071363| cellular response to growth factor stimulus CREB1;INSR;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;IGF2R;INSR;OPRM1;OPRD1 GO:0007613| memory CREB1;INSR GO:0006468| protein phosphorylation CREB1;INSR;IGFBP3;IGF1R GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;INSR;TLR4 GO:0006898| receptor-mediated endocytosis ALB;IGF2R GO:0031100| organ regeneration UGT1A1;IGF2R GO:0007165| signal transduction ESR1;OPRM1;IGF1R;OPRD1;CREB1;TLR4;IGF2R;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent INSR;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent INSR;CREB1;ESR1 GO:0043687| post-translational protein modification ALB;IGFBP3 GO:0006955| immune response TLR4;OPRK1;IGF1R;OPRD1 GO:0001889| liver development IGF2R;UGT1A1 GO:0043066| negative regulation of apoptotic process IGF1R;ALB GO:0043065| positive regulation of apoptotic process IGF2R;CREB1;IGFBP3 GO:0042981| regulation of apoptotic process ESR1;IGFBP3;IGF2R;CREB1 10267:[DB01183 DB02746] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes ESR1 common pathways GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0030879| mammary gland development PGR;CREB1 GO:0006811| ion transport SLCO1A2;SLCO2B1 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLCO2B1 GO:0001666| response to hypoxia PPARA;CREB1 GO:0010628| positive regulation of gene expression PPARD;TLR4 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;SLCO2B1;RXRA GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1;PPARD GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance UGT1A1;CREB1;PPARG;PPARD GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0014823| response to activity PPARD;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0048511| rhythmic process PPARA;PPARG;CREB1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1A2 GO:0032355| response to estradiol stimulus ESR1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRM1;OPRD1 GO:0071392| cellular response to estradiol stimulus ESR2;UGT1A1;ESR1 GO:0030154| cell differentiation PPARD;CREB1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0071456| cellular response to hypoxia PPARD;OPRD1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction PGR;OPRK1;ESR2;TLR4;PPARG;CREB1;OPRD1;OPRM1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;RXRA;CREB1;PPARG;ESR1;PPARA;PPARD GO:0010629| negative regulation of gene expression PGR;CREB1;ESR1;OPRD1 GO:0042493| response to drug UGT1A1;CREB1;PPARG;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;ESR1;PGR;RXRG;ESR2;RXRA;RXRB;CREB1;PPARG GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:1901215| PPARA;CREB1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0016032| viral reproduction RXRA;CREB1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0048863| stem cell differentiation ESR1 GO:0042752| regulation of circadian rhythm CREB1;PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRB;RXRA;PGR;ESR2;RXRG;PPARD;ESR1;PPARA GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;ESR1;RXRA;PPARG GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0042060| wound healing OPRM1;PPARD;PPARA GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway RXRA;RXRB;PPARG;RXRG;ESR2;PGR;PPARA;ESR1;PPARD GO:0006351| transcription, DNA-dependent PGR;ESR2;RXRG;RXRA;RXRB;CREB1;PPARG;PPARD;ESR1;PPARA GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0060065| uterus development ESR1 GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PPARD GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;RXRG;ESR2;RXRA;TLR4;RXRB;CREB1;PPARG;PPARA;ESR1 GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4;PPARD GO:0042594| response to starvation PPARG;UGT1A1 GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;PPARG;RXRA;PPARA;ESR1;PPARD GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0042981| regulation of apoptotic process ESR1;CREB1 10268:[DB01183 DB02175] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02175|Malonic acid panD;SRC;SNRPA common genes common pathways GO:0016032| viral reproduction CREB1;SRC GO:0042493| response to drug SRC;UGT1A1;CREB1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;SRC;ESR1 GO:0045087| innate immune response SRC;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;SRC GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0043065| positive regulation of apoptotic process SRC;CREB1 GO:0060065| uterus development ESR1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;SRC GO:0071398| cellular response to fatty acid CREB1;SRC GO:0007411| axon guidance CREB1;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0010628| positive regulation of gene expression SRC;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;SRC GO:0007165| signal transduction ESR1;OPRM1;OPRD1;SRC;CREB1;TLR4;OPRK1 GO:0002376| immune system process TLR4;SRC GO:0071456| cellular response to hypoxia SRC;OPRD1 GO:0006468| protein phosphorylation CREB1;SRC GO:0036120| CREB1;SRC 10269:[DB01183 DB00892] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways GO:0007600| sensory perception OPRM1;OPRK1;SCN10A GO:0042493| response to drug ABCB1;BCHE;UGT1A1;CREB1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1;SCN10A GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient BCHE;UGT1A1 GO:0055085| transmembrane transport SCN10A;ABCB1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SCN10A GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE 10270:[DB01183 DB02558] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways GO:0019233| sensory perception of pain OPRK1;OPRM1;MME;OPRD1 10271:[DB01183 DB08530] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 10272:[DB01183 DB13925] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways GO:0042594| response to starvation SSTR2;UGT1A1 GO:0007586| digestion UGT1A1;SSTR2 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;SSTR2;OPRK1 GO:0071385| cellular response to glucocorticoid stimulus SSTR2;UGT1A1 GO:0071392| cellular response to estradiol stimulus SSTR2;UGT1A1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;SSTR2;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;SSTR2 GO:0007165| signal transduction OPRK1;TLR4;CREB1;SSTR2;ESR1;OPRD1;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;SSTR2 GO:0007584| response to nutrient SSTR2;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;SSTR2 10273:[DB01183 DB01180] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01180|Rescinnamine ACE common genes common pathways 10274:[DB01183 DB02170] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02170|1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One CSNK2A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0006351| transcription, DNA-dependent ESR1;CSNK2A1;CREB1 GO:0048511| rhythmic process CSNK2A1;CREB1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;CSNK2A1;OPRM1;ESR1 10275:[DB01183 DB02512] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways GO:0002576| platelet degranulation ALB;ALDOA 10276:[DB01183 DB12589] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12589|Dacetuzumab CD40 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;CD40 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;CD40 GO:0097190| apoptotic signaling pathway CD40;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;CD40;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CD40;CREB1 GO:0071260| cellular response to mechanical stimulus CD40;TLR4 GO:0051607| defense response to virus OPRK1;CD40 GO:0043491| protein kinase B signaling cascade CD40;CREB1 GO:0009617| response to bacterium TLR4;CD40 GO:0006955| immune response CD40;TLR4;OPRK1;OPRD1 GO:0006954| inflammatory response CD40;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CD40 GO:0032735| positive regulation of interleukin-12 production CD40;TLR4 GO:0002376| immune system process CD40;TLR4 GO:0030890| positive regulation of B cell proliferation TLR4;CD40 10277:[DB01183 DB07106] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways 10278:[DB01183 DB09097] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug UGT1A1;CREB1;DRD2;ABCB1;DRD1 GO:0007268| synaptic transmission DRD5;OPRD1;OPRM1;OPRK1 GO:0035094| response to nicotine CREB1;DRD2 GO:0008542| visual learning DRD1;CREB1;DRD2 GO:0043278| response to morphine OPRM1;DRD2;OPRK1 GO:0042711| maternal behavior OPRK1;DRD1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRK1;DRD2;UGT1A1;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0042060| wound healing DRD5;OPRM1 GO:0048148| behavioral response to cocaine OPRK1;DRD2;DRD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD5;DRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;DRD2;ESR1 GO:0007626| locomotory behavior DRD1;OPRM1;DRD2;OPRK1 GO:0042220| response to cocaine DRD5;DRD1;OPRM1;DRD2;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0009636| response to toxin CES1;DRD2 GO:0007409| axonogenesis CREB1;DRD2 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;DRD1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0010628| positive regulation of gene expression DRD1;TLR4 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007613| memory CREB1;DRD1 GO:0007186| G-protein coupled receptor signaling pathway DRD5;DRD1;OPRM1;OPRD1;DRD2;OPRK1 GO:0014002| astrocyte development TLR4;DRD1 GO:0007165| signal transduction TLR4;CREB1;DRD2;OPRK1;OPRD1;OPRM1;ESR1;DRD5;DRD1 GO:1900273| CREB1;DRD2 10279:[DB01183 DB08629] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08629|N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 GO:0006811| ion transport ATP5B;SLCO1A2 10280:[DB01183 DB04886] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04886|Calanolide A CYP3A4 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 10281:[DB01183 DB05075] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0016032| viral reproduction CREB1;KDR GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;KDR GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0043066| negative regulation of apoptotic process FLT4;KDR;ALB GO:0045087| innate immune response TLR4;CSK GO:0046330| positive regulation of JNK cascade FLT4;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;CSK GO:0070373| negative regulation of ERK1 and ERK2 cascade CSK;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade KDR;TLR4;FLT4;OPRM1 GO:0002376| immune system process TLR4;CSK GO:0010863| positive regulation of phospholipase C activity FLT1;ESR1 GO:0032715| negative regulation of interleukin-6 production TLR4;CSK GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0006468| protein phosphorylation KDR;CSK;CREB1;FLT4;FLT1 GO:0030154| cell differentiation KDR;CSK;CREB1;FLT1 10282:[DB01183 DB04736] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways GO:0045087| innate immune response PGLYRP3;TLR4 GO:0042742| defense response to bacterium TLR4;PGLYRP3 GO:0002376| immune system process TLR4;PGLYRP3 GO:0032689| negative regulation of interferon-gamma production TLR4;PGLYRP3 10283:[DB01183 DB05364] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05364|ROX-888 CCL3 common genes common pathways GO:0010628| positive regulation of gene expression TLR4;CCL3 GO:0045671| negative regulation of osteoclast differentiation TLR4;CCL3 GO:0070374| positive regulation of ERK1 and ERK2 cascade CCL3;OPRM1;TLR4 GO:0009636| response to toxin CCL3;CES1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1;CCL3 GO:0007610| behavior OPRK1;CCL3 GO:0050729| positive regulation of inflammatory response TLR4;CCL3 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;CCL3 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;CCL3 GO:0032760| positive regulation of tumor necrosis factor production CCL3;TLR4 GO:0006955| immune response CCL3;OPRD1;OPRK1;TLR4 GO:0006954| inflammatory response TLR4;CCL3 GO:0043491| protein kinase B signaling cascade CREB1;CCL3 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1;CCL3 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;CCL3 10284:[DB01183 DB00278] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00278|Argatroban F2;CYP3A4;CYP3A5 common genes CYP3A4 common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;F2;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP3A5;CYP2C8 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0002933| CYP3A4;CYP2C8;CYP3A5 GO:0036378| CYP3A4 GO:0044267| cellular protein metabolic process F2;ALB GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP3A5 GO:0006953| acute-phase response UGT1A1;F2 10285:[DB01183 DB00067] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;ABCC2;UGT1A1;TLR4 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ABCC2 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCC2 GO:0042711| maternal behavior OPRK1;AVPR1A GO:0032609| interferon-gamma production AVPR2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration AVPR1B;OPRM1;ESR1;AVPR1A GO:0006810| transport ABCC2;ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;AVPR1A;AVPR1B;AVPR2;OPRK1 GO:0007165| signal transduction ESR1;AVPR1A;OPRD1;OPRM1;TLR4;CREB1;AVPR1B;OPRK1;AVPR2 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0032870| cellular response to hormone stimulus UGT1A1;AVPR1B;ABCC2;AVPR2;AVPR1A GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;AVPR2 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCC2;ABCB1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;ABCC2 GO:0010033| response to organic substance AVPR1A;UGT1A1;CREB1 GO:0010628| positive regulation of gene expression TLR4;AVPR2 10286:[DB01183 DB03216] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03216|(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine AHCY common genes common pathways GO:0001666| response to hypoxia CREB1;AHCY GO:0007584| response to nutrient AHCY;UGT1A1 10287:[DB01183 DB00983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2A6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP2C9;CYP2C19;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9;CYP2A6 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;CYP2C19 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRD1;OPRM1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:1904646| ADRB2;TLR4 GO:0042755| eating behavior ADRB3;OPRK1;OPRM1;OPRD1 GO:0097267| CYP2C9;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP2C9;UGT1A1;CYP2D6;CYP2C19;CYP2C8 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;ADRB2;ADRB1;OPRK1;ADRB3;CREB1;TLR4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8;CYP2D6 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0007568| aging ADRB3;CREB1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;ADRB3;OPRK1;ADRB1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2C8;CYP2C19;CYP2D6;UGT1A1;CYP2C9 10288:[DB01183 DB05204] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05204|XL418 BTK common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity BTK;TLR4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;BTK GO:0002755| MyD88-dependent toll-like receptor signaling pathway BTK;TLR4 GO:0045087| innate immune response TLR4;BTK GO:0097190| apoptotic signaling pathway BTK;TLR4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;BTK GO:0010033| response to organic substance BTK;CREB1;UGT1A1 GO:0002376| immune system process TLR4;BTK GO:0007249| I-kappaB kinase/NF-kappaB cascade BTK;TLR4 GO:0006468| protein phosphorylation BTK;CREB1 10289:[DB01183 DB02902] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;SULT1E1;UGT1A1;CYP3A4 GO:0045600| positive regulation of fat cell differentiation CREB1;SULT1E1 GO:0008210| estrogen metabolic process SULT1E1;UGT1A1 10290:[DB01183 DB07116] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07116|1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE UNG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;UNG GO:0016032| viral reproduction UNG;CREB1 10291:[DB01183 DB07646] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0042594| response to starvation DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0007595| lactation CREB1;DHODH GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHODH GO:0042493| response to drug DHODH;ABCB1;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;DHODH 10292:[DB01183 DB04599] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway DRD2;OPRK1;OPRM1;OPRD1;HTR2A GO:0006810| transport ABCB1;GRIA3 GO:0007568| aging HTR2A;CREB1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory HTR2A;CREB1 GO:1900273| DRD2;CREB1 GO:0007610| behavior HTR2A;OPRK1 GO:0007165| signal transduction GRIA2;ESR1;HTR2A;OPRM1;OPRD1;OPRK1;DRD2;CREB1;TLR4 GO:0009636| response to toxin DRD2;CES1 GO:0006811| ion transport GRIA2;GRIA3;SLCO1A2 GO:0007409| axonogenesis DRD2;CREB1 GO:0042220| response to cocaine OPRM1;DRD2;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;DRD2;HTR2A;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0019233| sensory perception of pain OPRK1;HTR2A;OPRM1;OPRD1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIA2;OPRM1;GRIA3;DRD2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;HTR2A;OPRM1;OPRD1 GO:0045471| response to ethanol UGT1A1;DRD2;OPRK1;OPRM1 GO:0048148| behavioral response to cocaine HTR2A;DRD2;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;CREB1;TLR4;ESR1 GO:0007626| locomotory behavior OPRM1;DRD2;OPRK1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug HTR2A;UGT1A1;CREB1;ABCB1;DRD2 GO:0007268| synaptic transmission OPRK1;GRIA2;HTR2A;OPRD1;OPRM1 GO:0016032| viral reproduction CREB1;HTR2A GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning CREB1;DRD2 GO:0043278| response to morphine OPRK1;DRD2;OPRM1 10293:[DB01183 DB01667] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CREB1;PNP;UGT1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0006955| immune response PNP;TLR4;OPRK1;OPRD1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CES1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 10294:[DB01183 DB06831] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06831|2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE PIK3CG;PIK3CD common genes common pathways GO:0010628| positive regulation of gene expression TLR4;PIK3CD GO:0007411| axon guidance CREB1;PIK3CD GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;PIK3CG GO:0006468| protein phosphorylation PIK3CD;CREB1;PIK3CG GO:0030154| cell differentiation CREB1;PIK3CD GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;PIK3CG GO:0002376| immune system process PIK3CG;TLR4;PIK3CD GO:0007165| signal transduction CREB1;TLR4;PIK3CD;OPRK1;ESR1;OPRM1;OPRD1 GO:0006954| inflammatory response PIK3CD;PIK3CG;TLR4 GO:0045087| innate immune response PIK3CG;TLR4;PIK3CD 10295:[DB01183 DB00935] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ADRA1A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;OPRD1;OPRM1;ESR1;ADRA1A;OPRK1;ADRA1D GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1;ADRA2C GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;ADRA1A;ADRA2A;OPRK1;OPRM1;OPRD1;ADRA2C;ADRA2B;ADRA1B GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1D;ADRA1B;OPRM1;ESR1 GO:0007568| aging ADRA1A;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A;OPRK1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0007165| signal transduction OPRK1;ADRA2A;ADRA1A;TLR4;CREB1;ADRA1D;ADRA1B;ADRA2B;ESR1;ADRA2C;OPRD1;OPRM1 10296:[DB01183 DB05016] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLCO1B3;SLC22A8;SLCO1A2 GO:0015711| organic anion transport SLC22A6;SLCO1A2;SLCO1B3 GO:0006811| ion transport SLCO1B3;SLC22A8;SLCO1A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;SLCO1B3;SLC22A6;ABCB1 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B3;ALB 10297:[DB01183 DB01341] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways GO:0006811| ion transport SLCO1A2;GABRA1 GO:0006810| transport GABRA1;ABCB1 10298:[DB01183 DB02183] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways GO:0007165| signal transduction HINT1;ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0006351| transcription, DNA-dependent ESR1;HINT1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HINT1;ESR1 10299:[DB01183 DB00129] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways GO:0032868| response to insulin stimulus OTC;OPRK1 GO:0042116| macrophage activation SLC7A2;TLR4 GO:0006810| transport SLC7A4;SLC7A2;ABCB1;SLC7A1 GO:0007568| aging CREB1;ARG1 GO:0002376| immune system process TLR4;ARG1;ARG2 GO:0032720| negative regulation of tumor necrosis factor production TLR4;ARG2 GO:0048545| response to steroid hormone stimulus UGT1A1;ARG1 GO:0043086| negative regulation of catalytic activity OAZ2;OAZ3;UGT1A1;OAZ1 GO:0042493| response to drug OTC;ARG1;UGT1A1;CREB1;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ARG1;OPRM1 GO:0001889| liver development OTC;ARG1;UGT1A1 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;CREB1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;ARG1 GO:0002537| nitric oxide production involved in inflammatory response SLC7A2;TLR4 GO:0050727| regulation of inflammatory response ESR1;SLC7A2;TLR4 GO:0045087| innate immune response ARG1;ARG2;TLR4 10300:[DB01183 DB08868] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP4F12;CYP2C8;CYP4F2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;HDAC1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;HDAC1 GO:0010629| negative regulation of gene expression CREB1;HDAC1;ESR1;OPRD1 GO:0042493| response to drug CYP2E1;ABCB1;UGT1A1;HDAC1;CREB1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;HDAC1 GO:0016032| viral reproduction HDAC1;CREB1 GO:0006954| inflammatory response SPHK1;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity SPHK1;TLR4 GO:0006351| transcription, DNA-dependent ESR1;CREB1;HDAC1 GO:0045471| response to ethanol UGT1A1;OPRK1;CYP2E1;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;HDAC1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;HDAC1;SPHK1 GO:0019373| epoxygenase P450 pathway CYP4F2;CYP2C8;CYP2E1;CYP4F12 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;SPHK1 GO:0008152| metabolic process CES1;SPHK1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2E1;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;HDAC1;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;HDAC1 GO:0048511| rhythmic process HDAC1;CREB1 GO:0048146| positive regulation of fibroblast proliferation SPHK1;ESR1 GO:0006338| chromatin remodeling ESR1;HDAC1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C8 GO:0032732| positive regulation of interleukin-1 production HDAC1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;S1PR5;OPRD1;OPRM1 GO:0017144| drug metabolic process CYP2E1;CYP4F12;CYP3A4;UGT1A1;CYP4F2;CYP2C8 GO:0097267| CYP2C8;CYP4F2 GO:0007165| signal transduction CREB1;TLR4;S1PR5;OPRK1;ESR1;OPRM1;OPRD1;SPHK1 10301:[DB01183 DB00519] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes CES1 common pathways GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0009636| response to toxin CES1 GO:0006811| ion transport SLCO1A2;SLC15A2;SLC15A1 GO:0030855| epithelial cell differentiation CES1 GO:0055085| transmembrane transport SLC15A2;SLCO1A2;SLC15A1;ABCB1 GO:0008152| metabolic process CES1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0051791| medium-chain fatty acid metabolic process CES1 GO:0007586| digestion UGT1A1;SLC15A1 GO:0006695| cholesterol biosynthetic process CES1 GO:0090122| cholesterol ester hydrolysis involved in cholesterol transport CES1 10302:[DB01183 DB03397] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03397|Uridine-Diphosphate-N-Acetylglucosamine glmU;UAP1;murA;GALE;glmU;EXTL2;MGAT1 common genes common pathways GO:0008152| metabolic process UAP1;CES1;UGT1A1 10303:[DB01183 DB06962] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06962|(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone TPSB2 common genes common pathways 10304:[DB01183 DB06928] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways GO:0008152| metabolic process CES1;FOLH1;UGT1A1 10305:[DB01183 DB06376] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06376|CHGN111 CLK1 common genes common pathways GO:0006468| protein phosphorylation CLK1;CREB1 10306:[DB01183 DB12248] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12248|Tulobuterol ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0007165| signal transduction OPRM1;OPRD1;ESR1;ADRB2;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRM1;OPRD1;OPRK1 GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 10307:[DB01183 DB01084] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01084|Emedastine HRH1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;ESR1;OPRK1 GO:0008542| visual learning HRH1;CREB1 GO:0006954| inflammatory response HRH1;TLR4 GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HRH1;OPRD1;OPRM1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;HRH1;OPRD1 10308:[DB01183 DB11327] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;CREB1;UGT1A1;ABCB1 GO:0010629| negative regulation of gene expression CREB1;NOS2;ESR1;OPRD1 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;NOS2;CYP2C8 GO:0009617| response to bacterium NOS2;TLR4 GO:0006954| inflammatory response PTGS2;TLR4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;NOS2;OPRM1;PTGS2 GO:0007623| circadian rhythm NOS2;CREB1 GO:0019233| sensory perception of pain OPRK1;OPRD1;PTGS2;OPRM1 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0001666| response to hypoxia CREB1;NOS2 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory PTGS2;CREB1 GO:0007568| aging CREB1;PTGS2 GO:0098869| PTGS2;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 10309:[DB01183 DB06083] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06083|Tapinarof IL12B;IL2;IL6;CXCL8 common genes common pathways GO:0030890| positive regulation of B cell proliferation IL2;TLR4 GO:0010628| positive regulation of gene expression TLR4;IL6 GO:0010033| response to organic substance CREB1;UGT1A1;IL12B GO:0008285| negative regulation of cell proliferation IL6;CXCL8;OPRM1 GO:0044267| cellular protein metabolic process IL6;ALB GO:0002376| immune system process IL2;TLR4 GO:0032755| positive regulation of interleukin-6 production IL6;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;CXCL8;OPRK1;TLR4;CREB1 GO:0032722| positive regulation of chemokine production IL6;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CXCL8;OPRK1;IL2 GO:0051384| response to glucocorticoid stimulus UGT1A1;IL6 GO:0032735| positive regulation of interleukin-12 production IL12B;TLR4 GO:0050729| positive regulation of inflammatory response IL12B;IL2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration IL2;OPRM1;ESR1 GO:0032700| negative regulation of interleukin-17 production IL12B;TLR4 GO:0006954| inflammatory response TLR4;CXCL8;IL6 GO:0032609| interferon-gamma production IL12B;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IL6 GO:0006955| immune response TLR4;IL6;CXCL8;IL2;OPRK1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;ESR1 GO:0032760| positive regulation of tumor necrosis factor production IL12B;TLR4 GO:0006953| acute-phase response UGT1A1;IL6 GO:0051607| defense response to virus IL12B;IL6;OPRK1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;IL6;CREB1 GO:0043687| post-translational protein modification ALB;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;IL2;IL6;ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;IL6;IL12B;CXCL8;TLR4 GO:0050829| defense response to Gram-negative bacterium IL6;IL12B;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;IL6 GO:0045672| positive regulation of osteoclast differentiation CREB1;IL12B GO:0043066| negative regulation of apoptotic process IL6;IL2;ALB GO:0042346| positive regulation of NF-kappaB import into nucleus IL12B;TLR4 GO:0042088| T-helper 1 type immune response TLR4;IL12B GO:0032733| positive regulation of interleukin-10 production IL12B;TLR4 GO:0050671| positive regulation of lymphocyte proliferation TLR4;IL12B GO:0032729| positive regulation of interferon-gamma production TLR4;IL2;IL12B GO:0045471| response to ethanol IL2;OPRK1;UGT1A1;OPRM1 GO:0019233| sensory perception of pain OPRK1;IL12B;OPRD1;OPRM1 10310:[DB01183 DB07288] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways GO:0030154| cell differentiation FLT1;CREB1 GO:0006468| protein phosphorylation CREB1;FLT1 GO:0010863| positive regulation of phospholipase C activity FLT1;ESR1 10311:[DB01183 DB02445] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 10312:[DB01183 DB05944] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05944|Varlitinib ERBB2;EGFR common genes common pathways GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TLR4;CREB1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;ERBB2;CREB1 GO:0001889| liver development UGT1A1;EGFR GO:0042060| wound healing OPRM1;ERBB2;EGFR GO:0007623| circadian rhythm EGFR;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;ESR1;EGFR GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;EGFR GO:0006355| regulation of transcription, DNA-dependent ESR1;ERBB2;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;ERBB2;CREB1;TLR4;OPRK1;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TLR4;ESR1;OPRM1 GO:0006468| protein phosphorylation ERBB2;CREB1;EGFR GO:0071392| cellular response to estradiol stimulus ESR1;EGFR;UGT1A1 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0071363| cellular response to growth factor stimulus EGFR;CREB1;ERBB2;OPRD1 GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0048146| positive regulation of fibroblast proliferation ESR1;EGFR GO:0010628| positive regulation of gene expression TLR4;ERBB2 GO:0070374| positive regulation of ERK1 and ERK2 cascade EGFR;TLR4;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;EGFR 10313:[DB01183 DB05009] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05009|Apadenoson ADORA2A common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4;ADORA2A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADORA2A;OPRK1 GO:0008285| negative regulation of cell proliferation ADORA2A;OPRM1 GO:0042755| eating behavior OPRK1;ADORA2A;OPRM1;OPRD1 GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0051881| regulation of mitochondrial membrane potential OPRD1;ADORA2A GO:0007626| locomotory behavior OPRK1;ADORA2A;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA2A;OPRM1 GO:0006954| inflammatory response TLR4;ADORA2A GO:0007600| sensory perception OPRM1;ADORA2A;OPRK1 GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0042493| response to drug ADORA2A;CREB1;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;CREB1;ESR1 10314:[DB01183 DB12518] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12518|Raclopride DRD2 common genes common pathways GO:0042220| response to cocaine OPRM1;DRD2;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0009636| response to toxin CES1;DRD2 GO:0007409| axonogenesis DRD2;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0001666| response to hypoxia DRD2;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;OPRM1;OPRD1 GO:0007165| signal transduction OPRK1;DRD2;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:1900273| CREB1;DRD2 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0042493| response to drug DRD2;ABCB1;UGT1A1;CREB1 GO:0035094| response to nicotine CREB1;DRD2 GO:0008542| visual learning CREB1;DRD2 GO:0043278| response to morphine OPRK1;DRD2;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;DRD2;OPRK1 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0048148| behavioral response to cocaine DRD2;OPRK1 GO:0007626| locomotory behavior DRD2;OPRK1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD2 10315:[DB01183 DB05281] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0035094| response to nicotine CREB1;BCL2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;BCL2 GO:0051607| defense response to virus BCL2;OPRK1 GO:0042981| regulation of apoptotic process BCL2;ESR1;CREB1 GO:0002576| platelet degranulation ALB;TUBA4A GO:0009314| response to radiation BCL2;OPRM1;OPRK1 GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0008285| negative regulation of cell proliferation BCL2;OPRM1 GO:0008584| male gonad development BCL2;ESR1 GO:0030890| positive regulation of B cell proliferation BCL2;TLR4 GO:0000086| G2/M transition of mitotic cell cycle TUBA4A;ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;BCL2 GO:0051881| regulation of mitochondrial membrane potential BCL2;OPRD1 GO:0007409| axonogenesis BCL2;CREB1 GO:0009636| response to toxin CES1;BCL2 GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;OPRD1 GO:0071456| cellular response to hypoxia OPRD1;BCL2 GO:0040018| positive regulation of multicellular organism growth CREB1;BCL2 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2 10316:[DB01183 DB11311] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11311|Prothrombin FGA;FGB;F13A1;CPB2;F10 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;ESR1;FGB;TLR4;CREB1;FGA;OPRK1 GO:0002376| immune system process FGB;FGA;TLR4 GO:0002224| toll-like receptor signaling pathway TLR4;FGA;FGB GO:0044267| cellular protein metabolic process ALB;FGA GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;FGB;TLR4;FGA GO:0045087| innate immune response FGA;TLR4;FGB GO:0002576| platelet degranulation FGB;FGA;F13A1;ALB GO:0043687| post-translational protein modification ALB;FGA GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CPB2 10317:[DB01183 DB08391] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0008152| metabolic process CES1;PDE10A;UGT1A1 GO:0007165| signal transduction PDE10A;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway PDE10A;OPRD1;OPRM1;OPRK1 10318:[DB01183 DB07775] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 10319:[DB01183 DB06439] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06439|Tyloxapol LPL common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;ABCB1;LPL GO:0006629| lipid metabolic process LPL;CYP3A4 GO:0050729| positive regulation of inflammatory response TLR4;LPL 10320:[DB01183 DB12702] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12702|Velusetrag HTR4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HTR4;OPRD1;OPRK1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;HTR4;ESR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;HTR4;OPRM1 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR4;OPRK1 10321:[DB01183 DB03554] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03554|5-Iodouracil DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;DPYD;CYP3A4 10322:[DB01183 DB08473] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08473|5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole CSNK2A1 common genes common pathways GO:0048511| rhythmic process CSNK2A1;CREB1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;CSNK2A1;ESR1;CREB1;TLR4;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CSNK2A1;CREB1 GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 10323:[DB01183 DB04356] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0007626| locomotory behavior OPRM1;HPRT1;OPRK1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2 10324:[DB01183 DB08056] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0006468| protein phosphorylation CREB1;LCK GO:0016032| viral reproduction CREB1;LCK GO:0042493| response to drug CREB1;UGT1A1;LCK;ABCB1 GO:0045087| innate immune response LCK;TLR4 10325:[DB01183 DB00376] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007165| signal transduction CHRM1;ESR1;CHRM2;OPRM1;CHRM5;OPRD1;OPRK1;CHRM4;CREB1;TLR4;CHRM3 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CHRM5;OPRD1;CHRM1;CHRM2;CHRM4;OPRK1;CHRM3 GO:0007586| digestion UGT1A1;CHRM3 10326:[DB01183 DB00901] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00901|Bitolterol ADRB2 common genes common pathways GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADRB2;OPRK1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0007165| signal transduction ESR1;ADRB2;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 10327:[DB01183 DB07167] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways GO:0045087| innate immune response CSF1R;TLR4 GO:0043066| negative regulation of apoptotic process CSF1R;ALB GO:0006954| inflammatory response TLR4;CSF1R GO:0007165| signal transduction OPRK1;CREB1;TLR4;CSF1R;OPRM1;OPRD1;ESR1 GO:0002376| immune system process CSF1R;TLR4 GO:0006468| protein phosphorylation CREB1;CSF1R GO:0008285| negative regulation of cell proliferation OPRM1;CSF1R GO:0007411| axon guidance CSF1R;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CSF1R;TLR4 10328:[DB01183 DB01303] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A7 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE3A;ADORA1;ADORA2A;OPRM1;OPRD1;PDE4A GO:0032732| positive regulation of interleukin-1 production TLR4;HDAC2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADORA1;OPRK1 GO:0006338| chromatin remodeling ESR1;HDAC2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0007165| signal transduction ESR1;OPRM1;PDE4A;OPRD1;ADORA1;CREB1;ADORA2A;TLR4;PDE3A;OPRK1 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0015711| organic anion transport SLCO1A2;SLC22A7 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0006811| ion transport SLCO1A2;SLC22A7 GO:0042755| eating behavior OPRD1;OPRM1;ADORA2A;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;ADORA1;OPRM1;OPRD1 GO:0042220| response to cocaine OPRM1;HDAC2;OPRK1 GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0055085| transmembrane transport SLC22A7;SLCO1A2;ABCB1 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1 GO:0001666| response to hypoxia CREB1;ADORA1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HDAC2 GO:0008285| negative regulation of cell proliferation OPRM1;ADORA2A;ADORA1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0048511| rhythmic process CREB1;HDAC2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2;HDAC2 GO:0006351| transcription, DNA-dependent ESR1;HDAC2;CREB1 GO:0097190| apoptotic signaling pathway TLR4;ADORA1 GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA2A;ADORA1;OPRM1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus PDE3A;CREB1;HDAC2 GO:0043066| negative regulation of apoptotic process ALB;ADORA1;PDE3A;HDAC2 GO:0007626| locomotory behavior OPRM1;OPRK1;ADORA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;HDAC2;CREB1;TLR4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PDE3A GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;HDAC2 GO:0048149| behavioral response to ethanol HDAC2;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;HDAC2 GO:0042493| response to drug ABCB1;UGT1A1;PDE3A;ADORA2A;CREB1;HDAC2;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent HDAC2;ESR1;CREB1;ADORA2A GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0006954| inflammatory response ADORA1;TLR4;ADORA2A GO:0007600| sensory perception OPRM1;ADORA2A;OPRK1 GO:0035094| response to nicotine CREB1;HDAC2 GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;HDAC2 10329:[DB01183 DB08341] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0042220| response to cocaine OPRM1;OPRK1;PTK2B GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PTK2B GO:0008285| negative regulation of cell proliferation PTK2B;OPRM1 GO:0001666| response to hypoxia PTK2B;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration PTK2B;ESR1;OPRM1 GO:0006468| protein phosphorylation CREB1;PTK2B GO:0030154| cell differentiation CREB1;PTK2B GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;PTK2B;TLR4;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;PTK2B;TLR4 GO:0002376| immune system process TLR4;PTK2B GO:0042493| response to drug CREB1;UGT1A1;PTK2B;ABCB1 GO:0046330| positive regulation of JNK cascade PTK2B;TLR4 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;PTK2B GO:0045471| response to ethanol OPRM1;OPRK1;PTK2B;UGT1A1 GO:0045087| innate immune response TLR4;PTK2B GO:0043066| negative regulation of apoptotic process ALB;PTK2B GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity PTK2B;OPRM1 10330:[DB01183 DB13627] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 10331:[DB01183 DB05036] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways GO:0050821| protein stabilization PTGES3;CREB1 GO:0006468| protein phosphorylation SCYL1;CREB1 GO:0071456| cellular response to hypoxia OPRD1;TERT GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;PTGES3;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;TERT GO:0006351| transcription, DNA-dependent CREB1;SCYL1;ESR1 GO:0006805| xenobiotic metabolic process PTGES3;CES1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process TERT;ALB GO:0006629| lipid metabolic process CYP3A4;PTGES3 GO:0010629| negative regulation of gene expression CREB1;ESR1;TERT;OPRD1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;SCYL1 10332:[DB01183 DB07969] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;MET;ESR1 GO:0007165| signal transduction OPRD1;MET;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0006468| protein phosphorylation CREB1;MET 10333:[DB01183 DB03902] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03902|Oxalic Acid SRC;SLCO2B1;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;CES1 GO:0006811| ion transport SLC22A8;SLCO1A2;SLCO2B1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;SRC;OPRM1 GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLCO1A2;SLC22A8 GO:0010628| positive regulation of gene expression TLR4;SRC GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1;SRC GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1A2 GO:0007411| axon guidance CREB1;SRC GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB;SLCO2B1 GO:0036120| CREB1;SRC GO:0071456| cellular response to hypoxia OPRD1;SRC GO:0006468| protein phosphorylation SRC;CREB1 GO:0002376| immune system process SRC;TLR4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;SRC GO:0045893| positive regulation of transcription, DNA-dependent ESR1;SRC;CREB1 GO:0042493| response to drug SRC;UGT1A1;CREB1;ABCB1 GO:0016032| viral reproduction CREB1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0071560| cellular response to transforming growth factor beta stimulus SRC;CREB1 GO:0060065| uterus development ESR1;SRC GO:0071398| cellular response to fatty acid CREB1;SRC GO:0030520| intracellular estrogen receptor signaling pathway ESR1;SRC GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;SRC GO:0043065| positive regulation of apoptotic process SRC;CREB1 GO:0045087| innate immune response TLR4;SRC 10334:[DB01183 DB04249] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04249|Zinc Substituted Heme C CYCS common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYCS;CYP3A4 10335:[DB01183 DB01890] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;IGF1;PPARA;ESR1 GO:0002576| platelet degranulation IGF1;ALB GO:0043066| negative regulation of apoptotic process ALB;IGF1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;ESR1 GO:0006629| lipid metabolic process CYP3A4;PPARA GO:0042060| wound healing OPRM1;PPARA GO:0006351| transcription, DNA-dependent CREB1;ESR1;PPARA GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARA GO:0042752| regulation of circadian rhythm PPARA;CREB1 GO:0006355| regulation of transcription, DNA-dependent PPARA;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;IGF1;ESR1;PPARA GO:0043491| protein kinase B signaling cascade IGF1;CREB1 GO:1901215| CREB1;PPARA GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;IGF1;OPRK1 GO:0050821| protein stabilization CREB1;IGF1 GO:0048146| positive regulation of fibroblast proliferation IGF1;ESR1 GO:1904646| IGF1;TLR4 GO:0010628| positive regulation of gene expression TLR4;IGF1 GO:0001666| response to hypoxia CREB1;PPARA GO:0048511| rhythmic process PPARA;CREB1 GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0044267| cellular protein metabolic process IGF1;ALB GO:0000187| activation of MAPK activity IGF1;TLR4 10336:[DB01183 DB08237] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08237|2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) POLK common genes common pathways 10337:[DB01183 DB14014] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14014|SR-9011 NR1D2;NR1D1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1D1;CREB1;NR1D2;ESR1 GO:2000505| regulation of energy homeostasis OPRK1;NR1D2 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR1D1;NR1D2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1D2;ESR1;NR1D1 GO:0042752| regulation of circadian rhythm NR1D1;CREB1;NR1D2 GO:0007623| circadian rhythm CREB1;NR1D1 GO:0043401| steroid hormone mediated signaling pathway NR1D1;NR1D2;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NR1D2;CREB1;NR1D1 GO:0050727| regulation of inflammatory response TLR4;ESR1;NR1D2 GO:0071222| cellular response to lipopolysaccharide NR1D1;TLR4;OPRK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1D1;ESR1;NR1D2 GO:0048511| rhythmic process NR1D1;CREB1;NR1D2 GO:0030154| cell differentiation NR1D1;CREB1 10338:[DB01183 DB00535] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0042742| defense response to bacterium TLR4;MPO GO:0055114| oxidation-reduction process MPO;CYP3A4;CYP2C8 GO:0032094| response to food OPRM1;MPO GO:0007586| digestion UGT1A1;SLC15A1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MPO;OPRM1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport SLC22A8;SLC15A2;SLC22A5;SLCO1A2;ABCB1;SLC15A1;SLC22A6 GO:0006811| ion transport SLCO1A2;SLC22A8;SLC22A5;SLC15A2;SLC15A1 GO:0009636| response to toxin SLC22A8;CES1 GO:0015711| organic anion transport SLCO1A2;SLC22A5;SLC22A6 GO:0007568| aging MPO;CREB1 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;SLC22A6;ALB 10339:[DB01183 DB05070] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05070|ADX10059 GRM5 common genes common pathways GO:0007626| locomotory behavior OPRK1;GRM5;OPRM1 GO:0007268| synaptic transmission GRM5;OPRD1;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;GRM5;OPRM1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;GRM5;ESR1 GO:1904646| GRM5;TLR4 10340:[DB01183 DB05481] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways GO:0002576| platelet degranulation ALB;SERPINA1 GO:0006953| acute-phase response UGT1A1;SERPINA1 GO:0043687| post-translational protein modification SERPINA1;ALB GO:0044267| cellular protein metabolic process ALB;SERPINA1 10341:[DB01183 DB14520] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:0042060| wound healing ITGB3;OPRM1 GO:0002576| platelet degranulation ITGB3;ALB;TF GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1;CALR GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CALR GO:0006355| regulation of transcription, DNA-dependent CALR;CREB1;ESR1 GO:0043687| post-translational protein modification ALB;TF GO:0016032| viral reproduction TFRC;CREB1;ITGB3 GO:0032355| response to estradiol stimulus ESR1;CALR GO:0050821| protein stabilization CALR;CREB1 GO:0006898| receptor-mediated endocytosis ALB;CALR;TFRC GO:0006811| ion transport TF;SLCO1A2 GO:0001895| retina homeostasis TF;ALB GO:0044267| cellular protein metabolic process TF;ALB GO:0010628| positive regulation of gene expression TLR4;CALR GO:0030890| positive regulation of B cell proliferation TLR4;TFRC GO:1990830| TFRC;CREB1 GO:0010033| response to organic substance CREB1;CALR;UGT1A1 10342:[DB01183 DB04991] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04991|XL784 ADAM10 common genes common pathways GO:0044267| cellular protein metabolic process ADAM10;ALB GO:0006468| protein phosphorylation CREB1;ADAM10 GO:0043687| post-translational protein modification ALB;ADAM10 10343:[DB01183 DB00723] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00723|Methoxamine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1;CREB1;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;ADRA1B;ADRA1D;ADRA1A;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ADRA1A;TLR4 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;ESR1;OPRM1;ADRA1B GO:0007568| aging CREB1;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;ADRA1B;ADRA1D;OPRK1;ADRA1A GO:0007165| signal transduction ADRA1B;ESR1;OPRD1;OPRM1;OPRK1;ADRA1A;TLR4;CREB1;ADRA1D 10344:[DB01183 DB00025] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0006953| acute-phase response UGT1A1;F2 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;CALR GO:0042493| response to drug ABCB1;CALR;CREB1;UGT1A1 GO:0043687| post-translational protein modification PROC;ALB GO:0055114| oxidation-reduction process CYP3A4;PHYH;CYP2C8 GO:0009314| response to radiation OPRM1;OPRK1;HSPA5 GO:0002576| platelet degranulation ALB;VWF GO:0043066| negative regulation of apoptotic process PROC;ALB;HSPA5 GO:0042981| regulation of apoptotic process CREB1;CALR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CALR GO:1990090| HSPA5;CREB1 GO:0006629| lipid metabolic process LRP1;CYP3A4 GO:0001889| liver development PROC;UGT1A1 GO:0010628| positive regulation of gene expression CALR;TLR4 GO:1904646| TLR4;LRP1 GO:0010033| response to organic substance CALR;CREB1;UGT1A1 GO:0044267| cellular protein metabolic process PROC;ALB;F2 GO:0042220| response to cocaine HSPA5;OPRK1;OPRM1 GO:0006898| receptor-mediated endocytosis ASGR2;ALB;LRP1;CALR GO:0050821| protein stabilization CALR;CREB1 GO:0007186| G-protein coupled receptor signaling pathway F2;OPRK1;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus CALR;ESR1 GO:0007568| aging CREB1;LRP1;CANX 10345:[DB01183 DB07086] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07086|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL NCOA2;ESR1 common genes ESR1 common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NCOA2;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;NCOA2 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process CREB1;NCOA2 10346:[DB01183 DB01365] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1D;ADRA1A;OPRK1;OPRD1;OPRM1;ESR1;ADRA1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;ESR1;TLR4;CREB1 GO:0042493| response to drug ABCB1;ADRA1A;UGT1A1;CREB1 GO:0007568| aging CREB1;ADRB3;ADRA1A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;OPRM1;ESR1;ADRA1A;ADRA1D GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;ADRA2A;ADRB3;OPRK1;ADRB1;ADRA1A;ADRA2C;ADRB2;ADRA2B;OPRM1;OPRD1;ADRA1B GO:0007165| signal transduction ADRA1B;ESR1;ADRA2C;ADRB2;ADRA2B;OPRM1;OPRD1;ADRA2A;OPRK1;ADRB3;ADRA1A;ADRB1;CREB1;TLR4;ADRA1D GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TLR4;OPRM1 GO:0042755| eating behavior ADRB3;OPRK1;OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADRA2C;OPRK1 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:1904646| TLR4;ADRB2 10347:[DB01183 DB07853] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07853|[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE SLK;CAMK2D;STK26 common genes common pathways GO:0042981| regulation of apoptotic process ESR1;STK26;CREB1;SLK GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;CAMK2D GO:0009267| cellular response to starvation ALB;STK26 GO:0030154| cell differentiation CREB1;CAMK2D GO:0006468| protein phosphorylation SLK;CREB1;STK26;CAMK2D 10348:[DB01183 DB05085] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05085|TM30339 NPY4R common genes common pathways GO:0007268| synaptic transmission NPY4R;OPRK1;OPRM1;OPRD1 GO:0007586| digestion NPY4R;UGT1A1 GO:0007218| neuropeptide signaling pathway NPY4R;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction OPRK1;NPY4R;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;NPY4R;OPRK1 10349:[DB01183 DB09211] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGER4;TLR4 GO:0032496| response to lipopolysaccharide PTGER4;UGT1A1;TLR4;PTGER2;OPRM1;PTGER1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;PTGER3;ESR1;OPRK1 GO:0006955| immune response OPRD1;OPRK1;PTGER4;TLR4 GO:0007165| signal transduction PTGER2;ESR1;PTGER3;OPRD1;PTGER1;OPRM1;OPRK1;TLR4;CREB1;PTGER4 GO:0050729| positive regulation of inflammatory response PTGER4;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;PTGER1;PTGER3;OPRD1;PTGER2;PTGER4;OPRK1 10350:[DB01183 DB00219] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00219|Oxyphenonium CHRM1 common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;CHRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM1;OPRK1 10351:[DB01183 DB13928] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes ALB common pathways GO:0008152| metabolic process UGT1A1;AMY1A;CES1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0006629| lipid metabolic process CYP3A4;LPL GO:0007586| digestion UGT1A1;AMY1A GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0019233| sensory perception of pain OPRK1;OPRM1;MME;OPRD1 GO:0042493| response to drug CREB1;UGT1A1;LPL;ABCB1 GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0007165| signal transduction TLR4;CREB1;GLP1R;OPRK1;ESR1;OPRD1;OPRM1 GO:0015711| organic anion transport SLCO1B1;SLCO1B3;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0050729| positive regulation of inflammatory response LPL;TLR4 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;GLP1R GO:0043069| negative regulation of programmed cell death ALB GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;OPRM1;ESR1 GO:0001666| response to hypoxia CREB1;DPP4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SLCO1A2;SLCO1B3;SLCO1B1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;SLCO1A2;ABCB1 10352:[DB01183 DB06771] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;ABCB1;CREB1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 10353:[DB01183 DB03347] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03347|Triethyl Phosphate TP53 common genes common pathways GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1;TP53 GO:0014070| response to organic cyclic compound TP53;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;TP53 GO:0016579| protein deubiquitination ESR1;TP53 GO:0048511| rhythmic process TP53;CREB1 GO:0010628| positive regulation of gene expression TP53;TLR4 GO:0007568| aging CREB1;TP53 GO:0030154| cell differentiation CREB1;TP53 GO:0071456| cellular response to hypoxia TP53;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;TP53;ESR1 GO:0042493| response to drug CREB1;TP53;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;TP53;CREB1 GO:0016032| viral reproduction CREB1;TP53 GO:0006351| transcription, DNA-dependent ESR1;CREB1;TP53 GO:0045471| response to ethanol OPRM1;OPRK1;TP53;UGT1A1 GO:0042060| wound healing OPRM1;TP53 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP53;ESR1 GO:0042981| regulation of apoptotic process CREB1;TP53;ESR1 GO:0043066| negative regulation of apoptotic process ALB;TP53 GO:0043065| positive regulation of apoptotic process CREB1;TP53 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TP53;TLR4;CREB1;ESR1 10354:[DB01183 DB01152] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01152|Candicidin CYP3A4 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 10355:[DB01183 DB00354] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;CHRM1;ESR1;OPRM1;HRH1;OPRD1 GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CHRM1;OPRD1;HRH1;OPRM1 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;HRH1;OPRD1;OPRM1 10356:[DB01183 DB05399] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05399|Succinobucol VCAM1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;VCAM1;UGT1A1;TLR4 GO:0045471| response to ethanol VCAM1;OPRM1;UGT1A1;OPRK1 GO:0055114| oxidation-reduction process VCAM1;CYP3A4;CYP2C8 GO:0016032| viral reproduction VCAM1;CREB1 GO:0035094| response to nicotine VCAM1;CREB1 GO:0007568| aging VCAM1;CREB1 GO:0001666| response to hypoxia VCAM1;CREB1 GO:0007584| response to nutrient UGT1A1;VCAM1 10357:[DB01183 DB02698] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR GO:0006810| transport ABCB1;TTR 10358:[DB01183 DB08342] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08342|S-PALMITOYL-L-CYSTEINE TRAPPC6A;TRAPPC3;TRAPPC6B;TRAPPC5;TRAPPC4;TRAPPC1 common genes common pathways 10359:[DB01183 DB02918] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02918|Zardaverine PDE4D common genes common pathways GO:0071222| cellular response to lipopolysaccharide PDE4D;TLR4;OPRK1 GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;PDE4D;OPRM1;ESR1 GO:0007568| aging PDE4D;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;PDE4D;OPRD1 10360:[DB01183 DB01752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PRMT1;SETD7;CREB1;PRMT3;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;SETD7;CREB1 GO:0045471| response to ethanol OPRM1;SETD7;UGT1A1;OPRK1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;SETD7 GO:0008152| metabolic process CES1;UGT1A1;DPH5 GO:1900745| OPRK1;PRMT1 10361:[DB01183 DB08610] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08610|N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE PDK2 common genes common pathways GO:0006468| protein phosphorylation PDK2;CREB1 10362:[DB01183 DB01970] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways GO:0043951| negative regulation of cAMP-mediated signaling OPRM1;PDE3B GO:0007165| signal transduction PDE3B;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway PDE3B;OPRM1;OPRD1;OPRK1 10363:[DB01183 DB07162] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;JAK2 GO:0032760| positive regulation of tumor necrosis factor production JAK2;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;JAK2;TLR4 GO:0043065| positive regulation of apoptotic process JAK2;CREB1 GO:0050727| regulation of inflammatory response JAK2;TLR4;ESR1 GO:0045087| innate immune response JAK2;TLR4 GO:0042981| regulation of apoptotic process ESR1;JAK2;CREB1 GO:0008285| negative regulation of cell proliferation JAK2;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;JAK2;OPRK1 GO:0050729| positive regulation of inflammatory response JAK2;TLR4 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process JAK2;TLR4 GO:0030154| cell differentiation CREB1;JAK2 GO:0006468| protein phosphorylation CREB1;JAK2 GO:0007204| elevation of cytosolic calcium ion concentration JAK2;ESR1;OPRM1 GO:0002376| immune system process JAK2;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;JAK2;ESR1;OPRM1 GO:0007165| signal transduction OPRK1;JAK2;TLR4;CREB1;OPRD1;OPRM1;ESR1 10364:[DB01183 DB00756] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes ESR1 common pathways GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0055114| oxidation-reduction process SDHD;CYP3A4;GLUD1;CYP2C8 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0060065| uterus development ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 10365:[DB01183 DB04450] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04450|Heptyl 1-Thiohexopyranoside RHO;fpr;acpP common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;RHO;OPRK1 GO:0006468| protein phosphorylation CREB1;RHO GO:0007165| signal transduction CREB1;TLR4;RHO;OPRK1;ESR1;OPRM1;OPRD1 10366:[DB01183 DB07626] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07626|4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0007165| signal transduction CREB1;TLR4;PLAU;OPRK1;OPRM1;OPRD1;ESR1 GO:0001666| response to hypoxia PLAU;CREB1 10367:[DB01183 DB08257] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways GO:0009636| response to toxin CES1;EPHX2 GO:0010628| positive regulation of gene expression TLR4;EPHX2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;EPHX2 GO:0006954| inflammatory response TLR4;EPHX2 GO:0008152| metabolic process UGT1A1;EPHX2;CES1 GO:0006805| xenobiotic metabolic process CYP2C8;EPHX2;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0006629| lipid metabolic process EPHX2;CYP3A4 10368:[DB01183 DB04721] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04721|N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;CSNK2A1;OPRM1;ESR1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0048511| rhythmic process CSNK2A1;CREB1 GO:0006351| transcription, DNA-dependent CSNK2A1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CSNK2A1;CREB1 10369:[DB01183 DB07991] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes ESR1 common pathways GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;OPRK1 GO:0002064| epithelial cell development ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;OPRK1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 10370:[DB01183 DB06635] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06635|Otamixaban F10 common genes common pathways 10371:[DB01183 DB05298] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05298|Tetomilast PDE4D common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;PDE4D;OPRD1 GO:0007568| aging CREB1;PDE4D GO:0007165| signal transduction ESR1;OPRM1;PDE4D;OPRD1;CREB1;TLR4;OPRK1 GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;PDE4D 10372:[DB01183 DB05562] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05562|Naluzotan HTR1A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR1A;OPRM1;OPRD1 GO:0007610| behavior HTR1A;OPRK1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;HTR1A;ESR1;OPRD1;OPRM1 10373:[DB01183 DB04339] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04339|Carbocisteine GSTP1 common genes common pathways GO:0070373| negative regulation of ERK1 and ERK2 cascade GSTP1;TLR4 GO:0009636| response to toxin GSTP1;CES1 GO:0032355| response to estradiol stimulus ESR1;GSTP1 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0098869| GSTP1;ALB GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0045471| response to ethanol OPRM1;UGT1A1;GSTP1;OPRK1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;GSTP1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;GSTP1 GO:0008152| metabolic process GSTP1;UGT1A1;CES1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 10374:[DB01183 DB05101] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05101|Matuzumab EGFR common genes common pathways GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0071363| cellular response to growth factor stimulus OPRD1;EGFR;CREB1 GO:0050729| positive regulation of inflammatory response EGFR;TLR4 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1;ESR1 GO:0006468| protein phosphorylation EGFR;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TLR4;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;EGFR GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;EGFR;CREB1;TLR4 GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;EGFR;TLR4 GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0042060| wound healing OPRM1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1 GO:0007623| circadian rhythm EGFR;CREB1 GO:0001889| liver development UGT1A1;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;EGFR;ESR1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGFR;CREB1 10375:[DB01183 DB06454] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 GO:0042220| response to cocaine OPRM1;DRD3;OPRK1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;DRD2 GO:0001666| response to hypoxia DRD2;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway DRD2;OPRK1;DRD3;OPRM1;OPRD1;HTR1A GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:1900273| CREB1;DRD2 GO:0007165| signal transduction OPRD1;OPRM1;HTR1A;ESR1;TLR4;DRD3;CREB1;DRD2;OPRK1 GO:0007610| behavior HTR1A;OPRK1 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0042493| response to drug CREB1;DRD3;UGT1A1;ABCB1;DRD2 GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning DRD2;CREB1;DRD3 GO:0043278| response to morphine DRD3;OPRK1;DRD2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0045471| response to ethanol DRD3;UGT1A1;OPRK1;DRD2;OPRM1 GO:0048148| behavioral response to cocaine DRD3;DRD2;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;OPRM1 GO:0007626| locomotory behavior OPRK1;DRD2;DRD3;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TLR4;DRD3;CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 10376:[DB01183 DB08389] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;PDE10A GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;PDE10A GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;PDE10A 10377:[DB01183 DB00677] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;TF GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0042493| response to drug BCHE;UGT1A1;CREB1;ABCB1 GO:0043687| post-translational protein modification TF;ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport TF;SLCO1A2 GO:0001895| retina homeostasis TF;ALB GO:0044267| cellular protein metabolic process TF;ALB 10378:[DB01183 DB05806] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05806|Cositecan TOP1 common genes common pathways GO:0042493| response to drug TOP1;CREB1;UGT1A1;ABCB1 GO:0016032| viral reproduction CREB1;TOP1 GO:0007623| circadian rhythm TOP1;CREB1 GO:0048511| rhythmic process CREB1;TOP1 GO:0006338| chromatin remodeling ESR1;TOP1 10379:[DB01183 DB04633] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways 10380:[DB01183 DB13926] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13926|Cenegermin NTRK1 common genes common pathways GO:1990090| CREB1;NTRK1 GO:0009314| response to radiation OPRM1;NTRK1;OPRK1 GO:0043066| negative regulation of apoptotic process NTRK1;ALB GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1;NTRK1 GO:0007623| circadian rhythm CREB1;NTRK1 GO:0035094| response to nicotine CREB1;NTRK1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NTRK1;TLR4 GO:1901215| CREB1;NTRK1 GO:0042493| response to drug ABCB1;UGT1A1;NTRK1;CREB1 GO:0006468| protein phosphorylation NTRK1;CREB1 GO:0030154| cell differentiation NTRK1;CREB1 GO:0007568| aging NTRK1;CREB1 GO:0071363| cellular response to growth factor stimulus CREB1;NTRK1;OPRD1 GO:0007411| axon guidance NTRK1;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;NTRK1 GO:1904646| NTRK1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;NTRK1 10381:[DB01183 DB11323] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;ESR1;TLR4 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRD1;PTGS2;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;PTGS2;OPRM1 GO:0006954| inflammatory response PTGS1;PTGS2;TLR4 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;PTGS2;CYP2C8 GO:0042493| response to drug PTGS2;ABCB1;UGT1A1;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0098869| ALB;PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;PTGS2;ESR1 GO:0007568| aging CREB1;PTGS2 GO:0007613| memory CREB1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0010033| response to organic substance PTGS2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 10382:[DB01183 DB03957] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03957|SP2456 IL2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IL2;CREB1;TLR4 GO:0045471| response to ethanol OPRK1;IL2;UGT1A1;OPRM1 GO:0032729| positive regulation of interferon-gamma production IL2;TLR4 GO:0006955| immune response TLR4;IL2;OPRK1;OPRD1 GO:0002376| immune system process TLR4;IL2 GO:0007204| elevation of cytosolic calcium ion concentration IL2;ESR1;OPRM1 GO:0050729| positive regulation of inflammatory response TLR4;IL2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;IL2 GO:0030890| positive regulation of B cell proliferation TLR4;IL2 10383:[DB01183 DB14544] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1;CYP3A4;CYP2C8;SLCO1A2 common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0042359| vitamin D metabolic process CYP3A4 GO:0001666| response to hypoxia HSD11B2;CREB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;ANXA1 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0002933| CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0009636| response to toxin SLC22A8;CES1 GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0032868| response to insulin stimulus OPRK1;HSD11B2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0055085| transmembrane transport ABCB1;ABCG2;SLCO1A2;SLC22A8 GO:0036378| CYP3A4 GO:0002376| immune system process ANXA1;TLR4 GO:0044849| OPRM1;ANXA1;OPRK1 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 GO:0032870| cellular response to hormone stimulus CYP11B1;CYP11B2;UGT1A1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ANXA1;NR3C1;OPRD1;OPRM1;ESR1 GO:0048545| response to steroid hormone stimulus HSD11B2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP2C8 GO:0015711| organic anion transport SLCO1A2 GO:0051384| response to glucocorticoid stimulus UGT1A1;HSD11B2;ANXA1 GO:0032355| response to estradiol stimulus ANXA1;ESR1 GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ANXA1;OPRK1 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB GO:0045332| phospholipid translocation ABCB1 GO:0008202| steroid metabolic process CYP11B1;CYP11B2;CYP3A7;CYP3A4;UGT1A1;CYP2C8;CYP3A5 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;UGT1A1;NR3C1 GO:0006954| inflammatory response TLR4;ANXA1 GO:0006955| immune response OPRK1;TLR4;CYP11B1;OPRD1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0042493| response to drug ABCG2;ANXA1;HSD11B2;ABCB1;CREB1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0032094| response to food OPRM1;HSD11B2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP11B2;CYP11B1;CYP3A7;CYP2C8;HSD3B1;CYP3A5;HSD11B2 GO:0099040| ABCB1 GO:0043065| positive regulation of apoptotic process ANXA1;CREB1 GO:0050727| regulation of inflammatory response ESR1;ANXA1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NR3C1;ESR1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP3A7;CYP3A5;CYP2C8 GO:0008152| metabolic process UGT1A1;HSD3B1;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;ANXA1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0045087| innate immune response TLR4;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0006082| organic acid metabolic process CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP11B1;CYP11B2 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NR3C1;ESR1 10384:[DB01183 DB14481] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes ALB common pathways GO:0006898| receptor-mediated endocytosis SPARC;CALR;ALB GO:0070588| calcium ion transmembrane transport CACNB2;OPRM1;CACNA1H;PKD1L3;CACNA1D;SLC8A1;CACNB4;NCS1;RYR1;CACNA1C;TRPV6;CACNB3;CACNA1S;CATSPER1;TRPV5;CACNA1G;PKD2L1;RYR3;CACNA1E;CACNB1;CACNA1I;CACNA1A;RYR2;CACNA1F GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0098869| ALB GO:0035729| cellular response to hepatocyte growth factor stimulus CASR;CREB1 GO:0007165| signal transduction CACNA1I;OPRK1;TLR4;CREB1;S100A6;CASR;SPARC;SRI;OPRD1;OPRM1;ESR1;SLC20A1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;RGN GO:0032355| response to estradiol stimulus CALR;ESR1;SLC34A1 GO:0051384| response to glucocorticoid stimulus SPARC;S100B;UGT1A1 GO:0050821| protein stabilization CREB1;CALR;CHP1 GO:0071363| cellular response to growth factor stimulus SPARC;OPRD1;CIB1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CALM2;CALM3;CALM1;CASR;OPRD1;OPRM1 GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation CADPS2;ALB GO:0007613| memory S100B;CREB1 GO:0030154| cell differentiation CIB1;CREB1;CATSPER1;TPT1;CALR3 GO:0007204| elevation of cytosolic calcium ion concentration SLC8A1;CACNA1C;OPRM1;ESR1;CACNA1A;CIB2 GO:0071456| cellular response to hypoxia SLC8A1;S100B;CASR;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway CASR;OPRD1;OPRM1;OPRK1 GO:0007568| aging RGN;CREB1;CANX GO:0006810| transport ABCB1;CACNA1I;CACNB1;CACNA1E;CACNB3;CACNB4;SLC20A2;SRI;SLC20A1 GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0001666| response to hypoxia RYR2;CREB1;SLC8A1;RYR1 GO:1904646| CACNA1A;CACNB1;TLR4 GO:0010628| positive regulation of gene expression CASR;CALR;TLR4 GO:0048146| positive regulation of fibroblast proliferation S100A6;ESR1 GO:0043627| response to estrogen stimulus OPRK1;SLC34A2;ESR1 GO:0007584| response to nutrient UGT1A1;SLC34A1;SLC8A1 GO:0007411| axon guidance CREB1;NRXN1 GO:0010033| response to organic substance CASQ1;CALR;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;CIB1 GO:0006811| ion transport SLC20A2;PKD1L3;SLC34A3;CACNB4;CACNA1D;SLC8A1;SLC34A1;CACNA1C;RYR1;CACNB2;SLC20A1;CACNA1H;SLCO1A2;CACNB1;CACNA1A;CACNA1I;CACNA1F;SLC34A2;RYR2;TRPV6;CACNB3;CACNA1G;PKD2L1;CATSPER1;CACNA1S;TRPV5;CACNA1E;RYR3 GO:0007409| axonogenesis S100B;S100A6;CREB1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound CASR;UGT1A1 GO:0055085| transmembrane transport TRPV6;TRPV5;CACNA1S;CATSPER1;CACNA1G;CACNA1E;RYR3;CACNA1I;ABCB1;CACNA1A;SLC34A2;CACNA1F;RYR2;SLC20A1;CACNA1H;SLCO1A2;CALM1;SLC20A2;SLC34A3;SLC8A1;CACNA1D;CACNA1C;RYR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;CIB1 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process NUCB1;SLC34A1;CALB1;ALB;SLC34A2 GO:0002576| platelet degranulation CALM1;SPARC;ALB GO:0043065| positive regulation of apoptotic process CREB1;S100B GO:0007626| locomotory behavior OPRK1;CALB1;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;CIB1;TPT1;RGN GO:0045087| innate immune response TLR4;S100B GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CALR GO:1990090| CIB1;CREB1 GO:0042981| regulation of apoptotic process ESR1;TPT1;CALR;CREB1 GO:0042060| wound healing SPARC;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;SPARC;UGT1A1;TLR4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0097190| apoptotic signaling pathway PDCD6;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;CASR;OPRK1 GO:0045471| response to ethanol SPARC;OPRM1;OPRK1;UGT1A1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;S100A13;S100B;TLR4 GO:0051481| reduction of cytosolic calcium ion concentration RYR3;OPRM1;SLC8A1 GO:0001889| liver development UGT1A1;RGN GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;CIB1 GO:0016032| viral reproduction SLC20A2;CREB1 GO:0051924| regulation of calcium ion transport SLC8A1;CASR;SRI;OPRD1 GO:0007268| synaptic transmission CACNA1E;CACNA1G;CACNB3;OPRK1;CACNB1;NRXN1;OPRD1;OPRM1;CACNB2;CACNB4 GO:0042493| response to drug SLC34A1;SLC8A1;CALR;CREB1;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;CALR;ESR1 GO:0043687| post-translational protein modification NUCB1;ALB 10385:[DB01183 DB08102] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport ABCB1;TTR 10386:[DB01183 DB07020] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways GO:0042752| regulation of circadian rhythm CREB1;MAPK9 GO:0043065| positive regulation of apoptotic process CREB1;MAPK9 GO:0048511| rhythmic process CREB1;MAPK9 GO:0010628| positive regulation of gene expression TLR4;MAPK9 GO:0006468| protein phosphorylation CREB1;MAPK9 10387:[DB01183 DB05739] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways GO:0042981| regulation of apoptotic process ESR1;AGTR2;CREB1 GO:0050727| regulation of inflammatory response TLR4;ESR1;AGTR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;AGTR1;OPRK1 GO:0051000| positive regulation of nitric-oxide synthase activity AGTR2;ESR1 GO:0006954| inflammatory response TLR4;AGTR2 GO:0045893| positive regulation of transcription, DNA-dependent AGTR2;CREB1;ESR1 GO:0007165| signal transduction OPRK1;AGTR2;CREB1;TLR4;AGTR1;ESR1;OPRM1;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;AGTR2 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;ESR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway AGTR1;OPRD1;OPRM1;OPRK1;AGTR2 GO:0050729| positive regulation of inflammatory response TLR4;AGTR1 10388:[DB01183 DB09308] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09308|Solithromycin CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 10389:[DB01183 DB08927] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08927|Amperozide HTR2A common genes common pathways GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2A;ESR1;OPRD1;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;HTR2A GO:0016032| viral reproduction CREB1;HTR2A GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1;HTR2A GO:0042493| response to drug ABCB1;CREB1;UGT1A1;HTR2A GO:0007165| signal transduction OPRM1;OPRD1;ESR1;HTR2A;OPRK1;CREB1;TLR4 GO:0007610| behavior HTR2A;OPRK1 GO:0007613| memory CREB1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1 GO:0007568| aging HTR2A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRD1;OPRM1;OPRK1 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;TLR4 10390:[DB01183 DB05966] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05966|TAS-108 ESR1;ESR2 common genes ESR1 common pathways GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRK1;ESR2;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;ESR2 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;ESR2 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 10391:[DB01183 DB04200] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04200|Matairesinol DHRS4L2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DHRS4L2 10392:[DB01183 DB08263] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08263|N-(carboxycarbonyl)-D-phenylalanine HIF1AN common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;CREB1;HIF1AN GO:0006355| regulation of transcription, DNA-dependent HIF1AN;CREB1;ESR1 GO:0055114| oxidation-reduction process CYP2C8;HIF1AN;CYP3A4 10393:[DB01183 DB05266] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0042493| response to drug CREB1;PDE3A;UGT1A1;ABCB1 GO:0032729| positive regulation of interferon-gamma production PDE4D;PDE4B;TLR4 GO:0006629| lipid metabolic process PDE3A;CYP3A4 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PDE3A GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PDE4B;PDE4D GO:0007568| aging CREB1;PDE4D GO:0007186| G-protein coupled receptor signaling pathway PDE4C;PDE4B;OPRK1;PDE3A;OPRM1;PDE4A;OPRD1;PDE4D GO:0007165| signal transduction PDE4B;PDE4C;OPRK1;PDE3A;CREB1;TLR4;OPRM1;PDE4A;OPRD1;PDE4D;ESR1 10394:[DB01183 DB08487] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08487|3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways 10395:[DB01183 DB13757] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13757|Epanolol CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 10396:[DB01183 DB07306] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways GO:0001666| response to hypoxia NOS2;CREB1 GO:0010629| negative regulation of gene expression CREB1;NOS2;ESR1;OPRD1 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0009617| response to bacterium TLR4;NOS2 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;NOS2 GO:0007623| circadian rhythm NOS2;CREB1 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0071222| cellular response to lipopolysaccharide TLR4;NOS2;OPRK1 10397:[DB01183 DB12319] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12319|Benzbromarone CYP2C9;CYP2C19;CYP2C19;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0006810| transport ABCB11;ABCB1 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1B1;SLCO1A2 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8;CYP2C9;UGT1A1 GO:0097267| CYP2C19;CYP2C8;CYP2C9 GO:0015711| organic anion transport SLCO1B1;SLCO1A2 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;ABCB11 GO:0006811| ion transport SLCO1A2;SLCO1B1;SLCO2B1 GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;SLCO1A2;SLCO2B1;ALB 10398:[DB01183 DB05488] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0007409| axonogenesis TOP2B;CREB1 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP1A2;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;CYP1A2;OPRM1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 10399:[DB01183 DB03577] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways GO:0051930| regulation of sensory perception of pain OPRK1;ACPP;OPRM1;OPRD1 10400:[DB01183 DB06525] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06525|Ganstigmine ACHE common genes common pathways 10401:[DB01183 DB00927] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CES1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0008542| visual learning CREB1;HRH2 GO:0006955| immune response HRH2;OPRD1;OPRK1;TLR4 GO:0007613| memory HRH2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;HRH2 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;ALB GO:0015711| organic anion transport SLC22A2;SLCO1A2 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19;UGT1A1 GO:0097267| CYP2C8;CYP2C19 GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;HRH2;OPRM1;OPRD1 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1;SLC22A2 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0006811| ion transport SLCO1A2;SLC22A8;SLC22A2 GO:0009636| response to toxin SLC22A8;CES1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;HRH2 10402:[DB01183 DB09006] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0001666| response to hypoxia CREB1;PPARA GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1;PPARD GO:0010033| response to organic substance PPARD;CREB1;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0014823| response to activity PPARD;CREB1 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0048511| rhythmic process PPARA;PPARG;CREB1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;PPARG;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0030154| cell differentiation CREB1;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042752| regulation of circadian rhythm CREB1;PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;PPARA;ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARA;PPARD;PPARG;CREB1 GO:0042493| response to drug ABCB1;UGT1A1;PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;ESR1;CREB1;PPARG GO:1901215| CREB1;PPARA GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0071222| cellular response to lipopolysaccharide PPARD;OPRK1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CREB1;TLR4;PPARA;ESR1 GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4;PPARD GO:0042594| response to starvation UGT1A1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PPARD;PPARA;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;PPARD;ESR1 GO:0042060| wound healing PPARA;PPARD;OPRM1 GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARD;PPARA;ESR1 GO:0006351| transcription, DNA-dependent CREB1;PPARG;ESR1;PPARA;PPARD GO:0097190| apoptotic signaling pathway TLR4;PPARD 10403:[DB01183 DB00979] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;CHRM1;OPRD1;OPRM1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007186| G-protein coupled receptor signaling pathway CHRM1;OPRD1;OPRM1;OPRK1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0042493| response to drug CREB1;UGT1A1;BCHE;ABCB1 10404:[DB01183 DB07577] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug UGT1A1;TYMS;CREB1;ABCB1 GO:0045471| response to ethanol UGT1A1;TYMS;OPRK1;OPRM1 GO:0007623| circadian rhythm CREB1;TYMS GO:0009636| response to toxin CES1;TYMS GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0007568| aging TYMS;CREB1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 10405:[DB01183 DB07489] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07489|4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium CSNK1G3 common genes common pathways GO:0006468| protein phosphorylation CSNK1G3;CREB1 GO:0007165| signal transduction CSNK1G3;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 10406:[DB01183 DB02811] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02811|Diethylphosphono Group BCHE;fbpC;BCHE common genes common pathways GO:0042493| response to drug ABCB1;CREB1;BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE 10407:[DB01183 DB04847] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04847|Roxadustat EGLN1;EGLN2;EGLN3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;EGLN1;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway EGLN2;ESR1 GO:0055114| oxidation-reduction process EGLN2;EGLN1;CYP2C8;EGLN3;CYP3A4 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity EGLN1;ESR1 GO:0001666| response to hypoxia CREB1;EGLN2;EGLN1;EGLN3 10408:[DB01183 DB09369] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09369|Polyestradiol phosphate ESR1 common genes ESR1 common pathways GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0002064| epithelial cell development ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 10409:[DB01183 DB08734] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0007623| circadian rhythm TYMS;CREB1 GO:0045471| response to ethanol OPRK1;TYMS;UGT1A1;OPRM1 GO:0042493| response to drug UGT1A1;TYMS;CREB1;ABCB1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0007568| aging TYMS;CREB1 GO:0009636| response to toxin CES1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS 10410:[DB01183 DB09116] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0045471| response to ethanol CAT;OPRM1;OPRK1;UGT1A1 GO:0043066| negative regulation of apoptotic process CAT;ALB GO:0008152| metabolic process CES1;UGT1A1;ALDH3B2 GO:0009314| response to radiation OPRM1;CAT;OPRK1 GO:0006629| lipid metabolic process CYP3A4;ALDH3B2 GO:0042493| response to drug CAT;ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CAT;ALDH3B2;CYP2C8 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TLR4 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;CAT GO:0032355| response to estradiol stimulus CAT;ESR1 GO:0007568| aging CREB1;CAT GO:0098869| CAT;ALB GO:0009636| response to toxin CES1;CAT GO:0032868| response to insulin stimulus OPRK1;CAT GO:0001666| response to hypoxia CAT;CREB1 GO:0014823| response to activity CREB1;CAT 10411:[DB01183 DB09347] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09347|Acetrizoic acid ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 10412:[DB01183 DB05029] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05029|Lancovutide PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;CYP3A4 GO:0008152| metabolic process CES1;PLA2G4A;UGT1A1 10413:[DB01183 DB13520] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13520|Metergoline SCN2A common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCB1;SCN2A GO:0006811| ion transport SLCO1A2;SCN2A 10414:[DB01183 DB08369] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2B6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2B6;UGT1A1;CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2B6;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2B6 10415:[DB01183 DB08348] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08348|N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE EEF2;PARP3;PARP15 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PARP15 GO:0006351| transcription, DNA-dependent ESR1;PARP15;CREB1 GO:0045471| response to ethanol OPRM1;EEF2;UGT1A1;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP15;CREB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;EEF2 GO:0007568| aging CREB1;EEF2 GO:0032355| response to estradiol stimulus EEF2;ESR1 10416:[DB01183 DB05876] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05876|PDE4 PDE4A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;PDE4A;OPRD1;OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;PDE4A;ESR1;OPRK1;CREB1;TLR4 10417:[DB01183 DB06441] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06441|Cangrelor P2RY12 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;P2RY12 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;P2RY12;OPRM1;OPRD1 GO:0070588| calcium ion transmembrane transport P2RY12;OPRM1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;P2RY12 GO:0043491| protein kinase B signaling cascade CREB1;P2RY12 GO:0051924| regulation of calcium ion transport P2RY12;OPRD1 10418:[DB01183 DB02431] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways GO:0008152| metabolic process UCK2;UGT1A1;CES1 10419:[DB01183 DB00601] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00601|Linezolid MAOA;MAOB common genes common pathways GO:0042493| response to drug MAOB;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process MAOB;CYP2C8;CYP3A4;MAOA GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;MAOB GO:0045471| response to ethanol MAOB;UGT1A1;OPRK1;OPRM1 GO:0009636| response to toxin MAOB;CES1 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 10420:[DB01183 DB09059] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0042711| maternal behavior AVPR1A;OXTR;OPRK1 GO:0032609| interferon-gamma production TLR4;AVPR2 GO:0007595| lactation CREB1;OXTR GO:0042493| response to drug ABCB1;UGT1A1;CREB1;OXTR GO:0010628| positive regulation of gene expression AVPR2;TLR4 GO:0010033| response to organic substance CREB1;UGT1A1;AVPR1A GO:0014070| response to organic cyclic compound UGT1A1;OXTR GO:0042755| eating behavior OXTR;OPRM1;OPRD1;OPRK1 GO:0042220| response to cocaine OPRM1;OXTR;OPRK1 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;AVPR2 GO:0032870| cellular response to hormone stimulus AVPR2;AVPR1B;UGT1A1;OXTR;AVPR1A GO:0044849| OPRM1;OXTR;OPRK1 GO:0007165| signal transduction TLR4;CREB1;AVPR1B;OPRK1;AVPR2;OXTR;ESR1;AVPR1A;OPRD1;OPRM1 GO:0048545| response to steroid hormone stimulus OXTR;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway AVPR1A;OXTR;OPRM1;OPRD1;AVPR1B;OPRK1;AVPR2 GO:0032355| response to estradiol stimulus ESR1;OXTR GO:0007204| elevation of cytosolic calcium ion concentration AVPR1B;OPRM1;OXTR;AVPR1A;ESR1 GO:0007613| memory CREB1;OXTR 10421:[DB01183 DB07902] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07902|TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE METAP1 common genes common pathways 10422:[DB01183 DB08805] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08805|Metiamide HRH2 common genes common pathways GO:0006955| immune response OPRK1;TLR4;OPRD1;HRH2 GO:0008542| visual learning CREB1;HRH2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;HRH2 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;HRH2;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;HRH2 GO:0007613| memory HRH2;CREB1 10423:[DB01183 DB01454] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0019233| sensory perception of pain OPRM1;OPRD1;HTR2A;OPRK1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HTR2B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TLR4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1;HTR2B;HTR2C;OPRK1 GO:0045471| response to ethanol UGT1A1;OPRK1;SLC6A3;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2D6 GO:0007626| locomotory behavior OPRM1;SLC18A2;HTR2C;SLC6A3;OPRK1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;SLC18A2;SLC6A2;OPRK1;HTR2C GO:0042493| response to drug ABCB1;HTR2C;HTR2B;SLC6A3;UGT1A1;SLC6A2;CREB1;SLC6A4;HTR2A GO:0035094| response to nicotine SLC6A3;CREB1 GO:0007595| lactation SLC6A3;CREB1 GO:0016032| viral reproduction HTR2A;CREB1 GO:0006810| transport ABCB1;SLC6A2 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging SLC6A3;CREB1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory HTR2A;SLC6A4;CREB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;HTR2A;OPRK1;HTR2B;HTR2C GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0007165| signal transduction ESR1;HTR2A;OPRM1;OPRD1;CREB1;TLR4;HTR2C;HTR2B;OPRK1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0007610| behavior HTR2A;HTR2C;HTR2B;OPRK1 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0042220| response to cocaine SLC6A3;OPRK1;OPRM1 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLC18A2;SLCO1A2;SLC6A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;HTR2C;HTR2B;HTR2A;OPRM1 GO:0009636| response to toxin SLC6A4;SLC18A2;CES1 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0010033| response to organic substance SLC6A4;CREB1;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;CREB1 10424:[DB01183 DB05459] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05459|Briakinumab IL12B;IL23A common genes common pathways GO:0010033| response to organic substance UGT1A1;CREB1;IL12B GO:0002376| immune system process TLR4;IL23A GO:0050729| positive regulation of inflammatory response IL12B;TLR4;IL23A GO:0032735| positive regulation of interleukin-12 production TLR4;IL12B;IL23A GO:0032700| negative regulation of interleukin-17 production IL12B;TLR4 GO:0006955| immune response OPRD1;IL23A;TLR4;OPRK1 GO:0006954| inflammatory response IL23A;TLR4 GO:0032609| interferon-gamma production IL12B;TLR4 GO:0032760| positive regulation of tumor necrosis factor production TLR4;IL12B;IL23A GO:0051607| defense response to virus IL23A;OPRK1;IL12B GO:0042346| positive regulation of NF-kappaB import into nucleus IL12B;TLR4;IL23A GO:0045672| positive regulation of osteoclast differentiation IL23A;IL12B;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;IL23A GO:0050829| defense response to Gram-negative bacterium IL23A;IL12B;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;IL12B GO:0042088| T-helper 1 type immune response TLR4;IL12B GO:0032733| positive regulation of interleukin-10 production IL23A;IL12B;TLR4 GO:0045087| innate immune response IL23A;TLR4 GO:0050671| positive regulation of lymphocyte proliferation TLR4;IL12B GO:0032729| positive regulation of interferon-gamma production IL12B;TLR4;IL23A GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1;IL12B 10425:[DB01183 DB08072] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08072|4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE PLAU common genes common pathways GO:0001666| response to hypoxia PLAU;CREB1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;PLAU;OPRK1;TLR4;CREB1 10426:[DB01183 DB00914] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0032496| response to lipopolysaccharide OPRM1;KCNJ8;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0006351| transcription, DNA-dependent CREB1;PRKAA1;ESR1 GO:0006695| cholesterol biosynthetic process PRKAA1;CES1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0043066| negative regulation of apoptotic process PRKAA1;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2D6 GO:0071361| cellular response to ethanol PRKAA1;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PRKAA1 GO:2000505| regulation of energy homeostasis OPRK1;PRKAA1 GO:0051607| defense response to virus KCNJ8;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PRKAA1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0042752| regulation of circadian rhythm PRKAA1;CREB1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;PRKAA1;UGT1A1;CYP3A4 GO:0071456| cellular response to hypoxia PRKAA1;OPRD1 GO:0006468| protein phosphorylation PRKAA1;CREB1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0015711| organic anion transport SLC22A2;SLC22A1;SLCO1A2 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;PRKAA1;CREB1;TLR4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0006811| ion transport KCNJ8;SLCO1A2;SLC22A2;SLC22A1 GO:0000187| activation of MAPK activity PRKAA1;TLR4 GO:0055085| transmembrane transport SLCO1A2;SLC22A2;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0010628| positive regulation of gene expression PRKAA1;TLR4 GO:0001666| response to hypoxia CREB1;PRKAA1 GO:0014823| response to activity PRKAA1;CREB1 GO:0048511| rhythmic process PRKAA1;CREB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 10427:[DB01183 DB07221] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;GGPS1 10428:[DB01183 DB01956] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0001889| liver development UGT1A1;BAAT GO:0045471| response to ethanol GRIN2B;OPRM1;OPRK1;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRA2;OPRM1;GLRA3;GRIN2B GO:0071294| cellular response to zinc ion CREB1;GLRA1;GLRA2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;GABBR1 GO:0071361| cellular response to ethanol GLRA2;UGT1A1;GLRA1 GO:0006629| lipid metabolic process CYP3A4;BAAT GO:0007586| digestion UGT1A1;SLC15A1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRA1;GLRA2;OPRM1;OPRD1;GLRA3 GO:1901215| CREB1;GABRB2;GABRB3 GO:0007268| synaptic transmission GRIN2B;GLRA3;OPRM1;GABRG2;OPRD1;GLRA2;GABRB2;GABRD;GLRA1;GABRG1;GABRA5;OPRK1 GO:0042493| response to drug GABRG3;ABCB1;UGT1A1;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;GABBR1;OPRM1;OPRD1 GO:0006810| transport ABCB1;GABRA3;GABRA5;GABRD;GABRB2;SLC15A1;GABRB3;SLC6A6;GABRG2;GABRB1;GRIN2B;GABRA4;GABRA6;GABRA1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;GABBR1;OPRD1;OPRK1 GO:0007165| signal transduction TLR4;GABRP;GABRD;CREB1;GABRA5;OPRK1;ESR1;GABRA6;GABRQ;GABRB1;OPRD1;GABBR1;OPRM1;GABRE;GABRB3 GO:0031100| organ regeneration UGT1A1;BAAT GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO1A2;SLC36A1 GO:0009636| response to toxin CES1;GABRB1 GO:0006811| ion transport GABRA2;GABRD;GABRB2;GABRP;SLC15A1;GLRA1;GABRG1;GABRA5;GABRA3;GLRA2;GABRB3;GABRG3;SLC36A1;GABRA4;GABRA6;GRIN2B;GABRA1;GLRA3;GABRE;GABRB1;GABRG2;SLCO1A2;GABRQ 10429:[DB01183 DB01780] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01780|Fusicoccin YWHAE common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;YWHAE GO:0016032| viral reproduction CREB1;YWHAE 10430:[DB01183 DB04465] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways GO:0030154| cell differentiation CREB1;LGALS3 GO:0002376| immune system process TLR4;LGALS3 GO:0030855| epithelial cell differentiation CES1;LGALS3 GO:0045087| innate immune response LGALS3;TLR4 10431:[DB01183 DB01717] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways 10432:[DB01183 DB07181] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10433:[DB01183 DB12887] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12887|Tazemetostat EZH2 common genes common pathways GO:0032355| response to estradiol stimulus EZH2;ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity EZH2;ESR1 GO:0048511| rhythmic process CREB1;EZH2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;EZH2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;EZH2 GO:0006351| transcription, DNA-dependent EZH2;ESR1;CREB1 GO:0071168| protein localization to chromatin EZH2;ESR1 GO:0042752| regulation of circadian rhythm EZH2;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;EZH2;CREB1 GO:0010629| negative regulation of gene expression ESR1;EZH2;OPRD1;CREB1 10434:[DB01183 DB11831] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11831|Dinitrochlorobenzene MGMT;GSTP1 common genes common pathways GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin GSTP1;CES1;MGMT GO:0014070| response to organic cyclic compound UGT1A1;MGMT GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0098869| ALB;GSTP1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;MGMT GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;GSTP1 GO:0045471| response to ethanol OPRK1;GSTP1;UGT1A1;MGMT;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;OPRK1 GO:0006805| xenobiotic metabolic process CYP2C8;GSTP1;CES1;CYP3A4 GO:0008152| metabolic process GSTP1;UGT1A1;CES1 GO:0043066| negative regulation of apoptotic process MGMT;GSTP1;ALB 10435:[DB01183 DB02628] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02628|1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide XIAP common genes common pathways GO:0050727| regulation of inflammatory response XIAP;ESR1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;XIAP 10436:[DB01183 DB05744] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways GO:0051930| regulation of sensory perception of pain IL10;OPRK1;OPRM1;OPRD1 GO:0000187| activation of MAPK activity TNF;TLR4 GO:0044267| cellular protein metabolic process IL6;ALB GO:0032868| response to insulin stimulus IL10;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;TNF;OPRM1 GO:0010628| positive regulation of gene expression IL6;TLR4;TNF;CRP GO:0010033| response to organic substance TNF;IL10;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;IL6;IL10 GO:0014823| response to activity CREB1;IL10 GO:0051384| response to glucocorticoid stimulus TNF;IL10;UGT1A1;IL6 GO:0007568| aging CREB1;IL10 GO:0071392| cellular response to estradiol stimulus UGT1A1;IL10;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TLR4;OPRM1;ESR1 GO:0032755| positive regulation of interleukin-6 production IL6;TLR4;TNF GO:0035729| cellular response to hepatocyte growth factor stimulus CREB1;IL10 GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TLR4;TNF;IL10 GO:0032720| negative regulation of tumor necrosis factor production IL10;TLR4 GO:0032689| negative regulation of interferon-gamma production TLR4;IL10 GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0043032| positive regulation of macrophage activation IL10;TLR4 GO:0032722| positive regulation of chemokine production TLR4;TNF;IL6 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;IL10 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;TNF;IL6 GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0045893| positive regulation of transcription, DNA-dependent ESR1;TNF;CREB1;IL10;IL6 GO:0010629| negative regulation of gene expression CREB1;TNF;OPRD1;ESR1 GO:0042493| response to drug IL10;CREB1;UGT1A1;ABCB1 GO:0051607| defense response to virus OPRK1;IL6 GO:0043687| post-translational protein modification IL6;ALB GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0042742| defense response to bacterium IL10;TLR4;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF;IL10;IL6 GO:0006955| immune response OPRD1;IL10;TLR4;TNF;IL6;OPRK1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IL6;TNF;TLR4 GO:0006954| inflammatory response CRP;IL10;TNF;TLR4;IL6 GO:0006953| acute-phase response IL6;UGT1A1;CRP GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0032496| response to lipopolysaccharide OPRM1;IL10;TLR4;UGT1A1 GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0045348| positive regulation of MHC class II biosynthetic process IL10;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TNF GO:0043066| negative regulation of apoptotic process ALB;IL6;IL10 GO:0050727| regulation of inflammatory response ESR1;TNF;TLR4 GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0043065| positive regulation of apoptotic process CREB1;TNF;IL6 GO:0050829| defense response to Gram-negative bacterium IL6;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;TNF;IL10;IL6;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IL6;CREB1;IL10;TLR4;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 10437:[DB01183 DB08078] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0042060| wound healing PPARD;OPRM1 GO:0006351| transcription, DNA-dependent ESR1;PPARD;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARD GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0071222| cellular response to lipopolysaccharide PPARD;TLR4;OPRK1 GO:0006629| lipid metabolic process PPARD;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARD;CREB1 GO:0006355| regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0030154| cell differentiation CREB1;PPARD GO:0010628| positive regulation of gene expression PPARD;TLR4 GO:0045600| positive regulation of fat cell differentiation PPARD;CREB1 GO:0014823| response to activity PPARD;CREB1 GO:0010033| response to organic substance UGT1A1;CREB1;PPARD 10438:[DB01183 DB05867] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 10439:[DB01183 DB12228] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CALCRL GO:0045671| negative regulation of osteoclast differentiation TLR4;CALCA GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CALCRL;CREB1;CALCB;OPRK1 GO:0032757| positive regulation of interleukin-8 production TLR4;CALCA GO:0006468| protein phosphorylation CREB1;CALCA GO:0007186| G-protein coupled receptor signaling pathway CALCB;OPRK1;CALCRL;CALCA;OPRM1;OPRD1 GO:0045087| innate immune response CALCA;TLR4 GO:0050829| defense response to Gram-negative bacterium CALCA;TLR4 10440:[DB01183 DB00489] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0016579| protein deubiquitination ADRB2;ESR1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:1904646| ADRB2;TLR4 GO:0055085| transmembrane transport ABCB1;KCNH2;SLCO1A2 GO:0006811| ion transport SLCO1A2;KCNH2 GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;ADRB2;ADRB1;OPRK1;CREB1;TLR4 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:1901381| OPRK1;KCNH2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB1;ADRB2;OPRM1;OPRD1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 10441:[DB01183 DB05003] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05003|Imexon RRM2;RRM1 common genes common pathways GO:0008584| male gonad development ESR1;RRM1 GO:0055114| oxidation-reduction process RRM1;CYP2C8;RRM2;CYP3A4 GO:0008152| metabolic process UGT1A1;RRM1;CES1 10442:[DB01183 DB03667] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C8 GO:0006954| inflammatory response PTGS1;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0098869| PTGS1;ALB 10443:[DB01183 DB02562] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02562|Quinonoid 7,8-Tetrahydrobiopterin PAH common genes common pathways GO:0055114| oxidation-reduction process PAH;CYP2C8;CYP3A4 GO:0008152| metabolic process PAH;UGT1A1;CES1 10444:[DB01183 DB00209] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRM1;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;CHRM1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 10445:[DB01183 DB01963] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways GO:0007586| digestion UGT1A1;CTRB1 10446:[DB01183 DB03359] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways 10447:[DB01183 DB04978] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04978|SP1049C TOP2A common genes common pathways GO:0048511| rhythmic process TOP2A;CREB1 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;TOP2A;CREB1 10448:[DB01183 DB05205] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05205|CX157 MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8 10449:[DB01183 DB04090] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04090|RH-1 NQO1 common genes common pathways GO:0032355| response to estradiol stimulus NQO1;ESR1 GO:0007568| aging NQO1;CREB1 GO:0007584| response to nutrient UGT1A1;NQO1 GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0009636| response to toxin NQO1;CES1 GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;NQO1 GO:0045471| response to ethanol OPRM1;UGT1A1;NQO1;OPRK1 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NQO1 10450:[DB01183 DB04983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04983|Denufosol P2RY2 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;P2RY2;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;P2RY2;OPRK1 GO:0007165| signal transduction P2RY2;ESR1;OPRM1;OPRD1;OPRK1;CREB1;TLR4 10451:[DB01183 DB04271] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction ESR1;PDE4D;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0007568| aging CREB1;PDE4D GO:0007186| G-protein coupled receptor signaling pathway PDE4D;OPRD1;OPRM1;OPRK1 GO:0071222| cellular response to lipopolysaccharide PDE4D;OPRK1;TLR4 GO:0032729| positive regulation of interferon-gamma production TLR4;PDE4D 10452:[DB01183 DB11714] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11714|Durvalumab CD274;CD80 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CREB1 GO:0006955| immune response OPRK1;CD274;TLR4;OPRD1 GO:0016032| viral reproduction CREB1;CD80 GO:0007165| signal transduction TLR4;CD274;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0032689| negative regulation of interferon-gamma production CD274;TLR4 10453:[DB01183 DB03753] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C8 GO:0006954| inflammatory response TLR4;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 10454:[DB01183 DB14025] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0097267| CYP1A2;CYP2C19;CYP2C8;CYP2C9 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2C9;UGT1A1;CYP2C19;CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8;CYP2C19;CYP2D6;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP1A2 10455:[DB01183 DB14634] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14634|Fluprednidene acetate CYP3A4 common genes CYP3A4 common pathways GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 10456:[DB01183 DB08455] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08455|Ro 12-7310 CRABP2 common genes common pathways GO:0042573| retinoic acid metabolic process CRABP2;UGT1A1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CRABP2;CREB1;TLR4;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CRABP2;CREB1 10457:[DB01183 DB04690] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes ABCB1;ALB common pathways GO:0042493| response to drug TOP1;CREB1;UGT1A1;ABCG2;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0043687| post-translational protein modification ALB GO:0099040| ABCB1 GO:0016032| viral reproduction TOP1;CREB1 GO:1901529| ABCB1 GO:0007623| circadian rhythm TOP1;CREB1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0048511| rhythmic process CREB1;TOP1 GO:0072089| stem cell proliferation ABCB1 GO:0051659| maintenance of mitochondrion location ALB GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0006338| chromatin remodeling ESR1;TOP1 GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB 10458:[DB01183 DB03499] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03499|Malate Ion fumC;glcB;ME2;CS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ME2;CYP2C8 GO:0008152| metabolic process CES1;ME2;UGT1A1 10459:[DB01183 DB02486] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways GO:0008152| metabolic process CES1;GSTA1;UGT1A1 GO:0098869| ALB;GSTA1 GO:0030855| epithelial cell differentiation GSTA1;CES1 10460:[DB01183 DB06543] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06543|Astaxanthin NFKBIA common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKBIA;TLR4 GO:0050729| positive regulation of inflammatory response NFKBIA;TLR4 GO:0016579| protein deubiquitination ESR1;NFKBIA GO:0034142| toll-like receptor 4 signaling pathway NFKBIA;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NFKBIA;ESR1 GO:0043066| negative regulation of apoptotic process NFKBIA;ALB GO:0031663| lipopolysaccharide-mediated signaling pathway NFKBIA;TLR4 GO:0000060| protein import into nucleus, translocation OPRD1;NFKBIA GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;NFKBIA;OPRM1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;NFKBIA GO:0016032| viral reproduction NFKBIA;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NFKBIA;ESR1 10461:[DB01183 DB06994] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10462:[DB01183 DB00154] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0098869| ALB;PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;PTGS2;OPRM1;ESR1 GO:0007613| memory PTGS2;CREB1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007568| aging CREB1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1;CREB1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;FABP7 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response TLR4;ESR1;PTGS2 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;PTGS1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0019233| sensory perception of pain OPRK1;OPRM1;PTGS2;OPRD1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;UGT1A1;TLR4 GO:0006954| inflammatory response TLR4;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4;PTGS2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;PTGS2 10463:[DB01183 DB00221] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ADRB2;CREB1;TLR4 GO:0016579| protein deubiquitination ADRB2;ESR1 GO:1904646| ADRB2;TLR4 GO:0007165| signal transduction OPRK1;ADRB1;TLR4;CREB1;ADRB2;ESR1;OPRD1;OPRM1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;OPRD1;OPRM1;OPRK1;ADRB1 10464:[DB01183 DB05227] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05227|APD791 HTR2A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRD1;OPRM1;OPRK1 GO:0007568| aging HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1 GO:0007613| memory HTR2A;CREB1 GO:0007610| behavior HTR2A;OPRK1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;HTR2A;OPRM1;OPRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;HTR2A GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0019233| sensory perception of pain OPRM1;OPRD1;HTR2A;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1;OPRK1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;HTR2A GO:0042493| response to drug HTR2A;ABCB1;UGT1A1;CREB1 GO:0016032| viral reproduction CREB1;HTR2A 10465:[DB01183 DB08908] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0045084| positive regulation of interleukin-12 biosynthetic process TLR4;RELA GO:0032868| response to insulin stimulus RELA;OPRK1 GO:0014070| response to organic cyclic compound UGT1A1;RELA GO:0010033| response to organic substance RELA;CREB1;UGT1A1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity KEAP1;ESR1 GO:0016579| protein deubiquitination KEAP1;ESR1 GO:0007568| aging CREB1;RELA GO:0035729| cellular response to hepatocyte growth factor stimulus CREB1;RELA GO:0043687| post-translational protein modification KEAP1;ALB GO:0009617| response to bacterium RELA;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent RELA;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;RELA;KEAP1;CREB1 GO:0051607| defense response to virus OPRK1;RELA GO:0042493| response to drug ABCB1;CREB1;UGT1A1;RELA GO:0043278| response to morphine OPRM1;RELA;OPRK1 GO:0016032| viral reproduction CREB1;RELA GO:0006954| inflammatory response RELA;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;RELA GO:0001889| liver development RELA;UGT1A1 GO:0006351| transcription, DNA-dependent RELA;ESR1;CREB1;KEAP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;RELA GO:0071223| cellular response to lipoteichoic acid RELA;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;RELA;TLR4;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;RELA GO:0043066| negative regulation of apoptotic process RELA;ALB GO:0071222| cellular response to lipopolysaccharide RELA;TLR4;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RELA;ESR1;TLR4;CREB1 GO:0050727| regulation of inflammatory response ESR1;RELA;TLR4 10466:[DB01183 DB05104] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05104|Asimadoline OPRK1 common genes OPRK1 common pathways GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0032868| response to insulin stimulus OPRK1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:1901381| OPRK1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1 GO:1990708| OPRK1 GO:0044849| OPRM1;OPRK1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0007610| behavior OPRK1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0051607| defense response to virus OPRK1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:0042711| maternal behavior OPRK1 GO:0006955| immune response OPRK1;TLR4;OPRD1 GO:1903937| OPRK1 GO:0007600| sensory perception OPRK1;OPRM1 GO:0043278| response to morphine OPRM1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1 GO:0019233| sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0009314| response to radiation OPRK1;OPRM1 GO:0007218| neuropeptide signaling pathway OPRK1;OPRM1;OPRD1 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1 GO:0048148| behavioral response to cocaine OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:1903715| OPRK1 GO:1900745| OPRK1 10467:[DB01183 DB04297] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04297|7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide HDAC8;HDAC7 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC7;ESR1;HDAC8 GO:0006351| transcription, DNA-dependent ESR1;HDAC7;HDAC8;CREB1 GO:0010629| negative regulation of gene expression HDAC8;OPRD1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HDAC8;ESR1;HDAC7 10468:[DB01183 DB05013] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways GO:0007411| axon guidance PRKCA;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;PRKCA;TLR4 GO:0007165| signal transduction OPRK1;CREB1;TLR4;PRKCD;ESR1;OPRM1;OPRD1 GO:0050821| protein stabilization CREB1;PRKCD GO:0006468| protein phosphorylation PRKCA;CREB1;PRKCD GO:0042742| defense response to bacterium PRKCD;TLR4 GO:0097190| apoptotic signaling pathway PRKCA;TLR4 10469:[DB01183 DB04803] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04803|Verdoheme HMOX1 common genes common pathways GO:0042167| heme catabolic process HMOX1;UGT1A1 GO:0071456| cellular response to hypoxia OPRD1;HMOX1 GO:0001666| response to hypoxia HMOX1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HMOX1 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0043627| response to estrogen stimulus OPRK1;ESR1;HMOX1 GO:0043065| positive regulation of apoptotic process CREB1;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;TLR4 GO:0035094| response to nicotine HMOX1;CREB1 GO:0055114| oxidation-reduction process CYP3A4;HMOX1;CYP2C8 10470:[DB01183 DB05706] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways GO:0048511| rhythmic process TOP2A;CREB1 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;CREB1;TLR4;ESR1 10471:[DB01183 DB04487] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04487|N-Methylleucine CXCL10 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;CXCL10;OPRK1;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;CXCL10 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;CXCL10 GO:0006954| inflammatory response CXCL10;TLR4 GO:0006955| immune response OPRD1;CXCL10;TLR4;OPRK1 GO:0051607| defense response to virus OPRK1;CXCL10 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;CXCL10 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CXCL10;CREB1;TLR4 GO:0032496| response to lipopolysaccharide TLR4;CXCL10;UGT1A1;OPRM1 10472:[DB01183 DB08167] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08167|Methylthioninium ACHE common genes common pathways 10473:[DB01183 DB11584] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11584|Pipradrol DRD1;DRD5 common genes common pathways GO:0007613| memory CREB1;DRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD5;DRD1;OPRM1;OPRD1 GO:0014002| astrocyte development DRD1;TLR4 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;DRD5;DRD1;CREB1;TLR4;OPRK1 GO:0042220| response to cocaine OPRK1;DRD5;DRD1;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRM1;OPRD1 GO:0010628| positive regulation of gene expression TLR4;DRD1 GO:0042060| wound healing DRD5;OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;DRD5;OPRM1 GO:0048148| behavioral response to cocaine OPRK1;DRD1 GO:0007626| locomotory behavior OPRM1;DRD1;OPRK1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;DRD1 GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1;DRD5 GO:0008542| visual learning DRD1;CREB1 GO:0042711| maternal behavior OPRK1;DRD1 10474:[DB01183 DB08658] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08658|ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0042493| response to drug ABCB1;BCHE;UGT1A1;CREB1 10475:[DB01183 DB02498] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02498|Carba-Nicotinamide-Adenine-Dinucleotide PARP1 common genes common pathways GO:1904646| TLR4;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0006366| transcription from RNA polymerase II promoter PARP1;ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;PARP1;ESR1 GO:0006351| transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0071294| cellular response to zinc ion PARP1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PARP1 10476:[DB01183 DB02123] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes SLCO1A2 common pathways GO:0016032| viral reproduction CREB1;SLC10A1 GO:0015721| bile acid and bile salt transport ALB;SLC10A2;SLC10A1;ABCB11;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;ABCB11;ABCB1;SLC10A1;SLC10A2 GO:0006811| ion transport SLC10A2;SLC10A1;SLCO1A2 GO:0015711| organic anion transport SLCO1A2 GO:0006810| transport ABCB1;SLC10A2;SLC10A1;ABCB11 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 10477:[DB01183 DB05890] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05890|VEGF-AS VEGFA common genes common pathways GO:0001666| response to hypoxia CREB1;VEGFA GO:0010628| positive regulation of gene expression TLR4;VEGFA GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;VEGFA GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0030154| cell differentiation CREB1;VEGFA GO:0071456| cellular response to hypoxia VEGFA;OPRD1 GO:0007595| lactation CREB1;VEGFA GO:0010629| negative regulation of gene expression ESR1;VEGFA;OPRD1;CREB1 GO:0002576| platelet degranulation VEGFA;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;VEGFA;TLR4;CREB1 GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0060749| mammary gland alveolus development ESR1;VEGFA GO:1900745| VEGFA;OPRK1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA 10478:[DB01183 DB07779] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10479:[DB01183 DB12328] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12328|Cantharidin AHR common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CES1;AHR;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AHR;TLR4;CREB1 GO:0006351| transcription, DNA-dependent ESR1;AHR;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;AHR GO:0006355| regulation of transcription, DNA-dependent CREB1;AHR;ESR1 GO:0048511| rhythmic process CREB1;AHR GO:0006366| transcription from RNA polymerase II promoter AHR;CREB1;ESR1 GO:0009636| response to toxin AHR;CES1 10480:[DB01183 DB08043] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ABL1;OPRM1 GO:0002322| B cell proliferation involved in immune response ABL1;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1;OPRM1 GO:0006468| protein phosphorylation CREB1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ABL1;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;TLR4 GO:0043065| positive regulation of apoptotic process ABL1;CREB1 GO:0045087| innate immune response ABL1;TLR4 10481:[DB01183 DB00034] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00034|Interferon Alfa-2a, Recombinant IFNAR1;IFNAR2 common genes common pathways GO:0051607| defense response to virus OPRK1;IFNAR2 GO:0032496| response to lipopolysaccharide IFNAR1;OPRM1;UGT1A1;TLR4 10482:[DB01183 DB00817] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 10483:[DB01183 DB07623] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways GO:0017144| drug metabolic process CYP2A6;CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;UGT1A1;CYP2C8 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6 10484:[DB01183 DB07524] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07524|N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 GO:0006468| protein phosphorylation PIM1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 10485:[DB01183 DB07248] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PTK2 GO:0043066| negative regulation of apoptotic process PTK2;ALB GO:0045087| innate immune response TLR4;PTK2 GO:0007179| transforming growth factor beta receptor signaling pathway PTK2;CREB1 GO:0007411| axon guidance PTK2;CREB1 GO:0006468| protein phosphorylation CREB1;PTK2 10486:[DB01183 DB03951] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 10487:[DB01183 DB05319] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05319|Oportuzumab monatox EPCAM common genes common pathways GO:0048863| stem cell differentiation ESR1;EPCAM GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;EPCAM;CREB1;TLR4 10488:[DB01183 DB09076] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;CHRM4;OPRK1;OPRM1;CHRM5;OPRD1;CHRM1;CHRM2 GO:0007165| signal transduction OPRM1;CHRM5;OPRD1;ESR1;CHRM1;CHRM2;CHRM3;CREB1;TLR4;CHRM4;OPRK1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRM1;OPRD1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0007586| digestion CHRM3;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CES1;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 10489:[DB01183 DB08804] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0007165| signal transduction ESR1;OPRD1;OPRM1;AR;TLR4;CREB1;OPRK1 GO:0006810| transport ABCB1;AR GO:0008584| male gonad development ESR1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0030879| mammary gland development CYP19A1;CREB1 GO:0009636| response to toxin MAOB;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;TLR4;CREB1 GO:0060065| uterus development CYP19A1;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0032496| response to lipopolysaccharide OPRM1;MAOB;UGT1A1;TLR4 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045471| response to ethanol OPRM1;UGT1A1;MAOB;OPRK1 GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0042493| response to drug UGT1A1;MAOB;CREB1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP19A1;MAOB;CYP2C8 10490:[DB01183 DB08516] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08516|(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] MAOB common genes common pathways GO:0042493| response to drug CREB1;MAOB;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MAOB;OPRM1 GO:0045471| response to ethanol OPRK1;UGT1A1;MAOB;OPRM1 GO:0009636| response to toxin CES1;MAOB GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 10491:[DB01183 DB01342] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01342|Forasartan AGTR1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;OPRM1;ESR1 GO:0050729| positive regulation of inflammatory response AGTR1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;AGTR1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;AGTR1;ESR1;OPRM1;OPRD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1;AGTR1 GO:0050727| regulation of inflammatory response TLR4;AGTR1;ESR1 10492:[DB01183 DB03553] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03553|Glutaric Acid ilvE;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0015711| organic anion transport SLC22A7;SLC22A11;SLCO1A2;SLC22A6 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1A2;SLC22A8;SLC22A11;SLC22A7 GO:0009636| response to toxin SLC22A8;CES1 GO:0006811| ion transport SLC22A8;SLCO1A2;SLC22A7;SLC22A11 GO:0055085| transmembrane transport SLC22A6;ABCB1;SLC22A8;SLCO1A2;SLC22A11;SLC22A7 10493:[DB01183 DB03796] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes ALB;CYP2C8 common pathways GO:0008285| negative regulation of cell proliferation OPRM1;FABP3 GO:0048511| rhythmic process CREB1;PPARA GO:0001666| response to hypoxia PPARA;CREB1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0032868| response to insulin stimulus PPARA;FABP3;OPRK1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002933| CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0097267| CYP2C8 GO:0007165| signal transduction RHO;TLR4;CREB1;OPRK1;OPRD1;OPRM1;LALBA;ESR1 GO:0098869| ALB GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0006898| receptor-mediated endocytosis ALB;PPT1 GO:0043069| negative regulation of programmed cell death ALB GO:0006468| protein phosphorylation RHO;CREB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0050729| positive regulation of inflammatory response FABP4;TLR4 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRK1;RHO;OPRD1;OPRM1 GO:0042752| regulation of circadian rhythm CREB1;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter HNF4G;PPARA;ESR1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042742| defense response to bacterium LALBA;TLR4 GO:1901215| PPARA;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARA;ESR1;SEC14L2 GO:0006355| regulation of transcription, DNA-dependent SEC14L2;PPARA;ESR1;HNF4G;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0007268| synaptic transmission OPRK1;OPRD1;PPT1;OPRM1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;FABP3 GO:0007586| digestion FABP2;UGT1A1 GO:0006629| lipid metabolic process PPARA;CYP3A4;FABP5 GO:0006082| organic acid metabolic process CYP2C8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;ESR1 GO:0043066| negative regulation of apoptotic process ALB;PPT1 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0050829| defense response to Gram-negative bacterium TLR4;LALBA GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;HNF4G;ESR1;PPARA GO:0050727| regulation of inflammatory response FABP4;ESR1;TLR4 GO:0002576| platelet degranulation ALB GO:0006351| transcription, DNA-dependent CREB1;HNF4G;SEC14L2;ESR1;PPARA GO:0043401| steroid hormone mediated signaling pathway HNF4G;ESR1;PPARA GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;HNF4G GO:0042060| wound healing OPRM1;PPARA 10494:[DB01183 DB07847] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07847|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE F10 common genes common pathways 10495:[DB01183 DB05187] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0001666| response to hypoxia PPARA;CREB1 GO:0045600| positive regulation of fat cell differentiation PPARD;CREB1;PPARG GO:0010033| response to organic substance PPARD;PPARG;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0014823| response to activity CREB1;PPARD GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0048511| rhythmic process PPARA;PPARG;CREB1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0030154| cell differentiation CREB1;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction OPRK1;TLR4;PPARG;CREB1;ESR1;OPRD1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARA;PPARD;CREB1;PPARG GO:0042493| response to drug UGT1A1;PPARG;CREB1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;PPARA;ESR1;PPARD GO:1901215| PPARA;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;PPARA;ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1;PPARA GO:0042060| wound healing PPARA;PPARD;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARA;ESR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;CREB1;PPARD;ESR1;PPARA GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;PPARA;ESR1 GO:0071222| cellular response to lipopolysaccharide PPARD;OPRK1;TLR4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process PPARA;CYP3A4;PPARD;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PPARD;ESR1;PPARA GO:0045087| innate immune response PPARG;TLR4 10496:[DB01183 DB05838] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05838|OPC-51803 AVPR2 common genes common pathways GO:0010628| positive regulation of gene expression AVPR2;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;AVPR2 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;AVPR2;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;AVPR2 GO:0032609| interferon-gamma production AVPR2;TLR4 10497:[DB01183 DB03107] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;SLCO1A2;ABCB1 10498:[DB01183 DB03729] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03729|2-Amino-5-Hydroxy-Benzimidazole PLAU common genes common pathways GO:0001666| response to hypoxia CREB1;PLAU GO:0007165| signal transduction CREB1;TLR4;PLAU;OPRK1;OPRM1;OPRD1;ESR1 10499:[DB01183 DB04454] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways GO:0060749| mammary gland alveolus development EGF;ESR1 GO:0002576| platelet degranulation EGF;ALB GO:0045893| positive regulation of transcription, DNA-dependent ESR1;EGF;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;EGF;OPRK1;CREB1;TLR4 GO:0010628| positive regulation of gene expression EGF;TLR4 GO:0000187| activation of MAPK activity TLR4;EGF 10500:[DB01183 DB00754] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00754|Ethotoin SCN5A;NR1I2 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NR1I2;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;NR1I2;CREB1;ESR1 GO:0006805| xenobiotic metabolic process NR1I2;CYP2C8;CES1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;NR1I2;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008202| steroid metabolic process NR1I2;UGT1A1;CYP2C8;CYP3A4 GO:0007165| signal transduction OPRK1;TLR4;NR1I2;CREB1;ESR1;OPRD1;OPRM1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SCN5A GO:0006811| ion transport SCN5A;SLCO1A2 GO:0010628| positive regulation of gene expression TLR4;NR1I2 10501:[DB01183 DB02705] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02705|6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction PLAU;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0001666| response to hypoxia CREB1;PLAU 10502:[DB01183 DB06080] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;ESR1 GO:0046330| positive regulation of JNK cascade FLT4;TLR4 GO:0043066| negative regulation of apoptotic process FLT4;KDR;ALB;CSF1R GO:0009314| response to radiation OPRM1;KIT;OPRK1 GO:0042981| regulation of apoptotic process CREB1;ESR1;FLT3 GO:0045087| innate immune response CSF1R;TLR4 GO:0010629| negative regulation of gene expression KDR;CREB1;OPRD1;ESR1 GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0016032| viral reproduction CREB1;KDR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;ESR1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;FLT3 GO:0006954| inflammatory response TLR4;CSF1R;KIT GO:0048863| stem cell differentiation ESR1;KIT GO:0008542| visual learning CREB1;KIT GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0030154| cell differentiation CREB1;KDR;FLT1;FLT3 GO:0006468| protein phosphorylation FLT3;FLT1;CSF1R;KIT;CREB1;FLT4;KDR GO:0010863| positive regulation of phospholipase C activity ESR1;FLT1;KIT GO:0002376| immune system process TLR4;CSF1R GO:0031100| organ regeneration FLT3;UGT1A1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1;CSF1R;KIT GO:0000187| activation of MAPK activity KIT;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade KDR;FLT4;TLR4;CSF1R;OPRM1 GO:0010628| positive regulation of gene expression TLR4;KIT GO:0008584| male gonad development KIT;ESR1 GO:0008285| negative regulation of cell proliferation CSF1R;OPRM1 GO:0007411| axon guidance CREB1;CSF1R 10503:[DB01183 DB06642] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06642|Bevasiranib VEGFA common genes common pathways GO:0007595| lactation CREB1;VEGFA GO:0010629| negative regulation of gene expression ESR1;OPRD1;VEGFA;CREB1 GO:1900745| VEGFA;OPRK1 GO:0060749| mammary gland alveolus development ESR1;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0043066| negative regulation of apoptotic process ALB;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;VEGFA GO:0002576| platelet degranulation ALB;VEGFA GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:0001666| response to hypoxia VEGFA;CREB1 GO:0010628| positive regulation of gene expression VEGFA;TLR4 GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;VEGFA;OPRM1 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA GO:0071456| cellular response to hypoxia VEGFA;OPRD1 GO:0030154| cell differentiation VEGFA;CREB1 10504:[DB01183 DB11182] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SLCO1A2;TF;LTF GO:0044267| cellular protein metabolic process LTF;TF;ALB;LYZ GO:0001895| retina homeostasis TF;LTF;LYZ;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0098869| ALB GO:0002376| immune system process TLR4;LTF GO:0006898| receptor-mediated endocytosis ALB GO:0006355| regulation of transcription, DNA-dependent CREB1;LTF;ESR1 GO:0042742| defense response to bacterium LTF;LYZ;TLR4 GO:0043687| post-translational protein modification ALB;TF GO:0006954| inflammatory response LYZ;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity LTF;TLR4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006351| transcription, DNA-dependent CREB1;LTF;ESR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;TLR4 GO:0043066| negative regulation of apoptotic process ALB;LTF GO:0008152| metabolic process UGT1A1;LYZ;CES1 GO:0050829| defense response to Gram-negative bacterium LTF;TLR4;LYZ GO:0002576| platelet degranulation TF;ALB GO:0045087| innate immune response TLR4;LTF 10505:[DB01183 DB08708] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08708|N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 GO:0006468| protein phosphorylation PIM1;CREB1 10506:[DB01183 DB07482] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 10507:[DB01183 DB03940] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03940|Oxamic Acid LDHA;LDHB;SLC16A3 common genes common pathways GO:0014070| response to organic cyclic compound LDHA;UGT1A1 GO:0055085| transmembrane transport SLCO1A2;SLC16A3;ABCB1 GO:0001666| response to hypoxia LDHA;CREB1 GO:0043627| response to estrogen stimulus OPRK1;LDHA;ESR1 GO:0007584| response to nutrient LDHA;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;LDHA GO:0042493| response to drug CREB1;LDHA;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;LDHB;LDHA 10508:[DB01183 DB04770] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways 10509:[DB01183 DB06709] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06709|Methacholine CHRM3 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 GO:0007165| signal transduction CREB1;TLR4;CHRM3;OPRK1;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;OPRD1;OPRM1 10510:[DB01183 DB06813] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06813|Pralatrexate DHFR;TYMS;FPGS;SLC19A1 common genes common pathways GO:0045471| response to ethanol OPRK1;TYMS;UGT1A1;OPRM1 GO:0001889| liver development FPGS;UGT1A1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0007623| circadian rhythm TYMS;CREB1 GO:0055114| oxidation-reduction process DHFR;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;CREB1;TYMS;UGT1A1 GO:0007568| aging CREB1;TYMS GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0031100| organ regeneration UGT1A1;FPGS GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0009636| response to toxin CES1;TYMS 10511:[DB01183 DB08339] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ABL1;TLR4 GO:0002322| B cell proliferation involved in immune response ABL1;TLR4 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;ABL1 GO:0006468| protein phosphorylation ABL1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CREB1;ESR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TLR4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0045087| innate immune response ABL1;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;ABL1;OPRK1 GO:0043065| positive regulation of apoptotic process ABL1;CREB1 10512:[DB01183 DB05362] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05362|SSR-126517E F10 common genes common pathways 10513:[DB01183 DB05069] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways GO:0006811| ion transport CHRNA9;CHRNA10;SLCO1A2 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;CHRNA9;OPRM1;ESR1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA10;CHRNA9 GO:0007165| signal transduction CHRNA9;CREB1;TLR4;CHRNA10;OPRK1;OPRM1;OPRD1;ESR1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;CHRNA9;CHRNA10 10514:[DB01183 DB08526] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08526|CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE CTSH common genes common pathways GO:0010628| positive regulation of gene expression CTSH;TLR4 GO:0044267| cellular protein metabolic process ALB;CTSH GO:0043066| negative regulation of apoptotic process ALB;CTSH 10515:[DB01183 DB06229] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug HTR2B;HTR2C;ADRA1A;DRD2;ABCB1;CREB1;UGT1A1;HTR2A GO:0007268| synaptic transmission HTR2C;OPRK1;HTR2A;OPRM1;OPRD1 GO:0043278| response to morphine OPRM1;OPRK1;DRD2 GO:0008542| visual learning CREB1;DRD2;HRH1 GO:0035094| response to nicotine CREB1;DRD2 GO:0016032| viral reproduction CREB1;HTR2A GO:0006954| inflammatory response TLR4;HRH1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HTR2B GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0019233| sensory perception of pain HTR2A;OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol OPRM1;DRD2;OPRK1;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1D;OPRK1;HTR2B;HTR2C;ADRA1A;HTR2A;ESR1;HRH1;OPRD1;OPRM1;ADRA1B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0048148| behavioral response to cocaine HTR2A;DRD2;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;DRD2;ESR1 GO:0007626| locomotory behavior HTR2C;OPRK1;DRD2;OPRM1 GO:0042220| response to cocaine OPRK1;DRD2;OPRM1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;TLR4;ADRA1A;DRD2;HTR2B;HTR2C GO:0009636| response to toxin CES1;DRD2 GO:0007409| axonogenesis DRD2;CREB1 GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1;OPRK1 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0001666| response to hypoxia CREB1;DRD2 GO:0045600| positive regulation of fat cell differentiation HTR2C;CREB1;HTR2A GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007568| aging HTR2A;CREB1;ADRA1A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1 GO:0007613| memory CREB1;HTR2A;HRH1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;HTR2A;ESR1;OPRM1;ADRA1B GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;HTR2B;HTR2C;OPRK1;ADRA1A;DRD2;ADRA1D;ADRA1B;ADRA2C;HTR2A;ADRA2B;OPRM1;HRH1;OPRD1 GO:0007165| signal transduction ADRA1B;ADRA2C;ESR1;HTR2A;ADRA2B;OPRM1;HRH1;OPRD1;ADRA2A;HTR2B;HTR2C;OPRK1;ADRA1A;DRD2;CREB1;TLR4;ADRA1D GO:0007610| behavior HTR2A;HTR2B;HTR2C;OPRK1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:1900273| CREB1;DRD2 10516:[DB01183 DB04018] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04018|S-Isopropyl-Isothiourea NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0055114| oxidation-reduction process CYP3A4;NOS3;CYP2C8 10517:[DB01183 DB02551] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02551|6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0001666| response to hypoxia CREB1;PLAU GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;PLAU;TLR4;CREB1 10518:[DB01183 DB05630] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05630|Sodium stibogluconate TOP1 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process TOP1;CREB1 GO:0007623| circadian rhythm CREB1;TOP1 GO:0016032| viral reproduction CREB1;TOP1 GO:0042493| response to drug TOP1;CREB1;UGT1A1;ABCB1 10519:[DB01183 DB02527] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0010033| response to organic substance ABCC4;UGT1A1;CREB1 GO:0055085| transmembrane transport ABCB1;ABCC11;ABCC5;SLC22A6;ABCC4;SLC22A7;SLCO1A2;HCN2;SLC22A8 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKAR2B GO:0009636| response to toxin SLC22A8;CES1 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0006811| ion transport SLC22A7;SLC22A8;HCN2;SLCO1A2 GO:0015711| organic anion transport SLCO1A2;SLC22A7;SLC22A6;ABCC5;ABCC11 GO:0006810| transport ABCB1;ABCC5 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A7;SLC22A8;SLCO1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;ABCC4 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;ABCC4 GO:0002576| platelet degranulation ALB;ABCC4 GO:0006357| regulation of transcription from RNA polymerase II promoter PRKAR1A;ESR1 10520:[DB01183 DB07954] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PDE3B;OPRM1;OPRD1;PDE4D;PDE7A;OPRK1;PDE8A;PDE2A GO:0050729| positive regulation of inflammatory response TLR4;PDE2A GO:0007568| aging PDE4D;CREB1 GO:0070588| calcium ion transmembrane transport OPRM1;PDE2A GO:0007165| signal transduction PDE3B;ESR1;PDE4D;OPRD1;OPRM1;OPRK1;PDE7A;PDE9A;TLR4;CREB1;PDE2A;PDE8A;PDE5A GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PDE8A GO:0000187| activation of MAPK activity TLR4;PDE6G GO:0032729| positive regulation of interferon-gamma production TLR4;PDE4D GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;PDE4D GO:0008152| metabolic process UGT1A1;PDE5A;PDE2A;CES1 GO:0071560| cellular response to transforming growth factor beta stimulus PDE2A;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;ESR1 GO:0071260| cellular response to mechanical stimulus TLR4;PDE2A GO:0006355| regulation of transcription, DNA-dependent PDE8A;CREB1;ESR1 GO:0043086| negative regulation of catalytic activity PDE6G;UGT1A1 GO:0043951| negative regulation of cAMP-mediated signaling PDE3B;OPRM1 10521:[DB01183 DB05168] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways GO:0006954| inflammatory response FOLR2;TLR4 GO:0006898| receptor-mediated endocytosis FOLR1;FOLR2;ALB 10522:[DB01183 DB08889] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0016032| viral reproduction PSMB10;PSMB9;PSMB2;PSMB1;PSMB5;CREB1;PSMB8 GO:0042493| response to drug ABCB1;UGT1A1;CREB1 GO:0043687| post-translational protein modification ALB;PSMB8;PSMB10;PSMB9;PSMB2;PSMB1;PSMB5 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0002376| immune system process PSMB9;PSMB10;PSMB8;TLR4 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0030154| cell differentiation PSMB8;CREB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0016579| protein deubiquitination PSMB10;ESR1;PSMB2;PSMB9;PSMB5;PSMB1;PSMB8 GO:0014070| response to organic cyclic compound PSMB2;UGT1A1 GO:0055085| transmembrane transport PSMB8;ABCB1;PSMB9;PSMB2;PSMB5;PSMB1;SLCO1A2;PSMB10 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 10523:[DB01183 DB00984] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0006810| transport ABCB1;AR GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;AR GO:0030879| mammary gland development CYP19A1;CREB1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development AR;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0016579| protein deubiquitination AR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0060065| uterus development CYP19A1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;AR GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AR;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP19A1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 10524:[DB01183 DB11605] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0007165| signal transduction ESR1;OPRM1;NR1H4;OPRD1;OPRK1;CREB1;NR1I2;TLR4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0032715| negative regulation of interleukin-6 production NR1H4;TLR4 GO:0002376| immune system process TLR4;NR1H4 GO:0032720| negative regulation of tumor necrosis factor production NR1H4;TLR4 GO:0032689| negative regulation of interferon-gamma production NR1H4;TLR4 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;NR1I2;UGT1A1;CYP3A4;CYP3A7 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0048511| rhythmic process PPARA;CREB1 GO:0010628| positive regulation of gene expression NR1I2;TLR4 GO:0001666| response to hypoxia CREB1;PPARA GO:0042359| vitamin D metabolic process CYP3A4 GO:0015721| bile acid and bile salt transport SLCO1A2;NR1H4;ALB GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0034142| toll-like receptor 4 signaling pathway TLR4;NR1H4 GO:0006629| lipid metabolic process CYP3A4;PPARA GO:0006706| steroid catabolic process CYP3A4 GO:0045087| innate immune response NR1H4;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA;NR1H4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;NR1I2;CES1;CYP3A4;CYP3A7 GO:0071398| cellular response to fatty acid CREB1;NR1H4 GO:0043066| negative regulation of apoptotic process ALB;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TLR4;CREB1;NR1H4;ESR1;PPARA GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;NR1H4 GO:0043401| steroid hormone mediated signaling pathway NR1I2;NR1H4;PPARA;ESR1 GO:0006351| transcription, DNA-dependent NR1I2;CREB1;NR1H4;PPARA;ESR1 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade NR1H4;ESR1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042060| wound healing OPRM1;PPARA GO:0006357| regulation of transcription from RNA polymerase II promoter NR1H4;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;NR1H4;ESR1;PPARA GO:0042752| regulation of circadian rhythm CREB1;PPARA GO:0006954| inflammatory response TLR4;NR1H4 GO:1901215| PPARA;CREB1 GO:0042742| defense response to bacterium TLR4;NR1H4 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP3A43;CYP3A4;CYP3A7 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;ESR1;CREB1;NR1I2 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent NR1I2;CREB1;NR1H4;PPARA;ESR1 10525:[DB01183 DB08602] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PDE7A;OPRD1;OPRM1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;PDE7A;OPRK1 10526:[DB01183 DB06728] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06728|Aniline KLK1;ALB;CYP2E1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8;UGT1A1 GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C8 GO:0043069| negative regulation of programmed cell death ALB GO:0042493| response to drug CYP2E1;UGT1A1;CREB1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CES1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol UGT1A1;OPRK1;CYP2E1;OPRM1 10527:[DB01183 DB00522] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00522|Bentiromide HPN common genes common pathways GO:0010628| positive regulation of gene expression TLR4;HPN GO:0043066| negative regulation of apoptotic process HPN;ALB 10528:[DB01183 DB02004] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 10529:[DB01183 DB05047] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways GO:0006810| transport GRIA3;GRIA4;ABCB1 GO:0007165| signal transduction GRIA2;ESR1;OPRM1;OPRD1;OPRK1;GRIA1;CREB1;TLR4 GO:0006811| ion transport SLCO1A2;GRIA3;GRIA2;GRIA4;GRIA1 GO:0007411| axon guidance CREB1;BDNF GO:0060079| regulation of excitatory postsynaptic membrane potential GRIA4;GRIA1;GRIA3;OPRM1;GRIA2 GO:0007268| synaptic transmission OPRK1;GRIA1;OPRD1;OPRM1;GRIA2 10530:[DB01183 DB07614] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways GO:0007165| signal transduction HPGDS;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0006629| lipid metabolic process CYP3A4;HPGDS GO:0007626| locomotory behavior OPRM1;HPGDS;OPRK1 10531:[DB01183 DB07838] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07838|(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE NMT2 common genes common pathways 10532:[DB01183 DB00876] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCC2 GO:0043627| response to estrogen stimulus ABCC2;OPRK1;ESR1 GO:0050729| positive regulation of inflammatory response TLR4;AGTR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;AGTR1 GO:0006810| transport ABCC2;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;AGTR1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;AGTR1;TLR4;CREB1;OPRK1 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ABCC2 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1;TLR4;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;AGTR1;ESR1;OPRM1;OPRD1 GO:0050727| regulation of inflammatory response AGTR1;ESR1;TLR4 GO:0071222| cellular response to lipopolysaccharide ABCC2;OPRK1;TLR4 GO:0033762| response to glucagon stimulus CREB1;ABCC2 10533:[DB01183 DB05316] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1;HTR2A GO:0042493| response to drug CREB1;UGT1A1;DRD2;ABCB1;HTR2A GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0035094| response to nicotine CREB1;DRD2 GO:0043278| response to morphine OPRK1;DRD2;OPRM1 GO:0008542| visual learning CREB1;DRD2 GO:0016032| viral reproduction HTR2A;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1;OPRK1 GO:0045471| response to ethanol OPRK1;DRD2;UGT1A1;OPRM1 GO:0019233| sensory perception of pain HTR2A;OPRM1;OPRD1;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;DRD2;ESR1 GO:0007626| locomotory behavior OPRM1;DRD2;OPRK1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;DRD2;OPRM1;HTR2A GO:0042220| response to cocaine DRD2;OPRK1;OPRM1 GO:0007409| axonogenesis CREB1;DRD2 GO:0009636| response to toxin DRD2;CES1 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A GO:0007613| memory CREB1;HTR2A GO:0007568| aging HTR2A;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRM1;OPRD1;OPRK1;DRD2 GO:0007610| behavior HTR2A;OPRK1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;DRD2;ESR1;HTR2A;OPRM1;OPRD1 GO:1900273| DRD2;CREB1 10534:[DB01183 DB05607] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05607|PRX-08066 HTR2B common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ABCB1;HTR2B GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HTR2B GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1;HTR2B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HTR2B GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2B;TLR4;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway HTR2B;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;HTR2B;ESR1;OPRD1;OPRM1 GO:0007610| behavior HTR2B;OPRK1 10535:[DB01183 DB03125] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR 10536:[DB01183 DB02140] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02140|N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide CTSH common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CTSH GO:0044267| cellular protein metabolic process CTSH;ALB GO:0010628| positive regulation of gene expression CTSH;TLR4 10537:[DB01183 DB04714] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;FDPS GO:0006695| cholesterol biosynthetic process CES1;FDPS;GGPS1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction CREB1;FDPS 10538:[DB01183 DB06979] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06979|5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;HAO1;CYP3A4 10539:[DB01183 DB08795] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC15A2;SLC22A5;SLCO1A2 GO:0006811| ion transport SLC15A1;SLCO1A2;SLC22A5;SLC15A2 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0015711| organic anion transport SLCO1A2;SLC22A5 10540:[DB01183 DB07340] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07340|N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine AURKB;INCENP common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter AURKB;ESR1 GO:0006468| protein phosphorylation AURKB;CREB1 GO:0007568| aging AURKB;CREB1 10541:[DB01183 DB13421] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13421|Edoxudine ALB common genes ALB common pathways GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB 10542:[DB01183 DB12023] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways GO:0007165| signal transduction OPRM1;IL5RA;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0006955| immune response TLR4;OPRK1;FCGR3A;OPRD1 10543:[DB01183 DB05423] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05423|ORG-34517 NR3C1 common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;OPRM1;NR3C1;OPRD1 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;TLR4;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR3C1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 10544:[DB01183 DB06898] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06898|4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol ESR1;NCOA2 common genes ESR1 common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0048511| rhythmic process CREB1;NCOA2 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0006351| transcription, DNA-dependent NCOA2;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TLR4;CREB1;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060065| uterus development ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 10545:[DB01183 DB04477] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04477|N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GAPDHS;CYP2C8 10546:[DB01183 DB05415] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05415|OSI-461 PDE5A common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;PDE5A;ESR1;OPRD1;OPRM1 GO:0008152| metabolic process UGT1A1;PDE5A;CES1 10547:[DB01183 DB00431] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00431|Lindane GABRB1;GLRA1;GLRA2;GLRA3;GLRB;GABRB3;GABRR1;PGR;ESR1;NR1I2 common genes ESR1 common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PGR;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;PGR GO:0042738| exogenous drug catabolic process NR1I2;CYP2C8;CYP3A4 GO:0007268| synaptic transmission GLRA2;GABRR1;GLRA3;OPRM1;OPRD1;OPRK1;GLRB;GLRA1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PGR;CREB1;NR1I2 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:1901215| GABRB3;CREB1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;NR1I2;CES1;CYP3A4 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;NR1I2;TLR4;CREB1;ESR1 GO:0007218| neuropeptide signaling pathway GLRA2;GLRA3;OPRD1;OPRM1;OPRK1;GLRB;GLRA1 GO:0071361| cellular response to ethanol GLRA2;UGT1A1;GLRA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0071294| cellular response to zinc ion CREB1;GLRA1;GLRA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway NR1I2;PGR;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NR1I2;PGR;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;GLRA2;GLRA1;GLRB GO:0010628| positive regulation of gene expression NR1I2;TLR4 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0009636| response to toxin GABRB1;CES1 GO:0030879| mammary gland development PGR;CREB1 GO:0006811| ion transport GLRB;GLRA1;GLRA2;GABRB3;GABRR1;GLRA3;GABRB1;SLCO1A2 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction TLR4;NR1I2;CREB1;PGR;OPRK1;GABRB1;OPRD1;OPRM1;ESR1;GABRB3 GO:0008202| steroid metabolic process CYP3A4;NR1I2;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus ESR1 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0006810| transport ABCB1;GABRB1;GABRR1;GABRB3 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 10548:[DB01183 DB06896] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;MET;OPRM1;OPRD1 GO:0006468| protein phosphorylation CREB1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET;CREB1;TLR4 10549:[DB01183 DB03981] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways GO:0043086| negative regulation of catalytic activity UGT1A1;ANXA5 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;ESR1;CREB1 GO:0002576| platelet degranulation ANXA5;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;FGF2;ESR1 GO:0043066| negative regulation of apoptotic process ANXA5;ALB GO:0042060| wound healing FGF2;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;ANXA5 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;FGF2;OPRM1 GO:0000187| activation of MAPK activity TLR4;FGF2 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;FGF2;ANXA5;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1;FGF2 GO:0030154| cell differentiation CREB1;FGF2 GO:0072089| stem cell proliferation FGF2;ABCB1 10550:[DB01183 DB07968] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways GO:0008152| metabolic process UGT1A1;PYGL;CES1 GO:0070266| necroptosis PYGL;TLR4 10551:[DB01183 DB03987] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity DHFR;ESR1 GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 10552:[DB01183 DB04076] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CES1;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006955| immune response OPRD1;TLR4;PNP;OPRK1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;UGT1A1;PNP;CREB1;CYP1A2 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 10553:[DB01183 DB06512] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06512|Deramciclane HTR2A;HTR2C;CYP2D6 common genes common pathways GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0007626| locomotory behavior OPRM1;HTR2C;OPRK1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;HTR2A GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1;OPRK1;HTR2C GO:0016032| viral reproduction CREB1;HTR2A GO:0007268| synaptic transmission OPRM1;OPRD1;HTR2A;HTR2C;OPRK1 GO:0042493| response to drug HTR2A;ABCB1;HTR2C;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0007165| signal transduction HTR2C;OPRK1;CREB1;TLR4;ESR1;HTR2A;OPRM1;OPRD1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007610| behavior HTR2A;HTR2C;OPRK1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;HTR2A;OPRK1;HTR2C GO:0007568| aging HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory HTR2A;CREB1 GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;CREB1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;HTR2C;TLR4 10554:[DB01183 DB07403] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways GO:0006468| protein phosphorylation CREB1;PDK1 10555:[DB01183 DB05971] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05971|Archexin AKT1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;AKT1;OPRK1 GO:0071363| cellular response to growth factor stimulus CREB1;AKT1;OPRD1 GO:0007568| aging AKT1;CREB1 GO:0030154| cell differentiation AKT1;CREB1 GO:0006468| protein phosphorylation CREB1;AKT1 GO:0071456| cellular response to hypoxia OPRD1;AKT1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;AKT1;OPRM1 GO:0007249| I-kappaB kinase/NF-kappaB cascade AKT1;TLR4 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;AKT1;OPRD1;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;AKT1 GO:0045600| positive regulation of fat cell differentiation AKT1;CREB1 GO:0010033| response to organic substance AKT1;CREB1;UGT1A1 GO:0046889| positive regulation of lipid biosynthetic process AKT1;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity AKT1;ESR1 GO:0000060| protein import into nucleus, translocation OPRD1;AKT1 GO:0060079| regulation of excitatory postsynaptic membrane potential AKT1;OPRM1 GO:0031663| lipopolysaccharide-mediated signaling pathway AKT1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;AKT1 GO:0043065| positive regulation of apoptotic process AKT1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AKT1;TLR4;CREB1 GO:0071260| cellular response to mechanical stimulus TLR4;AKT1 GO:1990090| AKT1;CREB1 GO:0042981| regulation of apoptotic process CREB1;AKT1;ESR1 GO:0032094| response to food AKT1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;AKT1;ESR1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;AKT1;ESR1 GO:1901215| AKT1;CREB1 GO:0043491| protein kinase B signaling cascade CREB1;AKT1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;AKT1 GO:0006954| inflammatory response TLR4;AKT1 10556:[DB01183 DB02996] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02996|2-(Thiomethylene)-4-Methylpentanoic Acid ADAM28 common genes common pathways 10557:[DB01183 DB03821] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03821|2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid ARSA;ARSA common genes common pathways GO:0043687| post-translational protein modification ALB;ARSA GO:0008152| metabolic process UGT1A1;CES1;ARSA 10558:[DB01183 DB08856] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08856|DADLE SLCO1B1 common genes common pathways GO:0015711| organic anion transport SLCO1B1;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;ALB GO:0006811| ion transport SLCO1A2;SLCO1B1 GO:0055085| transmembrane transport SLCO1A2;SLCO1B1;ABCB1 10559:[DB01183 DB07447] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0007586| digestion UGT1A1;AKR1D1 GO:0006629| lipid metabolic process AKR1D1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;AKR1D1;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1;AKR1D1 GO:0008202| steroid metabolic process CYP3A4;AKR1D1;CYP2C8;UGT1A1 10560:[DB01183 DB08729] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways GO:0007165| signal transduction OPRK1;PDE5A;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0008152| metabolic process UGT1A1;PDE5A;CES1 10561:[DB01183 DB09037] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09037|Pembrolizumab PDCD1 common genes common pathways GO:0007165| signal transduction OPRM1;PDCD1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0002376| immune system process PDCD1;TLR4 GO:0043066| negative regulation of apoptotic process PDCD1;ALB GO:0043065| positive regulation of apoptotic process CREB1;PDCD1 10562:[DB01183 DB11752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11752|Bryostatin 1 CYP3A4 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 10563:[DB01183 DB00498] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00498|Phenindione VKORC1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C8;VKORC1;CYP3A4 GO:0055114| oxidation-reduction process VKORC1;CYP3A4;CYP2C8 10564:[DB01183 DB08878] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process CYP3A4;DHFR;CYP2C8 GO:0055085| transmembrane transport SLC46A1;SLCO1A2;ABCB1 10565:[DB01183 DB14146] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes ABCB1;OPRK1;OPRD1;OPRM1 common pathways GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0051881| regulation of mitochondrial membrane potential OPRD1 GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1 GO:1901381| OPRK1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1 GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0045332| phospholipid translocation ABCB1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0071315| cellular response to morphine OPRM1 GO:0071456| cellular response to hypoxia OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0042908| xenobiotic transport ABCB1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0006810| transport ABCB1 GO:0044849| OPRM1;OPRK1 GO:1990708| OPRK1 GO:0070588| calcium ion transmembrane transport OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0007610| behavior OPRK1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:0051607| defense response to virus OPRK1 GO:0032094| response to food OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042711| maternal behavior OPRK1 GO:0006955| immune response TLR4;OPRK1;OPRD1 GO:0097237| OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:1903937| OPRK1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0032100| positive regulation of appetite OPRM1 GO:0043278| response to morphine OPRK1;OPRM1 GO:0007600| sensory perception OPRM1;OPRK1 GO:0042060| wound healing OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:1901529| ABCB1 GO:0033554| cellular response to stress OPRM1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;OPRK1 GO:0009314| response to radiation OPRM1;OPRK1 GO:0007626| locomotory behavior OPRM1;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0048148| behavioral response to cocaine OPRK1 GO:1903715| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:1900745| OPRK1 10566:[DB01183 DB14029] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14029|Furafylline CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;TLR4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 10567:[DB01183 DB09107] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways GO:0007165| signal transduction EPOR;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 10568:[DB01183 DB03005] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 10569:[DB01183 DB04903] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways GO:0006810| transport ABCB1;GABRA3 GO:0006811| ion transport GABRA2;GABRA3;SLCO1A2 10570:[DB01183 DB04273] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04273|8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine PNMT common genes common pathways 10571:[DB01183 DB02831] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02831|Dihydrogenphosphate DCXR common genes common pathways GO:0055114| oxidation-reduction process DCXR;CYP3A4;CYP2C8 10572:[DB01183 DB00649] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0055085| transmembrane transport SLCO1A2;SLC22A6;ABCB1 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0015711| organic anion transport SLC22A6;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 10573:[DB01183 DB13200] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13200|Lipegfilgrastim CSF3R common genes common pathways GO:0007165| signal transduction CSF3R;TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1 10574:[DB01183 DB07406] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways GO:0006468| protein phosphorylation CREB1;MAPKAPK2 GO:0002224| toll-like receptor signaling pathway TLR4;MAPKAPK2 GO:0000187| activation of MAPK activity TLR4;MAPKAPK2 GO:0032496| response to lipopolysaccharide OPRM1;MAPKAPK2;TLR4;UGT1A1 GO:0006954| inflammatory response TLR4;MAPKAPK2 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process MAPKAPK2;TLR4 10575:[DB01183 DB01643] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01643|Thymidine monophosphate tmk;DTYMK;dnaQ;TYMS;thyA;topA common genes common pathways GO:0042493| response to drug CREB1;TYMS;UGT1A1;ABCB1 GO:0007623| circadian rhythm CREB1;TYMS GO:0045471| response to ethanol OPRK1;UGT1A1;TYMS;OPRM1 GO:0043627| response to estrogen stimulus ESR1;DTYMK;OPRK1 GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0009636| response to toxin TYMS;CES1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0071363| cellular response to growth factor stimulus CREB1;DTYMK;OPRD1 GO:0007568| aging TYMS;CREB1 10576:[DB01183 DB00727] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0008152| metabolic process UGT1A1;ALDH2;CES1 GO:0055114| oxidation-reduction process CYP2C8;ALDH2;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;NPR1 GO:0006468| protein phosphorylation NPR1;CREB1 10577:[DB01183 DB00785] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007165| signal transduction CHRM4;OPRK1;CHRM3;CREB1;TLR4;OPRM1;CHRM5;OPRD1;ESR1;CHRM1;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;CHRM4;CHRM2;CHRM1;OPRD1;CHRM5;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007586| digestion UGT1A1;CHRM3 10578:[DB01183 DB13014] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13014|Hypericin GSTA1;GSTP1;ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;GSTP1 GO:0008152| metabolic process CES1;GSTP1;GSTA1;UGT1A1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;GSTP1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol OPRM1;OPRK1;GSTP1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0098869| ALB;GSTP1;GSTA1 GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin CES1;GSTP1 GO:0001895| retina homeostasis ALB GO:0030855| epithelial cell differentiation CES1;GSTA1 GO:0044267| cellular protein metabolic process ALB 10579:[DB01183 DB05197] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05197|Sofalcone CBR1 common genes common pathways GO:0030855| epithelial cell differentiation CES1;CBR1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CBR1;CYP3A4 GO:0055114| oxidation-reduction process CBR1;CYP3A4;CYP2C8 10580:[DB01183 DB07369] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;MET GO:0006468| protein phosphorylation CREB1;MET GO:0007165| signal transduction OPRD1;OPRM1;MET;ESR1;TLR4;CREB1;OPRK1 10581:[DB01183 DB12742] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0042060| wound healing PDGFRA;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;KIT GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;MET;ESR1 GO:0009314| response to radiation OPRK1;OPRM1;KIT GO:0042981| regulation of apoptotic process CREB1;ESR1;FLT3 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;RAD51;RET GO:0045893| positive regulation of transcription, DNA-dependent CREB1;RET;ESR1 GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0006954| inflammatory response TLR4;KIT GO:0016032| viral reproduction CREB1;PDGFRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;KIT GO:0008542| visual learning KIT;CREB1 GO:0048863| stem cell differentiation KIT;ESR1 GO:0030154| cell differentiation FLT3;CREB1 GO:0006468| protein phosphorylation FLT3;MET;KIT;RET;CREB1;PDGFRA GO:0007204| elevation of cytosolic calcium ion concentration PDGFRA;ESR1;OPRM1 GO:0043069| negative regulation of programmed cell death KIT;ALB GO:0031100| organ regeneration FLT3;UGT1A1 GO:0010863| positive regulation of phospholipase C activity KIT;ESR1;PDGFRA GO:0007165| signal transduction OPRD1;OPRM1;MET;ESR1;KIT;RET;TLR4;CREB1;OPRK1 GO:0009636| response to toxin RAD51;CES1 GO:0014070| response to organic cyclic compound UGT1A1;RAD51 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PDGFRA GO:0000187| activation of MAPK activity TLR4;KIT GO:0008584| male gonad development ESR1;KIT GO:0010628| positive regulation of gene expression TLR4;KIT;RET GO:0048146| positive regulation of fibroblast proliferation ESR1;PDGFRA GO:0007411| axon guidance RET;CREB1 10582:[DB01183 DB02240] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02240|Quinacrine mustard TPR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;ESR1 GO:0016032| viral reproduction TPR;CREB1 10583:[DB01183 DB08240] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways GO:0002576| platelet degranulation ALDOA;ALB 10584:[DB01183 DB08697] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08697|4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0001666| response to hypoxia CREB1;PLAU GO:0007165| signal transduction PLAU;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 10585:[DB01183 DB06043] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06043|Olaratumab PDGFRA common genes common pathways GO:0010863| positive regulation of phospholipase C activity PDGFRA;ESR1 GO:0006468| protein phosphorylation CREB1;PDGFRA GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;PDGFRA GO:0048146| positive regulation of fibroblast proliferation ESR1;PDGFRA GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;PDGFRA;TLR4 GO:0042060| wound healing PDGFRA;OPRM1 GO:0016032| viral reproduction PDGFRA;CREB1 10586:[DB01183 DB01579] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;SLC6A2;ADRA1A;ABCB1 GO:0007268| synaptic transmission SLC6A2;OPRK1;OPRD1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;OPRD1;OPRM1;ESR1;ADRA1B GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC6A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;OPRM1;OPRD1;OPRK1;ADRA1A GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;OPRM1;ESR1;ADRA1A GO:0007568| aging CREB1;ADRA1A GO:0006810| transport ABCB1;SLC6A2 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;ADRA1B;TLR4;CREB1;ADRA1A;OPRK1 10587:[DB01183 DB05964] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0007623| circadian rhythm SLC6A4;CREB1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;DRD2;OPRK1 GO:0048148| behavioral response to cocaine DRD2;OPRK1 GO:0007626| locomotory behavior OPRM1;DRD2;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;DRD2;TLR4;CREB1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0007268| synaptic transmission OPRM1;OPRD1;SLC6A2;OPRK1 GO:0042493| response to drug UGT1A1;SLC6A2;CREB1;DRD2;ABCB1;SLC6A4 GO:0035094| response to nicotine DRD2;CREB1 GO:0043278| response to morphine DRD2;OPRK1;OPRM1 GO:0008542| visual learning DRD2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;DRD2;OPRD1;OPRM1 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0007613| memory SLC6A4;CREB1 GO:1900273| DRD2;CREB1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;DRD2;OPRK1;TLR4;CREB1 GO:0009636| response to toxin DRD2;CES1;SLC6A4 GO:0007409| axonogenesis DRD2;CREB1 GO:0042220| response to cocaine OPRK1;DRD2;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;DRD2 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLCO1A2;SLC6A4 GO:0010628| positive regulation of gene expression TLR4;SLC6A4 GO:0001666| response to hypoxia SLC6A4;DRD2;CREB1 GO:0010033| response to organic substance UGT1A1;CREB1;SLC6A4 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0007584| response to nutrient SLC6A4;UGT1A1 10588:[DB01183 DB01262] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01262|Decitabine DNMT1;DCK common genes common pathways GO:0006351| transcription, DNA-dependent DNMT1;ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;DNMT1;ESR1 GO:0010628| positive regulation of gene expression DNMT1;TLR4 10589:[DB01183 DB05129] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways GO:0007623| circadian rhythm CREB1;TOP1 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;TOP2A GO:0042493| response to drug CREB1;UGT1A1;ABCB1;TOP1 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0016032| viral reproduction CREB1;TOP1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process TOP2A;CREB1;TOP1 10590:[DB01183 DB07359] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07359|3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide GCK common genes common pathways GO:0008152| metabolic process CES1;GCK;UGT1A1 10591:[DB01183 DB06663] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0007584| response to nutrient SSTR1;SSTR2;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger SSTR3;OPRD1;OPRM1;SSTR5;SSTR1;SSTR2 GO:0008285| negative regulation of cell proliferation SSTR5;OPRM1;SSTR3;SSTR2;SSTR1 GO:1990830| CREB1;SSTR1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0071392| cellular response to estradiol stimulus SSTR1;UGT1A1;SSTR2;ESR1;SSTR3 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;SSTR2;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;SSTR1;SSTR2;SSTR5;SSTR3;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction SSTR2;CREB1;SSTR1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;SSTR3;SSTR5 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0007268| synaptic transmission SSTR5;SSTR3;OPRD1;OPRM1;OPRK1 GO:0071385| cellular response to glucocorticoid stimulus SSTR3;SSTR5;SSTR2;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0007586| digestion SSTR1;SSTR2;UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0042594| response to starvation SSTR2;UGT1A1;SSTR1;SSTR3 GO:0007218| neuropeptide signaling pathway SSTR1;SSTR2;OPRK1;SSTR3;OPRD1;OPRM1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 10592:[DB01183 DB07753] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR GO:0006810| transport ABCB1;TTR 10593:[DB01183 DB00082] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP27A1;CYP2C18;CYP4A11;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042493| response to drug CREB1;UGT1A1;BCHE;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP3A4;CES1;CYP2C18 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP4A11;CYP2C18 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0000187| activation of MAPK activity TLR4;GHR GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;CYP3A4 GO:0097267| CYP2C19;CYP2C8;CYP4A11 GO:0032870| cellular response to hormone stimulus UGT1A1;GHR GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0040018| positive regulation of multicellular organism growth CREB1;GHR GO:0009267| cellular response to starvation GLUL;ALB GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0032355| response to estradiol stimulus GHR;ESR1 10594:[DB01183 DB07875] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07875|5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide F10 common genes common pathways 10595:[DB01183 DB01034] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways GO:0030879| mammary gland development CREB1;FASN GO:0055114| oxidation-reduction process CYP2C8;FASN;CYP3A4 GO:0006629| lipid metabolic process FASN;CYP3A4 GO:0008152| metabolic process FASN;UGT1A1;CES1 10596:[DB01183 DB07555] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways 10597:[DB01183 DB07011] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0032496| response to lipopolysaccharide NOS2;TLR4;UGT1A1;OPRM1 GO:0007623| circadian rhythm NOS2;CREB1 GO:0055114| oxidation-reduction process NOS2;CYP2C8;CYP3A4 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0009617| response to bacterium NOS2;TLR4 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;NOS2 GO:0001666| response to hypoxia CREB1;NOS2 10598:[DB01183 DB08773] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08773|RALOXIFENE CORE ESR1;NCOA2 common genes ESR1 common pathways GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NCOA2 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2 GO:0060065| uterus development ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;NCOA2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NCOA2;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport ALB;NCOA2;SLCO1A2 GO:0008584| male gonad development ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:1903799| ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0032355| response to estradiol stimulus ESR1 10599:[DB01183 DB03867] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways GO:0098869| GSR;ALB GO:0055114| oxidation-reduction process CYP2C8;GSR;CYP3A4 10600:[DB01183 DB03568] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03568|Butyric Acid BCHE;BCHE common genes common pathways GO:0042493| response to drug ABCB1;CREB1;UGT1A1;BCHE GO:0008285| negative regulation of cell proliferation BCHE;OPRM1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 10601:[DB01183 DB01861] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 10602:[DB01183 DB03046] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03046|7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0007165| signal transduction OPRK1;PLAU;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0001666| response to hypoxia CREB1;PLAU 10603:[DB01183 DB04557] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes ALB common pathways GO:0042060| wound healing PPARA;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR1H4;RXRA GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;NR1H4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006351| transcription, DNA-dependent CREB1;RXRA;ESR1;PPARA;NR1H4 GO:0043401| steroid hormone mediated signaling pathway RXRA;NR1H4;ESR1;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;RXRA;TLR4;NR1H4;PPARA;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;NR1H4 GO:0002576| platelet degranulation ALB GO:0050727| regulation of inflammatory response ESR1;FABP4;TLR4 GO:0043066| negative regulation of apoptotic process ALB;NR1H4 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP2C8;CYP2C9 GO:0071398| cellular response to fatty acid CREB1;NR1H4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0045087| innate immune response NR1H4;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA;NR1H4;RXRA GO:0007586| digestion FABP2;UGT1A1 GO:0006629| lipid metabolic process CYP2C9;PTGS1;PPARA;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent NR1H4;PPARA;ESR1;CREB1;RXRA GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;ESR1;RXRA;CREB1 GO:0042742| defense response to bacterium TLR4;NR1H4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;PTGS1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:1901215| PPARA;CREB1 GO:0006954| inflammatory response NR1H4;PTGS1;TLR4 GO:0016032| viral reproduction RXRA;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARA;NR1H4;RXRA GO:0042752| regulation of circadian rhythm CREB1;PPARA GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0051659| maintenance of mitochondrion location ALB GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2C8;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO2A1;SLCO1A2 GO:0050729| positive regulation of inflammatory response FABP4;TLR4 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0002376| immune system process NR1H4;TLR4 GO:0032720| negative regulation of tumor necrosis factor production NR1H4;TLR4 GO:0006898| receptor-mediated endocytosis ALB GO:0032689| negative regulation of interferon-gamma production TLR4;NR1H4 GO:0032715| negative regulation of interleukin-6 production NR1H4;TLR4 GO:0098869| PTGS1;ALB GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;NR1H4;OPRD1;ESR1 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0034142| toll-like receptor 4 signaling pathway NR1H4;TLR4 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0055085| transmembrane transport SLCO2A1;ABCB1;SLCO1A2 GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0015721| bile acid and bile salt transport SLCO1A2;NR1H4;RXRA;ALB GO:0001666| response to hypoxia PPARA;CREB1 GO:0048511| rhythmic process CREB1;PPARA 10604:[DB01183 DB09300] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM2;OPRK1;CHRM3 GO:0007165| signal transduction TLR4;CREB1;CHRM3;OPRK1;CHRM2;ESR1;OPRD1;OPRM1 GO:0007586| digestion UGT1A1;CHRM3 10605:[DB01183 DB03884] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03884|Phenylpyruvic acid HAO1;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;HAO1 GO:0055085| transmembrane transport SLC16A3;ABCB1;SLCO1A2 10606:[DB01183 DB02082] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways 10607:[DB01183 DB05831] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05831|ING-1 EPCAM common genes common pathways GO:0048863| stem cell differentiation ESR1;EPCAM GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;EPCAM;ESR1 10608:[DB01183 DB06995] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways GO:0006468| protein phosphorylation CREB1;MET GO:0007165| signal transduction OPRD1;OPRM1;MET;ESR1;TLR4;CREB1;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ESR1;CREB1;TLR4 10609:[DB01183 DB07929] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07929|N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE NR1H3;RXRB common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RXRB;NR1H3;ESR1 GO:0042752| regulation of circadian rhythm CREB1;NR1H3 GO:0006355| regulation of transcription, DNA-dependent NR1H3;CREB1;RXRB;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR1H3;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H3;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;RXRB;CREB1;NR1H3 GO:0071222| cellular response to lipopolysaccharide OPRK1;NR1H3;TLR4 GO:0043401| steroid hormone mediated signaling pathway NR1H3;RXRB;ESR1 GO:0006351| transcription, DNA-dependent NR1H3;RXRB;CREB1;ESR1 10610:[DB01183 DB07479] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways GO:0016579| protein deubiquitination ESR1;POLB GO:0007568| aging POLB;CREB1 GO:0006954| inflammatory response POLB;TLR4 GO:0045471| response to ethanol OPRM1;POLB;UGT1A1;OPRK1 10611:[DB01183 DB03784] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03784|Elaidoylamide PLA2G2A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2A GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;PLA2G2A;TLR4 GO:0050729| positive regulation of inflammatory response PLA2G2A;TLR4 10612:[DB01183 DB06199] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06199|Atrasentan EDNRA common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;EDNRA;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;EDNRA GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDNRA;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;EDNRA;OPRK1 GO:0001666| response to hypoxia CREB1;EDNRA 10613:[DB01183 DB04998] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04998|AGRO100 IKBKG common genes common pathways GO:0000187| activation of MAPK activity IKBKG;TLR4 GO:0016579| protein deubiquitination ESR1;IKBKG GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKG;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;IKBKG GO:0006355| regulation of transcription, DNA-dependent CREB1;IKBKG;ESR1 GO:1901215| IKBKG;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IKBKG GO:0006954| inflammatory response TLR4;IKBKG GO:0016032| viral reproduction IKBKG;CREB1 GO:0006955| immune response OPRD1;TLR4;IKBKG;OPRK1 GO:0002756| MyD88-independent toll-like receptor signaling pathway TLR4;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TLR4 GO:0006351| transcription, DNA-dependent IKBKG;CREB1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG;CREB1;TLR4 GO:0045087| innate immune response TLR4;IKBKG 10614:[DB01183 DB08130] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1 GO:0010628| positive regulation of gene expression TLR4;MAP2K1 GO:0000187| activation of MAPK activity MAP2K1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;MAP2K1;OPRM1 GO:0007165| signal transduction MAP2K1;OPRD1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0006468| protein phosphorylation CREB1;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;MAP2K1;CREB1 GO:0010629| negative regulation of gene expression MAP2K1;ESR1;OPRD1;CREB1 GO:0042981| regulation of apoptotic process ESR1;MAP2K1;CREB1 10615:[DB01183 DB00028] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;C5;C3;OPRM1;OPRD1 GO:0002376| immune system process C3;C5;FCGR1B;C4B;TLR4;FCGR2A;FCGR1A;C4A GO:0006898| receptor-mediated endocytosis FCGR1B;FCGR1A;ALB;FCGR2B GO:0007165| signal transduction TLR4;FCGR2B;CREB1;OPRK1;FCGR1A;C3;ESR1;OPRD1;FCGR2C;OPRM1 GO:0000187| activation of MAPK activity C5;TLR4 GO:0044267| cellular protein metabolic process ALB;C4A;C3 GO:1904646| TLR4;FCGR2B GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0045087| innate immune response C4B;C3;C5;FCGR1A;C4A;TLR4 GO:0006629| lipid metabolic process C3;CYP3A4 GO:0009617| response to bacterium FCGR2B;TLR4 GO:0043687| post-translational protein modification C3;C4A;ALB GO:0006954| inflammatory response TLR4;FCGR2B;C4A;C3;C5;C4B GO:0016032| viral reproduction FCGR2B;CREB1 GO:0006955| immune response OPRD1;FCGR2C;FCGR1B;FCGR3A;C3;FCGR1A;OPRK1;TLR4;FCGR2B;FCGR3B 10616:[DB01183 DB04622] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways 10617:[DB01183 DB01442] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRD1;OPRM1;OPRK1 GO:0032355| response to estradiol stimulus ESR1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging HTR2A;CREB1;SLC6A3 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1 GO:0007613| memory HTR2A;SLC6A4;CREB1 GO:0007610| behavior OPRK1;HTR2A GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0007165| signal transduction ESR1;HTR2A;OPRM1;OPRD1;CREB1;TLR4;OPRK1 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0009636| response to toxin MAOB;SLC18A2;CES1;SLC6A4 GO:0042220| response to cocaine OPRM1;SLC6A3;OPRK1 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLC18A2;SLCO1A2;SLC18A1;SLC6A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;TLR4 GO:0006855| drug transmembrane transport ABCB1;SLC18A1 GO:0001666| response to hypoxia CREB1;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0045600| positive regulation of fat cell differentiation CREB1;HTR2A GO:0010033| response to organic substance CREB1;UGT1A1;SLC6A4 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0032496| response to lipopolysaccharide MAOB;UGT1A1;TLR4;OPRM1 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0019233| sensory perception of pain HTR2A;OPRM1;OPRD1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2A;ESR1;OPRD1;OPRM1 GO:0045471| response to ethanol OPRM1;MAOB;UGT1A1;OPRK1;SLC6A3 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0007626| locomotory behavior OPRM1;SLC18A2;SLC6A3;OPRK1 GO:0042493| response to drug SLC6A3;ABCB1;CREB1;SLC6A2;MAOB;UGT1A1;SLC6A4;HTR2A GO:0007268| synaptic transmission HTR2A;SLC18A2;OPRD1;OPRM1;SLC6A2;OPRK1 GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP2C8;MAOB GO:0016032| viral reproduction HTR2A;CREB1 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007595| lactation CREB1;SLC6A3 10618:[DB01183 DB06980] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06980|(2S)-2-(1H-indol-3-yl)hexanoic acid SKP1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;SKP1 GO:0043687| post-translational protein modification ALB;SKP1 10619:[DB01183 DB07760] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07760|3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;ALB GO:0016032| viral reproduction UNG;CREB1 10620:[DB01183 DB06900] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways 10621:[DB01183 DB00218] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;TOP2A;CREB1;ESR1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0048511| rhythmic process TOP2A;CREB1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 10622:[DB01183 DB13530] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13530|Mepindolol CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 10623:[DB01183 DB08842] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08842|Acetylcarnitine SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport SLCO1A2;SLC22A5;ABCB1 GO:0006811| ion transport SLC22A5;SLCO1A2 GO:0015711| organic anion transport SLCO1A2;SLC22A5 10624:[DB01183 DB03708] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways GO:0008152| metabolic process CES1;PAPSS1;UGT1A1 10625:[DB01183 DB05199] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05199|LX1031 TPH1 common genes common pathways GO:0045600| positive regulation of fat cell differentiation CREB1;TPH1 GO:0060749| mammary gland alveolus development TPH1;ESR1 GO:0007623| circadian rhythm TPH1;CREB1 GO:0055114| oxidation-reduction process TPH1;CYP2C8;CYP3A4 10626:[DB01183 DB05882] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05882|CHF 4227 ESR1;ESR2 common genes ESR1 common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060065| uterus development ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;CREB1;TLR4 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;ESR2 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 10627:[DB01183 DB08249] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0042594| response to starvation DHODH;UGT1A1 GO:0007595| lactation CREB1;DHODH GO:0042493| response to drug ABCB1;CREB1;UGT1A1;DHODH GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 10628:[DB01183 DB13165] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0042752| regulation of circadian rhythm CREB1;ROCK2 GO:0048511| rhythmic process ROCK2;CREB1 GO:0010628| positive regulation of gene expression TLR4;ROCK2;ROCK1 GO:0007165| signal transduction ROCK1;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0007249| I-kappaB kinase/NF-kappaB cascade ROCK1;TLR4;ROCK2 GO:0006468| protein phosphorylation CREB1;ROCK2;ROCK1 GO:0007186| G-protein coupled receptor signaling pathway ROCK2;ROCK1;OPRK1;OPRM1;OPRD1 10629:[DB01183 DB04779] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04779|ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways GO:0008152| metabolic process LCT;UGT1A1;CES1 10630:[DB01183 DB03346] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0045600| positive regulation of fat cell differentiation SULT1E1;CREB1 GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;SULT1E1;CYP3A4 GO:0008210| estrogen metabolic process SULT1E1;UGT1A1 10631:[DB01183 DB00686] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0030154| cell differentiation FGF2;FGF1;CREB1;FGF4 GO:0072089| stem cell proliferation ABCB1;FGF2 GO:0007165| signal transduction ESR1;FGF1;FGF2;OPRM1;OPRD1;CREB1;TLR4;OPRK1;FGF4 GO:0010863| positive regulation of phospholipase C activity FGF2;ESR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF4;TLR4;OPRM1;FGF2 GO:0000187| activation of MAPK activity TLR4;FGF2;FGF1 GO:1990830| CREB1;FGF4 GO:0010628| positive regulation of gene expression FGF4;TLR4 GO:0042060| wound healing FGF2;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;FGF4;ESR1;FGF1;FGF2 GO:0043066| negative regulation of apoptotic process ALB;FGF4 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;ESR1;CREB1 10632:[DB01183 DB07208] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0042493| response to drug CREB1;PPARG;UGT1A1;ABCB1 GO:0042752| regulation of circadian rhythm CREB1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process CREB1;PPARG GO:0043627| response to estrogen stimulus ESR1;OPRK1;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;PPARG;OPRK1 GO:0007165| signal transduction CREB1;PPARG;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0031100| organ regeneration PPARG;UGT1A1 10633:[DB01183 DB09093] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043069| negative regulation of programmed cell death ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB 10634:[DB01183 DB07744] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways GO:0001666| response to hypoxia CREB1;CASP1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;TLR4;CASP1;CREB1 GO:0050718| positive regulation of interleukin-1 beta secretion TLR4;CASP1 GO:0009617| response to bacterium TLR4;CASP1 GO:0071222| cellular response to lipopolysaccharide OPRK1;CASP1;TLR4 GO:0050727| regulation of inflammatory response TLR4;CASP1;ESR1 GO:0071260| cellular response to mechanical stimulus CASP1;TLR4 GO:0042981| regulation of apoptotic process CASP1;CREB1;ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CASP1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;TLR4 10635:[DB01183 DB13443] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13443|Esatenolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 10636:[DB01183 DB05642] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0045471| response to ethanol UGT1A1;HTR3A;OPRK1;OPRM1 GO:0042493| response to drug UGT1A1;SLC6A2;CREB1;ABCB1 GO:0007268| synaptic transmission SLC6A2;HTR3A;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;HTR3A;ESR1;OPRD1;OPRM1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;HTR3A GO:0006810| transport ABCB1;SLC6A2 GO:0006811| ion transport HTR3A;SLCO1A2 GO:0042220| response to cocaine HTR3A;OPRK1;OPRM1 GO:0055085| transmembrane transport ABCB1;SLC6A2;SLCO1A2 10637:[DB01183 DB08584] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways GO:0007165| signal transduction MET;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0006468| protein phosphorylation CREB1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ESR1;TLR4;CREB1 10638:[DB01183 DB04859] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04859|Zanapezil ACHE common genes common pathways 10639:[DB01183 DB12548] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12548|Sparsentan AGT;EDNRA common genes common pathways GO:0048146| positive regulation of fibroblast proliferation AGT;ESR1 GO:0001666| response to hypoxia CREB1;EDNRA GO:0007165| signal transduction OPRK1;TLR4;CREB1;EDNRA;ESR1;OPRD1;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process AGT;OPRM1;ESR1;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration AGT;OPRM1;ESR1;EDNRA GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1;EDNRA GO:0007568| aging CREB1;AGT GO:0007186| G-protein coupled receptor signaling pathway OPRK1;EDNRA;AGT;OPRD1;OPRM1 GO:0032355| response to estradiol stimulus AGT;ESR1 GO:0050729| positive regulation of inflammatory response AGT;TLR4 GO:0051924| regulation of calcium ion transport OPRD1;AGT GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AGT GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1;AGT GO:0045893| positive regulation of transcription, DNA-dependent AGT;ESR1;CREB1 GO:0042981| regulation of apoptotic process AGT;ESR1;CREB1 GO:0071260| cellular response to mechanical stimulus TLR4;AGT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;AGT;OPRD1;OPRM1;ESR1 10640:[DB01183 DB00245] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0042493| response to drug SLC6A3;ABCB1;CREB1;UGT1A1 GO:0008542| visual learning CREB1;HRH1 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007595| lactation CREB1;SLC6A3 GO:0006954| inflammatory response HRH1;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;HRH1;OPRD1;OPRM1 GO:0045471| response to ethanol UGT1A1;SLC6A3;OPRK1;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C19 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2D6;CYP2C8;CYP2C19 GO:0007626| locomotory behavior OPRM1;SLC6A3;OPRK1 GO:0042220| response to cocaine OPRK1;SLC6A3;OPRM1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLCO1A2 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0007568| aging SLC6A3;CREB1 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007613| memory HRH1;CREB1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8;CYP2C19 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;HRH1;CHRM1 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0097267| CYP2C19;CYP2C8 GO:0007165| signal transduction CHRM1;ESR1;HRH1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 10641:[DB01183 DB07269] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 10642:[DB01183 DB00792] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0007613| memory CREB1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway HRH1;OPRD1;OPRM1;OPRK1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1 GO:0007165| signal transduction OPRM1;HRH1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response TLR4;HRH1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;HRH1;OPRD1;ESR1;OPRK1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2D6 10643:[DB01183 DB05736] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05736|MIV-701 CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway CTSK;TLR4 10644:[DB01183 DB07115] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 10645:[DB01183 DB03477] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0010033| response to organic substance CREB1;UGT1A1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory PTGS2;CREB1 GO:0007568| aging CREB1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TLR4 GO:0098869| ALB;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0042493| response to drug PTGS2;CREB1;UGT1A1;ABCB1 GO:0006954| inflammatory response PTGS2;TLR4 GO:0019233| sensory perception of pain OPRK1;OPRD1;PTGS2;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;TLR4;UGT1A1 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 10646:[DB01183 DB05295] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05295|Eldecalcitol VDR common genes common pathways GO:0010628| positive regulation of gene expression VDR;TLR4 GO:0008285| negative regulation of cell proliferation VDR;OPRM1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;VDR;OPRD1;OPRM1;ESR1 GO:0006355| regulation of transcription, DNA-dependent VDR;ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1;VDR GO:0006367| transcription initiation from RNA polymerase II promoter VDR;ESR1 GO:0007595| lactation VDR;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;VDR GO:0006351| transcription, DNA-dependent CREB1;VDR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;VDR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;ESR1 10647:[DB01183 DB08566] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways GO:0007586| digestion CTRB1;UGT1A1 10648:[DB01183 DB08935] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08935|Obinutuzumab MS4A1 common genes common pathways 10649:[DB01183 DB03878] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways GO:0002322| B cell proliferation involved in immune response ABL1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;TLR4 GO:0006468| protein phosphorylation ABL1;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1;OPRM1 GO:0006355| regulation of transcription, DNA-dependent ABL1;CREB1;ESR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;ABL1 GO:0045087| innate immune response TLR4;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;ABL1;OPRK1 10650:[DB01183 DB05131] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05131|TTP889 F9 common genes common pathways 10651:[DB01183 DB07328] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 10652:[DB01183 DB08705] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08705|6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE PIM1 common genes common pathways GO:0006468| protein phosphorylation CREB1;PIM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;ALB 10653:[DB01183 DB03434] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways GO:0042742| defense response to bacterium GNLY;TLR4 10654:[DB01183 DB00429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00429|Carboprost tromethamine PTGER1 common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;PTGER1;OPRD1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;PTGER1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;PTGER1 10655:[DB01183 DB07899] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways GO:0007586| digestion UGT1A1;CTRB1 10656:[DB01183 DB00981] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0035094| response to nicotine CHRNA4;CHRNB2;CREB1 GO:0008542| visual learning CHRNB2;CREB1 GO:0007268| synaptic transmission OPRD1;OPRM1;CHRNA4;OPRK1 GO:0007626| locomotory behavior CHRNB2;OPRK1;OPRM1;CHRNA4 GO:0033603| positive regulation of dopamine secretion OPRK1;CHRNB2 GO:0019233| sensory perception of pain CHRNB2;OPRK1;OPRD1;OPRM1;CHRNA4 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNB2;CHRNA4;OPRM1 GO:0045471| response to ethanol OPRM1;OPRK1;CHRNB2;UGT1A1 GO:0030890| positive regulation of B cell proliferation CHRNB2;TLR4 GO:0001666| response to hypoxia CHRNA4;CREB1;CHRNB2 GO:0006811| ion transport SLCO1A2;CHRNA4;CHRNB2 GO:0042220| response to cocaine OPRM1;OPRK1;CHRNB2 GO:0007165| signal transduction OPRK1;CREB1;TLR4;CHRNB2;CHRNA4;ESR1;OPRM1;OPRD1 GO:0007613| memory CHRNB2;CREB1 10657:[DB01183 DB05507] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05507|VX-765 CASP1;IL1B common genes common pathways GO:0050718| positive regulation of interleukin-1 beta secretion CASP1;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;ESR1 GO:0006955| immune response TLR4;OPRK1;IL1B;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IL1B GO:0006954| inflammatory response IL1B;TLR4 GO:0009617| response to bacterium TLR4;CASP1 GO:0043491| protein kinase B signaling cascade IL1B;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;CREB1;ESR1 GO:1900745| IL1B;OPRK1 GO:0071260| cellular response to mechanical stimulus IL1B;CASP1;TLR4 GO:0042981| regulation of apoptotic process ESR1;CREB1;CASP1 GO:0042346| positive regulation of NF-kappaB import into nucleus IL1B;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;IL1B GO:0050727| regulation of inflammatory response CASP1;TLR4;ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;CASP1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IL1B;CREB1;TLR4 GO:0046330| positive regulation of JNK cascade IL1B;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;TLR4;IL1B GO:0032729| positive regulation of interferon-gamma production IL1B;TLR4 GO:0032496| response to lipopolysaccharide IL1B;UGT1A1;TLR4;CASP1;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;IL1B GO:0001666| response to hypoxia CASP1;CREB1 GO:0010628| positive regulation of gene expression IL1B;TLR4 GO:0000187| activation of MAPK activity IL1B;TLR4 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;IL1B;CREB1;CASP1;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;IL1B;TLR4 GO:0032755| positive regulation of interleukin-6 production IL1B;TLR4 GO:0032757| positive regulation of interleukin-8 production IL1B;TLR4 10658:[DB01183 DB08879] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08879|Belimumab TNFSF13B common genes common pathways GO:0007165| signal transduction TNFSF13B;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0002376| immune system process TLR4;TNFSF13B GO:0030890| positive regulation of B cell proliferation TLR4;TNFSF13B GO:0006955| immune response OPRD1;OPRK1;TNFSF13B;TLR4 10659:[DB01183 DB02134] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 10660:[DB01183 DB07846] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways 10661:[DB01183 DB06550] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06550|Bivatuzumab CD44 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;CD44 GO:0033138| positive regulation of peptidyl-serine phosphorylation CD44;OPRD1 GO:0043066| negative regulation of apoptotic process ALB;CD44 10662:[DB01183 DB05804] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes SLCO1A2 common pathways GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1;PTGS2 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ABCB11;SLCO1A2;ALB;SLCO2B1;SLC10A6 GO:0055085| transmembrane transport SLC22A8;ABCB11;SLCO1B1;SLCO1B3;SLCO1A2;SLC10A6;SLCO2B1;ABCB1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0009636| response to toxin CES1;SLC22A8 GO:0002933| CYP3A4;CYP3A7;CYP2C8 GO:0006811| ion transport SLC10A6;SLCO2B1;SLCO1A2;SLC22A8;SLCO1B1;SLCO1B3 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0015711| organic anion transport SLCO1A2;SLCO1B1;SLCO1B3 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TLR4 GO:0098869| ALB;PTGS2 GO:0006810| transport ABCB11;ABCB1 GO:0007568| aging CREB1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007613| memory CREB1;PTGS2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP3A7 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0006954| inflammatory response PTGS2;TLR4 GO:0055114| oxidation-reduction process CYP19A1;CYP2C8;CYP3A4;CYP3A7;PTGS2 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;PTGS2 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0060065| uterus development CYP19A1;ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP3A7 GO:0009314| response to radiation OPRM1;PTGS2;OPRK1 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;ESR1;TLR4 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1;UGT1A1;TLR4 10663:[DB01183 DB04144] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways GO:0043278| response to morphine OPRM1;MDM2;OPRK1 GO:0071391| cellular response to estrogen stimulus MDM2;ESR1 GO:0016032| viral reproduction CREB1;MDM2 GO:0043491| protein kinase B signaling cascade MDM2;CREB1 GO:0010629| negative regulation of gene expression CREB1;MDM2;ESR1;OPRD1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;MDM2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MDM2;ESR1 GO:0043066| negative regulation of apoptotic process ALB;MDM2 GO:0016579| protein deubiquitination ESR1;MDM2 GO:0010628| positive regulation of gene expression TLR4;MDM2 GO:0042220| response to cocaine MDM2;OPRK1;OPRM1 GO:0009636| response to toxin CES1;MDM2 GO:0048545| response to steroid hormone stimulus UGT1A1;MDM2 GO:0071456| cellular response to hypoxia OPRD1;MDM2 GO:0071363| cellular response to growth factor stimulus CREB1;MDM2;OPRD1 10664:[DB01183 DB07430] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways GO:0000187| activation of MAPK activity TLR4;MAPKAPK2 GO:0002224| toll-like receptor signaling pathway TLR4;MAPKAPK2 GO:0006468| protein phosphorylation MAPKAPK2;CREB1 GO:0042535| positive regulation of tumor necrosis factor biosynthetic process MAPKAPK2;TLR4 GO:0006954| inflammatory response TLR4;MAPKAPK2 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;MAPKAPK2 10665:[DB01183 DB03639] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways 10666:[DB01183 DB07563] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07563|1-{7-cyclohexyl-6-[4-(4-methylpiperazin-1-yl)benzyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 10667:[DB01183 DB11133] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;SREBF1;UGT1A1;PPARG GO:0030855| epithelial cell differentiation CES1;PPARG GO:0032868| response to insulin stimulus PPARA;OPRK1 GO:0001666| response to hypoxia CREB1;PPARA GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0010033| response to organic substance PPARG;CREB1;UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process CREB1;PPARG;PPARA GO:0009267| cellular response to starvation SREBF1;ALB GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;SREBF1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRM1;OPRD1 GO:0007568| aging PTGS2;CREB1;SREBF1 GO:0007613| memory PTGS2;CREB1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0098869| PTGS2;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TLR4 GO:0031100| organ regeneration UGT1A1;PPARG GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007165| signal transduction OPRK1;TLR4;PPARG;CREB1;ESR1;OPRD1;OPRM1 GO:0032094| response to food SREBF1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARA;PPARG;CREB1;SREBF1 GO:0042493| response to drug PPARG;CREB1;UGT1A1;SREBF1;ABCB1;PTGS2 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARA;CREB1;PPARG;SREBF1 GO:1901215| PPARA;CREB1 GO:0055114| oxidation-reduction process CYP2C8;ALOX5;CYP3A4;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006954| inflammatory response ALOX5;PTGS2;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1;PPARA GO:0042752| regulation of circadian rhythm PPARA;CREB1;PPARG GO:0042060| wound healing PPARA;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;SREBF1;ESR1 GO:0007623| circadian rhythm SREBF1;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;TLR4;UGT1A1 GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA;ESR1 GO:0006351| transcription, DNA-dependent SREBF1;CREB1;PPARG;PPARA;ESR1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;PTGS2 GO:0071398| cellular response to fatty acid CREB1;SREBF1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;CREB1;PTGS2 GO:0050727| regulation of inflammatory response TLR4;PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CREB1;TLR4;SREBF1;PPARA;ESR1 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process SREBF1;PPARG;PTGS2;PPARA;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0033762| response to glucagon stimulus SREBF1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;SREBF1;PPARA;ESR1 GO:0045087| innate immune response TLR4;PPARG 10668:[DB01183 DB02376] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02376|D-gluconhydroximo-1,5-lactam LCT common genes common pathways GO:0008152| metabolic process UGT1A1;LCT;CES1 10669:[DB01183 DB01353] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0006810| transport GRIK2;GABRA6;GABRA4;GABRA1;GABRA5;GABRA3;ABCB1 GO:0007613| memory CHRNA7;CREB1 GO:0007165| signal transduction CREB1;TLR4;GABRA5;OPRK1;GABRA6;ESR1;OPRM1;OPRD1;CHRNA7;GRIA2;CHRNA4 GO:1900273| CREB1;CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production TLR4;CHRNA7 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;TLR4 GO:0055085| transmembrane transport ABCB1;SLCO1A2;GRIK2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;TLR4 GO:0006811| ion transport GABRA3;GABRA5;GABRA2;SLCO1A2;GABRA1;GABRA4;GABRA6;GRIK2;GRIA2;CHRNA4;CHRNA7 GO:0001666| response to hypoxia CREB1;CHRNA7;CHRNA4 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;CHRNA4 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;CHRNA4;GRIA2;GRIK2;OPRM1 GO:0007626| locomotory behavior OPRK1;OPRM1;CHRNA4 GO:0007268| synaptic transmission OPRK1;GABRA5;GRIA2;CHRNA4;GRIK2;OPRD1;OPRM1 GO:0035094| response to nicotine CREB1;CHRNA7;CHRNA4 10670:[DB01183 DB07845] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07845|2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide MAPK8 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAPK8;TLR4 GO:0071222| cellular response to lipopolysaccharide MAPK8;OPRK1;TLR4 GO:0043065| positive regulation of apoptotic process MAPK8;CREB1 GO:0043066| negative regulation of apoptotic process MAPK8;ALB GO:0042752| regulation of circadian rhythm MAPK8;CREB1 GO:0006468| protein phosphorylation MAPK8;CREB1 GO:0048511| rhythmic process MAPK8;CREB1 GO:0010628| positive regulation of gene expression MAPK8;TLR4 10671:[DB01183 DB04537] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways GO:0010628| positive regulation of gene expression WARS;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;WARS 10672:[DB01183 DB13934] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13934|Ligandrol AR common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;CREB1;TLR4 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0016579| protein deubiquitination AR;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development AR;ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;AR;TLR4;CREB1;OPRK1 GO:0006810| transport ABCB1;AR 10673:[DB01183 DB04985] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04985|Tigapotide RPSA common genes common pathways GO:0016032| viral reproduction CREB1;RPSA 10674:[DB01183 DB05141] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05141|LY2181308 BIRC5 common genes common pathways GO:0006468| protein phosphorylation CREB1;BIRC5 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;BIRC5 GO:0006351| transcription, DNA-dependent CREB1;BIRC5;ESR1 GO:0042981| regulation of apoptotic process ESR1;BIRC5;CREB1 GO:0043066| negative regulation of apoptotic process BIRC5;ALB GO:0006355| regulation of transcription, DNA-dependent ESR1;BIRC5;CREB1 10675:[DB01183 DB00395] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00395|Carisoprodol GABRA1;GABRB2;GABRG2;CYP2C19 common genes common pathways GO:1901215| GABRB2;CREB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8 GO:0007268| synaptic transmission OPRM1;GABRG2;OPRD1;OPRK1;GABRB2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0006811| ion transport SLCO1A2;GABRG2;GABRA1;GABRB2 GO:0006810| transport GABRG2;GABRA1;ABCB1;GABRB2 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;UGT1A1;CYP3A4 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19;UGT1A1 10676:[DB01183 DB00058] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways GO:0002438| acute inflammatory response to antigenic stimulus ELANE;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;ELANE GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ELANE GO:0042742| defense response to bacterium TLR4;ELANE GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;ELANE 10677:[DB01183 DB04398] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO2A1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLCO2B1 GO:0055085| transmembrane transport SLCO2A1;SLC16A3;ABCB1;SLCO2B1;SLC16A7;SLCO1A2;SLC16A10;SLC16A1 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO2B1;ALB GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0032094| response to food SLC16A1;OPRM1 10678:[DB01183 DB13174] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes CYP3A4 common pathways GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP3A5;CYP2D6;CYP2C8;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP2C8;CYP3A5;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C9;UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0097267| CYP1A2;CYP2C9;CYP2C8 GO:0002933| CYP3A5;CYP2C8;CYP3A4;CYP3A7 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression NR1H2;TLR4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR1H2 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1;UGT1A1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway NR1H3;NR1H2;ESR1 GO:0006351| transcription, DNA-dependent NR1H3;CREB1;NR1H2;ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;NR1H3;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;NR1H2;TLR4;CREB1;ESR1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C8;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CES1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H3;NR1H2;ESR1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP1A2;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1;NR1H2;CREB1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2;CYP2E1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1H2;CREB1;NR1H3 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR1H2;NR1H3;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A5;CYP2D6;CYP2C8;CYP3A7;CYP1A2;CYP3A4;CYP2E1;ALOX5;CYP3A43 GO:0006954| inflammatory response ALOX5;TLR4 GO:0042752| regulation of circadian rhythm NR1H3;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1H3;NR1H2 10679:[DB01183 DB05099] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05099|Ancrod FGA common genes common pathways GO:0002376| immune system process FGA;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;FGA;OPRK1;TLR4;CREB1 GO:0002224| toll-like receptor signaling pathway TLR4;FGA GO:0044267| cellular protein metabolic process FGA;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;FGA GO:0002576| platelet degranulation FGA;ALB GO:0045087| innate immune response FGA;TLR4 GO:0043687| post-translational protein modification FGA;ALB 10680:[DB01183 DB11359] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11359|Guaiacol ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 10681:[DB01183 DB07161] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways GO:0008285| negative regulation of cell proliferation JAK2;OPRM1 GO:0007165| signal transduction JAK2;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0002376| immune system process JAK2;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;JAK2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;JAK2 GO:0006468| protein phosphorylation JAK2;CREB1 GO:0030154| cell differentiation JAK2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;JAK2;OPRK1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;JAK2 GO:0050729| positive regulation of inflammatory response JAK2;TLR4 GO:0032760| positive regulation of tumor necrosis factor production JAK2;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;ESR1 GO:0042981| regulation of apoptotic process JAK2;CREB1;ESR1 GO:0045087| innate immune response JAK2;TLR4 GO:0050727| regulation of inflammatory response ESR1;JAK2;TLR4 GO:0043065| positive regulation of apoptotic process JAK2;CREB1 GO:0032496| response to lipopolysaccharide JAK2;UGT1A1;TLR4;OPRM1 10682:[DB01183 DB03677] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways GO:0010628| positive regulation of gene expression TLR4;EPHX2 GO:0009636| response to toxin CES1;EPHX2 GO:0017144| drug metabolic process EPHX2;CYP3A4;UGT1A1;CYP2C8 GO:0006954| inflammatory response EPHX2;TLR4 GO:0008152| metabolic process CES1;EPHX2;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2C8;EPHX2 GO:0006629| lipid metabolic process CYP3A4;EPHX2 10683:[DB01183 DB11738] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11738|Rilmenidine ADRA2A common genes common pathways GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADRA2A;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A;OPRK1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007165| signal transduction CREB1;TLR4;ADRA2A;OPRK1;ESR1;OPRM1;OPRD1 10684:[DB01183 DB08009] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways GO:0006468| protein phosphorylation CAMK1G;CREB1 GO:0008152| metabolic process UGT1A1;CES1;CAMK1G 10685:[DB01183 DB03886] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03886|Biopterin SPR;PTS;DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP3A4;SPR 10686:[DB01183 DB02530] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways GO:0007194| negative regulation of adenylate cyclase activity GABBR2;GABBR1;OPRM1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;GABBR2 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;GABBR1;OPRD1;GABBR2;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;GABBR1;OPRK1 GO:0007165| signal transduction GABBR1;OPRM1;OPRD1;ESR1;GABBR2;OPRK1;CREB1;TLR4 GO:0006811| ion transport SLCO1A2;SLC36A1 GO:0055085| transmembrane transport ABCB1;SLC36A1;SLCO1A2 10687:[DB01183 DB05879] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05879|AME-527 TNF common genes common pathways GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;TNF GO:0010629| negative regulation of gene expression OPRD1;ESR1;TNF;CREB1 GO:0042742| defense response to bacterium TNF;TLR4 GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0006955| immune response TNF;TLR4;OPRK1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0006954| inflammatory response TLR4;TNF GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0046330| positive regulation of JNK cascade TNF;TLR4 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0043065| positive regulation of apoptotic process TNF;CREB1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0050727| regulation of inflammatory response TNF;TLR4;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNF;TLR4;CREB1 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;OPRK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TNF GO:0000187| activation of MAPK activity TNF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;TNF;OPRM1 GO:0010628| positive regulation of gene expression TNF;TLR4 GO:0010033| response to organic substance UGT1A1;TNF;CREB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TLR4;ESR1;OPRM1 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TNF;TLR4 GO:0032757| positive regulation of interleukin-8 production TNF;TLR4 GO:0032722| positive regulation of chemokine production TNF;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 10688:[DB01183 DB11186] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes OPRM1;OPRK1 common pathways GO:1900745| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:1903715| OPRK1 GO:0048148| behavioral response to cocaine OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0009314| response to radiation OPRK1;OPRM1 GO:0007218| neuropeptide signaling pathway OPRK1;OPRM1;OPRD1 GO:0007626| locomotory behavior OPRK1;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0042060| wound healing OPRM1 GO:0007600| sensory perception OPRM1;OPRK1 GO:0043278| response to morphine OPRK1;OPRM1 GO:0032100| positive regulation of appetite OPRM1 GO:1903937| OPRK1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0006955| immune response OPRD1;OPRK1;TLR4 GO:0042711| maternal behavior OPRK1 GO:0040017| positive regulation of locomotion OPRK1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0048149| behavioral response to ethanol OPRM1 GO:0032094| response to food OPRM1 GO:0051607| defense response to virus OPRK1 GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0007610| behavior OPRK1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0070588| calcium ion transmembrane transport OPRM1 GO:1990708| OPRK1 GO:0044849| OPRK1;OPRM1 GO:0038003| opioid receptor signaling pathway OPRK1;SIGMAR1;OPRD1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071315| cellular response to morphine OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:1901381| OPRK1;KCNH2 GO:0008285| negative regulation of cell proliferation OPRM1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0046877| regulation of saliva secretion OPRK1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 GO:0042220| response to cocaine OPRK1;OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0055085| transmembrane transport ABCB1;KCNH2;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0042755| eating behavior OPRK1;OPRM1;OPRD1 GO:0006811| ion transport KCNH2;SLCO1A2 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 10689:[DB01183 DB13877] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13877|Iniparib PARP1 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0006366| transcription from RNA polymerase II promoter ESR1;PARP1;CREB1 GO:1904646| PARP1;TLR4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PARP1 GO:0071294| cellular response to zinc ion PARP1;CREB1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PARP1;TLR4;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 10690:[DB01183 DB04476] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04476|Trencam-3,2-Hopo LCN2 common genes common pathways GO:0006811| ion transport LCN2;SLCO1A2 GO:0002376| immune system process TLR4;LCN2 GO:0045087| innate immune response LCN2;TLR4 10691:[DB01183 DB08325] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways GO:0043491| protein kinase B signaling cascade MERTK;CREB1 GO:0060068| vagina development MERTK;ESR1 GO:0006468| protein phosphorylation CREB1;MERTK;CSNK1G1 10692:[DB01183 DB07449] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0006338| chromatin remodeling PADI4;ESR1 GO:0002376| immune system process TLR4;PADI4 GO:0006355| regulation of transcription, DNA-dependent ESR1;PADI4;CREB1 GO:0006351| transcription, DNA-dependent CREB1;PADI4;ESR1 GO:0045087| innate immune response TLR4;PADI4 10693:[DB01183 DB01279] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01279|Galsulfase PLIN3 common genes common pathways 10694:[DB01183 DB00388] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0097267| CYP1A2;CYP2C8 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;ADRA1B;ADRA1D;TLR4;CREB1;ADRA1A;OPRK1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0007568| aging ADRA1A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1D;ADRA1B;ESR1;OPRM1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;OPRD1;OPRM1;ADRA1A;OPRK1;ADRA1D GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0008285| negative regulation of cell proliferation OPRM1;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;ADRA1A GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1D;OPRK1;ADRA1A;ESR1;OPRD1;OPRM1;ADRA1B GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;MAOA;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1;ADRA1A 10695:[DB01183 DB07933] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07933|Erteberel ESR2;ESR1 common genes ESR1 common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;ESR2 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1;ESR2 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR2;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 10696:[DB01183 DB07283] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07283|9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response TLR4;ESR1;FABP4 GO:0050729| positive regulation of inflammatory response TLR4;FABP4 10697:[DB01183 DB09085] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09085|Tetracaine RYR1;RYR2 common genes common pathways GO:0070588| calcium ion transmembrane transport RYR2;OPRM1;RYR1 GO:0001666| response to hypoxia RYR2;CREB1;RYR1 GO:0055085| transmembrane transport SLCO1A2;RYR1;ABCB1;RYR2 GO:0006811| ion transport RYR2;RYR1;SLCO1A2 10698:[DB01183 DB06560] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06560|Pascolizumab IL4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CREB1;IL4;ESR1 GO:0006955| immune response IL4;TLR4;OPRK1;OPRD1 GO:0045348| positive regulation of MHC class II biosynthetic process IL4;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;IL4;ESR1 GO:0043066| negative regulation of apoptotic process ALB;IL4 GO:0045671| negative regulation of osteoclast differentiation IL4;TLR4 GO:0030890| positive regulation of B cell proliferation TLR4;IL4 10699:[DB01183 DB05889] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:1901529| ABCB1 10700:[DB01183 DB05367] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05367|Actelion-1 EDNRA common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway EDNRA;OPRK1;OPRM1;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDNRA;OPRK1;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;EDNRA GO:0007165| signal transduction EDNRA;CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1 GO:0001666| response to hypoxia CREB1;EDNRA 10701:[DB01183 DB00719] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00719|Azatadine HRH1;CYP3A4 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;HRH1;OPRD1;OPRK1 GO:0006954| inflammatory response HRH1;TLR4 GO:0008542| visual learning HRH1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0007165| signal transduction ESR1;OPRD1;HRH1;OPRM1;OPRK1;TLR4;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HRH1;OPRD1;OPRK1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007613| memory HRH1;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 10702:[DB01183 DB08499] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways GO:0014070| response to organic cyclic compound CASP3;UGT1A1 GO:0010033| response to organic substance CASP3;UGT1A1;CREB1 GO:0001666| response to hypoxia CREB1;CASP3 GO:0032355| response to estradiol stimulus CASP3;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;CASP3 GO:0042493| response to drug CASP3;ABCB1;CREB1;UGT1A1 GO:0035094| response to nicotine CASP3;CREB1 GO:0097190| apoptotic signaling pathway CASP3;TLR4 GO:0042060| wound healing CASP3;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;CASP3;TLR4;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;CREB1 10703:[DB01183 DB01013] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes CYP3A4 common pathways GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0009636| response to toxin CES1;CYP1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0007568| aging CYP1A1;CREB1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP1A1;CYP2C8 GO:0007165| signal transduction NR3C1;OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP1A1;UGT1A1 GO:0097267| CYP1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP1A1 GO:0042493| response to drug CYP1A1;CREB1;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0032094| response to food CYP1A1;OPRM1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0042737| drug catabolic process CYP3A4 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0006351| transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;TLR4;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1;TLR4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 10704:[DB01183 DB12020] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes UGT1A1 common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A4;UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1 GO:0052695| cellular glucuronidation UGT1A4;UGT1A1 GO:0006789| bilirubin conjugation UGT1A4;UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A4;CES1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0001889| liver development UGT1A1 GO:1904224| UGT1A4;UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A4 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0010033| response to organic substance CREB1;UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A4 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A4 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;UGT1A4;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 10705:[DB01183 DB06235] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A9;UGT1A1;CYP2C8 GO:0097267| CYP2C8;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process UGT2B7;CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;CREB1;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1;UGT2B7 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2C8 GO:0052695| cellular glucuronidation UGT1A9;UGT1A1;UGT2B7 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0008152| metabolic process UGT1A1;UGT1A9;CES1;UGT2B7 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C8;CYP3A4;CES1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;UGT2B7 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:1904224| UGT1A9;UGT1A1 10706:[DB01183 DB04971] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;CREB1;PPARA;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0042060| wound healing PPARA;OPRM1 GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA GO:0042594| response to starvation UGT1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARA;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;PPARA;ESR1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:1901215| CREB1;PPARA GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARA;PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;ESR1;PPARA GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PPARG GO:0042752| regulation of circadian rhythm CREB1;PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;PPARG GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;PPARG;TLR4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0032868| response to insulin stimulus OPRK1;PPARA GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance UGT1A1;CREB1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process PPARA;PPARG;CREB1 GO:0043627| response to estrogen stimulus OPRK1;PPARG;ESR1 GO:0001666| response to hypoxia CREB1;PPARA GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG 10707:[DB01183 DB00337] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes CYP3A4 common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;MTOR GO:0070588| calcium ion transmembrane transport OPRM1;FKBP1A GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRK1;MTOR;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0009267| cellular response to starvation ALB;MTOR GO:0071456| cellular response to hypoxia OPRD1;MTOR GO:0006468| protein phosphorylation CREB1;MTOR GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression TLR4;MTOR GO:0007584| response to nutrient UGT1A1;MTOR GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FKBP1A GO:0042220| response to cocaine OPRM1;OPRK1;MTOR GO:0036378| CYP3A4 GO:0050769| positive regulation of neurogenesis MTOR;OPRM1 GO:0032868| response to insulin stimulus MTOR;OPRK1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046889| positive regulation of lipid biosynthetic process MTOR;CREB1 GO:0042060| wound healing OPRM1;MTOR GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TLR4 GO:0008542| visual learning MTOR;CREB1 GO:0043278| response to morphine OPRK1;MTOR;OPRM1 GO:0008361| regulation of cell size CREB1;MTOR GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 10708:[DB01183 DB05092] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05092|CDP323 ITGA4 common genes common pathways 10709:[DB01183 DB01340] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0007586| digestion SLC15A1;UGT1A1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006811| ion transport SLC15A1;SLC15A2;SLCO1A2 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2;SLCO1A2 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 10710:[DB01183 DB01177] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01177|Idarubicin TOP2A;CYP2C9;CYP2D6;ABCC1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2D6;CYP2C8 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;ABCC1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;TOP2A;ESR1 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2D6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0055085| transmembrane transport ABCB1;ABCC1;SLCO1A2 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0048511| rhythmic process TOP2A;CREB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006810| transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C9;UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP2C9;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP2C9;CYP3A4 10711:[DB01183 DB01042] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways GO:0015711| organic anion transport SLC22A3;SLCO1A2 GO:0006810| transport ABCB1;SLC7A5 GO:0030154| cell differentiation SLC7A5;CREB1 GO:0006811| ion transport SLCO1A2;SLC22A3 GO:0006855| drug transmembrane transport SLC22A3;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A3;SLCO1A2 10712:[DB01183 DB05297] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0071456| cellular response to hypoxia BCL2;OPRD1 GO:0040018| positive regulation of multicellular organism growth CREB1;BCL2 GO:0051384| response to glucocorticoid stimulus BCL2;UGT1A1 GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;OPRD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;BCL2 GO:0055085| transmembrane transport ABCB1;SLCO1A2;BCL2 GO:0007409| axonogenesis BCL2;CREB1 GO:0009636| response to toxin CES1;BCL2 GO:0008285| negative regulation of cell proliferation OPRM1;BCL2 GO:0008584| male gonad development BCL2;ESR1 GO:0030890| positive regulation of B cell proliferation BCL2;TLR4 GO:0042981| regulation of apoptotic process ESR1;BCL2;CREB1 GO:0009314| response to radiation BCL2;OPRM1;OPRK1 GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0042493| response to drug UGT1A1;CREB1;ABCB1;BCL2 GO:0051607| defense response to virus BCL2;OPRK1 GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0035094| response to nicotine CREB1;BCL2 10713:[DB01183 DB03738] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 10714:[DB01183 DB00009] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PLG GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;FGA GO:0044267| cellular protein metabolic process PLG;ALB;FGA GO:0007165| signal transduction OPRD1;OPRM1;ESR1;FGA;PLAUR;OPRK1;TLR4;CREB1 GO:0032757| positive regulation of interleukin-8 production TLR4;SERPINE1 GO:0002376| immune system process FGA;TLR4 GO:0002224| toll-like receptor signaling pathway TLR4;FGA GO:0050729| positive regulation of inflammatory response SERPINE1;TLR4 GO:0043687| post-translational protein modification ALB;FGA GO:0045087| innate immune response TLR4;FGA GO:0002576| platelet degranulation PLG;FGA;ALB;SERPINE1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;SERPINE1 GO:0050829| defense response to Gram-negative bacterium TLR4;SERPINE1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;ESR1;CREB1;TLR4 GO:0043066| negative regulation of apoptotic process ALB;PLAUR GO:0007623| circadian rhythm SERPINE1;CREB1 10715:[DB01183 DB08890] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08890|Linaclotide GUCY2C common genes common pathways GO:0006468| protein phosphorylation GUCY2C;CREB1 GO:0009636| response to toxin CES1;GUCY2C GO:0007586| digestion GUCY2C;UGT1A1 10716:[DB01183 DB12364] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12364|Betrixaban F10;F2;ABCB1;KCNH2 common genes ABCB1 common pathways GO:0006953| acute-phase response UGT1A1;F2 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0006811| ion transport KCNH2;SLCO1A2 GO:0044267| cellular protein metabolic process F2;ALB GO:0055085| transmembrane transport ABCB1;SLCO1A2;KCNH2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:1901381| KCNH2;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;F2 GO:0072089| stem cell proliferation ABCB1 GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 10717:[DB01183 DB11134] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11134|Cupric oxide ALB;CP common genes ALB common pathways GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SLCO1A2;CP GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process CP;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB;CP GO:0055114| oxidation-reduction process CYP2C8;CP;CYP3A4 10718:[DB01183 DB07285] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways GO:0043065| positive regulation of apoptotic process CREB1;MMP9 GO:0043066| negative regulation of apoptotic process ALB;MMP9 10719:[DB01183 DB03390] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways GO:0051930| regulation of sensory perception of pain ACPP;OPRK1;OPRM1;OPRD1 10720:[DB01183 DB07419] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07419|S-23 AR common genes common pathways GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development ESR1;AR GO:0007165| signal transduction OPRK1;CREB1;TLR4;AR;ESR1;OPRM1;OPRD1 GO:0006810| transport ABCB1;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;AR;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR 10721:[DB01183 DB04689] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;PPARG;CREB1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm CREB1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0042493| response to drug PPARG;CREB1;UGT1A1;ABCB1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;PPARG;TLR4;OPRK1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG 10722:[DB01183 DB04577] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 10723:[DB01183 DB07069] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 10724:[DB01183 DB07728] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0042535| positive regulation of tumor necrosis factor biosynthetic process TLR4;MAPKAPK2 GO:0006954| inflammatory response TLR4;MAPKAPK2 GO:0032496| response to lipopolysaccharide MAPKAPK2;TLR4;MAPKAPK3;UGT1A1;OPRM1 GO:0000187| activation of MAPK activity MAPKAPK2;MAPKAPK3;TLR4 GO:0002224| toll-like receptor signaling pathway TLR4;MAPKAPK3;MAPKAPK2 GO:0006468| protein phosphorylation MAPKAPK3;CREB1;MAPKAPK2 GO:0007165| signal transduction TLR4;CREB1;MAPKAPK3;OPRK1;ESR1;OPRD1;OPRM1 10725:[DB01183 DB00509] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1C1;ALB;SLCO1A2;SLCO1B1 GO:0006811| ion transport SLCO4A1;SLCO1B1;SLCO1A2;SLCO4C1;SLCO1C1 GO:0055085| transmembrane transport SLCO1C1;SLCO4C1;ABCB1;SLCO1B1;SLCO1A2;SLCO4A1 GO:0006366| transcription from RNA polymerase II promoter THRA;CREB1;ESR1 GO:0098869| ALB;TPO GO:0015711| organic anion transport SLCO1C1;SLCO1B1;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1C1;ALB;SLCO4C1;SLCO1A2;SLCO1B1;SLCO4A1 GO:0006810| transport SLC7A5;ABCB1 GO:0030154| cell differentiation SLCO4C1;SLC7A5;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;THRA;THRB GO:0060509| Type I pneumocyte differentiation THRA;CREB1;THRB GO:0006355| regulation of transcription, DNA-dependent THRA;CREB1;THRB;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;TPO GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TLR4;CREB1;THRA;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;THRB;THRA GO:0006351| transcription, DNA-dependent THRB;THRA;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;THRB;THRA 10726:[DB01183 DB11118] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways GO:0001889| liver development UGT1A1;CPS1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CPS1 GO:0042981| regulation of apoptotic process GLS2;CREB1;ESR1 GO:0042594| response to starvation UGT1A1;CPS1 GO:0033762| response to glucagon stimulus CPS1;CREB1 GO:0008152| metabolic process UGT1A1;CPS1;CES1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CPS1 GO:0032094| response to food OPRM1;CPS1 GO:0051384| response to glucocorticoid stimulus UGT1A1;CPS1 GO:0009267| cellular response to starvation GLUL;ALB GO:0048545| response to steroid hormone stimulus UGT1A1;CPS1 GO:0009636| response to toxin CES1;CPS1 10727:[DB01183 DB08766] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08766|Zofenoprilat LAP3 common genes common pathways 10728:[DB01183 DB01809] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0030154| cell differentiation CREB1;HCK GO:0006468| protein phosphorylation CREB1;HCK;RET GO:0002376| immune system process HCK;TLR4 GO:0007165| signal transduction RET;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0010628| positive regulation of gene expression TLR4;RET GO:0007411| axon guidance CREB1;RET GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;HCK GO:0043066| negative regulation of apoptotic process HCK;ALB GO:0050727| regulation of inflammatory response TLR4;HCK;ESR1 GO:0045087| innate immune response TLR4;HCK GO:0045893| positive regulation of transcription, DNA-dependent ESR1;RET;CREB1 GO:0042493| response to drug RET;ABCB1;CREB1;UGT1A1 GO:0016032| viral reproduction CREB1;HCK GO:0006954| inflammatory response HCK;TLR4 10729:[DB01183 DB01765] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01765|(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ESR1;CREB1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;CSNK2A1;OPRD1;OPRM1;ESR1 GO:0048511| rhythmic process CREB1;CSNK2A1 10730:[DB01183 DB01549] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0042220| response to cocaine OPRK1;DRD2;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;DRD2 GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis CREB1;DRD2 GO:0006811| ion transport SLCO1A2;GRIN3A GO:0007165| signal transduction TLR4;CREB1;OPRK1;DRD2;ESR1;OPRD1;OPRM1 GO:1900273| DRD2;CREB1 GO:0070588| calcium ion transmembrane transport GRIN3A;OPRM1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;DRD2 GO:0008542| visual learning DRD2;CREB1 GO:0043278| response to morphine OPRM1;DRD2;OPRK1 GO:0035094| response to nicotine DRD2;CREB1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;DRD2 GO:0048148| behavioral response to cocaine OPRK1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;DRD2;ESR1 GO:0007626| locomotory behavior OPRM1;DRD2;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0045471| response to ethanol GRIN3A;UGT1A1;OPRK1;DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN3A;DRD2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 10731:[DB01183 DB06788] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06788|Histrelin GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GNRHR;OPRK1;OPRM1;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;OPRK1;GNRHR;TLR4;CREB1 10732:[DB01183 DB03612] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0042493| response to drug HADH;ABCB1;UGT1A1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;HADH;CYP3A4 GO:0006629| lipid metabolic process HADH;CYP3A4 GO:0032868| response to insulin stimulus HADH;OPRK1 GO:0014823| response to activity HADH;CREB1 10733:[DB01183 DB08399] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08399|PICEATANNOL ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 GO:0006811| ion transport ATP5B;SLCO1A2 10734:[DB01183 DB02422] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02422|Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside MAN1B1 common genes common pathways GO:0008152| metabolic process UGT1A1;MAN1B1;CES1 10735:[DB01183 DB07597] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07597|CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 10736:[DB01183 DB08287] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08287|(1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 10737:[DB01183 DB02457] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways GO:0006629| lipid metabolic process LIPF;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;LIPF;CYP2C8 10738:[DB01183 DB04057] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways GO:0031100| organ regeneration ATIC;UGT1A1 GO:0008152| metabolic process CES1;UGT1A1;ATIC 10739:[DB01183 DB08831] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08831|2-deoxyglucose SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLC2A1;SLCO1A2;ABCB1 GO:0032868| response to insulin stimulus OPRK1;SLC2A1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0071260| cellular response to mechanical stimulus TLR4;SLC2A1 10740:[DB01183 DB12323] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12323|Radotinib ABL1 common genes common pathways GO:0006468| protein phosphorylation ABL1;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;ABL1 GO:0002322| B cell proliferation involved in immune response TLR4;ABL1 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;TLR4 GO:0045087| innate immune response TLR4;ABL1 GO:0043065| positive regulation of apoptotic process CREB1;ABL1 GO:0071222| cellular response to lipopolysaccharide TLR4;ABL1;OPRK1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ABL1;ESR1 10741:[DB01183 DB01840] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process ISYNA1;CYP3A4 10742:[DB01183 DB02358] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02358|LY374571 MTHFD1 common genes common pathways GO:0008152| metabolic process MTHFD1;UGT1A1;CES1 GO:0055114| oxidation-reduction process CYP3A4;MTHFD1;CYP2C8 10743:[DB01183 DB04864] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04864|Huperzine A ACHE common genes common pathways 10744:[DB01183 DB11693] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPP3R1;ESR1;TLR4;CREB1 10745:[DB01183 DB06834] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways GO:0000187| activation of MAPK activity TLR4;SYK GO:0006468| protein phosphorylation CREB1;SYK GO:0002376| immune system process SYK;TLR4 GO:0042742| defense response to bacterium TLR4;SYK GO:0016032| viral reproduction SYK;CREB1 GO:0006954| inflammatory response TLR4;SYK GO:0045087| innate immune response TLR4;SYK 10746:[DB01183 DB07715] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07715|Emodin CSNK2A1;fabZ;AHR common genes common pathways GO:0007165| signal transduction OPRM1;CSNK2A1;OPRD1;ESR1;CREB1;TLR4;OPRK1 GO:0006468| protein phosphorylation CREB1;CSNK2A1 GO:0048511| rhythmic process CSNK2A1;AHR;CREB1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1;AHR GO:0009636| response to toxin CES1;AHR GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;AHR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;TLR4;CREB1;ESR1 GO:0006351| transcription, DNA-dependent AHR;CREB1;CSNK2A1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AHR GO:0045893| positive regulation of transcription, DNA-dependent AHR;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ESR1;AHR;CREB1 10747:[DB01183 DB08691] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08691|ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate CLK1;CLK3 common genes common pathways GO:0006468| protein phosphorylation CLK1;CLK3;CREB1 10748:[DB01183 DB00161] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10;SLCO1A2 GO:0008152| metabolic process UGT1A1;CES1;BCAT1 10749:[DB01183 DB06612] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06612|Mepolizumab IL5 common genes common pathways GO:0030890| positive regulation of B cell proliferation TLR4;IL5 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;IL5;CREB1 GO:0006955| immune response IL5;OPRD1;OPRK1;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL5;ESR1 GO:0006954| inflammatory response TLR4;IL5 10750:[DB01183 DB05152] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05152|NGX267 CHRM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CHRM1;OPRK1 GO:0007165| signal transduction OPRD1;OPRM1;CHRM1;ESR1;OPRK1;TLR4;CREB1 10751:[DB01183 DB01931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways GO:1904646| TLR4;GRIN1 GO:1903428| TLR4;GRIN1 GO:0006811| ion transport GRIN1;SLCO1A2 GO:0008344| adult locomotory behavior OPRD1;GRIN1 GO:0007613| memory GRIN1;CREB1 GO:0043278| response to morphine OPRK1;OPRM1;GRIN1 GO:0008542| visual learning GRIN1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GRIN1;TLR4;CREB1 GO:0043065| positive regulation of apoptotic process GRIN1;CREB1 GO:0019233| sensory perception of pain OPRM1;GRIN1;OPRD1;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN1;OPRM1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;GRIN1 10752:[DB01183 DB04954] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04954|Tecadenoson ADORA1 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA1;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;ADORA1 GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0006954| inflammatory response ADORA1;TLR4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADORA1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADORA1;OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;ADORA1;CREB1;TLR4 GO:0051930| regulation of sensory perception of pain OPRK1;ADORA1;OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation ADORA1;OPRM1 GO:0001666| response to hypoxia ADORA1;CREB1 10753:[DB01183 DB01189] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0006811| ion transport GABRG3;GABRB3;ATP2C1;GABRA1;GABRA4;GABRA6;SLCO1A2;GABRG2;GABRB1;GABRQ;GABRE;GABRA2;GRIA1;KCNA1;GABRP;GLRA1;GABRB2;GABRD;GABRA5;GABRA3;GABRG1 GO:0009636| response to toxin CES1;GABRB1 GO:0014070| response to organic cyclic compound UGT1A1;MT-ND1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0055085| transmembrane transport SLCO1A2;ABCB1;KCNA1 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0070588| calcium ion transmembrane transport OPRM1;ATP2C1 GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0007165| signal transduction GABRP;TLR4;CREB1;GABRD;GABRA5;OPRK1;GRIA1;GABRA6;ESR1;OPRD1;GABRB1;GABRQ;OPRM1;GABRE;GABRB3;ATP2C1 GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport GABRG2;GABRB1;GABRA1;GABRA6;GABRA4;GABRB3;GABRA5;GABRA3;GABRB2;GABRD;ABCB1 GO:0007268| synaptic transmission OPRM1;OPRD1;GABRG2;GABRG1;GABRA5;GABRB2;GABRD;GLRA1;KCNA1;GRIA1;OPRK1 GO:0042493| response to drug GABRG3;ABCB1;UGT1A1;MT-ND1;CREB1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;MT-ND1 GO:1901215| GABRB3;CREB1;GABRB2 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;GLRA1;OPRK1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0071294| cellular response to zinc ion CREB1;GLRA1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GRIA1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;TLR4 10754:[DB01183 DB05110] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05110|VIR201 IFNG common genes common pathways GO:0010628| positive regulation of gene expression TLR4;IFNG GO:0045429| positive regulation of nitric oxide biosynthetic process IFNG;ESR1;OPRM1;TLR4 GO:0032735| positive regulation of interleukin-12 production TLR4;IFNG GO:0032700| negative regulation of interleukin-17 production TLR4;IFNG GO:0006955| immune response OPRK1;TLR4;IFNG;OPRD1 GO:0010629| negative regulation of gene expression CREB1;IFNG;ESR1;OPRD1 GO:0051607| defense response to virus IFNG;OPRK1 GO:0045672| positive regulation of osteoclast differentiation CREB1;IFNG GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;ESR1 GO:0000060| protein import into nucleus, translocation IFNG;OPRD1 10755:[DB01183 DB04307] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04307|5-Hydroxy-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0009636| response to toxin MAOB;CES1 GO:0045471| response to ethanol OPRK1;UGT1A1;MAOB;OPRM1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MAOB;OPRM1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;MAOB GO:0042493| response to drug ABCB1;CREB1;MAOB;UGT1A1 10756:[DB01183 DB04899] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;NPR1;OPRK1 GO:0006468| protein phosphorylation NPR1;CREB1;NPR2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1;NPR3 GO:0007194| negative regulation of adenylate cyclase activity NPR3;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger NPR3;OPRK1;ESR1;OPRM1;OPRD1 GO:0051000| positive regulation of nitric-oxide synthase activity NPR3;ESR1 10757:[DB01183 DB05829] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05829|Parathyroid hormone PTH1R;PTH2R common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;PTH1R;OPRM1;OPRD1;ESR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;PTH1R;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;PTH1R GO:0007165| signal transduction ESR1;PTH1R;OPRM1;OPRD1;OPRK1;PTH2R;CREB1;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;PTH1R GO:0007568| aging CREB1;PTH1R GO:0007186| G-protein coupled receptor signaling pathway OPRM1;PTH1R;OPRD1;PTH2R;OPRK1 10758:[DB01183 DB06194] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06194|Elocalcitol VDR common genes common pathways GO:0007165| signal transduction VDR;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0008285| negative regulation of cell proliferation VDR;OPRM1 GO:0010628| positive regulation of gene expression TLR4;VDR GO:0043401| steroid hormone mediated signaling pathway ESR1;VDR GO:0006351| transcription, DNA-dependent ESR1;VDR;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;ESR1;TLR4;CREB1 GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;VDR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter VDR;ESR1 GO:0007595| lactation VDR;CREB1 10759:[DB01183 DB12116] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;AHR GO:0006355| regulation of transcription, DNA-dependent CREB1;AHR;DNMT1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;ESR1 GO:0006351| transcription, DNA-dependent AHR;CREB1;ESR1;DNMT1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;AHR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;AHR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;ESR1 GO:0009636| response to toxin AHR;CES1 GO:0006366| transcription from RNA polymerase II promoter CREB1;AHR;ESR1 GO:0010628| positive regulation of gene expression DNMT1;TLR4 GO:0048511| rhythmic process AHR;CREB1 10760:[DB01183 DB02104] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;DHFR GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;DHFR 10761:[DB01183 DB05846] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05846|Mito-4509 APP common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;APP;OPRM1;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;APP;OPRM1;OPRD1 GO:0007613| memory CREB1;APP GO:0006468| protein phosphorylation APP;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration APP;ESR1;OPRM1 GO:1900273| CREB1;APP GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TLR4;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;APP GO:0007409| axonogenesis CREB1;APP GO:0008344| adult locomotory behavior OPRD1;APP GO:0000187| activation of MAPK activity TLR4;APP GO:0044267| cellular protein metabolic process APP;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;APP;OPRM1 GO:1904646| TLR4;APP GO:0010628| positive regulation of gene expression TLR4;APP GO:0008285| negative regulation of cell proliferation OPRM1;APP GO:1903223| TLR4;APP GO:0046330| positive regulation of JNK cascade APP;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus APP;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;APP GO:0002576| platelet degranulation APP;ALB GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0050829| defense response to Gram-negative bacterium APP;TLR4 GO:0007626| locomotory behavior OPRM1;OPRK1;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;APP;ESR1 GO:0045087| innate immune response APP;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;ESR1 GO:1990090| APP;CREB1 GO:0010629| negative regulation of gene expression CREB1;APP;ESR1;OPRD1 GO:0007268| synaptic transmission APP;OPRK1;OPRM1;OPRD1 GO:1901215| CREB1;APP GO:0043687| post-translational protein modification ALB;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;APP GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TLR4 GO:0008542| visual learning CREB1;APP 10762:[DB01183 DB02035] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;PPT1 GO:0007268| synaptic transmission OPRK1;OPRM1;OPRD1;PPT1 GO:0043066| negative regulation of apoptotic process PPT1;ALB 10763:[DB01183 DB04891] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04891|Becocalcidiol MED1;VDR common genes common pathways GO:0007165| signal transduction VDR;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0031100| organ regeneration UGT1A1;MED1 GO:0035729| cellular response to hepatocyte growth factor stimulus CREB1;MED1 GO:0008285| negative regulation of cell proliferation VDR;OPRM1 GO:0010628| positive regulation of gene expression MED1;TLR4;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter MED1;ESR1;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;ESR1;MED1;CREB1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1;MED1 GO:0043066| negative regulation of apoptotic process ALB;MED1 GO:0001889| liver development UGT1A1;MED1 GO:0006351| transcription, DNA-dependent VDR;ESR1;MED1;CREB1 GO:0043401| steroid hormone mediated signaling pathway VDR;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter MED1;ESR1 GO:0007595| lactation CREB1;MED1;VDR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;VDR;MED1 GO:0030518| intracellular steroid hormone receptor signaling pathway MED1;ESR1 GO:0006355| regulation of transcription, DNA-dependent MED1;CREB1;VDR;ESR1 GO:0060745| mammary gland branching involved in pregnancy MED1;VDR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;MED1;ESR1 10764:[DB01183 DB00610] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00610|Metaraminol ADRA1A common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ADRA1A;TLR4 GO:0007165| signal transduction OPRK1;ADRA1A;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;OPRK1;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;ADRA1A GO:0007568| aging ADRA1A;CREB1 GO:0042493| response to drug ABCB1;ADRA1A;UGT1A1;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ADRA1A;ESR1;OPRM1;OPRD1 10765:[DB01183 DB02597] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways GO:0019233| sensory perception of pain OPRD1;MME;OPRM1;OPRK1 10766:[DB01183 DB02309] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways GO:0008152| metabolic process UGT1A1;ATIC;CES1 GO:0007626| locomotory behavior OPRM1;OPRK1;HPRT1 GO:0031100| organ regeneration ATIC;UGT1A1 10767:[DB01183 DB13978] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13978|Selisistat SIRT1 common genes common pathways GO:1901215| CREB1;SIRT1 GO:0010629| negative regulation of gene expression CREB1;SIRT1;OPRD1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;SIRT1;ESR1 GO:0016032| viral reproduction SIRT1;CREB1 GO:0045348| positive regulation of MHC class II biosynthetic process SIRT1;TLR4 GO:0006351| transcription, DNA-dependent ESR1;SIRT1;CREB1 GO:0007623| circadian rhythm SIRT1;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade SIRT1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter SIRT1;ESR1 GO:0042981| regulation of apoptotic process SIRT1;CREB1;ESR1 GO:0043065| positive regulation of apoptotic process SIRT1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;SIRT1 GO:0043066| negative regulation of apoptotic process SIRT1;ALB GO:0006366| transcription from RNA polymerase II promoter ESR1;SIRT1;CREB1 GO:0032868| response to insulin stimulus SIRT1;OPRK1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;SIRT1 GO:0048511| rhythmic process SIRT1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity SIRT1;ESR1 GO:1990830| SIRT1;CREB1 GO:0030154| cell differentiation CREB1;SIRT1 GO:0071456| cellular response to hypoxia OPRD1;SIRT1 GO:0009267| cellular response to starvation ALB;SIRT1 10768:[DB01183 DB02547] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 10769:[DB01183 DB06429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06429|Talnetant TACR3 common genes common pathways GO:0043278| response to morphine OPRK1;OPRM1;TACR3 GO:0007186| G-protein coupled receptor signaling pathway TACR3;OPRD1;OPRM1;OPRK1 GO:0032355| response to estradiol stimulus TACR3;ESR1 GO:0007568| aging CREB1;TACR3 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;TACR3 GO:0042220| response to cocaine TACR3;OPRM1;OPRK1 10770:[DB01183 DB04932] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0032755| positive regulation of interleukin-6 production ADORA2B;TLR4 GO:0032722| positive regulation of chemokine production ADORA2B;TLR4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;ADORA2B;ADORA2A;TLR4;CREB1;ADORA1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ADORA2B;OPRK1;ADORA1;ADORA2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADORA1;OPRK1 GO:0001666| response to hypoxia ADORA1;CREB1 GO:0008285| negative regulation of cell proliferation ADORA1;ADORA2A;OPRM1 GO:0042755| eating behavior OPRK1;ADORA2A;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADORA1;OPRK1 GO:0044267| cellular protein metabolic process ALB;ADORA2B;ADORA2A GO:0000187| activation of MAPK activity TLR4;ADORA2B GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1 GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0007626| locomotory behavior OPRM1;ADORA2A;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA2A;ADORA1;OPRM1 GO:0097190| apoptotic signaling pathway TLR4;ADORA1 GO:0006954| inflammatory response TLR4;ADORA2A;ADORA1 GO:0007600| sensory perception OPRK1;ADORA2A;OPRM1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ADORA2A GO:0042493| response to drug ABCB1;CREB1;ADORA2A;UGT1A1 10771:[DB01183 DB00644] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GNRHR;GNRHR2;OPRD1;OPRM1 GO:0007165| signal transduction TLR4;CREB1;GNRHR2;OPRK1;GNRHR;OPRD1;OPRM1;ESR1 10772:[DB01183 DB04927] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04927|NM100060 SQLE common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;SQLE GO:0006695| cholesterol biosynthetic process CES1;SQLE GO:0010033| response to organic substance CREB1;UGT1A1;SQLE 10773:[DB01183 DB14543] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes SLCO1A2;CYP2C8;ABCB1;CYP3A4 common pathways GO:0015711| organic anion transport SLCO1A2 GO:0097267| CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction OPRM1;OPRD1;NR3C1;ESR1;ANXA1;OPRK1;CREB1;TLR4 GO:0048545| response to steroid hormone stimulus UGT1A1;HSD11B2 GO:0032870| cellular response to hormone stimulus CYP11B1;CYP11B2;UGT1A1 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP3A4 GO:0044849| OPRM1;OPRK1;ANXA1 GO:0002376| immune system process ANXA1;TLR4 GO:0006810| transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP11B1;CYP11B2;CYP3A7;CYP3A4;UGT1A1;CYP2C8;CYP3A5 GO:0045332| phospholipid translocation ABCB1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;ALB GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;ANXA1;OPRK1 GO:0072089| stem cell proliferation ABCB1 GO:0032355| response to estradiol stimulus ESR1;ANXA1 GO:0051384| response to glucocorticoid stimulus UGT1A1;ANXA1;HSD11B2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ANXA1;OPRM1;OPRD1 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0001666| response to hypoxia HSD11B2;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1;ABCG2 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter CREB1;NR3C1;ESR1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0032868| response to insulin stimulus OPRK1;HSD11B2 GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0009636| response to toxin SLC22A8;CES1 GO:0002933| CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4 GO:0006082| organic acid metabolic process CYP2C8 GO:0045087| innate immune response TLR4;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0043066| negative regulation of apoptotic process ALB;ANXA1 GO:0019373| epoxygenase P450 pathway CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP3A7;CYP2C8;CYP3A5 GO:0008152| metabolic process HSD3B1;UGT1A1;CES1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NR3C1;ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4;ANXA1 GO:0043065| positive regulation of apoptotic process CREB1;ANXA1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:1901529| ABCB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0006955| immune response CYP11B1;OPRD1;OPRK1;TLR4 GO:0006954| inflammatory response ANXA1;TLR4 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;ANXA1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP11B1;CYP11B2;CYP3A7;CYP2C8;CYP3A5;HSD11B2;HSD3B1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0032094| response to food HSD11B2;OPRM1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;HSD11B2;ABCG2;ANXA1 10774:[DB01183 DB07641] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;MAOA;CYP3A4 10775:[DB01183 DB04235] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0048148| behavioral response to cocaine OPRK1;ABAT GO:0007626| locomotory behavior ABAT;OPRK1;OPRM1 GO:0045471| response to ethanol ABAT;OPRK1;UGT1A1;OPRM1 GO:0035094| response to nicotine CREB1;ABAT GO:0042493| response to drug ABCB1;ABAT;UGT1A1;CREB1 GO:0007568| aging CREB1;ABAT GO:0001666| response to hypoxia ABAT;CREB1 GO:0042220| response to cocaine OPRK1;ABAT;OPRM1 10776:[DB01183 DB00389] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP19A1;TPO GO:0060065| uterus development CYP19A1;ESR1 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0098869| ALB;TPO 10777:[DB01183 DB01164] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01164|Calcium Chloride S100A13 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;S100A13 10778:[DB01183 DB06678] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0007626| locomotory behavior OPRK1;HTR2C;OPRM1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CES1;CYP3A4 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;HRH1;OPRD1;HTR2B;HTR2C;OPRK1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HTR2B GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HTR2B GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0006954| inflammatory response TLR4;HRH1 GO:0016032| viral reproduction CREB1;HTR2A GO:0008542| visual learning HRH1;CREB1 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;OPRK1;HTR2C GO:0042493| response to drug ABCB1;HTR2C;HTR2B;UGT1A1;CREB1;HTR2A GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP3A4 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP3A4 GO:0007610| behavior HTR2A;HTR2B;HTR2C;OPRK1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;HTR2B;HTR2C;ADRA2A;OPRD1;HRH1;OPRM1;HTR2A;ADRA2B;ADRA2C;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;HRH1;ADRA2C;ADRA2B;HTR2A;HTR2C;HTR2B;ADRA2A;OPRK1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4 GO:0007613| memory HTR2A;HRH1;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1 GO:0007568| aging CREB1;HTR2A GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1;HTR2C GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0051930| regulation of sensory perception of pain ADRA2C;OPRD1;OPRM1;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;HTR2B;HTR2C;TLR4 GO:0000187| activation of MAPK activity TLR4;ADRA2B 10779:[DB01183 DB08703] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways GO:0006468| protein phosphorylation MAP3K9;CREB1 GO:0006351| transcription, DNA-dependent CREB1;MAP3K9;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;MAP3K9 GO:0006355| regulation of transcription, DNA-dependent MAP3K9;ESR1;CREB1 10780:[DB01183 DB09283] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0043066| negative regulation of apoptotic process PDE3A;ALB GO:0071560| cellular response to transforming growth factor beta stimulus PDE2A;PDE3A;CREB1 GO:0008152| metabolic process PDE11A;PDE2A;PDE5A;UGT1A1;PDE10A;CES1 GO:0071222| cellular response to lipopolysaccharide PDE4D;TLR4;OPRK1;PDE4B GO:0007626| locomotory behavior OPRM1;PDE1B;OPRK1 GO:0071260| cellular response to mechanical stimulus TLR4;PDE2A GO:0006629| lipid metabolic process PDE3A;CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;ESR1 GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4;PDE4B GO:0008542| visual learning CREB1;PDE1B GO:0043951| negative regulation of cAMP-mediated signaling PDE3B;OPRM1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PDE8A GO:0007268| synaptic transmission OPRM1;OPRD1;PDE7B;OPRK1 GO:0042493| response to drug PDE3A;UGT1A1;CREB1;ABCB1 GO:0070588| calcium ion transmembrane transport PDE2A;OPRM1 GO:0007165| signal transduction PDE11A;PDE7A;OPRK1;PDE9A;PDE4B;PDE4C;PDE6C;PDE7B;PDE1C;TLR4;PDE6B;CREB1;PDE2A;PDE5A;PDE8A;PDE3A;PDE1A;PDE10A;PDE8B;PDE3B;PDE6A;PDE1B;ESR1;PDE4A;OPRD1;PDE4D;OPRM1 GO:0050729| positive regulation of inflammatory response PDE2A;TLR4 GO:0007186| G-protein coupled receptor signaling pathway PDE4A;OPRD1;PDE4D;OPRM1;PDE3B;PDE1B;PDE1A;PDE10A;PDE8B;PDE2A;PDE8A;PDE3A;PDE7A;PDE11A;OPRK1;PDE4B;PDE4C;PDE7B GO:0007568| aging PDE4D;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;PDE8A;TLR4 10781:[DB01183 DB00740] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1;CYP1A1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0007568| aging CYP1A1;CREB1 GO:0006810| transport ABCG2;ABCB1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;UGT1A1;CYP2C8 GO:0097267| CYP1A2;CYP2C8;CYP1A1 GO:0006811| ion transport SCN5A;SLCO1A2 GO:0002933| CYP2C8;CYP1A1;CYP3A4 GO:0009636| response to toxin CES1;SLC7A11;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0055085| transmembrane transport SCN5A;SLCO1A2;ABCB1;ABCG2 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0010033| response to organic substance CREB1;CYP1A1;UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CYP1A1;TLR4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0001889| liver development CYP1A1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8;CYP1A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042493| response to drug CREB1;CYP1A1;UGT1A1;ABCG2;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0032094| response to food OPRM1;CYP1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A1;CYP1A2;CYP3A4 GO:0035094| response to nicotine CREB1;SLC7A11 10782:[DB01183 DB06941] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06941|(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide S100B common genes common pathways GO:0007409| axonogenesis CREB1;S100B GO:0071456| cellular response to hypoxia OPRD1;S100B GO:0007613| memory CREB1;S100B GO:0051384| response to glucocorticoid stimulus UGT1A1;S100B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;TLR4 GO:0045087| innate immune response S100B;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;S100B 10783:[DB01183 DB07268] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07268|2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE MAPK8 common genes common pathways GO:0010628| positive regulation of gene expression MAPK8;TLR4 GO:0048511| rhythmic process MAPK8;CREB1 GO:0006468| protein phosphorylation MAPK8;CREB1 GO:0042752| regulation of circadian rhythm MAPK8;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;MAPK8 GO:0043065| positive regulation of apoptotic process CREB1;MAPK8 GO:0043066| negative regulation of apoptotic process ALB;MAPK8 GO:0071260| cellular response to mechanical stimulus TLR4;MAPK8 10784:[DB01183 DB01482] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 10785:[DB01183 DB01297] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01297|Practolol ADRB1;CYP2D6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB1;OPRD1;OPRM1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;ADRB1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CES1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A4 10786:[DB01183 DB11772] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11772|Pilaralisib PIK3CA common genes common pathways GO:0007411| axon guidance PIK3CA;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;PIK3CA GO:0006468| protein phosphorylation CREB1;PIK3CA GO:0033138| positive regulation of peptidyl-serine phosphorylation PIK3CA;OPRD1 GO:0043491| protein kinase B signaling cascade PIK3CA;CREB1 GO:0006954| inflammatory response TLR4;PIK3CA GO:0001889| liver development PIK3CA;UGT1A1 GO:0045087| innate immune response PIK3CA;TLR4 10787:[DB01183 DB02095] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02095|Isatin MAOB;MAOB common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1;MAOB;OPRM1 GO:0032496| response to lipopolysaccharide TLR4;MAOB;UGT1A1;OPRM1 GO:0055114| oxidation-reduction process MAOB;CYP2C8;CYP3A4 GO:0042493| response to drug CREB1;MAOB;UGT1A1;ABCB1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0009636| response to toxin MAOB;CES1 10788:[DB01183 DB09568] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process HSD17B10;CYP3A4;HADH;CYP3A7;CYP3A43;CYP2C8;CYP3A5;CYP4F2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;LPL;CREB1;UGT1A1;HADH GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process HSD17B10;CYP3A4;HADH;LPL;ECHS1;ELOVL4;DGAT2 GO:0019373| epoxygenase P450 pathway CYP4F2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CES1;CYP3A5;CYP2C8 GO:0008152| metabolic process CES1;UGT1A1;ECHS1 GO:0036378| CYP3A4 GO:0032868| response to insulin stimulus HADH;OPRK1 GO:0002933| CYP3A4;CYP3A7;CYP2C8;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0014823| response to activity HADH;CREB1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;UGT1A1;CYP3A5;CYP2C8 GO:0050729| positive regulation of inflammatory response LPL;TLR4 GO:0097267| CYP4F2;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP4F2;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 10789:[DB01183 DB11994] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes CYP3A4 common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1H3;NR1H2 GO:0042752| regulation of circadian rhythm CREB1;NR1H3 GO:0006954| inflammatory response ALOX5;TLR4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2D6;CYP2C9;ALOX5;CYP3A43;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2;CYP2E1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;NR1H2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8;CYP2C9 GO:0006355| regulation of transcription, DNA-dependent NR1H3;NR1H2;CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;NR1H2;NR1H3;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR1H2;NR1H3 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;CREB1;TLR4;NR1H2;ESR1 GO:0071222| cellular response to lipopolysaccharide TLR4;NR1H3;OPRK1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C8;CYP3A7;CYP1A2;CYP3A4;CYP2E1;CES1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C8;CYP2C9 GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0043401| steroid hormone mediated signaling pathway NR1H2;NR1H3;ESR1 GO:0006351| transcription, DNA-dependent CREB1;NR1H2;NR1H3;ESR1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP1A2;CYP3A4;CYP2E1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR1H2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0010628| positive regulation of gene expression TLR4;NR1H2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP3A5;CYP2C8 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1;CYP2C9;CYP2D6;CYP2C8 GO:0097267| CYP1A2;CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2C8;CYP2D6;CYP2C9 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C9;UGT1A1;CYP2C8;CYP2D6;CYP3A5 10790:[DB01183 DB05903] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05903|KOS-1584 CYP3A4 common genes CYP3A4 common pathways GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 10791:[DB01183 DB00491] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways GO:0007626| locomotory behavior OPRK1;OPRM1;GAA GO:0008152| metabolic process AMY2A;MGAM;GANAB;GAA;CES1;GANC;UGT1A1 10792:[DB01183 DB04556] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways 10793:[DB01183 DB06436] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06436|Semaxanib KDR;PTGS2 common genes common pathways GO:0010033| response to organic substance PTGS2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;KDR;TLR4 GO:0098869| ALB;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0030154| cell differentiation CREB1;KDR GO:0006468| protein phosphorylation CREB1;KDR GO:0007613| memory CREB1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0007568| aging CREB1;PTGS2 GO:0006954| inflammatory response TLR4;PTGS2 GO:0016032| viral reproduction CREB1;KDR GO:0042493| response to drug UGT1A1;CREB1;ABCB1;PTGS2 GO:0010629| negative regulation of gene expression CREB1;KDR;ESR1;OPRD1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS2 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0043066| negative regulation of apoptotic process PTGS2;KDR;ALB GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;TLR4;UGT1A1 GO:0019233| sensory perception of pain OPRK1;PTGS2;OPRM1;OPRD1 10794:[DB01183 DB04970] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04970|Lesopitron HTR1A common genes common pathways GO:0007610| behavior HTR1A;OPRK1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;HTR1A;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR1A;OPRD1;OPRM1 10795:[DB01183 DB00335] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB11;ABCB1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0015721| bile acid and bile salt transport ALB;ABCB11;SLCO1A2 GO:1904646| TLR4;ADRB2 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1;ABCB11 GO:0072089| stem cell proliferation ABCB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRB1;ADRB2;OPRM1;OPRD1 GO:0045332| phospholipid translocation ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0007165| signal transduction ADRB1;OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;ADRB2 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0099040| ABCB1 GO:0042493| response to drug CREB1;UGT1A1;ABCB1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:1901529| ABCB1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CES1;CYP3A4 10796:[DB01183 DB06867] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways GO:0050821| protein stabilization CREB1;PIN1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;PIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PIN1;CREB1;TLR4;ESR1 10797:[DB01183 DB07412] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10798:[DB01183 DB02710] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02710|2,3,-Dihydroxybenzoylserine LCN2 common genes common pathways GO:0006811| ion transport LCN2;SLCO1A2 GO:0002376| immune system process TLR4;LCN2 GO:0045087| innate immune response TLR4;LCN2 10799:[DB01183 DB01681] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways GO:0008152| metabolic process PGAM2;UGT1A1;CES1 10800:[DB01183 DB08492] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways GO:0042060| wound healing OPRM1;ALOX15 GO:0006629| lipid metabolic process ALOX15;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;ALOX15 GO:0006954| inflammatory response ALOX15;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ALOX15;TLR4 10801:[DB01183 DB02504] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02504|[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid PLA2G2A common genes common pathways GO:0050729| positive regulation of inflammatory response TLR4;PLA2G2A GO:0070374| positive regulation of ERK1 and ERK2 cascade PLA2G2A;TLR4;OPRM1 GO:0006629| lipid metabolic process CYP3A4;PLA2G2A 10802:[DB01183 DB07076] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07076|6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE PLAU common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;PLAU;OPRK1;CREB1;TLR4 GO:0001666| response to hypoxia PLAU;CREB1 10803:[DB01183 DB00015] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0043687| post-translational protein modification FGA;ALB GO:0007623| circadian rhythm SERPINE1;CREB1 GO:0043066| negative regulation of apoptotic process PLAUR;ALB GO:0002576| platelet degranulation FGA;ALB;PLG;SERPINE1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;ESR1;TLR4;CREB1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;SERPINE1 GO:0050829| defense response to Gram-negative bacterium TLR4;SERPINE1 GO:0045087| innate immune response TLR4;FGA GO:0044267| cellular protein metabolic process FGA;ALB;PLG GO:0070374| positive regulation of ERK1 and ERK2 cascade FGA;TLR4;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;PLG GO:0050729| positive regulation of inflammatory response SERPINE1;TLR4 GO:0002224| toll-like receptor signaling pathway FGA;TLR4 GO:0002376| immune system process TLR4;FGA GO:0032757| positive regulation of interleukin-8 production TLR4;SERPINE1 GO:0007165| signal transduction OPRK1;FGA;PLAUR;CREB1;TLR4;ESR1;OPRM1;OPRD1 10804:[DB01183 DB08651] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways GO:0007409| axonogenesis TOP2B;CREB1 10805:[DB01183 DB07271] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 10806:[DB01183 DB00752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes CYP3A4 common pathways GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2A6;CYP1A2;CYP2C9;UGT1A1;CYP2D6;CYP2C8;CYP2C19 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8;CYP2D6;CYP2C9 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0097267| CYP1A2;CYP2C8;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2C9;UGT1A1;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP2A6;CYP1A2 GO:0002933| CYP2C8;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0009636| response to toxin MAOB;CES1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;TLR4;UGT1A1;MAOB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1;UGT1A1;MAOB GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CES1;CYP2C8;CYP2C19;CYP2D6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9;CYP1A2;CYP2E1;CYP2A6 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;CREB1;MAOB;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP2A6;CYP3A4;CYP2C9;CYP2C19;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2A6;CYP1A2;MAOA;CYP2C9;MAOB;CYP2D6;CYP2C19;CYP2C8 10807:[DB01183 DB09013] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0007165| signal transduction ADRB2;ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1;ADRB1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2D6;CYP2C8 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;OPRK1;OPRD1;OPRM1;ADRB2 GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CES1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;ADRB2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 10808:[DB01183 DB06856] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06856|6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE PLAU common genes common pathways GO:0007165| signal transduction PLAU;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0001666| response to hypoxia CREB1;PLAU 10809:[DB01183 DB04612] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04612|N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;XIAP GO:0050727| regulation of inflammatory response XIAP;ESR1;TLR4 10810:[DB01183 DB03181] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TLR4;CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;THRB GO:0043401| steroid hormone mediated signaling pathway ESR1;THRB GO:0006351| transcription, DNA-dependent ESR1;CREB1;THRB GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;THRB GO:0060509| Type I pneumocyte differentiation CREB1;THRB GO:0006355| regulation of transcription, DNA-dependent ESR1;THRB;CREB1 10811:[DB01183 DB09302] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09302|Alirocumab PCSK9 common genes common pathways GO:0043687| post-translational protein modification PCSK9;ALB GO:0006629| lipid metabolic process PCSK9;CYP3A4 GO:0001889| liver development UGT1A1;PCSK9 GO:0044267| cellular protein metabolic process ALB;PCSK9 GO:0008202| steroid metabolic process CYP3A4;PCSK9;UGT1A1;CYP2C8 GO:0009267| cellular response to starvation PCSK9;ALB 10812:[DB01183 DB03906] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0035094| response to nicotine CREB1;HMOX1 GO:0055114| oxidation-reduction process CYP2C8;HMOX1;CYP3A4 GO:0043065| positive regulation of apoptotic process CREB1;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;HMOX1 GO:0001666| response to hypoxia CREB1;HMOX1 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HMOX1 GO:0043627| response to estrogen stimulus OPRK1;ESR1;HMOX1 GO:0042167| heme catabolic process HMOX1;UGT1A1 GO:0071456| cellular response to hypoxia OPRD1;HMOX1 10813:[DB01183 DB13044] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13044|Gossypol BCL2L1 common genes common pathways GO:0051881| regulation of mitochondrial membrane potential OPRD1;BCL2L1 GO:0008584| male gonad development BCL2L1;ESR1 GO:0042981| regulation of apoptotic process BCL2L1;CREB1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;BCL2L1 GO:0043065| positive regulation of apoptotic process BCL2L1;CREB1 GO:0009314| response to radiation OPRM1;BCL2L1;OPRK1 10814:[DB01183 DB12789] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12789|Dinoprost PTGDR2 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;PTGDR2 GO:0007165| signal transduction PTGDR2;OPRM1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;PTGDR2;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PTGDR2;OPRK1 GO:0006955| immune response OPRD1;PTGDR2;TLR4;OPRK1 GO:0007268| synaptic transmission OPRK1;PTGDR2;OPRM1;OPRD1 GO:0007218| neuropeptide signaling pathway OPRK1;OPRM1;OPRD1;PTGDR2 10815:[DB01183 DB01852] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01852|Kaempherol UGT3A1 common genes common pathways GO:0008152| metabolic process CES1;UGT1A1;UGT3A1 10816:[DB01183 DB02235] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02235|L-methionine (R)-S-oxide APP common genes common pathways GO:0007613| memory CREB1;APP GO:0006468| protein phosphorylation CREB1;APP GO:0007204| elevation of cytosolic calcium ion concentration APP;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1;APP GO:0007186| G-protein coupled receptor signaling pathway APP;OPRK1;OPRD1;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1 GO:1900273| APP;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;APP;ESR1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;TLR4;OPRM1 GO:0008344| adult locomotory behavior OPRD1;APP GO:0000187| activation of MAPK activity APP;TLR4 GO:0044267| cellular protein metabolic process APP;ALB GO:0007409| axonogenesis APP;CREB1 GO:0008285| negative regulation of cell proliferation APP;OPRM1 GO:1903223| TLR4;APP GO:1904646| APP;TLR4 GO:0010628| positive regulation of gene expression APP;TLR4 GO:0046330| positive regulation of JNK cascade TLR4;APP GO:0045087| innate immune response APP;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;APP GO:1990090| APP;CREB1 GO:0002576| platelet degranulation APP;ALB GO:0043065| positive regulation of apoptotic process APP;CREB1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0007626| locomotory behavior OPRK1;APP;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;APP;ESR1 GO:0042346| positive regulation of NF-kappaB import into nucleus APP;TLR4 GO:1901215| APP;CREB1 GO:0043687| post-translational protein modification ALB;APP GO:0010629| negative regulation of gene expression CREB1;APP;ESR1;OPRD1 GO:0007268| synaptic transmission OPRM1;OPRD1;APP;OPRK1 GO:0008542| visual learning APP;CREB1 GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;APP 10817:[DB01183 DB03551] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways GO:0042493| response to drug ABCB1;CREB1;PNP;UGT1A1 GO:0006955| immune response OPRD1;OPRK1;PNP;TLR4 10818:[DB01183 DB04043] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04043|Carboxymycobactin T LCN2 common genes common pathways GO:0045087| innate immune response TLR4;LCN2 GO:0006811| ion transport SLCO1A2;LCN2 GO:0002376| immune system process LCN2;TLR4 10819:[DB01183 DB13940] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13940|2,5-Dimethoxy-4-ethylthioamphetamine HTR2A;HTR2C common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2C;OPRK1;ESR1;HTR2A;OPRM1;OPRD1 GO:0019233| sensory perception of pain HTR2A;OPRM1;OPRD1;OPRK1 GO:0007626| locomotory behavior OPRM1;OPRK1;HTR2C GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0042493| response to drug HTR2A;UGT1A1;CREB1;ABCB1;HTR2C GO:0007268| synaptic transmission HTR2C;OPRK1;OPRM1;OPRD1;HTR2A GO:0016032| viral reproduction CREB1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1 GO:0007613| memory HTR2A;CREB1 GO:0007568| aging CREB1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;HTR2A;OPRK1;HTR2C GO:0007165| signal transduction ESR1;HTR2A;OPRM1;OPRD1;HTR2C;OPRK1;CREB1;TLR4 GO:0007610| behavior HTR2A;HTR2C;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;HTR2C;OPRM1;HTR2A GO:0045600| positive regulation of fat cell differentiation HTR2C;CREB1;HTR2A 10820:[DB01183 DB05073] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05073|SRT501 SIRT1 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;ESR1;SIRT1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;SIRT1;CREB1 GO:1901215| SIRT1;CREB1 GO:0016032| viral reproduction SIRT1;CREB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade SIRT1;ESR1 GO:0007623| circadian rhythm SIRT1;CREB1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;SIRT1 GO:0045348| positive regulation of MHC class II biosynthetic process TLR4;SIRT1 GO:0043066| negative regulation of apoptotic process ALB;SIRT1 GO:0043065| positive regulation of apoptotic process SIRT1;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SIRT1;TLR4;CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter SIRT1;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1;SIRT1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;SIRT1 GO:0032868| response to insulin stimulus OPRK1;SIRT1 GO:0006366| transcription from RNA polymerase II promoter CREB1;SIRT1;ESR1 GO:1990830| CREB1;SIRT1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;SIRT1 GO:0048511| rhythmic process SIRT1;CREB1 GO:0009267| cellular response to starvation ALB;SIRT1 GO:0030154| cell differentiation SIRT1;CREB1 GO:0071456| cellular response to hypoxia SIRT1;OPRD1 10821:[DB01183 DB07950] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07950|Indoleacetic acid PLA2G2E;SKP1;CCBL1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle SKP1;ABCB1 GO:0043687| post-translational protein modification ALB;SKP1 GO:0006954| inflammatory response TLR4;PLA2G2E GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 10822:[DB01183 DB05010] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways GO:0007194| negative regulation of adenylate cyclase activity GABBR2;OPRM1;GABBR1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;GABBR2 GO:0007165| signal transduction TLR4;CREB1;OPRK1;GABBR2;ESR1;OPRD1;GABBR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway GABBR2;OPRK1;OPRM1;GABBR1;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;GABBR1;OPRD1;OPRK1 10823:[DB01183 DB05374] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05374|Rindopepimut EGFR common genes common pathways GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;EGFR;TLR4 GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;EGFR GO:0050729| positive regulation of inflammatory response EGFR;TLR4 GO:0006468| protein phosphorylation EGFR;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;EGFR;OPRK1;CREB1;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1 GO:0007623| circadian rhythm CREB1;EGFR GO:0042060| wound healing EGFR;OPRM1 GO:0001889| liver development EGFR;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;EGFR GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 10824:[DB01183 DB00089] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00089|Capromab pendetide FOLH1 common genes common pathways GO:0008152| metabolic process CES1;FOLH1;UGT1A1 10825:[DB01183 DB04583] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0042594| response to starvation DHODH;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;DHODH GO:0055114| oxidation-reduction process DHODH;CYP3A4;CYP2C8 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;DHODH GO:0007595| lactation DHODH;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;DHODH 10826:[DB01183 DB01675] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;ACAD8;CREB1 GO:0006629| lipid metabolic process CYP3A4;ACAD8 GO:0008152| metabolic process CES1;ACAD8;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;ACAD8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ACAD8;ESR1 10827:[DB01183 DB09326] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09326|Ammonia N-13 NAGS;RHCG common genes common pathways GO:0030855| epithelial cell differentiation RHCG;CES1 10828:[DB01183 DB07457] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways GO:0006468| protein phosphorylation PDPK1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PDPK1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PDPK1;CREB1 10829:[DB01183 DB07970] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways GO:0043065| positive regulation of apoptotic process EPHA7;CREB1 GO:0006468| protein phosphorylation CREB1;EPHA7 10830:[DB01183 DB07844] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07844|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways 10831:[DB01183 DB07051] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;PDE4D;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway PDE4D;OPRD1;OPRM1;OPRK1 GO:0007568| aging CREB1;PDE4D GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;PDE4D GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4 10832:[DB01183 DB08207] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR GO:0006810| transport ABCB1;TTR 10833:[DB01183 DB00086] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00086|Streptokinase PLG;F2R;PLA2G4A common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent F2R;ESR1;CREB1 GO:0006954| inflammatory response TLR4;F2R GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;F2R;OPRD1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade F2R;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;F2R;UGT1A1;TLR4 GO:0006629| lipid metabolic process CYP3A4;PLA2G4A GO:0002576| platelet degranulation PLG;ALB GO:0008152| metabolic process PLA2G4A;UGT1A1;CES1 GO:0070374| positive regulation of ERK1 and ERK2 cascade F2R;OPRM1;TLR4 GO:0044267| cellular protein metabolic process PLG;ALB GO:0051930| regulation of sensory perception of pain F2R;OPRM1;OPRD1;OPRK1 GO:0008285| negative regulation of cell proliferation PLG;OPRM1;F2R GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;F2R GO:0007186| G-protein coupled receptor signaling pathway F2R;OPRD1;OPRM1;OPRK1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;F2R;OPRD1;OPRM1 10834:[DB01183 DB13995] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13995|Ferric pyrophosphate citrate FTL;FTH1;HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB GO:0098869| HBA1;HBB;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;HBB;OPRM1;ESR1 GO:0008285| negative regulation of cell proliferation FTH1;OPRM1 GO:0006955| immune response TLR4;OPRK1;OPRD1;FTH1 GO:0055114| oxidation-reduction process CYP3A4;FTH1;CYP2C8 10835:[DB01183 DB06795] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06795|Mafenide CA6 common genes common pathways 10836:[DB01183 DB05854] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05854|CLX-0921 PPARG common genes common pathways GO:0031100| organ regeneration UGT1A1;PPARG GO:0007165| signal transduction TLR4;CREB1;PPARG;OPRK1;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PPARG;OPRK1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0048511| rhythmic process CREB1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;ESR1 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0042493| response to drug CREB1;PPARG;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 10837:[DB01183 DB00986] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway CHRM1;CHRM2;OPRM1;OPRD1;CHRM3;OPRK1 GO:0007165| signal transduction OPRD1;OPRM1;CHRM2;CHRM1;ESR1;CHRM3;TLR4;CREB1;OPRK1 10838:[DB01183 DB05443] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05443|ADL 10-0101 OPRK1 common genes OPRK1 common pathways GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:1900745| OPRK1 GO:0033603| positive regulation of dopamine secretion OPRK1 GO:1903715| OPRK1 GO:0048148| behavioral response to cocaine OPRK1 GO:0007626| locomotory behavior OPRK1;OPRM1 GO:0009314| response to radiation OPRK1;OPRM1 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4 GO:0040017| positive regulation of locomotion OPRK1 GO:2000505| regulation of energy homeostasis OPRK1 GO:0051607| defense response to virus OPRK1 GO:0007268| synaptic transmission OPRK1;OPRD1;OPRM1 GO:0007600| sensory perception OPRK1;OPRM1 GO:0043278| response to morphine OPRM1;OPRK1 GO:1903937| OPRK1 GO:0006955| immune response OPRD1;OPRK1;TLR4 GO:0042711| maternal behavior OPRK1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:1901381| OPRK1 GO:0050951| sensory perception of temperature stimulus OPRK1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0007610| behavior OPRK1 GO:1990708| OPRK1 GO:0044849| OPRK1;OPRM1 GO:0042220| response to cocaine OPRM1;OPRK1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0032868| response to insulin stimulus OPRK1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0046877| regulation of saliva secretion OPRK1 GO:0033685| negative regulation of luteinizing hormone secretion OPRK1 10839:[DB01183 DB05098] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05098|Leptin LEPR common genes common pathways GO:2000505| regulation of energy homeostasis LEPR;OPRK1 10840:[DB01183 DB00217] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;ADRB3;OPRK1;ADRA2A;OPRD1;OPRM1;ADRB2;ADRA2B;ADRA2C GO:0007568| aging ADRB3;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A;OPRK1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB GO:0007165| signal transduction OPRD1;OPRM1;ADRA2B;ADRB2;ADRA2C;ESR1;ADRB1;OPRK1;ADRB3;ADRA2A;TLR4;CREB1 GO:0042755| eating behavior OPRD1;OPRM1;ADRB3;OPRK1 GO:0006811| ion transport KCNJ1;SLCO1A2 GO:0051930| regulation of sensory perception of pain ADRA2C;OPRD1;OPRM1;OPRK1 GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:1904646| TLR4;ADRB2 GO:0016579| protein deubiquitination ESR1;ADRB2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ADRB3;OPRM1;OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 10841:[DB01183 DB12202] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12202|Zalutumumab EGFR common genes common pathways GO:0001889| liver development UGT1A1;EGFR GO:0042060| wound healing OPRM1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;ESR1 GO:0007623| circadian rhythm CREB1;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;EGFR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CREB1;ESR1 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1;ESR1 GO:0006468| protein phosphorylation EGFR;CREB1 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0071363| cellular response to growth factor stimulus EGFR;CREB1;OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;EGFR;OPRK1;CREB1;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;EGFR;OPRM1 GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 10842:[DB01183 DB01090] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways GO:0070588| calcium ion transmembrane transport CHRNA10;OPRM1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CHRNA3;CHRNA10;OPRK1;CREB1;CHRNB4;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;OPRM1;ESR1 GO:0006811| ion transport CHRNA3;CHRNA10;CHRNB4;SLCO1A2 GO:0007626| locomotory behavior CHRNB4;OPRK1;CHRNA3;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNB4;CHRNA10;CHRNA3;OPRM1 GO:0035094| response to nicotine CHRNB4;CREB1 10843:[DB01183 DB12140] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;TLR4;TNF GO:0046330| positive regulation of JNK cascade TNF;TLR4;IL1B GO:0032496| response to lipopolysaccharide IL1B;UGT1A1;TLR4;OPRM1 GO:0032729| positive regulation of interferon-gamma production TNF;TLR4;IL1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:1900745| OPRK1;IL1B GO:0071260| cellular response to mechanical stimulus IL1B;TLR4 GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0050727| regulation of inflammatory response ESR1;TLR4;TNF GO:0043065| positive regulation of apoptotic process CREB1;TNF;IL6 GO:0050829| defense response to Gram-negative bacterium IL6;TLR4 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;IL6;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TNF;TLR4;IL6;IL1B;ESR1 GO:0042346| positive regulation of NF-kappaB import into nucleus IL1B;TLR4;TNF GO:0043066| negative regulation of apoptotic process ALB;IL6 GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4;IL1B GO:0043491| protein kinase B signaling cascade CREB1;TNF;IL1B GO:0043687| post-translational protein modification ALB;IL6 GO:0042742| defense response to bacterium TLR4;TNF GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;TNF GO:0051607| defense response to virus IL6;OPRK1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;TNF;IL6;IL1B;ESR1 GO:0006953| acute-phase response IL6;UGT1A1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TLR4;IL6;IL1B GO:0006954| inflammatory response TNF;TLR4;IL6;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;IL1B;IL6;TNF GO:0006955| immune response OPRD1;TNF;TLR4;IL6;IL1B;OPRK1 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1;IL6 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;IL1B;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;IL6;OPRD1 GO:0032722| positive regulation of chemokine production IL6;TLR4;TNF GO:0032757| positive regulation of interleukin-8 production IL1B;TLR4;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TLR4;IL1B;OPRM1;ESR1 GO:0032755| positive regulation of interleukin-6 production IL6;IL1B;TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;TNF GO:0000187| activation of MAPK activity IL1B;TLR4;TNF GO:0044267| cellular protein metabolic process IL6;ALB GO:0008285| negative regulation of cell proliferation IL6;IL1B;OPRM1 GO:0010033| response to organic substance CREB1;TNF;UGT1A1 GO:0010628| positive regulation of gene expression TLR4;TNF;IL1B;IL6 10844:[DB01183 DB08520] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport OPRM1;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;FKBP1A 10845:[DB01183 DB01291] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways GO:0016579| protein deubiquitination ADRB2;ESR1 GO:1904646| ADRB2;TLR4 GO:0007165| signal transduction OPRK1;ADRB1;CREB1;TLR4;ESR1;ADRB2;OPRM1;OPRD1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;OPRK1;OPRM1;OPRD1;ADRB2 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ADRB2;ESR1 10846:[DB01183 DB02054] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02054|Gabaculine OAT common genes common pathways 10847:[DB01183 DB01646] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01646|N-Acetylmethionine RHO common genes common pathways GO:0007165| signal transduction RHO;TLR4;CREB1;OPRK1;OPRD1;OPRM1;ESR1 GO:0006468| protein phosphorylation RHO;CREB1 GO:0007186| G-protein coupled receptor signaling pathway RHO;OPRK1;OPRM1;OPRD1 10848:[DB01183 DB00183] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00183|Pentagastrin CCKBR;BCHE common genes common pathways GO:0007586| digestion CCKBR;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;CCKBR;ESR1 GO:0007600| sensory perception CCKBR;OPRM1;OPRK1 GO:0042493| response to drug ABCB1;BCHE;UGT1A1;CREB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;CCKBR;ESR1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;CCKBR GO:0007204| elevation of cytosolic calcium ion concentration CCKBR;ESR1;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient BCHE;UGT1A1 10849:[DB01183 DB01088] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0001666| response to hypoxia CREB1;PLAT GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO2B1;ALB GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGIR;OPRD1;OPRM1;PTGDR2 GO:0006811| ion transport SLCO1A2;SLCO3A1;SLCO2B1 GO:0055085| transmembrane transport SLCO2A1;ABCB1;SLCO2B1;SLCO3A1;SLCO1A2 GO:0007165| signal transduction CREB1;PTGIR;TLR4;PDE4B;PDE4C;OPRK1;OPRM1;PTGER1;OPRD1;PDE4A;PDE4D;ESR1;PTGDR2 GO:0043252| sodium-independent organic anion transport SLCO3A1;SLCO1A2;SLCO2A1;SLCO2B1;ALB GO:0007186| G-protein coupled receptor signaling pathway PTGIR;OPRK1;PDE4B;PDE4C;OPRD1;PDE4A;PDE4D;OPRM1;PTGER1;PTGDR2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;PTGDR2;OPRK1 GO:0007568| aging CREB1;PDE4D GO:0006955| immune response TLR4;OPRK1;OPRD1;PTGDR2 GO:0007268| synaptic transmission OPRK1;PTGDR2;OPRD1;OPRM1 GO:0071222| cellular response to lipopolysaccharide PDE4B;OPRK1;TLR4;PDE4D GO:0007218| neuropeptide signaling pathway PTGDR2;OPRD1;OPRM1;OPRK1 GO:0032729| positive regulation of interferon-gamma production PDE4B;TLR4;PDE4D GO:0032496| response to lipopolysaccharide TLR4;PTGIR;UGT1A1;PTGER1;OPRM1 10850:[DB01183 DB02884] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;ZFY;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ZFY;ESR1 10851:[DB01183 DB08575] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways GO:0019233| sensory perception of pain OPRK1;MME;OPRM1;OPRD1 10852:[DB01183 DB02852] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02852|Domoic Acid GRIK2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;GRIK2 GO:0006811| ion transport SLCO1A2;GRIK2 GO:0006810| transport ABCB1;GRIK2 GO:0007268| synaptic transmission GRIK2;OPRM1;OPRD1;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GRIK2 10853:[DB01183 DB06413] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes CYP3A4 common pathways GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1;CYP1A2 GO:0002933| CYP3A5;CYP2C8;CYP3A4 GO:0042220| response to cocaine OPRM1;SLC6A3;OPRK1 GO:0036378| CYP3A4 GO:0055085| transmembrane transport SLC6A3;ABCB1;SLCO1A2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;UGT1A1;CYP2C9;CYP2B6;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0007568| aging SLC6A3;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;SLC6A3 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A5;CYP3A4;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP1A2;CYP3A4 GO:0097267| CYP2C9;CYP2C19;CYP2C8;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2B6;CYP2C19;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;SLC6A3;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A5;CYP2B6;CYP2C9;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0035094| response to nicotine CREB1;SLC6A3 GO:0007595| lactation CREB1;SLC6A3 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;UGT1A1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP3A4;CYP1A2 GO:0045471| response to ethanol SLC6A3;OPRK1;UGT1A1;OPRM1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP3A5;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0007626| locomotory behavior OPRM1;OPRK1;SLC6A3 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9 10854:[DB01183 DB08085] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;CREB1;TLR4;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;THRB GO:0006351| transcription, DNA-dependent THRB;CREB1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;THRB GO:0006367| transcription initiation from RNA polymerase II promoter THRB;ESR1 GO:0060509| Type I pneumocyte differentiation THRB;CREB1 GO:0006355| regulation of transcription, DNA-dependent THRB;CREB1;ESR1 10855:[DB01183 DB07802] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07802|3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CSNK2A1;CREB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;CSNK2A1;ESR1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0048511| rhythmic process CSNK2A1;CREB1 10856:[DB01183 DB08356] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways GO:0006468| protein phosphorylation CREB1;PDK4 GO:0009267| cellular response to starvation PDK4;ALB GO:0042594| response to starvation PDK4;UGT1A1 GO:0071398| cellular response to fatty acid CREB1;PDK4 10857:[DB01183 DB00542] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0006811| ion transport SLC15A2;SLCO1A2;SLC15A1 GO:0055085| transmembrane transport SLC15A2;SLCO1A2;ABCB1;SLC15A1 GO:0001666| response to hypoxia MTHFR;CREB1 GO:0008152| metabolic process MTHFR;CES1;UGT1A1 GO:0007586| digestion UGT1A1;SLC15A1 GO:0042493| response to drug MTHFR;ABCB1;CREB1;UGT1A1 GO:0055114| oxidation-reduction process MTHFR;CYP3A4;CYP2C8 10858:[DB01183 DB12391] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12391|Sagopilone CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 10859:[DB01183 DB13261] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4 10860:[DB01183 DB01790] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PRKAR1A;ESR1 10861:[DB01183 DB08565] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways GO:0007586| digestion CTRB1;UGT1A1 10862:[DB01183 DB03471] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03471|6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid PLA2G2A common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PLA2G2A GO:0050729| positive regulation of inflammatory response TLR4;PLA2G2A GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 10863:[DB01183 DB07749] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways GO:0007586| digestion UGT1A1;CTRB1 10864:[DB01183 DB09120] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes common pathways GO:0010033| response to organic substance CYP1A2;UGT1A1;CREB1 GO:0055085| transmembrane transport SLCO1A2;TRPV1;ABCB1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0006811| ion transport SLCO1A2;TRPV1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;UGT1A1;CYP2C19;CYP2C8 GO:0097267| CYP1A2;CYP2C8;CYP2C19;CYP2C9 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TLR4;OPRM1;ESR1 GO:0070588| calcium ion transmembrane transport OPRM1;TRPV1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2C8 GO:0006810| transport ABCB1;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;OPRM1;ESR1 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2C8;CYP2C19;CYP1A2;CYP2E1;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0071363| cellular response to growth factor stimulus CREB1;TRPV1;OPRD1 GO:0006954| inflammatory response TRPV1;TLR4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2C8;CYP2C19 GO:0042493| response to drug CYP2E1;CYP1A2;CREB1;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP2C8;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;TRPV1;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:1990090| CREB1;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2C9;CES1;CYP3A4;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C19;CYP2C8;CYP2C9 GO:0043065| positive regulation of apoptotic process TRPV1;CREB1 GO:0019233| sensory perception of pain OPRD1;OPRM1;TRPV1;OPRK1 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;CYP2E1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;TRPV1 GO:0042737| drug catabolic process CYP2C9;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 10865:[DB01183 DB06116] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06116|Eldelumab CXCL10 common genes common pathways GO:0051607| defense response to virus CXCL10;OPRK1 GO:0006954| inflammatory response CXCL10;TLR4 GO:0006955| immune response OPRD1;CXCL10;TLR4;OPRK1 GO:0032496| response to lipopolysaccharide OPRM1;CXCL10;UGT1A1;TLR4 GO:0071222| cellular response to lipopolysaccharide CXCL10;TLR4;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CXCL10;CREB1;TLR4;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;CXCL10 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;CXCL10 GO:0007165| signal transduction OPRK1;CXCL10;CREB1;TLR4;OPRM1;OPRD1;ESR1 10866:[DB01183 DB05848] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways GO:0019233| sensory perception of pain IL12B;OPRK1;OPRM1;OPRD1 GO:0050671| positive regulation of lymphocyte proliferation TLR4;IL12B GO:0032729| positive regulation of interferon-gamma production TLR4;IL12B GO:0042088| T-helper 1 type immune response TLR4;IL12B GO:0032733| positive regulation of interleukin-10 production TLR4;IL12B GO:0050829| defense response to Gram-negative bacterium TLR4;IL12B GO:0071222| cellular response to lipopolysaccharide IL12B;OPRK1;TLR4 GO:0045672| positive regulation of osteoclast differentiation IL12B;CREB1 GO:0042346| positive regulation of NF-kappaB import into nucleus IL12B;TLR4 GO:0051607| defense response to virus OPRK1;IL12B GO:0032760| positive regulation of tumor necrosis factor production IL12B;TLR4 GO:0032609| interferon-gamma production IL12B;TLR4 GO:0032700| negative regulation of interleukin-17 production TLR4;IL12B GO:0032735| positive regulation of interleukin-12 production TLR4;IL12B GO:0050729| positive regulation of inflammatory response TLR4;IL12B GO:0010033| response to organic substance IL12B;CREB1;UGT1A1 10867:[DB01183 DB04036] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04036|Coenzyme a Persulfide IVD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;IVD GO:0008152| metabolic process UGT1A1;IVD;CES1 10868:[DB01183 DB07240] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0044267| cellular protein metabolic process ALB;TTR 10869:[DB01183 DB00143] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes CYP3A4 common pathways GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0002933| CYP2C8;CYP3A4 GO:0009636| response to toxin GSTP1;GPX1;CES1 GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0030855| epithelial cell differentiation GSTA1;CES1;GSTA2;GSTK1 GO:0006855| drug transmembrane transport ABCC1;ABCC3;ABCB1;ABCC2 GO:0055085| transmembrane transport SLCO1A2;ABCC4;ABCC1;ABCC3;ABCB1;ABCC5;ABCC2 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;ABCC3 GO:0010033| response to organic substance CREB1;AKR1B1;UGT1A1;ABCC4;GLRX2 GO:0043627| response to estrogen stimulus ESR1;GSTM3;OPRK1;ABCC2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0050729| positive regulation of inflammatory response MGST2;TLR4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0042908| xenobiotic transport ABCB1;ABCC3;ABCC1 GO:0007568| aging CREB1;GSS;GLRX2 GO:0006810| transport ABCC5;ABCC2;ABCB1;ABCC1;ABCC3 GO:0030154| cell differentiation CREB1;GLRX2;TXNDC12 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0098869| GPX2;GSTK1;MGST3;GPX1;GSTO2;GPX3;GPX5;GSTO1;GPX8;MGST2;GPX4;GSTT1;LTC4S;GPX6;MGST1;GSR;ALB;GSTA1;GSTZ1;GSTP1;GPX7;GSTM2 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;HPGDS;CREB1;TLR4;OPRK1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0015711| organic anion transport SLCO1A2;ABCC5 GO:0042493| response to drug ABCC4;MGST1;ABCC2;ABCB1;CREB1;ABCC1;UGT1A1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent GLRX2;ESR1;CREB1 GO:0055114| oxidation-reduction process MGST1;CYP2C8;GSR;GPX6;GPX7;AKR1B1;TXNDC12;GSTK1;GPX2;ABCC4;GSTO2;GLRX2;GPX1;GPX8;GPX3;GPX5;CYP3A4;GSTO1;GPX4;GLRX GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1;GSTP1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;GLO1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ABCC2;MGST1;OPRM1;MGST2 GO:0045471| response to ethanol OPRK1;GSTP1;UGT1A1;OPRM1 GO:0042737| drug catabolic process CYP3A4 GO:0008152| metabolic process GSTA5;UGT1A1;GSTM1;GSTM2;GSTM3;GSTP1;GSTA4;GSTZ1;GSTA1;GSTA3;GSTA2;CES1;GSTM5;GSTO1;GSTO2;GSTM4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;GGT1;MGST2;MGST3;GSTO2;CYP2C8;MGST1;GSTP1;GSTA4 GO:0043066| negative regulation of apoptotic process GLO1;GPX1;AKR1B1;MMP9;GSTP1;ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0043065| positive regulation of apoptotic process MMP9;CREB1 GO:0050727| regulation of inflammatory response GGT1;ESR1;TLR4 GO:0007626| locomotory behavior OPRK1;HPGDS;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;GSTP1;ABCC2;OPRK1 GO:0006629| lipid metabolic process MGST3;HPGDS;GPX1;GPX5;CYP3A4;MGST2 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0006706| steroid catabolic process CYP3A4 10870:[DB01183 DB04834] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04834|Rapacuronium CHRM2 common genes common pathways GO:0007165| signal transduction ESR1;CHRM2;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CHRM2;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 10871:[DB01183 DB03176] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03176|KB-141 THRB;THRA common genes common pathways GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1;THRA GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;THRA;THRB GO:0006351| transcription, DNA-dependent THRA;CREB1;THRB;ESR1 GO:0043401| steroid hormone mediated signaling pathway THRB;THRA;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;THRB;TLR4;CREB1;THRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;THRA;CREB1;THRB GO:0060509| Type I pneumocyte differentiation THRB;THRA;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter THRB;THRA;ESR1 10872:[DB01183 DB01785] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;IDI1;FDPS GO:0016032| viral reproduction CREB1;FDPS GO:0006695| cholesterol biosynthetic process CES1;FDPS;IDI1 GO:0006629| lipid metabolic process IDI1;FDPS;CYP3A4 10873:[DB01183 DB14039] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14039|Erenumab CALCRL common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CALCRL GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CALCRL;OPRK1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CALCRL;CREB1;TLR4 10874:[DB01183 DB03683] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process MMP9;ALB GO:0043065| positive regulation of apoptotic process CREB1;MMP9 10875:[DB01183 DB03393] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways GO:0016032| viral reproduction CREB1;PPIA 10876:[DB01183 DB01025] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways GO:0042742| defense response to bacterium TLR4;S100A12 GO:0006955| immune response OPRD1;IL3;TLR4;OPRK1 GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A12;TLR4 GO:0006954| inflammatory response S100A12;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;S100A13;S100A12 GO:0045087| innate immune response TLR4;S100A12 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;S100A12 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;ESR1;CREB1;TLR4 GO:0000187| activation of MAPK activity FGF1;TLR4 GO:0030154| cell differentiation FGF1;CREB1 GO:0050729| positive regulation of inflammatory response S100A12;TLR4 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;FGF1;CREB1;TLR4;OPRK1 GO:0002376| immune system process S100A12;TLR4 10877:[DB01183 DB03744] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways GO:0070266| necroptosis PYGL;TLR4 GO:0008152| metabolic process CES1;UGT1A1;PYGL 10878:[DB01183 DB01613] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;NPR1;OPRD1;OPRM1 GO:0006468| protein phosphorylation NPR1;NPR2;CREB1 10879:[DB01183 DB02016] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02016|R048-8071 LSS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;LSS GO:0006695| cholesterol biosynthetic process LSS;CES1 10880:[DB01183 DB02211] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02211|N-Methyl-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0009636| response to toxin MAOB;CES1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;MAOB GO:0045471| response to ethanol OPRM1;OPRK1;MAOB;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;MAOB;CREB1 GO:0055114| oxidation-reduction process CYP3A4;MAOB;CYP2C8 10881:[DB01183 DB01878] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01878|Benzophenone ESR1;ESR2 common genes ESR1 common pathways GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006351| transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0060065| uterus development ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;ESR2 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus ESR2;UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;ESR1;OPRM1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;ESR2;OPRK1;CREB1;TLR4 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 10882:[DB01183 DB03070] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways GO:0007623| circadian rhythm IMPDH2;CREB1 GO:0055114| oxidation-reduction process IMPDH2;CYP3A4;CYP2C8 10883:[DB01183 DB06089] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways GO:0007268| synaptic transmission OPRD1;OPRM1;KCNQ3;KCNQ2;OPRK1 GO:0055085| transmembrane transport ABCB1;KCNQ1;KCNQ4;KCNQ2;KCNQ5;KCNQ3;SLCO1A2 GO:0006811| ion transport KCNQ5;KCNQ2;KCNQ3;SLCO1A2;KCNQ1;KCNQ4 GO:1901381| KCNQ1;OPRK1 10884:[DB01183 DB00012] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00012|Darbepoetin alfa EPOR common genes common pathways GO:0007165| signal transduction EPOR;ESR1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 10885:[DB01183 DB09119] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes UGT1A1;CYP3A4 common pathways GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0042594| response to starvation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0007586| digestion UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0008152| metabolic process CES1;UGT1A1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C19 GO:0097190| apoptotic signaling pathway P2RX4;TLR4 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1 GO:0042737| drug catabolic process CYP3A4 GO:1904224| UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential P2RX4;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRD1;OPRM1;P2RX4 GO:0001889| liver development UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0006811| ion transport P2RX4;SLCO1A2 GO:0002933| CYP2C8;CYP3A4 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0097267| CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0007165| signal transduction OPRD1;OPRM1;P2RX4;ESR1;OPRK1;TLR4;CREB1 GO:0031100| organ regeneration UGT1A1 GO:0070588| calcium ion transmembrane transport OPRM1;P2RX4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;P2RX4;ESR1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4 10886:[DB01183 DB03929] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0006810| transport ABCB1;SLC6A14 GO:0007613| memory GRIN1;CREB1 GO:1904646| TLR4;GRIN1 GO:1903428| TLR4;GRIN1 GO:0008344| adult locomotory behavior OPRD1;GRIN1 GO:0055085| transmembrane transport ABCB1;SLC6A14;SLCO1A2;SLC16A10 GO:0009636| response to toxin CES1;SLC6A14 GO:0006811| ion transport GRIN1;SLCO1A2;GLRA1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;TLR4;CREB1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRA1;OPRD1;OPRM1 GO:0019233| sensory perception of pain GRIN1;OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol UGT1A1;OPRK1;GRIN1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;OPRM1;GRIN1 GO:0071294| cellular response to zinc ion CREB1;GLRA1 GO:0043278| response to morphine GRIN1;OPRM1;OPRK1 GO:0008542| visual learning CREB1;GRIN1 GO:0043086| negative regulation of catalytic activity UGT1A1;SERPINB3 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA1;OPRK1 10887:[DB01183 DB08100] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 10888:[DB01183 DB04523] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04523|Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 10889:[DB01183 DB04673] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04673|4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE F10 common genes common pathways 10890:[DB01183 DB04924] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04924|Itopride DRD2;ACHE common genes common pathways GO:0035094| response to nicotine DRD2;CREB1 GO:0043278| response to morphine OPRK1;DRD2;OPRM1 GO:0008542| visual learning DRD2;CREB1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;DRD2 GO:0048148| behavioral response to cocaine OPRK1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;DRD2;TLR4;CREB1 GO:0007626| locomotory behavior OPRM1;OPRK1;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol OPRM1;OPRK1;DRD2;UGT1A1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0008285| negative regulation of cell proliferation OPRM1;DRD2 GO:0001666| response to hypoxia CREB1;DRD2 GO:0042220| response to cocaine OPRM1;DRD2;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;DRD2 GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 GO:0007165| signal transduction TLR4;CREB1;DRD2;OPRK1;OPRD1;OPRM1;ESR1 GO:1900273| CREB1;DRD2 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;DRD2 10891:[DB01183 DB12455] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes ALB;ABCB1 common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0051659| maintenance of mitochondrion location ALB GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0045332| phospholipid translocation ABCB1 GO:0009267| cellular response to starvation ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006810| transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:1901529| ABCB1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 10892:[DB01183 DB04322] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04322|LY249543 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process MTHFD1;CYP2C8;CYP3A4 GO:0008152| metabolic process CES1;UGT1A1;MTHFD1 10893:[DB01183 DB04575] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04575|Quinestrol ESR1 common genes ESR1 common pathways GO:0032355| response to estradiol stimulus ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1 GO:0002064| epithelial cell development ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 10894:[DB01183 DB06350] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06350|Elinogrel P2RY12 common genes common pathways GO:0043491| protein kinase B signaling cascade CREB1;P2RY12 GO:0051924| regulation of calcium ion transport OPRD1;P2RY12 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;P2RY12 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway P2RY12;OPRD1;OPRM1;OPRK1 GO:0070588| calcium ion transmembrane transport P2RY12;OPRM1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1;P2RY12 10895:[DB01183 DB08039] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways GO:0055085| transmembrane transport ABCB1;CALM1;SLCO1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;OPRM1;CALM1 GO:0030154| cell differentiation CREB1;CAMK2D GO:0006468| protein phosphorylation CREB1;CAMK2D GO:0002576| platelet degranulation ALB;CALM1 GO:0006357| regulation of transcription from RNA polymerase II promoter CAMK2D;ESR1 10896:[DB01183 DB13985] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;SSTR3;SSTR2;SSTR1;OPRK1 GO:0042594| response to starvation SSTR1;UGT1A1;SSTR2;SSTR3 GO:0007586| digestion SSTR2;UGT1A1;SSTR1 GO:0071385| cellular response to glucocorticoid stimulus SSTR5;SSTR3;SSTR4;UGT1A1;SSTR2 GO:0007268| synaptic transmission SSTR5;OPRM1;OPRD1;SSTR3;SSTR4;OPRK1 GO:0007165| signal transduction SSTR1;CREB1;TLR4;SSTR2;OPRK1;SSTR4;ESR1;SSTR3;OPRM1;OPRD1;SSTR5 GO:0007186| G-protein coupled receptor signaling pathway SSTR3;OPRD1;OPRM1;SSTR5;SSTR1;SSTR2;OPRK1;SSTR4 GO:0071392| cellular response to estradiol stimulus UGT1A1;SSTR2;SSTR1;ESR1;SSTR3 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;SSTR2;OPRK1 GO:1990830| CREB1;SSTR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger SSTR2;SSTR1;SSTR4;OPRD1;OPRM1;SSTR3;SSTR5 GO:0007584| response to nutrient SSTR1;UGT1A1;SSTR2 GO:0008285| negative regulation of cell proliferation SSTR1;SSTR2;SSTR4;SSTR3;OPRM1;SSTR5 10897:[DB01183 DB04615] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways 10898:[DB01183 DB01567] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0006811| ion transport GABRA5;GABRA3;GABRG1;GABRR2;GABRP;GABRD;GABRB2;GABRA2;GABRG2;GABRB1;SLCO1A2;GABRE;GABRA1;GABRR1;GABRR3;GABRG3;GABRB3 GO:0009636| response to toxin GABRB1;CES1 GO:0006810| transport ABCB1;GABRB2;GABRD;GABRR2;GABRA3;GABRA5;GABRB3;GABRR1;GABRA1;GABRB1;GABRG2 GO:0007165| signal transduction OPRK1;GABRD;CREB1;TLR4;GABRP;GABRR2;GABRA5;GABRB3;ESR1;GABRE;OPRM1;OPRD1;GABRB1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;GABRG3 GO:0007268| synaptic transmission GABRB2;GABRD;GABRA5;GABRR2;GABRG1;OPRK1;GABRR1;OPRD1;GABRG2;OPRM1;GABRR3 GO:1901215| GABRB3;GABRB2;CREB1 10899:[DB01183 DB08323] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08323|3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE IGHG2 common genes common pathways GO:0002376| immune system process IGHG2;TLR4 GO:0045087| innate immune response IGHG2;TLR4 GO:0042742| defense response to bacterium IGHG2;TLR4 10900:[DB01183 DB04376] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04376|13-Acetylphorbol PRKCD common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;PRKCD;ESR1;OPRM1;OPRD1 GO:0006468| protein phosphorylation PRKCD;CREB1 GO:0050821| protein stabilization CREB1;PRKCD GO:0042742| defense response to bacterium TLR4;PRKCD 10901:[DB01183 DB00771] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00771|Clidinium CHRM1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;CHRM1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1;CHRM1 10902:[DB01183 DB05468] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05468|R411 ITGA4 common genes common pathways 10903:[DB01183 DB07021] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 10904:[DB01183 DB06367] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06367|Relacatib CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway CTSK;TLR4 10905:[DB01183 DB07202] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;CSF1R;ESR1;OPRM1;OPRD1 GO:0002376| immune system process TLR4;CSF1R GO:0006468| protein phosphorylation CREB1;CSF1R GO:0008285| negative regulation of cell proliferation OPRM1;CSF1R GO:0007411| axon guidance CREB1;CSF1R GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CSF1R;TLR4 GO:0045087| innate immune response CSF1R;TLR4 GO:0043066| negative regulation of apoptotic process CSF1R;ALB GO:0006954| inflammatory response TLR4;CSF1R 10906:[DB01183 DB08791] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;MET GO:0007165| signal transduction MET;OPRM1;OPRD1;ESR1;CREB1;TLR4;OPRK1 GO:0006468| protein phosphorylation MET;CREB1 10907:[DB01183 DB08398] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08398|2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine ESR1;NCOA2 common genes ESR1 common pathways GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0060065| uterus development ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;TLR4;CREB1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;CREB1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1903799| ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0048511| rhythmic process NCOA2;CREB1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0008584| male gonad development ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;ALB GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 10908:[DB01183 DB00107] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0042493| response to drug ABCB1;CREB1;UGT1A1;OXTR GO:0032094| response to food OPRM1;OXT GO:0042711| maternal behavior OXT;OXTR;OPRK1 GO:0007595| lactation CREB1;OXTR GO:0032355| response to estradiol stimulus OXTR;ESR1;OXT GO:0051384| response to glucocorticoid stimulus OXT;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OXT;OPRD1;OXTR;OPRK1 GO:0007613| memory OXT;OXTR;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;OXT;ESR1;OXTR GO:0044849| OPRK1;OXTR;OPRM1 GO:0032870| cellular response to hormone stimulus UGT1A1;OXTR GO:0048545| response to steroid hormone stimulus UGT1A1;OXT;OXTR GO:0007165| signal transduction OPRK1;TLR4;CREB1;OXTR;ESR1;OPRD1;OXT;OPRM1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OXT;OPRD1 GO:0042755| eating behavior OPRK1;OXT;OPRM1;OPRD1;OXTR GO:0014070| response to organic cyclic compound UGT1A1;OXT;OXTR GO:0042220| response to cocaine OXTR;OXT;OPRM1;OPRK1 GO:0014823| response to activity OXT;CREB1 10909:[DB01183 DB00177] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00177|Valsartan AGTR1;CYP2C9;ALB;SLCO1B3;SLCO1B1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1;SLCO1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006811| ion transport SLCO1B1;SLCO1B3;SLCO1A2 GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0055085| transmembrane transport SLCO1B3;SLCO1B1;SLCO1A2;ABCB1 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;AGTR1 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0015711| organic anion transport SLCO1B1;SLCO1B3;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B1;SLCO1B3;ALB GO:0009267| cellular response to starvation ALB GO:0050729| positive regulation of inflammatory response TLR4;AGTR1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;CYP2C9 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;AGTR1;OPRK1 GO:0043069| negative regulation of programmed cell death ALB GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;AGTR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0050727| regulation of inflammatory response TLR4;ESR1;AGTR1 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;AGTR1;OPRK1 GO:0042737| drug catabolic process CYP2C9;CYP3A4 10910:[DB01183 DB00659] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0043065| positive regulation of apoptotic process CREB1;GRIN2A;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;TLR4;CREB1 GO:0007626| locomotory behavior OPRK1;GRM5;OPRM1 GO:0019233| sensory perception of pain OPRM1;GRIN1;OPRD1;GRIN2A;OPRK1 GO:0045471| response to ethanol GRIN2A;GRIN2B;OPRM1;GRIN1;OPRK1;GRIN3A;UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2A;OPRM1;GRIN1;GRIN2D;GRIN2B;GRIN3B;GRIN2C;GRIN3A GO:0043278| response to morphine GRIN1;OPRM1;OPRK1 GO:0008542| visual learning CREB1;GRIN2A;GRIN1 GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:1901215| GABRB3;GABRB2;CREB1 GO:0007268| synaptic transmission GABRD;GABRB2;GABRG1;GABRA5;OPRK1;GRIN2B;OPRM1;GRM5;OPRD1;GABRG2;GRIN2A GO:0042493| response to drug GRIN2A;GABRG3;CREB1;UGT1A1;ABCB1 GO:0007165| signal transduction CREB1;GABRD;TLR4;GABRP;GABRA5;OPRK1;ESR1;GABRA6;GABRE;OPRM1;GABRQ;OPRD1;GRM5;GABRB1;GABRB3 GO:1900273| CREB1;GRIN2A GO:0070588| calcium ion transmembrane transport GRIN3B;GRIN3A;OPRM1 GO:0006810| transport ABCB1;GABRD;GABRB2;GRIN2C;GABRA5;GABRA3;GABRB3;GRIN2A;GABRA6;GABRA4;GRIN2B;GABRA1;GABRB1;GABRG2 GO:0007613| memory CREB1;GRIN2A;GRIN1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GRM5;OPRD1;OPRM1 GO:1904646| TLR4;GRIN2A;GRM5;GRIN1 GO:1903428| TLR4;GRIN1 GO:0008344| adult locomotory behavior OPRD1;GRIN1;GRIN2D GO:0055085| transmembrane transport ABCB1;SLC36A1;SLCO1A2 GO:0009636| response to toxin CES1;GABRB1 GO:0006811| ion transport GABRE;GRIN2D;GRIN1;GABRG2;GABRB1;SLCO1A2;GABRQ;GABRA6;GABRA4;GRIN2B;GABRA1;SLC36A1;GABRB3;GABRG3;GRIN2A;GABRG1;GRIN2C;GABRA5;GABRA3;GRIN3A;GABRD;GABRB2;GABRP;GRIN3B;GABRA2 GO:0051930| regulation of sensory perception of pain OPRM1;GRIN2D;OPRD1;GRIN2A;OPRK1 10911:[DB01183 DB05540] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways GO:0002376| immune system process ADSS;ADSSL1;TLR4 GO:0009636| response to toxin CES1;SLC7A11 GO:0042594| response to starvation UGT1A1;ADSSL1 GO:0035094| response to nicotine SLC7A11;CREB1 10912:[DB01183 DB03331] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03331|N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;GAPDHS;CYP3A4 10913:[DB01183 DB09043] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09043|Albiglutide GLP1R common genes common pathways GO:0007165| signal transduction OPRK1;GLP1R;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway GLP1R;OPRK1;OPRD1;OPRM1 10914:[DB01183 DB00239] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;NR1I2;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I2;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0042737| drug catabolic process CYP3A4 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR1I2 GO:0006351| transcription, DNA-dependent NR1I2;CREB1;ESR1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;NR1I2;TLR4;ESR1 GO:0006805| xenobiotic metabolic process NR1I2;CYP2C19;CYP2C8;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0010628| positive regulation of gene expression TLR4;NR1I2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0008202| steroid metabolic process CYP3A4;NR1I2;UGT1A1;CYP2C19;CYP2C8 GO:0007165| signal transduction OPRK1;CREB1;NR1I2;TLR4;ESR1;OPRM1;OPRD1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C19;UGT1A1 GO:0097267| CYP2C8;CYP2C19 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 10915:[DB01183 DB00666] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;GNRHR;GNRHR2 GO:0007165| signal transduction TLR4;CREB1;OPRK1;GNRHR;GNRHR2;ESR1;OPRD1;OPRM1 10916:[DB01183 DB07697] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07697|1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine PKM common genes common pathways GO:0031100| organ regeneration UGT1A1;PKM GO:0007584| response to nutrient UGT1A1;PKM GO:0010033| response to organic substance PKM;UGT1A1;CREB1 GO:0001666| response to hypoxia CREB1;PKM GO:0032868| response to insulin stimulus PKM;OPRK1 GO:0008152| metabolic process CES1;PKM;UGT1A1 GO:0001889| liver development PKM;UGT1A1 10917:[DB01183 DB03959] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03959|N,O6-Disulfo-Glucosamine FGF2;FGF1;HS3ST3A1;HGF;ANXA5 common genes common pathways GO:0035729| cellular response to hepatocyte growth factor stimulus HGF;CREB1 GO:0032715| negative regulation of interleukin-6 production TLR4;HGF GO:0010863| positive regulation of phospholipase C activity ESR1;FGF2 GO:0031100| organ regeneration HGF;UGT1A1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;OPRM1;FGF2;ANXA5;FGF1;ESR1 GO:0072089| stem cell proliferation ABCB1;FGF2 GO:0030154| cell differentiation FGF1;FGF2;CREB1 GO:0010033| response to organic substance ANXA5;UGT1A1;CREB1 GO:0000187| activation of MAPK activity HGF;TLR4;FGF1;FGF2 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF2;OPRM1;TLR4 GO:0043066| negative regulation of apoptotic process ANXA5;HGF;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;ESR1;FGF1;HGF;CREB1;TLR4 GO:0002576| platelet degranulation HGF;ALB;ANXA5 GO:0032733| positive regulation of interleukin-10 production HGF;TLR4 GO:0042060| wound healing FGF2;OPRM1 GO:0001889| liver development UGT1A1;HGF GO:0045893| positive regulation of transcription, DNA-dependent ESR1;FGF2;CREB1 GO:0043086| negative regulation of catalytic activity UGT1A1;ANXA5 10918:[DB01183 DB06982] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06982|(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid SKP1 common genes common pathways GO:0043687| post-translational protein modification ALB;SKP1 GO:0000086| G2/M transition of mitotic cell cycle SKP1;ABCB1 10919:[DB01183 DB04224] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0042060| wound healing PPARA;PPARD;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA;ESR1;PPARD GO:0006351| transcription, DNA-dependent PPARG;CREB1;RXRA;PPARD;PPARA;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARA;ESR1;RXRA;PPARG GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0043066| negative regulation of apoptotic process ALB;FABP1;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;RXRA;TLR4;ESR1;PPARA GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PPARD GO:0002576| platelet degranulation ALB GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0050727| regulation of inflammatory response TLR4;ESR1;FABP4 GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARD;CYP3A4;PPARA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;PPARA;ESR1;PPARD GO:0045087| innate immune response PPARG;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;CREB1;ESR1;PPARA;PPARD GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;RXRA;ESR1;PPARA;PPARD GO:0042493| response to drug FABP3;ABCB1;UGT1A1;CREB1;PPARG GO:0043687| post-translational protein modification ALB GO:1901215| CREB1;PPARA GO:0016032| viral reproduction CREB1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1;RXRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;PPARD;PPARA;ESR1 GO:0042752| regulation of circadian rhythm PPARA;PPARG;CREB1 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0009267| cellular response to starvation ALB GO:0050729| positive regulation of inflammatory response TLR4;FABP4 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway PPARG;OPRK1;OPRM1;OPRD1 GO:0043069| negative regulation of programmed cell death ALB GO:0071456| cellular response to hypoxia OPRD1;PPARD;FABP1 GO:0030154| cell differentiation PPARD;CREB1 GO:0098869| ALB;FABP1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0006898| receptor-mediated endocytosis ALB GO:0007165| signal transduction PPARG;CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0001895| retina homeostasis ALB GO:0032868| response to insulin stimulus PPARA;OPRK1;FABP3 GO:0010628| positive regulation of gene expression PPARD;TLR4 GO:0001666| response to hypoxia CREB1;PPARA GO:0042359| vitamin D metabolic process GC;CYP3A4 GO:0015721| bile acid and bile salt transport SLCO1A2;RXRA;ALB GO:0045600| positive regulation of fat cell differentiation PPARD;CREB1;PPARG GO:0014823| response to activity CREB1;PPARD GO:0008285| negative regulation of cell proliferation PPARG;FABP3;FABP7;OPRM1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1;PPARD GO:0048511| rhythmic process CREB1;PPARG;PPARA GO:0007584| response to nutrient PPARG;UGT1A1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 10920:[DB01183 DB06719] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LHCGR;ESR1;OPRM1;OPRD1;OPRK1 GO:0060065| uterus development ESR1;CYP19A1 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP19A1;CYP2C8;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GNRHR;LHCGR;OPRD1;OPRM1 GO:0007165| signal transduction CREB1;TLR4;GNRHR;OPRK1;LHCGR;ESR1;OPRM1;OPRD1 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger LHCGR;OPRM1;OPRD1 GO:0008584| male gonad development ESR1;LHCGR 10921:[DB01183 DB14487] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes ESR1 common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;APP GO:0007165| signal transduction BDKRB1;PDIA3;CREB1;TLR4;FGA;IGFALS;OPRK1;OPRM1;OPRD1;ESR1;C3;JUP GO:0048545| response to steroid hormone stimulus UGT1A1;MDM2 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0006898| receptor-mediated endocytosis APOL1;IGLV3-21;VTN;IGHA1;CFI;IGKV1-17;APOBR;JCHAIN;ALB;APOA1;APOE;HBB;HBA1;HPR GO:0032689| negative regulation of interferon-gamma production PGLYRP2;TLR4 GO:0031100| organ regeneration APOA2;UGT1A1;APOA1 GO:0002376| immune system process C4BPB;C8A;S100A9;IGLV3-21;S100A8;C1QC;C3;CFI;IGHA1;C1S;C5;C4B;C8G;C4BPA;PGLYRP2;C1QB;C8B;C1R;CLU;TLR4;IGHM;FGA;FCN3;CFH;CFB;IGKV1-17 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:1900273| APP;CREB1;INS GO:0045429| positive regulation of nitric oxide biosynthetic process AGT;INS;OPRM1;ESR1;CLU;APP;TLR4;HBB GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0098869| ALB;HBB;HBA1;APOE;S100A9 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;AGT;APP;BDKRB1;KNG1 GO:0071456| cellular response to hypoxia OPRD1;P4HB;MT3;TP53;MDM2 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0007613| memory CREB1;APP GO:0006468| protein phosphorylation APP;CREB1 GO:0030154| cell differentiation CREB1;TP53;NME1;KRT6A GO:0006338| chromatin remodeling ESR1;HDAC4;HDAC1 GO:0006810| transport ABCB1;TTR GO:0007568| aging CREB1;KRT16;KRT14;TP53;AGT;SOD1;GSN GO:0002224| toll-like receptor signaling pathway S100A8;S100A9;TLR4;FGA GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRK1;OPRD1;OPRM1 GO:0032732| positive regulation of interleukin-1 production HDAC1;TLR4 GO:0071363| cellular response to growth factor stimulus MDM2;CREB1;OPRD1 GO:0050821| protein stabilization CLU;CREB1;CPN2;APOA1;MT3 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;C3;APLP2;C5;AGT;INS;APP;BDKRB1;APOE;F2;KNG1;APOA1;OPRK1 GO:0014002| astrocyte development TLR4;S100A9;S100A8;MT3 GO:0032355| response to estradiol stimulus AGT;ESR1 GO:0051384| response to glucocorticoid stimulus APOA2;UGT1A1;CPN1 GO:0008202| steroid metabolic process APOL1;CYP3A4;CYP2C8;APOA1;APOBR;UGT1A1;APOE GO:0050729| positive regulation of inflammatory response TLR4;AGT;S100A8;S100A9 GO:0048511| rhythmic process TP53;HDAC1;CREB1 GO:0007584| response to nutrient UGT1A1;APOA1 GO:0043627| response to estrogen stimulus ESR1;APOA1;OPRK1;APOA2 GO:0008285| negative regulation of cell proliferation HDAC1;HDAC4;TP53;APP;TP73;OPRM1;NME1 GO:1903223| TLR4;APP GO:0010033| response to organic substance CREB1;UGT1A1;SOD1 GO:0016579| protein deubiquitination MDM2;TP53;ESR1;BRCC3 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity HDAC4;ESR1 GO:0032460| negative regulation of protein oligomerization OPRD1;INS GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:1903428| TLR4;HDAC4 GO:0048146| positive regulation of fibroblast proliferation ESR1;AGT;FN1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0001666| response to hypoxia MT3;CREB1 GO:1904646| TLR4;APP;PARP1 GO:0010628| positive regulation of gene expression GSN;MT3;INS;MDM2;TP53;APP;CLU;TLR4;FN1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0055085| transmembrane transport SLCO1A2;APOA1;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;MT3;S100A7;TLR4;APP;FGA GO:0006366| transcription from RNA polymerase II promoter ESR1;PARP1;CREB1;TP53;TP73 GO:0044267| cellular protein metabolic process INS;TTR;SERPINA1;CP;SERPIND1;APLP2;C3;ITIH2;APOL1;GSN;P4HB;APCS;TF;IGFALS;AHSG;ALB;APOA1;KNG1;F2;FGA;SEMG1;FN1;APOE;APOA4;APOA2;APP GO:0007179| transforming growth factor beta receptor signaling pathway APOA1;CREB1;PARP1 GO:0008344| adult locomotory behavior OPRD1;APP GO:0001895| retina homeostasis IGHA1;SOD1;TF;KRT1;JCHAIN;ALB;PRDX1 GO:0030855| epithelial cell differentiation CES1;KRT14 GO:0042220| response to cocaine OPRK1;MDM2;OPRM1 GO:0000187| activation of MAPK activity APP;TLR4;TP73;C5;SOD1 GO:0030879| mammary gland development NME1;CREB1 GO:0007409| axonogenesis APP;CREB1 GO:0006811| ion transport GLRA1;CP;TF;SLCO1A2 GO:0014070| response to organic cyclic compound TP53;UGT1A1;MGMT GO:0009636| response to toxin MDM2;PON1;CES1;MGMT GO:0034375| high-density lipoprotein particle remodeling APOA1;ALB;APOA2;APOA4;APOE GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;INS GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0042981| regulation of apoptotic process TP73;CREB1;TP53;NME1;AGT;ESR1 GO:0045087| innate immune response PGLYRP2;C4BPA;C8G;C4B;C3;CFI;C1QC;C1S;C5;IGHA1;F12;APCS;C4BPB;C8A;S100A9;S100A8;APOL1;JCHAIN;CFB;FGA;CFH;FCN3;S100A7;TLR4;IGHM;KRT16;APP;C1R;C1QB;C8B;CLU GO:0000122| negative regulation of transcription from RNA polymerase II promoter TP73;ENO1;MDM2;APP;TP53;HDAC4;HDAC1;HDAC8;PARP1;ESR1 GO:1990090| CREB1;APP GO:0071260| cellular response to mechanical stimulus AGT;HDAC4;TLR4 GO:0006629| lipid metabolic process APOE;CLU;APOBR;APOA1;APOL1;CYP3A4;PON1;C3 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0050829| defense response to Gram-negative bacterium DCD;APP;IGHM;TLR4;S100A7 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0007626| locomotory behavior APP;OPRK1;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;ESR1;TP73;TP53;APP;CREB1;HDAC4;TLR4;HDAC1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRA1;OPRM1;CPE;OPRD1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response AHSG;TLR4;PGLYRP2;ESR1;S100A9;S100A8 GO:0002576| platelet degranulation APP;ALDOA;SERPINA4;CLU;ORM2;FN1;KNG1;FGA;SERPINA3;A1BG;AHSG;APOA1;ALB;ITIH3;TF;APLP2;SOD1;ITIH4;SERPINA1;A2M GO:0043065| positive regulation of apoptotic process SOD1;APP;TP53;CLU;MMP9;CREB1;KNG1;TP73 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0060065| uterus development ESR1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PARP1 GO:0043066| negative regulation of apoptotic process ALB;TP53;MDM2;HDAC1;MMP9;MT3;SOD1;MGMT GO:0071398| cellular response to fatty acid NME1;CREB1 GO:0008152| metabolic process CES1;CPE;TPI1;IDE;ASPA;UGT1A1 GO:0042346| positive regulation of NF-kappaB import into nucleus APP;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;OPRM1 GO:0097190| apoptotic signaling pathway PDCD6;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1;AGT GO:0045471| response to ethanol TUFM;OPRK1;TP53;UGT1A1;OPRM1;GSN;S100A8;SOD1;MGMT GO:0000060| protein import into nucleus, translocation OPRD1;MT3 GO:0019233| sensory perception of pain OPRK1;BDKRB1;OPRM1;OPRD1 GO:0006351| transcription, DNA-dependent ENO1;TP73;HDAC1;EEF1A1;HDAC4;CREB1;TP53;HDAC8;ESR1;PARP1 GO:0046330| positive regulation of JNK cascade TLR4;APP GO:0006695| cholesterol biosynthetic process CES1;APOA1;APOA4 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;INS;APOE GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;BDKRB1;HDAC1;S100A7;TLR4;OPRM1;S100A8 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;APOE GO:0042060| wound healing KRT6A;S100A8;OPRM1;GSN;INS;TP53;FN1;DSP GO:0071294| cellular response to zinc ion MT1A;MT2A;GLRA1;CREB1;PARP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0046889| positive regulation of lipid biosynthetic process CREB1;APOE;INS GO:0007595| lactation NME1;CREB1 GO:0032760| positive regulation of tumor necrosis factor production HDAC1;TLR4;CLU GO:0051924| regulation of calcium ion transport OPRD1;AGT GO:0006953| acute-phase response FN1;ORM2;UGT1A1;AHSG;SERPINA3;F2;ITIH4;APCS;INS;SERPINA1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0048863| stem cell differentiation A2M;ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0043278| response to morphine OPRM1;OPRK1;MDM2 GO:0008542| visual learning CREB1;APP GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0050718| positive regulation of interleukin-1 beta secretion ORM2;TLR4 GO:0006954| inflammatory response TLR4;KRT16;HDAC4;BDKRB1;KNG1;SERPINA3;C3;KLKB1;C5;S100A9;S100A8;C4B GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1;MDM2 GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CLU;APP;TLR4;S100A8;S100A9;AGT;INS GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;APP;ESR1;JUP GO:0016032| viral reproduction CFH;TP73;TP53;MDM2;APOA2;HDAC1;IDE;CREB1;SIVA1 GO:0006955| immune response IGKV1-17;JCHAIN;OPRK1;TLR4;C8B;C1R;IL3;IGHA1;C1QC;C3;IGLV3-21;VTN;C8A;OPRD1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CP;CCS;ADH1C;P4HB;CYP3A4;SOD1;PRDX1;CYP2C8;PDIA3;GAPDHS GO:0043687| post-translational protein modification SERPINA1;CP;SERPIND1;C3;APLP2;P4HB;ITIH2;APOL1;TF;ALB;APOA1;AHSG;FGA;KNG1;FN1;APOE;APP;APOA2 GO:0043491| protein kinase B signaling cascade MDM2;CREB1;MT3 GO:0042742| defense response to bacterium S100A9;S100A8;DCD;TLR4 GO:1901215| MT3;APOE;APP;CREB1 GO:0006355| regulation of transcription, DNA-dependent TP53;HDAC4;CREB1;HDAC1;EEF1A1;ENO1;TP73;PARP1;ESR1;HDAC8;INS GO:0051607| defense response to virus OPRK1;FCN3 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression MDM2;APP;CREB1;HDAC1;OPRD1;ESR1;AGT;HDAC8;NME1 GO:0042493| response to drug MGMT;SOD1;NME1;UGT1A1;TP53;MDM2;APOA2;HDAC4;CREB1;HDAC1;ABCB1;TP73;APOA1 GO:0007268| synaptic transmission OPRM1;OPRD1;OPRK1;GLRA1;APP GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AGT;MT3;TP53;HDAC4;CREB1;HDAC1;TP73 GO:0045416| positive regulation of interleukin-8 biosynthetic process APOA2;TLR4 10922:[DB01183 DB05490] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05490|T131 PPARG common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;PPARG GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;PPARG;CREB1;OPRK1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process CREB1;PPARG GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0010033| response to organic substance PPARG;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response TLR4;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation UGT1A1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;PPARG;CREB1;ESR1 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0042493| response to drug ABCB1;CREB1;PPARG;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0042752| regulation of circadian rhythm CREB1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG 10923:[DB01183 DB11217] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11217|Arbutin TYR;ALB common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0001895| retina homeostasis ALB GO:0044267| cellular protein metabolic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0008152| metabolic process TYR;CES1;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP3A4;TYR;CYP2C8 GO:0043687| post-translational protein modification ALB 10924:[DB01183 DB03541] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process NQO2;CYP2C8;CYP3A4;DHRS4L1 GO:0042493| response to drug ABCB1;UGT1A1;TYMS;CREB1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;NQO2 GO:0045471| response to ethanol OPRM1;UGT1A1;TYMS;OPRK1 GO:0007623| circadian rhythm TYMS;CREB1 GO:0009636| response to toxin CES1;TYMS GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0007568| aging CREB1;TYMS GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS 10925:[DB01183 DB00138] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00138|Cystine SLC7A11;CTNS;SLC7A9;SLC3A1;SLC16A10 common genes common pathways GO:0008542| visual learning CREB1;CTNS GO:0035094| response to nicotine SLC7A11;CREB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC16A10;CTNS GO:0006811| ion transport CTNS;SLCO1A2 GO:0009636| response to toxin SLC7A11;CES1 10926:[DB01183 DB05992] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05992|Plinabulin TNF common genes common pathways GO:0010628| positive regulation of gene expression TLR4;TNF GO:0010033| response to organic substance TNF;CREB1;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;OPRM1 GO:0000187| activation of MAPK activity TLR4;TNF GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0032755| positive regulation of interleukin-6 production TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TNF;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1 GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0006954| inflammatory response TNF;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNF GO:0006955| immune response OPRD1;TLR4;TNF;OPRK1 GO:0010629| negative regulation of gene expression TNF;CREB1;ESR1;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;TNF GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0043491| protein kinase B signaling cascade TNF;CREB1 GO:0042742| defense response to bacterium TNF;TLR4 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;OPRK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;TNF GO:0045672| positive regulation of osteoclast differentiation CREB1;TNF GO:0050727| regulation of inflammatory response TLR4;TNF;ESR1 GO:0043065| positive regulation of apoptotic process CREB1;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:0032729| positive regulation of interferon-gamma production TNF;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0046330| positive regulation of JNK cascade TNF;TLR4 10927:[DB01183 DB01063] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01063|Acetophenazine DRD2;DRD1;AR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0042493| response to drug DRD1;ABCB1;DRD2;CREB1;UGT1A1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0042711| maternal behavior OPRK1;DRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1 GO:0035094| response to nicotine DRD2;CREB1 GO:0008542| visual learning DRD1;CREB1;DRD2 GO:0043278| response to morphine DRD2;OPRK1;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0045471| response to ethanol UGT1A1;DRD2;OPRK1;OPRM1 GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;TLR4;CREB1;DRD2 GO:0007626| locomotory behavior DRD1;OPRM1;DRD2;OPRK1 GO:0048148| behavioral response to cocaine DRD1;DRD2;OPRK1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;OPRM1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0007409| axonogenesis DRD2;CREB1 GO:0009636| response to toxin CES1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TLR4;OPRM1 GO:0042220| response to cocaine DRD1;OPRM1;OPRK1;DRD2 GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression TLR4;DRD1;AR GO:0001666| response to hypoxia CREB1;DRD2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRM1;OPRD1 GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation DRD2;OPRM1;AR GO:0014002| astrocyte development DRD1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;DRD1;OPRK1;DRD2 GO:0007613| memory CREB1;DRD1 GO:0006810| transport AR;ABCB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:1900273| CREB1;DRD2 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;AR;DRD1;CREB1;TLR4;OPRK1;DRD2 10928:[DB01183 DB04310] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways 10929:[DB01183 DB08479] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0007568| aging TYMS;CREB1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0009636| response to toxin TYMS;CES1 GO:0045471| response to ethanol OPRM1;OPRK1;TYMS;UGT1A1 GO:0007623| circadian rhythm CREB1;TYMS GO:0042493| response to drug TYMS;CREB1;UGT1A1;ABCB1 10930:[DB01183 DB01525] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01525|Ecgonine BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0042493| response to drug CREB1;BCHE;UGT1A1;ABCB1 10931:[DB01183 DB11591] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes SLCO1A2 common pathways GO:0008542| visual learning CREB1;HRH1 GO:0006954| inflammatory response HRH1;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;HRH1;OPRM1 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO2B1;ALB GO:0055085| transmembrane transport SLCO2B1;ABCB1;SLCO1A2;ABCB5 GO:0006855| drug transmembrane transport ABCB5;ABCB1 GO:0006811| ion transport SLCO1A2;SLCO2B1 GO:0015711| organic anion transport SLCO1A2 GO:0007165| signal transduction OPRD1;HRH1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0007613| memory CREB1;HRH1 GO:0030154| cell differentiation CREB1;ABCB5 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;HRH1;OPRD1 10932:[DB01183 DB05352] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05352|Fx-1006A TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB GO:0006810| transport TTR;ABCB1 10933:[DB01183 DB06775] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06775|Carglumic acid CPS1 common genes common pathways GO:0032094| response to food OPRM1;CPS1 GO:0042493| response to drug CPS1;CREB1;UGT1A1;ABCB1 GO:0008152| metabolic process CPS1;CES1;UGT1A1 GO:0042594| response to starvation UGT1A1;CPS1 GO:0033762| response to glucagon stimulus CPS1;CREB1 GO:0032496| response to lipopolysaccharide CPS1;OPRM1;UGT1A1;TLR4 GO:0001889| liver development CPS1;UGT1A1 GO:0009636| response to toxin CES1;CPS1 GO:0048545| response to steroid hormone stimulus CPS1;UGT1A1 GO:0051384| response to glucocorticoid stimulus CPS1;UGT1A1 10934:[DB01183 DB05969] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0030855| epithelial cell differentiation CES1;VEGFA GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;VEGFA GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK7 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1;CDK7 GO:0010628| positive regulation of gene expression TLR4;VEGFA GO:0001666| response to hypoxia CREB1;VEGFA GO:0071456| cellular response to hypoxia VEGFA;OPRD1 GO:0030154| cell differentiation VEGFA;CREB1 GO:0006468| protein phosphorylation CDK7;CREB1 GO:0050821| protein stabilization CREB1;CDK7 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;CDK7 GO:0006355| regulation of transcription, DNA-dependent ESR1;CDK7;CREB1 GO:0010629| negative regulation of gene expression VEGFA;OPRD1;ESR1;CREB1 GO:0007595| lactation VEGFA;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter CDK7;ESR1 GO:0006351| transcription, DNA-dependent CREB1;CDK7;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;VEGFA GO:1900745| VEGFA;OPRK1 GO:0060749| mammary gland alveolus development VEGFA;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;ESR1 GO:0043066| negative regulation of apoptotic process ALB;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;CDK7;TLR4;VEGFA;ESR1 GO:0002576| platelet degranulation VEGFA;ALB 10935:[DB01183 DB00809] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;CHRM4;CHRM1;CHRM2;OPRM1;OPRD1 GO:0007165| signal transduction CHRM2;CHRM1;ESR1;OPRD1;OPRM1;TLR4;CREB1;CHRM3;OPRK1;CHRM4 GO:0007586| digestion UGT1A1;CHRM3 10936:[DB01183 DB02047] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;PTGS1 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4 GO:0006954| inflammatory response TLR4;PTGS1 GO:0098869| PTGS1;ALB 10937:[DB01183 DB04879] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;KDR GO:0016032| viral reproduction KDR;CREB1 GO:0046330| positive regulation of JNK cascade TLR4;FLT4 GO:0043066| negative regulation of apoptotic process ALB;KDR;FLT4 GO:0070374| positive regulation of ERK1 and ERK2 cascade KDR;TLR4;FLT4;OPRM1 GO:0030154| cell differentiation KDR;CREB1;FLT1 GO:0006468| protein phosphorylation FLT1;FLT4;CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1;FLT1 10938:[DB01183 DB02303] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;DPYD 10939:[DB01183 DB00004] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0002376| immune system process IL2RA;TLR4 GO:0007165| signal transduction ESR1;IL2RG;OPRD1;OPRM1;TLR4;CREB1;IL2RB;OPRK1 GO:0006954| inflammatory response IL2RA;TLR4 GO:0016032| viral reproduction IL2RG;IL2RB;CREB1 GO:0006955| immune response OPRK1;TLR4;OPRD1;IL2RG;IL2RA GO:0043066| negative regulation of apoptotic process IL2RB;ALB 10940:[DB01183 DB05461] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;HTR2B GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2B;ESR1;OPRD1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TLR4 GO:0042493| response to drug HTR2B;ABCB1;CREB1;UGT1A1 GO:0007610| behavior HTR2B;OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;ADRA2C;ESR1;ADRA2B;HTR2B;OPRK1;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway ADRA2C;ADRA2B;OPRM1;OPRD1;HTR2B;OPRK1 GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1;OPRK1 GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;HTR2B;OPRM1 10941:[DB01183 DB04849] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04849|Cediranib KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR4;KDR GO:0006468| protein phosphorylation CREB1;KDR GO:0030154| cell differentiation KDR;CREB1 GO:0010629| negative regulation of gene expression CREB1;KDR;ESR1;OPRD1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0016032| viral reproduction KDR;CREB1 GO:0043066| negative regulation of apoptotic process KDR;ALB 10942:[DB01183 DB02690] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02690|NU1025 PARP1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;PARP1;ESR1 GO:0006351| transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PARP1;CREB1 GO:1904646| TLR4;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;PARP1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;PARP1 10943:[DB01183 DB02901] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes ESR1;ABCB1 common pathways GO:0030879| mammary gland development CYP19A1;CREB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination AR;ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP17A1;CYP2C8;CYP3A4;CYP11A1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0032355| response to estradiol stimulus ESR1 GO:0006810| transport AR;ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction AR;OPRD1;OPRM1;ESR1;OPRK1;NR3C2;TLR4;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;NR3C2;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process HSD17B1;CYP11A1;CYP3A4;CYP2C8;CYP17A1;CYP19A1 GO:2001225| regulation of chloride transport ABCB1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0008210| estrogen metabolic process HSD17B1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C2;AR;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:1901529| ABCB1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;NR3C2;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway NR3C2;ESR1;AR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0060065| uterus development ESR1;CYP19A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;AR GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0006629| lipid metabolic process HSD17B1;CYP11A1;CYP3A4 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR 10944:[DB01183 DB00163] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00163|Vitamin E NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;SEC14L4;SEC14L3;SEC14L2;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0045471| response to ethanol GSTP1;OPRK1;UGT1A1;NQO1;OPRM1;SOD1 GO:0097190| apoptotic signaling pathway PRKCA;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PRKCB;HMOX1;TLR4 GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0006351| transcription, DNA-dependent NR1I2;CREB1;ESR1;PRKCB;SEC14L2 GO:0002576| platelet degranulation ALB;SOD1 GO:0043065| positive regulation of apoptotic process CREB1;HMOX1;SOD1 GO:0007626| locomotory behavior OPRK1;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;NR1I2;TLR4 GO:0071222| cellular response to lipopolysaccharide GSTP1;OPRK1;TLR4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;NR1I2;NQO1;CYP2C8;GSTP1 GO:0008152| metabolic process DGKA;CES1;GSTA2;GSTO1;GSTP1;UGT1A1;GSTM3 GO:0043066| negative regulation of apoptotic process GCLC;SOD1;ALB;GSTP1;NQO1 GO:0006629| lipid metabolic process CYP3A4;TTPA GO:0071260| cellular response to mechanical stimulus GCLC;TLR4 GO:0042493| response to drug SOD1;ABCB1;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NR1I2 GO:0006355| regulation of transcription, DNA-dependent PPP2CA;CREB1;NR1I2;SEC14L2;PRKCB;ESR1 GO:0043086| negative regulation of catalytic activity UGT1A1;NQO1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;SEC14L2;NR1I2;CREB1 GO:0055114| oxidation-reduction process NQO1;CYP2C8;HMOX1;GSTO1;CYP3A4;SOD1;ALOX5 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;PRKCB GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0006954| inflammatory response TLR4;ALOX5 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0035094| response to nicotine CREB1;HMOX1 GO:0032355| response to estradiol stimulus ESR1;NQO1;GSTP1 GO:0008202| steroid metabolic process CYP3A4;NR1I2;UGT1A1;CYP2C8 GO:0042167| heme catabolic process HMOX1;UGT1A1 GO:0006468| protein phosphorylation CREB1;PRKCA;PRKCB GO:0071456| cellular response to hypoxia OPRD1;HMOX1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0007568| aging NQO1;CREB1;SOD1;GCLC GO:0006810| transport ABCB1;TTPA GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0002376| immune system process TLR4;PRKCB GO:0032720| negative regulation of tumor necrosis factor production GSTP1;TLR4 GO:0098869| GSTO1;GSTP1;ALB GO:0035729| cellular response to hepatocyte growth factor stimulus GCLC;CREB1 GO:0030111| regulation of Wnt receptor signaling pathway PPP2CA;ESR1 GO:0007165| signal transduction PRKCB;ESR1;OPRD1;OPRM1;OPRK1;NR1I2;TLR4;CREB1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0009636| response to toxin GSTP1;TTPA;NQO1;CES1 GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PRKCA GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0000187| activation of MAPK activity SOD1;TLR4 GO:0030855| epithelial cell differentiation GSTA2;CES1 GO:0001895| retina homeostasis ALB;SOD1 GO:0010628| positive regulation of gene expression TLR4;NR1I2 GO:0001666| response to hypoxia PRKCB;HMOX1;CREB1 GO:0043627| response to estrogen stimulus OPRK1;GSTM3;HMOX1;ESR1 GO:0007584| response to nutrient NQO1;TTPA;UGT1A1;GCLC GO:0007411| axon guidance CREB1;PRKCA GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;HMOX1 GO:0010033| response to organic substance CREB1;UGT1A1;PPP2CA;SOD1 GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1 GO:0014823| response to activity GCLC;CREB1 10945:[DB01183 DB03910] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03910|S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation NOS3;OPRM1 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS3 10946:[DB01183 DB06202] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes ESR1 common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0006954| inflammatory response TLR4;CNR2 GO:0006955| immune response OPRD1;CNR2;TLR4;OPRK1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;CREB1;TLR4;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;OPRK1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0006351| transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR2;OPRK1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CNR2 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;CNR2;OPRD1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0007165| signal transduction ESR1;OPRM1;CNR2;OPRD1;CREB1;TLR4;ESR2;OPRK1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;ESR2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0032355| response to estradiol stimulus ESR1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;OPRK1 10947:[DB01183 DB08798] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08798|Sulfamoxole CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 10948:[DB01183 DB05905] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05905|TD-2749 HTR4 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;HTR4;OPRD1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;ESR1;OPRD1;OPRM1;HTR4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;HTR4;OPRK1 GO:0007268| synaptic transmission OPRD1;HTR4;OPRM1;OPRK1 10949:[DB01183 DB04070] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04070|6-Deoxyerythronolide B CYP3A4 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 10950:[DB01183 DB00807] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00807|Proparacaine SCN10A common genes common pathways GO:0019233| sensory perception of pain OPRD1;OPRM1;SCN10A;OPRK1 GO:0007600| sensory perception SCN10A;OPRK1;OPRM1 GO:0006811| ion transport SLCO1A2;SCN10A GO:0055085| transmembrane transport SLCO1A2;ABCB1;SCN10A 10951:[DB01183 DB01972] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;DLG4;ESR1 GO:0007165| signal transduction PDE5A;TLR4;CREB1;OPRK1;OPRD1;OPRM1;HINT1;ESR1;DLG4 GO:0031100| organ regeneration ATIC;UGT1A1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;DLG4 GO:0006351| transcription, DNA-dependent HINT1;ESR1;CREB1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity DLG4;OPRM1 GO:0008152| metabolic process CES1;ATIC;UGT1A1;PDE5A GO:0055114| oxidation-reduction process CYP2C8;GMPR;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;HINT1 GO:0007268| synaptic transmission DLG4;OPRM1;OPRD1;OPRK1 10952:[DB01183 DB01217] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes CYP3A4 common pathways GO:0002933| CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C9;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C9;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP19A1;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4;CES1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP1A2 GO:0060065| uterus development ESR1;CYP19A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 10953:[DB01183 DB05662] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05662|NP-50301 ESR1 common genes ESR1 common pathways GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:1903799| ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;OPRK1 GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0060065| uterus development ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;OPRK1 10954:[DB01183 DB05511] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05511|Piclidenoson ADORA3 common genes common pathways GO:0007165| signal transduction OPRK1;ADORA3;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway ADORA3;OPRK1;OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation ADORA3;OPRM1 GO:0006954| inflammatory response TLR4;ADORA3 10955:[DB01183 DB06879] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;NOS2;TLR4;UGT1A1 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;NOS2 GO:0010629| negative regulation of gene expression NOS2;CREB1;OPRD1;ESR1 GO:0009617| response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;NOS2 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0001666| response to hypoxia CREB1;NOS2 10956:[DB01183 DB07637] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07637|Dibromotyrosine EPOR common genes common pathways GO:0007165| signal transduction OPRK1;CREB1;TLR4;ESR1;EPOR;OPRM1;OPRD1 10957:[DB01183 DB06791] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes CYP3A4 common pathways GO:0008285| negative regulation of cell proliferation SSTR2;SSTR5;OPRM1 GO:0007584| response to nutrient UGT1A1;SSTR2 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger SSTR5;OPRD1;OPRM1;SSTR2 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0007165| signal transduction CREB1;TLR4;SSTR2;OPRK1;ESR1;OPRM1;OPRD1;SSTR5 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;SSTR2;OPRK1 GO:0071392| cellular response to estradiol stimulus ESR1;SSTR2;UGT1A1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;SSTR5;SSTR2;OPRK1 GO:0071385| cellular response to glucocorticoid stimulus SSTR5;SSTR2;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0007268| synaptic transmission SSTR5;OPRD1;OPRM1;OPRK1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0007586| digestion SSTR2;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0042594| response to starvation UGT1A1;SSTR2 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8 GO:0007218| neuropeptide signaling pathway SSTR2;OPRK1;OPRM1;OPRD1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 10958:[DB01183 DB03158] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;INPP5B;CREB1;TLR4;OPRK1 10959:[DB01183 DB05202] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways GO:0002576| platelet degranulation VWF;ALB 10960:[DB01183 DB01622] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes ALB common pathways GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD1 GO:0048148| behavioral response to cocaine DRD2;OPRK1;HTR2A;DRD1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0007626| locomotory behavior DRD2;OPRK1;DRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;HTR2A GO:0045471| response to ethanol OPRM1;DRD2;OPRK1;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;OPRM1;OPRD1;ESR1;HTR2A;ADRA1A;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;OPRM1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0008542| visual learning DRD2;CREB1;DRD1 GO:0043278| response to morphine OPRK1;DRD2;OPRM1 GO:0035094| response to nicotine DRD2;CREB1 GO:0016032| viral reproduction CREB1;HTR2A GO:0042711| maternal behavior DRD1;OPRK1 GO:0043687| post-translational protein modification ALB GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0007268| synaptic transmission HTR2A;OPRD1;OPRM1;OPRK1 GO:0042493| response to drug HTR2A;DRD1;CREB1;UGT1A1;DRD2;ADRA1A;ABCB1 GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0007165| signal transduction OPRM1;OPRD1;HTR1A;ESR1;HTR2A;ADRA1B;DRD1;CREB1;TLR4;ADRA1A;DRD2;OPRK1 GO:1900273| CREB1;DRD2 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0007568| aging HTR2A;CREB1;ADRA1A GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0043069| negative regulation of programmed cell death ALB GO:0007613| memory CREB1;HTR2A;DRD1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1B;OPRM1;ESR1;HTR2A GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0014002| astrocyte development DRD1;TLR4 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway HTR1A;HTR2A;OPRM1;OPRD1;ADRA1B;DRD1;OPRK1;DRD2;ADRA1A GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;DRD1 GO:0001666| response to hypoxia DRD2;CREB1 GO:0010628| positive regulation of gene expression TLR4;DRD1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0001895| retina homeostasis ALB GO:0042220| response to cocaine OPRK1;DRD2;DRD1;OPRM1 GO:0044267| cellular protein metabolic process ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;DRD2;ADRA1A;TLR4 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 10961:[DB01183 DB00693] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00693|Fluorescein CYP1A1;SLC22A6;ABCB11;ABCC1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;ABCC1;CREB1;CYP1A1 GO:0032094| response to food CYP1A1;OPRM1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;CYP1A1;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1 GO:0002933| CYP1A1;CYP2C8;CYP3A4 GO:0009636| response to toxin CYP1A1;CES1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB11;SLCO1A2;SLC22A6;ABCC1;ABCB1 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;ALB GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0010033| response to organic substance CYP1A1;CREB1;UGT1A1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLCO1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP2C8;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0007568| aging CYP1A1;CREB1 GO:0006810| transport ABCB1;ABCC1;ABCB11 GO:0017144| drug metabolic process CYP1A1;UGT1A1;CYP2C8;CYP3A4 GO:0097267| CYP1A1;CYP2C8 GO:0015711| organic anion transport SLC22A6;SLCO1A2 10962:[DB01183 DB05188] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05188|KD3010 PPARD common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARD;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;ESR1;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;ESR1 GO:0097190| apoptotic signaling pathway PPARD;TLR4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARD;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARD GO:0042060| wound healing OPRM1;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARD GO:0006629| lipid metabolic process PPARD;CYP3A4 GO:0071222| cellular response to lipopolysaccharide PPARD;TLR4;OPRK1 GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0014823| response to activity CREB1;PPARD GO:0010033| response to organic substance PPARD;CREB1;UGT1A1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARD GO:0010628| positive regulation of gene expression TLR4;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD GO:0030154| cell differentiation PPARD;CREB1 10963:[DB01183 DB05767] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0007568| aging NFKB2;CREB1 GO:0051384| response to glucocorticoid stimulus IL6;TNF;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;TNF;OPRD1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;NFKB1;NFKB2;TLR4;CREB1;IL1B;OPRK1 GO:0032722| positive regulation of chemokine production TLR4;TNF;IL6 GO:0032757| positive regulation of interleukin-8 production TNF;TLR4;IL1B GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TNF;TLR4;IL1B GO:0032715| negative regulation of interleukin-6 production TLR4;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;NFKB2;TLR4;NFKB1 GO:0032755| positive regulation of interleukin-6 production IL1B;IL6;TNF;TLR4 GO:0006366| transcription from RNA polymerase II promoter CREB1;NFKB2;ESR1;NFKB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TLR4;OPRM1 GO:0000187| activation of MAPK activity IL1B;TNF;TLR4 GO:0044267| cellular protein metabolic process ALB;IL6 GO:0048511| rhythmic process NFKB2;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;IL1B;IL6 GO:0010033| response to organic substance TNF;CREB1;UGT1A1 GO:0010628| positive regulation of gene expression TLR4;TNF;IL1B;IL6 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0097190| apoptotic signaling pathway TLR4;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF;IL1B GO:0046330| positive regulation of JNK cascade IL1B;TNF;TLR4 GO:0006351| transcription, DNA-dependent NFKB1;ESR1;CREB1;NFKB2 GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;ESR1 GO:0032496| response to lipopolysaccharide NFKB2;TLR4;UGT1A1;IL1B;OPRM1 GO:0032729| positive regulation of interferon-gamma production IL1B;TNF;TLR4 GO:0045087| innate immune response TLR4;NFKB2;NFKB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NFKB1;TNF;NFKB2 GO:1900745| IL1B;OPRK1 GO:0071260| cellular response to mechanical stimulus TLR4;IL1B;NFKB1 GO:0043065| positive regulation of apoptotic process CREB1;TNF;IL6 GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0050727| regulation of inflammatory response ESR1;TLR4;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IL6;NFKB2;TLR4;TNF;CREB1;NFKB1;ESR1 GO:0071222| cellular response to lipopolysaccharide TNF;TLR4;OPRK1;IL6;NFKB1 GO:0050829| defense response to Gram-negative bacterium TLR4;IL6 GO:0042346| positive regulation of NF-kappaB import into nucleus IL1B;TLR4;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TNF;IL1B GO:0043066| negative regulation of apoptotic process IL6;ALB;NFKB1 GO:0042742| defense response to bacterium TNF;TLR4 GO:0043491| protein kinase B signaling cascade IL1B;TNF;CREB1 GO:0043687| post-translational protein modification ALB;IL6 GO:0010629| negative regulation of gene expression CREB1;TNF;ESR1;OPRD1;NFKB1 GO:0051607| defense response to virus IL6;OPRK1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;ESR1;NFKB2;CREB1 GO:0045416| positive regulation of interleukin-8 biosynthetic process TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;NFKB1;TNF;CREB1;IL6;IL1B GO:0006953| acute-phase response UGT1A1;IL6 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;NFKB2;TLR4;IL6;IL1B;NFKB1 GO:0006954| inflammatory response TNF;NFKB2;TLR4;IL1B;IL6;NFKB1 GO:0006955| immune response OPRD1;TNF;TLR4;IL6;IL1B;OPRK1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;IL6;IL1B;TNF 10964:[DB01183 DB06820] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C8;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2D6 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;CYP1A2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2D6;CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2C8;CYP2D6;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP2C8;CYP2C9 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2D6;CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C9;CYP2C8 10965:[DB01183 DB00933] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0048148| behavioral response to cocaine OPRK1;DRD2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;CREB1;TLR4;ESR1 GO:0007626| locomotory behavior DRD2;OPRK1;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0019233| sensory perception of pain OPRK1;HTR2A;OPRM1;OPRD1 GO:0045471| response to ethanol OPRM1;OPRK1;DRD2;UGT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A;OPRK1 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0043278| response to morphine OPRM1;DRD2;OPRK1 GO:0008542| visual learning DRD2;CREB1 GO:0035094| response to nicotine DRD2;CREB1 GO:0016032| viral reproduction HTR2A;CREB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C8 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0042493| response to drug CREB1;UGT1A1;DRD2;ABCB1;HTR2A GO:0007268| synaptic transmission OPRM1;OPRD1;HTR2A;OPRK1 GO:0007610| behavior HTR2A;OPRK1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2D6;UGT1A1 GO:0007165| signal transduction ESR1;HTR2A;OPRM1;OPRD1;OPRK1;DRD2;CREB1;TLR4 GO:1900273| CREB1;DRD2 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C8 GO:0007568| aging HTR2A;CREB1 GO:0040018| positive regulation of multicellular organism growth DRD2;CREB1 GO:0007613| memory HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;OPRM1;OPRD1;OPRK1;DRD2 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0001666| response to hypoxia DRD2;CREB1 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0042220| response to cocaine OPRM1;OPRK1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;OPRM1;DRD2;TLR4 GO:0009636| response to toxin DRD2;CES1 GO:0007409| axonogenesis DRD2;CREB1 10966:[DB01183 DB00069] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00069|Interferon alfacon-1 IFNAR1;IFNAR2 common genes common pathways GO:0051607| defense response to virus IFNAR2;OPRK1 GO:0032496| response to lipopolysaccharide IFNAR1;OPRM1;TLR4;UGT1A1 10967:[DB01183 DB13869] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes ESR1 common pathways GO:0007165| signal transduction ESR2;OPRK1;CREB1;TLR4;ESR1;OPRM1;OPRD1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;ESR2 GO:0006338| chromatin remodeling ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;TLR4;CREB1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060065| uterus development ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0060068| vagina development ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 10968:[DB01183 DB08143] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08143|5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE F10 common genes common pathways 10969:[DB01183 DB02820] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HSD17B10 GO:0055114| oxidation-reduction process CYP2C8;HSD17B10;CYP3A4 10970:[DB01183 DB09498] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09498|Strontium chloride Sr-89 ALPPL2;ALPL;SLC8A1;CACNA1I common genes common pathways GO:0055085| transmembrane transport ABCB1;CACNA1I;SLC8A1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLC8A1;CACNA1I GO:0007584| response to nutrient SLC8A1;UGT1A1 GO:0001666| response to hypoxia CREB1;SLC8A1 GO:0071456| cellular response to hypoxia OPRD1;SLC8A1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;SLC8A1 GO:0006810| transport ABCB1;CACNA1I GO:0051384| response to glucocorticoid stimulus ALPL;UGT1A1 GO:0007165| signal transduction CACNA1I;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0070588| calcium ion transmembrane transport OPRM1;SLC8A1;CACNA1I GO:0042493| response to drug SLC8A1;UGT1A1;CREB1;ABCB1 GO:0051924| regulation of calcium ion transport OPRD1;SLC8A1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;SLC8A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ALPL;OPRM1 GO:0008152| metabolic process CES1;ALPL;ALPPL2;UGT1A1 10971:[DB01183 DB00223] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00223|Diflorasone NR3C1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;NR3C1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;NR3C1;ESR1;OPRK1;CREB1;TLR4 10972:[DB01183 DB02481] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02481|N-Benzylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;ADH1B;CYP3A4 10973:[DB01183 DB00106] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00106|Abarelix GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GNRHR;OPRD1;OPRM1 GO:0007165| signal transduction OPRK1;GNRHR;TLR4;CREB1;OPRD1;OPRM1;ESR1 10974:[DB01183 DB14514] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14514|Magnesium levulinate ATP1A1 common genes common pathways GO:0006811| ion transport ATP1A1;SLCO1A2 GO:0042493| response to drug ATP1A1;UGT1A1;CREB1;ABCB1 GO:0071260| cellular response to mechanical stimulus TLR4;ATP1A1 10975:[DB01183 DB04278] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways GO:0030890| positive regulation of B cell proliferation IL2;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;IL2;OPRK1 GO:0050729| positive regulation of inflammatory response TLR4;IL2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1;IL2 GO:0002376| immune system process TLR4;IL2 GO:0006955| immune response TLR4;IL2;OPRK1;OPRD1 GO:0032729| positive regulation of interferon-gamma production IL2;TLR4 GO:0045471| response to ethanol IL2;OPRK1;UGT1A1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;IL2;ESR1 GO:0043066| negative regulation of apoptotic process ALB;IL2 10976:[DB01183 DB04787] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04787|Tanaproget PGR common genes common pathways GO:0030879| mammary gland development PGR;CREB1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;PGR;TLR4;CREB1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;PGR;CREB1 GO:0006355| regulation of transcription, DNA-dependent PGR;CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PGR GO:0006351| transcription, DNA-dependent ESR1;CREB1;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;CREB1;TLR4;ESR1 10977:[DB01183 DB07001] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07001|(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 GO:0055114| oxidation-reduction process CYP2C8;NOS3;CYP3A4 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 10978:[DB01183 DB01116] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0006811| ion transport CHRNA10;SLCO1A2 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;OPRM1;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007165| signal transduction OPRK1;CHRNA10;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0070588| calcium ion transmembrane transport OPRM1;CHRNA10 GO:0042493| response to drug ABCB1;BCHE;UGT1A1;CREB1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA10;OPRM1 10979:[DB01183 DB00729] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00729|Diphemanil Methylsulfate CHRM3 common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;CHRM3;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;OPRK1;OPRD1;OPRM1 GO:0007586| digestion CHRM3;UGT1A1 10980:[DB01183 DB09086] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09086|Eugenol ESR1;ESR2;AR;TRPV3 common genes ESR1 common pathways GO:0032355| response to estradiol stimulus ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus ESR2;UGT1A1;ESR1 GO:0006810| transport ABCB1;AR GO:1903799| ESR1 GO:0070588| calcium ion transmembrane transport OPRM1;TRPV3 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0007165| signal transduction CREB1;TLR4;ESR2;OPRK1;ESR1;OPRM1;OPRD1;AR GO:0002064| epithelial cell development ESR1 GO:0006811| ion transport TRPV3;SLCO1A2 GO:0055085| transmembrane transport ABCB1;TRPV3;SLCO1A2 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0008584| male gonad development AR;ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination AR;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1 GO:0006351| transcription, DNA-dependent CREB1;ESR2;ESR1;AR GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;ESR2;TLR4;CREB1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0060065| uterus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;AR;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR2;ESR1;AR GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR2;ESR1;AR GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;AR;ESR1 GO:0048863| stem cell differentiation ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 10981:[DB01183 DB07675] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0042493| response to drug PPARG;CREB1;UGT1A1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm CREB1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;PPARG;TLR4 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0045087| innate immune response PPARG;TLR4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0010033| response to organic substance UGT1A1;CREB1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;PPARG;TLR4;OPRK1 10982:[DB01183 DB05038] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05038|Anatibant BDKRB2 common genes common pathways GO:0006954| inflammatory response TLR4;BDKRB2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;BDKRB2;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;BDKRB2;OPRD1 GO:0007165| signal transduction OPRD1;BDKRB2;OPRM1;ESR1;OPRK1;TLR4;CREB1 10983:[DB01183 DB13975] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2D6;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP2D6;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C8;CYP2C9;UGT1A1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0097267| CYP1A2;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;CYP2D6;UGT1A1;CYP2C9 GO:0070989| oxidative demethylation CYP2C8;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;CREB1;UGT1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 10984:[DB01183 DB06213] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06213|Regadenoson ADORA2A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;ADORA2A GO:0007165| signal transduction OPRK1;ADORA2A;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0042755| eating behavior OPRK1;ADORA2A;OPRD1;OPRM1 GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0051881| regulation of mitochondrial membrane potential OPRD1;ADORA2A GO:0008285| negative regulation of cell proliferation OPRM1;ADORA2A GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA2A;OPRM1 GO:0007626| locomotory behavior OPRM1;ADORA2A;OPRK1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ADORA2A;CREB1 GO:0042493| response to drug UGT1A1;CREB1;ADORA2A;ABCB1 GO:0006954| inflammatory response TLR4;ADORA2A GO:0007600| sensory perception OPRK1;ADORA2A;OPRM1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A 10985:[DB01183 DB09327] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP3A4;CYP2A6;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2A6;CYP3A4 GO:0042493| response to drug CREB1;TYMS;UGT1A1;ABCB1 GO:0007595| lactation CREB1;SLC29A1 GO:0045471| response to ethanol OPRK1;UGT1A1;TYMS;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;OPRM1 GO:0007623| circadian rhythm TYMS;CREB1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2A6 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC22A7 GO:0006811| ion transport SLC22A7;SLCO1A2 GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0009636| response to toxin TYMS;CES1 GO:0071456| cellular response to hypoxia OPRD1;SLC29A1 GO:0007568| aging TYMS;CREB1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A7;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2A6;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2A6;UGT1A1;CYP2C8 GO:0015711| organic anion transport SLC22A7;SLCO1A2 10986:[DB01183 DB00042] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways GO:0030154| cell differentiation CREB1;SYT2 10987:[DB01183 DB08386] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0007165| signal transduction OPRK1;TLR4;CREB1;PDE10A;ESR1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway PDE10A;OPRD1;OPRM1;OPRK1 GO:0008152| metabolic process UGT1A1;PDE10A;CES1 10988:[DB01183 DB00891] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00891|Sulfapyridine CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0097267| CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 10989:[DB01183 DB04655] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04655|Metoprine HNMT common genes common pathways 10990:[DB01183 DB08744] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;NQO2;CYP3A4;CES1 GO:0055114| oxidation-reduction process CYP2C8;NQO2;CYP3A4 10991:[DB01183 DB04253] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04253|Tretazicar NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process NQO2;CYP2C8;CES1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;NQO2;CYP3A4 10992:[DB01183 DB06314] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06314|SGX-523 MET common genes common pathways GO:0006468| protein phosphorylation MET;CREB1 GO:0007165| signal transduction OPRD1;OPRM1;MET;ESR1;OPRK1;TLR4;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;MET 10993:[DB01183 DB06246] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06246|Exisulind PDE4D;PDE4C;PDE5A;PDE2A;GSTP1;AKR1B1;AKR1B10 common genes common pathways GO:0009636| response to toxin GSTP1;CES1 GO:0070373| negative regulation of ERK1 and ERK2 cascade TLR4;GSTP1 GO:0010033| response to organic substance CREB1;AKR1B1;UGT1A1 GO:0007568| aging PDE4D;CREB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;AKR1B10;UGT1A1 GO:0050729| positive regulation of inflammatory response TLR4;PDE2A GO:0007186| G-protein coupled receptor signaling pathway OPRM1;PDE4D;OPRD1;PDE2A;PDE4C;OPRK1 GO:0032355| response to estradiol stimulus GSTP1;ESR1 GO:0007165| signal transduction ESR1;OPRM1;PDE4D;OPRD1;PDE4C;OPRK1;CREB1;TLR4;PDE5A;PDE2A GO:0098869| GSTP1;ALB GO:0070588| calcium ion transmembrane transport PDE2A;OPRM1 GO:0032720| negative regulation of tumor necrosis factor production TLR4;GSTP1 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;AKR1B10;AKR1B1;CYP2C8 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;GSTP1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade GSTP1;ESR1 GO:0032729| positive regulation of interferon-gamma production TLR4;PDE4D GO:0071260| cellular response to mechanical stimulus TLR4;PDE2A GO:0007586| digestion AKR1B10;UGT1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;ESR1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB;GSTP1 GO:0071560| cellular response to transforming growth factor beta stimulus PDE2A;CREB1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C8;CYP3A4;CES1 GO:0008152| metabolic process CES1;GSTP1;UGT1A1;PDE5A;PDE2A GO:0071222| cellular response to lipopolysaccharide OPRK1;GSTP1;TLR4;PDE4D 10994:[DB01183 DB11811] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11811|Arhalofenate PPARG common genes common pathways GO:0045087| innate immune response TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;TLR4;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;CREB1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042493| response to drug ABCB1;PPARG;CREB1;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;PPARG;OPRK1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRM1;OPRD1 GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process CREB1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance PPARG;CREB1;UGT1A1 GO:0045600| positive regulation of fat cell differentiation PPARG;CREB1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 10995:[DB01183 DB05246] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05246|Methsuximide CACNA1G;CYP2C19 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0007268| synaptic transmission CACNA1G;OPRK1;OPRM1;OPRD1 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0006811| ion transport CACNA1G;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;CACNA1G GO:0070588| calcium ion transmembrane transport CACNA1G;OPRM1 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C19;UGT1A1 10996:[DB01183 DB05259] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05259|Glatiramer HLA-DRB1 common genes common pathways GO:0006955| immune response OPRD1;OPRK1;HLA-DRB1;TLR4 GO:0042088| T-helper 1 type immune response HLA-DRB1;TLR4 GO:0002376| immune system process HLA-DRB1;TLR4 GO:0032689| negative regulation of interferon-gamma production HLA-DRB1;TLR4 10997:[DB01183 DB07385] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07385|3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE NQO1 common genes common pathways GO:0007584| response to nutrient NQO1;UGT1A1 GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0009636| response to toxin NQO1;CES1 GO:0032355| response to estradiol stimulus NQO1;ESR1 GO:0007568| aging CREB1;NQO1 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 GO:0055114| oxidation-reduction process NQO1;CYP2C8;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;NQO1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;NQO1;CYP2C8 GO:0045471| response to ethanol OPRK1;NQO1;UGT1A1;OPRM1 10998:[DB01183 DB11254] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0048511| rhythmic process CREB1;TOP1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0050729| positive regulation of inflammatory response TGM2;TLR4 GO:0016032| viral reproduction TOP1;CREB1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;TYR GO:0042493| response to drug UGT1A1;CREB1;ABCB1;TOP1 GO:0043065| positive regulation of apoptotic process CREB1;TGM2 GO:0008152| metabolic process UGT1A1;CES1;TYR GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TGM2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger TGM2;OPRM1;OPRD1;ESR1;OPRK1 GO:0007623| circadian rhythm TOP1;CREB1 10999:[DB01183 DB14700] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;F8 GO:0006953| acute-phase response F8;UGT1A1 GO:0002576| platelet degranulation ALB;F8 11000:[DB01183 DB01158] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;TLR4 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;ATP1A1 GO:0006811| ion transport SLCO1A2;ATP1A1 11001:[DB01183 DB06752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06752|Chymopapain PRG2 common genes common pathways GO:0002376| immune system process TLR4;PRG2 GO:0042742| defense response to bacterium TLR4;PRG2 GO:0006955| immune response PRG2;OPRD1;OPRK1;TLR4 11002:[DB01183 DB09095] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0036378| CYP3A4 GO:0031100| organ regeneration UGT1A1;ANXA3 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0007165| signal transduction OPRM1;NR3C1;OPRD1;ESR1;OPRK1;CREB1;TLR4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0051384| response to glucocorticoid stimulus ANXA3;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ANXA3;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR3C1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR3C1;CREB1 GO:0043086| negative regulation of catalytic activity ANXA3;UGT1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042742| defense response to bacterium ANXA3;TLR4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0070848| response to growth factor stimulus OPRM1;ANXA3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1;TLR4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0071560| cellular response to transforming growth factor beta stimulus NR3C1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;ESR1;CREB1 11003:[DB01183 DB02386] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02386|Leucine Phosphonic Acid LAP3 common genes common pathways 11004:[DB01183 DB07903] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07903|3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE METAP1 common genes common pathways 11005:[DB01183 DB06558] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways GO:0051930| regulation of sensory perception of pain OPRK1;EDNRB;OPRD1;OPRM1 GO:0014070| response to organic cyclic compound EDNRB;UGT1A1 GO:0001666| response to hypoxia CREB1;EDNRA GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;EDNRB;ESR1;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1;EDNRA GO:0007568| aging CREB1;EDNRB GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;EDNRB;EDNRA GO:0007165| signal transduction ESR1;OPRM1;OPRD1;EDNRB;OPRK1;EDNRA;CREB1;TLR4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRM1;OPRD1;OPRK1;EDNRB GO:0019233| sensory perception of pain OPRD1;OPRM1;OPRK1;EDNRB GO:0032496| response to lipopolysaccharide EDNRB;UGT1A1;TLR4;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;EDNRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;EDNRB GO:0071222| cellular response to lipopolysaccharide TLR4;EDNRB;OPRK1 GO:0043066| negative regulation of apoptotic process ALB;EDNRB 11006:[DB01183 DB13915] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways 11007:[DB01183 DB05793] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05793|PRO-542 FFAR4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;FFAR4 GO:0007165| signal transduction ESR1;FFAR4;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0032870| cellular response to hormone stimulus UGT1A1;FFAR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;FFAR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;FFAR4 11008:[DB01183 DB00387] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 GO:0007165| signal transduction CHRM1;ESR1;CHRM2;OPRM1;OPRD1;CREB1;TLR4;CHRM3;OPRK1;CHRM4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CHRM1;CHRM2;CHRM4;OPRK1;CHRM3 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;CHRM2 11009:[DB01183 DB05133] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05133|VP025 IL1B common genes common pathways GO:0006955| immune response IL1B;OPRK1;TLR4;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;IL1B GO:0006954| inflammatory response TLR4;IL1B GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;IL1B GO:0043491| protein kinase B signaling cascade IL1B;CREB1 GO:0042346| positive regulation of NF-kappaB import into nucleus IL1B;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway IL1B;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;TLR4;CREB1;ESR1 GO:1900745| IL1B;OPRK1 GO:0071260| cellular response to mechanical stimulus TLR4;IL1B GO:0032729| positive regulation of interferon-gamma production TLR4;IL1B GO:0032496| response to lipopolysaccharide IL1B;TLR4;UGT1A1;OPRM1 GO:0046330| positive regulation of JNK cascade IL1B;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;TLR4 GO:0010628| positive regulation of gene expression TLR4;IL1B GO:0008285| negative regulation of cell proliferation OPRM1;IL1B GO:0000187| activation of MAPK activity TLR4;IL1B GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4;IL1B GO:0032755| positive regulation of interleukin-6 production TLR4;IL1B GO:0032757| positive regulation of interleukin-8 production IL1B;TLR4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;TLR4;CREB1;IL1B;OPRK1 11010:[DB01183 DB01235] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0007623| circadian rhythm DDC;CREB1 GO:0042060| wound healing DRD5;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0045471| response to ethanol OPRK1;DRD2;DRD3;UGT1A1;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0007626| locomotory behavior DRD3;DRD2;OPRK1;OPRM1;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;DRD3;DRD2 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;DRD5;DRD1;OPRM1 GO:0048148| behavioral response to cocaine DRD3;DRD2;OPRK1;DRD4;DRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;DRD3 GO:0007586| digestion UGT1A1;SLC15A1 GO:0042493| response to drug DRD1;ABCB1;DRD2;CREB1;DRD3;UGT1A1 GO:0007268| synaptic transmission OPRK1;DRD5;OPRD1;OPRM1 GO:0048149| behavioral response to ethanol OPRM1;DRD4;DRD2 GO:0042711| maternal behavior DRD1;OPRK1 GO:0042752| regulation of circadian rhythm CREB1;DRD4 GO:0008542| visual learning CREB1;DRD3;DRD2;DRD1 GO:0043278| response to morphine DRD2;OPRK1;DRD3;OPRM1 GO:0035094| response to nicotine DRD2;CREB1 GO:0071363| cellular response to growth factor stimulus DDC;OPRD1;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;DRD4;DRD5;DRD1;DRD3;DRD2;OPRK1 GO:0014002| astrocyte development DRD1;TLR4 GO:0007613| memory CREB1;DRD1 GO:0030154| cell differentiation SLC7A5;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;DRD2 GO:0006810| transport SLC15A1;SLC7A5;ABCB1;SLC7A8 GO:1900273| CREB1;DRD2 GO:0007165| signal transduction TLR4;DRD3;CREB1;DRD2;OPRK1;OPRD1;OPRM1;ESR1;DRD4;DRD5;DRD1 GO:0006811| ion transport SLCO1A2;SLC15A1 GO:0007409| axonogenesis CREB1;DRD2 GO:0009636| response to toxin DDC;SLC7A8;CES1;DRD2 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO1A2;SLC16A10 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;DRD2 GO:0008344| adult locomotory behavior OPRD1;DRD4 GO:0042220| response to cocaine OPRM1;DRD1;DRD5;DRD3;OPRK1;DRD2 GO:0000187| activation of MAPK activity DRD4;TLR4 GO:0001666| response to hypoxia DRD2;CREB1 GO:0010628| positive regulation of gene expression DRD1;TLR4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRM1;OPRD1 GO:0048511| rhythmic process CREB1;DRD4 GO:0008285| negative regulation of cell proliferation DRD2;OPRM1 11011:[DB01183 DB03742] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03742|Compound 4-D ESR1 common genes ESR1 common pathways GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;OPRK1 GO:0002064| epithelial cell development ESR1 GO:0032355| response to estradiol stimulus ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRM1;OPRD1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1 11012:[DB01183 DB02709] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes ALB;ESR1;CYP3A4 common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;AKT1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;AKT1;OPRD1;MTNR1A;OPRK1;PPARG;MTNR1B;APP GO:0051659| maintenance of mitochondrion location ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0050729| positive regulation of inflammatory response TLR4;SNCA GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP1A2;NR1I2;CYP1A1;UGT1A1;CYP2C8;CYP1B1 GO:0006468| protein phosphorylation APP;CREB1;AKT1;CSNK2A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0007613| memory PTGS2;ITGA5;CREB1;APP GO:0030154| cell differentiation CREB1;AKT1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;APP GO:0071456| cellular response to hypoxia PTGS2;OPRD1;AKT1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRK1;OPRM1;OPRD1 GO:0007568| aging AKT1;PTGS2;CREB1;CYP1A1;SNCA GO:0042908| xenobiotic transport SLC2A1;NR1I2;ABCB1 GO:0006810| transport ABCB1;TTR GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0031100| organ regeneration UGT1A1;PPARG GO:1903799| ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:1900273| CREB1;APP GO:0098869| ALB;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;AKT1;ESR1;APP;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0007249| I-kappaB kinase/NF-kappaB cascade AKT1;TLR4 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0017144| drug metabolic process CYP2C8;CYP1A1;UGT1A1;CBR1;CYP3A4;CYP1A2 GO:0097267| CYP2C8;CYP1B1;CYP1A1;CYP1A2 GO:0033138| positive regulation of peptidyl-serine phosphorylation SNCA;APP;OPRD1;AKT1;PTGS2 GO:0007165| signal transduction NR1I3;OPRD1;AKT1;CSNK2A1;OPRM1;ESR1;YARS;OPRK1;MTNR1A;MTNR1B;NR1I2;TLR4;PPARG;CREB1 GO:0002064| epithelial cell development ESR1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;KHSRP GO:0007409| axonogenesis APP;CREB1 GO:0002933| CYP3A4;CYP2C8;CYP1A1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0009636| response to toxin AHR;CYP1A1;CYP1B1;CES1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG;CYP1A1;PTGS2;CYP1A2 GO:0006366| transcription from RNA polymerase II promoter AHR;CREB1;ESR1 GO:0032868| response to insulin stimulus PPARA;SLC2A1;OPRK1 GO:0055085| transmembrane transport ABCB1;SLC2A1;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ALOX15;APP;TLR4 GO:0036378| CYP3A4 GO:0001895| retina homeostasis ALB GO:0008344| adult locomotory behavior OPRD1;APP;SNCA GO:0000187| activation of MAPK activity TLR4;APP GO:0030855| epithelial cell differentiation PPARG;CBR1;CES1 GO:0042220| response to cocaine OPRM1;SNCA;OPRK1 GO:0044267| cellular protein metabolic process APP;ALB;SNCA;TTR GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0008584| male gonad development ESR1 GO:0045600| positive regulation of fat cell differentiation AKT1;PPARG;CREB1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;CREB1;PPARA GO:1904646| TLR4;APP GO:0010628| positive regulation of gene expression APP;TLR4;NR1I2 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger MTNR1B;MTNR1A;OPRD1;OPRM1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;PPARG GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1;AHR;PPARA;CSNK2A1 GO:0010033| response to organic substance CYP1A1;PPARG;CREB1;UGT1A1;CYP1A2;PTGS2;AKT1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;APP GO:1903223| TLR4;APP GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;AHR GO:0007623| circadian rhythm MTNR1B;CREB1;MTNR1A GO:0042060| wound healing ALOX15;ITGB3;PPARA;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2;OPRM1;SNCA;CYP1A1;TLR4;UGT1A1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046889| positive regulation of lipid biosynthetic process CREB1;AKT1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0000060| protein import into nucleus, translocation AKT1;OPRD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;ESR1;OPRD1;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0060079| regulation of excitatory postsynaptic membrane potential SNCA;OPRM1;AKT1 GO:0046330| positive regulation of JNK cascade TLR4;APP GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;AKT1 GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG;NR1I3;PPARA;ESR1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0019233| sensory perception of pain OPRK1;OPRD1;PTGS2;OPRM1 GO:0006351| transcription, DNA-dependent CREB1;PPARG;NR1I2;AHR;KHSRP;PPARA;ESR1;CSNK2A1;NR1I3 GO:0050727| regulation of inflammatory response ESR1;PTGS2;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0043065| positive regulation of apoptotic process CYP1B1;SNCA;APP;PPARG;CREB1;AKT1;PTGS2 GO:0002576| platelet degranulation APP;ALB;ITGB3 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0007626| locomotory behavior OPRK1;APP;OPRM1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;APP;TLR4;NR1I2;CREB1;PPARG;AKT1;NR1I3;PPARA;ESR1 GO:0009314| response to radiation PTGS2;OPRM1;OPRK1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8;CYP1B1;CYP1A1 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;APP GO:0006805| xenobiotic metabolic process CYP2C8;CYP1B1;NR1I2;AHR;NQO2;PTGS1;CYP3A4;CES1;CYP1A2 GO:0060065| uterus development ESR1 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;AKT1 GO:0043066| negative regulation of apoptotic process AKT1;PTGS2;ALB;SNCA GO:0048148| behavioral response to cocaine SNCA;OPRK1 GO:0045087| innate immune response APP;PPARG;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;APP;SNCA;PPARA;ESR1 GO:1990090| APP;CREB1;AKT1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;AKT1;ESR1 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP1A2;CYP3A4;PPARA;ALOX15;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0071260| cellular response to mechanical stimulus TLR4;SLC2A1;AKT1;PTGS2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8;NR1I2 GO:0010629| negative regulation of gene expression APP;CREB1;AKT1;OPRD1;ESR1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;SNCA;MTNR1B;APP GO:0042493| response to drug PTGS2;CYP1A2;UGT1A1;CREB1;PPARG;CYP1A1;ABCB1;SNCA GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARA;NR1I3;CSNK2A1;KHSRP;PPARG;CREB1;NR1I2;AHR GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0032094| response to food CYP1A1;OPRM1;AKT1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARA;AKT1;NR1I2;CREB1;PPARG;AHR GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:1901215| PPARA;AKT1;SNCA;CREB1;APP GO:0043491| protein kinase B signaling cascade CREB1;AKT1 GO:0043687| post-translational protein modification APP;ALB GO:0055114| oxidation-reduction process NQO2;CYP1A1;CYP1B1;CYP2C8;ALOX15;SNCA;PTGS2;CYP1A2;CYP3A4;ALOX5;PTGS1;CBR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TLR4 GO:0006954| inflammatory response PTGS2;AKT1;PTGS1;ALOX5;TLR4;ALOX15 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP;ESR1;AKT1 GO:0016032| viral reproduction ITGA5;CREB1;ITGB3 GO:0001547| antral ovarian follicle growth ESR1 GO:0042752| regulation of circadian rhythm PPARA;PPARG;CREB1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;ESR1;NR1I3;NR1I2;PPARG GO:0071168| protein localization to chromatin ESR1 GO:0008542| visual learning APP;CREB1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 11013:[DB01183 DB01278] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways GO:0001666| response to hypoxia RAMP2;CREB1 GO:0010628| positive regulation of gene expression TLR4;RAMP3;CALCR;RAMP2 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;CALCR;RAMP3;TLR4 GO:0032870| cellular response to hormone stimulus RAMP2;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation CALCR;RAMP3;OPRD1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1;CALCR GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;RAMP1;CALCR;RAMP3;RAMP2;OPRK1 GO:0032355| response to estradiol stimulus ESR1;RAMP2 GO:0051384| response to glucocorticoid stimulus UGT1A1;CALCR GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;CALCR GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;RAMP3 11014:[DB01183 DB02721] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02721|4-Iodopyrazole ADH1C;ADH1B;ADH1A common genes common pathways GO:0055114| oxidation-reduction process ADH1A;ADH1B;CYP2C8;CYP3A4;ADH1C GO:0017144| drug metabolic process CYP3A4;UGT1A1;ADH1A;CYP2C8 11015:[DB01183 DB01269] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01269|Panitumumab EGFR common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;CREB1;EGFR GO:0032355| response to estradiol stimulus EGFR;ESR1 GO:0050729| positive regulation of inflammatory response EGFR;TLR4 GO:0006468| protein phosphorylation EGFR;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TLR4;OPRM1;ESR1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;EGFR GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1;EGFR GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;EGFR;TLR4 GO:0048146| positive regulation of fibroblast proliferation EGFR;ESR1 GO:0007623| circadian rhythm EGFR;CREB1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;EGFR GO:0042060| wound healing OPRM1;EGFR GO:0001889| liver development UGT1A1;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;EGFR;TLR4;CREB1 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CREB1;ESR1 11016:[DB01183 DB09126] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;LHCGR;CREB1;TLR4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;LHCGR;OPRK1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger LHCGR;OPRM1;OPRD1 GO:0008584| male gonad development LHCGR;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;LHCGR;ESR1;OPRK1 11017:[DB01183 DB05369] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05369|HZT-501 HRH2 common genes common pathways GO:0006955| immune response OPRD1;HRH2;OPRK1;TLR4 GO:0008542| visual learning CREB1;HRH2 GO:0007186| G-protein coupled receptor signaling pathway HRH2;OPRM1;OPRD1;OPRK1 GO:0007613| memory HRH2;CREB1 GO:0007165| signal transduction OPRK1;CREB1;TLR4;OPRM1;OPRD1;ESR1;HRH2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HRH2;OPRM1;OPRD1 11018:[DB01183 DB01348] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1;SLCO1A2;SLC15A2 GO:0006811| ion transport SLC15A1;SLC15A2;SLCO1A2 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0007586| digestion UGT1A1;SLC15A1 11019:[DB01183 DB09186] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09186|Nisoxetine SLC6A4 common genes common pathways GO:0032355| response to estradiol stimulus SLC6A4;ESR1 GO:0007613| memory SLC6A4;CREB1 GO:0009636| response to toxin CES1;SLC6A4 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC6A4 GO:0010628| positive regulation of gene expression SLC6A4;TLR4 GO:0001666| response to hypoxia SLC6A4;CREB1 GO:0010033| response to organic substance SLC6A4;CREB1;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0007623| circadian rhythm CREB1;SLC6A4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;SLC6A4 11020:[DB01183 DB04703] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04703|Hesperidin AURKB common genes common pathways GO:0007568| aging AURKB;CREB1 GO:0006468| protein phosphorylation CREB1;AURKB GO:0000122| negative regulation of transcription from RNA polymerase II promoter AURKB;ESR1 11021:[DB01183 DB06825] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06825|Triptorelin GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;GNRHR;OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;GNRHR;OPRK1;CREB1;TLR4 11022:[DB01183 DB07216] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07216|(11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;FNTA 11023:[DB01183 DB01941] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;RXRB;ESR1 GO:0043401| steroid hormone mediated signaling pathway RXRB;ESR1 GO:0006351| transcription, DNA-dependent ESR1;RXRB;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRB;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;RXRB 11024:[DB01183 DB14575] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes CYP3A4;UGT1A1 common pathways GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;CYP2C8 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0006789| bilirubin conjugation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0042594| response to starvation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0006629| lipid metabolic process CYP3A4 GO:0007586| digestion UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0008152| metabolic process UGT1A1;CES1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CES1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8 GO:0001889| liver development UGT1A1 GO:0019233| sensory perception of pain P2RX4;OPRD1;OPRM1;OPRK1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0097190| apoptotic signaling pathway P2RX4;TLR4 GO:1904224| UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential P2RX4;OPRM1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0051552| flavone metabolic process UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1 GO:0010033| response to organic substance UGT1A1;CREB1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007584| response to nutrient UGT1A1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0002933| CYP2C8;CYP3A4 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0006811| ion transport SLCO1A2;P2RX4 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;P2RX4;ESR1;OPRD1;OPRM1 GO:0097267| CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8;CYP2C19 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;P2RX4;OPRM1;TLR4 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0070588| calcium ion transmembrane transport OPRM1;P2RX4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP3A4 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 11025:[DB01183 DB07514] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07514|3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0006468| protein phosphorylation CREB1;KDR GO:0030154| cell differentiation KDR;CREB1 GO:0010629| negative regulation of gene expression KDR;CREB1;ESR1;OPRD1 GO:0043491| protein kinase B signaling cascade KDR;CREB1 GO:0016032| viral reproduction KDR;CREB1 GO:0043066| negative regulation of apoptotic process ALB;KDR 11026:[DB01183 DB09270] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes ABCB1 common pathways GO:0007613| memory VLDLR;CREB1 GO:0006810| transport ABCB1 GO:0007568| aging HMGCR;CREB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C8;LDLR;UGT1A1;CYP3A4;VLDLR;HMGCR GO:0050729| positive regulation of inflammatory response LDLR;TLR4 GO:0045332| phospholipid translocation ABCB1 GO:0007165| signal transduction ESR1;VLDLR;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0006898| receptor-mediated endocytosis ALB;LDLR;VLDLR GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;OPRM1;HMGCR GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0007411| axon guidance VLDLR;CREB1 GO:0007584| response to nutrient HMGCR;UGT1A1 GO:0010628| positive regulation of gene expression TLR4;LDLR GO:0045471| response to ethanol UGT1A1;OPRK1;HMGCR;OPRM1 GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR;TLR4 GO:0006695| cholesterol biosynthetic process CES1;HMGCR GO:1901529| ABCB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VLDLR GO:0006629| lipid metabolic process LDLR;HMGCR;CYP3A4;VLDLR GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0071398| cellular response to fatty acid CREB1;LDLR GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;SDHA;HMGCR;NDUFV3;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;LDLR;CREB1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:0008542| visual learning HMGCR;CREB1 GO:0016032| viral reproduction CREB1;LDLR 11027:[DB01183 DB13149] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13149|Protein S human F5;F10;PROC common genes common pathways GO:0001889| liver development PROC;UGT1A1 GO:0002576| platelet degranulation F5;ALB GO:0043066| negative regulation of apoptotic process ALB;PROC GO:0043687| post-translational protein modification PROC;ALB;F5 GO:0044267| cellular protein metabolic process PROC;F5;ALB 11028:[DB01183 DB12406] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCB1 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP1A2;CYP3A4;CES1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 11029:[DB01183 DB07393] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways GO:0098869| ALB;GSR GO:0055114| oxidation-reduction process CYP3A4;GSR;CYP2C8 11030:[DB01183 DB01839] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01839|Propylene glycol F13A1 common genes common pathways GO:0002576| platelet degranulation F13A1;ALB 11031:[DB01183 DB05675] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05675|EP-2104R FGA common genes common pathways GO:0044267| cellular protein metabolic process FGA;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade FGA;TLR4;OPRM1 GO:0002376| immune system process TLR4;FGA GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;FGA;OPRK1 GO:0002224| toll-like receptor signaling pathway TLR4;FGA GO:0043687| post-translational protein modification FGA;ALB GO:0002576| platelet degranulation ALB;FGA GO:0045087| innate immune response TLR4;FGA 11032:[DB01183 DB02262] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0007595| lactation CREB1;DHODH GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0042493| response to drug DHODH;ABCB1;CREB1;UGT1A1 GO:0042594| response to starvation UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process DHODH;CREB1 GO:0014070| response to organic cyclic compound UGT1A1;DHODH 11033:[DB01183 DB03035] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03035|1,8-Di-Hydroxy-4-Nitro-Anthraquinone CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;CSNK2A1 GO:0007165| signal transduction OPRD1;CSNK2A1;OPRM1;ESR1;OPRK1;TLR4;CREB1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0048511| rhythmic process CREB1;CSNK2A1 11034:[DB01183 DB03222] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03222|dATP POLB;recA;recA common genes common pathways GO:0007568| aging POLB;CREB1 GO:0016579| protein deubiquitination POLB;ESR1 GO:0045471| response to ethanol OPRK1;UGT1A1;POLB;OPRM1 GO:0006954| inflammatory response POLB;TLR4 11035:[DB01183 DB04776] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways 11036:[DB01183 DB07379] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways GO:0030154| cell differentiation CDK6;CREB1 GO:0006468| protein phosphorylation CREB1;CDK6 GO:0014002| astrocyte development CDK6;TLR4 GO:0007165| signal transduction CDK6;CREB1;TLR4;OPRK1;OPRM1;OPRD1;ESR1 GO:0008285| negative regulation of cell proliferation CDK6;OPRM1 GO:0048146| positive regulation of fibroblast proliferation CDK6;ESR1 11037:[DB01183 DB08601] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08601|tributylstannanyl NCOA2;RXRA common genes common pathways GO:0048511| rhythmic process NCOA2;CREB1 GO:0015721| bile acid and bile salt transport SLCO1A2;NCOA2;RXRA;ALB GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0006355| regulation of transcription, DNA-dependent RXRA;CREB1;NCOA2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis RXRA;ESR1 GO:0016032| viral reproduction CREB1;RXRA GO:0006351| transcription, DNA-dependent CREB1;RXRA;NCOA2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;ESR1 GO:0007623| circadian rhythm CREB1;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;CREB1;TLR4;RXRA;ESR1 11038:[DB01183 DB07645] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways GO:0098869| HBA1;HBB;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4;HBB GO:0006898| receptor-mediated endocytosis ALB;HBB;HBA1 11039:[DB01183 DB04660] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04660|Choline alfoscerate GM2A common genes common pathways GO:0006629| lipid metabolic process GM2A;CYP3A4 11040:[DB01183 DB00073] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00073|Rituximab MS4A1 common genes common pathways 11041:[DB01183 DB06494] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06494|Sufugolix GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;GNRHR GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;GNRHR;TLR4;CREB1 11042:[DB01183 DB07108] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways GO:0042981| regulation of apoptotic process ESR1;BCL2L1;CREB1 GO:0009314| response to radiation OPRK1;BCL2L1;OPRM1 GO:0043065| positive regulation of apoptotic process BCL2L1;CREB1 GO:0043066| negative regulation of apoptotic process BCL2L1;ALB GO:0008584| male gonad development ESR1;BCL2L1 GO:0051881| regulation of mitochondrial membrane potential BCL2L1;OPRD1 11043:[DB01183 DB08642] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways GO:0051000| positive regulation of nitric-oxide synthase activity DHFR;ESR1 GO:0055114| oxidation-reduction process DHFR;CYP2C8;CYP3A4 11044:[DB01183 DB09409] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways GO:0006810| transport GRIN2C;ABCB1;GRIN2B;GRIN2A GO:0007613| memory GRIN2A;GRIN1;CREB1 GO:1900273| CREB1;GRIN2A GO:0070588| calcium ion transmembrane transport OPRM1;GRIN3B;GRIN3A GO:0008344| adult locomotory behavior OPRD1;GRIN1;GRIN2D GO:0006811| ion transport SLCO1A2;GRIN1;GRIN2D;GRIN2B;GRIN2A;GRIN2C;GRIN3A;GRIN3B GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;GRIN2D;GRIN2A;OPRK1 GO:1904646| GRIN1;GRIN2A;TLR4 GO:1903428| GRIN1;TLR4 GO:0019233| sensory perception of pain OPRM1;GRIN1;OPRD1;GRIN2A;OPRK1 GO:0045471| response to ethanol OPRK1;UGT1A1;GRIN3A;GRIN2A;GRIN1;OPRM1;GRIN2B GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN3B;GRIN3A;GRIN2C;GRIN2A;GRIN2B;OPRM1;GRIN2D;GRIN1 GO:0043065| positive regulation of apoptotic process CREB1;GRIN1;GRIN2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;ESR1;TLR4;CREB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;GRIN2A GO:0007268| synaptic transmission GRIN2B;OPRM1;OPRD1;GRIN2A;OPRK1 GO:0043278| response to morphine OPRK1;OPRM1;GRIN1 GO:0008542| visual learning GRIN1;GRIN2A;CREB1 GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 11045:[DB01183 DB00048] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways GO:0042060| wound healing OPRM1;COL3A1;COL1A1 GO:0071560| cellular response to transforming growth factor beta stimulus COL1A1;CREB1 GO:0009314| response to radiation OPRM1;COL3A1;OPRK1 GO:0071260| cellular response to mechanical stimulus COL1A1;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;COL1A1;ESR1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;COL1A1 GO:0032355| response to estradiol stimulus COL1A1;ESR1 GO:0007568| aging CREB1;COL3A1 GO:0048545| response to steroid hormone stimulus UGT1A1;COL1A1 GO:0007179| transforming growth factor beta receptor signaling pathway COL1A2;CREB1;COL3A1 GO:0007584| response to nutrient UGT1A1;COL1A1 11046:[DB01183 DB00102] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00102|Becaplermin PDGFRB;PDGFRA;A2M common genes common pathways GO:0043066| negative regulation of apoptotic process PDGFRB;ALB GO:0002576| platelet degranulation A2M;ALB GO:0043065| positive regulation of apoptotic process PDGFRB;CREB1 GO:0042060| wound healing OPRM1;PDGFRB;PDGFRA GO:0016032| viral reproduction PDGFRA;CREB1 GO:0048863| stem cell differentiation ESR1;A2M GO:0010863| positive regulation of phospholipase C activity ESR1;PDGFRB;PDGFRA GO:0007165| signal transduction OPRD1;OPRM1;ESR1;TLR4;CREB1;PDGFRB;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PDGFRB GO:0036120| PDGFRB;CREB1 GO:0032355| response to estradiol stimulus PDGFRB;ESR1 GO:0007568| aging PDGFRB;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;PDGFRA GO:0006468| protein phosphorylation PDGFRA;CREB1;PDGFRB GO:0048146| positive regulation of fibroblast proliferation PDGFRB;PDGFRA;ESR1 GO:0008584| male gonad development ESR1;PDGFRB GO:0043627| response to estrogen stimulus OPRK1;PDGFRB;ESR1 GO:0009636| response to toxin CES1;PDGFRB GO:0014070| response to organic cyclic compound UGT1A1;PDGFRB GO:0070374| positive regulation of ERK1 and ERK2 cascade PDGFRB;TLR4;PDGFRA;OPRM1 11047:[DB01183 DB00941] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00941|Hexafluronium BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0042493| response to drug UGT1A1;BCHE;CREB1;ABCB1 11048:[DB01183 DB04581] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04581|1-benzylimidazole QPCT common genes common pathways 11049:[DB01183 DB02046] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02046|N-[(Furan-2-Yl)Carbonyl]-(S)-Leucyl-(R)-[1-Amino-2(1h-Indol-3-Yl)Ethyl]-Phosphonic Acid ADAM28 common genes common pathways 11050:[DB01183 DB06264] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06264|Tolperisone CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;UGT1A1 GO:0097267| CYP2C8;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CES1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;UGT1A1;CREB1;ABCB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 11051:[DB01183 DB00068] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00068|Interferon beta-1b IFNAR1;IFNAR2 common genes common pathways GO:0051607| defense response to virus OPRK1;IFNAR2 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;IFNAR1 11052:[DB01183 DB08378] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08378|4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID MYL6B;MYL12A;MYH7 common genes common pathways 11053:[DB01183 DB01699] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0001666| response to hypoxia CREB1;ABAT GO:0042220| response to cocaine OPRK1;ABAT;OPRM1 GO:0007568| aging CREB1;ABAT GO:0035094| response to nicotine ABAT;CREB1 GO:0042493| response to drug ABCB1;ABAT;CREB1;UGT1A1 GO:0048148| behavioral response to cocaine ABAT;OPRK1 GO:0007626| locomotory behavior OPRK1;ABAT;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;ABAT 11054:[DB01183 DB06937] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways GO:0007165| signal transduction CREB1;TLR4;ESR2;OPRK1;ESR1;OPRM1;OPRD1 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;ESR2 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR2;ESR1 11055:[DB01183 DB07800] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07800|N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE F10 common genes common pathways 11056:[DB01183 DB08169] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;DHODH GO:0042594| response to starvation UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process CREB1;DHODH GO:0007595| lactation DHODH;CREB1 GO:0055114| oxidation-reduction process CYP2C8;DHODH;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;DHODH 11057:[DB01183 DB06263] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0042752| regulation of circadian rhythm CREB1;TOP2A GO:0055114| oxidation-reduction process POR;CYP2C8;CBR1;CYP3A4 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;POR GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TOP2A;TLR4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;POR GO:0043066| negative regulation of apoptotic process ALB;POR GO:0048511| rhythmic process TOP2A;CREB1 GO:0007584| response to nutrient POR;UGT1A1 GO:0006855| drug transmembrane transport ABCB1;ABCB5 GO:0055085| transmembrane transport SLCO1A2;ABCB5;ABCB1 GO:0030855| epithelial cell differentiation CES1;CBR1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CBR1;CYP3A4 GO:0030154| cell differentiation CREB1;ABCB5 GO:0042908| xenobiotic transport ABCB1;ABCB5 11058:[DB01183 DB08709] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08709|2,3-diphenyl-1H-indole-7-carboxylic acid PIM1 common genes common pathways GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1;PIM1 GO:0006468| protein phosphorylation CREB1;PIM1 GO:0043066| negative regulation of apoptotic process ALB;PIM1 11059:[DB01183 DB03725] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PCK1 GO:0032496| response to lipopolysaccharide OPRM1;PCK1;TLR4;UGT1A1 GO:0014823| response to activity CREB1;PCK1 GO:0032868| response to insulin stimulus OPRK1;PCK1 GO:0071456| cellular response to hypoxia OPRD1;PCK1 GO:0007568| aging PCK1;CREB1 11060:[DB01183 DB06938] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06938|4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR GO:0043491| protein kinase B signaling cascade CREB1;KDR GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;KDR GO:0016032| viral reproduction KDR;CREB1 GO:0030154| cell differentiation CREB1;KDR GO:0006468| protein phosphorylation CREB1;KDR GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process KDR;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;KDR 11061:[DB01183 DB05710] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA3;OPRM1 GO:0007626| locomotory behavior OPRK1;CHRNA3;OPRM1 GO:0007165| signal transduction CHRNA3;OPRK1;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0006811| ion transport SLCO1A2;CHRNA3 11062:[DB01183 DB02165] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways GO:0008152| metabolic process UGT1A1;GSTM1;CES1 11063:[DB01183 DB02824] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways GO:1990830| SHMT1;CREB1 11064:[DB01183 DB06757] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0045087| innate immune response ARG1;TLR4 GO:0002576| platelet degranulation ALB;TF GO:0071222| cellular response to lipopolysaccharide ARG1;TLR4;OPRK1 GO:0008152| metabolic process CES1;UGT1A1;ACO1 GO:0071560| cellular response to transforming growth factor beta stimulus ARG1;CREB1 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TAB1;TLR4 GO:0001889| liver development UGT1A1;ARG1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;ARG1 GO:0002756| MyD88-independent toll-like receptor signaling pathway TAB1;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TAB1 GO:0055114| oxidation-reduction process IDH3A;CYP2C8;IDH3G;CYP3A4 GO:0043687| post-translational protein modification ALB;TF GO:0042493| response to drug ARG1;UGT1A1;CREB1;ABCB1 GO:0048545| response to steroid hormone stimulus ARG1;UGT1A1 GO:0002376| immune system process TLR4;ARG1 GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR4;TAB1 GO:0007568| aging CREB1;ARG1 GO:0016579| protein deubiquitination TAB1;ESR1 GO:0000187| activation of MAPK activity TLR4;TAB1 GO:0001895| retina homeostasis ALB;TF GO:0044267| cellular protein metabolic process TF;ALB GO:0007179| transforming growth factor beta receptor signaling pathway TAB1;CREB1 GO:0006811| ion transport SLCO1A2;TF 11065:[DB01183 DB00753] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes ALB common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0071294| cellular response to zinc ion GLRA1;CREB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0019233| sensory perception of pain CHRNA4;OPRD1;OPRM1;OPRK1;CHRNB2 GO:0045471| response to ethanol CHRNB2;UGT1A1;OPRK1;OPRM1;CYP2E1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;TLR4 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIA1;GLRA1;CHRNB2;CHRNA4;OPRM1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C8;CES1;CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation CALM1;ALB GO:0007626| locomotory behavior CHRNB2;OPRK1;OPRM1;CHRNA4 GO:0007218| neuropeptide signaling pathway GLRA1;OPRK1;OPRM1;OPRD1 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0033603| positive regulation of dopamine secretion CHRNB2;OPRK1 GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C8;CYP3A4 GO:0042493| response to drug CYP2E1;GABRG3;UGT1A1;MT-ND1;CREB1;ABCB1 GO:0007268| synaptic transmission GRIA1;KCNA1;OPRK1;GABRA5;GABRG1;GLRA1;GABRB2;GABRD;CHRNA4;GABRG2;OPRD1;OPRM1 GO:1901215| CREB1;GABRB2;GABRB3 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2B6;MT-ND1;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0008542| visual learning CHRNB2;CREB1 GO:0035094| response to nicotine CHRNB2;CREB1;CHRNA4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2B6;UGT1A1;CYP2C8;CYP2E1;CYP3A4 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway CALM1;OPRD1;OPRM1;OPRK1 GO:0006810| transport GABRB3;GABRB1;GABRG2;GABRA4;GABRA6;GABRA1;ABCB1;GABRA3;GABRA5;GABRB2;GABRD GO:0043069| negative regulation of programmed cell death ALB GO:0007613| memory CHRNB2;CREB1 GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0070588| calcium ion transmembrane transport OPRM1;ATP2C1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2B6;UGT1A1;CYP2C8 GO:0007165| signal transduction GRIA1;OPRK1;GABRA5;CHRNB2;GABRP;TLR4;CREB1;GABRD;ATP2C1;CHRNA4;GABRB3;GABRB1;OPRD1;GABRQ;GABRE;OPRM1;GABRA6;ESR1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0014070| response to organic cyclic compound MT-ND1;UGT1A1 GO:0009636| response to toxin GABRB1;CES1 GO:0006811| ion transport GABRA4;GABRA6;GABRA1;GABRE;SLCO1A2;GABRG2;GABRB1;GABRQ;GABRB3;GABRG3;CHRNA4;ATP2C1;GABRB2;GABRD;GABRP;GLRA1;CHRNB2;GABRG1;GABRA5;GABRA3;GABRA2;GRIA1;KCNA1 GO:0001895| retina homeostasis ALB GO:0042220| response to cocaine OPRM1;OPRK1;CHRNB2 GO:0044267| cellular protein metabolic process ALB GO:0055085| transmembrane transport KCNA1;ABCB1;SLCO1A2;CALM1 GO:0001666| response to hypoxia CHRNA4;CREB1;CHRNB2 GO:0030890| positive regulation of B cell proliferation CHRNB2;TLR4 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB 11066:[DB01183 DB00121] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways GO:0097267| CYP1B1;CYP2C8 GO:0006810| transport ABCB1;SLC5A6 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP1B1 GO:0008285| negative regulation of cell proliferation OPRM1;CYP1B1 GO:0055085| transmembrane transport SLC5A6;ABCB1;SLCO1A2 GO:0006811| ion transport SLCO1A2;SLC5A6 GO:0009636| response to toxin CES1;CYP1B1 GO:0014070| response to organic cyclic compound ACACB;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;ACACA;ACACB;PC GO:0043065| positive regulation of apoptotic process CREB1;CYP1B1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP1B1 GO:0008152| metabolic process CES1;ACACA;HLCS;PC;ACACB;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0055114| oxidation-reduction process CYP1B1;CYP2C8;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;OPRD1;PC;ACACB;CREB1 GO:0042493| response to drug ACACB;ABCB1;UGT1A1;CREB1 GO:0043086| negative regulation of catalytic activity UGT1A1;ACACB 11067:[DB01183 DB05432] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05432|DAS-431 IV CALY common genes common pathways 11068:[DB01183 DB05389] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways GO:0006898| receptor-mediated endocytosis CD163;ALB GO:0006953| acute-phase response UGT1A1;CD163 GO:0006954| inflammatory response CD163;TLR4 11069:[DB01183 DB04901] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04901|Galiximab CD80 common genes common pathways GO:0016032| viral reproduction CD80;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CREB1 11070:[DB01183 DB06393] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06393|Xaliproden HTR1A common genes common pathways GO:0007610| behavior OPRK1;HTR1A GO:0007165| signal transduction OPRM1;OPRD1;ESR1;HTR1A;CREB1;TLR4;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;OPRD1;OPRM1;OPRK1 11071:[DB01183 DB04173] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04173|Fructose FHIT common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;FHIT GO:0006351| transcription, DNA-dependent FHIT;ESR1;CREB1 11072:[DB01183 DB12582] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006351| transcription, DNA-dependent ESR1;NR1I2;CREB1 GO:0043401| steroid hormone mediated signaling pathway NR1I2;ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;NR1I2;ESR1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2C9;NR1I2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;NR1I2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NR1I2;CYP2C9 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;ESR1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;NR1I2;UGT1A1;CYP3A4 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;NR1I2;TLR4 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0010628| positive regulation of gene expression TLR4;NR1I2 11073:[DB01183 DB04213] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways GO:0009636| response to toxin EPHX2;CES1 GO:0010628| positive regulation of gene expression TLR4;EPHX2 GO:0017144| drug metabolic process EPHX2;CYP3A4;CYP2C8;UGT1A1 GO:0006954| inflammatory response EPHX2;TLR4 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0008152| metabolic process CES1;EPHX2;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CES1;CYP3A4;EPHX2 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2C8 11074:[DB01183 DB03722] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03722|3,4-Dihydro-5-Methyl-Isoquinolinone PARP1 common genes common pathways GO:1904646| TLR4;PARP1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;PARP1 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0006351| transcription, DNA-dependent CREB1;PARP1;ESR1 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PARP1 11075:[DB01183 DB07232] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07232|Veliparib PARP1;PARP2 common genes common pathways GO:0006366| transcription from RNA polymerase II promoter PARP1;ESR1;CREB1 GO:0007179| transforming growth factor beta receptor signaling pathway CREB1;PARP1 GO:1904646| PARP1;TLR4 GO:0006355| regulation of transcription, DNA-dependent PARP1;ESR1;CREB1 GO:0071294| cellular response to zinc ion CREB1;PARP1 GO:0006351| transcription, DNA-dependent CREB1;PARP1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PARP1;CREB1;TLR4 GO:0071560| cellular response to transforming growth factor beta stimulus PARP1;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PARP1 11076:[DB01183 DB05855] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05855|Rivanicline CHRNB2;CXCL8 common genes common pathways GO:0045471| response to ethanol OPRM1;CHRNB2;UGT1A1;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNB2;OPRM1 GO:0019233| sensory perception of pain CHRNB2;OPRK1;OPRD1;OPRM1 GO:0071222| cellular response to lipopolysaccharide TLR4;CXCL8;OPRK1 GO:0007626| locomotory behavior OPRM1;OPRK1;CHRNB2 GO:0033603| positive regulation of dopamine secretion OPRK1;CHRNB2 GO:0006954| inflammatory response CXCL8;TLR4 GO:0006955| immune response OPRD1;OPRK1;CXCL8;TLR4 GO:0008542| visual learning CREB1;CHRNB2 GO:0035094| response to nicotine CREB1;CHRNB2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CXCL8;OPRD1;OPRM1 GO:0007613| memory CHRNB2;CREB1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CXCL8;CREB1;TLR4;CHRNB2 GO:0006811| ion transport CHRNB2;SLCO1A2 GO:0042220| response to cocaine OPRM1;OPRK1;CHRNB2 GO:0001666| response to hypoxia CREB1;CHRNB2 GO:0030890| positive regulation of B cell proliferation CHRNB2;TLR4 GO:0008285| negative regulation of cell proliferation CXCL8;OPRM1 11077:[DB01183 DB03893] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GAPDH;CYP2C8 GO:0050821| protein stabilization GAPDH;CREB1 11078:[DB01183 DB08262] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;HBB;ESR1;OPRM1 GO:0098869| ALB;HBB;HBA1 GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 11079:[DB01183 DB08745] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08745|4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE F10 common genes common pathways 11080:[DB01183 DB05122] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways 11081:[DB01183 DB04065] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ADH1A;CYP2C8 GO:0017144| drug metabolic process CYP3A4;ADH1A;UGT1A1;CYP2C8 11082:[DB01183 DB04720] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04720|S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CSNK2A1;CREB1 GO:0006468| protein phosphorylation CREB1;CSNK2A1 GO:0007165| signal transduction ESR1;CSNK2A1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0048511| rhythmic process CSNK2A1;CREB1 11083:[DB01183 DB07965] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07965|6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)-ethyl]-9H-purine-2-carbonitrile CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 11084:[DB01183 DB08689] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways GO:0055114| oxidation-reduction process SDHA;SDHD;CYP3A4;SDHB;SDHC;CYP2C8 11085:[DB01183 DB05079] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05079|HY10275 HRH1;HTR2A common genes common pathways GO:0007613| memory HRH1;HTR2A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1 GO:0007568| aging HTR2A;CREB1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;HRH1;OPRD1;HTR2A GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;HTR2A;OPRM1;OPRD1;HRH1 GO:0007610| behavior HTR2A;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HTR2A;TLR4 GO:0045600| positive regulation of fat cell differentiation HTR2A;CREB1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;HRH1;ESR1;HTR2A GO:0019233| sensory perception of pain HTR2A;OPRD1;OPRM1;OPRK1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0042493| response to drug HTR2A;ABCB1;UGT1A1;CREB1 GO:0007268| synaptic transmission HTR2A;OPRD1;OPRM1;OPRK1 GO:0008542| visual learning HRH1;CREB1 GO:0006954| inflammatory response TLR4;HRH1 GO:0016032| viral reproduction CREB1;HTR2A 11086:[DB01183 DB05403] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05403|CEP-1347 MAPK12 common genes common pathways GO:0006468| protein phosphorylation MAPK12;CREB1 GO:0007165| signal transduction OPRK1;MAPK12;TLR4;CREB1;OPRD1;OPRM1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;MAPK12;ESR1 GO:0006351| transcription, DNA-dependent ESR1;MAPK12;CREB1 11087:[DB01183 DB05961] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways GO:0002376| immune system process TLR4;SERPING1 GO:0007568| aging SERPING1;CREB1 GO:0044267| cellular protein metabolic process SERPINA1;ALB GO:0045087| innate immune response TLR4;SERPING1 GO:0002576| platelet degranulation SERPINA1;SERPING1;ALB GO:0006953| acute-phase response UGT1A1;SERPINA1 GO:0043687| post-translational protein modification ALB;SERPINA1 11088:[DB01183 DB04982] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways GO:0007165| signal transduction ESR1;OPRD1;OPRM1;GRIA2;TLR4;CREB1;OPRK1;GRIA1 GO:0006810| transport ABCB1;GRIA4;GRIA3 GO:0006811| ion transport GRIA3;SLCO1A2;GRIA2;GRIA4;GRIA1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIA4;GRIA1;OPRM1;GRIA3;GRIA2 GO:0007268| synaptic transmission OPRM1;OPRD1;GRIA2;OPRK1;GRIA1 11089:[DB01183 DB11386] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11386|Chlorobutanol KCNH2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;KCNH2 GO:0006811| ion transport KCNH2;SLCO1A2 GO:1901381| KCNH2;OPRK1 11090:[DB01183 DB06021] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06021|AV-412 EGFR;ERBB2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;EGFR GO:0006355| regulation of transcription, DNA-dependent ERBB2;ESR1;CREB1 GO:0042060| wound healing ERBB2;OPRM1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;ESR1;EGFR GO:0007623| circadian rhythm CREB1;EGFR GO:0006351| transcription, DNA-dependent CREB1;ESR1;ERBB2 GO:0001889| liver development EGFR;UGT1A1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;EGFR;ESR1 GO:0071260| cellular response to mechanical stimulus EGFR;TLR4 GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;EGFR GO:0048146| positive regulation of fibroblast proliferation ESR1;EGFR GO:0010628| positive regulation of gene expression TLR4;ERBB2 GO:0050729| positive regulation of inflammatory response TLR4;EGFR GO:0071363| cellular response to growth factor stimulus CREB1;EGFR;OPRD1;ERBB2 GO:0032355| response to estradiol stimulus ESR1;EGFR GO:0006468| protein phosphorylation CREB1;EGFR;ERBB2 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;EGFR;TLR4 GO:0007165| signal transduction ERBB2;ESR1;OPRD1;OPRM1;OPRK1;EGFR;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1 11091:[DB01183 DB04869] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04869|Olcegepant CALCA;CALCRL common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CALCRL GO:0045671| negative regulation of osteoclast differentiation TLR4;CALCA GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CALCRL;CREB1;TLR4;OPRK1 GO:0032757| positive regulation of interleukin-8 production CALCA;TLR4 GO:0006468| protein phosphorylation CREB1;CALCA GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;CALCA;CALCRL GO:0045087| innate immune response CALCA;TLR4 GO:0050829| defense response to Gram-negative bacterium CALCA;TLR4 11092:[DB01183 DB13951] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes ABCB1;ESR1 common pathways GO:0008210| estrogen metabolic process HSD17B1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR;NR3C2 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process HSD17B1;CYP11A1;CYP3A4;CYP2C8;CYP17A1;CYP19A1 GO:2001225| regulation of chloride transport ABCB1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;NR3C2;ESR1;AR GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0006629| lipid metabolic process CYP3A4;CYP11A1;HSD17B1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;TLR4;CREB1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0060065| uterus development ESR1;CYP19A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;ESR1;OPRK1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;NR3C2 GO:0006351| transcription, DNA-dependent AR;ESR1;NR3C2;CREB1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:1901529| ABCB1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1;AR GO:0008584| male gonad development ESR1;AR GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0030879| mammary gland development CREB1;CYP19A1 GO:0007165| signal transduction AR;OPRD1;OPRM1;ESR1;OPRK1;NR3C2;TLR4;CREB1 GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1;AR GO:0032355| response to estradiol stimulus ESR1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP11A1;UGT1A1;CYP17A1;CYP2C8 11093:[DB01183 DB09202] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0007165| signal transduction CREB1;TLR4;ADRA1D;ADRA2A;OPRK1;ADRA1A;ADRA2C;ESR1;ADRA2B;OPRM1;OPRD1;ADRA1B GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1 GO:0007568| aging ADRA1A;CREB1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;ADRA1D;ADRA1B;ESR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRA2A;ADRA1A;ADRA1D;ADRA1B;ADRA2B;ADRA2C;OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation ADRA1A;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0000187| activation of MAPK activity ADRA2B;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;ADRA1A;OPRM1 GO:0051930| regulation of sensory perception of pain OPRK1;ADRA2C;OPRD1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRK1;ADRA1D;ADRA1B;OPRM1;OPRD1;ESR1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ADRA1A 11094:[DB01183 DB09161] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug UGT1A1;ABCC1;CREB1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;ABCC1 11095:[DB01183 DB00141] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways GO:0042060| wound healing B4GALT1;OPRM1 GO:0043065| positive regulation of apoptotic process B4GALT1;CREB1 GO:0007626| locomotory behavior OPRM1;B4GALT2;OPRK1 GO:0008152| metabolic process CES1;UGT1A1;NAGLU GO:0043086| negative regulation of catalytic activity UGT1A1;RENBP GO:0008542| visual learning B4GALT2;CREB1 GO:0007613| memory B4GALT2;CREB1 GO:0002064| epithelial cell development B4GALT1;ESR1 GO:0030879| mammary gland development CREB1;B4GALT1 GO:0008285| negative regulation of cell proliferation B4GALT1;OPRM1 11096:[DB01183 DB03904] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways GO:0030154| cell differentiation CREB1;CTNNB1 GO:0007568| aging ARG1;CREB1 GO:0032355| response to estradiol stimulus CTNNB1;ESR1 GO:0071363| cellular response to growth factor stimulus OPRD1;CTNNB1;CREB1 GO:0048545| response to steroid hormone stimulus ARG1;CA2;UGT1A1 GO:0048145| regulation of fibroblast proliferation CREB1;CTNNB1 GO:0002376| immune system process ARG1;TLR4 GO:0045671| negative regulation of osteoclast differentiation TLR4;CTNNB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1;CTNNB1 GO:0055085| transmembrane transport ABCB1;SLC14A1;SLC14A2;SLCO1A2 GO:0043627| response to estrogen stimulus ESR1;OPRK1;CA2 GO:0008285| negative regulation of cell proliferation OPRM1;CTNNB1 GO:0010033| response to organic substance CREB1;UGT1A1;CA2 GO:0010628| positive regulation of gene expression CTNNB1;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTNNB1;TLR4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;CTNNB1 GO:0001889| liver development UGT1A1;ARG1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;CTNNB1 GO:0032496| response to lipopolysaccharide OPRM1;ARG1;TLR4;UGT1A1 GO:0045087| innate immune response ARG1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CTNNB1;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1;CTNNB1 GO:0043065| positive regulation of apoptotic process CTNNB1;CREB1 GO:0045672| positive regulation of osteoclast differentiation CREB1;CA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CTNNB1;ESR1;TLR4;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ARG1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;ARG1 GO:1901215| CREB1;CTNNB1 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CTNNB1;ARG1 GO:0007268| synaptic transmission OPRM1;OPRD1;CTNNB1;OPRK1 GO:0010629| negative regulation of gene expression ESR1;CTNNB1;OPRD1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;CTNNB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CTNNB1;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;CTNNB1 11097:[DB01183 DB07177] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGR2;PTGR1 11098:[DB01183 DB03793] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0098869| ALB;PRDX5 GO:0006810| transport ABCB1;SLC15A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1A2;SLC22A8 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;SLCO2B1 GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLC15A1;SLC16A1;SLCO1A2;SLC22A8 GO:0006811| ion transport SLC22A8;SLCO1A2;SLC15A1;SLCO2B1 GO:0009636| response to toxin CES1;SLC22A8 GO:0006629| lipid metabolic process CYP3A4;SLC16A1 GO:0007586| digestion UGT1A1;SLC15A1 GO:0043066| negative regulation of apoptotic process PRDX5;ALB GO:0006954| inflammatory response TLR4;PRDX5 GO:0055114| oxidation-reduction process DAO;CYP2C8;CYP3A4;PRDX5 GO:0032094| response to food OPRM1;SLC16A1 11099:[DB01183 DB08232] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways GO:0014070| response to organic cyclic compound F7;UGT1A1 GO:0043627| response to estrogen stimulus ESR1;OPRK1;F7 GO:0001666| response to hypoxia F7;CREB1 GO:0032355| response to estradiol stimulus F7;ESR1 GO:0031100| organ regeneration F7;UGT1A1 GO:0007623| circadian rhythm F7;CREB1 11100:[DB01183 DB02731] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways GO:0014823| response to activity OXCT1;CREB1 GO:0007584| response to nutrient UGT1A1;OXCT1 GO:0045471| response to ethanol OPRM1;UGT1A1;OPRK1;OXCT1 GO:0008152| metabolic process UGT1A1;OXCT1;CES1 GO:0042594| response to starvation UGT1A1;OXCT1 GO:0042493| response to drug OXCT1;ABCB1;CREB1;UGT1A1 11101:[DB01183 DB07984] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CYP3A4;CES1 GO:0055114| oxidation-reduction process CYP2C8;PTGS1;CYP3A4 GO:0006954| inflammatory response TLR4;PTGS1 GO:0098869| ALB;PTGS1 11102:[DB01183 DB07983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;PTGS1 GO:0006954| inflammatory response TLR4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP2C8 11103:[DB01183 DB01616] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01616|Alverine HTR1A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;HTR1A;OPRM1;OPRD1 GO:0007165| signal transduction HTR1A;ESR1;OPRM1;OPRD1;CREB1;TLR4;OPRK1 GO:0007610| behavior OPRK1;HTR1A 11104:[DB01183 DB07769] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0010628| positive regulation of gene expression AR;TLR4 GO:0008584| male gonad development AR;ESR1 GO:0016579| protein deubiquitination ESR1;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1 GO:0006810| transport AR;ABCB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;AR;ESR1;OPRD1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;CREB1;TLR4 GO:0060749| mammary gland alveolus development ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR 11105:[DB01183 DB00881] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0009636| response to toxin CES1;SLC22A8 GO:0006811| ion transport SLC15A1;SLCO1A2;SLC22A8;SLC15A2 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO1A2;SLC22A8;SLC15A2 11106:[DB01183 DB07454] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;AR GO:0006810| transport ABCB1;AR GO:0008584| male gonad development AR;ESR1 GO:0010628| positive regulation of gene expression TLR4;AR GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0016579| protein deubiquitination ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060749| mammary gland alveolus development ESR1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0043401| steroid hormone mediated signaling pathway AR;ESR1 GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TLR4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1 11107:[DB01183 DB08489] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08489|N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YL)-SUCCINAMIDE MMP7 common genes common pathways GO:0071260| cellular response to mechanical stimulus TLR4;MMP7 GO:0007568| aging CREB1;MMP7 GO:0044849| OPRM1;MMP7;OPRK1 11108:[DB01183 DB09117] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09117|Paraldehyde ALDH2 common genes common pathways GO:0008152| metabolic process CES1;ALDH2;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;ALDH2;CYP2C8 11109:[DB01183 DB00170] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;UGT1A1 GO:0007623| circadian rhythm F7;CREB1 GO:0032496| response to lipopolysaccharide TLR4;CYP1A1;UGT1A1;OPRM1;CYP1A2 GO:0001889| liver development PROC;CYP1A1;UGT1A1 GO:0045471| response to ethanol OPRK1;NQO1;UGT1A1;CYP2E1;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0008152| metabolic process MTHFR;CES1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;NQO2;NQO1;CYP1A2;CES1;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP1A2;CYP1A1;CYP2C8 GO:0043066| negative regulation of apoptotic process PROC;NQO1;ALB GO:0002576| platelet degranulation PROS1;ALB GO:1900745| OPRK1;XDH GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 GO:0032094| response to food CYP1A1;OPRM1 GO:0042493| response to drug CYP1A1;CREB1;UGT1A1;ABCB1;CYP2E1;CYP1A2;MTHFR GO:0010629| negative regulation of gene expression ESR1;OPRD1;XDH;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2A6;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;AOX1;CYP1A1;NQO1;NQO2;VKORC1L1;CYP2A6;CYP3A4;CYP2E1;MTHFR;XDH;VKORC1;CYP1A2 GO:0043687| post-translational protein modification PROC;ALB GO:0006953| acute-phase response UGT1A1;F2 GO:0007595| lactation XDH;CREB1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2E1;CYP1A2;CYP1A1;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus F7;NQO1;ESR1;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;F2;OPRM1;OPRD1 GO:0007568| aging CREB1;CYP1A1;NQO1 GO:0031100| organ regeneration UGT1A1;F7 GO:0070989| oxidative demethylation CYP2C8;CYP1A2;CYP3A4 GO:0097267| CYP2C8;CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6;VKORC1;CYP1A2;CYP1A1;AOX1;UGT1A1;CYP2C8 GO:0002933| CYP3A4;CYP1A1;CYP2C8 GO:0014070| response to organic cyclic compound UGT1A1;NQO1;CYP1A1;F7;CYP1A2 GO:0009636| response to toxin CYP1A1;NQO1;CES1 GO:0044267| cellular protein metabolic process ALB;F2;PROC GO:0001666| response to hypoxia CREB1;CYP1A1;F7;MTHFR GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0010033| response to organic substance CYP1A1;CREB1;UGT1A1;CYP1A2 GO:0043627| response to estrogen stimulus F7;OPRK1;ESR1 GO:0007584| response to nutrient NQO1;UGT1A1 11110:[DB01183 DB08577] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways GO:0010863| positive regulation of phospholipase C activity ESR1;FGFR1 GO:0006468| protein phosphorylation CREB1;FGFR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;ESR1 GO:0006351| transcription, DNA-dependent ESR1;FGFR1;CREB1 GO:0006355| regulation of transcription, DNA-dependent FGFR1;ESR1;CREB1 GO:0010629| negative regulation of gene expression CREB1;FGFR1;ESR1;OPRD1 11111:[DB01183 DB07347] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07347|4-(2-Aminoethyl)Benzenesulfonyl Fluoride GAPDH;ATP6V1B2 common genes common pathways GO:0006811| ion transport ATP6V1B2;SLCO1A2 GO:0050821| protein stabilization CREB1;GAPDH GO:0055114| oxidation-reduction process GAPDH;CYP3A4;CYP2C8 11112:[DB01183 DB01339] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01339|Vecuronium CHRNA2;ABCB1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;CHRNA2;OPRD1;OPRM1;ESR1 GO:0006811| ion transport SLCO1A2;CHRNA2 GO:0006855| drug transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:1901529| ABCB1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA2;OPRM1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0035094| response to nicotine CHRNA2;CREB1 11113:[DB01183 DB03891] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03891|1,5-Bis(N-Benzyloxycarbonyl-L-Leucinyl)Carbohydrazide CTSK common genes common pathways GO:0002224| toll-like receptor signaling pathway TLR4;CTSK 11114:[DB01183 DB05214] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05214|KD7040 NOS2 common genes common pathways GO:0010629| negative regulation of gene expression ESR1;OPRD1;NOS2;CREB1 GO:0009617| response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process CYP2C8;NOS2;CYP3A4 GO:0042742| defense response to bacterium TLR4;NOS2 GO:0007623| circadian rhythm NOS2;CREB1 GO:0032496| response to lipopolysaccharide OPRM1;NOS2;TLR4;UGT1A1 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;NOS2;OPRK1 GO:0001666| response to hypoxia CREB1;NOS2 11115:[DB01183 DB03468] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03468|1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide PNMT common genes common pathways 11116:[DB01183 DB00587] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00587|Cinalukast CYSLTR1 common genes common pathways GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;CYSLTR1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CYSLTR1;OPRK1;OPRD1;OPRM1;ESR1 GO:0007165| signal transduction TLR4;CREB1;CYSLTR1;OPRK1;OPRD1;OPRM1;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration CYSLTR1;ESR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;CYSLTR1;OPRM1;OPRD1 11117:[DB01183 DB05939] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05939|MK-0354 GPER1 common genes common pathways GO:0010629| negative regulation of gene expression GPER1;ESR1;OPRD1;CREB1 GO:0030518| intracellular steroid hormone receptor signaling pathway GPER1;ESR1 GO:0006954| inflammatory response GPER1;TLR4 GO:0043401| steroid hormone mediated signaling pathway ESR1;GPER1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GPER1;CREB1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;GPER1 GO:0045087| innate immune response GPER1;TLR4 GO:0070373| negative regulation of ERK1 and ERK2 cascade GPER1;TLR4 GO:0050769| positive regulation of neurogenesis GPER1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPER1;OPRM1;TLR4 GO:0010628| positive regulation of gene expression TLR4;GPER1 GO:0008285| negative regulation of cell proliferation OPRM1;GPER1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;OPRD1;GPER1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;GPER1 GO:0030154| cell differentiation GPER1;CREB1 GO:0071392| cellular response to estradiol stimulus UGT1A1;GPER1;ESR1 GO:0002376| immune system process TLR4;GPER1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;GPER1 11118:[DB01183 DB00272] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00272|Betazole HRH2 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;OPRD1;HRH2 GO:0007165| signal transduction ESR1;HRH2;OPRM1;OPRD1;OPRK1;CREB1;TLR4 GO:0007613| memory CREB1;HRH2 GO:0007186| G-protein coupled receptor signaling pathway HRH2;OPRM1;OPRD1;OPRK1 GO:0008542| visual learning HRH2;CREB1 GO:0006955| immune response TLR4;OPRK1;HRH2;OPRD1 11119:[DB01183 DB00952] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0045471| response to ethanol HTR1B;OPRK1;UGT1A1;OPRM1 GO:0007268| synaptic transmission OPRK1;HTR1F;HTR1B;HTR1D;OPRD1;OPRM1 GO:0042493| response to drug ABCB1;HTR1B;CREB1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;MAOA GO:0007165| signal transduction HTR1B;HTR1F;OPRK1;TLR4;CREB1;OPRD1;HTR1D;OPRM1;HTR1A;ESR1 GO:0007610| behavior HTR1B;OPRK1;HTR1A GO:0007186| G-protein coupled receptor signaling pathway HTR1F;OPRK1;HTR1B;HTR1A;OPRM1;OPRD1;HTR1D GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway HTR1B;HTR1F;OPRK1;OPRD1;HTR1D;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR1F;HTR1B;OPRM1;OPRD1;HTR1D GO:0009636| response to toxin HTR1D;CES1 GO:0042220| response to cocaine OPRK1;HTR1B;OPRM1 11120:[DB01183 DB12662] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12662|Naveglitazar PPARG common genes common pathways GO:0030855| epithelial cell differentiation CES1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1 GO:0010033| response to organic substance CREB1;PPARG;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;OPRK1;PPARG GO:0007165| signal transduction OPRK1;TLR4;CREB1;PPARG;OPRD1;OPRM1;ESR1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug CREB1;PPARG;UGT1A1;ABCB1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045087| innate immune response PPARG;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0042594| response to starvation PPARG;UGT1A1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CREB1;TLR4;ESR1 11121:[DB01183 DB03179] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03179|Sinapoyl Coenzyme A COMTD1 common genes common pathways 11122:[DB01183 DB00019] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00019|Pegfilgrastim CSF3R;ELANE common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;CSF3R;TLR4 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ELANE GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ELANE GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ELANE;OPRM1 GO:0045416| positive regulation of interleukin-8 biosynthetic process ELANE;TLR4 GO:0042742| defense response to bacterium TLR4;ELANE 11123:[DB01183 DB09147] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBB;HBA1 GO:0098869| ALB;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;HBB;TLR4 11124:[DB01183 DB00109] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 GO:0097267| CYP2C8;CYP2C19 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C19;CYP2C8 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;CYP2E1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2E1;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4 GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1;UGT1A1 11125:[DB01183 DB02371] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways GO:0045087| innate immune response C1S;TLR4 GO:0002376| immune system process C1S;TLR4 11126:[DB01183 DB02028] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways 11127:[DB01183 DB07209] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;PPARG;ESR1 GO:0042493| response to drug PPARG;CREB1;UGT1A1;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;PPARG GO:0043065| positive regulation of apoptotic process CREB1;PPARG GO:0045087| innate immune response PPARG;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0048511| rhythmic process PPARG;CREB1 GO:0043627| response to estrogen stimulus PPARG;OPRK1;ESR1 GO:0010033| response to organic substance PPARG;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation PPARG;OPRM1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0030855| epithelial cell differentiation CES1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007165| signal transduction TLR4;CREB1;PPARG;OPRK1;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;OPRD1;OPRM1 11128:[DB01183 DB08583] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ABL1;ESR1;OPRM1 GO:0006468| protein phosphorylation CREB1;ABL1 GO:0002322| B cell proliferation involved in immune response ABL1;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;ABL1;TLR4 GO:0070373| negative regulation of ERK1 and ERK2 cascade ABL1;TLR4 GO:0045087| innate immune response ABL1;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;ABL1;TLR4 GO:0043065| positive regulation of apoptotic process ABL1;CREB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;ABL1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ABL1;ESR1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ABL1;ESR1 11129:[DB01183 DB00646] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00646|Nystatin CYP3A4;SLCO1B1;SLCO1B3 common genes CYP3A4 common pathways GO:0015711| organic anion transport SLCO1B3;SLCO1B1;SLCO1A2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0055085| transmembrane transport SLCO1A2;SLCO1B1;SLCO1B3;ABCB1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0006811| ion transport SLCO1A2;SLCO1B3;SLCO1B1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 11130:[DB01183 DB00222] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;ABCC8;OPRM1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;KCNJ11;ABCC8 GO:0032760| positive regulation of tumor necrosis factor production TLR4;ABCC8 GO:0008542| visual learning CREB1;ABCC8 GO:0007613| memory CREB1;ABCC8 GO:0006810| transport ABCB1;ABCB11 GO:0032355| response to estradiol stimulus KCNJ11;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 GO:0007165| signal transduction ABCC8;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0032868| response to insulin stimulus ABCC8;OPRK1 GO:0055085| transmembrane transport ABCC8;ABCB11;KCNJ11;SLCO1A2;ABCB1 GO:0006811| ion transport KCNJ1;SLCO1A2;KCNJ11 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;ALB 11131:[DB01183 DB00721] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0007626| locomotory behavior OPRM1;OPRK1;SLC6A3 GO:0043065| positive regulation of apoptotic process CREB1;KCNMA1 GO:0071361| cellular response to ethanol UGT1A1;KCNMB1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;UGT1A1;MAOB GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN3A;OPRM1;CHRNA2 GO:0045471| response to ethanol HTR3A;SLC6A3;OPRK1;MAOB;UGT1A1;GRIN3A;OPRM1 GO:0019233| sensory perception of pain OPRK1;SCN10A;OPRD1;OPRM1 GO:0007595| lactation SLC6A3;CREB1 GO:0035094| response to nicotine CREB1;SLC6A3;CHRNA2 GO:0007600| sensory perception OPRM1;SCN10A;OPRK1 GO:0007268| synaptic transmission KCNMB1;KCNMB3;HTR3A;OPRK1;OPRM1;KCNMB4;OPRD1;KCNMB2;KCNN1 GO:0042493| response to drug ABCB1;SLC6A3;UGT1A1;MAOB;BCHE;CREB1 GO:0055114| oxidation-reduction process MAOA;CYP3A4;MAOB;CYP2C8 GO:0070588| calcium ion transmembrane transport OPRM1;GRIN3A GO:0002376| immune system process KCNN4;TLR4 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0007165| signal transduction ESR1;OPRM1;OPRD1;CHRNA2;CREB1;TLR4;OPRK1;HTR3A GO:0071363| cellular response to growth factor stimulus OPRD1;HTR3A;CREB1 GO:1901381| OPRK1;KCNMB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0045332| phospholipid translocation ABCB1;KCNN4 GO:0071456| cellular response to hypoxia KCNMB1;OPRD1 GO:0040018| positive regulation of multicellular organism growth SLC6A3;CREB1 GO:0007568| aging CREB1;KCNMB1;SLC6A3 GO:0001666| response to hypoxia CREB1;KCNMA1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE GO:0006811| ion transport KCNN3;KCNMB3;HTR3A;GRIN3A;SCN10A;KCNN4;KCNMB1;KCNN1;KCNN2;CHRNA2;KCNMA1;KCNMB4;KCNMB2;SLCO1A2 GO:0009636| response to toxin MAOB;CES1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0055085| transmembrane transport SLCO1A2;KCNMA1;ABCB1;SLC6A3;SCN10A GO:0042220| response to cocaine OPRM1;OPRK1;SLC6A3;HTR3A 11132:[DB01183 DB03932] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03932|LFA703 ITGAL common genes common pathways GO:0006954| inflammatory response TLR4;ITGAL GO:0007165| signal transduction ESR1;ITGAL;OPRM1;OPRD1;OPRK1;CREB1;TLR4 11133:[DB01183 DB01195] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C9;CYP2D6;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C8;CYP2D6 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP2D6;CYP3A4 GO:1901381| OPRK1;KCNH2 GO:0008202| steroid metabolic process CYP2C9;UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0055085| transmembrane transport SCN5A;KCNH2;SLCO1A2;ABCB1;SCN4A GO:0006811| ion transport SCN5A;KCNH2;SLCO1A2;SCN4A 11134:[DB01183 DB11071] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug CREB1;UGT1A1;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4;CYP2C8 GO:0006954| inflammatory response PTGS2;PTGS1;TLR4 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;PTGS2;OPRM1 GO:0019233| sensory perception of pain OPRK1;PTGS2;OPRM1;OPRD1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;PTGS1;CES1;CYP3A4 GO:0009314| response to radiation PTGS2;OPRM1;OPRK1 GO:0050727| regulation of inflammatory response PTGS2;ESR1;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;CREB1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0007568| aging CREB1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007613| memory CREB1;PTGS2 GO:0098869| ALB;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TLR4 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 11135:[DB01183 DB08191] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways GO:0006468| protein phosphorylation CREB1;SGK1 GO:0042981| regulation of apoptotic process ESR1;CREB1;SGK1 11136:[DB01183 DB13257] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes common pathways GO:0007568| aging CREB1;PTGS2;CAT;MPO GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0007613| memory PTGS2;CREB1 GO:0071363| cellular response to growth factor stimulus CREB1;OPRD1;CAT GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1;CAT GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0097267| CYP2C8;CYP4A11 GO:0098869| PTGS2;PTGS1;CAT;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TLR4 GO:0044267| cellular protein metabolic process TF;CP;ALB GO:0001895| retina homeostasis ALB;TF GO:0032868| response to insulin stimulus OPRK1;CAT GO:0009636| response to toxin CAT;CES1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0006811| ion transport TF;SLCO1A2;CP GO:0014823| response to activity CREB1;CAT GO:0010033| response to organic substance PTGS2;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation FTH1;PTGS2;OPRM1 GO:0001666| response to hypoxia CAT;NOS2;CREB1 GO:0008584| male gonad development ESR1;RRM1 GO:0045600| positive regulation of fat cell differentiation CREB1;TPH1 GO:0006351| transcription, DNA-dependent ESR1;PCBD1;CREB1 GO:0001889| liver development ACO2;UGT1A1 GO:0019233| sensory perception of pain PTGS2;OPRM1;OPRD1;OPRK1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;CAT GO:0032496| response to lipopolysaccharide NOS2;TLR4;UGT1A1;OPRM1;PTGS2;MPO GO:0007623| circadian rhythm TPH1;CREB1;NOS2 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:1900745| XDH;OPRK1 GO:0060749| mammary gland alveolus development TPH1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2;CAT;MPO GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CES1;CYP2C8 GO:0008152| metabolic process CES1;UGT1A1;RRM1;ACO2 GO:0019373| epoxygenase P450 pathway CYP4A11;CYP2C8 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1;CAT GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;NOS2 GO:0050829| defense response to Gram-negative bacterium TLR4;NOS2 GO:0002576| platelet degranulation ALB;TF GO:0043065| positive regulation of apoptotic process CREB1;PTGS2 GO:0050727| regulation of inflammatory response TLR4;PTGS2;ESR1 GO:0042742| defense response to bacterium TLR4;NOS2;MPO GO:0043687| post-translational protein modification TF;CP;ALB GO:0055114| oxidation-reduction process NDUFS8;NOS2;SUOX;CYP2C8;RRM1;TPH1;P4HA1;SDHA;TMLHE;CYP3A4;XDH;CYP4A11;PTGS2;CAT;CP;PTGS1;MPO;PCBD1;FTH1 GO:0009617| response to bacterium NOS2;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;PCBD1 GO:0032094| response to food MPO;OPRM1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;PCBD1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CAT;PTGS2 GO:0010629| negative regulation of gene expression CREB1;NOS2;XDH;OPRD1;ESR1 GO:0007595| lactation CREB1;XDH GO:0006955| immune response TLR4;OPRK1;OPRD1;FTH1 GO:0006954| inflammatory response PTGS2;PTGS1;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TLR4 11137:[DB01183 DB05232] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways GO:0055085| transmembrane transport SCN2A;SCN3A;ABCB1;SCN1A;SLCO1A2;SCN8A GO:0006811| ion transport SCN3A;SCN2A;SCN1A;SLCO1A2;SCN8A 11138:[DB01183 DB03851] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03851|Carbazole Butanoic Acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response FABP4;ESR1;TLR4 GO:0050729| positive regulation of inflammatory response TLR4;FABP4 11139:[DB01183 DB00056] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;CD33 GO:1904646| FCGR2B;TLR4 GO:0007165| signal transduction CD33;OPRD1;FCGR2C;OPRM1;ESR1;OPRK1;FCGR1A;TLR4;FCGR2B;CREB1 GO:0002376| immune system process TLR4;C1QB;C1R;FCGR1A;FCGR2A;C1QC;C1S;C1QA GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0009617| response to bacterium FCGR2B;TLR4 GO:0006954| inflammatory response FCGR2B;TLR4 GO:0016032| viral reproduction CREB1;FCGR2B GO:0006955| immune response FCGR3A;FCGR2C;OPRD1;C1QC;C1R;FCGR3B;FCGR2B;TLR4;FCGR1A;OPRK1 GO:0046330| positive regulation of JNK cascade TLR4;FCGR2B GO:0045087| innate immune response C1QA;C1S;C1QC;FCGR1A;C1QB;C1R;TLR4 11140:[DB01183 DB08478] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug ABCB1;TYMS;CREB1;UGT1A1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1;TYMS GO:0007623| circadian rhythm CREB1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0009636| response to toxin TYMS;CES1 GO:0007568| aging CREB1;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 11141:[DB01183 DB07931] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes ESR1 common pathways GO:0030855| epithelial cell differentiation AKR1C1;CES1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0010628| positive regulation of gene expression NR1I2;TLR4 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0015721| bile acid and bile salt transport SLCO1A2;AKR1C1;ALB GO:0008584| male gonad development ESR1 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0008202| steroid metabolic process CYP2C8;NR1I2;UGT1A1;CYP3A4 GO:0032355| response to estradiol stimulus ESR1 GO:0002064| epithelial cell development ESR1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;NR1I3;CREB1;TLR4;NR1I2;OPRK1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;TLR4 GO:1903799| ESR1 GO:0055114| oxidation-reduction process CYP3A4;AKR1C1;CYP2C8 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CREB1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I3;CREB1;NR1I2 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0010629| negative regulation of gene expression CREB1;OPRD1;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;NR1I2;CYP3A4 GO:0048863| stem cell differentiation ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I3;ESR1;NR1I2 GO:0001547| antral ovarian follicle growth ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0006351| transcription, DNA-dependent NR1I3;ESR1;NR1I2;CREB1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway NR1I3;ESR1;NR1I2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;OPRK1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0007586| digestion UGT1A1;AKR1C1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1 GO:0060065| uterus development ESR1 GO:0006805| xenobiotic metabolic process CYP3A4;AKR1C1;CES1;CYP2C8;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;NR1I2;TLR4;NR1I3;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 11142:[DB01183 DB07112] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways GO:0001666| response to hypoxia CREB1;EGLN1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity EGLN1;ESR1 GO:0055114| oxidation-reduction process CYP2C8;EGLN1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;EGLN1;TLR4;CREB1 11143:[DB01183 DB01827] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways GO:0045087| innate immune response LGALS3;TLR4 GO:0002376| immune system process LGALS3;TLR4 GO:0030154| cell differentiation LGALS3;CREB1 GO:0030855| epithelial cell differentiation CES1;LGALS3 11144:[DB01183 DB11219] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes ESR1 common pathways GO:0030879| mammary gland development PGR;CREB1 GO:0006366| transcription from RNA polymerase II promoter CREB1;ESR1 GO:0008584| male gonad development AR;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0060523| prostate epithelial cord elongation ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0043627| response to estrogen stimulus OPRK1;ESR1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination AR;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0032355| response to estradiol stimulus ESR1 GO:0006338| chromatin remodeling ESR1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR2;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;OPRM1 GO:0006810| transport ABCB1;AR GO:1903799| ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;AR;TLR4;CREB1;PGR;OPRK1;ESR2 GO:0002064| epithelial cell development ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1;CREB1;PGR GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;PGR;ESR2;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;CREB1;ESR2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PGR;ESR2;AR;ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0048863| stem cell differentiation ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRM1;OPRD1;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;PGR;ESR1;AR GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1;PGR;ESR2 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;PGR;ESR2;TLR4;CREB1 GO:0060065| uterus development ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;AR;ESR1 GO:0042981| regulation of apoptotic process CREB1;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly CREB1;ESR1 GO:0060749| mammary gland alveolus development ESR1;AR 11145:[DB01183 DB03732] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03732|Etheno-Nadp BST1 common genes common pathways GO:0030890| positive regulation of B cell proliferation BST1;TLR4 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;BST1;OPRK1;TLR4;CREB1 GO:0050727| regulation of inflammatory response BST1;TLR4;ESR1 11146:[DB01183 DB05183] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05183|MLN0415 IKBKB common genes common pathways GO:0045087| innate immune response TLR4;IKBKB GO:0043066| negative regulation of apoptotic process ALB;IKBKB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKB;CREB1;TLR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKB;TLR4 GO:0002756| MyD88-independent toll-like receptor signaling pathway TLR4;IKBKB GO:0007252| I-kappaB phosphorylation IKBKB;TLR4 GO:0006954| inflammatory response TLR4;IKBKB GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKB;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent IKBKB;ESR1;CREB1 GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKB;TLR4 GO:0006468| protein phosphorylation CREB1;IKBKB GO:0035666| TRIF-dependent toll-like receptor signaling pathway TLR4;IKBKB 11147:[DB01183 DB03382] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways GO:0010033| response to organic substance SOD1;UGT1A1;CREB1 GO:0001895| retina homeostasis SOD1;ALB GO:0000187| activation of MAPK activity TLR4;SOD1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0007568| aging CREB1;SOD1 GO:0055114| oxidation-reduction process CYP2C8;SOD1;CYP3A4 GO:0042493| response to drug SOD1;ABCB1;CREB1;UGT1A1 GO:0043066| negative regulation of apoptotic process SOD1;ALB GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0043065| positive regulation of apoptotic process SOD1;CREB1 GO:0002576| platelet degranulation ALB;SOD1 GO:0045471| response to ethanol UGT1A1;OPRK1;SOD1;OPRM1 11148:[DB01183 DB08790] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;HPGDS;CREB1;TLR4;OPRK1 GO:0007626| locomotory behavior OPRK1;HPGDS;OPRM1 GO:0006629| lipid metabolic process CYP3A4;HPGDS 11149:[DB01183 DB07940] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07940|9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE BCHE common genes common pathways GO:0042493| response to drug ABCB1;CREB1;BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007584| response to nutrient BCHE;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;BCHE 11150:[DB01183 DB03935] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;FGF2;CREB1 GO:0043086| negative regulation of catalytic activity UGT1A1;ANXA5 GO:0042060| wound healing OPRM1;FGF2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;ESR1;FGF2 GO:0002576| platelet degranulation ANXA5;ALB GO:0043066| negative regulation of apoptotic process ANXA5;ALB GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF2;OPRM1;TLR4 GO:0000187| activation of MAPK activity FGF2;TLR4 GO:0010033| response to organic substance ANXA5;CREB1;UGT1A1 GO:0030154| cell differentiation CREB1;FGF2 GO:0072089| stem cell proliferation ABCB1;FGF2 GO:0007165| signal transduction FGF2;OPRM1;OPRD1;ESR1;ANXA5;CREB1;TLR4;OPRK1 GO:0010863| positive regulation of phospholipase C activity ESR1;FGF2 11151:[DB01183 DB01746] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways GO:0030154| cell differentiation CREB1;SLC7A5 GO:0006810| transport ABCB1;SLC7A5 GO:0055085| transmembrane transport SLC16A10;SLCO1A2;ABCB1 11152:[DB01183 DB09031] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09031|Miltefosine ABCB1;PLD1 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PLD1 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;CREB1;UGT1A1 11153:[DB01183 DB08429] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways GO:0001666| response to hypoxia CREB1;DPP4 11154:[DB01183 DB02217] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02217|Dpb-T NT5M common genes common pathways 11155:[DB01183 DB01406] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes ESR1;CYP3A4 common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;ESR1 GO:0042737| drug catabolic process CYP3A4 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0043401| steroid hormone mediated signaling pathway AR;ESR1;PGR GO:0006351| transcription, DNA-dependent ESR1;AR;CREB1;PGR GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development AR;ESR1 GO:0042981| regulation of apoptotic process ESR1;CREB1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0050727| regulation of inflammatory response ESR1;TLR4 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;CCL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;TLR4;CREB1;PGR GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0060065| uterus development CYP19A1;ESR1 GO:0031663| lipopolysaccharide-mediated signaling pathway CCL2;TLR4 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0009617| response to bacterium CCL2;TLR4 GO:0043491| protein kinase B signaling cascade CREB1;CCL2 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;CYP2C8 GO:0010629| negative regulation of gene expression OPRD1;ESR1;PGR;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;CREB1;PGR GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;ESR1;AR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR;PGR GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;AR GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0006954| inflammatory response TLR4;CCL2 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0006955| immune response OPRD1;OPRK1;TLR4;CCL2 GO:0001547| antral ovarian follicle growth ESR1 GO:0006468| protein phosphorylation CREB1;CCL2 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0006810| transport ABCB1;AR GO:0032355| response to estradiol stimulus ESR1 GO:0007186| G-protein coupled receptor signaling pathway CCL2;GNRHR;OPRK1;GNRHR2;OPRM1;OPRD1 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process CCL2;TLR4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0007165| signal transduction CREB1;CCL2;TLR4;GNRHR;OPRK1;PGR;GNRHR2;ESR1;OPRM1;OPRD1;AR GO:0002064| epithelial cell development ESR1 GO:1903799| ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;ESR1;TLR4 GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0036378| CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TLR4;CCL2;OPRM1 GO:0030879| mammary gland development CYP19A1;CREB1;PGR GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CCL2 GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;AR GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1;AR GO:0008584| male gonad development AR;ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0042359| vitamin D metabolic process CYP3A4 GO:0010628| positive regulation of gene expression AR;TLR4 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 11156:[DB01183 DB09552] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB09552|Thonzonium ATP6V1C1 common genes common pathways GO:0006811| ion transport SLCO1A2;ATP6V1C1 11157:[DB01183 DB03480] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03480|Brequinar Analog DHODH common genes common pathways GO:0007595| lactation DHODH;CREB1 GO:0055114| oxidation-reduction process CYP3A4;DHODH;CYP2C8 GO:0042493| response to drug DHODH;ABCB1;UGT1A1;CREB1 GO:0042594| response to starvation UGT1A1;DHODH GO:0043065| positive regulation of apoptotic process CREB1;DHODH GO:0014070| response to organic cyclic compound UGT1A1;DHODH 11158:[DB01183 DB04531] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04531|Benzylcysteine MGMT common genes common pathways GO:0009636| response to toxin MGMT;CES1 GO:0014070| response to organic cyclic compound UGT1A1;MGMT GO:0042493| response to drug CREB1;UGT1A1;ABCB1;MGMT GO:0045471| response to ethanol MGMT;OPRM1;UGT1A1;OPRK1 GO:0043066| negative regulation of apoptotic process MGMT;ALB 11159:[DB01183 DB01625] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01625|Isopropamide CHRM3;CHRM4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;CHRM4;CHRM3 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CHRM4;CREB1;TLR4;CHRM3 GO:0007586| digestion UGT1A1;CHRM3 11160:[DB01183 DB05035] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05035|Eprotirome THRA;THRB common genes common pathways GO:0006366| transcription from RNA polymerase II promoter CREB1;THRA;ESR1 GO:0006351| transcription, DNA-dependent ESR1;THRA;CREB1;THRB GO:0043401| steroid hormone mediated signaling pathway ESR1;THRA;THRB GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;THRA;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;THRA;CREB1;TLR4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;THRB;CREB1;THRA GO:0060509| Type I pneumocyte differentiation THRA;CREB1;THRB GO:0006367| transcription initiation from RNA polymerase II promoter THRB;THRA;ESR1 11161:[DB01183 DB03782] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03782|N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea PLAU common genes common pathways GO:0001666| response to hypoxia CREB1;PLAU GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;PLAU;CREB1;TLR4 11162:[DB01183 DB11079] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0098869| ALB;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TLR4 GO:0007568| aging CREB1;PTGS2 GO:0007613| memory CREB1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0010033| response to organic substance PTGS2;UGT1A1;CREB1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0050727| regulation of inflammatory response TLR4;PTGS2;ESR1 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRD1;PTGS2;OPRM1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;OPRM1;PTGS2 GO:0006954| inflammatory response TLR4;PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1;CYP2C8 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;PTGS2 11163:[DB01183 DB02300] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;VDR GO:0007595| lactation CREB1;VDR GO:0032094| response to food MPO;OPRM1 GO:0006355| regulation of transcription, DNA-dependent ESR1;VDR;CREB1 GO:0060745| mammary gland branching involved in pregnancy ESR1;VDR GO:0055114| oxidation-reduction process CYP2C8;MPO;CYP24A1;CYP3A4 GO:0042742| defense response to bacterium TLR4;MPO GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;ESR1;CREB1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;VDR GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;OPRM1;MPO GO:0043401| steroid hormone mediated signaling pathway VDR;ESR1 GO:0006351| transcription, DNA-dependent ESR1;VDR;CREB1 GO:0042359| vitamin D metabolic process CYP24A1;CYP3A4 GO:0010628| positive regulation of gene expression TLR4;VDR GO:0008285| negative regulation of cell proliferation VDR;OPRM1 GO:0007165| signal transduction OPRK1;TLR4;CREB1;VDR;ESR1;OPRD1;OPRM1 GO:0007568| aging MPO;CREB1 11164:[DB01183 DB08313] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08313|nocodazole HPGDS common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR1;OPRD1;OPRM1;HPGDS GO:0006629| lipid metabolic process CYP3A4;HPGDS GO:0007626| locomotory behavior OPRK1;HPGDS;OPRM1 11165:[DB01183 DB04752] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR5A1;ESR1;TLR4;CREB1 GO:0006351| transcription, DNA-dependent NR5A1;ESR1;CREB1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR5A1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;NR5A1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR5A1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;NR5A1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR1;NR5A1 GO:0030154| cell differentiation CREB1;NR5A1 GO:0010628| positive regulation of gene expression TLR4;NR5A1 GO:0008584| male gonad development NR5A1;ESR1 GO:0006366| transcription from RNA polymerase II promoter NR5A1;ESR1;CREB1 11166:[DB01183 DB12747] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB12747|Tertomotide TERT common genes common pathways GO:0071456| cellular response to hypoxia TERT;OPRD1 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1;TERT GO:0051000| positive regulation of nitric-oxide synthase activity ESR1;TERT GO:0043066| negative regulation of apoptotic process ALB;TERT 11167:[DB01183 DB13170] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13170|Plecanatide GUCY1A2 common genes common pathways GO:0007165| signal transduction ESR1;OPRM1;OPRD1;OPRK1;CREB1;GUCY1A2;TLR4 11168:[DB01183 DB01073] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;OPRM1 GO:0008152| metabolic process CES1;RRM1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;RRM1;CYP3A4 GO:0007595| lactation SLC29A1;CREB1 GO:0016032| viral reproduction CREB1;POLA1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1 GO:0008584| male gonad development RRM1;ESR1 11169:[DB01183 DB03983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;SUOX;CYP3A4 11170:[DB01183 DB00092] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways GO:0009617| response to bacterium TLR4;FCGR2B GO:0032760| positive regulation of tumor necrosis factor production CD2;TLR4 GO:0006954| inflammatory response FCGR2B;TLR4 GO:0006955| immune response OPRD1;FCGR2C;FCGR3A;C1QC;C1R;FCGR2B;FCGR3B;TLR4;FCGR1A;OPRK1 GO:0016032| viral reproduction CREB1;FCGR2B GO:0046330| positive regulation of JNK cascade FCGR2B;TLR4 GO:0045087| innate immune response C1QC;C1QA;C1R;C1QB;TLR4;FCGR1A GO:1904646| FCGR2B;TLR4 GO:0007165| signal transduction ESR1;OPRM1;FCGR2C;OPRD1;FCGR1A;OPRK1;FCGR2B;CREB1;TLR4 GO:0002376| immune system process C1R;C1QB;TLR4;FCGR2A;FCGR1A;C1QC;C1QA GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A 11171:[DB01183 DB07974] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07974|1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE F10 common genes common pathways 11172:[DB01183 DB13983] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0006811| ion transport GABRA1;GABRA6;GABRA4;GABRG2;SLCO1A2;GABRG3;GABRA3;GABRA5;GABRG1;GABRA2 GO:0007165| signal transduction GABRA6;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1;GABRA5 GO:0006810| transport GABRG2;GABRA1;GABRA6;GABRA4;GABRA3;GABRA5;ABCB1 GO:0042493| response to drug GABRG3;ABCB1;CREB1;UGT1A1 GO:0007268| synaptic transmission GABRG2;OPRD1;OPRM1;GABRA5;GABRG1;OPRK1 11173:[DB01183 DB08383] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways GO:0008152| metabolic process UGT1A1;CES1;PDE10A GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PDE10A;OPRK1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;ESR1;OPRM1;OPRD1;PDE10A 11174:[DB01183 DB02895] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways GO:0098869| ALB;GSR GO:0055114| oxidation-reduction process CYP3A4;GSR;CYP2C8 11175:[DB01183 DB06766] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06766|Alcaftadine HRH1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRD1;HRH1;OPRM1 GO:0007613| memory HRH1;CREB1 GO:0007165| signal transduction CREB1;TLR4;OPRK1;OPRM1;HRH1;OPRD1;ESR1 GO:0006954| inflammatory response TLR4;HRH1 GO:0008542| visual learning CREB1;HRH1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;ESR1;OPRK1 11176:[DB01183 DB02967] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02967|N-Ethylmaleimide CLC common genes common pathways 11177:[DB01183 DB00484] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;AOX1;CYP2C8 GO:0000187| activation of MAPK activity TLR4;ADRA2B GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADRA2C;OPRK1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRK1;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;ADRA2A;OPRD1;OPRM1;ADRA2B;ADRA2C GO:0017144| drug metabolic process AOX1;UGT1A1;CYP2C8;CYP3A4 GO:0007165| signal transduction OPRK1;ADRA2A;TLR4;CREB1;OPRD1;OPRM1;ADRA2B;ESR1;ADRA2C GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 11178:[DB01183 DB01954] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01954|Rolipram PDE4D;PDE4B common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;PDE4D;OPRM1;OPRK1;PDE4B GO:0007568| aging PDE4D;CREB1 GO:0007165| signal transduction OPRM1;OPRD1;PDE4D;ESR1;CREB1;TLR4;PDE4B;OPRK1 GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4;PDE4B GO:0071222| cellular response to lipopolysaccharide OPRK1;PDE4B;TLR4;PDE4D 11179:[DB01183 DB05207] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0010628| positive regulation of gene expression TLR4;TNF GO:0010033| response to organic substance UGT1A1;CREB1;TNF GO:0000187| activation of MAPK activity TNF;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TNF;TLR4 GO:0032715| negative regulation of interleukin-6 production TNF;TLR4 GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;TLR4 GO:0032755| positive regulation of interleukin-6 production TLR4;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;TNF;OPRM1;ESR1 GO:0032757| positive regulation of interleukin-8 production TLR4;TNF GO:0032722| positive regulation of chemokine production TLR4;TNF GO:0007165| signal transduction OPRD1;OPRM1;ESR1;IL1R1;OPRK1;TLR4;CREB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;TNF GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0006955| immune response OPRD1;OPRK1;IL1R1;TNF;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;ESR1 GO:0006954| inflammatory response TLR4;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TLR4 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CREB1;TNF GO:0045416| positive regulation of interleukin-8 biosynthetic process TLR4;TNF GO:0010629| negative regulation of gene expression OPRD1;ESR1;CREB1;TNF GO:0042742| defense response to bacterium TNF;TLR4 GO:0043491| protein kinase B signaling cascade CREB1;TNF GO:0031663| lipopolysaccharide-mediated signaling pathway TNF;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TNF;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TNF;TLR4;ESR1 GO:0071222| cellular response to lipopolysaccharide OPRK1;TNF;TLR4 GO:0043065| positive regulation of apoptotic process CREB1;TNF GO:0045672| positive regulation of osteoclast differentiation TNF;CREB1 GO:0050727| regulation of inflammatory response ESR1;IL1R1;TNF;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;ESR1 GO:0032729| positive regulation of interferon-gamma production TLR4;TNF GO:0046330| positive regulation of JNK cascade TLR4;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0097190| apoptotic signaling pathway TNF;TLR4 11180:[DB01183 DB06677] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06677|Clazosentan EDNRA common genes common pathways GO:0001666| response to hypoxia EDNRA;CREB1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1;EDNRA GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;OPRM1;ESR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;EDNRA;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;EDNRA;OPRD1;OPRM1 11181:[DB01183 DB04258] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04258|Seocalcitol VDR common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter VDR;ESR1 GO:0007595| lactation CREB1;VDR GO:0060745| mammary gland branching involved in pregnancy VDR;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;VDR;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;ESR1;CREB1;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;VDR GO:0006351| transcription, DNA-dependent CREB1;ESR1;VDR GO:0010628| positive regulation of gene expression TLR4;VDR GO:0008285| negative regulation of cell proliferation OPRM1;VDR GO:0007165| signal transduction VDR;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 11182:[DB01183 DB01188] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0006811| ion transport SLCO1A2;ATP1A1 GO:0071260| cellular response to mechanical stimulus TLR4;ATP1A1 GO:0042493| response to drug ATP1A1;ABCB1;CREB1;UGT1A1 11183:[DB01183 DB11221] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11221|Dioxybenzone SHBG common genes common pathways 11184:[DB01183 DB06548] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;FDPS;GGPS1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction CREB1;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS;UGT1A1;CYP2C8 11185:[DB01183 DB00045] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00045|Lyme disease vaccine (recombinant OspA) TLR2 common genes common pathways GO:0032735| positive regulation of interleukin-12 production TLR2;TLR4 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process TLR2;TLR4 GO:0050729| positive regulation of inflammatory response TLR4;TLR2 GO:0002224| toll-like receptor signaling pathway TLR4;TLR2 GO:0032757| positive regulation of interleukin-8 production TLR4;TLR2 GO:0002376| immune system process TLR4;TLR2 GO:0032755| positive regulation of interleukin-6 production TLR2;TLR4 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;TLR2;CREB1 GO:0032728| positive regulation of interferon-beta production TLR4;TLR2 GO:0032722| positive regulation of chemokine production TLR4;TLR2 GO:0009636| response to toxin TLR2;CES1 GO:0032868| response to insulin stimulus OPRK1;TLR2 GO:0001666| response to hypoxia TLR2;CREB1 GO:0010628| positive regulation of gene expression TLR2;TLR4 GO:0008285| negative regulation of cell proliferation OPRM1;TLR2 GO:0032496| response to lipopolysaccharide TLR4;TLR2;UGT1A1;OPRM1 GO:0071223| cellular response to lipoteichoic acid TLR4;TLR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR2;TLR4 GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;TLR2 GO:0002755| MyD88-dependent toll-like receptor signaling pathway TLR2;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;TLR2 GO:0045087| innate immune response TLR4;TLR2 GO:0032733| positive regulation of interleukin-10 production TLR4;TLR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TLR2 GO:0006954| inflammatory response TLR2;TLR4 GO:0007252| I-kappaB phosphorylation TLR2;TLR4 GO:0050707| regulation of cytokine secretion TLR4;TLR2 GO:0006955| immune response OPRD1;OPRK1;TLR2;TLR4 GO:0032760| positive regulation of tumor necrosis factor production TLR2;TLR4 11186:[DB01183 DB04372] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 11187:[DB01183 DB00905] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGFR GO:0000060| protein import into nucleus, translocation AKR1C3;OPRD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;PTGER3;OPRM1;ESR1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;PTGFR;OPRM1;PTGER1 GO:0055114| oxidation-reduction process CYP3A4;AKR1C3;CYP2C8 GO:0007165| signal transduction OPRK1;CREB1;TLR4;PTGFR;OPRM1;PTGER1;PTGER3;OPRD1;ESR1 GO:0009267| cellular response to starvation ALB;AKR1C3 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;AKR1C3;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;PTGFR GO:0007186| G-protein coupled receptor signaling pathway OPRD1;PTGER3;AKR1C3;OPRM1;PTGER1;PTGFR;OPRK1 GO:0007584| response to nutrient UGT1A1;AKR1C3 GO:0010628| positive regulation of gene expression TLR4;PTGFR GO:0008584| male gonad development ESR1;AKR1C3 11188:[DB01183 DB00466] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways GO:0009267| cellular response to starvation ALB;GLUL GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP1A1;CYP3A4 GO:0007568| aging CREB1;CYP1A1 GO:0006810| transport GABRR1;GABRA1;ABCB1 GO:0097267| CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP2C8;CYP1A1;UGT1A1;CYP3A4 GO:0006811| ion transport GLRA1;GLRA2;GABRA1;GLRA3;GABRR1;SLCO1A2 GO:0002933| CYP3A4;CYP2C8;CYP1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0009636| response to toxin CYP1A1;CES1 GO:0001666| response to hypoxia CYP1A1;CREB1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance CREB1;CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1;CYP1A1;TLR4 GO:0071294| cellular response to zinc ion CREB1;GLRA1;GLRA2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;GLRA2;GLRA1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;GLRA3;GLRA2;GLRA1;OPRK1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C8 GO:0071361| cellular response to ethanol GLRA2;GLRA1;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;CYP1A1 GO:0007268| synaptic transmission OPRK1;GLRA1;GLRA2;OPRD1;OPRM1;GLRA3;GABRR1 GO:0032094| response to food OPRM1;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP1A1 11189:[DB01183 DB01078] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01078|Deslanoside ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus TLR4;ATP1A1 GO:0042493| response to drug UGT1A1;CREB1;ABCB1;ATP1A1 GO:0006811| ion transport SLCO1A2;ATP1A1 11190:[DB01183 DB11945] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11945|Avelumab CD274 common genes common pathways GO:0006955| immune response OPRD1;CD274;TLR4;OPRK1 GO:0007165| signal transduction ESR1;OPRD1;OPRM1;OPRK1;TLR4;CD274;CREB1 GO:0032689| negative regulation of interferon-gamma production TLR4;CD274 11191:[DB01183 DB01786] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01786|D-Alanine SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC16A10 11192:[DB01183 DB04451] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CTSV GO:0008584| male gonad development ESR1;CTSV GO:0009267| cellular response to starvation ALB;CTSV GO:0051384| response to glucocorticoid stimulus CTSV;UGT1A1 11193:[DB01183 DB01225] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways GO:0044267| cellular protein metabolic process ALB;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0007584| response to nutrient UGT1A1;SERPINC1 GO:0007568| aging MPO;CREB1 GO:0032094| response to food MPO;OPRM1 GO:0055114| oxidation-reduction process MPO;CYP3A4;CYP2C8 GO:0043687| post-translational protein modification SERPINC1;ALB GO:0042742| defense response to bacterium MPO;TLR4 GO:0007595| lactation CREB1;SERPINC1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MPO;OPRM1 GO:0043066| negative regulation of apoptotic process ALB;MPO 11194:[DB01183 DB06258] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06258|Bimoclomol HSF1 common genes common pathways GO:0007584| response to nutrient HSF1;UGT1A1 GO:0014823| response to activity HSF1;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;HSF1 GO:0010628| positive regulation of gene expression HSF1;TLR4 GO:0014070| response to organic cyclic compound UGT1A1;HSF1 GO:0032720| negative regulation of tumor necrosis factor production HSF1;TLR4 GO:0071392| cellular response to estradiol stimulus UGT1A1;HSF1;ESR1 GO:0006468| protein phosphorylation HSF1;CREB1 GO:0040018| positive regulation of multicellular organism growth CREB1;HSF1 GO:0032355| response to estradiol stimulus ESR1;HSF1 GO:1901215| HSF1;CREB1 GO:0006355| regulation of transcription, DNA-dependent CREB1;HSF1;ESR1 GO:0010629| negative regulation of gene expression CREB1;HSF1;ESR1;OPRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HSF1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;TLR4;HSF1;ESR1 GO:0071222| cellular response to lipopolysaccharide HSF1;TLR4;OPRK1 GO:0006351| transcription, DNA-dependent ESR1;HSF1;CREB1 GO:0032496| response to lipopolysaccharide HSF1;OPRM1;UGT1A1;TLR4 11195:[DB01183 DB01260] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01260|Desonide NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR3C1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;ESR1;NR3C1 GO:0071560| cellular response to transforming growth factor beta stimulus CREB1;NR3C1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CES1 GO:0042737| drug catabolic process CYP3A4 GO:0006351| transcription, DNA-dependent CREB1;ESR1;NR3C1 GO:0043401| steroid hormone mediated signaling pathway ESR1;NR3C1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;ESR1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0006355| regulation of transcription, DNA-dependent NR3C1;ESR1;CREB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;NR3C1;OPRM1;ESR1 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0006366| transcription from RNA polymerase II promoter NR3C1;ESR1;CREB1 GO:0002933| CYP2C8;CYP3A4 11196:[DB01183 DB05624] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05624|Teverelix GNRHR common genes common pathways GO:0007165| signal transduction TLR4;CREB1;OPRK1;GNRHR;OPRD1;OPRM1;ESR1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GNRHR;OPRD1;OPRM1 11197:[DB01183 DB02929] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02929|K201 ANXA5 common genes common pathways GO:0010033| response to organic substance ANXA5;CREB1;UGT1A1 GO:0007165| signal transduction ANXA5;ESR1;OPRD1;OPRM1;OPRK1;TLR4;CREB1 GO:0043086| negative regulation of catalytic activity ANXA5;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB;ANXA5 GO:0002576| platelet degranulation ALB;ANXA5 11198:[DB01183 DB04020] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR2;UGT1A1;ESR1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;ESR2;ESR1;OPRD1;OPRM1 GO:0006355| regulation of transcription, DNA-dependent CREB1;ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2 GO:0006351| transcription, DNA-dependent ESR2;CREB1;ESR1 GO:0030520| intracellular estrogen receptor signaling pathway ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TLR4;CREB1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2 11199:[DB01183 DB05119] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05119|Rilapladib PLA2G7 common genes common pathways GO:0050729| positive regulation of inflammatory response PLA2G7;TLR4 GO:0006629| lipid metabolic process CYP3A4;PLA2G7 11200:[DB01183 DB11770] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11770|Talinolol CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2D6;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 11201:[DB01183 DB07723] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0042752| regulation of circadian rhythm PPARG;CREB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042493| response to drug ABCB1;UGT1A1;CREB1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;CREB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;CREB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0045087| innate immune response TLR4;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0006629| lipid metabolic process PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PPARG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TLR4;CREB1;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG;OPRK1 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0048511| rhythmic process PPARG;CREB1 GO:0008285| negative regulation of cell proliferation OPRM1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;CREB1 GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG GO:0030855| epithelial cell differentiation PPARG;CES1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;PPARG;TLR4;OPRK1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;PPARG;OPRK1 11202:[DB01183 DB08038] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 11203:[DB01183 DB04711] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04711|Iodipamide ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB 11204:[DB01183 DB03510] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways GO:0042594| response to starvation UGT1A1;ADSSL1 GO:0002376| immune system process ADSSL1;TLR4 11205:[DB01183 DB01065] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes ESR1 common pathways GO:0007568| aging MPO;CYP1A1;CREB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0006338| chromatin remodeling ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP1A1;UGT1A1 GO:0032735| positive regulation of interleukin-12 production IDO1;TLR4 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;CALR GO:0050821| protein stabilization CREB1;CALR GO:0007186| G-protein coupled receptor signaling pathway MTNR1B;OPRK1;MTNR1A;OPRD1;OPRM1;CALM1 GO:0002064| epithelial cell development ESR1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;UGT1A1;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2C8;CYP1B1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;MTNR1B;CREB1;TLR4;MTNR1A;OPRK1 GO:0098869| EPX;ALB GO:0010863| positive regulation of phospholipase C activity ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;OPRM1;ESR1 GO:0030111| regulation of Wnt receptor signaling pathway ESR1 GO:0006898| receptor-mediated endocytosis ALB;CALR GO:0002376| immune system process IDO1;TLR4 GO:1903799| ESR1 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4;CYP1A2 GO:0006366| transcription from RNA polymerase II promoter ESR1;CREB1 GO:0055085| transmembrane transport ABCB1;CALM1;SLCO1A2;SLC22A8 GO:0002933| CYP3A4;CYP2C8;CYP1A1 GO:0009636| response to toxin CYP1B1;CYP1A1;SLC22A8;CES1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;CYP1A2 GO:0030879| mammary gland development CYP19A1;CREB1 GO:0006811| ion transport SLC22A8;SLCO1A2 GO:0010033| response to organic substance CYP1A2;CALR;CYP1A1;CREB1;UGT1A1 GO:0008285| negative regulation of cell proliferation OPRM1;CYP1B1 GO:0043433| negative regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0016579| protein deubiquitination ESR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;MTNR1B;MTNR1A GO:0043627| response to estrogen stimulus ESR1;OPRK1 GO:0048511| rhythmic process CREB1;RORB GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CREB1;CYP1A1 GO:0010628| positive regulation of gene expression CALR;TLR4 GO:0048146| positive regulation of fibroblast proliferation ESR1 GO:0060523| prostate epithelial cord elongation ESR1 GO:0008584| male gonad development ESR1 GO:0033146| regulation of intracellular estrogen receptor signaling pathway ESR1 GO:0043401| steroid hormone mediated signaling pathway RORB;ESR1 GO:0051000| positive regulation of nitric-oxide synthase activity ESR1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0006351| transcription, DNA-dependent ESR1;CREB1;RORB GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;OPRK1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0043124| negative regulation of I-kappaB kinase/NF-kappaB cascade ESR1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0007623| circadian rhythm MTNR1A;CREB1;MTNR1B GO:0060527| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2C19;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A1;TLR4;UGT1A1;IDO1;CYP1A2;OPRM1;MPO GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;ESR1 GO:0045899| positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ESR1;CREB1 GO:0060749| mammary gland alveolus development ESR1 GO:0042981| regulation of apoptotic process CREB1;CALR;ESR1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP1B1;CYP2C9;NQO2;CES1;CYP3A4;CYP1A2 GO:0060065| uterus development CYP19A1;ESR1 GO:0043066| negative regulation of apoptotic process MPO;ALB GO:0050727| regulation of inflammatory response TLR4;ESR1 GO:0060750| epithelial cell proliferation involved in mammary gland duct elongation ESR1 GO:0002576| platelet degranulation ALB;CALM1 GO:0043065| positive regulation of apoptotic process CREB1;IDO1;CYP1B1 GO:0030520| intracellular estrogen receptor signaling pathway ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RORB;CREB1;TLR4;ESR1 GO:0055114| oxidation-reduction process CYP19A1;CYP1A1;CYP2C9;NQO2;IDO1;CYP2C8;CYP2C19;CYP1B1;CYP3A4;EPX;CYP1A2;MPO GO:0042742| defense response to bacterium MPO;TLR4 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0030518| intracellular steroid hormone receptor signaling pathway ESR1 GO:0032094| response to food CYP1A1;MPO;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;RORB;ESR1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP2C8;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression CREB1;ESR1;OPRD1 GO:0007268| synaptic transmission OPRK1;MTNR1B;OPRM1;OPRD1 GO:0042493| response to drug UGT1A1;CALR;CYP1A1;CREB1;ABCB1;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent RORB;CALR;CREB1;ESR1 GO:0060745| mammary gland branching involved in pregnancy ESR1 GO:0071168| protein localization to chromatin ESR1 GO:0060687| regulation of branching involved in prostate gland morphogenesis ESR1 GO:0048863| stem cell differentiation ESR1 GO:0042752| regulation of circadian rhythm RORB;CREB1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter RORB;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1 GO:0001547| antral ovarian follicle growth ESR1 GO:0034121| regulation of toll-like receptor signaling pathway ESR1 GO:0006954| inflammatory response TLR4;IDO1 GO:0071391| cellular response to estrogen stimulus ESR1 GO:0060068| vagina development ESR1 11206:[DB01183 DB04830] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04830|Buformin SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLCO1A2 GO:0006811| ion transport SLC22A1;SLCO1A2 GO:0015711| organic anion transport SLC22A1;SLCO1A2 11207:[DB01183 DB06681] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06681|Belatacept CD86;CD80 common genes common pathways GO:0007165| signal transduction OPRK1;CD86;TLR4;CREB1;ESR1;OPRD1;OPRM1 GO:0002376| immune system process TLR4;CD86 GO:0006955| immune response OPRK1;CD86;TLR4;OPRD1 GO:0016032| viral reproduction CD80;CD86;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86;CREB1 11208:[DB01183 DB04664] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2B6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2B6;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2B6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C8 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8;CYP2B6 11209:[DB01183 DB04534] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04534|5-Nitroindazole NOS2;NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 GO:0001666| response to hypoxia NOS2;CREB1 GO:0007623| circadian rhythm CREB1;NOS2 GO:0032496| response to lipopolysaccharide NOS2;TLR4;UGT1A1;OPRM1 GO:0031663| lipopolysaccharide-mediated signaling pathway NOS3;TLR4 GO:0071222| cellular response to lipopolysaccharide OPRK1;NOS2;TLR4 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0009617| response to bacterium TLR4;NOS2 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0055114| oxidation-reduction process NOS3;CYP2C8;NOS2;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1;NOS2;CREB1 11210:[DB01183 DB08480] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08480|4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN MAOB common genes common pathways GO:0009636| response to toxin CES1;MAOB GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0055114| oxidation-reduction process MAOB;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;MAOB GO:0045471| response to ethanol UGT1A1;MAOB;OPRK1;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;MAOB;UGT1A1 11211:[DB01183 DB06897] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 GO:0006468| protein phosphorylation CREB1;PLK1 GO:0071168| protein localization to chromatin PLK1;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;ESR1 GO:0043066| negative regulation of apoptotic process ALB;PLK1 11212:[DB01183 DB05150] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05150|CAD106 APP common genes common pathways GO:1904646| APP;TLR4 GO:0010628| positive regulation of gene expression TLR4;APP GO:0008285| negative regulation of cell proliferation OPRM1;APP GO:1903223| APP;TLR4 GO:0007409| axonogenesis APP;CREB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;APP GO:0044267| cellular protein metabolic process ALB;APP GO:0008344| adult locomotory behavior APP;OPRD1 GO:0000187| activation of MAPK activity TLR4;APP GO:1900273| APP;CREB1 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;APP;ESR1;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway APP;OPRK1;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;APP GO:0007613| memory APP;CREB1 GO:0006468| protein phosphorylation APP;CREB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;APP;OPRM1;OPRD1 GO:0034121| regulation of toll-like receptor signaling pathway APP;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TLR4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;ESR1 GO:0008542| visual learning APP;CREB1 GO:0010629| negative regulation of gene expression APP;CREB1;OPRD1;ESR1 GO:0007268| synaptic transmission APP;OPRK1;OPRM1;OPRD1 GO:0043687| post-translational protein modification APP;ALB GO:1901215| CREB1;APP GO:0050829| defense response to Gram-negative bacterium TLR4;APP GO:0007626| locomotory behavior APP;OPRK1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;CREB1;TLR4;APP GO:0002576| platelet degranulation APP;ALB GO:0043065| positive regulation of apoptotic process APP;CREB1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0042346| positive regulation of NF-kappaB import into nucleus TLR4;APP GO:0045087| innate immune response APP;TLR4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;APP GO:1990090| CREB1;APP GO:0046330| positive regulation of JNK cascade APP;TLR4 11213:[DB01183 DB01381] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1;SLCO1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade PLA2G2A;TLR4;OPRM1 GO:0006811| ion transport GABRA1;SLCO1A2;GABRG2;GABRB2;GLRA1 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A1;CYP3A4 GO:0097267| CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0006810| transport ABCB1;GABRB2;SLC6A2;GABRA1;GABRG2 GO:0008202| steroid metabolic process CYP2C9;UGT1A1;CYP2C8;CYP3A4 GO:0050729| positive regulation of inflammatory response TLR4;PLA2G2A GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 GO:1901215| GABRB2;CREB1 GO:0007268| synaptic transmission GABRG2;OPRD1;OPRM1;SLC6A2;GLRA1;GABRB2;OPRK1 GO:0042493| response to drug ABCB1;SLC6A2;UGT1A1;CREB1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0006629| lipid metabolic process CYP2C9;PLA2G2A;CYP3A4 GO:0007218| neuropeptide signaling pathway OPRD1;OPRM1;OPRK1;GLRA1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;OPRM1 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0071294| cellular response to zinc ion CREB1;GLRA1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 11214:[DB01183 DB01208] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes ABCB1 common pathways GO:0097267| CYP2C8;CYP1A2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0015711| organic anion transport SLC22A5;SLCO1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0042908| xenobiotic transport ABCB1 GO:0006810| transport ABCB1;ABCC2 GO:0032355| response to estradiol stimulus CYP1A2;ESR1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0043627| response to estrogen stimulus ESR1;OPRK1;ABCC2 GO:0048511| rhythmic process TOP2A;CREB1 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;SLC22A5 GO:0055085| transmembrane transport SLC22A5;SLCO1A2;ABCC2;ABCB1 GO:0006811| ion transport SLC22A5;SLCO1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0033762| response to glucagon stimulus CREB1;ABCC2 GO:0043065| positive regulation of apoptotic process TOP2A;CREB1 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;ABCC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TOP2A;CREB1;TLR4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;TLR4;ABCC2;OPRM1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042752| regulation of circadian rhythm TOP2A;CREB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8 GO:0042493| response to drug CYP1A2;CREB1;UGT1A1;ABCC2;ABCB1 11215:[DB01183 DB01686] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01686|N,N-dimethylarginine NOS2;NOS3 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;CREB1;ESR1;OPRD1 GO:0055114| oxidation-reduction process CYP2C8;NOS3;NOS2;CYP3A4 GO:0042742| defense response to bacterium NOS2;TLR4 GO:0009617| response to bacterium NOS2;TLR4 GO:0032496| response to lipopolysaccharide OPRM1;TLR4;NOS2;UGT1A1 GO:0007623| circadian rhythm CREB1;NOS2 GO:0071222| cellular response to lipopolysaccharide OPRK1;TLR4;NOS2 GO:0050829| defense response to Gram-negative bacterium NOS2;TLR4 GO:0031663| lipopolysaccharide-mediated signaling pathway TLR4;NOS3 GO:0001666| response to hypoxia CREB1;NOS2 GO:0008285| negative regulation of cell proliferation OPRM1;NOS3 11216:[DB01183 DB13083] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB13083|Talarozole CYP26A1 common genes common pathways GO:0042573| retinoic acid metabolic process UGT1A1;CYP26A1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP26A1 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP26A1;CYP2C8 11217:[DB01183 DB04287] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04287|(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid PLA2G2A common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;TLR4;PLA2G2A GO:0050729| positive regulation of inflammatory response TLR4;PLA2G2A GO:0006629| lipid metabolic process CYP3A4;PLA2G2A 11218:[DB01183 DB08354] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08354|2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0048511| rhythmic process CREB1;CSNK2A1 GO:0006468| protein phosphorylation CSNK2A1;CREB1 GO:0007165| signal transduction ESR1;CSNK2A1;OPRD1;OPRM1;TLR4;CREB1;OPRK1 GO:0006355| regulation of transcription, DNA-dependent CREB1;CSNK2A1;ESR1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;CSNK2A1 11219:[DB01183 DB00403] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00403|Ceruletide CCKAR common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;OPRD1;OPRM1;CCKAR;OPRK1 GO:0007586| digestion UGT1A1;CCKAR GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;CCKAR GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;CCKAR;OPRK1 GO:0007165| signal transduction OPRD1;OPRM1;ESR1;CCKAR;TLR4;CREB1;OPRK1 GO:0032870| cellular response to hormone stimulus CCKAR;UGT1A1 GO:0007409| axonogenesis CCKAR;CREB1 GO:0007584| response to nutrient UGT1A1;CCKAR 11220:[DB01183 DB04150] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04150|Threonine Derivative PAM common genes common pathways GO:0008152| metabolic process PAM;UGT1A1;CES1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PAM GO:0007595| lactation PAM;CREB1 GO:0042493| response to drug CREB1;PAM;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process PAM;CYP2C8;CYP3A4 GO:0032355| response to estradiol stimulus PAM;ESR1 GO:0051384| response to glucocorticoid stimulus PAM;UGT1A1 GO:0001666| response to hypoxia CREB1;PAM 11221:[DB01183 DB04716] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;JAK2 GO:0030154| cell differentiation CREB1;JAK2;JAK1;TYK2 GO:0006468| protein phosphorylation JAK3;TYK2;DAPK3;CREB1;JAK2;JAK1 GO:0050729| positive regulation of inflammatory response TLR4;JAK2 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process JAK2;TLR4 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;JAK2;OPRD1;OPRM1 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;JAK2;CREB1;TLR4 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;JAK2;ESR1;OPRM1 GO:0002376| immune system process JAK3;JAK2;TLR4 GO:0008285| negative regulation of cell proliferation JAK2;OPRM1 GO:0006351| transcription, DNA-dependent CREB1;ESR1;DAPK3 GO:0097190| apoptotic signaling pathway DAPK3;TLR4 GO:0032496| response to lipopolysaccharide UGT1A1;JAK2;TLR4;OPRM1 GO:0042981| regulation of apoptotic process JAK3;ESR1;DAPK3;JAK2;CREB1 GO:0045087| innate immune response JAK2;TLR4;JAK1;JAK3;TYK2 GO:0043065| positive regulation of apoptotic process JAK2;CREB1;DAPK3 GO:0050727| regulation of inflammatory response ESR1;JAK2;TLR4 GO:0006355| regulation of transcription, DNA-dependent DAPK3;ESR1;CREB1 GO:0032760| positive regulation of tumor necrosis factor production TLR4;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;ESR1 GO:0006954| inflammatory response TLR4;JAK3 11222:[DB01183 DB06835] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 11223:[DB01183 DB01003] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways GO:0043065| positive regulation of apoptotic process KCNMA1;CREB1 GO:0006811| ion transport KCNMA1;SLCO1A2 GO:0055085| transmembrane transport SLCO1A2;KCNMA1;ABCB1 GO:0001666| response to hypoxia CREB1;KCNMA1 GO:0010033| response to organic substance UGT1A1;CREB1;S100P 11224:[DB01183 DB05311] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05311|Ecallantide KLKB1 common genes common pathways GO:0006954| inflammatory response TLR4;KLKB1 11225:[DB01183 DB11597] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 11226:[DB01183 DB07033] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways GO:0006351| transcription, DNA-dependent CREB1;PDPK1;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;PDPK1 GO:0006468| protein phosphorylation CREB1;PDPK1 11227:[DB01183 DB06902] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06902|4-(1-methyl-1-phenylethyl)phenol ESRRG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;CREB1;ESRRG GO:0045893| positive regulation of transcription, DNA-dependent ESRRG;CREB1;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESRRG GO:0043401| steroid hormone mediated signaling pathway ESRRG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;ESRRG;CREB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TLR4;CREB1;ESRRG 11228:[DB01183 DB00022] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB00022|Peginterferon alfa-2b IFNAR1;IFNAR2;CYP1A2;CYP2D6;CYP2C9 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;UGT1A1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;CYP1A2;IFNAR1;OPRM1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP2C9;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2D6;CYP2C8;CYP2C9 GO:0042493| response to drug CREB1;UGT1A1;ABCB1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C9 GO:0051607| defense response to virus OPRK1;IFNAR2 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;UGT1A1;CYP2C9;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP2D6;UGT1A1;CYP2C9;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP2C8;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CREB1;CYP1A2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 11229:[DB01183 DB03408] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03408|gamma-Glutamylcysteine GSS common genes common pathways GO:0007568| aging CREB1;GSS 11230:[DB01183 DB01830] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways GO:0006468| protein phosphorylation CREB1;LCK GO:0042493| response to drug CREB1;UGT1A1;ABCB1;LCK GO:0016032| viral reproduction LCK;CREB1 GO:0045087| innate immune response TLR4;LCK 11231:[DB01183 DB11475] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB11475|Tylosin CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 11232:[DB01183 DB08933] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8;UGT1A1 GO:0097267| CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A4 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19 11233:[DB01183 DB05465] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0006468| protein phosphorylation CREB1;FLT3 GO:0030154| cell differentiation FLT3;CREB1 GO:0036120| PDGFD;CREB1 GO:0031100| organ regeneration FLT3;UGT1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;PDGFD;TLR4 GO:0048146| positive regulation of fibroblast proliferation ESR1;PDGFD GO:0042981| regulation of apoptotic process ESR1;FLT3;CREB1 GO:0071560| cellular response to transforming growth factor beta stimulus PDGFD;CREB1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;FLT3 11234:[DB01183 DB02398] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02398|6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0001666| response to hypoxia CREB1;PLAU GO:0007165| signal transduction ESR1;OPRM1;OPRD1;PLAU;OPRK1;CREB1;TLR4 11235:[DB01183 DB02676] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways GO:0032729| positive regulation of interferon-gamma production PDE4D;TLR4 GO:0071222| cellular response to lipopolysaccharide TLR4;OPRK1;PDE4D GO:0007568| aging CREB1;PDE4D GO:0007186| G-protein coupled receptor signaling pathway OPRK1;OPRM1;PDE4D;OPRD1 GO:0007165| signal transduction TLR4;CREB1;OPRK1;OPRD1;PDE4D;OPRM1;ESR1 11236:[DB01183 DB02555] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB02555|SP4160 IL2 common genes common pathways GO:0006955| immune response OPRD1;OPRK1;IL2;TLR4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IL2;TLR4;CREB1 GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0032729| positive regulation of interferon-gamma production IL2;TLR4 GO:0045471| response to ethanol OPRK1;IL2;UGT1A1;OPRM1 GO:0030890| positive regulation of B cell proliferation IL2;TLR4 GO:0002376| immune system process TLR4;IL2 GO:0007186| G-protein coupled receptor signaling pathway IL2;OPRK1;OPRM1;OPRD1 GO:0050729| positive regulation of inflammatory response IL2;TLR4 GO:0007204| elevation of cytosolic calcium ion concentration IL2;OPRM1;ESR1 11237:[DB01183 DB08891] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;GABBR1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;GABBR1;OPRM1;OPRK1;GABBR2 GO:0007165| signal transduction GABBR1;OPRM1;OPRD1;ESR1;GABBR2;OPRK1;CREB1;TLR4 GO:0007194| negative regulation of adenylate cyclase activity GABBR2;GABBR1;OPRM1 GO:0007268| synaptic transmission OPRD1;OPRM1;OPRK1;GABBR2 11238:[DB01183 DB08618] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB08618|3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER IGHG2 common genes common pathways GO:0002376| immune system process IGHG2;TLR4 GO:0042742| defense response to bacterium IGHG2;TLR4 GO:0045087| innate immune response TLR4;IGHG2 11239:[DB01183 DB01884] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CREB1 11240:[DB01183 DB04677] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04677|N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE MAOB common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0009636| response to toxin MAOB;CES1 GO:0032496| response to lipopolysaccharide TLR4;UGT1A1;MAOB;OPRM1 GO:0045471| response to ethanol OPRM1;UGT1A1;MAOB;OPRK1 GO:0042493| response to drug UGT1A1;MAOB;CREB1;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;MAOB;CYP3A4 11241:[DB01183 DB06160] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0097267| CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0032355| response to estradiol stimulus ESR1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0010033| response to organic substance CREB1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP1A2;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;UGT1A1;TLR4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;CREB1;UGT1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C8 11242:[DB01183 DB04079] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB04079|Heptane-1,2,3-Triol RHO common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;ESR1;OPRK1;RHO;CREB1;TLR4 GO:0007186| G-protein coupled receptor signaling pathway RHO;OPRK1;OPRM1;OPRD1 GO:0006468| protein phosphorylation CREB1;RHO 11243:[DB01183 DB03881] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB03881|MT-Immucillin-H PNP common genes common pathways GO:0006955| immune response OPRD1;OPRK1;PNP;TLR4 GO:0042493| response to drug CREB1;PNP;UGT1A1;ABCB1 11244:[DB01183 DB01276] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01276|Exenatide GLP1R;ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0044267| cellular protein metabolic process ALB GO:0001895| retina homeostasis ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0051659| maintenance of mitochondrion location ALB GO:0007186| G-protein coupled receptor signaling pathway OPRM1;OPRD1;OPRK1;GLP1R GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;ESR1;OPRM1 GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0098869| ALB GO:0007165| signal transduction OPRK1;GLP1R;TLR4;CREB1;OPRD1;OPRM1;ESR1 11245:[DB01183 DB14040] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB14040|Eptinezumab CALCA;CALCB common genes common pathways GO:0050829| defense response to Gram-negative bacterium CALCA;TLR4 GO:0045087| innate immune response TLR4;CALCA GO:0007186| G-protein coupled receptor signaling pathway CALCA;OPRK1;CALCB;OPRD1;OPRM1 GO:0006468| protein phosphorylation CREB1;CALCA GO:0032757| positive regulation of interleukin-8 production CALCA;TLR4 GO:0007165| signal transduction OPRM1;OPRD1;ESR1;CREB1;TLR4;OPRK1;CALCB GO:0045671| negative regulation of osteoclast differentiation CALCA;TLR4 11246:[DB01183 DB01949] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways GO:0043065| positive regulation of apoptotic process MMP9;CREB1 GO:0043066| negative regulation of apoptotic process ALB;MMP9 11247:[DB01183 DB05217] DB01183|Naloxone OPRM1;OPRD1;OPRK1;CREB1;ESR1;TLR4;CES1;CYP2C8;CYP3A4;UGT1A1;ALB;SLCO1A2;ABCB1 DB05217|GMX1777 NAMPT common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NAMPT;TLR4;CREB1;ESR1 GO:0007623| circadian rhythm NAMPT;CREB1 GO:0007165| signal transduction ESR1;OPRM1;OPRD1;NAMPT;OPRK1;CREB1;TLR4 GO:0051770| positive regulation of nitric-oxide synthase biosynthetic process NAMPT;TLR4 GO:0048511| rhythmic process NAMPT;CREB1 GO:0014070| response to organic cyclic compound NAMPT;UGT1A1 11248:[DB00260 DB07543] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways 11249:[DB00260 DB11730] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0007623| circadian rhythm CDK4;DDC GO:0009636| response to toxin DDC;CDK4 11250:[DB00260 DB00413] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0006811| ion transport SLC22A2;SLC22A1;SLC36A2 GO:0009636| response to toxin DRD2;HTR1D;DDC GO:0035690| cellular response to drug DDC;HTR1B GO:0071312| cellular response to alkaloid DDC;HTR1B 11251:[DB00260 DB06605] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways 11252:[DB00260 DB01179] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways 11253:[DB00260 DB05127] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05127|ANA971 TLR7 common genes common pathways 11254:[DB00260 DB01148] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways 11255:[DB00260 DB01594] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0006811| ion transport GABRB3;GABRG3;GABRR3;GABRR1;GABRA1;GABRE;GABRB1;GABRG2;GABRA2;GABRB2;GABRD;SLC36A2;GABRP;GABRR2;GABRG1;GABRA3;GABRA5 GO:0009636| response to toxin GABRB1;DDC 11256:[DB00260 DB00645] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00645|Dyclonine SCN10A common genes common pathways GO:0006811| ion transport SLC36A2;SCN10A 11257:[DB00260 DB06725] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways 11258:[DB00260 DB00232] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A1 11259:[DB00260 DB01580] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport SLC22A2;SLC36A2 11260:[DB00260 DB00196] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways 11261:[DB00260 DB02789] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0006811| ion transport SLC10A6;SLC36A2 11262:[DB00260 DB08911] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways 11263:[DB00260 DB00087] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 11264:[DB00260 DB01415] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0006811| ion transport SLC15A2;SLC22A8;SLC36A2;SLC15A1 GO:0009636| response to toxin DDC;SLC22A8 GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 11265:[DB00260 DB00940] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00940|Methantheline CHRM1;HRH2 common genes common pathways 11266:[DB00260 DB00098] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways 11267:[DB00260 DB00816] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00816|Orciprenaline ADRB2 common genes common pathways 11268:[DB00260 DB00936] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLCO2B1;SLC36A2;SLC22A11;SLC22A7;SLC22A8 11269:[DB00260 DB01165] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A4;SLC22A5 11270:[DB00260 DB00671] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 GO:0006811| ion transport SLC15A1;SLC36A2;SLC22A5;SLC15A2 11271:[DB00260 DB05111] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05111|Fontolizumab IFNG common genes common pathways 11272:[DB00260 DB01023] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport CACNA1S;CACNA2D2;SLC36A2;CACNA1C;CACNA1D;CACNA1H;CACNB2;CACNA2D1 11273:[DB00260 DB01029] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0007623| circadian rhythm DDC;JUN 11274:[DB00260 DB00866] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11275:[DB00260 DB06233] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways 11276:[DB00260 DB00843] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11277:[DB00260 DB00987] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0006811| ion transport SLC22A1;SLC36A2 11278:[DB00260 DB05258] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05258|Natural alpha interferon IFNAR1 common genes common pathways 11279:[DB00260 DB14011] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0009636| response to toxin GPX1;CAT;DDC;CYP1A1;CYP1B1 GO:0006811| ion transport TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;GLRA1;TRPA1;SLC36A2;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H GO:0071363| cellular response to growth factor stimulus TRPV1;OPRD1;DDC;CAT GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0046219| indolalkylamine biosynthetic process AANAT;DDC GO:0071312| cellular response to alkaloid TRPV1;DDC GO:0007623| circadian rhythm DDC;AANAT 11280:[DB00260 DB08877] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways 11281:[DB00260 DB11641] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways 11282:[DB00260 DB00292] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0006811| ion transport GABRA1;GABRA6;GABRA4;GABRG2;GABRB1;GABRQ;GABRE;GABRG3;GABRB3;GABRP;SLC36A2;GABRD;GABRB2;GABRA5;GABRA3;GABRG1;GABRA2 GO:0009636| response to toxin GABRB1;DDC 11283:[DB00260 DB01218] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0035690| cellular response to drug KCNH2;DDC GO:0006811| ion transport SLC36A2;KCNH2 11284:[DB00260 DB01099] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01099|Flucytosine DNMT1 common genes common pathways 11285:[DB00260 DB01204] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0009636| response to toxin CYP1B1;DDC 11286:[DB00260 DB06267] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways 11287:[DB00260 DB06660] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06660|Saredutant TACR2 common genes common pathways 11288:[DB00260 DB09090] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1S 11289:[DB00260 DB12836] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways 11290:[DB00260 DB00139] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC25A10;SLC36A2;SLC13A2;SLC22A8;SLC13A3;SLC13A1 11291:[DB00260 DB00736] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00736|Esomeprazole ATP4A;CYP2C19;CYP3A4 common genes common pathways GO:0015992| proton transport ATP4A;SLC36A2 GO:0006811| ion transport SLC36A2;ATP4A 11292:[DB00260 DB01198] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0006811| ion transport GABRA2;GABRA5;GABRA3;SLC36A2;GABRA1;TSPO 11293:[DB00260 DB00854] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 11294:[DB00260 DB14050] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0071312| cellular response to alkaloid TRPV1;DDC GO:0071363| cellular response to growth factor stimulus TRPV1;DDC GO:0006811| ion transport TRPV2;TRPA1;SLC36A2;TRPV1 11295:[DB00260 DB00622] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1C;CACNA1D;SLCO1B1;CACNA2D1;CACNB2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11296:[DB00260 DB00370] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0006811| ion transport HTR3A;SLC36A2 GO:0009636| response to toxin DDC;SLC6A4;DRD2 GO:0071363| cellular response to growth factor stimulus HTR3A;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0007623| circadian rhythm SLC6A4;DDC;HTR7 11297:[DB00260 DB01118] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes common pathways GO:0006811| ion transport CACNA2D2;SLC36A2;SLC22A2;KCNH2;CACNA1H GO:0009636| response to toxin DDC;CYP1A1 GO:0035690| cellular response to drug KCNH2;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11298:[DB00260 DB00392] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0006811| ion transport GRIN3A;SLC36A2 11299:[DB00260 DB00768] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways 11300:[DB00260 DB00483] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0006811| ion transport SLC36A2;CHRNA2 11301:[DB00260 DB00300] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0035690| cellular response to drug DDC;NME1 GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC22A8;SLC36A2 11302:[DB00260 DB01036] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01036|Tolterodine CHRM3;CHRM2;CHRM5;CHRM1;CHRM4;CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11303:[DB00260 DB00960] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0035690| cellular response to drug DDC;HTR1B GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11304:[DB00260 DB14568] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC36A2;SLC22A8 11305:[DB00260 DB09273] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0035690| cellular response to drug PDE2A;DDC 11306:[DB00260 DB00290] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0009636| response to toxin BLMH;DDC 11307:[DB00260 DB14597] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14597|Lanadelumab KLKB1 common genes common pathways 11308:[DB00260 DB00945] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0006811| ion transport SLC22A7;SLC36A2 GO:0035690| cellular response to drug DDC;HSPA5;PRKAA2;TP53 11309:[DB00260 DB06739] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways 11310:[DB00260 DB00296] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0006811| ion transport SCN10A;SLC36A2 11311:[DB00260 DB01087] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1;CYP1B1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11312:[DB00260 DB11753] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways GO:0006811| ion transport SLCO1B3;SLCO1B1;SLCO1A2;SLC36A2;SLCO2B1 GO:1902600| SLC36A2;SLC47A1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11313:[DB00260 DB01124] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0006811| ion transport SLC15A1;SLC36A2;SLCO2B1;KCNJ1;SLCO1A2;SLC15A2 GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 11314:[DB00260 DB00997] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes common pathways GO:0006811| ion transport SLC22A16;SLC36A2 GO:0009636| response to toxin DDC;CYP1B1;NQO1 GO:0035690| cellular response to drug NOS2;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0071363| cellular response to growth factor stimulus NOS1;DDC GO:0007623| circadian rhythm DDC;NOS2 11315:[DB00260 DB00800] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways 11316:[DB00260 DB05676] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways GO:0035690| cellular response to drug DDC;PDE4A;PDE4B 11317:[DB00260 DB11587] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11587|Etafedrine ADRB2 common genes common pathways 11318:[DB00260 DB06469] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways 11319:[DB00260 DB06737] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways 11320:[DB00260 DB14583] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways 11321:[DB00260 DB08867] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways 11322:[DB00260 DB01251] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ8 11323:[DB00260 DB09235] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0006811| ion transport CACNA1I;SLC36A2;CACNA1C 11324:[DB00260 DB04725] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways 11325:[DB00260 DB00153] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways 11326:[DB00260 DB00358] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11327:[DB00260 DB09256] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0007623| circadian rhythm TYMS;DDC GO:0009636| response to toxin TYMS;DDC 11328:[DB00260 DB09229] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0006811| ion transport CACNA1S;SLC36A2;CACNA1F;CACNA1C;CACNA1D 11329:[DB00260 DB09078] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC22A8;SLC36A2;SLC22A2 GO:0009636| response to toxin DDC;SLC22A8 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11330:[DB00260 DB00417] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0015992| proton transport SLC36A2;SLC15A1 GO:0006811| ion transport SLC36A2;SLC15A1 11331:[DB00260 DB11691] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 11332:[DB00260 DB00738] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin DDC;CYP1A1 11333:[DB00260 DB00882] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC 11334:[DB00260 DB01248] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0006811| ion transport SLC22A7;SLCO1B3;SLC36A2 GO:0009636| response to toxin CYP1B1;BCL2;DDC 11335:[DB00260 DB00497] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 11336:[DB00260 DB08931] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC 11337:[DB00260 DB01058] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 11338:[DB00260 DB00332] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0006811| ion transport SLC22A5;SLC22A4;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11339:[DB00260 DB05025] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05025|Arimoclomol SOD1 common genes common pathways 11340:[DB00260 DB06824] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06824|Triethylenetetramine GPC1 common genes common pathways 11341:[DB00260 DB06780] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways 11342:[DB00260 DB02750] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways GO:0009636| response to toxin SLC7A8;DDC GO:0006520| cellular amino acid metabolic process SLC7A8;DDC;SLC7A5 GO:0006865| amino acid transport SLC7A5;SLC36A2;SLC7A8 11343:[DB00260 DB07374] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways 11344:[DB00260 DB00228] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0006811| ion transport GABRA2;GLRB;KCNA1;GRIA1;GABRB2;GABRD;SLC36A2;GLRA1;GABRP;KCNN4;GABRG1;GABRA3;GABRA5;GABRB3;GABRG3;ATP2C1;GABRA4;GABRA6;GABRA1;GABRE;GABRQ;GABRG2;GABRB1 GO:0009636| response to toxin GABRB1;DDC 11345:[DB00260 DB00663] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways 11346:[DB00260 DB01282] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01282|Carbetocin OXTR common genes common pathways 11347:[DB00260 DB00226] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00226|Guanadrel SLC6A2 common genes common pathways 11348:[DB00260 DB01373] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;BMP4 GO:0006811| ion transport SLC36A2;CP;ATP2C1;CACNA1C 11349:[DB00260 DB09209] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 11350:[DB00260 DB13179] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways 11351:[DB00260 DB01435] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11352:[DB00260 DB00197] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1;GSTP1 GO:0006811| ion transport SLCO1B1;SLC36A2 GO:0007623| circadian rhythm DDC;SERPINE1 11353:[DB00260 DB01186] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0035690| cellular response to drug DDC;HTR1B GO:0009636| response to toxin DDC;HTR1D;DRD2 GO:0071312| cellular response to alkaloid DDC;HTR1B 11354:[DB00260 DB00795] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00795|Sulfasalazine ALOX5;PTGS2;PTGS1;PPARG;CHUK;IKBKB;SLC7A11;ACAT1;TBXAS1;PLA2G1B;ABCG2;ABCC2;SLC46A1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0006865| amino acid transport SLC7A11;SLC36A2 GO:1902600| SLC36A2;SLC46A1 GO:0006811| ion transport SLC36A2;SLCO2B1;SLCO1B1;SLCO1B3 GO:0009636| response to toxin CHUK;DDC;SLC7A11 11355:[DB00260 DB11569] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11569|Ixekizumab IL17A common genes common pathways 11356:[DB00260 DB01032] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC36A2;SLC22A1;SLCO1C1;SLC22A2;PANX1;SLC10A1;SLC22A8;SLC22A5;SLCO1A2;SLC22A12;SLC22A7;SLC22A11 GO:1902600| SLC36A2;SLC2A9 11357:[DB00260 DB01130] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways 11358:[DB00260 DB00628] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0006811| ion transport GABRG3;GABRB3;GABRA1;GABRA6;GABRA4;TSPO;GABRG2;GABRB1;GABRQ;GABRE;GABRA2;GABRP;SLC36A2;GABRB2;GABRD;GABRA5;GABRA3;GABRG1 GO:0009636| response to toxin DDC;GABRB1 11359:[DB00260 DB09089] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0006811| ion transport CACNA1C;CACNA1D;KCNN2;CACNB4;KCNN1;KCNMB2;CACNA1H;KCNMB4;KCNMA1;CACNB2;KCNMB3;CACNA1F;CACNA1I;KCNN3;CACNB1;CACNA1S;KCNN4;CACNA1G;KCNMB1;CACNB3;SLC36A2 11360:[DB00260 DB09570] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11361:[DB00260 DB00400] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11362:[DB00260 DB01629] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01629|5-Fluorouridine SOD1 common genes common pathways 11363:[DB00260 DB00468] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 GO:0006811| ion transport SLC22A2;SLC36A2;KCNN4;SLC22A1;SLC22A5;SLCO1B1;SLC22A4;SLCO1A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11364:[DB00260 DB00208] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11365:[DB00260 DB01021] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways GO:0006811| ion transport SLC12A3;ATP1A1;SLC36A2 11366:[DB00260 DB00824] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0035690| cellular response to drug PDE4B;PDE4A;DDC 11367:[DB00260 DB11834] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11834|Guselkumab IL23A common genes common pathways 11368:[DB00260 DB08906] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 11369:[DB00260 DB02546] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0009636| response to toxin HDAC6;DDC GO:0007623| circadian rhythm HDAC3;DDC 11370:[DB00260 DB11124] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways 11371:[DB00260 DB09363] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0015842| synaptic vesicle amine transport SLC18A2;DDC GO:0009636| response to toxin MAOB;DDC;SLC18A2 11372:[DB00260 DB00912] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 11373:[DB00260 DB14010] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11374:[DB00260 DB14509] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006811| ion transport GRIA3;SLC36A2 GO:0007623| circadian rhythm DDC;GSK3B 11375:[DB00260 DB00211] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC15A1 GO:0015992| proton transport SLC36A2;SLC15A1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11376:[DB00260 DB08895] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways 11377:[DB00260 DB01324] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01324|Polythiazide SLC12A3 common genes common pathways GO:0006811| ion transport SLC12A3;SLC36A2 11378:[DB00260 DB14539] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1A2;SLC22A8 GO:0009636| response to toxin SLC22A8;DDC 11379:[DB00260 DB00863] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC22A8;SLC22A2;SLC36A2;SLC22A1 GO:0009636| response to toxin SLC22A8;DDC 11380:[DB00260 DB05885] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0006811| ion transport CACNA1B;GLRB;SLC36A2;GLRA1 11381:[DB00260 DB11127] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0009636| response to toxin DDC;GPX1 11382:[DB00260 DB09204] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11383:[DB00260 DB01205] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA2;GABRA3;GABRA5;GABRG1;GABRP;GABRD;GABRB2;SLC36A2;GABRG3;GABRB3;GABRQ;GABRG2;GABRB1;GABRE;GABRA1;GABRA6;GABRA4 11384:[DB00260 DB09185] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways 11385:[DB00260 DB00285] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways GO:0009636| response to toxin SLC6A4;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0007623| circadian rhythm DDC;SLC6A4 11386:[DB00260 DB00708] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 11387:[DB00260 DB09148] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways 11388:[DB00260 DB00390] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLCO2B1;SLCO4C1;SLCO1C1;SLC36A2;SLCO4A1;SLCO1A2;SLC22A8;SLCO1B1;ATP1A1;SLCO1B3 11389:[DB00260 DB00407] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 11390:[DB00260 DB00822] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0042423| catecholamine biosynthetic process DDC;DBH 11391:[DB00260 DB00966] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways 11392:[DB00260 DB12026] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B3;SLCO1B1 11393:[DB00260 DB00215] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin DDC;SLC6A4 GO:0007623| circadian rhythm DDC;SLC6A4 GO:0042416| dopamine biosynthetic process SLC6A3;DDC 11394:[DB00260 DB00250] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways 11395:[DB00260 DB00980] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0007623| circadian rhythm MTNR1A;MTNR1B;DDC 11396:[DB00260 DB00241] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRB3;GABRG3;CHRNA7;GRIA2;CHRNA4;GABRA4;GRIK2;GABRA6;GABRA1;GABRE;GABRB1;GABRG2;GABRQ;GABRA2;SLC36A2;GABRD;GABRB2;GABRP;GABRG1;GABRA5;GABRA3 11397:[DB00260 DB00467] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways 11398:[DB00260 DB03336] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03336|BIA COMT common genes common pathways 11399:[DB00260 DB09124] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways 11400:[DB00260 DB00013] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0007623| circadian rhythm SERPINE1;DDC 11401:[DB00260 DB01222] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways 11402:[DB00260 DB09383] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09383|Meprednisone CYP3A4;ALB common genes common pathways 11403:[DB00260 DB14009] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus TRPV1;OPRD1;DDC;CAT GO:0009636| response to toxin GPX1;CAT;DDC;CYP1A1;CYP1B1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;SLC36A2;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8 GO:0071312| cellular response to alkaloid DDC;TRPV1 GO:0007623| circadian rhythm AANAT;DDC GO:0046219| indolalkylamine biosynthetic process DDC;AANAT 11404:[DB00260 DB11338] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways 11405:[DB00260 DB00505] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways 11406:[DB00260 DB11635] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0009636| response to toxin DDC;TTPA 11407:[DB00260 DB00837] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0006811| ion transport GABRA1;SLC36A2 11408:[DB00260 DB13620] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0015992| proton transport ATP4A;SLC36A2;ATP4B GO:1902600| SLC36A2;ATP4B GO:0006811| ion transport ATP4A;SLC36A2;FXYD2;SLC12A1;ATP1A1;ATP4B 11409:[DB00260 DB00381] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin CYP1A1;DDC GO:0006811| ion transport CACNB2;CACNA2D1;CACNA1B;CACNA1D;CACNA1C;CACNA1S;SLC36A2;CACNB1;CACNA2D3 11410:[DB00260 DB01173] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0006811| ion transport GRIN3B;SCN10A;SLC36A2;GRIN3A;GRIN2D;GRIN1 11411:[DB00260 DB00915] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes DDC common pathways GO:0006520| cellular amino acid metabolic process DDC GO:0006811| ion transport CHRNA4;CHRNA7;SLC22A1;GRIN3A;SLC36A2;CHRNA3;SLC22A2 GO:0009636| response to toxin MAOB;DRD2;DDC GO:0035690| cellular response to drug DDC GO:0042427| serotonin biosynthetic process DDC GO:0015842| synaptic vesicle amine transport DDC GO:0010259| multicellular organismal aging DDC GO:0033076| isoquinoline alkaloid metabolic process DDC GO:0071363| cellular response to growth factor stimulus DDC GO:0052314| phytoalexin metabolic process DDC GO:0046219| indolalkylamine biosynthetic process DDC GO:0042416| dopamine biosynthetic process DDC GO:0019752| carboxylic acid metabolic process DDC GO:0046684| response to pyrethroid DDC GO:0007623| circadian rhythm DDC GO:0042423| catecholamine biosynthetic process DDC GO:0071312| cellular response to alkaloid DDC 11412:[DB00260 DB00214] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A1 11413:[DB00260 DB11792] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 11414:[DB00260 DB01120] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways 11415:[DB00260 DB00423] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00423|Methocarbamol CA1 common genes common pathways 11416:[DB00260 DB06726] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11417:[DB00260 DB11477] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways 11418:[DB00260 DB00244] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0009636| response to toxin DDC;CHUK 11419:[DB00260 DB11274] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0009636| response to toxin DRD2;DDC 11420:[DB00260 DB00274] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2 11421:[DB00260 DB01352] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0006811| ion transport GABRA3;GABRA5;SLC36A2;GABRA2;GRIK2;GABRA6;GABRA4;GABRA1;CHRNA4;GRIA2;CHRNA7 11422:[DB00260 DB06468] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0006811| ion transport SLC36A2;SLC9A1 GO:1902600| SLC9A1;SLC36A2 11423:[DB00260 DB01044] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways 11424:[DB00260 DB00759] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways GO:0006811| ion transport SLC22A11;SLC22A7;SLC22A8;SLCO2B1;SLC36A2 GO:0035690| cellular response to drug DDC;PRNP GO:0009636| response to toxin DDC;SLC22A8 11425:[DB00260 DB04894] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways 11426:[DB00260 DB01206] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11427:[DB00260 DB12001] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0007623| circadian rhythm CDK4;DDC GO:0006520| cellular amino acid metabolic process DDC;OTC GO:0009636| response to toxin CDK4;DDC GO:1902600| SLC47A1;SLC36A2 11428:[DB00260 DB01131] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11429:[DB00260 DB00421] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;SRD5A1 GO:0006811| ion transport SLC36A2;CACNA2D2;CACNB3;CACNA1G;CACNA1S;CACNB1;CACNA2D3;CACNA1A;CACNA1I;CACNA1F;CACNA2D1;CACNB2;CACNA1B;CACNA1H;SLCO1A2;CACNG1;CACNA1D;CACNB4;CACNA1C 11430:[DB00260 DB00415] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0006811| ion transport SLC15A2;SLC22A5;SLC36A2;SLC15A1 GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 11431:[DB00260 DB00312] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA2;GRIN3B;GABRP;GABRD;GABRB2;GRIN3A;SLC36A2;GABRA3;GABRA5;GRIN2C;GABRG1;GRIN2A;CHRNA7;GABRG3;GABRB3;GRIA2;CHRNA4;GABRA1;GRIN2B;GABRA6;GRIK2;GABRA4;GABRQ;GABRB1;GABRG2;GRIN2D;GRIN1;GABRE 11432:[DB00260 DB00650] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A8 GO:0009636| response to toxin SLC22A8;DDC 11433:[DB00260 DB09183] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11434:[DB00260 DB00111] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 11435:[DB00260 DB01030] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0007623| circadian rhythm DDC;TOP1 GO:1902600| SLC36A2;SLC47A1 11436:[DB00260 DB01466] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11437:[DB00260 DB00568] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin DRD2;CYP1A1;DDC GO:0006811| ion transport CACNA1H;CACNA1D;CACNA1C;SLC36A2;CACNA1S;CACNA1G;CACNA1I;CACNA1F 11438:[DB00260 DB01053] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC15A1;SLC36A2;SLCO2B1;SLC22A4;SLCO3A1;SLC22A8;SLC22A5;SLC15A2;SLCO1B1;SLC22A11;SLCO4A1 11439:[DB00260 DB03907] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways 11440:[DB00260 DB01085] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways 11441:[DB00260 DB00227] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin PON3;DDC GO:0006811| ion transport SLCO1A2;SLCO1B1;SLC36A2 11442:[DB00260 DB01645] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes common pathways GO:0071363| cellular response to growth factor stimulus AKT1;DDC GO:0006811| ion transport SLCO1B1;SLCO2B1;SLC36A2 GO:0009636| response to toxin CYP1B1;DDC GO:0007623| circadian rhythm NCOA2;DDC 11443:[DB00260 DB00883] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways 11444:[DB00260 DB01033] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A8 GO:0009636| response to toxin DDC;SLC22A8 GO:0035690| cellular response to drug DDC;PPAT GO:0007623| circadian rhythm DDC;IMPDH2 11445:[DB00260 DB06372] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways GO:0035690| cellular response to drug IL1B;DDC 11446:[DB00260 DB08814] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0007623| circadian rhythm DDC;NOS2 GO:0035690| cellular response to drug NOS2;DDC 11447:[DB00260 DB00365] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes common pathways GO:0006811| ion transport SLC22A5;SLC22A2;SLC36A2 11448:[DB00260 DB11619] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways 11449:[DB00260 DB09272] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC GO:0006811| ion transport SLC36A2;SLCO1B1;SLC22A8 GO:0009636| response to toxin SLC22A8;DDC 11450:[DB00260 DB00294] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways 11451:[DB00260 DB00657] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0006811| ion transport CHRNA7;CHRNA4;CHRNA2;SLC36A2;CHRNB2 11452:[DB00260 DB01182] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0035690| cellular response to drug KCNH2;DDC GO:0006811| ion transport SCN5A;KCNH2;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11453:[DB00260 DB01104] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01104|Sertraline SLC6A4;SLC6A3;PGRMC1;SIGMAR1;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP2B6;MAOB;MAOA;CYP2B;ALB;ABCB1 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0007623| circadian rhythm DDC;SLC6A4 GO:0009636| response to toxin DDC;SLC6A4;MAOB GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11454:[DB00260 DB00810] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0006811| ion transport SLC36A2;CHRNA2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11455:[DB00260 DB01018] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways 11456:[DB00260 DB05361] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05361|SR-123781A SERPINC1;F2R common genes common pathways 11457:[DB00260 DB01409] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0006811| ion transport SLC22A4;SLC22A5;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11458:[DB00260 DB00812] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006811| ion transport SLC22A11;SLC22A8;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8 11459:[DB00260 DB00865] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0015842| synaptic vesicle amine transport DDC;SLC18A2 GO:0009636| response to toxin SLC18A2;DDC GO:0042416| dopamine biosynthetic process DDC;SLC6A3 11460:[DB00260 DB13941] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways 11461:[DB00260 DB00764] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways 11462:[DB00260 DB00694] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0009636| response to toxin DDC;CYP1B1;CYP1A1 11463:[DB00260 DB00189] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRG3;GABRB3;GABRA1;GABRA4;GABRA6;GABRQ;GABRG2;GABRB1;GABRE;GABRA2;GABRP;GABRD;GABRB2;SLC36A2;GABRA3;GABRA5;GABRG1 11464:[DB00260 DB01366] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01366|Procaterol ADRB2 common genes common pathways 11465:[DB00260 DB01656] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways GO:0035690| cellular response to drug PDE4A;DDC;PDE4B 11466:[DB00260 DB01440] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006811| ion transport GABRB1;SLC36A2 GO:0009636| response to toxin DDC;GABRB1 11467:[DB00260 DB08874] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways 11468:[DB00260 DB13036] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13036|Ramatroban PTGDR2 common genes common pathways 11469:[DB00260 DB01144] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 11470:[DB00260 DB00033] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 11471:[DB00260 DB00857] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11472:[DB00260 DB04829] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11473:[DB00260 DB13997] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways 11474:[DB00260 DB01083] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways 11475:[DB00260 DB00691] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC36A2;SLC15A1;SLC15A2 GO:0006811| ion transport SLC15A2;SLC36A2;SLC15A1 11476:[DB00260 DB09060] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0006811| ion transport SLC22A8;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8 11477:[DB00260 DB00434] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0007623| circadian rhythm HTR7;DDC 11478:[DB00260 DB00949] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0006811| ion transport GRIN2A;GRIN2B;GRIN3A;SLC36A2 11479:[DB00260 DB08912] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B3;SLCO1B1;SLC22A8 GO:0035690| cellular response to drug DDC;BRAF GO:0009636| response to toxin SLC22A8;DDC 11480:[DB00260 DB09258] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways 11481:[DB00260 DB05936] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05936|CVT-6883 ADORA2B common genes common pathways 11482:[DB00260 DB00347] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1G 11483:[DB00260 DB11755] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0006811| ion transport TRPM8;SLC36A2;TRPA1;TRPV2 11484:[DB00260 DB00378] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways 11485:[DB00260 DB01005] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11486:[DB00260 DB08918] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin SLC6A4;DDC GO:0007623| circadian rhythm SLC6A4;DDC 11487:[DB00260 DB13168] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways 11488:[DB00260 DB03066] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 11489:[DB00260 DB00787] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways GO:1902600| SLC47A1;SLC36A2 GO:0006811| ion transport SLC22A8;SLC22A1;SLC36A2;SLC10A2 GO:0009636| response to toxin SLC22A8;DDC 11490:[DB00260 DB01170] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways 11491:[DB00260 DB00029] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm DDC;SERPINE1 11492:[DB00260 DB03023] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0009636| response to toxin LYN;DDC 11493:[DB00260 DB00550] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 GO:0042423| catecholamine biosynthetic process DBH;DDC 11494:[DB00260 DB06419] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways 11495:[DB00260 DB09052] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09052|Blinatumomab CD19;CD3D common genes common pathways 11496:[DB00260 DB01129] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0006811| ion transport ATP4A;SLC36A2 GO:0009636| response to toxin CYP1A1;DDC GO:0015992| proton transport ATP4A;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11497:[DB00260 DB06589] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin PDGFRB;DDC GO:0006811| ion transport SLC36A2;SLCO1B1 11498:[DB00260 DB00698] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways 11499:[DB00260 DB01261] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways GO:0006811| ion transport SLC22A8;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8 11500:[DB00260 DB08892] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways 11501:[DB00260 DB00830] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC 11502:[DB00260 DB01708] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRQ;GABRG2;GABRB1;GRIN2D;GRIN1;GABRE;GABRA1;GRIN2B;GABRA6;GABRA4;GRIN2A;GABRG3;GABRB3;GABRA3;GABRA5;GRIN2C;GABRG1;GABRP;GABRB2;GABRD;GRIN3A;SLC36A2;GRIN3B;GABRA2 11503:[DB00260 DB01108] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways 11504:[DB00260 DB04861] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11505:[DB00260 DB09198] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes common pathways GO:0006811| ion transport SLCO3A1;SLCO1B1;SLC36A2 11506:[DB00260 DB06733] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways GO:0006811| ion transport SLC36A2;ATP6V1A GO:0015992| proton transport SLC36A2;ATP6V1A 11507:[DB00260 DB02056] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways 11508:[DB00260 DB04821] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0015842| synaptic vesicle amine transport DDC;SLC18A2 GO:0009636| response to toxin MAOB;DDC;SLC6A4;SLC18A2 GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0007623| circadian rhythm DDC;SLC6A4 11509:[DB00260 DB00193] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;DDC GO:0006811| ion transport CHRNA7;GRIN3A;SLC36A2 GO:0009636| response to toxin DDC;SLC6A4 GO:0071363| cellular response to growth factor stimulus OPRD1;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11510:[DB00260 DB01022] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 11511:[DB00260 DB04576] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways 11512:[DB00260 DB02337] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 11513:[DB00260 DB00611] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 11514:[DB00260 DB02105] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02105|3,5-Dinitrocatechol COMT common genes common pathways 11515:[DB00260 DB00745] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC 11516:[DB00260 DB06770] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11517:[DB00260 DB01234] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0007623| circadian rhythm NOS2;DDC GO:0009636| response to toxin CYP1B1;CYP1A1;DDC GO:0035690| cellular response to drug DDC;NOS2 GO:0006811| ion transport SLC36A2;SLCO1A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11518:[DB00260 DB00779] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways 11519:[DB00260 DB01016] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes common pathways GO:0007623| circadian rhythm CPT1A;DDC GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 GO:0006811| ion transport SLC22A7;KCNJ11;KCNJ5;SLC15A2;SLCO1A2;KCNJ8;SLCO2B1;SLC36A2;SLC15A1;CFTR 11520:[DB00260 DB05928] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLCO1B3;SLC36A2;SLCO2B1 GO:0009636| response to toxin CYP1A1;DDC 11521:[DB00260 DB13952] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2;SLC22A3;SLC22A11;SLCO4A1;MT-ATP6;CHRNA4;SLC36A2;SLC22A1;SLCO1C1;SLCO2B1;SLC22A2 GO:0015992| proton transport MT-ATP6;SLC36A2 GO:0007623| circadian rhythm NCOA2;DDC 11522:[DB00260 DB06704] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06704|Iobenguane SLC6A2 common genes common pathways 11523:[DB00260 DB00142] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0019752| carboxylic acid metabolic process DDC;GAD2;GAD1 GO:0010259| multicellular organismal aging DDC;SLC1A2 GO:1902600| SLC36A2;SLC25A18;SLC25A22 GO:0006811| ion transport GRID1;GRIN3A;SLC36A2;SLC1A7;SLC25A18;SLC25A22;GRID2;GRIA4;GRIN2C;GRIK3;GRIK5;SLC1A1;SLC1A2;SLC1A3;GRIN3B;GRIK4;GRIA1;GRIN2B;GRIK2;GRIA3;GRIN1;GRIN2D;GRIN2A;GRIA2;SLC1A6;GRIK1 GO:0006520| cellular amino acid metabolic process TAT;GLS2;GOT2;DDC;GOT1;GLUD2;ASNS;GLUD1 GO:0009636| response to toxin ASNS;SLC7A11;DDC GO:0006865| amino acid transport SLC1A6;SLC7A11;SLC16A10;SLC1A3;SLC1A2;SLC1A1;SLC36A2 11524:[DB00260 DB00439] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLCO1B1;SLC36A2 11525:[DB00260 DB00593] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1G 11526:[DB00260 DB06594] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0007623| circadian rhythm DDC;MTNR1A;MTNR1B 11527:[DB00260 DB00486] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways 11528:[DB00260 DB05120] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05120|AT1391 INSR common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;INSR 11529:[DB00260 DB00198] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8;CES1 GO:0006811| ion transport SLC36A2;SLC15A1;SLC22A8 GO:0015992| proton transport SLC36A2;SLC15A1 11530:[DB00260 DB00188] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11531:[DB00260 DB08871] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0009636| response to toxin DDC;BCL2 11532:[DB00260 DB00304] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways 11533:[DB00260 DB09285] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways 11534:[DB00260 DB01210] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11535:[DB00260 DB06217] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0035690| cellular response to drug DDC;KCNH2 GO:0006811| ion transport KCND3;SCN5A;KCNH2;KCNA5;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11536:[DB00260 DB02266] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways 11537:[DB00260 DB02377] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0042416| dopamine biosynthetic process DDC;GCH1 11538:[DB00260 DB01174] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01174|Phenobarbital GABRA1;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP2C19;CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2;CYP2A6;CYP2E1;CYP3A5;CYP4A11;CYP1A1;CYP1B1;CYP2C18;CYP3A7;CYP4B1;UGT1A1;UGT2B7;ABCB1;ABCC3;ABCB11;ABCC1;SLCO2A1;ABCC2 common genes common pathways GO:0009636| response to toxin CYP1A1;CYP1B1;DDC GO:0006811| ion transport GRIN2C;SLC36A2;GRIN3A;GRIN3B;GRIN2D;GRIN1;GABRA1;GRIK2;GRIN2B;CHRNA4;GRIA2;CHRNA7;GRIN2A 11539:[DB00260 DB11251] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;TTPA 11540:[DB00260 DB00973] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 11541:[DB00260 DB01577] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0007623| circadian rhythm DDC;SLC6A4 GO:0009636| response to toxin MAOB;SLC18A2;SLC6A4;DDC GO:0006811| ion transport SLC36A2;SLC22A5;SLC22A3 GO:0015842| synaptic vesicle amine transport SLC18A1;SLC18A2;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11542:[DB00260 DB09330] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0007623| circadian rhythm DDC;EGFR GO:0035690| cellular response to drug DDC;EGFR GO:0071363| cellular response to growth factor stimulus DDC;EGFR 11543:[DB00260 DB05740] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0006811| ion transport CHRNA7;CHRNA2;CHRNA4;CHRNA9;SLC36A2;CHRNB2;CHRNA10 11544:[DB00260 DB00451] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00451|Levothyroxine THRA;THRB;CYP2C8;UGT1A1;TTR;SERPINA7;ALB;SLCO1C1;SLC16A2;ABCB1;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4A1;SLCO4C1;SLC7A5;SLCO2B1 common genes common pathways GO:0006865| amino acid transport SLC36A2;SLC7A5 GO:0006811| ion transport SLCO2B1;SLCO4C1;SLCO1C1;SLC36A2;SLCO4A1;SLCO1A2;SLCO1B1;SLCO1B3 GO:0006520| cellular amino acid metabolic process SLC7A5;DDC 11545:[DB00260 DB06362] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 11546:[DB00260 DB00473] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways GO:0006811| ion transport SLC36A2;SCN10A;SCN5A 11547:[DB00260 DB00441] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0009636| response to toxin DDC;TYMS GO:0007623| circadian rhythm TYMS;DDC 11548:[DB00260 DB00235] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00235|Milrinone PDE3A common genes common pathways 11549:[DB00260 DB05015] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0007623| circadian rhythm HDAC3;DDC GO:0009636| response to toxin HDAC6;DDC 11550:[DB00260 DB01396] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways GO:0006811| ion transport SLCO1A2;ATP1A1;SLC36A2;SLCO4C1 11551:[DB00260 DB06717] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways 11552:[DB00260 DB03619] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0009636| response to toxin DDC;GSTP1 GO:0006811| ion transport SLCO1A2;SLC36A2;SLC10A1;SLC10A2 11553:[DB00260 DB00404] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport GABRA2;SLC36A2;GABRB2;GABRD;GABRP;GABRG1;GABRA5;GABRA3;GABRB3;GABRG3;GABRA4;GABRA6;GABRA1;GABRE;GABRB1;GABRG2;GABRQ 11554:[DB00260 DB01407] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC 11555:[DB00260 DB01439] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 11556:[DB00260 DB00072] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0007623| circadian rhythm EGFR;DDC GO:0071363| cellular response to growth factor stimulus ERBB2;DDC;EGFR GO:0035690| cellular response to drug EGFR;DDC 11557:[DB00260 DB00959] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways 11558:[DB00260 DB01411] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways 11559:[DB00260 DB00041] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways 11560:[DB00260 DB09555] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC22A2;SLC36A2;SLC22A1 11561:[DB00260 DB01429] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0006811| ion transport SCN5A;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11562:[DB00260 DB09338] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways 11563:[DB00260 DB00379] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;SCN5A GO:0009636| response to toxin DDC;AHR GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11564:[DB00260 DB09418] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways GO:0006811| ion transport SLC5A5;SLC36A2 11565:[DB00260 DB00526] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0035690| cellular response to drug DDC;MT2A GO:0009636| response to toxin CYP1A1;NQO1;CYP1B1;GSTP1;DDC GO:0006811| ion transport SLC22A3;SLC22A2;ATP7A;SLC31A1;ATP7B;SLC36A2 11566:[DB00260 DB01127] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways 11567:[DB00260 DB00380] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways 11568:[DB00260 DB00195] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11569:[DB00260 DB09288] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes common pathways GO:0006811| ion transport SLC36A2;TRPV1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus TRPV1;DDC GO:0071312| cellular response to alkaloid TRPV1;DDC 11570:[DB00260 DB01363] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0007623| circadian rhythm DDC;SLC6A4 GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0015842| synaptic vesicle amine transport DDC;SLC18A2;SLC18A1 GO:0009636| response to toxin SLC6A4;DDC;SLC18A2;MAOB 11571:[DB00260 DB00499] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0009636| response to toxin DDC;CYP1B1;CYP1A1;AHR 11572:[DB00260 DB14540] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1A2;SLC22A8 GO:0009636| response to toxin DDC;SLC22A8 11573:[DB00260 DB13953] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0015992| proton transport MT-ATP6;SLC36A2 GO:0009636| response to toxin CYP1B1;CYP1A1;DDC;SLC22A8 GO:0006811| ion transport SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2;SLC22A3;SLC22A11;SLCO4A1;MT-ATP6;CHRNA4;SLC36A2;SLC22A1;SLCO1C1;SLCO2B1;SLC22A2 GO:0007623| circadian rhythm NCOA2;DDC 11574:[DB00260 DB09291] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11575:[DB00260 DB01351] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0006811| ion transport GABRA2;SLC36A2;GABRA3;GABRA5;CHRNA7;GRIA2;CHRNA4;GABRA1;GABRA4;GABRA6;GRIK2 11576:[DB00260 DB01380] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways 11577:[DB00260 DB00435] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways 11578:[DB00260 DB13872] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0006811| ion transport GABRA1;GABRG2;GABRA2;SLC36A2;GABRA3;GABRA5 11579:[DB00260 DB06787] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 11580:[DB00260 DB06652] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways 11581:[DB00260 DB06412] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;SRD5A1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11582:[DB00260 DB00604] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;HTR3A GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;HTR3A;KCNH2 GO:0035690| cellular response to drug KCNH2;DDC 11583:[DB00260 DB08901] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0009636| response to toxin DDC;LYN GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11584:[DB00260 DB11581] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0009636| response to toxin DDC;BCL2 GO:0006811| ion transport SLCO1B1;SLC36A2 11585:[DB00260 DB01138] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0006811| ion transport SLC22A12;SLC36A2 11586:[DB00260 DB06713] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways 11587:[DB00260 DB00637] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;KCNH2;KCNH1 GO:0035690| cellular response to drug KCNH2;DDC 11588:[DB00260 DB01252] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways 11589:[DB00260 DB00814] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways 11590:[DB00260 DB06262] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes DDC common pathways GO:0046684| response to pyrethroid DDC GO:0007623| circadian rhythm DDC GO:0019752| carboxylic acid metabolic process DDC GO:0071312| cellular response to alkaloid DDC GO:0042423| catecholamine biosynthetic process DDC;PAH GO:0046219| indolalkylamine biosynthetic process DDC GO:0042416| dopamine biosynthetic process DDC GO:0071363| cellular response to growth factor stimulus DDC GO:0033076| isoquinoline alkaloid metabolic process DDC GO:0006865| amino acid transport SLC36A2;SLC16A10 GO:0052314| phytoalexin metabolic process DDC GO:0006520| cellular amino acid metabolic process DDC GO:0035690| cellular response to drug DDC GO:0009636| response to toxin DDC GO:0010259| multicellular organismal aging DDC GO:0042427| serotonin biosynthetic process DDC GO:0015842| synaptic vesicle amine transport DDC 11591:[DB00260 DB01254] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0071363| cellular response to growth factor stimulus FYN;STAT5B;DDC GO:0009636| response to toxin DDC;CYP1B1;PDGFRB;CYP1A1;LYN GO:0035690| cellular response to drug DDC;PPAT 11592:[DB00260 DB01059] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC GO:0006811| ion transport SLC22A5;SLC36A2 11593:[DB00260 DB05303] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways 11594:[DB00260 DB00002] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0035690| cellular response to drug EGFR;DDC GO:0071363| cellular response to growth factor stimulus EGFR;DDC GO:0007623| circadian rhythm DDC;EGFR 11595:[DB00260 DB02701] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0019752| carboxylic acid metabolic process DDC;LDHA 11596:[DB00260 DB00338] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;CYP1B1;AHR;CYP1A1 GO:0006811| ion transport ATP4A;SLC36A2 GO:0015992| proton transport SLC36A2;ATP4A GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11597:[DB00260 DB09146] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09146|Iron saccharate HBA1;TF common genes common pathways GO:0006811| ion transport SLC36A2;TF 11598:[DB00260 DB00533] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways 11599:[DB00260 DB00083] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 11600:[DB00260 DB06772] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLCO1B3;SLCO1B1;SLC36A2 11601:[DB00260 DB01395] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways 11602:[DB00260 DB01126] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0071363| cellular response to growth factor stimulus SRD5A1;DDC 11603:[DB00260 DB06370] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11604:[DB00260 DB11348] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0071363| cellular response to growth factor stimulus CIB1;DDC;SPARC GO:0006811| ion transport CACNB1;RYR2;CACNA1F;SLC34A2;CACNA1A;CACNA1I;CACNB3;TRPV6;SLC36A2;RYR3;CACNA1E;PKD2L1;CACNA1G;TRPV5;CATSPER1;CACNA1S;SLC20A2;PKD1L3;RYR1;SLC34A1;CACNA1C;SLC8A1;CACNA1D;CACNB4;SLC34A3;SLC20A1;CACNB2;CACNA1H 11605:[DB00260 DB09389] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;SRD5A1 11606:[DB00260 DB12191] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12191|Obatoclax BCL2 common genes common pathways GO:0009636| response to toxin BCL2;DDC 11607:[DB00260 DB08807] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0035690| cellular response to drug HTR1B;DDC 11608:[DB00260 DB11130] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 11609:[DB00260 DB06734] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways GO:0015992| proton transport SLC36A2;ATP6V1A GO:0006811| ion transport ATP6V1A;SLC36A2 11610:[DB00260 DB00589] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0009636| response to toxin HTR1D;DDC;DRD2 GO:0035690| cellular response to drug DDC;HTR1B GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0007623| circadian rhythm DDC;HTR7 11611:[DB00260 DB09502] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:1902600| SLC36A2;SLC2A10;SLC2A8;SLC2A9;SLC2A12;SLC2A6 11612:[DB00260 DB01200] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0071312| cellular response to alkaloid HTR1B;DDC GO:0007623| circadian rhythm HTR7;DDC GO:0009636| response to toxin HTR1D;DDC;DRD2 GO:0035690| cellular response to drug HTR1B;DDC 11613:[DB00260 DB01240] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways 11614:[DB00260 DB05039] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways 11615:[DB00260 DB04825] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways 11616:[DB00260 DB09029] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09029|Secukinumab IL17A common genes common pathways 11617:[DB00260 DB00836] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1A GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 11618:[DB00260 DB12332] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:1902600| SLC36A2;SLC47A1 GO:0006811| ion transport SLC22A1;SLC36A2;SLCO1B3;SLCO1B1;SLC22A8 GO:0009636| response to toxin DDC;SLC22A8 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11619:[DB00260 DB02998] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0007623| circadian rhythm DDC;NCOA2 11620:[DB00260 DB14635] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0009636| response to toxin GSTP1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11621:[DB00260 DB00877] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 GO:1902600| SLC36A2;SLC47A1 11622:[DB00260 DB11712] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0006811| ion transport SLC36A2;CFTR 11623:[DB00260 DB07462] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways 11624:[DB00260 DB06212] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways 11625:[DB00260 DB05668] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05668|Palifosfamide DNMT1 common genes common pathways 11626:[DB00260 DB03403] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 11627:[DB00260 DB00685] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways 11628:[DB00260 DB06237] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways 11629:[DB00260 DB01102] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways 11630:[DB00260 DB11703] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 11631:[DB00260 DB00655] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC22A8;SLCO1A2;SLCO2B1;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8;CYP1B1;CYP1A1 11632:[DB00260 DB00696] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0071312| cellular response to alkaloid HTR1B;DDC GO:0009636| response to toxin DRD2;HTR1D;DDC GO:0035690| cellular response to drug HTR1B;DDC 11633:[DB00260 DB05087] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0006811| ion transport GABRA1;GABRA6;GABRA4;SLC36A2;GABRA5;GABRA3;GABRA2 11634:[DB00260 DB04840] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin DDC;CYP1A1 11635:[DB00260 DB00886] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00886|Omapatrilat ACE;MME common genes common pathways 11636:[DB00260 DB14642] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways 11637:[DB00260 DB01219] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways GO:0006811| ion transport RYR1;SLC36A2 11638:[DB00260 DB00845] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways 11639:[DB00260 DB09166] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0006811| ion transport SLC36A2;GABRA3;GABRA2;GABRA1;GABRG2 11640:[DB00260 DB00782] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00782|Propantheline CHRM1 common genes common pathways 11641:[DB00260 DB14508] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007623| circadian rhythm DDC;GSK3B GO:0006811| ion transport GRIA3;SLC36A2 11642:[DB00260 DB01008] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways GO:0009636| response to toxin GSTP1;DDC 11643:[DB00260 DB06211] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0035690| cellular response to drug DPEP1;DDC GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC36A2;SLC22A8 11644:[DB00260 DB00517] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways 11645:[DB00260 DB08838] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0006811| ion transport SLC22A3;GRIN1;CACNA1B;ASIC3;KCNJ1;SLC22A2;SLC22A1;SLC36A2;CHRNA1 GO:0006520| cellular amino acid metabolic process DDC;SLC7A7 GO:0006865| amino acid transport SLC36A2;SLC7A7 11646:[DB00260 DB00131] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0007623| circadian rhythm DDC;CREB1;ADCY1 GO:0071363| cellular response to growth factor stimulus CREB1;DDC GO:0035690| cellular response to drug DDC;FBP1;PDE4B 11647:[DB00260 DB00594] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:1902600| SLC9A1;SLC36A2 GO:0006811| ion transport SLC36A2;ASIC2;SLC22A2;SCNN1D;ASIC1;SCNN1B;SLC22A4;SCNN1A;SLC9A1;SCNN1G 11648:[DB00260 DB00569] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways 11649:[DB00260 DB11358] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways 11650:[DB00260 DB09282] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 11651:[DB00260 DB00630] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0015992| proton transport ATP6V1A;SLC36A2 GO:0006811| ion transport ATP6V1A;SLC36A2 11652:[DB00260 DB00237] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA2;GABRP;GABRB2;GABRD;SLC36A2;GABRA3;GABRA5;GABRG1;GABRG3;CHRNA7;GABRB3;CHRNA4;GRIA2;GABRA1;GABRA4;GABRA6;GRIK2;GABRQ;GABRB1;GABRG2;GABRE 11653:[DB00260 DB11094] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways 11654:[DB00260 DB01080] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0015808| L-alanine transport SLC36A1;SLC36A2 GO:0035524| proline transmembrane transport SLC36A2;SLC36A1 GO:0006865| amino acid transport SLC36A1;SLC36A2 GO:0015992| proton transport SLC36A2;SLC36A1 GO:0015824| proline transport SLC36A2;SLC36A1 GO:1902600| SLC36A1;SLC36A2 GO:0006811| ion transport SLC36A1;SLC36A2 GO:0015816| glycine transport SLC36A1;SLC36A2 11655:[DB00260 DB09053] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11656:[DB00260 DB00276] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0006811| ion transport SLC36A2;KCNH2 GO:0035690| cellular response to drug KCNH2;DDC 11657:[DB00260 DB00346] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0006811| ion transport KCNH2;SLC36A2 GO:0035690| cellular response to drug DDC;KCNH2 11658:[DB00260 DB09265] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09265|Lixisenatide GLP1R common genes common pathways 11659:[DB00260 DB11586] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLCO1B3;SLCO2B1;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11660:[DB00260 DB00675] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin DDC;CES1;CYP1B1;CYP1A1 GO:0035690| cellular response to drug KCNH2;DDC GO:0006811| ion transport SLC36A2;KCNH2 11661:[DB00260 DB14065] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways 11662:[DB00260 DB01019] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways 11663:[DB00260 DB08613] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways 11664:[DB00260 DB01496] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0006811| ion transport GRIK2;GABRA6;GABRA4;GABRA1;GRIA2;CHRNA4;CHRNA7;GABRA3;GABRA5;SLC36A2;GABRA2 11665:[DB00260 DB04948] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:1902600| SLC47A1;SLC36A2 GO:0009636| response to toxin DDC;HTR1D GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0007623| circadian rhythm HTR7;DDC 11666:[DB00260 DB11637] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways 11667:[DB00260 DB00414] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ1 11668:[DB00260 DB00494] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11669:[DB00260 DB01548] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 11670:[DB00260 DB06148] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0007623| circadian rhythm HTR7;DDC;SLC6A4 GO:0009636| response to toxin SLC6A4;DDC;DRD2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11671:[DB00260 DB00315] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin HTR1D;DDC 11672:[DB00260 DB07720] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0006811| ion transport CHRNA7;CHRNA4;CHRNA2;CHRFAM7A;CHRNA3;SLC36A2;CHRNB4;CHRNB2 11673:[DB00260 DB03566] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0006811| ion transport SLC22A4;SLC22A1;SLC36A2 11674:[DB00260 DB01074] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport KCNH2;SLC36A2 GO:0035690| cellular response to drug KCNH2;DDC GO:0007623| circadian rhythm CPT1A;DDC 11675:[DB00260 DB05091] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05091|M0002 AVPR2 common genes common pathways 11676:[DB00260 DB06595] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin DDC;PDGFRB 11677:[DB00260 DB00790] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 GO:0006811| ion transport SLC15A2;SLC36A2;SLC15A1 11678:[DB00260 DB01296] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways 11679:[DB00260 DB12866] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0006811| ion transport SLC22A8;SLC36A2 GO:0009636| response to toxin SLC22A8;DDC 11680:[DB00260 DB00849] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0006811| ion transport GABRA2;SLC36A2;GABRA3;GABRA5;CHRNA7;GRIA2;CHRNA4;GABRA4;GABRA6;GRIK2;GABRA1 11681:[DB00260 DB01412] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0035690| cellular response to drug DDC;PDE4B 11682:[DB00260 DB04827] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways 11683:[DB00260 DB00521] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11684:[DB00260 DB00549] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways 11685:[DB00260 DB06700] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0009636| response to toxin DDC;SLC6A4 GO:0007623| circadian rhythm DDC;SLC6A4 11686:[DB00260 DB00852] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin FOS;SLC6A4;DDC GO:0006520| cellular amino acid metabolic process ATF4;DDC GO:0007623| circadian rhythm JUN;ATF4;SLC6A4;DDC;ATF5 GO:0042416| dopamine biosynthetic process DDC;SLC6A3 11687:[DB00260 DB05022] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05022|Amonafide TOP2A;TOP2B common genes common pathways 11688:[DB00260 DB00534] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A1 11689:[DB00260 DB01588] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRP;SLC36A2;GABRB2;GABRD;GABRA5;GABRA3;GABRG1;GABRR2;GABRA2;GABRA1;GABRR1;GABRA6;GABRA4;GABRB1;GABRG2;GABRQ;GABRE;GABRG3;GABRB3;GABRR3 11690:[DB00260 DB00396] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin DDC;CYP1B1;CYP1A1 GO:0006811| ion transport SLC22A3;SLCO1B1;SLC10A1;SLC22A2;SLC22A1;SLC36A2 11691:[DB00260 DB00289] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0006811| ion transport GRIN2A;GRIN2B;GRIN2D;GRIN1;GRIN3B;SLC36A2;GRIN3A;GRIN2C GO:0009636| response to toxin SLC6A4;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0007623| circadian rhythm DDC;SLC6A4 11692:[DB00260 DB06751] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1C GO:0035690| cellular response to drug DDC;PDE4A 11693:[DB00260 DB04926] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04926|Neramexane GRIN3A common genes common pathways GO:0006811| ion transport SLC36A2;GRIN3A 11694:[DB00260 DB01650] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0006811| ion transport SLC22A8;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8 11695:[DB00260 DB05521] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC36A2;SLCO2B1 11696:[DB00260 DB01257] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01257|Eculizumab C5 common genes common pathways 11697:[DB00260 DB00150] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes DDC common pathways GO:0019752| carboxylic acid metabolic process DDC GO:0046684| response to pyrethroid DDC GO:0007623| circadian rhythm TPH1;TPH2;DDC GO:0071312| cellular response to alkaloid DDC GO:0042423| catecholamine biosynthetic process DDC GO:0042416| dopamine biosynthetic process DDC GO:0046219| indolalkylamine biosynthetic process TPH2;TPH1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC GO:0071363| cellular response to growth factor stimulus DDC GO:0052314| phytoalexin metabolic process DDC GO:0006865| amino acid transport SLC16A10;SLC36A2 GO:0035690| cellular response to drug DDC GO:0009636| response to toxin DDC GO:0006520| cellular amino acid metabolic process DDC GO:0042427| serotonin biosynthetic process DDC;TPH1;TPH2 GO:0015842| synaptic vesicle amine transport DDC GO:0010259| multicellular organismal aging DDC 11698:[DB00260 DB01288] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways 11699:[DB00260 DB08827] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways 11700:[DB00260 DB06155] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways 11701:[DB00260 DB06274] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 11702:[DB00260 DB11431] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways 11703:[DB00260 DB06292] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC5A2 GO:0009636| response to toxin DDC;CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11704:[DB00260 DB00715] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin SLC6A4;DDC 11705:[DB00260 DB05688] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0009636| response to toxin SLC6A4;DDC GO:0007623| circadian rhythm SLC6A4;DDC 11706:[DB00260 DB00567] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways GO:1902600| SLC36A2;SLC47A1 GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC15A1;SLC36A2;SLC22A8;SLC22A5;SLC15A2 GO:0015992| proton transport SLC36A2;SLC15A1;SLC15A2 11707:[DB00260 DB01483] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0006811| ion transport CHRNA7;CHRNA4;GRIA2;GABRA4;GABRA6;GRIK2;GABRA1;GABRA2;SLC36A2;GABRA3;GABRA5 11708:[DB00260 DB00834] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11709:[DB00260 DB01551] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11710:[DB00260 DB00978] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A5 11711:[DB00260 DB06603] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0007623| circadian rhythm DDC;HDAC3 GO:0009636| response to toxin HDAC6;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11712:[DB00260 DB09030] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways 11713:[DB00260 DB06342] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways 11714:[DB00260 DB00537] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0035690| cellular response to drug DDC;KCNH2 GO:0006811| ion transport KCNH2;SLC36A2 GO:1902600| SLC36A2;SLC47A1 11715:[DB00260 DB00713] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2 11716:[DB00260 DB00305] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00305|Mitomycin POR common genes common pathways 11717:[DB00260 DB01047] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways 11718:[DB00260 DB00501] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00501|Cimetidine HRH2;CYP1A2;CYP2C19;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP11B1;CYP2C8;CYP2C9;CYP2E1;FMO3;FMO1;ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A6;SLC22A8;SLC47A1;SLC22A4;SLC22A11;SLC22A7;ABCB11;SLC47A2 common genes common pathways GO:0006811| ion transport SLC22A8;SLC22A5;SLC22A3;SLC22A4;SLC22A7;SLC22A11;SLC36A2;SLC22A1;SLC22A2 GO:0009636| response to toxin SLC22A8;DDC GO:1902600| SLC47A1;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11719:[DB00260 DB00619] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0007623| circadian rhythm NTRK1;DDC GO:0071363| cellular response to growth factor stimulus DDC;NTRK1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin PDGFRB;DDC GO:0006811| ion transport SLC36A2;SLC22A1;SLC22A2 11720:[DB00260 DB01263] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways 11721:[DB00260 DB08882] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways 11722:[DB00260 DB00182] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0015842| synaptic vesicle amine transport SLC18A2;DDC GO:0009636| response to toxin DRD2;MAOB;SLC6A4;DDC;SLC18A2 GO:0006811| ion transport SLC36A2;SLC22A5;SLC22A3 GO:0007623| circadian rhythm DDC;SLC6A4 GO:0042416| dopamine biosynthetic process DDC;SLC6A3 11723:[DB00260 DB00921] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 11724:[DB00260 DB01590] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1;SLCO1B3;SLCO1A2 11725:[DB00260 DB00661] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0009636| response to toxin DDC;SLC6A4 GO:0035690| cellular response to drug KCNH2;DDC GO:0006811| ion transport CACNA1C;CACNA1D;CACNB4;SCN5A;SLC22A4;SLCO1A2;KCNH2;CACNA1B;SLC22A5;SLCO1B1;KCNJ11;CACNB2;CACNA1F;CACNA1I;CACNA1A;CACNB1;SLC22A1;CACNA1S;CACNA1G;CACNB3;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0007623| circadian rhythm SLC6A4;DDC 11726:[DB00260 DB01307] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;INSR 11727:[DB00260 DB01571] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 11728:[DB00260 DB00353] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways 11729:[DB00260 DB08820] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0006811| ion transport CFTR;SLC36A2 11730:[DB00260 DB00324] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways 11731:[DB00260 DB04938] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11732:[DB00260 DB13961] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0006811| ion transport CACNA1F;CACNB1;CACNA1S;SLC36A2;CACNB3;CACNA1D;CACNB4;CACNA1C;CACNB2 GO:0007623| circadian rhythm DDC;SREBF1 11733:[DB00260 DB00261] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways 11734:[DB00260 DB01098] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways GO:0009636| response to toxin DDC;SLC7A11;SLC22A8 GO:0006811| ion transport SLC36A2;SLCO2B1;SLC22A8;SLCO1B1;SLCO1B3;SLCO1A2 GO:0006865| amino acid transport SLC36A2;SLC7A11 11735:[DB00260 DB01236] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:0006811| ion transport GABRA2;GRIA1;KCNA1;SLC36A2;GABRB2;GABRD;GABRP;GLRA1;GABRG1;GABRA5;GABRA3;GABRB3;GABRG3;ATP2C1;GABRA6;GABRA4;GABRA1;GABRE;GABRG2;GABRB1;GABRQ GO:0009636| response to toxin GABRB1;DDC 11736:[DB00260 DB09481] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0009636| response to toxin TRPM6;DDC GO:0006811| ion transport GRIN2C;SLC36A2;GRIN3A;GRIN3B;GRIN1;TRPM7;GRIN2D;CNNM2;GRIN2B;TRPM6;GRIN2A 11737:[DB00260 DB13954] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006811| ion transport CHRNA4;MT-ATP6;SLCO4A1;SLC22A11;SLC22A3;SLCO1A2;SLCO1B3;SLCO1B1;SLC22A8;SLCO2B1;SLC22A2;SLC22A1;SLCO1C1;SLC36A2 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;DDC GO:0015992| proton transport SLC36A2;MT-ATP6 GO:0007623| circadian rhythm NCOA2;DDC 11738:[DB00260 DB00075] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 11739:[DB00260 DB09063] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways 11740:[DB00260 DB00607] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways 11741:[DB00260 DB05932] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways 11742:[DB00260 DB00514] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;DDC GO:0071363| cellular response to growth factor stimulus OPRD1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin SLC6A4;DDC GO:0006811| ion transport CHRNA2;CHRNA4;CHRNA7;CHRNB2;CYBB;CHRNB4;GRIN3A;SLC36A2;CHRNA3 11743:[DB00260 DB01101] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways GO:0007623| circadian rhythm DDC;TYMS GO:0009636| response to toxin TYMS;CES1;DDC 11744:[DB00260 DB13141] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 11745:[DB00260 DB13867] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC36A2 11746:[DB00260 DB01275] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways 11747:[DB00260 DB01327] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0009636| response to toxin PON1;SLC22A8;DDC GO:0006811| ion transport SLC36A2;SLC22A8;SLC22A11 11748:[DB00260 DB07280] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 11749:[DB00260 DB00342] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0035690| cellular response to drug DDC;KCNH2 GO:0006811| ion transport SLC36A2;KCNH2 11750:[DB00260 DB00398] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC36A2 GO:0009636| response to toxin PDGFRB;DDC GO:0035690| cellular response to drug BRAF;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11751:[DB00260 DB09034] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways 11752:[DB00260 DB00470] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 11753:[DB00260 DB01336] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways GO:0006811| ion transport CHRNA2;SLC36A2 11754:[DB00260 DB06655] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways 11755:[DB00260 DB00559] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways 11756:[DB00260 DB00823] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways 11757:[DB00260 DB01154] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ8;GABRA1;KCNJ11 11758:[DB00260 DB06779] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways 11759:[DB00260 DB05501] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways 11760:[DB00260 DB06702] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11761:[DB00260 DB00462] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways 11762:[DB00260 DB00351] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways 11763:[DB00260 DB11672] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin DDC;GSTP1 11764:[DB00260 DB00668] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0009636| response to toxin MAOB;DDC GO:0006811| ion transport SLC22A1;SLC36A2;SLC22A2 11765:[DB00260 DB09295] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0006811| ion transport CLCNKA;SLC36A2 11766:[DB00260 DB00328] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLC10A1;SLC22A8;SLCO1B1;SLCO1A2;SLC22A7;SLC22A11 GO:0009636| response to toxin CES1;SLC22A8;DDC 11767:[DB00260 DB00394] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways 11768:[DB00260 DB00286] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC22A11;SLCO4A1;SLCO3A1;SLCO1A2;SLC22A8;SLCO1B1;SLCO1B3;SLC10A1;SLCO2B1;SLCO1C1;SLC36A2 11769:[DB00260 DB00811] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0007623| circadian rhythm IMPDH2;DDC 11770:[DB00260 DB00577] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways GO:0009636| response to toxin DDC;SLC6A14;SLC22A8 GO:0006811| ion transport SLC22A8;SLC15A2;SLC10A2;SLC36A2;SLC15A1 GO:0006520| cellular amino acid metabolic process DDC;SLC6A14 GO:0006865| amino acid transport SLC6A14;SLC36A2 GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 11771:[DB00260 DB01397] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways 11772:[DB00260 DB01149] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport SLCO1B3;KCNH2;SLCO2B1;SLC36A2 GO:0035690| cellular response to drug KCNH2;DDC GO:0009636| response to toxin SLC6A4;DDC GO:0007623| circadian rhythm DDC;SLC6A4 GO:0042416| dopamine biosynthetic process SLC6A3;DDC 11773:[DB00260 DB11582] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA2;GABRG1;GABRA3;GABRA5;GABRB2;GABRD;SLC36A2;GLRA1;GABRP;GABRB3;GABRG3;GABRE;GABRQ;GABRG2;GABRB1;GABRA6;GABRA4;GABRA1 11774:[DB00260 DB00982] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00982|Isotretinoin RARA common genes common pathways 11775:[DB00260 DB00202] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0006811| ion transport CHRNA7;SLC36A2;CHRNA10 11776:[DB00260 DB13178] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13178|Inositol SLC5A3 common genes common pathways GO:0006811| ion transport SLC5A3;SLC36A2 11777:[DB00260 DB01364] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0015842| synaptic vesicle amine transport DDC;SLC18A2 GO:0009636| response to toxin DDC;SLC18A2 11778:[DB00260 DB06697] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11779:[DB00260 DB01095] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0015992| proton transport SLC15A1;SLC36A2 GO:0009636| response to toxin CYP1A1;DDC GO:0006811| ion transport SLCO1B1;SLCO1B3;SLC15A1;SLC36A2;SLCO2B1 11780:[DB00260 DB14063] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways 11781:[DB00260 DB04953] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways GO:0006811| ion transport SLC36A2;KCNQ4;KCNQ2;KCNQ5;KCNQ3 11782:[DB00260 DB06707] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways 11783:[DB00260 DB00320] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0009636| response to toxin HTR1D;DDC GO:0035690| cellular response to drug HTR1B;DDC GO:0071312| cellular response to alkaloid HTR1B;DDC 11784:[DB00260 DB01213] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;CAT GO:0009636| response to toxin DDC;CAT 11785:[DB00260 DB00368] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0006811| ion transport SLC22A3;SLC22A5;SLC22A1;SLC36A2;SLC22A2 GO:0009636| response to toxin SLC18A2;DDC GO:0015842| synaptic vesicle amine transport DDC;SLC18A1;SLC18A2 GO:0042423| catecholamine biosynthetic process PAH;DDC 11786:[DB00260 DB00074] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways 11787:[DB00260 DB00755] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 11788:[DB00260 DB00749] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways 11789:[DB00260 DB03128] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A1;CHRNA7;SLC22A5 11790:[DB00260 DB01306] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01306|Insulin Aspart INSR common genes common pathways GO:0071363| cellular response to growth factor stimulus INSR;DDC 11791:[DB00260 DB05773] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0071363| cellular response to growth factor stimulus ERBB2;DDC 11792:[DB00260 DB00148] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0006811| ion transport SLC6A8;SLC22A5;SLC36A2 11793:[DB00260 DB13151] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0007623| circadian rhythm DDC;F7 11794:[DB00260 DB00475] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006811| ion transport GABRG3;GABRB3;GABRA1;GABRA6;GABRA4;GABRG2;GABRB1;GABRQ;GABRE;GABRA2;GABRP;SLC36A2;GABRD;GABRB2;GABRA5;GABRA3;GABRG1 GO:0009636| response to toxin DDC;GABRB1 11795:[DB00260 DB01431] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways 11796:[DB00260 DB01610] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways GO:0006520| cellular amino acid metabolic process DDC;SLC6A14 GO:0006811| ion transport SLC36A2;SLC15A1;SLC15A2 GO:0009636| response to toxin SLC6A14;DDC GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 GO:0006865| amino acid transport SLC6A14;SLC36A2 11797:[DB00260 DB01382] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ1 11798:[DB00260 DB08836] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0015992| proton transport SLC15A1;SLC36A2 GO:0006811| ion transport SLCO1A2;SLC15A1;SLC36A2 11799:[DB00260 DB00714] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0035690| cellular response to drug DDC;HTR1B GO:0009636| response to toxin DRD2;DDC;HTR1D GO:0071312| cellular response to alkaloid DDC;HTR1B 11800:[DB00260 DB09099] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways 11801:[DB00260 DB00176] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes common pathways GO:0007623| circadian rhythm SLC6A4;DDC GO:0009636| response to toxin DDC;SLC6A4;CYP1A1 GO:0035690| cellular response to drug DDC;KCNH2 GO:0006811| ion transport KCNH2;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11802:[DB00260 DB06822] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways 11803:[DB00260 DB00200] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0006811| ion transport SLC36A2;TCN1;TCN2 11804:[DB00260 DB09564] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09564|Insulin Degludec INSR common genes common pathways GO:0071363| cellular response to growth factor stimulus INSR;DDC 11805:[DB00260 DB14517] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0006811| ion transport SLC36A2;TF;ATP1A1 11806:[DB00260 DB01212] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006811| ion transport SLC15A1;SLC36A2;SLC22A11;SLC22A8;SLC15A2 GO:0009636| response to toxin SLC22A8;DDC GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 11807:[DB00260 DB00762] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes common pathways GO:0009636| response to toxin DDC;CES1 GO:0006811| ion transport SLC22A3;SLCO1B1;SLC36A2 GO:0007623| circadian rhythm TOP1;DDC 11808:[DB00260 DB00243] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SCN5A;SCN9A;SLC36A2 GO:0009636| response to toxin SCN9A;DDC 11809:[DB00260 DB00884] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00884|Risedronate FDPS;PTGS2 common genes common pathways 11810:[DB00260 DB01014] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways 11811:[DB00260 DB00993] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways 11812:[DB00260 DB01056] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0006811| ion transport SLC36A2;SCN5A 11813:[DB00260 DB00555] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0009636| response to toxin GABRB1;DDC;DRD2 GO:0006811| ion transport GABRB3;GABRG3;GABRA6;GABRA4;GABRA1;GABRE;GABRG2;GABRB1;GABRQ;SCN2A;GABRA2;SLC22A2;HTR3A;SLC36A2;GABRD;GABRB2;GABRP;GABRG1;CACNA1E;GABRA5;GABRA3 GO:0071363| cellular response to growth factor stimulus DDC;HTR3A 11814:[DB00260 DB11077] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways 11815:[DB00260 DB04896] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0009636| response to toxin DDC;SLC6A4 GO:0006811| ion transport GRIN3A;SLC36A2;GRIN2C;GRIN3B;GRIN2B;GRIN1;GRIN2D;GRIN2A GO:0007623| circadian rhythm DDC;SLC6A4 11816:[DB00260 DB01354] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0006811| ion transport GRIA2;CHRNA4;CHRNA7;GABRA1;GABRA4;GABRA6;GRIK2;GABRA2;GABRA3;GABRA5;SLC36A2 11817:[DB00260 DB01255] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0006811| ion transport SLC15A1;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0015992| proton transport SLC15A1;SLC36A2 11818:[DB00260 DB01253] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01253|Ergometrine ADRA1A;CYP3A4;ABCB1 common genes common pathways 11819:[DB00260 DB01202] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways GO:0006811| ion transport CACNA1B;SLC36A2 11820:[DB00260 DB00007] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways 11821:[DB00260 DB00301] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways 11822:[DB00260 DB00255] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00255|Diethylstilbestrol ESR1;ESRRG;ESR2;ESRRA;ESRRB;NCOA2;NR1I2;AR;SHBG;COMT;CYP19A1;CYP3A4;CYP2C8;CYP2C9;CYP2E1;TTR;ABCG2;ABCB1;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0007623| circadian rhythm NCOA2;DDC GO:0006811| ion transport SLCO1B1;SLC36A2;SLCO2B1 11823:[DB00260 DB00455] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport KCNH2;SLC36A2 GO:0035690| cellular response to drug DDC;KCNH2 11824:[DB00260 DB00893] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0006811| ion transport TF;SLC36A2 11825:[DB00260 DB13874] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLCO1B3;SLCO1B1;SLC22A8;SLC36A2;SLC22A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11826:[DB00260 DB01136] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ4;KCNH2 GO:0009636| response to toxin DDC;CYP1A1 GO:0035690| cellular response to drug DDC;KCNH2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11827:[DB00260 DB00425] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0006811| ion transport GABRB3;GABRA1;GABRG2;GABRA2;SLC36A2;GABRA3 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11828:[DB00260 DB11278] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways 11829:[DB00260 DB03542] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 11830:[DB00260 DB11979] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;SLCO1B1 11831:[DB00260 DB07776] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0009636| response to toxin CYP1B1;DDC 11832:[DB00260 DB00962] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0006811| ion transport SLC36A2;GABRA1;TSPO 11833:[DB00260 DB09328] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways 11834:[DB00260 DB01026] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1A2;KCNH2;SLCO1B1 GO:0035690| cellular response to drug DDC;KCNH2 GO:0009636| response to toxin DDC;CYP1B1;CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11835:[DB00260 DB00784] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00784|Mefenamic acid PTGS2;PTGS1;CYP2C9;CYP2C8;UGT1A9;ALB common genes common pathways 11836:[DB00260 DB01203] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11837:[DB00260 DB04911] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11838:[DB00260 DB06228] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06228|Rivaroxaban F10;CYP3A4;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways 11839:[DB00260 DB11090] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways GO:0006811| ion transport SLC36A2;KCNH2 GO:0035690| cellular response to drug DDC;KCNH2 11840:[DB00260 DB01097] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0009636| response to toxin AHR;DDC 11841:[DB00260 DB00670] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00670|Pirenzepine CHRM1 common genes common pathways 11842:[DB00260 DB01169] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0009636| response to toxin CYP1B1;CDKN1A;MAPK1;CYP1A1;DDC;MAPK3 GO:0071363| cellular response to growth factor stimulus AKT1;DDC GO:0007623| circadian rhythm JUN;DDC 11843:[DB00260 DB04878] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04878|Voglibose MGAM common genes common pathways 11844:[DB00260 DB00311] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways 11845:[DB00260 DB00308] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0035690| cellular response to drug DDC;KCNH2 GO:0006811| ion transport KCNH6;CACNB1;KCNH7;KCNK1;SLC36A2;KCNK6;CACNA1C;CACNG1;KCNH2;CACNA2D1;KCNJ11 11846:[DB00260 DB09237] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0035690| cellular response to drug NOS2;DDC GO:0006811| ion transport CACNA1C;SLC36A2 GO:0007623| circadian rhythm NOS2;DDC 11847:[DB00260 DB00570] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0007623| circadian rhythm DDC;JUN GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;SLCO1B1 11848:[DB00260 DB04348] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0006865| amino acid transport SLC7A11;SLC36A2 GO:0009636| response to toxin DDC;SLC7A11;SLC22A8 GO:0006811| ion transport SLC36A2;SLCO1C1;SLCO2B1;SLC10A1;SLC10A2;SLCO1B3;SLC22A8;SLCO1B1;SLCO1A2;SLCO3A1;SLCO4A1 11849:[DB00260 DB00463] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006811| ion transport GABRB2;GABRD;SLC36A2;GABRP;GABRG1;GABRA3;GABRA5;GABRA2;GRIK2;GABRA6;GABRA4;GABRA1;GABRE;GABRQ;GABRG2;GABRB1;GABRB3;CHRNA7;GABRG3;CHRNA4;GRIA2 GO:0009636| response to toxin DDC;GABRB1 11850:[DB00260 DB00579] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0009636| response to toxin DDC;SLC6A4;SLC18A2 GO:0015842| synaptic vesicle amine transport SLC18A2;DDC GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0007623| circadian rhythm DDC;SLC6A4 11851:[DB00260 DB04895] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04895|Pegaptanib NRP1 common genes common pathways 11852:[DB00260 DB00678] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A12 GO:1902600| SLC36A2;SLC2A9 11853:[DB00260 DB14538] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLCO1A2;SLC22A8;SLC36A2 11854:[DB00260 DB01384] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways 11855:[DB00260 DB06712] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0006811| ion transport CACNA2D3;SLC36A2;CACNA1S;CACNA1D;CACNA1C;CACNA2D1;CACNB2 11856:[DB00260 DB00627] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0006811| ion transport SLCO2B1;SLC5A8;SLC36A2;SLC22A5 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11857:[DB00260 DB00401] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0006811| ion transport CACNA2D1;CACNB2;CACNA1C;CACNA1D;CACNA1S;SLC36A2 11858:[DB00260 DB01054] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways GO:0006811| ion transport CACNA2D1;CACNB2;CACNA1H;CACNG1;CACNA1C;CACNA1D;CACNA2D2;SLC36A2;CACNA1S 11859:[DB00260 DB04100] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways 11860:[DB00260 DB00126] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0042423| catecholamine biosynthetic process DDC;DBH GO:0006811| ion transport SLC23A1;SLC36A2 GO:0009636| response to toxin DDC;SLC23A1 11861:[DB00260 DB01274] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11862:[DB00260 DB09413] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09413|Monopotassium phosphate ALPI common genes common pathways 11863:[DB00260 DB02745] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 11864:[DB00260 DB00669] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1;SLCO1A2 GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin HTR1D;DDC GO:0071312| cellular response to alkaloid DDC;HTR1B 11865:[DB00260 DB03506] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03506|9-Deazaadenine APRT common genes common pathways 11866:[DB00260 DB06636] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways 11867:[DB00260 DB00081] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 11868:[DB00260 DB08049] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways 11869:[DB00260 DB11198] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways 11870:[DB00260 DB00490] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0009636| response to toxin DRD2;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11871:[DB00260 DB01043] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0071363| cellular response to growth factor stimulus HTR3A;DDC GO:0006811| ion transport SLC22A2;HTR3A;SLC36A2;GRIN3A;CHRNA7;GRIN2A;GRIN2B;GRIN1 GO:0009636| response to toxin DRD2;DDC 11872:[DB00260 DB00968] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes DDC common pathways GO:0007623| circadian rhythm DDC GO:0046684| response to pyrethroid DDC GO:0019752| carboxylic acid metabolic process DDC GO:0042423| catecholamine biosynthetic process DDC GO:0071312| cellular response to alkaloid DDC GO:0042416| dopamine biosynthetic process DDC GO:0046219| indolalkylamine biosynthetic process DDC GO:0071363| cellular response to growth factor stimulus DDC GO:0033076| isoquinoline alkaloid metabolic process DDC GO:0015992| proton transport SLC36A2;SLC15A1 GO:0052314| phytoalexin metabolic process DDC GO:0009636| response to toxin DDC GO:0035690| cellular response to drug DDC GO:0006811| ion transport SLC36A2;SLC15A1 GO:0006520| cellular amino acid metabolic process DDC GO:0010259| multicellular organismal aging DDC GO:0015842| synaptic vesicle amine transport DDC GO:0042427| serotonin biosynthetic process DDC 11873:[DB00260 DB01107] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006811| ion transport GABRP;GABRD;GABRB2;SLC36A2;GABRA3;GABRA5;GABRG1;GABRA2;GABRA1;GABRA6;GABRA4;GABRQ;GABRB1;GABRG2;GABRE;GABRG3;GABRB3 GO:0009636| response to toxin DDC;GABRB1 11874:[DB00260 DB01076] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3 GO:0009636| response to toxin DDC;AHR GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11875:[DB00260 DB09073] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0007623| circadian rhythm DDC;CDK4 GO:0009636| response to toxin CDK4;DDC 11876:[DB00260 DB08816] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11877:[DB00260 DB00424] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 11878:[DB00260 DB09045] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09045|Dulaglutide GLP1R common genes common pathways 11879:[DB00260 DB00706] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00706|Tamsulosin ADRA1A;ADRA1D;ADRA1B;CYP3A4;CYP2D6;ORM1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11880:[DB00260 DB06307] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06307|Apoptone BCL2 common genes common pathways GO:0009636| response to toxin DDC;BCL2 11881:[DB00260 DB00356] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0006811| ion transport SLC36A2;KCNMA1 GO:0009636| response to toxin DDC;CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11882:[DB00260 DB09039] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11883:[DB00260 DB01332] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways GO:0015992| proton transport SLC15A1;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC36A2;SLC15A1;SLC22A8 11884:[DB00260 DB00322] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0009636| response to toxin DDC;TYMS GO:0007623| circadian rhythm DDC;TYMS 11885:[DB00260 DB03664] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03664|UP5 CMPK1 common genes common pathways 11886:[DB00260 DB01216] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0071363| cellular response to growth factor stimulus SRD5A1;DDC 11887:[DB00260 DB06650] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06650|Ofatumumab MS4A1 common genes common pathways 11888:[DB00260 DB00371] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0006811| ion transport GABRB3;GABRG3;GABRE;GABRG2;GABRB1;GABRQ;GABRA4;GABRA6;GABRA1;GABRA2;GABRG1;GABRA5;GABRA3;SLC36A2;GABRB2;GABRD;GABRP GO:0009636| response to toxin GABRB1;DDC 11889:[DB00260 DB06684] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0009636| response to toxin SLC6A4;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0007623| circadian rhythm SLC6A4;DDC 11890:[DB00260 DB00530] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0009636| response to toxin CYP1B1;CYP1A1;DDC GO:0035690| cellular response to drug EGFR;DDC GO:0006811| ion transport SLCO2B1;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus DDC;EGFR GO:0007623| circadian rhythm DDC;EGFR 11891:[DB00260 DB00903] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0009636| response to toxin GSTP1;DDC GO:0006811| ion transport SLC12A1;ATP1A1;SLC36A2 11892:[DB00260 DB01223] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways 11893:[DB00260 DB00108] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0071312| cellular response to alkaloid ICAM1;DDC 11894:[DB00260 DB09236] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways GO:0006811| ion transport CACNB2;CACNB4;CACNA1D;CACNA1C;CACNA1S;SLC36A2;CACNB3;CACNA1F;CACNB1 11895:[DB00260 DB09070] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways 11896:[DB00260 DB04905] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11897:[DB00260 DB00487] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways 11898:[DB00260 DB11397] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0006811| ion transport SLC36A2;TF 11899:[DB00260 DB01589] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA6;GABRR1;GABRA4;GABRA1;GABRE;GABRQ;GABRB1;GABRG2;GABRB3;GABRG3;GABRR3;GABRB2;GABRD;SLC36A2;GABRP;GABRR2;GABRG1;GABRA3;GABRA5;GABRA2 11900:[DB00260 DB00104] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways 11901:[DB00260 DB01064] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0009636| response to toxin DDC;MAPK1;CYP1A1 11902:[DB00260 DB09280] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways GO:0006811| ion transport CFTR;SLC36A2 11903:[DB00260 DB00633] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11904:[DB00260 DB01587] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport SLC36A2;GABRD;GABRG1;GABRA1;TSPO;GABRB1;GABRE 11905:[DB00260 DB09154] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways GO:0006811| ion transport SLC13A5;SLC36A2;SLC13A2 11906:[DB00260 DB01231] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways 11907:[DB00260 DB00710] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00710|Ibandronate FDPS common genes common pathways 11908:[DB00260 DB01583] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0006865| amino acid transport SLC36A2;SLC16A10 GO:0006811| ion transport SLCO4A1;SLCO1A2;SLCO1B1;SLC22A8;SLCO1B3;SLC10A1;SLCO4C1;SLCO1C1;SLC36A2 GO:0009636| response to toxin SLC22A8;DDC 11909:[DB00260 DB00331] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:1902600| SLC36A2;SLC47A1 GO:0006811| ion transport SLC22A2;SLC22A1;SLC36A2;SLC22A3 11910:[DB00260 DB09230] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;CACNB1 11911:[DB00260 DB04957] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0006811| ion transport KCNQ1;SLC36A2;KCNE1;KCNH2 GO:0035690| cellular response to drug DDC;KCNH2;KCNQ1 GO:0009636| response to toxin CYP1A1;DDC 11912:[DB00260 DB05514] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05514|Cobiprostone CLCN2 common genes common pathways GO:0006811| ion transport CLCN2;SLC36A2 11913:[DB00260 DB01559] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport GABRA1;GABRR1;GABRB1;GABRG2;GABRE;GABRG3;GABRB3;GABRR3;GABRP;GABRD;GABRB2;SLC36A2;GABRA3;GABRA5;GABRR2;GABRG1;GABRA2 11914:[DB00260 DB04794] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways 11915:[DB00260 DB12141] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:1902600| SLC36A2;SLC47A1 GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin DDC;HTR1D GO:0006811| ion transport HTR3A;HTR3E;SLC22A1;SLC36A2;HTR3D;HTR3B;HTR3C GO:0071363| cellular response to growth factor stimulus DDC;HTR3A GO:0071312| cellular response to alkaloid HTR1B;DDC GO:0007623| circadian rhythm DDC;HTR7 11916:[DB00260 DB00769] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways 11917:[DB00260 DB00252] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes common pathways GO:0006811| ion transport SCN5A;SCN1A;SCN3A;SLC36A2;SCN1B;SLCO1C1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0046684| response to pyrethroid SCN1B;DDC 11918:[DB00260 DB00078] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 11919:[DB00260 DB11614] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11920:[DB00260 DB14064] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways 11921:[DB00260 DB06814] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06814|Protokylol ADRB2 common genes common pathways 11922:[DB00260 DB00773] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes common pathways GO:0009636| response to toxin DDC;GSTP1 11923:[DB00260 DB00580] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways 11924:[DB00260 DB00515] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes common pathways GO:0006811| ion transport SLC22A2;ATOX1;ATP7A;SLC31A2;ATP7B;SLC31A1;SLC36A2;TF GO:0035690| cellular response to drug DDC;MT2A GO:0009636| response to toxin DDC;NQO1;GSTP1 11925:[DB00260 DB00794] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0006811| ion transport GABRB2;GABRD;SLC36A2;GABRP;GABRG1;GABRA3;GABRA5;GABRA2;GRIK2;GABRA6;GABRA4;GABRA1;GABRE;GABRQ;GABRB1;GABRG2;GABRB3;CHRNA7;GABRG3;CHRNA4;GRIA2 GO:0009636| response to toxin DDC;GABRB1 11926:[DB00260 DB00178] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC36A2;SLC15A1;SLC15A2 GO:0006811| ion transport SLC15A2;SLC15A1;SLC36A2 11927:[DB00260 DB09227] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1C 11928:[DB00260 DB00925] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0006811| ion transport SLC22A3;SLC36A2;SLC22A1;SLC22A2 11929:[DB00260 DB12418] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12418|Saccharin CA3 common genes common pathways 11930:[DB00260 DB00446] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways 11931:[DB00260 DB01973] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 11932:[DB00260 DB00373] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11933:[DB00260 DB02508] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways 11934:[DB00260 DB00393] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0006811| ion transport CACNB2;CACNA1C;CACNA1D;CACNB4;CACNB3;SLC36A2;CACNA1S;CACNB1;CACNA1F GO:0009636| response to toxin AHR;DDC 11935:[DB00260 DB00716] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways 11936:[DB00260 DB00825] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0006811| ion transport TRPA1;CACNB3;SLC36A2;CACNA1S;TRPM8;CACNB1;CACNA1F;CACNB2;TRPV3;CACNA1C;CACNB4;CACNA1D 11937:[DB00260 DB01105] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0009636| response to toxin SLC6A4;DDC GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0007623| circadian rhythm SLC6A4;DDC 11938:[DB00260 DB00207] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways 11939:[DB00260 DB01128] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11940:[DB00260 DB06290] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes common pathways GO:0006811| ion transport SLCO1B3;SLCO1B1;SLC10A1;SLCO2B1;SLC36A2 11941:[DB00260 DB06287] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11942:[DB00260 DB11995] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0006811| ion transport SLC22A8;SLC36A2 GO:0009636| response to toxin SLC22A8;DDC 11943:[DB00260 DB06457] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06457|Tecastemizole KCNH2 common genes common pathways GO:0006811| ion transport KCNH2;SLC36A2 GO:0035690| cellular response to drug DDC;KCNH2 11944:[DB00260 DB07117] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 11945:[DB00260 DB00829] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00829|Diazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9;CYP2B6;CYP2C18;CYP2C8;PTGS1;CYP2E1;ALB;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport GABRA2;GABRP;GABRB2;GABRD;SLC36A2;GABRA3;GABRA5;GABRR2;GABRG1;GABRG3;GABRB3;GABRR3;GABRA1;TSPO;GABRA6;GABRR1;GABRA4;GABRQ;GABRG2;GABRB1;GABRE 11946:[DB00260 DB00864] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00864|Tacrolimus FKBP1A;CYP3A7;CYP3A5;CYP3A4;ALB;ORM1;ABCB1;ABCA5;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 11947:[DB00260 DB00653] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways GO:0006811| ion transport CACNB1;SLC36A2;CACNA1S;CACNG1;CACNA1C;CACNB2;CACNA2D1 11948:[DB00260 DB01147] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2 11949:[DB00260 DB00573] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways 11950:[DB00260 DB00120] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0015842| synaptic vesicle amine transport TH;DDC GO:0010259| multicellular organismal aging DDC;TH GO:0035690| cellular response to drug TH;DDC GO:0009636| response to toxin DDC;SLC7A8 GO:0006520| cellular amino acid metabolic process TAT;SLC7A8;DDC GO:0052314| phytoalexin metabolic process TH;DDC GO:0006865| amino acid transport SLC36A2;SLC7A8;SLC16A10 GO:0033076| isoquinoline alkaloid metabolic process DDC;TH GO:0071363| cellular response to growth factor stimulus TH;DDC GO:0042416| dopamine biosynthetic process TH;DDC GO:0071312| cellular response to alkaloid DDC;TH GO:0042423| catecholamine biosynthetic process PAH;TH;DDC GO:0046684| response to pyrethroid DDC;TH 11951:[DB00260 DB00788] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1A2 11952:[DB00260 DB00869] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways 11953:[DB00260 DB00998] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0009636| response to toxin DDC;HTR1D GO:0035690| cellular response to drug HTR1B;DDC GO:0071312| cellular response to alkaloid DDC;HTR1B 11954:[DB00260 DB13749] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0007623| circadian rhythm DDC;ADCY1 GO:0006811| ion transport ATP1A1;SLC36A2 11955:[DB00260 DB07173] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 11956:[DB00260 DB00539] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 11957:[DB00260 DB09061] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0046219| indolalkylamine biosynthetic process AANAT;DDC GO:0007623| circadian rhythm DDC;AANAT GO:0071312| cellular response to alkaloid DDC;TRPV1 GO:0009636| response to toxin CYP1A1;CYP1B1;CAT;DDC;GPX1 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;SLC36A2;HTR3A;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7 GO:0071363| cellular response to growth factor stimulus TRPV1;HTR3A;OPRD1;CAT;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11958:[DB00260 DB01873] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 11959:[DB00260 DB11135] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways GO:0006520| cellular amino acid metabolic process SCLY;DDC 11960:[DB00260 DB00950] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00950|Fexofenadine HRH1;ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC36A2;SLCO2B1;SLC22A8;SLCO1B1;SLCO1B3;SLCO1A2 11961:[DB00260 DB00397] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways 11962:[DB00260 DB00908] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00908|Quinidine SCN5A;KCNK1;KCNK6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A7;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP2B6;CYP2C9;CYP2C8;ORM1;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A8;ABCC2;SLC22A4;SLCO1B1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport SCN5A;KCNK6;SLCO1B1;SLC22A8;SLC22A5;SLCO1A2;SLC22A4;KCNH2;SLC22A2;KCNK1;SLC36A2;SLC22A1 GO:0035690| cellular response to drug DDC;KCNH2 GO:0009636| response to toxin CYP1A1;SLC22A8;DDC 11963:[DB00260 DB05012] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05012|XEN2174 SLC6A2 common genes common pathways 11964:[DB00260 DB00728] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0071363| cellular response to growth factor stimulus HTR3A;DDC GO:0006811| ion transport CHRNA2;SLCO1A2;HTR3A;SLC36A2;SLC22A1 11965:[DB00260 DB00643] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC 11966:[DB00260 DB00612] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11967:[DB00260 DB00213] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;ATP4A;SLCO1B1 GO:0015992| proton transport SLC36A2;ATP4A 11968:[DB00260 DB01576] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0015842| synaptic vesicle amine transport DDC;SLC18A2 GO:0009636| response to toxin SLC18A2;DDC GO:0042416| dopamine biosynthetic process SLC6A3;DDC 11969:[DB00260 DB01068] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport GABRA5;GABRA3;GABRG1;GABRP;SLC36A2;GABRD;GABRB2;GABRA2;GABRB1;GABRG2;GABRQ;GABRE;GABRA1;GABRA6;GABRA4;TSPO;GABRG3;GABRB3 11970:[DB00260 DB03615] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03615|Ribostamycin P4HB;rpsL common genes common pathways 11971:[DB00260 DB11598] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11598|Antithrombin III human SERPINC1 common genes common pathways 11972:[DB00260 DB00270] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;CACNA2D2;CACNA1S;CACNB2;CACNA2D1;CACNA1H;CACNA1D;CACNA1C 11973:[DB00260 DB00999] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways GO:0006811| ion transport SLC12A3;KCNMA1;SLC36A2 11974:[DB00260 DB00741] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1A2;SLC22A8 GO:0009636| response to toxin SLC22A8;DDC 11975:[DB00260 DB08872] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways GO:0006811| ion transport SLC5A8;SLC5A6;CACNA2D2;SLC36A2;CACNA2D1 11976:[DB00260 DB06421] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06421|Declopramide TOP2A;TOP2B common genes common pathways 11977:[DB00260 DB00233] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0009636| response to toxin DDC;CHUK 11978:[DB00260 DB05155] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05155|CR665 OPRK1 common genes common pathways 11979:[DB00260 DB09080] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways 11980:[DB00260 DB00561] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0006811| ion transport KCNK9;KCNK3;SLC36A2 11981:[DB00260 DB01357] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways 11982:[DB00260 DB06654] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin CYP1A1;MAOB;DDC GO:0006811| ion transport SLC36A2;SLCO3A1 11983:[DB00260 DB00613] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0009636| response to toxin CYP1B1;CYP1A1;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 11984:[DB00260 DB01612] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways 11985:[DB00260 DB09220] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09220|Nicorandil ABCC9 common genes common pathways 11986:[DB00260 DB14518] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0006811| ion transport SLC36A2;TF;ATP1A1 11987:[DB00260 DB00867] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00867|Ritodrine ADRB2;PGD common genes common pathways 11988:[DB00260 DB00169] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin DDC;CYP1A1 11989:[DB00260 DB11901] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0009636| response to toxin SLC22A8;GABRB1;DDC GO:0006811| ion transport GABRE;GABRQ;GABRB1;GABRG2;GABRA4;GABRA6;GABRA1;SLC22A8;SLCO1B1;GABRB3;GABRG3;GABRG1;GABRA3;GABRA5;GABRB2;GABRD;SLC36A2;GABRP;GABRA2;SLC22A2 11990:[DB00260 DB01586] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC10A1;SLC10A2;SLCO1A2 11991:[DB00260 DB00880] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A3 11992:[DB00260 DB05495] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05495|PG-530742 MMP9 common genes common pathways 11993:[DB00260 DB11633] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ6;KCNA5;SLC22A2;KCNQ1;KCNJ11;KCNH2;KCNJ9;SCN5A;KCND3;CACNA1C GO:0035690| cellular response to drug KCNH2;DDC;KCNQ1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 11994:[DB00260 DB12267] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0007623| circadian rhythm DDC;EGFR GO:1902600| SLC47A1;SLC36A2 GO:0035690| cellular response to drug EGFR;DDC GO:0006811| ion transport SLC22A1;SLC36A2 GO:0071363| cellular response to growth factor stimulus EGFR;INSR;ERBB2;DDC 11995:[DB00260 DB04828] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04828|Zomepirac PTGDR2;CYP3A4;ALB common genes common pathways 11996:[DB00260 DB09074] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways 11997:[DB00260 DB00411] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0006811| ion transport SLC36A2;CHRNA2 11998:[DB00260 DB00918] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes common pathways GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin DDC;HTR1D GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071312| cellular response to alkaloid DDC;HTR1B 11999:[DB00260 DB00957] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways 12000:[DB00260 DB04860] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04860|Isatoribine TLR7 common genes common pathways 12001:[DB00260 DB00841] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways 12002:[DB00260 DB11817] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0006811| ion transport SLCO1B3;SLC22A8;SLC36A2;SLC22A2 GO:0009636| response to toxin DDC;SLC22A8 12003:[DB00260 DB01214] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12004:[DB00260 DB08808] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12005:[DB00260 DB14059] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways 12006:[DB00260 DB01309] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01309|Insulin Glulisine INSR common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;INSR 12007:[DB00260 DB00040] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 12008:[DB00260 DB00309] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways 12009:[DB00260 DB06736] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways 12010:[DB00260 DB11988] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11988|Ocrelizumab MS4A1 common genes common pathways 12011:[DB00260 DB09102] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09102|Daclatasvir CYP3A5;CYP3A4;CYP3A43;CYP3A7;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B3;SLCO1B1 12012:[DB00260 DB05018] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05018|Migalastat GLA;UGT1A1 common genes common pathways 12013:[DB00260 DB00674] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0006811| ion transport CHRNA7;CHRNA4;CHRNA5;CHRND;CHRNA2;CHRNB3;CHRNA6;CHRNE;CHRNB1;CHRNA3;CHRNA10;SLC36A2;CHRNA9;CHRNB4;CHRNA1;CHRNB2;CHRNG GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12014:[DB00260 DB06153] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0035690| cellular response to drug DDC;HTR1B GO:0009636| response to toxin HTR1D;DDC 12015:[DB00260 DB00695] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC36A2;SLC22A11;SLC12A1;SLC22A5;SLC22A8 12016:[DB00260 DB00911] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00911|Tinidazole CYP3A4;ABCB11 common genes common pathways 12017:[DB00260 DB09129] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09129|Chromic chloride INSR common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;INSR 12018:[DB00260 DB06796] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways GO:0015992| proton transport SLC11A2;SLC36A2 GO:0006811| ion transport SLC11A2;SLC36A2 GO:1902600| SLC11A2;SLC36A2 12019:[DB00260 DB00384] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0006811| ion transport SLC36A2;SCNN1A;SCNN1B;SCNN1D;SCNN1G 12020:[DB00260 DB00906] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes common pathways GO:0009636| response to toxin DDC;SLC6A1 12021:[DB00260 DB08811] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0035690| cellular response to drug PDE2A;PDE4A;DDC 12022:[DB00260 DB01092] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8;CYP1A1 GO:0006811| ion transport SLCO4C1;ATP1A2;SLCO1C1;SLC36A2;ATP1A3;SLCO1A2;SLCO1B3;SLCO1B1;ATP1A1;SLC22A8 12023:[DB00260 DB01077] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways GO:0006811| ion transport ATP6V1A;SLC36A2 GO:0015992| proton transport SLC36A2;ATP6V1A 12024:[DB00260 DB00942] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00942|Cycrimine CHRM1 common genes common pathways 12025:[DB00260 DB08860] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0006811| ion transport SLCO1B1;SLCO1B3;SLC36A2;SLCO2B1;SLC10A1 12026:[DB00260 DB12010] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0035690| cellular response to drug PRKAA2;EGFR;BRAF;CHEK2;DDC GO:0009636| response to toxin CDK1;CDK4;DDC;EIF2AK2;PDGFRB;LYN GO:0071363| cellular response to growth factor stimulus EGFR;MAPK7;INSR;FYN;NTRK1;ERBB2;RIPK1;DDC;MAP2K5;BMPR1B GO:0007623| circadian rhythm DYRK1A;CDK4;GSK3B;DDC;NTRK1;NTRK2;NTRK3;EGFR 12027:[DB00260 DB00690] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00690|Flurazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP2E1;CYP2A6;CYP3A4;ABCB1;SLC22A2 common genes common pathways GO:0006811| ion transport GABRB3;GABRG3;GABRR3;GABRA4;GABRA6;GABRR1;GABRA1;GABRE;GABRQ;GABRB1;GABRG2;GABRA2;SLC22A2;GABRD;GABRB2;SLC36A2;GABRP;GABRR2;GABRG1;GABRA3;GABRA5 GO:0009636| response to toxin DDC;GABRB1 12028:[DB00260 DB04846] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12029:[DB00260 DB00896] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways 12030:[DB00260 DB00967] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12031:[DB00260 DB06789] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways 12032:[DB00260 DB11827] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways GO:0006811| ion transport SLC5A2;SLC36A2 12033:[DB00260 DB00584] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes common pathways GO:0015992| proton transport SLC15A1;SLC36A2 GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC22A7;SLC22A8;SLCO1A2;SLC36A2;SLC15A1 12034:[DB00260 DB00485] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A1;SLC36A2;SLC15A2 GO:0006811| ion transport SLC36A2;SLC15A1;SLC15A2 12035:[DB00260 DB12070] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLCO1B1;SLC22A8;SLCO1B3;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12036:[DB00260 DB00520] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLCO1B3;SLCO1B1;SLC22A1;SLC36A2 12037:[DB00260 DB05708] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0006811| ion transport CHRNA7;SLC36A2 12038:[DB00260 DB00383] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways 12039:[DB00260 DB00616] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00616|Candoxatril MME;ACE common genes common pathways 12040:[DB00260 DB00180] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways 12041:[DB00260 DB06716] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0006811| ion transport GABRB3;SLC36A2;GABRB2 12042:[DB00260 DB11855] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes common pathways GO:0006811| ion transport SLCO1B3;SLCO1B1;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12043:[DB00260 DB00641] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1A2;SLCO1B1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12044:[DB00260 DB01497] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 12045:[DB00260 DB00259] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12046:[DB00260 DB00683] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00683|Midazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRB1;GABRB3;GABRB2;GABRA6;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP4B1;UGT1A4;CYP2E1;ABCB1;ABCB11 common genes common pathways GO:0006811| ion transport GABRA1;GABRA4;GABRA6;GABRR1;GABRG2;GABRB1;GABRQ;GABRE;GABRG3;GABRB3;GABRR3;GABRP;SLC36A2;GABRB2;GABRD;GABRA5;GABRA3;GABRR2;GABRG1;GABRA2 GO:0009636| response to toxin DDC;GABRB1 12047:[DB00260 DB00306] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA2;GABRG1;GABRA3;GABRA5;GABRD;GABRB2;SLC36A2;GABRP;GRIA2;CHRNA4;GABRB3;CHRNA7;GABRG3;GABRE;GABRQ;GABRB1;GABRG2;GRIK2;GABRA6;GABRA4;GABRA1 12048:[DB00260 DB00279] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC36A2;SLCO1C1;SLCO4C1;SLC10A1;SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2;SLCO4A1 GO:0006520| cellular amino acid metabolic process SLC7A5;DDC GO:0006865| amino acid transport SLC36A2;SLC7A5;SLC16A10 12049:[DB00260 DB04975] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12050:[DB00260 DB00818] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00818|Propofol GABRB2;GABRB3;SCN4A;SCN2A;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP2B6;UGT1A8;UGT1A9;UGT1A1;FAAH;CYP2E1;CYP1B1;CYP1A1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;UGT1A6;ALB common genes common pathways GO:0006811| ion transport SCN4A;SCN2A;GABRA2;GABRG1;GABRA5;GABRA3;SLC36A2;GABRD;GABRB2;GABRP;GABRB3;GABRG3;GABRE;GABRG2;GABRB1;GABRQ;GABRA6;GABRA4;GABRA1 GO:0009636| response to toxin CYP1B1;CYP1A1;DDC;GABRB1 12051:[DB00260 DB00636] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12052:[DB00260 DB05115] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05115|NN344 INSR common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;INSR 12053:[DB00260 DB06042] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways 12054:[DB00260 DB14724] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14724|Emapalumab IFNG common genes common pathways 12055:[DB00260 DB05849] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05849|NCX 950 ADRB2 common genes common pathways 12056:[DB00260 DB04445] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04445|Mercuric iodide SULT2A1 common genes common pathways 12057:[DB00260 DB00751] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0007623| circadian rhythm DDC;HTR7 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12058:[DB00260 DB00765] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00765|Metyrosine TH common genes common pathways GO:0046684| response to pyrethroid DDC;TH GO:0071312| cellular response to alkaloid TH;DDC GO:0042423| catecholamine biosynthetic process TH;DDC GO:0042416| dopamine biosynthetic process DDC;TH GO:0071363| cellular response to growth factor stimulus TH;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;TH GO:0052314| phytoalexin metabolic process DDC;TH GO:0035690| cellular response to drug TH;DDC GO:0010259| multicellular organismal aging TH;DDC GO:0015842| synaptic vesicle amine transport DDC;TH 12059:[DB00260 DB01109] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways 12060:[DB00260 DB00805] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0007623| circadian rhythm DDC;SLC6A4 GO:0009636| response to toxin DDC;SLC6A4;DRD2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12061:[DB00260 DB00199] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0035690| cellular response to drug KCNH2;DDC GO:0006811| ion transport SLC36A2;KCNH2;SLCO1B3;SLCO1B1 12062:[DB00260 DB00374] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways 12063:[DB00260 DB04880] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04880|Enoximone PDE3A common genes common pathways 12064:[DB00260 DB08899] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12065:[DB00260 DB01134] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways 12066:[DB00260 DB00253] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways 12067:[DB00260 DB01323] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12068:[DB00260 DB06781] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways 12069:[DB00260 DB00939] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0006811| ion transport SLCO1C1;SLC36A2;KCNQ3;KCNQ2 12070:[DB00260 DB01892] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 12071:[DB00260 DB00969] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00969|Alosetron HTR3A;CYP2C9;CYP3A4;CYP1A2;CYP2E1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;HTR3A GO:0006811| ion transport HTR3A;SLC36A2 12072:[DB00260 DB06754] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06754|Danaparoid SERPINC1 common genes common pathways 12073:[DB00260 DB13346] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0009636| response to toxin DDC;HDAC6 12074:[DB00260 DB04920] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways GO:0006811| ion transport CACNA1F;CACNA1S;SLC36A2;CACNA1D;CACNA1C GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12075:[DB00260 DB00325] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12076:[DB00260 DB06218] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways GO:0009636| response to toxin DDC;SCN9A GO:0006811| ion transport SCN9A;SCN10A;SLC36A2;SCN3A 12077:[DB00260 DB01006] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways 12078:[DB00260 DB13931] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways 12079:[DB00260 DB07879] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways 12080:[DB00260 DB00257] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;KCNN4 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12081:[DB00260 DB08865] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways 12082:[DB00260 DB00602] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00602|Ivermectin GLRA3;GABRB3;CYP3A4;ABCB1;ABCC1;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport GLRA3;SLCO1B1;SLCO1B3;GABRB3;SLC36A2 12083:[DB00260 DB08813] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0009636| response to toxin FOS;DDC GO:0035690| cellular response to drug MYC;DDC 12084:[DB00260 DB09082] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways 12085:[DB00260 DB00055] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0006811| ion transport CP;SLC36A2 GO:0007623| circadian rhythm DDC;SERPINE1 12086:[DB00260 DB01359] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0035690| cellular response to drug DDC;HTR1B 12087:[DB00260 DB00281] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0006811| ion transport SLC22A5;SCN9A;SCN5A;SLC36A2;SCN10A;SCN4A GO:0035690| cellular response to drug DDC;EGFR GO:0009636| response to toxin DDC;SCN9A GO:0071363| cellular response to growth factor stimulus DDC;EGFR GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0007623| circadian rhythm DDC;EGFR 12088:[DB00260 DB00524] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00524|Metolazone SLC12A3 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A3 12089:[DB00260 DB01110] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01110|Miconazole NOS3;NOS2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;KCNH2;KCNH6;KCNH7;NR1I2;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP11B1;CYP51A1;CYP19A1;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport KCNN3;KCNH6;KCNMB3;SLC36A2;KCNH7;KCNN4;KCNMB1;KCNN1;KCNN2;KCNMA1;KCNMB4;KCNH2;KCNMB2 GO:0035690| cellular response to drug KCNH2;DDC;NOS2 GO:0007623| circadian rhythm NOS2;DDC 12090:[DB00260 DB04884] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0035690| cellular response to drug HTR1B;DDC GO:0071312| cellular response to alkaloid HTR1B;DDC 12091:[DB00260 DB03010] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 12092:[DB00260 DB00323] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways 12093:[DB00260 DB01591] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01591|Solifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4 common genes common pathways 12094:[DB00260 DB13158] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways 12095:[DB00260 DB08893] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08893|Mirabegron ADRB3;CYP3A4;CYP2D6;BCHE;ALB;ORM1;ABCB1;SLCO1A2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport SLC36A2;SLCO1A2 12096:[DB00260 DB05416] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05416|Cardarine PPARD;PPARA common genes common pathways 12097:[DB00260 DB06433] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06433|Tezacitabine RRM1;TYMP common genes common pathways 12098:[DB00260 DB00548] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways 12099:[DB00260 DB00406] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00406|Gentian violet cation SLC22A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A1 12100:[DB00260 DB09401] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0071312| cellular response to alkaloid DDC;BCL2L1 GO:0009636| response to toxin BCL2;DDC 12101:[DB00260 DB05050] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05050|ADL5859 OPRD1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 12102:[DB00260 DB07348] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways 12103:[DB00260 DB07246] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 12104:[DB00260 DB08810] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways 12105:[DB00260 DB01000] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 GO:0006811| ion transport SLC22A5;SLC15A2;SLC15A1;SLC36A2 12106:[DB00260 DB06154] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways 12107:[DB00260 DB06268] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways 12108:[DB00260 DB08916] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways GO:0071363| cellular response to growth factor stimulus ERBB2;DDC;EGFR GO:0035690| cellular response to drug EGFR;DDC GO:0007623| circadian rhythm DDC;EGFR 12109:[DB00260 DB05109] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12110:[DB00260 DB01437] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRB3;GABRG3;GABRE;GABRG2;GABRB1;GABRQ;GABRA4;GABRA6;GABRA1;GABRA2;GABRG1;GABRA5;GABRA3;SLC36A2;GABRD;GABRB2;GABRP 12111:[DB00260 DB06204] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0071363| cellular response to growth factor stimulus HTR3A;OPRD1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport SLC36A2;HTR3A GO:0009636| response to toxin SLC6A4;DDC GO:0007623| circadian rhythm DDC;SLC6A4 12112:[DB00260 DB09028] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0006811| ion transport SLC36A2;CHRNB2;CHRNA3;CHRNA6;CHRNA7;CHRNA4 12113:[DB00260 DB00744] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways 12114:[DB00260 DB00452] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00452|Framycetin rpsL;CXCR4 common genes common pathways 12115:[DB00260 DB00937] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC 12116:[DB00260 DB13191] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways GO:0006811| ion transport SLC6A8;SLC36A2 12117:[DB00260 DB06186] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06186|Ipilimumab CTLA4 common genes common pathways 12118:[DB00260 DB00247] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0035690| cellular response to drug HTR1B;DDC GO:0007623| circadian rhythm DDC;HTR7 GO:0071312| cellular response to alkaloid HTR1B;DDC 12119:[DB00260 DB04977] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways 12120:[DB00260 DB06271] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 12121:[DB00260 DB00367] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0071363| cellular response to growth factor stimulus SRD5A1;DDC 12122:[DB00260 DB00364] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways 12123:[DB00260 DB13956] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0007623| circadian rhythm NCOA2;DDC GO:0015992| proton transport SLC36A2;MT-ATP6 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;DDC GO:0006811| ion transport SLC36A2;SLC22A1;SLCO1C1;SLC22A2;SLCO2B1;SLC22A8;SLCO1B1;SLCO1B3;SLCO1A2;SLC22A3;SLC22A11;SLCO4A1;MT-ATP6;CHRNA4 12124:[DB00260 DB01193] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12125:[DB00260 DB03552] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03552|3-Tyrosine TH common genes common pathways GO:0042423| catecholamine biosynthetic process DDC;TH GO:0071312| cellular response to alkaloid DDC;TH GO:0046684| response to pyrethroid DDC;TH GO:0042416| dopamine biosynthetic process TH;DDC GO:0052314| phytoalexin metabolic process DDC;TH GO:0071363| cellular response to growth factor stimulus DDC;TH GO:0033076| isoquinoline alkaloid metabolic process DDC;TH GO:0010259| multicellular organismal aging TH;DDC GO:0015842| synaptic vesicle amine transport TH;DDC GO:0035690| cellular response to drug DDC;TH 12126:[DB00260 DB00171] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0006520| cellular amino acid metabolic process DDC;ASNS GO:0006811| ion transport CFTR;SLC36A2 GO:0009636| response to toxin ASNS;DDC GO:0071363| cellular response to growth factor stimulus AKT1;DDC GO:0007623| circadian rhythm ASS1;DDC;ADCY1 12127:[DB00260 DB05766] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0009636| response to toxin DRD2;DDC 12128:[DB00260 DB08883] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0006811| ion transport SLC36A2;GRIA1 12129:[DB00260 DB00445] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways 12130:[DB00260 DB06738] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0006811| ion transport GRIN2A;GRIN1;GRIN2D;GRIN2B;GRIN3B;GRIN2C;SLC36A2;GRIN3A GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 12131:[DB00260 DB05223] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0007623| circadian rhythm HDAC3;DDC GO:0009636| response to toxin DDC;HDAC6 12132:[DB00260 DB12698] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways 12133:[DB00260 DB00031] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0007623| circadian rhythm SERPINE1;DDC 12134:[DB00260 DB00642] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways GO:0007623| circadian rhythm DDC;TYMS GO:0006811| ion transport SLC36A2;SLC22A8 GO:0009636| response to toxin DDC;SLC22A8;TYMS 12135:[DB00260 DB02187] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways 12136:[DB00260 DB01207] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways 12137:[DB00260 DB01194] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways 12138:[DB00260 DB09343] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A2 GO:1902600| SLC36A2;SLC47A1 12139:[DB00260 DB00240] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways 12140:[DB00260 DB08910] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08910|Pomalidomide CRBN;TNF;PTGS2;CYP1A2;CYP3A4;ABCB1 common genes common pathways 12141:[DB00260 DB00860] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0006811| ion transport SLCO1A2;SLC36A2 12142:[DB00260 DB06176] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC;HDAC6 GO:0006811| ion transport SLC36A2;SLCO1B3 12143:[DB00260 DB00846] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways 12144:[DB00260 DB06209] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes common pathways 12145:[DB00260 DB01125] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01125|Anisindione GGCX common genes common pathways 12146:[DB00260 DB00851] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC 12147:[DB00260 DB00481] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways 12148:[DB00260 DB01009] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLCO1A2;SLC22A8;SLC22A7;SLC22A11;SLC36A2 12149:[DB00260 DB01536] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways 12150:[DB00260 DB12498] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12498|Mogamulizumab CXCR4 common genes common pathways 12151:[DB00260 DB11967] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0035690| cellular response to drug IL1B;DDC 12152:[DB00260 DB00629] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways 12153:[DB00260 DB01632] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways 12154:[DB00260 DB00562] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways GO:0006811| ion transport SLC12A3;SLC36A2 12155:[DB00260 DB01370] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0006811| ion transport TF;ATP1A1;SLC36A2 12156:[DB00260 DB01114] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0009636| response to toxin SLC6A4;DDC GO:0006811| ion transport SLC22A1;SLC36A2;SLC22A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0007623| circadian rhythm SLC6A4;DDC 12157:[DB00260 DB00054] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways 12158:[DB00260 DB01277] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0071363| cellular response to growth factor stimulus INSR;DDC 12159:[DB00260 DB00461] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways 12160:[DB00260 DB00005] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;TNFRSF1B 12161:[DB00260 DB00310] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00310|Chlorthalidone SLC12A1 common genes common pathways GO:0006811| ion transport SLC12A1;SLC36A2 12162:[DB00260 DB00216] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;HTR1D GO:0035690| cellular response to drug DDC;HTR1B GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0007623| circadian rhythm HTR7;DDC GO:0071312| cellular response to alkaloid DDC;HTR1B 12163:[DB00260 DB00975] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO2B1;SLCO1B3;SLCO1B1 GO:0035690| cellular response to drug DDC;PDE4A 12164:[DB00260 DB00528] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;CACNG1 12165:[DB00260 DB07615] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07615|Tranilast HPGDS;CYP3A4;CYP2C9 common genes common pathways 12166:[DB00260 DB05075] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways 12167:[DB00260 DB00067] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways 12168:[DB00260 DB00983] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12169:[DB00260 DB00282] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00282|Pamidronate FDPS common genes common pathways 12170:[DB00260 DB01341] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways GO:0006811| ion transport SLC36A2;GABRA1 12171:[DB00260 DB00763] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12172:[DB00260 DB08868] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways 12173:[DB00260 DB09274] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways 12174:[DB00260 DB00575] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00575|Clonidine ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP3A5;SLC22A3;SLC22A5;SLC22A4;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 GO:0006811| ion transport SLC22A5;SLC22A3;SLC22A4;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12175:[DB00260 DB08907] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes common pathways GO:0006811| ion transport SLC5A2;SLC36A2;SLC5A1 12176:[DB00260 DB12248] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12248|Tulobuterol ADRB2 common genes common pathways 12177:[DB00260 DB11575] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLCO1B3;SLCO1B1;SLC36A2 12178:[DB00260 DB08881] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08881|Vemurafenib BRAF;CYP1A2;CYP2D6;CYP3A4;CYP2C9;CYP2C8;CYP2B6;ALB;ORM1;ABCC1;ABCG2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0035690| cellular response to drug BRAF;DDC 12179:[DB00260 DB14542] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC22A8;SLCO1A2;SLC36A2 12180:[DB00260 DB00626] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00626|Bacitracin IDE;A2M common genes common pathways 12181:[DB00260 DB11574] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways 12182:[DB00260 DB00583] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0006865| amino acid transport SLC25A29;SLC36A2 GO:0006811| ion transport SLC36A2;SLC22A4;SLC22A8;SLC22A5;SLC22A16;SLCO1B1 GO:0009636| response to toxin DDC;CES1;SLC22A8 GO:0007623| circadian rhythm DDC;CPT1A 12183:[DB00260 DB11828] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11828|Neratinib EGFR;CYP3A4;FMO3;ALB;ORM1;ORM2;ABCB1 common genes common pathways GO:0035690| cellular response to drug DDC;EGFR GO:0071363| cellular response to growth factor stimulus DDC;EGFR GO:0007623| circadian rhythm DDC;EGFR 12184:[DB00260 DB05281] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0009636| response to toxin DDC;BCL2 12185:[DB00260 DB00158] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:1902600| SLC46A1;SLC36A2 GO:0006520| cellular amino acid metabolic process DDC;MTHFR 12186:[DB00260 DB04356] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways 12187:[DB00260 DB00901] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00901|Bitolterol ADRB2 common genes common pathways 12188:[DB00260 DB01041] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01041|Thalidomide CRBN;TNF;NFKB1;FGFR2;PTGS2;ORM1;ORM2;CYP2C19;CYP1A1;CYP2E1;CYP2C9;PTGS1;PTGS2;CYP3A5 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12189:[DB00260 DB01303] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0035690| cellular response to drug DDC;PDE4A GO:0006811| ion transport SLC36A2;SLC22A7 12190:[DB00260 DB08341] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways 12191:[DB00260 DB00234] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00234|Reboxetine SLC6A2;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12192:[DB00260 DB00535] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0006811| ion transport SLC22A8;SLC15A2;SLC22A5;SLC15A1;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8 GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 12193:[DB00260 DB11799] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:1902600| SLC47A1;SLC36A2 12194:[DB00260 DB12329] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways 12195:[DB00260 DB01365] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways 12196:[DB00260 DB01011] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways 12197:[DB00260 DB00219] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00219|Oxyphenonium CHRM1 common genes common pathways 12198:[DB00260 DB13928] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1;SLCO1B3 12199:[DB00260 DB13139] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLCO1B1;SLCO1B3;SLC36A2 12200:[DB00260 DB00313] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes common pathways GO:0009636| response to toxin DDC;SCN9A;SLC22A8 GO:0006811| ion transport SCN11A;SCN8A;SCN9A;SLC22A8;SLC22A5;SCN1A;SCN7A;SLC22A7;SCN5A;SCN1B;SCN10A;SLC36A2;SCN4A;SCN2B;SCN4B;SCN3A;SLCO2B1;SCN3B;SCN2A GO:0046684| response to pyrethroid SCN2B;SCN1B;DDC 12201:[DB00260 DB00354] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00354|Buclizine HRH1;CHRM1 common genes common pathways 12202:[DB00260 DB00476] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00476|Duloxetine SLC6A4;SLC6A2;SLC6A3;CYP1A2;CYP2D6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin SLC6A4;DDC GO:0007623| circadian rhythm SLC6A4;DDC GO:0042416| dopamine biosynthetic process DDC;SLC6A3 12203:[DB00260 DB11963] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes common pathways GO:0007623| circadian rhythm EGFR;DDC GO:0035690| cellular response to drug DDC;EGFR GO:0006811| ion transport SLC36A2;SLC22A1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus EGFR;DDC 12204:[DB00260 DB00586] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00586|Diclofenac PTGS2;PTGS1;ALOX5;SCN4A;ASIC1;KCNQ2;KCNQ3;PLA2G2A;CYP2C9;CYP2C19;CYP1A2;CYP2C8;UGT1A1;UGT2B7;PTGS1;CYP3A4;CYP1A1;CYP2B6;CYP2C18;CYP2E1;TTR;ALB;ABCC4;ABCB1;ABCC1;SLC22A6;SLC22A8;SLCO1C1;SLC22A11;SLCO1B1;ABCB11 common genes common pathways GO:0009636| response to toxin CYP1A1;SLC22A8;DDC GO:0006811| ion transport SLCO1C1;SLC36A2;SCN4A;SLC22A8;SLCO1B1;KCNQ3;ASIC1;SLC22A11;KCNQ2 12205:[DB00260 DB14512] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways 12206:[DB00260 DB00185] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12207:[DB00260 DB09123] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09123|Dienogest PGR;AR;CYP3A4 common genes common pathways 12208:[DB00260 DB00887] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0006811| ion transport SLC22A8;SLCO1A2;SLC12A2;SLC22A11;SLC22A7;SLC12A1;SLC12A4;SLC36A2;CFTR;SLC12A5;SLC10A1 GO:0009636| response to toxin SLC22A8;DDC 12209:[DB00260 DB09325] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 12210:[DB00260 DB00115] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0006520| cellular amino acid metabolic process MTHFR;DDC GO:0006811| ion transport TCN1;SLC36A2;GIF;TCN2 12211:[DB00260 DB06626] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC36A2 12212:[DB00260 DB06454] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0009636| response to toxin DRD2;DDC 12213:[DB00260 DB00677] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0006811| ion transport SLC36A2;TF 12214:[DB00260 DB00136] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways 12215:[DB00260 DB00776] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes common pathways GO:0006811| ion transport SCN5A;SLC36A2 12216:[DB00260 DB14544] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006811| ion transport SLCO1A2;SLC22A8;SLC36A2 GO:0009636| response to toxin SLC22A8;DDC 12217:[DB00260 DB14481] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0006811| ion transport TRPV6;SLC36A2;CACNB3;PKD2L1;CACNA1G;TRPV5;CACNA1S;CATSPER1;RYR3;CACNA1E;CACNB1;CACNA1A;CACNA1I;RYR2;CACNA1F;SLC34A2;SLC20A1;CACNB2;CACNA1H;SLC20A2;PKD1L3;SLC8A1;CACNA1D;CACNB4;SLC34A3;RYR1;SLC34A1;CACNA1C GO:0071363| cellular response to growth factor stimulus SPARC;DDC;CIB1 12218:[DB00260 DB00017] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00017|Salmon Calcitonin CALCR common genes common pathways 12219:[DB00260 DB05266] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0035690| cellular response to drug DDC;PDE4A;PDE4B 12220:[DB00260 DB01427] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0035690| cellular response to drug PDE4B;DDC 12221:[DB00260 DB00349] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin DDC;GABRB1;SLC6A1 GO:0006811| ion transport GABRA2;GABRP;GABRB2;GABRD;SLC36A2;GABRA3;GABRA5;GABRG1;GABRG3;GABRB3;GABRA1;GABRA4;GABRA6;GABRQ;GABRG2;GABRB1;GABRE 12222:[DB00260 DB05229] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways 12223:[DB00260 DB01394] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01394|Colchicine TUBB1;TUBB;CYP3A4;CYP2B6;CYP2C8;CYP2E1;ABCB4;SLC22A3;ABCB1;ABCC1 common genes common pathways GO:0007623| circadian rhythm DDC;ABCB4 GO:0071312| cellular response to alkaloid ABCB4;DDC GO:0006811| ion transport SLC36A2;SLC22A3 12224:[DB00260 DB14541] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006811| ion transport SLCO1A2;SLC22A8;SLC36A2 GO:0009636| response to toxin DDC;SLC22A8 12225:[DB00260 DB01037] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01037|Selegiline MAOB;MAOA;CYP2B6;CYP3A4;CYP2A6;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0009636| response to toxin MAOB;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12226:[DB00260 DB01268] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01268|Sunitinib PDGFRB;FLT1;KIT;KDR;FLT4;FLT3;CSF1R;PDGFRA;CYP3A5;CYP3A7;CYP3A4;ABCC4;ABCB1;ABCC2;ABCG2 common genes common pathways GO:0009636| response to toxin PDGFRB;DDC 12227:[DB00260 DB09318] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09318|Synthetic Conjugated Estrogens, B ESR1;CYP3A4 common genes common pathways 12228:[DB00260 DB00928] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00928|Azacitidine DNMT1;CDA common genes common pathways 12229:[DB00260 DB00564] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00564|Carbamazepine SCN5A;CHRNA4;CHRNB2;NR1I2;CYP3A4;CYP2C8;CYP1A2;CYP2C9;CYP2C19;CYP2B6;CYP3A5;CYP3A7;UGT2B7;UGT1A1;ABCB1;RALBP1;ABCC2 common genes common pathways GO:0006811| ion transport CHRNA4;SCN5A;CHRNB2;SLC36A2 12230:[DB00260 DB13520] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13520|Metergoline SCN2A common genes common pathways GO:0006811| ion transport SCN2A;SLC36A2 12231:[DB00260 DB09059] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways 12232:[DB00260 DB01454] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0015842| synaptic vesicle amine transport DDC;SLC18A2 GO:0009636| response to toxin SLC18A2;SLC6A4;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0007623| circadian rhythm DDC;SLC6A4 12233:[DB00260 DB00204] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0006811| ion transport SLC22A2;SLC36A2;KCNK2;KCNJ12;KCNH2 GO:0035690| cellular response to drug KCNH2;DDC 12234:[DB00260 DB00813] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00813|Fentanyl OPRM1;OPRD1;OPRK1;ABCB1;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 12235:[DB00260 DB00914] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC22A1;SLC36A2;SLC22A2;KCNJ8 12236:[DB00260 DB00469] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A8 GO:0009636| response to toxin SLC22A8;DDC 12237:[DB00260 DB00620] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00620|Triamcinolone NR3C1;CYP3A4;PTGS2;BCHE;SERPINA6 common genes common pathways 12238:[DB00260 DB00454] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00454|Meperidine OPRK1;GRIN1;GRIN2B;GRIN2A;GRIN2C;GRIN2D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;OPRM1;SLC6A3;SLC6A2;SLC6A4;CES1;CYP3A4;CYP2C19;CYP2B6;CYP2D6;CYP1A2;ALB;ORM1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;DDC GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin SLC6A4;DDC;CES1 GO:0006811| ion transport GRIN2C;SLC36A2;GRIN2D;GRIN1;GRIN2B;GRIN2A 12239:[DB00260 DB00489] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;KCNH2 GO:0035690| cellular response to drug DDC;KCNH2 12240:[DB00260 DB01015] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes common pathways GO:0009636| response to toxin GSTP1;DDC 12241:[DB00260 DB02261] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways 12242:[DB00260 DB00248] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin DRD2;HTR1D;DDC GO:0007623| circadian rhythm HTR7;DDC GO:0071312| cellular response to alkaloid HTR1B;DDC 12243:[DB00260 DB00209] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12244:[DB00260 DB00730] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC 12245:[DB00260 DB00359] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes common pathways 12246:[DB00260 DB00761] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0006811| ion transport SLC12A7;SLC36A2;SLC12A4;SLC12A5;SLC12A2;SLC12A6;SLC12A1 12247:[DB00260 DB01028] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport GABRA1;GABRA4;GABRA6;GABRQ;GABRG2;GABRB1;GABRE;GABRG3;GABRB3;ATP2C1;GLRA1;GABRP;GABRD;GABRB2;SLC36A2;GABRA3;GABRA5;GABRG1;GABRA2;KCNA1;GRIA1 GO:0009636| response to toxin DDC;GABRB1 12248:[DB00260 DB11714] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11714|Durvalumab CD274;CD80 common genes common pathways 12249:[DB00260 DB00154] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways 12250:[DB00260 DB12278] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12278|Propiverine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CACNA1C;ADRA1A;CYP3A4;FMO1;FMO3;CYP2B common genes common pathways GO:0006811| ion transport SLC36A2;CACNA1C 12251:[DB00260 DB08908] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways 12252:[DB00260 DB05104] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05104|Asimadoline OPRK1 common genes common pathways 12253:[DB00260 DB09071] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0007623| circadian rhythm DDC;MTNR1A;MTNR1B 12254:[DB00260 DB00712] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00712|Flurbiprofen PTGS1;PTGS2;CYP2C9;UGT2B7;UGT1A1;UGT1A3;UGT1A9;UGT2B4;ALB;ABCC4;SLC22A6 common genes common pathways 12255:[DB00260 DB06335] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06335|Saxagliptin DPP4;CYP3A4;CYP3A5;ABCC1;SLCO4C1;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLCO4C1;SLC36A2;SLC22A8 12256:[DB00260 DB09076] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12257:[DB00260 DB00977] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC10A1 12258:[DB00260 DB00907] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0007623| circadian rhythm DDC;SLC6A4 GO:0009636| response to toxin CES1;DDC;SLC6A4 GO:0006811| ion transport SCN10A;SLC36A2;SLC22A2;SCN11A;SCN5A GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12259:[DB00260 DB00605] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0009636| response to toxin MAPK3;DDC;CYP1A1 12260:[DB00260 DB05838] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05838|OPC-51803 AVPR2 common genes common pathways 12261:[DB00260 DB01355] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0006811| ion transport CHRNA7;GRIA2;CHRNA4;GABRA1;GRIK2;GABRA6;GABRA4;GABRA2;SLC36A2;GABRA5;GABRA3 12262:[DB00260 DB00651] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0035690| cellular response to drug PDE4B;DDC;PDE4A 12263:[DB00260 DB06230] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 12264:[DB00260 DB00457] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A1;KCNH7;SLC22A2;KCNH6;KCNH2;SLC22A3 GO:0009636| response to toxin CYP1A1;DDC GO:0035690| cellular response to drug DDC;KCNH2 12265:[DB00260 DB09048] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12266:[DB00260 DB09216] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways 12267:[DB00260 DB00820] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways 12268:[DB00260 DB07954] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0035690| cellular response to drug DDC;PDE2A 12269:[DB00260 DB11363] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways 12270:[DB00260 DB08889] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways 12271:[DB00260 DB06728] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways 12272:[DB00260 DB00687] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways 12273:[DB00260 DB09301] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways 12274:[DB00260 DB01137] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01137|Levofloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;ABCB1;SLC22A6;SLC22A2;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:1902600| SLC47A1;SLC36A2 GO:0006811| ion transport SLC22A2;SLC36A2;SLC22A4 12275:[DB00260 DB01544] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0006811| ion transport GABRA2;GABRA3;GABRA5;SLC36A2;GABRB3;GABRG2;TSPO;GABRA6;GABRA4;GABRA1 12276:[DB00260 DB01192] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12277:[DB00260 DB04743] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04743|Nimesulide PTGS2;PLA2G2E;LTF;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;LTF 12278:[DB00260 DB09477] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways 12279:[DB00260 DB08795] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 GO:0006811| ion transport SLC36A2;SLC15A1;SLC15A2;SLC22A5 12280:[DB00260 DB00571] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin DDC;CYP1A1 GO:0035690| cellular response to drug HTR1B;DDC GO:0006811| ion transport SLC36A2;SLC22A2 GO:0071312| cellular response to alkaloid DDC;HTR1B 12281:[DB00260 DB05971] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05971|Archexin AKT1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;AKT1 12282:[DB00260 DB00806] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0035690| cellular response to drug DDC;PDE4A;PDE4B 12283:[DB00260 DB01273] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways GO:0006811| ion transport CHRNA7;CHRNA4;CHRNA6;SLC22A2;CHRNA3;SLC36A2;CHRNB2 12284:[DB00260 DB07447] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways 12285:[DB00260 DB14146] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 12286:[DB00260 DB00808] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00808|Indapamide SLC12A3;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A3 12287:[DB00260 DB00159] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0006811| ion transport SLC36A2;TRPV1;SLC8A1 GO:0071363| cellular response to growth factor stimulus TRPV1;DDC GO:0071312| cellular response to alkaloid DDC;TRPV1 12288:[DB00260 DB00727] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways 12289:[DB00260 DB00988] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0042423| catecholamine biosynthetic process DBH;DDC GO:0007623| circadian rhythm HTR7;DDC;SLC6A4 GO:0015842| synaptic vesicle amine transport SLC18A2;DDC GO:0009636| response to toxin MAOB;DRD2;SLC18A2;DDC;SLC6A4 GO:0006811| ion transport SLC36A2;SLC22A1;SLC22A2;HTR3A;SLC22A5;SLC22A3;HTR3B GO:0071363| cellular response to growth factor stimulus DDC;HTR3A 12290:[DB00260 DB00317] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC GO:0035690| cellular response to drug EGFR;DDC GO:0071363| cellular response to growth factor stimulus EGFR;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0007623| circadian rhythm DDC;EGFR 12291:[DB00260 DB01184] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;DRD2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12292:[DB00260 DB11915] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12293:[DB00260 DB01579] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways 12294:[DB00260 DB05964] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0009636| response to toxin DDC;SLC6A4;DRD2 GO:0007623| circadian rhythm SLC6A4;DDC 12295:[DB00260 DB06663] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways 12296:[DB00260 DB00082] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways 12297:[DB00260 DB00870] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways 12298:[DB00260 DB06196] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways 12299:[DB00260 DB01442] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0007623| circadian rhythm DDC;SLC6A4 GO:0009636| response to toxin MAOB;SLC18A2;SLC6A4;DDC GO:0015842| synaptic vesicle amine transport SLC18A2;SLC18A1;DDC 12300:[DB00260 DB00899] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 12301:[DB00260 DB00218] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways 12302:[DB00260 DB01103] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways GO:0006811| ion transport SLC22A2;SLC36A2 12303:[DB00260 DB13165] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways 12304:[DB00260 DB00686] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways 12305:[DB00260 DB06203] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06203|Alogliptin DPP4;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12306:[DB00260 DB11156] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways 12307:[DB00260 DB08935] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08935|Obinutuzumab MS4A1 common genes common pathways 12308:[DB00260 DB05131] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05131|TTP889 F9 common genes common pathways 12309:[DB00260 DB09546] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways 12310:[DB00260 DB08964] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways 12311:[DB00260 DB08879] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08879|Belimumab TNFSF13B common genes common pathways 12312:[DB00260 DB05804] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0006811| ion transport SLCO1B3;SLC22A8;SLCO1B1;SLCO1A2;SLC36A2;SLC10A6;SLCO2B1 GO:0009636| response to toxin SLC22A8;DDC 12313:[DB00260 DB13074] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways 12314:[DB00260 DB11133] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0007623| circadian rhythm DDC;SREBF1 12315:[DB00260 DB01325] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A2;SLC12A1;SLC12A3 12316:[DB00260 DB01353] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0006811| ion transport GABRA2;SLC36A2;GABRA3;GABRA5;CHRNA7;CHRNA4;GRIA2;GABRA1;GRIK2;GABRA6;GABRA4 12317:[DB00260 DB00230] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways GO:0006811| ion transport SLC1A1;CACNA1A;SLC36A2 GO:0006865| amino acid transport SLC1A1;SLC36A2 12318:[DB00260 DB12301] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways 12319:[DB00260 DB13174] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12320:[DB00260 DB00588] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 12321:[DB00260 DB08828] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways 12322:[DB00260 DB07449] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 12323:[DB00260 DB00819] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways 12324:[DB00260 DB00284] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 12325:[DB00260 DB01067] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways 12326:[DB00260 DB01159] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GRIN3B;KCNK3;GABRA2;KCNJ6;GABRA5;GABRA3;GABRG1;KCNN4;GABRP;GLRA1;GRIN3A;SLC36A2;GABRD;GABRB2;ATP2C1;KCNJ3;GABRG3;GRIN2A;GABRB3;GABRG2;GABRB1;GABRQ;GABRE;KCNMA1;GABRA1;GABRA6;GABRA4;KCNK9 12327:[DB00260 DB05889] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways 12328:[DB00260 DB01013] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12329:[DB00260 DB04868] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12330:[DB00260 DB06235] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways 12331:[DB00260 DB14066] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways 12332:[DB00260 DB00703] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12333:[DB00260 DB00203] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00203|Sildenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2D6;CYP1A1;CYP2E1;ABCC4;ABCC5;ABCC10;SLCO1B1;ABCB1 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC GO:0006811| ion transport SLC36A2;SLCO1B1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12334:[DB00260 DB06470] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;GABRA1 12335:[DB00260 DB01340] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2 12336:[DB00260 DB05297] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0009636| response to toxin DDC;BCL2 12337:[DB00260 DB00009] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm DDC;SERPINE1 12338:[DB00260 DB07285] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 12339:[DB00260 DB01628] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01628|Etoricoxib PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12340:[DB00260 DB01001] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways 12341:[DB00260 DB01002] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0006811| ion transport SCN10A;SLC36A2 12342:[DB00260 DB01392] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ15;KCNJ1;KCNJ14;KCNJ12;KCNJ8;KCNJ11;KCNJ10 GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin DRD2;HTR1D;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0071312| cellular response to alkaloid DDC;HTR1B 12343:[DB00260 DB01809] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways 12344:[DB00260 DB00833] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0009636| response to toxin DDC;SLC22A8 GO:0006811| ion transport SLC15A2;SLC22A8;SLC36A2;SLC15A1 GO:0015992| proton transport SLC15A1;SLC36A2;SLC15A2 12345:[DB00260 DB00591] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways 12346:[DB00260 DB01549] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0006811| ion transport GRIN3A;SLC36A2 GO:0009636| response to toxin DDC;DRD2 12347:[DB00260 DB05271] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0009636| response to toxin DRD2;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12348:[DB00260 DB00904] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00904|Ondansetron HTR3A;HTR4;OPRM1;HTR1A;HTR1B;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP2C9;CYP2E1 common genes common pathways GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0071363| cellular response to growth factor stimulus DDC;HTR3A GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;HTR3A GO:0035690| cellular response to drug DDC;HTR1B 12349:[DB00260 DB12483] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways 12350:[DB00260 DB11693] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 12351:[DB00260 DB05152] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05152|NGX267 CHRM1 common genes common pathways 12352:[DB00260 DB02659] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0006811| ion transport SLC36A2;SLC10A2;SLC10A1;SLCO1A2;SLCO1B1;SLC22A8;SLCO1B3;SLC22A7 GO:0009636| response to toxin SLC22A8;CES1;DDC GO:1902600| COX7C;MT-CO2;COX6A2;SLC36A2;COX7A1;MT-CO3;COX4I1;COX5A;COX6C;COX7B;COX6B1;COX8A 12353:[DB00260 DB05110] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05110|VIR201 IFNG common genes common pathways 12354:[DB00260 DB00432] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways GO:0009636| response to toxin TYMS;DDC GO:0007623| circadian rhythm TYMS;DDC 12355:[DB00260 DB12116] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0009636| response to toxin AHR;DDC 12356:[DB00260 DB00307] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00307|Bexarotene RXRA;RXRB;RXRG;CYP3A4;CYP2C9;CYP2C8 common genes common pathways 12357:[DB00260 DB00731] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 12358:[DB00260 DB04932] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways 12359:[DB00260 DB00783] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00783|Estradiol ESR1;ESR2;NR1I2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP3A4;CYP1A2;CYP3A5;CYP3A7;UGT1A1;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0015992| proton transport SLC36A2;MT-ATP6 GO:0009636| response to toxin CYP1B1;CYP1A1;DDC;SLC22A8 GO:0006811| ion transport SLCO4A1;SLC22A11;CHRNA4;MT-ATP6;SLCO1B3;SLCO1B1;SLC22A8;SLC22A3;SLCO1A2;SLCO2B1;SLC22A2;SLC36A2;SLC22A1;SLCO1C1 GO:0007623| circadian rhythm NCOA2;DDC 12360:[DB00260 DB14543] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC36A2;SLC22A8;SLCO1A2 12361:[DB00260 DB01221] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0071312| cellular response to alkaloid DDC;HTR1B GO:0006811| ion transport CHRNA7;HTR3A;SLC36A2;GRIN3A GO:0009636| response to toxin DRD2;HTR1D;DDC GO:0035690| cellular response to drug HTR1B;DDC GO:0071363| cellular response to growth factor stimulus HTR3A;NOS1;DDC;OPRD1 12362:[DB00260 DB05541] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0046684| response to pyrethroid DDC;SCN1B;SCN2B GO:0009636| response to toxin DDC;SCN9A GO:0006811| ion transport SCN1B;SCN10A;SLC36A2;SCN4A;SCN2B;SCN4B;SCN3A;SCN3B;SCN2A;SCN11A;SCN8A;SCN9A;SCN1A;SCN7A;SCN5A 12363:[DB00260 DB09283] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0035690| cellular response to drug PDE4B;PDE2A;DDC;PDE4A 12364:[DB00260 DB00740] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0006865| amino acid transport SLC36A2;SLC7A11 GO:0006811| ion transport SCN5A;SLC36A2 GO:0009636| response to toxin DDC;SLC7A11;CYP1A1 12365:[DB00260 DB09317] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09317|Synthetic Conjugated Estrogens, A ESR1;CYP3A4 common genes common pathways 12366:[DB00260 DB14067] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways 12367:[DB00260 DB00297] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006811| ion transport SCN10A;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12368:[DB00260 DB11994] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12369:[DB00260 DB04841] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC GO:0006811| ion transport SLC36A2;CACNA1G;CACNA1I;CACNA1H GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12370:[DB00260 DB00491] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 12371:[DB00260 DB00335] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12372:[DB00260 DB14068] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways 12373:[DB00260 DB01285] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways 12374:[DB00260 DB08896] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0007623| circadian rhythm NTRK1;DDC GO:0071363| cellular response to growth factor stimulus NTRK1;DDC GO:0009636| response to toxin PDGFRB;DDC GO:0035690| cellular response to drug DDC;BRAF 12375:[DB00260 DB00015] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm DDC;SERPINE1 12376:[DB00260 DB00752] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways GO:0009636| response to toxin MAOB;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12377:[DB00260 DB09013] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12378:[DB00260 DB00277] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC22A7;SLC36A2 GO:0009636| response to toxin DDC;CYP1A1;CYP1B1 GO:0035690| cellular response to drug PDE4A;DDC;PDE4B 12379:[DB00260 DB12789] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12789|Dinoprost PTGDR2 common genes common pathways 12380:[DB00260 DB01244] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01244|Bepridil CACNA1A;CACNA1H;CACNA2D2;ATP1A1;KCNQ1;TNNC1;CALM1;PDE1B;PDE1A;KCNH2;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport CACNA1A;KCNQ1;SLC36A2;CACNA2D2;ATP1A1;KCNH2;CACNA1H GO:0035690| cellular response to drug KCNQ1;KCNH2;DDC 12381:[DB00260 DB01175] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0007623| circadian rhythm DDC;SLC6A4 GO:0042416| dopamine biosynthetic process SLC6A3;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0009636| response to toxin SLC6A4;DDC 12382:[DB00260 DB00295] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12383:[DB00260 DB01393] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 GO:0009636| response to toxin DDC;CYP1A1 12384:[DB00260 DB00447] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC15A1;SLC36A2;SLC15A2 GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2 12385:[DB00260 DB00492] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006811| ion transport SLC36A2;SLC15A1;SLC15A2 GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 12386:[DB00260 DB00986] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways 12387:[DB00260 DB05443] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05443|ADL 10-0101 OPRK1 common genes common pathways 12388:[DB00260 DB00563] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00563|Methotrexate DHFR;DHFR;AOX1;MTHFR;PGD;FPGS;TYMS;ATIC;GGH;CYP3A4;ALB;ABCC3;ABCC4;ABCC1;SLC22A6;ABCC10;SLC22A8;ABCC2;ABCB1;SLCO1A2;SLC16A1;ABCC11;SLCO1B3;SLC22A11;SLCO1C1;SLCO3A1;ABCG2;SLC22A7;SLC46A1;SLCO1B1;SLCO4C1;SLC19A1;FOLR1 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC;TYMS GO:0006811| ion transport SLC22A11;SLC22A7;SLCO3A1;SLCO1A2;SLCO1B1;SLC22A8;SLCO1B3;SLCO4C1;SLCO1C1;SLC36A2 GO:0006520| cellular amino acid metabolic process DDC;MTHFR GO:1902600| SLC46A1;SLC36A2 GO:0007623| circadian rhythm TYMS;DDC 12389:[DB00260 DB00217] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0006811| ion transport SLC36A2;KCNJ1 12390:[DB00260 DB01281] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01281|Abatacept CD80;CD86 common genes common pathways 12391:[DB00260 DB01090] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways GO:0006811| ion transport CHRNA3;CHRNA10;SLC36A2;CHRNB4 12392:[DB00260 DB12140] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0035690| cellular response to drug IL1B;DDC 12393:[DB00260 DB09262] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways 12394:[DB00260 DB01088] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0006811| ion transport SLCO2B1;SLC36A2;SLCO3A1 GO:0035690| cellular response to drug PDE4B;PDE4A;DDC 12395:[DB00260 DB05294] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes common pathways GO:0007623| circadian rhythm DDC;EGFR GO:0035690| cellular response to drug DDC;EGFR GO:0006811| ion transport SLC36A2;SLC22A2 GO:0071363| cellular response to growth factor stimulus EGFR;DDC 12396:[DB00260 DB04845] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways 12397:[DB00260 DB06413] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0042416| dopamine biosynthetic process DDC;SLC6A3 12398:[DB00260 DB00544] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0007623| circadian rhythm DDC;TYMS GO:0006520| cellular amino acid metabolic process DDC;MTHFR GO:0006811| ion transport SLC22A7;SLC36A2 GO:0035690| cellular response to drug UMPS;DDC;PPAT GO:0009636| response to toxin DDC;TYMS 12399:[DB00260 DB00542] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC36A2;SLC15A1;SLC15A2 GO:0006520| cellular amino acid metabolic process MTHFR;DDC GO:0006811| ion transport SLC15A2;SLC15A1;SLC36A2 12400:[DB00260 DB08870] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways 12401:[DB00260 DB03683] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 12402:[DB00260 DB08873] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08873|Boceprevir CYP3A4;CYP3A5;ABCB1 common genes common pathways 12403:[DB00260 DB01413] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2;SLC22A5 GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 12404:[DB00260 DB09119] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0006811| ion transport P2RX4;SLC36A2 12405:[DB00260 DB00201] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin CYP1A1;CYP1B1;DDC GO:0035690| cellular response to drug PDE2A;PDE4B;PDE4A;DDC GO:0006811| ion transport SLC36A2;ITPR1;ITPR3;ITPR2;RYR1 12406:[DB00260 DB00972] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00972|Azelastine HRH1;CYP1A2;CYP3A4;CYP2C19;CYP1A1;CYP3A5;CYP2C9;CYP2C8;CYP2D6;CYP2A6;CYP2B6;CYP2E1;ABCB1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin CYP1A1;DDC 12407:[DB00260 DB12455] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways 12408:[DB00260 DB00774] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A1;KCNMA1;ATP1A1 12409:[DB00260 DB00402] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00402|Eszopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA2;GABRG1;GABRA5;GABRA3;SLC36A2;GABRB2;GABRD;GABRP;GABRB3;GABRG3;GABRE;GABRB1;GABRG2;GABRQ;GABRA6;GABRA4;TSPO;GABRA1 12410:[DB00260 DB01567] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0006811| ion transport GABRG3;GABRB3;GABRR3;GABRA1;GABRR1;GABRG2;GABRB1;GABRE;GABRA2;GABRP;SLC36A2;GABRD;GABRB2;GABRA5;GABRA3;GABRG1;GABRR2 GO:0009636| response to toxin GABRB1;DDC 12411:[DB00260 DB00480] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways 12412:[DB00260 DB00771] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00771|Clidinium CHRM1 common genes common pathways 12413:[DB00260 DB00700] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00700|Eplerenone NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP11B2 common genes common pathways 12414:[DB00260 DB00659] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0035524| proline transmembrane transport SLC36A2;SLC36A1 GO:0015808| L-alanine transport SLC36A2;SLC36A1 GO:0006865| amino acid transport SLC36A1;SLC36A2 GO:0015992| proton transport SLC36A2;SLC36A1 GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport GABRA2;GRIN3B;GABRD;GABRB2;GRIN3A;SLC36A2;GABRP;GRIN2C;GABRG1;GABRA3;GABRA5;GABRB3;GRIN2A;GABRG3;SLC36A1;GRIN2B;GABRA4;GABRA6;GABRA1;GRIN1;GRIN2D;GABRE;GABRQ;GABRG2;GABRB1 GO:0015816| glycine transport SLC36A2;SLC36A1 GO:0015824| proline transport SLC36A1;SLC36A2 GO:1902600| SLC36A2;SLC36A1 12415:[DB00260 DB01609] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways 12416:[DB00260 DB09043] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09043|Albiglutide GLP1R common genes common pathways 12417:[DB00260 DB00412] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12418:[DB00260 DB06719] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways 12419:[DB00260 DB01119] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0006811| ion transport KCNJ11;KCNMA1;ATP1A1;SLC12A3;SLC36A2 12420:[DB00260 DB04908] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04908|Flibanserin HTR1A;HTR2A;DRD4;CYP3A4 common genes common pathways 12421:[DB00260 DB00842] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways GO:0006811| ion transport GABRQ;GABRB1;GABRG2;GABRE;GABRA1;GABRA6;GABRR1;GABRA4;GABRR3;GABRG3;GABRB3;GABRA3;GABRA5;GABRR2;GABRG1;GABRP;GABRB2;GABRD;SLC36A2;GABRA2 GO:0009636| response to toxin DDC;GABRB1 12422:[DB00260 DB04552] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0006811| ion transport CLCNKA;SLC36A2 12423:[DB00260 DB00440] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00440|Trimethoprim TYMS;DHFR;CYP3A4;CYP2C8;CYP2C9;ABCB1;SLC22A2 common genes common pathways GO:0007623| circadian rhythm DDC;TYMS GO:0006811| ion transport SLC36A2;SLC22A2 GO:0009636| response to toxin TYMS;DDC 12424:[DB00260 DB00184] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0006811| ion transport SLC22A3;SLC22A4;CHRNA6;SLC22A5;CHRNA4;CHRNA5;CHRNA2;CHRNB3;CHRNA7;CHRNB2;SLC22A1;SLC36A2;CHRNA9;CHRNB4;CHRNA3;CHRNA10;SLC22A2 GO:0009636| response to toxin MAOB;CYP1A1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12425:[DB00260 DB06777] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways 12426:[DB00260 DB04630] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1A2;SLC22A5 12427:[DB00260 DB00482] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00482|Celecoxib PTGS2;PDPK1;CA2;CA3;ABCB5;ABCG2;ABCB1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;ABCC4;ABCB11 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12428:[DB00260 DB01035] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:1902600| SLC36A2;SLC47A1 GO:0006811| ion transport SLC22A2;SLC22A1;SLC36A2;SCN5A;SLC22A3;KCNH2;SLC22A4;SLC22A5 GO:0035690| cellular response to drug DDC;KCNH2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12429:[DB00260 DB05969] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05969|SNS-032 CDK7;VEGFA common genes common pathways 12430:[DB00260 DB00809] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways 12431:[DB00260 DB00648] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways 12432:[DB00260 DB02901] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways 12433:[DB00260 DB06710] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLCO1A2;SLC22A8;SLC36A2 12434:[DB00260 DB07477] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07477|Felbinac CTSL common genes common pathways 12435:[DB00260 DB01156] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLC36A2;SLC22A2;CHRNA3 GO:0042416| dopamine biosynthetic process SLC6A3;DDC 12436:[DB00260 DB00496] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12437:[DB00260 DB00807] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00807|Proparacaine SCN10A common genes common pathways GO:0006811| ion transport SLC36A2;SCN10A 12438:[DB00260 DB00318] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0071363| cellular response to growth factor stimulus DDC;OPRD1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0006811| ion transport SLC36A2;SLC22A1 12439:[DB00260 DB00443] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways 12440:[DB00260 DB01217] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways 12441:[DB00260 DB06791] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways 12442:[DB00260 DB01062] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12443:[DB00260 DB00780] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways GO:0009636| response to toxin DDC;MAOB GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12444:[DB00260 DB05767] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0035690| cellular response to drug IL1B;DDC 12445:[DB00260 DB06820] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12446:[DB00260 DB01320] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SCN5A;SLC36A2 12447:[DB00260 DB00500] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways 12448:[DB00260 DB00804] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12449:[DB00260 DB01388] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01388|Mibefradil CACNA1G;CACNA1H;CACNA1C;CACNA1D;CACNA1F;CACNA1I;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP1A1;ABCB1 common genes common pathways GO:0006811| ion transport CACNA1H;CACNB2;CACNA1D;CACNB4;CACNA1C;CACNA1G;CACNA1S;SLC36A2;CACNB3;CACNA1I;CACNA1F;CACNB1 GO:0009636| response to toxin CYP1A1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12450:[DB00260 DB01115] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01115|Nifedipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CALM1;KCNA1;CACNA1H;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2A6;CYP2C8;CYP2D6;CYP2E1;CYP1A1;CYP2B6;ABCC3;ABCB1;ABCC2;SLCO1B1;ABCB11 common genes common pathways GO:0009636| response to toxin CYP1A1;DDC GO:0006811| ion transport CACNA2D1;CACNB2;SLCO1B1;CACNA1H;CACNA1D;CACNA1C;SLC36A2;CACNA1S;KCNA1 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12451:[DB00260 DB09118] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0019752| carboxylic acid metabolic process DDC;LDHA;LDHB GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport GABRG3;GABRB3;GABRB1;GABRG2;GABRQ;GABRE;GABRA1;GABRA6;GABRA4;GABRA2;GABRA5;GABRA3;GABRG1;GABRP;SLC36A2;GABRB2;GABRD GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12452:[DB00260 DB11943] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways 12453:[DB00260 DB01558] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01558|Bromazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0009636| response to toxin DDC;GABRB1 GO:0006811| ion transport GABRA2;GABRA3;GABRA5;GABRG1;GABRR2;GABRP;GABRD;GABRB2;SLC36A2;GABRR3;GABRG3;GABRB3;GABRQ;GABRB1;GABRG2;GABRE;GABRA1;GABRA6;GABRR1;GABRA4 12454:[DB00260 DB08932] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes common pathways 12455:[DB00260 DB13975] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12456:[DB00260 DB00042] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 12457:[DB00260 DB00254] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A8;SLC22A11 GO:0009636| response to toxin SLC22A8;DDC 12458:[DB00260 DB00938] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00938|Salmeterol ADRB2;ADRB1;ADRB3;CYP3A4;CYP3A5;CYP3A7;CYP2C8 common genes common pathways 12459:[DB00260 DB13955] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006811| ion transport SLC22A11;SLCO4A1;MT-ATP6;CHRNA4;SLC22A8;SLCO1B1;SLCO1B3;SLCO1A2;SLC22A3;SLC22A2;SLCO2B1;SLC36A2;SLCO1C1;SLC22A1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;DDC GO:0015992| proton transport SLC36A2;MT-ATP6 GO:0007623| circadian rhythm NCOA2;DDC 12460:[DB00260 DB00546] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0006811| ion transport GABRP;SLC36A2;GABRD;GABRB2;GABRA5;GABRA3;GABRR2;GABRG1;GABRA2;GABRA1;GABRR1;GABRG2;GABRB1;GABRE;GABRG3;GABRB3;GABRR3 GO:0009636| response to toxin DDC;GABRB1 12461:[DB00260 DB14700] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14700|Damoctocog alfa pegol F8 common genes common pathways 12462:[DB00260 DB00418] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0006811| ion transport CHRNA7;GRIN2A;GRIA2;CHRNA4;GABRA4;GRIK2;GABRA6;GRIN2B;GABRA1;GRIN1;GRIN2D;GABRA2;GRIN3B;GRIN3A;SLC36A2;GRIN2C;GABRA5;GABRA3 12463:[DB00260 DB09095] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways 12464:[DB00260 DB00428] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12465:[DB00260 DB09244] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways 12466:[DB00260 DB00387] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways 12467:[DB00260 DB11718] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0035690| cellular response to drug DDC;BRAF 12468:[DB00260 DB00956] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00956|Hydrocodone OPRM1;OPRD1;CYP2D6;CYP3A4 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12469:[DB00260 DB01235] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes DDC common pathways GO:0042423| catecholamine biosynthetic process DDC GO:0071312| cellular response to alkaloid DDC GO:0019752| carboxylic acid metabolic process DDC GO:0046684| response to pyrethroid DDC GO:0007623| circadian rhythm DDC GO:0042416| dopamine biosynthetic process DDC GO:0046219| indolalkylamine biosynthetic process DDC GO:0052314| phytoalexin metabolic process DDC GO:0006865| amino acid transport SLC36A2;SLC7A5;SLC16A10;SLC7A8 GO:0015992| proton transport SLC36A2;SLC15A1 GO:0033076| isoquinoline alkaloid metabolic process DDC GO:0071363| cellular response to growth factor stimulus DDC GO:0042427| serotonin biosynthetic process DDC GO:0015842| synaptic vesicle amine transport DDC GO:0010259| multicellular organismal aging DDC GO:0009636| response to toxin DRD2;SLC7A8;DDC GO:0035690| cellular response to drug DDC GO:0006811| ion transport SLC15A1;SLC36A2 GO:0006520| cellular amino acid metabolic process SLC7A5;DDC;SLC7A8 12470:[DB00260 DB02709] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes common pathways GO:0042416| dopamine biosynthetic process DDC;SNCA GO:0007623| circadian rhythm DDC;MTNR1B;MTNR1A GO:0009636| response to toxin AHR;CYP1A1;CYP1B1;DDC GO:0071363| cellular response to growth factor stimulus AKT1;DDC 12471:[DB00260 DB00590] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00590|Doxazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;CYP2C19;CYP2D6;CYP3A4;ORM1;ABCB1;SLC22A1 common genes common pathways GO:0006811| ion transport KCNH2;SLC22A1;KCNH7;SLC36A2;KCNH6 GO:0035690| cellular response to drug KCNH2;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12472:[DB00260 DB01278] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways 12473:[DB00260 DB00333] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00333|Methadone OPRM1;GRIN3A;CHRNA10;OPRD1;HTR3A;LY96;ORM2;CYP3A4;CYP2C19;CYP3A5;CYP3A7;CYP2D6;CYP2B6;CYP2C8;CYP19A1;CYP1A2;CYP2C18;CYP2C9;ABCB1 common genes common pathways GO:0006811| ion transport GRIN3A;SLC36A2;HTR3A;CHRNA10 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0071363| cellular response to growth factor stimulus OPRD1;DDC;HTR3A 12474:[DB00260 DB01348] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006811| ion transport SLC15A2;SLC15A1;SLC36A2 GO:0015992| proton transport SLC15A2;SLC15A1;SLC36A2 12475:[DB00260 DB00961] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00961|Mepivacaine SCN10A common genes common pathways GO:0006811| ion transport SCN10A;SLC36A2 12476:[DB00260 DB09054] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLCO1B1;SLCO1B3;SLC36A2 12477:[DB00260 DB01565] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 12478:[DB00260 DB14575] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0006811| ion transport P2RX4;SLC36A2 12479:[DB00260 DB09270] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways 12480:[DB00260 DB00327] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 12481:[DB00260 DB08439] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0006811| ion transport SLC36A2;LTF 12482:[DB00260 DB00073] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00073|Rituximab MS4A1 common genes common pathways 12483:[DB00260 DB02703] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport SLCO1B1;SLC36A2 12484:[DB00260 DB00518] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;CYP1A1 12485:[DB00260 DB00268] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0071312| cellular response to alkaloid HTR1B;DDC GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin DDC;HTR1D;DRD2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12486:[DB00260 DB01196] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways 12487:[DB00260 DB06263] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways 12488:[DB00260 DB00186] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0006811| ion transport GABRP;GABRB2;GABRD;SLC36A2;GABRA3;GABRA5;GABRG1;GABRA2;GABRA1;TSPO;GABRA6;GABRA4;GABRQ;GABRG2;GABRB1;GABRE;GABRG3;GABRB3 GO:0009636| response to toxin GABRB1;DDC 12489:[DB00260 DB05710] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways GO:0006811| ion transport CHRNA3;SLC36A2 12490:[DB00260 DB00426] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways 12491:[DB00260 DB06809] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06809|Plerixafor CXCR4 common genes common pathways 12492:[DB00260 DB01082] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways 12493:[DB00260 DB00753] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0006811| ion transport GABRB3;GABRG3;CHRNA4;ATP2C1;GABRA6;GABRA4;GABRA1;GABRE;GABRQ;GABRB1;GABRG2;GABRA2;KCNA1;GRIA1;GABRD;GABRB2;SLC36A2;GLRA1;GABRP;GABRG1;CHRNB2;GABRA3;GABRA5 GO:0009636| response to toxin GABRB1;DDC 12494:[DB00260 DB01140] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways GO:0015992| proton transport SLC15A1;SLC36A2;SLC15A2 GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC15A1;SLC36A2;SLC22A5;SLC15A2;SLC22A8 12495:[DB00260 DB12161] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0015842| synaptic vesicle amine transport DDC;SLC18A2 GO:0009636| response to toxin SLC18A2;DDC GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12496:[DB00260 DB08909] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12497:[DB00260 DB01201] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12498:[DB00260 DB00688] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00688|Mycophenolate mofetil IMPDH1;IMPDH2;UGT1A1;UGT1A7;UGT1A6;UGT1A9;UGT2B7;UGT1A8;UGT1A10;CES1;CES2;CYP3A4;CYP3A5;CYP2C8;ALB;SLCO1B1;SLCO1B3;ABCC2;ABCG2;ABCB1 common genes common pathways GO:0007623| circadian rhythm DDC;IMPDH2 GO:0006811| ion transport SLC36A2;SLCO1B3;SLCO1B1 GO:0009636| response to toxin CES1;DDC 12499:[DB00260 DB00747] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0006811| ion transport CHRNB2;SLC36A2;CHRNA4 12500:[DB00260 DB01117] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways GO:0015992| proton transport MT-CYB;SLC36A2 GO:0009636| response to toxin DDC;MT-CYB 12501:[DB00260 DB04855] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes common pathways GO:0006811| ion transport CACNA1D;CACNB4;CACNA1C;SCN1A;KCNH2;KCNK2;CACNB2;CACNA1F;CACNB1;CACNA1S;SLC36A2;CACNB3 GO:0035690| cellular response to drug KCNH2;DDC GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 12502:[DB00260 DB00343] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00343|Diltiazem CACNG1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2D6;CYP2C8;ABCB1 common genes common pathways GO:0006811| ion transport CACNG1;SLC36A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12503:[DB00260 DB00844] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 12504:[DB00260 DB00624] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00624|Testosterone AR;ESR1;NR3C2;CYP3A5;CYP19A1;CYP11A1;MAOA;CYP3A7;CYP3A4;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes common pathways GO:0006811| ion transport SLC36A2;SLC10A1;SLC22A3;SLC22A4;SLCO1A2;SLC22A8;SLC22A7 GO:0009636| response to toxin SLC22A8;DDC;CYP1A1;CYP1B1 12505:[DB00260 DB01112] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways GO:0015992| proton transport SLC36A2;SLC15A1;SLC15A2 GO:0006811| ion transport SLC36A2;SLC15A1;SLC15A2 12506:[DB00260 DB00934] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0009636| response to toxin DDC;DRD2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0007623| circadian rhythm DDC;HTR7 12507:[DB00260 DB11386] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11386|Chlorobutanol KCNH2 common genes common pathways GO:0006811| ion transport SLC36A2;KCNH2 GO:0035690| cellular response to drug DDC;KCNH2 12508:[DB00260 DB13951] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways 12509:[DB00260 DB14003] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;TTPA 12510:[DB00260 DB11642] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0006811| ion transport KCNH2;SLC22A1;SLC36A2 GO:0035690| cellular response to drug KCNH2;DDC 12511:[DB00260 DB07177] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 12512:[DB00260 DB03793] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC22A8;SLC15A1;SLC36A2;SLCO2B1 GO:0015992| proton transport SLC36A2;SLC15A1 GO:0042416| dopamine biosynthetic process DDC;DAO 12513:[DB00260 DB02925] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB02925|Piretanide SLC12A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A1 12514:[DB00260 DB06273] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06273|Tocilizumab IL6R;CYP3A4 common genes common pathways 12515:[DB00260 DB00603] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways 12516:[DB00260 DB06480] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways 12517:[DB00260 DB13293] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13293|Ipecac CYP2D6;CYP3A4 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12518:[DB00260 DB00472] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00472|Fluoxetine SLC6A4;KCNH2;HTR2C;CKS1B;CHRNA2;CHRNA3;CHRNB4;CYP2C19;CYP2D6;CYP2C9;CYP2B;CYP1A2;CYP3A4;CYP2B6;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0035690| cellular response to drug KCNH2;DDC GO:0009636| response to toxin DDC;SLC6A4 GO:0006811| ion transport KCNH2;CHRNA2;SLC36A2;CHRNB4;CHRNA3 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0007623| circadian rhythm DDC;SLC6A4 12519:[DB00260 DB01250] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01250|Olsalazine TPMT;IFNG common genes common pathways 12520:[DB00260 DB00881] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0015992| proton transport SLC15A2;SLC36A2;SLC15A1 GO:0009636| response to toxin SLC22A8;DDC GO:0006811| ion transport SLC15A1;SLC36A2;SLC22A8;SLC15A2 12521:[DB00260 DB06403] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1;SLCO1B3 12522:[DB00260 DB01333] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways GO:1902600| SLC47A1;SLC36A2 GO:0006811| ion transport SLC22A5;SLC15A2;SLC15A1;SLC36A2 GO:0015992| proton transport SLC36A2;SLC15A1;SLC15A2 12523:[DB00260 DB01339] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways GO:0006811| ion transport CHRNA2;SLC36A2 12524:[DB00260 DB13857] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13857|Demegestone PGR;CYP3A4 common genes common pathways 12525:[DB00260 DB05939] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05939|MK-0354 GPER1 common genes common pathways 12526:[DB00260 DB00952] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0035690| cellular response to drug HTR1B;DDC GO:0009636| response to toxin HTR1D;DDC GO:0071312| cellular response to alkaloid HTR1B;DDC 12527:[DB00260 DB00909] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00909|Zonisamide SCN1A;SCN2A;SCN3A;SCN4A;SCN5A;SCN9A;SCN11A;SCN1B;SCN2B;SCN3B;SCN4B;CACNA1G;CACNA1H;CACNA1I;CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA8;CA9;CA10;CA11;CA12;CA13;CA14;MAOB;MAOA;CYP3A4;AOX1;CYP2C19;UGT1A1;CYP3A5 common genes common pathways GO:0006811| ion transport SCN9A;SCN11A;CACNA1H;SCN1A;SCN5A;CACNA1G;SCN1B;SLC36A2;SCN4A;CACNA1I;SCN3B;SCN3A;SCN4B;SCN2B;SCN2A GO:0009636| response to toxin MAOB;SCN9A;DDC GO:0046684| response to pyrethroid SCN2B;SCN1B;DDC 12528:[DB00260 DB00222] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0006811| ion transport KCNJ1;SLC36A2;KCNJ11 12529:[DB00260 DB00721] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0042416| dopamine biosynthetic process DDC;SLC6A3 GO:0006811| ion transport CHRNA2;KCNN2;KCNN1;KCNMB2;KCNMB4;KCNMA1;HTR3A;KCNMB3;KCNN3;KCNMB1;SCN10A;KCNN4;SLC36A2;GRIN3A GO:0009636| response to toxin MAOB;DDC GO:0071363| cellular response to growth factor stimulus DDC;HTR3A 12530:[DB00260 DB00273] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00273|Topiramate GABRA1;SCN1A;GRIK1;CA2;CA4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CA1;CA3;CYP2C19;CYP3A4 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA5;GABRA3;GABRG1;GABRP;SLC36A2;GABRD;GABRB2;GABRA2;GABRG2;GABRB1;GABRQ;GABRE;GABRA1;GABRA4;GABRA6;GRIK1;SCN1A;GABRG3;GABRB3 12531:[DB00260 DB14507] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006811| ion transport SLC36A2;GRIA3 GO:0007623| circadian rhythm DDC;GSK3B 12532:[DB00260 DB00056] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 12533:[DB00260 DB00996] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0006811| ion transport GRIN2B;CACNA2D1;CACNA1B;GRIN2D;GRIN1;GRIN2A;GRIN3A;SLC36A2;CACNA2D2;GRIN2C;GRIN3B 12534:[DB00260 DB06637] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0009636| response to toxin DDC;KCNC2;KCNC1 GO:0035690| cellular response to drug KCNC1;DDC GO:0006811| ion transport KCNA10;KCND3;KCND1;KCNA2;KCNB2;KCND2;KCNA6;KCNC1;KCNC2;KCNA4;KCNA1;KCNA7;KCNA5;SLC22A2;KCNB1;KCNA3;KCNC3;SLC36A2 12535:[DB00260 DB06207] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0071312| cellular response to alkaloid ABCB4;DDC GO:0007623| circadian rhythm ABCB4;DDC 12536:[DB00260 DB01259] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0035690| cellular response to drug EGFR;DDC GO:0071363| cellular response to growth factor stimulus DDC;ERBB2;EGFR GO:0007623| circadian rhythm EGFR;DDC 12537:[DB00260 DB01406] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways 12538:[DB00260 DB00862] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways 12539:[DB00260 DB01215] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0009636| response to toxin GABRB1;DDC GO:0006811| ion transport GABRA1;GABRA4;GABRR1;GABRA6;GABRQ;GABRB1;GABRG2;GABRE;GABRG3;GABRB3;GABRR3;GABRP;GABRB2;GABRD;SLC36A2;GABRA3;GABRA5;GABRG1;GABRR2;GABRA2 12540:[DB00260 DB00448] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0009636| response to toxin CYP1B1;CYP1A1;DDC;SLC22A8 GO:0006811| ion transport SLC36A2;ATP4A;SLC22A8 GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0015992| proton transport SLC36A2;ATP4A 12541:[DB00260 DB01181] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways 12542:[DB00260 DB06708] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12543:[DB00260 DB00672] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006811| ion transport SLC15A1;SLC36A2;SLC15A2 GO:0015992| proton transport SLC15A1;SLC36A2;SLC15A2 12544:[DB00260 DB08437] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways 12545:[DB00260 DB13170] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB13170|Plecanatide GUCY1A2 common genes common pathways 12546:[DB00260 DB01073] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways 12547:[DB00260 DB00436] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways GO:0006811| ion transport SLC12A3;KCNMA1;SLC36A2 12548:[DB00260 DB00092] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways 12549:[DB00260 DB00990] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways 12550:[DB00260 DB00484] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways 12551:[DB00260 DB05207] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05207|SD118 TNF;IL1R1 common genes common pathways 12552:[DB00260 DB11737] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0071363| cellular response to growth factor stimulus EGFR;DDC GO:0035690| cellular response to drug EGFR;DDC GO:0007623| circadian rhythm EGFR;DDC 12553:[DB00260 DB11098] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways GO:0006811| ion transport SLC36A2;SLC12A2;SLC12A1 12554:[DB00260 DB00316] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00316|Acetaminophen PTGS2;PTGS1;FAAH;TRPV1;GSTP1;CYP2E1;CYP1A2;CYP3A4;CYP2D6;CYP1A1;CYP2A6;CYP2C8;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9;SLC22A6;ABCB1 common genes common pathways GO:0009636| response to toxin DDC;GSTP1;CYP1A1 GO:0006811| ion transport SLC36A2;TRPV1 GO:0071363| cellular response to growth factor stimulus DDC;TRPV1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0071312| cellular response to alkaloid DDC;TRPV1 12555:[DB00260 DB09297] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB09297|Paritaprevir CYP3A4;CYP3A5;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport SLC36A2;SLCO1B1;SLCO1B3 12556:[DB00260 DB00905] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways 12557:[DB00260 DB01225] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways 12558:[DB00260 DB01020] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways 12559:[DB00260 DB01260] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways 12560:[DB00260 DB01065] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0046219| indolalkylamine biosynthetic process ASMT;DDC GO:0007623| circadian rhythm DDC;MTNR1B;MTNR1A GO:0006811| ion transport SLC22A8;SLC36A2 GO:0009636| response to toxin CYP1B1;CYP1A1;DDC;SLC22A8 12561:[DB00260 DB04830] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04830|Buformin SLC22A1 common genes common pathways GO:0006811| ion transport SLC22A1;SLC36A2 12562:[DB00260 DB06681] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB06681|Belatacept CD86;CD80 common genes common pathways 12563:[DB00260 DB01535] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;DDC 12564:[DB00260 DB00280] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0035690| cellular response to drug DDC;KCNH2 GO:0006811| ion transport KCND3;SCN5A;KCNH2;KCND2;SLC22A2;SLC22A1;SLC36A2 12565:[DB00260 DB01381] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0006811| ion transport GABRA1;GABRG2;GLRA1;SLC36A2;GABRB2 12566:[DB00260 DB01208] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0006811| ion transport SLC22A5;SLC36A2 12567:[DB00260 DB01283] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways 12568:[DB00260 DB01166] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC 12569:[DB00260 DB05311] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05311|Ecallantide KLKB1 common genes common pathways 12570:[DB00260 DB01241] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:0006811| ion transport SLCO1B1;SLC36A2 12571:[DB00260 DB00778] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways 12572:[DB00260 DB05465] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB05465|Tandutinib FLT3;PDGFD common genes common pathways 12573:[DB00260 DB00181] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways GO:0006811| ion transport SLC36A2;SLC22A8 GO:0009636| response to toxin DDC;SLC22A8 12574:[DB00260 DB04839] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways 12575:[DB00260 DB01276] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01276|Exenatide GLP1R;ALB common genes common pathways 12576:[DB00260 DB01949] DB00260|Cycloserine ddlA;DDC;SLC36A2 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 12577:[DB04998 DB07543] DB04998|AGRO100 IKBKG DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 12578:[DB04998 DB11730] DB04998|AGRO100 IKBKG DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0009615| response to virus CDK6;IKBKG 12579:[DB04998 DB00413] DB04998|AGRO100 IKBKG DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B;DRD4 12580:[DB04998 DB01224] DB04998|AGRO100 IKBKG DB01224|Quetiapine HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP3A4;CYP2C19;CYP2D6;ABCB1 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0006954| inflammatory response IKBKG;HRH1 GO:0016032| viral reproduction IKBKG;HTR2A GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG 12581:[DB04998 DB06605] DB04998|AGRO100 IKBKG DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways 12582:[DB04998 DB01179] DB04998|AGRO100 IKBKG DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 12583:[DB04998 DB05127] DB04998|AGRO100 IKBKG DB05127|ANA971 TLR7 common genes common pathways GO:0045087| innate immune response TLR7;IKBKG GO:0006954| inflammatory response IKBKG;TLR7 GO:0006955| immune response IKBKG;TLR7 12584:[DB04998 DB01148] DB04998|AGRO100 IKBKG DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 12585:[DB04998 DB01594] DB04998|AGRO100 IKBKG DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG 12586:[DB04998 DB00645] DB04998|AGRO100 IKBKG DB00645|Dyclonine SCN10A common genes common pathways 12587:[DB04998 DB06725] DB04998|AGRO100 IKBKG DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 12588:[DB04998 DB04863] DB04998|AGRO100 IKBKG DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction IKBKG;ITGB3 12589:[DB04998 DB00232] DB04998|AGRO100 IKBKG DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways 12590:[DB04998 DB01580] DB04998|AGRO100 IKBKG DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 12591:[DB04998 DB00196] DB04998|AGRO100 IKBKG DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways GO:0006955| immune response CYP11B1;IKBKG 12592:[DB04998 DB02789] DB04998|AGRO100 IKBKG DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 12593:[DB04998 DB08911] DB04998|AGRO100 IKBKG DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;MAP2K2;MAP2K1 12594:[DB04998 DB00087] DB04998|AGRO100 IKBKG DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;FCGR1A GO:0045087| innate immune response IKBKG;FCGR1A;C1R;C1QB;C1QA;C1QC GO:0006955| immune response C1QC;FCGR2C;FCGR3A;FCGR1A;IKBKG;FCGR2B;FCGR3B;C1R GO:0016032| viral reproduction FCGR2B;IKBKG GO:0006954| inflammatory response FCGR2B;IKBKG 12595:[DB04998 DB01415] DB04998|AGRO100 IKBKG DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 12596:[DB04998 DB06803] DB04998|AGRO100 IKBKG DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways 12597:[DB04998 DB00175] DB04998|AGRO100 IKBKG DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes common pathways 12598:[DB04998 DB00940] DB04998|AGRO100 IKBKG DB00940|Methantheline CHRM1;HRH2 common genes common pathways GO:0006955| immune response HRH2;IKBKG 12599:[DB04998 DB09422] DB04998|AGRO100 IKBKG DB09422|Soybean oil PPARA common genes common pathways GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PPARA 12600:[DB04998 DB00098] DB04998|AGRO100 IKBKG DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;ITGAV GO:0045087| innate immune response MR1;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD4;IKBKG GO:0016032| viral reproduction ITGB1;ITGAV;CD4;CD86;IKBKG;ITGB3;FCGR2B GO:0006955| immune response FCGR2B;MR1;CD86;IKBKG;CD1A;CD4 GO:0006954| inflammatory response FCGR2B;IKBKG;ITGAL GO:0050852| T cell receptor signaling pathway CD4;IKBKG 12601:[DB04998 DB00816] DB04998|AGRO100 IKBKG DB00816|Orciprenaline ADRB2 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 12602:[DB04998 DB00543] DB04998|AGRO100 IKBKG DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity DRD4;ADRA2B;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0009615| response to virus CHRM2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 GO:1901215| IKBKG;GABRB2;GABRB3 GO:0006954| inflammatory response ORM1;IKBKG;HRH1;HRH4 GO:0016032| viral reproduction HTR2A;IKBKG 12603:[DB04998 DB00936] DB04998|AGRO100 IKBKG DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 12604:[DB04998 DB01165] DB04998|AGRO100 IKBKG DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 12605:[DB04998 DB00671] DB04998|AGRO100 IKBKG DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 12606:[DB04998 DB03410] DB04998|AGRO100 IKBKG DB03410|4-hydroxycoumarin CYP3A4 common genes common pathways 12607:[DB04998 DB06685] DB04998|AGRO100 IKBKG DB06685|Laquinimod CYP3A4 common genes common pathways 12608:[DB04998 DB01618] DB04998|AGRO100 IKBKG DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A 12609:[DB04998 DB05111] DB04998|AGRO100 IKBKG DB05111|Fontolizumab IFNG common genes common pathways GO:0006915| apoptotic process IFNG;IKBKG GO:0006955| immune response IFNG;IKBKG GO:0009615| response to virus IFNG;IKBKG 12610:[DB04998 DB01023] DB04998|AGRO100 IKBKG DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0006351| transcription, DNA-dependent NR3C2;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR3C2;IKBKG GO:0006915| apoptotic process IKBKG;PDE1B GO:0038095| IKBKG;CALM1 12611:[DB04998 DB01029] DB04998|AGRO100 IKBKG DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0038095| IKBKG;JUN GO:0006355| regulation of transcription, DNA-dependent IKBKG;JUN GO:0006954| inflammatory response IKBKG;PTGS1 GO:0006351| transcription, DNA-dependent JUN;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;JUN 12612:[DB04998 DB00681] DB04998|AGRO100 IKBKG DB00681|Amphotericin B CYP3A4 common genes common pathways 12613:[DB04998 DB00866] DB04998|AGRO100 IKBKG DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination IKBKG;ADRB2 12614:[DB04998 DB06233] DB04998|AGRO100 IKBKG DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0043276| anoikis MTOR;IKBKG 12615:[DB04998 DB00843] DB04998|AGRO100 IKBKG DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A 12616:[DB04998 DB00987] DB04998|AGRO100 IKBKG DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0016579| protein deubiquitination POLB;IKBKG GO:0006915| apoptotic process IKBKG;POLB GO:0006954| inflammatory response POLB;IKBKG GO:0006974| response to DNA damage stimulus POLB;IKBKG 12617:[DB04998 DB05258] DB04998|AGRO100 IKBKG DB05258|Natural alpha interferon IFNAR1 common genes common pathways GO:0009615| response to virus IKBKG;IFNAR1 12618:[DB04998 DB08864] DB04998|AGRO100 IKBKG DB08864|Rilpivirine pol;NR1I2;CYP3A4;CYP2C19;CYP2B6;CYP2D6;ALB;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG 12619:[DB04998 DB14011] DB04998|AGRO100 IKBKG DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B;IKBKG GO:0006915| apoptotic process IKBKG;VDAC1;GPX1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG GO:0006955| immune response CNR2;OPRD1;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG;VDAC1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;PLA2G1B;CAT GO:0006954| inflammatory response TRPV1;IKBKG;ALOX15;IDO1;PTGS1;ALOX5;PTGS2;CNR2 GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IKBKG;PPARG GO:0009615| response to virus IKBKG;CYP1A1 GO:0045087| innate immune response IKBKG;PPARG 12620:[DB04998 DB09160] DB04998|AGRO100 IKBKG DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways 12621:[DB04998 DB08877] DB04998|AGRO100 IKBKG DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0045087| innate immune response JAK2;JAK1;IKBKG GO:0006915| apoptotic process JAK2;IKBKG 12622:[DB04998 DB11641] DB04998|AGRO100 IKBKG DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 12623:[DB04998 DB01211] DB04998|AGRO100 IKBKG DB01211|Clarithromycin rplJ;KCNH2;SLCO1B1;SLCO1B3;CYP3A4;CYP3A5;CYP2C19;CYP3A7;SLC22A7;ABCB1;ABCB11 common genes common pathways 12624:[DB04998 DB00292] DB04998|AGRO100 IKBKG DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006955| immune response CYP11B1;IKBKG GO:1901215| IKBKG;GABRB2;GABRB3 12625:[DB04998 DB01218] DB04998|AGRO100 IKBKG DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways 12626:[DB04998 DB01099] DB04998|AGRO100 IKBKG DB01099|Flucytosine DNMT1 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;DNMT1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;DNMT1 12627:[DB04998 DB01204] DB04998|AGRO100 IKBKG DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 12628:[DB04998 DB06267] DB04998|AGRO100 IKBKG DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways 12629:[DB04998 DB06660] DB04998|AGRO100 IKBKG DB06660|Saredutant TACR2 common genes common pathways 12630:[DB04998 DB09090] DB04998|AGRO100 IKBKG DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways 12631:[DB04998 DB12836] DB04998|AGRO100 IKBKG DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways GO:0006955| immune response IKBKG;PTGER4 GO:0007254| JNK cascade IKBKG;PTGER4 12632:[DB04998 DB00139] DB04998|AGRO100 IKBKG DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways 12633:[DB04998 DB00736] DB04998|AGRO100 IKBKG DB00736|Esomeprazole ATP4A;CYP2C19;CYP3A4 common genes common pathways 12634:[DB04998 DB01198] DB04998|AGRO100 IKBKG DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0006954| inflammatory response PTGS1;IKBKG GO:0006915| apoptotic process IKBKG;TSPO 12635:[DB04998 DB00854] DB04998|AGRO100 IKBKG DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1;OPRD1 12636:[DB04998 DB00623] DB04998|AGRO100 IKBKG DB00623|Fluphenazine DRD2;DRD1;CALM1;AR;HTR2A;HTR2C;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0006351| transcription, DNA-dependent AR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;AR GO:0038095| CALM1;IKBKG GO:0016579| protein deubiquitination AR;IKBKG 12637:[DB04998 DB14050] DB04998|AGRO100 IKBKG DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0006954| inflammatory response IKBKG;TRPV1 12638:[DB04998 DB00622] DB04998|AGRO100 IKBKG DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 GO:0038095| CALM1;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A;PDE1B 12639:[DB04998 DB05785] DB04998|AGRO100 IKBKG DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0038095| IKBKG;JUN GO:0006355| regulation of transcription, DNA-dependent IKBKG;RARB;RARG;RARA;JUN GO:0006351| transcription, DNA-dependent RARB;IKBKG;JUN;RARA;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter JUN;RARA;RARG;RARB;IKBKG 12640:[DB04998 DB00119] DB04998|AGRO100 IKBKG DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways 12641:[DB04998 DB01232] DB04998|AGRO100 IKBKG DB01232|Saquinavir pol;CYP3A7;CYP3A5;CYP3A4;CYP11A1;CYP2C8;CYP2D6;ORM1;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;ABCC1;ABCC2;SLCO2B1;ABCB11 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 12642:[DB04998 DB11201] DB04998|AGRO100 IKBKG DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 12643:[DB04998 DB00370] DB04998|AGRO100 IKBKG DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3;ADRB2 GO:0016032| viral reproduction IKBKG;HTR2A GO:0006955| immune response OPRK1;IKBKG GO:0006954| inflammatory response HRH1;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A GO:0016579| protein deubiquitination ADRB2;IKBKG 12644:[DB04998 DB01118] DB04998|AGRO100 IKBKG DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes common pathways GO:0045087| innate immune response PPARG;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;THRB;PPARG;THRA GO:0006351| transcription, DNA-dependent THRB;IKBKG;THRA;PPARG GO:0006355| regulation of transcription, DNA-dependent THRB;IKBKG;THRA;PPARG 12645:[DB04998 DB00392] DB04998|AGRO100 IKBKG DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 12646:[DB04998 DB00775] DB04998|AGRO100 IKBKG DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction IKBKG;ITGB3 12647:[DB04998 DB00768] DB04998|AGRO100 IKBKG DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0006954| inflammatory response IKBKG;S100A12;HRH1 GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A12;IKBKG GO:0045087| innate immune response S100A12;S100B;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;S100B;S100A13;S100A12 12648:[DB04998 DB00483] DB04998|AGRO100 IKBKG DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 12649:[DB04998 DB00300] DB04998|AGRO100 IKBKG DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NME2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NME2;IKBKG GO:0006351| transcription, DNA-dependent NME2;IKBKG 12650:[DB04998 DB00416] DB04998|AGRO100 IKBKG DB00416|Metocurine Iodide CHRNA2 common genes common pathways 12651:[DB04998 DB01036] DB04998|AGRO100 IKBKG DB01036|Tolterodine CHRM3;CHRM2;CHRM5;CHRM1;CHRM4;CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 12652:[DB04998 DB06506] DB04998|AGRO100 IKBKG DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways 12653:[DB04998 DB00960] DB04998|AGRO100 IKBKG DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 12654:[DB04998 DB14568] DB04998|AGRO100 IKBKG DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways 12655:[DB04998 DB09273] DB04998|AGRO100 IKBKG DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0006954| inflammatory response IKBKG;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ADORA2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0006915| apoptotic process IKBKG;ADORA2A 12656:[DB04998 DB00290] DB04998|AGRO100 IKBKG DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0006974| response to DNA damage stimulus LIG1;IKBKG;LIG3 12657:[DB04998 DB00732] DB04998|AGRO100 IKBKG DB00732|Atracurium besylate CHRNA2 common genes common pathways 12658:[DB04998 DB14597] DB04998|AGRO100 IKBKG DB14597|Lanadelumab KLKB1 common genes common pathways GO:0006954| inflammatory response KLKB1;IKBKG 12659:[DB04998 DB00945] DB04998|AGRO100 IKBKG DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0016579| protein deubiquitination IKBKG;NFKBIA;TP53 GO:0006915| apoptotic process TP53;RPS6KA3;IKBKG;NFKBIA;NFKB1 GO:0000187| activation of MAPK activity PRKAA1;IKBKG GO:0038095| IKBKB;NFKB1;NFKBIA;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKB;NFKB1;NFKB2;IKBKG;NFKBIA GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;IKBKB GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKB;IKBKG GO:0070423| nucleotide-binding oligomerization domain containing signaling pathway IKBKB;IKBKG GO:0016239| positive regulation of macroautophagy IKBKG;PRKAA2 GO:0006954| inflammatory response IKBKG;NFKB2;NFKB1;PTGS1;IKBKB;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB2;NFKBIA;IKBKG;IKBKB;NFKB1 GO:0016032| viral reproduction NFKBIA;IKBKG;TP53 GO:0050852| T cell receptor signaling pathway IKBKB;NFKB1;IKBKG;NFKBIA GO:0006355| regulation of transcription, DNA-dependent IKBKG;PRKAA1;NFKB2;PRKAA2;TP53;NFKB1 GO:0045087| innate immune response NFKB2;IKBKG;IKBKB;NFKB1 GO:0006974| response to DNA damage stimulus TP53;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKB;IKBKG GO:0009615| response to virus IKBKB;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;IKBKB;NFKBIA;IKBKG;TP53;NFKB2;RPS6KA3 GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKB;NFKB1;NFKBIA;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;IKBKB GO:0051403| stress-activated MAPK cascade NFKB1;IKBKB;IKBKG GO:0006351| transcription, DNA-dependent NFKB1;PRKAA1;IKBKG;TP53;NFKB2;PRKAA2 GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKG;IKBKB 12660:[DB04998 DB06739] DB04998|AGRO100 IKBKG DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0006954| inflammatory response TBXA2R;PTGS1;IKBKG 12661:[DB04998 DB00296] DB04998|AGRO100 IKBKG DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways 12662:[DB04998 DB07670] DB04998|AGRO100 IKBKG DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways 12663:[DB04998 DB01087] DB04998|AGRO100 IKBKG DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 GO:0016032| viral reproduction IKBKG;KRT7 12664:[DB04998 DB11753] DB04998|AGRO100 IKBKG DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways 12665:[DB04998 DB01124] DB04998|AGRO100 IKBKG DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways 12666:[DB04998 DB00997] DB04998|AGRO100 IKBKG DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes common pathways GO:0006974| response to DNA damage stimulus IKBKG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A;NOS1 12667:[DB04998 DB00266] DB04998|AGRO100 IKBKG DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways 12668:[DB04998 DB00800] DB04998|AGRO100 IKBKG DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B 12669:[DB04998 DB05676] DB04998|AGRO100 IKBKG DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IKBKG GO:0006954| inflammatory response IKBKG;TNF GO:0006955| immune response IL2;IKBKG;TNF;IFNG GO:0050852| T cell receptor signaling pathway PDE4B;IKBKG;PDE4D GO:0009615| response to virus IFNG;IKBKG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;IL2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNF GO:0006915| apoptotic process IFNG;IKBKG GO:0000187| activation of MAPK activity TNF;IKBKG GO:0007254| JNK cascade TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG 12670:[DB04998 DB06694] DB04998|AGRO100 IKBKG DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B 12671:[DB04998 DB11587] DB04998|AGRO100 IKBKG DB11587|Etafedrine ADRB2 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 12672:[DB04998 DB06469] DB04998|AGRO100 IKBKG DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways 12673:[DB04998 DB06737] DB04998|AGRO100 IKBKG DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways GO:0006954| inflammatory response PTGS1;IKBKG 12674:[DB04998 DB14583] DB04998|AGRO100 IKBKG DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0016579| protein deubiquitination AR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PGR;NR3C1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;NR3C1;IKBKG;PGR GO:0006355| regulation of transcription, DNA-dependent AR;NR3C1;PGR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR 12675:[DB04998 DB08867] DB04998|AGRO100 IKBKG DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0016579| protein deubiquitination AR;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG;AR;NR3C1 GO:0006351| transcription, DNA-dependent AR;NR3C1;PGR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006954| inflammatory response IKBKG;ORM1 GO:0006355| regulation of transcription, DNA-dependent AR;NR3C1;IKBKG;PGR 12676:[DB04998 DB01251] DB04998|AGRO100 IKBKG DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways 12677:[DB04998 DB09235] DB04998|AGRO100 IKBKG DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways 12678:[DB04998 DB04725] DB04998|AGRO100 IKBKG DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0006954| inflammatory response IKBKG;PLA2G2E;ALOX5;PTGS2 12679:[DB04998 DB00153] DB04998|AGRO100 IKBKG DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent VDR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;IKBKG GO:0006351| transcription, DNA-dependent VDR;IKBKG 12680:[DB04998 DB00358] DB04998|AGRO100 IKBKG DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0006915| apoptotic process ADORA2A;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ADORA2A GO:0006954| inflammatory response IKBKG;ADORA2A 12681:[DB04998 DB00770] DB04998|AGRO100 IKBKG DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0006955| immune response IKBKG;PTGDR2 12682:[DB04998 DB09256] DB04998|AGRO100 IKBKG DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways 12683:[DB04998 DB09229] DB04998|AGRO100 IKBKG DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0006954| inflammatory response ORM1;IKBKG 12684:[DB04998 DB09078] DB04998|AGRO100 IKBKG DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0006915| apoptotic process FGFR3;IKBKG;FGFR2 GO:0000187| activation of MAPK activity IKBKG;KIT GO:0006351| transcription, DNA-dependent IKBKG;FGFR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;FGFR2 GO:0006355| regulation of transcription, DNA-dependent IKBKG;FGFR1 GO:0006954| inflammatory response KIT;IKBKG GO:0016032| viral reproduction KDR;IKBKG GO:0016239| positive regulation of macroautophagy KDR;IKBKG 12685:[DB04998 DB00417] DB04998|AGRO100 IKBKG DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 12686:[DB04998 DB11691] DB04998|AGRO100 IKBKG DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0006955| immune response IKBKG;OPRK1;OPRD1 12687:[DB04998 DB06311] DB04998|AGRO100 IKBKG DB06311|Darapladib PLA2G4A common genes common pathways 12688:[DB04998 DB00701] DB04998|AGRO100 IKBKG DB00701|Amprenavir pol;CYP3A4;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A5;ABCB1;ABCC1;SLCO1B1 common genes common pathways 12689:[DB04998 DB00738] DB04998|AGRO100 IKBKG DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 12690:[DB04998 DB00882] DB04998|AGRO100 IKBKG DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0006351| transcription, DNA-dependent IKBKG;ESR1 GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ESR1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR1 12691:[DB04998 DB01248] DB04998|AGRO100 IKBKG DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0006915| apoptotic process IKBKG;BCL2 GO:0006974| response to DNA damage stimulus BCL2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG 12692:[DB04998 DB00269] DB04998|AGRO100 IKBKG DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG GO:0006351| transcription, DNA-dependent ESR1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG GO:0016579| protein deubiquitination ESR1;IKBKG 12693:[DB04998 DB00497] DB04998|AGRO100 IKBKG DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0006955| immune response IKBKG;OPRK1;OPRD1 12694:[DB04998 DB05420] DB04998|AGRO100 IKBKG DB05420|Gallium maltolate RRM1 common genes common pathways 12695:[DB04998 DB08903] DB04998|AGRO100 IKBKG DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways 12696:[DB04998 DB08931] DB04998|AGRO100 IKBKG DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG GO:0006954| inflammatory response ORM1;IKBKG 12697:[DB04998 DB01058] DB04998|AGRO100 IKBKG DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 12698:[DB04998 DB00332] DB04998|AGRO100 IKBKG DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 12699:[DB04998 DB05025] DB04998|AGRO100 IKBKG DB05025|Arimoclomol SOD1 common genes common pathways GO:0000187| activation of MAPK activity SOD1;IKBKG 12700:[DB04998 DB06824] DB04998|AGRO100 IKBKG DB06824|Triethylenetetramine GPC1 common genes common pathways 12701:[DB04998 DB06780] DB04998|AGRO100 IKBKG DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR3C2;IKBKG GO:0006351| transcription, DNA-dependent NR3C2;IKBKG 12702:[DB04998 DB00991] DB04998|AGRO100 IKBKG DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 12703:[DB04998 DB02750] DB04998|AGRO100 IKBKG DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 12704:[DB04998 DB11638] DB04998|AGRO100 IKBKG DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0006915| apoptotic process CYCS;GAPDH;LGALS1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity NPM1;IKBKG GO:0016032| viral reproduction VIM;ZYX;IKBKG;NPM1;HSPA8;HNRNPK;PPIA GO:0006355| regulation of transcription, DNA-dependent HSPA8;HNRNPK;EEF1A1;DDX5;ENO1;SF1;SFPQ;IKBKG;HP1BP3;HNRNPD;KHSRP GO:0045087| innate immune response IKBKG;SFPQ GO:0006974| response to DNA damage stimulus FTO;SFPQ;IKBKG GO:0009615| response to virus HSPB1;IKBKG;ENO1;CFL1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SFPQ;IKBKG;HNRNPK;NPM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;FLNA;LGALS1 GO:0006351| transcription, DNA-dependent HNRNPD;KHSRP;HSPA8;HNRNPK;EEF1A1;DDX5;SF1;ENO1;IKBKG;SFPQ 12705:[DB04998 DB06216] DB04998|AGRO100 IKBKG DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3;ADRB2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0006955| immune response IKBKG;HRH2 GO:0006954| inflammatory response HRH1;IKBKG 12706:[DB04998 DB07374] DB04998|AGRO100 IKBKG DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;RPL23 12707:[DB04998 DB14637] DB04998|AGRO100 IKBKG DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways 12708:[DB04998 DB00228] DB04998|AGRO100 IKBKG DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;IKBKG GO:1901215| IKBKG;GABRB2;GABRB3 12709:[DB04998 DB00663] DB04998|AGRO100 IKBKG DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 12710:[DB04998 DB00801] DB04998|AGRO100 IKBKG DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 12711:[DB04998 DB01282] DB04998|AGRO100 IKBKG DB01282|Carbetocin OXTR common genes common pathways 12712:[DB04998 DB00477] DB04998|AGRO100 IKBKG DB00477|Chlorpromazine DRD2;DRD1;HTR1A;HTR2A;ADRA1A;ADRA1B;HRH1;KCNH2;DRD1;DRD5;DRD3;DRD4;DRD5;HTR2C;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM3;SMPD1;CALM1;ORM1;ORM2;HTR6;HTR7;HRH4;CYP2D6;CYP1A2;CYP2E1;CYP3A4;BCHE;ALB;ABCB1;ABCB11 common genes common pathways GO:0038095| CALM1;IKBKG GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A GO:0006954| inflammatory response IKBKG;ORM1;HRH1;HRH4 GO:0016032| viral reproduction HTR2A;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3 12713:[DB04998 DB00226] DB04998|AGRO100 IKBKG DB00226|Guanadrel SLC6A2 common genes common pathways 12714:[DB04998 DB01373] DB04998|AGRO100 IKBKG DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0006915| apoptotic process IKBKG;COMP;PDCD6;S100A8;S100A9 GO:0038095| CALM1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A8;S100A9;IKBKG GO:0006954| inflammatory response S100A9;S100A8;IKBKG GO:0045087| innate immune response IKBKG;S100A8;S100A9;S100B GO:0045944| positive regulation of transcription from RNA polymerase II promoter BMP4;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ATP2C1;S100B;S100A13 12715:[DB04998 DB01321] DB04998|AGRO100 IKBKG DB01321|Josamycin rplD;CYP3A4 common genes common pathways 12716:[DB04998 DB00631] DB04998|AGRO100 IKBKG DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0016032| viral reproduction IKBKG;POLA1 12717:[DB04998 DB09209] DB04998|AGRO100 IKBKG DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0006955| immune response OPRD1;OPRK1;IKBKG 12718:[DB04998 DB00114] DB04998|AGRO100 IKBKG DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity CTH;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;CTH GO:0009615| response to virus ODC1;IKBKG GO:0006915| apoptotic process IKBKG;SGPL1 12719:[DB04998 DB11091] DB04998|AGRO100 IKBKG DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IKBKG GO:0006915| apoptotic process GPX1;IKBKG 12720:[DB04998 DB13179] DB04998|AGRO100 IKBKG DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 12721:[DB04998 DB01435] DB04998|AGRO100 IKBKG DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 12722:[DB04998 DB11640] DB04998|AGRO100 IKBKG DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways 12723:[DB04998 DB00898] DB04998|AGRO100 IKBKG DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 GO:0016032| viral reproduction IKBKG;VCAM1 GO:1901215| GABRB2;IKBKG;GABRB3 GO:0000187| activation of MAPK activity CHRNA7;IKBKG 12724:[DB04998 DB00197] DB04998|AGRO100 IKBKG DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0045087| innate immune response PPARG;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;SERPINE1;PPARG;IKBKG;ESRRA;ESRRG GO:0006351| transcription, DNA-dependent PPARA;PPARD;IKBKG;ESRRA;ESRRG;PPARG GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent ESRRA;IKBKG;ESRRG;PPARG;PPARA;PPARD GO:0006915| apoptotic process IKBKG;PPARD 12725:[DB04998 DB01186] DB04998|AGRO100 IKBKG DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;IKBKG;DRD2 GO:0000187| activation of MAPK activity IKBKG;ADRA2B;DRD4 GO:0006915| apoptotic process IKBKG;ADRA1A 12726:[DB04998 DB00795] DB04998|AGRO100 IKBKG DB00795|Sulfasalazine ALOX5;PTGS2;PTGS1;PPARG;CHUK;IKBKB;SLC7A11;ACAT1;TBXAS1;PLA2G1B;ABCG2;ABCC2;SLC46A1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0038095| IKBKB;CHUK;IKBKG GO:0000187| activation of MAPK activity PLA2G1B;IKBKG GO:0035666| TRIF-dependent toll-like receptor signaling pathway CHUK;IKBKB;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;IKBKB;CHUK GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKB;CHUK;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;IKBKB;CHUK GO:0006954| inflammatory response IKBKG;IKBKB;PTGS2;ALOX5;PTGS1;CHUK GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKB;CHUK;PLA2G1B;IKBKG GO:0006955| immune response IKBKG;CHUK GO:0070423| nucleotide-binding oligomerization domain containing signaling pathway CHUK;IKBKB;IKBKG GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKG;CHUK;IKBKB GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKB;CHUK;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CHUK;IKBKB;IKBKG GO:0051403| stress-activated MAPK cascade IKBKG;CHUK;IKBKB GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0009615| response to virus CHUK;IKBKB;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;IKBKB;IKBKG;PLA2G1B;PPARG GO:0045087| innate immune response CHUK;IKBKB;IKBKG;PPARG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent CHUK;IKBKB;IKBKG 12727:[DB04998 DB11569] DB04998|AGRO100 IKBKG DB11569|Ixekizumab IL17A common genes common pathways GO:0006915| apoptotic process IL17A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;IL17A GO:0006954| inflammatory response IL17A;IKBKG GO:0006955| immune response IKBKG;IL17A 12728:[DB04998 DB01032] DB04998|AGRO100 IKBKG DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0016032| viral reproduction SLC10A1;IKBKG 12729:[DB04998 DB01130] DB04998|AGRO100 IKBKG DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006915| apoptotic process NR3C1;IKBKG 12730:[DB04998 DB06634] DB04998|AGRO100 IKBKG DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0006954| inflammatory response TACR1;IKBKG 12731:[DB04998 DB00628] DB04998|AGRO100 IKBKG DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0006915| apoptotic process TSPO;IKBKG GO:1901215| IKBKG;GABRB2;GABRB3 12732:[DB04998 DB09089] DB04998|AGRO100 IKBKG DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 GO:0050852| T cell receptor signaling pathway CACNB3;IKBKG 12733:[DB04998 DB09570] DB04998|AGRO100 IKBKG DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways 12734:[DB04998 DB08815] DB04998|AGRO100 IKBKG DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A 12735:[DB04998 DB00400] DB04998|AGRO100 IKBKG DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways 12736:[DB04998 DB01629] DB04998|AGRO100 IKBKG DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0000187| activation of MAPK activity SOD1;IKBKG 12737:[DB04998 DB12478] DB04998|AGRO100 IKBKG DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 12738:[DB04998 DB00468] DB04998|AGRO100 IKBKG DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 12739:[DB04998 DB00208] DB04998|AGRO100 IKBKG DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 12740:[DB04998 DB01021] DB04998|AGRO100 IKBKG DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways 12741:[DB04998 DB00824] DB04998|AGRO100 IKBKG DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0050852| T cell receptor signaling pathway IKBKG;PDE4B GO:0006355| regulation of transcription, DNA-dependent ADORA2A;IKBKG GO:0006954| inflammatory response ADORA1;ADORA3;ADORA2A;IKBKG GO:0006915| apoptotic process ADORA2A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADORA2B GO:0007254| JNK cascade ADORA2B;IKBKG 12742:[DB04998 DB11834] DB04998|AGRO100 IKBKG DB11834|Guselkumab IL23A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL23A;IKBKG GO:0045087| innate immune response IKBKG;IL23A GO:0006954| inflammatory response IL23A;IKBKG GO:0006955| immune response IL23A;IKBKG 12743:[DB04998 DB08906] DB04998|AGRO100 IKBKG DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG 12744:[DB04998 DB02546] DB04998|AGRO100 IKBKG DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;HDAC3;HDAC1;IKBKG GO:0006351| transcription, DNA-dependent HDAC6;HDAC3;HDAC2;HDAC8;HDAC1;IKBKG GO:0016032| viral reproduction IKBKG;HDAC1 GO:0006355| regulation of transcription, DNA-dependent HDAC6;HDAC8;HDAC2;HDAC3;HDAC1;IKBKG 12745:[DB04998 DB11124] DB04998|AGRO100 IKBKG DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B 12746:[DB04998 DB06587] DB04998|AGRO100 IKBKG DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways 12747:[DB04998 DB02209] DB04998|AGRO100 IKBKG DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0009615| response to virus ODC1;IKBKG 12748:[DB04998 DB09363] DB04998|AGRO100 IKBKG DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways 12749:[DB04998 DB00912] DB04998|AGRO100 IKBKG DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IKBKG GO:0045087| innate immune response PPARG;IKBKG GO:0006351| transcription, DNA-dependent PPARG;IKBKG 12750:[DB04998 DB14010] DB04998|AGRO100 IKBKG DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG 12751:[DB04998 DB01256] DB04998|AGRO100 IKBKG DB01256|Retapamulin rplC;CYP3A4 common genes common pathways 12752:[DB04998 DB14509] DB04998|AGRO100 IKBKG DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:1901215| IKBKG;GSK3B 12753:[DB04998 DB04836] DB04998|AGRO100 IKBKG DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways 12754:[DB04998 DB00211] DB04998|AGRO100 IKBKG DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 12755:[DB04998 DB08895] DB04998|AGRO100 IKBKG DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0006915| apoptotic process IKBKG;JAK2 GO:0006954| inflammatory response IKBKG;JAK3 GO:0045087| innate immune response IKBKG;JAK1;JAK2;TYK2;JAK3 12756:[DB04998 DB01324] DB04998|AGRO100 IKBKG DB01324|Polythiazide SLC12A3 common genes common pathways 12757:[DB04998 DB14539] DB04998|AGRO100 IKBKG DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006915| apoptotic process NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0045087| innate immune response ANXA1;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0006955| immune response CYP11B1;IKBKG GO:0006954| inflammatory response IKBKG;ANXA1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 12758:[DB04998 DB00863] DB04998|AGRO100 IKBKG DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0006955| immune response HRH2;IKBKG 12759:[DB04998 DB05885] DB04998|AGRO100 IKBKG DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways 12760:[DB04998 DB11127] DB04998|AGRO100 IKBKG DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0006915| apoptotic process IKBKG;GPX1 12761:[DB04998 DB09204] DB04998|AGRO100 IKBKG DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0006954| inflammatory response IKBKG;ORM1 GO:0006915| apoptotic process IKBKG;ADRA1A GO:0016579| protein deubiquitination ADRB2;IKBKG 12762:[DB04998 DB08826] DB04998|AGRO100 IKBKG DB08826|Deferiprone UGT1A6 common genes common pathways 12763:[DB04998 DB01205] DB04998|AGRO100 IKBKG DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 12764:[DB04998 DB09185] DB04998|AGRO100 IKBKG DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways 12765:[DB04998 DB00285] DB04998|AGRO100 IKBKG DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways 12766:[DB04998 DB06013] DB04998|AGRO100 IKBKG DB06013|Aldoxorubicin TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG 12767:[DB04998 DB14004] DB04998|AGRO100 IKBKG DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0045087| innate immune response IL23A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL23A;IKBKG GO:0006954| inflammatory response IL23A;IKBKG GO:0006955| immune response IKBKG;IL23A 12768:[DB04998 DB00708] DB04998|AGRO100 IKBKG DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0006955| immune response OPRD1;IKBKG;OPRK1 12769:[DB04998 DB09148] DB04998|AGRO100 IKBKG DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0006915| apoptotic process IKBKG;APP GO:0000187| activation of MAPK activity APP;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;IKBKG GO:0045087| innate immune response IKBKG;APP GO:1901215| IKBKG;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;APP 12770:[DB04998 DB00390] DB04998|AGRO100 IKBKG DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways 12771:[DB04998 DB00407] DB04998|AGRO100 IKBKG DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 12772:[DB04998 DB00822] DB04998|AGRO100 IKBKG DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways 12773:[DB04998 DB00966] DB04998|AGRO100 IKBKG DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IKBKG GO:0045087| innate immune response IKBKG;PPARG GO:0006351| transcription, DNA-dependent IKBKG;PPARG 12774:[DB04998 DB05014] DB04998|AGRO100 IKBKG DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0006351| transcription, DNA-dependent FGFR1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;FGFR1 GO:0016032| viral reproduction IKBKG;KDR GO:0016239| positive regulation of macroautophagy KDR;IKBKG GO:0006915| apoptotic process FGFR3;IKBKG 12775:[DB04998 DB09378] DB04998|AGRO100 IKBKG DB09378|Fluprednisolone CYP3A4 common genes common pathways 12776:[DB04998 DB12026] DB04998|AGRO100 IKBKG DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 12777:[DB04998 DB00215] DB04998|AGRO100 IKBKG DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 GO:0006915| apoptotic process IKBKG;ADRA1A 12778:[DB04998 DB00250] DB04998|AGRO100 IKBKG DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG 12779:[DB04998 DB00980] DB04998|AGRO100 IKBKG DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways 12780:[DB04998 DB00241] DB04998|AGRO100 IKBKG DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 GO:0000187| activation of MAPK activity IKBKG;CHRNA7 12781:[DB04998 DB00467] DB04998|AGRO100 IKBKG DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 12782:[DB04998 DB03336] DB04998|AGRO100 IKBKG DB03336|BIA COMT common genes common pathways 12783:[DB04998 DB12693] DB04998|AGRO100 IKBKG DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A 12784:[DB04998 DB09124] DB04998|AGRO100 IKBKG DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG GO:0006351| transcription, DNA-dependent PGR;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR 12785:[DB04998 DB00013] DB04998|AGRO100 IKBKG DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;IKBKG 12786:[DB04998 DB00206] DB04998|AGRO100 IKBKG DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0006915| apoptotic process BIRC5;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;BIRC5 GO:0006351| transcription, DNA-dependent BIRC5;IKBKG 12787:[DB04998 DB01222] DB04998|AGRO100 IKBKG DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006915| apoptotic process NR3C1;IKBKG 12788:[DB04998 DB06446] DB04998|AGRO100 IKBKG DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A 12789:[DB04998 DB09383] DB04998|AGRO100 IKBKG DB09383|Meprednisone CYP3A4;ALB common genes common pathways 12790:[DB04998 DB01403] DB04998|AGRO100 IKBKG DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3 GO:0016032| viral reproduction IKBKG;HTR2A GO:0006954| inflammatory response IKBKG;HRH1 GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B;DRD4 12791:[DB04998 DB14009] DB04998|AGRO100 IKBKG DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0045087| innate immune response PPARG;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;IKBKG GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;PLA2G1B;CAT GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;IDO1;IKBKG;ALOX15;TRPV1 GO:0006955| immune response IKBKG;OPRD1;CNR2 GO:0016032| viral reproduction HTR2A;IKBKG;VDAC1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG GO:0006915| apoptotic process IKBKG;VDAC1;GPX1 GO:0000187| activation of MAPK activity IKBKG;PLA2G1B;SOD1;CHRNA7 12792:[DB04998 DB08954] DB04998|AGRO100 IKBKG DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 12793:[DB04998 DB11338] DB04998|AGRO100 IKBKG DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CXCL10;IKBKG GO:0009615| response to virus IKBKG;CXCL10 GO:0006955| immune response CXCL10;IKBKG GO:0016032| viral reproduction IKBKG;VCAM1 GO:0006954| inflammatory response IKBKG;CXCL10 12794:[DB04998 DB00505] DB04998|AGRO100 IKBKG DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 12795:[DB04998 DB11635] DB04998|AGRO100 IKBKG DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0016032| viral reproduction SCARB1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;SEC14L2 GO:0006351| transcription, DNA-dependent IKBKG;SEC14L2 12796:[DB04998 DB00837] DB04998|AGRO100 IKBKG DB00837|Progabide GABBR1;GABRA1 common genes common pathways 12797:[DB04998 DB06785] DB04998|AGRO100 IKBKG DB06785|Ganirelix GNRHR common genes common pathways 12798:[DB04998 DB13620] DB04998|AGRO100 IKBKG DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways 12799:[DB04998 DB14071] DB04998|AGRO100 IKBKG DB14071|Desmethylsertraline ABCB1 common genes common pathways 12800:[DB04998 DB00381] DB04998|AGRO100 IKBKG DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 12801:[DB04998 DB01173] DB04998|AGRO100 IKBKG DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 12802:[DB04998 DB00915] DB04998|AGRO100 IKBKG DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 12803:[DB04998 DB00238] DB04998|AGRO100 IKBKG DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes common pathways 12804:[DB04998 DB00214] DB04998|AGRO100 IKBKG DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0006954| inflammatory response PTGS1;IKBKG 12805:[DB04998 DB11792] DB04998|AGRO100 IKBKG DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 12806:[DB04998 DB01120] DB04998|AGRO100 IKBKG DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;VEGFA 12807:[DB04998 DB00423] DB04998|AGRO100 IKBKG DB00423|Methocarbamol CA1 common genes common pathways 12808:[DB04998 DB06726] DB04998|AGRO100 IKBKG DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 12809:[DB04998 DB11477] DB04998|AGRO100 IKBKG DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B 12810:[DB04998 DB00244] DB04998|AGRO100 IKBKG DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;CHUK;IKBKB GO:0045087| innate immune response CHUK;IKBKB;IKBKG;PPARG GO:0009615| response to virus CHUK;IKBKB;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKB;CHUK;PPARG;IKBKG GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway CHUK;IKBKB;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKB;CHUK;IKBKG GO:0051403| stress-activated MAPK cascade CHUK;IKBKB;IKBKG GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKB;CHUK;IKBKG GO:0070423| nucleotide-binding oligomerization domain containing signaling pathway IKBKG;CHUK;IKBKB GO:0006955| immune response CHUK;IKBKG GO:0006954| inflammatory response IKBKB;PTGS2;PTGS1;ALOX5;CHUK;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;IKBKB;CHUK GO:0050852| T cell receptor signaling pathway IKBKG;CHUK;IKBKB GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKB;CHUK;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway CHUK;IKBKB;IKBKG GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKB;CHUK;IKBKG GO:0038095| CHUK;IKBKB;IKBKG 12811:[DB04998 DB11274] DB04998|AGRO100 IKBKG DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3 12812:[DB04998 DB00274] DB04998|AGRO100 IKBKG DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways 12813:[DB04998 DB01352] DB04998|AGRO100 IKBKG DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 12814:[DB04998 DB06468] DB04998|AGRO100 IKBKG DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;SLC9A1 12815:[DB04998 DB14185] DB04998|AGRO100 IKBKG DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity IKBKG;DRD4;ADRA2B GO:0006954| inflammatory response HRH1;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0009615| response to virus CHRM2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG 12816:[DB04998 DB01044] DB04998|AGRO100 IKBKG DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways 12817:[DB04998 DB00759] DB04998|AGRO100 IKBKG DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways GO:0045087| innate immune response PADI4;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PADI4 GO:0006355| regulation of transcription, DNA-dependent PADI4;IKBKG 12818:[DB04998 DB04894] DB04998|AGRO100 IKBKG DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0006954| inflammatory response TACR1;IKBKG 12819:[DB04998 DB01206] DB04998|AGRO100 IKBKG DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways 12820:[DB04998 DB12001] DB04998|AGRO100 IKBKG DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0009615| response to virus IKBKG;CDK6 12821:[DB04998 DB08953] DB04998|AGRO100 IKBKG DB08953|Indalpine CYP3A4 common genes common pathways 12822:[DB04998 DB01131] DB04998|AGRO100 IKBKG DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways 12823:[DB04998 DB00421] DB04998|AGRO100 IKBKG DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0050852| T cell receptor signaling pathway IKBKG;CACNB3 GO:0006355| regulation of transcription, DNA-dependent AR;NR3C1;PGR;IKBKG;NR3C2;NR1I2 GO:0006955| immune response IKBKG;CYP11B1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006351| transcription, DNA-dependent NR3C1;AR;NR1I2;PGR;IKBKG;NR3C2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR;NR1I2;AR;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 GO:0016579| protein deubiquitination IKBKG;AR 12824:[DB04998 DB00572] DB04998|AGRO100 IKBKG DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 12825:[DB04998 DB01045] DB04998|AGRO100 IKBKG DB01045|Rifampicin rpoB;rpoC;NR1I2;SLCO1B1;SLCO1A2;SLCO1B3;CYP51A1;ALB;SLCO2B1;CYP2C9;CYP1A2;CYP2C8;CYP3A4;CYP2B6;UGT1A1;CYP2C19;CYP2A6;CYP2E1;CYP3A43;CYP3A7;CYP4A11;CYP2D6;ABCB1;SLCO1B3;ABCC1;SLCO2B1;ABCB11;SLCO1A2;SLC22A7;SLCO1B1;ABCC5;ABCC2;ABCC3;SLC22A6;SLC22A8 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 12826:[DB04998 DB00415] DB04998|AGRO100 IKBKG DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways 12827:[DB04998 DB00312] DB04998|AGRO100 IKBKG DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2;GRIN1 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0000187| activation of MAPK activity IKBKG;CHRNA7 12828:[DB04998 DB00650] DB04998|AGRO100 IKBKG DB00650|Leucovorin SLC22A8 common genes common pathways 12829:[DB04998 DB08980] DB04998|AGRO100 IKBKG DB08980|Fendiline CYP3A4 common genes common pathways 12830:[DB04998 DB09183] DB04998|AGRO100 IKBKG DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways 12831:[DB04998 DB00111] DB04998|AGRO100 IKBKG DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response C1QA;C1QC;IKBKG;FCGR1A;C1R;C1QB GO:0006955| immune response C1R;FCGR2B;FCGR3B;FCGR1A;IKBKG;FCGR2C;FCGR3A;IL2RA;C1QC GO:0016032| viral reproduction IKBKG;FCGR2B;IL2RB GO:0006954| inflammatory response IKBKG;FCGR2B;IL2RA GO:0006915| apoptotic process IL2RA;IKBKG 12832:[DB04998 DB01030] DB04998|AGRO100 IKBKG DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0016032| viral reproduction IKBKG;TOP1 12833:[DB04998 DB13933] DB04998|AGRO100 IKBKG DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways 12834:[DB04998 DB01466] DB04998|AGRO100 IKBKG DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways 12835:[DB04998 DB00568] DB04998|AGRO100 IKBKG DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0009615| response to virus CHRM2;CYP1A1;IKBKG GO:0006954| inflammatory response IKBKG;HRH1 12836:[DB04998 DB01053] DB04998|AGRO100 IKBKG DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways 12837:[DB04998 DB03907] DB04998|AGRO100 IKBKG DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways 12838:[DB04998 DB01085] DB04998|AGRO100 IKBKG DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 12839:[DB04998 DB00227] DB04998|AGRO100 IKBKG DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent HDAC2;IKBKG GO:0006954| inflammatory response ITGAL;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;IKBKG 12840:[DB04998 DB01645] DB04998|AGRO100 IKBKG DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRB;ESR2;ESRRA;IKBKG;NR1I2;TOP2A;NCOA2;GPER1;NCOA1;ESR1;AKT1 GO:0045087| innate immune response GPER1;IKBKG;PTK2B GO:0006974| response to DNA damage stimulus TOP2A;IKBKG;AKT1 GO:0006351| transcription, DNA-dependent NCOA1;ESR1;NCOA2;NR1I2;ESR2;ESRRB;ESRRA;IKBKG GO:0006954| inflammatory response IKBKG;AKT1;GPER1 GO:0043276| anoikis IKBKG;AKT1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA1;ESRRB;ESR2;IKBKG;ESRRA;NR1I2;NCOA2 GO:1901215| AKT1;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade AKT1;IKBKG GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0006915| apoptotic process IKBKG;PTK2B;AKT1;GPER1 12841:[DB04998 DB00883] DB04998|AGRO100 IKBKG DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways 12842:[DB04998 DB01033] DB04998|AGRO100 IKBKG DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways 12843:[DB04998 DB06372] DB04998|AGRO100 IKBKG DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;IL1B;IL1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;IKBKG GO:0006954| inflammatory response IL1A;IL1RN;IKBKG;IL1B GO:0006955| immune response IL1A;IL1RN;IL1B;IKBKG GO:0006915| apoptotic process IL1A;IL1B;IKBKG GO:0000187| activation of MAPK activity IKBKG;IL1B 12844:[DB04998 DB08814] DB04998|AGRO100 IKBKG DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;NFKB1 GO:0006915| apoptotic process IKBKG;NFKB1 GO:0038095| NFKB1;IKBKG GO:0045087| innate immune response NFKB1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NFKB1 GO:0006351| transcription, DNA-dependent IKBKG;NFKB1 GO:0051403| stress-activated MAPK cascade NFKB1;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway NFKB1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;IKBKG GO:0006954| inflammatory response IKBKG;PTGS1;NFKB1 GO:0050852| T cell receptor signaling pathway NFKB1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NFKB1 12845:[DB04998 DB00365] DB04998|AGRO100 IKBKG DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes common pathways 12846:[DB04998 DB11619] DB04998|AGRO100 IKBKG DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent NR3C1;ESR1;AR;PGR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR;ESR1;NR3C1;AR GO:0006355| regulation of transcription, DNA-dependent AR;NR3C1;ESR1;PGR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 GO:0016579| protein deubiquitination IKBKG;ESR1;AR 12847:[DB04998 DB09272] DB04998|AGRO100 IKBKG DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0006955| immune response OPRD1;IKBKG;OPRK1 12848:[DB04998 DB04871] DB04998|AGRO100 IKBKG DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 12849:[DB04998 DB00294] DB04998|AGRO100 IKBKG DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;PGR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG;PGR GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR;ESR1 GO:0016579| protein deubiquitination IKBKG;ESR1 12850:[DB04998 DB00657] DB04998|AGRO100 IKBKG DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 12851:[DB04998 DB08844] DB04998|AGRO100 IKBKG DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways 12852:[DB04998 DB01182] DB04998|AGRO100 IKBKG DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination IKBKG;ADRB2 12853:[DB04998 DB01104] DB04998|AGRO100 IKBKG DB01104|Sertraline SLC6A4;SLC6A3;PGRMC1;SIGMAR1;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP2B6;MAOB;MAOA;CYP2B;ALB;ABCB1 common genes common pathways 12854:[DB04998 DB00810] DB04998|AGRO100 IKBKG DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways 12855:[DB04998 DB01018] DB04998|AGRO100 IKBKG DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways GO:0000187| activation of MAPK activity ADRA2B;IKBKG 12856:[DB04998 DB05361] DB04998|AGRO100 IKBKG DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade F2R;IKBKG GO:0006954| inflammatory response F2R;IKBKG 12857:[DB04998 DB01409] DB04998|AGRO100 IKBKG DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 12858:[DB04998 DB04833] DB04998|AGRO100 IKBKG DB04833|Methaqualone CYP3A4 common genes common pathways 12859:[DB04998 DB00812] DB04998|AGRO100 IKBKG DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 12860:[DB04998 DB00865] DB04998|AGRO100 IKBKG DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG 12861:[DB04998 DB13941] DB04998|AGRO100 IKBKG DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways 12862:[DB04998 DB00764] DB04998|AGRO100 IKBKG DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;IKBKG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PGR;IKBKG 12863:[DB04998 DB00694] DB04998|AGRO100 IKBKG DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0006974| response to DNA damage stimulus IKBKG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 12864:[DB04998 DB00189] DB04998|AGRO100 IKBKG DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 12865:[DB04998 DB09395] DB04998|AGRO100 IKBKG DB09395|Sodium acetate ACSS2 common genes common pathways 12866:[DB04998 DB01366] DB04998|AGRO100 IKBKG DB01366|Procaterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 12867:[DB04998 DB00385] DB04998|AGRO100 IKBKG DB00385|Valrubicin TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG 12868:[DB04998 DB14596] DB04998|AGRO100 IKBKG DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0006915| apoptotic process NR3C1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 12869:[DB04998 DB01656] DB04998|AGRO100 IKBKG DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways GO:0050852| T cell receptor signaling pathway PDE4B;IKBKG;PDE4D 12870:[DB04998 DB01440] DB04998|AGRO100 IKBKG DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 12871:[DB04998 DB08874] DB04998|AGRO100 IKBKG DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways 12872:[DB04998 DB13036] DB04998|AGRO100 IKBKG DB13036|Ramatroban PTGDR2 common genes common pathways GO:0006955| immune response PTGDR2;IKBKG 12873:[DB04998 DB01144] DB04998|AGRO100 IKBKG DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 12874:[DB04998 DB01623] DB04998|AGRO100 IKBKG DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG 12875:[DB04998 DB00033] DB04998|AGRO100 IKBKG DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways GO:0009615| response to virus IFNGR2;IFNGR1;IKBKG 12876:[DB04998 DB00857] DB04998|AGRO100 IKBKG DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1 12877:[DB04998 DB04829] DB04998|AGRO100 IKBKG DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG 12878:[DB04998 DB13997] DB04998|AGRO100 IKBKG DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways 12879:[DB04998 DB01083] DB04998|AGRO100 IKBKG DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways 12880:[DB04998 DB00691] DB04998|AGRO100 IKBKG DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0016032| viral reproduction IKBKG;ACE2 12881:[DB04998 DB05442] DB04998|AGRO100 IKBKG DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0000187| activation of MAPK activity IKBKG;IL1B GO:0006915| apoptotic process IL1B;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;IKBKG GO:0006954| inflammatory response IL1B;IKBKG GO:0006955| immune response IL1B;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;IKBKG 12882:[DB04998 DB09060] DB04998|AGRO100 IKBKG DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways 12883:[DB04998 DB00434] DB04998|AGRO100 IKBKG DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0006954| inflammatory response IKBKG;HRH1 GO:0009615| response to virus IKBKG;CHRM2 12884:[DB04998 DB00949] DB04998|AGRO100 IKBKG DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways 12885:[DB04998 DB08912] DB04998|AGRO100 IKBKG DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0050852| T cell receptor signaling pathway IKBKG;BRAF GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;RAF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;IKBKG GO:0006915| apoptotic process IKBKG;RAF1 12886:[DB04998 DB09258] DB04998|AGRO100 IKBKG DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways 12887:[DB04998 DB09046] DB04998|AGRO100 IKBKG DB09046|Metreleptin LEPR common genes common pathways 12888:[DB04998 DB05936] DB04998|AGRO100 IKBKG DB05936|CVT-6883 ADORA2B common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADORA2B GO:0007254| JNK cascade IKBKG;ADORA2B 12889:[DB04998 DB00347] DB04998|AGRO100 IKBKG DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways 12890:[DB04998 DB11755] DB04998|AGRO100 IKBKG DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0006955| immune response CNR2;IKBKG GO:0006954| inflammatory response CNR2;IKBKG 12891:[DB04998 DB00378] DB04998|AGRO100 IKBKG DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR GO:0006351| transcription, DNA-dependent IKBKG;PGR 12892:[DB04998 DB01005] DB04998|AGRO100 IKBKG DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways 12893:[DB04998 DB08918] DB04998|AGRO100 IKBKG DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways 12894:[DB04998 DB13168] DB04998|AGRO100 IKBKG DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;ALOX5 GO:0006355| regulation of transcription, DNA-dependent FADS1;IKBKG 12895:[DB04998 DB03066] DB04998|AGRO100 IKBKG DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 12896:[DB04998 DB00787] DB04998|AGRO100 IKBKG DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways 12897:[DB04998 DB09332] DB04998|AGRO100 IKBKG DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways 12898:[DB04998 DB01170] DB04998|AGRO100 IKBKG DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways 12899:[DB04998 DB00029] DB04998|AGRO100 IKBKG DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;SERPINE1 GO:0045087| innate immune response IKBKG;FGA 12900:[DB04998 DB03023] DB04998|AGRO100 IKBKG DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0038095| IKBKG;LYN GO:0050852| T cell receptor signaling pathway IKBKG;LCK GO:0006954| inflammatory response LYN;IKBKG GO:0016032| viral reproduction SRC;LYN;IKBKG;LCK GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;IKBKG;LYN GO:0009615| response to virus IKBKG;SRC GO:0045087| innate immune response LCK;IKBKG;LYN;SRC GO:0006974| response to DNA damage stimulus IKBKG;LYN 12901:[DB04998 DB11779] DB04998|AGRO100 IKBKG DB11779|Danoprevir CYP3A4 common genes common pathways 12902:[DB04998 DB00550] DB04998|AGRO100 IKBKG DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 12903:[DB04998 DB06419] DB04998|AGRO100 IKBKG DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways 12904:[DB04998 DB11960] DB04998|AGRO100 IKBKG DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways 12905:[DB04998 DB09052] DB04998|AGRO100 IKBKG DB09052|Blinatumomab CD19;CD3D common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CD3D;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;CD3D 12906:[DB04998 DB08834] DB04998|AGRO100 IKBKG DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways 12907:[DB04998 DB01129] DB04998|AGRO100 IKBKG DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 12908:[DB04998 DB06589] DB04998|AGRO100 IKBKG DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0006915| apoptotic process IKBKG;FGFR3 GO:0000187| activation of MAPK activity KIT;FGF1;IKBKG GO:0038095| IKBKG;ITK GO:0045087| innate immune response IKBKG;ITK GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;IKBKG GO:0016239| positive regulation of macroautophagy IKBKG;KDR GO:0016032| viral reproduction IKBKG;PDGFRA;KDR GO:0006954| inflammatory response IKBKG;KIT GO:0050852| T cell receptor signaling pathway ITK;IKBKG 12909:[DB04998 DB12489] DB04998|AGRO100 IKBKG DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways 12910:[DB04998 DB00698] DB04998|AGRO100 IKBKG DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways 12911:[DB04998 DB01261] DB04998|AGRO100 IKBKG DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways 12912:[DB04998 DB00145] DB04998|AGRO100 IKBKG DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways 12913:[DB04998 DB08892] DB04998|AGRO100 IKBKG DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways 12914:[DB04998 DB00830] DB04998|AGRO100 IKBKG DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways 12915:[DB04998 DB11805] DB04998|AGRO100 IKBKG DB11805|Saracatinib CYP3A4 common genes common pathways 12916:[DB04998 DB01708] DB04998|AGRO100 IKBKG DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0006351| transcription, DNA-dependent NR1I2;IKBKG;ESR2;ESR1;PPARA;NR1I3;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARA;GRIN1;NR1I3;IKBKG;ESR2;NR1I2 GO:1901215| GABRB3;PPARA;IKBKG;GABRB2 GO:0006355| regulation of transcription, DNA-dependent AR;NR1I3;PPARA;ESR1;IKBKG;ESR2;NR1I2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0016579| protein deubiquitination IKBKG;ESR1;AR 12917:[DB04998 DB01108] DB04998|AGRO100 IKBKG DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;IKBKG GO:0016579| protein deubiquitination IKBKG;ESR1 12918:[DB04998 DB04861] DB04998|AGRO100 IKBKG DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 12919:[DB04998 DB12243] DB04998|AGRO100 IKBKG DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways 12920:[DB04998 DB09198] DB04998|AGRO100 IKBKG DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARG GO:0045087| innate immune response PPARG;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG 12921:[DB04998 DB05449] DB04998|AGRO100 IKBKG DB05449|FM-VP4 ABCB1 common genes common pathways 12922:[DB04998 DB06733] DB04998|AGRO100 IKBKG DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 12923:[DB04998 DB02056] DB04998|AGRO100 IKBKG DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0006955| immune response IKBKG;PTGDR2 12924:[DB04998 DB01294] DB04998|AGRO100 IKBKG DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 12925:[DB04998 DB04821] DB04998|AGRO100 IKBKG DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG 12926:[DB04998 DB00193] DB04998|AGRO100 IKBKG DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0006955| immune response OPRD1;OPRK1;IKBKG GO:0000187| activation of MAPK activity IKBKG;CHRNA7 12927:[DB04998 DB01022] DB04998|AGRO100 IKBKG DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 12928:[DB04998 DB01075] DB04998|AGRO100 IKBKG DB01075|Diphenhydramine HRH1;CHRM2;CYP2D6;CYP2C9;CYP2C19;CYP2C18;PTGS1;SLC22A2;SLC22A5 common genes common pathways GO:0006954| inflammatory response PTGS1;HRH1;IKBKG GO:0009615| response to virus IKBKG;CHRM2 12929:[DB04998 DB04576] DB04998|AGRO100 IKBKG DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 12930:[DB04998 DB02337] DB04998|AGRO100 IKBKG DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 12931:[DB04998 DB04877] DB04998|AGRO100 IKBKG DB04877|Voacamine ABCB1 common genes common pathways 12932:[DB04998 DB00611] DB04998|AGRO100 IKBKG DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0006955| immune response OPRK1;IKBKG;OPRD1 12933:[DB04998 DB02105] DB04998|AGRO100 IKBKG DB02105|3,5-Dinitrocatechol COMT common genes common pathways 12934:[DB04998 DB09072] DB04998|AGRO100 IKBKG DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways 12935:[DB04998 DB03203] DB04998|AGRO100 IKBKG DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways GO:0016032| viral reproduction PVR;IKBKG 12936:[DB04998 DB13988] DB04998|AGRO100 IKBKG DB13988|SB-269970 HTR7 common genes common pathways 12937:[DB04998 DB00726] DB04998|AGRO100 IKBKG DB00726|Trimipramine SLC6A4;SLC6A2;SLC6A3;HTR2A;HTR1A;ADRA1A;ADRA1B;DRD2;ADRA2B;HRH1;HTR2C;HTR3A;HTR1D;ADRA2A;DRD1;DRD5;ADRB1;ADRB2;ADRB3;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0009615| response to virus IKBKG;CHRM2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG;DRD2 GO:0006954| inflammatory response IKBKG;HRH1 GO:0016032| viral reproduction HTR2A;IKBKG 12938:[DB04998 DB00745] DB04998|AGRO100 IKBKG DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways 12939:[DB04998 DB06770] DB04998|AGRO100 IKBKG DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 12940:[DB04998 DB01234] DB04998|AGRO100 IKBKG DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0006915| apoptotic process NR3C1;IKBKG GO:0006954| inflammatory response IKBKG;ANXA1 GO:0006355| regulation of transcription, DNA-dependent NR0B1;IKBKG;NR1I2;NR3C1 GO:0045087| innate immune response ANXA1;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;NR0B1;IKBKG;NR1I2 12941:[DB04998 DB00779] DB04998|AGRO100 IKBKG DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways 12942:[DB04998 DB01016] DB04998|AGRO100 IKBKG DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;CFTR 12943:[DB04998 DB05928] DB04998|AGRO100 IKBKG DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 12944:[DB04998 DB13952] DB04998|AGRO100 IKBKG DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR1I2;ESRRG;ESR2;IKBKG;ESR1 GO:0016032| viral reproduction IKBKG;BECN1 GO:0006954| inflammatory response GPER1;IKBKG GO:0006351| transcription, DNA-dependent ESR1;NR1I2;NCOA2;ESR2;IKBKG;ESRRG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GPER1;NCOA2;NR1I2;ESRRG;ESR2;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045087| innate immune response GPER1;IKBKG GO:0006915| apoptotic process BECN1;IKBKG;GPER1 GO:0016579| protein deubiquitination ESR1;IKBKG;BECN1 12945:[DB04998 DB06704] DB04998|AGRO100 IKBKG DB06704|Iobenguane SLC6A2 common genes common pathways 12946:[DB04998 DB00142] DB04998|AGRO100 IKBKG DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0000187| activation of MAPK activity GRM4;GRM1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 12947:[DB04998 DB00872] DB04998|AGRO100 IKBKG DB00872|Conivaptan AVPR1A;AVPR2;CYP3A4 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;AVPR2 12948:[DB04998 DB00439] DB04998|AGRO100 IKBKG DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways 12949:[DB04998 DB00593] DB04998|AGRO100 IKBKG DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways 12950:[DB04998 DB00508] DB04998|AGRO100 IKBKG DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0009615| response to virus CHRM2;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B 12951:[DB04998 DB06594] DB04998|AGRO100 IKBKG DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways 12952:[DB04998 DB00486] DB04998|AGRO100 IKBKG DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0006955| immune response IKBKG;CNR2 GO:0006954| inflammatory response IKBKG;CNR2 12953:[DB04998 DB05120] DB04998|AGRO100 IKBKG DB05120|AT1391 INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent INSR;IKBKG GO:0000187| activation of MAPK activity INSR;IKBKG 12954:[DB04998 DB09207] DB04998|AGRO100 IKBKG DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 12955:[DB04998 DB00198] DB04998|AGRO100 IKBKG DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways 12956:[DB04998 DB00188] DB04998|AGRO100 IKBKG DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0016032| viral reproduction PSMB1;PSMB5;IKBKG GO:0050852| T cell receptor signaling pathway PSMB5;PSMB1;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;PSMB5;PSMB1 GO:0002223| stimulatory C-type lectin receptor signaling pathway PSMB5;PSMB1;IKBKG GO:0016579| protein deubiquitination PSMB5;PSMB1;IKBKG GO:0038095| PSMB1;PSMB5;IKBKG 12957:[DB04998 DB08871] DB04998|AGRO100 IKBKG DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0006915| apoptotic process BCL2;IKBKG GO:0006974| response to DNA damage stimulus BCL2;IKBKG 12958:[DB04998 DB00304] DB04998|AGRO100 IKBKG DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0006351| transcription, DNA-dependent IKBKG;PGR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG;PGR GO:0006355| regulation of transcription, DNA-dependent ESR1;PGR;IKBKG 12959:[DB04998 DB09223] DB04998|AGRO100 IKBKG DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG 12960:[DB04998 DB09285] DB04998|AGRO100 IKBKG DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0006954| inflammatory response TBXA2R;ALOX5;PTGS2;LTB4R;IKBKG GO:0006955| immune response LTB4R;IKBKG 12961:[DB04998 DB01106] DB04998|AGRO100 IKBKG DB01106|Levocabastine HRH1;NTSR2 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 12962:[DB04998 DB01210] DB04998|AGRO100 IKBKG DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination ADRB2;IKBKG 12963:[DB04998 DB06217] DB04998|AGRO100 IKBKG DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways 12964:[DB04998 DB02266] DB04998|AGRO100 IKBKG DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG;PPARA;AR GO:0045087| innate immune response IKBKG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;AR;PPARG;IKBKG GO:0006351| transcription, DNA-dependent PPARG;IKBKG;PPARA;AR GO:0016579| protein deubiquitination AR;IKBKG 12965:[DB04998 DB02377] DB04998|AGRO100 IKBKG DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0006955| immune response PNP;IKBKG 12966:[DB04998 DB01209] DB04998|AGRO100 IKBKG DB01209|Dezocine OPRM1;OPRK1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1 12967:[DB04998 DB01174] DB04998|AGRO100 IKBKG DB01174|Phenobarbital GABRA1;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP2C19;CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2;CYP2A6;CYP2E1;CYP3A5;CYP4A11;CYP1A1;CYP1B1;CYP2C18;CYP3A7;CYP4B1;UGT1A1;UGT2B7;ABCB1;ABCC3;ABCB11;ABCC1;SLCO2A1;ABCC2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG;NR1I2 GO:0009615| response to virus CYP1A1;IKBKG GO:0000187| activation of MAPK activity CHRNA7;IKBKG 12968:[DB04998 DB08992] DB04998|AGRO100 IKBKG DB08992|Eperisone CYP3A4 common genes common pathways 12969:[DB04998 DB11251] DB04998|AGRO100 IKBKG DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0016032| viral reproduction SCARB1;IKBKG;LDLR GO:0006355| regulation of transcription, DNA-dependent SEC14L2;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;SEC14L2 12970:[DB04998 DB00973] DB04998|AGRO100 IKBKG DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0016032| viral reproduction ANPEP;IKBKG 12971:[DB04998 DB01577] DB04998|AGRO100 IKBKG DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B 12972:[DB04998 DB09330] DB04998|AGRO100 IKBKG DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IKBKG 12973:[DB04998 DB05740] DB04998|AGRO100 IKBKG DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 12974:[DB04998 DB00451] DB04998|AGRO100 IKBKG DB00451|Levothyroxine THRA;THRB;CYP2C8;UGT1A1;TTR;SERPINA7;ALB;SLCO1C1;SLC16A2;ABCB1;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4A1;SLCO4C1;SLC7A5;SLCO2B1 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;THRB;THRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;THRB;THRA GO:0006355| regulation of transcription, DNA-dependent THRA;THRB;IKBKG 12975:[DB04998 DB06362] DB04998|AGRO100 IKBKG DB06362|Becatecarin TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 12976:[DB04998 DB03052] DB04998|AGRO100 IKBKG DB03052|Dazoxiben TBXAS1 common genes common pathways 12977:[DB04998 DB00473] DB04998|AGRO100 IKBKG DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 12978:[DB04998 DB00441] DB04998|AGRO100 IKBKG DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways 12979:[DB04998 DB01046] DB04998|AGRO100 IKBKG DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways 12980:[DB04998 DB03147] DB04998|AGRO100 IKBKG DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0006915| apoptotic process IKBKG;AIFM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NOS1 GO:0006351| transcription, DNA-dependent IKBKG;ACAD8 GO:0016032| viral reproduction IKBKG;TPR GO:0006355| regulation of transcription, DNA-dependent IKBKG;ACAD8 12981:[DB04998 DB00235] DB04998|AGRO100 IKBKG DB00235|Milrinone PDE3A common genes common pathways 12982:[DB04998 DB00540] DB04998|AGRO100 IKBKG DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0006954| inflammatory response IKBKG;ORM1;PTGS1;HRH1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;ADRB2 GO:0009615| response to virus IKBKG;CHRM2 GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0006915| apoptotic process ADRA1A;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 12983:[DB04998 DB05015] DB04998|AGRO100 IKBKG DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0006954| inflammatory response HDAC5;HDAC9;IKBKG;HDAC4 GO:0016032| viral reproduction IKBKG;HDAC1 GO:0006355| regulation of transcription, DNA-dependent HDAC4;HDAC1;IKBKG;HDAC11;HDAC7;HDAC6;HDAC10;HDAC5;HDAC8;HDAC2;HDAC9;HDAC3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;HDAC4;HDAC1;HDAC5;HDAC2;HDAC3 GO:0006351| transcription, DNA-dependent HDAC3;HDAC9;HDAC5;HDAC8;HDAC2;HDAC10;HDAC6;HDAC11;HDAC7;IKBKG;HDAC1;HDAC4 12984:[DB04998 DB01396] DB04998|AGRO100 IKBKG DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways 12985:[DB04998 DB01390] DB04998|AGRO100 IKBKG DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways 12986:[DB04998 DB06717] DB04998|AGRO100 IKBKG DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways 12987:[DB04998 DB03619] DB04998|AGRO100 IKBKG DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0006954| inflammatory response NR1H4;IKBKG GO:0016032| viral reproduction IKBKG;SLC10A1 GO:0006355| regulation of transcription, DNA-dependent NR1H4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1H4 GO:0045087| innate immune response IKBKG;NR1H4 GO:0006351| transcription, DNA-dependent IKBKG;NR1H4 12988:[DB04998 DB00404] DB04998|AGRO100 IKBKG DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG 12989:[DB04998 DB01407] DB04998|AGRO100 IKBKG DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IKBKG GO:0006954| inflammatory response TNF;IKBKG GO:0006955| immune response TNF;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG;TNF GO:0009615| response to virus IKBKG;CYP1A1;TNF GO:0000187| activation of MAPK activity IKBKG;TNF GO:0007254| JNK cascade IKBKG;TNF GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;TNF 12990:[DB04998 DB01439] DB04998|AGRO100 IKBKG DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response OPRK1;IKBKG;OPRD1 12991:[DB04998 DB00072] DB04998|AGRO100 IKBKG DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0006351| transcription, DNA-dependent ERBB2;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response C1QC;C1S;C1QA;C1QB;C1R;FCGR1A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;EGFR GO:0006355| regulation of transcription, DNA-dependent ERBB2;IKBKG GO:0016032| viral reproduction IKBKG;FCGR2B GO:0006955| immune response FCGR3A;FCGR2C;C1QC;IKBKG;FCGR1A;C1R;FCGR2B;FCGR3B GO:0006954| inflammatory response FCGR2B;IKBKG 12992:[DB04998 DB00959] DB04998|AGRO100 IKBKG DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG 12993:[DB04998 DB01411] DB04998|AGRO100 IKBKG DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0038095| IKBKG;NFKB1 GO:0007254| JNK cascade TNF;IKBKG GO:0000187| activation of MAPK activity IKBKG;TNF GO:0006915| apoptotic process NFKB1;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB1;TNF;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NFKB1 GO:0050852| T cell receptor signaling pathway NFKB1;IKBKG GO:0006954| inflammatory response TNF;IKBKG;NFKB1;IL5 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;TNF;IKBKG GO:0006955| immune response TNF;IKBKG;IL5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNF GO:0002223| stimulatory C-type lectin receptor signaling pathway MUC2;IKBKG;NFKB1 GO:0051403| stress-activated MAPK cascade IKBKG;NFKB1 GO:0006351| transcription, DNA-dependent NFKB1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;IKBKG;TNF GO:0009615| response to virus TNF;IKBKG GO:0045087| innate immune response RNASE3;IKBKG;NFKB1 12994:[DB04998 DB00041] DB04998|AGRO100 IKBKG DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0006955| immune response IKBKG;IL2RG;IL2RA GO:0016032| viral reproduction IL2RB;IKBKG;IL2RG GO:0006954| inflammatory response IKBKG;PTGS2;IL2RA GO:0006915| apoptotic process IL2RA;IKBKG 12995:[DB04998 DB13146] DB04998|AGRO100 IKBKG DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0016032| viral reproduction SLC1A5;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 12996:[DB04998 DB09555] DB04998|AGRO100 IKBKG DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0006954| inflammatory response HRH1;IKBKG 12997:[DB04998 DB01429] DB04998|AGRO100 IKBKG DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0038095| CALM1;IKBKG GO:0006954| inflammatory response IKBKG;ORM1 12998:[DB04998 DB09338] DB04998|AGRO100 IKBKG DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways 12999:[DB04998 DB00379] DB04998|AGRO100 IKBKG DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AHR GO:0006351| transcription, DNA-dependent IKBKG;AHR GO:0006355| regulation of transcription, DNA-dependent AHR;IKBKG GO:0006915| apoptotic process AHR;IKBKG 13000:[DB04998 DB09418] DB04998|AGRO100 IKBKG DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways 13001:[DB04998 DB00526] DB04998|AGRO100 IKBKG DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG GO:0000187| activation of MAPK activity IKBKG;SOD1 13002:[DB04998 DB01127] DB04998|AGRO100 IKBKG DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG 13003:[DB04998 DB12952] DB04998|AGRO100 IKBKG DB12952|Methylprednisone CYP3A4 common genes common pathways 13004:[DB04998 DB00380] DB04998|AGRO100 IKBKG DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 13005:[DB04998 DB00195] DB04998|AGRO100 IKBKG DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 13006:[DB04998 DB04789] DB04998|AGRO100 IKBKG DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways 13007:[DB04998 DB09288] DB04998|AGRO100 IKBKG DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes common pathways GO:0006954| inflammatory response TRPV1;IKBKG;PTGS2;PTGS1 GO:1901215| SULT1A3;IKBKG 13008:[DB04998 DB01363] DB04998|AGRO100 IKBKG DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG 13009:[DB04998 DB00499] DB04998|AGRO100 IKBKG DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent AR;IKBKG;AHR;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AHR;NR1I2;AR GO:0009615| response to virus IKBKG;CYP1A1 GO:0006351| transcription, DNA-dependent AR;IKBKG;AHR;NR1I2 GO:0016579| protein deubiquitination AR;IKBKG GO:0006915| apoptotic process IKBKG;AHR 13010:[DB04998 DB14540] DB04998|AGRO100 IKBKG DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006955| immune response IKBKG;CYP11B1 GO:0006954| inflammatory response ANXA1;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0045087| innate immune response IKBKG;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 13011:[DB04998 DB01369] DB04998|AGRO100 IKBKG DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways 13012:[DB04998 DB00474] DB04998|AGRO100 IKBKG DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways 13013:[DB04998 DB13953] DB04998|AGRO100 IKBKG DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I2;NCOA2;IKBKG;ESR2;ESRRG GO:0016032| viral reproduction BECN1;IKBKG GO:0006954| inflammatory response IKBKG;GPER1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;NR1I2;ESRRG;IKBKG;ESR2 GO:0045087| innate immune response IKBKG;GPER1 GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GPER1;NCOA2;NR1I2;ESRRG;IKBKG;ESR2 GO:0006915| apoptotic process BECN1;IKBKG;GPER1 GO:0016579| protein deubiquitination ESR1;BECN1;IKBKG 13014:[DB04998 DB09291] DB04998|AGRO100 IKBKG DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways 13015:[DB04998 DB01351] DB04998|AGRO100 IKBKG DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13016:[DB04998 DB01380] DB04998|AGRO100 IKBKG DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 13017:[DB04998 DB00435] DB04998|AGRO100 IKBKG DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0006954| inflammatory response IDO1;IKBKG 13018:[DB04998 DB13872] DB04998|AGRO100 IKBKG DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways 13019:[DB04998 DB14503] DB04998|AGRO100 IKBKG DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;IKBKG GO:0016032| viral reproduction SLC20A2;IKBKG 13020:[DB04998 DB06190] DB04998|AGRO100 IKBKG DB06190|Solabegron ADRB3 common genes common pathways 13021:[DB04998 DB06787] DB04998|AGRO100 IKBKG DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 13022:[DB04998 DB06652] DB04998|AGRO100 IKBKG DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0006955| immune response CCR5;IKBKG GO:0016032| viral reproduction CCR5;IKBKG GO:0006954| inflammatory response IKBKG;CCR5 13023:[DB04998 DB06412] DB04998|AGRO100 IKBKG DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent AR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;IKBKG GO:0006351| transcription, DNA-dependent AR;IKBKG GO:0016579| protein deubiquitination IKBKG;AR 13024:[DB04998 DB01228] DB04998|AGRO100 IKBKG DB01228|Encainide SCN5A;CYP2D6 common genes common pathways 13025:[DB04998 DB00604] DB04998|AGRO100 IKBKG DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG 13026:[DB04998 DB08901] DB04998|AGRO100 IKBKG DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0038095| LYN;IKBKG GO:0000187| activation of MAPK activity IKBKG;KIT GO:0006915| apoptotic process FGFR3;ABL1;IKBKG;FGFR2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;IKBKG GO:0006351| transcription, DNA-dependent FGFR1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;IKBKG GO:0009615| response to virus IKBKG;SRC GO:0045087| innate immune response SRC;IKBKG;ABL1;LCK;LYN GO:0006974| response to DNA damage stimulus IKBKG;ABL1;LYN GO:0006355| regulation of transcription, DNA-dependent FGFR1;IKBKG;ABL1 GO:0050852| T cell receptor signaling pathway IKBKG;LCK GO:0006954| inflammatory response LYN;IKBKG;KIT GO:0016032| viral reproduction SRC;LYN;IKBKG;LCK;KDR;PDGFRA GO:0016239| positive regulation of macroautophagy KDR;IKBKG 13027:[DB04998 DB11581] DB04998|AGRO100 IKBKG DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0006915| apoptotic process IKBKG;BCL2 GO:0006974| response to DNA damage stimulus IKBKG;BCL2 13028:[DB04998 DB01138] DB04998|AGRO100 IKBKG DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG 13029:[DB04998 DB06713] DB04998|AGRO100 IKBKG DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent AR;IKBKG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR;AR GO:0006351| transcription, DNA-dependent AR;IKBKG;PGR GO:0016579| protein deubiquitination AR;IKBKG 13030:[DB04998 DB00637] DB04998|AGRO100 IKBKG DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 13031:[DB04998 DB01252] DB04998|AGRO100 IKBKG DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARG GO:0045087| innate immune response PPARG;IKBKG GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG 13032:[DB04998 DB00814] DB04998|AGRO100 IKBKG DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 13033:[DB04998 DB06262] DB04998|AGRO100 IKBKG DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13034:[DB04998 DB01254] DB04998|AGRO100 IKBKG DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0006351| transcription, DNA-dependent BTK;NR4A3;STAT5B;IKBKG;HSPA8;MAPK14 GO:0002223| stimulatory C-type lectin receptor signaling pathway SRC;LYN;FYN;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ABL1;FYN GO:0009615| response to virus FGR;SRC;CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter STAT5B;NR4A3;MAPK14;YES1;IKBKG GO:0006974| response to DNA damage stimulus LYN;MAPK14;IKBKG;ABL1 GO:0045087| innate immune response ABL2;FGR;BTK;SRC;LYN;FYN;FRK;CSK;IKBKG;YES1;ABL1;LCK GO:0006355| regulation of transcription, DNA-dependent HSPA8;MAPK14;IKBKG;ABL1;NR4A3;BTK;STAT5B GO:0050852| T cell receptor signaling pathway CSK;IKBKG;LCK;FYN GO:0016032| viral reproduction SRC;HSPA8;LYN;EPHA2;FYN;LCK;IKBKG GO:0006954| inflammatory response IKBKG;LYN;KIT GO:0051092| positive regulation of NF-kappaB transcription factor activity BTK;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade BTK;IKBKG GO:0038095| LYN;IKBKG;BTK GO:0006915| apoptotic process EPHA2;MAPK14;ABL1;IKBKG;BTK GO:0000187| activation of MAPK activity MAPK14;IKBKG;KIT 13035:[DB04998 DB01059] DB04998|AGRO100 IKBKG DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0006974| response to DNA damage stimulus IKBKG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0009615| response to virus CYP1A1;IKBKG 13036:[DB04998 DB05303] DB04998|AGRO100 IKBKG DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0000187| activation of MAPK activity TNF;IKBKG GO:0007254| JNK cascade TNF;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TNF GO:0009615| response to virus IKBKG;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TNF GO:0006954| inflammatory response IKBKG;TNF GO:0006955| immune response TNF;IL1R1;IKBKG 13037:[DB04998 DB00002] DB04998|AGRO100 IKBKG DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response C1QA;C1S;C1QC;IKBKG;FCGR1A;C1QB;C1R GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;EGFR GO:0006955| immune response FCGR1A;IKBKG;C1R;FCGR2B;FCGR3B;FCGR3A;FCGR2C;C1QC GO:0016032| viral reproduction FCGR2B;IKBKG GO:0006954| inflammatory response IKBKG;FCGR2B 13038:[DB04998 DB02701] DB04998|AGRO100 IKBKG DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0006915| apoptotic process IKBKG;PARP1 GO:0006351| transcription, DNA-dependent IKBKG;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;IKBKG GO:0006974| response to DNA damage stimulus PARP1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;PARP1 13039:[DB04998 DB00338] DB04998|AGRO100 IKBKG DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0006915| apoptotic process AHR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;AHR GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;IKBKG GO:0006355| regulation of transcription, DNA-dependent AHR;IKBKG 13040:[DB04998 DB09146] DB04998|AGRO100 IKBKG DB09146|Iron saccharate HBA1;TF common genes common pathways 13041:[DB04998 DB09449] DB04998|AGRO100 IKBKG DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction IKBKG;SLC20A2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;IKBKG 13042:[DB04998 DB00533] DB04998|AGRO100 IKBKG DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13043:[DB04998 DB00083] DB04998|AGRO100 IKBKG DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways GO:0006915| apoptotic process RHOB;IKBKG 13044:[DB04998 DB13269] DB04998|AGRO100 IKBKG DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0006954| inflammatory response SCN9A;IKBKG 13045:[DB04998 DB06772] DB04998|AGRO100 IKBKG DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 13046:[DB04998 DB13950] DB04998|AGRO100 IKBKG DB13950|WIN 55212-2 CYP3A4 common genes common pathways 13047:[DB04998 DB01395] DB04998|AGRO100 IKBKG DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;IKBKG GO:0006351| transcription, DNA-dependent PGR;IKBKG;NR3C2;AR GO:0006954| inflammatory response IKBKG;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent PGR;IKBKG;NR3C2;AR GO:0016579| protein deubiquitination IKBKG;AR 13048:[DB04998 DB01126] DB04998|AGRO100 IKBKG DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways 13049:[DB04998 DB06370] DB04998|AGRO100 IKBKG DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways 13050:[DB04998 DB13866] DB04998|AGRO100 IKBKG DB13866|Etynodiol CYP3A4 common genes common pathways 13051:[DB04998 DB11348] DB04998|AGRO100 IKBKG DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0038095| CALM1;IKBKG GO:0007254| JNK cascade IKBKG;CASR GO:0006915| apoptotic process CASR;CIB1;PDCD6;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;CIB1 GO:0016032| viral reproduction SLC20A2;IKBKG GO:0006355| regulation of transcription, DNA-dependent CALR;IKBKG GO:0050852| T cell receptor signaling pathway CACNB3;IKBKG GO:0009615| response to virus IKBKG;TPT1 GO:0045087| innate immune response IKBKG;S100B GO:0006974| response to DNA damage stimulus CIB1;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent CALR;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;S100A13;SLC20A1;IKBKG 13052:[DB04998 DB09389] DB04998|AGRO100 IKBKG DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;PGR;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0016579| protein deubiquitination IKBKG;AR 13053:[DB04998 DB12191] DB04998|AGRO100 IKBKG DB12191|Obatoclax BCL2 common genes common pathways GO:0006974| response to DNA damage stimulus BCL2;IKBKG GO:0006915| apoptotic process IKBKG;BCL2 13054:[DB04998 DB08807] DB04998|AGRO100 IKBKG DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination ADRB2;IKBKG 13055:[DB04998 DB11130] DB04998|AGRO100 IKBKG DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;B2M GO:0045087| innate immune response B2M;IKBKG GO:0006955| immune response OPRD1;OPRK1;IKBKG;B2M 13056:[DB04998 DB06734] DB04998|AGRO100 IKBKG DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 13057:[DB04998 DB00589] DB04998|AGRO100 IKBKG DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0000187| activation of MAPK activity DRD4;ADRA2B;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;IKBKG;DRD2 13058:[DB04998 DB09502] DB04998|AGRO100 IKBKG DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways 13059:[DB04998 DB05505] DB04998|AGRO100 IKBKG DB05505|NM-702 TBXAS1 common genes common pathways 13060:[DB04998 DB01200] DB04998|AGRO100 IKBKG DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;DRD4;ADRA2B GO:0006915| apoptotic process ADRA1A;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 13061:[DB04998 DB01240] DB04998|AGRO100 IKBKG DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways 13062:[DB04998 DB11607] DB04998|AGRO100 IKBKG DB11607|Efmoroctocog alfa VWF common genes common pathways 13063:[DB04998 DB05039] DB04998|AGRO100 IKBKG DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13064:[DB04998 DB04825] DB04998|AGRO100 IKBKG DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0038095| CALM1;IKBKG 13065:[DB04998 DB05476] DB04998|AGRO100 IKBKG DB05476|WX-UK1 PLAUR common genes common pathways 13066:[DB04998 DB09029] DB04998|AGRO100 IKBKG DB09029|Secukinumab IL17A common genes common pathways GO:0006915| apoptotic process IL17A;IKBKG GO:0006954| inflammatory response IL17A;IKBKG GO:0006955| immune response IKBKG;IL17A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;IL17A 13067:[DB04998 DB00836] DB04998|AGRO100 IKBKG DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0038095| CALM1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR1I3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I3;POMC GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I3 GO:0006955| immune response IKBKG;OPRK1;OPRD1 13068:[DB04998 DB00210] DB04998|AGRO100 IKBKG DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RARG;RARA;IKBKG;RXRG;RARB;RXRB;RXRA GO:0016032| viral reproduction IKBKG;RXRA GO:0006954| inflammatory response IKBKG;PTGS2 GO:0006351| transcription, DNA-dependent RARA;RARG;RARB;IKBKG;RXRG;RXRB;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;RXRA;RARB;IKBKG;RXRG;RARA;RARG 13069:[DB04998 DB12332] DB04998|AGRO100 IKBKG DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0006915| apoptotic process IKBKG;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PARP1 GO:0006974| response to DNA damage stimulus IKBKG;PARP1 GO:0006351| transcription, DNA-dependent PARP1;IKBKG 13070:[DB04998 DB05431] DB04998|AGRO100 IKBKG DB05431|MLN-977 ALOX5 common genes common pathways GO:0006954| inflammatory response IKBKG;ALOX5 13071:[DB04998 DB02998] DB04998|AGRO100 IKBKG DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0016579| protein deubiquitination AR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR;NCOA2;AR GO:0006351| transcription, DNA-dependent AR;NR3C2;IKBKG;PGR;NCOA2 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent NCOA2;IKBKG;NR3C2;PGR;AR 13072:[DB04998 DB14635] DB04998|AGRO100 IKBKG DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG;VDR GO:0006351| transcription, DNA-dependent VDR;PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;IKBKG;PPARG GO:0045087| innate immune response PPARG;IKBKG 13073:[DB04998 DB00877] DB04998|AGRO100 IKBKG DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;IKBKG GO:0043276| anoikis MTOR;IKBKG GO:0000187| activation of MAPK activity IKBKG;FGF2 13074:[DB04998 DB11712] DB04998|AGRO100 IKBKG DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0016579| protein deubiquitination IKBKG;CFTR 13075:[DB04998 DB12334] DB04998|AGRO100 IKBKG DB12334|Milataxel TUBB1;TUBB common genes common pathways 13076:[DB04998 DB07462] DB04998|AGRO100 IKBKG DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways 13077:[DB04998 DB09303] DB04998|AGRO100 IKBKG DB09303|Evolocumab PCSK9 common genes common pathways GO:0006915| apoptotic process IKBKG;PCSK9 13078:[DB04998 DB06212] DB04998|AGRO100 IKBKG DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;IKBKG 13079:[DB04998 DB05668] DB04998|AGRO100 IKBKG DB05668|Palifosfamide DNMT1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;DNMT1 GO:0006351| transcription, DNA-dependent IKBKG;DNMT1 13080:[DB04998 DB03403] DB04998|AGRO100 IKBKG DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 13081:[DB04998 DB00685] DB04998|AGRO100 IKBKG DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 13082:[DB04998 DB06237] DB04998|AGRO100 IKBKG DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways 13083:[DB04998 DB04074] DB04998|AGRO100 IKBKG DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 13084:[DB04998 DB01102] DB04998|AGRO100 IKBKG DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination IKBKG;ADRB2 13085:[DB04998 DB04843] DB04998|AGRO100 IKBKG DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways 13086:[DB04998 DB11703] DB04998|AGRO100 IKBKG DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0038095| BTK;IKBKG GO:0006915| apoptotic process BTK;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;BTK GO:0051092| positive regulation of NF-kappaB transcription factor activity BTK;IKBKG GO:0006355| regulation of transcription, DNA-dependent BTK;IKBKG GO:0045087| innate immune response IKBKG;BTK GO:0006351| transcription, DNA-dependent BTK;IKBKG 13087:[DB04998 DB00655] DB04998|AGRO100 IKBKG DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;ESR2;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006351| transcription, DNA-dependent AR;ESR1;ESR2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;ESR2;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0016579| protein deubiquitination AR;ESR1;IKBKG 13088:[DB04998 DB00696] DB04998|AGRO100 IKBKG DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;IKBKG 13089:[DB04998 DB05087] DB04998|AGRO100 IKBKG DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways 13090:[DB04998 DB04840] DB04998|AGRO100 IKBKG DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13091:[DB04998 DB00886] DB04998|AGRO100 IKBKG DB00886|Omapatrilat ACE;MME common genes common pathways 13092:[DB04998 DB05351] DB04998|AGRO100 IKBKG DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways 13093:[DB04998 DB14642] DB04998|AGRO100 IKBKG DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;IKBKG 13094:[DB04998 DB01219] DB04998|AGRO100 IKBKG DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways 13095:[DB04998 DB00845] DB04998|AGRO100 IKBKG DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways 13096:[DB04998 DB09065] DB04998|AGRO100 IKBKG DB09065|Cobicistat CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 13097:[DB04998 DB09166] DB04998|AGRO100 IKBKG DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0006955| immune response PTAFR;IKBKG GO:0006954| inflammatory response PTAFR;IKBKG 13098:[DB04998 DB04889] DB04998|AGRO100 IKBKG DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG 13099:[DB04998 DB00782] DB04998|AGRO100 IKBKG DB00782|Propantheline CHRM1 common genes common pathways 13100:[DB04998 DB14508] DB04998|AGRO100 IKBKG DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:1901215| GSK3B;IKBKG 13101:[DB04998 DB00502] DB04998|AGRO100 IKBKG DB00502|Haloperidol DRD2;DRD1;GRIN2B;HTR2A;DRD3;MCHR1;SLC18A2;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP3A4;CBR1;UGT1A9;CYP1A1;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0009615| response to virus CYP1A1;IKBKG 13102:[DB04998 DB01008] DB04998|AGRO100 IKBKG DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways 13103:[DB04998 DB00503] DB04998|AGRO100 IKBKG DB00503|Ritonavir pol;NR1I2;CYP2D6;CYP2C9;CYP2C19;CYP2B6;CYP2C8;CYP1A2;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;UGT1A1;ALB;ABCB1;ABCC1;SLCO1A2;ABCC2;ABCG2;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG 13104:[DB04998 DB06211] DB04998|AGRO100 IKBKG DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0006915| apoptotic process IKBKG;DPEP1 13105:[DB04998 DB00517] DB04998|AGRO100 IKBKG DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 13106:[DB04998 DB08838] DB04998|AGRO100 IKBKG DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 GO:0006915| apoptotic process NISCH;IKBKG 13107:[DB04998 DB00131] DB04998|AGRO100 IKBKG DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0000187| activation of MAPK activity IKBKG;PRKAA1 GO:0006915| apoptotic process PIM1;HINT1;IKBKG GO:0016032| viral reproduction IKBKG;CREB1 GO:0006355| regulation of transcription, DNA-dependent PRKAA1;IKBKG;CREB1;HINT1 GO:0050852| T cell receptor signaling pathway PDE4D;IKBKG;PDE4B GO:1901215| CREB1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;CREB1 GO:0006351| transcription, DNA-dependent PRKAA1;IKBKG;CREB1;HINT1 13108:[DB04998 DB00594] DB04998|AGRO100 IKBKG DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;IKBKG 13109:[DB04998 DB06288] DB04998|AGRO100 IKBKG DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG 13110:[DB04998 DB00569] DB04998|AGRO100 IKBKG DB00569|Fondaparinux SERPINC1;F10 common genes common pathways 13111:[DB04998 DB11358] DB04998|AGRO100 IKBKG DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;FADS1 13112:[DB04998 DB09282] DB04998|AGRO100 IKBKG DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 13113:[DB04998 DB00630] DB04998|AGRO100 IKBKG DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0016032| viral reproduction IKBKG;FDPS 13114:[DB04998 DB00237] DB04998|AGRO100 IKBKG DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG GO:0000187| activation of MAPK activity IKBKG;CHRNA7 13115:[DB04998 DB11094] DB04998|AGRO100 IKBKG DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;VDR GO:0006351| transcription, DNA-dependent IKBKG;VDR GO:0006355| regulation of transcription, DNA-dependent VDR;IKBKG 13116:[DB04998 DB01080] DB04998|AGRO100 IKBKG DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways 13117:[DB04998 DB09053] DB04998|AGRO100 IKBKG DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;BTK GO:0038095| IKBKG;BTK GO:0006915| apoptotic process IKBKG;BTK GO:0006351| transcription, DNA-dependent IKBKG;BTK GO:0045087| innate immune response BTK;IKBKG GO:0006355| regulation of transcription, DNA-dependent BTK;IKBKG GO:0006954| inflammatory response ORM1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;BTK 13118:[DB04998 DB00276] DB04998|AGRO100 IKBKG DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 13119:[DB04998 DB00458] DB04998|AGRO100 IKBKG DB00458|Imipramine SLC6A2;HTR2A;SLC6A4;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCND2;KCND3;HTR2C;ADRA1B;HTR7;DRD1;DRD5;DRD2;KCNH2;SLC6A3;HTR1A;HTR6;KCNH1;ORM2;CYP2C19;CYP2D6;CYP1A2;CYP3A4;CYP3A7;CYP2B6;CYP2C18;CYP2E1;ORM1;ALB;ABCB1;SLC22A2;SLC22A3;SLC22A4 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0006954| inflammatory response HRH1;ORM1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 GO:0009615| response to virus CHRM2;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 13120:[DB04998 DB00346] DB04998|AGRO100 IKBKG DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 13121:[DB04998 DB09265] DB04998|AGRO100 IKBKG DB09265|Lixisenatide GLP1R common genes common pathways 13122:[DB04998 DB11586] DB04998|AGRO100 IKBKG DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways 13123:[DB04998 DB00675] DB04998|AGRO100 IKBKG DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;PRKCB;PRKCE GO:0002223| stimulatory C-type lectin receptor signaling pathway PRKCD;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;ESR2;IKBKG;ESRRG;ESR1;AR;PRKCB GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;IKBKG;ESR2;ESRRG;NR1I2 GO:0009615| response to virus CYP1A1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;PRKCB;NR1I2;ESR2;IKBKG;PRKCQ;ESRRG GO:0050852| T cell receptor signaling pathway PRKCQ;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCB;PRKCI;PRKCZ;AR;PRKCQ;IKBKG GO:0006954| inflammatory response PRKCZ;PRKCQ;IKBKG GO:0038095| IKBKG;PRKCQ GO:0006915| apoptotic process PRKCA;IKBKG;PRKCD;PRKCB;PRKCE GO:0016579| protein deubiquitination IKBKG;ESR1;AR 13124:[DB04998 DB14065] DB04998|AGRO100 IKBKG DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways 13125:[DB04998 DB01019] DB04998|AGRO100 IKBKG DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13126:[DB04998 DB13800] DB04998|AGRO100 IKBKG DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0038095| IKBKG;CALM1 13127:[DB04998 DB08613] DB04998|AGRO100 IKBKG DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;HDAC4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;HDAC4 GO:0006355| regulation of transcription, DNA-dependent IKBKG;HDAC4 GO:0006954| inflammatory response IKBKG;HDAC4 13128:[DB04998 DB01496] DB04998|AGRO100 IKBKG DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13129:[DB04998 DB04948] DB04998|AGRO100 IKBKG DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 13130:[DB04998 DB11637] DB04998|AGRO100 IKBKG DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG 13131:[DB04998 DB13994] DB04998|AGRO100 IKBKG DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 13132:[DB04998 DB00414] DB04998|AGRO100 IKBKG DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways 13133:[DB04998 DB00565] DB04998|AGRO100 IKBKG DB00565|Cisatracurium CHRNA2 common genes common pathways 13134:[DB04998 DB08502] DB04998|AGRO100 IKBKG DB08502|Capravirine CYP3A4 common genes common pathways 13135:[DB04998 DB00494] DB04998|AGRO100 IKBKG DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways 13136:[DB04998 DB01548] DB04998|AGRO100 IKBKG DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TRIM13 GO:0045087| innate immune response IKBKG;TRIM13 GO:0016239| positive regulation of macroautophagy IKBKG;TRIM13 GO:0051092| positive regulation of NF-kappaB transcription factor activity TRIM13;IKBKG GO:0006955| immune response OPRK1;IKBKG;OPRD1 13137:[DB04998 DB06148] DB04998|AGRO100 IKBKG DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0006954| inflammatory response HRH1;HRH4;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0006955| immune response OPRK1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 13138:[DB04998 DB12093] DB04998|AGRO100 IKBKG DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG 13139:[DB04998 DB00315] DB04998|AGRO100 IKBKG DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways 13140:[DB04998 DB11064] DB04998|AGRO100 IKBKG DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent PGR;IKBKG;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG;ESR1;AR GO:0006351| transcription, DNA-dependent PGR;IKBKG;ESR1;AR 13141:[DB04998 DB07720] DB04998|AGRO100 IKBKG DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13142:[DB04998 DB05201] DB04998|AGRO100 IKBKG DB05201|V24343 CNR1 common genes common pathways 13143:[DB04998 DB03566] DB04998|AGRO100 IKBKG DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13144:[DB04998 DB06111] DB04998|AGRO100 IKBKG DB06111|AB192 MPO common genes common pathways 13145:[DB04998 DB01074] DB04998|AGRO100 IKBKG DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways 13146:[DB04998 DB05091] DB04998|AGRO100 IKBKG DB05091|M0002 AVPR2 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;IKBKG 13147:[DB04998 DB06595] DB04998|AGRO100 IKBKG DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0016239| positive regulation of macroautophagy IKBKG;KDR GO:0016032| viral reproduction KDR;PDGFRA;IKBKG GO:0006954| inflammatory response IKBKG;KIT GO:0000187| activation of MAPK activity KIT;IKBKG GO:0006915| apoptotic process IKBKG;PRKCA 13148:[DB04998 DB00790] DB04998|AGRO100 IKBKG DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways 13149:[DB04998 DB01296] DB04998|AGRO100 IKBKG DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NFKB2 GO:0006954| inflammatory response NFKB2;TNF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB2;TNF;IKBKG GO:0006955| immune response IFNG;TNF;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NFKB2 GO:0045087| innate immune response IKBKG;NFKB2 GO:0009615| response to virus IKBKG;TNF;IFNG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB2;TNF;IKBKG GO:0007254| JNK cascade IKBKG;TNF GO:0006915| apoptotic process IFNG;IKBKG GO:0000187| activation of MAPK activity TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;NFKB2;TNF 13150:[DB04998 DB12866] DB04998|AGRO100 IKBKG DB12866|Pradigastat SLC22A8 common genes common pathways 13151:[DB04998 DB00849] DB04998|AGRO100 IKBKG DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13152:[DB04998 DB01412] DB04998|AGRO100 IKBKG DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0006915| apoptotic process IKBKG;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ADORA2A;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;PDE4B GO:0006954| inflammatory response ADORA2A;ADORA1;IKBKG 13153:[DB04998 DB04674] DB04998|AGRO100 IKBKG DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways 13154:[DB04998 DB04827] DB04998|AGRO100 IKBKG DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways 13155:[DB04998 DB00521] DB04998|AGRO100 IKBKG DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13156:[DB04998 DB00549] DB04998|AGRO100 IKBKG DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1 13157:[DB04998 DB00531] DB04998|AGRO100 IKBKG DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 13158:[DB04998 DB05419] DB04998|AGRO100 IKBKG DB05419|ADX-10061 CALY common genes common pathways 13159:[DB04998 DB06700] DB04998|AGRO100 IKBKG DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways 13160:[DB04998 DB00852] DB04998|AGRO100 IKBKG DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;TNF GO:0038095| FOS;IKBKG;JUN;NFATC1 GO:0007254| JNK cascade IKBKG;TNF GO:0000187| activation of MAPK activity IKBKG;TNF GO:0006915| apoptotic process ADRA1A;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0006351| transcription, DNA-dependent JUN;ATF4;NFATC1;ATF1;JDP2;ATF6;ATF3;ATF7;ATF2;ATF5;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFATC1;ATF1;JUN;ADRB2;ATF4;ATF2;IL2;ATF5;IKBKG;TNF;FOS;ATF3;ATF6 GO:0009615| response to virus TNF;IKBKG GO:0006974| response to DNA damage stimulus ATF2;IKBKG GO:0006355| regulation of transcription, DNA-dependent ATF4;JUN;NFATC1;ATF1;ATF3;FOS;ATF6;JDP2;ATF5;IKBKG;ATF2;ATF7 GO:0006955| immune response TNF;IKBKG;IL2 GO:0016032| viral reproduction IKBKG;ATF7 GO:0006954| inflammatory response FOS;TNF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IKBKG 13161:[DB04998 DB05022] DB04998|AGRO100 IKBKG DB05022|Amonafide TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 13162:[DB04998 DB00534] DB04998|AGRO100 IKBKG DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways 13163:[DB04998 DB00229] DB04998|AGRO100 IKBKG DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways 13164:[DB04998 DB05210] DB04998|AGRO100 IKBKG DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0045087| innate immune response PRKDC;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;PRKDC GO:0045944| positive regulation of transcription from RNA polymerase II promoter PIK3R1;IKBKG;PIK3R2;PRKDC GO:0050852| T cell receptor signaling pathway PIK3R2;PIK3R1;IKBKG GO:0043276| anoikis IKBKG;MTOR GO:0016032| viral reproduction IKBKG;PIK3R1 GO:0038095| IKBKG;PIK3R1;PIK3R2 13165:[DB04998 DB01588] DB04998|AGRO100 IKBKG DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG 13166:[DB04998 DB00963] DB04998|AGRO100 IKBKG DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13167:[DB04998 DB00396] DB04998|AGRO100 IKBKG DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0016579| protein deubiquitination IKBKG;AR;ESR1 GO:0006915| apoptotic process NR3C1;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG;PGR;ESR1;NR3C1;AR GO:0006351| transcription, DNA-dependent NR3C1;ESR1;AR;NR1I2;PGR;NR3C2;IKBKG GO:0006954| inflammatory response IKBKG;ORM1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006955| immune response IKBKG;OPRK1 GO:0016032| viral reproduction SLC10A1;IKBKG GO:0006355| regulation of transcription, DNA-dependent PGR;NR3C2;IKBKG;NR1I2;AR;NR3C1;ESR1 13168:[DB04998 DB06138] DB04998|AGRO100 IKBKG DB06138|IRL-1620 EDNRB common genes common pathways 13169:[DB04998 DB00289] DB04998|AGRO100 IKBKG DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 13170:[DB04998 DB00946] DB04998|AGRO100 IKBKG DB00946|Phenprocoumon VKORC1;CYP2C8;CYP2C9;CYP3A4;ALB;ORM1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG 13171:[DB04998 DB06751] DB04998|AGRO100 IKBKG DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways 13172:[DB04998 DB04926] DB04998|AGRO100 IKBKG DB04926|Neramexane GRIN3A common genes common pathways 13173:[DB04998 DB01650] DB04998|AGRO100 IKBKG DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways 13174:[DB04998 DB05521] DB04998|AGRO100 IKBKG DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG 13175:[DB04998 DB01257] DB04998|AGRO100 IKBKG DB01257|Eculizumab C5 common genes common pathways GO:0045087| innate immune response C5;IKBKG GO:0006954| inflammatory response C5;IKBKG GO:0000187| activation of MAPK activity C5;IKBKG 13176:[DB04998 DB00150] DB04998|AGRO100 IKBKG DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0006954| inflammatory response IKBKG;IDO1 13177:[DB04998 DB12035] DB04998|AGRO100 IKBKG DB12035|Sarecycline ABCB1 common genes common pathways 13178:[DB04998 DB01288] DB04998|AGRO100 IKBKG DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13179:[DB04998 DB08827] DB04998|AGRO100 IKBKG DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways 13180:[DB04998 DB06155] DB04998|AGRO100 IKBKG DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways 13181:[DB04998 DB06274] DB04998|AGRO100 IKBKG DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0006955| immune response OPRK1;IKBKG;OPRD1 13182:[DB04998 DB11431] DB04998|AGRO100 IKBKG DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways 13183:[DB04998 DB06292] DB04998|AGRO100 IKBKG DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 13184:[DB04998 DB00715] DB04998|AGRO100 IKBKG DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0009615| response to virus CHRM2;IKBKG 13185:[DB04998 DB05688] DB04998|AGRO100 IKBKG DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways 13186:[DB04998 DB00567] DB04998|AGRO100 IKBKG DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways 13187:[DB04998 DB01483] DB04998|AGRO100 IKBKG DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 13188:[DB04998 DB06579] DB04998|AGRO100 IKBKG DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways 13189:[DB04998 DB00834] DB04998|AGRO100 IKBKG DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;PGR;IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;NR1I2;PGR;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG;PGR;NR3C1 13190:[DB04998 DB14069] DB04998|AGRO100 IKBKG DB14069|ONT-093 ABCB1 common genes common pathways 13191:[DB04998 DB01551] DB04998|AGRO100 IKBKG DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways 13192:[DB04998 DB00978] DB04998|AGRO100 IKBKG DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 13193:[DB04998 DB05034] DB04998|AGRO100 IKBKG DB05034|Ularitide NPR1 common genes common pathways 13194:[DB04998 DB06603] DB04998|AGRO100 IKBKG DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;HDAC1;HDAC4;HDAC3;HDAC2;HDAC5 GO:0006351| transcription, DNA-dependent HDAC2;HDAC8;HDAC5;HDAC9;HDAC3;HDAC10;HDAC6;HDAC7;HDAC11;IKBKG;HDAC4;HDAC1 GO:0016032| viral reproduction HDAC1;IKBKG GO:0006954| inflammatory response IKBKG;HDAC4;HDAC5;HDAC9 GO:0006355| regulation of transcription, DNA-dependent IKBKG;HDAC4;HDAC1;HDAC10;HDAC5;HDAC2;HDAC8;HDAC9;HDAC3;HDAC11;HDAC7;HDAC6 13195:[DB04998 DB09030] DB04998|AGRO100 IKBKG DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade F2R;IKBKG GO:0006954| inflammatory response F2R;IKBKG 13196:[DB04998 DB06342] DB04998|AGRO100 IKBKG DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways 13197:[DB04998 DB04299] DB04998|AGRO100 IKBKG DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0016032| viral reproduction TPR;IKBKG 13198:[DB04998 DB09108] DB04998|AGRO100 IKBKG DB09108|Simoctocog Alfa VWF common genes common pathways 13199:[DB04998 DB00537] DB04998|AGRO100 IKBKG DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 13200:[DB04998 DB00713] DB04998|AGRO100 IKBKG DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways 13201:[DB04998 DB14055] DB04998|AGRO100 IKBKG DB14055|(S)-Warfarin CYP3A4;CYP2C8;CYP2C9;CYP2C18;CYP2C19 common genes common pathways 13202:[DB04998 DB00305] DB04998|AGRO100 IKBKG DB00305|Mitomycin POR common genes common pathways 13203:[DB04998 DB01047] DB04998|AGRO100 IKBKG DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;SMO;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG 13204:[DB04998 DB00501] DB04998|AGRO100 IKBKG DB00501|Cimetidine HRH2;CYP1A2;CYP2C19;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP11B1;CYP2C8;CYP2C9;CYP2E1;FMO3;FMO1;ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A6;SLC22A8;SLC47A1;SLC22A4;SLC22A11;SLC22A7;ABCB11;SLC47A2 common genes common pathways GO:0006955| immune response IKBKG;CYP11B1;HRH2 13205:[DB04998 DB00619] DB04998|AGRO100 IKBKG DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;KIT GO:0006915| apoptotic process IKBKG;ABL1 GO:0045087| innate immune response CSF1R;ABL1;IKBKG GO:0006974| response to DNA damage stimulus ABL1;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ABL1 GO:0006954| inflammatory response ORM1;IKBKG;KIT;CSF1R;PTGS1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NTRK1;IKBKG GO:0016032| viral reproduction PDGFRA;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ABL1 GO:1901215| NTRK1;IKBKG 13206:[DB04998 DB01263] DB04998|AGRO100 IKBKG DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways 13207:[DB04998 DB08882] DB04998|AGRO100 IKBKG DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways 13208:[DB04998 DB08900] DB04998|AGRO100 IKBKG DB08900|Teduglutide GLP2R common genes common pathways 13209:[DB04998 DB13167] DB04998|AGRO100 IKBKG DB13167|Alclofenac PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2 13210:[DB04998 DB00182] DB04998|AGRO100 IKBKG DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG;DRD2 GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 13211:[DB04998 DB00921] DB04998|AGRO100 IKBKG DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0006955| immune response OPRD1;IKBKG;OPRK1 13212:[DB04998 DB01590] DB04998|AGRO100 IKBKG DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0043276| anoikis MTOR;IKBKG 13213:[DB04998 DB00661] DB04998|AGRO100 IKBKG DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0050852| T cell receptor signaling pathway IKBKG;CACNB3 GO:0006915| apoptotic process IKBKG;ADRA1A 13214:[DB04998 DB01367] DB04998|AGRO100 IKBKG DB01367|Rasagiline MAOB;BCL2;CYP1A2 common genes common pathways GO:0006974| response to DNA damage stimulus BCL2;IKBKG GO:0006915| apoptotic process IKBKG;BCL2 13215:[DB04998 DB01307] DB04998|AGRO100 IKBKG DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;INSR GO:0000187| activation of MAPK activity INSR;IKBKG 13216:[DB04998 DB01571] DB04998|AGRO100 IKBKG DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response OPRK1;IKBKG;OPRD1 13217:[DB04998 DB00353] DB04998|AGRO100 IKBKG DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG 13218:[DB04998 DB01408] DB04998|AGRO100 IKBKG DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination ADRB2;IKBKG 13219:[DB04998 DB08820] DB04998|AGRO100 IKBKG DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0016579| protein deubiquitination IKBKG;CFTR 13220:[DB04998 DB00324] DB04998|AGRO100 IKBKG DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006915| apoptotic process NR3C1;IKBKG 13221:[DB04998 DB04938] DB04998|AGRO100 IKBKG DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ESR1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR1 GO:0016579| protein deubiquitination IKBKG;ESR1 13222:[DB04998 DB13878] DB04998|AGRO100 IKBKG DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 13223:[DB04998 DB13961] DB04998|AGRO100 IKBKG DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB2;IKBKG;NFKB1 GO:0038095| NFKB1;IKBKG GO:0006915| apoptotic process NFKB1;PPARD;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter SREBF1;IKBKG;NFKB2;PPARG;NFKB1;PPARA GO:0045087| innate immune response NFKB1;IKBKG;NFKB2;PPARG GO:0002223| stimulatory C-type lectin receptor signaling pathway NFKB1;IKBKG GO:0051403| stress-activated MAPK cascade NFKB1;IKBKG GO:0006351| transcription, DNA-dependent PPARA;PPARD;NFKB1;PPARG;NFKB2;IKBKG;SREBF1 GO:0006954| inflammatory response NFKB2;IKBKG;PTGS2;NFKB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;IKBKG;NFKB2 GO:0006355| regulation of transcription, DNA-dependent NFKB1;PPARD;PPARA;SREBF1;IKBKG;PPARG;NFKB2 GO:0050852| T cell receptor signaling pathway NFKB1;IKBKG;CACNB3 GO:1901215| PPARA;IKBKG 13224:[DB04998 DB00261] DB04998|AGRO100 IKBKG DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways 13225:[DB04998 DB00444] DB04998|AGRO100 IKBKG DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 13226:[DB04998 DB01098] DB04998|AGRO100 IKBKG DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways 13227:[DB04998 DB01236] DB04998|AGRO100 IKBKG DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;IKBKG 13228:[DB04998 DB09481] DB04998|AGRO100 IKBKG DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 13229:[DB04998 DB13954] DB04998|AGRO100 IKBKG DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0016579| protein deubiquitination BECN1;IKBKG;ESR1 GO:0006915| apoptotic process BECN1;IKBKG;GPER1 GO:0006954| inflammatory response GPER1;IKBKG GO:0016032| viral reproduction BECN1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I2;NCOA2;IKBKG;ESR2;ESRRG GO:0045087| innate immune response GPER1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GPER1;ESR1;ESRRG;ESR2;IKBKG;NCOA2;NR1I2 GO:0009615| response to virus CYP1A1;IKBKG GO:0006351| transcription, DNA-dependent ESR1;ESRRG;IKBKG;ESR2;NCOA2;NR1I2 13230:[DB04998 DB04365] DB04998|AGRO100 IKBKG DB04365|Arecoline CHRM1;CHRM3 common genes common pathways 13231:[DB04998 DB01593] DB04998|AGRO100 IKBKG DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:1901215| APP;APOE;IKBKG;MT3 GO:0006355| regulation of transcription, DNA-dependent ENO1;TP73;IKBKG;TP53;HDAC1;EEF1A1;HDAC4;HDAC8;INS;PARP1;ESR1 GO:0016032| viral reproduction SIVA1;HDAC1;IDE;MDM2;TP53;APOA2;IKBKG;CFH;TP73 GO:0006955| immune response IL3;IGHA1;C1QC;C3;VTN;IGLV3-21;C8A;IGKV1-17;IKBKG;JCHAIN;C8B;C1R GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;APP;CLU;INS;AGT;S100A9;S100A8 GO:0006954| inflammatory response KRT16;HDAC4;BDKRB1;IKBKG;SERPINA3;KNG1;C5;C3;KLKB1;S100A8;S100A9;C4B GO:0006351| transcription, DNA-dependent HDAC8;ESR1;PARP1;IKBKG;TP73;ENO1;HDAC4;HDAC1;EEF1A1;TP53 GO:0051403| stress-activated MAPK cascade IKBKG;AGT GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;PDIA3 GO:0006974| response to DNA damage stimulus TP53;TP73;IKBKG;BRCC3;PARP1;MGMT;MPG GO:0045087| innate immune response JCHAIN;CFB;IKBKG;FGA;FCN3;CFH;IGHM;S100A7;KRT16;C8B;C1QB;APP;C1R;CLU;C4BPA;PGLYRP2;C4B;C8G;C1QC;CFI;C3;IGHA1;C5;C1S;APCS;C4BPB;S100A9;C8A;F12;APOL1;S100A8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;ESR1;TP53;APP;HDAC1;HDAC4;TP73;IKBKG GO:0009615| response to virus CLU;IKBKG;ENO1 GO:0000187| activation of MAPK activity C5;SOD1;IKBKG;TP73;APP GO:0006915| apoptotic process CLU;TP53;APP;APLP1;TP73;PDCD6;IKBKG;GSN;S100A8;PARP1;S100A9;SIVA1;MT3 GO:0038095| IGLV3-21;IKBKG;IGKV1-17 GO:0016579| protein deubiquitination BRCC3;ESR1;IKBKG;MDM2;TP53 13232:[DB04998 DB00075] DB04998|AGRO100 IKBKG DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;CD3D GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response C1R;C1QB;IKBKG;FCGR1A;C1S;C1QC;C1QA GO:0050852| T cell receptor signaling pathway CD247;CD3E;IKBKG;CD3D;CD3G GO:0006955| immune response C1QC;FCGR2C;FCGR3A;FCGR3B;FCGR2B;C1R;FCGR1A;IKBKG GO:0016032| viral reproduction CD247;IKBKG;FCGR2B GO:0006954| inflammatory response FCGR2B;IKBKG 13233:[DB04998 DB09063] DB04998|AGRO100 IKBKG DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity ALK;IKBKG GO:0000187| activation of MAPK activity IKBKG;ALK 13234:[DB04998 DB00607] DB04998|AGRO100 IKBKG DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways 13235:[DB04998 DB05932] DB04998|AGRO100 IKBKG DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;VEGFA 13236:[DB04998 DB06786] DB04998|AGRO100 IKBKG DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;SMO 13237:[DB04998 DB00514] DB04998|AGRO100 IKBKG DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 GO:0006915| apoptotic process NCF1;IKBKG GO:0038095| RAC1;IKBKG GO:0045087| innate immune response NCF1;CYBA;NCF2;CYBB;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent NCF1;NCF4;CYBA;NCF2;CYBB;IKBKG GO:0006954| inflammatory response CYBA;CYBB;IKBKG;RAC1 GO:0006955| immune response OPRK1;IKBKG;NCF4;OPRD1 13238:[DB04998 DB01101] DB04998|AGRO100 IKBKG DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways 13239:[DB04998 DB13141] DB04998|AGRO100 IKBKG DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 13240:[DB04998 DB13867] DB04998|AGRO100 IKBKG DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways 13241:[DB04998 DB01275] DB04998|AGRO100 IKBKG DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways GO:0006954| inflammatory response AOC3;IKBKG 13242:[DB04998 DB12092] DB04998|AGRO100 IKBKG DB12092|Naftopidil CYP3A4 common genes common pathways 13243:[DB04998 DB01327] DB04998|AGRO100 IKBKG DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006955| immune response IL15;IL2;IKBKG GO:0006954| inflammatory response IL15;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;IL2 13244:[DB04998 DB07280] DB04998|AGRO100 IKBKG DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 13245:[DB04998 DB00342] DB04998|AGRO100 IKBKG DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG GO:0006954| inflammatory response HRH1;IKBKG 13246:[DB04998 DB00398] DB04998|AGRO100 IKBKG DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0016239| positive regulation of macroautophagy IKBKG;KDR GO:0016032| viral reproduction KDR;IKBKG GO:0006954| inflammatory response KIT;IKBKG GO:0050852| T cell receptor signaling pathway BRAF;IKBKG GO:0006355| regulation of transcription, DNA-dependent FGFR1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;RAF1 GO:0006351| transcription, DNA-dependent IKBKG;FGFR1 GO:0002223| stimulatory C-type lectin receptor signaling pathway RAF1;IKBKG GO:0000187| activation of MAPK activity KIT;IKBKG GO:0006915| apoptotic process RAF1;IKBKG 13247:[DB04998 DB14061] DB04998|AGRO100 IKBKG DB14061|Hycanthone ABCB1 common genes common pathways 13248:[DB04998 DB00112] DB04998|AGRO100 IKBKG DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;VEGFA GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response C1R;C1QB;FCGR1A;IKBKG;C1QC;C1QA GO:0006955| immune response C1QC;FCGR3A;FCGR2C;FCGR2B;FCGR3B;C1R;IKBKG;FCGR1A GO:0016032| viral reproduction IKBKG;FCGR2B GO:0006954| inflammatory response IKBKG;FCGR2B 13249:[DB04998 DB09034] DB04998|AGRO100 IKBKG DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways 13250:[DB04998 DB01242] DB04998|AGRO100 IKBKG DB01242|Clomipramine SLC6A4;HTR2A;HTR2B;HTR2C;SLC6A2;GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;ALB;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B 13251:[DB04998 DB06458] DB04998|AGRO100 IKBKG DB06458|Remacemide CYP3A4 common genes common pathways 13252:[DB04998 DB00470] DB04998|AGRO100 IKBKG DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 GO:0006954| inflammatory response PTGS1;CNR2;IKBKG GO:0006955| immune response CNR2;IKBKG 13253:[DB04998 DB01336] DB04998|AGRO100 IKBKG DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13254:[DB04998 DB06655] DB04998|AGRO100 IKBKG DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways 13255:[DB04998 DB04539] DB04998|AGRO100 IKBKG DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways 13256:[DB04998 DB00559] DB04998|AGRO100 IKBKG DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways 13257:[DB04998 DB00823] DB04998|AGRO100 IKBKG DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0016579| protein deubiquitination ESR1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PGR;IKBKG GO:0006351| transcription, DNA-dependent ESR1;PGR;IKBKG 13258:[DB04998 DB05372] DB04998|AGRO100 IKBKG DB05372|CP-945598 CNR1 common genes common pathways 13259:[DB04998 DB01154] DB04998|AGRO100 IKBKG DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways 13260:[DB04998 DB01356] DB04998|AGRO100 IKBKG DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:1901215| IKBKG;GSK3B 13261:[DB04998 DB06779] DB04998|AGRO100 IKBKG DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;VEGFA GO:0006954| inflammatory response SELP;IKBKG 13262:[DB04998 DB05501] DB04998|AGRO100 IKBKG DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0009615| response to virus CXCR4;IKBKG GO:0006955| immune response IKBKG;CCR5 GO:0016032| viral reproduction CXCR4;IKBKG;CCR5 GO:0006954| inflammatory response CXCR4;IKBKG;CCR5 GO:0000187| activation of MAPK activity CXCR4;IKBKG GO:0006915| apoptotic process CXCR4;IKBKG 13263:[DB04998 DB06702] DB04998|AGRO100 IKBKG DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 13264:[DB04998 DB01426] DB04998|AGRO100 IKBKG DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG 13265:[DB04998 DB00462] DB04998|AGRO100 IKBKG DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13266:[DB04998 DB04850] DB04998|AGRO100 IKBKG DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways 13267:[DB04998 DB00351] DB04998|AGRO100 IKBKG DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG;PGR GO:0006351| transcription, DNA-dependent IKBKG;PGR;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 13268:[DB04998 DB04858] DB04998|AGRO100 IKBKG DB04858|Tirapazamine CYP2E1 common genes common pathways 13269:[DB04998 DB11672] DB04998|AGRO100 IKBKG DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0006351| transcription, DNA-dependent VDR;PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;IKBKG;PPARG GO:0045087| innate immune response IKBKG;PPARG GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG;VDR 13270:[DB04998 DB02032] DB04998|AGRO100 IKBKG DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 13271:[DB04998 DB00668] DB04998|AGRO100 IKBKG DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0007254| JNK cascade IKBKG;TNF GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity ADRA2B;TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0006955| immune response TNF;IKBKG GO:0006954| inflammatory response TNF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TNF GO:0009615| response to virus TNF;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNF 13272:[DB04998 DB09295] DB04998|AGRO100 IKBKG DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13273:[DB04998 DB00328] DB04998|AGRO100 IKBKG DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes common pathways GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;IKBKG;PPARG GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG GO:0016032| viral reproduction SLC10A1;IKBKG GO:0006955| immune response PTGDR2;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PPARG;PPARA GO:0045087| innate immune response IKBKG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;IKBKG 13274:[DB04998 DB00394] DB04998|AGRO100 IKBKG DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG 13275:[DB04998 DB00286] DB04998|AGRO100 IKBKG DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;ESR1 GO:0016032| viral reproduction SLC10A1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG 13276:[DB04998 DB00811] DB04998|AGRO100 IKBKG DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0006955| immune response ENPP1;IKBKG 13277:[DB04998 DB05395] DB04998|AGRO100 IKBKG DB05395|Amibegron ADRB3 common genes common pathways 13278:[DB04998 DB00577] DB04998|AGRO100 IKBKG DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways 13279:[DB04998 DB01397] DB04998|AGRO100 IKBKG DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG 13280:[DB04998 DB01017] DB04998|AGRO100 IKBKG DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0006915| apoptotic process CASP1;IL1B;IKBKG;CYCS;CASP3 GO:0000187| activation of MAPK activity IKBKG;IL1B GO:0006955| immune response IL1B;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;IKBKG GO:0006954| inflammatory response ALOX5;IKBKG;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;IL1B;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;CASP3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;IKBKG;CASP1 13281:[DB04998 DB01149] DB04998|AGRO100 IKBKG DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A GO:0016032| viral reproduction HTR2A;IKBKG 13282:[DB04998 DB05478] DB04998|AGRO100 IKBKG DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways 13283:[DB04998 DB11582] DB04998|AGRO100 IKBKG DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TNFSF11 GO:0006955| immune response TNFSF11;IKBKG GO:1901215| IKBKG;GABRB2;GABRB3 13284:[DB04998 DB06081] DB04998|AGRO100 IKBKG DB06081|Caplacizumab VWF common genes common pathways 13285:[DB04998 DB01190] DB04998|AGRO100 IKBKG DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways 13286:[DB04998 DB00982] DB04998|AGRO100 IKBKG DB00982|Isotretinoin RARA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;RARA GO:0006351| transcription, DNA-dependent IKBKG;RARA GO:0006355| regulation of transcription, DNA-dependent IKBKG;RARA 13287:[DB04998 DB04817] DB04998|AGRO100 IKBKG DB04817|Metamizole PTGS1;CYP2B6;CYP3A4 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1 13288:[DB04998 DB00202] DB04998|AGRO100 IKBKG DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG GO:0009615| response to virus IKBKG;CHRM2 13289:[DB04998 DB13178] DB04998|AGRO100 IKBKG DB13178|Inositol SLC5A3 common genes common pathways 13290:[DB04998 DB01364] DB04998|AGRO100 IKBKG DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 13291:[DB04998 DB06697] DB04998|AGRO100 IKBKG DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways 13292:[DB04998 DB01095] DB04998|AGRO100 IKBKG DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13293:[DB04998 DB14063] DB04998|AGRO100 IKBKG DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways 13294:[DB04998 DB04953] DB04998|AGRO100 IKBKG DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways 13295:[DB04998 DB06707] DB04998|AGRO100 IKBKG DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B 13296:[DB04998 DB09143] DB04998|AGRO100 IKBKG DB09143|Sonidegib SMO;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter SMO;IKBKG 13297:[DB04998 DB00293] DB04998|AGRO100 IKBKG DB00293|Raltitrexed TYMS;FPGS common genes common pathways 13298:[DB04998 DB00320] DB04998|AGRO100 IKBKG DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG 13299:[DB04998 DB00835] DB04998|AGRO100 IKBKG DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0006954| inflammatory response HRH1;IKBKG GO:0009615| response to virus IKBKG;CHRM2 13300:[DB04998 DB00576] DB04998|AGRO100 IKBKG DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways 13301:[DB04998 DB01213] DB04998|AGRO100 IKBKG DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IKBKG 13302:[DB04998 DB00718] DB04998|AGRO100 IKBKG DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NME2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NME2 GO:0006351| transcription, DNA-dependent IKBKG;NME2 13303:[DB04998 DB00368] DB04998|AGRO100 IKBKG DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;POU5F1 GO:0006351| transcription, DNA-dependent IKBKG;POU5F1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2;POU5F1 GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 13304:[DB04998 DB02751] DB04998|AGRO100 IKBKG DB02751|Glycocyamine GAMT common genes common pathways 13305:[DB04998 DB09038] DB04998|AGRO100 IKBKG DB09038|Empagliflozin SLC5A2 common genes common pathways 13306:[DB04998 DB00074] DB04998|AGRO100 IKBKG DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response IKBKG;FCGR1A;C1R;C1QB;C1QA;C1S;C1QC GO:0006955| immune response FCGR2B;FCGR3B;C1R;IKBKG;FCGR1A;C1QC;IL2RA;FCGR3A;FCGR2C GO:0016032| viral reproduction FCGR2B;IL2RB;IKBKG GO:0006954| inflammatory response FCGR2B;IKBKG;IL2RA GO:0006915| apoptotic process IL2RA;IKBKG 13307:[DB04998 DB00755] DB04998|AGRO100 IKBKG DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes common pathways GO:0016032| viral reproduction IKBKG;RXRA GO:0006954| inflammatory response CYP26B1;IKBKG GO:0006355| regulation of transcription, DNA-dependent RXRA;RXRB;RXRG;IKBKG;RARB;NR0B1;RARG;CRABP2;RARA GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;RARA;RXRA;RXRB;RXRG;IKBKG;RARB GO:0006351| transcription, DNA-dependent RARG;RARA;IKBKG;RXRG;NR0B1;RARB;RXRB;RXRA 13308:[DB04998 DB00749] DB04998|AGRO100 IKBKG DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 GO:0016032| viral reproduction RXRA;IKBKG GO:0006355| regulation of transcription, DNA-dependent RXRA;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;RXRA 13309:[DB04998 DB03128] DB04998|AGRO100 IKBKG DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13310:[DB04998 DB01306] DB04998|AGRO100 IKBKG DB01306|Insulin Aspart INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;INSR GO:0000187| activation of MAPK activity IKBKG;INSR 13311:[DB04998 DB14570] DB04998|AGRO100 IKBKG DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways 13312:[DB04998 DB05773] DB04998|AGRO100 IKBKG DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ERBB2;IKBKG GO:0006351| transcription, DNA-dependent ERBB2;IKBKG 13313:[DB04998 DB00148] DB04998|AGRO100 IKBKG DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways 13314:[DB04998 DB01614] DB04998|AGRO100 IKBKG DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 13315:[DB04998 DB13151] DB04998|AGRO100 IKBKG DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0045087| innate immune response FGB;FGA;IKBKG 13316:[DB04998 DB00475] DB04998|AGRO100 IKBKG DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:1901215| GABRB2;IKBKG;GABRB3 13317:[DB04998 DB01431] DB04998|AGRO100 IKBKG DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR;ESR1 GO:0006351| transcription, DNA-dependent IKBKG;PGR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG;ESR1 GO:0016579| protein deubiquitination IKBKG;ESR1 13318:[DB04998 DB01610] DB04998|AGRO100 IKBKG DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways 13319:[DB04998 DB01382] DB04998|AGRO100 IKBKG DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways 13320:[DB04998 DB08836] DB04998|AGRO100 IKBKG DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways 13321:[DB04998 DB00714] DB04998|AGRO100 IKBKG DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG 13322:[DB04998 DB01600] DB04998|AGRO100 IKBKG DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG 13323:[DB04998 DB09099] DB04998|AGRO100 IKBKG DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways 13324:[DB04998 DB06699] DB04998|AGRO100 IKBKG DB06699|Degarelix GNRHR common genes common pathways 13325:[DB04998 DB00176] DB04998|AGRO100 IKBKG DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13326:[DB04998 DB06822] DB04998|AGRO100 IKBKG DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0006955| immune response CXCL12;IKBKG GO:0009615| response to virus IKBKG;CXCL12 13327:[DB04998 DB00200] DB04998|AGRO100 IKBKG DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways 13328:[DB04998 DB09564] DB04998|AGRO100 IKBKG DB09564|Insulin Degludec INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent INSR;IKBKG GO:0000187| activation of MAPK activity INSR;IKBKG 13329:[DB04998 DB14517] DB04998|AGRO100 IKBKG DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0006915| apoptotic process APP;IKBKG GO:0000187| activation of MAPK activity APP;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;IKBKG GO:0045087| innate immune response APP;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;IKBKG GO:1901215| APP;IKBKG 13330:[DB04998 DB01212] DB04998|AGRO100 IKBKG DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 13331:[DB04998 DB11921] DB04998|AGRO100 IKBKG DB11921|Deflazacort CYP3A4 common genes common pathways 13332:[DB04998 DB01289] DB04998|AGRO100 IKBKG DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways 13333:[DB04998 DB00762] DB04998|AGRO100 IKBKG DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes common pathways GO:0016032| viral reproduction TOP1;IKBKG 13334:[DB04998 DB00357] DB04998|AGRO100 IKBKG DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways 13335:[DB04998 DB00243] DB04998|AGRO100 IKBKG DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways GO:0006954| inflammatory response SCN9A;IKBKG 13336:[DB04998 DB06191] DB04998|AGRO100 IKBKG DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways 13337:[DB04998 DB00884] DB04998|AGRO100 IKBKG DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0016032| viral reproduction FDPS;IKBKG GO:0006954| inflammatory response IKBKG;PTGS2 13338:[DB04998 DB01014] DB04998|AGRO100 IKBKG DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0006954| inflammatory response IKBKG;ALOX5;PTGS1;PTGS2 GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARG GO:0045087| innate immune response IKBKG;PPARG GO:0006351| transcription, DNA-dependent PPARG;IKBKG 13339:[DB04998 DB04334] DB04998|AGRO100 IKBKG DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0006954| inflammatory response AOC3;IKBKG 13340:[DB04998 DB09309] DB04998|AGRO100 IKBKG DB09309|Kitasamycin CYP3A4 common genes common pathways 13341:[DB04998 DB00993] DB04998|AGRO100 IKBKG DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways GO:0006954| inflammatory response IKBKG;RAC1 GO:0038095| RAC1;IKBKG 13342:[DB04998 DB01056] DB04998|AGRO100 IKBKG DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways 13343:[DB04998 DB00555] DB04998|AGRO100 IKBKG DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0006915| apoptotic process ADORA2A;ADRA1A;IKBKG GO:0006955| immune response OPRK1;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0006954| inflammatory response HRH1;ADORA1;ADORA2A;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ADORA2A GO:1901215| GABRB3;IKBKG;GABRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0009615| response to virus CHRM2;IKBKG 13344:[DB04998 DB11077] DB04998|AGRO100 IKBKG DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0006955| immune response ENPP1;IKBKG 13345:[DB04998 DB11487] DB04998|AGRO100 IKBKG DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways 13346:[DB04998 DB04896] DB04998|AGRO100 IKBKG DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 13347:[DB04998 DB01354] DB04998|AGRO100 IKBKG DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 13348:[DB04998 DB01255] DB04998|AGRO100 IKBKG DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways 13349:[DB04998 DB01253] DB04998|AGRO100 IKBKG DB01253|Ergometrine ADRA1A;CYP3A4;ABCB1 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 13350:[DB04998 DB01202] DB04998|AGRO100 IKBKG DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways 13351:[DB04998 DB00344] DB04998|AGRO100 IKBKG DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways 13352:[DB04998 DB00007] DB04998|AGRO100 IKBKG DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways 13353:[DB04998 DB06420] DB04998|AGRO100 IKBKG DB06420|Annamycin TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus IKBKG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 13354:[DB04998 DB09238] DB04998|AGRO100 IKBKG DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0050852| T cell receptor signaling pathway IKBKG;CACNB3 GO:0009615| response to virus IKBKG;CYP1A1 13355:[DB04998 DB00301] DB04998|AGRO100 IKBKG DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways 13356:[DB04998 DB04835] DB04998|AGRO100 IKBKG DB04835|Maraviroc CCR5;CYP3A4 common genes common pathways GO:0016032| viral reproduction CCR5;IKBKG GO:0006955| immune response IKBKG;CCR5 GO:0006954| inflammatory response IKBKG;CCR5 13357:[DB04998 DB00255] DB04998|AGRO100 IKBKG DB00255|Diethylstilbestrol ESR1;ESRRG;ESR2;ESRRA;ESRRB;NCOA2;NR1I2;AR;SHBG;COMT;CYP19A1;CYP3A4;CYP2C8;CYP2C9;CYP2E1;TTR;ABCG2;ABCB1;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;NR1I2;ESRRG;IKBKG;ESRRA;ESR2;ESRRB;ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006351| transcription, DNA-dependent AR;ESR1;ESR2;ESRRB;IKBKG;ESRRA;ESRRG;NR1I2;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;NR1I2;NCOA2;ESR2;ESRRB;ESRRA;IKBKG;ESRRG GO:0016579| protein deubiquitination IKBKG;ESR1;AR 13358:[DB04998 DB00455] DB04998|AGRO100 IKBKG DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 13359:[DB04998 DB05077] DB04998|AGRO100 IKBKG DB05077|SLV319 CNR1 common genes common pathways 13360:[DB04998 DB06963] DB04998|AGRO100 IKBKG DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways 13361:[DB04998 DB00893] DB04998|AGRO100 IKBKG DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0006955| immune response IKBKG;FTH1 13362:[DB04998 DB13874] DB04998|AGRO100 IKBKG DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways 13363:[DB04998 DB06802] DB04998|AGRO100 IKBKG DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13364:[DB04998 DB01764] DB04998|AGRO100 IKBKG DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways 13365:[DB04998 DB06144] DB04998|AGRO100 IKBKG DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 GO:0016032| viral reproduction IKBKG;HTR2A GO:0006915| apoptotic process ADRA1A;IKBKG 13366:[DB04998 DB00797] DB04998|AGRO100 IKBKG DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0006954| inflammatory response IKBKG;HRH1 GO:0006955| immune response IKBKG;HRH2 13367:[DB04998 DB14072] DB04998|AGRO100 IKBKG DB14072|Reversin 121 ABCB1 common genes common pathways 13368:[DB04998 DB01136] DB04998|AGRO100 IKBKG DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes common pathways GO:0006915| apoptotic process GJA1;ADRA1A;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0016579| protein deubiquitination HIF1A;ADRB2;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;HIF1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;GJA1 GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;ADRB2;HIF1A;IKBKG GO:0006355| regulation of transcription, DNA-dependent HIF1A;IKBKG GO:0016239| positive regulation of macroautophagy HIF1A;IKBKG GO:0016032| viral reproduction IKBKG;VCAM1 GO:0006954| inflammatory response SELE;PTGS1;IKBKG 13369:[DB04998 DB00717] DB04998|AGRO100 IKBKG DB00717|Norethisterone PGR;CYP3A4;CYP3A5;CYP3A7;CYP2C19;ALB;SHBG;ABCB1 common genes common pathways GO:0006351| transcription, DNA-dependent PGR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR GO:0006355| regulation of transcription, DNA-dependent PGR;IKBKG 13370:[DB04998 DB01621] DB04998|AGRO100 IKBKG DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG 13371:[DB04998 DB11471] DB04998|AGRO100 IKBKG DB11471|Tilmicosin CYP3A4 common genes common pathways 13372:[DB04998 DB04844] DB04998|AGRO100 IKBKG DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG 13373:[DB04998 DB00425] DB04998|AGRO100 IKBKG DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1 GO:1901215| IKBKG;GABRB3 13374:[DB04998 DB11278] DB04998|AGRO100 IKBKG DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0006915| apoptotic process IKBKG;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13375:[DB04998 DB14502] DB04998|AGRO100 IKBKG DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction SLC20A2;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;SLC20A1 13376:[DB04998 DB03542] DB04998|AGRO100 IKBKG DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 13377:[DB04998 DB11979] DB04998|AGRO100 IKBKG DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways 13378:[DB04998 DB06510] DB04998|AGRO100 IKBKG DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARA;IKBKG;PPARG GO:1901215| PPARA;IKBKG GO:0006351| transcription, DNA-dependent PPARA;PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;IKBKG GO:0045087| innate immune response PPARG;IKBKG 13379:[DB04998 DB07776] DB04998|AGRO100 IKBKG DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ESRRA;ESRRB GO:0006351| transcription, DNA-dependent ESRRA;IKBKG;ESRRB GO:0006355| regulation of transcription, DNA-dependent ESRRB;ESRRA;IKBKG 13380:[DB04998 DB00922] DB04998|AGRO100 IKBKG DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways 13381:[DB04998 DB01176] DB04998|AGRO100 IKBKG DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 13382:[DB04998 DB00962] DB04998|AGRO100 IKBKG DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0006915| apoptotic process IKBKG;TSPO 13383:[DB04998 DB09328] DB04998|AGRO100 IKBKG DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent FADS1;IKBKG 13384:[DB04998 DB01026] DB04998|AGRO100 IKBKG DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0016579| protein deubiquitination AR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006955| immune response IKBKG;CYP11B1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG;NR1I3;AR GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;NR1I3;IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG;NR1I3;AR 13385:[DB04998 DB00784] DB04998|AGRO100 IKBKG DB00784|Mefenamic acid PTGS2;PTGS1;CYP2C9;CYP2C8;UGT1A9;ALB common genes common pathways GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG 13386:[DB04998 DB11751] DB04998|AGRO100 IKBKG DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways 13387:[DB04998 DB01203] DB04998|AGRO100 IKBKG DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13388:[DB04998 DB04911] DB04998|AGRO100 IKBKG DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways 13389:[DB04998 DB01048] DB04998|AGRO100 IKBKG DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0006955| immune response IKBKG;HLA-B GO:0016032| viral reproduction IKBKG;HLA-B GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;HLA-B GO:0045087| innate immune response IKBKG;HLA-B 13390:[DB04998 DB06228] DB04998|AGRO100 IKBKG DB06228|Rivaroxaban F10;CYP3A4;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways 13391:[DB04998 DB11090] DB04998|AGRO100 IKBKG DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;MUC1 13392:[DB04998 DB01097] DB04998|AGRO100 IKBKG DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;AHR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;IKBKG GO:0045087| innate immune response IKBKG;PTK2B GO:0006351| transcription, DNA-dependent AHR;IKBKG GO:0006915| apoptotic process AHR;PTK2B;IKBKG 13393:[DB04998 DB00670] DB04998|AGRO100 IKBKG DB00670|Pirenzepine CHRM1 common genes common pathways 13394:[DB04998 DB01169] DB04998|AGRO100 IKBKG DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent JUN;PML;IKBKG;MAPK1;HDAC1;CCND1 GO:1901215| IKBKG;AKT1 GO:0050852| T cell receptor signaling pathway IKBKB;IKBKG;MAPK1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;IKBKB GO:0043276| anoikis AKT1;IKBKG GO:0006954| inflammatory response AKT1;IKBKB;IKBKG GO:0016032| viral reproduction MAPK3;PML;MAPK1;HDAC1;IKBKG GO:0070423| nucleotide-binding oligomerization domain containing signaling pathway IKBKG;IKBKB GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKG;IKBKB GO:0051403| stress-activated MAPK cascade MAPK3;IKBKB;MAPK1;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKB;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;IKBKB GO:0006351| transcription, DNA-dependent PML;JUN;MAPK3;IKBKG;HDAC1;CCND1;MAPK1 GO:0009615| response to virus IKBKB;IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKB;PML;AKT1;JUN;MAPK3;HDAC1;IKBKG GO:0045087| innate immune response IKBKG;IKBKB;PML GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;IKBKB GO:0006974| response to DNA damage stimulus MAPK1;CCND1;CDKN1A;IKBKG;AKT1;MAPK3 GO:0038095| IKBKB;MAPK3;JUN;MAPK1;IKBKG GO:0006915| apoptotic process PML;AKT1;MAPK3;IKBKG;MAPK1 GO:0000187| activation of MAPK activity MAPK3;MAPK1;IKBKG GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKG;IKBKB GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKB;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;IKBKB;AKT1 13395:[DB04998 DB04878] DB04998|AGRO100 IKBKG DB04878|Voglibose MGAM common genes common pathways 13396:[DB04998 DB00831] DB04998|AGRO100 IKBKG DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;S100A4 GO:0038095| IKBKG;CALM1 GO:0006915| apoptotic process IKBKG;ADRA1A 13397:[DB04998 DB00311] DB04998|AGRO100 IKBKG DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways 13398:[DB04998 DB00308] DB04998|AGRO100 IKBKG DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways 13399:[DB04998 DB09225] DB04998|AGRO100 IKBKG DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG 13400:[DB04998 DB09237] DB04998|AGRO100 IKBKG DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways 13401:[DB04998 DB06762] DB04998|AGRO100 IKBKG DB06762|Pinacidil CYP3A4 common genes common pathways 13402:[DB04998 DB00570] DB04998|AGRO100 IKBKG DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0038095| IKBKG;JUN GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;JUN GO:0006351| transcription, DNA-dependent IKBKG;JUN GO:0006355| regulation of transcription, DNA-dependent IKBKG;JUN 13403:[DB04998 DB04348] DB04998|AGRO100 IKBKG DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;IKBKG GO:0045087| innate immune response NR1H4;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR1H4 GO:0016032| viral reproduction IKBKG;SLC10A1 GO:0006954| inflammatory response IKBKG;NR1H4 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1H4 13404:[DB04998 DB00463] DB04998|AGRO100 IKBKG DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:1901215| GABRB2;IKBKG;GABRB3 GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13405:[DB04998 DB00579] DB04998|AGRO100 IKBKG DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways 13406:[DB04998 DB04895] DB04998|AGRO100 IKBKG DB04895|Pegaptanib NRP1 common genes common pathways 13407:[DB04998 DB00678] DB04998|AGRO100 IKBKG DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes common pathways 13408:[DB04998 DB06695] DB04998|AGRO100 IKBKG DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways 13409:[DB04998 DB14538] DB04998|AGRO100 IKBKG DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0045087| innate immune response ANXA1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006955| immune response IKBKG;CYP11B1 GO:0006954| inflammatory response IKBKG;ANXA1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 13410:[DB04998 DB06283] DB04998|AGRO100 IKBKG DB06283|Ziconotide CYP3A4 common genes common pathways 13411:[DB04998 DB08819] DB04998|AGRO100 IKBKG DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG 13412:[DB04998 DB01384] DB04998|AGRO100 IKBKG DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG 13413:[DB04998 DB06712] DB04998|AGRO100 IKBKG DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways 13414:[DB04998 DB00627] DB04998|AGRO100 IKBKG DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0006915| apoptotic process HCAR2;SLC5A8;IKBKG 13415:[DB04998 DB00050] DB04998|AGRO100 IKBKG DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways 13416:[DB04998 DB00401] DB04998|AGRO100 IKBKG DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways 13417:[DB04998 DB01054] DB04998|AGRO100 IKBKG DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways 13418:[DB04998 DB05983] DB04998|AGRO100 IKBKG DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;NFKBIA GO:0016579| protein deubiquitination NFKBIA;IKBKG GO:0006915| apoptotic process NFKBIA;IKBKG GO:0038095| IKBKG;NFKBIA GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NFKBIA GO:0002223| stimulatory C-type lectin receptor signaling pathway NFKBIA;IKBKG GO:0016032| viral reproduction NFKBIA;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKBIA;IKBKG GO:0050852| T cell receptor signaling pathway NFKBIA;IKBKG 13419:[DB04998 DB09336] DB04998|AGRO100 IKBKG DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EPCAM;IKBKG 13420:[DB04998 DB04100] DB04998|AGRO100 IKBKG DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways 13421:[DB04998 DB00126] DB04998|AGRO100 IKBKG DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent KDM5D;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;KDM5D GO:0006974| response to DNA damage stimulus IKBKG;EGLN3;ALKBH2;ALKBH3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;EGLN1 GO:0006915| apoptotic process EGLN3;IKBKG 13422:[DB04998 DB01274] DB04998|AGRO100 IKBKG DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13423:[DB04998 DB09413] DB04998|AGRO100 IKBKG DB09413|Monopotassium phosphate ALPI common genes common pathways 13424:[DB04998 DB06360] DB04998|AGRO100 IKBKG DB06360|Lucatumumab CD40 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;CD40 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;CD40 GO:0006955| immune response CD40;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;CD40 GO:0006954| inflammatory response IKBKG;CD40 13425:[DB04998 DB00035] DB04998|AGRO100 IKBKG DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;IKBKG 13426:[DB04998 DB02745] DB04998|AGRO100 IKBKG DB02745|Uridine LSM6;SLC29A1 common genes common pathways 13427:[DB04998 DB00669] DB04998|AGRO100 IKBKG DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways 13428:[DB04998 DB09217] DB04998|AGRO100 IKBKG DB09217|Firocoxib PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG 13429:[DB04998 DB01151] DB04998|AGRO100 IKBKG DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process ADRA1A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;ADRB2 GO:0009615| response to virus IKBKG;CHRM2 GO:0006954| inflammatory response HRH1;ORM1;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG 13430:[DB04998 DB03506] DB04998|AGRO100 IKBKG DB03506|9-Deazaadenine APRT common genes common pathways 13431:[DB04998 DB12119] DB04998|AGRO100 IKBKG DB12119|Gevokizumab IL1B common genes common pathways GO:0000187| activation of MAPK activity IL1B;IKBKG GO:0006915| apoptotic process IKBKG;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;IL1B GO:0006954| inflammatory response IKBKG;IL1B GO:0006955| immune response IL1B;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IKBKG 13432:[DB04998 DB06636] DB04998|AGRO100 IKBKG DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways 13433:[DB04998 DB00081] DB04998|AGRO100 IKBKG DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FCGR2B;IKBKG GO:0006955| immune response FCGR3A;FCGR2C;C1QC;C1R;FCGR2B;FCGR3B;IKBKG;FCGR1A GO:0006954| inflammatory response IKBKG;FCGR2B GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response C1QC;C1QA;C1QB;C1R;IKBKG;FCGR1A 13434:[DB04998 DB08049] DB04998|AGRO100 IKBKG DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways 13435:[DB04998 DB11198] DB04998|AGRO100 IKBKG DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways 13436:[DB04998 DB00490] DB04998|AGRO100 IKBKG DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 13437:[DB04998 DB12474] DB04998|AGRO100 IKBKG DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways 13438:[DB04998 DB01043] DB04998|AGRO100 IKBKG DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;GRIN1 13439:[DB04998 DB09194] DB04998|AGRO100 IKBKG DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 GO:0009615| response to virus IKBKG;CHRM2 GO:0016032| viral reproduction HTR2A;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0006915| apoptotic process ADRA1A;IKBKG 13440:[DB04998 DB00968] DB04998|AGRO100 IKBKG DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways 13441:[DB04998 DB00910] DB04998|AGRO100 IKBKG DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;VDR GO:0006355| regulation of transcription, DNA-dependent VDR;IKBKG 13442:[DB04998 DB01107] DB04998|AGRO100 IKBKG DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:1901215| GABRB2;IKBKG;GABRB3 13443:[DB04998 DB01076] DB04998|AGRO100 IKBKG DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0006915| apoptotic process AHR;IKBKG GO:0006355| regulation of transcription, DNA-dependent AHR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;AHR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;IKBKG 13444:[DB04998 DB09073] DB04998|AGRO100 IKBKG DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0009615| response to virus IKBKG;CDK6 13445:[DB04998 DB08816] DB04998|AGRO100 IKBKG DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways 13446:[DB04998 DB00424] DB04998|AGRO100 IKBKG DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13447:[DB04998 DB09045] DB04998|AGRO100 IKBKG DB09045|Dulaglutide GLP1R common genes common pathways 13448:[DB04998 DB00706] DB04998|AGRO100 IKBKG DB00706|Tamsulosin ADRA1A;ADRA1D;ADRA1B;CYP3A4;CYP2D6;ORM1 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 GO:0006915| apoptotic process IKBKG;ADRA1A 13449:[DB04998 DB06307] DB04998|AGRO100 IKBKG DB06307|Apoptone BCL2 common genes common pathways GO:0006974| response to DNA damage stimulus BCL2;IKBKG GO:0006915| apoptotic process IKBKG;BCL2 13450:[DB04998 DB01418] DB04998|AGRO100 IKBKG DB01418|Acenocoumarol VKORC1;CYP2C9;CYP1A2;CYP2C19;CYP3A4;ALB;ORM1 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 13451:[DB04998 DB09299] DB04998|AGRO100 IKBKG DB09299|Tenofovir alafenamide pol;ABCB1 common genes common pathways 13452:[DB04998 DB12130] DB04998|AGRO100 IKBKG DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity ALK;IKBKG GO:0000187| activation of MAPK activity ALK;IKBKG 13453:[DB04998 DB00356] DB04998|AGRO100 IKBKG DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13454:[DB04998 DB09039] DB04998|AGRO100 IKBKG DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways 13455:[DB04998 DB04620] DB04998|AGRO100 IKBKG DB04620|Cycloleucine GRIN1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 13456:[DB04998 DB01332] DB04998|AGRO100 IKBKG DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways 13457:[DB04998 DB06016] DB04998|AGRO100 IKBKG DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;IKBKG;DRD2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0006954| inflammatory response IKBKG;HRH1 GO:0016032| viral reproduction IKBKG;HTR2A 13458:[DB04998 DB09289] DB04998|AGRO100 IKBKG DB09289|Tianeptine GRIA1;OPRM1;HTR1A;DRD3;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;IKBKG 13459:[DB04998 DB00322] DB04998|AGRO100 IKBKG DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways 13460:[DB04998 DB03664] DB04998|AGRO100 IKBKG DB03664|UP5 CMPK1 common genes common pathways 13461:[DB04998 DB01216] DB04998|AGRO100 IKBKG DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways 13462:[DB04998 DB06730] DB04998|AGRO100 IKBKG DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PGR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR 13463:[DB04998 DB00191] DB04998|AGRO100 IKBKG DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways 13464:[DB04998 DB06650] DB04998|AGRO100 IKBKG DB06650|Ofatumumab MS4A1 common genes common pathways 13465:[DB04998 DB00371] DB04998|AGRO100 IKBKG DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 13466:[DB04998 DB06684] DB04998|AGRO100 IKBKG DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways 13467:[DB04998 DB00530] DB04998|AGRO100 IKBKG DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG;EGFR GO:0009615| response to virus IKBKG;CYP1A1 GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 GO:0006954| inflammatory response ORM1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG 13468:[DB04998 DB00903] DB04998|AGRO100 IKBKG DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent LEF1;IKBKG GO:0006351| transcription, DNA-dependent LEF1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter LEF1;IKBKG 13469:[DB04998 DB07789] DB04998|AGRO100 IKBKG DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways 13470:[DB04998 DB01089] DB04998|AGRO100 IKBKG DB01089|Deserpidine SLC18A2 common genes common pathways 13471:[DB04998 DB13166] DB04998|AGRO100 IKBKG DB13166|Zofenopril ACE common genes common pathways 13472:[DB04998 DB01223] DB04998|AGRO100 IKBKG DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;IKBKG GO:0006351| transcription, DNA-dependent HDAC2;IKBKG GO:0006954| inflammatory response ADORA3;ADORA1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;HDAC2 13473:[DB04998 DB00108] DB04998|AGRO100 IKBKG DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;ICAM1 GO:0006954| inflammatory response FCGR2B;IKBKG GO:0016032| viral reproduction IKBKG;ICAM1;FCGR2B GO:0006955| immune response C1QC;FCGR3A;FCGR2C;FCGR1A;IKBKG;FCGR2B;FCGR3B;C1R GO:0045087| innate immune response C1QA;C1QC;FCGR1A;IKBKG;C1QB;C1R GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG 13474:[DB04998 DB09236] DB04998|AGRO100 IKBKG DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 GO:0050852| T cell receptor signaling pathway CACNB3;IKBKG 13475:[DB04998 DB08930] DB04998|AGRO100 IKBKG DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes common pathways 13476:[DB04998 DB09070] DB04998|AGRO100 IKBKG DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR1 13477:[DB04998 DB04905] DB04998|AGRO100 IKBKG DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 GO:0006954| inflammatory response HRH1;IKBKG 13478:[DB04998 DB00487] DB04998|AGRO100 IKBKG DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 13479:[DB04998 DB00682] DB04998|AGRO100 IKBKG DB00682|Warfarin VKORC1;NR1I2;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2C8;CYP2C18;CYP1A1;ALB;ORM1 common genes common pathways GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0006954| inflammatory response ORM1;IKBKG 13480:[DB04998 DB05920] DB04998|AGRO100 IKBKG DB05920|RTA 744 TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 13481:[DB04998 DB11397] DB04998|AGRO100 IKBKG DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways 13482:[DB04998 DB01589] DB04998|AGRO100 IKBKG DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 13483:[DB04998 DB00104] DB04998|AGRO100 IKBKG DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways 13484:[DB04998 DB01064] DB04998|AGRO100 IKBKG DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0000187| activation of MAPK activity SOD1;IKBKG;MAPK1 GO:0006915| apoptotic process MAPK1;IKBKG GO:0038095| PIK3R2;MAPK1;IKBKG;PIK3R1 GO:0006974| response to DNA damage stimulus MAPK1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PIK3R2;PIK3R1;IKBKG;ADRB2 GO:0009615| response to virus CYP1A1;IKBKG GO:0051403| stress-activated MAPK cascade IKBKG;MAPK1 GO:0006351| transcription, DNA-dependent IKBKG;MAPK1 GO:0016032| viral reproduction MAPK1;PIK3R1;IKBKG GO:0050852| T cell receptor signaling pathway PIK3R1;IKBKG;MAPK1;PIK3R2 GO:0006355| regulation of transcription, DNA-dependent IKBKG;MAPK1 13485:[DB04998 DB06414] DB04998|AGRO100 IKBKG DB06414|Etravirine CYP3A4;CYP2C9;CYP2C19;ABCB1;ABCB4 common genes common pathways 13486:[DB04998 DB09280] DB04998|AGRO100 IKBKG DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways GO:0016579| protein deubiquitination CFTR;IKBKG 13487:[DB04998 DB00633] DB04998|AGRO100 IKBKG DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13488:[DB04998 DB01349] DB04998|AGRO100 IKBKG DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways GO:0006954| inflammatory response IKBKG;AGTR2 13489:[DB04998 DB00471] DB04998|AGRO100 IKBKG DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;ALOX5 13490:[DB04998 DB01587] DB04998|AGRO100 IKBKG DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0006915| apoptotic process TSPO;IKBKG 13491:[DB04998 DB13500] DB04998|AGRO100 IKBKG DB13500|Otilonium CYP3A4 common genes common pathways 13492:[DB04998 DB09154] DB04998|AGRO100 IKBKG DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 13493:[DB04998 DB01231] DB04998|AGRO100 IKBKG DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 13494:[DB04998 DB00710] DB04998|AGRO100 IKBKG DB00710|Ibandronate FDPS common genes common pathways GO:0016032| viral reproduction IKBKG;FDPS 13495:[DB04998 DB00917] DB04998|AGRO100 IKBKG DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0007254| JNK cascade IKBKG;PTGER4 GO:0006955| immune response PTGDR2;PTGER4;IKBKG 13496:[DB04998 DB01583] DB04998|AGRO100 IKBKG DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;IKBKG;THRB GO:0006351| transcription, DNA-dependent THRB;IKBKG;THRA GO:0016032| viral reproduction IKBKG;SLC10A1 GO:0006355| regulation of transcription, DNA-dependent THRA;IKBKG;THRB 13497:[DB04998 DB00331] DB04998|AGRO100 IKBKG DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways 13498:[DB04998 DB07700] DB04998|AGRO100 IKBKG DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways 13499:[DB04998 DB04951] DB04998|AGRO100 IKBKG DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways 13500:[DB04998 DB09230] DB04998|AGRO100 IKBKG DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways 13501:[DB04998 DB01264] DB04998|AGRO100 IKBKG DB01264|Darunavir pol;CYP3A4;SLCO1B1;ABCB1 common genes common pathways 13502:[DB04998 DB00850] DB04998|AGRO100 IKBKG DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0038095| IKBKG;CALM1 13503:[DB04998 DB04957] DB04998|AGRO100 IKBKG DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 13504:[DB04998 DB05679] DB04998|AGRO100 IKBKG DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways GO:0045087| innate immune response IL23A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;IL23A GO:0006955| immune response IL23A;IKBKG GO:0006954| inflammatory response IL23A;IKBKG 13505:[DB04998 DB06479] DB04998|AGRO100 IKBKG DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways 13506:[DB04998 DB01456] DB04998|AGRO100 IKBKG DB01456|5-androstenedione CYP3A4 common genes common pathways 13507:[DB04998 DB01399] DB04998|AGRO100 IKBKG DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13508:[DB04998 DB05514] DB04998|AGRO100 IKBKG DB05514|Cobiprostone CLCN2 common genes common pathways 13509:[DB04998 DB01559] DB04998|AGRO100 IKBKG DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 13510:[DB04998 DB09091] DB04998|AGRO100 IKBKG DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;HDAC2;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;HDAC2;IKBKG GO:0006355| regulation of transcription, DNA-dependent HDAC2;NR3C1;IKBKG GO:0006915| apoptotic process NR3C1;IKBKG 13511:[DB04998 DB04794] DB04998|AGRO100 IKBKG DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways 13512:[DB04998 DB12141] DB04998|AGRO100 IKBKG DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0045087| innate immune response AXL;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;ALK GO:0006954| inflammatory response AXL;IKBKG GO:0016032| viral reproduction IKBKG;AXL;HTR2A GO:0000187| activation of MAPK activity IKBKG;ALK 13513:[DB04998 DB00769] DB04998|AGRO100 IKBKG DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0006915| apoptotic process NR3C1;IKBKG 13514:[DB04998 DB00252] DB04998|AGRO100 IKBKG DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes common pathways GO:0006955| immune response CYP11B1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG 13515:[DB04998 DB00078] DB04998|AGRO100 IKBKG DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response C1S;C1QC;C1QA;C1QB;C1R;IKBKG;FCGR1A GO:0006955| immune response FCGR2B;FCGR3B;C1R;FCGR1A;IKBKG;C1QC;FCGR3A;FCGR2C GO:0016032| viral reproduction FCGR2B;IKBKG GO:0006954| inflammatory response IKBKG;FCGR2B 13516:[DB04998 DB09140] DB04998|AGRO100 IKBKG DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0006954| inflammatory response IKBKG;NOX1 13517:[DB04998 DB04946] DB04998|AGRO100 IKBKG DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0006954| inflammatory response HRH1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3 GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity DRD4;IKBKG 13518:[DB04998 DB11614] DB04998|AGRO100 IKBKG DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0006955| immune response PTAFR;IKBKG GO:0006954| inflammatory response PTAFR;IKBKG;HRH1 13519:[DB04998 DB14064] DB04998|AGRO100 IKBKG DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways 13520:[DB04998 DB06814] DB04998|AGRO100 IKBKG DB06814|Protokylol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination ADRB2;IKBKG 13521:[DB04998 DB09064] DB04998|AGRO100 IKBKG DB09064|Ciprofibrate PPARA common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARA;IKBKG GO:1901215| IKBKG;PPARA GO:0006351| transcription, DNA-dependent PPARA;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;IKBKG 13522:[DB04998 DB06145] DB04998|AGRO100 IKBKG DB06145|Spiramycin rplC;CYP3A4 common genes common pathways 13523:[DB04998 DB00773] DB04998|AGRO100 IKBKG DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 GO:0006974| response to DNA damage stimulus IKBKG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 13524:[DB04998 DB00580] DB04998|AGRO100 IKBKG DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG 13525:[DB04998 DB00515] DB04998|AGRO100 IKBKG DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2 GO:0006974| response to DNA damage stimulus MPG;IKBKG GO:0000187| activation of MAPK activity IKBKG;SOD1 13526:[DB04998 DB00794] DB04998|AGRO100 IKBKG DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13527:[DB04998 DB00178] DB04998|AGRO100 IKBKG DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0006954| inflammatory response BDKRB1;IKBKG 13528:[DB04998 DB00592] DB04998|AGRO100 IKBKG DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:1901215| IKBKG;GABRB3 13529:[DB04998 DB09227] DB04998|AGRO100 IKBKG DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways 13530:[DB04998 DB00925] DB04998|AGRO100 IKBKG DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0038095| CALM1;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0016579| protein deubiquitination ADRB2;IKBKG 13531:[DB04998 DB12418] DB04998|AGRO100 IKBKG DB12418|Saccharin CA3 common genes common pathways 13532:[DB04998 DB00449] DB04998|AGRO100 IKBKG DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13533:[DB04998 DB12061] DB04998|AGRO100 IKBKG DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 GO:0000187| activation of MAPK activity IKBKG;DRD4 13534:[DB04998 DB06215] DB04998|AGRO100 IKBKG DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0006955| immune response IKBKG;FTH1 13535:[DB04998 DB09167] DB04998|AGRO100 IKBKG DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006954| inflammatory response HRH1;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0009615| response to virus CHRM2;IKBKG 13536:[DB04998 DB00446] DB04998|AGRO100 IKBKG DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways GO:0045087| innate immune response IKBKG;CD55 GO:0016032| viral reproduction CD55;IKBKG 13537:[DB04998 DB01973] DB04998|AGRO100 IKBKG DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 13538:[DB04998 DB00373] DB04998|AGRO100 IKBKG DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13539:[DB04998 DB09462] DB04998|AGRO100 IKBKG DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0006954| inflammatory response PLA2G2E;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARD;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PPARD GO:0006915| apoptotic process TGFBR2;PPARD;PAEP;ITPR1;IKBKG 13540:[DB04998 DB02508] DB04998|AGRO100 IKBKG DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0016032| viral reproduction IKBKG;FDPS 13541:[DB04998 DB00319] DB04998|AGRO100 IKBKG DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways 13542:[DB04998 DB00393] DB04998|AGRO100 IKBKG DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0006915| apoptotic process AHR;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;CACNB3 GO:0006355| regulation of transcription, DNA-dependent AHR;NR3C2;IKBKG GO:0006351| transcription, DNA-dependent AHR;IKBKG;NR3C2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;IKBKG 13543:[DB04998 DB00716] DB04998|AGRO100 IKBKG DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0000187| activation of MAPK activity FPR1;IKBKG GO:0006954| inflammatory response PTGDR;FPR1;IKBKG GO:0006955| immune response CYSLTR2;IKBKG 13544:[DB04998 DB00825] DB04998|AGRO100 IKBKG DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0006955| immune response OPRK1;IKBKG GO:0050852| T cell receptor signaling pathway CACNB3;IKBKG 13545:[DB04998 DB01105] DB04998|AGRO100 IKBKG DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways 13546:[DB04998 DB00030] DB04998|AGRO100 IKBKG DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0006915| apoptotic process IKBKG;RB1 GO:0000187| activation of MAPK activity INSR;IKBKG GO:0006355| regulation of transcription, DNA-dependent RB1;IKBKG;INSR GO:0006955| immune response IGF1R;IKBKG GO:0016032| viral reproduction IKBKG;IDE;RB1 GO:0006351| transcription, DNA-dependent IKBKG;RB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RB1;IKBKG 13547:[DB04998 DB00207] DB04998|AGRO100 IKBKG DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways GO:0045087| innate immune response IKBKG;PADI4 GO:0006351| transcription, DNA-dependent PADI4;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;PADI4 13548:[DB04998 DB01128] DB04998|AGRO100 IKBKG DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways GO:0016579| protein deubiquitination IKBKG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent IKBKG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;IKBKG GO:0006351| transcription, DNA-dependent AR;IKBKG 13549:[DB04998 DB06290] DB04998|AGRO100 IKBKG DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes common pathways GO:0016032| viral reproduction SLC10A1;IKBKG 13550:[DB04998 DB06287] DB04998|AGRO100 IKBKG DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0043276| anoikis IKBKG;MTOR 13551:[DB04998 DB13884] DB04998|AGRO100 IKBKG DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways 13552:[DB04998 DB11995] DB04998|AGRO100 IKBKG DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways 13553:[DB04998 DB06457] DB04998|AGRO100 IKBKG DB06457|Tecastemizole KCNH2 common genes common pathways 13554:[DB04998 DB07117] DB04998|AGRO100 IKBKG DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 13555:[DB04998 DB00829] DB04998|AGRO100 IKBKG DB00829|Diazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9;CYP2B6;CYP2C18;CYP2C8;PTGS1;CYP2E1;ALB;ABCB1 common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 GO:0006954| inflammatory response PTGS1;IKBKG GO:0006915| apoptotic process TSPO;IKBKG 13556:[DB04998 DB00864] DB04998|AGRO100 IKBKG DB00864|Tacrolimus FKBP1A;CYP3A7;CYP3A5;CYP3A4;ALB;ORM1;ABCB1;ABCA5;SLCO1B1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;IKBKG GO:0006954| inflammatory response ORM1;IKBKG 13557:[DB04998 DB00734] DB04998|AGRO100 IKBKG DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B;DRD4 GO:0006915| apoptotic process IKBKG;ADRA1A GO:0006954| inflammatory response HRH1;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG 13558:[DB04998 DB08794] DB04998|AGRO100 IKBKG DB08794|Ethyl biscoumacetate GLUL;CYP3A4 common genes common pathways 13559:[DB04998 DB05750] DB04998|AGRO100 IKBKG DB05750|AVE-1625 CNR1 common genes common pathways 13560:[DB04998 DB00465] DB04998|AGRO100 IKBKG DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 13561:[DB04998 DB00653] DB04998|AGRO100 IKBKG DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways 13562:[DB04998 DB01147] DB04998|AGRO100 IKBKG DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 13563:[DB04998 DB00573] DB04998|AGRO100 IKBKG DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0045087| innate immune response IKBKG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IKBKG;PPARA GO:0006351| transcription, DNA-dependent PPARA;IKBKG;PPARG GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG;IKBKG 13564:[DB04998 DB00120] DB04998|AGRO100 IKBKG DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways 13565:[DB04998 DB09329] DB04998|AGRO100 IKBKG DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways 13566:[DB04998 DB00788] DB04998|AGRO100 IKBKG DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13567:[DB04998 DB01267] DB04998|AGRO100 IKBKG DB01267|Paliperidone HTR2A;DRD2;HRH1;ADRA1A;ADRA1B;DRD4;HTR1D;DRD3;HTR2C;ADRA2A;ADRA2B;ADRA2C;HTR1A;DRD1;HTR7;CYP3A4;CYP2D6;CYP3A5;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0006954| inflammatory response HRH1;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG 13568:[DB04998 DB00224] DB04998|AGRO100 IKBKG DB00224|Indinavir pol;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;ABCB1;SLC22A1;ABCC1;SLCO1A2;SLCO1B1;ABCC2;SLCO2B1;ABCB11 common genes common pathways 13569:[DB04998 DB00869] DB04998|AGRO100 IKBKG DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways 13570:[DB04998 DB11636] DB04998|AGRO100 IKBKG DB11636|Nomegestrol CYP3A4 common genes common pathways 13571:[DB04998 DB00998] DB04998|AGRO100 IKBKG DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways 13572:[DB04998 DB13749] DB04998|AGRO100 IKBKG DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;ABL1 GO:0045087| innate immune response ABL1;IKBKG GO:0006915| apoptotic process IKBKG;ABL1 13573:[DB04998 DB12089] DB04998|AGRO100 IKBKG DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways 13574:[DB04998 DB07173] DB04998|AGRO100 IKBKG DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 13575:[DB04998 DB00539] DB04998|AGRO100 IKBKG DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG GO:0006351| transcription, DNA-dependent ESR1;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG GO:0016579| protein deubiquitination IKBKG;ESR1 13576:[DB04998 DB09061] DB04998|AGRO100 IKBKG DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0045087| innate immune response IKBKG;PPARG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IKBKG;PPARG GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;ADORA1;IDO1;ALOX15;IKBKG;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;PLA2G1B;CAT GO:0006955| immune response CNR2;OPRD1;IKBKG GO:0016032| viral reproduction IKBKG;VDAC1;HTR2A GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG GO:0006915| apoptotic process GPX1;VDAC1;IKBKG GO:0000187| activation of MAPK activity IKBKG;PLA2G1B;CHRNA7;SOD1 13577:[DB04998 DB01873] DB04998|AGRO100 IKBKG DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 13578:[DB04998 DB11135] DB04998|AGRO100 IKBKG DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways 13579:[DB04998 DB00950] DB04998|AGRO100 IKBKG DB00950|Fexofenadine HRH1;ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3;SLC22A8 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 13580:[DB04998 DB00397] DB04998|AGRO100 IKBKG DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 13581:[DB04998 DB00908] DB04998|AGRO100 IKBKG DB00908|Quinidine SCN5A;KCNK1;KCNK6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A7;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP2B6;CYP2C9;CYP2C8;ORM1;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A8;ABCC2;SLC22A4;SLCO1B1;ABCB11 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0006954| inflammatory response IKBKG;ORM1 13582:[DB04998 DB05012] DB04998|AGRO100 IKBKG DB05012|XEN2174 SLC6A2 common genes common pathways 13583:[DB04998 DB00728] DB04998|AGRO100 IKBKG DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 13584:[DB04998 DB09047] DB04998|AGRO100 IKBKG DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 13585:[DB04998 DB00643] DB04998|AGRO100 IKBKG DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13586:[DB04998 DB00612] DB04998|AGRO100 IKBKG DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 13587:[DB04998 DB00213] DB04998|AGRO100 IKBKG DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways 13588:[DB04998 DB08922] DB04998|AGRO100 IKBKG DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0006954| inflammatory response HRH1;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 GO:0009615| response to virus IKBKG;CYP1A1 GO:0000187| activation of MAPK activity DRD4;IKBKG GO:0006915| apoptotic process ADRA1A;IKBKG 13589:[DB04998 DB01576] DB04998|AGRO100 IKBKG DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 13590:[DB04998 DB01068] DB04998|AGRO100 IKBKG DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:1901215| GABRB2;IKBKG;GABRB3 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0006915| apoptotic process TSPO;IKBKG 13591:[DB04998 DB03615] DB04998|AGRO100 IKBKG DB03615|Ribostamycin P4HB;rpsL common genes common pathways 13592:[DB04998 DB00647] DB04998|AGRO100 IKBKG DB00647|Dextropropoxyphene OPRM1;OPRD1;OPRK1;CES1;CYP3A4;CYP2D6;CYP2C8 common genes common pathways GO:0006955| immune response OPRD1;IKBKG;OPRK1 13593:[DB04998 DB11598] DB04998|AGRO100 IKBKG DB11598|Antithrombin III human SERPINC1 common genes common pathways 13594:[DB04998 DB02236] DB04998|AGRO100 IKBKG DB02236|Glycinamide Ribonucleotide GART common genes common pathways 13595:[DB04998 DB00270] DB04998|AGRO100 IKBKG DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways 13596:[DB04998 DB00606] DB04998|AGRO100 IKBKG DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways 13597:[DB04998 DB08971] DB04998|AGRO100 IKBKG DB08971|Fluocortolone CYP3A4 common genes common pathways 13598:[DB04998 DB00999] DB04998|AGRO100 IKBKG DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways 13599:[DB04998 DB13488] DB04998|AGRO100 IKBKG DB13488|Bencyclane CYP3A4 common genes common pathways 13600:[DB04998 DB00741] DB04998|AGRO100 IKBKG DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0045087| innate immune response IKBKG;ANXA1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006954| inflammatory response IKBKG;ANXA1 GO:0006955| immune response IKBKG;CYP11B1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 13601:[DB04998 DB08872] DB04998|AGRO100 IKBKG DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways GO:0006915| apoptotic process IKBKG;SLC5A8 13602:[DB04998 DB06421] DB04998|AGRO100 IKBKG DB06421|Declopramide TOP2A;TOP2B common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG 13603:[DB04998 DB00233] DB04998|AGRO100 IKBKG DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;CHUK GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKG;CHUK GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;CHUK GO:0038095| IKBKG;CHUK GO:0009615| response to virus CHUK;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;IKBKG GO:0045087| innate immune response CHUK;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;CHUK GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKG;CHUK GO:0051403| stress-activated MAPK cascade CHUK;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;CHUK GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;CHUK GO:0051092| positive regulation of NF-kappaB transcription factor activity CHUK;IKBKG GO:0006954| inflammatory response PTGS2;ALOX5;CHUK;PLA2G2E;IKBKG GO:0006955| immune response CHUK;IKBKG GO:0070423| nucleotide-binding oligomerization domain containing signaling pathway IKBKG;CHUK GO:0050852| T cell receptor signaling pathway IKBKG;CHUK 13604:[DB04998 DB11606] DB04998|AGRO100 IKBKG DB11606|Susoctocog alfa VWF common genes common pathways 13605:[DB04998 DB05155] DB04998|AGRO100 IKBKG DB05155|CR665 OPRK1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1 13606:[DB04998 DB09080] DB04998|AGRO100 IKBKG DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13607:[DB04998 DB00561] DB04998|AGRO100 IKBKG DB00561|Doxapram KCNK3;KCNK9 common genes common pathways 13608:[DB04998 DB11455] DB04998|AGRO100 IKBKG DB11455|Robenacoxib PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG 13609:[DB04998 DB01357] DB04998|AGRO100 IKBKG DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG GO:0006351| transcription, DNA-dependent ESR1;IKBKG GO:0016579| protein deubiquitination IKBKG;ESR1 13610:[DB04998 DB06654] DB04998|AGRO100 IKBKG DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13611:[DB04998 DB00613] DB04998|AGRO100 IKBKG DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 13612:[DB04998 DB01612] DB04998|AGRO100 IKBKG DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways 13613:[DB04998 DB09220] DB04998|AGRO100 IKBKG DB09220|Nicorandil ABCC9 common genes common pathways 13614:[DB04998 DB14518] DB04998|AGRO100 IKBKG DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:1901215| IKBKG;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;APP GO:0045087| innate immune response APP;IKBKG GO:0006915| apoptotic process IKBKG;APP GO:0000187| activation of MAPK activity APP;IKBKG 13615:[DB04998 DB00220] DB04998|AGRO100 IKBKG DB00220|Nelfinavir CYP2B6;CYP2C19;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;CYP2C9;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways 13616:[DB04998 DB00867] DB04998|AGRO100 IKBKG DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 13617:[DB04998 DB00169] DB04998|AGRO100 IKBKG DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;VDR GO:0006355| regulation of transcription, DNA-dependent IKBKG;VDR 13618:[DB04998 DB11901] DB04998|AGRO100 IKBKG DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AR GO:0006351| transcription, DNA-dependent IKBKG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent IKBKG;AR GO:1901215| GABRB3;IKBKG;GABRB2 GO:0016579| protein deubiquitination IKBKG;AR 13619:[DB04998 DB01586] DB04998|AGRO100 IKBKG DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0006351| transcription, DNA-dependent NR1H4;IKBKG GO:0045087| innate immune response IKBKG;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1H4 GO:0006355| regulation of transcription, DNA-dependent NR1H4;IKBKG GO:0006954| inflammatory response IKBKG;NR1H4 GO:0016032| viral reproduction IKBKG;SLC10A1 13620:[DB04998 DB00880] DB04998|AGRO100 IKBKG DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways 13621:[DB04998 DB05495] DB04998|AGRO100 IKBKG DB05495|PG-530742 MMP9 common genes common pathways 13622:[DB04998 DB11633] DB04998|AGRO100 IKBKG DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways 13623:[DB04998 DB01229] DB04998|AGRO100 IKBKG DB01229|Paclitaxel TUBB1;BCL2;NR1I2;MAP4;MAP2;MAPT;CYP3A5;CYP3A7;CYP2C8;CYP3A4;CYP19A1;CYP1B1;ABCB11;ABCB1;ABCC1;ABCC10;SLCO1B3;ABCG2;ABCC2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;BCL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006915| apoptotic process BCL2;IKBKG 13624:[DB04998 DB12267] DB04998|AGRO100 IKBKG DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0000187| activation of MAPK activity ALK;IKBKG;INSR GO:0006915| apoptotic process ABL1;IKBKG;ERBB4 GO:0006355| regulation of transcription, DNA-dependent ERBB2;ERBB4;IKBKG;ABL1;INSR GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;ALK GO:0006955| immune response IGF1R;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ABL1 GO:0006351| transcription, DNA-dependent IKBKG;ERBB2;ERBB4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;EGFR;MET GO:0045087| innate immune response IKBKG;ABL1 GO:0006974| response to DNA damage stimulus ABL1;IKBKG 13625:[DB04998 DB03866] DB04998|AGRO100 IKBKG DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG 13626:[DB04998 DB04828] DB04998|AGRO100 IKBKG DB04828|Zomepirac PTGDR2;CYP3A4;ALB common genes common pathways GO:0006955| immune response IKBKG;PTGDR2 13627:[DB04998 DB09074] DB04998|AGRO100 IKBKG DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways GO:0006915| apoptotic process IKBKG;PARP1 GO:0006974| response to DNA damage stimulus IKBKG;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PARP1 GO:0006351| transcription, DNA-dependent PARP1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;PARP1 13628:[DB04998 DB00411] DB04998|AGRO100 IKBKG DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 13629:[DB04998 DB00918] DB04998|AGRO100 IKBKG DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes common pathways 13630:[DB04998 DB00957] DB04998|AGRO100 IKBKG DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0016579| protein deubiquitination AR;ESR1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR;ESR1;AR GO:0006351| transcription, DNA-dependent PGR;IKBKG;AR;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR;AR;ESR1 13631:[DB04998 DB04860] DB04998|AGRO100 IKBKG DB04860|Isatoribine TLR7 common genes common pathways GO:0045087| innate immune response TLR7;IKBKG GO:0006954| inflammatory response TLR7;IKBKG GO:0006955| immune response TLR7;IKBKG 13632:[DB04998 DB00841] DB04998|AGRO100 IKBKG DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2;ESR1 GO:0006351| transcription, DNA-dependent IKBKG;ESR1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR1 GO:0016579| protein deubiquitination ESR1;ADRB2;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 13633:[DB04998 DB05046] DB04998|AGRO100 IKBKG DB05046|V1003 OPRK1;OPRM1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1 13634:[DB04998 DB11817] DB04998|AGRO100 IKBKG DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0045087| innate immune response JAK3;JAK2;PTK2B;IKBKG;JAK1 GO:0006954| inflammatory response JAK3;IKBKG GO:0006915| apoptotic process IKBKG;PTK2B;JAK2 13635:[DB04998 DB01214] DB04998|AGRO100 IKBKG DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13636:[DB04998 DB08808] DB04998|AGRO100 IKBKG DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 13637:[DB04998 DB14059] DB04998|AGRO100 IKBKG DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0045087| innate immune response IKBKG;NFKB2;NFKB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB2;IKBKG;RELA;NFKB1 GO:0006351| transcription, DNA-dependent IKBKG;NFKB2;NFKB1;RELA GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;RELA GO:0002223| stimulatory C-type lectin receptor signaling pathway RELA;NFKB1;IKBKG GO:0051403| stress-activated MAPK cascade NFKB1;IKBKG GO:0016032| viral reproduction RELA;IKBKG GO:0006954| inflammatory response IKBKG;NFKB2;NFKB1;PTGS2;RELA GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;RELA;IKBKG;NFKB2 GO:0050852| T cell receptor signaling pathway RELA;NFKB1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NFKB2;NFKB1;RELA GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB2;IKBKG;NFKB1 GO:0006915| apoptotic process NFKB1;IKBKG GO:0038095| IKBKG;NFKB1;RELA 13638:[DB04998 DB01309] DB04998|AGRO100 IKBKG DB01309|Insulin Glulisine INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;INSR GO:0000187| activation of MAPK activity IKBKG;INSR 13639:[DB04998 DB00040] DB04998|AGRO100 IKBKG DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 13640:[DB04998 DB00309] DB04998|AGRO100 IKBKG DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways 13641:[DB04998 DB06736] DB04998|AGRO100 IKBKG DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13642:[DB04998 DB11988] DB04998|AGRO100 IKBKG DB11988|Ocrelizumab MS4A1 common genes common pathways 13643:[DB04998 DB00625] DB04998|AGRO100 IKBKG DB00625|Efavirenz pol;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP2C8;UGT1A1;ALB;ABCB11;SLC22A1 common genes common pathways 13644:[DB04998 DB09102] DB04998|AGRO100 IKBKG DB09102|Daclatasvir CYP3A5;CYP3A4;CYP3A43;CYP3A7;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways 13645:[DB04998 DB05018] DB04998|AGRO100 IKBKG DB05018|Migalastat GLA;UGT1A1 common genes common pathways 13646:[DB04998 DB00674] DB04998|AGRO100 IKBKG DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;CHRNA7 13647:[DB04998 DB03962] DB04998|AGRO100 IKBKG DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways 13648:[DB04998 DB06153] DB04998|AGRO100 IKBKG DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A GO:0006954| inflammatory response IKBKG;HRH1 GO:0016032| viral reproduction HTR2A;IKBKG GO:0009615| response to virus CHRM2;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B 13649:[DB04998 DB00695] DB04998|AGRO100 IKBKG DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways 13650:[DB04998 DB00911] DB04998|AGRO100 IKBKG DB00911|Tinidazole CYP3A4;ABCB11 common genes common pathways 13651:[DB04998 DB09129] DB04998|AGRO100 IKBKG DB09129|Chromic chloride INSR common genes common pathways GO:0000187| activation of MAPK activity IKBKG;INSR GO:0006355| regulation of transcription, DNA-dependent INSR;IKBKG 13652:[DB04998 DB06796] DB04998|AGRO100 IKBKG DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways 13653:[DB04998 DB06472] DB04998|AGRO100 IKBKG DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction ITGB3;IKBKG 13654:[DB04998 DB00384] DB04998|AGRO100 IKBKG DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways 13655:[DB04998 DB00906] DB04998|AGRO100 IKBKG DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes common pathways 13656:[DB04998 DB08811] DB04998|AGRO100 IKBKG DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways 13657:[DB04998 DB01092] DB04998|AGRO100 IKBKG DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 13658:[DB04998 DB01077] DB04998|AGRO100 IKBKG DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 13659:[DB04998 DB00942] DB04998|AGRO100 IKBKG DB00942|Cycrimine CHRM1 common genes common pathways 13660:[DB04998 DB08860] DB04998|AGRO100 IKBKG DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0016032| viral reproduction IKBKG;SLC10A1 13661:[DB04998 DB12010] DB04998|AGRO100 IKBKG DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade BTK;RIPK1;TBK1;IKBKB;IKBKG;RIPK2;ROCK2 GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKB;TBK1;RIPK1;IKBKE;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway SYK;IKBKG;IKBKB;RIPK1 GO:0016579| protein deubiquitination CDK1;RIPK1;TGFBR1;RIPK2;IKBKG GO:0038095| TEC;MAP3K1;ITK;BTK;IKBKB;MAPK9;MAPK10;IKBKG;PRKCQ;PDPK1;SYK;LYN;PAK1;FER;PAK2 GO:0000187| activation of MAPK activity PAK3;MAP3K2;ALK;CDK1;LRRK2;MAP2K5;TAOK2;MAP2K3;MAP3K11;MAPKAPK5;MAP2K2;KIT;MAPK14;NTRK3;RIPK2;TAOK1;IRAK1;SYK;INSR;MAPK10;IKBKG;PRKAA1;MAP2K6 GO:0006915| apoptotic process TAOK2;TGFBR1;DAPK3;RIPK1;FGFR2;DAPK2;BTK;CHEK1;STK26;ERBB4;TGFBR2;PAK6;DAPK1;PKN2;MAP3K9;PRKCE;CSNK2A1;RAF1;CDK1;PIM1;HIPK3;PAK4;PRKD1;ABL1;CHEK2;MELK;PIM3;IKBKG;PTK2B;STK17A;MAP3K10;MAP2K6;MKNK2;STK24;EPHA2;EPHA7;TAOK1;NUAK2;MAPK14;RPS6KA3;PAK1;PAK2;RIPK2;STK17B;SLK;CSNK2A2;RPS6KA1;FGFR3;STK3;PRKCD;PAK5;PLK3;HIPK2;JAK2;BMX;ERN1 GO:0007254| JNK cascade MAP3K11;MAP4K3;MAP3K13;MAPK9;MAP3K12;MAP3K10;MAPK10;IKBKG;MAP4K2;MINK1;IRAK4;RIPK2;IRAK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PRKD1;IKBKG;MAPK7;YES1;EGFR;BMPR2;TXK;CASK;RIPK2;MAPK14;RPS6KA3;RPS6KA1;HIPK2;BMPR1B;MAP2K5;TBK1;FGFR2;CAMK1;RIPK1;ACVR1B;IKBKB;RAF1;MET;STK16;ACVR1 GO:0009615| response to virus FGR;IRAK3;IKBKB;MST1R;TBK1;EIF2AK2;SRC;DCLK1;IKBKG GO:0045087| innate immune response FGR;JAK3;ABL2;IKBKB;FES;PTK6;TNK2;TNK1;AXL;BLK;MST1R;IKBKE;TYK2;TBK1;EIF2AK2;TEC;SRC;HCK;MATK;ITK;CSF1R;BTK;FER;ZAP70;RIPK2;PIK3CG;FYN;IRAK1;PTK2;SYK;LYN;JAK2;PIK3CD;IRAK4;BMX;YES1;RIOK3;ABL1;PTK2B;IKBKG;CSK;PRKD1;MAP4K2;FRK;JAK1;SRMS;LCK GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKB;IKBKG GO:0006974| response to DNA damage stimulus IKBKE;TAOK2;NUAK1;CHEK1;MAPK14;TAOK3;LYN;TAOK1;NEK4;HIPK2;TLK2;PLK3;IKBKG;ABL1;CHEK2;TLK1 GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKG;RIPK1;IKBKB GO:0051403| stress-activated MAPK cascade IKBKG;IKBKB;TAOK2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IRAK4;PLK2;IRAK1;FYN;RIPK2;MAP3K3;PRKD1;IKBKG;ABL1;IKBKB;PRKCE;TBK1;RIPK1;IKBKE GO:0002223| stimulatory C-type lectin receptor signaling pathway PRKCD;PRKACB;SYK;PDPK1;LYN;PAK1;FYN;PAK2;IKBKG;RAF1;PRKACA;IKBKB;PAK3;SRC GO:0006351| transcription, DNA-dependent HIPK2;ERN1;CSNK2A2;MAPK14;PRKAA2;PKN1;MAPK13;TXK;PDPK1;PRKAA1;MAP2K6;CHEK2;IKBKG;HIPK3;CSNK2A1;MAP3K9;PKN2;FGFR1;ERBB4;BTK;DAPK3;ERBB2;EIF2AK2 GO:0051092| positive regulation of NF-kappaB transcription factor activity ALK;MAP3K13;IRAK3;IKBKB;BTK;CAMK2A;PRKCI;EIF2AK2;RIPK1;IRAK4;IRAK1;NTRK1;RIPK2;FER;PRKCQ;PRKD1;RIPK4;IKBKG GO:0043276| anoikis DAPK2;MTOR;IKBKG GO:0006954| inflammatory response ALOX5;MAP2K3;CSF1R;KIT;HCK;BMPR1B;TBK1;AXL;IKBKB;JAK3;CAMK1D;PRKCQ;IKBKG;PRKD1;PIK3CD;RIPK2;PIK3CG;SYK;LYN;ADORA3 GO:0006955| immune response ZAP70;CTSS;MAP4K2;IKBKG;IKBKE GO:0016032| viral reproduction AXL;DYRK1A;EIF2AK4;SRC;HCK;RIPK1;EIF2AK2;TBK1;TYRO3;PAK2;FYN;LYN;SYK;EPHA2;IRAK1;LCK;KDR;PDGFRA;IKBKG GO:0016239| positive regulation of macroautophagy TBK1;IKBKG;KDR;PRKAA2 GO:0070423| nucleotide-binding oligomerization domain containing signaling pathway IRAK1;RIPK2;IKBKG;MAP2K6;IKBKB GO:0006355| regulation of transcription, DNA-dependent PDPK1;TXK;MAPK13;PKN1;MAPK14;PRKAA2;INSR;CSNK2A2;ERN1;HIPK2;IKBKG;CHEK2;ABL1;MAP2K6;PRKCQ;PRKAA1;ACVR1B;ERBB4;PAK6;FGFR1;PKN2;MAP3K9;CSNK2A1;HIPK3;EIF2AK2;ERBB2;TGFBR1;DAPK3;BTK GO:1901215| IKBKG;NTRK1;LRRK2;GSK3B GO:0050852| T cell receptor signaling pathway ITK;PAK3;IKBKB;BRAF;LCK;PRKCQ;IKBKG;CSK;PIK3CD;PAK2;FYN;RIPK2;ZAP70;PAK1;PDPK1;TXK 13662:[DB04998 DB14533] DB04998|AGRO100 IKBKG DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0016032| viral reproduction CFH;TP73;IKBKG;MDM2;TP53;APOA2;HDAC1;IDE;SIVA1 GO:0006955| immune response IL3;C1QC;C3;IGHA1;C8A;IGLV3-21;VTN;JCHAIN;IGKV1-17;IKBKG;C8B;C1R GO:0006954| inflammatory response KNG1;SERPINA3;IKBKG;BDKRB1;HDAC4;KRT16;C4B;S100A9;S100A8;KLKB1;C3;C5 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;APP;CLU;INS;AGT;S100A9;S100A8 GO:0006355| regulation of transcription, DNA-dependent PARP1;ESR1;HDAC8;INS;TP53;HDAC4;HDAC1;EEF1A1;ENO1;TP73;IKBKG GO:1901215| MT3;IKBKG;APOE;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;HDAC4;TP53;APP;IKBKG;TP73;ESR1;PARP1 GO:0009615| response to virus IKBKG;ENO1;CLU GO:0006974| response to DNA damage stimulus MPG;MGMT;PARP1;BRCC3;IKBKG;TP73;TP53 GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;PDIA3 GO:0045087| innate immune response JCHAIN;CFB;IKBKG;FGA;FCN3;CFH;IGHM;S100A7;KRT16;C8B;C1QB;APP;C1R;CLU;C4BPA;PGLYRP2;C4B;C8G;C1QC;CFI;C3;IGHA1;C5;C1S;APCS;C4BPB;S100A9;C8A;F12;APOL1;S100A8 GO:0006351| transcription, DNA-dependent HDAC4;EEF1A1;HDAC1;TP53;IKBKG;TP73;ENO1;ESR1;PARP1;HDAC8 GO:0051403| stress-activated MAPK cascade AGT;IKBKG GO:0016579| protein deubiquitination TP53;MDM2;IKBKG;BRCC3;ESR1 GO:0038095| IGLV3-21;IGKV1-17;IKBKG GO:0000187| activation of MAPK activity TP73;IKBKG;APP;SOD1;C5 GO:0006915| apoptotic process IKBKG;PDCD6;TP73;APLP1;TP53;APP;CLU;MT3;SIVA1;PARP1;S100A9;GSN;S100A8 13663:[DB04998 DB00690] DB04998|AGRO100 IKBKG DB00690|Flurazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP2E1;CYP2A6;CYP3A4;ABCB1;SLC22A2 common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG 13664:[DB04998 DB04846] DB04998|AGRO100 IKBKG DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 13665:[DB04998 DB01698] DB04998|AGRO100 IKBKG DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways 13666:[DB04998 DB00896] DB04998|AGRO100 IKBKG DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG 13667:[DB04998 DB00967] DB04998|AGRO100 IKBKG DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0006954| inflammatory response HRH1;IKBKG 13668:[DB04998 DB06789] DB04998|AGRO100 IKBKG DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PGR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG 13669:[DB04998 DB11827] DB04998|AGRO100 IKBKG DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways 13670:[DB04998 DB00584] DB04998|AGRO100 IKBKG DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes common pathways 13671:[DB04998 DB00485] DB04998|AGRO100 IKBKG DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways 13672:[DB04998 DB12070] DB04998|AGRO100 IKBKG DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways 13673:[DB04998 DB08934] DB04998|AGRO100 IKBKG DB08934|Sofosbuvir CTSA;HINT1;CMPK1;NME1;ABCB1;ABCG2 common genes common pathways GO:0006915| apoptotic process IKBKG;HINT1 GO:0006355| regulation of transcription, DNA-dependent HINT1;IKBKG GO:0006351| transcription, DNA-dependent HINT1;IKBKG 13674:[DB04998 DB00520] DB04998|AGRO100 IKBKG DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways 13675:[DB04998 DB05708] DB04998|AGRO100 IKBKG DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13676:[DB04998 DB00383] DB04998|AGRO100 IKBKG DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 13677:[DB04998 DB00616] DB04998|AGRO100 IKBKG DB00616|Candoxatril MME;ACE common genes common pathways 13678:[DB04998 DB00180] DB04998|AGRO100 IKBKG DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 13679:[DB04998 DB08960] DB04998|AGRO100 IKBKG DB08960|Hexamethonium CHRNA2 common genes common pathways 13680:[DB04998 DB13136] DB04998|AGRO100 IKBKG DB13136|Fluindione CYP2C9;CYP3A4 common genes common pathways 13681:[DB04998 DB06716] DB04998|AGRO100 IKBKG DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG 13682:[DB04998 DB11855] DB04998|AGRO100 IKBKG DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13683:[DB04998 DB00641] DB04998|AGRO100 IKBKG DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;ITGB2 GO:0006954| inflammatory response IKBKG;ITGB2;ITGAL GO:0006915| apoptotic process ITGB2;IKBKG 13684:[DB04998 DB12515] DB04998|AGRO100 IKBKG DB12515|9-aminocamptothecin CYP3A4 common genes common pathways 13685:[DB04998 DB01497] DB04998|AGRO100 IKBKG DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways GO:0016239| positive regulation of macroautophagy TRIM13;IKBKG GO:0006955| immune response OPRK1;IKBKG;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TRIM13;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TRIM13 GO:0045087| innate immune response TRIM13;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;POMC 13686:[DB04998 DB00264] DB04998|AGRO100 IKBKG DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 13687:[DB04998 DB00523] DB04998|AGRO100 IKBKG DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0006915| apoptotic process IKBKG;IGFBP3 GO:0006355| regulation of transcription, DNA-dependent CRABP2;RARA;RARG;RXRA;RXRB;RARB;RXRG;IKBKG GO:0016032| viral reproduction RXRA;IKBKG GO:0006351| transcription, DNA-dependent RARG;RARA;RXRA;RXRB;RXRG;IKBKG;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;RXRA;IKBKG;RXRG;RARB;RARG;RARA 13688:[DB04998 DB00259] DB04998|AGRO100 IKBKG DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways 13689:[DB04998 DB00683] DB04998|AGRO100 IKBKG DB00683|Midazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRB1;GABRB3;GABRB2;GABRA6;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP4B1;UGT1A4;CYP2E1;ABCB1;ABCB11 common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 13690:[DB04998 DB00306] DB04998|AGRO100 IKBKG DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG GO:1901215| IKBKG;GABRB2;GABRB3 13691:[DB04998 DB00288] DB04998|AGRO100 IKBKG DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006954| inflammatory response ANXA1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045087| innate immune response ANXA1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 13692:[DB04998 DB00279] DB04998|AGRO100 IKBKG DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0006351| transcription, DNA-dependent THRB;IKBKG;THRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;IKBKG;THRB GO:0006974| response to DNA damage stimulus IKBKG;PCNA GO:0006355| regulation of transcription, DNA-dependent THRA;IKBKG;THRB GO:0016032| viral reproduction SLC10A1;IKBKG 13693:[DB04998 DB04975] DB04998|AGRO100 IKBKG DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 13694:[DB04998 DB00818] DB04998|AGRO100 IKBKG DB00818|Propofol GABRB2;GABRB3;SCN4A;SCN2A;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP2B6;UGT1A8;UGT1A9;UGT1A1;FAAH;CYP2E1;CYP1B1;CYP1A1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;UGT1A6;ALB common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 GO:0009615| response to virus CYP1A1;IKBKG 13695:[DB04998 DB00636] DB04998|AGRO100 IKBKG DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARA GO:1901215| PPARA;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARA GO:0006351| transcription, DNA-dependent PPARA;IKBKG 13696:[DB04998 DB05115] DB04998|AGRO100 IKBKG DB05115|NN344 INSR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;INSR GO:0000187| activation of MAPK activity INSR;IKBKG 13697:[DB04998 DB06042] DB04998|AGRO100 IKBKG DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG 13698:[DB04998 DB14724] DB04998|AGRO100 IKBKG DB14724|Emapalumab IFNG common genes common pathways GO:0006915| apoptotic process IFNG;IKBKG GO:0006955| immune response IFNG;IKBKG GO:0009615| response to virus IFNG;IKBKG 13699:[DB04998 DB03425] DB04998|AGRO100 IKBKG DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways 13700:[DB04998 DB05849] DB04998|AGRO100 IKBKG DB05849|NCX 950 ADRB2 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13701:[DB04998 DB04445] DB04998|AGRO100 IKBKG DB04445|Mercuric iodide SULT2A1 common genes common pathways 13702:[DB04998 DB12923] DB04998|AGRO100 IKBKG DB12923|Gallopamil CYP3A4 common genes common pathways 13703:[DB04998 DB04934] DB04998|AGRO100 IKBKG DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways 13704:[DB04998 DB00751] DB04998|AGRO100 IKBKG DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0006955| immune response HRH2;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0006954| inflammatory response HRH1;IKBKG 13705:[DB04998 DB00765] DB04998|AGRO100 IKBKG DB00765|Metyrosine TH common genes common pathways 13706:[DB04998 DB05824] DB04998|AGRO100 IKBKG DB05824|CNS-5161 GRIN1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 13707:[DB04998 DB01109] DB04998|AGRO100 IKBKG DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0006355| regulation of transcription, DNA-dependent FGFR1;IKBKG GO:0006954| inflammatory response PF4;IKBKG;SELP GO:0006955| immune response PF4;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;FGFR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;FGF1;FGFR2;PF4;FGF4;HGF;IKBKG GO:0000187| activation of MAPK activity FGF2;FGF1;HGF;IKBKG GO:0006915| apoptotic process FGFR2;IKBKG 13708:[DB04998 DB00805] DB04998|AGRO100 IKBKG DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A 13709:[DB04998 DB06201] DB04998|AGRO100 IKBKG DB06201|Rufinamide GRM5;SCN9A;CES1;CYP2E1;CYP3A4;ALB common genes common pathways GO:0006954| inflammatory response SCN9A;IKBKG 13710:[DB04998 DB00199] DB04998|AGRO100 IKBKG DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways 13711:[DB04998 DB00374] DB04998|AGRO100 IKBKG DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0006915| apoptotic process IKBKG;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARD;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PPARD 13712:[DB04998 DB00958] DB04998|AGRO100 IKBKG DB00958|Carboplatin XDH;MPO;GSTT1;MT1A;MT2A;SOD1;GSTP1;GSTM1;NQO1;SLC31A1;SLC31A2;ATP7A;ATP7B;ABCG2;ABCC2 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;SOD1 13713:[DB04998 DB04880] DB04998|AGRO100 IKBKG DB04880|Enoximone PDE3A common genes common pathways 13714:[DB04998 DB00947] DB04998|AGRO100 IKBKG DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR1 GO:0006351| transcription, DNA-dependent IKBKG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG 13715:[DB04998 DB08899] DB04998|AGRO100 IKBKG DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;AR GO:0016579| protein deubiquitination IKBKG;AR 13716:[DB04998 DB01134] DB04998|AGRO100 IKBKG DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR3C2;IKBKG GO:0006351| transcription, DNA-dependent NR3C2;IKBKG 13717:[DB04998 DB00253] DB04998|AGRO100 IKBKG DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 13718:[DB04998 DB01323] DB04998|AGRO100 IKBKG DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways 13719:[DB04998 DB06781] DB04998|AGRO100 IKBKG DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 13720:[DB04998 DB00939] DB04998|AGRO100 IKBKG DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1;ALOX5 13721:[DB04998 DB01892] DB04998|AGRO100 IKBKG DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0006954| inflammatory response IKBKG;PTGS1;ALOX5 13722:[DB04998 DB06823] DB04998|AGRO100 IKBKG DB06823|Tiopronin MPO common genes common pathways 13723:[DB04998 DB00369] DB04998|AGRO100 IKBKG DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways 13724:[DB04998 DB06804] DB04998|AGRO100 IKBKG DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2 13725:[DB04998 DB00969] DB04998|AGRO100 IKBKG DB00969|Alosetron HTR3A;CYP2C9;CYP3A4;CYP1A2;CYP2E1 common genes common pathways 13726:[DB04998 DB12131] DB04998|AGRO100 IKBKG DB12131|Vinpocetine CYP3A4 common genes common pathways 13727:[DB04998 DB00826] DB04998|AGRO100 IKBKG DB00826|Natamycin CYP3A4 common genes common pathways 13728:[DB04998 DB04820] DB04998|AGRO100 IKBKG DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways 13729:[DB04998 DB06754] DB04998|AGRO100 IKBKG DB06754|Danaparoid SERPINC1 common genes common pathways 13730:[DB04998 DB13346] DB04998|AGRO100 IKBKG DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;HDAC10;HDAC6 GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;HDAC10;HDAC6 13731:[DB04998 DB11742] DB04998|AGRO100 IKBKG DB11742|Ebastine CYP3A4 common genes common pathways 13732:[DB04998 DB04920] DB04998|AGRO100 IKBKG DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways 13733:[DB04998 DB06742] DB04998|AGRO100 IKBKG DB06742|Ambroxol CYP3A4 common genes common pathways 13734:[DB04998 DB03546] DB04998|AGRO100 IKBKG DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 13735:[DB04998 DB00325] DB04998|AGRO100 IKBKG DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 13736:[DB04998 DB06218] DB04998|AGRO100 IKBKG DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways GO:0006954| inflammatory response SCN9A;IKBKG 13737:[DB04998 DB01006] DB04998|AGRO100 IKBKG DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways 13738:[DB04998 DB13931] DB04998|AGRO100 IKBKG DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0006915| apoptotic process ROCK1;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade ROCK2;ROCK1;IKBKG 13739:[DB04998 DB07879] DB04998|AGRO100 IKBKG DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent HDAC4;IKBKG GO:0006954| inflammatory response HDAC4;IKBKG GO:0006351| transcription, DNA-dependent HDAC4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;HDAC4 13740:[DB04998 DB00257] DB04998|AGRO100 IKBKG DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;NR1I2;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR1I2;NR1I3 GO:0006955| immune response IKBKG;CYP11B1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2;NR1I3 13741:[DB04998 DB08865] DB04998|AGRO100 IKBKG DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;ALK GO:0000187| activation of MAPK activity IKBKG;ALK 13742:[DB04998 DB00602] DB04998|AGRO100 IKBKG DB00602|Ivermectin GLRA3;GABRB3;CYP3A4;ABCB1;ABCC1;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:1901215| IKBKG;GABRB3 13743:[DB04998 DB00155] DB04998|AGRO100 IKBKG DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PADI4;IKBKG GO:0006351| transcription, DNA-dependent PADI4;IKBKG GO:0045087| innate immune response PADI4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;IKBKG 13744:[DB04998 DB08813] DB04998|AGRO100 IKBKG DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0038095| IKBKG;FOS GO:0016579| protein deubiquitination IKBKG;MYC GO:0006355| regulation of transcription, DNA-dependent FOS;IKBKG;MYC GO:0006954| inflammatory response SELP;FOS;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;MYC GO:0045944| positive regulation of transcription from RNA polymerase II promoter FOS;IKBKG;MYC GO:0006974| response to DNA damage stimulus IKBKG;MYC 13745:[DB04998 DB09082] DB04998|AGRO100 IKBKG DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13746:[DB04998 DB00055] DB04998|AGRO100 IKBKG DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;PF4;IKBKG GO:0006955| immune response PF4;IKBKG GO:0006954| inflammatory response PF4;IKBKG 13747:[DB04998 DB01359] DB04998|AGRO100 IKBKG DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0006954| inflammatory response IKBKG;ORM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13748:[DB04998 DB00281] DB04998|AGRO100 IKBKG DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG;SCN9A GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IKBKG 13749:[DB04998 DB00524] DB04998|AGRO100 IKBKG DB00524|Metolazone SLC12A3 common genes common pathways 13750:[DB04998 DB01110] DB04998|AGRO100 IKBKG DB01110|Miconazole NOS3;NOS2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;KCNH2;KCNH6;KCNH7;NR1I2;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP11B1;CYP51A1;CYP19A1;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 GO:0006955| immune response CYP11B1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG 13751:[DB04998 DB04884] DB04998|AGRO100 IKBKG DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways 13752:[DB04998 DB13981] DB04998|AGRO100 IKBKG DB13981|Nomegestrol acetate CYP3A4 common genes common pathways 13753:[DB04998 DB09017] DB04998|AGRO100 IKBKG DB09017|Brotizolam CYP3A4 common genes common pathways 13754:[DB04998 DB09121] DB04998|AGRO100 IKBKG DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways 13755:[DB04998 DB03010] DB04998|AGRO100 IKBKG DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 13756:[DB04998 DB00323] DB04998|AGRO100 IKBKG DB00323|Tolcapone COMT;CYP2C9 common genes common pathways 13757:[DB04998 DB00924] DB04998|AGRO100 IKBKG DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A 13758:[DB04998 DB01591] DB04998|AGRO100 IKBKG DB01591|Solifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13759:[DB04998 DB13158] DB04998|AGRO100 IKBKG DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0006915| apoptotic process NR3C1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 13760:[DB04998 DB08893] DB04998|AGRO100 IKBKG DB08893|Mirabegron ADRB3;CYP3A4;CYP2D6;BCHE;ALB;ORM1;ABCB1;SLCO1A2 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 13761:[DB04998 DB05416] DB04998|AGRO100 IKBKG DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;PPARD;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;IKBKG GO:1901215| IKBKG;PPARA GO:0006915| apoptotic process IKBKG;PPARD 13762:[DB04998 DB06433] DB04998|AGRO100 IKBKG DB06433|Tezacitabine RRM1;TYMP common genes common pathways 13763:[DB04998 DB00548] DB04998|AGRO100 IKBKG DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways 13764:[DB04998 DB00406] DB04998|AGRO100 IKBKG DB00406|Gentian violet cation SLC22A1 common genes common pathways 13765:[DB04998 DB09401] DB04998|AGRO100 IKBKG DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0006915| apoptotic process BCL2;MCL1;IKBKG;BCL2L1 GO:0006974| response to DNA damage stimulus BCL2;IKBKG GO:0009615| response to virus BCL2L1;IKBKG 13766:[DB04998 DB05309] DB04998|AGRO100 IKBKG DB05309|TP-508 FGF4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;FGF4 13767:[DB04998 DB05050] DB04998|AGRO100 IKBKG DB05050|ADL5859 OPRD1 common genes common pathways GO:0006955| immune response IKBKG;OPRD1 13768:[DB04998 DB07348] DB04998|AGRO100 IKBKG DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways 13769:[DB04998 DB00929] DB04998|AGRO100 IKBKG DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways GO:0006955| immune response IKBKG;PTGER4 GO:0007254| JNK cascade PTGER4;IKBKG 13770:[DB04998 DB07246] DB04998|AGRO100 IKBKG DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 13771:[DB04998 DB13385] DB04998|AGRO100 IKBKG DB13385|Dihydroergocryptine CYP3A4 common genes common pathways 13772:[DB04998 DB08810] DB04998|AGRO100 IKBKG DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG 13773:[DB04998 DB01000] DB04998|AGRO100 IKBKG DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 13774:[DB04998 DB06154] DB04998|AGRO100 IKBKG DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways 13775:[DB04998 DB06268] DB04998|AGRO100 IKBKG DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways 13776:[DB04998 DB09234] DB04998|AGRO100 IKBKG DB09234|Darodipine CYP3A4 common genes common pathways 13777:[DB04998 DB08916] DB04998|AGRO100 IKBKG DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways GO:0006915| apoptotic process ERBB4;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ERBB4;ERBB2 GO:0006351| transcription, DNA-dependent ERBB2;ERBB4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IKBKG 13778:[DB04998 DB08884] DB04998|AGRO100 IKBKG DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways 13779:[DB04998 DB05458] DB04998|AGRO100 IKBKG DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways 13780:[DB04998 DB05109] DB04998|AGRO100 IKBKG DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1 13781:[DB04998 DB01437] DB04998|AGRO100 IKBKG DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 13782:[DB04998 DB06204] DB04998|AGRO100 IKBKG DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0006955| immune response OPRK1;IKBKG;OPRD1 13783:[DB04998 DB09028] DB04998|AGRO100 IKBKG DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 13784:[DB04998 DB00744] DB04998|AGRO100 IKBKG DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0006954| inflammatory response IKBKG;ALOX5;PTGS1 13785:[DB04998 DB00452] DB04998|AGRO100 IKBKG DB00452|Framycetin rpsL;CXCR4 common genes common pathways GO:0016032| viral reproduction CXCR4;IKBKG GO:0006954| inflammatory response IKBKG;CXCR4 GO:0009615| response to virus CXCR4;IKBKG GO:0000187| activation of MAPK activity IKBKG;CXCR4 GO:0006915| apoptotic process IKBKG;CXCR4 13786:[DB04998 DB00937] DB04998|AGRO100 IKBKG DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways 13787:[DB04998 DB13191] DB04998|AGRO100 IKBKG DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways 13788:[DB04998 DB06186] DB04998|AGRO100 IKBKG DB06186|Ipilimumab CTLA4 common genes common pathways GO:0006974| response to DNA damage stimulus CTLA4;IKBKG GO:0006955| immune response CTLA4;IKBKG 13789:[DB04998 DB00247] DB04998|AGRO100 IKBKG DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B 13790:[DB04998 DB03515] DB04998|AGRO100 IKBKG DB03515|Equilenin CYP3A4 common genes common pathways 13791:[DB04998 DB05260] DB04998|AGRO100 IKBKG DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IKBKG;TFR2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;IKBKG GO:0016032| viral reproduction IKBKG;TFRC GO:0006955| immune response IL1B;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;IKBKG GO:0006954| inflammatory response IL1B;IKBKG GO:0006915| apoptotic process IKBKG;IL1B GO:0000187| activation of MAPK activity IL1B;IKBKG 13792:[DB04998 DB04977] DB04998|AGRO100 IKBKG DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways 13793:[DB04998 DB01239] DB04998|AGRO100 IKBKG DB01239|Chlorprothixene DRD2;DRD1;DRD3;HTR2A;HTR2B;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ABCB1 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 GO:0016032| viral reproduction HTR2A;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0009615| response to virus IKBKG;CHRM2 13794:[DB04998 DB00724] DB04998|AGRO100 IKBKG DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade TLR8;IKBKG GO:0006954| inflammatory response TLR7;TLR8;IKBKG GO:0006955| immune response IKBKG;TLR7 GO:0045087| innate immune response TLR8;IKBKG;TLR7 GO:0009615| response to virus TLR8;IKBKG 13795:[DB04998 DB06271] DB04998|AGRO100 IKBKG DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 13796:[DB04998 DB00367] DB04998|AGRO100 IKBKG DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR;ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR;ESR1;AR GO:0006351| transcription, DNA-dependent ESR1;AR;IKBKG;PGR 13797:[DB04998 DB00364] DB04998|AGRO100 IKBKG DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways GO:0045087| innate immune response FGB;FGA;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;FGF2 GO:0000187| activation of MAPK activity EGF;FGF2;IKBKG 13798:[DB04998 DB13956] DB04998|AGRO100 IKBKG DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006915| apoptotic process GPER1;BECN1;IKBKG GO:0016579| protein deubiquitination BECN1;IKBKG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;NR1I2;ESRRG;IKBKG;ESR2 GO:0006954| inflammatory response IKBKG;GPER1 GO:0016032| viral reproduction BECN1;IKBKG GO:0006351| transcription, DNA-dependent ESRRG;IKBKG;ESR2;NCOA2;NR1I2;ESR1 GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;ESR2;IKBKG;NCOA2;NR1I2;GPER1;ESR1 GO:0045087| innate immune response IKBKG;GPER1 13799:[DB04998 DB01193] DB04998|AGRO100 IKBKG DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13800:[DB04998 DB01624] DB04998|AGRO100 IKBKG DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0006954| inflammatory response IKBKG;HRH1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 13801:[DB04998 DB03552] DB04998|AGRO100 IKBKG DB03552|3-Tyrosine TH common genes common pathways 13802:[DB04998 DB00171] DB04998|AGRO100 IKBKG DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0006351| transcription, DNA-dependent CSNK2A1;PPP5C;PRKAA1;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ABL1;PPP5C GO:0006974| response to DNA damage stimulus AKT1;PPP5C;IKBKG;ABL1 GO:0045087| innate immune response PIK3CA;ABL2;TNK2;IKBKG;ABL1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ACVRL1;ACVR1B;ACVR1;AKT1;IKBKG GO:1901215| IKBKG;AKT1;PPP5C GO:0050852| T cell receptor signaling pathway IKBKG;PIK3CA GO:0006355| regulation of transcription, DNA-dependent ACVR1B;ACVRL1;CSNK2A1;ABCG1;IKBKG;ABL1;PRKAA1 GO:0016032| viral reproduction IKBKG;SLC25A4 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;ALK GO:0006954| inflammatory response IKBKG;AKT1;PIK3CA GO:0043276| anoikis IKBKG;AKT1;PIK3CA GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;AKT1 GO:0000187| activation of MAPK activity ALK;PRKAA1;IKBKG GO:0006915| apoptotic process AKT1;CSNK2A1;NAE1;APAF1;IKBKG;ABL1 GO:0038095| PIK3CA;IKBKG GO:0016579| protein deubiquitination CFTR;IKBKG 13803:[DB04998 DB05766] DB04998|AGRO100 IKBKG DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG 13804:[DB04998 DB08883] DB04998|AGRO100 IKBKG DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways 13805:[DB04998 DB00352] DB04998|AGRO100 IKBKG DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways 13806:[DB04998 DB00445] DB04998|AGRO100 IKBKG DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;CHD1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;CHD1 13807:[DB04998 DB06738] DB04998|AGRO100 IKBKG DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 GO:0006954| inflammatory response IKBKG;PTGS1 GO:0006955| immune response OPRK1;IKBKG;OPRD1 13808:[DB04998 DB09215] DB04998|AGRO100 IKBKG DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 13809:[DB04998 DB05223] DB04998|AGRO100 IKBKG DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0016032| viral reproduction HDAC1;IKBKG GO:0006355| regulation of transcription, DNA-dependent HDAC2;HDAC3;HDAC6;IKBKG;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;HDAC3;IKBKG;HDAC1 GO:0006351| transcription, DNA-dependent HDAC3;HDAC2;HDAC6;IKBKG;HDAC1 13810:[DB04998 DB12698] DB04998|AGRO100 IKBKG DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0000187| activation of MAPK activity CXCR4;IKBKG GO:0006915| apoptotic process IKBKG;CXCR4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;CD4 GO:0009615| response to virus CXCR4;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;CD4 GO:0016032| viral reproduction CD4;CXCR4;IKBKG;CCR5 GO:0006955| immune response CD4;CCR5;IKBKG GO:0006954| inflammatory response CCR5;IKBKG;CXCR4 13811:[DB04998 DB01597] DB04998|AGRO100 IKBKG DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0006915| apoptotic process IKBKG;DPEP1 13812:[DB04998 DB00031] DB04998|AGRO100 IKBKG DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0045087| innate immune response FGA;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent CALR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;SERPINE1 GO:0016032| viral reproduction IKBKG;KRT8 GO:0006355| regulation of transcription, DNA-dependent CALR;IKBKG 13813:[DB04998 DB00642] DB04998|AGRO100 IKBKG DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways 13814:[DB04998 DB02187] DB04998|AGRO100 IKBKG DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG GO:0006351| transcription, DNA-dependent ESR1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG 13815:[DB04998 DB01207] DB04998|AGRO100 IKBKG DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0006954| inflammatory response IKBKG;TBXA2R 13816:[DB04998 DB00043] DB04998|AGRO100 IKBKG DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways GO:0038095| FCER1A;IKBKG;MS4A2 GO:0006955| immune response MS4A2;IKBKG GO:0006954| inflammatory response MS4A2;IKBKG 13817:[DB04998 DB01194] DB04998|AGRO100 IKBKG DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways 13818:[DB04998 DB09343] DB04998|AGRO100 IKBKG DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways 13819:[DB04998 DB00240] DB04998|AGRO100 IKBKG DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006915| apoptotic process IKBKG;NR3C1 13820:[DB04998 DB00954] DB04998|AGRO100 IKBKG DB00954|Dirithromycin CYP3A4 common genes common pathways 13821:[DB04998 DB08910] DB04998|AGRO100 IKBKG DB08910|Pomalidomide CRBN;TNF;PTGS2;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;TNF GO:0007254| JNK cascade TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TNF GO:0006954| inflammatory response IKBKG;TNF;PTGS2 GO:0006955| immune response TNF;IKBKG GO:0009615| response to virus TNF;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IKBKG 13822:[DB04998 DB00860] DB04998|AGRO100 IKBKG DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 13823:[DB04998 DB06176] DB04998|AGRO100 IKBKG DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes common pathways GO:0006954| inflammatory response IKBKG;HDAC4 GO:0016032| viral reproduction IKBKG;HDAC1 GO:0006355| regulation of transcription, DNA-dependent HDAC6;HDAC2;HDAC1;HDAC4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;HDAC4;IKBKG;HDAC2 GO:0009615| response to virus IKBKG;CYP1A1 GO:0006351| transcription, DNA-dependent IKBKG;HDAC4;HDAC1;HDAC2;HDAC6 13824:[DB04998 DB00846] DB04998|AGRO100 IKBKG DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006915| apoptotic process NR3C1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG 13825:[DB04998 DB06209] DB04998|AGRO100 IKBKG DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes common pathways 13826:[DB04998 DB01125] DB04998|AGRO100 IKBKG DB01125|Anisindione GGCX common genes common pathways 13827:[DB04998 DB00748] DB04998|AGRO100 IKBKG DB00748|Carbinoxamine HRH1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0006954| inflammatory response HRH1;IKBKG 13828:[DB04998 DB01606] DB04998|AGRO100 IKBKG DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways 13829:[DB04998 DB00851] DB04998|AGRO100 IKBKG DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 13830:[DB04998 DB00481] DB04998|AGRO100 IKBKG DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ESR1 GO:0006915| apoptotic process IKBKG;SERPINB9 GO:0006955| immune response SERPINB9;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG;ESR2 GO:0006351| transcription, DNA-dependent ESR1;ESR2;IKBKG 13831:[DB04998 DB01009] DB04998|AGRO100 IKBKG DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 13832:[DB04998 DB01536] DB04998|AGRO100 IKBKG DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways 13833:[DB04998 DB12498] DB04998|AGRO100 IKBKG DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0006915| apoptotic process CXCR4;IKBKG GO:0000187| activation of MAPK activity CXCR4;IKBKG GO:0006954| inflammatory response IKBKG;CXCR4 GO:0016032| viral reproduction CXCR4;IKBKG GO:0009615| response to virus CXCR4;IKBKG 13834:[DB04998 DB11967] DB04998|AGRO100 IKBKG DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0007254| JNK cascade TNF;IKBKG GO:0006915| apoptotic process IKBKG;IL1B GO:0000187| activation of MAPK activity MAP2K2;TNF;IKBKG;IL1B GO:0038095| MAP3K1;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0006954| inflammatory response IL1B;IKBKG;IL6;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IL6;IL1B;IKBKG GO:0006955| immune response TNF;IL6;IKBKG;IL1B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IL1B;IKBKG GO:0009615| response to virus TNF;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IKBKG;IL6;TNF 13835:[DB04998 DB00629] DB04998|AGRO100 IKBKG DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B 13836:[DB04998 DB01632] DB04998|AGRO100 IKBKG DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0016032| viral reproduction UCKL1;IKBKG 13837:[DB04998 DB00562] DB04998|AGRO100 IKBKG DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways 13838:[DB04998 DB05812] DB04998|AGRO100 IKBKG DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 13839:[DB04998 DB01370] DB04998|AGRO100 IKBKG DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0045087| innate immune response APP;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;IKBKG GO:1901215| APP;IKBKG GO:0006915| apoptotic process IKBKG;APP GO:0000187| activation of MAPK activity IKBKG;APP 13840:[DB04998 DB01114] DB04998|AGRO100 IKBKG DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 13841:[DB04998 DB08905] DB04998|AGRO100 IKBKG DB08905|Formestane CYP3A4 common genes common pathways 13842:[DB04998 DB00054] DB04998|AGRO100 IKBKG DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:0016032| viral reproduction FCGR2B;IKBKG;ITGB3 GO:0006955| immune response VTN;FCGR3A;FCGR2C;C1QC;C1R;FCGR2B;FCGR3B;IKBKG;FCGR1A GO:0006954| inflammatory response FCGR2B;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;FCGR1A GO:0045087| innate immune response C1S;C1QC;C1QA;C1R;C1QB;IKBKG;FCGR1A 13843:[DB04998 DB01277] DB04998|AGRO100 IKBKG DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0006955| immune response IGF1R;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;INSR GO:0000187| activation of MAPK activity INSR;IKBKG GO:0006915| apoptotic process IKBKG;IGFBP3 13844:[DB04998 DB00461] DB04998|AGRO100 IKBKG DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 13845:[DB04998 DB02746] DB04998|AGRO100 IKBKG DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RXRB;RXRA;PPARG;IKBKG;RXRG;ESR2;PGR;PPARA;ESR1;PPARD GO:1901215| IKBKG;PPARA GO:0016032| viral reproduction RXRA;IKBKG GO:0006351| transcription, DNA-dependent PPARD;ESR1;PPARA;PPARG;RXRB;RXRA;PGR;IKBKG;ESR2;RXRG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;RXRA;PPARG;PGR;IKBKG;ESR2;RXRG;ESR1;PPARA GO:0045087| innate immune response PPARG;IKBKG GO:0006915| apoptotic process IKBKG;PPARD GO:0016579| protein deubiquitination IKBKG;ESR1 13846:[DB04998 DB14060] DB04998|AGRO100 IKBKG DB14060|NS-398 PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG 13847:[DB04998 DB00005] DB04998|AGRO100 IKBKG DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TNF GO:0006954| inflammatory response IKBKG;TNFRSF1B;FCGR2B;TNF GO:0006955| immune response FCGR2C;FCGR3A;C1QC;C1R;LTA;TNF;FCGR3B;FCGR2B;FCGR1A;IKBKG;TNFRSF1B GO:0016032| viral reproduction FCGR2B;IKBKG GO:0045087| innate immune response C1QA;C1QC;C1S;FCGR1A;IKBKG;C1R;C1QB GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0009615| response to virus TNF;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0006915| apoptotic process LTA;IKBKG;TNFRSF1B GO:0000187| activation of MAPK activity TNF;IKBKG GO:0007254| JNK cascade IKBKG;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG 13848:[DB04998 DB01180] DB04998|AGRO100 IKBKG DB01180|Rescinnamine ACE common genes common pathways 13849:[DB04998 DB00310] DB04998|AGRO100 IKBKG DB00310|Chlorthalidone SLC12A1 common genes common pathways 13850:[DB04998 DB00216] DB04998|AGRO100 IKBKG DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0006954| inflammatory response PTGS1;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG 13851:[DB04998 DB00975] DB04998|AGRO100 IKBKG DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 GO:0006355| regulation of transcription, DNA-dependent RCAN1;IKBKG 13852:[DB04998 DB00528] DB04998|AGRO100 IKBKG DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways 13853:[DB04998 DB12537] DB04998|AGRO100 IKBKG DB12537|Benzodiazepine CYP3A4 common genes common pathways 13854:[DB04998 DB12589] DB04998|AGRO100 IKBKG DB12589|Dacetuzumab CD40 common genes common pathways GO:0006954| inflammatory response CD40;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;CD40 GO:0006955| immune response IKBKG;CD40 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CD40;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD40;IKBKG 13855:[DB04998 DB04886] DB04998|AGRO100 IKBKG DB04886|Calanolide A CYP3A4 common genes common pathways 13856:[DB04998 DB07615] DB04998|AGRO100 IKBKG DB07615|Tranilast HPGDS;CYP3A4;CYP2C9 common genes common pathways 13857:[DB04998 DB05075] DB04998|AGRO100 IKBKG DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0050852| T cell receptor signaling pathway IKBKG;CSK GO:0016239| positive regulation of macroautophagy KDR;IKBKG GO:0016032| viral reproduction KDR;IKBKG GO:0045087| innate immune response IKBKG;CSK 13858:[DB04998 DB05095] DB04998|AGRO100 IKBKG DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2 13859:[DB04998 DB01100] DB04998|AGRO100 IKBKG DB01100|Pimozide DRD2;DRD3;KCNH2;CALM1;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0038095| IKBKG;CALM1 13860:[DB04998 DB00067] DB04998|AGRO100 IKBKG DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;IKBKG 13861:[DB04998 DB00983] DB04998|AGRO100 IKBKG DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 13862:[DB04998 DB02902] DB04998|AGRO100 IKBKG DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways 13863:[DB04998 DB00789] DB04998|AGRO100 IKBKG DB00789|Gadopentetic acid PGD common genes common pathways 13864:[DB04998 DB04599] DB04998|AGRO100 IKBKG DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 13865:[DB04998 DB01667] DB04998|AGRO100 IKBKG DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0006955| immune response IKBKG;PNP 13866:[DB04998 DB00282] DB04998|AGRO100 IKBKG DB00282|Pamidronate FDPS common genes common pathways GO:0016032| viral reproduction FDPS;IKBKG 13867:[DB04998 DB00935] DB04998|AGRO100 IKBKG DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 13868:[DB04998 DB01341] DB04998|AGRO100 IKBKG DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways 13869:[DB04998 DB00763] DB04998|AGRO100 IKBKG DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways 13870:[DB04998 DB08868] DB04998|AGRO100 IKBKG DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;IKBKG GO:0006355| regulation of transcription, DNA-dependent HDAC1;IKBKG GO:0006954| inflammatory response IKBKG;SPHK1 GO:0051092| positive regulation of NF-kappaB transcription factor activity SPHK1;IKBKG GO:0016032| viral reproduction IKBKG;HDAC1 GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway SPHK1;IKBKG 13871:[DB04998 DB09274] DB04998|AGRO100 IKBKG DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways 13872:[DB04998 DB00575] DB04998|AGRO100 IKBKG DB00575|Clonidine ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP3A5;SLC22A3;SLC22A5;SLC22A4;ABCB1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0006915| apoptotic process IKBKG;ADRA1A GO:0009615| response to virus IKBKG;CYP1A1 13873:[DB04998 DB11919] DB04998|AGRO100 IKBKG DB11919|6-O-benzylguanine CYP3A4 common genes common pathways 13874:[DB04998 DB08907] DB04998|AGRO100 IKBKG DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG 13875:[DB04998 DB12248] DB04998|AGRO100 IKBKG DB12248|Tulobuterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 13876:[DB04998 DB11575] DB04998|AGRO100 IKBKG DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 13877:[DB04998 DB08881] DB04998|AGRO100 IKBKG DB08881|Vemurafenib BRAF;CYP1A2;CYP2D6;CYP3A4;CYP2C9;CYP2C8;CYP2B6;ALB;ORM1;ABCC1;ABCG2 common genes common pathways GO:0050852| T cell receptor signaling pathway BRAF;IKBKG GO:0006954| inflammatory response ORM1;IKBKG 13878:[DB04998 DB11327] DB04998|AGRO100 IKBKG DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2 13879:[DB04998 DB14542] DB04998|AGRO100 IKBKG DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006954| inflammatory response ANXA1;IKBKG GO:0006955| immune response IKBKG;CYP11B1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0045087| innate immune response IKBKG;ANXA1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006915| apoptotic process NR3C1;IKBKG 13880:[DB04998 DB00626] DB04998|AGRO100 IKBKG DB00626|Bacitracin IDE;A2M common genes common pathways GO:0016032| viral reproduction IDE;IKBKG 13881:[DB04998 DB00541] DB04998|AGRO100 IKBKG DB00541|Vincristine TUBB;TUBA4A;CYP3A5;CYP3A7;CYP3A4;ABCB1;ABCC3;SLC22A3;ABCC1;ABCC10;ABCC2;ABCB11;ABCG2;RALBP1;SLCO1B1;SLCO1B3 common genes common pathways 13882:[DB04998 DB11574] DB04998|AGRO100 IKBKG DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways 13883:[DB04998 DB00583] DB04998|AGRO100 IKBKG DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways 13884:[DB04998 DB05212] DB04998|AGRO100 IKBKG DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB1;IKBKG;NFKB2 GO:0038095| IKBKG;NFKB1 GO:0006915| apoptotic process IKBKG;NFKB1 GO:0006351| transcription, DNA-dependent NFKB1;NFKB2;IKBKG GO:0051403| stress-activated MAPK cascade IKBKG;NFKB1 GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;NFKB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;NFKB2;IKBKG GO:0045087| innate immune response NFKB1;IKBKG;NFKB2 GO:0006355| regulation of transcription, DNA-dependent IKBKG;NFKB2;NFKB1 GO:0050852| T cell receptor signaling pathway NFKB1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB2;IKBKG;NFKB1 GO:0006954| inflammatory response NFKB1;NFKB2;IKBKG 13885:[DB04998 DB11828] DB04998|AGRO100 IKBKG DB11828|Neratinib EGFR;CYP3A4;FMO3;ALB;ORM1;ORM2;ABCB1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IKBKG 13886:[DB04998 DB05281] DB04998|AGRO100 IKBKG DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0006915| apoptotic process IKBKG;BCL2 GO:0006974| response to DNA damage stimulus BCL2;IKBKG 13887:[DB04998 DB00158] DB04998|AGRO100 IKBKG DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0006954| inflammatory response IKBKG;FOLR2 13888:[DB04998 DB04356] DB04998|AGRO100 IKBKG DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways 13889:[DB04998 DB00901] DB04998|AGRO100 IKBKG DB00901|Bitolterol ADRB2 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13890:[DB04998 DB01041] DB04998|AGRO100 IKBKG DB01041|Thalidomide CRBN;TNF;NFKB1;FGFR2;PTGS2;ORM1;ORM2;CYP2C19;CYP1A1;CYP2E1;CYP2C9;PTGS1;PTGS2;CYP3A5 common genes common pathways GO:0051403| stress-activated MAPK cascade NFKB1;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway NFKB1;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NFKB1 GO:0009615| response to virus IKBKG;CYP1A1;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;NFKB1;IKBKG;TNF GO:0045087| innate immune response NFKB1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NFKB1;IKBKG GO:0050852| T cell receptor signaling pathway NFKB1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;TNF;IKBKG GO:0006954| inflammatory response PTGS2;NFKB1;PTGS1;TNF;ORM1;IKBKG GO:0006955| immune response TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG;NFKB1 GO:0038095| NFKB1;IKBKG GO:0006915| apoptotic process NFKB1;FGFR2;IKBKG GO:0000187| activation of MAPK activity TNF;IKBKG GO:0007254| JNK cascade IKBKG;TNF 13891:[DB04998 DB01303] DB04998|AGRO100 IKBKG DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0006915| apoptotic process ADORA2A;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ADORA2A;HDAC2 GO:0006954| inflammatory response ADORA1;ADORA2A;IKBKG GO:0006351| transcription, DNA-dependent HDAC2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;IKBKG 13892:[DB04998 DB08341] DB04998|AGRO100 IKBKG DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0006915| apoptotic process PTK2B;IKBKG GO:0045087| innate immune response PTK2B;IKBKG 13893:[DB04998 DB00234] DB04998|AGRO100 IKBKG DB00234|Reboxetine SLC6A2;CYP3A4;CYP2D6;ABCB1 common genes common pathways 13894:[DB04998 DB00535] DB04998|AGRO100 IKBKG DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 13895:[DB04998 DB13456] DB04998|AGRO100 IKBKG DB13456|Midecamycin CYP3A4 common genes common pathways 13896:[DB04998 DB11799] DB04998|AGRO100 IKBKG DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;POU2F2 GO:0006351| transcription, DNA-dependent POU2F2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;POU2F2 13897:[DB04998 DB12329] DB04998|AGRO100 IKBKG DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways 13898:[DB04998 DB01365] DB04998|AGRO100 IKBKG DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process ADRA1A;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13899:[DB04998 DB01011] DB04998|AGRO100 IKBKG DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways GO:0006955| immune response IKBKG;CYP11B1 13900:[DB04998 DB00219] DB04998|AGRO100 IKBKG DB00219|Oxyphenonium CHRM1 common genes common pathways 13901:[DB04998 DB13928] DB04998|AGRO100 IKBKG DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways 13902:[DB04998 DB06800] DB04998|AGRO100 IKBKG DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1 13903:[DB04998 DB13139] DB04998|AGRO100 IKBKG DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 13904:[DB04998 DB01152] DB04998|AGRO100 IKBKG DB01152|Candicidin CYP3A4 common genes common pathways 13905:[DB04998 DB00313] DB04998|AGRO100 IKBKG DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes common pathways GO:0006915| apoptotic process IKBKG;PPARD GO:0006351| transcription, DNA-dependent PPARG;IKBKG;PPARA;PPARD;HDAC2;HDAC9 GO:0045087| innate immune response PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;PPARA;IKBKG;PPARG GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARD;HDAC9;HDAC2;PPARG;IKBKG GO:0006954| inflammatory response IKBKG;HDAC9;PTGS1;SCN9A 13906:[DB04998 DB00354] DB04998|AGRO100 IKBKG DB00354|Buclizine HRH1;CHRM1 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 13907:[DB04998 DB00476] DB04998|AGRO100 IKBKG DB00476|Duloxetine SLC6A4;SLC6A2;SLC6A3;CYP1A2;CYP2D6;CYP3A4 common genes common pathways 13908:[DB04998 DB11963] DB04998|AGRO100 IKBKG DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IKBKG 13909:[DB04998 DB00586] DB04998|AGRO100 IKBKG DB00586|Diclofenac PTGS2;PTGS1;ALOX5;SCN4A;ASIC1;KCNQ2;KCNQ3;PLA2G2A;CYP2C9;CYP2C19;CYP1A2;CYP2C8;UGT1A1;UGT2B7;PTGS1;CYP3A4;CYP1A1;CYP2B6;CYP2C18;CYP2E1;TTR;ALB;ABCC4;ABCB1;ABCC1;SLC22A6;SLC22A8;SLCO1C1;SLC22A11;SLCO1B1;ABCB11 common genes common pathways GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;IKBKG GO:0009615| response to virus CYP1A1;IKBKG 13910:[DB04998 DB14512] DB04998|AGRO100 IKBKG DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PGR;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG;PGR GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG;PGR 13911:[DB04998 DB00185] DB04998|AGRO100 IKBKG DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways 13912:[DB04998 DB01419] DB04998|AGRO100 IKBKG DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 13913:[DB04998 DB09123] DB04998|AGRO100 IKBKG DB09123|Dienogest PGR;AR;CYP3A4 common genes common pathways GO:0016579| protein deubiquitination AR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;IKBKG GO:0006351| transcription, DNA-dependent AR;PGR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent PGR;IKBKG;AR 13914:[DB04998 DB00887] DB04998|AGRO100 IKBKG DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0016579| protein deubiquitination IKBKG;CFTR GO:0006954| inflammatory response IKBKG;PTGS2 GO:0016032| viral reproduction SLC10A1;IKBKG 13915:[DB04998 DB09325] DB04998|AGRO100 IKBKG DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 13916:[DB04998 DB00115] DB04998|AGRO100 IKBKG DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways 13917:[DB04998 DB06626] DB04998|AGRO100 IKBKG DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0016032| viral reproduction IKBKG;KDR GO:0016239| positive regulation of macroautophagy IKBKG;KDR 13918:[DB04998 DB06454] DB04998|AGRO100 IKBKG DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 13919:[DB04998 DB14126] DB04998|AGRO100 IKBKG DB14126|Tenofovir ABCB1 common genes common pathways 13920:[DB04998 DB00677] DB04998|AGRO100 IKBKG DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways 13921:[DB04998 DB00136] DB04998|AGRO100 IKBKG DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;VDR;HOXA10 GO:0006351| transcription, DNA-dependent IKBKG;VDR;HOXA10 GO:0006355| regulation of transcription, DNA-dependent VDR;HOXA10;IKBKG 13922:[DB04998 DB00776] DB04998|AGRO100 IKBKG DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes common pathways 13923:[DB04998 DB11323] DB04998|AGRO100 IKBKG DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 13924:[DB04998 DB14544] DB04998|AGRO100 IKBKG DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006954| inflammatory response IKBKG;ANXA1 GO:0006955| immune response IKBKG;CYP11B1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0045087| innate immune response IKBKG;ANXA1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 13925:[DB04998 DB14481] DB04998|AGRO100 IKBKG DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0007254| JNK cascade CASR;IKBKG GO:0006915| apoptotic process CASR;PDCD6;CIB1;IKBKG GO:0038095| CALM1;IKBKG GO:0016032| viral reproduction SLC20A2;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity CIB1;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;CACNB3 GO:0006355| regulation of transcription, DNA-dependent CALR;IKBKG GO:0006974| response to DNA damage stimulus CIB1;IKBKG GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent CALR;IKBKG GO:0045087| innate immune response IKBKG;S100B GO:0009615| response to virus TPT1;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;S100B;S100A13;SLC20A1 13926:[DB04998 DB09308] DB04998|AGRO100 IKBKG DB09308|Solithromycin CYP3A4 common genes common pathways 13927:[DB04998 DB00017] DB04998|AGRO100 IKBKG DB00017|Salmon Calcitonin CALCR common genes common pathways 13928:[DB04998 DB05266] DB04998|AGRO100 IKBKG DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0050852| T cell receptor signaling pathway PDE4B;IKBKG;PDE4D 13929:[DB04998 DB01071] DB04998|AGRO100 IKBKG DB01071|Mequitazine HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 13930:[DB04998 DB01427] DB04998|AGRO100 IKBKG DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;IKBKG GO:0009615| response to virus IKBKG;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0006954| inflammatory response TNF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TNF GO:0006955| immune response TNF;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;PDE4B GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0007254| JNK cascade TNF;IKBKG GO:0000187| activation of MAPK activity IKBKG;TNF 13931:[DB04998 DB00349] DB04998|AGRO100 IKBKG DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 13932:[DB04998 DB05229] DB04998|AGRO100 IKBKG DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways 13933:[DB04998 DB05488] DB04998|AGRO100 IKBKG DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways 13934:[DB04998 DB01394] DB04998|AGRO100 IKBKG DB01394|Colchicine TUBB1;TUBB;CYP3A4;CYP2B6;CYP2C8;CYP2E1;ABCB4;SLC22A3;ABCB1;ABCC1 common genes common pathways 13935:[DB04998 DB14541] DB04998|AGRO100 IKBKG DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006955| immune response IKBKG;CYP11B1 GO:0006954| inflammatory response ANXA1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0045087| innate immune response ANXA1;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 13936:[DB04998 DB01037] DB04998|AGRO100 IKBKG DB01037|Selegiline MAOB;MAOA;CYP2B6;CYP3A4;CYP2A6;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP2E1;ABCB1 common genes common pathways 13937:[DB04998 DB00927] DB04998|AGRO100 IKBKG DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0006955| immune response HRH2;IKBKG 13938:[DB04998 DB09006] DB04998|AGRO100 IKBKG DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG;PPARA;PPARD GO:0045087| innate immune response IKBKG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;IKBKG;PPARG GO:0006351| transcription, DNA-dependent PPARG;IKBKG;PPARA;PPARD GO:0006915| apoptotic process IKBKG;PPARD 13939:[DB04998 DB01268] DB04998|AGRO100 IKBKG DB01268|Sunitinib PDGFRB;FLT1;KIT;KDR;FLT4;FLT3;CSF1R;PDGFRA;CYP3A5;CYP3A7;CYP3A4;ABCC4;ABCB1;ABCC2;ABCG2 common genes common pathways GO:0000187| activation of MAPK activity KIT;IKBKG GO:0016032| viral reproduction KDR;PDGFRA;IKBKG GO:0006954| inflammatory response CSF1R;KIT;IKBKG GO:0016239| positive regulation of macroautophagy IKBKG;KDR GO:0045087| innate immune response IKBKG;CSF1R 13940:[DB04998 DB00363] DB04998|AGRO100 IKBKG DB00363|Clozapine DRD2;HTR2A;DRD1;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;HRH4;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALY;GSTP1;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2C19;CYP2A6;CYP2C8;FMO3;UGT1A4;CYP2E1;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity DRD4;ADRA2B;IKBKG GO:0006954| inflammatory response HRH4;HRH1;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0009615| response to virus IKBKG;CYP1A1;CHRM2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG 13941:[DB04998 DB09318] DB04998|AGRO100 IKBKG DB09318|Synthetic Conjugated Estrogens, B ESR1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;ESR1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR1 GO:0016579| protein deubiquitination IKBKG;ESR1 13942:[DB04998 DB00928] DB04998|AGRO100 IKBKG DB00928|Azacitidine DNMT1;CDA common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;DNMT1 GO:0006351| transcription, DNA-dependent DNMT1;IKBKG 13943:[DB04998 DB05029] DB04998|AGRO100 IKBKG DB05029|Lancovutide PLA2G4A common genes common pathways 13944:[DB04998 DB00564] DB04998|AGRO100 IKBKG DB00564|Carbamazepine SCN5A;CHRNA4;CHRNB2;NR1I2;CYP3A4;CYP2C8;CYP1A2;CYP2C9;CYP2C19;CYP2B6;CYP3A5;CYP3A7;UGT2B7;UGT1A1;ABCB1;RALBP1;ABCC2 common genes common pathways GO:0006351| transcription, DNA-dependent NR1I2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2 13945:[DB04998 DB00262] DB04998|AGRO100 IKBKG DB00262|Carmustine GSR;CYP1A2 common genes common pathways 13946:[DB04998 DB13520] DB04998|AGRO100 IKBKG DB13520|Metergoline SCN2A common genes common pathways 13947:[DB04998 DB14019] DB04998|AGRO100 IKBKG DB14019|Fosnetupitant CYP3A4 common genes common pathways 13948:[DB04998 DB09059] DB04998|AGRO100 IKBKG DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade AVPR2;IKBKG 13949:[DB04998 DB01454] DB04998|AGRO100 IKBKG DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0016032| viral reproduction HTR2A;IKBKG 13950:[DB04998 DB00204] DB04998|AGRO100 IKBKG DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways 13951:[DB04998 DB05459] DB04998|AGRO100 IKBKG DB05459|Briakinumab IL12B;IL23A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;IL23A GO:0045087| innate immune response IL23A;IKBKG GO:0006954| inflammatory response IL23A;IKBKG GO:0006955| immune response IL23A;IKBKG 13952:[DB04998 DB00813] DB04998|AGRO100 IKBKG DB00813|Fentanyl OPRM1;OPRD1;OPRK1;ABCB1;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1;OPRD1 13953:[DB04998 DB00914] DB04998|AGRO100 IKBKG DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0006351| transcription, DNA-dependent PRKAA1;IKBKG GO:0006355| regulation of transcription, DNA-dependent PRKAA1;IKBKG GO:0000187| activation of MAPK activity IKBKG;PRKAA1 13954:[DB04998 DB00469] DB04998|AGRO100 IKBKG DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13955:[DB04998 DB00620] DB04998|AGRO100 IKBKG DB00620|Triamcinolone NR3C1;CYP3A4;PTGS2;BCHE;SERPINA6 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 13956:[DB04998 DB00454] DB04998|AGRO100 IKBKG DB00454|Meperidine OPRK1;GRIN1;GRIN2B;GRIN2A;GRIN2C;GRIN2D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;OPRM1;SLC6A3;SLC6A2;SLC6A4;CES1;CYP3A4;CYP2C19;CYP2B6;CYP2D6;CYP1A2;ALB;ORM1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 GO:0009615| response to virus IKBKG;CHRM2 GO:0006954| inflammatory response IKBKG;ORM1 GO:0006955| immune response OPRK1;IKBKG 13957:[DB04998 DB00489] DB04998|AGRO100 IKBKG DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 13958:[DB04998 DB01015] DB04998|AGRO100 IKBKG DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1 13959:[DB04998 DB00321] DB04998|AGRO100 IKBKG DB00321|Amitriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;OPRD1;OPRK1;NTRK1;NTRK2;ADRA1A;ADRA1D;ADRA2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCNQ2;KCNA1;KCND2;KCND3;HRH2;HRH4;SIGMAR1;HTR2C;ADRA1B;HTR7;HTR1D;OPRM1;HTR1B;HTR6;KCNQ3;ADRB1;ADRB2;ADRB3;CYP2D6;CYP1A2;CYP2C19;CYP2C9;CYP3A4;CYP3A5;CYP2B6;CYP2C8;CYP2E1;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:1901215| NTRK1;IKBKG GO:0006954| inflammatory response ORM1;IKBKG;HRH1;HRH4 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;NTRK1 GO:0016032| viral reproduction HTR2A;IKBKG GO:0006955| immune response OPRK1;IKBKG;HRH2;OPRD1 GO:0009615| response to virus CHRM2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A GO:0016579| protein deubiquitination ADRB2;IKBKG 13960:[DB04998 DB02261] DB04998|AGRO100 IKBKG DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0006954| inflammatory response PTAFR;IKBKG GO:0006955| immune response PTAFR;IKBKG 13961:[DB04998 DB00248] DB04998|AGRO100 IKBKG DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity DRD4;ADRA2B;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;DRD3;DRD2;IKBKG 13962:[DB04998 DB00209] DB04998|AGRO100 IKBKG DB00209|Trospium CHRM1;CYP2D6 common genes common pathways 13963:[DB04998 DB00730] DB04998|AGRO100 IKBKG DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 13964:[DB04998 DB04978] DB04998|AGRO100 IKBKG DB04978|SP1049C TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 13965:[DB04998 DB00359] DB04998|AGRO100 IKBKG DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes common pathways 13966:[DB04998 DB00761] DB04998|AGRO100 IKBKG DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways 13967:[DB04998 DB01028] DB04998|AGRO100 IKBKG DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;IKBKG GO:1901215| GABRB3;IKBKG;GABRB2 13968:[DB04998 DB11714] DB04998|AGRO100 IKBKG DB11714|Durvalumab CD274;CD80 common genes common pathways GO:0016032| viral reproduction IKBKG;CD80 GO:0006955| immune response IKBKG;CD274 13969:[DB04998 DB14025] DB04998|AGRO100 IKBKG DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways 13970:[DB04998 DB14634] DB04998|AGRO100 IKBKG DB14634|Fluprednidene acetate CYP3A4 common genes common pathways 13971:[DB04998 DB06543] DB04998|AGRO100 IKBKG DB06543|Astaxanthin NFKBIA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKBIA;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;NFKBIA GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;NFKBIA GO:0016032| viral reproduction IKBKG;NFKBIA GO:0050852| T cell receptor signaling pathway IKBKG;NFKBIA GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;NFKBIA GO:0016579| protein deubiquitination NFKBIA;IKBKG GO:0006915| apoptotic process IKBKG;NFKBIA GO:0038095| NFKBIA;IKBKG 13972:[DB04998 DB00154] DB04998|AGRO100 IKBKG DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 13973:[DB04998 DB12278] DB04998|AGRO100 IKBKG DB12278|Propiverine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CACNA1C;ADRA1A;CYP3A4;FMO1;FMO3;CYP2B common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 GO:0006915| apoptotic process IKBKG;ADRA1A 13974:[DB04998 DB08908] DB04998|AGRO100 IKBKG DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0038095| IKBKG;RELA GO:0016579| protein deubiquitination IKBKG;KEAP1 GO:0006351| transcription, DNA-dependent KEAP1;IKBKG;RELA GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade RELA;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;RELA GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;RELA GO:0050852| T cell receptor signaling pathway IKBKG;RELA GO:0006355| regulation of transcription, DNA-dependent RELA;KEAP1;IKBKG GO:0016032| viral reproduction RELA;IKBKG GO:0006954| inflammatory response RELA;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;RELA 13975:[DB04998 DB05104] DB04998|AGRO100 IKBKG DB05104|Asimadoline OPRK1 common genes common pathways GO:0006955| immune response OPRK1;IKBKG 13976:[DB04998 DB09071] DB04998|AGRO100 IKBKG DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways 13977:[DB04998 DB00712] DB04998|AGRO100 IKBKG DB00712|Flurbiprofen PTGS1;PTGS2;CYP2C9;UGT2B7;UGT1A1;UGT1A3;UGT1A9;UGT2B4;ALB;ABCC4;SLC22A6 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13978:[DB04998 DB05706] DB04998|AGRO100 IKBKG DB05706|13-deoxydoxorubicin TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus IKBKG;TOP2A 13979:[DB04998 DB02123] DB04998|AGRO100 IKBKG DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction SLC10A1;IKBKG 13980:[DB04998 DB06335] DB04998|AGRO100 IKBKG DB06335|Saxagliptin DPP4;CYP3A4;CYP3A5;ABCC1;SLCO4C1;SLC22A8 common genes common pathways 13981:[DB04998 DB00900] DB04998|AGRO100 IKBKG DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes common pathways GO:0006955| immune response PNP;IKBKG 13982:[DB04998 DB09076] DB04998|AGRO100 IKBKG DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13983:[DB04998 DB00665] DB04998|AGRO100 IKBKG DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0016579| protein deubiquitination AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent AR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006351| transcription, DNA-dependent AR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AR 13984:[DB04998 DB00977] DB04998|AGRO100 IKBKG DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;NR1I2;IKBKG GO:0016032| viral reproduction SLC10A1;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;IKBKG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG;NR1I2 GO:0016579| protein deubiquitination ESR1;IKBKG 13985:[DB04998 DB00246] DB04998|AGRO100 IKBKG DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG GO:0006954| inflammatory response HRH1;IKBKG GO:0016032| viral reproduction HTR2A;IKBKG GO:0009615| response to virus IKBKG;CHRM2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3 13986:[DB04998 DB00907] DB04998|AGRO100 IKBKG DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 13987:[DB04998 DB00605] DB04998|AGRO100 IKBKG DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARD;IKBKG GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG GO:0006955| immune response PTGDR2;IKBKG GO:0016032| viral reproduction MAPK3;IKBKG GO:0051403| stress-activated MAPK cascade MAPK3;IKBKG GO:0006351| transcription, DNA-dependent MAPK3;PPARD;IKBKG GO:0006974| response to DNA damage stimulus MAPK3;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;MAPK3 GO:0006915| apoptotic process MAPK3;PPARD;IKBKG GO:0000187| activation of MAPK activity IKBKG;MAPK3 GO:0038095| IKBKG;MAPK3 13988:[DB04998 DB05187] DB04998|AGRO100 IKBKG DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0006915| apoptotic process PPARD;IKBKG GO:0045087| innate immune response IKBKG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;IKBKG;PPARG GO:0006351| transcription, DNA-dependent PPARD;PPARA;PPARG;IKBKG GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG;PPARD;PPARA 13989:[DB04998 DB05838] DB04998|AGRO100 IKBKG DB05838|OPC-51803 AVPR2 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;AVPR2 13990:[DB04998 DB01355] DB04998|AGRO100 IKBKG DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1 GO:0000187| activation of MAPK activity IKBKG;CHRNA7 13991:[DB04998 DB00651] DB04998|AGRO100 IKBKG DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0006915| apoptotic process ADORA2A;IKBKG GO:0006954| inflammatory response ADORA1;ADORA2A;IKBKG GO:0050852| T cell receptor signaling pathway PDE4B;IKBKG;PDE4D GO:0006355| regulation of transcription, DNA-dependent ADORA2A;IKBKG 13992:[DB04998 DB06230] DB04998|AGRO100 IKBKG DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0006955| immune response OPRD1;IKBKG;OPRK1 13993:[DB04998 DB11182] DB04998|AGRO100 IKBKG DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways GO:0006351| transcription, DNA-dependent LTF;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;IKBKG GO:0045087| innate immune response IKBKG;LTF GO:0006355| regulation of transcription, DNA-dependent LTF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;LTF GO:0006954| inflammatory response IKBKG;LYZ 13994:[DB04998 DB00457] DB04998|AGRO100 IKBKG DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG GO:0006954| inflammatory response IKBKG;ORM1 GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity IKBKG;ADRA2B 13995:[DB04998 DB09048] DB04998|AGRO100 IKBKG DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0006954| inflammatory response TACR1;IKBKG 13996:[DB04998 DB02527] DB04998|AGRO100 IKBKG DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways 13997:[DB04998 DB09216] DB04998|AGRO100 IKBKG DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 13998:[DB04998 DB00820] DB04998|AGRO100 IKBKG DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways 13999:[DB04998 DB07954] DB04998|AGRO100 IKBKG DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0000187| activation of MAPK activity PDE6G;IKBKG GO:0006355| regulation of transcription, DNA-dependent PDE8A;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;PDE4D 14000:[DB04998 DB11363] DB04998|AGRO100 IKBKG DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;ALK GO:0000187| activation of MAPK activity IKBKG;ALK 14001:[DB04998 DB08889] DB04998|AGRO100 IKBKG DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways GO:0038095| IKBKG;PSMB8;PSMB10;PSMB2;PSMB9;PSMB5;PSMB1 GO:0016579| protein deubiquitination IKBKG;PSMB8;PSMB10;PSMB1;PSMB5;PSMB9;PSMB2 GO:0002223| stimulatory C-type lectin receptor signaling pathway PSMB8;IKBKG;PSMB5;PSMB1;PSMB9;PSMB2;PSMB10 GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;PSMB8;PSMB10;PSMB5;PSMB1;PSMB2;PSMB9 GO:0050852| T cell receptor signaling pathway PSMB8;IKBKG;PSMB5;PSMB1;PSMB2;PSMB9;PSMB10 GO:0016032| viral reproduction PSMB9;PSMB2;PSMB5;PSMB1;PSMB10;PSMB8;IKBKG 14002:[DB04998 DB11605] DB04998|AGRO100 IKBKG DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1H4;PPARA;NR1I2;IKBKG GO:1901215| IKBKG;PPARA GO:0006954| inflammatory response IKBKG;NR1H4 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG;PPARA;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG;NR1H4;PPARA GO:0045087| innate immune response NR1H4;IKBKG 14003:[DB04998 DB06728] DB04998|AGRO100 IKBKG DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways 14004:[DB04998 DB00687] DB04998|AGRO100 IKBKG DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0006915| apoptotic process NR3C1;IKBKG GO:0016579| protein deubiquitination AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C2;AR;NR3C1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006351| transcription, DNA-dependent AR;NR3C1;IKBKG;NR3C2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;AR;IKBKG 14005:[DB04998 DB09301] DB04998|AGRO100 IKBKG DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;HEXB;GDNF;VEGFA GO:0006955| immune response IKBKG;CCL2 GO:0006954| inflammatory response CCL2;IKBKG 14006:[DB04998 DB01137] DB04998|AGRO100 IKBKG DB01137|Levofloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;ABCB1;SLC22A6;SLC22A2;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0006974| response to DNA damage stimulus IKBKG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 14007:[DB04998 DB01544] DB04998|AGRO100 IKBKG DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0006915| apoptotic process IKBKG;TSPO GO:1901215| GABRB3;IKBKG 14008:[DB04998 DB01414] DB04998|AGRO100 IKBKG DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways 14009:[DB04998 DB01192] DB04998|AGRO100 IKBKG DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways GO:0006955| immune response OPRD1;IKBKG 14010:[DB04998 DB04743] DB04998|AGRO100 IKBKG DB04743|Nimesulide PTGS2;PLA2G2E;LTF;CYP3A4 common genes common pathways GO:0045087| innate immune response LTF;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;LTF GO:0006351| transcription, DNA-dependent LTF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;LTF GO:0006954| inflammatory response PLA2G2E;IKBKG;PTGS2 GO:0006355| regulation of transcription, DNA-dependent LTF;IKBKG 14011:[DB04998 DB09477] DB04998|AGRO100 IKBKG DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways GO:0006954| inflammatory response BDKRB1;IKBKG 14012:[DB04998 DB08795] DB04998|AGRO100 IKBKG DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 14013:[DB04998 DB09240] DB04998|AGRO100 IKBKG DB09240|Niludipine CYP3A4 common genes common pathways 14014:[DB04998 DB12023] DB04998|AGRO100 IKBKG DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways GO:0006955| immune response FCGR3A;IKBKG 14015:[DB04998 DB13879] DB04998|AGRO100 IKBKG DB13879|Glecaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 14016:[DB04998 DB00571] DB04998|AGRO100 IKBKG DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0009615| response to virus IKBKG;CYP1A1 GO:0006954| inflammatory response ORM1;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 14017:[DB04998 DB04076] DB04998|AGRO100 IKBKG DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0006955| immune response IKBKG;PNP 14018:[DB04998 DB05971] DB04998|AGRO100 IKBKG DB05971|Archexin AKT1 common genes common pathways GO:1901215| IKBKG;AKT1 GO:0043276| anoikis IKBKG;AKT1 GO:0006954| inflammatory response IKBKG;AKT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AKT1 GO:0006974| response to DNA damage stimulus IKBKG;AKT1 GO:0006915| apoptotic process AKT1;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;AKT1 14019:[DB04998 DB12629] DB04998|AGRO100 IKBKG DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways 14020:[DB04998 DB06240] DB04998|AGRO100 IKBKG DB06240|Tariquidar ABCB1 common genes common pathways 14021:[DB04998 DB00806] DB04998|AGRO100 IKBKG DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0006954| inflammatory response ADORA1;ADORA2A;IKBKG GO:0050852| T cell receptor signaling pathway PDE4B;IKBKG GO:0006355| regulation of transcription, DNA-dependent ADORA2A;IKBKG GO:0006915| apoptotic process IKBKG;ADORA2A 14022:[DB04998 DB01273] DB04998|AGRO100 IKBKG DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 14023:[DB04998 DB07447] DB04998|AGRO100 IKBKG DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways 14024:[DB04998 DB11752] DB04998|AGRO100 IKBKG DB11752|Bryostatin 1 CYP3A4 common genes common pathways 14025:[DB04998 DB00498] DB04998|AGRO100 IKBKG DB00498|Phenindione VKORC1 common genes common pathways 14026:[DB04998 DB14146] DB04998|AGRO100 IKBKG DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1;OPRD1 14027:[DB04998 DB00808] DB04998|AGRO100 IKBKG DB00808|Indapamide SLC12A3;CYP3A4 common genes common pathways 14028:[DB04998 DB00159] DB04998|AGRO100 IKBKG DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0006915| apoptotic process IKBKG;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;IKBKG GO:0045087| innate immune response PPARG;IKBKG GO:0006351| transcription, DNA-dependent PPARA;PPARD;PPARG;IKBKG GO:0006954| inflammatory response TRPV1;IKBKG;PTGS2;PTGS1 GO:0006355| regulation of transcription, DNA-dependent IKBKG;PPARG;FADS1;PPARD;PPARA GO:1901215| IKBKG;PPARA 14029:[DB04998 DB04903] DB04998|AGRO100 IKBKG DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways 14030:[DB04998 DB00727] DB04998|AGRO100 IKBKG DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways 14031:[DB04998 DB13014] DB04998|AGRO100 IKBKG DB13014|Hypericin GSTA1;GSTP1;ALB common genes common pathways 14032:[DB04998 DB00951] DB04998|AGRO100 IKBKG DB00951|Isoniazid katG;CYP2C8;CYP1A2;CYP3A4;CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2D6;CYP2C19;NAT2;CYP2A6;CYP2C8;ALB common genes common pathways 14033:[DB04998 DB00988] DB04998|AGRO100 IKBKG DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;POU5F1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter POU5F1;IKBKG;DRD2;DRD3 GO:0006355| regulation of transcription, DNA-dependent IKBKG;POU5F1 GO:0000187| activation of MAPK activity SOD1;DRD4;IKBKG 14034:[DB04998 DB12742] DB04998|AGRO100 IKBKG DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;KIT GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;MET GO:0006974| response to DNA damage stimulus RAD51;IKBKG GO:0006954| inflammatory response KIT;IKBKG GO:0016032| viral reproduction IKBKG;PDGFRA 14035:[DB04998 DB00317] DB04998|AGRO100 IKBKG DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0006954| inflammatory response IKBKG;ORM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IKBKG GO:0009615| response to virus CYP1A1;IKBKG 14036:[DB04998 DB00433] DB04998|AGRO100 IKBKG DB00433|Prochlorperazine DRD2;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 14037:[DB04998 DB01184] DB04998|AGRO100 IKBKG DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 14038:[DB04998 DB11915] DB04998|AGRO100 IKBKG DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways 14039:[DB04998 DB01579] DB04998|AGRO100 IKBKG DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 14040:[DB04998 DB05964] DB04998|AGRO100 IKBKG DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG 14041:[DB04998 DB06663] DB04998|AGRO100 IKBKG DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways 14042:[DB04998 DB00082] DB04998|AGRO100 IKBKG DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;GHR 14043:[DB04998 DB00870] DB04998|AGRO100 IKBKG DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 14044:[DB04998 DB06196] DB04998|AGRO100 IKBKG DB06196|Icatibant BDKRB2;ANPEP common genes common pathways GO:0016032| viral reproduction ANPEP;IKBKG GO:0006954| inflammatory response BDKRB2;IKBKG 14045:[DB04998 DB01442] DB04998|AGRO100 IKBKG DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG 14046:[DB04998 DB00899] DB04998|AGRO100 IKBKG DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response OPRK1;IKBKG;OPRD1 14047:[DB04998 DB00218] DB04998|AGRO100 IKBKG DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A 14048:[DB04998 DB01103] DB04998|AGRO100 IKBKG DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways 14049:[DB04998 DB13165] DB04998|AGRO100 IKBKG DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade ROCK2;ROCK1;IKBKG GO:0006915| apoptotic process ROCK1;IKBKG 14050:[DB04998 DB00686] DB04998|AGRO100 IKBKG DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;FGF2;FGF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF4;IKBKG;FGF2;FGF1 14051:[DB04998 DB06203] DB04998|AGRO100 IKBKG DB06203|Alogliptin DPP4;CYP3A4;CYP2D6 common genes common pathways 14052:[DB04998 DB00245] DB04998|AGRO100 IKBKG DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 14053:[DB04998 DB14070] DB04998|AGRO100 IKBKG DB14070|HM-30181 ABCB1 common genes common pathways 14054:[DB04998 DB03477] DB04998|AGRO100 IKBKG DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2 14055:[DB04998 DB00091] DB04998|AGRO100 IKBKG DB00091|Ciclosporin CAMLG;PPP3R2;PPIA;PPIF;CYP3A7;CYP3A5;CYP3A4;CYP2C19;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCC3;ABCB11;ABCC1;SLCO1A2;SLC10A2;SLC10A1;SLC22A6;ABCC10;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006915| apoptotic process PPIF;IKBKG GO:0016032| viral reproduction IKBKG;SLC10A1;CAMLG;PPIA 14056:[DB04998 DB11156] DB04998|AGRO100 IKBKG DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways 14057:[DB04998 DB08935] DB04998|AGRO100 IKBKG DB08935|Obinutuzumab MS4A1 common genes common pathways 14058:[DB04998 DB05131] DB04998|AGRO100 IKBKG DB05131|TTP889 F9 common genes common pathways 14059:[DB04998 DB09546] DB04998|AGRO100 IKBKG DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways 14060:[DB04998 DB08964] DB04998|AGRO100 IKBKG DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways 14061:[DB04998 DB08496] DB04998|AGRO100 IKBKG DB08496|(R)-warfarin CYP2C8;CYP2C9;CYP2C18;CYP2C19;CYP1A2;CYP1A1;CYP3A4;ALB common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 14062:[DB04998 DB08879] DB04998|AGRO100 IKBKG DB08879|Belimumab TNFSF13B common genes common pathways GO:0006955| immune response TNFSF13B;IKBKG 14063:[DB04998 DB05804] DB04998|AGRO100 IKBKG DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0006954| inflammatory response PTGS2;IKBKG 14064:[DB04998 DB00970] DB04998|AGRO100 IKBKG DB00970|Dactinomycin TOP2A;TOP2B;SLC22A5;ABCB1;ABCC6;ABCC1;ABCG2 common genes common pathways GO:0006974| response to DNA damage stimulus TOP2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG 14065:[DB04998 DB13074] DB04998|AGRO100 IKBKG DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways 14066:[DB04998 DB11133] DB04998|AGRO100 IKBKG DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0006351| transcription, DNA-dependent PPARA;PPARG;SREBF1;IKBKG GO:0045087| innate immune response PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;SREBF1;IKBKG GO:1901215| PPARA;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;SREBF1;IKBKG;PPARA GO:0006954| inflammatory response IKBKG;ALOX5;PTGS2 14067:[DB04998 DB01325] DB04998|AGRO100 IKBKG DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways 14068:[DB04998 DB01353] DB04998|AGRO100 IKBKG DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG 14069:[DB04998 DB00230] DB04998|AGRO100 IKBKG DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways 14070:[DB04998 DB12301] DB04998|AGRO100 IKBKG DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways 14071:[DB04998 DB00758] DB04998|AGRO100 IKBKG DB00758|Clopidogrel P2RY12;CYP3A4;CYP2B6;CYP3A5;CYP2C19;CYP2C9;CYP1A2;CYP2C8;CES1;ABCB1;SLC22A1;SLC22A2 common genes common pathways 14072:[DB04998 DB13174] DB04998|AGRO100 IKBKG DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1H3;NR1H2 GO:0006954| inflammatory response IKBKG;ALOX5 GO:0006351| transcription, DNA-dependent IKBKG;NR1H3;NR1H2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H2;NR1H3;IKBKG 14073:[DB04998 DB05099] DB04998|AGRO100 IKBKG DB05099|Ancrod FGA common genes common pathways GO:0045087| innate immune response IKBKG;FGA 14074:[DB04998 DB11738] DB04998|AGRO100 IKBKG DB11738|Rilmenidine ADRA2A common genes common pathways 14075:[DB04998 DB00588] DB04998|AGRO100 IKBKG DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C2;PGR;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;PGR;NR3C2;IKBKG GO:0006915| apoptotic process NR3C1;IKBKG 14076:[DB04998 DB08828] DB04998|AGRO100 IKBKG DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter SMO;IKBKG 14077:[DB04998 DB07449] DB04998|AGRO100 IKBKG DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;PADI4 GO:0006351| transcription, DNA-dependent PADI4;IKBKG GO:0045087| innate immune response IKBKG;PADI4 14078:[DB04998 DB00388] DB04998|AGRO100 IKBKG DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A 14079:[DB04998 DB00819] DB04998|AGRO100 IKBKG DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways 14080:[DB04998 DB00284] DB04998|AGRO100 IKBKG DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 14081:[DB04998 DB01067] DB04998|AGRO100 IKBKG DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARG GO:0045087| innate immune response IKBKG;PPARG GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG 14082:[DB04998 DB01401] DB04998|AGRO100 IKBKG DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG 14083:[DB04998 DB01159] DB04998|AGRO100 IKBKG DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ATP2C1 GO:1901215| GABRB3;GABRB2;IKBKG 14084:[DB04998 DB05889] DB04998|AGRO100 IKBKG DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways 14085:[DB04998 DB01013] DB04998|AGRO100 IKBKG DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 14086:[DB04998 DB04868] DB04998|AGRO100 IKBKG DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;KIT GO:0006915| apoptotic process IKBKG;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ABL1 GO:0045087| innate immune response ABL1;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;IKBKG GO:0006954| inflammatory response KIT;IKBKG 14087:[DB04998 DB06235] DB04998|AGRO100 IKBKG DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways 14088:[DB04998 DB14066] DB04998|AGRO100 IKBKG DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways 14089:[DB04998 DB00703] DB04998|AGRO100 IKBKG DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways 14090:[DB04998 DB00337] DB04998|AGRO100 IKBKG DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;IKBKG GO:0043276| anoikis IKBKG;MTOR 14091:[DB04998 DB01069] DB04998|AGRO100 IKBKG DB01069|Promethazine HRH1;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;HTR2A;CALM1;HRH2;CYP2D6;CYP2B6;CYP2C9;ABCB1 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 GO:0006955| immune response IKBKG;HRH2 GO:0016032| viral reproduction HTR2A;IKBKG GO:0009615| response to virus CHRM2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A GO:0038095| IKBKG;CALM1 14092:[DB04998 DB00203] DB04998|AGRO100 IKBKG DB00203|Sildenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2D6;CYP1A1;CYP2E1;ABCC4;ABCC5;ABCC10;SLCO1B1;ABCB1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG GO:0000187| activation of MAPK activity PDE6H;IKBKG;PDE6G 14093:[DB04998 DB06470] DB04998|AGRO100 IKBKG DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways 14094:[DB04998 DB01340] DB04998|AGRO100 IKBKG DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways 14095:[DB04998 DB01042] DB04998|AGRO100 IKBKG DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways 14096:[DB04998 DB05297] DB04998|AGRO100 IKBKG DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0006915| apoptotic process IKBKG;BCL2 GO:0006974| response to DNA damage stimulus BCL2;IKBKG 14097:[DB04998 DB00009] DB04998|AGRO100 IKBKG DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0045087| innate immune response FGA;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;IKBKG 14098:[DB04998 DB07285] DB04998|AGRO100 IKBKG DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 14099:[DB04998 DB01628] DB04998|AGRO100 IKBKG DB01628|Etoricoxib PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2 14100:[DB04998 DB01001] DB04998|AGRO100 IKBKG DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG 14101:[DB04998 DB01002] DB04998|AGRO100 IKBKG DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways 14102:[DB04998 DB04842] DB04998|AGRO100 IKBKG DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 14103:[DB04998 DB01392] DB04998|AGRO100 IKBKG DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;IKBKG;DRD2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0016032| viral reproduction IKBKG;HTR2A GO:0000187| activation of MAPK activity IKBKG;ADRA2B 14104:[DB04998 DB01809] DB04998|AGRO100 IKBKG DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0045087| innate immune response IKBKG;HCK GO:0016032| viral reproduction HCK;IKBKG GO:0006954| inflammatory response IKBKG;HCK 14105:[DB04998 DB00833] DB04998|AGRO100 IKBKG DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways 14106:[DB04998 DB00591] DB04998|AGRO100 IKBKG DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0006954| inflammatory response ANXA1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0045087| innate immune response ANXA1;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0006915| apoptotic process NR3C1;IKBKG 14107:[DB04998 DB01549] DB04998|AGRO100 IKBKG DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 14108:[DB04998 DB06788] DB04998|AGRO100 IKBKG DB06788|Histrelin GNRHR common genes common pathways 14109:[DB04998 DB01142] DB04998|AGRO100 IKBKG DB01142|Doxepin HRH1;HRH2;SLC6A2;SLC6A4;HTR2A;HTR2B;HTR2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR1A;ADRA2A;ADRA2B;ADRA2C;DRD2;HTR6;HRH4;KCNH2;CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;ORM1;ABCB1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B GO:0006915| apoptotic process ADRA1A;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 GO:0009615| response to virus CHRM2;IKBKG GO:0006954| inflammatory response ORM1;IKBKG;HRH1;HRH4 GO:0016032| viral reproduction IKBKG;HTR2A GO:0006955| immune response HRH2;IKBKG 14110:[DB04998 DB05271] DB04998|AGRO100 IKBKG DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 GO:0000187| activation of MAPK activity IKBKG;ADRA2B;DRD4 14111:[DB04998 DB00904] DB04998|AGRO100 IKBKG DB00904|Ondansetron HTR3A;HTR4;OPRM1;HTR1A;HTR1B;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP2C9;CYP2E1 common genes common pathways 14112:[DB04998 DB12483] DB04998|AGRO100 IKBKG DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways GO:0038095| IKBKG;PIK3CA GO:0045087| innate immune response IKBKG;PIK3CD;PIK3CA GO:0050852| T cell receptor signaling pathway PIK3CD;IKBKG;PIK3CA GO:0043276| anoikis IKBKG;PIK3CA GO:0006954| inflammatory response IKBKG;PIK3CD;PIK3CA 14113:[DB04998 DB11693] DB04998|AGRO100 IKBKG DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways GO:0038095| IKBKG;PPP3R1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPP3R1;IKBKG 14114:[DB04998 DB05152] DB04998|AGRO100 IKBKG DB05152|NGX267 CHRM1 common genes common pathways 14115:[DB04998 DB11529] DB04998|AGRO100 IKBKG DB11529|Melengestrol CYP3A4 common genes common pathways 14116:[DB04998 DB01931] DB04998|AGRO100 IKBKG DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 14117:[DB04998 DB02659] DB04998|AGRO100 IKBKG DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESRRG;IKBKG;NR1H4 GO:0016032| viral reproduction IKBKG;SLC10A1 GO:0006954| inflammatory response IKBKG;NR1H4 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;PLA2G1B GO:0006351| transcription, DNA-dependent ESRRG;IKBKG;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PLA2G1B;ESRRG;NR1H4 GO:0045087| innate immune response IKBKG;NR1H4 GO:0000187| activation of MAPK activity IKBKG;PLA2G1B 14118:[DB04998 DB01189] DB04998|AGRO100 IKBKG DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;IKBKG GO:1901215| IKBKG;GABRB2;GABRB3 14119:[DB04998 DB05110] DB04998|AGRO100 IKBKG DB05110|VIR201 IFNG common genes common pathways GO:0006955| immune response IFNG;IKBKG GO:0009615| response to virus IFNG;IKBKG GO:0006915| apoptotic process IKBKG;IFNG 14120:[DB04998 DB00432] DB04998|AGRO100 IKBKG DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways 14121:[DB04998 DB12116] DB04998|AGRO100 IKBKG DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0006351| transcription, DNA-dependent DNMT1;AHR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AHR GO:0006355| regulation of transcription, DNA-dependent AHR;IKBKG;DNMT1 GO:0006915| apoptotic process AHR;IKBKG 14122:[DB04998 DB00307] DB04998|AGRO100 IKBKG DB00307|Bexarotene RXRA;RXRB;RXRG;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRG;IKBKG;RXRA;RXRB GO:0006351| transcription, DNA-dependent RXRG;IKBKG;RXRA;RXRB GO:0016032| viral reproduction RXRA;IKBKG GO:0006355| regulation of transcription, DNA-dependent RXRB;RXRA;IKBKG;RXRG 14123:[DB04998 DB02309] DB04998|AGRO100 IKBKG DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 14124:[DB04998 DB00731] DB04998|AGRO100 IKBKG DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARG GO:0045087| innate immune response PPARG;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG GO:0006954| inflammatory response PTGS1;IKBKG;ORM1 14125:[DB04998 DB04932] DB04998|AGRO100 IKBKG DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0007254| JNK cascade ADORA2B;IKBKG GO:0000187| activation of MAPK activity IKBKG;ADORA2B GO:0006915| apoptotic process IKBKG;ADORA2A GO:0006954| inflammatory response IKBKG;ADORA2A;ADORA1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;IKBKG 14126:[DB04998 DB00334] DB04998|AGRO100 IKBKG DB00334|Olanzapine HTR2A;DRD2;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR5A;DRD1;DRD5;HRH2;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;ADRB1;ADRB2;ADRB3;CYP1A2;CYP2D6;FMO3;CYP2C19;CYP3A4;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity DRD4;ADRA2B;IKBKG GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0009615| response to virus CHRM2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3;ADRB2 GO:1901215| GABRB2;IKBKG;GABRB3 GO:0006955| immune response IKBKG;HRH2 GO:0016032| viral reproduction IKBKG;HTR2A GO:0006954| inflammatory response HRH1;HRH4;IKBKG;ORM1 14127:[DB04998 DB00783] DB04998|AGRO100 IKBKG DB00783|Estradiol ESR1;ESR2;NR1I2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP3A4;CYP1A2;CYP3A5;CYP3A7;UGT1A1;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR2;IKBKG;ESRRG;NR1I2;NCOA2;ESR1 GO:0006954| inflammatory response IKBKG;GPER1 GO:0016032| viral reproduction BECN1;IKBKG GO:0006351| transcription, DNA-dependent ESR1;NCOA2;NR1I2;ESRRG;IKBKG;ESR2 GO:0045087| innate immune response GPER1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ESR2;ESRRG;NR1I2;NCOA2;GPER1;ESR1 GO:0009615| response to virus IKBKG;CYP1A1 GO:0006915| apoptotic process GPER1;IKBKG;BECN1 GO:0016579| protein deubiquitination ESR1;BECN1;IKBKG 14128:[DB04998 DB14543] DB04998|AGRO100 IKBKG DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006954| inflammatory response ANXA1;IKBKG GO:0006955| immune response CYP11B1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0045087| innate immune response ANXA1;IKBKG GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0006915| apoptotic process NR3C1;IKBKG 14129:[DB04998 DB01221] DB04998|AGRO100 IKBKG DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;NOS1 GO:0009615| response to virus CHRM2;IKBKG GO:0006955| immune response OPRD1;OPRK1;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0006954| inflammatory response PTGS1;TACR1;IKBKG GO:0000187| activation of MAPK activity IKBKG;CHRNA7 14130:[DB04998 DB05541] DB04998|AGRO100 IKBKG DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0006954| inflammatory response SCN9A;IKBKG 14131:[DB04998 DB01164] DB04998|AGRO100 IKBKG DB01164|Calcium Chloride S100A13 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100A13;IKBKG 14132:[DB04998 DB06678] DB04998|AGRO100 IKBKG DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0006954| inflammatory response HRH1;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG 14133:[DB04998 DB09283] DB04998|AGRO100 IKBKG DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0006915| apoptotic process PDE1B;IKBKG GO:0050852| T cell receptor signaling pathway IKBKG;PDE4B;PDE4D GO:0006355| regulation of transcription, DNA-dependent PDE8A;IKBKG 14134:[DB04998 DB00740] DB04998|AGRO100 IKBKG DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 14135:[DB04998 DB09317] DB04998|AGRO100 IKBKG DB09317|Synthetic Conjugated Estrogens, A ESR1;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR1 GO:0016579| protein deubiquitination IKBKG;ESR1 14136:[DB04998 DB14067] DB04998|AGRO100 IKBKG DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways 14137:[DB04998 DB00297] DB04998|AGRO100 IKBKG DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways 14138:[DB04998 DB11994] DB04998|AGRO100 IKBKG DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;IKBKG;NR1H2 GO:0006351| transcription, DNA-dependent IKBKG;NR1H3;NR1H2 GO:0006954| inflammatory response IKBKG;ALOX5 GO:0006355| regulation of transcription, DNA-dependent NR1H2;IKBKG;NR1H3 14139:[DB04998 DB04841] DB04998|AGRO100 IKBKG DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0006954| inflammatory response IKBKG;HRH1 GO:0009615| response to virus CYP1A1;IKBKG GO:0038095| CALM1;IKBKG 14140:[DB04998 DB05903] DB04998|AGRO100 IKBKG DB05903|KOS-1584 CYP3A4 common genes common pathways 14141:[DB04998 DB00491] DB04998|AGRO100 IKBKG DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 14142:[DB04998 DB09008] DB04998|AGRO100 IKBKG DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways 14143:[DB04998 DB00853] DB04998|AGRO100 IKBKG DB00853|Temozolomide CYP3A4 common genes common pathways 14144:[DB04998 DB01319] DB04998|AGRO100 IKBKG DB01319|Fosamprenavir pol;CYP3A4 common genes common pathways 14145:[DB04998 DB00335] DB04998|AGRO100 IKBKG DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG GO:0016579| protein deubiquitination ADRB2;IKBKG 14146:[DB04998 DB14068] DB04998|AGRO100 IKBKG DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways 14147:[DB04998 DB01285] DB04998|AGRO100 IKBKG DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0006954| inflammatory response CRH;IKBKG 14148:[DB04998 DB08896] DB04998|AGRO100 IKBKG DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0050852| T cell receptor signaling pathway BRAF;IKBKG GO:1901215| NTRK1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ABL1;IKBKG;MAPK11;FGFR1 GO:0016239| positive regulation of macroautophagy KDR;IKBKG GO:0016032| viral reproduction EPHA2;PDGFRA;KDR;IKBKG GO:0006954| inflammatory response IKBKG;KIT GO:0051092| positive regulation of NF-kappaB transcription factor activity NTRK1;IKBKG GO:0006351| transcription, DNA-dependent MAPK11;FGFR1;IKBKG GO:0002223| stimulatory C-type lectin receptor signaling pathway IKBKG;RAF1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;IKBKG GO:0006974| response to DNA damage stimulus IKBKG;ABL1 GO:0045087| innate immune response FRK;IKBKG;ABL1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;RAF1;FGFR2 GO:0006915| apoptotic process IKBKG;ABL1;EPHA2;FGFR2;RAF1 GO:0000187| activation of MAPK activity IKBKG;MAPK11;KIT 14149:[DB04998 DB00015] DB04998|AGRO100 IKBKG DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0045087| innate immune response IKBKG;FGA GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;IKBKG 14150:[DB04998 DB00752] DB04998|AGRO100 IKBKG DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways 14151:[DB04998 DB09013] DB04998|AGRO100 IKBKG DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 14152:[DB04998 DB00277] DB04998|AGRO100 IKBKG DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0000187| activation of MAPK activity ADORA2B;IKBKG GO:0006915| apoptotic process PARP1;IKBKG;ADORA2A GO:0007254| JNK cascade ADORA2B;IKBKG GO:0006974| response to DNA damage stimulus PARP1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;PARP1;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;CPNE1;PARP1;HDAC2 GO:0006954| inflammatory response IKBKG;ADORA1;ADORA2A GO:0050852| T cell receptor signaling pathway IKBKG;PDE4B GO:0006355| regulation of transcription, DNA-dependent CPNE1;IKBKG;ADORA2A;HDAC2;PARP1 14153:[DB04998 DB09302] DB04998|AGRO100 IKBKG DB09302|Alirocumab PCSK9 common genes common pathways GO:0006915| apoptotic process PCSK9;IKBKG 14154:[DB04998 DB12789] DB04998|AGRO100 IKBKG DB12789|Dinoprost PTGDR2 common genes common pathways GO:0006955| immune response IKBKG;PTGDR2 14155:[DB04998 DB01244] DB04998|AGRO100 IKBKG DB01244|Bepridil CACNA1A;CACNA1H;CACNA2D2;ATP1A1;KCNQ1;TNNC1;CALM1;PDE1B;PDE1A;KCNH2;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0038095| CALM1;IKBKG GO:0006915| apoptotic process PDE1B;IKBKG 14156:[DB04998 DB01175] DB04998|AGRO100 IKBKG DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006915| apoptotic process IKBKG;ADRA1A GO:0006954| inflammatory response IKBKG;HRH1 14157:[DB04998 DB00295] DB04998|AGRO100 IKBKG DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes common pathways GO:0035666| TRIF-dependent toll-like receptor signaling pathway IKBKG;LY96 GO:0007249| I-kappaB kinase/NF-kappaB cascade LY96;IKBKG GO:0002756| MyD88-independent toll-like receptor signaling pathway LY96;IKBKG GO:0045087| innate immune response IKBKG;LY96 GO:0006954| inflammatory response LY96;IKBKG GO:0006955| immune response OPRK1;IKBKG;OPRD1 14158:[DB04998 DB01393] DB04998|AGRO100 IKBKG DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0016032| viral reproduction IKBKG;RXRA GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;RXRA;NR1I2;RXRB;PPARG;RXRG;IKBKG GO:1901215| IKBKG;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;NR1I2;RXRA;PPARG;IKBKG;RXRG;PPARA GO:0009615| response to virus IKBKG;CYP1A1 GO:0045087| innate immune response PPARG;IKBKG GO:0006351| transcription, DNA-dependent PPARA;PPARD;RXRB;NR1I2;RXRA;PPARG;IKBKG;RXRG GO:0006915| apoptotic process IKBKG;PPARD 14159:[DB04998 DB00447] DB04998|AGRO100 IKBKG DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways 14160:[DB04998 DB00492] DB04998|AGRO100 IKBKG DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways 14161:[DB04998 DB00986] DB04998|AGRO100 IKBKG DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 14162:[DB04998 DB05443] DB04998|AGRO100 IKBKG DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0006955| immune response OPRK1;IKBKG 14163:[DB04998 DB05098] DB04998|AGRO100 IKBKG DB05098|Leptin LEPR common genes common pathways 14164:[DB04998 DB00563] DB04998|AGRO100 IKBKG DB00563|Methotrexate DHFR;DHFR;AOX1;MTHFR;PGD;FPGS;TYMS;ATIC;GGH;CYP3A4;ALB;ABCC3;ABCC4;ABCC1;SLC22A6;ABCC10;SLC22A8;ABCC2;ABCB1;SLCO1A2;SLC16A1;ABCC11;SLCO1B3;SLC22A11;SLCO1C1;SLCO3A1;ABCG2;SLC22A7;SLC46A1;SLCO1B1;SLCO4C1;SLC19A1;FOLR1 common genes common pathways 14165:[DB04998 DB00217] DB04998|AGRO100 IKBKG DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 GO:0016579| protein deubiquitination ADRB2;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG 14166:[DB04998 DB09101] DB04998|AGRO100 IKBKG DB09101|Elvitegravir pol;CYP3A4 common genes common pathways 14167:[DB04998 DB09344] DB04998|AGRO100 IKBKG DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways 14168:[DB04998 DB01281] DB04998|AGRO100 IKBKG DB01281|Abatacept CD80;CD86 common genes common pathways GO:0016032| viral reproduction IKBKG;CD86;CD80 GO:0006955| immune response IKBKG;CD86 14169:[DB04998 DB00709] DB04998|AGRO100 IKBKG DB00709|Lamivudine pol;DCK;CMPK1;PGK1;NME1;NME2;PCYT1A;PCYT2;NT5C;ALB;ABCC1;SLC22A6;ABCG2;SLC22A1;SLC22A2;SLC22A3;ABCB1;ABCC4;ABCC3;ABCC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NME2 GO:0006351| transcription, DNA-dependent NME2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;NME2 14170:[DB04998 DB01090] DB04998|AGRO100 IKBKG DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 14171:[DB04998 DB00361] DB04998|AGRO100 IKBKG DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways 14172:[DB04998 DB12140] DB04998|AGRO100 IKBKG DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway TNF;IKBKG GO:0000187| activation of MAPK activity IKBKG;IL1B;TNF GO:0006915| apoptotic process IKBKG;IL1B GO:0007254| JNK cascade IKBKG;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;IL1B;IKBKG;IL6 GO:0009615| response to virus TNF;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IL1B;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;IKBKG;IL6;TNF GO:0006954| inflammatory response IL6;IL1B;IKBKG;TNF GO:0006955| immune response IL6;IKBKG;IL1B;TNF 14173:[DB04998 DB00495] DB04998|AGRO100 IKBKG DB00495|Zidovudine pol;TERT;CYP2A6;CYP2C8;CYP2C9;CYP3A4;TK1;UGT2B7;UGT1A1;ALB;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLC28A1;SLC29A2;ABCB1;ABCC4;ABCC5;ABCG2 common genes common pathways 14174:[DB04998 DB09262] DB04998|AGRO100 IKBKG DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 GO:0006954| inflammatory response ORM1;IKBKG 14175:[DB04998 DB01088] DB04998|AGRO100 IKBKG DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0050852| T cell receptor signaling pathway PDE4D;IKBKG;PDE4B GO:0006955| immune response IKBKG;PTGDR2 14176:[DB04998 DB05294] DB04998|AGRO100 IKBKG DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;EGFR;IKBKG GO:0045087| innate immune response PTK6;IKBKG GO:0006954| inflammatory response ORM1;IKBKG 14177:[DB04998 DB04845] DB04998|AGRO100 IKBKG DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways 14178:[DB04998 DB02852] DB04998|AGRO100 IKBKG DB02852|Domoic Acid GRIK2 common genes common pathways 14179:[DB04998 DB06413] DB04998|AGRO100 IKBKG DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways 14180:[DB04998 DB00544] DB04998|AGRO100 IKBKG DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways 14181:[DB04998 DB00542] DB04998|AGRO100 IKBKG DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways 14182:[DB04998 DB00742] DB04998|AGRO100 IKBKG DB00742|Mannitol ABCB1 common genes common pathways 14183:[DB04998 DB12391] DB04998|AGRO100 IKBKG DB12391|Sagopilone CYP3A4 common genes common pathways 14184:[DB04998 DB08870] DB04998|AGRO100 IKBKG DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways GO:0006955| immune response IKBKG;TNFRSF8 GO:0006954| inflammatory response IKBKG;TNFRSF8 14185:[DB04998 DB01785] DB04998|AGRO100 IKBKG DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0016032| viral reproduction IKBKG;FDPS 14186:[DB04998 DB03683] DB04998|AGRO100 IKBKG DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 14187:[DB04998 DB08873] DB04998|AGRO100 IKBKG DB08873|Boceprevir CYP3A4;CYP3A5;ABCB1 common genes common pathways 14188:[DB04998 DB01413] DB04998|AGRO100 IKBKG DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 14189:[DB04998 DB09212] DB04998|AGRO100 IKBKG DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 14190:[DB04998 DB09119] DB04998|AGRO100 IKBKG DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways 14191:[DB04998 DB03929] DB04998|AGRO100 IKBKG DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 14192:[DB04998 DB00201] DB04998|AGRO100 IKBKG DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes common pathways GO:0038095| IKBKG;PIK3CA;PIK3CB GO:0006915| apoptotic process PDE1B;ATM;ADORA2A;IKBKG;ITPR1 GO:0000187| activation of MAPK activity PIK3CB;IKBKG GO:0006954| inflammatory response IKBKG;PIK3CD;ADORA2A;ADORA1;PIK3CA;PIK3CB GO:0043276| anoikis IKBKG;PIK3CA GO:0006355| regulation of transcription, DNA-dependent ADORA2A;PDE8A;IKBKG GO:0050852| T cell receptor signaling pathway PIK3CD;PDE4B;IKBKG;PDE4D;PIK3CB;PIK3CA GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PRKDC GO:0045087| innate immune response PIK3CD;IKBKG;PRKDC;PIK3CB;PIK3CA GO:0006974| response to DNA damage stimulus ATM;IKBKG;PRKDC 14193:[DB04998 DB00972] DB04998|AGRO100 IKBKG DB00972|Azelastine HRH1;CYP1A2;CYP3A4;CYP2C19;CYP1A1;CYP3A5;CYP2C9;CYP2C8;CYP2D6;CYP2A6;CYP2B6;CYP2E1;ABCB1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG GO:0006954| inflammatory response HRH1;IKBKG 14194:[DB04998 DB12455] DB04998|AGRO100 IKBKG DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways 14195:[DB04998 DB00774] DB04998|AGRO100 IKBKG DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways 14196:[DB04998 DB00402] DB04998|AGRO100 IKBKG DB00402|Eszopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0006915| apoptotic process TSPO;IKBKG GO:0006954| inflammatory response IKBKG;PTGS1 GO:1901215| GABRB3;IKBKG;GABRB2 14197:[DB04998 DB01567] DB04998|AGRO100 IKBKG DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG 14198:[DB04998 DB00480] DB04998|AGRO100 IKBKG DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways GO:0006955| immune response IKBKG;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IKBKG GO:0006954| inflammatory response PTGS2;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IKBKG 14199:[DB04998 DB00771] DB04998|AGRO100 IKBKG DB00771|Clidinium CHRM1 common genes common pathways 14200:[DB04998 DB00700] DB04998|AGRO100 IKBKG DB00700|Eplerenone NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP11B2 common genes common pathways GO:0006351| transcription, DNA-dependent IKBKG;NR3C2 GO:0006355| regulation of transcription, DNA-dependent NR3C2;IKBKG 14201:[DB04998 DB00107] DB04998|AGRO100 IKBKG DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways 14202:[DB04998 DB09214] DB04998|AGRO100 IKBKG DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 14203:[DB04998 DB00659] DB04998|AGRO100 IKBKG DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 GO:1901215| GABRB2;IKBKG;GABRB3 14204:[DB04998 DB01609] DB04998|AGRO100 IKBKG DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways 14205:[DB04998 DB09043] DB04998|AGRO100 IKBKG DB09043|Albiglutide GLP1R common genes common pathways 14206:[DB04998 DB00412] DB04998|AGRO100 IKBKG DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0006915| apoptotic process PPARD;IKBKG GO:1901215| PPARA;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRB;RXRA;IKBKG;RXRG;PPARA;PPARD GO:0006954| inflammatory response IKBKG;PTGS1 GO:0016032| viral reproduction IKBKG;RXRA GO:0006351| transcription, DNA-dependent PPARG;RXRA;RXRB;RXRG;IKBKG;PPARD;PPARA GO:0045087| innate immune response PPARG;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRB;RXRA;IKBKG;RXRG;PPARA 14207:[DB04998 DB01608] DB04998|AGRO100 IKBKG DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AR GO:0006351| transcription, DNA-dependent AR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent AR;IKBKG GO:0016579| protein deubiquitination AR;IKBKG 14208:[DB04998 DB06719] DB04998|AGRO100 IKBKG DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways 14209:[DB04998 DB14487] DB04998|AGRO100 IKBKG DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0016579| protein deubiquitination IKBKG;TP53;MDM2;BRCC3;ESR1 GO:0000187| activation of MAPK activity IKBKG;TP73;APP;SOD1;C5 GO:0006915| apoptotic process PARP1;S100A9;GSN;S100A8;MT3;SIVA1;APLP1;TP53;APP;CLU;IKBKG;PDCD6;TP73 GO:0038095| IGLV3-21;IGKV1-17;IKBKG GO:0045087| innate immune response FGA;FCN3;CFH;CFB;JCHAIN;IKBKG;C1QB;C8B;C1R;APP;CLU;IGHM;S100A7;KRT16;C4B;C8G;C4BPA;PGLYRP2;C8A;S100A9;APCS;C4BPB;F12;APOL1;S100A8;C1QC;C3;CFI;IGHA1;C1S;C5 GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;PDIA3 GO:0006974| response to DNA damage stimulus MGMT;PARP1;BRCC3;MPG;TP53;IKBKG;TP73 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TP73;HDAC1;HDAC4;APP;TP53;ESR1;PARP1 GO:0009615| response to virus IKBKG;ENO1;CLU GO:0051403| stress-activated MAPK cascade AGT;IKBKG GO:0006351| transcription, DNA-dependent HDAC8;PARP1;ESR1;TP73;ENO1;IKBKG;TP53;HDAC1;EEF1A1;HDAC4 GO:0051092| positive regulation of NF-kappaB transcription factor activity CLU;APP;IKBKG;S100A8;S100A9;INS;AGT GO:0006954| inflammatory response C3;KLKB1;C5;S100A9;S100A8;C4B;KRT16;HDAC4;BDKRB1;IKBKG;KNG1;SERPINA3 GO:0006955| immune response C1R;C8B;IKBKG;IGKV1-17;JCHAIN;IGHA1;C3;C1QC;VTN;IGLV3-21;C8A;IL3 GO:0016032| viral reproduction SIVA1;IKBKG;TP73;CFH;IDE;HDAC1;APOA2;TP53;MDM2 GO:1901215| MT3;IKBKG;APOE;APP GO:0006355| regulation of transcription, DNA-dependent HDAC8;INS;PARP1;ESR1;TP73;ENO1;IKBKG;TP53;HDAC4;HDAC1;EEF1A1 14210:[DB04998 DB01119] DB04998|AGRO100 IKBKG DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways 14211:[DB04998 DB00026] DB04998|AGRO100 IKBKG DB00026|Anakinra IL1R1 common genes common pathways GO:0006955| immune response IKBKG;IL1R1 14212:[DB04998 DB04908] DB04998|AGRO100 IKBKG DB04908|Flibanserin HTR1A;HTR2A;DRD4;CYP3A4 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;DRD4 GO:0016032| viral reproduction IKBKG;HTR2A 14213:[DB04998 DB00842] DB04998|AGRO100 IKBKG DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways GO:1901215| GABRB3;GABRB2;IKBKG 14214:[DB04998 DB04552] DB04998|AGRO100 IKBKG DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;PLA2G1B GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;IKBKG GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PLA2G1B 14215:[DB04998 DB00440] DB04998|AGRO100 IKBKG DB00440|Trimethoprim TYMS;DHFR;CYP3A4;CYP2C8;CYP2C9;ABCB1;SLC22A2 common genes common pathways 14216:[DB04998 DB00184] DB04998|AGRO100 IKBKG DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG GO:0009615| response to virus CYP1A1;IKBKG 14217:[DB04998 DB06777] DB04998|AGRO100 IKBKG DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR1I2;NR1H4 GO:0006954| inflammatory response IKBKG;NR1H4 GO:0006351| transcription, DNA-dependent NR1I2;IKBKG;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR1I2;NR1H4 GO:0045087| innate immune response IKBKG;NR1H4 14218:[DB04998 DB04630] DB04998|AGRO100 IKBKG DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006351| transcription, DNA-dependent NR3C2;IKBKG;NR3C1 GO:0006955| immune response IKBKG;CYP11B1 GO:0006355| regulation of transcription, DNA-dependent NR3C2;IKBKG;NR3C1 14219:[DB04998 DB00482] DB04998|AGRO100 IKBKG DB00482|Celecoxib PTGS2;PDPK1;CA2;CA3;ABCB5;ABCG2;ABCB1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;ABCC4;ABCB11 common genes common pathways GO:0038095| IKBKG;PDPK1 GO:0006954| inflammatory response PTGS2;IKBKG GO:0050852| T cell receptor signaling pathway PDPK1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;PDPK1 GO:0002223| stimulatory C-type lectin receptor signaling pathway PDPK1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PDPK1 14220:[DB04998 DB01035] DB04998|AGRO100 IKBKG DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent DNMT1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;DNMT1 14221:[DB04998 DB05969] DB04998|AGRO100 IKBKG DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;CDK7 GO:0006351| transcription, DNA-dependent CDK7;IKBKG GO:0006974| response to DNA damage stimulus CDK7;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;CDK7;VEGFA 14222:[DB04998 DB00809] DB04998|AGRO100 IKBKG DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways GO:0009615| response to virus IKBKG;CHRM2 14223:[DB04998 DB00648] DB04998|AGRO100 IKBKG DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0016579| protein deubiquitination IKBKG;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG;AR;ESR1 GO:0006351| transcription, DNA-dependent ESR1;AR;PGR;IKBKG GO:0006955| immune response CYP11B1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;PGR;IKBKG 14224:[DB04998 DB00004] DB04998|AGRO100 IKBKG DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0006915| apoptotic process IKBKG;IL2RA GO:0016032| viral reproduction IKBKG;IL2RB;IL2RG GO:0006955| immune response IKBKG;IL2RA;IL2RG GO:0006954| inflammatory response IKBKG;IL2RA 14225:[DB04998 DB05461] DB04998|AGRO100 IKBKG DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG 14226:[DB04998 DB01238] DB04998|AGRO100 IKBKG DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;DRD2;IKBKG GO:0009615| response to virus IKBKG;CHRM2 GO:0016032| viral reproduction HTR2A;IKBKG GO:0006954| inflammatory response HRH1;IKBKG GO:0000187| activation of MAPK activity DRD4;ADRA2B;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 14227:[DB04998 DB02901] DB04998|AGRO100 IKBKG DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0016579| protein deubiquitination AR;ESR1;IKBKG GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;IKBKG;NR3C2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006351| transcription, DNA-dependent NR3C2;IKBKG;ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;IKBKG 14228:[DB04998 DB06710] DB04998|AGRO100 IKBKG DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ESR1;AR GO:0016579| protein deubiquitination IKBKG;AR;ESR1 14229:[DB04998 DB07477] DB04998|AGRO100 IKBKG DB07477|Felbinac CTSL common genes common pathways 14230:[DB04998 DB01156] DB04998|AGRO100 IKBKG DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG 14231:[DB04998 DB00496] DB04998|AGRO100 IKBKG DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 14232:[DB04998 DB04070] DB04998|AGRO100 IKBKG DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways 14233:[DB04998 DB00807] DB04998|AGRO100 IKBKG DB00807|Proparacaine SCN10A common genes common pathways 14234:[DB04998 DB00318] DB04998|AGRO100 IKBKG DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1;OPRD1 14235:[DB04998 DB00443] DB04998|AGRO100 IKBKG DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways GO:0006915| apoptotic process IKBKG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 14236:[DB04998 DB01972] DB04998|AGRO100 IKBKG DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0006351| transcription, DNA-dependent HINT1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;HINT1 GO:0006915| apoptotic process HINT1;IKBKG 14237:[DB04998 DB01217] DB04998|AGRO100 IKBKG DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways 14238:[DB04998 DB06791] DB04998|AGRO100 IKBKG DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways 14239:[DB04998 DB01622] DB04998|AGRO100 IKBKG DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0016032| viral reproduction IKBKG;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0006915| apoptotic process ADRA1A;IKBKG 14240:[DB04998 DB09286] DB04998|AGRO100 IKBKG DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 GO:0016032| viral reproduction IKBKG;HTR2A GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity DRD4;IKBKG 14241:[DB04998 DB01062] DB04998|AGRO100 IKBKG DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 14242:[DB04998 DB00780] DB04998|AGRO100 IKBKG DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways GO:0006954| inflammatory response AOC3;IKBKG 14243:[DB04998 DB05767] DB04998|AGRO100 IKBKG DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0002223| stimulatory C-type lectin receptor signaling pathway NFKB1;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;IKBKG;TNF GO:0051403| stress-activated MAPK cascade NFKB1;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;NFKB2;NFKB1 GO:0009615| response to virus TNF;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;IL1B;IKBKG;TNF;NFKB2;NFKB1 GO:0045087| innate immune response NFKB2;IKBKG;NFKB1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;NFKB2;IKBKG GO:0050852| T cell receptor signaling pathway NFKB1;IKBKG GO:0006954| inflammatory response TNF;NFKB2;IL6;IL1B;IKBKG;NFKB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;NFKB2;IL1B;IKBKG;IL6;NFKB1 GO:0006955| immune response IL6;IL1B;IKBKG;TNF GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;TNF GO:0007249| I-kappaB kinase/NF-kappaB cascade NFKB1;IKBKG;NFKB2;TNF GO:0038095| IKBKG;NFKB1 GO:0007254| JNK cascade TNF;IKBKG GO:0006915| apoptotic process IL1B;IKBKG;NFKB1 GO:0000187| activation of MAPK activity IKBKG;IL1B;TNF 14244:[DB04998 DB06820] DB04998|AGRO100 IKBKG DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways 14245:[DB04998 DB01320] DB04998|AGRO100 IKBKG DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways 14246:[DB04998 DB00933] DB04998|AGRO100 IKBKG DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG 14247:[DB04998 DB00500] DB04998|AGRO100 IKBKG DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 14248:[DB04998 DB00804] DB04998|AGRO100 IKBKG DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0009615| response to virus CHRM2;CYP1A1;IKBKG 14249:[DB04998 DB01388] DB04998|AGRO100 IKBKG DB01388|Mibefradil CACNA1G;CACNA1H;CACNA1C;CACNA1D;CACNA1F;CACNA1I;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP1A1;ABCB1 common genes common pathways GO:0050852| T cell receptor signaling pathway CACNB3;IKBKG GO:0006955| immune response CYP11B1;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 14250:[DB04998 DB00106] DB04998|AGRO100 IKBKG DB00106|Abarelix GNRHR common genes common pathways 14251:[DB04998 DB00014] DB04998|AGRO100 IKBKG DB00014|Goserelin LHCGR;GNRHR common genes common pathways 14252:[DB04998 DB01115] DB04998|AGRO100 IKBKG DB01115|Nifedipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CALM1;KCNA1;CACNA1H;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2A6;CYP2C8;CYP2D6;CYP2E1;CYP1A1;CYP2B6;ABCC3;ABCB1;ABCC2;SLCO1B1;ABCB11 common genes common pathways GO:0038095| CALM1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0009615| response to virus IKBKG;CYP1A1 GO:0006351| transcription, DNA-dependent IKBKG;NR1I2 14253:[DB04998 DB14062] DB04998|AGRO100 IKBKG DB14062|Concanamycin A ABCB1 common genes common pathways 14254:[DB04998 DB09118] DB04998|AGRO100 IKBKG DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 14255:[DB04998 DB11943] DB04998|AGRO100 IKBKG DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways 14256:[DB04998 DB01558] DB04998|AGRO100 IKBKG DB01558|Bromazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 14257:[DB04998 DB08932] DB04998|AGRO100 IKBKG DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes common pathways 14258:[DB04998 DB13975] DB04998|AGRO100 IKBKG DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways 14259:[DB04998 DB00042] DB04998|AGRO100 IKBKG DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 14260:[DB04998 DB00254] DB04998|AGRO100 IKBKG DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006955| immune response IKBKG;B2M GO:0006355| regulation of transcription, DNA-dependent IKBKG;PADI4 GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent B2M;IKBKG GO:0045087| innate immune response PADI4;B2M;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;PADI4 14261:[DB04998 DB00938] DB04998|AGRO100 IKBKG DB00938|Salmeterol ADRB2;ADRB1;ADRB3;CYP3A4;CYP3A5;CYP3A7;CYP2C8 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;ADRB2 14262:[DB04998 DB13955] DB04998|AGRO100 IKBKG DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;IKBKG;ESR2;ESRRG;NR1I2;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;GPER1;NR1I2;NCOA2;IKBKG;ESR2;ESRRG GO:0009615| response to virus CYP1A1;IKBKG GO:0045087| innate immune response GPER1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG;ESR2;ESRRG;NR1I2;NCOA2 GO:0006954| inflammatory response IKBKG;GPER1 GO:0016032| viral reproduction BECN1;IKBKG GO:0006915| apoptotic process IKBKG;BECN1;GPER1 GO:0016579| protein deubiquitination BECN1;IKBKG;ESR1 14263:[DB04998 DB00546] DB04998|AGRO100 IKBKG DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 14264:[DB04998 DB14700] DB04998|AGRO100 IKBKG DB14700|Damoctocog alfa pegol F8 common genes common pathways 14265:[DB04998 DB09381] DB04998|AGRO100 IKBKG DB09381|Estrogens, esterified CYP3A4 common genes common pathways 14266:[DB04998 DB00418] DB04998|AGRO100 IKBKG DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GRIN1 14267:[DB04998 DB09095] DB04998|AGRO100 IKBKG DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent IKBKG;NR3C1 GO:0006915| apoptotic process NR3C1;IKBKG 14268:[DB04998 DB13345] DB04998|AGRO100 IKBKG DB13345|Dihydroergocristine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD1;DRD5;DRD2;DRD3;DRD4;CYP3A4;ABCB11 common genes common pathways GO:0016579| protein deubiquitination IKBKG;ADRB2 GO:0006915| apoptotic process IKBKG;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;IKBKG;DRD2;DRD3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0016032| viral reproduction HTR2A;IKBKG 14269:[DB04998 DB06623] DB04998|AGRO100 IKBKG DB06623|Flupirtine ADRA2A common genes common pathways 14270:[DB04998 DB00428] DB04998|AGRO100 IKBKG DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 14271:[DB04998 DB09244] DB04998|AGRO100 IKBKG DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways 14272:[DB04998 DB00387] DB04998|AGRO100 IKBKG DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 14273:[DB04998 DB11718] DB04998|AGRO100 IKBKG DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006974| response to DNA damage stimulus CCND1;IKBKG GO:0006351| transcription, DNA-dependent CCND1;IKBKG GO:0050852| T cell receptor signaling pathway BRAF;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;CCND1 14274:[DB04998 DB05133] DB04998|AGRO100 IKBKG DB05133|VP025 IL1B common genes common pathways GO:0000187| activation of MAPK activity IKBKG;IL1B GO:0006915| apoptotic process IKBKG;IL1B GO:0006954| inflammatory response IKBKG;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;IL1B GO:0006955| immune response IKBKG;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;IL1B 14275:[DB04998 DB00956] DB04998|AGRO100 IKBKG DB00956|Hydrocodone OPRM1;OPRD1;CYP2D6;CYP3A4 common genes common pathways GO:0006955| immune response OPRD1;IKBKG 14276:[DB04998 DB01235] DB04998|AGRO100 IKBKG DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0000187| activation of MAPK activity DRD4;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG;DRD3 14277:[DB04998 DB02709] DB04998|AGRO100 IKBKG DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes common pathways GO:0007249| I-kappaB kinase/NF-kappaB cascade IKBKG;AKT1 GO:0000187| activation of MAPK activity APP;IKBKG GO:0006915| apoptotic process IKBKG;SNCA;YARS;AHR;APP;AKT1;CSNK2A1 GO:0016579| protein deubiquitination ESR1;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;PPARG;AHR;IKBKG;PPARA;ESR1;NR1I3;CSNK2A1;KHSRP GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;APP;NR1I2;PPARG;IKBKG;NR1I3;AKT1;ESR1;PPARA GO:0009615| response to virus IKBKG;CYP1A1 GO:0045087| innate immune response IKBKG;APP;PPARG GO:0006974| response to DNA damage stimulus IKBKG;AKT1 GO:0006355| regulation of transcription, DNA-dependent AHR;PPARG;NR1I2;IKBKG;CSNK2A1;NR1I3;ESR1;PPARA;KHSRP GO:1901215| AKT1;PPARA;IKBKG;SNCA;APP GO:0043276| anoikis AKT1;IKBKG GO:0006954| inflammatory response AKT1;PTGS2;ALOX5;PTGS1;ALOX15;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;IKBKG GO:0016032| viral reproduction ITGA5;IKBKG;ITGB3 14278:[DB04998 DB00590] DB04998|AGRO100 IKBKG DB00590|Doxazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;CYP2C19;CYP2D6;CYP3A4;ORM1;ABCB1;SLC22A1 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 14279:[DB04998 DB01278] DB04998|AGRO100 IKBKG DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways 14280:[DB04998 DB00333] DB04998|AGRO100 IKBKG DB00333|Methadone OPRM1;GRIN3A;CHRNA10;OPRD1;HTR3A;LY96;ORM2;CYP3A4;CYP2C19;CYP3A5;CYP3A7;CYP2D6;CYP2B6;CYP2C8;CYP19A1;CYP1A2;CYP2C18;CYP2C9;ABCB1 common genes common pathways GO:0006955| immune response OPRD1;IKBKG GO:0006954| inflammatory response LY96;IKBKG GO:0045087| innate immune response LY96;IKBKG GO:0002756| MyD88-independent toll-like receptor signaling pathway IKBKG;LY96 GO:0007249| I-kappaB kinase/NF-kappaB cascade LY96;IKBKG GO:0035666| TRIF-dependent toll-like receptor signaling pathway LY96;IKBKG 14281:[DB04998 DB01348] DB04998|AGRO100 IKBKG DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways 14282:[DB04998 DB00961] DB04998|AGRO100 IKBKG DB00961|Mepivacaine SCN10A common genes common pathways 14283:[DB04998 DB09054] DB04998|AGRO100 IKBKG DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways 14284:[DB04998 DB06825] DB04998|AGRO100 IKBKG DB06825|Triptorelin GNRHR common genes common pathways 14285:[DB04998 DB01565] DB04998|AGRO100 IKBKG DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TRIM13;IKBKG GO:0045087| innate immune response TRIM13;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;POMC GO:0016239| positive regulation of macroautophagy TRIM13;IKBKG GO:0006955| immune response IKBKG;OPRK1;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TRIM13 14286:[DB04998 DB14575] DB04998|AGRO100 IKBKG DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways 14287:[DB04998 DB01601] DB04998|AGRO100 IKBKG DB01601|Lopinavir pol;CYP3A4;CYP2D6;CYP2C19;CYP2B6;CYP2C9;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways 14288:[DB04998 DB09270] DB04998|AGRO100 IKBKG DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways GO:0016032| viral reproduction LDLR;IKBKG 14289:[DB04998 DB05675] DB04998|AGRO100 IKBKG DB05675|EP-2104R FGA common genes common pathways GO:0045087| innate immune response FGA;IKBKG 14290:[DB04998 DB00327] DB04998|AGRO100 IKBKG DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways GO:0006955| immune response IKBKG;OPRK1;OPRD1 GO:0006954| inflammatory response IKBKG;PTGS1 14291:[DB04998 DB08439] DB04998|AGRO100 IKBKG DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0045087| innate immune response LTF;IKBKG GO:0006351| transcription, DNA-dependent IKBKG;LTF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;LTF GO:0006954| inflammatory response IKBKG;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity LTF;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;LTF 14292:[DB04998 DB00073] DB04998|AGRO100 IKBKG DB00073|Rituximab MS4A1 common genes common pathways 14293:[DB04998 DB06494] DB04998|AGRO100 IKBKG DB06494|Sufugolix GNRHR common genes common pathways 14294:[DB04998 DB05239] DB04998|AGRO100 IKBKG DB05239|Cobimetinib MAP2K1;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0000187| activation of MAPK activity MAP2K1;IKBKG 14295:[DB04998 DB02703] DB04998|AGRO100 IKBKG DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways 14296:[DB04998 DB00518] DB04998|AGRO100 IKBKG DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 14297:[DB04998 DB13835] DB04998|AGRO100 IKBKG DB13835|Caroverine CYP3A4 common genes common pathways 14298:[DB04998 DB01227] DB04998|AGRO100 IKBKG DB01227|Levacetylmethadol OPRM1;CHRNB4;CHRNA3;CYP3A5;CYP3A7;CYP3A4;CYP19A1 common genes common pathways 14299:[DB04998 DB00268] DB04998|AGRO100 IKBKG DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2;DRD3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;HTR2B GO:0016032| viral reproduction HTR2A;IKBKG GO:0000187| activation of MAPK activity ADRA2B;DRD4;IKBKG 14300:[DB04998 DB01196] DB04998|AGRO100 IKBKG DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways GO:0006351| transcription, DNA-dependent ESR1;ESR2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ESR2;ESR1 GO:0016579| protein deubiquitination ESR1;IKBKG 14301:[DB04998 DB11362] DB04998|AGRO100 IKBKG DB11362|Selexipag PTGIR;CES1;CYP2C8;CYP3A4;SLCO1B1;SLCO1B3;ABCB1 common genes common pathways 14302:[DB04998 DB01039] DB04998|AGRO100 IKBKG DB01039|Fenofibrate PPARA;PPARG;PPARD;NR1I2;CYP2C8;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARG;NR1I2;PPARA GO:0045087| innate immune response IKBKG;PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARD;IKBKG;NR1I2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARD;IKBKG;PPARG;NR1I2 GO:1901215| PPARA;IKBKG GO:0006915| apoptotic process PPARD;IKBKG 14303:[DB04998 DB06263] DB04998|AGRO100 IKBKG DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TOP2A GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 14304:[DB04998 DB00186] DB04998|AGRO100 IKBKG DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0006915| apoptotic process IKBKG;TSPO GO:1901215| GABRB3;GABRB2;IKBKG 14305:[DB04998 DB05710] DB04998|AGRO100 IKBKG DB05710|Gantacurium Chloride CHRNA3 common genes common pathways 14306:[DB04998 DB00426] DB04998|AGRO100 IKBKG DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways 14307:[DB04998 DB06809] DB04998|AGRO100 IKBKG DB06809|Plerixafor CXCR4 common genes common pathways GO:0000187| activation of MAPK activity CXCR4;IKBKG GO:0006915| apoptotic process IKBKG;CXCR4 GO:0006954| inflammatory response IKBKG;CXCR4 GO:0016032| viral reproduction IKBKG;CXCR4 GO:0009615| response to virus IKBKG;CXCR4 14308:[DB04998 DB01082] DB04998|AGRO100 IKBKG DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways GO:0045087| innate immune response IKBKG;PADI4 GO:0006351| transcription, DNA-dependent IKBKG;PADI4 GO:0006355| regulation of transcription, DNA-dependent IKBKG;PADI4 14309:[DB04998 DB00753] DB04998|AGRO100 IKBKG DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;ATP2C1 GO:0038095| IKBKG;CALM1 14310:[DB04998 DB01140] DB04998|AGRO100 IKBKG DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways 14311:[DB04998 DB12161] DB04998|AGRO100 IKBKG DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways 14312:[DB04998 DB05432] DB04998|AGRO100 IKBKG DB05432|DAS-431 IV CALY common genes common pathways 14313:[DB04998 DB08909] DB04998|AGRO100 IKBKG DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways 14314:[DB04998 DB13125] DB04998|AGRO100 IKBKG DB13125|Lusutrombopag MPL;CYP4A11;ABCB1;ABCG2 common genes common pathways 14315:[DB04998 DB01201] DB04998|AGRO100 IKBKG DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways 14316:[DB04998 DB00688] DB04998|AGRO100 IKBKG DB00688|Mycophenolate mofetil IMPDH1;IMPDH2;UGT1A1;UGT1A7;UGT1A6;UGT1A9;UGT2B7;UGT1A8;UGT1A10;CES1;CES2;CYP3A4;CYP3A5;CYP2C8;ALB;SLCO1B1;SLCO1B3;ABCC2;ABCG2;ABCB1 common genes common pathways 14317:[DB04998 DB00747] DB04998|AGRO100 IKBKG DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0009615| response to virus CHRM2;IKBKG 14318:[DB04998 DB01117] DB04998|AGRO100 IKBKG DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways 14319:[DB04998 DB04855] DB04998|AGRO100 IKBKG DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0050852| T cell receptor signaling pathway CACNB3;IKBKG 14320:[DB04998 DB00343] DB04998|AGRO100 IKBKG DB00343|Diltiazem CACNG1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2D6;CYP2C8;ABCB1 common genes common pathways 14321:[DB04998 DB04065] DB04998|AGRO100 IKBKG DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways 14322:[DB04998 DB00844] DB04998|AGRO100 IKBKG DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0006955| immune response IKBKG;OPRK1;OPRD1 14323:[DB04998 DB00624] DB04998|AGRO100 IKBKG DB00624|Testosterone AR;ESR1;NR3C2;CYP3A5;CYP19A1;CYP11A1;MAOA;CYP3A7;CYP3A4;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes common pathways GO:0016032| viral reproduction SLC10A1;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;NR3C2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0006351| transcription, DNA-dependent NR3C2;IKBKG;ESR1;AR GO:0016579| protein deubiquitination IKBKG;ESR1;AR 14324:[DB04998 DB01112] DB04998|AGRO100 IKBKG DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways 14325:[DB04998 DB00934] DB04998|AGRO100 IKBKG DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0006954| inflammatory response IKBKG;ORM1;HRH1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0009615| response to virus IKBKG;CHRM2 GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process IKBKG;ADRA1A 14326:[DB04998 DB11386] DB04998|AGRO100 IKBKG DB11386|Chlorobutanol KCNH2 common genes common pathways 14327:[DB04998 DB13951] DB04998|AGRO100 IKBKG DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR3C2;IKBKG;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;IKBKG GO:0006351| transcription, DNA-dependent AR;ESR1;NR3C2;IKBKG GO:0016579| protein deubiquitination IKBKG;ESR1;AR 14328:[DB04998 DB14003] DB04998|AGRO100 IKBKG DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0006351| transcription, DNA-dependent SEC14L2;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;SEC14L2 GO:0016032| viral reproduction SCARB1;LDLR;IKBKG 14329:[DB04998 DB09128] DB04998|AGRO100 IKBKG DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;IKBKG GO:0016032| viral reproduction IKBKG;HTR2A 14330:[DB04998 DB09202] DB04998|AGRO100 IKBKG DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0000187| activation of MAPK activity ADRA2B;IKBKG GO:0006915| apoptotic process ADRA1A;IKBKG 14331:[DB04998 DB11642] DB04998|AGRO100 IKBKG DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways 14332:[DB04998 DB07177] DB04998|AGRO100 IKBKG DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 14333:[DB04998 DB03793] DB04998|AGRO100 IKBKG DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0006915| apoptotic process IKBKG;PRDX5 GO:0006954| inflammatory response IKBKG;PRDX5 14334:[DB04998 DB02925] DB04998|AGRO100 IKBKG DB02925|Piretanide SLC12A1 common genes common pathways 14335:[DB04998 DB06273] DB04998|AGRO100 IKBKG DB06273|Tocilizumab IL6R;CYP3A4 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;IL6R 14336:[DB04998 DB13501] DB04998|AGRO100 IKBKG DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS1;PTGS2;IKBKG 14337:[DB04998 DB00603] DB04998|AGRO100 IKBKG DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways GO:0016579| protein deubiquitination ESR1;IKBKG GO:0006355| regulation of transcription, DNA-dependent ESR1;IKBKG;PGR GO:0006351| transcription, DNA-dependent PGR;IKBKG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;IKBKG;PGR 14338:[DB04998 DB06480] DB04998|AGRO100 IKBKG DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways 14339:[DB04998 DB13293] DB04998|AGRO100 IKBKG DB13293|Ipecac CYP2D6;CYP3A4 common genes common pathways 14340:[DB04998 DB00472] DB04998|AGRO100 IKBKG DB00472|Fluoxetine SLC6A4;KCNH2;HTR2C;CKS1B;CHRNA2;CHRNA3;CHRNB4;CYP2C19;CYP2D6;CYP2C9;CYP2B;CYP1A2;CYP3A4;CYP2B6;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CKS1B;IKBKG GO:0006954| inflammatory response ORM1;IKBKG 14341:[DB04998 DB01250] DB04998|AGRO100 IKBKG DB01250|Olsalazine TPMT;IFNG common genes common pathways GO:0006955| immune response IFNG;IKBKG GO:0009615| response to virus IFNG;IKBKG GO:0006915| apoptotic process IFNG;IKBKG 14342:[DB04998 DB00881] DB04998|AGRO100 IKBKG DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways 14343:[DB04998 DB00170] DB04998|AGRO100 IKBKG DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0009615| response to virus CYP1A1;IKBKG 14344:[DB04998 DB06403] DB04998|AGRO100 IKBKG DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways 14345:[DB04998 DB01333] DB04998|AGRO100 IKBKG DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways 14346:[DB04998 DB01339] DB04998|AGRO100 IKBKG DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways 14347:[DB04998 DB13857] DB04998|AGRO100 IKBKG DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0006351| transcription, DNA-dependent PGR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PGR GO:0006355| regulation of transcription, DNA-dependent IKBKG;PGR 14348:[DB04998 DB05939] DB04998|AGRO100 IKBKG DB05939|MK-0354 GPER1 common genes common pathways GO:0006954| inflammatory response IKBKG;GPER1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;GPER1 GO:0045087| innate immune response IKBKG;GPER1 GO:0006915| apoptotic process GPER1;IKBKG 14349:[DB04998 DB06168] DB04998|AGRO100 IKBKG DB06168|Canakinumab IL1B common genes common pathways GO:0006915| apoptotic process IKBKG;IL1B GO:0000187| activation of MAPK activity IL1B;IKBKG GO:0006955| immune response IKBKG;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;IL1B GO:0006954| inflammatory response IL1B;IKBKG GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IKBKG 14350:[DB04998 DB00952] DB04998|AGRO100 IKBKG DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways 14351:[DB04998 DB00909] DB04998|AGRO100 IKBKG DB00909|Zonisamide SCN1A;SCN2A;SCN3A;SCN4A;SCN5A;SCN9A;SCN11A;SCN1B;SCN2B;SCN3B;SCN4B;CACNA1G;CACNA1H;CACNA1I;CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA8;CA9;CA10;CA11;CA12;CA13;CA14;MAOB;MAOA;CYP3A4;AOX1;CYP2C19;UGT1A1;CYP3A5 common genes common pathways GO:0006954| inflammatory response SCN9A;IKBKG 14352:[DB04998 DB00222] DB04998|AGRO100 IKBKG DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways 14353:[DB04998 DB00721] DB04998|AGRO100 IKBKG DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways 14354:[DB04998 DB00273] DB04998|AGRO100 IKBKG DB00273|Topiramate GABRA1;SCN1A;GRIK1;CA2;CA4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CA1;CA3;CYP2C19;CYP3A4 common genes common pathways GO:1901215| IKBKG;GABRB2;GABRB3 14355:[DB04998 DB14507] DB04998|AGRO100 IKBKG DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:1901215| GSK3B;IKBKG 14356:[DB04998 DB01195] DB04998|AGRO100 IKBKG DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways 14357:[DB04998 DB11071] DB04998|AGRO100 IKBKG DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response PTGS2;PTGS1;IKBKG 14358:[DB04998 DB05232] DB04998|AGRO100 IKBKG DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways 14359:[DB04998 DB00056] DB04998|AGRO100 IKBKG DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent FCGR1A;IKBKG GO:0045087| innate immune response FCGR1A;IKBKG;C1R;C1QB;C1QA;C1QC;C1S GO:0016032| viral reproduction FCGR2B;IKBKG GO:0006955| immune response FCGR3A;FCGR2C;C1QC;C1R;FCGR3B;FCGR2B;FCGR1A;IKBKG GO:0006954| inflammatory response FCGR2B;IKBKG 14360:[DB04998 DB00996] DB04998|AGRO100 IKBKG DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0006954| inflammatory response ADORA1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKG 14361:[DB04998 DB08970] DB04998|AGRO100 IKBKG DB08970|Fluprednidene CYP3A4 common genes common pathways 14362:[DB04998 DB06637] DB04998|AGRO100 IKBKG DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways 14363:[DB04998 DB00027] DB04998|AGRO100 IKBKG DB00027|Gramicidin D ABCB1 common genes common pathways 14364:[DB04998 DB00722] DB04998|AGRO100 IKBKG DB00722|Lisinopril ACE common genes common pathways 14365:[DB04998 DB06207] DB04998|AGRO100 IKBKG DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0006915| apoptotic process ADRA1A;IKBKG 14366:[DB04998 DB01259] DB04998|AGRO100 IKBKG DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;TAP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;EGFR GO:0006351| transcription, DNA-dependent IKBKG;ERBB2 GO:0016032| viral reproduction TAP1;IKBKG GO:0006355| regulation of transcription, DNA-dependent IKBKG;ERBB2 14367:[DB04998 DB01406] DB04998|AGRO100 IKBKG DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0016579| protein deubiquitination IKBKG;AR;ESR1 GO:0006955| immune response IKBKG;CCL2 GO:0006954| inflammatory response IKBKG;CCL2 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;AR GO:0006355| regulation of transcription, DNA-dependent PGR;IKBKG;AR;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;IKBKG;AR;ESR1 GO:0006351| transcription, DNA-dependent ESR1;AR;PGR;IKBKG 14368:[DB04998 DB00862] DB04998|AGRO100 IKBKG DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0000187| activation of MAPK activity PDE6G;IKBKG;PDE6H 14369:[DB04998 DB01215] DB04998|AGRO100 IKBKG DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:1901215| GABRB3;IKBKG;GABRB2 14370:[DB04998 DB00448] DB04998|AGRO100 IKBKG DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 14371:[DB04998 DB01181] DB04998|AGRO100 IKBKG DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways GO:0006954| inflammatory response PTGS1;IKBKG GO:0006355| regulation of transcription, DNA-dependent NR1I2;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;IKBKG GO:0006351| transcription, DNA-dependent NR1I2;IKBKG 14372:[DB04998 DB06708] DB04998|AGRO100 IKBKG DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways 14373:[DB04998 DB00672] DB04998|AGRO100 IKBKG DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006954| inflammatory response PTGS1;IKBKG 14374:[DB04998 DB11079] DB04998|AGRO100 IKBKG DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS1;PTGS2 14375:[DB04998 DB08437] DB04998|AGRO100 IKBKG DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;RPL23 14376:[DB04998 DB13170] DB04998|AGRO100 IKBKG DB13170|Plecanatide GUCY1A2 common genes common pathways 14377:[DB04998 DB01073] DB04998|AGRO100 IKBKG DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0016032| viral reproduction POLA1;IKBKG 14378:[DB04998 DB00436] DB04998|AGRO100 IKBKG DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways 14379:[DB04998 DB00092] DB04998|AGRO100 IKBKG DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways GO:0006955| immune response C1QC;FCGR3A;FCGR2C;FCGR3B;FCGR2B;C1R;FCGR1A;IKBKG GO:0016032| viral reproduction FCGR2B;IKBKG GO:0006954| inflammatory response IKBKG;FCGR2B GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent IKBKG;FCGR1A GO:0045087| innate immune response C1QC;C1QA;C1QB;C1R;FCGR1A;IKBKG GO:0006915| apoptotic process IKBKG;CD2 14380:[DB04998 DB13983] DB04998|AGRO100 IKBKG DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways 14381:[DB04998 DB00990] DB04998|AGRO100 IKBKG DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways 14382:[DB04998 DB11750] DB04998|AGRO100 IKBKG DB11750|Clobetasol CYP3A4 common genes common pathways 14383:[DB04998 DB00484] DB04998|AGRO100 IKBKG DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0000187| activation of MAPK activity IKBKG;ADRA2B 14384:[DB04998 DB05207] DB04998|AGRO100 IKBKG DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0007254| JNK cascade IKBKG;TNF GO:0000187| activation of MAPK activity TNF;IKBKG GO:0007249| I-kappaB kinase/NF-kappaB cascade TNF;IKBKG GO:0010803| regulation of tumor necrosis factor-mediated signaling pathway IKBKG;TNF GO:0006955| immune response IL1R1;IKBKG;TNF GO:0006954| inflammatory response TNF;IKBKG GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IKBKG GO:0009615| response to virus TNF;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNF 14385:[DB04998 DB11737] DB04998|AGRO100 IKBKG DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;IKBKG 14386:[DB04998 DB11098] DB04998|AGRO100 IKBKG DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways 14387:[DB04998 DB00316] DB04998|AGRO100 IKBKG DB00316|Acetaminophen PTGS2;PTGS1;FAAH;TRPV1;GSTP1;CYP2E1;CYP1A2;CYP3A4;CYP2D6;CYP1A1;CYP2A6;CYP2C8;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9;SLC22A6;ABCB1 common genes common pathways GO:0009615| response to virus IKBKG;CYP1A1 GO:0006954| inflammatory response PTGS1;PTGS2;TRPV1;IKBKG GO:1901215| IKBKG;SULT1A3 14388:[DB04998 DB09297] DB04998|AGRO100 IKBKG DB09297|Paritaprevir CYP3A4;CYP3A5;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways 14389:[DB04998 DB00905] DB04998|AGRO100 IKBKG DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways 14390:[DB04998 DB01225] DB04998|AGRO100 IKBKG DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways 14391:[DB04998 DB01020] DB04998|AGRO100 IKBKG DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways 14392:[DB04998 DB01260] DB04998|AGRO100 IKBKG DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;IKBKG GO:0006915| apoptotic process IKBKG;NR3C1 14393:[DB04998 DB05624] DB04998|AGRO100 IKBKG DB05624|Teverelix GNRHR common genes common pathways 14394:[DB04998 DB01065] DB04998|AGRO100 IKBKG DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0016579| protein deubiquitination ESR1;IKBKG GO:0038095| IKBKG;CALM1 GO:0006954| inflammatory response IDO1;IKBKG GO:0006355| regulation of transcription, DNA-dependent CALR;RORB;IKBKG;ESR1 GO:0002479| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent CALR;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;RORB;IKBKG GO:0006351| transcription, DNA-dependent ESR1;IKBKG;RORB 14395:[DB04998 DB04830] DB04998|AGRO100 IKBKG DB04830|Buformin SLC22A1 common genes common pathways 14396:[DB04998 DB06681] DB04998|AGRO100 IKBKG DB06681|Belatacept CD86;CD80 common genes common pathways GO:0016032| viral reproduction CD80;CD86;IKBKG GO:0006955| immune response IKBKG;CD86 14397:[DB04998 DB01535] DB04998|AGRO100 IKBKG DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response OPRD1;IKBKG;OPRK1 14398:[DB04998 DB00679] DB04998|AGRO100 IKBKG DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0016032| viral reproduction HTR2A;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;DRD2 GO:0006915| apoptotic process ADRA1A;IKBKG 14399:[DB04998 DB00280] DB04998|AGRO100 IKBKG DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0006954| inflammatory response ORM1;IKBKG GO:0009615| response to virus CHRM2;IKBKG 14400:[DB04998 DB06897] DB04998|AGRO100 IKBKG DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways 14401:[DB04998 DB01381] DB04998|AGRO100 IKBKG DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:1901215| IKBKG;GABRB2 14402:[DB04998 DB01208] DB04998|AGRO100 IKBKG DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;IKBKG GO:0006974| response to DNA damage stimulus TOP2A;IKBKG 14403:[DB04998 DB01283] DB04998|AGRO100 IKBKG DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways GO:0006954| inflammatory response IKBKG;PTGS2;PTGS1 14404:[DB04998 DB01166] DB04998|AGRO100 IKBKG DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways 14405:[DB04998 DB05311] DB04998|AGRO100 IKBKG DB05311|Ecallantide KLKB1 common genes common pathways GO:0006954| inflammatory response IKBKG;KLKB1 14406:[DB04998 DB01241] DB04998|AGRO100 IKBKG DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:1901215| IKBKG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;IKBKG GO:0006351| transcription, DNA-dependent PPARA;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;PPARA 14407:[DB04998 DB00778] DB04998|AGRO100 IKBKG DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways 14408:[DB04998 DB11475] DB04998|AGRO100 IKBKG DB11475|Tylosin CYP3A4 common genes common pathways 14409:[DB04998 DB05465] DB04998|AGRO100 IKBKG DB05465|Tandutinib FLT3;PDGFD common genes common pathways 14410:[DB04998 DB00181] DB04998|AGRO100 IKBKG DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways 14411:[DB04998 DB04839] DB04998|AGRO100 IKBKG DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent IKBKG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;IKBKG GO:0006351| transcription, DNA-dependent AR;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;AR GO:0016579| protein deubiquitination IKBKG;AR 14412:[DB04998 DB01276] DB04998|AGRO100 IKBKG DB01276|Exenatide GLP1R;ALB common genes common pathways 14413:[DB04998 DB01949] DB04998|AGRO100 IKBKG DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 14414:[DB07307 DB00540] DB07307|N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide MAPK14 DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0007265| Ras protein signal transduction MAPK14;ADRA2A GO:0007166| cell surface receptor linked signaling pathway CHRM4;MAPK14;ADRB2 GO:0032496| response to lipopolysaccharide CYP1A2;MAPK14 GO:0043312| neutrophil degranulation ORM1;MAPK14;PGRMC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MAPK14;DRD2;ADRB2 GO:0035556| intracellular signal transduction MAPK14;DRD2;ADRA1A;ADRA1B GO:0007165| signal transduction CHRM2;ADRA2B;ADRB2;HTR2A;CHRM1;ADRA2C;HTR1A;HRH1;CHRM5;ADRA1B;MAPK14;CHRM3;ADRA1D;ADRB3;ADRA2A;HTR2C;HTR6;CHRM4;DRD2;ADRA1A;ADRB1 GO:0006915| apoptotic process ADRA1A;MAPK14 GO:0000187| activation of MAPK activity ADRA2B;MAPK14 GO:0006928| cellular component movement MAPK14;ADRA2A GO:0010628| positive regulation of gene expression MAPK14;SLC6A4 14415:[DB07307 DB01151] DB07307|N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide MAPK14 DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0043312| neutrophil degranulation MAPK14;ORM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MAPK14;ADRB2 GO:0035556| intracellular signal transduction DRD2;ADRA1A;MAPK14;ADRA1B GO:0007166| cell surface receptor linked signaling pathway ADRB2;MAPK14;CHRM4 GO:0007265| Ras protein signal transduction MAPK14;ADRA2A GO:0032496| response to lipopolysaccharide CYP1A2;MAPK14 GO:0007165| signal transduction SMPD1;CHRM3;ADRA1D;MAPK14;CHRM4;ADRB1;ADRA1A;DRD2;HTR2C;ADRA2A;HRH1;CHRM5;HTR2A;ADRB2;ADRA2B;CHRM2;HTR1A;ADRA2C;CHRM1;ADRA1B GO:0010628| positive regulation of gene expression MAPK14;SLC6A4 GO:0006928| cellular component movement MAPK14;ADRA2A GO:0000187| activation of MAPK activity MAPK14;ADRA2B GO:0006915| apoptotic process MAPK14;ADRA1A 14416:[DB07307 DB00571] DB07307|N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide MAPK14 DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0043312| neutrophil degranulation ORM1;MAPK14 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MAPK14;ADRB2 GO:0007166| cell surface receptor linked signaling pathway MAPK14;ADRB2 GO:0032496| response to lipopolysaccharide MAPK14;CYP1A1;CYP1A2 GO:0007165| signal transduction ADRB2;HTR1A;MAPK14;ADRB1;HTR1B;ADRB3 14417:[DB04833 DB07543] DB04833|Methaqualone CYP3A4 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways 14418:[DB04833 DB03685] DB04833|Methaqualone CYP3A4 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways 14419:[DB04833 DB01179] DB04833|Methaqualone CYP3A4 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways 14420:[DB04833 DB05127] DB04833|Methaqualone CYP3A4 DB05127|ANA971 TLR7 common genes common pathways 14421:[DB04833 DB03372] DB04833|Methaqualone CYP3A4 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways 14422:[DB04833 DB01148] DB04833|Methaqualone CYP3A4 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways 14423:[DB04833 DB09213] DB04833|Methaqualone CYP3A4 DB09213|Dexibuprofen PTGS2;PTGS1;BCL2;THBD;PLAT;FABP2;PPARG;CFTR;SLC15A1;PPARA;GP1BA;S100A7;CYP2C9;UGT1A1;UGT1A3;UGT1A9;UGT2B4;UGT2B7;CYP2C8;CYP2C19;AMACR;ALB;ABCC4;ABCC1;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLCO2B1;ABCB1 common genes common pathways GO:0017144| drug metabolic process UGT1A3;CYP3A4;CYP2C8;CYP2C19;CYP2C9;UGT1A1;UGT1A9 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;CYP2C19;CYP2C8;UGT1A1;CYP2C9 GO:0002933| CYP3A4;CYP2C8 GO:0006629| lipid metabolic process PPARA;CYP3A4;PTGS2;PTGS1;UGT2B7;PPARG;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;UGT2B4;CYP2C9;UGT1A9;CYP2C8;CYP2C19 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;ABCC4;PTGS2;CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 14424:[DB04833 DB06725] DB04833|Methaqualone CYP3A4 DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS2;PTGS1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PTGS1;PTGS2;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 14425:[DB04833 DB04863] DB04833|Methaqualone CYP3A4 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways 14426:[DB04833 DB00232] DB04833|Methaqualone CYP3A4 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways 14427:[DB04833 DB00725] DB04833|Methaqualone CYP3A4 DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways 14428:[DB04833 DB00838] DB04833|Methaqualone CYP3A4 DB00838|Clocortolone NR3C1 common genes common pathways 14429:[DB04833 DB06935] DB04833|Methaqualone CYP3A4 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways 14430:[DB04833 DB00087] DB04833|Methaqualone CYP3A4 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 14431:[DB04833 DB01415] DB04833|Methaqualone CYP3A4 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 14432:[DB04833 DB06803] DB04833|Methaqualone CYP3A4 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C9 14433:[DB04833 DB06914] DB04833|Methaqualone CYP3A4 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP3A4 14434:[DB04833 DB00175] DB04833|Methaqualone CYP3A4 DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process HMGCR;CYP3A4;CYP2C8 GO:0002933| CYP3A4;CYP2C8 GO:0006629| lipid metabolic process SLC16A1;HMGCR;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;HMGCR;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 14435:[DB04833 DB00940] DB04833|Methaqualone CYP3A4 DB00940|Methantheline CHRM1;HRH2 common genes common pathways 14436:[DB04833 DB01837] DB04833|Methaqualone CYP3A4 DB01837|O-acetyl-L-serine PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 14437:[DB04833 DB05943] DB04833|Methaqualone CYP3A4 DB05943|Resatorvid CSF2RB;IL2RG common genes common pathways 14438:[DB04833 DB09422] DB04833|Methaqualone CYP3A4 DB09422|Soybean oil PPARA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARA 14439:[DB04833 DB00098] DB04833|Methaqualone CYP3A4 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways 14440:[DB04833 DB03245] DB04833|Methaqualone CYP3A4 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GCDH 14441:[DB04833 DB00816] DB04833|Methaqualone CYP3A4 DB00816|Orciprenaline ADRB2 common genes common pathways 14442:[DB04833 DB01983] DB04833|Methaqualone CYP3A4 DB01983|2(S)-Amino-6-Boronohexanoic Acid ARG1 common genes common pathways 14443:[DB04833 DB04185] DB04833|Methaqualone CYP3A4 DB04185|Norvaline OTC;GATM common genes common pathways 14444:[DB04833 DB08962] DB04833|Methaqualone CYP3A4 DB08962|Glibornuride CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 14445:[DB04833 DB00936] DB04833|Methaqualone CYP3A4 DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;PTGS2;AKR1C1;CYP3A4;PTGS1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;SLC16A1;PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;PTGS1;CYP3A4;AKR1C1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 14446:[DB04833 DB01165] DB04833|Methaqualone CYP3A4 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 14447:[DB04833 DB00671] DB04833|Methaqualone CYP3A4 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 14448:[DB04833 DB01959] DB04833|Methaqualone CYP3A4 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways 14449:[DB04833 DB08894] DB04833|Methaqualone CYP3A4 DB08894|Peginesatide EPOR common genes common pathways 14450:[DB04833 DB07546] DB04833|Methaqualone CYP3A4 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways 14451:[DB04833 DB05111] DB04833|Methaqualone CYP3A4 DB05111|Fontolizumab IFNG common genes common pathways 14452:[DB04833 DB03600] DB04833|Methaqualone CYP3A4 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 14453:[DB04833 DB01436] DB04833|Methaqualone CYP3A4 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0036378| CYP27B1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP27B1;GC GO:0055114| oxidation-reduction process CYP27B1;CYP3A4 14454:[DB04833 DB08256] DB04833|Methaqualone CYP3A4 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4 GO:0017144| drug metabolic process EPHX2;CYP3A4 14455:[DB04833 DB07830] DB04833|Methaqualone CYP3A4 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways 14456:[DB04833 DB11785] DB04833|Methaqualone CYP3A4 DB11785|Anisodamine CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 14457:[DB04833 DB12450] DB04833|Methaqualone CYP3A4 DB12450|Propyl Gallate ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 14458:[DB04833 DB05258] DB04833|Methaqualone CYP3A4 DB05258|Natural alpha interferon IFNAR1 common genes common pathways 14459:[DB04833 DB08936] DB04833|Methaqualone CYP3A4 DB08936|Chlorcyclizine HRH1 common genes common pathways 14460:[DB04833 DB09160] DB04833|Methaqualone CYP3A4 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways 14461:[DB04833 DB12872] DB04833|Methaqualone CYP3A4 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0055114| oxidation-reduction process F8;CYP3A4 14462:[DB04833 DB00135] DB04833|Methaqualone CYP3A4 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process TH;CYP3A4 14463:[DB04833 DB02340] DB04833|Methaqualone CYP3A4 DB02340|N-Acetyl-Serine F13A1 common genes common pathways 14464:[DB04833 DB06477] DB04833|Methaqualone CYP3A4 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways 14465:[DB04833 DB02483] DB04833|Methaqualone CYP3A4 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0055114| oxidation-reduction process LDHA;CYP3A4 14466:[DB04833 DB07092] DB04833|Methaqualone CYP3A4 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways 14467:[DB04833 DB00654] DB04833|Methaqualone CYP3A4 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways 14468:[DB04833 DB04363] DB04833|Methaqualone CYP3A4 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;BLVRB 14469:[DB04833 DB00263] DB04833|Methaqualone CYP3A4 DB00263|Sulfisoxazole CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 14470:[DB04833 DB01099] DB04833|Methaqualone CYP3A4 DB01099|Flucytosine DNMT1 common genes common pathways 14471:[DB04833 DB02857] DB04833|Methaqualone CYP3A4 DB02857|Guanosine PNP common genes common pathways 14472:[DB04833 DB12836] DB04833|Methaqualone CYP3A4 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways 14473:[DB04833 DB00139] DB04833|Methaqualone CYP3A4 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process SDHC;ALDH5A1;P3H1;P4HA1;BBOX1;P3H2;PLOD1;P4HA2;SDHD;P3H3;SDHA;CYP3A4;TMLHE;HSD17B6;ASPH;PLOD3;SDHB GO:0006629| lipid metabolic process CYP3A4;HSD17B6 GO:0008202| steroid metabolic process CYP3A4;HSD17B6 14474:[DB04833 DB02110] DB04833|Methaqualone CYP3A4 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYCS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 14475:[DB04833 DB01854] DB04833|Methaqualone CYP3A4 DB01854|5-Bromonicotinamide ART1 common genes common pathways 14476:[DB04833 DB06156] DB04833|Methaqualone CYP3A4 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways 14477:[DB04833 DB01430] DB04833|Methaqualone CYP3A4 DB01430|Almitrine ATP1A1 common genes common pathways 14478:[DB04833 DB13164] DB04833|Methaqualone CYP3A4 DB13164|Olmutinib EGFR common genes common pathways 14479:[DB04833 DB09334] DB04833|Methaqualone CYP3A4 DB09334|Seractide acetate MC2R common genes common pathways 14480:[DB04833 DB03752] DB04833|Methaqualone CYP3A4 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 14481:[DB04833 DB08291] DB04833|Methaqualone CYP3A4 DB08291|N-(3-AMINOPROPYL)-2-NITROBENZENAMINE KAT2B common genes common pathways 14482:[DB04833 DB04614] DB04833|Methaqualone CYP3A4 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways 14483:[DB04833 DB00493] DB04833|Methaqualone CYP3A4 DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 14484:[DB04833 DB06848] DB04833|Methaqualone CYP3A4 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways 14485:[DB04833 DB08695] DB04833|Methaqualone CYP3A4 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HPGDS 14486:[DB04833 DB05785] DB04833|Methaqualone CYP3A4 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways 14487:[DB04833 DB02580] DB04833|Methaqualone CYP3A4 DB02580|Pentaglyme PFN2;gpmA;purA common genes common pathways 14488:[DB04833 DB00119] DB04833|Methaqualone CYP3A4 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PDHB GO:0006629| lipid metabolic process CYP3A4;PC;SLC16A1 14489:[DB04833 DB02623] DB04833|Methaqualone CYP3A4 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways 14490:[DB04833 DB01805] DB04833|Methaqualone CYP3A4 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways 14491:[DB04833 DB11201] DB04833|Methaqualone CYP3A4 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4 14492:[DB04833 DB02418] DB04833|Methaqualone CYP3A4 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways 14493:[DB04833 DB11626] DB04833|Methaqualone CYP3A4 DB11626|Tasonermin TNFRSF1A;TNFRSF1B common genes common pathways 14494:[DB04833 DB00392] DB04833|Methaqualone CYP3A4 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways 14495:[DB04833 DB08632] DB04833|Methaqualone CYP3A4 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways 14496:[DB04833 DB09559] DB04833|Methaqualone CYP3A4 DB09559|Necitumumab EGFR common genes common pathways 14497:[DB04833 DB00775] DB04833|Methaqualone CYP3A4 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways 14498:[DB04833 DB07297] DB04833|Methaqualone CYP3A4 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways 14499:[DB04833 DB03680] DB04833|Methaqualone CYP3A4 DB03680|Tartronate ME2;ME3 common genes common pathways GO:0055114| oxidation-reduction process ME2;CYP3A4;ME3 14500:[DB04833 DB00300] DB04833|Methaqualone CYP3A4 DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;CYP3A4 14501:[DB04833 DB01914] DB04833|Methaqualone CYP3A4 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways 14502:[DB04833 DB04005] DB04833|Methaqualone CYP3A4 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways 14503:[DB04833 DB00063] DB04833|Methaqualone CYP3A4 DB00063|Eptifibatide ITGB3 common genes common pathways 14504:[DB04833 DB00149] DB04833|Methaqualone CYP3A4 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways 14505:[DB04833 DB08251] DB04833|Methaqualone CYP3A4 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways 14506:[DB04833 DB01917] DB04833|Methaqualone CYP3A4 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways 14507:[DB04833 DB03256] DB04833|Methaqualone CYP3A4 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways 14508:[DB04833 DB08486] DB04833|Methaqualone CYP3A4 DB08486|Efaproxiral HBA1;HBB common genes common pathways 14509:[DB04833 DB08302] DB04833|Methaqualone CYP3A4 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 14510:[DB04833 DB07842] DB04833|Methaqualone CYP3A4 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 14511:[DB04833 DB09273] DB04833|Methaqualone CYP3A4 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 14512:[DB04833 DB05308] DB04833|Methaqualone CYP3A4 DB05308|ANX-510 TYMS common genes common pathways 14513:[DB04833 DB00290] DB04833|Methaqualone CYP3A4 DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways 14514:[DB04833 DB07302] DB04833|Methaqualone CYP3A4 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 14515:[DB04833 DB02166] DB04833|Methaqualone CYP3A4 DB02166|Propidium ACHE common genes common pathways 14516:[DB04833 DB14597] DB04833|Methaqualone CYP3A4 DB14597|Lanadelumab KLKB1 common genes common pathways 14517:[DB04833 DB07047] DB04833|Methaqualone CYP3A4 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways 14518:[DB04833 DB00945] DB04833|Methaqualone CYP3A4 DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;PRKAA1;CYP2C8;CYP2C19;CYP2C9;PRKAA2 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0002933| CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2C9;PTGS1;CYP3A4;AKR1C1 GO:0006629| lipid metabolic process PRKAA2;CYP2C9;PRKAA1;PRKAG2;PTGS2;PRKAG1;CYP3A4;PTGS1;PRKAG3;PRKAB2;PRKAB1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process PTGS1;AKR1C1;CYP3A4;PTGS2;CYP2C8;CYP2C19;CYP2C9 14519:[DB04833 DB09517] DB04833|Methaqualone CYP3A4 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways 14520:[DB04833 DB07144] DB04833|Methaqualone CYP3A4 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 14521:[DB04833 DB07670] DB04833|Methaqualone CYP3A4 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C18;CYP3A4 GO:0055114| oxidation-reduction process CYP2C18;CYP3A4 14522:[DB04833 DB06247] DB04833|Methaqualone CYP3A4 DB06247|CX516 GRIA1 common genes common pathways 14523:[DB04833 DB07740] DB04833|Methaqualone CYP3A4 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HMGCS1 GO:0008202| steroid metabolic process CYP3A4;HMGCS1 14524:[DB04833 DB02404] DB04833|Methaqualone CYP3A4 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways 14525:[DB04833 DB04469] DB04833|Methaqualone CYP3A4 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 14526:[DB04833 DB01124] DB04833|Methaqualone CYP3A4 DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0002933| CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C18;CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C18;CYP2C9;CYP2C19;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 14527:[DB04833 DB06530] DB04833|Methaqualone CYP3A4 DB06530|Resiquimod TLR7;TLR8 common genes common pathways 14528:[DB04833 DB06607] DB04833|Methaqualone CYP3A4 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways 14529:[DB04833 DB04801] DB04833|Methaqualone CYP3A4 DB04801|cis-Vaccenic acid PPARD common genes common pathways GO:0006629| lipid metabolic process PPARD;CYP3A4 14530:[DB04833 DB00266] DB04833|Methaqualone CYP3A4 DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process NQO1;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process VKORC1;CYP3A4;CYP2C9;NQO1;CRYZ GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;VKORC1;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 14531:[DB04833 DB09421] DB04833|Methaqualone CYP3A4 DB09421|Protirelin TRHR common genes common pathways 14532:[DB04833 DB00046] DB04833|Methaqualone CYP3A4 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways 14533:[DB04833 DB13783] DB04833|Methaqualone CYP3A4 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways GO:0006629| lipid metabolic process UGT2B7;PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 GO:0008202| steroid metabolic process CYP3A4;UGT2B7 14534:[DB04833 DB00800] DB04833|Methaqualone CYP3A4 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways 14535:[DB04833 DB07282] DB04833|Methaqualone CYP3A4 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways 14536:[DB04833 DB02427] DB04833|Methaqualone CYP3A4 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 14537:[DB04833 DB06694] DB04833|Methaqualone CYP3A4 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways 14538:[DB04833 DB05289] DB04833|Methaqualone CYP3A4 DB05289|Tarenflurbil IKBKG common genes common pathways 14539:[DB04833 DB00168] DB04833|Methaqualone CYP3A4 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006629| lipid metabolic process TRPV1;CYP3A4 14540:[DB04833 DB07873] DB04833|Methaqualone CYP3A4 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways 14541:[DB04833 DB12307] DB04833|Methaqualone CYP3A4 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP3A7 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A43;CYP3A4;CYP3A7;CYP3A5 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP3A5 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP3A4;CYP3A7 14542:[DB04833 DB11587] DB04833|Methaqualone CYP3A4 DB11587|Etafedrine ADRB2 common genes common pathways 14543:[DB04833 DB12436] DB04833|Methaqualone CYP3A4 DB12436|Vofopitant TACR1 common genes common pathways 14544:[DB04833 DB06920] DB04833|Methaqualone CYP3A4 DB06920|Eribaxaban F10 common genes common pathways 14545:[DB04833 DB04105] DB04833|Methaqualone CYP3A4 DB04105|N-Heptylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ADH1B 14546:[DB04833 DB05407] DB04833|Methaqualone CYP3A4 DB05407|TBC-3711 EDN1 common genes common pathways 14547:[DB04833 DB12555] DB04833|Methaqualone CYP3A4 DB12555|Nelotanserin HTR2A common genes common pathways 14548:[DB04833 DB06737] DB04833|Methaqualone CYP3A4 DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;UGT2B7;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PTGS1;UGT2B7;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS1 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 14549:[DB04833 DB08655] DB04833|Methaqualone CYP3A4 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways 14550:[DB04833 DB02360] DB04833|Methaqualone CYP3A4 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways 14551:[DB04833 DB07053] DB04833|Methaqualone CYP3A4 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 14552:[DB04833 DB01251] DB04833|Methaqualone CYP3A4 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 14553:[DB04833 DB04942] DB04833|Methaqualone CYP3A4 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways 14554:[DB04833 DB04725] DB04833|Methaqualone CYP3A4 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0002933| CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP3A4;UGT1A3 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process PTGS2;CYP2J2;CYP3A4;ALOX5;CYP2C9;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4;CYP2J2 GO:0006629| lipid metabolic process CYP3A4;PTGS2;CYP2C9;PLA2G2E 14555:[DB04833 DB00735] DB04833|Methaqualone CYP3A4 DB00735|Naftifine SQLE common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SQLE 14556:[DB04833 DB00770] DB04833|Methaqualone CYP3A4 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ABCC4 14557:[DB04833 DB05956] DB04833|Methaqualone CYP3A4 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways 14558:[DB04833 DB09256] DB04833|Methaqualone CYP3A4 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0002933| CYP3A5;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8;CYP3A5 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP2A6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2A6;CYP2E1;CYP3A4;CYP2C8;CYP3A5 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP2C8;CYP3A5;CYP1A2;CYP2A6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C8;CYP3A5 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0042737| drug catabolic process CYP3A5;CYP1A2;CYP3A4 14559:[DB04833 DB04967] DB04833|Methaqualone CYP3A4 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;APEX1 14560:[DB04833 DB07422] DB04833|Methaqualone CYP3A4 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways 14561:[DB04833 DB06094] DB04833|Methaqualone CYP3A4 DB06094|Apatorsen HSPB1 common genes common pathways 14562:[DB04833 DB05390] DB04833|Methaqualone CYP3A4 DB05390|INS 316 P2RY2 common genes common pathways 14563:[DB04833 DB04974] DB04833|Methaqualone CYP3A4 DB04974|AP1903 MTOR common genes common pathways 14564:[DB04833 DB00417] DB04833|Methaqualone CYP3A4 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 14565:[DB04833 DB11691] DB04833|Methaqualone CYP3A4 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes CYP3A4 common pathways GO:0017144| drug metabolic process UGT1A3;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP3A5 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP3A4;CYP3A7 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A7;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 14566:[DB04833 DB04471] DB04833|Methaqualone CYP3A4 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 14567:[DB04833 DB06885] DB04833|Methaqualone CYP3A4 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways 14568:[DB04833 DB02263] DB04833|Methaqualone CYP3A4 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways 14569:[DB04833 DB06311] DB04833|Methaqualone CYP3A4 DB06311|Darapladib PLA2G4A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G4A 14570:[DB04833 DB02696] DB04833|Methaqualone CYP3A4 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways 14571:[DB04833 DB08121] DB04833|Methaqualone CYP3A4 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 14572:[DB04833 DB03192] DB04833|Methaqualone CYP3A4 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways GO:0008209| androgen metabolic process HSD17B4;CYP3A4 GO:0055114| oxidation-reduction process HSD17B4;CYP3A4 GO:0006629| lipid metabolic process HSD17B4;CYP3A4 14573:[DB04833 DB14515] DB04833|Methaqualone CYP3A4 DB14515|Magnesium lactate ATP1A1 common genes common pathways 14574:[DB04833 DB06985] DB04833|Methaqualone CYP3A4 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways 14575:[DB04833 DB03267] DB04833|Methaqualone CYP3A4 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0006629| lipid metabolic process PCK1;CYP3A4 14576:[DB04833 DB00738] DB04833|Methaqualone CYP3A4 DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP3A5 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP1A1;CYP3A4;CYP4A11 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C19;CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0002933| CYP1A1;CYP2C8;CYP3A5;CYP3A4 14577:[DB04833 DB12569] DB04833|Methaqualone CYP3A4 DB12569|Tonapofylline ADORA1 common genes common pathways 14578:[DB04833 DB00882] DB04833|Methaqualone CYP3A4 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP11A1;CYP3A4;CYP2E1;CYP1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2E1;CYP1A2 GO:0002933| CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP11A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0006629| lipid metabolic process CYP11A1;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP11A1;CYP19A1;CYP1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 14579:[DB04833 DB07234] DB04833|Methaqualone CYP3A4 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways 14580:[DB04833 DB05284] DB04833|Methaqualone CYP3A4 DB05284|CA4P TUBB common genes common pathways 14581:[DB04833 DB08498] DB04833|Methaqualone CYP3A4 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways 14582:[DB04833 DB01969] DB04833|Methaqualone CYP3A4 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 14583:[DB04833 DB00172] DB04833|Methaqualone CYP3A4 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process PRODH;P3H1;P4HA1;PYCR2;P4HA2;P3H2;PYCR1;CYP3A4;P3H3 14584:[DB04833 DB01989] DB04833|Methaqualone CYP3A4 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways 14585:[DB04833 DB00269] DB04833|Methaqualone CYP3A4 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 14586:[DB04833 DB02419] DB04833|Methaqualone CYP3A4 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways 14587:[DB04833 DB12128] DB04833|Methaqualone CYP3A4 DB12128|Ulimorelin GHSR common genes common pathways 14588:[DB04833 DB07405] DB04833|Methaqualone CYP3A4 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 14589:[DB04833 DB08746] DB04833|Methaqualone CYP3A4 DB08746|1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE F10 common genes common pathways 14590:[DB04833 DB00711] DB04833|Methaqualone CYP3A4 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ALOX5;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 14591:[DB04833 DB05420] DB04833|Methaqualone CYP3A4 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0055114| oxidation-reduction process RRM1;CYP3A4 14592:[DB04833 DB03187] DB04833|Methaqualone CYP3A4 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 14593:[DB04833 DB05798] DB04833|Methaqualone CYP3A4 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways 14594:[DB04833 DB07733] DB04833|Methaqualone CYP3A4 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways 14595:[DB04833 DB14012] DB04833|Methaqualone CYP3A4 DB14012|Burosumab FGF23 common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;FGF23 14596:[DB04833 DB07978] DB04833|Methaqualone CYP3A4 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 14597:[DB04833 DB08735] DB04833|Methaqualone CYP3A4 DB08735|R,S-Warfarin alcohol ALB common genes common pathways 14598:[DB04833 DB05025] DB04833|Methaqualone CYP3A4 DB05025|Arimoclomol SOD1 common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4 14599:[DB04833 DB06824] DB04833|Methaqualone CYP3A4 DB06824|Triethylenetetramine GPC1 common genes common pathways 14600:[DB04833 DB06245] DB04833|Methaqualone CYP3A4 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;LRP1 14601:[DB04833 DB05424] DB04833|Methaqualone CYP3A4 DB05424|Canertinib EGFR common genes common pathways 14602:[DB04833 DB05219] DB04833|Methaqualone CYP3A4 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes common pathways GO:0002933| CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2B6;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2B6;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2B6;CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2C9;CYP2B6 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 14603:[DB04833 DB00890] DB04833|Methaqualone CYP3A4 DB00890|Dienestrol ESR1;SHBG common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 14604:[DB04833 DB05469] DB04833|Methaqualone CYP3A4 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways 14605:[DB04833 DB00991] DB04833|Methaqualone CYP3A4 DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 14606:[DB04833 DB03003] DB04833|Methaqualone CYP3A4 DB03003|Glutathione Sulfonic Acid gstA;GSTM4;GSTA1;GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1 14607:[DB04833 DB02750] DB04833|Methaqualone CYP3A4 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 14608:[DB04833 DB11638] DB04833|Methaqualone CYP3A4 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0017144| drug metabolic process UGT1A9;CYP2D6;CYP2C19;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;FTO;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A4;UGT2B7 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process G6PD;CYP2D6;CYP3A4;UGT2B7 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C19;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0055114| oxidation-reduction process LDHA;FTO;GAPDHS;LDHB;PRDX1;G6PD;CYP2C19;ALDH7A1;CYP2D6;P4HB;MDH1;GAPDH;CYP3A4;CYCS GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP3A4 14609:[DB04833 DB01161] DB04833|Methaqualone CYP3A4 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways 14610:[DB04833 DB07374] DB04833|Methaqualone CYP3A4 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways 14611:[DB04833 DB04882] DB04833|Methaqualone CYP3A4 DB04882|Edotecarin TOP1 common genes common pathways 14612:[DB04833 DB14637] DB04833|Methaqualone CYP3A4 DB14637|Fluprednisolone acetate CYP3A4 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 14613:[DB04833 DB06451] DB04833|Methaqualone CYP3A4 DB06451|Aprinocarsen PRKCA common genes common pathways 14614:[DB04833 DB07207] DB04833|Methaqualone CYP3A4 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways 14615:[DB04833 DB00663] DB04833|Methaqualone CYP3A4 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 14616:[DB04833 DB01282] DB04833|Methaqualone CYP3A4 DB01282|Carbetocin OXTR common genes common pathways 14617:[DB04833 DB01143] DB04833|Methaqualone CYP3A4 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways 14618:[DB04833 DB02715] DB04833|Methaqualone CYP3A4 DB02715|Compound 18 ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 14619:[DB04833 DB00226] DB04833|Methaqualone CYP3A4 DB00226|Guanadrel SLC6A2 common genes common pathways 14620:[DB04833 DB01373] DB04833|Methaqualone CYP3A4 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0055114| oxidation-reduction process AOC1;CP;CYP3A4 GO:0006805| xenobiotic metabolic process AOC1;CYP3A4 14621:[DB04833 DB00631] DB04833|Methaqualone CYP3A4 DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;RRM1 14622:[DB04833 DB08361] DB04833|Methaqualone CYP3A4 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways 14623:[DB04833 DB11136] DB04833|Methaqualone CYP3A4 DB11136|Chromium CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYB5A;CYP3A4 14624:[DB04833 DB07159] DB04833|Methaqualone CYP3A4 DB07159|Tamatinib SYK common genes common pathways 14625:[DB04833 DB09209] DB04833|Methaqualone CYP3A4 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways 14626:[DB04833 DB00114] DB04833|Methaqualone CYP3A4 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0055114| oxidation-reduction process GLDC;CBS;PNPO;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;SGPL1 GO:0006629| lipid metabolic process SPTLC2;CYP3A4;SGPL1;SPTLC1;SPTLC3 14627:[DB04833 DB02931] DB04833|Methaqualone CYP3A4 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways 14628:[DB04833 DB05513] DB04833|Methaqualone CYP3A4 DB05513|Atiprimod IL6;TNF common genes common pathways 14629:[DB04833 DB11091] DB04833|Methaqualone CYP3A4 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0055114| oxidation-reduction process CAT;GPX1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;GPX1 14630:[DB04833 DB13153] DB04833|Methaqualone CYP3A4 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways 14631:[DB04833 DB08340] DB04833|Methaqualone CYP3A4 DB08340|N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE CSNK2A1 common genes common pathways 14632:[DB04833 DB11640] DB04833|Methaqualone CYP3A4 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0006805| xenobiotic metabolic process NAT1;NAT2;CYP3A4 14633:[DB04833 DB02860] DB04833|Methaqualone CYP3A4 DB02860|Calyculin A PPP1CC common genes common pathways 14634:[DB04833 DB03193] DB04833|Methaqualone CYP3A4 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARA;PLA2G2D 14635:[DB04833 DB00795] DB04833|Methaqualone CYP3A4 DB00795|Sulfasalazine ALOX5;PTGS2;PTGS1;PPARG;CHUK;IKBKB;SLC7A11;ACAT1;TBXAS1;PLA2G1B;ABCG2;ABCC2;SLC46A1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0006629| lipid metabolic process PPARG;TBXAS1;PLA2G1B;CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process TBXAS1;ALOX5;PTGS1;PTGS2;CYP3A4 14636:[DB04833 DB11569] DB04833|Methaqualone CYP3A4 DB11569|Ixekizumab IL17A common genes common pathways 14637:[DB04833 DB06345] DB04833|Methaqualone CYP3A4 DB06345|AR-9281 EPHX2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;EPHX2 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2 14638:[DB04833 DB01130] DB04833|Methaqualone CYP3A4 DB01130|Prednicarbate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 14639:[DB04833 DB06151] DB04833|Methaqualone CYP3A4 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;ACY1 14640:[DB04833 DB03704] DB04833|Methaqualone CYP3A4 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0055114| oxidation-reduction process ADH5;CYP3A4 14641:[DB04833 DB06634] DB04833|Methaqualone CYP3A4 DB06634|Casopitant CYP3A4;TACR1 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 14642:[DB04833 DB05024] DB04833|Methaqualone CYP3A4 DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;CYP24A1 GO:0055114| oxidation-reduction process CYP3A4;CYP24A1 14643:[DB04833 DB09488] DB04833|Methaqualone CYP3A4 DB09488|Acrivastine HRH1 common genes common pathways 14644:[DB04833 DB08869] DB04833|Methaqualone CYP3A4 DB08869|Tesamorelin GHRHR common genes common pathways 14645:[DB04833 DB07465] DB04833|Methaqualone CYP3A4 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways 14646:[DB04833 DB03507] DB04833|Methaqualone CYP3A4 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways 14647:[DB04833 DB05869] DB04833|Methaqualone CYP3A4 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways 14648:[DB04833 DB01629] DB04833|Methaqualone CYP3A4 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1 14649:[DB04833 DB02936] DB04833|Methaqualone CYP3A4 DB02936|4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 14650:[DB04833 DB01021] DB04833|Methaqualone CYP3A4 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways 14651:[DB04833 DB00824] DB04833|Methaqualone CYP3A4 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways 14652:[DB04833 DB11834] DB04833|Methaqualone CYP3A4 DB11834|Guselkumab IL23A common genes common pathways 14653:[DB04833 DB02546] DB04833|Methaqualone CYP3A4 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways 14654:[DB04833 DB00848] DB04833|Methaqualone CYP3A4 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways 14655:[DB04833 DB04947] DB04833|Methaqualone CYP3A4 DB04947|Altropane SLC6A3 common genes common pathways 14656:[DB04833 DB01860] DB04833|Methaqualone CYP3A4 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 14657:[DB04833 DB02917] DB04833|Methaqualone CYP3A4 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways 14658:[DB04833 DB11124] DB04833|Methaqualone CYP3A4 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways 14659:[DB04833 DB02226] DB04833|Methaqualone CYP3A4 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 14660:[DB04833 DB09018] DB04833|Methaqualone CYP3A4 DB09018|Bromopride DRD2 common genes common pathways 14661:[DB04833 DB01096] DB04833|Methaqualone CYP3A4 DB01096|Oxamniquine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 14662:[DB04833 DB05990] DB04833|Methaqualone CYP3A4 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;BAAT;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 14663:[DB04833 DB06061] DB04833|Methaqualone CYP3A4 DB06061|AZD-8330 MAP3K1 common genes common pathways 14664:[DB04833 DB05797] DB04833|Methaqualone CYP3A4 DB05797|TNX-901 FCER1A common genes common pathways 14665:[DB04833 DB07402] DB04833|Methaqualone CYP3A4 DB07402|Azapropazone ALB common genes common pathways 14666:[DB04833 DB04700] DB04833|Methaqualone CYP3A4 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways GO:0055114| oxidation-reduction process GSTK1;CYP3A4 14667:[DB04833 DB04593] DB04833|Methaqualone CYP3A4 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways 14668:[DB04833 DB02209] DB04833|Methaqualone CYP3A4 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0055114| oxidation-reduction process PNPO;CYP3A4 14669:[DB04833 DB05088] DB04833|Methaqualone CYP3A4 DB05088|Tiomolibdate ion APP common genes common pathways 14670:[DB04833 DB08590] DB04833|Methaqualone CYP3A4 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways 14671:[DB04833 DB05749] DB04833|Methaqualone CYP3A4 DB05749|MPI-674 CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 14672:[DB04833 DB09363] DB04833|Methaqualone CYP3A4 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;MAOB 14673:[DB04833 DB01256] DB04833|Methaqualone CYP3A4 DB01256|Retapamulin rplC;CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 14674:[DB04833 DB04345] DB04833|Methaqualone CYP3A4 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;BLVRB 14675:[DB04833 DB13192] DB04833|Methaqualone CYP3A4 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways 14676:[DB04833 DB00211] DB04833|Methaqualone CYP3A4 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 14677:[DB04833 DB01564] DB04833|Methaqualone CYP3A4 DB01564|Calusterone AR common genes common pathways 14678:[DB04833 DB01324] DB04833|Methaqualone CYP3A4 DB01324|Polythiazide SLC12A3 common genes common pathways 14679:[DB04833 DB03058] DB04833|Methaqualone CYP3A4 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways 14680:[DB04833 DB05005] DB04833|Methaqualone CYP3A4 DB05005|CCX282 CCR9 common genes common pathways 14681:[DB04833 DB08008] DB04833|Methaqualone CYP3A4 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 14682:[DB04833 DB01754] DB04833|Methaqualone CYP3A4 DB01754|3,4-Dihydroxy-1-Methylquinolin-2(1h)-One PIM1 common genes common pathways 14683:[DB04833 DB03686] DB04833|Methaqualone CYP3A4 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1 14684:[DB04833 DB03309] DB04833|Methaqualone CYP3A4 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;SULT2B1 GO:0006629| lipid metabolic process SULT2B1;CYP3A4 14685:[DB04833 DB08118] DB04833|Methaqualone CYP3A4 DB08118|2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 14686:[DB04833 DB04003] DB04833|Methaqualone CYP3A4 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways 14687:[DB04833 DB04767] DB04833|Methaqualone CYP3A4 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways 14688:[DB04833 DB11127] DB04833|Methaqualone CYP3A4 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0055114| oxidation-reduction process GPX1;TXNRD1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;GPX1 14689:[DB04833 DB09204] DB04833|Methaqualone CYP3A4 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 14690:[DB04833 DB08826] DB04833|Methaqualone CYP3A4 DB08826|Deferiprone UGT1A6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A6 GO:0006805| xenobiotic metabolic process UGT1A6;CYP3A4 14691:[DB04833 DB08588] DB04833|Methaqualone CYP3A4 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways 14692:[DB04833 DB01205] DB04833|Methaqualone CYP3A4 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways 14693:[DB04833 DB08504] DB04833|Methaqualone CYP3A4 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways 14694:[DB04833 DB03696] DB04833|Methaqualone CYP3A4 DB03696|Lanosterol LSS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;LSS 14695:[DB04833 DB06013] DB04833|Methaqualone CYP3A4 DB06013|Aldoxorubicin TOP2A common genes common pathways 14696:[DB04833 DB05968] DB04833|Methaqualone CYP3A4 DB05968|PR-104 TNF common genes common pathways 14697:[DB04833 DB14004] DB04833|Methaqualone CYP3A4 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP4A11 14698:[DB04833 DB09148] DB04833|Methaqualone CYP3A4 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0017144| drug metabolic process CYP4F2;CYP3A4 GO:0055114| oxidation-reduction process CYP4F2;CYP3A4;CYP2J2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2J2 14699:[DB04833 DB03167] DB04833|Methaqualone CYP3A4 DB03167|Pentabromophenol TTR common genes common pathways 14700:[DB04833 DB05786] DB04833|Methaqualone CYP3A4 DB05786|Irofulven FUBP1 common genes common pathways 14701:[DB04833 DB00407] DB04833|Methaqualone CYP3A4 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 14702:[DB04833 DB08338] DB04833|Methaqualone CYP3A4 DB08338|19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one CSNK2A1 common genes common pathways 14703:[DB04833 DB00966] DB04833|Methaqualone CYP3A4 DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19 GO:0017144| drug metabolic process CYP2C19;UGT1A3;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19 14704:[DB04833 DB06907] DB04833|Methaqualone CYP3A4 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways 14705:[DB04833 DB04217] DB04833|Methaqualone CYP3A4 DB04217|L-2-amino-3-butynoic acid CTH;sufS common genes common pathways 14706:[DB04833 DB05014] DB04833|Methaqualone CYP3A4 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways 14707:[DB04833 DB11590] DB04833|Methaqualone CYP3A4 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;GPX1 GO:0055114| oxidation-reduction process SOD2;GSR;CYP3A4;GPX1 14708:[DB04833 DB06481] DB04833|Methaqualone CYP3A4 DB06481|Manitimus DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 14709:[DB04833 DB07015] DB04833|Methaqualone CYP3A4 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways 14710:[DB04833 DB00167] DB04833|Methaqualone CYP3A4 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ACADSB GO:0055114| oxidation-reduction process ACADSB;CYP3A4 14711:[DB04833 DB02459] DB04833|Methaqualone CYP3A4 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways 14712:[DB04833 DB02638] DB04833|Methaqualone CYP3A4 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways 14713:[DB04833 DB05159] DB04833|Methaqualone CYP3A4 DB05159|CCX915 CCR2 common genes common pathways 14714:[DB04833 DB06069] DB04833|Methaqualone CYP3A4 DB06069|XMT-1001 TOP1 common genes common pathways 14715:[DB04833 DB02074] DB04833|Methaqualone CYP3A4 DB02074|Butenoic Acid FABP1 common genes common pathways 14716:[DB04833 DB14033] DB04833|Methaqualone CYP3A4 DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 14717:[DB04833 DB05712] DB04833|Methaqualone CYP3A4 DB05712|AZD-9684 CPB2 common genes common pathways 14718:[DB04833 DB00467] DB04833|Methaqualone CYP3A4 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 14719:[DB04833 DB08837] DB04833|Methaqualone CYP3A4 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways 14720:[DB04833 DB00187] DB04833|Methaqualone CYP3A4 DB00187|Esmolol ADRB1;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 14721:[DB04833 DB03336] DB04833|Methaqualone CYP3A4 DB03336|BIA COMT common genes common pathways 14722:[DB04833 DB06817] DB04833|Methaqualone CYP3A4 DB06817|Raltegravir pol;UGT1A1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 14723:[DB04833 DB04715] DB04833|Methaqualone CYP3A4 DB04715|IMIDAZOPYRIDAZIN 1 PIM1 common genes common pathways 14724:[DB04833 DB06892] DB04833|Methaqualone CYP3A4 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways 14725:[DB04833 DB05553] DB04833|Methaqualone CYP3A4 DB05553|Regrelor P2RY12 common genes common pathways 14726:[DB04833 DB00013] DB04833|Methaqualone CYP3A4 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0006629| lipid metabolic process LRP2;CYP3A4 GO:0042359| vitamin D metabolic process LRP2;CYP3A4 14727:[DB04833 DB08672] DB04833|Methaqualone CYP3A4 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways 14728:[DB04833 DB01863] DB04833|Methaqualone CYP3A4 DB01863|Inositol 1,3,4,5-Tetrakisphosphate AKT1;PLEKHA4;BTK;DAPP1;ITPKA;CYTH2;CYTH3;PDPK1 common genes common pathways 14729:[DB04833 DB07176] DB04833|Methaqualone CYP3A4 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways 14730:[DB04833 DB04648] DB04833|Methaqualone CYP3A4 DB04648|S-propylamine-L-cysteine ARG1 common genes common pathways 14731:[DB04833 DB00137] DB04833|Methaqualone CYP3A4 DB00137|Lutein ALB common genes common pathways 14732:[DB04833 DB01345] DB04833|Methaqualone CYP3A4 DB01345|Potassium cation ATP1A1 common genes common pathways 14733:[DB04833 DB11338] DB04833|Methaqualone CYP3A4 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;VCAM1 14734:[DB04833 DB00505] DB04833|Methaqualone CYP3A4 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways 14735:[DB04833 DB09499] DB04833|Methaqualone CYP3A4 DB09499|Thiosulfuric acid TST common genes common pathways 14736:[DB04833 DB00166] DB04833|Methaqualone CYP3A4 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;POR GO:0006629| lipid metabolic process CYP3A4;LIPT1 GO:0006805| xenobiotic metabolic process POR;CYP3A4 14737:[DB04833 DB04149] DB04833|Methaqualone CYP3A4 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways 14738:[DB04833 DB08370] DB04833|Methaqualone CYP3A4 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP3A4 14739:[DB04833 DB06785] DB04833|Methaqualone CYP3A4 DB06785|Ganirelix GNRHR common genes common pathways 14740:[DB04833 DB11235] DB04833|Methaqualone CYP3A4 DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 14741:[DB04833 DB13620] DB04833|Methaqualone CYP3A4 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways 14742:[DB04833 DB01191] DB04833|Methaqualone CYP3A4 DB01191|Dexfenfluramine SLC6A4;HTR2C;CYP2D6;CYP1A2;CYP2E1 common genes common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 14743:[DB04833 DB05137] DB04833|Methaqualone CYP3A4 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways 14744:[DB04833 DB14071] DB04833|Methaqualone CYP3A4 DB14071|Desmethylsertraline ABCB1 common genes common pathways 14745:[DB04833 DB03496] DB04833|Methaqualone CYP3A4 DB03496|Alvocidib CDK2;CDK5;CDK9;CDK1;CDK6;EGFR;CDK4;CDK8;CDK7;PYGM;PYGB;PYGL;UGT1A1;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 14746:[DB04833 DB04459] DB04833|Methaqualone CYP3A4 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways 14747:[DB04833 DB07101] DB04833|Methaqualone CYP3A4 DB07101|PD-0325901 MAP2K1 common genes common pathways 14748:[DB04833 DB04754] DB04833|Methaqualone CYP3A4 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways 14749:[DB04833 DB03695] DB04833|Methaqualone CYP3A4 DB03695|Piritrexim DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 14750:[DB04833 DB00915] DB04833|Methaqualone CYP3A4 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOB 14751:[DB04833 DB02877] DB04833|Methaqualone CYP3A4 DB02877|Arotinoid acid RARB common genes common pathways 14752:[DB04833 DB08454] DB04833|Methaqualone CYP3A4 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways 14753:[DB04833 DB06706] DB04833|Methaqualone CYP3A4 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways 14754:[DB04833 DB00214] DB04833|Methaqualone CYP3A4 DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;PTGS1;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PTGS1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0002933| CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4 14755:[DB04833 DB11792] DB04833|Methaqualone CYP3A4 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP3A5 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;CYP3A7 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP3A7;CYP3A4 14756:[DB04833 DB03856] DB04833|Methaqualone CYP3A4 DB03856|L-Eflornithine ODC1 common genes common pathways 14757:[DB04833 DB01120] DB04833|Methaqualone CYP3A4 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C19 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C19 14758:[DB04833 DB07339] DB04833|Methaqualone CYP3A4 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NQO2 GO:0006805| xenobiotic metabolic process CYP3A4;NQO2 14759:[DB04833 DB06471] DB04833|Methaqualone CYP3A4 DB06471|Naxifylline ADORA1 common genes common pathways 14760:[DB04833 DB06726] DB04833|Methaqualone CYP3A4 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 14761:[DB04833 DB01933] DB04833|Methaqualone CYP3A4 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways 14762:[DB04833 DB03606] DB04833|Methaqualone CYP3A4 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways 14763:[DB04833 DB00244] DB04833|Methaqualone CYP3A4 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0055114| oxidation-reduction process ALOX5;MPO;PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1;PPARG 14764:[DB04833 DB03977] DB04833|Methaqualone CYP3A4 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYCS 14765:[DB04833 DB00070] DB04833|Methaqualone CYP3A4 DB00070|Hyaluronidase TGFB1;ALB common genes common pathways 14766:[DB04833 DB00274] DB04833|Methaqualone CYP3A4 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways 14767:[DB04833 DB06468] DB04833|Methaqualone CYP3A4 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;CYP3A4 14768:[DB04833 DB07638] DB04833|Methaqualone CYP3A4 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 14769:[DB04833 DB06833] DB04833|Methaqualone CYP3A4 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways 14770:[DB04833 DB13932] DB04833|Methaqualone CYP3A4 DB13932|Voretigene Neparvovec RPE65 common genes common pathways GO:0055114| oxidation-reduction process RPE65;CYP3A4 14771:[DB04833 DB06358] DB04833|Methaqualone CYP3A4 DB06358|Iclaprim DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 14772:[DB04833 DB02306] DB04833|Methaqualone CYP3A4 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 14773:[DB04833 DB09276] DB04833|Methaqualone CYP3A4 DB09276|Sodium aurothiomalate UGT1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 14774:[DB04833 DB00689] DB04833|Methaqualone CYP3A4 DB00689|Cephaloglycin SLC22A5 common genes common pathways 14775:[DB04833 DB08089] DB04833|Methaqualone CYP3A4 DB08089|LGD-2226 AR common genes common pathways 14776:[DB04833 DB01044] DB04833|Methaqualone CYP3A4 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 14777:[DB04833 DB04012] DB04833|Methaqualone CYP3A4 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways 14778:[DB04833 DB02557] DB04833|Methaqualone CYP3A4 DB02557|Phosphoramidon MME;KEL common genes common pathways 14779:[DB04833 DB04281] DB04833|Methaqualone CYP3A4 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 14780:[DB04833 DB05171] DB04833|Methaqualone CYP3A4 DB05171|E-2012 APH1A;PSENEN common genes common pathways 14781:[DB04833 DB00772] DB04833|Methaqualone CYP3A4 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2B6 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP2B6;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP1A2 14782:[DB04833 DB07135] DB04833|Methaqualone CYP3A4 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways 14783:[DB04833 DB07525] DB04833|Methaqualone CYP3A4 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways 14784:[DB04833 DB06993] DB04833|Methaqualone CYP3A4 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways 14785:[DB04833 DB05667] DB04833|Methaqualone CYP3A4 DB05667|Levoketoconazole CYP11B1;CYP51A1 common genes common pathways GO:0055114| oxidation-reduction process CYP11B1;CYP51A1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP51A1;CYP11B1 GO:0008202| steroid metabolic process CYP3A4;CYP11B1;CYP51A1 14786:[DB04833 DB02919] DB04833|Methaqualone CYP3A4 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 14787:[DB04833 DB01131] DB04833|Methaqualone CYP3A4 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0070989| oxidative demethylation CYP3A4;CYP2D6;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;DHFR;CYP2C9;CYP3A4;CYP2E1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C9 14788:[DB04833 DB07141] DB04833|Methaqualone CYP3A4 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 14789:[DB04833 DB00421] DB04833|Methaqualone CYP3A4 DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0008209| androgen metabolic process SRD5A2;CYP3A4;SRD5A1 GO:0055114| oxidation-reduction process CYP2C8;SRD5A1;SRD5A3;SRD5A2;CYP3A4;CYP11B2;CYP11B1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NR1I2 GO:0006629| lipid metabolic process SRD5A3;SRD5A2;CYP3A4;CYP11B1;CYP11B2;SRD5A1 GO:0006706| steroid catabolic process CYP3A4;SRD5A2 GO:0006805| xenobiotic metabolic process CYP3A4;NR1I2;CYP2C8 GO:0002933| CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;NR1I2;SRD5A1;CYP11B1;CYP11B2;SRD5A2;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 14790:[DB04833 DB05078] DB04833|Methaqualone CYP3A4 DB05078|AER001 IL4R;IL13RA2 common genes common pathways 14791:[DB04833 DB00572] DB04833|Methaqualone CYP3A4 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways 14792:[DB04833 DB05332] DB04833|Methaqualone CYP3A4 DB05332|Romiplostim MPL common genes common pathways 14793:[DB04833 DB05339] DB04833|Methaqualone CYP3A4 DB05339|MN-305 HTR1A common genes common pathways 14794:[DB04833 DB00598] DB04833|Methaqualone CYP3A4 DB00598|Labetalol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C19 14795:[DB04833 DB07036] DB04833|Methaqualone CYP3A4 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways 14796:[DB04833 DB00415] DB04833|Methaqualone CYP3A4 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1 14797:[DB04833 DB00110] DB04833|Methaqualone CYP3A4 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 14798:[DB04833 DB01094] DB04833|Methaqualone CYP3A4 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;SOAT1;CYP1A2;SOAT2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process SOAT2;SOAT1;CYP1A2;CYP3A4;MTTP GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 14799:[DB04833 DB05139] DB04833|Methaqualone CYP3A4 DB05139|CR002 PDGFD common genes common pathways 14800:[DB04833 DB11275] DB04833|Methaqualone CYP3A4 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways 14801:[DB04833 DB00650] DB04833|Methaqualone CYP3A4 DB00650|Leucovorin SLC22A8 common genes common pathways 14802:[DB04833 DB04738] DB04833|Methaqualone CYP3A4 DB04738|Motuporin PPP1CC common genes common pathways 14803:[DB04833 DB05001] DB04833|Methaqualone CYP3A4 DB05001|PSN9301 DPP4 common genes common pathways 14804:[DB04833 DB00111] DB04833|Methaqualone CYP3A4 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 14805:[DB04833 DB13933] DB04833|Methaqualone CYP3A4 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0055114| oxidation-reduction process F8;CYP3A4 14806:[DB04833 DB04796] DB04833|Methaqualone CYP3A4 DB04796|Inecalcitol VDR common genes common pathways 14807:[DB04833 DB08574] DB04833|Methaqualone CYP3A4 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 14808:[DB04833 DB07768] DB04833|Methaqualone CYP3A4 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0008202| steroid metabolic process AKR1C2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;AKR1C2 GO:0006805| xenobiotic metabolic process CYP3A4;AKR1C1 GO:0055114| oxidation-reduction process AKR1C2;CYP3A4;AKR1C1 14809:[DB04833 DB01053] DB04833|Methaqualone CYP3A4 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways 14810:[DB04833 DB06830] DB04833|Methaqualone CYP3A4 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 14811:[DB04833 DB03247] DB04833|Methaqualone CYP3A4 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0055114| oxidation-reduction process PNPO;HAO2;DHODH;DPYD;CYP3A4;HAO1;POR;NOS1;BLVRB GO:0042738| exogenous drug catabolic process NOS1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;POR 14812:[DB04833 DB03907] DB04833|Methaqualone CYP3A4 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways 14813:[DB04833 DB06354] DB04833|Methaqualone CYP3A4 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways 14814:[DB04833 DB12773] DB04833|Methaqualone CYP3A4 DB12773|Sifalimumab IFNA2 common genes common pathways 14815:[DB04833 DB04521] DB04833|Methaqualone CYP3A4 DB04521|GSHNA GSTA3 common genes common pathways 14816:[DB04833 DB04756] DB04833|Methaqualone CYP3A4 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways 14817:[DB04833 DB11731] DB04833|Methaqualone CYP3A4 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways 14818:[DB04833 DB04753] DB04833|Methaqualone CYP3A4 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways 14819:[DB04833 DB01033] DB04833|Methaqualone CYP3A4 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;AOX1 GO:0055114| oxidation-reduction process AOX1;IMPDH1;XDH;IMPDH2;CYP3A4;ABCC4 14820:[DB04833 DB02264] DB04833|Methaqualone CYP3A4 DB02264|O2-Sulfo-Glucuronic Acid FGF1;HGF;HS3ST3A1 common genes common pathways 14821:[DB04833 DB05883] DB04833|Methaqualone CYP3A4 DB05883|ABX-PTH PTH common genes common pathways 14822:[DB04833 DB08841] DB04833|Methaqualone CYP3A4 DB08841|Tyramine SLC22A3 common genes common pathways 14823:[DB04833 DB08814] DB04833|Methaqualone CYP3A4 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;NOS2 14824:[DB04833 DB07443] DB04833|Methaqualone CYP3A4 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 14825:[DB04833 DB07032] DB04833|Methaqualone CYP3A4 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways 14826:[DB04833 DB09272] DB04833|Methaqualone CYP3A4 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways 14827:[DB04833 DB00024] DB04833|Methaqualone CYP3A4 DB00024|Thyrotropin alfa TSHR common genes common pathways 14828:[DB04833 DB00657] DB04833|Methaqualone CYP3A4 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways 14829:[DB04833 DB08844] DB04833|Methaqualone CYP3A4 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways 14830:[DB04833 DB09110] DB04833|Methaqualone CYP3A4 DB09110|Coenzyme M GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GSR 14831:[DB04833 DB00810] DB04833|Methaqualone CYP3A4 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 14832:[DB04833 DB08382] DB04833|Methaqualone CYP3A4 DB08382|Gosogliptin DPP4 common genes common pathways 14833:[DB04833 DB09460] DB04833|Methaqualone CYP3A4 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways 14834:[DB04833 DB01405] DB04833|Methaqualone CYP3A4 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 14835:[DB04833 DB02613] DB04833|Methaqualone CYP3A4 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 GO:0006629| lipid metabolic process PNLIPRP2;CYP3A4 14836:[DB04833 DB13873] DB04833|Methaqualone CYP3A4 DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;NR1I2 GO:0006629| lipid metabolic process PPARA;CYP3A4;PPARD;PPARG GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4 GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4 14837:[DB04833 DB05361] DB04833|Methaqualone CYP3A4 DB05361|SR-123781A SERPINC1;F2R common genes common pathways 14838:[DB04833 DB08784] DB04833|Methaqualone CYP3A4 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 14839:[DB04833 DB02285] DB04833|Methaqualone CYP3A4 DB02285|Protoporphyrin FTL common genes common pathways 14840:[DB04833 DB00038] DB04833|Methaqualone CYP3A4 DB00038|Oprelvekin IL11RA common genes common pathways 14841:[DB04833 DB00512] DB04833|Methaqualone CYP3A4 DB00512|Vancomycin ALB;ORM1;ORM2 common genes common pathways 14842:[DB04833 DB06231] DB04833|Methaqualone CYP3A4 DB06231|Caldaret SLC8A1 common genes common pathways 14843:[DB04833 DB00160] DB04833|Methaqualone CYP3A4 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways 14844:[DB04833 DB00596] DB04833|Methaqualone CYP3A4 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways 14845:[DB04833 DB07008] DB04833|Methaqualone CYP3A4 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 14846:[DB04833 DB00094] DB04833|Methaqualone CYP3A4 DB00094|Urofollitropin FSHR common genes common pathways 14847:[DB04833 DB09395] DB04833|Methaqualone CYP3A4 DB09395|Sodium acetate ACSS2 common genes common pathways 14848:[DB04833 DB11639] DB04833|Methaqualone CYP3A4 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways 14849:[DB04833 DB11075] DB04833|Methaqualone CYP3A4 DB11075|Hypromellose EPCAM common genes common pathways 14850:[DB04833 DB01366] DB04833|Methaqualone CYP3A4 DB01366|Procaterol ADRB2 common genes common pathways 14851:[DB04833 DB00385] DB04833|Methaqualone CYP3A4 DB00385|Valrubicin TOP2A common genes common pathways 14852:[DB04833 DB14596] DB04833|Methaqualone CYP3A4 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PON1 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 14853:[DB04833 DB04207] DB04833|Methaqualone CYP3A4 DB04207|N-(5-Amino-5-Carboxypentyl)Glutamic Acid AASS common genes common pathways GO:0055114| oxidation-reduction process AASS;CYP3A4 14854:[DB04833 DB13036] DB04833|Methaqualone CYP3A4 DB13036|Ramatroban PTGDR2 common genes common pathways 14855:[DB04833 DB14530] DB04833|Methaqualone CYP3A4 DB14530|Chromous sulfate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYB5A 14856:[DB04833 DB01144] DB04833|Methaqualone CYP3A4 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 14857:[DB04833 DB00558] DB04833|Methaqualone CYP3A4 DB00558|Zanamivir NEU2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;NEU2 14858:[DB04833 DB00033] DB04833|Methaqualone CYP3A4 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 14859:[DB04833 DB08168] DB04833|Methaqualone CYP3A4 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways 14860:[DB04833 DB13997] DB04833|Methaqualone CYP3A4 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A3 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 14861:[DB04833 DB08044] DB04833|Methaqualone CYP3A4 DB08044|ABT-341 DPP4 common genes common pathways 14862:[DB04833 DB14582] DB04833|Methaqualone CYP3A4 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways 14863:[DB04833 DB00691] DB04833|Methaqualone CYP3A4 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways 14864:[DB04833 DB02322] DB04833|Methaqualone CYP3A4 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways 14865:[DB04833 DB05442] DB04833|Methaqualone CYP3A4 DB05442|Etiprednol dicloacetate IL1B common genes common pathways 14866:[DB04833 DB09060] DB04833|Methaqualone CYP3A4 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways 14867:[DB04833 DB04733] DB04833|Methaqualone CYP3A4 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways 14868:[DB04833 DB04114] DB04833|Methaqualone CYP3A4 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways 14869:[DB04833 DB01599] DB04833|Methaqualone CYP3A4 DB01599|Probucol ABCA1;CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CES1 GO:0006629| lipid metabolic process ABCA1;CYP3A4 GO:0008202| steroid metabolic process ABCA1;CYP3A4 14870:[DB04833 DB09258] DB04833|Methaqualone CYP3A4 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways 14871:[DB04833 DB02485] DB04833|Methaqualone CYP3A4 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 14872:[DB04833 DB05936] DB04833|Methaqualone CYP3A4 DB05936|CVT-6883 ADORA2B common genes common pathways 14873:[DB04833 DB08426] DB04833|Methaqualone CYP3A4 DB08426|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE F10 common genes common pathways 14874:[DB04833 DB03604] DB04833|Methaqualone CYP3A4 DB03604|Tiratricol THRB common genes common pathways 14875:[DB04833 DB01005] DB04833|Methaqualone CYP3A4 DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;RRM1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 14876:[DB04833 DB04672] DB04833|Methaqualone CYP3A4 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways 14877:[DB04833 DB06140] DB04833|Methaqualone CYP3A4 DB06140|SUVN-502 HTR6 common genes common pathways 14878:[DB04833 DB01425] DB04833|Methaqualone CYP3A4 DB01425|Alizapride DRD2 common genes common pathways 14879:[DB04833 DB01057] DB04833|Methaqualone CYP3A4 DB01057|Echothiophate BCHE;ALB common genes common pathways 14880:[DB04833 DB01998] DB04833|Methaqualone CYP3A4 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways 14881:[DB04833 DB13168] DB04833|Methaqualone CYP3A4 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0006629| lipid metabolic process FADS1;FADS2;CYP3A4;PTGS2 GO:0055114| oxidation-reduction process FADS2;FADS1;ALOX5;CYP3A4;PTGS2 14882:[DB04833 DB03066] DB04833|Methaqualone CYP3A4 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 14883:[DB04833 DB11892] DB04833|Methaqualone CYP3A4 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 14884:[DB04833 DB06756] DB04833|Methaqualone CYP3A4 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0055114| oxidation-reduction process PRODH;CYP3A4 14885:[DB04833 DB07389] DB04833|Methaqualone CYP3A4 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 14886:[DB04833 DB00787] DB04833|Methaqualone CYP3A4 DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways 14887:[DB04833 DB09332] DB04833|Methaqualone CYP3A4 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0017144| drug metabolic process CYP3A4;VKORC1 GO:0055114| oxidation-reduction process CYP3A4;VKORC1;POR GO:0006805| xenobiotic metabolic process POR;CYP3A4 14888:[DB04833 DB02596] DB04833|Methaqualone CYP3A4 DB02596|Alpha,Beta-Methyleneadenosine-5'-Triphosphate folK;panC;nadE;NMNAT3;carA common genes common pathways 14889:[DB04833 DB00029] DB04833|Methaqualone CYP3A4 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 14890:[DB04833 DB08051] DB04833|Methaqualone CYP3A4 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways 14891:[DB04833 DB08127] DB04833|Methaqualone CYP3A4 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways 14892:[DB04833 DB03023] DB04833|Methaqualone CYP3A4 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways 14893:[DB04833 DB00550] DB04833|Methaqualone CYP3A4 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0055114| oxidation-reduction process DBH;MPO;CYP3A4;CYP1A1;TPO GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0002933| CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A1 14894:[DB04833 DB03344] DB04833|Methaqualone CYP3A4 DB03344|Inositol-(1,3,4,5,6)-Pentakisphosphate CYTH3 common genes common pathways 14895:[DB04833 DB05130] DB04833|Methaqualone CYP3A4 DB05130|INCB3284 CCR2 common genes common pathways 14896:[DB04833 DB09052] DB04833|Methaqualone CYP3A4 DB09052|Blinatumomab CD19;CD3D common genes common pathways 14897:[DB04833 DB08834] DB04833|Methaqualone CYP3A4 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways 14898:[DB04833 DB07843] DB04833|Methaqualone CYP3A4 DB07843|5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways 14899:[DB04833 DB03153] DB04833|Methaqualone CYP3A4 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 14900:[DB04833 DB12651] DB04833|Methaqualone CYP3A4 DB12651|Bardoxolone CASP8 common genes common pathways 14901:[DB04833 DB00698] DB04833|Methaqualone CYP3A4 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;POR GO:0055114| oxidation-reduction process CYP3A4;POR 14902:[DB04833 DB00145] DB04833|Methaqualone CYP3A4 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0006629| lipid metabolic process BAAT;CYP3A4 GO:0006805| xenobiotic metabolic process GLYAT;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PIPOX;GLDC 14903:[DB04833 DB04410] DB04833|Methaqualone CYP3A4 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways 14904:[DB04833 DB00830] DB04833|Methaqualone CYP3A4 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways 14905:[DB04833 DB14017] DB04833|Methaqualone CYP3A4 DB14017|H3B-8800 SF3B1 common genes common pathways 14906:[DB04833 DB00052] DB04833|Methaqualone CYP3A4 DB00052|Somatotropin GHR;PRLR common genes common pathways 14907:[DB04833 DB05967] DB04833|Methaqualone CYP3A4 DB05967|ANZ-100 KISS1R common genes common pathways 14908:[DB04833 DB12243] DB04833|Methaqualone CYP3A4 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways 14909:[DB04833 DB05448] DB04833|Methaqualone CYP3A4 DB05448|PX-12 TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TXNRD1 14910:[DB04833 DB07151] DB04833|Methaqualone CYP3A4 DB07151|4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one PIM1 common genes common pathways 14911:[DB04833 DB11830] DB04833|Methaqualone CYP3A4 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways 14912:[DB04833 DB05532] DB04833|Methaqualone CYP3A4 DB05532|BMS-488043 FFAR4 common genes common pathways 14913:[DB04833 DB05449] DB04833|Methaqualone CYP3A4 DB05449|FM-VP4 ABCB1 common genes common pathways 14914:[DB04833 DB07180] DB04833|Methaqualone CYP3A4 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways 14915:[DB04833 DB09348] DB04833|Methaqualone CYP3A4 DB09348|Propiolactone ALB common genes common pathways 14916:[DB04833 DB14001] DB04833|Methaqualone CYP3A4 DB14001|alpha-Tocopherol succinate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0008202| steroid metabolic process NR1I2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1;NQO1;NR1I2 GO:0006629| lipid metabolic process CYP3A4;TTPA GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2 GO:0055114| oxidation-reduction process CYP3A4;GSTO1;HMOX1;SOD1;ALOX5;NQO1 14917:[DB04833 DB04988] DB04833|Methaqualone CYP3A4 DB04988|IGN311 EGFR;ERBB2 common genes common pathways 14918:[DB04833 DB08058] DB04833|Methaqualone CYP3A4 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 14919:[DB04833 DB09539] DB04833|Methaqualone CYP3A4 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways GO:0008202| steroid metabolic process SOAT1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;SOAT1 14920:[DB04833 DB03953] DB04833|Methaqualone CYP3A4 DB03953|L-Thiocitrulline NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 14921:[DB04833 DB06733] DB04833|Methaqualone CYP3A4 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 14922:[DB04833 DB02933] DB04833|Methaqualone CYP3A4 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 14923:[DB04833 DB02056] DB04833|Methaqualone CYP3A4 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;AKR1C3 GO:0008202| steroid metabolic process AKR1C3;CYP3A4 14924:[DB04833 DB01294] DB04833|Methaqualone CYP3A4 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 14925:[DB04833 DB04665] DB04833|Methaqualone CYP3A4 DB04665|Coumarin CYP2A6;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2A6;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2A6 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2C9 14926:[DB04833 DB06643] DB04833|Methaqualone CYP3A4 DB06643|Denosumab TNFSF11 common genes common pathways 14927:[DB04833 DB04723] DB04833|Methaqualone CYP3A4 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways 14928:[DB04833 DB00105] DB04833|Methaqualone CYP3A4 DB00105|Interferon Alfa-2b, Recombinant IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 14929:[DB04833 DB02565] DB04833|Methaqualone CYP3A4 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways 14930:[DB04833 DB01022] DB04833|Methaqualone CYP3A4 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 14931:[DB04833 DB03166] DB04833|Methaqualone CYP3A4 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 14932:[DB04833 DB07616] DB04833|Methaqualone CYP3A4 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 14933:[DB04833 DB07136] DB04833|Methaqualone CYP3A4 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 14934:[DB04833 DB04576] DB04833|Methaqualone CYP3A4 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 14935:[DB04833 DB02337] DB04833|Methaqualone CYP3A4 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 14936:[DB04833 DB14641] DB04833|Methaqualone CYP3A4 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 14937:[DB04833 DB00116] DB04833|Methaqualone CYP3A4 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process MTHFR;CYP3A4;MTHFD2;MTHFD1;ALDH1L1 14938:[DB04833 DB02158] DB04833|Methaqualone CYP3A4 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 14939:[DB04833 DB00767] DB04833|Methaqualone CYP3A4 DB00767|Benzquinamide HRH1;CHRM4;CHRM1;CHRM5;CHRM2;CHRM3 common genes common pathways 14940:[DB04833 DB05033] DB04833|Methaqualone CYP3A4 DB05033|INCB7839 ADAM9 common genes common pathways 14941:[DB04833 DB13998] DB04833|Methaqualone CYP3A4 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0055114| oxidation-reduction process PHYH;CYP3A4 GO:0006629| lipid metabolic process LRP1;CYP3A4 14942:[DB04833 DB08835] DB04833|Methaqualone CYP3A4 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways 14943:[DB04833 DB05460] DB04833|Methaqualone CYP3A4 DB05460|Ezatiostat GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1 14944:[DB04833 DB03288] DB04833|Methaqualone CYP3A4 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways 14945:[DB04833 DB05299] DB04833|Methaqualone CYP3A4 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways 14946:[DB04833 DB04877] DB04833|Methaqualone CYP3A4 DB04877|Voacamine ABCB1 common genes common pathways 14947:[DB04833 DB02105] DB04833|Methaqualone CYP3A4 DB02105|3,5-Dinitrocatechol COMT common genes common pathways 14948:[DB04833 DB04960] DB04833|Methaqualone CYP3A4 DB04960|Tipifarnib FNTB common genes common pathways 14949:[DB04833 DB03203] DB04833|Methaqualone CYP3A4 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways 14950:[DB04833 DB13988] DB04833|Methaqualone CYP3A4 DB13988|SB-269970 HTR7 common genes common pathways 14951:[DB04833 DB07358] DB04833|Methaqualone CYP3A4 DB07358|2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 14952:[DB04833 DB11726] DB04833|Methaqualone CYP3A4 DB11726|Encenicline CHRNA7 common genes common pathways 14953:[DB04833 DB07841] DB04833|Methaqualone CYP3A4 DB07841|Geranylgeranyl diphosphate FNTA;PGGT1B;FNTB;GGPS1;FDPS;RABGGTA;RABGGTB common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 14954:[DB04833 DB04657] DB04833|Methaqualone CYP3A4 DB04657|Carboxin SDHA common genes common pathways GO:0055114| oxidation-reduction process SDHA;CYP3A4 14955:[DB04833 DB00779] DB04833|Methaqualone CYP3A4 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process TDO2;CYP3A4 14956:[DB04833 DB01086] DB04833|Methaqualone CYP3A4 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP3A4 14957:[DB04833 DB00858] DB04833|Methaqualone CYP3A4 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1 14958:[DB04833 DB01562] DB04833|Methaqualone CYP3A4 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 14959:[DB04833 DB08363] DB04833|Methaqualone CYP3A4 DB08363|1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine TP53 common genes common pathways 14960:[DB04833 DB02853] DB04833|Methaqualone CYP3A4 DB02853|D-Proline SLC36A1 common genes common pathways 14961:[DB04833 DB04275] DB04833|Methaqualone CYP3A4 DB04275|N-acetylserotonin SPR common genes common pathways GO:0055114| oxidation-reduction process SPR;CYP3A4 14962:[DB04833 DB00016] DB04833|Methaqualone CYP3A4 DB00016|Erythropoietin EPOR common genes common pathways 14963:[DB04833 DB06704] DB04833|Methaqualone CYP3A4 DB06704|Iobenguane SLC6A2 common genes common pathways 14964:[DB04833 DB06226] DB04833|Methaqualone CYP3A4 DB06226|Nelipepimut-S HLA-A;HLA-A common genes common pathways 14965:[DB04833 DB03121] DB04833|Methaqualone CYP3A4 DB03121|(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 14966:[DB04833 DB07757] DB04833|Methaqualone CYP3A4 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways 14967:[DB04833 DB09322] DB04833|Methaqualone CYP3A4 DB09322|Zinc sulfate ALPPL2 common genes common pathways 14968:[DB04833 DB08553] DB04833|Methaqualone CYP3A4 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways 14969:[DB04833 DB07544] DB04833|Methaqualone CYP3A4 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways 14970:[DB04833 DB00142] DB04833|Methaqualone CYP3A4 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0055114| oxidation-reduction process AASS;ALDH18A1;CYP3A4;GLUD1;GLUD2 14971:[DB04833 DB07444] DB04833|Methaqualone CYP3A4 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways 14972:[DB04833 DB11842] DB04833|Methaqualone CYP3A4 DB11842|Angiotensin II AGTR1 common genes common pathways 14973:[DB04833 DB13173] DB04833|Methaqualone CYP3A4 DB13173|Cerliponase alfa IGF2R common genes common pathways 14974:[DB04833 DB06680] DB04833|Methaqualone CYP3A4 DB06680|Asoprisnil PGR common genes common pathways 14975:[DB04833 DB05120] DB04833|Methaqualone CYP3A4 DB05120|AT1391 INSR common genes common pathways 14976:[DB04833 DB09207] DB04833|Methaqualone CYP3A4 DB09207|AS-8112 DRD2;DRD3 common genes common pathways 14977:[DB04833 DB04094] DB04833|Methaqualone CYP3A4 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways 14978:[DB04833 DB04719] DB04833|Methaqualone CYP3A4 DB04719|DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE CSNK2A1 common genes common pathways 14979:[DB04833 DB00198] DB04833|Methaqualone CYP3A4 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process NEU1;NEU2;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;ABCC4 14980:[DB04833 DB08871] DB04833|Methaqualone CYP3A4 DB08871|Eribulin BCL2;TUBB1 common genes common pathways 14981:[DB04833 DB04462] DB04833|Methaqualone CYP3A4 DB04462|Tetrabromo-2-Benzotriazole CSNK2A1 common genes common pathways 14982:[DB04833 DB05996] DB04833|Methaqualone CYP3A4 DB05996|Glembatumumab vedotin GPNMB common genes common pathways 14983:[DB04833 DB04197] DB04833|Methaqualone CYP3A4 DB04197|Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways 14984:[DB04833 DB05915] DB04833|Methaqualone CYP3A4 DB05915|MYO-029 MSTN common genes common pathways 14985:[DB04833 DB07981] DB04833|Methaqualone CYP3A4 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4 14986:[DB04833 DB09285] DB04833|Methaqualone CYP3A4 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process ALOX5;CYP3A4;PTGS2 14987:[DB04833 DB03048] DB04833|Methaqualone CYP3A4 DB03048|6-Carboxymethyluracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP3A4 14988:[DB04833 DB01106] DB04833|Methaqualone CYP3A4 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways 14989:[DB04833 DB01210] DB04833|Methaqualone CYP3A4 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 14990:[DB04833 DB02556] DB04833|Methaqualone CYP3A4 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CRH 14991:[DB04833 DB06217] DB04833|Methaqualone CYP3A4 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 14992:[DB04833 DB02570] DB04833|Methaqualone CYP3A4 DB02570|PD150606 CAPNS1 common genes common pathways 14993:[DB04833 DB07960] DB04833|Methaqualone CYP3A4 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways GO:0006629| lipid metabolic process NEU2;CYP3A4 14994:[DB04833 DB02266] DB04833|Methaqualone CYP3A4 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;PPARA;PTGS1;PPARG GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process PTGS1;AKR1C3;PTGS2;CYP3A4 GO:0008202| steroid metabolic process AKR1C3;CYP3A4 14995:[DB04833 DB02377] DB04833|Methaqualone CYP3A4 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways 14996:[DB04833 DB12305] DB04833|Methaqualone CYP3A4 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways 14997:[DB04833 DB01619] DB04833|Methaqualone CYP3A4 DB01619|Phenindamine HRH1 common genes common pathways 14998:[DB04833 DB05892] DB04833|Methaqualone CYP3A4 DB05892|RI 624 NGF common genes common pathways 14999:[DB04833 DB07425] DB04833|Methaqualone CYP3A4 DB07425|Sobetirome THRB common genes common pathways 15000:[DB04833 DB02942] DB04833|Methaqualone CYP3A4 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 15001:[DB04833 DB12752] DB04833|Methaqualone CYP3A4 DB12752|Bucindolol CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 15002:[DB04833 DB11723] DB04833|Methaqualone CYP3A4 DB11723|Dutogliptin DPP4 common genes common pathways 15003:[DB04833 DB04153] DB04833|Methaqualone CYP3A4 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0055114| oxidation-reduction process ADH5;CYP3A4 15004:[DB04833 DB05740] DB04833|Methaqualone CYP3A4 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways 15005:[DB04833 DB03756] DB04833|Methaqualone CYP3A4 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PPARA;CYP2C9;PPARG;SREBF1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process SREBF1;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 15006:[DB04833 DB00399] DB04833|Methaqualone CYP3A4 DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 15007:[DB04833 DB06362] DB04833|Methaqualone CYP3A4 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 15008:[DB04833 DB04768] DB04833|Methaqualone CYP3A4 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 15009:[DB04833 DB03052] DB04833|Methaqualone CYP3A4 DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0006629| lipid metabolic process TBXAS1;CYP3A4 GO:0055114| oxidation-reduction process TBXAS1;CYP3A4 15010:[DB04833 DB00437] DB04833|Methaqualone CYP3A4 DB00437|Allopurinol XDH;AOX1;XDH;SLC22A8;SLC22A7 common genes common pathways GO:0017144| drug metabolic process AOX1;CYP3A4 GO:0055114| oxidation-reduction process AOX1;XDH;CYP3A4 15011:[DB04833 DB01024] DB04833|Methaqualone CYP3A4 DB01024|Mycophenolic acid IMPDH1;IMPDH2;UGT1A1;UGT1A9;UGT2B7;UGT1A7;UGT1A6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;UGT2B7 GO:0006805| xenobiotic metabolic process CYP3A4;UGT1A6;UGT1A9 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0055114| oxidation-reduction process IMPDH1;CYP3A4;IMPDH2 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP3A4;UGT1A7;UGT1A6 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;UGT2B7 15012:[DB04833 DB00473] DB04833|Methaqualone CYP3A4 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 15013:[DB04833 DB00441] DB04833|Methaqualone CYP3A4 DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;RRM1 15014:[DB04833 DB02467] DB04833|Methaqualone CYP3A4 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways 15015:[DB04833 DB01046] DB04833|Methaqualone CYP3A4 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways GO:0017144| drug metabolic process CBR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CBR1 15016:[DB04833 DB08103] DB04833|Methaqualone CYP3A4 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways 15017:[DB04833 DB03147] DB04833|Methaqualone CYP3A4 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0006629| lipid metabolic process CYB5R1;ACOX1;ACADM;FDXR;ACADS;ACAD8;CYP3A4;CYB5R3 GO:0006805| xenobiotic metabolic process CYP3A4;CYB5R3;POR;NQO1;NQO2 GO:0055114| oxidation-reduction process TXNRD1;ACAD8;DPYD;ACADS;AIFM1;DLD;XDH;MAOA;CYB5R3;CYP3A4;GCDH;CYB5R1;POR;ERO1B;NDUFA9;GSR;GFER;DAO;IVD;FDXR;IL4I1;NQO2;MAOB;ACADM;NQO1;NOS1;ACOX1 GO:0042738| exogenous drug catabolic process CYP3A4;NOS1 GO:0008202| steroid metabolic process CYB5R1;FDXR;CYB5R3;CYP3A4 15018:[DB04833 DB00235] DB04833|Methaqualone CYP3A4 DB00235|Milrinone PDE3A common genes common pathways GO:0006629| lipid metabolic process PDE3A;CYP3A4 15019:[DB04833 DB03485] DB04833|Methaqualone CYP3A4 DB03485|Alpha-D-Fucose LTF common genes common pathways 15020:[DB04833 DB14562] DB04833|Methaqualone CYP3A4 DB14562|Andexanet alfa TFPI common genes common pathways 15021:[DB04833 DB08824] DB04833|Methaqualone CYP3A4 DB08824|Ioflupane I-123 SLC6A3 common genes common pathways 15022:[DB04833 DB05252] DB04833|Methaqualone CYP3A4 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 15023:[DB04833 DB05015] DB04833|Methaqualone CYP3A4 DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0002933| CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C8 15024:[DB04833 DB07168] DB04833|Methaqualone CYP3A4 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways 15025:[DB04833 DB01927] DB04833|Methaqualone CYP3A4 DB01927|Duroquinone NQO1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP3A4 15026:[DB04833 DB08995] DB04833|Methaqualone CYP3A4 DB08995|Diosmin AHR common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;AHR 15027:[DB04833 DB01390] DB04833|Methaqualone CYP3A4 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways 15028:[DB04833 DB02545] DB04833|Methaqualone CYP3A4 DB02545|Fexaramine NR1H4 common genes common pathways 15029:[DB04833 DB03619] DB04833|Methaqualone CYP3A4 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1 15030:[DB04833 DB06374] DB04833|Methaqualone CYP3A4 DB06374|Elacestrant ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 15031:[DB04833 DB01723] DB04833|Methaqualone CYP3A4 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways 15032:[DB04833 DB01407] DB04833|Methaqualone CYP3A4 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0002933| CYP3A4;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 15033:[DB04833 DB01439] DB04833|Methaqualone CYP3A4 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 15034:[DB04833 DB00072] DB04833|Methaqualone CYP3A4 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0055114| oxidation-reduction process CYP19A1;CYP3A4 15035:[DB04833 DB07497] DB04833|Methaqualone CYP3A4 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PC 15036:[DB04833 DB13146] DB04833|Methaqualone CYP3A4 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;CYP3A4 15037:[DB04833 DB02169] DB04833|Methaqualone CYP3A4 DB02169|9,10-Deepithio-9,10-Didehydroacanthifolicin PPP1CC common genes common pathways 15038:[DB04833 DB05790] DB04833|Methaqualone CYP3A4 DB05790|SR 140333 TACR1 common genes common pathways 15039:[DB04833 DB01429] DB04833|Methaqualone CYP3A4 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 15040:[DB04833 DB09338] DB04833|Methaqualone CYP3A4 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1;PCK1 15041:[DB04833 DB07315] DB04833|Methaqualone CYP3A4 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways 15042:[DB04833 DB09418] DB04833|Methaqualone CYP3A4 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways 15043:[DB04833 DB00526] DB04833|Methaqualone CYP3A4 DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1B1;CYP1A1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A1 GO:0002933| CYP3A4;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;GSTP1;CYP1B1;NQO1 GO:0055114| oxidation-reduction process MPO;CYP2E1;CYP3A4;SOD1;CYP1B1;NQO1;CYP1A1 15044:[DB04833 DB04636] DB04833|Methaqualone CYP3A4 DB04636|Glutamine t-butyl ester QPCT common genes common pathways 15045:[DB04833 DB04676] DB04833|Methaqualone CYP3A4 DB04676|Dansyllysine IGHA2 common genes common pathways 15046:[DB04833 DB05254] DB04833|Methaqualone CYP3A4 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways 15047:[DB04833 DB03276] DB04833|Methaqualone CYP3A4 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways 15048:[DB04833 DB01127] DB04833|Methaqualone CYP3A4 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;NR1I2 15049:[DB04833 DB02552] DB04833|Methaqualone CYP3A4 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 15050:[DB04833 DB08699] DB04833|Methaqualone CYP3A4 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways 15051:[DB04833 DB00380] DB04833|Methaqualone CYP3A4 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways 15052:[DB04833 DB07916] DB04833|Methaqualone CYP3A4 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways 15053:[DB04833 DB03800] DB04833|Methaqualone CYP3A4 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways 15054:[DB04833 DB03956] DB04833|Methaqualone CYP3A4 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways GO:0006629| lipid metabolic process PLCD1;CYP3A4 15055:[DB04833 DB02673] DB04833|Methaqualone CYP3A4 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways 15056:[DB04833 DB07356] DB04833|Methaqualone CYP3A4 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways 15057:[DB04833 DB05052] DB04833|Methaqualone CYP3A4 DB05052|MF101 ESR2 common genes common pathways 15058:[DB04833 DB06243] DB04833|Methaqualone CYP3A4 DB06243|Eflornithine ODC1 common genes common pathways 15059:[DB04833 DB00195] DB04833|Methaqualone CYP3A4 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2D6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP1A2 15060:[DB04833 DB04789] DB04833|Methaqualone CYP3A4 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways 15061:[DB04833 DB06448] DB04833|Methaqualone CYP3A4 DB06448|Lonafarnib FNTA;IGFBP3 common genes common pathways 15062:[DB04833 DB01363] DB04833|Methaqualone CYP3A4 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0055114| oxidation-reduction process MAOB;MAOA;CYP3A4 15063:[DB04833 DB04540] DB04833|Methaqualone CYP3A4 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process RORA;CYP3A4 15064:[DB04833 DB12445] DB04833|Methaqualone CYP3A4 DB12445|Nitroaspirin PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4 15065:[DB04833 DB02381] DB04833|Methaqualone CYP3A4 DB02381|nor-NOHA ARG1 common genes common pathways 15066:[DB04833 DB14540] DB04833|Methaqualone CYP3A4 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP3A4;CYP11B1;CYP11B2;CYP3A7 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A5;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0055114| oxidation-reduction process HSD3B1;HSD11B2;CYP3A5;CYP2C8;CYP3A4;CYP3A7;CYP11B2;CYP11B1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 15067:[DB04833 DB07421] DB04833|Methaqualone CYP3A4 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways 15068:[DB04833 DB08173] DB04833|Methaqualone CYP3A4 DB08173|5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways 15069:[DB04833 DB14503] DB04833|Methaqualone CYP3A4 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways 15070:[DB04833 DB02029] DB04833|Methaqualone CYP3A4 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2 15071:[DB04833 DB11601] DB04833|Methaqualone CYP3A4 DB11601|Tuberculin Purified Protein Derivative TLR2 common genes common pathways 15072:[DB04833 DB03896] DB04833|Methaqualone CYP3A4 DB03896|Triphosphoric acid PAPOLA common genes common pathways 15073:[DB04833 DB06190] DB04833|Methaqualone CYP3A4 DB06190|Solabegron ADRB3 common genes common pathways 15074:[DB04833 DB06787] DB04833|Methaqualone CYP3A4 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 15075:[DB04833 DB03860] DB04833|Methaqualone CYP3A4 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways 15076:[DB04833 DB01228] DB04833|Methaqualone CYP3A4 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 15077:[DB04833 DB02559] DB04833|Methaqualone CYP3A4 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 15078:[DB04833 DB02222] DB04833|Methaqualone CYP3A4 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways 15079:[DB04833 DB07111] DB04833|Methaqualone CYP3A4 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 15080:[DB04833 DB00707] DB04833|Methaqualone CYP3A4 DB00707|Porfimer sodium LDLR;FCGR1A common genes common pathways GO:0006629| lipid metabolic process LDLR;CYP3A4 GO:0008202| steroid metabolic process LDLR;CYP3A4 15081:[DB04833 DB06241] DB04833|Methaqualone CYP3A4 DB06241|Clenoliximab CD4 common genes common pathways 15082:[DB04833 DB02126] DB04833|Methaqualone CYP3A4 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways 15083:[DB04833 DB01252] DB04833|Methaqualone CYP3A4 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;UGT2B7 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0017144| drug metabolic process UGT1A3;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP3A4 15084:[DB04833 DB06262] DB04833|Methaqualone CYP3A4 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process PAH;CYP3A4 15085:[DB04833 DB08214] DB04833|Methaqualone CYP3A4 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 15086:[DB04833 DB02779] DB04833|Methaqualone CYP3A4 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTPN11 15087:[DB04833 DB08495] DB04833|Methaqualone CYP3A4 DB08495|4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways 15088:[DB04833 DB05303] DB04833|Methaqualone CYP3A4 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways 15089:[DB04833 DB07171] DB04833|Methaqualone CYP3A4 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways 15090:[DB04833 DB00002] DB04833|Methaqualone CYP3A4 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 15091:[DB04833 DB09146] DB04833|Methaqualone CYP3A4 DB09146|Iron saccharate HBA1;TF common genes common pathways 15092:[DB04833 DB09449] DB04833|Methaqualone CYP3A4 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways 15093:[DB04833 DB02201] DB04833|Methaqualone CYP3A4 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 15094:[DB04833 DB13269] DB04833|Methaqualone CYP3A4 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways 15095:[DB04833 DB07146] DB04833|Methaqualone CYP3A4 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways 15096:[DB04833 DB07975] DB04833|Methaqualone CYP3A4 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 15097:[DB04833 DB13775] DB04833|Methaqualone CYP3A4 DB13775|Tertatolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 15098:[DB04833 DB08213] DB04833|Methaqualone CYP3A4 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways 15099:[DB04833 DB03693] DB04833|Methaqualone CYP3A4 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways 15100:[DB04833 DB02624] DB04833|Methaqualone CYP3A4 DB02624|Homoserine Lactone SLC9A1 common genes common pathways 15101:[DB04833 DB11348] DB04833|Methaqualone CYP3A4 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways 15102:[DB04833 DB08230] DB04833|Methaqualone CYP3A4 DB08230|5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE PIM1 common genes common pathways 15103:[DB04833 DB12191] DB04833|Methaqualone CYP3A4 DB12191|Obatoclax BCL2 common genes common pathways 15104:[DB04833 DB04352] DB04833|Methaqualone CYP3A4 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 15105:[DB04833 DB03626] DB04833|Methaqualone CYP3A4 DB03626|5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;NQO1 GO:0055114| oxidation-reduction process CYP3A4;NQO1 15106:[DB04833 DB03727] DB04833|Methaqualone CYP3A4 DB03727|Coproporphyrin I UROD common genes common pathways 15107:[DB04833 DB08807] DB04833|Methaqualone CYP3A4 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 15108:[DB04833 DB08406] DB04833|Methaqualone CYP3A4 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 15109:[DB04833 DB06734] DB04833|Methaqualone CYP3A4 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 15110:[DB04833 DB00578] DB04833|Methaqualone CYP3A4 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G4A 15111:[DB04833 DB08461] DB04833|Methaqualone CYP3A4 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways 15112:[DB04833 DB08751] DB04833|Methaqualone CYP3A4 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways 15113:[DB04833 DB07172] DB04833|Methaqualone CYP3A4 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 15114:[DB04833 DB09502] DB04833|Methaqualone CYP3A4 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways 15115:[DB04833 DB01070] DB04833|Methaqualone CYP3A4 DB01070|Dihydrotachysterol VDR common genes common pathways 15116:[DB04833 DB04683] DB04833|Methaqualone CYP3A4 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways 15117:[DB04833 DB05505] DB04833|Methaqualone CYP3A4 DB05505|NM-702 TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TBXAS1 GO:0006629| lipid metabolic process TBXAS1;CYP3A4 15118:[DB04833 DB02763] DB04833|Methaqualone CYP3A4 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways 15119:[DB04833 DB01240] DB04833|Methaqualone CYP3A4 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGIS GO:0006629| lipid metabolic process CYP3A4;PTGIS 15120:[DB04833 DB08847] DB04833|Methaqualone CYP3A4 DB08847|Hydroxyproline SLC36A1 common genes common pathways 15121:[DB04833 DB02383] DB04833|Methaqualone CYP3A4 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways GO:0008202| steroid metabolic process AKR1B10;CYP3A4 GO:0055114| oxidation-reduction process AKR1B1;AKR1A1;AKR1B10;CYP3A4 15122:[DB04833 DB11607] DB04833|Methaqualone CYP3A4 DB11607|Efmoroctocog alfa VWF common genes common pathways 15123:[DB04833 DB00152] DB04833|Methaqualone CYP3A4 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP4B1 GO:0055114| oxidation-reduction process CYP4B1;CYP3A4 15124:[DB04833 DB04964] DB04833|Methaqualone CYP3A4 DB04964|Oregovomab MUC16 common genes common pathways 15125:[DB04833 DB05476] DB04833|Methaqualone CYP3A4 DB05476|WX-UK1 PLAUR common genes common pathways 15126:[DB04833 DB00097] DB04833|Methaqualone CYP3A4 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways 15127:[DB04833 DB00210] DB04833|Methaqualone CYP3A4 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 15128:[DB04833 DB07848] DB04833|Methaqualone CYP3A4 DB07848|5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide F10 common genes common pathways 15129:[DB04833 DB05421] DB04833|Methaqualone CYP3A4 DB05421|CP-122721 TACR1 common genes common pathways 15130:[DB04833 DB01155] DB04833|Methaqualone CYP3A4 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 15131:[DB04833 DB06921] DB04833|Methaqualone CYP3A4 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 15132:[DB04833 DB05431] DB04833|Methaqualone CYP3A4 DB05431|MLN-977 ALOX5 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;CYP3A4 15133:[DB04833 DB02998] DB04833|Methaqualone CYP3A4 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways 15134:[DB04833 DB14635] DB04833|Methaqualone CYP3A4 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2D6;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CBR1;CYP3A4;CYP1A2;CYP2D6;CYP2C9;CYP2B6 GO:0070989| oxidative demethylation CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PPARG;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;GSTP1;CYP2D6;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CBR1;CYP1A2;CYP3A4;CYP2D6;CYP2B6;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C9;CYP3A4;CYP1A2 15135:[DB04833 DB02813] DB04833|Methaqualone CYP3A4 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways 15136:[DB04833 DB04318] DB04833|Methaqualone CYP3A4 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways 15137:[DB04833 DB02142] DB04833|Methaqualone CYP3A4 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways 15138:[DB04833 DB12334] DB04833|Methaqualone CYP3A4 DB12334|Milataxel TUBB1;TUBB common genes common pathways 15139:[DB04833 DB06157] DB04833|Methaqualone CYP3A4 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways 15140:[DB04833 DB08082] DB04833|Methaqualone CYP3A4 DB08082|N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOB 15141:[DB04833 DB07462] DB04833|Methaqualone CYP3A4 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways 15142:[DB04833 DB09303] DB04833|Methaqualone CYP3A4 DB09303|Evolocumab PCSK9 common genes common pathways GO:0006629| lipid metabolic process PCSK9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;PCSK9 15143:[DB04833 DB01284] DB04833|Methaqualone CYP3A4 DB01284|Tetracosactide MC2R common genes common pathways 15144:[DB04833 DB05913] DB04833|Methaqualone CYP3A4 DB05913|OSI-930 KIT;FLT1 common genes common pathways 15145:[DB04833 DB00438] DB04833|Methaqualone CYP3A4 DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 15146:[DB04833 DB06124] DB04833|Methaqualone CYP3A4 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways 15147:[DB04833 DB12200] DB04833|Methaqualone CYP3A4 DB12200|Tivantinib MET common genes common pathways 15148:[DB04833 DB06366] DB04833|Methaqualone CYP3A4 DB06366|Pertuzumab ERBB2 common genes common pathways 15149:[DB04833 DB04590] DB04833|Methaqualone CYP3A4 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways 15150:[DB04833 DB05668] DB04833|Methaqualone CYP3A4 DB05668|Palifosfamide DNMT1 common genes common pathways 15151:[DB04833 DB04758] DB04833|Methaqualone CYP3A4 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways 15152:[DB04833 DB05404] DB04833|Methaqualone CYP3A4 DB05404|AZD 3355 TP53 common genes common pathways 15153:[DB04833 DB06101] DB04833|Methaqualone CYP3A4 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways 15154:[DB04833 DB04461] DB04833|Methaqualone CYP3A4 DB04461|Coproporphyrinogen III UROD common genes common pathways 15155:[DB04833 DB07039] DB04833|Methaqualone CYP3A4 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways 15156:[DB04833 DB11059] DB04833|Methaqualone CYP3A4 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways 15157:[DB04833 DB03403] DB04833|Methaqualone CYP3A4 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 15158:[DB04833 DB00685] DB04833|Methaqualone CYP3A4 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 15159:[DB04833 DB08497] DB04833|Methaqualone CYP3A4 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways 15160:[DB04833 DB08155] DB04833|Methaqualone CYP3A4 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways 15161:[DB04833 DB07428] DB04833|Methaqualone CYP3A4 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 15162:[DB04833 DB04074] DB04833|Methaqualone CYP3A4 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 15163:[DB04833 DB03239] DB04833|Methaqualone CYP3A4 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways 15164:[DB04833 DB01102] DB04833|Methaqualone CYP3A4 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways 15165:[DB04833 DB04843] DB04833|Methaqualone CYP3A4 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways 15166:[DB04833 DB07067] DB04833|Methaqualone CYP3A4 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways 15167:[DB04833 DB05191] DB04833|Methaqualone CYP3A4 DB05191|Atl146e ADORA2A common genes common pathways 15168:[DB04833 DB01834] DB04833|Methaqualone CYP3A4 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP3A4 15169:[DB04833 DB00859] DB04833|Methaqualone CYP3A4 DB00859|Penicillamine SLCO1B1 common genes common pathways 15170:[DB04833 DB12458] DB04833|Methaqualone CYP3A4 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways 15171:[DB04833 DB00655] DB04833|Methaqualone CYP3A4 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2B6;CYP3A5;CYP1B1;CYP3A4;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1;CYP2C9;CYP2B6 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP1A2;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C9;CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0055114| oxidation-reduction process CYP4A11;CYP1A2;CYP2E1;CYP3A4;CYP1B1;CYP3A5;CYP2B6;CYP1A1;CYP2C9;CYP19A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2B6 15172:[DB04833 DB00902] DB04833|Methaqualone CYP3A4 DB00902|Methdilazine HRH1 common genes common pathways 15173:[DB04833 DB05087] DB04833|Methaqualone CYP3A4 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways 15174:[DB04833 DB04840] DB04833|Methaqualone CYP3A4 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A1 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A1;CYP2D6 GO:0002933| CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 15175:[DB04833 DB00886] DB04833|Methaqualone CYP3A4 DB00886|Omapatrilat ACE;MME common genes common pathways 15176:[DB04833 DB14642] DB04833|Methaqualone CYP3A4 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways 15177:[DB04833 DB04865] DB04833|Methaqualone CYP3A4 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 15178:[DB04833 DB06536] DB04833|Methaqualone CYP3A4 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA 15179:[DB04833 DB08760] DB04833|Methaqualone CYP3A4 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 15180:[DB04833 DB12945] DB04833|Methaqualone CYP3A4 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 15181:[DB04833 DB04889] DB04833|Methaqualone CYP3A4 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process MAOB;CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 15182:[DB04833 DB00782] DB04833|Methaqualone CYP3A4 DB00782|Propantheline CHRM1 common genes common pathways 15183:[DB04833 DB14508] DB04833|Methaqualone CYP3A4 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways 15184:[DB04833 DB04187] DB04833|Methaqualone CYP3A4 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways 15185:[DB04833 DB01569] DB04833|Methaqualone CYP3A4 DB01569|Formebolone HSD11B2 common genes common pathways GO:0055114| oxidation-reduction process HSD11B2;CYP3A4 15186:[DB04833 DB05434] DB04833|Methaqualone CYP3A4 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways 15187:[DB04833 DB06211] DB04833|Methaqualone CYP3A4 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0006805| xenobiotic metabolic process DPEP1;CYP3A4 15188:[DB04833 DB00517] DB04833|Methaqualone CYP3A4 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways 15189:[DB04833 DB00131] DB04833|Methaqualone CYP3A4 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0006629| lipid metabolic process ACSL1;PRKAA1;PRKAB1;PRKAB2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;PRKAA1 15190:[DB04833 DB00594] DB04833|Methaqualone CYP3A4 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0055114| oxidation-reduction process AOC1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;AOC1 15191:[DB04833 DB00569] DB04833|Methaqualone CYP3A4 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways 15192:[DB04833 DB11358] DB04833|Methaqualone CYP3A4 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;FADS1;FADS2 GO:0006629| lipid metabolic process CYP3A4;ELOVL5;FADS1;FADS2 15193:[DB04833 DB09205] DB04833|Methaqualone CYP3A4 DB09205|Moxisylyte ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;BCHE common genes common pathways 15194:[DB04833 DB04066] DB04833|Methaqualone CYP3A4 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways GO:0055114| oxidation-reduction process PTGR1;CYP3A4 15195:[DB04833 DB09282] DB04833|Methaqualone CYP3A4 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 15196:[DB04833 DB00630] DB04833|Methaqualone CYP3A4 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 15197:[DB04833 DB08326] DB04833|Methaqualone CYP3A4 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ACSBG1 15198:[DB04833 DB08846] DB04833|Methaqualone CYP3A4 DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0002933| CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;SQLE;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 15199:[DB04833 DB03349] DB04833|Methaqualone CYP3A4 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways 15200:[DB04833 DB02872] DB04833|Methaqualone CYP3A4 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways 15201:[DB04833 DB08822] DB04833|Methaqualone CYP3A4 DB08822|Azilsartan medoxomil AGTR1 common genes common pathways 15202:[DB04833 DB05418] DB04833|Methaqualone CYP3A4 DB05418|GW 597599 TACR1 common genes common pathways 15203:[DB04833 DB05218] DB04833|Methaqualone CYP3A4 DB05218|PN0621 TNF common genes common pathways 15204:[DB04833 DB07976] DB04833|Methaqualone CYP3A4 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 15205:[DB04833 DB02499] DB04833|Methaqualone CYP3A4 DB02499|Dinor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways 15206:[DB04833 DB00276] DB04833|Methaqualone CYP3A4 DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways 15207:[DB04833 DB02109] DB04833|Methaqualone CYP3A4 DB02109|Hadacidin purA;ADSSL1 common genes common pathways 15208:[DB04833 DB03415] DB04833|Methaqualone CYP3A4 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ACADM GO:0006629| lipid metabolic process CYP3A4;ACADM 15209:[DB04833 DB06999] DB04833|Methaqualone CYP3A4 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways 15210:[DB04833 DB14018] DB04833|Methaqualone CYP3A4 DB14018|Bromotheophylline CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 15211:[DB04833 DB04883] DB04833|Methaqualone CYP3A4 DB04883|Darusentan EDNRA common genes common pathways 15212:[DB04833 DB00878] DB04833|Methaqualone CYP3A4 DB00878|Chlorhexidine HNMT;cat common genes common pathways 15213:[DB04833 DB09265] DB04833|Methaqualone CYP3A4 DB09265|Lixisenatide GLP1R common genes common pathways 15214:[DB04833 DB07621] DB04833|Methaqualone CYP3A4 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2A6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP2A6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2A6 15215:[DB04833 DB11429] DB04833|Methaqualone CYP3A4 DB11429|Mibolerone AR common genes common pathways 15216:[DB04833 DB05466] DB04833|Methaqualone CYP3A4 DB05466|R673 TACR1 common genes common pathways 15217:[DB04833 DB05752] DB04833|Methaqualone CYP3A4 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 15218:[DB04833 DB07804] DB04833|Methaqualone CYP3A4 DB07804|5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE F10 common genes common pathways 15219:[DB04833 DB04805] DB04833|Methaqualone CYP3A4 DB04805|Virginiamycin S1 RPL37 common genes common pathways 15220:[DB04833 DB06460] DB04833|Methaqualone CYP3A4 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways 15221:[DB04833 DB01019] DB04833|Methaqualone CYP3A4 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways 15222:[DB04833 DB13800] DB04833|Methaqualone CYP3A4 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways 15223:[DB04833 DB04527] DB04833|Methaqualone CYP3A4 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways 15224:[DB04833 DB08613] DB04833|Methaqualone CYP3A4 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways 15225:[DB04833 DB01496] DB04833|Methaqualone CYP3A4 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 15226:[DB04833 DB05194] DB04833|Methaqualone CYP3A4 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways 15227:[DB04833 DB07384] DB04833|Methaqualone CYP3A4 DB07384|1-ACETYL-2-CARBOXYPIPERIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ATP5B 15228:[DB04833 DB13994] DB04833|Methaqualone CYP3A4 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 15229:[DB04833 DB00414] DB04833|Methaqualone CYP3A4 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CBR1;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CBR1;CYP3A4 15230:[DB04833 DB02670] DB04833|Methaqualone CYP3A4 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways 15231:[DB04833 DB06925] DB04833|Methaqualone CYP3A4 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways 15232:[DB04833 DB08502] DB04833|Methaqualone CYP3A4 DB08502|Capravirine CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 15233:[DB04833 DB05685] DB04833|Methaqualone CYP3A4 DB05685|FX06 CDH5 common genes common pathways 15234:[DB04833 DB01548] DB04833|Methaqualone CYP3A4 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways 15235:[DB04833 DB11256] DB04833|Methaqualone CYP3A4 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways 15236:[DB04833 DB11064] DB04833|Methaqualone CYP3A4 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 15237:[DB04833 DB05044] DB04833|Methaqualone CYP3A4 DB05044|PSN357 PYGL common genes common pathways 15238:[DB04833 DB03926] DB04833|Methaqualone CYP3A4 DB03926|5-Alpha-Androstane-3-Beta,17-Alpha-Diol SHBG common genes common pathways 15239:[DB04833 DB07720] DB04833|Methaqualone CYP3A4 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways 15240:[DB04833 DB07694] DB04833|Methaqualone CYP3A4 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways 15241:[DB04833 DB05201] DB04833|Methaqualone CYP3A4 DB05201|V24343 CNR1 common genes common pathways 15242:[DB04833 DB05451] DB04833|Methaqualone CYP3A4 DB05451|P54 NFKB2;NFKB1 common genes common pathways 15243:[DB04833 DB03566] DB04833|Methaqualone CYP3A4 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process TXNRD1;CYP3A4 15244:[DB04833 DB09331] DB04833|Methaqualone CYP3A4 DB09331|Daratumumab CD38 common genes common pathways 15245:[DB04833 DB06111] DB04833|Methaqualone CYP3A4 DB06111|AB192 MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;CYP3A4 15246:[DB04833 DB00008] DB04833|Methaqualone CYP3A4 DB00008|Peginterferon alfa-2a IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 15247:[DB04833 DB04915] DB04833|Methaqualone CYP3A4 DB04915|Idronoxil ENOX2 common genes common pathways GO:0055114| oxidation-reduction process ENOX2;CYP3A4 15248:[DB04833 DB05091] DB04833|Methaqualone CYP3A4 DB05091|M0002 AVPR2 common genes common pathways 15249:[DB04833 DB00704] DB04833|Methaqualone CYP3A4 DB00704|Naltrexone OPRD1;OPRM1;OPRK1;SIGMAR1;UGT1A1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 15250:[DB04833 DB08172] DB04833|Methaqualone CYP3A4 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 15251:[DB04833 DB00790] DB04833|Methaqualone CYP3A4 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways 15252:[DB04833 DB01962] DB04833|Methaqualone CYP3A4 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways 15253:[DB04833 DB01835] DB04833|Methaqualone CYP3A4 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 15254:[DB04833 DB03419] DB04833|Methaqualone CYP3A4 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DPYD 15255:[DB04833 DB01296] DB04833|Methaqualone CYP3A4 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP3A4 15256:[DB04833 DB12866] DB04833|Methaqualone CYP3A4 DB12866|Pradigastat SLC22A8 common genes common pathways 15257:[DB04833 DB02974] DB04833|Methaqualone CYP3A4 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4 GO:0055114| oxidation-reduction process CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2B6;CYP3A4 15258:[DB04833 DB01412] DB04833|Methaqualone CYP3A4 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2 15259:[DB04833 DB04674] DB04833|Methaqualone CYP3A4 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;AKR1C1 GO:0055114| oxidation-reduction process AKR1C1;CYP3A4 15260:[DB04833 DB13150] DB04833|Methaqualone CYP3A4 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways 15261:[DB04833 DB00521] DB04833|Methaqualone CYP3A4 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 15262:[DB04833 DB06842] DB04833|Methaqualone CYP3A4 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways 15263:[DB04833 DB05419] DB04833|Methaqualone CYP3A4 DB05419|ADX-10061 CALY common genes common pathways 15264:[DB04833 DB07695] DB04833|Methaqualone CYP3A4 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways 15265:[DB04833 DB07851] DB04833|Methaqualone CYP3A4 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways 15266:[DB04833 DB09296] DB04833|Methaqualone CYP3A4 DB09296|Ombitasvir CYP2C8;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8 15267:[DB04833 DB06782] DB04833|Methaqualone CYP3A4 DB06782|Dimercaprol APP common genes common pathways 15268:[DB04833 DB00852] DB04833|Methaqualone CYP3A4 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process MAOA;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 15269:[DB04833 DB03083] DB04833|Methaqualone CYP3A4 DB03083|IC261 CSNK1G2 common genes common pathways 15270:[DB04833 DB02773] DB04833|Methaqualone CYP3A4 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4 15271:[DB04833 DB06769] DB04833|Methaqualone CYP3A4 DB06769|Bendamustine CYP1A2 common genes common pathways GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 15272:[DB04833 DB05022] DB04833|Methaqualone CYP3A4 DB05022|Amonafide TOP2A;TOP2B common genes common pathways 15273:[DB04833 DB00192] DB04833|Methaqualone CYP3A4 DB00192|Indecainide SCN5A common genes common pathways 15274:[DB04833 DB00534] DB04833|Methaqualone CYP3A4 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0055114| oxidation-reduction process ALDH5A1;CYP3A4 15275:[DB04833 DB08299] DB04833|Methaqualone CYP3A4 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways 15276:[DB04833 DB00229] DB04833|Methaqualone CYP3A4 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways 15277:[DB04833 DB05210] DB04833|Methaqualone CYP3A4 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways 15278:[DB04833 DB00963] DB04833|Methaqualone CYP3A4 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4 15279:[DB04833 DB07872] DB04833|Methaqualone CYP3A4 DB07872|5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide F10 common genes common pathways 15280:[DB04833 DB01819] DB04833|Methaqualone CYP3A4 DB01819|Phosphoenolpyruvate aroG;kdsA;ENO3;PCK1;kdsA;SLCO2A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PCK1 15281:[DB04833 DB05305] DB04833|Methaqualone CYP3A4 DB05305|Cintredekin Besudotox IL13 common genes common pathways 15282:[DB04833 DB06138] DB04833|Methaqualone CYP3A4 DB06138|IRL-1620 EDNRB common genes common pathways 15283:[DB04833 DB07963] DB04833|Methaqualone CYP3A4 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways 15284:[DB04833 DB11491] DB04833|Methaqualone CYP3A4 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 15285:[DB04833 DB02635] DB04833|Methaqualone CYP3A4 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways 15286:[DB04833 DB06751] DB04833|Methaqualone CYP3A4 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways 15287:[DB04833 DB04926] DB04833|Methaqualone CYP3A4 DB04926|Neramexane GRIN3A common genes common pathways 15288:[DB04833 DB07132] DB04833|Methaqualone CYP3A4 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways 15289:[DB04833 DB01650] DB04833|Methaqualone CYP3A4 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways 15290:[DB04833 DB03928] DB04833|Methaqualone CYP3A4 DB03928|Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol CTH common genes common pathways 15291:[DB04833 DB01257] DB04833|Methaqualone CYP3A4 DB01257|Eculizumab C5 common genes common pathways 15292:[DB04833 DB04392] DB04833|Methaqualone CYP3A4 DB04392|Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] NQO1;azoR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NQO1 GO:0006805| xenobiotic metabolic process CYP3A4;NQO1 15293:[DB04833 DB03611] DB04833|Methaqualone CYP3A4 DB03611|L-2-amino-4-methoxy-cis-but-3-enoic acid MAT1A common genes common pathways 15294:[DB04833 DB02825] DB04833|Methaqualone CYP3A4 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways 15295:[DB04833 DB02854] DB04833|Methaqualone CYP3A4 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0008202| steroid metabolic process SULT2A1;CYP3A4 GO:0006629| lipid metabolic process HSD17B11;SULT2A1;CYP3A4 GO:0055114| oxidation-reduction process HSD17B11;CYP3A4 15296:[DB04833 DB06534] DB04833|Methaqualone CYP3A4 DB06534|Thrombopoietin MPL common genes common pathways 15297:[DB04833 DB05166] DB04833|Methaqualone CYP3A4 DB05166|APD668 GPR119 common genes common pathways 15298:[DB04833 DB12035] DB04833|Methaqualone CYP3A4 DB12035|Sarecycline ABCB1 common genes common pathways 15299:[DB04833 DB11577] DB04833|Methaqualone CYP3A4 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0006805| xenobiotic metabolic process AHR;CYP3A4 15300:[DB04833 DB01288] DB04833|Methaqualone CYP3A4 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways 15301:[DB04833 DB12077] DB04833|Methaqualone CYP3A4 DB12077|Urelumab TNFRSF9 common genes common pathways 15302:[DB04833 DB06274] DB04833|Methaqualone CYP3A4 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways 15303:[DB04833 DB11431] DB04833|Methaqualone CYP3A4 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;CYP3A43;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP3A5 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0002933| CYP3A5;CYP3A7;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP3A5 GO:0070989| oxidative demethylation CYP3A4;CYP3A5 GO:0017144| drug metabolic process CYP3A4 15304:[DB04833 DB06292] DB04833|Methaqualone CYP3A4 DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP1A2;CYP2C9 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CYP2D6;CYP3A4;CYP2A6;CYP1A2 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C9;UGT2B4;UGT1A9;CYP2D6 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;UGT2B7;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0002933| CYP1A1;CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP2D6;UGT1A9;CYP1A1;CYP2C9;CYP1A2;CYP2A6;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2A6;CYP3A4;CYP1A2;UGT2B7 15305:[DB04833 DB05042] DB04833|Methaqualone CYP3A4 DB05042|SGS518 HTR6 common genes common pathways 15306:[DB04833 DB05688] DB04833|Methaqualone CYP3A4 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways 15307:[DB04833 DB04958] DB04833|Methaqualone CYP3A4 DB04958|Epratuzumab CD22 common genes common pathways 15308:[DB04833 DB04166] DB04833|Methaqualone CYP3A4 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways GO:0055114| oxidation-reduction process IL4I1;DAO;CYP3A4 15309:[DB04833 DB00047] DB04833|Methaqualone CYP3A4 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways 15310:[DB04833 DB12890] DB04833|Methaqualone CYP3A4 DB12890|Dihydrexidine DRD1 common genes common pathways 15311:[DB04833 DB00130] DB04833|Methaqualone CYP3A4 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0017144| drug metabolic process CAD;CYP3A4 15312:[DB04833 DB00459] DB04833|Methaqualone CYP3A4 DB00459|Acitretin RXRA;RARA;RARB;RARG;RXRB;RXRG;RBP1;CYP26A1;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP26A1 GO:0006805| xenobiotic metabolic process CYP26A1;CYP3A4 15313:[DB04833 DB14069] DB04833|Methaqualone CYP3A4 DB14069|ONT-093 ABCB1 common genes common pathways 15314:[DB04833 DB07427] DB04833|Methaqualone CYP3A4 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 15315:[DB04833 DB00117] DB04833|Methaqualone CYP3A4 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways 15316:[DB04833 DB04472] DB04833|Methaqualone CYP3A4 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways 15317:[DB04833 DB06749] DB04833|Methaqualone CYP3A4 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways 15318:[DB04833 DB00978] DB04833|Methaqualone CYP3A4 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 15319:[DB04833 DB06714] DB04833|Methaqualone CYP3A4 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways 15320:[DB04833 DB05034] DB04833|Methaqualone CYP3A4 DB05034|Ularitide NPR1 common genes common pathways 15321:[DB04833 DB08210] DB04833|Methaqualone CYP3A4 DB08210|2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE GCK common genes common pathways 15322:[DB04833 DB04602] DB04833|Methaqualone CYP3A4 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 15323:[DB04833 DB01561] DB04833|Methaqualone CYP3A4 DB01561|Androstanedione HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process HSD17B1;CYP3A4 GO:0006629| lipid metabolic process HSD17B1;CYP3A4 15324:[DB04833 DB07605] DB04833|Methaqualone CYP3A4 DB07605|2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE F10 common genes common pathways 15325:[DB04833 DB03917] DB04833|Methaqualone CYP3A4 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways 15326:[DB04833 DB05290] DB04833|Methaqualone CYP3A4 DB05290|SPP 301 EDNRA common genes common pathways 15327:[DB04833 DB09142] DB04833|Methaqualone CYP3A4 DB09142|Sincalide SLCO1B3 common genes common pathways 15328:[DB04833 DB04299] DB04833|Methaqualone CYP3A4 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways 15329:[DB04833 DB00529] DB04833|Methaqualone CYP3A4 DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 15330:[DB04833 DB03807] DB04833|Methaqualone CYP3A4 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways 15331:[DB04833 DB07194] DB04833|Methaqualone CYP3A4 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways 15332:[DB04833 DB09108] DB04833|Methaqualone CYP3A4 DB09108|Simoctocog Alfa VWF common genes common pathways 15333:[DB04833 DB07423] DB04833|Methaqualone CYP3A4 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways 15334:[DB04833 DB02323] DB04833|Methaqualone CYP3A4 DB02323|EM-1745 HSD17B1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HSD17B1 GO:0055114| oxidation-reduction process CYP3A4;HSD17B1 15335:[DB04833 DB00713] DB04833|Methaqualone CYP3A4 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways 15336:[DB04833 DB00305] DB04833|Methaqualone CYP3A4 DB00305|Mitomycin POR common genes common pathways GO:0055114| oxidation-reduction process POR;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;POR 15337:[DB04833 DB02542] DB04833|Methaqualone CYP3A4 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways 15338:[DB04833 DB01047] DB04833|Methaqualone CYP3A4 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 15339:[DB04833 DB04464] DB04833|Methaqualone CYP3A4 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0055114| oxidation-reduction process MT-CO2;MT-CO1;MT-ND1;CYP3A4 15340:[DB04833 DB02796] DB04833|Methaqualone CYP3A4 DB02796|9-Deazainosine PNP common genes common pathways 15341:[DB04833 DB02162] DB04833|Methaqualone CYP3A4 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways 15342:[DB04833 DB08374] DB04833|Methaqualone CYP3A4 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways 15343:[DB04833 DB04260] DB04833|Methaqualone CYP3A4 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways 15344:[DB04833 DB08357] DB04833|Methaqualone CYP3A4 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways 15345:[DB04833 DB00010] DB04833|Methaqualone CYP3A4 DB00010|Sermorelin GHRHR common genes common pathways 15346:[DB04833 DB08362] DB04833|Methaqualone CYP3A4 DB08362|N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE CSNK2A1 common genes common pathways 15347:[DB04833 DB08900] DB04833|Methaqualone CYP3A4 DB08900|Teduglutide GLP2R common genes common pathways 15348:[DB04833 DB03523] DB04833|Methaqualone CYP3A4 DB03523|Brequinar DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 15349:[DB04833 DB13167] DB04833|Methaqualone CYP3A4 DB13167|Alclofenac PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 15350:[DB04833 DB05941] DB04833|Methaqualone CYP3A4 DB05941|Leronlimab CCR5 common genes common pathways 15351:[DB04833 DB00182] DB04833|Methaqualone CYP3A4 DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process MAOA;CYP2A6;CYP3A4;MAOB;CYP2D6 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 15352:[DB04833 DB03589] DB04833|Methaqualone CYP3A4 DB03589|Alpha-Ketomalonic Acid ME2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ME2 15353:[DB04833 DB00036] DB04833|Methaqualone CYP3A4 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways 15354:[DB04833 DB07567] DB04833|Methaqualone CYP3A4 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 15355:[DB04833 DB03660] DB04833|Methaqualone CYP3A4 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways 15356:[DB04833 DB06916] DB04833|Methaqualone CYP3A4 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 15357:[DB04833 DB12271] DB04833|Methaqualone CYP3A4 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways 15358:[DB04833 DB03060] DB04833|Methaqualone CYP3A4 DB03060|Sri-9662 DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 15359:[DB04833 DB01307] DB04833|Methaqualone CYP3A4 DB01307|Insulin Detemir INSR;ALB common genes common pathways 15360:[DB04833 DB01571] DB04833|Methaqualone CYP3A4 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 15361:[DB04833 DB01408] DB04833|Methaqualone CYP3A4 DB01408|Bambuterol ADRB2;BCHE common genes common pathways 15362:[DB04833 DB02689] DB04833|Methaqualone CYP3A4 DB02689|S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine ARG1 common genes common pathways 15363:[DB04833 DB00340] DB04833|Methaqualone CYP3A4 DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways 15364:[DB04833 DB08737] DB04833|Methaqualone CYP3A4 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 15365:[DB04833 DB04343] DB04833|Methaqualone CYP3A4 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways 15366:[DB04833 DB04478] DB04833|Methaqualone CYP3A4 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SORD 15367:[DB04833 DB00324] DB04833|Methaqualone CYP3A4 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 15368:[DB04833 DB07380] DB04833|Methaqualone CYP3A4 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 15369:[DB04833 DB02067] DB04833|Methaqualone CYP3A4 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways 15370:[DB04833 DB03341] DB04833|Methaqualone CYP3A4 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways 15371:[DB04833 DB02477] DB04833|Methaqualone CYP3A4 DB02477|[Cyclohexylethyl]-[[[[4-[2-Methyl-1-Imidazolyl-Butyl]Phenyl]Acetyl]-Seryl]-Lysinyl]-Amine NMT1 common genes common pathways 15372:[DB04833 DB05072] DB04833|Methaqualone CYP3A4 DB05072|AV608 TACR1 common genes common pathways 15373:[DB04833 DB13878] DB04833|Methaqualone CYP3A4 DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;CYP3A7 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP3A5 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A5;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0070989| oxidative demethylation CYP3A5;CYP3A4 15374:[DB04833 DB02648] DB04833|Methaqualone CYP3A4 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways GO:0006629| lipid metabolic process CROT;CRAT;CYP3A4 15375:[DB04833 DB06406] DB04833|Methaqualone CYP3A4 DB06406|Idraparinux F10 common genes common pathways 15376:[DB04833 DB02583] DB04833|Methaqualone CYP3A4 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 15377:[DB04833 DB04230] DB04833|Methaqualone CYP3A4 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 15378:[DB04833 DB02078] DB04833|Methaqualone CYP3A4 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways 15379:[DB04833 DB00261] DB04833|Methaqualone CYP3A4 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PDE3A GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 15380:[DB04833 DB01942] DB04833|Methaqualone CYP3A4 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process NOS1;GPHN;HMOX1;CYP3A4;CTBP1 GO:0042738| exogenous drug catabolic process CYP3A4;NOS1 15381:[DB04833 DB08447] DB04833|Methaqualone CYP3A4 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 15382:[DB04833 DB08258] DB04833|Methaqualone CYP3A4 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2 15383:[DB04833 DB13508] DB04833|Methaqualone CYP3A4 DB13508|Cloranolol CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 15384:[DB04833 DB01007] DB04833|Methaqualone CYP3A4 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0055114| oxidation-reduction process CYP19A1;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CYP51A1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP51A1 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP51A1;CYP2C19;CYP2C8 15385:[DB04833 DB06711] DB04833|Methaqualone CYP3A4 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways 15386:[DB04833 DB00513] DB04833|Methaqualone CYP3A4 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;LPA GO:0055114| oxidation-reduction process CYP3A4;AOX1 GO:0017144| drug metabolic process CYP3A4;AOX1 15387:[DB04833 DB09481] DB04833|Methaqualone CYP3A4 DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways 15388:[DB04833 DB07666] DB04833|Methaqualone CYP3A4 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways 15389:[DB04833 DB04237] DB04833|Methaqualone CYP3A4 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways 15390:[DB04833 DB03115] DB04833|Methaqualone CYP3A4 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways 15391:[DB04833 DB03924] DB04833|Methaqualone CYP3A4 DB03924|5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone CSNK2A1 common genes common pathways 15392:[DB04833 DB02489] DB04833|Methaqualone CYP3A4 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 15393:[DB04833 DB13746] DB04833|Methaqualone CYP3A4 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8;CYP2C19;CYP2C9 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2C19 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP2C19;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2C19;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0036378| CYP3A4 15394:[DB04833 DB03802] DB04833|Methaqualone CYP3A4 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 15395:[DB04833 DB04365] DB04833|Methaqualone CYP3A4 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways 15396:[DB04833 DB01593] DB04833|Methaqualone CYP3A4 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0006629| lipid metabolic process APOE;CLU;APOBR;APOA1;PON1;C3;CYP3A4;APOL1 GO:0055114| oxidation-reduction process GAPDHS;PDIA3;PRDX1;CYP3A4;SOD1;P4HB;ADH1C;CP;CCS GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0008202| steroid metabolic process APOBR;APOA1;APOE;APOL1;CYP3A4 15397:[DB04833 DB00075] DB04833|Methaqualone CYP3A4 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 15398:[DB04833 DB13893] DB04833|Methaqualone CYP3A4 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G10 15399:[DB04833 DB08387] DB04833|Methaqualone CYP3A4 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 15400:[DB04833 DB05932] DB04833|Methaqualone CYP3A4 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways 15401:[DB04833 DB06786] DB04833|Methaqualone CYP3A4 DB06786|Halcinonide SMO;CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 15402:[DB04833 DB01101] DB04833|Methaqualone CYP3A4 DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;DPYD;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CES1;CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 15403:[DB04833 DB07513] DB04833|Methaqualone CYP3A4 DB07513|7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOB 15404:[DB04833 DB13141] DB04833|Methaqualone CYP3A4 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A7;CYP3A4;CYP3A43 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0002933| CYP3A5;CYP3A7;CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP3A5 GO:0070989| oxidative demethylation CYP3A4;CYP3A5 GO:0017144| drug metabolic process CYP3A4 15405:[DB04833 DB05096] DB04833|Methaqualone CYP3A4 DB05096|LY2140023 GRM2;GRM3 common genes common pathways 15406:[DB04833 DB05343] DB04833|Methaqualone CYP3A4 DB05343|Arundic acid S100B common genes common pathways 15407:[DB04833 DB00134] DB04833|Methaqualone CYP3A4 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process MSRB1;MSRB2;MSRA;MTRR;CYP3A4;MTHFR 15408:[DB04833 DB04973] DB04833|Methaqualone CYP3A4 DB04973|LErafAON RAF1 common genes common pathways 15409:[DB04833 DB05895] DB04833|Methaqualone CYP3A4 DB05895|HGS-TR2J TNFRSF10B common genes common pathways 15410:[DB04833 DB02943] DB04833|Methaqualone CYP3A4 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways 15411:[DB04833 DB01327] DB04833|Methaqualone CYP3A4 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006629| lipid metabolic process PON1;CYP3A4 GO:0055114| oxidation-reduction process ABCC4;CYP3A4 15412:[DB04833 DB07280] DB04833|Methaqualone CYP3A4 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 15413:[DB04833 DB03182] DB04833|Methaqualone CYP3A4 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 15414:[DB04833 DB02021] DB04833|Methaqualone CYP3A4 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;AKR1B1;AKR1B10 GO:0008202| steroid metabolic process AKR1B10;CYP3A4 15415:[DB04833 DB04616] DB04833|Methaqualone CYP3A4 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways 15416:[DB04833 DB13923] DB04833|Methaqualone CYP3A4 DB13923|Emicizumab F9;F10 common genes common pathways 15417:[DB04833 DB14061] DB04833|Methaqualone CYP3A4 DB14061|Hycanthone ABCB1 common genes common pathways 15418:[DB04833 DB00112] DB04833|Methaqualone CYP3A4 DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 15419:[DB04833 DB05771] DB04833|Methaqualone CYP3A4 DB05771|LLL-3348 IL10 common genes common pathways 15420:[DB04833 DB07840] DB04833|Methaqualone CYP3A4 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways 15421:[DB04833 DB05235] DB04833|Methaqualone CYP3A4 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0055114| oxidation-reduction process CRYM;CYP3A4 15422:[DB04833 DB01295] DB04833|Methaqualone CYP3A4 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 15423:[DB04833 DB08164] DB04833|Methaqualone CYP3A4 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways 15424:[DB04833 DB06655] DB04833|Methaqualone CYP3A4 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways 15425:[DB04833 DB05268] DB04833|Methaqualone CYP3A4 DB05268|iCo-007 RAF1 common genes common pathways 15426:[DB04833 DB04539] DB04833|Methaqualone CYP3A4 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 15427:[DB04833 DB00162] DB04833|Methaqualone CYP3A4 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;ALDH1A3;RDH12;DHRS4;ALDH1A2;RDH5;RDH8;CYP3A4;RDH14;CYP26A1;RDH11;RDH13;RETSAT;ALDH1A1;DHRS3 GO:0006805| xenobiotic metabolic process CYP26A1;CYP3A4 GO:0006629| lipid metabolic process APOD;RBP3;CYP3A4;HPGDS GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0002933| CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process DHRS4;CYP1A1;CYP3A4 15428:[DB04833 DB07908] DB04833|Methaqualone CYP3A4 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways 15429:[DB04833 DB06586] DB04833|Methaqualone CYP3A4 DB06586|Cetilistat PNLIP common genes common pathways GO:0006629| lipid metabolic process PNLIP;CYP3A4 15430:[DB04833 DB00174] DB04833|Methaqualone CYP3A4 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways 15431:[DB04833 DB04873] DB04833|Methaqualone CYP3A4 DB04873|Piboserod HTR4 common genes common pathways 15432:[DB04833 DB07046] DB04833|Methaqualone CYP3A4 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways 15433:[DB04833 DB01031] DB04833|Methaqualone CYP3A4 DB01031|Ethinamate CA1;CA2 common genes common pathways 15434:[DB04833 DB06779] DB04833|Methaqualone CYP3A4 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways 15435:[DB04833 DB11937] DB04833|Methaqualone CYP3A4 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways GO:0006805| xenobiotic metabolic process AHR;CYP3A4 15436:[DB04833 DB06159] DB04833|Methaqualone CYP3A4 DB06159|Rubitecan TOP1 common genes common pathways 15437:[DB04833 DB05501] DB04833|Methaqualone CYP3A4 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways 15438:[DB04833 DB07771] DB04833|Methaqualone CYP3A4 DB07771|[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID KRAS;FNTA;FNTB common genes common pathways 15439:[DB04833 DB03839] DB04833|Methaqualone CYP3A4 DB03839|D-Tyrosine SLC16A10 common genes common pathways 15440:[DB04833 DB02400] DB04833|Methaqualone CYP3A4 DB02400|5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NQO1 GO:0006805| xenobiotic metabolic process CYP3A4;NQO1 15441:[DB04833 DB06862] DB04833|Methaqualone CYP3A4 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways 15442:[DB04833 DB06492] DB04833|Methaqualone CYP3A4 DB06492|Mirococept C3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;C3 15443:[DB04833 DB01426] DB04833|Methaqualone CYP3A4 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways 15444:[DB04833 DB04551] DB04833|Methaqualone CYP3A4 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways 15445:[DB04833 DB12520] DB04833|Methaqualone CYP3A4 DB12520|Plozalizumab CCR2 common genes common pathways 15446:[DB04833 DB07558] DB04833|Methaqualone CYP3A4 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways 15447:[DB04833 DB08830] DB04833|Methaqualone CYP3A4 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways 15448:[DB04833 DB07958] DB04833|Methaqualone CYP3A4 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 15449:[DB04833 DB00462] DB04833|Methaqualone CYP3A4 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways 15450:[DB04833 DB04850] DB04833|Methaqualone CYP3A4 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 15451:[DB04833 DB05142] DB04833|Methaqualone CYP3A4 DB05142|ND7001 PDE2A;PDE2A common genes common pathways 15452:[DB04833 DB06266] DB04833|Methaqualone CYP3A4 DB06266|Lonidamine CFTR;HK1 common genes common pathways 15453:[DB04833 DB04858] DB04833|Methaqualone CYP3A4 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 15454:[DB04833 DB03348] DB04833|Methaqualone CYP3A4 DB03348|Huperzine B ACHE common genes common pathways 15455:[DB04833 DB05930] DB04833|Methaqualone CYP3A4 DB05930|SB-559448 MPL common genes common pathways 15456:[DB04833 DB01864] DB04833|Methaqualone CYP3A4 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways 15457:[DB04833 DB05457] DB04833|Methaqualone CYP3A4 DB05457|OSI-7904L TYMS common genes common pathways 15458:[DB04833 DB02032] DB04833|Methaqualone CYP3A4 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 15459:[DB04833 DB04489] DB04833|Methaqualone CYP3A4 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 15460:[DB04833 DB11081] DB04833|Methaqualone CYP3A4 DB11081|Aluminum chloride GLUD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GLUD1 15461:[DB04833 DB09295] DB04833|Methaqualone CYP3A4 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 15462:[DB04833 DB00328] DB04833|Methaqualone CYP3A4 DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C19;CYP2C9;UGT1A9;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;AKR1C3;CYP2C19;CYP2C9;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process PTGS1;ABCC4;PTGR2;PTGS2;AKR1C3;CYP3A4;CYP2C19;CYP2C9 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;UGT1A9;CYP2C9;PTGS1;CES1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PPARA;PTGS2;UGT2B7;PTGS1;PPARG;CYP2C9;PLA2G2A GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0042737| drug catabolic process CYP2C9;CYP3A4 15463:[DB04833 DB06011] DB04833|Methaqualone CYP3A4 DB06011|AMG-222 DPP4 common genes common pathways 15464:[DB04833 DB00811] DB04833|Methaqualone CYP3A4 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;NT5C2 GO:0055114| oxidation-reduction process IMPDH2;CYP3A4;IMPDH1 15465:[DB04833 DB05395] DB04833|Methaqualone CYP3A4 DB05395|Amibegron ADRB3 common genes common pathways 15466:[DB04833 DB00577] DB04833|Methaqualone CYP3A4 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways 15467:[DB04833 DB00699] DB04833|Methaqualone CYP3A4 DB00699|Nicergoline ADRA1A;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 15468:[DB04833 DB05678] DB04833|Methaqualone CYP3A4 DB05678|SLx-4090 MTTP common genes common pathways GO:0006629| lipid metabolic process MTTP;CYP3A4 15469:[DB04833 DB01397] DB04833|Methaqualone CYP3A4 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 15470:[DB04833 DB03283] DB04833|Methaqualone CYP3A4 DB03283|beta-L-fucose ACHE common genes common pathways 15471:[DB04833 DB01728] DB04833|Methaqualone CYP3A4 DB01728|3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-Glycerol RHO common genes common pathways 15472:[DB04833 DB02391] DB04833|Methaqualone CYP3A4 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways 15473:[DB04833 DB14498] DB04833|Methaqualone CYP3A4 DB14498|Potassium acetate ATP1A1 common genes common pathways 15474:[DB04833 DB05478] DB04833|Methaqualone CYP3A4 DB05478|Pradefovir Mesylate CYP3A4 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 15475:[DB04833 DB00456] DB04833|Methaqualone CYP3A4 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 15476:[DB04833 DB03214] DB04833|Methaqualone CYP3A4 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;IL4I1 15477:[DB04833 DB06987] DB04833|Methaqualone CYP3A4 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2E 15478:[DB04833 DB11623] DB04833|Methaqualone CYP3A4 DB11623|Candoxatrilat MME common genes common pathways 15479:[DB04833 DB02299] DB04833|Methaqualone CYP3A4 DB02299|Arginineamide KCNA4 common genes common pathways 15480:[DB04833 DB03062] DB04833|Methaqualone CYP3A4 DB03062|(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone NMT1;NMT1 common genes common pathways 15481:[DB04833 DB08799] DB04833|Methaqualone CYP3A4 DB08799|Antazoline HRH1 common genes common pathways 15482:[DB04833 DB03934] DB04833|Methaqualone CYP3A4 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways GO:0055114| oxidation-reduction process CYCS;CYP3A4 15483:[DB04833 DB06081] DB04833|Methaqualone CYP3A4 DB06081|Caplacizumab VWF common genes common pathways 15484:[DB04833 DB12637] DB04833|Methaqualone CYP3A4 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways 15485:[DB04833 DB07000] DB04833|Methaqualone CYP3A4 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways 15486:[DB04833 DB07070] DB04833|Methaqualone CYP3A4 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways GO:0006629| lipid metabolic process PPARD;CYP3A4 15487:[DB04833 DB05447] DB04833|Methaqualone CYP3A4 DB05447|AVI-4557 HNF4A common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;HNF4A GO:0006629| lipid metabolic process HNF4A;CYP3A4 15488:[DB04833 DB00982] DB04833|Methaqualone CYP3A4 DB00982|Isotretinoin RARA common genes common pathways 15489:[DB04833 DB05107] DB04833|Methaqualone CYP3A4 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways GO:0055114| oxidation-reduction process G6PD;CYP3A4 GO:0006629| lipid metabolic process G6PD;CYP3A4 15490:[DB04833 DB01990] DB04833|Methaqualone CYP3A4 DB01990|Cholesterol sulfate RORA common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;RORA 15491:[DB04833 DB03682] DB04833|Methaqualone CYP3A4 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways 15492:[DB04833 DB02868] DB04833|Methaqualone CYP3A4 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways 15493:[DB04833 DB01328] DB04833|Methaqualone CYP3A4 DB01328|Cefonicid mrcA;ALB common genes common pathways 15494:[DB04833 DB13178] DB04833|Methaqualone CYP3A4 DB13178|Inositol SLC5A3 common genes common pathways 15495:[DB04833 DB12670] DB04833|Methaqualone CYP3A4 DB12670|Rolofylline ADORA1 common genes common pathways 15496:[DB04833 DB05243] DB04833|Methaqualone CYP3A4 DB05243|XL019 JAK2 common genes common pathways 15497:[DB04833 DB11692] DB04833|Methaqualone CYP3A4 DB11692|Pavinetant TACR3 common genes common pathways 15498:[DB04833 DB07157] DB04833|Methaqualone CYP3A4 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways 15499:[DB04833 DB01404] DB04833|Methaqualone CYP3A4 DB01404|Ginseng IL6;PTGS2;AHR common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;AHR GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 15500:[DB04833 DB08006] DB04833|Methaqualone CYP3A4 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 15501:[DB04833 DB06735] DB04833|Methaqualone CYP3A4 DB06735|Enclomiphene CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 15502:[DB04833 DB01364] DB04833|Methaqualone CYP3A4 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways 15503:[DB04833 DB04682] DB04833|Methaqualone CYP3A4 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 15504:[DB04833 DB06997] DB04833|Methaqualone CYP3A4 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways 15505:[DB04833 DB05464] DB04833|Methaqualone CYP3A4 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways 15506:[DB04833 DB04381] DB04833|Methaqualone CYP3A4 DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP3A4 15507:[DB04833 DB01644] DB04833|Methaqualone CYP3A4 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways GO:0055114| oxidation-reduction process GSR;CYP3A4 15508:[DB04833 DB03991] DB04833|Methaqualone CYP3A4 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;NEU2 15509:[DB04833 DB08350] DB04833|Methaqualone CYP3A4 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways 15510:[DB04833 DB08743] DB04833|Methaqualone CYP3A4 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways 15511:[DB04833 DB05200] DB04833|Methaqualone CYP3A4 DB05200|AT2220 GAA common genes common pathways 15512:[DB04833 DB14707] DB04833|Methaqualone CYP3A4 DB14707|Cemiplimab PDCD1 common genes common pathways 15513:[DB04833 DB12960] DB04833|Methaqualone CYP3A4 DB12960|INCB-9471 CCR5 common genes common pathways 15514:[DB04833 DB09333] DB04833|Methaqualone CYP3A4 DB09333|Iopodic acid DIO3;ALB common genes common pathways GO:0055114| oxidation-reduction process DIO3;CYP3A4 15515:[DB04833 DB06707] DB04833|Methaqualone CYP3A4 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways 15516:[DB04833 DB00293] DB04833|Methaqualone CYP3A4 DB00293|Raltitrexed TYMS;FPGS common genes common pathways 15517:[DB04833 DB07602] DB04833|Methaqualone CYP3A4 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways 15518:[DB04833 DB08818] DB04833|Methaqualone CYP3A4 DB08818|Hyaluronic acid CD44;ICAM1;HMMR;NCAN;VCAN;C1QBP;HAPLN1;HAPLN3;HAPLN4;HABP2;LAYN;STAB2;TNFAIP6;IMPG2;HABP4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;STAB2 15519:[DB04833 DB07609] DB04833|Methaqualone CYP3A4 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4 GO:0008202| steroid metabolic process CYP2A6;CYP3A4 GO:0017144| drug metabolic process CYP2A6;CYP3A4 15520:[DB04833 DB04617] DB04833|Methaqualone CYP3A4 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways 15521:[DB04833 DB00576] DB04833|Methaqualone CYP3A4 DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 15522:[DB04833 DB01213] DB04833|Methaqualone CYP3A4 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CAT;ADH1C;CYP3A4;CYP2E1;CYP2A6;ADH1A;ADH1B GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process ADH1A;CYP2A6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2E1 15523:[DB04833 DB00718] DB04833|Methaqualone CYP3A4 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;CYP3A4 15524:[DB04833 DB04463] DB04833|Methaqualone CYP3A4 DB04463|3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol CBR1;CBR1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CBR1 GO:0017144| drug metabolic process CYP3A4;CBR1 15525:[DB04833 DB00368] DB04833|Methaqualone CYP3A4 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0055114| oxidation-reduction process PAH;CYP3A4 15526:[DB04833 DB08238] DB04833|Methaqualone CYP3A4 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways 15527:[DB04833 DB00151] DB04833|Methaqualone CYP3A4 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process CBS;CYP3A4;CDO1 15528:[DB04833 DB02751] DB04833|Methaqualone CYP3A4 DB02751|Glycocyamine GAMT common genes common pathways 15529:[DB04833 DB03185] DB04833|Methaqualone CYP3A4 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 15530:[DB04833 DB03453] DB04833|Methaqualone CYP3A4 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways 15531:[DB04833 DB09292] DB04833|Methaqualone CYP3A4 DB09292|Sacubitril MME;SLCO1B1;SLCO1B3 common genes common pathways 15532:[DB04833 DB08024] DB04833|Methaqualone CYP3A4 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways 15533:[DB04833 DB09038] DB04833|Methaqualone CYP3A4 DB09038|Empagliflozin SLC5A2 common genes common pathways 15534:[DB04833 DB07586] DB04833|Methaqualone CYP3A4 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways 15535:[DB04833 DB00074] DB04833|Methaqualone CYP3A4 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways 15536:[DB04833 DB03516] DB04833|Methaqualone CYP3A4 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0055114| oxidation-reduction process AOX1;DPYD;CYP3A4;XDH GO:0017144| drug metabolic process AOX1;CYP3A4 15537:[DB04833 DB00749] DB04833|Methaqualone CYP3A4 DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PTGS2;CYP3A4;UGT2B7;PTGS1 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C9;PTGS1;CYP3A4 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;PTGS2;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C9;UGT1A9;CYP3A4;UGT1A10;UGT1A3 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 15538:[DB04833 DB03128] DB04833|Methaqualone CYP3A4 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways 15539:[DB04833 DB01306] DB04833|Methaqualone CYP3A4 DB01306|Insulin Aspart INSR common genes common pathways 15540:[DB04833 DB02198] DB04833|Methaqualone CYP3A4 DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 15541:[DB04833 DB00148] DB04833|Methaqualone CYP3A4 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways 15542:[DB04833 DB07780] DB04833|Methaqualone CYP3A4 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 15543:[DB04833 DB06090] DB04833|Methaqualone CYP3A4 DB06090|Bradanicline CHRNA7 common genes common pathways 15544:[DB04833 DB13151] DB04833|Methaqualone CYP3A4 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;F8 15545:[DB04833 DB01610] DB04833|Methaqualone CYP3A4 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways 15546:[DB04833 DB11914] DB04833|Methaqualone CYP3A4 DB11914|Lebrikizumab IL13;IL13 common genes common pathways 15547:[DB04833 DB01382] DB04833|Methaqualone CYP3A4 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways 15548:[DB04833 DB08836] DB04833|Methaqualone CYP3A4 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways 15549:[DB04833 DB00165] DB04833|Methaqualone CYP3A4 DB00165|Pyridoxine PDXK;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0055114| oxidation-reduction process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0002933| CYP3A4;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 15550:[DB04833 DB01600] DB04833|Methaqualone CYP3A4 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4 15551:[DB04833 DB06843] DB04833|Methaqualone CYP3A4 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways 15552:[DB04833 DB08675] DB04833|Methaqualone CYP3A4 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways GO:0006629| lipid metabolic process PTGIS;CYP3A4 GO:0055114| oxidation-reduction process PTGIS;CYP3A4 15553:[DB04833 DB00039] DB04833|Methaqualone CYP3A4 DB00039|Palifermin FGFR2;NRP1;FGFR1;FGFR4;FGFR3;HSPG2 common genes common pathways GO:0006629| lipid metabolic process HSPG2;CYP3A4 15554:[DB04833 DB06699] DB04833|Methaqualone CYP3A4 DB06699|Degarelix GNRHR common genes common pathways 15555:[DB04833 DB04972] DB04833|Methaqualone CYP3A4 DB04972|Canfosfamide GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1 15556:[DB04833 DB06822] DB04833|Methaqualone CYP3A4 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways 15557:[DB04833 DB00200] DB04833|Methaqualone CYP3A4 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;CUBN GO:0008202| steroid metabolic process CUBN;CYP3A4 GO:0055114| oxidation-reduction process MMACHC;MTRR;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CUBN 15558:[DB04833 DB09564] DB04833|Methaqualone CYP3A4 DB09564|Insulin Degludec INSR common genes common pathways 15559:[DB04833 DB14517] DB04833|Methaqualone CYP3A4 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways 15560:[DB04833 DB01212] DB04833|Methaqualone CYP3A4 DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 15561:[DB04833 DB08166] DB04833|Methaqualone CYP3A4 DB08166|(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile PIM1 common genes common pathways 15562:[DB04833 DB06931] DB04833|Methaqualone CYP3A4 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 15563:[DB04833 DB01289] DB04833|Methaqualone CYP3A4 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 15564:[DB04833 DB08176] DB04833|Methaqualone CYP3A4 DB08176|(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOB 15565:[DB04833 DB13144] DB04833|Methaqualone CYP3A4 DB13144|Lenograstim CSF3R common genes common pathways 15566:[DB04833 DB06191] DB04833|Methaqualone CYP3A4 DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways 15567:[DB04833 DB08104] DB04833|Methaqualone CYP3A4 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways 15568:[DB04833 DB00884] DB04833|Methaqualone CYP3A4 DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 15569:[DB04833 DB01014] DB04833|Methaqualone CYP3A4 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;ALOX5;PTGS2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 15570:[DB04833 DB04334] DB04833|Methaqualone CYP3A4 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;AOC3 GO:0055114| oxidation-reduction process AOC3;CYP3A4 15571:[DB04833 DB14041] DB04833|Methaqualone CYP3A4 DB14041|Fremanezumab CALCA;CALCB common genes common pathways 15572:[DB04833 DB05265] DB04833|Methaqualone CYP3A4 DB05265|Ecabet NOXO1;ureC common genes common pathways GO:0055114| oxidation-reduction process NOXO1;CYP3A4 15573:[DB04833 DB05479] DB04833|Methaqualone CYP3A4 DB05479|CZEN 002 MC1R common genes common pathways 15574:[DB04833 DB00993] DB04833|Methaqualone CYP3A4 DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;XDH;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 15575:[DB04833 DB01056] DB04833|Methaqualone CYP3A4 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 15576:[DB04833 DB04876] DB04833|Methaqualone CYP3A4 DB04876|Vildagliptin DPP4 common genes common pathways 15577:[DB04833 DB08057] DB04833|Methaqualone CYP3A4 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways 15578:[DB04833 DB11077] DB04833|Methaqualone CYP3A4 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0008202| steroid metabolic process SULT1A1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;SULT1A1 GO:0006805| xenobiotic metabolic process CYP3A4;SULT1A1 GO:0055114| oxidation-reduction process ADH5;CYP3A4;CYP4A11 15579:[DB04833 DB11093] DB04833|Methaqualone CYP3A4 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways 15580:[DB04833 DB08358] DB04833|Methaqualone CYP3A4 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 15581:[DB04833 DB11948] DB04833|Methaqualone CYP3A4 DB11948|Lapachone RBP3 common genes common pathways GO:0006629| lipid metabolic process RBP3;CYP3A4 15582:[DB04833 DB01255] DB04833|Methaqualone CYP3A4 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 15583:[DB04833 DB07004] DB04833|Methaqualone CYP3A4 DB07004|2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide S100B common genes common pathways 15584:[DB04833 DB04327] DB04833|Methaqualone CYP3A4 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTEN 15585:[DB04833 DB08688] DB04833|Methaqualone CYP3A4 DB08688|undecan-2-one ACOT13 common genes common pathways 15586:[DB04833 DB06880] DB04833|Methaqualone CYP3A4 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways 15587:[DB04833 DB04263] DB04833|Methaqualone CYP3A4 DB04263|Geneticin ODC1 common genes common pathways 15588:[DB04833 DB08693] DB04833|Methaqualone CYP3A4 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 15589:[DB04833 DB00127] DB04833|Methaqualone CYP3A4 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process SMOX;XDH;CYP3A4 15590:[DB04833 DB06420] DB04833|Methaqualone CYP3A4 DB06420|Annamycin TOP2A common genes common pathways 15591:[DB04833 DB07382] DB04833|Methaqualone CYP3A4 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways 15592:[DB04833 DB01712] DB04833|Methaqualone CYP3A4 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways 15593:[DB04833 DB00547] DB04833|Methaqualone CYP3A4 DB00547|Desoximetasone NR3C1 common genes common pathways 15594:[DB04833 DB00868] DB04833|Methaqualone CYP3A4 DB00868|Benzonatate SCN5A common genes common pathways 15595:[DB04833 DB07795] DB04833|Methaqualone CYP3A4 DB07795|Fisetin CDK6 common genes common pathways 15596:[DB04833 DB09103] DB04833|Methaqualone CYP3A4 DB09103|Ancestim KIT common genes common pathways 15597:[DB04833 DB12731] DB04833|Methaqualone CYP3A4 DB12731|Daporinad NAMPT common genes common pathways 15598:[DB04833 DB07201] DB04833|Methaqualone CYP3A4 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways 15599:[DB04833 DB05446] DB04833|Methaqualone CYP3A4 DB05446|LJP 1082 APOH common genes common pathways 15600:[DB04833 DB04573] DB04833|Methaqualone CYP3A4 DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 15601:[DB04833 DB06963] DB04833|Methaqualone CYP3A4 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways 15602:[DB04833 DB00893] DB04833|Methaqualone CYP3A4 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;FTH1 15603:[DB04833 DB00128] DB04833|Methaqualone CYP3A4 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CAD GO:0006805| xenobiotic metabolic process CYP3A4;ACY1;ACY3 GO:0055114| oxidation-reduction process CYP3A4;ASPH 15604:[DB04833 DB06321] DB04833|Methaqualone CYP3A4 DB06321|R-348 JAK3 common genes common pathways 15605:[DB04833 DB02281] DB04833|Methaqualone CYP3A4 DB02281|Formycin MTAP common genes common pathways 15606:[DB04833 DB02598] DB04833|Methaqualone CYP3A4 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0055114| oxidation-reduction process PAM;CYP3A4 15607:[DB04833 DB05209] DB04833|Methaqualone CYP3A4 DB05209|SYM001 RHD common genes common pathways 15608:[DB04833 DB14639] DB04833|Methaqualone CYP3A4 DB14639|Boldenone undecylenate AR common genes common pathways 15609:[DB04833 DB06802] DB04833|Methaqualone CYP3A4 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 15610:[DB04833 DB00797] DB04833|Methaqualone CYP3A4 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways 15611:[DB04833 DB00345] DB04833|Methaqualone CYP3A4 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1 15612:[DB04833 DB02783] DB04833|Methaqualone CYP3A4 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 15613:[DB04833 DB06444] DB04833|Methaqualone CYP3A4 DB06444|Dexanabinol TNF common genes common pathways 15614:[DB04833 DB05595] DB04833|Methaqualone CYP3A4 DB05595|Farletuzumab FOLR1 common genes common pathways 15615:[DB04833 DB08174] DB04833|Methaqualone CYP3A4 DB08174|5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways 15616:[DB04833 DB06103] DB04833|Methaqualone CYP3A4 DB06103|VX-148 IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process IMPDH1;IMPDH2;CYP3A4 15617:[DB04833 DB00061] DB04833|Methaqualone CYP3A4 DB00061|Pegademase bovine GRB2 common genes common pathways 15618:[DB04833 DB07002] DB04833|Methaqualone CYP3A4 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 15619:[DB04833 DB01113] DB04833|Methaqualone CYP3A4 DB01113|Papaverine PDE4B;PDE10A common genes common pathways 15620:[DB04833 DB07364] DB04833|Methaqualone CYP3A4 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways 15621:[DB04833 DB14072] DB04833|Methaqualone CYP3A4 DB14072|Reversin 121 ABCB1 common genes common pathways 15622:[DB04833 DB05758] DB04833|Methaqualone CYP3A4 DB05758|CYT007-TNFQb TNF common genes common pathways 15623:[DB04833 DB07081] DB04833|Methaqualone CYP3A4 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways 15624:[DB04833 DB06495] DB04833|Methaqualone CYP3A4 DB06495|Onercept TNF common genes common pathways 15625:[DB04833 DB01897] DB04833|Methaqualone CYP3A4 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HPGDS 15626:[DB04833 DB08067] DB04833|Methaqualone CYP3A4 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways 15627:[DB04833 DB11278] DB04833|Methaqualone CYP3A4 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways 15628:[DB04833 DB02342] DB04833|Methaqualone CYP3A4 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0055114| oxidation-reduction process CYP1B1;CYP1A1;CYP19A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A4 GO:0002933| CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP1B1;CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A1 15629:[DB04833 DB14502] DB04833|Methaqualone CYP3A4 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways 15630:[DB04833 DB02417] DB04833|Methaqualone CYP3A4 DB02417|2,4,6-Tribromophenol TTR common genes common pathways 15631:[DB04833 DB07410] DB04833|Methaqualone CYP3A4 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways 15632:[DB04833 DB03542] DB04833|Methaqualone CYP3A4 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 15633:[DB04833 DB11979] DB04833|Methaqualone CYP3A4 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes CYP3A4 common pathways GO:0002933| CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP2C8;CYP2D6;CYP3A5 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2D6;CYP3A43;CYP3A4;CYP3A7 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2D6;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006706| steroid catabolic process CYP3A4 15634:[DB04833 DB06510] DB04833|Methaqualone CYP3A4 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PPARA;PPARG GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A3;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A2;CYP3A4 GO:0002933| CYP2C8;CYP3A4 15635:[DB04833 DB00507] DB04833|Methaqualone CYP3A4 DB00507|Nitazoxanide SLC19A1 common genes common pathways 15636:[DB04833 DB07776] DB04833|Methaqualone CYP3A4 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1B1 GO:0008202| steroid metabolic process CYP1B1;CYP3A4 15637:[DB04833 DB06689] DB04833|Methaqualone CYP3A4 DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 15638:[DB04833 DB00922] DB04833|Methaqualone CYP3A4 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0006629| lipid metabolic process PDE3A;CYP3A4 15639:[DB04833 DB09328] DB04833|Methaqualone CYP3A4 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process ELOVL4;FADS1;ACAA1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;FADS1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 15640:[DB04833 DB03597] DB04833|Methaqualone CYP3A4 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways 15641:[DB04833 DB04857] DB04833|Methaqualone CYP3A4 DB04857|Brasofensine DRD2 common genes common pathways 15642:[DB04833 DB02661] DB04833|Methaqualone CYP3A4 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways 15643:[DB04833 DB08229] DB04833|Methaqualone CYP3A4 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways 15644:[DB04833 DB02079] DB04833|Methaqualone CYP3A4 DB02079|Aminooxyacetic acid AGXT common genes common pathways 15645:[DB04833 DB05524] DB04833|Methaqualone CYP3A4 DB05524|Pelitinib EGFR common genes common pathways 15646:[DB04833 DB00784] DB04833|Methaqualone CYP3A4 DB00784|Mefenamic acid PTGS2;PTGS1;CYP2C9;CYP2C8;UGT1A9;ALB common genes common pathways GO:0002933| CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;UGT1A9;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;PTGS1;PTGS2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C8 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C9;UGT1A9;CYP2C8 15647:[DB04833 DB11155] DB04833|Methaqualone CYP3A4 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A4 GO:0055114| oxidation-reduction process CYP1B1;CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1B1;CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A1 GO:0002933| CYP3A4;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 15648:[DB04833 DB00348] DB04833|Methaqualone CYP3A4 DB00348|Nitisinone HPD common genes common pathways GO:0055114| oxidation-reduction process HPD;CYP3A4 15649:[DB04833 DB11644] DB04833|Methaqualone CYP3A4 DB11644|Tafamidis TTR common genes common pathways 15650:[DB04833 DB11751] DB04833|Methaqualone CYP3A4 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways 15651:[DB04833 DB02076] DB04833|Methaqualone CYP3A4 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PGD 15652:[DB04833 DB01203] DB04833|Methaqualone CYP3A4 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 15653:[DB04833 DB08373] DB04833|Methaqualone CYP3A4 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways 15654:[DB04833 DB01048] DB04833|Methaqualone CYP3A4 DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0055114| oxidation-reduction process ADH6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 15655:[DB04833 DB06475] DB04833|Methaqualone CYP3A4 DB06475|Ruplizumab CD40LG common genes common pathways 15656:[DB04833 DB04912] DB04833|Methaqualone CYP3A4 DB04912|Stannsoporfin HMOX1;HMOX2 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP3A4;HMOX2 15657:[DB04833 DB11090] DB04833|Methaqualone CYP3A4 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 15658:[DB04833 DB01097] DB04833|Methaqualone CYP3A4 DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;AHR;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process DHODH;CYP1A2;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C9 15659:[DB04833 DB00670] DB04833|Methaqualone CYP3A4 DB00670|Pirenzepine CHRM1 common genes common pathways 15660:[DB04833 DB04878] DB04833|Methaqualone CYP3A4 DB04878|Voglibose MGAM common genes common pathways 15661:[DB04833 DB00113] DB04833|Methaqualone CYP3A4 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways 15662:[DB04833 DB11132] DB04833|Methaqualone CYP3A4 DB11132|Silicon dioxide MARCO common genes common pathways 15663:[DB04833 DB00311] DB04833|Methaqualone CYP3A4 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways 15664:[DB04833 DB00308] DB04833|Methaqualone CYP3A4 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways 15665:[DB04833 DB09237] DB04833|Methaqualone CYP3A4 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;NOS2;NOS3 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 15666:[DB04833 DB04368] DB04833|Methaqualone CYP3A4 DB04368|Bb-3497 def;PDF common genes common pathways 15667:[DB04833 DB04214] DB04833|Methaqualone CYP3A4 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 15668:[DB04833 DB05382] DB04833|Methaqualone CYP3A4 DB05382|Iodine MT-ND5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MT-ND5 15669:[DB04833 DB02490] DB04833|Methaqualone CYP3A4 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 15670:[DB04833 DB02106] DB04833|Methaqualone CYP3A4 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways 15671:[DB04833 DB07702] DB04833|Methaqualone CYP3A4 DB07702|17alpha-Estriol NCOA5;ESR2 common genes common pathways 15672:[DB04833 DB04348] DB04833|Methaqualone CYP3A4 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0006629| lipid metabolic process CEL;FABP6;SLC16A1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;ABCC4 15673:[DB04833 DB08035] DB04833|Methaqualone CYP3A4 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways 15674:[DB04833 DB03338] DB04833|Methaqualone CYP3A4 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARD 15675:[DB04833 DB07354] DB04833|Methaqualone CYP3A4 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways 15676:[DB04833 DB04895] DB04833|Methaqualone CYP3A4 DB04895|Pegaptanib NRP1 common genes common pathways 15677:[DB04833 DB14581] DB04833|Methaqualone CYP3A4 DB14581|CPI-1205 EZH2 common genes common pathways 15678:[DB04833 DB14499] DB04833|Methaqualone CYP3A4 DB14499|Potassium sulfate ATP1A1 common genes common pathways 15679:[DB04833 DB06695] DB04833|Methaqualone CYP3A4 DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process NQO2;CYP3A4 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0006805| xenobiotic metabolic process CES2;UGT1A9;NQO2;UGT2B15;CYP3A4;CES1 GO:0006629| lipid metabolic process CYP3A4;UGT2B7 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;UGT2B15 GO:0017144| drug metabolic process UGT1A9;CYP3A4 15680:[DB04833 DB04661] DB04833|Methaqualone CYP3A4 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways 15681:[DB04833 DB02343] DB04833|Methaqualone CYP3A4 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways 15682:[DB04833 DB08819] DB04833|Methaqualone CYP3A4 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 15683:[DB04833 DB00627] DB04833|Methaqualone CYP3A4 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process SLC16A1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 15684:[DB04833 DB00050] DB04833|Methaqualone CYP3A4 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways 15685:[DB04833 DB06732] DB04833|Methaqualone CYP3A4 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP1B1 GO:0006805| xenobiotic metabolic process AHR;CYP1B1;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1B1;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4;ESR1 15686:[DB04833 DB05983] DB04833|Methaqualone CYP3A4 DB05983|Bardoxolone methyl NFKBIA common genes common pathways 15687:[DB04833 DB09336] DB04833|Methaqualone CYP3A4 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways 15688:[DB04833 DB09532] DB04833|Methaqualone CYP3A4 DB09532|Secretin human SCTR common genes common pathways 15689:[DB04833 DB04100] DB04833|Methaqualone CYP3A4 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways 15690:[DB04833 DB03041] DB04833|Methaqualone CYP3A4 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 15691:[DB04833 DB03556] DB04833|Methaqualone CYP3A4 DB03556|2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 CBR1;CBR1 common genes common pathways GO:0055114| oxidation-reduction process CBR1;CYP3A4 GO:0017144| drug metabolic process CBR1;CYP3A4 15692:[DB04833 DB00126] DB04833|Methaqualone CYP3A4 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0055114| oxidation-reduction process PLOD3;DBH;ALKBH2;KDM5D;P3H2;PLOD1;PLOD2;ALKBH3;P3H3;CYP3A4;TMLHE;EGLN2;OGFOD1;P4HA1;P3H1;BBOX1;EGLN1;EGLN3;PAM;OGFOD2;P4HTM;PHYH GO:0070989| oxidative demethylation CYP3A4;ALKBH2 15693:[DB04833 DB01274] DB04833|Methaqualone CYP3A4 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP2A6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2A6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2C9;CYP2D6;CYP2C19 15694:[DB04833 DB03442] DB04833|Methaqualone CYP3A4 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways 15695:[DB04833 DB09413] DB04833|Methaqualone CYP3A4 DB09413|Monopotassium phosphate ALPI common genes common pathways 15696:[DB04833 DB06360] DB04833|Methaqualone CYP3A4 DB06360|Lucatumumab CD40 common genes common pathways 15697:[DB04833 DB00035] DB04833|Methaqualone CYP3A4 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 15698:[DB04833 DB02745] DB04833|Methaqualone CYP3A4 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 15699:[DB04833 DB11660] DB04833|Methaqualone CYP3A4 DB11660|Latanoprostene Bunod PTGFR;SLCO2B1 common genes common pathways 15700:[DB04833 DB09217] DB04833|Methaqualone CYP3A4 DB09217|Firocoxib PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 15701:[DB04833 DB00430] DB04833|Methaqualone CYP3A4 DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways 15702:[DB04833 DB05017] DB04833|Methaqualone CYP3A4 DB05017|YSIL6 TNF;IL6 common genes common pathways 15703:[DB04833 DB03506] DB04833|Methaqualone CYP3A4 DB03506|9-Deazaadenine APRT common genes common pathways 15704:[DB04833 DB03455] DB04833|Methaqualone CYP3A4 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways 15705:[DB04833 DB12119] DB04833|Methaqualone CYP3A4 DB12119|Gevokizumab IL1B common genes common pathways 15706:[DB04833 DB07617] DB04833|Methaqualone CYP3A4 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP3A4;CYP2A6 15707:[DB04833 DB00081] DB04833|Methaqualone CYP3A4 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 15708:[DB04833 DB02587] DB04833|Methaqualone CYP3A4 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes common pathways 15709:[DB04833 DB08049] DB04833|Methaqualone CYP3A4 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways 15710:[DB04833 DB03040] DB04833|Methaqualone CYP3A4 DB03040|Nitrilotriacetic Acid LTF common genes common pathways 15711:[DB04833 DB01330] DB04833|Methaqualone CYP3A4 DB01330|Cefotetan ALB common genes common pathways 15712:[DB04833 DB06549] DB04833|Methaqualone CYP3A4 DB06549|Labradimil BDKRB2 common genes common pathways 15713:[DB04833 DB01043] DB04833|Methaqualone CYP3A4 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2B6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C19;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP2B6;CYP2C19;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2B6;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2B6;CYP2C19 15714:[DB04833 DB09472] DB04833|Methaqualone CYP3A4 DB09472|Sodium sulfate CA2;CA1 common genes common pathways 15715:[DB04833 DB00968] DB04833|Methaqualone CYP3A4 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways 15716:[DB04833 DB02405] DB04833|Methaqualone CYP3A4 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways 15717:[DB04833 DB08952] DB04833|Methaqualone CYP3A4 DB08952|Indenolol CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 15718:[DB04833 DB02010] DB04833|Methaqualone CYP3A4 DB02010|Staurosporine LCK;PIM1;ITK;SYK;MAPKAPK2;GSK3B;CSK;CDK2;PIK3CG;PDPK1;PRKCQ;ZAP70;CHRM1;ABCB1 common genes common pathways 15719:[DB04833 DB09035] DB04833|Methaqualone CYP3A4 DB09035|Nivolumab PDCD1 common genes common pathways 15720:[DB04833 DB12159] DB04833|Methaqualone CYP3A4 DB12159|Dupilumab IL4R common genes common pathways 15721:[DB04833 DB08770] DB04833|Methaqualone CYP3A4 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways 15722:[DB04833 DB02900] DB04833|Methaqualone CYP3A4 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways 15723:[DB04833 DB00424] DB04833|Methaqualone CYP3A4 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 15724:[DB04833 DB09535] DB04833|Methaqualone CYP3A4 DB09535|Octocrylene ESR1;ESR2 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 15725:[DB04833 DB04021] DB04833|Methaqualone CYP3A4 DB04021|MF268 ACHE common genes common pathways 15726:[DB04833 DB09045] DB04833|Methaqualone CYP3A4 DB09045|Dulaglutide GLP1R common genes common pathways 15727:[DB04833 DB06307] DB04833|Methaqualone CYP3A4 DB06307|Apoptone BCL2 common genes common pathways 15728:[DB04833 DB09105] DB04833|Methaqualone CYP3A4 DB09105|Asfotase Alfa S1PR1 common genes common pathways 15729:[DB04833 DB09299] DB04833|Methaqualone CYP3A4 DB09299|Tenofovir alafenamide pol;ABCB1 common genes common pathways 15730:[DB04833 DB12130] DB04833|Methaqualone CYP3A4 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0002933| CYP3A4;CYP3A5;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;CYP2B6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A3;CYP2B6;CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP3A5;CYP2C19;CYP2C8;CYP2B6 GO:0042738| exogenous drug catabolic process CYP2B6;CYP2C8;CYP2C19;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2B6;CYP3A5;CYP2C19;CYP2C8 15731:[DB04833 DB06325] DB04833|Methaqualone CYP3A4 DB06325|Pegpleranib PDGFB common genes common pathways 15732:[DB04833 DB07286] DB04833|Methaqualone CYP3A4 DB07286|BMS-564929 AR common genes common pathways 15733:[DB04833 DB04620] DB04833|Methaqualone CYP3A4 DB04620|Cycloleucine GRIN1 common genes common pathways 15734:[DB04833 DB01332] DB04833|Methaqualone CYP3A4 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways 15735:[DB04833 DB07344] DB04833|Methaqualone CYP3A4 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways GO:0006629| lipid metabolic process MCAT;CYP3A4 15736:[DB04833 DB06688] DB04833|Methaqualone CYP3A4 DB06688|Sipuleucel-T ACPP common genes common pathways 15737:[DB04833 DB07394] DB04833|Methaqualone CYP3A4 DB07394|AUROVERTIN B ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 15738:[DB04833 DB05192] DB04833|Methaqualone CYP3A4 DB05192|MB07811 THRB common genes common pathways 15739:[DB04833 DB04519] DB04833|Methaqualone CYP3A4 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARA 15740:[DB04833 DB00322] DB04833|Methaqualone CYP3A4 DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 15741:[DB04833 DB03664] DB04833|Methaqualone CYP3A4 DB03664|UP5 CMPK1 common genes common pathways 15742:[DB04833 DB08088] DB04833|Methaqualone CYP3A4 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways 15743:[DB04833 DB06650] DB04833|Methaqualone CYP3A4 DB06650|Ofatumumab MS4A1 common genes common pathways 15744:[DB04833 DB04409] DB04833|Methaqualone CYP3A4 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways 15745:[DB04833 DB08560] DB04833|Methaqualone CYP3A4 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 15746:[DB04833 DB07917] DB04833|Methaqualone CYP3A4 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 15747:[DB04833 DB03384] DB04833|Methaqualone CYP3A4 DB03384|Fica CASP7 common genes common pathways 15748:[DB04833 DB07630] DB04833|Methaqualone CYP3A4 DB07630|N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways 15749:[DB04833 DB00931] DB04833|Methaqualone CYP3A4 DB00931|Metacycline ALB common genes common pathways 15750:[DB04833 DB05233] DB04833|Methaqualone CYP3A4 DB05233|AP1081 ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 15751:[DB04833 DB00903] DB04833|Methaqualone CYP3A4 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP3A4 15752:[DB04833 DB07789] DB04833|Methaqualone CYP3A4 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways 15753:[DB04833 DB06945] DB04833|Methaqualone CYP3A4 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways 15754:[DB04833 DB02328] DB04833|Methaqualone CYP3A4 DB02328|2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid CTH common genes common pathways 15755:[DB04833 DB04491] DB04833|Methaqualone CYP3A4 DB04491|Diisopropylphosphono Group CFB;DPP4 common genes common pathways 15756:[DB04833 DB01089] DB04833|Methaqualone CYP3A4 DB01089|Deserpidine SLC18A2 common genes common pathways 15757:[DB04833 DB13166] DB04833|Methaqualone CYP3A4 DB13166|Zofenopril ACE common genes common pathways 15758:[DB04833 DB00861] DB04833|Methaqualone CYP3A4 DB00861|Diflunisal PTGS2;PTGS1;UGT1A8;UGT1A9;TTR;ALB;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process UGT1A9;CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0008202| steroid metabolic process CYP3A4;UGT1A8 GO:0017144| drug metabolic process UGT1A9;UGT1A8;CYP3A4 15759:[DB04833 DB00995] DB04833|Methaqualone CYP3A4 DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PRDX5 15760:[DB04833 DB00108] DB04833|Methaqualone CYP3A4 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways 15761:[DB04833 DB08930] DB04833|Methaqualone CYP3A4 DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes CYP3A4 common pathways GO:0002933| CYP3A4;CYP3A7;CYP3A5 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;UGT1A1;CYP3A5 GO:0070989| oxidative demethylation CYP3A5;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A3;UGT1A9;UGT1A1 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP3A7;CYP3A43 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;UGT1A9;CYP3A4;CYP3A7 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 15762:[DB04833 DB11858] DB04833|Methaqualone CYP3A4 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways 15763:[DB04833 DB14132] DB04833|Methaqualone CYP3A4 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 15764:[DB04833 DB09070] DB04833|Methaqualone CYP3A4 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;STS;SULT1A1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0055114| oxidation-reduction process HSD3B1;HSD3B2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;STS;SULT1A1 GO:0006706| steroid catabolic process CYP3A4;STS GO:0006805| xenobiotic metabolic process SULT1A1;CYP3A4 15765:[DB04833 DB02462] DB04833|Methaqualone CYP3A4 DB02462|Thiocoumarin NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 15766:[DB04833 DB02395] DB04833|Methaqualone CYP3A4 DB02395|3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol NQO1 common genes common pathways GO:0055114| oxidation-reduction process NQO1;CYP3A4 GO:0006805| xenobiotic metabolic process NQO1;CYP3A4 15767:[DB04833 DB00964] DB04833|Methaqualone CYP3A4 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways 15768:[DB04833 DB00487] DB04833|Methaqualone CYP3A4 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 15769:[DB04833 DB07154] DB04833|Methaqualone CYP3A4 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways 15770:[DB04833 DB13881] DB04833|Methaqualone CYP3A4 DB13881|Tisagenlecleucel CD19 common genes common pathways 15771:[DB04833 DB03703] DB04833|Methaqualone CYP3A4 DB03703|Cyclohexanol ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;CYP3A4 15772:[DB04833 DB09203] DB04833|Methaqualone CYP3A4 DB09203|Synephrine ADRA1A;ADRA1B;ADRA1D common genes common pathways 15773:[DB04833 DB13132] DB04833|Methaqualone CYP3A4 DB13132|Artemisinin CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP2B6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2B6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2B6 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4 15774:[DB04833 DB04852] DB04833|Methaqualone CYP3A4 DB04852|Implitapide MTTP common genes common pathways GO:0006629| lipid metabolic process CYP3A4;MTTP 15775:[DB04833 DB05920] DB04833|Methaqualone CYP3A4 DB05920|RTA 744 TOP2A common genes common pathways 15776:[DB04833 DB03894] DB04833|Methaqualone CYP3A4 DB03894|N-Propargyl-1(S)-Aminoindan MAOB;MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOB 15777:[DB04833 DB05938] DB04833|Methaqualone CYP3A4 DB05938|Edonerpic APP common genes common pathways 15778:[DB04833 DB12610] DB04833|Methaqualone CYP3A4 DB12610|Ebselen EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP3A4 GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4 15779:[DB04833 DB11397] DB04833|Methaqualone CYP3A4 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways 15780:[DB04833 DB00600] DB04833|Methaqualone CYP3A4 DB00600|Monobenzone TYR common genes common pathways GO:0055114| oxidation-reduction process TYR;CYP3A4 15781:[DB04833 DB03889] DB04833|Methaqualone CYP3A4 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 15782:[DB04833 DB01831] DB04833|Methaqualone CYP3A4 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways 15783:[DB04833 DB14527] DB04833|Methaqualone CYP3A4 DB14527|Chromic nitrate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYB5A;CYP3A4 15784:[DB04833 DB08435] DB04833|Methaqualone CYP3A4 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 15785:[DB04833 DB06410] DB04833|Methaqualone CYP3A4 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0055114| oxidation-reduction process CYP27A1;CYP3A4 15786:[DB04833 DB01064] DB04833|Methaqualone CYP3A4 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0002933| CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 15787:[DB04833 DB03948] DB04833|Methaqualone CYP3A4 DB03948|6-Chloropurine Riboside, 5'-Monophosphate IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process IMPDH1;IMPDH2;CYP3A4 15788:[DB04833 DB06721] DB04833|Methaqualone CYP3A4 DB06721|Gimatecan SLCO1B1 common genes common pathways 15789:[DB04833 DB04853] DB04833|Methaqualone CYP3A4 DB04853|Binodenoson ADORA2A common genes common pathways 15790:[DB04833 DB02515] DB04833|Methaqualone CYP3A4 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways 15791:[DB04833 DB03486] DB04833|Methaqualone CYP3A4 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways 15792:[DB04833 DB14529] DB04833|Methaqualone CYP3A4 DB14529|Chromium nicotinate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYB5A;CYP3A4 15793:[DB04833 DB10772] DB04833|Methaqualone CYP3A4 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways 15794:[DB04833 DB02107] DB04833|Methaqualone CYP3A4 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 15795:[DB04833 DB08488] DB04833|Methaqualone CYP3A4 DB08488|4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE F10 common genes common pathways 15796:[DB04833 DB04256] DB04833|Methaqualone CYP3A4 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways 15797:[DB04833 DB06538] DB04833|Methaqualone CYP3A4 DB06538|Robalzotan HTR1A common genes common pathways 15798:[DB04833 DB08156] DB04833|Methaqualone CYP3A4 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways 15799:[DB04833 DB14002] DB04833|Methaqualone CYP3A4 DB14002|D-alpha-Tocopherol acetate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0008202| steroid metabolic process NR1I2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;NR1I2;NQO1;GSTP1 GO:0006629| lipid metabolic process CYP3A4;TTPA GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4 GO:0055114| oxidation-reduction process ALOX5;SOD1;CYP3A4;HMOX1;GSTO1;NQO1 15800:[DB04833 DB08190] DB04833|Methaqualone CYP3A4 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;NQO2 GO:0055114| oxidation-reduction process CYP3A4;NQO2 15801:[DB04833 DB08221] DB04833|Methaqualone CYP3A4 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways 15802:[DB04833 DB04578] DB04833|Methaqualone CYP3A4 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways 15803:[DB04833 DB01349] DB04833|Methaqualone CYP3A4 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 15804:[DB04833 DB11774] DB04833|Methaqualone CYP3A4 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 15805:[DB04833 DB04910] DB04833|Methaqualone CYP3A4 DB04910|Oxibendazole TUBB4B common genes common pathways 15806:[DB04833 DB08772] DB04833|Methaqualone CYP3A4 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;AKR1B10;AKR1B1 GO:0008202| steroid metabolic process AKR1B10;CYP3A4 15807:[DB04833 DB08222] DB04833|Methaqualone CYP3A4 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways GO:0006629| lipid metabolic process CLPS;CYP3A4;PNLIP 15808:[DB04833 DB01951] DB04833|Methaqualone CYP3A4 DB01951|Gpi-1046 FKBP1A common genes common pathways 15809:[DB04833 DB09154] DB04833|Methaqualone CYP3A4 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 15810:[DB04833 DB00140] DB04833|Methaqualone CYP3A4 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process BLVRB;CYP3A4;MAOA;MTHFR 15811:[DB04833 DB01231] DB04833|Methaqualone CYP3A4 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways 15812:[DB04833 DB00710] DB04833|Methaqualone CYP3A4 DB00710|Ibandronate FDPS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 15813:[DB04833 DB00144] DB04833|Methaqualone CYP3A4 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SMPD3;PTDSS2;PTDSS1;PISD 15814:[DB04833 DB00511] DB04833|Methaqualone CYP3A4 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways 15815:[DB04833 DB00917] DB04833|Methaqualone CYP3A4 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;CYP3A4;CYP11A1;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0006629| lipid metabolic process CYP3A4;CYP11A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1 GO:0008202| steroid metabolic process CYP3A4;CYP11A1 15816:[DB04833 DB00331] DB04833|Methaqualone CYP3A4 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0006629| lipid metabolic process PRKAB1;CYP3A4 15817:[DB04833 DB08353] DB04833|Methaqualone CYP3A4 DB08353|2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 15818:[DB04833 DB03292] DB04833|Methaqualone CYP3A4 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways 15819:[DB04833 DB07700] DB04833|Methaqualone CYP3A4 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0055114| oxidation-reduction process AKR1C3;CYP3A4 GO:0008202| steroid metabolic process AKR1C3;CYP3A4 15820:[DB04833 DB01271] DB04833|Methaqualone CYP3A4 DB01271|Idursulfase PLIN3 common genes common pathways 15821:[DB04833 DB07680] DB04833|Methaqualone CYP3A4 DB07680|[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID CMA1 common genes common pathways 15822:[DB04833 DB04951] DB04833|Methaqualone CYP3A4 DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 15823:[DB04833 DB04957] DB04833|Methaqualone CYP3A4 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP3A5 GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0002933| CYP3A5;CYP1A1;CYP3A4 GO:0036378| CYP3A4 15824:[DB04833 DB04919] DB04833|Methaqualone CYP3A4 DB04919|Alfimeprase FGA;FGB common genes common pathways 15825:[DB04833 DB05679] DB04833|Methaqualone CYP3A4 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways 15826:[DB04833 DB13203] DB04833|Methaqualone CYP3A4 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 15827:[DB04833 DB06479] DB04833|Methaqualone CYP3A4 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 15828:[DB04833 DB08885] DB04833|Methaqualone CYP3A4 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways 15829:[DB04833 DB03832] DB04833|Methaqualone CYP3A4 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways GO:0006629| lipid metabolic process CROT;CYP3A4 15830:[DB04833 DB02353] DB04833|Methaqualone CYP3A4 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways 15831:[DB04833 DB11760] DB04833|Methaqualone CYP3A4 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes common pathways 15832:[DB04833 DB08750] DB04833|Methaqualone CYP3A4 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 15833:[DB04833 DB02691] DB04833|Methaqualone CYP3A4 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FABP6 15834:[DB04833 DB01399] DB04833|Methaqualone CYP3A4 DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 15835:[DB04833 DB05514] DB04833|Methaqualone CYP3A4 DB05514|Cobiprostone CLCN2 common genes common pathways 15836:[DB04833 DB07831] DB04833|Methaqualone CYP3A4 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways 15837:[DB04833 DB09091] DB04833|Methaqualone CYP3A4 DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways 15838:[DB04833 DB07396] DB04833|Methaqualone CYP3A4 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways 15839:[DB04833 DB05796] DB04833|Methaqualone CYP3A4 DB05796|Daglutril MME common genes common pathways 15840:[DB04833 DB00078] DB04833|Methaqualone CYP3A4 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 15841:[DB04833 DB09140] DB04833|Methaqualone CYP3A4 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0055114| oxidation-reduction process NOX1;MT-CO1;CYP3A4 15842:[DB04833 DB01237] DB04833|Methaqualone CYP3A4 DB01237|Bromodiphenhydramine HRH1;SLC22A6 common genes common pathways 15843:[DB04833 DB08259] DB04833|Methaqualone CYP3A4 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;EPHX2 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0017144| drug metabolic process CYP3A4;EPHX2 15844:[DB04833 DB01738] DB04833|Methaqualone CYP3A4 DB01738|Phosphorylcolamine PRKCB common genes common pathways 15845:[DB04833 DB06814] DB04833|Methaqualone CYP3A4 DB06814|Protokylol ADRB2 common genes common pathways 15846:[DB04833 DB07919] DB04833|Methaqualone CYP3A4 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 15847:[DB04833 DB03945] DB04833|Methaqualone CYP3A4 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways 15848:[DB04833 DB09064] DB04833|Methaqualone CYP3A4 DB09064|Ciprofibrate PPARA common genes common pathways GO:0006629| lipid metabolic process PPARA;CYP3A4 15849:[DB04833 DB03451] DB04833|Methaqualone CYP3A4 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways 15850:[DB04833 DB12118] DB04833|Methaqualone CYP3A4 DB12118|Sotatercept ACVR2A common genes common pathways 15851:[DB04833 DB02039] DB04833|Methaqualone CYP3A4 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways 15852:[DB04833 DB05234] DB04833|Methaqualone CYP3A4 DB05234|LGD2941 AR common genes common pathways 15853:[DB04833 DB04757] DB04833|Methaqualone CYP3A4 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways 15854:[DB04833 DB03435] DB04833|Methaqualone CYP3A4 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways 15855:[DB04833 DB08159] DB04833|Methaqualone CYP3A4 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways 15856:[DB04833 DB08101] DB04833|Methaqualone CYP3A4 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways 15857:[DB04833 DB00515] DB04833|Methaqualone CYP3A4 DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2B6;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2B6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process GSTP1;CYP2C9;NQO1;CYP2B6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2B6;CYP3A4 GO:0055114| oxidation-reduction process NQO1;CYP2C9;CYP2B6;CYP3A4;SOD1;CYP4A11;PTGS2;XDH;MPO 15858:[DB04833 DB12688] DB04833|Methaqualone CYP3A4 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways 15859:[DB04833 DB02282] DB04833|Methaqualone CYP3A4 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 15860:[DB04833 DB11869] DB04833|Methaqualone CYP3A4 DB11869|Valspodar SLCO1B1;SLCO1B3 common genes common pathways 15861:[DB04833 DB06039] DB04833|Methaqualone CYP3A4 DB06039|PA-1050040 gag common genes common pathways 15862:[DB04833 DB02311] DB04833|Methaqualone CYP3A4 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways 15863:[DB04833 DB04069] DB04833|Methaqualone CYP3A4 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways 15864:[DB04833 DB00178] DB04833|Methaqualone CYP3A4 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways 15865:[DB04833 DB00592] DB04833|Methaqualone CYP3A4 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 15866:[DB04833 DB01160] DB04833|Methaqualone CYP3A4 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways 15867:[DB04833 DB13996] DB04833|Methaqualone CYP3A4 DB13996|Magnesium acetate ATP1A1 common genes common pathways 15868:[DB04833 DB00815] DB04833|Methaqualone CYP3A4 DB00815|Sodium lauryl sulfate ALB common genes common pathways 15869:[DB04833 DB00839] DB04833|Methaqualone CYP3A4 DB00839|Tolazamide ABCC8;KCNJ11;CYP2C9 common genes common pathways GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 15870:[DB04833 DB03253] DB04833|Methaqualone CYP3A4 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways 15871:[DB04833 DB00925] DB04833|Methaqualone CYP3A4 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways 15872:[DB04833 DB12418] DB04833|Methaqualone CYP3A4 DB12418|Saccharin CA3 common genes common pathways 15873:[DB04833 DB07837] DB04833|Methaqualone CYP3A4 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways 15874:[DB04833 DB01811] DB04833|Methaqualone CYP3A4 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways 15875:[DB04833 DB00449] DB04833|Methaqualone CYP3A4 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways 15876:[DB04833 DB12061] DB04833|Methaqualone CYP3A4 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways 15877:[DB04833 DB06215] DB04833|Methaqualone CYP3A4 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0055114| oxidation-reduction process FTH1;CYP3A4 15878:[DB04833 DB01444] DB04833|Methaqualone CYP3A4 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes common pathways 15879:[DB04833 DB05417] DB04833|Methaqualone CYP3A4 DB05417|GW 468816 GLRA1 common genes common pathways 15880:[DB04833 DB02338] DB04833|Methaqualone CYP3A4 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0055114| oxidation-reduction process AASS;TXNRD1;DPYD;CYP3A4 15881:[DB04833 DB01973] DB04833|Methaqualone CYP3A4 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 15882:[DB04833 DB00373] DB04833|Methaqualone CYP3A4 DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 15883:[DB04833 DB09462] DB04833|Methaqualone CYP3A4 DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;ALDH1A1;ADH1B GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;GSTP1 GO:0006629| lipid metabolic process PLA2G2E;ISYNA1;HPGDS;CYP3A4;PPARD GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 15884:[DB04833 DB02508] DB04833|Methaqualone CYP3A4 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 15885:[DB04833 DB00319] DB04833|Methaqualone CYP3A4 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways 15886:[DB04833 DB09340] DB04833|Methaqualone CYP3A4 DB09340|Tyropanoic acid GUSB common genes common pathways 15887:[DB04833 DB00716] DB04833|Methaqualone CYP3A4 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways 15888:[DB04833 DB04685] DB04833|Methaqualone CYP3A4 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways 15889:[DB04833 DB00030] DB04833|Methaqualone CYP3A4 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0006629| lipid metabolic process LRP2;CYP3A4 GO:0042359| vitamin D metabolic process LRP2;CYP3A4 15890:[DB04833 DB00796] DB04833|Methaqualone CYP3A4 DB00796|Candesartan cilexetil AGTR1;CYP2C9;CYP2C8;UGT1A3;PTGS1;ABCB1 common genes common pathways GO:0002933| CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A3;CYP3A4;CYP2C8;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS1;CYP2C9;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;PTGS1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4;PTGS1 15891:[DB04833 DB13967] DB04833|Methaqualone CYP3A4 DB13967|Patent Blue ALB common genes common pathways 15892:[DB04833 DB07696] DB04833|Methaqualone CYP3A4 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways 15893:[DB04833 DB13884] DB04833|Methaqualone CYP3A4 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;F8 15894:[DB04833 DB00275] DB04833|Methaqualone CYP3A4 DB00275|Olmesartan AGTR1;ABCC2;SLCO1B3;SLCO1B1;ABCB11 common genes common pathways 15895:[DB04833 DB03650] DB04833|Methaqualone CYP3A4 DB03650|(3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One PIM1 common genes common pathways 15896:[DB04833 DB11995] DB04833|Methaqualone CYP3A4 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0002933| CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 15897:[DB04833 DB14600] DB04833|Methaqualone CYP3A4 DB14600|Edetate disodium anhydrous ADA;CYP1A2;PON3;CYP19A1 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 15898:[DB04833 DB06457] DB04833|Methaqualone CYP3A4 DB06457|Tecastemizole KCNH2 common genes common pathways 15899:[DB04833 DB05413] DB04833|Methaqualone CYP3A4 DB05413|Tifuvirtide SERPINA5 common genes common pathways 15900:[DB04833 DB07117] DB04833|Methaqualone CYP3A4 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 15901:[DB04833 DB06371] DB04833|Methaqualone CYP3A4 DB06371|Siplizumab CD2 common genes common pathways 15902:[DB04833 DB06602] DB04833|Methaqualone CYP3A4 DB06602|Reslizumab IL5 common genes common pathways 15903:[DB04833 DB04119] DB04833|Methaqualone CYP3A4 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways 15904:[DB04833 DB07930] DB04833|Methaqualone CYP3A4 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways GO:0006629| lipid metabolic process ACOX1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;ACOX1 15905:[DB04833 DB11949] DB04833|Methaqualone CYP3A4 DB11949|Vestipitant TACR1 common genes common pathways 15906:[DB04833 DB07500] DB04833|Methaqualone CYP3A4 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2E 15907:[DB04833 DB01704] DB04833|Methaqualone CYP3A4 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways 15908:[DB04833 DB12874] DB04833|Methaqualone CYP3A4 DB12874|Quizartinib FLT3 common genes common pathways 15909:[DB04833 DB05750] DB04833|Methaqualone CYP3A4 DB05750|AVE-1625 CNR1 common genes common pathways 15910:[DB04833 DB05394] DB04833|Methaqualone CYP3A4 DB05394|Corticorelin DBH common genes common pathways GO:0055114| oxidation-reduction process DBH;CYP3A4 15911:[DB04833 DB04115] DB04833|Methaqualone CYP3A4 DB04115|Berberine BIRC5 common genes common pathways 15912:[DB04833 DB02660] DB04833|Methaqualone CYP3A4 DB02660|Filaminast PDE4B common genes common pathways 15913:[DB04833 DB00465] DB04833|Methaqualone CYP3A4 DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 15914:[DB04833 DB00720] DB04833|Methaqualone CYP3A4 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 15915:[DB04833 DB01147] DB04833|Methaqualone CYP3A4 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 15916:[DB04833 DB02932] DB04833|Methaqualone CYP3A4 DB02932|(R)-Bicalutamide AR common genes common pathways 15917:[DB04833 DB00573] DB04833|Methaqualone CYP3A4 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4 GO:0006629| lipid metabolic process PPARG;PTGS1;PTGS2;PPARA;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 15918:[DB04833 DB00120] DB04833|Methaqualone CYP3A4 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process TH;CYP3A4;PAH 15919:[DB04833 DB07677] DB04833|Methaqualone CYP3A4 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 15920:[DB04833 DB09329] DB04833|Methaqualone CYP3A4 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways 15921:[DB04833 DB02758] DB04833|Methaqualone CYP3A4 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 15922:[DB04833 DB00788] DB04833|Methaqualone CYP3A4 DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process UGT2B7;PTGS1;CYP3A4;PTGS2;CYP1A2;CYP2C9 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP1A2;PTGS2;CYP3A4;PTGS1 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9;UGT2B7;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2C8 GO:0002933| CYP2C8;CYP3A4 15923:[DB04833 DB07509] DB04833|Methaqualone CYP3A4 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 15924:[DB04833 DB01647] DB04833|Methaqualone CYP3A4 DB01647|Daxalipram PDE4B common genes common pathways 15925:[DB04833 DB00869] DB04833|Methaqualone CYP3A4 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 15926:[DB04833 DB03849] DB04833|Methaqualone CYP3A4 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways 15927:[DB04833 DB07701] DB04833|Methaqualone CYP3A4 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways 15928:[DB04833 DB07561] DB04833|Methaqualone CYP3A4 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 15929:[DB04833 DB00147] DB04833|Methaqualone CYP3A4 DB00147|Pyridoxal PDXK common genes common pathways 15930:[DB04833 DB01541] DB04833|Methaqualone CYP3A4 DB01541|Boldenone AR common genes common pathways 15931:[DB04833 DB00133] DB04833|Methaqualone CYP3A4 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CBS GO:0006629| lipid metabolic process CYP3A4;SPTLC2;SPTLC1 15932:[DB04833 DB05422] DB04833|Methaqualone CYP3A4 DB05422|OPC-14523 SLC6A4 common genes common pathways 15933:[DB04833 DB13749] DB04833|Methaqualone CYP3A4 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways 15934:[DB04833 DB07173] DB04833|Methaqualone CYP3A4 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 15935:[DB04833 DB02890] DB04833|Methaqualone CYP3A4 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways 15936:[DB04833 DB00066] DB04833|Methaqualone CYP3A4 DB00066|Follitropin FSHR common genes common pathways 15937:[DB04833 DB08809] DB04833|Methaqualone CYP3A4 DB08809|Dichloroacetic Acid PDK1;GSTZ1 common genes common pathways 15938:[DB04833 DB11595] DB04833|Methaqualone CYP3A4 DB11595|Atezolizumab CD274 common genes common pathways 15939:[DB04833 DB01751] DB04833|Methaqualone CYP3A4 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways 15940:[DB04833 DB11135] DB04833|Methaqualone CYP3A4 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TXNRD1;GSR 15941:[DB04833 DB02774] DB04833|Methaqualone CYP3A4 DB02774|1,3-Propandiol ARF1 common genes common pathways 15942:[DB04833 DB04856] DB04833|Methaqualone CYP3A4 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP3A5 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9;CYP3A5 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP3A5;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0002933| CYP3A5;CYP3A4 GO:0036378| CYP3A4 15943:[DB04833 DB01582] DB04833|Methaqualone CYP3A4 DB01582|Sulfamethazine ALB common genes common pathways 15944:[DB04833 DB00397] DB04833|Methaqualone CYP3A4 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 15945:[DB04833 DB03944] DB04833|Methaqualone CYP3A4 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 15946:[DB04833 DB03413] DB04833|Methaqualone CYP3A4 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways 15947:[DB04833 DB04466] DB04833|Methaqualone CYP3A4 DB04466|SR12813 NR1I2 common genes common pathways GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2 GO:0008202| steroid metabolic process CYP3A4;NR1I2 15948:[DB04833 DB07629] DB04833|Methaqualone CYP3A4 DB07629|N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways 15949:[DB04833 DB02115] DB04833|Methaqualone CYP3A4 DB02115|Daidzin ALDH2;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP3A4 15950:[DB04833 DB09310] DB04833|Methaqualone CYP3A4 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 15951:[DB04833 DB05012] DB04833|Methaqualone CYP3A4 DB05012|XEN2174 SLC6A2 common genes common pathways 15952:[DB04833 DB02636] DB04833|Methaqualone CYP3A4 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 15953:[DB04833 DB04436] DB04833|Methaqualone CYP3A4 DB04436|3-Fluorotyrosine SOD2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD2 15954:[DB04833 DB13876] DB04833|Methaqualone CYP3A4 DB13876|Brofaromine MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 15955:[DB04833 DB09047] DB04833|Methaqualone CYP3A4 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways 15956:[DB04833 DB01666] DB04833|Methaqualone CYP3A4 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways 15957:[DB04833 DB04121] DB04833|Methaqualone CYP3A4 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways 15958:[DB04833 DB06249] DB04833|Methaqualone CYP3A4 DB06249|Arzoxifene ESR1;ESR2 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 15959:[DB04833 DB04941] DB04833|Methaqualone CYP3A4 DB04941|Crofelemer CFTR;ANO1 common genes common pathways 15960:[DB04833 DB06133] DB04833|Methaqualone CYP3A4 DB06133|Dimethylcurcumin AR common genes common pathways 15961:[DB04833 DB07193] DB04833|Methaqualone CYP3A4 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways 15962:[DB04833 DB07754] DB04833|Methaqualone CYP3A4 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways 15963:[DB04833 DB12379] DB04833|Methaqualone CYP3A4 DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0006805| xenobiotic metabolic process AHR;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0002933| CYP3A4;CYP1A1 15964:[DB04833 DB01576] DB04833|Methaqualone CYP3A4 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways 15965:[DB04833 DB03615] DB04833|Methaqualone CYP3A4 DB03615|Ribostamycin P4HB;rpsL common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;P4HB 15966:[DB04833 DB11560] DB04833|Methaqualone CYP3A4 DB11560|Lesinurad SLC22A12;SLC22A11;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 15967:[DB04833 DB13999] DB04833|Methaqualone CYP3A4 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0006629| lipid metabolic process LRP1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PHYH 15968:[DB04833 DB11598] DB04833|Methaqualone CYP3A4 DB11598|Antithrombin III human SERPINC1 common genes common pathways 15969:[DB04833 DB06205] DB04833|Methaqualone CYP3A4 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes common pathways 15970:[DB04833 DB11450] DB04833|Methaqualone CYP3A4 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 15971:[DB04833 DB01838] DB04833|Methaqualone CYP3A4 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways 15972:[DB04833 DB08020] DB04833|Methaqualone CYP3A4 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 15973:[DB04833 DB02236] DB04833|Methaqualone CYP3A4 DB02236|Glycinamide Ribonucleotide GART common genes common pathways 15974:[DB04833 DB01185] DB04833|Methaqualone CYP3A4 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process HSD11B2;CYP3A4 15975:[DB04833 DB00606] DB04833|Methaqualone CYP3A4 DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways 15976:[DB04833 DB01756] DB04833|Methaqualone CYP3A4 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 15977:[DB04833 DB08022] DB04833|Methaqualone CYP3A4 DB08022|(2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile PIM1 common genes common pathways 15978:[DB04833 DB07512] DB04833|Methaqualone CYP3A4 DB07512|7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOB;CYP3A4 15979:[DB04833 DB06926] DB04833|Methaqualone CYP3A4 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 15980:[DB04833 DB00999] DB04833|Methaqualone CYP3A4 DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways 15981:[DB04833 DB06691] DB04833|Methaqualone CYP3A4 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 15982:[DB04833 DB07318] DB04833|Methaqualone CYP3A4 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NOS2 15983:[DB04833 DB08087] DB04833|Methaqualone CYP3A4 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways 15984:[DB04833 DB00146] DB04833|Methaqualone CYP3A4 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;CYP27B1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP27B1;CYP24A1 GO:0036378| CYP27B1;CYP3A4 15985:[DB04833 DB06210] DB04833|Methaqualone CYP3A4 DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C8;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A3;UGT1A9;UGT1A1;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 15986:[DB04833 DB06421] DB04833|Methaqualone CYP3A4 DB06421|Declopramide TOP2A;TOP2B common genes common pathways 15987:[DB04833 DB13133] DB04833|Methaqualone CYP3A4 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0055114| oxidation-reduction process F8;CYP3A4 15988:[DB04833 DB07977] DB04833|Methaqualone CYP3A4 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 15989:[DB04833 DB00233] DB04833|Methaqualone CYP3A4 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4;PTGS2 GO:0055114| oxidation-reduction process ALOX5;MPO;PTGS2;CYP3A4 15990:[DB04833 DB03183] DB04833|Methaqualone CYP3A4 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 15991:[DB04833 DB11606] DB04833|Methaqualone CYP3A4 DB11606|Susoctocog alfa VWF common genes common pathways 15992:[DB04833 DB05155] DB04833|Methaqualone CYP3A4 DB05155|CR665 OPRK1 common genes common pathways 15993:[DB04833 DB09080] DB04833|Methaqualone CYP3A4 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 15994:[DB04833 DB00585] DB04833|Methaqualone CYP3A4 DB00585|Nizatidine HRH2;BCHE;ABCB1 common genes common pathways 15995:[DB04833 DB00561] DB04833|Methaqualone CYP3A4 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways 15996:[DB04833 DB02144] DB04833|Methaqualone CYP3A4 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PITPNA 15997:[DB04833 DB11455] DB04833|Methaqualone CYP3A4 DB11455|Robenacoxib PTGS2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 15998:[DB04833 DB12598] DB04833|Methaqualone CYP3A4 DB12598|Nafamostat F2;F10;F12;PRSS1;KLK1;ICAM1;SLC22A1;SLC22A2 common genes common pathways 15999:[DB04833 DB02955] DB04833|Methaqualone CYP3A4 DB02955|Ricinoleic Acid CNR1;CNR2;TRPV1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;TRPV1 16000:[DB04833 DB02553] DB04833|Methaqualone CYP3A4 DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways GO:0055114| oxidation-reduction process GSR;CYP3A4 16001:[DB04833 DB08529] DB04833|Methaqualone CYP3A4 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 16002:[DB04833 DB00613] DB04833|Methaqualone CYP3A4 DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2D6 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1B1;CYP2C8;CYP2D6;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP1B1;CYP2C8;CYP2D6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C8;CYP2C9;CYP1A1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP2C9;CYP3A4 GO:0002933| CYP3A4;CYP2C8;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 16003:[DB04833 DB01197] DB04833|Methaqualone CYP3A4 DB01197|Captopril ACE;MMP2;MMP9;LTA4H;BDKRB1;CYP2D6;ALB;ABCB1;SLC15A1;SLC22A6 common genes common pathways GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 16004:[DB04833 DB09266] DB04833|Methaqualone CYP3A4 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways 16005:[DB04833 DB02011] DB04833|Methaqualone CYP3A4 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways 16006:[DB04833 DB04709] DB04833|Methaqualone CYP3A4 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways 16007:[DB04833 DB01612] DB04833|Methaqualone CYP3A4 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP3A4 16008:[DB04833 DB01777] DB04833|Methaqualone CYP3A4 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways 16009:[DB04833 DB09220] DB04833|Methaqualone CYP3A4 DB09220|Nicorandil ABCC9 common genes common pathways 16010:[DB04833 DB14518] DB04833|Methaqualone CYP3A4 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways 16011:[DB04833 DB07684] DB04833|Methaqualone CYP3A4 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways 16012:[DB04833 DB07300] DB04833|Methaqualone CYP3A4 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways 16013:[DB04833 DB12733] DB04833|Methaqualone CYP3A4 DB12733|Dipraglurant GRM5 common genes common pathways 16014:[DB04833 DB02735] DB04833|Methaqualone CYP3A4 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways GO:0008202| steroid metabolic process CYP3A4;STS GO:0006706| steroid catabolic process CYP3A4;STS GO:0006629| lipid metabolic process STS;CYP3A4 16015:[DB04833 DB00867] DB04833|Methaqualone CYP3A4 DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PGD 16016:[DB04833 DB02507] DB04833|Methaqualone CYP3A4 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 16017:[DB04833 DB06150] DB04833|Methaqualone CYP3A4 DB06150|Sulfadimethoxine CYP2C9 common genes common pathways GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 16018:[DB04833 DB03169] DB04833|Methaqualone CYP3A4 DB03169|(S)-Hmg-Coa HMGCR common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP3A4 GO:0006629| lipid metabolic process HMGCR;CYP3A4 GO:0008202| steroid metabolic process HMGCR;CYP3A4 16019:[DB04833 DB01586] DB04833|Methaqualone CYP3A4 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;AKR1C2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process AKR1C2;CYP2E1;CYP3A4;ABCC4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;AKR1C2 16020:[DB04833 DB00880] DB04833|Methaqualone CYP3A4 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways 16021:[DB04833 DB05495] DB04833|Methaqualone CYP3A4 DB05495|PG-530742 MMP9 common genes common pathways 16022:[DB04833 DB11113] DB04833|Methaqualone CYP3A4 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways 16023:[DB04833 DB12339] DB04833|Methaqualone CYP3A4 DB12339|Radezolid RRBP1;NIP7 common genes common pathways 16024:[DB04833 DB11085] DB04833|Methaqualone CYP3A4 DB11085|Resorcinol TPO common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TPO 16025:[DB04833 DB13772] DB04833|Methaqualone CYP3A4 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 16026:[DB04833 DB03866] DB04833|Methaqualone CYP3A4 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 16027:[DB04833 DB03085] DB04833|Methaqualone CYP3A4 DB03085|Glycolic acid G6PD;thiO common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;G6PD GO:0006629| lipid metabolic process CYP3A4;G6PD 16028:[DB04833 DB12579] DB04833|Methaqualone CYP3A4 DB12579|JNJ-37822681 DRD2 common genes common pathways 16029:[DB04833 DB03773] DB04833|Methaqualone CYP3A4 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 16030:[DB04833 DB07460] DB04833|Methaqualone CYP3A4 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways 16031:[DB04833 DB05116] DB04833|Methaqualone CYP3A4 DB05116|Thymectacin TYMS common genes common pathways 16032:[DB04833 DB00411] DB04833|Methaqualone CYP3A4 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;CYP3A4 16033:[DB04833 DB04860] DB04833|Methaqualone CYP3A4 DB04860|Isatoribine TLR7 common genes common pathways 16034:[DB04833 DB00291] DB04833|Methaqualone CYP3A4 DB00291|Chlorambucil GSTP1;SLCO1A2 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP3A4 16035:[DB04833 DB00841] DB04833|Methaqualone CYP3A4 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 16036:[DB04833 DB08228] DB04833|Methaqualone CYP3A4 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process NQO2;CYP3A4 GO:0055114| oxidation-reduction process NQO2;CYP3A4 16037:[DB04833 DB05046] DB04833|Methaqualone CYP3A4 DB05046|V1003 OPRK1;OPRM1 common genes common pathways 16038:[DB04833 DB06901] DB04833|Methaqualone CYP3A4 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 16039:[DB04833 DB07691] DB04833|Methaqualone CYP3A4 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARD 16040:[DB04833 DB01214] DB04833|Methaqualone CYP3A4 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 16041:[DB04833 DB00044] DB04833|Methaqualone CYP3A4 DB00044|Lutropin alfa LHCGR common genes common pathways 16042:[DB04833 DB08808] DB04833|Methaqualone CYP3A4 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 16043:[DB04833 DB07693] DB04833|Methaqualone CYP3A4 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways 16044:[DB04833 DB14059] DB04833|Methaqualone CYP3A4 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 16045:[DB04833 DB06064] DB04833|Methaqualone CYP3A4 DB06064|KAI-1455 PRKCE common genes common pathways 16046:[DB04833 DB07517] DB04833|Methaqualone CYP3A4 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways 16047:[DB04833 DB08157] DB04833|Methaqualone CYP3A4 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways 16048:[DB04833 DB01309] DB04833|Methaqualone CYP3A4 DB01309|Insulin Glulisine INSR common genes common pathways 16049:[DB04833 DB00040] DB04833|Methaqualone CYP3A4 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 16050:[DB04833 DB11087] DB04833|Methaqualone CYP3A4 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0008202| steroid metabolic process NR1I2;CYP3A4 GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4 GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4 16051:[DB04833 DB06736] DB04833|Methaqualone CYP3A4 DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PTGS1;PTGS2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;PTGS1;CYP3A4;PTGS2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 16052:[DB04833 DB11988] DB04833|Methaqualone CYP3A4 DB11988|Ocrelizumab MS4A1 common genes common pathways 16053:[DB04833 DB01700] DB04833|Methaqualone CYP3A4 DB01700|AICA ribonucleotide ATIC common genes common pathways 16054:[DB04833 DB05455] DB04833|Methaqualone CYP3A4 DB05455|SR 121463 AVPR1B common genes common pathways 16055:[DB04833 DB14034] DB04833|Methaqualone CYP3A4 DB14034|Darglitazone PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 16056:[DB04833 DB07559] DB04833|Methaqualone CYP3A4 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 16057:[DB04833 DB00640] DB04833|Methaqualone CYP3A4 DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways 16058:[DB04833 DB04429] DB04833|Methaqualone CYP3A4 DB04429|4'-Hydroxyflavanone SHBG common genes common pathways 16059:[DB04833 DB05018] DB04833|Methaqualone CYP3A4 DB05018|Migalastat GLA;UGT1A1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 16060:[DB04833 DB08692] DB04833|Methaqualone CYP3A4 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 16061:[DB04833 DB04881] DB04833|Methaqualone CYP3A4 DB04881|Elacridar ABCB1;ABCG2;SLCO1B1 common genes common pathways 16062:[DB04833 DB03962] DB04833|Methaqualone CYP3A4 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways GO:0055114| oxidation-reduction process PGD;CYP3A4 16063:[DB04833 DB08736] DB04833|Methaqualone CYP3A4 DB08736|S,R-Warfarin alcohol ALB common genes common pathways 16064:[DB04833 DB00695] DB04833|Methaqualone CYP3A4 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0055114| oxidation-reduction process PGD;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 16065:[DB04833 DB09129] DB04833|Methaqualone CYP3A4 DB09129|Chromic chloride INSR common genes common pathways 16066:[DB04833 DB06796] DB04833|Methaqualone CYP3A4 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD2 16067:[DB04833 DB06533] DB04833|Methaqualone CYP3A4 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARA;PPARG 16068:[DB04833 DB06472] DB04833|Methaqualone CYP3A4 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways 16069:[DB04833 DB07247] DB04833|Methaqualone CYP3A4 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways 16070:[DB04833 DB07140] DB04833|Methaqualone CYP3A4 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 16071:[DB04833 DB00384] DB04833|Methaqualone CYP3A4 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 16072:[DB04833 DB05916] DB04833|Methaqualone CYP3A4 DB05916|CT-011 PDCD1 common genes common pathways 16073:[DB04833 DB07814] DB04833|Methaqualone CYP3A4 DB07814|Gibberellic acid AADACL2 common genes common pathways 16074:[DB04833 DB01902] DB04833|Methaqualone CYP3A4 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways GO:0055114| oxidation-reduction process ERO1B;CYP3A4 16075:[DB04833 DB02568] DB04833|Methaqualone CYP3A4 DB02568|Peldesine PNP common genes common pathways 16076:[DB04833 DB06750] DB04833|Methaqualone CYP3A4 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways 16077:[DB04833 DB00743] DB04833|Methaqualone CYP3A4 DB00743|Gadobenic acid ALB common genes common pathways 16078:[DB04833 DB03609] DB04833|Methaqualone CYP3A4 DB03609|3-Deoxyguanosine PNP common genes common pathways 16079:[DB04833 DB13949] DB04833|Methaqualone CYP3A4 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways 16080:[DB04833 DB01092] DB04833|Methaqualone CYP3A4 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A1 GO:0002933| CYP3A4;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 16081:[DB04833 DB01428] DB04833|Methaqualone CYP3A4 DB01428|Oxybenzone PGR;AR;ESR1;ESR2 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 16082:[DB04833 DB01077] DB04833|Methaqualone CYP3A4 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 16083:[DB04833 DB03255] DB04833|Methaqualone CYP3A4 DB03255|Phenol cobT;ALB common genes common pathways 16084:[DB04833 DB07437] DB04833|Methaqualone CYP3A4 DB07437|1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE UPP1 common genes common pathways 16085:[DB04833 DB05125] DB04833|Methaqualone CYP3A4 DB05125|SC12267 DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 16086:[DB04833 DB05487] DB04833|Methaqualone CYP3A4 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 16087:[DB04833 DB00942] DB04833|Methaqualone CYP3A4 DB00942|Cycrimine CHRM1 common genes common pathways 16088:[DB04833 DB02761] DB04833|Methaqualone CYP3A4 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways 16089:[DB04833 DB08860] DB04833|Methaqualone CYP3A4 DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A3;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;HMGCR;CYP2C8;CYP2C9 GO:0002933| CYP2C8;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process HMGCR;CYP3A4;UGT2B7;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4;HMGCR 16090:[DB04833 DB08077] DB04833|Methaqualone CYP3A4 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways 16091:[DB04833 DB14533] DB04833|Methaqualone CYP3A4 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0008202| steroid metabolic process APOBR;APOA1;APOE;CYP3A4;APOL1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process PRDX1;PDIA3;GAPDHS;CP;CCS;ADH1C;P4HB;CYP3A4;SOD1 GO:0006629| lipid metabolic process APOL1;PON1;C3;CYP3A4;APOE;CLU;APOBR;APOA1 16092:[DB04833 DB06837] DB04833|Methaqualone CYP3A4 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways 16093:[DB04833 DB07962] DB04833|Methaqualone CYP3A4 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways 16094:[DB04833 DB03861] DB04833|Methaqualone CYP3A4 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways 16095:[DB04833 DB07714] DB04833|Methaqualone CYP3A4 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GSR 16096:[DB04833 DB01966] DB04833|Methaqualone CYP3A4 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways GO:0006629| lipid metabolic process PSAP;CYP3A4 16097:[DB04833 DB04816] DB04833|Methaqualone CYP3A4 DB04816|Dantron ALB common genes common pathways 16098:[DB04833 DB05076] DB04833|Methaqualone CYP3A4 DB05076|Fenretinide RBP4 common genes common pathways 16099:[DB04833 DB04846] DB04833|Methaqualone CYP3A4 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 16100:[DB04833 DB08660] DB04833|Methaqualone CYP3A4 DB08660|1,2,5,8-tetrahydroxyanthracene-9,10-dione CSNK2A1 common genes common pathways 16101:[DB04833 DB05713] DB04833|Methaqualone CYP3A4 DB05713|LY-517717 F10 common genes common pathways 16102:[DB04833 DB00992] DB04833|Methaqualone CYP3A4 DB00992|Methyl aminolevulinate FCGR1A common genes common pathways 16103:[DB04833 DB03994] DB04833|Methaqualone CYP3A4 DB03994|Ethanolamine ANXA3 common genes common pathways 16104:[DB04833 DB04400] DB04833|Methaqualone CYP3A4 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0055114| oxidation-reduction process PAH;NOS2;CYP3A4;TH;PCBD1 16105:[DB04833 DB01791] DB04833|Methaqualone CYP3A4 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways 16106:[DB04833 DB00896] DB04833|Methaqualone CYP3A4 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 16107:[DB04833 DB04594] DB04833|Methaqualone CYP3A4 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HMGCL 16108:[DB04833 DB03645] DB04833|Methaqualone CYP3A4 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways 16109:[DB04833 DB11827] DB04833|Methaqualone CYP3A4 DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;UGT2B7;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A9;UGT1A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;UGT2B7 GO:0006805| xenobiotic metabolic process CYP3A4;UGT1A9 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 16110:[DB04833 DB02581] DB04833|Methaqualone CYP3A4 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways 16111:[DB04833 DB06599] DB04833|Methaqualone CYP3A4 DB06599|Lexatumumab TNFRSF10B common genes common pathways 16112:[DB04833 DB05471] DB04833|Methaqualone CYP3A4 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways 16113:[DB04833 DB06870] DB04833|Methaqualone CYP3A4 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways 16114:[DB04833 DB07395] DB04833|Methaqualone CYP3A4 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways 16115:[DB04833 DB08119] DB04833|Methaqualone CYP3A4 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 16116:[DB04833 DB07072] DB04833|Methaqualone CYP3A4 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways 16117:[DB04833 DB06705] DB04833|Methaqualone CYP3A4 DB06705|Gadofosveset trisodium ALB common genes common pathways 16118:[DB04833 DB08934] DB04833|Methaqualone CYP3A4 DB08934|Sofosbuvir CTSA;HINT1;CMPK1;NME1;ABCB1;ABCG2 common genes common pathways 16119:[DB04833 DB01640] DB04833|Methaqualone CYP3A4 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways 16120:[DB04833 DB05708] DB04833|Methaqualone CYP3A4 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 16121:[DB04833 DB08843] DB04833|Methaqualone CYP3A4 DB08843|GS 0573 SLC22A6 common genes common pathways 16122:[DB04833 DB00383] DB04833|Methaqualone CYP3A4 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways 16123:[DB04833 DB07613] DB04833|Methaqualone CYP3A4 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 16124:[DB04833 DB07261] DB04833|Methaqualone CYP3A4 DB07261|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE F10 common genes common pathways 16125:[DB04833 DB06849] DB04833|Methaqualone CYP3A4 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways 16126:[DB04833 DB00616] DB04833|Methaqualone CYP3A4 DB00616|Candoxatril MME;ACE common genes common pathways 16127:[DB04833 DB06147] DB04833|Methaqualone CYP3A4 DB06147|Sulfathiazole CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 16128:[DB04833 DB01662] DB04833|Methaqualone CYP3A4 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways 16129:[DB04833 DB07350] DB04833|Methaqualone CYP3A4 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways 16130:[DB04833 DB07849] DB04833|Methaqualone CYP3A4 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP3A4 16131:[DB04833 DB11855] DB04833|Methaqualone CYP3A4 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 16132:[DB04833 DB00264] DB04833|Methaqualone CYP3A4 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C19 16133:[DB04833 DB07007] DB04833|Methaqualone CYP3A4 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 16134:[DB04833 DB09536] DB04833|Methaqualone CYP3A4 DB09536|Titanium dioxide MARCO common genes common pathways 16135:[DB04833 DB05253] DB04833|Methaqualone CYP3A4 DB05253|Proellex PGR common genes common pathways 16136:[DB04833 DB04418] DB04833|Methaqualone CYP3A4 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways 16137:[DB04833 DB00523] DB04833|Methaqualone CYP3A4 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP26C1;CYP3A4 16138:[DB04833 DB00259] DB04833|Methaqualone CYP3A4 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 16139:[DB04833 DB00288] DB04833|Methaqualone CYP3A4 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 16140:[DB04833 DB00156] DB04833|Methaqualone CYP3A4 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways 16141:[DB04833 DB13503] DB04833|Methaqualone CYP3A4 DB13503|Tyrothricin ACHE common genes common pathways 16142:[DB04833 DB09279] DB04833|Methaqualone CYP3A4 DB09279|Fimasartan AGTR1 common genes common pathways 16143:[DB04833 DB03124] DB04833|Methaqualone CYP3A4 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways 16144:[DB04833 DB08626] DB04833|Methaqualone CYP3A4 DB08626|Thiorphan MME common genes common pathways 16145:[DB04833 DB05115] DB04833|Methaqualone CYP3A4 DB05115|NN344 INSR common genes common pathways 16146:[DB04833 DB08345] DB04833|Methaqualone CYP3A4 DB08345|4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 16147:[DB04833 DB06042] DB04833|Methaqualone CYP3A4 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways 16148:[DB04833 DB01832] DB04833|Methaqualone CYP3A4 DB01832|4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid FAH common genes common pathways 16149:[DB04833 DB03425] DB04833|Methaqualone CYP3A4 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways 16150:[DB04833 DB08060] DB04833|Methaqualone CYP3A4 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways 16151:[DB04833 DB05264] DB04833|Methaqualone CYP3A4 DB05264|NPI 32101 CSF2RB common genes common pathways 16152:[DB04833 DB01742] DB04833|Methaqualone CYP3A4 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways 16153:[DB04833 DB00750] DB04833|Methaqualone CYP3A4 DB00750|Prilocaine SCN5A common genes common pathways 16154:[DB04833 DB05849] DB04833|Methaqualone CYP3A4 DB05849|NCX 950 ADRB2 common genes common pathways 16155:[DB04833 DB03470] DB04833|Methaqualone CYP3A4 DB03470|Trypanothione TPR common genes common pathways 16156:[DB04833 DB04445] DB04833|Methaqualone CYP3A4 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SULT2A1 GO:0008202| steroid metabolic process CYP3A4;SULT2A1 16157:[DB04833 DB04133] DB04833|Methaqualone CYP3A4 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 16158:[DB04833 DB04934] DB04833|Methaqualone CYP3A4 DB04934|Rifalazil rpoB;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 16159:[DB04833 DB00751] DB04833|Methaqualone CYP3A4 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes CYP3A4 common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2B6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;CYP2D6 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2B6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6;CYP2B6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 16160:[DB04833 DB01537] DB04833|Methaqualone CYP3A4 DB01537|4-Bromo-2,5-dimethoxyphenethylamine HTR2C;HTR2A common genes common pathways 16161:[DB04833 DB00621] DB04833|Methaqualone CYP3A4 DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 16162:[DB04833 DB08972] DB04833|Methaqualone CYP3A4 DB08972|Flumequine CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 16163:[DB04833 DB05824] DB04833|Methaqualone CYP3A4 DB05824|CNS-5161 GRIN1 common genes common pathways 16164:[DB04833 DB01109] DB04833|Methaqualone CYP3A4 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways 16165:[DB04833 DB03988] DB04833|Methaqualone CYP3A4 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways 16166:[DB04833 DB11793] DB04833|Methaqualone CYP3A4 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways 16167:[DB04833 DB03316] DB04833|Methaqualone CYP3A4 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways 16168:[DB04833 DB06185] DB04833|Methaqualone CYP3A4 DB06185|Forodesine PNP common genes common pathways 16169:[DB04833 DB00374] DB04833|Methaqualone CYP3A4 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PPARD;CYP3A4 16170:[DB04833 DB08445] DB04833|Methaqualone CYP3A4 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways 16171:[DB04833 DB05875] DB04833|Methaqualone CYP3A4 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 16172:[DB04833 DB00958] DB04833|Methaqualone CYP3A4 DB00958|Carboplatin XDH;MPO;GSTT1;MT1A;MT2A;SOD1;GSTP1;GSTM1;NQO1;SLC31A1;SLC31A2;ATP7A;ATP7B;ABCG2;ABCC2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;NQO1;GSTP1 GO:0055114| oxidation-reduction process XDH;CYP3A4;SOD1;MPO;NQO1 16173:[DB04833 DB04880] DB04833|Methaqualone CYP3A4 DB04880|Enoximone PDE3A common genes common pathways GO:0006629| lipid metabolic process PDE3A;CYP3A4 16174:[DB04833 DB12007] DB04833|Methaqualone CYP3A4 DB12007|Isoflavone PPARA;PPARG common genes common pathways GO:0006629| lipid metabolic process PPARA;CYP3A4;PPARG 16175:[DB04833 DB08801] DB04833|Methaqualone CYP3A4 DB08801|Dimetindene HRH1;CHRM2 common genes common pathways 16176:[DB04833 DB06932] DB04833|Methaqualone CYP3A4 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways 16177:[DB04833 DB01762] DB04833|Methaqualone CYP3A4 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1 16178:[DB04833 DB02089] DB04833|Methaqualone CYP3A4 DB02089|CP-526423 PYGL common genes common pathways 16179:[DB04833 DB00527] DB04833|Methaqualone CYP3A4 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways 16180:[DB04833 DB00253] DB04833|Methaqualone CYP3A4 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 16181:[DB04833 DB05386] DB04833|Methaqualone CYP3A4 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways 16182:[DB04833 DB05429] DB04833|Methaqualone CYP3A4 DB05429|CAT-213 CCL11 common genes common pathways 16183:[DB04833 DB06127] DB04833|Methaqualone CYP3A4 DB06127|Bisegliptin DPP4 common genes common pathways 16184:[DB04833 DB07574] DB04833|Methaqualone CYP3A4 DB07574|2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE STMN4;TUBB2B;TUBA1A;TUBA1C;TUBA1B common genes common pathways 16185:[DB04833 DB09051] DB04833|Methaqualone CYP3A4 DB09051|Elosulfase alfa GALNS common genes common pathways 16186:[DB04833 DB06781] DB04833|Methaqualone CYP3A4 DB06781|Difluprednate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 16187:[DB04833 DB00939] DB04833|Methaqualone CYP3A4 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;CYP3A4;PTGS2 16188:[DB04833 DB02800] DB04833|Methaqualone CYP3A4 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways 16189:[DB04833 DB04931] DB04833|Methaqualone CYP3A4 DB04931|Afamelanotide MC1R common genes common pathways 16190:[DB04833 DB09151] DB04833|Methaqualone CYP3A4 DB09151|Flutemetamol (18F) APP common genes common pathways 16191:[DB04833 DB05945] DB04833|Methaqualone CYP3A4 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways 16192:[DB04833 DB07815] DB04833|Methaqualone CYP3A4 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways 16193:[DB04833 DB03478] DB04833|Methaqualone CYP3A4 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways 16194:[DB04833 DB01481] DB04833|Methaqualone CYP3A4 DB01481|1-Testosterone AR common genes common pathways 16195:[DB04833 DB01892] DB04833|Methaqualone CYP3A4 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0006805| xenobiotic metabolic process NR1I2;PTGS1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;CYP3A4 GO:0008202| steroid metabolic process NR1I2;CYP3A4 16196:[DB04833 DB06823] DB04833|Methaqualone CYP3A4 DB06823|Tiopronin MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;CYP3A4 16197:[DB04833 DB00369] DB04833|Methaqualone CYP3A4 DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways 16198:[DB04833 DB01141] DB04833|Methaqualone CYP3A4 DB01141|Micafungin COMT;ARSA common genes common pathways 16199:[DB04833 DB06804] DB04833|Methaqualone CYP3A4 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 16200:[DB04833 DB00826] DB04833|Methaqualone CYP3A4 DB00826|Natamycin CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 16201:[DB04833 DB07182] DB04833|Methaqualone CYP3A4 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 16202:[DB04833 DB02008] DB04833|Methaqualone CYP3A4 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0006629| lipid metabolic process PCK1;CYP3A4 16203:[DB04833 DB06754] DB04833|Methaqualone CYP3A4 DB06754|Danaparoid SERPINC1 common genes common pathways 16204:[DB04833 DB13346] DB04833|Methaqualone CYP3A4 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 16205:[DB04833 DB03546] DB04833|Methaqualone CYP3A4 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 16206:[DB04833 DB00325] DB04833|Methaqualone CYP3A4 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0002933| CYP3A4;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A1 16207:[DB04833 DB00287] DB04833|Methaqualone CYP3A4 DB00287|Travoprost PTGFR common genes common pathways 16208:[DB04833 DB01378] DB04833|Methaqualone CYP3A4 DB01378|Magnesium cation ATP1A1 common genes common pathways 16209:[DB04833 DB13931] DB04833|Methaqualone CYP3A4 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways 16210:[DB04833 DB04837] DB04833|Methaqualone CYP3A4 DB04837|Clofedanol HRH1 common genes common pathways 16211:[DB04833 DB05161] DB04833|Methaqualone CYP3A4 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;CYP3A4 16212:[DB04833 DB00179] DB04833|Methaqualone CYP3A4 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2J2 GO:0055114| oxidation-reduction process CYP3A4;CYP2J2;ALOX5 16213:[DB04833 DB08950] DB04833|Methaqualone CYP3A4 DB08950|Indoramin ADRA1A common genes common pathways 16214:[DB04833 DB07879] DB04833|Methaqualone CYP3A4 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways 16215:[DB04833 DB07453] DB04833|Methaqualone CYP3A4 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 16216:[DB04833 DB02179] DB04833|Methaqualone CYP3A4 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways 16217:[DB04833 DB03747] DB04833|Methaqualone CYP3A4 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways 16218:[DB04833 DB06819] DB04833|Methaqualone CYP3A4 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 16219:[DB04833 DB07668] DB04833|Methaqualone CYP3A4 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways 16220:[DB04833 DB07383] DB04833|Methaqualone CYP3A4 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways 16221:[DB04833 DB05304] DB04833|Methaqualone CYP3A4 DB05304|WX-G250 CA9;IL2 common genes common pathways 16222:[DB04833 DB00419] DB04833|Methaqualone CYP3A4 DB00419|Miglustat UGCG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;UGCG 16223:[DB04833 DB14528] DB04833|Methaqualone CYP3A4 DB14528|Chromium gluconate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYB5A;CYP3A4 16224:[DB04833 DB01763] DB04833|Methaqualone CYP3A4 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NNT 16225:[DB04833 DB00155] DB04833|Methaqualone CYP3A4 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;NOS1 GO:0055114| oxidation-reduction process CYP3A4;NOS3;NOS1;NOS2 16226:[DB04833 DB08813] DB04833|Methaqualone CYP3A4 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways 16227:[DB04833 DB01091] DB04833|Methaqualone CYP3A4 DB01091|Butenafine SQLE common genes common pathways GO:0055114| oxidation-reduction process SQLE;CYP3A4 16228:[DB04833 DB07003] DB04833|Methaqualone CYP3A4 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 16229:[DB04833 DB00055] DB04833|Methaqualone CYP3A4 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CP;F8 16230:[DB04833 DB12340] DB04833|Methaqualone CYP3A4 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways 16231:[DB04833 DB04606] DB04833|Methaqualone CYP3A4 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways 16232:[DB04833 DB00524] DB04833|Methaqualone CYP3A4 DB00524|Metolazone SLC12A3 common genes common pathways 16233:[DB04833 DB04890] DB04833|Methaqualone CYP3A4 DB04890|Bepotastine HRH1 common genes common pathways 16234:[DB04833 DB07992] DB04833|Methaqualone CYP3A4 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways 16235:[DB04833 DB03101] DB04833|Methaqualone CYP3A4 DB03101|Ribose-1-Phosphate PNP common genes common pathways 16236:[DB04833 DB08055] DB04833|Methaqualone CYP3A4 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways 16237:[DB04833 DB01776] DB04833|Methaqualone CYP3A4 DB01776|M-Cresol INS common genes common pathways 16238:[DB04833 DB09087] DB04833|Methaqualone CYP3A4 DB09087|Potassium alum ALB common genes common pathways 16239:[DB04833 DB09121] DB04833|Methaqualone CYP3A4 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways 16240:[DB04833 DB07342] DB04833|Methaqualone CYP3A4 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP3A4 16241:[DB04833 DB04377] DB04833|Methaqualone CYP3A4 DB04377|Meglutol HMGCR common genes common pathways GO:0006629| lipid metabolic process HMGCR;CYP3A4 GO:0055114| oxidation-reduction process HMGCR;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;HMGCR 16242:[DB04833 DB08206] DB04833|Methaqualone CYP3A4 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways 16243:[DB04833 DB02147] DB04833|Methaqualone CYP3A4 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways GO:0006629| lipid metabolic process C3;CYP3A4 16244:[DB04833 DB04106] DB04833|Methaqualone CYP3A4 DB04106|Fotemustine TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TXNRD1 16245:[DB04833 DB00032] DB04833|Methaqualone CYP3A4 DB00032|Menotropins FSHR;LHCGR common genes common pathways 16246:[DB04833 DB11652] DB04833|Methaqualone CYP3A4 DB11652|Tucatinib ERBB2 common genes common pathways 16247:[DB04833 DB08615] DB04833|Methaqualone CYP3A4 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways 16248:[DB04833 DB13158] DB04833|Methaqualone CYP3A4 DB13158|Clobetasone NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 16249:[DB04833 DB04112] DB04833|Methaqualone CYP3A4 DB04112|1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 16250:[DB04833 DB02097] DB04833|Methaqualone CYP3A4 DB02097|Cytidine UCK2 common genes common pathways 16251:[DB04833 DB14042] DB04833|Methaqualone CYP3A4 DB14042|Galcanezumab CALCA;CALCB common genes common pathways 16252:[DB04833 DB05416] DB04833|Methaqualone CYP3A4 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARA;PPARD 16253:[DB04833 DB05993] DB04833|Methaqualone CYP3A4 DB05993|PRX-07034 HTR6 common genes common pathways 16254:[DB04833 DB13914] DB04833|Methaqualone CYP3A4 DB13914|Volixibat SLC10A2 common genes common pathways 16255:[DB04833 DB03317] DB04833|Methaqualone CYP3A4 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYCS;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 16256:[DB04833 DB04027] DB04833|Methaqualone CYP3A4 DB04027|D-Arginine CKM common genes common pathways 16257:[DB04833 DB06433] DB04833|Methaqualone CYP3A4 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;RRM1 16258:[DB04833 DB04516] DB04833|Methaqualone CYP3A4 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ISYNA1 16259:[DB04833 DB00548] DB04833|Methaqualone CYP3A4 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0008202| steroid metabolic process AKR1D1;SRD5A2;CYP3A4 GO:0008209| androgen metabolic process SRD5A2;CYP3A4;AKR1D1 GO:0055114| oxidation-reduction process TYR;CYP3A4;SRD5A2;AKR1D1 GO:0006706| steroid catabolic process CYP3A4;SRD5A2 GO:0006629| lipid metabolic process SRD5A2;CYP3A4;AKR1D1 16260:[DB04833 DB06727] DB04833|Methaqualone CYP3A4 DB06727|Sparteine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 16261:[DB04833 DB00406] DB04833|Methaqualone CYP3A4 DB00406|Gentian violet cation SLC22A1 common genes common pathways 16262:[DB04833 DB09401] DB04833|Methaqualone CYP3A4 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways 16263:[DB04833 DB05309] DB04833|Methaqualone CYP3A4 DB05309|TP-508 FGF4 common genes common pathways 16264:[DB04833 DB03621] DB04833|Methaqualone CYP3A4 DB03621|L-709,587 FKBP1A common genes common pathways 16265:[DB04833 DB12212] DB04833|Methaqualone CYP3A4 DB12212|Landiolol CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 16266:[DB04833 DB05050] DB04833|Methaqualone CYP3A4 DB05050|ADL5859 OPRD1 common genes common pathways 16267:[DB04833 DB00929] DB04833|Methaqualone CYP3A4 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways 16268:[DB04833 DB01270] DB04833|Methaqualone CYP3A4 DB01270|Ranibizumab VEGFA common genes common pathways 16269:[DB04833 DB00799] DB04833|Methaqualone CYP3A4 DB00799|Tazarotene RARA;RXRB;RARG;RARB;CYP2C8 common genes common pathways GO:0002933| CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 16270:[DB04833 DB01581] DB04833|Methaqualone CYP3A4 DB01581|Sulfamerazine ALB common genes common pathways 16271:[DB04833 DB07246] DB04833|Methaqualone CYP3A4 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 16272:[DB04833 DB09033] DB04833|Methaqualone CYP3A4 DB09033|Vedolizumab ITGA4;ITGB7 common genes common pathways 16273:[DB04833 DB01000] DB04833|Methaqualone CYP3A4 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 16274:[DB04833 DB06154] DB04833|Methaqualone CYP3A4 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP3A4;NOS3 16275:[DB04833 DB00847] DB04833|Methaqualone CYP3A4 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MPO 16276:[DB04833 DB07029] DB04833|Methaqualone CYP3A4 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 16277:[DB04833 DB06939] DB04833|Methaqualone CYP3A4 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways 16278:[DB04833 DB06162] DB04833|Methaqualone CYP3A4 DB06162|Lumiliximab FCER2 common genes common pathways 16279:[DB04833 DB04270] DB04833|Methaqualone CYP3A4 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 16280:[DB04833 DB08186] DB04833|Methaqualone CYP3A4 DB08186|(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE KAT2B common genes common pathways 16281:[DB04833 DB06097] DB04833|Methaqualone CYP3A4 DB06097|GSK-923295 CENPE common genes common pathways 16282:[DB04833 DB09459] DB04833|Methaqualone CYP3A4 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways GO:0055114| oxidation-reduction process HIF1AN;CYP3A4 16283:[DB04833 DB08916] DB04833|Methaqualone CYP3A4 DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways 16284:[DB04833 DB05787] DB04833|Methaqualone CYP3A4 DB05787|LM-609 ITGB3 common genes common pathways 16285:[DB04833 DB08884] DB04833|Methaqualone CYP3A4 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ABCC4 16286:[DB04833 DB12712] DB04833|Methaqualone CYP3A4 DB12712|Pilsicainide ABCB11 common genes common pathways 16287:[DB04833 DB12961] DB04833|Methaqualone CYP3A4 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARA 16288:[DB04833 DB05458] DB04833|Methaqualone CYP3A4 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways 16289:[DB04833 DB06778] DB04833|Methaqualone CYP3A4 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes common pathways GO:0055114| oxidation-reduction process PAH;MT-CO1;MAOB;SOD1;CYP3A4;MAOA;LOX;TYR;CP 16290:[DB04833 DB01038] DB04833|Methaqualone CYP3A4 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways 16291:[DB04833 DB09028] DB04833|Methaqualone CYP3A4 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways 16292:[DB04833 DB08234] DB04833|Methaqualone CYP3A4 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 16293:[DB04833 DB05777] DB04833|Methaqualone CYP3A4 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways 16294:[DB04833 DB00452] DB04833|Methaqualone CYP3A4 DB00452|Framycetin rpsL;CXCR4 common genes common pathways 16295:[DB04833 DB03351] DB04833|Methaqualone CYP3A4 DB03351|Sri-9439 DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 16296:[DB04833 DB00937] DB04833|Methaqualone CYP3A4 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways 16297:[DB04833 DB13191] DB04833|Methaqualone CYP3A4 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways 16298:[DB04833 DB09067] DB04833|Methaqualone CYP3A4 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways 16299:[DB04833 DB08605] DB04833|Methaqualone CYP3A4 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways GO:0006629| lipid metabolic process DECR1;CYP3A4 GO:0055114| oxidation-reduction process DECR1;CYP3A4 16300:[DB04833 DB05934] DB04833|Methaqualone CYP3A4 DB05934|CTCE-0214 CXCL12 common genes common pathways 16301:[DB04833 DB06186] DB04833|Methaqualone CYP3A4 DB06186|Ipilimumab CTLA4 common genes common pathways 16302:[DB04833 DB06408] DB04833|Methaqualone CYP3A4 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0055114| oxidation-reduction process IMPDH1;CYP3A4 GO:0017144| drug metabolic process NT5C2;CYP3A4 16303:[DB04833 DB05260] DB04833|Methaqualone CYP3A4 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;RRM2 16304:[DB04833 DB04977] DB04833|Methaqualone CYP3A4 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2A6 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2E1;CYP4A11 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6 16305:[DB04833 DB01520] DB04833|Methaqualone CYP3A4 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways 16306:[DB04833 DB00724] DB04833|Methaqualone CYP3A4 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 16307:[DB04833 DB06271] DB04833|Methaqualone CYP3A4 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 16308:[DB04833 DB03467] DB04833|Methaqualone CYP3A4 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;AKR1C1;CYP19A1;CYP1B1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A4;AKR1C1 GO:0008202| steroid metabolic process CYP1B1;CYP3A4 16309:[DB04833 DB02230] DB04833|Methaqualone CYP3A4 DB02230|Immucillin-G PNP common genes common pathways 16310:[DB04833 DB00364] DB04833|Methaqualone CYP3A4 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways 16311:[DB04833 DB07756] DB04833|Methaqualone CYP3A4 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways 16312:[DB04833 DB08612] DB04833|Methaqualone CYP3A4 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 16313:[DB04833 DB07142] DB04833|Methaqualone CYP3A4 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 16314:[DB04833 DB08360] DB04833|Methaqualone CYP3A4 DB08360|2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 16315:[DB04833 DB02888] DB04833|Methaqualone CYP3A4 DB02888|FKB-001 FKBP1A common genes common pathways 16316:[DB04833 DB03766] DB04833|Methaqualone CYP3A4 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GPHN 16317:[DB04833 DB01193] DB04833|Methaqualone CYP3A4 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 16318:[DB04833 DB03552] DB04833|Methaqualone CYP3A4 DB03552|3-Tyrosine TH common genes common pathways GO:0055114| oxidation-reduction process TH;CYP3A4 16319:[DB04833 DB02464] DB04833|Methaqualone CYP3A4 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways 16320:[DB04833 DB03585] DB04833|Methaqualone CYP3A4 DB03585|Oxyphenbutazone PLA2G2E;ALB;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 16321:[DB04833 DB08208] DB04833|Methaqualone CYP3A4 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways 16322:[DB04833 DB02468] DB04833|Methaqualone CYP3A4 DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP3A4 16323:[DB04833 DB00171] DB04833|Methaqualone CYP3A4 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0008202| steroid metabolic process CYP3A4;ABCA1;PRKAA1 GO:0017144| drug metabolic process NT5C2;CYP3A4 GO:0006629| lipid metabolic process ABCA1;CYP3A4;PRKAA1;ACSL1 GO:0055114| oxidation-reduction process ABCC4;CYP3A4 16324:[DB04833 DB05766] DB04833|Methaqualone CYP3A4 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways 16325:[DB04833 DB00123] DB04833|Methaqualone CYP3A4 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways 16326:[DB04833 DB00352] DB04833|Methaqualone CYP3A4 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ABCC4 16327:[DB04833 DB00445] DB04833|Methaqualone CYP3A4 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0006629| lipid metabolic process PLA2G4A;UGT2B7;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT2B7 16328:[DB04833 DB09066] DB04833|Methaqualone CYP3A4 DB09066|Corifollitropin alfa FSHR common genes common pathways 16329:[DB04833 DB03909] DB04833|Methaqualone CYP3A4 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways 16330:[DB04833 DB02152] DB04833|Methaqualone CYP3A4 DB02152|K-252a MET;MAP2K1 common genes common pathways 16331:[DB04833 DB04875] DB04833|Methaqualone CYP3A4 DB04875|Pralnacasan CASP1 common genes common pathways 16332:[DB04833 DB09215] DB04833|Methaqualone CYP3A4 DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 16333:[DB04833 DB08205] DB04833|Methaqualone CYP3A4 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways 16334:[DB04833 DB05223] DB04833|Methaqualone CYP3A4 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways 16335:[DB04833 DB03788] DB04833|Methaqualone CYP3A4 DB03788|GC-24 THRB common genes common pathways 16336:[DB04833 DB11148] DB04833|Methaqualone CYP3A4 DB11148|Butamben CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;BCHE;ORM1;ALB common genes common pathways 16337:[DB04833 DB02678] DB04833|Methaqualone CYP3A4 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways 16338:[DB04833 DB12698] DB04833|Methaqualone CYP3A4 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways 16339:[DB04833 DB01597] DB04833|Methaqualone CYP3A4 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0006805| xenobiotic metabolic process DPEP1;CYP3A4 16340:[DB04833 DB04048] DB04833|Methaqualone CYP3A4 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PRDX2 16341:[DB04833 DB01709] DB04833|Methaqualone CYP3A4 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways 16342:[DB04833 DB00031] DB04833|Methaqualone CYP3A4 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0006629| lipid metabolic process LRP1;CYP3A4 16343:[DB04833 DB00095] DB04833|Methaqualone CYP3A4 DB00095|Efalizumab ITGAL;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 16344:[DB04833 DB09526] DB04833|Methaqualone CYP3A4 DB09526|Hydroquinone TYR;ALB common genes common pathways GO:0055114| oxidation-reduction process TYR;CYP3A4 16345:[DB04833 DB07456] DB04833|Methaqualone CYP3A4 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways 16346:[DB04833 DB08467] DB04833|Methaqualone CYP3A4 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways 16347:[DB04833 DB00642] DB04833|Methaqualone CYP3A4 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 16348:[DB04833 DB09027] DB04833|Methaqualone CYP3A4 DB09027|Ledipasvir ABCB1;ABCG2 common genes common pathways 16349:[DB04833 DB01207] DB04833|Methaqualone CYP3A4 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process TBXAS1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;TBXAS1 16350:[DB04833 DB00043] DB04833|Methaqualone CYP3A4 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways 16351:[DB04833 DB01194] DB04833|Methaqualone CYP3A4 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP3A4 16352:[DB04833 DB09343] DB04833|Methaqualone CYP3A4 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways 16353:[DB04833 DB00974] DB04833|Methaqualone CYP3A4 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1 16354:[DB04833 DB00240] DB04833|Methaqualone CYP3A4 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 16355:[DB04833 DB05282] DB04833|Methaqualone CYP3A4 DB05282|MCC AIFM1 common genes common pathways GO:0055114| oxidation-reduction process AIFM1;CYP3A4 16356:[DB04833 DB05249] DB04833|Methaqualone CYP3A4 DB05249|FavId CSF3R common genes common pathways 16357:[DB04833 DB08448] DB04833|Methaqualone CYP3A4 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 16358:[DB04833 DB03690] DB04833|Methaqualone CYP3A4 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways GO:0006629| lipid metabolic process PITPNA;CYP3A4 16359:[DB04833 DB02850] DB04833|Methaqualone CYP3A4 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HPD 16360:[DB04833 DB03608] DB04833|Methaqualone CYP3A4 DB03608|Diminazene PRDX5;PRSS1;AOC1 common genes common pathways GO:0006805| xenobiotic metabolic process AOC1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PRDX5;AOC1 16361:[DB04833 DB06600] DB04833|Methaqualone CYP3A4 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 16362:[DB04833 DB06497] DB04833|Methaqualone CYP3A4 DB06497|Aplaviroc CCR5 common genes common pathways 16363:[DB04833 DB08707] DB04833|Methaqualone CYP3A4 DB08707|4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine PIM1 common genes common pathways 16364:[DB04833 DB07717] DB04833|Methaqualone CYP3A4 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways 16365:[DB04833 DB00846] DB04833|Methaqualone CYP3A4 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 16366:[DB04833 DB06209] DB04833|Methaqualone CYP3A4 DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes CYP3A4 common pathways GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2B6;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C19;CYP2C9;CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2B6;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9;CYP2C19 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES2;CYP2C19;CYP2C9;CYP2B6 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 16367:[DB04833 DB04585] DB04833|Methaqualone CYP3A4 DB04585|DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID ARG1 common genes common pathways 16368:[DB04833 DB01125] DB04833|Methaqualone CYP3A4 DB01125|Anisindione GGCX common genes common pathways 16369:[DB04833 DB02205] DB04833|Methaqualone CYP3A4 DB02205|6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GAPDHS 16370:[DB04833 DB01606] DB04833|Methaqualone CYP3A4 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways 16371:[DB04833 DB00360] DB04833|Methaqualone CYP3A4 DB00360|Sapropterin PAH;NOS3;TH;TPH1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;TH;PTGS2;NOS3;TPH1;PAH 16372:[DB04833 DB03191] DB04833|Methaqualone CYP3A4 DB03191|3-Oxiran-2ylalanine MAT1A common genes common pathways 16373:[DB04833 DB06909] DB04833|Methaqualone CYP3A4 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways 16374:[DB04833 DB00851] DB04833|Methaqualone CYP3A4 DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0002933| CYP3A4;CYP1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;PGD;CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 16375:[DB04833 DB01009] DB04833|Methaqualone CYP3A4 DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;ABCC4;PTGS1;PTGS2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;PTGS2;CYP3A4;PTGS1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;CYP2C9;UGT1A1 16376:[DB04833 DB12095] DB04833|Methaqualone CYP3A4 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0055114| oxidation-reduction process TPH1;TPH2;CYP3A4 16377:[DB04833 DB08806] DB04833|Methaqualone CYP3A4 DB08806|Roxatidine acetate HRH2 common genes common pathways 16378:[DB04833 DB12498] DB04833|Methaqualone CYP3A4 DB12498|Mogamulizumab CXCR4 common genes common pathways 16379:[DB04833 DB00827] DB04833|Methaqualone CYP3A4 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 16380:[DB04833 DB11967] DB04833|Methaqualone CYP3A4 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2C19 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C19 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP1A2;CYP3A4 16381:[DB04833 DB00629] DB04833|Methaqualone CYP3A4 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 16382:[DB04833 DB01632] DB04833|Methaqualone CYP3A4 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways 16383:[DB04833 DB00562] DB04833|Methaqualone CYP3A4 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways 16384:[DB04833 DB02821] DB04833|Methaqualone CYP3A4 DB02821|Canaline OAT common genes common pathways 16385:[DB04833 DB01370] DB04833|Methaqualone CYP3A4 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways 16386:[DB04833 DB08800] DB04833|Methaqualone CYP3A4 DB08800|Chloropyramine HRH1 common genes common pathways 16387:[DB04833 DB07239] DB04833|Methaqualone CYP3A4 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways 16388:[DB04833 DB08384] DB04833|Methaqualone CYP3A4 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways 16389:[DB04833 DB05398] DB04833|Methaqualone CYP3A4 DB05398|C31G CD9 common genes common pathways 16390:[DB04833 DB00054] DB04833|Methaqualone CYP3A4 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways 16391:[DB04833 DB01277] DB04833|Methaqualone CYP3A4 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways 16392:[DB04833 DB00461] DB04833|Methaqualone CYP3A4 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP1A2;PTGS2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP3A4;PTGS1;MPO GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 16393:[DB04833 DB02746] DB04833|Methaqualone CYP3A4 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4;PPARD GO:0008209| androgen metabolic process ESR1;CYP3A4 16394:[DB04833 DB00892] DB04833|Methaqualone CYP3A4 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways 16395:[DB04833 DB02558] DB04833|Methaqualone CYP3A4 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways 16396:[DB04833 DB08530] DB04833|Methaqualone CYP3A4 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways 16397:[DB04833 DB13925] DB04833|Methaqualone CYP3A4 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways 16398:[DB04833 DB14060] DB04833|Methaqualone CYP3A4 DB14060|NS-398 PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 16399:[DB04833 DB01180] DB04833|Methaqualone CYP3A4 DB01180|Rescinnamine ACE common genes common pathways 16400:[DB04833 DB00310] DB04833|Methaqualone CYP3A4 DB00310|Chlorthalidone SLC12A1 common genes common pathways 16401:[DB04833 DB02170] DB04833|Methaqualone CYP3A4 DB02170|1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One CSNK2A1 common genes common pathways 16402:[DB04833 DB00975] DB04833|Methaqualone CYP3A4 DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process ABCC4;CYP3A4 16403:[DB04833 DB02512] DB04833|Methaqualone CYP3A4 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways 16404:[DB04833 DB12589] DB04833|Methaqualone CYP3A4 DB12589|Dacetuzumab CD40 common genes common pathways 16405:[DB04833 DB07106] DB04833|Methaqualone CYP3A4 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways 16406:[DB04833 DB09097] DB04833|Methaqualone CYP3A4 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways 16407:[DB04833 DB08629] DB04833|Methaqualone CYP3A4 DB08629|N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ATP5B 16408:[DB04833 DB04886] DB04833|Methaqualone CYP3A4 DB04886|Calanolide A CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 16409:[DB04833 DB05075] DB04833|Methaqualone CYP3A4 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways 16410:[DB04833 DB04736] DB04833|Methaqualone CYP3A4 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways 16411:[DB04833 DB05364] DB04833|Methaqualone CYP3A4 DB05364|ROX-888 CCL3 common genes common pathways 16412:[DB04833 DB05095] DB04833|Methaqualone CYP3A4 DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 16413:[DB04833 DB00067] DB04833|Methaqualone CYP3A4 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways 16414:[DB04833 DB00983] DB04833|Methaqualone CYP3A4 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2A6;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP2C19;CYP2C9 GO:0042737| drug catabolic process CYP2D6;CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4 16415:[DB04833 DB05204] DB04833|Methaqualone CYP3A4 DB05204|XL418 BTK common genes common pathways 16416:[DB04833 DB02902] DB04833|Methaqualone CYP3A4 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways GO:0008202| steroid metabolic process SULT1E1;CYP3A4 16417:[DB04833 DB00789] DB04833|Methaqualone CYP3A4 DB00789|Gadopentetic acid PGD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PGD 16418:[DB04833 DB07646] DB04833|Methaqualone CYP3A4 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHODH 16419:[DB04833 DB01667] DB04833|Methaqualone CYP3A4 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 16420:[DB04833 DB00282] DB04833|Methaqualone CYP3A4 DB00282|Pamidronate FDPS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 16421:[DB04833 DB00935] DB04833|Methaqualone CYP3A4 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways 16422:[DB04833 DB05016] DB04833|Methaqualone CYP3A4 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways 16423:[DB04833 DB01341] DB04833|Methaqualone CYP3A4 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways 16424:[DB04833 DB02183] DB04833|Methaqualone CYP3A4 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways 16425:[DB04833 DB00129] DB04833|Methaqualone CYP3A4 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways 16426:[DB04833 DB08868] DB04833|Methaqualone CYP3A4 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP4F12;CYP3A4;CYP4F2 GO:0055114| oxidation-reduction process CYP2E1;CYP4F12;CYP3A4;CYP4F2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 16427:[DB04833 DB00519] DB04833|Methaqualone CYP3A4 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CES1 16428:[DB04833 DB06928] DB04833|Methaqualone CYP3A4 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways 16429:[DB04833 DB06376] DB04833|Methaqualone CYP3A4 DB06376|CHGN111 CLK1 common genes common pathways 16430:[DB04833 DB12248] DB04833|Methaqualone CYP3A4 DB12248|Tulobuterol ADRB2 common genes common pathways 16431:[DB04833 DB01084] DB04833|Methaqualone CYP3A4 DB01084|Emedastine HRH1 common genes common pathways 16432:[DB04833 DB11327] DB04833|Methaqualone CYP3A4 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;NOS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 16433:[DB04833 DB00626] DB04833|Methaqualone CYP3A4 DB00626|Bacitracin IDE;A2M common genes common pathways 16434:[DB04833 DB07288] DB04833|Methaqualone CYP3A4 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways 16435:[DB04833 DB02445] DB04833|Methaqualone CYP3A4 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 16436:[DB04833 DB00583] DB04833|Methaqualone CYP3A4 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MPO;XDH;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CES1 GO:0006629| lipid metabolic process CPT2;CROT;CPT1A;CYP3A4;CRAT 16437:[DB04833 DB05944] DB04833|Methaqualone CYP3A4 DB05944|Varlitinib ERBB2;EGFR common genes common pathways 16438:[DB04833 DB05009] DB04833|Methaqualone CYP3A4 DB05009|Apadenoson ADORA2A common genes common pathways 16439:[DB04833 DB05281] DB04833|Methaqualone CYP3A4 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways 16440:[DB04833 DB11311] DB04833|Methaqualone CYP3A4 DB11311|Prothrombin FGA;FGB;F13A1;CPB2;F10 common genes common pathways 16441:[DB04833 DB08391] DB04833|Methaqualone CYP3A4 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 16442:[DB04833 DB07775] DB04833|Methaqualone CYP3A4 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways 16443:[DB04833 DB06439] DB04833|Methaqualone CYP3A4 DB06439|Tyloxapol LPL common genes common pathways GO:0006629| lipid metabolic process CYP3A4;LPL 16444:[DB04833 DB00158] DB04833|Methaqualone CYP3A4 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;MTHFR;ABCC4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 16445:[DB04833 DB12702] DB04833|Methaqualone CYP3A4 DB12702|Velusetrag HTR4 common genes common pathways 16446:[DB04833 DB03554] DB04833|Methaqualone CYP3A4 DB03554|5-Iodouracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP3A4 16447:[DB04833 DB08473] DB04833|Methaqualone CYP3A4 DB08473|5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole CSNK2A1 common genes common pathways 16448:[DB04833 DB04356] DB04833|Methaqualone CYP3A4 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 16449:[DB04833 DB08056] DB04833|Methaqualone CYP3A4 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways 16450:[DB04833 DB00376] DB04833|Methaqualone CYP3A4 DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 16451:[DB04833 DB00901] DB04833|Methaqualone CYP3A4 DB00901|Bitolterol ADRB2 common genes common pathways 16452:[DB04833 DB00692] DB04833|Methaqualone CYP3A4 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways 16453:[DB04833 DB07167] DB04833|Methaqualone CYP3A4 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways 16454:[DB04833 DB01303] DB04833|Methaqualone CYP3A4 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PDE3A GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2 16455:[DB04833 DB08341] DB04833|Methaqualone CYP3A4 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways 16456:[DB04833 DB13627] DB04833|Methaqualone CYP3A4 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 16457:[DB04833 DB05036] DB04833|Methaqualone CYP3A4 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;PTGES3 GO:0006629| lipid metabolic process CYP3A4;PTGES3 16458:[DB04833 DB07969] DB04833|Methaqualone CYP3A4 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways 16459:[DB04833 DB04249] DB04833|Methaqualone CYP3A4 DB04249|Zinc Substituted Heme C CYCS common genes common pathways GO:0055114| oxidation-reduction process CYCS;CYP3A4 16460:[DB04833 DB01890] DB04833|Methaqualone CYP3A4 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARA 16461:[DB04833 DB00535] DB04833|Methaqualone CYP3A4 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process MPO;CYP3A4 16462:[DB04833 DB05070] DB04833|Methaqualone CYP3A4 DB05070|ADX10059 GRM5 common genes common pathways 16463:[DB04833 DB05481] DB04833|Methaqualone CYP3A4 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways 16464:[DB04833 DB14520] DB04833|Methaqualone CYP3A4 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways 16465:[DB04833 DB04991] DB04833|Methaqualone CYP3A4 DB04991|XL784 ADAM10 common genes common pathways 16466:[DB04833 DB00723] DB04833|Methaqualone CYP3A4 DB00723|Methoxamine ADRA1A;ADRA1B;ADRA1D common genes common pathways 16467:[DB04833 DB00025] DB04833|Methaqualone CYP3A4 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PHYH GO:0006629| lipid metabolic process LRP1;CYP3A4 16468:[DB04833 DB01365] DB04833|Methaqualone CYP3A4 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways 16469:[DB04833 DB01157] DB04833|Methaqualone CYP3A4 DB01157|Trimetrexate DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 16470:[DB04833 DB05085] DB04833|Methaqualone CYP3A4 DB05085|TM30339 NPY4R common genes common pathways 16471:[DB04833 DB09211] DB04833|Methaqualone CYP3A4 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways 16472:[DB04833 DB00219] DB04833|Methaqualone CYP3A4 DB00219|Oxyphenonium CHRM1 common genes common pathways 16473:[DB04833 DB13928] DB04833|Methaqualone CYP3A4 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process LPL;CYP3A4 16474:[DB04833 DB06771] DB04833|Methaqualone CYP3A4 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 16475:[DB04833 DB06800] DB04833|Methaqualone CYP3A4 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways 16476:[DB04833 DB03347] DB04833|Methaqualone CYP3A4 DB03347|Triethyl Phosphate TP53 common genes common pathways 16477:[DB04833 DB00354] DB04833|Methaqualone CYP3A4 DB00354|Buclizine HRH1;CHRM1 common genes common pathways 16478:[DB04833 DB04831] DB04833|Methaqualone CYP3A4 DB04831|Tienilic acid CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 16479:[DB04833 DB05399] DB04833|Methaqualone CYP3A4 DB05399|Succinobucol VCAM1 common genes common pathways GO:0055114| oxidation-reduction process VCAM1;CYP3A4 16480:[DB04833 DB02698] DB04833|Methaqualone CYP3A4 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways 16481:[DB04833 DB02918] DB04833|Methaqualone CYP3A4 DB02918|Zardaverine PDE4D common genes common pathways 16482:[DB04833 DB01752] DB04833|Methaqualone CYP3A4 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways 16483:[DB04833 DB01970] DB04833|Methaqualone CYP3A4 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways 16484:[DB04833 DB07162] DB04833|Methaqualone CYP3A4 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways 16485:[DB04833 DB01419] DB04833|Methaqualone CYP3A4 DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4 16486:[DB04833 DB00887] DB04833|Methaqualone CYP3A4 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 16487:[DB04833 DB00756] DB04833|Methaqualone CYP3A4 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes common pathways GO:0055114| oxidation-reduction process GLUD1;CYP3A4;SDHD GO:0008209| androgen metabolic process CYP3A4;ESR1 16488:[DB04833 DB04450] DB04833|Methaqualone CYP3A4 DB04450|Heptyl 1-Thiohexopyranoside RHO;fpr;acpP common genes common pathways 16489:[DB04833 DB09325] DB04833|Methaqualone CYP3A4 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways GO:0055114| oxidation-reduction process MT-CO1;CYP3A4 16490:[DB04833 DB00115] DB04833|Methaqualone CYP3A4 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CUBN GO:0055114| oxidation-reduction process CYP3A4;MTHFR;MTRR;MMACHC GO:0008202| steroid metabolic process CUBN;CYP3A4 GO:0042359| vitamin D metabolic process CUBN;CYP3A4 16491:[DB04833 DB08257] DB04833|Methaqualone CYP3A4 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4 GO:0006629| lipid metabolic process EPHX2;CYP3A4 16492:[DB04833 DB04721] DB04833|Methaqualone CYP3A4 DB04721|N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways 16493:[DB04833 DB07991] DB04833|Methaqualone CYP3A4 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 16494:[DB04833 DB06635] DB04833|Methaqualone CYP3A4 DB06635|Otamixaban F10 common genes common pathways 16495:[DB04833 DB05298] DB04833|Methaqualone CYP3A4 DB05298|Tetomilast PDE4D common genes common pathways 16496:[DB04833 DB04339] DB04833|Methaqualone CYP3A4 DB04339|Carbocisteine GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP3A4 16497:[DB04833 DB05101] DB04833|Methaqualone CYP3A4 DB05101|Matuzumab EGFR common genes common pathways 16498:[DB04833 DB06454] DB04833|Methaqualone CYP3A4 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways 16499:[DB04833 DB14126] DB04833|Methaqualone CYP3A4 DB14126|Tenofovir ABCB1 common genes common pathways 16500:[DB04833 DB08389] DB04833|Methaqualone CYP3A4 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 16501:[DB04833 DB00677] DB04833|Methaqualone CYP3A4 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways 16502:[DB04833 DB05806] DB04833|Methaqualone CYP3A4 DB05806|Cositecan TOP1 common genes common pathways 16503:[DB04833 DB04633] DB04833|Methaqualone CYP3A4 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways 16504:[DB04833 DB13926] DB04833|Methaqualone CYP3A4 DB13926|Cenegermin NTRK1 common genes common pathways 16505:[DB04833 DB11323] DB04833|Methaqualone CYP3A4 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 16506:[DB04833 DB03957] DB04833|Methaqualone CYP3A4 DB03957|SP2456 IL2 common genes common pathways 16507:[DB04833 DB14544] DB04833|Methaqualone CYP3A4 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes CYP3A4 common pathways GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP2C8;CYP3A5 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP11B1;CYP11B2;CYP3A7;CYP3A4;CYP2C8;HSD11B2;CYP3A5;HSD3B1 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP3A7;CYP11B1;CYP11B2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 16508:[DB04833 DB14481] DB04833|Methaqualone CYP3A4 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways 16509:[DB04833 DB08102] DB04833|Methaqualone CYP3A4 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways 16510:[DB04833 DB07020] DB04833|Methaqualone CYP3A4 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways 16511:[DB04833 DB05739] DB04833|Methaqualone CYP3A4 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways 16512:[DB04833 DB05966] DB04833|Methaqualone CYP3A4 DB05966|TAS-108 ESR1;ESR2 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 16513:[DB04833 DB00017] DB04833|Methaqualone CYP3A4 DB00017|Salmon Calcitonin CALCR common genes common pathways 16514:[DB04833 DB04200] DB04833|Methaqualone CYP3A4 DB04200|Matairesinol DHRS4L2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHRS4L2 16515:[DB04833 DB08263] DB04833|Methaqualone CYP3A4 DB08263|N-(carboxycarbonyl)-D-phenylalanine HIF1AN common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HIF1AN 16516:[DB04833 DB05266] DB04833|Methaqualone CYP3A4 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0006629| lipid metabolic process PDE3A;CYP3A4 16517:[DB04833 DB08487] DB04833|Methaqualone CYP3A4 DB08487|3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways 16518:[DB04833 DB13757] DB04833|Methaqualone CYP3A4 DB13757|Epanolol CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 16519:[DB04833 DB07306] DB04833|Methaqualone CYP3A4 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 16520:[DB04833 DB01427] DB04833|Methaqualone CYP3A4 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0006629| lipid metabolic process PDE3A;CYP3A4 16521:[DB04833 DB05229] DB04833|Methaqualone CYP3A4 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0002933| CYP2C8;CYP3A4 16522:[DB04833 DB12319] DB04833|Methaqualone CYP3A4 DB12319|Benzbromarone CYP2C9;CYP2C19;CYP2C19;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;CYP2C19 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 16523:[DB04833 DB05488] DB04833|Methaqualone CYP3A4 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 16524:[DB04833 DB03577] DB04833|Methaqualone CYP3A4 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways 16525:[DB04833 DB06525] DB04833|Methaqualone CYP3A4 DB06525|Ganstigmine ACHE common genes common pathways 16526:[DB04833 DB00173] DB04833|Methaqualone CYP3A4 DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0055114| oxidation-reduction process PECR;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;PECR;ACACB 16527:[DB04833 DB00927] DB04833|Methaqualone CYP3A4 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C19;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;CYP3A4 16528:[DB04833 DB09006] DB04833|Methaqualone CYP3A4 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4;PPARD 16529:[DB04833 DB00979] DB04833|Methaqualone CYP3A4 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways 16530:[DB04833 DB07577] DB04833|Methaqualone CYP3A4 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways 16531:[DB04833 DB00928] DB04833|Methaqualone CYP3A4 DB00928|Azacitidine DNMT1;CDA common genes common pathways 16532:[DB04833 DB04847] DB04833|Methaqualone CYP3A4 DB04847|Roxadustat EGLN1;EGLN2;EGLN3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;EGLN2;EGLN1;EGLN3 16533:[DB04833 DB09369] DB04833|Methaqualone CYP3A4 DB09369|Polyestradiol phosphate ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 16534:[DB04833 DB08734] DB04833|Methaqualone CYP3A4 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways 16535:[DB04833 DB09116] DB04833|Methaqualone CYP3A4 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0055114| oxidation-reduction process CAT;CYP3A4;ALDH3B2 GO:0006629| lipid metabolic process ALDH3B2;CYP3A4 16536:[DB04833 DB09347] DB04833|Methaqualone CYP3A4 DB09347|Acetrizoic acid ALB common genes common pathways 16537:[DB04833 DB05029] DB04833|Methaqualone CYP3A4 DB05029|Lancovutide PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;CYP3A4 16538:[DB04833 DB00262] DB04833|Methaqualone CYP3A4 DB00262|Carmustine GSR;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process GSR;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 16539:[DB04833 DB08369] DB04833|Methaqualone CYP3A4 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4 GO:0055114| oxidation-reduction process CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2B6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2B6 16540:[DB04833 DB05876] DB04833|Methaqualone CYP3A4 DB05876|PDE4 PDE4A common genes common pathways 16541:[DB04833 DB06441] DB04833|Methaqualone CYP3A4 DB06441|Cangrelor P2RY12 common genes common pathways 16542:[DB04833 DB02431] DB04833|Methaqualone CYP3A4 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways 16543:[DB04833 DB09059] DB04833|Methaqualone CYP3A4 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways 16544:[DB04833 DB08805] DB04833|Methaqualone CYP3A4 DB08805|Metiamide HRH2 common genes common pathways 16545:[DB04833 DB05459] DB04833|Methaqualone CYP3A4 DB05459|Briakinumab IL12B;IL23A common genes common pathways 16546:[DB04833 DB13003] DB04833|Methaqualone CYP3A4 DB13003|Cortivazol NR3C1 common genes common pathways 16547:[DB04833 DB00914] DB04833|Methaqualone CYP3A4 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PRKAA1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;PRKAA1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 16548:[DB04833 DB07221] DB04833|Methaqualone CYP3A4 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways 16549:[DB04833 DB01956] DB04833|Methaqualone CYP3A4 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;BAAT 16550:[DB04833 DB00469] DB04833|Methaqualone CYP3A4 DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;PTGS1 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 16551:[DB04833 DB01780] DB04833|Methaqualone CYP3A4 DB01780|Fusicoccin YWHAE common genes common pathways 16552:[DB04833 DB04465] DB04833|Methaqualone CYP3A4 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways 16553:[DB04833 DB01717] DB04833|Methaqualone CYP3A4 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways 16554:[DB04833 DB07181] DB04833|Methaqualone CYP3A4 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways 16555:[DB04833 DB12887] DB04833|Methaqualone CYP3A4 DB12887|Tazemetostat EZH2 common genes common pathways 16556:[DB04833 DB05744] DB04833|Methaqualone CYP3A4 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways 16557:[DB04833 DB08078] DB04833|Methaqualone CYP3A4 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARD 16558:[DB04833 DB05867] DB04833|Methaqualone CYP3A4 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 16559:[DB04833 DB12228] DB04833|Methaqualone CYP3A4 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways 16560:[DB04833 DB00489] DB04833|Methaqualone CYP3A4 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 16561:[DB04833 DB05003] DB04833|Methaqualone CYP3A4 DB05003|Imexon RRM2;RRM1 common genes common pathways GO:0055114| oxidation-reduction process RRM1;RRM2;CYP3A4 16562:[DB04833 DB03667] DB04833|Methaqualone CYP3A4 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS1 16563:[DB04833 DB02261] DB04833|Methaqualone CYP3A4 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;GM2A 16564:[DB04833 DB00209] DB04833|Methaqualone CYP3A4 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 16565:[DB04833 DB00730] DB04833|Methaqualone CYP3A4 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A1;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0002933| CYP1A1;CYP3A4 16566:[DB04833 DB01963] DB04833|Methaqualone CYP3A4 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways 16567:[DB04833 DB03359] DB04833|Methaqualone CYP3A4 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways 16568:[DB04833 DB04978] DB04833|Methaqualone CYP3A4 DB04978|SP1049C TOP2A common genes common pathways 16569:[DB04833 DB05205] DB04833|Methaqualone CYP3A4 DB05205|CX157 MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4 16570:[DB04833 DB04090] DB04833|Methaqualone CYP3A4 DB04090|RH-1 NQO1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP3A4 16571:[DB04833 DB00761] DB04833|Methaqualone CYP3A4 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways 16572:[DB04833 DB04983] DB04833|Methaqualone CYP3A4 DB04983|Denufosol P2RY2 common genes common pathways 16573:[DB04833 DB04271] DB04833|Methaqualone CYP3A4 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 16574:[DB04833 DB11714] DB04833|Methaqualone CYP3A4 DB11714|Durvalumab CD274;CD80 common genes common pathways 16575:[DB04833 DB03753] DB04833|Methaqualone CYP3A4 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS1 16576:[DB04833 DB14025] DB04833|Methaqualone CYP3A4 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 16577:[DB04833 DB14634] DB04833|Methaqualone CYP3A4 DB14634|Fluprednidene acetate CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 16578:[DB04833 DB08455] DB04833|Methaqualone CYP3A4 DB08455|Ro 12-7310 CRABP2 common genes common pathways 16579:[DB04833 DB04690] DB04833|Methaqualone CYP3A4 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes common pathways 16580:[DB04833 DB02486] DB04833|Methaqualone CYP3A4 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways 16581:[DB04833 DB06543] DB04833|Methaqualone CYP3A4 DB06543|Astaxanthin NFKBIA common genes common pathways 16582:[DB04833 DB06994] DB04833|Methaqualone CYP3A4 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways 16583:[DB04833 DB00154] DB04833|Methaqualone CYP3A4 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 16584:[DB04833 DB00221] DB04833|Methaqualone CYP3A4 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways 16585:[DB04833 DB08908] DB04833|Methaqualone CYP3A4 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways 16586:[DB04833 DB05104] DB04833|Methaqualone CYP3A4 DB05104|Asimadoline OPRK1 common genes common pathways 16587:[DB04833 DB04297] DB04833|Methaqualone CYP3A4 DB04297|7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide HDAC8;HDAC7 common genes common pathways 16588:[DB04833 DB05013] DB04833|Methaqualone CYP3A4 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways 16589:[DB04833 DB04803] DB04833|Methaqualone CYP3A4 DB04803|Verdoheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP3A4 16590:[DB04833 DB00712] DB04833|Methaqualone CYP3A4 DB00712|Flurbiprofen PTGS1;PTGS2;CYP2C9;UGT2B7;UGT1A1;UGT1A3;UGT1A9;UGT2B4;ALB;ABCC4;SLC22A6 common genes common pathways GO:0006805| xenobiotic metabolic process UGT2B4;CYP2C9;UGT1A9;PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;UGT2B7;CYP3A4;PTGS2;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1;ABCC4;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0017144| drug metabolic process UGT1A9;UGT1A1;CYP2C9;UGT1A3;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;CYP2C9;UGT1A1 16591:[DB04833 DB05706] DB04833|Methaqualone CYP3A4 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways 16592:[DB04833 DB04487] DB04833|Methaqualone CYP3A4 DB04487|N-Methylleucine CXCL10 common genes common pathways 16593:[DB04833 DB08167] DB04833|Methaqualone CYP3A4 DB08167|Methylthioninium ACHE common genes common pathways 16594:[DB04833 DB11584] DB04833|Methaqualone CYP3A4 DB11584|Pipradrol DRD1;DRD5 common genes common pathways 16595:[DB04833 DB02123] DB04833|Methaqualone CYP3A4 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways 16596:[DB04833 DB05890] DB04833|Methaqualone CYP3A4 DB05890|VEGF-AS VEGFA common genes common pathways 16597:[DB04833 DB07779] DB04833|Methaqualone CYP3A4 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways 16598:[DB04833 DB12328] DB04833|Methaqualone CYP3A4 DB12328|Cantharidin AHR common genes common pathways GO:0006805| xenobiotic metabolic process AHR;CYP3A4 16599:[DB04833 DB08043] DB04833|Methaqualone CYP3A4 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways 16600:[DB04833 DB00817] DB04833|Methaqualone CYP3A4 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 16601:[DB04833 DB07623] DB04833|Methaqualone CYP3A4 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP3A4;CYP2A6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6 16602:[DB04833 DB07524] DB04833|Methaqualone CYP3A4 DB07524|N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine PIM1 common genes common pathways 16603:[DB04833 DB07248] DB04833|Methaqualone CYP3A4 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways 16604:[DB04833 DB00900] DB04833|Methaqualone CYP3A4 DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes common pathways 16605:[DB04833 DB03951] DB04833|Methaqualone CYP3A4 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 16606:[DB04833 DB05319] DB04833|Methaqualone CYP3A4 DB05319|Oportuzumab monatox EPCAM common genes common pathways 16607:[DB04833 DB09076] DB04833|Methaqualone CYP3A4 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 16608:[DB04833 DB08804] DB04833|Methaqualone CYP3A4 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP19A1;MAOB GO:0008209| androgen metabolic process CYP3A4;CYP19A1 16609:[DB04833 DB08516] DB04833|Methaqualone CYP3A4 DB08516|(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOB;CYP3A4 16610:[DB04833 DB00665] DB04833|Methaqualone CYP3A4 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;POR;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19;POR GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0002933| CYP2C8;CYP3A4 16611:[DB04833 DB01342] DB04833|Methaqualone CYP3A4 DB01342|Forasartan AGTR1 common genes common pathways 16612:[DB04833 DB00605] DB04833|Methaqualone CYP3A4 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0008202| steroid metabolic process AKR1B10;CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A1 GO:0002933| CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PPARD;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process CYP1A1;AKR1B1;AKR1B10;CYP3A4;PTGS2;PTGS1 16613:[DB04833 DB03796] DB04833|Methaqualone CYP3A4 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C8 GO:0006629| lipid metabolic process FABP5;PPARA;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0002933| CYP3A4;CYP2C8 16614:[DB04833 DB07847] DB04833|Methaqualone CYP3A4 DB07847|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE F10 common genes common pathways 16615:[DB04833 DB05187] DB04833|Methaqualone CYP3A4 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0006629| lipid metabolic process PPARA;CYP3A4;PPARD;PPARG 16616:[DB04833 DB05838] DB04833|Methaqualone CYP3A4 DB05838|OPC-51803 AVPR2 common genes common pathways 16617:[DB04833 DB03107] DB04833|Methaqualone CYP3A4 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways 16618:[DB04833 DB04454] DB04833|Methaqualone CYP3A4 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways 16619:[DB04833 DB06080] DB04833|Methaqualone CYP3A4 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways 16620:[DB04833 DB00651] DB04833|Methaqualone CYP3A4 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways 16621:[DB04833 DB06230] DB04833|Methaqualone CYP3A4 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;UGT2B7 GO:0017144| drug metabolic process UGT1A8;UGT1A3;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT2B7;UGT1A8 16622:[DB04833 DB06642] DB04833|Methaqualone CYP3A4 DB06642|Bevasiranib VEGFA common genes common pathways 16623:[DB04833 DB11182] DB04833|Methaqualone CYP3A4 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways 16624:[DB04833 DB08708] DB04833|Methaqualone CYP3A4 DB08708|N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine PIM1 common genes common pathways 16625:[DB04833 DB07482] DB04833|Methaqualone CYP3A4 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways 16626:[DB04833 DB03940] DB04833|Methaqualone CYP3A4 DB03940|Oxamic Acid LDHA;LDHB;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process LDHB;LDHA;CYP3A4 16627:[DB04833 DB04770] DB04833|Methaqualone CYP3A4 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways 16628:[DB04833 DB00457] DB04833|Methaqualone CYP3A4 DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0002933| CYP1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0055114| oxidation-reduction process CYP1A1;CYP3A4 16629:[DB04833 DB06813] DB04833|Methaqualone CYP3A4 DB06813|Pralatrexate DHFR;TYMS;FPGS;SLC19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 16630:[DB04833 DB08339] DB04833|Methaqualone CYP3A4 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways 16631:[DB04833 DB05362] DB04833|Methaqualone CYP3A4 DB05362|SSR-126517E F10 common genes common pathways 16632:[DB04833 DB05069] DB04833|Methaqualone CYP3A4 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways 16633:[DB04833 DB14007] DB04833|Methaqualone CYP3A4 DB14007|Pentetic acid SERPINA1 common genes common pathways 16634:[DB04833 DB08526] DB04833|Methaqualone CYP3A4 DB08526|CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE CTSH common genes common pathways 16635:[DB04833 DB06229] DB04833|Methaqualone CYP3A4 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways 16636:[DB04833 DB05630] DB04833|Methaqualone CYP3A4 DB05630|Sodium stibogluconate TOP1 common genes common pathways 16637:[DB04833 DB02527] DB04833|Methaqualone CYP3A4 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ABCC4 16638:[DB04833 DB07954] DB04833|Methaqualone CYP3A4 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways 16639:[DB04833 DB11363] DB04833|Methaqualone CYP3A4 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways 16640:[DB04833 DB05168] DB04833|Methaqualone CYP3A4 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways 16641:[DB04833 DB08889] DB04833|Methaqualone CYP3A4 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways 16642:[DB04833 DB00984] DB04833|Methaqualone CYP3A4 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP19A1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 16643:[DB04833 DB11605] DB04833|Methaqualone CYP3A4 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A5;CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;NR1I2;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0002933| CYP3A5;CYP3A7;CYP3A4 GO:0036378| CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;NR1I2;CYP3A5 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PPARA GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A7;CYP3A4;CYP3A43 16644:[DB04833 DB08602] DB04833|Methaqualone CYP3A4 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways 16645:[DB04833 DB06728] DB04833|Methaqualone CYP3A4 DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 16646:[DB04833 DB00522] DB04833|Methaqualone CYP3A4 DB00522|Bentiromide HPN common genes common pathways 16647:[DB04833 DB02004] DB04833|Methaqualone CYP3A4 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways 16648:[DB04833 DB09301] DB04833|Methaqualone CYP3A4 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways 16649:[DB04833 DB05047] DB04833|Methaqualone CYP3A4 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways 16650:[DB04833 DB07614] DB04833|Methaqualone CYP3A4 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 16651:[DB04833 DB00876] DB04833|Methaqualone CYP3A4 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways 16652:[DB04833 DB01414] DB04833|Methaqualone CYP3A4 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways 16653:[DB04833 DB03125] DB04833|Methaqualone CYP3A4 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 16654:[DB04833 DB02140] DB04833|Methaqualone CYP3A4 DB02140|N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide CTSH common genes common pathways 16655:[DB04833 DB04714] DB04833|Methaqualone CYP3A4 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 16656:[DB04833 DB09477] DB04833|Methaqualone CYP3A4 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways 16657:[DB04833 DB08795] DB04833|Methaqualone CYP3A4 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 16658:[DB04833 DB13421] DB04833|Methaqualone CYP3A4 DB13421|Edoxudine ALB common genes common pathways 16659:[DB04833 DB12023] DB04833|Methaqualone CYP3A4 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways 16660:[DB04833 DB13879] DB04833|Methaqualone CYP3A4 DB13879|Glecaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A5;UGT1A1;CYP3A4;CYP3A7 GO:0070989| oxidative demethylation CYP3A5;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0002933| CYP3A7;CYP3A4;CYP3A5 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042737| drug catabolic process CYP3A5;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP3A5 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP3A7;CYP3A43 GO:0008209| androgen metabolic process CYP3A4 16661:[DB04833 DB05423] DB04833|Methaqualone CYP3A4 DB05423|ORG-34517 NR3C1 common genes common pathways 16662:[DB04833 DB04477] DB04833|Methaqualone CYP3A4 DB04477|N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process GAPDHS;CYP3A4 16663:[DB04833 DB05415] DB04833|Methaqualone CYP3A4 DB05415|OSI-461 PDE5A common genes common pathways 16664:[DB04833 DB00431] DB04833|Methaqualone CYP3A4 DB00431|Lindane GABRB1;GLRA1;GLRA2;GLRA3;GLRB;GABRB3;GABRR1;PGR;ESR1;NR1I2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;NR1I2 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4 GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4 16665:[DB04833 DB06896] DB04833|Methaqualone CYP3A4 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways 16666:[DB04833 DB03981] DB04833|Methaqualone CYP3A4 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways 16667:[DB04833 DB07968] DB04833|Methaqualone CYP3A4 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways 16668:[DB04833 DB03987] DB04833|Methaqualone CYP3A4 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 16669:[DB04833 DB04076] DB04833|Methaqualone CYP3A4 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 16670:[DB04833 DB07403] DB04833|Methaqualone CYP3A4 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways 16671:[DB04833 DB05971] DB04833|Methaqualone CYP3A4 DB05971|Archexin AKT1 common genes common pathways 16672:[DB04833 DB06240] DB04833|Methaqualone CYP3A4 DB06240|Tariquidar ABCB1 common genes common pathways 16673:[DB04833 DB00806] DB04833|Methaqualone CYP3A4 DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 16674:[DB04833 DB01273] DB04833|Methaqualone CYP3A4 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways 16675:[DB04833 DB08856] DB04833|Methaqualone CYP3A4 DB08856|DADLE SLCO1B1 common genes common pathways 16676:[DB04833 DB07447] DB04833|Methaqualone CYP3A4 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0006629| lipid metabolic process AKR1D1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;AKR1D1 GO:0008209| androgen metabolic process CYP3A4;AKR1D1 GO:0008202| steroid metabolic process CYP3A4;AKR1D1 16677:[DB04833 DB08729] DB04833|Methaqualone CYP3A4 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways 16678:[DB04833 DB09037] DB04833|Methaqualone CYP3A4 DB09037|Pembrolizumab PDCD1 common genes common pathways 16679:[DB04833 DB00498] DB04833|Methaqualone CYP3A4 DB00498|Phenindione VKORC1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;VKORC1 GO:0055114| oxidation-reduction process CYP3A4;VKORC1 16680:[DB04833 DB08878] DB04833|Methaqualone CYP3A4 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DHFR 16681:[DB04833 DB14146] DB04833|Methaqualone CYP3A4 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways 16682:[DB04833 DB14029] DB04833|Methaqualone CYP3A4 DB14029|Furafylline CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 16683:[DB04833 DB09107] DB04833|Methaqualone CYP3A4 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways 16684:[DB04833 DB03005] DB04833|Methaqualone CYP3A4 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 16685:[DB04833 DB00159] DB04833|Methaqualone CYP3A4 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0055114| oxidation-reduction process FADS1;PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PPARA;CYP3A4;PTGS2;PPARD;PTGS1;PPARG;FADS1;ACSL3;ACSL4;TRPV1 16686:[DB04833 DB02831] DB04833|Methaqualone CYP3A4 DB02831|Dihydrogenphosphate DCXR common genes common pathways GO:0055114| oxidation-reduction process DCXR;CYP3A4 16687:[DB04833 DB00649] DB04833|Methaqualone CYP3A4 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes common pathways 16688:[DB04833 DB13200] DB04833|Methaqualone CYP3A4 DB13200|Lipegfilgrastim CSF3R common genes common pathways 16689:[DB04833 DB07406] DB04833|Methaqualone CYP3A4 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways 16690:[DB04833 DB01643] DB04833|Methaqualone CYP3A4 DB01643|Thymidine monophosphate tmk;DTYMK;dnaQ;TYMS;thyA;topA common genes common pathways 16691:[DB04833 DB00727] DB04833|Methaqualone CYP3A4 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP3A4 16692:[DB04833 DB00785] DB04833|Methaqualone CYP3A4 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways 16693:[DB04833 DB05197] DB04833|Methaqualone CYP3A4 DB05197|Sofalcone CBR1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CBR1 GO:0055114| oxidation-reduction process CBR1;CYP3A4 16694:[DB04833 DB07369] DB04833|Methaqualone CYP3A4 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways 16695:[DB04833 DB00988] DB04833|Methaqualone CYP3A4 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;MAOB;DBH;MAOA;SOD1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C19 16696:[DB04833 DB12742] DB04833|Methaqualone CYP3A4 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways 16697:[DB04833 DB02240] DB04833|Methaqualone CYP3A4 DB02240|Quinacrine mustard TPR common genes common pathways 16698:[DB04833 DB08240] DB04833|Methaqualone CYP3A4 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways 16699:[DB04833 DB06043] DB04833|Methaqualone CYP3A4 DB06043|Olaratumab PDGFRA common genes common pathways 16700:[DB04833 DB01579] DB04833|Methaqualone CYP3A4 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways 16701:[DB04833 DB05964] DB04833|Methaqualone CYP3A4 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways 16702:[DB04833 DB05129] DB04833|Methaqualone CYP3A4 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways 16703:[DB04833 DB07359] DB04833|Methaqualone CYP3A4 DB07359|3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide GCK common genes common pathways 16704:[DB04833 DB07753] DB04833|Methaqualone CYP3A4 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways 16705:[DB04833 DB07875] DB04833|Methaqualone CYP3A4 DB07875|5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide F10 common genes common pathways 16706:[DB04833 DB01034] DB04833|Methaqualone CYP3A4 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;FASN GO:0006629| lipid metabolic process FASN;CYP3A4 16707:[DB04833 DB07555] DB04833|Methaqualone CYP3A4 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways 16708:[DB04833 DB07011] DB04833|Methaqualone CYP3A4 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 16709:[DB04833 DB03867] DB04833|Methaqualone CYP3A4 DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GSR 16710:[DB04833 DB01861] DB04833|Methaqualone CYP3A4 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 16711:[DB04833 DB09137] DB04833|Methaqualone CYP3A4 DB09137|Technetium Tc-99m mebrofenin SLCO1B1;SLCO1B3 common genes common pathways 16712:[DB04833 DB04557] DB04833|Methaqualone CYP3A4 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes common pathways GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process PPARA;CYP3A4;PTGS1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;PTGS1;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 16713:[DB04833 DB09300] DB04833|Methaqualone CYP3A4 DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways 16714:[DB04833 DB02082] DB04833|Methaqualone CYP3A4 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways 16715:[DB04833 DB05831] DB04833|Methaqualone CYP3A4 DB05831|ING-1 EPCAM common genes common pathways 16716:[DB04833 DB06995] DB04833|Methaqualone CYP3A4 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways 16717:[DB04833 DB07929] DB04833|Methaqualone CYP3A4 DB07929|N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE NR1H3;RXRB common genes common pathways 16718:[DB04833 DB07479] DB04833|Methaqualone CYP3A4 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways 16719:[DB04833 DB00870] DB04833|Methaqualone CYP3A4 DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT2B7;UGT1A1;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS2;UGT2B7;PTGS1;CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP3A4;CYP2C9 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 16720:[DB04833 DB03784] DB04833|Methaqualone CYP3A4 DB03784|Elaidoylamide PLA2G2A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2A 16721:[DB04833 DB06199] DB04833|Methaqualone CYP3A4 DB06199|Atrasentan EDNRA common genes common pathways 16722:[DB04833 DB08130] DB04833|Methaqualone CYP3A4 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways 16723:[DB04833 DB00028] DB04833|Methaqualone CYP3A4 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;C3 16724:[DB04833 DB04622] DB04833|Methaqualone CYP3A4 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways 16725:[DB04833 DB06196] DB04833|Methaqualone CYP3A4 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways 16726:[DB04833 DB14057] DB04833|Methaqualone CYP3A4 DB14057|Valinomycin ABCB11 common genes common pathways 16727:[DB04833 DB06900] DB04833|Methaqualone CYP3A4 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways 16728:[DB04833 DB00218] DB04833|Methaqualone CYP3A4 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 16729:[DB04833 DB13530] DB04833|Methaqualone CYP3A4 DB13530|Mepindolol CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 16730:[DB04833 DB08842] DB04833|Methaqualone CYP3A4 DB08842|Acetylcarnitine SLC22A5 common genes common pathways 16731:[DB04833 DB03708] DB04833|Methaqualone CYP3A4 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways 16732:[DB04833 DB05199] DB04833|Methaqualone CYP3A4 DB05199|LX1031 TPH1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TPH1 16733:[DB04833 DB05882] DB04833|Methaqualone CYP3A4 DB05882|CHF 4227 ESR1;ESR2 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 16734:[DB04833 DB08249] DB04833|Methaqualone CYP3A4 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 16735:[DB04833 DB13165] DB04833|Methaqualone CYP3A4 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways 16736:[DB04833 DB03346] DB04833|Methaqualone CYP3A4 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0008202| steroid metabolic process SULT1E1;CYP3A4 16737:[DB04833 DB00686] DB04833|Methaqualone CYP3A4 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways 16738:[DB04833 DB07208] DB04833|Methaqualone CYP3A4 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 16739:[DB04833 DB09093] DB04833|Methaqualone CYP3A4 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways 16740:[DB04833 DB07744] DB04833|Methaqualone CYP3A4 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways 16741:[DB04833 DB13443] DB04833|Methaqualone CYP3A4 DB13443|Esatenolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 16742:[DB04833 DB05642] DB04833|Methaqualone CYP3A4 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways 16743:[DB04833 DB08584] DB04833|Methaqualone CYP3A4 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways 16744:[DB04833 DB04859] DB04833|Methaqualone CYP3A4 DB04859|Zanapezil ACHE common genes common pathways 16745:[DB04833 DB12548] DB04833|Methaqualone CYP3A4 DB12548|Sparsentan AGT;EDNRA common genes common pathways 16746:[DB04833 DB00245] DB04833|Methaqualone CYP3A4 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6;CYP2C19 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 16747:[DB04833 DB07269] DB04833|Methaqualone CYP3A4 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 16748:[DB04833 DB00792] DB04833|Methaqualone CYP3A4 DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 16749:[DB04833 DB14070] DB04833|Methaqualone CYP3A4 DB14070|HM-30181 ABCB1 common genes common pathways 16750:[DB04833 DB07115] DB04833|Methaqualone CYP3A4 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 16751:[DB04833 DB03477] DB04833|Methaqualone CYP3A4 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 16752:[DB04833 DB05295] DB04833|Methaqualone CYP3A4 DB05295|Eldecalcitol VDR common genes common pathways 16753:[DB04833 DB08566] DB04833|Methaqualone CYP3A4 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 16754:[DB04833 DB08935] DB04833|Methaqualone CYP3A4 DB08935|Obinutuzumab MS4A1 common genes common pathways 16755:[DB04833 DB03878] DB04833|Methaqualone CYP3A4 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways 16756:[DB04833 DB05131] DB04833|Methaqualone CYP3A4 DB05131|TTP889 F9 common genes common pathways 16757:[DB04833 DB09257] DB04833|Methaqualone CYP3A4 DB09257|Gimeracil DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;DPYD 16758:[DB04833 DB07328] DB04833|Methaqualone CYP3A4 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways 16759:[DB04833 DB08705] DB04833|Methaqualone CYP3A4 DB08705|6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE PIM1 common genes common pathways 16760:[DB04833 DB03434] DB04833|Methaqualone CYP3A4 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways 16761:[DB04833 DB00429] DB04833|Methaqualone CYP3A4 DB00429|Carboprost tromethamine PTGER1 common genes common pathways 16762:[DB04833 DB07899] DB04833|Methaqualone CYP3A4 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways 16763:[DB04833 DB09546] DB04833|Methaqualone CYP3A4 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways 16764:[DB04833 DB08964] DB04833|Methaqualone CYP3A4 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways 16765:[DB04833 DB00981] DB04833|Methaqualone CYP3A4 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways 16766:[DB04833 DB05507] DB04833|Methaqualone CYP3A4 DB05507|VX-765 CASP1;IL1B common genes common pathways 16767:[DB04833 DB01133] DB04833|Methaqualone CYP3A4 DB01133|Tiludronic acid ATP6V1A;PTPN1 common genes common pathways 16768:[DB04833 DB08879] DB04833|Methaqualone CYP3A4 DB08879|Belimumab TNFSF13B common genes common pathways 16769:[DB04833 DB02134] DB04833|Methaqualone CYP3A4 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 16770:[DB04833 DB07846] DB04833|Methaqualone CYP3A4 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways 16771:[DB04833 DB06550] DB04833|Methaqualone CYP3A4 DB06550|Bivatuzumab CD44 common genes common pathways 16772:[DB04833 DB05804] DB04833|Methaqualone CYP3A4 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0002933| CYP3A7;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP3A7 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0055114| oxidation-reduction process CYP19A1;CYP3A7;PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7 16773:[DB04833 DB00970] DB04833|Methaqualone CYP3A4 DB00970|Dactinomycin TOP2A;TOP2B;SLC22A5;ABCB1;ABCC6;ABCC1;ABCG2 common genes common pathways 16774:[DB04833 DB04144] DB04833|Methaqualone CYP3A4 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways 16775:[DB04833 DB07430] DB04833|Methaqualone CYP3A4 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways 16776:[DB04833 DB03639] DB04833|Methaqualone CYP3A4 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways 16777:[DB04833 DB11133] DB04833|Methaqualone CYP3A4 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;PPARA;CYP3A4;PPARG;SREBF1 GO:0008202| steroid metabolic process SREBF1;CYP3A4 16778:[DB04833 DB01325] DB04833|Methaqualone CYP3A4 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways 16779:[DB04833 DB04537] DB04833|Methaqualone CYP3A4 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways 16780:[DB04833 DB13934] DB04833|Methaqualone CYP3A4 DB13934|Ligandrol AR common genes common pathways 16781:[DB04833 DB04985] DB04833|Methaqualone CYP3A4 DB04985|Tigapotide RPSA common genes common pathways 16782:[DB04833 DB01162] DB04833|Methaqualone CYP3A4 DB01162|Terazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ABCB1 common genes common pathways 16783:[DB04833 DB05141] DB04833|Methaqualone CYP3A4 DB05141|LY2181308 BIRC5 common genes common pathways 16784:[DB04833 DB00058] DB04833|Methaqualone CYP3A4 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways 16785:[DB04833 DB04398] DB04833|Methaqualone CYP3A4 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 16786:[DB04833 DB13174] DB04833|Methaqualone CYP3A4 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP3A4;CYP3A7 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP2E1;CYP3A7;CYP1A2;ALOX5;CYP3A43 GO:0042738| exogenous drug catabolic process CYP2C9;CYP1A2;CYP3A4 16787:[DB04833 DB05099] DB04833|Methaqualone CYP3A4 DB05099|Ancrod FGA common genes common pathways 16788:[DB04833 DB11359] DB04833|Methaqualone CYP3A4 DB11359|Guaiacol ALB common genes common pathways 16789:[DB04833 DB07161] DB04833|Methaqualone CYP3A4 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways 16790:[DB04833 DB03677] DB04833|Methaqualone CYP3A4 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4 16791:[DB04833 DB11738] DB04833|Methaqualone CYP3A4 DB11738|Rilmenidine ADRA2A common genes common pathways 16792:[DB04833 DB08009] DB04833|Methaqualone CYP3A4 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways 16793:[DB04833 DB02530] DB04833|Methaqualone CYP3A4 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways 16794:[DB04833 DB05879] DB04833|Methaqualone CYP3A4 DB05879|AME-527 TNF common genes common pathways 16795:[DB04833 DB11186] DB04833|Methaqualone CYP3A4 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes common pathways 16796:[DB04833 DB08325] DB04833|Methaqualone CYP3A4 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways 16797:[DB04833 DB07449] DB04833|Methaqualone CYP3A4 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 16798:[DB04833 DB01279] DB04833|Methaqualone CYP3A4 DB01279|Galsulfase PLIN3 common genes common pathways 16799:[DB04833 DB00388] DB04833|Methaqualone CYP3A4 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;MAOA;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 16800:[DB04833 DB07933] DB04833|Methaqualone CYP3A4 DB07933|Erteberel ESR2;ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 16801:[DB04833 DB00284] DB04833|Methaqualone CYP3A4 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 16802:[DB04833 DB01401] DB04833|Methaqualone CYP3A4 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;CYP3A4;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 16803:[DB04833 DB09085] DB04833|Methaqualone CYP3A4 DB09085|Tetracaine RYR1;RYR2 common genes common pathways 16804:[DB04833 DB06560] DB04833|Methaqualone CYP3A4 DB06560|Pascolizumab IL4 common genes common pathways 16805:[DB04833 DB05889] DB04833|Methaqualone CYP3A4 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways 16806:[DB04833 DB05367] DB04833|Methaqualone CYP3A4 DB05367|Actelion-1 EDNRA common genes common pathways 16807:[DB04833 DB01004] DB04833|Methaqualone CYP3A4 DB01004|Ganciclovir SLC22A1;SLC22A6;SLC22A8;SLC22A7;SLC47A1;SLC47A2 common genes common pathways 16808:[DB04833 DB08499] DB04833|Methaqualone CYP3A4 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways 16809:[DB04833 DB01013] DB04833|Methaqualone CYP3A4 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP1A1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 16810:[DB04833 DB08880] DB04833|Methaqualone CYP3A4 DB08880|Teriflunomide DHODH;CYP2C8;CYP1A2;ABCG2;SLCO1B1 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2C8 GO:0002933| CYP3A4;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C8;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4;DHODH 16811:[DB04833 DB12020] DB04833|Methaqualone CYP3A4 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 16812:[DB04833 DB06235] DB04833|Methaqualone CYP3A4 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT2B7 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A9 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;UGT1A9 GO:0006629| lipid metabolic process UGT2B7;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 16813:[DB04833 DB04971] DB04833|Methaqualone CYP3A4 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;PPARA;CYP3A4 16814:[DB04833 DB00337] DB04833|Methaqualone CYP3A4 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 16815:[DB04833 DB01340] DB04833|Methaqualone CYP3A4 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways 16816:[DB04833 DB01177] DB04833|Methaqualone CYP3A4 DB01177|Idarubicin TOP2A;CYP2C9;CYP2D6;ABCC1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2D6 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2D6 16817:[DB04833 DB01042] DB04833|Methaqualone CYP3A4 DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways 16818:[DB04833 DB05297] DB04833|Methaqualone CYP3A4 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways 16819:[DB04833 DB03738] DB04833|Methaqualone CYP3A4 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 16820:[DB04833 DB00009] DB04833|Methaqualone CYP3A4 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 16821:[DB04833 DB08890] DB04833|Methaqualone CYP3A4 DB08890|Linaclotide GUCY2C common genes common pathways 16822:[DB04833 DB11134] DB04833|Methaqualone CYP3A4 DB11134|Cupric oxide ALB;CP common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CP 16823:[DB04833 DB07285] DB04833|Methaqualone CYP3A4 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 16824:[DB04833 DB03390] DB04833|Methaqualone CYP3A4 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways 16825:[DB04833 DB07419] DB04833|Methaqualone CYP3A4 DB07419|S-23 AR common genes common pathways 16826:[DB04833 DB04689] DB04833|Methaqualone CYP3A4 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 16827:[DB04833 DB04577] DB04833|Methaqualone CYP3A4 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways 16828:[DB04833 DB07069] DB04833|Methaqualone CYP3A4 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 16829:[DB04833 DB07728] DB04833|Methaqualone CYP3A4 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 16830:[DB04833 DB00509] DB04833|Methaqualone CYP3A4 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;TPO 16831:[DB04833 DB11118] DB04833|Methaqualone CYP3A4 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways 16832:[DB04833 DB01809] DB04833|Methaqualone CYP3A4 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways 16833:[DB04833 DB00833] DB04833|Methaqualone CYP3A4 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MPO 16834:[DB04833 DB01765] DB04833|Methaqualone CYP3A4 DB01765|(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid CSNK2A1 common genes common pathways 16835:[DB04833 DB00554] DB04833|Methaqualone CYP3A4 DB00554|Piroxicam PTGS2;PTGS1;CYP2C9;CYP2C8;ALB;SLC22A6;SLC22A8;SLC22A11;SLCO2B1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;CYP2C9;CYP2C8 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1;CYP2C9;CYP2C8 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2C8 GO:0002933| CYP3A4;CYP2C8 16836:[DB04833 DB01549] DB04833|Methaqualone CYP3A4 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways 16837:[DB04833 DB06788] DB04833|Methaqualone CYP3A4 DB06788|Histrelin GNRHR common genes common pathways 16838:[DB04833 DB03612] DB04833|Methaqualone CYP3A4 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0055114| oxidation-reduction process HADH;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;HADH 16839:[DB04833 DB08399] DB04833|Methaqualone CYP3A4 DB08399|PICEATANNOL ATP5B common genes common pathways GO:0006629| lipid metabolic process ATP5B;CYP3A4 16840:[DB04833 DB02457] DB04833|Methaqualone CYP3A4 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;LIPF GO:0006629| lipid metabolic process LIPF;CYP3A4 16841:[DB04833 DB04057] DB04833|Methaqualone CYP3A4 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways 16842:[DB04833 DB08831] DB04833|Methaqualone CYP3A4 DB08831|2-deoxyglucose SLC2A1 common genes common pathways 16843:[DB04833 DB12323] DB04833|Methaqualone CYP3A4 DB12323|Radotinib ABL1 common genes common pathways 16844:[DB04833 DB01840] DB04833|Methaqualone CYP3A4 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ISYNA1 16845:[DB04833 DB02358] DB04833|Methaqualone CYP3A4 DB02358|LY374571 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MTHFD1 16846:[DB04833 DB04864] DB04833|Methaqualone CYP3A4 DB04864|Huperzine A ACHE common genes common pathways 16847:[DB04833 DB11693] DB04833|Methaqualone CYP3A4 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 16848:[DB04833 DB06834] DB04833|Methaqualone CYP3A4 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways 16849:[DB04833 DB00161] DB04833|Methaqualone CYP3A4 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways 16850:[DB04833 DB06612] DB04833|Methaqualone CYP3A4 DB06612|Mepolizumab IL5 common genes common pathways 16851:[DB04833 DB05152] DB04833|Methaqualone CYP3A4 DB05152|NGX267 CHRM1 common genes common pathways 16852:[DB04833 DB01931] DB04833|Methaqualone CYP3A4 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways 16853:[DB04833 DB04954] DB04833|Methaqualone CYP3A4 DB04954|Tecadenoson ADORA1 common genes common pathways 16854:[DB04833 DB02659] DB04833|Methaqualone CYP3A4 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP3A4 GO:0006629| lipid metabolic process PLA2G1B;FABP6;CYP3A4 GO:0055114| oxidation-reduction process MT-CO1;MT-CO2;CYP3A4;ABCC4;ADH1C 16855:[DB04833 DB05110] DB04833|Methaqualone CYP3A4 DB05110|VIR201 IFNG common genes common pathways 16856:[DB04833 DB04307] DB04833|Methaqualone CYP3A4 DB04307|5-Hydroxy-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOB 16857:[DB04833 DB04899] DB04833|Methaqualone CYP3A4 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways 16858:[DB04833 DB00432] DB04833|Methaqualone CYP3A4 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways 16859:[DB04833 DB06194] DB04833|Methaqualone CYP3A4 DB06194|Elocalcitol VDR common genes common pathways 16860:[DB04833 DB12116] DB04833|Methaqualone CYP3A4 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;AHR 16861:[DB04833 DB02104] DB04833|Methaqualone CYP3A4 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 16862:[DB04833 DB05846] DB04833|Methaqualone CYP3A4 DB05846|Mito-4509 APP common genes common pathways 16863:[DB04833 DB08802] DB04833|Methaqualone CYP3A4 DB08802|Isothipendyl HRH1 common genes common pathways 16864:[DB04833 DB02035] DB04833|Methaqualone CYP3A4 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways 16865:[DB04833 DB13919] DB04833|Methaqualone CYP3A4 DB13919|Candesartan AGTR1;CYP2C8;CYP2C9;UGT1A3;PTGS1;ABCB1;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4;PTGS1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process PTGS1;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;PTGS1;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0002933| CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A3;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4 16866:[DB04833 DB04891] DB04833|Methaqualone CYP3A4 DB04891|Becocalcidiol MED1;VDR common genes common pathways 16867:[DB04833 DB00610] DB04833|Methaqualone CYP3A4 DB00610|Metaraminol ADRA1A common genes common pathways 16868:[DB04833 DB02597] DB04833|Methaqualone CYP3A4 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways 16869:[DB04833 DB02309] DB04833|Methaqualone CYP3A4 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 16870:[DB04833 DB13978] DB04833|Methaqualone CYP3A4 DB13978|Selisistat SIRT1 common genes common pathways 16871:[DB04833 DB02547] DB04833|Methaqualone CYP3A4 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 16872:[DB04833 DB06429] DB04833|Methaqualone CYP3A4 DB06429|Talnetant TACR3 common genes common pathways 16873:[DB04833 DB04932] DB04833|Methaqualone CYP3A4 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways 16874:[DB04833 DB00644] DB04833|Methaqualone CYP3A4 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways 16875:[DB04833 DB04927] DB04833|Methaqualone CYP3A4 DB04927|NM100060 SQLE common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SQLE 16876:[DB04833 DB14543] DB04833|Methaqualone CYP3A4 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes CYP3A4 common pathways GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;HSD3B1;HSD11B2;CYP3A5;CYP11B2;CYP11B1;CYP3A7;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP11B2;CYP11B1 GO:0006706| steroid catabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP2C8;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2C8 GO:0070989| oxidative demethylation CYP3A4;CYP3A5;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP11B2;CYP11B1;CYP3A7;CYP2C8;CYP3A5 16877:[DB04833 DB07641] DB04833|Methaqualone CYP3A4 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOA 16878:[DB04833 DB04235] DB04833|Methaqualone CYP3A4 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways 16879:[DB04833 DB00389] DB04833|Methaqualone CYP3A4 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process TPO;CYP19A1;CYP3A4 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 16880:[DB04833 DB01164] DB04833|Methaqualone CYP3A4 DB01164|Calcium Chloride S100A13 common genes common pathways 16881:[DB04833 DB08703] DB04833|Methaqualone CYP3A4 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways 16882:[DB04833 DB09283] DB04833|Methaqualone CYP3A4 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0006629| lipid metabolic process PDE3A;CYP3A4 16883:[DB04833 DB06941] DB04833|Methaqualone CYP3A4 DB06941|(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide S100B common genes common pathways 16884:[DB04833 DB01482] DB04833|Methaqualone CYP3A4 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 16885:[DB04833 DB01297] DB04833|Methaqualone CYP3A4 DB01297|Practolol ADRB1;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 16886:[DB04833 DB11772] DB04833|Methaqualone CYP3A4 DB11772|Pilaralisib PIK3CA common genes common pathways 16887:[DB04833 DB14067] DB04833|Methaqualone CYP3A4 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways 16888:[DB04833 DB02095] DB04833|Methaqualone CYP3A4 DB02095|Isatin MAOB;MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOB;CYP3A4 16889:[DB04833 DB09568] DB04833|Methaqualone CYP3A4 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP4F2 GO:0070989| oxidative demethylation CYP3A4;CYP3A5 GO:0055114| oxidation-reduction process CYP3A5;CYP4F2;HSD17B10;CYP3A4;HADH;CYP3A7;CYP3A43 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4;HADH;HSD17B10;DGAT2;ELOVL4;ECHS1;LPL GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP3A5 16890:[DB04833 DB11994] DB04833|Methaqualone CYP3A4 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process ALOX5;CYP3A43;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP3A7;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4 16891:[DB04833 DB00491] DB04833|Methaqualone CYP3A4 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 16892:[DB04833 DB04556] DB04833|Methaqualone CYP3A4 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways 16893:[DB04833 DB09008] DB04833|Methaqualone CYP3A4 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways 16894:[DB04833 DB06436] DB04833|Methaqualone CYP3A4 DB06436|Semaxanib KDR;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 16895:[DB04833 DB04970] DB04833|Methaqualone CYP3A4 DB04970|Lesopitron HTR1A common genes common pathways 16896:[DB04833 DB00335] DB04833|Methaqualone CYP3A4 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 16897:[DB04833 DB06867] DB04833|Methaqualone CYP3A4 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways 16898:[DB04833 DB07412] DB04833|Methaqualone CYP3A4 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways 16899:[DB04833 DB01681] DB04833|Methaqualone CYP3A4 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways 16900:[DB04833 DB08492] DB04833|Methaqualone CYP3A4 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;ALOX15 GO:0055114| oxidation-reduction process CYP3A4;ALOX15 16901:[DB04833 DB02504] DB04833|Methaqualone CYP3A4 DB02504|[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;CYP3A4 16902:[DB04833 DB00015] DB04833|Methaqualone CYP3A4 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 16903:[DB04833 DB08651] DB04833|Methaqualone CYP3A4 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways 16904:[DB04833 DB07271] DB04833|Methaqualone CYP3A4 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways 16905:[DB04833 DB09013] DB04833|Methaqualone CYP3A4 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 16906:[DB04833 DB03181] DB04833|Methaqualone CYP3A4 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways 16907:[DB04833 DB09302] DB04833|Methaqualone CYP3A4 DB09302|Alirocumab PCSK9 common genes common pathways GO:0006629| lipid metabolic process PCSK9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;PCSK9 16908:[DB04833 DB03906] DB04833|Methaqualone CYP3A4 DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;HMOX1 16909:[DB04833 DB13044] DB04833|Methaqualone CYP3A4 DB13044|Gossypol BCL2L1 common genes common pathways 16910:[DB04833 DB12789] DB04833|Methaqualone CYP3A4 DB12789|Dinoprost PTGDR2 common genes common pathways 16911:[DB04833 DB01852] DB04833|Methaqualone CYP3A4 DB01852|Kaempherol UGT3A1 common genes common pathways 16912:[DB04833 DB02235] DB04833|Methaqualone CYP3A4 DB02235|L-methionine (R)-S-oxide APP common genes common pathways 16913:[DB04833 DB03551] DB04833|Methaqualone CYP3A4 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways 16914:[DB04833 DB05073] DB04833|Methaqualone CYP3A4 DB05073|SRT501 SIRT1 common genes common pathways 16915:[DB04833 DB07950] DB04833|Methaqualone CYP3A4 DB07950|Indoleacetic acid PLA2G2E;SKP1;CCBL1 common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;CYP3A4 16916:[DB04833 DB05010] DB04833|Methaqualone CYP3A4 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways 16917:[DB04833 DB05374] DB04833|Methaqualone CYP3A4 DB05374|Rindopepimut EGFR common genes common pathways 16918:[DB04833 DB00089] DB04833|Methaqualone CYP3A4 DB00089|Capromab pendetide FOLH1 common genes common pathways 16919:[DB04833 DB04583] DB04833|Methaqualone CYP3A4 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 16920:[DB04833 DB01675] DB04833|Methaqualone CYP3A4 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;ACAD8 GO:0006629| lipid metabolic process ACAD8;CYP3A4 16921:[DB04833 DB09326] DB04833|Methaqualone CYP3A4 DB09326|Ammonia N-13 NAGS;RHCG common genes common pathways 16922:[DB04833 DB00894] DB04833|Methaqualone CYP3A4 DB00894|Testolactone CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 16923:[DB04833 DB07457] DB04833|Methaqualone CYP3A4 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways 16924:[DB04833 DB07970] DB04833|Methaqualone CYP3A4 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways 16925:[DB04833 DB07844] DB04833|Methaqualone CYP3A4 DB07844|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways 16926:[DB04833 DB07051] DB04833|Methaqualone CYP3A4 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways 16927:[DB04833 DB08207] DB04833|Methaqualone CYP3A4 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways 16928:[DB04833 DB00086] DB04833|Methaqualone CYP3A4 DB00086|Streptokinase PLG;F2R;PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;CYP3A4 16929:[DB04833 DB06795] DB04833|Methaqualone CYP3A4 DB06795|Mafenide CA6 common genes common pathways 16930:[DB04833 DB00447] DB04833|Methaqualone CYP3A4 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways 16931:[DB04833 DB05854] DB04833|Methaqualone CYP3A4 DB05854|CLX-0921 PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 16932:[DB04833 DB00492] DB04833|Methaqualone CYP3A4 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways 16933:[DB04833 DB00986] DB04833|Methaqualone CYP3A4 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways 16934:[DB04833 DB05443] DB04833|Methaqualone CYP3A4 DB05443|ADL 10-0101 OPRK1 common genes common pathways 16935:[DB04833 DB05098] DB04833|Methaqualone CYP3A4 DB05098|Leptin LEPR common genes common pathways 16936:[DB04833 DB00217] DB04833|Methaqualone CYP3A4 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways 16937:[DB04833 DB09344] DB04833|Methaqualone CYP3A4 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways 16938:[DB04833 DB12202] DB04833|Methaqualone CYP3A4 DB12202|Zalutumumab EGFR common genes common pathways 16939:[DB04833 DB00709] DB04833|Methaqualone CYP3A4 DB00709|Lamivudine pol;DCK;CMPK1;PGK1;NME1;NME2;PCYT1A;PCYT2;NT5C;ALB;ABCC1;SLC22A6;ABCG2;SLC22A1;SLC22A2;SLC22A3;ABCB1;ABCC4;ABCC3;ABCC2 common genes common pathways GO:0006629| lipid metabolic process PCYT2;PCYT1A;CYP3A4 GO:0055114| oxidation-reduction process ABCC4;CYP3A4 16940:[DB04833 DB01090] DB04833|Methaqualone CYP3A4 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 16941:[DB04833 DB12140] DB04833|Methaqualone CYP3A4 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways 16942:[DB04833 DB08520] DB04833|Methaqualone CYP3A4 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways 16943:[DB04833 DB01291] DB04833|Methaqualone CYP3A4 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways 16944:[DB04833 DB02054] DB04833|Methaqualone CYP3A4 DB02054|Gabaculine OAT common genes common pathways 16945:[DB04833 DB01646] DB04833|Methaqualone CYP3A4 DB01646|N-Acetylmethionine RHO common genes common pathways 16946:[DB04833 DB01088] DB04833|Methaqualone CYP3A4 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways 16947:[DB04833 DB02884] DB04833|Methaqualone CYP3A4 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways 16948:[DB04833 DB08575] DB04833|Methaqualone CYP3A4 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways 16949:[DB04833 DB08085] DB04833|Methaqualone CYP3A4 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways 16950:[DB04833 DB07802] DB04833|Methaqualone CYP3A4 DB07802|3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE CSNK2A1 common genes common pathways 16951:[DB04833 DB08356] DB04833|Methaqualone CYP3A4 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways 16952:[DB04833 DB00544] DB04833|Methaqualone CYP3A4 DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0002933| CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP3A4;CYP2A6;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP1A2;CYP2C8;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP2A6;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process DPYD;ABCC4;CYP1A2;MTHFR;CYP3A4;CYP2A6;CYP2C8;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 16953:[DB04833 DB09149] DB04833|Methaqualone CYP3A4 DB09149|Florbetapir (18F) APP common genes common pathways 16954:[DB04833 DB00542] DB04833|Methaqualone CYP3A4 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MTHFR 16955:[DB04833 DB00742] DB04833|Methaqualone CYP3A4 DB00742|Mannitol ABCB1 common genes common pathways 16956:[DB04833 DB13261] DB04833|Methaqualone CYP3A4 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 16957:[DB04833 DB01790] DB04833|Methaqualone CYP3A4 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways 16958:[DB04833 DB08565] DB04833|Methaqualone CYP3A4 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 16959:[DB04833 DB03471] DB04833|Methaqualone CYP3A4 DB03471|6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2A 16960:[DB04833 DB07749] DB04833|Methaqualone CYP3A4 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways 16961:[DB04833 DB09120] DB04833|Methaqualone CYP3A4 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP3A4 GO:0006629| lipid metabolic process TRPV1;CYP2C9;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0042737| drug catabolic process CYP2C9;CYP3A4;CYP1A2 16962:[DB04833 DB06116] DB04833|Methaqualone CYP3A4 DB06116|Eldelumab CXCL10 common genes common pathways 16963:[DB04833 DB05848] DB04833|Methaqualone CYP3A4 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways 16964:[DB04833 DB04036] DB04833|Methaqualone CYP3A4 DB04036|Coenzyme a Persulfide IVD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;IVD 16965:[DB04833 DB07240] DB04833|Methaqualone CYP3A4 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways 16966:[DB04833 DB00143] DB04833|Methaqualone CYP3A4 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0055114| oxidation-reduction process AKR1B1;GPX7;GPX6;MGST1;GSR;GPX3;GPX5;CYP3A4;GSTO1;GPX8;GPX4;GLRX;GSTK1;GPX2;TXNDC12;GLRX2;GPX1;ABCC4;GSTO2 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process GSTO2;MGST3;MGST2;GGT1;CYP3A4;GSTA4;GSTP1;MGST1 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process HPGDS;GPX1;MGST3;MGST2;CYP3A4;GPX5 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 16967:[DB04833 DB03176] DB04833|Methaqualone CYP3A4 DB03176|KB-141 THRB;THRA common genes common pathways 16968:[DB04833 DB01785] DB04833|Methaqualone CYP3A4 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0006629| lipid metabolic process CYP3A4;IDI1;FDPS GO:0008202| steroid metabolic process FDPS;IDI1;CYP3A4 16969:[DB04833 DB14039] DB04833|Methaqualone CYP3A4 DB14039|Erenumab CALCRL common genes common pathways 16970:[DB04833 DB03683] DB04833|Methaqualone CYP3A4 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 16971:[DB04833 DB03393] DB04833|Methaqualone CYP3A4 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways 16972:[DB04833 DB01025] DB04833|Methaqualone CYP3A4 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways GO:0006805| xenobiotic metabolic process S100A12;CYP3A4 16973:[DB04833 DB03744] DB04833|Methaqualone CYP3A4 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways 16974:[DB04833 DB01613] DB04833|Methaqualone CYP3A4 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways 16975:[DB04833 DB01413] DB04833|Methaqualone CYP3A4 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 16976:[DB04833 DB02016] DB04833|Methaqualone CYP3A4 DB02016|R048-8071 LSS common genes common pathways GO:0006629| lipid metabolic process LSS;CYP3A4 16977:[DB04833 DB02211] DB04833|Methaqualone CYP3A4 DB02211|N-Methyl-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOB;CYP3A4 16978:[DB04833 DB01878] DB04833|Methaqualone CYP3A4 DB01878|Benzophenone ESR1;ESR2 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 16979:[DB04833 DB03070] DB04833|Methaqualone CYP3A4 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process IMPDH2;CYP3A4 16980:[DB04833 DB09212] DB04833|Methaqualone CYP3A4 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 16981:[DB04833 DB06089] DB04833|Methaqualone CYP3A4 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways 16982:[DB04833 DB00012] DB04833|Methaqualone CYP3A4 DB00012|Darbepoetin alfa EPOR common genes common pathways 16983:[DB04833 DB03929] DB04833|Methaqualone CYP3A4 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways 16984:[DB04833 DB08100] DB04833|Methaqualone CYP3A4 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways 16985:[DB04833 DB04673] DB04833|Methaqualone CYP3A4 DB04673|4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE F10 common genes common pathways 16986:[DB04833 DB04924] DB04833|Methaqualone CYP3A4 DB04924|Itopride DRD2;ACHE common genes common pathways 16987:[DB04833 DB12455] DB04833|Methaqualone CYP3A4 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways 16988:[DB04833 DB00774] DB04833|Methaqualone CYP3A4 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways 16989:[DB04833 DB04322] DB04833|Methaqualone CYP3A4 DB04322|LY249543 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MTHFD1 16990:[DB04833 DB04575] DB04833|Methaqualone CYP3A4 DB04575|Quinestrol ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 16991:[DB04833 DB06350] DB04833|Methaqualone CYP3A4 DB06350|Elinogrel P2RY12 common genes common pathways 16992:[DB04833 DB08039] DB04833|Methaqualone CYP3A4 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways 16993:[DB04833 DB13985] DB04833|Methaqualone CYP3A4 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways 16994:[DB04833 DB04615] DB04833|Methaqualone CYP3A4 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways 16995:[DB04833 DB00480] DB04833|Methaqualone CYP3A4 DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 16996:[DB04833 DB04376] DB04833|Methaqualone CYP3A4 DB04376|13-Acetylphorbol PRKCD common genes common pathways 16997:[DB04833 DB07021] DB04833|Methaqualone CYP3A4 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways 16998:[DB04833 DB07202] DB04833|Methaqualone CYP3A4 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways 16999:[DB04833 DB08791] DB04833|Methaqualone CYP3A4 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways 17000:[DB04833 DB00107] DB04833|Methaqualone CYP3A4 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways 17001:[DB04833 DB00177] DB04833|Methaqualone CYP3A4 DB00177|Valsartan AGTR1;CYP2C9;ALB;SLCO1B3;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 17002:[DB04833 DB09214] DB04833|Methaqualone CYP3A4 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS2;CYP3A4;PTGS1 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;PTGS2 17003:[DB04833 DB00659] DB04833|Methaqualone CYP3A4 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways 17004:[DB04833 DB05540] DB04833|Methaqualone CYP3A4 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways 17005:[DB04833 DB03331] DB04833|Methaqualone CYP3A4 DB03331|N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GAPDHS 17006:[DB04833 DB09043] DB04833|Methaqualone CYP3A4 DB09043|Albiglutide GLP1R common genes common pathways 17007:[DB04833 DB00239] DB04833|Methaqualone CYP3A4 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;NR1I2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;NR1I2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;NR1I2;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 17008:[DB04833 DB00666] DB04833|Methaqualone CYP3A4 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways 17009:[DB04833 DB04224] DB04833|Methaqualone CYP3A4 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes common pathways GO:0042359| vitamin D metabolic process CYP3A4;GC GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA;PPARD 17010:[DB04833 DB06719] DB04833|Methaqualone CYP3A4 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 17011:[DB04833 DB14487] DB04833|Methaqualone CYP3A4 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0006629| lipid metabolic process APOL1;CYP3A4;C3;PON1;CLU;APOE;APOA1;APOBR GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CCS;CP;ADH1C;P4HB;SOD1;CYP3A4;PRDX1;PDIA3;GAPDHS GO:0008202| steroid metabolic process APOE;APOA1;APOBR;APOL1;CYP3A4 17012:[DB04833 DB01119] DB04833|Methaqualone CYP3A4 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways 17013:[DB04833 DB05490] DB04833|Methaqualone CYP3A4 DB05490|T131 PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 17014:[DB04833 DB04552] DB04833|Methaqualone CYP3A4 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;PLA2G1B;PTGS2;CYP3A4;PTGS1;SLC16A1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1;UGT1A9 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;PTGS1 GO:0017144| drug metabolic process UGT1A9;CYP3A4 17015:[DB04833 DB11217] DB04833|Methaqualone CYP3A4 DB11217|Arbutin TYR;ALB common genes common pathways GO:0055114| oxidation-reduction process TYR;CYP3A4 17016:[DB04833 DB03541] DB04833|Methaqualone CYP3A4 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;NQO2 GO:0055114| oxidation-reduction process DHRS4L1;CYP3A4;NQO2 17017:[DB04833 DB05992] DB04833|Methaqualone CYP3A4 DB05992|Plinabulin TNF common genes common pathways 17018:[DB04833 DB04310] DB04833|Methaqualone CYP3A4 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways 17019:[DB04833 DB08479] DB04833|Methaqualone CYP3A4 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways 17020:[DB04833 DB01035] DB04833|Methaqualone CYP3A4 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6 17021:[DB04833 DB11591] DB04833|Methaqualone CYP3A4 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways 17022:[DB04833 DB05352] DB04833|Methaqualone CYP3A4 DB05352|Fx-1006A TTR common genes common pathways 17023:[DB04833 DB06775] DB04833|Methaqualone CYP3A4 DB06775|Carglumic acid CPS1 common genes common pathways 17024:[DB04833 DB05969] DB04833|Methaqualone CYP3A4 DB05969|SNS-032 CDK7;VEGFA common genes common pathways 17025:[DB04833 DB00809] DB04833|Methaqualone CYP3A4 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways 17026:[DB04833 DB02047] DB04833|Methaqualone CYP3A4 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process CYP3A4;PTGS1 17027:[DB04833 DB04879] DB04833|Methaqualone CYP3A4 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways 17028:[DB04833 DB02303] DB04833|Methaqualone CYP3A4 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP3A4 17029:[DB04833 DB00004] DB04833|Methaqualone CYP3A4 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways 17030:[DB04833 DB05461] DB04833|Methaqualone CYP3A4 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways 17031:[DB04833 DB02901] DB04833|Methaqualone CYP3A4 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP17A1;CYP3A4;CYP11A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1 GO:0006629| lipid metabolic process CYP3A4;CYP11A1;HSD17B1 GO:0055114| oxidation-reduction process CYP17A1;CYP19A1;HSD17B1;CYP11A1;CYP3A4 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 17032:[DB04833 DB00163] DB04833|Methaqualone CYP3A4 DB00163|Vitamin E NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;SEC14L4;SEC14L3;SEC14L2;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0042738| exogenous drug catabolic process NR1I2;CYP3A4 GO:0055114| oxidation-reduction process NQO1;ALOX5;CYP3A4;HMOX1;GSTO1;SOD1 GO:0006805| xenobiotic metabolic process NQO1;NR1I2;GSTP1;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;TTPA GO:0008202| steroid metabolic process NR1I2;CYP3A4 17033:[DB04833 DB06202] DB04833|Methaqualone CYP3A4 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 17034:[DB04833 DB08798] DB04833|Methaqualone CYP3A4 DB08798|Sulfamoxole CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4 17035:[DB04833 DB05905] DB04833|Methaqualone CYP3A4 DB05905|TD-2749 HTR4 common genes common pathways 17036:[DB04833 DB07477] DB04833|Methaqualone CYP3A4 DB07477|Felbinac CTSL common genes common pathways 17037:[DB04833 DB00807] DB04833|Methaqualone CYP3A4 DB00807|Proparacaine SCN10A common genes common pathways 17038:[DB04833 DB01972] DB04833|Methaqualone CYP3A4 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GMPR 17039:[DB04833 DB05662] DB04833|Methaqualone CYP3A4 DB05662|NP-50301 ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 17040:[DB04833 DB05511] DB04833|Methaqualone CYP3A4 DB05511|Piclidenoson ADORA3 common genes common pathways 17041:[DB04833 DB06879] DB04833|Methaqualone CYP3A4 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 17042:[DB04833 DB07637] DB04833|Methaqualone CYP3A4 DB07637|Dibromotyrosine EPOR common genes common pathways 17043:[DB04833 DB03158] DB04833|Methaqualone CYP3A4 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways 17044:[DB04833 DB05202] DB04833|Methaqualone CYP3A4 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways 17045:[DB04833 DB05188] DB04833|Methaqualone CYP3A4 DB05188|KD3010 PPARD common genes common pathways GO:0006629| lipid metabolic process PPARD;CYP3A4 17046:[DB04833 DB05767] DB04833|Methaqualone CYP3A4 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways 17047:[DB04833 DB06820] DB04833|Methaqualone CYP3A4 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2D6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C9 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C9 17048:[DB04833 DB00871] DB04833|Methaqualone CYP3A4 DB00871|Terbutaline ADRB2;ADRB3;ADRB1;BCHE common genes common pathways 17049:[DB04833 DB00500] DB04833|Methaqualone CYP3A4 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process PTGS2;TDO2;CYP3A4;MPO;PTGS1 17050:[DB04833 DB13869] DB04833|Methaqualone CYP3A4 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 17051:[DB04833 DB08143] DB04833|Methaqualone CYP3A4 DB08143|5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE F10 common genes common pathways 17052:[DB04833 DB00804] DB04833|Methaqualone CYP3A4 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0002933| CYP3A4;CYP1A1 17053:[DB04833 DB02820] DB04833|Methaqualone CYP3A4 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways GO:0055114| oxidation-reduction process HSD17B10;CYP3A4 GO:0006629| lipid metabolic process HSD17B10;CYP3A4 17054:[DB04833 DB00223] DB04833|Methaqualone CYP3A4 DB00223|Diflorasone NR3C1 common genes common pathways 17055:[DB04833 DB02481] DB04833|Methaqualone CYP3A4 DB02481|N-Benzylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;CYP3A4 17056:[DB04833 DB00106] DB04833|Methaqualone CYP3A4 DB00106|Abarelix GNRHR common genes common pathways 17057:[DB04833 DB00014] DB04833|Methaqualone CYP3A4 DB00014|Goserelin LHCGR;GNRHR common genes common pathways 17058:[DB04833 DB14062] DB04833|Methaqualone CYP3A4 DB14062|Concanamycin A ABCB1 common genes common pathways 17059:[DB04833 DB14514] DB04833|Methaqualone CYP3A4 DB14514|Magnesium levulinate ATP1A1 common genes common pathways 17060:[DB04833 DB04278] DB04833|Methaqualone CYP3A4 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways 17061:[DB04833 DB04787] DB04833|Methaqualone CYP3A4 DB04787|Tanaproget PGR common genes common pathways 17062:[DB04833 DB01116] DB04833|Methaqualone CYP3A4 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways 17063:[DB04833 DB09086] DB04833|Methaqualone CYP3A4 DB09086|Eugenol ESR1;ESR2;AR;TRPV3 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 17064:[DB04833 DB07675] DB04833|Methaqualone CYP3A4 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 17065:[DB04833 DB05038] DB04833|Methaqualone CYP3A4 DB05038|Anatibant BDKRB2 common genes common pathways 17066:[DB04833 DB06213] DB04833|Methaqualone CYP3A4 DB06213|Regadenoson ADORA2A common genes common pathways 17067:[DB04833 DB09327] DB04833|Methaqualone CYP3A4 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP3A4;CYP2A6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP2A6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2A6 17068:[DB04833 DB08386] DB04833|Methaqualone CYP3A4 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 17069:[DB04833 DB00891] DB04833|Methaqualone CYP3A4 DB00891|Sulfapyridine CYP2C9 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4 17070:[DB04833 DB04655] DB04833|Methaqualone CYP3A4 DB04655|Metoprine HNMT common genes common pathways 17071:[DB04833 DB08744] DB04833|Methaqualone CYP3A4 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;NQO2 GO:0055114| oxidation-reduction process CYP3A4;NQO2 17072:[DB04833 DB04253] DB04833|Methaqualone CYP3A4 DB04253|Tretazicar NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;NQO2 GO:0055114| oxidation-reduction process CYP3A4;NQO2 17073:[DB04833 DB06314] DB04833|Methaqualone CYP3A4 DB06314|SGX-523 MET common genes common pathways 17074:[DB04833 DB06246] DB04833|Methaqualone CYP3A4 DB06246|Exisulind PDE4D;PDE4C;PDE5A;PDE2A;GSTP1;AKR1B1;AKR1B10 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;GSTP1 GO:0055114| oxidation-reduction process CYP3A4;AKR1B1;AKR1B10 GO:0008202| steroid metabolic process AKR1B10;CYP3A4 17075:[DB04833 DB11811] DB04833|Methaqualone CYP3A4 DB11811|Arhalofenate PPARG common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4 17076:[DB04833 DB05259] DB04833|Methaqualone CYP3A4 DB05259|Glatiramer HLA-DRB1 common genes common pathways 17077:[DB04833 DB07385] DB04833|Methaqualone CYP3A4 DB07385|3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE NQO1 common genes common pathways GO:0006805| xenobiotic metabolic process NQO1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;NQO1 17078:[DB04833 DB11254] DB04833|Methaqualone CYP3A4 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0055114| oxidation-reduction process TYR;CYP3A4 17079:[DB04833 DB14700] DB04833|Methaqualone CYP3A4 DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0055114| oxidation-reduction process F8;CYP3A4 17080:[DB04833 DB01158] DB04833|Methaqualone CYP3A4 DB01158|Bretylium ATP1A1 common genes common pathways 17081:[DB04833 DB06752] DB04833|Methaqualone CYP3A4 DB06752|Chymopapain PRG2 common genes common pathways 17082:[DB04833 DB09095] DB04833|Methaqualone CYP3A4 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 17083:[DB04833 DB06558] DB04833|Methaqualone CYP3A4 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways 17084:[DB04833 DB13915] DB04833|Methaqualone CYP3A4 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways 17085:[DB04833 DB06623] DB04833|Methaqualone CYP3A4 DB06623|Flupirtine ADRA2A common genes common pathways 17086:[DB04833 DB00428] DB04833|Methaqualone CYP3A4 DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0002933| CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP1A1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1 17087:[DB04833 DB05793] DB04833|Methaqualone CYP3A4 DB05793|PRO-542 FFAR4 common genes common pathways 17088:[DB04833 DB00387] DB04833|Methaqualone CYP3A4 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways 17089:[DB04833 DB05133] DB04833|Methaqualone CYP3A4 DB05133|VP025 IL1B common genes common pathways 17090:[DB04833 DB03742] DB04833|Methaqualone CYP3A4 DB03742|Compound 4-D ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 17091:[DB04833 DB01278] DB04833|Methaqualone CYP3A4 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways 17092:[DB04833 DB01269] DB04833|Methaqualone CYP3A4 DB01269|Panitumumab EGFR common genes common pathways 17093:[DB04833 DB09126] DB04833|Methaqualone CYP3A4 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways 17094:[DB04833 DB05369] DB04833|Methaqualone CYP3A4 DB05369|HZT-501 HRH2 common genes common pathways 17095:[DB04833 DB01348] DB04833|Methaqualone CYP3A4 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways 17096:[DB04833 DB00961] DB04833|Methaqualone CYP3A4 DB00961|Mepivacaine SCN10A common genes common pathways 17097:[DB04833 DB04703] DB04833|Methaqualone CYP3A4 DB04703|Hesperidin AURKB common genes common pathways 17098:[DB04833 DB06825] DB04833|Methaqualone CYP3A4 DB06825|Triptorelin GNRHR common genes common pathways 17099:[DB04833 DB01941] DB04833|Methaqualone CYP3A4 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways 17100:[DB04833 DB01611] DB04833|Methaqualone CYP3A4 DB01611|Hydroxychloroquine TLR7;TLR9;CYP2D6;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A4 17101:[DB04833 DB09270] DB04833|Methaqualone CYP3A4 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways GO:0008202| steroid metabolic process LDLR;HMGCR;CYP3A4;VLDLR GO:0055114| oxidation-reduction process NDUFV3;HMGCR;SDHA;CYP3A4 GO:0006629| lipid metabolic process HMGCR;CYP3A4;VLDLR;LDLR 17102:[DB04833 DB13149] DB04833|Methaqualone CYP3A4 DB13149|Protein S human F5;F10;PROC common genes common pathways 17103:[DB04833 DB12406] DB04833|Methaqualone CYP3A4 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 17104:[DB04833 DB07393] DB04833|Methaqualone CYP3A4 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways GO:0055114| oxidation-reduction process GSR;CYP3A4 17105:[DB04833 DB01839] DB04833|Methaqualone CYP3A4 DB01839|Propylene glycol F13A1 common genes common pathways 17106:[DB04833 DB05675] DB04833|Methaqualone CYP3A4 DB05675|EP-2104R FGA common genes common pathways 17107:[DB04833 DB02262] DB04833|Methaqualone CYP3A4 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 17108:[DB04833 DB03035] DB04833|Methaqualone CYP3A4 DB03035|1,8-Di-Hydroxy-4-Nitro-Anthraquinone CSNK2A1 common genes common pathways 17109:[DB04833 DB03222] DB04833|Methaqualone CYP3A4 DB03222|dATP POLB;recA;recA common genes common pathways 17110:[DB04833 DB04776] DB04833|Methaqualone CYP3A4 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways 17111:[DB04833 DB07379] DB04833|Methaqualone CYP3A4 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways 17112:[DB04833 DB07645] DB04833|Methaqualone CYP3A4 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways 17113:[DB04833 DB04660] DB04833|Methaqualone CYP3A4 DB04660|Choline alfoscerate GM2A common genes common pathways GO:0006629| lipid metabolic process GM2A;CYP3A4 17114:[DB04833 DB00073] DB04833|Methaqualone CYP3A4 DB00073|Rituximab MS4A1 common genes common pathways 17115:[DB04833 DB06494] DB04833|Methaqualone CYP3A4 DB06494|Sufugolix GNRHR common genes common pathways 17116:[DB04833 DB07108] DB04833|Methaqualone CYP3A4 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways 17117:[DB04833 DB08642] DB04833|Methaqualone CYP3A4 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP3A4 17118:[DB04833 DB09409] DB04833|Methaqualone CYP3A4 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways 17119:[DB04833 DB00048] DB04833|Methaqualone CYP3A4 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways 17120:[DB04833 DB04581] DB04833|Methaqualone CYP3A4 DB04581|1-benzylimidazole QPCT common genes common pathways 17121:[DB04833 DB01699] DB04833|Methaqualone CYP3A4 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways 17122:[DB04833 DB06937] DB04833|Methaqualone CYP3A4 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways 17123:[DB04833 DB07800] DB04833|Methaqualone CYP3A4 DB07800|N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE F10 common genes common pathways 17124:[DB04833 DB08169] DB04833|Methaqualone CYP3A4 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 17125:[DB04833 DB06263] DB04833|Methaqualone CYP3A4 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0055114| oxidation-reduction process CBR1;CYP3A4;POR GO:0006805| xenobiotic metabolic process POR;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CBR1 17126:[DB04833 DB08709] DB04833|Methaqualone CYP3A4 DB08709|2,3-diphenyl-1H-indole-7-carboxylic acid PIM1 common genes common pathways 17127:[DB04833 DB03725] DB04833|Methaqualone CYP3A4 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways GO:0006629| lipid metabolic process PCK1;CYP3A4 17128:[DB04833 DB06809] DB04833|Methaqualone CYP3A4 DB06809|Plerixafor CXCR4 common genes common pathways 17129:[DB04833 DB02165] DB04833|Methaqualone CYP3A4 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways 17130:[DB04833 DB01082] DB04833|Methaqualone CYP3A4 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways 17131:[DB04833 DB02824] DB04833|Methaqualone CYP3A4 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways 17132:[DB04833 DB06757] DB04833|Methaqualone CYP3A4 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;IDH3A;IDH3G 17133:[DB04833 DB14526] DB04833|Methaqualone CYP3A4 DB14526|Chromic citrate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYB5A;CYP3A4 17134:[DB04833 DB01140] DB04833|Methaqualone CYP3A4 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways 17135:[DB04833 DB00121] DB04833|Methaqualone CYP3A4 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP1B1 GO:0006629| lipid metabolic process ACACA;CYP3A4;PC;ACACB GO:0055114| oxidation-reduction process CYP3A4;CYP1B1 GO:0008202| steroid metabolic process CYP3A4;CYP1B1 17136:[DB04833 DB05432] DB04833|Methaqualone CYP3A4 DB05432|DAS-431 IV CALY common genes common pathways 17137:[DB04833 DB13125] DB04833|Methaqualone CYP3A4 DB13125|Lusutrombopag MPL;CYP4A11;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP4A11;CYP3A4 17138:[DB04833 DB05389] DB04833|Methaqualone CYP3A4 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways 17139:[DB04833 DB04901] DB04833|Methaqualone CYP3A4 DB04901|Galiximab CD80 common genes common pathways 17140:[DB04833 DB06393] DB04833|Methaqualone CYP3A4 DB06393|Xaliproden HTR1A common genes common pathways 17141:[DB04833 DB12582] DB04833|Methaqualone CYP3A4 DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C9;NR1I2 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C9 GO:0008202| steroid metabolic process NR1I2;CYP2C9;CYP3A4 17142:[DB04833 DB04213] DB04833|Methaqualone CYP3A4 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP3A4 GO:0006629| lipid metabolic process EPHX2;CYP3A4 GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4 17143:[DB04833 DB07232] DB04833|Methaqualone CYP3A4 DB07232|Veliparib PARP1;PARP2 common genes common pathways 17144:[DB04833 DB05855] DB04833|Methaqualone CYP3A4 DB05855|Rivanicline CHRNB2;CXCL8 common genes common pathways 17145:[DB04833 DB13909] DB04833|Methaqualone CYP3A4 DB13909|Bismuth subgallate ALB common genes common pathways 17146:[DB04833 DB03893] DB04833|Methaqualone CYP3A4 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GAPDH 17147:[DB04833 DB08262] DB04833|Methaqualone CYP3A4 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways 17148:[DB04833 DB08745] DB04833|Methaqualone CYP3A4 DB08745|4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE F10 common genes common pathways 17149:[DB04833 DB05122] DB04833|Methaqualone CYP3A4 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways 17150:[DB04833 DB04065] DB04833|Methaqualone CYP3A4 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0017144| drug metabolic process ADH1A;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;ADH1A 17151:[DB04833 DB09075] DB04833|Methaqualone CYP3A4 DB09075|Edoxaban F10;ABCB1 common genes common pathways 17152:[DB04833 DB04720] DB04833|Methaqualone CYP3A4 DB04720|S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways 17153:[DB04833 DB08689] DB04833|Methaqualone CYP3A4 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways GO:0055114| oxidation-reduction process SDHC;CYP3A4;SDHA;SDHD;SDHB 17154:[DB04833 DB01112] DB04833|Methaqualone CYP3A4 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways 17155:[DB04833 DB05079] DB04833|Methaqualone CYP3A4 DB05079|HY10275 HRH1;HTR2A common genes common pathways 17156:[DB04833 DB05403] DB04833|Methaqualone CYP3A4 DB05403|CEP-1347 MAPK12 common genes common pathways 17157:[DB04833 DB05961] DB04833|Methaqualone CYP3A4 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways 17158:[DB04833 DB04982] DB04833|Methaqualone CYP3A4 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways 17159:[DB04833 DB11386] DB04833|Methaqualone CYP3A4 DB11386|Chlorobutanol KCNH2 common genes common pathways 17160:[DB04833 DB06021] DB04833|Methaqualone CYP3A4 DB06021|AV-412 EGFR;ERBB2 common genes common pathways 17161:[DB04833 DB04869] DB04833|Methaqualone CYP3A4 DB04869|Olcegepant CALCA;CALCRL common genes common pathways 17162:[DB04833 DB13951] DB04833|Methaqualone CYP3A4 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0006629| lipid metabolic process HSD17B1;CYP11A1;CYP3A4 GO:0055114| oxidation-reduction process CYP19A1;CYP17A1;CYP3A4;CYP11A1;HSD17B1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0008202| steroid metabolic process CYP11A1;CYP3A4;CYP17A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1 17163:[DB04833 DB09202] DB04833|Methaqualone CYP3A4 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways 17164:[DB04833 DB09161] DB04833|Methaqualone CYP3A4 DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes common pathways 17165:[DB04833 DB00141] DB04833|Methaqualone CYP3A4 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways 17166:[DB04833 DB03904] DB04833|Methaqualone CYP3A4 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways 17167:[DB04833 DB07177] DB04833|Methaqualone CYP3A4 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0055114| oxidation-reduction process PTGR1;PTGR2;CYP3A4 17168:[DB04833 DB03793] DB04833|Methaqualone CYP3A4 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process SLC16A1;CYP3A4 GO:0055114| oxidation-reduction process DAO;PRDX5;CYP3A4 17169:[DB04833 DB02925] DB04833|Methaqualone CYP3A4 DB02925|Piretanide SLC12A1 common genes common pathways 17170:[DB04833 DB08232] DB04833|Methaqualone CYP3A4 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways 17171:[DB04833 DB13501] DB04833|Methaqualone CYP3A4 DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 17172:[DB04833 DB02731] DB04833|Methaqualone CYP3A4 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways 17173:[DB04833 DB07984] DB04833|Methaqualone CYP3A4 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process PTGS1;CYP3A4 17174:[DB04833 DB06480] DB04833|Methaqualone CYP3A4 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0002933| CYP3A4 GO:0036378| CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0008202| steroid metabolic process CYP3A4 17175:[DB04833 DB04216] DB04833|Methaqualone CYP3A4 DB04216|Quercetin HCK;PIK3CG;UGT3A1;ATP5B;PIM1;HIBCH;fabZ;STK17B;ESR1;ESR2;NQO2;AHR;CYP1B1;ACTB;CSNK2A1;CSNK2B;EIF3F;HSP90AA1;HSPA2;RUVBL2;SF3B3;UBA1;SHBG;CBR1;CEBPB;NR1I2;CYP2C8;ALB;ABCC1;ABCC2;SLC16A7;SLCO2B1;ABCB1;SLC16A1;ABCG2;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SLC16A1;ATP5B GO:0006805| xenobiotic metabolic process CYP3A4;NR1I2;NQO2;AHR;CYP2C8;CYP1B1 GO:0055114| oxidation-reduction process NQO2;CYP2C8;CYP1B1;CYP3A4;CBR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C8;NR1I2 GO:0008202| steroid metabolic process CYP3A4;NR1I2;CYP2C8;CYP1B1 GO:0017144| drug metabolic process CYP2C8;CBR1;CYP3A4 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0002933| CYP3A4;CYP2C8 17176:[DB04833 DB07983] DB04833|Methaqualone CYP3A4 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;CYP3A4 17177:[DB04833 DB07769] DB04833|Methaqualone CYP3A4 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways 17178:[DB04833 DB01250] DB04833|Methaqualone CYP3A4 DB01250|Olsalazine TPMT;IFNG common genes common pathways 17179:[DB04833 DB00881] DB04833|Methaqualone CYP3A4 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways 17180:[DB04833 DB07454] DB04833|Methaqualone CYP3A4 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways 17181:[DB04833 DB00170] DB04833|Methaqualone CYP3A4 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0002933| CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP1A2;CYP2A6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6;CYP1A2;VKORC1;CYP1A1;AOX1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process XDH;MTHFR;CYP1A2;VKORC1;CYP2A6;CYP2E1;CYP3A4;VKORC1L1;NQO2;AOX1;NQO1;CYP1A1 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;NQO2;NQO1 17182:[DB04833 DB08577] DB04833|Methaqualone CYP3A4 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways 17183:[DB04833 DB05214] DB04833|Methaqualone CYP3A4 DB05214|KD7040 NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP3A4 17184:[DB04833 DB00587] DB04833|Methaqualone CYP3A4 DB00587|Cinalukast CYSLTR1 common genes common pathways 17185:[DB04833 DB05939] DB04833|Methaqualone CYP3A4 DB05939|MK-0354 GPER1 common genes common pathways 17186:[DB04833 DB00272] DB04833|Methaqualone CYP3A4 DB00272|Betazole HRH2 common genes common pathways 17187:[DB04833 DB12662] DB04833|Methaqualone CYP3A4 DB12662|Naveglitazar PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 17188:[DB04833 DB11328] DB04833|Methaqualone CYP3A4 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways 17189:[DB04833 DB09147] DB04833|Methaqualone CYP3A4 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways 17190:[DB04833 DB00109] DB04833|Methaqualone CYP3A4 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2E1 17191:[DB04833 DB02371] DB04833|Methaqualone CYP3A4 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways 17192:[DB04833 DB02028] DB04833|Methaqualone CYP3A4 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways 17193:[DB04833 DB07209] DB04833|Methaqualone CYP3A4 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 17194:[DB04833 DB08583] DB04833|Methaqualone CYP3A4 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways 17195:[DB04833 DB00222] DB04833|Methaqualone CYP3A4 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4 17196:[DB04833 DB00721] DB04833|Methaqualone CYP3A4 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP3A4;MAOB 17197:[DB04833 DB14507] DB04833|Methaqualone CYP3A4 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways 17198:[DB04833 DB01195] DB04833|Methaqualone CYP3A4 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0070989| oxidative demethylation CYP3A4;CYP2C9;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP2C9;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP3A4 17199:[DB04833 DB11071] DB04833|Methaqualone CYP3A4 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 17200:[DB04833 DB08191] DB04833|Methaqualone CYP3A4 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways 17201:[DB04833 DB13257] DB04833|Methaqualone CYP3A4 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes common pathways GO:0055114| oxidation-reduction process NOS2;NDUFS8;SUOX;P4HA1;RRM1;TPH1;TMLHE;CYP3A4;SDHA;PTGS2;CYP4A11;XDH;CAT;PCBD1;FTH1;PTGS1;CP;MPO GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 17202:[DB04833 DB00056] DB04833|Methaqualone CYP3A4 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 17203:[DB04833 DB08478] DB04833|Methaqualone CYP3A4 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways 17204:[DB04833 DB07931] DB04833|Methaqualone CYP3A4 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0008202| steroid metabolic process NR1I2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;NR1I2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0055114| oxidation-reduction process CYP3A4;AKR1C1 GO:0006805| xenobiotic metabolic process CYP3A4;AKR1C1;NR1I2 17205:[DB04833 DB07112] DB04833|Methaqualone CYP3A4 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways GO:0055114| oxidation-reduction process EGLN1;CYP3A4 17206:[DB04833 DB01827] DB04833|Methaqualone CYP3A4 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways 17207:[DB04833 DB11219] DB04833|Methaqualone CYP3A4 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 17208:[DB04833 DB03732] DB04833|Methaqualone CYP3A4 DB03732|Etheno-Nadp BST1 common genes common pathways 17209:[DB04833 DB03382] DB04833|Methaqualone CYP3A4 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1 17210:[DB04833 DB06637] DB04833|Methaqualone CYP3A4 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 17211:[DB04833 DB08790] DB04833|Methaqualone CYP3A4 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways GO:0006629| lipid metabolic process CYP3A4;HPGDS 17212:[DB04833 DB03935] DB04833|Methaqualone CYP3A4 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways 17213:[DB04833 DB00027] DB04833|Methaqualone CYP3A4 DB00027|Gramicidin D ABCB1 common genes common pathways 17214:[DB04833 DB00722] DB04833|Methaqualone CYP3A4 DB00722|Lisinopril ACE common genes common pathways 17215:[DB04833 DB01746] DB04833|Methaqualone CYP3A4 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways 17216:[DB04833 DB09031] DB04833|Methaqualone CYP3A4 DB09031|Miltefosine ABCB1;PLD1 common genes common pathways GO:0006629| lipid metabolic process PLD1;CYP3A4 17217:[DB04833 DB08429] DB04833|Methaqualone CYP3A4 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways 17218:[DB04833 DB02217] DB04833|Methaqualone CYP3A4 DB02217|Dpb-T NT5M common genes common pathways 17219:[DB04833 DB09552] DB04833|Methaqualone CYP3A4 DB09552|Thonzonium ATP6V1C1 common genes common pathways 17220:[DB04833 DB03480] DB04833|Methaqualone CYP3A4 DB03480|Brequinar Analog DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP3A4 17221:[DB04833 DB04531] DB04833|Methaqualone CYP3A4 DB04531|Benzylcysteine MGMT common genes common pathways 17222:[DB04833 DB01625] DB04833|Methaqualone CYP3A4 DB01625|Isopropamide CHRM3;CHRM4 common genes common pathways 17223:[DB04833 DB05035] DB04833|Methaqualone CYP3A4 DB05035|Eprotirome THRA;THRB common genes common pathways 17224:[DB04833 DB00672] DB04833|Methaqualone CYP3A4 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19 GO:0042737| drug catabolic process CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C9;PTGS1;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PTGS1;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;PTGS1;CYP3A4 17225:[DB04833 DB06729] DB04833|Methaqualone CYP3A4 DB06729|Sulfaphenazole CYP2C9;CYP2B6;CYP2C8;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2D6;CYP2C8;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C9;CYP2B6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2D6;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP2B6;CYP2C9;CYP3A4 GO:0002933| CYP3A4;CYP2C8 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2D6;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2D6;CYP2C8;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP2C8;CYP2D6;CYP2C9 17226:[DB04833 DB11079] DB04833|Methaqualone CYP3A4 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A4;PTGS1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;PTGS1 17227:[DB04833 DB02300] DB04833|Methaqualone CYP3A4 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;MPO;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP24A1 17228:[DB04833 DB08437] DB04833|Methaqualone CYP3A4 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways 17229:[DB04833 DB08313] DB04833|Methaqualone CYP3A4 DB08313|nocodazole HPGDS common genes common pathways GO:0006629| lipid metabolic process HPGDS;CYP3A4 17230:[DB04833 DB04752] DB04833|Methaqualone CYP3A4 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways 17231:[DB04833 DB12747] DB04833|Methaqualone CYP3A4 DB12747|Tertomotide TERT common genes common pathways 17232:[DB04833 DB13170] DB04833|Methaqualone CYP3A4 DB13170|Plecanatide GUCY1A2 common genes common pathways 17233:[DB04833 DB01073] DB04833|Methaqualone CYP3A4 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;RRM1 17234:[DB04833 DB00436] DB04833|Methaqualone CYP3A4 DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways 17235:[DB04833 DB03983] DB04833|Methaqualone CYP3A4 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways GO:0055114| oxidation-reduction process SUOX;CYP3A4 17236:[DB04833 DB00092] DB04833|Methaqualone CYP3A4 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways 17237:[DB04833 DB07974] DB04833|Methaqualone CYP3A4 DB07974|1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE F10 common genes common pathways 17238:[DB04833 DB13983] DB04833|Methaqualone CYP3A4 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways 17239:[DB04833 DB08383] DB04833|Methaqualone CYP3A4 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways 17240:[DB04833 DB02895] DB04833|Methaqualone CYP3A4 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;GSR 17241:[DB04833 DB06766] DB04833|Methaqualone CYP3A4 DB06766|Alcaftadine HRH1 common genes common pathways 17242:[DB04833 DB02967] DB04833|Methaqualone CYP3A4 DB02967|N-Ethylmaleimide CLC common genes common pathways 17243:[DB04833 DB05207] DB04833|Methaqualone CYP3A4 DB05207|SD118 TNF;IL1R1 common genes common pathways 17244:[DB04833 DB06677] DB04833|Methaqualone CYP3A4 DB06677|Clazosentan EDNRA common genes common pathways 17245:[DB04833 DB04258] DB04833|Methaqualone CYP3A4 DB04258|Seocalcitol VDR common genes common pathways 17246:[DB04833 DB01188] DB04833|Methaqualone CYP3A4 DB01188|Ciclopirox ATP1A1 common genes common pathways 17247:[DB04833 DB11221] DB04833|Methaqualone CYP3A4 DB11221|Dioxybenzone SHBG common genes common pathways 17248:[DB04833 DB06548] DB04833|Methaqualone CYP3A4 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 17249:[DB04833 DB11098] DB04833|Methaqualone CYP3A4 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways 17250:[DB04833 DB00045] DB04833|Methaqualone CYP3A4 DB00045|Lyme disease vaccine (recombinant OspA) TLR2 common genes common pathways 17251:[DB04833 DB04372] DB04833|Methaqualone CYP3A4 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 17252:[DB04833 DB00905] DB04833|Methaqualone CYP3A4 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;AKR1C3 GO:0055114| oxidation-reduction process CYP3A4;AKR1C3 17253:[DB04833 DB00466] DB04833|Methaqualone CYP3A4 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0002933| CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A1 17254:[DB04833 DB01078] DB04833|Methaqualone CYP3A4 DB01078|Deslanoside ATP1A1 common genes common pathways 17255:[DB04833 DB09139] DB04833|Methaqualone CYP3A4 DB09139|Technetium Tc-99m oxidronate ALB common genes common pathways 17256:[DB04833 DB11945] DB04833|Methaqualone CYP3A4 DB11945|Avelumab CD274 common genes common pathways 17257:[DB04833 DB01786] DB04833|Methaqualone CYP3A4 DB01786|D-Alanine SLC16A10 common genes common pathways 17258:[DB04833 DB04451] DB04833|Methaqualone CYP3A4 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways 17259:[DB04833 DB01225] DB04833|Methaqualone CYP3A4 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;CYP3A4 17260:[DB04833 DB06258] DB04833|Methaqualone CYP3A4 DB06258|Bimoclomol HSF1 common genes common pathways 17261:[DB04833 DB01260] DB04833|Methaqualone CYP3A4 DB01260|Desonide NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4 GO:0017144| drug metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4 GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4 17262:[DB04833 DB05624] DB04833|Methaqualone CYP3A4 DB05624|Teverelix GNRHR common genes common pathways 17263:[DB04833 DB04020] DB04833|Methaqualone CYP3A4 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways 17264:[DB04833 DB05119] DB04833|Methaqualone CYP3A4 DB05119|Rilapladib PLA2G7 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G7 17265:[DB04833 DB11770] DB04833|Methaqualone CYP3A4 DB11770|Talinolol CYP2D6 common genes common pathways GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP2D6 17266:[DB04833 DB07723] DB04833|Methaqualone CYP3A4 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PPARG 17267:[DB04833 DB08038] DB04833|Methaqualone CYP3A4 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 17268:[DB04833 DB04711] DB04833|Methaqualone CYP3A4 DB04711|Iodipamide ALB common genes common pathways 17269:[DB04833 DB03510] DB04833|Methaqualone CYP3A4 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways 17270:[DB04833 DB04830] DB04833|Methaqualone CYP3A4 DB04830|Buformin SLC22A1 common genes common pathways 17271:[DB04833 DB06681] DB04833|Methaqualone CYP3A4 DB06681|Belatacept CD86;CD80 common genes common pathways 17272:[DB04833 DB04664] DB04833|Methaqualone CYP3A4 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2B6 GO:0055114| oxidation-reduction process CYP2B6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2B6 17273:[DB04833 DB08480] DB04833|Methaqualone CYP3A4 DB08480|4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;MAOB 17274:[DB04833 DB06897] DB04833|Methaqualone CYP3A4 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways 17275:[DB04833 DB05150] DB04833|Methaqualone CYP3A4 DB05150|CAD106 APP common genes common pathways 17276:[DB04833 DB01381] DB04833|Methaqualone CYP3A4 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PLA2G2A GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4 17277:[DB04833 DB01208] DB04833|Methaqualone CYP3A4 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A4;CYP1A2 17278:[DB04833 DB04287] DB04833|Methaqualone CYP3A4 DB04287|(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PLA2G2A 17279:[DB04833 DB01283] DB04833|Methaqualone CYP3A4 DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9 GO:0017144| drug metabolic process UGT1A9;CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;UGT1A9;CYP2C19;CYP3A4;CYP1A2;PTGS1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP3A4;PTGS1;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;PTGS1;CYP1A2;PTGS2;CYP3A4 17280:[DB04833 DB08354] DB04833|Methaqualone CYP3A4 DB08354|2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 17281:[DB04833 DB04150] DB04833|Methaqualone CYP3A4 DB04150|Threonine Derivative PAM common genes common pathways GO:0055114| oxidation-reduction process PAM;CYP3A4 17282:[DB04833 DB04716] DB04833|Methaqualone CYP3A4 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways 17283:[DB04833 DB06835] DB04833|Methaqualone CYP3A4 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 17284:[DB04833 DB01003] DB04833|Methaqualone CYP3A4 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways 17285:[DB04833 DB05311] DB04833|Methaqualone CYP3A4 DB05311|Ecallantide KLKB1 common genes common pathways 17286:[DB04833 DB11597] DB04833|Methaqualone CYP3A4 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 17287:[DB04833 DB07033] DB04833|Methaqualone CYP3A4 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways 17288:[DB04833 DB00022] DB04833|Methaqualone CYP3A4 DB00022|Peginterferon alfa-2b IFNAR1;IFNAR2;CYP1A2;CYP2D6;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0042738| exogenous drug catabolic process CYP2C9;CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP1A2;CYP3A4 17289:[DB04833 DB03408] DB04833|Methaqualone CYP3A4 DB03408|gamma-Glutamylcysteine GSS common genes common pathways 17290:[DB04833 DB01830] DB04833|Methaqualone CYP3A4 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways 17291:[DB04833 DB08933] DB04833|Methaqualone CYP3A4 DB08933|Luliconazole CYP3A4;CYP2C19 common genes CYP3A4 common pathways GO:0006706| steroid catabolic process CYP3A4 GO:0006629| lipid metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4 GO:0042737| drug catabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP3A4 GO:0070989| oxidative demethylation CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4 17292:[DB04833 DB05465] DB04833|Methaqualone CYP3A4 DB05465|Tandutinib FLT3;PDGFD common genes common pathways 17293:[DB04833 DB11632] DB04833|Methaqualone CYP3A4 DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A4 GO:0002933| CYP2C8;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2C19;CYP2C8 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;CYP2C19 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2C19;CYP2C8 17294:[DB04833 DB02676] DB04833|Methaqualone CYP3A4 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways 17295:[DB04833 DB02555] DB04833|Methaqualone CYP3A4 DB02555|SP4160 IL2 common genes common pathways 17296:[DB04833 DB08891] DB04833|Methaqualone CYP3A4 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways 17297:[DB04833 DB01884] DB04833|Methaqualone CYP3A4 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways 17298:[DB04833 DB04677] DB04833|Methaqualone CYP3A4 DB04677|N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOB;CYP3A4 17299:[DB04833 DB01060] DB04833|Methaqualone CYP3A4 DB01060|Amoxicillin CYP2C19;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C19;CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP3A4 17300:[DB04833 DB06160] DB04833|Methaqualone CYP3A4 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4 17301:[DB04833 DB04079] DB04833|Methaqualone CYP3A4 DB04079|Heptane-1,2,3-Triol RHO common genes common pathways 17302:[DB04833 DB03881] DB04833|Methaqualone CYP3A4 DB03881|MT-Immucillin-H PNP common genes common pathways 17303:[DB04833 DB01276] DB04833|Methaqualone CYP3A4 DB01276|Exenatide GLP1R;ALB common genes common pathways 17304:[DB04833 DB14040] DB04833|Methaqualone CYP3A4 DB14040|Eptinezumab CALCA;CALCB common genes common pathways 17305:[DB04833 DB01949] DB04833|Methaqualone CYP3A4 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 17306:[DB04833 DB05217] DB04833|Methaqualone CYP3A4 DB05217|GMX1777 NAMPT common genes common pathways 17307:[DB14011 DB07543] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;ADRB2;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ADRB2 GO:0002024| diet induced thermogenesis ADRB2;TRPV4;TRPV1 GO:0045453| bone resorption ADRB2;GPR55 GO:0007165| signal transduction CHRNA7;ADRB2;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB2;CNR1 GO:0009409| response to cold TRPM8;TRPA1;PPARG;ADRB2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;ADRB2 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 17308:[DB14011 DB00504] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00504|Levallorphan OPRM1 common genes OPRM1 common pathways GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;TRPV1;TRPA1 GO:0045471| response to ethanol SOD1;CNR1;OPRM1;HMGCR;CAT GO:0007600| sensory perception TRPV2;OPRM1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;HTR2A;GLRA3;OPRM1;OPRD1 GO:0070588| calcium ion transmembrane transport CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3 GO:0044849| OPRM1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4 GO:0071315| cellular response to morphine OPRM1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1 GO:0042755| eating behavior OPRM1;OPRD1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007626| locomotory behavior OPRM1;SOD1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRM1;OPRD1;GLRB;GLRA1 GO:0070848| response to growth factor stimulus OPRM1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;OPRM1;CYP1A2;PTGS2;CNR2 GO:0033554| cellular response to stress OPRM1 GO:0042060| wound healing OPRM1;ALOX15 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1 GO:0043278| response to morphine CNR1;OPRM1 GO:0032100| positive regulation of appetite OPRM1 GO:0032094| response to food CYP1A1;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PPARG;GPR18 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;CNR2;OPRD1;CNR1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1 GO:0042220| response to cocaine SMPD1;CNR1;OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 17309:[DB14011 DB00413] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes HTR2A;HTR1A common pathways GO:0048148| behavioral response to cocaine DRD1;HTR2A;DRD4;DRD2;DRD3 GO:0042428| serotonin metabolic process HTR1A GO:0035556| intracellular signal transduction PLA2G1B;DRD2 GO:0042310| vasoconstriction HTR2B;HTR1B;HTR1A;HTR1D GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A;HTR2C GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0001659| temperature homeostasis TRPV1;DRD2;HTR2A;GPX1;DRD1 GO:0071312| cellular response to alkaloid HTR1B;TRPV1 GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0007507| heart development PPARG;HTR2B GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0048678| response to axon injury DRD2;SOD1 GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;TRPV1;TRPA1 GO:0030431| sleep CACNA1I;SLC29A1;HTR2A GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;DRD1;CACNA1H GO:0045821| positive regulation of glycolysis HTR2A GO:0045471| response to ethanol DRD2;HTR1B;DRD3;CAT;SOD1;CNR1;OPRM1;HMGCR GO:0045776| negative regulation of blood pressure DRD5;CNR1;DRD2;DRD3 GO:0016032| viral reproduction HTR2A;VDAC1 GO:0001964| startle response GLRA1;GLRB;DRD2 GO:0019226| transmission of nerve impulse SOD1;DRD1;DRD5 GO:0008542| visual learning DRD2;DRD3;DRD1;HMGCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0033674| positive regulation of kinase activity DRD4;HTR2A GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0048149| behavioral response to ethanol DRD4;OPRM1;DRD2 GO:0007268| synaptic transmission GLRA1;CACNA1G;HTR2C;VDAC1;HTR1B;GLRB;HTR2A;GLRA3;OPRD1;HTR1D;OPRM1;DRD5 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;TRPA1 GO:0007565| female pregnancy IDO1;ADRA2B;ADRA2C GO:0045907| positive regulation of vasoconstriction ADRA2C;HTR2A;PTGS2 GO:0001819| positive regulation of cytokine production ADRA2A;HTR2B;SOD1 GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0050482| arachidonic acid secretion DRD3;DRD2;PLA2G1B;DRD4 GO:1900273| DRD2;CHRNA7 GO:0006939| smooth muscle contraction HTR2B;HTR1D;HTR2A GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;HTR2B GO:0007165| signal transduction DRD3;GPR18;PPARG;SMPD1;ADRA2A;HTR2C;HTR2B;DRD2;CACNA1I;HTR1B;PLA2G1B;ADRA2B;CNR1;GPR12;HTR2A;ADRA2C;GPR55;DRD4;HTR1A;HTR1D;OPRD1;CNR2;OPRM1;DRD1;CHRNA7;DRD5 GO:0007610| behavior HTR2B;HTR2C;HTR1B;HTR1A;HTR2A GO:0001975| response to amphetamine DRD2;DRD3;DRD5;DRD1;CNR2;DRD4;SOD1 GO:0046718| entry of virus into host cell HTR2A GO:0040014| regulation of multicellular organism growth SOD1;DRD3 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;DRD3;CNR1;HMGCR GO:0072593| reactive oxygen species metabolic process SOD1;DRD5 GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;HTR1B;OPRM1;OPRD1;HTR1D GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1 GO:0050796| regulation of insulin secretion ADRA2C;CNR1;ADRA2A GO:0007613| memory PTGS2;CNR1;HTR2A;DRD1;CHRNA7 GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0042053| regulation of dopamine metabolic process HTR1A;DRD4;DRD1 GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0051781| positive regulation of cell division CAT;HTR2B GO:0008285| negative regulation of cell proliferation CYP1B1;DRD2;PPARG;OPRM1;PTGS2 GO:0046883| regulation of hormone secretion HTR1A;HTR2A GO:0001662| behavioral fear response DRD4;HTR1A;DRD1;VDAC1;HTR2C GO:0006812| cation transport SLC22A2;TRPM8;SLC22A1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A;HTR1B GO:0043267| negative regulation of potassium ion transport HTR2A GO:0009636| response to toxin HTR1D;GPX1;CAT;CYP1A1;DRD2;CYP1B1 GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0032229| negative regulation of synaptic transmission, GABAergic HTR1B;CNR2 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;SLC22A2;TRPM8;CACNA1G;SLC22A1;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADRA2C GO:0045777| positive regulation of blood pressure CNR1;ADRA2B GO:0008344| adult locomotory behavior OPRD1;DRD4 GO:0006855| drug transmembrane transport ABCC1;SLC22A1;SLC22A2;ABCG2 GO:0014854| response to inactivity DRD2;CAT GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;HTR2B GO:0042311| vasodilation DRD1;GPX1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD5;DRD1;DRD3 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;ADRA2A;HTR2B;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;DRD3;PLA2G1B;DRD2 GO:0007626| locomotory behavior DRD3;HTR2C;DRD2;SOD1;OPRM1;DRD1 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0050795| regulation of behavior HTR1D;HTR1A;HTR2A;HTR1B;HTR2B GO:0007628| adult walking behavior DRD1;GLRB;DRD2;GLRA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;PPARG;TRPV4;TRPV1 GO:0007611| learning or memory DRD3;CNR1;CHRNA7 GO:0042060| wound healing OPRM1;DRD5;ALOX15 GO:0007612| learning PTGS2;DRD1;DRD5;DRD3;VDAC1 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0014824| artery smooth muscle contraction HTR2A GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;TRPV1;DRD2;GLRB;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2C;HTR2B;OPRD1;OPRM1;HTR2A GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2A;HTR2B;HTR2C GO:0035094| response to nicotine CHRNA7;CNR1;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR1B;DRD2;HTR2A GO:0043278| response to morphine DRD3;DRD2;OPRM1;CNR1 GO:0035640| exploration behavior HTR1A GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;DRD1;SMPD1;ABCC1;PPARG;CYP1A1;DRD3;TRPA1;HTR1B;DRD2;HTR2B;HTR2C;ABCG2 GO:0044380| protein localization to cytoskeleton HTR2A GO:0007210| serotonin receptor signaling pathway HTR2B;HTR2C;HTR1A;HTR2A GO:0006936| muscle contraction GLRA1;DRD1;CACNA1H GO:0006874| cellular calcium ion homeostasis TRPM8;HTR2B;HTR2C;TRPV4;DRD2;DRD3;CHRNA7;DRD5;HTR2A;GPR12;DRD4 GO:0042593| glucose homeostasis PPARG;ADRA2A;TRPV4;CNR1 GO:0051260| protein homooligomerization SLC22A1;GLRA1;GLRA3;ACAT1 GO:0007186| G-protein coupled receptor signaling pathway DRD5;DRD1;OPRM1;CNR2;OPRD1;HTR1D;HTR1A;GPR55;DRD4;ADRA2C;CNR1;GPR12;HTR2A;ADRA2B;HTR1B;DRD2;HTR2C;HTR2B;ADRA2A;PPARG;GPR18;DRD3 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;HTR2B;HTR2C;DRD2;TRPV1 GO:0007568| aging CAT;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0010628| positive regulation of gene expression DRD1;TRPV4 GO:0007202| activation of phospholipase C activity HTR2B;HTR2A;GPR55 GO:0001666| response to hypoxia DRD2;CYP1A1;CAT;CHRNA7 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;DRD4 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;HTR2C;DRD2;GPR55;DRD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0014059| regulation of dopamine secretion DRD3;DRD2;HTR1B;HTR2A GO:0009416| response to light stimulus AANAT;DRD2 GO:0048511| rhythmic process AANAT;DRD4;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;ADRA2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR1B;CNR1;OPRD1;HTR1D;OPRM1;CNR2;DRD1 GO:0014062| regulation of serotonin secretion HTR1A GO:0071502| cellular response to temperature stimulus TRPV1;HTR1B;HTR2B GO:0008219| cell death HTR2A GO:0042220| response to cocaine DRD1;DRD5;CNR1;OPRM1;DRD2;HTR1B;DRD3;SMPD1 GO:0000187| activation of MAPK activity PLA2G1B;DRD4;SOD1;ADRA2B;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;HTR2C;HTR2B;ALOX15;DRD2;TRPV4 GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;SLC22A2;TRPM8;CACNA1G;ABCC1;SLC22A1;TRPA1;TRPV2;CACNA1H;TRPV3 17310:[DB14011 DB03685] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;B4GALT1;PPARG GO:0008152| metabolic process SMPD1;UCKL1;ACAT1 GO:0016032| viral reproduction VDAC1;UCKL1;HTR2A GO:0060055| angiogenesis involved in wound healing B4GALT1;GPX1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;ISG20 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;B4GALT1 GO:0042127| regulation of cell proliferation B4GALT1;PTGS1;PTGS2 GO:0042060| wound healing ALOX15;B4GALT1;OPRM1 GO:0045087| innate immune response PPARG;ISG20 GO:0007155| cell adhesion B4GALT1;CYP1B1 GO:0043312| neutrophil degranulation ALOX5;CAT;B4GALT1 GO:0009615| response to virus CYP1A1;ISG20 GO:0051260| protein homooligomerization GLRA1;B4GALT1;ACAT1;GLRA3 GO:0002376| immune system process IDO1;ISG20 17311:[DB14011 DB07926] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07926|N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE MMP1 common genes common pathways GO:0016032| viral reproduction HTR2A;MMP1;VDAC1 17312:[DB14011 DB07218] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07218|6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE MAPK8IP1;MAPK8 common genes common pathways GO:0071276| cellular response to cadmium ion MAPK8;CYP1A2;SOD1 GO:0009411| response to UV CAT;MAPK8 GO:0007165| signal transduction PPARG;GPR18;SMPD1;MAPK8IP1;PLA2G1B;CACNA1I;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0042752| regulation of circadian rhythm PPARG;MAPK8 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;MAPK8;CNR1;SOD1;PTGS2 GO:0071260| cellular response to mechanical stimulus MAPK8;PTGS2 GO:0010628| positive regulation of gene expression MAPK8;TRPV4 GO:0048511| rhythmic process AANAT;MAPK8;PPARG GO:0051247| positive regulation of protein metabolic process CHRNA7;MAPK8 GO:0006355| regulation of transcription, DNA-dependent PPARG;MAPK8IP1 GO:0043066| negative regulation of apoptotic process MAPK8;GPX1;CAT;HMGCR;PTGS2;SOD1;MAPK8IP1 17313:[DB14011 DB01179] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0043065| positive regulation of apoptotic process PPARG;TOP2A;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0002576| platelet degranulation SOD1;TUBA4A GO:0043312| neutrophil degranulation CAT;ALOX5;TUBB GO:0048511| rhythmic process TOP2A;PPARG;AANAT 17314:[DB14011 DB05127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05127|ANA971 TLR7 common genes common pathways GO:0002376| immune system process IDO1;TLR7 GO:0045087| innate immune response PPARG;TLR7 GO:0007165| signal transduction TLR7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 GO:0050729| positive regulation of inflammatory response TLR7;TRPV4 GO:0006955| immune response TLR7;OPRD1;CNR2 GO:0006954| inflammatory response TLR7;ALOX15;IDO1;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR7 GO:0001774| microglial cell activation TRPV1;TLR7 17315:[DB14011 DB03372] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways GO:0002376| immune system process IDO1;IL2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;IL2;GPR18;PPARG GO:0050728| negative regulation of inflammatory response IL2;CNR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;IL2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;IL2 GO:0043066| negative regulation of apoptotic process IL2;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0007155| cell adhesion CYP1B1;IL2 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0050729| positive regulation of inflammatory response TRPV4;IL2 GO:0007204| elevation of cytosolic calcium ion concentration IL2;TRPV4;TRPV1;HTR2A;OPRM1 GO:0030217| T cell differentiation IL2;GPR18 GO:0006955| immune response CNR2;OPRD1;IL2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;IL2 GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CAT;IL2 17316:[DB14011 DB02059] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02059|Adenosine-5-Diphosphoribose EEF2;GAPDH;SIRT5;SIRT3 common genes common pathways GO:0034976| response to endoplasmic reticulum stress EEF2;ALOX15 GO:0061844| GAPDH;PLA2G1B GO:2000378| negative regulation of reactive oxygen species metabolic process SIRT3;VDAC1;SIRT5 GO:0031667| response to nutrient levels SIRT5;SOD1 GO:0042542| response to hydrogen peroxide TRPA1;EEF2;GPX1;CAT;SOD1 GO:0045471| response to ethanol EEF2;CAT;HMGCR;OPRM1;SOD1;CNR1 GO:0006915| apoptotic process GAPDH;GPX1;VDAC1 GO:0009060| aerobic respiration SIRT3;CAT GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;EEF2 GO:0007568| aging SIRT3;CYP1A1;CAT;EEF2;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2 GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;EEF2;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0055114| oxidation-reduction process SOD1;GAPDH;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP1A1;CYP2C9;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0043312| neutrophil degranulation CAT;EEF2;ALOX5 17317:[DB14011 DB09213] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09213|Dexibuprofen PTGS2;PTGS1;BCL2;THBD;PLAT;FABP2;PPARG;CFTR;SLC15A1;PPARA;GP1BA;S100A7;CYP2C9;UGT1A1;UGT1A3;UGT1A9;UGT2B4;UGT2B7;CYP2C8;CYP2C19;AMACR;ALB;ABCC4;ABCC1;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLCO2B1;ABCB1 common genes PPARG;CYP2C9;PTGS1;CYP2C19;PTGS2;ABCC1 common pathways GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0043524| negative regulation of neuron apoptosis BCL2;SOD1 GO:0071320| cellular response to cAMP AANAT;CFTR GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0008631| induction of apoptosis by oxidative stress CYP1B1;BCL2;GPX1 GO:1901558| PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0061614| PPARG GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0007565| female pregnancy IDO1;BCL2;THBD GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0030217| T cell differentiation BCL2;GPR18 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS2;CNR2;ALOX5;PTGS1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0043603| cellular amide metabolic process CYP2C9 GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:1902476| GLRB;CFTR;GLRA1;GLRA3 GO:0051924| regulation of calcium ion transport OPRD1;BCL2 GO:0050872| white fat cell differentiation PPARG GO:0071498| cellular response to fluid shear stress PTGS2 GO:1904706| PPARG GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0045471| response to ethanol UGT1A1;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0001525| angiogenesis S100A7;CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;GP1BA GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0019233| sensory perception of pain HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1;TRPV1;TRPA1 GO:0001889| liver development ACAT1;UGT1A1;CYP1A1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation CAT;BCL2;OPRM1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;CAT;BCL2;SOD1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C8;CYP2C19;CYP2D6;CYP3A5;UGT1A9;CYP2C9;UGT2B4;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:1990776| PTGS2 GO:0008152| metabolic process UGT2B7;UGT1A3;ACAT1;UGT1A9;UGT1A1;SMPD1;UGT2B4 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0001503| ossification ALOX15;BCL2 GO:0007507| heart development PPARG;PPARA GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0006629| lipid metabolic process UGT2B7;GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;PPARA;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0034775| glutathione transmembrane transport ABCC1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0042953| lipoprotein transport PPARG GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;BCL2 GO:0006811| ion transport SLC15A1;GLRA1;TRPA1;CACNA1G;CFTR;SLCO2B1;TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;GLRA3;SLC22A8;TRPV3;SLCO1A2;CACNA1H;CHRNA7;SLC22A11;TRPV2 GO:0033280| response to vitamin D PTGS2 GO:0008283| cell proliferation CYP1A1;BCL2;HTR1A;GPX1 GO:0019627| urea metabolic process CYP2C9 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;UGT1A1;AANAT;ACAT1;ABCC4;CYP1A2;PTGS2 GO:0009636| response to toxin CYP1A1;CYP1B1;BCL2;SLC22A8;GPX1;CAT GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0032868| response to insulin stimulus PPARA;AANAT;CAT;TRPV4 GO:0051881| regulation of mitochondrial membrane potential OPRD1;BCL2;SOD1 GO:0001895| retina homeostasis ALB;SOD1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0030336| negative regulation of cell migration BCL2;CYP1B1 GO:0009791| post-embryonic development BCL2;CYP1A2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0055088| lipid homeostasis PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0043627| response to estrogen stimulus PPARG GO:0001662| behavioral fear response BCL2;HTR1A;VDAC1 GO:0061844| PLA2G1B;S100A7 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;UGT1A1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCL2;CYP1B1;PPARG GO:0098656| SLC22A8;SLC22A6;VDAC1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2;PTGS2 GO:0072593| reactive oxygen species metabolic process BCL2;SOD1 GO:0015889| cobalamin transport ABCC1 GO:1905461| PPARG GO:0010226| response to lithium ion PTGS2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0019216| regulation of lipid metabolic process UGT1A9;CYP1A1;PPARG;HMGCR;CNR1;PPARA GO:0099039| ABCC1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0006821| chloride transport GLRA1;CFTR;GLRB;GLRA3 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;THBD;HTR1A;GPR55;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0097267| CYP1A2;CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0034644| cellular response to UV PTGS2 GO:0010332| response to gamma radiation BCL2;GPX1 GO:0070542| response to fatty acid CAT;PTGS2 GO:0042493| response to drug ABCG2;ABCB1;PPARG;CYP1A1;TRPA1;UGT1A1;ABCC1;SMPD1;CAT;ABCC4;SOD1;HTR2A;PTGS2;CYP1A2;BCL2 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA GO:0006631| fatty acid metabolic process ALOX15;AMACR;PTGS1;PPARA;PTGS2 GO:0099133| ABCC4;CFTR;ABCC1 GO:0030224| monocyte differentiation PPARG GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process ABCC4;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C8;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9 GO:0007569| cell aging BCL2;SOD1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071455| cellular response to hyperoxia PPARG GO:0010243| response to organic nitrogen ABCC4;PTGS2;TRPV1 GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2;HMGCR GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0007015| actin filament organization PLA2G1B;TRPV4;BCL2 GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0009750| response to fructose stimulus PTGS2 GO:0060326| cell chemotaxis ABCC1 GO:0035094| response to nicotine BCL2;CNR1;CHRNA7 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0042060| wound healing OPRM1;PPARA;ALOX15 GO:0007612| learning PTGS2;VDAC1 GO:0000302| response to reactive oxygen species S100A7;GPX1;CAT;SOD1 GO:0032496| response to lipopolysaccharide CNR1;THBD;OPRM1;CYP1A2;CNR2;PTGS2;IDO1;S100A7;CYP1A1;UGT1A1 GO:0030308| negative regulation of cell growth PPARG;BCL2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0032526| response to retinoic acid PPARG GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0006695| cholesterol biosynthetic process HMGCR;CFTR GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0071284| cellular response to lead ion PTGS2 GO:0002576| platelet degranulation SOD1;ABCC4;ALB GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;BCL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PPARA GO:0001822| kidney development BCL2;CAT GO:0071300| cellular response to retinoic acid PPARG GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP2C8;CYP1B1;CYP2C9;CYP1A1 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;BCL2;HMGCR;PTGS2 GO:0007155| cell adhesion GP1BA;CYP1B1 GO:0045087| innate immune response PPARG;S100A7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TRPV1;TRPV4 GO:0034097| response to cytokine stimulus PTGS2;BCL2;AANAT GO:0042594| response to starvation UGT1A1;PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0043312| neutrophil degranulation ALOX5;CAT;S100A7 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP2C8;CYP3A5 GO:0051591| response to cAMP THBD;AANAT GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;S100A7;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0055085| transmembrane transport TRPV2;ABCC4;SLC22A11;CACNA1H;BCL2;SLCO1A2;TRPV3;SLC22A8;TRPV1;VDAC1;ABCB1;TRPV4;CACNA1I;ABCG2;SLCO2B1;TRPM8;SLC22A6;CACNA1G;CFTR;ABCC1;SLC15A1;TRPA1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0006915| apoptotic process BCL2;GPX1;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0001541| ovarian follicle development SOD1;BCL2 GO:0001657| ureteric bud development BCL2;CAT GO:0001666| response to hypoxia CYP1A1;PLAT;PPARA;CAT;CHRNA7 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0050891| multicellular organismal water homeostasis TRPV4;CFTR GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;ABCC4;UGT1A1;TRPA1;PPARG;CYP1A1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:1902219| PTGS2 GO:0009235| cobalamin metabolic process ABCC1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP2C8;CYP17A1;CYP3A5;HMGCR;CYP3A7;CYP1A2;CYP3A4;UGT2B7 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0097756| PTGS2;HMGCR GO:0010468| regulation of gene expression PPARA;CYP1A2;BCL2 GO:0071456| cellular response to hypoxia PTGS2;BCL2;OPRD1;SLC29A1 GO:0015909| long-chain fatty acid transport PPARG GO:0007568| aging CAT;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CYP1A1 GO:0046697| decidualization PTGS2 GO:0006810| transport CACNA1I;ABCB1;TRPV1;ABCG2;ABCC1;SLC15A1;TRPV2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0048538| thymus development BCL2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0006874| cellular calcium ion homeostasis CHRNA7;BCL2;HTR2A;GPR12;TRPV4;TRPM8 GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;BCL2;PTGS2 GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A3;CYP1A1;CYP2C9;UGT1A1;UGT1A9;CYP2C8;CYP2C19;CYP2D6 GO:0043085| positive regulation of catalytic activity SOD1;BCL2 GO:0032966| negative regulation of collagen biosynthetic process PPARG 17318:[DB14011 DB04863] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0043277| apoptotic cell clearance ALOX15;ITGB3 GO:0007155| cell adhesion CYP1B1;ITGB3;ITGA2B GO:0002576| platelet degranulation ITGB3;ITGA2B;SOD1 GO:0042060| wound healing ALOX15;ITGB3;OPRM1 GO:0060055| angiogenesis involved in wound healing GPX1;ITGB3 GO:0046718| entry of virus into host cell HTR2A;ITGB3 GO:0010745| negative regulation of macrophage derived foam cell differentiation ITGB3;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;HTR2A GO:0016032| viral reproduction HTR2A;ITGB3;VDAC1 GO:0001934| positive regulation of protein phosphorylation ITGB3;CHRNA7 17319:[DB14011 DB00232] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0055085| transmembrane transport SLC12A1;TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;SLC12A1;GLRA1;TRPA1;TRPV1;GLRB GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CA2;SOD1;CYP1A2;PTGS2 GO:0006810| transport TRPV2;SLC12A1;TRPV1;CACNA1I;ABCG2;ABCC1 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:1902476| GLRB;GLRA1;SLC12A1;GLRA3 GO:0006811| ion transport CHRNA7;SLC12A1;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;GLRA1;TRPA1;CACNA1G GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT 17320:[DB14011 DB00838] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00838|Clocortolone NR3C1 common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;NR3C1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 17321:[DB14011 DB04722] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04722|2-(3-CHLORO-6-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-1-OXIDOPYRIDIN-2-YL)-N-[1-(3-CHLOROPHENYL)ETHYL]ACETAMIDE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;F2 17322:[DB14011 DB06935] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0043312| neutrophil degranulation TTR;CAT;ALOX5 GO:0006810| transport TTR;TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process TTR;NAPEPLD 17323:[DB14011 DB04311] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04311|4-Phenylbutylamine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 17324:[DB14011 DB01833] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01833|L-2-Amino-4-(Guanidinooxy)Butyric Acid NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;NOS3;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP2C9;CYP1A1;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0030324| lung development NOS3;CYP1A2 GO:0042311| vasodilation GPX1;NOS3 GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat TRPV1;NOS3;TRPV3;SOD1;TRPV2 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0006809| nitric oxide biosynthetic process NOS3;CYP1B1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1;NOS3 GO:0008217| regulation of blood pressure PPARG;NOS3;SOD1;PTGS2;PTGS1 GO:1902042| NOS3;GPX1 GO:0045454| cell redox homeostasis GPX1;GSR;NOS3 17325:[DB14011 DB00087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0002376| immune system process C1QA;C1QC;FCGR2A;FCGR1A;IDO1;C1QB;C1R GO:0045087| innate immune response C1QA;C1QC;FCGR1A;PPARG;C1R;C1QB GO:0043312| neutrophil degranulation FCGR3B;FCGR2A;ALOX5;CAT GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;FCGR2C;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;FCGR2B;SMPD1;FCGR1A;PLA2G1B;CACNA1I GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;CD52 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;FCGR2B;TRPV1;IDO1;ALOX15 GO:0006955| immune response FCGR2B;FCGR3B;C1R;FCGR1A;C1QC;OPRD1;FCGR2C;FCGR3A;CNR2 GO:0016032| viral reproduction VDAC1;FCGR2B;HTR2A GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B 17326:[DB14011 DB08128] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08128|(1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 17327:[DB14011 DB03439] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03439|4,6-dideoxy-4-amino-alpha-D-glucose AMY1A;AMY2A;AMY2A common genes common pathways GO:0008152| metabolic process AMY1A;ACAT1;AMY2A;SMPD1 17328:[DB14011 DB04925] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04925|Desmoteplase PLG common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;PLG GO:0002576| platelet degranulation PLG;SOD1 GO:0051702| interaction with symbiont GPX1;PLG 17329:[DB14011 DB06981] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06981|(2S)-2-(1H-indol-3-yl)pentanoic acid SKP1 common genes common pathways GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;SKP1 17330:[DB14011 DB01415] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0006810| transport SLC15A2;TRPV2;SLC15A1;ABCC1;ABCG2;TRPV1;CACNA1I GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0051260| protein homooligomerization SLC22A6;GLRA1;GLRA3;ACAT1 GO:0055085| transmembrane transport TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ABCC1;SLC22A6;CACNA1G;SLC15A1;TRPA1;TRPV2;TRPV3;CACNA1H;SLC15A2;SLC22A8 GO:0006811| ion transport SLC22A8;SLC15A2;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;GLRA1;SLC15A1;CACNA1G;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1 GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0098656| SLC22A8;SLC22A6;VDAC1 17331:[DB14011 DB06914] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;HMOX1;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP2C9;CYP1A1;CRYZ GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;HMGCR;PTGS2 GO:0035094| response to nicotine HMOX1;CNR1;CHRNA7 GO:0034605| cellular response to heat TRPV1;TRPV4;HMOX1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;HMOX1;SLC29A1 GO:0051260| protein homooligomerization ACAT1;HMOX1;GLRA3;GLRA1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;HMOX1;SOD1;PTGS2 GO:0006915| apoptotic process GPX1;HMOX1;VDAC1 GO:0008219| cell death HMOX1;HTR2A GO:0045766| positive regulation of angiogenesis CYP1B1;HMOX1;CHRNA7 GO:0001666| response to hypoxia CYP1A1;HMOX1;CAT;CHRNA7 GO:0001525| angiogenesis HMOX1;PTGS2;CYP1B1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;HMOX1;SOD1;CNR1;PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;HMOX1;SOD1 GO:0035556| intracellular signal transduction HMOX1;PLA2G1B GO:0043524| negative regulation of neuron apoptosis SOD1;HMOX1 GO:0006879| cellular iron ion homeostasis ABCG2;HMOX1;SOD1 GO:1904706| PPARG;HMOX1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;HMOX1 GO:0071276| cellular response to cadmium ion SOD1;HMOX1;CYP1A2 GO:0043627| response to estrogen stimulus PPARG;HMOX1 GO:1902042| HMOX1;GPX1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;HMOX1;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;HMOX1;PPARG 17332:[DB14011 DB03937] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03937|Erythose-4-Phosphate kdsA;GPI common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;GPI GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;GPI GO:0007611| learning or memory CHRNA7;CNR1;GPI GO:0043278| response to morphine CNR1;OPRM1;GPI GO:0042593| glucose homeostasis CNR1;PPARG;GPI;TRPV4 GO:0032355| response to estradiol stimulus GPI;PTGS2;CYP1A2;CAT GO:0046686| response to cadmium ion CAT;GPI GO:0001525| angiogenesis PTGS2;CYP1B1;GPI GO:0043524| negative regulation of neuron apoptosis GPI;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;GPX1;PTGS2 17333:[DB14011 DB01837] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01837|O-acetyl-L-serine PTGS1 common genes PTGS1 common pathways GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;PTGS2;CNR2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 17334:[DB14011 DB05943] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05943|Resatorvid CSF2RB;IL2RG common genes common pathways GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;CYP1A1;CSF2RB GO:0016032| viral reproduction HTR2A;IL2RG;VDAC1 GO:0006955| immune response OPRD1;IL2RG;CNR2 GO:0065009| regulation of molecular function IL2RG;CSF2RB;TRPV1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;CSF2RB;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;IL2RG;OPRM1;CNR2 17335:[DB14011 DB09422] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09422|Soybean oil PPARA common genes common pathways GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0001666| response to hypoxia CYP1A1;PPARA;CAT;CHRNA7 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PPARA;PTGS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0042060| wound healing ALOX15;OPRM1;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;PLA2G1B GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT;PPARA GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;PPARA;HMGCR GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;PPARA;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0007507| heart development PPARA;PPARG 17336:[DB14011 DB00098] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;ITGB1;ITGAV GO:0002576| platelet degranulation ITGB3;SOD1 GO:0007155| cell adhesion ITGAV;ITGB1;CD4;ITGAL;CYP1B1;ITGB3 GO:0045087| innate immune response MR1;PPARG GO:0043312| neutrophil degranulation ITGAL;ALOX5;ITGAV;CAT GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B;CD4 GO:0042060| wound healing OPRM1;ALOX15;ITGB3 GO:0046330| positive regulation of JNK cascade TRPV4;FCGR2B GO:0071404| cellular response to low-density lipoprotein particle stimulus ITGB1;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade CD86;GPX1;ITGB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD4 GO:0002376| immune system process MR1;CD86;IDO1;CD1A;CD4 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;ITGAV;HTR2A;GPR12 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;CD4 GO:0043277| apoptotic cell clearance ALOX15;ITGB3;ITGAV GO:0070374| positive regulation of ERK1 and ERK2 cascade CD4;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;ALOX15 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;ITGB1 GO:0043065| positive regulation of apoptotic process ITGB1;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0007166| cell surface receptor linked signaling pathway CD4;TRPV1;TRPA1 GO:0001525| angiogenesis PTGS2;ITGAV;CYP1B1 GO:0006954| inflammatory response ALOX5;PTGS1;ITGAL;CNR2;PTGS2;IDO1;ALOX15;TRPV1;FCGR2B GO:0030217| T cell differentiation GPR18;CD4 GO:0006955| immune response FCGR2B;MR1;CD86;CD1A;CD4;CNR2;OPRD1 GO:0016032| viral reproduction ITGB1;ITGAV;HTR2A;CD4;CD86;VDAC1;ITGB3;FCGR2B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;HTR2A;CD4 GO:0051924| regulation of calcium ion transport OPRD1;CD4 GO:0033674| positive regulation of kinase activity HTR2A;CD4 GO:0008542| visual learning ITGB1;HMGCR GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0001934| positive regulation of protein phosphorylation CD4;CHRNA7;ITGB3 GO:0060055| angiogenesis involved in wound healing ITGB3;GPX1 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;TRPV3;OPRM1;CACNA1H;CHRNA7;ITGAV;TRPV2 GO:0007165| signal transduction FCGR2B;PPARG;GPR18;MR1;SMPD1;CD86;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;GPR12;CNR1;ITGAL;CD4;CNR2;OPRM1;OPRD1;CHRNA7 GO:0046718| entry of virus into host cell HTR2A;ITGAV;ITGB1;ITGB3;CD86 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;OPRM1;ITGAV GO:0033280| response to vitamin D CD4;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation ITGAV;ITGB3;PPARG 17337:[DB14011 DB03245] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP1A1;CYP2C9;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;GCDH;CYP1B1 GO:0019395| fatty acid oxidation PPARG;GCDH GO:0008152| metabolic process SMPD1;GCDH;ACAT1 17338:[DB14011 DB01983] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01983|2(S)-Amino-6-Boronohexanoic Acid ARG1 common genes common pathways GO:0001889| liver development CYP1A1;ARG1;ACAT1 GO:0048678| response to axon injury SOD1;ARG1 GO:0009635| response to herbicide CYP1A1;ARG1 GO:0007565| female pregnancy ARG1;IDO1 GO:0043434| response to peptide hormone stimulus TRPV1;ARG1 GO:0010269| response to selenium ion ARG1;GPX1 GO:0010043| response to zinc ion ARG1;AANAT GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway ARG1;PPARG GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0033197| response to vitamin E ARG1;CAT GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2;ARG1 GO:0030324| lung development ARG1;CYP1A2 GO:0070207| protein homotrimerization TRPM8;ARG1 GO:0043312| neutrophil degranulation ARG1;CAT;ALOX5 GO:0045087| innate immune response ARG1;PPARG GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;ARG1;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0010042| response to manganese ion PTGS2;ARG1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT;ARG1 GO:0009611| response to wounding GPX1;ARG1;CYP1A1 GO:0007568| aging ARG1;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CYP1A1 GO:0002376| immune system process ARG1;IDO1 GO:0043200| response to amino acid stimulus GLRA3;ARG1;GLRB GO:0046686| response to cadmium ion CAT;ARG1 GO:0042130| negative regulation of T cell proliferation ARG1;IDO1 17339:[DB14011 DB02548] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02548|D-glucitol 6-phosphate GPI common genes common pathways GO:0042593| glucose homeostasis GPI;TRPV4;PPARG;CNR1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;GPI GO:0046686| response to cadmium ion GPI;CAT GO:0035902| response to immobilization stress GPI;PPARG;CYP1A1;CYP1A2 GO:0043312| neutrophil degranulation GPI;CAT;ALOX5 GO:0007611| learning or memory GPI;CNR1;CHRNA7 GO:0043278| response to morphine CNR1;OPRM1;GPI GO:0001525| angiogenesis GPI;CYP1B1;PTGS2 GO:0043524| negative regulation of neuron apoptosis GPI;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;GPI 17340:[DB14011 DB04185] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04185|Norvaline OTC;GATM common genes common pathways GO:0001889| liver development CYP1A1;OTC;ACAT1 GO:0031667| response to nutrient levels OTC;SOD1 GO:0010043| response to zinc ion AANAT;OTC GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT;OTC GO:0070207| protein homotrimerization OTC;TRPM8 GO:0007611| learning or memory CNR1;GATM;CHRNA7 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;OTC;SOD1;HTR2A;PTGS2;CYP1A2 17341:[DB14011 DB03903] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03903|Tmr ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 GO:0009612| response to mechanical stimulus ACTA1;PPARG;TRPV4 GO:0010628| positive regulation of gene expression ACTA1;TRPV4 GO:0048741| skeletal muscle fiber development GPX1;ACTA1 GO:0006936| muscle contraction GLRA1;CACNA1H;ACTA1 17342:[DB14011 DB01165] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes CYP1A2;ABCC1 common pathways GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0006641| triglyceride metabolic process CAT;GPX1;SLC22A4 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0098656| SLC22A6;VDAC1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCC1;SLC22A5 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006811| ion transport CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;SLC22A4;TRPV3;CACNA1H;GLRA3;SLC22A5 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0034775| glutathione transmembrane transport ABCC1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;TOP2A;PPARG;SMPD1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0035725| sodium ion transmembrane transport CACNA1H;ABCB11;CACNA1G;CACNA1I GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0009408| response to heat ABCC2;TRPV1;TRPV2;SOD1;TRPV3 GO:0007565| female pregnancy ABCC2;IDO1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1;ABCC2 GO:0010468| regulation of gene expression CYP1A2 GO:0006810| transport ABCC1;ABCC2;ABCG2;TRPV1;CACNA1I;ABCB11;TRPV2 GO:0009235| cobalamin metabolic process ABCC1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0048511| rhythmic process PPARG;TOP2A;AANAT GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0055085| transmembrane transport TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;ABCC2;SLC22A6;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLC22A4;SLC22A5;ABCB11 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;SLC22A4;GLRA3;CHRNA7 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;ABCC2;CYP1A1 GO:0060326| cell chemotaxis ABCC1 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCC2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0099133| ABCC2;ABCC1 17343:[DB14011 DB00671] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;SLC15A1;TRPV2;SLC15A2 GO:0055085| transmembrane transport SLC22A5;SLC15A2;TRPV3;CACNA1H;TRPV2;SLC15A1;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;CACNA1I;TRPV4;VDAC1 GO:0006811| ion transport TRPV3;CACNA1H;SLC22A5;SLC15A2;GLRA3;TRPV2;CHRNA7;CACNA1G;SLC15A1;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8 GO:0006855| drug transmembrane transport SLC22A5;ABCG2;ABCC1 17344:[DB14011 DB05801] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05801|GTI 2040 RRM2 common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;RRM2;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0015949| nucleobase-containing small molecule interconversion GSR;RRM2 17345:[DB14011 DB01959] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;PDE4B;CACNA1I;PLA2G1B;HTR2A;GPR12;CNR1;GPR55;HTR1A;PDE4D;OPRD1;CNR2;OPRM1;CHRNA7 GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0007568| aging HMGCR;PDE4D;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CAT;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PDE4B;GPR18;PPARG;OPRD1;PDE4D;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B;PDE4D 17346:[DB14011 DB08894] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08894|Peginesatide EPOR common genes common pathways GO:0046697| decidualization EPOR;PTGS2 GO:0007507| heart development PPARG;EPOR GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;EPOR;GPR12;CNR1;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0007420| brain development ACAT1;EPOR 17347:[DB14011 DB07546] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways GO:0006351| transcription, DNA-dependent CSNK2A2;PPARG GO:0016236| macroautophagy CSNK2A2;VDAC1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A2;PPARG GO:0006915| apoptotic process CSNK2A2;VDAC1;GPX1 GO:0007283| spermatogenesis CSNK2A2;CNR1;SOD1 GO:1903146| VDAC1;CSNK2A2 17348:[DB14011 DB05111] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05111|Fontolizumab IFNG common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;IFNG GO:0008284| positive regulation of cell proliferation IFNG;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0009615| response to virus IFNG;CYP1A1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;IFNG GO:0006915| apoptotic process VDAC1;GPX1;IFNG GO:0045892| negative regulation of transcription, DNA-dependent IFNG;PPARG GO:0010628| positive regulation of gene expression IFNG;TRPV4 GO:0032735| positive regulation of interleukin-12 production IFNG;IDO1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;IFNG GO:0001934| positive regulation of protein phosphorylation IFNG;CHRNA7 GO:0010629| negative regulation of gene expression IFNG;OPRD1 GO:0006955| immune response IFNG;CNR2;OPRD1 GO:0000060| protein import into nucleus, translocation IFNG;OPRD1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNG GO:0050796| regulation of insulin secretion IFNG;CNR1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IFNG 17349:[DB14011 DB03600] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes PPARG common pathways GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0098869| PTGS1;GPX1;CAT;PTGS2;ALB;GSR GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0006687| glycosphingolipid metabolic process SMPD1;GLTP GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG GO:0045087| innate immune response PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0032526| response to retinoic acid PPARG GO:0030308| negative regulation of cell growth PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0030224| monocyte differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0060694| regulation of cholesterol transporter activity PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:1905461| PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;PPARG GO:0055088| lipid homeostasis PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0001895| retina homeostasis SOD1;ALB GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;FURIN GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;PTGS1;NAAA;GPX1;PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0048469| cell maturation PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG 17350:[DB14011 DB01436] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP27B1;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;VDR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;VDR GO:0032526| response to retinoic acid RXRA;PPARG GO:0030308| negative regulation of cell growth PPARG;CYP27B1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;CYP1A2;CYP27B1;OPRM1 GO:0008203| cholesterol metabolic process CAT;HMGCR;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;RXRA;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;RXRA;VDR GO:0036378| CYP3A4;CYP27B1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;VDR GO:0042359| vitamin D metabolic process CYP27B1;CYP3A4;CYP1A1;GC GO:0010628| positive regulation of gene expression VDR;TRPV4 GO:0030282| bone mineralization CYP27B1;PTGS2;ALOX15 GO:0046697| decidualization PTGS2;CYP27B1;VDR GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;VDR;GPR12;HTR2A GO:0007595| lactation SLC29A1;VDR GO:0016032| viral reproduction RXRA;VDAC1;HTR2A GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1;TRPV3;CACNA1H;CYP27B1;CHRNA7;VDR;TRPV2 GO:0051289| protein homotetramerization TRPV1;TRPM8;TRPA1;RXRA;CRYZ;CAT GO:0006351| transcription, DNA-dependent RXRA;PPARG;VDR GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;VDR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0007507| heart development PPARG;RXRA GO:0033280| response to vitamin D CYP27B1;PTGS2 GO:0008285| negative regulation of cell proliferation VDR;CYP27B1;OPRM1;PTGS2;CYP1B1;PPARG GO:0043627| response to estrogen stimulus PPARG;CYP27B1 GO:0001890| placenta development PPARG;RXRA;SOD1 GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0007566| embryo implantation PTGS2;SOD1;RXRA GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;RXRA;PPARG;CYP1A1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;VDR;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0043010| camera-type eye development RXRA;CYP1A1 17351:[DB14011 DB03975] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03975|Mercuribenzoic Acid CA2 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;PPARG;CYP1A1;CA2 GO:0001822| kidney development CA2;CAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 17352:[DB14011 DB09069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09069|Trimetazidine ACAA1 common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;ACAA1 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;ACAA1;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0043312| neutrophil degranulation ACAA1;ALOX5;CAT GO:0006635| fatty acid beta-oxidation ACAA1;ACAT1 GO:0006631| fatty acid metabolic process ACAA1;PTGS1;PTGS2;ALOX15 17353:[DB14011 DB08256] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways GO:0006954| inflammatory response CNR2;PTGS2;EPHX2;ALOX5;PTGS1;TRPV1;ALOX15;IDO1 GO:0008152| metabolic process SMPD1;EPHX2;ACAT1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;EPHX2;CYP3A4;CYP1A2;CYP3A7 GO:0006629| lipid metabolic process EPHX2;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;NAAA;GPX1;PTGS1;PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;EPHX2 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;EPHX2;SOD1 GO:0072593| reactive oxygen species metabolic process EPHX2;SOD1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;EPHX2;CYP1A2 GO:0010628| positive regulation of gene expression TRPV4;EPHX2 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;GPR12;HTR2A;EPHX2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;EPHX2;CYP2D6;CYP2C19;CYP2C9;CYP1A1 17354:[DB14011 DB02563] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02563|Hexanoyl-CoA ECHS1 common genes common pathways GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ECHS1;ALOX15 GO:0006635| fatty acid beta-oxidation ACAT1;ECHS1 GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;DAGLA;ECHS1;CYP2D6;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;NAAA;PTGS1;GPX1 GO:0008152| metabolic process ACAT1;ECHS1;SMPD1 17355:[DB14011 DB07830] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043542| endothelial cell migration DPP4;CYP1B1 17356:[DB14011 DB02087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02087|3,5-Difluorobenzenesulfonamide CA2 common genes common pathways GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1;CA2 GO:0001822| kidney development CAT;CA2 17357:[DB14011 DB12450] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12450|Propyl Gallate ESR1 common genes common pathways GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV1;TRPV4 GO:0007165| signal transduction ESR1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV4;TRPV1;PPARG 17358:[DB14011 DB05258] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05258|Natural alpha interferon IFNAR1 common genes common pathways GO:0009615| response to virus IFNAR1;CYP1A1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;OPRM1;IFNAR1;CYP1A2;PTGS2;CNR2 17359:[DB14011 DB07233] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07233|N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan ADAM17 common genes common pathways GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;ADAM17 GO:0002446| neutrophil mediated immunity PLA2G1B;ADAM17 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;ADAM17 GO:0042493| response to drug ABCG2;TRPA1;ADAM17;CYP1A1;PPARG;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0007155| cell adhesion CYP1B1;ADAM17 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;ADAM17 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;CYP1A1;ADAM17;IDO1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ADAM17 17360:[DB14011 DB08936] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08936|Chlorcyclizine HRH1 common genes common pathways GO:0007613| memory HTR2A;CNR1;HRH1;PTGS2;CHRNA7 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HRH1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0045907| positive regulation of vasoconstriction HTR2A;HRH1;PTGS2 GO:0008542| visual learning HMGCR;HRH1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ALOX5;PTGS1;CNR2;PTGS2;HRH1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;HRH1;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;HRH1;OPRM1;HTR2A 17361:[DB14011 DB04608] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04608|9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE WEE1 common genes common pathways 17362:[DB14011 DB09160] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2;ABCB1 GO:0055085| transmembrane transport CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H GO:0006810| transport TRPV2;ABCG2;ABCB1;CACNA1I;TRPV1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 17363:[DB14011 DB12872] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0055093| response to hyperoxia COL1A1;CYP1A1;CAT GO:0045893| positive regulation of transcription, DNA-dependent PPARG;COL1A1 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;COL1A1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;F8;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;PTGS1;ALOX5;GPX1 GO:0071300| cellular response to retinoic acid COL1A1;PPARG GO:0009612| response to mechanical stimulus COL1A1;TRPV4;PPARG GO:0002576| platelet degranulation F8;SOD1 GO:0042060| wound healing OPRM1;COL1A1;ALOX15 GO:0071306| cellular response to vitamin E PPARG;COL1A1 GO:0030199| collagen fibril organization COL1A1;CYP1B1 GO:0071230| cellular response to amino acid stimulus COL1A1;GLRA1 GO:0071356| cellular response to tumor necrosis factor ADAMTS13;COL1A1;TRPV1 GO:0051591| response to cAMP COL1A1;AANAT GO:0034612| response to tumor necrosis factor ADAMTS13;PTGS2 GO:0007605| sensory perception of sound COL1A1;SOD1;GPX1 GO:0032355| response to estradiol stimulus COL1A1;PTGS2;CYP1A2;CAT GO:0031667| response to nutrient levels COL1A1;SOD1 GO:0060351| cartilage development involved in endochondral bone morphogenesis TRPV4;COL1A1 GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;COL1A1;TRPA1 GO:0071260| cellular response to mechanical stimulus COL1A1;PTGS2 GO:0001503| ossification ALOX15;COL1A1 GO:0007584| response to nutrient HMGCR;CNR1;COL1A1;PPARG GO:0009636| response to toxin CAT;ADAMTS13;GPX1;CYP1B1;CYP1A1 GO:0043434| response to peptide hormone stimulus TRPV1;COL1A1 GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1;COL1A1 GO:0001649| osteoblast differentiation CAT;COL1A1 17364:[DB14011 DB00135] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0035094| response to nicotine CNR1;TH;CHRNA7 GO:0035900| response to isolation stress NAPEPLD;TH GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;TH;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 GO:0042493| response to drug CAT;TH;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0006631| fatty acid metabolic process PTGS2;TH;PTGS1;ALOX15 GO:0035902| response to immobilization stress TH;CYP1A2;PPARG;CYP1A1 GO:0070848| response to growth factor stimulus OPRM1;TH GO:0007626| locomotory behavior SOD1;TH;OPRM1 GO:0071333| cellular response to glucose stimulus SLC29A1;TH GO:0007612| learning TH;PTGS2;VDAC1 GO:0032496| response to lipopolysaccharide CNR1;TH;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0009416| response to light stimulus AANAT;TH GO:0001666| response to hypoxia TH;CHRNA7;CAT;CYP1A1 GO:0055085| transmembrane transport CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;SLC16A2;CACNA1H;SLC16A10;TRPV3 GO:0006915| apoptotic process YARS;VDAC1;GPX1 GO:0007605| sensory perception of sound GPX1;TH;SOD1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;TAT GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;SLC16A2 GO:0032355| response to estradiol stimulus TH;CYP1A2;PTGS2;CAT GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1;TH GO:0031667| response to nutrient levels TH;SOD1 GO:0009635| response to herbicide TH;CYP1A1 GO:0007507| heart development PPARG;TH GO:0071312| cellular response to alkaloid TH;TRPV1 GO:0042136| neurotransmitter biosynthetic process DAGLA;TH GO:0045471| response to ethanol CAT;OPRM1;HMGCR;TH;SOD1;CNR1 GO:0008016| regulation of heart contraction TH;CACNA1H GO:0014823| response to activity TH;CAT GO:0010043| response to zinc ion TH;AANAT GO:0042755| eating behavior OPRD1;OPRM1;TH GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;TH;TAT;TRPA1;CYP1A1;PPARG GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;YARS GO:0051412| response to corticosterone stimulus TH;AANAT GO:0033076| isoquinoline alkaloid metabolic process TH;CYP2D6 GO:0007613| memory CNR1;TH;HTR2A;PTGS2;CHRNA7 GO:0007601| visual perception TH;CRYZ;GLRA1;CYP1B1;GLRB GO:0051384| response to glucocorticoid stimulus PTGS2;TAT GO:0050890| cognition CHRNA7;TH GO:0001975| response to amphetamine TH;SOD1;CNR2 GO:0043434| response to peptide hormone stimulus TRPV1;TH 17365:[DB14011 DB02340] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02340|N-Acetyl-Serine F13A1 common genes common pathways GO:0002576| platelet degranulation SOD1;F13A1 17366:[DB14011 DB07521] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07521|6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL F2 common genes common pathways GO:0061844| F2;PLA2G1B GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0008284| positive regulation of cell proliferation F2;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 17367:[DB14011 DB06477] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways GO:0001975| response to amphetamine DRD2;DRD3;DRD4;SOD1;CNR2 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;DRD3;HMGCR;CNR1 GO:0040014| regulation of multicellular organism growth DRD3;SOD1 GO:1900273| DRD2;CHRNA7 GO:0050482| arachidonic acid secretion DRD4;DRD3;PLA2G1B;DRD2 GO:0007165| signal transduction DRD2;CACNA1I;PLA2G1B;PPARG;DRD3;GPR18;SMPD1;CHRNA7;DRD4;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0009636| response to toxin CAT;GPX1;CYP1A1;DRD2;CYP1B1 GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0014854| response to inactivity CAT;DRD2 GO:0008344| adult locomotory behavior OPRD1;DRD4 GO:0042053| regulation of dopamine metabolic process HTR1A;DRD4 GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0001662| behavioral fear response HTR1A;DRD4;VDAC1 GO:0008285| negative regulation of cell proliferation DRD2;CYP1B1;PPARG;PTGS2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0045776| negative regulation of blood pressure DRD2;DRD3;CNR1 GO:0045471| response to ethanol DRD3;DRD2;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0048678| response to axon injury DRD2;SOD1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0001659| temperature homeostasis DRD2;TRPV1;GPX1;HTR2A GO:0048148| behavioral response to cocaine DRD3;DRD2;HTR2A;DRD4 GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0048149| behavioral response to ethanol DRD2;OPRM1;DRD4 GO:0001964| startle response GLRB;DRD2;GLRA1 GO:0033674| positive regulation of kinase activity DRD4;HTR2A GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0008542| visual learning DRD3;DRD2;HMGCR GO:0007186| G-protein coupled receptor signaling pathway DRD2;PPARG;DRD3;GPR18;HTR1A;GPR55;DRD4;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;DRD2;TRPV1;TRPA1 GO:0006874| cellular calcium ion homeostasis TRPV4;DRD2;TRPM8;DRD3;CHRNA7;DRD4;HTR2A;GPR12 GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TRPV4;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0000187| activation of MAPK activity CHRNA7;DRD4;SOD1;PLA2G1B GO:0042220| response to cocaine DRD2;SMPD1;DRD3;OPRM1;CNR1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DRD2 GO:0009416| response to light stimulus DRD2;AANAT GO:0048511| rhythmic process PPARG;DRD4;AANAT GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;DRD2;GPR18 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;DRD4 GO:0014059| regulation of dopamine secretion DRD2;DRD3;HTR2A GO:0007612| learning DRD3;VDAC1;PTGS2 GO:0007611| learning or memory CNR1;CHRNA7;DRD3 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;DRD2;GLRB;TRPV1;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;PPARG;DRD3 GO:0007626| locomotory behavior OPRM1;SOD1;DRD2;DRD3 GO:0008284| positive regulation of cell proliferation DRD3;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;PPARG;TRPV4;TRPV1 GO:0007628| adult walking behavior DRD2;GLRB;GLRA1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0042493| response to drug ABCG2;DRD2;DRD3;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0043278| response to morphine OPRM1;CNR1;DRD2;DRD3 17368:[DB14011 DB02483] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0042542| response to hydrogen peroxide TRPA1;LDHA;SOD1;CAT;GPX1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;LDHA;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0050727| regulation of inflammatory response PTGS2;BST1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;BST1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;LDHA;CYP1A2;PTGS2;AANAT;ACAT1 GO:0007584| response to nutrient PPARG;LDHA;CNR1;HMGCR GO:0043627| response to estrogen stimulus PPARG;LDHA GO:0043312| neutrophil degranulation CAT;ALOX5;BST1 GO:0008284| positive regulation of cell proliferation BST1;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0055114| oxidation-reduction process LDHA;CYP1A1;CYP2C9;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;LDHA;ABCG2 GO:0051591| response to cAMP AANAT;LDHA GO:0001666| response to hypoxia LDHA;CYP1A1;CHRNA7;CAT 17369:[DB14011 DB07092] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 17370:[DB14011 DB00654] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0043066| negative regulation of apoptotic process CAT;GPX1;PTGFR;SOD1;PTGS2;HMGCR GO:0008284| positive regulation of cell proliferation CHRNA7;PTGFR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1;PTGFR GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A1;GLRA1 GO:0032355| response to estradiol stimulus PTGFR;CAT;PTGS2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PTGFR;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0010628| positive regulation of gene expression PTGFR;TRPV4 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;SLC22A1;ABCC1;CACNA1G;TRPM8;SLCO2B1;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4 GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;PTGFR;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0006812| cation transport SLC22A1;TRPM8 GO:0006811| ion transport SLC22A1;CACNA1G;TRPA1;GLRA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;SLCO2B1;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7 GO:0006855| drug transmembrane transport SLC22A1;ABCC1;ABCG2 17371:[DB14011 DB07907] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07907|(2S)-2-HYDROXYOCTANOIC ACID HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A2;CYP3A7;PTGS2;HAO1;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0006979| response to oxidative stress SOD1;PTGS2;HAO1;CAT;GPX1;PTGS1 17372:[DB14011 DB02848] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02848|{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol FBP1 common genes common pathways GO:0051289| protein homotetramerization FBP1;CAT;TRPV1;TRPM8;TRPA1;CRYZ GO:0008152| metabolic process SMPD1;ACAT1;FBP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;FBP1 GO:0030308| negative regulation of cell growth FBP1;PPARG 17373:[DB14011 DB04363] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;BLVRB;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 17374:[DB14011 DB09269] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09269|Phenylacetic acid CES1 common genes common pathways GO:0009636| response to toxin CAT;GPX1;CES1;CYP1B1;CYP1A1 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0008152| metabolic process ACAT1;CES1;SMPD1 GO:0030855| epithelial cell differentiation VDAC1;PPARG;CES1 GO:0006695| cholesterol biosynthetic process HMGCR;CES1 17375:[DB14011 DB07255] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07255|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3-MORPHOLIN-4-YLPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0001525| angiogenesis CYP1B1;EPHB4;PTGS2 GO:0007155| cell adhesion CYP1B1;EPHB4 17376:[DB14011 DB01099] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01099|Flucytosine DNMT1 common genes common pathways GO:0006351| transcription, DNA-dependent DNMT1;PPARG GO:0010468| regulation of gene expression CYP1A2;DNMT1 GO:0010628| positive regulation of gene expression TRPV4;DNMT1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;DNMT1 GO:0032259| methylation DNMT1;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;PPARG;TRPV1;TRPV4 GO:0042127| regulation of cell proliferation DNMT1;PTGS1;PTGS2 GO:0071230| cellular response to amino acid stimulus DNMT1;GLRA1 GO:0006355| regulation of transcription, DNA-dependent DNMT1;PPARG 17377:[DB14011 DB07458] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07458|3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione PRKACA common genes common pathways GO:0034605| cellular response to heat TRPV1;TRPV4;PRKACA;PTGS2 GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0002027| regulation of heart rate PRKACA;CACNA1G 17378:[DB14011 DB02857] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02857|Guanosine PNP common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;PNP GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;PNP;TRPA1;ABCG2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0006955| immune response PNP;OPRD1;CNR2 17379:[DB14011 DB07129] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07129|(2R)-1-(2,6-dimethylphenoxy)propan-2-amine PLAU common genes common pathways GO:0001666| response to hypoxia PLAU;CYP1A1;CAT;CHRNA7 GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;PLAU;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7 17380:[DB14011 DB12836] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways GO:0006810| transport ABCC1;ABCB1;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0007186| G-protein coupled receptor signaling pathway PTGER4;GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0098869| PTGS2;CAT;PTGS1;GPX1;ALB;GSR GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;ABCB1;CACNA1I;TRPV4;TRPV1;TRPA1;ABCC1;CACNA1G;TRPV2;TRPV3;CACNA1H GO:0032496| response to lipopolysaccharide CYP1A1;PTGER4;IDO1;CNR1;PTGS2;CNR2;CYP1A2;OPRM1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;ALB GO:0009612| response to mechanical stimulus TRPV4;PTGER4;PPARG GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;ABCB1 GO:0050728| negative regulation of inflammatory response PTGER4;CNR2 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0050729| positive regulation of inflammatory response TRPV4;PTGER4 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;PTGER4;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0001895| retina homeostasis SOD1;ALB GO:0071380| cellular response to prostaglandin E stimulus PPARG;PTGER4 GO:0071260| cellular response to mechanical stimulus PTGS2;PTGER4 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;PTGER4 GO:0006955| immune response PTGER4;CNR2;OPRD1 17381:[DB14011 DB06281] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06281|Torcetrapib CETP;CYP11B2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;CYP11B2;HMGCR;CYP17A1;CYP3A5;CETP;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9 GO:0008203| cholesterol metabolic process HMGCR;CAT;CETP GO:0006694| steroid biosynthetic process CYP11B2;HMGCR;CYP17A1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP11B2;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0032342| aldosterone biosynthetic process CACNA1H;CYP11B2 GO:0032870| cellular response to hormone stimulus CYP11B2;CACNA1H GO:0006641| triglyceride metabolic process CETP;GPX1;CAT GO:0055088| lipid homeostasis PPARG;CETP GO:0035865| cellular response to potassium ion CYP11B2;CACNA1H;SOD1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;CETP GO:0046470| phosphatidylcholine metabolic process PLA2G1B;CETP GO:0016125| sterol metabolic process CYP11B2;CYP1B1;CYP17A1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;CYP11B2;HMGCR;CYP1A2;PTGS2;CETP;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0034651| cortisol biosynthetic process CYP11B2;CACNA1H 17382:[DB14011 DB03064] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03064|3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline HAO1 common genes common pathways GO:0006979| response to oxidative stress PTGS2;HAO1;SOD1;PTGS1;GPX1;CAT GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;HAO1;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1 17383:[DB14011 DB00139] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0006936| muscle contraction CACNA1H;ASPH;GLRA1 GO:0006810| transport TRPV2;ABCC1;SLC13A2;ABCG2;TRPV1;CACNA1I GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1;HSD17B6;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;SUCNR1;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0009060| aerobic respiration SDHC;SDHB;CAT GO:0001666| response to hypoxia CAT;CHRNA7;PLOD1;CYP1A1 GO:0055085| transmembrane transport TRPA1;CACNA1G;SLC13A2;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;SLC22A8;SLC13A3;CACNA1H;TRPV3;SLC13A1;TRPV2 GO:0034220| ion transmembrane transport ASPH;CHRNA7;GLRA3;TRPV1;GLRB;TRPA1;GLRA1 GO:0042594| response to starvation ACAT1;PPARG;OXCT1 GO:0042311| vasodilation GPX1;PLOD3 GO:0030199| collagen fibril organization P4HA1;CYP1B1;PLOD3 GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B;ASPH GO:0055114| oxidation-reduction process SDHC;CRYZ;CYP1A1;CYP2C9;CYP2D6;BBOX1;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;P3H1;P4HA1;ALDH5A1;CYP1B1;SDHA;P3H3;SOD1;SDHD;TMLHE;CYP3A4;HMGCR;CYP3A7;P4HA2;PTGS2;PLOD1;CYP1A2;P3H2;PLOD3;CAT;SDHB;ASPH;HSD17B6;ALOX5;PTGS1;GPX1 GO:0022900| electron transport chain SDHA;P4HA2;CYP1A2;ASPH;HSD17B6;IDO1;GSR GO:0045893| positive regulation of transcription, DNA-dependent ASPH;PPARG GO:0042493| response to drug OXCT1;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0009725| response to hormone stimulus ACAT1;OXCT1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SUCNR1;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0007420| brain development ACAT1;OXCT1 GO:0032870| cellular response to hormone stimulus PLOD3;CACNA1H GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;CACNA1H;OPRM1;TRPV3;CHRNA7;TRPV2;ASPH GO:0014823| response to activity OXCT1;CAT GO:0098656| VDAC1;SLC13A2;SLC22A8 GO:0008285| negative regulation of cell proliferation P3H1;CYP1B1;PPARG;ASPH;P3H3;PTGS2;P3H2;OPRM1 GO:0007584| response to nutrient PPARG;OXCT1;CNR1;HMGCR GO:0046952| ketone body catabolic process OXCT2;OXCT1;ACAT1 GO:0060612| adipose tissue development OXCT1;ACAT1 GO:0006749| glutathione metabolic process GPX1;SOD1;ALDH5A1;GSR GO:0009791| post-embryonic development CYP1A2;ALDH5A1 GO:0006702| androgen biosynthetic process HSD17B6;CYP17A1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC22A8 GO:0006811| ion transport VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;SLC13A2;SLC25A10;TRPA1;GLRA1;TRPV2;SLC13A1;CHRNA7;CACNA1H;SLC13A3;TRPV3;SLC22A8;GLRA3 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HSD17B6;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0007399| nervous system development SMPD1;GLRB;SDHA GO:0007507| heart development OXCT1;PPARG GO:0008152| metabolic process ALDH5A1;OXCT1;OXCT2;SMPD1;SUCLG1;ACAT1;SUCLG2;SUCLA2 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SLC13A1;CACNA1H GO:0071277| cellular response to calcium ion ASPH;ALOX15 GO:0045471| response to ethanol OXCT1;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPV1;ALDH5A1;TRPM8;CAT 17384:[DB14011 DB02110] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes PTGS1 common pathways GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;TRPV1;ALOX15;IDO1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0045333| cellular respiration CYP1A2;CYCS GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYCS;ALOX5;GPX1;PTGS1;CAT GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0034599| cellular response to oxidative stress CAT;GPX1;CYCS;SOD1;GSR GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0006915| apoptotic process GPX1;CYCS;VDAC1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR 17385:[DB14011 DB01854] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01854|5-Bromonicotinamide ART1 common genes common pathways 17386:[DB14011 DB06156] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SLC6A4;SMPD1;SLC6A2;ABCC1;TRPA1;PPARG;CYP1A1;SLC6A3;ABCG2 GO:0048265| response to pain TRPA1;SLC6A2;TRPV1 GO:0035094| response to nicotine SLC6A3;CHRNA7;CNR1 GO:0007623| circadian rhythm AANAT;SLC6A4 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007626| locomotory behavior SLC6A3;OPRM1;SOD1 GO:0042220| response to cocaine SMPD1;SLC6A3;CNR1;OPRM1 GO:0055085| transmembrane transport TRPV1;VDAC1;TRPV4;CACNA1I;SLC6A3;TRPM8;ABCG2;SLC6A2;ABCC1;CACNA1G;TRPA1;TRPV2;SLC6A4;TRPV3;CACNA1H GO:0051591| response to cAMP AANAT;SLC6A3 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SLC6A4;SOD1;CYP1A2;PTGS2 GO:0001666| response to hypoxia CHRNA7;CAT;SLC6A4;CYP1A1 GO:0010628| positive regulation of gene expression SLC6A4;TRPV4 GO:0007568| aging SLC6A3;CYP1A1;CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR GO:0006810| transport TRPV2;CACNA1I;TRPV1;ABCG2;ABCC1;SLC6A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;SLC6A4;CAT GO:0051260| protein homooligomerization SLC6A4;ACAT1;GLRA3;GLRA1 GO:0007268| synaptic transmission GLRB;VDAC1;GLRA1;SLC6A2;CACNA1G;GLRA3;HTR2A;OPRD1;OPRM1 GO:0007595| lactation SLC6A3;SLC29A1 GO:0045471| response to ethanol SLC6A3;CAT;OPRM1;HMGCR;SOD1;CNR1 GO:0042136| neurotransmitter biosynthetic process SLC6A3;DAGLA;SLC6A4 GO:0042310| vasoconstriction SLC6A4;HTR1A GO:0014070| response to organic cyclic compound SLC6A3;CYP1A1;PPARG;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC6A4 GO:0007584| response to nutrient HMGCR;CNR1;SLC6A4;PPARG GO:0042053| regulation of dopamine metabolic process SLC6A3;HTR1A GO:0007613| memory CNR1;HTR2A;PTGS2;SLC6A4;CHRNA7 GO:0007420| brain development SLC6A4;ACAT1 17387:[DB14011 DB01430] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;ATP1A1;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0086002| CACNA1G;ATP1A1 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;ATP1A1;GLRB;TRPV1;GLRA1;TRPA1 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0008217| regulation of blood pressure PTGS1;SOD1;ATP1A1;PTGS2;PPARG GO:0006811| ion transport CACNA1H;TRPV3;ATP1A1;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8 17388:[DB14011 DB04234] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04234|N2-({[(4-Bromophenyl)Methyl]Oxy}Carbonyl)-N1-[(1s)-1-Formylpentyl]-L-Leucinamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;GPR55 GO:1903146| CTSK;VDAC1 17389:[DB14011 DB13164] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13164|Olmutinib EGFR common genes common pathways GO:0050729| positive regulation of inflammatory response EGFR;TRPV4 GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;EGFR GO:0007165| signal transduction EGFR;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;EGFR GO:0008283| cell proliferation EGFR;CYP1A1;GPX1;HTR1A GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1;EGFR GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;EGFR GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;EGFR GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;PPARG GO:0007166| cell surface receptor linked signaling pathway TRPA1;EGFR;TRPV1 GO:0001889| liver development EGFR;CYP1A1;ACAT1 GO:0051592| response to calcium ion EGFR;AANAT GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0001503| ossification ALOX15;EGFR GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7 GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;CAT;OPRD1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;EGFR GO:0033993| response to lipid PPARG;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TRPV1;PTGS2;OPRM1 GO:0006979| response to oxidative stress EGFR;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;EGFR GO:0007202| activation of phospholipase C activity HTR2A;GPR55;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0042060| wound healing OPRM1;ALOX15;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS2;PTGS1 GO:0007623| circadian rhythm EGFR;AANAT GO:0007611| learning or memory CNR1;CHRNA7;EGFR GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0030324| lung development EGFR;CYP1A2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;EGFR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR 17390:[DB14011 DB09334] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09334|Seractide acetate MC2R common genes common pathways GO:0001890| placenta development MC2R;PPARG;SOD1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;CACNA1I;PLA2G1B;MC2R;SMPD1;GPR18;PPARG GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;MC2R;GLRA1;GLRB GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger MC2R;OPRD1;CNR2;OPRM1;CNR1 GO:0007186| G-protein coupled receptor signaling pathway MC2R;PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 17391:[DB14011 DB03752] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes PTGS1 common pathways GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;IDO1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ;ALOX5;PTGS1;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0098869| GSR;CAT;PTGS1;GPX1;PTGS2 17392:[DB14011 DB08291] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08291|N-(3-AMINOPROPYL)-2-NITROBENZENAMINE KAT2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter KAT2B;PPARG;PLA2G1B GO:0006367| transcription initiation from RNA polymerase II promoter KAT2B;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;KAT2B GO:0045893| positive regulation of transcription, DNA-dependent KAT2B;PPARG GO:0048511| rhythmic process KAT2B;AANAT;PPARG GO:0006351| transcription, DNA-dependent PPARG;KAT2B GO:0016032| viral reproduction HTR2A;KAT2B;VDAC1 GO:0032869| cellular response to insulin stimulus KAT2B;PLA2G1B;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;KAT2B;OPRM1;PTGS2 17393:[DB14011 DB03150] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03150|2',3'-Dideoxythymidine-5'-Monophosphate DTYMK common genes common pathways GO:0046686| response to cadmium ion CAT;DTYMK GO:0071363| cellular response to growth factor stimulus DTYMK;TRPV1;OPRD1;CAT GO:0045445| myoblast differentiation HMGCR;DTYMK GO:0008283| cell proliferation CYP1A1;DTYMK;GPX1;HTR1A GO:0015949| nucleobase-containing small molecule interconversion GSR;DTYMK GO:0043627| response to estrogen stimulus PPARG;DTYMK 17394:[DB14011 DB04614] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0008283| cell proliferation GPX1;ACHE;HTR1A;CYP1A1 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0051262| protein tetramerization CAT;HMGCR;ACHE GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0007517| muscle organ development CACNA1H;ACHE GO:0007155| cell adhesion ACHE;CYP1B1 17395:[DB14011 DB08005] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08005|4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide MAPK10 common genes common pathways GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B;MAPK10 GO:0009416| response to light stimulus MAPK10;AANAT GO:0048511| rhythmic process PPARG;MAPK10;AANAT GO:0010468| regulation of gene expression CYP1A2;MAPK10 GO:0042752| regulation of circadian rhythm PPARG;MAPK10 GO:0007165| signal transduction MAPK10;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 17396:[DB14011 DB00493] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC22A8 GO:0006811| ion transport TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA1;TRPA1;SLC15A1;CACNA1G;SLC22A11;CHRNA7;SLC22A7;TRPV2;SLC22A8;SLC15A2;GLRA3;TRPV3;CACNA1H GO:0001895| retina homeostasis SOD1;ALB GO:0098656| SLC22A6;VDAC1;SLC22A8;SLC22A7 GO:0043066| negative regulation of apoptotic process ALB;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0002576| platelet degranulation SOD1;ALB GO:0006810| transport SLC15A2;TRPV2;SLC15A1;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0098869| ALB;GSR;PTGS1;GPX1;CAT;PTGS2 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0055085| transmembrane transport ABCC1;SLC22A6;CACNA1G;SLC15A1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCG2;TRPV3;CACNA1H;SLC22A8;SLC15A2;TRPV2;SLC22A11;SLC22A7 17397:[DB14011 DB06848] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways 17398:[DB14011 DB08695] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways GO:0001516| prostaglandin biosynthetic process PTGS1;HPGDS;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;HPGDS;PLA2G1B GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;HPGDS;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0019371| cyclooxygenase pathway PTGS1;HPGDS;PTGS2 GO:0006693| prostaglandin metabolic process HPGDS;PTGS1;PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;NAAA;GPX1;PTGS1;HPGDS;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1;HPGDS GO:0007626| locomotory behavior HPGDS;OPRM1;SOD1 17399:[DB14011 DB07145] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07145|(2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE ADAM17 common genes common pathways GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;ADAM17 GO:0002446| neutrophil mediated immunity PLA2G1B;ADAM17 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;ADAM17 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;ADAM17;PPARG GO:0007155| cell adhesion CYP1B1;ADAM17 GO:0008284| positive regulation of cell proliferation ADAM17;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;ADAM17;CYP1A1 GO:0001934| positive regulation of protein phosphorylation ADAM17;CHRNA7 17400:[DB14011 DB05785] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;JUN;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0007623| circadian rhythm JUN;AANAT GO:0007612| learning VDAC1;JUN;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;JUN GO:0032526| response to retinoic acid RARA;RARG;PPARG GO:0008284| positive regulation of cell proliferation JUN;HMGCR;PTGS2;HTR2A;HTR1A;RARA;RARG;CHRNA7;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter JUN;RARA;RARG;PPARG;PLA2G1B;RARB GO:0009612| response to mechanical stimulus PPARG;TRPV4;JUN GO:0043066| negative regulation of apoptotic process RARA;GPX1;RARG;CAT;JUN;HMGCR;PTGS2;SOD1;RARB GO:0071300| cellular response to retinoic acid PPARG;RARG;RARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;RARA;TRPV1;TRPV4;RARB;PPARG GO:0034097| response to cytokine stimulus PTGS2;JUN;AANAT;RARA GO:0006355| regulation of transcription, DNA-dependent RARA;RARG;JUN;RARB;PPARG GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;JUN;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RARA;JUN GO:0030224| monocyte differentiation PPARG;JUN GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;JUN GO:0006367| transcription initiation from RNA polymerase II promoter RARA;RARG;RARB;PPARG GO:0033189| response to vitamin A RARA;CAT;CYP1A1;PPARG GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;RARA GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0007568| aging CYP1A1;CAT;HMGCR;JUN;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7;RARA GO:0051591| response to cAMP JUN;AANAT GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;JUN;HMGCR;OPRM1;CHRNA7 GO:0001657| ureteric bud development RARA;CAT;RARB GO:0043277| apoptotic cell clearance RARA;ALOX15 GO:0007283| spermatogenesis RARA;CNR1;SOD1 GO:0010628| positive regulation of gene expression RARG;RARA;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;JUN;RARA GO:0010033| response to organic substance JUN;CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0001774| microglial cell activation JUN;TRPV1 GO:0071277| cellular response to calcium ion ALOX15;JUN GO:0001525| angiogenesis JUN;PTGS2;CYP1B1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;RARA GO:0001889| liver development JUN;RARA;ACAT1;CYP1A1 GO:0006351| transcription, DNA-dependent RARB;PPARG;RARA;RARG;JUN GO:0043401| steroid hormone mediated signaling pathway PPARG;RARB;RARG;RARA GO:0042542| response to hydrogen peroxide GPX1;CAT;JUN;SOD1;TRPA1 GO:0009314| response to radiation CAT;PTGS2;OPRM1;JUN GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;RARB;CYP1B1;TRPV1;IDO1;JUN;PTGS2;SOD1;CNR1;RARG GO:0043524| negative regulation of neuron apoptosis JUN;SOD1 GO:0010629| negative regulation of gene expression OPRD1;RARA GO:0007565| female pregnancy RARA;IDO1 GO:0022008| neurogenesis RARB;DAGLA GO:0043010| camera-type eye development CYP1A1;RARG GO:0032870| cellular response to hormone stimulus CACNA1H;JUN GO:0007165| signal transduction CHRNA7;RARA;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;RARB;PPARG;GPR18;SMPD1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;JUN;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0071276| cellular response to cadmium ion SOD1;JUN;CYP1A2 GO:0048146| positive regulation of fibroblast proliferation JUN;PLA2G1B GO:0045740| positive regulation of DNA replication PLA2G1B;JUN GO:0008285| negative regulation of cell proliferation RARB;CYP1B1;PPARG;RARG;RARA;JUN;PTGS2;OPRM1 17401:[DB14011 DB02580] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02580|Pentaglyme PFN2;gpmA;purA common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;PFN2 GO:0030838| positive regulation of actin filament polymerization PFN2;ALOX15 17402:[DB14011 DB08617] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08617|4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE YARS common genes common pathways GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;YARS;PPARG;GPR18;SMPD1 GO:0006915| apoptotic process VDAC1;YARS;GPX1 17403:[DB14011 DB00119] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0051289| protein homotetramerization CAT;PKM;CRYZ;TRPA1;TRPV1;TRPM8 GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1;PKLR GO:0010629| negative regulation of gene expression PC;OPRD1 GO:0008152| metabolic process PKLR;SMPD1;PC;PDHB;ACAT1;PKM GO:0048148| behavioral response to cocaine HTR2A;ABAT GO:0006629| lipid metabolic process PC;NAAA;PTGS1;GPX1;SLC16A1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0045776| negative regulation of blood pressure CNR1;ABAT GO:0045471| response to ethanol ABAT;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0043403| skeletal muscle tissue regeneration GPX1;PKM GO:0001889| liver development CYP1A1;PKM;ACAT1 GO:0007584| response to nutrient PKM;CNR1;HMGCR;PKLR;PPARG GO:0032868| response to insulin stimulus CAT;AANAT;PKM;TRPV4 GO:0010226| response to lithium ion PTGS2;PKLR GO:0032869| cellular response to insulin stimulus PKLR;PLA2G1B;PPARG;PKM GO:0050796| regulation of insulin secretion SLC16A1;CNR1 GO:0035640| exploration behavior ABAT;HTR1A GO:0035094| response to nicotine CNR1;CHRNA7;ABAT GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABAT;ABCG2 GO:0032094| response to food CYP1A1;OPRM1;SLC16A1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;SLC16A1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1;PDHB GO:0033602| negative regulation of dopamine secretion ABAT;CNR1 GO:0007626| locomotory behavior ABAT;OPRM1;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT;PKM GO:0001666| response to hypoxia CYP1A1;PKLR;ABAT;CHRNA7;PKM;CAT GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PKM;PTGS2;CYP1A2;SOD1 GO:0051591| response to cAMP AANAT;PKLR GO:0055085| transmembrane transport SLC16A6;CACNA1G;SLC16A8;ABCC1;SLCO2A1;SLC16A3;TRPA1;TRPV1;TRPV4;CACNA1I;SLC16A5;VDAC1;ABCG2;TRPM8;SLC16A7;CACNA1H;TRPV3;SLC16A10;SLC16A4;TRPV2;SLC16A2;SLC16A1 GO:0042220| response to cocaine OPRM1;CNR1;ABAT;SMPD1 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;SLC16A1 GO:0031100| organ regeneration PPARG;PKM GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;AGXT2;OPRM1;PTGS2 GO:0007568| aging HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;ABAT GO:0006810| transport SLC16A2;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 17404:[DB14011 DB00212] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00212|Remikiren REN common genes common pathways GO:0048469| cell maturation PPARG;REN GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;REN GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1;REN GO:0001822| kidney development REN;CAT GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;REN;CYP1A1 GO:0042493| response to drug SMPD1;ABCC1;REN;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0010033| response to organic substance REN;TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0051591| response to cAMP AANAT;REN 17405:[DB14011 DB02623] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways GO:0007399| nervous system development CDC42;GLRB;SMPD1 GO:0045859| regulation of protein kinase activity CDC42;SOD1 GO:0010629| negative regulation of gene expression OPRD1;CDC42 GO:0001934| positive regulation of protein phosphorylation CHRNA7;CDC42 GO:0060047| heart contraction SOD1;GPX1;CDC42 GO:0033138| positive regulation of peptidyl-serine phosphorylation CDC42;PTGS2;OPRD1 GO:0045740| positive regulation of DNA replication PLA2G1B;CDC42 GO:0035722| interleukin-12-mediated signaling pathway CDC42;SOD1 GO:0046330| positive regulation of JNK cascade TRPV4;CDC42 GO:0007015| actin filament organization TRPV4;PLA2G1B;CDC42 GO:0043085| positive regulation of catalytic activity CDC42;SOD1 GO:0010628| positive regulation of gene expression CDC42;TRPV4 17406:[DB14011 DB01805] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0009235| cobalamin metabolic process PRSS1;ABCC1 GO:0007517| muscle organ development CACNA1H;ACHE GO:0007155| cell adhesion CYP1B1;ACHE GO:0043312| neutrophil degranulation PRSS2;CAT;ALOX5 GO:0008283| cell proliferation ACHE;HTR1A;GPX1;CYP1A1 GO:0007399| nervous system development ACHE;SMPD1;GLRB GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE 17407:[DB14011 DB02185] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02185|2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One LCTL common genes common pathways 17408:[DB14011 DB08187] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08187|METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0009611| response to wounding GPX1;F2;CYP1A1 17409:[DB14011 DB11201] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0098869| GSR;PTGS2;CAT;PTGS1;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| PTGS2;HMGCR GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS2;CNR2;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0010942| positive regulation of cell death PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;PTGS1;NAAA;GPX1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 17410:[DB14011 DB02418] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways 17411:[DB14011 DB11626] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11626|Tasonermin TNFRSF1A;TNFRSF1B common genes common pathways GO:0050729| positive regulation of inflammatory response TNFRSF1A;TRPV4 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CACNA1I;TNFRSF1A;PLA2G1B;PPARG;GPR18;SMPD1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TNFRSF1B;TRPV1;TNFRSF1A GO:0071260| cellular response to mechanical stimulus TNFRSF1A;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2;TNFRSF1A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process TNFRSF1B;GPX1;PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TNFRSF1A;TRPV1;IDO1;TNFRSF1B;ALOX15 GO:0016032| viral reproduction VDAC1;TNFRSF1A;HTR2A GO:0006955| immune response OPRD1;CNR2;TNFRSF1A;TNFRSF1B GO:0007568| aging CYP1A1;TNFRSF1B;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT GO:0071363| cellular response to growth factor stimulus TRPV1;TNFRSF1B;OPRD1;CAT GO:0006915| apoptotic process TNFRSF1B;VDAC1;TNFRSF1A;GPX1 GO:0032496| response to lipopolysaccharide TNFRSF1A;IDO1;TNFRSF1B;CYP1A1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;TNFRSF1B;TNFRSF1A GO:0043312| neutrophil degranulation ALOX5;CAT;TNFRSF1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;TNFRSF1A GO:0050728| negative regulation of inflammatory response CNR2;TNFRSF1A;TNFRSF1B 17412:[DB14011 DB04510] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04510|3-phospho-D-glyceric acid PGK1;PGAM2;TPI1 common genes common pathways GO:0008152| metabolic process TPI1;ACAT1;SMPD1;PGAM2 GO:0030855| epithelial cell differentiation VDAC1;PPARG;PGK1 GO:0007283| spermatogenesis PGAM2;SOD1;CNR1 GO:0071456| cellular response to hypoxia PGK1;SLC29A1;OPRD1;PTGS2 GO:0016525| negative regulation of angiogenesis PPARG;PGK1 17413:[DB14011 DB08632] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;HBB GO:0098869| HBA1;HBB;GSR;PTGS2;CAT;GPX1;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HBB;OPRM1;PTGS2 GO:0042744| hydrogen peroxide catabolic process HBB;HBA1;GPX1;CAT GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;HBA1;HBB;TRPA1 GO:0010942| positive regulation of cell death HBA1;HBB;PTGS2 GO:0051291| protein heterooligomerization GLRB;GLRA1;HBB;HBA1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;HBB 17414:[DB14011 DB09559] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09559|Necitumumab EGFR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;EGFR GO:0008284| positive regulation of cell proliferation EGFR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process EGFR;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0007623| circadian rhythm AANAT;EGFR GO:0042127| regulation of cell proliferation PTGS2;PTGS1;EGFR GO:0042060| wound healing EGFR;ALOX15;OPRM1 GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0030324| lung development EGFR;CYP1A2 GO:0071230| cellular response to amino acid stimulus GLRA1;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2;HMGCR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0006979| response to oxidative stress EGFR;PTGS2;SOD1;GPX1;PTGS1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;EGFR;PTGS2;OPRM1 GO:0033993| response to lipid PPARG;EGFR GO:0032355| response to estradiol stimulus EGFR;CAT;CYP1A2;PTGS2 GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;OPRD1;CAT GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;EGFR;TRPV4;ALOX15 GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0001503| ossification ALOX15;EGFR GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;PPARG GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0007166| cell surface receptor linked signaling pathway EGFR;TRPV1;TRPA1 GO:0051592| response to calcium ion AANAT;EGFR GO:0001889| liver development EGFR;CYP1A1;ACAT1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;EGFR GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2;HTR2A GO:0007165| signal transduction SMPD1;GPR18;PPARG;EGFR;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;EGFR GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;EGFR GO:0045740| positive regulation of DNA replication EGFR;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;EGFR GO:0032930| positive regulation of superoxide anion generation SOD1;EGFR GO:0008283| cell proliferation GPX1;HTR1A;EGFR;CYP1A1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;EGFR;TRPA1;PPARG;CYP1A1 17415:[DB14011 DB00775] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways GO:0001934| positive regulation of protein phosphorylation ITGB3;CHRNA7 GO:0016032| viral reproduction HTR2A;VDAC1;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;HTR2A GO:0046718| entry of virus into host cell ITGB3;HTR2A GO:0060055| angiogenesis involved in wound healing GPX1;ITGB3 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ITGB3 GO:0042060| wound healing ALOX15;ITGB3;OPRM1 GO:0002576| platelet degranulation ITGB3;SOD1;ITGA2B GO:0007155| cell adhesion ITGB3;CYP1B1;ITGA2B GO:0043277| apoptotic cell clearance ITGB3;ALOX15 17416:[DB14011 DB07297] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways GO:0016032| viral reproduction VDAC1;LCK;HTR2A GO:0030217| T cell differentiation LCK;GPR18 GO:0006919| activation of caspase activity LCK;PPARG GO:0042127| regulation of cell proliferation LCK;PTGS1;PTGS2 GO:0045087| innate immune response PPARG;LCK GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;LCK;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;LCK GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;LCK;HTR2A 17417:[DB14011 DB03680] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03680|Tartronate ME2;ME3 common genes common pathways GO:0022900| electron transport chain ME2;CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;ME3;CYP1A2;CAT;ME2;ALOX5;GPX1;PTGS1 GO:0009060| aerobic respiration ME3;CAT GO:0008152| metabolic process SMPD1;ME2;ACAT1 17418:[DB14011 DB00300] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1;ABCC4;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1 GO:0042493| response to drug NME1;CAT;ABCC4;SOD1;HTR2A;AK4;CYP1A2;PTGS2;ABCC2;ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent NME2;PPARG GO:0099133| ABCC1;ABCC2;ABCC10;ABCC4 GO:0010243| response to organic nitrogen TRPV1;PTGS2;ABCC4 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;ABCC4 GO:0071333| cellular response to glucose stimulus NME1;SLC29A1 GO:0032496| response to lipopolysaccharide ABCC2;IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0007155| cell adhesion NME2;CYP1B1 GO:0043312| neutrophil degranulation ALOX5;CAT;NME2 GO:0002576| platelet degranulation ABCC4;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NME2;PLA2G1B GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;NME2 GO:0055085| transmembrane transport TRPV2;ABCC4;ABCC10;SLC22A8;CACNA1H;TRPV3;ABCG2;TRPM8;ABCC2;TRPV1;VDAC1;TRPV4;ABCB1;CACNA1I;TRPA1;SLC22A6;CACNA1G;ABCC1 GO:0051591| response to cAMP NME1;AANAT GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0010033| response to organic substance ABCC4;SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCB1;ABCC2;ABCG2;ABCC1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0043388| positive regulation of DNA binding NME1;PPARG GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1;ABCC2 GO:0007565| female pregnancy IDO1;ABCC2 GO:0010629| negative regulation of gene expression OPRD1;NME1 GO:0007595| lactation NME1;SLC29A1 GO:0010976| positive regulation of neuron projection development CNR1;NME1 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;ABCC2 GO:0006351| transcription, DNA-dependent PPARG;NME2 GO:0001889| liver development CYP1A1;AK4;ACAT1 GO:0007399| nervous system development NME1;GLRB;SMPD1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCG2;ABCC1 GO:0015949| nucleobase-containing small molecule interconversion NME2;GSR;AK2;AK4;NME1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;GLRA3;SLC22A8;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0006139| nucleobase-containing compound metabolic process AK2;AK4;SLC29A1 GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;ABCC4;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;NME1;PPARG;CYP1B1 GO:0098656| SLC22A6;VDAC1;SLC22A8 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0007420| brain development ACAT1;AK4 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H 17419:[DB14011 DB06957] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06957|4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL HSP90AA1 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;HSP90AA1;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0009409| response to cold PPARG;HSP90AA1;TRPA1;TRPM8 GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;TRPV3;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;PTGS2;OPRM1 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 17420:[DB14011 DB01914] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0009750| response to fructose stimulus SLC2A5;PTGS2 GO:0070509| calcium ion import GCK;CACNA1H;CACNA1I;TRPV4;CACNA1G GO:0043312| neutrophil degranulation SLC2A5;CAT;ALOX5;SLC2A3 GO:0055085| transmembrane transport CACNA1H;SLC2A8;SLC2A1;TRPV3;SLC2A12;SLC2A9;SLC2A3;TRPV2;SLC2A6;SLC2A7;SLC5A1;SLC2A11;CACNA1G;ABCC1;SLC2A4;TRPA1;VDAC1;TRPV4;CACNA1I;SLC2A10;TRPV1;SLC5A2;SLC2A2;SLC2A5;ABCG2;TRPM8 GO:0071356| cellular response to tumor necrosis factor SLC2A4;TRPV1 GO:0015758| glucose transport PLA2G1B;SLC2A10;SLC2A2;SLC2A5;SLC2A4;SLC5A1;SLC2A1;SLC2A8;SLC2A9;SLC2A12;SLC2A3 GO:0071470| cellular response to osmotic stress TRPV4;SLC2A4 GO:0001666| response to hypoxia CYP1A1;SLC2A8;CHRNA7;CAT GO:0071456| cellular response to hypoxia SLC2A4;PTGS2;OPRD1;SLC29A1 GO:0006810| transport TRPV2;ABCC1;CACNA1I;TRPV1;SLC5A2;ABCG2 GO:0042593| glucose homeostasis CNR1;GCK;TRPV4;SLC2A4;PPARG GO:0007565| female pregnancy IDO1;SLC2A1 GO:0046415| urate metabolic process ABCG2;SLC2A9 GO:0050873| brown fat cell differentiation PTGS2;SLC2A4 GO:0045471| response to ethanol SLC2A4;CAT;CNR1;SOD1;OPRM1;HMGCR GO:0006970| response to osmotic stress SLC2A1;TRPV4 GO:0071260| cellular response to mechanical stimulus PTGS2;SLC2A1 GO:0008152| metabolic process GCK;ACAT1;SMPD1;HK1 GO:0032868| response to insulin stimulus TRPV4;SLC2A1;CAT;AANAT GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;SLC5A2;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;SLC5A1;CHRNA7 GO:0050796| regulation of insulin secretion SLC2A2;SLC2A1;GCK;CNR1 GO:0032869| cellular response to insulin stimulus SLC2A4;PPARG;PLA2G1B;GCK GO:0042908| xenobiotic transport SLC2A1;ABCC1;ABCG2 17421:[DB14011 DB04005] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways GO:0008152| metabolic process ACAT1;UCK2;SMPD1 17422:[DB14011 DB03376] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03376|'5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine EPRS common genes common pathways GO:0008152| metabolic process ACAT1;EPRS;SMPD1 17423:[DB14011 DB00063] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00063|Eptifibatide ITGB3 common genes common pathways GO:0046718| entry of virus into host cell ITGB3;HTR2A GO:0060055| angiogenesis involved in wound healing GPX1;ITGB3 GO:0010745| negative regulation of macrophage derived foam cell differentiation ITGB3;PPARG GO:0001934| positive regulation of protein phosphorylation ITGB3;CHRNA7 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;HTR2A GO:0016032| viral reproduction VDAC1;ITGB3;HTR2A GO:0043277| apoptotic cell clearance ITGB3;ALOX15 GO:0042060| wound healing ALOX15;ITGB3;OPRM1 GO:0007155| cell adhesion CYP1B1;ITGB3 GO:0002576| platelet degranulation ITGB3;SOD1 17424:[DB14011 DB04751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04751|Purvalanol A SRC;CSNK1G3;RPS6KA1 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0006915| apoptotic process VDAC1;RPS6KA1;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;SRC GO:0002376| immune system process SRC;IDO1 GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;SRC;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0016236| macroautophagy SRC;VDAC1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;SRC;GPX1;RPS6KA1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;SRC GO:0045944| positive regulation of transcription from RNA polymerase II promoter RPS6KA1;PPARG;PLA2G1B GO:0009615| response to virus CYP1A1;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0008283| cell proliferation CYP1A1;GPX1;SRC;HTR1A GO:0045453| bone resorption GPR55;SRC GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;CSNK1G3;SRC;GPR18;PPARG;SMPD1;RPS6KA1;PLA2G1B;CACNA1I GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process RPS6KA1;PTGS2;GPX1;SRC GO:0035556| intracellular signal transduction PLA2G1B;RPS6KA1;SRC GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SRC;SOD1;CNR1;PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;SRC;CAT;SOD1 GO:0051974| negative regulation of telomerase activity PPARG;SRC 17425:[DB14011 DB00149] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;BCAT1;HTR1A GO:0008152| metabolic process BCAT1;ACAT1;SMPD1;BCAT2 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;TRPV2;SLC16A2 GO:0055085| transmembrane transport SLC16A10;TRPV3;CACNA1H;SLC16A2;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1 GO:0006550| isoleucine catabolic process ACAT1;BCAT2 GO:0071230| cellular response to amino acid stimulus GLRA1;LARS GO:0032259| methylation LCMT1;CYP1A2;LCMT2 GO:0009083| branched chain family amino acid catabolic process BCAT2;ACAT1;BCAT1 17426:[DB14011 DB08251] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0009411| response to UV CAT;CASP3 GO:0006919| activation of caspase activity CASP3;PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CASP3;TRPA1;PPARG;CYP1A1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1;CASP3 GO:0042542| response to hydrogen peroxide GPX1;CASP3;CAT;SOD1;TRPA1 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0007507| heart development PPARG;CASP3 GO:0045165| cell fate commitment CASP3;PPARG GO:0007605| sensory perception of sound SOD1;GPX1;CASP3 GO:0009611| response to wounding CYP1A1;CASP3;GPX1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CASP3;CAT GO:0001666| response to hypoxia CHRNA7;CAT;CASP3;CYP1A1 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CASP3;PPARG;CYP1A1;TRPA1 GO:0043200| response to amino acid stimulus CASP3;GLRA3;GLRB GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0006915| apoptotic process VDAC1;GPX1;CASP3 GO:0046677| response to antibiotic CASP3;SOD1;CYP1A1 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;CASP3;GPX1;CAT GO:0042060| wound healing ALOX15;CASP3;OPRM1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CASP3;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0007611| learning or memory CNR1;CHRNA7;CASP3 GO:0035094| response to nicotine CASP3;CHRNA7;CNR1 GO:0042493| response to drug CASP3;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0071407| cellular response to organic cyclic compound CASP3;CYP1B1;CYP1A1 17427:[DB14011 DB01917] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRB1;GPR18;PPARG;ADRB2;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;SLC22A4;TRPV3;CACNA1H GO:0034220| ion transmembrane transport TRPA1;GLRA1;GLRB;TRPV1;GLRA3;SLC22A4;CHRNA7 GO:0002024| diet induced thermogenesis ADRB2;ADRB1;TRPV4;TRPV1 GO:0001822| kidney development CAT;ODC1 GO:0009615| response to virus CYP1A1;ODC1 GO:0008284| positive regulation of cell proliferation CHRNA7;ODC1;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ADRB2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0006641| triglyceride metabolic process CAT;GPX1;SLC22A4 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;ADRB1;CACNA1I;HTR1A;GPR55;HTR2A;CNR1;GPR12;ADRB2;OPRM1;CNR2;OPRD1;CHRNA7 GO:0045453| bone resorption ADRB2;GPR55 GO:0006811| ion transport SLC22A4;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8 GO:0050873| brown fat cell differentiation PTGS2;ADRB2;ADRB1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ADRB2 GO:0009409| response to cold ADRB2;TRPM8;ADRB1;PPARG;TRPA1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1;ADRB1 17428:[DB14011 DB06861] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06861|6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE F2 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0061844| F2;PLA2G1B 17429:[DB14011 DB03256] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways GO:0008152| metabolic process SMPD1;FTCD;ACAT1 17430:[DB14011 DB08486] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08486|Efaproxiral HBA1;HBB common genes common pathways GO:0010942| positive regulation of cell death PTGS2;HBB;HBA1 GO:0042542| response to hydrogen peroxide HBA1;HBB;TRPA1;SOD1;GPX1;CAT GO:0008217| regulation of blood pressure PPARG;HBB;PTGS1;SOD1;PTGS2 GO:0051291| protein heterooligomerization HBA1;GLRA1;HBB;GLRB GO:0043312| neutrophil degranulation HBB;CAT;ALOX5 GO:0042744| hydrogen peroxide catabolic process HBB;HBA1;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;TRPV1;PTGS2;OPRM1 GO:0098869| HBB;HBA1;GSR;PTGS2;CAT;GPX1;PTGS1 17431:[DB14011 DB08302] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes PPARG common pathways GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0055088| lipid homeostasis PPARG GO:0048469| cell maturation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG;GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4 GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0032526| response to retinoic acid PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0030308| negative regulation of cell growth PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0030224| monocyte differentiation PPARG GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG 17432:[DB14011 DB00943] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00943|Zalcitabine pol;DCK;ALB;SLC22A6;SLC22A7;SLC29A1;SLC29A2 common genes SLC29A1 common pathways GO:0008283| cell proliferation GPX1;HTR1A;SLC29A2;CYP1A1 GO:0006811| ion transport TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;SLC22A7;TRPV3;CACNA1H;GLRA3 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;DCK;SLC29A2 GO:0001895| retina homeostasis ALB;SOD1 GO:0098656| SLC22A7;SLC22A6;VDAC1 GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0015862| uridine transport SLC29A1 GO:0015858| nucleoside transport SLC29A2;SLC29A1 GO:0007595| lactation SLC29A1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:1901642| SLC29A1;SLC29A2 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC22A7;TRPV2;TRPA1;SLC22A6;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT 17433:[DB14011 DB07842] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes PPARG common pathways GO:0030224| monocyte differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG GO:0030308| negative regulation of cell growth PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042594| response to starvation PPARG;ACAT1 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1904706| PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0048469| cell maturation PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1;CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15 GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0006919| activation of caspase activity PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:1905461| PPARG GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG 17434:[DB14011 DB05308] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05308|ANX-510 TYMS common genes common pathways GO:0007568| aging TYMS;CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:0032259| methylation CYP1A2;TYMS GO:0034097| response to cytokine stimulus AANAT;PTGS2;TYMS GO:0007623| circadian rhythm AANAT;TYMS GO:0033189| response to vitamin A CAT;PPARG;CYP1A1;TYMS GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;PPARG;TYMS;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;TYMS;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;CYP1A1;TYMS GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;TYMS 17435:[DB14011 DB04764] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04764|[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE TPSB2 common genes common pathways 17436:[DB14011 DB08289] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08289|N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM-N-OXIDE IGKC common genes common pathways GO:0045087| innate immune response IGKC;PPARG GO:0002376| immune system process IDO1;IGKC GO:0006955| immune response OPRD1;CNR2;IGKC GO:0001895| retina homeostasis IGKC;SOD1 17437:[DB14011 DB00290] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0042493| response to drug ABCG2;BLMH;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0009636| response to toxin BLMH;CYP1A1;CYP1B1;GPX1;CAT 17438:[DB14011 DB07302] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes PPARG common pathways GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0030308| negative regulation of cell growth PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0030224| monocyte differentiation PPARG GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG 17439:[DB14011 DB02166] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02166|Propidium ACHE common genes common pathways GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0008283| cell proliferation CYP1A1;GPX1;ACHE;HTR1A GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development ACHE;CACNA1H GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization CAT;ACHE;HMGCR 17440:[DB14011 DB14597] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14597|Lanadelumab KLKB1 common genes common pathways GO:0006954| inflammatory response ALOX5;PTGS1;KLKB1;PTGS2;CNR2;ALOX15;IDO1;TRPV1 17441:[DB14011 DB07047] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0006810| transport TTR;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process TTR;NAPEPLD 17442:[DB14011 DB09517] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HBB GO:0098869| GSR;HBA1;HBB;CAT;GPX1;PTGS1;PTGS2 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;HBA1;HBB GO:0043312| neutrophil degranulation HBB;CAT;FTL;ALOX5 GO:0051291| protein heterooligomerization HBA1;GLRA1;HBB;GLRB GO:0008217| regulation of blood pressure PPARG;HBB;PTGS1;PTGS2;SOD1 GO:0042542| response to hydrogen peroxide HBA1;TRPA1;HBB;SOD1;GPX1;CAT GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;FTL 17443:[DB14011 DB07144] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;DHFR;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1 17444:[DB14011 DB04396] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04396|Thiodigalactoside NCAN;LGALS1 common genes common pathways GO:0048678| response to axon injury SOD1;LGALS1 GO:0045445| myoblast differentiation LGALS1;HMGCR GO:0007165| signal transduction CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;LGALS1;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0007155| cell adhesion CYP1B1;NCAN GO:0071333| cellular response to glucose stimulus SLC29A1;LGALS1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;LGALS1 GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;LGALS1;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0035900| response to isolation stress LGALS1;NAPEPLD GO:0010977| negative regulation of neuron projection development TRPV4;LGALS1 GO:0006915| apoptotic process VDAC1;GPX1;LGALS1 17445:[DB14011 DB07670] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;CYP2C18;CYP1A1;CYP2C9;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2;CYP2C18 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;CYP2C18;PTGS1;CYP3A4;CYP1A2;CYP3A7 17446:[DB14011 DB07643] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07643|5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 17447:[DB14011 DB08915] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08915|Aleglitazar PPARA;PPARG;NCOA1 common genes PPARG common pathways GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;PPARA GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PPARA;NCOA1 GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0032526| response to retinoic acid PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0042060| wound healing OPRM1;PPARA;ALOX15 GO:0030308| negative regulation of cell growth PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0050728| negative regulation of inflammatory response CNR2;PPARA GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0030224| monocyte differentiation PPARG GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;NCOA1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA;NCOA1 GO:0006631| fatty acid metabolic process ALOX15;PPARA;PTGS2;PTGS1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARG;AANAT;PPARA GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;PPARA GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0007507| heart development PPARG;PPARA GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PPARA;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9 GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;NCOA1;SOD1;CNR1 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0048469| cell maturation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent NCOA1;PPARA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARA;CNR1;NCOA1;HMGCR;PPARG;CYP1A1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0055088| lipid homeostasis PPARG GO:0032868| response to insulin stimulus PPARA;CAT;AANAT;TRPV4 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2 17448:[DB14011 DB06247] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06247|CX516 GRIA1 common genes common pathways GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GRIA1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;GRIA1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GRIA1 GO:0007268| synaptic transmission GLRA1;CACNA1G;GRIA1;GLRB;VDAC1;HTR2A;GLRA3;OPRD1;OPRM1 GO:0034220| ion transmembrane transport GRIA1;TRPV1;GLRB;GLRA1;TRPA1;CHRNA7;GLRA3 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;GRIA1;GLRA1;CHRNA7;SLC29A1;GLRA3;OPRM1 17449:[DB14011 DB07740] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways GO:0016126| sterol biosynthetic process HMGCR;HMGCS1 GO:0008152| metabolic process HMGCS1;SMPD1;ACAT1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;HMGCS1;CYP2C9;PPARG GO:0001889| liver development ACAT1;CYP1A1;HMGCS1 GO:0007420| brain development HMGCS1;ACAT1 GO:0009725| response to hormone stimulus ACAT1;HMGCS1 GO:0019216| regulation of lipid metabolic process HMGCS1;CYP1A1;PPARG;HMGCR;CNR1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;HMGCS1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0008203| cholesterol metabolic process HMGCS1;HMGCR;CAT GO:0033197| response to vitamin E HMGCS1;CAT GO:0006695| cholesterol biosynthetic process HMGCR;HMGCS1 GO:0071404| cellular response to low-density lipoprotein particle stimulus HMGCS1;PPARG GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;HMGCS1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;HMGCS1;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;HMGCS1 GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;HMGCS1;CYP1A1;CYP2C9;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;HMGCS1;SOD1;PTGS2;CYP1A2 GO:0045540| regulation of cholesterol biosynthetic process HMGCS1;HMGCR GO:0008299| isoprenoid biosynthetic process HMGCR;HMGCS1 17450:[DB14011 DB02404] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion CYP1B1;ACHE GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA 17451:[DB14011 DB04469] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;PDE4D;OPRD1 GO:0006939| smooth muscle contraction HTR2A;PDE4D GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0007568| aging HMGCR;PDE4D;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CAT;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PDE4D;PPARG;GPR18 GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B 17452:[DB14011 DB00595] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00595|Oxytetracycline rpsI;rpsD;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0055085| transmembrane transport ABCC1;SLC22A6;CACNA1G;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2;TRPV3;CACNA1H;SLC22A8;TRPV2;SLC22A11;SLC22A7 GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;SLC22A7;CHRNA7;SLC22A11;CACNA1H;TRPV3;GLRA3;SLC22A8 GO:0098656| SLC22A7;SLC22A8;VDAC1;SLC22A6 GO:0046415| urate metabolic process SLC22A11;ABCG2 17453:[DB14011 DB06530] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06530|Resiquimod TLR7;TLR8 common genes common pathways GO:0002376| immune system process TLR8;IDO1;TLR7 GO:0009615| response to virus TLR8;CYP1A1 GO:0045087| innate immune response TLR8;PPARG;TLR7 GO:0050729| positive regulation of inflammatory response TLR7;TRPV4 GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;TLR8;PLA2G1B;CACNA1I;TLR7;GPR18;PPARG;SMPD1 GO:0001774| microglial cell activation TLR8;TRPV1;TLR7 GO:0071260| cellular response to mechanical stimulus TLR8;TLR7;PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;TLR8;IDO1;TLR7 GO:0006955| immune response CNR2;OPRD1;TLR7 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;TLR8 17454:[DB14011 DB06607] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways GO:0045087| innate immune response PPARG;FCGR1A GO:0043312| neutrophil degranulation FCGR2A;FCGR3B;ALOX5;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EPCAM;PPARG GO:0008284| positive regulation of cell proliferation EPCAM;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CD3E;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0051260| protein homooligomerization GLRA1;CD3E;GLRA3;ACAT1 GO:0002376| immune system process FCGR2A;FCGR1A;IDO1;CD3E GO:0001657| ureteric bud development CAT;EPCAM GO:0010628| positive regulation of gene expression TRPV4;CD3E GO:0007166| cell surface receptor linked signaling pathway TRPV1;CD3E;TRPA1 GO:0010629| negative regulation of gene expression OPRD1;CD3E GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD3E GO:0006955| immune response FCGR1A;FCGR3B;OPRD1;FCGR3A;CNR2 GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;FCGR1A;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;CD3E 17455:[DB14011 DB08687] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08687|FG-2216 EGLN1;HIF1A common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;HIF1A GO:0006355| regulation of transcription, DNA-dependent HIF1A;PPARG GO:0055114| oxidation-reduction process GSR;IDO1;CYP2C19;CYP2D6;EGLN1;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0061298| retina vasculature development in camera-type eye CYP1B1;HIF1A GO:0042127| regulation of cell proliferation PTGS2;HIF1A;PTGS1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;HIF1A;SOD1;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGLN1;PLA2G1B;PPARG;HIF1A GO:0045766| positive regulation of angiogenesis CHRNA7;HIF1A;CYP1B1 GO:0010628| positive regulation of gene expression TRPV4;HIF1A GO:0001666| response to hypoxia CAT;CHRNA7;HIF1A;EGLN1;CYP1A1 GO:0046716| muscle cell homeostasis SOD1;HIF1A GO:0048514| blood vessel morphogenesis CYP1B1;HIF1A GO:0010468| regulation of gene expression HIF1A;CYP1A2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;HIF1A;SLC29A1 GO:1901214| CHRNA7;EGLN1 GO:0042593| glucose homeostasis TRPV4;PPARG;HIF1A;CNR1 GO:0043524| negative regulation of neuron apoptosis SOD1;HIF1A GO:0010629| negative regulation of gene expression HIF1A;OPRD1 GO:0008542| visual learning HIF1A;HMGCR GO:0006879| cellular iron ion homeostasis ABCG2;EGLN1;HIF1A;SOD1 GO:0007595| lactation HIF1A;SLC29A1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;HIF1A;PTGS2 GO:0006351| transcription, DNA-dependent HIF1A;PPARG GO:0045821| positive regulation of glycolysis HTR2A;HIF1A GO:0001525| angiogenesis CYP1B1;PTGS2;HIF1A GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;HIF1A GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;HIF1A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B 17456:[DB14011 DB00122] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00122|Choline PCYT1B;ACHE;PCYT1A;PLD2;BCHE;PLD1;PHOSPHO1;CHRNA7;CEPT1;CHKB;CHAT;CHKA;CHDH;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC44A1;SLC44A4;SLC44A2;SLC44A3;SLC5A7 common genes CHRNA7 common pathways GO:0007612| learning PTGS2;VDAC1;BCHE GO:0007611| learning or memory CHRNA7;CNR1 GO:1905144| CHRNA7 GO:0007614| short-term memory CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;GLRA1;GLRB;TRPV1 GO:0007269| neurotransmitter secretion SLC22A2;SLC5A7;CHAT;NAAA GO:1905906| CHRNA7 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0006654| phosphatidic acid biosynthetic process PLD1;PLD2;PLA2G1B GO:0007155| cell adhesion CYP1B1;ACHE GO:0043312| neutrophil degranulation SLC44A2;ALOX5;PLD1;CAT GO:0042493| response to drug PPARG;CYP1A1;TRPA1;BCHE;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0007517| muscle organ development CACNA1H;ACHE GO:0050808| synapse organization CHRNA7 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CHDH;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0050893| sensory processing CHRNA7 GO:0035094| response to nicotine CNR1;CHRNA7 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0098815| CHRNA7 GO:0051260| protein homooligomerization SLC22A1;GLRA1;GLRA3;ACAT1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:1901214| CHRNA7 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CHRNA7;GPR12;HTR2A GO:0095500| CHRNA7 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;SLC22A4;GLRA3;CHRNA7 GO:0016042| lipid catabolic process DAGLA;PLD2;PLA2G1B;PLD1;NAPEPLD GO:1905920| CHRNA7 GO:0055085| transmembrane transport SLC22A4;TRPV3;SLC22A3;CACNA1H;SLC44A3;SLC22A5;TRPV2;SLC44A4;ABCC1;SLC22A1;CACNA1G;TRPA1;SLC44A2;TRPV4;CACNA1I;VDAC1;SLC44A1;SLC5A7;TRPV1;SLC22A2;TRPM8;ABCG2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7 GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0001541| ovarian follicle development SOD1;PCYT1B GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0006646| phosphatidylethanolamine biosynthetic process PHOSPHO1;CHKA;CEPT1;CHKB;ALOX15 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0007283| spermatogenesis SOD1;CNR1;PCYT1B GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:1902991| CHRNA7 GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0042136| neurotransmitter biosynthetic process ACHE;CHAT;SLC5A7;SLC22A2;DAGLA GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0006629| lipid metabolic process PCYT1A;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;PLD2;CHKB;PCYT1B;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;CHKA;PTGS1;NAAA;GPX1;CEPT1;PLD1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902004| CHRNA7 GO:1902430| CHRNA7 GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G;CHRNA7;TRPV2;TRPV3;CACNA1H GO:0050890| cognition CHRNA7 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0097061| dendritic spine organization CHRNA7 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0070588| calcium ion transmembrane transport TRPV3;CACNA1H;OPRM1;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8 GO:1900273| CHRNA7 GO:1904645| CHRNA7 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;SLC44A2;GPR55;HTR1A;CHKA;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0006641| triglyceride metabolic process GPX1;CAT;SLC22A4 GO:0006811| ion transport GLRA3;SLC22A5;CACNA1H;SLC22A3;TRPV3;SLC22A4;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;SLC22A1;TRPM8;SLC22A2;TRPV1;SLC5A7;CACNA1I;TRPV4;GLRB;VDAC1 GO:0008283| cell proliferation HTR1A;ACHE;GPX1;CYP1A1 GO:0009636| response to toxin CYP1A1;CYP1B1;CHKA;CAT;GPX1 GO:0006855| drug transmembrane transport SLC22A2;ABCG2;SLC22A1;ABCC1;SLC22A5;SLC22A3 GO:0006812| cation transport SLC22A1;TRPM8;SLC22A2 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;BCHE 17457:[DB14011 DB04801] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04801|cis-Vaccenic acid PPARD common genes common pathways GO:0007566| embryo implantation PPARD;PTGS2;SOD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0008283| cell proliferation PPARD;HTR1A;GPX1;CYP1A1 GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD;HTR2A GO:0001890| placenta development SOD1;PPARD;PPARG GO:0060612| adipose tissue development PPARD;ACAT1 GO:0019395| fatty acid oxidation PPARG;PPARD GO:0014823| response to activity CAT;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;PPARD GO:0006351| transcription, DNA-dependent PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARG GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0007507| heart development PPARD;PPARG GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG;GPX1;NAAA;PTGS1;HMGCR;PPARD;CYP1A2;PTGS2;NAPEPLD;CYP3A4 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PPARD;PTGS2 GO:0046697| decidualization PPARD;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0006915| apoptotic process GPX1;PPARD;VDAC1 GO:0010628| positive regulation of gene expression TRPV4;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG GO:0015758| glucose transport PPARD;PLA2G1B GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;PTGS2;CYP1A2;PPARD GO:0042127| regulation of cell proliferation PTGS1;PPARD;PTGS2 GO:0042060| wound healing ALOX15;OPRM1;PPARD GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;PPARD;HMGCR GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;PPARD;SOD1;GPX1;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD GO:0050728| negative regulation of inflammatory response PPARD;CNR2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;PPARG GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0033189| response to vitamin A CYP1A1;PPARG;PPARD;CAT 17458:[DB14011 DB05391] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05391|liposomal prostaglandin E1 GP1BA common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;GP1BA;TRPV1 GO:0007155| cell adhesion CYP1B1;GP1BA 17459:[DB14011 DB08192] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08192|2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE SRC common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0042542| response to hydrogen peroxide CAT;GPX1;SRC;SOD1;TRPA1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1;SRC GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0008283| cell proliferation CYP1A1;GPX1;SRC;HTR1A GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;SRC GO:0070542| response to fatty acid CAT;SRC;PTGS2 GO:0045453| bone resorption SRC;GPR55 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;SRC;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response PPARG;SRC GO:0009615| response to virus CYP1A1;SRC GO:0043066| negative regulation of apoptotic process CAT;GPX1;SRC;SOD1;PTGS2;HMGCR GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1 GO:0002376| immune system process IDO1;SRC GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 17460:[DB14011 DB09421] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09421|Protirelin TRHR common genes common pathways GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;TRHR;GPR18;PLA2G1B;CACNA1I GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;TRHR;PPARG;GPR18 17461:[DB14011 DB07652] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07652|1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE POLK;rnhA common genes common pathways GO:0034644| cellular response to UV POLK;PTGS2 17462:[DB14011 DB08561] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08561|BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;ALOX15;MMP13 17463:[DB14011 DB00046] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways GO:0045740| positive regulation of DNA replication IGF1R;INSR;PLA2G1B GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;IGF1R GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;IGF1R;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0007613| memory INSR;CHRNA7;PTGS2;HTR2A;CNR1 GO:0032869| cellular response to insulin stimulus INSR;PPARG;PLA2G1B GO:0006955| immune response OPRD1;IGF1R;CNR2 GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 GO:0035556| intracellular signal transduction INSR;PLA2G1B GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0051262| protein tetramerization IGF1R;HMGCR;CAT GO:0000187| activation of MAPK activity INSR;PLA2G1B;SOD1;CHRNA7 GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;INSR;OPRM1;PTGS2 GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;INSR;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0006355| regulation of transcription, DNA-dependent PPARG;INSR GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;IGF1R;HTR2A;HTR1A;INSR GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;IGF1R;PTGS2 GO:0007612| learning PTGS2;VDAC1;INSR 17464:[DB14011 DB13783] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes PTGS1;PTGS2;ABCC1 common pathways GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0098869| PTGS2;CAT;PTGS1;GPX1;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0006810| transport ABCC1;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0007568| aging CYP1A1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0008202| steroid metabolic process UGT2B7;CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:1902219| PTGS2 GO:0009235| cobalamin metabolic process ABCC1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0060326| cell chemotaxis ABCC1 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0099133| ABCC1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0006691| leukotriene metabolic process ALOX5;ALOX15;ABCC1 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning PTGS2;VDAC1 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0015889| cobalamin transport ABCC1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;UGT2B7;NAAA;PTGS1;GPX1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B GO:0034775| glutathione transmembrane transport ABCC1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:1990776| PTGS2 GO:0008152| metabolic process ACAT1;UGT2B7;SMPD1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;TRPA1;TRPV1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 17465:[DB14011 DB00800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0042053| regulation of dopamine metabolic process HTR1A;DRD1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1D;ADRA1A GO:0001662| behavioral fear response VDAC1;DRD1;HTR1A GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0008285| negative regulation of cell proliferation CYP1B1;ADRA1A;PPARG;OPRM1;PTGS2 GO:0008283| cell proliferation HTR1A;ADRA1B;GPX1;CYP1A1;ADRA1D GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1 GO:0045777| positive regulation of blood pressure ADRA2B;CNR1 GO:0006939| smooth muscle contraction ADRA1A;HTR2A GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;ADRA2C;HTR2A;ADRA1A;ADRA1D GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H GO:0009725| response to hormone stimulus ADRA1A;ACAT1 GO:0007165| signal transduction CHRNA7;DRD1;ADRA1B;DRD5;GPR12;CNR1;HTR2A;ADRA2B;HTR1A;GPR55;ADRA2C;OPRD1;OPRM1;CNR2;ADRA2A;PLA2G1B;CACNA1I;ADRA1A;GPR18;PPARG;SMPD1;ADRA1D GO:0072593| reactive oxygen species metabolic process SOD1;DRD5 GO:0001975| response to amphetamine DRD5;DRD1;CNR2;SOD1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;OPRM1;HTR2A;TRPV4;ADRA1A;TRPV1;ADRA1D GO:0050796| regulation of insulin secretion ADRA2A;ADRA2C;CNR1 GO:0007613| memory HTR2A;CNR1;PTGS2;DRD1;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADRA2A GO:0019226| transmission of nerve impulse DRD5;DRD1;SOD1 GO:0008542| visual learning DRD1;HMGCR GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;DRD5;OPRD1;OPRM1;GLRA3;HTR2A GO:0007565| female pregnancy IDO1;ADRA2B;ADRA2C GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRA1B;ADRA1D GO:0001659| temperature homeostasis HTR2A;GPX1;DRD1;TRPV1 GO:0048148| behavioral response to cocaine HTR2A;DRD1 GO:0035556| intracellular signal transduction ADRA1B;PLA2G1B;ADRA1A GO:0045776| negative regulation of blood pressure DRD5;CNR1 GO:0019228| regulation of action potential in neuron CACNA1G;CACNA1I;CACNA1H;DRD1 GO:0010628| positive regulation of gene expression TRPV4;DRD1 GO:0007202| activation of phospholipase C activity ADRA1A;GPR55;HTR2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;CNR1;OPRM1;CNR2;OPRD1 GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;DRD1;GPR18 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;ADRA1A;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0006915| apoptotic process GPX1;VDAC1;ADRA1A GO:0042220| response to cocaine CNR1;OPRM1;DRD1;DRD5;SMPD1 GO:0000187| activation of MAPK activity CHRNA7;ADRA2B;SOD1;PLA2G1B GO:0042593| glucose homeostasis PPARG;TRPV4;ADRA2A;CNR1;ADRA1B GO:0006936| muscle contraction GLRA1;DRD1;CACNA1H GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;DRD5;HTR2A;GPR12 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;ADRA2C;HTR2A;GPR12;CNR1;ADRA2B;DRD5;ADRA1B;DRD1;ADRA1D;PPARG;GPR18;ADRA1A;ADRA2A GO:0007568| aging ADRA1A;CYP1A1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;DRD1;CAT;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;ADRA1A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0007626| locomotory behavior SOD1;OPRM1;DRD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD1;DRD5 GO:0042311| vasodilation DRD1;GPX1 GO:0007628| adult walking behavior GLRB;GLRA1;DRD1 GO:0007612| learning VDAC1;DRD5;DRD1;PTGS2 GO:0042060| wound healing OPRM1;DRD5;ALOX15 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;OPRM1;OPRD1;HTR2A;ADRA1A;ADRA1D GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A 17466:[DB14011 DB07229] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07229|3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-5-METHOXY-1,1'-BIPHENYL-2-OLATE PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 17467:[DB14011 DB07282] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0042572| retinol metabolic process CYP1B1;TTR GO:0006810| transport TTR;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0043312| neutrophil degranulation ALOX5;CAT;TTR 17468:[DB14011 DB02427] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;DHFR;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT 17469:[DB14011 DB05289] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05289|Tarenflurbil IKBKG common genes common pathways GO:0006915| apoptotic process IKBKG;VDAC1;GPX1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;IKBKG GO:0006355| regulation of transcription, DNA-dependent PPARG;IKBKG GO:0045087| innate immune response PPARG;IKBKG GO:0009615| response to virus CYP1A1;IKBKG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;IKBKG GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;TRPV1;IKBKG;ALOX15;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;IKBKG GO:0006955| immune response IKBKG;CNR2;OPRD1 GO:0016032| viral reproduction HTR2A;IKBKG;VDAC1 GO:0006351| transcription, DNA-dependent IKBKG;PPARG 17470:[DB14011 DB00168] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes TRPV1 common pathways GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPV1;TRPA1 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0048265| response to pain TRPV1;TRPA1 GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0001660| fever generation TRPV1 GO:0002024| diet induced thermogenesis TRPV1;TRPV4 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0034220| ion transmembrane transport CHRNA7;GLRA3;TRPV1;GLRB;TRPA1;GLRA1 GO:0071502| cellular response to temperature stimulus TRPV1 GO:0055085| transmembrane transport TRPV2;SLC22A11;CACNA1H;TRPV3;SLC22A8;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;SLC22A6;ABCC1;TRPA1 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway TAS1R2;GPR18;PPARG;OPRD1;CNR2;OPRM1;TAS1R3;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0071468| cellular response to acidity TRPV1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;HTR2A GO:0006810| transport ABCC1;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0007635| chemosensory behavior TRPV1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0098703| TRPV1 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;TRPV1;ALOX15;IDO1 GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPV1;TRPM8;CAT GO:0009408| response to heat TRPV1;TRPV2;TRPV3;SOD1 GO:0014047| glutamate secretion TRPV1 GO:0009268| response to pH TRPV1 GO:0002790| peptide secretion TRPV1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0048266| behavioral response to pain TRPV1 GO:0001774| microglial cell activation TRPV1 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1;TRPV1;TRPA1 GO:1901594| TRPV1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1 GO:0071312| cellular response to alkaloid TRPV1 GO:0001659| temperature homeostasis HTR2A;GPX1;TRPV1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0050955| thermoception TRPM8;TRPV1;TRPA1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1;CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 GO:1990090| TRPV1 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport SLC22A8;GLRA3;CACNA1H;TRPV3;CHRNA7;SLC22A11;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB GO:0050896| response to stimulus TRPM8;TRPA1;TAS1R2;TAS1R3 GO:0098656| SLC22A6;VDAC1;SLC22A8 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1 GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1H;TRPV3;TRPV2;CHRNA7;CACNA1G;TRPA1;CACNA1I;TRPV4;TRPV1;TRPM8 GO:0065009| regulation of molecular function TRPV1 GO:0007165| signal transduction OPRD1;OPRM1;TAS1R3;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;TAS1R2;GPR18;PPARG;PLA2G1B;CACNA1I 17471:[DB14011 DB07873] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process GGPS1;HMGCR GO:0045540| regulation of cholesterol biosynthetic process GGPS1;HMGCR GO:0008299| isoprenoid biosynthetic process HMGCR;GGPS1 17472:[DB14011 DB12307] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A7;CYP3A4;CYP3A5 common pathways GO:0043066| negative regulation of apoptotic process KDR;HGF;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0002576| platelet degranulation SOD1;HGF GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;HGF GO:0008284| positive regulation of cell proliferation KDR;HGF;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0050728| negative regulation of inflammatory response HGF;CNR2 GO:0060326| cell chemotaxis HGF;ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;HGF GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;CYP3A43;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0031100| organ regeneration HGF;PPARG GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP2C9;CYP1A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade HGF;KDR;CAT GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP1A1 GO:0000187| activation of MAPK activity HGF;PLA2G1B;CHRNA7;SOD1 GO:0045766| positive regulation of angiogenesis CHRNA7;KDR;CYP1B1;HGF GO:0036378| CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;KDR GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;GPX1;NAAA;PTGS1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0001889| liver development ACAT1;CYP1A1;HGF GO:0001525| angiogenesis CYP1B1;KDR;PTGS2 GO:0016032| viral reproduction HTR2A;KDR;VDAC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;HGF GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process HGF;PTGS2;GPX1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0008209| androgen metabolic process CYP3A4 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0090201| negative regulation of release of cytochrome c from mitochondria HGF;GPX1 GO:1902042| GPX1;HGF GO:0051450| myoblast proliferation GPX1;HGF GO:0008283| cell proliferation GPX1;HTR1A;HGF;CYP1A1 17473:[DB14011 DB05262] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05262|Oxypurinol XDH common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;HMGCR;XDH;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT GO:0022900| electron transport chain XDH;CYP1A2;GSR;IDO1 GO:0006919| activation of caspase activity PPARG;XDH GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0010629| negative regulation of gene expression OPRD1;XDH GO:0007595| lactation XDH;SLC29A1 17474:[DB14011 DB12436] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12436|Vofopitant TACR1 common genes common pathways GO:0009408| response to heat TRPV1;SOD1;TRPV3;TACR1;TRPV2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PTGS1;ALOX5;PTGS2;CNR2;TACR1 GO:0007268| synaptic transmission GLRB;VDAC1;GLRA1;CACNA1G;HTR2A;GLRA3;OPRM1;TACR1;OPRD1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRD1;TACR1;CNR2;PTGS2;OPRM1;HTR2A;CNR1 GO:0045471| response to ethanol TACR1;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0048266| behavioral response to pain TRPV1;TACR1 GO:0008217| regulation of blood pressure PPARG;SOD1;TACR1;PTGS2;PTGS1 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0045777| positive regulation of blood pressure CNR1;TACR1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;TACR1;PTGS2;PPARG;CYP1A1;TRPA1 GO:0042755| eating behavior TACR1;OPRM1;OPRD1 GO:0007165| signal transduction CNR2;TACR1;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0009725| response to hormone stimulus TACR1;ACAT1 GO:0045907| positive regulation of vasoconstriction HTR2A;TACR1;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;OPRM1;TACR1 GO:0043117| positive regulation of vascular permeability TACR1;TRPV4 GO:0060083| smooth muscle contraction involved in micturition TACR1;TRPV1 GO:0043278| response to morphine CNR1;OPRM1;TACR1 GO:0048265| response to pain TACR1;TRPV1;TRPA1 GO:0035094| response to nicotine TACR1;CNR1;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;TACR1;HTR2A GO:0007611| learning or memory CNR1;TACR1;CHRNA7 GO:0010193| response to ozone TACR1;CAT GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;TACR1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;TACR1;OPRD1 17475:[DB14011 DB06920] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06920|Eribaxaban F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 17476:[DB14011 DB06953] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06953|2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE FNTA;FNTB common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;PTGS2;FNTB 17477:[DB14011 DB04105] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04105|N-Heptylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;ADH1B 17478:[DB14011 DB05407] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05407|TBC-3711 EDN1 common genes common pathways GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;EDN1;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0030593| neutrophil chemotaxis EDN1;PLA2G1B GO:0035094| response to nicotine EDN1;CHRNA7;CNR1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;EDN1 GO:0014824| artery smooth muscle contraction EDN1;HTR2A GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;EDN1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDN1;TRPV4;TRPV1;PPARG GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;EDN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;EDN1;PLA2G1B GO:0043200| response to amino acid stimulus GLRB;EDN1;GLRA3 GO:0043406| positive regulation of MAP kinase activity HTR2A;EDN1 GO:0071356| cellular response to tumor necrosis factor EDN1;TRPV1 GO:0015758| glucose transport PLA2G1B;EDN1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;EDN1;GPR55 GO:0001666| response to hypoxia CAT;CHRNA7;EDN1;CYP1A1 GO:0010193| response to ozone EDN1;CAT GO:0071456| cellular response to hypoxia EDN1;PTGS2;OPRD1;SLC29A1 GO:0048514| blood vessel morphogenesis EDN1;CYP1B1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PPARG;GPR18;EDN1 GO:0042554| superoxide anion generation EDN1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;EDN1;TRPV1 GO:0060137| maternal process involved in parturition CYP1A1;EDN1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;EDN1 GO:0007166| cell surface receptor linked signaling pathway EDN1;TRPV1;TRPA1 GO:0071277| cellular response to calcium ion EDN1;ALOX15 GO:0019233| sensory perception of pain TRPA1;EDN1;TRPV1;CNR1;HTR2A;OPRD1;OPRM1;PTGS2;CNR2 GO:0007507| heart development PPARG;EDN1 GO:0035556| intracellular signal transduction PLA2G1B;EDN1 GO:0042310| vasoconstriction HTR1A;EDN1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1;EDN1 GO:0051930| regulation of sensory perception of pain EDN1;OPRM1;OPRD1 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;EDN1 GO:0014823| response to activity CAT;EDN1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;EDN1 GO:0007204| elevation of cytosolic calcium ion concentration EDN1;TRPV1;TRPV4;HTR2A;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;EDN1 GO:0014065| phosphatidylinositol 3-kinase cascade EDN1;HTR2A 17479:[DB14011 DB12555] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12555|Nelotanserin HTR2A common genes HTR2A common pathways GO:0043267| negative regulation of potassium ion transport HTR2A GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0046883| regulation of hormone secretion HTR1A;HTR2A GO:0046718| entry of virus into host cell HTR2A GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A GO:0006939| smooth muscle contraction HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007610| behavior HTR2A;HTR1A GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain TRPA1;HTR2A GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GLRA1;CACNA1G;VDAC1;GLRB GO:0016032| viral reproduction VDAC1;HTR2A GO:0033674| positive regulation of kinase activity HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0045821| positive regulation of glycolysis HTR2A GO:0030431| sleep HTR2A;SLC29A1;CACNA1I GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPV1;TRPA1 GO:0001659| temperature homeostasis TRPV1;HTR2A;GPX1 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A GO:0048148| behavioral response to cocaine HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;ALOX15 GO:0008219| cell death HTR2A GO:0007202| activation of phospholipase C activity HTR2A;GPR55 GO:0043406| positive regulation of MAP kinase activity HTR2A GO:0014059| regulation of dopamine secretion HTR2A GO:0051209| release of sequestered calcium ion into cytosol TRPV1;TRPA1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;GPR18;PPARG GO:0007568| aging CYP1A1;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPM8;TRPV4 GO:0007210| serotonin receptor signaling pathway HTR1A;HTR2A GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0044380| protein localization to cytoskeleton HTR2A GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2A GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A GO:0014824| artery smooth muscle contraction HTR2A GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0050795| regulation of behavior HTR1A;HTR2A 17480:[DB14011 DB06741] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06741|Gavestinel GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;UGT1A1;UGT1A3;UGT1A9;UGT2B4 common genes common pathways GO:0030431| sleep CACNA1I;HTR2A;SLC29A1;GRIN2A GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;PTGS2;CNR2;GRIN1;OPRM1;OPRD1;GRIN2A GO:0001889| liver development ACAT1;UGT1A1;CYP1A1 GO:0045471| response to ethanol GRIN2A;CAT;SOD1;CNR1;GRIN2B;HMGCR;OPRM1;GRIN1;GRIN3A;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;UGT1A1;CYP1A1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0060078| regulation of postsynaptic membrane potential GRIN2A;CHRNA7 GO:0008152| metabolic process UGT1A3;ACAT1;UGT2B4;UGT1A1;UGT1A9;SMPD1 GO:0006805| xenobiotic metabolic process UGT2B4;CYP2C9;UGT1A9;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0042428| serotonin metabolic process GRIN2A;HTR1A GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;GRIN1;PTGS2;SOD1;CNR1;GRIN2A GO:0007268| synaptic transmission GRIN2A;HTR2A;GLRA3;GRIN2B;OPRD1;OPRM1;GLRB;VDAC1;GLRA1;CACNA1G GO:0043524| negative regulation of neuron apoptosis SOD1;GRIN1 GO:0008542| visual learning GRIN1;HMGCR;GRIN2A GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:0006816| calcium ion transport GRIN3A;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;CACNA1H;GRIN1;TRPV3;CHRNA7;GRIN2A;TRPV2 GO:0001964| startle response GRIN1;GRIN2D;GRIN2A;GLRA1;GLRB GO:0022008| neurogenesis GRIN2A;DAGLA GO:0007613| memory GRIN2A;CHRNA7;GRIN1;PTGS2;CNR1;HTR2A GO:0043576| regulation of respiratory gaseous exchange GLRA1;GRIN1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;UGT1A9;CNR1;HMGCR GO:0001975| response to amphetamine SOD1;CNR2;GRIN1;GRIN2A GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0065009| regulation of molecular function GRIN2A;GRIN2B;GRIN2D;GRIN1;TRPV1;GRIN2C GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:1900273| GRIN2A;CHRNA7 GO:0070588| calcium ion transmembrane transport TRPV1;TRPV4;GRIN3B;CACNA1I;TRPM8;CACNA1G;TRPA1;GRIN3A;TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1 GO:0008344| adult locomotory behavior OPRD1;GRIN2D;GRIN1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;UGT1A1;TRPA1;PPARG;CYP1A1 GO:0006811| ion transport GRIN2A;CHRNA7;TRPV2;GLRA3;GRIN2B;TRPV3;GRIN2D;GRIN1;CACNA1H;TRPM8;GRIN3B;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPA1;GLRA1;GRIN3A;CACNA1G;GRIN2C GO:0051930| regulation of sensory perception of pain OPRM1;GRIN2D;OPRD1;GRIN2A GO:0006812| cation transport GRIN1;TRPM8 GO:0007584| response to nutrient UGT1A1;PPARG;HMGCR;CNR1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2A;CHRNA7;SLC29A1;GRIN2B;GLRA3;GRIN2D;GRIN1;OPRM1;GRIN3B;GLRB;TRPV1;GRIN3A;GLRA1;GRIN2C GO:0043523| regulation of neuron apoptosis GRIN1;GPX1 GO:0007611| learning or memory GRIN2A;CHRNA7;GRIN1;GRIN2B;CNR1 GO:0007612| learning VDAC1;GRIN2A;PTGS2;GRIN1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;IDO1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0010524| positive regulation of calcium ion transport into cytosol GRIN1;PLA2G1B GO:0042594| response to starvation ACAT1;PPARG;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;GRIN1 GO:0050905| neuromuscular process GLRA1;GLRB;GRIN1 GO:0042493| response to drug CAT;GRIN2A;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;UGT1A1;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0043278| response to morphine OPRM1;GRIN1;CNR1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0006810| transport CACNA1I;TRPV1;ABCG2;GRIN2C;ABCC1;TRPV2;GRIN2A;GRIN2B GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;UGT1A1;CYP1A1;CYP2C9;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0009611| response to wounding GRIN2A;GPX1;CYP1A1;GRIN2C GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4;UGT1A3 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;HTR2A;GPR12;GRIN1;CHRNA7 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;GRIN2C;GRIN2A;GRIN1;CACNA1H GO:0031100| organ regeneration UGT1A1;PPARG GO:0034220| ion transmembrane transport CHRNA7;GLRA3;TRPV1;GLRB;GRIN3B;TRPA1;GLRA1;GRIN3A GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1;UGT1A1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential GRIN1;CHRNA7 17481:[DB14011 DB08655] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;CREBBP GO:0016032| viral reproduction HTR2A;VDAC1;CREBBP GO:0019216| regulation of lipid metabolic process CREBBP;CYP1A1;PPARG;CNR1;HMGCR GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;CREBBP;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0034644| cellular response to UV PTGS2;CREBBP GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;CREBBP;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;CREBBP;PPARG GO:0006355| regulation of transcription, DNA-dependent CREBBP;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CREBBP GO:0006367| transcription initiation from RNA polymerase II promoter CREBBP;PPARG GO:0048511| rhythmic process AANAT;CREBBP;PPARG GO:0001666| response to hypoxia CHRNA7;CAT;CREBBP;CYP1A1 17482:[DB14011 DB02360] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways GO:0006955| immune response CTSG;OPRD1;CNR2 GO:0050778| positive regulation of immune response CTSG;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;CTSG GO:0019731| antibacterial humoral response CTSG;PLA2G1B GO:0032496| response to lipopolysaccharide CTSG;CNR2;PTGS2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1 GO:0043312| neutrophil degranulation CAT;CTSG;ALOX5 17483:[DB14011 DB01866] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01866|RU79256 SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;SRC;CAT GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0043066| negative regulation of apoptotic process GPX1;SRC;CAT;PTGS2;HMGCR;SOD1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;SRC GO:0009615| response to virus CYP1A1;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response PPARG;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process IDO1;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;SRC;SOD1 GO:0043065| positive regulation of apoptotic process SRC;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0008283| cell proliferation HTR1A;GPX1;SRC;CYP1A1 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0045453| bone resorption GPR55;SRC GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0007165| signal transduction CHRNA7;SRC;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 17484:[DB14011 DB07053] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes PPARG common pathways GO:0002674| negative regulation of acute inflammatory response PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0031100| organ regeneration PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0030224| monocyte differentiation PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042594| response to starvation ACAT1;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0030308| negative regulation of cell growth PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;ACAT1;AANAT GO:0006919| activation of caspase activity PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:1905461| PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1 GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0048469| cell maturation PPARG 17485:[DB14011 DB07265] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07265|3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID WEE1 common genes common pathways 17486:[DB14011 DB07450] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07450|(R)-minalrestat AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;AKR1B1;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0022900| electron transport chain GSR;IDO1;AKR1B1;CYP1A2 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2;HMGCR;SOD1;GPX1;CAT 17487:[DB14011 DB04942] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways GO:0007565| female pregnancy RARA;IDO1 GO:0010629| negative regulation of gene expression RARA;OPRD1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;RARB;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0045471| response to ethanol CAT;RARA;SOD1;CNR1;OPRM1;HMGCR GO:0006351| transcription, DNA-dependent RARA;RARB;PPARG GO:0001889| liver development ACAT1;RARA;CYP1A1 GO:0043401| steroid hormone mediated signaling pathway RARB;PPARG;RARA GO:0008285| negative regulation of cell proliferation RARA;OPRM1;PTGS2;CYP1B1;RARB;PPARG GO:0007165| signal transduction CHRNA7;RARA;HTR1A;GPR55;HTR2A;GPR12;CNR1;CRABP1;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;RARB;PPARG;GPR18;SMPD1 GO:0022008| neurogenesis RARB;DAGLA GO:0006367| transcription initiation from RNA polymerase II promoter RARB;PPARG;RARA GO:0033189| response to vitamin A RARA;CAT;CYP1A1;PPARG GO:0006355| regulation of transcription, DNA-dependent RARA;RARB;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RARA GO:0034097| response to cytokine stimulus PTGS2;RARA;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARB;TRPV4;TRPV1;PPARG;RARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARB;PLA2G1B;PPARG;RARA GO:0008284| positive regulation of cell proliferation RARB;PTGS2;HMGCR;HTR1A;HTR2A;RARA;CHRNA7 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;RARA;GPX1;RARB GO:0071300| cellular response to retinoic acid RARA;PPARG GO:0032526| response to retinoic acid PPARG;RARA GO:0045892| negative regulation of transcription, DNA-dependent PPARG;RARA GO:0001657| ureteric bud development RARB;RARA;CAT GO:0007283| spermatogenesis RARA;CNR1;SOD1 GO:0043277| apoptotic cell clearance RARA;ALOX15 GO:0010628| positive regulation of gene expression RARA;TRPV4 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;RARA;GPR18 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;RARA 17488:[DB14011 DB06943] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06943|(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol ADAM17 common genes common pathways GO:0001934| positive regulation of protein phosphorylation ADAM17;CHRNA7 GO:0007155| cell adhesion ADAM17;CYP1B1 GO:0008284| positive regulation of cell proliferation ADAM17;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;ADAM17;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0050830| defense response to Gram-positive bacterium ADAM17;PLA2G1B GO:0042493| response to drug ABCG2;TRPA1;PPARG;ADAM17;CYP1A1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0002446| neutrophil mediated immunity PLA2G1B;ADAM17 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;ADAM17 17489:[DB14011 DB00735] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00735|Naftifine SQLE common genes common pathways GO:0006725| cellular aromatic compound metabolic process SQLE;CYP1A2;CYP1B1 GO:0016126| sterol biosynthetic process SQLE;HMGCR GO:0010033| response to organic substance SQLE;SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0045540| regulation of cholesterol biosynthetic process HMGCR;SQLE GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;SQLE;CAT GO:0008203| cholesterol metabolic process SQLE;CAT;HMGCR GO:0006695| cholesterol biosynthetic process SQLE;HMGCR 17490:[DB14011 DB02846] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02846|L-thioproline ANXA5 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;ANXA5;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0010033| response to organic substance ANXA5;SOD1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;ANXA5;GPX1;CAT GO:0002576| platelet degranulation ANXA5;SOD1 17491:[DB14011 DB03673] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03673|Beta(2-Thienyl)Alanine PAH common genes common pathways GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1;PAH GO:0042136| neurotransmitter biosynthetic process PAH;DAGLA GO:0008152| metabolic process ACAT1;PAH;SMPD1 17492:[DB14011 DB04867] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04867|Lintitript CCKAR common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CCKAR;OPRD1;OPRM1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG;CCKAR GO:0007584| response to nutrient CNR1;HMGCR;PPARG;CCKAR GO:0046883| regulation of hormone secretion HTR1A;HTR2A;CCKAR GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;CCKAR;GPR18;PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;CCKAR GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;CCKAR;HTR2A;OPRM1 17493:[DB14011 DB00770] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0055085| transmembrane transport TRPV2;ABCC4;CACNA1H;SLCO3A1;TRPV3;ABCG2;SLCO2B1;TRPM8;ABCC5;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;SLC22A6;CACNA1G;ABCC1;SLCO2A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1;PTGDR2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;CYP1A2;PTGS2;ABCC4 GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC5;ABCC1;TRPV2 GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;PTGER2;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;PTGER1;CNR2;GPR18;PPARG GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;ABCC4;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT;ABCC4 GO:0099133| ABCC1;ABCC5;ABCC4 GO:0010243| response to organic nitrogen TRPV1;PTGS2;ABCC4 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2;HMGCR GO:0032496| response to lipopolysaccharide PTGER2;CNR1;CYP1A2;OPRM1;CNR2;PTGS2;PTGER1;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGER2;PTGS1;PTGS2 GO:0007218| neuropeptide signaling pathway PTGDR2;OPRM1;OPRD1;GLRA3;GLRB;GLRA1 GO:0002576| platelet degranulation SOD1;ABCC4 GO:0006811| ion transport CACNA1H;TRPV3;SLCO3A1;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;SLCO2B1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;ABCC4;AANAT;ACAT1 GO:0098656| SLC22A6;VDAC1 GO:0071380| cellular response to prostaglandin E stimulus PTGER2;PPARG GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway PTGDR2;OPRM1;OPRD1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;PTGER1;OPRM1;OPRD1;CHRNA7;PTGDR2;PTGER2 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;PTGDR2;GLRA1;CACNA1G;GLRB;VDAC1 GO:0006955| immune response PTGDR2;OPRD1;CNR2 17494:[DB14011 DB05956] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0006810| transport TRPV2;GRIN2B;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0008203| cholesterol metabolic process RXRA;HMGCR;CAT GO:0007611| learning or memory CHRNA7;GRIN2B;CNR1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;TRPV1;OPRM1;GLRA3;GRIN2B;SLC29A1;CHRNA7 GO:0032526| response to retinoic acid PPARG;RXRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;RXRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;RXRA;PPARG;CYP1A1 GO:0007566| embryo implantation PTGS2;SOD1;RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0065009| regulation of molecular function TRPV1;GRIN2B GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;CACNA1H;TRPV3;GRIN2B;GLRA3;TRPV2;CHRNA7 GO:0001890| placenta development SOD1;RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0045471| response to ethanol OPRM1;HMGCR;GRIN2B;SOD1;CNR1;CAT GO:0006351| transcription, DNA-dependent RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA GO:0007507| heart development RXRA;PPARG GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;HTR2A;GLRA3;GRIN2B;OPRD1;OPRM1 GO:0051289| protein homotetramerization CAT;TRPM8;TRPV1;TRPA1;RXRA;CRYZ GO:0016032| viral reproduction VDAC1;RXRA;HTR2A 17495:[DB14011 DB09256] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes CYP1A2;CYP3A5 common pathways GO:0010193| response to ozone CYP2E1;CAT GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0071615| oxidative deethylation CYP1A2 GO:0002933| CYP2C8;CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4;CYP1A2;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP2A6;CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2C8;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0007568| aging CYP1A1;TYMS;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A GO:0010468| regulation of gene expression CYP1A2 GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6;CYP2A6 GO:0033189| response to vitamin A CAT;CYP1A1;TYMS;PPARG GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TYMS;TRPA1;CAT;CYP1A2;PTGS2;CYP2E1;SOD1;HTR2A GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;GSR;IDO1;CYP2C8;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2A6;SOD1;CYP3A4;CYP2E1;PTGS1;ALOX5;GPX1;CAT GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C8;CYP2C19;CYP1A2;CYP2A6;CYP2E1 GO:0032259| methylation CYP1A2;TYMS GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0034097| response to cytokine stimulus TYMS;AANAT;PTGS2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;IDO1 GO:0007623| circadian rhythm AANAT;TYMS GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1;TYMS GO:0009636| response to toxin CYP1B1;TYMS;CYP1A1;CAT;GPX1 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2C8;CYP2D6;CYP2C9 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0097267| CYP2C8;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C8;CYP2C19;CYP1A2;CYP2A6;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP1B1;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP1A1;CYP2D6;CYP2C19 GO:0045471| response to ethanol TYMS;CAT;HMGCR;OPRM1;SOD1;CNR1;CYP2E1 17496:[DB14011 DB07416] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07416|(2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE IGKC common genes common pathways GO:0002376| immune system process IDO1;IGKC GO:0045087| innate immune response IGKC;PPARG GO:0001895| retina homeostasis SOD1;IGKC GO:0006955| immune response OPRD1;CNR2;IGKC 17497:[DB14011 DB04967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide CYP1B1;APEX1 GO:0045454| cell redox homeostasis GSR;APEX1;GPX1 GO:1900087| APEX1;CYP1A1 GO:0071320| cellular response to cAMP AANAT;APEX1 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0016032| viral reproduction VDAC1;TOP1;HTR2A GO:0006351| transcription, DNA-dependent APEX1;PPARG GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;TOP2A;SMPD1;CNR1;SOD1;PTGS2 GO:0048511| rhythmic process TOP1;AANAT;TOP2A;PPARG GO:0007568| aging PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CAT;CYP1A1;APEX1 GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;APEX1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0006355| regulation of transcription, DNA-dependent APEX1;PPARG GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;APEX1;HTR2A;SOD1;TOP1;PTGS2;CYP1A2;CAT GO:0010243| response to organic nitrogen TRPV1;APEX1;PTGS2 GO:0007623| circadian rhythm TOP1;AANAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B 17498:[DB14011 DB07422] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation CYP1A1;AR;GPX1;HTR1A GO:0008285| negative regulation of cell proliferation AR;OPRM1;PTGS2;CYP1B1;PPARG GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;AR;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;AR GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;AR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport AR;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 17499:[DB14011 DB07205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07205|N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE YARS common genes common pathways GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;YARS GO:0006915| apoptotic process GPX1;VDAC1;YARS 17500:[DB14011 DB08788] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08788|3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0007165| signal transduction GPR18;PPARG;HSP90AA1;SMPD1;CACNA1I;PLA2G1B;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7 GO:0009409| response to cold TRPM8;HSP90AA1;PPARG;TRPA1 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AA1;TRPV1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 17501:[DB14011 DB06094] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06094|Apatorsen HSPB1 common genes common pathways GO:0043066| negative regulation of apoptotic process HSPB1;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0009615| response to virus CYP1A1;HSPB1 GO:1902176| GPX1;HSPB1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;HSPB1 GO:0035556| intracellular signal transduction PLA2G1B;HSPB1 GO:0001895| retina homeostasis SOD1;HSPB1 17502:[DB14011 DB05390] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05390|INS 316 P2RY2 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;P2RY2;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;P2RY2;PPARG;GPR18 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;P2RY2 17503:[DB14011 DB02366] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02366|CRA_10762 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 17504:[DB14011 DB08484] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08484|4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE FBP1 common genes common pathways GO:0008152| metabolic process FBP1;ACAT1;SMPD1 GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPV1;TRPM8;FBP1;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;PPARG;TRPV4;TRPV1 GO:0030308| negative regulation of cell growth PPARG;FBP1 17505:[DB14011 DB04974] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04974|AP1903 MTOR common genes common pathways GO:0008542| visual learning HMGCR;MTOR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;HTR2A GO:0043087| regulation of GTPase activity MTOR;SOD1 GO:0010942| positive regulation of cell death MTOR;PTGS2 GO:0010976| positive regulation of neuron projection development CNR1;MTOR GO:0001934| positive regulation of protein phosphorylation MTOR;CHRNA7 GO:0045859| regulation of protein kinase activity MTOR;SOD1 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;MTOR GO:0007420| brain development MTOR;ACAT1 GO:0007584| response to nutrient PPARG;MTOR;CNR1;HMGCR GO:0009791| post-embryonic development CYP1A2;MTOR GO:0032868| response to insulin stimulus AANAT;CAT;MTOR;TRPV4 GO:0071230| cellular response to amino acid stimulus GLRA1;MTOR GO:0030838| positive regulation of actin filament polymerization ALOX15;MTOR GO:0060135| maternal process involved in female pregnancy MTOR;CNR1 GO:0042060| wound healing OPRM1;ALOX15;MTOR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MTOR GO:0043278| response to morphine MTOR;CNR1;OPRM1 GO:0048661| positive regulation of smooth muscle cell proliferation MTOR;PTGS2;HMGCR GO:0007569| cell aging SOD1;MTOR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;MTOR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;MTOR GO:0048714| positive regulation of oligodendrocyte differentiation MTOR;PPARG GO:0010628| positive regulation of gene expression MTOR;TRPV4 GO:0042220| response to cocaine SMPD1;MTOR;OPRM1;CNR1 GO:0050769| positive regulation of neurogenesis OPRM1;MTOR GO:0043200| response to amino acid stimulus GLRA3;GLRB;MTOR 17506:[DB14011 DB02953] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02953|2-Thiomethyl-3-Phenylpropanoic Acid MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 17507:[DB14011 DB00417] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0006810| transport TRPV2;ABCC1;SLC15A1;CACNA1I;TRPV1;ABCG2 GO:0055085| transmembrane transport CACNA1G;ABCC1;SLC15A1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;SLC15A1;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I 17508:[DB14011 DB11691] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes OPRD1;OPRM1;CYP3A5;CYP3A4;CYP3A7 common pathways GO:0007600| sensory perception OPRK1;OPRM1;TRPV2 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0006955| immune response OPRK1;OPRD1;CNR2 GO:0008209| androgen metabolic process CYP3A4 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission OPRK1;VDAC1;GLRB;GLRA1;CACNA1G;HTR2A;GLRA3;OPRD1;OPRM1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0010629| negative regulation of gene expression OPRD1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0008152| metabolic process ACAT1;UGT1A3;SMPD1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2;CAT GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;TRPV1;OPRK1;TRPA1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0045471| response to ethanol SOD1;CNR1;OPRM1;HMGCR;CAT;OPRK1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0032868| response to insulin stimulus AANAT;CAT;OPRK1;TRPV4 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB5 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;OPRK1;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0007610| behavior HTR1A;HTR2A;OPRK1 GO:0070588| calcium ion transmembrane transport TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;CHRNA7;TRPV2;TRPV3;OPRM1;CACNA1H GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0044849| OPRK1;OPRM1 GO:0042908| xenobiotic transport ABCB5;ABCC1;ABCG2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;HTR2A GO:0071315| cellular response to morphine OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0043278| response to morphine OPRK1;OPRM1;CNR1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP3A43;PTGS1;ALOX5;GPX1;CAT GO:0032094| response to food CYP1A1;OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRD1;OPRM1;GLRA1;OPRK1;GLRB GO:0007626| locomotory behavior OPRM1;SOD1;OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;HTR2A GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CYP1A1;IDO1 GO:0042060| wound healing OPRM1;ALOX15 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR2;CNR1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0042220| response to cocaine SMPD1;OPRK1;CNR1;OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;ABCB5;TRPV3;CACNA1H GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;CHRNA7 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;UGT1A3;CYP1A2;CYP3A4 GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;CACNA1H;ABCB5 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRK1;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0071363| cellular response to growth factor stimulus TRPV1;OPRD1;CAT 17509:[DB14011 DB04471] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;ESR1;CAT GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007165| signal transduction CHRNA7;ESR1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR1 17510:[DB14011 DB08045] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08045|4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL HSP90AB1 common genes common pathways GO:0001890| placenta development HSP90AB1;PPARG;SOD1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;HSP90AB1;CYP2D6;CYP2C19;CYP3A5;CYP1B1 GO:0043524| negative regulation of neuron apoptosis SOD1;HSP90AB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HSP90AB1 GO:0042220| response to cocaine HSP90AB1;SMPD1;OPRM1;CNR1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1;HSP90AB1 GO:0043312| neutrophil degranulation HSP90AB1;CAT;ALOX5 GO:0043066| negative regulation of apoptotic process HSP90AB1;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0071407| cellular response to organic cyclic compound CYP1B1;HSP90AB1;CYP1A1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;HSP90AB1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 17511:[DB14011 DB06885] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0006810| transport TTR;TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0043312| neutrophil degranulation TTR;CAT;ALOX5 17512:[DB14011 DB02263] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;TRPM8;ABCG2;SLCO2A1;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H 17513:[DB14011 DB03072] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03072|2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone PARP1 common genes common pathways GO:0034599| cellular response to oxidative stress SOD1;PARP1;CAT;GPX1;GSR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0006915| apoptotic process PARP1;GPX1;VDAC1 GO:0071294| cellular response to zinc ion GLRA1;PARP1 GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PARP1 GO:0010332| response to gamma radiation GPX1;PARP1 17514:[DB14011 DB06311] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06311|Darapladib PLA2G4A common genes common pathways GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G4A GO:0036150| PLA2G4A;PLA2G1B GO:0009395| phospholipid catabolic process NAPEPLD;PLA2G4A GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PLA2G4A;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0036148| PLA2G1B;PLA2G4A GO:0008152| metabolic process SMPD1;PLA2G4A;ACAT1 GO:0036149| PLA2G4A;PLA2G1B GO:0036152| PLA2G4A;PLA2G1B GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G4A;PLA2G1B GO:0016042| lipid catabolic process NAPEPLD;PLA2G4A;DAGLA;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G4A GO:0036151| PLA2G4A;PLA2G1B GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLA2G4A GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;DAGLA;CYP2D6;ALOX15;PLA2G4A 17515:[DB14011 DB02696] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;B4GALT1 GO:0042127| regulation of cell proliferation B4GALT1;PTGS1;PTGS2 GO:0042060| wound healing ALOX15;B4GALT1;OPRM1 GO:0043312| neutrophil degranulation B4GALT1;CAT;ALOX5 GO:0007155| cell adhesion B4GALT1;CYP1B1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;B4GALT1;OPRM1;PTGS2 GO:0060055| angiogenesis involved in wound healing GPX1;B4GALT1 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;B4GALT1;SMPD1;IDO1;CYP1B1;TRPV1 17516:[DB14011 DB08121] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes PPARG common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0051974| negative regulation of telomerase activity PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:1904706| PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;PTGS2;CYP1A2 GO:0006919| activation of caspase activity PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0071300| cellular response to retinoic acid PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0031100| organ regeneration PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 17517:[DB14011 DB03192] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways GO:0006635| fatty acid beta-oxidation HSD17B4;ACAT1 GO:0006631| fatty acid metabolic process ALOX15;HSD17B4;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;HSD17B4;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1;ALOX5;GPX1;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0008210| estrogen metabolic process HSD17B4;CYP1B1 GO:0001649| osteoblast differentiation HSD17B4;CAT GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;HSD17B4;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1 GO:0008209| androgen metabolic process HSD17B4;CYP3A4 17518:[DB14011 DB14515] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14515|Magnesium lactate ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure PPARG;ATP1A1;SOD1;PTGS2;PTGS1 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;ATP1A1;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0086002| ATP1A1;CACNA1G GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;GLRA3;ATP1A1 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;ATP1A1;CAT 17519:[DB14011 DB06985] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways GO:0032526| response to retinoic acid PPARG;RBP4 GO:0030324| lung development RBP4;CYP1A2 GO:0042593| glucose homeostasis TRPV4;PPARG;RBP4;CNR1 GO:0042572| retinol metabolic process CYP1B1;RBP4 GO:0007507| heart development RBP4;PPARG GO:0045471| response to ethanol RBP4;CAT;SOD1;CNR1;HMGCR;OPRM1 GO:0007601| visual perception RBP4;CRYZ;GLRA1;CYP1B1;GLRB GO:0001523| retinoid metabolic process NAPEPLD;RBP4 GO:0050896| response to stimulus RBP4;TRPM8;TRPA1 17520:[DB14011 DB03405] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03405|N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide CTSK common genes common pathways GO:1903146| VDAC1;CTSK GO:0045453| bone resorption CTSK;GPR55 17521:[DB14011 DB07319] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07319|6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HSP90AA1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;HSP90AA1;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;HSP90AA1 GO:0009409| response to cold PPARG;HSP90AA1;TRPA1;TRPM8 17522:[DB14011 DB11157] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11157|Anthralin KRT2;MAPK8IP1;KRT12 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;MAPK8IP1 GO:0006355| regulation of transcription, DNA-dependent PPARG;MAPK8IP1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;MAPK8IP1 GO:0007601| visual perception GLRA1;CRYZ;KRT12;GLRB;CYP1B1 17523:[DB14011 DB08550] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08550|7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline PNMT common genes common pathways GO:0032259| methylation CYP1A2;PNMT 17524:[DB14011 DB03267] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0071356| cellular response to tumor necrosis factor PCK1;TRPV1 GO:0071456| cellular response to hypoxia PCK1;SLC29A1;PTGS2;OPRD1 GO:0007568| aging CYP1A1;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;PCK1;CAT GO:0042593| glucose homeostasis PCK1;CNR1;TRPV4;PPARG GO:0033993| response to lipid PCK1;PPARG GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PCK1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0071300| cellular response to retinoic acid PCK1;PPARG GO:0032868| response to insulin stimulus PCK1;AANAT;CAT;TRPV4 GO:0014823| response to activity CAT;PCK1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PCK1 GO:0071320| cellular response to cAMP AANAT;PCK1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;PCK1;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA 17525:[DB14011 DB00536] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00536|Guanidine argG;GAMT;RNASE1;DLG4;ALDH2;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A8;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;DLG4;HTR2A;TRPV4;TRPV1 GO:0040014| regulation of multicellular organism growth GAMT;SOD1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;HTR1A;DLG4;GPR55;GPR12;CNR1;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0006641| triglyceride metabolic process SLC22A4;CAT;GPX1 GO:0006855| drug transmembrane transport ABCC1;SLC22A1;SLC22A2;ABCG2;SLC22A3;SLC22A5;SLC47A1;SLC47A2 GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;SLC22A2;TRPM8;SLC22A1;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;SLC22A4;TRPV3;SLC22A3;CACNA1H;SLC22A5;GLRA3;SLC22A8 GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0006812| cation transport SLC22A2;TRPM8;SLC22A1 GO:0098656| SLC22A8;VDAC1 GO:0007399| nervous system development SMPD1;GLRB;DLG4 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;DLG4 GO:0008152| metabolic process SMPD1;ACAT1;ALDH2 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;DLG4;HTR2A;GLRA3;OPRM1;OPRD1 GO:0051260| protein homooligomerization GLRA1;SLC22A1;GLRA3;ACAT1 GO:0006936| muscle contraction GLRA1;CACNA1H;GAMT GO:0055085| transmembrane transport SLC22A3;CACNA1H;TRPV3;SLC22A4;DLG4;SLC22A5;SLC22A8;TRPV2;SLC47A1;SLC47A2;CACNA1G;SLC22A1;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;SLC22A2 GO:0034220| ion transmembrane transport SLC22A4;GLRA3;CHRNA7;GLRA1;TRPA1;TRPV1;GLRB GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;DLG4 GO:0007283| spermatogenesis CNR1;SOD1;GAMT GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0007612| learning PTGS2;DLG4;VDAC1 GO:0032259| methylation CYP1A2;GAMT GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;ALDH2;CYP3A7;CYP1A2;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0022900| electron transport chain CYP1A2;ALDH2;GSR;IDO1 17526:[DB14011 DB00738] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes CYP2C19;CYP1A1;CYP2D6;CYP3A5 common pathways GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0032259| methylation TRDMT1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP1B1;CYP2C9;CYP1A1;CYP4A11;CYP1A2 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0009615| response to virus CYP1A1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C8;PTGS2;CYP3A7;CYP1A2;CYP4A11;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0006631| fatty acid metabolic process ALOX15;CYP4A11;PTGS2;PTGS1 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 GO:0006691| leukotriene metabolic process CYP4A11;ALOX5;ABCC1;ALOX15 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0009308| amine metabolic process CYP1A1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;CYP4A11;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CYP1A1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0009611| response to wounding CYP1A1;GPX1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C8;CYP2C19 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0010041| response to iron(III) ion CYP1A1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0002933| CYP2C8;CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0051100| negative regulation of binding CYP2D6 GO:0070988| demethylation CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0009692| ethylene metabolic process CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C19;CYP2C9 GO:0048565| digestive tract development CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0032502| developmental process CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0019216| regulation of lipid metabolic process CNR1;CYP4A11;HMGCR;CYP1A1;PPARG GO:0001975| response to amphetamine TRDMT1;SOD1;CNR2 GO:1900087| CYP1A1 GO:0097267| CYP1A2;CYP4A11;CYP1B1;CYP2C8;CYP2C19;CYP1A1;CYP2C9 GO:0043010| camera-type eye development CYP1A1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C8;CYP3A5 GO:0009624| response to nematode CYP1A1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0009636| response to toxin GPX1;CAT;CYP1B1;CYP1A1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 17527:[DB14011 DB12569] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12569|Tonapofylline ADORA1 common genes common pathways GO:0016042| lipid catabolic process NAPEPLD;ADORA1;DAGLA;PLA2G1B GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0001666| response to hypoxia CAT;CHRNA7;ADORA1;CYP1A1 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;ADORA1;PPARG;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0097756| ADORA1;PTGS2;HMGCR GO:0060087| relaxation of vascular smooth muscle ADORA1;SOD1 GO:0050728| negative regulation of inflammatory response CNR2;ADORA1 GO:0051967| negative regulation of synaptic transmission, glutamatergic ADORA1;HTR2A GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;ADORA1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0043066| negative regulation of apoptotic process ADORA1;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0035307| positive regulation of protein dephosphorylation SMPD1;ADORA1 GO:0032229| negative regulation of synaptic transmission, GABAergic ADORA1;CNR2 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADORA1 GO:0045777| positive regulation of blood pressure CNR1;ADORA1 GO:0008285| negative regulation of cell proliferation CYP1B1;ADORA1;PPARG;PTGS2;OPRM1 GO:0050890| cognition ADORA1;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADORA1;OPRD1;OPRM1 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;ADORA1;PPARG;SMPD1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ADORA1;ALOX5;PTGS1;PTGS2;CNR2 GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1;ADORA1 GO:0045776| negative regulation of blood pressure CNR1;ADORA1 GO:0001659| temperature homeostasis HTR2A;GPX1;ADORA1;TRPV1 GO:0007399| nervous system development SMPD1;ADORA1;GLRB 17528:[DB14011 DB03008] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03008|5-fluoro-beta-L-gulosyl fluoride MAN2A1 common genes common pathways GO:0001889| liver development ACAT1;CYP1A1;MAN2A1 GO:0008152| metabolic process ACAT1;MAN2A1;SMPD1 GO:0050769| positive regulation of neurogenesis MAN2A1;OPRM1 17529:[DB14011 DB00882] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes CYP1A1;CYP1A2 common pathways GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV1;ABCB1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0042359| vitamin D metabolic process CYP11A1;CYP3A4;CYP1A1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0010193| response to ozone CAT;CYP2E1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;CYP1A2;PTGS2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP11A1;CYP2E1;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0009611| response to wounding GPX1;CYP1A1 GO:0007568| aging CYP1A1;CAT;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2 GO:0006810| transport ABCC1;ABCG2;TRPV1;ABCB1;CACNA1I;TRPV2 GO:0010468| regulation of gene expression CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0010041| response to iron(III) ion CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032094| response to food OPRM1;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0022900| electron transport chain CYP19A1;GSR;IDO1;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0042493| response to drug ABCB1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;CYP2E1;SOD1;HTR2A GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0055114| oxidation-reduction process CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP19A1;CYP2C9;CYP1A1;CAT;ALOX5;GPX1;PTGS1;CYP11A1;SOD1;CYP3A4;CYP2E1;HMGCR;PTGS2;CYP3A7;CYP1A2 GO:0009308| amine metabolic process CYP1A1 GO:0006694| steroid biosynthetic process CYP11A1;HMGCR;CYP19A1;CYP17A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0010243| response to organic nitrogen TRPV1;PTGS2;CYP2E1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0008203| cholesterol metabolic process HMGCR;CYP11A1;CAT GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;CYP1A1;IDO1 GO:0030324| lung development CYP1A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0032259| methylation CYP1A2 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0009615| response to virus CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR1 GO:0009636| response to toxin CAT;GPX1;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0045333| cellular respiration CYP1A2 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0009624| response to nematode CYP1A1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0017143| insecticide metabolic process CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:1900087| CYP1A1 GO:0032502| developmental process CYP1A1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV4;TRPV1 GO:0043010| camera-type eye development CYP1A1 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;ESR1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0009635| response to herbicide CYP1A1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0009692| ethylene metabolic process CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0070988| demethylation CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0045471| response to ethanol OPRM1;HMGCR;CYP2E1;SOD1;CNR1;CAT GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;PTGS1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP19A1;CYP11A1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;CYP11A1;NAAA;GPX1;PTGS1;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0006706| steroid catabolic process CYP3A4;CYP1A2 17530:[DB14011 DB03841] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03841|Y-700 XDH common genes common pathways GO:0006919| activation of caspase activity XDH;PPARG GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0010629| negative regulation of gene expression OPRD1;XDH GO:0007595| lactation SLC29A1;XDH GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;XDH GO:0022900| electron transport chain GSR;IDO1;CYP1A2;XDH 17531:[DB14011 DB03882] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03882|5-Alpha-Androstane-3-Beta,17beta-Diol ESR2;SHBG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;ESR2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;ESR2;PPARG GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR2 GO:0006351| transcription, DNA-dependent PPARG;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG GO:0007165| signal transduction GPR18;PPARG;SMPD1;ESR2;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 17532:[DB14011 DB07234] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;MAPKAPK2;TRPV1;IDO1;ALOX15 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;MAPKAPK2 GO:0034097| response to cytokine stimulus AANAT;PTGS2;MAPKAPK2 GO:0032496| response to lipopolysaccharide IDO1;MAPKAPK2;CYP1A1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0006691| leukotriene metabolic process ABCC1;MAPKAPK2;ALOX15;ALOX5 17533:[DB14011 DB05284] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05284|CA4P TUBB common genes common pathways GO:0043312| neutrophil degranulation TUBB;ALOX5;CAT 17534:[DB14011 DB08498] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0043200| response to amino acid stimulus CASP3;GLRA3;GLRB GO:0006915| apoptotic process CASP3;GPX1;VDAC1 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;CASP3 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CASP3;SOD1;CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CASP3;CAT;PTGS2;CYP1A2 GO:0009611| response to wounding GPX1;CASP3;CYP1A1 GO:0007605| sensory perception of sound SOD1;CASP3;GPX1 GO:0071407| cellular response to organic cyclic compound CASP3;CYP1B1;CYP1A1 GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CASP3;CAT GO:0035094| response to nicotine CASP3;CHRNA7;CNR1 GO:0007611| learning or memory CASP3;CHRNA7;CNR1 GO:0042060| wound healing OPRM1;CASP3;ALOX15 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1;CASP3 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;CASP3;SOD1;PTGS2;HMGCR GO:0046677| response to antibiotic SOD1;CASP3;CYP1A1 GO:0006919| activation of caspase activity PPARG;CASP3 GO:0009411| response to UV CASP3;CAT GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT;CASP3 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CASP3;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0042542| response to hydrogen peroxide SOD1;GPX1;CASP3;CAT;TRPA1 GO:0007507| heart development CASP3;PPARG GO:0045165| cell fate commitment CASP3;PPARG 17535:[DB14011 DB01969] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 17536:[DB14011 DB00172] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;PPIF GO:0070301| cellular response to hydrogen peroxide PPIF;CYP1B1 GO:0008285| negative regulation of cell proliferation P3H3;OPRM1;P3H2;PTGS2;PPARG;CYP1B1;P3H1 GO:0051881| regulation of mitochondrial membrane potential SOD1;PYCR1;OPRD1 GO:0009636| response to toxin CYP1A1;CYP1B1;CAT;GPX1;SLC6A14 GO:0008152| metabolic process ACAT1;EPRS;SMPD1 GO:0071277| cellular response to calcium ion PPIF;ALOX15 GO:0010942| positive regulation of cell death PRODH;PTGS2 GO:0016032| viral reproduction HTR2A;PPIA;VDAC1 GO:0008631| induction of apoptosis by oxidative stress PRODH;CYP1B1;GPX1 GO:0006979| response to oxidative stress SOD1;PTGS2;PPIF;CAT;PTGS1;GPX1 GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;SLC6A7;TRPV2;SLC6A14 GO:0055085| transmembrane transport VDAC1;CACNA1I;TRPV4;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;SLC6A14;TRPV2;SLC16A10;TRPV3;CACNA1H GO:0050714| positive regulation of protein secretion PPIA;PLA2G1B GO:0006915| apoptotic process GPX1;PPIF;VDAC1 GO:0043312| neutrophil degranulation ALOX5;CAT;PPIA GO:0035722| interleukin-12-mediated signaling pathway PPIA;SOD1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;PPIF GO:0030199| collagen fibril organization P4HA1;CYP1B1 GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;PYCR1;PYCR2;GSR GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;PRODH;P3H1;P4HA1;CYP1B1;CYP3A4;P3H3;SOD1;PYCR2;PTGS2;CYP3A7;P4HA2;P3H2;CYP1A2;PYCR1;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0022900| electron transport chain CYP1A2;P4HA2;GSR;IDO1 17537:[DB14011 DB01989] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways 17538:[DB14011 DB00269] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0008209| androgen metabolic process CYP19A1;CYP3A4;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP19A1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV4;TRPV1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;ESR1;HTR1A;GPR55 GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9;CYP19A1;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0022900| electron transport chain CYP1A2;CYP19A1;IDO1;GSR GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0006694| steroid biosynthetic process CYP17A1;CYP19A1;HMGCR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV4;TRPV1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;ESR1 17539:[DB14011 DB07906] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07906|[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 17540:[DB14011 DB02419] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways GO:0016032| viral reproduction HTR2A;VDAC1;PPIA GO:0035722| interleukin-12-mediated signaling pathway SOD1;PPIA GO:0043312| neutrophil degranulation PPIA;CAT;ALOX5 GO:0050714| positive regulation of protein secretion PPIA;PLA2G1B 17541:[DB14011 DB12128] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12128|Ulimorelin GHSR common genes common pathways GO:0007283| spermatogenesis GHSR;SOD1;CNR1 GO:0046697| decidualization GHSR;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18;GHSR GO:0032355| response to estradiol stimulus GHSR;CAT;CYP1A2;PTGS2 GO:0032094| response to food OPRM1;GHSR;CYP1A1 GO:0032100| positive regulation of appetite OPRM1;GHSR GO:0050728| negative regulation of inflammatory response CNR2;GHSR GO:0007611| learning or memory GHSR;CHRNA7;CNR1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;GHSR GO:0009725| response to hormone stimulus GHSR;ACAT1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;GHSR GO:0007565| female pregnancy IDO1;GHSR GO:0060259| regulation of feeding behavior CNR1;GHSR 17542:[DB14011 DB07405] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways GO:0001666| response to hypoxia CYP1A1;NOS2;CAT;CHRNA7 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;NOS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NOS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;NOS2;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0050796| regulation of insulin secretion NOS2;CNR1 GO:0045454| cell redox homeostasis GSR;NOS2;GPX1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045776| negative regulation of blood pressure NOS2;CNR1 17543:[DB14011 DB08746] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08746|1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 17544:[DB14011 DB00711] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes PTGS1;ALOX5 common pathways GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;BCHE GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0043312| neutrophil degranulation ALOX5;CAT GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0042493| response to drug SMPD1;ABCC1;BCHE;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR GO:2001300| ALOX5 17545:[DB14011 DB01326] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01326|Cefamandole SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0055085| transmembrane transport SLC22A8;TRPV3;CACNA1H;SLC22A11;SLC22A7;TRPV2;TRPA1;ABCC1;CACNA1G;SLC22A6;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0006811| ion transport SLC22A7;SLC22A11;CHRNA7;TRPV2;SLC22A8;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPA1;GLRA1;CACNA1G GO:0098656| SLC22A8;SLC22A7;SLC22A6;VDAC1 GO:0046415| urate metabolic process SLC22A11;ABCG2 17546:[DB14011 DB07627] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07627|(2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CAPN1;CHRNA7 GO:0043312| neutrophil degranulation CAPN1;ALOX5;CAT 17547:[DB14011 DB05420] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0015949| nucleobase-containing small molecule interconversion RRM1;GSR GO:0008152| metabolic process ACAT1;SMPD1;RRM1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;RRM1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT 17548:[DB14011 DB03187] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways GO:0032259| methylation GCSH;CYP1A2 17549:[DB14011 DB07329] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07329|1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID IGHG2 common genes common pathways GO:0045087| innate immune response IGHG2;PPARG GO:0002376| immune system process IDO1;IGHG2 17550:[DB14011 DB05798] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways GO:0035556| intracellular signal transduction PRKAR2A;PRKAR1A;PLA2G1B GO:0007507| heart development PRKAR1A;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PRKAR1A;PPARG GO:0045859| regulation of protein kinase activity PRKAR1A;SOD1 17551:[DB14011 DB05533] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05533|QR-333 AKR1B1 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;AKR1B1;PPARG;CYP1A1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;AKR1B1 GO:0055114| oxidation-reduction process CRYZ;AKR1B1;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0022900| electron transport chain IDO1;GSR;AKR1B1;CYP1A2 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2;HMGCR 17552:[DB14011 DB08194] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08194|4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine HSP90AA1 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0046677| response to antibiotic SOD1;CYP1A1;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HSP90AA1 GO:0009409| response to cold TRPM8;PPARG;HSP90AA1;TRPA1 GO:0009408| response to heat TRPV2;SOD1;TRPV3;TRPV1;HSP90AA1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;HSP90AA1;PPARG;GPR18;PLA2G1B;CACNA1I 17553:[DB14011 DB07733] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0050727| regulation of inflammatory response PTGS2;CASP1 GO:0007165| signal transduction SMPD1;PPARG;CASP1;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7 GO:0006919| activation of caspase activity PPARG;CASP1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CASP1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0006915| apoptotic process GPX1;CASP1;VDAC1 GO:0001666| response to hypoxia CHRNA7;CAT;CASP1;CYP1A1 17554:[DB14011 DB06961] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06961|5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide HSP90AA1 common genes common pathways GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;HSP90AA1 GO:0009409| response to cold PPARG;HSP90AA1;TRPA1;TRPM8 GO:0007165| signal transduction SMPD1;HSP90AA1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HSP90AA1;PTGS2;OPRM1 17555:[DB14011 DB14012] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14012|Burosumab FGF23 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;FGF23;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0042359| vitamin D metabolic process CYP3A4;FGF23;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent FGF23;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGF23 17556:[DB14011 DB07978] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy IDO1;DHODH GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1;DHODH GO:0014070| response to organic cyclic compound ACAT1;AANAT;DHODH;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;DHODH;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT;DHODH GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0031000| response to caffeine DHODH;PPARG 17557:[DB14011 DB08735] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08735|R,S-Warfarin alcohol ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0098869| ALB;GSR;PTGS2;CAT;GPX1;PTGS1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ALB GO:0002576| platelet degranulation ALB;SOD1 17558:[DB14011 DB11300] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11300|Thrombin F2R;F2RL3;F11;F13A1;F13B;FGA;FGB;FGG;F5;F8 common genes common pathways GO:0009611| response to wounding F2R;GPX1;F2RL3;CYP1A1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;F2R;TRPV1;TRPA1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;F2R;GPR55;GPR18;F2RL3;PPARG GO:0035025| positive regulation of Rho protein signal transduction GPR18;F2RL3;GPR55;F2R GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2R;CAT GO:0002376| immune system process FGA;IDO1;FGB GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;FGB;GPR55;F2R;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;FGA;FGG GO:0050714| positive regulation of protein secretion FGB;FGG;PLA2G1B;FGA GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger F2RL3;GPR18;F2R;GPR55 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;F2R;CNR2;PTGS2;OPRM1;CYP1A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;F2R;HTR2A;F2RL3 GO:0002576| platelet degranulation SOD1;FGB;FGG;F8;F5;FGA;F13A1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;F2R;HTR1A;HMGCR;PTGS2 GO:0045087| innate immune response FGA;PPARG;FGB GO:0045893| positive regulation of transcription, DNA-dependent PPARG;F2R GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;F8;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;F2R;HTR2A GO:0099553| CNR1;F2R GO:0045907| positive regulation of vasoconstriction FGA;FGG;FGB;PTGS2;HTR2A;F2R GO:0034116| positive regulation of heterotypic cell-cell adhesion FGG;ALOX15;FGA;FGB GO:0007165| signal transduction FGB;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;F2R;GPR55;HTR2A;GPR12;CNR1;CACNA1I;PLA2G1B;FGA;FGG;SMPD1;F2RL3;PPARG;GPR18 GO:0051930| regulation of sensory perception of pain F2R;OPRD1;OPRM1 GO:0006919| activation of caspase activity PPARG;F2R GO:0045987| positive regulation of smooth muscle contraction F2R;PTGS2 GO:1902042| FGB;GPX1;FGA;FGG GO:0008285| negative regulation of cell proliferation F2R;PTGS2;OPRM1;CYP1B1;PPARG GO:0051592| response to calcium ion AANAT;FGB;FGG;FGA GO:0043524| negative regulation of neuron apoptosis SOD1;F2R GO:0006954| inflammatory response ALOX5;PTGS1;F2R;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:2000778| positive regulation of interleukin-6 secretion F2R;TRPV4 17559:[DB14011 DB05025] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05025|Arimoclomol SOD1 common genes SOD1 common pathways GO:0046620| regulation of organ growth SOD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0001895| retina homeostasis SOD1 GO:0006749| glutathione metabolic process SOD1;GPX1;GSR GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0001890| placenta development PPARG;SOD1 GO:0032930| positive regulation of superoxide anion generation SOD1 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0072593| reactive oxygen species metabolic process SOD1 GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0040014| regulation of multicellular organism growth SOD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0002262| myeloid cell homeostasis SOD1 GO:0060047| heart contraction SOD1;GPX1 GO:0001819| positive regulation of cytokine production SOD1 GO:0043524| negative regulation of neuron apoptosis SOD1 GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels SOD1 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0009408| response to heat TRPV1;TRPV3;SOD1;TRPV2 GO:0043087| regulation of GTPase activity SOD1 GO:0019226| transmission of nerve impulse SOD1 GO:0019430| removal of superoxide radicals SOD1 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 GO:0000303| response to superoxide SOD1 GO:0008090| retrograde axon cargo transport SOD1 GO:0045471| response to ethanol CAT;SOD1;CNR1;OPRM1;HMGCR GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;TRPA1 GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0001541| ovarian follicle development SOD1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B GO:0007283| spermatogenesis CNR1;SOD1 GO:0046688| response to copper ion SOD1;AANAT GO:0046716| muscle cell homeostasis SOD1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0042554| superoxide anion generation SOD1 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT;CYP1A1 GO:0048538| thymus development SOD1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0043085| positive regulation of catalytic activity SOD1 GO:0007605| sensory perception of sound GPX1;SOD1 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0007569| cell aging SOD1 GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0034465| response to carbon monoxide SOD1 GO:0006801| superoxide metabolic process SOD1 GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0034599| cellular response to oxidative stress GSR;CAT;GPX1;SOD1 GO:0097332| SOD1 GO:0007626| locomotory behavior OPRM1;SOD1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0002576| platelet degranulation SOD1 GO:0035722| interleukin-12-mediated signaling pathway SOD1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2 GO:1902177| SOD1 17560:[DB14011 DB06824] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06824|Triethylenetetramine GPC1 common genes common pathways GO:0001523| retinoid metabolic process GPC1;NAPEPLD 17561:[DB14011 DB07174] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07174|6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-4-(3-METHOXYPROPYL)-2,2-DIMETHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE REN common genes common pathways GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;REN GO:0048469| cell maturation PPARG;REN GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1;REN GO:0051591| response to cAMP AANAT;REN GO:0001822| kidney development CAT;REN GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;REN GO:0032496| response to lipopolysaccharide CYP1A1;REN;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;REN;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT 17562:[DB14011 DB06245] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways GO:0016032| viral reproduction VDAC1;KRT8;HTR2A GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ANXA2;PLAUR GO:0043524| negative regulation of neuron apoptosis SOD1;LRP1 GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1;LRP1;PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15 GO:0042953| lipoprotein transport LRP1;PPARG GO:0001503| ossification ALOX15;CLEC3B GO:0051592| response to calcium ion AANAT;FGA GO:0045773| positive regulation of axon extension TRPV2;FN1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;LAMA1;TRPA1 GO:0001525| angiogenesis PTGS2;ANXA2;FN1;CYP1B1;LAMA5 GO:1902042| FGA;GPX1 GO:0001523| retinoid metabolic process LRP1;NAPEPLD GO:0045740| positive regulation of DNA replication PLA2G1B;CALR GO:0048146| positive regulation of fibroblast proliferation ANXA2;PLA2G1B;FN1 GO:0008283| cell proliferation LRP1;CYP1A1;LAMA5;HTR1A;GPX1 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;PLA2G1B;CACNA1I;PLAUR;FGA;SMPD1;PPARG;GPR18 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;FGA GO:0045907| positive regulation of vasoconstriction FGA;HTR2A;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0051702| interaction with symbiont GPX1;FN1 GO:0007517| muscle organ development LAMA5;CACNA1H GO:0042493| response to drug ABCC1;SMPD1;CALR;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0043312| neutrophil degranulation PLAUR;ALOX5;ANXA2;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;PPARG;TRPV4;TRPV1 GO:0007155| cell adhesion CYP1B1;LAMA5;LAMB1;LAMA1;FN1;LAMA3;LAMC1 GO:0045087| innate immune response PPARG;FGA GO:0043066| negative regulation of apoptotic process PLAUR;SERPINB2;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;ANXA2;SERPINB2;CANX GO:0002576| platelet degranulation SOD1;FGA;CLEC3B;FN1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;FN1;CALR GO:0030199| collagen fibril organization CYP1B1;ANXA2 GO:0030324| lung development CYP1A2;LAMA5 GO:0042127| regulation of cell proliferation LAMA5;PTGS2;PTGS1 GO:0042060| wound healing OPRM1;ALOX15;SERPINB2;FN1 GO:0010033| response to organic substance TRPA1;CALR;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CALR GO:0010977| negative regulation of neuron projection development LRP1;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;FN1;CALR GO:0007283| spermatogenesis CALR;SOD1;CNR1 GO:0043277| apoptotic cell clearance LRP1;ALOX15 GO:0050714| positive regulation of protein secretion FGA;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;FGA;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPV4;TRPM8;CALR GO:0043388| positive regulation of DNA binding PLAUR;PPARG GO:0002376| immune system process IDO1;FGA GO:0007568| aging CANX;CYP1A1;LRP1;CAT;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR GO:0030282| bone mineralization PTGS2;CLEC3B;ALOX15 GO:0032355| response to estradiol stimulus CALR;CYP1A2;PTGS2;CAT GO:0009611| response to wounding GPX1;CYP1A1;FN1 17563:[DB14011 DB08010] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08010|(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways GO:0048511| rhythmic process AANAT;MAPK10;PPARG GO:0009416| response to light stimulus MAPK10;AANAT GO:0000187| activation of MAPK activity PLA2G1B;MAPK10;CHRNA7;SOD1 GO:0010468| regulation of gene expression MAPK10;CYP1A2 GO:0042752| regulation of circadian rhythm MAPK10;PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;MAPK10;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 17564:[DB14011 DB02510] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02510|'5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine EPRS common genes common pathways GO:0008152| metabolic process EPRS;SMPD1;ACAT1 17565:[DB14011 DB05424] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05424|Canertinib EGFR common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPV1;EGFR;TRPA1 GO:0051592| response to calcium ion EGFR;AANAT GO:0001889| liver development EGFR;CYP1A1;ACAT1 GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;PPARG GO:0006970| response to osmotic stress TRPV4;EGFR GO:0001503| ossification EGFR;ALOX15 GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;EGFR GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0007165| signal transduction EGFR;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2;OPRD1 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2;HTR2A GO:0008283| cell proliferation GPX1;HTR1A;EGFR;CYP1A1 GO:0014070| response to organic cyclic compound EGFR;CYP1A1;PPARG;TRPA1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0071276| cellular response to cadmium ion EGFR;CYP1A2;SOD1 GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0030324| lung development EGFR;CYP1A2 GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0007623| circadian rhythm EGFR;AANAT GO:0042127| regulation of cell proliferation EGFR;PTGS2;PTGS1 GO:0042060| wound healing ALOX15;EGFR;OPRM1 GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0008284| positive regulation of cell proliferation EGFR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;EGFR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;EGFR GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;EGFR GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;EGFR;TRPV1 GO:0006979| response to oxidative stress EGFR;CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;EGFR;TRPV1 GO:0033993| response to lipid EGFR;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;EGFR;TRPV4 GO:0043406| positive regulation of MAP kinase activity HTR2A;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EGFR 17566:[DB14011 DB05219] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes CYP2C9 common pathways GO:0002933| CYP3A4;CYP3A7;CYP2C8;CYP3A5;CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP2B6 GO:0007568| aging SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PDE4D;PTGS2;CAT;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;PDE4A;PDE4D;OPRM1;CNR2;GPR18;PPARG;PDE4B;PDE4C GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP2B6;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP17A1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP2B6;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2C8;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0030593| neutrophil chemotaxis PDE4D;PDE4B;PLA2G1B GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2B6;CYP2C9;CYP1A1;CYP2C19;CYP2C8;CYP1B1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0019627| urea metabolic process CYP2C9 GO:0007165| signal transduction PDE4D;PDE4A;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;PDE4B;PDE4C GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C8;CYP2C19;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2C8;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0006939| smooth muscle contraction HTR2A;PDE4D GO:0043603| cellular amide metabolic process CYP2C9 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2B6;CYP2C19;CYP2C8 GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP2B6;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 17567:[DB14011 DB00890] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00890|Dienestrol ESR1;SHBG common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;ESR1;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;ESR1;OPRM1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TRPV1 GO:0032355| response to estradiol stimulus CAT;ESR1;CYP1A2;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG 17568:[DB14011 DB05469] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ADRA1A;TRPV4;TRPV1;ADRA1D;ADRA1B;HTR2A;OPRM1 GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0045907| positive regulation of vasoconstriction ADRA1B;HTR2A;PTGS2;ADRA1A;ADRA1D GO:0007165| signal transduction GPR18;PPARG;SMPD1;ADRA1D;PLA2G1B;CACNA1I;ADRA1A;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;ADRA1B GO:0009725| response to hormone stimulus ADRA1A;ACAT1 GO:0008283| cell proliferation CYP1A1;ADRA1D;HTR1A;ADRA1B;GPX1 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D GO:0008285| negative regulation of cell proliferation ADRA1A;CYP1B1;PPARG;PTGS2;OPRM1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRA1B;CNR1;ADRA1D GO:0035556| intracellular signal transduction ADRA1A;PLA2G1B;ADRA1B GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;ADRA1A;GPR18;PPARG;ADRA1D GO:0007568| aging NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CAT;CYP1A1;ADRA1A GO:0042593| glucose homeostasis CNR1;ADRA1B;PPARG;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;ALOX15;ADRA1A;TRPV4 GO:0006915| apoptotic process VDAC1;ADRA1A;GPX1 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;ADRA1A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1D;ADRA1A;OPRD1;OPRM1;HTR2A;ADRA1B GO:0008284| positive regulation of cell proliferation ADRA1D;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ADRA1A;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT 17569:[DB14011 DB00991] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00991|Oxaprozin PTGS1;PTGS2 common genes PTGS1;PTGS2 common pathways GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CYP1A1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning PTGS2;VDAC1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP2C9;CYP1A1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0010042| response to manganese ion PTGS2 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;TRPV1;TRPA1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0010942| positive regulation of cell death PTGS2 17570:[DB14011 DB03003] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03003|Glutathione Sulfonic Acid gstA;GSTM4;GSTA1;GSTP1 common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B GO:0009636| response to toxin GPX1;CAT;CYP1B1;GSTP1;CYP1A1 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0006749| glutathione metabolic process SOD1;GPX1;GSTM4;GSTA1;GSTP1;GSR GO:0042178| xenobiotic catabolic process GSTM4;CRYZ GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CAT;GSTP1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;GSTP1;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0008152| metabolic process GSTP1;GSTA1;SMPD1;GSTM4;ACAT1 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:1904706| GSTP1;PPARG GO:0032355| response to estradiol stimulus GSTP1;PTGS2;CYP1A2;CAT GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production GSTP1;GPR18;CHRNA7 GO:0098869| GSR;GSTA1;GSTP1;CAT;PTGS1;GPX1;PTGS2 GO:0043200| response to amino acid stimulus GLRA3;GLRB;GSTP1 GO:0030855| epithelial cell differentiation PPARG;GSTA1;VDAC1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0000302| response to reactive oxygen species SOD1;CAT;GPX1;GSTP1 GO:0034599| cellular response to oxidative stress GSTP1;GSR;SOD1;GPX1;CAT GO:0043066| negative regulation of apoptotic process GSTP1;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0043312| neutrophil degranulation GSTP1;ALOX5;CAT 17571:[DB14011 DB02750] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways GO:0009636| response to toxin CYP1A1;CYP1B1;SLC7A8;GPX1;CAT GO:0007399| nervous system development GLRB;SLC7A5;SMPD1 GO:0006810| transport TRPV2;SLC7A8;SLC7A5;ABCG2;TRPV1;CACNA1I;ABCC1 17572:[DB14011 DB11638] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes CYP2C19;CYP2D6 common pathways GO:0042493| response to drug ABCG2;ABCC1;SMPD1;LDHA;TRPA1;PPARG;CYP1A1;HNRNPD;LGALS1;CAT;PTGS2;CYP1A2;SOD1;HTR2A;SRP14 GO:0006355| regulation of transcription, DNA-dependent KHSRP;HNRNPD;HP1BP3;SFPQ;SF1;ENO1;HNRNPK;EEF1A1;DDX5;PPARG;HSPA8 GO:0032094| response to food OPRM1;G6PD;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;LGALS1 GO:0045893| positive regulation of transcription, DNA-dependent NPM1;PPARG;HNRNPD GO:1902176| HSPB1;GPX1 GO:0030224| monocyte differentiation PPARG;MYH9 GO:0035900| response to isolation stress LGALS1;NAPEPLD GO:0007569| cell aging SOD1;NPM1 GO:0055114| oxidation-reduction process LDHA;FTO;CYP2C9;CYP1A1;GAPDHS;CRYZ;CYP1B1;PRDX1;LDHB;G6PD;CYP17A1;CYP3A5;ALOX15;ALDH7A1;CYP2D6;CYP2C19;IDO1;GSR;CYP3A7;PTGS2;CYP1A2;P4HB;MDH1;HMGCR;CYP3A4;GAPDH;SOD1;CYCS;ALOX5;PTGS1;GPX1;CAT GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process CYP1B1;CYP2D6;DAGLA;ALOX15;FAAH GO:0043278| response to morphine GPI;CNR1;OPRM1 GO:0016525| negative regulation of angiogenesis PGK1;PPARG GO:0007015| actin filament organization ALDOA;PLA2G1B;TRPV4;TPM1;CFL1 GO:0042127| regulation of cell proliferation PTGS1;HP1BP3;PTGS2 GO:0042060| wound healing TPM1;OPRM1;ALOX15;DSP GO:0000302| response to reactive oxygen species SOD1;GPX1;CAT;PRDX1 GO:0043523| regulation of neuron apoptosis G6PD;GPX1 GO:0030838| positive regulation of actin filament polymerization ALOX15;PFN1 GO:0030308| negative regulation of cell growth PPARG;ENO1 GO:0007611| learning or memory CHRNA7;CNR1;GPI GO:0030199| collagen fibril organization ANXA2;CYP1B1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0034599| cellular response to oxidative stress PRDX1;G6PD;GSR;P4HB;CYCS;SOD1;GPX1;CAT GO:0071230| cellular response to amino acid stimulus HNRNPD;GLRA1 GO:0006695| cholesterol biosynthetic process HMGCR;G6PD GO:0071333| cellular response to glucose stimulus SLC29A1;LGALS1 GO:0030317| sperm motility CACNA1I;GAPDHS GO:0007269| neurotransmitter secretion NAAA;HSPA8 GO:0002576| platelet degranulation TAGLN2;SOD1;ALB;FLNA;ALDOA GO:0009615| response to virus CFL1;CYP1A1;HSPB1;ENO1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NPM1;HNRNPK;PPARG;PLA2G1B;SFPQ GO:0008284| positive regulation of cell proliferation CHRNA7;RPS9;HTR2A;HTR1A;HMGCR;PTGS2;SHMT2;NPM1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:1902177| SOD1;SFPQ GO:0043066| negative regulation of apoptotic process RPS6;ALB;HSPB1;NPM1;HNRNPK;FLNA;GPX1;CAT;RPL10;HMGCR;PTGS2;SOD1;CFL1 GO:0035722| interleukin-12-mediated signaling pathway ANXA2;CFL1;SOD1;P4HB;PPIA;HNRNPA2B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RPL10;SFPQ;TRPV1;TRPV4;ENO1;PPARG;HNRNPA2B1;DDX5 GO:0007155| cell adhesion ZYX;CYP1B1;MYH9 GO:0045087| innate immune response SFPQ;PPARG GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;GPI GO:0043312| neutrophil degranulation TUBB;SRP14;PKM;CAT;ANXA2;ALOX5;EEF1A1;PPIA;ALDOA;PGAM1;HSPA8;IQGAP1;DSP;GPI GO:0046686| response to cadmium ion CAT;GPI GO:0051591| response to cAMP AANAT;LDHA GO:0034220| ion transmembrane transport GLRA3;CHRNA7;CLIC1;GLRA1;TRPA1;TRPV1;GLRB GO:0043200| response to amino acid stimulus GLRA3;CFL1;GLRB GO:0006915| apoptotic process GPX1;LGALS1;GAPDH;CYCS;VDAC1 GO:0030855| epithelial cell differentiation VDAC1;PPARG;PGK1;TAGLN2 GO:0050714| positive regulation of protein secretion PLA2G1B;PPIA GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;PRDX1 GO:0031532| actin cytoskeleton reorganization MYH9;FLNA;TRPV4 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;HSPB1 GO:0001666| response to hypoxia CAT;PKM;CHRNA7;LDHA;CYP1A1 GO:0010977| negative regulation of neuron projection development TRPV4;VIM;LGALS1 GO:0010628| positive regulation of gene expression TRPV4;HNRNPD;VIM GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0043406| positive regulation of MAP kinase activity IQGAP1;HTR2A GO:0048511| rhythmic process AANAT;HNRNPD;SFPQ;DDX5;PPARG GO:0046716| muscle cell homeostasis SOD1;ALDOA GO:0010033| response to organic substance PKM;SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0051262| protein tetramerization SHMT2;CAT;RPS19;HMGCR GO:0045892| negative regulation of transcription, DNA-dependent PPARG;HSPA8;SFPQ;ENO1 GO:0032355| response to estradiol stimulus GPI;CAT;HNRNPD;PTGS2;CYP1A2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process UGT2B7;CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0071456| cellular response to hypoxia NPEPPS;PGK1;PTGS2;P4HB;HP1BP3;OPRD1;SLC29A1 GO:0042593| glucose homeostasis PPARG;GPI;RPS6;TRPV4;CNR1 GO:0002376| immune system process IDO1;SFPQ GO:0031100| organ regeneration PKM;PPARG GO:0006979| response to oxidative stress PRDX1;SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0098869| ALB;GSR;PTGS2;PTGS1;GPX1;CAT GO:0006936| muscle contraction CACNA1H;TPM1;GLRA1 GO:0010041| response to iron(III) ion CYP1A1;G6PD GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;UGT1A9;CYP2C19;CYP2D6 GO:0007605| sensory perception of sound SOD1;GPX1;ALDH7A1 GO:0010629| negative regulation of gene expression HNRNPD;OPRD1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0043524| negative regulation of neuron apoptosis SOD1;GPI GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0045445| myoblast differentiation DDX5;HMGCR;LGALS1 GO:0061614| PPARG;DDX5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;PTGS2;GPX1 GO:0043534| blood vessel endothelial cell migration GPX1;MYH9 GO:0001934| positive regulation of protein phosphorylation ANXA2;CHRNA7 GO:0051289| protein homotetramerization CRYZ;SHMT2;TRPA1;ALDOA;TRPM8;TRPV1;CAT;PKM GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;NPM1 GO:0016032| viral reproduction VIM;HTR2A;HSPA8;NPM1;PPIA;HNRNPK;VDAC1;ZYX GO:0043087| regulation of GTPase activity SOD1;IQGAP1 GO:0042752| regulation of circadian rhythm HNRNPD;PPARG;SFPQ GO:0019430| removal of superoxide radicals SOD1;PRDX1 GO:1902476| GLRA3;CLIC1;GLRA1;GLRB GO:1904706| PPARG;TPM1 GO:0006357| regulation of transcription from RNA polymerase II promoter HNRNPK;DDX5;PPARG;NPM1;PFN1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0008016| regulation of heart contraction CACNA1H;TPM1 GO:0086091| CACNA1G;DSP GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0001525| angiogenesis PTGS2;ANXA2;MYH9;CYP1B1;GPI GO:0045821| positive regulation of glycolysis HTR2A;GAPDHS GO:0045471| response to ethanol G6PD;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0071277| cellular response to calcium ion IQGAP1;ALOX15 GO:0043403| skeletal muscle tissue regeneration GPX1;PKM GO:0051592| response to calcium ion AANAT;HNRNPD GO:0051100| negative regulation of binding CYP2D6 GO:0001889| liver development DDX39B;HNRNPD;PKM;ACAT1;CYP1A1 GO:0006351| transcription, DNA-dependent KHSRP;HNRNPD;SFPQ;SF1;ENO1;DDX5;HNRNPK;EEF1A1;PPARG;HSPA8 GO:0048678| response to axon injury LGALS1;SOD1 GO:0050727| regulation of inflammatory response ZYX;PTGS2 GO:0001659| temperature homeostasis TRPV1;FTO;GPX1;HTR2A GO:0043065| positive regulation of apoptotic process LDHA;SMPD1;PPARG;CYP1B1;TRPV1;RPS6;IDO1;PTGS2;SOD1;CNR1 GO:0042542| response to hydrogen peroxide TRPA1;LDHA;SOD1;CAT;GPX1 GO:0008152| metabolic process ALDH7A1;UGT1A9;PGAM1;SMPD1;PKM;ACAT1;UGT2B7;TPI1 GO:0035556| intracellular signal transduction PLA2G1B;HSPB1 GO:1990776| PTGS2;IQGAP1 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0007399| nervous system development SMPD1;DPYSL2;GLRB GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;G6PD;PLA2G1B;TRPV1;PPARG;CYP2C9;GPX1;UGT2B7;NAAA;PTGS1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0006139| nucleobase-containing compound metabolic process DPYSL2;SLC29A1 GO:0045333| cellular respiration CYCS;CYP1A2 GO:0006811| ion transport TRPV4;GLRB;CACNA1I;VDAC1;ATP5L;TRPV1;TRPM8;CACNA1G;ATP5O;TRPA1;GLRA1;TRPV2;CLIC1;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:2000378| negative regulation of reactive oxygen species metabolic process G6PD;VDAC1 GO:0008283| cell proliferation GPX1;RPL23A;HTR1A;PRDX1;CYP1A1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;LDHA;G6PD;PTGS2;CYP1A2;AANAT;ACAT1 GO:0032868| response to insulin stimulus CAT;PKM;AANAT;TRPV4;SRSF4 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1;CLIC1 GO:0001895| retina homeostasis HSPB1;ALB;PRDX1;SOD1;ACTG1 GO:0034976| response to endoplasmic reticulum stress P4HB;ALOX15 GO:0030336| negative regulation of cell migration CYP1B1;TPM1 GO:0006749| glutathione metabolic process GPX1;CLIC1;SOD1;G6PD;GSR GO:0001890| placenta development SOD1;PPARG;RPS6 GO:0060612| adipose tissue development ACAT1;FTO GO:0048146| positive regulation of fibroblast proliferation ANXA2;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;LDHA GO:0007584| response to nutrient PPARG;LDHA;PKM;CNR1;HMGCR GO:0061844| GAPDH;RPS19;PLA2G1B GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;NPM1;CYP1B1 GO:0019216| regulation of lipid metabolic process UGT1A9;PPARG;CYP1A1;HMGCR;CNR1 GO:0040014| regulation of multicellular organism growth FTO;SOD1 GO:0045454| cell redox homeostasis PRDX1;GSR;GPX1;P4HB GO:0071345| cellular response to cytokine stimulus TRPV1;KHSRP GO:0007520| myoblast fusion CACNA1H;MYH9 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PKM GO:0007601| visual perception GLRA1;CRYZ;OAT;GLRB;CYP1B1 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;CLIC1 GO:0070989| oxidative demethylation CYP2C9;FTO;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0048662| negative regulation of smooth muscle cell proliferation SF1;PPARG GO:0006821| chloride transport GLRB;GLRA1;CLIC1;GLRA3 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0007165| signal transduction DPYSL2;IQGAP1;PLA2G1B;ZYX;CACNA1I;PPARG;GPR18;HNRNPK;SMPD1;NPM1;CHRNA7;CLIC1;LGALS1;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0007420| brain development HNRNPD;ACAT1;DPYSL2 GO:0034644| cellular response to UV PTGS2;NPM1 GO:0045019| negative regulation of nitric oxide biosynthetic process KHSRP;OPRM1 17573:[DB14011 DB01161] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;BCHE;SLC6A3;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0035094| response to nicotine CHRNA7;CNR1;SLC6A3 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GRIN3A;CHRNA10;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0086016| CACNA1G;SCN10A GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;CHRNA10 GO:0007626| locomotory behavior SLC6A3;SOD1;OPRM1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;SLC6A3;TRPM8;CACNA1G;SCN10A;ABCC1;TRPA1 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;HTR3A;SLC6A3 GO:0051591| response to cAMP SLC6A3;AANAT GO:0034220| ion transmembrane transport HTR3A;CHRNA10;GLRB;TRPV1;TRPA1;GLRA1;GRIN3A;CHRNA7;GLRA3 GO:0007568| aging NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CAT;CYP1A1;SLC6A3 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1;HTR3A GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;VDAC1;GLRB;HTR3A;GLRA1;CACNA1G GO:0007595| lactation SLC6A3;SLC29A1 GO:0086010| CACNA1H;CACNA1G;SCN10A;CACNA1I GO:0007600| sensory perception SCN10A;TRPV2;OPRM1 GO:0006816| calcium ion transport CHRNA10;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1;GRIN3A;TRPV2;CHRNA7;TRPV3;CACNA1H GO:0045471| response to ethanol GRIN3A;HTR3A;SLC6A3;HMGCR;OPRM1;CNR1;SOD1;CAT GO:0019233| sensory perception of pain OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1;SCN10A;TRPA1;TRPV1 GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1I;SCN10A;CACNA1G GO:0035725| sodium ion transmembrane transport CACNA1H;SCN10A;CACNA1G;CACNA1I GO:0002027| regulation of heart rate CACNA1G;SCN10A GO:0060078| regulation of postsynaptic membrane potential CHRNA10;CHRNA7 GO:0042136| neurotransmitter biosynthetic process SLC6A3;DAGLA GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CACNA1G;SCN10A;TRPA1;GLRA1;GRIN3A;HTR3A;CHRNA10;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;SLC6A3;PTGS2;CYP1A2;ACAT1;AANAT GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCHE;PPARG;CYP1B1 GO:0042053| regulation of dopamine metabolic process SLC6A3;HTR1A GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN10A;CACNA1G GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;CHRNA10;HTR2A;OPRM1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0007165| signal transduction PLA2G1B;CACNA1I;CHRNA10;HTR3A;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;OPRM1;CACNA1H;TRPV3;TRPM8;TRPV1;TRPV4;CACNA1I;CHRNA10;GRIN3A;TRPA1;CACNA1G GO:0034765| regulation of ion transmembrane transport CACNA1H;CACNA1G;SCN10A;CACNA1I 17574:[DB14011 DB01870] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01870|1,4-dithio-alpha-D-glucopyranose AMY2B common genes common pathways GO:0008152| metabolic process AMY2B;SMPD1;ACAT1 17575:[DB14011 DB07374] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0045471| response to ethanol RPL15;OPRM1;HMGCR;SOD1;CNR1;CAT GO:0008283| cell proliferation HTR1A;RPL23A;GPX1;CYP1A1 GO:0008284| positive regulation of cell proliferation RPL23;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RPL23;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;RPL23;PPARG GO:0010628| positive regulation of gene expression RPL11;RPL23;TRPV4 GO:0007283| spermatogenesis RPL10L;SOD1;CNR1 17576:[DB14011 DB04882] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04882|Edotecarin TOP1 common genes common pathways GO:0016032| viral reproduction VDAC1;HTR2A;TOP1 GO:0048511| rhythmic process TOP1;AANAT;PPARG GO:0042493| response to drug SOD1;HTR2A;TOP1;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2 GO:0007623| circadian rhythm TOP1;AANAT 17577:[DB14011 DB14637] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14637|Fluprednisolone acetate CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0036378| CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1A1;CYP2C9;CRYZ GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 17578:[DB14011 DB06451] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06451|Aprinocarsen PRKCA common genes common pathways GO:0007155| cell adhesion CYP1B1;PRKCA GO:0006915| apoptotic process PRKCA;VDAC1;GPX1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;PRKCA GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;PRKCA;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0035556| intracellular signal transduction PLA2G1B;PRKCA GO:0001525| angiogenesis PTGS2;CYP1B1;PRKCA GO:0050796| regulation of insulin secretion CNR1;PRKCA 17579:[DB14011 DB07207] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways GO:0031667| response to nutrient levels F7;SOD1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;F7;CYP1A1;PPARG;TRPA1 GO:0006919| activation of caspase activity PPARG;F3 GO:0043627| response to estrogen stimulus F7;PPARG GO:0009725| response to hormone stimulus F7;ACAT1 GO:0051897| positive regulation of protein kinase B signaling cascade F7;F3;GPX1 GO:0007623| circadian rhythm AANAT;F7 GO:0045766| positive regulation of angiogenesis CHRNA7;F3;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;F7 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;F7 GO:0031100| organ regeneration F7;PPARG 17580:[DB14011 DB08547] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08547|PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0045087| innate immune response IGHG2;PPARG GO:0002376| immune system process IDO1;IGHG2 17581:[DB14011 DB07488] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07488|{(2Z)-4-AMINO-2-[(4-METHOXYPHENYL)IMINO]-2,3-DIHYDRO-1,3-THIAZOL-5-YL}(4-METHOXYPHENYL)METHANONE CSNK1G3 common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CSNK1G3;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 17582:[DB14011 DB07922] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07922|N-oxo-2-(phenylsulfonylamino)ethanamide MMP12 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;MMP12 GO:0042060| wound healing OPRM1;MMP12;ALOX15 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;MMP12 17583:[DB14011 DB00663] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP2C9;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0002933| CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0036378| CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;TRPV1;TRPV4;PPARG GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0007165| signal transduction GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;NR3C1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4 17584:[DB14011 DB01282] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01282|Carbetocin OXTR common genes common pathways GO:0048565| digestive tract development CYP1A1;OXTR GO:0007595| lactation SLC29A1;OXTR GO:0060137| maternal process involved in parturition OXTR;CYP1A1 GO:0007565| female pregnancy OXTR;IDO1 GO:0007507| heart development PPARG;OXTR GO:0030431| sleep SLC29A1;OXTR;HTR2A;CACNA1I GO:0007166| cell surface receptor linked signaling pathway OXTR;TRPA1;TRPV1 GO:0045777| positive regulation of blood pressure OXTR;CNR1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;OXTR;PPARG;CYP1A1;TRPA1 GO:0042755| eating behavior OXTR;OPRD1;OPRM1 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;OXTR;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0032870| cellular response to hormone stimulus OXTR;CACNA1H GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;OXTR GO:0044849| OXTR;OPRM1 GO:0007613| memory HTR2A;CNR1;OXTR;PTGS2;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OXTR;OPRM1;TRPV1;TRPV4 GO:0043434| response to peptide hormone stimulus TRPV1;OXTR GO:0001975| response to amphetamine CNR2;OXTR;SOD1 GO:0042493| response to drug CAT;SOD1;HTR2A;OXTR;CYP1A2;PTGS2;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0034097| response to cytokine stimulus AANAT;OXTR;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic OXTR;PTGS2 GO:0042220| response to cocaine CNR1;OXTR;OPRM1;SMPD1 GO:0006936| muscle contraction OXTR;CACNA1H;GLRA1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;OXTR GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;OXTR;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG 17585:[DB14011 DB01143] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways GO:0046677| response to antibiotic SOD1;CYP1A1;ALPL GO:0032496| response to lipopolysaccharide ALPL;IDO1;CYP1A1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0030308| negative regulation of cell growth PPARG;ENPP1 GO:0071407| cellular response to organic cyclic compound CYP1B1;ALPL;CYP1A1 GO:0032869| cellular response to insulin stimulus PPARG;ENPP1;PLA2G1B GO:0001649| osteoblast differentiation ALPL;CAT GO:0051384| response to glucocorticoid stimulus PTGS2;ALPL GO:0033280| response to vitamin D PTGS2;ALPL GO:0008152| metabolic process ACAT1;ALPPL2;ALPL;SMPD1;ENPP1 GO:0006955| immune response ENPP1;OPRD1;CNR2 17586:[DB14011 DB02715] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02715|Compound 18 ESR1 common genes common pathways GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV1;TRPV4 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;ESR1;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;ESR1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;ESR1 17587:[DB14011 DB00226] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0006810| transport TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1;SLC6A2 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1;SLC6A2 GO:0048265| response to pain TRPV1;SLC6A2;TRPA1 GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;SLC6A2;ABCC1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GLRB;VDAC1;GLRA1;CACNA1G;SLC6A2 17588:[DB14011 DB01373] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0006919| activation of caspase activity S100A9;S100A8;PDCD6;PPARG GO:0006811| ion transport CACNA1C;ATP2C1;TRPV2;CP;CHRNA7;TRPV3;CACNA1H;GLRA3;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0008283| cell proliferation S100B;GPX1;HTR1A;CYP1A1 GO:0086045| CACNA1G;CACNA1C GO:0010043| response to zinc ion S100A8;AANAT GO:0009791| post-embryonic development BMP4;CYP1A2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;BMP4;PPARG GO:0061844| PLA2G1B;S100A9 GO:0050729| positive regulation of inflammatory response S100A9;S100A8;TRPV4 GO:0051384| response to glucocorticoid stimulus S100B;PTGS2 GO:0001649| osteoblast differentiation CAT;BMP4 GO:0007613| memory PTGS2;HTR2A;CNR1;S100B;CHRNA7 GO:0050796| regulation of insulin secretion CACNA1C;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration CACNA1C;HTR2A;OPRM1;TRPV4;TRPV1 GO:0043010| camera-type eye development BMP4;CYP1A1;CACNA1C GO:0034765| regulation of ion transmembrane transport CACNA1C;CACNA1H;CACNA1I;CACNA1G GO:0070588| calcium ion transmembrane transport CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1H;OPRM1;TRPV3;TRPV2;CACNA1C;ATP2C1;CHRNA7 GO:0065009| regulation of molecular function SPTBN1;TRPV1 GO:0007165| signal transduction CHRNA7;ATP2C1;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0007420| brain development PCDH19;ACAT1 GO:0010629| negative regulation of gene expression BMP4;OPRD1 GO:0001934| positive regulation of protein phosphorylation BMP4;CHRNA7 GO:0006816| calcium ion transport CACNA1H;TRPV3;CHRNA7;TRPV2;CACNA1C;ATP2C1;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;S100A9;S100A8 GO:0006954| inflammatory response S100A8;CNR2;PTGS2;S100A9;ALOX5;PTGS1;TRPV1;ALOX15;IDO1 GO:0010942| positive regulation of cell death PTGS2;BMP4 GO:0006879| cellular iron ion homeostasis ABCG2;CP;SOD1 GO:0086091| CACNA1C;CACNA1G GO:0043401| steroid hormone mediated signaling pathway BMP4;PPARG GO:0051592| response to calcium ion AANAT;CALM1;PDCD6 GO:0045471| response to ethanol HMGCR;OPRM1;S100A8;SOD1;CNR1;CAT GO:0001525| angiogenesis BMP4;PDCD6;CYP1B1;PTGS2 GO:0008152| metabolic process SMPD1;ALPP;ACAT1 GO:0006805| xenobiotic metabolic process CYP2C9;AOC1;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;BMP4;PPARG;S100B;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response PTGS2;S100A8;S100A9 GO:0007507| heart development BMP4;PPARG;CACNA1C GO:0001503| ossification BMP4;ALOX15;MGP GO:0007399| nervous system development SMPD1;GLRB;PCDH19 GO:0002027| regulation of heart rate CALM1;CACNA1G GO:0045165| cell fate commitment BMP4;PPARG GO:0034220| ion transmembrane transport GLRA3;CHRNA7;ATP2C1;GLRA1;TRPA1;TRPV1;GLRB GO:0006915| apoptotic process VDAC1;PDCD6;COMP;GPX1;S100A8;S100A9 GO:0031532| actin cytoskeleton reorganization TRPV4;S100A9;ATP2C1 GO:0045766| positive regulation of angiogenesis CYP1B1;PDCD6;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15;BMP4 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1C;CALM1;CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8 GO:0086002| CACNA1C;CACNA1G GO:0010628| positive regulation of gene expression BMP4;TRPV4 GO:0046688| response to copper ion SOD1;S100A13;AANAT GO:0001657| ureteric bud development CAT;BMP4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;BMP4 GO:0043407| negative regulation of MAP kinase activity SMPD1;BMP4;HMGCR GO:0034605| cellular response to heat PTGS2;PDCD6;TRPV4;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CALM1;PPARG;GPR18 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;BMP4;TRPV1 GO:0030595| leukocyte chemotaxis S100A9;CNR2 GO:0010468| regulation of gene expression CYP1A2;BMP4 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1;S100B GO:0098869| GSR;S100A9;PTGS2;CAT;GPX1;PTGS1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;ATP2C1;GPR12;HTR2A GO:0006936| muscle contraction GLRA1;CALM1;CACNA1H GO:0002376| immune system process IDO1;S100A8;S100A9 GO:0071280| cellular response to copper ion CYP1A2;AOC1;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent BMP4;PPARG GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;AOC1 GO:0030593| neutrophil chemotaxis PLA2G1B;S100A8;S100A9 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;ALOX5;CP;GPX1;PTGS1;AOC1;CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1 GO:0030224| monocyte differentiation BMP4;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;BMP4 GO:0009308| amine metabolic process CYP1A1;AOC1 GO:0007611| learning or memory CNR1;S100B;CHRNA7 GO:0042060| wound healing S100A8;OPRM1;ALOX15 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;S100A8;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0043542| endothelial cell migration CYP1B1;S100A2 GO:0030324| lung development BMP4;CYP1A2 GO:0001822| kidney development BMP4;CAT GO:0043066| negative regulation of apoptotic process BMP4;COMP;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2;BMP4 GO:0002576| platelet degranulation CALM1;SOD1 GO:0046677| response to antibiotic SOD1;AOC1;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;BMP4 GO:0008284| positive regulation of cell proliferation BMP4;HMGCR;PTGS2;HTR2A;HTR1A;S100B;CHRNA7;S100A13 GO:0035307| positive regulation of protein dephosphorylation SMPD1;CALM1 GO:0043312| neutrophil degranulation CAT;ALOX5;S100A9;S100A8;AOC1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;BMP4 GO:0007155| cell adhesion COMP;CYP1B1;PCDH19 GO:0045087| innate immune response S100A9;S100A8;S100B;PPARG 17589:[DB14011 DB01915] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01915|S-Hydroxycysteine C3;GSTP1;ACAT2;GSTA1;PMP2 common genes common pathways GO:0043407| negative regulation of MAP kinase activity SMPD1;GSTP1;HMGCR GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0030855| epithelial cell differentiation VDAC1;GSTA1;PPARG GO:0045766| positive regulation of angiogenesis C3;CHRNA7;CYP1B1 GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0098869| GSR;GSTA1;GSTP1;CAT;PTGS1;GPX1;PTGS2 GO:0002376| immune system process IDO1;C3 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GSTP1;GPR18 GO:0032355| response to estradiol stimulus GSTP1;CAT;PTGS2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;C3;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0006631| fatty acid metabolic process C3;PTGS2;PTGS1;ALOX15 GO:0043312| neutrophil degranulation ALOX5;CAT;C3;GSTP1 GO:0045087| innate immune response C3;PPARG GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;GSTP1 GO:0006695| cholesterol biosynthetic process ACAT2;HMGCR GO:0006635| fatty acid beta-oxidation ACAT2;ACAT1 GO:0034599| cellular response to oxidative stress GSR;GSTP1;CAT;GPX1;SOD1 GO:0000302| response to reactive oxygen species GSTP1;GPX1;CAT;SOD1 GO:0032930| positive regulation of superoxide anion generation SOD1;GSTP1 GO:0006749| glutathione metabolic process GSR;GSTP1;GSTA1;SOD1;GPX1 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0009636| response to toxin GPX1;CAT;GSTP1;CYP1B1;CYP1A1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;C3;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;GSTP1 GO:1904706| GSTP1;PPARG GO:0006955| immune response CNR2;OPRD1;C3 GO:0006954| inflammatory response PTGS2;CNR2;C3;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0001934| positive regulation of protein phosphorylation C3;CHRNA7 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;C3;ACAT2;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;NAAA;GPX1;PTGS1 GO:0008152| metabolic process ACAT1;ACAT2;GSTP1;GSTA1;SMPD1 GO:0006805| xenobiotic metabolic process CYP1B1;GSTP1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;GSTP1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2;C3 17590:[DB14011 DB07593] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07593|1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE CTSK common genes common pathways GO:1903146| VDAC1;CTSK GO:0045453| bone resorption CTSK;GPR55 17591:[DB14011 DB08361] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways GO:0045087| innate immune response SYK;PPARG GO:0030593| neutrophil chemotaxis SYK;PLA2G1B GO:0071404| cellular response to low-density lipoprotein particle stimulus SYK;PPARG GO:0048514| blood vessel morphogenesis SYK;CYP1B1 GO:0002376| immune system process SYK;IDO1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;SYK;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;SYK GO:0001525| angiogenesis PTGS2;CYP1B1;SYK GO:0035556| intracellular signal transduction SYK;PLA2G1B GO:0019370| leukotriene biosynthetic process ALOX5;SYK;PLA2G1B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SYK;HTR2A GO:0016032| viral reproduction VDAC1;SYK;HTR2A GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;SYK;PTGS1;ALOX5;PTGS2;CNR2 GO:0008283| cell proliferation CYP1A1;SYK;GPX1;HTR1A 17592:[DB14011 DB11136] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11136|Chromium CYB5A;TF common genes common pathways GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;TF GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;TF;CACNA1H;GLRA3;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0001895| retina homeostasis SOD1;TF GO:0002576| platelet degranulation SOD1;TF GO:0022900| electron transport chain IDO1;GSR;CYB5A;CYP1A2 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYB5A;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0046686| response to cadmium ion CYB5A;CAT 17593:[DB14011 DB07159] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07159|Tamatinib SYK common genes common pathways GO:0035556| intracellular signal transduction PLA2G1B;SYK GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;SYK GO:0001525| angiogenesis SYK;CYP1B1;PTGS2 GO:0016032| viral reproduction HTR2A;SYK;VDAC1 GO:0006954| inflammatory response SYK;IDO1;ALOX15;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SYK;HTR2A GO:0019370| leukotriene biosynthetic process SYK;PLA2G1B;ALOX5 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1;SYK GO:0045087| innate immune response SYK;PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus SYK;PPARG GO:0030593| neutrophil chemotaxis SYK;PLA2G1B GO:0002376| immune system process IDO1;SYK GO:0048514| blood vessel morphogenesis SYK;CYP1B1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;SYK 17594:[DB14011 DB09209] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes OPRD1;OPRM1 common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRK1;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;CNR2;OPRD1;CNR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0042220| response to cocaine SMPD1;OPRK1;OPRM1;CNR1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0007218| neuropeptide signaling pathway GLRA1;OPRK1;GLRB;GLRA3;OPRM1;OPRD1 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;IDO1 GO:0042060| wound healing OPRM1;ALOX15 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;GLRA1;GLRB;TRPV1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2A;OPRD1;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0032094| response to food CYP1A1;OPRM1 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;TRPV3;CACNA1H;OPRM1;CHRNA7;TRPV2 GO:0044849| OPRM1;OPRK1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;OPRK1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0007610| behavior HTR2A;HTR1A;OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus TRPM8;OPRK1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV4;TRPV1 GO:0071315| cellular response to morphine OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0042755| eating behavior OPRK1;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0032868| response to insulin stimulus OPRK1;TRPV4;CAT;AANAT GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1;CAT GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0045471| response to ethanol OPRK1;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0019233| sensory perception of pain OPRK1;TRPV1;TRPA1;HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1 GO:0006955| immune response OPRK1;OPRD1;CNR2 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0007600| sensory perception OPRM1;TRPV2;OPRK1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;CACNA1G;GLRA1;GLRB;VDAC1;OPRK1 GO:0010629| negative regulation of gene expression OPRD1 GO:0048149| behavioral response to ethanol OPRM1 17595:[DB14011 DB00114] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;BCAT1;HTR1A GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TAT;TRPA1;SRR;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin CYP1B1;CYP1A1;DDC;CAT;GPX1 GO:0009791| post-embryonic development CYP1A2;SGPL1 GO:0051384| response to glucocorticoid stimulus GOT1;AGXT;PTGS2;TAT GO:0040014| regulation of multicellular organism growth SGPL1;SOD1 GO:0019216| regulation of lipid metabolic process ALAS1;CNR1;HMGCR;CYP1A1;PPARG GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0032869| cellular response to insulin stimulus GOT1;PPARG;PLA2G1B GO:0007601| visual perception GLRB;CYP1B1;OAT;GLRA1;CRYZ GO:0007420| brain development SRR;ACAT1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;CACNA1G;GLRA1;GLRB;VDAC1;GAD1;GAD2 GO:0008209| androgen metabolic process CYP3A4;SGPL1 GO:0046219| indolalkylamine biosynthetic process DDC;AANAT GO:0051092| positive regulation of NF-kappaB transcription factor activity CTH;CAT;PLA2G1B GO:0051289| protein homotetramerization SHMT1;CTH;CAT;CRYZ;TRPA1;SHMT2;TRPM8;TRPV1;SRR GO:0006879| cellular iron ion homeostasis ABCG2;ALAS2;SOD1 GO:0046513| ceramide biosynthetic process SPTLC2;SMPD1;SPTLC1 GO:0045471| response to ethanol GOT2;ABAT;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0045776| negative regulation of blood pressure CNR1;ABAT GO:0071312| cellular response to alkaloid TRPV1;DDC GO:0042136| neurotransmitter biosynthetic process DAGLA;GAD2;GAD1 GO:0006778| porphyrin-containing compound metabolic process ALAS2;CYP1A1;ALAS1;CYP1A2 GO:0008152| metabolic process SPTLC2;PYGM;ALAS1;BCAT1;ACAT1;PYGB;PYGL;CBS;SPTLC3;SMPD1;BCAT2;ALAS2;SRR;GCAT;PDXP;FTCD GO:0048148| behavioral response to cocaine ABAT;HTR2A GO:0001503| ossification IGSF10;ALOX15 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;SPTLC2;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;SGPL1;DAGLA;CYP2D6;SPTLC1;ALOX15;SPTLC3;PPARG;CYP2C9 GO:0051591| response to cAMP AGXT;AANAT GO:0006550| isoleucine catabolic process ACAT1;BCAT2 GO:0006915| apoptotic process SGPL1;VDAC1;GPX1 GO:0042220| response to cocaine OPRM1;CNR1;ABAT;SMPD1 GO:0001666| response to hypoxia ABAT;ALAS2;CYP1A1;CHRNA7;CAT GO:0007283| spermatogenesis AZIN2;CNR1;SOD1;SGPL1 GO:0019441| tryptophan catabolic process to kynurenine AADAT;KYNU;IDO1 GO:0051262| protein tetramerization SHMT2;HMGCR;SHMT1;CAT GO:0071363| cellular response to growth factor stimulus OPRD1;DDC;CAT;TRPV1 GO:0006569| tryptophan catabolic process KYNU;IDO1;AADAT GO:0007568| aging ABAT;SRR;CYP1A1;CAT;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD GO:0042593| glucose homeostasis CNR1;TRPV4;PYGL;PPARG GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1;TAT GO:0045429| positive regulation of nitric oxide biosynthetic process AGXT2;TRPV1;PTGS2;OPRM1 GO:0043085| positive regulation of catalytic activity AZIN2;SOD1 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;SRR;GAD1;ABAT;ABCG2;GAD2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15;SGPL1 GO:0022900| electron transport chain GLDC;GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process CBS;CYP1A1;CYP2C9;GLDC;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;PNPO;CAT GO:0008210| estrogen metabolic process CYP1B1;SGPL1 GO:0035640| exploration behavior ABAT;HTR1A GO:0043278| response to morphine OPRM1;CNR1;SRR GO:0009083| branched chain family amino acid catabolic process BCAT2;BCAT1;ACAT1 GO:0035094| response to nicotine CNR1;CHRNA7;ABAT GO:0007623| circadian rhythm AANAT;DDC GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;SRR;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;PDXP;TRPV1 GO:0007269| neurotransmitter secretion GAD1;GAD2;NAAA GO:0033602| negative regulation of dopamine secretion ABAT;CNR1 GO:0009615| response to virus CYP1A1;ODC1 GO:0008284| positive regulation of cell proliferation SHMT2;ODC1;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0007626| locomotory behavior SOD1;OPRM1;ABAT GO:0001822| kidney development CAT;ODC1;SGPL1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;CTH;SOD1 GO:0043312| neutrophil degranulation PYGB;PYGL;ALOX5;CAT 17596:[DB14011 DB02931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes AANAT common pathways GO:0030187| melatonin biosynthetic process AANAT GO:0034695| response to prostaglandin E stimulus AANAT GO:0051591| response to cAMP AANAT GO:0009416| response to light stimulus AANAT GO:0048511| rhythmic process PPARG;AANAT GO:0046688| response to copper ion AANAT;SOD1 GO:0007623| circadian rhythm AANAT GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0009648| photoperiodism AANAT GO:0006474| N-terminal protein amino acid acetylation AANAT GO:0051412| response to corticosterone stimulus AANAT GO:0032868| response to insulin stimulus AANAT;CAT;TRPV4 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;CYP1A2;PTGS2 GO:0010043| response to zinc ion AANAT GO:0051592| response to calcium ion AANAT GO:0046219| indolalkylamine biosynthetic process AANAT GO:0071320| cellular response to cAMP AANAT 17597:[DB14011 DB05513] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05513|Atiprimod IL6;TNF common genes common pathways GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0031622| positive regulation of fever generation CNR1;PTGS2;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;IL6;PPARG;TNF;SMPD1 GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0006954| inflammatory response TNF;IDO1;ALOX15;IL6;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNF;IL6;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG;IL6 GO:0006955| immune response IL6;TNF;CNR2;OPRD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL6 GO:0051384| response to glucocorticoid stimulus PTGS2;TNF;IL6 GO:0050796| regulation of insulin secretion TNF;CNR1 GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;IL6;TNF GO:0006919| activation of caspase activity TNF;PPARG GO:0070301| cellular response to hydrogen peroxide IL6;CYP1B1 GO:0008285| negative regulation of cell proliferation PPARG;IL6;CYP1B1;PTGS2;OPRM1 GO:0042127| regulation of cell proliferation TNF;PTGS2;PTGS1 GO:0071230| cellular response to amino acid stimulus TNF;GLRA1 GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0009615| response to virus TNF;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;PLA2G1B;IL6 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;IL6 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;IL6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;TNF;PPARG GO:0050830| defense response to Gram-positive bacterium PLA2G1B;IL6;TNF GO:0045893| positive regulation of transcription, DNA-dependent IL6;PPARG;TNF GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0046427| positive regulation of JAK-STAT cascade IL6;CYP1B1 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;IL6;HMGCR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0002446| neutrophil mediated immunity PLA2G1B;IL6 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TNF;TRPV1 GO:0032966| negative regulation of collagen biosynthetic process PPARG;IL6 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;TNF;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0000187| activation of MAPK activity PLA2G1B;TNF;CHRNA7;SOD1 GO:0010628| positive regulation of gene expression TRPV4;IL6;TNF GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0010033| response to organic substance TRPA1;TNF;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 17598:[DB14011 DB02269] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02269|[4-({[5-Benzyloxy-1-(3-Carbamimidoyl-Benzyl)-1h-Indole-2-Carbonyl]-Amino}-Methyl)-Phenyl]-Trimethyl-Ammonium PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 17599:[DB14011 DB11091] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes CAT;GPX1 common pathways GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0009642| response to light intensity CAT GO:0051702| interaction with symbiont GPX1 GO:1902176| GPX1 GO:0045444| fat cell differentiation GPX1 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0018158| protein oxidation GPX1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1 GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0033194| response to hydroperoxide GPX1 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0002862| negative regulation of inflammatory response to antigenic stimulus GPX1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;GSR GO:0009410| response to xenobiotic stimulus GPX1 GO:0033197| response to vitamin E CAT GO:0043523| regulation of neuron apoptosis GPX1 GO:0000302| response to reactive oxygen species GPX1;CAT;SOD1 GO:0014902| myotube differentiation GPX1 GO:0008203| cholesterol metabolic process CAT;HMGCR GO:0043312| neutrophil degranulation CAT;ALOX5 GO:0010288| response to lead ion CAT GO:0020027| hemoglobin metabolic process CAT GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0042311| vasodilation GPX1 GO:0001822| kidney development CAT GO:0042744| hydrogen peroxide catabolic process CAT;GPX1 GO:0006915| apoptotic process VDAC1;GPX1 GO:0046686| response to cadmium ion CAT GO:0051262| protein tetramerization CAT;HMGCR GO:0048741| skeletal muscle fiber development GPX1 GO:0010193| response to ozone CAT GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7 GO:0001657| ureteric bud development CAT GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT GO:0007568| aging CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1 GO:0009060| aerobic respiration CAT GO:0009611| response to wounding GPX1;CYP1A1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0007605| sensory perception of sound SOD1;GPX1 GO:0080184| response to phenylpropanoid CAT GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0098869| GSR;GPX1;PTGS1;CAT;PTGS2 GO:0043534| blood vessel endothelial cell migration GPX1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0006195| purine nucleotide catabolic process GPX1 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;GPX1 GO:0033599| regulation of mammary gland epithelial cell proliferation GPX1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B GO:0051289| protein homotetramerization CAT;CRYZ;TRPA1;TRPM8;TRPV1 GO:0043403| skeletal muscle tissue regeneration GPX1 GO:0045471| response to ethanol CNR1;SOD1;OPRM1;HMGCR;CAT GO:0006629| lipid metabolic process PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;NAAA;PTGS1;GPX1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:1902905| GPX1 GO:0008152| metabolic process SMPD1;ALPPL2;ACAT1 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;TRPA1 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0001659| temperature homeostasis TRPV1;HTR2A;GPX1 GO:0033591| response to L-ascorbic acid CAT GO:0040029| regulation of gene expression, epigenetic GPX1 GO:0014854| response to inactivity CAT GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4 GO:0010269| response to selenium ion GPX1 GO:0009636| response to toxin CYP1A1;CYP1B1;GPX1;CAT GO:0009411| response to UV CAT GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;CAT GO:0051450| myoblast proliferation GPX1 GO:0014823| response to activity CAT GO:0001885| endothelial cell development GPX1 GO:1902042| GPX1 GO:0009650| UV protection CAT;GPX1 GO:0006749| glutathione metabolic process GPX1;SOD1;GSR GO:0051781| positive regulation of cell division CAT GO:0009609| response to symbiotic bacterium GPX1 GO:0001649| osteoblast differentiation CAT GO:0045454| cell redox homeostasis GSR;GPX1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1 GO:0070542| response to fatty acid CAT;PTGS2 GO:0010332| response to gamma radiation GPX1 GO:0006641| triglyceride metabolic process GPX1;CAT GO:0061136| regulation of proteasomal protein catabolic process GPX1 GO:0060047| heart contraction GPX1;SOD1 GO:0060055| angiogenesis involved in wound healing GPX1 17600:[DB14011 DB13153] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLCO1B1;SLCO1B3;TRPV3;CACNA1H;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G GO:0055085| transmembrane transport CACNA1H;TRPV3;SLCO1B3;SLCO1B1;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8 17601:[DB14011 DB08340] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08340|N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE CSNK2A1 common genes common pathways GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;CSNK2A1;PTGS2;HTR2A;HTR1A GO:0006915| apoptotic process CSNK2A1;GPX1;VDAC1 GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CSNK2A1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;CSNK2A1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 17602:[DB14011 DB08175] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08175|(2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID NCOA2;RXRB;NR1H3 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NR1H3;PPARG;RXRB;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1H3 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRB;NR1H3 GO:0050728| negative regulation of inflammatory response NR1H3;CNR2 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;NR1H3;NCOA2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRB;PPARG;NR1H3;PLA2G1B GO:0048511| rhythmic process AANAT;NCOA2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0043277| apoptotic cell clearance NR1H3;ALOX15 GO:0042752| regulation of circadian rhythm PPARG;NR1H3 GO:0006351| transcription, DNA-dependent NR1H3;PPARG;RXRB;NCOA2 GO:0043401| steroid hormone mediated signaling pathway RXRB;PPARG;NR1H3 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;NR1H3 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway NR1H3;PPARG GO:0010887| negative regulation of cholesterol storage PPARG;NR1H3 GO:0055088| lipid homeostasis NR1H3;PPARG GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;NCOA2;CYP1A1;PPARG GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H 17603:[DB14011 DB11640] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1;KCNA1;CACNA1H;TRPV3;TRPV2 GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;KCNA1;CACNA1H GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;KCNA1 GO:0050905| neuromuscular process GLRB;KCNA1;GLRA1 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;KCNA1;GLRA1;TRPA1;CACNA1G GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;KCNA1;CACNA1H GO:0007420| brain development ACAT1;KCNA1 GO:0001964| startle response GLRA1;GLRB;KCNA1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain TRPA1;KCNA1;HTR2A GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;GLRA3;CACNA1G;GLRA1;KCNA1;GLRB;VDAC1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;NAT2;CYP2D6;CYP1B1;NAT1 GO:0008152| metabolic process ACAT1;NAT2;NAT1;SMPD1 GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1I;KCNA1;CACNA1G GO:0007405| neuroblast proliferation KCNA1;DAGLA 17604:[DB14011 DB08270] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08270|N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE CTSK common genes common pathways GO:0045453| bone resorption GPR55;CTSK GO:1903146| VDAC1;CTSK 17605:[DB14011 DB02860] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02860|Calyculin A PPP1CC common genes common pathways GO:0048511| rhythmic process PPARG;PPP1CC;AANAT GO:0042752| regulation of circadian rhythm PPP1CC;PPARG 17606:[DB14011 DB00020] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00020|Sargramostim CSF2RA;IL3RA;CSF2RB;SDC2;PRG2 common genes common pathways GO:0002376| immune system process IDO1;PRG2 GO:0032496| response to lipopolysaccharide CYP1A1;CSF2RB;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0043312| neutrophil degranulation CAT;PRG2;ALOX5 GO:0001523| retinoid metabolic process SDC2;NAPEPLD GO:0065009| regulation of molecular function CSF2RA;CSF2RB;TRPV1;IL3RA GO:0007165| signal transduction OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;CSF2RB;PPARG;PLA2G1B;CACNA1I GO:0032693| negative regulation of interleukin-10 production PRG2;IDO1 GO:0006955| immune response OPRD1;CNR2;PRG2 GO:0007399| nervous system development GLRB;SDC2;SMPD1 17607:[DB14011 DB03193] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes common pathways GO:0042060| wound healing OPRM1;PPARA;ALOX15 GO:0036151| PLA2G1B;PLA2G2D GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PPARA GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2D GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TRPV4;TRPV1 GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;FABP3;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0006631| fatty acid metabolic process PTGS2;PPARA;PTGS1;FABP3;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0015909| long-chain fatty acid transport PPARG;FABP3 GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0098869| GSR;ALB;CAT;GPX1;PTGS1;PTGS2 GO:0036152| PLA2G1B;PLA2G2D GO:0016042| lipid catabolic process PLA2G2D;NAPEPLD;DAGLA;PLA2G1B GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;PPARA GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0042130| negative regulation of T cell proliferation IDO1;PLA2G2D GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G2D;PLA2G1B GO:0036149| PLA2G1B;PLA2G2D GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0006351| transcription, DNA-dependent PPARG;PPARA GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0036148| PLA2G2D;PLA2G1B GO:0007507| heart development PPARA;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;PLA2G2D;NAPEPLD;CYP3A4;PPARA;PTGS1;NAAA;GPX1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;PLA2G2D;CNR2;PTGS2 GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0019216| regulation of lipid metabolic process PPARA;CNR1;HMGCR;CYP1A1;PPARG GO:0050482| arachidonic acid secretion PLA2G2D;PLA2G1B GO:0070542| response to fatty acid FABP3;CAT;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0032868| response to insulin stimulus TRPV4;FABP3;PPARA;CAT;AANAT GO:0001895| retina homeostasis ALB;SOD1 GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0036150| PLA2G2D;PLA2G1B GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;FABP3;CYP1B1;PPARG 17608:[DB14011 DB02258] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02258|SR11254 RARG common genes common pathways GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0010628| positive regulation of gene expression TRPV4;RARG GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;RARG;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process CAT;RARG;GPX1;SOD1;PTGS2;HMGCR GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;TRPV4;TRPV1;PPARG GO:0032526| response to retinoic acid PPARG;RARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0043010| camera-type eye development CYP1A1;RARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;RARG GO:0043065| positive regulation of apoptotic process RARG;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0006351| transcription, DNA-dependent PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG 17609:[DB14011 DB11569] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11569|Ixekizumab IL17A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IL17A;PPARG GO:0008219| cell death IL17A;HTR2A GO:0006915| apoptotic process GPX1;VDAC1;IL17A GO:2000778| positive regulation of interleukin-6 secretion TRPV4;IL17A GO:0006954| inflammatory response IL17A;TRPV1;ALOX15;IDO1;PTGS2;CNR2;ALOX5;PTGS1 GO:0006955| immune response CNR2;OPRD1;IL17A 17610:[DB14011 DB06345] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06345|AR-9281 EPHX2 common genes common pathways GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;EPHX2;TRPV1;IDO1;ALOX15 GO:0008152| metabolic process SMPD1;ACAT1;EPHX2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;EPHX2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;EPHX2;PTGS1;NAAA;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0009636| response to toxin EPHX2;GPX1;CAT;CYP1A1;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS2;EPHX2;SOD1;PTGS1 GO:0072593| reactive oxygen species metabolic process SOD1;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2;EPHX2 GO:0010628| positive regulation of gene expression TRPV4;EPHX2 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;EPHX2;TRPM8;TRPV4 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;EPHX2;CYP3A4;CYP1A2 17611:[DB14011 DB08738] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08738|1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one PREP common genes common pathways 17612:[DB14011 DB01130] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0006915| apoptotic process NR3C1;GPX1;VDAC1 GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PLA2G1B;PPARG GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;NR3C1;CHRNA7 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 17613:[DB14011 DB06151] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0008344| adult locomotory behavior OPRD1;GRIN1;GRIN2D GO:0009636| response to toxin CAT;GPX1;CHUK;SLC7A11;CYP1B1;CYP1A1 GO:0051930| regulation of sensory perception of pain GRIN2A;OPRD1;OPRM1;GRIN2D GO:0006811| ion transport TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;GLRA1;TRPA1;GRIN3A;CACNA1G;CHRNA7;GRIN2A;TRPV2;SLCO1B1;GLRA3;GRIN2B;TRPV3;CACNA1H;GRIN1;GRIN2D GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CHUK;CYP1B1 GO:0098656| VDAC1;SLC22A6 GO:0006812| cation transport GRIN1;TRPM8 GO:0071276| cellular response to cadmium ion CHUK;CYP1A2;SOD1 GO:0022008| neurogenesis GRIN2A;DAGLA GO:0007613| memory GRIN2A;CHRNA7;PTGS2;GRIN1;HTR2A;CNR1 GO:0043576| regulation of respiratory gaseous exchange GLRA1;GRIN1 GO:0001975| response to amphetamine GRIN2A;SOD1;GRIN1;CNR2 GO:0065009| regulation of molecular function TRPV1;GRIN2D;GRIN1;GRIN2B;GRIN2A GO:0007420| brain development ACAT1;SLC7A11 GO:1900273| CHRNA7;GRIN2A GO:0070588| calcium ion transmembrane transport TRPV3;OPRM1;CACNA1H;CHRNA7;TRPV2;TRPA1;GRIN3A;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4 GO:0031667| response to nutrient levels GSS;SOD1 GO:0007268| synaptic transmission GRIN2A;OPRM1;OPRD1;GRIN2B;HTR2A;GLRA3;GLRB;VDAC1;CACNA1G;GLRA1 GO:0043524| negative regulation of neuron apoptosis SOD1;GRIN1 GO:0008542| visual learning GRIN2A;GRIN1;HMGCR GO:0006955| immune response CHUK;OPRD1;CNR2 GO:0001964| startle response GLRA1;GLRB;GRIN1;GRIN2D;GRIN2A GO:0006816| calcium ion transport CHRNA7;GRIN2A;TRPV2;TRPV3;CACNA1H;GRIN1;TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;GRIN3A;CACNA1G GO:0051092| positive regulation of NF-kappaB transcription factor activity CHUK;CAT;IKBKB;PLA2G1B GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;CHUK;ALOX5;PTGS1;CNR2;PTGS2;IKBKB GO:0030431| sleep CACNA1I;HTR2A;SLC29A1;GRIN2A GO:0019233| sensory perception of pain TRPV1;TRPA1;GRIN2A;OPRM1;GRIN1;PTGS2;CNR2;OPRD1;CNR1;HTR2A GO:0045471| response to ethanol GRIN3A;CAT;GRIN2A;GRIN1;OPRM1;HMGCR;GRIN2B;SOD1;CNR1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GRIN2A GO:0007399| nervous system development GSS;GLRB;SMPD1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;ACY1;CYP3A7;CYP1A2;CYP3A4 GO:0008152| metabolic process ACAT1;ACY1;SMPD1 GO:0042428| serotonin metabolic process HTR1A;GRIN2A GO:0043065| positive regulation of apoptotic process SOD1;CNR1;GRIN1;PTGS2;GRIN2A;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0034612| response to tumor necrosis factor PTGS2;GSS GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;SLC22A6;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLCO1B1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;GRIN3A;TRPV1;GLRB GO:0043200| response to amino acid stimulus GSS;GLRB;GLRA3;CHUK GO:0046686| response to cadmium ion CAT;GSS GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CHUK;CYP1A2;PTGS2;SOD1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN1 GO:0071356| cellular response to tumor necrosis factor CHUK;IKBKB;TRPV1 GO:0007568| aging CYP1A1;GSS;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CAT GO:0006810| transport GRIN2A;TRPV2;GRIN2B;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0009611| response to wounding GPX1;GRIN2A;CYP1A1 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;SLC7A11;GSS GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;GRIN1;CHRNA7;TRPM8;TRPV4 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;GRIN2A;CACNA1H;GRIN1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0045893| positive regulation of transcription, DNA-dependent CHUK;IKBKB;PPARG GO:0050905| neuromuscular process GRIN1;GLRA1;GLRB GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT;GRIN2A;CHUK GO:0043278| response to morphine GRIN1;OPRM1;CNR1 GO:0035094| response to nicotine CNR1;SLC7A11;CHRNA7 GO:0033194| response to hydroperoxide GPX1;CHUK GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2D;GRIN1;OPRM1;GLRA3;GRIN2B;SLC29A1;GRIN2A;CHRNA7;GLRA1;GRIN3A;GLRB;TRPV1 GO:0043523| regulation of neuron apoptosis GPX1;GRIN1 GO:0009410| response to xenobiotic stimulus GSS;GPX1 GO:0007611| learning or memory CHRNA7;GRIN2A;CNR1;GRIN2B;GRIN1 GO:0007612| learning VDAC1;GRIN1;PTGS2;GRIN2A GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2;CHUK GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B;GRIN1 GO:0045087| innate immune response PPARG;CHUK;IKBKB GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;IKBKB GO:0009615| response to virus CYP1A1;IKBKB;CHUK GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;IKBKB;CHUK;PPARG;PLA2G1B 17614:[DB14011 DB07125] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07125|4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid DAPK3 common genes common pathways GO:0043065| positive regulation of apoptotic process DAPK3;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0035556| intracellular signal transduction PLA2G1B;DAPK3 GO:0006351| transcription, DNA-dependent DAPK3;PPARG GO:0006915| apoptotic process DAPK3;GPX1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;DAPK3 17615:[DB14011 DB03704] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0045777| positive regulation of blood pressure CNR1;ADH5 GO:0001523| retinoid metabolic process NAPEPLD;ADH5 GO:0032496| response to lipopolysaccharide CYP1A1;ADH5;IDO1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;ADH5 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;ADH5;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT 17616:[DB14011 DB06634] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06634|Casopitant CYP3A4;TACR1 common genes CYP3A4 common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;TACR1 GO:0008217| regulation of blood pressure PPARG;TACR1;PTGS2;SOD1;PTGS1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;PTGS2;TACR1;CYP1A2 GO:0042755| eating behavior TACR1;OPRM1;OPRD1 GO:0045777| positive regulation of blood pressure TACR1;CNR1 GO:0045907| positive regulation of vasoconstriction HTR2A;TACR1;PTGS2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0009725| response to hormone stimulus TACR1;ACAT1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;TACR1;CNR2 GO:0060083| smooth muscle contraction involved in micturition TACR1;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;TACR1;OPRM1;TRPV4;TRPV1 GO:0043117| positive regulation of vascular permeability TRPV4;TACR1 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;TACR1;PTGS2;CNR2;ALOX5;PTGS1 GO:0009408| response to heat TRPV1;TRPV2;SOD1;TACR1;TRPV3 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;TACR1;OPRD1;GLRA1;CACNA1G;GLRB;VDAC1 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;GPX1;PTGS1 GO:0048266| behavioral response to pain TRPV1;TACR1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0019233| sensory perception of pain TACR1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPA1;TRPV1 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;TACR1 GO:0010193| response to ozone TACR1;CAT GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP1A1 GO:0036378| CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;TACR1;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;GPR18;PPARG GO:0032355| response to estradiol stimulus TACR1;PTGS2;CYP1A2;CAT GO:0035094| response to nicotine CHRNA7;TACR1;CNR1 GO:0043278| response to morphine TACR1;OPRM1;CNR1 GO:0048265| response to pain TACR1;TRPV1;TRPA1 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0007611| learning or memory TACR1;CNR1;CHRNA7 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;TACR1;OPRM1;HTR2A 17617:[DB14011 DB05024] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0001649| osteoblast differentiation CAT;CYP24A1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;VDR;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0033280| response to vitamin D PTGS2;CYP24A1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;VDR;PPARG;CYP1B1 GO:0006351| transcription, DNA-dependent PPARG;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG GO:0007595| lactation SLC29A1;VDR GO:0006816| calcium ion transport TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;VDR;TRPV2;CHRNA7;TRPV3;CACNA1H GO:0046697| decidualization PTGS2;VDR GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CHRNA7;VDR;TRPM8;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG GO:0042359| vitamin D metabolic process CYP1A1;CYP24A1;CYP3A4 GO:0010628| positive regulation of gene expression VDR;TRPV4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;PPARG;PLA2G1B GO:0055114| oxidation-reduction process CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;CYP24A1;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0006355| regulation of transcription, DNA-dependent VDR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter VDR;PPARG 17618:[DB14011 DB09488] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09488|Acrivastine HRH1 common genes common pathways GO:0007613| memory CHRNA7;CNR1;HTR2A;HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;HRH1;CHRNA7 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ALOX5;PTGS1;PTGS2;CNR2;HRH1 GO:0008542| visual learning HRH1;HMGCR GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;HRH1;PPARG;GPR18 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;HRH1;OPRD1;OPRM1 17619:[DB14011 DB08869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08869|Tesamorelin GHRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;GHRHR;PPARG GO:0008284| positive regulation of cell proliferation GHRHR;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0071333| cellular response to glucose stimulus GHRHR;SLC29A1 GO:0007165| signal transduction SMPD1;GHRHR;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 GO:0032869| cellular response to insulin stimulus PLA2G1B;GHRHR;PPARG GO:0051384| response to glucocorticoid stimulus PTGS2;GHRHR GO:0043627| response to estrogen stimulus PPARG;GHRHR GO:0032868| response to insulin stimulus GHRHR;TRPV4;AANAT;CAT GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;GHRHR GO:0007166| cell surface receptor linked signaling pathway TRPV1;GHRHR;TRPA1 GO:0048469| cell maturation GHRHR;PPARG GO:0007595| lactation SLC29A1;GHRHR 17620:[DB14011 DB08676] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08676|(20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;FNTB;PTGS1 17621:[DB14011 DB03509] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03509|2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide PARP1 common genes common pathways GO:0006915| apoptotic process GPX1;PARP1;VDAC1 GO:0034599| cellular response to oxidative stress GPX1;CAT;PARP1;SOD1;GSR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;TRPV4;TRPV1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PARP1 GO:0006355| regulation of transcription, DNA-dependent PPARG;PARP1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PARP1 GO:0010332| response to gamma radiation PARP1;GPX1 GO:0006351| transcription, DNA-dependent PARP1;PPARG GO:0071294| cellular response to zinc ion PARP1;GLRA1 17622:[DB14011 DB07465] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0007155| cell adhesion DPP4;CYP1B1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A 17623:[DB14011 DB02069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02069|N-(2-Flouro-Benzyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0001822| kidney development CAT;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 17624:[DB14011 DB03507] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways GO:0007165| signal transduction TNFRSF1A;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0050729| positive regulation of inflammatory response TNFRSF1A;TRPV4 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;TNFRSF1A;ALOX5;PTGS1;CNR2;PTGS2 GO:0016032| viral reproduction HTR2A;TNFRSF1A;VDAC1 GO:0006955| immune response TNFRSF1A;CNR2;OPRD1 GO:0071260| cellular response to mechanical stimulus TNFRSF1A;PTGS2 GO:0006693| prostaglandin metabolic process TNFRSF1A;PTGS1;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TNFRSF1A;TRPA1 GO:0006915| apoptotic process TNFRSF1A;VDAC1;GPX1 GO:0050728| negative regulation of inflammatory response CNR2;TNFRSF1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFRSF1A;PLA2G1B GO:0042127| regulation of cell proliferation TNFRSF1A;PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;TNFRSF1A;IDO1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 17625:[DB14011 DB07662] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07662|N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE SRC;EGFR common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;EGFR GO:0001889| liver development EGFR;CYP1A1;ACAT1 GO:0051592| response to calcium ion EGFR;AANAT GO:0006970| response to osmotic stress TRPV4;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0001503| ossification ALOX15;EGFR GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0042542| response to hydrogen peroxide TRPA1;SRC;GPX1;CAT;SOD1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SRC;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0035556| intracellular signal transduction SRC;EGFR;PLA2G1B GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0031667| response to nutrient levels SRC;SOD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0007165| signal transduction GPR18;PPARG;SMPD1;EGFR;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;SRC GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;EGFR GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0045453| bone resorption SRC;GPR55 GO:0045907| positive regulation of vasoconstriction EGFR;HTR2A;PTGS2 GO:0008283| cell proliferation EGFR;CYP1A1;SRC;GPX1;HTR1A GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;EGFR;TRPA1;CYP1A1;PPARG GO:0032930| positive regulation of superoxide anion generation SOD1;EGFR GO:0071276| cellular response to cadmium ion EGFR;SOD1;CYP1A2 GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication EGFR;PLA2G1B GO:0071230| cellular response to amino acid stimulus GLRA1;EGFR GO:0030324| lung development EGFR;CYP1A2 GO:0042127| regulation of cell proliferation EGFR;SRC;PTGS1;PTGS2 GO:0042060| wound healing ALOX15;EGFR;OPRM1 GO:0007623| circadian rhythm EGFR;AANAT GO:0007611| learning or memory CNR1;CHRNA7;EGFR GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process EGFR;SOD1;PTGS2;HMGCR;CAT;GPX1;SRC GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;SRC;HTR2A;SOD1;PTGS2;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;GPX1;SRC GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;HMGCR;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;EGFR;TRPV1 GO:0032355| response to estradiol stimulus EGFR;CAT;CYP1A2;PTGS2 GO:0002376| immune system process IDO1;SRC GO:0033993| response to lipid EGFR;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;EGFR;OPRM1;PTGS2 GO:0006979| response to oxidative stress EGFR;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;SRC;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0007202| activation of phospholipase C activity HTR2A;GPR55;EGFR GO:0010628| positive regulation of gene expression TRPV4;SRC 17626:[DB14011 DB06422] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06422|Ticalopride HTR4;HTR3A common genes common pathways GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;HTR4;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;HTR3A;SMPD1;PPARG;GPR18 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;HTR3A;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0045471| response to ethanol HTR3A;SOD1;CNR1;OPRM1;HMGCR;CAT GO:0007268| synaptic transmission HTR3A;GLRB;VDAC1;GLRA1;CACNA1G;HTR2A;GLRA3;OPRD1;OPRM1;HTR4 GO:0071363| cellular response to growth factor stimulus HTR3A;TRPV1;OPRD1;CAT GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;HTR4;OPRM1;OPRD1 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;HTR3A GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;TRPV1;GLRB;HTR3A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;HTR4;CNR2;OPRM1 17627:[DB14011 DB05869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways GO:0006919| activation of caspase activity TNF;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;HMGB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;HMGB1;TRPV4;TRPV1 GO:0050796| regulation of insulin secretion TNF;CNR1 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;TNF GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF GO:0010629| negative regulation of gene expression OPRD1;TNF GO:2000778| positive regulation of interleukin-6 secretion HMGB1;TRPV4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;PLA2G1B;CAT GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;IDO1;HMGB1;ALOX15;TRPV1;TNF GO:0006955| immune response CNR2;OPRD1;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation PTGS2;CNR1;TNF GO:0006357| regulation of transcription from RNA polymerase II promoter HMGB1;PPARG GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;TNF;SMPD1;IDO1;HMGB1;CYP1B1;TRPV1 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;HMGB1;ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;TNF GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;TNF;TRPA1 GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG GO:0010628| positive regulation of gene expression TRPV4;TNF GO:0043277| apoptotic cell clearance ALOX15;HMGB1 GO:0032735| positive regulation of interleukin-12 production HMGB1;IDO1 GO:0002376| immune system process HMGB1;IDO1 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TRPV1;OPRM1;PTGS2 GO:0043388| positive regulation of DNA binding PPARG;HMGB1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2;HMGCR GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0046330| positive regulation of JNK cascade HMGB1;TRPV4;TNF GO:0042127| regulation of cell proliferation PTGS2;PTGS1;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;HMGB1;TNF;PPARG GO:0045087| innate immune response HMGB1;PPARG GO:0043312| neutrophil degranulation CAT;ALOX5;HMGB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;HMGB1;TNF;PPARG GO:0009615| response to virus TNF;CYP1A1 17628:[DB14011 DB01629] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01629|5-Fluorouridine SOD1 common genes SOD1 common pathways GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;TRPA1 GO:0008090| retrograde axon cargo transport SOD1 GO:0000303| response to superoxide SOD1 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0045471| response to ethanol SOD1;CNR1;OPRM1;HMGCR;CAT GO:0019226| transmission of nerve impulse SOD1 GO:0043087| regulation of GTPase activity SOD1 GO:0009408| response to heat TRPV1;TRPV2;SOD1;TRPV3 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 GO:0019430| removal of superoxide radicals SOD1 GO:0031667| response to nutrient levels SOD1 GO:0045859| regulation of protein kinase activity SOD1 GO:0043524| negative regulation of neuron apoptosis SOD1 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0001819| positive regulation of cytokine production SOD1 GO:0060047| heart contraction SOD1;GPX1 GO:0040014| regulation of multicellular organism growth SOD1 GO:0007566| embryo implantation PTGS2;SOD1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0002262| myeloid cell homeostasis SOD1 GO:0001890| placenta development SOD1;PPARG GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0006749| glutathione metabolic process GPX1;SOD1;GSR GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0032930| positive regulation of superoxide anion generation SOD1 GO:0046620| regulation of organ growth SOD1 GO:0001895| retina homeostasis SOD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:1902177| SOD1 GO:0035722| interleukin-12-mediated signaling pathway SOD1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0002576| platelet degranulation SOD1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0007626| locomotory behavior SOD1;OPRM1 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1 GO:0097332| SOD1 GO:0034599| cellular response to oxidative stress GSR;SOD1;GPX1;CAT GO:0006801| superoxide metabolic process SOD1 GO:0034465| response to carbon monoxide SOD1 GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0007569| cell aging SOD1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0048538| thymus development SOD1 GO:0007605| sensory perception of sound SOD1;GPX1 GO:0043085| positive regulation of catalytic activity SOD1 GO:0042554| superoxide anion generation SOD1 GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CYP1A1 GO:0046688| response to copper ion AANAT;SOD1 GO:0007283| spermatogenesis SOD1;CNR1 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0046716| muscle cell homeostasis SOD1 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7 GO:0001541| ovarian follicle development SOD1 17629:[DB14011 DB12478] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;DRD2;HTR2A GO:0007186| G-protein coupled receptor signaling pathway GPR18;DRD3;PPARG;DRD2;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0006874| cellular calcium ion homeostasis DRD3;TRPM8;DRD2;TRPV4;GPR12;HTR2A;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;DRD2;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0042220| response to cocaine DRD2;SMPD1;DRD3;OPRM1;CNR1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DRD2 GO:0009416| response to light stimulus AANAT;DRD2 GO:0014059| regulation of dopamine secretion DRD3;DRD2;HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD2;GPR18;GPR55 GO:0007612| learning PTGS2;VDAC1;DRD3 GO:0007611| learning or memory DRD3;CNR1;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;DRD2;GLRB;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0008284| positive regulation of cell proliferation DRD3;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0007626| locomotory behavior DRD3;DRD2;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;DRD3;PPARG GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;OPRM1 GO:0007628| adult walking behavior GLRA1;DRD2;GLRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;DRD3;TRPV1;TRPV4 GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;DRD3;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;DRD2 GO:0043278| response to morphine DRD3;DRD2;CNR1;OPRM1 GO:0035094| response to nicotine CNR1;CHRNA7;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0040014| regulation of multicellular organism growth SOD1;DRD3 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;DRD3;CNR1;HMGCR GO:0001975| response to amphetamine DRD2;DRD3;CNR2;SOD1 GO:0050482| arachidonic acid secretion DRD3;PLA2G1B;DRD2 GO:1900273| CHRNA7;DRD2 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CACNA1I;DRD2;PLA2G1B;PPARG;DRD3;GPR18;SMPD1 GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0009636| response to toxin CAT;GPX1;DRD2;CYP1B1;CYP1A1 GO:0014854| response to inactivity DRD2;CAT GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;DRD2;CYP1B1;PPARG GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0045471| response to ethanol DRD2;DRD3;CAT;HMGCR;OPRM1;SOD1;CNR1 GO:0045776| negative regulation of blood pressure CNR1;DRD3;DRD2 GO:0048678| response to axon injury SOD1;DRD2 GO:0001659| temperature homeostasis TRPV1;DRD2;HTR2A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0048148| behavioral response to cocaine HTR2A;DRD2;DRD3 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0001964| startle response GLRA1;DRD2;GLRB GO:0008542| visual learning HMGCR;DRD2;DRD3 17630:[DB14011 DB02936] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02936|4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid PLA2G2A common genes common pathways GO:0036149| PLA2G1B;PLA2G2A GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;PLA2G2A;ALOX15;CYP2C9;PPARG;PTGS1;NAAA;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4 GO:0036148| PLA2G1B;PLA2G2A GO:0036150| PLA2G2A;PLA2G1B GO:0050729| positive regulation of inflammatory response TRPV4;PLA2G2A GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2A GO:0050830| defense response to Gram-positive bacterium PLA2G1B;PLA2G2A GO:0036151| PLA2G2A;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2A GO:0016042| lipid catabolic process NAPEPLD;DAGLA;PLA2G2A;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;PLA2G2A;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;PLA2G2A GO:0036152| PLA2G2A;PLA2G1B 17631:[DB14011 DB02148] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02148|3-Amino-4-Oxybenzyl-2-Butanone CTSB common genes common pathways GO:0030855| epithelial cell differentiation VDAC1;CTSB;PPARG GO:0046697| decidualization CTSB;PTGS2 GO:0043312| neutrophil degranulation CAT;ALOX5;CTSB GO:0046718| entry of virus into host cell HTR2A;CTSB 17632:[DB14011 DB02449] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02449|3-(1h-Indol-3-Yl)-2-[4-(4-Phenyl-Piperidin-1-Yl)-Benzenesulfonylamino]-Propionic Acid MMP3 common genes common pathways 17633:[DB14011 DB02335] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02335|2-Aminothiazoline NOS3 common genes common pathways GO:0042311| vasodilation NOS3;GPX1 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development NOS3;CYP1A2 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2C19;GSR;IDO1;CYP2D6;NOS3;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;GPX1;PTGS1 GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 GO:0001525| angiogenesis PTGS2;NOS3;CYP1B1 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;NOS3 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0045454| cell redox homeostasis GPX1;GSR;NOS3 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;NOS3;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;NOS3;CYP1B1 GO:1902042| NOS3;GPX1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 17634:[DB14011 DB07387] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07387|3-(BUTYLSULPHONYL)-PROPANOIC ACID TPI1 common genes common pathways GO:0008152| metabolic process TPI1;ACAT1;SMPD1 17635:[DB14011 DB01021] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0008217| regulation of blood pressure PTGS2;ATP1A1;SOD1;PTGS1;PPARG GO:0006811| ion transport GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;SLC12A3;CHRNA7;CACNA1H;TRPV3;GLRA3;ATP1A1 GO:0006139| nucleobase-containing compound metabolic process TPMT;SLC29A1 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SLC12A3;CACNA1H GO:1902476| GLRB;GLRA1;SLC12A3;GLRA3 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0006810| transport SLC12A3;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CA2;PPARG;CYP1A1;TRPA1 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;GLRA3;ATP1A1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2;SLC12A3 GO:0086002| ATP1A1;CACNA1G GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0001822| kidney development CAT;CA2 GO:0032259| methylation TPMT;CYP1A2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;ATP1A1;CYP1A2;PTGS2 17636:[DB14011 DB00824] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0031000| response to caffeine PPARG;ADORA2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0001666| response to hypoxia CAT;CHRNA7;ADORA1;CYP1A1 GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0000187| activation of MAPK activity ADORA2B;PLA2G1B;CHRNA7;SOD1 GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0006915| apoptotic process ADORA2A;VDAC1;GPX1 GO:0016042| lipid catabolic process NAPEPLD;ADORA1;DAGLA;PLA2G1B GO:0097756| PTGS2;HMGCR;ADORA1 GO:0007186| G-protein coupled receptor signaling pathway PDE4B;ADORA2B;PPARG;ADORA1;GPR18;ADORA3;ADORA2A;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;PDE4A;OPRD1 GO:0009611| response to wounding CYP1A1;ADORA3;GPX1 GO:0051967| negative regulation of synaptic transmission, glutamatergic ADORA1;HTR2A GO:0050728| negative regulation of inflammatory response ADORA2A;ADORA1;CNR2 GO:0060087| relaxation of vascular smooth muscle ADORA1;ADORA2B;SOD1 GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4B GO:0006355| regulation of transcription, DNA-dependent PPARG;ADORA2A GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ADORA2A GO:0035307| positive regulation of protein dephosphorylation ADORA1;SMPD1 GO:0007626| locomotory behavior SOD1;OPRM1;ADORA2A GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;ADORA1 GO:0042311| vasodilation ADORA2A;GPX1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;ADORA1;GLRA1;ADORA2A;CHRNA7;SLC29A1;GLRA3;OPRM1 GO:0008285| negative regulation of cell proliferation ADORA1;PPARG;ADORA3;ADORA2A;CYP1B1;PTGS2;OPRM1 GO:0030336| negative regulation of cell migration ADORA3;CYP1B1 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;SOD1;OPRD1 GO:0045777| positive regulation of blood pressure CNR1;ADORA1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;ADORA3;CYP1B1 GO:0032229| negative regulation of synaptic transmission, GABAergic CNR2;ADORA1 GO:0042755| eating behavior ADORA2A;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain ADORA1;OPRM1;OPRD1 GO:0007165| signal transduction ADORA2B;CACNA1I;PLA2G1B;PDE4B;SMPD1;ADORA3;ADORA2A;GPR18;ADORA1;PPARG;CHRNA7;PDE4A;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADORA1;OPRD1;OPRM1 GO:0050890| cognition ADORA1;CHRNA7 GO:0001975| response to amphetamine SOD1;CNR2;ADORA2A GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;ADORA1;HTR2A GO:0007600| sensory perception TRPV2;OPRM1;ADORA2A GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;ADORA2A;ADORA3;ADORA1;TRPV1;IDO1;ALOX15 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;ADORA2A GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0007399| nervous system development SMPD1;ADORA1;GLRB GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADORA2A GO:0001659| temperature homeostasis ADORA1;TRPV1;HTR2A;GPX1 GO:0045776| negative regulation of blood pressure ADORA1;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;ADORA2B;PTGS2 GO:0008016| regulation of heart contraction ADORA3;CACNA1H 17637:[DB14011 DB03175] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03175|Propyl alcohol LYZ common genes common pathways GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LYZ GO:0043312| neutrophil degranulation ALOX5;CAT;LYZ GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;IDO1;ALOX15;LYZ;TRPV1 GO:0008152| metabolic process ACAT1;SMPD1;LYZ GO:0001895| retina homeostasis SOD1;LYZ 17638:[DB14011 DB11834] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11834|Guselkumab IL23A common genes common pathways GO:0032693| negative regulation of interleukin-10 production IL23A;IDO1 GO:0006955| immune response IL23A;CNR2;OPRD1 GO:0006954| inflammatory response PTGS2;CNR2;IL23A;ALOX5;PTGS1;TRPV1;IDO1;ALOX15 GO:0050729| positive regulation of inflammatory response TRPV4;IL23A GO:0045087| innate immune response IL23A;PPARG GO:0035722| interleukin-12-mediated signaling pathway IL23A;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;IL23A GO:0032735| positive regulation of interleukin-12 production IL23A;IDO1 GO:0002376| immune system process IDO1;IL23A 17639:[DB14011 DB02318] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02318|2-deoxy-2-fluoro-alpha-D-mannosyl fluoride MAN2A1 common genes common pathways GO:0008152| metabolic process SMPD1;MAN2A1;ACAT1 GO:0001889| liver development ACAT1;MAN2A1;CYP1A1 GO:0050769| positive regulation of neurogenesis OPRM1;MAN2A1 17640:[DB14011 DB02546] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0034605| cellular response to heat HDAC2;PTGS2;TRPV4;TRPV1 GO:1903146| VDAC1;HDAC6 GO:0010977| negative regulation of neuron projection development TRPV4;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent HDAC1;PPARG;HDAC3;HDAC2;HDAC6 GO:0031000| response to caffeine HDAC2;PPARG;HDAC1 GO:0010033| response to organic substance HDAC6;SOD1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0048714| positive regulation of oligodendrocyte differentiation HDAC1;PPARG;HDAC2 GO:0048511| rhythmic process HDAC1;PPARG;AANAT;HDAC2 GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC1 GO:0042220| response to cocaine CNR1;OPRM1;HDAC2;SMPD1 GO:0043066| negative regulation of apoptotic process HDAC1;HDAC2;CAT;HDAC3;GPX1;SOD1;PTGS2;HMGCR GO:0071300| cellular response to retinoic acid HDAC2;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HDAC2;HMGCR;PTGS2;HTR2A;HTR1A;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;PPARG;PLA2G1B;HDAC3;HDAC2 GO:0070848| response to growth factor stimulus OPRM1;HDAC6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;HDAC2;HDAC3;TRPV4;TRPV1;PPARG;HDAC1 GO:0032496| response to lipopolysaccharide HDAC2;CNR1;CYP1A2;OPRM1;PTGS2;CNR2;IDO1;CYP1A1;HDAC1 GO:0007623| circadian rhythm AANAT;HDAC3 GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;GSR;HDAC1 GO:0055093| response to hyperoxia CAT;HDAC2;CYP1A1;HDAC1 GO:0035094| response to nicotine HDAC2;CHRNA7;CNR1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;HDAC1;PPARG GO:0006355| regulation of transcription, DNA-dependent HDAC2;HDAC8;HDAC3;HDAC6;PPARG;HDAC1 GO:0042493| response to drug CAT;HDAC2;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;HDAC1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0001975| response to amphetamine SOD1;CNR2;HDAC2;HDAC1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1;HDAC3 GO:0008285| negative regulation of cell proliferation CYP1B1;HDAC1;PPARG;OPRM1;PTGS2 GO:0070301| cellular response to hydrogen peroxide CYP1B1;HDAC2;HDAC6 GO:0009636| response to toxin CYP1A1;CYP1B1;HDAC6;CAT;GPX1 GO:0040029| regulation of gene expression, epigenetic GPX1;HDAC6 GO:0006351| transcription, DNA-dependent HDAC2;HDAC8;HDAC3;HDAC6;PPARG;HDAC1 GO:0045598| regulation of fat cell differentiation HDAC6;PPARG GO:0016032| viral reproduction HTR2A;HDAC1;VDAC1 GO:0071498| cellular response to fluid shear stress PTGS2;HDAC3 GO:0048149| behavioral response to ethanol OPRM1;HDAC2 GO:0043524| negative regulation of neuron apoptosis HDAC1;SOD1 GO:0010629| negative regulation of gene expression OPRD1;HDAC8;HDAC1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;HDAC3 17641:[DB14011 DB00848] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways GO:0007626| locomotory behavior CHRNA3;OPRM1;SOD1 GO:1905144| CHRNA3;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;CHRNA3;GLRA1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;CHRNA3;GLRB;TRPV1 GO:0095500| CHRNA3;CHRNA7 GO:0042391| regulation of membrane potential GLRB;CHRNA3;GLRA1;CACNA1G;CACNA1H GO:0007399| nervous system development CHRNA3;GLRB;SMPD1 GO:0008152| metabolic process ACAT1;ALPPL2;SMPD1 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;VDAC1;CHRNA3;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CHRNA3;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 17642:[DB14011 DB04947] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04947|Altropane SLC6A3 common genes common pathways GO:0042053| regulation of dopamine metabolic process SLC6A3;HTR1A GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;CYP1A1;PPARG;TRPA1;SLC6A3 GO:0007595| lactation SLC29A1;SLC6A3 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC6A3 GO:0045471| response to ethanol SLC6A3;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;SLC6A3;TRPV1;CACNA1I;TRPV4;VDAC1;CACNA1H;TRPV3;TRPV2 GO:0042220| response to cocaine CNR1;OPRM1;SMPD1;SLC6A3 GO:0051591| response to cAMP SLC6A3;AANAT GO:0007568| aging SLC6A3;CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1 GO:0035094| response to nicotine CNR1;CHRNA7;SLC6A3 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;SLC6A3;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0007626| locomotory behavior SLC6A3;OPRM1;SOD1 17643:[DB14011 DB01860] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 17644:[DB14011 DB04080] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04080|RU78191 SRC common genes common pathways GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;SRC;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;GPX1;SRC GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;SRC GO:0070542| response to fatty acid CAT;SRC;PTGS2 GO:0045453| bone resorption GPR55;SRC GO:0008283| cell proliferation HTR1A;SRC;GPX1;CYP1A1 GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0045087| innate immune response PPARG;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;SRC;CAT GO:0042493| response to drug SRC;CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG GO:0016236| macroautophagy SRC;VDAC1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0002376| immune system process SRC;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;SRC;CHRNA7 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010628| positive regulation of gene expression SRC;TRPV4 17645:[DB14011 DB02917] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways GO:0010629| negative regulation of gene expression HDAC8;OPRD1 GO:0006351| transcription, DNA-dependent HDAC8;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;HDAC8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;HDAC8 17646:[DB14011 DB02226] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0008283| cell proliferation GPX1;ACHE;HTR1A;CYP1A1 GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE 17647:[DB14011 DB09018] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09018|Bromopride DRD2 common genes common pathways GO:0048678| response to axon injury SOD1;DRD2 GO:0045776| negative regulation of blood pressure CNR1;DRD2 GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0048148| behavioral response to cocaine HTR2A;DRD2 GO:0001659| temperature homeostasis TRPV1;DRD2;HTR2A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0008542| visual learning DRD2;HMGCR GO:0001964| startle response GLRA1;DRD2;GLRB GO:0001975| response to amphetamine DRD2;SOD1;CNR2 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;DRD2;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:1900273| DRD2;CHRNA7 GO:0050482| arachidonic acid secretion PLA2G1B;DRD2 GO:0014854| response to inactivity DRD2;CAT GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1;DRD2 GO:0008285| negative regulation of cell proliferation CYP1B1;DRD2;PPARG;OPRM1;PTGS2 GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;DRD2;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0007628| adult walking behavior DRD2;GLRB;GLRA1 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0007626| locomotory behavior SOD1;OPRM1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;PPARG GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;DRD2;ABCG2 GO:0043278| response to morphine DRD2;OPRM1;CNR1 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0035094| response to nicotine CHRNA7;CNR1;DRD2 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;DRD2;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;DRD2;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;DRD2;TRPV4;TRPM8 GO:0042220| response to cocaine CNR1;OPRM1;SMPD1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;DRD2 GO:0014059| regulation of dopamine secretion DRD2;HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;DRD2 GO:0009416| response to light stimulus AANAT;DRD2 GO:0001666| response to hypoxia CHRNA7;CAT;DRD2;CYP1A1 17648:[DB14011 DB01096] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01096|Oxamniquine CYP2D6 common genes CYP2D6 common pathways GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0051100| negative regulation of binding CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;DAGLA;CYP2D6;ALOX15 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 17649:[DB14011 DB05990] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes CYP1A2 common pathways GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045087| innate immune response PPARG;NR1H4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;TRPV1;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;NR1H4;HMGCR;SOD1;GPX1;CAT GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0032259| methylation CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR1H4 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;CYP1A1;IDO1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1H4;PPARG GO:0050728| negative regulation of inflammatory response CNR2;NR1H4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0006631| fatty acid metabolic process BAAT;PTGS2;PTGS1;ALOX15 GO:0006355| regulation of transcription, DNA-dependent NR1H4;PPARG GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7;NR1H4 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;NR1H4 GO:0031100| organ regeneration PPARG;BAAT GO:0002376| immune system process NR1H4;IDO1 GO:0010468| regulation of gene expression CYP1A2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0007043| cell-cell junction assembly TRPV4;NR1H4 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;BAAT;NAAA;PTGS1;GPX1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0001889| liver development BAAT;ACAT1;CYP1A1 GO:0006351| transcription, DNA-dependent PPARG;NR1H4 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1H4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NR1H4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;CNR2;PTGS2;NR1H4;PTGS1;ALOX5 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;NR1H4;OPRD1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;NR1H4;CAT GO:0045333| cellular respiration CYP1A2 17650:[DB14011 DB06061] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06061|AZD-8330 MAP3K1 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K1;PTGS2 17651:[DB14011 DB05797] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05797|TNX-901 FCER1A common genes common pathways 17652:[DB14011 DB07402] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07402|Azapropazone ALB common genes common pathways GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0098869| PTGS2;GPX1;PTGS1;CAT;ALB;GSR GO:0001895| retina homeostasis SOD1;ALB 17653:[DB14011 DB04700] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways GO:0098869| GSR;PTGS2;PTGS1;GPX1;CAT;GSTK1 GO:0030855| epithelial cell differentiation GSTK1;VDAC1;PPARG GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;GSTK1;CAT GO:0006749| glutathione metabolic process GSTK1;GPX1;SOD1;GSR 17654:[DB14011 DB04593] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F7;GPX1 GO:0007623| circadian rhythm F7;AANAT GO:0001666| response to hypoxia CAT;CHRNA7;F7;CYP1A1 GO:0031100| organ regeneration F7;PPARG GO:0032355| response to estradiol stimulus F7;PTGS2;CYP1A2;CAT GO:0031667| response to nutrient levels SOD1;F7 GO:0043627| response to estrogen stimulus F7;PPARG GO:0014070| response to organic cyclic compound F7;TRPA1;CYP1A1;PPARG;ACAT1;AANAT;PTGS2;CYP1A2 GO:0009725| response to hormone stimulus ACAT1;F7 17655:[DB14011 DB08054] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08054|1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process SRC;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug CAT;SRC;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0002376| immune system process IDO1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0042542| response to hydrogen peroxide SRC;GPX1;CAT;SOD1;TRPA1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;SRC;PTGS2;SOD1;CNR1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;SRC;CHRNA7 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption GPR55;SRC GO:0008283| cell proliferation CYP1A1;SRC;GPX1;HTR1A 17656:[DB14011 DB03082] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03082|6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide PLAU common genes common pathways GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;PLAU;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;PLAU GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLAU 17657:[DB14011 DB02209] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;PNPO;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0009615| response to virus CYP1A1;ODC1 GO:0008284| positive regulation of cell proliferation CHRNA7;ODC1;HTR1A;HTR2A;PTGS2;HMGCR GO:0001822| kidney development ODC1;CAT 17658:[DB14011 DB05088] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05088|Tiomolibdate ion APP common genes common pathways GO:0007399| nervous system development GLRB;APP;SMPD1 GO:1990090| TRPV1;APP GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0043065| positive regulation of apoptotic process SMPD1;APP;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0001774| microglial cell activation TRPV1;APP GO:0008542| visual learning HMGCR;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;APP;CAT GO:1902004| CHRNA7;APP GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:0071320| cellular response to cAMP APP;AANAT GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;APP;CACNA1G;GLRA3;HTR2A;OPRD1;OPRM1 GO:0010629| negative regulation of gene expression APP;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1;PTGS2 GO:1900273| APP;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration APP;TRPV1;TRPV4;HTR2A;OPRM1 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7;APP GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;APP;OPRM1;PTGS2 GO:0061844| PLA2G1B;APP GO:0032930| positive regulation of superoxide anion generation APP;SOD1 GO:0008344| adult locomotory behavior OPRD1;APP GO:0010288| response to lead ion CAT;APP GO:0007155| cell adhesion APP;CYP1B1 GO:0045087| innate immune response APP;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;PPARG;TRPV1;TRPV4 GO:0007626| locomotory behavior APP;SOD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;APP;PPARG GO:0002576| platelet degranulation APP;SOD1 GO:1905906| CHRNA7;APP GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:0007611| learning or memory APP;CHRNA7;CNR1 GO:0008203| cholesterol metabolic process HMGCR;CAT;APP GO:0007612| learning PTGS2;VDAC1;APP GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0050808| synapse organization CHRNA7;APP GO:0019731| antibacterial humoral response PLA2G1B;APP GO:0050830| defense response to Gram-positive bacterium APP;PLA2G1B GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;APP GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;APP GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;APP GO:0010468| regulation of gene expression APP;CYP1A2 GO:0098815| CHRNA7;APP GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;APP;GPR18;PPARG GO:0051262| protein tetramerization APP;HMGCR;CAT GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0000187| activation of MAPK activity PLA2G1B;APP;CHRNA7;SOD1 GO:0006915| apoptotic process GPX1;VDAC1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;APP 17659:[DB14011 DB04351] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04351|Aconitate Ion ACO2 common genes common pathways GO:0001889| liver development CYP1A1;ACO2;ACAT1 GO:0008152| metabolic process SMPD1;ACO2;ACAT1 GO:0035900| response to isolation stress NAPEPLD;ACO2 17660:[DB14011 DB08590] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways GO:0045087| innate immune response IRAK4;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation IRAK4;PTGS2;HMGCR GO:0002446| neutrophil mediated immunity IRAK4;PLA2G1B GO:0002376| immune system process IDO1;IRAK4 GO:0051092| positive regulation of NF-kappaB transcription factor activity IRAK4;PLA2G1B;CAT GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;IRAK4;CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1 17661:[DB14011 DB05749] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05749|MPI-674 CYP19A1 common genes common pathways GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP19A1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0022900| electron transport chain GSR;IDO1;CYP19A1;CYP1A2 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP19A1;CYP1A1;CYP2C9;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0006694| steroid biosynthetic process HMGCR;CYP19A1;CYP17A1 17662:[DB14011 DB09363] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CAT;MAOB GO:0007268| synaptic transmission VDAC1;GLRB;SLC6A2;CACNA1G;GLRA1;OPRD1;OPRM1;GLRA3;HTR2A;SLC18A2 GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0001975| response to amphetamine CNR2;SLC18A2;SOD1 GO:0009791| post-embryonic development CYP1A2;SLC18A2 GO:0009636| response to toxin GPX1;CAT;SLC18A2;CYP1B1;MAOB;CYP1A1 GO:0010269| response to selenium ion GPX1;MAOB GO:0007626| locomotory behavior SLC18A2;SOD1;OPRM1 GO:0007269| neurotransmitter secretion NAAA;SLC18A2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;MAOB;CYP1A1 GO:0048265| response to pain TRPV1;TRPA1;SLC6A2 GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;MAOA;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1;CYP1A1;CYP2C9;CRYZ;MAOB;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;MAOB;ABCC1;SMPD1;SLC6A2 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;MAOB GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCG2;SLC6A2;ABCC1 GO:0055085| transmembrane transport TRPA1;CACNA1G;SLC6A2;ABCC1;ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;SLC18A2;CACNA1H;TRPV3;TRPV2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 17663:[DB14011 DB01858] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01858|[1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate CTSK common genes common pathways GO:0045453| bone resorption CTSK;GPR55 GO:1903146| VDAC1;CTSK 17664:[DB14011 DB01256] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01256|Retapamulin rplC;CYP3A4 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;PTGS1;GPX1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 17665:[DB14011 DB00944] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00944|Demecarium ACHE;BCHE common genes common pathways GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;BCHE;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0007517| muscle organ development ACHE;CACNA1H GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0007155| cell adhesion ACHE;CYP1B1 GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development ACHE;SMPD1;GLRB GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;BCHE;PPARG;CYP1B1 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 17666:[DB14011 DB04345] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways GO:0055114| oxidation-reduction process BLVRB;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT 17667:[DB14011 DB13192] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;PROC;GPX1 GO:0050728| negative regulation of inflammatory response PROC;CNR2 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0001889| liver development ACAT1;PROC;CYP1A1 17668:[DB14011 DB01564] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01564|Calusterone AR common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;AR GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation CYP1A1;AR;GPX1;HTR1A GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;AR;CHRNA7 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006351| transcription, DNA-dependent PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;AR;TRPV2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HMGCR;PTGS2;HTR2A;HTR1A 17669:[DB14011 DB01324] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01324|Polythiazide SLC12A3 common genes common pathways GO:1902476| GLRA3;SLC12A3;GLRA1;GLRB GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;SLC12A3 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;SLC12A3 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;SLC12A3;CACNA1H;TRPV3 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;TRPV2;SLC12A3 17670:[DB14011 DB03058] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways GO:0002376| immune system process CFD;IDO1 GO:0043312| neutrophil degranulation ALOX5;CFD;CAT GO:0045087| innate immune response PPARG;CFD GO:0002576| platelet degranulation CFD;SOD1 17671:[DB14011 DB05005] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05005|CCX282 CCR9 common genes common pathways GO:0002305| CD8-positive, gamma-delta intraepithelial T cell differentiation CCR9;GPR18 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;CCR9;TRPV4;TRPV1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;CCR9;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0006955| immune response OPRD1;CNR2;CCR9 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CCR9 17672:[DB14011 DB03759] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03759|FG-9041 GRIA2 common genes common pathways GO:0034220| ion transmembrane transport TRPA1;GLRA1;GLRB;TRPV1;GLRA3;CHRNA7;GRIA2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;CHRNA7;SLC29A1;GRIA2;GLRA3;OPRM1 GO:0006811| ion transport TRPV2;GRIA2;CHRNA7;TRPV3;CACNA1H;GLRA3;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0007165| signal transduction CHRNA7;GRIA2;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;GRIA2;GLRA3;HTR2A;OPRD1;OPRM1 17673:[DB14011 DB08008] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;DHODH;AANAT;ACAT1 GO:0043065| positive regulation of apoptotic process DHODH;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy DHODH;IDO1 GO:0031000| response to caffeine PPARG;DHODH GO:0042594| response to starvation ACAT1;DHODH;PPARG GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;DHODH;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;DHODH;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6 17674:[DB14011 DB08063] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08063|1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE RXRA;NR1H3 common genes common pathways GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;RXRA;PPARG;CYP1A1 GO:0007566| embryo implantation RXRA;SOD1;PTGS2 GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0010887| negative regulation of cholesterol storage PPARG;NR1H3 GO:0055088| lipid homeostasis PPARG;NR1H3 GO:0001890| placenta development PPARG;RXRA;SOD1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;NR1H3 GO:0010745| negative regulation of macrophage derived foam cell differentiation NR1H3;PPARG GO:0007507| heart development RXRA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0006351| transcription, DNA-dependent NR1H3;RXRA;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1H3;RXRA;PPARG GO:0051289| protein homotetramerization CRYZ;TRPA1;RXRA;TRPM8;TRPV1;CAT GO:0016032| viral reproduction VDAC1;RXRA;HTR2A GO:0042752| regulation of circadian rhythm NR1H3;PPARG GO:0043277| apoptotic cell clearance NR1H3;ALOX15 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;PLA2G1B;RXRA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;RXRA;TRPV1;TRPV4;NR1H3 GO:0008203| cholesterol metabolic process RXRA;CAT;HMGCR GO:0032526| response to retinoic acid RXRA;PPARG GO:0050728| negative regulation of inflammatory response CNR2;NR1H3 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR1H3 GO:0006355| regulation of transcription, DNA-dependent NR1H3;RXRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1H3;RXRA;PPARG 17675:[DB14011 DB01754] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01754|3,4-Dihydroxy-1-Methylquinolin-2(1h)-One PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;PIM1;SOD1;GPX1;CAT GO:0006915| apoptotic process VDAC1;GPX1;PIM1 GO:0008283| cell proliferation CYP1A1;HTR1A;PIM1;GPX1 17676:[DB14011 DB03686] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways GO:0043407| negative regulation of MAP kinase activity HMGCR;GSTP1;SMPD1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0043200| response to amino acid stimulus GLRB;GSTP1;GLRA3 GO:0098869| GSTP1;GSR;PTGS2;PTGS1;GPX1;CAT GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GSTP1;GPR18 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;GSTP1 GO:0043312| neutrophil degranulation GSTP1;ALOX5;CAT GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;GSTP1 GO:0034599| cellular response to oxidative stress GSR;GSTP1;CAT;GPX1;SOD1 GO:0000302| response to reactive oxygen species GSTP1;CAT;GPX1;SOD1 GO:0032930| positive regulation of superoxide anion generation SOD1;GSTP1 GO:0006749| glutathione metabolic process GSTP1;GSR;SOD1;GPX1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0009636| response to toxin CAT;GPX1;GSTP1;CYP1B1;CYP1A1 GO:0032869| cellular response to insulin stimulus PLA2G1B;GSTP1;PPARG GO:1904706| GSTP1;PPARG GO:0031667| response to nutrient levels GSTP1;SOD1 GO:0008152| metabolic process ACAT1;GSTP1;SMPD1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;GSTP1;CYP1B1 GO:0045471| response to ethanol CAT;CNR1;SOD1;OPRM1;HMGCR;GSTP1 17677:[DB14011 DB03309] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways GO:0043524| negative regulation of neuron apoptosis EN2;SOD1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;SULT2B1;CYP1A2;PTGS2;PTGS1;NAAA;GPX1;CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 GO:0008285| negative regulation of cell proliferation SULT2B1;PTGS2;OPRM1;CYP1B1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;EN2 GO:0008203| cholesterol metabolic process CAT;SULT2B1;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EN2;PPARG;PLA2G1B GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP3A7;CYP1A2;SULT2B1;HMGCR;CYP3A4 17678:[DB14011 DB08118] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08118|2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways GO:0032869| cellular response to insulin stimulus GCK;PPARG;PLA2G1B GO:0050796| regulation of insulin secretion CNR1;GCK GO:0008152| metabolic process SMPD1;GCK;ACAT1 GO:0042593| glucose homeostasis CNR1;GCK;TRPV4;PPARG GO:0070509| calcium ion import CACNA1H;GCK;CACNA1I;TRPV4;CACNA1G 17679:[DB14011 DB04003] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways GO:0051209| release of sequestered calcium ion into cytosol LCK;TRPV1;TRPA1;HTR2A GO:0051897| positive regulation of protein kinase B signaling cascade LCK;GPX1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;LCK;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0045087| innate immune response LCK;PPARG GO:0042127| regulation of cell proliferation PTGS2;PTGS1;LCK GO:0006919| activation of caspase activity LCK;PPARG GO:0016032| viral reproduction LCK;VDAC1;HTR2A GO:0030217| T cell differentiation LCK;GPR18 17680:[DB14011 DB04767] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways GO:0031667| response to nutrient levels SOD1;F7 GO:0009725| response to hormone stimulus ACAT1;F7 GO:0043627| response to estrogen stimulus PPARG;F7 GO:0014070| response to organic cyclic compound F7;PPARG;CYP1A1;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0007623| circadian rhythm F7;AANAT GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F7 GO:0031100| organ regeneration PPARG;F7 GO:0032355| response to estradiol stimulus F7;PTGS2;CYP1A2;CAT GO:0001666| response to hypoxia CAT;CHRNA7;F7;CYP1A1 17681:[DB14011 DB04579] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04579|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}- CTSB common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;CTSB GO:0046697| decidualization PTGS2;CTSB GO:0030855| epithelial cell differentiation PPARG;VDAC1;CTSB GO:0046718| entry of virus into host cell CTSB;HTR2A 17682:[DB14011 DB01784] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01784|4-Flourobenzenesulfonamide CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 17683:[DB14011 DB07195] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07195|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CYP1A1;HMGCR;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV4;TRPV1 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction HTR2A;GPR12;CNR1;ESR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0048511| rhythmic process PPARG;NCOA2;AANAT GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;NCOA2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0007623| circadian rhythm NCOA2;AANAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;NCOA2;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV1;TRPV4;PPARG;NCOA2 17684:[DB14011 DB08430] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08430|PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE LCTL common genes common pathways 17685:[DB14011 DB11127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes GPX1 common pathways GO:0060047| heart contraction SOD1;GPX1 GO:0060055| angiogenesis involved in wound healing GPX1 GO:0010332| response to gamma radiation GPX1 GO:0006641| triglyceride metabolic process GPX1;CAT GO:0061136| regulation of proteasomal protein catabolic process GPX1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;TXNRD1;CHRNA7 GO:0045454| cell redox homeostasis GSR;GPX1;TXNRD1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;TXNRD1;HMGCR;CNR1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1 GO:0006749| glutathione metabolic process GPX1;SOD1;GSR GO:0009609| response to symbiotic bacterium GPX1 GO:0001885| endothelial cell development GPX1 GO:0009650| UV protection CAT;GPX1 GO:1902042| GPX1 GO:0010269| response to selenium ion GPX1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT GO:0008283| cell proliferation HTR1A;GPX1;TXNRD1;CYP1A1 GO:0051450| myoblast proliferation GPX1 GO:0040029| regulation of gene expression, epigenetic GPX1 GO:0015949| nucleobase-containing small molecule interconversion GSR;TXNRD1 GO:1902905| GPX1 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;GPX1;CAT GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0043403| skeletal muscle tissue regeneration GPX1 GO:0033599| regulation of mammary gland epithelial cell proliferation GPX1 GO:0043534| blood vessel endothelial cell migration GPX1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0006195| purine nucleotide catabolic process GPX1 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1 GO:0098869| GSR;PTGS2;CAT;PTGS1;GPX1;TXNRD1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT GO:0007605| sensory perception of sound SOD1;GPX1 GO:0009611| response to wounding CYP1A1;GPX1 GO:0048741| skeletal muscle fiber development GPX1 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT GO:0006915| apoptotic process VDAC1;GPX1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0042311| vasodilation GPX1 GO:0009410| response to xenobiotic stimulus GPX1 GO:0043523| regulation of neuron apoptosis GPX1 GO:0014902| myotube differentiation GPX1 GO:0000302| response to reactive oxygen species SOD1;CAT;GPX1 GO:0034599| cellular response to oxidative stress GSR;SOD1;CAT;TXNRD1;GPX1 GO:0033194| response to hydroperoxide GPX1 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0002862| negative regulation of inflammatory response to antigenic stimulus GPX1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1 GO:0022900| electron transport chain CYP1A2;TXNRD1;GSR;IDO1 GO:0045444| fat cell differentiation GPX1 GO:0018158| protein oxidation GPX1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;ALOX5;PTGS1;GPX1;TXNRD1 GO:0051702| interaction with symbiont GPX1 GO:1902176| GPX1 17686:[DB14011 DB03429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03429|Cardiolipin SLC25A4 common genes common pathways GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;SLC25A4;TRPV2 GO:0055085| transmembrane transport TRPA1;SLC25A4;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;TRPV4;CACNA1I;TRPV3;CACNA1H;TRPV2 GO:0050796| regulation of insulin secretion SLC25A4;CNR1 GO:0016032| viral reproduction HTR2A;SLC25A4;VDAC1 17687:[DB14011 DB04417] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04417|P-Nitrophenol SULT1A1;AMY2B common genes common pathways GO:0009812| flavonoid metabolic process SULT1A1;CYP1A1 GO:0008210| estrogen metabolic process SULT1A1;CYP1B1 GO:0009308| amine metabolic process CYP1A1;SULT1A1 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1A1;CYP2C9;SULT1A1;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;SULT1A1;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;SULT1A1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0008152| metabolic process AMY2B;SMPD1;ACAT1 17688:[DB14011 DB09204] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes CYP2D6 common pathways GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0019369| arachidonic acid metabolic process FAAH;ALOX15;DAGLA;CYP2D6;CYP1B1 GO:0042493| response to drug ADRA1A;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;GPX1;ALOX5;PTGS1;CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1 GO:0002576| platelet degranulation SOD1;ALB;ORM1 GO:0008284| positive regulation of cell proliferation ADRA1D;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;ALB GO:0043312| neutrophil degranulation ORM1;ALOX5;CAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;ADRA1B;ADRA1D;ADRA1A GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0002024| diet induced thermogenesis ADRB2;TRPV1;ADRB1;TRPV4 GO:0007202| activation of phospholipase C activity HTR2A;GPR55;ADRA1A GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;ADRA1A;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0006915| apoptotic process ADRA1A;VDAC1;GPX1 GO:0042593| glucose homeostasis CNR1;ADRA1B;PPARG;TRPV4 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;ORM1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;ALB;GSR GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway ADRA1B;ADRB2;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;ADRA1A;ADRB1;GPR18;PPARG;ADRA1D GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1 GO:0007568| aging CAT;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;ADRA1A;CYP1A1 GO:0006954| inflammatory response ORM1;TRPV1;IDO1;ALOX15;CNR2;PTGS2;PTGS1;ALOX5 GO:0001659| temperature homeostasis HTR2A;GPX1;TRPV1;ADRB1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRA1D;ADRB2;CNR1;ADRA1B GO:0035556| intracellular signal transduction PLA2G1B;ADRA1A;ADRA1B GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0009409| response to cold ADRB2;TRPA1;PPARG;TRPM8;ADRB1 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;GPX1;NAAA;PTGS1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0050873| brown fat cell differentiation ADRB1;ADRB2;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ADRB2 GO:0051100| negative regulation of binding CYP2D6 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D GO:0008285| negative regulation of cell proliferation CYP1B1;ADRA1A;PPARG;OPRM1;PTGS2 GO:0008283| cell proliferation CYP1A1;ADRA1D;HTR1A;ADRA1B;GPX1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0001895| retina homeostasis ALB;SOD1 GO:0045453| bone resorption ADRB2;GPR55 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;HTR2A;ADRA1A;ADRA1D GO:0007165| signal transduction ADRA1B;CHRNA7;GPR55;HTR1A;ADRB2;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;ADRA1A;CACNA1I;ADRB1;PLA2G1B;PPARG;GPR18;ADRA1D;SMPD1 GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;OPRM1;HTR2A;TRPV4;ADRA1A;TRPV1;ADRA1D 17689:[DB14011 DB08388] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08388|5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE MMP13 common genes common pathways GO:0030282| bone mineralization ALOX15;MMP13;PTGS2 17690:[DB14011 DB08826] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08826|Deferiprone UGT1A6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A6;CYP1A2;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0008152| metabolic process ACAT1;UGT1A6;SMPD1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;UGT1A6;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 17691:[DB14011 DB08588] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0001666| response to hypoxia CHRNA7;CAT;DPP4;CYP1A1 GO:0008284| positive regulation of cell proliferation DPP4;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 17692:[DB14011 DB01205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0009636| response to toxin CYP1A1;CYP1B1;GABRB1;GPX1;CAT GO:0006811| ion transport GLRA3;GABRA1;GABRA6;GABRA4;GABRG2;GABRB1;TRPV3;GABRQ;CACNA1H;GABRE;CHRNA7;GABRG3;GABRB3;TRPV2;GABRP;GLRA1;TRPA1;GABRD;GABRB2;GABRA5;GABRA3;GABRG1;CACNA1G;TRPM8;GABRA2;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1 GO:0009791| post-embryonic development CYP1A2;GABRG2 GO:0001662| behavioral fear response GABRA5;VDAC1;HTR1A GO:0006821| chloride transport GABRA2;GLRB;GABRB2;GABRD;GLRA1;GABRP;GABRG1;GABRA3;GABRA5;GABRB3;GABRG3;GABRA4;GABRA6;GABRA1;GLRA3;GABRE;GABRQ;GABRB1;GABRG2 GO:0007420| brain development ACAT1;GABRA5 GO:0007165| signal transduction GABRQ;OPRD1;GABRB1;CNR2;GABRE;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GABRA6;GPR55;CHRNA7;GABRB3;GABRA5;SMPD1;GPR18;GABRP;GABRD;PPARG;CACNA1I;PLA2G1B GO:0043524| negative regulation of neuron apoptosis GABRA5;GABRB2;GABRB3;SOD1 GO:0007268| synaptic transmission GABRB2;GABRD;GLRA1;CACNA1G;GABRG1;GABRA5;VDAC1;GLRB;GLRA3;HTR2A;OPRM1;OPRD1;GABRG2 GO:1902476| GABRA2;GLRB;GABRP;GLRA1;GABRB2;GABRD;GABRA5;GABRA3;GABRG1;GABRG3;GABRB3;GABRA1;GLRA3;GABRA4;GABRA6;GABRB1;GABRG2;GABRQ;GABRE GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GABRA1 GO:0034220| ion transmembrane transport GABRE;GABRQ;GABRG2;GABRB1;GABRA4;GABRA6;GABRA1;GLRA3;GABRB3;GABRG3;CHRNA7;GABRG1;GABRA3;GABRA5;GABRB2;GABRD;GLRA1;TRPA1;GABRP;GLRB;TRPV1;GABRA2 GO:0060080| regulation of inhibitory postsynaptic membrane potential GABRB3;GLRA1 GO:0006810| transport GABRB3;TRPV2;GABRA1;GABRA6;GABRA4;GABRG2;GABRB1;ABCG2;TRPV1;CACNA1I;GABRD;GABRB2;GABRA5;GABRA3;ABCC1 GO:0007605| sensory perception of sound GABRB3;GPX1;SOD1;GABRB2;GABRA5 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT;GABRG3 GO:0043523| regulation of neuron apoptosis GABRB2;GABRA5;GABRB3;GPX1 17693:[DB14011 DB08643] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08643|2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER MMP3 common genes common pathways 17694:[DB14011 DB08504] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;DPP4 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DPP4 17695:[DB14011 DB03696] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03696|Lanosterol LSS common genes common pathways GO:0006695| cholesterol biosynthetic process LSS;HMGCR GO:0006694| steroid biosynthetic process HMGCR;LSS;CYP17A1 GO:0045540| regulation of cholesterol biosynthetic process LSS;HMGCR GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;LSS;NAAA;PTGS1;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD 17696:[DB14011 DB06013] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06013|Aldoxorubicin TOP2A common genes common pathways GO:0048511| rhythmic process AANAT;PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;TOP2A;PPARG;TRPV1;CYP1B1;IDO1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG 17697:[DB14011 DB05968] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05968|PR-104 TNF common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0006955| immune response OPRD1;CNR2;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;TNF;CAT GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;IDO1;ALOX15;TNF GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation TNF;PTGS2;CNR1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;TNF;PPARG;CYP1B1;TRPV1;IDO1 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0006919| activation of caspase activity PPARG;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0050796| regulation of insulin secretion CNR1;TNF GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2;OPRD1 GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;TNF GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0042127| regulation of cell proliferation TNF;PTGS2;PTGS1 GO:0046330| positive regulation of JNK cascade TRPV4;TNF GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TNF GO:0009615| response to virus TNF;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;TNF GO:0000187| activation of MAPK activity TNF;PLA2G1B;SOD1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;TNF;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0010628| positive regulation of gene expression TNF;TRPV4 GO:0010033| response to organic substance TNF;TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TNF;TRPV1 17698:[DB14011 DB01919] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01919|Pentanal PRKACA common genes common pathways GO:0071333| cellular response to glucose stimulus SLC29A1;PRKACA GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2;PRKACA GO:0002027| regulation of heart rate CACNA1G;PRKACA GO:0061136| regulation of proteasomal protein catabolic process PRKACA;GPX1 17699:[DB14011 DB02045] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02045|Amylamine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 17700:[DB14011 DB14004] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0050729| positive regulation of inflammatory response IL12B;TRPV4;IL23A GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CYP4A11;CNR1 GO:0048662| negative regulation of smooth muscle cell proliferation IL12B;PPARG GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP4A11;CYP1A2 GO:0008283| cell proliferation IL12B;CYP1A1;GPX1;HTR1A GO:0007166| cell surface receptor linked signaling pathway IL12B;TRPV1;TRPA1 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1;TRPA1;IL12B;TRPV1 GO:0032693| negative regulation of interleukin-10 production IL23A;IL12B;IDO1 GO:0006954| inflammatory response CNR2;PTGS2;IL23A;PTGS1;ALOX5;IDO1;ALOX15;TRPV1 GO:0006955| immune response IL23A;CNR2;OPRD1 GO:0032735| positive regulation of interleukin-12 production IL23A;IDO1;IL12B GO:0002376| immune system process IL23A;IDO1 GO:0010033| response to organic substance IL12B;CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL23A;PPARG;PLA2G1B GO:0035722| interleukin-12-mediated signaling pathway SOD1;IL23A;IL12B GO:0019373| epoxygenase P450 pathway CYP4A11;CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0045087| innate immune response IL23A;PPARG GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5;CYP4A11 GO:0006631| fatty acid metabolic process PTGS2;CYP4A11;PTGS1;ALOX15 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP4A11;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;DAGLA;CYP2D6;FAAH;CYP4A11 GO:0002862| negative regulation of inflammatory response to antigenic stimulus IL12B;GPX1 17701:[DB14011 DB09148] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0006691| leukotriene metabolic process ALOX5;ABCC1;CYP4F2;ALOX15 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0055114| oxidation-reduction process CYP3A4;CYP2J2;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1;CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP4F2;CYP1B1 GO:0050808| synapse organization APP;CHRNA7 GO:0019731| antibacterial humoral response PLA2G1B;APP GO:0019369| arachidonic acid metabolic process CYP4F2;CYP1B1;ALOX15;DAGLA;CYP2D6;FAAH GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0007612| learning APP;VDAC1;PTGS2 GO:0008203| cholesterol metabolic process APP;HMGCR;CAT GO:0007611| learning or memory APP;CHRNA7;CNR1 GO:1905906| APP;CHRNA7 GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;PPARG;PLA2G1B GO:0007626| locomotory behavior APP;OPRM1;SOD1 GO:0002576| platelet degranulation SOD1;APP GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP4F2;CYP2C19;CYP1A2;CYP2J2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;PPARG;TRPV4;TRPV1 GO:0007155| cell adhesion APP;CYP1B1 GO:0045087| innate immune response PPARG;APP GO:0010288| response to lead ion CAT;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0006915| apoptotic process VDAC1;APP;GPX1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;APP;PLA2G1B GO:0010628| positive regulation of gene expression TRPV4;APP GO:2000463| positive regulation of excitatory postsynaptic membrane potential APP;CHRNA7 GO:0051262| protein tetramerization CAT;HMGCR;APP GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;PPARG;APP GO:0098815| APP;CHRNA7 GO:0010468| regulation of gene expression APP;CYP1A2 GO:0051260| protein homooligomerization ACAT1;GLRA3;APP;GLRA1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;APP GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;APP GO:0017144| drug metabolic process CYP4F2;CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0071320| cellular response to cAMP APP;AANAT GO:0010629| negative regulation of gene expression OPRD1;APP GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;GLRA1;APP;CACNA1G;GLRB;VDAC1 GO:0001934| positive regulation of protein phosphorylation APP;CHRNA7 GO:1902004| APP;CHRNA7 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;APP;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;APP GO:0008542| visual learning APP;HMGCR GO:0001774| microglial cell activation TRPV1;APP GO:0008016| regulation of heart contraction CYP2J2;CACNA1H GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0043065| positive regulation of apoptotic process SMPD1;APP;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2J2;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0007399| nervous system development APP;SMPD1;GLRB GO:1990090| TRPV1;APP GO:0008344| adult locomotory behavior OPRD1;APP GO:0032930| positive regulation of superoxide anion generation SOD1;APP GO:0061844| APP;PLA2G1B GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;CYP4F2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;APP;PPARG;CYP1B1 GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0007204| elevation of cytosolic calcium ion concentration APP;TRPV1;TRPV4;OPRM1;HTR2A GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2;APP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRD1;OPRM1 GO:1900273| APP;CHRNA7 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP4F2;CYP2C9;CYP1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP 17702:[DB14011 DB02401] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02401|4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid LDHB common genes common pathways GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;LDHB;CYP1B1;CYP2C9;CYP1A1;CRYZ 17703:[DB14011 DB03167] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03167|Pentabromophenol TTR common genes common pathways GO:0006810| transport ABCC1;CACNA1I;TRPV1;ABCG2;TRPV2;TTR GO:0043312| neutrophil degranulation ALOX5;CAT;TTR GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0042572| retinol metabolic process CYP1B1;TTR 17704:[DB14011 DB08782] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08782|4-(2-AMINOETHYL)BENZENESULFONAMIDE CA2 common genes common pathways GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CA2;TRPA1;CYP1A1;PPARG GO:0001822| kidney development CA2;CAT 17705:[DB14011 DB05786] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05786|Irofulven FUBP1 common genes common pathways GO:0006351| transcription, DNA-dependent FUBP1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;FUBP1 GO:0010628| positive regulation of gene expression TRPV4;FUBP1 17706:[DB14011 DB00407] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0007584| response to nutrient PPARG;CNR1;SERPINC1;HMGCR GO:0007595| lactation SERPINC1;SLC29A1 17707:[DB14011 DB02279] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02279|Benzoylformic Acid HAO1 common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;HAO1;CYP1A2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0006979| response to oxidative stress PTGS2;HAO1;SOD1;PTGS1;GPX1;CAT 17708:[DB14011 DB08338] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08338|19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one CSNK2A1 common genes common pathways GO:0007165| signal transduction CHRNA7;OPRD1;CSNK2A1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;CSNK2A1 GO:0048511| rhythmic process PPARG;AANAT;CSNK2A1 GO:0006915| apoptotic process VDAC1;CSNK2A1;GPX1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;CSNK2A1;HMGCR;CHRNA7 GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CSNK2A1 17709:[DB14011 DB07897] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07897|1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE F2 common genes common pathways GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;F2;GPR18;PPARG GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 17710:[DB14011 DB00966] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes CYP2C19;ABCG2;PPARG common pathways GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCB11;CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;ABCC2;CACNA1G;ABCC1;TRPA1 GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0048511| rhythmic process PPARG;AANAT GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;AGTR1;GPR55 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0006810| transport ABCC2;ABCG2;CACNA1I;ABCB1;TRPV1;ABCC1;TRPV2;ABCB11 GO:0015909| long-chain fatty acid transport PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;AGTR1;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0017144| drug metabolic process UGT1A3;CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0033993| response to lipid PPARG GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;ABCC2 GO:0043388| positive regulation of DNA binding PPARG GO:0030224| monocyte differentiation PPARG GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCC2;ABCG2;ABCB1;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0099133| ABCC1;ABCC2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0015886| heme transport ABCG2 GO:0060326| cell chemotaxis AGTR1;ABCC1 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0033344| cholesterol efflux ABCG2 GO:0032526| response to retinoic acid PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;AGTR1 GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;CYP1A1;ABCC2;IDO1 GO:0042127| regulation of cell proliferation PTGS2;AGTR1;PTGS1 GO:0030308| negative regulation of cell growth PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0001822| kidney development CAT;AGTR1 GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCG2;ABCB1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0006919| activation of caspase activity PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;PPARG GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;HTR2A;OPRM1;TRPV1;TRPV4 GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:1905461| PPARG GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;CNR1;HMGCR GO:0050729| positive regulation of inflammatory response TRPV4;AGTR1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;AGTR1;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0007565| female pregnancy IDO1;ABCC2 GO:0046415| urate metabolic process ABCG2 GO:0061614| PPARG GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:1904706| PPARG GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 GO:0009408| response to heat TRPV1;ABCC2;TRPV3;SOD1;TRPV2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0048469| cell maturation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;ABCB11;CACNA1H GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;NAAA;GPX1;PTGS1 GO:0051974| negative regulation of telomerase activity PPARG GO:0050727| regulation of inflammatory response AGTR1;PTGS2 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0008152| metabolic process SMPD1;ACAT1;UGT1A3 17711:[DB14011 DB04172] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04172|[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine PLAU common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;PLAU GO:0001666| response to hypoxia PLAU;CYP1A1;CHRNA7;CAT GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0043312| neutrophil degranulation PLAU;CAT;ALOX5 17712:[DB14011 DB06907] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;TTR 17713:[DB14011 DB04217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04217|L-2-amino-3-butynoic acid CTH;sufS common genes common pathways GO:0043066| negative regulation of apoptotic process GPX1;CAT;CTH;HMGCR;PTGS2;SOD1 GO:0051289| protein homotetramerization CAT;CTH;TRPM8;TRPV1;TRPA1;CRYZ GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;CTH;PLA2G1B 17714:[DB14011 DB05014] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0010976| positive regulation of neuron projection development RET;FGFR1;CNR1 GO:0016032| viral reproduction KDR;VDAC1;HTR2A GO:0010629| negative regulation of gene expression KDR;FGFR1;OPRD1 GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0042542| response to hydrogen peroxide TRPA1;PDGFRB;GPX1;CAT;SOD1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PDGFRB GO:0035556| intracellular signal transduction PDGFRB;PLA2G1B GO:0007399| nervous system development RET;SMPD1;GLRB GO:0001525| angiogenesis KDR;CYP1B1;FGFR1;PTGS2 GO:0048469| cell maturation FGFR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;FGFR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;PDGFRB GO:0090280| positive regulation of calcium ion import TRPV2;TRPV3;PDGFRB GO:0043627| response to estrogen stimulus PDGFRB;PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;PDGFRB;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;PDGFRB;CYP1A1 GO:0006919| activation of caspase activity RET;PPARG GO:0007420| brain development ACAT1;FGFR1 GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;RET;GPR18;PDGFRB;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0065009| regulation of molecular function RET;TRPV1 GO:0071345| cellular response to cytokine stimulus FLT3;TRPV1 GO:0010243| response to organic nitrogen TRPV1;PTGS2;FLT3 GO:0055093| response to hyperoxia PDGFRB;CYP1A1;CAT GO:0048661| positive regulation of smooth muscle cell proliferation PDGFRB;HMGCR;PTGS2 GO:0061298| retina vasculature development in camera-type eye PDGFRB;CYP1B1 GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRB;FGFR3;GPX1;FGFR1 GO:0060326| cell chemotaxis ABCC1;PDGFRB GO:0048265| response to pain TRPV1;TRPA1;RET GO:0006355| regulation of transcription, DNA-dependent FGFR1;PPARG GO:0042493| response to drug CAT;RET;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0045893| positive regulation of transcription, DNA-dependent RET;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;FGFR1;HTR2A;FLT3;KDR;FGFR3;PDGFRB GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;KDR;PDGFRB GO:0071300| cellular response to retinoic acid PPARG;RET GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;PPARG;TRPV4;TRPV1 GO:0007155| cell adhesion CYP1B1;RET GO:0042127| regulation of cell proliferation PTGS1;FGFR1;PTGS2 GO:0042060| wound healing PDGFRB;ALOX15;OPRM1 GO:0032526| response to retinoic acid PDGFRB;PPARG GO:0030324| lung development CYP1A2;FGFR1 GO:0001657| ureteric bud development RET;CAT;FGFR1 GO:0010628| positive regulation of gene expression RET;TRPV4 GO:0043406| positive regulation of MAP kinase activity PDGFRB;FLT3;HTR2A;FGFR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;KDR;ALOX15;FGFR3;PDGFRB GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7 GO:0006915| apoptotic process GPX1;VDAC1;FGFR3 GO:0031100| organ regeneration FLT3;PPARG GO:0033993| response to lipid PPARG;PDGFRB GO:0007605| sensory perception of sound FGFR1;SOD1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway PDGFRB;PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;PDGFRB GO:0010468| regulation of gene expression FGFR1;CYP1A2 GO:0035025| positive regulation of Rho protein signal transduction GPR55;GPR18;PDGFRB GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FGFR1;FLT3;CAT;PDGFRB;KDR GO:0030282| bone mineralization ALOX15;FGFR3;PTGS2 GO:0048514| blood vessel morphogenesis CYP1B1;FGFR1 GO:0007568| aging PDGFRB;CYP1A1;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT 17715:[DB14011 DB07713] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07713|(1S)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid MMP8 common genes common pathways GO:0043312| neutrophil degranulation CAT;MMP8;ALOX5 17716:[DB14011 DB11590] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes GSR;GPX1 common pathways GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0045444| fat cell differentiation GPX1 GO:0018158| protein oxidation GPX1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;SOD2;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0051702| interaction with symbiont GPX1 GO:1902176| SOD2;GPX1 GO:0033194| response to hydroperoxide GPX1 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0002862| negative regulation of inflammatory response to antigenic stimulus GPX1 GO:0006801| superoxide metabolic process SOD1;SOD2 GO:0035094| response to nicotine CNR1;SLC7A11;CHRNA7 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1 GO:0009410| response to xenobiotic stimulus GPX1 GO:0043523| regulation of neuron apoptosis GPX1 GO:0014902| myotube differentiation GPX1 GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;FXYD2 GO:0034599| cellular response to oxidative stress SOD2;GSR;SOD1;GPX1;CAT GO:0035722| interleukin-12-mediated signaling pathway SOD1;SOD2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;ALB GO:0042311| vasodilation GPX1 GO:0032259| methylation CYP1A2;MTR GO:0002576| platelet degranulation ALB;SOD1 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;TRPV1;GLRB;TRPA1;GLRA1;FXYD2 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT GO:0006915| apoptotic process VDAC1;ITPR1;GPX1 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;ITPR1;TRPV1;VDAC1;TRPV4;CACNA1I;TRPV3;CACNA1H;TRPV2 GO:0001666| response to hypoxia ITPR1;CYP1A1;CAT;CHRNA7 GO:0048741| skeletal muscle fiber development GPX1 GO:0009235| cobalamin metabolic process ABCC1;MTR GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;ITPR1;TRPA1 GO:0009611| response to wounding CYP1A1;GPX1 GO:0006810| transport FXYD2;ABCC1;ABCG2;TRPV1;CACNA1I;TRPV2 GO:0098869| CAT;GPX1;PTGS1;PTGS2;GSR;ALB GO:0006979| response to oxidative stress SOD1;PTGS2;SLC7A11;CAT;GPX1;PTGS1 GO:0007605| sensory perception of sound GPX1;SOD1 GO:0043524| negative regulation of neuron apoptosis SOD1;SOD2 GO:0043534| blood vessel endothelial cell migration GPX1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0006195| purine nucleotide catabolic process GPX1 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;GPX1 GO:0006816| calcium ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;TRPV1;TRPV4;CACNA1I;TRPM8;ITPR1;CACNA1G;TRPA1 GO:0033599| regulation of mammary gland epithelial cell proliferation GPX1 GO:0051289| protein homotetramerization TRPM8;TRPV1;SOD2;CRYZ;TRPA1;CAT GO:0019430| removal of superoxide radicals SOD1;SOD2 GO:0000303| response to superoxide SOD1;SOD2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;SOD2 GO:0048678| response to axon injury MTR;SOD1 GO:0043403| skeletal muscle tissue regeneration GPX1 GO:1902905| GPX1 GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;TRPA1 GO:0001659| temperature homeostasis TRPV1;HTR2A;GPX1 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6 GO:0007399| nervous system development GLRB;SMPD1;MTR GO:0010269| response to selenium ion GPX1 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;SLC7A11 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0051450| myoblast proliferation GPX1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;FXYD2;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8;ITPR1 GO:0001895| retina homeostasis SOD1;ALB GO:0040029| regulation of gene expression, epigenetic GPX1 GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0006749| glutathione metabolic process SOD1;GPX1;GSR GO:0009609| response to symbiotic bacterium GPX1 GO:0009791| post-embryonic development CYP1A2;ITPR1 GO:0008217| regulation of blood pressure PPARG;SOD2;PTGS2;SOD1;PTGS1 GO:0001885| endothelial cell development GPX1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;SOD2;CYP1B1 GO:0009650| UV protection GPX1;CAT GO:1902042| GPX1 GO:0045454| cell redox homeostasis GPX1;GSR GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1 GO:0050796| regulation of insulin secretion ITPR1;CNR1 GO:0070588| calcium ion transmembrane transport TRPV3;CACNA1H;OPRM1;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8;ITPR1 GO:0060047| heart contraction SOD1;GPX1 GO:0060055| angiogenesis involved in wound healing GPX1 GO:0065009| regulation of molecular function ITPR1;TRPV1 GO:0010332| response to gamma radiation GPX1 GO:0061136| regulation of proteasomal protein catabolic process GPX1 GO:0006641| triglyceride metabolic process CAT;GPX1 GO:0007420| brain development SLC7A11;ACAT1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;ITPR1;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7 17717:[DB14011 DB08607] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08607|(5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE CYP2C8;FABP4 common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP2C8;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;GPX1;PTGS1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2C8;CYP1B1 GO:0002933| CYP1A1;CYP3A5;CYP2C8;CYP3A7;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent FABP4;PPARG GO:0071356| cellular response to tumor necrosis factor FABP4;TRPV1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C8;CYP2C19 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C8;CYP2C19 GO:0050872| white fat cell differentiation FABP4;PPARG GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0050729| positive regulation of inflammatory response FABP4;TRPV4 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2C8 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6;CYP2C8 17718:[DB14011 DB02153] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02153|3-Sulfinoalanine PAPOLA;aroH;GSR;PRDX2;def;FABP4 common genes GSR common pathways GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0019430| removal of superoxide radicals SOD1;PRDX2 GO:0050872| white fat cell differentiation FABP4;PPARG GO:0045454| cell redox homeostasis GPX1;PRDX2;GSR GO:0050729| positive regulation of inflammatory response TRPV4;FABP4 GO:0006749| glutathione metabolic process GSR;GPX1;SOD1 GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;PRDX2;SOD1 GO:0034599| cellular response to oxidative stress GSR;GPX1;CAT;PRDX2;SOD1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PRDX2;CYP1A2;PTGS2;CYP3A7;CAT;GPX1;ALOX5;PTGS1 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PRDX2;PTGS2;SOD1 GO:0071356| cellular response to tumor necrosis factor TRPV1;FABP4 GO:0045892| negative regulation of transcription, DNA-dependent FABP4;PPARG GO:0042744| hydrogen peroxide catabolic process PRDX2;GPX1;CAT 17719:[DB14011 DB06481] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06481|Manitimus DHODH common genes common pathways GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy IDO1;DHODH GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;DHODH;PTGS2;SOD1;CNR1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;DHODH;ACAT1;AANAT GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;DHODH;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0055114| oxidation-reduction process DHODH;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0031000| response to caffeine DHODH;PPARG 17720:[DB14011 DB07015] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 17721:[DB14011 DB00167] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0001649| osteoblast differentiation IARS;CAT GO:0008283| cell proliferation GPX1;BCAT1;HTR1A;CYP1A1 GO:0008152| metabolic process ACADSB;BCAT1;ACAT1;SMPD1;BCAT2 GO:0006629| lipid metabolic process ACADSB;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0006550| isoleucine catabolic process BCAT2;ACAT1 GO:0055085| transmembrane transport TRPV3;SLC16A10;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2 GO:0009083| branched chain family amino acid catabolic process BCAT2;ACAT1;ACADSB;BCAT1 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1;ACADSB GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ACADSB;CAT;PTGS1;ALOX5;GPX1 17722:[DB14011 DB02459] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways GO:0002376| immune system process IDO1;CFB GO:0045087| innate immune response CFB;PPARG 17723:[DB14011 DB03845] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03845|P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate DTYMK common genes common pathways GO:0046686| response to cadmium ion CAT;DTYMK GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;DTYMK;TRPV1 GO:0045445| myoblast differentiation DTYMK;HMGCR GO:0015949| nucleobase-containing small molecule interconversion GSR;DTYMK GO:0008283| cell proliferation GPX1;HTR1A;DTYMK;CYP1A1 GO:0043627| response to estrogen stimulus PPARG;DTYMK 17724:[DB14011 DB02638] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways GO:0031394| positive regulation of prostaglandin biosynthetic process AVPR1A;PTGS2 GO:0045777| positive regulation of blood pressure AVPR2;CNR1;AVPR1A GO:0007204| elevation of cytosolic calcium ion concentration AVPR1A;HTR2A;OPRM1;AVPR1B;TRPV4;TRPV1 GO:0007165| signal transduction CACNA1I;PLA2G1B;AVPR2;PPARG;GPR18;AVPR1B;SMPD1;CHRNA7;AVPR1A;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0051412| response to corticosterone stimulus AVPR1A;AANAT GO:0032870| cellular response to hormone stimulus AVPR2;AVPR1B;CACNA1H;AVPR1A GO:0045907| positive regulation of vasoconstriction AVPR2;AVPR1B;PTGS2;HTR2A;AVPR1A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;AVPR2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;AVPR1A;SOD1;PTGS2;CYP1A2 GO:0010628| positive regulation of gene expression TRPV4;AVPR2 GO:0007202| activation of phospholipase C activity HTR2A;GPR55;AVPR1A;AVPR1B GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;AVPR1B;AVPR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;AVPR1A;OPRD1;OPRM1;CNR2 GO:0051970| negative regulation of transmission of nerve impulse GLRA1;AVPR1A GO:0014902| myotube differentiation GPX1;AVPR1A GO:0034097| response to cytokine stimulus PTGS2;AANAT;AVPR2 GO:0008284| positive regulation of cell proliferation HTR1A;AVPR1A;HTR2A;PTGS2;HMGCR;CHRNA7;AVPR2 17725:[DB14011 DB05159] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05159|CCX915 CCR2 common genes common pathways GO:0016525| negative regulation of angiogenesis PPARG;CCR2 GO:0009611| response to wounding CYP1A1;CCR2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway CCR2;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0006874| cellular calcium ion homeostasis CCR2;CHRNA7;HTR2A;GPR12;TRPV4;TRPM8 GO:0019233| sensory perception of pain CCR2;CNR1;HTR2A;OPRD1;OPRM1;PTGS2;CNR2;TRPV1;TRPA1 GO:0007194| negative regulation of adenylate cyclase activity CCR2;OPRM1 GO:0006954| inflammatory response PTGS1;ALOX5;CCR2;CNR2;PTGS2;TRPV1;IDO1;ALOX15 GO:0006955| immune response CCR2;CNR2;OPRD1 GO:0016032| viral reproduction VDAC1;CCR2;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration CCR2;HTR2A;OPRM1;TRPV1;TRPV4 GO:0050729| positive regulation of inflammatory response CCR2;TRPV4 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CCR2;CHRNA7 17726:[DB14011 DB06069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06069|XMT-1001 TOP1 common genes common pathways GO:0048511| rhythmic process TOP1;AANAT;PPARG GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;TOP1;SOD1;HTR2A;CAT GO:0007623| circadian rhythm TOP1;AANAT GO:0016032| viral reproduction VDAC1;HTR2A;TOP1 17727:[DB14011 DB02074] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02074|Butenoic Acid FABP1 common genes common pathways GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;FABP1;CNR1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;FABP1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;FABP1;GPX1 GO:0015909| long-chain fatty acid transport FABP1;PPARG GO:0071456| cellular response to hypoxia OPRD1;PTGS2;FABP1;SLC29A1 GO:0098869| GSR;CAT;PTGS1;GPX1;FABP1;PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;FABP1;PTGS2;SOD1;GPX1;CAT 17728:[DB14011 DB03572] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03572|FR230513 ADA common genes common pathways GO:0001666| response to hypoxia ADA;CHRNA7;CAT;CYP1A1 GO:0007568| aging CYP1A1;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;ADA GO:0043278| response to morphine CNR1;OPRM1;ADA GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;ADA;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2 GO:0007155| cell adhesion CYP1B1;ADA GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;ADA;GPX1;CAT GO:0030324| lung development ADA;CYP1A2 GO:0033197| response to vitamin E CAT;ADA GO:0001890| placenta development PPARG;SOD1;ADA GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;ADA;GPX1;CAT;SOD1 GO:0001889| liver development CYP1A1;ACAT1;ADA 17729:[DB14011 DB05712] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05712|AZD-9684 CPB2 common genes common pathways GO:0071333| cellular response to glucose stimulus SLC29A1;CPB2 GO:0042493| response to drug CPB2;CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 GO:0009408| response to heat TRPV1;TRPV2;CPB2;TRPV3;SOD1 17730:[DB14011 DB00467] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes CYP1A2 common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0048511| rhythmic process PPARG;TOP2A;AANAT GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;CYP1A1;PPARG GO:0010468| regulation of gene expression CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0043065| positive regulation of apoptotic process TOP2A;PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 17731:[DB14011 DB07013] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07013|TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE MMP13 common genes common pathways GO:0030282| bone mineralization ALOX15;MMP13;PTGS2 17732:[DB14011 DB08837] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CHRNA9 GO:0007405| neuroblast proliferation DAGLA;KCNA1 GO:0019228| regulation of action potential in neuron CACNA1I;KCNA1;CACNA1G;CACNA1H GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;CHRNA9;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;TRPV3 GO:0001964| startle response GLRB;KCNA1;GLRA1 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GLRB;VDAC1;KCNA1;GLRA1;CACNA1G GO:0050966| detection of mechanical stimulus involved in sensory perception of pain KCNA1;TRPA1;HTR2A GO:0070588| calcium ion transmembrane transport CHRNA9;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0034765| regulation of ion transmembrane transport CACNA1H;CACNA1G;CACNA1I;KCNA1 GO:0006641| triglyceride metabolic process GPX1;CAT;SLC22A4 GO:0007420| brain development KCNA1;ACAT1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA9 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA9;TRPV1;TRPV4;HTR2A;OPRM1 GO:0098656| VDAC1;SLC22A8 GO:0006812| cation transport SLC22A1;CHRNA9;TRPM8;SLC22A2 GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport GLRA3;SLC22A5;SLC22A8;TRPV3;SLC22A4;SLC22A3;CACNA1H;CHRNA7;TRPV2;TRPA1;GLRA1;CHRNA9;SLC22A1;CACNA1G;TRPM8;SLC22A2;KCNA1;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1 GO:0006855| drug transmembrane transport SLC22A1;ABCC1;SLC22A2;ABCG2;SLC22A3;SLC22A5;SLC47A1 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA9;GLRA1;TRPV1;GLRB;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0050905| neuromuscular process KCNA1;GLRB;GLRA1 GO:0042391| regulation of membrane potential GLRB;KCNA1;GLRA1;CACNA1G;CACNA1H GO:0051260| protein homooligomerization ACAT1;GLRA3;KCNA1;GLRA1;SLC22A1 GO:0007605| sensory perception of sound GPX1;SOD1;CHRNA9 GO:0034220| ion transmembrane transport CHRNA7;SLC22A4;GLRA3;TRPV1;GLRB;CHRNA9;TRPA1;GLRA1 GO:0055085| transmembrane transport SLC22A1;ABCC1;CACNA1G;TRPA1;KCNA1;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;SLC22A2;ABCG2;TRPV3;SLC22A4;CACNA1H;SLC22A3;SLC22A8;SLC22A5;SLC47A1;TRPV2 17733:[DB14011 DB00187] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00187|Esmolol ADRB1;CYP2D6 common genes CYP2D6 common pathways GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0001659| temperature homeostasis TRPV1;ADRB1;HTR2A;GPX1 GO:0009409| response to cold ADRB1;TRPM8;PPARG;TRPA1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0050873| brown fat cell differentiation ADRB1;PTGS2 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;ADRB1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1 GO:0019369| arachidonic acid metabolic process FAAH;ALOX15;DAGLA;CYP2D6;CYP1B1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;ADRB1;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 17734:[DB14011 DB03336] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03336|BIA COMT common genes common pathways GO:0032259| methylation COMT;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;COMT;CYP1A1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0007612| learning COMT;VDAC1;PTGS2 GO:0007614| short-term memory CHRNA7;COMT GO:0008210| estrogen metabolic process CYP1B1;COMT GO:0048265| response to pain TRPV1;COMT;TRPA1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;COMT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0032502| developmental process COMT;CYP1A1 GO:0043627| response to estrogen stimulus PPARG;COMT GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;COMT GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;COMT;ACAT1;AANAT;PTGS2;CYP1A2 GO:0007565| female pregnancy COMT;IDO1 17735:[DB14011 DB06817] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06817|Raltegravir pol;UGT1A1 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1;UGT1A1 GO:0007584| response to nutrient HMGCR;CNR1;UGT1A1;PPARG GO:0001889| liver development CYP1A1;UGT1A1;ACAT1 GO:0045471| response to ethanol UGT1A1;SOD1;CNR1;HMGCR;OPRM1;CAT GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0008152| metabolic process ACAT1;UGT1A1;SMPD1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;UGT1A1;CYP1A1;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;UGT1A1;CYP2C9;CYP1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;UGT1A1;TRPA1;PPARG;CYP1A1 GO:0032496| response to lipopolysaccharide IDO1;UGT1A1;CYP1A1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0042594| response to starvation PPARG;UGT1A1;ACAT1 GO:0042493| response to drug ABCG2;UGT1A1;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 17736:[DB14011 DB04715] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04715|IMIDAZOPYRIDAZIN 1 PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;PIM1;CAT;GPX1 GO:0006915| apoptotic process VDAC1;GPX1;PIM1 GO:0008283| cell proliferation HTR1A;PIM1;GPX1;CYP1A1 17737:[DB14011 DB09098] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09098|Somatrem GHR;IGF1R common genes common pathways GO:0032355| response to estradiol stimulus GHR;CAT;PTGS2;CYP1A2 GO:0051262| protein tetramerization CAT;IGF1R;HMGCR GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B;GHR GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;IGF1R;HMGCR;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;IGF1R;PTGS2;HMGCR;HTR1A;HTR2A GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15;GHR GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;IGF1R;OPRM1;CNR2;CHRNA7 GO:0032870| cellular response to hormone stimulus CACNA1H;GHR GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;IGF1R GO:0040014| regulation of multicellular organism growth SOD1;GHR GO:0045740| positive regulation of DNA replication PLA2G1B;IGF1R GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;GHR GO:0006955| immune response OPRD1;CNR2;IGF1R 17738:[DB14011 DB06892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;MAP2K1;HTR2A;GPR55;HMGCR;OPRM1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;MAP2K1;PLA2G1B GO:0010628| positive regulation of gene expression MAP2K1;TRPV4 GO:0048538| thymus development MAP2K1;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;MAP2K1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;MAP2K1;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;MAP2K1 GO:0007507| heart development PPARG;MAP2K1 17739:[DB14011 DB05553] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05553|Regrelor P2RY12 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;P2RY12 GO:0070588| calcium ion transmembrane transport TRPV3;CACNA1H;OPRM1;TRPV2;P2RY12;CHRNA7;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;P2RY12;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0065009| regulation of molecular function P2RY12;TRPV1 GO:0051924| regulation of calcium ion transport OPRD1;P2RY12 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;P2RY12 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;P2RY12;PPARG;GPR18 GO:0071407| cellular response to organic cyclic compound P2RY12;CYP1B1;CYP1A1 GO:0071318| cellular response to ATP P2RY12;SOD1;PTGS2;TRPV1 17740:[DB14011 DB14031] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14031|Tretamine BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCHE;PPARG;CYP1B1 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;BCHE;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 17741:[DB14011 DB00013] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;PLAUR GO:0001525| angiogenesis PTGS2;SERPINE1;CYP1B1 GO:0061045| negative regulation of wound healing HMGCR;SERPINE1 GO:0042953| lipoprotein transport LRP2;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;LRP2 GO:0007399| nervous system development SMPD1;GLRB;LRP2 GO:0007507| heart development PPARG;LRP2 GO:0008283| cell proliferation LRP2;GPX1;HTR1A;CYP1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;PLG;CYP1B1 GO:1902042| GPX1;SERPINE1 GO:0001523| retinoid metabolic process LRP2;NAPEPLD GO:0030336| negative regulation of cell migration SERPINE1;CYP1B1 GO:0050729| positive regulation of inflammatory response TRPV4;SERPINE1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;PLAU;PLAUR;CACNA1I;PLA2G1B GO:0010811| positive regulation of cell-substrate adhesion ALOX15;NID1 GO:0051702| interaction with symbiont PLG;GPX1 GO:0033629| negative regulation of cell adhesion mediated by integrin SERPINE1;CYP1B1 GO:0007623| circadian rhythm SERPINE1;AANAT GO:0042060| wound healing OPRM1;ALOX15;SERPINB2 GO:0042127| regulation of cell proliferation PLAU;PTGS2;PTGS1 GO:0043312| neutrophil degranulation CAT;ALOX5;PLAU;PLAUR GO:0007155| cell adhesion NID1;CYP1B1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;SERPINB2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;SERPINB2;PLAUR GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;PLA2G1B;PPARG GO:0002576| platelet degranulation PLG;SOD1;SERPINE1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;SERPINE1 GO:0050769| positive regulation of neurogenesis OPRM1;LRP2 GO:0007283| spermatogenesis CNR1;SOD1;SERPINA5 GO:0001666| response to hypoxia CYP1A1;PLAU;PLAT;CAT;CHRNA7 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4;LRP2 GO:0007605| sensory perception of sound SOD1;LRP2;GPX1 GO:0043388| positive regulation of DNA binding PPARG;PLAUR 17742:[DB14011 DB05045] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05045|Obinepitide NPY4R;NPY2R common genes common pathways GO:0051967| negative regulation of synaptic transmission, glutamatergic NPY2R;HTR2A GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;GLRB;NPY2R;NPY4R;GLRA1 GO:0007626| locomotory behavior NPY2R;SOD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway NPY4R;NPY2R;GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0007568| aging CYP1A1;NPY2R;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;VDAC1;GLRB;NPY2R;NPY4R;GLRA1;CACNA1G GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;NPY2R GO:0045987| positive regulation of smooth muscle contraction PTGS2;NPY2R GO:0030818| negative regulation of cAMP biosynthetic process NPY2R;OPRM1 GO:0001662| behavioral fear response VDAC1;NPY2R;HTR1A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV1;TRPV4;NPY2R GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;NPY2R GO:0010811| positive regulation of cell-substrate adhesion ALOX15;NPY2R GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;NPY2R;PLA2G1B;NPY4R;PPARG;GPR18;SMPD1 GO:0065009| regulation of molecular function TRPV1;NPY2R 17743:[DB14011 DB08672] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DPP4 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043542| endothelial cell migration CYP1B1;DPP4 17744:[DB14011 DB07988] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07988|2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2YL)-UREIDO]-N-METHYL-3-PENTAFLUOROPHENYL-PROPIONAMIDE MMP3 common genes common pathways 17745:[DB14011 DB01863] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01863|Inositol 1,3,4,5-Tetrakisphosphate AKT1;PLEKHA4;BTK;DAPP1;ITPKA;CYTH2;CYTH3;PDPK1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKT1;HMGCR GO:1902176| GPX1;AKT1 GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1;BTK GO:0045893| positive regulation of transcription, DNA-dependent AKT1;PPARG GO:0032094| response to food CYP1A1;OPRM1;AKT1 GO:0071407| cellular response to organic cyclic compound AKT1;CYP1B1;CYP1A1 GO:0045087| innate immune response BTK;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;AKT1 GO:0008284| positive regulation of cell proliferation AKT1;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;AKT1;HMGCR;PTGS2 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;AKT1;OPRM1;GLRA3;TRPV1;GLRB;GLRA1 GO:0042127| regulation of cell proliferation BTK;PTGS1;PTGS2 GO:0071356| cellular response to tumor necrosis factor AKT1;TRPV1 GO:0015758| glucose transport PLA2G1B;AKT1 GO:0010033| response to organic substance BTK;CYP1A2;PTGS2;AKT1;SOD1;CYP1A1;PPARG;TRPA1 GO:0045766| positive regulation of angiogenesis PDPK1;CYP1B1;CHRNA7 GO:0006915| apoptotic process VDAC1;BTK;GPX1;AKT1 GO:0042593| glucose homeostasis CNR1;AKT1;PPARG;TRPV4 GO:0002376| immune system process IDO1;BTK GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;AKT1;PTGS2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;AKT1;TRPV1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;AKT1;SLC29A1 GO:0007568| aging CYP1A1;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;AKT1;CAT GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1;AKT1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;AKT1;OPRD1 GO:0006954| inflammatory response AKT1;PTGS2;CNR2;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0009408| response to heat TRPV2;SOD1;TRPV3;AKT1;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;BTK;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;AKT1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;AKT1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;AKT1;PTGS2 GO:0043524| negative regulation of neuron apoptosis SOD1;PDPK1 GO:0010629| negative regulation of gene expression AKT1;OPRD1 GO:0007399| nervous system development AKT1;SMPD1;GLRB GO:1990090| AKT1;TRPV1 GO:0071260| cellular response to mechanical stimulus PTGS2;AKT1 GO:0043065| positive regulation of apoptotic process PTGS2;AKT1;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0035556| intracellular signal transduction BTK;AKT1;PLA2G1B;PDPK1 GO:0000060| protein import into nucleus, translocation OPRD1;AKT1 GO:0048469| cell maturation BTK;PPARG GO:0006351| transcription, DNA-dependent BTK;PDPK1;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG;AKT1 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;AKT1 GO:0071276| cellular response to cadmium ion SOD1;AKT1;CYP1A2 GO:0006809| nitric oxide biosynthetic process AKT1;CYP1B1 GO:0008283| cell proliferation CYP1A1;AKT1;HTR1A;GPX1 GO:0009725| response to hormone stimulus ACAT1;AKT1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;AKT1;PTGS2 GO:0007165| signal transduction CACNA1I;PLA2G1B;ITPKA;GPR18;PPARG;SMPD1;DAPP1;CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;AKT1;CNR2;OPRM1 GO:0065009| regulation of molecular function TRPV1;CYTH2;CYTH3 GO:0014065| phosphatidylinositol 3-kinase cascade AKT1;HTR2A GO:0045907| positive regulation of vasoconstriction PTGS2;AKT1;HTR2A GO:0032869| cellular response to insulin stimulus AKT1;PPARG;PDPK1;PLA2G1B GO:0001649| osteoblast differentiation CAT;AKT1 GO:0031999| negative regulation of fatty acid beta-oxidation CNR1;AKT1 GO:0032287| peripheral nervous system myelin maintenance SOD1;AKT1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;AKT1 17746:[DB14011 DB07176] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;TTR GO:0006810| transport TTR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process NAPEPLD;TTR 17747:[DB14011 DB08515] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08515|(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA6;PSMA7;PSMB1;PSMB2;PSMB3;PSMB4;PSMB5;PSMB6;PSMB7 common genes common pathways GO:0055085| transmembrane transport PSMA2;TRPM8;ABCG2;PSMA3;CACNA1I;TRPV4;VDAC1;TRPV1;PSMB6;PSMA1;TRPA1;PSMA7;ABCC1;PSMA6;CACNA1G;TRPV2;PSMB2;PSMA4;PSMB4;PSMA5;PSMB1;PSMB3;TRPV3;CACNA1H;PSMB7;PSMB5 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;PSMB5;SOD1 GO:0002376| immune system process IDO1;PSMA1 GO:0002862| negative regulation of inflammatory response to antigenic stimulus GPX1;PSMB4 GO:0010243| response to organic nitrogen TRPV1;PTGS2;PSMB2 GO:0009615| response to virus CYP1A1;PSMA2 GO:0043312| neutrophil degranulation ALOX5;CAT;PSMB7;PSMA5;PSMB1;PSMA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;PSMB2;ACAT1;AANAT GO:0016032| viral reproduction HTR2A;PSMB2;PSMB4;PSMA4;PSMB3;PSMB1;PSMB5;PSMB7;PSMA3;PSMB6;VDAC1;PSMA7 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PSMA6;PLA2G1B GO:0050727| regulation of inflammatory response PSMA6;PTGS2 17748:[DB14011 DB04648] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04648|S-propylamine-L-cysteine ARG1 common genes common pathways GO:0043434| response to peptide hormone stimulus TRPV1;ARG1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;ARG1 GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0010043| response to zinc ion AANAT;ARG1 GO:0010269| response to selenium ion ARG1;GPX1 GO:0048678| response to axon injury SOD1;ARG1 GO:0001889| liver development ARG1;ACAT1;CYP1A1 GO:0007565| female pregnancy IDO1;ARG1 GO:0009635| response to herbicide CYP1A1;ARG1 GO:0002376| immune system process IDO1;ARG1 GO:0007568| aging CAT;ARG1;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CYP1A1 GO:0009611| response to wounding GPX1;ARG1;CYP1A1 GO:0042130| negative regulation of T cell proliferation ARG1;IDO1 GO:0043200| response to amino acid stimulus ARG1;GLRA3;GLRB GO:0046686| response to cadmium ion ARG1;CAT GO:0043312| neutrophil degranulation CAT;ARG1;ALOX5 GO:0045087| innate immune response ARG1;PPARG GO:0070207| protein homotrimerization ARG1;TRPM8 GO:0030324| lung development CYP1A2;ARG1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E CAT;ARG1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1;ARG1 GO:0033189| response to vitamin A CAT;ARG1;PPARG;CYP1A1 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0042493| response to drug ARG1;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 17749:[DB14011 DB03306] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03306|RU78300 SRC common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process SRC;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;SRC;CHRNA7 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0045087| innate immune response PPARG;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0043066| negative regulation of apoptotic process CAT;SRC;GPX1;SOD1;PTGS2;HMGCR GO:0009615| response to virus SRC;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;SRC;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2 GO:0016236| macroautophagy SRC;VDAC1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0007165| signal transduction SRC;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0045453| bone resorption SRC;GPR55 GO:0008283| cell proliferation CYP1A1;GPX1;SRC;HTR1A GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0043065| positive regulation of apoptotic process SRC;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0042542| response to hydrogen peroxide SRC;GPX1;CAT;SOD1;TRPA1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0031667| response to nutrient levels SRC;SOD1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0016032| viral reproduction SRC;HTR2A;VDAC1 17750:[DB14011 DB00137] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00137|Lutein ALB common genes common pathways GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0001895| retina homeostasis SOD1;ALB 17751:[DB14011 DB07785] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07785|1-{(1R,2S)-2-HYDROXY-1-[2-(2-NAPHTHYLOXY)ETHYL]PROPYL}-1H-IMIDAZONE-4-CARBOXAMIDE ADA common genes common pathways GO:0030324| lung development CYP1A2;ADA GO:0033197| response to vitamin E ADA;CAT GO:0007155| cell adhesion CYP1B1;ADA GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;ADA;GPX1;CAT GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ADA;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0043278| response to morphine CNR1;OPRM1;ADA GO:0050728| negative regulation of inflammatory response CNR2;ADA GO:0007568| aging HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;ADA;CAT;CYP1A1 GO:0001666| response to hypoxia CAT;CHRNA7;ADA;CYP1A1 GO:0001889| liver development ACAT1;ADA;CYP1A1 GO:0042542| response to hydrogen peroxide TRPA1;CAT;ADA;GPX1;SOD1 GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0001890| placenta development PPARG;ADA;SOD1 17752:[DB14011 DB01345] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01345|Potassium cation ATP1A1 common genes common pathways GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;ATP1A1;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;ATP1A1;PTGS1 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0086002| CACNA1G;ATP1A1 GO:0034220| ion transmembrane transport CHRNA7;ATP1A1;GLRA3;TRPV1;GLRB;GLRA1;TRPA1 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;CAT;ATP1A1;SOD1;HTR2A;CYP1A2;PTGS2 17753:[DB14011 DB11338] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0055093| response to hyperoxia CYP1A1;COL1A1;CAT GO:0009308| amine metabolic process CYP1A1;VCAM1 GO:0016525| negative regulation of angiogenesis PPARG;CXCL10 GO:0035094| response to nicotine VCAM1;CNR1;CHRNA7 GO:0060326| cell chemotaxis VCAM1;ABCC1 GO:0042493| response to drug ABCG2;COL1A1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;COL1A1 GO:0007517| muscle organ development CXCL10;CACNA1H GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;VCAM1;CYP3A4;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9 GO:0009615| response to virus CXCL10;CYP1A1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;CXCL10 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CXCL10;PPARG;PLA2G1B GO:0071300| cellular response to retinoic acid COL1A1;PPARG GO:0009612| response to mechanical stimulus PPARG;COL1A1;TRPV4 GO:0007155| cell adhesion VCAM1;CYP1B1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CXCL10 GO:0042060| wound healing OPRM1;COL1A1;ALOX15 GO:0032496| response to lipopolysaccharide CXCL10;CYP1A1;IDO1;CYP1A2;OPRM1;CNR2;PTGS2;VCAM1;CNR1 GO:0030199| collagen fibril organization CYP1B1;COL1A1 GO:0071230| cellular response to amino acid stimulus GLRA1;COL1A1 GO:0071306| cellular response to vitamin E COL1A1;PPARG GO:0001666| response to hypoxia CYP1A1;VCAM1;CAT;CHRNA7 GO:0071356| cellular response to tumor necrosis factor TRPV1;COL1A1;VCAM1 GO:0051591| response to cAMP AANAT;COL1A1 GO:0007605| sensory perception of sound COL1A1;SOD1;GPX1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;COL1A1 GO:0007186| G-protein coupled receptor signaling pathway CXCL10;GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0034605| cellular response to heat CXCL10;TRPV4;TRPV1;PTGS2 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;VCAM1;CNR1;SOD1;HTR2A;CAT;CYP1A1 GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;TRPV1;IDO1;ALOX15;CXCL10 GO:0016032| viral reproduction VDAC1;VCAM1;HTR2A GO:0006955| immune response CXCL10;OPRD1;CNR2 GO:0045859| regulation of protein kinase activity SOD1;CXCL10 GO:0031667| response to nutrient levels COL1A1;SOD1 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;TRPA1;COL1A1 GO:0060351| cartilage development involved in endochondral bone morphogenesis TRPV4;COL1A1 GO:0009409| response to cold TRPM8;CXCL10;PPARG;TRPA1 GO:0001503| ossification COL1A1;ALOX15 GO:0071260| cellular response to mechanical stimulus PTGS2;COL1A1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CXCL10;TRPV1 GO:0045471| response to ethanol VCAM1;SOD1;CNR1;OPRM1;HMGCR;CAT GO:0010043| response to zinc ion AANAT;VCAM1 GO:0061844| CXCL10;PLA2G1B GO:0007584| response to nutrient VCAM1;CNR1;HMGCR;PPARG;COL1A1 GO:0033280| response to vitamin D PTGS2;CXCL10 GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;CXCL10;SMPD1;PLA2G1B;CACNA1I GO:0010332| response to gamma radiation GPX1;CXCL10 GO:0065009| regulation of molecular function CSF2RA;TRPV1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;CXCL10 GO:0043434| response to peptide hormone stimulus TRPV1;COL1A1 GO:0007601| visual perception GLRB;COL1A1;CYP1B1;GLRA1;CRYZ GO:0001649| osteoblast differentiation CAT;COL1A1 17754:[DB14011 DB06859] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06859|N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE F2 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0061844| PLA2G1B;F2 17755:[DB14011 DB08490] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08490|CTS-1027 MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13;ALOX15 17756:[DB14011 DB08775] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08775|Nα-[(Benzyloxy)carbonyl]-N-[(2S)-4-fluoro-3-oxo-2-butanyl]-L-tyrosinamide CTSF common genes common pathways 17757:[DB14011 DB09499] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09499|Thiosulfuric acid TST common genes common pathways GO:0030855| epithelial cell differentiation VDAC1;TST;PPARG 17758:[DB14011 DB00166] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0006954| inflammatory response ALOX5;PTGS1;LIAS;PTGS2;CNR2;TRPV1;ALOX15;IDO1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;POR GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;PTGS1;NAAA;GPX1;PPARG;CYP2C9;LIPT1;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C19;POR;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0070988| demethylation POR;CYP1A1 GO:0007584| response to nutrient PPARG;POR;CNR1;HMGCR GO:0019395| fatty acid oxidation POR;PPARG GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;SLC5A6;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0055114| oxidation-reduction process POR;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP2C9;CYP1A1;CRYZ;ALOX5;GPX1;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;POR;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0022900| electron transport chain GSR;IDO1;POR;CYP1A2 GO:0043066| negative regulation of apoptotic process POR;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0009812| flavonoid metabolic process CYP1A1;POR GO:0032496| response to lipopolysaccharide CNR2;PTGS2;CYP1A2;OPRM1;CNR1;LIAS;CYP1A1;IDO1 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;SLC5A6;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;CACNA1H;TRPV3;TRPV2 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;LIAS GO:0006810| transport CACNA1I;TRPV1;ABCG2;SLC5A6;ABCC1;TRPV2 17759:[DB14011 DB07550] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07550|2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDE F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PPARG;GPR18;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 17760:[DB14011 DB04149] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways GO:0030593| neutrophil chemotaxis PDE4D;PDE4B;PLA2G1B GO:0007568| aging PDE4D;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;PDE4B;CNR2;OPRM1;PDE4D;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0002027| regulation of heart rate CACNA1G;PDE4D GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;PDE4D;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;PDE4B;CACNA1I;PLA2G1B GO:0006939| smooth muscle contraction PDE4D;HTR2A 17761:[DB14011 DB08370] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways GO:0031667| response to nutrient levels SOD1;GSTP1 GO:1904706| PPARG;GSTP1 GO:0045471| response to ethanol GSTP1;HMGCR;OPRM1;CNR1;SOD1;CAT GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;GSTP1;CYP1B1 GO:0008152| metabolic process ACAT1;GSTP1;SMPD1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0009636| response to toxin CAT;GPX1;CYP1B1;GSTP1;CYP1A1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0006749| glutathione metabolic process GPX1;SOD1;GSR;GSTP1 GO:0032869| cellular response to insulin stimulus GSTP1;PLA2G1B;PPARG GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;GSR;GSTP1 GO:0000302| response to reactive oxygen species SOD1;GPX1;CAT;GSTP1 GO:0043312| neutrophil degranulation GSTP1;CAT;ALOX5 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;GSTP1 GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;GSTP1 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSTP1;GSR 17762:[DB14011 DB06785] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06785|Ganirelix GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GNRHR;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0007165| signal transduction HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;GNRHR;CACNA1I;PLA2G1B 17763:[DB14011 DB13620] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0034220| ion transmembrane transport ATP4B;GLRA3;ATP1A1;CHRNA7;SLC12A1;TRPA1;GLRA1;FXYD2;GLRB;ATP4A;TRPV1 GO:0086002| CACNA1G;ATP1A1 GO:0055085| transmembrane transport TRPV2;SLC12A1;CACNA1H;TRPV3;VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0006810| transport SLC12A1;TRPV2;FXYD2;ABCC1;ABCG2;CACNA1I;ATP4A;TRPV1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ATP1A1 GO:0010243| response to organic nitrogen TRPV1;PTGS2;ATP4B GO:0042127| regulation of cell proliferation PTGS1;PTGS2;FXYD2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;ATP4B;CYP1A2;CNR1;IDO1;CYP1A1 GO:0007155| cell adhesion ATP4B;CYP1B1 GO:0006811| ion transport TRPM8;ATP4A;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPA1;GLRA1;FXYD2;CACNA1G;CHRNA7;SLC12A1;TRPV2;ATP1A1;GLRA3;TRPV3;ATP4B;CACNA1H GO:0008217| regulation of blood pressure SOD1;ATP1A1;PTGS2;PTGS1;PPARG GO:1902476| SLC12A1;GLRA3;GLRB;GLRA1 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 17764:[DB14011 DB01191] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01191|Dexfenfluramine SLC6A4;HTR2C;CYP2D6;CYP1A2;CYP2E1 common genes CYP1A2;CYP2D6 common pathways GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;ALOX15;DAGLA;CYP2D6;CYP1B1 GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2C;HTR2A GO:0010243| response to organic nitrogen CYP2E1;PTGS2;TRPV1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0042493| response to drug CYP1A2;PTGS2;CYP2E1;HTR2A;SOD1;SLC6A4;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;HTR2C GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP2E1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007626| locomotory behavior HTR2C;OPRM1;SOD1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0007623| circadian rhythm SLC6A4;AANAT GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2C;OPRM1;OPRD1;HTR2A GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0010628| positive regulation of gene expression SLC6A4;TRPV4 GO:0001666| response to hypoxia CAT;SLC6A4;CHRNA7;CYP1A1 GO:0010193| response to ozone CYP2E1;CAT GO:0010033| response to organic substance SLC6A4;CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger HTR2C;GPR18;GPR55 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;HTR2C;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0055085| transmembrane transport ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1;SLC6A4;TRPV2;CACNA1H;TRPV3 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;TRPV4;HTR2C;TRPM8 GO:0007210| serotonin receptor signaling pathway HTR2C;HTR1A;HTR2A GO:0051260| protein homooligomerization GLRA1;ACAT1;SLC6A4;GLRA3 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP2E1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0051209| release of sequestered calcium ion into cytosol HTR2A;HTR2C;TRPV1;TRPA1 GO:0032355| response to estradiol stimulus CAT;SLC6A4;CYP1A2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18;HTR2C GO:0010468| regulation of gene expression CYP1A2 GO:0007268| synaptic transmission GLRA1;CACNA1G;HTR2C;GLRB;VDAC1;HTR2A;GLRA3;OPRD1;OPRM1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0042310| vasoconstriction SLC6A4;HTR1A GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0042136| neurotransmitter biosynthetic process SLC6A4;DAGLA GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A;HTR2C GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0051100| negative regulation of binding CYP2D6 GO:0045471| response to ethanol CYP2E1;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C;HTR2A GO:0007584| response to nutrient PPARG;SLC6A4;HMGCR;CNR1 GO:0001662| behavioral fear response VDAC1;HTR2C;HTR1A GO:0009636| response to toxin CYP1A1;CYP1B1;GPX1;SLC6A4;CAT GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;PTGS2;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0007165| signal transduction HTR2C;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0007420| brain development ACAT1;SLC6A4 GO:0097267| CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP1A2 GO:0007610| behavior HTR2C;HTR2A;HTR1A GO:0007613| memory CHRNA7;SLC6A4;PTGS2;HTR2A;CNR1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 17765:[DB14011 DB05137] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes CHRNA7 common pathways GO:0070588| calcium ion transmembrane transport TRPV3;OPRM1;CACNA1H;TRPV2;CHRNA7;CACNA1G;TRPA1;CHRNA9;CHRNA10;TRPV4;CACNA1I;TRPV1;TRPM8 GO:1904645| CHRNA7 GO:1900273| CHRNA7 GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA10;CACNA1I;PLA2G1B;GPR18;PPARG;CHRNA9;SMPD1 GO:0050890| cognition CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration CHRNA10;TRPV1;TRPV4;CHRNA9;HTR2A;OPRM1 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0006812| cation transport CHRNA9;TRPM8 GO:0006811| ion transport TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;CHRNA10;CHRNA9;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CHRNA10;CHRNA9 GO:1902430| CHRNA7 GO:0006816| calcium ion transport CHRNA7;TRPV2;TRPV3;CACNA1H;TRPM8;CHRNA10;CACNA1I;TRPV4;TRPV1;TRPA1;CHRNA9;CACNA1G GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPV4;TRPM8 GO:1901214| CHRNA7 GO:0007605| sensory perception of sound CHRNA9;GPX1;SOD1 GO:0098815| CHRNA7 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:1902991| CHRNA7 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:0095500| CHRNA7 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;TRPV1;GLRB;CHRNA10;CHRNA9;TRPA1;GLRA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:1905920| CHRNA7 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;CHRNA10 GO:0007611| learning or memory CNR1;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;CHRNA9;CHRNA10;GLRB;TRPV1 GO:0007614| short-term memory CHRNA7 GO:1905144| CHRNA7 GO:1905906| CHRNA7 GO:0050893| sensory processing CHRNA7 GO:0035094| response to nicotine CHRNA7;CNR1 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0050808| synapse organization CHRNA7 17766:[DB14011 DB14071] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14071|Desmethylsertraline ABCB1 common genes common pathways GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006810| transport ABCB1;CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;ABCB1 17767:[DB14011 DB04459] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways GO:0002576| platelet degranulation CFD;SOD1 GO:0043312| neutrophil degranulation CAT;CFD;ALOX5 GO:0045087| innate immune response PPARG;CFD GO:0002376| immune system process IDO1;CFD 17768:[DB14011 DB07101] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07101|PD-0325901 MAP2K1 common genes common pathways GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;MAP2K1;PTGS2;OPRM1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;MAP2K1;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0010629| negative regulation of gene expression MAP2K1;OPRD1 GO:0007507| heart development PPARG;MAP2K1 GO:0010628| positive regulation of gene expression TRPV4;MAP2K1 GO:0000187| activation of MAPK activity SOD1;MAP2K1;CHRNA7;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;MAP2K1;CHRNA7;TRPV4;ALOX15 GO:0048538| thymus development MAP2K1;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;MAP2K1 17769:[DB14011 DB04754] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0006955| immune response OPRD1;CNR2;PNP GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;PPARG;PNP;CYP1A1;SMPD1;ABCC1 GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 17770:[DB14011 DB03695] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03695|Piritrexim DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1;CYP2C9;CYP1A1;DHFR;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1 17771:[DB14011 DB01979] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01979|Methyl alpha-D-mannoside MBL2 common genes common pathways GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;MBL2 GO:0002376| immune system process MBL2;IDO1 GO:0045087| innate immune response MBL2;PPARG GO:0050830| defense response to Gram-positive bacterium MBL2;PLA2G1B 17772:[DB14011 DB02845] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02845|Methylphosphinic Acid BCHE;ACHE;BCHE common genes common pathways GO:0007399| nervous system development ACHE;SMPD1;GLRB GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;ACHE GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;BCHE GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0007612| learning PTGS2;VDAC1;BCHE GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;BCHE;TRPA1;PPARG;CYP1A1;ABCG2 GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0051262| protein tetramerization CAT;HMGCR;ACHE 17773:[DB14011 DB00915] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes CHRNA7 common pathways GO:0046219| indolalkylamine biosynthetic process AANAT;DDC GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;CHRNA4;GLRA1;CACNA1G;VDAC1;GLRB GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0008542| visual learning HMGCR;DRD2 GO:1902430| CHRNA7 GO:0006816| calcium ion transport TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;GRIN3A;TRPA1;TRPV2;CHRNA4;CHRNA7;CACNA1H;TRPV3 GO:0001964| startle response GLRA1;GLRB;DRD2 GO:0045776| negative regulation of blood pressure DRD2;CNR1 GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1;DRD2;GRIN3A;MAOB GO:0048678| response to axon injury DRD2;SOD1 GO:0019233| sensory perception of pain TRPV1;TRPA1;CHRNA4;OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0007399| nervous system development SMPD1;GLRB;CHRNA3 GO:0060078| regulation of postsynaptic membrane potential CHRNA7 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0071312| cellular response to alkaloid DDC;TRPV1 GO:0001659| temperature homeostasis DRD2;TRPV1;GPX1;HTR2A GO:0048148| behavioral response to cocaine DRD2;HTR2A GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0006855| drug transmembrane transport ABCC1;SLC22A1;SLC22A2;ABCG2 GO:0014854| response to inactivity DRD2;CAT GO:0006811| ion transport GLRA3;CACNA1H;TRPV3;CHRNA7;CHRNA4;TRPV2;GRIN3A;TRPA1;GLRA1;CACNA1G;SLC22A1;SLC22A2;TRPM8;VDAC1;TRPV4;CHRNA3;CACNA1I;GLRB;TRPV1 GO:0009636| response to toxin DDC;CAT;GPX1;CYP1A1;MAOB;CYP1B1;DRD2 GO:0010269| response to selenium ion GPX1;MAOB GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0006812| cation transport SLC22A1;SLC22A2;TRPM8 GO:0008285| negative regulation of cell proliferation CYP1B1;DRD2;PPARG;OPRM1;PTGS2 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0050890| cognition CHRNA4;CHRNA7 GO:0001975| response to amphetamine SOD1;CNR2;DRD2 GO:0097061| dendritic spine organization CHRNA7 GO:0007165| signal transduction CHRNA7;CHRNA4;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;DRD2;CHRNA3;CACNA1I;GPR18;PPARG;SMPD1 GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0070588| calcium ion transmembrane transport GRIN3A;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:1904645| CHRNA7 GO:0050482| arachidonic acid secretion PLA2G1B;DRD2 GO:1900273| CHRNA7;DRD2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP1A1;CYP2C9;MAOB;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0050808| synapse organization CHRNA7 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;MAOB;ABCG2;DRD2 GO:0022900| electron transport chain CYP1A2;MAOB;IDO1;GSR GO:0035640| exploration behavior HTR1A;CHRNA4 GO:0050893| sensory processing CHRNA7 GO:0035094| response to nicotine CHRNA4;CHRNA7;CNR1;DRD2 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0043278| response to morphine DRD2;OPRM1;CNR1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;CHRNA4;SLC29A1;GLRA3;OPRM1;TRPV1;GLRB;CHRNA3;DRD2;GRIN3A;GLRA1 GO:0007614| short-term memory CHRNA7 GO:1905144| CHRNA7;CHRNA3 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:1905906| CHRNA7 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0001508| regulation of action potential CACNA1G;GLRA1;CHRNA4 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;MAOB;CYP1A1;IDO1 GO:0007623| circadian rhythm DDC;AANAT GO:0007611| learning or memory CHRNA7;CNR1 GO:0007628| adult walking behavior DRD2;GLRB;GLRA1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;DRD2;PLA2G1B GO:0007626| locomotory behavior CHRNA4;SOD1;OPRM1;CHRNA3;DRD2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0055085| transmembrane transport TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;SLC22A2;CACNA1G;SLC22A1;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;TRPV4;DRD2 GO:1905920| CHRNA7 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B GO:0042220| response to cocaine SMPD1;DRD2;OPRM1;CNR1 GO:0095500| CHRNA4;CHRNA7;CHRNA3 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1;MAOB GO:0034220| ion transmembrane transport GLRA3;CHRNA4;CHRNA7;GRIN3A;GLRA1;TRPA1;GLRB;CHRNA3;TRPV1 GO:0009416| response to light stimulus DRD2;AANAT GO:1902991| CHRNA7 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;CHRNA4 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD2;GPR18;GPR55 GO:0014059| regulation of dopamine secretion DRD2;CHRNA4;HTR2A GO:0140059| CHRNA7 GO:0001666| response to hypoxia DRD2;CYP1A1;CHRNA7;CAT;CHRNA4 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PPARG;GPR18;DRD2 GO:0098815| CHRNA7 GO:0071363| cellular response to growth factor stimulus TRPV1;OPRD1;CAT;DDC GO:0051209| release of sequestered calcium ion into cytosol HTR2A;DRD2;TRPV1;TRPA1 GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:0042391| regulation of membrane potential CHRNA3;GLRB;CACNA1G;GLRA1;CHRNA4;CACNA1H GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;TRPV4;DRD2;TRPM8 GO:1901214| CHRNA7 GO:0006979| response to oxidative stress CAT;CHRNA4;GPX1;PTGS1;SOD1;PTGS2 17774:[DB14011 DB02877] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02877|Arotinoid acid RARB common genes common pathways GO:0001657| ureteric bud development CAT;RARB GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RARB GO:0006355| regulation of transcription, DNA-dependent PPARG;RARB GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;RARB;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARB;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;RARB GO:0008285| negative regulation of cell proliferation RARB;CYP1B1;PPARG;OPRM1;PTGS2 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;RARB;CACNA1I;PLA2G1B GO:0022008| neurogenesis RARB;DAGLA GO:0043065| positive regulation of apoptotic process IDO1;RARB;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0043401| steroid hormone mediated signaling pathway RARB;PPARG GO:0006351| transcription, DNA-dependent PPARG;RARB 17775:[DB14011 DB08454] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways GO:0043066| negative regulation of apoptotic process CAT;GPX1;CAMK1D;SOD1;HMGCR;PTGS2 GO:0032793| positive regulation of CREB transcription factor activity CAMK1D;OPRD1 GO:0008152| metabolic process SMPD1;CAMK1D;ACAT1 GO:0035556| intracellular signal transduction CAMK1D;PLA2G1B GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1;CAMK1D GO:0007399| nervous system development GLRB;SMPD1;CAMK1D GO:0010976| positive regulation of neuron projection development CAMK1D;CNR1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;CAMK1D;PTGS2;CNR2 17776:[DB14011 DB07469] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07469|(3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1G;CACNA1I;MYH14 GO:0007605| sensory perception of sound SOD1;GPX1;MYH14 17777:[DB14011 DB02373] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02373|Adenosine Monotungstate FHIT common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;FHIT GO:0006915| apoptotic process VDAC1;GPX1;FHIT GO:0006355| regulation of transcription, DNA-dependent PPARG;FHIT 17778:[DB14011 DB11792] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A7;CYP3A5;CYP3A4 common pathways GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;NAAA;GPX1;PTGS1;PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CAT;CYP3A43;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 17779:[DB14011 DB03856] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03856|L-Eflornithine ODC1 common genes common pathways GO:0001822| kidney development CAT;ODC1 GO:0009615| response to virus CYP1A1;ODC1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;ODC1;CHRNA7 17780:[DB14011 DB07339] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways GO:0022900| electron transport chain CYP1A2;NQO2;GSR;IDO1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;NQO2;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;GPX1;ALOX5;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C9;NQO2;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 17781:[DB14011 DB06471] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06471|Naxifylline ADORA1 common genes common pathways GO:0050965| detection of temperature stimulus involved in sensory perception of pain ADORA1;TRPV1;HTR2A GO:0006954| inflammatory response ADORA1;IDO1;ALOX15;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0007399| nervous system development ADORA1;SMPD1;GLRB GO:0001659| temperature homeostasis ADORA1;TRPV1;HTR2A;GPX1 GO:0045776| negative regulation of blood pressure CNR1;ADORA1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;ADORA1 GO:0045777| positive regulation of blood pressure CNR1;ADORA1 GO:0032229| negative regulation of synaptic transmission, GABAergic ADORA1;CNR2 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADORA1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;ADORA1;PPARG;SMPD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADORA1;OPRM1;OPRD1 GO:0050890| cognition ADORA1;CHRNA7 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;ADORA1 GO:0050728| negative regulation of inflammatory response CNR2;ADORA1 GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA1 GO:0035307| positive regulation of protein dephosphorylation SMPD1;ADORA1 GO:0043066| negative regulation of apoptotic process ADORA1;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;GLRA1;ADORA1;TRPV1;GLRB GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;ADORA1 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0016042| lipid catabolic process DAGLA;PLA2G1B;ADORA1;NAPEPLD GO:0097756| ADORA1;HMGCR;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;ADORA1;PPARG;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 17782:[DB14011 DB02776] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02776|1-Hexadecanosulfonic Acid FABP4 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent FABP4;PPARG GO:0071356| cellular response to tumor necrosis factor FABP4;TRPV1 GO:0050729| positive regulation of inflammatory response FABP4;TRPV4 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0050872| white fat cell differentiation FABP4;PPARG 17783:[DB14011 DB06726] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes CYP2D6 common pathways GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0042755| eating behavior OPRM1;OPRD1;ADRB3 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;ADRB2;OPRM1;CNR2;OPRD1;ADRB3;PLA2G1B;ADRB1;CACNA1I;PPARG;GPR18;SMPD1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0045453| bone resorption ADRB2;GPR55 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB3;ADRB2;CNR1 GO:0001659| temperature homeostasis ADRB3;ADRB1;TRPV1;GPX1;HTR2A GO:0009409| response to cold ADRB2;ADRB3;TRPM8;ADRB1;PPARG;TRPA1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0050873| brown fat cell differentiation ADRB1;ADRB3;PTGS2;ADRB2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;ADRB2 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;CNR2;OPRM1;ADRB3 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0007568| aging CYP1A1;ADRB3;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT GO:0007186| G-protein coupled receptor signaling pathway ADRB3;ADRB1;GPR18;PPARG;ADRB2;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;CYP2D6;DAGLA;FAAH GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ADRB2 GO:0046677| response to antibiotic CYP1A1;ADRB3;SOD1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1;ADRB3;ADRB2 17784:[DB14011 DB01933] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;PDPK1 GO:0006351| transcription, DNA-dependent PPARG;PDPK1 GO:0035556| intracellular signal transduction PDPK1;PLA2G1B GO:0043524| negative regulation of neuron apoptosis SOD1;PDPK1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PDPK1;PPARG 17785:[DB14011 DB08365] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08365|8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide WEE1 common genes common pathways 17786:[DB14011 DB01748] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01748|N-Benzyl-4-Sulfamoyl-Benzamide CA2 common genes common pathways GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1;CA2 GO:0001822| kidney development CAT;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 17787:[DB14011 DB03606] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways GO:0002027| regulation of heart rate CACNA1G;PDE4D GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction PDE4D;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;PDE4B GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B;PDE4B GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;PDE4B;OPRD1;PDE4D;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0007568| aging CAT;PDE4D;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CYP1A1 17788:[DB14011 DB07217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07217|N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide MAPK10 common genes common pathways GO:0010468| regulation of gene expression MAPK10;CYP1A2 GO:0009416| response to light stimulus AANAT;MAPK10 GO:0048511| rhythmic process PPARG;MAPK10;AANAT GO:0000187| activation of MAPK activity SOD1;CHRNA7;MAPK10;PLA2G1B GO:0042752| regulation of circadian rhythm MAPK10;PPARG GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;MAPK10;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7 17789:[DB14011 DB00244] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes PTGS2;ALOX5;PTGS1;PPARG common pathways GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0019430| removal of superoxide radicals SOD1;MPO GO:0071498| cellular response to fluid shear stress PTGS2 GO:1904706| PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;CHUK;IKBKB GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;CHUK;CNR2;PTGS2;IKBKB GO:0010942| positive regulation of cell death PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0006955| immune response CHUK;CNR2;OPRD1 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0048469| cell maturation PPARG GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0019233| sensory perception of pain OPRD1;CNR2;PTGS2;OPRM1;HTR2A;CNR1;TRPV1;TRPA1 GO:0006351| transcription, DNA-dependent PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:1990776| PTGS2 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;CAT;CHUK GO:0006919| activation of caspase activity PPARG GO:0009636| response to toxin CAT;CHUK;GPX1;CYP1B1;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071276| cellular response to cadmium ion CHUK;SOD1;CYP1A2 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0030224| monocyte differentiation PPARG GO:0055114| oxidation-reduction process CAT;MPO;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CHUK;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0032094| response to food MPO;OPRM1;CYP1A1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent CHUK;IKBKB;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0009750| response to fructose stimulus PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071455| cellular response to hyperoxia PPARG GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway GPX1;ALOX5;PTGS2;ALOX15 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0033194| response to hydroperoxide CHUK;GPX1 GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071284| cellular response to lead ion PTGS2 GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CHUK;MPO;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0030308| negative regulation of cell growth PPARG GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0045087| innate immune response CHUK;IKBKB;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0043312| neutrophil degranulation ALOX5;MPO;CAT GO:0009615| response to virus CHUK;IKBKB;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;IKBKB;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0071300| cellular response to retinoic acid PPARG GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;IKBKB;MPO;GPX1;CAT GO:0009612| response to mechanical stimulus TRPV4;PPARG;MPO GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0034612| response to tumor necrosis factor PTGS2 GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0042744| hydrogen peroxide catabolic process GPX1;MPO;CAT GO:0043200| response to amino acid stimulus GLRA3;CHUK;GLRB GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0071356| cellular response to tumor necrosis factor IKBKB;CHUK;TRPV1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CHUK;PPARG;CYP1A1;TRPA1 GO:2001300| ALOX5 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031000| response to caffeine PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0007568| aging CYP1A1;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;MPO;CAT GO:0015909| long-chain fatty acid transport PPARG GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1902219| PTGS2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0006979| response to oxidative stress MPO;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| PTGS2;CAT;PTGS1;GPX1;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0033993| response to lipid PPARG 17790:[DB14011 DB03977] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0055085| transmembrane transport TRPV2;CALM1;TRPV3;CACNA1H;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0006915| apoptotic process VDAC1;CYCS;GPX1 GO:0006936| muscle contraction CACNA1H;CALM1;GLRA1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CALM1;PPARG;GPR18 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;CYCS;SOD1;CYP3A4;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0002576| platelet degranulation SOD1;CALM1 GO:0035307| positive regulation of protein dephosphorylation CALM1;SMPD1 GO:0034599| cellular response to oxidative stress GPX1;CAT;SOD1;CYCS;GSR GO:0045333| cellular respiration CYCS;CYP1A2 GO:0002027| regulation of heart rate CALM1;CACNA1G GO:0051592| response to calcium ion CALM1;AANAT 17791:[DB14011 DB08418] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08418|(4aS,4bR,10bS,12aS)-12a-methyl-1,3-dioxo-2-(pyridin-3-ylmethyl)-1,2,3,4,4a,4b,5,6,10b,11,12,12a-dodecahydronaphtho[2,1-f]isoquinolin-8-yl sulfamate CA2 common genes common pathways GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CA2;PTGS2;CYP1A2;SOD1 GO:0001822| kidney development CA2;CAT GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 17792:[DB14011 DB03401] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03401|1D-myo-inositol 1,4,5-trisphosphate CYTH2;EPN1;PLCD1;RDX;SPTBN1;ITPR1;ITPKA common genes common pathways GO:0043087| regulation of GTPase activity RDX;SOD1 GO:0006816| calcium ion transport ITPR1;TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;TRPV3 GO:0007565| female pregnancy IDO1;EPN1 GO:0035556| intracellular signal transduction PLCD1;PLA2G1B GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;PLCD1;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0001525| angiogenesis CYP1B1;PLCD1;PTGS2 GO:0009791| post-embryonic development CYP1A2;ITPR1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8;ITPR1 GO:0070588| calcium ion transmembrane transport TRPM8;ITPR1;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G;CHRNA7;TRPV2;TRPV3;CACNA1H;OPRM1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;ITPKA;CACNA1I;PLCD1;ITPR1;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 GO:0065009| regulation of molecular function CYTH2;SPTBN1;TRPV1;ITPR1 GO:1900087| CYP1A1;RDX GO:0050796| regulation of insulin secretion ITPR1;CNR1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLCD1 GO:0001666| response to hypoxia CHRNA7;CAT;ITPR1;CYP1A1 GO:0010628| positive regulation of gene expression RDX;TRPV4 GO:0006644| phospholipid metabolic process PLCD1;PLA2G1B;NAPEPLD GO:0016042| lipid catabolic process NAPEPLD;PLCD1;DAGLA;PLA2G1B GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ITPR1;ABCC1;CACNA1G;TRPA1 GO:0006915| apoptotic process GPX1;ITPR1;VDAC1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;ITPR1;HTR2A 17793:[DB14011 DB00070] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00070|Hyaluronidase TGFB1;ALB common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;TGFB1 GO:0043117| positive regulation of vascular permeability TGFB1;TRPV4 GO:0048146| positive regulation of fibroblast proliferation TGFB1;PLA2G1B GO:0051781| positive regulation of cell division CAT;TGFB1 GO:0008285| negative regulation of cell proliferation TGFB1;OPRM1;PTGS2;PPARG;CYP1B1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;TGFB1 GO:0032930| positive regulation of superoxide anion generation TGFB1;SOD1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;TGFB1;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0033280| response to vitamin D PTGS2;TGFB1 GO:0008283| cell proliferation CYP1A1;GPX1;TGFB1;HTR1A GO:0001895| retina homeostasis ALB;SOD1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;TGFB1;PTGS2;CNR1;SOD1 GO:0042307| positive regulation of protein import into nucleus TGFB1;PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1;TGFB1 GO:0071260| cellular response to mechanical stimulus PTGS2;TGFB1 GO:0007507| heart development TGFB1;PPARG GO:0010575| positive regulation vascular endothelial growth factor production TGFB1;PTGS2;CYP1B1 GO:0000060| protein import into nucleus, translocation OPRD1;TGFB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;TGFB1;CAT GO:0006954| inflammatory response TGFB1;PTGS2;CNR2;PTGS1;ALOX5;IDO1;ALOX15;TRPV1 GO:0030217| T cell differentiation TGFB1;GPR18 GO:0048565| digestive tract development CYP1A1;TGFB1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;TGFB1 GO:0010629| negative regulation of gene expression OPRD1;TGFB1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;TGFB1 GO:0007565| female pregnancy IDO1;TGFB1 GO:0098869| GPX1;PTGS1;CAT;PTGS2;ALB;GSR GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TGFB1;TRPM8;TRPV4 GO:0031100| organ regeneration PPARG;TGFB1 GO:0009611| response to wounding CYP1A1;TGFB1;GPX1 GO:0032355| response to estradiol stimulus CAT;TGFB1;PTGS2;CYP1A2 GO:0071363| cellular response to growth factor stimulus OPRD1;TGFB1;CAT;TRPV1 GO:0007568| aging CYP1A1;CAT;PTGS2;TGFB1;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1 GO:0010468| regulation of gene expression TGFB1;CYP1A2 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;TGFB1 GO:0010628| positive regulation of gene expression TRPV4;TGFB1 GO:0001657| ureteric bud development CAT;TGFB1 GO:0010033| response to organic substance TGFB1;CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0042130| negative regulation of T cell proliferation IDO1;TGFB1 GO:0045892| negative regulation of transcription, DNA-dependent TGFB1;PPARG GO:0043406| positive regulation of MAP kinase activity TGFB1;HTR2A GO:0006915| apoptotic process GPX1;TGFB1;VDAC1 GO:0050714| positive regulation of protein secretion TGFB1;PLA2G1B GO:0060965| negative regulation of gene silencing by miRNA PPARG;TGFB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;TGFB1;HMGCR;GPR55;HTR2A GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;ALB GO:0045786| negative regulation of cell cycle TGFB1;PTGS2 GO:0002576| platelet degranulation SOD1;TGFB1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TGFB1;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;TGFB1;PTGS2 GO:0035307| positive regulation of protein dephosphorylation TGFB1;SMPD1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2;TGFB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TGFB1;PPARG;TRPV1;TRPV4 GO:0030308| negative regulation of cell growth TGFB1;PPARG GO:0042127| regulation of cell proliferation PTGS1;TGFB1;PTGS2 GO:0042060| wound healing TGFB1;OPRM1;ALOX15 GO:0010742| macrophage derived foam cell differentiation PPARG;TGFB1 GO:0051897| positive regulation of protein kinase B signaling cascade TGFB1;GPX1 GO:0071407| cellular response to organic cyclic compound TGFB1;CYP1A1;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent TGFB1;PPARG GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;TGFB1;SOD1;HTR2A;CAT 17794:[DB14011 DB00274] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;SLC15A2;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;CACNA1G;SLC15A1;TRPA1;GLRA1 GO:0001895| retina homeostasis ALB;SOD1 GO:0055085| transmembrane transport ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;SLC15A1;CACNA1G;ABCC1;TRPV2;SLC15A2;CACNA1H;TRPV3 GO:0006810| transport ABCG2;TRPV1;CACNA1I;SLC15A1;ABCC1;TRPV2;SLC15A2 GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;ALB GO:0002576| platelet degranulation SOD1;ALB 17795:[DB14011 DB02255] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02255|GM6001 ADAM28;ACAN common genes common pathways GO:0007155| cell adhesion ACAN;CYP1B1 GO:0007283| spermatogenesis ADAM28;SOD1;CNR1 17796:[DB14011 DB06468] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0042744| hydrogen peroxide catabolic process MPO;GPX1;CAT GO:0055085| transmembrane transport VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;SLC9A1;CACNA1H;TRPV3 GO:0007568| aging CYP1A1;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;MPO;CAT GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC9A1;SLC29A1 GO:0071468| cellular response to acidity TRPV1;SLC9A1 GO:0006979| response to oxidative stress PTGS2;SOD1;MPO;PTGS1;GPX1;CAT GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;MPO;GPX1;ALOX5;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19 GO:0071407| cellular response to organic cyclic compound SLC9A1;CYP1A1;CYP1B1 GO:0032094| response to food OPRM1;MPO;CYP1A1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MPO;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0043312| neutrophil degranulation ALOX5;MPO;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;MPO GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;MPO;GPX1;SLC9A1;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;PPARG;PLA2G1B GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;SLC9A1;ACAT1;AANAT;TRPA1;PPARG;CYP1A1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;SLC9A1;CHRNA7;CACNA1G;GLRA1;TRPA1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;SLC9A1 GO:0006812| cation transport TRPM8;SLC9A1 GO:0032869| cellular response to insulin stimulus SLC9A1;PPARG;PLA2G1B GO:0019430| removal of superoxide radicals SOD1;MPO GO:0071260| cellular response to mechanical stimulus PTGS2;SLC9A1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;SLC9A1 17797:[DB14011 DB07638] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A;ESR1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;ESR2;CACNA1I;PLA2G1B;ESR1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0006351| transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;ESR2;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG;ESR1 17798:[DB14011 DB06833] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways GO:0006351| transcription, DNA-dependent ESRRA;PPARG GO:0043401| steroid hormone mediated signaling pathway ESRRA;PPARG GO:0042127| regulation of cell proliferation ESRRA;PTGS2;PTGS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRA;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESRRA;TRPV4;TRPV1 GO:0006355| regulation of transcription, DNA-dependent ESRRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESRRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESRRA GO:0032355| response to estradiol stimulus ESRRA;CAT;CYP1A2;PTGS2 17799:[DB14011 DB13932] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13932|Voretigene Neparvovec RPE65 common genes common pathways GO:0007623| circadian rhythm AANAT;RPE65 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;PTGS1;GPX1;RPE65;CRYZ;CYP1A1;CYP2C9;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0042574| retinal metabolic process CYP1B1;RPE65 GO:0009416| response to light stimulus AANAT;RPE65 GO:0042572| retinol metabolic process CYP1B1;RPE65 GO:0043010| camera-type eye development CYP1A1;RPE65 GO:0007601| visual perception GLRB;CYP1B1;GLRA1;CRYZ;RPE65 GO:0001523| retinoid metabolic process RPE65;NAPEPLD GO:0050896| response to stimulus TRPA1;TRPM8;RPE65 GO:0001895| retina homeostasis RPE65;SOD1 17800:[DB14011 DB07967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07967|9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE CTSK common genes common pathways GO:1903146| VDAC1;CTSK GO:0045453| bone resorption GPR55;CTSK 17801:[DB14011 DB06358] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06358|Iclaprim DHFR common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;DHFR;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 17802:[DB14011 DB02306] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 17803:[DB14011 DB09276] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09276|Sodium aurothiomalate UGT1A1 common genes common pathways GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;UGT1A1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1;UGT1A1 GO:0042594| response to starvation ACAT1;UGT1A1;PPARG GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1;UGT1A1 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;UGT1A1;CYP1A1;CYP2C9;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C19;UGT1A1;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1;ACAT1 GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;UGT1A1;CYP1A1;CYP1A2;CYP3A4 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0008152| metabolic process SMPD1;UGT1A1;ACAT1 GO:0014070| response to organic cyclic compound UGT1A1;TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;ACAT1;AANAT GO:0007584| response to nutrient UGT1A1;PPARG;HMGCR;CNR1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H 17804:[DB14011 DB00689] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00689|Cephaloglycin SLC22A5 common genes common pathways GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLC22A5;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A5 GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;SLC22A5;GLRA3 17805:[DB14011 DB08089] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08089|LGD-2226 AR common genes common pathways GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis SOD1;CNR1;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;AR;TRPV2 GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation AR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV4;TRPV1 GO:0008283| cell proliferation GPX1;AR;HTR1A;CYP1A1 GO:0007548| sex differentiation AR;CYP17A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;OPRM1;PTGS2 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;AR;CHRNA7 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006351| transcription, DNA-dependent PPARG;AR 17806:[DB14011 DB01044] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes CYP1A2 common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0001895| retina homeostasis SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;IDO1;CYP1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0098869| ALB;GSR;CAT;GPX1;PTGS1;PTGS2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;PTGS2;CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 17807:[DB14011 DB04012] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport CACNA1I;TRPV4;TRPV1;TRPM8;FKBP1A;CACNA1G;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;FKBP1A;TRPV1 GO:0006936| muscle contraction GLRA1;FKBP1A;CACNA1H GO:0031000| response to caffeine FKBP1A;PPARG GO:1902991| FKBP1A;CHRNA7 17808:[DB14011 DB02557] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02557|Phosphoramidon MME;KEL common genes common pathways GO:0042310| vasoconstriction HTR1A;KEL GO:0019233| sensory perception of pain OPRD1;PTGS2;CNR2;MME;OPRM1;CNR1;HTR2A;TRPA1;TRPV1 GO:0071345| cellular response to cytokine stimulus MME;TRPV1 GO:0043312| neutrophil degranulation MME;ALOX5;CAT GO:0001822| kidney development CAT;MME GO:0006874| cellular calcium ion homeostasis CHRNA7;KEL;GPR12;HTR2A;TRPM8;TRPV4 GO:0048741| skeletal muscle fiber development GPX1;KEL 17809:[DB14011 DB04281] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0031000| response to caffeine PPARG;DHODH GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0042493| response to drug ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;CAT;DHODH;PTGS2;CYP1A2;SOD1;HTR2A GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;DHODH;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0014070| response to organic cyclic compound DHODH;ACAT1;AANAT;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;DHODH;SOD1;CNR1;PTGS2 GO:0007565| female pregnancy DHODH;IDO1 GO:0007595| lactation SLC29A1;DHODH 17810:[DB14011 DB05171] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05171|E-2012 APH1A;PSENEN common genes common pathways GO:0043065| positive regulation of apoptotic process PSENEN;CNR1;SOD1;PTGS2;APH1A;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0043085| positive regulation of catalytic activity PSENEN;SOD1;APH1A 17811:[DB14011 DB03332] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03332|5,6-Cyclic-Tetrahydropteridine NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;NOS3;CYP1B1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0042311| vasodilation GPX1;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development CYP1A2;NOS3 GO:0045766| positive regulation of angiogenesis CYP1B1;NOS3;CHRNA7 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat NOS3;TRPV1;TRPV2;SOD1;TRPV3 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CYP1B1;PPARG;OPRM1;PTGS2 GO:0008217| regulation of blood pressure NOS3;PPARG;PTGS1;SOD1;PTGS2 GO:1902042| NOS3;GPX1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0045454| cell redox homeostasis GPX1;GSR;NOS3 17812:[DB14011 DB00772] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes CYP1A2 common pathways GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2B6;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP1A1;CYP2C9;CYP2B6;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;BCHE;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;PTGS1;ALOX5;GPX1;CYP2B6;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;BCHE;CYP1B1 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2B6;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;PTGS1;NAAA;GPX1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2B6;CYP2C9;CYP2C19 17813:[DB14011 DB03760] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03760|Dihydrolipoic Acid GCSH;DLAT;PDK3 common genes common pathways GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;PDK3 GO:0030431| sleep HTR2A;SLC29A1;DLAT;CACNA1I GO:0008152| metabolic process ACAT1;SMPD1;DLAT GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;PDK3 GO:0071333| cellular response to glucose stimulus SLC29A1;PDK3 GO:0032259| methylation GCSH;CYP1A2 17814:[DB14011 DB07135] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 17815:[DB14011 DB07525] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways GO:0007420| brain development FGFR1;ACAT1 GO:0010976| positive regulation of neuron projection development FGFR1;CNR1 GO:0010629| negative regulation of gene expression FGFR1;OPRD1 GO:0048469| cell maturation FGFR1;PPARG GO:0001525| angiogenesis FGFR1;PTGS2;CYP1B1 GO:0006351| transcription, DNA-dependent FGFR1;PPARG GO:0001657| ureteric bud development FGFR1;CAT GO:0043406| positive regulation of MAP kinase activity FGFR1;HTR2A GO:0007605| sensory perception of sound GPX1;SOD1;FGFR1 GO:0010468| regulation of gene expression CYP1A2;FGFR1 GO:0048514| blood vessel morphogenesis CYP1B1;FGFR1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FGFR1;CAT GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGFR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;FGFR1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;FGFR1;HTR2A;PTGS2;HMGCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;FGFR1 GO:0042127| regulation of cell proliferation PTGS2;FGFR1;PTGS1 GO:0030324| lung development FGFR1;CYP1A2 17816:[DB14011 DB06993] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A 17817:[DB14011 DB05667] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05667|Levoketoconazole CYP11B1;CYP51A1 common genes common pathways GO:0070988| demethylation CYP1A1;CYP51A1 GO:0006629| lipid metabolic process CYP1A2;CYP51A1;PTGS2;HMGCR;CYP11B1;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP11B1;CYP51A1 GO:0016126| sterol biosynthetic process CYP51A1;HMGCR GO:0006955| immune response CNR2;CYP11B1;OPRD1 GO:0034651| cortisol biosynthetic process CYP11B1;CACNA1H GO:0032870| cellular response to hormone stimulus CACNA1H;CYP11B1 GO:0035865| cellular response to potassium ion SOD1;CACNA1H;CYP11B1 GO:0008217| regulation of blood pressure PTGS1;CYP11B1;PTGS2;SOD1;PPARG GO:0006695| cholesterol biosynthetic process CYP51A1;HMGCR GO:0008203| cholesterol metabolic process CAT;CYP51A1;HMGCR GO:0032342| aldosterone biosynthetic process CYP11B1;CACNA1H GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP11B1;CYP1A2;PTGS2;CYP3A7;CYP51A1;SOD1;CYP3A4;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0006694| steroid biosynthetic process CYP51A1;HMGCR;CYP11B1;CYP17A1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP51A1;CYP3A7;CYP1A2;CYP11B1;HMGCR;CYP3A4 GO:0006704| glucocorticoid biosynthetic process CYP17A1;CYP11B1 GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1;CYP11B1 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;CYP51A1 17818:[DB14011 DB06184] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06184|AEG35156 XIAP common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;XIAP;GPX1 GO:0050727| regulation of inflammatory response XIAP;PTGS2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;XIAP GO:0042127| regulation of cell proliferation PTGS1;XIAP;PTGS2 GO:0006915| apoptotic process GPX1;XIAP;VDAC1 17819:[DB14011 DB02919] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP1A1;CYP2C9;DHFR;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR 17820:[DB14011 DB07141] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;DHFR;CRYZ;CYP2C9;CYP1A1;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 17821:[DB14011 DB00421] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes CACNA1I;CACNA1G;CACNA1H common pathways GO:0007565| female pregnancy IDO1;ABCC2 GO:0008209| androgen metabolic process SRD5A2;CYP3A4;SRD5A1 GO:0031667| response to nutrient levels SOD1;SRD5A2 GO:0071320| cellular response to cAMP SRD5A1;AANAT GO:0098703| TRPV1;CACNA2D1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C8;CYP2C9;NR1I2 GO:0010629| negative regulation of gene expression OPRD1;PGR GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;CACNA1B;GLRA3;CACNB2;CACNB4;CACNA1G;GLRA1;CACNB3;GLRB;VDAC1;CACNB1 GO:0086010| CACNA1H;CACNA1B;CACNA1F;CACNA1I;CACNA1A;CACNA1S;CACNA1G GO:0051924| regulation of calcium ion transport CACNA1B;CACNA2D1;OPRD1 GO:0006955| immune response OPRD1;CYP11B1;CNR2 GO:0042448| progesterone metabolic process SRD5A1;SRD5A2;CYP17A1 GO:0006816| calcium ion transport CHRNA7;CACNG1;CACNA1D;CACNB4;TRPV2;CACNA1C;CACNA2D1;CACNB2;CACNA1B;CACNA1H;TRPV3;CACNB1;CACNA2D3;TRPM8;CACNA1A;CACNA1I;TRPV4;TRPV1;CACNA1F;CACNA2D2;TRPA1;CACNB3;CACNA1G;CACNA1S GO:0034651| cortisol biosynthetic process CYP11B1;CYP11B2;CACNA1H GO:0009408| response to heat SOD1;TRPV3;TRPV2;ABCC2;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0001889| liver development CYP1A1;ACAT1;SRD5A1 GO:0006351| transcription, DNA-dependent NR3C1;AR;PPARG;NR1I2;NR3C2;PGR GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1G;CACNA1I GO:0030431| sleep SLC29A1;HTR2A;CACNA1I GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;ABCB11 GO:0043401| steroid hormone mediated signaling pathway NR3C1;AR;NR1I2;PPARG;NR3C2;PGR GO:0098662| CACNA1H GO:0086091| CACNA1G;CACNA1D;CACNA1C;CACNB2;CACNA2D1 GO:0008016| regulation of heart contraction CACNA1H;CACNA1B GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0006706| steroid catabolic process CYP3A4;SRD5A2;CYP1A2 GO:0006629| lipid metabolic process SRD5A1;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;SRD5A2;SRD5A3;CYP1A2;PTGS2;HMGCR;CYP11B2;CYP11B1;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0002027| regulation of heart rate CACNA1G GO:0007507| heart development CACNA1C;PPARG GO:0042428| serotonin metabolic process HTR1A;SRD5A1 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP11B2;CYP11B1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP1B1;CYP2C9;NR1I2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CACNA1D GO:0007548| sex differentiation SRD5A1;AR;SRD5A2;CYP17A1 GO:0006702| androgen biosynthetic process CYP17A1;SRD5A3;SRD5A2;SRD5A1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2;ABCC2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;SRD5A2;CYP1A2;PTGS2;SRD5A1;AANAT;ACAT1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;AR GO:0086045| CACNA1G;CACNB2;CACNA1C GO:0006811| ion transport CACNA1G;CACNA1S;CACNA2D2;CACNB3;GLRA1;TRPA1;TRPV1;CACNA1A;VDAC1;CACNA1I;TRPV4;GLRB;CACNA1F;CACNB1;TRPM8;CACNA2D3;CACNA1H;SLCO1A2;TRPV3;CACNA2D1;CACNB2;GLRA3;CACNA1B;CACNB4;TRPV2;CACNA1D;CACNA1C;CHRNA7;CACNG1 GO:0008217| regulation of blood pressure PPARG;SOD1;CACNA1B;PTGS2;CYP11B1;PTGS1 GO:0035865| cellular response to potassium ion SOD1;CYP11B1;CYP11B2;CACNA1H GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;AR GO:0086046| CACNA1G;CACNA1D GO:0043627| response to estrogen stimulus SRD5A1;ABCC2;PPARG GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G GO:0050896| response to stimulus TRPA1;CACNA1F;TRPM8 GO:0007601| visual perception CACNB2;GLRB;CYP1B1;CACNA1F;GLRA1;CRYZ GO:0042908| xenobiotic transport NR1I2;ABCC1;ABCG2;ABCB1 GO:0050796| regulation of insulin secretion CACNA1C;CACNA1D;CNR1;CACNA1A;CACNA2D2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;CACNA1A;TRPV1;HTR2A;OPRM1;CACNA1C GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;SRD5A1 GO:0007520| myoblast fusion CACNA1H GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0043434| response to peptide hormone stimulus SRD5A2;TRPV1 GO:0040014| regulation of multicellular organism growth SOD1;CACNA2D2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:2000344| positive regulation of acrosome reaction GLRA1;CACNA1H GO:0097267| CYP1A2;CYP2C19;CYP2C8;CYP1B1;CYP2C9;CYP1A1 GO:0007165| signal transduction SMPD1;GPR18;NR1I2;PPARG;PLA2G1B;PGR;CACNA1I;NR3C2;NR3C1;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;AR GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CACNA1G;CACNA1I GO:1904645| CACNA1A;CHRNA7 GO:0043010| camera-type eye development CYP1A1;CACNA1C GO:0032870| cellular response to hormone stimulus CACNA1H;CYP11B2;CYP11B1;ABCC2 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C8;CYP2C9;CYP3A4;CYP1A2 GO:0070588| calcium ion transmembrane transport CACNA2D2;TRPA1;CACNB3;CACNA1G;CACNA1S;CACNB1;TRPM8;CACNA2D3;TRPV1;CACNA1A;TRPV4;CACNA1I;CACNA1F;CACNA2D1;CACNB2;CACNA1B;CACNA1H;OPRM1;TRPV3;CHRNA7;CACNG1;CACNB4;TRPV2;CACNA1D;CACNA1C GO:0034765| regulation of ion transmembrane transport CACNB3;CACNA2D2;CACNA1S;CACNA1G;CACNB1;CACNA2D3;CACNA1I;CACNA1A;CACNA1F;CACNB2;CACNA2D1;CACNA1B;CACNA1H;CACNG1;CACNB4;CACNA1D;CACNA1C GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C8;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP11B2;CYP11B1;CYP3A4;SOD1;SRD5A2;SRD5A3;PTGS1;ALOX5;GPX1;SRD5A1;CAT GO:0032342| aldosterone biosynthetic process CYP11B1;CYP11B2;CACNA1H GO:0022900| electron transport chain CYP1A2;SRD5A1;GSR;IDO1 GO:0099133| ABCC2;ABCC1 GO:0007517| muscle organ development CACNA1H GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG;AR GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;SRD5A1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;AR;PPARG;NR1I2;PGR;NR3C2 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0042493| response to drug CAT;SRD5A1;PTGS2;CYP1A2;SRD5A2;HTR2A;SOD1;ABCB1;ABCC2;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0048265| response to pain TRPA1;TRPV1;CACNA1B GO:0006367| transcription initiation from RNA polymerase II promoter PGR;NR3C2;NR1I2;PPARG;AR;NR3C1 GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;CYP11B2;CYP11B1;SRD5A2;SRD5A1 GO:0030317| sperm motility CACNA1I GO:0007269| neurotransmitter secretion NAAA;CACNA1B GO:0070509| calcium ion import CACNA1I;TRPV4;CACNA1G;CACNA1D;CACNB2;CACNA1H GO:0086016| CACNA1G GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2;SRD5A2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;IDO1;ABCC2 GO:0001508| regulation of action potential CACNA1G;GLRA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;NR3C1;AR GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C8;CYP1A1;CYP2C9 GO:0086015| CACNA1G GO:0010045| response to nickel cation CACNA1G GO:0007626| locomotory behavior SOD1;CACNA1B;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;AR;PPARG;NR1I2;PLA2G1B;PGR GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;AR GO:0008219| cell death CACNA1A;HTR2A GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0086002| CACNA1C;CACNA1D;CACNA2D1;CACNA1G GO:0055085| transmembrane transport ABCC2;TRPM8;ABCG2;CACNA1F;TRPV1;CACNA1A;VDAC1;CACNA1I;ABCB1;TRPV4;TRPA1;ABCC1;CACNA1G;CACNA1S;CACNA1C;TRPV2;CACNA1D;ABCB11;CACNA1B;SLCO1A2;TRPV3;CACNA1H GO:0002933| CYP3A5;CYP2C8;CYP1A1;CYP3A4;CYP3A7 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1;SRD5A2 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0007283| spermatogenesis AR;SOD1;CNR1 GO:0010628| positive regulation of gene expression AR;TRPV4;NR1I2 GO:0006810| transport ABCC1;CACNB3;ABCB1;CACNA1I;TRPV1;ABCC2;CACNB1;ABCG2;ABCB11;CACNA1B;CACNB4;TRPV2;CACNG1;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0008202| steroid metabolic process NR1I2;CYP2C9;CYP1A1;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP17A1;CYP1B1;SRD5A2;CYP3A4;HMGCR;CYP11B2;CYP11B1;CYP1A2;CYP3A7;SRD5A1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;SRD5A1;TRPV1 GO:0086027| CACNA1G GO:0086018| CACNA1G GO:0032355| response to estradiol stimulus SRD5A1;CAT;CYP1A2;PTGS2 GO:0006704| glucocorticoid biosynthetic process CYP11B1;CYP17A1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4 GO:0007605| sensory perception of sound GPX1;CACNA1D;SOD1 GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;CACNA1H GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;ABCC2 GO:0006936| muscle contraction CACNG1;CACNA1H;GLRA1;CACNA1S GO:0042593| glucose homeostasis CYP11B1;CNR1;TRPV4;PPARG 17822:[DB14011 DB05078] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05078|AER001 IL4R;IL13RA2 common genes common pathways GO:0043627| response to estrogen stimulus IL4R;PPARG GO:0007165| signal transduction IL13RA2;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;IL4R;HTR1A;GPR55;CHRNA7 GO:0006955| immune response OPRD1;CNR2;IL4R GO:0030728| ovulation IL4R;PTGS2 GO:0002376| immune system process IL4R;IDO1 GO:0042127| regulation of cell proliferation PTGS1;IL4R;PTGS2 17823:[DB14011 DB05332] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05332|Romiplostim MPL common genes common pathways GO:0008283| cell proliferation MPL;HTR1A;GPX1;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;MPL 17824:[DB14011 DB05339] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05339|MN-305 HTR1A common genes HTR1A common pathways GO:0035640| exploration behavior HTR1A GO:0050795| regulation of behavior HTR2A;HTR1A GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0014062| regulation of serotonin secretion HTR1A GO:0007210| serotonin receptor signaling pathway HTR2A;HTR1A GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18 GO:0042310| vasoconstriction HTR1A GO:0042428| serotonin metabolic process HTR1A GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0001662| behavioral fear response HTR1A;VDAC1 GO:0042053| regulation of dopamine metabolic process HTR1A GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0007610| behavior HTR2A;HTR1A 17825:[DB14011 DB07036] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;ESR2;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR2 GO:0006351| transcription, DNA-dependent ESR2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR2;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;ESR2;PPARG GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG 17826:[DB14011 DB00415] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;TEK;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CHRNA7 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0043434| response to peptide hormone stimulus TRPV1;TEK GO:0043627| response to estrogen stimulus PPARG;TEK GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A5 GO:0001895| retina homeostasis ALB;SOD1 GO:0006811| ion transport SLC22A5;SLC15A2;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;SLC15A1;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB GO:0007507| heart development PPARG;TEK GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;SLC16A1;PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0035556| intracellular signal transduction TEK;PLA2G1B GO:0001525| angiogenesis CYP1B1;TEK;PTGS2 GO:0001934| positive regulation of protein phosphorylation TEK;CHRNA7 GO:0042593| glucose homeostasis TRPV4;PPARG;SLC16A1;CNR1 GO:0098869| GSR;ALB;PTGS2;PTGS1;GPX1;CAT GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade TEK;CAT GO:0006810| transport ABCC1;SLC15A1;CACNA1I;TRPV1;ABCG2;SLC15A2;TRPV2 GO:0010033| response to organic substance TEK;PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;TEK GO:0055085| transmembrane transport SLC16A1;TRPV2;SLC22A5;SLC15A2;CACNA1H;TRPV3;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;SLC15A1;CACNA1G;ABCC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;TEK;ALOX15 GO:0045766| positive regulation of angiogenesis CHRNA7;TEK;CYP1B1 GO:0051591| response to cAMP AANAT;TEK GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process ALB;TEK;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0051897| positive regulation of protein kinase B signaling cascade TEK;GPX1 GO:0016525| negative regulation of angiogenesis PPARG;TEK GO:0050728| negative regulation of inflammatory response CNR2;TEK GO:0032094| response to food OPRM1;SLC16A1;CYP1A1 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1B1;CYP1A1 17827:[DB14011 DB00110] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction VDAC1;FCGR2B;HTR2A GO:0006955| immune response C1R;FCGR2B;FCGR3B;FCGR1A;FCGR3A;OPRD1;FCGR2C;CNR2;C1QC GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;FCGR2B;PTGS1;ALOX5;CNR2;PTGS2 GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0007165| signal transduction CHRNA7;FCGR2C;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;PLA2G1B;CACNA1I;FCGR1A;SMPD1;GPR18;PPARG;FCGR2B GO:0043312| neutrophil degranulation FCGR2A;FCGR3B;ALOX5;CAT GO:0045087| innate immune response C1QA;C1QC;FCGR1A;PPARG;C1QB;C1R GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0002376| immune system process IDO1;FCGR1A;FCGR2A;C1R;C1QB;C1QA;C1QC 17828:[DB14011 DB03084] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03084|Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine MAPK10 common genes common pathways GO:0010468| regulation of gene expression MAPK10;CYP1A2 GO:0000187| activation of MAPK activity CHRNA7;SOD1;MAPK10;PLA2G1B GO:0048511| rhythmic process MAPK10;PPARG;AANAT GO:0009416| response to light stimulus AANAT;MAPK10 GO:0042752| regulation of circadian rhythm MAPK10;PPARG GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;MAPK10;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7 17829:[DB14011 DB01094] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes CYP1A2;ABCG2 common pathways GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0008203| cholesterol metabolic process HMGCR;SOAT1;CAT;SOAT2 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0033344| cholesterol efflux ABCG2;SOAT2;SOAT1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP2C9;CYP1A1;CRYZ;ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0010742| macrophage derived foam cell differentiation PPARG;SOAT1;SOAT2 GO:0015886| heme transport ABCG2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;SOAT2;CYP1A2;CYP3A7;SOAT1;HMGCR;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;TRPV2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;MTTP;ALOX15;DAGLA;CYP2D6;CYP1A2;SOAT1;PTGS2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;SOAT2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0046415| urate metabolic process ABCG2 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;ACAT1;AANAT GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 17830:[DB14011 DB05139] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05139|CR002 PDGFD common genes common pathways GO:0070301| cellular response to hydrogen peroxide PDGFD;CYP1B1 GO:0051781| positive regulation of cell division CAT;PDGFD GO:0048146| positive regulation of fibroblast proliferation PDGFD;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;PDGFD;GPR55 GO:0043406| positive regulation of MAP kinase activity HTR2A;PDGFD GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PDGFD GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;PDGFD GO:0071230| cellular response to amino acid stimulus GLRA1;PDGFD GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;PDGFD;CHRNA7 17831:[DB14011 DB11275] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0008284| positive regulation of cell proliferation DRD3;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;DRD3;PPARG GO:0007626| locomotory behavior DRD2;DRD3;DRD1;OPRM1;SOD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD5;DRD1;DRD3 GO:0042311| vasodilation GPX1;DRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;DRD3;PPARG GO:0007628| adult walking behavior DRD1;DRD2;GLRB;GLRA1 GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0007612| learning DRD1;DRD5;PTGS2;VDAC1;DRD3 GO:0042060| wound healing ALOX15;OPRM1;DRD5 GO:0007611| learning or memory DRD3;CHRNA7;CNR1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;DRD2;GLRB;GLRA1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0043278| response to morphine CNR1;OPRM1;DRD2;DRD3 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0035094| response to nicotine CNR1;CHRNA7;DRD2 GO:0042493| response to drug DRD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;DRD2;DRD3;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0006936| muscle contraction GLRA1;CACNA1H;DRD1 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;DRD4;CHRNA7;DRD5;DRD3;TRPM8;DRD2;TRPV4 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;DRD2;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;DRD4;GPR55;HTR1A;HTR2A;GPR12;CNR1;DRD5;DRD1;PPARG;GPR18;DRD3;DRD2 GO:0001666| response to hypoxia CHRNA7;CAT;DRD2;CYP1A1 GO:0010628| positive regulation of gene expression DRD1;TRPV4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;CNR2;OPRM1;OPRD1;CNR1 GO:0009416| response to light stimulus DRD2;AANAT GO:0048511| rhythmic process DRD4;AANAT;PPARG GO:0014059| regulation of dopamine secretion HTR2A;DRD2;DRD3 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD2;GPR18;DRD1;GPR55 GO:0060080| regulation of inhibitory postsynaptic membrane potential DRD4;GLRA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;DRD2;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0042220| response to cocaine SMPD1;DRD3;DRD2;OPRM1;CNR1;DRD5;DRD1 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1;DRD4 GO:0001659| temperature homeostasis TRPV1;DRD2;GPX1;DRD1;HTR2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0035556| intracellular signal transduction PLA2G1B;DRD2 GO:0048148| behavioral response to cocaine DRD1;HTR2A;DRD4;DRD2;DRD3 GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;DRD2;DRD3 GO:0045776| negative regulation of blood pressure DRD2;DRD3;DRD5;CNR1 GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;DRD1;CACNA1H GO:0048678| response to axon injury SOD1;DRD2 GO:0019226| transmission of nerve impulse SOD1;DRD1;DRD5 GO:0001964| startle response GLRB;DRD2;GLRA1 GO:0033674| positive regulation of kinase activity DRD4;HTR2A GO:0042752| regulation of circadian rhythm DRD4;PPARG GO:0008542| visual learning HMGCR;DRD1;DRD3;DRD2 GO:0007268| synaptic transmission DRD5;OPRM1;OPRD1;GLRA3;HTR2A;GLRB;VDAC1;CACNA1G;GLRA1 GO:0048149| behavioral response to ethanol OPRM1;DRD4;DRD2 GO:1900273| CHRNA7;DRD2 GO:0050482| arachidonic acid secretion DRD4;DRD3;PLA2G1B;DRD2 GO:0007165| signal transduction SMPD1;GPR18;DRD3;PPARG;PLA2G1B;CACNA1I;DRD2;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;DRD4;DRD5;DRD1;CHRNA7 GO:0072593| reactive oxygen species metabolic process SOD1;DRD5 GO:0040014| regulation of multicellular organism growth SOD1;DRD3 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;DRD3;PPARG;CYP1A1 GO:0001975| response to amphetamine DRD4;SOD1;CNR2;DRD1;DRD5;DRD3;DRD2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7;DRD1 GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0042053| regulation of dopamine metabolic process HTR1A;DRD4;DRD1 GO:0001662| behavioral fear response DRD1;DRD4;HTR1A;VDAC1 GO:0008285| negative regulation of cell proliferation PPARG;DRD2;CYP1B1;PTGS2;OPRM1 GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0009636| response to toxin CYP1A1;DRD2;CYP1B1;CAT;GPX1 GO:0014854| response to inactivity DRD2;CAT GO:0008344| adult locomotory behavior OPRD1;DRD4 17832:[DB14011 DB00650] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC22A8;TRPV2;ABCC1;CACNA1G;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;SLC22A8;TRPV2;CHRNA7 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC22A8 GO:0098656| SLC22A8;VDAC1 17833:[DB14011 DB09026] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09026|Aliskiren REN;CYP3A4 common genes CYP3A4 common pathways GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;NAAA;GPX1;PTGS1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 GO:0048469| cell maturation REN;PPARG GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;REN;PPARG GO:0035902| response to immobilization stress CYP1A2;REN;CYP1A1;PPARG GO:0001822| kidney development CAT;REN GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;IDO1;CYP1A1;REN GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;REN;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0010033| response to organic substance PPARG;CYP1A1;REN;TRPA1;CYP1A2;PTGS2;SOD1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0051591| response to cAMP AANAT;REN 17834:[DB14011 DB07028] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07028|(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;AKR1B1;CYP1A1;PPARG;TRPA1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;AKR1B1 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;AKR1B1;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 17835:[DB14011 DB04738] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04738|Motuporin PPP1CC common genes common pathways GO:0042752| regulation of circadian rhythm PPARG;PPP1CC GO:0048511| rhythmic process PPP1CC;PPARG;AANAT 17836:[DB14011 DB04444] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04444|Tetrafluoroaluminate Ion argB;GNAI1;ATP2A1;GNAT1;CMPK1;MYH11;MYH14;recA;rbsK common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GNAI1;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;GNAT1 GO:0007605| sensory perception of sound MYH14;GPX1;SOD1 GO:0006936| muscle contraction MYH11;GLRA1;CACNA1H GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;ATP2A1;GLRB;TRPV1 GO:0009416| response to light stimulus AANAT;GNAT1 GO:0070509| calcium ion import CACNA1G;ATP2A1;CACNA1I;TRPV4;CACNA1H GO:0009642| response to light intensity CAT;GNAT1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;GNAI1 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB;GNAT1 GO:0043434| response to peptide hormone stimulus TRPV1;GNAI1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;GNAT1;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;GNAI1;SMPD1;CACNA1I;PLA2G1B GO:0006939| smooth muscle contraction MYH11;HTR2A GO:0070588| calcium ion transmembrane transport TRPV3;CACNA1H;OPRM1;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV4;CACNA1I;TRPV1;ATP2A1;TRPM8 GO:0015949| nucleobase-containing small molecule interconversion GSR;CMPK1 GO:0006139| nucleobase-containing compound metabolic process CMPK1;SLC29A1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;ATP2A1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0008283| cell proliferation CYP1A1;GPX1;GNAT1;HTR1A GO:0034976| response to endoplasmic reticulum stress ATP2A1;ALOX15 GO:0050896| response to stimulus GNAT1;TRPM8;TRPA1 GO:0019228| regulation of action potential in neuron CACNA1I;MYH14;CACNA1G;CACNA1H GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger GNAI1;GNAT1;CNR1 GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;ATP2A1;CACNA1I;TRPV4;TRPV1 17837:[DB14011 DB08449] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08449|2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid AKR1B1 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1;AKR1B1 GO:0022900| electron transport chain AKR1B1;GSR;IDO1;CYP1A2 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process CRYZ;AKR1B1;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0043066| negative regulation of apoptotic process AKR1B1;SOD1;PTGS2;HMGCR;CAT;GPX1 17838:[DB14011 DB07542] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07542|5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOBUTYL-HEXANOIC ACID CTSD common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;CTSD 17839:[DB14011 DB05001] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05001|PSN9301 DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 17840:[DB14011 DB11973] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11973|Tesevatinib EGF;EPHB4;ERBB2 common genes common pathways GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;EGF;HTR1A;CHRNA7 GO:0002576| platelet degranulation SOD1;EGF GO:0007155| cell adhesion EPHB4;CYP1B1 GO:0042060| wound healing ALOX15;OPRM1;ERBB2 GO:0051897| positive regulation of protein kinase B signaling cascade EGF;GPX1;ERBB2 GO:0045893| positive regulation of transcription, DNA-dependent EGF;PPARG GO:0006355| regulation of transcription, DNA-dependent ERBB2;PPARG GO:0043388| positive regulation of DNA binding PPARG;EGF GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;ERBB2;OPRD1 GO:0010628| positive regulation of gene expression TRPV4;EGF;ERBB2 GO:0043406| positive regulation of MAP kinase activity HTR2A;EGF;ERBB2 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;EGF;SOD1 GO:0007399| nervous system development ERBB2;SMPD1;GLRB GO:0007507| heart development PPARG;ERBB2 GO:0006357| regulation of transcription from RNA polymerase II promoter ERBB2;PPARG GO:0006351| transcription, DNA-dependent ERBB2;PPARG GO:0001525| angiogenesis EPHB4;CYP1B1;EGF;PTGS2 GO:0007166| cell surface receptor linked signaling pathway ERBB2;TRPA1;TRPV1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation EGF;HTR2A GO:0001934| positive regulation of protein phosphorylation ERBB2;CHRNA7 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;ERBB2 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;CNR1;GPR12;HTR2A;HTR1A;EGF;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;ERBB2 GO:0008283| cell proliferation CYP1A1;GPX1;ERBB2;HTR1A 17841:[DB14011 DB00111] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0002376| immune system process C1QA;IL2RA;C1QC;IDO1;FCGR2A;FCGR1A;C1R;C1QB GO:0042130| negative regulation of T cell proliferation IL2RA;IDO1 GO:0006915| apoptotic process VDAC1;GPX1;IL2RA GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;IL2RB GO:0045087| innate immune response C1QC;C1QA;C1R;C1QB;PPARG;FCGR1A GO:0043312| neutrophil degranulation FCGR3B;FCGR2A;ALOX5;CAT GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0050728| negative regulation of inflammatory response CNR2;IL2RA GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;FCGR2C;FCGR1A;CACNA1I;PLA2G1B;FCGR2B;PPARG;GPR18;IL2RB;SMPD1 GO:0065009| regulation of molecular function IL2RA;IL2RB;TRPV1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;IL2RA GO:0007166| cell surface receptor linked signaling pathway IL2RA;TRPA1;TRPV1 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;IL2RA;TRPV1;IDO1;ALOX15;FCGR2B GO:0016032| viral reproduction VDAC1;IL2RB;FCGR2B;HTR2A GO:0006955| immune response CNR2;IL2RA;FCGR3A;FCGR2C;OPRD1;C1QC;FCGR1A;C1R;FCGR3B;FCGR2B GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 17842:[DB14011 DB06857] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06857|N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE PLAU common genes common pathways GO:0001666| response to hypoxia CYP1A1;PLAU;CAT;CHRNA7 GO:0043312| neutrophil degranulation CAT;ALOX5;PLAU GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0007165| signal transduction GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLAU;PLA2G1B;CACNA1I 17843:[DB14011 DB13933] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0009725| response to hormone stimulus ACAT1;F7 GO:0043627| response to estrogen stimulus F7;PPARG GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;F7;PTGS2;CYP1A2;ACAT1;AANAT GO:0031667| response to nutrient levels SOD1;F7 GO:0031100| organ regeneration F7;PPARG GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;F7 GO:0001666| response to hypoxia CYP1A1;F7;CHRNA7;CAT GO:0002576| platelet degranulation SOD1;F8 GO:0007623| circadian rhythm AANAT;F7 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10;F7 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1;F8;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 17844:[DB14011 DB07325] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07325|N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE HSP90AA1 common genes common pathways GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;SOD1;TRPV3 GO:0009409| response to cold TRPA1;PPARG;HSP90AA1;TRPM8 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;HSP90AA1;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HSP90AA1 17845:[DB14011 DB04796] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04796|Inecalcitol VDR common genes common pathways GO:0006816| calcium ion transport CHRNA7;VDR;TRPV2;TRPV3;CACNA1H;TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G GO:0007595| lactation VDR;SLC29A1 GO:0006351| transcription, DNA-dependent PPARG;VDR GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;VDR GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;VDR;CHRNA7 GO:0006367| transcription initiation from RNA polymerase II promoter VDR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;VDR GO:0010628| positive regulation of gene expression TRPV4;VDR GO:0045892| negative regulation of transcription, DNA-dependent PPARG;VDR GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;GPR12;HTR2A;VDR;CHRNA7 GO:0046697| decidualization PTGS2;VDR 17846:[DB14011 DB02930] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02930|Adenosine 5'-[γ-thio]triphosphate BST1;SYN1;BCKDK;PFKFB1;PMS2;recA;recA;recA;recQ common genes common pathways GO:0007269| neurotransmitter secretion NAAA;SYN1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;BST1 GO:0042594| response to starvation PFKFB1;ACAT1;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;BST1 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;PMS2;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0009083| branched chain family amino acid catabolic process BCKDK;ACAT1 GO:0031100| organ regeneration PFKFB1;PPARG GO:0051591| response to cAMP PFKFB1;AANAT GO:0045821| positive regulation of glycolysis HTR2A;PFKFB1 GO:0050727| regulation of inflammatory response BST1;PTGS2 GO:0008152| metabolic process ACAT1;PFKFB1;SMPD1 GO:0007268| synaptic transmission SYN1;GLRA1;CACNA1G;GLRB;VDAC1;HTR2A;GLRA3;OPRM1;OPRD1 GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 GO:0007165| signal transduction HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;BST1;CACNA1I GO:0032868| response to insulin stimulus TRPV4;PFKFB1;AANAT;CAT 17847:[DB14011 DB08574] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 17848:[DB14011 DB07768] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;PTGS1;NAAA;GPX1;PPARG;CYP2C9;AKR1C2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9;PTGS1;AKR1C1;CYP3A4;CYP3A7;CYP1A2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2;AKR1C2 GO:0042448| progesterone metabolic process CYP17A1;AKR1C2;AKR1C1 GO:0001523| retinoid metabolic process NAPEPLD;AKR1C1 GO:0008284| positive regulation of cell proliferation AKR1C2;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C2;GPX1 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;AKR1C1;ALOX5;PTGS1;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;AKR1C2 GO:0051260| protein homooligomerization GLRA1;ACAT1;GLRA3;AKR1C1 GO:0042574| retinal metabolic process CYP1B1;AKR1C1 GO:0007186| G-protein coupled receptor signaling pathway AKR1C2;GPR18;PPARG;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0008202| steroid metabolic process CYP2D6;AKR1C2;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0030855| epithelial cell differentiation AKR1C1;PPARG;AKR1C2;VDAC1 17849:[DB14011 DB01053] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0034220| ion transmembrane transport CHRNA7;GLRA3;SLC22A4;GLRB;TRPV1;GLRA1;TRPA1 GO:0055085| transmembrane transport SLC15A1;TRPA1;SLC22A6;CACNA1G;ABCC1;ABCG2;TRPM8;SLCO2B1;TRPV1;TRPV4;CACNA1I;VDAC1;SLCO1B1;SLC22A5;SLC15A2;SLC22A8;CACNA1H;SLCO3A1;TRPV3;SLC22A4;SLCO4A1;SLC22A11;TRPV2 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0006810| transport SLC15A2;TRPV2;ABCC1;SLC15A1;TRPV1;CACNA1I;ABCG2 GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0009636| response to toxin SLC22A8;CAT;GPX1;CYP1A1;CYP1B1 GO:0006811| ion transport TRPA1;GLRA1;SLC15A1;CACNA1G;TRPM8;SLCO2B1;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;SLC15A2;SLC22A5;GLRA3;SLC22A8;SLCO1B1;CACNA1H;SLC22A4;SLCO3A1;TRPV3;SLCO4A1;SLC22A11;CHRNA7;TRPV2 GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCG2 GO:0006641| triglyceride metabolic process GPX1;CAT;SLC22A4 GO:0046415| urate metabolic process ABCG2;SLC22A11 17850:[DB14011 DB00350] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00350|Minoxidil KCNJ1;PTGS1;REN;UGT1A1 common genes PTGS1 common pathways GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0008152| metabolic process ACAT1;UGT1A1;SMPD1 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;UGT1A1 GO:0048469| cell maturation PPARG;REN GO:0001889| liver development UGT1A1;CYP1A1;ACAT1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;PTGS2;CNR2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0034765| regulation of ion transmembrane transport CACNA1H;CACNA1G;KCNJ1;CACNA1I GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0007584| response to nutrient HMGCR;CNR1;UGT1A1;PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;REN;PPARG GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;KCNJ1;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1;UGT1A1 GO:0035902| response to immobilization stress CYP1A2;REN;CYP1A1;PPARG GO:0042594| response to starvation PPARG;UGT1A1;ACAT1 GO:0001822| kidney development REN;CAT GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;UGT1A1;REN;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;UGT1A1;TRPA1;REN;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0017144| drug metabolic process CYP1A1;CYP2C9;UGT1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| PTGS2;CAT;PTGS1;GPX1;GSR GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP1A1;CYP2C9;UGT1A1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;UGT1A1;TRPA1;REN;CYP1A1;PPARG GO:0051591| response to cAMP AANAT;REN 17851:[DB14011 DB06830] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process HMGCR;GGPS1 GO:0008299| isoprenoid biosynthetic process HMGCR;GGPS1 GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1 17852:[DB14011 DB03247] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0006355| regulation of transcription, DNA-dependent RPS6KA4;PPARG GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;DHODH;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;POR GO:0022900| electron transport chain CYP1A2;POR;GSR;IDO1 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;PPARG GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0055114| oxidation-reduction process HAO1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;DPYD;CAT;HAO2;PNPO;DHODH;CYP2C9;CYP1A1;NOS1;BLVRB;CRYZ;POR;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19 GO:0009062| fatty acid catabolic process FAAH;HAO2 GO:0042127| regulation of cell proliferation SGK1;PTGS2;PTGS1 GO:0009812| flavonoid metabolic process CYP1A1;POR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NOS1;RPS6KA4 GO:0043066| negative regulation of apoptotic process POR;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0042311| vasodilation NOS1;GPX1 GO:0042594| response to starvation ACAT1;DHODH;PPARG GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;SGK1;TRPV1;GLRB GO:0006915| apoptotic process GPX1;RFK;SGK1;VDAC1 GO:0001666| response to hypoxia CHRNA7;CAT;NOS1;CYP1A1 GO:0031000| response to caffeine PPARG;DHODH GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;NOS1;TRPV1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;HAO1;SOD1 GO:0032793| positive regulation of CREB transcription factor activity RPS6KA4;OPRD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;NOS1;CYP2C19 GO:0007565| female pregnancy DHODH;IDO1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;POR GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;PTGS1;ALOX5;RPS6KA4 GO:0009408| response to heat SOD1;TRPV3;TRPV2;NOS1;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;RPS6KA4 GO:0007595| lactation SLC29A1;DHODH GO:0045776| negative regulation of blood pressure NOS1;CNR1 GO:0070988| demethylation POR;CYP1A1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2;DHODH GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;POR;CYP1B1;CYP2C9 GO:0035556| intracellular signal transduction RPS6KA4;PLA2G1B;SGK1 GO:0042136| neurotransmitter biosynthetic process NOS1;DAGLA GO:0043267| negative regulation of potassium ion transport NOS1;HTR2A GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;DHODH;CYP1A2;PTGS2 GO:0033555| multicellular organismal response to stress NOS1;IDO1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS1 GO:0019395| fatty acid oxidation PPARG;POR;HAO2 GO:0007584| response to nutrient POR;PPARG;HMGCR;CNR1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;SGK1;PPARG GO:0072593| reactive oxygen species metabolic process SOD1;RFK GO:0045454| cell redox homeostasis NOS1;GSR;GPX1 GO:0007520| myoblast fusion CACNA1H;NOS1 GO:0015937| coenzyme A biosynthetic process PPCDC;ACAT1 17853:[DB14011 DB03907] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0032259| methylation CYP1A2;COMT GO:0007612| learning PTGS2;COMT;VDAC1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CYP1A1;COMT;IDO1 GO:0007614| short-term memory COMT;CHRNA7 GO:0008210| estrogen metabolic process COMT;CYP1B1 GO:0048265| response to pain TRPV1;TRPA1;COMT GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;COMT;TRPA1;PPARG;CYP1A1;ABCG2 GO:0007565| female pregnancy COMT;IDO1 GO:0048662| negative regulation of smooth muscle cell proliferation COMT;PPARG GO:0032502| developmental process COMT;CYP1A1 GO:0043627| response to estrogen stimulus PPARG;COMT GO:0051930| regulation of sensory perception of pain COMT;OPRM1;OPRD1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;COMT;CYP1A1;PPARG;TRPA1 17854:[DB14011 DB06354] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways GO:0034220| ion transmembrane transport CHRNA7;GRIK1;GLRA3;TRPV1;GLRB;TRPA1;GLRA1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;GRIK1;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;GABBR1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0006810| transport GRIK1;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;GRIK1;SLC29A1;GLRA1;TRPV1;GLRB GO:0051966| regulation of synaptic transmission, glutamatergic CNR1;GRIK1 GO:0006811| ion transport TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;GLRA1;TRPA1;CACNA1G;CHRNA7;GRIK1;TRPV2;GLRA3;TRPV3;CACNA1H GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GABBR1;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;GABBR1 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GRIK1;GLRA1;CACNA1G;VDAC1;GLRB GO:0007399| nervous system development SMPD1;GLRB;GRIK1 GO:0007194| negative regulation of adenylate cyclase activity GABBR1;OPRM1 17855:[DB14011 DB12773] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12773|Sifalimumab IFNA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IFNA2 GO:0045087| innate immune response IFNA2;PPARG GO:0006915| apoptotic process VDAC1;GPX1;IFNA2 GO:0045892| negative regulation of transcription, DNA-dependent IFNA2;PPARG GO:0010629| negative regulation of gene expression OPRD1;IFNA2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PTGS1;ALOX5;IFNA2;CNR2;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNA2 17856:[DB14011 DB04893] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04893|AZD3409 FNTB;FNTA common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;PTGS2;FNTB 17857:[DB14011 DB07068] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07068|(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID PTPRB common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;PTPRB GO:0001525| angiogenesis PTPRB;CYP1B1;PTGS2 17858:[DB14011 DB04521] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04521|GSHNA GSTA3 common genes common pathways GO:0006749| glutathione metabolic process GSR;GPX1;GSTA3;SOD1 GO:0008152| metabolic process SMPD1;ACAT1;GSTA3 17859:[DB14011 DB07400] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07400|1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation F2;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 17860:[DB14011 DB04756] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;TTR GO:0006810| transport TRPV2;TTR;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process NAPEPLD;TTR 17861:[DB14011 DB02018] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02018|Amido Phenyl Pyruvic Acid TPSB2 common genes common pathways 17862:[DB14011 DB11731] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification EGFR;ALOX15 GO:0035556| intracellular signal transduction PLA2G1B;EGFR GO:0051592| response to calcium ion AANAT;EGFR GO:0001889| liver development ACAT1;CYP1A1;EGFR GO:0007166| cell surface receptor linked signaling pathway EGFR;TRPV1;TRPA1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0006970| response to osmotic stress TRPV4;EGFR GO:0032930| positive regulation of superoxide anion generation SOD1;EGFR GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;EGFR GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0071276| cellular response to cadmium ion EGFR;SOD1;CYP1A2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;EGFR;CYP1A2;PTGS2;AANAT;ACAT1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;EGFR GO:0007165| signal transduction EGFR;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;EGFR GO:0045907| positive regulation of vasoconstriction EGFR;HTR2A;PTGS2 GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response EGFR;TRPV4 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;EGFR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;EGFR GO:0043312| neutrophil degranulation TUBB;ALOX5;CAT GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;EGFR GO:0008284| positive regulation of cell proliferation EGFR;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;PLA2G1B;PPARG GO:0030324| lung development EGFR;CYP1A2 GO:0071230| cellular response to amino acid stimulus GLRA1;EGFR GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0042127| regulation of cell proliferation EGFR;PTGS2;PTGS1 GO:0042060| wound healing ALOX15;EGFR;OPRM1 GO:0007623| circadian rhythm EGFR;AANAT GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;EGFR GO:0007202| activation of phospholipase C activity EGFR;HTR2A;GPR55 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;EGFR;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;EGFR;TRPV1 GO:0006979| response to oxidative stress EGFR;CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0033993| response to lipid PPARG;EGFR GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;EGFR GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;CAT;OPRD1 17863:[DB14011 DB04753] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;TRPA1;PPARG;PNP;CYP1A1;SMPD1;ABCC1;ABCG2 GO:0043312| neutrophil degranulation CAT;ALOX5;PNP GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0006955| immune response PNP;CNR2;OPRD1 17864:[DB14011 DB07522] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07522|N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE F2 common genes common pathways GO:0061844| F2;PLA2G1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;F2;GPR18;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;F2 17865:[DB14011 DB01033] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes SLC29A1 common pathways GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PPAT GO:0001975| response to amphetamine CNR2;SOD1;HPRT1 GO:0098656| VDAC1;SLC22A8 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;ABCC4;CYP1A2;PTGS2 GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0006919| activation of caspase activity PPARG;XDH GO:0008283| cell proliferation HTR1A;SLC29A2;GPX1;CYP1A1 GO:0006139| nucleobase-containing compound metabolic process SLC29A2;SLC28A2;SLC29A1;TPMT GO:0006811| ion transport CHRNA7;TRPV2;SLC22A8;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPA1;GLRA1;CACNA1G GO:0015862| uridine transport SLC29A1 GO:0008152| metabolic process SMPD1;PPAT;ACAT1 GO:0030431| sleep CACNA1I;SLC29A1;HTR2A GO:0007595| lactation PPAT;SLC29A1;XDH GO:0015858| nucleoside transport SLC29A2;SLC29A1 GO:0051289| protein homotetramerization CAT;PPAT;IMPDH2;HPRT1;TRPV1;TRPM8;TRPA1;CRYZ GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0010629| negative regulation of gene expression XDH;OPRD1 GO:0017144| drug metabolic process AOX1;CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0031100| organ regeneration PPAT;PPARG GO:0006810| transport TRPV2;ABCG2;ABCC5;CACNA1I;TRPV1;ABCC1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:1901642| SLC29A2;SLC28A3;SLC28A2;SLC29A1 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;PTGS2;CYP1A2;ABCC4 GO:0055085| transmembrane transport ABCC5;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G;ABCC4;TRPV2;SLC22A8;TRPV3;CACNA1H GO:0043312| neutrophil degranulation CAT;ALOX5;IMPDH2;IMPDH1 GO:0001822| kidney development PPAT;CAT GO:0032259| methylation CYP1A2;TPMT GO:0007626| locomotory behavior OPRM1;SOD1;HPRT1 GO:0002576| platelet degranulation ABCC4;SOD1 GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;TRPV1;GLRB;GLRA1 GO:0060135| maternal process involved in female pregnancy PPAT;CNR1 GO:0007623| circadian rhythm IMPDH2;AANAT GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;ABCC4 GO:0010243| response to organic nitrogen PTGS2;ABCC4;TRPV1 GO:0055114| oxidation-reduction process HMGCR;XDH;CYP1A2;PTGS2;CYP3A7;SOD1;IMPDH2;CYP3A4;ABCC4;GPX1;ALOX5;PTGS1;CAT;CRYZ;AOX1;CYP1A1;CYP2C9;IMPDH1;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1 GO:0022900| electron transport chain IDO1;GSR;AOX1;CYP1A2;XDH GO:0099133| ABCC4;ABCC5;ABCC1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT;PPAT;ABCC4 17866:[DB14011 DB02264] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02264|O2-Sulfo-Glucuronic Acid FGF1;HGF;HS3ST3A1 common genes common pathways GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;HGF GO:0034605| cellular response to heat FGF1;PTGS2;TRPV1;TRPV4 GO:0031100| organ regeneration HGF;PPARG GO:0045766| positive regulation of angiogenesis CYP1B1;HGF;FGF1;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;FGF1;SOD1;HGF;PLA2G1B GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF1 GO:0030324| lung development FGF1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;PPARG;HGF;PLA2G1B GO:0008284| positive regulation of cell proliferation HTR2A;FGF1;HTR1A;HMGCR;PTGS2;CHRNA7;HGF GO:0002576| platelet degranulation SOD1;HGF GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;HGF GO:0051897| positive regulation of protein kinase B signaling cascade HGF;FGF1;GPX1 GO:0060326| cell chemotaxis ABCC1;HGF GO:0050728| negative regulation of inflammatory response HGF;CNR2 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;HGF GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;FGF1;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0008283| cell proliferation CYP1A1;HGF;HTR1A;FGF1;GPX1 GO:0051450| myoblast proliferation GPX1;HGF GO:1902042| GPX1;HGF GO:0051781| positive regulation of cell division CAT;FGF1 GO:0001525| angiogenesis CYP1B1;PTGS2;FGF1 GO:0001889| liver development HGF;CYP1A1;ACAT1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;FGF1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process HGF;PTGS2;GPX1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;HGF 17867:[DB14011 DB05883] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05883|ABX-PTH PTH common genes common pathways GO:0033280| response to vitamin D PTGS2;PTH GO:0045453| bone resorption GPR55;PTH GO:0031667| response to nutrient levels PTH;SOD1 GO:0045471| response to ethanol CNR1;SOD1;OPRM1;HMGCR;PTH;CAT GO:0046686| response to cadmium ion CAT;PTH GO:0007202| activation of phospholipase C activity PTH;GPR55;HTR2A GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;PTH;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0010468| regulation of gene expression CYP1A2;PTH GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;PTH;CHRNA7;TRPM8;TRPV4 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2;PTH GO:0045944| positive regulation of transcription from RNA polymerase II promoter PTH;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PTH;TRPV4;TRPV1;PPARG GO:0010288| response to lead ion CAT;PTH 17868:[DB14011 DB08814] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes PTGS1 common pathways GO:0045454| cell redox homeostasis GPX1;GSR;NOS2 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;PDE10A;CHRNA7;NFKB1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0001895| retina homeostasis ALB;SOD1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NFKB1 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0006351| transcription, DNA-dependent NFKB1;PPARG GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0008152| metabolic process ACAT1;PDE10A;SMPD1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;NAAA;GPX1;PTGS1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0010629| negative regulation of gene expression NOS2;OPRD1;NFKB1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;NFKB1;CAT GO:0006954| inflammatory response PTGS2;CNR2;NFKB1;PTGS1;ALOX5;ALOX15;IDO1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway PDE10A;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0098869| ALB;GSR;CAT;GPX1;PTGS1;PTGS2 GO:0006915| apoptotic process VDAC1;GPX1;NFKB1 GO:0001666| response to hypoxia NOS2;CYP1A1;CHRNA7;CAT GO:0071356| cellular response to tumor necrosis factor TRPV1;NFKB1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NFKB1 GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NOS2 GO:0032496| response to lipopolysaccharide CYP1A1;NOS2;IDO1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0002576| platelet degranulation SOD1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process ALB;CAT;NFKB1;GPX1;SOD1;PTGS2;HMGCR GO:0045087| innate immune response NFKB1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;NFKB1 GO:0043312| neutrophil degranulation ALOX5;CAT;NFKB1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NFKB1 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;NOS2;CRYZ;CYP1A1;CYP2C9;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0050728| negative regulation of inflammatory response CNR2;NFKB1 17869:[DB14011 DB07443] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0031000| response to caffeine PPARG;DHODH GO:0042594| response to starvation ACAT1;DHODH;PPARG GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;DHODH;ALOX5;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1 GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;DHODH;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;DHODH;ACAT1;AANAT GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;DHODH;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0007565| female pregnancy IDO1;DHODH GO:0007595| lactation DHODH;SLC29A1 17870:[DB14011 DB07032] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR2 GO:0007165| signal transduction HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;ESR2;PLA2G1B;CACNA1I GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR2 GO:0006351| transcription, DNA-dependent PPARG;ESR2 17871:[DB14011 DB09272] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes OPRM1;OPRD1 common pathways GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:0007626| locomotory behavior OPRK1;SOD1;OPRM1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRD1;OPRM1;OPRK1;GLRB;GLRA1 GO:0042060| wound healing ALOX15;OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;CYP1A1;IDO1;ABCC2 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0097237| OPRD1 GO:0032100| positive regulation of appetite OPRM1 GO:0032094| response to food CYP1A1;OPRM1 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCC2;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0006979| response to oxidative stress ABCC2;CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;GPR18;PPARG;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0006810| transport ABCG2;ABCC2;TRPV1;CACNA1I;ABCC1;TRPV2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;CNR2;OPRM1 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0042220| response to cocaine OPRK1;SMPD1;CNR1;OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0055085| transmembrane transport ABCC2;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;ABCC1;CACNA1G;TRPV2;SLCO1B1;SLC22A8;TRPV3;CACNA1H GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0009314| response to radiation CAT;PTGS2;OPRM1;OPRK1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain OPRK1;TRPV1;TRPA1;HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0045471| response to ethanol OPRK1;CAT;CNR1;SOD1;OPRM1;HMGCR GO:0006955| immune response CNR2;OPRD1;OPRK1 GO:0009408| response to heat TRPV1;ABCC2;TRPV2;TRPV3;SOD1 GO:0007600| sensory perception TRPV2;OPRM1;OPRK1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission GLRA1;CACNA1G;OPRK1;VDAC1;GLRB;HTR2A;GLRA3;OPRD1;OPRM1 GO:0010629| negative regulation of gene expression OPRD1 GO:0007565| female pregnancy ABCC2;IDO1 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0044849| OPRM1;OPRK1 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;TRPV3;CACNA1H;OPRM1;CHRNA7;TRPV2 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;OPRK1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0007610| behavior HTR2A;HTR1A;OPRK1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0098656| SLC22A8;VDAC1 GO:0043627| response to estrogen stimulus ABCC2;OPRK1;PPARG GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;SLC22A8;GLRA3;SLCO1B1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0032868| response to insulin stimulus TRPV4;OPRK1;AANAT;CAT GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 17872:[DB14011 DB07625] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07625|4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;PLAU GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLAU GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;PLAU;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 17873:[DB14011 DB00024] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00024|Thyrotropin alfa TSHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;TSHR GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger TSHR;CNR2;OPRM1;OPRD1;CNR1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;TSHR GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;TSHR;CHRNA7 GO:0007399| nervous system development GLRB;SMPD1;TSHR GO:0007166| cell surface receptor linked signaling pathway TSHR;TRPV1;TRPA1 17874:[DB14011 DB03616] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03616|Kabiramide C ACTA1 common genes common pathways GO:0010226| response to lithium ion PTGS2;ACTA1 GO:0006936| muscle contraction ACTA1;CACNA1H;GLRA1 GO:0010628| positive regulation of gene expression TRPV4;ACTA1 GO:0048741| skeletal muscle fiber development GPX1;ACTA1 GO:0009612| response to mechanical stimulus PPARG;TRPV4;ACTA1 17875:[DB14011 DB04232] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04232|N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide MMP3 common genes common pathways 17876:[DB14011 DB00657] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes CHRNA7 common pathways GO:0060078| regulation of postsynaptic membrane potential CHRNB2;CHRNA7;CHRNA2 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;SOD1;CNR1;CHRNB2 GO:0019233| sensory perception of pain TRPV1;CHRNB2;TRPA1;CHRNA4;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:1902430| CHRNA7 GO:0006816| calcium ion transport CACNA1H;TRPV3;CHRNA7;CHRNA4;TRPV2;TRPA1;CACNA1G;CHRNB2;TRPM8;CACNA1I;TRPV4;TRPV1 GO:0008542| visual learning CHRNB2;HMGCR GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;CHRNA4;GLRA1;CACNA1G;GLRB;VDAC1 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902004| CHRNA7 GO:0006939| smooth muscle contraction CHRNB2;HTR2A GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;TRPV3;CACNA1H;OPRM1;CHRNA7;TRPV2 GO:1900273| CHRNA7 GO:1904645| CHRNA7 GO:0007165| signal transduction GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;CHRNA2;CHRNA4;GPR18;PPARG;SMPD1;CHRNB2;PLA2G1B;CACNA1I GO:0050890| cognition CHRNA7;CHRNA4;CHRNB2 GO:0097061| dendritic spine organization CHRNA7 GO:0007613| memory CHRNB2;CHRNA7;PTGS2;CNR1;HTR2A GO:0007601| visual perception CRYZ;GLRA1;CHRNB2;CYP1B1;GLRB GO:0042053| regulation of dopamine metabolic process HTR1A;CHRNB2 GO:0051291| protein heterooligomerization GLRA1;CHRNB2;GLRB;CHRNA2 GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;CHRNB2;TRPA1;GLRA1;CHRNA4;TRPV2;CHRNA2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0007626| locomotory behavior CHRNB2;CHRNA4;OPRM1;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0007612| learning PTGS2;VDAC1;CHRNB2 GO:0001508| regulation of action potential CHRNB2;CACNA1G;GLRA1;CHRNA4 GO:0007611| learning or memory CHRNA7;CNR1 GO:1905144| CHRNA7;CHRNB2 GO:0007614| short-term memory CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;CHRNB2;GLRA1;SLC29A1;CHRNA2;CHRNA4;CHRNA7;OPRM1;GLRA3 GO:1905906| CHRNA7 GO:0050893| sensory processing CHRNA7 GO:0035640| exploration behavior HTR1A;CHRNA4 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0035094| response to nicotine CHRNA7;CHRNA2;CHRNA4;CNR1;CHRNB2 GO:0050808| synapse organization CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 GO:1901214| CHRNA7 GO:0006979| response to oxidative stress CHRNA4;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;GPR12;HTR2A;CHRNA7 GO:0042391| regulation of membrane potential CACNA1H;CHRNA4;CHRNB2;CACNA1G;GLRA1;GLRB GO:0007605| sensory perception of sound SOD1;GPX1;CHRNB2 GO:0045759| negative regulation of action potential CHRNB2;CNR2;CNR1 GO:0098815| CHRNA7 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CHRNA4;CAT;CHRNA7;CHRNB2;CYP1A1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:1902991| CHRNA7 GO:0014059| regulation of dopamine secretion CHRNB2;CHRNA4;HTR2A GO:0060080| regulation of inhibitory postsynaptic membrane potential CHRNA4;GLRA1 GO:0095500| CHRNA4;CHRNA7;CHRNB2 GO:0034220| ion transmembrane transport GLRB;TRPV1;GLRA1;TRPA1;CHRNB2;CHRNA7;CHRNA2;CHRNA4;GLRA3 GO:1905920| CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7 GO:0042220| response to cocaine SMPD1;CHRNB2;CNR1;OPRM1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 17877:[DB14011 DB08844] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;SLC22A8;TRPV2;CHRNA7 GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0046415| urate metabolic process SLC2A9;ABCG2 GO:0008152| metabolic process PYGL;SMPD1;ACAT1 GO:0055085| transmembrane transport TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;CACNA1I;TRPV4;VDAC1;SLC22A8;SLC2A9;TRPV3;CACNA1H;TRPV2 GO:0015758| glucose transport SLC2A9;PLA2G1B GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;PYGL GO:0051260| protein homooligomerization SLC22A6;GLRA1;ACAT1;GLRA3 GO:0043312| neutrophil degranulation CAT;ALOX5;PYGL 17878:[DB14011 DB07557] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07557|(5BETA)-PREGNANE-3,20-DIONE NCOA1;RXRA;NR1I3;AKR1D1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;NR1I3 GO:0055114| oxidation-reduction process CYP3A4;SOD1;AKR1D1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;NCOA1 GO:0006355| regulation of transcription, DNA-dependent RXRA;PPARG;NCOA1;NR1I3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;NCOA1;RXRA;PPARG;PLA2G1B GO:0032526| response to retinoic acid RXRA;PPARG GO:0008203| cholesterol metabolic process CAT;HMGCR;RXRA GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I3 GO:0016042| lipid catabolic process AKR1D1;NAPEPLD;PLA2G1B;DAGLA GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP3A4;AKR1D1;CYP3A7;CYP1A2;HMGCR GO:0016032| viral reproduction HTR2A;VDAC1;RXRA GO:0051289| protein homotetramerization CAT;TRPM8;TRPV1;TRPA1;RXRA;CRYZ GO:0008209| androgen metabolic process AKR1D1;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;PTGS2;AKR1D1;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6 GO:0007507| heart development PPARG;RXRA GO:0043065| positive regulation of apoptotic process CNR1;SOD1;NCOA1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0006351| transcription, DNA-dependent NR1I3;NCOA1;PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG;NR1I3 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0001890| placenta development RXRA;PPARG;SOD1 GO:0007165| signal transduction CHRNA7;NR1I3;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0032870| cellular response to hormone stimulus NCOA1;CACNA1H GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;HMGCR;CNR1;NCOA1 GO:0007566| embryo implantation RXRA;PTGS2;SOD1 17879:[DB14011 DB01375] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01375|Aluminium monostearate TNNC1;VDAC1;VDAC2;VDAC3 common genes VDAC1 common pathways GO:0055085| transmembrane transport TRPV3;CACNA1H;VDAC2;VDAC3;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;TRPV4;CACNA1I GO:0006915| apoptotic process GPX1;VDAC1 GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0006820| anion transport VDAC1;GLRA1;VDAC2 GO:1903146| VDAC1 GO:0016236| macroautophagy VDAC1 GO:0007612| learning VDAC3;PTGS2;VDAC1 GO:0001662| behavioral fear response VDAC1;VDAC3;HTR1A GO:0006851| mitochondrial calcium ion transport VDAC1 GO:0098656| VDAC1;VDAC3;VDAC2 GO:0006811| ion transport TRPV2;VDAC3;VDAC2;CHRNA7;CACNA1H;TRPV3;GLRA3;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1 GO:0007270| neuron-neuron synaptic transmission VDAC1;VDAC3 GO:0016032| viral reproduction VDAC1;HTR2A GO:0007268| synaptic transmission VDAC1;GLRB;CACNA1G;GLRA1;VDAC3;OPRM1;OPRD1;HTR2A;GLRA3 17880:[DB14011 DB07945] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07945|5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid FABP4 common genes common pathways GO:0071356| cellular response to tumor necrosis factor TRPV1;FABP4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;FABP4 GO:0050729| positive regulation of inflammatory response FABP4;TRPV4 GO:0050872| white fat cell differentiation PPARG;FABP4 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0050873| brown fat cell differentiation PTGS2;FABP4 17881:[DB14011 DB09110] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09110|Coenzyme M GSR common genes GSR common pathways GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1A1;CYP2C9;CRYZ GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;GSR GO:0098869| GSR;PTGS2;CAT;GPX1;PTGS1 GO:0006749| glutathione metabolic process GSR;GPX1;SOD1 GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0045454| cell redox homeostasis GPX1;GSR 17882:[DB14011 DB08382] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08382|Gosogliptin DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 17883:[DB14011 DB09460] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0001822| kidney development CA2;CAT GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CA9;CAT GO:0001666| response to hypoxia CYP1A1;CA9;CHRNA7;CAT GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG;CA2 17884:[DB14011 DB01405] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes CYP1A2 common pathways GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;CYP1A1;PPARG;TRPA1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 17885:[DB14011 DB02613] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy IDO1;DHODH GO:0043065| positive regulation of apoptotic process DHODH;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;PNLIPRP2;NAAA;GPX1;PTGS1 GO:0009395| phospholipid catabolic process NAPEPLD;PNLIPRP2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;DHODH;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0006641| triglyceride metabolic process GPX1;PNLIPRP2;CAT GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;DHODH;CAT;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1;ALOX5;GPX1;PTGS1;DHODH;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0031000| response to caffeine DHODH;PPARG GO:0016042| lipid catabolic process PLA2G1B;DAGLA;NAPEPLD;PNLIPRP2 17886:[DB14011 DB07324] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07324|3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE HSP90AA1 common genes common pathways GO:0007165| signal transduction SMPD1;HSP90AA1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;HSP90AA1 GO:0009409| response to cold TRPM8;HSP90AA1;PPARG;TRPA1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HSP90AA1;PTGS2;OPRM1 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT 17887:[DB14011 DB13873] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes PPARG common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARD;NR1I2;PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARD;PPARG;NR1I2 GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0048469| cell maturation PPARG GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;NR1I2;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;PPARA;PPARD;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARA;PPARD;PPARG GO:0045165| cell fate commitment PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0042738| exogenous drug catabolic process CYP2C9;NR1I2;CYP2C19;CYP1A2;CYP3A4 GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0050872| white fat cell differentiation PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;PPARA;CNR1;HMGCR GO:0007566| embryo implantation SOD1;PPARD;PTGS2 GO:1905461| PPARG GO:0042908| xenobiotic transport ABCC1;NR1I2;ABCG2 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;NR1I2;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;PTGS2;CYP1A2 GO:0008283| cell proliferation CYP1A1;PPARD;HTR1A;GPX1 GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT;PPARA GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;PPARD;SOD1 GO:0019395| fatty acid oxidation PPARG;PPARD GO:0060612| adipose tissue development PPARD;ACAT1 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARD;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0014823| response to activity CAT;PPARD GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0008203| cholesterol metabolic process CAT;HMGCR;PPARD GO:0042127| regulation of cell proliferation PTGS2;PPARD;PTGS1 GO:0042060| wound healing ALOX15;OPRM1;PPARD;PPARA GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0032526| response to retinoic acid PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;PPARD GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PLA2G1B;PPARG;NR1I2 GO:0008284| positive regulation of cell proliferation HMGCR;PPARD;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARD;PPARG;TRPV1;TRPV4 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PPARA;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG;PPARD;PPARA GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;NR1I2;PPARG GO:0030224| monocyte differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0050728| negative regulation of inflammatory response PPARA;PPARD;CNR2 GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT;PPARD GO:0016525| negative regulation of angiogenesis PPARG GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARD;NR1I2;PPARG GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP2C9;CYP1A1;NR1I2;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0015909| long-chain fatty acid transport PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0046697| decidualization PPARD;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;PPARD;SLC29A1 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0006915| apoptotic process VDAC1;PPARD;GPX1 GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;PPARA GO:0010628| positive regulation of gene expression TRPV4;NR1I2;PPARD GO:0010033| response to organic substance PTGS2;CYP1A2;PPARD;SOD1;PPARG;CYP1A1;TRPA1 GO:0031000| response to caffeine PPARG GO:0015758| glucose transport PLA2G1B;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;NR1I2;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG 17888:[DB14011 DB05361] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0009611| response to wounding GPX1;F2R;CYP1A1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;F2R;TRPA1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;F2R;GPR55;GPR18;PPARG GO:0035025| positive regulation of Rho protein signal transduction GPR18;GPR55;F2R GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2R GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;F2R;GPR18 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;F2R;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2R GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;F2R;IDO1;CYP1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;F2R;OPRD1;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;F2R GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;F2R GO:0007165| signal transduction GPR55;F2R;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0099553| CNR1;F2R GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;F2R;TRPV4;TRPV1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;F2R GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;F2R;CYP1B1;PPARG GO:0007584| response to nutrient SERPINC1;CNR1;HMGCR;PPARG GO:0006919| activation of caspase activity PPARG;F2R GO:0051930| regulation of sensory perception of pain F2R;OPRD1;OPRM1 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;F2R;TRPV1;ALOX15;IDO1 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;F2R GO:0007595| lactation SLC29A1;SERPINC1 GO:0043524| negative regulation of neuron apoptosis F2R;SOD1 17889:[DB14011 DB08784] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 17890:[DB14011 DB02285] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02285|Protoporphyrin FTL common genes common pathways GO:0006879| cellular iron ion homeostasis ABCG2;FTL;SOD1 GO:0043312| neutrophil degranulation CAT;FTL;ALOX5 17891:[DB14011 DB00038] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00038|Oprelvekin IL11RA common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;IL11RA GO:0032502| developmental process CYP1A1;IL11RA GO:0007566| embryo implantation IL11RA;SOD1;PTGS2 17892:[DB14011 DB07249] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07249|N-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine EPHB4 common genes common pathways GO:0001525| angiogenesis EPHB4;CYP1B1;PTGS2 GO:0007155| cell adhesion CYP1B1;EPHB4 17893:[DB14011 DB00512] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00512|Vancomycin ALB;ORM1;ORM2 common genes common pathways GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;ORM1;ALOX15;IDO1;TRPV1 GO:0001895| retina homeostasis SOD1;ALB GO:0002576| platelet degranulation SOD1;ORM2;ORM1;ALB GO:0043066| negative regulation of apoptotic process ALB;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0043312| neutrophil degranulation ALOX5;CAT;ORM1;ORM2 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;ORM1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR 17894:[DB14011 DB04448] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04448|2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene ADH1C common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;ADH1C;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ 17895:[DB14011 DB06231] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06231|Caldaret SLC8A1 common genes common pathways GO:0051481| reduction of cytosolic calcium ion concentration SLC8A1;OPRM1 GO:0070509| calcium ion import CACNA1G;TRPV4;CACNA1I;CACNA1H;SLC8A1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2;SLC8A1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;SLC8A1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0071456| cellular response to hypoxia SLC8A1;SLC29A1;PTGS2;OPRD1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;SLC8A1;HTR2A;GPR12 GO:0006936| muscle contraction GLRA1;SLC8A1;CACNA1H GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC8A1;TRPV2;ABCC1;CACNA1G;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;SLC8A1 GO:0035725| sodium ion transmembrane transport SLC8A1;CACNA1H;CACNA1I;CACNA1G GO:0060078| regulation of postsynaptic membrane potential CHRNA7;SLC8A1 GO:0002027| regulation of heart rate CACNA1G;SLC8A1 GO:0042542| response to hydrogen peroxide SOD1;GPX1;SLC8A1;CAT;TRPA1 GO:0071320| cellular response to cAMP SLC8A1;AANAT GO:0051924| regulation of calcium ion transport OPRD1;SLC8A1 GO:0006816| calcium ion transport CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8;TRPV3;CACNA1H;TRPV2;SLC8A1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;OPRM1;SLC8A1 GO:0070588| calcium ion transmembrane transport TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;CHRNA7;SLC8A1;TRPV2;TRPV3;OPRM1;CACNA1H GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;SLC8A1;TRPV2;CHRNA7 GO:0007584| response to nutrient HMGCR;CNR1;SLC8A1;PPARG 17896:[DB14011 DB00733] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00733|Pralidoxime ACHE;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation CYP1B1;BCHE;PPARG;OPRM1;PTGS2 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0008283| cell proliferation CYP1A1;ACHE;HTR1A;GPX1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;BCHE;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007612| learning BCHE;VDAC1;PTGS2 17897:[DB14011 DB03189] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03189|Cu-Cyclam LYZ common genes common pathways GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;IDO1;ALOX15;LYZ;TRPV1 GO:0008152| metabolic process ACAT1;SMPD1;LYZ GO:0001895| retina homeostasis SOD1;LYZ GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LYZ GO:0043312| neutrophil degranulation LYZ;CAT;ALOX5 17898:[DB14011 DB00160] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0048148| behavioral response to cocaine ABAT;HTR2A GO:0045471| response to ethanol ABAT;CAT;HMGCR;OPRM1;SOD1;CNR1 GO:0045776| negative regulation of blood pressure ABAT;CNR1 GO:1902476| GLRB;SLC1A4;GLRA1;GLRA3 GO:0043524| negative regulation of neuron apoptosis SOD1;AARS GO:0050890| cognition CHRNA7;SLC1A4 GO:0051384| response to glucocorticoid stimulus PTGS2;AGXT GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;SLC7A8 GO:0006811| ion transport SLC36A1;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0007626| locomotory behavior OPRM1;SOD1;ABAT GO:0033602| negative regulation of dopamine secretion CNR1;ABAT GO:0035094| response to nicotine CNR1;CHRNA7;ABAT GO:0035640| exploration behavior ABAT;HTR1A GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABAT;ABCG2 GO:0050905| neuromuscular process GLRA1;GLRB;AARS GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;AGXT2;TRPV1 GO:0006810| transport SLC7A8;TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0007568| aging HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CAT;CYP1A1;ABAT GO:0006569| tryptophan catabolic process IDO1;KYNU GO:0019441| tryptophan catabolic process to kynurenine KYNU;IDO1 GO:0001666| response to hypoxia ABAT;CYP1A1;CHRNA7;CAT GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;ABAT GO:0055085| transmembrane transport SLC36A1;TRPV2;CACNA1H;SLC16A10;TRPV3;ABCG2;TRPM8;SLC1A4;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0051591| response to cAMP AGXT;AANAT 17899:[DB14011 DB04246] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04246|CRA_23653 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 17900:[DB14011 DB03020] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03020|5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;ADH1C;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2 17901:[DB14011 DB00596] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;TRPV1;TRPV4 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;NR3C1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 17902:[DB14011 DB07008] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GSR;NOS2;GPX1 GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0007623| circadian rhythm NOS2;AANAT GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;NOS2;CYP1A1;IDO1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;NOS2 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 17903:[DB14011 DB00094] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00094|Urofollitropin FSHR common genes common pathways GO:0007165| signal transduction FSHR;CHRNA7;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;FSHR;GPR18;PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FSHR GO:0007283| spermatogenesis FSHR;SOD1;CNR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;FSHR;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 17904:[DB14011 DB09395] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09395|Sodium acetate ACSS2 common genes common pathways GO:0006085| acetyl-CoA biosynthetic process ACAT1;ACSS2 GO:0008152| metabolic process ACSS2;SMPD1;ACAT1 17905:[DB14011 DB11639] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;BMPR2;BMPR1A GO:0030324| lung development CYP1A2;BMPR1A GO:0042127| regulation of cell proliferation PTGS1;PTGS2;BMPR2 GO:0030308| negative regulation of cell growth BMPR2;PPARG GO:0061298| retina vasculature development in camera-type eye CYP1B1;BMPR2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;BMPR1A GO:0007420| brain development BMPR2;ACAT1 GO:0007399| nervous system development SMPD1;GLRB;BMPR1A GO:0007507| heart development BMPR1A;PPARG GO:0006955| immune response CNR2;OPRD1;BMPR1A 17906:[DB14011 DB11075] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11075|Hypromellose EPCAM common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;EPCAM GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EPCAM;PPARG GO:0001657| ureteric bud development CAT;EPCAM 17907:[DB14011 DB00385] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00385|Valrubicin TOP2A common genes common pathways GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;TOP2A;SMPD1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG 17908:[DB14011 DB14596] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0036378| CYP3A4 GO:0006915| apoptotic process VDAC1;GPX1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;TRPV1;TRPV4;PPARG GO:0008203| cholesterol metabolic process HMGCR;PON1;CAT GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0019372| lipoxygenase pathway ALOX15;PON1;PTGS2;ALOX5;GPX1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1A1;CYP2C9;CRYZ GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;NR3C1;OPRD1;CHRNA7 GO:0070542| response to fatty acid CAT;PON1;PTGS2 GO:0009636| response to toxin PON1;GPX1;CAT;CYP1A1;CYP1B1 GO:0046470| phosphatidylcholine metabolic process PON1;PLA2G1B GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PON1;PTGS2;CYP1A2;HMGCR;NAAA;PTGS1;GPX1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0031667| response to nutrient levels SOD1;PON1 GO:0008209| androgen metabolic process CYP3A4 17909:[DB14011 DB00920] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00920|Ketotifen HRH1;PGD common genes common pathways GO:0007613| memory HRH1;PTGS2;CNR1;HTR2A;CHRNA7 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1;HTR2A GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;HRH1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ALOX5;PTGS1;CNR2;PTGS2;HRH1 GO:0008542| visual learning HMGCR;HRH1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;HRH1;OPRM1;CNR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;HTR2A GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;PGD;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR 17910:[DB14011 DB04207] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04207|N-(5-Amino-5-Carboxypentyl)Glutamic Acid AASS common genes common pathways GO:0008152| metabolic process AASS;SMPD1;ACAT1 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP2C9;CYP1A1;AASS;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0051262| protein tetramerization HMGCR;CAT;AASS 17911:[DB14011 DB07105] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07105|2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE F2 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 17912:[DB14011 DB13036] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13036|Ramatroban PTGDR2 common genes common pathways GO:0007218| neuropeptide signaling pathway PTGDR2;OPRM1;OPRD1;GLRA3;GLRB;GLRA1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGDR2;CNR1;OPRD1;CNR2;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;PTGDR2;GPR18;PPARG GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;PTGDR2;HTR2A;GLRA3;OPRD1;OPRM1 GO:0006955| immune response PTGDR2;OPRD1;CNR2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway PTGDR2;OPRM1;OPRD1 GO:0007165| signal transduction CHRNA7;PTGDR2;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 17913:[DB14011 DB14530] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14530|Chromous sulfate CYB5A;TF common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYB5A;CYP3A7;PTGS2 GO:0022900| electron transport chain IDO1;GSR;CYB5A;CYP1A2 GO:0002576| platelet degranulation SOD1;TF GO:0046686| response to cadmium ion CAT;CYB5A GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;TF GO:0001895| retina homeostasis SOD1;TF GO:0006811| ion transport TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;TF;CACNA1H 17914:[DB14011 DB01144] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 GO:0001822| kidney development CA2;CAT GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;CA3;SOD1;PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG;CA2 GO:0045471| response to ethanol CA3;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 17915:[DB14011 DB00558] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00558|Zanamivir NEU2 common genes common pathways GO:0006687| glycosphingolipid metabolic process SMPD1;NEU2 GO:0016042| lipid catabolic process NAPEPLD;NEU2;DAGLA;PLA2G1B GO:0008152| metabolic process SMPD1;NEU2;ACAT1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;NEU2;NAAA;GPX1;PTGS1;PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B 17916:[DB14011 DB00033] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNGR2 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;IFNGR1 GO:0009615| response to virus IFNGR2;CYP1A1;IFNGR1 17917:[DB14011 DB08168] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways GO:0006915| apoptotic process VDAC1;PPIF;GPX1 GO:0006979| response to oxidative stress PTGS1;GPX1;PPIF;CAT;PTGS2;SOD1 GO:0006355| regulation of transcription, DNA-dependent HDAC8;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;HDAC8 GO:0043066| negative regulation of apoptotic process GPX1;PPIF;CAT;HMGCR;PTGS2;SOD1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;PPIF GO:0090201| negative regulation of release of cytochrome c from mitochondria PPIF;GPX1 GO:0010629| negative regulation of gene expression HDAC8;OPRD1 GO:0071277| cellular response to calcium ion ALOX15;PPIF GO:0006351| transcription, DNA-dependent HDAC8;PPARG 17918:[DB14011 DB13997] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A3;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0042391| regulation of membrane potential ABCB5;CACNA1H;GLRB;CACNA1G;GLRA1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0036378| CYP3A4 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;ABCB5;CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8 GO:0002933| CYP3A7;CYP3A4;CYP3A5;CYP1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0055114| oxidation-reduction process CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB5 GO:0006855| drug transmembrane transport ABCB5;ABCC1;ABCG2 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0008152| metabolic process SMPD1;ACAT1;UGT1A3 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 17919:[DB14011 DB03958] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03958|7-methyl-guanosine-5'-triphosphate-5'-guanosine DCPS common genes common pathways 17920:[DB14011 DB08044] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08044|ABT-341 DPP4 common genes common pathways GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0001666| response to hypoxia DPP4;CYP1A1;CHRNA7;CAT GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 17921:[DB14011 DB14582] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0006954| inflammatory response ORM1;IDO1;ALOX15;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0098869| PTGS2;CAT;PTGS1;GPX1;ALB;GSR GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;ORM1;GPR18 GO:0043312| neutrophil degranulation CAT;ALOX5;ORM1;ORM2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0002576| platelet degranulation ALB;ORM1;ORM2;SOD1 17922:[DB14011 DB00691] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0006811| ion transport TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1G;SLC15A1;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;SLC15A2 GO:0008217| regulation of blood pressure PPARG;PTGS1;ACE;PTGS2;SOD1 GO:0046718| entry of virus into host cell ACE2;HTR2A GO:0060047| heart contraction GPX1;ACE;SOD1 GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0016032| viral reproduction VDAC1;HTR2A;ACE2 GO:0050727| regulation of inflammatory response PTGS2;ACE2 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC15A2;TRPV2;ABCC1;CACNA1G;TRPA1;SLC15A1;VDAC1;TRPV4;CACNA1I;TRPV1;TRPM8;ABCG2 GO:0007283| spermatogenesis ACE;SOD1;CNR1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0006810| transport TRPV2;SLC15A2;ABCG2;TRPV1;CACNA1I;SLC15A1;ABCC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ACE2 GO:0001822| kidney development ACE;CAT 17923:[DB14011 DB02322] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;CCL5;PTGS2 GO:0070234| positive regulation of T cell apoptosis IDO1;CCL5 GO:0071407| cellular response to organic cyclic compound CCL5;CYP1A1;CYP1B1 GO:0030593| neutrophil chemotaxis CCL5;PLA2G1B GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;CCL5 GO:0009615| response to virus CYP1A1;CCL5 GO:0034097| response to cytokine stimulus AANAT;CCL5;PTGS2 GO:0051262| protein tetramerization CAT;HMGCR;CCL5 GO:0071356| cellular response to tumor necrosis factor CCL5;TRPV1 GO:0034612| response to tumor necrosis factor PTGS2;CCL5 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;CCL5;HMGCR;GPR55;HTR2A GO:1901214| CHRNA7;CCL5 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CHRNA7;CCL5;HTR2A;GPR12 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;CCL5;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PPARG;GPR18 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CCL5;CAT GO:0006955| immune response OPRD1;CCL5;CNR2 GO:0006816| calcium ion transport TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;TRPV3;CCL5;CACNA1H GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;CCL5;TRPV1;ALOX15;IDO1 GO:0010759| positive regulation of macrophage chemotaxis TRPV4;CCL5 GO:0009636| response to toxin CYP1A1;CYP1B1;CCL5;GPX1;CAT GO:0070233| negative regulation of T cell apoptosis CCL5;IDO1 GO:0050796| regulation of insulin secretion CCL5;CNR1 17924:[DB14011 DB05442] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process IL1B;TRPV1;PTGS2;OPRM1 GO:0045766| positive regulation of angiogenesis CYP1B1;IL1B;CHRNA7 GO:0000187| activation of MAPK activity PLA2G1B;IL1B;SOD1;CHRNA7 GO:0006915| apoptotic process VDAC1;IL1B;GPX1 GO:0010628| positive regulation of gene expression IL1B;TRPV4 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;IL1B GO:0032496| response to lipopolysaccharide CYP1A1;IL1B;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0001660| fever generation TRPV1;IL1B GO:0071639| positive regulation of monocyte chemotactic protein-1 production IL1B;TRPV4 GO:0046330| positive regulation of JNK cascade TRPV4;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;IL1B GO:0030593| neutrophil chemotaxis PLA2G1B;IL1B GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IL1B GO:0071407| cellular response to organic cyclic compound CYP1A1;IL1B;CYP1B1 GO:0007566| embryo implantation IL1B;PTGS2;SOD1 GO:0050796| regulation of insulin secretion IL1B;CNR1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;IL1B GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;IL1B GO:0051781| positive regulation of cell division IL1B;CAT GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;IL1B;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1;IL1B GO:0031622| positive regulation of fever generation CNR1;PTGS2;IL1B GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;IL1B GO:0006954| inflammatory response TRPV1;IL1B;IDO1;ALOX15;PTGS2;CNR2;ALOX5;PTGS1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IL1B;PLA2G1B GO:0006955| immune response OPRD1;CNR2;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;PPARG GO:2000778| positive regulation of interleukin-6 secretion IL1B;TRPV4 17925:[DB14011 DB03864] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03864|Monothioglycerol PREP common genes common pathways 17926:[DB14011 DB09060] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;ABCC2 GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;CYP1A1;ABCC2;IDO1 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0055085| transmembrane transport SLC22A8;CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;ABCC2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4 GO:0006979| response to oxidative stress ABCC2;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0006810| transport TRPV2;ABCC1;ABCC2;ABCG2;TRPV1;CACNA1I GO:0009408| response to heat TRPV1;ABCC2;TRPV3;SOD1;TRPV2 GO:0007565| female pregnancy IDO1;ABCC2 GO:0098656| SLC22A8;VDAC1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;SLC22A8;TRPV2;CHRNA7 GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCC1 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H 17927:[DB14011 DB04733] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways GO:0046716| muscle cell homeostasis SOD1;ALDOA GO:0043312| neutrophil degranulation ALOX5;CAT;ALDOA GO:0002576| platelet degranulation ALDOA;SOD1 GO:0007015| actin filament organization ALDOA;PLA2G1B;TRPV4 GO:0051289| protein homotetramerization CAT;TRPV1;TRPM8;ALDOA;CRYZ;TRPA1 17928:[DB14011 DB08594] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08594|TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE CTSK common genes common pathways GO:1903146| VDAC1;CTSK GO:0045453| bone resorption CTSK;GPR55 17929:[DB14011 DB04114] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0008283| cell proliferation ACHE;HTR1A;GPX1;CYP1A1 17930:[DB14011 DB04008] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04008|Bis(5-Amidino-Benzimidazolyl)Methane Zinc PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 17931:[DB14011 DB01599] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01599|Probucol ABCA1;CES1 common genes common pathways GO:0010887| negative regulation of cholesterol storage PPARG;ABCA1 GO:0098656| ABCA1;VDAC1 GO:0007584| response to nutrient PPARG;CNR1;HMGCR;ABCA1 GO:0009636| response to toxin CES1;GPX1;CAT;CYP1A1;CYP1B1 GO:0010745| negative regulation of macrophage derived foam cell differentiation ABCA1;PPARG GO:0045332| phospholipid translocation ABCA1;ABCC1 GO:0019216| regulation of lipid metabolic process CNR1;ABCA1;HMGCR;PPARG;CYP1A1 GO:0002790| peptide secretion TRPV1;ABCA1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;CES1;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0008152| metabolic process SMPD1;CES1;ACAT1 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP1A2;PTGS2;ABCA1;HMGCR;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0030855| epithelial cell differentiation CES1;PPARG;VDAC1 GO:0055085| transmembrane transport CACNA1H;TRPV3;ABCA1;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;ABCA1;CYP3A7;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;ABCA1;OPRD1 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;ABCA1 GO:0042493| response to drug CAT;HTR2A;SOD1;ABCA1;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0071300| cellular response to retinoic acid PPARG;ABCA1 GO:0008203| cholesterol metabolic process CAT;ABCA1;HMGCR GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0033344| cholesterol efflux ABCG2;ABCA1 17932:[DB14011 DB04559] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04559|N-(Chlorophenyl)-N'-Hydroxyguanidine NOS3 common genes common pathways GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;NOS3;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;GPX1;ALOX5;PTGS1 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0042311| vasodilation GPX1;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development CYP1A2;NOS3 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;NOS3;PPARG GO:1902042| NOS3;GPX1 GO:0006809| nitric oxide biosynthetic process NOS3;CYP1B1 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0045454| cell redox homeostasis GPX1;NOS3;GSR GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;NOS3 GO:0045776| negative regulation of blood pressure NOS3;CNR1 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 17933:[DB14011 DB09258] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways GO:0007595| lactation SLC29A1;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0007584| response to nutrient PPARG;HMGCR;SERPINC1;CNR1 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0007283| spermatogenesis SERPINA5;CNR1;SOD1 17934:[DB14011 DB02485] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 17935:[DB14011 DB08153] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08153|(5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE HSP90AB1 common genes common pathways GO:0043524| negative regulation of neuron apoptosis HSP90AB1;SOD1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;HSP90AB1 GO:0001890| placenta development PPARG;HSP90AB1;SOD1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;HSP90AB1 GO:0042493| response to drug SMPD1;HSP90AB1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0043066| negative regulation of apoptotic process HSP90AB1;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0043312| neutrophil degranulation HSP90AB1;CAT;ALOX5 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG;HSP90AB1 GO:0042220| response to cocaine HSP90AB1;SMPD1;OPRM1;CNR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HSP90AB1 17936:[DB14011 DB03370] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03370|FR239087 ADA common genes common pathways GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;GPX1;ADA GO:0001889| liver development ACAT1;ADA;CYP1A1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0001890| placenta development PPARG;ADA;SOD1 GO:0043066| negative regulation of apoptotic process GPX1;ADA;CAT;PTGS2;HMGCR;SOD1 GO:0007155| cell adhesion ADA;CYP1B1 GO:0033197| response to vitamin E CAT;ADA GO:0030324| lung development CYP1A2;ADA GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0043278| response to morphine ADA;OPRM1;CNR1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT;ADA GO:0007568| aging CYP1A1;ADA;CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD GO:0001666| response to hypoxia CHRNA7;CAT;ADA;CYP1A1 17937:[DB14011 DB04250] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04250|Butyrylthiocholine BCHE;BCHE common genes common pathways GO:0007612| learning PTGS2;VDAC1;BCHE GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;BCHE;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;BCHE;PPARG 17938:[DB14011 DB05936] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05936|CVT-6883 ADORA2B common genes common pathways GO:0000187| activation of MAPK activity ADORA2B;PLA2G1B;CHRNA7;SOD1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;GPR18;PPARG;ADORA2B GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA2B GO:0007165| signal transduction GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;ADORA2B;PLA2G1B;CACNA1I GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1;ADORA2B 17939:[DB14011 DB08426] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08426|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 17940:[DB14011 DB03305] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03305|N5-Iminoethyl-L-Ornithine NOS3 common genes common pathways GO:0042311| vasodilation GPX1;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development CYP1A2;NOS3 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;NOS3;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;GPX1;ALOX5;PTGS1 GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 GO:0001525| angiogenesis PTGS2;CYP1B1;NOS3 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0009408| response to heat SOD1;TRPV3;TRPV2;NOS3;TRPV1 GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;NOS3;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;NOS3;CYP1B1;PPARG GO:1902042| GPX1;NOS3 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0006809| nitric oxide biosynthetic process NOS3;CYP1B1 17941:[DB14011 DB01736] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01736|[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium SLC25A4 common genes common pathways GO:0050796| regulation of insulin secretion CNR1;SLC25A4 GO:0016032| viral reproduction VDAC1;SLC25A4;HTR2A GO:0006810| transport ABCC1;SLC25A4;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;SLC25A4;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;CACNA1H;TRPV3;TRPV2 17942:[DB14011 DB03604] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03604|Tiratricol THRB common genes common pathways GO:0043401| steroid hormone mediated signaling pathway THRB;PPARG GO:0006351| transcription, DNA-dependent THRB;PPARG GO:0008016| regulation of heart contraction THRB;CACNA1H GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;THRB GO:0007605| sensory perception of sound THRB;SOD1;GPX1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter THRB;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;THRB;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent THRB;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;THRB 17943:[DB14011 DB00132] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00132|Alpha-Linolenic Acid FADS1;FADS2;SLC8A1;TRPV1;ELOVL4;PPARA;NR1H4;PPARD;PPARG;RXRA;FABP7 common genes PPARG;TRPV1 common pathways GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0042593| glucose homeostasis NR1H4;CNR1;PPARG;TRPV4 GO:0002376| immune system process IDO1;NR1H4 GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7;NR1H4 GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;SLC8A1;CHRNA7;TRPV4;TRPM8 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0006936| muscle contraction GLRA1;SLC8A1;CACNA1H GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0071456| cellular response to hypoxia SLC8A1;SLC29A1;PTGS2;OPRD1;PPARD GO:0015909| long-chain fatty acid transport PPARG GO:0007635| chemosensory behavior TRPV1 GO:0046697| decidualization PPARD;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0006810| transport TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;TRPV1 GO:0071468| cellular response to acidity TRPV1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0048511| rhythmic process PPARG;PPARA;AANAT GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0031000| response to caffeine PPARG GO:0015758| glucose transport PPARD;PLA2G1B GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CYP1A1;SLC8A1;CAT;CHRNA7;PPARA GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;CACNA1H;TRPV3;SLC8A1;TRPV2 GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0006915| apoptotic process GPX1;PPARD;VDAC1 GO:0007043| cell-cell junction assembly TRPV4;NR1H4 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0071502| cellular response to temperature stimulus TRPV1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;NR1H4;PPARD;TRPV4;TRPV1;RXRA;PPARG GO:0045087| innate immune response PPARG;NR1H4 GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress PPARG;CYP1A1;SLC8A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;NR1H4;PLA2G1B;PPARG;RXRA GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;PPARD;HTR1A;HTR2A GO:0071300| cellular response to retinoic acid PPARG GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;NR1H4;HMGCR;PPARD;CAT;GPX1 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;GLRA1;TRPV1;GLRB GO:0032526| response to retinoic acid PPARG;RXRA GO:0002024| diet induced thermogenesis TRPV4;TRPV1 GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0051481| reduction of cytosolic calcium ion concentration SLC8A1;OPRM1 GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0070509| calcium ion import SLC8A1;CACNA1H;CACNA1I;TRPV4;CACNA1G GO:0001660| fever generation TRPV1 GO:0042127| regulation of cell proliferation PPARD;PTGS2;PTGS1 GO:0042060| wound healing PPARA;OPRM1;PPARD;ALOX15 GO:0008203| cholesterol metabolic process RXRA;PPARD;HMGCR;CAT GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter RXRA;PPARG;NR1H4;PPARD;PPARA GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0016525| negative regulation of angiogenesis PPARG GO:0048265| response to pain TRPA1;TRPV1 GO:0033189| response to vitamin A PPARG;CYP1A1;PPARD;CAT GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0071455| cellular response to hyperoxia PPARG GO:0050728| negative regulation of inflammatory response CNR2;NR1H4;PPARD;PPARA GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0030224| monocyte differentiation PPARG GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPA1;TRPV1 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;FADS2;CYP1B1;CYP2C9;CYP1A1;FADS1;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:0042493| response to drug CAT;SLC8A1;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0006355| regulation of transcription, DNA-dependent RXRA;FADS1;PPARG;NR1H4;PPARD;PPARA GO:0006631| fatty acid metabolic process FADS1;ALOX15;ELOVL4;FADS2;PPARA;PTGS2;PTGS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;PPARA;RXRA;PPARG GO:0006633| fatty acid biosynthetic process ELOVL4;FADS2;PLA2G1B;FADS1;PTGS1;PTGS2 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;NR1H4;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0065009| regulation of molecular function TRPV1 GO:0070588| calcium ion transmembrane transport SLC8A1;TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0007204| elevation of cytosolic calcium ion concentration SLC8A1;OPRM1;HTR2A;TRPV1;TRPV4 GO:0022008| neurogenesis FABP7;DAGLA GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;FADS1;RXRA;HMGCR;PPARA;CNR1 GO:0007566| embryo implantation SOD1;PTGS2;PPARD;RXRA GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;SLC8A1;HMGCR;CNR1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;FABP7;CYP1B1;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0014823| response to activity PPARD;CAT GO:0045600| positive regulation of fat cell differentiation PPARG;PPARD;HTR2A GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0001890| placenta development PPARG;RXRA;PPARD;SOD1 GO:0060612| adipose tissue development PPARD;ACAT1 GO:0019395| fatty acid oxidation PPARG;PPARD GO:0055088| lipid homeostasis PPARG GO:0032868| response to insulin stimulus TRPV4;PPARA;AANAT;CAT GO:0006811| ion transport TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;SLC8A1;GLRA3;TRPV3;CACNA1H GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;NR1H4;CAT GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;PPARD GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;ACAT1;AANAT GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:1990090| TRPV1 GO:0007507| heart development PPARG;RXRA;PPARA;PPARD GO:0007399| nervous system development GLRB;SMPD1;FABP7 GO:0002027| regulation of heart rate SLC8A1;CACNA1G GO:0045165| cell fate commitment PPARG GO:0060078| regulation of postsynaptic membrane potential CHRNA7;SLC8A1 GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;FADS1;ALOX15;ELOVL4;CYP2D6;DAGLA;FADS2;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;PPARA;PTGS2;CYP1A2;PPARD;HMGCR;NAAA;PTGS1;GPX1 GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0050955| thermoception TRPA1;TRPM8;TRPV1 GO:0071312| cellular response to alkaloid TRPV1 GO:0001659| temperature homeostasis TRPV1;GPX1;HTR2A GO:0042542| response to hydrogen peroxide TRPA1;CAT;SLC8A1;GPX1;SOD1 GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0048469| cell maturation PPARG GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1 GO:0035725| sodium ion transmembrane transport CACNA1H;SLC8A1;CACNA1G;CACNA1I GO:0043401| steroid hormone mediated signaling pathway PPARA;NR1H4;PPARD;PPARG;RXRA GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0006351| transcription, DNA-dependent PPARD;NR1H4;PPARA;RXRA;PPARG GO:1901594| TRPV1 GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPA1;TRPV1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;NR1H4;PPARG;RXRA GO:0001774| microglial cell activation TRPV1 GO:0048266| behavioral response to pain TRPV1 GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0051924| regulation of calcium ion transport OPRD1;SLC8A1 GO:0002790| peptide secretion TRPV1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0050872| white fat cell differentiation PPARG GO:0009268| response to pH TRPV1 GO:1904706| PPARG GO:0014047| glutamate secretion TRPV1 GO:0051289| protein homotetramerization CRYZ;RXRA;TRPA1;TRPM8;TRPV1;CAT GO:0009408| response to heat TRPV2;SOD1;TRPV3;TRPV1 GO:0006954| inflammatory response CNR2;PTGS2;NR1H4;ALOX5;PTGS1;ALOX15;IDO1;TRPV1 GO:0016032| viral reproduction HTR2A;RXRA;VDAC1 GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1;TRPV3;CACNA1H;CHRNA7;SLC8A1;TRPV2 GO:0001964| startle response FABP7;GLRB;GLRA1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0098703| TRPV1 GO:0071320| cellular response to cAMP SLC8A1;AANAT GO:0071379| cellular response to prostaglandin stimulus PPARG 17944:[DB14011 DB06969] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06969|2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide HSP90AA1 common genes common pathways GO:0009409| response to cold TRPM8;TRPA1;HSP90AA1;PPARG GO:0009408| response to heat TRPV3;SOD1;TRPV2;HSP90AA1;TRPV1 GO:0007165| signal transduction HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;HSP90AA1;SMPD1;CACNA1I;PLA2G1B GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;OPRM1;PTGS2 17945:[DB14011 DB03129] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03129|[3-(1,3,2-Dioxaborolan-2-Yloxy)Propyl]Guanidine PRSS3 common genes common pathways GO:0043312| neutrophil degranulation PRSS3;ALOX5;CAT GO:0043542| endothelial cell migration CYP1B1;PRSS3 GO:0009235| cobalamin metabolic process ABCC1;PRSS3 17946:[DB14011 DB01005] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01005|Hydroxyurea RRM1;CYP2D6 common genes CYP2D6 common pathways GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0008152| metabolic process ACAT1;SMPD1;RRM1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0015949| nucleobase-containing small molecule interconversion RRM1;GSR GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;RRM1;CRYZ;CYP1A1;CYP2C9 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;CYP2D6;DAGLA;ALOX15;CYP1B1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 17947:[DB14011 DB04672] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways 17948:[DB14011 DB06140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06140|SUVN-502 HTR6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR6;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;OPRM1;CNR2;HTR6 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;GLRA3;CACNA1G;GLRA1;VDAC1;GLRB;HTR6 GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;HTR6;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 17949:[DB14011 DB00702] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00702|Icodextrin AMY2A common genes common pathways GO:0008152| metabolic process ACAT1;AMY2A;SMPD1 17950:[DB14011 DB01425] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01425|Alizapride DRD2 common genes common pathways GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;DRD2;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0035094| response to nicotine CNR1;CHRNA7;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0043278| response to morphine DRD2;OPRM1;CNR1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential DRD2;GLRB;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0007628| adult walking behavior GLRA1;DRD2;GLRB GO:0007626| locomotory behavior SOD1;OPRM1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;PPARG GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0042220| response to cocaine OPRM1;CNR1;DRD2;SMPD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;DRD2;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;DRD2;GPR18 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0009416| response to light stimulus DRD2;AANAT GO:0001666| response to hypoxia CYP1A1;DRD2;CAT;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway DRD2;PPARG;GPR18;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0051209| release of sequestered calcium ion into cytosol DRD2;TRPV1;TRPA1;HTR2A GO:0006874| cellular calcium ion homeostasis DRD2;TRPV4;TRPM8;GPR12;HTR2A;CHRNA7 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0008542| visual learning DRD2;HMGCR GO:0001964| startle response GLRA1;GLRB;DRD2 GO:0048678| response to axon injury SOD1;DRD2 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CAT;DRD2 GO:0045776| negative regulation of blood pressure DRD2;CNR1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0048148| behavioral response to cocaine HTR2A;DRD2 GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0001659| temperature homeostasis HTR2A;GPX1;DRD2;TRPV1 GO:0014854| response to inactivity CAT;DRD2 GO:0009636| response to toxin GPX1;CAT;CYP1A1;DRD2;CYP1B1 GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;DRD2;CYP1B1 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0001975| response to amphetamine SOD1;CNR2;DRD2 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;DRD2;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0050482| arachidonic acid secretion DRD2;PLA2G1B GO:1900273| CHRNA7;DRD2 17951:[DB14011 DB01057] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01057|Echothiophate BCHE;ALB common genes common pathways GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;BCHE;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ALB GO:0001895| retina homeostasis SOD1;ALB GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;BCHE;CYP1B1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE 17952:[DB14011 DB01998] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;SERPINA1;CAT GO:0002576| platelet degranulation SERPINA1;SOD1 17953:[DB14011 DB13168] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes PTGS2;ALOX5 common pathways GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;FADS2;PLA2G1B;FADS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;FADS1;HMGCR;CNR1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0033280| response to vitamin D PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;FADS2;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;FADS1 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0050727| regulation of inflammatory response PTGS2 GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1;TRPA1;TRPV1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;IDO1;ALOX15;TRPV1 GO:0010942| positive regulation of cell death PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0098869| GSR;GPX1;PTGS1;CAT;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0007568| aging CYP1A1;CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:2001300| ALOX5 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0043312| neutrophil degranulation ALOX5;CAT GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP1B1;FADS2;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;FADS1;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0006631| fatty acid metabolic process FADS1;ALOX15;FADS2;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006355| regulation of transcription, DNA-dependent FADS1;PPARG GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 17954:[DB14011 DB03066] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;SLC16A1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1A1;CYP1B1 GO:0032094| response to food CYP1A1;SLC16A1;OPRM1 GO:0042593| glucose homeostasis CNR1;SLC16A1;PPARG;TRPV4 GO:0055085| transmembrane transport SLC16A7;CACNA1H;TRPV3;SLC16A1;TRPV2;TRPA1;SLC16A3;CACNA1G;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1 17955:[DB14011 DB11892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11892|Prulifloxacin CYP1A2 common genes CYP1A2 common pathways GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP2C9;CYP1A1;CRYZ GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;CYP1A1;IDO1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;NAAA;PTGS1;GPX1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 17956:[DB14011 DB06756] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCL2;PPARG;BCHE;CYP1B1 GO:0001662| behavioral fear response VDAC1;HTR1A;BCL2 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0030336| negative regulation of cell migration CYP1B1;BCL2 GO:0009791| post-embryonic development CYP1A2;BCL2 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;BCL2 GO:0009636| response to toxin BCL2;CAT;GPX1;CYP1A1;CYP1B1 GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;VDAC1 GO:0008283| cell proliferation HTR1A;BCL2;GPX1;CYP1A1 GO:0010332| response to gamma radiation BCL2;GPX1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;OPRD1;PTGS2 GO:0072593| reactive oxygen species metabolic process SOD1;BCL2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2;BCL2 GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0010942| positive regulation of cell death PRODH;PTGS2 GO:0030217| T cell differentiation BCL2;GPR18 GO:0007565| female pregnancy IDO1;BCL2 GO:0008631| induction of apoptosis by oxidative stress BCL2;GPX1;CYP1B1;PRODH GO:0043524| negative regulation of neuron apoptosis SOD1;BCL2 GO:0001503| ossification ALOX15;BCL2 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;CAT;BCL2;SOD1 GO:0009314| response to radiation PTGS2;OPRM1;BCL2;CAT GO:0001657| ureteric bud development BCL2;CAT GO:0006915| apoptotic process GPX1;BCL2;VDAC1 GO:0001541| ovarian follicle development SOD1;BCL2 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;CACNA1I;TRPV4;VDAC1;TRPV3;BCL2;CACNA1H;TRPV2 GO:0043085| positive regulation of catalytic activity BCL2;SOD1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;BCL2;PTGS2;SOD1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;BCL2;GPR12;HTR2A;CHRNA7 GO:0048538| thymus development SOD1;BCL2 GO:0071456| cellular response to hypoxia PTGS2;BCL2;OPRD1;SLC29A1 GO:0010468| regulation of gene expression BCL2;CYP1A2 GO:0007015| actin filament organization BCL2;PLA2G1B;TRPV4 GO:0035094| response to nicotine CHRNA7;CNR1;BCL2 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PRODH;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0007569| cell aging BCL2;SOD1 GO:0042493| response to drug CAT;HTR2A;SOD1;BCL2;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;BCHE GO:0034097| response to cytokine stimulus BCL2;PTGS2;AANAT GO:0001822| kidney development CAT;BCL2 GO:0043066| negative regulation of apoptotic process PTGS2;BCL2;HMGCR;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;BCL2;HMGCR;HTR1A;HTR2A GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0007612| learning BCHE;VDAC1;PTGS2 17957:[DB14011 DB07389] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;NOS2;CYP2C9;CYP1A1 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;NOS2;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;NOS2 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0045454| cell redox homeostasis GPX1;GSR;NOS2 GO:0050796| regulation of insulin secretion CNR1;NOS2 17958:[DB14011 DB03073] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03073|3-Methoxybenzamide PARP1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;PARP1 GO:0034599| cellular response to oxidative stress SOD1;PARP1;CAT;GPX1;GSR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PARP1 GO:0006915| apoptotic process VDAC1;GPX1;PARP1 GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0071294| cellular response to zinc ion GLRA1;PARP1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PARP1 GO:0010332| response to gamma radiation GPX1;PARP1 17959:[DB14011 DB03009] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03009|2-[(2-Oxo-2-Piperidin-1-Ylethyl)Thio]-6-(Trifluoromethyl)Pyrimidin-4(1h)-One FABP4 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;FABP4 GO:0071356| cellular response to tumor necrosis factor FABP4;TRPV1 GO:0050872| white fat cell differentiation PPARG;FABP4 GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0050729| positive regulation of inflammatory response TRPV4;FABP4 17960:[DB14011 DB00787] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways GO:0006811| ion transport TRPV3;CACNA1H;SLC22A8;GLRA3;TRPV2;CHRNA7;SLC22A1;CACNA1G;GLRA1;TRPA1;SLC10A2;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC22A8 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A1;SLC47A2;SLC47A1 GO:0006812| cation transport SLC22A1;TRPM8 GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0006810| transport TRPV2;ABCG2;SLC10A2;CACNA1I;TRPV1;ABCC1 GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A1;SLC22A6 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0055085| transmembrane transport SLC47A2;SLC47A1;TRPV2;SLC22A8;TRPV3;CACNA1H;TRPM8;ABCG2;SLC10A2;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;ABCC1;SLC22A1;CACNA1G;SLC22A6 17961:[DB14011 DB09332] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;POR;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0022900| electron transport chain GSR;IDO1;POR;CYP1A2 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;POR;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP3A7;PTGS2;VKORC1;CYP1A2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT GO:0050728| negative regulation of inflammatory response CNR2;PROC GO:0051897| positive regulation of protein kinase B signaling cascade F10;F7;GPX1 GO:0007623| circadian rhythm AANAT;F7 GO:0009812| flavonoid metabolic process POR;CYP1A1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;F2 GO:0002576| platelet degranulation PROS1;SOD1 GO:0043066| negative regulation of apoptotic process POR;SOD1;PTGS2;HMGCR;CAT;GPX1;PROC GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;F7 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;F7 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0031100| organ regeneration PPARG;F7 GO:0017144| drug metabolic process CYP3A4;VKORC1;CYP1A2;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0031667| response to nutrient levels F7;SOD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process POR;PTGS2;GPX1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001889| liver development CYP1A1;PROC;ACAT1 GO:0070988| demethylation CYP1A1;POR GO:0006805| xenobiotic metabolic process POR;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;F7;TRPA1;CYP1A1;PPARG GO:0019395| fatty acid oxidation POR;PPARG GO:0061844| F2;PLA2G1B GO:0007584| response to nutrient PPARG;POR;HMGCR;CNR1 GO:0043627| response to estrogen stimulus F7;PPARG GO:0009725| response to hormone stimulus F7;ACAT1 17962:[DB14011 DB01750] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01750|1-naphthaleneacetic acid SKP1 common genes common pathways GO:0006879| cellular iron ion homeostasis SKP1;SOD1;ABCG2 17963:[DB14011 DB02596] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02596|Alpha,Beta-Methyleneadenosine-5'-Triphosphate folK;panC;nadE;NMNAT3;carA common genes common pathways GO:0009611| response to wounding GPX1;NMNAT3;CYP1A1 17964:[DB14011 DB07143] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07143|D-phenylalanyl-N-benzyl-L-prolinamide F2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0061844| F2;PLA2G1B 17965:[DB14011 DB05327] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05327|Ranirestat AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0055114| oxidation-reduction process CRYZ;AKR1B1;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0022900| electron transport chain CYP1A2;AKR1B1;IDO1;GSR GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;AKR1B1 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0010033| response to organic substance PPARG;CYP1A1;AKR1B1;TRPA1;CYP1A2;PTGS2;SOD1 17966:[DB14011 DB00029] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0050714| positive regulation of protein secretion PLA2G1B;FGA GO:0045766| positive regulation of angiogenesis CYP1B1;SERPINE1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;FGA;TRPV4;ALOX15 GO:0043388| positive regulation of DNA binding PLAUR;PPARG GO:0002376| immune system process IDO1;FGA GO:0051702| interaction with symbiont PLG;GPX1 GO:0033629| negative regulation of cell adhesion mediated by integrin SERPINE1;CYP1B1 GO:0007623| circadian rhythm AANAT;SERPINE1 GO:0043066| negative regulation of apoptotic process PLAUR;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0002576| platelet degranulation SOD1;SERPINE1;PLG;FGA GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;PPARG;PLA2G1B GO:0043312| neutrophil degranulation ALOX5;CAT;PLAUR GO:0045087| innate immune response PPARG;FGA GO:0030336| negative regulation of cell migration CYP1B1;SERPINE1 GO:0008285| negative regulation of cell proliferation PLG;PPARG;CYP1B1;PTGS2;OPRM1 GO:1902042| FGA;GPX1;SERPINE1 GO:0050729| positive regulation of inflammatory response TRPV4;SERPINE1 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;FGA GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;FGA;PLAUR;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0034116| positive regulation of heterotypic cell-cell adhesion FGA;ALOX15 GO:0001934| positive regulation of protein phosphorylation PLAUR;CHRNA7 GO:0061045| negative regulation of wound healing HMGCR;SERPINE1 GO:0051592| response to calcium ion FGA;AANAT GO:0001525| angiogenesis CYP1B1;SERPINE1;PTGS2 17967:[DB14011 DB08051] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DPP4 17968:[DB14011 DB08127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CRABP2;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent CRABP2;PPARG 17969:[DB14011 DB03023] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC;LCK GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug LCK;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;LYN;TRPA1;SRC;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0043066| negative regulation of apoptotic process GPX1;SRC;CAT;PTGS2;HMGCR;SOD1 GO:0071300| cellular response to retinoic acid LYN;PPARG GO:0009615| response to virus SRC;CYP1A1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;LYN GO:0002576| platelet degranulation LYN;SOD1 GO:0045087| innate immune response LCK;LYN;PPARG;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2;LCK GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043407| negative regulation of MAP kinase activity LYN;SMPD1;HMGCR GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0043200| response to amino acid stimulus GLRA3;LYN;GLRB GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;SRC;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0002376| immune system process SRC;IDO1;LYN GO:0034605| cellular response to heat TRPV1;TRPV4;LYN;PTGS2 GO:0051209| release of sequestered calcium ion into cytosol LCK;TRPV1;TRPA1;HTR2A GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0016032| viral reproduction SRC;HTR2A;VDAC1;LCK;LYN GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;LYN;ALOX5;PTGS1;PTGS2;CNR2 GO:0030217| T cell differentiation LCK;GPR18 GO:0010976| positive regulation of neuron projection development CNR1;LYN GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;SRC;HTR2A GO:0031667| response to nutrient levels SRC;SOD1 GO:0001934| positive regulation of protein phosphorylation LYN;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0035556| intracellular signal transduction SRC;LYN;PLA2G1B GO:0042542| response to hydrogen peroxide CAT;SRC;GPX1;SOD1;TRPA1 GO:0050727| regulation of inflammatory response LYN;PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;SRC;CNR1;SOD1;PTGS2 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0048678| response to axon injury LYN;SOD1 GO:0008285| negative regulation of cell proliferation CYP1B1;LYN;PPARG;OPRM1;PTGS2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;LYN;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin CYP1A1;LYN;CYP1B1;GPX1;CAT GO:0006919| activation of caspase activity LCK;PPARG GO:0008283| cell proliferation HTR1A;GPX1;SRC;CYP1A1 GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4;LYN GO:0045453| bone resorption GPR55;SRC GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0009725| response to hormone stimulus LYN;ACAT1 GO:0007165| signal transduction GPR18;LYN;PPARG;SMPD1;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;SRC GO:0043434| response to peptide hormone stimulus TRPV1;LYN GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B 17970:[DB14011 DB02359] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02359|9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0007165| signal transduction PPARG;HSP90AA1;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0009409| response to cold TRPM8;TRPA1;HSP90AA1;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AA1;TRPV1 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT 17971:[DB14011 DB04930] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04930|Permethrin SCN1A;ESR1;NR1I2;CYP2B6;CYP3A4 common genes CYP3A4 common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0086010| CACNA1H;SCN1A;CACNA1G;CACNA1I GO:0042738| exogenous drug catabolic process CYP2C19;CYP2B6;NR1I2;CYP2C9;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;SCN1A;TRPA1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP2B6;NR1I2;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;ESR1 GO:0019228| regulation of action potential in neuron CACNA1H;SCN1A;CACNA1G;CACNA1I GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SCN1A;CACNA1H GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0006811| ion transport TRPV2;SCN1A;CHRNA7;TRPV3;CACNA1H;GLRA3;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;SCN1A;CACNA1H GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;ESR1;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;NR1I2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;ESR1;OPRM1 GO:0042908| xenobiotic transport ABCG2;NR1I2;ABCC1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG;ESR1 GO:0050884| neuromuscular process controlling posture SCN1A;GLRA1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP2B6;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1I2;PLA2G1B;ESR1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2B6;CYP1B1;CYP2C19;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV1;TRPV4;PPARG GO:0007628| adult walking behavior GLRB;GLRA1;SCN1A GO:0001508| regulation of action potential CACNA1G;GLRA1;SCN1A GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;SCN1A;GLRA3 GO:0086002| SCN1A;CACNA1G GO:0036378| CYP3A4 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2;SCN1A GO:0042391| regulation of membrane potential SCN1A;CACNA1H;GLRB;GLRA1;CACNA1G GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TRPV1 GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CAT;ESR1;CYP1A2;PTGS2 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP1A1;CYP2C9;NR1I2;CYP2B6 17972:[DB14011 DB00550] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes CYP1A1 common pathways GO:0070365| hepatocyte differentiation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 GO:0009624| response to nematode CYP1A1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;PTGS2;CYP1A2 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0043010| camera-type eye development CYP1A1 GO:0045907| positive regulation of vasoconstriction DBH;PTGS2;HTR2A GO:0032502| developmental process CYP1A1 GO:0007613| memory CHRNA7;DBH;PTGS2;HTR2A;CNR1 GO:0001975| response to amphetamine DBH;CNR2;SOD1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1 GO:1900087| CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0008542| visual learning DBH;HMGCR GO:0019430| removal of superoxide radicals SOD1;MPO GO:0060137| maternal process involved in parturition CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0048149| behavioral response to ethanol DBH;OPRM1 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;DBH;HTR2A;GLRA3;OPRM1;OPRD1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0070988| demethylation CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:0009692| ethylene metabolic process CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0042446| hormone biosynthetic process CYP17A1;TPO GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0042744| hydrogen peroxide catabolic process TPO;GPX1;MPO;CAT GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0010041| response to iron(III) ion CYP1A1 GO:0098869| TPO;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0006979| response to oxidative stress TPO;MPO;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0042593| glucose homeostasis CNR1;DBH;PPARG;TRPV4 GO:0007568| aging CYP1A1;MPO;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1 GO:0009611| response to wounding GPX1;CYP1A1 GO:0048265| response to pain TRPV1;TRPA1;DBH GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0009308| amine metabolic process CYP1A1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0055114| oxidation-reduction process CAT;DBH;ALOX5;MPO;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;TPO GO:0032094| response to food CYP1A1;OPRM1;MPO GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0043312| neutrophil degranulation MPO;ALOX5;CAT GO:0043066| negative regulation of apoptotic process CAT;GPX1;MPO;SOD1;HMGCR;PTGS2 GO:0009612| response to mechanical stimulus MPO;PPARG;TRPV4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0007626| locomotory behavior DBH;OPRM1;SOD1 GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide MPO;CNR2;PTGS2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;DBH 17973:[DB14011 DB07274] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07274|N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation KDR;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0045766| positive regulation of angiogenesis CHRNA7;KDR;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;KDR GO:0001525| angiogenesis KDR;CYP1B1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0016032| viral reproduction VDAC1;KDR;HTR2A 17974:[DB14011 DB07979] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07979|(2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID DAO common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;DAO;CYP2D6;CYP2C19;GSR;IDO1 17975:[DB14011 DB07827] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07827|4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13;ALOX15 17976:[DB14011 DB03344] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03344|Inositol-(1,3,4,5,6)-Pentakisphosphate CYTH3 common genes common pathways GO:0065009| regulation of molecular function CYTH3;TRPV1 17977:[DB14011 DB05130] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05130|INCB3284 CCR2 common genes common pathways GO:0016525| negative regulation of angiogenesis CCR2;PPARG GO:0006874| cellular calcium ion homeostasis CHRNA7;CCR2;GPR12;HTR2A;TRPM8;TRPV4 GO:0009611| response to wounding CYP1A1;GPX1;CCR2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;CCR2 GO:0016032| viral reproduction HTR2A;CCR2;VDAC1 GO:0006955| immune response CCR2;CNR2;OPRD1 GO:0006954| inflammatory response CNR2;PTGS2;CCR2;PTGS1;ALOX5;ALOX15;IDO1;TRPV1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;CCR2 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2;CCR2 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CCR2;CHRNA7 GO:0050729| positive regulation of inflammatory response TRPV4;CCR2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;CCR2;TRPV1;TRPV4 17978:[DB14011 DB07060] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07060|3-(INDOL-3-YL) LACTATE HAO1 common genes common pathways GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;HAO1;SOD1 GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;HAO1;SOD1;CYP3A4 17979:[DB14011 DB09052] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09052|Blinatumomab CD19;CD3D common genes common pathways GO:0002376| immune system process IDO1;CD3D GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;CD3D GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;CD19 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;CD3D;PPARG GO:0030217| T cell differentiation CD3D;GPR18 GO:0007166| cell surface receptor linked signaling pathway CD19;TRPV1;CD3D;TRPA1 17980:[DB14011 DB08834] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways GO:0007420| brain development SLC7A11;ACAT1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC7A11 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;SLCO1A2;CACNA1H;GLRA3;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0035094| response to nicotine CNR1;SLC7A11;CHRNA7 GO:0006979| response to oxidative stress PTGS2;SLC7A11;SOD1;GPX1;PTGS1;CAT GO:0055085| transmembrane transport CACNA1H;TRPV3;SLCO1A2;TRPV2;CACNA1G;ABCC1;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8 17981:[DB14011 DB07843] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07843|5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 17982:[DB14011 DB04697] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04697|TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE F2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 17983:[DB14011 DB03153] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways GO:0007626| locomotory behavior HPRT1;SOD1;OPRM1 GO:0001975| response to amphetamine HPRT1;CNR2;SOD1 GO:0051289| protein homotetramerization TRPM8;HPRT1;TRPV1;CRYZ;TRPA1;CAT 17984:[DB14011 DB12651] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12651|Bardoxolone CASP8 common genes common pathways GO:0045471| response to ethanol CASP8;OPRM1;HMGCR;SOD1;CNR1;CAT GO:0007166| cell surface receptor linked signaling pathway TRPA1;CASP8;TRPV1 GO:0009409| response to cold TRPA1;PPARG;TRPM8;CASP8 GO:0071260| cellular response to mechanical stimulus PTGS2;CASP8 GO:0016032| viral reproduction HTR2A;CASP8;VDAC1 GO:0006919| activation of caspase activity CASP8;PPARG GO:1902042| GPX1;CASP8 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CASP8;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0046677| response to antibiotic CASP8;CYP1A1;SOD1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;CASP8 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;CASP8 GO:0034612| response to tumor necrosis factor CASP8;PTGS2 GO:0006915| apoptotic process CASP8;VDAC1;GPX1 17985:[DB14011 DB00145] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes GLRA1;GLRB;GLRA3;GPR18 common pathways GO:0042391| regulation of membrane potential GRIN2A;CACNA1H;GLRB;CACNA1G;GRIN2C;GLRA1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1;GSS GO:0006936| muscle contraction CACNA1H;GLRA1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;AGXT2;TRPV1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 GO:0051260| protein homooligomerization GLRA1;ACAT1;GLRA3 GO:0031100| organ regeneration PPARG;BAAT GO:0006820| anion transport GLRA1;VDAC1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;GLYAT;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0009611| response to wounding GPX1;GRIN2A;GRIN2C;CYP1A1 GO:0006810| transport TRPV2;SLC6A9;SLC6A5;GRIN2A;TRPV1;CACNA1I;ABCG2;ABCC1;GRIN2C GO:0035025| positive regulation of Rho protein signal transduction GPR55;GPR18 GO:0007568| aging GSS;SLC32A1;CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1 GO:0097112| gamma-aminobutyric acid receptor clustering GLRB GO:0001666| response to hypoxia CHRNA7;CAT;ALAS2;CYP1A1 GO:0051262| protein tetramerization SHMT2;CAT;SHMT1;HMGCR GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1 GO:0051591| response to cAMP AGXT;AANAT GO:0034220| ion transmembrane transport GLRA1;TRPA1;GRIN3B;GLRB;TRPV1;GLRA3;CHRNA7;GLRA2 GO:0043200| response to amino acid stimulus GLRB;GSS;GLRA3 GO:0046686| response to cadmium ion GSS;CAT GO:0034612| response to tumor necrosis factor GSS;PTGS2 GO:0055085| transmembrane transport CACNA1H;SLC16A10;TRPV3;SLC36A1;TRPV2;SLC6A9;SLC6A5;CACNA1G;ABCC1;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0032259| methylation GCSH;GNMT;CYP1A2 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;OPRD1;OPRM1;GLRA3;GLRA2 GO:0008284| positive regulation of cell proliferation SHMT2;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0007340| acrosome reaction GLRB;GLRA1 GO:0007628| adult walking behavior GLRB;GLRA1 GO:0009410| response to xenobiotic stimulus GPX1;GSS GO:0007611| learning or memory CNR1;GATM;CHRNA7;GRIN2A GO:0001508| regulation of action potential CACNA1G;GLRA1 GO:0007612| learning PTGS2;GRIN2A;VDAC1 GO:0007269| neurotransmitter secretion NAAA;SLC32A1 GO:0071230| cellular response to amino acid stimulus GLRA1;GLRA2 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2C;GLRA1;TRPV1;GLRB;GRIN3B;OPRM1;GLRA3;SLC29A1;CHRNA7;GRIN2A;GLRA2 GO:0022900| electron transport chain IDO1;GSR;GLDC;CYP1A2 GO:0006631| fatty acid metabolic process PTGS1;BAAT;PTGS2;ALOX15 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0050905| neuromuscular process GLRB;GLRA1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;GRIN2A;CYP1A2;PTGS2;SOD1;HTR2A GO:0050884| neuromuscular process controlling posture GLRA1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;GLDC;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;PIPOX;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;GPX1;PTGS1 GO:0006821| chloride transport GLRA1;GLRB;GLRA3;GLRA2 GO:1900273| GRIN2A;CHRNA7 GO:0070588| calcium ion transmembrane transport CACNA1G;TRPA1;TRPV4;GRIN3B;CACNA1I;TRPV1;TRPM8;OPRM1;CACNA1H;TRPV3;TRPV2;CHRNA7 GO:0065009| regulation of molecular function GRIN2A;GRIN2C;TRPV1 GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0060012| synaptic transmission, glycinergic GLRB;GLRA1;SLC6A5;GLRA2;GLRA3 GO:0001975| response to amphetamine GRIN2A;CNR2;SOD1 GO:0019216| regulation of lipid metabolic process ALAS1;CNR1;HMGCR;PPARG;CYP1A1 GO:0051384| response to glucocorticoid stimulus AGXT;PTGS2 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB GO:0022008| neurogenesis DAGLA;GRIN2A GO:0002305| CD8-positive, gamma-delta intraepithelial T cell differentiation GPR18 GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0007613| memory GRIN2A;CHRNA7;PTGS2;CNR1;HTR2A GO:0051291| protein heterooligomerization GLRB;GLRA1 GO:0009636| response to toxin GPX1;CAT;GLYAT;CYP1B1;CYP1A1 GO:0002689| negative regulation of leukocyte chemotaxis GPR18 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;GRIN2A GO:0006811| ion transport GLRA2;CHRNA7;GRIN2A;TRPV2;SLC36A1;GLRA3;CACNA1H;TRPV3;SLC32A1;TRPM8;TRPV1;GRIN3B;CACNA1I;TRPV4;GLRB;VDAC1;TRPA1;GLRA1;GRIN2C;CACNA1G GO:0042428| serotonin metabolic process GRIN2A;HTR1A GO:0006778| porphyrin-containing compound metabolic process CYP1A2;ALAS1;CYP1A1;ALAS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;GLYAT;PTGS1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0008152| metabolic process ACAT1;ALAS1;SMPD1;GCAT;ALAS2 GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0097305| GLRA1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;BAAT;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0071361| cellular response to ethanol GLRA2;GLRA1 GO:0060078| regulation of postsynaptic membrane potential GRIN2A;CHRNA7 GO:0007399| nervous system development GSS;GLRB;SMPD1 GO:0071294| cellular response to zinc ion GLRA2;GLRA1 GO:0019233| sensory perception of pain GRIN2A;HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2;TRPV1;TRPA1 GO:0001889| liver development ACAT1;BAAT;CYP1A1 GO:0030431| sleep SLC29A1;GRIN2A;HTR2A;CACNA1I GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;GRIN2A;CAT GO:0060013| righting reflex GLRA1;GLRB GO:0001964| startle response GRIN2A;GLRB;GLRA1 GO:0006816| calcium ion transport TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;GRIN2A;CHRNA7;TRPV2;TRPV3;CACNA1H GO:0030217| T cell differentiation GPR18 GO:0051289| protein homotetramerization GNMT;SHMT1;CAT;CRYZ;TRPA1;SHMT2;TRPV1;TRPM8 GO:0002300| CD8-positive, alpha-beta intraepithelial T cell differentiation GPR18 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2;ALAS2 GO:0008542| visual learning HMGCR;GRIN2A GO:0051924| regulation of calcium ion transport OPRD1;GRIN3B GO:1902476| GLRB;GLRA1;GLRA2;GLRA3 GO:0031667| response to nutrient levels GSS;SOD1 GO:0007268| synaptic transmission GLRA1;CACNA1G;VDAC1;GLRB;GLRA3;HTR2A;OPRD1;OPRM1;GRIN2A;SLC6A5;GLRA2 17986:[DB14011 DB04410] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways GO:0043312| neutrophil degranulation PRSS2;CAT;ALOX5 GO:0009235| cobalamin metabolic process ABCC1;PRSS1 17987:[DB14011 DB14017] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14017|H3B-8800 SF3B1 common genes common pathways 17988:[DB14011 DB06346] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06346|Fiboflapon ALOX5AP common genes common pathways GO:0019370| leukotriene biosynthetic process ALOX5AP;ALOX5;PLA2G1B GO:0071277| cellular response to calcium ion ALOX15;ALOX5AP GO:0019372| lipoxygenase pathway ALOX5AP;ALOX5;GPX1;PTGS2;ALOX15 GO:0006691| leukotriene metabolic process ALOX5;ALOX5AP;ALOX15;ABCC1 GO:0070207| protein homotrimerization TRPM8;ALOX5AP GO:2001300| ALOX5;ALOX5AP GO:0043085| positive regulation of catalytic activity SOD1;ALOX5AP 17989:[DB14011 DB00888] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00888|Mechlorethamine BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BCHE;PTGS2;OPRM1 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;BCHE;ABCG2 17990:[DB14011 DB03918] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03918|6S-5,6,7,8-Tetrahydrobiopterin NOS3 common genes common pathways GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development NOS3;CYP1A2 GO:0042311| vasodilation GPX1;NOS3 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;NOS3;CYP2D6;CYP1A1;CYP2C9;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 GO:0001525| angiogenesis CYP1B1;NOS3;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat TRPV2;SOD1;TRPV3;NOS3;TRPV1 GO:0045454| cell redox homeostasis NOS3;GSR;GPX1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CYP1B1;PPARG;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;NOS3;PPARG GO:1902042| GPX1;NOS3 17991:[DB14011 DB00052] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00052|Somatotropin GHR;PRLR common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;GHR GO:0032355| response to estradiol stimulus GHR;PTGS2;CYP1A2;CAT GO:0006631| fatty acid metabolic process PTGS1;PTGS2;GHR;ALOX15 GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;PRLR GO:0043066| negative regulation of apoptotic process HMGCR;PRLR;PTGS2;SOD1;GPX1;CAT GO:0007566| embryo implantation SOD1;PRLR;PTGS2 GO:0040014| regulation of multicellular organism growth SOD1;GHR GO:0032870| cellular response to hormone stimulus CACNA1H;GHR GO:0007595| lactation SLC29A1;PRLR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation GHR;HTR2A GO:0007166| cell surface receptor linked signaling pathway PRLR;TRPA1;TRPV1 17992:[DB14011 DB05967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05967|ANZ-100 KISS1R common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;KISS1R;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger KISS1R;OPRD1;OPRM1;HTR2A GO:0007218| neuropeptide signaling pathway GLRB;GLRA1;KISS1R;GLRA3;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway KISS1R;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;GPR18;PPARG 17993:[DB14011 DB12243] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways GO:0098656| SLC22A8;VDAC1;SLC22A6 GO:0006811| ion transport TRPM8;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;SLC22A8;CACNA1H;TRPV3 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;SLC22A6;CACNA1G;ABCC1;TRPV2;SLC22A8;CACNA1H;TRPV3 17994:[DB14011 DB05448] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05448|PX-12 TXNRD1 common genes common pathways GO:0098869| GSR;PTGS2;PTGS1;GPX1;TXNRD1;CAT GO:0034599| cellular response to oxidative stress SOD1;CAT;TXNRD1;GPX1;GSR GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;TXNRD1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP2C9;CYP1A1;CRYZ GO:0022900| electron transport chain CYP1A2;TXNRD1;GSR;IDO1 GO:0045454| cell redox homeostasis GPX1;TXNRD1;GSR GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;TXNRD1;PPARG;CYP1A1 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;TXNRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0015949| nucleobase-containing small molecule interconversion TXNRD1;GSR GO:0008283| cell proliferation HTR1A;GPX1;TXNRD1;CYP1A1 17995:[DB14011 DB11421] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11421|Imidacloprid CHRFAM7A common genes common pathways GO:0034220| ion transmembrane transport CHRNA7;GLRA3;CHRFAM7A;GLRB;TRPV1;TRPA1;GLRA1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;CHRFAM7A;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;CHRFAM7A;GLRA3;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;CACNA1G;TRPA1;GLRA1 17996:[DB14011 DB07151] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07151|4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one PIM1 common genes common pathways GO:0008283| cell proliferation PIM1;HTR1A;GPX1;CYP1A1 GO:0006915| apoptotic process GPX1;PIM1;VDAC1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PIM1;PTGS2 17997:[DB14011 DB04282] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04282|2-deoxy-2-fluoro-α-D-glucose LCT common genes common pathways GO:0008152| metabolic process ACAT1;LCT;SMPD1 17998:[DB14011 DB11830] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC2;HDAC3;TRPV1;TRPV4;PPARG;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;HDAC1;PLA2G1B;HDAC2;HDAC3 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;HDAC2;HDAC1 GO:0043066| negative regulation of apoptotic process HDAC1;HDAC2;CAT;HDAC3;GPX1;SOD1;PTGS2;HMGCR GO:0071300| cellular response to retinoic acid PPARG;HDAC2 GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;HDAC1;GSR GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;HDAC2;CYP1A1;HDAC1;IDO1 GO:0007623| circadian rhythm AANAT;HDAC3 GO:0035094| response to nicotine CHRNA7;HDAC2;CNR1 GO:0055093| response to hyperoxia HDAC2;CAT;HDAC1;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent HDAC3;HDAC2;HDAC1;PPARG GO:0042493| response to drug ABCG2;CYP1A1;PPARG;HDAC1;TRPA1;SMPD1;ABCC1;HDAC2;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;PPARG;HDAC1 GO:0034605| cellular response to heat PTGS2;HDAC2;TRPV1;TRPV4 GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;HDAC1;PPARG GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC1 GO:0048511| rhythmic process HDAC1;PPARG;AANAT;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent HDAC3;HDAC2;HDAC1;PPARG GO:0031000| response to caffeine HDAC2;PPARG;HDAC1 GO:0010977| negative regulation of neuron projection development HDAC2;TRPV4 GO:0042220| response to cocaine SMPD1;OPRM1;CNR1;HDAC2 GO:0006351| transcription, DNA-dependent HDAC2;HDAC3;PPARG;HDAC1 GO:0071498| cellular response to fluid shear stress PTGS2;HDAC3 GO:0016032| viral reproduction VDAC1;HDAC1;HTR2A GO:0001934| positive regulation of protein phosphorylation HDAC3;CHRNA7 GO:0043524| negative regulation of neuron apoptosis SOD1;HDAC1 GO:0010629| negative regulation of gene expression OPRD1;HDAC1 GO:0048149| behavioral response to ethanol OPRM1;HDAC2 GO:0001975| response to amphetamine CNR2;SOD1;HDAC2;HDAC1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HDAC3;HMGCR;CNR1 GO:0070301| cellular response to hydrogen peroxide HDAC2;CYP1B1 GO:0008285| negative regulation of cell proliferation PPARG;HDAC1;CYP1B1;PTGS2;OPRM1 17999:[DB14011 DB02080] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02080|1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene PLA2G2A;lepB;TTPA common genes common pathways GO:0009636| response to toxin CYP1B1;CYP1A1;TTPA;GPX1;CAT GO:0036150| PLA2G1B;PLA2G2A GO:0007584| response to nutrient CNR1;HMGCR;TTPA;PPARG GO:0001890| placenta development SOD1;PPARG;TTPA GO:0032502| developmental process TTPA;CYP1A1 GO:0050729| positive regulation of inflammatory response TRPV4;PLA2G2A GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2A GO:0009268| response to pH TTPA;TRPV1 GO:0036149| PLA2G2A;PLA2G1B GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1;CYP2C9;PPARG;TTPA;DAGLA;CYP2D6;PLA2G2A;ALOX15;TRPV1;PLA2G1B GO:0036148| PLA2G2A;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;PLA2G2A;TRPV4 GO:0016042| lipid catabolic process PLA2G1B;DAGLA;PLA2G2A;NAPEPLD GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;PLA2G2A GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1;TTPA GO:0006810| transport TRPV2;ABCC1;TTPA;CACNA1I;TRPV1;ABCG2 GO:0036152| PLA2G2A;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;PLA2G2A GO:0036151| PLA2G1B;PLA2G2A GO:0006654| phosphatidic acid biosynthetic process PLA2G2A;PLA2G1B 18000:[DB14011 DB03298] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03298|Phenylphosphate SRC common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;GPX1;SRC GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;SRC;PTGS2;CNR1;SOD1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;SRC GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;SRC;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0045453| bone resorption GPR55;SRC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;SRC;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;SRC;GPX1 GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0009615| response to virus CYP1A1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0002376| immune system process IDO1;SRC 18001:[DB14011 DB05532] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05532|BMS-488043 FFAR4 common genes common pathways GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;FFAR4;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0032870| cellular response to hormone stimulus FFAR4;CACNA1H GO:0045444| fat cell differentiation FFAR4;GPX1 GO:0050728| negative regulation of inflammatory response FFAR4;CNR2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;FFAR4;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;FFAR4;HMGCR;OPRM1;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;FFAR4;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A 18002:[DB14011 DB05449] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05449|FM-VP4 ABCB1 common genes common pathways GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0042493| response to drug ABCB1;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport TRPV1;ABCB1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H 18003:[DB14011 DB07180] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways 18004:[DB14011 DB09348] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09348|Propiolactone ALB common genes common pathways GO:0001895| retina homeostasis ALB;SOD1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0098869| ALB;GSR;CAT;GPX1;PTGS1;PTGS2 18005:[DB14011 DB14001] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14001|alpha-Tocopherol succinate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes ALOX5;SOD1 common pathways GO:0048538| thymus development SOD1 GO:0051260| protein homooligomerization GLRA3;HMOX1;ACAT1;GLRA1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;GSTP1;CHRNA7 GO:0002376| immune system process IDO1;PRKCB GO:0031100| organ regeneration GSTP1;PPARG GO:0006979| response to oxidative stress HMOX1;SOD1;PTGS2;CAT;GCLC;GPX1;PTGS1;NQO1 GO:0098869| GSTO1;PTGS2;CAT;PTGS1;GPX1;GSR;GSTP1 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;PRKCB;TRPM8;TRPV4 GO:0043085| positive regulation of catalytic activity SOD1 GO:0007605| sensory perception of sound GPX1;SOD1 GO:0042554| superoxide anion generation SOD1 GO:0032355| response to estradiol stimulus NQO1;GSTP1;CYP1A2;PTGS2;CAT GO:0034605| cellular response to heat TRPV1;TRPV4;HMOX1;PTGS2 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1A1;CYP2C9;NR1I2;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;HMOX1;SLC29A1 GO:0010468| regulation of gene expression CYP1A2;PPP2CB GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TTPA;TRPV2 GO:0007568| aging NQO1;CYP1A1;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT;GCLC GO:0007283| spermatogenesis SOD1;CNR1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0001666| response to hypoxia CYP1A1;HMOX1;CHRNA7;CAT;PRKCB GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0046688| response to copper ion SOD1;AANAT GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1;TTPA GO:0046716| muscle cell homeostasis SOD1 GO:0043407| negative regulation of MAP kinase activity SMPD1;GSTP1;HMGCR GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;GCLC GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPP2CA;CYP1A1;PPARG;TRPA1 GO:2001300| ALOX5 GO:0046686| response to cadmium ion GCLC;CAT GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0043200| response to amino acid stimulus GLRA3;GLRB;GSTP1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;PRKCA;ALOX15 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;SEC14L2 GO:0008219| cell death HTR2A;HMOX1 GO:0001541| ovarian follicle development SOD1 GO:0045766| positive regulation of angiogenesis PRKCA;CYP1B1;HMOX1;CHRNA7;PRKCB GO:0006915| apoptotic process PRKCB;GPX1;HMOX1;PRKCA;PPP2CA;VDAC1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B GO:0030855| epithelial cell differentiation VDAC1;PPARG;GSTA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1I2;PLA2G1B GO:0007626| locomotory behavior OPRM1;SOD1 GO:0046677| response to antibiotic CYP1A1;PPP2CB;SOD1 GO:0002576| platelet degranulation SOD1 GO:0043066| negative regulation of apoptotic process GPX1;GCLC;CAT;HMGCR;PTGS2;SOD1;GSTP1;NQO1 GO:0006654| phosphatidic acid biosynthetic process DGKA;PLA2G1B GO:0035722| interleukin-12-mediated signaling pathway SOD1;GSTA2;GSTO1 GO:1902177| SOD1 GO:0032259| methylation CYP1A2;GSTO1 GO:0007155| cell adhesion PRKCA;CYP1B1 GO:0043312| neutrophil degranulation GSTP1;ALOX5;CAT GO:0000302| response to reactive oxygen species SOD1;GPX1;CAT;GSTP1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0009410| response to xenobiotic stimulus GCLC;GPX1 GO:0030308| negative regulation of cell growth PPP2CA;PPARG GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;GSR;GSTP1 GO:0097332| SOD1 GO:0071333| cellular response to glucose stimulus GCLC;SLC29A1 GO:0034465| response to carbon monoxide SOD1 GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;HMOX1 GO:0019372| lipoxygenase pathway GPX1;ALOX5;PTGS2;ALOX15 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2 GO:0035094| response to nicotine CNR1;HMOX1;CHRNA7 GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;PPARG;PPP2CA;PRKCB;SEC14L2 GO:0046685| response to arsenic-containing substance CYP1A1;GCLC GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent SEC14L2;PPARG;NR1I2 GO:0007569| cell aging SOD1 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMOX1;GSTO1;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP2C9;CYP1A1;NQO1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1 GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0060047| heart contraction SOD1;GPX1 GO:0048662| negative regulation of smooth muscle cell proliferation HMOX1;PPARG GO:0001819| positive regulation of cytokine production SOD1 GO:0009725| response to hormone stimulus ACAT1;GCLC GO:0007165| signal transduction GPR18;NR1I2;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;PRKCB GO:0072593| reactive oxygen species metabolic process SOD1 GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0045454| cell redox homeostasis GSR;GCLC;GPX1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0040014| regulation of multicellular organism growth SOD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0050796| regulation of insulin secretion PRKCA;CNR1 GO:0032869| cellular response to insulin stimulus PLA2G1B;GSTP1;PPARG;GCLC GO:0042908| xenobiotic transport NR1I2;ABCC1;ABCG2 GO:0032502| developmental process TTPA;CYP1A1 GO:0002262| myeloid cell homeostasis SOD1 GO:0006749| glutathione metabolic process GSTO1;SOD1;GSTA2;GPX1;GCLC;GSTM3;GSTP1;GSR GO:0034976| response to endoplasmic reticulum stress PPP2CB;ALOX15 GO:0071276| cellular response to cadmium ion HMOX1;SOD1;CYP1A2 GO:0042178| xenobiotic catabolic process GSTO1;GSTM3;CRYZ GO:0001890| placenta development SOD1;PPARG;TTPA GO:1902042| GPX1;HMOX1 GO:0007584| response to nutrient NQO1;TTPA;PPARG;GCLC;HMGCR;CNR1 GO:0032930| positive regulation of superoxide anion generation SOD1;GSTP1 GO:0070301| cellular response to hydrogen peroxide NQO1;CYP1B1 GO:0043627| response to estrogen stimulus HMOX1;GSTM3;PPARG GO:0014823| response to activity GCLC;CAT GO:0008217| regulation of blood pressure PPARG;SOD1;HMOX1;PTGS2;PTGS1 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0008285| negative regulation of cell proliferation HMOX1;PTGS2;OPRM1;CYP1B1;PPARG GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0009636| response to toxin GSTP1;CYP1B1;CYP1A1;TTPA;NQO1;CAT;GPX1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;NQO1;CYP1A1;PPARG GO:0046620| regulation of organ growth SOD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0001895| retina homeostasis SOD1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NQO1 GO:0042542| response to hydrogen peroxide GPX1;CAT;HMOX1;SOD1;TRPA1;PPP2CB GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0043065| positive regulation of apoptotic process HMOX1;SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0008152| metabolic process GSTP1;GSTM3;SMPD1;ACAT1;GSTO1;GSTA2;DGKA GO:0035556| intracellular signal transduction PLA2G1B;PRKCA;DGKA;HMOX1;PRKCB GO:0006805| xenobiotic metabolic process NQO1;CYP2C9;NR1I2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;GSTP1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0042953| lipoprotein transport PPARG;PRKCB GO:0071260| cellular response to mechanical stimulus PTGS2;GCLC GO:0006629| lipid metabolic process CYP2C9;PPARG;TTPA;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;PTGS1;GPX1 GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;PPARG GO:0000303| response to superoxide SOD1 GO:0008090| retrograde axon cargo transport SOD1 GO:0001525| angiogenesis PRKCA;CYP1B1;HMOX1;PTGS2 GO:0045471| response to ethanol SOD1;CNR1;OPRM1;HMGCR;CAT;NQO1;GSTP1 GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0006351| transcription, DNA-dependent NR1I2;PPARG;PRKCB;SEC14L2 GO:0048678| response to axon injury SOD1 GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;ALOX5;PTGS1;CNR2;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PRKCB;PLA2G1B GO:0009408| response to heat TRPV2;GCLC;TRPV3;SOD1;TRPV1 GO:0043087| regulation of GTPase activity SOD1 GO:0019226| transmission of nerve impulse SOD1 GO:0006816| calcium ion transport TRPV2;PRKCB;CHRNA7;TRPV3;CACNA1H;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1 GO:0019430| removal of superoxide radicals SOD1;NQO1 GO:1904706| GSTP1;PPARG;HMOX1 GO:0006879| cellular iron ion homeostasis SOD1;HMOX1;ABCG2 GO:0009268| response to pH TTPA;TRPV1 GO:0043524| negative regulation of neuron apoptosis GCLC;SOD1;HMOX1 GO:0042738| exogenous drug catabolic process CYP2C19;NR1I2;CYP2C9;CYP3A4;CYP1A2 GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels GSTP1;SOD1 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0060052| neurofilament cytoskeleton organization SOD1 18006:[DB14011 DB04988] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04988|IGN311 EGFR;ERBB2 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0007507| heart development ERBB2;PPARG GO:0001503| ossification EGFR;ALOX15 GO:0007399| nervous system development GLRB;SMPD1;ERBB2 GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0051592| response to calcium ion EGFR;AANAT GO:0006351| transcription, DNA-dependent ERBB2;PPARG GO:0001889| liver development ACAT1;EGFR;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway ERBB2;TRPA1;EGFR;TRPV1 GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;PPARG;ERBB2 GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7;ERBB2 GO:0007165| signal transduction HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;ERBB2;GPR18;PPARG;SMPD1;EGFR;CACNA1I;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;EGFR GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;ERBB2 GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0032930| positive regulation of superoxide anion generation SOD1;EGFR GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;EGFR GO:0071276| cellular response to cadmium ion EGFR;SOD1;CYP1A2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;EGFR;CYP1A1;PPARG;TRPA1 GO:0008283| cell proliferation CYP1A1;EGFR;HTR1A;ERBB2;GPX1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0008284| positive regulation of cell proliferation EGFR;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0030324| lung development EGFR;CYP1A2 GO:0071230| cellular response to amino acid stimulus GLRA1;EGFR GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;EGFR GO:0042060| wound healing ALOX15;EGFR;ERBB2;OPRM1 GO:0007623| circadian rhythm AANAT;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;ERBB2;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2;HMGCR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;EGFR GO:0006355| regulation of transcription, DNA-dependent PPARG;ERBB2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;EGFR;TRPV1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;EGFR GO:0033993| response to lipid PPARG;EGFR GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;EGFR GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;OPRD1;CAT;ERBB2 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A;ERBB2 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EGFR GO:0010628| positive regulation of gene expression ERBB2;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;EGFR;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 18007:[DB14011 DB08058] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 18008:[DB14011 DB01760] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01760|2-Methoxy-3-Isopropylpyrazine LCN9 common genes common pathways 18009:[DB14011 DB07739] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07739|(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 18010:[DB14011 DB09539] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways GO:0006629| lipid metabolic process HMGCR;PTGS2;SOAT1;CYP1A2;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0008203| cholesterol metabolic process SOAT1;HMGCR;CAT GO:0033344| cholesterol efflux SOAT1;ABCG2 GO:0010742| macrophage derived foam cell differentiation PPARG;SOAT1 GO:0008202| steroid metabolic process HMGCR;CYP1A2;SOAT1;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1 18011:[DB14011 DB03953] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03953|L-Thiocitrulline NOS2 common genes common pathways GO:0045454| cell redox homeostasis NOS2;GSR;GPX1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0001666| response to hypoxia NOS2;CYP1A1;CHRNA7;CAT GO:0032496| response to lipopolysaccharide NOS2;CYP1A1;IDO1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NOS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;NOS2;CRYZ;CYP2C9;CYP1A1 18012:[DB14011 DB06733] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;TRPV2;ATP6V1A GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;TRPV1;GLRA3;ATP6V1A;CHRNA7 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;ATP6V1A GO:0006811| ion transport ATP6V1A;CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;GLRA1;TRPA1;CACNA1G 18013:[DB14011 DB02933] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways GO:0035722| interleukin-12-mediated signaling pathway MTAP;SOD1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;MTAP 18014:[DB14011 DB02056] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;AKR1C3;PTGS2;CHRNA7 GO:0007218| neuropeptide signaling pathway GLRA3;OPRM1;OPRD1;PTGDR2;GLRA1;GLRB GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;AKR1C3 GO:0055114| oxidation-reduction process CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1;PTGS1;ALOX5;GPX1;CAT;HMGCR;AKR1C3;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0042574| retinal metabolic process CYP1B1;AKR1C3 GO:0008202| steroid metabolic process CYP3A4;AKR1C3;HMGCR;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;AKR1C3;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PTGDR2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1;PTGDR2 GO:0055085| transmembrane transport TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;SLCO2A1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2;AKR1C3 GO:0042572| retinol metabolic process AKR1C3;CYP1B1 GO:0000060| protein import into nucleus, translocation OPRD1;AKR1C3 GO:0071277| cellular response to calcium ion AKR1C3;ALOX15 GO:0042448| progesterone metabolic process AKR1C3;CYP17A1 GO:0006955| immune response CNR2;OPRD1;PTGDR2 GO:0010942| positive regulation of cell death PTGS2;AKR1C3 GO:0071379| cellular response to prostaglandin stimulus AKR1C3;PPARG GO:0019371| cyclooxygenase pathway PTGS2;AKR1C3;PTGS1 GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;OPRM1;OPRD1;GLRA3;HTR2A;PTGDR2 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;PTGDR2;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;PTGDR2 GO:0001523| retinoid metabolic process NAPEPLD;AKR1C3 GO:0071276| cellular response to cadmium ion SOD1;AKR1C3;CYP1A2 GO:0007584| response to nutrient HMGCR;AKR1C3;CNR1;PPARG 18015:[DB14011 DB01294] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR;ALB GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB GO:0002576| platelet degranulation ALB;SOD1;TF GO:0001895| retina homeostasis SOD1;TF;ALB GO:0006811| ion transport GLRA3;CACNA1H;TRPV3;TF;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1 GO:0006879| cellular iron ion homeostasis SOD1;TF;ABCG2 18016:[DB14011 DB06643] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06643|Denosumab TNFSF11 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0051260| protein homooligomerization GLRA3;TNFSF11;ACAT1;GLRA1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;TNFSF11 GO:0046330| positive regulation of JNK cascade TRPV4;TNFSF11 GO:0045453| bone resorption GPR55;TNFSF11 GO:0006955| immune response OPRD1;TNFSF11;CNR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;TNFSF11 GO:0001503| ossification ALOX15;TNFSF11 18017:[DB14011 DB04723] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways 18018:[DB14011 DB00105] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00105|Interferon Alfa-2b, Recombinant IFNAR2;IFNAR1;CYP1A2 common genes CYP1A2 common pathways GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALOX5;GPX1;PTGS1 GO:0009615| response to virus IFNAR2;IFNAR1;CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;IFNAR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0010468| regulation of gene expression CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNAR2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 18019:[DB14011 DB04653] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04653|CBZ-LEU-LEU-TYR-CH2F CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;CAPN1;HMGCR;CHRNA7 GO:0043312| neutrophil degranulation ALOX5;CAT;CAPN1 18020:[DB14011 DB02565] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways GO:0010629| negative regulation of gene expression HDAC8;OPRD1 GO:0006351| transcription, DNA-dependent HDAC8;PPARG GO:0006355| regulation of transcription, DNA-dependent HDAC8;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;HDAC8 18021:[DB14011 DB07048] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07048|N-[(2R)-5-(aminosulfonyl)-2,3-dihydro-1H-inden-2-yl]-2-propylpentanamide CA2 common genes common pathways GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0001822| kidney development CA2;CAT 18022:[DB14011 DB01022] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 18023:[DB14011 DB03166] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;SLCO2B1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;SLC16A1;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2 GO:0042593| glucose homeostasis TRPV4;PPARG;SLC16A1;CNR1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;SLC16A1;ABCC1;CACNA1G;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;SLCO2B1;TRPM8;ABCG2 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1A1;CYP1B1 GO:0032094| response to food CYP1A1;OPRM1;SLC16A1 18024:[DB14011 DB07616] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;HPGDS;CHRNA7 GO:0006633| fatty acid biosynthetic process PTGS1;HPGDS;PTGS2;PLA2G1B GO:0001516| prostaglandin biosynthetic process PTGS1;HPGDS;PTGS2 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;HPGDS;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1;HPGDS GO:0019371| cyclooxygenase pathway PTGS2;HPGDS;PTGS1 GO:0007626| locomotory behavior HPGDS;SOD1;OPRM1 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1;HPGDS 18025:[DB14011 DB07136] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 18026:[DB14011 DB04576] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes CYP1A2 common pathways GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0048511| rhythmic process PPARG;TOP2A;AANAT GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0010468| regulation of gene expression CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TOP2A GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;TOP2A;PPARG;PTGS2;CNR1;SOD1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9 18027:[DB14011 DB02337] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways GO:0032259| methylation BHMT;CYP1A2 18028:[DB14011 DB14641] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;ESR1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;ESR2;SMPD1;PPARG;GPR18 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;ESR1;HTR2A;OPRM1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLCO1A2;TRPV3;CACNA1H;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPA1;GLRA1;CACNA1G GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;ESR2;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0006810| transport TRPV2;ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2 GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV4;ABCB1;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;SLCO1A2;TRPV2 18029:[DB14011 DB00116] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCC1 GO:0006139| nucleobase-containing compound metabolic process ATIC;SLC29A1 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0007565| female pregnancy IDO1;ABCC2 GO:0051289| protein homotetramerization CAT;SHMT1;TRPV1;TRPM8;SHMT2;TRPA1;CRYZ GO:0009408| response to heat ABCC2;TRPV1;SOD1;TRPV3;TRPV2 GO:0048678| response to axon injury MTR;SOD1 GO:0007507| heart development PPARG;MTHFD1 GO:0007399| nervous system development MTR;SMPD1;GLRB GO:0008152| metabolic process MTHFR;ACAT1;ALDH1L1;ATIC;SMPD1;MTHFD1;MTHFD2;FTCD GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;ABCC2;TRPM8;ABCG2 GO:0043200| response to amino acid stimulus MTHFR;GLRA3;GLRB GO:0051262| protein tetramerization SHMT2;CAT;SHMT1;HMGCR GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;MTHFR GO:0006810| transport ABCG2;ABCC2;TRPV1;CACNA1I;ABCC1;TRPV2 GO:0009235| cobalamin metabolic process MTR;ABCC1 GO:0006979| response to oxidative stress ABCC2;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0031100| organ regeneration ATIC;PPARG GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;ALDH1L1;CYP1A1;CYP2C9;MTHFD1;MTHFD2;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;MTHFR;CYP1A2;PTGS2;CYP3A7 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC2;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;HTR2A;SOD1;MTHFR;CYP1A2;PTGS2 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;ABCC2;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0032259| methylation AMT;MTR;CYP1A2 GO:0008284| positive regulation of cell proliferation SHMT2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 18030:[DB14011 DB02063] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02063|CRA_16847 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18031:[DB14011 DB02158] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways GO:0035722| interleukin-12-mediated signaling pathway SOD1;MTAP GO:0006139| nucleobase-containing compound metabolic process MTAP;SLC29A1 18032:[DB14011 DB05033] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05033|INCB7839 ADAM9 common genes common pathways GO:0050714| positive regulation of protein secretion PLA2G1B;ADAM9 GO:0034612| response to tumor necrosis factor ADAM9;PTGS2 GO:0010042| response to manganese ion ADAM9;PTGS2 GO:0007155| cell adhesion CYP1B1;ADAM9 GO:0051384| response to glucocorticoid stimulus ADAM9;PTGS2 GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;ADAM9;TRPA1 GO:0051592| response to calcium ion ADAM9;AANAT 18033:[DB14011 DB13998] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;CALR GO:0010977| negative regulation of neuron projection development TRPV4;LRP1 GO:0043277| apoptotic cell clearance ALOX15;LRP1 GO:0007283| spermatogenesis CALR;CNR1;SOD1 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;CALR;TRPA1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CALR GO:0042220| response to cocaine CNR1;OPRM1;HSPA5;SMPD1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CALR;CHRNA7;HTR2A;GPR12 GO:0051260| protein homooligomerization ACAT1;GLRA3;VWF;GLRA1 GO:0032355| response to estradiol stimulus CALR;CAT;PTGS2;CYP1A2 GO:0009611| response to wounding GPX1;VWF;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0007568| aging CYP1A1;LRP1;CANX;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0030282| bone mineralization ASGR2;PTGS2;ALOX15 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0050728| negative regulation of inflammatory response CNR2;PROC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 GO:0006631| fatty acid metabolic process PHYH;ALOX15;PTGS2;PTGS1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;PPARG;CYP1A1;CALR;TRPA1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0055114| oxidation-reduction process CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;PHYH;CYP1A1;CYP2C9;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CANX GO:0043066| negative regulation of apoptotic process HSPA5;PTGS2;HMGCR;SOD1;GPX1;PROC;CAT GO:0002576| platelet degranulation SOD1;VWF GO:0008284| positive regulation of cell proliferation F2;CALR;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007155| cell adhesion VWF;CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;CALR GO:0055088| lipid homeostasis ASGR2;PPARG GO:0045740| positive regulation of DNA replication PLA2G1B;CALR GO:0001523| retinoid metabolic process NAPEPLD;LRP1 GO:0034976| response to endoplasmic reticulum stress HSPA5;ALOX15 GO:0061844| PLA2G1B;F2 GO:0008283| cell proliferation GPX1;HTR1A;LRP1;CYP1A1 GO:0010976| positive regulation of neuron projection development CNR1;HSPA5 GO:0010942| positive regulation of cell death PTGS2;LRP1 GO:0071320| cellular response to cAMP AANAT;HSPA5 GO:0043524| negative regulation of neuron apoptosis LRP1;SOD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0009314| response to radiation HSPA5;CAT;PTGS2;OPRM1 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;LRP1;GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0042953| lipoprotein transport PPARG;LRP1 GO:1990090| HSPA5;TRPV1 GO:0001889| liver development ACAT1;PROC;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1;ASGR2 GO:0071277| cellular response to calcium ion HSPA5;ALOX15 18034:[DB14011 DB08835] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;SLC36A1;CHRNA7 GO:0008152| metabolic process ACAT1;FOLH1;SMPD1 GO:0055085| transmembrane transport TRPV2;SLC36A1;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 18035:[DB14011 DB05460] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05460|Ezatiostat GSTP1 common genes common pathways GO:0000302| response to reactive oxygen species GSTP1;CAT;GPX1;SOD1 GO:0034599| cellular response to oxidative stress GPX1;CAT;SOD1;GSTP1;GSR GO:0043066| negative regulation of apoptotic process GSTP1;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0043312| neutrophil degranulation CAT;ALOX5;GSTP1 GO:0043200| response to amino acid stimulus GLRA3;GLRB;GSTP1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0032355| response to estradiol stimulus GSTP1;CAT;PTGS2;CYP1A2 GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production GPR18;GSTP1;CHRNA7 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR;GSTP1 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:1904706| PPARG;GSTP1 GO:0045471| response to ethanol GSTP1;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0008152| metabolic process SMPD1;GSTP1;ACAT1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;GSTP1;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1;GSTP1 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0006749| glutathione metabolic process SOD1;GPX1;GSTP1;GSR GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;GSTP1 18036:[DB14011 DB03288] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;PYGL GO:0042593| glucose homeostasis CNR1;PYGL;PPARG;TRPV4 GO:0043312| neutrophil degranulation PYGL;CAT;ALOX5 18037:[DB14011 DB05299] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways GO:0002376| immune system process IL2;IDO1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;IL2;PPARG;GPR18 GO:0050728| negative regulation of inflammatory response CNR2;IL2 GO:0043066| negative regulation of apoptotic process IL2;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IL2;PLA2G1B GO:0007155| cell adhesion CYP1B1;IL2 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0050729| positive regulation of inflammatory response IL2;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration IL2;TRPV4;TRPV1;HTR2A;OPRM1 GO:0006955| immune response CNR2;OPRD1;IL2 GO:0030217| T cell differentiation IL2;GPR18 GO:0001934| positive regulation of protein phosphorylation CHRNA7;IL2 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;IL2 18038:[DB14011 DB04877] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04877|Voacamine ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1;CACNA1H;TRPV3;TRPV2 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCB1;ABCG2;TRPV2 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;ABCB1 18039:[DB14011 DB03114] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03114|PAS219 SRC common genes common pathways GO:0008283| cell proliferation HTR1A;SRC;GPX1;CYP1A1 GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;SRC;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0045453| bone resorption GPR55;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0031667| response to nutrient levels SOD1;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;SRC;TRPA1 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;SRC;PTGS2;CNR1;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;SRC;CHRNA7;TRPV4;ALOX15 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0002376| immune system process SRC;IDO1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug SRC;CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;SRC;GPX1 GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0009615| response to virus SRC;CYP1A1 18040:[DB14011 DB02105] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;COMT;CYP1A1;IDO1 GO:0007612| learning PTGS2;VDAC1;COMT GO:0007614| short-term memory COMT;CHRNA7 GO:0032259| methylation COMT;CYP1A2 GO:0042493| response to drug ABCG2;COMT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0048265| response to pain COMT;TRPA1;TRPV1 GO:0008210| estrogen metabolic process CYP1B1;COMT GO:0007565| female pregnancy COMT;IDO1 GO:0032502| developmental process CYP1A1;COMT GO:0048662| negative regulation of smooth muscle cell proliferation COMT;PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;COMT;AANAT;ACAT1;PTGS2;CYP1A2 GO:0051930| regulation of sensory perception of pain COMT;OPRD1;OPRM1 GO:0043627| response to estrogen stimulus PPARG;COMT 18041:[DB14011 DB04960] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04960|Tipifarnib FNTB common genes common pathways GO:0042127| regulation of cell proliferation FNTB;PTGS2;PTGS1 18042:[DB14011 DB03203] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0046718| entry of virus into host cell PVR;HTR2A GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0016032| viral reproduction HTR2A;PVR;VDAC1 GO:0006687| glycosphingolipid metabolic process SMPD1;GLTP GO:0006810| transport ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2;TRPV2 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV1;VDAC1;ABCB1;CACNA1I;TRPV4;TRPA1;ABCC1;CACNA1G GO:0007155| cell adhesion CYP1B1;PVR GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCB1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG 18043:[DB14011 DB00746] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00746|Deferoxamine APP;XDH common genes common pathways GO:0061844| APP;PLA2G1B GO:0032930| positive regulation of superoxide anion generation SOD1;APP GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;APP GO:0008344| adult locomotory behavior APP;OPRD1 GO:0006919| activation of caspase activity PPARG;XDH GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP GO:1900273| APP;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;APP;HTR2A;OPRM1 GO:0007613| memory APP;CHRNA7;PTGS2;HTR2A;CNR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRM1;OPRD1 GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0007595| lactation XDH;SLC29A1 GO:0008542| visual learning APP;HMGCR GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:1902004| APP;CHRNA7 GO:0001934| positive regulation of protein phosphorylation APP;CHRNA7 GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0071320| cellular response to cAMP AANAT;APP GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;GLRB;VDAC1;GLRA1;APP;CACNA1G GO:0010629| negative regulation of gene expression XDH;OPRD1;APP GO:0007399| nervous system development SMPD1;APP;GLRB GO:1990090| APP;TRPV1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;APP;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0001774| microglial cell activation APP;TRPV1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0051262| protein tetramerization CAT;HMGCR;APP GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;APP;ALOX15;TRPV4 GO:0000187| activation of MAPK activity SOD1;CHRNA7;APP;PLA2G1B GO:0006915| apoptotic process GPX1;APP;VDAC1 GO:0051260| protein homooligomerization GLRA1;APP;ACAT1;GLRA3 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress APP;CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0010468| regulation of gene expression CYP1A2;APP GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;APP;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0098815| CHRNA7;APP GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;XDH;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;PTGS1;GPX1 GO:0050808| synapse organization CHRNA7;APP GO:0019731| antibacterial humoral response PLA2G1B;APP GO:0050830| defense response to Gram-positive bacterium APP;PLA2G1B GO:0022900| electron transport chain XDH;CYP1A2;IDO1;GSR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;APP GO:0007155| cell adhesion APP;CYP1B1 GO:0045087| innate immune response PPARG;APP GO:0010288| response to lead ion APP;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;APP;PLA2G1B GO:0007626| locomotory behavior OPRM1;SOD1;APP GO:0002576| platelet degranulation APP;SOD1 GO:1905906| APP;CHRNA7 GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:0008203| cholesterol metabolic process HMGCR;CAT;APP GO:0007612| learning PTGS2;VDAC1;APP GO:0007611| learning or memory APP;CNR1;CHRNA7 18044:[DB14011 DB13988] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13988|SB-269970 HTR7 common genes common pathways GO:0007623| circadian rhythm HTR7;AANAT GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1;HTR7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0007268| synaptic transmission OPRM1;OPRD1;HTR2A;GLRA3;CACNA1G;GLRA1;VDAC1;GLRB;HTR7 GO:0042310| vasoconstriction HTR7;HTR1A GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR7;HTR1A GO:0007165| signal transduction HTR7;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0006939| smooth muscle contraction HTR7;HTR2A 18045:[DB14011 DB04350] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04350|Argadin CHIT1 common genes common pathways GO:0043312| neutrophil degranulation CHIT1;ALOX5;CAT GO:0006955| immune response CNR2;OPRD1;CHIT1 GO:0008152| metabolic process SMPD1;CHIT1;ACAT1 18046:[DB14011 DB07358] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07358|2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways GO:0042593| glucose homeostasis GCK;CNR1;PPARG;TRPV4 GO:0070509| calcium ion import CACNA1G;CACNA1I;TRPV4;CACNA1H;GCK GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;GCK GO:0050796| regulation of insulin secretion GCK;CNR1 GO:0008152| metabolic process SMPD1;GCK;ACAT1 18047:[DB14011 DB11726] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11726|Encenicline CHRNA7 common genes CHRNA7 common pathways GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902430| CHRNA7 GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;TRPV3 GO:0060078| regulation of postsynaptic membrane potential CHRNA7 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0050890| cognition CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1;CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1 GO:1904645| CHRNA7 GO:1900273| CHRNA7 GO:0050808| synapse organization CHRNA7 GO:0050893| sensory processing CHRNA7 GO:0035094| response to nicotine CHRNA7;CNR1 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0007614| short-term memory CHRNA7 GO:1905144| CHRNA7 GO:1905906| CHRNA7 GO:0007611| learning or memory CNR1;CHRNA7 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;ALOX15 GO:1905920| CHRNA7 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0095500| CHRNA7 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:1902991| CHRNA7 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0098815| CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;GPR12;HTR2A;CHRNA7 GO:1901214| CHRNA7 18048:[DB14011 DB00011] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00011|Interferon alfa-n1 IFNAR2;IFNAR1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway IFNAR2;TRPV1;TRPA1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;IFNAR1;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0009615| response to virus IFNAR1;IFNAR2;CYP1A1 18049:[DB14011 DB02908] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02908|RU78783 SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;SRC;SOD1;HTR2A;PTGS2;CYP1A2 GO:0016236| macroautophagy VDAC1;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0009612| response to mechanical stimulus TRPV4;PPARG;SRC GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;SRC;CAT GO:0009615| response to virus CYP1A1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0002376| immune system process SRC;IDO1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2;SRC GO:0042542| response to hydrogen peroxide TRPA1;SOD1;SRC;GPX1;CAT GO:0008283| cell proliferation SRC;GPX1;HTR1A;CYP1A1 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;SRC;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0045453| bone resorption GPR55;SRC 18050:[DB14011 DB07455] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07455|N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide GRIA2 common genes common pathways GO:0007165| signal transduction CHRNA7;GRIA2;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;GLRA3;CACNA1H;TRPV3;CHRNA7;GRIA2;TRPV2 GO:0007268| synaptic transmission VDAC1;GLRB;CACNA1G;GLRA1;GRIA2;OPRM1;OPRD1;HTR2A;GLRA3 GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;GRIA2;CHRNA7;GLRA3 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;OPRM1;GLRA3;GRIA2;SLC29A1;CHRNA7 18051:[DB14011 DB01055] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01055|Mimosine SHMT1;CCL2;TYR common genes common pathways GO:0007155| cell adhesion CCL2;CYP1B1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;TYR;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0030593| neutrophil chemotaxis PLA2G1B;CCL2 GO:0071407| cellular response to organic cyclic compound CCL2;CYP1A1;CYP1B1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;CCL2;GPR18;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0048538| thymus development SOD1;TYR GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;CCL2 GO:0051591| response to cAMP AANAT;TYR GO:0071356| cellular response to tumor necrosis factor CCL2;TRPV1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CCL2;CNR1;OPRD1;CNR2;OPRM1 GO:0051262| protein tetramerization SHMT1;HMGCR;CAT GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CCL2 GO:0001525| angiogenesis PTGS2;CCL2;CYP1B1 GO:0008152| metabolic process SMPD1;TYR;ACAT1 GO:0043524| negative regulation of neuron apoptosis SOD1;CCL2 GO:0006954| inflammatory response CCL2;TRPV1;ALOX15;IDO1;CNR2;PTGS2;ALOX5;PTGS1 GO:0051289| protein homotetramerization SHMT1;CAT;CRYZ;TRPA1;TRPV1;TRPM8 GO:0006955| immune response CNR2;OPRD1;CCL2 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB;TYR GO:0007165| signal transduction GPR18;CCL2;PPARG;SMPD1;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7 GO:0008283| cell proliferation HTR1A;GPX1;TYR;CYP1A1 GO:0033280| response to vitamin D PTGS2;TYR GO:0009411| response to UV TYR;CAT GO:0090280| positive regulation of calcium ion import TRPV3;TRPV2;CCL2 18052:[DB14011 DB07841] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07841|Geranylgeranyl diphosphate FNTA;PGGT1B;FNTB;GGPS1;FDPS;RABGGTA;RABGGTB common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A;VDAC1 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;FDPS;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0007601| visual perception RABGGTB;CYP1B1;GLRB;RABGGTA;CRYZ;GLRA1 GO:0006694| steroid biosynthetic process HMGCR;FDPS;CYP17A1 GO:0006695| cholesterol biosynthetic process GGPS1;HMGCR;FDPS GO:0008203| cholesterol metabolic process HMGCR;CAT;FDPS GO:0042127| regulation of cell proliferation PTGS2;FNTB;PTGS1 GO:0034097| response to cytokine stimulus AANAT;PTGS2;PGGT1B GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;PGGT1B;CHRNA7 GO:0008299| isoprenoid biosynthetic process GGPS1;HMGCR;FDPS GO:0045540| regulation of cholesterol biosynthetic process FDPS;HMGCR;GGPS1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR;FDPS 18053:[DB14011 DB04657] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04657|Carboxin SDHA common genes common pathways GO:0007399| nervous system development SDHA;GLRB;SMPD1 GO:0055114| oxidation-reduction process CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;SDHA;CYP3A4 GO:0022900| electron transport chain GSR;IDO1;CYP1A2;SDHA 18054:[DB14011 DB00779] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;TDO2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP2C9;CYP1A1 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0006569| tryptophan catabolic process TDO2;IDO1 GO:0019441| tryptophan catabolic process to kynurenine TDO2;IDO1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;VDAC1;TRPV4;CACNA1I;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;SLC22A6;TRPA1 GO:0051289| protein homotetramerization TDO2;CAT;CRYZ;TRPA1;TRPM8;TRPV1 GO:0098656| VDAC1;SLC22A6 18055:[DB14011 DB01086] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0034765| regulation of ion transmembrane transport CACNA1G;SCN10A;CACNA1I;CACNA1H GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;SCN10A;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3 GO:0009636| response to toxin CES1;GPX1;CAT;CYP1A1;CYP1B1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN10A GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SCN10A;CACNA1H GO:0019228| regulation of action potential in neuron CACNA1H;SCN10A;CACNA1G;CACNA1I GO:0019233| sensory perception of pain TRPV1;SCN10A;TRPA1;OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A GO:0008152| metabolic process SMPD1;CES1;ACAT1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CES1;CYP3A4;CYP1A2;CYP3A7 GO:0002027| regulation of heart rate SCN10A;CACNA1G GO:0007600| sensory perception SCN10A;TRPV2;OPRM1 GO:0086010| CACNA1H;CACNA1G;SCN10A;CACNA1I GO:0006810| transport TRPV2;ABCG2;CACNA1I;ABCB1;TRPV1;ABCC1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;SCN10A;CACNA1G;TRPA1;CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2 GO:0030855| epithelial cell differentiation CES1;PPARG;VDAC1 GO:0086016| SCN10A;CACNA1G GO:0006695| cholesterol biosynthetic process CES1;HMGCR GO:0042493| response to drug ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 18056:[DB14011 DB00858] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP19A1 GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation HTR1A;GPX1;AR;CYP1A1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;AR;PPARG;CYP1B1 GO:0007165| signal transduction AR;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1;CYP19A1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0022900| electron transport chain GSR;IDO1;CYP19A1;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0006694| steroid biosynthetic process HMGCR;CYP19A1;CYP17A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV1;TRPV4 GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport AR;TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 18057:[DB14011 DB01562] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes CYP2D6 common pathways GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0055114| oxidation-reduction process GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1 18058:[DB14011 DB04790] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04790|2,5-bis-o-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-d-glucitol PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18059:[DB14011 DB08042] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08042|N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0001525| angiogenesis CYP1B1;KDR;PTGS2 GO:0016032| viral reproduction HTR2A;KDR;VDAC1 GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;KDR GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;KDR GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;KDR;TRPV4;ALOX15 18060:[DB14011 DB08363] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08363|1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine TP53 common genes common pathways GO:0006915| apoptotic process TP53;VDAC1;GPX1 GO:0043200| response to amino acid stimulus GLRA3;GLRB;TP53 GO:0031000| response to caffeine PPARG;TP53 GO:0051262| protein tetramerization TP53;HMGCR;CAT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TP53 GO:0048511| rhythmic process TP53;PPARG;AANAT GO:0010628| positive regulation of gene expression TP53;TRPV4 GO:0007568| aging CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CYP1A1;TP53 GO:0071456| cellular response to hypoxia TP53;PTGS2;OPRD1;SLC29A1 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4;TP53 GO:0006979| response to oxidative stress TP53;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0007569| cell aging TP53;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent TP53;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;TP53 GO:0042493| response to drug ABCC1;SMPD1;TP53;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0010243| response to organic nitrogen PTGS2;TP53;TRPV1 GO:0055093| response to hyperoxia CYP1A1;TP53;CAT GO:0032526| response to retinoic acid PPARG;TP53 GO:0030308| negative regulation of cell growth TP53;PPARG GO:0042060| wound healing OPRM1;ALOX15;TP53 GO:0034097| response to cytokine stimulus PTGS2;AANAT;TP53 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;TP53 GO:0043066| negative regulation of apoptotic process TP53;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TP53;PPARG GO:0046677| response to antibiotic TP53;CYP1A1;SOD1 GO:0014070| response to organic cyclic compound TP53;TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0009411| response to UV TP53;CAT GO:0008283| cell proliferation TP53;CYP1A1;HTR1A;GPX1 GO:0008285| negative regulation of cell proliferation PPARG;TP53;CYP1B1;OPRM1;PTGS2 GO:0010332| response to gamma radiation GPX1;TP53 GO:0034644| cellular response to UV PTGS2;TP53 GO:0048662| negative regulation of smooth muscle cell proliferation TP53;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TP53;HTR2A GO:0016032| viral reproduction TP53;VDAC1;HTR2A GO:0051289| protein homotetramerization TRPM8;TRPV1;TRPA1;CRYZ;TP53;CAT GO:0006351| transcription, DNA-dependent TP53;PPARG GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;TP53 GO:0051974| negative regulation of telomerase activity PPARG;TP53 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;TP53;SMPD1;PPARG;PTGS2;CNR1;SOD1 18061:[DB14011 DB02853] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02853|D-Proline SLC36A1 common genes common pathways GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;SLC36A1 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;SLC36A1;TRPV3;CACNA1H 18062:[DB14011 DB04275] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04275|N-acetylserotonin SPR common genes common pathways GO:0006809| nitric oxide biosynthetic process CYP1B1;SPR GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;SPR;ALOX5;GPX1;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6 18063:[DB14011 DB00016] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00016|Erythropoietin EPOR common genes common pathways GO:0046697| decidualization EPOR;PTGS2 GO:0007507| heart development PPARG;EPOR GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;EPOR;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0007420| brain development ACAT1;EPOR 18064:[DB14011 DB06704] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GLRB;VDAC1;GLRA1;CACNA1G;SLC6A2 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;SLC6A2;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0006810| transport TRPV2;ABCC1;SLC6A2;ABCG2;CACNA1I;TRPV1 GO:0048265| response to pain SLC6A2;TRPA1;TRPV1 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SLC6A2;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 18065:[DB14011 DB06226] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06226|Nelipepimut-S HLA-A;HLA-A common genes common pathways GO:0002376| immune system process IDO1;HLA-A GO:0006955| immune response HLA-A;OPRD1;CNR2 GO:0016032| viral reproduction HLA-A;VDAC1;HTR2A 18066:[DB14011 DB03121] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03121|(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid PLA2G2A common genes common pathways GO:0036149| PLA2G1B;PLA2G2A GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;PLA2G2A;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0036148| PLA2G1B;PLA2G2A GO:0050729| positive regulation of inflammatory response PLA2G2A;TRPV4 GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2A GO:0036150| PLA2G1B;PLA2G2A GO:0036151| PLA2G1B;PLA2G2A GO:0006654| phosphatidic acid biosynthetic process PLA2G2A;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;PLA2G2A GO:0036152| PLA2G1B;PLA2G2A GO:0016042| lipid catabolic process PLA2G1B;PLA2G2A;DAGLA;NAPEPLD GO:0070374| positive regulation of ERK1 and ERK2 cascade PLA2G2A;ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G2A;PLA2G1B 18067:[DB14011 DB03251] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03251|RWJ-51084 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18068:[DB14011 DB07757] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;ESR2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;ESR2 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;ESR2;PLA2G1B;CACNA1I GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG GO:0006351| transcription, DNA-dependent ESR2;PPARG 18069:[DB14011 DB04367] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04367|Debromohymenialdisine TNK2;CLK1 common genes common pathways GO:0045087| innate immune response TNK2;PPARG GO:0042127| regulation of cell proliferation PTGS1;TNK2;PTGS2 GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;TNK2;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0008283| cell proliferation GPX1;HTR1A;CLK1;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;TNK2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TNK2;HTR2A 18070:[DB14011 DB09322] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09322|Zinc sulfate ALPPL2 common genes common pathways GO:0008152| metabolic process SMPD1;ALPPL2;ACAT1 18071:[DB14011 DB08553] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways GO:0048538| thymus development BRAF;SOD1 GO:0015758| glucose transport PLA2G1B;BRAF GO:0010628| positive regulation of gene expression TRPV4;BRAF GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;BRAF;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0051591| response to cAMP AANAT;BRAF GO:0043066| negative regulation of apoptotic process BRAF;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;BRAF GO:0033138| positive regulation of peptidyl-serine phosphorylation BRAF;OPRD1;PTGS2 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CACNA1I;BRAF;PLA2G1B;SMPD1;PPARG;GPR18 GO:0043434| response to peptide hormone stimulus TRPV1;BRAF GO:0051291| protein heterooligomerization GLRB;BRAF;GLRA1 GO:1990090| BRAF;TRPV1 GO:0035556| intracellular signal transduction BRAF;PLA2G1B GO:0071277| cellular response to calcium ion ALOX15;BRAF GO:0008542| visual learning BRAF;HMGCR GO:0043524| negative regulation of neuron apoptosis SOD1;BRAF 18072:[DB14011 DB07544] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;BCAT1 GO:0008283| cell proliferation GPX1;BCAT1;HTR1A;CYP1A1 GO:0009083| branched chain family amino acid catabolic process BCAT1;ACAT1 18073:[DB14011 DB04178] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04178|Di-Stearoyl-3-Sn-Phosphatidylcholine BPI;SLC25A4 common genes common pathways GO:0050796| regulation of insulin secretion SLC25A4;CNR1 GO:0061844| PLA2G1B;BPI GO:0006955| immune response BPI;OPRD1;CNR2 GO:0016032| viral reproduction HTR2A;SLC25A4;VDAC1 GO:0006810| transport TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1;SLC25A4 GO:0032720| negative regulation of tumor necrosis factor production GPR18;BPI;CHRNA7 GO:0055085| transmembrane transport ABCC1;SLC25A4;CACNA1G;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0043312| neutrophil degranulation BPI;ALOX5;CAT GO:0019731| antibacterial humoral response BPI;PLA2G1B 18074:[DB14011 DB00142] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0045471| response to ethanol CAT;GRIN2A;GRIN1;OPRM1;HMGCR;GRIN2B;SOD1;CNR1;ABAT;GOT2;GRIN3A GO:0045776| negative regulation of blood pressure CNR1;ABAT GO:0001525| angiogenesis ENPEP;PTGS2;CYP1B1 GO:0019233| sensory perception of pain OPRD1;CNR2;PTGS2;GRIN1;OPRM1;HTR2A;CNR1;GRIN2A;TRPA1;TRPV1;GRM1 GO:0001889| liver development CYP1A1;ASNS;FPGS;ACAT1 GO:0030431| sleep HTR2A;GRIN2A;SLC29A1;CACNA1I GO:0019228| regulation of action potential in neuron CACNA1G;CACNA1I;CACNA1H;GRIK2 GO:0007399| nervous system development SMPD1;SLC1A2;GLRB;GRIK1 GO:0071260| cellular response to mechanical stimulus PTGS2;GCLC GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GRIN2A;GRIA1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;SLC16A1;NAAA;GPX1;PTGS1;PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;GRIN2A;GRIN1;PTGS2;CNR1;SOD1 GO:0048148| behavioral response to cocaine ABAT;HTR2A GO:0042428| serotonin metabolic process HTR1A;GRIN2A GO:0008152| metabolic process BCAT2;SMPD1;AASS;ALDH18A1;FTCD;EPRS;ACAT1;BCAT1;FOLH1 GO:0042136| neurotransmitter biosynthetic process GAD2;DAGLA;GAD1 GO:0043524| negative regulation of neuron apoptosis GCLC;GRIN1;GRIK2;SOD1;GCLM GO:0007268| synaptic transmission GRIN2A;GRM4;GRIK1;SLC1A6;GRIA2;GLRA3;HTR2A;GRIN2B;GLS;GRIK2;OPRD1;OPRM1;GRM1;SLC1A2;SLC1A1;GRIK5;GAD2;SLC1A3;GAD1;GRIK4;GRIA1;GRM7;VDAC1;GLRB;GLRA1;CACNA1G GO:0031667| response to nutrient levels SOD1;ASNS GO:1902476| GLRA1;GLRB;SLC1A1;SLC1A3;GLRA3 GO:0051924| regulation of calcium ion transport OPRD1;GRIN3B GO:0008542| visual learning GRIN2A;GRIN1;HMGCR GO:0014047| glutamate secretion SLC1A6;GLS;TRPV1;SLC1A3;SLC1A1;SLC1A2;SLC1A7;GLS2 GO:0009408| response to heat SOD1;TRPV3;GCLC;TRPV2;TRPV1 GO:0051289| protein homotetramerization GLS;CAT;TRPA1;CRYZ;TRPM8;TRPV1 GO:0006816| calcium ion transport CACNA1G;GRIN3A;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1H;GRIN1;TRPV3;TRPV2;CHRNA7;GRIN2A GO:0001964| startle response GRIN2A;GRIN1;GRIN2D;GLRB;GLRA1 GO:0032869| cellular response to insulin stimulus GOT1;GCLC;PPARG;PLA2G1B GO:0043576| regulation of respiratory gaseous exchange GRIN1;GLRA1 GO:0050796| regulation of insulin secretion SLC16A1;CNR1 GO:0007613| memory PTGS2;GRIN1;HTR2A;CNR1;CHRNA7;GRIN2A GO:0007601| visual perception GRM8;CRYZ;GLRA1;CYP1B1;GLRB GO:0022008| neurogenesis DAGLA;GRIN2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway GRM7;GRM8;OPRM1;OPRD1 GO:0051384| response to glucocorticoid stimulus TAT;PTGS2;GOT1 GO:0072593| reactive oxygen species metabolic process GLS2;SOD1 GO:0001975| response to amphetamine GRIN2A;GRIN1;CNR2;SOD1 GO:0045454| cell redox homeostasis GSR;GPX1;GCLC GO:0009725| response to hormone stimulus GCLC;ACAT1 GO:0007420| brain development SLC7A11;FPGS;ACAT1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;GRIA2;CHRNA7;GRM4;GRM8;SMPD1;GPR18;PPARG;GRIA1;PLA2G1B;GRM7;CACNA1I;GRM1 GO:0065009| regulation of molecular function TRPV1;GRM7;GRIN2C;GRIN2A;GRIN2D;GRIN1;GRIN2B GO:0070588| calcium ion transmembrane transport CACNA1G;GRIN3A;TRPA1;TRPV1;TRPV4;GRIN3B;CACNA1I;TRPM8;CACNA1H;OPRM1;TRPV3;TRPV2;CHRNA7 GO:0032870| cellular response to hormone stimulus CACNA1H;ASNS GO:1900273| GRIN2A;CHRNA7 GO:0008344| adult locomotory behavior GRIN2D;GRIN1;OPRD1 GO:0008283| cell proliferation CYP1A1;GPX1;FPGS;BCAT1;GLUL;ENPEP;HTR1A GO:0006811| ion transport SLC1A6;GRIA2;TRPV2;GRIK1;GRIN2A;CHRNA7;GRIN2D;GRIN1;GRIA3;CACNA1H;TRPV3;GRIN2B;GRIK2;GLRA3;VDAC1;CACNA1I;GRIN3B;TRPV4;GLRB;TRPV1;GRIK4;GRIA1;SLC1A2;SLC1A1;GRIK5;SLC1A3;TRPM8;CACNA1G;GRIA4;GRIN2C;GRIK3;SLC1A7;GRID1;GRIN3A;SLC25A18;SLC25A22;GLRA1;TRPA1;GRID2 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;FPGS GO:0051930| regulation of sensory perception of pain GRM1;OPRD1;OPRM1;GRIN2D;GRIN2A GO:0014070| response to organic cyclic compound TRPA1;TAT;PPARG;CYP1A1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0009636| response to toxin GPX1;CAT;SLC7A11;ASNS;CYP1B1;CYP1A1 GO:0001662| behavioral fear response VDAC1;GRM7;HTR1A;GRIK2 GO:0006812| cation transport GRIN1;TRPM8 GO:0007584| response to nutrient CNR1;HMGCR;GCLC;PPARG;GCLM GO:0014823| response to activity CAT;GCLC;GCLM GO:0098656| VDAC1;SLC1A2 GO:0006749| glutathione metabolic process OPLAH;SOD1;GPX1;GCLC;GCLM;GSR GO:0050896| response to stimulus GRM8;GRM7;TRPM8;TRPA1 GO:0051966| regulation of synaptic transmission, glutamatergic GRM1;GRM7;CNR1;GRM4;GRM8;GRIK1 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIA3;GRIN1;GRIN2D;OPRM1;GLRA3;GRIN2B;GRIK2;SLC29A1;GRIK1;GRIA2;GRIN2A;CHRNA7;GRIK3;GRIA4;GRIN2C;GLRA1;GRID2;GRIN3A;GRID1;GRIK4;GRIA1;GLRB;GRIN3B;TRPV1;GRIK5 GO:0007269| neurotransmitter secretion NAAA;GRM4;GAD1;GAD2 GO:0071333| cellular response to glucose stimulus GRIK5;GCLM;GCLC;SLC29A1 GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B;GRIN1 GO:0007612| learning PTGS2;GRIN1;GRIN2A;VDAC1 GO:0009410| response to xenobiotic stimulus GPX1;GCLC GO:0007611| learning or memory GRIN1;GRIN2B;CNR1;GRIN2A;CHRNA7 GO:0043523| regulation of neuron apoptosis GRID2;GRIN1;GPX1;GRM4 GO:0007626| locomotory behavior ABAT;GRM1;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;GRIN1 GO:0033602| negative regulation of dopamine secretion ABAT;CNR1 GO:0046677| response to antibiotic SOD1;SLC1A3;CYP1A1 GO:0070207| protein homotrimerization TRPM8;SLC1A2 GO:0009612| response to mechanical stimulus ASNS;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process ASNS;SOD1;PTGS2;HMGCR;CAT;GCLC;GPX1 GO:0055114| oxidation-reduction process AASS;CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALDH18A1;ALOX15;CYP3A5;CYP17A1;HMGCR;GLUD1;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GLUD2;GPX1;ALOX5;PTGS1;CAT GO:0046685| response to arsenic-containing substance CYP1A1;GCLC GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;GRIN2A;GCLM;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;SLC1A3;ABCG2;GAD2;SLC1A2;PFAS;ABAT;GAD1 GO:0050905| neuromuscular process GRIN1;GLRA1;GLRB GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1B1;CYP1A1 GO:0032094| response to food OPRM1;SLC16A1;CYP1A1 GO:0035640| exploration behavior HTR1A;ABAT GO:0035094| response to nicotine CHRNA7;SLC7A11;CNR1;ABAT GO:0009083| branched chain family amino acid catabolic process BCAT1;ACAT1;BCAT2 GO:0051967| negative regulation of synaptic transmission, glutamatergic GRIK2;HTR2A;GRIK3 GO:0043278| response to morphine CNR1;OPRM1;GRIN1 GO:0006810| transport ABCG2;GRIK4;CACNA1I;TRPV1;GRID2;ABCC1;GRIA4;GRIN2C;GRIN2A;GRIK1;TRPV2;GRIN2B;GRIK2;GRIA3 GO:0007568| aging NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT;GCLC;GCLM;CYP1A1;ABAT GO:0007186| G-protein coupled receptor signaling pathway GRM1;GRM7;PPARG;GPR18;GRM8;GRM4;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0006569| tryptophan catabolic process IDO1;AADAT GO:0009611| response to wounding SLC1A3;SLC1A2;GRIN2C;CYP1A1;GPX1;GRIN2A GO:0007605| sensory perception of sound GRM7;SLC1A3;GPX1;SOD1 GO:0007216| metabotropic glutamate receptor signaling pathway DAGLA;GRM1;GRIK3 GO:0031100| organ regeneration PPARG;FPGS GO:0042593| glucose homeostasis SLC16A1;CNR1;TRPV4;PPARG GO:0051260| protein homooligomerization SLC1A1;GLRA1;ACAT1;GLRA3;GLUL GO:0042391| regulation of membrane potential GRIN2A;SLC1A6;GRIK2;CACNA1H;GRIN1;GRIK5;GLRB;GLRA1;GRIN2C;CACNA1G;GRIK3 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;GPR12;HTR2A;GRIK2;GRIN1 GO:0006979| response to oxidative stress GCLM;TAT;PTGS2;SLC7A11;SOD1;GPX1;PTGS1;CAT;GCLC GO:0055085| transmembrane transport GRIK2;SLC16A10;TRPV3;CACNA1H;SLC16A1;GRIK1;TRPV2;SLC25A18;SLC25A22;TRPA1;SLC1A7;GRIK3;ABCC1;CACNA1G;TRPM8;GRIK5;ABCG2;GRIK4;VDAC1;CACNA1I;TRPV4;TRPV1 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLS;GLRA1 GO:0006550| isoleucine catabolic process ACAT1;BCAT2 GO:0042220| response to cocaine ABAT;SMPD1;OPRM1;CNR1 GO:0000187| activation of MAPK activity GRM4;CHRNA7;SOD1;GRM1;PLA2G1B GO:0046686| response to cadmium ion CAT;GCLC GO:0043200| response to amino acid stimulus GLRB;SLC1A2;GLRA3;ASNS GO:0034220| ion transmembrane transport GRIA3;GRIK2;GLRA3;GRIA2;GRIK1;CHRNA7;GRIA4;GRIK3;GRID1;GRIN3A;GRID2;GLRA1;TRPA1;TRPV1;GLRB;GRIN3B;GRIA1;GRIK4;GRIK5 GO:0019441| tryptophan catabolic process to kynurenine IDO1;AADAT GO:0009416| response to light stimulus SLC1A3;SLC1A2;AANAT;ASNS GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN1 GO:0045892| negative regulation of transcription, DNA-dependent GCLC;PPARG GO:0060080| regulation of inhibitory postsynaptic membrane potential GRIK2;GLRA1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GRM1;GPR18 GO:0051262| protein tetramerization AASS;HMGCR;CAT GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;GLUL GO:0001666| response to hypoxia ABAT;CYP1A1;CAT;CHRNA7 18075:[DB14011 DB04147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04147|Lauryl Dimethylamine-N-Oxide MAOB;tesB;ctaC;IGHV3-23;DSTN;RHO;cycA;NFE2L1;PMP2;tonB;CFL1;amtB;DHODH;traF;MAOB common genes common pathways GO:0007595| lactation SLC29A1;DHODH GO:0006954| inflammatory response TRPV1;IDO1;NFE2L1;ALOX15;ALOX5;PTGS1;CNR2;PTGS2 GO:0006955| immune response CNR2;OPRD1;IGHV3-23 GO:0007565| female pregnancy IDO1;DHODH GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;DHODH;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0045471| response to ethanol MAOB;OPRM1;HMGCR;SOD1;CNR1;CAT GO:0006351| transcription, DNA-dependent PPARG;NFE2L1 GO:0006357| regulation of transcription from RNA polymerase II promoter NFE2L1;PPARG GO:0050896| response to stimulus TRPM8;RHO;TRPA1 GO:0055088| lipid homeostasis NFE2L1;PPARG GO:0001523| retinoid metabolic process NAPEPLD;RHO GO:0010269| response to selenium ion MAOB;GPX1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;DHODH;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;MAOB;CYP1A1 GO:0007165| signal transduction CACNA1I;PLA2G1B;RHO;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0007601| visual perception GLRB;CYP1B1;RHO;GLRA1;CRYZ GO:0045454| cell redox homeostasis NFE2L1;GSR;GPX1 GO:0007015| actin filament organization TRPV4;PLA2G1B;CFL1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;MAOB;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;DHODH;CAT;ALOX5;PTGS1;GPX1 GO:0042493| response to drug CAT;DHODH;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;CYP1A1;PPARG;TRPA1;MAOB;SMPD1;ABCC1 GO:0006355| regulation of transcription, DNA-dependent NFE2L1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NFE2L1;PPARG GO:0022900| electron transport chain MAOB;GSR;IDO1;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;NFE2L1 GO:0045087| innate immune response IGHV3-23;PPARG GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NFE2L1;PLA2G1B GO:0009615| response to virus CYP1A1;CFL1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CFL1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;CFL1;SOD1;GPX1;CAT GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;NFE2L1;GSR GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;CYP1A1;MAOB;IDO1 GO:0009416| response to light stimulus AANAT;RHO GO:0031000| response to caffeine PPARG;DHODH GO:0043200| response to amino acid stimulus GLRA3;CFL1;GLRB GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;MAOB;SOD1;CYP1A2 GO:0002376| immune system process IGHV3-23;IDO1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;RHO;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 18076:[DB14011 DB07444] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;DAPK1 GO:0006915| apoptotic process VDAC1;DAPK1;GPX1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;DAPK1 GO:0035556| intracellular signal transduction DAPK1;PLA2G1B GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;DAPK1;HTR2A;OPRM1;CNR2;OPRD1 GO:1902042| GPX1;DAPK1 18077:[DB14011 DB11842] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11842|Angiotensin II AGTR1 common genes common pathways GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;AGTR1;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0050729| positive regulation of inflammatory response AGTR1;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;AGTR1;TRPV1;TRPV4 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;AGTR1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger AGTR1;GPR55;GPR18 GO:0001822| kidney development AGTR1;CAT GO:0042127| regulation of cell proliferation PTGS2;PTGS1;AGTR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGTR1;HTR2A;OPRM1;OPRD1 GO:0060326| cell chemotaxis ABCC1;AGTR1 18078:[DB14011 DB06964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06964|5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;PTGS2;OPRM1 GO:0009409| response to cold TRPM8;HSP90AA1;PPARG;TRPA1 GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;SOD1;TRPV3 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;HSP90AA1;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 18079:[DB14011 DB13173] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IGF2R;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0001889| liver development ACAT1;CYP1A1;IGF2R GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;IGF2R;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0009791| post-embryonic development IGF2R;CYP1A2 GO:0043312| neutrophil degranulation IGF2R;CAT;ALOX5 GO:0032526| response to retinoic acid IGF2R;PPARG GO:0031100| organ regeneration IGF2R;PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;IGF2R;GPR18;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0007283| spermatogenesis SOD1;CNR1;IGF2R 18080:[DB14011 DB06680] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06680|Asoprisnil PGR common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;PGR;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7 GO:0043401| steroid hormone mediated signaling pathway PPARG;PGR GO:0006351| transcription, DNA-dependent PPARG;PGR GO:0010629| negative regulation of gene expression OPRD1;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;PLA2G1B;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;PGR GO:0006367| transcription initiation from RNA polymerase II promoter PGR;PPARG 18081:[DB14011 DB05120] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05120|AT1391 INSR common genes common pathways GO:0000187| activation of MAPK activity SOD1;CHRNA7;INSR;PLA2G1B GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;INSR;OPRM1;PTGS2 GO:0042593| glucose homeostasis CNR1;PPARG;INSR;TRPV4 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;INSR;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;INSR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG GO:0006355| regulation of transcription, DNA-dependent INSR;PPARG GO:0008284| positive regulation of cell proliferation INSR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0007612| learning INSR;VDAC1;PTGS2 GO:0045740| positive regulation of DNA replication PLA2G1B;INSR GO:0007613| memory INSR;HTR2A;CNR1;PTGS2;CHRNA7 GO:0032869| cellular response to insulin stimulus INSR;PPARG;PLA2G1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;INSR GO:0035556| intracellular signal transduction INSR;PLA2G1B GO:0045821| positive regulation of glycolysis HTR2A;INSR 18082:[DB14011 DB09207] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0008542| visual learning HMGCR;DRD3;DRD2 GO:0001964| startle response GLRA1;GLRB;DRD2 GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;DRD3;DRD2 GO:0045776| negative regulation of blood pressure CNR1;DRD2;DRD3 GO:0048678| response to axon injury SOD1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0001659| temperature homeostasis DRD2;TRPV1;HTR2A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0035556| intracellular signal transduction PLA2G1B;DRD2 GO:0048148| behavioral response to cocaine HTR2A;DRD3;DRD2 GO:0014854| response to inactivity DRD2;CAT GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0009636| response to toxin CYP1B1;DRD2;CYP1A1;GPX1;CAT GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;DRD2;CYP1B1 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0040014| regulation of multicellular organism growth DRD3;SOD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;DRD3;CNR1;HMGCR GO:0001975| response to amphetamine DRD3;DRD2;SOD1;CNR2 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;DRD3;PPARG;PLA2G1B;DRD2;CACNA1I GO:0050482| arachidonic acid secretion DRD3;DRD2;PLA2G1B GO:1900273| DRD2;CHRNA7 GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;DRD2;CYP1A1;PPARG;TRPA1;DRD3;SMPD1;ABCC1 GO:0043278| response to morphine DRD2;DRD3;OPRM1;CNR1 GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;DRD2;GLRB;TRPV1;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0007612| learning DRD3;VDAC1;PTGS2 GO:0007611| learning or memory CNR1;CHRNA7;DRD3 GO:0007628| adult walking behavior GLRA1;GLRB;DRD2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;PPARG;TRPV4;TRPV1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0008284| positive regulation of cell proliferation DRD3;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;PPARG;DRD2;PLA2G1B GO:0007626| locomotory behavior DRD3;DRD2;OPRM1;SOD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD3 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;DRD2;ALOX15 GO:0042220| response to cocaine SMPD1;DRD3;DRD2;OPRM1;CNR1 GO:0009416| response to light stimulus AANAT;DRD2 GO:0014059| regulation of dopamine secretion HTR2A;DRD2;DRD3 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD2;GPR18;GPR55 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DRD2 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;DRD2;TRPV1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;DRD2;DRD3;GPR18;PPARG GO:0006874| cellular calcium ion homeostasis DRD3;DRD2;TRPV4;TRPM8;HTR2A;GPR12;CHRNA7 18083:[DB14011 DB04094] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;FKBP1A;TRPV1;CACNA1I;TRPV4;TRPV3;CACNA1H;OPRM1;CHRNA7;TRPV2 GO:0031000| response to caffeine FKBP1A;PPARG GO:1902991| FKBP1A;CHRNA7 GO:0006936| muscle contraction FKBP1A;GLRA1;CACNA1H GO:0051209| release of sequestered calcium ion into cytosol HTR2A;FKBP1A;TRPV1;TRPA1 18084:[DB14011 DB04719] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04719|DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE CSNK2A1 common genes common pathways GO:0006915| apoptotic process GPX1;CSNK2A1;VDAC1 GO:0048511| rhythmic process PPARG;CSNK2A1;AANAT GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CSNK2A1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;CSNK2A1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CSNK2A1;OPRM1;CNR2;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;CSNK2A1 GO:0006351| transcription, DNA-dependent CSNK2A1;PPARG 18085:[DB14011 DB00198] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CES1;CYP3A4;PTGS1 GO:0008152| metabolic process SMPD1;NEU1;CES1;NEU2;ACAT1 GO:0006629| lipid metabolic process HMGCR;NEU2;CYP1A2;PTGS2;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;DAGLA;CYP2D6;NEU1;ALOX15 GO:0098656| SLC22A8;VDAC1 GO:0009636| response to toxin CYP1A1;CYP1B1;CES1;SLC22A8;GPX1;CAT GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;ABCC4;ACAT1;AANAT GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;SLC22A8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1;SLC15A1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;ABCC4 GO:0010243| response to organic nitrogen ABCC4;PTGS2;TRPV1 GO:0099133| ABCC4;ABCC1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCC4;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;GPX1;PTGS1;ABCC4;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1 GO:0002576| platelet degranulation SOD1;ABCC4 GO:0043312| neutrophil degranulation CAT;ALOX5;NEU1 GO:0006695| cholesterol biosynthetic process CES1;HMGCR GO:0010033| response to organic substance ABCC4;PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1 GO:0016042| lipid catabolic process NAPEPLD;NEU2;DAGLA;NEU1;PLA2G1B GO:0030855| epithelial cell differentiation VDAC1;PPARG;CES1 GO:0055085| transmembrane transport TRPV2;ABCC4;SLC22A8;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;SLC15A1;TRPA1;CACNA1G;ABCC1 GO:0006687| glycosphingolipid metabolic process NEU2;NEU1;SMPD1 GO:0006810| transport TRPV2;ABCC1;SLC15A1;CACNA1I;TRPV1;ABCG2 18086:[DB14011 DB08871] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0007569| cell aging BCL2;SOD1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2;BCL2 GO:0035094| response to nicotine BCL2;CNR1;CHRNA7 GO:0007015| actin filament organization BCL2;PLA2G1B;TRPV4 GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0034097| response to cytokine stimulus AANAT;PTGS2;BCL2 GO:0043066| negative regulation of apoptotic process SOD1;BCL2;HMGCR;PTGS2;CAT;GPX1 GO:0001822| kidney development BCL2;CAT GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;BCL2;HMGCR;HTR1A;HTR2A GO:0001541| ovarian follicle development BCL2;SOD1 GO:0006915| apoptotic process GPX1;BCL2;VDAC1 GO:0055085| transmembrane transport TRPV2;CACNA1H;BCL2;TRPV3;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0001657| ureteric bud development CAT;BCL2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;BCL2;PTGS2 GO:0010468| regulation of gene expression BCL2;CYP1A2 GO:0043085| positive regulation of catalytic activity BCL2;SOD1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;BCL2;PTGS2;SOD1 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;BCL2;CHRNA7;TRPM8;TRPV4 GO:0048538| thymus development SOD1;BCL2 GO:0007565| female pregnancy IDO1;BCL2 GO:0008631| induction of apoptosis by oxidative stress BCL2;GPX1;CYP1B1 GO:0043524| negative regulation of neuron apoptosis BCL2;SOD1 GO:0051924| regulation of calcium ion transport OPRD1;BCL2 GO:0030217| T cell differentiation BCL2;GPR18 GO:0001503| ossification BCL2;ALOX15 GO:0042542| response to hydrogen peroxide SOD1;BCL2;CAT;GPX1;TRPA1 GO:0009314| response to radiation PTGS2;OPRM1;BCL2;CAT GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;BCL2 GO:0009636| response to toxin GPX1;CAT;BCL2;CYP1B1;CYP1A1 GO:0008283| cell proliferation CYP1A1;HTR1A;BCL2;GPX1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;BCL2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;BCL2 GO:0001662| behavioral fear response VDAC1;BCL2;HTR1A GO:0030336| negative regulation of cell migration CYP1B1;BCL2 GO:0009791| post-embryonic development CYP1A2;BCL2 GO:0072593| reactive oxygen species metabolic process SOD1;BCL2 GO:0051384| response to glucocorticoid stimulus BCL2;PTGS2 GO:0010332| response to gamma radiation BCL2;GPX1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;BCL2 18087:[DB14011 DB04462] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04462|Tetrabromo-2-Benzotriazole CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1;GPX1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CSNK2A1;OPRM1;CNR2;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;CSNK2A1;PTGS2 GO:0006915| apoptotic process VDAC1;CSNK2A1;GPX1 GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG 18088:[DB14011 DB05996] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways GO:0001934| positive regulation of protein phosphorylation GPNMB;CHRNA7 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;GPNMB;PPARG;CYP1B1 GO:0001649| osteoblast differentiation GPNMB;CAT GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;GPNMB;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0007155| cell adhesion CYP1B1;GPNMB GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;GPNMB;HMGCR;ALOX15;TRPV4 GO:0042130| negative regulation of T cell proliferation GPNMB;IDO1 GO:0030282| bone mineralization ALOX15;PTGS2;GPNMB GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPNMB;GPR18 18089:[DB14011 DB08015] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08015|(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;MAPK10 GO:0048511| rhythmic process AANAT;PPARG;MAPK10 GO:0009416| response to light stimulus MAPK10;AANAT GO:0000187| activation of MAPK activity PLA2G1B;MAPK10;SOD1;CHRNA7 GO:0042752| regulation of circadian rhythm PPARG;MAPK10 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;MAPK10;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 18090:[DB14011 DB04197] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04197|Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0009611| response to wounding CYP1A1;ARG1;GPX1 GO:0007568| aging ARG1;CAT;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CYP1A1 GO:0002376| immune system process ARG1;IDO1 GO:0046686| response to cadmium ion CAT;ARG1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ARG1 GO:0042130| negative regulation of T cell proliferation IDO1;ARG1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;ARG1;CYP1A1;IDO1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E ARG1;CAT GO:0030324| lung development CYP1A2;ARG1 GO:0070207| protein homotrimerization TRPM8;ARG1 GO:0045087| innate immune response PPARG;ARG1 GO:0043312| neutrophil degranulation ALOX5;ARG1;CAT GO:0042493| response to drug CAT;ARG1;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0010042| response to manganese ion PTGS2;ARG1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT;ARG1 GO:0043434| response to peptide hormone stimulus TRPV1;ARG1 GO:0010269| response to selenium ion GPX1;ARG1 GO:0010043| response to zinc ion AANAT;ARG1 GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;ARG1 GO:0048678| response to axon injury SOD1;ARG1 GO:0001889| liver development CYP1A1;ACAT1;ARG1 GO:0009635| response to herbicide CYP1A1;ARG1 GO:0007565| female pregnancy IDO1;ARG1 18091:[DB14011 DB13894] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13894|Agkistrodon piscivorus antivenin PLA2G10 common genes common pathways GO:0006654| phosphatidic acid biosynthetic process PLA2G10;PLA2G1B GO:0036151| PLA2G10;PLA2G1B GO:0019369| arachidonic acid metabolic process PLA2G10;FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0036152| PLA2G10;PLA2G1B GO:0006644| phospholipid metabolic process PLA2G10;NAPEPLD;PLA2G1B GO:0016042| lipid catabolic process DAGLA;PLA2G1B;NAPEPLD;PLA2G10 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;PLA2G10;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0036148| PLA2G10;PLA2G1B GO:0036149| PLA2G10;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G10;PLA2G1B GO:0036150| PLA2G10;PLA2G1B 18092:[DB14011 DB05915] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05915|MYO-029 MSTN common genes common pathways GO:0043403| skeletal muscle tissue regeneration MSTN;GPX1 GO:0045471| response to ethanol CAT;MSTN;OPRM1;HMGCR;CNR1;SOD1 GO:0009408| response to heat TRPV1;SOD1;TRPV3;MSTN;TRPV2 GO:0051384| response to glucocorticoid stimulus PTGS2;MSTN GO:0043627| response to estrogen stimulus PPARG;MSTN GO:0045893| positive regulation of transcription, DNA-dependent MSTN;PPARG GO:0007517| muscle organ development MSTN;CACNA1H GO:0046716| muscle cell homeostasis SOD1;MSTN 18093:[DB14011 DB07366] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07366|2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 18094:[DB14011 DB03381] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03381|Hexadecanal RHO;DBI common genes common pathways GO:0050896| response to stimulus TRPA1;RHO;TRPM8 GO:0001523| retinoid metabolic process RHO;NAPEPLD GO:0007601| visual perception GLRA1;CRYZ;RHO;GLRB;CYP1B1 GO:0007165| signal transduction PPARG;GPR18;RHO;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0009416| response to light stimulus AANAT;RHO GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PPARG;GPR18;RHO GO:0036151| DBI;PLA2G1B 18095:[DB14011 DB07981] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes PTGS1 common pathways GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;TRPV1;ALOX15;IDO1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 18096:[DB14011 DB09285] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes ALOX5;PTGS2 common pathways GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:2001300| ALOX5 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;TBXA2R GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0006936| muscle contraction GLRA1;LTB4R;CACNA1H GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:1902219| PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;LTB4R;OPRM1;TBXA2R GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0007568| aging PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT;CYP1A1 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0009750| response to fructose stimulus PTGS2 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;TBXA2R;CAT GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;OPRD1;LTB4R;OPRM1;GLRA3 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0043312| neutrophil degranulation ALOX5;CAT GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;TBXA2R;CYP1A1;IDO1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LTB4R;OPRM1;OPRD1;HTR2A GO:0071284| cellular response to lead ion PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TBXA2R GO:0007584| response to nutrient PPARG;TBXA2R;HMGCR;CNR1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0045777| positive regulation of blood pressure CNR1;TBXA2R GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;TBXA2R GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;TBXA2R;CHRNA7;OPRM1;CNR2;LTB4R;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0065009| regulation of molecular function TRPV1;TBXA2R GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;TBXA2R;OPRM1;HTR2A GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0006954| inflammatory response PTGS1;ALOX5;TBXA2R;PTGS2;LTB4R;CNR2;TRPV1;ALOX15;IDO1 GO:0010942| positive regulation of cell death PTGS2 GO:0006955| immune response OPRD1;CNR2;LTB4R GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:1990776| PTGS2 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0045471| response to ethanol CAT;TBXA2R;SOD1;CNR1;HMGCR;OPRM1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain CNR1;HTR2A;PTGS2;CNR2;OPRM1;OPRD1;TRPA1;TRPV1 18097:[DB14011 DB03048] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;GPX1;ALOX5;PTGS1;DPYD;CRYZ;CYP2C9;CYP1A1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1 18098:[DB14011 DB01210] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes CYP2D6 common pathways GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process CYP2D6;DAGLA;ALOX15;CYP1B1;FAAH GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ADRB2 GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1;ADRB2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;ADRB1;CNR1;GPR12;HTR2A;ADRB2;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0001659| temperature homeostasis HTR2A;GPX1;TRPV1;ADRB1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB2;CNR1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0009409| response to cold ADRB2;TRPM8;ADRB1;PPARG;TRPA1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;ADRB2 GO:0050873| brown fat cell differentiation PTGS2;ADRB2;ADRB1 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0007165| signal transduction PLA2G1B;CACNA1I;ADRB1;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;ADRB2;HTR1A;GPR55 GO:0045453| bone resorption GPR55;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 18099:[DB14011 DB02556] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:0043627| response to estrogen stimulus CRH;PPARG GO:0090280| positive regulation of calcium ion import TRPV2;TRPV3;CRH GO:0043950| positive regulation of cAMP-mediated signaling CRH;OPRM1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;CRH;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0051412| response to corticosterone stimulus AANAT;CRH GO:0007565| female pregnancy CRH;IDO1 GO:0001934| positive regulation of protein phosphorylation CRH;CHRNA7 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;VDAC1;GLRB;GLRA1;CRH;CACNA1G GO:0010629| negative regulation of gene expression OPRD1;CRH GO:0010942| positive regulation of cell death CRH;PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;CRH;ALOX5;PTGS1;PTGS2;CNR2 GO:0045471| response to ethanol CRH;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0007399| nervous system development SMPD1;GLRB;SLC7A5 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;CRH GO:0055085| transmembrane transport TRPV3;SLC16A10;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;CRH GO:0014062| regulation of serotonin secretion CRH;HTR1A GO:0010628| positive regulation of gene expression CRH;TRPV4 GO:0006810| transport ABCC1;CACNA1I;TRPV1;SLC7A5;ABCG2;TRPV2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;PPARG;GPR18;CRH GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CRH;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5 GO:0006704| glucocorticoid biosynthetic process CYP17A1;CRH GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;CRH;SMPD1;ABCG2 GO:0048265| response to pain TRPV1;TRPA1;CRH GO:0030324| lung development CYP1A2;CRH GO:0007611| learning or memory CRH;CHRNA7;CNR1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;CRH GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;CRH 18100:[DB14011 DB06217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes CYP2D6 common pathways GO:0086010| KCNH2;CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;GPX1;NAAA;PTGS1;PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0002027| regulation of heart rate SCN5A;CACNA1G GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;TRPA1;KCNA5 GO:0051100| negative regulation of binding CYP2D6 GO:0035725| sodium ion transmembrane transport SCN5A;CACNA1H;CACNA1I;CACNA1G GO:0019228| regulation of action potential in neuron CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0071277| cellular response to calcium ion ALOX15;SCN5A GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0086091| KCNH2;SCN5A;KCND3;CACNA1G;KCNA5 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0086046| CACNA1G;SCN5A GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN5A;CACNA1G GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0043267| negative regulation of potassium ion transport KCNA5;HTR2A GO:0086045| CACNA1G;SCN5A GO:0006811| ion transport TRPV2;CHRNA7;KCND3;SCN5A;TRPV3;KCNH2;CACNA1H;GLRA3;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;KCNA5;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0065009| regulation of molecular function KCNA5;TRPV1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0034765| regulation of ion transmembrane transport CACNA1I;KCNA5;CACNA1G;KCND3;SCN5A;KCNH2;CACNA1H GO:0050796| regulation of insulin secretion CNR1;KCNA5 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:1900087| CYP1A1;KCNA5 GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;FAAH GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055093| response to hyperoxia CYP1A1;KCNA5;CAT GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP1A1;CYP2C9;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0009612| response to mechanical stimulus PPARG;TRPV4;KCNA5 GO:0086015| SCN5A;CACNA1G GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;KCNA5 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0086016| CACNA1G;SCN5A GO:0010033| response to organic substance KCNA5;CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;KCNA5 GO:0055085| transmembrane transport TRPV2;SCN5A;KCND3;TRPV3;KCNH2;CACNA1H;VDAC1;TRPV4;CACNA1I;TRPV1;KCNA5;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0086002| SCN5A;CACNA1G GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;GLRA1;CACNA1G;KCNA5;GLRB GO:0051260| protein homooligomerization KCNA5;GLRA1;KCND3;ACAT1;GLRA3 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 18101:[DB14011 DB02570] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02570|PD150606 CAPNS1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPNS1;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 18102:[DB14011 DB07960] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;NEU2;CYP1A2;PTGS2;GPX1;NAAA;PTGS1 GO:0008152| metabolic process SMPD1;NEU2;ACAT1 GO:0006687| glycosphingolipid metabolic process NEU2;SMPD1 GO:0016042| lipid catabolic process PLA2G1B;DAGLA;NEU2;NAPEPLD 18103:[DB14011 DB02266] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes PPARG;PTGS1;PTGS2 common pathways GO:0006355| regulation of transcription, DNA-dependent AR;PPARA;PPARG GO:0042493| response to drug PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0006631| fatty acid metabolic process PTGS1;PPARA;PTGS2;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARA;PPARG GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0030224| monocyte differentiation PPARG GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;AKR1C3;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;PPARA GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0071455| cellular response to hyperoxia PPARG GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0010042| response to manganese ion PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR;PPARA GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;AKR1C3 GO:0009750| response to fructose stimulus PTGS2 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0032496| response to lipopolysaccharide CNR2;PTGS2;CYP1A2;OPRM1;CNR1;CYP1A1;IDO1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0042060| wound healing ALOX15;OPRM1;PPARA GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071284| cellular response to lead ion PTGS2 GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;AR;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation AKR1C3;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;AR GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0071300| cellular response to retinoic acid PPARG GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;AR;PPARG;TRPV4;TRPV1 GO:0045087| innate immune response PPARG GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0043312| neutrophil degranulation TTR;CAT;ALOX5 GO:0042594| response to starvation PPARG;ACAT1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport ABCC1;SLC22A6;CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0007283| spermatogenesis SOD1;CNR1;AR GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia PPARA;CAT;CHRNA7;CYP1A1 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0031000| response to caffeine PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:1902219| PTGS2 GO:0007186| G-protein coupled receptor signaling pathway AKR1C3;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;GPR18;PPARG GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0008202| steroid metabolic process CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP3A4;CYP3A7;CYP1A2;AKR1C3;HMGCR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0010468| regulation of gene expression AR;PPARA;CYP1A2 GO:0097756| PTGS2;HMGCR GO:0030282| bone mineralization PTGS2;ALOX15 GO:0006810| transport TTR;AR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0046697| decidualization PTGS2 GO:0007568| aging CAT;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0015909| long-chain fatty acid transport PPARG GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0042574| retinal metabolic process AKR1C3;CYP1B1 GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| GSR;PTGS2;GPX1;PTGS1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0019371| cyclooxygenase pathway PTGS2;AKR1C3;PTGS1 GO:0071379| cellular response to prostaglandin stimulus AKR1C3;PPARG GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0061614| PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death AKR1C3;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042448| progesterone metabolic process CYP17A1;AKR1C3 GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:1904706| PPARG GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0071277| cellular response to calcium ion ALOX15;AKR1C3 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0048469| cell maturation PPARG GO:0000060| protein import into nucleus, translocation AKR1C3;OPRD1 GO:0019233| sensory perception of pain OPRD1;PTGS2;CNR2;OPRM1;CNR1;HTR2A;TRPV1;TRPA1 GO:0006351| transcription, DNA-dependent PPARG;AR;PPARA GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARA;AR;PPARG GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;AKR1C3;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:1990776| PTGS2 GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARA;PPARG GO:0042572| retinol metabolic process AKR1C3;TTR;CYP1B1 GO:0042953| lipoprotein transport PPARG GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;PPARA;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0008283| cell proliferation HTR1A;AR;GPX1;CYP1A1 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0006919| activation of caspase activity PPARG GO:0007548| sex differentiation CYP17A1;AR GO:0032868| response to insulin stimulus AANAT;CAT;PPARA;TRPV4 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071276| cellular response to cadmium ion SOD1;AKR1C3;CYP1A2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001523| retinoid metabolic process TTR;NAPEPLD;AKR1C3 GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0007584| response to nutrient PPARG;AKR1C3;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0098656| VDAC1;SLC22A6 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;AR;PPARG;CYP1B1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:1905461| PPARG GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0019216| regulation of lipid metabolic process PPARA;CNR1;HMGCR;PPARG;CYP1A1 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;AR GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 18104:[DB14011 DB02377] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0051291| protein heterooligomerization GCH1;GLRA1;GLRB GO:0008217| regulation of blood pressure PPARG;GCH1;PTGS1;SOD1;PTGS2 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0006809| nitric oxide biosynthetic process GCH1;CYP1B1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006955| immune response CNR2;OPRD1;PNP GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0008152| metabolic process GCH1;ACAT1;SMPD1 GO:0045776| negative regulation of blood pressure GCH1;CNR1 GO:0034612| response to tumor necrosis factor GCH1;PTGS2 GO:0051260| protein homooligomerization GLRA1;GCH1;ACAT1;GLRA3 GO:0048265| response to pain TRPA1;TRPV1;GCH1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;PNP;TRPA1;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0050884| neuromuscular process controlling posture GCH1;GLRA1 GO:0042311| vasodilation GPX1;GCH1 GO:0043312| neutrophil degranulation PNP;ALOX5;CAT GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1;GCH1 18105:[DB14011 DB12305] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A3;ABCG2;TRPA1;CYP1A1;PPARG;SLC6A2;SMPD1;ABCC1;SLC6A4;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0048265| response to pain TRPV1;SLC6A2;TRPA1 GO:0035094| response to nicotine SLC6A3;CNR1;CHRNA7 GO:0007623| circadian rhythm AANAT;SLC6A4 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0007626| locomotory behavior OPRM1;SOD1;SLC6A3 GO:0051591| response to cAMP SLC6A3;AANAT GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;SLC6A3 GO:0055085| transmembrane transport ABCC1;SLC6A2;CACNA1G;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;SLC6A3;ABCG2;TRPV3;CACNA1H;TRPV2;SLC6A4 GO:0001666| response to hypoxia CHRNA7;CAT;SLC6A4;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;SLC6A4 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;SLC6A4;TRPA1;PPARG;CYP1A1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;SLC6A4;CAT GO:0007568| aging CYP1A1;SLC6A3;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT GO:0006810| transport TRPV1;CACNA1I;ABCG2;SLC6A2;ABCC1;TRPV2 GO:0051260| protein homooligomerization GLRA1;GLRA3;SLC6A4;ACAT1 GO:0007268| synaptic transmission OPRD1;OPRM1;GLRA3;HTR2A;SLC6A2;CACNA1G;GLRA1;GLRB;VDAC1 GO:0007595| lactation SLC6A3;SLC29A1 GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;SLC6A3 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC6A3;SLC6A4 GO:0042310| vasoconstriction SLC6A4;HTR1A GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;SLC6A3;PPARG;CYP1A1;TRPA1 GO:0009636| response to toxin CYP1B1;CYP1A1;SLC6A4;CAT;GPX1 GO:0042053| regulation of dopamine metabolic process HTR1A;SLC6A3 GO:0007584| response to nutrient PPARG;HMGCR;CNR1;SLC6A4 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7;SLC6A4 GO:0007420| brain development ACAT1;SLC6A4 18106:[DB14011 DB02463] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02463|2-(2-Hydroxy-Phenyl)-1h-Indole-5-Carboxamidine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18107:[DB14011 DB01619] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01619|Phenindamine HRH1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;HRH1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;HRH1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0008542| visual learning HRH1;HMGCR GO:0006954| inflammatory response PTGS2;CNR2;HRH1;ALOX5;PTGS1;TRPV1;ALOX15;IDO1 GO:0007613| memory CHRNA7;HRH1;PTGS2;CNR1;HTR2A GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;HRH1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A 18108:[DB14011 DB05892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05892|RI 624 NGF common genes common pathways GO:0043524| negative regulation of neuron apoptosis SOD1;NGF GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;NGF GO:0043065| positive regulation of apoptotic process SMPD1;NGF;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0006919| activation of caspase activity NGF;PPARG GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;NGF GO:0010628| positive regulation of gene expression TRPV4;NGF 18109:[DB14011 DB07425] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07425|Sobetirome THRB common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PPARG;THRB GO:0006351| transcription, DNA-dependent THRB;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;THRB GO:0008016| regulation of heart contraction CACNA1H;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;THRB;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;THRB;PLA2G1B GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;THRB GO:0006355| regulation of transcription, DNA-dependent PPARG;THRB GO:0007605| sensory perception of sound GPX1;SOD1;THRB GO:0045892| negative regulation of transcription, DNA-dependent THRB;PPARG 18110:[DB14011 DB02942] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 18111:[DB14011 DB11723] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11723|Dutogliptin DPP4 common genes common pathways GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 18112:[DB14011 DB04153] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0045777| positive regulation of blood pressure CNR1;ADH5 GO:0001523| retinoid metabolic process ADH5;NAPEPLD GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;ADH5;CYP1A1;CYP2C9;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0022900| electron transport chain GSR;IDO1;ADH5;CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;IDO1;ADH5 18113:[DB14011 DB04792] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04792|2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18114:[DB14011 DB02161] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02161|Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester CES1;CES1 common genes common pathways GO:0008152| metabolic process ACAT1;CES1;SMPD1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4;CES1 GO:0009636| response to toxin CES1;CAT;GPX1;CYP1A1;CYP1B1 GO:0006695| cholesterol biosynthetic process CES1;HMGCR GO:0030855| epithelial cell differentiation CES1;VDAC1;PPARG 18115:[DB14011 DB05004] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05004|Peptide YY (3-36) NPY2R;NPY1R;NPY5R;NPY4R common genes common pathways GO:0042755| eating behavior OPRM1;OPRD1;NPY5R GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;NPY2R GO:0032229| negative regulation of synaptic transmission, GABAergic CNR2;NPY5R GO:0045987| positive regulation of smooth muscle contraction NPY2R;PTGS2 GO:0008217| regulation of blood pressure NPY1R;PPARG;PTGS1;PTGS2;SOD1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;NPY2R GO:0001662| behavioral fear response NPY2R;VDAC1;HTR1A GO:0040014| regulation of multicellular organism growth SOD1;NPY1R GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway NPY1R;NPY2R;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration NPY2R;TRPV4;TRPV1;HTR2A;OPRM1 GO:0010811| positive regulation of cell-substrate adhesion NPY2R;ALOX15 GO:0065009| regulation of molecular function TRPV1;NPY2R GO:0007165| signal transduction CACNA1I;NPY1R;NPY2R;PLA2G1B;NPY4R;SMPD1;PPARG;GPR18;NPY5R;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0007268| synaptic transmission GLRA1;CACNA1G;VDAC1;NPY1R;NPY2R;GLRB;NPY4R;HTR2A;GLRA3;OPRM1;OPRD1;NPY5R GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1;TRPA1;NPY1R;TRPV1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;NPY5R;CHRNA7 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger NPY1R;CNR1;CNR2;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;NPY4R;NPY1R;NPY2R;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;NPY5R GO:0007568| aging NPY5R;CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;NPY2R;CYP1A1 GO:0048661| positive regulation of smooth muscle cell proliferation NPY5R;PTGS2;HMGCR GO:0051967| negative regulation of synaptic transmission, glutamatergic NPY2R;HTR2A GO:0043066| negative regulation of apoptotic process GPX1;NPY5R;CAT;PTGS2;HMGCR;SOD1 GO:0007626| locomotory behavior SOD1;OPRM1;NPY1R;NPY2R GO:0007218| neuropeptide signaling pathway GLRA1;NPY1R;GLRB;NPY2R;NPY4R;GLRA3;OPRM1;OPRD1;NPY5R GO:0008284| positive regulation of cell proliferation NPY5R;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A 18116:[DB14011 DB05740] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes CHRNA7 common pathways GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1;CHRNA4 GO:1901214| CHRNA7 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;HTR2A;GPR12 GO:0042391| regulation of membrane potential CHRNA4;CACNA1H;GLRB;CACNA1G;CHRNB2;GLRA1 GO:0007605| sensory perception of sound SOD1;GPX1;CHRNA9;CHRNB2 GO:0045759| negative regulation of action potential CNR1;CNR2;CHRNB2 GO:0098815| CHRNA7 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CHRNA4;CHRNA7;CAT;CHRNB2;CYP1A1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:1902991| CHRNA7 GO:0014059| regulation of dopamine secretion CHRNB2;CHRNA4;HTR2A GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;CHRNA4 GO:0095500| CHRNA4;CHRNA7;CHRNB2 GO:0034220| ion transmembrane transport GLRA3;CHRNA2;CHRNA4;CHRNA7;CHRNB2;TRPA1;GLRA1;CHRNA9;CHRNA10;GLRB;TRPV1 GO:1905920| CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0042220| response to cocaine CHRNB2;SMPD1;OPRM1;CNR1 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0007626| locomotory behavior CHRNB2;SOD1;OPRM1;CHRNA4 GO:0007612| learning CHRNB2;VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CHRNA10 GO:0001508| regulation of action potential GLRA1;CACNA1G;CHRNB2;CHRNA4 GO:0007611| learning or memory CNR1;CHRNA7 GO:1905144| CHRNA7;CHRNB2 GO:0007614| short-term memory CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA4;SLC29A1;CHRNA2;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;CHRNA10;CHRNB2;CHRNA9;GLRA1 GO:1905906| CHRNA7 GO:0050893| sensory processing CHRNA7 GO:0035640| exploration behavior HTR1A;CHRNA4 GO:0035094| response to nicotine CHRNB2;CNR1;CHRNA7;CHRNA2;CHRNA4 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0050808| synapse organization CHRNA7 GO:0006939| smooth muscle contraction CHRNB2;HTR2A GO:0070588| calcium ion transmembrane transport TRPA1;CHRNA9;CACNA1G;TRPM8;CHRNA10;TRPV4;CACNA1I;TRPV1;TRPV3;OPRM1;CACNA1H;CHRNA7;TRPV2 GO:1900273| CHRNA7 GO:1904645| CHRNA7 GO:0007165| signal transduction SMPD1;CHRNB2;GPR18;CHRNA9;PPARG;CHRNA10;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA2;CHRNA4;CHRNA7 GO:0050890| cognition CHRNA4;CHRNA7;CHRNB2 GO:0097061| dendritic spine organization CHRNA7 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7;CHRNB2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;CHRNA10;CHRNA9 GO:0007601| visual perception CHRNB2;GLRA1;CRYZ;GLRB;CYP1B1 GO:0042053| regulation of dopamine metabolic process HTR1A;CHRNB2 GO:0051291| protein heterooligomerization CHRNA2;GLRB;CHRNB2;GLRA1 GO:0006812| cation transport TRPM8;CHRNA9 GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;CHRNA2;CHRNA4;TRPV2;GLRA1;TRPA1;CHRNA9;CACNA1G;CHRNB2;TRPM8;CHRNA10;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CHRNA2;CHRNA9;CHRNB2;CHRNA10 GO:0045471| response to ethanol CAT;OPRM1;HMGCR;CNR1;SOD1;CHRNB2 GO:0019233| sensory perception of pain CHRNA4;HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1;TRPV1;TRPA1;CHRNB2 GO:1902430| CHRNA7 GO:0006816| calcium ion transport TRPM8;TRPV4;CACNA1I;TRPV1;CHRNA10;CHRNA9;TRPA1;CACNA1G;CHRNB2;CHRNA7;CHRNA4;TRPV2;CACNA1H;TRPV3 GO:0008542| visual learning HMGCR;CHRNB2 GO:0007268| synaptic transmission OPRM1;OPRD1;HTR2A;GLRA3;CHRNA4;CACNA1G;GLRA1;VDAC1;GLRB GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902004| CHRNA7 18117:[DB14011 DB00399] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 common genes ABCC1 common pathways GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;PTGS1;NAAA;GPX1;FDPS;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 GO:0016032| viral reproduction HTR2A;FDPS;VDAC1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;FDPS;CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC1;ABCG2;CACNA1I;TRPV1;TRPV2 GO:0008299| isoprenoid biosynthetic process HMGCR;FDPS;GGPS1 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0045540| regulation of cholesterol biosynthetic process GGPS1;HMGCR;FDPS GO:0008203| cholesterol metabolic process CAT;FDPS;HMGCR GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;FDPS GO:0060326| cell chemotaxis ABCC1 GO:0099133| ABCC1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0006691| leukotriene metabolic process ALOX5;ALOX15;ABCC1 18118:[DB14011 DB06362] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG;TOP2A GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;PLA2G1B GO:0048511| rhythmic process AANAT;TOP2A;PPARG 18119:[DB14011 DB04768] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 18120:[DB14011 DB03052] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1;TBXAS1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B;TBXAS1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1;TBXAS1 GO:0006693| prostaglandin metabolic process TBXAS1;PTGS2;PTGS1 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;TBXAS1;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1 GO:0006631| fatty acid metabolic process ALOX15;TBXAS1;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;TBXAS1;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1 18121:[DB14011 DB02472] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02472|6-Hydroxy-7,8-Dihydro Purine Nucleoside ADA common genes common pathways GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0001890| placenta development SOD1;ADA;PPARG GO:0001889| liver development CYP1A1;ADA;ACAT1 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;ADA;GPX1 GO:0001666| response to hypoxia CYP1A1;ADA;CAT;CHRNA7 GO:0007568| aging CYP1A1;ADA;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;CAT;ADA;SOD1;HTR2A;CYP1A2;PTGS2 GO:0043278| response to morphine ADA;CNR1;OPRM1 GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0030324| lung development CYP1A2;ADA GO:0033197| response to vitamin E ADA;CAT GO:0007155| cell adhesion CYP1B1;ADA GO:0043066| negative regulation of apoptotic process ADA;GPX1;CAT;HMGCR;PTGS2;SOD1 18122:[DB14011 DB00437] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00437|Allopurinol XDH;AOX1;XDH;SLC22A8;SLC22A7 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;XDH GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0007595| lactation XDH;SLC29A1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0006919| activation of caspase activity XDH;PPARG GO:0006811| ion transport CACNA1H;TRPV3;SLC22A8;GLRA3;TRPV2;SLC22A7;CHRNA7;CACNA1G;GLRA1;TRPA1;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8 GO:0098656| SLC22A8;SLC22A7;VDAC1 GO:0022900| electron transport chain CYP1A2;XDH;IDO1;GSR;AOX1 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;XDH;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP2C9;CYP1A1;AOX1;CRYZ GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;AOX1;CYP3A4;CYP1A2 GO:0055085| transmembrane transport SLC22A8;CACNA1H;TRPV3;SLC22A7;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1 18123:[DB14011 DB05241] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05241|XL765 PIK3CA;PIK3CG;PIK3CD;PIK3CB;MTOR common genes common pathways GO:0040014| regulation of multicellular organism growth PIK3CA;SOD1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;PIK3CG;TRPV4;TRPV1 GO:0014065| phosphatidylinositol 3-kinase cascade PIK3CB;HTR2A;PIK3CA;PIK3CG;PIK3CD GO:0060055| angiogenesis involved in wound healing GPX1;PIK3CB GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;PIK3CB;CNR1;GPR12;PLA2G1B;CACNA1I;PIK3CD;SMPD1;MTOR;PPARG;GPR18 GO:0033138| positive regulation of peptidyl-serine phosphorylation PIK3CA;PTGS2;OPRD1 GO:0007420| brain development MTOR;ACAT1 GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4;MTOR GO:0060612| adipose tissue development ACAT1;PIK3CA GO:0009791| post-embryonic development MTOR;CYP1A2 GO:0007584| response to nutrient HMGCR;CNR1;MTOR;PPARG GO:0001889| liver development ACAT1;PIK3CA;CYP1A1 GO:0001525| angiogenesis PIK3CA;PTGS2;CYP1B1;PIK3CG GO:0045859| regulation of protein kinase activity SOD1;MTOR GO:0071320| cellular response to cAMP PIK3CG;AANAT GO:0043524| negative regulation of neuron apoptosis PIK3CA;SOD1 GO:0001934| positive regulation of protein phosphorylation MTOR;CHRNA7 GO:0043087| regulation of GTPase activity MTOR;SOD1 GO:0010976| positive regulation of neuron projection development CNR1;MTOR GO:0006954| inflammatory response PIK3CG;PIK3CD;ALOX15;IDO1;TRPV1;PIK3CB;CNR2;PTGS2;PIK3CA;ALOX5;PTGS1 GO:0010942| positive regulation of cell death MTOR;PTGS2 GO:0030217| T cell differentiation PIK3CD;GPR18 GO:0008542| visual learning HMGCR;MTOR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;HTR2A GO:0009611| response to wounding CYP1A1;GPX1;PIK3CB GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;PIK3CB;CNR2;OPRM1;OPRD1;PIK3CA;PIK3CG;PPARG;GPR18 GO:0071456| cellular response to hypoxia MTOR;PTGS2;OPRD1;SLC29A1 GO:0010468| regulation of gene expression PIK3CA;CYP1A2 GO:0006874| cellular calcium ion homeostasis CHRNA7;PIK3CB;HTR2A;GPR12;TRPV4;TRPM8 GO:0045429| positive regulation of nitric oxide biosynthetic process MTOR;TRPV1;PTGS2;OPRM1 GO:0002376| immune system process IDO1;PIK3CD;PIK3CG GO:0043085| positive regulation of catalytic activity SOD1;PIK3CG GO:0043200| response to amino acid stimulus GLRA3;MTOR;GLRB GO:0000187| activation of MAPK activity PIK3CB;SOD1;CHRNA7;PLA2G1B GO:0042220| response to cocaine CNR1;OPRM1;MTOR;SMPD1 GO:0050769| positive regulation of neurogenesis MTOR;OPRM1 GO:0010628| positive regulation of gene expression TRPV4;MTOR;PIK3CD;PIK3CB GO:0043406| positive regulation of MAP kinase activity PIK3CG;HTR2A GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;MTOR GO:0060135| maternal process involved in female pregnancy MTOR;CNR1 GO:0030838| positive regulation of actin filament polymerization ALOX15;MTOR GO:0042060| wound healing MTOR;ALOX15;OPRM1 GO:0043542| endothelial cell migration CYP1B1;PIK3CA GO:0071333| cellular response to glucose stimulus SLC29A1;PIK3CA GO:0071230| cellular response to amino acid stimulus MTOR;GLRA1 GO:0007155| cell adhesion CYP1B1;PIK3CB GO:0045087| innate immune response PIK3CD;PPARG;PIK3CG;PIK3CA;PIK3CB GO:0030593| neutrophil chemotaxis PIK3CG;PIK3CD;PLA2G1B GO:0007569| cell aging SOD1;MTOR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;MTOR GO:0043278| response to morphine MTOR;OPRM1;CNR1 GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CG;PIK3CD;MTOR;PIK3CA;GPX1;PIK3CB GO:0060326| cell chemotaxis PIK3CB;PIK3CA;ABCC1 18124:[DB14011 DB01024] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01024|Mycophenolic acid IMPDH1;IMPDH2;UGT1A1;UGT1A9;UGT2B7;UGT1A7;UGT1A6 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;UGT1A1;CYP1A1;IDO1 GO:0007623| circadian rhythm AANAT;IMPDH2 GO:0043312| neutrophil degranulation IMPDH1;IMPDH2;CAT;ALOX5 GO:0042594| response to starvation PPARG;UGT1A1;ACAT1 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;IMPDH1;CRYZ;ALOX5;PTGS1;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;IMPDH2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;UGT1A1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0006631| fatty acid metabolic process UGT1A7;PTGS2;PTGS1;ALOX15 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6;UGT1A7 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP3A4;UGT2B7 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;UGT1A9;UGT1A1;UGT1A7;CYP3A4;UGT1A6;CYP1A2 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;UGT1A1 GO:0001889| liver development ACAT1;UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;UGT2B7;NAAA;PTGS1;GPX1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0008152| metabolic process ACAT1;UGT2B7;UGT1A7;UGT1A6;SMPD1;UGT1A9;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C9;UGT1A9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;UGT1A6;CYP3A7;PTGS1 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0051289| protein homotetramerization IMPDH2;CAT;CRYZ;TRPA1;TRPM8;TRPV1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;UGT1A9 GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;UGT1A1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0007584| response to nutrient PPARG;UGT1A1;CNR1;HMGCR 18125:[DB14011 DB00473] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways GO:0086016| SCN5A;CACNA1G;SCN10A GO:0086015| CACNA1G;SCN5A GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;ABCC1;CACNA1G;SCN10A;SCN5A;TRPV2;TRPV3;CACNA1H GO:0086002| SCN5A;CACNA1G GO:0086091| SCN5A;CACNA1G GO:0071277| cellular response to calcium ion ALOX15;SCN5A GO:0019233| sensory perception of pain TRPA1;SCN10A;TRPV1;CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1 GO:0035725| sodium ion transmembrane transport CACNA1I;SCN10A;CACNA1G;SCN5A;CACNA1H GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;SCN10A;SCN5A;CACNA1H GO:0002027| regulation of heart rate SCN5A;CACNA1G;SCN10A GO:0007600| sensory perception SCN10A;OPRM1;TRPV2 GO:0086010| CACNA1G;SCN10A;CACNA1I;CACNA1H;SCN5A GO:0034765| regulation of ion transmembrane transport SCN5A;CACNA1H;CACNA1I;CACNA1G;SCN10A GO:0086045| CACNA1G;SCN5A GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;SCN5A;SCN10A;CACNA1G;GLRA1;TRPA1;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN5A;SCN10A;CACNA1G GO:0086046| CACNA1G;SCN5A 18126:[DB14011 DB00441] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes SLC29A1 common pathways GO:0007595| lactation SLC29A1 GO:0051289| protein homotetramerization CDA;CAT;TRPA1;CRYZ;TRPM8;TRPV1 GO:0015858| nucleoside transport SLC29A1;SLC29A2;SLC28A1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CDA GO:0045471| response to ethanol CAT;CNR1;SOD1;OPRM1;HMGCR;TYMS GO:0030431| sleep SLC29A1;HTR2A;CACNA1I GO:0015862| uridine transport SLC29A1 GO:0008152| metabolic process ACAT1;RRM1;SMPD1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0015949| nucleobase-containing small molecule interconversion CMPK1;RRM1;GSR;TYMS GO:0006139| nucleobase-containing compound metabolic process SLC28A1;SLC29A1;SLC29A2;CMPK1;DCK GO:0008283| cell proliferation CYP1A1;GPX1;SLC29A2;HTR1A GO:0009636| response to toxin CYP1B1;TYMS;CYP1A1;GPX1;CAT GO:0014070| response to organic cyclic compound TRPA1;TYMS;CYP1A1;PPARG;ACAT1;AANAT;PTGS2;CYP1A2 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;RRM1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0042493| response to drug ABCB1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TYMS;TRPA1;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0099133| ABCC1;ABCC10 GO:0033189| response to vitamin A CAT;TYMS;CYP1A1;PPARG GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;GLRA1 GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0007623| circadian rhythm TYMS;AANAT GO:0030308| negative regulation of cell growth PPARG;CDA GO:0034097| response to cytokine stimulus TYMS;PTGS2;AANAT GO:0043312| neutrophil degranulation CDA;CAT;ALOX5 GO:0032259| methylation CYP1A2;TYMS GO:0055085| transmembrane transport ABCC10;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV4;ABCB1;CACNA1I;VDAC1;TRPV1 GO:1901642| SLC29A2;SLC28A3;SLC29A1;SLC28A1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CYP1A1;TYMS GO:0006810| transport ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1;TRPV2 18127:[DB14011 DB02467] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways 18128:[DB14011 DB01664] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01664|(S)-Des-Me-Ampa GRIA2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;GRIA2;SLC29A1;GLRA1;GLRB;TRPV1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GRIA2;TRPA1;GLRA1;TRPV1;GLRB GO:0007268| synaptic transmission GLRA1;CACNA1G;VDAC1;GLRB;GLRA3;HTR2A;OPRM1;OPRD1;GRIA2 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;GRIA2;CHRNA7 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;GRIA2;CHRNA7 18129:[DB14011 DB01046] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways GO:1902476| GLRA1;GLRB;CLCN2;GLRA3 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1;CBR1 GO:0006811| ion transport GLRA3;CLCN2;TRPV3;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I GO:0006821| chloride transport GLRA1;GLRB;CLCN2;GLRA3 GO:0034765| regulation of ion transmembrane transport CACNA1H;CLCN2;CACNA1I;CACNA1G GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;CBR1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1A1;CYP2C9;CRYZ GO:0030855| epithelial cell differentiation CBR1;VDAC1;PPARG GO:0055085| transmembrane transport TRPV2;CLCN2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;ABCC1;CACNA1G GO:0034220| ion transmembrane transport CHRNA7;GLRA3;CLCN2;TRPV1;GLRB;GLRA1;TRPA1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4;CBR1 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;TRPV2;CLCN2 18130:[DB14011 DB08103] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways GO:0043312| neutrophil degranulation TTR;CAT;ALOX5 GO:0006810| transport TTR;TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0001523| retinoid metabolic process NAPEPLD;TTR 18131:[DB14011 DB03147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes GSR common pathways GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;ACAD8;ACADS;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;CYB5R3;CYB5R1;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;ACADM;FDXR;PPARG;CYP2C9;ACOX1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1;ACOX1 GO:0042136| neurotransmitter biosynthetic process DAGLA;NOS1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;CYB5R3;PTGS1;NQO2;CYP2C9;NQO1;POR;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0008152| metabolic process ACAD8;ACAT1;ACADS;GCDH;SMPD1;IVD;ACADM;ACOX1 GO:0016125| sterol metabolic process FDXR;CYP17A1;CYP1B1 GO:0016126| sterol biosynthetic process CYB5R1;CYB5R3;HMGCR GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;AIFM1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042307| positive regulation of protein import into nucleus PTGS2;TPR GO:0001889| liver development CYP1A1;GFER;ACAT1 GO:0070988| demethylation CYP1A1;POR GO:0006351| transcription, DNA-dependent PPARG;ACAD8 GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;MAOB;NQO1 GO:0045776| negative regulation of blood pressure NOS1;CNR1 GO:0019430| removal of superoxide radicals SOD1;NQO1 GO:0007595| lactation XDH;SLC29A1 GO:0016032| viral reproduction VDAC1;HTR2A;TPR GO:0009408| response to heat NOS1;TRPV1;TRPV3;SOD1;TRPV2 GO:0010942| positive regulation of cell death PTGS2;AIFM1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;POR GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0010629| negative regulation of gene expression OPRD1;XDH GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;NOS1;CYP2C19 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0007165| signal transduction OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;TXNRD1;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0007520| myoblast fusion NOS1;CACNA1H GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;TXNRD1;ACADM;ACOX1;CYP1A1;PPARG GO:0045454| cell redox homeostasis DLD;TXNRD1;GPX1;ERO1B;GSR;NOS1 GO:0007584| response to nutrient CNR1;HMGCR;NQO1;PPARG;POR GO:0070301| cellular response to hydrogen peroxide CYP1B1;NQO1;AIFM1 GO:0055088| lipid homeostasis PPARG;ACOX1 GO:0019395| fatty acid oxidation POR;GCDH;PPARG;ACOX1 GO:0006749| glutathione metabolic process SOD1;GPX1;GSR GO:0006809| nitric oxide biosynthetic process NOS1;NQO1;CYP1B1 GO:0033555| multicellular organismal response to stress NOS1;IDO1 GO:0015949| nucleobase-containing small molecule interconversion TXNRD1;GSR GO:0006919| activation of caspase activity PPARG;AIFM1;XDH GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;PPARG;CYP1A1;NQO1 GO:0010269| response to selenium ion GPX1;MAOB GO:0009636| response to toxin CYP1B1;MAOB;NQO1;CYP1A1;GPX1;AIFM1;CAT GO:0043267| negative regulation of potassium ion transport HTR2A;NOS1 GO:0008283| cell proliferation TXNRD1;GPX1;HTR1A;CYP1A1 GO:0043312| neutrophil degranulation CYB5R3;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;TRPV1;TRPV4;PPARG GO:0042311| vasodilation GPX1;NOS1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;POR;NQO1 GO:0002576| platelet degranulation SOD1;CYB5R1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;PPARG;PLA2G1B GO:0006695| cholesterol biosynthetic process CYB5R3;HMGCR GO:0006635| fatty acid beta-oxidation ACAT1;ACADS;ACOX1;ACADM GO:0009812| flavonoid metabolic process CYP1A1;POR GO:0034599| cellular response to oxidative stress TXNRD1;GPX1;CAT;SOD1;GSR GO:0008203| cholesterol metabolic process CAT;HMGCR;CYB5R3;FDXR GO:0007623| circadian rhythm NDUFA9;AANAT GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;IDO1;CYP1A1;MAOB GO:0009083| branched chain family amino acid catabolic process IVD;DLD;ACAT1;ACAD8 GO:0006694| steroid biosynthetic process CYB5R1;CYP17A1;FDXR;HMGCR;CYB5R3 GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0055114| oxidation-reduction process CYP1A2;MAOA;CYP3A7;PTGS2;XDH;HMGCR;CYP3A4;SOD1;CYB5R3;DPYD;PTGS1;ALOX5;GPX1;ACAD8;TXNRD1;AIFM1;DLD;ACADS;CAT;MAOB;ACADM;NQO2;FDXR;IVD;IL4I1;ACOX1;NQO1;NOS1;CYP2C9;CYP1A1;CRYZ;POR;CYP1B1;CYB5R1;GCDH;DAO;CYP17A1;GFER;CYP3A5;ALOX15;CYP2C19;NDUFA9;IDO1;GSR;ERO1B;CYP2D6 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;PPARG GO:0022900| electron transport chain NQO2;MAOB;GSR;IDO1;POR;XDH;CYP1A2;TXNRD1 GO:0006631| fatty acid metabolic process ACOX1;ACADM;ALOX15;PTGS2;ACADS;PTGS1 GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;MAOB;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;POR;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ACAD8 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;NQO1 GO:0098869| PTGS2;CAT;TXNRD1;PTGS1;GPX1;GSR GO:0042391| regulation of membrane potential DLD;CACNA1H;GLRB;CACNA1G;GLRA1 GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4;ERO1B GO:0007568| aging PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT;DLD;NQO1;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYB5R3;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;FDXR;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYB5R1 GO:0034605| cellular response to heat TPR;PTGS2;TRPV4;TRPV1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;NQO1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;NOS1 GO:0001666| response to hypoxia NOS1;CYP1A1;CHRNA7;CAT GO:0007283| spermatogenesis CNR1;SOD1;ACOX1 GO:0006915| apoptotic process VDAC1;AIFM1;GPX1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 18132:[DB14011 DB00235] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00235|Milrinone PDE3A common genes common pathways GO:0043117| positive regulation of vascular permeability PDE3A;TRPV4 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;PDE3A;CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0006629| lipid metabolic process PDE3A;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1 GO:0051591| response to cAMP AANAT;PDE3A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG;PDE3A GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;PDE3A GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;PDE3A 18133:[DB14011 DB03485] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03485|Alpha-D-Fucose LTF common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;LTF GO:0050830| defense response to Gram-positive bacterium LTF;PLA2G1B GO:0019731| antibacterial humoral response PLA2G1B;LTF GO:0043066| negative regulation of apoptotic process CAT;LTF;GPX1;SOD1;PTGS2;HMGCR GO:0045087| innate immune response PPARG;LTF GO:0043312| neutrophil degranulation ALOX5;LTF;CAT GO:0002376| immune system process LTF;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;LTF;PLA2G1B GO:0001503| ossification LTF;ALOX15 GO:0006351| transcription, DNA-dependent PPARG;LTF GO:0061844| PLA2G1B;LTF GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;GLRA3;CACNA1H;TRPV3;CHRNA7;LTF;TRPV2 GO:0002227| innate immune response in mucosa LTF;PLA2G1B GO:0001895| retina homeostasis LTF;SOD1 18134:[DB14011 DB03710] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03710|N5-(1-Imino-3-Butenyl)-L-Ornithine NOS1 common genes common pathways GO:0006809| nitric oxide biosynthetic process NOS1;CYP1B1 GO:0033555| multicellular organismal response to stress IDO1;NOS1 GO:0043267| negative regulation of potassium ion transport NOS1;HTR2A GO:0007520| myoblast fusion CACNA1H;NOS1 GO:0045454| cell redox homeostasis NOS1;GSR;GPX1 GO:0009408| response to heat NOS1;TRPV1;SOD1;TRPV3;TRPV2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9;NOS1 GO:0042136| neurotransmitter biosynthetic process DAGLA;NOS1 GO:0045776| negative regulation of blood pressure CNR1;NOS1 GO:0001666| response to hypoxia NOS1;CYP1A1;CAT;CHRNA7 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;NOS1;TRPV1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;NOS1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;PPARG GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;PPARG;PLA2G1B GO:0042311| vasodilation GPX1;NOS1 18135:[DB14011 DB14562] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14562|Andexanet alfa TFPI common genes common pathways GO:0032496| response to lipopolysaccharide IDO1;TFPI;CYP1A1;CNR1;OPRM1;CYP1A2;PTGS2;CNR2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;TFPI 18136:[DB14011 DB08824] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08824|Ioflupane I-123 SLC6A3 common genes common pathways GO:0007568| aging CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;SLC6A3 GO:0051591| response to cAMP AANAT;SLC6A3 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;SLC6A3;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;CACNA1H;TRPV3;TRPV2 GO:0042220| response to cocaine OPRM1;CNR1;SLC6A3;SMPD1 GO:0007626| locomotory behavior OPRM1;SOD1;SLC6A3 GO:0035094| response to nicotine CHRNA7;CNR1;SLC6A3 GO:0042493| response to drug SLC6A3;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0042053| regulation of dopamine metabolic process SLC6A3;HTR1A GO:0014070| response to organic cyclic compound SLC6A3;TRPA1;CYP1A1;PPARG;AANAT;ACAT1;PTGS2;CYP1A2 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC6A3 GO:0045471| response to ethanol SLC6A3;CAT;OPRM1;HMGCR;SOD1;CNR1 GO:0007595| lactation SLC6A3;SLC29A1 18137:[DB14011 DB05252] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ;NOS2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;IDO1;CYP1A1;NOS2 GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NOS2 GO:0001666| response to hypoxia NOS2;CYP1A1;CHRNA7;CAT 18138:[DB14011 DB07168] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways GO:0007399| nervous system development SMPD1;GLRB;CAMK2B GO:0035556| intracellular signal transduction CAMK2B;PLA2G1B GO:0051924| regulation of calcium ion transport OPRD1;CAMK2B GO:0010976| positive regulation of neuron projection development CAMK2B;CNR1 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CAMK2B;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0065009| regulation of molecular function CAMK2B;TRPV1 18139:[DB14011 DB07276] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07276|5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;MAPK8IP1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7 GO:0009411| response to UV CAT;MAPK8 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;MAPK8 GO:0071260| cellular response to mechanical stimulus PTGS2;MAPK8 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;MAPK8;CNR1;SOD1;PTGS2 GO:0042752| regulation of circadian rhythm MAPK8;PPARG GO:0048511| rhythmic process PPARG;AANAT;MAPK8 GO:0010628| positive regulation of gene expression MAPK8;TRPV4 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;MAPK8;CAT;MAPK8IP1 GO:0006355| regulation of transcription, DNA-dependent MAPK8IP1;PPARG GO:0051247| positive regulation of protein metabolic process MAPK8;CHRNA7 18140:[DB14011 DB01927] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01927|Duroquinone NQO1 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;NQO1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP2C9;CYP1A1;NQO1;CRYZ GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0007568| aging CYP1A1;NQO1;CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;NQO1 GO:0006979| response to oxidative stress NQO1;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;NQO1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;NQO1;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0019430| removal of superoxide radicals NQO1;SOD1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NQO1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;TRPA1;NQO1;CYP1A1;PPARG GO:0009636| response to toxin NQO1;CYP1A1;CYP1B1;CAT;GPX1 GO:0007584| response to nutrient HMGCR;CNR1;NQO1;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1;NQO1 18141:[DB14011 DB08995] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08995|Diosmin AHR common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent AHR;PPARG GO:0048511| rhythmic process AANAT;AHR;PPARG GO:0006915| apoptotic process GPX1;VDAC1;AHR GO:0010468| regulation of gene expression CYP1A2;AHR GO:0045893| positive regulation of transcription, DNA-dependent AHR;PPARG GO:0006355| regulation of transcription, DNA-dependent AHR;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AHR GO:0009410| response to xenobiotic stimulus AHR;GPX1 GO:0009636| response to toxin CYP1B1;CYP1A1;AHR;CAT;GPX1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;AHR;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0006351| transcription, DNA-dependent PPARG;AHR GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG 18142:[DB14011 DB01390] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways GO:0007399| nervous system development SLC4A10;GLRB;SMPD1 GO:0035725| sodium ion transmembrane transport SLC4A10;SLC4A4;CACNA1H;CACNA1I;SLC4A8;CACNA1G;SLC4A7;SLC4A5 GO:0006821| chloride transport GLRA1;GLRB;GLRA3;SLC4A10 GO:0098656| SLC4A7;SLC4A5;VDAC1;SLC4A8;SLC4A4;SLC4A10 GO:0009791| post-embryonic development SLC4A10;CYP1A2 GO:0006811| ion transport TRPV3;SLC4A4;CACNA1H;GLRA3;SLC4A10;TRPV2;CHRNA7;CACNA1G;SLC4A7;TRPA1;GLRA1;SLC4A5;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;SLC4A8 GO:0006820| anion transport SLC4A4;SLC4A10;SLC4A5;GLRA1;SLC4A7;SLC4A8;VDAC1 GO:0010468| regulation of gene expression CYP1A2;SLC4A5 GO:0006810| transport SLC4A4;TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0009416| response to light stimulus AANAT;SLC4A10 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;SLC4A4;TRPM8;ABCG2;SLC4A8;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;ABCC1;SLC4A7;CACNA1G 18143:[DB14011 DB01851] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01851|Tetrabutylammonium Ion IGKC common genes common pathways GO:0001895| retina homeostasis IGKC;SOD1 GO:0006955| immune response IGKC;CNR2;OPRD1 GO:0002376| immune system process IDO1;IGKC GO:0045087| innate immune response IGKC;PPARG 18144:[DB14011 DB02545] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02545|Fexaramine NR1H4 common genes common pathways GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;NR1H4;CAT GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;NR1H4;OPRD1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;NR1H4;ALOX15;IDO1;TRPV1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1H4 GO:0006351| transcription, DNA-dependent NR1H4;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NR1H4 GO:0007043| cell-cell junction assembly TRPV4;NR1H4 GO:0032720| negative regulation of tumor necrosis factor production GPR18;NR1H4;CHRNA7 GO:0002376| immune system process NR1H4;IDO1 GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1;NR1H4 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1H4 GO:0050728| negative regulation of inflammatory response NR1H4;CNR2 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1H4 GO:0045087| innate immune response NR1H4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;NR1H4 18145:[DB14011 DB03619] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0046718| entry of virus into host cell HTR2A;SLC10A1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;NR1H4;OPRD1;CHRNA7;PPARG;GPBAR1;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0032088| negative regulation of NF-kappaB transcription factor activity NR1H4;CAT;CYP1B1 GO:0006811| ion transport GLRA3;TRPV3;SLCO1A2;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;SLC10A2;SLC10A1;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1;GSTP1 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0006749| glutathione metabolic process GSTP1;GSR;GPX1;SOD1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NR1H4 GO:0045471| response to ethanol GSTP1;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0006351| transcription, DNA-dependent NR1H4;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1H4 GO:0035725| sodium ion transmembrane transport CACNA1H;ABCB11;CACNA1G;CACNA1I GO:0008152| metabolic process SMPD1;GSTP1;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;GSTP1;CYP2C9 GO:0031667| response to nutrient levels GSTP1;SOD1 GO:0006954| inflammatory response ALOX5;PTGS1;NR1H4;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0016032| viral reproduction HTR2A;SLC10A1;VDAC1 GO:1904706| PPARG;GSTP1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;GPBAR1;PPARG GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;GSTP1 GO:0006810| transport ABCG2;TRPV1;CACNA1I;SLC10A2;SLC10A1;ABCC1;TRPV2;ABCB11 GO:0042593| glucose homeostasis NR1H4;CNR1;TRPV4;PPARG GO:0002376| immune system process NR1H4;IDO1 GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production GSTP1;GPR18;CHRNA7;NR1H4 GO:0098869| CAT;GPX1;PTGS1;PTGS2;GSR;GSTP1 GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0055085| transmembrane transport ABCB11;TRPV3;SLCO1A2;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;SLC10A1;SLC10A2;TRPV4;CACNA1I;VDAC1;TRPV1 GO:0007043| cell-cell junction assembly TRPV4;NR1H4 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0000302| response to reactive oxygen species GSTP1;CAT;GPX1;SOD1 GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;GSR;GSTP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR1H4 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;NR1H4;GSTP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;PPARG;TRPV4;TRPV1 GO:0045087| innate immune response PPARG;NR1H4 GO:0043312| neutrophil degranulation GSTP1;CAT;ALOX5 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1H4 GO:0050728| negative regulation of inflammatory response NR1H4;CNR2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1H4 18146:[DB14011 DB06374] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06374|Elacestrant ESR1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV4;TRPV1;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;ESR1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A;ESR1 18147:[DB14011 DB06082] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06082|PX-478 HIF1A common genes common pathways GO:0045766| positive regulation of angiogenesis CHRNA7;HIF1A;CYP1B1 GO:0010628| positive regulation of gene expression HIF1A;TRPV4 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;HIF1A GO:0046716| muscle cell homeostasis HIF1A;SOD1 GO:0010468| regulation of gene expression CYP1A2;HIF1A GO:0071456| cellular response to hypoxia PTGS2;OPRD1;HIF1A;SLC29A1 GO:0048514| blood vessel morphogenesis CYP1B1;HIF1A GO:0042593| glucose homeostasis TRPV4;PPARG;HIF1A;CNR1 GO:0006355| regulation of transcription, DNA-dependent HIF1A;PPARG GO:0045893| positive regulation of transcription, DNA-dependent HIF1A;PPARG GO:0061298| retina vasculature development in camera-type eye HIF1A;CYP1B1 GO:0042127| regulation of cell proliferation PTGS2;HIF1A;PTGS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HIF1A;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;HIF1A;GPX1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;HIF1A GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;HIF1A;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;HIF1A GO:0043524| negative regulation of neuron apoptosis HIF1A;SOD1 GO:0007595| lactation HIF1A;SLC29A1 GO:0008542| visual learning HIF1A;HMGCR GO:0006879| cellular iron ion homeostasis ABCG2;HIF1A;SOD1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2;HIF1A GO:0045821| positive regulation of glycolysis HIF1A;HTR2A GO:0001525| angiogenesis CYP1B1;HIF1A;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;HIF1A 18148:[DB14011 DB01723] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport CACNA1G;TRPA1;TRPV4;CACNA1I;TRPV1;FKBP1A;TRPM8;OPRM1;CACNA1H;TRPV3;TRPV2;CHRNA7 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;TRPV1;FKBP1A GO:0006936| muscle contraction CACNA1H;FKBP1A;GLRA1 GO:1902991| FKBP1A;CHRNA7 GO:0031000| response to caffeine FKBP1A;PPARG 18149:[DB14011 DB02727] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02727|N-Butyl-N'-Hydroxyguanidine NOS1 common genes common pathways GO:0007520| myoblast fusion NOS1;CACNA1H GO:0045454| cell redox homeostasis GSR;NOS1;GPX1 GO:0033555| multicellular organismal response to stress NOS1;IDO1 GO:0006809| nitric oxide biosynthetic process NOS1;CYP1B1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS1 GO:0045776| negative regulation of blood pressure NOS1;CNR1 GO:0042136| neurotransmitter biosynthetic process DAGLA;NOS1 GO:0042738| exogenous drug catabolic process CYP2C19;NOS1;CYP2C9;CYP1A2;CYP3A4 GO:0009408| response to heat TRPV1;NOS1;TRPV2;SOD1;TRPV3 GO:0071363| cellular response to growth factor stimulus TRPV1;NOS1;CAT;OPRD1 GO:0001666| response to hypoxia CAT;CHRNA7;NOS1;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NOS1;PPARG GO:0042311| vasodilation NOS1;GPX1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;NOS1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NOS1 18150:[DB14011 DB01439] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes OPRM1;OPRD1 common pathways GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1 GO:0044849| OPRK1;OPRM1 GO:0070588| calcium ion transmembrane transport TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1 GO:0050951| sensory perception of temperature stimulus TRPM8;OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0007165| signal transduction OPRK1;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0042755| eating behavior OPRM1;OPRD1;OPRK1 GO:0008344| adult locomotory behavior OPRD1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus AANAT;CAT;TRPV4;OPRK1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain TRPA1;OPRK1;TRPV1;HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2 GO:0045471| response to ethanol OPRK1;CAT;SOD1;CNR1;OPRM1;HMGCR GO:0000060| protein import into nucleus, translocation OPRD1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2;CAT GO:0048149| behavioral response to ethanol OPRM1 GO:0010629| negative regulation of gene expression OPRD1 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GLRA1;CACNA1G;OPRK1;VDAC1;GLRB GO:0006955| immune response OPRK1;CNR2;OPRD1 GO:0007600| sensory perception OPRK1;OPRM1;TRPV2 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18;OPRK1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0042220| response to cocaine OPRM1;CNR1;OPRK1;SMPD1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR2;CNR1 GO:0042060| wound healing ALOX15;OPRM1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0033554| cellular response to stress OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;HTR2A GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;GLRA1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRB;GLRA1;GLRA3;OPRD1;OPRM1 GO:0007626| locomotory behavior OPRM1;SOD1;OPRK1 GO:0032094| response to food OPRM1;CYP1A1 GO:0043278| response to morphine OPRK1;OPRM1;CNR1 GO:0097237| OPRD1 GO:0032100| positive regulation of appetite OPRM1 18151:[DB14011 DB11324] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11324|Nonivamide TRPV1 common genes TRPV1 common pathways GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0048265| response to pain TRPA1;TRPV1 GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPA1;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0002024| diet induced thermogenesis TRPV1;TRPV4 GO:0001660| fever generation TRPV1 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0071502| cellular response to temperature stimulus TRPV1 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;TRPV1;GLRB;GLRA1;TRPA1 GO:0055085| transmembrane transport TRPV1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;TRPA1 GO:0071468| cellular response to acidity TRPV1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;TRPV2 GO:0007635| chemosensory behavior TRPV1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ALOX5;PTGS1;PTGS2;CNR2 GO:0014047| glutamate secretion TRPV1 GO:0051289| protein homotetramerization TRPV1;TRPM8;TRPA1;CRYZ;CAT GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1 GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:0006816| calcium ion transport CACNA1H;TRPV3;TRPV2;CHRNA7;CACNA1G;TRPA1;CACNA1I;TRPV4;TRPV1;TRPM8 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0002790| peptide secretion TRPV1 GO:0009268| response to pH TRPV1 GO:0098703| TRPV1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0050955| thermoception TRPA1;TRPV1;TRPM8 GO:0071312| cellular response to alkaloid TRPV1 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1 GO:1990090| TRPV1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;NAAA;GPX1;PTGS1;PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B GO:0001774| microglial cell activation TRPV1 GO:0048266| behavioral response to pain TRPV1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1 GO:1901594| TRPV1 GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPV1;TRPA1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0070588| calcium ion transmembrane transport TRPV3;CACNA1H;OPRM1;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8 GO:0065009| regulation of molecular function TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;OPRM1 GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 18152:[DB14011 DB00072] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;ERBB2;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;EGFR GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;CYP19A1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP19A1;CYP2C9;CYP1A1;PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent PPARG;ERBB2 GO:0022900| electron transport chain IDO1;GSR;CYP19A1;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;EGFR GO:0045087| innate immune response C1QA;C1S;C1QC;FCGR1A;C1QB;C1R;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;FCGR3B;FCGR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation EGFR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;EGFR GO:0030324| lung development CYP1A2;EGFR GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0007623| circadian rhythm AANAT;EGFR GO:0042127| regulation of cell proliferation PTGS1;PTGS2;EGFR GO:0042060| wound healing ERBB2;OPRM1;ALOX15;EGFR GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A;ERBB2 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0010628| positive regulation of gene expression ERBB2;TRPV4 GO:0007202| activation of phospholipase C activity EGFR;GPR55;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;EGFR;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0002376| immune system process FCGR2A;FCGR1A;IDO1;C1QB;C1R;C1QA;C1QC;C1S GO:0006979| response to oxidative stress EGFR;PTGS2;SOD1;PTGS1;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;EGFR;TRPV1 GO:0033993| response to lipid PPARG;EGFR GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;EGFR GO:0071363| cellular response to growth factor stimulus OPRD1;ERBB2;CAT;TRPV1;EGFR GO:0006954| inflammatory response FCGR2B;IDO1;ALOX15;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0006955| immune response FCGR2B;FCGR3B;C1R;FCGR1A;C1QC;FCGR3A;OPRD1;FCGR2C;CNR2 GO:0016032| viral reproduction HTR2A;VDAC1;FCGR2B GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0001934| positive regulation of protein phosphorylation ERBB2;CHRNA7;EGFR GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0007507| heart development ERBB2;PPARG GO:0001503| ossification ALOX15;EGFR GO:0007399| nervous system development ERBB2;SMPD1;GLRB GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP19A1 GO:0007166| cell surface receptor linked signaling pathway EGFR;TRPV1;TRPA1;ERBB2 GO:0051592| response to calcium ion AANAT;EGFR GO:0001889| liver development CYP1A1;EGFR;ACAT1 GO:0006351| transcription, DNA-dependent PPARG;ERBB2 GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;PPARG;ERBB2 GO:0006970| response to osmotic stress TRPV4;EGFR GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;EGFR GO:0045740| positive regulation of DNA replication EGFR;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;EGFR GO:0008283| cell proliferation EGFR;CYP1A1;ERBB2;GPX1;HTR1A GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;EGFR;CYP1A1;PPARG;TRPA1 GO:0007165| signal transduction CACNA1I;PLA2G1B;EGFR;FCGR1A;SMPD1;FCGR2B;PPARG;GPR18;ERBB2;CHRNA7;CNR2;OPRM1;OPRD1;FCGR2C;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;EGFR GO:0014065| phosphatidylinositol 3-kinase cascade ERBB2;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;EGFR GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response EGFR;TRPV4 18153:[DB14011 DB07497] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;PC GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG;PTGS1;NAAA;GPX1;PC;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;PC 18154:[DB14011 DB05737] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05737|Varespladib methyl PLA2G2A;PLA2G10 common genes common pathways GO:0050482| arachidonic acid secretion PLA2G10;PLA2G1B;PLA2G2A GO:0050729| positive regulation of inflammatory response TRPV4;PLA2G2A GO:0036150| PLA2G1B;PLA2G2A;PLA2G10 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;PLA2G10;CYP1A2;PTGS2;HMGCR;PLA2G2A;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0036148| PLA2G1B;PLA2G2A;PLA2G10 GO:0036149| PLA2G1B;PLA2G2A;PLA2G10 GO:0036152| PLA2G2A;PLA2G1B;PLA2G10 GO:0006644| phospholipid metabolic process PLA2G2A;PLA2G1B;NAPEPLD;PLA2G10 GO:0016042| lipid catabolic process DAGLA;PLA2G2A;PLA2G1B;NAPEPLD;PLA2G10 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;PLA2G2A;ALOX15;TRPV4 GO:0006654| phosphatidic acid biosynthetic process PLA2G10;PLA2G1B;PLA2G2A GO:0036151| PLA2G1B;PLA2G2A;PLA2G10 GO:0019369| arachidonic acid metabolic process PLA2G10;FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0050830| defense response to Gram-positive bacterium PLA2G1B;PLA2G2A 18155:[DB14011 DB03379] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03379|2-Carboxyethylphosphonic Acid TPI1 common genes common pathways GO:0008152| metabolic process TPI1;ACAT1;SMPD1 18156:[DB14011 DB07707] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07707|(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;ESR1;HTR2A;OPRM1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;NCOA2;PPARG;CYP1A1 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;ESR1;HTR2A;GPR12;CNR1;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV1;TRPV4;NCOA2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NCOA2;PLA2G1B;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0048511| rhythmic process PPARG;NCOA2;AANAT 18157:[DB14011 DB13146] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;ABCC4;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;ABCB1;HTR2A;SOD1;PTGS2;CYP1A2;CAT;GRIN2A;ABCC4 GO:0050905| neuromuscular process GLRA1;GLRB;GRIN1 GO:0099133| ABCC4;ABCC1 GO:0043278| response to morphine CNR1;GRIN1;OPRM1 GO:0010243| response to organic nitrogen TRPV1;PTGS2;ABCC4 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;HMGCR;PTGS2 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIA2;SLC29A1;CHRNA7;GRIN2A;OPRM1;GRIA3;GRIN1;GRIN2D;GRIN2B;GLRA3;TRPV1;GLRB;GRIN3B;GRIA1;GRIN2C;GRIA4;GRIN3A;GLRA1 GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B;GRIN1 GO:0007612| learning PTGS2;GRIN1;GRIN2A;VDAC1 GO:0007611| learning or memory GRIN2A;CHRNA7;GRIN1;GRIN2B;CNR1 GO:0043523| regulation of neuron apoptosis GRIN1;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PLA2G1B;PPARG GO:0002576| platelet degranulation SOD1;ABCC4 GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;ABCB1;CACNA1I;TRPV4;TRPV1;TRPA1;ABCC1;CACNA1G;ABCC4;TRPV2;TRPV3;CACNA1H GO:0034220| ion transmembrane transport GRIN3B;GLRB;TRPV1;GRIA1;GRIA4;GRIN3A;GLRA1;TRPA1;GRIA2;CHRNA7;GRIA3;GLRA3 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2;ABCC4 GO:0006810| transport GRIA4;GRIN2C;ABCC1;CACNA1I;ABCB1;TRPV1;SLC7A7;ABCG2;GRIA3;GRIN2B;TRPV2;GRIN2A GO:0009611| response to wounding GRIN2A;GPX1;CYP1A1;GRIN2C GO:0042391| regulation of membrane potential GRIN2A;CACNA1H;GRIN1;GLRB;GLRA1;GRIN2C;CACNA1G GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;GPR12;HTR2A;GRIN1 GO:0043524| negative regulation of neuron apoptosis GRIN1;SOD1 GO:0007268| synaptic transmission GRIN2A;GRIA2;GRIN2B;HTR2A;GLRA3;OPRM1;OPRD1;VDAC1;GLRB;GRIA1;GLRA1;CACNA1G GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:0008542| visual learning GRIN1;HMGCR;GRIN2A GO:0016032| viral reproduction VDAC1;SLC1A5;HTR2A GO:0001964| startle response GLRA1;GLRB;GRIN2D;GRIN1;GRIN2A GO:0006816| calcium ion transport CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1;GRIN3A;TRPV2;GRIN2A;CHRNA7;TRPV3;GRIN1;CACNA1H GO:0045471| response to ethanol GRIN3A;CAT;GRIN2A;GRIN1;OPRM1;HMGCR;GRIN2B;CNR1;SOD1 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;GRIN1;CNR2;PTGS2;OPRM1;GRIN2A;TRPA1;TRPV1 GO:0030431| sleep GRIN2A;SLC29A1;HTR2A;CACNA1I GO:0060078| regulation of postsynaptic membrane potential GRIN2A;CHRNA7;GRIA1 GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0042428| serotonin metabolic process HTR1A;GRIN2A GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0008344| adult locomotory behavior OPRD1;GRIN2D;GRIN1 GO:0051930| regulation of sensory perception of pain GRIN2A;GRIN2D;OPRM1;OPRD1 GO:0006811| ion transport GRIN3A;GLRA1;TRPA1;GRIN2C;GRIA4;CACNA1G;TRPM8;TRPV1;VDAC1;CACNA1I;GRIN3B;TRPV4;GLRB;GRIA1;GRIN2B;GLRA3;CACNA1H;GRIA3;GRIN1;GRIN2D;TRPV3;CHRNA7;GRIN2A;TRPV2;GRIA2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACAT1;AANAT;ABCC4;PTGS2;CYP1A2 GO:0006812| cation transport GRIN1;TRPM8 GO:0043576| regulation of respiratory gaseous exchange GRIN1;GLRA1 GO:0007613| memory GRIN2A;CHRNA7;PTGS2;GRIN1;HTR2A;CNR1 GO:0022008| neurogenesis DAGLA;GRIN2A GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0001975| response to amphetamine SOD1;GRIN1;CNR2;GRIN2A GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0046718| entry of virus into host cell SLC1A5;HTR2A GO:0007165| signal transduction CACNA1I;PLA2G1B;GRIA1;PPARG;GPR18;SMPD1;CHRNA7;GRIA2;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0065009| regulation of molecular function GRIN2C;TRPV1;GRIN2B;GRIN1;GRIN2D;GRIN2A GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;TRPV3;CACNA1H;OPRM1;TRPM8;TRPV1;GRIN3B;TRPV4;CACNA1I;TRPA1;GRIN3A;CACNA1G GO:1900273| GRIN2A;CHRNA7 18158:[DB14011 DB08346] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08346|(5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE HSP90AB1 common genes common pathways GO:0001890| placenta development PPARG;HSP90AB1;SOD1 GO:0043524| negative regulation of neuron apoptosis HSP90AB1;SOD1 GO:0006805| xenobiotic metabolic process CYP2C9;HSP90AB1;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0042220| response to cocaine OPRM1;CNR1;HSP90AB1;SMPD1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG;HSP90AB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AB1;TRPV1 GO:0042493| response to drug SMPD1;ABCC1;HSP90AB1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0071407| cellular response to organic cyclic compound CYP1B1;HSP90AB1;CYP1A1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;HSP90AB1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AB1 18159:[DB14011 DB07678] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07678|(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;ESR1;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0048511| rhythmic process PPARG;NCOA2;AANAT GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;NCOA2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TRPV4;TRPV1;ESR1 GO:0007623| circadian rhythm NCOA2;AANAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG 18160:[DB14011 DB02169] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02169|9,10-Deepithio-9,10-Didehydroacanthifolicin PPP1CC common genes common pathways GO:0042752| regulation of circadian rhythm PPARG;PPP1CC GO:0048511| rhythmic process AANAT;PPARG;PPP1CC 18161:[DB14011 DB05790] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05790|SR 140333 TACR1 common genes common pathways GO:0035094| response to nicotine CNR1;TACR1;CHRNA7 GO:0048265| response to pain TACR1;TRPV1;TRPA1 GO:0043278| response to morphine OPRM1;TACR1;CNR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;TACR1;OPRM1 GO:0007611| learning or memory CHRNA7;TACR1;CNR1 GO:0010193| response to ozone CAT;TACR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;TACR1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PPARG;GPR18 GO:0032355| response to estradiol stimulus CYP1A2;TACR1;PTGS2;CAT GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;CNR2;PTGS2;TACR1;ALOX5;PTGS1 GO:0009408| response to heat TRPV1;TRPV2;SOD1;TACR1;TRPV3 GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;HTR2A;GLRA3;OPRD1;OPRM1;TACR1 GO:0019233| sensory perception of pain OPRM1;TACR1;PTGS2;CNR2;OPRD1;CNR1;HTR2A;TRPA1;TRPV1 GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1;TACR1 GO:0048266| behavioral response to pain TACR1;TRPV1 GO:0008217| regulation of blood pressure PPARG;PTGS2;TACR1;SOD1;PTGS1 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0045777| positive regulation of blood pressure TACR1;CNR1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;TACR1;PTGS2;PPARG;CYP1A1;TRPA1 GO:0042755| eating behavior OPRD1;OPRM1;TACR1 GO:0009725| response to hormone stimulus ACAT1;TACR1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;TACR1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;TACR1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TACR1;TRPV1;TRPV4 GO:0043117| positive regulation of vascular permeability TRPV4;TACR1 GO:0060083| smooth muscle contraction involved in micturition TRPV1;TACR1 18162:[DB14011 DB01429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes CYP2D6 common pathways GO:0006936| muscle contraction GLRA1;CACNA1H;CALM1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;ORM1;CHRNA7 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CALM1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;CACNA1H;TRPV3;CALM1;SCN5A;TRPV2 GO:0086002| CACNA1G;SCN5A GO:0086015| CACNA1G;SCN5A GO:0002576| platelet degranulation ORM1;CALM1;SOD1 GO:0035307| positive regulation of protein dephosphorylation CALM1;SMPD1 GO:0043312| neutrophil degranulation CAT;ALOX5;ORM1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0086016| SCN5A;CACNA1G GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;CYP2D6;DAGLA;FAAH GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;SCN5A GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN5A GO:0086046| CACNA1G;SCN5A GO:0086045| CACNA1G;SCN5A GO:0006811| ion transport CHRNA7;SCN5A;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;GLRA1;TRPA1;CACNA1G GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0002027| regulation of heart rate CACNA1G;SCN5A;CALM1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0086091| SCN5A;CACNA1G GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;SCN5A GO:0051100| negative regulation of binding CYP2D6 GO:0051592| response to calcium ion CALM1;AANAT GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0071277| cellular response to calcium ion SCN5A;ALOX15 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;IDO1;ORM1 GO:0086010| CACNA1H;SCN5A;CACNA1G;CACNA1I 18163:[DB14011 DB03892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03892|5-N-Allyl-Arginine NOS1 common genes common pathways GO:0071363| cellular response to growth factor stimulus TRPV1;NOS1;CAT;OPRD1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;NOS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NOS1;PPARG GO:0042311| vasodilation GPX1;NOS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NOS1 GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;NOS1;CYP1A1;CYP2C9;CRYZ;PTGS1;ALOX5;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0045454| cell redox homeostasis GSR;NOS1;GPX1 GO:0007520| myoblast fusion CACNA1H;NOS1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS1 GO:0006809| nitric oxide biosynthetic process NOS1;CYP1B1 GO:0033555| multicellular organismal response to stress NOS1;IDO1 GO:0045776| negative regulation of blood pressure CNR1;NOS1 GO:0042136| neurotransmitter biosynthetic process NOS1;DAGLA GO:0042738| exogenous drug catabolic process CYP2C9;NOS1;CYP2C19;CYP3A4;CYP1A2 GO:0009408| response to heat SOD1;TRPV3;TRPV2;NOS1;TRPV1 18164:[DB14011 DB08080] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08080|LATRUNCULIN B ACTA1;MKL1;SPIRE2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;MKL1 GO:0009612| response to mechanical stimulus PPARG;TRPV4;ACTA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MKL1;PLA2G1B;PPARG GO:0010628| positive regulation of gene expression ACTA1;TRPV4 GO:0048741| skeletal muscle fiber development ACTA1;GPX1 GO:0006936| muscle contraction ACTA1;CACNA1H;GLRA1 GO:0006351| transcription, DNA-dependent PPARG;MKL1 GO:0010226| response to lithium ion ACTA1;PTGS2 18165:[DB14011 DB09338] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0071320| cellular response to cAMP AQP1;PCK1;AANAT GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;AQP1;PTGS2 GO:0008152| metabolic process ACAT1;SMPD1;ALPL GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;SLC16A1;PCK1;GPX1;NAAA;PTGS1;PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0071260| cellular response to mechanical stimulus PTGS2;AQP1 GO:0033280| response to vitamin D PTGS2;ALPL GO:0032868| response to insulin stimulus CAT;PCK1;AANAT;TRPV4 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;AQP1 GO:0070301| cellular response to hydrogen peroxide AQP1;CYP1B1 GO:0014823| response to activity PCK1;CAT GO:0051384| response to glucocorticoid stimulus PTGS2;ALPL GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0032869| cellular response to insulin stimulus PCK1;PPARG;PLA2G1B GO:0001649| osteoblast differentiation CAT;ALPL GO:0034644| cellular response to UV PTGS2;AQP1 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;CAT;AQP1;SOD1;HTR2A;PTGS2;CYP1A2 GO:0071407| cellular response to organic cyclic compound CYP1B1;ALPL;CYP1A1;SLC16A1 GO:0032094| response to food CYP1A1;OPRM1;SLC16A1 GO:0032496| response to lipopolysaccharide PCK1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1;ALPL;IDO1;CYP1A1 GO:0033554| cellular response to stress OPRM1;AQP1 GO:0046677| response to antibiotic ALPL;CYP1A1;SOD1 GO:0071300| cellular response to retinoic acid PPARG;PCK1;AQP1 GO:0043066| negative regulation of apoptotic process AQP1;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0006884| cell volume homeostasis AQP1;TRPV4 GO:0055085| transmembrane transport TRPV2;AQP1;SLC16A1;CACNA1H;TRPV3;TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0045766| positive regulation of angiogenesis CHRNA7;AQP1;CYP1B1 GO:0050891| multicellular organismal water homeostasis AQP1;TRPV4 GO:0071356| cellular response to tumor necrosis factor PCK1;TRPV1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;PCK1;AQP1 GO:0007568| aging CYP1A1;PCK1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;PCK1;SLC16A1 GO:0033993| response to lipid PPARG;PCK1 GO:0071280| cellular response to copper ion CYP1A2;AQP1;CYP1A1 18166:[DB14011 DB07315] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways GO:0008152| metabolic process ACAT1;PYGL;SMPD1 GO:0042593| glucose homeostasis TRPV4;PPARG;PYGL;CNR1 GO:0043312| neutrophil degranulation PYGL;CAT;ALOX5 18167:[DB14011 DB09418] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0006810| transport ABCG2;TRPV1;CACNA1I;SLC5A5;ABCC1;TRPV2 GO:0098869| ALB;GSR;PTGS2;CAT;GPX1;PTGS1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;SLC5A5;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1 GO:0035725| sodium ion transmembrane transport SLC5A5;CACNA1G;CACNA1I;CACNA1H GO:0071320| cellular response to cAMP SLC5A5;AANAT GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;GLRA1;TRPA1;SLC5A5;CACNA1G GO:0001895| retina homeostasis ALB;SOD1 GO:0098656| VDAC1;SLC5A5 18168:[DB14011 DB06918] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06918|2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18169:[DB14011 DB04636] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04636|Glutamine t-butyl ester QPCT common genes common pathways GO:0043312| neutrophil degranulation QPCT;ALOX5;CAT 18170:[DB14011 DB06866] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06866|6-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 18171:[DB14011 DB04676] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04676|Dansyllysine IGHA2 common genes common pathways GO:0002376| immune system process IDO1;IGHA2 GO:0019731| antibacterial humoral response PLA2G1B;IGHA2 GO:0045087| innate immune response IGHA2;PPARG GO:0001895| retina homeostasis SOD1;IGHA2 GO:0006955| immune response CNR2;OPRD1;IGHA2 18172:[DB14011 DB07082] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07082|1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL NR1H2 common genes common pathways GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;NR1H2 GO:0055088| lipid homeostasis NR1H2;PPARG GO:0010887| negative regulation of cholesterol storage NR1H2;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation NR1H2;PPARG GO:0010629| negative regulation of gene expression NR1H2;OPRD1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1H2 GO:0006351| transcription, DNA-dependent NR1H2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NR1H2 GO:0045892| negative regulation of transcription, DNA-dependent NR1H2;PPARG GO:0010628| positive regulation of gene expression TRPV4;NR1H2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1H2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1H2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1H2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;NR1H2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NR1H2;PPARG 18173:[DB14011 DB05254] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways GO:0033629| negative regulation of cell adhesion mediated by integrin SERPINE1;CYP1B1 GO:0007623| circadian rhythm SERPINE1;AANAT GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0002576| platelet degranulation SOD1;SERPINE1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;PLA2G1B;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;PLAU GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;SERPINE1 GO:0001666| response to hypoxia CHRNA7;CAT;PLAU;CYP1A1 GO:0061045| negative regulation of wound healing HMGCR;SERPINE1 GO:0001525| angiogenesis CYP1B1;SERPINE1;PTGS2 GO:0030336| negative regulation of cell migration SERPINE1;CYP1B1 GO:1902042| SERPINE1;GPX1 GO:0050729| positive regulation of inflammatory response TRPV4;SERPINE1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;PLAU;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7 18174:[DB14011 DB03276] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways GO:0007568| aging CAT;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;GRB2;CYP1A1 GO:0030838| positive regulation of actin filament polymerization GRB2;ALOX15 GO:0042127| regulation of cell proliferation GRB2;PTGS1;PTGS2 GO:0045087| innate immune response PPARG;GRB2 GO:0051897| positive regulation of protein kinase B signaling cascade GRB2;GPX1 GO:0065009| regulation of molecular function GRB2;TRPV1 GO:0051291| protein heterooligomerization GLRB;GRB2;GLRA1 GO:0016032| viral reproduction GRB2;VDAC1;HTR2A 18175:[DB14011 DB01127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1I2;PLA2G1B GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2;CYP2E1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;PPARG GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;CYP2E1;PTGS2;CYP1A2;CAT GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG GO:0022900| electron transport chain CYP1A2;CYP19A1;IDO1;GSR GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CYP19A1;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP2E1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0010243| response to organic nitrogen CYP2E1;PTGS2;TRPV1 GO:0006694| steroid biosynthetic process CYP17A1;CYP19A1;HMGCR GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;PPARG GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;NR1I2;CYP2C9;CYP1A1;CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0036378| CYP3A4 GO:0010193| response to ozone CYP2E1;CAT GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0045471| response to ethanol CAT;CNR1;SOD1;CYP2E1;HMGCR;OPRM1 GO:0006351| transcription, DNA-dependent PPARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;NR1I2;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;NR1I2;CYP2C9;CYP2C19 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0042908| xenobiotic transport ABCG2;ABCC1;NR1I2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;NR1I2;GPR18;SMPD1 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT 18176:[DB14011 DB02552] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0008299| isoprenoid biosynthetic process GGPS1;HMGCR;FDPS GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;FDPS;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;FDPS GO:0008203| cholesterol metabolic process HMGCR;CAT;FDPS GO:0006695| cholesterol biosynthetic process HMGCR;FDPS;GGPS1 GO:0016032| viral reproduction VDAC1;HTR2A;FDPS GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;FDPS;GPX1;NAAA;PTGS1;CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 18177:[DB14011 DB08699] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways GO:0035556| intracellular signal transduction PLA2G1B;CAMK2G GO:0007399| nervous system development GLRB;SMPD1;CAMK2G GO:0006816| calcium ion transport CAMK2G;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1 GO:0051924| regulation of calcium ion transport CAMK2G;OPRD1 GO:0065009| regulation of molecular function CAMK2G;TRPV1 18178:[DB14011 DB00380] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0043065| positive regulation of apoptotic process PPARG;TOP2A;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0042752| regulation of circadian rhythm TOP2A;PPARG 18179:[DB14011 DB07916] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;CASP1;CACNA1I;PLA2G1B GO:0006919| activation of caspase activity CASP1;PPARG GO:0050727| regulation of inflammatory response PTGS2;CASP1 GO:0071260| cellular response to mechanical stimulus CASP1;PTGS2 GO:0006915| apoptotic process VDAC1;CASP1;GPX1 GO:0001666| response to hypoxia CASP1;CYP1A1;CHRNA7;CAT GO:0032496| response to lipopolysaccharide CYP1A1;CASP1;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 18180:[DB14011 DB02218] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02218|N-[4-hydroxymethyl-cyclohexan-6-yl-1,2,3-triol]-4,6-dideoxy-4-aminoglucopyranoside AMY2A;AMY2B;AMY2A common genes common pathways GO:0008152| metabolic process SMPD1;AMY2B;AMY2A;ACAT1 18181:[DB14011 DB03800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways GO:0007568| aging CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CYP1A1;TYMS GO:0007623| circadian rhythm TYMS;AANAT GO:0034097| response to cytokine stimulus PTGS2;AANAT;TYMS GO:0032259| methylation TYMS;CYP1A2 GO:0042493| response to drug TRPA1;PPARG;TYMS;CYP1A1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0033189| response to vitamin A CAT;PPARG;CYP1A1;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS GO:0009636| response to toxin GPX1;CAT;CYP1A1;TYMS;CYP1B1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TYMS;CYP1A1;PPARG;TRPA1 GO:0045471| response to ethanol TYMS;CAT;CNR1;SOD1;HMGCR;OPRM1 18182:[DB14011 DB03956] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways GO:0001525| angiogenesis CYP1B1;PLCD1;PTGS2 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;PLCD1;CYP2D6;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0035556| intracellular signal transduction PLCD1;PLA2G1B GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;PLCD1;SMPD1;PPARG;GPR18 GO:0042127| regulation of cell proliferation PLCD1;PTGS2;PTGS1 GO:0016042| lipid catabolic process PLA2G1B;DAGLA;PLCD1;NAPEPLD GO:0006644| phospholipid metabolic process PLA2G1B;PLCD1;NAPEPLD 18183:[DB14011 DB02665] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02665|(1R,2S)-2-Phenylcyclopropanaminium PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18184:[DB14011 DB02673] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development ACHE;CACNA1H GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development ACHE;SMPD1;GLRB GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 18185:[DB14011 DB07356] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0007155| cell adhesion DPP4;CYP1B1 GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 18186:[DB14011 DB07946] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07946|N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide F2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;F2;PPARG;GPR18 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0008284| positive regulation of cell proliferation F2;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0061844| F2;PLA2G1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 18187:[DB14011 DB05052] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05052|MF101 ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG GO:0006351| transcription, DNA-dependent PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR2 GO:0007165| signal transduction ESR2;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;ESR2 18188:[DB14011 DB06243] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06243|Eflornithine ODC1 common genes common pathways GO:0001822| kidney development ODC1;CAT GO:0008284| positive regulation of cell proliferation CHRNA7;ODC1;HTR2A;HTR1A;HMGCR;PTGS2 GO:0009615| response to virus CYP1A1;ODC1 18189:[DB14011 DB00195] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes CYP2D6;CYP1A2 common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0007165| signal transduction PLA2G1B;CACNA1I;ADRB1;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;ADRB2;CNR1;GPR12;HTR2A GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0045453| bone resorption GPR55;ADRB2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;CYP1A2;PTGS2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0050873| brown fat cell differentiation ADRB1;PTGS2;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPV1;TRPA1 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1;ADRB1 GO:0009409| response to cold PPARG;TRPA1;ADRB1;TRPM8;ADRB2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;ADRB1;HTR1A;GPR55;HTR2A;GPR12;CNR1;ADRB2;OPRM1;CNR2;OPRD1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0002024| diet induced thermogenesis ADRB2;TRPV4;ADRB1;TRPV1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PLA2G1B;PPARG GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0032259| methylation CYP1A2 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0019369| arachidonic acid metabolic process FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 18190:[DB14011 DB03032] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03032|S-Octylglutathione GSTM4 common genes common pathways GO:0042178| xenobiotic catabolic process CRYZ;GSTM4 GO:0006749| glutathione metabolic process GSR;GSTM4;GPX1;SOD1 GO:0008152| metabolic process GSTM4;ACAT1;SMPD1 18191:[DB14011 DB03628] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03628|ISO24 SRC common genes common pathways GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;SRC GO:0002376| immune system process IDO1;SRC GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;SRC;SOD1;HTR2A;PTGS2;CYP1A2 GO:0016236| macroautophagy SRC;VDAC1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response SRC;PPARG GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;SRC;GPX1;CAT GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1 GO:0008283| cell proliferation GPX1;SRC;HTR1A;CYP1A1 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;SRC;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0070542| response to fatty acid PTGS2;CAT;SRC GO:0045453| bone resorption SRC;GPR55 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0031667| response to nutrient levels SRC;SOD1 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SRC;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042542| response to hydrogen peroxide TRPA1;CAT;SRC;GPX1;SOD1 GO:0035556| intracellular signal transduction PLA2G1B;SRC 18192:[DB14011 DB04789] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;ABCC2 GO:0007565| female pregnancy ABCC2;IDO1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCC1 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;ABCC2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0032259| methylation CYP1A2;AMT GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;ABCC2;IDO1;CYP1A1 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;ABCC2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2;ABCC2 GO:0006810| transport ABCC2;ABCG2;CACNA1I;TRPV1;ABCC1;TRPV2 18193:[DB14011 DB07893] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07893|PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE IGKC common genes common pathways GO:0001895| retina homeostasis SOD1;IGKC GO:0006955| immune response IGKC;CNR2;OPRD1 GO:0002376| immune system process IDO1;IGKC GO:0045087| innate immune response IGKC;PPARG 18194:[DB14011 DB02979] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02979|N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane NOS3 common genes common pathways GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 GO:0030324| lung development CYP1A2;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0042311| vasodilation NOS3;GPX1 GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;NOS3;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0045454| cell redox homeostasis NOS3;GSR;GPX1 GO:0006809| nitric oxide biosynthetic process NOS3;CYP1B1 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:1902042| GPX1;NOS3 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;NOS3;PPARG GO:0001525| angiogenesis PTGS2;CYP1B1;NOS3 GO:0045776| negative regulation of blood pressure NOS3;CNR1 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1;NOS3 18195:[DB14011 DB06448] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06448|Lonafarnib FNTA;IGFBP3 common genes common pathways GO:0006915| apoptotic process GPX1;IGFBP3;VDAC1 GO:0008285| negative regulation of cell proliferation IGFBP3;OPRM1;PTGS2;CYP1B1;PPARG GO:0001649| osteoblast differentiation CAT;IGFBP3 GO:0048662| negative regulation of smooth muscle cell proliferation IGFBP3;PPARG GO:0043065| positive regulation of apoptotic process IGFBP3;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG 18196:[DB14011 DB06933] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06933|N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide MAPK10 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;MAPK10;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0042752| regulation of circadian rhythm MAPK10;PPARG GO:0009416| response to light stimulus AANAT;MAPK10 GO:0048511| rhythmic process PPARG;MAPK10;AANAT GO:0000187| activation of MAPK activity MAPK10;PLA2G1B;CHRNA7;SOD1 GO:0010468| regulation of gene expression MAPK10;CYP1A2 18197:[DB14011 DB04540] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes ABCG2 common pathways GO:0006955| immune response CNR2;OPRD1;CLEC4E GO:0006816| calcium ion transport VDR;TRPV2;CHRNA7;TRPV3;CACNA1H;TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;TRPA1 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0042752| regulation of circadian rhythm PPARG;RORA GO:0007595| lactation SLC29A1;VDR GO:0046415| urate metabolic process ABCG2 GO:0006805| xenobiotic metabolic process RORA;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;RORA;PTGS2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RORA;NR1I3;VDR GO:0006351| transcription, DNA-dependent VDR;NR1I3;PPARG;RORA GO:0001525| angiogenesis CYP1B1;RORA;PTGS2 GO:0008285| negative regulation of cell proliferation VDR;PTGS2;OPRM1;CYP1B1;PPARG GO:0006809| nitric oxide biosynthetic process RORA;CYP1B1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;VDR;CHRNA7;OPRD1;NR1I3;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0050728| negative regulation of inflammatory response RORA;CNR2 GO:0015886| heme transport ABCG2 GO:0006367| transcription initiation from RNA polymerase II promoter RORA;PPARG;VDR;NR1I3 GO:0045893| positive regulation of transcription, DNA-dependent RORA;PPARG GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCB1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG;RORA;VDR;NR1I3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;NR1I3;PLA2G1B;PPARG;RORA GO:0045087| innate immune response CLEC4E;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;VDR GO:0007623| circadian rhythm RORA;AANAT GO:0033344| cholesterol efflux ABCG2 GO:0010628| positive regulation of gene expression VDR;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I3;VDR GO:0048511| rhythmic process AANAT;PPARG;RORA GO:0071356| cellular response to tumor necrosis factor TRPV1;RORA GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;TRPV4;ABCB1;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G;TRPV2;TRPV3;CACNA1H GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;HTR2A;GPR12;CHRNA7;VDR GO:0002376| immune system process CLEC4E;IDO1 GO:0060850| regulation of transcription involved in cell fate commitment PPARG;RORA GO:0006810| transport ABCG2;TRPV1;ABCB1;CACNA1I;ABCC1;TRPV2 GO:0046697| decidualization PTGS2;VDR GO:0071456| cellular response to hypoxia RORA;PTGS2;OPRD1;SLC29A1 18198:[DB14011 DB12445] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12445|Nitroaspirin PTGS1 common genes PTGS1 common pathways GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| CAT;GPX1;PTGS1;PTGS2;GSR GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ALOX5;PTGS1;CNR2;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1;PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B 18199:[DB14011 DB02381] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02381|nor-NOHA ARG1 common genes common pathways GO:0007565| female pregnancy ARG1;IDO1 GO:0009635| response to herbicide CYP1A1;ARG1 GO:0048678| response to axon injury SOD1;ARG1 GO:0001889| liver development CYP1A1;ACAT1;ARG1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;ARG1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ARG1 GO:0010043| response to zinc ion ARG1;AANAT GO:0010269| response to selenium ion ARG1;GPX1 GO:0043434| response to peptide hormone stimulus TRPV1;ARG1 GO:0033189| response to vitamin A ARG1;CAT;CYP1A1;PPARG GO:0010042| response to manganese ion PTGS2;ARG1 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;ARG1;CAT;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2 GO:0043312| neutrophil degranulation ARG1;CAT;ALOX5 GO:0045087| innate immune response ARG1;PPARG GO:0070207| protein homotrimerization ARG1;TRPM8 GO:0030324| lung development ARG1;CYP1A2 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E ARG1;CAT GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;ARG1;CYP1A1;IDO1 GO:0042130| negative regulation of T cell proliferation IDO1;ARG1 GO:0043200| response to amino acid stimulus ARG1;GLRA3;GLRB GO:0046686| response to cadmium ion CAT;ARG1 GO:0002376| immune system process IDO1;ARG1 GO:0007568| aging NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;ARG1;CAT;CYP1A1 GO:0009611| response to wounding CYP1A1;GPX1;ARG1 18200:[DB14011 DB14540] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCG2;CYP3A4;CYP3A5;CYP3A7 common pathways GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ANXA1 GO:0033344| cholesterol efflux ABCG2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PLA2G1B;PPARG GO:0045087| innate immune response ANXA1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;NR3C1 GO:0032094| response to food OPRM1;HSD11B2;CYP1A1 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;HSD11B2;ABCG2;ANXA1;ABCB1;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0032342| aldosterone biosynthetic process CYP11B1;CYP11B2;CACNA1H GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;HSD11B2;CYP3A5;ALOX15;HSD3B1;CYP2D6;CYP2C19;CYP2C8;IDO1;GSR;CYP3A7;PTGS2;CYP1A2;CYP11B1;CYP11B2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0006694| steroid biosynthetic process CYP11B1;HMGCR;CYP11B2;CYP17A1;HSD3B1 GO:0015886| heme transport ABCG2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;CYP11B2;HMGCR;CYP11B1;CYP17A1;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1B1;CYP1A1;CYP2C9 GO:0032355| response to estradiol stimulus ANXA1;CAT;CYP1A2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;ANXA1;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0006810| transport TRPV2;ABCC1;ABCG2;TRPV1;ABCB1;CACNA1I GO:0042593| glucose homeostasis CNR1;CYP11B1;PPARG;TRPV4 GO:0002376| immune system process ANXA1;IDO1 GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B2;HSD3B1;CYP11B1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP1A2 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8;CYP1A1 GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0031532| actin cytoskeleton reorganization ANXA1;TRPV4 GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPV1;VDAC1;CACNA1I;ABCB1;TRPV4;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;SLCO1A2;TRPV3;CACNA1H;SLC22A8 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia HSD11B2;CYP1A1;CHRNA7;CAT GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger ANXA1;CNR1;OPRD1;CNR2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0007166| cell surface receptor linked signaling pathway TRPA1;ANXA1;TRPV1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C8;CYP2C19;CYP3A5 GO:0008152| metabolic process ACAT1;SMPD1;HSD3B1 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP11B2;CYP11B1 GO:0050727| regulation of inflammatory response ANXA1;PTGS2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;ANXA1;PTGS2;SOD1;CNR1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;CYP11B2;CYP11B1;CYP1A2;PTGS2;PTGS1;NAAA;GPX1;PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C8;CYP2C19 GO:0046415| urate metabolic process ABCG2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;PTGS2 GO:0007565| female pregnancy HSD11B2;IDO1 GO:0008209| androgen metabolic process CYP3A4 GO:0006955| immune response CYP11B1;OPRD1;CNR2 GO:0006954| inflammatory response IDO1;ALOX15;ANXA1;TRPV1;CNR2;PTGS2;PTGS1;ALOX5 GO:0034651| cortisol biosynthetic process CYP11B2;CYP11B1;CACNA1H GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0043434| response to peptide hormone stimulus TRPV1;ANXA1 GO:1900087| ANXA1;CYP1A1 GO:0051384| response to glucocorticoid stimulus ANXA1;HSD11B2;PTGS2 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0050482| arachidonic acid secretion ANXA1;PLA2G1B GO:0032870| cellular response to hormone stimulus CYP11B2;CYP11B1;CACNA1H GO:0044849| OPRM1;ANXA1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2C8;CYP2D6 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2C8;CYP1B1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;NR3C1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;ANXA1 GO:0009725| response to hormone stimulus ANXA1;ACAT1 GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;ANXA1;TRPA1;PPARG;CYP1A1 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;SLCO1A2;SLC22A8;GLRA3;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;ANXA1 GO:0006702| androgen biosynthetic process CYP17A1;HSD3B1 GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4;HSD11B2 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0098656| SLC22A8;VDAC1 GO:0070365| hepatocyte differentiation ANXA1;CYP1A1 GO:0008217| regulation of blood pressure PPARG;PTGS1;CYP11B1;PTGS2;SOD1 GO:0035865| cellular response to potassium ion SOD1;CACNA1H;CYP11B1;CYP11B2 GO:0046883| regulation of hormone secretion ANXA1;HTR2A;HTR1A GO:0070301| cellular response to hydrogen peroxide CYP1B1;ANXA1 18201:[DB14011 DB05301] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05301|LAX-101 PLD1;CASP1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;PTGS1;GPX1;PLD1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0050727| regulation of inflammatory response CASP1;PTGS2 GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;CASP1;GPR18;PPARG;SMPD1 GO:0006919| activation of caspase activity CASP1;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;PLD1 GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLD1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;CYP1A1;CASP1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;CASP1 GO:0006915| apoptotic process CASP1;VDAC1;GPX1 GO:0016042| lipid catabolic process PLD1;NAPEPLD;PLA2G1B;DAGLA 18202:[DB14011 DB07421] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;AR GO:0008283| cell proliferation CYP1A1;AR;GPX1;HTR1A GO:0007548| sex differentiation CYP17A1;AR GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;AR;CHRNA7 GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;AR;CHRNA7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV4;TRPV1 GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport TRPV2;AR;TRPV1;CACNA1I;ABCG2;ABCC1 18203:[DB14011 DB03088] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03088|Pidolic Acid VEGFA;AMY2A;IGLC1;TFF2;cycA;ADAM28;KRTAP5-2;HCRT;CCL8;AMY2B;ANG;AMY1A;AMY2A common genes common pathways GO:0032431| activation of phospholipase A2 activity PLA2G1B;ANG GO:0007283| spermatogenesis CNR1;SOD1;ADAM28 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;VEGFA;ANG GO:0010628| positive regulation of gene expression TRPV4;VEGFA GO:0007202| activation of phospholipase C activity HTR2A;GPR55;ANG GO:0071356| cellular response to tumor necrosis factor TRPV1;CCL8 GO:0043406| positive regulation of MAP kinase activity VEGFA;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;CCL8;HMGCR;VEGFA;OPRM1 GO:0001541| ovarian follicle development VEGFA;ANG;SOD1 GO:0045766| positive regulation of angiogenesis CHRNA7;VEGFA;CYP1B1 GO:0050714| positive regulation of protein secretion PLA2G1B;ANG GO:0030855| epithelial cell differentiation VEGFA;PPARG;VDAC1 GO:0002376| immune system process IGLC1;IDO1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CCL8;HTR2A;GPR12;CHRNA7 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway HCRT;CCL8;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;GPR18;PPARG GO:0071456| cellular response to hypoxia OPRD1;PTGS2;VEGFA;SLC29A1 GO:0030593| neutrophil chemotaxis PLA2G1B;CCL8 GO:0050830| defense response to Gram-positive bacterium ANG;PLA2G1B GO:0051970| negative regulation of transmission of nerve impulse HCRT;GLRA1 GO:0030224| monocyte differentiation PPARG;VEGFA GO:0019731| antibacterial humoral response ANG;PLA2G1B GO:0009615| response to virus CCL8;CYP1A1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;VEGFA;PTGS2;HMGCR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;VEGFA GO:0007218| neuropeptide signaling pathway HCRT;GLRA3;OPRM1;OPRD1;GLRB;GLRA1 GO:0002576| platelet degranulation VEGFA;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;VEGFA;CAT;GPX1 GO:0001822| kidney development VEGFA;CAT GO:0045087| innate immune response IGLC1;PPARG;ANG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;TRPV4;TRPV1 GO:0042060| wound healing ALOX15;TFF2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;TRPV1;OPRM1;GLRA3;SLC29A1;HCRT;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;HCRT GO:0030324| lung development VEGFA;CYP1A2 GO:0051781| positive regulation of cell division CAT;VEGFA GO:0001890| placenta development PPARG;ANG;SOD1 GO:0061844| PLA2G1B;CCL8;ANG GO:0042755| eating behavior OPRD1;OPRM1;HCRT GO:0043267| negative regulation of potassium ion transport HTR2A;HCRT GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;ANG GO:0009725| response to hormone stimulus ANG;ACAT1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;CCL8;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;HCRT;TRPV4;TRPV1 GO:0043117| positive regulation of vascular permeability VEGFA;TRPV4 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;CCL8;TRPV1;ALOX15;IDO1 GO:0006816| calcium ion transport CHRNA7;TRPV2;CACNA1H;TRPV3;CCL8;TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G GO:0006955| immune response IGLC1;OPRD1;CCL8;CNR2 GO:0007595| lactation VEGFA;SLC29A1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;HTR2A;GLRA3;OPRD1;OPRM1;HCRT GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;VEGFA;PTGS2 GO:0001659| temperature homeostasis TRPV1;HCRT;GPX1;HTR2A GO:0008152| metabolic process AMY1A;ACAT1;AMY2A;AMY2B;SMPD1 GO:0007399| nervous system development VEGFA;GLRB;SMPD1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;VEGFA GO:0001525| angiogenesis CYP1B1;ANG;PTGS2;VEGFA GO:0048469| cell maturation VEGFA;PPARG 18204:[DB14011 DB08173] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08173|5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 18205:[DB14011 DB05509] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05509|LI-301 OPRM1;HTR1A common genes HTR1A;OPRM1 common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;GLRB;TRPV1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0042060| wound healing ALOX15;OPRM1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CYP1A1;IDO1 GO:0033554| cellular response to stress OPRM1 GO:0050795| regulation of behavior HTR1A;HTR2A GO:0070848| response to growth factor stimulus OPRM1 GO:0007626| locomotory behavior SOD1;OPRM1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRM1;OPRD1;GLRA1;GLRB GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0032094| response to food OPRM1;CYP1A1 GO:0035640| exploration behavior HTR1A GO:0032100| positive regulation of appetite OPRM1 GO:0043278| response to morphine CNR1;OPRM1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0007210| serotonin receptor signaling pathway HTR1A;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0050769| positive regulation of neurogenesis OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1 GO:0042220| response to cocaine SMPD1;CNR1;OPRM1 GO:0014062| regulation of serotonin secretion HTR1A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0045471| response to ethanol CAT;SOD1;CNR1;OPRM1;HMGCR GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0042310| vasoconstriction HTR1A GO:0042428| serotonin metabolic process HTR1A GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;VDAC1;GLRB;CACNA1G;GLRA1 GO:0048149| behavioral response to ethanol OPRM1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0007600| sensory perception OPRM1;TRPV2 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007610| behavior HTR1A;HTR2A GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0044849| OPRM1 GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;OPRM1;CACNA1H;TRPV3;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1 GO:0042755| eating behavior OPRD1;OPRM1 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0001662| behavioral fear response HTR1A;VDAC1 GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0042053| regulation of dopamine metabolic process HTR1A 18206:[DB14011 DB04741] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04741|Myxothiazol UQCRC1 common genes common pathways GO:0014823| response to activity CAT;UQCRC1 GO:0009060| aerobic respiration CAT;UQCRC1 GO:0055114| oxidation-reduction process CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;UQCRC1;CYP1A1;CYP2C9;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 18207:[DB14011 DB08507] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08507|N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID MMP3 common genes common pathways 18208:[DB14011 DB14503] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0046686| response to cadmium ion CAT;SLC34A1 GO:0055085| transmembrane transport SLC20A1;CACNA1H;TRPV3;SLC20A2;TRPV2;SLC34A3;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;SLC34A2 GO:0051260| protein homooligomerization GLRA1;GLRA3;SLC34A1;ACAT1 GO:0032355| response to estradiol stimulus SLC34A1;CAT;PTGS2;CYP1A2 GO:0006810| transport TRPV2;SLC20A2;SLC20A1;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0033189| response to vitamin A PPARG;CYP1A1;SLC34A1;CAT GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;CAT;SLC34A1;SOD1;HTR2A;CYP1A2;PTGS2 GO:0001822| kidney development SLC34A1;CAT GO:0010288| response to lead ion SLC34A1;CAT GO:0007584| response to nutrient PPARG;HMGCR;CNR1;SLC34A1 GO:0043627| response to estrogen stimulus SLC34A2;PPARG GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;SLC34A2;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA3;SLC20A1;TRPV3;CACNA1H;SLC20A2;CHRNA7;SLC34A1;TRPV2;SLC34A3 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;SLC20A1;HTR1A;GPR12;CNR1;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0043434| response to peptide hormone stimulus SLC34A1;TRPV1 GO:0046718| entry of virus into host cell HTR2A;SLC20A2 GO:0016032| viral reproduction VDAC1;HTR2A;SLC20A2 GO:0001503| ossification ALOX15;SLC34A1 GO:0035725| sodium ion transmembrane transport SLC20A2;SLC34A3;SLC34A1;SLC20A1;CACNA1H;CACNA1I;SLC34A2;CACNA1G 18209:[DB14011 DB05984] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05984|RAF-265 KDR;BRAF common genes common pathways GO:0051291| protein heterooligomerization GLRA1;BRAF;GLRB GO:0043434| response to peptide hormone stimulus TRPV1;BRAF GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;BRAF;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation BRAF;OPRD1;PTGS2 GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0043524| negative regulation of neuron apoptosis SOD1;BRAF GO:0008542| visual learning BRAF;HMGCR GO:0016032| viral reproduction VDAC1;KDR;HTR2A GO:0001525| angiogenesis KDR;CYP1B1;PTGS2 GO:0071277| cellular response to calcium ion ALOX15;BRAF GO:1990090| BRAF;TRPV1 GO:0035556| intracellular signal transduction PLA2G1B;BRAF GO:0045766| positive regulation of angiogenesis CYP1B1;KDR;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;BRAF;KDR GO:0051591| response to cAMP BRAF;AANAT GO:0015758| glucose transport PLA2G1B;BRAF GO:0010628| positive regulation of gene expression BRAF;TRPV4 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0048538| thymus development SOD1;BRAF GO:0042127| regulation of cell proliferation PTGS1;PTGS2;BRAF GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;KDR;BRAF GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;KDR 18210:[DB14011 DB02029] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways GO:0009636| response to toxin CYP1A1;CYP1B1;EPHX2;CAT;GPX1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;EPHX2;PPARG GO:0072593| reactive oxygen species metabolic process SOD1;EPHX2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;CNR2;PTGS2;EPHX2;PTGS1;ALOX5 GO:0006629| lipid metabolic process EPHX2;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;PTGS1;NAAA;GPX1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B GO:0006805| xenobiotic metabolic process EPHX2;CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0008152| metabolic process SMPD1;EPHX2;ACAT1 GO:0010628| positive regulation of gene expression EPHX2;TRPV4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;EPHX2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;EPHX2;TRPM8;TRPV4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;EPHX2;CYP1A2 18211:[DB14011 DB05714] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05714|Flovagatran F2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;F2 GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 18212:[DB14011 DB11601] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11601|Tuberculin Purified Protein Derivative TLR2 common genes common pathways GO:0050830| defense response to Gram-positive bacterium TLR2;PLA2G1B GO:0006691| leukotriene metabolic process ALOX5;ABCC1;TLR2;ALOX15 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TLR2 GO:0043312| neutrophil degranulation TLR2;ALOX5;CAT GO:0045087| innate immune response PPARG;TLR2 GO:0007612| learning PTGS2;TLR2;VDAC1 GO:0032496| response to lipopolysaccharide TLR2;CYP1A1;IDO1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0010628| positive regulation of gene expression TRPV4;TLR2 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;TLR2 GO:0048714| positive regulation of oligodendrocyte differentiation TLR2;PPARG GO:0006915| apoptotic process GPX1;TLR2;VDAC1 GO:0002376| immune system process IDO1;TLR2 GO:0032735| positive regulation of interleukin-12 production TLR2;IDO1 GO:0006955| immune response TLR2;OPRD1;CNR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;TLR2 GO:0006954| inflammatory response TLR2;TRPV1;ALOX15;IDO1;PTGS2;CNR2;ALOX5;PTGS1 GO:0001774| microglial cell activation TLR2;TRPV1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;TLR2 GO:0009636| response to toxin CAT;GPX1;CYP1B1;CYP1A1;TLR2 GO:0032868| response to insulin stimulus TLR2;TRPV4;CAT;AANAT GO:0070542| response to fatty acid CAT;PTGS2;TLR2 GO:0007165| signal transduction SMPD1;GPR18;PPARG;TLR2;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7 GO:0050729| positive regulation of inflammatory response TRPV4;TLR2 18213:[DB14011 DB03896] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03896|Triphosphoric acid PAPOLA common genes common pathways 18214:[DB14011 DB03860] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR2;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ESR2;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2 GO:0006351| transcription, DNA-dependent PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG GO:0007165| signal transduction ESR2;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 18215:[DB14011 DB01228] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01228|Encainide SCN5A;CYP2D6 common genes CYP2D6 common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;DAGLA;CYP2D6;ALOX15 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0086016| SCN5A;CACNA1G GO:0086015| SCN5A;CACNA1G GO:0086002| SCN5A;CACNA1G GO:0055085| transmembrane transport TRPV3;CACNA1H;SCN5A;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0086010| CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0086091| SCN5A;CACNA1G GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0051100| negative regulation of binding CYP2D6 GO:0035725| sodium ion transmembrane transport CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0071277| cellular response to calcium ion ALOX15;SCN5A GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0002027| regulation of heart rate SCN5A;CACNA1G GO:0086045| SCN5A;CACNA1G GO:0006811| ion transport SCN5A;CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPA1;GLRA1;CACNA1G GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN5A;CACNA1G GO:0086046| CACNA1G;SCN5A GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;SCN5A 18216:[DB14011 DB01651] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01651|Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside APCS common genes common pathways GO:0002674| negative regulation of acute inflammatory response PPARG;APCS GO:0045087| innate immune response APCS;PPARG GO:0061045| negative regulation of wound healing APCS;HMGCR 18217:[DB14011 DB02559] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CRYZ;DHFR;CYP2C9;CYP1A1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;PTGS1;ALOX5;GPX1 18218:[DB14011 DB02222] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0006955| immune response PNP;CNR2;OPRD1 GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0043312| neutrophil degranulation CAT;ALOX5;PNP GO:0042493| response to drug ABCC1;SMPD1;PPARG;PNP;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT 18219:[DB14011 DB07111] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes PPARG common pathways GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG;GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4 GO:0051974| negative regulation of telomerase activity PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1 GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0071300| cellular response to retinoic acid PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0045087| innate immune response PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0042594| response to starvation ACAT1;PPARG GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 18220:[DB14011 DB00707] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00707|Porfimer sodium LDLR;FCGR1A common genes common pathways GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;FCGR1A;SMPD1;PPARG;GPR18 GO:0050729| positive regulation of inflammatory response TRPV4;LDLR GO:0046718| entry of virus into host cell LDLR;HTR2A GO:0006955| immune response CNR2;OPRD1;FCGR1A GO:0016032| viral reproduction HTR2A;VDAC1;LDLR GO:0010629| negative regulation of gene expression LDLR;OPRD1 GO:0006629| lipid metabolic process LDLR;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1 GO:0010628| positive regulation of gene expression LDLR;TRPV4 GO:0002376| immune system process IDO1;FCGR1A GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;LDLR;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;LDLR GO:0045087| innate immune response PPARG;FCGR1A GO:0008203| cholesterol metabolic process CAT;HMGCR;LDLR 18221:[DB14011 DB06241] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06241|Clenoliximab CD4 common genes common pathways GO:0007155| cell adhesion CD4;CYP1B1 GO:0010524| positive regulation of calcium ion transport into cytosol CD4;PLA2G1B GO:0045893| positive regulation of transcription, DNA-dependent CD4;PPARG GO:0002376| immune system process IDO1;CD4 GO:0032355| response to estradiol stimulus CAT;CD4;PTGS2;CYP1A2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;CD4;HMGCR GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;CD4 GO:0006955| immune response CNR2;CD4;OPRD1 GO:0016032| viral reproduction HTR2A;CD4;VDAC1 GO:0030217| T cell differentiation GPR18;CD4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD4 GO:0051924| regulation of calcium ion transport CD4;OPRD1 GO:0033674| positive regulation of kinase activity HTR2A;CD4 GO:0001934| positive regulation of protein phosphorylation CD4;CHRNA7 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CD4;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0033280| response to vitamin D PTGS2;CD4 18222:[DB14011 DB03135] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03135|[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid TPI1 common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;TPI1 18223:[DB14011 DB02126] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways GO:0042744| hydrogen peroxide catabolic process HBB;HBA1;CAT;GPX1 GO:0098869| GSR;HBA1;HBB;CAT;PTGS1;GPX1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;HBB;TRPV1 GO:0043312| neutrophil degranulation ALOX5;CAT;HBB GO:0008217| regulation of blood pressure PPARG;HBB;PTGS2;SOD1;PTGS1 GO:0051291| protein heterooligomerization GLRB;HBA1;GLRA1;HBB GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB GO:0042542| response to hydrogen peroxide HBB;TRPA1;HBA1;SOD1;GPX1;CAT 18224:[DB14011 DB01252] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes PPARG common pathways GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2;UGT1A3 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;ABCC8;TRPV2 GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0042594| response to starvation ACAT1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0030308| negative regulation of cell growth PPARG GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;ABCC8;CNR2;PTGS2;OPRM1;CYP1A2 GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0032526| response to retinoic acid PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0016525| negative regulation of angiogenesis ABCC8;PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0099133| ABCC8;ABCC1 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug CAT;ABCC8;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1 GO:0030224| monocyte differentiation PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction OPRD1;CNR2;OPRM1;ABCC8;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:1905461| PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0050796| regulation of insulin secretion CNR1;ABCC8 GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0007613| memory CNR1;HTR2A;ABCC8;PTGS2;CHRNA7 GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0010043| response to zinc ion ABCC8;AANAT GO:0055088| lipid homeostasis PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT;ABCC8 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0008152| metabolic process SMPD1;ACAT1;UGT1A3;UGT2B7 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process UGT2B7;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0061045| negative regulation of wound healing HMGCR;ABCC8 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0048469| cell maturation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0009268| response to pH ABCC8;TRPV1 GO:0008542| visual learning ABCC8;HMGCR GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0007565| female pregnancy IDO1;ABCC8 GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0008209| androgen metabolic process UGT2B7;CYP3A4 18225:[DB14011 DB08214] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;NOS2 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;NOS2;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;IDO1;CYP1A1;NOS2 18226:[DB14011 DB02779] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways GO:0042593| glucose homeostasis PPARG;TRPV4;PTPN11;CNR1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;PTPN11 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;PTPN11;ALOX15 GO:0033629| negative regulation of cell adhesion mediated by integrin PTPN11;CYP1B1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PTPN11 GO:0006641| triglyceride metabolic process PTPN11;CAT;GPX1 GO:0007420| brain development ACAT1;PTPN11 GO:0040014| regulation of multicellular organism growth SOD1;PTPN11 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PTPN11;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2;PTPN11 GO:0007507| heart development PPARG;PTPN11 18227:[DB14011 DB08555] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08555|1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline MAPK10 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;MAPK10 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;MAPK10 GO:0048511| rhythmic process AANAT;MAPK10;PPARG GO:0009416| response to light stimulus MAPK10;AANAT GO:0042752| regulation of circadian rhythm PPARG;MAPK10 GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;MAPK10;CACNA1I;PLA2G1B 18228:[DB14011 DB08495] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08495|4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 18229:[DB14011 DB05303] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0050796| regulation of insulin secretion TNF;CNR1 GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;TNF GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;IL1R1;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0006919| activation of caspase activity TNF;PPARG GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0007166| cell surface receptor linked signaling pathway TRPA1;IL1R1;TRPV1 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation CNR1;PTGS2;TNF GO:0050727| regulation of inflammatory response IL1R1;TNF;PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;TNF;PPARG;PTGS2;CNR1;SOD1 GO:0010629| negative regulation of gene expression TNF;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;TNF;CAT GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;TNF;PTGS1;ALOX5;PTGS2;CNR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0006955| immune response OPRD1;CNR2;IL1R1;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TNF;OPRM1;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;TNF;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;TNF GO:0010628| positive regulation of gene expression TNF;TRPV4 GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TNF;TRPA1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0042127| regulation of cell proliferation PTGS2;PTGS1;TNF GO:0071230| cellular response to amino acid stimulus TNF;GLRA1 GO:0046330| positive regulation of JNK cascade TRPV4;TNF GO:0009615| response to virus CYP1A1;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;TNF;PPARG GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;TNF GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF 18230:[DB14011 DB07171] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways GO:0007507| heart development ECE1;PPARG 18231:[DB14011 DB00002] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication EGFR;PLA2G1B GO:0071276| cellular response to cadmium ion EGFR;CYP1A2;SOD1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;EGFR;PPARG;CYP1A1;TRPA1 GO:0008283| cell proliferation CYP1A1;EGFR;HTR1A;GPX1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;FCGR2B;EGFR;PLA2G1B;CACNA1I;FCGR1A;FCGR2C;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2;OPRD1 GO:0045907| positive regulation of vasoconstriction EGFR;HTR2A;PTGS2 GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0016032| viral reproduction FCGR2B;VDAC1;HTR2A GO:0006955| immune response FCGR1A;C1R;FCGR2B;FCGR3B;OPRD1;FCGR2C;FCGR3A;CNR2;C1QC GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;FCGR2B;TRPV1;ALOX15;IDO1 GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7 GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification EGFR;ALOX15 GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0001889| liver development ACAT1;CYP1A1;EGFR GO:0051592| response to calcium ion EGFR;AANAT GO:0007166| cell surface receptor linked signaling pathway EGFR;TRPV1;TRPA1 GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A GO:0007202| activation of phospholipase C activity EGFR;GPR55;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;EGFR;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0033993| response to lipid EGFR;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;EGFR GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;EGFR GO:0002376| immune system process C1R;C1QB;IDO1;FCGR2A;FCGR1A;C1QC;C1S;C1QA GO:0071363| cellular response to growth factor stimulus EGFR;TRPV1;CAT;OPRD1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;HMGCR;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;FCGR2A;FCGR3B GO:0045087| innate immune response C1R;C1QB;PPARG;FCGR1A;C1S;C1QC;C1QA GO:0043066| negative regulation of apoptotic process EGFR;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation EGFR;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0030324| lung development CYP1A2;EGFR GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0042127| regulation of cell proliferation EGFR;PTGS1;PTGS2 GO:0042060| wound healing EGFR;ALOX15;OPRM1 GO:0007623| circadian rhythm EGFR;AANAT 18232:[DB14011 DB03950] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03950|(S)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CA2;PTGS2;CYP1A2;SOD1 GO:0001822| kidney development CAT;CA2 18233:[DB14011 DB09146] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09146|Iron saccharate HBA1;TF common genes common pathways GO:0098869| HBA1;GSR;PTGS2;GPX1;PTGS1;CAT GO:0042744| hydrogen peroxide catabolic process HBA1;CAT;GPX1 GO:0002576| platelet degranulation SOD1;TF GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1H;TF;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0001895| retina homeostasis SOD1;TF GO:0051291| protein heterooligomerization GLRB;GLRA1;HBA1 GO:0042542| response to hydrogen peroxide HBA1;TRPA1;GPX1;CAT;SOD1 GO:0010942| positive regulation of cell death PTGS2;HBA1 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;TF 18234:[DB14011 DB09449] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0046686| response to cadmium ion SLC34A1;CAT GO:0055085| transmembrane transport SLC20A1;CACNA1H;TRPV3;SLC20A2;SLC34A3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;SLC34A2 GO:0051260| protein homooligomerization GLRA1;GLRA3;SLC34A1;ACAT1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;SLC34A1;CAT GO:0006810| transport SLC20A1;TRPV2;SLC20A2;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0033189| response to vitamin A SLC34A1;CAT;CYP1A1;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;SLC34A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0001822| kidney development CAT;SLC34A1 GO:0010288| response to lead ion CAT;SLC34A1 GO:0007584| response to nutrient SLC34A1;HMGCR;CNR1;PPARG GO:0043627| response to estrogen stimulus PPARG;SLC34A2 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;SLC20A1;SLC34A1;SLC34A3;TRPV2;CHRNA7;SLC20A2;CACNA1G;GLRA1;TRPA1;SLC34A2;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8 GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;SLC20A1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0043434| response to peptide hormone stimulus SLC34A1;TRPV1 GO:0046718| entry of virus into host cell SLC20A2;HTR2A GO:0016032| viral reproduction SLC20A2;HTR2A;VDAC1 GO:0001503| ossification SLC34A1;ALOX15 GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;SLC34A2;CACNA1H;SLC20A1;SLC34A3;SLC34A1;SLC20A2 18235:[DB14011 DB01964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01964|AL5424 CA2 common genes common pathways GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 18236:[DB14011 DB05428] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05428|motexafin gadolinium TXNRD1;TXNRD2;RRM2 common genes common pathways GO:0015949| nucleobase-containing small molecule interconversion GSR;RRM2;TXNRD1 GO:0008283| cell proliferation CYP1A1;HTR1A;TXNRD1;GPX1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;TXNRD1;CHRNA7 GO:0045454| cell redox homeostasis GSR;GPX1;TXNRD1;TXNRD2 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;TXNRD1;PPARG;CYP1A1 GO:0055114| oxidation-reduction process CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;RRM2;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1;TXNRD1;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;TXNRD2;CYP3A4 GO:0022900| electron transport chain GSR;IDO1;CYP1A2;TXNRD2;TXNRD1 GO:0034599| cellular response to oxidative stress TXNRD1;GPX1;CAT;SOD1;TXNRD2;GSR GO:0098869| GSR;TXNRD1;PTGS1;GPX1;CAT;PTGS2;TXNRD2 18237:[DB14011 DB07049] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07049|(2R)-1-[(4-tert-butylphenyl)sulfonyl]-2-methyl-4-(4-nitrophenyl)piperazine HSD11B1 common genes common pathways GO:0006704| glucocorticoid biosynthetic process HSD11B1;CYP17A1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;HMGCR;CYP1A2;CYP3A7;CYP3A4;HSD11B1 GO:0030324| lung development HSD11B1;CYP1A2 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;HSD11B1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;HSD11B1;NAAA;PTGS1;GPX1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B 18238:[DB14011 DB08787] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08787|4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine HSP90AA1 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;HSP90AA1;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;HSP90AA1 GO:0009409| response to cold TRPM8;HSP90AA1;PPARG;TRPA1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AA1;TRPV1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 18239:[DB14011 DB02201] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 18240:[DB14011 DB13269] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;SCN4A;TRPV1;SCN3A;SCN11A;SCN8A;GLRA3;CHRNA7;SCN1A;SCN7A GO:0055085| transmembrane transport TRPV2;SCN5A;SCN7A;SCN1A;CACNA1H;TRPV3;SCN9A;SCN8A;SCN11A;TRPV1;SCN4A;TRPV4;CACNA1I;VDAC1;ABCG2;SCN2A;TRPM8;SCN3A;CACNA1G;SCN10A;ABCC1;TRPA1 GO:0086002| SCN5A;SCN1A;CACNA1G;SCN1B;SCN3B;SCN4B;SCN2B GO:0006936| muscle contraction CACNA1H;SCN7A;GLRA1;SCN4A GO:0042391| regulation of membrane potential SCN1A;CACNA1H;GLRB;CACNA1G;GLRA1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;CAT;PTGS2;CYP1A2;SCN11A;HTR2A;SOD1 GO:0050884| neuromuscular process controlling posture SCN1A;GLRA1 GO:0086015| SCN3B;CACNA1G;SCN5A GO:0007628| adult walking behavior GLRA1;GLRB;SCN1A GO:0007155| cell adhesion CYP1B1;SCN1B GO:0001508| regulation of action potential SCN1A;CACNA1G;GLRA1 GO:0086016| SCN5A;SCN4B;CACNA1G;SCN10A GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN3B;SCN2B;SCN10A;SCN1B;CACNA1G;SCN5A GO:0009791| post-embryonic development SCN9A;CYP1A2 GO:0086046| SCN5A;CACNA1G GO:0009636| response to toxin CAT;GPX1;SCN9A;CYP1B1;CYP1A1 GO:0006811| ion transport SCN7A;SCN5A;SCN1A;CHRNA7;TRPV2;GLRA3;CACNA1H;SCN8A;SCN11A;SCN9A;TRPV3;SCN2A;SCN2B;SCN4B;SCN3A;TRPM8;SCN3B;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;SCN4A;GLRA1;TRPA1;SCN10A;SCN1B;CACNA1G GO:0051930| regulation of sensory perception of pain OPRD1;SCN11A;OPRM1 GO:0086045| SCN5A;CACNA1G GO:0034765| regulation of ion transmembrane transport CACNA1H;SCN8A;SCN11A;SCN9A;SCN7A;SCN5A;SCN1A;SCN10A;SCN1B;CACNA1G;CACNA1I;SCN4A;SCN2A;SCN2B;SCN4B;SCN3A;SCN3B GO:0010976| positive regulation of neuron projection development SCN1B;CNR1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;SCN9A;ALOX15;IDO1;TRPV1 GO:0007600| sensory perception TRPV2;OPRM1;SCN10A GO:0086010| SCN5A;SCN7A;SCN1A;CACNA1H;SCN9A;SCN11A;SCN8A;SCN4A;CACNA1I;SCN2A;SCN3B;SCN3A;CACNA1G;SCN10A GO:0050966| detection of mechanical stimulus involved in sensory perception of pain SCN1A;HTR2A;TRPA1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;GLRB;VDAC1;SCN2B;SCN1B;CACNA1G;GLRA1 GO:0002027| regulation of heart rate SCN5A;CACNA1G;SCN10A GO:0007399| nervous system development SCN8A;SMPD1;SCN2B;SCN3B;SCN2A;GLRB GO:0048266| behavioral response to pain SCN9A;TRPV1 GO:0086091| SCN5A;CACNA1G;SCN1B;SCN4B;SCN2B;SCN3B GO:0035725| sodium ion transmembrane transport SCN2A;SCN3B;SCN3A;SCN4B;SCN2B;SCN4A;CACNA1I;CACNA1G;SCN10A;SCN1B;SCN5A;SCN7A;SCN1A;CACNA1H;SCN9A;SCN8A;SCN11A GO:0019228| regulation of action potential in neuron SCN7A;SCN5A;SCN1A;CACNA1H;SCN8A;SCN11A;SCN9A;SCN2A;SCN3A;CACNA1I;SCN4A;SCN10A;CACNA1G GO:0019233| sensory perception of pain SCN9A;OPRD1;PTGS2;CNR2;OPRM1;CNR1;HTR2A;SCN10A;TRPA1;TRPV1;SCN3B GO:0071277| cellular response to calcium ion ALOX15;SCN5A 18241:[DB14011 DB07146] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways GO:0030217| T cell differentiation LCK;GPR18 GO:0016032| viral reproduction VDAC1;LCK;HTR2A GO:0006919| activation of caspase activity LCK;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;LCK GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;LCK;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0045087| innate immune response PPARG;LCK GO:0042127| regulation of cell proliferation LCK;PTGS2;PTGS1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;LCK;TRPV1;HTR2A 18242:[DB14011 DB07975] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0007565| female pregnancy DHODH;IDO1 GO:0007595| lactation DHODH;SLC29A1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;DHODH;SOD1;CNR1;PTGS2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;DHODH;AANAT;ACAT1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9;ALOX5;GPX1;PTGS1;DHODH;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT;DHODH GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0031000| response to caffeine PPARG;DHODH 18243:[DB14011 DB04739] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04739|4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE SRC common genes common pathways GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;SRC;CAT GO:0016236| macroautophagy VDAC1;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response SRC;PPARG GO:0009615| response to virus CYP1A1;SRC GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;SRC;CHRNA7;TRPV4;ALOX15 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process IDO1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0031667| response to nutrient levels SRC;SOD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2;SRC GO:0042542| response to hydrogen peroxide TRPA1;GPX1;SRC;CAT;SOD1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0008283| cell proliferation HTR1A;SRC;GPX1;CYP1A1 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0007165| signal transduction SRC;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption SRC;GPR55 18244:[DB14011 DB13775] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13775|Tertatolol CYP2D6 common genes CYP2D6 common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0051100| negative regulation of binding CYP2D6 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;ALOX15;CYP2D6;DAGLA;CYP1B1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 18245:[DB14011 DB08213] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways GO:0043200| response to amino acid stimulus CASP3;GLRA3;GLRB GO:0006915| apoptotic process VDAC1;GPX1;CASP3 GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;CASP3 GO:0010033| response to organic substance CASP3;CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;CASP3 GO:0009611| response to wounding CASP3;GPX1;CYP1A1 GO:0007605| sensory perception of sound SOD1;GPX1;CASP3 GO:0071407| cellular response to organic cyclic compound CASP3;CYP1B1;CYP1A1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT;CASP3 GO:0035094| response to nicotine CHRNA7;CASP3;CNR1 GO:0007611| learning or memory CNR1;CASP3;CHRNA7 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;CASP3;CYP1A1;IDO1 GO:0042060| wound healing OPRM1;CASP3;ALOX15 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;CASP3;GPX1 GO:0046677| response to antibiotic CYP1A1;CASP3;SOD1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;CASP3;ACAT1;AANAT GO:0009411| response to UV CASP3;CAT GO:0006919| activation of caspase activity CASP3;PPARG GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0035556| intracellular signal transduction CASP3;PLA2G1B GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;CASP3;GPX1 GO:0043065| positive regulation of apoptotic process CASP3;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0045165| cell fate commitment CASP3;PPARG GO:0007507| heart development CASP3;PPARG 18246:[DB14011 DB03555] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03555|CRA_11092 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18247:[DB14011 DB02034] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02034|Tridolgosir MAN2A1 common genes common pathways GO:0008152| metabolic process MAN2A1;SMPD1;ACAT1 GO:0001889| liver development ACAT1;MAN2A1;CYP1A1 GO:0050769| positive regulation of neurogenesis OPRM1;MAN2A1 18248:[DB14011 DB02986] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02986|N-(2-Thienylmethyl)-2,5-Thiophenedisulfonamide CA2 common genes common pathways GO:0010033| response to organic substance CA2;PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0001822| kidney development CAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 18249:[DB14011 DB03693] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;CSNK1G2;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 18250:[DB14011 DB05041] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05041|RP101 UPP1;UPP2 common genes common pathways GO:0006139| nucleobase-containing compound metabolic process UPP1;SLC29A1 18251:[DB14011 DB02624] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02624|Homoserine Lactone SLC9A1 common genes common pathways GO:0071456| cellular response to hypoxia SLC29A1;SLC9A1;OPRD1;PTGS2 GO:0071468| cellular response to acidity TRPV1;SLC9A1 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;CACNA1H;TRPV3;SLC9A1;TRPV2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;SLC9A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;PPARG;PLA2G1B GO:0071407| cellular response to organic cyclic compound SLC9A1;CYP1B1;CYP1A1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;SLC9A1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;SLC9A1;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0051930| regulation of sensory perception of pain SLC9A1;OPRD1;OPRM1 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;GLRA3;TRPV3;CACNA1H;SLC9A1;CHRNA7;TRPV2 GO:0006812| cation transport SLC9A1;TRPM8 GO:0071260| cellular response to mechanical stimulus SLC9A1;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2;SLC9A1 18252:[DB14011 DB08595] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08595|4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0048511| rhythmic process AANAT;NCOA2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NCOA2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;NCOA2;TRPV4;TRPV1 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0007165| signal transduction CHRNA7;ESR1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;NCOA2;CNR1;HMGCR GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG 18253:[DB14011 DB11348] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes CACNA1H;CACNA1I;CACNA1G common pathways GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;CASR GO:0016525| negative regulation of angiogenesis SPARC;PPARG GO:0033189| response to vitamin A CAT;SLC34A1;PPARG;CYP1A1 GO:0007517| muscle organ development SRI;CACNA1H GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;CALR;SMPD1;ABCC1;CAT;SLC34A1;SLC8A1;SOD1;HTR2A;CYP1A2;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0032342| aldosterone biosynthetic process CACNA1H GO:0042311| vasodilation GPX1;CASR GO:0001822| kidney development RGN;SLC34A1;CAT;PKD1L3 GO:0086015| CACNA1G GO:0035722| interleukin-12-mediated signaling pathway SOD1;CANX GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;RGN;SOD1;TPT1;CIB1;ALB GO:0002576| platelet degranulation SPARC;CALM1;SOD1;ALB GO:0070207| protein homotrimerization TRPM8;PKD2L1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;CASR;S100A13;S100B;CALR;CIB1 GO:0007626| locomotory behavior SOD1;OPRM1;CALB1 GO:0010045| response to nickel cation CACNA1G GO:0009615| response to virus CYP1A1;TPT1 GO:0010288| response to lead ion SPARC;CAT;SLC34A1 GO:0043312| neutrophil degranulation CAT;ALOX5;GCA GO:0035902| response to immobilization stress PPARG;CYP1A1;SLC8A1;CYP1A2 GO:0035307| positive regulation of protein dephosphorylation CALM3;CALM1;SMPD1;CALM2 GO:0045087| innate immune response S100B;PPARG GO:0007155| cell adhesion CIB1;CYP1B1;NRXN1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;PPARG;TRPV1;TRPV4 GO:0034097| response to cytokine stimulus PTGS2;AANAT;SPARC GO:0007611| learning or memory CNR1;S100B;CHRNA7;CALB1 GO:0071318| cellular response to ATP TRPV1;CIB2;RYR3;PTGS2;SOD1 GO:0042127| regulation of cell proliferation CIB1;PTGS2;SPARC;PTGS1 GO:0042060| wound healing ALOX15;SPARC;OPRM1 GO:0007612| learning VDAC1;PTGS2;NRXN1 GO:0001508| regulation of action potential SRI;GLRA1;CACNA1G GO:0032496| response to lipopolysaccharide SPARC;CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;CYP1A1 GO:0051481| reduction of cytosolic calcium ion concentration RYR3;OPRM1;SLC8A1 GO:0070509| calcium ion import SLC8A1;CACNA1D;CASR;CACNA1H;CACNB2;TRPV4;CACNA1I;CACNA1G GO:0007269| neurotransmitter secretion NRXN1;NAAA GO:0030317| sperm motility CATSPER1;CACNA1I GO:0071333| cellular response to glucose stimulus CASR;SLC29A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;CASR GO:0030324| lung development SPARC;CYP1A2 GO:0086016| CACNA1G GO:0007614| short-term memory CHRNA7;CALB1 GO:0046688| response to copper ion SOD1;S100A13;AANAT GO:0010628| positive regulation of gene expression CASR;TRPV4;CALR GO:0010977| negative regulation of neuron projection development CIB1;TRPV4 GO:0001666| response to hypoxia CYP1A1;RYR2;RYR1;SLC8A1;CHRNA7;CAT GO:0007283| spermatogenesis CALR;CATSPER1;CIB1;CNR1;SOD1;RGN;CALR3 GO:0051968| positive regulation of synaptic transmission, glutamatergic NRXN1;PTGS2 GO:0010033| response to organic substance SOD1;CASQ1;PTGS2;CYP1A2;TRPA1;CALR;PPARG;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CALR GO:0051262| protein tetramerization CAT;HMGCR;TRPV5 GO:0031000| response to caffeine RYR2;PPARG;RYR1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential NRXN1;CHRNA7 GO:0048741| skeletal muscle fiber development RYR1;GPX1 GO:0071356| cellular response to tumor necrosis factor CIB1;TRPV1 GO:0034220| ion transmembrane transport CASQ2;RYR2;TRPV1;GLRB;TRPA1;GLRA1;RYR3;CHRNA7;S100A6;RYR1;GLRA3;CASQ1 GO:0051591| response to cAMP SPARC;AANAT GO:0046686| response to cadmium ion SLC34A1;SPARC;CAT GO:0006915| apoptotic process VDAC1;PDCD6;CIB1;GPX1;CASR GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;PDCD6 GO:0008219| cell death CACNA1A;HTR2A GO:0055085| transmembrane transport RYR2;CACNA1F;SLC34A2;CACNA1A;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;RYR3;ABCC1;CACNA1E;CACNA1G;TRPV5;CATSPER1;CACNA1S;TRPA1;TRPV6;RYR1;CACNA1C;SLC8A1;CACNA1D;SLC34A3;TRPV2;SLC20A2;CALM1;TRPV3;CACNA1H;SLC20A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;CIB1;TRPV4;ALOX15 GO:0086002| CACNA1G;CACNA1D;CACNA1C GO:0006936| muscle contraction RYR1;SLC8A1;CALM1;CACNA1H;CACNA1S;GLRA1 GO:0006874| cellular calcium ion homeostasis RGN;TPT1;GPR12;HTR2A;CASR;CHRNA7;SLC8A1;RYR1;CALR;RYR3;TRPM8;TRPV4;RYR2 GO:0098869| PTGS2;GPX1;PTGS1;CAT;ALB;GSR GO:1901214| CHP1;CHRNA7 GO:0042391| regulation of membrane potential CACNA1H;GLRB;GLRA1;CACNA1G GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC34A1;GLRA1 GO:0007605| sensory perception of sound SOD1;CACNA1D;GPX1 GO:0043085| positive regulation of catalytic activity SOD1;CIB1 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1;PDCD6 GO:0051209| release of sequestered calcium ion into cytosol RYR1;HTR2A;TRPV1;RYR2;TRPA1;RYR3 GO:0071468| cellular response to acidity PKD1L3;PKD2L1;CHP1;TRPV1 GO:0032355| response to estradiol stimulus CALR;CAT;SLC34A1;PTGS2;CYP1A2 GO:0086018| CACNA1G GO:0086027| CACNA1G GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CASR;CALM1;CALM3;PPARG;GPR18;CALM2 GO:0071363| cellular response to growth factor stimulus OPRD1;SPARC;CAT;TRPV1;CIB1 GO:0007568| aging CANX;CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;RGN;CNR1;SOD1;HTR2A GO:0007635| chemosensory behavior TRPV1;CASR GO:0006810| transport CACNB4;TRPV2;SLC20A2;SRI;SLC20A1;TRPV1;CACNA1I;ABCG2;CACNB1;CACNA1E;ABCC1;CACNB3 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;S100B;SLC8A1;CASR GO:0006816| calcium ion transport TRPV1;CACNA1I;TRPV4;CACNA1A;CACNA1F;RYR2;CACNB1;TRPM8;TRPV5;CACNA1S;CATSPER1;PKD2L1;CACNA1G;CACNA1E;RYR3;TRPV6;TRPA1;CACNB3;TRPV2;CACNB4;SLC8A1;CACNA1D;CACNA1C;RYR1;CASR;CHRNA7;PKD1L3;CACNA1H;TRPV3;SRI;CACNB2;TPT1 GO:0016032| viral reproduction SLC20A2;HTR2A;VDAC1 GO:0009408| response to heat TRPV3;CASQ1;SOD1;TRPV2;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CIB1;CAT GO:0051289| protein homotetramerization TRPM8;TRPV1;CRYZ;TRPA1;RYR3;CAT;RYR1 GO:0034651| cortisol biosynthetic process CACNA1H GO:0086010| CACNA1H;CACNA1F;CACNA1A;CACNA1I;CACNA1E;CACNA1G;CATSPER1;CACNA1S GO:0051924| regulation of calcium ion transport CASR;SLC8A1;SRI;OPRD1 GO:0007268| synaptic transmission CACNA1E;CACNA1G;GLRA1;CACNB3;GLRB;VDAC1;CACNB1;OPRD1;NRXN1;OPRM1;HTR2A;GLRA3;CACNB2;CACNB4 GO:0098703| TRPV5;TRPV6;TRPV1 GO:0071320| cellular response to cAMP SLC8A1;AANAT GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis CIB1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CIB1;CHRNA7 GO:0035556| intracellular signal transduction CAPS;PLA2G1B GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;S100B;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CACNA1D GO:0042542| response to hydrogen peroxide CAT;GPX1;SLC8A1;SOD1;TRPA1 GO:0060078| regulation of postsynaptic membrane potential SLC8A1;CHRNA7 GO:1990090| CIB1;TRPV1 GO:0001503| ossification CASR;SPARC;SLC34A1;ALOX15 GO:0007507| heart development CACNA1C;SPARC;SRI;PPARG GO:0002027| regulation of heart rate CASQ2;RYR2;CALM2;CACNA1G;CALM1;CALM3;SLC8A1 GO:0086091| CACNA1G;CACNA1D;CACNA1C;CACNB2 GO:0008016| regulation of heart contraction CACNA1H;SRI GO:0035725| sodium ion transmembrane transport SLC20A1;CACNA1H;SLC20A2;SLC34A1;SLC8A1;SLC34A3;PKD2L1;CACNA1G;SLC34A2;CACNA1I GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1I;CACNA1G GO:0051592| response to calcium ion PDCD6;TRPV6;CALM2;S100A16;SPARC;CALM1;CASR;CALM3;AANAT;PEF1 GO:0001889| liver development CYP1A1;RGN;ACAT1 GO:0045471| response to ethanol SPARC;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0001525| angiogenesis PDCD6;CIB1;CYP1B1;PTGS2 GO:0098662| CACNA1H GO:0071277| cellular response to calcium ion RYR3;ALOX15;RYR1 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G GO:0048146| positive regulation of fibroblast proliferation S100A6;PLA2G1B GO:0045740| positive regulation of DNA replication CALR;PLA2G1B GO:0050896| response to stimulus TRPM8;CACNA1F;TRPA1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CIB1;CYP1B1 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0043627| response to estrogen stimulus SLC34A2;PPARG GO:0090280| positive regulation of calcium ion import TRPV3;TRPV2;CASR GO:0086046| CACNA1G;CACNA1D GO:0007584| response to nutrient PPARG;HMGCR;CNR1;SLC8A1;SLC34A1 GO:0006812| cation transport PKD1L3;PKD2L1;TRPM8 GO:0006919| activation of caspase activity PDCD6;PPARG GO:0014070| response to organic cyclic compound ACAT1;AANAT;CASR;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0043267| negative regulation of potassium ion transport HTR2A;CASQ2 GO:0006811| ion transport TRPV1;CACNA1A;CACNA1I;TRPV4;GLRB;VDAC1;CACNA1F;SLC34A2;RYR2;CACNB1;TRPM8;PKD2L1;CACNA1G;TRPV5;CATSPER1;CACNA1S;CACNA1E;RYR3;TRPV6;TRPA1;GLRA1;CACNB3;CACNB4;SLC34A3;TRPV2;SLC8A1;CACNA1D;SLC34A1;CACNA1C;RYR1;CHRNA7;SLC20A2;PKD1L3;CACNA1H;TRPV3;SLC20A1;CACNB2;GLRA3 GO:0086045| CACNA1G;CACNB2;CACNA1C GO:0008283| cell proliferation HTR1A;GPX1;S100B;CYP1A1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CHP1;CYP1B1 GO:0001895| retina homeostasis SOD1;ALB GO:0033591| response to L-ascorbic acid SPARC;CAT GO:0032870| cellular response to hormone stimulus CACNA1H GO:1904645| CACNA1A;CHRNA7 GO:0045907| positive regulation of vasoconstriction CASR;HTR2A;PTGS2 GO:0043010| camera-type eye development FBN2;CACNA1C;CYP1A1 GO:0034765| regulation of ion transmembrane transport CACNB1;CACNA1A;CACNA1I;CACNA1F;CACNB3;CACNA1G;CATSPER1;CACNA1S;CACNA1E;CACNA1D;CACNB4;CACNA1C;CACNB2;CACNA1H GO:0070588| calcium ion transmembrane transport CACNB2;TRPV3;OPRM1;CACNA1H;PKD1L3;CHRNA7;RYR1;NCS1;CACNA1C;CACNA1D;SLC8A1;CACNB4;TRPV2;CACNB3;TRPA1;TRPV6;RYR3;CACNA1E;CACNA1G;PKD2L1;CATSPER1;CACNA1S;TRPV5;TRPM8;CACNB1;RYR2;CACNA1F;CACNA1A;CACNA1I;TRPV4;TRPV1 GO:0065009| regulation of molecular function TRPV1;NRXN1 GO:0045019| negative regulation of nitric oxide biosynthetic process RGN;OPRM1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;SRI;GPR55;SLC20A1;HTR1A;CNR1;GPR12;HTR2A;SPARC;CASR;CHRNA7;S100A6 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CACNA1I;CACNA1G GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0046718| entry of virus into host cell SLC20A2;HTR2A GO:0043434| response to peptide hormone stimulus TRPV1;SPARC;SLC34A1 GO:0051384| response to glucocorticoid stimulus PTGS2;S100B;SPARC GO:0007601| visual perception CACNB2;GLRA1;CRYZ;GLRB;CYP1B1;CACNA1F GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway CASR;OPRM1;OPRD1 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7;S100B GO:0007520| myoblast fusion CACNA1H GO:0007204| elevation of cytosolic calcium ion concentration CIB2;TRPV1;CACNA1A;TRPV4;HTR2A;OPRM1;CACNA1C;SLC8A1 GO:0050796| regulation of insulin secretion CACNA1E;CACNA1A;CNR1;CACNA1D;CACNA1C 18254:[DB14011 DB08230] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08230|5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE PIM1 common genes common pathways GO:0008283| cell proliferation CYP1A1;HTR1A;PIM1;GPX1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;PIM1;CAT;GPX1 GO:0006915| apoptotic process PIM1;GPX1;VDAC1 18255:[DB14011 DB07644] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07644|5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine DCPS common genes common pathways 18256:[DB14011 DB12191] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12191|Obatoclax BCL2 common genes common pathways GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0034097| response to cytokine stimulus PTGS2;BCL2;AANAT GO:0001822| kidney development BCL2;CAT GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;BCL2;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation PTGS2;BCL2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0007569| cell aging BCL2;SOD1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;BCL2;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0007015| actin filament organization TRPV4;PLA2G1B;BCL2 GO:0035094| response to nicotine BCL2;CNR1;CHRNA7 GO:0071456| cellular response to hypoxia SLC29A1;BCL2;OPRD1;PTGS2 GO:0010468| regulation of gene expression BCL2;CYP1A2 GO:0043085| positive regulation of catalytic activity BCL2;SOD1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;BCL2;PTGS2;SOD1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;GPR12;HTR2A;BCL2 GO:0048538| thymus development SOD1;BCL2 GO:0006915| apoptotic process VDAC1;GPX1;BCL2 GO:0001541| ovarian follicle development SOD1;BCL2 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;BCL2;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0001657| ureteric bud development CAT;BCL2 GO:0001503| ossification ALOX15;BCL2 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;BCL2;CAT;GPX1 GO:0009314| response to radiation CAT;BCL2;PTGS2;OPRM1 GO:0007565| female pregnancy IDO1;BCL2 GO:0008631| induction of apoptosis by oxidative stress BCL2;GPX1;CYP1B1 GO:0043524| negative regulation of neuron apoptosis BCL2;SOD1 GO:0051924| regulation of calcium ion transport OPRD1;BCL2 GO:0030217| T cell differentiation BCL2;GPR18 GO:0072593| reactive oxygen species metabolic process BCL2;SOD1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCL2 GO:0010332| response to gamma radiation GPX1;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BCL2;PTGS2 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;BCL2 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;BCL2 GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;VDAC1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;BCL2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;BCL2;CYP1B1;PPARG GO:0001662| behavioral fear response VDAC1;BCL2;HTR1A GO:0030336| negative regulation of cell migration CYP1B1;BCL2 GO:0009791| post-embryonic development BCL2;CYP1A2 18257:[DB14011 DB03039] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03039|4-(Aminosulfonyl)-N-[(2,5-Difluorophenyl)Methyl]-Benzamide CA2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CA2;TRPA1;PPARG;CYP1A1 GO:0001822| kidney development CAT;CA2 18258:[DB14011 DB04352] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 18259:[DB14011 DB03626] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03626|5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;NQO1;CYP2C9;CYP1A1;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;NQO1 GO:0007568| aging CYP1A1;NQO1;CAT;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;NQO1 GO:0019430| removal of superoxide radicals SOD1;NQO1 GO:0045471| response to ethanol NQO1;CAT;OPRM1;HMGCR;SOD1;CNR1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;NQO1;CYP2C9 GO:0009636| response to toxin NQO1;CYP1A1;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound TRPA1;NQO1;CYP1A1;PPARG;AANAT;ACAT1;PTGS2;CYP1A2 GO:0006809| nitric oxide biosynthetic process CYP1B1;NQO1 GO:0007584| response to nutrient CNR1;HMGCR;NQO1;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1;NQO1 18260:[DB14011 DB03727] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03727|Coproporphyrin I UROD common genes common pathways 18261:[DB14011 DB08807] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes HTR1A;CYP2D6 common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1;HTR1B;ADRB3 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0014059| regulation of dopamine secretion HTR1B;HTR2A GO:0042220| response to cocaine HTR1B;SMPD1;OPRM1;CNR1 GO:0014062| regulation of serotonin secretion HTR1A GO:0071502| cellular response to temperature stimulus HTR1B;TRPV1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0007210| serotonin receptor signaling pathway HTR2A;HTR1A GO:0007568| aging ADRB3;CYP1A1;CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;ADRB2;HTR1A;GPR55;HTR1B;ADRB1;ADRB3;GPR18;PPARG GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0035640| exploration behavior HTR1A GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;HTR1B GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;DAGLA;CYP2D6;FAAH GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;HTR1B;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0050795| regulation of behavior HTR1B;HTR2A;HTR1A GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ADRB2 GO:0046677| response to antibiotic SOD1;CYP1A1;ADRB3 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0002024| diet induced thermogenesis ADRB2;ADRB3;TRPV1;TRPV4;ADRB1 GO:0001662| behavioral fear response HTR1A;VDAC1 GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0042053| regulation of dopamine metabolic process HTR1A GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0032229| negative regulation of synaptic transmission, GABAergic HTR1B;CNR2 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1 GO:0042755| eating behavior OPRD1;OPRM1;ADRB3 GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A;HTR1B GO:0007610| behavior HTR1A;HTR2A;HTR1B GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;ADRB2;PLA2G1B;HTR1B;ADRB1;CACNA1I;ADRB3;SMPD1;PPARG;GPR18 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0045453| bone resorption ADRB2;GPR55 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;HTR1B GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;HTR1B;GLRB;VDAC1;GLRA1;CACNA1G GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG;GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB3;ADRB2;CNR1 GO:0001659| temperature homeostasis TRPV1;ADRB1;ADRB3;HTR2A;GPX1 GO:0071312| cellular response to alkaloid HTR1B;TRPV1 GO:0042428| serotonin metabolic process HTR1A GO:0009409| response to cold ADRB1;ADRB3;TRPM8;TRPA1;PPARG;ADRB2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0042310| vasoconstriction HTR1A;HTR1B GO:0050873| brown fat cell differentiation ADRB3;ADRB1;ADRB2;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;ADRB2 GO:0045471| response to ethanol HTR1B;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 18262:[DB14011 DB08406] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;DHFR;CRYZ;CYP1A1;CYP2C9 18263:[DB14011 DB05057] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05057|Erdosteine ADA common genes common pathways GO:0042542| response to hydrogen peroxide SOD1;CAT;ADA;GPX1;TRPA1 GO:0001889| liver development CYP1A1;ADA;ACAT1 GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0001890| placenta development ADA;SOD1;PPARG GO:0007155| cell adhesion CYP1B1;ADA GO:0043066| negative regulation of apoptotic process CAT;ADA;GPX1;SOD1;HMGCR;PTGS2 GO:0030324| lung development CYP1A2;ADA GO:0033197| response to vitamin E CAT;ADA GO:0043278| response to morphine CNR1;OPRM1;ADA GO:0050728| negative regulation of inflammatory response CNR2;ADA GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;ADA;CAT GO:0007568| aging CAT;ADA;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CYP1A1 GO:0001666| response to hypoxia ADA;CHRNA7;CAT;CYP1A1 18264:[DB14011 DB06734] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways GO:0034220| ion transmembrane transport ATP6V1A;CHRNA7;GLRA3;GLRB;TRPV1;TRPA1;GLRA1 GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;ATP6V1A GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;ATP6V1A;CHRNA7 GO:0006879| cellular iron ion homeostasis ATP6V1A;SOD1;ABCG2 18265:[DB14011 DB00578] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways GO:0019369| arachidonic acid metabolic process DAGLA;CYP2D6;ALOX15;CYP1B1;PLA2G4A;FAAH GO:0006654| phosphatidic acid biosynthetic process PLA2G4A;PLA2G1B GO:0036151| PLA2G4A;PLA2G1B GO:0042127| regulation of cell proliferation PLA2G4A;PTGS1;PTGS2 GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G4A;PLA2G1B GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0016042| lipid catabolic process PLA2G4A;DAGLA;PLA2G1B;NAPEPLD GO:0036152| PLA2G1B;PLA2G4A GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0051260| protein homooligomerization SLC22A6;GLRA1;GLRA3;ACAT1 GO:0006629| lipid metabolic process PLA2G4A;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0036148| PLA2G4A;PLA2G1B GO:0008152| metabolic process ACAT1;SMPD1;PLA2G4A GO:0036149| PLA2G1B;PLA2G4A GO:0036150| PLA2G1B;PLA2G4A GO:0098656| SLC22A6;VDAC1 GO:0009395| phospholipid catabolic process PLA2G4A;NAPEPLD GO:0050482| arachidonic acid secretion PLA2G4A;PLA2G1B 18266:[DB14011 DB07708] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07708|3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV4;TRPV1 GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;HMGCR;CNR1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;ESR1;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TRPV1;TRPV4;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NCOA2;PPARG;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0048511| rhythmic process AANAT;NCOA2;PPARG GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 18267:[DB14011 DB03006] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03006|Arsanilic acid LYZ common genes common pathways GO:0008152| metabolic process LYZ;SMPD1;ACAT1 GO:0006954| inflammatory response IDO1;ALOX15;LYZ;TRPV1;ALOX5;PTGS1;PTGS2;CNR2 GO:0001895| retina homeostasis SOD1;LYZ GO:0043312| neutrophil degranulation LYZ;ALOX5;CAT GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LYZ 18268:[DB14011 DB05483] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05483|PCL-016 UBR4;ZFY common genes common pathways GO:0007283| spermatogenesis SOD1;CNR1;ZFY GO:0001541| ovarian follicle development SOD1;ZFY GO:0043312| neutrophil degranulation UBR4;ALOX5;CAT GO:0006355| regulation of transcription, DNA-dependent ZFY;PPARG GO:0009791| post-embryonic development ZFY;CYP1A2 GO:0006351| transcription, DNA-dependent PPARG;ZFY GO:0016032| viral reproduction UBR4;HTR2A;VDAC1 18269:[DB14011 DB08461] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;TRPV2;AR GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;AR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV1;TRPV4 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;AR GO:0008285| negative regulation of cell proliferation AR;OPRM1;PTGS2;CYP1B1;PPARG GO:0008283| cell proliferation HTR1A;AR;GPX1;CYP1A1 GO:0007548| sex differentiation CYP17A1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B 18270:[DB14011 DB08751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways GO:0051291| protein heterooligomerization HRAS;GLRA1;GLRB GO:0045740| positive regulation of DNA replication HRAS;PLA2G1B GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;HRAS;PPARG;CYP1B1 GO:0008283| cell proliferation CYP1A1;HTR1A;HRAS;GPX1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;HRAS;GPR55;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;HRAS GO:0043524| negative regulation of neuron apoptosis HRAS;SOD1 GO:0001934| positive regulation of protein phosphorylation HRAS;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;HRAS GO:0010628| positive regulation of gene expression TRPV4;HRAS GO:0043406| positive regulation of MAP kinase activity HRAS;HTR2A GO:0006915| apoptotic process HRAS;GPX1;VDAC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;HRAS;CHRNA7;TRPV4;ALOX15 GO:0035900| response to isolation stress HRAS;NAPEPLD GO:0007569| cell aging HRAS;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;HRAS GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;HRAS GO:0046330| positive regulation of JNK cascade HRAS;TRPV4 18271:[DB14011 DB01153] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01153|Sertaconazole CYP51A1 common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process CYP51A1;HMGCR GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP51A1;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;CYP51A1;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;CYP51A1 GO:0008203| cholesterol metabolic process CYP51A1;HMGCR;CAT GO:0006695| cholesterol biosynthetic process CYP51A1;HMGCR GO:0070988| demethylation CYP1A1;CYP51A1 GO:0016125| sterol metabolic process CYP51A1;CYP17A1;CYP1B1 GO:0016126| sterol biosynthetic process HMGCR;CYP51A1 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;PTGS1;NAAA;GPX1;HMGCR;CYP51A1;PTGS2;CYP1A2;CYP3A4;NAPEPLD 18272:[DB14011 DB07172] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes PPARG common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;PPARG;CYP1A1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0015909| long-chain fatty acid transport PPARG 18273:[DB14011 DB09502] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0009750| response to fructose stimulus PTGS2;SLC2A5 GO:0043312| neutrophil degranulation SLC2A5;ALOX5;CAT;SLC2A3 GO:0055085| transmembrane transport CACNA1G;ABCC1;SLC2A4;TRPA1;SLC2A10;VDAC1;CACNA1I;TRPV4;TRPV1;SLC2A2;ABCG2;SLC2A5;TRPM8;CACNA1H;SLC2A1;SLC2A8;TRPV3;SLC2A9;SLC2A12;SLC2A3;TRPV2;SLC2A6;SLC2A7;SLC2A11 GO:0071356| cellular response to tumor necrosis factor SLC2A4;TRPV1 GO:0015758| glucose transport SLC2A8;SLC2A1;SLC2A12;SLC2A9;SLC2A3;PLA2G1B;SLC2A10;SLC2A2;SLC2A5;SLC2A4 GO:0071470| cellular response to osmotic stress SLC2A4;TRPV4 GO:0001666| response to hypoxia CAT;CHRNA7;SLC2A8;CYP1A1 GO:0071456| cellular response to hypoxia SLC2A4;SLC29A1;OPRD1;PTGS2 GO:0042593| glucose homeostasis TRPV4;SLC2A4;PPARG;CNR1 GO:0046415| urate metabolic process SLC2A9;ABCG2 GO:0007565| female pregnancy SLC2A1;IDO1 GO:0050873| brown fat cell differentiation SLC2A4;PTGS2 GO:0045471| response to ethanol SLC2A4;HMGCR;OPRM1;CNR1;SOD1;CAT GO:0006970| response to osmotic stress SLC2A1;TRPV4 GO:0071260| cellular response to mechanical stimulus SLC2A1;PTGS2 GO:0008152| metabolic process HK1;SMPD1;ACAT1 GO:0032868| response to insulin stimulus AANAT;CAT;SLC2A1;TRPV4 GO:0050796| regulation of insulin secretion SLC2A2;CNR1;SLC2A1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;SLC2A4 GO:0042908| xenobiotic transport SLC2A1;ABCG2;ABCC1 18274:[DB14011 DB01070] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01070|Dihydrotachysterol VDR common genes common pathways GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG GO:0006351| transcription, DNA-dependent VDR;PPARG GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G;CHRNA7;VDR;TRPV2;TRPV3;CACNA1H GO:0007595| lactation SLC29A1;VDR GO:0007165| signal transduction CHRNA7;VDR;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;VDR;PPARG;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;VDR GO:0006367| transcription initiation from RNA polymerase II promoter VDR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;VDR GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;VDR;HTR2A;GPR12 GO:0046697| decidualization VDR;PTGS2 GO:0010628| positive regulation of gene expression TRPV4;VDR GO:0045892| negative regulation of transcription, DNA-dependent PPARG;VDR 18275:[DB14011 DB04683] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;NR5A1 GO:0006367| transcription initiation from RNA polymerase II promoter NR5A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR5A1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR5A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR5A1 GO:0006351| transcription, DNA-dependent NR5A1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR5A1 GO:0006357| regulation of transcription from RNA polymerase II promoter NR5A1;PPARG 18276:[DB14011 DB05505] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05505|NM-702 TBXAS1 common genes common pathways GO:0019371| cyclooxygenase pathway TBXAS1;PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2;TBXAS1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;NAAA;PTGS1;GPX1;PPARG;CYP2C9;TBXAS1;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1;TBXAS1 GO:0006633| fatty acid biosynthetic process PLA2G1B;TBXAS1;PTGS2;PTGS1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;TBXAS1;ALOX15 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2C19;GSR;IDO1;TBXAS1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;GPX1;ALOX5;PTGS1 18277:[DB14011 DB02763] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways GO:0008283| cell proliferation GPX1;HTR1A;IL12B;CYP1A1 GO:0050729| positive regulation of inflammatory response TRPV4;IL12B GO:0048662| negative regulation of smooth muscle cell proliferation IL12B;PPARG GO:0032693| negative regulation of interleukin-10 production IDO1;IL12B GO:0019233| sensory perception of pain HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1;TRPA1;TRPV1;IL12B GO:0007166| cell surface receptor linked signaling pathway TRPA1;IL12B;TRPV1 GO:0010033| response to organic substance IL12B;TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0032735| positive regulation of interleukin-12 production IL12B;IDO1 GO:0002862| negative regulation of inflammatory response to antigenic stimulus IL12B;GPX1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;IL12B 18278:[DB14011 DB01240] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1;PTGIS GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;PTGIS;CYP1B1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGIS;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;P2RY12 GO:0007566| embryo implantation PTGS2;SOD1;PTGIS GO:0007165| signal transduction GPR18;PTGIR;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;P2RY12;CHRNA7 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGIS;PTGS1;PTGS2 GO:0065009| regulation of molecular function P2RY12;PTGIR;TRPV1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;PTGIS GO:0070588| calcium ion transmembrane transport CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1;TRPV2;P2RY12;CHRNA7;TRPV3;CACNA1H;OPRM1 GO:0048662| negative regulation of smooth muscle cell proliferation PTGIR;PPARG GO:0019371| cyclooxygenase pathway PTGIS;PTGS2;PTGS1 GO:0051924| regulation of calcium ion transport P2RY12;OPRD1 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;PTGIS;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger P2RY12;CNR1 GO:0006693| prostaglandin metabolic process PTGIS;PTGS2;PTGS1 GO:0045766| positive regulation of angiogenesis CHRNA7;PTGIS;CYP1B1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGIR;OPRD1;CNR2;OPRM1;CNR1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;PTGIS GO:0046697| decidualization PTGIS;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway P2RY12;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;PTGIR;GPR18;PPARG GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;PTGIS;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;PTGIS;ALOX15 GO:0071407| cellular response to organic cyclic compound P2RY12;CYP1B1;CYP1A1 GO:0050728| negative regulation of inflammatory response CNR2;PTGIS GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;PTGIR;CYP1A1 GO:0071318| cellular response to ATP P2RY12;SOD1;PTGS2;TRPV1 18279:[DB14011 DB08847] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08847|Hydroxyproline SLC36A1 common genes common pathways GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;SLC36A1;TRPV2;CHRNA7 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;CACNA1H;TRPV3;SLC36A1;TRPV2 18280:[DB14011 DB02383] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG;AKR1B1 GO:0008202| steroid metabolic process AKR1B10;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;AKR1B1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;AKR1B1;AKR1A1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;AKR1B10;AKR1A1;CRYZ;AKR1B1;CYP2C9;CYP1A1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0001523| retinoid metabolic process NAPEPLD;AKR1B10 18281:[DB14011 DB11607] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11607|Efmoroctocog alfa VWF common genes common pathways GO:0002576| platelet degranulation VWF;SOD1 GO:0007155| cell adhesion CYP1B1;VWF GO:0009611| response to wounding CYP1A1;VWF;GPX1 GO:0051260| protein homooligomerization GLRA1;GLRA3;VWF;ACAT1 18282:[DB14011 DB00152] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;CYP4B1;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP2C9;CYP1A1;CRYZ GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC22A5;TRPV2;ABCC1;SLC22A1;CACNA1G;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;SLC22A2;TRPM8;ABCG2 GO:0051260| protein homooligomerization GLRA1;SLC22A1;ACAT1;GLRA3 GO:0042738| exogenous drug catabolic process CYP1A2;CYP4B1;CYP3A4;CYP2C19;CYP2C9 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0006812| cation transport TRPM8;SLC22A2;SLC22A1 GO:0006725| cellular aromatic compound metabolic process CYP4B1;CYP1A2;CYP1B1 GO:0006855| drug transmembrane transport SLC22A1;ABCC1;SLC22A2;ABCG2;SLC22A5 GO:0006811| ion transport VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;SLC22A2;TRPM8;SLC22A1;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;SLC22A5;GLRA3 18283:[DB14011 DB04964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04964|Oregovomab MUC16 common genes common pathways GO:0007155| cell adhesion MUC16;CYP1B1 18284:[DB14011 DB07225] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07225|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE CTSB common genes common pathways GO:0046718| entry of virus into host cell CTSB;HTR2A GO:0043312| neutrophil degranulation ALOX5;CAT;CTSB GO:0030855| epithelial cell differentiation CTSB;VDAC1;PPARG GO:0046697| decidualization CTSB;PTGS2 18285:[DB14011 DB05476] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05476|WX-UK1 PLAUR common genes common pathways GO:0043312| neutrophil degranulation PLAUR;ALOX5;CAT GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;PLAUR GO:0043388| positive regulation of DNA binding PLAUR;PPARG GO:0001934| positive regulation of protein phosphorylation CHRNA7;PLAUR GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;PLAUR;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 18286:[DB14011 DB04727] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04727|N-(4-{4-AMINO-6-[4-(METHYLOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-5-YL}PHENYL)-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA KDR common genes common pathways GO:0001525| angiogenesis CYP1B1;KDR;PTGS2 GO:0016032| viral reproduction HTR2A;VDAC1;KDR GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;KDR GO:0043066| negative regulation of apoptotic process KDR;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;KDR;ALOX15 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;KDR 18287:[DB14011 DB00097] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LHCGR;HTR2A;OPRM1;OPRD1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FSHR GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;FSHR;CNR2;OPRM1;OPRD1;LHCGR;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;FSHR;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;LHCGR;OPRD1;CNR2;OPRM1 GO:0007283| spermatogenesis FSHR;CNR1;SOD1 GO:0050890| cognition CHRNA7;LHCGR GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;LHCGR;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;FSHR 18288:[DB14011 DB03971] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03971|Acarbose Derived Hexasaccharide AMY2A;AMY2A common genes common pathways GO:0008152| metabolic process SMPD1;AMY2A;ACAT1 18289:[DB14011 DB00210] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes PTGS2 common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;RARA GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0097756| HMGCR;PTGS2 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0007568| aging CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;RARA;GPR18 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0001657| ureteric bud development RARA;CAT;RARB GO:0010628| positive regulation of gene expression TRPV4;RARG;RARA GO:0007283| spermatogenesis CNR1;SOD1;RARA GO:0043277| apoptotic cell clearance RARA;ALOX15 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;PPARG;CYP1A1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent RARA;PPARG GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0008203| cholesterol metabolic process HMGCR;CAT;RXRA GO:0007612| learning VDAC1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0032526| response to retinoic acid PPARG;RXRA;RARA;RARG GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation RARB;CHRNA7;RARG;RARA;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRG;PLA2G1B;RARB;PPARG;RXRB;RXRA;RARG;RARA GO:0071300| cellular response to retinoic acid PPARG;RARA;RARG GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process RARB;CAT;RARG;GPX1;RARA;SOD1;PTGS2;HMGCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;RARB;TRPV4;TRPV1;RARG;RARA GO:0034097| response to cytokine stimulus PTGS2;RARA;AANAT GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0006355| regulation of transcription, DNA-dependent RARG;RARA;RXRA;RXRB;PPARG;RXRG;RARB GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;RARA GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0006367| transcription initiation from RNA polymerase II promoter RARA;RARG;RXRA;RXRB;PPARG;RARB;RXRG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT;RARA GO:0009750| response to fructose stimulus PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation RXRA;PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;CNR1;HMGCR GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0022008| neurogenesis DAGLA;RARB GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0043010| camera-type eye development CYP1A1;RXRA;RARG GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;RARB;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;RARA;CHRNA7 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0001890| placenta development SOD1;PPARG;RXRA GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;RARA;RARG;PPARG;RARB;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;RARA;CAT GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0043401| steroid hormone mediated signaling pathway RXRB;RXRA;PPARG;RXRG;RARB;RARG;RARA GO:0006351| transcription, DNA-dependent RARA;RARG;RARB;RXRG;RXRB;RXRA;PPARG GO:0019233| sensory perception of pain HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1;TRPA1;TRPV1 GO:0001889| liver development RARA;ACAT1;CYP1A1 GO:0043065| positive regulation of apoptotic process RARG;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;RARB;IDO1;SMPD1;PPARG GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0007507| heart development RXRA;PPARG GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0010629| negative regulation of gene expression RARA;OPRD1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0007565| female pregnancy RARA;IDO1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0051289| protein homotetramerization CRYZ;TRPA1;RXRA;TRPM8;RXRG;TRPV1;CAT GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;ALOX15;IDO1 GO:0016032| viral reproduction HTR2A;VDAC1;RXRA GO:0071498| cellular response to fluid shear stress PTGS2 18290:[DB14011 DB07848] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07848|5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 18291:[DB14011 DB05421] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05421|CP-122721 TACR1 common genes common pathways GO:0048266| behavioral response to pain TACR1;TRPV1 GO:0045471| response to ethanol SOD1;CNR1;OPRM1;TACR1;HMGCR;CAT GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;CNR2;PTGS2;TACR1;OPRM1;OPRD1 GO:0009408| response to heat TRPV1;TRPV3;TACR1;SOD1;TRPV2 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TACR1;ALOX15;IDO1;TRPV1 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;OPRD1;TACR1;OPRM1;GLRA3;HTR2A GO:0045907| positive regulation of vasoconstriction TACR1;PTGS2;HTR2A GO:0007165| signal transduction TACR1;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0009725| response to hormone stimulus ACAT1;TACR1 GO:0060083| smooth muscle contraction involved in micturition TRPV1;TACR1 GO:0043117| positive regulation of vascular permeability TACR1;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;TACR1;OPRM1 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;TACR1;PPARG GO:0042755| eating behavior OPRD1;OPRM1;TACR1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACAT1;AANAT;PTGS2;TACR1;CYP1A2 GO:0045777| positive regulation of blood pressure CNR1;TACR1 GO:0007611| learning or memory CHRNA7;TACR1;CNR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;TACR1;OPRM1 GO:0043278| response to morphine OPRM1;TACR1;CNR1 GO:0048265| response to pain TACR1;TRPV1;TRPA1 GO:0035094| response to nicotine CHRNA7;TACR1;CNR1 GO:0032355| response to estradiol stimulus CYP1A2;TACR1;PTGS2;CAT GO:0007186| G-protein coupled receptor signaling pathway CNR2;TACR1;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PPARG;GPR18 GO:0010193| response to ozone CAT;TACR1 18292:[DB14011 DB01155] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes CYP1A2 common pathways GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;IDO1;CYP1A1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;AANAT;ACAT1 GO:0045333| cellular respiration CYP1A2 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1;CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 18293:[DB14011 DB01800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01800|N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium ARSA common genes common pathways GO:0008152| metabolic process SMPD1;ARSA;ACAT1 GO:0006687| glycosphingolipid metabolic process ARSA;SMPD1 GO:0043312| neutrophil degranulation ARSA;ALOX5;CAT 18294:[DB14011 DB06921] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 18295:[DB14011 DB05431] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05431|MLN-977 ALOX5 common genes ALOX5 common pathways GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;ALOX5;GPX1;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT GO:2001300| ALOX5 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;IDO1;ALOX15;TRPV1 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0002540| leukotriene production involved in inflammatory response ALOX5 18296:[DB14011 DB02998] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;PGR;NR3C2;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C2;PGR;AR GO:0007623| circadian rhythm AANAT;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;PLA2G1B;NCOA2;PPARG GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;AR;CHRNA7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;NCOA2;PPARG;TRPV1;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0048511| rhythmic process AANAT;PPARG;NCOA2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport ABCC1;CACNA1I;TRPV1;ABCG2;TRPV2;AR GO:0010629| negative regulation of gene expression PGR;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C2;PGR;AR GO:0006351| transcription, DNA-dependent AR;PPARG;NCOA2;NR3C2;PGR GO:0008283| cell proliferation AR;GPX1;HTR1A;CYP1A1 GO:0007548| sex differentiation CYP17A1;AR GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;AR;PPARG;CYP1B1 GO:0019216| regulation of lipid metabolic process NCOA2;CYP1A1;PPARG;HMGCR;CNR1 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction NR3C2;CACNA1I;PGR;PLA2G1B;PPARG;GPR18;SMPD1;AR;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 18297:[DB14011 DB14635] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes CYP2D6;CYP3A4;CYP2C9;PPARG;CYP1A2 common pathways GO:0043066| negative regulation of apoptotic process GSTP1;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2B6;CYP2C9;CYP1A1;CYP1A2 GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;PLA2G1B;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0043312| neutrophil degranulation GSTP1;ALOX5;CAT GO:0042594| response to starvation PPARG;ACAT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;PPARG;TRPV1;TRPV4 GO:0045087| innate immune response PPARG GO:0030308| negative regulation of cell growth PPARG GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;IDO1 GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1;GSTP1 GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0032526| response to retinoic acid PPARG GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;GSR;GSTP1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0019369| arachidonic acid metabolic process DAGLA;CYP2D6;ALOX15;CYP1B1;FAAH GO:0071455| cellular response to hyperoxia PPARG GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;VDR GO:0099133| ABCC5;ABCC1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0006355| regulation of transcription, DNA-dependent VDR;PPARG GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2B6;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;CBR1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0030224| monocyte differentiation PPARG GO:0033993| response to lipid PPARG GO:0098869| GSTP1;GSTA1;GSR;PTGS1;GPX1;CAT;PTGS2 GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;VDR;CHRNA7;TRPV4;TRPM8 GO:0043388| positive regulation of DNA binding PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG;GSTP1 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0017144| drug metabolic process CBR1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP2B6 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP2B6;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;GSTP1 GO:0046697| decidualization VDR;PTGS2 GO:0006810| transport TRPV2;ABCG2;ABCC5;TRPV1;ABCB1;CACNA1I;ABCC1 GO:0015909| long-chain fatty acid transport PPARG GO:0010468| regulation of gene expression CYP1A2 GO:0010628| positive regulation of gene expression VDR;TRPV4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;VDR GO:0031000| response to caffeine PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0048511| rhythmic process AANAT;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0043200| response to amino acid stimulus GLRB;GSTP1;GLRA3 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;GSTA1;VDAC1;CBR1 GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV1;CACNA1I;ABCB1;TRPV4;VDAC1;ABCG2;TRPM8;ABCC5;CACNA1G;ABCC1;TRPA1 GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0008152| metabolic process SMPD1;GSTM1;GSTA1;GSTP1;ACAT1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C19;CYP1B1;GSTP1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0006351| transcription, DNA-dependent VDR;PPARG GO:0051100| negative regulation of binding CYP2D6 GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0048469| cell maturation PPARG GO:0045471| response to ethanol GSTP1;OPRM1;HMGCR;SOD1;CNR1;CAT GO:0043603| cellular amide metabolic process CYP2C9 GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;VDR;TRPV2;TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG;GSTP1 GO:0050872| white fat cell differentiation PPARG GO:0007595| lactation SLC29A1;VDR GO:0042752| regulation of circadian rhythm PPARG GO:0031667| response to nutrient levels GSTP1;SOD1 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0019371| cyclooxygenase pathway PTGS2;PTGS1;CBR1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2B6;CYP2C9;CYP2C19 GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0008209| androgen metabolic process CYP3A4 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;VDR GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG GO:1905461| PPARG GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0042178| xenobiotic catabolic process CRYZ;GSTM1 GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0055088| lipid homeostasis PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0006749| glutathione metabolic process SOD1;GPX1;GSTM1;GSTP1;GSTA1;GSR GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;VDR;PTGS2;OPRM1 GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0032930| positive regulation of superoxide anion generation SOD1;GSTP1 GO:0043627| response to estrogen stimulus PPARG GO:0009636| response to toxin CYP1A1;CYP1B1;GSTP1;GPX1;CAT GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TRPA1;PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0019627| urea metabolic process CYP2C9 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 18298:[DB14011 DB02813] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways GO:0008152| metabolic process ACAT1;HEXB;SMPD1 GO:0006687| glycosphingolipid metabolic process SMPD1;HEXB GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;HEXB;CHRNA7;TRPM8;TRPV4 GO:0007605| sensory perception of sound SOD1;GPX1;HEXB GO:0007626| locomotory behavior HEXB;SOD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HEXB;PLA2G1B;PPARG GO:0043312| neutrophil degranulation ALOX5;HEXB;CAT GO:0050905| neuromuscular process GLRB;GLRA1;HEXB 18299:[DB14011 DB04318] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways GO:0030199| collagen fibril organization CYP1B1;MMP11 18300:[DB14011 DB02177] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02177|1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine ITGAL common genes common pathways GO:0043312| neutrophil degranulation ITGAL;CAT;ALOX5 GO:0007155| cell adhesion CYP1B1;ITGAL GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ITGAL;PTGS2;CNR2;PTGS1;ALOX5 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;ITGAL;HTR2A;CNR1;GPR12;GPR55;HTR1A 18301:[DB14011 DB02347] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02347|2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid GRIA2 common genes common pathways GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GRIA2;GLRA1;TRPA1;GLRB;TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;GLRA1;GRIA2;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0007165| signal transduction GRIA2;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006811| ion transport TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPA1;GLRA1;CACNA1G;CHRNA7;GRIA2;TRPV2;GLRA3;TRPV3;CACNA1H GO:0007268| synaptic transmission GRIA2;GLRA3;HTR2A;OPRD1;OPRM1;VDAC1;GLRB;GLRA1;CACNA1G 18302:[DB14011 DB02142] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways GO:0008152| metabolic process ACAT1;BCAT2;SMPD1 GO:0006550| isoleucine catabolic process BCAT2;ACAT1 GO:0009083| branched chain family amino acid catabolic process ACAT1;BCAT2 18303:[DB14011 DB06912] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06912|UNDECA-3,7-DIENE-1,3,7,11-TETRACARBALDEHYDE LYZ common genes common pathways GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B GO:0043312| neutrophil degranulation LYZ;ALOX5;CAT GO:0001895| retina homeostasis SOD1;LYZ GO:0006954| inflammatory response IDO1;ALOX15;LYZ;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0008152| metabolic process LYZ;SMPD1;ACAT1 18304:[DB14011 DB12334] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12334|Milataxel TUBB1;TUBB common genes common pathways GO:0043312| neutrophil degranulation TUBB;ALOX5;CAT 18305:[DB14011 DB06157] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1;ATP1A1 GO:0034976| response to endoplasmic reticulum stress ATP2A2;ALOX15 GO:0006811| ion transport GLRA3;ATP1A1;CACNA1H;ATP2A2;TRPV3;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1 GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;OPRM1;CACNA1H;ATP2A2;TRPV3;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0006816| calcium ion transport CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;CACNA1H;ATP2A2;TRPV3 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0086002| CACNA1G;ATP1A1 GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;CHRNA7;ATP2A2;ATP1A1;GLRA3 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;GPR12;HTR2A;ATP2A2 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;ATP1A1;CAT GO:0007155| cell adhesion ATP2A2;CYP1B1 GO:0034599| cellular response to oxidative stress GSR;SOD1;ATP2A2;CAT;GPX1 18306:[DB14011 DB08082] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08082|N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE MAOB common genes common pathways GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT;MAOB GO:0010269| response to selenium ion GPX1;MAOB GO:0009636| response to toxin GPX1;CAT;CYP1B1;MAOB;CYP1A1 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0042493| response to drug ABCG2;SMPD1;ABCC1;MAOB;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0022900| electron transport chain CYP1A2;MAOB;GSR;IDO1 GO:0055114| oxidation-reduction process MAOB;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0032496| response to lipopolysaccharide IDO1;MAOB;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 18307:[DB14011 DB07462] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0008210| estrogen metabolic process CYP1B1;COMT GO:0048265| response to pain TRPA1;COMT;TRPV1 GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;ABCC1;COMT;TRPA1;CYP1A1;PPARG;ABCG2 GO:0032259| methylation CYP1A2;COMT GO:0007614| short-term memory CHRNA7;COMT GO:0007612| learning PTGS2;COMT;VDAC1 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;IDO1;COMT;CYP1A1 GO:0043627| response to estrogen stimulus PPARG;COMT GO:0051930| regulation of sensory perception of pain COMT;OPRM1;OPRD1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;COMT;CYP1A2;PTGS2;ACAT1;AANAT GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0032502| developmental process CYP1A1;COMT GO:0007565| female pregnancy IDO1;COMT 18308:[DB14011 DB09303] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09303|Evolocumab PCSK9 common genes common pathways GO:0008202| steroid metabolic process CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CYP3A4;CYP1A2;CYP3A7;HMGCR;PCSK9 GO:0006644| phospholipid metabolic process PLA2G1B;NAPEPLD;PCSK9 GO:0006915| apoptotic process GPX1;PCSK9;VDAC1 GO:0001822| kidney development PCSK9;CAT GO:0043523| regulation of neuron apoptosis GPX1;PCSK9 GO:0008203| cholesterol metabolic process PCSK9;HMGCR;CAT GO:0006641| triglyceride metabolic process CAT;GPX1;PCSK9 GO:0022008| neurogenesis PCSK9;DAGLA GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PCSK9 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PCSK9;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9 GO:0001889| liver development PCSK9;ACAT1;CYP1A1 18309:[DB14011 DB01284] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01284|Tetracosactide MC2R common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1;MC2R GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18;MC2R GO:0007218| neuropeptide signaling pathway GLRB;GLRA1;MC2R;GLRA3;OPRM1;OPRD1 GO:0001890| placenta development MC2R;PPARG;SOD1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7;SMPD1;MC2R;GPR18;PPARG;PLA2G1B;CACNA1I 18310:[DB14011 DB03484] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03484|L-Alpha-Glycerophosphorylethanolamine ANXA5 common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;ANXA5;HTR1A;CNR1;GPR12;HTR2A;CHRNA7 GO:0010033| response to organic substance ANXA5;SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0002576| platelet degranulation ANXA5;SOD1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ANXA5 18311:[DB14011 DB05913] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05913|OSI-930 KIT;FLT1 common genes common pathways GO:0046686| response to cadmium ion CAT;KIT GO:0001541| ovarian follicle development KIT;SOD1 GO:0031532| actin cytoskeleton reorganization KIT;TRPV4 GO:0045766| positive regulation of angiogenesis CYP1B1;FLT1;CHRNA7 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7;KIT GO:0007283| spermatogenesis KIT;SOD1;CNR1 GO:0010628| positive regulation of gene expression KIT;TRPV4 GO:0043406| positive regulation of MAP kinase activity HTR2A;FLT1;KIT GO:0006687| glycosphingolipid metabolic process SMPD1;KIT GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FLT1;KIT;CAT GO:0048514| blood vessel morphogenesis CYP1B1;FLT1 GO:0046427| positive regulation of JAK-STAT cascade KIT;CYP1B1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;KIT GO:0060326| cell chemotaxis KIT;ABCC1 GO:0042127| regulation of cell proliferation PTGS2;KIT;PTGS1 GO:0008284| positive regulation of cell proliferation CHRNA7;KIT;HTR2A;HTR1A;HMGCR;FLT1;PTGS2 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;KIT;CHRNA7 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;KIT GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS2;CNR2;PTGS1;ALOX5;KIT GO:0030217| T cell differentiation GPR18;KIT GO:0048565| digestive tract development KIT;CYP1A1 GO:0008542| visual learning KIT;HMGCR GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;PPARG GO:0001525| angiogenesis FLT1;PTGS2;CYP1B1 GO:0035556| intracellular signal transduction PLA2G1B;KIT GO:0009314| response to radiation PTGS2;OPRM1;CAT;KIT 18312:[DB14011 DB00438] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0098656| SLC22A6;VDAC1 GO:0006811| ion transport GLRA3;SLC22A5;SLC15A2;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;GLRA1;SLC15A1;CACNA1G;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A5 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0006810| transport SLC15A1;ABCC1;ABCG2;CACNA1I;TRPV1;SLC15A2;TRPV2 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC15A2;SLC22A5;TRPV2;ABCC1;CACNA1G;SLC22A6;TRPA1;SLC15A1;VDAC1;TRPV4;CACNA1I;TRPV1;TRPM8;ABCG2 18313:[DB14011 DB04010] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04010|2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide PARP1 common genes common pathways GO:0010332| response to gamma radiation GPX1;PARP1 GO:0032869| cellular response to insulin stimulus PARP1;PPARG;PLA2G1B GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0071294| cellular response to zinc ion PARP1;GLRA1 GO:0006915| apoptotic process VDAC1;PARP1;GPX1 GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;PLA2G1B;PPARG GO:0034599| cellular response to oxidative stress GSR;PARP1;SOD1;GPX1;CAT 18314:[DB14011 DB06124] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways GO:0051592| response to calcium ion AANAT;CAPN3 GO:0071277| cellular response to calcium ion ALOX15;CAPN3 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;CAPN3 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7;CAPN3;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;CAPN3 GO:0007517| muscle organ development CACNA1H;CAPN3 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CAPN3 GO:0006915| apoptotic process VDAC1;CAPN3;GPX1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CAPN3 GO:0046716| muscle cell homeostasis SOD1;CAPN3 18315:[DB14011 DB12200] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12200|Tivantinib MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;MET GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MET GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;MET;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0008283| cell proliferation HTR1A;MET;GPX1;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway MET;TRPV1;TRPA1 18316:[DB14011 DB06366] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06366|Pertuzumab ERBB2 common genes common pathways GO:0007507| heart development PPARG;ERBB2 GO:0007399| nervous system development ERBB2;SMPD1;GLRB GO:0006351| transcription, DNA-dependent PPARG;ERBB2 GO:0007166| cell surface receptor linked signaling pathway ERBB2;TRPA1;TRPV1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ERBB2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ERBB2 GO:0007165| signal transduction ERBB2;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;ERBB2 GO:0008283| cell proliferation CYP1A1;ERBB2;GPX1;HTR1A GO:0042060| wound healing ALOX15;ERBB2;OPRM1 GO:0051897| positive regulation of protein kinase B signaling cascade ERBB2;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ERBB2 GO:0071363| cellular response to growth factor stimulus CAT;ERBB2;OPRD1;TRPV1 GO:0043406| positive regulation of MAP kinase activity HTR2A;ERBB2 GO:0010628| positive regulation of gene expression TRPV4;ERBB2 18317:[DB14011 DB04590] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways GO:0009725| response to hormone stimulus ACAT1;F7 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;F7;CYP1A2;PTGS2;ACAT1;AANAT GO:0043627| response to estrogen stimulus F7;PPARG GO:0031667| response to nutrient levels F7;SOD1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;F7 GO:0031100| organ regeneration PPARG;F7 GO:0001666| response to hypoxia CAT;CHRNA7;F7;CYP1A1 GO:0007623| circadian rhythm F7;AANAT GO:0051897| positive regulation of protein kinase B signaling cascade F7;GPX1 18318:[DB14011 DB05668] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05668|Palifosfamide DNMT1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;PPARG;TRPV1;TRPV4 GO:0032259| methylation CYP1A2;DNMT1 GO:0071230| cellular response to amino acid stimulus GLRA1;DNMT1 GO:0042127| regulation of cell proliferation DNMT1;PTGS1;PTGS2 GO:0006355| regulation of transcription, DNA-dependent DNMT1;PPARG GO:0010468| regulation of gene expression DNMT1;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;DNMT1 GO:0010628| positive regulation of gene expression TRPV4;DNMT1 GO:0006351| transcription, DNA-dependent PPARG;DNMT1 18319:[DB14011 DB04758] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0031100| organ regeneration PPARG;F7 GO:0032355| response to estradiol stimulus F7;CAT;CYP1A2;PTGS2 GO:0001666| response to hypoxia F7;CYP1A1;CHRNA7;CAT GO:0007623| circadian rhythm F7;AANAT GO:0051897| positive regulation of protein kinase B signaling cascade F7;GPX1 GO:0009725| response to hormone stimulus F7;ACAT1 GO:0043627| response to estrogen stimulus PPARG;F7 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;F7;PTGS2;CYP1A2;ACAT1;AANAT GO:0031667| response to nutrient levels SOD1;F7 18320:[DB14011 DB05404] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05404|AZD 3355 TP53 common genes common pathways GO:0042493| response to drug ABCC1;TP53;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;TP53 GO:0045893| positive regulation of transcription, DNA-dependent TP53;PPARG GO:0007569| cell aging TP53;SOD1 GO:0055093| response to hyperoxia CAT;TP53;CYP1A1 GO:0010243| response to organic nitrogen PTGS2;TRPV1;TP53 GO:0042060| wound healing OPRM1;ALOX15;TP53 GO:0030308| negative regulation of cell growth PPARG;TP53 GO:0032526| response to retinoic acid PPARG;TP53 GO:0046677| response to antibiotic CYP1A1;TP53;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TP53;PLA2G1B GO:0043066| negative regulation of apoptotic process TP53;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0034097| response to cytokine stimulus PTGS2;AANAT;TP53 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;TP53 GO:0043200| response to amino acid stimulus GLRA3;GLRB;TP53 GO:0006915| apoptotic process GPX1;TP53;VDAC1 GO:0010628| positive regulation of gene expression TRPV4;TP53 GO:0048511| rhythmic process AANAT;PPARG;TP53 GO:0045892| negative regulation of transcription, DNA-dependent TP53;PPARG GO:0031000| response to caffeine TP53;PPARG GO:0051262| protein tetramerization HMGCR;CAT;TP53 GO:0034605| cellular response to heat TP53;TRPV4;TRPV1;PTGS2 GO:0071456| cellular response to hypoxia TP53;PTGS2;OPRD1;SLC29A1 GO:0007568| aging CYP1A1;TP53;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;TP53 GO:0051289| protein homotetramerization CAT;CRYZ;TRPA1;TP53;TRPM8;TRPV1 GO:0016032| viral reproduction VDAC1;TP53;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TP53;HTR2A GO:0045471| response to ethanol CAT;OPRM1;HMGCR;SOD1;CNR1;TP53 GO:0006351| transcription, DNA-dependent PPARG;TP53 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;TP53;IDO1;CYP1B1;TRPV1 GO:0051974| negative regulation of telomerase activity PPARG;TP53 GO:0008283| cell proliferation CYP1A1;TP53;HTR1A;GPX1 GO:0009411| response to UV CAT;TP53 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;TP53;PTGS2;CYP1A2;ACAT1;AANAT GO:0008285| negative regulation of cell proliferation TP53;PPARG;CYP1B1;PTGS2;OPRM1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;TP53 GO:0034644| cellular response to UV TP53;PTGS2 GO:0010332| response to gamma radiation GPX1;TP53 18321:[DB14011 DB06101] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR;FLT4 GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0016032| viral reproduction KDR;VDAC1;HTR2A GO:0001525| angiogenesis FLT4;CYP1B1;KDR;PTGS2;FLT1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;FLT4;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade FLT4;TRPV4;KDR;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0045766| positive regulation of angiogenesis FLT1;CHRNA7;CYP1B1;KDR GO:0043406| positive regulation of MAP kinase activity FLT1;HTR2A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FLT1;KDR GO:0048514| blood vessel morphogenesis CYP1B1;FLT4;FLT1 GO:0046330| positive regulation of JNK cascade FLT4;TRPV4 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;FLT1;PTGS2;KDR;FLT4 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;KDR;FLT4 18322:[DB14011 DB03691] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03691|WRR-112 CTSF common genes common pathways 18323:[DB14011 DB04461] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04461|Coproporphyrinogen III UROD common genes common pathways 18324:[DB14011 DB07039] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways GO:0008283| cell proliferation HTR1A;GPX1;AR;CYP1A1 GO:0007548| sex differentiation AR;CYP17A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;AR;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport AR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;AR 18325:[DB14011 DB11059] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways GO:0055085| transmembrane transport ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;SLC2A1;TRPV3 GO:0015758| glucose transport SLC2A1;PLA2G1B GO:0006970| response to osmotic stress SLC2A1;TRPV4 GO:0071260| cellular response to mechanical stimulus PTGS2;SLC2A1 GO:0007565| female pregnancy IDO1;SLC2A1 GO:0042908| xenobiotic transport ABCG2;ABCC1;SLC2A1 GO:0050796| regulation of insulin secretion CNR1;SLC2A1 GO:0032868| response to insulin stimulus TRPV4;SLC2A1;AANAT;CAT 18326:[DB14011 DB06973] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06973|4,4'-PROPANE-2,2-DIYLDIPHENOL ESRRG common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESRRG GO:0045893| positive regulation of transcription, DNA-dependent ESRRG;PPARG GO:0006355| regulation of transcription, DNA-dependent ESRRG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;PLA2G1B;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESRRG GO:0006351| transcription, DNA-dependent ESRRG;PPARG 18327:[DB14011 DB04238] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04238|N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18328:[DB14011 DB03403] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;CMPK1 GO:0015949| nucleobase-containing small molecule interconversion GSR;CMPK1 GO:0008152| metabolic process UCK2;SMPD1;ACAT1 18329:[DB14011 DB00685] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes CYP1A2 common pathways GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;TOP2A;CYP1B1;TRPV1;IDO1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1A1;CYP2C9 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;GPX1;ALOX5;PTGS1 18330:[DB14011 DB02712] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02712|Sorbinil AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0022900| electron transport chain AKR1B1;GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;AKR1B1;CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;AKR1B1;PPARG;CYP1A1;TRPA1 18331:[DB14011 DB08497] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;CASP3;AANAT;ACAT1 GO:0009411| response to UV CASP3;CAT GO:0006919| activation of caspase activity PPARG;CASP3 GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;CASP3;TRPA1 GO:0043065| positive regulation of apoptotic process CASP3;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0035556| intracellular signal transduction CASP3;PLA2G1B GO:0045165| cell fate commitment CASP3;PPARG GO:0007507| heart development CASP3;PPARG GO:0001666| response to hypoxia CASP3;CAT;CHRNA7;CYP1A1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CASP3;TRPA1;PPARG;CYP1A1 GO:0043200| response to amino acid stimulus GLRB;CASP3;GLRA3 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0006915| apoptotic process CASP3;GPX1;VDAC1 GO:0007605| sensory perception of sound GPX1;CASP3;SOD1 GO:0009611| response to wounding CYP1A1;GPX1;CASP3 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;CASP3 GO:0035094| response to nicotine CNR1;CASP3;CHRNA7 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CASP3;CAT GO:0071407| cellular response to organic cyclic compound CASP3;CYP1A1;CYP1B1 GO:0046677| response to antibiotic SOD1;CASP3;CYP1A1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;CASP3;SOD1;PTGS2;HMGCR GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0032496| response to lipopolysaccharide CASP3;CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;CYP1A1 GO:0042060| wound healing OPRM1;CASP3;ALOX15 GO:0007611| learning or memory CASP3;CHRNA7;CNR1 18332:[DB14011 DB08155] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010033| response to organic substance CA2;CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 GO:0001822| kidney development CA2;CAT 18333:[DB14011 DB04109] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04109|[4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]Benzamidine PRSS3 common genes common pathways GO:0043542| endothelial cell migration PRSS3;CYP1B1 GO:0043312| neutrophil degranulation ALOX5;CAT;PRSS3 GO:0009235| cobalamin metabolic process ABCC1;PRSS3 18334:[DB14011 DB07428] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG;HBB GO:0051291| protein heterooligomerization GLRB;HBA1;HBB;GLRA1 GO:0042542| response to hydrogen peroxide HBB;TRPA1;HBA1;SOD1;CAT;GPX1 GO:0010942| positive regulation of cell death HBA1;HBB;PTGS2 GO:0098869| HBA1;HBB;GSR;PTGS2;CAT;GPX1;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HBB;OPRM1;PTGS2 GO:0042744| hydrogen peroxide catabolic process HBA1;HBB;CAT;GPX1 GO:0043312| neutrophil degranulation ALOX5;CAT;HBB 18335:[DB14011 DB04074] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport CACNA1G;ABCC1;SLC16A3;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;SLC16A7;CACNA1H;TRPV3;TRPV2;SLC16A1 GO:0006550| isoleucine catabolic process ACAT1;BCAT2 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;SLC16A1 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1A1;CYP1B1 GO:0032094| response to food OPRM1;SLC16A1;CYP1A1 GO:0009083| branched chain family amino acid catabolic process ACAT1;BCAT2 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0008152| metabolic process ACAT1;SMPD1;BCAT2 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG;SLC16A1;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR 18336:[DB14011 DB02180] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02180|Myristoyl-Coa NMT1;NMT2 common genes common pathways 18337:[DB14011 DB03239] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways GO:0006810| transport ABCC1;ABCG2;TRPV1;CACNA1I;TTR;TRPV2 GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process CYP1B1;TTR 18338:[DB14011 DB02354] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02354|4-{[1-Methyl-5-(2-Methyl-Benzoimidazol-1-Ylmethyl)-1h-Benzoimidazol-2-Ylmethyl]-Amino}-Benzamidine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18339:[DB14011 DB07548] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07548|2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT 18340:[DB14011 DB07067] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0043542| endothelial cell migration CYP1B1;DPP4 18341:[DB14011 DB05191] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05191|Atl146e ADORA2A common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;ADORA2A;CYP1B1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1;ADORA2A GO:0042755| eating behavior ADORA2A;OPRM1;OPRD1 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;ADORA2A;PPARG GO:0001975| response to amphetamine ADORA2A;SOD1;CNR2 GO:0007600| sensory perception ADORA2A;TRPV2;OPRM1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;IDO1;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;ADORA2A GO:0043524| negative regulation of neuron apoptosis SOD1;ADORA2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADORA2A GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0031000| response to caffeine ADORA2A;PPARG GO:0050714| positive regulation of protein secretion ADORA2A;PLA2G1B GO:0006915| apoptotic process VDAC1;ADORA2A;GPX1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;ADORA2A;PPARG;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0050728| negative regulation of inflammatory response ADORA2A;CNR2 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ADORA2A GO:0006355| regulation of transcription, DNA-dependent ADORA2A;PPARG GO:0042311| vasodilation GPX1;ADORA2A GO:0007626| locomotory behavior SOD1;OPRM1;ADORA2A GO:0060079| regulation of excitatory postsynaptic membrane potential ADORA2A;GLRA1;TRPV1;GLRB;GLRA3;OPRM1;CHRNA7;SLC29A1 18342:[DB14011 DB01834] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways GO:0032869| cellular response to insulin stimulus GSTP1;PLA2G1B;PPARG GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;GSTP1;CYP1A1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0006749| glutathione metabolic process GSTM1;GSTP1;GSR;SOD1;GPX1 GO:0042178| xenobiotic catabolic process GSTM1;CRYZ GO:0045471| response to ethanol GSTP1;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;GSTP1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0008152| metabolic process ACAT1;GSTM1;SMPD1;GSTP1 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:1904706| GSTP1;PPARG GO:0032355| response to estradiol stimulus GSTP1;PTGS2;CYP1A2;CAT GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0098869| GSTP1;GSR;PTGS1;GPX1;CAT;PTGS2 GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0034599| cellular response to oxidative stress GSTP1;GSR;GPX1;CAT;SOD1 GO:0000302| response to reactive oxygen species GSTP1;SOD1;CAT;GPX1 GO:0043312| neutrophil degranulation CAT;ALOX5;GSTP1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;GSTP1 18343:[DB14011 DB00859] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00859|Penicillamine SLCO1B1 common genes common pathways GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;SLCO1B1;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLCO1B1;TRPV2;ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCG2 18344:[DB14011 DB12458] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways GO:0006821| chloride transport GLRB;GLRA1;GABRB3;GABRG2;GLRA3;GABRA1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GABRB3;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0009791| post-embryonic development CYP1A2;GABRG2 GO:0006811| ion transport CACNA1H;TRPV3;GABRG2;GABRA1;GLRA3;TRPV2;GABRB3;CHRNA7;CACNA1G;TRPA1;GLRA1;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8 GO:0060078| regulation of postsynaptic membrane potential GABRA1;CHRNA7 GO:1902476| GABRB3;GABRG2;GABRA1;GLRA3;GLRB;GLRA1 GO:0043524| negative regulation of neuron apoptosis GABRB3;SOD1 GO:0007268| synaptic transmission HTR2A;GLRA3;GABRG2;OPRD1;OPRM1;VDAC1;GLRB;GLRA1;CACNA1G GO:0007605| sensory perception of sound GPX1;GABRB3;SOD1 GO:0006810| transport TRPV2;GABRB3;GABRG2;GABRA1;TRPV1;CACNA1I;ABCG2;ABCC1 GO:0060080| regulation of inhibitory postsynaptic membrane potential GABRB3;GLRA1 GO:0034220| ion transmembrane transport TRPA1;GLRA1;GLRB;TRPV1;GABRG2;GABRA1;GLRA3;GABRB3;CHRNA7 GO:0043523| regulation of neuron apoptosis GPX1;GABRB3 18345:[DB14011 DB00655] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes ABCG2;CYP1A1;CYP2C9;CYP1A2;CYP1B1;CYP3A5;CYP3A4 common pathways GO:0098869| ALB;GSR;GPX1;PTGS1;CAT;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TRPV1 GO:0010041| response to iron(III) ion CYP1A1 GO:0042574| retinal metabolic process CYP1B1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2B6;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0009611| response to wounding GPX1;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP2B6;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0010468| regulation of gene expression CYP1A2;AR GO:0007568| aging CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0048514| blood vessel morphogenesis CYP1B1 GO:0006810| transport TRPV2;AR;ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0010193| response to ozone CYP2E1;CAT GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0071615| oxidative deethylation CYP1A2 GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPV2;SLC22A8;SLCO1B1;CACNA1H;TRPV3;SLCO1A2;ABCG2;SLCO2B1;TRPM8;ABCB1;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0002576| platelet degranulation SOD1;ALB GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ESR2;PLA2G1B;ESR1;AR GO:0008284| positive regulation of cell proliferation AR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0009615| response to virus CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP2B6;CYP1A1;CYP2C9;CYP2E1;CYP4A11;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;TRPV4;TRPV1;PPARG;AR;ESR1 GO:0007155| cell adhesion CYP1B1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;CYP1A1;IDO1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0030199| collagen fibril organization CYP1B1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0009812| flavonoid metabolic process CYP1A1 GO:0033344| cholesterol efflux ABCG2 GO:0043542| endothelial cell migration CYP1B1 GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0019369| arachidonic acid metabolic process CYP4A11;FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0010243| response to organic nitrogen TRPV1;PTGS2;CYP2E1 GO:0009308| amine metabolic process CYP1A1 GO:0006694| steroid biosynthetic process HMGCR;CYP19A1;CYP17A1 GO:0008210| estrogen metabolic process CYP1B1 GO:0015886| heme transport ABCG2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG;AR;ESR1 GO:0061298| retina vasculature development in camera-type eye CYP1B1 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;CYP2E1;SOD1;HTR2A;CYP1A2;PTGS2 GO:0006691| leukotriene metabolic process ALOX5;CYP4A11;ALOX15;ABCC1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG;AR;ESR1 GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0006631| fatty acid metabolic process PTGS2;CYP4A11;PTGS1;ALOX15 GO:0022900| electron transport chain CYP1A2;CYP19A1;GSR;IDO1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;ESR2;PPARG GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 GO:0055114| oxidation-reduction process CYP19A1;CYP1A1;CYP2C9;CRYZ;CYP2B6;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;PTGS2;CYP3A7;CYP1A2;CYP4A11;HMGCR;CYP3A4;CYP2E1;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0043010| camera-type eye development CYP1A1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;ESR2;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;ESR1;OPRD1;OPRM1;CNR2;CHRNA7;AR GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP4A11;CYP1A2 GO:0006641| triglyceride metabolic process CAT;GPX1;CYP2E1 GO:1900087| CYP1A1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0019216| regulation of lipid metabolic process CNR1;CYP4A11;HMGCR;PPARG;CYP1A1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV4;TRPV1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0032502| developmental process CYP1A1 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB GO:0009791| post-embryonic development CYP1A2 GO:0030336| negative regulation of cell migration CYP1B1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0017143| insecticide metabolic process CYP1A1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1 GO:0098656| VDAC1;SLC22A8 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0046466| membrane lipid catabolic process CYP1B1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0006811| ion transport TRPV3;SLCO1A2;CACNA1H;SLCO1B1;SLC22A8;GLRA3;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;SLCO2B1 GO:0045333| cellular respiration CYP1A2 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 GO:0019627| urea metabolic process CYP2C9 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0007548| sex differentiation AR;CYP17A1 GO:0009624| response to nematode CYP1A1 GO:0002930| CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0001895| retina homeostasis ALB;SOD1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP2E1;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;NAAA;PTGS1;GPX1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0042572| retinol metabolic process CYP1B1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0009692| ethylene metabolic process CYP1A1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0045471| response to ethanol CAT;CYP2E1;SOD1;CNR1;OPRM1;HMGCR GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG;AR;ESR1 GO:0006351| transcription, DNA-dependent AR;ESR1;ESR2;PPARG GO:0070988| demethylation CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2;ESR1 GO:0043603| cellular amide metabolic process CYP2C9 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0048565| digestive tract development CYP1A1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0009635| response to herbicide CYP1A1 GO:0008209| androgen metabolic process CYP3A4;ESR1;CYP19A1 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1 GO:0046415| urate metabolic process ABCG2 18346:[DB14011 DB03268] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03268|RU82197 SRC common genes common pathways GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0045453| bone resorption SRC;GPR55 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;SRC;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;SRC GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;GPX1;SRC GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;SRC;PTGS2;CNR1;SOD1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0002376| immune system process SRC;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;SRC;CAT GO:0009615| response to virus SRC;CYP1A1 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;SRC;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 18347:[DB14011 DB03225] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03225|D-Tryptophan DAO;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;DAO;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A1;CYP2C9;CRYZ GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1;CACNA1H;TRPV3;SLC16A10;TRPV2 18348:[DB14011 DB06911] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06911|D-leucyl-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;F2;PPARG;GPR18 18349:[DB14011 DB00902] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00902|Methdilazine HRH1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;HRH1;OPRM1;CNR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;HRH1;OPRD1;OPRM1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;HRH1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;HRH1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0007613| memory CHRNA7;HRH1;PTGS2;HTR2A;CNR1 GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;HRH1;ALOX15;IDO1;TRPV1 GO:0008542| visual learning HRH1;HMGCR 18350:[DB14011 DB03593] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03593|N7-Methyl-Guanosine-5'-Monophosphate DCPS common genes common pathways 18351:[DB14011 DB05087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GABRA5;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;GABRA6;HTR1A;HTR2A;CNR1;GPR12 GO:0007420| brain development GABRA5;ACAT1 GO:0006821| chloride transport GABRA2;GLRB;GLRA1;GABRA3;GABRA5;GLRA3;GABRA1;GABRA6;GABRA4 GO:0001662| behavioral fear response HTR1A;GABRA5;VDAC1 GO:0006811| ion transport CHRNA7;TRPV2;GABRA6;GABRA4;GLRA3;GABRA1;CACNA1H;TRPV3;GABRA2;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA1;TRPA1;CACNA1G;GABRA5;GABRA3 GO:0060078| regulation of postsynaptic membrane potential GABRA1;CHRNA7 GO:1902476| GLRB;GABRA2;GABRA3;GABRA5;GLRA1;GABRA4;GABRA6;GABRA1;GLRA3 GO:0043524| negative regulation of neuron apoptosis GABRA5;SOD1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;CACNA1G;GABRA5;GLRA1;VDAC1;GLRB GO:0007605| sensory perception of sound GABRA5;GPX1;SOD1 GO:0006810| transport GABRA5;ABCC1;GABRA3;TRPV1;CACNA1I;ABCG2;GABRA4;GABRA6;GABRA1;TRPV2 GO:0034220| ion transmembrane transport TRPA1;GLRA1;GABRA5;GABRA3;GABRA2;TRPV1;GLRB;GABRA4;GABRA6;GABRA1;GLRA3;CHRNA7 GO:0043523| regulation of neuron apoptosis GABRA5;GPX1 18352:[DB14011 DB04840] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes CYP1A1;CYP2D6 common pathways GO:0043010| camera-type eye development CYP1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:1900087| CYP1A1 GO:0032502| developmental process CYP1A1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0017143| insecticide metabolic process CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0009624| response to nematode CYP1A1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6 GO:0009692| ethylene metabolic process CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0051100| negative regulation of binding CYP2D6 GO:0070988| demethylation CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;CACNA1G;SLC6A2;GLRA1;GLRB;VDAC1 GO:0010041| response to iron(III) ion CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0009611| response to wounding CYP1A1;GPX1 GO:0007568| aging CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0006810| transport SLC6A2;ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2;TRPV2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV1;VDAC1;TRPV4;ABCB1;CACNA1I;TRPM8;ABCG2;SLC6A2;ABCC1;CACNA1G;TRPA1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0009615| response to virus CYP1A1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;CYP1A1;IDO1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0009308| amine metabolic process CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;CYP2D6;DAGLA;ALOX15 GO:0048265| response to pain TRPV1;SLC6A2;TRPA1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCB1;ABCG2;ABCC1;SLC6A2;SMPD1;PPARG;CYP1A1;TRPA1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1A1;CYP2C9;CRYZ 18353:[DB14011 DB04562] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04562|Tricarballylic Acid ACO2 common genes common pathways GO:0001889| liver development ACO2;CYP1A1;ACAT1 GO:0008152| metabolic process ACAT1;ACO2;SMPD1 GO:0035900| response to isolation stress ACO2;NAPEPLD 18354:[DB14011 DB09304] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09304|Setiptiline ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7 common genes HTR1A;HTR2A common pathways GO:0042053| regulation of dopamine metabolic process HTR1A GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C;HTR2A GO:0051781| positive regulation of cell division CAT;HTR2B GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0001662| behavioral fear response HTR1A;VDAC1;HTR2C GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1B;HTR7;HTR1A GO:0043267| negative regulation of potassium ion transport HTR2A GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;HTR1D GO:0006811| ion transport CACNA1G;HTR3E;GLRA1;TRPA1;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;HTR3A;TRPM8;CACNA1H;TRPV3;HTR3C;GLRA3;TRPV2;HTR3B;HTR3D;CHRNA7 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADRA2C GO:0032229| negative regulation of synaptic transmission, GABAergic HTR1B;CNR2 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1 GO:0045777| positive regulation of blood pressure ADRA2B;CNR1 GO:0001819| positive regulation of cytokine production SOD1;HTR2B;ADRA2A GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0045907| positive regulation of vasoconstriction HTR2A;ADRA2C;PTGS2 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;HTR2B GO:0006939| smooth muscle contraction HTR2A;HTR1D;HTR2B;HTR7 GO:0007165| signal transduction SMPD1;HTR3E;GPR18;PPARG;HTR7;HTR3A;HTR1B;CACNA1I;PLA2G1B;HTR1F;ADRA2A;HTR2B;HTR6;HTR2C;HTR1D;OPRD1;HTR4;CNR2;OPRM1;HTR2A;GPR12;CNR1;ADRA2B;ADRA2C;HTR1A;HTR3C;GPR55;HTR3B;HTR3D;HTR1E;CHRNA7 GO:0007610| behavior HTR2A;HTR1A;HTR2C;HTR2B;HTR1B GO:0046718| entry of virus into host cell HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway HTR1E;OPRM1;OPRD1;HTR1D;ADRA2A;HTR1F;HTR1B GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;HTR2A GO:0050796| regulation of insulin secretion ADRA2A;ADRA2C;CNR1 GO:0016032| viral reproduction HTR2A;VDAC1 GO:0033674| positive regulation of kinase activity HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;TRPA1 GO:0007268| synaptic transmission HTR2C;HTR6;HTR1F;HTR1B;GLRB;VDAC1;HTR3A;HTR7;GLRA1;CACNA1G;HTR3E;HTR1E;HTR3B;HTR3D;HTR3C;GLRA3;HTR2A;HTR4;OPRM1;HTR1D;OPRD1 GO:0007565| female pregnancy ADRA2B;ADRA2C;IDO1 GO:0042310| vasoconstriction HTR1D;HTR1A;HTR7;HTR1B;HTR2B GO:0048148| behavioral response to cocaine HTR2A GO:0042428| serotonin metabolic process HTR1A GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1 GO:0071312| cellular response to alkaloid HTR1B;TRPV1 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2C;HTR2A GO:0007507| heart development HTR2B;PPARG GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A GO:0045821| positive regulation of glycolysis HTR2A GO:0045471| response to ethanol HTR1B;HTR3A;OPRM1;HMGCR;SOD1;CNR1;CAT GO:0007202| activation of phospholipase C activity GPR55;HTR2A;HTR2B GO:0014059| regulation of dopamine secretion HTR2A;HTR1B GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;HTR2C;GPR55 GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;ADRA2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR1B;HTR7;HTR6;HTR1F;HTR1E;OPRM1;HTR4;CNR2;OPRD1;HTR1D;CNR1 GO:0034220| ion transmembrane transport HTR3A;GLRB;TRPV1;HTR3E;GLRA1;TRPA1;HTR3B;HTR3D;CHRNA7;GLRA3;HTR3C GO:0071502| cellular response to temperature stimulus HTR2B;HTR1B;TRPV1 GO:0014062| regulation of serotonin secretion HTR1A GO:0042220| response to cocaine HTR3A;HTR1B;SMPD1;OPRM1;CNR1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;ADRA2B;PLA2G1B GO:0008219| cell death HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;HTR2C;HTR2B;ALOX15 GO:0006874| cellular calcium ion homeostasis HTR2C;HTR2B;TRPM8;TRPV4;CHRNA7;GPR12;HTR2A GO:0007210| serotonin receptor signaling pathway HTR2C;HTR2B;HTR2A;HTR1A GO:0042593| glucose homeostasis ADRA2A;TRPV4;PPARG;CNR1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;HTR2B;HTR2C;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1B;HTR7;HTR2C;HTR2B;HTR6;ADRA2A;HTR1F;OPRM1;HTR4;CNR2;OPRD1;HTR1D;GPR55;HTR1A;ADRA2C;ADRA2B;CNR1;GPR12;HTR2A;HTR1E GO:0071363| cellular response to growth factor stimulus TRPV1;HTR3A;CAT;OPRD1 GO:0007568| aging CAT;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2A;HTR2C;HTR2B GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR1B;HTR2A GO:0035640| exploration behavior HTR1A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;HTR2B;HTR2C;HTR1B;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0044380| protein localization to cytoskeleton HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2B;ADRA2A;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0007626| locomotory behavior HTR2C;SOD1;OPRM1 GO:0050795| regulation of behavior HTR1B;HTR2B;HTR1D;HTR1A;HTR2A GO:0007623| circadian rhythm HTR7;AANAT GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A GO:0014824| artery smooth muscle contraction HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;HTR2B;HTR2C 18355:[DB14011 DB00886] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00886|Omapatrilat ACE;MME common genes common pathways GO:0060047| heart contraction SOD1;ACE;GPX1 GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0071345| cellular response to cytokine stimulus MME;TRPV1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1;ACE GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;MME;OPRM1;CNR2;PTGS2;OPRD1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0007283| spermatogenesis ACE;CNR1;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;MME GO:0001822| kidney development MME;CAT;ACE 18356:[DB14011 DB08557] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08557|2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide HSP90AA1 common genes common pathways GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;GPR18;HSP90AA1;PPARG GO:0009409| response to cold TRPM8;PPARG;HSP90AA1;TRPA1 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HSP90AA1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 18357:[DB14011 DB08062] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08062|3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 18358:[DB14011 DB14642] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;ABCC2;VDAC1;TRPV4;CACNA1I;TRPV1 GO:0010628| positive regulation of gene expression TRPV4;AVPR2 GO:0007202| activation of phospholipase C activity AVPR1A;GPR55;HTR2A;AVPR1B GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;AVPR1A;CYP1A2;PTGS2 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;AVPR1A;HTR2A;GPR12;CNR1;AVPR1B;PPARG;GPR18;AVPR2 GO:0006810| transport TRPV2;ABCC1;TRPV1;CACNA1I;ABCC2;ABCG2 GO:0006979| response to oxidative stress ABCC2;PTGS2;SOD1;GPX1;PTGS1;CAT GO:0099133| ABCC2;ABCC1 GO:0051970| negative regulation of transmission of nerve impulse AVPR1A;GLRA1 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCC2;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0014902| myotube differentiation AVPR1A;GPX1 GO:0032496| response to lipopolysaccharide IDO1;ABCC2;CYP1A1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0008284| positive regulation of cell proliferation HTR1A;AVPR1A;HTR2A;PTGS2;HMGCR;CHRNA7;AVPR2 GO:0034097| response to cytokine stimulus PTGS2;AANAT;AVPR2 GO:0045777| positive regulation of blood pressure AVPR2;AVPR1A;CNR1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;AVPR1A GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCC1 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007204| elevation of cytosolic calcium ion concentration AVPR1A;HTR2A;OPRM1;TRPV1;TRPV4;AVPR1B GO:0045907| positive regulation of vasoconstriction AVPR2;AVPR1B;AVPR1A;HTR2A;PTGS2 GO:0032870| cellular response to hormone stimulus AVPR1A;CACNA1H;ABCC2;AVPR2;AVPR1B GO:0051412| response to corticosterone stimulus AVPR1A;AANAT GO:0007165| signal transduction CNR2;OPRM1;OPRD1;AVPR1A;GPR55;HTR1A;GPR12;CNR1;HTR2A;CHRNA7;AVPR1B;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;AVPR2 GO:0007565| female pregnancy IDO1;ABCC2 GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1;ABCC2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;AVPR2 18359:[DB14011 DB04865] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 18360:[DB14011 DB06536] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06536|Tesaglitazar PPARA;PPARG common genes PPARG common pathways GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0043627| response to estrogen stimulus PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0006919| activation of caspase activity PPARG GO:0032868| response to insulin stimulus TRPV4;PPARA;CAT;AANAT GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;PPARA;CNR1;HMGCR GO:1905461| PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;NAAA;GPX1;PTGS1;HMGCR;CYP1A2;PTGS2;PPARA;CYP3A4;NAPEPLD GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG;PPARA GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;PPARA GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;TRPA1 GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0006631| fatty acid metabolic process PTGS1;PPARA;PTGS2;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0030224| monocyte differentiation PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PPARA GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PPARA GO:0045087| innate immune response PPARG GO:0030308| negative regulation of cell growth PPARG GO:0042060| wound healing PPARA;OPRM1;ALOX15 GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG 18361:[DB14011 DB08760] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes PPARG common pathways GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0015909| long-chain fatty acid transport PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0045087| innate immune response PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG 18362:[DB14011 DB12945] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12945|Dihydralazine CYP1A2 common genes CYP1A2 common pathways GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0010468| regulation of gene expression CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 18363:[DB14011 DB04889] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes CYP2D6 common pathways GO:0010628| positive regulation of gene expression TRPV4;SLC6A4 GO:0001666| response to hypoxia DRD2;CYP1A1;CHRNA7;CAT;SLC6A4 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;DRD2 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;SLC6A4;PPARG;CYP1A1;TRPA1 GO:0009416| response to light stimulus DRD2;AANAT GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0050665| hydrogen peroxide biosynthetic process MAOB;CYP1A1;CYP1A2;SOD1 GO:0042220| response to cocaine OPRM1;CNR1;DRD2;SMPD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4;DRD2 GO:0055085| transmembrane transport TRPV2;SLC6A4;CACNA1H;TRPV3;TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;SLC6A2;ABCC1;TRPA1 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;DRD2;TRPV4;TRPM8 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC6A4;GLRA1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;DRD2;PPARG;GPR18 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;DRD2;TRPV1;HTR2A GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;SLC6A4;CAT GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCG2;SLC6A2;ABCC1 GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;DAGLA;CYP2D6;FAAH GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0035094| response to nicotine CNR1;CHRNA7;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0048265| response to pain TRPV1;TRPA1;SLC6A2 GO:0043278| response to morphine DRD2;CNR1;OPRM1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;MAOB GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SLC6A2;SMPD1;ABCC1;MAOB;ABCG2;DRD2;HTR2A;SOD1;CYP1A2;PTGS2;SLC6A4;CAT GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;MAOB;CYP1A1;CYP2C9;CRYZ GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007626| locomotory behavior DRD2;SOD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;DRD2;PPARG GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0007628| adult walking behavior GLRA1;GLRB;DRD2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;MAOB;IDO1 GO:0007623| circadian rhythm SLC6A4;AANAT GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;DRD2;TRPV1;GLRA1;CHRNA7;SLC29A1;GLRA3;OPRM1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0008285| negative regulation of cell proliferation DRD2;CYP1B1;PPARG;PTGS2;OPRM1 GO:0007584| response to nutrient SLC6A4;HMGCR;CNR1;PPARG GO:0010269| response to selenium ion GPX1;MAOB GO:0009636| response to toxin GPX1;CAT;SLC6A4;MAOB;CYP1A1;DRD2;CYP1B1 GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0014854| response to inactivity DRD2;CAT GO:0050482| arachidonic acid secretion DRD2;PLA2G1B GO:1900273| DRD2;CHRNA7 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0007420| brain development ACAT1;SLC6A4 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;PLA2G1B;DRD2;CACNA1I;SMPD1;GPR18;PPARG GO:0001975| response to amphetamine CNR2;SOD1;DRD2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007613| memory SLC6A4;CHRNA7;PTGS2;CNR1;HTR2A GO:0001964| startle response GLRB;DRD2;GLRA1 GO:0008542| visual learning DRD2;HMGCR GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;GLRB;VDAC1;GLRA1;SLC6A2;CACNA1G GO:0048148| behavioral response to cocaine HTR2A;DRD2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0042310| vasoconstriction HTR1A;SLC6A4 GO:0042136| neurotransmitter biosynthetic process SLC6A4;DAGLA GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0001659| temperature homeostasis DRD2;TRPV1;HTR2A;GPX1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0048678| response to axon injury DRD2;SOD1 GO:0051100| negative regulation of binding CYP2D6 GO:0045471| response to ethanol MAOB;DRD2;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0045776| negative regulation of blood pressure CNR1;DRD2 18364:[DB14011 DB07642] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07642|5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 18365:[DB14011 DB14508] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006811| ion transport TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;GRIA3;CACNA1H GO:0007165| signal transduction IMPA1;IMPA2;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0007399| nervous system development GLRB;SMPD1;GSK3B GO:0035556| intracellular signal transduction PLA2G1B;GSK3B GO:0034220| ion transmembrane transport GRIA3;GLRA3;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0048511| rhythmic process PPARG;AANAT;GSK3B GO:0010628| positive regulation of gene expression GSK3B;TRPV4 GO:0006810| transport GRIA3;TRPV2;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;TRPV1;GLRA3;GRIA3;OPRM1;GSK3B;CHRNA7;SLC29A1 GO:0007623| circadian rhythm AANAT;GSK3B GO:0043066| negative regulation of apoptotic process CAT;GSK3B;GPX1;SOD1;PTGS2;HMGCR 18366:[DB14011 DB04187] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways GO:0006749| glutathione metabolic process SOD1;GPX1;GSTM1;GSR GO:0042178| xenobiotic catabolic process GSTM1;CRYZ GO:0008152| metabolic process GSTM1;SMPD1;ACAT1 18367:[DB14011 DB01569] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01569|Formebolone HSD11B2 common genes common pathways GO:0051384| response to glucocorticoid stimulus HSD11B2;PTGS2 GO:0032868| response to insulin stimulus HSD11B2;TRPV4;AANAT;CAT GO:0007565| female pregnancy HSD11B2;IDO1 GO:0006704| glucocorticoid biosynthetic process HSD11B2;CYP17A1 GO:0001666| response to hypoxia HSD11B2;CYP1A1;CHRNA7;CAT GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;HSD11B2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1 GO:0032094| response to food OPRM1;CYP1A1;HSD11B2 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;HSD11B2 18368:[DB14011 DB03414] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03414|5-Thio-a/B-D-Mannopyranosylamine MAN2A1 common genes common pathways GO:0050769| positive regulation of neurogenesis MAN2A1;OPRM1 GO:0008152| metabolic process ACAT1;SMPD1;MAN2A1 GO:0001889| liver development MAN2A1;CYP1A1;ACAT1 18369:[DB14011 DB05434] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0001934| positive regulation of protein phosphorylation CHRNA7;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA;GPX1;HGF GO:0006955| immune response CNR2;OPRD1;CXCL8 GO:0006954| inflammatory response TRPV1;CXCL8;IDO1;ALOX15;PTGS2;CNR2;PTGS1;ALOX5 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A;HGF GO:0007595| lactation SLC29A1;VEGFA GO:0061045| negative regulation of wound healing FGF2;HMGCR GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0001889| liver development ACAT1;CYP1A1;HGF GO:0048469| cell maturation VEGFA;PPARG GO:0001525| angiogenesis VEGFA;PTGS2;FGF2;CYP1B1;CXCL8 GO:0035556| intracellular signal transduction CXCL8;PLA2G1B GO:0007399| nervous system development SMPD1;GLRB;FGF2;VEGFA GO:0008283| cell proliferation HGF;CYP1A1;GPX1;HTR1A GO:0051450| myoblast proliferation HGF;GPX1 GO:0034976| response to endoplasmic reticulum stress CXCL8;ALOX15 GO:0051781| positive regulation of cell division VEGFA;FGF2;CAT GO:0043537| negative regulation of blood vessel endothelial cell migration FGF2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CXCL8;CYP1B1;PPARG GO:0061844| CXCL8;PLA2G1B GO:1902042| GPX1;HGF GO:0090201| negative regulation of release of cytochrome c from mitochondria HGF;GPX1 GO:0043117| positive regulation of vascular permeability VEGFA;TRPV4 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;FGF2;OPRM1;OPRD1;CACNA1I;CXCL8;PLA2G1B;PPARG;GPR18;SMPD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;PPARG GO:0030593| neutrophil chemotaxis PLA2G1B;CXCL8 GO:0030224| monocyte differentiation VEGFA;PPARG GO:0050728| negative regulation of inflammatory response HGF;CNR2 GO:0060326| cell chemotaxis HGF;ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade HGF;FGF2;GPX1 GO:0042060| wound healing OPRM1;FGF2;ALOX15 GO:0030324| lung development CYP1A2;VEGFA GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;VEGFA;PTGS2;CAT;GPX1;HGF GO:0001822| kidney development CAT;VEGFA GO:0008284| positive regulation of cell proliferation HGF;PTGS2;FGF2;VEGFA;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;VEGFA;PPARG;HGF;PLA2G1B GO:0002576| platelet degranulation HGF;SOD1;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;VEGFA GO:0045766| positive regulation of angiogenesis CXCL8;CYP1B1;HGF;CHRNA7;FGF2;VEGFA GO:0001541| ovarian follicle development VEGFA;SOD1 GO:0030855| epithelial cell differentiation PPARG;VDAC1;VEGFA GO:0000187| activation of MAPK activity FGF2;SOD1;CHRNA7;PLA2G1B;HGF GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;FGF2;VEGFA;HMGCR;GPR55;HTR2A GO:0010628| positive regulation of gene expression TRPV4;VEGFA GO:0001666| response to hypoxia CYP1A1;VEGFA;CAT;CHRNA7 GO:0071356| cellular response to tumor necrosis factor TRPV1;CXCL8 GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF2;VEGFA GO:0007186| G-protein coupled receptor signaling pathway CXCL8;PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;HTR2A;FGF2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade HGF;CAT GO:0071456| cellular response to hypoxia PTGS2;VEGFA;OPRD1;SLC29A1 GO:0031100| organ regeneration PPARG;HGF GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA 18370:[DB14011 DB04760] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04760|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways GO:0030282| bone mineralization ALOX15;MMP13;PTGS2 18371:[DB14011 DB06211] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1 GO:0006915| apoptotic process DPEP1;GPX1;VDAC1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;DPEP1;PTGS2 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;DPEP1;ALOX5 GO:0006749| glutathione metabolic process GSR;SOD1;DPEP1;GPX1 GO:0030336| negative regulation of cell migration CYP1B1;DPEP1 GO:0098656| SLC22A8;VDAC1 GO:0006811| ion transport CACNA1H;TRPV3;SLC22A8;GLRA3;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;GPX1;CAT GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;DPEP1;CYP3A7;CYP1A2;CYP3A4 GO:0071277| cellular response to calcium ion DPEP1;ALOX15 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;DPEP1;PTGS2 18372:[DB14011 DB05792] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05792|Arylacenamide SIGMAR1 common genes common pathways GO:0007399| nervous system development GLRB;SMPD1;SIGMAR1 GO:0038003| opioid receptor signaling pathway SIGMAR1;OPRD1;OPRM1 GO:0070207| protein homotrimerization TRPM8;SIGMAR1 GO:0043523| regulation of neuron apoptosis SIGMAR1;GPX1 18373:[DB14011 DB00131] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;PRKAA1 GO:0035094| response to nicotine CNR1;CHRNA7;CREB1 GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4B;PDE4D GO:0006355| regulation of transcription, DNA-dependent HINT1;CREB1;PPARG;PRKAA1 GO:0016236| macroautophagy PRKAB1;PRKAB2;PRKAA1;VDAC1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ADCY1;ABCG2;ACSL1;SMPD1;ABCC1;PPARG;CYP1A1;CREB1;TRPA1 GO:0045893| positive regulation of transcription, DNA-dependent CREB1;PPARG GO:0006631| fatty acid metabolic process PTGS2;PRKAB2;PRKAB1;PTGS1;ACSL1;ALOX15;PRKAA1 GO:0008284| positive regulation of cell proliferation PRKAA1;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process PIM1;PTGS2;HMGCR;SOD1;GPX1;CAT;PRKAA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;FBP1 GO:0043312| neutrophil degranulation CAT;ALOX5;PYGL;APRT GO:0007623| circadian rhythm CREB1;ADCY1;AANAT GO:0008203| cholesterol metabolic process CAT;HMGCR;PRKAA1 GO:0030308| negative regulation of cell growth PPARG;FBP1 GO:0006695| cholesterol biosynthetic process HMGCR;PRKAA1 GO:0010628| positive regulation of gene expression PRKAB1;PRKAA1;TRPV4 GO:0001666| response to hypoxia CHRNA7;CAT;CREB1;CYP1A1;PRKAA1 GO:0006085| acetyl-CoA biosynthetic process ACSS2;ACSS1;ACAT1 GO:0048511| rhythmic process AANAT;PPARG;CREB1;ADCY1;PRKAA1 GO:0031000| response to caffeine PPARG;PRKAA1 GO:0010033| response to organic substance PTGS2;CYP1A2;AMPD1;SOD1;CREB1;CYP1A1;PPARG;TRPA1;ACSL1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;PRKAA1;PLA2G1B GO:0006915| apoptotic process GPX1;HINT1;PIM1;VDAC1 GO:0042593| glucose homeostasis CNR1;TRPV4;PRKAA1;PPARG;PYGL GO:0007186| G-protein coupled receptor signaling pathway PDE4B;ADCY1;PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PDE4D GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;CREB1;TRPV1 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP1B1;PRKAA1;CYP2D6;CYP2C19;CYP3A5;CYP17A1 GO:0071456| cellular response to hypoxia PRKAA1;PTGS2;OPRD1;SLC29A1 GO:0007568| aging PTGS2;HMGCR;PDE4D;NAPEPLD;SOD1;HTR2A;CNR1;CAT;CYP1A1;CREB1 GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPM8;TRPV1;CAT;FBP1 GO:0016032| viral reproduction HTR2A;VDAC1;CREB1 GO:0007595| lactation SLC29A1;CREB1;APRT GO:0042752| regulation of circadian rhythm CREB1;PPARG;PRKAA1;ADCY1 GO:0008542| visual learning HMGCR;CREB1 GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0010629| negative regulation of gene expression CREB1;OPRD1 GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;PRKAA1;TRPA1 GO:0043065| positive regulation of apoptotic process CREB1;PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0016126| sterol biosynthetic process PRKAA1;HMGCR GO:0035556| intracellular signal transduction ADCY1;PLA2G1B GO:0008152| metabolic process FBP1;ACAT1;ACSL1;SMPD1;ACSS2;PYGL;ACSS1 GO:0002027| regulation of heart rate CACNA1G;PDE4D GO:1990090| CREB1;TRPV1 GO:0071361| cellular response to ethanol PRKAA1;GLRA1 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;PRKAA1;TRPV1;ALOX15;DAGLA;ACSL1;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;PRKAB1;PRKAB2 GO:0071294| cellular response to zinc ion CREB1;GLRA1 GO:0071277| cellular response to calcium ion ALOX15;ADCY1 GO:0045821| positive regulation of glycolysis PRKAA1;HTR2A GO:0006351| transcription, DNA-dependent HINT1;CREB1;PPARG;PRKAA1 GO:0071380| cellular response to prostaglandin E stimulus PRKAA1;PPARG GO:0045600| positive regulation of fat cell differentiation CREB1;PPARG;HTR2A GO:0042178| xenobiotic catabolic process CRYZ;ACSL1 GO:0019395| fatty acid oxidation PPARG;PRKAA1 GO:0051291| protein heterooligomerization PRKAA1;GLRB;GLRA1;PRKAB1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;PRKAA1 GO:0007584| response to nutrient ACSL1;PPARG;CNR1;HMGCR GO:0014823| response to activity PRKAA1;CREB1;CAT GO:0008283| cell proliferation GPX1;PIM1;HTR1A;CYP1A1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;ACSL1;CYP1A1;PPARG;TRPA1 GO:0009411| response to UV CAT;PRKAA1 GO:0048643| positive regulation of skeletal muscle tissue development PRKAA1;HMGCR GO:0006939| smooth muscle contraction HTR2A;PDE4D GO:1900273| CHRNA7;CREB1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PRKAA1;PTGS1;PRKAB1;PRKAB2;PTGS2 GO:0007165| signal transduction SMPD1;PPARG;CREB1;GPR18;PRKAA1;PLA2G1B;CACNA1I;ADCY1;PDE4B;OPRM1;CNR2;OPRD1;PDE4D;GPR55;HTR1A;HINT1;HTR2A;GPR12;CNR1;PRKAB1;PRKAB2;CHRNA7 GO:0010332| response to gamma radiation PRKAA1;GPX1 GO:0006641| triglyceride metabolic process ACSL1;CAT;GPX1 GO:0010226| response to lithium ion ADCY1;PTGS2 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;ACSL1;HMGCR;CNR1 GO:0032869| cellular response to insulin stimulus APRT;PPARG;PLA2G1B GO:0007613| memory CREB1;CHRNA7;PTGS2;HTR2A;CNR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY1;OPRM1;OPRD1 18374:[DB14011 DB00594] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0007268| synaptic transmission CACNA1G;ASIC2;GLRA1;GLRB;VDAC1;OPRM1;OPRD1;HTR2A;GLRA3 GO:0009268| response to pH ASIC1;TRPV1 GO:0006816| calcium ion transport CHRNA7;TRPV2;ASIC1;TRPV3;CACNA1H;TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G GO:0035725| sodium ion transmembrane transport CACNA1G;ASIC2;CACNA1I;CACNA1H;SCNN1A;SCNN1B;ASIC1;SCNN1D;SCNN1G GO:0071260| cellular response to mechanical stimulus PTGS2;SLC9A1 GO:0043065| positive regulation of apoptotic process SLC9A1;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A5;CYP1B1;AOC1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCG2 GO:0051930| regulation of sensory perception of pain SLC9A1;OPRM1;OPRD1 GO:0006811| ion transport TRPV2;SCNN1G;CHRNA7;SLC9A1;TRPV3;SLC22A4;SCNN1A;CACNA1H;GLRA3;SCNN1B;ASIC1;SCNN1D;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;SLC22A2;ASIC2;CACNA1G;GLRA1;TRPA1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;SLC9A1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0006812| cation transport ASIC1;SLC9A1;ASIC2;TRPM8;SLC22A2 GO:0050896| response to stimulus SCNN1A;SCNN1D;SCNN1B;SCNN1G;TRPA1;TRPM8 GO:0032869| cellular response to insulin stimulus SLC9A1;PLA2G1B;PPARG GO:0007613| memory CHRNA7;HTR2A;CNR1;ASIC1;PTGS2 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLAU;PLA2G1B;CACNA1I;HTR2A;GPR12;CNR1;ASIC1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7 GO:0006641| triglyceride metabolic process CAT;GPX1;SLC22A4 GO:0070588| calcium ion transmembrane transport CACNA1G;TRPA1;CACNA1I;TRPV4;TRPV1;TRPM8;OPRM1;CACNA1H;TRPV3;ASIC1;TRPV2;CHRNA7 GO:0034765| regulation of ion transmembrane transport CACNA1H;CACNA1I;ASIC2;CACNA1G GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;AOC1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;AOC1 GO:0071407| cellular response to organic cyclic compound SLC9A1;CYP1A1;CYP1B1 GO:0009308| amine metabolic process CYP1A1;AOC1 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0043312| neutrophil degranulation CAT;ALOX5;AOC1;PLAU GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;PPARG;PLA2G1B GO:0046677| response to antibiotic AOC1;CYP1A1;SOD1 GO:0070207| protein homotrimerization TRPM8;ASIC1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;ASIC2 GO:0043066| negative regulation of apoptotic process ASIC2;SOD1;PTGS2;HMGCR;CAT;SLC9A1;GPX1 GO:0055085| transmembrane transport SLC22A2;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G;SLC9A1;TRPV2;SLC22A4;TRPV3;CACNA1H GO:0034220| ion transmembrane transport SCNN1G;CHRNA7;SCNN1A;SLC22A4;SCNN1D;ASIC1;SCNN1B;GLRA3;GLRB;TRPV1;ASIC2;GLRA1;TRPA1 GO:0050891| multicellular organismal water homeostasis TRPV4;SCNN1A;SCNN1B;SCNN1G GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;PLAU GO:0071456| cellular response to hypoxia SLC9A1;SLC29A1;PTGS2;OPRD1 GO:0006810| transport ASIC1;TRPV2;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0071468| cellular response to acidity TRPV1;SLC9A1 GO:0071280| cellular response to copper ion CYP1A1;AOC1;CYP1A2 GO:0007605| sensory perception of sound GPX1;SOD1;ASIC2 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;ASIC2;ASIC1;CACNA1H 18375:[DB14011 DB00569] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0007595| lactation SERPINC1;SLC29A1 GO:0007584| response to nutrient PPARG;CNR1;SERPINC1;HMGCR GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 18376:[DB14011 DB11358] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;FADS1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;FADS2;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0006631| fatty acid metabolic process PTGS2;ELOVL5;PTGS1;FADS1;ALOX15;FADS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;FADS1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG;FADS1 GO:0006633| fatty acid biosynthetic process FADS1;PLA2G1B;FADS2;PTGS2;ELOVL5;PTGS1 GO:0006629| lipid metabolic process FADS1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;FADS2;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;ELOVL5;NAAA;PTGS1;GPX1 18377:[DB14011 DB09205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09205|Moxisylyte ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;BCHE common genes common pathways GO:0007565| female pregnancy ADRA2C;ADRA2B;IDO1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRA1D;CNR1;ADRA1B GO:0035556| intracellular signal transduction PLA2G1B;ADRA1A;ADRA1B GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1D;ADRA1A GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0008285| negative regulation of cell proliferation ADRA1A;CYP1B1;BCHE;PPARG;PTGS2;OPRM1 GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1 GO:0008283| cell proliferation ADRA1D;CYP1A1;GPX1;ADRA1B;HTR1A GO:0045777| positive regulation of blood pressure CNR1;ADRA2B GO:0006939| smooth muscle contraction ADRA1A;HTR2A GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0045907| positive regulation of vasoconstriction ADRA1A;ADRA1D;ADRA1B;HTR2A;ADRA2C;PTGS2 GO:0007165| signal transduction ADRA2A;PLA2G1B;CACNA1I;ADRA1A;PPARG;GPR18;ADRA1D;SMPD1;ADRA1B;CHRNA7;HTR1A;GPR55;ADRA2C;HTR2A;CNR1;GPR12;ADRA2B;OPRM1;CNR2;OPRD1 GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;TRPV4;TRPV1;OPRM1;HTR2A;ADRA1B GO:0050796| regulation of insulin secretion ADRA2A;ADRA2C;CNR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRD1;OPRM1 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;BCHE;ABCG2;ADRA1A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;ADRA1D;ADRA2A GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;ADRA1B;ADRA1D;ADRA1A GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0007202| activation of phospholipase C activity ADRA1A;HTR2A;GPR55 GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;ADRA1A;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0006915| apoptotic process GPX1;ADRA1A;VDAC1 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;ADRA2B;SOD1 GO:0042593| glucose homeostasis ADRA2A;TRPV4;PPARG;ADRA1B;CNR1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;ADRA2C;ADRA2B;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;ADRA1B;PPARG;GPR18;ADRA1D;ADRA2A;ADRA1A GO:0007568| aging CYP1A1;ADRA1A;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT 18378:[DB14011 DB03059] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03059|Acetoacetyl-CoA HADH;ACADS;ECHS1 common genes common pathways GO:0006635| fatty acid beta-oxidation ECHS1;HADH;ACAT1;ACADS GO:0006631| fatty acid metabolic process ALOX15;ECHS1;HADH;PTGS2;ACADS;PTGS1 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;HADH;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;ACADS;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;HADH;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0009725| response to hormone stimulus ACAT1;HADH GO:0032868| response to insulin stimulus TRPV4;HADH;AANAT;CAT GO:0014823| response to activity CAT;HADH GO:0008152| metabolic process ECHS1;SMPD1;ACADS;ACAT1 GO:0006629| lipid metabolic process ECHS1;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;ACADS;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HADH;HMGCR;PTGS2;CYP1A2 18379:[DB14011 DB04066] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways GO:0006693| prostaglandin metabolic process PTGS1;PTGR1;PTGS2 GO:0006691| leukotriene metabolic process PTGR1;ALOX5;ABCC1;ALOX15 GO:0055114| oxidation-reduction process CAT;PTGR1;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP1A1;CYP2C9;CRYZ 18380:[DB14011 DB09282] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0007165| signal transduction PPARG;GPR18;GUCY1A2;PDE5A;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0035556| intracellular signal transduction GUCY1A2;PLA2G1B GO:0008152| metabolic process SMPD1;PDE5A;ACAT1 GO:0042130| negative regulation of T cell proliferation IDO1;PDE5A GO:0043406| positive regulation of MAP kinase activity HTR2A;PDE5A 18381:[DB14011 DB00630] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0006811| ion transport TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;ATP6V1A;CHRNA7;TRPV3;CACNA1H;GLRA3 GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;PTGS1;GPX1;FDPS;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0006879| cellular iron ion homeostasis ABCG2;ATP6V1A;SOD1 GO:0016032| viral reproduction FDPS;HTR2A;VDAC1 GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;ATP6V1A GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9;FDPS;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0045540| regulation of cholesterol biosynthetic process FDPS;HMGCR GO:0008299| isoprenoid biosynthetic process FDPS;HMGCR GO:0034220| ion transmembrane transport GLRB;TRPV1;GLRA1;TRPA1;ATP6V1A;CHRNA7;GLRA3 GO:0010977| negative regulation of neuron projection development TRPV4;PTPRS GO:0006695| cholesterol biosynthetic process FDPS;HMGCR GO:0008203| cholesterol metabolic process CAT;FDPS;HMGCR GO:0007155| cell adhesion PTPRS;CYP1B1 GO:0006694| steroid biosynthetic process CYP17A1;FDPS;HMGCR 18382:[DB14011 DB02616] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02616|FR117016 ADA common genes common pathways GO:0001889| liver development ACAT1;ADA;CYP1A1 GO:0042542| response to hydrogen peroxide SOD1;GPX1;ADA;CAT;TRPA1 GO:0001890| placenta development ADA;SOD1;PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0030324| lung development CYP1A2;ADA GO:0033197| response to vitamin E ADA;CAT GO:0007155| cell adhesion ADA;CYP1B1 GO:0043066| negative regulation of apoptotic process ADA;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT;ADA GO:0043278| response to morphine OPRM1;CNR1;ADA GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0007568| aging CYP1A1;ADA;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;ADA 18383:[DB14011 DB06098] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06098|PRLX 93936 VDAC2;VDAC3 common genes common pathways GO:0006820| anion transport VDAC2;GLRA1;VDAC1 GO:0055085| transmembrane transport TRPV3;CACNA1H;VDAC2;VDAC3;TRPV2;ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2 GO:0007612| learning VDAC3;PTGS2;VDAC1 GO:0098656| VDAC1;VDAC2;VDAC3 GO:0001662| behavioral fear response HTR1A;VDAC3;VDAC1 GO:0007270| neuron-neuron synaptic transmission VDAC3;VDAC1 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;VDAC2;VDAC3;CHRNA7 GO:0007268| synaptic transmission CACNA1G;GLRA1;GLRB;VDAC1;OPRD1;OPRM1;GLRA3;HTR2A;VDAC3 18384:[DB14011 DB08326] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways GO:0051384| response to glucocorticoid stimulus ACSBG1;PTGS2 GO:0008152| metabolic process ACSBG1;ACAT1;SMPD1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;ACSBG1;NAAA;PTGS1;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0006631| fatty acid metabolic process ACSBG1;PTGS2;PTGS1;ALOX15 18385:[DB14011 DB08846] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes CYP1A1 common pathways GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0006641| triglyceride metabolic process GPX1;CAT;CYP2E1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;CSNK2A1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PRKCB;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0043010| camera-type eye development CYP1A1 GO:0032502| developmental process CYP1A1 GO:0050796| regulation of insulin secretion PRKCA;CNR1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:1900087| CYP1A1 GO:0098656| VDAC1;SLC22A6 GO:0070365| hepatocyte differentiation CYP1A1 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0017143| insecticide metabolic process CYP1A1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;SQLE;CYP1A2 GO:0009624| response to nematode CYP1A1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1 GO:0006811| ion transport TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;GLRA1;TRPA1;CACNA1G;SLC22A11;CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3 GO:0008283| cell proliferation SYK;CYP1A1;HTR1A;GPX1 GO:0042953| lipoprotein transport PRKCB;PPARG GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0035556| intracellular signal transduction SYK;PLA2G1B;PRKCA;PRKCB GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0016126| sterol biosynthetic process HMGCR;SQLE GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1;PRKCB GO:0070988| demethylation CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0045471| response to ethanol CAT;OPRM1;HMGCR;CA3;CYP2E1;CNR1;SOD1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;SYK GO:0001525| angiogenesis SYK;PRKCA;CYP1B1;PTGS2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0009692| ethylene metabolic process CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;PPARG GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0048565| digestive tract development CYP1A1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SYK;HTR2A GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;CACNA1H;TRPV3;CHRNA7;PRKCB;TRPV2 GO:0016032| viral reproduction SYK;VDAC1;HTR2A GO:0060137| maternal process involved in parturition CYP1A1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;PRKCB;CAT GO:0006954| inflammatory response SYK;IDO1;ALOX15;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2;GPX1 GO:0046415| urate metabolic process SLC22A11;ABCG2 GO:0019370| leukotriene biosynthetic process ALOX5;SYK;PLA2G1B GO:0009635| response to herbicide CYP1A1 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;PRKCB;CHRNA7;HTR2A;GPR12 GO:0006979| response to oxidative stress PTGS2;CA3;SOD1;GPX1;PTGS1;CAT GO:0010041| response to iron(III) ion CYP1A1 GO:0002376| immune system process IDO1;SYK;PRKCB GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0007568| aging CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1 GO:0048514| blood vessel morphogenesis SYK;CYP1B1 GO:0034605| cellular response to heat PTGS2;PRKACA;TRPV4;TRPV1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0009611| response to wounding GPX1;CYP1A1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CA2;CYP1A2;PTGS2;SOD1;SQLE GO:0048511| rhythmic process AANAT;CSNK2A1;PPARG GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CAT;CHRNA7;CA9;PRKCB;CYP1A1 GO:0010193| response to ozone CAT;CYP2E1 GO:0000187| activation of MAPK activity SYK;PLA2G1B;SOD1;CHRNA7 GO:0006915| apoptotic process CSNK2A1;GPX1;PRKCB;PRKCA;VDAC1 GO:0045766| positive regulation of angiogenesis PRKCB;CHRNA7;CYP1B1;PRKCA GO:0045540| regulation of cholesterol biosynthetic process SQLE;HMGCR GO:0055085| transmembrane transport SLC22A11;TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;SLC22A6;CACNA1G;ABCC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;PRKCA;TRPV4 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0045087| innate immune response PPARG;SYK GO:0007155| cell adhesion PRKCA;CYP1B1 GO:0001822| kidney development CAT;CA2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;CSNK2A1;PTGS2;CHRNA7 GO:0009615| response to virus CYP1A1 GO:0006695| cholesterol biosynthetic process SQLE;HMGCR GO:0071333| cellular response to glucose stimulus SLC29A1;PRKACA GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0008203| cholesterol metabolic process SQLE;CAT;HMGCR GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;CYP1A1;IDO1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;SYK GO:0009308| amine metabolic process CYP1A1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 GO:0055114| oxidation-reduction process CAT;SQLE;PTGS1;ALOX5;GPX1;SOD1;CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;CA9;CAT;CYP1A2;PTGS2;CYP2E1;SOD1;HTR2A GO:0046685| response to arsenic-containing substance CYP1A1 GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CSNK2A1;PRKCB GO:0030593| neutrophil chemotaxis PLA2G1B;SYK 18386:[DB14011 DB03349] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HINT1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CACNA1I;PLA2G1B;PDE4B;SMPD1;PPARG;GPR18 GO:0006351| transcription, DNA-dependent PPARG;HINT1 GO:0006915| apoptotic process VDAC1;GPX1;HINT1 GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;PDE4B;GPR18;PPARG GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4B GO:0006355| regulation of transcription, DNA-dependent HINT1;PPARG 18387:[DB14011 DB02872] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways GO:0042220| response to cocaine SMPD1;MDM2;OPRM1;CNR1 GO:0010977| negative regulation of neuron projection development TRPV4;MDM2 GO:0010628| positive regulation of gene expression MDM2;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;MDM2 GO:0071363| cellular response to growth factor stimulus MDM2;TRPV1;OPRD1;CAT GO:0010468| regulation of gene expression CYP1A2;MDM2 GO:0071456| cellular response to hypoxia MDM2;PTGS2;OPRD1;SLC29A1 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;MDM2;SMPD1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;MDM2 GO:0043278| response to morphine MDM2;OPRM1;CNR1 GO:0008284| positive regulation of cell proliferation MDM2;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0046677| response to antibiotic CYP1A1;MDM2;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;MDM2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;MDM2;TRPV1;TRPV4 GO:0009636| response to toxin MDM2;CYP1A1;CYP1B1;GPX1;CAT GO:0070301| cellular response to hydrogen peroxide MDM2;CYP1B1 GO:0010629| negative regulation of gene expression MDM2;OPRD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;MDM2 GO:0016032| viral reproduction MDM2;VDAC1;HTR2A GO:0071312| cellular response to alkaloid TRPV1;MDM2 GO:0002027| regulation of heart rate MDM2;CACNA1G GO:0007507| heart development MDM2;PPARG 18388:[DB14011 DB08822] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08822|Azilsartan medoxomil AGTR1 common genes common pathways GO:0060326| cell chemotaxis ABCC1;AGTR1 GO:0042127| regulation of cell proliferation AGTR1;PTGS1;PTGS2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGTR1;OPRM1;OPRD1;HTR2A GO:0001822| kidney development AGTR1;CAT GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;AGTR1;GPR18 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;AGTR1 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0050729| positive regulation of inflammatory response AGTR1;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;AGTR1;CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 18389:[DB14011 DB02837] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02837|O4-Sulfonylgalactose MBL2 common genes common pathways GO:0002376| immune system process IDO1;MBL2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1;MBL2 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;MBL2 GO:0045087| innate immune response MBL2;PPARG 18390:[DB14011 DB05418] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05418|GW 597599 TACR1 common genes common pathways GO:0048266| behavioral response to pain TRPV1;TACR1 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;TACR1;CNR1;SOD1 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRM1;CNR2;PTGS2;TACR1;OPRD1 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;TACR1;OPRM1;OPRD1;GLRA3;HTR2A GO:0009408| response to heat TRPV1;TRPV2;SOD1;TRPV3;TACR1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;CNR2;PTGS2;TACR1;ALOX5;PTGS1 GO:0060083| smooth muscle contraction involved in micturition TACR1;TRPV1 GO:0043117| positive regulation of vascular permeability TACR1;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;TACR1;OPRM1;HTR2A GO:0045907| positive regulation of vasoconstriction TACR1;PTGS2;HTR2A GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;TACR1;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0009725| response to hormone stimulus TACR1;ACAT1 GO:0042755| eating behavior OPRD1;TACR1;OPRM1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;TACR1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0045777| positive regulation of blood pressure TACR1;CNR1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TACR1 GO:0008217| regulation of blood pressure PTGS2;TACR1;SOD1;PTGS1;PPARG GO:0007611| learning or memory CHRNA7;TACR1;CNR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;TACR1;OPRM1 GO:0043278| response to morphine TACR1;OPRM1;CNR1 GO:0048265| response to pain TACR1;TRPV1;TRPA1 GO:0035094| response to nicotine CHRNA7;CNR1;TACR1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;TACR1;CAT GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;GPR12;CNR1;HTR2A;TACR1;CNR2;OPRM1;OPRD1 GO:0010193| response to ozone CAT;TACR1 18391:[DB14011 DB05218] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05218|PN0621 TNF common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0006955| immune response OPRD1;CNR2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;PLA2G1B;CAT GO:0006954| inflammatory response TNF;TRPV1;IDO1;ALOX15;PTGS2;CNR2;PTGS1;ALOX5 GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;TNF;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation TNF;PTGS2;CNR1 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0006919| activation of caspase activity PPARG;TNF GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;TNF GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0050796| regulation of insulin secretion CNR1;TNF GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2;HMGCR GO:0071407| cellular response to organic cyclic compound CYP1B1;TNF;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;TNF GO:0009615| response to virus TNF;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TNF;PPARG GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0042127| regulation of cell proliferation PTGS2;PTGS1;TNF GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1;TNF GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0010628| positive regulation of gene expression TRPV4;TNF GO:0000187| activation of MAPK activity PLA2G1B;TNF;CHRNA7;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TNF;TRPV4;ALOX15 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TRPV1;PTGS2;OPRM1 18392:[DB14011 DB07976] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0007565| female pregnancy DHODH;IDO1 GO:0007595| lactation DHODH;SLC29A1 GO:0043065| positive regulation of apoptotic process DHODH;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0014070| response to organic cyclic compound DHODH;AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;DHODH;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;DHODH;CAT GO:0042594| response to starvation ACAT1;DHODH;PPARG GO:0031000| response to caffeine DHODH;PPARG 18393:[DB14011 DB03791] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03791|(3-{3-[[2-Chloro-3-(Trifluoromethyl)Benzyl](2,2-Diphenylethyl)Amino]Propoxy}Phenyl)Acetic Acid NR1H2 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;NR1H2 GO:0006351| transcription, DNA-dependent NR1H2;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1H2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter NR1H2;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;NR1H2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;NR1H2 GO:0055088| lipid homeostasis NR1H2;PPARG GO:0010887| negative regulation of cholesterol storage PPARG;NR1H2 GO:0045893| positive regulation of transcription, DNA-dependent NR1H2;PPARG GO:0006355| regulation of transcription, DNA-dependent NR1H2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1H2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;NR1H2;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1H2;PLA2G1B GO:0045892| negative regulation of transcription, DNA-dependent NR1H2;PPARG GO:0010628| positive regulation of gene expression TRPV4;NR1H2 18394:[DB14011 DB02499] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02499|Dinor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0046686| response to cadmium ion CAT;ARG1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ARG1 GO:0042130| negative regulation of T cell proliferation ARG1;IDO1 GO:0007568| aging CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT;ARG1 GO:0009611| response to wounding CYP1A1;ARG1;GPX1 GO:0002376| immune system process ARG1;IDO1 GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;ARG1;HTR2A;SOD1;PTGS2;CYP1A2 GO:0033189| response to vitamin A ARG1;CAT;CYP1A1;PPARG GO:0010042| response to manganese ion ARG1;PTGS2 GO:0030324| lung development CYP1A2;ARG1 GO:0032496| response to lipopolysaccharide ARG1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;CYP1A1 GO:0033197| response to vitamin E CAT;ARG1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0045087| innate immune response ARG1;PPARG GO:0043312| neutrophil degranulation ALOX5;ARG1;CAT GO:0070207| protein homotrimerization ARG1;TRPM8 GO:0010269| response to selenium ion ARG1;GPX1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ARG1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway ARG1;PPARG GO:0010043| response to zinc ion ARG1;AANAT GO:0043434| response to peptide hormone stimulus ARG1;TRPV1 GO:0007565| female pregnancy IDO1;ARG1 GO:0009635| response to herbicide ARG1;CYP1A1 GO:0001889| liver development CYP1A1;ACAT1;ARG1 GO:0048678| response to axon injury SOD1;ARG1 18395:[DB14011 DB00276] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0002576| platelet degranulation SOD1;ALB;ORM1 GO:0043066| negative regulation of apoptotic process ALB;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT;ORM1 GO:0048511| rhythmic process TOP2A;PPARG;AANAT GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;ABCB1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1H;KCNH2;TRPV3;TRPV2 GO:0032720| negative regulation of tumor necrosis factor production ORM1;GPR18;CHRNA7 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;GLRB;CACNA1G;GLRA1 GO:0098869| ALB;GSR;GPX1;PTGS1;CAT;PTGS2 GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCB1;ABCG2;ABCC1 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;ORM1;TRPV1;ALOX15;IDO1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0086010| KCNH2;CACNA1H;CACNA1G;CACNA1I GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;TOP2A;PPARG;PTGS2;CNR1;SOD1 GO:0086091| KCNH2;CACNA1G GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;KCNH2;CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0001895| retina homeostasis ALB;SOD1 GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;KCNH2;CACNA1H GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 18396:[DB14011 DB02109] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02109|Hadacidin purA;ADSSL1 common genes common pathways GO:0042594| response to starvation PPARG;ADSSL1;ACAT1 GO:0002376| immune system process ADSSL1;IDO1 18397:[DB14011 DB03415] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;ACADM;CYP2C9;PPARG;GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4 GO:0008152| metabolic process SMPD1;ACADM;ACAT1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;ACADM;CNR1;HMGCR GO:0006635| fatty acid beta-oxidation ACADM;ACAT1 GO:0055114| oxidation-reduction process ACADM;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ACADM;ALOX15 18398:[DB14011 DB05408] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05408|Emricasan CASP1;CASP3;CASP7 common genes common pathways GO:0045165| cell fate commitment PPARG;CASP3 GO:0007507| heart development PPARG;CASP3 GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0042542| response to hydrogen peroxide TRPA1;CAT;CASP3;GPX1;SOD1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1;CASP3 GO:0050727| regulation of inflammatory response CASP1;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CASP3;AANAT;ACAT1;PTGS2;CYP1A2 GO:0006919| activation of caspase activity CASP3;PPARG;CASP1 GO:0009411| response to UV CAT;CASP3 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;CASP1;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;CASP3;HTR2A;SOD1;CYP1A2;PTGS2 GO:0071407| cellular response to organic cyclic compound CASP3;CYP1A1;CYP1B1 GO:0035094| response to nicotine CASP3;CHRNA7;CNR1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CASP3;CYP1A1;CASP1;IDO1 GO:0042060| wound healing ALOX15;OPRM1;CASP3 GO:0007611| learning or memory CNR1;CASP3;CHRNA7 GO:0046677| response to antibiotic CYP1A1;CASP3;SOD1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;CASP3;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0006915| apoptotic process VDAC1;CASP1;CASP7;CASP3;GPX1 GO:0043200| response to amino acid stimulus GLRB;CASP3;GLRA3 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CASP3;SOD1;PTGS2;CYP1A2 GO:0001666| response to hypoxia CYP1A1;CASP1;CASP3;CAT;CHRNA7 GO:0009611| response to wounding CYP1A1;GPX1;CASP3 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;CASP3 GO:0007605| sensory perception of sound SOD1;CASP3;GPX1 18399:[DB14011 DB06999] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways GO:0007165| signal transduction HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;BRAF;PLA2G1B;CACNA1I GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;BRAF GO:0043434| response to peptide hormone stimulus TRPV1;BRAF GO:0051291| protein heterooligomerization BRAF;GLRB;GLRA1 GO:1990090| TRPV1;BRAF GO:0035556| intracellular signal transduction BRAF;PLA2G1B GO:0071277| cellular response to calcium ion BRAF;ALOX15 GO:0008542| visual learning HMGCR;BRAF GO:0043524| negative regulation of neuron apoptosis BRAF;SOD1 GO:0048538| thymus development BRAF;SOD1 GO:0015758| glucose transport BRAF;PLA2G1B GO:0010628| positive regulation of gene expression TRPV4;BRAF GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;BRAF;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;CHRNA7 GO:0051591| response to cAMP AANAT;BRAF GO:0043066| negative regulation of apoptotic process BRAF;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;BRAF 18400:[DB14011 DB07435] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07435|1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE POLK;polA common genes common pathways GO:0034644| cellular response to UV POLK;PTGS2 18401:[DB14011 DB14018] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14018|Bromotheophylline CYP1A2 common genes CYP1A2 common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG;GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;ACAT1;AANAT GO:0045333| cellular respiration CYP1A2 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0032259| methylation CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;IDO1;CYP1A1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 18402:[DB14011 DB03240] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03240|(S)-2-Amino-3-(1,3,5,7-Pentahydro-2,4-Dioxo-Cyclopenta[E]Pyrimidin-1-Yl) Proionic Acid GRIA2 common genes common pathways GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GRIA2;GLRA1;TRPA1;TRPV1;GLRB GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;GRIA2;SLC29A1;CHRNA7;GLRA1;GLRB;TRPV1 GO:0006811| ion transport CHRNA7;GRIA2;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;GLRA1;TRPA1;CACNA1G GO:0007165| signal transduction GRIA2;CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0007268| synaptic transmission VDAC1;GLRB;CACNA1G;GLRA1;GRIA2;OPRD1;OPRM1;HTR2A;GLRA3 18403:[DB14011 DB04883] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04883|Darusentan EDNRA common genes common pathways GO:0015758| glucose transport EDNRA;PLA2G1B GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EDNRA GO:0001666| response to hypoxia CHRNA7;CAT;EDNRA;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG;EDNRA GO:0014824| artery smooth muscle contraction EDNRA;HTR2A GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;EDNRA GO:0008283| cell proliferation GPX1;HTR1A;EDNRA;CYP1A1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;EDNRA;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0006939| smooth muscle contraction EDNRA;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDNRA;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration EDNRA;TRPV1;TRPV4;OPRM1;HTR2A GO:0007507| heart development EDNRA;PPARG GO:0042310| vasoconstriction HTR1A;EDNRA 18404:[DB14011 DB00878] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00878|Chlorhexidine HNMT;cat common genes common pathways GO:0032259| methylation CYP1A2;HNMT GO:0007420| brain development ACAT1;HNMT 18405:[DB14011 DB09265] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09265|Lixisenatide GLP1R common genes common pathways GO:0008016| regulation of heart contraction CACNA1H;GLP1R GO:0007166| cell surface receptor linked signaling pathway TRPA1;GLP1R;TRPV1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;SMPD1;GLP1R;GPR18;PPARG;PLA2G1B;CACNA1I GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;TRPV4;TRPV1;OPRM1;HTR2A GO:0050796| regulation of insulin secretion GLP1R;CNR1 GO:0045777| positive regulation of blood pressure CNR1;GLP1R GO:0007611| learning or memory GLP1R;CNR1;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GLP1R;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 18406:[DB14011 DB07621] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP2A6;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP2A6;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP2A6;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP2A6;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP2A6;CYP3A4 18407:[DB14011 DB11429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11429|Mibolerone AR common genes common pathways GO:0007165| signal transduction CHRNA7;AR;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;OPRM1;PTGS2 GO:0008283| cell proliferation CYP1A1;GPX1;AR;HTR1A GO:0007548| sex differentiation CYP17A1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport TRPV2;AR;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR 18408:[DB14011 DB08305] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08305|(3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide GRIA2 common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GRIA2 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;GRIA2;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;GRIA2;OPRM1;OPRD1;GLRA3;HTR2A GO:0034220| ion transmembrane transport GRIA2;CHRNA7;GLRA3;TRPV1;GLRB;TRPA1;GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;SLC29A1;GRIA2;CHRNA7;OPRM1;GLRA3 18409:[DB14011 DB05466] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05466|R673 TACR1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;TACR1;OPRD1;HTR2A GO:0007611| learning or memory CHRNA7;TACR1;CNR1 GO:0035094| response to nicotine TACR1;CNR1;CHRNA7 GO:0048265| response to pain TRPV1;TRPA1;TACR1 GO:0043278| response to morphine OPRM1;TACR1;CNR1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;TACR1;CNR2;OPRD1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;TACR1;CAT GO:0010193| response to ozone TACR1;CAT GO:0045471| response to ethanol CNR1;SOD1;TACR1;OPRM1;HMGCR;CAT GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR1;HTR2A;OPRD1;TACR1;PTGS2;CNR2;OPRM1 GO:0048266| behavioral response to pain TACR1;TRPV1 GO:0007268| synaptic transmission TACR1;OPRM1;OPRD1;GLRA3;HTR2A;GLRB;VDAC1;CACNA1G;GLRA1 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS1;ALOX5;PTGS2;CNR2;TACR1 GO:0009408| response to heat TRPV2;SOD1;TACR1;TRPV3;TRPV1 GO:0043117| positive regulation of vascular permeability TACR1;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;TACR1;HTR2A;TRPV1;TRPV4 GO:0060083| smooth muscle contraction involved in micturition TACR1;TRPV1 GO:0009725| response to hormone stimulus TACR1;ACAT1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;TACR1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7 GO:0045907| positive regulation of vasoconstriction PTGS2;TACR1;HTR2A GO:0045777| positive regulation of blood pressure CNR1;TACR1 GO:0042755| eating behavior OPRD1;TACR1;OPRM1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;TACR1;PTGS2;AANAT;ACAT1 GO:0008217| regulation of blood pressure SOD1;TACR1;PTGS2;PTGS1;PPARG GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 18410:[DB14011 DB05752] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;CHRM1;HTR2A GO:0009615| response to virus CYP1A1;CHRM2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;CNR1;CNR2;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CHRM3;PPARG;GPR18;CHRM4;CHRM5;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CHRM1;GPR12;CNR1;HTR2A;CHRM2 GO:0019226| transmission of nerve impulse SOD1;CHRM5 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CHRM2;CNR1 GO:0007399| nervous system development GLRB;CHRM3;SMPD1;CHRM1;CHRM2 GO:0008016| regulation of heart contraction CACNA1H;CHRM2 GO:0007166| cell surface receptor linked signaling pathway CHRM4;TRPV1;TRPA1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008283| cell proliferation CHRM4;CHRM3;CYP1A1;GPX1;CHRM5;HTR1A;CHRM1 GO:0006939| smooth muscle contraction CHRM3;HTR2A GO:0007165| signal transduction PLA2G1B;CACNA1I;CHRM4;PPARG;GPR18;SMPD1;CHRM3;CHRNA7;HTR1A;GPR55;CHRM1;GPR12;CNR1;HTR2A;CHRM2;OPRM1;CHRM5;CNR2;OPRD1 GO:0050890| cognition CHRM1;CHRNA7 18411:[DB14011 DB07804] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07804|5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 18412:[DB14011 DB04805] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04805|Virginiamycin S1 RPL37 common genes common pathways 18413:[DB14011 DB06460] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways GO:0001666| response to hypoxia CYP1A1;EDNRA;CAT;CHRNA7 GO:0007202| activation of phospholipase C activity EDNRA;HTR2A;GPR55 GO:0015758| glucose transport PLA2G1B;EDNRA GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;EDNRB;PPARG;EDNRA;GPR18 GO:0007568| aging EDNRB;CYP1A1;CAT;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2 GO:0048265| response to pain TRPA1;TRPV1;EDNRB GO:0042311| vasodilation GPX1;EDNRB GO:0043066| negative regulation of apoptotic process EDNRB;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation EDNRB;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;EDNRB GO:0032496| response to lipopolysaccharide EDNRB;IDO1;CYP1A1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0014824| artery smooth muscle contraction HTR2A;EDNRA GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;EDNRB GO:0008217| regulation of blood pressure EDNRA;PPARG;EDNRB;PTGS2;SOD1;PTGS1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;EDNRB;PTGS2;CYP1A2;ACAT1;AANAT GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;EDNRB GO:0008283| cell proliferation EDNRA;CYP1A1;HTR1A;GPX1 GO:0006939| smooth muscle contraction HTR2A;EDNRA GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CACNA1I;PLA2G1B;EDNRB;SMPD1;EDNRA;PPARG;GPR18 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDNRA;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;EDNRA;EDNRB;TRPV4;TRPV1 GO:0001934| positive regulation of protein phosphorylation EDNRB;CHRNA7 GO:0042310| vasoconstriction HTR1A;EDNRA;EDNRB GO:0007507| heart development EDNRA;PPARG GO:0007399| nervous system development EDNRB;GLRB;SMPD1 GO:0007194| negative regulation of adenylate cyclase activity EDNRB;OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPV1;EDNRB;TRPA1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;EDNRB 18414:[DB14011 DB07742] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07742|N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE CA2 common genes common pathways GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CA2;SOD1;PTGS2;CYP1A2 GO:0001822| kidney development CAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 18415:[DB14011 DB02535] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02535|Aminodi(Ethyloxy)Ethylaminocarbonylbenzenesulfonamide CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 18416:[DB14011 DB01019] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CHRM4;GPR18;PPARG;CHRM3;CHRM2;GPR12;CNR1;HTR2A;CHRM1;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;CNR1;CNR2;OPRM1;OPRD1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;CHRM1;HTR1A;HTR2A;CHRNA7 GO:0009615| response to virus CHRM2;CYP1A1 GO:0007165| signal transduction CHRM4;CACNA1I;PLA2G1B;CHRM3;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;CHRM2;HTR2A;CNR1;GPR12;CHRM1;HTR1A;GPR55 GO:0006939| smooth muscle contraction CHRM3;HTR2A GO:0050890| cognition CHRM1;CHRNA7 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0008283| cell proliferation HTR1A;CHRM1;GPX1;CYP1A1;CHRM3;CHRM4 GO:0007399| nervous system development CHRM1;CHRM2;CHRM3;SMPD1;GLRB GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CHRM2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;CHRM4 GO:0008016| regulation of heart contraction CHRM2;CACNA1H 18417:[DB14011 DB13800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0009408| response to heat TRPV1;TRPV2;CASQ1;SOD1;TRPV3 GO:0002027| regulation of heart rate CALM1;CACNA1G GO:0051592| response to calcium ion AANAT;CALM1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;CASQ1;SOD1 GO:0055085| transmembrane transport CALM1;TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;CASQ1;GLRA3;CHRNA7 GO:0006936| muscle contraction GLRA1;CALM1;CACNA1H GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CALM1;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0035307| positive regulation of protein dephosphorylation SMPD1;CALM1 GO:0002576| platelet degranulation SOD1;CALM1 18418:[DB14011 DB03337] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03337|1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18419:[DB14011 DB04527] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways GO:0045087| innate immune response MASP2;PPARG GO:0002376| immune system process MASP2;IDO1 18420:[DB14011 DB08491] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08491|N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE MMP1 common genes common pathways GO:0016032| viral reproduction MMP1;HTR2A;VDAC1 18421:[DB14011 DB08613] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0006954| inflammatory response HDAC4;TRPV1;IDO1;ALOX15;CNR2;PTGS2;PTGS1;ALOX5 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;PPARG GO:0007399| nervous system development HDAC4;SMPD1;GLRB GO:0071260| cellular response to mechanical stimulus PTGS2;HDAC4 GO:0006351| transcription, DNA-dependent PPARG;HDAC4 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;HDAC4;OPRM1;PTGS2 GO:0040029| regulation of gene expression, epigenetic GPX1;HDAC4 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;HDAC4 GO:0006355| regulation of transcription, DNA-dependent HDAC4;PPARG GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;HDAC4;PPARG;CYP1A1;TRPA1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;HDAC4 GO:0008284| positive regulation of cell proliferation HDAC4;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;HDAC4;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;HDAC4 GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC4 GO:0045892| negative regulation of transcription, DNA-dependent HDAC4;PPARG 18422:[DB14011 DB03024] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03024|2-Methyl-3-(2-Aminothiazolo)Propanal REN common genes common pathways GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;REN;CYP1A1;PPARG GO:0051591| response to cAMP REN;AANAT GO:0001822| kidney development CAT;REN GO:0035902| response to immobilization stress CYP1A2;REN;PPARG;CYP1A1 GO:0032496| response to lipopolysaccharide IDO1;REN;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;REN;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0008217| regulation of blood pressure REN;PPARG;PTGS1;PTGS2;SOD1 GO:0048469| cell maturation REN;PPARG 18423:[DB14011 DB01496] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes CHRNA7 common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902004| CHRNA7 GO:0007268| synaptic transmission CACNA1G;GABRA5;GLRA1;GLRB;VDAC1;OPRM1;OPRD1;GRIK2;GLRA3;HTR2A;GRIA2;CHRNA4 GO:0043524| negative regulation of neuron apoptosis GRIK2;SOD1;GABRA5 GO:1902476| GLRA3;GABRA1;GABRA6;GABRA4;GLRA1;GABRA3;GABRA5;GABRA2;GLRB GO:0006816| calcium ion transport TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;CHRNA4;TRPV2;CHRNA7;TRPV3;CACNA1H GO:1902430| CHRNA7 GO:0019228| regulation of action potential in neuron CACNA1G;CACNA1I;GRIK2;CACNA1H GO:0019233| sensory perception of pain TRPV1;TRPA1;CHRNA4;OPRD1;CNR2;PTGS2;OPRM1;HTR2A;CNR1 GO:0060078| regulation of postsynaptic membrane potential GABRA1;CHRNA7 GO:0006811| ion transport TRPV2;GRIA2;CHRNA4;CHRNA7;TRPV3;CACNA1H;GABRA1;GLRA3;GABRA4;GABRA6;GRIK2;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;GABRA2;GABRA5;GABRA3;CACNA1G;GLRA1;TRPA1 GO:0001662| behavioral fear response HTR1A;GRIK2;VDAC1;GABRA5 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0050890| cognition CHRNA4;CHRNA7 GO:0007420| brain development ACAT1;GABRA5 GO:0007165| signal transduction PPARG;GPR18;SMPD1;GABRA5;CACNA1I;PLA2G1B;GPR55;GABRA6;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7;CHRNA4;GRIA2 GO:1900273| CHRNA7 GO:1904645| CHRNA7 GO:0006821| chloride transport GABRA4;GABRA6;GABRA1;GLRA3;GLRA1;GABRA3;GABRA5;GABRA2;GLRB GO:0070588| calcium ion transmembrane transport TRPM8;TRPV1;CACNA1I;TRPV4;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;OPRM1;TRPV3 GO:0050808| synapse organization CHRNA7 GO:0051967| negative regulation of synaptic transmission, glutamatergic GRIK2;HTR2A GO:0035094| response to nicotine CNR1;CHRNA7;CHRNA4 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0050893| sensory processing CHRNA7 GO:0035640| exploration behavior HTR1A;CHRNA4 GO:1905906| CHRNA7 GO:1905144| CHRNA7 GO:0007614| short-term memory CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;GLRA3;GRIK2;OPRM1;CHRNA7;SLC29A1;CHRNA4;GRIA2 GO:0043523| regulation of neuron apoptosis GABRA5;GPX1 GO:0007611| learning or memory CNR1;CHRNA7 GO:0001508| regulation of action potential CHRNA4;GLRA1;CACNA1G GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0007626| locomotory behavior SOD1;OPRM1;CHRNA4 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:1905920| CHRNA7 GO:0055085| transmembrane transport TRPV2;GRIK2;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;CACNA1G;ABCC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0034220| ion transmembrane transport CHRNA7;GRIA2;CHRNA4;GLRA3;GABRA1;GRIK2;GABRA6;GABRA4;GABRA2;GLRB;TRPV1;GLRA1;TRPA1;GABRA3;GABRA5 GO:0095500| CHRNA7;CHRNA4 GO:0014059| regulation of dopamine secretion CHRNA4;HTR2A GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;CHRNA4;GRIK2 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:1902991| CHRNA7 GO:0001666| response to hypoxia CAT;CHRNA7;CHRNA4;CYP1A1 GO:0140059| CHRNA7 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;GABRA3;GABRA5;TRPV2;GABRA4;GABRA6;GRIK2;GABRA1 GO:0098815| CHRNA7 GO:0007605| sensory perception of sound SOD1;GPX1;GABRA5 GO:0006979| response to oxidative stress PTGS2;SOD1;CHRNA4;GPX1;PTGS1;CAT GO:1901214| CHRNA7 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;GRIK2;CHRNA7;TRPV4;TRPM8 GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;CACNA1H;GRIK2;CHRNA4 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 18424:[DB14011 DB05194] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways GO:0006955| immune response CSF2;OPRD1;CNR2 GO:0065009| regulation of molecular function CSF2;TRPV1;CSF2RA GO:0045740| positive regulation of DNA replication CSF2;PLA2G1B GO:0008284| positive regulation of cell proliferation CSF2;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0042127| regulation of cell proliferation CSF2;PTGS2;PTGS1 GO:0030224| monocyte differentiation PPARG;CSF2 GO:0010468| regulation of gene expression CYP1A2;CSF2 GO:0045892| negative regulation of transcription, DNA-dependent CSF2;PPARG GO:0010628| positive regulation of gene expression TRPV4;CSF2 18425:[DB14011 DB07384] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07384|1-ACETYL-2-CARBOXYPIPERIDINE ATP5B common genes common pathways GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;GLRA1;TRPA1;ATP5B;CACNA1G GO:0001649| osteoblast differentiation ATP5B;CAT GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;ATP5B;CYP2C9;PPARG;PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4 GO:0001525| angiogenesis ATP5B;CYP1B1;PTGS2 18426:[DB14011 DB13994] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways GO:1902476| GLRA3;GABRA3;GLRA1;GLRB;GABRA2 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;GABRA2;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;GLRA1;CACNA1G;GABRA3 GO:0006821| chloride transport GABRA3;GLRA1;GLRB;GABRA2;GLRA3 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;GABRA2;TRPV1;GLRB;GLRA1;TRPA1;GABRA3 GO:0006810| transport TRPV1;CACNA1I;ABCG2;GABRA3;ABCC1;TRPV2 18427:[DB14011 DB07712] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07712|3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1;TRPV1;TRPV4 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;ESR1;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0048511| rhythmic process AANAT;PPARG;NCOA2 GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0007623| circadian rhythm AANAT;NCOA2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;NCOA2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TRPV1;TRPV4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG 18428:[DB14011 DB07798] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07798|(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways GO:0032259| methylation CYP1A2;PNMT 18429:[DB14011 DB02670] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SMARCA5;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;SMARCA5 18430:[DB14011 DB02755] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02755|1-3 Sugar Ring of Pentamannosyl 6-Phosphate M6PR common genes common pathways GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;M6PR;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 18431:[DB14011 DB06925] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;LCK GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;LCK;ABCG2 GO:0045087| innate immune response LCK;PPARG GO:0042127| regulation of cell proliferation PTGS1;PTGS2;LCK GO:0051209| release of sequestered calcium ion into cytosol TRPV1;LCK;TRPA1;HTR2A GO:0016032| viral reproduction VDAC1;LCK;HTR2A GO:0030217| T cell differentiation GPR18;LCK GO:0006919| activation of caspase activity PPARG;LCK 18432:[DB14011 DB08502] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08502|Capravirine CYP3A4 common genes CYP3A4 common pathways GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;PTGS1;NAAA;GPX1 18433:[DB14011 DB05685] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05685|FX06 CDH5 common genes common pathways GO:0007043| cell-cell junction assembly TRPV4;CDH5 GO:0050728| negative regulation of inflammatory response CDH5;CNR2 GO:0007155| cell adhesion CDH5;CYP1B1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CDH5;CYP1B1;PPARG 18434:[DB14011 DB01548] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes OPRM1;OPRD1 common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0042220| response to cocaine SMPD1;OPRK1;OPRM1;CNR1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0038003| opioid receptor signaling pathway OPRM1;OPRD1;OPRK1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;OPRK1;GPR18;PPARG GO:0097237| OPRD1 GO:0032100| positive regulation of appetite OPRM1 GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0032094| response to food OPRM1;CYP1A1 GO:0045087| innate immune response PPARG;TRIM13 GO:0070848| response to growth factor stimulus OPRM1 GO:0007218| neuropeptide signaling pathway GLRB;OPRK1;GLRA1;OPRM1;OPRD1;GLRA3 GO:0007626| locomotory behavior OPRK1;SOD1;OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;OPRK1 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0042060| wound healing ALOX15;OPRM1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;CYP1A2;OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4;OPRK1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0008344| adult locomotory behavior OPRD1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0007165| signal transduction TRIM13;OPRK1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0010332| response to gamma radiation GPX1;TRIM13 GO:0044849| OPRK1;OPRM1 GO:0070588| calcium ion transmembrane transport CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV1;TRPV4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0007600| sensory perception TRPV2;OPRM1;OPRK1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TRIM13;PLA2G1B;CAT GO:0010942| positive regulation of cell death PTGS2;TRIM13 GO:0006955| immune response OPRD1;CNR2;OPRK1 GO:0010629| negative regulation of gene expression OPRD1 GO:0007268| synaptic transmission VDAC1;GLRB;OPRK1;CACNA1G;GLRA1;OPRM1;OPRD1;GLRA3;HTR2A GO:0048149| behavioral response to ethanol OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2;CAT GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0000060| protein import into nucleus, translocation OPRD1 GO:0045471| response to ethanol CAT;SOD1;CNR1;OPRM1;HMGCR;OPRK1 GO:0019233| sensory perception of pain OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A;TRPV1;OPRK1;TRPA1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 18435:[DB14011 DB06996] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06996|D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide F2 common genes common pathways GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;F2 GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 18436:[DB14011 DB11256] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways GO:0006879| cellular iron ion homeostasis ABCG2;SLC46A1;SOD1 GO:0007399| nervous system development MTR;SMPD1;GLRB GO:0048678| response to axon injury MTR;SOD1 GO:0015886| heme transport ABCG2;SLC46A1 GO:0032259| methylation CYP1A2;MTR GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;TRPV3;CACNA1H;SLC46A1;TRPV2 GO:0009235| cobalamin metabolic process ABCC1;MTR 18437:[DB14011 DB08224] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08224|(1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL CES1 common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;HMGCR GO:0030855| epithelial cell differentiation CES1;VDAC1;PPARG GO:0008152| metabolic process SMPD1;CES1;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0009636| response to toxin CYP1A1;CYP1B1;CES1;CAT;GPX1 18438:[DB14011 DB11064] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV1;TRPV4 GO:0007165| signal transduction CHRNA7;AR;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;ESR1;PGR;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0007548| sex differentiation CYP17A1;AR GO:0008283| cell proliferation CYP1A1;AR;GPX1;HTR1A GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;PGR;ESR1;AR GO:0006351| transcription, DNA-dependent ESR1;AR;PPARG;PGR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression PGR;OPRD1;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0006810| transport AR;TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0010468| regulation of gene expression CYP1A2;AR GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;ESR1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;AR;ESR1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;AR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESR1;PLA2G1B;PGR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;PPARG GO:0006355| regulation of transcription, DNA-dependent PGR;PPARG;AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PGR;ESR1;AR 18439:[DB14011 DB03152] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03152|B-2-Octylglucoside polA;aqpZ;TGM3;aqpZ;petB;petA;RHO common genes common pathways GO:0007601| visual perception RHO;CRYZ;GLRA1;CYP1B1;GLRB GO:0007165| signal transduction PPARG;GPR18;RHO;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0001523| retinoid metabolic process RHO;NAPEPLD GO:0050896| response to stimulus RHO;TRPA1;TRPM8 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;RHO;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0051262| protein tetramerization CAT;HMGCR;TGM3 GO:0009416| response to light stimulus AANAT;RHO 18440:[DB14011 DB05044] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05044|PSN357 PYGL common genes common pathways GO:0008152| metabolic process PYGL;SMPD1;ACAT1 GO:0042593| glucose homeostasis CNR1;TRPV4;PYGL;PPARG GO:0043312| neutrophil degranulation PYGL;ALOX5;CAT 18441:[DB14011 DB03926] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03926|5-Alpha-Androstane-3-Beta,17-Alpha-Diol SHBG common genes common pathways 18442:[DB14011 DB07720] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes CHRNA7 common pathways GO:0045759| negative regulation of action potential CHRNB2;CNR1;CNR2 GO:0098815| CHRNA7 GO:0007605| sensory perception of sound GPX1;SOD1;CHRNB2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:0042391| regulation of membrane potential GLRB;CHRNA3;CHRNB4;GLRA1;CHRNB2;CACNA1G;CHRNA4;CACNA1H GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;CHRNA4;SOD1;PTGS2 GO:1901214| CHRNA7 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;HTR2A;GPR12 GO:1905920| CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;ALOX15 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0042220| response to cocaine CNR1;OPRM1;SMPD1;CHRNB2 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7 GO:0095500| CHRNB2;CHRNA3;CHRNA7;CHRNA4 GO:0034220| ion transmembrane transport CHRNA7;CHRNA4;CHRNA2;CHRFAM7A;GLRA3;TRPV1;GLRB;CHRNA3;TRPA1;CHRNB4;GLRA1;CHRNB2 GO:1902991| CHRNA7 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;CHRNA4 GO:0014059| regulation of dopamine secretion CHRNA4;HTR2A;CHRNB2 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CHRNB2;CYP1A1;CHRNA4;CAT;CHRNA7 GO:0007614| short-term memory CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA4;CHRNA2;SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;CHRNA3;CHRNB2;GLRA1;CHRNB4 GO:1905144| CHRNA3;CHRNB2;CHRNA7 GO:1905906| CHRNA7 GO:0001508| regulation of action potential CHRNA4;GLRA1;CHRNB4;CHRNB2;CACNA1G GO:0007612| learning PTGS2;VDAC1;CHRNB2 GO:0007611| learning or memory CHRNA7;CNR1 GO:0043312| neutrophil degranulation CAT;ALOX5;CHRNB4 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0007626| locomotory behavior OPRM1;SOD1;CHRNA4;CHRNB2;CHRNB4;CHRNA3 GO:0050808| synapse organization CHRNA7 GO:0050893| sensory processing CHRNA7 GO:0035640| exploration behavior CHRNA4;HTR1A GO:0035094| response to nicotine CHRNB2;CHRNB4;CHRNA4;CHRNA2;CHRNA7;CNR1 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A;CHRNB2 GO:0007601| visual perception GLRA1;CRYZ;CHRNB2;GLRB;CYP1B1 GO:0050890| cognition CHRNA4;CHRNA7;CHRNB2 GO:0097061| dendritic spine organization CHRNA7 GO:0007165| signal transduction SMPD1;CHRNB2;CHRNB4;GPR18;PPARG;CACNA1I;CHRNA3;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;CHRFAM7A;GPR55;HTR1A;CHRNA2;CHRNA4;CHRNA7 GO:0006939| smooth muscle contraction CHRNB4;CHRNB2;HTR2A GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;OPRM1;CACNA1H;TRPV3;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1 GO:1904645| CHRNA7 GO:1900273| CHRNA7 GO:0006811| ion transport CHRNA7;CHRNA4;TRPV2;CHRNA2;CHRFAM7A;GLRA3;CACNA1H;TRPV3;TRPM8;VDAC1;CHRNA3;TRPV4;CACNA1I;GLRB;TRPV1;CHRNB4;GLRA1;TRPA1;CACNA1G;CHRNB2 GO:0042053| regulation of dopamine metabolic process CHRNB2;HTR1A GO:0051291| protein heterooligomerization CHRNA2;GLRB;CHRNB4;GLRA1;CHRNB2 GO:0045471| response to ethanol CHRNB2;SOD1;CNR1;OPRM1;HMGCR;CAT GO:0019233| sensory perception of pain TRPV1;CHRNB2;TRPA1;CHRNA4;OPRD1;CNR2;PTGS2;OPRM1;HTR2A;CNR1 GO:0007399| nervous system development CHRNA3;GLRB;SMPD1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CHRNA2;CHRNB4;CHRNB2 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902004| CHRNA7 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;CHRNA4;GLRA3;HTR2A;OPRM1;OPRD1 GO:0008542| visual learning CHRNB2;HMGCR GO:1902430| CHRNA7 GO:0006816| calcium ion transport CHRNA7;CHRNA4;TRPV2;CACNA1H;TRPV3;TRPM8;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G;CHRNB2 18443:[DB14011 DB07694] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;TTR GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process NAPEPLD;TTR 18444:[DB14011 DB05201] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05201|V24343 CNR1 common genes CNR1 common pathways GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1;TRPA1;TRPV1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0045776| negative regulation of blood pressure CNR1 GO:0045471| response to ethanol CAT;CNR1;SOD1;OPRM1;HMGCR GO:0060259| regulation of feeding behavior CNR1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0010976| positive regulation of neuron projection development CNR1 GO:0099553| CNR1 GO:0050796| regulation of insulin secretion CNR1 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG GO:0031999| negative regulation of fatty acid beta-oxidation CNR1 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0045777| positive regulation of blood pressure CNR1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0038171| CNR1;GPR55;CNR2 GO:0051966| regulation of synaptic transmission, glutamatergic CNR1 GO:0007611| learning or memory CNR1;CHRNA7 GO:0060135| maternal process involved in female pregnancy CNR1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0060405| regulation of penile erection CNR1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1 GO:0043271| negative regulation of ion transport CNR1 GO:0033602| negative regulation of dopamine secretion CNR1 GO:0007413| axonal fasciculation CNR1 GO:0035094| response to nicotine CHRNA7;CNR1 GO:0043278| response to morphine CNR1;OPRM1 GO:0033004| negative regulation of mast cell activation CNR2;CNR1 GO:0007568| aging CYP1A1;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT GO:0045759| negative regulation of action potential CNR1;CNR2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0042220| response to cocaine SMPD1;OPRM1;CNR1 GO:0051001| negative regulation of nitric-oxide synthase activity CNR2;CNR1 GO:0002866| positive regulation of acute inflammatory response to antigenic stimulus CNR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1 GO:0007283| spermatogenesis CNR1;SOD1 18445:[DB14011 DB05451] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05451|P54 NFKB2;NFKB1 common genes common pathways GO:0032496| response to lipopolysaccharide IDO1;NFKB2;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;PPARG;NFKB2;PLA2G1B GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;NFKB1;CAT;GPX1 GO:0045087| innate immune response NFKB2;PPARG;NFKB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;NFKB2;PPARG;NFKB1 GO:0034097| response to cytokine stimulus AANAT;PTGS2;NFKB2 GO:0043312| neutrophil degranulation ALOX5;CAT;NFKB1 GO:0006355| regulation of transcription, DNA-dependent NFKB1;PPARG;NFKB2 GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;PPARG GO:0050728| negative regulation of inflammatory response CNR2;NFKB1 GO:0007568| aging HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT;NFKB2;CYP1A1 GO:0006915| apoptotic process GPX1;NFKB1;VDAC1 GO:0048511| rhythmic process NFKB2;PPARG;AANAT GO:0071356| cellular response to tumor necrosis factor TRPV1;NFKB1 GO:0045892| negative regulation of transcription, DNA-dependent NFKB1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;PPARG GO:0006351| transcription, DNA-dependent NFKB2;PPARG;NFKB1 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0010629| negative regulation of gene expression OPRD1;NFKB1 GO:0006954| inflammatory response NFKB2;IDO1;ALOX15;TRPV1;PTGS2;CNR2;NFKB1;ALOX5;PTGS1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;NFKB2;NFKB1;CAT GO:0007165| signal transduction GPR18;NFKB2;PPARG;SMPD1;PLA2G1B;CACNA1I;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;NFKB1 18446:[DB14011 DB03566] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;TRPA1;CACNA1G;SLC22A1;ABCC1;TRPV2;CACNA1H;TRPV3;SLC22A4 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;SLC22A4;GLRA3;CHRNA7 GO:0098869| GSR;CAT;PTGS1;GPX1;TXNRD1;PTGS2 GO:0051260| protein homooligomerization SLC22A1;GLRA1;GLRA3;ACAT1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;ADRB1;ADRB2;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0055114| oxidation-reduction process CAT;TXNRD1;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0022900| electron transport chain CYP1A2;TXNRD1;GSR;IDO1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ADRB2 GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1;ADRB2 GO:0034599| cellular response to oxidative stress CAT;TXNRD1;GPX1;SOD1;GSR GO:0006812| cation transport TRPM8;SLC22A1 GO:0006855| drug transmembrane transport ABCC1;SLC22A1;ABCG2 GO:0015949| nucleobase-containing small molecule interconversion TXNRD1;GSR GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;SLC22A4;GLRA3;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;CACNA1G;SLC22A1;TRPA1;GLRA1 GO:0008283| cell proliferation HTR1A;GPX1;TXNRD1;CYP1A1 GO:0006641| triglyceride metabolic process SLC22A4;CAT;GPX1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;ADRB1;CACNA1I;HTR1A;GPR55;HTR2A;CNR1;GPR12;ADRB2;OPRM1;CNR2;OPRD1;CHRNA7;TXNRD1 GO:0045453| bone resorption GPR55;ADRB2 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;CNR1;HMGCR;TXNRD1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0045454| cell redox homeostasis GPX1;TXNRD1;GSR GO:0009409| response to cold ADRB2;TRPA1;PPARG;TRPM8;ADRB1 GO:0001659| temperature homeostasis GPX1;HTR2A;ADRB1;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPA1;TRPV1 GO:0050873| brown fat cell differentiation PTGS2;ADRB2;ADRB1 18447:[DB14011 DB09331] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09331|Daratumumab CD38 common genes common pathways GO:0032526| response to retinoic acid CD38;PPARG GO:0034097| response to cytokine stimulus AANAT;PTGS2;CD38 GO:0043066| negative regulation of apoptotic process SOD1;CD38;HMGCR;PTGS2;CAT;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent CD38;PPARG GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CD38;CAT GO:0033194| response to hydroperoxide GPX1;CD38 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;CD38 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CD38 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;CD38 GO:0007565| female pregnancy CD38;IDO1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;CD38;TRPV4;TRPV1 GO:0007165| signal transduction CHRNA7;CD38;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0009725| response to hormone stimulus CD38;ACAT1 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;CD38 18448:[DB14011 DB06111] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06111|AB192 MPO common genes common pathways GO:0042744| hydrogen peroxide catabolic process CAT;MPO;GPX1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;MPO;PTGS1;GPX1 GO:0007568| aging CYP1A1;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;MPO;CAT GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;GPX1;MPO;ALOX5;PTGS1 GO:0032094| response to food OPRM1;MPO;CYP1A1 GO:0043312| neutrophil degranulation MPO;ALOX5;CAT GO:0009612| response to mechanical stimulus MPO;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;MPO;GPX1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;MPO;CYP1A1;IDO1 GO:0019430| removal of superoxide radicals MPO;SOD1 18449:[DB14011 DB01992] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01992|Coenzyme A acs;DBI;CRAT;glcB;coaD;acpS;HMGCR;KAT5;dapD;ACAT2;vatD;CS;fabH;coaA;fabH;KAT2A;KAT2B;cysE;gltA;glmU common genes HMGCR common pathways GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;KAT2B GO:0010664| negative regulation of striated muscle cell apoptosis HMGCR GO:0048643| positive regulation of skeletal muscle tissue development HMGCR GO:0008283| cell proliferation HTR1A;KAT2A;GPX1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;KAT2A;PPARG;CYP1A1;TRPA1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;KAT2B GO:0006743| ubiquinone metabolic process HMGCR GO:0015936| coenzyme A metabolic process HMGCR;ACAT1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG GO:0008542| visual learning HMGCR GO:0016032| viral reproduction KAT2A;KAT5;HTR2A;KAT2B;VDAC1 GO:0045445| myoblast differentiation HMGCR GO:0031667| response to nutrient levels SOD1;KAT2A GO:1990090| TRPV1;KAT2A GO:0007399| nervous system development KAT2A;SMPD1;GLRB GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;ACAT2;NAPEPLD;CRAT;CYP3A4 GO:0016126| sterol biosynthetic process HMGCR GO:0008152| metabolic process SMPD1;ACAT1;ACAT2 GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT GO:0006351| transcription, DNA-dependent PPARG;KAT2B;KAT5;KAT2A GO:0006357| regulation of transcription from RNA polymerase II promoter KAT2A;PPARG GO:0061045| negative regulation of wound healing HMGCR GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1 GO:0048511| rhythmic process PPARG;KAT2B;AANAT GO:0071356| cellular response to tumor necrosis factor TRPV1;KAT2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;KAT5 GO:0051262| protein tetramerization HMGCR;CAT GO:0045540| regulation of cholesterol biosynthetic process HMGCR GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;CHRNA7 GO:0008299| isoprenoid biosynthetic process HMGCR GO:0097756| HMGCR;PTGS2 GO:1903146| KAT2A;VDAC1 GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CYP1A1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;KAT2B GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0006694| steroid biosynthetic process HMGCR;CYP17A1 GO:0055114| oxidation-reduction process GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0006355| regulation of transcription, DNA-dependent KAT2B;KAT5;KAT2A;PPARG GO:0010666| positive regulation of cardiac muscle cell apoptosis HMGCR GO:0045893| positive regulation of transcription, DNA-dependent KAT5;KAT2B;PPARG GO:0006631| fatty acid metabolic process PTGS1;PTGS2;CRAT;ALOX15 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;KAT5 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter KAT5;KAT2B;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR GO:0006635| fatty acid beta-oxidation ACAT1;ACAT2 GO:0006695| cholesterol biosynthetic process ACAT2;HMGCR GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR GO:0008203| cholesterol metabolic process CAT;HMGCR GO:0036151| PLA2G1B;DBI 18450:[DB14011 DB00008] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00008|Peginterferon alfa-2a IFNAR2;IFNAR1;CYP1A2 common genes CYP1A2 common pathways GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP1A1;CYP2C9;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0032259| methylation CYP1A2 GO:0009615| response to virus IFNAR2;IFNAR1;CYP1A1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;IFNAR1;CYP1A2;IDO1;CYP1A1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0045333| cellular respiration CYP1A2 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNAR2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 18451:[DB14011 DB04432] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04432|ZK-805623 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18452:[DB14011 DB04783] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04783|Sphinxolide B ACTA1 common genes common pathways GO:0009612| response to mechanical stimulus ACTA1;TRPV4;PPARG GO:0006936| muscle contraction CACNA1H;ACTA1;GLRA1 GO:0010628| positive regulation of gene expression ACTA1;TRPV4 GO:0048741| skeletal muscle fiber development GPX1;ACTA1 GO:0010226| response to lithium ion PTGS2;ACTA1 18453:[DB14011 DB01977] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01977|6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0043312| neutrophil degranulation CAT;ALOX5;PLAU GO:0001666| response to hypoxia CYP1A1;PLAU;CHRNA7;CAT GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;PLAU 18454:[DB14011 DB04915] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04915|Idronoxil ENOX2 common genes common pathways GO:0048511| rhythmic process PPARG;ENOX2;AANAT GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1A1;CYP2C9;CRYZ;ALOX5;PTGS1;GPX1;CAT;ENOX2;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 18455:[DB14011 DB04997] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04997|ATL1102 ITGA4 common genes common pathways GO:0071345| cellular response to cytokine stimulus ITGA4;TRPV1 GO:0007155| cell adhesion CYP1B1;ITGA4 18456:[DB14011 DB05091] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05091|M0002 AVPR2 common genes common pathways GO:0034097| response to cytokine stimulus AVPR2;PTGS2;AANAT GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;AVPR2 GO:0010628| positive regulation of gene expression AVPR2;TRPV4 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;AVPR2;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;AVPR2 GO:0045777| positive regulation of blood pressure AVPR2;CNR1 GO:0007165| signal transduction PLA2G1B;CACNA1I;AVPR2;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0032870| cellular response to hormone stimulus AVPR2;CACNA1H GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;AVPR2 18457:[DB14011 DB00704] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00704|Naltrexone OPRD1;OPRM1;OPRK1;SIGMAR1;UGT1A1 common genes OPRD1;OPRM1 common pathways GO:0007399| nervous system development GLRB;SMPD1;SIGMAR1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0009314| response to radiation PTGS2;OPRM1;CAT;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0008152| metabolic process ACAT1;SMPD1;UGT1A1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0000060| protein import into nucleus, translocation OPRD1 GO:0001889| liver development CYP1A1;UGT1A1;ACAT1 GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPV1;OPRK1;TRPA1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1;CYP1A1;CYP2D6;CYP2C19 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0007600| sensory perception OPRM1;TRPV2;OPRK1 GO:0006955| immune response OPRK1;CNR2;OPRD1 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;GLRA3;VDAC1;GLRB;OPRK1;CACNA1G;GLRA1 GO:0010629| negative regulation of gene expression OPRD1 GO:0048149| behavioral response to ethanol OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRK1;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7 GO:0007610| behavior HTR2A;HTR1A;OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus TRPM8;OPRK1 GO:0070588| calcium ion transmembrane transport CACNA1H;OPRM1;TRPV3;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV4;CACNA1I;TRPV1;TRPM8 GO:0044849| OPRK1;OPRM1 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV1;TRPV4 GO:0071315| cellular response to morphine OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007584| response to nutrient HMGCR;CNR1;UGT1A1;PPARG GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0032868| response to insulin stimulus TRPV4;OPRK1;CAT;AANAT GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0042755| eating behavior OPRM1;OPRD1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG;UGT1A1 GO:0042594| response to starvation ACAT1;UGT1A1;PPARG GO:0007626| locomotory behavior OPRK1;SOD1;OPRM1 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;GLRB;OPRK1;GLRA1 GO:0070848| response to growth factor stimulus OPRM1 GO:0070207| protein homotrimerization SIGMAR1;TRPM8 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;HTR2A GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;UGT1A1;CYP1A1 GO:0042060| wound healing ALOX15;OPRM1 GO:0043523| regulation of neuron apoptosis GPX1;SIGMAR1 GO:0032100| positive regulation of appetite OPRM1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0097237| OPRD1 GO:0043278| response to morphine OPRK1;OPRM1;CNR1 GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;UGT1A1;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0032094| response to food CYP1A1;OPRM1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9;UGT1A1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0038003| opioid receptor signaling pathway OPRD1;SIGMAR1;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;OPRK1;PPARG;GPR18 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;UGT1A1;CYP1A1;CYP2C9;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1;UGT1A1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0042220| response to cocaine OPRK1;SMPD1;CNR1;OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 18458:[DB14011 DB00018] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00018|Interferon alfa-n3 IFNAR1;IFNAR2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;OPRM1;CYP1A2;IFNAR1;CNR2;PTGS2;CNR1 GO:0009615| response to virus CYP1A1;IFNAR1;IFNAR2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNAR2 18459:[DB14011 DB04107] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04107|[(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18460:[DB14011 DB07334] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07334|N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation KDR;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;KDR;ALOX15 GO:0001525| angiogenesis KDR;CYP1B1;PTGS2 GO:0016032| viral reproduction HTR2A;VDAC1;KDR GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 18461:[DB14011 DB08172] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0031000| response to caffeine DHODH;PPARG GO:0055114| oxidation-reduction process CAT;DHODH;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0042493| response to drug ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;CAT;DHODH;CYP1A2;PTGS2;HTR2A;SOD1 GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0014070| response to organic cyclic compound DHODH;AANAT;ACAT1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy DHODH;IDO1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;DHODH 18462:[DB14011 DB00790] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC15A2;TRPV2;CACNA1G;ABCC1;SLC15A1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8 GO:0010628| positive regulation of gene expression TRPV4;SFRP4 GO:0007283| spermatogenesis ACE;CNR1;SOD1 GO:0002446| neutrophil mediated immunity PLA2G1B;ACE GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;CNR2;OPRM1;SFRP4;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0006810| transport TRPV2;SLC15A2;ABCG2;CACNA1I;TRPV1;SLC15A1;ABCC1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;BCHE;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0001822| kidney development ACE;CAT GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLC15A2;CACNA1H;TRPV3;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPA1;GLRA1;SLC15A1;CACNA1G GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BCHE;SFRP4;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PTGS1;ACE;PTGS2;SOD1;PPARG GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0060047| heart contraction SOD1;GPX1;ACE GO:0009725| response to hormone stimulus ACAT1;SFRP4 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;SFRP4;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 18463:[DB14011 DB01962] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC;KIT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0007283| spermatogenesis CNR1;SOD1;KIT GO:0010628| positive regulation of gene expression KIT;SRC;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;SRC;ALOX15;TRPV4 GO:0031532| actin cytoskeleton reorganization KIT;TRPV4 GO:0001541| ovarian follicle development SOD1;KIT GO:0000187| activation of MAPK activity SOD1;CHRNA7;KIT;PLA2G1B GO:0046686| response to cadmium ion CAT;KIT GO:0002376| immune system process IDO1;SRC;HCK GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KIT;CAT GO:0006687| glycosphingolipid metabolic process SMPD1;KIT GO:0060326| cell chemotaxis KIT;ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC;KIT GO:0046427| positive regulation of JAK-STAT cascade KIT;CYP1B1 GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;SRC;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0007155| cell adhesion CYP1B1;SRC;HCK GO:0045087| innate immune response PPARG;HCK;SRC GO:0008284| positive regulation of cell proliferation CHRNA7;KIT;HCK;HTR1A;HTR2A;PTGS2;HMGCR GO:0009615| response to virus SRC;CYP1A1 GO:0043066| negative regulation of apoptotic process CAT;SRC;GPX1;HCK;SOD1;PTGS2;HMGCR GO:0009612| response to mechanical stimulus TRPV4;PPARG;SRC GO:0042127| regulation of cell proliferation KIT;SRC;PTGS1;PTGS2 GO:0030838| positive regulation of actin filament polymerization ALOX15;HCK GO:0008283| cell proliferation HTR1A;GPX1;SRC;CYP1A1 GO:0007165| signal transduction HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;KIT;SRC;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption SRC;GPR55 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0048565| digestive tract development KIT;CYP1A1 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0008542| visual learning KIT;HMGCR GO:0030217| T cell differentiation GPR18;KIT GO:0006954| inflammatory response PTGS2;CNR2;HCK;KIT;PTGS1;ALOX5;IDO1;ALOX15;TRPV1 GO:0016032| viral reproduction VDAC1;HCK;SRC;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0031667| response to nutrient levels SRC;SOD1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0009314| response to radiation OPRM1;PTGS2;KIT;CAT GO:0042542| response to hydrogen peroxide TRPA1;SRC;GPX1;CAT;SOD1 GO:0043065| positive regulation of apoptotic process SRC;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0050727| regulation of inflammatory response HCK;PTGS2 GO:0035556| intracellular signal transduction SRC;KIT;PLA2G1B GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;KIT 18464:[DB14011 DB01835] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;NOS2;CYP1A1;IDO1 GO:0055114| oxidation-reduction process CRYZ;NOS2;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0010629| negative regulation of gene expression NOS2;OPRD1 18465:[DB14011 DB03419] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;UCKL1 GO:0016032| viral reproduction HTR2A;VDAC1;UCKL1 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;DPYD;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR 18466:[DB14011 DB01296] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes CYP2C19 common pathways GO:0050796| regulation of insulin secretion TNF;CNR1;IFNG GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0007566| embryo implantation MMP9;PTGS2;SOD1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;TNF GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;NFKB2;PPARG;PLA2G1B;CACNA1I GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IFNG GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0006919| activation of caspase activity PPARG;TNF GO:0071276| cellular response to cadmium ion MMP9;CYP1A2;SOD1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNG GO:0045471| response to ethanol CAT;CNR1;SOD1;CYP2E1;HMGCR;OPRM1 GO:0000060| protein import into nucleus, translocation TNF;IFNG;OPRD1 GO:0031622| positive regulation of fever generation TNF;PTGS2;CNR1 GO:0006351| transcription, DNA-dependent NFKB2;PPARG GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0001503| ossification MMP9;ALOX15 GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TNF;MMP9;TRPV1;CYP1B1;IDO1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0001934| positive regulation of protein phosphorylation TNF;MMP9;CHRNA7;IFNG GO:0010629| negative regulation of gene expression OPRD1;IFNG;TNF GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNF;NFKB2;PLA2G1B GO:0006954| inflammatory response NFKB2;TNF;ALOX15;IDO1;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0006955| immune response TNF;OPRD1;CNR2;IFNG GO:0007568| aging CYP1A1;NFKB2;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CAT GO:0032735| positive regulation of interleukin-12 production IDO1;IFNG GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0043388| positive regulation of DNA binding MMP9;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TRPV1;PTGS2;OPRM1;IFNG GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4;TNF GO:0006915| apoptotic process VDAC1;IFNG;GPX1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;TNF GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0048511| rhythmic process AANAT;PPARG;NFKB2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;TNF;PTGS2;CYP1A2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG;IFNG GO:0010628| positive regulation of gene expression TNF;TRPV4;IFNG GO:0010193| response to ozone CYP2E1;CAT GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0042127| regulation of cell proliferation TNF;PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;NFKB2;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0045087| innate immune response NFKB2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TNF;NFKB2;TRPV1;TRPV4;IFNG GO:0034097| response to cytokine stimulus NFKB2;AANAT;PTGS2 GO:0043312| neutrophil degranulation MMP9;ALOX5;CAT GO:0009615| response to virus IFNG;TNF;CYP1A1 GO:0008284| positive regulation of cell proliferation CHRNA7;IFNG;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB2;TNF;PPARG;PLA2G1B GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;IFNG GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;MMP9 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;CYP2E1;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;GPX1;ALOX5;PTGS1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP2E1;CYP1A2;PTGS2 GO:0006355| regulation of transcription, DNA-dependent NFKB2;PPARG GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;HMGCR;PTGS2 18467:[DB14011 DB12866] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;SLC22A8;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0098656| SLC22A8;VDAC1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLC22A8;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 18468:[DB14011 DB02974] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2B6;CYP1A1;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP2B6;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2B6;CYP2C19;CYP1B1;CYP1A2 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP2B6;CRYZ GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2B6;CYP2C19 18469:[DB14011 DB01412] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes CYP1A2 common pathways GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 GO:0050728| negative regulation of inflammatory response ADORA1;ADORA2A;CNR2 GO:0051967| negative regulation of synaptic transmission, glutamatergic ADORA1;HTR2A GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0042493| response to drug ADORA2A;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;CYP2E1;PTGS2;CYP1A2;CAT GO:0006355| regulation of transcription, DNA-dependent ADORA2A;PPARG GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4B GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA1 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;CYP2E1;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0042311| vasodilation GPX1;ADORA2A GO:0032259| methylation CYP1A2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ADORA1 GO:0007626| locomotory behavior ADORA2A;OPRM1;SOD1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0035307| positive regulation of protein dephosphorylation ADORA1;SMPD1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;ADORA1;ADORA2A;GLRA1;TRPV1;GLRB GO:0001666| response to hypoxia CHRNA7;CAT;ADORA1;CYP1A1 GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0010193| response to ozone CYP2E1;CAT GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0031000| response to caffeine PPARG;ADORA2A GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0016042| lipid catabolic process DAGLA;PLA2G1B;ADORA1;NAPEPLD GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0006915| apoptotic process ADORA2A;VDAC1;GPX1 GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;ADORA2A;PPARG;ADORA1;PDE4B GO:0097756| ADORA1;PTGS2;HMGCR GO:0010468| regulation of gene expression CYP1A2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ADORA1;ADORA2A;PTGS1;ALOX5;PTGS2;CNR2 GO:0007600| sensory perception ADORA2A;OPRM1;TRPV2 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;ADORA1;HTR2A GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;GPX1;PTGS2 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0001659| temperature homeostasis TRPV1;ADORA1;GPX1;HTR2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADORA2A GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9;NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0007399| nervous system development GLRB;ADORA1;SMPD1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0045471| response to ethanol CNR1;SOD1;CYP2E1;HMGCR;OPRM1;CAT GO:0045776| negative regulation of blood pressure CNR1;ADORA1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0008285| negative regulation of cell proliferation PPARG;ADORA1;ADORA2A;CYP1B1;OPRM1;PTGS2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADORA1 GO:0042755| eating behavior ADORA2A;OPRD1;OPRM1 GO:0032229| negative regulation of synaptic transmission, GABAergic CNR2;ADORA1 GO:0045777| positive regulation of blood pressure CNR1;ADORA1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;SOD1;OPRD1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0007165| signal transduction CACNA1I;PLA2G1B;PDE4B;SMPD1;ADORA1;PPARG;ADORA2A;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0001975| response to amphetamine SOD1;CNR2;ADORA2A GO:0050890| cognition ADORA1;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADORA1 18470:[DB14011 DB04674] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0014824| artery smooth muscle contraction EDNRA;HTR2A GO:0055114| oxidation-reduction process CYP3A4;SOD1;AKR1C1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1 GO:0042574| retinal metabolic process CYP1B1;AKR1C1 GO:0051260| protein homooligomerization GLRA1;GLRA3;AKR1C1;ACAT1 GO:0007186| G-protein coupled receptor signaling pathway EDNRA;PPARG;GPR18;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0006810| transport TTR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0007202| activation of phospholipase C activity EDNRA;HTR2A;GPR55 GO:0001666| response to hypoxia CYP1A1;EDNRA;CAT;CHRNA7 GO:0015758| glucose transport PLA2G1B;EDNRA GO:0030855| epithelial cell differentiation VDAC1;PPARG;AKR1C1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;AKR1C1;CYP3A4 GO:0042310| vasoconstriction EDNRA;HTR1A GO:0042572| retinol metabolic process CYP1B1;TTR GO:0007507| heart development PPARG;EDNRA GO:0042448| progesterone metabolic process AKR1C1;CYP17A1 GO:0006939| smooth muscle contraction HTR2A;EDNRA GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;EDNRA;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;EDNRA GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;EDNRA;TRPV1;TRPV4 GO:0001523| retinoid metabolic process NAPEPLD;AKR1C1;TTR GO:0008217| regulation of blood pressure EDNRA;PPARG;PTGS1;SOD1;PTGS2 GO:0008283| cell proliferation CYP1A1;EDNRA;HTR1A;GPX1 18471:[DB14011 DB13150] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F3;GPX1;F10 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;F3 GO:0006919| activation of caspase activity F3;PPARG 18472:[DB14011 DB00521] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes CYP2D6 common pathways GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0045453| bone resorption ADRB2;GPR55 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;ADRB2;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;ADRB1;CACNA1I;PLA2G1B GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0009409| response to cold ADRB2;PPARG;TRPA1;TRPM8;ADRB1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0001659| temperature homeostasis TRPV1;ADRB1;HTR2A;GPX1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0051100| negative regulation of binding CYP2D6 GO:0050873| brown fat cell differentiation ADRB1;ADRB2;PTGS2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPA1;TRPV1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;ADRB1;OPRD1;CNR2;OPRM1;ADRB2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;FAAH GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A1;CYP2C9;CRYZ GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;PLA2G1B GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1;ADRB2 18473:[DB14011 DB06842] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;PDE4A;OPRD1;PDE4D;CHRNA7 GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;PDE4A;PDE4D;OPRM1;CNR2;GPR18;PPARG GO:0007568| aging CYP1A1;PTGS2;PDE4D;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B 18474:[DB14011 DB05419] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05419|ADX-10061 CALY common genes common pathways 18475:[DB14011 DB07695] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways GO:0006810| transport ABCC1;ABCG2;CACNA1I;TRPV1;TTR;TRPV2 GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process TTR;CYP1B1 18476:[DB14011 DB07851] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 18477:[DB14011 DB06782] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06782|Dimercaprol APP common genes common pathways GO:0001774| microglial cell activation APP;TRPV1 GO:0007399| nervous system development APP;SMPD1;GLRB GO:1990090| TRPV1;APP GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;APP;SMPD1;CNR1;SOD1;PTGS2 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0001934| positive regulation of protein phosphorylation APP;CHRNA7 GO:1902004| CHRNA7;APP GO:0071320| cellular response to cAMP APP;AANAT GO:0010629| negative regulation of gene expression APP;OPRD1 GO:0007268| synaptic transmission OPRD1;OPRM1;GLRA3;HTR2A;APP;CACNA1G;GLRA1;GLRB;VDAC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0008542| visual learning HMGCR;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;APP;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;PPARG GO:0007204| elevation of cytosolic calcium ion concentration APP;TRPV4;TRPV1;OPRM1;HTR2A GO:0007613| memory APP;CHRNA7;CNR1;HTR2A;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;APP GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP GO:1900273| APP;CHRNA7 GO:0008344| adult locomotory behavior APP;OPRD1 GO:0061844| APP;PLA2G1B GO:0032930| positive regulation of superoxide anion generation SOD1;APP GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;APP;OPRM1;PTGS2 GO:1905906| APP;CHRNA7 GO:0046330| positive regulation of JNK cascade APP;TRPV4 GO:0007612| learning PTGS2;APP;VDAC1 GO:0008203| cholesterol metabolic process APP;HMGCR;CAT GO:0007611| learning or memory APP;CHRNA7;CNR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;APP;TRPV4;TRPV1 GO:0045087| innate immune response APP;PPARG GO:0007155| cell adhesion CYP1B1;APP GO:0010288| response to lead ion CAT;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;APP GO:0007626| locomotory behavior OPRM1;SOD1;APP GO:0002576| platelet degranulation APP;SOD1 GO:0019731| antibacterial humoral response APP;PLA2G1B GO:0050808| synapse organization CHRNA7;APP GO:0050830| defense response to Gram-positive bacterium APP;PLA2G1B GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0010468| regulation of gene expression CYP1A2;APP GO:0007186| G-protein coupled receptor signaling pathway APP;GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0098815| APP;CHRNA7 GO:0051260| protein homooligomerization ACAT1;GLRA3;APP;GLRA1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;APP GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;APP;OPRM1;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HMGCR;OPRM1;HTR2A;GPR55;TRPV4;ALOX15;APP GO:0006915| apoptotic process APP;VDAC1;GPX1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;APP;PLA2G1B GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0051262| protein tetramerization HMGCR;CAT;APP GO:0010628| positive regulation of gene expression APP;TRPV4 18478:[DB14011 DB03083] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03083|IC261 CSNK1G2 common genes common pathways GO:0007165| signal transduction CSNK1G2;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B 18479:[DB14011 DB07765] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07765|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP2C9;CYP1A1;CRYZ;PTGS1;ALOX5;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;DHRS4L1;HMGCR;CYP3A4;SOD1 18480:[DB14011 DB02773] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes PTGS1 common pathways GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;GPX1;PTGS1;CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;CNR2;PTGS2 18481:[DB14011 DB06769] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06769|Bendamustine CYP1A2 common genes CYP1A2 common pathways GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0032259| methylation CYP1A2 GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0010468| regulation of gene expression CYP1A2 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;NAAA;GPX1;PTGS1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0045333| cellular respiration CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 18482:[DB14011 DB05022] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways GO:0048511| rhythmic process PPARG;TOP2A;AANAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;TOP2A;SMPD1;CNR1;SOD1;PTGS2 18483:[DB14011 DB06972] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06972|7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile ITGAL common genes common pathways GO:0007155| cell adhesion CYP1B1;ITGAL GO:0043312| neutrophil degranulation ALOX5;CAT;ITGAL GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;ITGAL;OPRM1;CNR2;OPRD1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;ITGAL;TRPV1;IDO1;ALOX15 18484:[DB14011 DB00192] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00192|Indecainide SCN5A common genes common pathways GO:0086002| SCN5A;CACNA1G GO:0055085| transmembrane transport TRPV2;SCN5A;CACNA1H;TRPV3;TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0086015| CACNA1G;SCN5A GO:0086016| CACNA1G;SCN5A GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0086046| SCN5A;CACNA1G GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN5A GO:0006811| ion transport TRPV2;SCN5A;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0086045| CACNA1G;SCN5A GO:0002027| regulation of heart rate CACNA1G;SCN5A GO:0019228| regulation of action potential in neuron CACNA1G;CACNA1I;CACNA1H;SCN5A GO:0035725| sodium ion transmembrane transport SCN5A;CACNA1H;CACNA1I;CACNA1G GO:0071277| cellular response to calcium ion SCN5A;ALOX15 GO:0086091| SCN5A;CACNA1G GO:0086010| CACNA1H;SCN5A;CACNA1G;CACNA1I 18485:[DB14011 DB00534] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;ALDH5A1;CYP1B1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;SLC12A1;GLRA1;TRPA1;GLRB;TRPV1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;SLC12A1;ABCC1;CACNA1G;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;SLC12A1;TRPV2 GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPM8;ALDH5A1;TRPV1;CAT GO:1902476| SLC12A1;GLRA3;GLRB;GLRA1 GO:0008152| metabolic process SMPD1;ALDH5A1;ACAT1 GO:0006749| glutathione metabolic process ALDH5A1;GSR;GPX1;SOD1 GO:0009791| post-embryonic development CYP1A2;ALDH5A1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;GLRA3;TRPV3;CACNA1H;CHRNA7;SLC12A1;TRPV2 18486:[DB14011 DB02215] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02215|Furoyl-Leucine ADAM28 common genes common pathways GO:0007283| spermatogenesis ADAM28;SOD1;CNR1 18487:[DB14011 DB08299] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;PDE4A;OPRD1;PDE4D;HTR1A;GPR55;HTR2A;GPR12;CNR1;PLA2G1B;CACNA1I;PDE4B;SMPD1;PPARG;GPR18 GO:0002027| regulation of heart rate CACNA1G;PDE4D GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;PDE4A;OPRD1;PDE4D;PDE4B;PPARG;GPR18 GO:0007568| aging PTGS2;PDE4D;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT;CYP1A1 GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B;PDE4D 18488:[DB14011 DB00229] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2;ABCC1;SLC22A6;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H;SLC22A8 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0006811| ion transport TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;CACNA1H;TRPV3;SLC22A8;GLRA3 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;GPX1;CAT GO:0098656| SLC22A8;SLC22A6;VDAC1 18489:[DB14011 DB05210] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0010628| positive regulation of gene expression MTOR;TRPV4 GO:0048714| positive regulation of oligodendrocyte differentiation MTOR;PPARG GO:0048511| rhythmic process PPARG;AANAT;PRKDC GO:0043200| response to amino acid stimulus GLRB;MTOR;GLRA3 GO:0045671| negative regulation of osteoclast differentiation GPR55;PIK3R1 GO:0050769| positive regulation of neurogenesis MTOR;OPRM1 GO:0042220| response to cocaine MTOR;SMPD1;OPRM1;CNR1 GO:0002376| immune system process PRKDC;IDO1 GO:0048538| thymus development PRKDC;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;MTOR;PTGS2;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway PIK3R1;PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;MTOR GO:0048661| positive regulation of smooth muscle cell proliferation MTOR;HMGCR;PTGS2 GO:0043278| response to morphine MTOR;OPRM1;CNR1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PIK3R1;MTOR;PIK3R2 GO:0007569| cell aging SOD1;MTOR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PIK3R1;PIK3R2;PPARG;PRKDC GO:0043066| negative regulation of apoptotic process PIK3R1;SOD1;HMGCR;PTGS2;PRKDC;CAT;GPX1 GO:0045087| innate immune response PRKDC;PPARG GO:0042060| wound healing OPRM1;MTOR;ALOX15 GO:0060135| maternal process involved in female pregnancy MTOR;CNR1 GO:0030838| positive regulation of actin filament polymerization MTOR;ALOX15 GO:0071230| cellular response to amino acid stimulus MTOR;GLRA1 GO:0009791| post-embryonic development MTOR;CYP1A2 GO:0034976| response to endoplasmic reticulum stress ALOX15;PIK3R1;PIK3R2 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;PRKDC GO:0007584| response to nutrient PPARG;MTOR;CNR1;HMGCR GO:0014823| response to activity PRKDC;CAT GO:0008283| cell proliferation CYP1A1;GPX1;PRKDC;HTR1A GO:0032868| response to insulin stimulus TRPV4;MTOR;AANAT;CAT GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;PIK3R1;PIK3R2 GO:0007420| brain development MTOR;ACAT1;PRKDC GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PIK3R1;PLA2G1B;CACNA1I;PPARG;GPR18;PIK3R2;SMPD1;MTOR GO:0034644| cellular response to UV PIK3R1;PTGS2 GO:0010332| response to gamma radiation PRKDC;GPX1 GO:0032869| cellular response to insulin stimulus PPARG;PIK3R2;PIK3R1;PLA2G1B;PRKDC GO:0010976| positive regulation of neuron projection development CNR1;MTOR GO:0010942| positive regulation of cell death MTOR;PTGS2 GO:0016032| viral reproduction VDAC1;PIK3R1;HTR2A GO:0043087| regulation of GTPase activity SOD1;MTOR GO:0042752| regulation of circadian rhythm PRKDC;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;HTR2A GO:0008542| visual learning HMGCR;MTOR GO:0045859| regulation of protein kinase activity SOD1;MTOR GO:0001934| positive regulation of protein phosphorylation CHRNA7;MTOR GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;PRKDC;CNR1;SOD1 GO:0007507| heart development PRKDC;PPARG 18490:[DB14011 DB00963] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes PTGS1;PTGS2 common pathways GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT;CYP1A1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0009750| response to fructose stimulus PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;ACAT1;AANAT GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;CNR2;PTGS2;PTGS1;ALOX5 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;TRPV1;TRPA1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:1990776| PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG;NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4 18491:[DB14011 DB07872] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07872|5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 18492:[DB14011 DB00574] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00574|Fenfluramine SLC6A4;HTR2B;HTR2C;HTR2A;CYP2D6 common genes CYP2D6;HTR2A common pathways GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7;SLC6A4 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;OPRM1 GO:0046718| entry of virus into host cell HTR2A GO:0007420| brain development ACAT1;SLC6A4 GO:0007165| signal transduction PLA2G1B;CACNA1I;HTR2B;HTR2C;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0007610| behavior HTR1A;HTR2A;HTR2C;HTR2B GO:0001819| positive regulation of cytokine production SOD1;HTR2B GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;HTR2B GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0006939| smooth muscle contraction HTR2A;HTR2B GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;SLC6A4;CAT GO:0043267| negative regulation of potassium ion transport HTR2A GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0001662| behavioral fear response VDAC1;HTR2C;HTR1A GO:0007584| response to nutrient SLC6A4;HMGCR;CNR1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;HTR2C;PPARG GO:0051781| positive regulation of cell division CAT;HTR2B GO:0051100| negative regulation of binding CYP2D6 GO:0030431| sleep SLC29A1;HTR2A;CACNA1I GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1 GO:0045821| positive regulation of glycolysis HTR2A GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;NAAA;GPX1;PTGS1 GO:0007507| heart development HTR2B;PPARG GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 GO:0042310| vasoconstriction HTR2B;SLC6A4;HTR1A GO:0042136| neurotransmitter biosynthetic process SLC6A4;DAGLA GO:0048148| behavioral response to cocaine HTR2A GO:0001659| temperature homeostasis TRPV1;GPX1;HTR2A GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2C;HTR2A GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GLRA1;CACNA1G;HTR2C;VDAC1;GLRB GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;TRPA1 GO:0033674| positive regulation of kinase activity HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0016032| viral reproduction HTR2A;VDAC1 GO:0007568| aging CYP1A1;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0051209| release of sequestered calcium ion into cytosol TRPV1;HTR2B;HTR2C;TRPA1;HTR2A GO:0032355| response to estradiol stimulus CAT;SLC6A4;PTGS2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;HTR2C;HTR2B;GPR18;PPARG GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0006874| cellular calcium ion homeostasis TRPV4;HTR2B;HTR2C;TRPM8;HTR2A;GPR12;CHRNA7 GO:0007210| serotonin receptor signaling pathway HTR2B;HTR2C;HTR2A;HTR1A GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC6A4;GLRA1 GO:0008219| cell death HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;HTR2B;HTR2C;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0055085| transmembrane transport TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;SLC6A4;CACNA1H;TRPV3 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0071502| cellular response to temperature stimulus TRPV1;HTR2B GO:0014059| regulation of dopamine secretion HTR2A GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;SLC6A4;TRPA1;CYP1A1;PPARG GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;HTR2C;GPR18 GO:0043406| positive regulation of MAP kinase activity HTR2B;HTR2A GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;HTR2B GO:0010628| positive regulation of gene expression TRPV4;SLC6A4 GO:0001666| response to hypoxia CYP1A1;SLC6A4;CAT;CHRNA7 GO:0014824| artery smooth muscle contraction HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;HTR2C;HTR2B GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0007623| circadian rhythm AANAT;SLC6A4 GO:0050795| regulation of behavior HTR2A;HTR1A;HTR2B GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0043066| negative regulation of apoptotic process HTR2B;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation HTR2B;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0007626| locomotory behavior HTR2C;SOD1;OPRM1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0044380| protein localization to cytoskeleton HTR2A GO:0042493| response to drug ABCG2;HTR2B;HTR2C;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;SLC6A4;HTR2A;SOD1;CYP1A2;PTGS2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;CYP2D6;DAGLA;FAAH GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2C;HTR2B;HTR2A 18493:[DB14011 DB01819] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01819|Phosphoenolpyruvate aroG;kdsA;ENO3;PCK1;kdsA;SLCO2A1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1;PCK1 GO:0043403| skeletal muscle tissue regeneration ENO3;GPX1 GO:0071320| cellular response to cAMP AANAT;PCK1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PCK1 GO:0014823| response to activity CAT;PCK1 GO:0032868| response to insulin stimulus CAT;AANAT;PCK1;TRPV4 GO:0071300| cellular response to retinoic acid PCK1;PPARG GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PCK1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;TRPA1;ENO3;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2 GO:0033993| response to lipid PCK1;PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;PCK1 GO:0007568| aging CAT;PCK1;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CYP1A1;ENO3 GO:0071456| cellular response to hypoxia SLC29A1;PCK1;PTGS2;OPRD1 GO:0071356| cellular response to tumor necrosis factor PCK1;TRPV1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;SLCO2A1;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8 18494:[DB14011 DB02803] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02803|3-Phenyl-1,2-Propandiol REN common genes common pathways GO:0008217| regulation of blood pressure PPARG;REN;PTGS1;SOD1;PTGS2 GO:0048469| cell maturation REN;PPARG GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;REN;TRPA1;CYP1A1;PPARG GO:0051591| response to cAMP AANAT;REN GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;REN;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0035902| response to immobilization stress REN;PPARG;CYP1A1;CYP1A2 GO:0001822| kidney development REN;CAT GO:0032496| response to lipopolysaccharide CNR2;PTGS2;CYP1A2;OPRM1;CNR1;REN;CYP1A1;IDO1 18495:[DB14011 DB05305] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05305|Cintredekin Besudotox IL13 common genes common pathways GO:0006955| immune response IL13;CNR2;OPRD1 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;IL13;TRPV1;IDO1;ALOX15 GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1;IL13 GO:0001774| microglial cell activation TRPV1;IL13 GO:0071260| cellular response to mechanical stimulus PTGS2;IL13 GO:0071345| cellular response to cytokine stimulus IL13;TRPV1 GO:0035094| response to nicotine CNR1;CHRNA7;IL13 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;IL13 GO:0032496| response to lipopolysaccharide IL13;IDO1;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0009612| response to mechanical stimulus IL13;TRPV4;PPARG GO:0050714| positive regulation of protein secretion PLA2G1B;IL13 18496:[DB14011 DB01871] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01871|[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways 18497:[DB14011 DB06138] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06138|IRL-1620 EDNRB common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration EDNRB;TRPV1;TRPV4;HTR2A;OPRM1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;EDNRB;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0051930| regulation of sensory perception of pain EDNRB;OPRD1;OPRM1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;EDNRB;CYP1A2;PTGS2;AANAT;ACAT1 GO:0008217| regulation of blood pressure EDNRB;PPARG;PTGS1;PTGS2;SOD1 GO:0007166| cell surface receptor linked signaling pathway EDNRB;TRPV1;TRPA1 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1;EDNRB;TRPV1;TRPA1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;EDNRB GO:0007399| nervous system development SMPD1;EDNRB;GLRB GO:0042310| vasoconstriction HTR1A;EDNRB GO:0001934| positive regulation of protein phosphorylation EDNRB;CHRNA7 GO:0007568| aging HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CAT;CYP1A1;EDNRB GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;EDNRB;GPR18;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;EDNRB GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;EDNRB;IDO1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDNRB;TRPV4;TRPV1;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;EDNRB GO:0042311| vasodilation GPX1;EDNRB GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;EDNRB GO:0048265| response to pain EDNRB;TRPV1;TRPA1 18498:[DB14011 DB07235] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07235|N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE PRKACA common genes common pathways GO:0061136| regulation of proteasomal protein catabolic process PRKACA;GPX1 GO:0002027| regulation of heart rate CACNA1G;PRKACA GO:0034605| cellular response to heat PTGS2;PRKACA;TRPV4;TRPV1 GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 18499:[DB14011 DB07963] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways GO:0006810| transport TRPV2;TTR;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process TTR;CYP1B1 18500:[DB14011 DB11491] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11491|Sarafloxacin CYP1A2 common genes CYP1A2 common pathways GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0032259| methylation CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1A1;CYP2C9;CRYZ;GPX1;ALOX5;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0010468| regulation of gene expression CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 18501:[DB14011 DB02635] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways GO:0009083| branched chain family amino acid catabolic process ACAT1;BCAT2 GO:0006550| isoleucine catabolic process ACAT1;BCAT2 GO:0008152| metabolic process BCAT2;SMPD1;ACAT1 18502:[DB14011 DB07467] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07467|4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide CA2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0010033| response to organic substance CA2;TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 GO:0001822| kidney development CA2;CAT 18503:[DB14011 DB06751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;CACNA1C;CACNA1H GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;CACNA1H;OPRM1;TRPV3;CHRNA7;TRPV2;CACNA1C GO:0043010| camera-type eye development CYP1A1;CACNA1C GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;PDE4A;OPRD1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;CACNA1C;HTR2A;OPRM1 GO:0050796| regulation of insulin secretion CACNA1C;CNR1 GO:0006811| ion transport CHRNA7;CACNA1C;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPA1;GLRA1;CACNA1G GO:0086045| CACNA1C;CACNA1G GO:0007507| heart development CACNA1C;PPARG GO:0086091| CACNA1G;CACNA1C GO:0006816| calcium ion transport CACNA1C;TRPV2;CHRNA7;TRPV3;CACNA1H;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;PDE4A;OPRD1;PPARG;GPR18 GO:0086002| CACNA1G;CACNA1C GO:0055085| transmembrane transport TRPV3;CACNA1H;CACNA1C;TRPV2;ABCC1;CACNA1G;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2 18504:[DB14011 DB04926] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04926|Neramexane GRIN3A common genes common pathways GO:0070588| calcium ion transmembrane transport TRPV3;CACNA1H;OPRM1;TRPV2;CHRNA7;CACNA1G;TRPA1;GRIN3A;TRPV1;TRPV4;CACNA1I;TRPM8 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GRIN3A;GLRA1;TRPA1;CACNA1G GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;GRIN3A GO:0006816| calcium ion transport CACNA1G;GRIN3A;TRPA1;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1H;TRPV3;TRPV2;CHRNA7 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;GLRB;TRPV1;GRIN3A;GLRA1;TRPA1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;GLRA1;GRIN3A 18505:[DB14011 DB07132] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;PDPK1 GO:0035556| intracellular signal transduction PLA2G1B;PDPK1 GO:0043524| negative regulation of neuron apoptosis PDPK1;SOD1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PDPK1 GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1 GO:0045766| positive regulation of angiogenesis CHRNA7;PDPK1;CYP1B1 18506:[DB14011 DB01650] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;SLC22A8;TRPV2 GO:0098656| SLC22A8;VDAC1 GO:0006811| ion transport TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;SLC22A8;CACNA1H;TRPV3 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC22A8 18507:[DB14011 DB03928] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03928|Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol CTH common genes common pathways GO:0043066| negative regulation of apoptotic process CTH;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;CTH;PLA2G1B GO:0051289| protein homotetramerization TRPM8;TRPV1;CRYZ;TRPA1;CAT;CTH 18508:[DB14011 DB07006] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07006|9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE WEE1 common genes common pathways 18509:[DB14011 DB01257] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01257|Eculizumab C5 common genes common pathways GO:0000187| activation of MAPK activity SOD1;C5;CHRNA7;PLA2G1B GO:0045766| positive regulation of angiogenesis CYP1B1;C5;CHRNA7 GO:0002376| immune system process IDO1;C5 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GPR12;CNR1;HTR2A;C5;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0060326| cell chemotaxis ABCC1;C5 GO:0045087| innate immune response C5;PPARG GO:0006954| inflammatory response CNR2;PTGS2;C5;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;C5 GO:0010575| positive regulation vascular endothelial growth factor production C5;PTGS2;CYP1B1 18510:[DB14011 DB04392] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04392|Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] NQO1;azoR common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;NQO1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;NQO1 GO:0019430| removal of superoxide radicals NQO1;SOD1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;NQO1 GO:0007584| response to nutrient PPARG;NQO1;HMGCR;CNR1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NQO1 GO:0014070| response to organic cyclic compound TRPA1;NQO1;PPARG;CYP1A1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0009636| response to toxin CAT;GPX1;CYP1A1;NQO1;CYP1B1 GO:0043066| negative regulation of apoptotic process NQO1;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9;NQO1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1;NQO1 GO:0007568| aging NQO1;CYP1A1;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;NQO1 18511:[DB14011 DB03611] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03611|L-2-amino-4-methoxy-cis-but-3-enoic acid MAT1A common genes common pathways GO:0032259| methylation MAT1A;CYP1A2 GO:0051289| protein homotetramerization MAT1A;CRYZ;TRPA1;TRPV1;TRPM8;CAT 18512:[DB14011 DB02825] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;ACHE GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development ACHE;CACNA1H 18513:[DB14011 DB02854] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0016042| lipid catabolic process SULT2A1;NAPEPLD;DAGLA;PLA2G1B GO:0002376| immune system process IGHG2;IDO1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4;SULT2A1 GO:0006694| steroid biosynthetic process HMGCR;HSD17B11;CYP17A1 GO:0055114| oxidation-reduction process CYP1B1;HSD17B11;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP2C9;CYP1A1;CRYZ;ALOX5;PTGS1;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0045087| innate immune response PPARG;IGHG2 GO:0019216| regulation of lipid metabolic process SULT2A1;HMGCR;CNR1;PPARG;CYP1A1 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;HSD17B11;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1;SULT2A1 18514:[DB14011 DB06534] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06534|Thrombopoietin MPL common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;MPL;HTR1A GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;MPL 18515:[DB14011 DB05166] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05166|APD668 GPR119 common genes common pathways GO:0007165| signal transduction HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR119 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;GPR119;PPARG;GPR18 18516:[DB14011 DB12035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12035|Sarecycline ABCB1 common genes common pathways GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1;CACNA1H;TRPV3;TRPV2 GO:0006810| transport TRPV2;ABCC1;ABCG2;ABCB1;CACNA1I;TRPV1 GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;ABCB1;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 18517:[DB14011 DB11577] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0007565| female pregnancy ADRA2B;ADRA2C;IDO1 GO:0006805| xenobiotic metabolic process AHR;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0035556| intracellular signal transduction ADRA1A;PLA2G1B;ADRA1B GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRA1B;CNR1;ADRA1D GO:0006351| transcription, DNA-dependent AHR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AHR GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;ADRA1A;PPARG GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D GO:0045777| positive regulation of blood pressure ADRA2B;CNR1 GO:0009636| response to toxin AHR;CYP1A1;CYP1B1;GPX1;CAT GO:0008283| cell proliferation HTR1A;ADRA1B;GPX1;CYP1A1;ADRA1D GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADRA2C GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0007165| signal transduction ADRA1B;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;ADRA2C;CNR1;GPR12;HTR2A;ADRA2B;PLA2G1B;CACNA1I;ADRA1A;ADRA2A;ADRA1D;SMPD1;PPARG;GPR18 GO:0045907| positive regulation of vasoconstriction ADRA1A;ADRA1D;ADRA1B;PTGS2;HTR2A;ADRA2C GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRM1;OPRD1 GO:0050796| regulation of insulin secretion ADRA2A;ADRA2C;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;ADRA1A;ADRA1D;ADRA1B;HTR2A;OPRM1 GO:0045893| positive regulation of transcription, DNA-dependent AHR;PPARG GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0006355| regulation of transcription, DNA-dependent AHR;PPARG GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ADRA1A;ABCG2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AHR GO:0008284| positive regulation of cell proliferation ADRA2A;ADRA1D;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1B;HTR2A;OPRM1;OPRD1;ADRA1A;ADRA1D GO:0009410| response to xenobiotic stimulus AHR;GPX1 GO:0045892| negative regulation of transcription, DNA-dependent AHR;PPARG GO:0048511| rhythmic process AANAT;PPARG;AHR GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A GO:0007202| activation of phospholipase C activity HTR2A;GPR55;ADRA1A GO:0006915| apoptotic process VDAC1;ADRA1A;AHR;GPX1 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;ADRA2B;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ADRA1A;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0042593| glucose homeostasis ADRA2A;TRPV4;PPARG;ADRA1B;CNR1 GO:0007568| aging CAT;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;ADRA1A;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;AHR GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;ADRA1D;ADRA2A;ADRA1A;ADRA2C;GPR55;HTR1A;ADRA2B;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;ADRA1B 18518:[DB14011 DB04695] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04695|Farnesyl thiopyrophosphate ispU;GGPS1;MVK common genes common pathways GO:0006695| cholesterol biosynthetic process HMGCR;MVK;GGPS1 GO:0008203| cholesterol metabolic process MVK;CAT;HMGCR GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;MVK GO:0050728| negative regulation of inflammatory response CNR2;MVK GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C9;CYP1A1;MVK;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1 GO:0008299| isoprenoid biosynthetic process HMGCR;GGPS1;MVK GO:0045540| regulation of cholesterol biosynthetic process MVK;GGPS1;HMGCR GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG;MVK;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0016126| sterol biosynthetic process HMGCR;MVK 18519:[DB14011 DB12077] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12077|Urelumab TNFRSF9 common genes common pathways GO:0006915| apoptotic process GPX1;TNFRSF9;VDAC1 GO:0042127| regulation of cell proliferation TNFRSF9;PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;TNFRSF9;CYP1A1;IDO1 GO:0070207| protein homotrimerization TNFRSF9;TRPM8 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;TNFRSF9 GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;IDO1;ALOX15;TRPV1;TNFRSF9 GO:0006955| immune response CNR2;OPRD1;TNFRSF9 18520:[DB14011 DB06274] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes OPRM1;OPRD1 common pathways GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1 GO:0071315| cellular response to morphine OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;TRPV3;OPRM1;CACNA1H;TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G GO:0044849| OPRK1;OPRM1 GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;OPRK1;PLA2G1B;CACNA1I GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus CAT;AANAT;OPRK1;TRPV4 GO:0008344| adult locomotory behavior OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CAT;OPRK1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0019233| sensory perception of pain TRPV1;OPRK1;TRPA1;OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2;CAT GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0010629| negative regulation of gene expression OPRD1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;GLRA1;CACNA1G;OPRK1;VDAC1;GLRB GO:0048149| behavioral response to ethanol OPRM1 GO:0006955| immune response CNR2;OPRD1;OPRK1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0007600| sensory perception OPRM1;TRPV2;OPRK1 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18;OPRK1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;ALOX15 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0042220| response to cocaine CNR1;OPRM1;OPRK1;SMPD1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;CNR2;OPRD1;CNR1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;CYP1A1;IDO1 GO:0033554| cellular response to stress OPRM1 GO:0042060| wound healing ALOX15;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;OPRK1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRM1;OPRD1;OPRK1;GLRB;GLRA1 GO:0070848| response to growth factor stimulus OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0032094| response to food OPRM1;CYP1A1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0043278| response to morphine CNR1;OPRM1;OPRK1 18521:[DB14011 DB06977] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06977|(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine PRKACA common genes common pathways GO:0002027| regulation of heart rate CACNA1G;PRKACA GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0071333| cellular response to glucose stimulus SLC29A1;PRKACA GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2;PRKACA 18522:[DB14011 DB05042] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05042|SGS518 HTR6 common genes common pathways GO:0007268| synaptic transmission CACNA1G;GLRA1;GLRB;VDAC1;HTR6;OPRD1;OPRM1;HTR2A;GLRA3 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;HTR6;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR6;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1;HTR6 18523:[DB14011 DB05688] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0048265| response to pain TRPA1;SLC6A2;TRPV1 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;SLC6A4;CAT;CYP1A1;PPARG;TRPA1;SLC6A2;SMPD1;ABCC1;ABCG2 GO:0071300| cellular response to retinoic acid PPARG;SLC6A4 GO:0007623| circadian rhythm AANAT;SLC6A4 GO:0001666| response to hypoxia CAT;SLC6A4;CHRNA7;CYP1A1 GO:0010628| positive regulation of gene expression SLC6A4;TRPV4 GO:0010033| response to organic substance SLC6A4;SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;SLC6A2;CACNA1G;TRPA1;TRPV2;SLC6A4;TRPV3;CACNA1H GO:0051260| protein homooligomerization GLRA1;ACAT1;SLC6A4;GLRA3 GO:0032355| response to estradiol stimulus SLC6A4;CAT;CYP1A2;PTGS2 GO:0006810| transport TRPV2;SLC6A2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0007268| synaptic transmission GLRB;VDAC1;SLC6A2;CACNA1G;GLRA1;OPRD1;OPRM1;GLRA3;HTR2A GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC6A4 GO:0042310| vasoconstriction SLC6A4;HTR1A GO:0007584| response to nutrient PPARG;HMGCR;CNR1;SLC6A4 GO:0009636| response to toxin GPX1;SLC6A4;CAT;CYP1B1;CYP1A1 GO:0007420| brain development ACAT1;SLC6A4 GO:0007613| memory PTGS2;CNR1;HTR2A;SLC6A4;CHRNA7 18524:[DB14011 DB04958] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04958|Epratuzumab CD22 common genes common pathways GO:0007155| cell adhesion CYP1B1;CD22 18525:[DB14011 DB04166] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;IL4I1;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;DAO 18526:[DB14011 DB00047] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG GO:0006355| regulation of transcription, DNA-dependent INSR;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0007612| learning VDAC1;INSR;PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;IGF1R GO:0008284| positive regulation of cell proliferation INSR;CHRNA7;HMGCR;IGF1R;PTGS2;HTR2A;HTR1A GO:0000187| activation of MAPK activity SOD1;CHRNA7;INSR;PLA2G1B GO:0051262| protein tetramerization HMGCR;IGF1R;CAT GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;INSR;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;TRPV1;OPRM1;PTGS2 GO:0042593| glucose homeostasis CNR1;PPARG;INSR;TRPV4 GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 GO:0006955| immune response IGF1R;CNR2;OPRD1 GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0035556| intracellular signal transduction INSR;PLA2G1B GO:0045740| positive regulation of DNA replication IGF1R;INSR;PLA2G1B GO:0007613| memory INSR;CHRNA7;PTGS2;CNR1;HTR2A GO:0032869| cellular response to insulin stimulus INSR;PPARG;PLA2G1B GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;IGF1R GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;IGF1R;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B 18527:[DB14011 DB12890] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12890|Dihydrexidine DRD1 common genes common pathways GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;DRD1;CACNA1H GO:0048148| behavioral response to cocaine DRD1;HTR2A GO:0001659| temperature homeostasis DRD1;GPX1;HTR2A;TRPV1 GO:0008542| visual learning HMGCR;DRD1 GO:0019226| transmission of nerve impulse DRD1;SOD1 GO:0007613| memory CHRNA7;DRD1;CNR1;HTR2A;PTGS2 GO:0001975| response to amphetamine DRD1;SOD1;CNR2 GO:0007165| signal transduction DRD1;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0001662| behavioral fear response HTR1A;DRD1;VDAC1 GO:0042053| regulation of dopamine metabolic process HTR1A;DRD1 GO:0007612| learning VDAC1;PTGS2;DRD1 GO:0007628| adult walking behavior GLRB;GLRA1;DRD1 GO:0042311| vasodilation DRD1;GPX1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;OPRM1 GO:0007626| locomotory behavior DRD1;OPRM1;SOD1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;DRD1;CYP1A2;PTGS2;SOD1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;DRD1;PPARG;GPR18 GO:0006936| muscle contraction DRD1;CACNA1H;GLRA1 GO:0042220| response to cocaine DRD1;OPRM1;CNR1;SMPD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD1;GPR55;GPR18 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;CNR2;OPRM1;DRD1 GO:0010628| positive regulation of gene expression DRD1;TRPV4 18528:[DB14011 DB00130] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0032868| response to insulin stimulus AANAT;CAT;CAD;TRPV4 GO:0015949| nucleobase-containing small molecule interconversion GSR;CTPS1 GO:0009636| response to toxin CYP1A1;CYP1B1;ASNS;SLC7A8;CAT;GPX1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;CTPS1 GO:0006811| ion transport SLC38A3;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0008283| cell proliferation CYP1A1;HTR1A;GLUL;GPX1 GO:0007420| brain development ACAT1;SLC38A3;QARS GO:0032870| cellular response to hormone stimulus CACNA1H;ASNS GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PPAT GO:0046718| entry of virus into host cell SLC1A5;HTR2A GO:0050729| positive regulation of inflammatory response TGM2;TRPV4 GO:0072593| reactive oxygen species metabolic process GLS2;SOD1 GO:0007595| lactation PPAT;SLC29A1;CAD GO:0016032| viral reproduction HTR2A;SLC1A5;VDAC1 GO:0051289| protein homotetramerization CAT;PPAT;GLS;TRPM8;TRPV1;TRPA1;CRYZ GO:0014047| glutamate secretion TRPV1;GLS2;GLS GO:0007565| female pregnancy SLC38A3;IDO1;CAD GO:0031667| response to nutrient levels SOD1;ASNS GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;OPRM1;OPRD1;GLS;HTR2A;GLRA3 GO:0007507| heart development PPARG;CAD GO:0008152| metabolic process PPAT;ACAT1;SMPD1;CAD GO:0043065| positive regulation of apoptotic process SOD1;CNR1;TGM2;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0001889| liver development CAD;CYP1A1;ACAT1;ASNS GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;GLUL GO:0051262| protein tetramerization TGM3;HMGCR;CAT GO:0031000| response to caffeine CAD;PPARG GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;GPR55;TGM2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;QARS GO:0009416| response to light stimulus ASNS;AANAT GO:0043277| apoptotic cell clearance TGM2;ALOX15 GO:0055085| transmembrane transport TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;SLC38A3;CACNA1H;TRPV3;SLC16A10 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLS;GLRA1 GO:0043200| response to amino acid stimulus ASNS;GLRA3;GLRB GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CAD GO:0051260| protein homooligomerization ACAT1;TGM2;GLUL;GLRA3;GLRA1 GO:0031100| organ regeneration PPAT;CAD;PPARG GO:0002376| immune system process IDO1;CTPS1 GO:0006810| transport SLC7A8;TRPV2;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;TGM2 GO:0042493| response to drug PPAT;CAT;CYP1A2;PTGS2;SOD1;HTR2A;PFAS;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;CTPS1;TRPA1 GO:0042594| response to starvation PPARG;CAD;ACAT1 GO:0001822| kidney development PPAT;CAT GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;ASNS;GPX1;CAT GO:0009612| response to mechanical stimulus ASNS;PPARG;TRPV4 GO:0002576| platelet degranulation F13A1;SOD1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;TGM2;OPRM1;OPRD1 GO:0060135| maternal process involved in female pregnancy CNR1;PPAT 18529:[DB14011 DB08413] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08413|METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER IGKC;ALPP common genes common pathways GO:0002376| immune system process IDO1;IGKC GO:0045087| innate immune response PPARG;IGKC GO:0001895| retina homeostasis IGKC;SOD1 GO:0006955| immune response IGKC;CNR2;OPRD1 GO:0008152| metabolic process ACAT1;SMPD1;ALPP 18530:[DB14011 DB00459] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00459|Acitretin RXRA;RARA;RARB;RARG;RXRB;RXRG;RBP1;CYP26A1;ALB common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent RARA;PPARG GO:0001657| ureteric bud development RARA;CAT;RARB GO:0010628| positive regulation of gene expression TRPV4;RARA;RARG GO:0043277| apoptotic cell clearance RARA;ALOX15 GO:0007283| spermatogenesis SOD1;CNR1;RARA GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7;RARA GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR;ALB GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0032355| response to estradiol stimulus CAT;RARA;CYP1A2;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter RXRG;RARB;RXRA;RXRB;PPARG;RARG;RARA GO:0033189| response to vitamin A PPARG;CYP1A1;RARA;CAT GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;CYP26A1;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRB;RXRA;RARB;RXRG;RARA;RARG GO:0045893| positive regulation of transcription, DNA-dependent RARA;RXRA;PPARG GO:0034097| response to cytokine stimulus PTGS2;RARA;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARA;RARG;TRPV4;TRPV1;RARB;PPARG;RXRA GO:0002576| platelet degranulation SOD1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARB;PLA2G1B;RXRG;RXRB;RXRA;PPARG;RARA;RARG GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;RARG;RARA;RARB GO:0071300| cellular response to retinoic acid PPARG;RARA;RARG GO:0043066| negative regulation of apoptotic process RARB;ALB;RARA;GPX1;RARG;CAT;HMGCR;PTGS2;SOD1 GO:0032526| response to retinoic acid PPARG;RXRA;RARG;RARA GO:0008203| cholesterol metabolic process HMGCR;CAT;RXRA GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;RARB;PTGS2;OPRM1;RARA;RARG GO:0055088| lipid homeostasis RBP1;PPARG GO:0001890| placenta development SOD1;PPARG;RXRA GO:0001523| retinoid metabolic process RBP1;NAPEPLD GO:0001895| retina homeostasis ALB;SOD1 GO:0007165| signal transduction RARA;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;RARB;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0043010| camera-type eye development RXRA;CYP1A1;RARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0022008| neurogenesis DAGLA;RARB GO:0019216| regulation of lipid metabolic process RXRA;CYP1A1;PPARG;CNR1;HMGCR GO:0007566| embryo implantation RXRA;PTGS2;SOD1 GO:0051289| protein homotetramerization CAT;TRPA1;RXRA;CRYZ;TRPV1;TRPM8;RXRG GO:0016032| viral reproduction HTR2A;VDAC1;RXRA GO:0007565| female pregnancy IDO1;RARA GO:0010629| negative regulation of gene expression RARA;OPRD1 GO:0007507| heart development RXRA;PPARG GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;RARB;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;RARG GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP26A1;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP26A1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;RARA GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRB;RXRA;RARB;RXRG;RARA;RARG GO:0001889| liver development ACAT1;RARA;CYP1A1 GO:0006351| transcription, DNA-dependent PPARG;RXRB;RXRA;RARB;RXRG;RARA;RARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA 18531:[DB14011 DB14069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14069|ONT-093 ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCB1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG GO:0006810| transport ABCC1;ABCG2;TRPV1;CACNA1I;ABCB1;TRPV2 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;ABCC1 18532:[DB14011 DB07427] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0042542| response to hydrogen peroxide SOD1;GPX1;CAT;HBA1;TRPA1;HBB GO:0010942| positive regulation of cell death HBB;HBA1;PTGS2 GO:0051291| protein heterooligomerization GLRB;HBB;GLRA1;HBA1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;HBB;PPARG GO:0043312| neutrophil degranulation HBB;CAT;ALOX5 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HBB;PTGS2;OPRM1 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;HBA1;HBB 18533:[DB14011 DB03525] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03525|RU79073 SRC common genes common pathways GO:0008283| cell proliferation CYP1A1;SRC;GPX1;HTR1A GO:0045453| bone resorption GPR55;SRC GO:0007165| signal transduction SRC;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;SRC GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0043065| positive regulation of apoptotic process SRC;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0042542| response to hydrogen peroxide CAT;GPX1;SRC;SOD1;TRPA1 GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;SRC GO:0002376| immune system process IDO1;SRC GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042493| response to drug CAT;SRC;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0016236| macroautophagy VDAC1;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0009615| response to virus CYP1A1;SRC GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0043066| negative regulation of apoptotic process SRC;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 18534:[DB14011 DB00117] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1H;TRPV3;SLC16A10;TRPV2;SLC38A3 GO:0006811| ion transport TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;SLC38A3;GLRA3;CACNA1H;TRPV3 GO:0007420| brain development SLC38A3;ACAT1 GO:0007565| female pregnancy SLC38A3;IDO1 18535:[DB14011 DB03976] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03976|Phosphorylisopropane PRSS1;PRSS2;CTRB1;BCHE common genes common pathways GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;BCHE;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0043312| neutrophil degranulation PRSS2;CAT;ALOX5 GO:0009235| cobalamin metabolic process CTRB1;ABCC1;PRSS1 GO:0008285| negative regulation of cell proliferation PPARG;BCHE;CYP1B1;PTGS2;OPRM1 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 18536:[DB14011 DB04472] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;LGALS9 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;LGALS9;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0002376| immune system process IDO1;LGALS9 GO:0032720| negative regulation of tumor necrosis factor production LGALS9;CHRNA7;GPR18 GO:0071636| positive regulation of transforming growth factor beta production PTGS2;LGALS9 GO:0071639| positive regulation of monocyte chemotactic protein-1 production LGALS9;TRPV4 GO:0060135| maternal process involved in female pregnancy LGALS9;CNR1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;LGALS9;PTGS2;CYP1A2;OPRM1 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;LGALS9 GO:0006954| inflammatory response LGALS9;PTGS2;CNR2;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;LGALS9;CAT GO:0007565| female pregnancy LGALS9;IDO1 GO:0010629| negative regulation of gene expression OPRD1;LGALS9 18537:[DB14011 DB06749] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;SLCO1B3;TRPV2 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;SLCO1B3;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 18538:[DB14011 DB00978] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes CYP1A2 common pathways GO:0006979| response to oxidative stress ABCC2;PTGS2;SOD1;GPX1;PTGS1;CAT GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0010468| regulation of gene expression CYP1A2 GO:0006810| transport ABCC2;ABCG2;TRPV1;CACNA1I;ABCC1;TRPV2 GO:0048511| rhythmic process TOP2A;PPARG;AANAT GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;ABCC2;VDAC1;CACNA1I;TRPV4;TRPV1;SLC22A5;CACNA1H;TRPV3;TRPV2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;PLA2G1B GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;CYP1A1;ABCC2;IDO1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0042493| response to drug ABCC2;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0099133| ABCC2;ABCC1 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0006811| ion transport SLC22A5;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;ACAT1;AANAT GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCG2;ABCC2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TOP2A;TRPV1;CYP1B1;IDO1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0009408| response to heat TRPV1;ABCC2;TRPV2;TRPV3;SOD1 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0007565| female pregnancy IDO1;ABCC2 18539:[DB14011 DB06714] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways GO:0001975| response to amphetamine SOD1;SLC18A2;CNR2 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;TAAR1;GPR18;PPARG GO:0009636| response to toxin CYP1A1;CYP1B1;SLC18A2;CAT;GPX1 GO:0009791| post-embryonic development CYP1A2;SLC18A2 GO:0007268| synaptic transmission GLRB;VDAC1;GLRA1;CACNA1G;HTR2A;GLRA3;SLC18A2;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;TAAR1;PPARG;GPR18 GO:0055085| transmembrane transport TRPV1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H;SLC18A2 GO:0007269| neurotransmitter secretion SLC18A2;NAAA GO:0007626| locomotory behavior OPRM1;SLC18A2;SOD1 18540:[DB14011 DB05034] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05034|Ularitide NPR1 common genes common pathways GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1;NPR1 GO:0048662| negative regulation of smooth muscle cell proliferation NPR1;PPARG GO:0035556| intracellular signal transduction NPR1;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;NPR1 GO:0007186| G-protein coupled receptor signaling pathway NPR1;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18 GO:0016525| negative regulation of angiogenesis NPR1;PPARG GO:0030308| negative regulation of cell growth PPARG;NPR1 18541:[DB14011 DB08210] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08210|2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE GCK common genes common pathways GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;GCK GO:0050796| regulation of insulin secretion CNR1;GCK GO:0008152| metabolic process SMPD1;ACAT1;GCK GO:0042593| glucose homeostasis CNR1;GCK;PPARG;TRPV4 GO:0070509| calcium ion import CACNA1H;GCK;TRPV4;CACNA1I;CACNA1G 18542:[DB14011 DB02610] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02610|N-(2,3,4,5,6-Pentaflouro-Benzyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0010033| response to organic substance CA2;CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0001822| kidney development CA2;CAT 18543:[DB14011 DB04929] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04929|DG031 ALOX5AP common genes common pathways GO:0071277| cellular response to calcium ion ALOX5AP;ALOX15 GO:0019370| leukotriene biosynthetic process ALOX5;ALOX5AP;PLA2G1B GO:0070207| protein homotrimerization ALOX5AP;TRPM8 GO:0019372| lipoxygenase pathway ALOX15;ALOX5AP;GPX1;ALOX5;PTGS2 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5AP;ALOX5 GO:0043085| positive regulation of catalytic activity ALOX5AP;SOD1 GO:2001300| ALOX5;ALOX5AP 18544:[DB14011 DB04602] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 18545:[DB14011 DB01561] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01561|Androstanedione HSD17B1 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;HSD17B1;GPX1;NAAA;PTGS1 GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;HSD17B1 GO:0008210| estrogen metabolic process HSD17B1;CYP1B1 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;HSD17B1;ALOX5;GPX1;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1 18546:[DB14011 DB08597] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08597|6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine ACVR1;FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;CACNA1G;FKBP1A;TRPM8;TRPV1;TRPV4;CACNA1I GO:0007507| heart development ACVR1;PPARG GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;TRPV1;FKBP1A GO:0006936| muscle contraction GLRA1;FKBP1A;CACNA1H GO:1902991| FKBP1A;CHRNA7 GO:0031000| response to caffeine PPARG;FKBP1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ACVR1 GO:0045893| positive regulation of transcription, DNA-dependent ACVR1;PPARG 18547:[DB14011 DB07605] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07605|2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 18548:[DB14011 DB08733] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08733|(2R,3R)-N^1^-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N^4^-HYDROXY-2-(2-METHYLPROPYL)-3-{[(1,3-THIAZOL-2-YLCARBONYL)AMINO]METHYL}BUTANEDIAMIDE ADAM28 common genes common pathways GO:0007283| spermatogenesis SOD1;CNR1;ADAM28 18549:[DB14011 DB03917] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways GO:0032526| response to retinoic acid PPARG;RBP4 GO:0030324| lung development RBP4;CYP1A2 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;RBP4 GO:0007507| heart development RBP4;PPARG GO:0042572| retinol metabolic process CYP1B1;RBP4 GO:0045471| response to ethanol CAT;RBP4;SOD1;CNR1;HMGCR;OPRM1 GO:0050896| response to stimulus TRPM8;TRPA1;RBP4 GO:0001523| retinoid metabolic process NAPEPLD;RBP4 GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1;RBP4 18550:[DB14011 DB05290] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05290|SPP 301 EDNRA common genes common pathways GO:0007507| heart development PPARG;EDNRA GO:0042310| vasoconstriction HTR1A;EDNRA GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1;EDNRA GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;EDNRA GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;EDNRA GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;EDNRA GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;EDNRA;PPARG;CACNA1I;PLA2G1B GO:0006939| smooth muscle contraction EDNRA;HTR2A GO:0014824| artery smooth muscle contraction EDNRA;HTR2A GO:0015758| glucose transport EDNRA;PLA2G1B GO:0007202| activation of phospholipase C activity EDNRA;GPR55;HTR2A GO:0001666| response to hypoxia EDNRA;CYP1A1;CHRNA7;CAT GO:0007186| G-protein coupled receptor signaling pathway PPARG;EDNRA;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A 18551:[DB14011 DB09142] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09142|Sincalide SLCO1B3 common genes common pathways GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLCO1B3;VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0006811| ion transport CACNA1H;TRPV3;SLCO1B3;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8 18552:[DB14011 DB04299] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;TRPV1;TRPV4;PPARG GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2;TPR GO:0016032| viral reproduction HTR2A;TPR;VDAC1 GO:0042307| positive regulation of protein import into nucleus PTGS2;TPR GO:0032869| cellular response to insulin stimulus GOT1;PLA2G1B;PPARG GO:0051384| response to glucocorticoid stimulus PTGS2;GOT1 18553:[DB14011 DB00529] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways GO:0050796| regulation of insulin secretion SLC16A1;CNR1 GO:0098656| SLC22A6;VDAC1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;SLC16A1;GPX1;NAAA;PTGS1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0042593| glucose homeostasis TRPV4;PPARG;SLC16A1;CNR1 GO:0055085| transmembrane transport SLC16A1;TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;CACNA1G;SLC22A6;ABCC1 GO:0032094| response to food SLC16A1;OPRM1;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;SLC16A1 18554:[DB14011 DB03807] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PDE4B;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;PPARG;GPR18;PDE4B GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B 18555:[DB14011 DB07194] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways GO:0016032| viral reproduction HTR2A;SYK;VDAC1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;IDO1;ALOX15;TRPV1;SYK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SYK;HTR2A GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B;SYK GO:0035556| intracellular signal transduction PLA2G1B;SYK GO:0001525| angiogenesis CYP1B1;SYK;PTGS2 GO:0007166| cell surface receptor linked signaling pathway SYK;TRPA1;TRPV1 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1;SYK GO:0071404| cellular response to low-density lipoprotein particle stimulus SYK;PPARG GO:0030593| neutrophil chemotaxis SYK;PLA2G1B GO:0045087| innate immune response PPARG;SYK GO:0000187| activation of MAPK activity SYK;PLA2G1B;SOD1;CHRNA7 GO:0002376| immune system process SYK;IDO1 GO:0048514| blood vessel morphogenesis SYK;CYP1B1 18556:[DB14011 DB09108] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09108|Simoctocog Alfa VWF common genes common pathways GO:0007155| cell adhesion CYP1B1;VWF GO:0002576| platelet degranulation VWF;SOD1 GO:0009611| response to wounding CYP1A1;VWF;GPX1 GO:0051260| protein homooligomerization GLRA1;ACAT1;GLRA3;VWF 18557:[DB14011 DB07423] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006351| transcription, DNA-dependent AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;AR;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0008285| negative regulation of cell proliferation AR;PTGS2;OPRM1;CYP1B1;PPARG GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 GO:0007548| sex differentiation CYP17A1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;AR GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;TRPV1;TRPV4;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0006810| transport TRPV2;AR;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0010468| regulation of gene expression CYP1A2;AR GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis AR;SOD1;CNR1 18558:[DB14011 DB02323] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02323|EM-1745 HSD17B1 common genes common pathways GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;GPX1;PTGS1;HSD17B1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;HSD17B1;GPX1;ALOX5;PTGS1 GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;HSD17B1 GO:0008210| estrogen metabolic process CYP1B1;HSD17B1 18559:[DB14011 DB00713] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;SLC15A1;CACNA1G;ABCC1;TRPV2;SLC15A2;CACNA1H;TRPV3 GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;SLC15A1;TRPV2;SLC15A2 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLC15A2;TRPV3;CACNA1H;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;SLC15A1;CACNA1G 18560:[DB14011 DB06984] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06984|(1R,2R,3R,4S,5R)-4-(BENZYLAMINO)-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL MAN2A1 common genes common pathways GO:0050769| positive regulation of neurogenesis OPRM1;MAN2A1 GO:0008152| metabolic process ACAT1;SMPD1;MAN2A1 GO:0001889| liver development ACAT1;MAN2A1;CYP1A1 18561:[DB14011 DB00305] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00305|Mitomycin POR common genes common pathways GO:0070988| demethylation POR;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2C9;POR;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;POR GO:0007584| response to nutrient POR;PPARG;CNR1;HMGCR GO:0019395| fatty acid oxidation PPARG;POR GO:0009812| flavonoid metabolic process CYP1A1;POR GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;POR GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;POR;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0022900| electron transport chain CYP1A2;POR;GSR;IDO1 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;POR;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT 18562:[DB14011 DB02542] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways GO:0061136| regulation of proteasomal protein catabolic process UBB;GPX1 GO:0060612| adipose tissue development UBB;ACAT1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1;UBB GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1;UBB GO:0006879| cellular iron ion homeostasis UBB;SOD1;ABCG2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;UBB;CAT GO:1901214| UBB;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;SOD1;UBB;PLA2G1B GO:0055085| transmembrane transport TRPV2;UBB;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;GLRA3;UBB;CHRNA7 GO:0045087| innate immune response PPARG;UBB GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;UBB GO:0043066| negative regulation of apoptotic process UBB;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;UBB GO:0016236| macroautophagy UBB;VDAC1 18563:[DB14011 DB01047] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0010468| regulation of gene expression CYP1A2;SMO GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;SMO;OPRM1;CNR2;OPRD1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0048741| skeletal muscle fiber development GPX1;SMO GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SMO GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0010628| positive regulation of gene expression SMO;TRPV4 GO:0036378| CYP3A4 GO:0006915| apoptotic process VDAC1;GPX1;NR3C1 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;NR3C1;SMO GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;SMO;NR3C1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;SMO GO:0043066| negative regulation of apoptotic process SOD1;SMO;HMGCR;PTGS2;CAT;GPX1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SMO GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;NR3C1;OPRD1;GPR55;HTR1A;SMO;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0001649| osteoblast differentiation SMO;CAT GO:0001503| ossification ALOX15;SMO GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;PTGS1;GPX1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0042307| positive regulation of protein import into nucleus SMO;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0007166| cell surface receptor linked signaling pathway SMO;TRPV1;TRPA1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0048565| digestive tract development SMO;CYP1A1 GO:0008209| androgen metabolic process CYP3A4 GO:0010629| negative regulation of gene expression SMO;OPRD1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 18564:[DB14011 DB04464] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;S100B;PPARG;SMPD1;UBC;IDO1;TRPV1;CYP1B1 GO:0009409| response to cold TRPM8;TRPA1;PPARG;MT-CO2 GO:0051092| positive regulation of NF-kappaB transcription factor activity UBC;PLA2G1B;CAT GO:0016032| viral reproduction HLA-B;HTR2A;VDAC1 GO:0006955| immune response B2M;CNR2;OPRD1;HLA-B GO:0007595| lactation MT-CO2;SERPINC1;SLC29A1 GO:0006879| cellular iron ion homeostasis ABCG2;UBC;SOD1 GO:0051384| response to glucocorticoid stimulus S100B;PTGS2 GO:0007613| memory S100B;CHRNA7;PTGS2;CNR1;HTR2A GO:0007601| visual perception GLRB;CYP1B1;RABGGTA;GLRA1;CRYZ;RABGGTB GO:0008283| cell proliferation GPX1;S100B;HTR1A;CYP1A1 GO:0045333| cellular respiration CYP1A2;MT-ND1 GO:0014070| response to organic cyclic compound MT-ND1;CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0001895| retina homeostasis SOD1;B2M GO:0061844| B2M;PLA2G1B GO:0007584| response to nutrient PPARG;SERPINC1;CNR1;COX4I1;HMGCR GO:0007611| learning or memory CHRNA7;S100B;CNR1 GO:0008284| positive regulation of cell proliferation CHRNA7;S100B;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;UBC;PPARG GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;UBC GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;UBC;TRPV4;TRPV1 GO:0045087| innate immune response UBC;B2M;PPARG;S100B;HLA-B GO:0043312| neutrophil degranulation ALOX5;CAT;B2M GO:0016236| macroautophagy VDAC1;UBC GO:0050830| defense response to Gram-positive bacterium PLA2G1B;B2M GO:0042493| response to drug ABCG2;MT-ND1;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;B2M;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0022900| electron transport chain MT-CO2;IDO1;GSR;COX7A1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;MT-CO1;MT-ND1;MT-CO2;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0019731| antibacterial humoral response PLA2G1B;B2M GO:0033194| response to hydroperoxide MT-ND1;GPX1 GO:0009060| aerobic respiration MT-CO1;COX6A2;CAT GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1;S100B GO:0007568| aging MT-CO1;CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A GO:0051260| protein homooligomerization GLRA1;GLRA3;CLPP;ACAT1 GO:0002376| immune system process IDO1;B2M;HLA-B GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;MT-CO1 GO:0046686| response to cadmium ion CAT;B2M GO:0034220| ion transmembrane transport UBC;GLRA1;TRPA1;TRPV1;GLRB;GLRA3;CHRNA7 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;UBC;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0000187| activation of MAPK activity UBC;PLA2G1B;SOD1;CHRNA7 GO:0046688| response to copper ion AANAT;SOD1;MT-CO1 GO:0010977| negative regulation of neuron projection development B2M;TRPV4 18565:[DB14011 DB02796] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02796|9-Deazainosine PNP common genes common pathways GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006955| immune response OPRD1;CNR2;PNP GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;PPARG;PNP;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0043312| neutrophil degranulation ALOX5;CAT;PNP 18566:[DB14011 DB02162] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HINT1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7 GO:0006351| transcription, DNA-dependent HINT1;PPARG GO:0006915| apoptotic process VDAC1;HINT1;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;HINT1 18567:[DB14011 DB08374] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 18568:[DB14011 DB04260] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 GO:0042493| response to drug ABCG2;TRPA1;PPARG;PNP;CYP1A1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0006955| immune response CNR2;OPRD1;PNP GO:0006195| purine nucleotide catabolic process GPX1;PNP 18569:[DB14011 DB08357] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development ACHE;CACNA1H GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA 18570:[DB14011 DB00010] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00010|Sermorelin GHRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GHRHR;PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0071333| cellular response to glucose stimulus SLC29A1;GHRHR GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;GHRHR GO:0032868| response to insulin stimulus AANAT;CAT;GHRHR;TRPV4 GO:0043627| response to estrogen stimulus PPARG;GHRHR GO:0051384| response to glucocorticoid stimulus PTGS2;GHRHR GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;GHRHR GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GHRHR;GPR18;SMPD1 GO:0007595| lactation SLC29A1;GHRHR GO:0048469| cell maturation GHRHR;PPARG GO:0007166| cell surface receptor linked signaling pathway GHRHR;TRPA1;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger GHRHR;CNR1 18571:[DB14011 DB08362] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08362|N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1;GPX1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;CSNK2A1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7 GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;CSNK2A1;PTGS2 GO:0048511| rhythmic process PPARG;CSNK2A1;AANAT GO:0006915| apoptotic process GPX1;CSNK2A1;VDAC1 18572:[DB14011 DB02049] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02049|2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide MMP13 common genes common pathways GO:0030282| bone mineralization ALOX15;MMP13;PTGS2 18573:[DB14011 DB08900] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08900|Teduglutide GLP2R common genes common pathways GO:0008284| positive regulation of cell proliferation GLP2R;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GLP2R;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;GLP2R GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger GLP2R;CNR1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;GLP2R;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 18574:[DB14011 DB03523] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03523|Brequinar DHODH common genes common pathways GO:0014070| response to organic cyclic compound AANAT;ACAT1;DHODH;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;DHODH GO:0007565| female pregnancy DHODH;IDO1 GO:0007595| lactation DHODH;SLC29A1 GO:0031000| response to caffeine PPARG;DHODH GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT;DHODH GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ;GPX1;ALOX5;PTGS1;CAT;DHODH;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 18575:[DB14011 DB13167] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13167|Alclofenac PTGS2 common genes PTGS2 common pathways GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain CNR1;HTR2A;PTGS2;CNR2;OPRM1;OPRD1;TRPA1;TRPV1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;PTGS2;CNR2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0007568| aging CYP1A1;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1;CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0009750| response to fructose stimulus PTGS2 18576:[DB14011 DB05941] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05941|Leronlimab CCR5 common genes common pathways GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;CCR5;PPARG;SMPD1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;CCR5;OPRM1;HTR2A GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;CCR5;PTGS1;ALOX5;CNR2;PTGS2 GO:0006955| immune response CCR5;CNR2;OPRD1 GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;CCR5;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1 GO:0016032| viral reproduction HTR2A;CCR5;VDAC1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CCR5 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;GPR18;CCR5;PPARG 18577:[DB14011 DB13929] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13929|Relcovaptan OXTR;AVPR1A common genes common pathways GO:0007507| heart development OXTR;PPARG GO:0030431| sleep HTR2A;OXTR;SLC29A1;CACNA1I GO:0007166| cell surface receptor linked signaling pathway OXTR;TRPA1;TRPV1 GO:0060137| maternal process involved in parturition OXTR;CYP1A1 GO:0048565| digestive tract development OXTR;CYP1A1 GO:0007595| lactation SLC29A1;OXTR GO:0007565| female pregnancy IDO1;OXTR GO:0045907| positive regulation of vasoconstriction HTR2A;OXTR;AVPR1A;PTGS2 GO:0032870| cellular response to hormone stimulus OXTR;AVPR1A;CACNA1H GO:0044849| OXTR;OPRM1 GO:0051412| response to corticosterone stimulus AANAT;AVPR1A GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;OXTR;HTR1A;GPR55;AVPR1A GO:0043434| response to peptide hormone stimulus OXTR;TRPV1 GO:0001975| response to amphetamine CNR2;OXTR;SOD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;AVPR1A;HTR2A;OXTR;TRPV1;TRPV4 GO:0007613| memory PTGS2;OXTR;HTR2A;CNR1;CHRNA7 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;OXTR;CYP1A2;PTGS2;AANAT;ACAT1 GO:0042755| eating behavior OPRD1;OPRM1;OXTR GO:0045777| positive regulation of blood pressure OXTR;CNR1;AVPR1A GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;AVPR1A GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;AVPR1A;HTR2A;PTGS2;HMGCR GO:0034097| response to cytokine stimulus AANAT;PTGS2;OXTR GO:0014902| myotube differentiation GPX1;AVPR1A GO:0051970| negative regulation of transmission of nerve impulse GLRA1;AVPR1A GO:0042493| response to drug CAT;SOD1;HTR2A;OXTR;CYP1A2;PTGS2;ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0006936| muscle contraction CACNA1H;OXTR;GLRA1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;GPR12;CNR1;OXTR;HTR1A;GPR55;AVPR1A;OPRD1;OPRM1;CNR2 GO:0032355| response to estradiol stimulus CAT;OXTR;PTGS2;CYP1A2 GO:0007202| activation of phospholipase C activity HTR2A;AVPR1A;GPR55 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;AVPR1A;SOD1;CYP1A2;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;OXTR GO:0042220| response to cocaine SMPD1;OPRM1;CNR1;OXTR 18578:[DB14011 DB03589] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03589|Alpha-Ketomalonic Acid ME2 common genes common pathways GO:0055114| oxidation-reduction process CAT;ME2;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0022900| electron transport chain ME2;CYP1A2;IDO1;GSR GO:0008152| metabolic process ME2;ACAT1;SMPD1 18579:[DB14011 DB02112] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02112|Zk-806450 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18580:[DB14011 DB00036] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways GO:0031100| organ regeneration PPARG;F7 GO:0032355| response to estradiol stimulus F7;TFPI;CYP1A2;PTGS2;CAT GO:0001666| response to hypoxia F7;CYP1A1;CHRNA7;CAT GO:0010628| positive regulation of gene expression HPN;TRPV4 GO:0045766| positive regulation of angiogenesis CHRNA7;F3;CYP1B1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;HPN;GPX1;CAT GO:0007623| circadian rhythm AANAT;F7 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;TFPI;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade F7;F10;GPX1;F3 GO:0009725| response to hormone stimulus F7;ACAT1 GO:0043627| response to estrogen stimulus PPARG;F7 GO:0006919| activation of caspase activity F3;PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;F7;TRPA1;CYP1A1;PPARG GO:0031667| response to nutrient levels SOD1;F7 18581:[DB14011 DB03449] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03449|N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine NOS2;NOS1 common genes common pathways GO:0033555| multicellular organismal response to stress NOS1;IDO1 GO:0006809| nitric oxide biosynthetic process NOS2;NOS1;CYP1B1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0007520| myoblast fusion NOS1;CACNA1H GO:0045454| cell redox homeostasis GPX1;NOS2;NOS1;GSR GO:0042738| exogenous drug catabolic process NOS1;CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0009408| response to heat NOS1;TRPV1;TRPV3;SOD1;TRPV2 GO:0045776| negative regulation of blood pressure NOS2;NOS1;CNR1 GO:0042136| neurotransmitter biosynthetic process DAGLA;NOS1 GO:0001666| response to hypoxia CYP1A1;NOS1;NOS2;CAT;CHRNA7 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;NOS1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;NOS1;CYP1A1;CYP2C9;NOS2;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;PPARG GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;NOS2;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NOS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;PPARG;PLA2G1B GO:0042311| vasodilation NOS1;GPX1 18582:[DB14011 DB07160] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07160|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE CTSB common genes common pathways GO:0046718| entry of virus into host cell CTSB;HTR2A GO:0043312| neutrophil degranulation CTSB;ALOX5;CAT GO:0046697| decidualization CTSB;PTGS2 GO:0030855| epithelial cell differentiation CTSB;VDAC1;PPARG 18583:[DB14011 DB07567] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;ESR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1;TRPV4;TRPV1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TRPV1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 18584:[DB14011 DB02991] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02991|S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea NOS1 common genes common pathways GO:0042738| exogenous drug catabolic process NOS1;CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0009408| response to heat TRPV2;SOD1;TRPV3;TRPV1;NOS1 GO:0045776| negative regulation of blood pressure CNR1;NOS1 GO:0042136| neurotransmitter biosynthetic process NOS1;DAGLA GO:0033555| multicellular organismal response to stress NOS1;IDO1 GO:0006809| nitric oxide biosynthetic process NOS1;CYP1B1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS1 GO:0007520| myoblast fusion NOS1;CACNA1H GO:0045454| cell redox homeostasis GSR;NOS1;GPX1 GO:0055114| oxidation-reduction process NOS1;CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NOS1 GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0042311| vasodilation GPX1;NOS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NOS1;PPARG GO:0001666| response to hypoxia NOS1;CYP1A1;CHRNA7;CAT GO:0071363| cellular response to growth factor stimulus NOS1;TRPV1;OPRD1;CAT 18585:[DB14011 DB03660] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A 18586:[DB14011 DB06916] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide CYP1A1;NOS2;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;NOS2;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045454| cell redox homeostasis NOS2;GSR;GPX1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 18587:[DB14011 DB12271] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;CPN1 18588:[DB14011 DB02451] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02451|B-nonylglucoside RHO;AQP1;CLPS;PNLIP;MIP;KCNJ3 common genes common pathways GO:0071280| cellular response to copper ion CYP1A1;CYP1A2;AQP1 GO:0043085| positive regulation of catalytic activity SOD1;CLPS GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;RHO;GPR18;PPARG GO:0071456| cellular response to hypoxia AQP1;SLC29A1;PTGS2;OPRD1 GO:0050891| multicellular organismal water homeostasis AQP1;TRPV4 GO:0009416| response to light stimulus RHO;AANAT GO:0016042| lipid catabolic process CLPS;DAGLA;PLA2G1B;PNLIP;NAPEPLD GO:0034220| ion transmembrane transport GLRB;TRPV1;MIP;TRPA1;GLRA1;CHRNA7;GLRA3 GO:0006884| cell volume homeostasis AQP1;TRPV4 GO:0045766| positive regulation of angiogenesis AQP1;CHRNA7;CYP1B1 GO:0055085| transmembrane transport TRPV3;CACNA1H;AQP1;TRPV2;TRPA1;MIP;ABCC1;CACNA1G;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0071300| cellular response to retinoic acid AQP1;PPARG GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;AQP1 GO:0033554| cellular response to stress OPRM1;AQP1 GO:0032094| response to food OPRM1;CYP1A1;CLPS GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;AQP1;CAT GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;KCNJ3 GO:0034644| cellular response to UV PTGS2;AQP1 GO:0007165| signal transduction PPARG;GPR18;RHO;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7 GO:0007601| visual perception RHO;CRYZ;GLRA1;MIP;CYP1B1;GLRB GO:0001523| retinoid metabolic process NAPEPLD;PNLIP;RHO;CLPS GO:0048146| positive regulation of fibroblast proliferation AQP1;PLA2G1B GO:0050896| response to stimulus TRPM8;MIP;TRPA1;RHO GO:0070301| cellular response to hydrogen peroxide AQP1;CYP1B1 GO:0006811| ion transport TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;KCNJ3;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0006629| lipid metabolic process CYP2C9;PPARG;CLPS;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;PNLIP;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;NAAA;PTGS1;GPX1 GO:0071260| cellular response to mechanical stimulus AQP1;PTGS2 GO:0086091| KCNJ3;CACNA1G GO:0051289| protein homotetramerization CAT;TRPV1;TRPM8;CRYZ;MIP;TRPA1 GO:0071320| cellular response to cAMP AQP1;AANAT GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;AQP1;PTGS2 18589:[DB14011 DB03060] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03060|Sri-9662 DHFR common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALOX5;GPX1;PTGS1;CRYZ;DHFR;CYP1A1;CYP2C9;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1 18590:[DB14011 DB01307] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0042593| glucose homeostasis CNR1;INSR;PPARG;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;TRPV1;OPRM1;PTGS2 GO:0098869| ALB;GSR;PTGS2;PTGS1;GPX1;CAT GO:0000187| activation of MAPK activity INSR;PLA2G1B;SOD1;CHRNA7 GO:0007612| learning PTGS2;VDAC1;INSR GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;INSR GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0006355| regulation of transcription, DNA-dependent INSR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;INSR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;INSR GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1;INSR GO:0001895| retina homeostasis SOD1;ALB GO:0045740| positive regulation of DNA replication INSR;PLA2G1B GO:0045821| positive regulation of glycolysis HTR2A;INSR GO:0035556| intracellular signal transduction INSR;PLA2G1B GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 18591:[DB14011 DB02093] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02093|5-Phospho-D-Arabinohydroxamic Acid GPI common genes common pathways GO:0001525| angiogenesis PTGS2;GPI;CYP1B1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;GPI GO:0043524| negative regulation of neuron apoptosis GPI;SOD1 GO:0042593| glucose homeostasis TRPV4;GPI;PPARG;CNR1 GO:0032355| response to estradiol stimulus GPI;PTGS2;CYP1A2;CAT GO:0046686| response to cadmium ion GPI;CAT GO:0035902| response to immobilization stress CYP1A2;GPI;CYP1A1;PPARG GO:0043312| neutrophil degranulation GPI;CAT;ALOX5 GO:0007611| learning or memory CHRNA7;CNR1;GPI GO:0043278| response to morphine OPRM1;CNR1;GPI 18592:[DB14011 DB01571] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes OPRD1;OPRM1 common pathways GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0007165| signal transduction PPARG;GPR18;SMPD1;OPRK1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0070588| calcium ion transmembrane transport TRPM8;TRPV1;CACNA1I;TRPV4;TRPA1;CACNA1G;CHRNA7;TRPV2;OPRM1;CACNA1H;TRPV3 GO:0044849| OPRM1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV4;TRPV1 GO:0071315| cellular response to morphine OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0032868| response to insulin stimulus AANAT;CAT;OPRK1;TRPV4 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0009314| response to radiation CAT;PTGS2;OPRM1;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPV1;OPRK1;TRPA1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;OPRK1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0007600| sensory perception TRPV2;OPRM1;OPRK1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0006955| immune response OPRK1;CNR2;OPRD1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission GLRA1;CACNA1G;OPRK1;GLRB;VDAC1;GLRA3;HTR2A;OPRM1;OPRD1 GO:0010629| negative regulation of gene expression OPRD1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRK1;PPARG;GPR18 GO:0071363| cellular response to growth factor stimulus TRPV1;OPRD1;CAT GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0042220| response to cocaine SMPD1;OPRK1;CNR1;OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0050769| positive regulation of neurogenesis OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007626| locomotory behavior OPRM1;SOD1;OPRK1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRD1;OPRM1;GLRA1;OPRK1;GLRB GO:0070848| response to growth factor stimulus OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;OPRK1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0042060| wound healing OPRM1;ALOX15 GO:0043278| response to morphine OPRM1;CNR1;OPRK1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0032094| response to food CYP1A1;OPRM1 18593:[DB14011 DB03367] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03367|PF-00356231 MMP12 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;MMP12 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MMP12 GO:0042060| wound healing OPRM1;MMP12;ALOX15 18594:[DB14011 DB00336] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00336|Nitrofural gor;mdh;XDH common genes common pathways GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0010629| negative regulation of gene expression XDH;OPRD1 GO:0007595| lactation SLC29A1;XDH GO:0006919| activation of caspase activity PPARG;XDH GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;HMGCR;XDH;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0022900| electron transport chain CYP1A2;XDH;GSR;IDO1 18595:[DB14011 DB02143] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02143|N-Isopropyl-N'-Hydroxyguanidine NOS1 common genes common pathways GO:0007520| myoblast fusion CACNA1H;NOS1 GO:0045454| cell redox homeostasis GSR;NOS1;GPX1 GO:0033555| multicellular organismal response to stress NOS1;IDO1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS1 GO:0043267| negative regulation of potassium ion transport NOS1;HTR2A GO:0042136| neurotransmitter biosynthetic process NOS1;DAGLA GO:0045776| negative regulation of blood pressure CNR1;NOS1 GO:0009408| response to heat NOS1;TRPV1;SOD1;TRPV3;TRPV2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;NOS1;CYP2C19 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;NOS1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;NOS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NOS1;PLA2G1B GO:0042311| vasodilation NOS1;GPX1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;NOS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NOS1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 18596:[DB14011 DB02689] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02689|S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine ARG1 common genes common pathways GO:0010269| response to selenium ion ARG1;GPX1 GO:0010043| response to zinc ion ARG1;AANAT GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;ARG1 GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0043434| response to peptide hormone stimulus ARG1;TRPV1 GO:0009635| response to herbicide ARG1;CYP1A1 GO:0007565| female pregnancy IDO1;ARG1 GO:0048678| response to axon injury ARG1;SOD1 GO:0001889| liver development CYP1A1;ACAT1;ARG1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ARG1 GO:0046686| response to cadmium ion ARG1;CAT GO:0042130| negative regulation of T cell proliferation IDO1;ARG1 GO:0009611| response to wounding CYP1A1;GPX1;ARG1 GO:0007568| aging CYP1A1;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CAT;ARG1 GO:0002376| immune system process IDO1;ARG1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT;ARG1 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT;ARG1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E CAT;ARG1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;ARG1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0030324| lung development ARG1;CYP1A2 GO:0070207| protein homotrimerization TRPM8;ARG1 GO:0043312| neutrophil degranulation ALOX5;ARG1;CAT GO:0045087| innate immune response ARG1;PPARG 18597:[DB14011 DB08737] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;ESR1;GPR12;CNR1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1;TRPV4;TRPV1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 18598:[DB14011 DB07390] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07390|2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YL)-UREIDO]-N-METHYL-3-PHENYL-PROPIONAMIDE MMP3 common genes common pathways 18599:[DB14011 DB04343] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways GO:0055085| transmembrane transport TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1;SLC16A3;TRPA1;ABCC1;CACNA1G;TRPV2;TRPV3;CACNA1H 18600:[DB14011 DB04478] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;SORD;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;SORD;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0030317| sperm motility CACNA1I;SORD GO:0046686| response to cadmium ion SORD;CAT GO:0046688| response to copper ion AANAT;SORD;SOD1 GO:0031667| response to nutrient levels SOD1;SORD GO:0006970| response to osmotic stress TRPV4;SORD GO:0009725| response to hormone stimulus ACAT1;SORD 18601:[DB14011 DB00324] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0006915| apoptotic process NR3C1;GPX1;VDAC1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;TRPV1;TRPV4;PPARG GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0007165| signal transduction HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;NR3C1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;NAAA;PTGS1;GPX1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 18602:[DB14011 DB01955] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01955|1,4-Butanediol MAN1B1;PLA2G2A;PLA2G2E common genes common pathways GO:0036150| PLA2G2A;PLA2G2E;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G2A;PLA2G1B;PLA2G2E GO:0050729| positive regulation of inflammatory response PLA2G2A;TRPV4 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PLA2G2E;CNR2;PTGS2;PTGS1;ALOX5 GO:0008152| metabolic process SMPD1;ACAT1;MAN1B1 GO:0036148| PLA2G1B;PLA2G2E;PLA2G2A GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G2A;PLA2G2E;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;PTGS1;GPX1 GO:0036149| PLA2G1B;PLA2G2E;PLA2G2A GO:0006644| phospholipid metabolic process PLA2G2A;PLA2G2E;PLA2G1B;NAPEPLD GO:0016042| lipid catabolic process PLA2G2E;PLA2G1B;DAGLA;PLA2G2A;NAPEPLD GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;PLA2G2A;ALOX15 GO:0036152| PLA2G2A;PLA2G2E;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G2A;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2E;PLA2G2A GO:0036151| PLA2G2A;PLA2G1B;PLA2G2E 18603:[DB14011 DB07380] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process CTRB1;ABCC1 18604:[DB14011 DB02067] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways GO:0051262| protein tetramerization CAT;SHMT1;HMGCR GO:0051289| protein homotetramerization SHMT1;CAT;TRPA1;CRYZ;TRPV1;TRPM8 18605:[DB14011 DB02429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02429|4-(Aminosulfonyl)-N-[(4-Fluorophenyl)Methyl]-Benzamide CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance CA2;TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 18606:[DB14011 DB03341] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes AANAT common pathways GO:0032868| response to insulin stimulus AANAT;CAT;TRPV4 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0010043| response to zinc ion AANAT GO:0051412| response to corticosterone stimulus AANAT GO:0046219| indolalkylamine biosynthetic process AANAT GO:0071320| cellular response to cAMP AANAT GO:0051592| response to calcium ion AANAT GO:0051591| response to cAMP AANAT GO:0048511| rhythmic process AANAT;PPARG GO:0009416| response to light stimulus AANAT GO:0046688| response to copper ion SOD1;AANAT GO:0030187| melatonin biosynthetic process AANAT GO:0034695| response to prostaglandin E stimulus AANAT GO:0009648| photoperiodism AANAT GO:0006474| N-terminal protein amino acid acetylation AANAT GO:0007623| circadian rhythm AANAT GO:0034097| response to cytokine stimulus PTGS2;AANAT 18607:[DB14011 DB02477] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02477|[Cyclohexylethyl]-[[[[4-[2-Methyl-1-Imidazolyl-Butyl]Phenyl]Acetyl]-Seryl]-Lysinyl]-Amine NMT1 common genes common pathways 18608:[DB14011 DB05072] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05072|AV608 TACR1 common genes common pathways GO:0008217| regulation of blood pressure PPARG;PTGS1;TACR1;PTGS2;SOD1 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0045777| positive regulation of blood pressure CNR1;TACR1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;TACR1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0042755| eating behavior OPRM1;TACR1;OPRD1 GO:0009725| response to hormone stimulus ACAT1;TACR1 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;TACR1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0045907| positive regulation of vasoconstriction TACR1;PTGS2;HTR2A GO:0043117| positive regulation of vascular permeability TRPV4;TACR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;TACR1;OPRM1 GO:0060083| smooth muscle contraction involved in micturition TACR1;TRPV1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;TACR1;CNR2;PTGS2;ALOX5;PTGS1 GO:0009408| response to heat TRPV1;TRPV2;TRPV3;TACR1;SOD1 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;TACR1;OPRM1;OPRD1;GLRA3;HTR2A GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;OPRD1;OPRM1;PTGS2;CNR2;TACR1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;TACR1;OPRM1;CAT GO:0048266| behavioral response to pain TACR1;TRPV1 GO:0010193| response to ozone TACR1;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;TACR1;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0032355| response to estradiol stimulus CYP1A2;TACR1;PTGS2;CAT GO:0035094| response to nicotine CHRNA7;TACR1;CNR1 GO:0043278| response to morphine TACR1;OPRM1;CNR1 GO:0048265| response to pain TRPA1;TRPV1;TACR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;TACR1;HTR2A GO:0007611| learning or memory CNR1;TACR1;CHRNA7 18609:[DB14011 DB02648] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways GO:0006631| fatty acid metabolic process ALOX15;CRAT;PTGS2;CROT;PTGS1 GO:0006635| fatty acid beta-oxidation ACAT1;CROT GO:0015936| coenzyme A metabolic process HMGCR;CROT;ACAT1 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;CRAT;NAPEPLD;NAAA;CROT;PTGS1;GPX1 18610:[DB14011 DB06406] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06406|Idraparinux F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 18611:[DB14011 DB02583] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;DHFR;CRYZ;CYP1A1;CYP2C9;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 18612:[DB14011 DB01727] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01727|Isocitric Acid icd;icd;ACO2;IDH2;IDH1 common genes common pathways GO:0006749| glutathione metabolic process IDH1;GSR;SOD1;GPX1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;IDH1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0008152| metabolic process SMPD1;ACO2;ACAT1 GO:0001889| liver development ACAT1;CYP1A1;ACO2 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2;IDH1 GO:0035900| response to isolation stress ACO2;NAPEPLD GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP2C9;CYP1A1;IDH1;IDH2;CRYZ GO:0043312| neutrophil degranulation IDH1;CAT;ALOX5 18613:[DB14011 DB04629] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04629|Aplyronine A ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 GO:0010628| positive regulation of gene expression ACTA1;TRPV4 GO:0048741| skeletal muscle fiber development GPX1;ACTA1 GO:0006936| muscle contraction CACNA1H;ACTA1;GLRA1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;ACTA1 18614:[DB14011 DB04230] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 18615:[DB14011 DB02078] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways GO:0070301| cellular response to hydrogen peroxide CYP1B1;PPIF GO:1904645| CHRNA7;FYN GO:0065009| regulation of molecular function TRPV1;FYN GO:0033138| positive regulation of peptidyl-serine phosphorylation PFN2;PTGS2;OPRD1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;PPIF GO:0006816| calcium ion transport CHRNA7;TRPV2;TRPV3;CACNA1H;TRPM8;CACNA1I;TRPV4;TRPV1;TRPA1;FYN;CACNA1G GO:0016032| viral reproduction HTR2A;VDAC1;FYN GO:0010976| positive regulation of neuron projection development FYN;CNR1 GO:0010629| negative regulation of gene expression FYN;OPRD1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;FYN;TRPA1 GO:0043524| negative regulation of neuron apoptosis FYN;SOD1 GO:0035556| intracellular signal transduction PLA2G1B;FYN GO:0007166| cell surface receptor linked signaling pathway TRPV1;FYN;TRPA1 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;SOD1;CNR1;FYN GO:0071277| cellular response to calcium ion ALOX15;PPIF GO:0006915| apoptotic process PPIF;GPX1;VDAC1 GO:0006979| response to oxidative stress CAT;PPIF;GPX1;PTGS1;SOD1;PTGS2 GO:0002376| immune system process IDO1;FYN GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;FYN GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FYN;CAT GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FYN GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;FYN;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0043066| negative regulation of apoptotic process GPX1;PPIF;CAT;PTGS2;HMGCR;SOD1 GO:0045087| innate immune response PPARG;FYN GO:0030838| positive regulation of actin filament polymerization ALOX15;PFN2 GO:0007612| learning PTGS2;VDAC1;FYN GO:0042127| regulation of cell proliferation FYN;PTGS2;PTGS1 18616:[DB14011 DB01942] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0008219| cell death HMOX1;HTR2A GO:0045766| positive regulation of angiogenesis CHRNA7;HMOX1;FGF1;CYP1B1 GO:0006915| apoptotic process VDAC1;HMOX1;GPX1 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;FGF1;SOD1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;SLC16A3;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2 GO:0001666| response to hypoxia NOS1;CYP1A1;HMOX1;CAT;CHRNA7 GO:0045892| negative regulation of transcription, DNA-dependent CTBP1;PPARG GO:0010033| response to organic substance CA2;CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF1 GO:0034605| cellular response to heat TRPV4;TRPV1;FGF1;HMOX1;PTGS2 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;NOS1;TRPV1 GO:0097112| gamma-aminobutyric acid receptor clustering GLRB;GPHN GO:0071456| cellular response to hypoxia PTGS2;OPRD1;HMOX1;SLC29A1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;HMOX1 GO:0051260| protein homooligomerization GLRA1;ACAT1;HMOX1;GLRA3 GO:0045893| positive regulation of transcription, DNA-dependent NOS1;PPARG GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 GO:0006355| regulation of transcription, DNA-dependent CTBP1;PPARG GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;CTBP1;HMGCR;CYP3A4;HMOX1;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C9;CYP1A1;NOS1;CRYZ;GPHN GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;HMGCR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGF1 GO:0035094| response to nicotine HMOX1;CNR1;CHRNA7 GO:0007269| neurotransmitter secretion NAAA;CASK GO:0070509| calcium ion import CACNA1H;TRPV4;CACNA1I;CASK;CACNA1G GO:0030324| lung development CYP1A2;FGF1 GO:0042311| vasodilation GPX1;NOS1 GO:0001822| kidney development CA2;CAT GO:0008284| positive regulation of cell proliferation FGF1;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CASK;PPARG;NOS1;PLA2G1B;FGF1 GO:0007155| cell adhesion CASK;CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;CTBP1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS1 GO:0008283| cell proliferation GPX1;HTR1A;FGF1;CYP1A1 GO:0033555| multicellular organismal response to stress IDO1;NOS1 GO:0006809| nitric oxide biosynthetic process NOS1;CYP1B1 GO:0010043| response to zinc ion CA2;AANAT GO:0051781| positive regulation of cell division FGF1;CAT GO:0071276| cellular response to cadmium ion SOD1;HMOX1;CYP1A2 GO:0008217| regulation of blood pressure PTGS1;SOD1;HMOX1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation HMOX1;CTBP1;OPRM1;PTGS2;CYP1B1;PPARG GO:1902042| GPX1;HMOX1 GO:0090280| positive regulation of calcium ion import CASK;TRPV2;TRPV3 GO:0043627| response to estrogen stimulus HMOX1;PPARG;CA2 GO:0045454| cell redox homeostasis GSR;NOS1;GPX1 GO:0007520| myoblast fusion NOS1;CACNA1H GO:0048662| negative regulation of smooth muscle cell proliferation HMOX1;PPARG GO:0065009| regulation of molecular function CYTH2;TRPV1 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;FGF1;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0043524| negative regulation of neuron apoptosis SOD1;HMOX1 GO:0042738| exogenous drug catabolic process CYP2C19;NOS1;CYP2C9;CYP1A2;CYP3A4 GO:0001934| positive regulation of protein phosphorylation CHRNA7;FGF1 GO:0016032| viral reproduction CTBP1;HTR2A;VDAC1 GO:0009408| response to heat TRPV1;NOS1;TRPV2;SOD1;TRPV3 GO:1904706| PPARG;HMOX1 GO:0006879| cellular iron ion homeostasis SOD1;HMOX1;ABCG2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0050872| white fat cell differentiation PPARG;CTBP1 GO:0061045| negative regulation of wound healing CASK;HMGCR GO:0006351| transcription, DNA-dependent PPARG;CTBP1 GO:0001525| angiogenesis HMOX1;FGF1;PTGS2;CYP1B1 GO:0045776| negative regulation of blood pressure NOS1;CNR1 GO:0042136| neurotransmitter biosynthetic process NOS1;DAGLA GO:0035556| intracellular signal transduction PLA2G1B;HMOX1 GO:0008152| metabolic process CTBP1;ACAT1;SMPD1;GPHN GO:0042542| response to hydrogen peroxide SOD1;HMOX1;CAT;GPX1;TRPA1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;HMOX1;SOD1;CNR1 18617:[DB14011 DB07796] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07796|(3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18;F2 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 18618:[DB14011 DB08447] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways GO:0036152| PLA2G1B;PLA2G2E GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G2E;PLA2G1B GO:0016042| lipid catabolic process NAPEPLD;DAGLA;PLA2G1B;PLA2G2E GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2E GO:0036151| PLA2G2E;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2E GO:0036150| PLA2G1B;PLA2G2E GO:0036148| PLA2G2E;PLA2G1B GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;PLA2G2E;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9 GO:0036149| PLA2G2E;PLA2G1B GO:0006954| inflammatory response IDO1;ALOX15;PLA2G2E;TRPV1;PTGS1;ALOX5;PTGS2;CNR2 18619:[DB14011 DB08258] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;EPHX2;GPR12;HTR2A GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;EPHX2 GO:0010628| positive regulation of gene expression EPHX2;TRPV4 GO:0019373| epoxygenase P450 pathway EPHX2;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0072593| reactive oxygen species metabolic process SOD1;EPHX2 GO:0009636| response to toxin CYP1A1;CYP1B1;EPHX2;CAT;GPX1 GO:0008217| regulation of blood pressure PTGS1;EPHX2;SOD1;PTGS2;PPARG GO:0008152| metabolic process ACAT1;EPHX2;SMPD1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;EPHX2;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;EPHX2;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS1;ALOX5;CNR2;PTGS2;EPHX2 18620:[DB14011 DB13508] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13508|Cloranolol CYP2D6 common genes CYP2D6 common pathways GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0051100| negative regulation of binding CYP2D6 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 18621:[DB14011 DB03056] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03056|4-Piperidino-Piperidine CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CES1;CYP3A4;PTGS1 GO:0008152| metabolic process ACAT1;CES1;SMPD1 GO:0009636| response to toxin CES1;GPX1;CAT;CYP1A1;CYP1B1 GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0030855| epithelial cell differentiation VDAC1;PPARG;CES1 18622:[DB14011 DB01007] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes CYP2C19;CYP3A4 common pathways GO:0016126| sterol biosynthetic process CYP51A1;HMGCR GO:0016125| sterol metabolic process CYP19A1;CYP17A1;CYP1B1;CYP51A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP1B1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP51A1;CYP1A2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0045471| response to ethanol CAT;CNR1;SOD1;CYP2E1;HMGCR;OPRM1 GO:0070988| demethylation CYP51A1;CYP1A1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP2C9;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C8;CYP2D6;CYP3A5;CYP2C9 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2C8;CYP1A2 GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP1B1;CYP2C9;CYP1A1;CYP2E1;CYP1A2 GO:0008203| cholesterol metabolic process CAT;CYP51A1;HMGCR GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0006695| cholesterol biosynthetic process CYP51A1;HMGCR GO:0010243| response to organic nitrogen TRPV1;PTGS2;CYP2E1 GO:0006694| steroid biosynthetic process HMGCR;CYP51A1;CYP17A1;CYP19A1 GO:0042493| response to drug CYP2E1;SOD1;HTR2A;CYP1A2;PTGS2;CAT;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0022900| electron transport chain CYP19A1;GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;PTGS2;CYP51A1;CYP3A7;HMGCR;CYP2E1;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2C8;CYP2D6;CYP1A1;CYP2C9;CYP19A1;CRYZ GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2C8;CYP2D6;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP51A1;CYP3A7;HMGCR GO:0010193| response to ozone CAT;CYP2E1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0002933| CYP1A1;CYP2C8;CYP3A5;CYP3A7;CYP3A4 GO:0036378| CYP3A4 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;CYP51A1 18623:[DB14011 DB00513] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways GO:0002576| platelet degranulation PLG;SOD1 GO:0051702| interaction with symbiont PLG;GPX1 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;AOX1;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0022900| electron transport chain AOX1;GSR;IDO1;CYP1A2 GO:0017144| drug metabolic process AOX1;CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0001666| response to hypoxia CYP1A1;PLAT;CAT;CHRNA7 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;PTGS1;NAAA;GPX1;HMGCR;LPA;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;PLG 18624:[DB14011 DB03964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03964|4-Hydroxy-Aconitate Ion ACO2 common genes common pathways GO:0035900| response to isolation stress ACO2;NAPEPLD GO:0008152| metabolic process ACAT1;ACO2;SMPD1 GO:0001889| liver development ACAT1;CYP1A1;ACO2 18625:[DB14011 DB09481] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0051262| protein tetramerization TRPM7;HMGCR;CAT;TRPM6 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN1 GO:0055085| transmembrane transport TRPV2;TRPM6;CACNA1H;SLC41A3;TRPM7;TRPV3;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;TRPA1;CACNA1G;ABCC1 GO:0034220| ion transmembrane transport GLRA1;TRPA1;GRIN3A;TRPV1;GLRB;GRIN3B;GLRA3;CHRNA7 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;GRIN2C;GRIN2A;GRIN1;CACNA1H GO:0006874| cellular calcium ion homeostasis GRIN1;GPR12;HTR2A;CHRNA7;TRPV4;TRPM8 GO:0006810| transport GRIN2B;TRPV2;GRIN2A;ABCC1;GRIN2C;TRPV1;CACNA1I;ABCG2 GO:0009611| response to wounding GPX1;GRIN2A;GRIN2C;CYP1A1 GO:0043278| response to morphine CNR1;OPRM1;GRIN1 GO:0050905| neuromuscular process GLRA1;GLRB;GRIN1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;GRIN2A;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PPARG;PLA2G1B GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GRIN3B;GLRB;GRIN2C;GRIN3A;GLRA1;SLC29A1;CHRNA7;GRIN2A;OPRM1;GRIN2D;GRIN1;GRIN2B;GLRA3 GO:0007611| learning or memory CHRNA7;GRIN2A;GRIN2B;CNR1;GRIN1 GO:0043523| regulation of neuron apoptosis GRIN1;GPX1 GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B;GRIN1 GO:0007612| learning VDAC1;PTGS2;GRIN1;GRIN2A GO:0006812| cation transport TRPM8;SLC41A3;TRPM7;GRIN1;TRPM6 GO:0008344| adult locomotory behavior GRIN1;GRIN2D;OPRD1 GO:0009636| response to toxin GPX1;TRPM6;CAT;CYP1B1;CYP1A1 GO:0051930| regulation of sensory perception of pain OPRM1;GRIN2D;OPRD1;GRIN2A GO:0006811| ion transport CACNA1I;GRIN3B;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;GRIN2C;GLRA1;TRPA1;GRIN3A;TRPM6;TRPV2;GRIN2A;CHRNA7;TRPV3;GRIN1;TRPM7;GRIN2D;CACNA1H;GLRA3;CNNM2;GRIN2B GO:0065009| regulation of molecular function TRPV1;GRIN2C;GRIN2A;GRIN1;GRIN2D;GRIN2B GO:1900273| CHRNA7;GRIN2A GO:0070588| calcium ion transmembrane transport TRPV1;TRPV4;GRIN3B;CACNA1I;TRPM8;CACNA1G;TRPA1;GRIN3A;TRPV2;TRPM6;CHRNA7;TRPV3;OPRM1;CACNA1H;TRPM7 GO:0022008| neurogenesis DAGLA;GRIN2A GO:0043576| regulation of respiratory gaseous exchange GLRA1;GRIN1 GO:0007613| memory CHRNA7;GRIN2A;HTR2A;CNR1;GRIN1;PTGS2 GO:0001975| response to amphetamine GRIN2A;GRIN1;CNR2;SOD1 GO:0008542| visual learning GRIN2A;GRIN1;HMGCR GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:0006816| calcium ion transport TRPM7;GRIN1;CACNA1H;TRPV3;GRIN2A;CHRNA7;TRPM6;TRPV2;GRIN3A;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1 GO:0001964| startle response GRIN2A;GRIN2D;GRIN1;GLRB;GLRA1 GO:0043524| negative regulation of neuron apoptosis GRIN1;SOD1 GO:0007268| synaptic transmission VDAC1;GLRB;CACNA1G;GLRA1;GRIN2A;OPRM1;OPRD1;GRIN2B;HTR2A;GLRA3 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GRIN2A GO:0042428| serotonin metabolic process GRIN2A;HTR1A GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;GRIN1;GRIN2A;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRM1;PTGS2;CNR2;GRIN1;OPRD1;CNR1;HTR2A;GRIN2A GO:0030431| sleep GRIN2A;SLC29A1;HTR2A;CACNA1I GO:0045471| response to ethanol GRIN3A;CAT;GRIN2A;GRIN2B;CNR1;SOD1;GRIN1;OPRM1;HMGCR 18626:[DB14011 DB07666] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CAT;CHRNA7;DPP4;CYP1A1 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A 18627:[DB14011 DB04237] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways GO:0008152| metabolic process AMY1A;ACAT1;SMPD1 18628:[DB14011 DB03115] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;MAP2K1;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;MAP2K1;PPARG;CYP1B1 GO:0007507| heart development PPARG;MAP2K1 GO:0010629| negative regulation of gene expression MAP2K1;OPRD1 GO:0048538| thymus development SOD1;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;TRPV4 GO:0000187| activation of MAPK activity MAP2K1;CHRNA7;SOD1;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;MAP2K1;GPR55;HTR2A;OPRM1;HMGCR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;MAP2K1 18629:[DB14011 DB03924] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03924|5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone CSNK2A1 common genes common pathways GO:0006915| apoptotic process VDAC1;GPX1;CSNK2A1 GO:0048511| rhythmic process AANAT;CSNK2A1;PPARG GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;CSNK2A1;HMGCR;CHRNA7 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;CSNK2A1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CSNK2A1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 18630:[DB14011 DB02489] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02489|9-Methylguanine folB;CYP1A2 common genes CYP1A2 common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0045333| cellular respiration CYP1A2 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9;ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CYP1A1;IDO1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT 18631:[DB14011 DB13746] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes CYP3A4;CACNA1G;CACNA1I;CYP2C9;CACNA1H;CYP2C19 common pathways GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008219| cell death HTR2A;CACNA1A GO:0086002| CACNA1C;CACNA1D;CACNA1G GO:0036378| CYP3A4 GO:0055085| transmembrane transport CACNA1H;TRPV3;CACNA1D;TRPV2;CACNA1C;CACNA1S;CACNA1G;ABCC1;TRPA1;CACNA1I;TRPV4;VDAC1;CACNA1A;TRPV1;CACNA1F;ABCG2;TRPM8 GO:0002933| CYP1A1;CYP2C8;CYP3A5;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C8;CYP2C19;CYP2D6 GO:0007605| sensory perception of sound SOD1;CACNA1D;GPX1 GO:0042391| regulation of membrane potential CACNA1H;CACNA1G;GLRA1;GLRB GO:0006936| muscle contraction GLRA1;CACNA1S;CACNA1H GO:0006810| transport ABCC1;CACNB3;CACNA1I;TRPV1;CACNB1;ABCG2;CACNB4;TRPV2 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP17A1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0086027| CACNA1G GO:0086018| CACNA1G GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP2C9;CYP1A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C8;CYP3A5;ALOX15;CYP17A1;CYP1B1 GO:0032342| aldosterone biosynthetic process CACNA1H GO:0007517| muscle organ development CACNA1H GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP1A2 GO:0086015| CACNA1G GO:0010045| response to nickel cation CACNA1G GO:0030317| sperm motility CACNA1I GO:0070509| calcium ion import CACNA1G;TRPV4;CACNA1I;CACNB2;CACNA1H;CACNA1D GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0086016| CACNA1G GO:0001508| regulation of action potential GLRA1;CACNA1G GO:0035865| cellular response to potassium ion SOD1;CACNA1H GO:0086046| CACNA1D;CACNA1G GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G GO:0050896| response to stimulus TRPM8;CACNA1F;TRPA1 GO:0019627| urea metabolic process CYP2C9 GO:0086045| CACNA1C;CACNB2;CACNA1G GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;CACNB2;CACNA1C;CACNA1D;TRPV2;CACNB4;CHRNA7;CACNA1S;CACNA1G;CACNB3;TRPA1;GLRA1;CACNA1F;VDAC1;CACNA1I;TRPV4;GLRB;CACNA1A;TRPV1;TRPM8;CACNB1 GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2C8;CYP1A2 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CACNA1I;CACNA1G GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0043010| camera-type eye development CACNA1C;CYP1A1 GO:1904645| CHRNA7;CACNA1A GO:0032870| cellular response to hormone stimulus CACNA1H GO:0070588| calcium ion transmembrane transport CACNA1G;CACNA1S;TRPA1;CACNB3;TRPV1;CACNA1A;CACNA1I;TRPV4;CACNA1F;CACNB1;TRPM8;CACNA1H;OPRM1;TRPV3;CACNB2;CACNB4;TRPV2;CACNA1D;CACNA1C;CHRNA7 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C8;CYP3A5 GO:0034765| regulation of ion transmembrane transport CACNA1D;CACNB4;CACNA1C;CACNB2;CACNA1H;CACNB1;CACNA1A;CACNA1I;CACNA1F;CACNB3;CACNA1G;CACNA1S GO:0007601| visual perception CACNB2;CYP1B1;GLRB;CACNA1F;CRYZ;GLRA1 GO:0050796| regulation of insulin secretion CACNA1A;CNR1;CACNA1C;CACNA1D GO:0007204| elevation of cytosolic calcium ion concentration CACNA1A;TRPV4;TRPV1;HTR2A;OPRM1;CACNA1C GO:0007520| myoblast fusion CACNA1H GO:0086010| CACNA1G;CACNA1S;CACNA1F;CACNA1A;CACNA1I;CACNA1H GO:0043603| cellular amide metabolic process CYP2C9 GO:0006816| calcium ion transport CACNB3;TRPA1;CACNA1S;CACNA1G;TRPM8;CACNB1;CACNA1F;CACNA1I;TRPV4;CACNA1A;TRPV1;CACNB2;TRPV3;CACNA1H;CHRNA7;CACNA1C;CACNA1D;TRPV2;CACNB4 GO:0034651| cortisol biosynthetic process CACNA1H GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0007268| synaptic transmission HTR2A;GLRA3;CACNB2;OPRD1;OPRM1;CACNB4;CACNB3;GLRA1;CACNA1G;CACNB1;VDAC1;GLRB GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1 GO:0002027| regulation of heart rate CACNA1G GO:0007507| heart development PPARG;CACNA1C GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CACNA1D GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1G;CACNA1I GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0035725| sodium ion transmembrane transport CACNA1H;CACNA1G;CACNA1I GO:0098662| CACNA1H GO:0008016| regulation of heart contraction CACNA1H GO:0086091| CACNB2;CACNA1C;CACNA1D;CACNA1G GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 18632:[DB14011 DB03061] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03061|(R)-N-(1-Methyl-Hexyl)-Formamide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ADH1C;PTGS1;ALOX5;GPX1;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 18633:[DB14011 DB03802] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TRPV1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;ESR1;OPRM1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;ESR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0006351| transcription, DNA-dependent PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG 18634:[DB14011 DB04365] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;CHRM1;HTR1A;HTR2A;PTGS2;HMGCR GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRM1;CHRM3;GPR18;PPARG GO:0007399| nervous system development CHRM1;GLRB;CHRM3;SMPD1 GO:0008283| cell proliferation CHRM3;CYP1A1;GPX1;HTR1A;CHRM1 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0050890| cognition CHRNA7;CHRM1 GO:0006939| smooth muscle contraction CHRM3;HTR2A GO:0007165| signal transduction CHRNA7;CHRM1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;CHRM3;SMPD1 18635:[DB14011 DB01593] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes GLRA1;SOD1 common pathways GO:0019233| sensory perception of pain TRPA1;BDKRB1;TRPV1;CNR1;HTR2A;OPRD1;OPRM1;PTGS2;CNR2 GO:0045773| positive regulation of axon extension FN1;TRPV2 GO:0045541| negative regulation of cholesterol biosynthetic process SOD1;APOE GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0006351| transcription, DNA-dependent PARP1;ESR1;HDAC8;TP53;HDAC4;PPARG;EEF1A1;HDAC1;TP73;ENO1 GO:0051592| response to calcium ion AANAT;PDCD6;FGA GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0001525| angiogenesis FN1;S100A7;CYP1B1;PDCD6;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1;AGT;C5 GO:0045821| positive regulation of glycolysis GAPDHS;INS;HTR2A GO:0045471| response to ethanol GSN;OPRM1;S100A8;HMGCR;MGMT;SOD1;CNR1;CAT;TP53;TUFM GO:0045776| negative regulation of blood pressure BDKRB1;CNR1 GO:0000060| protein import into nucleus, translocation OPRD1;MT3 GO:0071294| cellular response to zinc ion PARP1;MT1A;MT2A;GLRA1 GO:0000303| response to superoxide SOD1 GO:0086091| JUP;DSP;CACNA1G GO:0008090| retrograde axon cargo transport SOD1 GO:0061045| negative regulation of wound healing APCS;HMGCR GO:0010575| positive regulation vascular endothelial growth factor production C3;C5;PTGS2;CYP1B1 GO:0001774| microglial cell activation TRPV1;APP;CLU GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;APOE GO:0097305| GLRA1 GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0071260| cellular response to mechanical stimulus HDAC4;PTGS2;AGT GO:0006629| lipid metabolic process CYP1A2;PTGS2;APOL1;HMGCR;NAPEPLD;CYP3A4;C3;PON1;GPX1;NAAA;PTGS1;CLU;APOE;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;APOA1;DAGLA;CYP2D6;APOBR GO:0051974| negative regulation of telomerase activity TP53;PPARG GO:0071361| cellular response to ethanol GLRA1 GO:0007399| nervous system development GLRB;SMPD1;APP;APLP1;HDAC4;IL3;NME1 GO:0002027| regulation of heart rate CACNA1G;MDM2;AGT GO:0001503| ossification ALOX15;AHSG;MMP9 GO:0007507| heart development PPARG;MDM2 GO:1990090| TRPV1;APP GO:0008152| metabolic process CPE;TPI1;ACAT1;IDE;SMPD1;ASPA GO:0042310| vasoconstriction AGT;HTR1A GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;HBA1;HBB;TRPA1 GO:0042307| positive regulation of protein import into nucleus PTGS2;JUP GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0050727| regulation of inflammatory response S100A8;PTGS2;S100A9;ESR1;PGLYRP2;AHSG GO:0071312| cellular response to alkaloid MDM2;TRPV1 GO:0043065| positive regulation of apoptotic process SMPD1;TP53;APP;CLU;MMP9;PPARG;KNG1;CYP1B1;TRPV1;TP73;IDO1;PTGS2;SOD1;CNR1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0001934| positive regulation of protein phosphorylation F2;APP;MMP9;MT3;CHRNA7;C3 GO:0043534| blood vessel endothelial cell migration APOA1;GPX1 GO:1902004| CLU;APOE;APP;CHRNA7 GO:0007565| female pregnancy AGT;IDO1;PZP GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MT3;GPX1;PTGS2;MDM2 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels PON1;SOD1;PSPH GO:0071603| endothelial cell-cell adhesion JUP;CYP1B1 GO:0043524| negative regulation of neuron apoptosis APOE;HDAC1;TP73;SOD1;MT3 GO:0071320| cellular response to cAMP AANAT;APP GO:0010629| negative regulation of gene expression AGT;NME1;HDAC8;OPRD1;ESR1;APP;MDM2;HDAC1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GLRB;VDAC1;GLRA1;CACNA1G;APP GO:0008542| visual learning HMGCR;APP GO:0006879| cellular iron ion homeostasis ABCG2;CP;SOD1;TF GO:0007595| lactation NME1;SLC29A1 GO:0019430| removal of superoxide radicals PRDX1;APOA4;MT3;SOD1 GO:0051924| regulation of calcium ion transport AGT;OPRD1 GO:1902476| APOL1;GLRA3;GLRA1;GLRB GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;VTN;INS;IL3;AGT;APP;TP53 GO:0043087| regulation of GTPase activity SOD1 GO:0060013| righting reflex GLRB;GLRA1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JUP;ESR1;HDAC4;PPARG;APP GO:0019226| transmission of nerve impulse SOD1 GO:0016032| viral reproduction HDAC1;IDE;MDM2;TP53;APOA2;CFH;VDAC1;TP73;HTR2A;SIVA1 GO:0001964| startle response GLRA1;GLRB GO:0006955| immune response IGKV1-17;JCHAIN;C1R;C8B;IL3;CNR2;VTN;IGLV3-21;OPRD1;C8A;IGHA1;C3;C1QC GO:0010942| positive regulation of cell death PTGS2;MT3;HBA1;HBB GO:0006954| inflammatory response SERPINA3;TRPV1;KNG1;ALOX15;IDO1;BDKRB1;HDAC4;KRT16;C4B;PTGS1;ALOX5;PTGS2;CNR2;S100A8;S100A9;C5;KLKB1;C3 GO:1902430| CLU;APOE;CHRNA7 GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A8;S100A9;AGT;INS;CAT;CLU;APP;PLA2G1B GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1 GO:0051289| protein homotetramerization CAT;TRPA1;IDE;CRYZ;ALDOA;TP53;TRPM8;TRPV1 GO:0010976| positive regulation of neuron projection development APOE;CNR1;AGT;NME1 GO:0007601| visual perception GLRB;CYP1B1;GLRA1;CRYZ GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;APP GO:0002262| myeloid cell homeostasis SOD1 GO:0007204| elevation of cytosolic calcium ion concentration AGT;HTR2A;ESR1;OPRM1;KNG1;TRPV1;TRPV4;APP;BDKRB1 GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PARP1 GO:0007613| memory APP;PTGS2;HTR2A;CNR1;CHRNA7 GO:0045454| cell redox homeostasis PRDX1;GSR;PDIA3;GPX1;P4HB GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0060012| synaptic transmission, glycinergic GLRA3;GLRA1;GLRB GO:0001975| response to amphetamine HDAC1;SOD1;CNR2 GO:0007566| embryo implantation SOD1;PTGS2;MMP9 GO:0040014| regulation of multicellular organism growth APP;SOD1 GO:0090201| negative regulation of release of cytochrome c from mitochondria CLU;GPX1 GO:0019216| regulation of lipid metabolic process AGT;CNR1;HMGCR;APOA1;SERPINA3;PPARG;CYP1A1;APOA2 GO:0050729| positive regulation of inflammatory response TRPV4;S100A8;S100A9;AGT GO:0046718| entry of virus into host cell IDE;HTR2A;SIVA1 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0050890| cognition CHRNA7;INS GO:0051384| response to glucocorticoid stimulus PTGS2;CPN1;APOA2 GO:0070542| response to fatty acid PON1;PTGS2;CAT GO:0010332| response to gamma radiation TP73;TP53;GPX1;PARP1 GO:0065009| regulation of molecular function AGT;IL3;TRPV1 GO:0034644| cellular response to UV PTGS2;TP73;TP53 GO:0006641| triglyceride metabolic process GPX1;CAT;APOA2;APOE;APOBR GO:0034116| positive regulation of heterotypic cell-cell adhesion FGA;ALOX15 GO:2000344| positive regulation of acrosome reaction GLRA1;CACNA1H GO:0090336| positive regulation of brown fat cell differentiation PTGS2;INS GO:0007420| brain development MT3;ACAT1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PDIA3;BDKRB1;IGFALS;FGA;PLA2G1B;CACNA1I;C3;HTR2A;GPR12;CNR1;HTR1A;GPR55;ESR1;OPRD1;OPRM1;CNR2;CHRNA7;JUP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;OPRD1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;FGA GO:0006821| chloride transport GLRA1;GLRB;GLRA3 GO:1900273| CHRNA7;INS;APP GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;TP53 GO:0001819| positive regulation of cytokine production AGT;SOD1 GO:0010811| positive regulation of cell-substrate adhesion ALOX15;VTN GO:0060047| heart contraction GPX1;SOD1 GO:0042633| hair cycle PTGS2;KRT14;KRT16 GO:0045777| positive regulation of blood pressure CNR1;AGT GO:0008344| adult locomotory behavior OPRD1;APP GO:0001895| retina homeostasis JCHAIN;PRDX1;SOD1;IGHA1;TF;KRT1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0040029| regulation of gene expression, epigenetic HDAC4;GPX1 GO:0046470| phosphatidylcholine metabolic process PON1;PLA2G1B;APOA4 GO:0015949| nucleobase-containing small molecule interconversion NME1;GSR GO:0044240| multicellular organismal lipid catabolic process APOA4;PLA2G1B GO:0014070| response to organic cyclic compound ACAT1;AANAT;MGMT;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1;TP53 GO:0002227| innate immune response in mucosa APOA4;PLA2G1B GO:0009636| response to toxin GPX1;CAT;PON1;MGMT;CYP1B1;MDM2;CYP1A1 GO:0009395| phospholipid catabolic process APOA2;NAPEPLD GO:0009411| response to UV CAT;TP53 GO:0046620| regulation of organ growth SOD1 GO:0006919| activation of caspase activity PPARG;PDCD6;S100A8;S100A9 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;SIVA1;CAT GO:0008283| cell proliferation PRDX1;CYP1A1;KRT16;TP53;MT3;GPX1;HTR1A GO:0046340| diacylglycerol catabolic process DAGLA;APOA2 GO:2000378| negative regulation of reactive oxygen species metabolic process MT3;VDAC1 GO:0006811| ion transport GLRA3;CACNA1H;TF;TRPV3;CHRNA7;CP;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1 GO:0035865| cellular response to potassium ion SOD1;CACNA1H GO:0008217| regulation of blood pressure PPARG;HBB;PTGS2;SOD1;PTGS1;AGT GO:0008285| negative regulation of cell proliferation TP73;CYP1B1;APP;TP53;HDAC4;PPARG;HDAC1;NME1;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration APOE;PPARG GO:0061844| APP;S100A7;SEMG1;KNG1;F2;PLA2G1B;S100A9;KRT6A;DCD GO:0032930| positive regulation of superoxide anion generation APP;AGT;SOD1 GO:1902042| FGA;GPX1 GO:0007584| response to nutrient PPARG;APOA1;CNR1;HMGCR GO:0070301| cellular response to hydrogen peroxide CYP1B1;MDM2 GO:0043627| response to estrogen stimulus APOA1;PPARG;APOA2;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;FN1;AGT;ESR1 GO:0045740| positive regulation of DNA replication PLA2G1B;INS;IL3 GO:0001523| retinoid metabolic process APOA1;APOA2;APOA4;APOE;TTR;NAPEPLD GO:0055088| lipid homeostasis PPARG;APOA4;APOE GO:0010043| response to zinc ion KRT14;S100A8;AANAT GO:0051291| protein heterooligomerization JUP;SEMG1;GLRA1;IDE;HBB;HBA1;GLRB GO:0001890| placenta development SOD1;PPARG GO:0006749| glutathione metabolic process GSR;SOD1;GPX1 GO:0034976| response to endoplasmic reticulum stress P4HB;ALOX15;PDIA3 GO:0030336| negative regulation of cell migration CYP1B1;KRT16 GO:0071276| cellular response to cadmium ion MT3;CYP1A2;GSN;SOD1;MT1A;MMP9 GO:0071333| cellular response to glucose stimulus SLC29A1;NME1 GO:0030317| sperm motility GAPDHS;CACNA1I GO:0001660| fever generation IL3;TRPV1 GO:1905906| APOE;APP;CHRNA7 GO:0014824| artery smooth muscle contraction AGT;HTR2A GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:0043542| endothelial cell migration CYP1B1;S100A2 GO:0006695| cholesterol biosynthetic process APOA1;APOA4;HMGCR GO:0034599| cellular response to oxidative stress CCS;GPX1;MT3;CAT;PARP1;P4HB;SOD1;MGMT;PRDX1;GSR;HDAC1 GO:0071230| cellular response to amino acid stimulus GLRA1 GO:0033344| cholesterol efflux APOA4;APOE;APOA2;ABCG2;APOA1 GO:0032526| response to retinoic acid TP53;PPARG GO:0097332| SOD1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGT;HTR2A;ESR1;OPRD1;OPRM1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0007611| learning or memory CHRNA7;CNR1;APP GO:0030308| negative regulation of cell growth MT3;AGT;PPARG;BDKRB1;TP53;ENO1 GO:0000302| response to reactive oxygen species S100A7;APOE;PRDX1;SOD1;CAT;GPX1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;S100A8;CYP1A2;CNR2;PTGS2;IDO1;CYP1A1;HDAC1;S100A7;BDKRB1 GO:0001508| regulation of action potential GLRA1;CACNA1G GO:0008203| cholesterol metabolic process CAT;APOL1;HMGCR;PON1;APOBR;APOA1;APOE;APOA4;APOA2;APP GO:0007612| learning VDAC1;APP;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;JUP;AGT;PTGS1 GO:0042060| wound healing DSP;ALOX15;TP53;FN1;INS;KRT6A;OPRM1;GSN;S100A8 GO:0043312| neutrophil degranulation GSN;S100A8;S100A9;C3;ALOX5;HRNR;JUP;CAT;TTR;SERPINA1;KRT1;ORM2;ALDOA;S100A7;HBB;MMP9;EEF1A1;A1BG;SERPINA3;DSP;AHSG GO:0010288| response to lead ion CAT;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;TP53;MDM2;HDAC4;PPARG;HDAC1;ENO1;TRPV4;TP73;TRPV1;PARP1;ESR1;HDAC8 GO:0007155| cell adhesion IGFALS;CYP1B1;APLP1;FN1;APP;JUP;VTN GO:0045087| innate immune response JCHAIN;CFB;CFH;FCN3;FGA;KRT16;PPARG;S100A7;IGHM;CLU;APP;C1R;C8B;C1QB;PGLYRP2;C4BPA;C8G;C4B;C5;C1S;IGHA1;CFI;C3;C1QC;S100A8;APOL1;F12;APCS;C4BPB;S100A9;C8A GO:0034097| response to cytokine stimulus AANAT;ITIH4;PTGS2;TP53 GO:0007628| adult walking behavior GLRB;GLRA1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;PSPH;BDKRB1 GO:0035722| interleukin-12-mediated signaling pathway CA1;P4HB;SOD1 GO:0043066| negative regulation of apoptotic process CAT;MT3;GPX1;MGMT;SOD1;PTGS2;HMGCR;HDAC1;MMP9;TP53;MDM2 GO:0001822| kidney development TP73;AGT;CAT GO:0042311| vasodilation AGT;GPX1;KNG1;APOE GO:0032259| methylation CYP1A2;MGMT GO:1902177| SOD1 GO:0009615| response to virus CYP1A1;CLU;ENO1 GO:0007340| acrosome reaction GLRB;GLRA1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;KRT6A;HMGCR;PTGS2;CHRNA7;INS;AGT;IL3;HDAC1;FN1;HDAC4;MDM2;F2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;HDAC4;PPARG;APP;TP53;TP73;PLA2G1B;ESR1;PARP1 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;OPRM1;OPRD1;CPE;GLRA3 GO:0007626| locomotory behavior SOD1;OPRM1;APP GO:0046677| response to antibiotic TP53;MDM2;CYP1A1;SOD1 GO:0002576| platelet degranulation APP;ORM2;CLU;ALDOA;SERPINA4;FN1;KNG1;FGA;A1BG;SERPINA3;APOA1;AHSG;ITIH3;TF;SOD1;APLP2;ITIH4;SERPINA1;A2M GO:0055114| oxidation-reduction process PRDX1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PDIA3;CYP1A1;CYP2C9;GAPDHS;CRYZ;CP;ALOX5;PTGS1;GPX1;CCS;CAT;ADH1C;PTGS2;CYP3A7;CYP1A2;P4HB;HMGCR;CYP3A4;SOD1 GO:0007569| cell aging TP53;SOD1 GO:0050884| neuromuscular process controlling posture GLRA1 GO:0050808| synapse organization APP;CHRNA7 GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0019731| antibacterial humoral response PLA2G1B;JCHAIN;APP;SEMG1;IGHM;IGHA1 GO:0051702| interaction with symbiont FN1;GPX1 GO:1902176| INS;GPX1 GO:0007517| muscle organ development UTRN;CACNA1H GO:0045893| positive regulation of transcription, DNA-dependent TP73;HDAC1;HDAC4;PPARG;TP53;MT3;AGT;ESR1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;C3;ALOX15 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0071407| cellular response to organic cyclic compound MGMT;CYP1A1;MDM2;CYP1B1 GO:0030593| neutrophil chemotaxis PLA2G1B;S100A8;S100A9 GO:0006355| regulation of transcription, DNA-dependent ENO1;TP73;TP53;HDAC1;EEF1A1;PPARG;HDAC4;HDAC8;INS;PARP1;ESR1 GO:0010666| positive regulation of cardiac muscle cell apoptosis AGT;HMGCR GO:0042493| response to drug NME1;CAT;SOD1;HTR2A;MGMT;CYP1A2;PTGS2;APOA1;ABCG2;TP73;HDAC1;TRPA1;CYP1A1;PPARG;HDAC4;TP53;SMPD1;MDM2;ABCC1;APOA2 GO:0050830| defense response to Gram-positive bacterium PGLYRP2;KRT6A;DCD;PLA2G1B;APP GO:0018158| protein oxidation APOA2;APOA1;GPX1 GO:0050905| neuromuscular process GLRB;GLRA1 GO:0051897| positive regulation of protein kinase B signaling cascade APP;INS;GPX1 GO:0060326| cell chemotaxis ABCC1;C5 GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0043278| response to morphine OPRM1;CNR1;MDM2 GO:0016525| negative regulation of angiogenesis AGT;PPARG GO:0007015| actin filament organization PLA2G1B;TRPV4;ALDOA GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;PON1;ALOX5;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation HDAC4;HMGCR;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TP53;TP73;TRPV1 GO:0050728| negative regulation of inflammatory response APOA1;APOE;KRT1;CNR2 GO:0034465| response to carbon monoxide SOD1 GO:0055093| response to hyperoxia CAT;HDAC1;CYP1A1;TP53 GO:0006801| superoxide metabolic process CCS;SOD1 GO:0035025| positive regulation of Rho protein signal transduction GPR55;APOA1;GPR18 GO:0006810| transport TTR;TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade AGT;INS;CAT;F2 GO:0007568| aging AGT;CAT;PTGS2;GSN;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;TP53;KRT16;CYP1A1;KRT14 GO:0015909| long-chain fatty acid transport PPARG;APOE GO:0071456| cellular response to hypoxia MT3;SLC29A1;P4HB;PTGS2;OPRD1;MDM2;TP53 GO:0097756| INS;HMGCR;PTGS2 GO:0030595| leukocyte chemotaxis S100A9;CNR2 GO:0010468| regulation of gene expression CYP1A2;TP73;F2;APOE;MDM2;APP GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;APOL1;CYP3A4;APOE;CYP2C9;CYP1A1;CYP1B1;CYP2C19;APOA1;APOBR;CYP2D6;CYP17A1;CYP3A5 GO:0034605| cellular response to heat TP53;TRPV1;TRPV4;PDCD6;PTGS2 GO:0042554| superoxide anion generation SOD1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;MDM2;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;C5;HTR1A;APLP2;C3;HTR2A;GPR12;CNR1;AGT;INS;APOE;BDKRB1;APP;PPARG;GPR18;F2;KNG1;APOA1 GO:0098815| APP;CHRNA7 GO:0032355| response to estradiol stimulus AGT;CAT;CYP1A2;PTGS2;ESR1 GO:0009611| response to wounding F2;FN1;CYP1A1;GPX1 GO:0043085| positive regulation of catalytic activity AGT;MT3;SOD1;APOA2 GO:0006820| anion transport VDAC1;GLRA1 GO:0007605| sensory perception of sound GPX1;SOD1 GO:0042391| regulation of membrane potential GLRB;CACNA1G;GLRA1;CACNA1H GO:0006979| response to oxidative stress CAT;KRT1;MT3;GPX1;PTGS1;SOD1;PTGS2;PRDX1;APOE;TP53;APP GO:1901214| CHRNA7;APOE;CLU GO:0043388| positive regulation of DNA binding MMP9;PPARG;NME1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;AGT;INS;CLU;APP;HBB;TRPV1 GO:0006936| muscle contraction CACNA1H;GLRA1;UTRN GO:0098869| GSR;HBA1;HBB;APOE;CAT;PTGS1;GPX1;S100A9;PTGS2 GO:0006874| cellular calcium ion homeostasis APOE;TRPV4;TRPM8;HTR2A;GPR12;CHRNA7 GO:0048538| thymus development SOD1 GO:0051260| protein homooligomerization ACAT1;GLRA3;APP;GLRA1;IDE GO:0002376| immune system process IGHM;CLU;C8B;C1QB;C1R;IGKV1-17;CFB;IDO1;FCN3;CFH;FGA;IGHA1;C5;C1S;C1QC;CFI;C3;IGLV3-21;S100A8;S100A9;C8A;C4BPB;C4BPA;PGLYRP2;C4B;C8G GO:0031100| organ regeneration APOA1;APOA2;PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;INS;CNR1 GO:0001541| ovarian follicle development SOD1 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;PRDX1;HBB;HBA1;APOA4 GO:0045766| positive regulation of angiogenesis CHRNA7;C5;C3;CYP1B1;PDCD6 GO:0031532| actin cytoskeleton reorganization TRPV4;S100A9 GO:0006915| apoptotic process S100A9;PARP1;S100A8;GSN;GPX1;MT3;SIVA1;APP;TP53;CLU;APLP1;PDCD6;TP73;VDAC1 GO:0050714| positive regulation of protein secretion PLA2G1B;FGA GO:0030855| epithelial cell differentiation PPARG;KRT14;VDAC1 GO:0042220| response to cocaine SMPD1;MDM2;CNR1;OPRM1 GO:0000187| activation of MAPK activity C5;SOD1;CHRNA7;APP;TP73;PLA2G1B GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;APOA1;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;FGA;ALOX15;APP;S100A7;CHRNA7;MT3;OPRM1;HMGCR;GPR55;HTR2A GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0051591| response to cAMP NME1;AANAT GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0043200| response to amino acid stimulus GLRA3;TP53;GLRB GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0015758| glucose transport PLA2G1B;INS GO:0031000| response to caffeine PPARG;HDAC1;TP53 GO:0051262| protein tetramerization HMGCR;CAT;APP;TP53;TP73 GO:0045892| negative regulation of transcription, DNA-dependent MT3;HDAC1;HDAC4;PPARG;MDM2;TP53;ENO1 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0006644| phospholipid metabolic process APOA1;PLA2G1B;NAPEPLD GO:0071356| cellular response to tumor necrosis factor HDAC1;HDAC4;TRPV1 GO:0048511| rhythmic process AANAT;TP53;HDAC1;PPARG GO:0043407| negative regulation of MAP kinase activity APOE;SMPD1;HMGCR GO:0046716| muscle cell homeostasis ALDOA;SOD1 GO:0048714| positive regulation of oligodendrocyte differentiation TP73;ASPA;PPARG;HDAC1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0007283| spermatogenesis SOD1;CNR1 GO:0001666| response to hypoxia CYP1A1;CHRNA7;MT3;CAT GO:0002674| negative regulation of acute inflammatory response PPARG;INS;APCS GO:0007202| activation of phospholipase C activity GPR55;HTR2A;AGT GO:0010628| positive regulation of gene expression INS;MT3;GSN;TRPV4;CLU;APP;TP53;MDM2;FN1 GO:0046688| response to copper ion AANAT;SOD1 GO:0010977| negative regulation of neuron projection development TRPV4;MDM2;APOE GO:0032460| negative regulation of protein oligomerization OPRD1;INS 18636:[DB14011 DB00075] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;CD3D GO:0070207| protein homotrimerization TRPM8;CD247 GO:0043312| neutrophil degranulation FCGR3B;FCGR2A;ALOX5;CAT GO:0045087| innate immune response C1QC;C1S;C1QA;PPARG;C1QB;C1R;FCGR1A GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0051260| protein homooligomerization CD3G;GLRA3;ACAT1;CD3D;GLRA1;CD3E GO:0002376| immune system process C1S;C1QC;CD3G;C1QA;CD3D;C1R;C1QB;CD3E;IDO1;FCGR2A;FCGR1A;CD247 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CD3E;GPR18;PPARG GO:0010628| positive regulation of gene expression TRPV4;CD3E GO:0007166| cell surface receptor linked signaling pathway CD3G;CD3D;TRPA1;CD3E;TRPV1;CD247 GO:0016032| viral reproduction CD247;VDAC1;FCGR2B;HTR2A GO:0006955| immune response C1R;FCGR2B;FCGR3B;FCGR1A;CNR2;OPRD1;FCGR2C;FCGR3A;C1QC GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;FCGR2B;TRPV1;IDO1;ALOX15 GO:0030217| T cell differentiation GPR18;CD3D GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPM8;TRPV1;CD247;CAT GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD3E GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 GO:0010629| negative regulation of gene expression OPRD1;CD3E GO:0007165| signal transduction PLA2G1B;CACNA1I;FCGR1A;SMPD1;GPR18;PPARG;FCGR2B;CHRNA7;FCGR2C;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;CD3E 18637:[DB14011 DB13893] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways GO:0050482| arachidonic acid secretion PLA2G10;PLA2G1B GO:0032869| cellular response to insulin stimulus PLA2G1B;ENPP1;PPARG GO:0036150| PLA2G10;PLA2G1B GO:0036148| PLA2G1B;PLA2G10 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;PLA2G10;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0008152| metabolic process ACAT1;SMPD1;ENPP1 GO:0036149| PLA2G10;PLA2G1B GO:0006955| immune response OPRD1;CNR2;ENPP1 GO:0036152| PLA2G1B;PLA2G10 GO:0006644| phospholipid metabolic process PLA2G10;NAPEPLD;PLA2G1B GO:0016042| lipid catabolic process DAGLA;PLA2G1B;NAPEPLD;PLA2G10 GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G10 GO:0030308| negative regulation of cell growth PPARG;ENPP1 GO:0036151| PLA2G10;PLA2G1B GO:0019369| arachidonic acid metabolic process CYP1B1;CYP2D6;DAGLA;ALOX15;FAAH;PLA2G10 18638:[DB14011 DB04194] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04194|Chitotriose LYZ common genes common pathways GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B GO:0043312| neutrophil degranulation LYZ;CAT;ALOX5 GO:0006954| inflammatory response TRPV1;LYZ;ALOX15;IDO1;ALOX5;PTGS1;CNR2;PTGS2 GO:0008152| metabolic process SMPD1;LYZ;ACAT1 GO:0001895| retina homeostasis SOD1;LYZ 18639:[DB14011 DB02057] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02057|(S)-AMPA GRIA2 common genes common pathways GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;GRIA2;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1 GO:0007165| signal transduction CHRNA7;GRIA2;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GRIA2;GLRA1;CACNA1G;GLRB;VDAC1 GO:0034220| ion transmembrane transport TRPV1;GLRB;GLRA1;TRPA1;GRIA2;CHRNA7;GLRA3 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;GRIA2;SLC29A1;GLRA1;GLRB;TRPV1 18640:[DB14011 DB08387] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PDE10A GO:0007165| signal transduction PDE10A;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0008152| metabolic process ACAT1;PDE10A;SMPD1 18641:[DB14011 DB05932] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0007399| nervous system development GLRB;SMPD1;VEGFA GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;VEGFA GO:0010575| positive regulation vascular endothelial growth factor production FLT4;CYP1B1;PTGS2 GO:0048469| cell maturation VEGFA;PPARG GO:0001525| angiogenesis CYP1B1;FLT4;VEGFA;FLT1;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A GO:0007595| lactation VEGFA;SLC29A1 GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;VEGFA;FLT4 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA;OPRD1 GO:0043117| positive regulation of vascular permeability VEGFA;TRPV4 GO:0051781| positive regulation of cell division VEGFA;CAT GO:0002576| platelet degranulation VEGFA;SOD1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;FLT1;VEGFA;HMGCR;CHRNA7;FLT4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;PLA2G1B GO:0001822| kidney development CAT;VEGFA GO:0043066| negative regulation of apoptotic process FLT4;HMGCR;VEGFA;PTGS2;SOD1;GPX1;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;TRPV4;TRPV1 GO:0030324| lung development CYP1A2;VEGFA GO:0046330| positive regulation of JNK cascade FLT4;TRPV4 GO:0030224| monocyte differentiation PPARG;VEGFA GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0071456| cellular response to hypoxia VEGFA;PTGS2;OPRD1;SLC29A1 GO:0048514| blood vessel morphogenesis CYP1B1;FLT4;FLT1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FLT1;CAT GO:0010628| positive regulation of gene expression VEGFA;TRPV4 GO:0001666| response to hypoxia VEGFA;CAT;CHRNA7;CYP1A1 GO:0043406| positive regulation of MAP kinase activity FLT1;VEGFA;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;FLT4;CHRNA7;GPR55;HTR2A;OPRM1;VEGFA;HMGCR GO:0030855| epithelial cell differentiation VEGFA;PPARG;VDAC1 GO:0045766| positive regulation of angiogenesis FLT1;VEGFA;CHRNA7;CYP1B1 GO:0001541| ovarian follicle development SOD1;VEGFA 18642:[DB14011 DB06786] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06786|Halcinonide SMO;CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT GO:0045893| positive regulation of transcription, DNA-dependent SMO;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;SMO GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;SMO;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;SMO GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;SMO;HTR2A GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent SMO;PPARG GO:0048741| skeletal muscle fiber development SMO;GPX1 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0010628| positive regulation of gene expression TRPV4;SMO GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0010468| regulation of gene expression SMO;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;SMO;HTR2A;CNR1;GPR12 GO:0048565| digestive tract development SMO;CYP1A1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression OPRD1;SMO GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0001503| ossification SMO;ALOX15 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0042307| positive regulation of protein import into nucleus PTGS2;SMO GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;SMO GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;SMO;CNR1;GPR12;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0001649| osteoblast differentiation SMO;CAT 18643:[DB14011 DB07513] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07513|7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0009636| response to toxin CYP1B1;MAOB;CYP1A1;GPX1;CAT GO:0010269| response to selenium ion GPX1;MAOB GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;MAOB;CRYZ;CYP2C9;CYP1A1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;MAOB;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0022900| electron transport chain CYP1A2;MAOB;GSR;IDO1 GO:0032496| response to lipopolysaccharide IDO1;MAOB;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;MAOB;SOD1;CYP1A2 18644:[DB14011 DB13141] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A7;CYP3A5;CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0036378| CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP2C9;CYP1A1;CRYZ;GPX1;ALOX5;PTGS1;CYP3A43;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 18645:[DB14011 DB05096] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05096|LY2140023 GRM2;GRM3 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;GRM3;SMPD1;GRM2;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0051966| regulation of synaptic transmission, glutamatergic GRM3;GRM2;CNR1 GO:0007194| negative regulation of adenylate cyclase activity GRM2;GRM3;OPRM1 GO:0007268| synaptic transmission CACNA1G;GLRA1;GRM3;GLRB;VDAC1;GRM2;OPRD1;OPRM1;GLRA3;HTR2A GO:0014047| glutamate secretion TRPV1;GRM2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;GRM2;GRM3;GPR18;PPARG GO:0007216| metabotropic glutamate receptor signaling pathway GRM2;DAGLA;GRM3 18646:[DB14011 DB05343] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05343|Arundic acid S100B common genes common pathways GO:0071456| cellular response to hypoxia SLC29A1;S100B;PTGS2;OPRD1 GO:0007611| learning or memory CHRNA7;S100B;CNR1 GO:0045087| innate immune response S100B;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;S100B;HTR2A;HTR1A;HMGCR;PTGS2 GO:0008283| cell proliferation S100B;GPX1;HTR1A;CYP1A1 GO:0007613| memory PTGS2;CNR1;HTR2A;S100B;CHRNA7 GO:0051384| response to glucocorticoid stimulus S100B;PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;S100B;PTGS2;SOD1;CNR1 18647:[DB14011 DB00134] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0051289| protein homotetramerization CAT;TRPM8;TRPV1;CRYZ;TRPA1;MAT1A GO:0048678| response to axon injury SOD1;MTR GO:0008152| metabolic process SMPD1;ACAT1;MTHFR GO:0007399| nervous system development MTR;SMPD1;GLRB GO:0008283| cell proliferation GPX1;GLUL;HTR1A;CYP1A1 GO:0051291| protein heterooligomerization GLRA1;MAT2A;GLRB GO:0032869| cellular response to insulin stimulus MARS;PLA2G1B;PPARG GO:0042493| response to drug PTGS2;CYP1A2;MTHFR;SOD1;HTR2A;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent MSRB2;PPARG GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;MSRB1;CYP1B1;CRYZ;CYP2C9;CYP1A1;MSRB2;MSRA;CAT;MTRR;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;MTHFR;CYP1A2;CYP3A7;PTGS2 GO:0032259| methylation MAT2A;BHMT;MAT1A;MTR;BHMT2;MTRR;CYP1A2;MAT2B GO:0045087| innate immune response MSRB1;PPARG GO:0043200| response to amino acid stimulus MTHFR;GLRA3;GLRB GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLC16A10;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;TRPA1;CACNA1G;ABCC1 GO:0001666| response to hypoxia MTHFR;CAT;CHRNA7;CYP1A1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;GLUL GO:0009235| cobalamin metabolic process MTR;MTRR;ABCC1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;MSRA;PTGS2;SOD1;MSRB1;MSRB2 GO:0051260| protein homooligomerization ACAT1;GLUL;GLRA3;GLRA1 GO:0002376| immune system process MSRB1;IDO1 18648:[DB14011 DB04973] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04973|LErafAON RAF1 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;RAF1;CAT;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;PLA2G1B;PPARG GO:0042060| wound healing RAF1;OPRM1;ALOX15 GO:0001666| response to hypoxia CYP1A1;RAF1;CAT;CHRNA7 GO:0006915| apoptotic process RAF1;GPX1;VDAC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;RAF1;HMGCR;GPR55;HTR2A GO:0034220| ion transmembrane transport RAF1;GLRA3;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0048538| thymus development SOD1;RAF1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;RAF1;PTGS2 GO:0001934| positive regulation of protein phosphorylation RAF1;CHRNA7 GO:0007507| heart development PPARG;RAF1 GO:0035556| intracellular signal transduction PLA2G1B;RAF1 GO:0008285| negative regulation of cell proliferation RAF1;PTGS2;OPRM1;PPARG;CYP1B1 GO:1902042| GPX1;RAF1 GO:0008283| cell proliferation GPX1;RAF1;HTR1A;CYP1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;RAF1;PTGS2 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;RAF1;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 18649:[DB14011 DB05895] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05895|HGS-TR2J TNFRSF10B common genes common pathways GO:1902042| GPX1;TNFRSF10B GO:0034976| response to endoplasmic reticulum stress TNFRSF10B;ALOX15 GO:0006919| activation of caspase activity PPARG;TNFRSF10B GO:0007165| signal transduction TNFRSF10B;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0006955| immune response TNFRSF10B;OPRD1;CNR2 GO:0006954| inflammatory response PTGS1;ALOX5;TNFRSF10B;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;TNFRSF10B GO:0071260| cellular response to mechanical stimulus TNFRSF10B;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TNFRSF10B;TRPA1;TRPV1 GO:0006915| apoptotic process VDAC1;TNFRSF10B;GPX1 GO:0042127| regulation of cell proliferation PTGS2;TNFRSF10B;PTGS1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;TNFRSF10B;OPRM1;CYP1A2;CNR2;PTGS2 18650:[DB14011 DB02943] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways GO:0006749| glutathione metabolic process GSR;GSTA1;SOD1;GPX1 GO:0008152| metabolic process GSTA1;SMPD1;ACAT1 GO:0030855| epithelial cell differentiation PPARG;GSTA1;VDAC1 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSTA1;GSR 18651:[DB14011 DB01327] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0007155| cell adhesion IL2;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation IL2;IL15;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0002576| platelet degranulation ABCC4;SOD1;ALB GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;IL2;ALB GO:0032259| methylation TPMT;CYP1A2 GO:0008203| cholesterol metabolic process HMGCR;PON1;CAT GO:0050728| negative regulation of inflammatory response IL2;CNR2 GO:0010243| response to organic nitrogen TRPV1;PTGS2;ABCC4 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;HMGCR;PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;PON1;GPX1;ALOX5 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;ABCC4;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCC4;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0099133| ABCC1;ABCC4 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0002376| immune system process IL2;IDO1 GO:0098869| GSR;ALB;CAT;PTGS1;GPX1;PTGS2 GO:0007568| aging CYP1A1;IL15;CAT;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;GPR18;PPARG;IL2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;ABCC4;SOD1;PTGS2;CYP1A2 GO:0050778| positive regulation of immune response IL15;PLA2G1B GO:0055085| transmembrane transport TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;SLC22A8;TRPV3;CACNA1H;SLC22A11;ABCC4;TRPV2 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;GPX1;NAAA;PTGS1;PON1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0048469| cell maturation IL15;PPARG GO:0045471| response to ethanol IL2;CAT;SOD1;CNR1;HMGCR;OPRM1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;ALOX15;IDO1;TRPV1;IL15 GO:0030217| T cell differentiation GPR18;IL2 GO:0006955| immune response IL15;IL2;OPRD1;CNR2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;IL2 GO:0046415| urate metabolic process SLC22A11;ABCG2 GO:0031667| response to nutrient levels SOD1;PON1;IL15 GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;IL15;PLA2G1B;CACNA1I GO:0070542| response to fatty acid CAT;PTGS2;PON1 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IL15 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;IL2;OPRM1;HTR2A GO:0050729| positive regulation of inflammatory response IL15;TRPV4;IL2 GO:0098656| SLC22A8;VDAC1;SLC22A6 GO:0046470| phosphatidylcholine metabolic process PON1;PLA2G1B GO:0001895| retina homeostasis ALB;SOD1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;TPMT GO:0006811| ion transport TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;SLC22A11;CHRNA7;TRPV3;CACNA1H;GLRA3;SLC22A8 GO:0009636| response to toxin CYP1A1;CYP1B1;PON1;SLC22A8;CAT;GPX1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;ABCC4;CYP1A2;PTGS2 18652:[DB14011 DB07280] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 18653:[DB14011 DB03182] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 18654:[DB14011 DB02021] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0022900| electron transport chain CYP1A2;AKR1B1;GSR;IDO1 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;AKR1B10;AKR1B1;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;AKR1B10;CYP2C9;CYP1A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0010033| response to organic substance AKR1B1;PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0001523| retinoid metabolic process AKR1B10;NAPEPLD 18655:[DB14011 DB02164] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02164|N-Sulfo-Flavin Mononucleotide HAO1 common genes common pathways GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;HAO1;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;HAO1;CYP1A2 18656:[DB14011 DB04616] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0009611| response to wounding CYP1A1;ACHE;GPX1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE 18657:[DB14011 DB03879] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03879|alpha-L-methyl-fucose MBL2 common genes common pathways GO:0050830| defense response to Gram-positive bacterium PLA2G1B;MBL2 GO:0045087| innate immune response PPARG;MBL2 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;MBL2 GO:0002376| immune system process MBL2;IDO1 18658:[DB14011 DB02220] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02220|AL7089A CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CA2;CYP1A1;PPARG;TRPA1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG 18659:[DB14011 DB13923] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13923|Emicizumab F9;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 18660:[DB14011 DB07128] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07128|N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINE F2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;F2;PPARG;GPR18 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 18661:[DB14011 DB14061] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14061|Hycanthone ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV1;VDAC1;ABCB1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0006810| transport TRPV1;ABCB1;CACNA1I;ABCG2;ABCC1;TRPV2 GO:0042493| response to drug ABCB1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;HTR2A;SOD1 18662:[DB14011 DB00112] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;HMGCR;OPRM1;VEGFA;HTR2A;GPR55 GO:0030855| epithelial cell differentiation PPARG;VDAC1;VEGFA GO:0045766| positive regulation of angiogenesis VEGFA;CHRNA7;CYP1B1 GO:0001541| ovarian follicle development VEGFA;SOD1 GO:0043406| positive regulation of MAP kinase activity VEGFA;HTR2A GO:0010628| positive regulation of gene expression TRPV4;VEGFA GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;VEGFA GO:0071456| cellular response to hypoxia VEGFA;PTGS2;OPRD1;SLC29A1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0002376| immune system process FCGR1A;FCGR2A;IDO1;C1QB;C1R;C1QA;C1QC GO:0030224| monocyte differentiation VEGFA;PPARG GO:0030324| lung development VEGFA;CYP1A2 GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0045087| innate immune response C1QC;C1QA;C1R;C1QB;PPARG;FCGR1A GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;VEGFA GO:0043312| neutrophil degranulation FCGR3B;FCGR2A;CAT;ALOX5 GO:0002576| platelet degranulation VEGFA;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0001822| kidney development CAT;VEGFA GO:0043066| negative regulation of apoptotic process GPX1;CAT;VEGFA;PTGS2;HMGCR;SOD1 GO:0051781| positive regulation of cell division CAT;VEGFA GO:0043117| positive regulation of vascular permeability TRPV4;VEGFA GO:0007165| signal transduction HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;FCGR2C;OPRD1;CHRNA7;PPARG;FCGR2B;GPR18;SMPD1;FCGR1A;PLA2G1B;CACNA1I GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2;GPX1 GO:0001934| positive regulation of protein phosphorylation VEGFA;CHRNA7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;VEGFA GO:0007595| lactation VEGFA;SLC29A1 GO:0006954| inflammatory response FCGR2B;TRPV1;IDO1;ALOX15;PTGS2;CNR2;PTGS1;ALOX5 GO:0006955| immune response C1QC;OPRD1;FCGR2C;FCGR3A;CNR2;FCGR2B;FCGR3B;C1R;FCGR1A GO:0016032| viral reproduction HTR2A;VDAC1;FCGR2B GO:0048469| cell maturation VEGFA;PPARG GO:0001525| angiogenesis CYP1B1;VEGFA;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;VEGFA GO:0007399| nervous system development VEGFA;GLRB;SMPD1 18663:[DB14011 DB05771] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05771|LLL-3348 IL10 common genes common pathways GO:1904706| IL10;PPARG GO:0006955| immune response CNR2;OPRD1;IL10 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL10 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;IDO1;ALOX15;TRPV1;IL10 GO:0051384| response to glucocorticoid stimulus IL10;PTGS2 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;IL10 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;IL10 GO:0032868| response to insulin stimulus TRPV4;IL10;CAT;AANAT GO:0014854| response to inactivity CAT;IL10 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;IL10 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;IL10 GO:0014823| response to activity IL10;CAT GO:0032496| response to lipopolysaccharide CYP1A1;IL10;IDO1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;IL10 GO:0035722| interleukin-12-mediated signaling pathway IL10;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IL10;PLA2G1B GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IL10 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;IL10;ABCC1;SMPD1 GO:0034465| response to carbon monoxide SOD1;IL10 GO:0050728| negative regulation of inflammatory response IL10;CNR2 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT;IL10;CYP1A1 GO:0030595| leukocyte chemotaxis IL10;CNR2 GO:0010468| regulation of gene expression IL10;CYP1A2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;IL10;CHRNA7 GO:0010033| response to organic substance IL10;CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0042130| negative regulation of T cell proliferation IL10;IDO1 18664:[DB14011 DB07470] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07470|(3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1I;MYH14;CACNA1G GO:0007605| sensory perception of sound MYH14;GPX1;SOD1 18665:[DB14011 DB12831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12831|Gabexate KLKB1;F2;PLG;PRSS1;C1S;C1R common genes common pathways GO:0002376| immune system process IDO1;C1R;C1S GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0009235| cobalamin metabolic process PRSS1;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;GPR18;PPARG;F2 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0051702| interaction with symbiont PLG;GPX1 GO:0045087| innate immune response PPARG;C1R;C1S GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0002576| platelet degranulation SOD1;PLG GO:0061844| PLA2G1B;F2 GO:0008285| negative regulation of cell proliferation PPARG;PLG;CYP1B1;PTGS2;OPRM1 GO:0006954| inflammatory response PTGS1;ALOX5;KLKB1;CNR2;PTGS2;IDO1;ALOX15;TRPV1 GO:0006955| immune response OPRD1;CNR2;C1R GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 18666:[DB14011 DB00001] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00001|Lepirudin F2 common genes common pathways GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;F2;GPR18;PPARG GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;F2 GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 18667:[DB14011 DB07333] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07333|N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE KDR common genes common pathways GO:0001525| angiogenesis PTGS2;KDR;CYP1B1 GO:0016032| viral reproduction HTR2A;KDR;VDAC1 GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0043066| negative regulation of apoptotic process KDR;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;KDR GO:0045766| positive regulation of angiogenesis CYP1B1;KDR;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;KDR;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 18668:[DB14011 DB07840] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways GO:0007420| brain development FGFR1;ACAT1 GO:0001525| angiogenesis PTGS2;FGFR1;CYP1B1 GO:0048469| cell maturation FGFR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;FGFR1 GO:0010629| negative regulation of gene expression OPRD1;FGFR1 GO:0010976| positive regulation of neuron projection development FGFR1;CNR1 GO:0010468| regulation of gene expression CYP1A2;FGFR1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FGFR1 GO:0048514| blood vessel morphogenesis CYP1B1;FGFR1 GO:0007605| sensory perception of sound FGFR1;SOD1;GPX1 GO:0043406| positive regulation of MAP kinase activity HTR2A;FGFR1 GO:0001657| ureteric bud development CAT;FGFR1 GO:0030324| lung development CYP1A2;FGFR1 GO:0042127| regulation of cell proliferation FGFR1;PTGS2;PTGS1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;TRPV4;TRPV1;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;FGFR1;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent FGFR1;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade FGFR1;GPX1 18669:[DB14011 DB05235] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0007605| sensory perception of sound CRYM;GPX1;SOD1 GO:0006810| transport TTR;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;THRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;THRA;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;CRYM;PPARG GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0007611| learning or memory CNR1;CHRNA7;THRA GO:0006367| transcription initiation from RNA polymerase II promoter THRA;PPARG GO:0006355| regulation of transcription, DNA-dependent THRA;PPARG GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;GPX1;PTGS1;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYM;CYP1B1 GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0009409| response to cold PPARG;TRPA1;THRA;TRPM8 GO:0001503| ossification THRA;ALOX15 GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter THRA;PPARG GO:0008016| regulation of heart contraction CACNA1H;THRA GO:0006351| transcription, DNA-dependent THRA;PPARG GO:0043401| steroid hormone mediated signaling pathway THRA;PPARG 18670:[DB14011 DB01295] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes CYP2D6 common pathways GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1;PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0035556| intracellular signal transduction ADRA1A;PLA2G1B GO:0009409| response to cold ADRB2;TRPM8;ADRB1;PPARG;TRPA1 GO:0001659| temperature homeostasis HTR2A;GPX1;TRPV1;ADRB1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0051100| negative regulation of binding CYP2D6 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPV1;TRPA1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;ADRA1A;CYP1B1 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0007165| signal transduction ADRB1;CACNA1I;ADRA1A;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;ADRB2 GO:0009725| response to hormone stimulus ADRA1A;ACAT1 GO:0045907| positive regulation of vasoconstriction ADRA1A;HTR2A;PTGS2 GO:0045453| bone resorption ADRB2;GPR55 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0006939| smooth muscle contraction ADRA1A;HTR2A GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ADRA1A;TRPV4;TRPV1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;DAGLA;CYP2D6;FAAH GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1 GO:0042493| response to drug ADRA1A;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ADRB2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ADRA1A GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0002024| diet induced thermogenesis ADRB2;TRPV1;TRPV4;ADRB1 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0007202| activation of phospholipase C activity ADRA1A;GPR55;HTR2A GO:0006915| apoptotic process VDAC1;ADRA1A;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;ALOX15;TRPV4;ADRA1A GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT;CYP1A1;ADRA1A GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;ADRB2;HTR1A;GPR55;ADRB1;ADRA1A;GPR18;PPARG 18671:[DB14011 DB08164] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A 18672:[DB14011 DB06655] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;GLP1R;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0071345| cellular response to cytokine stimulus TRPV1;MME GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion DPP4;GLP1R;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;GLP1R;TRPV1;TRPV4 GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0045777| positive regulation of blood pressure GLP1R;CNR1 GO:0008016| regulation of heart contraction CACNA1H;GLP1R GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;GLP1R GO:0019233| sensory perception of pain CNR1;HTR2A;PTGS2;CNR2;MME;OPRM1;OPRD1;TRPA1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GLP1R;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0001666| response to hypoxia DPP4;CYP1A1;CHRNA7;CAT GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0001822| kidney development CAT;MME GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043312| neutrophil degranulation MME;CAT;ALOX5 GO:0007611| learning or memory CNR1;CHRNA7;GLP1R GO:0043542| endothelial cell migration DPP4;CYP1B1 18673:[DB14011 DB05268] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05268|iCo-007 RAF1 common genes common pathways GO:0042060| wound healing ALOX15;OPRM1;RAF1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;RAF1;CAT;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;RAF1 GO:0006915| apoptotic process VDAC1;GPX1;RAF1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;RAF1;HMGCR;OPRM1;HTR2A;GPR55 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;RAF1;TRPV1;GLRB;GLRA1;TRPA1 GO:0001666| response to hypoxia RAF1;CHRNA7;CAT;CYP1A1 GO:0048538| thymus development SOD1;RAF1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;RAF1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;RAF1 GO:0007507| heart development RAF1;PPARG GO:0035556| intracellular signal transduction PLA2G1B;RAF1 GO:0008283| cell proliferation RAF1;HTR1A;GPX1;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;RAF1;PTGS2;OPRM1 GO:1902042| GPX1;RAF1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;RAF1;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;RAF1;PTGS2 18674:[DB14011 DB04539] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways GO:0098869| ALB;GSR;GPX1;PTGS1;CAT;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB GO:0002576| platelet degranulation ALB;SOD1 GO:0006694| steroid biosynthetic process HMGCR;CYP19A1;CYP17A1 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP19A1;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR GO:0022900| electron transport chain CYP19A1;GSR;IDO1;CYP1A2 GO:0001895| retina homeostasis SOD1;ALB GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 18675:[DB14011 DB04312] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04312|2,3-Difluorobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1;ADH1C;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 18676:[DB14011 DB04254] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04254|8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;HSP90AA1 GO:0009409| response to cold TRPA1;HSP90AA1;PPARG;TRPM8 GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;HSP90AA1;SMPD1;CACNA1I;PLA2G1B GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HSP90AA1 18677:[DB14011 DB00162] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes CYP1A1 common pathways GO:0001649| osteoblast differentiation RDH14;CAT GO:0007601| visual perception RBP3;RBP4;DHRS3;GLRA1;LRAT;CRYZ;RDH12;RLBP1;GLRB;RDH5;CYP1B1;RDH8 GO:0032502| developmental process CYP1A1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG GO:1900087| CYP1A1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;HPGDS;PTGS1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;HPGDS GO:0007420| brain development APOD;ACAT1 GO:0043010| camera-type eye development CYP1A1;ALDH1A2 GO:0048662| negative regulation of smooth muscle cell proliferation APOD;PPARG GO:0001895| retina homeostasis SOD1;ALB GO:0009624| response to nematode CYP1A1 GO:0001516| prostaglandin biosynthetic process HPGDS;PTGS1;PTGS2 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0008285| negative regulation of cell proliferation ALDH1A2;CYP1B1;PPARG;PTGS2;OPRM1 GO:0001523| retinoid metabolic process RDH11;RBP4;ALDH1A1;DHRS3;RBP3;NAPEPLD;RBP1;RLBP1;RDH5;RBP2;LRAT;RDH12 GO:0055088| lipid homeostasis PPARG;RBP1 GO:0017143| insecticide metabolic process CYP1A1 GO:0050896| response to stimulus RBP4;RDH5;RDH8;TRPM8;RLBP1;RDH12;LRAT;TRPA1 GO:0070988| demethylation CYP1A1 GO:0001889| liver development CYP1A1;ALDH1A2;ACAT1 GO:0048678| response to axon injury SOD1;APOD GO:0001525| angiogenesis PTGS2;APOD;CYP1B1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;RBP4;CAT GO:0009692| ethylene metabolic process CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP3A4 GO:0042572| retinol metabolic process DHRS4;ALDH1A2;RDH5;CYP1B1;RDH8;LRAT;ALDH1A3;RDH12;RDH13;RBP4;RDH11;RETSAT;ALDH1A1;DHRS3;RDH14 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;RBP3;APOD;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;HPGDS GO:0007507| heart development RBP4;PPARG GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP26A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1;ALDH1A2 GO:0006693| prostaglandin metabolic process PTGS1;HPGDS;PTGS2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0008152| metabolic process ALDH1A2;SMPD1;ALDH1A3;ALDH1A1;ACAT1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP26A1;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;ALDH1A3;CYP1B1;TRPV1;ALDH1A2;IDO1;PTGS2;SOD1;CNR1 GO:0009635| response to herbicide CYP1A1 GO:0019371| cyclooxygenase pathway PTGS2;HPGDS;PTGS1 GO:0048565| digestive tract development CYP1A1 GO:0060013| righting reflex GLRB;ALDH1A3;GLRA1 GO:0051289| protein homotetramerization CAT;ALDH1A3;TRPA1;CRYZ;TRPM8;TRPV1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0007568| aging CAT;NAPEPLD;HTR2A;SOD1;CNR1;APOD;PTGS2;HMGCR;CYP1A1 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;DHRS4;CYP2D6;CYP17A1;CYP3A5;CYP2C9;CYP1A1 GO:0009611| response to wounding CYP1A1;GPX1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;ALDH1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0010041| response to iron(III) ion CYP1A1 GO:0042574| retinal metabolic process CYP1B1;ALDH1A2;ALDH1A3;RDH11 GO:0098869| GSR;ALB;PTGS2;CAT;PTGS1;GPX1 GO:0042593| glucose homeostasis TRPV4;PPARG;RBP4;CNR1 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0051262| protein tetramerization DHRS4;HMGCR;CAT GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;ALDH1A2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0032526| response to retinoic acid PPARG;RBP4 GO:0030324| lung development ALDH1A2;CYP1A2;RBP4 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;CYP1A1;IDO1 GO:0000302| response to reactive oxygen species APOD;SOD1;CAT;GPX1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0034097| response to cytokine stimulus AANAT;PTGS2;ALDH1A2 GO:0043066| negative regulation of apoptotic process ALB;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0071300| cellular response to retinoic acid ALDH1A2;PPARG GO:0001822| kidney development CAT;ALDH1A2 GO:0009615| response to virus CYP1A1 GO:0007626| locomotory behavior SOD1;OPRM1;HPGDS;ALDH1A3 GO:0008284| positive regulation of cell proliferation ALDH1A2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0002576| platelet degranulation SOD1;ALB GO:0055114| oxidation-reduction process CYP17A1;ALDH1A2;ALOX15;CYP3A5;CYP2C19;GSR;DHRS4;IDO1;CYP2D6;CYP1B1;RDH8;RDH5;ALDH1A3;CYP2C9;CYP1A1;CRYZ;RDH12;RDH13;CAT;RDH11;PTGS1;ALOX5;GPX1;DHRS3;RETSAT;ALDH1A1;CYP3A4;SOD1;CYP26A1;CYP1A2;CYP3A7;RDH14;PTGS2;HMGCR GO:0006631| fatty acid metabolic process PTGS2;PTGS1;HPGDS;ALOX15 GO:0022900| electron transport chain DHRS3;CYP1A2;IDO1;GSR GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;APOD;SOD1;HTR2A;PTGS2;CYP1A2 GO:0033189| response to vitamin A CAT;ALDH1A2;CYP1A1;PPARG GO:0006694| steroid biosynthetic process HMGCR;RDH8;CYP17A1 GO:0009308| amine metabolic process CYP1A1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 18678:[DB14011 DB02643] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02643|N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate IGF1;MAOB common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;IGF1 GO:0042493| response to drug MAOB;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0022900| electron transport chain MAOB;IDO1;GSR;CYP1A2 GO:0007517| muscle organ development CACNA1H;IGF1 GO:0045893| positive regulation of transcription, DNA-dependent IGF1;PPARG GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;MAOB;CRYZ;CYP1A1;CYP2C9;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0002576| platelet degranulation IGF1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IGF1;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation IGF1;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043066| negative regulation of apoptotic process IGF1;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0032496| response to lipopolysaccharide IDO1;MAOB;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0010628| positive regulation of gene expression TRPV4;IGF1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;IGF1;PLA2G1B GO:0050714| positive regulation of protein secretion IGF1;PLA2G1B GO:0043388| positive regulation of DNA binding PPARG;IGF1 GO:0010468| regulation of gene expression IGF1;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;IGF1 GO:0009408| response to heat TRPV1;IGF1;TRPV2;TRPV3;SOD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IGF1 GO:0045445| myoblast differentiation HMGCR;IGF1 GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CAT;MAOB GO:0045821| positive regulation of glycolysis HTR2A;IGF1 GO:0045740| positive regulation of DNA replication PLA2G1B;IGF1 GO:0048146| positive regulation of fibroblast proliferation IGF1;PLA2G1B GO:0051450| myoblast proliferation GPX1;IGF1 GO:0008283| cell proliferation GPX1;HTR1A;IGF1;CYP1A1 GO:0009636| response to toxin CYP1A1;MAOB;CYP1B1;CAT;GPX1 GO:0010269| response to selenium ion GPX1;MAOB GO:0014065| phosphatidylinositol 3-kinase cascade IGF1;HTR2A GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;IGF1;SMPD1 GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0090201| negative regulation of release of cytochrome c from mitochondria IGF1;GPX1 GO:0040014| regulation of multicellular organism growth SOD1;IGF1 18679:[DB14011 DB07908] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways GO:0030838| positive regulation of actin filament polymerization ALOX15;PFN1 GO:0006357| regulation of transcription from RNA polymerase II promoter PFN1;PPARG 18680:[DB14011 DB06586] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06586|Cetilistat PNLIP common genes common pathways GO:0001523| retinoid metabolic process PNLIP;NAPEPLD GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;PNLIP;PTGS2;CYP1A2;HMGCR GO:0016042| lipid catabolic process PLA2G1B;DAGLA;NAPEPLD;PNLIP 18681:[DB14011 DB02684] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02684|5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine EPRS common genes common pathways GO:0008152| metabolic process EPRS;SMPD1;ACAT1 18682:[DB14011 DB00174] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0007565| female pregnancy IDO1;SLC38A3 GO:0031667| response to nutrient levels SOD1;ASNS GO:0016032| viral reproduction VDAC1;SLC1A5;HTR2A GO:0001889| liver development ACAT1;ASNS;CYP1A1 GO:0006811| ion transport TRPV2;SLC38A3;CHRNA7;CACNA1H;TRPV3;GLRA3;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0009636| response to toxin CYP1A1;CYP1B1;ASNS;CAT;GPX1 GO:0046718| entry of virus into host cell SLC1A5;HTR2A GO:0007420| brain development SLC38A3;ACAT1 GO:0032870| cellular response to hormone stimulus CACNA1H;ASNS GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;ASNS;HMGCR;PTGS2 GO:0009612| response to mechanical stimulus ASNS;TRPV4;PPARG GO:0055085| transmembrane transport CACNA1H;SLC16A10;TRPV3;TRPV2;SLC38A3;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1 GO:0043200| response to amino acid stimulus GLRB;ASNS;GLRA3 GO:0009416| response to light stimulus ASNS;AANAT 18683:[DB14011 DB06942] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06942|N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide F2 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;F2;GPR18;PPARG GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 18684:[DB14011 DB04873] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04873|Piboserod HTR4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;HTR4;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PPARG;GPR18 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;HTR4;CNR2;OPRM1;CNR1 GO:0007268| synaptic transmission CACNA1G;GLRA1;GLRB;VDAC1;HTR4;OPRM1;OPRD1;GLRA3;HTR2A GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;HTR4;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 18685:[DB14011 DB07046] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;MAP2K1 GO:0007507| heart development MAP2K1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;MAP2K1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;MAP2K1 GO:0010628| positive regulation of gene expression MAP2K1;TRPV4 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;MAP2K1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;MAP2K1 GO:0048538| thymus development MAP2K1;SOD1 18686:[DB14011 DB02999] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02999|Quisqualate GRIA2;GRIK2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential GRIA2;SLC29A1;CHRNA7;OPRM1;GRIK2;GLRA3;GLRB;TRPV1;GLRA1 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;GRIK2 GO:0006874| cellular calcium ion homeostasis CHRNA7;GRIK2;GPR12;HTR2A;TRPM8;TRPV4 GO:0042391| regulation of membrane potential GLRB;CACNA1G;GLRA1;CACNA1H;GRIK2 GO:0006810| transport ABCC1;ABCG2;CACNA1I;TRPV1;GRIK2;TRPV2 GO:0060080| regulation of inhibitory postsynaptic membrane potential GRIK2;GLRA1 GO:0034220| ion transmembrane transport CHRNA7;GRIA2;GRIK2;GLRA3;GLRB;TRPV1;GLRA1;TRPA1 GO:0055085| transmembrane transport TRPV2;GRIK2;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0019228| regulation of action potential in neuron CACNA1H;GRIK2;CACNA1I;CACNA1G GO:0007268| synaptic transmission GRIA2;GRIK2;GLRA3;HTR2A;OPRM1;OPRD1;VDAC1;GLRB;GLRA1;CACNA1G GO:0043524| negative regulation of neuron apoptosis GRIK2;SOD1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GRIA2 GO:0001662| behavioral fear response VDAC1;GRIK2;HTR1A GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;TRPV3;CACNA1H;GLRA3;GRIK2;GRIA2;TRPV2;CHRNA7 18687:[DB14011 DB02983] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02983|Para-Mercury-Benzenesulfonic Acid CLC;ESR2 common genes common pathways GO:0006351| transcription, DNA-dependent ESR2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2 GO:0046006| regulation of activated T cell proliferation IDO1;CLC GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;ESR2;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;ESR2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR2;TRPV1;TRPV4 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2 18688:[DB14011 DB01031] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01031|Ethinamate CA1;CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CA2;TRPA1;CYP1A1;PPARG 18689:[DB14011 DB06779] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;SELP;PTGS2;CNR2 GO:0007595| lactation SLC29A1;VEGFA;SERPINC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;VEGFA;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;VEGFA GO:0007399| nervous system development VEGFA;SMPD1;GLRB GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1;HPSE GO:0001525| angiogenesis CYP1B1;VEGFA;PTGS2 GO:0048469| cell maturation PPARG;VEGFA GO:0051781| positive regulation of cell division VEGFA;CAT GO:0007584| response to nutrient PPARG;HMGCR;CNR1;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0060055| angiogenesis involved in wound healing HPSE;GPX1 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2;OPRD1 GO:0043117| positive regulation of vascular permeability VEGFA;TRPV4 GO:0051897| positive regulation of protein kinase B signaling cascade HPSE;GPX1 GO:0030224| monocyte differentiation PPARG;VEGFA GO:0002576| platelet degranulation VEGFA;SOD1;SELP GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;VEGFA GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;VEGFA;PTGS2;HMGCR;CHRNA7 GO:0001822| kidney development VEGFA;CAT GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;VEGFA;SOD1 GO:0007155| cell adhesion SELP;HPSE;CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;TRPV4;TRPV1 GO:0043312| neutrophil degranulation HPSE;CAT;ALOX5 GO:0042060| wound healing ALOX15;HPSE;OPRM1 GO:0032496| response to lipopolysaccharide SELP;CNR1;CYP1A2;OPRM1;PTGS2;CNR2;IDO1;TFPI;CYP1A1 GO:0030324| lung development CYP1A2;VEGFA GO:0001666| response to hypoxia CAT;CHRNA7;VEGFA;CYP1A1 GO:0010628| positive regulation of gene expression VEGFA;TRPV4 GO:0043406| positive regulation of MAP kinase activity VEGFA;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;VEGFA;OPRM1;HMGCR;GPR55;HTR2A GO:0030855| epithelial cell differentiation VEGFA;PPARG;VDAC1 GO:0001541| ovarian follicle development SOD1;VEGFA GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;VEGFA GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;TFPI GO:0071456| cellular response to hypoxia VEGFA;PTGS2;OPRD1;SLC29A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;SELP 18690:[DB14011 DB11937] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration GPR35;TRPV1;TRPV4;HTR2A;OPRM1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR35;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0009636| response to toxin CAT;GPX1;CYP1A1;AHR;CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AHR GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;AHR;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;GPR35;PPARG;GPR18 GO:0010468| regulation of gene expression CYP1A2;AHR GO:0035025| positive regulation of Rho protein signal transduction GPR18;GPR35;GPR55 GO:0006915| apoptotic process GPX1;VDAC1;AHR GO:0048511| rhythmic process AANAT;PPARG;AHR GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR35;GPR18;GPR55 GO:0045892| negative regulation of transcription, DNA-dependent AHR;PPARG GO:0009410| response to xenobiotic stimulus GPX1;AHR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AHR GO:0006355| regulation of transcription, DNA-dependent AHR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AHR 18691:[DB14011 DB06159] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06159|Rubitecan TOP1 common genes common pathways GO:0007623| circadian rhythm TOP1;AANAT GO:0042493| response to drug CYP1A2;PTGS2;TOP1;SOD1;HTR2A;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0048511| rhythmic process PPARG;TOP1;AANAT GO:0016032| viral reproduction TOP1;HTR2A;VDAC1 18692:[DB14011 DB05501] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CXCR4;GPR18;CCR5;PPARG;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0006915| apoptotic process GPX1;CXCR4;VDAC1 GO:0000187| activation of MAPK activity PLA2G1B;CXCR4;SOD1;CHRNA7 GO:0001666| response to hypoxia CYP1A1;CXCR4;CAT;CHRNA7 GO:0048714| positive regulation of oligodendrocyte differentiation CXCR4;PPARG GO:0009615| response to virus CXCR4;CYP1A1 GO:0071345| cellular response to cytokine stimulus CXCR4;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration CXCR4;TRPV1;TRPV4;CCR5;HTR2A;OPRM1 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;CXCR4;SMPD1;PPARG;CCR5;GPR18 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CCR5;TRPV1 GO:0006954| inflammatory response CCR5;TRPV1;IDO1;CXCR4;ALOX15;CNR2;PTGS2;PTGS1;ALOX5 GO:0006955| immune response CCR5;CNR2;OPRD1 GO:0006816| calcium ion transport CCR5;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0016032| viral reproduction HTR2A;CCR5;VDAC1;CXCR4 18693:[DB14011 DB07771] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07771|[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID KRAS;FNTA;FNTB common genes common pathways GO:0043406| positive regulation of MAP kinase activity KRAS;HTR2A GO:0010628| positive regulation of gene expression TRPV4;KRAS GO:0035900| response to isolation stress NAPEPLD;KRAS GO:0042127| regulation of cell proliferation PTGS1;PTGS2;FNTB GO:0032228| regulation of synaptic transmission, GABAergic KRAS;CNR1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;KRAS;CHRNA7 GO:0051384| response to glucocorticoid stimulus PTGS2;KRAS GO:0007165| signal transduction CHRNA7;KRAS;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0001934| positive regulation of protein phosphorylation KRAS;CHRNA7 GO:0007565| female pregnancy KRAS;IDO1 GO:0043524| negative regulation of neuron apoptosis KRAS;SOD1 GO:0008542| visual learning KRAS;HMGCR GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;KRAS;PLA2G1B GO:0001889| liver development CYP1A1;KRAS;ACAT1 18694:[DB14011 DB03839] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03839|D-Tyrosine SLC16A10 common genes common pathways GO:0055085| transmembrane transport TRPV2;TRPV3;SLC16A10;CACNA1H;TRPM8;ABCG2;TRPV1;CACNA1I;TRPV4;VDAC1;TRPA1;ABCC1;CACNA1G 18695:[DB14011 DB02400] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02400|5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0007568| aging NQO1;CYP1A1;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;NQO1 GO:0006979| response to oxidative stress NQO1;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;NQO1 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;NQO1;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0006801| superoxide metabolic process NQO1;SOD1 GO:0006809| nitric oxide biosynthetic process NQO1;CYP1B1 GO:0009636| response to toxin NQO1;CYP1A1;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;NQO1;PPARG;CYP1A1;TRPA1 GO:0007584| response to nutrient NQO1;PPARG;HMGCR;CNR1 GO:0070301| cellular response to hydrogen peroxide NQO1;CYP1B1 GO:0045471| response to ethanol NQO1;SOD1;CNR1;HMGCR;OPRM1;CAT GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;NQO1;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0019430| removal of superoxide radicals SOD1;NQO1 18696:[DB14011 DB06862] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways GO:0006919| activation of caspase activity PPARG;CASP3 GO:0009411| response to UV CAT;CASP3 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;CASP3;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;CASP3;PTGS2;SOD1;CNR1 GO:0042542| response to hydrogen peroxide TRPA1;CAT;CASP3;GPX1;SOD1 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0007507| heart development CASP3;PPARG GO:0045165| cell fate commitment PPARG;CASP3 GO:0001666| response to hypoxia CYP1A1;CASP3;CAT;CHRNA7 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CASP3;CYP1A1;PPARG;TRPA1 GO:0043200| response to amino acid stimulus GLRA3;CASP3;GLRB GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0006915| apoptotic process VDAC1;GPX1;CASP3 GO:0007605| sensory perception of sound GPX1;CASP3;SOD1 GO:0009611| response to wounding CYP1A1;CASP3;GPX1 GO:0032355| response to estradiol stimulus CAT;CASP3;CYP1A2;PTGS2 GO:0035094| response to nicotine CHRNA7;CASP3;CNR1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CASP3;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0071407| cellular response to organic cyclic compound CASP3;CYP1B1;CYP1A1 GO:0046677| response to antibiotic SOD1;CASP3;CYP1A1 GO:0043066| negative regulation of apoptotic process CAT;CASP3;GPX1;SOD1;HMGCR;PTGS2 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0042060| wound healing OPRM1;CASP3;ALOX15 GO:0032496| response to lipopolysaccharide CASP3;PTGS2;CNR2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0007611| learning or memory CHRNA7;CASP3;CNR1 18697:[DB14011 DB06492] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06492|Mirococept C3 common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;C3 GO:0045087| innate immune response PPARG;C3 GO:0006631| fatty acid metabolic process C3;PTGS2;PTGS1;ALOX15 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;C3;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0002376| immune system process IDO1;C3 GO:0045766| positive regulation of angiogenesis C3;CHRNA7;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production C3;PTGS2;CYP1B1 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;C3;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0001934| positive regulation of protein phosphorylation C3;CHRNA7 GO:0006955| immune response C3;CNR2;OPRD1 GO:0006954| inflammatory response ALOX5;PTGS1;C3;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;C3;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1 18698:[DB14011 DB04125] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04125|N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18699:[DB14011 DB01426] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;ORM1;GPR18 GO:0086002| SCN5A;CACNA1G GO:0055085| transmembrane transport CACNA1H;TRPV3;SCN5A;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0086016| SCN5A;CACNA1G GO:0043312| neutrophil degranulation ORM1;ALOX5;CAT GO:0086015| SCN5A;CACNA1G GO:0002576| platelet degranulation SOD1;ORM1 GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0086045| CACNA1G;SCN5A GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;GLRA3;TRPV3;CACNA1H;CHRNA7;SCN5A;TRPV2 GO:0086046| CACNA1G;SCN5A GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN5A;CACNA1G GO:0019228| regulation of action potential in neuron CACNA1G;CACNA1I;CACNA1H;SCN5A GO:0035725| sodium ion transmembrane transport SCN5A;CACNA1H;CACNA1I;CACNA1G GO:0071277| cellular response to calcium ion ALOX15;SCN5A GO:0086091| SCN5A;CACNA1G GO:0002027| regulation of heart rate CACNA1G;SCN5A GO:0086010| CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;ORM1;TRPV1;IDO1;ALOX15 18700:[DB14011 DB04551] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1;PKLR GO:0008152| metabolic process SMPD1;PKLR;ACAT1 GO:0007584| response to nutrient PPARG;PKLR;CNR1;HMGCR GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PKLR GO:0010226| response to lithium ion PKLR;PTGS2 GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;SLCO2A1;ABCC1;CACNA1G;TRPV2;TRPV3;CACNA1H GO:0051591| response to cAMP AANAT;PKLR GO:0001666| response to hypoxia CHRNA7;CAT;PKLR;CYP1A1 18701:[DB14011 DB12520] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12520|Plozalizumab CCR2 common genes common pathways GO:0016525| negative regulation of angiogenesis PPARG;CCR2 GO:0009611| response to wounding CYP1A1;CCR2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CCR2;GPR18;PPARG GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;CCR2;GPR12;HTR2A GO:0007194| negative regulation of adenylate cyclase activity CCR2;OPRM1 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1;CCR2 GO:0006954| inflammatory response CCR2;ALOX5;PTGS1;CNR2;PTGS2;ALOX15;IDO1;TRPV1 GO:0006955| immune response CCR2;OPRD1;CNR2 GO:0016032| viral reproduction HTR2A;CCR2;VDAC1 GO:0050729| positive regulation of inflammatory response CCR2;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;OPRM1;CCR2 GO:0007165| signal transduction CCR2;CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG 18702:[DB14011 DB07658] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07658|AC-(D)PHE-PRO-BOROLYS-OH F2 common genes common pathways GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0008284| positive regulation of cell proliferation F2;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 18703:[DB14011 DB07558] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways GO:0016032| viral reproduction VDAC1;PSMA7;HTR2A GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV1;VDAC1;TRPV4;CACNA1I;TRPA1;PSMA7;ABCC1;CACNA1G 18704:[DB14011 DB08830] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways GO:0015758| glucose transport PLA2G1B;SLC2A1 GO:0055085| transmembrane transport TRPV2;CACNA1H;SLC2A1;TRPV3;ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0042908| xenobiotic transport SLC2A1;ABCG2;ABCC1 GO:0050796| regulation of insulin secretion CNR1;SLC2A1 GO:0032868| response to insulin stimulus SLC2A1;CAT;AANAT;TRPV4 GO:0071260| cellular response to mechanical stimulus SLC2A1;PTGS2 GO:0006970| response to osmotic stress SLC2A1;TRPV4 GO:0007565| female pregnancy IDO1;SLC2A1 18705:[DB14011 DB07958] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2E GO:0036150| PLA2G2E;PLA2G1B GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;PTGS1;NAAA;GPX1;PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;PLA2G2E GO:0036148| PLA2G1B;PLA2G2E GO:0036149| PLA2G1B;PLA2G2E GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PLA2G2E;PTGS2;CNR2;ALOX5;PTGS1 GO:0036152| PLA2G2E;PLA2G1B GO:0006644| phospholipid metabolic process PLA2G1B;PLA2G2E;NAPEPLD GO:0016042| lipid catabolic process NAPEPLD;PLA2G2E;PLA2G1B;DAGLA GO:0006654| phosphatidic acid biosynthetic process PLA2G2E;PLA2G1B GO:0036151| PLA2G1B;PLA2G2E 18706:[DB14011 DB04850] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;MAOA;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;SLCO1B1;CACNA1H;TRPV3;TRPV2 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLCO1B1;CACNA1H;TRPV3;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPA1;GLRA1;CACNA1G 18707:[DB14011 DB05142] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05142|ND7001 PDE2A;PDE2A common genes common pathways GO:0030224| monocyte differentiation PPARG;PDE2A GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PDE2A;TRPV4;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;PPARG;GPR18;PDE2A GO:0071260| cellular response to mechanical stimulus PTGS2;PDE2A GO:0008152| metabolic process PDE2A;SMPD1;ACAT1 GO:0043117| positive regulation of vascular permeability TRPV4;PDE2A GO:0050729| positive regulation of inflammatory response PDE2A;TRPV4 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PDE2A;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0070588| calcium ion transmembrane transport TRPM8;TRPV1;CACNA1I;TRPV4;TRPA1;PDE2A;CACNA1G;CHRNA7;TRPV2;TRPV3;OPRM1;CACNA1H 18708:[DB14011 DB08949] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08949|Inositol nicotinate HCAR3;HCAR2;ATP5B;DGAT2;SLC5A8 common genes common pathways GO:0001525| angiogenesis PTGS2;ATP5B;CYP1B1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;NAAA;PTGS1;GPX1;CYP2C9;PPARG;ATP5B;DGAT2;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B GO:0042572| retinol metabolic process CYP1B1;DGAT2 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;TRPV1;SLC5A8;VDAC1;TRPV4;GLRB;CACNA1I;TRPA1;GLRA1;ATP5B;CACNA1G GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;SLC5A8 GO:0001649| osteoblast differentiation CAT;ATP5B GO:0007165| signal transduction HCAR2;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CACNA1I;PLA2G1B;HCAR3;SMPD1;PPARG;GPR18 GO:0006915| apoptotic process SLC5A8;VDAC1;HCAR2;GPX1 GO:0055085| transmembrane transport SLC5A8;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HCAR3;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;HCAR2 18709:[DB14011 DB06266] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0006821| chloride transport GLRB;CFTR;GLRA1;GLRA3 GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CFTR;CACNA1G;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1 GO:0008152| metabolic process HK1;SMPD1;ACAT1 GO:0071320| cellular response to cAMP CFTR;AANAT GO:1902476| GLRA3;GLRB;GLRA1;CFTR GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CFTR;CACNA1G;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2 GO:0050891| multicellular organismal water homeostasis TRPV4;CFTR GO:0006695| cholesterol biosynthetic process CFTR;HMGCR GO:0099133| ABCC1;CFTR 18710:[DB14011 DB04724] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04724|(S)-2-((S)-3-ISOBUTYL-2,5-DIOXO-4-QUINOLIN-3-YLMETHYL-[1,4]DIAZEPAN-1YL)-N-METHYL-3-NAPHTALEN-2-YL-PROPIONAMIDE ITGAL common genes common pathways GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;ITGAL;PTGS1;ALOX5 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;ITGAL;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0043312| neutrophil degranulation ITGAL;ALOX5;CAT GO:0007155| cell adhesion CYP1B1;ITGAL 18711:[DB14011 DB04858] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0010193| response to ozone CYP2E1;CAT GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1A1;CYP2C9;HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;CYP2E1;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP3A4;CYP2E1;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol SOD1;CNR1;CYP2E1;HMGCR;OPRM1;CAT 18712:[DB14011 DB03348] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03348|Huperzine B ACHE common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;ACHE;HTR1A GO:0007399| nervous system development ACHE;SMPD1;GLRB GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE 18713:[DB14011 DB05930] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05930|SB-559448 MPL common genes common pathways GO:0008283| cell proliferation GPX1;MPL;HTR1A;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;MPL 18714:[DB14011 DB02742] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02742|Kifunensine MAN2A1;MAN1B1 common genes common pathways GO:0001889| liver development CYP1A1;MAN2A1;ACAT1 GO:0008152| metabolic process SMPD1;MAN2A1;MAN1B1;ACAT1 GO:0050769| positive regulation of neurogenesis MAN2A1;OPRM1 18715:[DB14011 DB01864] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways GO:0030838| positive regulation of actin filament polymerization ARF6;ALOX15 GO:0007155| cell adhesion ARF6;CYP1B1 GO:0051262| protein tetramerization HMGCR;TGM3;CAT GO:0045773| positive regulation of axon extension TRPV2;RAB11A GO:0001889| liver development ARF6;CYP1A1;ACAT1 GO:0007399| nervous system development SMPD1;GLRB;ARF6 18716:[DB14011 DB07528] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07528|3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one KDR common genes common pathways GO:0016032| viral reproduction KDR;VDAC1;HTR2A GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0001525| angiogenesis KDR;CYP1B1;PTGS2 GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;KDR;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;KDR GO:0043066| negative regulation of apoptotic process KDR;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0008284| positive regulation of cell proliferation KDR;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 18717:[DB14011 DB02071] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02071|WAY-151693 MMP13 common genes common pathways GO:0030282| bone mineralization ALOX15;MMP13;PTGS2 18718:[DB14011 DB05457] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05457|OSI-7904L TYMS common genes common pathways GO:0007568| aging CYP1A1;TYMS;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;TYMS GO:0033189| response to vitamin A PPARG;CYP1A1;TYMS;CAT GO:0007623| circadian rhythm AANAT;TYMS GO:0032259| methylation TYMS;CYP1A2 GO:0034097| response to cytokine stimulus AANAT;PTGS2;TYMS GO:0014070| response to organic cyclic compound CYP1A1;TYMS;PPARG;TRPA1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0009636| response to toxin CAT;GPX1;CYP1B1;CYP1A1;TYMS GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;TYMS 18719:[DB14011 DB02032] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways GO:0007283| spermatogenesis ACE;SOD1;CNR1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0001822| kidney development CAT;ACE GO:0008217| regulation of blood pressure SOD1;PTGS2;ACE;PTGS1;PPARG GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0060047| heart contraction SOD1;ACE;GPX1 18720:[DB14011 DB04489] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 18721:[DB14011 DB11081] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11081|Aluminum chloride GLUD1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1;PTGS1;ALOX5;GPX1;CAT;GLUD1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 18722:[DB14011 DB09295] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1G;CLCNKA;TRPA1;GLRA1 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;CLCNKA;CACNA1H GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0006821| chloride transport GLRA1;CLCNKA;GLRB;GLRA3 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:1902476| GLRA3;GLRA1;CLCNKA;GLRB GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;CLCNKA;VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0034220| ion transmembrane transport GLRB;TRPV1;GLRA1;TRPA1;CLCNKA;CHRNA7;GLRA3 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0007568| aging CYP1A1;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CAT GO:0030282| bone mineralization PTGS2;ALOX15 GO:0006810| transport ABCC1;CLCNKA;TRPV1;CACNA1I;ABCG2;TRPV2 GO:0046697| decidualization PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:1902219| PTGS2 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0098869| GSR;PTGS2;PTGS1;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0009750| response to fructose stimulus PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0071284| cellular response to lead ion PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2 18723:[DB14011 DB06011] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06011|AMG-222 DPP4 common genes common pathways GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 18724:[DB14011 DB07711] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07711|(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol ADA common genes common pathways GO:0007568| aging CAT;ADA;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CYP1A1 GO:0001666| response to hypoxia CHRNA7;CAT;ADA;CYP1A1 GO:0007155| cell adhesion CYP1B1;ADA GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;ADA;GPX1;CAT GO:0030324| lung development ADA;CYP1A2 GO:0033197| response to vitamin E CAT;ADA GO:0043278| response to morphine CNR1;OPRM1;ADA GO:0050728| negative regulation of inflammatory response CNR2;ADA GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ADA;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0001890| placenta development PPARG;SOD1;ADA GO:0042542| response to hydrogen peroxide CAT;ADA;GPX1;SOD1;TRPA1 GO:0001889| liver development ACAT1;ADA;CYP1A1 18725:[DB14011 DB00811] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes SLC29A1 common pathways GO:0006195| purine nucleotide catabolic process GPX1;NT5C2 GO:0007595| lactation SLC29A1 GO:0006955| immune response OPRD1;CNR2;ENPP1 GO:0015858| nucleoside transport SLC29A1 GO:0051289| protein homotetramerization TRPM8;TRPV1;CRYZ;TRPA1;CAT;IMPDH2 GO:0030431| sleep SLC29A1;HTR2A;CACNA1I GO:0015862| uridine transport SLC29A1 GO:0008152| metabolic process ENPP1;SMPD1;NT5C2;ACAT1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1 GO:0032869| cellular response to insulin stimulus PLA2G1B;ENPP1;PPARG GO:0055114| oxidation-reduction process CYP3A4;IMPDH2;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1;IMPDH1;CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1 GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0030308| negative regulation of cell growth PPARG;ENPP1 GO:0007623| circadian rhythm IMPDH2;AANAT GO:0043312| neutrophil degranulation IMPDH1;CAT;ALOX5;IMPDH2 GO:1901642| SLC29A1;SLC28A3 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;NT5C2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 18726:[DB14011 DB08098] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08098|{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid AKR1B1 common genes common pathways GO:0010033| response to organic substance TRPA1;AKR1B1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;AKR1B1 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;AKR1B1 GO:0022900| electron transport chain CYP1A2;AKR1B1;GSR;IDO1 GO:0055114| oxidation-reduction process AKR1B1;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 18727:[DB14011 DB00577] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0009636| response to toxin CAT;GPX1;SLC6A14;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport TRPV3;CACNA1H;SLC22A8;GLRA3;SLC15A2;TRPV2;CHRNA7;CACNA1G;SLC15A1;GLRA1;TRPA1;SLC10A2;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0006810| transport ABCC1;SLC15A1;SLC10A2;CACNA1I;TRPV1;ABCG2;SLC15A2;SLC6A14;TRPV2 GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC15A2;SLC22A8;SLC6A14;TRPV2;CACNA1G;SLC22A6;ABCC1;TRPA1;SLC15A1;CACNA1I;TRPV4;VDAC1;TRPV1;SLC10A2;ABCG2;TRPM8 18728:[DB14011 DB00699] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00699|Nicergoline ADRA1A;CYP2D6 common genes CYP2D6 common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0051100| negative regulation of binding CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0035556| intracellular signal transduction ADRA1A;PLA2G1B GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;ADRA1A;OPRM1;PTGS2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;ADRA1A;TRPV1;HTR2A;OPRM1 GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2;HTR2A GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CACNA1I;ADRA1A;PLA2G1B;SMPD1;PPARG;GPR18 GO:0009725| response to hormone stimulus ADRA1A;ACAT1 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ADRA1A;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process CYP1B1;DAGLA;CYP2D6;ALOX15;FAAH GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRM1;OPRD1;HTR2A GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0006915| apoptotic process VDAC1;ADRA1A;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0007202| activation of phospholipase C activity ADRA1A;GPR55;HTR2A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;ADRA1A;PPARG;GPR18 GO:0007568| aging CAT;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;ADRA1A;CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1;CYP2C9 18729:[DB14011 DB05678] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05678|SLx-4090 MTTP common genes common pathways GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;MTTP;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9 18730:[DB14011 DB01397] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes PTGS1;PTGS2 common pathways GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0002576| platelet degranulation SOD1;ALB GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0009750| response to fructose stimulus PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR;ALB GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1 GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPA1;TRPV1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG;PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0050727| regulation of inflammatory response PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;PTGS2;CNR2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0042633| hair cycle PTGS2 GO:0001895| retina homeostasis ALB;SOD1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 18731:[DB14011 DB06755] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06755|Beta carotene BCO1;VLDLR;RBP1;RBP2;RBP3;RBP4;RBP5 common genes common pathways GO:0008203| cholesterol metabolic process CAT;VLDLR;HMGCR GO:0032526| response to retinoic acid RBP4;PPARG GO:0030324| lung development RBP4;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;VLDLR GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;BCO1 GO:0008202| steroid metabolic process VLDLR;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0042593| glucose homeostasis TRPV4;PPARG;RBP4;CNR1 GO:0042574| retinal metabolic process CYP1B1;BCO1 GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT;RBP4 GO:0007399| nervous system development GLRB;SMPD1;VLDLR GO:0007507| heart development PPARG;RBP4 GO:0042572| retinol metabolic process RBP4;CYP1B1;BCO1 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG;NAAA;GPX1;PTGS1;HMGCR;CYP1A2;PTGS2;RBP3;VLDLR;NAPEPLD;CYP3A4 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A;VLDLR GO:0007601| visual perception RBP3;RBP4;GLRA1;CRYZ;GLRB;CYP1B1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;VLDLR;GPR55;CHRNA7 GO:0050896| response to stimulus TRPM8;TRPA1;RBP4 GO:0001523| retinoid metabolic process RBP4;RBP1;NAPEPLD;RBP3;RBP2;BCO1 GO:0055088| lipid homeostasis RBP1;PPARG 18732:[DB14011 DB01017] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes ALOX5 common pathways GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0035094| response to nicotine CASP3;CHRNA7;CNR1 GO:0006691| leukotriene metabolic process ALOX5;ALOX15;ABCC1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CASP3;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0071407| cellular response to organic cyclic compound IL1B;CYP1B1;CYP1A1;CASP3 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IL1B GO:0030224| monocyte differentiation VEGFA;PPARG GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;CYCS;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1A1;CYP2C9;CRYZ GO:0046677| response to antibiotic CYP1A1;SOD1;CASP3 GO:0002576| platelet degranulation SOD1;VEGFA GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;VEGFA;HMGCR;HTR1A;HTR2A;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;IL1B;PLA2G1B GO:0001822| kidney development CAT;VEGFA GO:0043066| negative regulation of apoptotic process MMP9;HMGCR;PTGS2;VEGFA;SOD1;CASP3;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;TRPV4;TRPV1;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;MMP9 GO:0042060| wound healing OPRM1;CASP3;ALOX15 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CASP3;CASP1;CYP1A1;IL1B;IDO1 GO:0007611| learning or memory CNR1;CHRNA7;CASP3 GO:0030324| lung development CYP1A2;VEGFA GO:0034599| cellular response to oxidative stress GPX1;CAT;CYCS;SOD1;GSR GO:0046330| positive regulation of JNK cascade TRPV4;IL1B GO:0071639| positive regulation of monocyte chemotactic protein-1 production TRPV4;IL1B GO:0001660| fever generation TRPV1;IL1B GO:0001666| response to hypoxia CYP1A1;CASP1;VEGFA;CAT;CHRNA7;CASP3 GO:0010628| positive regulation of gene expression VEGFA;TRPV4;IL1B GO:0043406| positive regulation of MAP kinase activity VEGFA;HTR2A GO:0043407| negative regulation of MAP kinase activity SMPD1;IL1B;HMGCR GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CASP3;TRPA1;PPARG;CYP1A1 GO:2001300| ALOX5 GO:0043200| response to amino acid stimulus GLRA3;CASP3;GLRB GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0055085| transmembrane transport TRPV2;SLC22A7;SLC22A11;CACNA1H;TRPV3;SLC22A8;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;SLC22A6;ABCC1;TRPA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;VEGFA;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0006915| apoptotic process CYCS;CASP3;GPX1;CASP1;VDAC1;IL1B GO:0030855| epithelial cell differentiation VDAC1;PPARG;VEGFA GO:0000187| activation of MAPK activity CHRNA7;SOD1;IL1B;PLA2G1B GO:0001541| ovarian follicle development SOD1;VEGFA GO:0045766| positive regulation of angiogenesis VEGFA;CHRNA7;IL1B;CYP1B1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0043388| positive regulation of DNA binding MMP9;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;IL1B;TRPV1 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0007605| sensory perception of sound SOD1;CASP3;GPX1 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0032355| response to estradiol stimulus CASP3;CAT;PTGS2;CYP1A2 GO:0009611| response to wounding GPX1;CASP3;CYP1A1 GO:0071456| cellular response to hypoxia SLC29A1;VEGFA;PTGS2;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;IL1B GO:0006954| inflammatory response IL1B;IDO1;ALOX15;TRPV1;ALOX5;PTGS1;CNR2;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL1B GO:0006955| immune response OPRD1;CNR2;IL1B GO:0007595| lactation VEGFA;SLC29A1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;VEGFA GO:2000778| positive regulation of interleukin-6 secretion IL1B;TRPV4 GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA;GPX1 GO:0001934| positive regulation of protein phosphorylation IL1B;MMP9;CHRNA7;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0050727| regulation of inflammatory response PTGS2;CASP1 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;MMP9;PPARG GO:0042542| response to hydrogen peroxide SOD1;CASP3;GPX1;CAT;TRPA1 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0001503| ossification ALOX15;MMP9 GO:0007507| heart development CASP3;PPARG GO:0045165| cell fate commitment CASP3;PPARG GO:0007399| nervous system development VEGFA;GLRB;SMPD1 GO:0071260| cellular response to mechanical stimulus IL1B;CASP1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;VEGFA GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1;IL1B GO:0001525| angiogenesis CYP1B1;VEGFA;PTGS2 GO:0048469| cell maturation PPARG;VEGFA GO:0031622| positive regulation of fever generation IL1B;CNR1;PTGS2 GO:0051781| positive regulation of cell division IL1B;VEGFA;CAT GO:0071276| cellular response to cadmium ion MMP9;CYP1A2;SOD1 GO:0098656| SLC22A6;VDAC1;SLC22A8;SLC22A7 GO:0008285| negative regulation of cell proliferation CYP1B1;IL1B;PPARG;OPRM1;PTGS2 GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0045333| cellular respiration CYCS;CYP1A2 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1H;TRPV3;SLC22A8;GLRA3;TRPV2;SLC22A7;SLC22A11;CHRNA7 GO:0009411| response to UV CAT;CASP3 GO:0006919| activation of caspase activity CASP3;PPARG;CASP1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;CASP3;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;IL1B GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2;OPRD1 GO:0007165| signal transduction CASP1;GPR18;PPARG;SMPD1;IL1B;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0007566| embryo implantation IL1B;MMP9;SOD1;PTGS2 GO:0050796| regulation of insulin secretion IL1B;CNR1 GO:0043117| positive regulation of vascular permeability TRPV4;VEGFA 18733:[DB14011 DB02871] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02871|3-Butylthiolane 1-Oxide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CAT;ADH1C;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP1A1;CYP2C9;CRYZ 18734:[DB14011 DB07397] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07397|(5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 18735:[DB14011 DB03283] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03283|beta-L-fucose ACHE common genes common pathways GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development ACHE;CACNA1H GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0051262| protein tetramerization CAT;HMGCR;ACHE GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 18736:[DB14011 DB03712] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03712|RU85053 SRC common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;SRC;ALOX15;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process SRC;IDO1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;SRC;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0016236| macroautophagy SRC;VDAC1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0045087| innate immune response PPARG;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;SRC GO:0009615| response to virus CYP1A1;SRC GO:0008283| cell proliferation HTR1A;SRC;GPX1;CYP1A1 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0070542| response to fatty acid CAT;SRC;PTGS2 GO:0007165| signal transduction CHRNA7;SRC;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0045453| bone resorption SRC;GPR55 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0031667| response to nutrient levels SOD1;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;SRC GO:0042542| response to hydrogen peroxide GPX1;SRC;CAT;SOD1;TRPA1 18737:[DB14011 DB04203] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04203|3-Mercuri-4-Aminobenzenesulfonamide CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;CYP1A2;PTGS2;SOD1 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 18738:[DB14011 DB01728] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01728|3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-Glycerol RHO common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;RHO;PPARG;GPR18 GO:0009416| response to light stimulus RHO;AANAT GO:0007165| signal transduction SMPD1;RHO;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 GO:0007601| visual perception GLRB;CYP1B1;GLRA1;CRYZ;RHO GO:0050896| response to stimulus TRPA1;RHO;TRPM8 GO:0001523| retinoid metabolic process NAPEPLD;RHO 18739:[DB14011 DB03417] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03417|1-(4-Tert-Butylcarbamoyl-Piperazine-1-Carbonyl)-3-(3-Guanidino-Propyl)-4-Oxo-Azetidine-2-Carboxylic Acid PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18740:[DB14011 DB02391] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0006955| immune response CNR2;OPRD1;PNP GO:0042493| response to drug ABCG2;CYP1A1;PNP;PPARG;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0043312| neutrophil degranulation CAT;ALOX5;PNP 18741:[DB14011 DB02020] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02020|Alrestatin AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;AKR1B1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;AKR1B1;CRYZ GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;AKR1B1;CYP1A2;PTGS2;SOD1 18742:[DB14011 DB02497] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02497|L-Alpha-Glycerophosphorylserine ANXA5 common genes common pathways GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;ANXA5;CHRNA7 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1;ANXA5 GO:0002576| platelet degranulation SOD1;ANXA5 GO:0043066| negative regulation of apoptotic process CAT;GPX1;ANXA5;SOD1;PTGS2;HMGCR 18743:[DB14011 DB14498] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14498|Potassium acetate ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;ATP1A1;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8 GO:0008217| regulation of blood pressure PPARG;SOD1;ATP1A1;PTGS2;PTGS1 GO:0042493| response to drug CAT;ATP1A1;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0034220| ion transmembrane transport TRPA1;GLRA1;TRPV1;GLRB;ATP1A1;GLRA3;CHRNA7 GO:0086002| ATP1A1;CACNA1G 18744:[DB14011 DB05478] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05478|Pradefovir Mesylate CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1 GO:0055114| oxidation-reduction process CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 18745:[DB14011 DB00456] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;ALB;GSR GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0006810| transport ABCC1;SLC15A1;CACNA1I;TRPV1;ABCG2;SLC15A2;TRPV2 GO:0055085| transmembrane transport SLC22A8;SLC15A2;SLC22A5;TRPV3;CACNA1H;SLC22A11;SLC22A7;TRPV2;SLC15A1;TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;CACNA1I;TRPV4;VDAC1 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0098656| SLC22A8;SLC22A7;SLC22A6;VDAC1 GO:0006811| ion transport CACNA1G;SLC15A1;TRPA1;GLRA1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;CACNA1H;TRPV3;SLC15A2;SLC22A5;GLRA3;SLC22A8;TRPV2;SLC22A7;CHRNA7;SLC22A11 GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A5 GO:0001895| retina homeostasis ALB;SOD1 18746:[DB14011 DB03214] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;IL4I1;CRYZ;CYP1A1;CYP2C9 18747:[DB14011 DB06987] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PLA2G2E;CNR2;PTGS2;ALOX5;PTGS1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;LTF GO:0036148| PLA2G1B;PLA2G2E GO:0001503| ossification ALOX15;LTF GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;PLA2G2E;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9 GO:0006351| transcription, DNA-dependent PPARG;LTF GO:0036149| PLA2G2E;PLA2G1B GO:0061844| LTF;PLA2G1B GO:0036150| PLA2G1B;PLA2G2E GO:0001895| retina homeostasis LTF;SOD1 GO:0006811| ion transport TRPV2;LTF;CHRNA7;TRPV3;CACNA1H;GLRA3;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0002227| innate immune response in mucosa PLA2G1B;LTF GO:0050482| arachidonic acid secretion PLA2G2E;PLA2G1B GO:0019731| antibacterial humoral response PLA2G1B;LTF GO:0006355| regulation of transcription, DNA-dependent PPARG;LTF GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LTF GO:0045087| innate immune response PPARG;LTF GO:0043312| neutrophil degranulation CAT;LTF;ALOX5 GO:0006654| phosphatidic acid biosynthetic process PLA2G2E;PLA2G1B GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;LTF GO:0036151| PLA2G1B;PLA2G2E GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;PLA2G2E GO:0016042| lipid catabolic process PLA2G2E;PLA2G1B;DAGLA;NAPEPLD GO:0036152| PLA2G2E;PLA2G1B GO:0002376| immune system process LTF;IDO1 18748:[DB14011 DB11623] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11623|Candoxatrilat MME common genes common pathways GO:0071345| cellular response to cytokine stimulus MME;TRPV1 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;MME;TRPA1;TRPV1 GO:0001822| kidney development CAT;MME GO:0043312| neutrophil degranulation MME;CAT;ALOX5 18749:[DB14011 DB02299] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02299|Arginineamide KCNA4 common genes common pathways GO:0006811| ion transport GLRA3;KCNA4;TRPV3;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;KCNA4 GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;KCNA4 GO:0051260| protein homooligomerization KCNA4;GLRA3;ACAT1;GLRA1 18750:[DB14011 DB03062] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03062|(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone NMT1;NMT1 common genes common pathways 18751:[DB14011 DB08799] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08799|Antazoline HRH1 common genes common pathways GO:0008542| visual learning HRH1;HMGCR GO:0006954| inflammatory response HRH1;PTGS2;CNR2;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;HRH1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7 GO:0045907| positive regulation of vasoconstriction HTR2A;HRH1;PTGS2 GO:0007613| memory CHRNA7;HRH1;PTGS2;CNR1;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;HRH1;OPRM1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;HRH1 18752:[DB14011 DB03934] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways GO:0045333| cellular respiration CYP1A2;CYCS GO:0006915| apoptotic process GPX1;CYCS;VDAC1 GO:0034599| cellular response to oxidative stress GSR;CYCS;SOD1;GPX1;CAT GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYCS;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1 18753:[DB14011 DB06081] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06081|Caplacizumab VWF common genes common pathways GO:0009611| response to wounding CYP1A1;VWF;GPX1 GO:0051260| protein homooligomerization VWF;GLRA3;ACAT1;GLRA1 GO:0007155| cell adhesion VWF;CYP1B1 GO:0002576| platelet degranulation VWF;SOD1 18754:[DB14011 DB12637] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADGRD1;PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;TRPV4;TRPV1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;ADGRD1;PLA2G1B;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;NR3C1;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway ADGRD1;TRPV1;TRPA1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 18755:[DB14011 DB07000] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways GO:0048538| thymus development BRAF;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;BRAF;TRPV4;ALOX15 GO:0051591| response to cAMP BRAF;AANAT GO:0015758| glucose transport PLA2G1B;BRAF GO:0010628| positive regulation of gene expression TRPV4;BRAF GO:0042127| regulation of cell proliferation PTGS2;PTGS1;BRAF GO:0043066| negative regulation of apoptotic process BRAF;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0043434| response to peptide hormone stimulus BRAF;TRPV1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CACNA1I;BRAF;PLA2G1B;SMPD1;GPR18;PPARG GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;BRAF GO:0051291| protein heterooligomerization BRAF;GLRB;GLRA1 GO:0071277| cellular response to calcium ion ALOX15;BRAF GO:1990090| TRPV1;BRAF GO:0035556| intracellular signal transduction PLA2G1B;BRAF GO:0043524| negative regulation of neuron apoptosis SOD1;BRAF GO:0008542| visual learning BRAF;HMGCR 18756:[DB14011 DB07070] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;PPARD;CYP1A2;PTGS2;GPX1;NAAA;PTGS1 GO:0007507| heart development PPARG;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0006351| transcription, DNA-dependent PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARD GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0001890| placenta development PPARD;SOD1;PPARG GO:0060612| adipose tissue development ACAT1;PPARD GO:0019395| fatty acid oxidation PPARG;PPARD GO:0045600| positive regulation of fat cell differentiation PPARD;HTR2A;PPARG GO:0014823| response to activity CAT;PPARD GO:0008283| cell proliferation HTR1A;PPARD;GPX1;CYP1A1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0007566| embryo implantation PTGS2;PPARD;SOD1 GO:0050728| negative regulation of inflammatory response PPARD;CNR2 GO:0033189| response to vitamin A PPARD;CAT;CYP1A1;PPARG GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARG GO:0043066| negative regulation of apoptotic process SOD1;PPARD;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;PPARD;HMGCR;PTGS2;HTR2A;HTR1A GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PPARD GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0042060| wound healing ALOX15;PPARD;OPRM1 GO:0042127| regulation of cell proliferation PTGS1;PPARD;PTGS2 GO:0008203| cholesterol metabolic process HMGCR;PPARD;CAT GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG GO:0015758| glucose transport PPARD;PLA2G1B GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARD;PPARG;CYP1A1;TRPA1 GO:0006915| apoptotic process VDAC1;PPARD;GPX1 GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0046697| decidualization PTGS2;PPARD GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;PPARD;OPRD1 18757:[DB14011 DB05447] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05447|AVI-4557 HNF4A common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;HNF4A GO:0045893| positive regulation of transcription, DNA-dependent PPARG;HNF4A GO:0006355| regulation of transcription, DNA-dependent HNF4A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter HNF4A;PLA2G1B;PPARG GO:0030308| negative regulation of cell growth HNF4A;PPARG GO:0042593| glucose homeostasis CNR1;HNF4A;TRPV4;PPARG GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;HNF4A;CYP2C9 GO:0006629| lipid metabolic process HNF4A;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG;PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4 GO:0006357| regulation of transcription from RNA polymerase II promoter HNF4A;PPARG GO:0006351| transcription, DNA-dependent PPARG;HNF4A GO:0043401| steroid hormone mediated signaling pathway PPARG;HNF4A GO:0055088| lipid homeostasis HNF4A;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;HNF4A;OPRM1;PTGS2 GO:0007548| sex differentiation CYP17A1;HNF4A GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HNF4A;HMGCR;CNR1 GO:0050796| regulation of insulin secretion CNR1;HNF4A 18758:[DB14011 DB07485] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07485|4,4'-cyclohexane-1,1-diyldiphenol ESRRG common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESRRG;PPARG GO:0006351| transcription, DNA-dependent PPARG;ESRRG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESRRG GO:0006355| regulation of transcription, DNA-dependent PPARG;ESRRG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESRRG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;PLA2G1B;PPARG 18759:[DB14011 DB09298] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09298|Silibinin A UGT1A1;SLC22A6;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0007584| response to nutrient HMGCR;CNR1;UGT1A1;PPARG GO:0098656| SLC22A6;VDAC1 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;SLCO2B1;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;SLCO1B1;GLRA3;SLCO1B3;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;UGT1A1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0008152| metabolic process ACAT1;UGT1A1;SMPD1 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;UGT1A1;CYP3A4;CYP1A2 GO:0045471| response to ethanol CNR1;SOD1;OPRM1;HMGCR;CAT;UGT1A1 GO:0001889| liver development ACAT1;UGT1A1;CYP1A1 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;UGT1A1;CYP1A1;CYP2C9;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0010033| response to organic substance UGT1A1;TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 GO:0055085| transmembrane transport TRPV2;SLCO1B1;SLCO1B3;TRPV3;CACNA1H;SLCO2B1;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G;SLC22A6 GO:0042594| response to starvation UGT1A1;PPARG;ACAT1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CYP1A1;UGT1A1;IDO1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0042493| response to drug UGT1A1;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT 18760:[DB14011 DB00982] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00982|Isotretinoin RARA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RARA GO:0006355| regulation of transcription, DNA-dependent RARA;PPARG GO:0033189| response to vitamin A RARA;CAT;CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARA;PPARG GO:0032526| response to retinoic acid PPARG;RARA GO:0043066| negative regulation of apoptotic process RARA;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0071300| cellular response to retinoic acid RARA;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;RARA;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARA;TRPV1;TRPV4;PPARG GO:0034097| response to cytokine stimulus AANAT;RARA;PTGS2 GO:0007283| spermatogenesis RARA;CNR1;SOD1 GO:0043277| apoptotic cell clearance RARA;ALOX15 GO:0010628| positive regulation of gene expression RARA;TRPV4 GO:0001657| ureteric bud development CAT;RARA GO:0045892| negative regulation of transcription, DNA-dependent PPARG;RARA GO:0032355| response to estradiol stimulus RARA;CAT;CYP1A2;PTGS2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;RARA;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;RARA GO:0007565| female pregnancy RARA;IDO1 GO:0006351| transcription, DNA-dependent RARA;PPARG GO:0001889| liver development ACAT1;RARA;CYP1A1 GO:0043401| steroid hormone mediated signaling pathway RARA;PPARG GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;RARA;CAT GO:0008285| negative regulation of cell proliferation RARA;PTGS2;OPRM1;CYP1B1;PPARG GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;RARA;CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A 18761:[DB14011 DB05107] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;G6PD;GSR GO:0006695| cholesterol biosynthetic process G6PD;HMGCR GO:0043523| regulation of neuron apoptosis G6PD;GPX1 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;G6PD;CYP2C9;CYP1A1;CRYZ GO:0032094| response to food OPRM1;G6PD;CYP1A1 GO:0010041| response to iron(III) ion G6PD;CYP1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;G6PD;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;G6PD GO:0006749| glutathione metabolic process GSR;G6PD;SOD1;GPX1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;G6PD GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1;G6PD 18762:[DB14011 DB01990] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01990|Cholesterol sulfate RORA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RORA GO:0006355| regulation of transcription, DNA-dependent PPARG;RORA GO:0050728| negative regulation of inflammatory response CNR2;RORA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RORA GO:0007623| circadian rhythm AANAT;RORA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RORA;PPARG;PLA2G1B GO:0048511| rhythmic process AANAT;RORA;PPARG GO:0071356| cellular response to tumor necrosis factor TRPV1;RORA GO:0060850| regulation of transcription involved in cell fate commitment PPARG;RORA GO:0071456| cellular response to hypoxia RORA;OPRD1;PTGS2;SLC29A1 GO:0042752| regulation of circadian rhythm PPARG;RORA GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;RORA;PTGS2 GO:0043401| steroid hormone mediated signaling pathway RORA;PPARG GO:0006351| transcription, DNA-dependent RORA;PPARG GO:0001525| angiogenesis PTGS2;RORA;CYP1B1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;RORA;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006809| nitric oxide biosynthetic process RORA;CYP1B1 18763:[DB14011 DB03682] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;TTR GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0042572| retinol metabolic process CYP1B1;TTR 18764:[DB14011 DB02868] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways GO:0055085| transmembrane transport VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CALM1;CACNA1H;TRPV3 GO:0007186| G-protein coupled receptor signaling pathway CALM1;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;GPR18;PPARG GO:0006936| muscle contraction CALM1;CACNA1H;GLRA1 GO:0002576| platelet degranulation SOD1;CALM1 GO:0035307| positive regulation of protein dephosphorylation SMPD1;CALM1 GO:0051592| response to calcium ion CALM1;AANAT GO:0002027| regulation of heart rate CALM1;CACNA1G 18765:[DB14011 DB01328] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01328|Cefonicid mrcA;ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0098869| GSR;ALB;CAT;PTGS1;GPX1;PTGS2 18766:[DB14011 DB08789] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08789|2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;HSP90AA1;SMPD1 GO:0009409| response to cold TRPM8;PPARG;HSP90AA1;TRPA1 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;OPRM1;PTGS2 GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AA1 18767:[DB14011 DB13178] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13178|Inositol SLC5A3 common genes common pathways GO:0043576| regulation of respiratory gaseous exchange SLC5A3;GLRA1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;SLC5A3;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0006810| transport ABCC1;TRPV1;CACNA1I;SLC5A3;ABCG2;TRPV2 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;SLC5A3;TRPM8;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1 18768:[DB14011 DB12670] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12670|Rolofylline ADORA1 common genes common pathways GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;IDO1;ALOX15;TRPV1;ADORA1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;ADORA1;HTR2A GO:0045776| negative regulation of blood pressure CNR1;ADORA1 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1;ADORA1 GO:0007399| nervous system development GLRB;ADORA1;SMPD1 GO:0032229| negative regulation of synaptic transmission, GABAergic CNR2;ADORA1 GO:0051930| regulation of sensory perception of pain ADORA1;OPRM1;OPRD1 GO:0045777| positive regulation of blood pressure ADORA1;CNR1 GO:0008285| negative regulation of cell proliferation CYP1B1;ADORA1;PPARG;PTGS2;OPRM1 GO:0050890| cognition CHRNA7;ADORA1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADORA1 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;ADORA1;PPARG;CACNA1I;PLA2G1B GO:0060087| relaxation of vascular smooth muscle ADORA1;SOD1 GO:0050728| negative regulation of inflammatory response ADORA1;CNR2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;ADORA1 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;GLRA1;ADORA1;CHRNA7;SLC29A1;GLRA3;OPRM1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ADORA1 GO:0035307| positive regulation of protein dephosphorylation ADORA1;SMPD1 GO:0016042| lipid catabolic process ADORA1;PLA2G1B;DAGLA;NAPEPLD GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;ADORA1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADORA1;GPR18;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0097756| ADORA1;PTGS2;HMGCR 18769:[DB14011 DB03591] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03591|RU82209 SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;SRC;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0016236| macroautophagy SRC;VDAC1 GO:0045087| innate immune response PPARG;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0043066| negative regulation of apoptotic process SRC;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;SRC GO:0009615| response to virus SRC;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1 GO:0002376| immune system process IDO1;SRC GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0031667| response to nutrient levels SRC;SOD1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0043065| positive regulation of apoptotic process SRC;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;SRC;TRPA1 GO:0008283| cell proliferation CYP1A1;HTR1A;SRC;GPX1 GO:0070542| response to fatty acid PTGS2;CAT;SRC GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;SRC;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0045453| bone resorption GPR55;SRC GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG 18770:[DB14011 DB05243] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05243|XL019 JAK2 common genes common pathways GO:0046677| response to antibiotic JAK2;CYP1A1;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;JAK2 GO:0035722| interleukin-12-mediated signaling pathway JAK2;SOD1 GO:0045087| innate immune response JAK2;PPARG GO:0042127| regulation of cell proliferation JAK2;PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;JAK2;CYP1A1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0033194| response to hydroperoxide JAK2;GPX1 GO:0002376| immune system process JAK2;IDO1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;JAK2 GO:0043388| positive regulation of DNA binding PPARG;JAK2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;JAK2 GO:0007186| G-protein coupled receptor signaling pathway JAK2;PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;JAK2 GO:0034612| response to tumor necrosis factor JAK2;PTGS2 GO:0006915| apoptotic process GPX1;JAK2;VDAC1 GO:0050727| regulation of inflammatory response PTGS2;JAK2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;JAK2;PPARG GO:0035556| intracellular signal transduction PLA2G1B;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation JAK2;HTR2A GO:0043524| negative regulation of neuron apoptosis JAK2;SOD1 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1;JAK2 GO:0010811| positive regulation of cell-substrate adhesion JAK2;ALOX15 GO:0007165| signal transduction SMPD1;JAK2;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7 GO:0050729| positive regulation of inflammatory response TRPV4;JAK2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;JAK2;OPRM1;HTR2A GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;JAK2;PPARG;CYP1B1 GO:0006919| activation of caspase activity JAK2;PPARG 18771:[DB14011 DB11692] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11692|Pavinetant TACR3 common genes common pathways GO:0043278| response to morphine TACR3;OPRM1;CNR1 GO:0042538| hyperosmotic salinity response TRPV4;TACR3 GO:0042220| response to cocaine SMPD1;OPRM1;CNR1;TACR3 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;TACR3 GO:0032355| response to estradiol stimulus TACR3;CAT;CYP1A2;PTGS2 GO:0007568| aging CYP1A1;CAT;TACR3;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR GO:0060259| regulation of feeding behavior TACR3;CNR1 GO:0042053| regulation of dopamine metabolic process HTR1A;TACR3 GO:0045777| positive regulation of blood pressure TACR3;CNR1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;TACR3;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 18772:[DB14011 DB07157] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways 18773:[DB14011 DB01404] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01404|Ginseng IL6;PTGS2;AHR common genes PTGS2 common pathways GO:0051384| response to glucocorticoid stimulus IL6;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;IL6 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin GPX1;CAT;AHR;CYP1A1;CYP1B1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0070301| cellular response to hydrogen peroxide IL6;CYP1B1 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;IL6;OPRM1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:0006351| transcription, DNA-dependent PPARG;AHR GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IL6;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;AHR;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;TRPV1;IL6;ALOX15;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IL6;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;PPARG GO:0006955| immune response IL6;OPRD1;CNR2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0002446| neutrophil mediated immunity IL6;PLA2G1B GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0010468| regulation of gene expression CYP1A2;AHR GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR GO:0032966| negative regulation of collagen biosynthetic process IL6;PPARG GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0006915| apoptotic process VDAC1;AHR;GPX1 GO:0010628| positive regulation of gene expression TRPV4;IL6 GO:0048511| rhythmic process AHR;PPARG;AANAT GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;AHR GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;CYP1A1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0009410| response to xenobiotic stimulus GPX1;AHR GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;PLA2G1B;PPARG;AHR GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process IL6;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0006355| regulation of transcription, DNA-dependent AHR;PPARG GO:0050830| defense response to Gram-positive bacterium PLA2G1B;IL6 GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AHR;PPARG;IL6 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0046427| positive regulation of JAK-STAT cascade IL6;CYP1B1 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation IL6;PTGS2;HMGCR GO:0009750| response to fructose stimulus PTGS2 18774:[DB14011 DB08006] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy DHODH;IDO1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;DHODH;SOD1;CNR1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;DHODH;TRPA1;PPARG;CYP1A1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;DHODH;HTR2A;SOD1;PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ;ALOX5;PTGS1;GPX1;CAT;DHODH;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0031000| response to caffeine DHODH;PPARG 18775:[DB14011 DB06735] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06735|Enclomiphene CYP2D6 common genes CYP2D6 common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process ALOX15;DAGLA;CYP2D6;CYP1B1;FAAH GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;NAAA;GPX1;PTGS1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0051100| negative regulation of binding CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 18776:[DB14011 DB03769] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03769|D-Eritadenine AHCY common genes common pathways GO:0007584| response to nutrient HMGCR;CNR1;AHCY;PPARG GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;AHCY GO:0032259| methylation CYP1A2;AHCY 18777:[DB14011 DB04682] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 18778:[DB14011 DB07787] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07787|5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE PARP1 common genes common pathways GO:0071294| cellular response to zinc ion PARP1;GLRA1 GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0032869| cellular response to insulin stimulus PARP1;PPARG;PLA2G1B GO:0010332| response to gamma radiation GPX1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;PARP1;GSR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;PPARG;TRPV1;TRPV4 GO:0006915| apoptotic process VDAC1;GPX1;PARP1 18779:[DB14011 DB02426] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02426|Carboxyatractyloside SLC25A4 common genes common pathways GO:0016032| viral reproduction HTR2A;VDAC1;SLC25A4 GO:0050796| regulation of insulin secretion SLC25A4;CNR1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;CACNA1G;SLC25A4;ABCC1 GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCG2;SLC25A4;ABCC1 18780:[DB14011 DB06997] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;MET GO:0008283| cell proliferation GPX1;MET;HTR1A;CYP1A1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;MET;OPRM1;CNR2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;MET 18781:[DB14011 DB07966] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07966|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile SRC common genes common pathways GO:0042493| response to drug CAT;SRC;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1 GO:0016236| macroautophagy SRC;VDAC1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response PPARG;SRC GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;SRC;ALOX15;TRPV4 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process IDO1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SRC;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042542| response to hydrogen peroxide CAT;GPX1;SRC;SOD1;TRPA1 GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0008283| cell proliferation CYP1A1;HTR1A;SRC;GPX1 GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0007165| signal transduction CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;SRC;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0070542| response to fatty acid PTGS2;CAT;SRC GO:0045453| bone resorption SRC;GPR55 18782:[DB14011 DB05464] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways GO:0007568| aging CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;NFKB2;CYP1A1 GO:0071356| cellular response to tumor necrosis factor TRPV1;NFKB1 GO:0048511| rhythmic process AANAT;NFKB2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NFKB1 GO:0006915| apoptotic process VDAC1;NFKB1;GPX1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;NFKB2;PPARG;TRPV1;TRPV4 GO:0045087| innate immune response NFKB1;PPARG;NFKB2 GO:0034097| response to cytokine stimulus PTGS2;AANAT;NFKB2 GO:0043312| neutrophil degranulation NFKB1;CAT;ALOX5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB2;PPARG;PLA2G1B;NFKB1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;NFKB1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;CYP1A1;NFKB2;IDO1 GO:0050728| negative regulation of inflammatory response NFKB1;CNR2 GO:0006355| regulation of transcription, DNA-dependent NFKB1;PPARG;NFKB2 GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;PPARG GO:0007165| signal transduction PPARG;NFKB2;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;NFKB1;CHRNA7 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0006351| transcription, DNA-dependent NFKB1;PPARG;NFKB2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NFKB1 GO:0006954| inflammatory response NFKB1;ALOX5;PTGS1;CNR2;PTGS2;ALOX15;IDO1;TRPV1;NFKB2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;NFKB1;PLA2G1B;NFKB2 GO:0010629| negative regulation of gene expression OPRD1;NFKB1 18783:[DB14011 DB04381] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;ALDH2;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0022900| electron transport chain IDO1;GSR;CYP1A2;ALDH2 GO:0008152| metabolic process SMPD1;ALDH2;ACAT1 18784:[DB14011 DB01644] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes GSR common pathways GO:0006749| glutathione metabolic process SOD1;GPX1;GSR GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0045454| cell redox homeostasis GSR;GPX1 GO:0098869| GSR;PTGS2;GPX1;PTGS1;CAT GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0034599| cellular response to oxidative stress GPX1;CAT;SOD1;GSR 18785:[DB14011 DB03991] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;PTGS2;CYP1A2;NEU2;HMGCR;NAAA;GPX1;PTGS1;PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0008152| metabolic process ACAT1;NEU2;SMPD1 GO:0006687| glycosphingolipid metabolic process SMPD1;NEU2 GO:0016042| lipid catabolic process PLA2G1B;DAGLA;NEU2;NAPEPLD 18786:[DB14011 DB08350] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide CYP1B1;ABL1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;ABL1;TRPV1;TRPV4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;HTR2A GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;ABL1;SMPD1;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;ABL1;TRPV4 GO:0006915| apoptotic process ABL1;VDAC1;GPX1 GO:0048538| thymus development SOD1;ABL1 GO:0006979| response to oxidative stress ABL1;PTGS2;SOD1;PTGS1;GPX1;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;GSR;ABL1 GO:0043542| endothelial cell migration ABL1;CYP1B1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;ABL1 GO:0007155| cell adhesion ABL1;CYP1B1 GO:0045087| innate immune response ABL1;PPARG 18787:[DB14011 DB08743] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001666| response to hypoxia DPP4;CYP1A1;CHRNA7;CAT GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043542| endothelial cell migration CYP1B1;DPP4 18788:[DB14011 DB05200] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05200|AT2220 GAA common genes common pathways GO:0008152| metabolic process SMPD1;GAA;ACAT1 GO:0046716| muscle cell homeostasis GAA;SOD1 GO:0007626| locomotory behavior SOD1;GAA;OPRM1 GO:0043312| neutrophil degranulation CAT;ALOX5;GAA GO:0050884| neuromuscular process controlling posture GLRA1;GAA 18789:[DB14011 DB02875] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02875|CRA_1802 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18790:[DB14011 DB14707] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14707|Cemiplimab PDCD1 common genes common pathways GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;PDCD1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;PDCD1;CNR1;SOD1 GO:0002376| immune system process PDCD1;IDO1 GO:0006915| apoptotic process PDCD1;GPX1;VDAC1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PDCD1;PTGS2;HMGCR;SOD1 GO:0070234| positive regulation of T cell apoptosis IDO1;PDCD1 18791:[DB14011 DB12960] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12960|INCB-9471 CCR5 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;CCR5;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;CCR5;ALOX5;PTGS1;CNR2;PTGS2 GO:0006955| immune response CCR5;OPRD1;CNR2 GO:0006816| calcium ion transport CACNA1G;CCR5;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1H;TRPV3;TRPV2;CHRNA7 GO:0016032| viral reproduction HTR2A;VDAC1;CCR5 GO:0007166| cell surface receptor linked signaling pathway CCR5;TRPA1;TRPV1 GO:0007165| signal transduction CACNA1I;PLA2G1B;CCR5;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;CCR5;TRPV4;TRPV1 18792:[DB14011 DB09333] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09333|Iopodic acid DIO3;ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0098869| GPX1;PTGS1;CAT;PTGS2;ALB;GSR GO:0042446| hormone biosynthetic process DIO3;CYP17A1 GO:0006915| apoptotic process DIO3;VDAC1;GPX1 GO:0043066| negative regulation of apoptotic process ALB;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0002576| platelet degranulation ALB;SOD1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;DIO3;CRYZ;CYP2C9;CYP1A1;ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 18793:[DB14011 DB11571] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11571|Human Thrombin F5;F8;F11;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0002376| immune system process FGB;IDO1;FGA GO:0070374| positive regulation of ERK1 and ERK2 cascade FGB;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;FGA;ALOX15;FGG GO:0050714| positive regulation of protein secretion FGG;FGA;PLA2G1B;FGB GO:0045087| innate immune response PPARG;FGA;FGB GO:0002576| platelet degranulation F13A1;FGA;F5;F8;FGG;FGB;SOD1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;F8;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALOX5;GPX1;PTGS1 GO:0034116| positive regulation of heterotypic cell-cell adhesion FGB;FGA;ALOX15;FGG GO:0007165| signal transduction FGA;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;FGG;CHRNA7;FGB;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0045907| positive regulation of vasoconstriction FGG;FGA;HTR2A;PTGS2;FGB GO:1902042| FGG;FGA;GPX1;FGB GO:0051592| response to calcium ion FGG;FGA;FGB;AANAT 18794:[DB14011 DB00293] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0009636| response to toxin CYP1B1;TYMS;CYP1A1;CAT;GPX1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TYMS;TRPA1 GO:0008283| cell proliferation CYP1A1;FPGS;GPX1;HTR1A GO:0006139| nucleobase-containing compound metabolic process SLC29A1;FPGS GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR GO:0007420| brain development FPGS;ACAT1 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0001889| liver development CYP1A1;ACAT1;FPGS GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;TYMS GO:0031100| organ regeneration PPARG;FPGS GO:0007568| aging HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CAT;CYP1A1;TYMS GO:0033189| response to vitamin A CAT;CYP1A1;TYMS;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;TYMS;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0032259| methylation TYMS;CYP1A2 GO:0034097| response to cytokine stimulus PTGS2;AANAT;TYMS GO:0007623| circadian rhythm AANAT;TYMS 18795:[DB14011 DB07602] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;EGFR GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;CAT;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;EGFR;TRPV1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1;EGFR GO:0033993| response to lipid PPARG;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;EGFR GO:0043406| positive regulation of MAP kinase activity HTR2A;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EGFR GO:0030324| lung development EGFR;CYP1A2 GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;EGFR GO:0042060| wound healing OPRM1;ALOX15;EGFR GO:0007623| circadian rhythm EGFR;AANAT GO:0007611| learning or memory CHRNA7;CNR1;EGFR GO:0008284| positive regulation of cell proliferation EGFR;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process EGFR;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;EGFR GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2;OPRD1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;EGFR;CACNA1I;PLA2G1B;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;EGFR GO:0008283| cell proliferation GPX1;HTR1A;EGFR;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;EGFR;PTGS2;CYP1A2;ACAT1;AANAT GO:0032930| positive regulation of superoxide anion generation SOD1;EGFR GO:0071276| cellular response to cadmium ion EGFR;CYP1A2;SOD1 GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0007166| cell surface receptor linked signaling pathway TRPV1;EGFR;TRPA1 GO:0051592| response to calcium ion EGFR;AANAT GO:0001889| liver development ACAT1;CYP1A1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0001503| ossification ALOX15;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;EGFR GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7 18796:[DB14011 DB04215] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04215|CRA_9076 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18797:[DB14011 DB12615] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12615|Plazomicin rpsN;rpsK;SLC47A1;SLC47A2 common genes common pathways GO:0006855| drug transmembrane transport SLC47A1;SLC47A2;ABCG2;ABCC1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2;SLC47A1;SLC47A2 18798:[DB14011 DB08818] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08818|Hyaluronic acid CD44;ICAM1;HMMR;NCAN;VCAN;C1QBP;HAPLN1;HAPLN3;HAPLN4;HABP2;LAYN;STAB2;TNFAIP6;IMPG2;HABP4 common genes common pathways GO:0002576| platelet degranulation HABP4;SOD1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;CD44;HMGCR;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;C1QBP;TRPV4;TRPV1 GO:0007155| cell adhesion CYP1B1;TNFAIP6;ICAM1;VCAN;NCAN;CD44;HAPLN4;HAPLN1;HABP2;STAB2;HAPLN3 GO:0045087| innate immune response PPARG;C1QBP GO:0043312| neutrophil degranulation CD44;ALOX5;CAT;TNFAIP6 GO:0032496| response to lipopolysaccharide CYP1A1;ICAM1;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0030838| positive regulation of actin filament polymerization ICAM1;ALOX15 GO:0071333| cellular response to glucose stimulus SLC29A1;ICAM1 GO:0050728| negative regulation of inflammatory response TNFAIP6;CNR2 GO:0051897| positive regulation of protein kinase B signaling cascade C1QBP;GPX1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;ICAM1;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;STAB2 GO:0006355| regulation of transcription, DNA-dependent PPARG;HABP4;C1QBP GO:0051926| negative regulation of calcium ion transport ICAM1;PTGS2 GO:0055114| oxidation-reduction process HMGCR;STAB2;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 GO:0007569| cell aging SOD1;ICAM1 GO:0002376| immune system process C1QBP;IDO1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ICAM1;OPRM1;PTGS2 GO:0007605| sensory perception of sound SOD1;GPX1;ICAM1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1;ICAM1 GO:0001666| response to hypoxia CHRNA7;CAT;ICAM1;CYP1A1 GO:0046688| response to copper ion ICAM1;AANAT;SOD1 GO:0071356| cellular response to tumor necrosis factor ICAM1;TRPV1 GO:0043200| response to amino acid stimulus GLRA3;GLRB;ICAM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CD44;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ICAM1;ALOX15;TRPV4 GO:0006915| apoptotic process GPX1;VDAC1;C1QBP GO:0001541| ovarian follicle development SOD1;ICAM1 GO:0071312| cellular response to alkaloid ICAM1;TRPV1 GO:0043065| positive regulation of apoptotic process SMPD1;C1QBP;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0030728| ovulation PTGS2;TNFAIP6 GO:0071260| cellular response to mechanical stimulus HABP4;PTGS2 GO:0001525| angiogenesis PTGS2;STAB2;CYP1B1 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;ICAM1 GO:0006351| transcription, DNA-dependent C1QBP;PPARG;HABP4 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;ICAM1;PLA2G1B GO:0006954| inflammatory response IDO1;ALOX15;TNFAIP6;TRPV1;ALOX5;PTGS1;CNR2;PTGS2 GO:0016032| viral reproduction HTR2A;VDAC1;C1QBP;ICAM1 GO:0006955| immune response C1QBP;CNR2;OPRD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD44;ICAM1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CD44;PTGS2 GO:0014065| phosphatidylinositol 3-kinase cascade C1QBP;HTR2A GO:0045907| positive regulation of vasoconstriction ICAM1;PTGS2;HTR2A GO:0034116| positive regulation of heterotypic cell-cell adhesion CD44;ALOX15 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;CD44 GO:0007165| signal transduction SMPD1;GPR18;PPARG;TNFAIP6;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7 GO:0046718| entry of virus into host cell ICAM1;HTR2A GO:0001975| response to amphetamine CNR2;SOD1;ICAM1 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB;IMPG2 GO:0001649| osteoblast differentiation VCAN;CAT GO:1902042| ICAM1;GPX1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;ICAM1;TRPA1;CYP1A1;PPARG GO:0002438| acute inflammatory response to antigenic stimulus ICAM1;OPRM1 GO:0032868| response to insulin stimulus AANAT;CAT;TRPV4;ICAM1 18799:[DB14011 DB07609] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1 GO:0009804| coumarin metabolic process CYP2A6;CYP1A1;CYP2D6 GO:0055114| oxidation-reduction process CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP2A6;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP2A6;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP2A6;CYP3A4 18800:[DB14011 DB03323] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03323|Maltose AMY2B;aglA common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;AMY2B 18801:[DB14011 DB04617] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0008283| cell proliferation GPX1;ACHE;HTR1A;CYP1A1 GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development CACNA1H;ACHE GO:0009611| response to wounding CYP1A1;ACHE;GPX1 GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B 18802:[DB14011 DB01213] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes CAT common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1;PTGS1 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;TRPA1 GO:0045471| response to ethanol CAT;SOD1;CNR1;CYP2E1;HMGCR;OPRM1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B GO:0051289| protein homotetramerization CAT;CRYZ;TRPA1;TRPV1;TRPM8 GO:0042738| exogenous drug catabolic process CYP3A4;CYP2A6;CYP1A2;CYP2C9;CYP2C19 GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:0070542| response to fatty acid CAT;PTGS2 GO:0001649| osteoblast differentiation CAT GO:0014823| response to activity CAT GO:0009650| UV protection GPX1;CAT GO:0051781| positive regulation of cell division CAT GO:0032868| response to insulin stimulus AANAT;CAT;TRPV4 GO:0014854| response to inactivity CAT GO:0033591| response to L-ascorbic acid CAT GO:0009411| response to UV CAT GO:0009636| response to toxin CYP1A1;CYP1B1;CAT;GPX1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;CAT GO:0010288| response to lead ion CAT GO:0043312| neutrophil degranulation ALOX5;CAT GO:0020027| hemoglobin metabolic process CAT GO:0001822| kidney development CAT GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP2A6;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0034599| cellular response to oxidative stress GSR;SOD1;CAT;GPX1 GO:0033197| response to vitamin E CAT GO:0008203| cholesterol metabolic process HMGCR;CAT GO:0000302| response to reactive oxygen species GPX1;CAT;SOD1 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0009804| coumarin metabolic process CYP2A6;CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 GO:0009642| response to light intensity CAT GO:0055114| oxidation-reduction process SOD1;CYP2A6;CYP2E1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;ADH1C;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP1A1;CYP2C9;ADH1B;ADH1A;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0042493| response to drug CAT;CYP2E1;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0017144| drug metabolic process ADH1A;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1;CYP2A6 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0080184| response to phenylpropanoid CAT GO:0007568| aging CYP1A1;CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP2E1;CYP3A4;CYP2A6;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0009060| aerobic respiration CAT GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1 GO:0051262| protein tetramerization HMGCR;CAT GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0010193| response to ozone CAT;CYP2E1 GO:0001657| ureteric bud development CAT GO:0042744| hydrogen peroxide catabolic process CAT;GPX1 GO:0046686| response to cadmium ion CAT 18803:[DB14011 DB08021] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08021|5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide MAPK10 common genes common pathways GO:0009416| response to light stimulus AANAT;MAPK10 GO:0048511| rhythmic process MAPK10;PPARG;AANAT GO:0000187| activation of MAPK activity SOD1;CHRNA7;MAPK10;PLA2G1B GO:0010468| regulation of gene expression MAPK10;CYP1A2 GO:0042752| regulation of circadian rhythm MAPK10;PPARG GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;MAPK10 18804:[DB14011 DB00718] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0007399| nervous system development GLRB;SMPD1;NME1 GO:0006351| transcription, DNA-dependent NME2;PPARG GO:0001889| liver development CYP1A1;AK4;ACAT1 GO:0010976| positive regulation of neuron projection development NME1;CNR1 GO:0007595| lactation SLC29A1;NME1 GO:0010629| negative regulation of gene expression OPRD1;NME1 GO:0007420| brain development AK4;ACAT1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;NME1;PPARG;CYP1B1 GO:0098656| VDAC1;SLC22A6 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;SLC22A3;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G GO:0006139| nucleobase-containing compound metabolic process SLC29A1;AK4;AK2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;ACAT1;AANAT;ABCC4 GO:0006855| drug transmembrane transport SLC22A3;ABCG2;ABCC1 GO:0015949| nucleobase-containing small molecule interconversion NME2;GSR;AK2;AK4;NME1 GO:0002576| platelet degranulation SOD1;ABCC4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NME2;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process NME2;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0007155| cell adhesion NME2;CYP1B1 GO:0043312| neutrophil degranulation CAT;ALOX5;NME2 GO:0071333| cellular response to glucose stimulus SLC29A1;NME1 GO:0010243| response to organic nitrogen ABCC4;PTGS2;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;ABCC4 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;AK4;CAT;NME1;ABCC4;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent NME2;PPARG GO:0099133| ABCC4;ABCC1;ABCC5 GO:0055114| oxidation-reduction process ABCC4;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP2C9;CYP1A1 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0043388| positive regulation of DNA binding NME1;PPARG GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0006810| transport TRPV2;ABCC1;ABCC5;ABCG2;CACNA1I;TRPV1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;ABCC4;SOD1;PTGS2;CYP1A2 GO:0051591| response to cAMP AANAT;NME1 GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;ABCC5;TRPM8;CACNA1G;SLC22A6;ABCC1;TRPA1;TRPV2;ABCC4;CACNA1H;SLC22A3;TRPV3 18805:[DB14011 DB04463] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04463|3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol CBR1;CBR1 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CBR1;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0030855| epithelial cell differentiation CBR1;VDAC1;PPARG GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CBR1;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0019371| cyclooxygenase pathway PTGS2;PTGS1;CBR1 18806:[DB14011 DB04759] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04759|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13;ALOX15 18807:[DB14011 DB08238] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;GPX1 GO:0030324| lung development CYP1A2;FGF1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;FGF1;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;PLA2G1B;PPARG GO:0045766| positive regulation of angiogenesis FGF1;CHRNA7;CYP1B1 GO:0000187| activation of MAPK activity FGF1;SOD1;CHRNA7;PLA2G1B GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF1 GO:0034605| cellular response to heat PTGS2;FGF1;TRPV1;TRPV4 GO:0001934| positive regulation of protein phosphorylation CHRNA7;FGF1 GO:0001525| angiogenesis FGF1;PTGS2;CYP1B1 GO:0008283| cell proliferation CYP1A1;FGF1;HTR1A;GPX1 GO:0051781| positive regulation of cell division CAT;FGF1 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;FGF1;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 18808:[DB14011 DB03535] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03535|Z-Pro-Prolinal PREP common genes common pathways 18809:[DB14011 DB00151] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0006749| glutathione metabolic process GCLC;GPX1;SOD1;GSR;GCLM GO:0014823| response to activity GCLM;GCLC;CAT GO:0007584| response to nutrient GCLM;PPARG;CNR1;HMGCR;GCLC GO:0014070| response to organic cyclic compound AANAT;ACAT1;MGMT;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;MGMT GO:0009725| response to hormone stimulus ACAT1;GCLC GO:0045454| cell redox homeostasis GSR;GPX1;GCLC GO:0051384| response to glucocorticoid stimulus PTGS2;CDO1;GOT1 GO:0032869| cellular response to insulin stimulus GOT1;GCLC;PLA2G1B;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity CTH;CAT;PLA2G1B GO:0009408| response to heat TRPV1;TRPV3;SOD1;TRPV2;GCLC GO:0051289| protein homotetramerization TRPV1;TRPM8;TRPA1;CRYZ;CAT;CTH GO:0006954| inflammatory response PTGS2;CNR2;CDO1;ALOX5;PTGS1;ALOX15;IDO1;TRPV1 GO:0007595| lactation SLC29A1;CDO1 GO:0031667| response to nutrient levels GSS;SOD1 GO:0043524| negative regulation of neuron apoptosis GCLC;SOD1;GCLM GO:0008152| metabolic process ACAT1;CBS;SMPD1 GO:0071260| cellular response to mechanical stimulus GCLC;PTGS2 GO:0007399| nervous system development SMPD1;GLRB;GSS GO:0045471| response to ethanol SOD1;CNR1;MGMT;HMGCR;OPRM1;CDO1;CAT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;GCLC GO:0043200| response to amino acid stimulus GLRB;GSS;CDO1;GLRA3 GO:0051591| response to cAMP CDO1;AANAT GO:0046686| response to cadmium ion CAT;GCLC;GSS GO:0055085| transmembrane transport SLC16A10;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0034612| response to tumor necrosis factor PTGS2;GSS GO:0006979| response to oxidative stress GSS;GCLM;CAT;GCLC;PTGS1;GPX1;SOD1;PTGS2 GO:0007568| aging HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;GCLC;CAT;CYP1A1;GCLM;GSS GO:0010243| response to organic nitrogen TRPV1;PTGS2;CDO1 GO:0071407| cellular response to organic cyclic compound MGMT;CYP1B1;CYP1A1 GO:0042493| response to drug HTR2A;SOD1;MGMT;PTGS2;CYP1A2;CAT;TRPA1;GCLM;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2 GO:0046685| response to arsenic-containing substance GCLC;CYP1A1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;CDO1;PTGS2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CBS;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6 GO:0032259| methylation CYP1A2;MGMT GO:0043066| negative regulation of apoptotic process MGMT;SOD1;PTGS2;CTH;HMGCR;CAT;GCLC;GPX1 GO:0009410| response to xenobiotic stimulus GSS;GCLC;GPX1 GO:0071333| cellular response to glucose stimulus SLC29A1;GCLC;GCLM GO:0034599| cellular response to oxidative stress GSR;MGMT;SOD1;GPX1;CAT 18810:[DB14011 DB02751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02751|Glycocyamine GAMT common genes common pathways GO:0040014| regulation of multicellular organism growth GAMT;SOD1 GO:0007283| spermatogenesis CNR1;SOD1;GAMT GO:0006936| muscle contraction GLRA1;CACNA1H;GAMT GO:0032259| methylation GAMT;CYP1A2 18811:[DB14011 DB03185] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways GO:0030308| negative regulation of cell growth PPARG;CDA GO:0043312| neutrophil degranulation CDA;ALOX5;CAT GO:0051289| protein homotetramerization TRPM8;TRPV1;TRPA1;CRYZ;CAT;CDA GO:0007166| cell surface receptor linked signaling pathway CDA;TRPA1;TRPV1 18812:[DB14011 DB03453] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways GO:0002376| immune system process IL2;IDO1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;IL2;PPARG;GPR18 GO:0050728| negative regulation of inflammatory response IL2;CNR2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;IL2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;PLA2G1B;PPARG GO:0007155| cell adhesion CYP1B1;IL2 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0050729| positive regulation of inflammatory response TRPV4;IL2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;IL2;OPRM1;HTR2A GO:0006955| immune response IL2;CNR2;OPRD1 GO:0030217| T cell differentiation GPR18;IL2 GO:0001934| positive regulation of protein phosphorylation IL2;CHRNA7 GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;IL2 18813:[DB14011 DB09292] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09292|Sacubitril MME;SLCO1B1;SLCO1B3 common genes common pathways GO:0071345| cellular response to cytokine stimulus TRPV1;MME GO:0006811| ion transport TRPV3;CACNA1H;SLCO1B1;GLRA3;SLCO1B3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;CNR2;PTGS2;MME;OPRM1;HTR2A;CNR1 GO:0055085| transmembrane transport TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLCO1B3;SLCO1B1 GO:0043312| neutrophil degranulation CAT;ALOX5;MME GO:0001822| kidney development CAT;MME 18814:[DB14011 DB08024] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 18815:[DB14011 DB09038] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09038|Empagliflozin SLC5A2 common genes common pathways GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;VDAC1;TRPV4;GLRB;CACNA1I;SLC5A2;TRPV1;TRPM8;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV1;SLC5A2;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0006810| transport TRPV2;ABCC1;CACNA1I;TRPV1;SLC5A2;ABCG2 18816:[DB14011 DB07586] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways GO:0010629| negative regulation of gene expression HDAC8;OPRD1 GO:0006351| transcription, DNA-dependent HDAC8;PPARG GO:0006355| regulation of transcription, DNA-dependent HDAC8;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;PPARG;TRPV4;TRPV1 18817:[DB14011 DB04416] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04416|R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid MMP3 common genes common pathways 18818:[DB14011 DB06958] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06958|5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HSP90AA1;PTGS2;OPRM1 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0046677| response to antibiotic SOD1;CYP1A1;HSP90AA1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;HSP90AA1;PPARG;SMPD1 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0009409| response to cold HSP90AA1;PPARG;TRPA1;TRPM8 18819:[DB14011 DB07133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07133|D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide F2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;F2;PPARG;GPR18 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0061844| PLA2G1B;F2 18820:[DB14011 DB00074] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0042130| negative regulation of T cell proliferation IDO1;IL2RA GO:0006915| apoptotic process VDAC1;IL2RA;GPX1 GO:0002376| immune system process C1QA;IL2RA;C1QC;C1S;IDO1;FCGR1A;FCGR2A;C1R;C1QB GO:0050728| negative regulation of inflammatory response CNR2;IL2RA GO:0043066| negative regulation of apoptotic process IL2RB;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0043312| neutrophil degranulation FCGR3B;FCGR2A;CAT;ALOX5 GO:0045087| innate immune response C1QB;C1R;PPARG;FCGR1A;C1QC;C1S;C1QA GO:0046330| positive regulation of JNK cascade TRPV4;FCGR2B GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;IL2RA GO:0065009| regulation of molecular function IL2RA;IL2RB;TRPV1 GO:0007165| signal transduction IL2RB;SMPD1;GPR18;FCGR2B;PPARG;CACNA1I;PLA2G1B;FCGR1A;FCGR2C;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7 GO:0006955| immune response FCGR1A;C1R;FCGR2B;FCGR3B;CNR2;IL2RA;OPRD1;FCGR2C;FCGR3A;C1QC GO:0016032| viral reproduction FCGR2B;IL2RB;VDAC1;HTR2A GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;FCGR2B;PTGS1;ALOX5;PTGS2;CNR2;IL2RA GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;IL2RA 18821:[DB14011 DB02894] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02894|Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT 18822:[DB14011 DB03516] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0006919| activation of caspase activity XDH;PPARG GO:0007595| lactation SLC29A1;XDH GO:0006195| purine nucleotide catabolic process GPX1;XDH GO:0010629| negative regulation of gene expression OPRD1;XDH GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;AOX1;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CAT;DPYD;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;XDH;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;AOX1 GO:0022900| electron transport chain AOX1;GSR;IDO1;XDH;CYP1A2 18823:[DB14011 DB07330] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07330|trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium PARP1 common genes common pathways GO:0006915| apoptotic process VDAC1;PARP1;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PARP1 GO:0034599| cellular response to oxidative stress SOD1;PARP1;CAT;GPX1;GSR GO:0010332| response to gamma radiation PARP1;GPX1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PARP1 GO:0006351| transcription, DNA-dependent PARP1;PPARG GO:0071294| cellular response to zinc ion PARP1;GLRA1 18824:[DB14011 DB03128] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes CHRNA7 common pathways GO:1905144| CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;GLRB;TRPV1;GLRA1 GO:0007614| short-term memory CHRNA7 GO:1905906| CHRNA7 GO:0007611| learning or memory CNR1;CHRNA7 GO:0007155| cell adhesion CYP1B1;ACHE GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;CHRM1;HTR2A GO:0009615| response to virus CHRM2;CYP1A1 GO:0050808| synapse organization CHRNA7 GO:0007517| muscle organ development CACNA1H;ACHE GO:0050893| sensory processing CHRNA7 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0035094| response to nicotine CNR1;CHRNA7 GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0098815| CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;CHRM1;GPR12;CNR1;HTR2A;CHRM2;OPRM1;CNR2;OPRD1;CHRM4;PPARG;GPR18;CHRM3 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A1;GLRA1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CHRNA7;HTR2A;GPR12 GO:1901214| CHRNA7 GO:0055085| transmembrane transport SLC22A1;ABCC1;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;SLC22A5;TRPV2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;TRPV4 GO:1905920| CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0095500| CHRNA7 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;TRPV1;GLRB;GLRA1;TRPA1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;CNR1;OPRD1;CNR2;OPRM1 GO:1902991| CHRNA7 GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0140059| CHRNA7 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;CHRM4;TRPA1 GO:0008016| regulation of heart contraction CHRM2;CACNA1H GO:0007399| nervous system development CHRM2;CHRM1;ACHE;GLRB;SMPD1;CHRM3 GO:0060078| regulation of postsynaptic membrane potential CHRNA7 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CHRM2 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902430| CHRNA7 GO:0006816| calcium ion transport CACNA1H;TRPV3;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0050890| cognition CHRM1;CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;CHRM2;HTR1A;GPR55;CHRM1;CHRNA7;SMPD1;CHRM3;GPR18;PPARG;CHRM4;PLA2G1B;CACNA1I GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;TRPV3;OPRM1;CACNA1H;CHRNA7;TRPV2 GO:0006939| smooth muscle contraction HTR2A;CHRM3 GO:1900273| CHRNA7 GO:1904645| CHRNA7 GO:0006855| drug transmembrane transport ABCC1;SLC22A1;ABCG2;SLC22A5 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;SLC22A5;TRPV2;CHRNA7;CACNA1G;SLC22A1;TRPA1;GLRA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8 GO:0008283| cell proliferation ACHE;HTR1A;CHRM1;GPX1;CHRM3;CYP1A1;CHRM4 GO:0006812| cation transport TRPM8;SLC22A1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 18825:[DB14011 DB08888] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08888|Ocriplasmin FN1;A2M;SERPINF2 common genes common pathways GO:0007155| cell adhesion CYP1B1;FN1 GO:0002576| platelet degranulation SERPINF2;A2M;SOD1;FN1 GO:0008284| positive regulation of cell proliferation FN1;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINF2;PPARG;PLA2G1B GO:0030199| collagen fibril organization SERPINF2;CYP1B1 GO:0046330| positive regulation of JNK cascade SERPINF2;TRPV4 GO:0042060| wound healing OPRM1;FN1;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation SERPINF2;PTGS2;HMGCR GO:0051702| interaction with symbiont GPX1;FN1 GO:0071636| positive regulation of transforming growth factor beta production SERPINF2;PTGS2 GO:0048514| blood vessel morphogenesis CYP1B1;SERPINF2 GO:0009611| response to wounding FN1;CYP1A1;GPX1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SERPINF2;CYP1A2;PTGS2;SOD1 GO:0010628| positive regulation of gene expression FN1;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade SERPINF2;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55;TRPV4;ALOX15 GO:0001525| angiogenesis PTGS2;FN1;CYP1B1 GO:0045773| positive regulation of axon extension FN1;TRPV2 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;FN1 18826:[DB14011 DB03824] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03824|7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline PNMT common genes common pathways GO:0032259| methylation CYP1A2;PNMT 18827:[DB14011 DB01306] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01306|Insulin Aspart INSR common genes common pathways GO:0035556| intracellular signal transduction PLA2G1B;INSR GO:0045821| positive regulation of glycolysis HTR2A;INSR GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;INSR GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A;INSR GO:0045740| positive regulation of DNA replication INSR;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;INSR GO:0007612| learning PTGS2;VDAC1;INSR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0006355| regulation of transcription, DNA-dependent INSR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;INSR;CNR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;INSR;TRPV1 GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway INSR;GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0000187| activation of MAPK activity PLA2G1B;INSR;CHRNA7;SOD1 18828:[DB14011 DB02198] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02198|2-Bromoacetyl Group PTGS1 common genes PTGS1 common pathways GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A1;CYP2C9;CRYZ;ALOX5;PTGS1;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;ALOX5;PTGS1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 18829:[DB14011 DB00148] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0032259| methylation GAMT;CYP1A2 GO:0006936| muscle contraction GAMT;CACNA1H;CKMT2;SLC6A8;GLRA1 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;SLC6A8;TRPV2 GO:0007283| spermatogenesis GAMT;CNR1;SOD1 GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;SLC6A8;TRPV2;CACNA1H;TRPV3;SLC22A5 GO:0007420| brain development CKB;ACAT1 GO:0040014| regulation of multicellular organism growth SOD1;GAMT GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A5 GO:0006811| ion transport TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPA1;GLRA1;CACNA1G;CHRNA7;SLC6A8;TRPV2;SLC22A5;GLRA3;TRPV3;CACNA1H 18830:[DB14011 DB07780] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;KRAS;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0007601| visual perception RABGGTB;RABGGTA;GLRB;CYP1B1;GLRA1;CRYZ GO:0051384| response to glucocorticoid stimulus KRAS;PTGS2 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;NAAA;PTGS1;GPX1;FDPS;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0001889| liver development KRAS;ACAT1;CYP1A1 GO:0008542| visual learning KRAS;HMGCR GO:0016032| viral reproduction HTR2A;FDPS;VDAC1 GO:0051092| positive regulation of NF-kappaB transcription factor activity KRAS;CAT;PLA2G1B GO:0007565| female pregnancy KRAS;IDO1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KRAS GO:0043524| negative regulation of neuron apoptosis SOD1;KRAS GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1;FDPS;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0043406| positive regulation of MAP kinase activity KRAS;HTR2A GO:0010628| positive regulation of gene expression KRAS;TRPV4 GO:0008299| isoprenoid biosynthetic process FDPS;HMGCR;GGPS1 GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0032228| regulation of synaptic transmission, GABAergic CNR1;KRAS GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;KRAS GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0042127| regulation of cell proliferation PTGS1;PTGS2;FNTB GO:0008203| cholesterol metabolic process HMGCR;CAT;FDPS GO:0006694| steroid biosynthetic process CYP17A1;FDPS;HMGCR GO:0035900| response to isolation stress NAPEPLD;KRAS 18831:[DB14011 DB08053] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08053|1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0002376| immune system process SRC;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;SRC;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0043066| negative regulation of apoptotic process SRC;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0009615| response to virus CYP1A1;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;SRC;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0045453| bone resorption SRC;GPR55 GO:0070542| response to fatty acid PTGS2;CAT;SRC GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;SRC;CHRNA7 GO:0008283| cell proliferation HTR1A;GPX1;SRC;CYP1A1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0042542| response to hydrogen peroxide CAT;SRC;GPX1;SOD1;TRPA1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;SRC;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0031667| response to nutrient levels SRC;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC 18832:[DB14011 DB06090] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06090|Bradanicline CHRNA7 common genes CHRNA7 common pathways GO:1905144| CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;GLRB;TRPV1;GLRA1 GO:0007614| short-term memory CHRNA7 GO:1905906| CHRNA7 GO:0007611| learning or memory CNR1;CHRNA7 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0050808| synapse organization CHRNA7 GO:0050893| sensory processing CHRNA7 GO:0035094| response to nicotine CHRNA7;CNR1 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0098815| CHRNA7 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CHRNA7;GPR12;HTR2A GO:1901214| CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;ALOX15;TRPV4 GO:1905920| CHRNA7 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0095500| CHRNA7 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;TRPV1;GLRB;GLRA1;TRPA1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:1902991| CHRNA7 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0060078| regulation of postsynaptic membrane potential CHRNA7 GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902430| CHRNA7 GO:0006816| calcium ion transport CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8;TRPV3;CACNA1H;TRPV2;CHRNA7 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0050890| cognition CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1;CACNA1H;OPRM1;TRPV3;CHRNA7;TRPV2 GO:1900273| CHRNA7 GO:1904645| CHRNA7 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 18833:[DB14011 DB13151] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0051592| response to calcium ion FGB;AANAT;FGA GO:0031667| response to nutrient levels SOD1;F7 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;FGB;FGA GO:0009725| response to hormone stimulus ACAT1;F7 GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;FGB;GPR18;PPARG;SMPD1;FGA;CACNA1I;PLA2G1B GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;FGA;FGB GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG;F7 GO:0061844| PLA2G1B;F2 GO:1902042| FGA;GPX1;FGB GO:0043627| response to estrogen stimulus PPARG;F7 GO:0007623| circadian rhythm F7;AANAT GO:0008284| positive regulation of cell proliferation F2;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0002576| platelet degranulation FGB;SOD1;F13A1;F5;FGA;F8 GO:0045087| innate immune response FGA;PPARG;FGB GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;F8 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10;F7 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0032355| response to estradiol stimulus F7;CAT;CYP1A2;PTGS2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0031100| organ regeneration PPARG;F7 GO:0002376| immune system process FGA;IDO1;FGB GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;FGA;TRPV4;CHRNA7;FGB;HTR2A;GPR55;HMGCR;OPRM1 GO:0050714| positive regulation of protein secretion PLA2G1B;FGA;FGB GO:0001666| response to hypoxia CYP1A1;F7;CAT;CHRNA7 18834:[DB14011 DB01610] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways GO:0009636| response to toxin CAT;SLC6A14;GPX1;CYP1B1;CYP1A1 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;SLC15A2;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;SLC15A1;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8 GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC15A2;TRPV2;SLC6A14;CACNA1G;ABCC1;SLC15A1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8 GO:0006810| transport SLC6A14;TRPV2;SLC15A2;CACNA1I;TRPV1;ABCG2;ABCC1;SLC15A1 18835:[DB14011 DB11914] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11914|Lebrikizumab IL13;IL13 common genes common pathways GO:0006955| immune response CNR2;OPRD1;IL13 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;ALOX15;IDO1;TRPV1;IL13 GO:0001774| microglial cell activation IL13;TRPV1 GO:0045471| response to ethanol CAT;OPRM1;HMGCR;CNR1;SOD1;IL13 GO:0071260| cellular response to mechanical stimulus IL13;PTGS2 GO:0071345| cellular response to cytokine stimulus IL13;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation IL13;PTGS2;HMGCR GO:0035094| response to nicotine IL13;CNR1;CHRNA7 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;IL13;CYP1A1 GO:0009612| response to mechanical stimulus IL13;TRPV4;PPARG GO:0050714| positive regulation of protein secretion IL13;PLA2G1B 18836:[DB14011 DB04530] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04530|S,S-(2-Hydroxyethyl)Thiocysteine SERPINB5;PDE1B;SNX3;CYTH2;thyA;PDE4B;TYMS;PRKACA;PIM1;ARG1;icd;hemB common genes common pathways GO:0007165| signal transduction CHRNA7;PDE1B;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;PDE4B;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0061136| regulation of proteasomal protein catabolic process PRKACA;GPX1 GO:0065009| regulation of molecular function TRPV1;CYTH2 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0001975| response to amphetamine PDE1B;CNR2;SOD1 GO:0043434| response to peptide hormone stimulus TRPV1;ARG1 GO:0042053| regulation of dopamine metabolic process PDE1B;HTR1A GO:0010043| response to zinc ion ARG1;AANAT GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway ARG1;PPARG GO:0008283| cell proliferation HTR1A;PIM1;GPX1;CYP1A1 GO:0009636| response to toxin GPX1;CAT;TYMS;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TYMS;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0010269| response to selenium ion ARG1;GPX1 GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR GO:0042428| serotonin metabolic process PDE1B;HTR1A GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;TYMS GO:0001889| liver development CYP1A1;ACAT1;ARG1 GO:0048678| response to axon injury SOD1;ARG1 GO:0010976| positive regulation of neuron projection development CNR1;SNX3 GO:0008542| visual learning HMGCR;PDE1B GO:0009635| response to herbicide ARG1;CYP1A1 GO:0007565| female pregnancy ARG1;IDO1 GO:0002376| immune system process IDO1;ARG1 GO:0009611| response to wounding CYP1A1;GPX1;ARG1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PDE1B;PPARG;GPR18;PDE4B GO:0034605| cellular response to heat PRKACA;PTGS2;TRPV4;TRPV1 GO:0007568| aging TYMS;CYP1A1;CAT;ARG1;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2 GO:0042130| negative regulation of T cell proliferation ARG1;IDO1 GO:0046686| response to cadmium ion CAT;ARG1 GO:0043200| response to amino acid stimulus ARG1;GLRA3;GLRB GO:0006915| apoptotic process VDAC1;GPX1;PDE1B;PIM1 GO:0070207| protein homotrimerization TRPM8;ARG1 GO:0007626| locomotory behavior OPRM1;SOD1;PDE1B GO:0032259| methylation CYP1A2;TYMS GO:0043066| negative regulation of apoptotic process GPX1;CAT;PIM1;PTGS2;HMGCR;SOD1 GO:0034097| response to cytokine stimulus TYMS;AANAT;PTGS2 GO:0045087| innate immune response ARG1;PPARG GO:0043312| neutrophil degranulation ARG1;CAT;ALOX5 GO:0007623| circadian rhythm TYMS;AANAT GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;ARG1;CYP1A1;IDO1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E CAT;ARG1 GO:0030324| lung development ARG1;CYP1A2 GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0033189| response to vitamin A ARG1;CAT;CYP1A1;TYMS;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TYMS;CYP1A1;PPARG;TRPA1;ARG1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B GO:0030224| monocyte differentiation PPARG;PDE1B 18837:[DB14011 DB01382] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0016525| negative regulation of angiogenesis PPARG;ABCC8 GO:0099133| ABCC1;ABCC8 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;ABCC8;HTR2A;SOD1 GO:0032496| response to lipopolysaccharide CNR1;ABCC8;OPRM1;CYP1A2;PTGS2;CNR2;CYP1A1;IDO1 GO:0055085| transmembrane transport TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H;ABCC8 GO:0008542| visual learning ABCC8;HMGCR GO:0009268| response to pH ABCC8;TRPV1 GO:0007565| female pregnancy IDO1;ABCC8 GO:0061045| negative regulation of wound healing ABCC8;HMGCR GO:0010043| response to zinc ion ABCC8;AANAT GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;KCNJ1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0032868| response to insulin stimulus TRPV4;CAT;AANAT;ABCC8 GO:0034765| regulation of ion transmembrane transport CACNA1I;KCNJ1;CACNA1G;CACNA1H GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;ABCC8;CNR2;OPRM1;OPRD1 GO:0050796| regulation of insulin secretion CNR1;ABCC8 GO:0007613| memory CHRNA7;ABCC8;HTR2A;CNR1;PTGS2 18838:[DB14011 DB04707] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04707|Hydroxyfasudil ROCK1;PRKACA;PKIA common genes common pathways GO:0016525| negative regulation of angiogenesis PPARG;ROCK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;PKIA;TRPV4;PPARG GO:0043312| neutrophil degranulation CAT;ALOX5;ROCK1 GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 GO:0010628| positive regulation of gene expression TRPV4;ROCK1 GO:0006915| apoptotic process GPX1;VDAC1;ROCK1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;ROCK1;PPARG;GPR18 GO:0034605| cellular response to heat TRPV4;TRPV1;PRKACA;PTGS2 GO:1902430| CHRNA7;ROCK1 GO:0043524| negative regulation of neuron apoptosis ROCK1;SOD1 GO:0035556| intracellular signal transduction PLA2G1B;ROCK1 GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0006939| smooth muscle contraction ROCK1;HTR2A GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;ROCK1;PLA2G1B;CACNA1I GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA 18839:[DB14011 DB07448] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07448|(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid LAP3 common genes common pathways 18840:[DB14011 DB12442] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12442|Alvespimycin HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;PTGS2;OPRM1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic SOD1;CYP1A1;HSP90AA1 GO:0007165| signal transduction PPARG;HSP90AA1;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0009409| response to cold HSP90AA1;PPARG;TRPA1;TRPM8 18841:[DB14011 DB03279] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03279|Dodecyl-Alpha-D-Maltoside RARG common genes common pathways GO:0043010| camera-type eye development RARG;CYP1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;RARG;PPARG;CYP1B1 GO:0043065| positive regulation of apoptotic process RARG;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0043401| steroid hormone mediated signaling pathway PPARG;RARG GO:0006351| transcription, DNA-dependent PPARG;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0010628| positive regulation of gene expression TRPV4;RARG GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;RARG;CAT;GPX1 GO:0008284| positive regulation of cell proliferation RARG;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;RARG GO:0032526| response to retinoic acid RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;RARG 18842:[DB14011 DB08836] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0001822| kidney development CAT;ACE GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0006810| transport TRPV2;SLC15A1;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0007283| spermatogenesis ACE;SOD1;CNR1 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;SLC15A1;TRPV2;TRPV3;SLCO1A2;CACNA1H GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0060047| heart contraction GPX1;ACE;SOD1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;ACE;PPARG GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLCO1A2;TRPV3;CACNA1H;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;SLC15A1;TRPA1;GLRA1;CACNA1G 18843:[DB14011 DB00165] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00165|Pyridoxine PDXK;CYP1A1 common genes CYP1A1 common pathways GO:0007568| aging CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0009611| response to wounding CYP1A1;GPX1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0010041| response to iron(III) ion CYP1A1 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;IDO1;CYP1A1 GO:0043312| neutrophil degranulation ALOX5;PDXK;CAT GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0032094| response to food OPRM1;CYP1A1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0009308| amine metabolic process CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0032502| developmental process CYP1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;CNR1;HMGCR GO:1900087| CYP1A1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0043010| camera-type eye development CYP1A1 GO:0009624| response to nematode CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0009636| response to toxin CAT;GPX1;CYP1A1;CYP1B1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;PDXK GO:0070365| hepatocyte differentiation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:0070988| demethylation CYP1A1 GO:0009692| ethylene metabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 18844:[DB14011 DB07783] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07783|1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(3-PHENYLPROPANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE ADA common genes common pathways GO:0001666| response to hypoxia CYP1A1;ADA;CHRNA7;CAT GO:0007568| aging HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;ADA;CAT;CYP1A1 GO:0042493| response to drug ADA;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0043278| response to morphine CNR1;OPRM1;ADA GO:0033197| response to vitamin E CAT;ADA GO:0030324| lung development ADA;CYP1A2 GO:0043066| negative regulation of apoptotic process GPX1;ADA;CAT;PTGS2;HMGCR;SOD1 GO:0007155| cell adhesion CYP1B1;ADA GO:0001890| placenta development SOD1;ADA;PPARG GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0001889| liver development ADA;ACAT1;CYP1A1 GO:0042542| response to hydrogen peroxide TRPA1;ADA;GPX1;CAT;SOD1 18845:[DB14011 DB03495] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03495|4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose AMY2A;AMY2A common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;AMY2A 18846:[DB14011 DB01600] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes PTGS2;PTGS1 common pathways GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0007568| aging CYP1A1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:1902219| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0009750| response to fructose stimulus PTGS2 GO:0019372| lipoxygenase pathway GPX1;ALOX5;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning VDAC1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;CYP1A1;IDO1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TRPA1;PPARG;CYP1A1 GO:0033280| response to vitamin D PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;IDO1;ALOX15 GO:0019233| sensory perception of pain OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A;TRPA1;TRPV1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 18847:[DB14011 DB03223] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03223|Diphthamide EEF2 common genes common pathways GO:0034976| response to endoplasmic reticulum stress ALOX15;EEF2 GO:0045471| response to ethanol CAT;EEF2;CNR1;SOD1;OPRM1;HMGCR GO:0042542| response to hydrogen peroxide TRPA1;GPX1;EEF2;CAT;SOD1 GO:0007568| aging CYP1A1;EEF2;CAT;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD GO:0032355| response to estradiol stimulus CAT;EEF2;CYP1A2;PTGS2 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT;EEF2 GO:0043312| neutrophil degranulation CAT;EEF2;ALOX5 18848:[DB14011 DB06843] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways GO:0007165| signal transduction SMPD1;GPR18;PPARG;GNAS;PLA2G1B;ADCY2;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 GO:0050890| cognition GNAS;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY2;ADCY5;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;ADCY5;TRPV1;TRPV4 GO:0009791| post-embryonic development CYP1A2;GNAS GO:0035556| intracellular signal transduction ADCY2;PLA2G1B;ADCY5 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADCY2;CNR1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;ADCY5;PPARG;GPR18;ADCY2;GNAS GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;ADCY5;GNAS GO:0007626| locomotory behavior ADCY5;OPRM1;SOD1 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;GNAS;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT 18849:[DB14011 DB08675] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways GO:0006631| fatty acid metabolic process PTGIS;ALOX15;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;PTGIS;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0050728| negative regulation of inflammatory response CNR2;PTGIS GO:0046697| decidualization PTGS2;PTGIS GO:0071456| cellular response to hypoxia PTGIS;SLC29A1;PTGS2;OPRD1 GO:0045766| positive regulation of angiogenesis CYP1B1;PTGIS;CHRNA7 GO:0006693| prostaglandin metabolic process PTGIS;PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGIS;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG;GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2;PTGIS GO:0007566| embryo implantation PTGS2;SOD1;PTGIS GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGIS;PTGS2 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;PTGIS GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGIS;PTGS2;PTGS1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;PTGIS;CYP1B1 GO:0001516| prostaglandin biosynthetic process PTGIS;PTGS1;PTGS2 18850:[DB14011 DB03595] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03595|CRA_9785 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18851:[DB14011 DB00926] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00926|Etretinate RARA;RXRA;RARB;RXRG;RXRB;RARG;CYP19A1;CYP26A1;CRABP1 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;RARA GO:0007565| female pregnancy IDO1;RARA GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0016032| viral reproduction RXRA;VDAC1;HTR2A GO:0051289| protein homotetramerization RXRG;TRPM8;TRPV1;TRPA1;RXRA;CRYZ;CAT GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0001889| liver development ACAT1;RARA;CYP1A1 GO:0006351| transcription, DNA-dependent RARA;RARG;RARB;RXRG;PPARG;RXRA;RXRB GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRB;RXRA;RARB;RXRG;RARA;RARG GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;RARA;CAT GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP19A1;CYP26A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP26A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;RARB;IDO1;SMPD1;PPARG;RARG;PTGS2;SOD1;CNR1 GO:0007507| heart development PPARG;RXRA GO:0001890| placenta development RXRA;PPARG;SOD1 GO:0008285| negative regulation of cell proliferation RARG;RARA;OPRM1;PTGS2;RARB;CYP1B1;PPARG GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;RXRA;CYP1A1;PPARG GO:0007566| embryo implantation RXRA;PTGS2;SOD1 GO:0022008| neurogenesis DAGLA;RARB GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0043010| camera-type eye development RARG;RXRA;CYP1A1 GO:0007165| signal transduction RARB;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;RARA;CRABP1;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;CYP19A1 GO:0045893| positive regulation of transcription, DNA-dependent RARA;RXRA;PPARG GO:0006355| regulation of transcription, DNA-dependent RARG;RARA;RXRG;RARB;RXRA;RXRB;PPARG GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP19A1;CYP1A1;CYP2C9;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP26A1;CYP1A2;HMGCR GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;CYP19A1 GO:0033189| response to vitamin A CAT;RARA;CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARA;RARG;PPARG;RXRB;RXRA;RARB;RXRG GO:0008203| cholesterol metabolic process HMGCR;CAT;RXRA GO:0032526| response to retinoic acid RXRA;PPARG;RARG;RARA GO:0043066| negative regulation of apoptotic process RARB;RARA;GPX1;RARG;CAT;HMGCR;PTGS2;SOD1 GO:0071300| cellular response to retinoic acid PPARG;RARA;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;RARG;RXRB;RXRA;PPARG;RARB;PLA2G1B;RXRG GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;RARG;CHRNA7;RARA;RARB GO:0034097| response to cytokine stimulus PTGS2;RARA;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;RARA;RARB;TRPV4;TRPV1;RXRA;PPARG GO:0043277| apoptotic cell clearance ALOX15;RARA GO:0007283| spermatogenesis RARA;CNR1;SOD1 GO:0010628| positive regulation of gene expression RARG;RARA;TRPV4 GO:0001657| ureteric bud development RARB;CAT;RARA GO:0045892| negative regulation of transcription, DNA-dependent PPARG;RARA GO:0032355| response to estradiol stimulus RARA;CAT;CYP1A2;PTGS2 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7;RARA 18852:[DB14011 DB11611] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11611|Lifitegrast ITGAL;CYP2C9;SLCO1A2;SLCO2B1 common genes CYP2C9 common pathways GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;SLCO2B1;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;SLCO1A2;TRPV3;CACNA1H;TRPV2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0043312| neutrophil degranulation ITGAL;ALOX5;CAT GO:0007155| cell adhesion ITGAL;CYP1B1 GO:0019627| urea metabolic process CYP2C9 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;SLCO1A2;SLCO2B1;TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPA1;GLRA1;CACNA1G GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;ITGAL;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0043603| cellular amide metabolic process CYP2C9 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;ALOX5;PTGS1;ITGAL;PTGS2;CNR2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG 18853:[DB14011 DB00039] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00039|Palifermin FGFR2;NRP1;FGFR1;FGFR4;FGFR3;HSPG2 common genes common pathways GO:0043406| positive regulation of MAP kinase activity FGFR1;HTR2A GO:0010628| positive regulation of gene expression TRPV4;FGFR4 GO:0001657| ureteric bud development FGFR2;CAT;FGFR1 GO:0140059| NRP1;CHRNA7 GO:0031532| actin cytoskeleton reorganization NRP1;TRPV4 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;NRP1 GO:0006915| apoptotic process VDAC1;FGFR3;FGFR2;GPX1 GO:0030855| epithelial cell differentiation PPARG;VDAC1;FGFR2 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGFR3;TRPV4;ALOX15;FGFR4;OPRM1;HMGCR;GPR55;NRP1;HTR2A;FGFR2;CHRNA7 GO:0043085| positive regulation of catalytic activity SOD1;FGFR4 GO:0007605| sensory perception of sound FGFR1;SOD1;GPX1 GO:0042593| glucose homeostasis CNR1;PPARG;FGFR4;TRPV4 GO:0030282| bone mineralization FGFR2;PTGS2;ALOX15;FGFR3 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FGFR1 GO:0048514| blood vessel morphogenesis CYP1B1;FGFR1 GO:0010468| regulation of gene expression CYP1A2;FGFR1 GO:0009611| response to wounding CYP1A1;GPX1;NRP1 GO:0051897| positive regulation of protein kinase B signaling cascade FGFR2;GPX1;FGFR1;FGFR4;FGFR3 GO:0016525| negative regulation of angiogenesis PPARG;HSPG2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;FGFR2 GO:0006355| regulation of transcription, DNA-dependent FGFR1;PPARG GO:0007413| axonal fasciculation NRP1;CNR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR2;FGFR1;TRPV1;TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG;FGFR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;FGFR2 GO:0008284| positive regulation of cell proliferation FGFR3;FGFR4;PTGS2;HMGCR;FGFR1;HTR1A;HTR2A;FGFR2;CHRNA7 GO:0043542| endothelial cell migration NRP1;CYP1B1 GO:0030324| lung development FGFR1;CYP1A2;FGFR2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;FGFR2;CYP1A1;IDO1 GO:0042127| regulation of cell proliferation FGFR1;PTGS2;PTGS1 GO:0042060| wound healing OPRM1;FGFR2;ALOX15 GO:0001523| retinoid metabolic process NAPEPLD;HSPG2 GO:0051781| positive regulation of cell division FGFR2;CAT GO:0009791| post-embryonic development FGFR2;CYP1A2 GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;NRP1;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0007420| brain development ACAT1;HSPG2;FGFR1 GO:0019216| regulation of lipid metabolic process FGFR4;CYP1A1;PPARG;CNR1;HMGCR GO:0040014| regulation of multicellular organism growth FGFR2;SOD1 GO:0048565| digestive tract development CYP1A1;FGFR2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation NRP1;HTR2A GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;HSPG2;TRPV1;IDO1;ALOX15 GO:0010976| positive regulation of neuron projection development CNR1;FGFR1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;NRP1 GO:0043524| negative regulation of neuron apoptosis NRP1;SOD1 GO:0010629| negative regulation of gene expression FGFR1;OPRD1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;HSPG2;PTGS2;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0045165| cell fate commitment FGFR2;PPARG GO:0007399| nervous system development NRP1;GLRB;SMPD1 GO:0007507| heart development PPARG;NRP1 GO:0006351| transcription, DNA-dependent PPARG;FGFR1 GO:0001525| angiogenesis CYP1B1;FGFR1;NRP1;HSPG2;PTGS2;FGFR2 GO:0048469| cell maturation PPARG;FGFR1 GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;FGFR2;CAT 18854:[DB14011 DB02966] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02966|Fluoro-Willardiine GRIA2 common genes common pathways GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;TRPV2;GRIA2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8 GO:0007165| signal transduction GRIA2;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;GRIA2;GLRA1;CACNA1G;GLRB;VDAC1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GRIA2;TRPA1;GLRA1;TRPV1;GLRB GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;GRIA2;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 18855:[DB14011 DB06699] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06699|Degarelix GNRHR common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;GNRHR;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GNRHR;GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A 18856:[DB14011 DB03314] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03314|Fluorotryptophane TPI1;GSTM1 common genes common pathways GO:0008152| metabolic process TPI1;ACAT1;GSTM1;SMPD1 GO:0042178| xenobiotic catabolic process GSTM1;CRYZ GO:0006749| glutathione metabolic process GPX1;SOD1;GSR;GSTM1 18857:[DB14011 DB01400] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01400|Neostigmine ACHE;BCHE common genes common pathways GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;BCHE;TRPA1;PPARG;CYP1A1;ABCG2 GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion CYP1B1;ACHE GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;BCHE;CYP1B1 GO:0008283| cell proliferation GPX1;HTR1A;ACHE;CYP1A1 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 18858:[DB14011 DB04972] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04972|Canfosfamide GSTP1 common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;GSR;GSTP1 GO:0000302| response to reactive oxygen species SOD1;GPX1;CAT;GSTP1 GO:0098869| GSR;GSTP1;PTGS2;CAT;GPX1;PTGS1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032355| response to estradiol stimulus GSTP1;PTGS2;CYP1A2;CAT GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0043200| response to amino acid stimulus GLRA3;GSTP1;GLRB GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;GSTP1 GO:0008152| metabolic process GSTP1;SMPD1;ACAT1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;GSTP1 GO:1904706| PPARG;GSTP1 GO:0031667| response to nutrient levels GSTP1;SOD1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B GO:0032930| positive regulation of superoxide anion generation SOD1;GSTP1 GO:0006749| glutathione metabolic process GSTP1;GSR;SOD1;GPX1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0009636| response to toxin CAT;GPX1;CYP1B1;GSTP1;CYP1A1 18859:[DB14011 DB04774] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04774|Reidispongiolide A ACTA1 common genes common pathways GO:0010226| response to lithium ion PTGS2;ACTA1 GO:0006936| muscle contraction CACNA1H;ACTA1;GLRA1 GO:0048741| skeletal muscle fiber development ACTA1;GPX1 GO:0010628| positive regulation of gene expression ACTA1;TRPV4 GO:0009612| response to mechanical stimulus ACTA1;TRPV4;PPARG 18860:[DB14011 DB06822] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0009314| response to radiation CAT;CXCL12;PTGS2;OPRM1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain CXCL12;HTR2A;TRPA1 GO:0051924| regulation of calcium ion transport OPRD1;CXCL12 GO:0007595| lactation SERPINC1;SLC29A1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;CXCL12;TRPV1 GO:0006955| immune response OPRD1;CNR2;CXCL12 GO:0009408| response to heat TRPV1;TRPV2;TRPV3;CXCL12;SOD1 GO:0043434| response to peptide hormone stimulus TRPV1;CXCL12 GO:0071345| cellular response to cytokine stimulus TRPV1;ITGA4 GO:0007420| brain development CXCL12;ACAT1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CXCL12;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0008344| adult locomotory behavior OPRD1;CXCL12 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0090280| positive regulation of calcium ion import CXCL12;TRPV3;TRPV2 GO:0061844| CXCL12;PLA2G1B GO:0007584| response to nutrient SERPINC1;CNR1;HMGCR;PPARG GO:0007155| cell adhesion CYP1B1;CXCL12;ITGA4 GO:0009612| response to mechanical stimulus PPARG;TRPV4;CXCL12 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;CXCL12;HTR2A;HTR1A;CHRNA7 GO:0009615| response to virus CXCL12;CYP1A1 GO:0060326| cell chemotaxis CXCL12;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;CXCL12;OPRM1;OPRD1;PPARG;GPR18 GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CXCL12;CHRNA7;TRPM8;TRPV4 GO:0031100| organ regeneration CXCL12;PPARG GO:0001666| response to hypoxia CHRNA7;CAT;CXCL12;CYP1A1 18861:[DB14011 DB00200] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0006749| glutathione metabolic process SOD1;GPX1;MMACHC;GSR GO:0009791| post-embryonic development CYP1A2;MUT GO:0006811| ion transport TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TCN1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;TCN2;GLRA3 GO:0015889| cobalamin transport CUBN;AMN;TCN2;TCN1;ABCC1 GO:0007399| nervous system development MTR;GLRB;SMPD1 GO:0042953| lipoprotein transport CUBN;PPARG GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;CUBN;NAAA;PTGS1;GPX1;CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 GO:0008152| metabolic process MUT;SMPD1;ACAT1 GO:0070988| demethylation CYP1A1;MMACHC GO:0048678| response to axon injury MTR;SOD1 GO:0042359| vitamin D metabolic process CYP3A4;CUBN;CYP1A1 GO:0009235| cobalamin metabolic process ABCC1;MMAB;MUT;MMAA;MMACHC;TCN1;TCN2;AMN;CUBN;MTRR;MTR GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP2C9;CYP1A1;CUBN;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;IDO1;GSR;CYP2C19;MMACHC;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;PTGS1;ALOX5;GPX1;MTRR GO:0043312| neutrophil degranulation CAT;ALOX5;TCN1 GO:0032259| methylation CYP1A2;MTRR;MTR GO:0008203| cholesterol metabolic process HMGCR;CUBN;CAT 18862:[DB14011 DB05578] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05578|Ramucirumab KDR common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0043066| negative regulation of apoptotic process KDR;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;KDR;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;KDR GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0016032| viral reproduction HTR2A;VDAC1;KDR GO:0001525| angiogenesis PTGS2;CYP1B1;KDR 18863:[DB14011 DB07187] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07187|6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE AKR1B1 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;AKR1B1;TRPA1 GO:0043066| negative regulation of apoptotic process AKR1B1;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;AKR1B1 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;AKR1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;PTGS1;ALOX5;GPX1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;AKR1B1 18864:[DB14011 DB03974] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03974|L-Homoarginine NOS3 common genes common pathways GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 GO:0042311| vasodilation NOS3;GPX1 GO:0030324| lung development CYP1A2;NOS3 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1;CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;NOS3;GSR;IDO1;CYP2C19;CYP1B1 GO:0045454| cell redox homeostasis GPX1;NOS3;GSR GO:1902042| GPX1;NOS3 GO:0008217| regulation of blood pressure PPARG;NOS3;SOD1;PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;NOS3;PPARG GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0045776| negative regulation of blood pressure NOS3;CNR1 GO:0001525| angiogenesis PTGS2;NOS3;CYP1B1 GO:0009408| response to heat NOS3;TRPV1;TRPV2;SOD1;TRPV3 GO:0019430| removal of superoxide radicals SOD1;NOS3 18865:[DB14011 DB04089] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04089|AL5300 CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;PTGS2;CYP1A2;SOD1 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG 18866:[DB14011 DB08165] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08165|indane-5-sulfonamide CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1;CA2 18867:[DB14011 DB09564] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09564|Insulin Degludec INSR common genes common pathways GO:0000187| activation of MAPK activity INSR;PLA2G1B;SOD1;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;INSR;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;TRPV1;OPRM1;PTGS2 GO:0006355| regulation of transcription, DNA-dependent INSR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0007612| learning PTGS2;INSR;VDAC1 GO:0008284| positive regulation of cell proliferation INSR;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0045740| positive regulation of DNA replication PLA2G1B;INSR GO:0032869| cellular response to insulin stimulus INSR;PPARG;PLA2G1B GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7;INSR GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0035556| intracellular signal transduction PLA2G1B;INSR 18868:[DB14011 DB14517] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation APP;PPARG;CYP1B1;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PTGS1;ATP1A1;SOD1;PTGS2;PPARG GO:0061844| APP;PLA2G1B GO:0032930| positive regulation of superoxide anion generation APP;SOD1 GO:0001895| retina homeostasis ALB;TF;SOD1 GO:0008344| adult locomotory behavior OPRD1;APP GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA3;ATP1A1;CACNA1H;TRPV3;TF;CHRNA7;TRPV2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;APP GO:1900273| CHRNA7;APP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;APP GO:0007613| memory APP;CNR1;HTR2A;PTGS2;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;APP;TRPV4;TRPV1 GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0006879| cellular iron ion homeostasis SOD1;TF;ABCG2 GO:0008542| visual learning HMGCR;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;APP;PLA2G1B GO:1902004| CHRNA7;APP GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:0007268| synaptic transmission OPRD1;OPRM1;GLRA3;HTR2A;VDAC1;GLRB;APP;CACNA1G;GLRA1 GO:0010629| negative regulation of gene expression OPRD1;APP GO:0071320| cellular response to cAMP AANAT;APP GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:1990090| TRPV1;APP GO:0007399| nervous system development GLRB;SMPD1;APP GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;APP;SMPD1;IDO1;TRPV1;CYP1B1 GO:0001774| microglial cell activation TRPV1;APP GO:0051262| protein tetramerization APP;CAT;HMGCR GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0010628| positive regulation of gene expression TRPV4;APP GO:0000187| activation of MAPK activity APP;PLA2G1B;SOD1;CHRNA7 GO:0006915| apoptotic process APP;VDAC1;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;APP GO:0086002| CACNA1G;ATP1A1 GO:0034220| ion transmembrane transport TRPV1;GLRB;GLRA1;TRPA1;CHRNA7;ATP1A1;GLRA3 GO:0098869| GSR;ALB;CAT;PTGS1;GPX1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress APP;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;APP GO:0010468| regulation of gene expression APP;CYP1A2 GO:0098815| CHRNA7;APP GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;APP;GPR18;PPARG GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0019731| antibacterial humoral response PLA2G1B;APP GO:0050808| synapse organization CHRNA7;APP GO:0042493| response to drug CAT;CYP1A2;PTGS2;ATP1A1;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG GO:0050830| defense response to Gram-positive bacterium APP;PLA2G1B GO:0010288| response to lead ion CAT;APP GO:0045087| innate immune response PPARG;APP GO:0007155| cell adhesion CYP1B1;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;PPARG;TRPV4;TRPV1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0002576| platelet degranulation SOD1;TF;ALB;APP GO:0007626| locomotory behavior SOD1;OPRM1;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;APP GO:0046330| positive regulation of JNK cascade APP;TRPV4 GO:1905906| CHRNA7;APP GO:0007611| learning or memory CHRNA7;CNR1;APP GO:0008203| cholesterol metabolic process HMGCR;CAT;APP GO:0007612| learning PTGS2;APP;VDAC1 18869:[DB14011 DB01212] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0008283| cell proliferation CYP1A1;GPX1;GLUL;HTR1A GO:0006811| ion transport TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;CACNA1G;SLC15A1;GLRA1;TRPA1;TRPV2;CHRNA7;SLC22A11;CACNA1H;TRPV3;SLC22A8;SLC15A2;GLRA3 GO:0001895| retina homeostasis ALB;SOD1 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0098869| CAT;PTGS1;GPX1;PTGS2;ALB;GSR GO:0051260| protein homooligomerization ACAT1;GLUL;GLRA3;SLC22A6;GLRA1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0006810| transport ABCC1;SLC15A1;TRPV1;CACNA1I;ABCG2;SLC15A2;TRPV2 GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:0055085| transmembrane transport TRPV2;SLC22A11;CACNA1H;TRPV3;SLC22A8;SLC15A2;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;SLC22A6;ABCC1;TRPA1;SLC15A1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0002576| platelet degranulation SOD1;ALB 18870:[DB14011 DB07660] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07660|AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0008284| positive regulation of cell proliferation F2;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 18871:[DB14011 DB03476] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03476|Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine PLAU common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLAU;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLAU GO:0001666| response to hypoxia PLAU;CYP1A1;CHRNA7;CAT 18872:[DB14011 DB02633] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02633|Cibacron Blue NQO1;GSTP1 common genes common pathways GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GSTP1;GPR18 GO:0098869| GSR;GSTP1;CAT;PTGS1;GPX1;PTGS2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;NQO1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;GSTP1;NQO1 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT;CYP1A1;NQO1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0043200| response to amino acid stimulus GLRB;GSTP1;GLRA3 GO:0043066| negative regulation of apoptotic process GSTP1;NQO1;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0043312| neutrophil degranulation GSTP1;ALOX5;CAT GO:0000302| response to reactive oxygen species SOD1;CAT;GPX1;GSTP1 GO:0034599| cellular response to oxidative stress GSTP1;GSR;SOD1;GPX1;CAT GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9;NQO1 GO:0032869| cellular response to insulin stimulus GSTP1;PLA2G1B;PPARG GO:0006749| glutathione metabolic process GSTP1;GSR;SOD1;GPX1 GO:0070301| cellular response to hydrogen peroxide NQO1;CYP1B1 GO:0007584| response to nutrient PPARG;NQO1;HMGCR;CNR1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;NQO1;CYP1B1;GSTP1 GO:0014070| response to organic cyclic compound NQO1;PPARG;CYP1A1;TRPA1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0006809| nitric oxide biosynthetic process NQO1;CYP1B1 GO:0008152| metabolic process SMPD1;GSTP1;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;GSTP1;CYP1B1;NQO1;CYP2C9 GO:0045471| response to ethanol NQO1;GSTP1;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0019430| removal of superoxide radicals NQO1;SOD1 GO:1904706| GSTP1;PPARG GO:0031667| response to nutrient levels SOD1;GSTP1 18873:[DB14011 DB08166] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08166|(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile PIM1 common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0006915| apoptotic process PIM1;GPX1;VDAC1 18874:[DB14011 DB06931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1 GO:0008299| isoprenoid biosynthetic process HMGCR;GGPS1 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;GGPS1 18875:[DB14011 DB08176] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08176|(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOB;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0042493| response to drug ABCG2;MAOB;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0022900| electron transport chain MAOB;IDO1;GSR;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;MAOB;IDO1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;MAOB;SOD1;CYP1A2 GO:0045471| response to ethanol MAOB;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0010269| response to selenium ion GPX1;MAOB GO:0009636| response to toxin CAT;GPX1;CYP1A1;MAOB;CYP1B1 GO:0051412| response to corticosterone stimulus AANAT;MAOB 18876:[DB14011 DB13144] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13144|Lenograstim CSF3R common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;CSF3R;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0007155| cell adhesion CSF3R;CYP1B1 GO:0030593| neutrophil chemotaxis PLA2G1B;CSF3R 18877:[DB14011 DB06191] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCB1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0055085| transmembrane transport SLCO1B1;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1 GO:0006810| transport TRPV2;ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8;TRPV3;CACNA1H;SLCO1B1;GLRA3;TRPV2;CHRNA7 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 18878:[DB14011 DB08104] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0006810| transport TTR;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 18879:[DB14011 DB00884] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00884|Risedronate FDPS;PTGS2 common genes PTGS2 common pathways GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;HMGCR;FDPS GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:1902219| PTGS2 GO:0007568| aging CYP1A1;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| PTGS2;HMGCR GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0008299| isoprenoid biosynthetic process FDPS;HMGCR GO:0045540| regulation of cholesterol biosynthetic process HMGCR;FDPS GO:0034612| response to tumor necrosis factor PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0008203| cholesterol metabolic process HMGCR;FDPS;CAT GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;IDO1 GO:0006695| cholesterol biosynthetic process HMGCR;FDPS GO:0071284| cellular response to lead ion PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0006694| steroid biosynthetic process CYP17A1;FDPS;HMGCR GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1;TRPA1;TRPV1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:1990776| PTGS2 GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;FDPS;PTGS1;NAAA;GPX1;CYP2C9;PPARG;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0016032| viral reproduction VDAC1;HTR2A;FDPS GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 18880:[DB14011 DB01014] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes PTGS2;PPARG;ALOX5;PTGS1 common pathways GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:2001300| ALOX5 GO:0031000| response to caffeine PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0007568| aging CYP1A1;CAT;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2 GO:0015909| long-chain fatty acid transport PPARG GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1902219| PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0043388| positive regulation of DNA binding PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0030224| monocyte differentiation PPARG GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0009750| response to fructose stimulus PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0071455| cellular response to hyperoxia PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071284| cellular response to lead ion PTGS2 GO:0032526| response to retinoic acid PPARG GO:0030308| negative regulation of cell growth PPARG GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0042594| response to starvation PPARG;ACAT1 GO:0043312| neutrophil degranulation CAT;ALOX5 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0033280| response to vitamin D PTGS2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0007566| embryo implantation PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:1905461| PPARG GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0061614| PPARG GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ALOX5;PTGS1;CNR2;PTGS2 GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1 GO:0006351| transcription, DNA-dependent PPARG GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0048469| cell maturation PPARG GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:1990776| PTGS2 GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 18881:[DB14011 DB04334] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0046677| response to antibiotic SOD1;CYP1A1;AOC3 GO:0007155| cell adhesion AOC3;CYP1B1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;AOC3;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0009308| amine metabolic process CYP1A1;AOC3 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;AOC3;CYP3A5;CYP2C19;CYP2D6 GO:0006954| inflammatory response TRPV1;AOC3;ALOX15;IDO1;PTGS2;CNR2;PTGS1;ALOX5 18882:[DB14011 DB14041] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14041|Fremanezumab CALCA;CALCB common genes common pathways GO:0045776| negative regulation of blood pressure CALCA;CNR1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CALCB;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7 GO:0061844| PLA2G1B;CALCA GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;CALCA;PPARG GO:0045087| innate immune response CALCA;PPARG GO:0043542| endothelial cell migration CALCA;CYP1B1 GO:0050830| defense response to Gram-positive bacterium CALCA;PLA2G1B GO:0019731| antibacterial humoral response PLA2G1B;CALCA GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;TRPV4;CALCB;TRPM8 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CALCA;CALCB;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;CALCA;GPR18 GO:0045671| negative regulation of osteoclast differentiation CALCA;GPR55 18883:[DB14011 DB07061] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07061|1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL NMT2 common genes common pathways 18884:[DB14011 DB05265] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05265|Ecabet NOXO1;ureC common genes common pathways GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;NOXO1;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0006801| superoxide metabolic process SOD1;NOXO1 GO:0043085| positive regulation of catalytic activity NOXO1;SOD1 18885:[DB14011 DB05479] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05479|CZEN 002 MC1R common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1;MC1R GO:0032720| negative regulation of tumor necrosis factor production MC1R;GPR18;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PPARG;MC1R;GPR18 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MC1R GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;MC1R;PPARG GO:0009650| UV protection MC1R;CAT;GPX1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;MC1R;PPARG;SMPD1 GO:0035556| intracellular signal transduction PLA2G1B;MC1R 18886:[DB14011 DB00993] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes CYP1A2 common pathways GO:0051289| protein homotetramerization HPRT1;TRPV1;TRPM8;TRPA1;CRYZ;CAT GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;RAC1;CNR2;PTGS2;ALOX5;PTGS1 GO:0007595| lactation SLC29A1;XDH GO:0010629| negative regulation of gene expression XDH;OPRD1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;RAC1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;RAC1;TRPV1;CYP1B1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0035556| intracellular signal transduction PLA2G1B;RAC1 GO:0008152| metabolic process ACAT1;GSTA2;GSTA1;GSTM1;SMPD1 GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0071260| cellular response to mechanical stimulus PTGS2;RAC1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0006749| glutathione metabolic process GSTA2;SOD1;GPX1;GSTM1;GSR;GSTA1 GO:0042178| xenobiotic catabolic process GSTM1;CRYZ GO:0045740| positive regulation of DNA replication RAC1;PLA2G1B GO:0006139| nucleobase-containing compound metabolic process TPMT;SLC29A1 GO:0045333| cellular respiration CYP1A2 GO:0008283| cell proliferation GPX1;HTR1A;RAC1;CYP1A1 GO:0006919| activation of caspase activity XDH;PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0045453| bone resorption RAC1;GPR55 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0010811| positive regulation of cell-substrate adhesion ALOX15;RAC1 GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0001975| response to amphetamine HPRT1;SOD1;CNR2 GO:0007015| actin filament organization RAC1;TRPV4;PLA2G1B GO:0042493| response to drug ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0022900| electron transport chain CYP1A2;XDH;GSR;IDO1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;XDH;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;PTGS1;ALOX5;GPX1 GO:0007626| locomotory behavior OPRM1;SOD1;HPRT1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0032259| methylation TPMT;CYP1A2 GO:0035722| interleukin-12-mediated signaling pathway GSTA2;SOD1 GO:0007155| cell adhesion RAC1;CYP1B1 GO:0043312| neutrophil degranulation CAT;ALOX5;RAC1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;IDO1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0030855| epithelial cell differentiation GSTA2;PPARG;GSTA1;VDAC1 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSTA1;GSR GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0009611| response to wounding GPX1;RAC1;CYP1A1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;RAC1;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0010468| regulation of gene expression CYP1A2 GO:0035025| positive regulation of Rho protein signal transduction RAC1;GPR18;GPR55 18887:[DB14011 DB01677] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01677|Fumaric Acid mdh;ME2;FAH common genes common pathways GO:0008152| metabolic process SMPD1;ME2;ACAT1;FAH GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ME2;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0022900| electron transport chain CYP1A2;ME2;IDO1;GSR 18888:[DB14011 DB01056] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes CYP1A2 common pathways GO:0098869| GSR;ALB;CAT;PTGS1;GPX1;PTGS2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0086002| SCN5A;CACNA1G GO:0055085| transmembrane transport TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;ABCC1;CACNA1G;SCN5A;TRPV2;TRPV3;CACNA1H GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0086015| SCN5A;CACNA1G GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;IDO1;CYP1A1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0086016| SCN5A;CACNA1G GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0034765| regulation of ion transmembrane transport SCN5A;CACNA1H;CACNA1I;CACNA1G GO:0097267| CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN5A GO:0086046| SCN5A;CACNA1G GO:0086045| CACNA1G;SCN5A GO:0045333| cellular respiration CYP1A2 GO:0006811| ion transport TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPA1;GLRA1;CACNA1G;CHRNA7;SCN5A;TRPV2;GLRA3;TRPV3;CACNA1H GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;PTGS2;CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0001895| retina homeostasis ALB;SOD1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 GO:0002027| regulation of heart rate CACNA1G;SCN5A GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0086091| SCN5A;CACNA1G GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0071277| cellular response to calcium ion SCN5A;ALOX15 GO:0019228| regulation of action potential in neuron CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0035725| sodium ion transmembrane transport CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0086010| CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 18889:[DB14011 DB04876] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04876|Vildagliptin DPP4 common genes common pathways GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DPP4 18890:[DB14011 DB02393] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02393|D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate PFKFB1 common genes common pathways GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 GO:0032868| response to insulin stimulus TRPV4;PFKFB1;AANAT;CAT GO:0008152| metabolic process SMPD1;PFKFB1;ACAT1 GO:0045821| positive regulation of glycolysis PFKFB1;HTR2A GO:0031100| organ regeneration PPARG;PFKFB1 GO:0051591| response to cAMP AANAT;PFKFB1 GO:0042594| response to starvation ACAT1;PFKFB1;PPARG 18891:[DB14011 DB08057] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways GO:0006919| activation of caspase activity LCK;PPARG GO:0030217| T cell differentiation GPR18;LCK GO:0016032| viral reproduction LCK;VDAC1;HTR2A GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;LCK;TRPV1 GO:0042127| regulation of cell proliferation LCK;PTGS2;PTGS1 GO:0045087| innate immune response PPARG;LCK GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;LCK;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;LCK 18892:[DB14011 DB07766] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07766|(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} CAMK2A;CDK16 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;CAMK2A GO:0006816| calcium ion transport TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;CAMK2A;TRPV2;CHRNA7;CACNA1H;TRPV3 GO:0035556| intracellular signal transduction CAMK2A;PLA2G1B GO:0007399| nervous system development SMPD1;GLRB;CAMK2A GO:0007283| spermatogenesis CDK16;SOD1;CNR1 GO:0010666| positive regulation of cardiac muscle cell apoptosis CAMK2A;HMGCR 18893:[DB14011 DB11077] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0006691| leukotriene metabolic process ALOX5;CYP4A11;ALOX15;ABCC1 GO:0022900| electron transport chain ADH5;GSR;IDO1;CYP1A2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;CYP4A11;ALOX15 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP4A11;CYP1A2;CYP3A7;PTGS2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;ADH5 GO:0019369| arachidonic acid metabolic process FAAH;CYP4A11;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0009308| amine metabolic process CYP1A1;SULT1A1 GO:0008210| estrogen metabolic process CYP1B1;SULT1A1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;IDO1;ADH5 GO:0030308| negative regulation of cell growth ENPP1;PPARG GO:0009812| flavonoid metabolic process SULT1A1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP4A11;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;SULT1A1;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1A1;CYP2C9 GO:0006955| immune response CNR2;OPRD1;ENPP1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;SULT1A1;CYP1B1 GO:0008152| metabolic process ACAT1;ENPP1;SMPD1 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;SULT1A1;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0045777| positive regulation of blood pressure ADH5;CNR1 GO:0001523| retinoid metabolic process ADH5;NAPEPLD GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;CYP4A11;HMGCR GO:0032869| cellular response to insulin stimulus PPARG;ENPP1;PLA2G1B GO:0097267| CYP1A2;CYP4A11;CYP2C9;CYP1A1;CYP1B1;CYP2C19 18894:[DB14011 DB11093] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes CACNA1H;CACNA1I;CACNA1G common pathways GO:0007605| sensory perception of sound GPX1;CACNA1D;SOD1 GO:0043085| positive regulation of catalytic activity CIB1;SOD1 GO:0006874| cellular calcium ion homeostasis RGN;GPR12;HTR2A;TPT1;SLC8A1;RYR1;CASR;CHRNA7;RYR3;CALR;TRPV4;RYR2;TRPM8 GO:0098869| GSR;ALB;CAT;GPX1;PTGS1;PTGS2 GO:0006936| muscle contraction CACNA1S;GLRA1;CACNA1H;RYR1;SLC8A1;CALM1 GO:1901214| CHP1;CHRNA7 GO:0042391| regulation of membrane potential CACNA1H;GLRB;CACNA1G;GLRA1 GO:0007635| chemosensory behavior TRPV1;CASR GO:0007568| aging CANX;CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;RGN;HTR2A;SOD1;CNR1 GO:0006810| transport CACNB3;CACNA1E;ABCC1;ABCG2;CACNB1;TRPV1;CACNA1I;SRI;CACNB4;TRPV2 GO:0071456| cellular response to hypoxia CASR;SLC8A1;SLC29A1;S100B;PTGS2;OPRD1 GO:0034605| cellular response to heat PDCD6;TRPV1;TRPV4;PTGS2 GO:0051209| release of sequestered calcium ion into cytosol RYR3;TRPA1;RYR2;TRPV1;HTR2A;RYR1 GO:0032355| response to estradiol stimulus CALR;CAT;CYP1A2;PTGS2 GO:0071468| cellular response to acidity PKD1L3;CHP1;TRPV1;PKD2L1 GO:0086027| CACNA1G GO:0086018| CACNA1G GO:0007186| G-protein coupled receptor signaling pathway CALM1;CASR;CALM3;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PPARG;GPR18;CALM2 GO:0071363| cellular response to growth factor stimulus OPRD1;SPARC;CAT;TRPV1;CIB1 GO:0051968| positive regulation of synaptic transmission, glutamatergic NRXN1;PTGS2 GO:0010033| response to organic substance CASQ1;SOD1;PTGS2;CYP1A2;PPARG;CYP1A1;CALR;TRPA1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CALR GO:0051262| protein tetramerization CAT;HMGCR;TRPV5 GO:0031000| response to caffeine PPARG;RYR2;RYR1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;NRXN1 GO:0048741| skeletal muscle fiber development GPX1;RYR1 GO:0071356| cellular response to tumor necrosis factor CIB1;TRPV1 GO:0010977| negative regulation of neuron projection development TRPV4;CIB1 GO:0046688| response to copper ion AANAT;S100A13;SOD1 GO:0010628| positive regulation of gene expression CASR;CALR;TRPV4 GO:0001666| response to hypoxia CHRNA7;CAT;RYR1;SLC8A1;CYP1A1;RYR2 GO:0007283| spermatogenesis SOD1;CNR1;RGN;CALR3;CATSPER1;CALR;CIB1 GO:0006915| apoptotic process GPX1;CASR;VDAC1;CIB1;PDCD6 GO:0045766| positive regulation of angiogenesis PDCD6;CYP1B1;CHRNA7 GO:0008219| cell death CACNA1A;HTR2A GO:0055085| transmembrane transport TRPV3;CACNA1H;RYR1;CACNA1C;CACNA1D;SLC8A1;TRPV2;CALM1;ABCC1;RYR3;CACNA1E;CACNA1S;CATSPER1;TRPV5;CACNA1G;TRPA1;TRPV6;RYR2;CACNA1F;VDAC1;TRPV4;CACNA1I;CACNA1A;TRPV1;TRPM8;ABCG2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;CIB1;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0086002| CACNA1C;CACNA1D;CACNA1G GO:0034220| ion transmembrane transport CHRNA7;S100A6;RYR1;GLRA3;CASQ1;CASQ2;RYR2;TRPV1;GLRB;TRPA1;GLRA1;RYR3 GO:0051591| response to cAMP SPARC;AANAT GO:0046686| response to cadmium ion CAT;SPARC GO:0010288| response to lead ion SPARC;CAT GO:0035307| positive regulation of protein dephosphorylation CALM3;CALM1;SMPD1;CALM2 GO:0043312| neutrophil degranulation CAT;ALOX5;GCA GO:0035902| response to immobilization stress CYP1A1;PPARG;SLC8A1;CYP1A2 GO:0034097| response to cytokine stimulus PTGS2;SPARC;AANAT GO:0007155| cell adhesion CIB1;CYP1B1;NRXN1 GO:0045087| innate immune response PPARG;S100B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;CALR GO:0042311| vasodilation CASR;GPX1 GO:0001822| kidney development PKD1L3;CAT;RGN GO:0086015| CACNA1G GO:0043066| negative regulation of apoptotic process CIB1;ALB;GPX1;CAT;HMGCR;PTGS2;TPT1;SOD1;RGN GO:0035722| interleukin-12-mediated signaling pathway CANX;SOD1 GO:0002576| platelet degranulation CALM1;SPARC;SOD1;ALB GO:0070207| protein homotrimerization TRPM8;PKD2L1 GO:0007626| locomotory behavior CALB1;OPRM1;SOD1 GO:0008284| positive regulation of cell proliferation CIB1;CALR;CASR;S100A13;CHRNA7;S100B;HTR1A;HTR2A;PTGS2;HMGCR GO:0010045| response to nickel cation CACNA1G GO:0009615| response to virus TPT1;CYP1A1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;SLC8A1;RYR3 GO:0070509| calcium ion import TRPV4;CACNA1I;CACNA1G;SLC8A1;CACNA1D;CASR;CACNA1H;CACNB2 GO:0007269| neurotransmitter secretion NAAA;NRXN1 GO:0030317| sperm motility CACNA1I;CATSPER1 GO:0071333| cellular response to glucose stimulus CASR;SLC29A1 GO:0030324| lung development SPARC;CYP1A2 GO:0086016| CACNA1G GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;CASR GO:0007614| short-term memory CHRNA7;CALB1 GO:0007611| learning or memory CNR1;CHRNA7;S100B;CALB1 GO:0071318| cellular response to ATP TRPV1;RYR3;CIB2;SOD1;PTGS2 GO:0042127| regulation of cell proliferation CIB1;PTGS2;PTGS1;SPARC GO:0042060| wound healing SPARC;OPRM1;ALOX15 GO:0007612| learning PTGS2;NRXN1;VDAC1 GO:0001508| regulation of action potential SRI;CACNA1G;GLRA1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;SPARC;CYP1A1;IDO1 GO:0016525| negative regulation of angiogenesis PPARG;SPARC GO:0071404| cellular response to low-density lipoprotein particle stimulus CASR;PPARG GO:0032342| aldosterone biosynthetic process CACNA1H GO:0007517| muscle organ development SRI;CACNA1H GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;SLC8A1;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CALR;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;RGN GO:0065009| regulation of molecular function NRXN1;TRPV1 GO:0007165| signal transduction S100A6;CHRNA7;CASR;SPARC;SRI;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1G;CACNA1I;CACNA1H GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0032870| cellular response to hormone stimulus CACNA1H GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;CASR GO:1904645| CHRNA7;CACNA1A GO:0043010| camera-type eye development FBN2;CACNA1C;CYP1A1 GO:0034765| regulation of ion transmembrane transport CACNB1;CACNA1F;CACNA1I;CACNA1A;CACNB3;CACNA1E;CACNA1S;CATSPER1;CACNA1G;CACNA1C;CACNB4;CACNA1D;CACNB2;CACNA1H GO:0070588| calcium ion transmembrane transport CACNA1F;RYR2;TRPV1;CACNA1I;TRPV4;CACNA1A;TRPM8;CACNB1;CACNA1E;RYR3;TRPV5;CACNA1S;CATSPER1;PKD2L1;CACNA1G;TRPA1;CACNB3;TRPV6;CACNA1C;NCS1;RYR1;TRPV2;CACNB4;SLC8A1;CACNA1D;CHRNA7;PKD1L3;TRPV3;CACNA1H;OPRM1;CACNB2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway CASR;OPRM1;OPRD1 GO:0007601| visual perception GLRA1;CRYZ;CACNA1F;GLRB;CYP1B1;CACNB2 GO:0007520| myoblast fusion CACNA1H GO:0007613| memory S100B;CHRNA7;PTGS2;CNR1;HTR2A GO:0050796| regulation of insulin secretion CACNA1E;CACNA1A;CNR1;CACNA1C;CACNA1D GO:0007204| elevation of cytosolic calcium ion concentration CIB2;TRPV1;TRPV4;CACNA1A;HTR2A;OPRM1;CACNA1C;SLC8A1 GO:0043434| response to peptide hormone stimulus TRPV1;SPARC GO:0051384| response to glucocorticoid stimulus PTGS2;S100B;SPARC GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CIB1;CYP1B1;PPARG GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0090280| positive regulation of calcium ion import TRPV2;CASR;TRPV3 GO:0006812| cation transport PKD2L1;TRPM8;PKD1L3 GO:0007584| response to nutrient CNR1;HMGCR;SLC8A1;PPARG GO:0086046| CACNA1G;CACNA1D GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G GO:0045740| positive regulation of DNA replication CALR;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation S100A6;PLA2G1B GO:0050896| response to stimulus TRPA1;CACNA1F;TRPM8 GO:0001895| retina homeostasis ALB;SOD1 GO:0033591| response to L-ascorbic acid CAT;SPARC GO:0006919| activation of caspase activity PDCD6;PPARG GO:0043267| negative regulation of potassium ion transport CASQ2;HTR2A GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1;CASR GO:0006811| ion transport GLRA3;CACNB2;TRPV3;CACNA1H;CHRNA7;PKD1L3;CACNA1C;RYR1;TRPV2;CACNB4;CACNA1D;SLC8A1;CACNB3;TRPA1;GLRA1;TRPV6;CACNA1E;RYR3;CATSPER1;CACNA1S;TRPV5;CACNA1G;PKD2L1;TRPM8;CACNB1;CACNA1F;RYR2;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;CACNA1A GO:0008283| cell proliferation HTR1A;S100B;GPX1;CYP1A1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CHP1;CYP1B1;CAT GO:0086045| CACNB2;CACNA1C;CACNA1G GO:0060078| regulation of postsynaptic membrane potential CHRNA7;SLC8A1 GO:1990090| TRPV1;CIB1 GO:0007507| heart development SRI;SPARC;CACNA1C;PPARG GO:0001503| ossification CASR;SPARC;ALOX15 GO:0002027| regulation of heart rate SLC8A1;CALM1;CALM3;RYR2;CASQ2;CACNA1G;CALM2 GO:0035556| intracellular signal transduction PLA2G1B;CAPS GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1;S100B GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CACNA1D;CNR1 GO:0042542| response to hydrogen peroxide TRPA1;SLC8A1;GPX1;CAT;SOD1 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;PKD2L1;SLC8A1;CACNA1H GO:0051592| response to calcium ion PEF1;CALM3;AANAT;CALM1;CASR;SPARC;CALM2;TRPV6;S100A16;PDCD6 GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1I;CACNA1G GO:0030431| sleep HTR2A;SLC29A1;CACNA1I GO:0001889| liver development CYP1A1;ACAT1;RGN GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT;SPARC GO:0001525| angiogenesis PTGS2;CYP1B1;CIB1;PDCD6 GO:0098662| CACNA1H GO:0071277| cellular response to calcium ion RYR1;RYR3;ALOX15 GO:0086091| CACNA1G;CACNB2;CACNA1D;CACNA1C GO:0008016| regulation of heart contraction SRI;CACNA1H GO:0086010| CACNA1H;CACNA1A;CACNA1I;CACNA1F;CACNA1G;CACNA1S;CATSPER1;CACNA1E GO:0051924| regulation of calcium ion transport SLC8A1;CASR;OPRD1;SRI GO:0006816| calcium ion transport CACNA1H;TRPV3;SRI;CACNB2;TPT1;CACNB4;TRPV2;CACNA1D;SLC8A1;CACNA1C;RYR1;CASR;CHRNA7;PKD1L3;CACNA1G;PKD2L1;CACNA1S;CATSPER1;TRPV5;CACNA1E;RYR3;TRPV6;CACNB3;TRPA1;TRPV1;CACNA1A;CACNA1I;TRPV4;CACNA1F;RYR2;CACNB1;TRPM8 GO:0051289| protein homotetramerization RYR1;CAT;TRPV1;TRPM8;RYR3;CRYZ;TRPA1 GO:0009408| response to heat TRPV2;TRPV3;SOD1;CASQ1;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CIB1;PLA2G1B;CAT GO:0034651| cortisol biosynthetic process CACNA1H GO:0001934| positive regulation of protein phosphorylation CHRNA7;CIB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;CIB1 GO:0007268| synaptic transmission CACNB4;NRXN1;OPRD1;OPRM1;GLRA3;HTR2A;CACNB2;GLRB;VDAC1;CACNB1;CACNA1E;CACNA1G;GLRA1;CACNB3 GO:0098703| TRPV1;TRPV6;TRPV5 GO:0071320| cellular response to cAMP AANAT;SLC8A1 18895:[DB14011 DB08358] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;SOD1;MAPKAPK2;PLA2G1B;MAPKAPK3 GO:0006691| leukotriene metabolic process ALOX5;MAPKAPK2;ALOX15;ABCC1 GO:0032496| response to lipopolysaccharide MAPKAPK2;IDO1;MAPKAPK3;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0034097| response to cytokine stimulus PTGS2;AANAT;MAPKAPK3;MAPKAPK2 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;MAPKAPK3;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0006954| inflammatory response MAPKAPK2;TRPV1;IDO1;ALOX15;PTGS2;CNR2;PTGS1;ALOX5 GO:0007166| cell surface receptor linked signaling pathway TRPV1;MAPKAPK3;TRPA1 18896:[DB14011 DB03333] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03333|(4-sulfamoyl-phenyl)-thiocarbamic acid O-(2-thiophen-3-yl-ethyl) ester CA2 common genes common pathways GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;CYP1A2;PTGS2;SOD1 18897:[DB14011 DB06838] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06838|methyl L-phenylalaninate F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PPARG;GPR18;F2 18898:[DB14011 DB03749] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03749|4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HSP90AA1 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0007165| signal transduction PPARG;HSP90AA1;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;TRPV3;SOD1 GO:0009409| response to cold HSP90AA1;PPARG;TRPA1;TRPM8 18899:[DB14011 DB05225] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05225|AM103 ALOX5AP common genes common pathways GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5AP;ALOX5 GO:0071277| cellular response to calcium ion ALOX5AP;ALOX15 GO:0006691| leukotriene metabolic process ALOX5;ALOX5AP;ALOX15;ABCC1 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5AP;GPX1;ALOX5 GO:0070207| protein homotrimerization ALOX5AP;TRPM8 GO:2001300| ALOX5;ALOX5AP GO:0043085| positive regulation of catalytic activity SOD1;ALOX5AP 18900:[DB14011 DB11948] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11948|Lapachone RBP3 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;RBP3;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 GO:0007601| visual perception RBP3;GLRA1;CRYZ;GLRB;CYP1B1 GO:0001523| retinoid metabolic process RBP3;NAPEPLD 18901:[DB14011 DB03672] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03672|9-N-Phenylmethylamino-Tacrine BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;BCHE GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;BCHE;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT 18902:[DB14011 DB07004] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07004|2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide S100B common genes common pathways GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;S100B;PTGS2;SOD1;CNR1 GO:0008283| cell proliferation CYP1A1;S100B;GPX1;HTR1A GO:0051384| response to glucocorticoid stimulus S100B;PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;S100B;CHRNA7 GO:0007611| learning or memory CNR1;CHRNA7;S100B GO:0008284| positive regulation of cell proliferation CHRNA7;S100B;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045087| innate immune response PPARG;S100B GO:0071456| cellular response to hypoxia SLC29A1;S100B;OPRD1;PTGS2 18903:[DB14011 DB04327] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;PPARG;CYP1A1;TRPA1;PTEN;SMPD1;ABCC1;ABCG2 GO:0046685| response to arsenic-containing substance PTEN;CYP1A1 GO:0010666| positive regulation of cardiac muscle cell apoptosis PTEN;HMGCR GO:0007611| learning or memory PTEN;CNR1;CHRNA7 GO:0043542| endothelial cell migration PTEN;CYP1B1 GO:0043066| negative regulation of apoptotic process PTEN;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0007626| locomotory behavior SOD1;OPRM1;PTEN GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;PTEN GO:0032228| regulation of synaptic transmission, GABAergic CNR1;PTEN GO:0006915| apoptotic process GPX1;PTEN;VDAC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade PTEN;TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;PTEN GO:0010033| response to organic substance PTEN;TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential PTEN;CHRNA7 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;PTEN GO:0007568| aging CAT;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;PTEN;CYP1A1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;PTEN GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;PTEN GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;PTEN GO:0001525| angiogenesis CYP1B1;PTEN;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PTEN;PPARG;TRPV1;CYP1B1;IDO1 GO:0071361| cellular response to ethanol PTEN;GLRA1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;CYP2C9;PPARG;PTEN;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B GO:1990090| TRPV1;PTEN GO:0007507| heart development PTEN;PPARG GO:0007399| nervous system development GLRB;SMPD1;PTEN GO:0007270| neuron-neuron synaptic transmission PTEN;VDAC1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTEN;ACAT1;AANAT;CYP1A2;PTGS2 GO:0008283| cell proliferation CYP1A1;PTEN;GPX1;HTR1A GO:0033555| multicellular organismal response to stress PTEN;IDO1 GO:0010043| response to zinc ion PTEN;AANAT GO:0030336| negative regulation of cell migration CYP1B1;PTEN GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTEN;OPRM1;PTGS2 GO:0014823| response to activity CAT;PTEN GO:0007584| response to nutrient PPARG;PTEN;CNR1;HMGCR GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7;PTEN GO:0032869| cellular response to insulin stimulus PTEN;PPARG;PLA2G1B 18904:[DB14011 DB03206] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03206|Duvoglustat MAN1B1;xylA common genes common pathways GO:0008152| metabolic process ACAT1;MAN1B1;SMPD1 18905:[DB14011 DB03389] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03389|alpha-D-Xylopyranose LCT common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;LCT 18906:[DB14011 DB08048] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08048|4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL ESR1;NCOA2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV1;TRPV4 GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CYP1A1;HMGCR;CNR1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;ESR1;HTR1A;GPR55;CHRNA7 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0048511| rhythmic process AANAT;PPARG;NCOA2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TRPV4;TRPV1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;PLA2G1B;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG 18907:[DB14011 DB08688] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08688|undecan-2-one ACOT13 common genes common pathways GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPV1;TRPM8;ACOT13;CAT 18908:[DB14011 DB03081] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03081|Crc200 (Chiron-Behring) PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 18909:[DB14011 DB06880] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 18910:[DB14011 DB04263] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04263|Geneticin ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;ODC1;CHRNA7 GO:0009615| response to virus CYP1A1;ODC1 GO:0001822| kidney development ODC1;CAT 18911:[DB14011 DB08693] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 18912:[DB14011 DB00127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;CASR GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;XDH;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;SMOX;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1 GO:0022900| electron transport chain GSR;IDO1;XDH;CYP1A2 GO:0009615| response to virus CYP1A1;ODC1 GO:0008284| positive regulation of cell proliferation ODC1;CHRNA7;CASR;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;PLA2G1B GO:0001822| kidney development ODC1;CAT GO:0042311| vasodilation CASR;GPX1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;CASR GO:0002024| diet induced thermogenesis ADRB2;TRPV1;TRPV4;ADRB1 GO:0070509| calcium ion import CACNA1G;TRPV4;CACNA1I;CACNA1H;CASR GO:0071333| cellular response to glucose stimulus SLC29A1;CASR GO:0042127| regulation of cell proliferation PTGS1;PTGS2;SAT1 GO:0010628| positive regulation of gene expression TRPV4;CASR GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;SLC22A1;TRPA1;TRPV2;CACNA1H;SLC22A4;TRPV3 GO:0006915| apoptotic process VDAC1;CASR;GPX1 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;SLC22A4;GLRB;TRPV1;GLRA1;TRPA1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;HTR2A;GPR12;CHRNA7;CASR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;CASR GO:0007635| chemosensory behavior TRPV1;CASR GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;ADRB1;OPRD1;OPRM1;CNR2;ADRB2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CASR GO:0007595| lactation XDH;SLC29A1 GO:0051924| regulation of calcium ion transport OPRD1;CASR GO:0006816| calcium ion transport TRPV2;CHRNA7;CASR;TRPV3;CACNA1H;TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;TRPA1 GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0010629| negative regulation of gene expression XDH;OPRD1 GO:0001503| ossification CASR;ALOX15 GO:0001659| temperature homeostasis ADRB1;TRPV1;GPX1;HTR2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0009409| response to cold ADRB2;TRPA1;PPARG;TRPM8;ADRB1 GO:0050873| brown fat cell differentiation ADRB1;ADRB2;PTGS2 GO:0001525| angiogenesis SAT1;PTGS2;CYP1B1 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPA1;TRPV1 GO:0051592| response to calcium ion AANAT;CASR GO:0090280| positive regulation of calcium ion import TRPV3;CASR;TRPV2 GO:0006812| cation transport SLC22A1;TRPM8 GO:0006855| drug transmembrane transport SLC22A1;ABCC1;ABCG2 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;SLC22A4;TRPV3;GLRA3;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;SLC22A1;GLRA1;TRPA1 GO:0006919| activation of caspase activity PPARG;XDH GO:0014070| response to organic cyclic compound CASR;AANAT;ACAT1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;ADRB1;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;ADRB2;CASR;CHRNA7 GO:0006641| triglyceride metabolic process SLC22A4;GPX1;CAT GO:0045453| bone resorption GPR55;ADRB2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;CASR GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;CASR GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 18913:[DB14011 DB06420] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06420|Annamycin TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TOP2A GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0043065| positive regulation of apoptotic process SMPD1;TOP2A;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG 18914:[DB14011 DB07382] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways GO:0034976| response to endoplasmic reticulum stress ALOX15;ERN1 GO:0006351| transcription, DNA-dependent PPARG;ERN1 GO:0008152| metabolic process ERN1;SMPD1;ACAT1 GO:0006915| apoptotic process ERN1;VDAC1;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ERN1 GO:0071333| cellular response to glucose stimulus SLC29A1;ERN1 18915:[DB14011 DB01712] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways GO:1902991| FKBP1A;CHRNA7 GO:0031000| response to caffeine FKBP1A;PPARG GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;TRPV1;FKBP1A GO:0006936| muscle contraction CACNA1H;FKBP1A;GLRA1 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;FKBP1A;TRPV1;CACNA1I;TRPV4;TRPV3;OPRM1;CACNA1H;CHRNA7;TRPV2 18916:[DB14011 DB00547] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00547|Desoximetasone NR3C1 common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;NR3C1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PLA2G1B;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG 18917:[DB14011 DB00868] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00868|Benzonatate SCN5A common genes common pathways GO:0086015| SCN5A;CACNA1G GO:0086016| SCN5A;CACNA1G GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2;SCN5A GO:0086002| SCN5A;CACNA1G GO:0002027| regulation of heart rate CACNA1G;SCN5A GO:0071277| cellular response to calcium ion SCN5A;ALOX15 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0086091| CACNA1G;SCN5A GO:0086010| SCN5A;CACNA1H;CACNA1I;CACNA1G GO:0034765| regulation of ion transmembrane transport CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0086046| SCN5A;CACNA1G GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN5A GO:0086045| SCN5A;CACNA1G GO:0006811| ion transport TRPV2;CHRNA7;SCN5A;TRPV3;CACNA1H;GLRA3;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 18918:[DB14011 DB03844] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03844|N-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;TRPA1;CA2 GO:0001822| kidney development CAT;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 18919:[DB14011 DB07795] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07795|Fisetin CDK6 common genes common pathways GO:0045786| negative regulation of cell cycle CDK6;PTGS2 GO:0009615| response to virus CYP1A1;CDK6 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CDK6 GO:0010468| regulation of gene expression CDK6;CYP1A2 GO:0007165| signal transduction GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;CDK6;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;CDK6;OPRM1;PTGS2 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;CDK6 18920:[DB14011 DB03096] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03096|N-Aminoethylmorpholine CTSD common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;CTSD 18921:[DB14011 DB09103] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09103|Ancestim KIT common genes common pathways GO:0008542| visual learning KIT;HMGCR GO:0048565| digestive tract development CYP1A1;KIT GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;CNR2;PTGS2;KIT;ALOX5;PTGS1 GO:0030217| T cell differentiation KIT;GPR18 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;KIT GO:0009314| response to radiation CAT;KIT;PTGS2;OPRM1 GO:0035556| intracellular signal transduction KIT;PLA2G1B GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;PPARG GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7;KIT GO:0051897| positive regulation of protein kinase B signaling cascade KIT;GPX1 GO:0060326| cell chemotaxis KIT;ABCC1 GO:0046427| positive regulation of JAK-STAT cascade KIT;CYP1B1 GO:0008284| positive regulation of cell proliferation KIT;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0042127| regulation of cell proliferation PTGS1;KIT;PTGS2 GO:0043406| positive regulation of MAP kinase activity KIT;HTR2A GO:0010628| positive regulation of gene expression TRPV4;KIT GO:0007283| spermatogenesis KIT;CNR1;SOD1 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7;KIT GO:0001541| ovarian follicle development KIT;SOD1 GO:0031532| actin cytoskeleton reorganization TRPV4;KIT GO:0046686| response to cadmium ion CAT;KIT GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KIT;CAT GO:0006687| glycosphingolipid metabolic process KIT;SMPD1 18922:[DB14011 DB12731] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12731|Daporinad NAMPT common genes common pathways GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;NAMPT;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway NAMPT;PTGS2 GO:0060612| adipose tissue development NAMPT;ACAT1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;NAMPT;PPARG;CYP1A1;TRPA1 GO:0007565| female pregnancy IDO1;NAMPT GO:0048511| rhythmic process PPARG;NAMPT;AANAT GO:0008284| positive regulation of cell proliferation NAMPT;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NAMPT;PLA2G1B;PPARG GO:0007623| circadian rhythm AANAT;NAMPT GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;NAMPT 18923:[DB14011 DB07201] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0006810| transport TRPV2;TTR;ABCC1;CACNA1I;TRPV1;ABCG2 18924:[DB14011 DB05446] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05446|LJP 1082 APOH common genes common pathways GO:0002576| platelet degranulation SOD1;APOH GO:0016525| negative regulation of angiogenesis APOH;PPARG GO:0006641| triglyceride metabolic process CAT;GPX1;APOH 18925:[DB14011 DB04573] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR2;ESR1 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0042493| response to drug ABCB1;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0006810| transport ABCC1;ABCB1;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;CACNA1I;ABCB1;TRPV4;TRPM8;ABCG2;SLCO1A2;TRPV3;CACNA1H;TRPV2 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0007165| signal transduction ESR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;ESR1;OPRD1;OPRM1;CNR2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ESR1;HTR2A;OPRM1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0006811| ion transport GLRA3;CACNA1H;SLCO1A2;TRPV3;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 18926:[DB14011 DB06963] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0008283| cell proliferation CYP1A1;PLK1;GPX1;HTR1A GO:0043066| negative regulation of apoptotic process CAT;PLK1;GPX1;SOD1;HMGCR;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;PPARG;TRPV1;TRPV4 18927:[DB14011 DB00893] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0010942| positive regulation of cell death HBB;HBA1;PTGS2 GO:0006955| immune response FTH1;OPRD1;CNR2 GO:0006879| cellular iron ion homeostasis ABCG2;FTH1;FTL;SOD1;TF GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;TRPA1;HBB;HBA1 GO:0051291| protein heterooligomerization GLRA1;HBB;HBA1;GLRB GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;HBB GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;FTH1;PTGS2;OPRM1 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;TF;CACNA1H;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPA1;GLRA1;CACNA1G GO:0001895| retina homeostasis SOD1;TF GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;FTH1;GPX1;ALOX5;PTGS1;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0002576| platelet degranulation TF;SOD1 GO:0043312| neutrophil degranulation HBB;ALOX5;FTH1;FTL;CAT GO:0042744| hydrogen peroxide catabolic process HBA1;HBB;GPX1;CAT GO:0098869| PTGS2;CAT;GPX1;PTGS1;HBB;HBA1;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;HBB;TRPV1 18928:[DB14011 DB00128] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process CAT;ASPH;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0022900| electron transport chain ASPH;CYP1A2;IDO1;GSR GO:0045893| positive regulation of transcription, DNA-dependent ASPH;PPARG GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LYZ GO:0042594| response to starvation ACAT1;ADSSL1;CAD;PPARG GO:0043312| neutrophil degranulation CAT;ALOX5;LYZ GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;ASNS;SOD1 GO:0009612| response to mechanical stimulus ASNS;TRPV4;PPARG GO:0007623| circadian rhythm ASS1;AANAT GO:0010524| positive regulation of calcium ion transport into cytosol ASPH;PLA2G1B GO:0031000| response to caffeine PPARG;CAD GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;ASPA GO:0009416| response to light stimulus ASNS;AANAT GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;SLC25A12;SLC25A13;SLC16A10;TRPV3;CACNA1H GO:0043200| response to amino acid stimulus ASNS;GLRA3;GLRB GO:0034220| ion transmembrane transport GLRA3;ASPH;CHRNA7;TRPA1;GLRA1;TRPV1;GLRB GO:0017144| drug metabolic process CYP2D6;CYP2C19;CAD;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;ASS1 GO:0006936| muscle contraction GLRA1;CACNA1H;ASPH GO:0031100| organ regeneration CAD;PPARG GO:0002376| immune system process IDO1;ADSSL1;ADSS GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC1A1 GO:1902476| GLRA3;GLRA1;GLRB;SLC1A1 GO:0007595| lactation SLC29A1;CAD GO:0016032| viral reproduction HTR2A;VDAC1;ACY3 GO:0014047| glutamate secretion SLC1A1;TRPV1 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;IDO1;ALOX15;LYZ;TRPV1 GO:0007565| female pregnancy CAD;IDO1 GO:0031667| response to nutrient levels ASNS;SOD1 GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;SLC1A1;OPRM1;OPRD1;HTR2A;GLRA3 GO:0007507| heart development CAD;PPARG GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A5;CYP1B1;ACY3;CYP2C9;ACY1;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0008152| metabolic process ACAT1;ACY1;PAICS;LYZ;CAD;ACY3;ASPA;SMPD1 GO:0051592| response to calcium ion SLC25A12;AANAT;SLC25A13 GO:0001889| liver development CAD;CYP1A1;ACAT1;ASNS GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CAT;GOT2 GO:0071277| cellular response to calcium ion ALOX15;ASPH GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;ASPH;PTGS2;OPRM1 GO:0001895| retina homeostasis SOD1;LYZ GO:0032868| response to insulin stimulus TRPV4;CAD;CAT;AANAT GO:0009636| response to toxin CAT;GPX1;ASNS;CYP1B1;CYP1A1 GO:0006811| ion transport SLC1A1;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3 GO:0045333| cellular respiration CYP1A2;SLC25A13 GO:0032870| cellular response to hormone stimulus CACNA1H;ASNS GO:0070588| calcium ion transmembrane transport ASPH;TRPV2;CHRNA7;OPRM1;CACNA1H;TRPV3;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;GOT1 GO:0051384| response to glucocorticoid stimulus GOT1;PTGS2 18929:[DB14011 DB06321] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06321|R-348 JAK3 common genes common pathways GO:0065009| regulation of molecular function TRPV1;JAK3 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS1;ALOX5;CNR2;PTGS2;JAK3 GO:0032693| negative regulation of interleukin-10 production IDO1;JAK3 GO:0035556| intracellular signal transduction PLA2G1B;JAK3 GO:0002376| immune system process IDO1;JAK3 GO:0045087| innate immune response JAK3;PPARG 18930:[DB14011 DB02281] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02281|Formycin MTAP common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;MTAP GO:0035722| interleukin-12-mediated signaling pathway MTAP;SOD1 18931:[DB14011 DB02598] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0051384| response to glucocorticoid stimulus PAM;PTGS2 GO:0008152| metabolic process ACAT1;SMPD1;PAM GO:0007507| heart development PPARG;PAM GO:0006357| regulation of transcription from RNA polymerase II promoter PAM;PPARG GO:0007595| lactation PAM;SLC29A1 GO:0009268| response to pH PAM;TRPV1 GO:0051260| protein homooligomerization GLRA1;PAM;GLRA3;ACAT1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;PAM GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;PAM GO:0046688| response to copper ion PAM;AANAT;SOD1 GO:0009404| toxin metabolic process CYP1A1;PAM;CYP1B1;CYP1A2 GO:0060135| maternal process involved in female pregnancy CNR1;PAM GO:0042493| response to drug PAM;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;PAM;CRYZ;CYP1A1;CYP2C9;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 18932:[DB14011 DB05209] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05209|SYM001 RHD common genes common pathways 18933:[DB14011 DB04437] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04437|Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline FABP4 common genes common pathways GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0050872| white fat cell differentiation FABP4;PPARG GO:0050729| positive regulation of inflammatory response TRPV4;FABP4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;FABP4 GO:0071356| cellular response to tumor necrosis factor TRPV1;FABP4 18934:[DB14011 DB14639] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14639|Boldenone undecylenate AR common genes common pathways GO:0006810| transport AR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0010468| regulation of gene expression AR;CYP1A2 GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0008284| positive regulation of cell proliferation AR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;TRPV1;TRPV4;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;AR;CHRNA7 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;AR GO:0007548| sex differentiation CYP17A1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT 18935:[DB14011 DB07231] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07231|N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE CTSB common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;CTSB GO:0030855| epithelial cell differentiation VDAC1;CTSB;PPARG GO:0046697| decidualization CTSB;PTGS2 GO:0046718| entry of virus into host cell CTSB;HTR2A 18936:[DB14011 DB06802] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06802|Nepafenac PTGS1;PTGS2 common genes PTGS1;PTGS2 common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;GPX1;NAAA;PTGS1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;TRPA1;TRPV1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| GSR;PTGS2;CAT;GPX1;PTGS1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT;CYP1A1 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;GPX1;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0071284| cellular response to lead ion PTGS2 18937:[DB14011 DB03093] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03093|8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HSP90AA1;PTGS2;OPRM1 GO:0009408| response to heat SOD1;TRPV3;TRPV2;HSP90AA1;TRPV1 GO:0009409| response to cold TRPM8;PPARG;HSP90AA1;TRPA1 GO:0007165| signal transduction SMPD1;GPR18;HSP90AA1;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7 18938:[DB14011 DB00797] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug ADRA1A;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;HTR2A;OPRM1;HRH1;OPRD1 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;ADRA2A GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ADRA1A;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0000187| activation of MAPK activity ADRA2B;SOD1;CHRNA7;PLA2G1B GO:0006915| apoptotic process GPX1;VDAC1;ADRA1A GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR2;CNR1;HRH2 GO:0007202| activation of phospholipase C activity ADRA1A;HTR2A;GPR55 GO:0007568| aging CYP1A1;ADRA1A;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;ADRA2A;PPARG;GPR18;OPRM1;CNR2;OPRD1;HRH1;GPR55;HTR1A;ADRA2C;ADRA2B;GPR12;CNR1;HTR2A;HRH2 GO:0042593| glucose homeostasis CNR1;PPARG;ADRA2A;TRPV4 GO:0007565| female pregnancy ADRA2C;ADRA2B;IDO1 GO:0048565| digestive tract development CYP1A1;HRH2 GO:0008542| visual learning HRH2;HRH1;HMGCR GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;CNR2;PTGS2;HRH1 GO:0006955| immune response CNR2;OPRD1;HRH2 GO:0035556| intracellular signal transduction PLA2G1B;ADRA1A GO:0045777| positive regulation of blood pressure CNR1;ADRA2B GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADRA2C GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;ADRA1A;OPRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0050796| regulation of insulin secretion ADRA2A;ADRA2C;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;ADRA1A;TRPV1 GO:0007613| memory CHRNA7;HTR2A;CNR1;HRH2;HRH1;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A GO:0009725| response to hormone stimulus ADRA1A;ACAT1 GO:0007165| signal transduction CACNA1I;ADRA1A;PLA2G1B;ADRA2A;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;HRH1;OPRD1;ADRA2C;HTR1A;GPR55;HRH2;HTR2A;GPR12;CNR1;ADRA2B GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A;HRH2;ADRA2C;ADRA1A GO:0001819| positive regulation of cytokine production ADRA2A;SOD1 GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H 18939:[DB14011 DB00345] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes ABCC1 common pathways GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCG2;ABCC2;CACNA1I;TRPV1;ABCC1;TRPV2 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;SLC16A1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0006979| response to oxidative stress ABCC2;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0034220| ion transmembrane transport TRPA1;GLRA1;GLRB;TRPV1;SLC22A4;GLRA3;CHRNA7 GO:0055085| transmembrane transport TRPA1;CACNA1G;SLC22A6;ABCC1;ABCG2;SLC22A2;TRPM8;ABCC2;VDAC1;TRPV4;CACNA1I;TRPV1;SLC22A8;SLC22A5;SLCO1B1;CACNA1H;SLC22A4;SLCO1A2;TRPV3;SLCO3A1;SLC16A1;SLC22A7;SLC22A11;TRPV2 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;CYP1A1;ABCC2;IDO1 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2;ABCC2 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 GO:0099133| ABCC1;ABCC2 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1A1;CYP1B1 GO:0032094| response to food SLC16A1;OPRM1;CYP1A1 GO:0060326| cell chemotaxis ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0006641| triglyceride metabolic process CAT;GPX1;SLC22A4 GO:0006811| ion transport GLRA3;SLC22A5;SLC22A8;SLCO1B1;SLC22A4;SLCO3A1;TRPV3;SLCO1A2;CACNA1H;SLC22A11;CHRNA7;SLC22A7;TRPV2;TRPA1;GLRA1;CACNA1G;SLC22A2;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0006855| drug transmembrane transport ABCC2;SLC22A2;ABCG2;ABCC1;SLC22A5 GO:0006812| cation transport SLC22A2;TRPM8 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0098656| SLC22A7;SLC22A8;VDAC1;SLC22A6 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;SLC16A1;NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0034775| glutathione transmembrane transport ABCC1 GO:0007565| female pregnancy ABCC2;IDO1 GO:0046415| urate metabolic process SLC22A11;ABCG2 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;ABCC2 18940:[DB14011 DB02783] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways GO:0045471| response to ethanol CAT;SOD1;CNR1;OPRM1;HMGCR;GOT2 18941:[DB14011 DB08046] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08046|2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;SOD1;CYP1A2;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 18942:[DB14011 DB07628] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07628|6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one PKM common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;PKM GO:0031100| organ regeneration PPARG;PKM GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1;PKM GO:0001666| response to hypoxia CAT;PKM;CHRNA7;CYP1A1 GO:0001889| liver development CYP1A1;PKM;ACAT1 GO:0043403| skeletal muscle tissue regeneration PKM;GPX1 GO:0008152| metabolic process SMPD1;PKM;ACAT1 GO:0051289| protein homotetramerization CAT;PKM;TRPA1;CRYZ;TRPM8;TRPV1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PKM GO:0032868| response to insulin stimulus PKM;AANAT;CAT;TRPV4 GO:0007584| response to nutrient PPARG;CNR1;HMGCR;PKM 18943:[DB14011 DB07895] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07895|ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID FNTB;FNTA common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;FNTB;PTGS1 18944:[DB14011 DB06444] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06444|Dexanabinol TNF common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TNF;PTGS2;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;TNF;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;TNF GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TNF;TRPA1;CYP1A1;PPARG GO:0010628| positive regulation of gene expression TNF;TRPV4 GO:0071230| cellular response to amino acid stimulus TNF;GLRA1 GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0042127| regulation of cell proliferation TNF;PTGS2;PTGS1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;TNF GO:0009615| response to virus TNF;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TNF;PPARG GO:0050830| defense response to Gram-positive bacterium TNF;PLA2G1B GO:0045893| positive regulation of transcription, DNA-dependent TNF;PPARG GO:0071407| cellular response to organic cyclic compound CYP1B1;TNF;CYP1A1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;TNF GO:0050796| regulation of insulin secretion CNR1;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;TNF GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0006919| activation of caspase activity PPARG;TNF GO:0031622| positive regulation of fever generation TNF;CNR1;PTGS2 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;TNF;PPARG GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0010629| negative regulation of gene expression TNF;OPRD1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;TNF;PTGS1;ALOX5;CNR2;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;TNF;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0006955| immune response OPRD1;CNR2;TNF 18945:[DB14011 DB05595] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05595|Farletuzumab FOLR1 common genes common pathways GO:0048678| response to axon injury SOD1;FOLR1 18946:[DB14011 DB08174] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08174|5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 18947:[DB14011 DB06103] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06103|VX-148 IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP2C9;CYP1A1;IMPDH1;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;IMPDH2;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:0007623| circadian rhythm IMPDH2;AANAT GO:0043312| neutrophil degranulation IMPDH1;IMPDH2;ALOX5;CAT GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPV1;TRPM8;IMPDH2;CAT 18948:[DB14011 DB00061] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00061|Pegademase bovine GRB2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;GRB2 GO:0045087| innate immune response PPARG;GRB2 GO:0030838| positive regulation of actin filament polymerization ALOX15;GRB2 GO:0042127| regulation of cell proliferation GRB2;PTGS2;PTGS1 GO:0007568| aging GRB2;CYP1A1;CAT;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2 GO:0016032| viral reproduction VDAC1;GRB2;HTR2A GO:0051291| protein heterooligomerization GLRB;GRB2;GLRA1 GO:0065009| regulation of molecular function GRB2;TRPV1 18949:[DB14011 DB07002] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0001666| response to hypoxia NOS2;CYP1A1;CHRNA7;CAT GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;IDO1;NOS2;CYP1A1 GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0007623| circadian rhythm NOS2;AANAT GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP2C9;CYP1A1;CRYZ;NOS2;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1 GO:0006801| superoxide metabolic process NOS2;SOD1 18950:[DB14011 DB01113] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01113|Papaverine PDE4B;PDE10A common genes common pathways GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B GO:0007186| G-protein coupled receptor signaling pathway PDE4B;GPR18;PPARG;PDE10A;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0008152| metabolic process SMPD1;ACAT1;PDE10A GO:0007165| signal transduction GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PDE10A;CHRNA7;PPARG;GPR18;SMPD1;PDE4B;CACNA1I;PLA2G1B 18951:[DB14011 DB07364] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;GLRB;VDAC1;GLRA1;CDK5;CACNA1G GO:0008542| visual learning CDK5;HMGCR GO:0019233| sensory perception of pain OPRD1;CNR2;PTGS2;OPRM1;HTR2A;CNR1;TRPA1;CDK5;TRPV1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CDK5 GO:0007399| nervous system development GLRB;CDK5;SMPD1 GO:0048148| behavioral response to cocaine CDK5;HTR2A GO:0008283| cell proliferation HTR1A;CDK5R1;GPX1;CDK5;CYP1A1 GO:0051966| regulation of synaptic transmission, glutamatergic CNR1;CDK5 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CACNA1G;CDK5;CACNA1I GO:0007420| brain development CDK5R1;ACAT1 GO:0007413| axonal fasciculation CDK5R1;CNR1 GO:0070509| calcium ion import TRPV4;CACNA1I;CDK5;CACNA1G;CACNA1H GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1;CDK5 GO:0045786| negative regulation of cell cycle PTGS2;CDK5 GO:0006915| apoptotic process GPX1;CDK5;VDAC1 GO:0042220| response to cocaine CNR1;OPRM1;CDK5;SMPD1 GO:0045892| negative regulation of transcription, DNA-dependent CDK5R1;CDK5;PPARG GO:0048511| rhythmic process CDK5R1;AANAT;CDK5;PPARG GO:0009611| response to wounding CDK5;CYP1A1;GPX1 18952:[DB14011 DB14072] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14072|Reversin 121 ABCB1 common genes common pathways GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV1;VDAC1;ABCB1;TRPV4;CACNA1I;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0006810| transport ABCC1;CACNA1I;ABCB1;TRPV1;ABCG2;TRPV2 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 18953:[DB14011 DB05758] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05758|CYT007-TNFQb TNF common genes common pathways GO:0006919| activation of caspase activity TNF;PPARG GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0050796| regulation of insulin secretion CNR1;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0006955| immune response OPRD1;CNR2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;PLA2G1B;CAT GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TNF;IDO1;ALOX15;TRPV1 GO:0010629| negative regulation of gene expression TNF;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;TNF;PPARG;CYP1B1;TRPV1;IDO1 GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation TNF;PTGS2;CNR1 GO:0010628| positive regulation of gene expression TRPV4;TNF GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TNF;TRPA1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TNF;TRPV4;ALOX15 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TNF;PTGS2;OPRM1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0071407| cellular response to organic cyclic compound CYP1B1;TNF;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0009615| response to virus TNF;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;TNF GO:0042127| regulation of cell proliferation TNF;PTGS2;PTGS1 GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0071230| cellular response to amino acid stimulus GLRA1;TNF 18954:[DB14011 DB07081] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia DPP4;CYP1A1;CHRNA7;CAT GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 18955:[DB14011 DB07683] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07683|N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine MMP12 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;MMP12 GO:0042060| wound healing MMP12;OPRM1;ALOX15 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;MMP12 18956:[DB14011 DB02681] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02681|2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium CKS1B common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CKS1B GO:0006355| regulation of transcription, DNA-dependent PPARG;CKS1B GO:0008283| cell proliferation CKS1B;CYP1A1;GPX1;HTR1A 18957:[DB14011 DB00205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00205|Pyrimethamine DHFR;HEXB;CYP2C8;SLC47A1;SLC47A2 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C8;CYP3A5;ALOX15;CYP17A1;DHFR;CRYZ;CYP2C9;CYP1A1 GO:0050905| neuromuscular process GLRB;GLRA1;HEXB GO:0043312| neutrophil degranulation ALOX5;CAT;HEXB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C8;CYP2C19 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;HEXB GO:0007626| locomotory behavior SOD1;OPRM1;HEXB GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;CACNA1G;ABCC1;SLC47A2;SLC47A1;TRPV2;CACNA1H;TRPV3 GO:0002933| CYP1A1;CYP2C8;CYP3A5;CYP3A4;CYP3A7 GO:0007605| sensory perception of sound SOD1;GPX1;HEXB GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0006874| cellular calcium ion homeostasis CHRNA7;HEXB;GPR12;HTR2A;TRPM8;TRPV4 GO:0006687| glycosphingolipid metabolic process SMPD1;HEXB GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C8;CYP2C19;CYP2D6 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2C9 GO:0008152| metabolic process ACAT1;HEXB;SMPD1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC47A1;SLC47A2 GO:0097267| CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C8;CYP2C9 18958:[DB14011 DB06495] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06495|Onercept TNF common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2;HMGCR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0009615| response to virus CYP1A1;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TNF;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;TNF;PPARG GO:0042127| regulation of cell proliferation TNF;PTGS1;PTGS2 GO:0071230| cellular response to amino acid stimulus TNF;GLRA1 GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;TNF GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0010033| response to organic substance TNF;TRPA1;PPARG;CYP1A1;SOD1;CYP1A2;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;TNF;ALOX15;TRPV4 GO:0000187| activation of MAPK activity PLA2G1B;TNF;CHRNA7;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TNF;PTGS2;OPRM1 GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;IDO1;ALOX15;TRPV1;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0006955| immune response TNF;CNR2;OPRD1 GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;TNF;CYP1B1;TRPV1;IDO1 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0031622| positive regulation of fever generation TNF;CNR1;PTGS2 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0006919| activation of caspase activity PPARG;TNF GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2;OPRD1 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0050796| regulation of insulin secretion TNF;CNR1 18959:[DB14011 DB01897] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways GO:0006631| fatty acid metabolic process PTGS1;HPGDS;PTGS2;ALOX15 GO:0007626| locomotory behavior HPGDS;OPRM1;SOD1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1;HPGDS GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;HPGDS GO:0006633| fatty acid biosynthetic process PLA2G1B;HPGDS;PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;HPGDS;PTGS2 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;HPGDS;GPX1;NAAA;PTGS1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B GO:0006693| prostaglandin metabolic process PTGS1;HPGDS;PTGS2 18960:[DB14011 DB04387] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04387|1-Hydroxy-2-Amino-3-Cyclohexylpropane REN common genes common pathways GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;REN GO:0048469| cell maturation PPARG;REN GO:0051591| response to cAMP AANAT;REN GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;REN;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide REN;CYP1A1;IDO1;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;REN GO:0001822| kidney development CAT;REN GO:0042493| response to drug REN;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT 18961:[DB14011 DB04844] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes CYP2D6 common pathways GO:0009791| post-embryonic development CYP1A2;SLC18A2 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;DRD2;PPARG GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0009636| response to toxin CAT;GPX1;SLC18A2;DRD2;CYP1B1;CYP1A1 GO:0014854| response to inactivity CAT;DRD2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:1900273| CHRNA7;DRD2 GO:0050482| arachidonic acid secretion PLA2G1B;DRD2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0007165| signal transduction PLA2G1B;CACNA1I;DRD2;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0001975| response to amphetamine CNR2;SLC18A2;SOD1;DRD2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0001964| startle response GLRA1;DRD2;GLRB GO:0008542| visual learning HMGCR;DRD2 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0007268| synaptic transmission GLRA1;CACNA1G;VDAC1;GLRB;SLC18A2;HTR2A;GLRA3;OPRM1;OPRD1 GO:0019371| cyclooxygenase pathway CBR1;PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0048148| behavioral response to cocaine DRD2;HTR2A GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1;DRD2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;NAAA;GPX1;PTGS1 GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0051100| negative regulation of binding CYP2D6 GO:0048678| response to axon injury DRD2;SOD1 GO:0045776| negative regulation of blood pressure DRD2;CNR1 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;SOD1;CNR1;DRD2 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DRD2 GO:0014059| regulation of dopamine secretion DRD2;HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD2;GPR18;GPR55 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0009416| response to light stimulus DRD2;AANAT GO:0030855| epithelial cell differentiation CBR1;VDAC1;PPARG GO:0042220| response to cocaine SMPD1;DRD2;OPRM1;CNR1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1H;TRPV3;SLC18A2;TRPV2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;DRD2 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;TRPM8;TRPV4;DRD2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CBR1;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0051209| release of sequestered calcium ion into cytosol TRPV1;DRD2;TRPA1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;DRD2;PPARG;GPR18 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;DAGLA;CYP2D6 GO:0043278| response to morphine CNR1;OPRM1;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0035094| response to nicotine CHRNA7;CNR1;DRD2 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;DRD2 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;CBR1;CYP1A1;CYP2C9;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0007626| locomotory behavior DRD2;OPRM1;SLC18A2;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;DRD2 GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0007628| adult walking behavior GLRB;DRD2;GLRA1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0007269| neurotransmitter secretion NAAA;SLC18A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;DRD2;GLRA1 18962:[DB14011 DB08067] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways GO:0008631| induction of apoptosis by oxidative stress JAK2;CYP1B1;GPX1 GO:0043524| negative regulation of neuron apoptosis JAK2;SOD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;PPARG GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;JAK2;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response PTGS2;JAK2 GO:0035556| intracellular signal transduction PLA2G1B;JAK2 GO:0006919| activation of caspase activity JAK2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;JAK2;CYP1B1;OPRM1;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration JAK2;TRPV1;TRPV4;HTR2A;OPRM1 GO:0050729| positive regulation of inflammatory response JAK2;TRPV4 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;JAK2;CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0010811| positive regulation of cell-substrate adhesion ALOX15;JAK2 GO:0033194| response to hydroperoxide JAK2;GPX1 GO:0032496| response to lipopolysaccharide JAK2;CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0042127| regulation of cell proliferation JAK2;PTGS2;PTGS1 GO:0045087| innate immune response PPARG;JAK2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;JAK2 GO:0046677| response to antibiotic SOD1;JAK2;CYP1A1 GO:0035722| interleukin-12-mediated signaling pathway JAK2;SOD1 GO:0034612| response to tumor necrosis factor PTGS2;JAK2 GO:0006915| apoptotic process VDAC1;JAK2;GPX1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade JAK2;CAT GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG;JAK2 GO:0002376| immune system process JAK2;IDO1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;JAK2;PTGS2;OPRM1 GO:0043388| positive regulation of DNA binding PPARG;JAK2 GO:0006979| response to oxidative stress JAK2;PTGS2;SOD1;PTGS1;GPX1;CAT 18963:[DB14011 DB02342] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes CYP1A1;CYP1B1 common pathways GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CYP1A1 GO:0048514| blood vessel morphogenesis CYP1B1;HIF1A GO:0071456| cellular response to hypoxia OPRD1;PTGS2;HIF1A;SLC29A1 GO:0010468| regulation of gene expression HIF1A;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1 GO:0009611| response to wounding CYP1A1;GPX1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0010041| response to iron(III) ion CYP1A1 GO:0042574| retinal metabolic process CYP1B1 GO:0042593| glucose homeostasis TRPV4;PPARG;HIF1A;CNR1 GO:0045766| positive regulation of angiogenesis CYP1B1;HIF1A;CHRNA7 GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0046716| muscle cell homeostasis SOD1;HIF1A GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CHRNA7;CAT;HIF1A;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;HIF1A GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0043542| endothelial cell migration CYP1B1 GO:0030199| collagen fibril organization CYP1B1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0007614| short-term memory CHRNA7;COMT GO:0009812| flavonoid metabolic process CYP1A1 GO:0007612| learning COMT;VDAC1;PTGS2 GO:0042127| regulation of cell proliferation HIF1A;PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;IDO1;COMT;CYP1A1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0007155| cell adhesion CYP1B1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0032259| methylation COMT;CYP1A2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;HIF1A;SOD1;PTGS2;HMGCR GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0009615| response to virus CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HIF1A;PLA2G1B;PPARG GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 GO:0055114| oxidation-reduction process CYP19A1;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0032094| response to food OPRM1;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;CYP19A1 GO:0045893| positive regulation of transcription, DNA-dependent HIF1A;PPARG GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;COMT;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;HIF1A GO:0046685| response to arsenic-containing substance CYP1A1 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0048265| response to pain TRPV1;COMT;TRPA1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0008210| estrogen metabolic process CYP1B1;COMT GO:0061298| retina vasculature development in camera-type eye CYP1B1;HIF1A GO:0006694| steroid biosynthetic process CYP19A1;CYP17A1;HMGCR GO:0009308| amine metabolic process CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;CYP2D6;DAGLA;FAAH GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1 GO:0032502| developmental process CYP1A1;COMT GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:1900087| CYP1A1 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;HIF1A;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0043010| camera-type eye development CYP1A1 GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0009624| response to nematode CYP1A1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0002930| CYP1B1 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1;COMT GO:0051930| regulation of sensory perception of pain COMT;OPRM1;OPRD1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;HIF1A GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0046466| membrane lipid catabolic process CYP1B1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0043627| response to estrogen stimulus COMT;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1 GO:0030336| negative regulation of cell migration CYP1B1 GO:0017143| insecticide metabolic process CYP1A1 GO:0070988| demethylation CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0006351| transcription, DNA-dependent PPARG;HIF1A GO:0001525| angiogenesis HIF1A;PTGS2;CYP1B1 GO:0045821| positive regulation of glycolysis HIF1A;HTR2A GO:0009692| ethylene metabolic process CYP1A1 GO:0010575| positive regulation vascular endothelial growth factor production HIF1A;PTGS2;CYP1B1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0042572| retinol metabolic process CYP1B1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP19A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0007565| female pregnancy COMT;IDO1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0009635| response to herbicide CYP1A1 GO:0010629| negative regulation of gene expression OPRD1;HIF1A GO:0043524| negative regulation of neuron apoptosis SOD1;HIF1A GO:0008542| visual learning HIF1A;HMGCR GO:0006879| cellular iron ion homeostasis HIF1A;SOD1;ABCG2 GO:0048565| digestive tract development CYP1A1 GO:0007595| lactation HIF1A;SLC29A1 GO:0060137| maternal process involved in parturition CYP1A1 18964:[DB14011 DB14502] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0046686| response to cadmium ion SLC34A1;CAT GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;SLC34A2;CACNA1I;TRPV4;VDAC1;TRPV1;SLC20A1;TRPV3;CACNA1H;SLC20A2;SLC34A3;TRPV2 GO:0051260| protein homooligomerization GLRA1;SLC34A1;ACAT1;GLRA3 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;SLC34A1;CAT GO:0006810| transport SLC20A2;TRPV2;SLC20A1;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0033189| response to vitamin A PPARG;CYP1A1;SLC34A1;CAT GO:0042493| response to drug CAT;SLC34A1;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1 GO:0001822| kidney development SLC34A1;CAT GO:0010288| response to lead ion SLC34A1;CAT GO:0043627| response to estrogen stimulus SLC34A2;PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR;SLC34A1 GO:0006811| ion transport CHRNA7;SLC20A2;SLC34A3;TRPV2;SLC34A1;SLC20A1;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;SLC34A2;GLRA1;TRPA1;CACNA1G GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;SLC20A1;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0046718| entry of virus into host cell SLC20A2;HTR2A GO:0043434| response to peptide hormone stimulus SLC34A1;TRPV1 GO:0016032| viral reproduction HTR2A;SLC20A2;VDAC1 GO:0001503| ossification ALOX15;SLC34A1 GO:0035725| sodium ion transmembrane transport SLC34A2;CACNA1I;CACNA1G;SLC20A2;SLC34A1;SLC34A3;SLC20A1;CACNA1H 18965:[DB14011 DB02417] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02417|2,4,6-Tribromophenol TTR common genes common pathways GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0043312| neutrophil degranulation ALOX5;CAT;TTR GO:0006810| transport TTR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 18966:[DB14011 DB14013] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14013|SR-9009 NR1D1;NR1D2 common genes common pathways GO:0042752| regulation of circadian rhythm NR1D2;NR1D1;PPARG GO:0006351| transcription, DNA-dependent NR1D2;NR1D1;PPARG GO:0045598| regulation of fat cell differentiation PPARG;NR1D1 GO:0043401| steroid hormone mediated signaling pathway NR1D2;NR1D1;PPARG GO:0050727| regulation of inflammatory response PTGS2;NR1D2 GO:0055088| lipid homeostasis PPARG;NR1D2 GO:0019216| regulation of lipid metabolic process NR1D1;CYP1A1;PPARG;HMGCR;CNR1;NR1D2 GO:0045893| positive regulation of transcription, DNA-dependent NR1D2;NR1D1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1D1;NR1D2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1D1;NR1D2 GO:0007623| circadian rhythm AANAT;NR1D1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;NR1D1;TRPV4;TRPV1;NR1D2 GO:0010871| negative regulation of receptor biosynthetic process NR1D1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NR1D1;PPARG;NR1D2 GO:0048511| rhythmic process NR1D1;PPARG;NR1D2;AANAT 18967:[DB14011 DB07410] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways GO:0008299| isoprenoid biosynthetic process HMGCR;GGPS1 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;GGPS1 GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1 18968:[DB14011 DB03542] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways GO:0007165| signal transduction IMPA1;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 18969:[DB14011 DB11979] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes CYP3A7;CYP3A5;CYP3A4;CYP2D6 common pathways GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;ABCB1;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2C8;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;CYP3A43;PTGS1;ALOX5;GPX1;CAT GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP2C8;CYP1A1 GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1;SLCO1B1;CACNA1H;TRPV3;TRPV2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP1A1;CYP2C9 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;GNRHR GO:0006810| transport TRPV2;TRPV1;ABCB1;CACNA1I;ABCG2;ABCC1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C19;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0051100| negative regulation of binding CYP2D6 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA3;SLCO1B1;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2C8;CYP2D6 GO:0097267| CYP1A1;CYP2C9;CYP2C8;CYP2C19;CYP1B1;CYP1A2 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;GNRHR;SMPD1;PPARG;GPR18 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 18970:[DB14011 DB06510] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes PPARG;CYP1A2 common pathways GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0008152| metabolic process UGT1A3;ACAT1;UGT1A1;SMPD1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042953| lipoprotein transport PPARG GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;PPARA;HMGCR;PTGS2;CYP1A2;PTGS1;NAAA;GPX1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARA;PPARG GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;UGT1A1;CYP2D6;CYP2C19 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0006351| transcription, DNA-dependent PPARG;PPARA GO:0001889| liver development ACAT1;CYP1A1;UGT1A1 GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0045471| response to ethanol CAT;OPRM1;HMGCR;SOD1;CNR1;UGT1A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP2C8;CYP3A5;CYP3A4;CYP1A2 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7 GO:0097267| CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP1A2 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;PPARA;CNR1;HMGCR GO:1905461| PPARG GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0055088| lipid homeostasis PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0007584| response to nutrient UGT1A1;PPARG;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;UGT1A1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0006919| activation of caspase activity PPARG GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT;PPARA GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP1A2 GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;PLA2G1B GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation ACAT1;UGT1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;PPARA GO:0045087| innate immune response PPARG GO:0030308| negative regulation of cell growth PPARG GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;IDO1;UGT1A1;CYP1A1 GO:0042060| wound healing PPARA;OPRM1;ALOX15 GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0032526| response to retinoic acid PPARG GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0050728| negative regulation of inflammatory response CNR2;PPARA GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0006631| fatty acid metabolic process ALOX15;PPARA;PTGS2;PTGS1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;UGT1A1;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2C8;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0030224| monocyte differentiation PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A3;CYP2C9;CYP1A1;UGT1A1;CYP2C19;CYP2C8;CYP2D6 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;UGT1A1;CYP3A5;CYP17A1;CYP2C8;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0015909| long-chain fatty acid transport PPARG GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CHRNA7;CAT;PPARA;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0010033| response to organic substance UGT1A1;TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP2C8;CYP3A5 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG 18971:[DB14011 DB00507] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00507|Nitazoxanide SLC19A1 common genes common pathways 18972:[DB14011 DB03294] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03294|1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CA2;TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 18973:[DB14011 DB07776] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes CYP1B1 common pathways GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0006351| transcription, DNA-dependent PPARG;ESRRA;ESRRB GO:0043401| steroid hormone mediated signaling pathway PPARG;ESRRA;ESRRB GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0045821| positive regulation of glycolysis HTR2A;ESRRB GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0042572| retinol metabolic process CYP1B1 GO:0016125| sterol metabolic process CYP17A1;CYP1B1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0002930| CYP1B1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009636| response to toxin GPX1;CAT;CYP1B1;CYP1A1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0008283| cell proliferation GPX1;HTR1A;ESRRB;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0046466| membrane lipid catabolic process CYP1B1 GO:0070301| cellular response to hydrogen peroxide CYP1B1 GO:0030336| negative regulation of cell migration CYP1B1 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESRRB;ESRRA GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESRRA;ESRRB GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0061298| retina vasculature development in camera-type eye CYP1B1 GO:0008210| estrogen metabolic process CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter ESRRA;ESRRB;PPARG GO:0019369| arachidonic acid metabolic process ALOX15;DAGLA;CYP2D6;CYP1B1;FAAH GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0043542| endothelial cell migration CYP1B1 GO:0030199| collagen fibril organization CYP1B1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ESRRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESRRB;ESRRA;TRPV4;TRPV1;PPARG GO:0007155| cell adhesion CYP1B1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESRRB;ESRRA GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0048514| blood vessel morphogenesis CYP1B1 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESRRA GO:0042574| retinal metabolic process CYP1B1 18974:[DB14011 DB06689] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0045471| response to ethanol CAT;HMGCR;OPRM1;SOD1;CNR1;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0010193| response to ozone CYP2E1;CAT GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2E1;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP2E1;ALOX5;GPX1;PTGS1;CAT GO:0042493| response to drug CAT;PTGS2;CYP1A2;CYP2E1;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 GO:0045087| innate immune response F12;PPARG GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2;CYP2E1 18975:[DB14011 DB00922] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0042493| response to drug ABCC1;SMPD1;PDE3A;TRPA1;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;KCNJ11;CAT GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;PDE3A GO:0042311| vasodilation GPX1;KCNJ8 GO:0001822| kidney development KCNJ8;CAT GO:0071333| cellular response to glucose stimulus KCNJ11;SLC29A1 GO:0032496| response to lipopolysaccharide CNR1;KCNJ8;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0071356| cellular response to tumor necrosis factor TRPV1;KCNJ11 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;KCNJ11;CACNA1H;TRPV3;TRPV2 GO:0051591| response to cAMP PDE3A;AANAT GO:0042391| regulation of membrane potential KCNJ11;CACNA1H;GLRA1;CACNA1G;GLRB GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;PDE3A;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;KCNJ11 GO:0009268| response to pH KCNJ8;TRPV1 GO:0007507| heart development KCNJ8;PPARG GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;PTGS1;NAAA;GPX1;PPARG;CYP2C9;PDE3A;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0006811| ion transport CACNA1H;KCNJ8;TRPV3;KCNJ11;GLRA3;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PDE3A;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;KCNJ11;CACNA1H;KCNJ8 GO:0043117| positive regulation of vascular permeability PDE3A;TRPV4 GO:0050796| regulation of insulin secretion CNR1;KCNJ11 18976:[DB14011 DB09328] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes ACAT1;CYP1A2 common pathways GO:1902224| ACAT1 GO:0010468| regulation of gene expression CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0051260| protein homooligomerization GLRA1;ACAT1;GLRA3 GO:0006550| isoleucine catabolic process ACAT1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0006085| acetyl-CoA biosynthetic process ACAT1 GO:0010193| response to ozone CAT;CYP2E1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0006635| fatty acid beta-oxidation ACAT1;ACAA1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;CYP1A1;IDO1 GO:0072229| metanephric proximal convoluted tubule development ACAT1 GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0043312| neutrophil degranulation CAT;ALOX5;ACAA1 GO:0046951| ketone body biosynthetic process ACAT1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;CYP2E1;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;FADS1;CRYZ;CYP2C9;CYP1A1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;CYP2E1;HTR2A;SOD1 GO:0006355| regulation of transcription, DNA-dependent PPARG;FADS1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0006631| fatty acid metabolic process ACAA1;PTGS1;PTGS2;ALOX15;ELOVL4;FADS1 GO:0009083| branched chain family amino acid catabolic process ACAT1 GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 GO:0015936| coenzyme A metabolic process ACAT1;HMGCR GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1;FADS1 GO:0007420| brain development ACAT1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;FADS1;ELOVL4;PLA2G1B GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0009725| response to hormone stimulus ACAT1 GO:0015937| coenzyme A biosynthetic process ACAT1 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0046356| acetyl-CoA catabolic process ACAT1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0046952| ketone body catabolic process ACAT1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0060612| adipose tissue development ACAT1 GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CYP2E1;CAT GO:0001889| liver development CYP1A1;ACAT1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;ACAA1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;ALOX15;ELOVL4;CYP2D6;DAGLA;PLA2G1B;TRPV1;PPARG;CYP2C9;FADS1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0008152| metabolic process ACAA1;ACAT1;SMPD1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:1902860| ACAT1 18977:[DB14011 DB03597] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity PDE5A;HTR2A GO:0042130| negative regulation of T cell proliferation IDO1;PDE5A GO:0008152| metabolic process PDE5A;SMPD1;GSTM4;ACAT1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;SMPD1;PDE5A;GPR18;PPARG;PLA2G1B;CACNA1I;PDE9A GO:0006749| glutathione metabolic process SOD1;GPX1;GSTM4;GSR GO:0042178| xenobiotic catabolic process CRYZ;GSTM4 18978:[DB14011 DB04857] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04857|Brasofensine DRD2 common genes common pathways GO:0001964| startle response GLRA1;GLRB;DRD2 GO:0008542| visual learning DRD2;HMGCR GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0048148| behavioral response to cocaine DRD2;HTR2A GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0001659| temperature homeostasis DRD2;TRPV1;GPX1;HTR2A GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0048678| response to axon injury SOD1;DRD2 GO:0045776| negative regulation of blood pressure DRD2;CNR1 GO:0045471| response to ethanol DRD2;CAT;CNR1;SOD1;OPRM1;HMGCR GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;DRD2;CYP1B1;PPARG GO:0009636| response to toxin GPX1;CAT;CYP1B1;DRD2;CYP1A1 GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0014854| response to inactivity CAT;DRD2 GO:1900273| CHRNA7;DRD2 GO:0050482| arachidonic acid secretion PLA2G1B;DRD2 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;DRD2;PLA2G1B GO:0001975| response to amphetamine DRD2;SOD1;CNR2 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0043278| response to morphine OPRM1;CNR1;DRD2 GO:0042493| response to drug ABCG2;DRD2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;PPARG GO:0007626| locomotory behavior OPRM1;SOD1;DRD2 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0007628| adult walking behavior DRD2;GLRB;GLRA1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;TRPV1;DRD2;GLRB;GLRA1 GO:0001666| response to hypoxia DRD2;CYP1A1;CAT;CHRNA7 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;DRD2;GPR55 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0009416| response to light stimulus AANAT;DRD2 GO:0042220| response to cocaine SMPD1;DRD2;CNR1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;DRD2;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;TRPM8;TRPV4;DRD2 GO:0007186| G-protein coupled receptor signaling pathway DRD2;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;DRD2;TRPV1 18979:[DB14011 DB02661] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways GO:0008152| metabolic process ACAT1;PAPSS1;SMPD1 18980:[DB14011 DB08229] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways GO:0006919| activation of caspase activity CASP3;PPARG GO:0009411| response to UV CASP3;CAT GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;CASP3;PTGS2;CYP1A2 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0007507| heart development PPARG;CASP3 GO:0045165| cell fate commitment PPARG;CASP3 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;CASP3;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;CASP3;SOD1 GO:0006915| apoptotic process VDAC1;GPX1;CASP3 GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0043200| response to amino acid stimulus GLRB;GLRA3;CASP3 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CASP3;TRPA1;CYP1A1;PPARG GO:0001666| response to hypoxia CAT;CHRNA7;CASP3;CYP1A1 GO:0009611| response to wounding CYP1A1;GPX1;CASP3 GO:0032355| response to estradiol stimulus CAT;CASP3;PTGS2;CYP1A2 GO:0007605| sensory perception of sound GPX1;CASP3;SOD1 GO:0071407| cellular response to organic cyclic compound CASP3;CYP1B1;CYP1A1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;CASP3;SOD1;HTR2A;CYP1A2;PTGS2 GO:0035094| response to nicotine CASP3;CHRNA7;CNR1 GO:0007611| learning or memory CASP3;CHRNA7;CNR1 GO:0042060| wound healing OPRM1;CASP3;ALOX15 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CASP3;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;CASP3 GO:0046677| response to antibiotic CASP3;SOD1;CYP1A1 18981:[DB14011 DB02079] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02079|Aminooxyacetic acid AGXT common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;AGXT GO:0051591| response to cAMP AANAT;AGXT 18982:[DB14011 DB05524] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05524|Pelitinib EGFR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;GPX1 GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;EGFR GO:0042060| wound healing ALOX15;EGFR;OPRM1 GO:0007623| circadian rhythm AANAT;EGFR GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0030324| lung development EGFR;CYP1A2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;EGFR GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;PLA2G1B;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;EGFR;TRPV4;ALOX15 GO:0007202| activation of phospholipase C activity HTR2A;GPR55;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;CAT;OPRD1 GO:0032355| response to estradiol stimulus EGFR;CAT;CYP1A2;PTGS2 GO:0033993| response to lipid EGFR;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;EGFR GO:0006979| response to oxidative stress EGFR;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;EGFR GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0006357| regulation of transcription from RNA polymerase II promoter EGFR;PPARG GO:0001889| liver development ACAT1;EGFR;CYP1A1 GO:0051592| response to calcium ion AANAT;EGFR GO:0007166| cell surface receptor linked signaling pathway TRPA1;EGFR;TRPV1 GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification EGFR;ALOX15 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG;EGFR GO:0008283| cell proliferation EGFR;CYP1A1;GPX1;HTR1A GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;EGFR GO:0045740| positive regulation of DNA replication EGFR;PLA2G1B GO:0071276| cellular response to cadmium ion EGFR;SOD1;CYP1A2 GO:0032930| positive regulation of superoxide anion generation SOD1;EGFR GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2;HTR2A GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;EGFR GO:0007165| signal transduction CACNA1I;PLA2G1B;EGFR;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 18983:[DB14011 DB11155] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes CYP1B1;CYP1A1 common pathways GO:0007155| cell adhesion CYP1B1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0030199| collagen fibril organization CYP1B1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0043542| endothelial cell migration CYP1B1 GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0061298| retina vasculature development in camera-type eye CYP1B1 GO:0008210| estrogen metabolic process CYP1B1 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;CYP2D6;DAGLA;FAAH GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0009308| amine metabolic process CYP1A1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0010041| response to iron(III) ion CYP1A1 GO:0042574| retinal metabolic process CYP1B1 GO:0048514| blood vessel morphogenesis CYP1B1 GO:0007568| aging CYP1A1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2 GO:0009611| response to wounding CYP1A1;GPX1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;CYP1A2;PTGS2 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0042572| retinol metabolic process CYP1B1 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0016125| sterol metabolic process CYP17A1;CYP1B1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0070988| demethylation CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0009692| ethylene metabolic process CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;GPX1 GO:0009635| response to herbicide CYP1A1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0043010| camera-type eye development CYP1A1 GO:0032502| developmental process CYP1A1 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1 GO:1900087| CYP1A1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0046466| membrane lipid catabolic process CYP1B1 GO:0017143| insecticide metabolic process CYP1A1 GO:0030336| negative regulation of cell migration CYP1B1 GO:0002930| CYP1B1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009624| response to nematode CYP1A1 GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;CAT GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1 GO:0009636| response to toxin CYP1A1;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 18984:[DB14011 DB00348] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00348|Nitisinone HPD common genes common pathways GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;HPD;CYP1A1;CYP2C9 18985:[DB14011 DB11644] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11644|Tafamidis TTR common genes common pathways GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process CYP1B1;TTR GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;TTR;TRPV2 GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 18986:[DB14011 DB03217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03217|DPI59 SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0042493| response to drug SRC;CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0016236| macroautophagy SRC;VDAC1 GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process SRC;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0009615| response to virus CYP1A1;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response PPARG;SRC GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;SRC;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0002376| immune system process IDO1;SRC GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0043065| positive regulation of apoptotic process SRC;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0042542| response to hydrogen peroxide TRPA1;SOD1;GPX1;SRC;CAT GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0008283| cell proliferation CYP1A1;HTR1A;SRC;GPX1 GO:0045453| bone resorption GPR55;SRC GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;SRC;CHRNA7 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC 18987:[DB14011 DB11751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;TRPV3;CACNA1H;GLRA3;SLC22A8;TRPV2;CHRNA7 GO:0098656| SLC22A8;SLC22A6;VDAC1 GO:0055085| transmembrane transport SLC22A8;CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;SLC22A6;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 18988:[DB14011 DB06923] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06923|2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18989:[DB14011 DB06840] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06840|diethyl [(1R)-1,5-diaminopentyl]boronate PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 18990:[DB14011 DB02076] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways GO:0001525| angiogenesis PTGS2;CYP1B1;GPI GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;GPI GO:0043524| negative regulation of neuron apoptosis GPI;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;GPI GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;GPI GO:0007611| learning or memory CNR1;CHRNA7;GPI GO:0043278| response to morphine OPRM1;CNR1;GPI GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;PGD;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;GPX1;PTGS1 GO:0042593| glucose homeostasis TRPV4;GPI;PPARG;CNR1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;GPI GO:0046686| response to cadmium ion CAT;GPI 18991:[DB14011 DB01203] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes CYP2D6 common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPV1;TRPA1 GO:0050873| brown fat cell differentiation ADRB1;PTGS2;ADRB2 GO:0051100| negative regulation of binding CYP2D6 GO:0001659| temperature homeostasis TRPV1;ADRB1;HTR2A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0009409| response to cold ADRB2;TRPA1;PPARG;ADRB1;TRPM8 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0045453| bone resorption GPR55;ADRB2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;ADRB2;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;ADRB1 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCB1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C9;CYP1A1;CRYZ GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0019369| arachidonic acid metabolic process DAGLA;CYP2D6;ALOX15;CYP1B1;FAAH GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1;ADRB2 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;PLA2G1B GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;ABCB1;TRPV4;CACNA1I;ABCG2;TRPM8 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;ADRB1;HTR2A;CNR1;GPR12;ADRB2;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9 GO:0006810| transport ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1;TRPV2 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 18992:[DB14011 DB08373] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways GO:0009410| response to xenobiotic stimulus GPX1;SCGB1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;CYP1A2;SCGB1A1;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter SCGB1A1;PPARG;TRPV1;TRPV4 GO:0034097| response to cytokine stimulus AANAT;SCGB1A1;PTGS2 GO:0042493| response to drug CAT;CYP1A2;SCGB1A1;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 GO:0010193| response to ozone CAT;SCGB1A1 GO:0010033| response to organic substance SOD1;CYP1A2;SCGB1A1;PTGS2;TRPA1;CYP1A1;PPARG GO:0042130| negative regulation of T cell proliferation IDO1;SCGB1A1 GO:0050727| regulation of inflammatory response PTGS2;SCGB1A1 GO:0007565| female pregnancy SCGB1A1;IDO1 GO:0007566| embryo implantation SOD1;SCGB1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;SCGB1A1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;SCGB1A1;OPRM1;CNR2;CHRNA7 18993:[DB14011 DB01048] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;UGT1A1;PTGS2;CYP1A2;ACAT1;AANAT GO:0007584| response to nutrient UGT1A1;PPARG;HMGCR;CNR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0006955| immune response HLA-B;OPRD1;CNR2 GO:0016032| viral reproduction VDAC1;HLA-B;HTR2A GO:0001889| liver development ACAT1;CYP1A1;UGT1A1 GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1;ADH6;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;UGT1A1;CYP2D6;CYP2C19 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0008152| metabolic process SMPD1;UGT1A1;ACAT1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;UGT1A1;SOD1;PTGS2;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0002376| immune system process HLA-B;IDO1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;ADH6;CYP1A1;CYP2C9;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0042493| response to drug ABCC1;SMPD1;UGT1A1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;IDO1;UGT1A1;CYP1A1 GO:0042594| response to starvation ACAT1;PPARG;UGT1A1 GO:0045087| innate immune response HLA-B;PPARG 18994:[DB14011 DB04512] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04512|2-Isobutyl-3-Methoxypyrazine LCN9 common genes common pathways 18995:[DB14011 DB06475] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06475|Ruplizumab CD40LG common genes common pathways GO:0006955| immune response CD40LG;CNR2;OPRD1 GO:0006954| inflammatory response PTGS1;ALOX5;CD40LG;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;CD40LG;PLA2G1B GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;CD40LG;HMGCR;PTGS2 GO:0032735| positive regulation of interleukin-12 production IDO1;CD40LG 18996:[DB14011 DB04659] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04659|(1S,2S,3R,4S,5S)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways GO:0008152| metabolic process SMPD1;LCT;ACAT1 18997:[DB14011 DB04912] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04912|Stannsoporfin HMOX1;HMOX2 common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;HMOX2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;HMOX1 GO:0035094| response to nicotine CNR1;HMOX1;CHRNA7 GO:0055114| oxidation-reduction process CRYZ;HMOX2;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;HMOX1;ALOX5;GPX1;PTGS1;CAT GO:0006979| response to oxidative stress HMOX2;CAT;GPX1;PTGS1;HMOX1;SOD1;PTGS2 GO:0051260| protein homooligomerization ACAT1;GLRA3;HMOX1;GLRA1 GO:0034605| cellular response to heat TRPV1;TRPV4;HMOX1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;HMOX1;SLC29A1 GO:0001666| response to hypoxia CYP1A1;HMOX2;HMOX1;CHRNA7;CAT GO:0008219| cell death HTR2A;HMOX1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;HMOX1 GO:0006915| apoptotic process VDAC1;GPX1;HMOX1 GO:0035556| intracellular signal transduction HMOX1;PLA2G1B GO:0042542| response to hydrogen peroxide CAT;GPX1;HMOX1;SOD1;TRPA1 GO:0043065| positive regulation of apoptotic process PTGS2;HMOX1;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0001525| angiogenesis PTGS2;HMOX1;CYP1B1 GO:1904706| PPARG;HMOX1 GO:0006879| cellular iron ion homeostasis HMOX1;SOD1;HMOX2;ABCG2 GO:0043524| negative regulation of neuron apoptosis HMOX1;SOD1 GO:0048662| negative regulation of smooth muscle cell proliferation HMOX1;PPARG GO:0071276| cellular response to cadmium ion HMOX1;SOD1;CYP1A2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;HMOX1;SOD1;PPARG GO:0008285| negative regulation of cell proliferation HMOX1;OPRM1;PTGS2;CYP1B1;PPARG GO:1902042| HMOX1;GPX1 GO:0043627| response to estrogen stimulus HMOX1;PPARG 18998:[DB14011 DB07189] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07189|(1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid ADAM17 common genes common pathways GO:0001934| positive regulation of protein phosphorylation ADAM17;CHRNA7 GO:0042493| response to drug PPARG;CYP1A1;ADAM17;TRPA1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0050830| defense response to Gram-positive bacterium PLA2G1B;ADAM17 GO:0007155| cell adhesion CYP1B1;ADAM17 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;ADAM17 GO:0032496| response to lipopolysaccharide CYP1A1;ADAM17;IDO1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;ADAM17 GO:0002446| neutrophil mediated immunity ADAM17;PLA2G1B 18999:[DB14011 DB11090] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways GO:0034765| regulation of ion transmembrane transport KCNH2;CACNA1H;CACNA1I;CACNA1G GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;GLRA3;KCNH2;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0086091| KCNH2;CACNA1G GO:0086010| CACNA1G;CACNA1I;CACNA1H;KCNH2 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;GLRB;GLRA1;CACNA1G GO:0055085| transmembrane transport TRPV2;TRPV3;KCNH2;CACNA1H;TRPM8;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;ABCC1;CACNA1G GO:0033629| negative regulation of cell adhesion mediated by integrin MUC1;CYP1B1 19000:[DB14011 DB03642] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03642|Benzofuran-2-Carboxylic Acid {(S)-3-Methyl-1-[3-Oxo-1-(Pyridin-2-Ylsulfonyl)Azepan-4-Ylcarbamoyl]Butyl}Amide CTSK common genes common pathways GO:0045453| bone resorption GPR55;CTSK GO:1903146| VDAC1;CTSK 19001:[DB14011 DB02685] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02685|3-Methylphenylalanine CTSB common genes common pathways GO:0046697| decidualization CTSB;PTGS2 GO:0030855| epithelial cell differentiation VDAC1;CTSB;PPARG GO:0043312| neutrophil degranulation CAT;ALOX5;CTSB GO:0046718| entry of virus into host cell HTR2A;CTSB 19002:[DB14011 DB04878] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04878|Voglibose MGAM common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;MGAM GO:0043312| neutrophil degranulation CAT;MGAM;ALOX5 19003:[DB14011 DB00113] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;CEACAM1 GO:0007155| cell adhesion CEACAM1;CYP1B1 GO:0032869| cellular response to insulin stimulus CEACAM1;PPARG;PLA2G1B GO:0001525| angiogenesis CEACAM1;PTGS2;CYP1B1 19004:[DB14011 DB11132] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11132|Silicon dioxide MARCO common genes common pathways GO:0045087| innate immune response PPARG;MARCO GO:0002376| immune system process MARCO;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;MARCO;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0043277| apoptotic cell clearance MARCO;ALOX15 GO:0007166| cell surface receptor linked signaling pathway MARCO;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation MARCO;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;MARCO 19005:[DB14011 DB00311] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CA3;CAT GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0098656| SLC22A6;VDAC1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;SOD1;PTGS2;CYP1A2 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4 GO:0051260| protein homooligomerization SLC22A6;GLRA1;ACAT1;GLRA3 GO:0006979| response to oxidative stress PTGS2;SOD1;CA3;PTGS1;GPX1;CAT GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 19006:[DB14011 DB00308] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GLRA1;CACNA1G;CACNB1;GLRB;VDAC1 GO:0098703| TRPV1;CACNA2D1 GO:0006816| calcium ion transport CACNA2D1;CACNA1H;TRPV3;CACNG1;CHRNA7;TRPV2;CACNA1C;TRPA1;CACNA1G;CACNB1;TRPM8;TRPV1;TRPV4;CACNA1I GO:0086010| CACNA1G;CACNA1I;KCNH2;CACNA1H GO:0051924| regulation of calcium ion transport OPRD1;CACNA2D1 GO:0086091| CACNA1C;KCNH2;CACNA2D1;KCNH6;CACNA1G GO:0035725| sodium ion transmembrane transport CACNA1G;KCNK1;CACNA1I;CACNA1H GO:0007507| heart development CACNA1C;PPARG GO:0006811| ion transport CACNB1;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;KCNH6;TRPA1;GLRA1;KCNK1;CACNA1G;KCNH7;CACNG1;CHRNA7;TRPV2;KCNK6;CACNA1C;KCNJ11;CACNA2D1;GLRA3;KCNH2;CACNA1H;TRPV3 GO:0086045| CACNA1C;CACNA1G GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;CACNA1C;TRPV1;TRPV4 GO:0050796| regulation of insulin secretion CNR1;KCNJ11;CACNA1C GO:0043010| camera-type eye development CACNA1C;CYP1A1 GO:0034765| regulation of ion transmembrane transport KCNJ11;CACNA2D1;KCNH2;CACNA1H;CACNG1;KCNK6;CACNA1C;CACNA1G;KCNH7;CACNB1;KCNH6;CACNA1I GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1H;TRPV3;CACNA2D1;TRPV2;CACNA1C;CACNG1;CHRNA7;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;CACNB1;TRPM8 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;KCNJ11;PTGS2;CYP1A2;CAT GO:0035094| response to nicotine CHRNA7;CNR1;KCNK1 GO:0071333| cellular response to glucose stimulus KCNJ11;SLC29A1 GO:0086002| CACNA1G;CACNA2D1;CACNA1C GO:0055085| transmembrane transport KCNJ11;TRPV3;KCNH2;CACNA1H;CACNA1C;TRPV2;TRPA1;ABCC1;CACNA1G;KCNH7;TRPM8;ABCG2;KCNH6;VDAC1;CACNA1I;TRPV4;TRPV1 GO:0071356| cellular response to tumor necrosis factor KCNJ11;TRPV1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;KCNJ11;CAT GO:0006810| transport ABCG2;CACNB1;TRPV1;CACNA1I;ABCC1;CACNG1;TRPV2 GO:0006936| muscle contraction CACNA1H;CACNG1;GLRA1 GO:0042391| regulation of membrane potential CACNA1H;KCNH2;KCNJ11;GLRB;KCNH6;KCNH7;CACNA1G;GLRA1 19007:[DB14011 DB02048] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02048|1,2,4-Triazole-Carboxamidine NOS3 common genes common pathways GO:0009408| response to heat TRPV1;NOS3;TRPV2;TRPV3;SOD1 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0001525| angiogenesis CYP1B1;NOS3;PTGS2 GO:1902042| NOS3;GPX1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1;NOS3 GO:0008217| regulation of blood pressure NOS3;PPARG;PTGS1;PTGS2;SOD1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0045454| cell redox homeostasis GPX1;GSR;NOS3 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;GSR;IDO1;CYP2D6;NOS3;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0042311| vasodilation NOS3;GPX1 GO:0030324| lung development CYP1A2;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;NOS3 19008:[DB14011 DB09237] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes CYP3A4 common pathways GO:0006809| nitric oxide biosynthetic process NOS2;NOS3;CYP1B1 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0086045| CACNA1G;CACNA1C GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;CACNA1C;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation PPARG;NOS3;CYP1B1;PTGS2;OPRM1 GO:1902042| NOS3;GPX1 GO:0050796| regulation of insulin secretion CNR1;CACNA1C;NOS2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;CACNA1C;TRPV1;TRPV4 GO:0045454| cell redox homeostasis NOS2;NOS3;GSR;GPX1 GO:0043010| camera-type eye development CACNA1C;CYP1A1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0070588| calcium ion transmembrane transport TRPM8;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1C;OPRM1;CACNA1H;TRPV3 GO:0034765| regulation of ion transmembrane transport CACNA1H;CACNA1C;CACNA1G;CACNA1I GO:0008209| androgen metabolic process CYP3A4 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1C;CACNA1H;TRPV3 GO:0009408| response to heat NOS3;TRPV1;TRPV2;SOD1;TRPV3 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure NOS3;NOS2;CNR1 GO:0086091| CACNA1C;CACNA1G GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;NAAA;GPX1;PTGS1;PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B GO:0007507| heart development PPARG;CACNA1C GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0045766| positive regulation of angiogenesis CYP1B1;NOS3;CHRNA7 GO:0086002| CACNA1C;CACNA1G GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPV3;CACNA1H;CACNA1C;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;NOS2;CAT;CHRNA7 GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALOX5;PTGS1;GPX1;CRYZ;NOS2;CYP2C9;CYP1A1;IDO1;GSR;CYP2C19;NOS3;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0030324| lung development NOS3;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;NOS2;CYP1A1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0042311| vasodilation NOS3;GPX1 19009:[DB14011 DB06869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06869|1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;F2;PPARG;GPR18 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;F2 19010:[DB14011 DB04368] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04368|Bb-3497 def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;PDF 19011:[DB14011 DB03273] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03273|3'-Oxo-Adenosine AHCY common genes common pathways GO:0032259| methylation AHCY;CYP1A2 GO:0001666| response to hypoxia CAT;CHRNA7;AHCY;CYP1A1 GO:0007584| response to nutrient AHCY;PPARG;CNR1;HMGCR 19012:[DB14011 DB04214] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 19013:[DB14011 DB03078] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03078|PASBN SRC common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0009615| response to virus CYP1A1;SRC GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;SRC;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;SRC;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0002376| immune system process IDO1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;SRC;GPX1 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;SRC;PTGS2;CNR1;SOD1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0031667| response to nutrient levels SRC;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC GO:0045453| bone resorption GPR55;SRC GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;SRC;CHRNA7 GO:0070542| response to fatty acid PTGS2;CAT;SRC GO:0008283| cell proliferation CYP1A1;HTR1A;SRC;GPX1 19014:[DB14011 DB05382] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05382|Iodine MT-ND5 common genes common pathways GO:0042542| response to hydrogen peroxide TRPA1;MT-ND5;SOD1;CAT;GPX1 GO:0010243| response to organic nitrogen PTGS2;MT-ND5;TRPV1 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;MT-ND5;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6 GO:0001666| response to hypoxia CYP1A1;MT-ND5;CHRNA7;CAT 19015:[DB14011 DB02490] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 19016:[DB14011 DB02106] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways GO:0043401| steroid hormone mediated signaling pathway THRB;PPARG GO:0006351| transcription, DNA-dependent PPARG;THRB GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;PPARG GO:0008016| regulation of heart contraction THRB;CACNA1H GO:0006355| regulation of transcription, DNA-dependent PPARG;THRB GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;THRB;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;PLA2G1B;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;THRB GO:0007605| sensory perception of sound THRB;SOD1;GPX1 19017:[DB14011 DB08011] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08011|(3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;MAPK10 GO:0000187| activation of MAPK activity CHRNA7;SOD1;MAPK10;PLA2G1B GO:0048511| rhythmic process MAPK10;PPARG;AANAT GO:0009416| response to light stimulus AANAT;MAPK10 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;MAPK10 GO:0042752| regulation of circadian rhythm MAPK10;PPARG 19018:[DB14011 DB02723] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02723|4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-Amide F2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;F2 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0061844| PLA2G1B;F2 19019:[DB14011 DB07702] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07702|17alpha-Estriol NCOA5;ESR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR2;TRPV4;TRPV1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2 GO:0006355| regulation of transcription, DNA-dependent NCOA5;ESR2;PPARG GO:0042593| glucose homeostasis TRPV4;NCOA5;PPARG;CNR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR2 GO:0006351| transcription, DNA-dependent NCOA5;ESR2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG GO:0007165| signal transduction GPR18;PPARG;SMPD1;ESR2;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 19020:[DB14011 DB03539] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03539|2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose CHIT1 common genes common pathways GO:0006955| immune response CNR2;OPRD1;CHIT1 GO:0008152| metabolic process CHIT1;SMPD1;ACAT1 GO:0043312| neutrophil degranulation ALOX5;CAT;CHIT1 19021:[DB14011 DB02730] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02730|4-Methylthio-Alpha-D-Mannose AMY2B common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;AMY2B 19022:[DB14011 DB04348] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes ABCC1;ABCG2 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;SLC16A1;CEL;FABP6;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;ABCB11 GO:0043401| steroid hormone mediated signaling pathway NR1H4;PPARG GO:0006351| transcription, DNA-dependent NR1H4;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NR1H4 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0009408| response to heat TRPV1;ABCC2;TRPV3;SOD1;TRPV2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS1;ALOX5;CNR2;PTGS2;NR1H4 GO:0016032| viral reproduction HTR2A;VDAC1;SLC10A1 GO:0046415| urate metabolic process ABCG2 GO:0007565| female pregnancy ABCC2;IDO1 GO:0007420| brain development ACAT1;SLC7A11 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;NR1H4;OPRD1 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0050796| regulation of insulin secretion SLC16A1;CNR1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC3;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0046718| entry of virus into host cell HTR2A;SLC10A1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;FABP6;PTGS2;OPRM1 GO:0098656| SLC22A6;VDAC1;SLC22A8 GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCB1;ABCC1;ABCC3 GO:0006811| ion transport SLCO1B1;SLC22A8;GLRA3;SLCO1B3;SLCO1A2;TRPV3;SLCO3A1;CACNA1H;CHRNA7;SLCO4A1;TRPV2;GLRA1;TRPA1;SLCO1C1;CACNA1G;SLCO2B1;TRPM8;SLC10A2;SLC10A1;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;NR1H4;CAT GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;ABCC4;AANAT;ACAT1 GO:0009636| response to toxin CAT;GPX1;SLC22A8;SLC7A11;CYP1B1;CYP1A1 GO:0045087| innate immune response PPARG;NR1H4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;NR1H4 GO:0002576| platelet degranulation ABCC4;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process NR1H4;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0033344| cholesterol efflux ABCG2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;ABCC2;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0009062| fatty acid catabolic process FAAH;CEL GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1H4 GO:0015886| heme transport ABCG2 GO:0035094| response to nicotine SLC7A11;CNR1;CHRNA7 GO:0060326| cell chemotaxis ABCC1 GO:0010243| response to organic nitrogen ABCC4;PTGS2;TRPV1 GO:0050728| negative regulation of inflammatory response NR1H4;CNR2 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2;HMGCR GO:0055114| oxidation-reduction process ABCC4;GPX1;ALOX5;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0042493| response to drug CAT;ABCC4;HTR2A;SOD1;PTGS2;CYP1A2;ABCC2;ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0006355| regulation of transcription, DNA-dependent NR1H4;PPARG GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1A1;CYP1B1 GO:0032094| response to food SLC16A1;OPRM1;CYP1A1 GO:0099133| ABCC2;ABCC11;ABCC3;ABCC1;ABCC4;ABCC10 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;NR1H4;CHRNA7 GO:0051260| protein homooligomerization SLC22A6;GLRA1;ACAT1;GLRA3 GO:0002376| immune system process NR1H4;IDO1 GO:0042593| glucose homeostasis SLC16A1;CNR1;NR1H4;TRPV4;PPARG GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;SLC7A11;PTGS2;ABCC2 GO:0006810| transport ABCC3;ABCC1;TRPV1;CACNA1I;ABCB1;SLC10A2;SLC10A1;ABCG2;ABCC2;ABCB11;TRPV2 GO:0009235| cobalamin metabolic process ABCC1 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;ABCC4;PPARG;CYP1A1;TRPA1 GO:0055085| transmembrane transport TRPM8;SLCO2B1;ABCC2;SLC51B;ABCG2;ABCC11;SLC10A2;SLC10A1;TRPV1;CACNA1I;ABCB1;TRPV4;VDAC1;SLC51A;TRPA1;ABCC3;SLCO1C1;ABCC1;SLC22A6;CACNA1G;SLCO4A1;SLC16A1;ABCC4;TRPV2;SLCO1B1;ABCC10;SLC22A8;ABCB11;SLCO1B3;TRPV3;SLCO1A2;SLCO3A1;CACNA1H GO:0007043| cell-cell junction assembly TRPV4;NR1H4 GO:0016042| lipid catabolic process NAPEPLD;PLA2G1B;DAGLA;CEL 19023:[DB14011 DB04771] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04771|1-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;F2 19024:[DB14011 DB08035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006351| transcription, DNA-dependent AR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0007165| signal transduction CHRNA7;AR;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 GO:0008285| negative regulation of cell proliferation AR;OPRM1;PTGS2;CYP1B1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;TRPV1;TRPV4;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;AR;TRPV2 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis SOD1;CNR1;AR 19025:[DB14011 DB03338] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PPARD GO:0042060| wound healing ALOX15;PPARD;OPRM1 GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;PPARD;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;PPARD;HMGCR;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;TRPV4;TRPV1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARD GO:0050728| negative regulation of inflammatory response PPARD;CNR2 GO:0033189| response to vitamin A PPARG;CYP1A1;PPARD;CAT GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;TRPV1;FKBP1A GO:0046697| decidualization PTGS2;PPARD GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PPARD;PTGS2 GO:0006936| muscle contraction GLRA1;FKBP1A;CACNA1H GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0006915| apoptotic process GPX1;PPARD;VDAC1 GO:0010628| positive regulation of gene expression TRPV4;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0031000| response to caffeine PPARG;FKBP1A GO:0015758| glucose transport PPARD;PLA2G1B GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;PPARD;SOD1 GO:1902991| CHRNA7;FKBP1A GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0006351| transcription, DNA-dependent PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARD GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;PPARD;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0007507| heart development PPARD;PPARG GO:0007566| embryo implantation PTGS2;PPARD;SOD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;TRPV3;OPRM1;CACNA1H;TRPM8;FKBP1A;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G GO:0008283| cell proliferation GPX1;PPARD;HTR1A;CYP1A1 GO:0001890| placenta development PPARG;SOD1;PPARD GO:0060612| adipose tissue development PPARD;ACAT1 GO:0019395| fatty acid oxidation PPARD;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARD;PPARG GO:0014823| response to activity PPARD;CAT 19026:[DB14011 DB07354] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways GO:0016032| viral reproduction VDAC1;TOP1;HTR2A GO:0048511| rhythmic process TOP1;AANAT;PPARG GO:0007623| circadian rhythm TOP1;AANAT GO:0042493| response to drug HTR2A;SOD1;TOP1;CYP1A2;PTGS2;CAT;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 19027:[DB14011 DB04895] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04895|Pegaptanib NRP1 common genes common pathways GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;NRP1 GO:0043524| negative regulation of neuron apoptosis NRP1;SOD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;NRP1 GO:0001525| angiogenesis CYP1B1;PTGS2;NRP1 GO:0007399| nervous system development NRP1;GLRB;SMPD1 GO:0007507| heart development PPARG;NRP1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;NRP1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0007413| axonal fasciculation NRP1;CNR1 GO:0043542| endothelial cell migration CYP1B1;NRP1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;NRP1;OPRM1;HMGCR;ALOX15;TRPV4 GO:0031532| actin cytoskeleton reorganization NRP1;TRPV4 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;NRP1 GO:0140059| NRP1;CHRNA7 GO:0009611| response to wounding CYP1A1;GPX1;NRP1 19028:[DB14011 DB14581] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14581|CPI-1205 EZH2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;EZH2 GO:0032259| methylation EZH2;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter EZH2;PPARG;TRPV4;TRPV1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;EZH2 GO:0043406| positive regulation of MAP kinase activity EZH2;HTR2A GO:0048511| rhythmic process PPARG;EZH2;AANAT GO:0045892| negative regulation of transcription, DNA-dependent EZH2;PPARG GO:0032355| response to estradiol stimulus EZH2;PTGS2;CYP1A2;CAT GO:0010468| regulation of gene expression EZH2;CYP1A2 GO:0042752| regulation of circadian rhythm EZH2;PPARG GO:0010629| negative regulation of gene expression EZH2;OPRD1 GO:0006357| regulation of transcription from RNA polymerase II promoter EZH2;PPARG GO:0006351| transcription, DNA-dependent EZH2;PPARG GO:0070301| cellular response to hydrogen peroxide EZH2;CYP1B1 19029:[DB14011 DB14499] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14499|Potassium sulfate ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure PPARG;ATP1A1;SOD1;PTGS2;PTGS1 GO:0006811| ion transport TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;ATP1A1;GLRA3;TRPV3;CACNA1H GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0034220| ion transmembrane transport ATP1A1;GLRA3;CHRNA7;GLRA1;TRPA1;TRPV1;GLRB GO:0086002| CACNA1G;ATP1A1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;ATP1A1;HTR2A;SOD1 19030:[DB14011 DB06695] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;UGT1A9 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0009636| response to toxin CYP1A1;CYP1B1;CES1;CAT;GPX1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0008152| metabolic process UGT2B7;ACAT1;CES1;UGT1A9;SMPD1;UGT2B15 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CES2;CYP1B1;CYP2C9;UGT2B15;NQO2;UGT1A9 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1;CES2 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;UGT2B7;GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;GPR18;PPARG;F2 GO:0008202| steroid metabolic process UGT2B15;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;HMGCR;CYP3A7;CYP1A2;CYP3A4;UGT2B7 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCB1;ABCG2;ABCC1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0017144| drug metabolic process UGT1A9;CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;TRPV4;ABCB1;CACNA1I;VDAC1 GO:0030855| epithelial cell differentiation VDAC1;PPARG;CES1 GO:0006695| cholesterol biosynthetic process CES1;HMGCR GO:0008284| positive regulation of cell proliferation F2;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0042493| response to drug ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;NQO2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;NQO2;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1 19031:[DB14011 DB04661] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways GO:0016032| viral reproduction HTR2A;CD1D;VDAC1 GO:0045087| innate immune response CD1D;PPARG GO:0002376| immune system process IDO1;CD1D 19032:[DB14011 DB02343] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0007517| muscle organ development CACNA1H;ACHE GO:0007155| cell adhesion ACHE;CYP1B1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;ACHE GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development GLRB;SMPD1;ACHE 19033:[DB14011 DB06990] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06990|4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID UNG common genes common pathways GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;UNG GO:0016032| viral reproduction VDAC1;UNG;HTR2A 19034:[DB14011 DB08819] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08819|Tafluprost PTGFR;PTGS2 common genes PTGS2 common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;PTGFR;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;PTGFR GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0010628| positive regulation of gene expression TRPV4;PTGFR GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0008284| positive regulation of cell proliferation PTGFR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;PTGFR GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;OPRM1;CYP1A2;PTGS2;CNR2;PTGFR GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;PTGS1;GPX1 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PTGFR;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;NAAA;PTGS1;GPX1 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ALOX5;PTGS1;CNR2;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 19035:[DB14011 DB00627] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes CYP2D6 common pathways GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0010243| response to organic nitrogen PTGS2;NNMT;TRPV1 GO:0019369| arachidonic acid metabolic process FAAH;ALOX15;DAGLA;CYP2D6;CYP1B1 GO:0032094| response to food CYP1A1;SLC16A1;OPRM1 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1B1;CYP1A1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;NNMT;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;GPX1;PTGS1;CRYZ;CYP2C9;CYP1A1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0032259| methylation NNMT;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0006915| apoptotic process SLC5A8;VDAC1;GPX1;HCAR2 GO:0055085| transmembrane transport SLC22A5;TRPV3;CACNA1H;SLC16A1;TRPV2;SLC16A3;TRPA1;ABCC1;CACNA1G;SLCO2B1;TRPM8;ABCG2;TRPV1;SLC5A8;VDAC1;CACNA1I;TRPV4 GO:0042593| glucose homeostasis TRPV4;PPARG;SLC16A1;CNR1 GO:0031100| organ regeneration PPARG;NNMT GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HCAR3;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;HCAR2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;PPARG;CYP2C9;SLC16A1;GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0051100| negative regulation of binding CYP2D6 GO:0006811| ion transport TRPV3;CACNA1H;SLC22A5;GLRA3;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;SLC5A8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;SLCO2B1;TRPM8 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A5 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;HCAR2;GPR18;PPARG;SMPD1;HCAR3;CACNA1I;PLA2G1B GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway NNMT;SLC5A8;PTGS2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 19036:[DB14011 DB00050] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;LHCGR;GPR55;HTR1A;HTR2A;CNR1;GPR12;GNRHR;PPARG;GPR18 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR2;CNR1;LHCGR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;LHCGR;OPRD1;OPRM1 GO:0050890| cognition CHRNA7;LHCGR GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;GNRHR;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;LHCGR;HTR1A;GPR55;CHRNA7 19037:[DB14011 DB06732] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes CYP1A2;CYP1B1 common pathways GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042572| retinol metabolic process CYP1B1 GO:0007399| nervous system development SMPD1;GLRB;NR2F1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process AHR;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0016125| sterol metabolic process CYP17A1;CYP1B1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESRRA;NR2F1;ESR1 GO:0006351| transcription, DNA-dependent NR2F1;ESR1;ESRRA;AHR;PPARG GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0009403| toxin biosynthetic process CYP1A2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AHR;PPARG GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;NR2F1;OPRM1;OPRD1;ESR1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;ESR1;OPRM1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0046466| membrane lipid catabolic process CYP1B1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0070301| cellular response to hydrogen peroxide CYP1B1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0030336| negative regulation of cell migration CYP1B1 GO:0009791| post-embryonic development CYP1A2 GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0002930| CYP1B1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1 GO:0009636| response to toxin AHR;CYP1A1;CYP1B1;GPX1;CAT GO:0045333| cellular respiration CYP1A2 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0007155| cell adhesion CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NR2F1;PPARG;ESRRA;TRPV4;TRPV1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR2F1;PPARG;AHR;ESRRA;PLA2G1B GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0043542| endothelial cell migration CYP1B1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0030199| collagen fibril organization CYP1B1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0009410| response to xenobiotic stimulus GPX1;AHR GO:0042127| regulation of cell proliferation PTGS2;PTGS1;ESRRA GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESRRA;NR2F1;ESR1 GO:0008210| estrogen metabolic process CYP1B1 GO:0061298| retina vasculature development in camera-type eye CYP1B1 GO:0019369| arachidonic acid metabolic process FAAH;ALOX15;CYP2D6;DAGLA;CYP1B1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;PTGS1;ALOX5;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESRRA;PPARG;AHR GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent ESR1;NR2F1;PPARG;AHR;ESRRA GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0042574| retinal metabolic process CYP1B1 GO:0048514| blood vessel morphogenesis CYP1B1 GO:0010468| regulation of gene expression CYP1A2;AHR GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT;ESRRA GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent AHR;PPARG GO:0048511| rhythmic process AHR;PPARG;AANAT GO:0010977| negative regulation of neuron projection development NR2F1;TRPV4 GO:0006915| apoptotic process GPX1;AHR;VDAC1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 19038:[DB14011 DB05983] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0000060| protein import into nucleus, translocation OPRD1;NFKBIA GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;NFKBIA GO:0016032| viral reproduction VDAC1;NFKBIA;HTR2A GO:0071345| cellular response to cytokine stimulus NFKBIA;TRPV1 GO:0050729| positive regulation of inflammatory response NFKBIA;TRPV4 GO:0032088| negative regulation of NF-kappaB transcription factor activity NFKBIA;CYP1B1;CAT GO:0010745| negative regulation of macrophage derived foam cell differentiation NFKBIA;PPARG GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;CYP1A1;IDO1;NFKBIA GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NFKBIA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NFKBIA;PLA2G1B GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;NFKBIA GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NFKBIA GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;NFKBIA GO:0010468| regulation of gene expression NFKBIA;CYP1A2 GO:0006915| apoptotic process GPX1;NFKBIA;VDAC1 GO:0071356| cellular response to tumor necrosis factor NFKBIA;TRPV1 19039:[DB14011 DB09336] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways GO:0001657| ureteric bud development EPCAM;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter EPCAM;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation EPCAM;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A 19040:[DB14011 DB09532] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09532|Secretin human SCTR common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;SCTR GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;SCTR;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;SCTR 19041:[DB14011 DB04100] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0007565| female pregnancy ABCC2;IDO1 GO:0009408| response to heat TRPV2;SOD1;TRPV3;ABCC2;TRPV1 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCG2 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;CYP1A1;IDO1;ABCC2 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;ABCC2 GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0006810| transport TRPV2;ABCG2;ABCC2;TRPV1;CACNA1I;ABCC1 GO:0006979| response to oxidative stress ABCC2;GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0055085| transmembrane transport TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;ABCC2;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 19042:[DB14011 DB03041] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways GO:0043085| positive regulation of catalytic activity B3GAT3;SOD1 19043:[DB14011 DB03556] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03556|2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 CBR1;CBR1 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CBR1;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0030855| epithelial cell differentiation CBR1;VDAC1;PPARG GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;CBR1;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0019371| cyclooxygenase pathway PTGS1;CBR1;PTGS2 19044:[DB14011 DB04151] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04151|4-Methyl-Histidine ACTA1 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;ACTA1 GO:0048741| skeletal muscle fiber development GPX1;ACTA1 GO:0006936| muscle contraction GLRA1;CACNA1H;ACTA1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;ACTA1 GO:0010226| response to lithium ion ACTA1;PTGS2 19045:[DB14011 DB07549] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07549|2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;F2 19046:[DB14011 DB00126] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0009404| toxin metabolic process CYP1A2;CYP1A1;PAM;CYP1B1 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;SLC23A1;VDAC1;TRPV4;CACNA1I;TRPV1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0006915| apoptotic process GPX1;EGLN3;VDAC1 GO:0046688| response to copper ion PAM;SOD1;AANAT GO:0001666| response to hypoxia CHRNA7;CAT;PLOD2;PLOD1;EGLN1;EGLN3;EGLN2;CYP1A1;PAM GO:0032355| response to estradiol stimulus PAM;PTGS2;CYP1A2;CAT GO:0042593| glucose homeostasis TRPV4;PPARG;DBH;CNR1 GO:0051260| protein homooligomerization GLRA1;PAM;GLRA3;ACAT1 GO:1901214| CHRNA7;EGLN1 GO:0006355| regulation of transcription, DNA-dependent PPARG;KDM5D GO:0042493| response to drug PPARG;CYP1A1;TRPA1;PAM;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0006631| fatty acid metabolic process PTGS2;PTGS1;PHYH;ALOX15 GO:0055114| oxidation-reduction process P3H3;SOD1;ALKBH3;PLOD2;CYP3A4;TMLHE;KDM5D;HMGCR;PTGS2;CYP3A7;P3H2;CYP1A2;PLOD1;PLOD3;DBH;CAT;ALKBH2;GPX1;ALOX5;PTGS1;CRYZ;OGFOD2;PHYH;P4HTM;CYP2C9;CYP1A1;PAM;CYP2D6;BBOX1;EGLN1;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;EGLN3;OGFOD1;P3H1;P4HA1;CYP1B1;EGLN2 GO:0048265| response to pain TRPV1;TRPA1;DBH GO:0042127| regulation of cell proliferation EGLN3;DBH;PTGS1;PTGS2 GO:0060135| maternal process involved in female pregnancy CNR1;PAM GO:0043523| regulation of neuron apoptosis EGLN3;EGLN2;GPX1 GO:0030324| lung development CYP1A2;SLC23A1 GO:0030199| collagen fibril organization PLOD3;P4HA1;CYP1B1 GO:0007626| locomotory behavior DBH;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;EGLN1 GO:0042311| vasodilation PLOD3;GPX1 GO:0008283| cell proliferation HTR1A;ALKBH3;GPX1;CYP1A1;OGFOD1 GO:0006811| ion transport TRPM8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPA1;GLRA1;SLC23A1;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H GO:0006139| nucleobase-containing compound metabolic process SLC23A1;SLC29A1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;SLC23A1;CYP1A1 GO:0006919| activation of caspase activity PPARG;EGLN3 GO:0008285| negative regulation of cell proliferation P3H3;PTGS2;OPRM1;P3H2;PPARG;P3H1;CYP1B1 GO:0051384| response to glucocorticoid stimulus PTGS2;PAM GO:0001975| response to amphetamine DBH;SOD1;CNR2 GO:0045454| cell redox homeostasis GPX1;EGLN2;GSR GO:0007613| memory DBH;CHRNA7;HTR2A;CNR1;PTGS2 GO:0070989| oxidative demethylation ALKBH2;CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0045907| positive regulation of vasoconstriction DBH;PTGS2;HTR2A GO:0032870| cellular response to hormone stimulus CACNA1H;PLOD3 GO:0007420| brain development ACAT1;SLC23A1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;DBH;CACNA1G;GLRA1;GLRB;VDAC1 GO:0048149| behavioral response to ethanol DBH;OPRM1 GO:0007595| lactation SLC29A1;PAM GO:0009268| response to pH PAM;TRPV1 GO:0006879| cellular iron ion homeostasis EGLN1;ABCG2;SOD1 GO:0008542| visual learning HMGCR;DBH GO:0006357| regulation of transcription from RNA polymerase II promoter PAM;PPARG GO:0006351| transcription, DNA-dependent KDM5D;PPARG GO:0035725| sodium ion transmembrane transport CACNA1I;SLC23A1;CACNA1G;CACNA1H GO:0008152| metabolic process ACAT1;SMPD1;PAM;LCT GO:0007507| heart development PPARG;PAM 19047:[DB14011 DB03442] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways GO:0031100| organ regeneration PPARG;ATIC GO:0008152| metabolic process SMPD1;ATIC;ACAT1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;ATIC 19048:[DB14011 DB09413] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09413|Monopotassium phosphate ALPI common genes common pathways GO:0006654| phosphatidic acid biosynthetic process ALPI;PLA2G1B GO:0008152| metabolic process ALPI;SMPD1;ACAT1 19049:[DB14011 DB06360] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06360|Lucatumumab CD40 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;CD40 GO:0006955| immune response OPRD1;CNR2;CD40 GO:0051092| positive regulation of NF-kappaB transcription factor activity CD40;PLA2G1B;CAT GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;CD40;ALOX5;PTGS1;CNR2;PTGS2 GO:0031667| response to nutrient levels CD40;SOD1 GO:0001934| positive regulation of protein phosphorylation CD40;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CD40;PLA2G1B GO:0042127| regulation of cell proliferation PTGS2;PTGS1;CD40 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;CYP1A1;CD40;IDO1 GO:0006874| cellular calcium ion homeostasis CD40;TRPM8;TRPV4;HTR2A;GPR12;CHRNA7 GO:0002376| immune system process CD40;IDO1 GO:0032735| positive regulation of interleukin-12 production CD40;IDO1 GO:0043406| positive regulation of MAP kinase activity CD40;HTR2A GO:0071356| cellular response to tumor necrosis factor TRPV1;CD40 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;CD40 19050:[DB14011 DB07122] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07122|1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine PLAU common genes common pathways GO:0001666| response to hypoxia CYP1A1;PLAU;CHRNA7;CAT GO:0043312| neutrophil degranulation PLAU;CAT;ALOX5 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLAU;PLA2G1B;CACNA1I 19051:[DB14011 DB03581] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03581|Glucose-6-Phosphate glmS;GPI;SLCO2A1 common genes common pathways GO:0007611| learning or memory CHRNA7;CNR1;GPI GO:0043312| neutrophil degranulation GPI;ALOX5;CAT GO:0035902| response to immobilization stress CYP1A2;GPI;CYP1A1;PPARG GO:0043278| response to morphine GPI;CNR1;OPRM1 GO:0032355| response to estradiol stimulus GPI;CAT;CYP1A2;PTGS2 GO:0042593| glucose homeostasis CNR1;TRPV4;GPI;PPARG GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;SLCO2A1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0046686| response to cadmium ion GPI;CAT GO:0001525| angiogenesis PTGS2;GPI;CYP1B1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;GPX1;PTGS2 GO:0043524| negative regulation of neuron apoptosis GPI;SOD1 19052:[DB14011 DB00035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes PTGS1;PTGS2 common pathways GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0051970| negative regulation of transmission of nerve impulse AVPR1A;GLRA1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation AVPR1A;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;AVPR2 GO:0034097| response to cytokine stimulus AVPR2;PTGS2;AANAT GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0014902| myotube differentiation AVPR1A;GPX1 GO:0071284| cellular response to lead ion PTGS2 GO:0007202| activation of phospholipase C activity AVPR1B;AVPR1A;GPR55;HTR2A GO:0010628| positive regulation of gene expression AVPR2;TRPV4 GO:0010033| response to organic substance AVPR1A;SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:1902219| PTGS2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;AVPR1A;AVPR1B;GPR18;PPARG;AVPR2 GO:0007568| aging CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CYP1A1 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger AVPR2;CNR1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process AVPR1A;PTGS2 GO:0042633| hair cycle PTGS2 GO:0045777| positive regulation of blood pressure AVPR2;CNR1;AVPR1A GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0032870| cellular response to hormone stimulus CACNA1H;AVPR1A;AVPR2;AVPR1B GO:0045907| positive regulation of vasoconstriction AVPR2;AVPR1B;AVPR1A;HTR2A;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0051412| response to corticosterone stimulus AVPR1A;AANAT GO:0070542| response to fatty acid PTGS2;CAT GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0007165| signal transduction SMPD1;AVPR1B;GPR18;PPARG;AVPR2;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;AVPR1A;HTR1A;GPR55;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration AVPR1B;TRPV4;TRPV1;AVPR1A;HTR2A;OPRM1 19053:[DB14011 DB02745] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02745|Uridine LSM6;SLC29A1 common genes SLC29A1 common pathways GO:1901642| SLC29A1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;TRPV1;GLRB GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1 GO:0015858| nucleoside transport SLC29A1 GO:0007595| lactation SLC29A1 GO:0030431| sleep HTR2A;SLC29A1;CACNA1I GO:0015862| uridine transport SLC29A1 19054:[DB14011 DB04059] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04059|8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0043312| neutrophil degranulation ALOX5;CAT;PLAU GO:0001666| response to hypoxia PLAU;CYP1A1;CHRNA7;CAT GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLAU;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 19055:[DB14011 DB11660] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11660|Latanoprostene Bunod PTGFR;SLCO2B1 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;PTGFR GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;PTGFR;CHRNA7 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1;PTGFR GO:0010628| positive regulation of gene expression PTGFR;TRPV4 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;SLCO2B1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0032355| response to estradiol stimulus PTGFR;CAT;CYP1A2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;PTGFR;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8;SLCO2B1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PTGFR;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B 19056:[DB14011 DB09217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09217|Firocoxib PTGS2 common genes PTGS2 common pathways GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CYP1A1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning PTGS2;VDAC1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR1;HTR2A;PTGS2;CNR2;OPRM1;OPRD1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 19057:[DB14011 DB00430] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0001895| retina homeostasis ALB;SOD1 19058:[DB14011 DB05017] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05017|YSIL6 TNF;IL6 common genes common pathways GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;IL6;PPARG;TNF;SMPD1 GO:0031622| positive regulation of fever generation PTGS2;CNR1;TNF GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL6 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF;IL6 GO:0006955| immune response IL6;TNF;CNR2;OPRD1 GO:0006954| inflammatory response TNF;TRPV1;IL6;ALOX15;IDO1;PTGS2;CNR2;PTGS1;ALOX5 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;PLA2G1B;IL6;CAT GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;TNF;IL6 GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0050796| regulation of insulin secretion CNR1;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF;IL6 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1;IL6 GO:0070301| cellular response to hydrogen peroxide IL6;CYP1B1 GO:0006919| activation of caspase activity PPARG;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TNF;TRPV4;TRPV1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;IL6 GO:0009615| response to virus TNF;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;PPARG;IL6;PLA2G1B GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;IL6 GO:0046330| positive regulation of JNK cascade TRPV4;TNF GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0042127| regulation of cell proliferation PTGS2;PTGS1;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;IL6;TNF GO:0046427| positive regulation of JAK-STAT cascade IL6;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent IL6;PPARG;TNF GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0050830| defense response to Gram-positive bacterium IL6;PLA2G1B;TNF GO:0032966| negative regulation of collagen biosynthetic process IL6;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TNF;TRPV1 GO:0002446| neutrophil mediated immunity IL6;PLA2G1B GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TNF;TRPA1;CYP1A2;PTGS2;SOD1 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0010628| positive regulation of gene expression IL6;TRPV4;TNF GO:0000187| activation of MAPK activity TNF;PLA2G1B;SOD1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15;TNF 19059:[DB14011 DB03506] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03506|9-Deazaadenine APRT common genes common pathways GO:0007595| lactation APRT;SLC29A1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;APRT GO:0043312| neutrophil degranulation APRT;CAT;ALOX5 19060:[DB14011 DB03455] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways GO:0065009| regulation of molecular function TRPV1;IL2 GO:0050729| positive regulation of inflammatory response TRPV4;IL2 GO:0007204| elevation of cytosolic calcium ion concentration IL2;TRPV1;TRPV4;HTR2A;OPRM1 GO:0006955| immune response IL2;OPRD1;CNR2 GO:0030217| T cell differentiation IL2;GPR18 GO:0001934| positive regulation of protein phosphorylation CHRNA7;IL2 GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;IL2 GO:0002376| immune system process IL2;IDO1 GO:0007186| G-protein coupled receptor signaling pathway IL2;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0050728| negative regulation of inflammatory response IL2;CNR2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IL2;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;IL2 GO:0007155| cell adhesion IL2;CYP1B1 19061:[DB14011 DB12119] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12119|Gevokizumab IL1B common genes common pathways GO:0001934| positive regulation of protein phosphorylation IL1B;CHRNA7 GO:0006954| inflammatory response ALOX15;IL1B;IDO1;TRPV1;PTGS1;ALOX5;PTGS2;CNR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IL1B;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL1B GO:0006955| immune response IL1B;CNR2;OPRD1 GO:2000778| positive regulation of interleukin-6 secretion IL1B;TRPV4 GO:0010575| positive regulation vascular endothelial growth factor production IL1B;CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation IL1B;CNR1;PTGS2 GO:0071260| cellular response to mechanical stimulus IL1B;PTGS2 GO:0051781| positive regulation of cell division CAT;IL1B GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;IL1B;PPARG GO:0007566| embryo implantation SOD1;PTGS2;IL1B GO:0050796| regulation of insulin secretion IL1B;CNR1 GO:0034116| positive regulation of heterotypic cell-cell adhesion IL1B;ALOX15 GO:0007165| signal transduction GPR18;PPARG;SMPD1;IL1B;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0045893| positive regulation of transcription, DNA-dependent IL1B;PPARG GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;IL1B GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;CYP1A1;IDO1;IL1B GO:0001660| fever generation TRPV1;IL1B GO:0046330| positive regulation of JNK cascade TRPV4;IL1B GO:0071639| positive regulation of monocyte chemotactic protein-1 production IL1B;TRPV4 GO:0008284| positive regulation of cell proliferation IL1B;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IL1B;PPARG GO:0045766| positive regulation of angiogenesis CHRNA7;IL1B;CYP1B1 GO:0006915| apoptotic process GPX1;IL1B;VDAC1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;IL1B;PLA2G1B GO:0010628| positive regulation of gene expression IL1B;TRPV4 GO:0043407| negative regulation of MAP kinase activity SMPD1;IL1B;HMGCR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;IL1B;OPRM1;PTGS2 19062:[DB14011 DB07617] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;HMGCR;CYP3A7;CYP1A2;CYP2A6;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP2A6;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2;CYP2A6 GO:0055114| oxidation-reduction process SOD1;CYP2A6;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0009804| coumarin metabolic process CYP2A6;CYP1A1;CYP2D6 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP2A6;CYP3A4;CYP1A2 19063:[DB14011 DB13751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13751|Glycyrrhizic acid HSD11B1;TNF;CASP3;NFKB2;NFKB1;LPL;AKR1C4;AKR1C3;AKR1C2;ALB;ABCB11 common genes common pathways GO:0009411| response to UV CASP3;CAT GO:0006919| activation of caspase activity CASP3;PPARG;TNF GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CASP3;AANAT;ACAT1;CYP1A2;PTGS2 GO:0001895| retina homeostasis ALB;SOD1 GO:0001523| retinoid metabolic process LPL;AKR1C4;NAPEPLD;AKR1C3 GO:0071276| cellular response to cadmium ion CYP1A2;AKR1C3;SOD1 GO:0007584| response to nutrient PPARG;AKR1C3;HMGCR;CNR1 GO:0050729| positive regulation of inflammatory response LPL;TRPV4 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3;TNF GO:0050796| regulation of insulin secretion TNF;CNR1 GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0006641| triglyceride metabolic process LPL;CAT;GPX1 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;TNF GO:0006633| fatty acid biosynthetic process LPL;PLA2G1B;PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2;OPRD1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;NFKB1;CHRNA7;SMPD1;PPARG;NFKB2;GPR18;CACNA1I;PLA2G1B GO:0071379| cellular response to prostaglandin stimulus AKR1C3;PPARG GO:0010629| negative regulation of gene expression TNF;NFKB1;OPRD1 GO:0019371| cyclooxygenase pathway PTGS2;AKR1C3;PTGS1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF GO:0008209| androgen metabolic process AKR1C4;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0006955| immune response TNF;CNR2;OPRD1 GO:0042448| progesterone metabolic process CYP17A1;AKR1C2;AKR1C3 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;TNF;NFKB2;NFKB1;CAT GO:0006954| inflammatory response TNF;NFKB2;TRPV1;IDO1;ALOX15;PTGS2;CNR2;ALOX5;PTGS1;NFKB1 GO:0010942| positive regulation of cell death PTGS2;AKR1C3 GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;PPARG GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;CACNA1H;ABCB11 GO:0006351| transcription, DNA-dependent NFKB2;PPARG;NFKB1 GO:0000060| protein import into nucleus, translocation TNF;AKR1C3;OPRD1 GO:0071277| cellular response to calcium ion AKR1C3;ALOX15 GO:0031622| positive regulation of fever generation CNR1;PTGS2;TNF GO:0006693| prostaglandin metabolic process PTGS2;AKR1C3;PTGS1;AKR1C2 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0009409| response to cold TRPM8;LPL;TRPA1;PPARG GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;TNF;PPARG;SMPD1;CASP3;CNR1;SOD1;PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;GPX1;CASP3 GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;DAGLA;AKR1C2;CYP2D6;PLA2G1B;TRPV1;LPL;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;HSD11B1;GPX1;NAAA;PTGS1 GO:0042572| retinol metabolic process CYP1B1;AKR1C3 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0007507| heart development CASP3;PPARG GO:0045165| cell fate commitment CASP3;PPARG GO:0016042| lipid catabolic process NAPEPLD;LPL;PLA2G1B;DAGLA GO:0043200| response to amino acid stimulus GLRB;CASP3;GLRA3 GO:0006915| apoptotic process VDAC1;GPX1;CASP3;NFKB1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;TNF GO:0030855| epithelial cell differentiation VDAC1;AKR1C2;PPARG GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0055085| transmembrane transport TRPV2;ABCB11;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;ABCC1;CACNA1G GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;CASP3 GO:0010628| positive regulation of gene expression TRPV4;TNF GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CASP3;TNF;TRPA1;PPARG;CYP1A1 GO:0006644| phospholipid metabolic process PLA2G1B;LPL;NAPEPLD GO:0045892| negative regulation of transcription, DNA-dependent NFKB1;PPARG;TNF GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0071356| cellular response to tumor necrosis factor TRPV1;NFKB1 GO:0048511| rhythmic process NFKB2;PPARG;AANAT GO:0008202| steroid metabolic process HSD11B1;CYP3A7;CYP1A2;AKR1C3;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2D6;AKR1C2;CYP2C19;CYP2C9;CYP1A1;AKR1C4 GO:0032355| response to estradiol stimulus CASP3;CAT;CYP1A2;PTGS2 GO:0009611| response to wounding GPX1;CASP3;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;AKR1C2;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;AKR1C3 GO:0007568| aging CYP1A1;NFKB2;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT GO:0006810| transport ABCC1;CACNA1I;TRPV1;ABCG2;ABCB11;TRPV2 GO:0098869| GSR;ALB;CAT;GPX1;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TNF;PTGS2;OPRM1 GO:0042574| retinal metabolic process CYP1B1;AKR1C3 GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B1 GO:0007605| sensory perception of sound SOD1;CASP3;GPX1 GO:0071407| cellular response to organic cyclic compound CASP3;CYP1B1;CYP1A1;TNF GO:0022900| electron transport chain CYP1A2;AKR1C4;IDO1;GSR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF;NFKB1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;CASP3;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;LPL GO:0006355| regulation of transcription, DNA-dependent NFKB2;PPARG;NFKB1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;AKR1C4;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;AKR1C2;CYP3A5;ALOX15;CYP17A1;HMGCR;AKR1C3;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;HSD11B1;CAT GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2;HMGCR GO:0050728| negative regulation of inflammatory response NFKB1;CNR2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;AKR1C3;AKR1C2;TNF GO:0035094| response to nicotine CHRNA7;CASP3;CNR1 GO:0007611| learning or memory CHRNA7;CASP3;CNR1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;TNF GO:0042060| wound healing ALOX15;CASP3;OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;CASP3;CYP1A1;NFKB2;IDO1 GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0030324| lung development HSD11B1;CYP1A2 GO:0071230| cellular response to amino acid stimulus TNF;GLRA1 GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;CASP3;GPX1;NFKB1;CAT GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0046677| response to antibiotic SOD1;CASP3;CYP1A1 GO:0002576| platelet degranulation ALB;SOD1 GO:0009615| response to virus CYP1A1;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;NFKB2;PLA2G1B;NFKB1 GO:0008284| positive regulation of cell proliferation AKR1C2;CHRNA7;PTGS2;AKR1C3;HMGCR;HTR1A;HTR2A GO:0043312| neutrophil degranulation NFKB1;CAT;ALOX5 GO:0034097| response to cytokine stimulus NFKB2;PTGS2;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;TRPV4;TRPV1;PPARG;NFKB2;TNF GO:0045087| innate immune response NFKB1;PPARG;NFKB2 19064:[DB14011 DB03711] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03711|6-Hydroxy-6-Methyl-Heptan-3-One LCN9 common genes common pathways 19065:[DB14011 DB04793] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04793|1,4:3,6-Dianhydro-2-O-(3-carbamimidoylphenyl)-5-O-(4-carbamimidoylphenyl)-D-glucitol PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19066:[DB14011 DB00081] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;FCGR1A;SMPD1;GPR18;FCGR2B;PPARG;CHRNA7;FCGR2C;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;IDO1;ALOX15;FCGR2B GO:0016032| viral reproduction HTR2A;FCGR2B;VDAC1 GO:0006955| immune response C1R;FCGR3B;FCGR2B;FCGR1A;FCGR2C;OPRD1;FCGR3A;CNR2;C1QC GO:0002376| immune system process C1QB;C1R;FCGR2A;FCGR1A;IDO1;C1QC;C1QA GO:0046330| positive regulation of JNK cascade TRPV4;FCGR2B GO:0045087| innate immune response C1QC;C1QA;PPARG;C1R;C1QB;FCGR1A GO:0043312| neutrophil degranulation CAT;ALOX5;FCGR3B;FCGR2A 19067:[DB14011 DB02587] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes common pathways GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADCY2 GO:0035556| intracellular signal transduction PLA2G1B;ADCY2;ADCY5 GO:0071320| cellular response to cAMP AANAT;CFTR GO:1902476| GLRA3;CFTR;GLRA1;GLRB GO:0050890| cognition CHRNA7;GNAS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration ADCY5;HTR2A;OPRM1;TRPV4;TRPV1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY2;ADCY5;OPRM1;OPRD1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006821| chloride transport GLRA1;CFTR;GLRB;GLRA3 GO:0007165| signal transduction PLA2G1B;ADCY2;CACNA1I;GNAS;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0006811| ion transport TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;CFTR;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0009791| post-embryonic development CYP1A2;GNAS GO:0006695| cholesterol biosynthetic process CFTR;HMGCR GO:0007626| locomotory behavior ADCY5;OPRM1;SOD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;ADCY5;GNAS GO:0042493| response to drug ABCB1;GNAS;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0099133| CFTR;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway ADCY5;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GNAS;ADCY2;GPR18;PPARG GO:0006810| transport ABCC1;CACNA1I;ABCB1;TRPV1;ABCG2;TRPV2 GO:0055085| transmembrane transport CFTR;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;ABCB1;CACNA1I;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0050891| multicellular organismal water homeostasis CFTR;TRPV4 19068:[DB14011 DB08049] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0043627| response to estrogen stimulus COMT;PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG;COMT GO:0051930| regulation of sensory perception of pain COMT;OPRM1;OPRD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;COMT GO:0032502| developmental process COMT;CYP1A1 GO:0007565| female pregnancy IDO1;COMT GO:0048265| response to pain TRPA1;COMT;TRPV1 GO:0008210| estrogen metabolic process COMT;CYP1B1 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;CYP1A1;PPARG;TRPA1;COMT;ABCC1;SMPD1;ABCG2 GO:0032259| methylation CYP1A2;COMT GO:0007612| learning VDAC1;COMT;PTGS2 GO:0032496| response to lipopolysaccharide COMT;CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0007614| short-term memory CHRNA7;COMT 19069:[DB14011 DB03040] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03040|Nitrilotriacetic Acid LTF common genes common pathways GO:0001895| retina homeostasis LTF;SOD1 GO:0002227| innate immune response in mucosa LTF;PLA2G1B GO:0006811| ion transport TRPM8;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G;LTF;CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H GO:0061844| PLA2G1B;LTF GO:0006351| transcription, DNA-dependent PPARG;LTF GO:0001503| ossification ALOX15;LTF GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;LTF;PLA2G1B GO:0002376| immune system process LTF;IDO1 GO:0043312| neutrophil degranulation LTF;CAT;ALOX5 GO:0045087| innate immune response LTF;PPARG GO:0043066| negative regulation of apoptotic process LTF;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0019731| antibacterial humoral response PLA2G1B;LTF GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LTF GO:0006355| regulation of transcription, DNA-dependent LTF;PPARG 19070:[DB14011 DB01330] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01330|Cefotetan ALB common genes common pathways GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0098869| ALB;GSR;PTGS1;GPX1;CAT;PTGS2 GO:0001895| retina homeostasis SOD1;ALB 19071:[DB14011 DB06549] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06549|Labradimil BDKRB2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;BDKRB2 GO:0042310| vasoconstriction BDKRB2;HTR1A GO:0006954| inflammatory response BDKRB2;CNR2;PTGS2;ALOX5;PTGS1;IDO1;ALOX15;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration BDKRB2;OPRM1;HTR2A;TRPV1;TRPV4 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;BDKRB2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0050482| arachidonic acid secretion PLA2G1B;BDKRB2 GO:0006939| smooth muscle contraction HTR2A;BDKRB2 GO:0042311| vasodilation GPX1;BDKRB2 GO:1902219| BDKRB2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;GPR55;HTR1A;BDKRB2;OPRD1;CNR2;OPRM1;GPR18;PPARG 19072:[DB14011 DB01043] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes CHRNA7;CYP2C19 common pathways GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN1 GO:0009416| response to light stimulus DRD2;AANAT GO:1902991| CHRNA7 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;DRD2 GO:0140059| CHRNA7 GO:0001666| response to hypoxia DRD2;CYP1A1;CAT;CHRNA7 GO:1905920| CHRNA7 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;SLC22A2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;DRD2;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7 GO:0042220| response to cocaine OPRM1;CNR1;DRD2;HTR3A;SMPD1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0095500| CHRNA7 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;GRIN3A;HTR3A;GLRB;TRPV1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2B6;CYP2C19;CYP2D6;CYP3A4;CYP2A6;CYP1A2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:1901214| CHRNA7 GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;GRIN1;TRPM8;DRD2;TRPV4 GO:0042391| regulation of membrane potential GRIN2A;GRIN1;CACNA1H;GLRB;GLRA1;CACNA1G GO:0006810| transport GRIN2B;TRPV2;GRIN2A;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0009611| response to wounding GPX1;GRIN2A;CYP1A1 GO:0051209| release of sequestered calcium ion into cytosol DRD2;TRPV1;TRPA1;HTR2A GO:0071363| cellular response to growth factor stimulus TRPV1;HTR3A;CAT;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;DRD2;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0098815| CHRNA7 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP2B6;CYP1A1;CYP2C9 GO:0050893| sensory processing CHRNA7 GO:0043278| response to morphine CNR1;OPRM1;GRIN1;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0009804| coumarin metabolic process CYP2A6;CYP2D6;CYP1A1 GO:0050808| synapse organization CHRNA7 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP2A6;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;CYP2B6;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1 GO:0050905| neuromuscular process GRIN1;GLRA1;GLRB GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;DRD2;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;GRIN2A;CAT GO:0007628| adult walking behavior GLRA1;DRD2;GLRB GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;DRD2;GRIN1 GO:0007626| locomotory behavior SOD1;OPRM1;DRD2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP2A6;CYP1A2 GO:1905144| CHRNA7 GO:0007614| short-term memory CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2B;GLRA3;OPRM1;GRIN1;CHRNA7;GRIN2A;SLC29A1;GRIN3A;GLRA1;TRPV1;GLRB;DRD2 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:1905906| CHRNA7 GO:0007612| learning PTGS2;GRIN1;GRIN2A;VDAC1 GO:0010524| positive regulation of calcium ion transport into cytosol GRIN1;PLA2G1B GO:0043523| regulation of neuron apoptosis GPX1;GRIN1 GO:0007611| learning or memory GRIN2A;CHRNA7;GRIN1;GRIN2B;CNR1 GO:0006812| cation transport TRPM8;SLC22A2;GRIN1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;DRD2;OPRM1;PTGS2 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0014854| response to inactivity DRD2;CAT GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A2 GO:0008344| adult locomotory behavior GRIN1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;GRIN2A GO:0006811| ion transport HTR3A;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;SLC22A2;CACNA1G;TRPA1;GLRA1;GRIN3A;TRPV2;CHRNA7;GRIN2A;TRPV3;CACNA1H;GRIN1;GLRA3;GRIN2B GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0009636| response to toxin DRD2;CYP1B1;CYP1A1;GPX1;CAT GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0007165| signal transduction CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;HTR3A;PLA2G1B;CACNA1I;DRD2 GO:0065009| regulation of molecular function TRPV1;GRIN2A;GRIN1;GRIN2B GO:0070588| calcium ion transmembrane transport GRIN3A;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:1900273| GRIN2A;CHRNA7;DRD2 GO:0050482| arachidonic acid secretion PLA2G1B;DRD2 GO:1904645| CHRNA7 GO:0007613| memory CHRNA7;GRIN2A;GRIN1;PTGS2;CNR1;HTR2A GO:0043576| regulation of respiratory gaseous exchange GLRA1;GRIN1 GO:0022008| neurogenesis DAGLA;GRIN2A GO:0050890| cognition CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0001975| response to amphetamine CNR2;GRIN1;SOD1;GRIN2A;DRD2 GO:0008542| visual learning DRD2;HMGCR;GRIN1;GRIN2A GO:1902430| CHRNA7 GO:0006816| calcium ion transport TRPA1;GRIN3A;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1;TRPV3;GRIN1;CACNA1H;GRIN2A;CHRNA7;TRPV2 GO:0001964| startle response GLRA1;DRD2;GLRB;GRIN1;GRIN2A GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902004| CHRNA7 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP2C19 GO:0007268| synaptic transmission OPRM1;OPRD1;GRIN2B;GLRA3;HTR2A;GRIN2A;CACNA1G;GLRA1;GLRB;VDAC1;HTR3A GO:0043524| negative regulation of neuron apoptosis SOD1;GRIN1 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0060078| regulation of postsynaptic membrane potential GRIN2A;CHRNA7 GO:0001659| temperature homeostasis DRD2;TRPV1;HTR2A;GPX1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;GRIN2A;SOD1;CNR1;PTGS2;GRIN1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP2B6 GO:0042428| serotonin metabolic process GRIN2A;HTR1A GO:0048148| behavioral response to cocaine DRD2;HTR2A GO:0045776| negative regulation of blood pressure DRD2;CNR1 GO:0045471| response to ethanol GRIN2A;CAT;CNR1;SOD1;GRIN2B;HMGCR;GRIN1;OPRM1;HTR3A;DRD2;GRIN3A GO:0030431| sleep GRIN2A;SLC29A1;HTR2A;CACNA1I GO:0019233| sensory perception of pain TRPV1;TRPA1;GRIN2A;HTR2A;CNR1;OPRD1;GRIN1;CNR2;PTGS2;OPRM1 GO:0048678| response to axon injury DRD2;SOD1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 19073:[DB14011 DB09472] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09472|Sodium sulfate CA2;CA1 common genes common pathways GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1;CA2 GO:0001822| kidney development CA2;CAT GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 19074:[DB14011 DB00968] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0071312| cellular response to alkaloid TRPV1;DDC GO:0046219| indolalkylamine biosynthetic process DDC;AANAT GO:0007565| female pregnancy COMT;IDO1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;DDC GO:0050796| regulation of insulin secretion CNR1;ADRA2A GO:0032502| developmental process COMT;CYP1A1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRM1;OPRD1 GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0048662| negative regulation of smooth muscle cell proliferation COMT;PPARG GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;ADRA2A GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;SLC15A1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7 GO:0051930| regulation of sensory perception of pain COMT;OPRD1;OPRM1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;COMT;ACAT1;AANAT;PTGS2;CYP1A2 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;DDC;CAT GO:0043627| response to estrogen stimulus COMT;PPARG GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0007612| learning PTGS2;COMT;VDAC1 GO:0007623| circadian rhythm AANAT;DDC GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;COMT;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0007614| short-term memory COMT;CHRNA7 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0032259| methylation CYP1A2;COMT GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;COMT GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0008210| estrogen metabolic process COMT;CYP1B1 GO:0048265| response to pain TRPA1;COMT;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;DDC;OPRD1 GO:0006810| transport TRPV2;ABCC1;SLC15A1;CACNA1I;TRPV1;ABCG2 GO:0042593| glucose homeostasis ADRA2A;TRPV4;PPARG;CNR1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1;SLC15A1;TRPA1;ABCC1;CACNA1G GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A 19075:[DB14011 DB02405] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways GO:2000778| positive regulation of interleukin-6 secretion TRPV4;PAEP GO:0006915| apoptotic process VDAC1;PAEP;GPX1 19076:[DB14011 DB01711] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01711|2,3,4,5,6-Pentafluorobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ADH1C;ALOX5;GPX1;PTGS1;CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 19077:[DB14011 DB07901] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07901|5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE METAP1 common genes common pathways 19078:[DB14011 DB01620] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01620|Pheniramine HRH1;NR1I3 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I3 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;HRH1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I3 GO:0006355| regulation of transcription, DNA-dependent NR1I3;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;PLA2G1B;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;HTR2A GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;NR1I3;HRH1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1;HTR2A GO:0007613| memory CHRNA7;CNR1;HTR2A;HRH1;PTGS2 GO:0008542| visual learning HRH1;HMGCR GO:0006954| inflammatory response HRH1;CNR2;PTGS2;PTGS1;ALOX5;IDO1;ALOX15;TRPV1 GO:0006351| transcription, DNA-dependent NR1I3;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1I3;PPARG 19079:[DB14011 DB08952] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08952|Indenolol CYP2D6 common genes CYP2D6 common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;PTGS1;NAAA;GPX1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0051100| negative regulation of binding CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 19080:[DB14011 DB03637] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03637|Guanidine-3-Propanol PRSS3 common genes common pathways GO:0009235| cobalamin metabolic process PRSS3;ABCC1 GO:0043312| neutrophil degranulation PRSS3;ALOX5;CAT GO:0043542| endothelial cell migration PRSS3;CYP1B1 19081:[DB14011 DB02010] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02010|Staurosporine LCK;PIM1;ITK;SYK;MAPKAPK2;GSK3B;CSK;CDK2;PIK3CG;PDPK1;PRKCQ;ZAP70;CHRM1;ABCB1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SYK GO:0016032| viral reproduction LCK;VDAC1;SYK;HTR2A GO:0006955| immune response ZAP70;CNR2;OPRD1 GO:0030217| T cell differentiation GPR18;ZAP70;LCK GO:0006954| inflammatory response SYK;PIK3CG;MAPKAPK2;PRKCQ;TRPV1;IDO1;ALOX15;PTGS2;CNR2;ALOX5;PTGS1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCQ;PLA2G1B;CAT GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B;SYK GO:0071320| cellular response to cAMP AANAT;PIK3CG GO:0043524| negative regulation of neuron apoptosis SOD1;PDPK1 GO:0007399| nervous system development SMPD1;GLRB;CHRM1;GSK3B GO:0035556| intracellular signal transduction GSK3B;ITK;PLA2G1B;PRKCQ;ZAP70;SYK;PDPK1 GO:0006351| transcription, DNA-dependent PDPK1;PPARG GO:0001525| angiogenesis PTGS2;SYK;PIK3CG;CYP1B1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;SYK;TRPA1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CSK;CYP1B1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0070233| negative regulation of T cell apoptosis PRKCQ;IDO1 GO:0006919| activation of caspase activity LCK;PPARG GO:0008283| cell proliferation SYK;CYP1A1;GPX1;PIM1;HTR1A;CHRM1 GO:0007420| brain development ACAT1;CSK GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;CHRM1;GPR55;HTR1A;CNR1;GPR12;HTR2A;ITK;CHRNA7 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;PIK3CG GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0032869| cellular response to insulin stimulus PDPK1;PPARG;PLA2G1B GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;PIK3CG;OPRM1;HTR2A GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0050890| cognition CHRM1;CHRNA7 GO:0060326| cell chemotaxis PRKCQ;ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PIK3CG;LCK GO:0071404| cellular response to low-density lipoprotein particle stimulus SYK;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG GO:0006355| regulation of transcription, DNA-dependent PRKCQ;PPARG;PDPK1 GO:0030593| neutrophil chemotaxis SYK;PIK3CG;PLA2G1B GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;LCK;ABCB1;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;MAPKAPK2;ALOX5 GO:0045087| innate immune response LCK;CSK;SYK;PIK3CG;PPARG;ZAP70;ITK GO:0000122| negative regulation of transcription from RNA polymerase II promoter CDK2;PPARG;TRPV1;TRPV4 GO:0034097| response to cytokine stimulus PTGS2;AANAT;MAPKAPK2 GO:0043066| negative regulation of apoptotic process GSK3B;CAT;GPX1;SOD1;HMGCR;PIM1;PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRM1;CHRNA7;CDK2 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;GLRA1;CHRNA7;GSK3B;SLC29A1;GLRA3;OPRM1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;MAPKAPK2;CYP1A1 GO:0042127| regulation of cell proliferation ZAP70;CSK;LCK;PTGS2;ITK;PTGS1 GO:0007623| circadian rhythm GSK3B;AANAT GO:0010033| response to organic substance CDK2;TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 GO:0048511| rhythmic process PPARG;GSK3B;AANAT GO:0043406| positive regulation of MAP kinase activity CSK;PIK3CG;HTR2A GO:0010628| positive regulation of gene expression TRPV4;GSK3B GO:0007202| activation of phospholipase C activity HTR2A;GPR55;ITK GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;PDPK1 GO:0000187| activation of MAPK activity SYK;PLA2G1B;MAPKAPK2;SOD1;CHRNA7 GO:0006915| apoptotic process VDAC1;GPX1;PIM1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G GO:0043085| positive regulation of catalytic activity PIK3CG;SOD1 GO:0002376| immune system process ITK;SYK;PIK3CG;ZAP70;PRKCQ;IDO1;CSK GO:0048514| blood vessel morphogenesis SYK;CYP1B1 GO:0006810| transport ABCG2;ABCB1;CACNA1I;TRPV1;ABCC1;TRPV2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;PIK3CG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CHRM1;CNR1;GPR12;HTR2A GO:0051209| release of sequestered calcium ion into cytosol TRPV1;LCK;TRPA1;HTR2A 19082:[DB14011 DB09035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09035|Nivolumab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PDCD1;PTGS2;CAT;GPX1 GO:0070234| positive regulation of T cell apoptosis PDCD1;IDO1 GO:0002376| immune system process IDO1;PDCD1 GO:0006915| apoptotic process VDAC1;PDCD1;GPX1 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;PDCD1;CNR1;SOD1 GO:0007165| signal transduction CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;PDCD1;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B 19083:[DB14011 DB03028] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03028|1h-Benoximidazole-2-Carboxylic Acid CTSD common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;CTSD 19084:[DB14011 DB12159] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12159|Dupilumab IL4R common genes common pathways GO:0002376| immune system process IDO1;IL4R GO:0042127| regulation of cell proliferation PTGS1;PTGS2;IL4R GO:0007165| signal transduction GPR55;HTR1A;IL4R;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0043627| response to estrogen stimulus IL4R;PPARG GO:0030728| ovulation PTGS2;IL4R GO:0006955| immune response OPRD1;CNR2;IL4R 19085:[DB14011 DB08770] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;ADORA2A;CYP1B1 GO:0042755| eating behavior ADORA2A;OPRD1;OPRM1 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1;SOD1 GO:0007165| signal transduction GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;ADORA2A;SMPD1;PLA2G1B;CACNA1I GO:0001975| response to amphetamine CNR2;SOD1;ADORA2A GO:0006954| inflammatory response PTGS2;CNR2;PTGS1;ALOX5;ADORA2A;TRPV1;IDO1;ALOX15 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0007600| sensory perception ADORA2A;TRPV2;OPRM1 GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADORA2A;CNR1 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0031000| response to caffeine PPARG;ADORA2A GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0006915| apoptotic process GPX1;ADORA2A;VDAC1 GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0007186| G-protein coupled receptor signaling pathway GPR18;ADORA2A;PPARG;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0050728| negative regulation of inflammatory response ADORA2A;CNR2 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;TRPA1;ADORA2A;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ADORA2A GO:0007626| locomotory behavior ADORA2A;SOD1;OPRM1 GO:0042311| vasodilation ADORA2A;GPX1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;ADORA2A;GLRA1;TRPV1;GLRB 19086:[DB14011 DB02900] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways GO:0001889| liver development IGF2R;CYP1A1;ACAT1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;IGF2R;PPARG;PTGS2;SOD1;CNR1 GO:0007165| signal transduction PLA2G1B;CACNA1I;IGF2R;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;M6PR;OPRM1;CNR2 GO:0009791| post-embryonic development CYP1A2;IGF2R GO:0032526| response to retinoic acid PPARG;IGF2R GO:0043312| neutrophil degranulation CAT;ALOX5;IGF2R GO:0007186| G-protein coupled receptor signaling pathway GPR18;IGF2R;PPARG;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0031100| organ regeneration IGF2R;PPARG GO:0007283| spermatogenesis IGF2R;SOD1;CNR1 19087:[DB14011 DB07498] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07498|4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance PPARG;CYP1A1;AKR1B1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0022900| electron transport chain CYP1A2;AKR1B1;GSR;IDO1 GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1;AKR1B1;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 19088:[DB14011 DB01946] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01946|3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione PDPK1;DMPK common genes common pathways GO:0032869| cellular response to insulin stimulus PPARG;PDPK1;PLA2G1B GO:0043524| negative regulation of neuron apoptosis SOD1;PDPK1 GO:0035556| intracellular signal transduction PLA2G1B;PDPK1 GO:0008016| regulation of heart contraction DMPK;CACNA1H GO:0006351| transcription, DNA-dependent PDPK1;PPARG GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;PDPK1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CHRNA7;DMPK;HTR2A;GPR12 GO:0006355| regulation of transcription, DNA-dependent PDPK1;PPARG 19089:[DB14011 DB09535] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09535|Octocrylene ESR1;ESR2 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TRPV1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;TRPV1;TRPV4;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR2;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;ESR2;PLA2G1B;CACNA1I;HTR1A;GPR55;ESR1;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1;TRPV1;TRPV4 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG GO:0006351| transcription, DNA-dependent ESR1;ESR2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 19090:[DB14011 DB01771] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01771|CRA_10991 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19091:[DB14011 DB04021] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04021|MF268 ACHE common genes common pathways GO:0008283| cell proliferation ACHE;HTR1A;GPX1;CYP1A1 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0009611| response to wounding CYP1A1;ACHE;GPX1 GO:0051262| protein tetramerization CAT;HMGCR;ACHE GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development ACHE;CACNA1H 19092:[DB14011 DB09045] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09045|Dulaglutide GLP1R common genes common pathways GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GLP1R;GPR18;PPARG GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;GLP1R;TRPV4;TRPV1 GO:0050796| regulation of insulin secretion CNR1;GLP1R GO:0045777| positive regulation of blood pressure GLP1R;CNR1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;GLP1R;TRPA1 GO:0008016| regulation of heart contraction GLP1R;CACNA1H GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GLP1R;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0007611| learning or memory GLP1R;CNR1;CHRNA7 19093:[DB14011 DB04505] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04505|8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0046677| response to antibiotic SOD1;CYP1A1;HSP90AA1 GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;PTGS2;OPRM1 GO:0009408| response to heat TRPV2;SOD1;TRPV3;TRPV1;HSP90AA1 GO:0009409| response to cold TRPA1;HSP90AA1;PPARG;TRPM8 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;HSP90AA1;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A 19094:[DB14011 DB07113] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07113|(2S)-6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2-(3,5-DIFLUOROPHENYL)-4-(3-METHOXYPROPYL)-2H-1,4-BENZOXAZIN-3(4H)-ONE REN common genes common pathways GO:0035902| response to immobilization stress CYP1A1;PPARG;REN;CYP1A2 GO:0001822| kidney development CAT;REN GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;REN;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;REN;ABCG2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1;REN GO:0051591| response to cAMP REN;AANAT GO:0048469| cell maturation PPARG;REN GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;REN;PPARG 19095:[DB14011 DB06307] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06307|Apoptone BCL2 common genes common pathways GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0030217| T cell differentiation BCL2;GPR18 GO:0007565| female pregnancy BCL2;IDO1 GO:0008631| induction of apoptosis by oxidative stress GPX1;BCL2;CYP1B1 GO:0043524| negative regulation of neuron apoptosis SOD1;BCL2 GO:0001503| ossification ALOX15;BCL2 GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;SOD1;BCL2 GO:0009314| response to radiation PTGS2;OPRM1;BCL2;CAT GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2;BCL2 GO:0001662| behavioral fear response VDAC1;BCL2;HTR1A GO:0030336| negative regulation of cell migration CYP1B1;BCL2 GO:0009791| post-embryonic development CYP1A2;BCL2 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;BCL2 GO:0009636| response to toxin BCL2;GPX1;CAT;CYP1A1;CYP1B1 GO:0008283| cell proliferation BCL2;HTR1A;GPX1;CYP1A1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;BCL2 GO:0010332| response to gamma radiation BCL2;GPX1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;BCL2 GO:0072593| reactive oxygen species metabolic process BCL2;SOD1 GO:0051384| response to glucocorticoid stimulus BCL2;PTGS2 GO:0035094| response to nicotine BCL2;CNR1;CHRNA7 GO:0007015| actin filament organization TRPV4;PLA2G1B;BCL2 GO:0007569| cell aging SOD1;BCL2 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;CAT;BCL2;CYP1A2;PTGS2;HTR2A;SOD1 GO:0034097| response to cytokine stimulus PTGS2;BCL2;AANAT GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;BCL2 GO:0001822| kidney development CAT;BCL2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;BCL2;PTGS2 GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0001657| ureteric bud development BCL2;CAT GO:0001541| ovarian follicle development BCL2;SOD1 GO:0006915| apoptotic process GPX1;BCL2;VDAC1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;BCL2;ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0043085| positive regulation of catalytic activity BCL2;SOD1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;BCL2;PTGS2;SOD1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;BCL2;GPR12;HTR2A;CHRNA7 GO:0048538| thymus development BCL2;SOD1 GO:0071456| cellular response to hypoxia OPRD1;BCL2;PTGS2;SLC29A1 GO:0010468| regulation of gene expression CYP1A2;BCL2 19096:[DB14011 DB09105] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09105|Asfotase Alfa S1PR1 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;S1PR1 GO:0007420| brain development ACAT1;S1PR1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;S1PR1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0019226| transmission of nerve impulse S1PR1;SOD1 GO:0001525| angiogenesis PTGS2;CYP1B1;S1PR1 GO:0031532| actin cytoskeleton reorganization TRPV4;S1PR1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger S1PR1;GPR18;GPR55 GO:0030595| leukocyte chemotaxis S1PR1;CNR2 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PPARG;GPR18;S1PR1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;S1PR1 GO:0007155| cell adhesion CYP1B1;S1PR1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;S1PR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;S1PR1 19097:[DB14011 DB09299] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09299|Tenofovir alafenamide pol;ABCB1 common genes common pathways GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0006810| transport ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2;TRPV2 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV1;VDAC1;ABCB1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 19098:[DB14011 DB12130] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes CYP3A5;CYP2C19 common pathways GO:0017144| drug metabolic process UGT1A3;CYP1A2;CYP3A4;CYP2C19;CYP2C8;CYP2D6;CYP2B6;CYP2C9;CYP1A1 GO:0036269| IDO1;ALK GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP17A1;CYP3A5;CYP1B1;CYP2B6;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0000187| activation of MAPK activity SOD1;ALK;CHRNA7;PLA2G1B GO:0002933| CYP2C8;CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP1B1;CYP2B6;CYP1A1;CYP2C9;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0042127| regulation of cell proliferation ALK;PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP2B6;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C8 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2C8;CYP1B1 GO:0007420| brain development ACAT1;ALK GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;ALK;HTR1A;GPR55;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0070989| oxidative demethylation CYP3A5;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0008283| cell proliferation GPX1;ALK;HTR1A;CYP1A1 GO:0007399| nervous system development ALK;SMPD1;GLRB GO:0008152| metabolic process ACAT1;UGT1A3;SMPD1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP2B6;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;ALK GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C8;CYP2C9;CYP2B6 19099:[DB14011 DB06325] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06325|Pegpleranib PDGFB common genes common pathways GO:0007507| heart development PDGFB;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;PDGFB GO:0010629| negative regulation of gene expression PDGFB;OPRD1 GO:0072593| reactive oxygen species metabolic process SOD1;PDGFB GO:0051781| positive regulation of cell division PDGFB;CAT GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;PDGFB GO:0045740| positive regulation of DNA replication PLA2G1B;PDGFB GO:0090280| positive regulation of calcium ion import TRPV2;TRPV3;PDGFB GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;PDGFB;CHRNA7 GO:0002576| platelet degranulation SOD1;PDGFB GO:0048661| positive regulation of smooth muscle cell proliferation PDGFB;PTGS2;HMGCR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PDGFB GO:0060326| cell chemotaxis PDGFB;ABCC1 GO:0045893| positive regulation of transcription, DNA-dependent PDGFB;PPARG GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1;PDGFB GO:0009611| response to wounding PDGFB;GPX1;CYP1A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PDGFB;CAT GO:0010628| positive regulation of gene expression TRPV4;PDGFB GO:0043406| positive regulation of MAP kinase activity HTR2A;PDGFB GO:0045892| negative regulation of transcription, DNA-dependent PDGFB;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;GPR55;PDGFB;HTR2A;OPRM1;HMGCR;CHRNA7 19100:[DB14011 DB07286] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07286|BMS-564929 AR common genes common pathways GO:0007283| spermatogenesis AR;SOD1;CNR1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;AR;TRPV2 GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;AR GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;OPRM1;PTGS2 GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;AR;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG 19101:[DB14011 DB04620] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04620|Cycloleucine GRIN1 common genes common pathways GO:0043065| positive regulation of apoptotic process GRIN1;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0045471| response to ethanol HMGCR;OPRM1;GRIN1;CNR1;SOD1;CAT GO:0019233| sensory perception of pain TRPV1;TRPA1;GRIN1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:0008542| visual learning HMGCR;GRIN1 GO:0001964| startle response GLRA1;GLRB;GRIN1 GO:0006816| calcium ion transport CACNA1H;GRIN1;TRPV3;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I GO:0043524| negative regulation of neuron apoptosis SOD1;GRIN1 GO:0065009| regulation of molecular function GRIN1;TRPV1 GO:0007613| memory CHRNA7;CNR1;HTR2A;GRIN1;PTGS2 GO:0043576| regulation of respiratory gaseous exchange GLRA1;GRIN1 GO:0001975| response to amphetamine SOD1;GRIN1;CNR2 GO:0006812| cation transport TRPM8;GRIN1 GO:0008344| adult locomotory behavior GRIN1;OPRD1 GO:0006811| ion transport TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;GRIN1;GLRA3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PLA2G1B;PPARG GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;CHRNA7;SLC29A1;GLRA3;GRIN1;OPRM1 GO:0007612| learning VDAC1;PTGS2;GRIN1 GO:0010524| positive regulation of calcium ion transport into cytosol GRIN1;PLA2G1B GO:0043523| regulation of neuron apoptosis GPX1;GRIN1 GO:0007611| learning or memory GRIN1;CNR1;CHRNA7 GO:0043278| response to morphine CNR1;GRIN1;OPRM1 GO:0050905| neuromuscular process GLRA1;GLRB;GRIN1 GO:0006874| cellular calcium ion homeostasis CHRNA7;GRIN1;HTR2A;GPR12;TRPV4;TRPM8 GO:0042391| regulation of membrane potential GRIN1;CACNA1H;GLRB;GLRA1;CACNA1G GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN1 19102:[DB14011 DB07632] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07632|5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide CA2 common genes common pathways GO:0010033| response to organic substance CA2;PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0001822| kidney development CA2;CAT GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 19103:[DB14011 DB01332] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways GO:0098656| SLC22A6;VDAC1;SLC22A8 GO:0006811| ion transport SLC15A1;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA3;SLC22A8;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0009636| response to toxin SLC22A8;CAT;GPX1;CYP1A1;CYP1B1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0006810| transport TRPV2;ABCC1;SLC15A1;TRPV1;CACNA1I;ABCG2 GO:0055085| transmembrane transport SLC22A8;TRPV3;CACNA1H;TRPV2;TRPA1;SLC15A1;ABCC1;CACNA1G;SLC22A6;TRPM8;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1 19104:[DB14011 DB07344] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;MCAT;PLA2G1B GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;CYP2C9;PPARG;PTGS1;NAAA;GPX1;MCAT;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0008152| metabolic process ACAT1;MCAT;SMPD1 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1;MCAT GO:0006635| fatty acid beta-oxidation ACAT1;MCAT 19105:[DB14011 DB03923] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03923|Feruloyl Coenzyme A COMTD1 common genes common pathways GO:0032259| methylation COMTD1;CYP1A2 19106:[DB14011 DB06688] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06688|Sipuleucel-T ACPP common genes common pathways GO:0043312| neutrophil degranulation ACPP;CAT;ALOX5 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ACPP GO:0051289| protein homotetramerization TRPM8;TRPV1;TRPA1;CRYZ;ACPP;CAT 19107:[DB14011 DB07394] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07394|AUROVERTIN B ATP5B common genes common pathways GO:0001649| osteoblast differentiation CAT;ATP5B GO:0006811| ion transport ATP5B;CACNA1G;GLRA1;TRPA1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0006629| lipid metabolic process ATP5B;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1 GO:0001525| angiogenesis CYP1B1;ATP5B;PTGS2 19108:[DB14011 DB05192] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05192|MB07811 THRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;THRB GO:0006367| transcription initiation from RNA polymerase II promoter THRB;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;THRB;TRPV1 GO:0045892| negative regulation of transcription, DNA-dependent THRB;PPARG GO:0007605| sensory perception of sound GPX1;SOD1;THRB GO:0008016| regulation of heart contraction THRB;CACNA1H GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;THRB GO:0006351| transcription, DNA-dependent PPARG;THRB 19109:[DB14011 DB09341] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09341|Dextrose, unspecified form HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1 common genes common pathways GO:0032869| cellular response to insulin stimulus PLA2G1B;SLC2A4;PPARG;GCK GO:0050796| regulation of insulin secretion SLC2A1;GCK;CNR1;SLC2A2 GO:0042908| xenobiotic transport ABCG2;ABCC1;SLC2A1 GO:0006811| ion transport TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;SLC5A1;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0032868| response to insulin stimulus TRPV4;CAT;AANAT;SLC2A1 GO:0006970| response to osmotic stress SLC2A1;TRPV4 GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;SLC2A4 GO:0050873| brown fat cell differentiation SLC2A4;PTGS2 GO:0008152| metabolic process GCK;ACAT1;SMPD1;HK1 GO:0071260| cellular response to mechanical stimulus SLC2A1;PTGS2 GO:0046415| urate metabolic process ABCG2;SLC2A9 GO:0007565| female pregnancy IDO1;SLC2A1 GO:0071456| cellular response to hypoxia SLC2A4;PTGS2;OPRD1;SLC29A1 GO:0042593| glucose homeostasis TRPV4;SLC2A4;PPARG;GCK;CNR1 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;SLC2A10;TRPV1;SLC2A2;ABCG2;TRPM8;CACNA1G;ABCC1;SLC2A4;TRPA1;TRPV2;SLC2A6;SLC2A7;SLC5A1;SLC2A11;CACNA1H;SLC2A8;SLC2A1;TRPV3;SLC2A12;SLC2A9;SLC2A3 GO:0071470| cellular response to osmotic stress TRPV4;SLC2A4 GO:0001666| response to hypoxia SLC2A8;CAT;CHRNA7;CYP1A1 GO:0071356| cellular response to tumor necrosis factor SLC2A4;TRPV1 GO:0015758| glucose transport PLA2G1B;SLC2A10;SLC2A2;SLC2A4;SLC5A1;SLC2A1;SLC2A8;SLC2A9;SLC2A12;SLC2A3 GO:0070509| calcium ion import CACNA1G;CACNA1I;TRPV4;CACNA1H;GCK GO:0043312| neutrophil degranulation SLC2A3;CAT;ALOX5 19110:[DB14011 DB04519] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0019216| regulation of lipid metabolic process HMGCR;PPARA;CNR1;PPARG;CYP1A1 GO:0098656| SLC22A6;VDAC1;SLC22A8 GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0032868| response to insulin stimulus TRPV4;PPARA;CAT;AANAT GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;SLC22A8;TRPV2;CHRNA7;SLC22A11 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;PPARA;NAAA;PTGS1;GPX1 GO:0007507| heart development PPARG;PPARA GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0006351| transcription, DNA-dependent PPARG;PPARA GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0001666| response to hypoxia CYP1A1;PPARA;CAT;CHRNA7 GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0055085| transmembrane transport SLC22A11;TRPV2;SLC22A8;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;TRPA1;SLC22A6;CACNA1G;ABCC1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PPARA GO:0042060| wound healing ALOX15;OPRM1;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0006631| fatty acid metabolic process PTGS1;PPARA;PTGS2;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG 19111:[DB14011 DB03664] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03664|UP5 CMPK1 common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;CMPK1 GO:0015949| nucleobase-containing small molecule interconversion GSR;CMPK1 19112:[DB14011 DB08088] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;AR GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HMGCR;PTGS2;HTR2A;HTR1A GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;AR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport AR;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0007283| spermatogenesis AR;SOD1;CNR1 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;AR;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;AR GO:0007548| sex differentiation CYP17A1;AR 19113:[DB14011 DB08740] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08740|CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE CTSD common genes common pathways GO:0043312| neutrophil degranulation CTSD;ALOX5;CAT 19114:[DB14011 DB07934] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07934|[[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE F2 common genes common pathways GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;F2;GPR18;PPARG GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;F2 19115:[DB14011 DB06650] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06650|Ofatumumab MS4A1 common genes common pathways 19116:[DB14011 DB03456] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03456|N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide CTSK common genes common pathways GO:0045453| bone resorption GPR55;CTSK GO:1903146| CTSK;VDAC1 19117:[DB14011 DB07310] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07310|(5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(trifluoromethyl)-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B1 GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1A1;CYP2C9;HSD11B1;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0030324| lung development CYP1A2;HSD11B1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;HSD11B1;CAT GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9;HSD11B1;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR 19118:[DB14011 DB04409] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;FGF1;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0051781| positive regulation of cell division FGF1;CAT GO:0008283| cell proliferation FGF1;HTR1A;GPX1;CYP1A1 GO:0001525| angiogenesis PTGS2;FGF1;CYP1B1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;FGF1 GO:0034605| cellular response to heat TRPV4;TRPV1;FGF1;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF1 GO:0045766| positive regulation of angiogenesis FGF1;CHRNA7;CYP1B1 GO:0000187| activation of MAPK activity CHRNA7;FGF1;SOD1;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;FGF1;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;PPARG;PLA2G1B GO:0030324| lung development CYP1A2;FGF1 GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;GPX1 19119:[DB14011 DB02509] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02509|Farnesol MAOB;NR1H4;MAOB common genes common pathways GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;NR1H4;CYP1B1 GO:0009636| response to toxin CYP1B1;MAOB;CYP1A1;GPX1;CAT GO:0010269| response to selenium ion GPX1;MAOB GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;NR1H4;OPRD1 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;NR1H4;PTGS2;CNR2 GO:0045471| response to ethanol MAOB;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0043401| steroid hormone mediated signaling pathway NR1H4;PPARG GO:0006351| transcription, DNA-dependent NR1H4;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NR1H4 GO:0007043| cell-cell junction assembly TRPV4;NR1H4 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1;MAOB GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7;NR1H4 GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1;NR1H4 GO:0002376| immune system process NR1H4;IDO1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1H4 GO:0050728| negative regulation of inflammatory response CNR2;NR1H4 GO:0055114| oxidation-reduction process GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;MAOB;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;MAOB GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1H4 GO:0022900| electron transport chain IDO1;GSR;MAOB;CYP1A2 GO:0045087| innate immune response PPARG;NR1H4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR1H4 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;NR1H4;PTGS2;CAT;GPX1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MAOB;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 19120:[DB14011 DB08560] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes PPARG common pathways GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;GPR18;PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG 19121:[DB14011 DB07917] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways GO:0006631| fatty acid metabolic process PTGS1;HPGDS;PTGS2;ALOX15 GO:0007626| locomotory behavior HPGDS;OPRM1;SOD1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1;HPGDS GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;PTGS1;NAAA;GPX1;HPGDS;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0006693| prostaglandin metabolic process HPGDS;PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1;HPGDS GO:0006633| fatty acid biosynthetic process PLA2G1B;HPGDS;PTGS1;PTGS2 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;HPGDS;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B 19122:[DB14011 DB03384] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03384|Fica CASP7 common genes common pathways GO:0006915| apoptotic process GPX1;CASP7;VDAC1 19123:[DB14011 DB07630] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07630|N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 19124:[DB14011 DB00931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00931|Metacycline ALB common genes common pathways GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR;ALB GO:0001895| retina homeostasis ALB;SOD1 19125:[DB14011 DB05233] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05233|AP1081 ESR1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;ESR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0032355| response to estradiol stimulus CAT;ESR1;CYP1A2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG 19126:[DB14011 DB00903] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0008217| regulation of blood pressure SOD1;ATP1A1;PTGS2;PTGS1;PPARG GO:0098656| SLC22A6;VDAC1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0006749| glutathione metabolic process GSTA2;SOD1;GPX1;GSTP1;GSR GO:0001895| retina homeostasis SOD1;ALB GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0009636| response to toxin CYP1B1;GSTP1;CYP1A1;CAT;GPX1 GO:0006811| ion transport TRPV3;CACNA1H;ATP1A1;GLRA3;TRPV2;CHRNA7;SLC12A1;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8 GO:0001649| osteoblast differentiation CAT;LEF1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B GO:0071345| cellular response to cytokine stimulus LEF1;TRPV1 GO:1904706| GSTP1;PPARG GO:1902476| GLRA3;SLC12A1;GLRA1;GLRB GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;LEF1;PTGS2 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;GSTP1;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0008152| metabolic process ACAT1;GSTA2;GSTP1;SMPD1 GO:0006351| transcription, DNA-dependent LEF1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;LEF1 GO:0045471| response to ethanol GSTP1;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;LEF1 GO:0045892| negative regulation of transcription, DNA-dependent LEF1;PPARG GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0010628| positive regulation of gene expression LEF1;TRPV4 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0030855| epithelial cell differentiation PPARG;VDAC1;GSTA2 GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC12A1;TRPV2;TRPA1;CACNA1G;SLC22A6;ABCC1;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1 GO:0086002| ATP1A1;CACNA1G GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;SLC12A1;CHRNA7;GLRA3;ATP1A1 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;ALB;GSR;GSTP1 GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;SLC12A1;TRPV2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;GSTP1 GO:0060326| cell chemotaxis ABCC1;LEF1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;LEF1 GO:0006355| regulation of transcription, DNA-dependent PPARG;LEF1 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;ATP1A1;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0043312| neutrophil degranulation GSTP1;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;LEF1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;GSTA2 GO:0043066| negative regulation of apoptotic process GSTP1;ALB;GPX1;CAT;HMGCR;PTGS2;LEF1;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;LEF1;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter LEF1;PLA2G1B;PPARG GO:0002576| platelet degranulation ALB;SOD1 GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;GSTP1;GSR GO:0000302| response to reactive oxygen species GSTP1;GPX1;CAT;SOD1 19127:[DB14011 DB07789] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;TRPV1;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process PLK1;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0008283| cell proliferation HTR1A;GPX1;PLK1;CYP1A1 19128:[DB14011 DB06945] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways 19129:[DB14011 DB02855] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02855|N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline CTSB common genes common pathways GO:0046718| entry of virus into host cell HTR2A;CTSB GO:0046697| decidualization CTSB;PTGS2 GO:0030855| epithelial cell differentiation CTSB;VDAC1;PPARG GO:0043312| neutrophil degranulation CTSB;ALOX5;CAT 19130:[DB14011 DB00856] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00856|Chlorphenesin CYP2B;CYP19A1;CYP3A4;XDH;PTGS2;BCHE common genes CYP3A4;PTGS2 common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| PTGS2;CAT;PTGS1;GPX1;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0007568| aging CYP1A1;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:1902219| PTGS2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0071284| cellular response to lead ion PTGS2 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;CYP19A1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0055114| oxidation-reduction process SOD1;CYP3A4;XDH;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP19A1;CYP1A1;CYP2C9;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0022900| electron transport chain CYP19A1;IDO1;GSR;XDH;CYP1A2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;BCHE;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;BCHE;PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006919| activation of caspase activity XDH;PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0033280| response to vitamin D PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0007595| lactation SLC29A1;XDH GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0010942| positive regulation of cell death PTGS2 GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0010629| negative regulation of gene expression XDH;OPRD1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 19131:[DB14011 DB02328] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02328|2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid CTH common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;CTH;SOD1;GPX1;CAT GO:0051289| protein homotetramerization CAT;CTH;TRPV1;TRPM8;CRYZ;TRPA1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CTH;CAT 19132:[DB14011 DB04491] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04491|Diisopropylphosphono Group CFB;DPP4 common genes common pathways GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045087| innate immune response PPARG;CFB GO:0007155| cell adhesion CYP1B1;DPP4 GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 GO:0002376| immune system process CFB;IDO1 GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 19133:[DB14011 DB01089] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01089|Deserpidine SLC18A2 common genes common pathways GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC18A2;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8 GO:0007626| locomotory behavior OPRM1;SOD1;SLC18A2 GO:0007269| neurotransmitter secretion SLC18A2;NAAA GO:0009791| post-embryonic development SLC18A2;CYP1A2 GO:0009636| response to toxin GPX1;CAT;SLC18A2;CYP1B1;CYP1A1 GO:0001975| response to amphetamine CNR2;SOD1;SLC18A2 GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;SLC18A2;GLRA3;HTR2A;OPRM1;OPRD1 19134:[DB14011 DB13166] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13166|Zofenopril ACE common genes common pathways GO:0007283| spermatogenesis ACE;CNR1;SOD1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0001822| kidney development ACE;CAT GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;ACE;PTGS1 GO:0060047| heart contraction GPX1;ACE;SOD1 GO:0050482| arachidonic acid secretion PLA2G1B;ACE 19135:[DB14011 DB07363] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07363|THIOPHENE-2,5-DISULFONIC ACID 2-AMIDE-5-(4-METHYL-BENZYLAMIDE) CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CA2;SOD1;PTGS2;CYP1A2 19136:[DB14011 DB00861] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00861|Diflunisal PTGS2;PTGS1;UGT1A8;UGT1A9;TTR;ALB;SLC22A6 common genes PTGS2;PTGS1 common pathways GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0002576| platelet degranulation SOD1;ALB GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;UGT1A8;PTGS1;PTGS2 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009804| coumarin metabolic process UGT1A8;CYP1A1;CYP2D6 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0009750| response to fructose stimulus PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:1902219| PTGS2 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;UGT1A8;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0097756| PTGS2;HMGCR GO:0007568| aging NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT;CYP1A1 GO:0006810| transport TTR;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0051260| protein homooligomerization SLC22A6;GLRA1;ACAT1;GLRA3 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| ALB;GSR;PTGS2;CAT;GPX1;PTGS1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9;CYP1A1;UGT1A8;UGT1A9 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;SLC22A6;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0008152| metabolic process ACAT1;UGT1A9;UGT1A8;SMPD1 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;UGT1A9;CYP2C9 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0042572| retinol metabolic process CYP1B1;TTR GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;UGT1A9;CNR1;HMGCR GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001895| retina homeostasis ALB;SOD1 GO:0042633| hair cycle PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0098656| VDAC1;SLC22A6 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG 19137:[DB14011 DB00995] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways GO:0034599| cellular response to oxidative stress GSR;PRDX5;SOD1;GPX1;CAT GO:0002576| platelet degranulation SOD1;ALB GO:0009615| response to virus CYP1A1;IKBKB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;IKBKB GO:0043066| negative regulation of apoptotic process ALB;SOD1;IKBKB;PRDX5;PTGS2;HMGCR;CAT;GPX1 GO:0045087| innate immune response IKBKB;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IKBKB GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;PRDX5;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;PTGS1;GPX1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;PRDX5;SOD1 GO:0098869| ALB;GSR;CAT;GPX1;PTGS1;PRDX5;PTGS2 GO:0006915| apoptotic process PRDX5;GPX1;VDAC1 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;PRDX5 GO:0071356| cellular response to tumor necrosis factor IKBKB;TRPV1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;PRDX5;GPX1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;IKBKB GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS2;CNR2;IKBKB;PRDX5;ALOX5;PTGS1 GO:0045454| cell redox homeostasis GSR;GPX1;PRDX5 GO:0001895| retina homeostasis SOD1;ALB 19138:[DB14011 DB00108] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;FCGR2B;ALOX5;PTGS1;PTGS2;CNR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;ICAM1;CAT GO:0016032| viral reproduction ICAM1;FCGR2B;VDAC1;HTR2A GO:0006955| immune response C1QC;FCGR3A;FCGR2C;OPRD1;CNR2;FCGR3B;FCGR2B;C1R;FCGR1A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ICAM1;HTR2A GO:0045471| response to ethanol ICAM1;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0071312| cellular response to alkaloid ICAM1;TRPV1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;ICAM1;TRPA1;CYP1A1;PPARG GO:0032868| response to insulin stimulus AANAT;CAT;ICAM1;TRPV4 GO:0002438| acute inflammatory response to antigenic stimulus ICAM1;OPRM1 GO:1902042| ICAM1;GPX1 GO:0001975| response to amphetamine SOD1;CNR2;ICAM1 GO:0071345| cellular response to cytokine stimulus ITGA4;TRPV1 GO:0046718| entry of virus into host cell HTR2A;ICAM1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;ICAM1 GO:0007165| signal transduction SMPD1;PPARG;FCGR2B;GPR18;PLA2G1B;CACNA1I;FCGR1A;OPRM1;CNR2;FCGR2C;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;ICAM1;SMPD1 GO:0051926| negative regulation of calcium ion transport PTGS2;ICAM1 GO:0007569| cell aging SOD1;ICAM1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;ICAM1;CYP1A1;IDO1 GO:0030838| positive regulation of actin filament polymerization ICAM1;ALOX15 GO:0071333| cellular response to glucose stimulus ICAM1;SLC29A1 GO:0046330| positive regulation of JNK cascade TRPV4;FCGR2B GO:0007155| cell adhesion ICAM1;CYP1B1;ITGA4 GO:0045087| innate immune response FCGR1A;PPARG;C1QB;C1R;C1QA;C1QC GO:0043312| neutrophil degranulation CAT;ALOX5;FCGR3B;FCGR2A GO:0043200| response to amino acid stimulus GLRA3;GLRB;ICAM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4;ICAM1 GO:0001541| ovarian follicle development ICAM1;SOD1 GO:0046688| response to copper ion ICAM1;SOD1;AANAT GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;ICAM1 GO:0071356| cellular response to tumor necrosis factor TRPV1;ICAM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;ICAM1 GO:0002376| immune system process C1QA;C1QC;FCGR2A;FCGR1A;IDO1;C1QB;C1R GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;ICAM1 GO:0007605| sensory perception of sound ICAM1;SOD1;GPX1 19139:[DB14011 DB11858] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;CYSLTR2;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0045766| positive regulation of angiogenesis CYSLTR2;CHRNA7;CYP1B1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CYSLTR1;CNR2;OPRM1;OPRD1;CYSLTR2;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0007218| neuropeptide signaling pathway GLRA3;CYSLTR2;OPRD1;OPRM1;CYSLTR1;GLRB;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CYSLTR1;OPRM1;OPRD1;CYSLTR2;HTR2A GO:0007165| signal transduction CYSLTR1;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CYSLTR2;GPR12;CNR1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration CYSLTR1;TRPV1;TRPV4;OPRM1;HTR2A GO:0010942| positive regulation of cell death PTGS2;CYSLTR2 GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;CYSLTR1;TRPV1;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0006955| immune response OPRD1;CNR2;CYSLTR2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;CYSLTR1;TRPA1 19140:[DB14011 DB14132] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes CYP1A2 common pathways GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;ADORA2A;TRPA1;CYP1A1;PPARG GO:0006355| regulation of transcription, DNA-dependent ADORA2A;PPARG GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0050728| negative regulation of inflammatory response ADORA2A;CNR2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;GLRA1;ADORA2A;TRPV1;GLRB GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0007626| locomotory behavior ADORA2A;SOD1;OPRM1 GO:0042311| vasodilation GPX1;ADORA2A GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0006915| apoptotic process GPX1;ADORA2A;VDAC1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0031000| response to caffeine PPARG;ADORA2A GO:0010468| regulation of gene expression CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PPARG;ADORA2A;GPR18 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;ADORA2A GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0043524| negative regulation of neuron apoptosis SOD1;ADORA2A GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0007600| sensory perception TRPV2;OPRM1;ADORA2A GO:0006954| inflammatory response ADORA2A;ALOX15;IDO1;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADORA2A;CNR1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;ADORA2A GO:0042755| eating behavior OPRM1;OPRD1;ADORA2A GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;ADORA2A;PPARG GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0001975| response to amphetamine ADORA2A;SOD1;CNR2 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;ADORA2A;SMPD1 GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 19141:[DB14011 DB07165] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07165|N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE F2 common genes common pathways GO:0061844| F2;PLA2G1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 19142:[DB14011 DB07257] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07257|4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione WEE1 common genes common pathways 19143:[DB14011 DB07716] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07716|(4Z)-2,8:7,12:11,15:14,18:17,22-PENTAANHYDRO-4,5,6,9,10,13,19,20,21-NONADEOXY-D-ARABINO-D-ALLO-D-ALLO-DOCOSA-4,9,20-TRIENITOL IGKC common genes common pathways GO:0045087| innate immune response PPARG;IGKC GO:0002376| immune system process IDO1;IGKC GO:0006955| immune response IGKC;CNR2;OPRD1 GO:0001895| retina homeostasis SOD1;IGKC 19144:[DB14011 DB09070] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0007565| female pregnancy STS;IDO1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0008152| metabolic process SMPD1;HSD3B1;HSD3B2;STS;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;SULT1A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;STS;CYP1A2 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;STS;CYP1A2;PTGS2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;SULT1A1;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0006702| androgen biosynthetic process HSD3B2;HSD3B1;CYP17A1 GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;ESR1;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;ESR1;OPRM1 GO:0009308| amine metabolic process CYP1A1;SULT1A1 GO:0006694| steroid biosynthetic process HSD3B2;HMGCR;CYP17A1;HSD3B1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0008210| estrogen metabolic process CYP1B1;SULT1A1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0055114| oxidation-reduction process HMGCR;HSD3B2;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;HSD3B1;CYP3A5;ALOX15;CYP17A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;ESR1 GO:0009812| flavonoid metabolic process CYP1A1;SULT1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD3B1;HSD3B2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;STS;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;SULT1A1;CYP2C9;CYP1A1 GO:0006687| glycosphingolipid metabolic process SMPD1;STS 19145:[DB14011 DB09479] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09479|Rubidium Rb-82 FXYD2;ATP1A1;ATP1B1;ATP1B2;ATP1B3;ATP1A4;ATP1A2;ATP1A3 common genes common pathways GO:0008542| visual learning ATP1A3;ATP1A2;HMGCR GO:0071260| cellular response to mechanical stimulus ATP1A2;PTGS2;ATP1A1 GO:0006811| ion transport CACNA1H;TRPV3;ATP1A4;ATP1A1;GLRA3;TRPV2;ATP1B2;CHRNA7;ATP1A2;CACNA1G;ATP1B1;FXYD2;ATP1A3;GLRA1;TRPA1;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;ATP1B3;TRPM8 GO:0008344| adult locomotory behavior ATP1A2;ATP1A3;OPRD1 GO:0051966| regulation of synaptic transmission, glutamatergic ATP1A2;CNR1 GO:0008217| regulation of blood pressure PTGS2;SOD1;ATP1A1;PTGS1;ATP1A2;PPARG GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A;ATP1A3 GO:0042493| response to drug CAT;CYP1A2;PTGS2;ATP1A1;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;ATP1A3;TRPA1;CYP1A1;PPARG GO:0035094| response to nicotine CNR1;CHRNA7;ATP1A2 GO:0042127| regulation of cell proliferation FXYD2;PTGS2;PTGS1 GO:0051481| reduction of cytosolic calcium ion concentration ATP1A2;OPRM1 GO:0030317| sperm motility ATP1A4;CACNA1I GO:0071300| cellular response to retinoic acid PPARG;ATP1A3 GO:0007155| cell adhesion ATP1B1;CYP1B1;ATP1B2 GO:0034220| ion transmembrane transport ATP1A4;ATP1A1;GLRA3;ATP1B2;CHRNA7;ATP1A2;ATP1B1;ATP1A3;GLRA1;TRPA1;FXYD2;TRPV1;GLRB;ATP1B3 GO:0086002| ATP1A1;CACNA1G GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1;ATP1A2 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;ATP1B1 GO:0007283| spermatogenesis ATP1A4;CNR1;SOD1 GO:0010468| regulation of gene expression CYP1A2;ATP1B1 GO:0006810| transport ATP1B2;TRPV2;ATP1B3;ABCG2;CACNA1I;TRPV1;FXYD2;ABCC1 GO:0006874| cellular calcium ion homeostasis ATP1B1;TRPM8;TRPV4;GPR12;HTR2A;CHRNA7 GO:0042391| regulation of membrane potential CACNA1H;ATP1A4;GLRB;CACNA1G;GLRA1 19146:[DB14011 DB02462] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02462|Thiocoumarin NOS2 common genes common pathways GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0050796| regulation of insulin secretion NOS2;CNR1 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NOS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;IDO1;NOS2;CYP1A1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ;NOS2 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;NOS2 19147:[DB14011 DB04509] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04509|N-Methylnaloxonium CES1;CES1 common genes common pathways GO:0030855| epithelial cell differentiation CES1;VDAC1;PPARG GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0009636| response to toxin CES1;GPX1;CAT;CYP1A1;CYP1B1 GO:0008152| metabolic process SMPD1;ACAT1;CES1 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 19148:[DB14011 DB02395] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02395|3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol NQO1 common genes common pathways GO:0007584| response to nutrient PPARG;NQO1;HMGCR;CNR1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;NQO1 GO:0009636| response to toxin CYP1B1;CYP1A1;NQO1;CAT;GPX1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;CYP1A1;PPARG;NQO1;TRPA1 GO:0006809| nitric oxide biosynthetic process NQO1;CYP1B1 GO:0019430| removal of superoxide radicals SOD1;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0045471| response to ethanol NQO1;CAT;OPRM1;HMGCR;SOD1;CNR1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1;NQO1 GO:0032355| response to estradiol stimulus NQO1;CAT;PTGS2;CYP1A2 GO:0007568| aging HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT;NQO1;CYP1A1 GO:0006801| superoxide metabolic process NQO1;SOD1 GO:0055114| oxidation-reduction process CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;NQO1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;NQO1 19149:[DB14011 DB00964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways GO:0045777| positive regulation of blood pressure CNR1;ADRA2B GO:0008285| negative regulation of cell proliferation PPARG;ADRA1A;CYP1B1;PTGS2;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV1;ADRA1A;TRPV4 GO:0050796| regulation of insulin secretion CNR1;ADRA2A GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0007165| signal transduction PPARG;GPR18;SMPD1;ADRA2A;ADRA1A;CACNA1I;PLA2G1B;GPR55;HTR1A;ADRA2B;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;ADRA1A GO:0001819| positive regulation of cytokine production ADRA2A;SOD1 GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0007565| female pregnancy IDO1;ADRA2B GO:0035556| intracellular signal transduction PLA2G1B;ADRA1A GO:0006915| apoptotic process GPX1;VDAC1;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;SOD1;CHRNA7;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ADRA1A;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A GO:0007202| activation of phospholipase C activity ADRA1A;HTR2A;GPR55 GO:0007568| aging CYP1A1;ADRA1A;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;ADRA2B;ADRA1A;ADRA2A;PPARG;GPR18 GO:0042593| glucose homeostasis CNR1;TRPV4;ADRA2A;PPARG GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug ABCG2;ADRA1A;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;ADRA1A GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;ADRA2A 19150:[DB14011 DB00487] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes CYP1A2 common pathways GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;PLA2G1B GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP2C9;CYP1A1;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;PTGS2;CYP1A2 GO:0048511| rhythmic process AANAT;PPARG;TOP2A GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;TOP2A;CYP1B1;TRPV1;IDO1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 19151:[DB14011 DB04549] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04549|4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide CA2 common genes common pathways GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1;CA2 19152:[DB14011 DB02861] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02861|4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide CA2 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CA2;TRPA1;CYP1A1;PPARG GO:0001822| kidney development CAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 19153:[DB14011 DB07154] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001666| response to hypoxia DPP4;CYP1A1;CHRNA7;CAT GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0007155| cell adhesion CYP1B1;DPP4 19154:[DB14011 DB13881] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13881|Tisagenlecleucel CD19 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CD19;TRPV1;TRPA1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;CD19 19155:[DB14011 DB04233] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04233|(Hydroxyethyloxy)Tri(Ethyloxy)Octane CLPS;PNLIP;RHO common genes common pathways GO:0050896| response to stimulus TRPM8;TRPA1;RHO GO:0001523| retinoid metabolic process PNLIP;NAPEPLD;CLPS;RHO GO:0007601| visual perception GLRB;CYP1B1;RHO;GLRA1;CRYZ GO:0007165| signal transduction GPR18;PPARG;SMPD1;RHO;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PNLIP;NAAA;PTGS1;GPX1;CLPS;CYP2C9;PPARG;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0016042| lipid catabolic process NAPEPLD;PNLIP;CLPS;PLA2G1B;DAGLA GO:0009416| response to light stimulus AANAT;RHO GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;RHO;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0043085| positive regulation of catalytic activity SOD1;CLPS GO:0032094| response to food OPRM1;CYP1A1;CLPS 19156:[DB14011 DB03703] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03703|Cyclohexanol ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ;ADH1B;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR 19157:[DB14011 DB02744] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02744|RPR131247 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19158:[DB14011 DB13132] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13132|Artemisinin CYP2B6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2B6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP2B6;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2B6;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP2B6;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP2B6;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP2B6;CYP1B1;CYP2C19 19159:[DB14011 DB04852] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04852|Implitapide MTTP common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;MTTP;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 19160:[DB14011 DB05920] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05920|RTA 744 TOP2A common genes common pathways GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TOP2A;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0042752| regulation of circadian rhythm PPARG;TOP2A 19161:[DB14011 DB08163] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08163|5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine AMD1 common genes common pathways 19162:[DB14011 DB03894] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03894|N-Propargyl-1(S)-Aminoindan MAOB;MAOB common genes common pathways GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;MAOB;SOD1;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;MAOB;CYP1A1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;MAOB;TRPA1;CYP1A1;PPARG GO:0022900| electron transport chain GSR;IDO1;MAOB;CYP1A2 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CRYZ;MAOB GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0010269| response to selenium ion MAOB;GPX1 GO:0009636| response to toxin CYP1A1;MAOB;CYP1B1;CAT;GPX1 GO:0045471| response to ethanol MAOB;CAT;HMGCR;OPRM1;CNR1;SOD1 19163:[DB14011 DB05938] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05938|Edonerpic APP common genes common pathways GO:0008344| adult locomotory behavior APP;OPRD1 GO:0061844| PLA2G1B;APP GO:0032930| positive regulation of superoxide anion generation APP;SOD1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;APP;PPARG;CYP1B1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;APP GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2;APP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRM1;OPRD1 GO:0040014| regulation of multicellular organism growth APP;SOD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;APP GO:1900273| CHRNA7;APP GO:1902004| APP;CHRNA7 GO:0001934| positive regulation of protein phosphorylation APP;CHRNA7 GO:0071320| cellular response to cAMP APP;AANAT GO:0007268| synaptic transmission CACNA1G;APP;GLRA1;GLRB;VDAC1;OPRM1;OPRD1;HTR2A;GLRA3 GO:0010629| negative regulation of gene expression APP;OPRD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0008542| visual learning HMGCR;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;APP;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0001774| microglial cell activation APP;TRPV1 GO:0007399| nervous system development SMPD1;APP;GLRB GO:1990090| APP;TRPV1 GO:0043065| positive regulation of apoptotic process SMPD1;APP;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;APP;TRPV4;ALOX15 GO:0000187| activation of MAPK activity APP;PLA2G1B;SOD1;CHRNA7 GO:0006915| apoptotic process GPX1;VDAC1;APP GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0051262| protein tetramerization APP;CAT;HMGCR GO:0010628| positive regulation of gene expression TRPV4;APP GO:0010468| regulation of gene expression APP;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;PPARG;GPR18;APP GO:0098815| APP;CHRNA7 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;APP GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;APP;OPRM1;PTGS2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;APP GO:0019731| antibacterial humoral response APP;PLA2G1B GO:0050808| synapse organization CHRNA7;APP GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0051897| positive regulation of protein kinase B signaling cascade APP;GPX1 GO:1905906| APP;CHRNA7 GO:0046330| positive regulation of JNK cascade APP;TRPV4 GO:0007612| learning VDAC1;APP;PTGS2 GO:0008203| cholesterol metabolic process HMGCR;CAT;APP GO:0007611| learning or memory APP;CNR1;CHRNA7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;PPARG;TRPV1;TRPV4 GO:0007155| cell adhesion APP;CYP1B1 GO:0045087| innate immune response APP;PPARG GO:0010288| response to lead ion CAT;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;APP;PPARG GO:0007626| locomotory behavior APP;OPRM1;SOD1 GO:0002576| platelet degranulation SOD1;APP 19164:[DB14011 DB12610] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12610|Ebselen EPHX2 common genes common pathways GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;GPR12;HTR2A;EPHX2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;EPHX2;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0010628| positive regulation of gene expression EPHX2;TRPV4 GO:0019373| epoxygenase P450 pathway EPHX2;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0072593| reactive oxygen species metabolic process EPHX2;SOD1 GO:0008217| regulation of blood pressure SOD1;EPHX2;PTGS2;PTGS1;PPARG GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;EPHX2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP3A4;EPHX2;CYP3A7;CYP1A2;PTGS1 GO:0008152| metabolic process EPHX2;ACAT1;SMPD1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;EPHX2;NAAA;PTGS1;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0006954| inflammatory response ALOX5;PTGS1;EPHX2;CNR2;PTGS2;ALOX15;IDO1;TRPV1 19165:[DB14011 DB07063] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07063|{3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;AKR1B1;CYP1A1;CYP2C9;ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0022900| electron transport chain AKR1B1;IDO1;GSR;CYP1A2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;AKR1B1;CYP1A2;PTGS2;SOD1 19166:[DB14011 DB11397] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCHE;PPARG;CYP1B1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TF;TRPV3;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA1;TRPA1;CACNA1G GO:0001895| retina homeostasis ALB;TF;SOD1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;TF GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:0042493| response to drug CYP1A1;PPARG;TRPA1;BCHE;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0002576| platelet degranulation TF;SOD1;ALB GO:0007612| learning PTGS2;VDAC1;BCHE 19167:[DB14011 DB00600] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00600|Monobenzone TYR common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;TYR;ALOX5;PTGS1;GPX1 GO:0048538| thymus development SOD1;TYR GO:0051591| response to cAMP AANAT;TYR GO:0008152| metabolic process TYR;ACAT1;SMPD1 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1;TYR GO:0008283| cell proliferation TYR;GPX1;HTR1A;CYP1A1 GO:0033280| response to vitamin D PTGS2;TYR GO:0009411| response to UV CAT;TYR 19168:[DB14011 DB03889] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 19169:[DB14011 DB01831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways GO:0010628| positive regulation of gene expression WARS;TRPV4 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;WARS;PPARG GO:0001525| angiogenesis CYP1B1;WARS;PTGS2 19170:[DB14011 DB14527] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14527|Chromic nitrate CYB5A;TF common genes common pathways GO:0001895| retina homeostasis TF;SOD1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;GLRA3;TRPV3;TF;CACNA1H;CHRNA7;TRPV2 GO:0006879| cellular iron ion homeostasis TF;SOD1;ABCG2 GO:0046686| response to cadmium ion CAT;CYB5A GO:0002576| platelet degranulation SOD1;TF GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP3A7;CYB5A;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9 GO:0022900| electron transport chain IDO1;GSR;CYB5A;CYP1A2 19171:[DB14011 DB02637] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02637|Oxaloacetate Ion CS;mdh;SPR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;SPR;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1 GO:0006809| nitric oxide biosynthetic process SPR;CYP1B1 19172:[DB14011 DB08435] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes PPARG common pathways GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2 GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0015909| long-chain fatty acid transport PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0030224| monocyte differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation PPARG;ACAT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1 GO:0045087| innate immune response PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG GO:0030308| negative regulation of cell growth PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0006919| activation of caspase activity PPARG GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG GO:1905461| PPARG GO:1904706| PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0048469| cell maturation PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG 19173:[DB14011 DB07580] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07580|BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE APCS common genes common pathways GO:0061045| negative regulation of wound healing HMGCR;APCS GO:0002674| negative regulation of acute inflammatory response PPARG;APCS GO:0045087| innate immune response PPARG;APCS 19174:[DB14011 DB06410] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1A1;CYP2C9;CYP27A1;CRYZ GO:0006355| regulation of transcription, DNA-dependent VDR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;PPARG;PLA2G1B GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG GO:0010628| positive regulation of gene expression TRPV4;VDR GO:0046697| decidualization VDR;PTGS2 GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CHRNA7;VDR;TRPM8;TRPV4 GO:0007595| lactation SLC29A1;VDR GO:0006816| calcium ion transport TRPV2;VDR;CHRNA7;CACNA1H;TRPV3;CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR GO:0006351| transcription, DNA-dependent PPARG;VDR GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP27A1 GO:0008285| negative regulation of cell proliferation VDR;PTGS2;OPRM1;CYP1B1;PPARG GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;VDR;CHRNA7 19175:[DB14011 DB03948] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03948|6-Chloropurine Riboside, 5'-Monophosphate IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;IMPDH1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;IMPDH2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0043312| neutrophil degranulation IMPDH1;IMPDH2;ALOX5;CAT GO:0007623| circadian rhythm IMPDH2;AANAT GO:0051289| protein homotetramerization IMPDH2;CAT;CRYZ;TRPA1;TRPV1;TRPM8 19176:[DB14011 DB06721] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06721|Gimatecan SLCO1B1 common genes common pathways GO:0006811| ion transport TRPV3;CACNA1H;SLCO1B1;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1;SLCO1B1;TRPV3;CACNA1H;TRPV2 19177:[DB14011 DB04853] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04853|Binodenoson ADORA2A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;PPARG;ADORA2A;GPR18 GO:0006915| apoptotic process VDAC1;ADORA2A;GPX1 GO:0050714| positive regulation of protein secretion ADORA2A;PLA2G1B GO:0031000| response to caffeine PPARG;ADORA2A GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;ADORA2A;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0007626| locomotory behavior ADORA2A;OPRM1;SOD1 GO:0042311| vasodilation ADORA2A;GPX1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;PPARG GO:0042493| response to drug PPARG;CYP1A1;ADORA2A;TRPA1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0050728| negative regulation of inflammatory response ADORA2A;CNR2 GO:0001975| response to amphetamine ADORA2A;CNR2;SOD1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;ADORA2A;GPR18;PPARG GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1;SOD1 GO:0042755| eating behavior ADORA2A;OPRM1;OPRD1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;ADORA2A;PPARG GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;ADORA2A GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0007600| sensory perception ADORA2A;TRPV2;OPRM1 GO:0006954| inflammatory response ADORA2A;ALOX15;IDO1;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 19178:[DB14011 DB01947] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01947|RU78262 SRC common genes common pathways GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SRC;SOD1;PTGS2;HMGCR GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042493| response to drug SRC;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0016236| macroautophagy VDAC1;SRC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0002376| immune system process IDO1;SRC GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;SRC;ALOX15;TRPV4 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process SRC;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0042542| response to hydrogen peroxide SOD1;SRC;GPX1;CAT;TRPA1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;SRC;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption SRC;GPR55 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;SRC GO:0008283| cell proliferation CYP1A1;SRC;GPX1;HTR1A 19179:[DB14011 DB02515] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;PFKFB1 GO:0045821| positive regulation of glycolysis PFKFB1;HTR2A GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 GO:0032868| response to insulin stimulus CAT;AANAT;PFKFB1;TRPV4 GO:0042594| response to starvation PPARG;ACAT1;PFKFB1 GO:0031100| organ regeneration PFKFB1;PPARG GO:0051591| response to cAMP PFKFB1;AANAT 19180:[DB14011 DB04336] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04336|1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 19181:[DB14011 DB03486] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways GO:0007165| signal transduction CANT1;CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;CANT1 19182:[DB14011 DB07786] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07786|1-((1R,2S)-1-{2-[2-(4-CHLOROPHENYL)-1,3-BENZOXAZOL-7-YL]ETHYL}-2-HYDROXYPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE ADA common genes common pathways GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0001890| placenta development ADA;SOD1;PPARG GO:0042542| response to hydrogen peroxide ADA;GPX1;CAT;SOD1;TRPA1 GO:0001889| liver development CYP1A1;ADA;ACAT1 GO:0001666| response to hypoxia CYP1A1;ADA;CAT;CHRNA7 GO:0007568| aging ADA;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CYP1A1 GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0043278| response to morphine ADA;CNR1;OPRM1 GO:0042493| response to drug CAT;ADA;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;ADA;SOD1;PTGS2;HMGCR GO:0007155| cell adhesion ADA;CYP1B1 GO:0033197| response to vitamin E ADA;CAT GO:0030324| lung development ADA;CYP1A2 19183:[DB14011 DB07747] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07747|(3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 19184:[DB14011 DB14529] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14529|Chromium nicotinate CYB5A;TF common genes common pathways GO:0006879| cellular iron ion homeostasis TF;SOD1;ABCG2 GO:0001895| retina homeostasis SOD1;TF GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;TRPV3;TF;CACNA1H;GLRA3;TRPV2;CHRNA7 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYB5A;CYP3A7;SOD1;CYP3A4;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0022900| electron transport chain CYP1A2;CYB5A;IDO1;GSR GO:0002576| platelet degranulation SOD1;TF GO:0046686| response to cadmium ion CYB5A;CAT 19185:[DB14011 DB01678] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01678|RU84687 SRC common genes common pathways GO:0008283| cell proliferation CYP1A1;HTR1A;SRC;GPX1 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0045453| bone resorption SRC;GPR55 GO:0007165| signal transduction SRC;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;SRC;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0042542| response to hydrogen peroxide TRPA1;SRC;GPX1;CAT;SOD1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process SRC;IDO1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;SRC;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0016236| macroautophagy SRC;VDAC1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0009615| response to virus SRC;CYP1A1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;SRC;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC 19186:[DB14011 DB10772] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways GO:0043117| positive regulation of vascular permeability VEGFA;TGFB1;TRPV4 GO:0050796| regulation of insulin secretion TNF;IL1B;CNR1;IFNG GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;PDGFRA;HTR2A;OPRM1 GO:0051384| response to glucocorticoid stimulus IL6;TNF;PTGS2 GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0040014| regulation of multicellular organism growth SOD1;FGFR2 GO:0007566| embryo implantation IL1B;PTGS2;TGFBR2;SOD1 GO:0007165| signal transduction CHRNA7;FGF1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;IL1B;CACNA1I;PLA2G1B;EGFR;PPARG;GPR18;SMPD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;EGFR;IL6;PTGS2;VEGFA;OPRD1;TGFB1 GO:0007420| brain development ACAT1;TGFBR2 GO:0034116| positive regulation of heterotypic cell-cell adhesion IL1B;ALOX15;TNF GO:0065009| regulation of molecular function TRPV1;CSF2RA GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;EGFR GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0048662| negative regulation of smooth muscle cell proliferation IFNG;PPARG GO:0008283| cell proliferation TGFB1;FGF1;HTR1A;GPX1;CYP1A1;EGFR GO:0033280| response to vitamin D PTGS2;TGFB1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;EGFR;PTGS2;CYP1A2;TGFB1;TGFBR2;ACAT1;AANAT GO:0006919| activation of caspase activity TNF;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1;IL6 GO:0007584| response to nutrient PPARG;TGFBR2;CNR1;HMGCR GO:0032930| positive regulation of superoxide anion generation EGFR;TGFB1;SOD1 GO:0043627| response to estrogen stimulus PPARG;TGFBR2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;TGFB1 GO:0008285| negative regulation of cell proliferation TGFB1;PTGS2;OPRM1;TGFBR2;PPARG;IL6;CYP1B1;IL1B GO:0009791| post-embryonic development FGFR2;CYP1A2 GO:0071276| cellular response to cadmium ion EGFR;CYP1A2;SOD1 GO:0051781| positive regulation of cell division VEGFA;TGFB1;FGF1;FGFR2;CAT;IL1B GO:0045740| positive regulation of DNA replication PDGFRA;EGFR;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;PDGFRA;EGFR;TGFB1 GO:0031622| positive regulation of fever generation IL1B;TNF;CNR1;PTGS2 GO:0048469| cell maturation VEGFA;PPARG GO:0000060| protein import into nucleus, translocation IFNG;OPRD1;TGFB1;TNF GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;FGFR2;CAT GO:0007166| cell surface receptor linked signaling pathway TRPA1;EGFR;TRPV1;IFNG GO:0001525| angiogenesis FGFR2;PTGS2;VEGFA;FGF1;CYP1B1 GO:0001889| liver development CYP1A1;EGFR;ACAT1 GO:0051592| response to calcium ion EGFR;AANAT GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;EGFR;PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;TGFB1;CYP1B1;IL1B GO:0007399| nervous system development SMPD1;GLRB;VEGFA GO:0045165| cell fate commitment FGFR2;PPARG GO:0007507| heart development TGFB1;TGFBR2;PPARG GO:0001503| ossification ALOX15;EGFR GO:0071260| cellular response to mechanical stimulus IL1B;EGFR;TGFB1;PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;TGFB1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2;TGFB1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;IL6;PPARG;TNF;SMPD1;SOD1;CNR1;PTGS2;TGFB1 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0002666| positive regulation of T cell tolerance induction IDO1;TGFBR2 GO:0007565| female pregnancy IDO1;TGFB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;PTGS2 GO:0001934| positive regulation of protein phosphorylation FGF1;VEGFA;TGFB1;IFNG;CHRNA7;TNF;IL1B;EGFR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2;GPX1 GO:0010629| negative regulation of gene expression TNF;VEGFA;OPRD1;TGFB1;IFNG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;VEGFA;TGFB1;HTR2A GO:0007595| lactation VEGFA;SLC29A1 GO:0048565| digestive tract development CYP1A1;TGFB1;TGFBR2;FGFR2 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;IL1B GO:0030217| T cell differentiation TGFB1;GPR18 GO:0006954| inflammatory response CNR2;PTGS2;TGFB1;PTGS1;ALOX5;TNF;ALOX15;IL1B;IDO1;TRPV1;IL6 GO:0051092| positive regulation of NF-kappaB transcription factor activity TGFB1;CAT;TNF;PLA2G1B;IL6;IL1B GO:0006955| immune response IL6;IL1B;TNF;IFNG;OPRD1;CNR2 GO:0016032| viral reproduction HTR2A;PDGFRA;VDAC1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;IL1B;TNF;PPARG GO:0010468| regulation of gene expression TGFBR2;TGFB1;CYP1A2 GO:0071456| cellular response to hypoxia SLC29A1;VEGFA;PTGS2;OPRD1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PDGFRA;CAT GO:0030282| bone mineralization PTGS2;FGFR2;ALOX15 GO:0007568| aging PTGS2;HMGCR;TGFB1;NAPEPLD;TGFBR2;SOD1;HTR2A;CNR1;CAT;CYP1A1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TGFB1;TRPV1;EGFR GO:0009611| response to wounding CYP1A1;TGFB1;GPX1 GO:0032355| response to estradiol stimulus TGFB1;PTGS2;CYP1A2;CAT;EGFR GO:0032735| positive regulation of interleukin-12 production IDO1;IFNG GO:0002446| neutrophil mediated immunity IL6;PLA2G1B GO:0034605| cellular response to heat FGF1;PTGS2;TRPV4;TRPV1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0032966| negative regulation of collagen biosynthetic process PPARG;IL6 GO:0031100| organ regeneration TGFBR2;TGFB1;PPARG GO:0033993| response to lipid EGFR;PPARG GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;HTR2A;GPR12;TGFB1 GO:0045429| positive regulation of nitric oxide biosynthetic process IFNG;OPRM1;PTGS2;TRPV1;EGFR;IL1B;TNF GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;FGFR2;HTR2A;GPR55;HMGCR;TGFB1;OPRM1;VEGFA;ALOX15;EGFR;PDGFRA;TRPV4;TNF GO:0045766| positive regulation of angiogenesis VEGFA;FGF1;TGFBR2;CHRNA7;CYP1B1;IL1B GO:0060965| negative regulation of gene silencing by miRNA TGFB1;PPARG GO:0001541| ovarian follicle development VEGFA;SOD1 GO:0000187| activation of MAPK activity PLA2G1B;IL1B;TNF;CHRNA7;SOD1;FGF1 GO:0050714| positive regulation of protein secretion TGFB1;PLA2G1B GO:0030855| epithelial cell differentiation VEGFA;FGFR2;PPARG;VDAC1 GO:0006915| apoptotic process IL1B;VDAC1;TGFBR2;TGFB1;IFNG;FGFR2;GPX1 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;IL1B GO:0043406| positive regulation of MAP kinase activity EGFR;TNF;HTR2A;FGF1;TGFB1;VEGFA GO:0042130| negative regulation of T cell proliferation IDO1;TGFB1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF;TGFB1;IFNG GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;TNF;PTGS2;CYP1A2;TGFB1;TGFBR2;SOD1 GO:0001657| ureteric bud development TGFB1;FGFR2;CAT GO:0010628| positive regulation of gene expression IL1B;TRPV4;IL6;TNF;IFNG;VEGFA;TGFB1 GO:0007202| activation of phospholipase C activity EGFR;HTR2A;GPR55 GO:0001666| response to hypoxia CAT;CHRNA7;VEGFA;TGFB1;TGFBR2;CYP1A1 GO:0071230| cellular response to amino acid stimulus EGFR;TNF;GLRA1 GO:0030324| lung development FGFR2;CYP1A2;VEGFA;FGF1;TGFBR2;EGFR GO:0001660| fever generation IL1B;TRPV1 GO:0071639| positive regulation of monocyte chemotactic protein-1 production IL1B;TRPV4 GO:0046330| positive regulation of JNK cascade TNF;IL1B;TRPV4 GO:0032496| response to lipopolysaccharide FGFR2;CNR1;PTGS2;CNR2;OPRM1;CYP1A2;IL1B;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation EGFR;TNF;PTGS1;TGFBR2;PTGS2;TGFB1 GO:0042060| wound healing ALOX15;EGFR;PDGFRA;TGFBR2;TGFB1;OPRM1;FGFR2 GO:0007623| circadian rhythm EGFR;AANAT GO:0007611| learning or memory CHRNA7;CNR1;EGFR GO:0030308| negative regulation of cell growth TGFB1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;TNF;FGFR2;IFNG;VEGFA;TGFB1 GO:0035307| positive regulation of protein dephosphorylation SMPD1;TGFB1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2;TGFB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;PLA2G1B;IL6;EGFR;IL1B;VEGFA;TGFB1;FGF1;FGFR2 GO:0008284| positive regulation of cell proliferation FGFR2;IFNG;CHRNA7;HTR1A;FGF1;HTR2A;TGFBR2;VEGFA;PTGS2;TGFB1;HMGCR;IL1B;IL6;PDGFRA;EGFR GO:0009615| response to virus IFNG;CYP1A1;TNF GO:0002576| platelet degranulation SOD1;VEGFA;TGFB1 GO:0043066| negative regulation of apoptotic process IL6;EGFR;GPX1;CAT;PTGS2;VEGFA;HMGCR;SOD1 GO:0045786| negative regulation of cell cycle TGFB1;PTGS2 GO:0009612| response to mechanical stimulus TRPV4;PPARG;TGFBR2 GO:0035722| interleukin-12-mediated signaling pathway IFNG;SOD1 GO:0001822| kidney development CAT;VEGFA GO:0071300| cellular response to retinoic acid FGFR2;PPARG GO:0030224| monocyte differentiation PPARG;VEGFA GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;IL6 GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;IL6;TNF GO:0042493| response to drug PTGS2;CYP1A2;TGFB1;TGFBR2;HTR2A;SOD1;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent TGFB1;TNF;PPARG;EGFR;IL6;IL1B GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1;IL1B;TGFB1 GO:0061298| retina vasculature development in camera-type eye CYP1B1;PDGFRA GO:0060326| cell chemotaxis PDGFRA;ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGFR2;TGFB1;FGF1;EGFR;PDGFRA;TNF GO:0010742| macrophage derived foam cell differentiation TGFB1;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation TNF;IL6;EGFR;TGFBR2;HMGCR;PTGS2;FGFR2 19187:[DB14011 DB02107] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 19188:[DB14011 DB08488] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08488|4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 19189:[DB14011 DB07087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07087|4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0048511| rhythmic process PPARG;NCOA2;AANAT GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;PPARG;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;NCOA2;TRPV4;TRPV1;ESR1 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;ESR1;HTR1A;GPR55;CHRNA7 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV4;TRPV1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;PPARG 19190:[DB14011 DB04256] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;GRM1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GRM1;GPR18;GPR55 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0007216| metabotropic glutamate receptor signaling pathway DAGLA;GRM1 GO:0007626| locomotory behavior GRM1;SOD1;OPRM1 GO:0051930| regulation of sensory perception of pain GRM1;OPRM1;OPRD1 GO:0051966| regulation of synaptic transmission, glutamatergic GRM1;CNR1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;GRM1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GRM1;VDAC1;GLRB;GLRA1;CACNA1G GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;GRM1;TRPV1;TRPA1 19191:[DB14011 DB06538] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06538|Robalzotan HTR1A common genes HTR1A common pathways GO:0042310| vasoconstriction HTR1A GO:0042428| serotonin metabolic process HTR1A GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0007610| behavior HTR2A;HTR1A GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0001662| behavioral fear response VDAC1;HTR1A GO:0042053| regulation of dopamine metabolic process HTR1A GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1 GO:0050795| regulation of behavior HTR2A;HTR1A GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0035640| exploration behavior HTR1A GO:0007210| serotonin receptor signaling pathway HTR1A;HTR2A GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0014062| regulation of serotonin secretion HTR1A 19192:[DB14011 DB08156] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CA2;PTGS2;CYP1A2;SOD1 GO:0001822| kidney development CAT;CA2 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 19193:[DB14011 DB14002] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14002|D-alpha-Tocopherol acetate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes ALOX5;SOD1 common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG;SEC14L2 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0006355| regulation of transcription, DNA-dependent SEC14L2;PRKCB;PPP2CA;NR1I2;PPARG GO:0046685| response to arsenic-containing substance CYP1A1;GCLC GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;GSTO1;HMOX1;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;NQO1;CYP2C9;CYP1A1 GO:0007569| cell aging SOD1 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2;HMGCR GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0034465| response to carbon monoxide SOD1 GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0035094| response to nicotine CHRNA7;CNR1;HMOX1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2 GO:0030308| negative regulation of cell growth PPP2CA;PPARG GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0009410| response to xenobiotic stimulus GPX1;GCLC GO:0000302| response to reactive oxygen species GSTP1;CAT;GPX1;SOD1 GO:0071333| cellular response to glucose stimulus SLC29A1;GCLC GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;GSR;GSTP1 GO:0097332| SOD1 GO:0032259| methylation GSTO1;CYP1A2 GO:1902177| SOD1 GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;DGKA GO:0035722| interleukin-12-mediated signaling pathway GSTO1;GSTA2;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;GCLC;CAT;GPX1;NQO1;GSTP1 GO:0046677| response to antibiotic PPP2CB;CYP1A1;SOD1 GO:0002576| platelet degranulation SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NR1I2;PPARG GO:0007626| locomotory behavior OPRM1;SOD1 GO:0043312| neutrophil degranulation GSTP1;CAT;ALOX5 GO:0007155| cell adhesion PRKCA;CYP1B1 GO:0043200| response to amino acid stimulus GLRA3;GSTP1;GLRB GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0046686| response to cadmium ion CAT;GCLC GO:0006915| apoptotic process HMOX1;PRKCB;GPX1;PRKCA;PPP2CA;VDAC1 GO:0030855| epithelial cell differentiation GSTA2;PPARG;VDAC1 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0008219| cell death HMOX1;HTR2A GO:0001541| ovarian follicle development SOD1 GO:0045766| positive regulation of angiogenesis CYP1B1;PRKCA;HMOX1;PRKCB;CHRNA7 GO:0045540| regulation of cholesterol biosynthetic process SEC14L2;HMGCR GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;PRKCA;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;CHRNA7 GO:0001666| response to hypoxia CAT;CHRNA7;PRKCB;HMOX1;CYP1A1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1;TTPA GO:0046688| response to copper ion SOD1;AANAT GO:0007283| spermatogenesis SOD1;CNR1 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPP2CA;CYP1A1;PPARG;TRPA1 GO:2001300| ALOX5 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;GCLC GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0046716| muscle cell homeostasis SOD1 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;NR1I2;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1 GO:0034605| cellular response to heat HMOX1;PTGS2;TRPV1;TRPV4 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;GSTP1;NQO1 GO:0042554| superoxide anion generation SOD1 GO:0007568| aging NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT;GCLC;NQO1;CYP1A1 GO:0006810| transport TTPA;ABCC1;ABCG2;TRPV1;CACNA1I;TRPV2 GO:0071456| cellular response to hypoxia HMOX1;PTGS2;OPRD1;SLC29A1 GO:0010468| regulation of gene expression PPP2CB;CYP1A2 GO:0006979| response to oxidative stress PTGS2;HMOX1;SOD1;PTGS1;GPX1;CAT;GCLC;NQO1 GO:0098869| GSTP1;GSR;GPX1;PTGS1;CAT;PTGS2;GSTO1 GO:0006874| cellular calcium ion homeostasis PRKCB;CHRNA7;GPR12;HTR2A;TRPV4;TRPM8 GO:0051260| protein homooligomerization ACAT1;GLRA3;HMOX1;GLRA1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0002376| immune system process IDO1;PRKCB GO:0031100| organ regeneration GSTP1;PPARG GO:0048538| thymus development SOD1 GO:0007605| sensory perception of sound SOD1;GPX1 GO:0043085| positive regulation of catalytic activity SOD1 GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels GSTP1;SOD1 GO:0042738| exogenous drug catabolic process CYP2C19;NR1I2;CYP2C9;CYP3A4;CYP1A2 GO:0043524| negative regulation of neuron apoptosis HMOX1;SOD1;GCLC GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0019226| transmission of nerve impulse SOD1 GO:0006816| calcium ion transport TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1;TRPV2;PRKCB;CHRNA7;CACNA1H;TRPV3 GO:0043087| regulation of GTPase activity SOD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;PRKCB GO:0009408| response to heat TRPV1;SOD1;TRPV3;GCLC;TRPV2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;ALOX5;PTGS1;PTGS2;CNR2 GO:0006879| cellular iron ion homeostasis SOD1;HMOX1;ABCG2 GO:0009268| response to pH TTPA;TRPV1 GO:1904706| HMOX1;GSTP1;PPARG GO:0019430| removal of superoxide radicals NQO1;SOD1 GO:0008090| retrograde axon cargo transport SOD1 GO:0000303| response to superoxide SOD1 GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;SEC14L2;PRKCB GO:0001525| angiogenesis PTGS2;HMOX1;CYP1B1;PRKCA GO:0045471| response to ethanol CAT;SOD1;CNR1;OPRM1;HMGCR;GSTP1;NQO1 GO:0035556| intracellular signal transduction PLA2G1B;PRKCA;PRKCB;DGKA;HMOX1 GO:0008152| metabolic process GSTA2;GSTO1;DGKA;ACAT1;GSTM3;SMPD1;GSTP1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;GSTP1;CYP2C9;NQO1;NR1I2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;HMOX1;CNR1;SOD1;PTGS2 GO:0042542| response to hydrogen peroxide PPP2CB;TRPA1;GPX1;CAT;SOD1;HMOX1 GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;NAAA;PTGS1;GPX1;TTPA;PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0042953| lipoprotein transport PPARG;PRKCB GO:0071260| cellular response to mechanical stimulus GCLC;PTGS2 GO:0046620| regulation of organ growth SOD1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;NQO1;PPARG;CYP1A1 GO:0009636| response to toxin CYP1A1;NQO1;TTPA;GSTP1;CYP1B1;GPX1;CAT GO:0001895| retina homeostasis SOD1 GO:0006809| nitric oxide biosynthetic process NQO1;CYP1B1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0001890| placenta development SOD1;PPARG;TTPA GO:0042178| xenobiotic catabolic process GSTO1;CRYZ;GSTM3 GO:0034976| response to endoplasmic reticulum stress ALOX15;PPP2CB GO:0071276| cellular response to cadmium ion CYP1A2;HMOX1;SOD1 GO:0006749| glutathione metabolic process GSTO1;GSTA2;SOD1;GPX1;GCLC;GSTM3;GSTP1;GSR GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;HMOX1;CYP1B1;PPARG GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0014823| response to activity GCLC;CAT GO:0035865| cellular response to potassium ion SOD1;CACNA1H GO:0008217| regulation of blood pressure PTGS1;SOD1;HMOX1;PTGS2;PPARG GO:0043627| response to estrogen stimulus PPARG;GSTM3;HMOX1 GO:0032930| positive regulation of superoxide anion generation SOD1;GSTP1 GO:1902042| HMOX1;GPX1 GO:0007584| response to nutrient TTPA;NQO1;PPARG;GCLC;CNR1;HMGCR GO:0070301| cellular response to hydrogen peroxide CYP1B1;NQO1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0040014| regulation of multicellular organism growth SOD1 GO:0045454| cell redox homeostasis GSR;GCLC;GPX1 GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0002262| myeloid cell homeostasis SOD1 GO:0042908| xenobiotic transport ABCG2;NR1I2;ABCC1 GO:0032502| developmental process CYP1A1;TTPA GO:0050796| regulation of insulin secretion PRKCA;CNR1 GO:0032869| cellular response to insulin stimulus GCLC;PLA2G1B;GSTP1;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;HMOX1 GO:0001819| positive regulation of cytokine production SOD1 GO:0060047| heart contraction SOD1;GPX1 GO:0007165| signal transduction CHRNA7;PRKCB;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;NR1I2;GPR18;SMPD1 GO:0009725| response to hormone stimulus GCLC;ACAT1 19194:[DB14011 DB08190] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;NQO2;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0055114| oxidation-reduction process NQO2;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0022900| electron transport chain CYP1A2;NQO2;GSR;IDO1 19195:[DB14011 DB08221] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways GO:0043627| response to estrogen stimulus PPARG;TEK GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;TEK;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7 GO:0043434| response to peptide hormone stimulus TEK;TRPV1 GO:0001934| positive regulation of protein phosphorylation TEK;CHRNA7 GO:0035556| intracellular signal transduction TEK;PLA2G1B GO:0007507| heart development PPARG;TEK GO:0001525| angiogenesis PTGS2;TEK;CYP1B1 GO:0001666| response to hypoxia CYP1A1;TEK;CHRNA7;CAT GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1;TEK GO:0051591| response to cAMP AANAT;TEK GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;TEK;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0045766| positive regulation of angiogenesis CHRNA7;TEK;CYP1B1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;TEK GO:0050728| negative regulation of inflammatory response CNR2;TEK GO:0016525| negative regulation of angiogenesis TEK;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TEK GO:0043066| negative regulation of apoptotic process TEK;PTGS2;HMGCR;SOD1;GPX1;CAT 19196:[DB14011 DB06868] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06868|N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide F2 common genes common pathways GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 19197:[DB14011 DB04578] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;DPP4 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DPP4 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell HTR2A;DPP4 19198:[DB14011 DB01349] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes CYP3A4 common pathways GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TRPV1;ALOX15;AGTR2;IDO1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0050727| regulation of inflammatory response AGTR1;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0035556| intracellular signal transduction AGTR2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPA1;AGTR2;TRPV1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0043537| negative regulation of blood vessel endothelial cell migration AGTR2;PPARG GO:0008217| regulation of blood pressure PPARG;AGTR2;PTGS2;SOD1;PTGS1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;AGTR2;CACNA1I;PLA2G1B;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;AGTR1 GO:0007420| brain development AGTR2;ACAT1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0050729| positive regulation of inflammatory response TRPV4;AGTR1 GO:0035640| exploration behavior AGTR2;HTR1A GO:0060326| cell chemotaxis ABCC1;AGTR1 GO:0010243| response to organic nitrogen PTGS2;AGTR2;TRPV1 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AGTR2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;AGTR2 GO:0042311| vasodilation GPX1;AGTR2 GO:0001822| kidney development AGTR2;AGTR1;CAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;AGTR1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0042127| regulation of cell proliferation AGTR1;PTGS1;PTGS2 GO:0030308| negative regulation of cell growth AGTR2;PPARG GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger AGTR1;GPR55;GPR18 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;AGTR2;OPRM1;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;AGTR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;AGTR1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;HMGCR;CYP3A7;CYP1A2;CYP3A4 19199:[DB14011 DB11774] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11774|Pazufloxacin CYP1A2 common genes CYP1A2 common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;CYP1A1;IDO1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 19200:[DB14011 DB04910] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04910|Oxibendazole TUBB4B common genes common pathways GO:0043312| neutrophil degranulation TUBB4B;ALOX5;CAT 19201:[DB14011 DB08772] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP1A1;CYP2C9;AKR1B1;CRYZ;AKR1B10 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0022900| electron transport chain IDO1;GSR;AKR1B1;CYP1A2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG;AKR1B1 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;AKR1B10;CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19 GO:0001523| retinoid metabolic process NAPEPLD;AKR1B10 19202:[DB14011 DB08222] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PNLIP;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;CLPS;CYP2C9;PPARG GO:0001523| retinoid metabolic process CLPS;PNLIP;NAPEPLD GO:0032094| response to food OPRM1;CYP1A1;CLPS GO:0043085| positive regulation of catalytic activity SOD1;CLPS GO:0016042| lipid catabolic process NAPEPLD;PNLIP;CLPS;PLA2G1B;DAGLA 19203:[DB14011 DB02131] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02131|N-1-Methylheptylformamide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;ADH1C;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 19204:[DB14011 DB01951] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01951|Gpi-1046 FKBP1A common genes common pathways GO:0006936| muscle contraction FKBP1A;GLRA1;CACNA1H GO:0051209| release of sequestered calcium ion into cytosol HTR2A;FKBP1A;TRPV1;TRPA1 GO:1902991| CHRNA7;FKBP1A GO:0031000| response to caffeine FKBP1A;PPARG GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;FKBP1A;CACNA1I;TRPV4;TRPV1;TRPV3;OPRM1;CACNA1H;CHRNA7;TRPV2 19205:[DB14011 DB09154] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways GO:0055085| transmembrane transport TRPA1;ABCC1;SLC13A2;CACNA1G;SLC25A21;TRPM8;ABCG2;SLC13A5;TRPV1;VDAC1;CACNA1I;TRPV4;TRPV3;CACNA1H;SLC25A1;TRPV2 GO:0006810| transport TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1;SLC13A2 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;VDAC1;TRPV4;GLRB;CACNA1I;SLC13A5;TRPV1;TRPM8;CACNA1G;SLC13A2;GLRA1;TRPA1 GO:0098656| VDAC1;SLC13A2 19206:[DB14011 DB00140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;BLVRB;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;MAOA;MTHFR;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;MTHFR;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0051260| protein homooligomerization SLC22A6;GLRA1;ACAT1;GLRA3 GO:0001666| response to hypoxia MTHFR;CHRNA7;CAT;CYP1A1 GO:0006915| apoptotic process RFK;VDAC1;GPX1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G;SLC22A6 GO:0043200| response to amino acid stimulus MTHFR;GLRA3;GLRB GO:0008152| metabolic process SMPD1;ACAT1;MTHFR GO:0072593| reactive oxygen species metabolic process SOD1;RFK GO:0098656| VDAC1;SLC22A6 19207:[DB14011 DB00710] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00710|Ibandronate FDPS common genes common pathways GO:0016032| viral reproduction VDAC1;FDPS;HTR2A GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;NAAA;GPX1;PTGS1;FDPS;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0045540| regulation of cholesterol biosynthetic process HMGCR;FDPS GO:0008299| isoprenoid biosynthetic process FDPS;HMGCR GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;FDPS;CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0006694| steroid biosynthetic process CYP17A1;FDPS;HMGCR GO:0006695| cholesterol biosynthetic process HMGCR;FDPS GO:0008203| cholesterol metabolic process HMGCR;CAT;FDPS 19208:[DB14011 DB00144] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0033344| cholesterol efflux ABCG2;SCARB1 GO:0042060| wound healing ALOX15;SCARB1;OPRM1 GO:0007612| learning VDAC1;PTGS2;ATP8A1 GO:0043312| neutrophil degranulation CAT;ATP8A1;ALOX5 GO:0007155| cell adhesion CYP1B1;PRKCA GO:0006685| sphingomyelin catabolic process SMPD3;SMPD4;SMPD1 GO:0006687| glycosphingolipid metabolic process SMPD4;SMPD3;SMPD1 GO:0051260| protein homooligomerization GLRA1;DGKD;ACAT1;GLRA3 GO:0006915| apoptotic process GPX1;VDAC1;PRKCA GO:0045766| positive regulation of angiogenesis CYP1B1;PRKCA;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade PRKCA;ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;CHRNA7;ATP8A1;GLRA3 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;DGKD;SOD1;PTGS2;CYP1A2 GO:0071356| cellular response to tumor necrosis factor TRPV1;SMPD4 GO:0001525| angiogenesis PTGS2;CYP1B1;PRKCA GO:0046513| ceramide biosynthetic process SMPD4;SMPD1 GO:0006684| sphingomyelin metabolic process SMPD1;SMPD3 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;SMPD3;HMGCR;PTDSS2;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;PISD;TRPV1;PLA2G1B;PPARG;CYP2C9;PTDSS1 GO:0035556| intracellular signal transduction DGKG;DGKD;PRKCA;PLA2G1B GO:0008152| metabolic process DGKD;SMPD1;DGKG;ACAT1 GO:0043534| blood vessel endothelial cell migration SCARB1;GPX1 GO:0016032| viral reproduction HTR2A;SCARB1;VDAC1 GO:0050796| regulation of insulin secretion PRKCA;CNR1 GO:0045332| phospholipid translocation ABCC1;ATP8A1 GO:0046718| entry of virus into host cell HTR2A;SCARB1 GO:0007165| signal transduction DGKD;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;DGKG;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 GO:0006702| androgen biosynthetic process SCARB1;CYP17A1 19209:[DB14011 DB06954] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06954|2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate CA2 common genes common pathways GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CA2;TRPA1;PPARG;CYP1A1 GO:0001822| kidney development CAT;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 19210:[DB14011 DB00511] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;ATP1A1;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0008217| regulation of blood pressure PPARG;PTGS1;ATP1A1;SOD1;PTGS2 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;ATP1A1;GLRB;TRPV1;GLRA1;TRPA1 GO:0086002| CACNA1G;ATP1A1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;ATP1A1;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 19211:[DB14011 DB00917] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;PTGDR2;GLRA3;HTR2A;OPRM1;OPRD1 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0006955| immune response PTGDR2;OPRD1;CNR2;PTGER4 GO:0031622| positive regulation of fever generation PTGER3;PTGS2;CNR1 GO:0016125| sterol metabolic process CYP11A1;CYP19A1;CYP17A1;CYP1B1 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger PTGER4;CNR1 GO:0071260| cellular response to mechanical stimulus PTGS2;PTGER4 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP11A1;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;ABCC4;AANAT;ACAT1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC22A8 GO:0006811| ion transport SLCO4A1;SLC22A7;CHRNA7;SLC22A11;TRPV2;SLCO1B1;GLRA3;SLC22A8;CACNA1H;SLCO3A1;TRPV3;SLCO1A2;SLCO2B1;TRPM8;SLC22A2;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPA1;GLRA1;CACNA1G;SLCO1C1 GO:0006855| drug transmembrane transport ABCG2;SLC22A2;ABCC1 GO:0071380| cellular response to prostaglandin E stimulus PTGER4;PPARG;PTGER2 GO:0098656| SLC22A6;VDAC1;SLC22A8;SLC22A7 GO:0006812| cation transport SLC22A2;TRPM8 GO:0050729| positive regulation of inflammatory response TRPV4;PTGER4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway PTGDR2;OPRM1;OPRD1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;PTGER4;PTGDR2;CHRNA7;PTGER2;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;PTGER3;OPRM1;PTGER1;CNR2 GO:0099133| ABCC5;ABCC1;ABCC4 GO:0022900| electron transport chain GSR;IDO1;CYP19A1;CYP1A2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCC4;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP19A1;CYP2C9;CYP1A1;CRYZ;CAT;GPX1;ALOX5;PTGS1;ABCC4;CYP3A4;CYP11A1;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:0006694| steroid biosynthetic process CYP11A1;HMGCR;CYP19A1;CYP17A1 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;HMGCR;PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2;ABCC4 GO:0050728| negative regulation of inflammatory response CNR2;PTGER4 GO:0032496| response to lipopolysaccharide CYP1A1;PTGER4;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2;PTGER1;PTGER2 GO:0008203| cholesterol metabolic process CAT;CYP11A1;HMGCR GO:0042127| regulation of cell proliferation PTGS1;PTGER2;PTGS2 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;PTGER3;OPRD1;OPRM1 GO:0009612| response to mechanical stimulus PTGER4;PPARG;TRPV4 GO:0007218| neuropeptide signaling pathway PTGDR2;OPRM1;OPRD1;GLRA3;GLRB;GLRA1 GO:0002576| platelet degranulation ABCC4;SOD1 GO:0008219| cell death PTGER3;HTR2A GO:0055085| transmembrane transport TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;SLCO2B1;ABCC5;SLC22A2;SLC51B;ABCG2;SLCO1C1;SLCO2A1;ABCC1;SLC22A6;CACNA1G;SLC51A;TRPA1;ABCC4;TRPV2;SLC22A11;SLCO4A1;SLC22A7;SLCO3A1;SLCO1A2;TRPV3;CACNA1H;SLCO1B1;SLC22A8 GO:0042359| vitamin D metabolic process CYP11A1;CYP3A4;CYP1A1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;ABCC4;SOD1;CYP1A2;PTGS2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGDR2;CNR1;OPRD1;CNR2;OPRM1 GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP11A1 GO:0007186| G-protein coupled receptor signaling pathway PTGER2;PTGDR2;OPRM1;CNR2;PTGER1;PTGER3;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PTGER4;PPARG;GPR18 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;ABCC5;TRPV2 GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 19212:[DB14011 DB03963] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03963|S-(Dimethylarsenic)Cysteine TLR2;NOS3;COPG1;XRCC4;msrA common genes common pathways GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;NOS3;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;TLR2;ALOX15 GO:0050830| defense response to Gram-positive bacterium TLR2;PLA2G1B GO:0043312| neutrophil degranulation CAT;ALOX5;TLR2 GO:0045087| innate immune response PPARG;TLR2 GO:0042311| vasodilation GPX1;NOS3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TLR2 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0030324| lung development CYP1A2;NOS3 GO:0032496| response to lipopolysaccharide TLR2;CYP1A1;IDO1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0007612| learning VDAC1;TLR2;PTGS2 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;TLR2 GO:0001666| response to hypoxia TLR2;CYP1A1;CAT;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;TLR2 GO:0045766| positive regulation of angiogenesis CYP1B1;NOS3;CHRNA7 GO:0006915| apoptotic process GPX1;TLR2;VDAC1 GO:0002376| immune system process IDO1;TLR2 GO:0032735| positive regulation of interleukin-12 production IDO1;TLR2 GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0006955| immune response OPRD1;CNR2;TLR2 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;IDO1;ALOX15;TRPV1;TLR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;TLR2 GO:0009408| response to heat NOS3;TRPV1;SOD1;TRPV3;TRPV2 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure NOS3;CNR1 GO:0001774| microglial cell activation TRPV1;TLR2 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;TLR2;CYP1B1;NOS3 GO:1902042| NOS3;GPX1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4;TLR2 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0009636| response to toxin CAT;GPX1;CYP1B1;CYP1A1;TLR2 GO:0070542| response to fatty acid TLR2;CAT;PTGS2 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;TLR2;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0045454| cell redox homeostasis NOS3;GSR;GPX1 GO:0050729| positive regulation of inflammatory response TRPV4;TLR2 19213:[DB14011 DB00331] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0051260| protein homooligomerization SLC22A1;GLRA1;ACAT1;GLRA3 GO:1901642| SLC29A4;SLC29A1 GO:0010628| positive regulation of gene expression PRKAB1;TRPV4 GO:0055085| transmembrane transport CACNA1H;SLC22A3;TRPV3;SLC29A4;SLC47A1;TRPV2;SLC47A2;CACNA1G;ABCC1;SLC22A1;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;SLC22A2;TRPM8 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PRKAB1;PTGS2 GO:0016236| macroautophagy VDAC1;PRKAB1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;PRKAB1;CHRNA7 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PRKAB1;PTGS2 GO:0051291| protein heterooligomerization GLRB;GLRA1;PRKAB1 GO:0006812| cation transport SLC22A2;TRPM8;SLC22A1 GO:0006811| ion transport GLRA3;TRPV3;SLC22A3;CACNA1H;CHRNA7;TRPV2;TRPA1;GLRA1;SLC22A1;CACNA1G;SLC22A2;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1 GO:0006855| drug transmembrane transport SLC22A3;SLC47A2;SLC47A1;SLC22A1;ABCC1;SLC22A2;ABCG2 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;PRKAB1 19214:[DB14011 DB08353] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08353|2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0048511| rhythmic process PPARG;CSNK2A1;AANAT GO:0006915| apoptotic process GPX1;CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0008284| positive regulation of cell proliferation CHRNA7;CSNK2A1;HMGCR;PTGS2;HTR2A;HTR1A GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CSNK2A1;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CSNK2A1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 19215:[DB14011 DB03292] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways GO:0009612| response to mechanical stimulus PPARG;PSPH;TRPV4 GO:0031667| response to nutrient levels PSPH;SOD1 19216:[DB14011 DB07700] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0019371| cyclooxygenase pathway PTGS2;AKR1C3;PTGS1 GO:0071379| cellular response to prostaglandin stimulus AKR1C3;PPARG GO:0010942| positive regulation of cell death AKR1C3;PTGS2 GO:0042448| progesterone metabolic process AKR1C3;CYP17A1 GO:0000060| protein import into nucleus, translocation AKR1C3;OPRD1 GO:0071277| cellular response to calcium ion ALOX15;AKR1C3 GO:0006693| prostaglandin metabolic process AKR1C3;PTGS2;PTGS1 GO:0042572| retinol metabolic process CYP1B1;AKR1C3 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;AKR1C3 GO:0001523| retinoid metabolic process AKR1C3;NAPEPLD GO:0007584| response to nutrient PPARG;CNR1;AKR1C3;HMGCR GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;AKR1C3;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;AKR1C3 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;AKR1C3;HTR1A;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;AKR1C3;HTR1A;GPR55;CNR1;GPR12;HTR2A;PPARG;GPR18 GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP3A4;CYP1A2;CYP3A7;HMGCR;AKR1C3 GO:0042574| retinal metabolic process AKR1C3;CYP1B1 19217:[DB14011 DB01271] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01271|Idursulfase PLIN3 common genes common pathways 19218:[DB14011 DB09342] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09342|Propoxycaine CES1 common genes common pathways GO:0030855| epithelial cell differentiation CES1;VDAC1;PPARG GO:0006695| cholesterol biosynthetic process CES1;HMGCR GO:0009636| response to toxin CAT;GPX1;CES1;CYP1B1;CYP1A1 GO:0008152| metabolic process SMPD1;ACAT1;CES1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CES1;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 19219:[DB14011 DB07680] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07680|[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID CMA1 common genes common pathways GO:0045766| positive regulation of angiogenesis CMA1;CHRNA7;CYP1B1 GO:0071333| cellular response to glucose stimulus SLC29A1;CMA1 GO:0050727| regulation of inflammatory response CMA1;PTGS2 19220:[DB14011 DB04951] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04951|Pirfenidone FURIN;CYP1A2 common genes CYP1A2 common pathways GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;CYP1A2;PTGS2 GO:0045333| cellular respiration CYP1A2 GO:0008283| cell proliferation CYP1A1;FURIN;HTR1A;GPX1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 19221:[DB14011 DB04957] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes CYP3A5;CYP3A4;CYP1A1 common pathways GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0009308| amine metabolic process CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0032094| response to food OPRM1;CYP1A1 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0046685| response to arsenic-containing substance CYP1A1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0009615| response to virus CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0009812| flavonoid metabolic process CYP1A1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0036378| CYP3A4 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;KCNQ1;CACNA1I;TRPV4;VDAC1;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;KCNH2;TRPV3 GO:0086002| CACNA1G;KCNE1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0002933| CYP3A7;CYP3A4;CYP3A5;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0007605| sensory perception of sound KCNQ1;GPX1;KCNE1;SOD1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0042391| regulation of membrane potential GLRA1;CACNA1G;GLRB;KCNH2;CACNA1H GO:0010041| response to iron(III) ion CYP1A1 GO:0007568| aging CAT;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0009611| response to wounding CYP1A1;GPX1 GO:0086010| KCNH2;CACNA1H;CACNA1G;CACNA1I GO:0048565| digestive tract development CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0008209| androgen metabolic process CYP3A4 GO:0009635| response to herbicide CYP1A1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0071320| cellular response to cAMP AANAT;KCNE1;KCNQ1 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0070988| demethylation CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0008016| regulation of heart contraction CACNA1H;KCNQ1 GO:0086091| KCNE1;KCNH2;CACNA1G;KCNQ1 GO:0009692| ethylene metabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP1A2 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 GO:0009624| response to nematode CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;KCNQ1;GLRA3;KCNH2;CACNA1H;KCNE1;TRPV3;CHRNA7;TRPV2 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0043010| camera-type eye development CYP1A1 GO:0034765| regulation of ion transmembrane transport KCNH2;CACNA1H;KCNE1;CACNA1G;CACNA1I;KCNQ1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0032502| developmental process CYP1A1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:1900087| CYP1A1 19222:[DB14011 DB04919] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04919|Alfimeprase FGA;FGB common genes common pathways GO:0002376| immune system process FGA;IDO1;FGB GO:0050714| positive regulation of protein secretion FGB;FGA;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade FGB;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55;FGA;TRPV4;ALOX15 GO:0045087| innate immune response FGB;PPARG;FGA GO:0002576| platelet degranulation FGA;SOD1;FGB GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;FGA;FGB GO:0007165| signal transduction FGA;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;FGB;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0045907| positive regulation of vasoconstriction FGA;FGB;PTGS2;HTR2A GO:1902042| FGA;FGB;GPX1 GO:0051592| response to calcium ion FGB;AANAT;FGA 19223:[DB14011 DB05679] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways GO:0002862| negative regulation of inflammatory response to antigenic stimulus GPX1;IL12B GO:0035722| interleukin-12-mediated signaling pathway IL12B;SOD1;IL23A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;IL23A GO:0045087| innate immune response IL23A;PPARG GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;IL12B;SOD1;CYP1A2;PTGS2 GO:0002376| immune system process IDO1;IL23A GO:0032735| positive regulation of interleukin-12 production IL23A;IDO1;IL12B GO:0006955| immune response IL23A;OPRD1;CNR2 GO:0006954| inflammatory response IL23A;PTGS1;ALOX5;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0032693| negative regulation of interleukin-10 production IL23A;IDO1;IL12B GO:0019233| sensory perception of pain OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1;IL12B;TRPV1;TRPA1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;IL12B;TRPA1 GO:0008283| cell proliferation IL12B;CYP1A1;GPX1;HTR1A GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IL12B GO:0050729| positive regulation of inflammatory response TRPV4;IL12B;IL23A 19224:[DB14011 DB07017] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07017|(5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;HSD11B1;NAAA;GPX1;PTGS1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1;HSD11B1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0006704| glucocorticoid biosynthetic process HSD11B1;CYP17A1 GO:0030324| lung development HSD11B1;CYP1A2 GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;HSD11B1;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR 19225:[DB14011 DB13203] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13203|Bamifylline CYP1A2 common genes CYP1A2 common pathways GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;CYP1A1;IDO1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;PTGS1;GPX1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 19226:[DB14011 DB06479] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06479|Propentofylline PDE4A;CYP1A2 common genes CYP1A2 common pathways GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;PDE4A;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7 GO:0097267| CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;PDE4A;OPRD1 GO:0010468| regulation of gene expression CYP1A2 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 19227:[DB14011 DB08885] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways GO:0051781| positive regulation of cell division VEGFA;PGF;VEGFB;CAT GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA;OPRD1 GO:0007165| signal transduction GPR12;CNR1;HTR2A;PGF;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0032870| cellular response to hormone stimulus PGF;CACNA1H GO:0043117| positive regulation of vascular permeability TRPV4;VEGFB;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A;VEGFB GO:0007595| lactation SLC29A1;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;VEGFA;PTGS2 GO:0007565| female pregnancy PGF;IDO1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0010629| negative regulation of gene expression VEGFB;VEGFA;OPRD1 GO:0043524| negative regulation of neuron apoptosis SOD1;VEGFB GO:0007507| heart development PPARG;VEGFB GO:0007399| nervous system development SMPD1;GLRB;VEGFA GO:0048469| cell maturation VEGFA;PPARG GO:0001525| angiogenesis VEGFB;PGF;PTGS2;VEGFA;CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0043406| positive regulation of MAP kinase activity VEGFA;HTR2A GO:0010628| positive regulation of gene expression VEGFA;TRPV4 GO:0001666| response to hypoxia CAT;CHRNA7;VEGFB;PGF;VEGFA;CYP1A1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;VEGFB;GPR55;HTR2A;OPRM1;VEGFA;HMGCR;ALOX15;TRPV4 GO:0030855| epithelial cell differentiation VDAC1;PPARG;VEGFA GO:0045766| positive regulation of angiogenesis CHRNA7;VEGFB;PGF;VEGFA;CYP1B1 GO:0001541| ovarian follicle development VEGFA;SOD1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0031100| organ regeneration PGF;PPARG GO:0071456| cellular response to hypoxia PTGS2;VEGFA;OPRD1;SLC29A1 GO:0051897| positive regulation of protein kinase B signaling cascade VEGFB;GPX1 GO:0030224| monocyte differentiation VEGFA;PPARG GO:0042493| response to drug HTR2A;SOD1;PGF;PTGS2;CYP1A2;CAT;VEGFB;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;TRPV1;TRPV4 GO:0002576| platelet degranulation SOD1;VEGFA;VEGFB GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;PGF;HTR2A;VEGFA;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;PLA2G1B GO:0001822| kidney development VEGFA;CAT GO:0043066| negative regulation of apoptotic process CAT;GPX1;VEGFB;SOD1;PTGS2;VEGFA;HMGCR GO:0030324| lung development CYP1A2;VEGFA 19228:[DB14011 DB03832] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways GO:0006631| fatty acid metabolic process ALOX15;PTGS2;CROT;PTGS1 GO:0006635| fatty acid beta-oxidation CROT;ACAT1 GO:0015936| coenzyme A metabolic process CROT;ACAT1;HMGCR GO:0006629| lipid metabolic process CROT;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG 19229:[DB14011 DB02353] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways GO:0010759| positive regulation of macrophage chemotaxis CCL5;TRPV4 GO:0006955| immune response CNR2;CCL5;OPRD1 GO:0006816| calcium ion transport CHRNA7;TRPV2;TRPV3;CACNA1H;CCL5;TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G GO:0006954| inflammatory response CNR2;PTGS2;CCL5;ALOX5;PTGS1;ALOX15;IDO1;TRPV1 GO:0050796| regulation of insulin secretion CNR1;CCL5 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;CCL5 GO:0070233| negative regulation of T cell apoptosis CCL5;IDO1 GO:0009615| response to virus CYP1A1;CCL5 GO:0034097| response to cytokine stimulus AANAT;CCL5;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;CCL5;PTGS2 GO:0070234| positive regulation of T cell apoptosis IDO1;CCL5 GO:0071407| cellular response to organic cyclic compound CCL5;CYP1B1;CYP1A1 GO:0030593| neutrophil chemotaxis PLA2G1B;CCL5 GO:0046427| positive regulation of JAK-STAT cascade CCL5;CYP1B1 GO:1901214| CCL5;CHRNA7 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CCL5;CHRNA7;TRPM8;TRPV4 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CCL5;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;GPR18;PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CCL5;CAT GO:0051262| protein tetramerization HMGCR;CCL5;CAT GO:0071356| cellular response to tumor necrosis factor CCL5;TRPV1 GO:0034612| response to tumor necrosis factor CCL5;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;HMGCR;CCL5;OPRM1;HTR2A;GPR55 19230:[DB14011 DB08750] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CYP1A1;NOS2;IDO1 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;NOS2;CRYZ GO:0045454| cell redox homeostasis GPX1;GSR;NOS2 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 19231:[DB14011 DB02691] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;FABP6;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0006811| ion transport TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;SLCO1B3;SLCO1B1;GLRA3;CACNA1H;TRPV3;SLCO1A2 GO:0008285| negative regulation of cell proliferation FABP6;PPARG;CYP1B1;PTGS2;OPRM1 GO:0055085| transmembrane transport TRPV2;TRPV3;SLCO1A2;CACNA1H;SLCO1B1;SLCO1B3;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 19232:[DB14011 DB01889] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01889|16,17-Androstene-3-Ol NR1I3 common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;GPR12;CNR1;HTR2A;GPR55;HTR1A;NR1I3;OPRD1;OPRM1;CNR2;CHRNA7 GO:0043401| steroid hormone mediated signaling pathway NR1I3;PPARG GO:0006351| transcription, DNA-dependent PPARG;NR1I3 GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I3 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I3;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;PPARG;PLA2G1B 19233:[DB14011 DB01733] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01733|L-Phospholactate PKM common genes common pathways GO:0043312| neutrophil degranulation CAT;PKM;ALOX5 GO:0031100| organ regeneration PKM;PPARG GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PKM;CYP1A1;PPARG;TRPA1 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;PKM GO:0008152| metabolic process PKM;ACAT1;SMPD1 GO:0001889| liver development ACAT1;PKM;CYP1A1 GO:0043403| skeletal muscle tissue regeneration PKM;GPX1 GO:0051289| protein homotetramerization PKM;CAT;TRPV1;TRPM8;TRPA1;CRYZ GO:0032869| cellular response to insulin stimulus PKM;PLA2G1B;PPARG GO:0007584| response to nutrient PPARG;PKM;HMGCR;CNR1 GO:0032868| response to insulin stimulus CAT;AANAT;PKM;TRPV4 19234:[DB14011 DB01399] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01399|Salsalate PTGS2;PTGS1 common genes PTGS1;PTGS2 common pathways GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPV1;TRPA1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:1990776| PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0007568| aging NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CAT;CYP1A1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR 19235:[DB14011 DB05514] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05514|Cobiprostone CLCN2 common genes common pathways GO:0006810| transport TRPV2;CLCN2;TRPV1;CACNA1I;ABCG2;ABCC1 GO:0055085| transmembrane transport CACNA1I;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H;CLCN2 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;CLCN2;GLRA3;CHRNA7 GO:1902476| GLRA1;GLRB;GLRA3;CLCN2 GO:0006821| chloride transport GLRB;GLRA1;CLCN2;GLRA3 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;CLCN2 GO:0006811| ion transport CLCN2;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1 19236:[DB14011 DB07831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;ABL1;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;HTR2A GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;ABL1 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0007155| cell adhesion CYP1B1;ABL1 GO:0045087| innate immune response ABL1;PPARG GO:0042127| regulation of cell proliferation ABL1;PTGS1;PTGS2 GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;GSR;ABL1 GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0048538| thymus development ABL1;SOD1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;ABL1;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0006915| apoptotic process GPX1;ABL1;VDAC1 19237:[DB14011 DB07093] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07093|{3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;AKR1B1;CYP1A1;CYP2C9 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0022900| electron transport chain IDO1;GSR;AKR1B1;CYP1A2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 19238:[DB14011 DB01272] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01272|Alglucosidase alfa M6PR common genes common pathways GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;M6PR;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 19239:[DB14011 DB09091] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0010977| negative regulation of neuron projection development HDAC2;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent HDAC2;PPARG GO:0031000| response to caffeine HDAC2;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;PPARG GO:0048511| rhythmic process PPARG;HDAC2;AANAT GO:0042220| response to cocaine SMPD1;CNR1;OPRM1;HDAC2 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2;HDAC2 GO:0055093| response to hyperoxia CYP1A1;HDAC2;CAT GO:0035094| response to nicotine HDAC2;CHRNA7;CNR1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;HDAC2;NR3C1 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;HDAC2;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HDAC2;PTGS2;HMGCR;SOD1 GO:0071300| cellular response to retinoic acid HDAC2;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HDAC2;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;HDAC2;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;HDAC2;NR3C1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;HDAC2;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0070301| cellular response to hydrogen peroxide CYP1B1;HDAC2 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;NR3C1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0001975| response to amphetamine HDAC2;SOD1;CNR2 GO:0048149| behavioral response to ethanol HDAC2;OPRM1 GO:0006351| transcription, DNA-dependent PPARG;HDAC2;NR3C1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG 19240:[DB14011 DB07527] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07527|N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE F2 common genes common pathways GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0061844| F2;PLA2G1B 19241:[DB14011 DB04394] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04394|3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide CA2 common genes common pathways GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1;CA2 GO:0001822| kidney development CAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 19242:[DB14011 DB07446] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07446|N-(biphenyl-4-ylsulfonyl)-D-leucine MMP12 common genes common pathways GO:0042060| wound healing OPRM1;MMP12;ALOX15 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;PPARG;TRPV4;TRPV1 GO:0010628| positive regulation of gene expression TRPV4;MMP12 19243:[DB14011 DB04601] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04601|4-[(4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE CA2 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CA2;CYP1A1;PPARG;TRPA1 GO:0001822| kidney development CAT;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 19244:[DB14011 DB07396] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways GO:0008152| metabolic process PYGL;SMPD1;ACAT1 GO:0043312| neutrophil degranulation PYGL;ALOX5;CAT GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;PYGL 19245:[DB14011 DB05796] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05796|Daglutril MME common genes common pathways GO:0071345| cellular response to cytokine stimulus MME;TRPV1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRM1;MME;CNR2;PTGS2;OPRD1;HTR2A;CNR1 GO:0043312| neutrophil degranulation MME;ALOX5;CAT GO:0001822| kidney development MME;CAT 19246:[DB14011 DB00078] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0043312| neutrophil degranulation FCGR2A;FCGR3B;CAT;ALOX5 GO:0045087| innate immune response PPARG;C1R;C1QB;FCGR1A;C1S;C1QC;C1QA GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0002376| immune system process C1QC;C1S;C1QA;C1QB;C1R;FCGR2A;FCGR1A;IDO1 GO:0006955| immune response CNR2;FCGR3A;FCGR2C;OPRD1;C1QC;C1R;FCGR3B;FCGR2B;FCGR1A GO:0016032| viral reproduction FCGR2B;VDAC1;HTR2A GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;FCGR2B;ALOX15;IDO1;TRPV1 GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;FCGR2C;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;FCGR1A;SMPD1;PPARG;FCGR2B;GPR18 19247:[DB14011 DB09140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0010575| positive regulation vascular endothelial growth factor production NOX1;CYP1B1;PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1;NOX1 GO:0042542| response to hydrogen peroxide TRPA1;HBB;HBA1;GPX1;CAT;SOD1 GO:0010942| positive regulation of cell death HBA1;HBB;PTGS2 GO:0006954| inflammatory response TRPV1;NOX1;ALOX15;IDO1;PTGS2;CNR2;ALOX5;PTGS1 GO:0034765| regulation of ion transmembrane transport NOX1;CACNA1I;CACNA1G;CACNA1H GO:0007165| signal transduction PLA2G1B;CACNA1I;NOX1;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0006811| ion transport NOX1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3 GO:0051291| protein heterooligomerization GLRB;HBA1;GLRA1;HBB GO:0008217| regulation of blood pressure NOX1;HBB;PPARG;PTGS1;SOD1;PTGS2 GO:0046330| positive regulation of JNK cascade NOX1;TRPV4 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;NOX1 GO:1902177| SOD1;NOX1 GO:0043312| neutrophil degranulation ALOX5;CAT;HBB GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;NOX1;CYP1B1;CRYZ;CYP2C9;CYP1A1;MT-CO1 GO:0071455| cellular response to hyperoxia PPARG;NOX1 GO:0006801| superoxide metabolic process NOX1;SOD1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;NOX1 GO:0042554| superoxide anion generation NOX1;SOD1 GO:0009060| aerobic respiration MT-CO1;CAT GO:0007568| aging CYP1A1;MT-CO1;CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;MT-CO1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;HBB;TRPV1 GO:0098869| GSR;HBA1;HBB;CAT;PTGS1;GPX1;PTGS2 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;NOX1;GLRB;TRPV1 GO:0042744| hydrogen peroxide catabolic process HBB;HBA1;GPX1;CAT GO:0046688| response to copper ion MT-CO1;AANAT;SOD1 19248:[DB14011 DB01237] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01237|Bromodiphenhydramine HRH1;SLC22A6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HRH1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;SLC22A6;ABCC1;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;HTR2A GO:0007613| memory CHRNA7;HTR2A;CNR1;HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;HRH1 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HRH1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0098656| SLC22A6;VDAC1 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;HRH1;TRPV1;ALOX15;IDO1 GO:0008542| visual learning HRH1;HMGCR 19249:[DB14011 DB08259] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;EPHX2;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0006874| cellular calcium ion homeostasis EPHX2;GPR12;HTR2A;CHRNA7;TRPV4;TRPM8 GO:0010628| positive regulation of gene expression TRPV4;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2;EPHX2 GO:0072593| reactive oxygen species metabolic process SOD1;EPHX2 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1;EPHX2 GO:0009636| response to toxin CYP1A1;CYP1B1;EPHX2;CAT;GPX1 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;EPHX2;HMGCR;PTGS2;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;EPHX2;PTGS1 GO:0008152| metabolic process ACAT1;EPHX2;SMPD1 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;ALOX5;PTGS1;EPHX2;CNR2;PTGS2 19250:[DB14011 DB01738] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01738|Phosphorylcolamine PRKCB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PRKCB;PPARG GO:0006874| cellular calcium ion homeostasis CHRNA7;PRKCB;GPR12;HTR2A;TRPM8;TRPV4 GO:0002376| immune system process PRKCB;IDO1 GO:0006915| apoptotic process PRKCB;GPX1;VDAC1 GO:0045766| positive regulation of angiogenesis CHRNA7;PRKCB;CYP1B1 GO:0001666| response to hypoxia CHRNA7;CAT;PRKCB;CYP1A1 GO:0006351| transcription, DNA-dependent PRKCB;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;PRKCB GO:0042953| lipoprotein transport PPARG;PRKCB GO:0035556| intracellular signal transduction PLA2G1B;PRKCB GO:0006816| calcium ion transport TRPV3;CACNA1H;PRKCB;TRPV2;CHRNA7;CACNA1G;TRPA1;CACNA1I;TRPV4;TRPV1;TRPM8 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;PRKCB GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;PRKCB;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A 19251:[DB14011 DB03978] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03978|Tyrosinal tyrS;YARS;YARS common genes common pathways GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;YARS;CACNA1I;PLA2G1B GO:0006915| apoptotic process GPX1;YARS;VDAC1 19252:[DB14011 DB08197] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08197|(5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;PTGS2;OPRM1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;HSP90AA1;PLA2G1B;CACNA1I GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;TRPV3;SOD1 GO:0009409| response to cold TRPA1;HSP90AA1;PPARG;TRPM8 19253:[DB14011 DB07919] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;MAOA;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1 19254:[DB14011 DB03945] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways GO:0050830| defense response to Gram-positive bacterium PLA2G1B;CRP GO:0010628| positive regulation of gene expression TRPV4;CRP GO:0097756| PTGS2;HMGCR;CRP GO:0006954| inflammatory response CRP;TRPV1;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0032930| positive regulation of superoxide anion generation CRP;SOD1 GO:0010745| negative regulation of macrophage derived foam cell differentiation CRP;PPARG 19255:[DB14011 DB03736] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03736|2-Cyclopropylmethylenepropanal REN common genes common pathways GO:0048469| cell maturation PPARG;REN GO:0008217| regulation of blood pressure PPARG;REN;PTGS1;PTGS2;SOD1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;IDO1;REN;CYP1A1 GO:0001822| kidney development REN;CAT GO:0035902| response to immobilization stress CYP1A2;REN;CYP1A1;PPARG GO:0042493| response to drug ABCG2;TRPA1;REN;PPARG;CYP1A1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0051591| response to cAMP AANAT;REN GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;REN;TRPA1;PPARG;CYP1A1 19256:[DB14011 DB09064] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09064|Ciprofibrate PPARA common genes common pathways GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT;PPARA GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0019216| regulation of lipid metabolic process PPARA;CNR1;HMGCR;PPARG;CYP1A1 GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;PPARA;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1 GO:0007507| heart development PPARA;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0048511| rhythmic process PPARG;PPARA;AANAT GO:0001666| response to hypoxia CYP1A1;PPARA;CAT;CHRNA7 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0006631| fatty acid metabolic process PPARA;PTGS2;PTGS1;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0050728| negative regulation of inflammatory response CNR2;PPARA GO:0042060| wound healing ALOX15;PPARA;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PPARA 19257:[DB14011 DB03451] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;PPARG;PLA2G1B GO:0006367| transcription initiation from RNA polymerase II promoter VDR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;VDR GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CHRNA7;VDR;TRPM8;TRPV4 GO:0046697| decidualization VDR;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG GO:0010628| positive regulation of gene expression TRPV4;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG GO:0006351| transcription, DNA-dependent VDR;PPARG GO:0007595| lactation VDR;SLC29A1 GO:0006816| calcium ion transport TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1;TRPV2;VDR;CHRNA7;CACNA1H;TRPV3 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;VDR GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;VDR;PTGS2;OPRM1 19258:[DB14011 DB12118] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12118|Sotatercept ACVR2A common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;ACVR2A GO:0007283| spermatogenesis ACVR2A;SOD1;CNR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ACVR2A;PLA2G1B 19259:[DB14011 DB02039] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways GO:0016032| viral reproduction VDAC1;HTR2A;KAT5 GO:0006351| transcription, DNA-dependent PPARG;KAT5 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;KAT5 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;KAT5 GO:0006355| regulation of transcription, DNA-dependent PPARG;KAT5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter KAT5;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter KAT5;PPARG;PLA2G1B 19260:[DB14011 DB05234] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05234|LGD2941 AR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;AR GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;AR;CHRNA7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0006810| transport AR;TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0010468| regulation of gene expression AR;CYP1A2 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006351| transcription, DNA-dependent AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;AR;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;AR;PPARG;CYP1B1 GO:0008283| cell proliferation CYP1A1;GPX1;AR;HTR1A GO:0007548| sex differentiation AR;CYP17A1 19261:[DB14011 DB03016] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03016|CRA_1801 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 19262:[DB14011 DB08659] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08659|2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide CA2 common genes common pathways GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG 19263:[DB14011 DB04757] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006955| immune response OPRD1;CNR2;PNP GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PNP;PPARG;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT;PNP 19264:[DB14011 DB03435] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways GO:0043312| neutrophil degranulation GYG1;CAT;ALOX5 GO:0043085| positive regulation of catalytic activity SOD1;B3GAT3 GO:0006139| nucleobase-containing compound metabolic process CMPK1;SLC29A1 GO:0015949| nucleobase-containing small molecule interconversion CMPK1;GSR 19265:[DB14011 DB04244] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04244|(2R)-2-(3-Biphenylyl)-N-{(2R)-2-hydroxy-3-[(2-pyridinylsulfonyl)amino]propyl}-4-methylpentanamide CTSK common genes common pathways GO:1903146| VDAC1;CTSK GO:0045453| bone resorption GPR55;CTSK 19266:[DB14011 DB02267] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02267|Argininosuccinate ASL;argG common genes common pathways 19267:[DB14011 DB08159] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways GO:0042493| response to drug CAT;CYP1A2;PTGS2;TOP1;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0007623| circadian rhythm TOP1;AANAT GO:0048511| rhythmic process AANAT;TOP1;PPARG GO:0016032| viral reproduction VDAC1;HTR2A;TOP1 19268:[DB14011 DB08101] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;TTR 19269:[DB14011 DB12688] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways GO:0045471| response to ethanol CAT;EEF2;SOD1;CNR1;OPRM1;HMGCR GO:0042542| response to hydrogen peroxide TRPA1;SOD1;GPX1;EEF2;CAT GO:0034976| response to endoplasmic reticulum stress ALOX15;EEF2 GO:0007155| cell adhesion CD22;CYP1B1 GO:0043312| neutrophil degranulation ALOX5;EEF2;CAT GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;EEF2;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0007568| aging CAT;EEF2;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;EEF2;CAT 19270:[DB14011 DB02282] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways GO:0035722| interleukin-12-mediated signaling pathway SOD1;MTAP GO:0006139| nucleobase-containing compound metabolic process MTAP;SLC29A1 19271:[DB14011 DB11869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11869|Valspodar SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLCO1B3;SLCO1B1 GO:0006811| ion transport TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;SLCO1B3;GLRA3;SLCO1B1;CACNA1H;TRPV3 19272:[DB14011 DB06039] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06039|PA-1050040 gag common genes common pathways 19273:[DB14011 DB02311] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways GO:0070588| calcium ion transmembrane transport TRPV1;CACNA1I;TRPV4;TRPM8;FKBP1A;CACNA1G;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1 GO:0006936| muscle contraction CACNA1H;FKBP1A;GLRA1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;FKBP1A;TRPV1;TRPA1 GO:1902991| CHRNA7;FKBP1A GO:0031000| response to caffeine FKBP1A;PPARG 19274:[DB14011 DB04069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways GO:0006915| apoptotic process DAPK1;GPX1;VDAC1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;DAPK1;SOD1;GPX1;CAT GO:1902042| GPX1;DAPK1 GO:0007165| signal transduction CHRNA7;HTR2A;DAPK1;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0035556| intracellular signal transduction PLA2G1B;DAPK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;DAPK1 19275:[DB14011 DB00178] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug ABCC1;SMPD1;BCHE;TRPA1;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0001822| kidney development CAT;ACE GO:0009612| response to mechanical stimulus PPARG;BDKRB1;TRPV4 GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;CYP1A1;BDKRB1;IDO1 GO:0030308| negative regulation of cell growth PPARG;BDKRB1 GO:0007283| spermatogenesis CNR1;SOD1;ACE GO:0055085| transmembrane transport TRPV2;SLC15A2;CACNA1H;TRPV3;ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;SLC15A1;CACNA1G;ABCC1 GO:0006810| transport TRPV2;SLC15A2;ABCG2;TRPV1;CACNA1I;SLC15A1;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;BDKRB1 GO:0002446| neutrophil mediated immunity PLA2G1B;ACE GO:0006954| inflammatory response PTGS2;CNR2;PTGS1;ALOX5;BDKRB1;TRPV1;IDO1;ALOX15 GO:0045776| negative regulation of blood pressure BDKRB1;CNR1 GO:0019233| sensory perception of pain BDKRB1;TRPA1;TRPV1;OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1 GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;BCHE;PPARG;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;ACE;PTGS1 GO:0006811| ion transport CACNA1G;SLC15A1;GLRA1;TRPA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;SLC15A2;TRPV2;CHRNA7 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;BDKRB1 GO:0060047| heart contraction ACE;GPX1;SOD1 GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;BDKRB1;OPRM1;HTR2A GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 19276:[DB14011 DB00592] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00592|Piperazine GABRB3;CYP2D6 common genes CYP2D6 common pathways GO:0043523| regulation of neuron apoptosis GPX1;GABRB3 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0007605| sensory perception of sound SOD1;GPX1;GABRB3 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;GABRB3;TRPV2 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;GABRB3 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0034220| ion transmembrane transport CHRNA7;GABRB3;GLRA3;GLRB;TRPV1;GLRA1;TRPA1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0051100| negative regulation of binding CYP2D6 GO:1902476| GLRB;GLRA1;GABRB3;GLRA3 GO:0043524| negative regulation of neuron apoptosis SOD1;GABRB3 GO:0006821| chloride transport GLRB;GLRA1;GABRB3;GLRA3 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;GABRB3;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0006811| ion transport TRPV2;GABRB3;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 19277:[DB14011 DB01160] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0065009| regulation of molecular function PTGIR;TRPV1 GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;PTGFR;PTGIR;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PTGIR GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCG2 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;GPX1;CAT GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;SLC22A2;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;SLC22A8;GLRA3;CACNA1H;TRPV3;SLCO3A1;SLC22A7;SLC22A11;CHRNA7;TRPV2 GO:0098656| SLC22A7;SLC22A8;VDAC1;SLC22A6 GO:0006812| cation transport TRPM8;SLC22A2 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;PTGFR;PTGIR;CYP1A1;IDO1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;PTGFR GO:0008284| positive regulation of cell proliferation CHRNA7;PTGFR;HTR1A;HTR2A;PTGS2;HMGCR GO:0032355| response to estradiol stimulus CAT;PTGFR;PTGS2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PTGIR;GPR18;PPARG;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PTGFR GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0055085| transmembrane transport TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;SLC22A2;ABCG2;SLCO2A1;ABCC1;SLC22A6;CACNA1G;TRPA1;TRPV2;SLC22A11;SLC22A7;SLCO3A1;TRPV3;CACNA1H;SLC22A8 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGIR;CNR1;OPRD1;OPRM1;CNR2 GO:0010628| positive regulation of gene expression TRPV4;PTGFR 19278:[DB14011 DB13996] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1;ATP1A1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;GLRA3;ATP1A1;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;GLRA3;ATP1A1 GO:0086002| ATP1A1;CACNA1G GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;ATP1A1;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2 19279:[DB14011 DB09571] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09571|Levmetamfetamine PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 19280:[DB14011 DB00815] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00815|Sodium lauryl sulfate ALB common genes common pathways GO:0001895| retina homeostasis ALB;SOD1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;ALB GO:0002576| platelet degranulation ALB;SOD1 19281:[DB14011 DB03253] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 19282:[DB14011 DB00925] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0007565| female pregnancy ADRA2B;ADRA2C;IDO1 GO:0002027| regulation of heart rate CACNA1G;CALM1 GO:0035556| intracellular signal transduction ADRA1B;ADRA1A;PLA2G1B GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0009409| response to cold ADRB2;TRPA1;PPARG;TRPM8 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRA1D;ADRA1B;ADRB2;CNR1 GO:0051592| response to calcium ion CALM1;AANAT GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ADRB2 GO:0050873| brown fat cell differentiation PTGS2;ADRB2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;ADRA1A;OPRM1;PTGS2 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0006812| cation transport SLC22A1;SLC22A2;TRPM8 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;PTGS2;ADRA1B GO:0045777| positive regulation of blood pressure ADRA2B;CNR1 GO:0006855| drug transmembrane transport ABCG2;SLC22A2;ABCC1;SLC22A1;SLC22A3 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;SLC22A3;TRPM8;SLC22A2;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPA1;GLRA1;SLC22A1;CACNA1G GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADRA2C GO:0008283| cell proliferation ADRA1D;CYP1A1;GPX1;ADRA1B;HTR1A GO:0007165| signal transduction PPARG;GPR18;ADRA1D;SMPD1;ADRA2A;PLA2G1B;CACNA1I;ADRA1A;HTR1A;GPR55;ADRA2C;HTR2A;GPR12;CNR1;ADRB2;ADRA2B;OPRM1;CNR2;OPRD1;ADRA1B;CHRNA7 GO:0009725| response to hormone stimulus ADRA1A;ACAT1 GO:0001819| positive regulation of cytokine production ADRA2A;SOD1 GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;ADRA2C;HTR2A;ADRA1A;ADRA1D GO:0045453| bone resorption ADRB2;GPR55 GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRM1;OPRD1 GO:0050796| regulation of insulin secretion ADRA2A;ADRA2C;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;HTR2A;OPRM1;ADRA1A;TRPV4;TRPV1;ADRA1D GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ADRA1A;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0035307| positive regulation of protein dephosphorylation SMPD1;CALM1 GO:0002576| platelet degranulation CALM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;ADRA1B;ADRA1D;ADRA1A GO:0002024| diet induced thermogenesis ADRB2;TRPV1;TRPV4 GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A GO:0007202| activation of phospholipase C activity HTR2A;GPR55;ADRA1A GO:0000187| activation of MAPK activity PLA2G1B;ADRA2B;SOD1;CHRNA7 GO:0006915| apoptotic process ADRA1A;VDAC1;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;ADRA1A;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0055085| transmembrane transport SLC22A3;CACNA1H;TRPV3;TRPV2;CALM1;CACNA1G;SLC22A1;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;SLC22A2 GO:0006936| muscle contraction GLRA1;CACNA1H;CALM1 GO:0042593| glucose homeostasis ADRA1B;CNR1;ADRA2A;TRPV4;PPARG GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A1 GO:0007568| aging CYP1A1;ADRA1A;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;ADRB2;ADRA2B;HTR1A;GPR55;ADRA2C;ADRA1B;CALM1;ADRA1D;GPR18;PPARG;ADRA1A;ADRA2A 19283:[DB14011 DB12418] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12418|Saccharin CA3 common genes common pathways GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;CA3;SOD1;PTGS2 GO:0045471| response to ethanol CAT;SOD1;CNR1;CA3;HMGCR;OPRM1 19284:[DB14011 DB08162] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08162|Fasudil PKIA;PRKACA;ROCK1;ROCK2 common genes common pathways GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0007165| signal transduction PPARG;GPR18;SMPD1;ROCK1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0006939| smooth muscle contraction ROCK1;ROCK2;HTR2A GO:0002027| regulation of heart rate CACNA1G;PRKACA GO:0035556| intracellular signal transduction ROCK1;PLA2G1B;ROCK2 GO:0042752| regulation of circadian rhythm ROCK2;PPARG GO:1902430| CHRNA7;ROCK1 GO:0001934| positive regulation of protein phosphorylation ROCK2;CHRNA7 GO:0043524| negative regulation of neuron apoptosis ROCK1;SOD1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2;PRKACA GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;GPR18;ROCK2;PPARG;ROCK1 GO:0048511| rhythmic process AANAT;PPARG;ROCK2 GO:0010628| positive regulation of gene expression ROCK2;ROCK1;TRPV4 GO:0006915| apoptotic process ROCK1;VDAC1;GPX1 GO:0043312| neutrophil degranulation ROCK1;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;PKIA;TRPV4 GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 GO:0016525| negative regulation of angiogenesis ROCK1;PPARG;ROCK2 19285:[DB14011 DB07837] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways GO:0034220| ion transmembrane transport CHRNA7;GLRA3;GLRB;TRPV1;SGK1;TRPA1;GLRA1 GO:0006915| apoptotic process SGK1;VDAC1;GPX1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;SGK1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;SGK1 GO:0035556| intracellular signal transduction SGK1;PLA2G1B 19286:[DB14011 DB01811] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways GO:0002376| immune system process IDO1;LTF GO:0019731| antibacterial humoral response LTF;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LTF GO:0006355| regulation of transcription, DNA-dependent PPARG;LTF GO:0045087| innate immune response PPARG;LTF GO:0043312| neutrophil degranulation ALOX5;LTF;CAT GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;LTF;CAT GO:0061844| LTF;PLA2G1B GO:0001895| retina homeostasis LTF;SOD1 GO:0006811| ion transport TRPV2;CHRNA7;LTF;TRPV3;CACNA1H;GLRA3;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0002227| innate immune response in mucosa LTF;PLA2G1B GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;LTF GO:0001503| ossification ALOX15;LTF GO:0006351| transcription, DNA-dependent PPARG;LTF 19287:[DB14011 DB00449] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ADRB2;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;ADRA2A;ADRA1A;GPR18;PPARG GO:0009611| response to wounding CYP1A1;ACHE;GPX1 GO:0007568| aging ADRA1A;CYP1A1;CAT;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2 GO:0042593| glucose homeostasis PPARG;ADRA2A;TRPV4;CNR1 GO:0006915| apoptotic process VDAC1;ADRA1A;GPX1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;ADRA1A;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0007202| activation of phospholipase C activity ADRA1A;GPR55;HTR2A GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0002024| diet induced thermogenesis ADRB2;TRPV4;TRPV1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ADRA1A GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;PLA2G1B GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;BCHE;ABCG2;ADRA1A;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;ADRA1A;TRPV1;HTR2A;OPRM1 GO:0050796| regulation of insulin secretion CNR1;ADRA2A GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;ADRA1A GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0045453| bone resorption GPR55;ADRB2 GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0007165| signal transduction PLA2G1B;ADRA1A;CACNA1I;ADRA2A;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;ADRB2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;ACHE GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation BCHE;PPARG;CYP1B1;ADRA1A;OPRM1;PTGS2 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0050873| brown fat cell differentiation PTGS2;ADRB2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ADRB2 GO:0009409| response to cold ADRB2;TRPM8;PPARG;TRPA1 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0035556| intracellular signal transduction PLA2G1B;ADRA1A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB2;CNR1 GO:0007399| nervous system development GLRB;SMPD1;ACHE 19288:[DB14011 DB12061] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes HTR1A common pathways GO:0051209| release of sequestered calcium ion into cytosol DRD2;TRPV1;TRPA1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;DRD4;GPR55;HTR1A;HTR2A;GPR12;CNR1;PPARG;DRD3;GPR18;DRD2 GO:0006874| cellular calcium ion homeostasis TRPV4;DRD2;TRPM8;DRD3;CHRNA7;GPR12;HTR2A;DRD4 GO:0007210| serotonin receptor signaling pathway HTR1A;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade DRD2;TRPV4;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;DRD4;CHRNA7 GO:0042220| response to cocaine CNR1;OPRM1;DRD2;DRD3;SMPD1 GO:0014062| regulation of serotonin secretion HTR1A GO:0048511| rhythmic process PPARG;DRD4;AANAT GO:0009416| response to light stimulus DRD2;AANAT GO:0014059| regulation of dopamine secretion DRD3;DRD2;HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;DRD2 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;DRD4 GO:0001666| response to hypoxia CYP1A1;DRD2;CHRNA7;CAT GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;DRD2;TRPV1;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0007612| learning DRD3;VDAC1;PTGS2 GO:0007611| learning or memory DRD3;CHRNA7;CNR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;PPARG;TRPV4;TRPV1 GO:0007628| adult walking behavior GLRB;DRD2;GLRA1 GO:0050795| regulation of behavior HTR2A;HTR1A GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0007626| locomotory behavior SOD1;OPRM1;DRD2;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;DRD3;PLA2G1B;DRD2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;DRD3 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD3;OPRM1 GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;DRD2;PPARG;CYP1A1;DRD3;TRPA1;SMPD1;ABCC1 GO:0035640| exploration behavior HTR1A GO:0043278| response to morphine OPRM1;CNR1;DRD2;DRD3 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0035094| response to nicotine CHRNA7;CNR1;DRD2 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;DRD3 GO:0040014| regulation of multicellular organism growth SOD1;DRD3 GO:0001975| response to amphetamine DRD2;DRD3;SOD1;DRD4;CNR2 GO:0007610| behavior HTR2A;HTR1A GO:0007165| signal transduction SMPD1;DRD3;GPR18;PPARG;DRD2;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;DRD4;GPR55;HTR1A;CHRNA7 GO:1900273| CHRNA7;DRD2 GO:0050482| arachidonic acid secretion DRD4;DRD2;PLA2G1B;DRD3 GO:0014854| response to inactivity DRD2;CAT GO:0008344| adult locomotory behavior OPRD1;DRD4 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0009636| response to toxin DRD2;CYP1B1;CYP1A1;CAT;GPX1 GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A GO:0001662| behavioral fear response VDAC1;DRD4;HTR1A GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;DRD2;CYP1B1 GO:0042053| regulation of dopamine metabolic process DRD4;HTR1A GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0045776| negative regulation of blood pressure CNR1;DRD3;DRD2 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;DRD2;DRD3 GO:0048678| response to axon injury SOD1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0001659| temperature homeostasis TRPV1;DRD2;GPX1;HTR2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0042310| vasoconstriction HTR1A GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0042428| serotonin metabolic process HTR1A GO:0048148| behavioral response to cocaine DRD3;DRD2;HTR2A;DRD4 GO:0048149| behavioral response to ethanol DRD4;OPRM1;DRD2 GO:0042752| regulation of circadian rhythm PPARG;DRD4 GO:0033674| positive regulation of kinase activity DRD4;HTR2A GO:0008542| visual learning HMGCR;DRD3;DRD2 GO:0001964| startle response GLRB;DRD2;GLRA1 19289:[DB14011 DB06215] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0002576| platelet degranulation SOD1;TF GO:0043312| neutrophil degranulation FTL;FTH1;ALOX5;CAT GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;ALOX5;GPX1;PTGS1;FTH1 GO:0006811| ion transport GLRA3;TRPV3;TF;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1 GO:0001895| retina homeostasis SOD1;TF GO:0008285| negative regulation of cell proliferation FTH1;PTGS2;OPRM1;CYP1B1;PPARG GO:0006955| immune response FTH1;CNR2;OPRD1 GO:0006879| cellular iron ion homeostasis FTL;FTH1;TF;SOD1;ABCG2 19290:[DB14011 DB01444] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes OPRM1;OPRD1 common pathways GO:0032094| response to food OPRM1;CYP1A1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0043278| response to morphine CNR1;OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0042060| wound healing OPRM1;ALOX15 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;TRPV1;GLRB GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0007626| locomotory behavior SOD1;OPRM1 GO:0007218| neuropeptide signaling pathway GLRB;GLRA1;OPRD1;OPRM1;GLRA3 GO:0070848| response to growth factor stimulus OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0042220| response to cocaine SMPD1;OPRM1;CNR1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0038003| opioid receptor signaling pathway OPRM1;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;CACNA1G;GLRA1;GLRB;VDAC1 GO:0010629| negative regulation of gene expression OPRD1 GO:0048149| behavioral response to ethanol OPRM1 GO:0006955| immune response CNR2;OPRD1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0007600| sensory perception TRPV2;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0045471| response to ethanol SOD1;CNR1;OPRM1;HMGCR;CAT GO:0000060| protein import into nucleus, translocation OPRD1 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1;TRPV1;TRPA1 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0042755| eating behavior OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0008344| adult locomotory behavior OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV4;TRPV1 GO:0071315| cellular response to morphine OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1 GO:0070588| calcium ion transmembrane transport TRPV3;CACNA1H;OPRM1;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1 GO:0044849| OPRM1 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 19291:[DB14011 DB05417] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05417|GW 468816 GLRA1 common genes GLRA1 common pathways GO:0006820| anion transport VDAC1;GLRA1 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;CACNA1H GO:0006936| muscle contraction GLRA1;CACNA1H GO:0051260| protein homooligomerization GLRA1;ACAT1;GLRA3 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;TRPV1;GLRB GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1 GO:0071230| cellular response to amino acid stimulus GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;TRPV1;GLRB GO:0001508| regulation of action potential GLRA1;CACNA1G GO:0007628| adult walking behavior GLRB;GLRA1 GO:0007340| acrosome reaction GLRB;GLRA1 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;GLRB;GLRA1 GO:0050884| neuromuscular process controlling posture GLRA1 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0050905| neuromuscular process GLRB;GLRA1 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1 GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0060012| synaptic transmission, glycinergic GLRB;GLRA1;GLRA3 GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0006821| chloride transport GLRA3;GLRB;GLRA1 GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I GO:0051291| protein heterooligomerization GLRB;GLRA1 GO:0071294| cellular response to zinc ion GLRA1 GO:0097305| GLRA1 GO:0071361| cellular response to ethanol GLRA1 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;HTR2A;GLRA3;OPRD1;OPRM1 GO:1902476| GLRA3;GLRB;GLRA1 GO:0060013| righting reflex GLRA1;GLRB GO:0001964| startle response GLRA1;GLRB 19292:[DB14011 DB02338] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0051262| protein tetramerization AASS;HMGCR;CAT GO:0098869| GSR;PTGS1;GPX1;TXNRD1;CAT;PTGS2 GO:0022900| electron transport chain IDO1;GSR;CYP1A2;TXNRD1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;AASS;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;DPYD;PTGS1;ALOX5;GPX1;TXNRD1 GO:0034599| cellular response to oxidative stress GSR;CAT;GPX1;TXNRD1;SOD1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;TXNRD1 GO:0015949| nucleobase-containing small molecule interconversion GSR;TXNRD1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;TXNRD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;TXNRD1;CNR1;HMGCR GO:0045454| cell redox homeostasis GPX1;TXNRD1;GSR GO:0008152| metabolic process AASS;SMPD1;ACAT1 19293:[DB14011 DB01973] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;PRSS2 19294:[DB14011 DB00373] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes CYP2C19;CYP2D6 common pathways GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0045453| bone resorption ADRB2;GPR55 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;ADRB2;CNR1;GPR12;HTR2A;GPR55;HTR1A;ADRB1;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0001659| temperature homeostasis TRPV1;ADRB1;GPX1;HTR2A GO:0009409| response to cold ADRB2;PPARG;TRPA1;ADRB1;TRPM8 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPA1;TRPV1 GO:0050873| brown fat cell differentiation PTGS2;ADRB2;ADRB1 GO:0051100| negative regulation of binding CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0055085| transmembrane transport TRPM8;ABCG2;ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G;TRPV2;TRPV3;CACNA1H GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;ADRB1;GPR55;HTR1A;ADRB2;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0006810| transport ABCC1;ABCG2;ABCB1;CACNA1I;TRPV1;TRPV2 GO:0019369| arachidonic acid metabolic process FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PLA2G1B;PPARG GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0002024| diet induced thermogenesis ADRB1;TRPV4;TRPV1;ADRB2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 19295:[DB14011 DB09462] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0097061| dendritic spine organization ARF1;CHRNA7 GO:0001975| response to amphetamine TRDMT1;SOD1;CNR2 GO:0007566| embryo implantation TGFBR2;SOD1;PTGS2;PPARD GO:0050796| regulation of insulin secretion ITPR1;CNR1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;GSTP1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0050482| arachidonic acid secretion PLA2G2E;PLA2G1B GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;CACNA1G;ITPR1;TRPM8;TRPV4;CACNA1I;TRPV1 GO:0065009| regulation of molecular function TRPV1;ITPR1 GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:0007420| brain development TGFBR2;ACAT1 GO:0007165| signal transduction ITPR1;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HPGDS;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;ARF1;CACNA1G;CACNA1I GO:0006633| fatty acid biosynthetic process HPGDS;PTGS1;PTGS2;PLA2G1B GO:0014070| response to organic cyclic compound ACAT1;AANAT;TGFBR2;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0009636| response to toxin CAT;GPX1;CYP1A1;GSTP1;CYP1B1 GO:0008283| cell proliferation CYP1A1;HTR1A;PPARD;GPX1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;ITPR1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0001516| prostaglandin biosynthetic process HPGDS;PTGS1;PTGS2 GO:0001523| retinoid metabolic process NAPEPLD;ALDH1A1 GO:0019395| fatty acid oxidation PPARD;PPARG GO:0060612| adipose tissue development ACAT1;PPARD GO:0001890| placenta development PPARD;SOD1;PPARG GO:0006749| glutathione metabolic process GSR;GSTP1;SOD1;GPX1 GO:0045600| positive regulation of fat cell differentiation PPARD;HTR2A;PPARG GO:0009791| post-embryonic development CYP1A2;ITPR1 GO:0036150| PLA2G1B;PLA2G2E GO:0014823| response to activity PPARD;CAT GO:0008285| negative regulation of cell proliferation TGFBR2;PTGS2;OPRM1;PPARG;CYP1B1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0007584| response to nutrient HMGCR;TGFBR2;CNR1;PPARG GO:0043627| response to estrogen stimulus PPARG;TGFBR2 GO:0036149| PLA2G1B;PLA2G2E GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0006351| transcription, DNA-dependent PPARD;PPARG GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARD GO:0045471| response to ethanol GSTP1;CAT;CNR1;SOD1;CYP2E1;HMGCR;OPRM1 GO:0002666| positive regulation of T cell tolerance induction TGFBR2;IDO1 GO:0006693| prostaglandin metabolic process HPGDS;PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;GSTP1 GO:0008152| metabolic process NAGA;ALDH1A1;ACAT1;SMPD1;PAPSS1;GSTP1 GO:0042572| retinol metabolic process ALDH1A1;CYP1B1 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G2E;PLA2G1B;TRPV1;PPARG;CYP2C9;ISYNA1;GPX1;NAAA;PTGS1;HPGDS;CYP3A4;NAPEPLD;PPARD;HMGCR;CYP1A2;PTGS2 GO:0036148| PLA2G2E;PLA2G1B GO:0007507| heart development PPARG;PPARD;TGFBR2 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:0019371| cyclooxygenase pathway HPGDS;PTGS1;PTGS2 GO:0006816| calcium ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;TRPV1;TRPV4;CACNA1I;TRPM8;ITPR1;CACNA1G;TRPA1 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TRPV1;PLA2G2E;ALOX15;IDO1 GO:2000778| positive regulation of interleukin-6 secretion PAEP;TRPV4 GO:0048565| digestive tract development TGFBR2;CYP1A1 GO:1904706| GSTP1;PPARG GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A7;HMGCR;CYP2E1;CYP3A4 GO:0032355| response to estradiol stimulus GSTP1;PTGS2;CYP1A2;CAT GO:0051209| release of sequestered calcium ion into cytosol ITPR1;TRPV1;TRPA1;HTR2A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PPARD;CAT GO:0046697| decidualization PPARD;PTGS2 GO:0007568| aging HMGCR;PTGS2;TGFBR2;CNR1;SOD1;HTR2A;NAPEPLD;CAT;CYP1A1 GO:0071456| cellular response to hypoxia PTGS2;PPARD;OPRD1;SLC29A1 GO:0010468| regulation of gene expression TGFBR2;CYP1A2 GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSTP1;GSR GO:0032720| negative regulation of tumor necrosis factor production GPR18;GSTP1;CHRNA7 GO:0031100| organ regeneration PPARG;GSTP1;TGFBR2 GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0043085| positive regulation of catalytic activity ARF1;SOD1 GO:0036152| PLA2G2E;PLA2G1B GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0016042| lipid catabolic process PLA2G1B;PLA2G2E;DAGLA;NAPEPLD GO:0045766| positive regulation of angiogenesis TGFBR2;CHRNA7;CYP1B1 GO:0006915| apoptotic process GPX1;PPARD;TGFBR2;VDAC1;ITPR1;PAEP GO:0050714| positive regulation of protein secretion ARF1;PLA2G1B GO:0055085| transmembrane transport TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;ITPR1;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0010193| response to ozone CAT;CYP2E1 GO:0001666| response to hypoxia TGFBR2;CAT;CHRNA7;CYP1A1;ITPR1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0015758| glucose transport PLA2G1B;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG GO:0010033| response to organic substance SOD1;TGFBR2;CYP1A2;PTGS2;PPARD;CYP1A1;PPARG;TRPA1 GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;PLA2G2E GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0036151| PLA2G2E;PLA2G1B GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0000302| response to reactive oxygen species GSTP1;CAT;GPX1;SOD1 GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PPARD;TGFBR2 GO:0042060| wound healing ALOX15;OPRM1;PPARD;TGFBR2 GO:0034599| cellular response to oxidative stress GPX1;CAT;SOD1;GSTP1;GSR GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0030324| lung development TGFBR2;CYP1A2 GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2E GO:0035722| interleukin-12-mediated signaling pathway ARF1;SOD1 GO:0009612| response to mechanical stimulus PPARG;TRPV4;TGFBR2 GO:0043066| negative regulation of apoptotic process GSTP1;SOD1;HMGCR;PPARD;PTGS2;CAT;GPX1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2;CYP2E1 GO:0032259| methylation CYP1A2;TRDMT1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;PPARD;HMGCR;HTR1A;HTR2A;TGFBR2 GO:0007626| locomotory behavior SOD1;OPRM1;HPGDS GO:0043312| neutrophil degranulation GSTP1;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;TRPV1;TRPV4;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD GO:0006631| fatty acid metabolic process ALOX15;PTGS2;HPGDS;PTGS1 GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARG GO:0042493| response to drug CYP2E1;TGFBR2;HTR2A;SOD1;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;ADH1B;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP2E1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALDH1A1;PTGS1;ALOX5;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;TGFBR2 GO:0010243| response to organic nitrogen TRPV1;PTGS2;CYP2E1 GO:0050728| negative regulation of inflammatory response PPARD;CNR2 GO:0033189| response to vitamin A CYP1A1;PPARG;PPARD;CAT GO:0007015| actin filament organization TRPV4;PLA2G1B;ARF1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD GO:0009062| fatty acid catabolic process PPARD;FAAH 19296:[DB14011 DB02508] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process FDPS;HMGCR GO:0008299| isoprenoid biosynthetic process FDPS;HMGCR GO:0008202| steroid metabolic process CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1;FDPS;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0006694| steroid biosynthetic process FDPS;HMGCR;CYP17A1 GO:0006695| cholesterol biosynthetic process FDPS;HMGCR GO:0008203| cholesterol metabolic process FDPS;CAT;HMGCR GO:0016032| viral reproduction FDPS;HTR2A;VDAC1 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;CYP2C9;PPARG;GPX1;NAAA;PTGS1;FDPS;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0016126| sterol biosynthetic process HMGCR;FDPS 19297:[DB14011 DB04113] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04113|N-Formylpiperidine ADH1C common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;ADH1C;CAT;ALOX5;PTGS1;GPX1 19298:[DB14011 DB00319] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0055085| transmembrane transport TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;SLC22A6;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLC22A8 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport GLRA3;SLC22A8;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB GO:0098656| SLC22A8;SLC22A6;VDAC1 19299:[DB14011 DB02473] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02473|6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0001666| response to hypoxia CAT;CHRNA7;PLAU;CYP1A1 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;PLAU;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 19300:[DB14011 DB07664] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07664|5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE CSNK1G3;SLK;CAMK4;CLK3;ABL2 common genes common pathways GO:0035556| intracellular signal transduction PLA2G1B;CAMK4 GO:0010976| positive regulation of neuron projection development ABL2;CNR1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;ALOX15;IDO1;CAMK4;TRPV1 GO:0007165| signal transduction CHRNA7;CSNK1G3;HTR2A;CNR1;GPR12;ABL2;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CAMK4;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;HTR2A;ABL2 GO:0007155| cell adhesion ABL2;CYP1B1 GO:0045087| innate immune response ABL2;PPARG GO:0071300| cellular response to retinoic acid ABL2;PPARG GO:0042127| regulation of cell proliferation PTGS2;ABL2;PTGS1 GO:0033081| regulation of T cell differentiation in thymus CAMK4;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CAMK4 GO:0002376| immune system process IDO1;CAMK4 GO:0006915| apoptotic process GPX1;SLK;VDAC1 19301:[DB14011 DB08493] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08493|5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID MMP7 common genes common pathways GO:0031667| response to nutrient levels SOD1;MMP7 GO:0071260| cellular response to mechanical stimulus MMP7;PTGS2 GO:0044849| MMP7;OPRM1 GO:0060135| maternal process involved in female pregnancy CNR1;MMP7 GO:0007568| aging CYP1A1;MMP7;CAT;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2 19302:[DB14011 DB03850] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03850|Jaspisamide A ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 GO:0006936| muscle contraction ACTA1;CACNA1H;GLRA1 GO:0010628| positive regulation of gene expression TRPV4;ACTA1 GO:0048741| skeletal muscle fiber development ACTA1;GPX1 GO:0009612| response to mechanical stimulus PPARG;TRPV4;ACTA1 19303:[DB14011 DB09340] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09340|Tyropanoic acid GUSB common genes common pathways GO:0008152| metabolic process GUSB;ACAT1;SMPD1 GO:0043312| neutrophil degranulation CAT;GUSB;ALOX5 19304:[DB14011 DB06248] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06248|Amelubant LTB4R2;LTB4R common genes common pathways GO:0007165| signal transduction LTB4R2;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;LTB4R;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;LTB4R2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PTGS1;ALOX5;PTGS2;LTB4R;CNR2 GO:0006955| immune response CNR2;LTB4R;OPRD1 GO:0006936| muscle contraction CACNA1H;LTB4R;GLRA1 GO:0007186| G-protein coupled receptor signaling pathway LTB4R2;GPR18;PPARG;OPRD1;OPRM1;CNR2;LTB4R;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0007218| neuropeptide signaling pathway GLRA3;OPRM1;LTB4R;OPRD1;GLRA1;LTB4R2;GLRB GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;LTB4R;OPRM1;LTB4R2 19305:[DB14011 DB00716] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0071380| cellular response to prostaglandin E stimulus PTGDR;PPARG GO:0007165| signal transduction PLA2G1B;CYSLTR1;CACNA1I;SMPD1;GPR18;PPARG;HSP90AA1;FPR1;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;PTGDR;CYSLTR2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;CYSLTR1;TRPV4;FPR1;HTR2A;OPRM1 GO:0006955| immune response CYSLTR2;OPRD1;CNR2 GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1;CYSLTR1 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;CNR2;PTGS2;PTGDR;FPR1;ALOX5;PTGS1 GO:0010942| positive regulation of cell death PTGS2;CYSLTR2 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0009409| response to cold TRPM8;TRPA1;PPARG;HSP90AA1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;FPR1 GO:0030431| sleep CACNA1I;SLC29A1;HTR2A;PTGDR GO:0007166| cell surface receptor linked signaling pathway TRPV1;CYSLTR1;TRPA1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;CYSLTR2 GO:0000187| activation of MAPK activity PLA2G1B;FPR1;CHRNA7;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;CYSLTR2;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HSP90AA1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;PTGDR;CYSLTR2;GPR55;HTR1A;OPRD1;CNR2;OPRM1;FPR1;GPR18;PPARG;CYSLTR1 GO:0060326| cell chemotaxis FPR1;ABCC1 GO:0007218| neuropeptide signaling pathway GLRA3;CYSLTR2;OPRD1;OPRM1;CYSLTR1;GLRB;GLRA1 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0043312| neutrophil degranulation HSP90AA1;FPR1;ALOX5;CAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger FPR1;OPRM1;OPRD1;CYSLTR2;HTR2A;CYSLTR1 19306:[DB14011 DB04685] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways GO:0070207| protein homotrimerization DUT;TRPM8 GO:0015949| nucleobase-containing small molecule interconversion DUT;GSR GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1;DUT GO:0006139| nucleobase-containing compound metabolic process SLC29A1;DUT GO:0001889| liver development ACAT1;DUT;CYP1A1 19307:[DB14011 DB04072] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04072|Alpha-Methylisocitric Acid ACO2 common genes common pathways GO:0001889| liver development CYP1A1;ACO2;ACAT1 GO:0008152| metabolic process ACO2;SMPD1;ACAT1 GO:0035900| response to isolation stress NAPEPLD;ACO2 19308:[DB14011 DB00030] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0043066| negative regulation of apoptotic process IGF1R;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle RB1;PTGS2 GO:0002576| platelet degranulation SOD1;SYTL4 GO:0008284| positive regulation of cell proliferation INSR;CHRNA7;IGF1R;PTGS2;HMGCR;HTR1A;HTR2A GO:0007218| neuropeptide signaling pathway GLRB;GLRA1;CPE;OPRD1;OPRM1;GLRA3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;RB1 GO:0043312| neutrophil degranulation CTSD;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;RB1 GO:0007155| cell adhesion CYP1B1;IGFBP7 GO:0030308| negative regulation of cell growth NOV;PPARG GO:0007612| learning INSR;VDAC1;PTGS2 GO:0032526| response to retinoic acid IGFBP7;PPARG GO:0050728| negative regulation of inflammatory response CNR2;NOV GO:0060326| cell chemotaxis ABCC1;NOV GO:0051897| positive regulation of protein kinase B signaling cascade INSR;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;INSR;RB1 GO:0006355| regulation of transcription, DNA-dependent RB1;PPARG;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;INSR GO:0042593| glucose homeostasis PPARG;INSR;TRPV4;CNR1 GO:0051260| protein homooligomerization IDE;GLRA1;ACAT1;GLRA3 GO:0007605| sensory perception of sound GPX1;LRP2;SOD1 GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0010468| regulation of gene expression NOV;CYP1A2 GO:0042359| vitamin D metabolic process CYP3A4;LRP2;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent RB1;PPARG GO:0051262| protein tetramerization IGF1R;HMGCR;CAT GO:0050714| positive regulation of protein secretion SYTL4;PLA2G1B GO:0000187| activation of MAPK activity SOD1;CHRNA7;INSR;PLA2G1B GO:0006915| apoptotic process VDAC1;RB1;GPX1 GO:0050769| positive regulation of neurogenesis OPRM1;LRP2 GO:0035556| intracellular signal transduction INSR;PLA2G1B GO:0008152| metabolic process PCSK1;IDE;SMPD1;ACAT1;CPE GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;LRP2;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG GO:0042953| lipoprotein transport PPARG;LRP2 GO:0007507| heart development LRP2;PPARG GO:0007399| nervous system development LRP2;SMPD1;GLRB;PCSK2 GO:0006357| regulation of transcription from RNA polymerase II promoter RB1;PPARG GO:0006351| transcription, DNA-dependent PPARG;RB1 GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0001525| angiogenesis CYP1B1;PTGS2;NOV GO:0016032| viral reproduction RB1;HTR2A;VDAC1;IDE GO:0006955| immune response OPRD1;CNR2;IGF1R GO:0009408| response to heat IGFBP7;TRPV1;TRPV2;TRPV3;SOD1 GO:0051289| protein homotetramerization TRPA1;IDE;CRYZ;TRPM8;TRPV1;CAT GO:0048565| digestive tract development RB1;CYP1A1 GO:0071603| endothelial cell-cell adhesion CYP1B1;NOV GO:0010629| negative regulation of gene expression OPRD1;RB1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;INSR GO:0045445| myoblast differentiation HMGCR;RB1 GO:0032870| cellular response to hormone stimulus IGFBP7;CACNA1H GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;IGF1R GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;IGF1R;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0046718| entry of virus into host cell IDE;HTR2A GO:0007566| embryo implantation SOD1;PTGS2;IGFBP7 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7;INSR GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;INSR GO:0051291| protein heterooligomerization GLRB;GLRA1;IDE GO:0001523| retinoid metabolic process NAPEPLD;LRP2 GO:0045740| positive regulation of DNA replication PLA2G1B;INSR;IGF1R GO:0008285| negative regulation of cell proliferation RB1;PTGS2;OPRM1;PPARG;IGFBP7;CYP1B1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG;IGFBP7 GO:0008283| cell proliferation CYP1A1;LRP2;GPX1;HTR1A 19309:[DB14011 DB08482] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08482|[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER MMP1 common genes common pathways GO:0016032| viral reproduction HTR2A;MMP1;VDAC1 19310:[DB14011 DB13967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13967|Patent Blue ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0098869| GSR;ALB;CAT;PTGS1;GPX1;PTGS2 19311:[DB14011 DB07696] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;CASP3;PTGS2;CYP1A2 GO:0006919| activation of caspase activity CASP3;PPARG GO:0009411| response to UV CASP3;CAT GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;GPX1;CASP3;CAT GO:0043065| positive regulation of apoptotic process CASP3;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0045165| cell fate commitment CASP3;PPARG GO:0007507| heart development CASP3;PPARG GO:0043200| response to amino acid stimulus GLRA3;CASP3;GLRB GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0006915| apoptotic process CASP3;GPX1;VDAC1 GO:0001666| response to hypoxia CASP3;CAT;CHRNA7;CYP1A1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CASP3;CYP1A1;PPARG;TRPA1 GO:0009611| response to wounding CASP3;GPX1;CYP1A1 GO:0032355| response to estradiol stimulus CASP3;CAT;PTGS2;CYP1A2 GO:0007605| sensory perception of sound SOD1;CASP3;GPX1 GO:0042493| response to drug CAT;CASP3;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0071407| cellular response to organic cyclic compound CASP3;CYP1A1;CYP1B1 GO:0035094| response to nicotine CNR1;CHRNA7;CASP3 GO:0032496| response to lipopolysaccharide CASP3;CNR1;PTGS2;CNR2;OPRM1;CYP1A2;IDO1;CYP1A1 GO:0042060| wound healing ALOX15;CASP3;OPRM1 GO:0007611| learning or memory CNR1;CASP3;CHRNA7 GO:0046677| response to antibiotic CYP1A1;CASP3;SOD1 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CASP3;CAT 19312:[DB14011 DB13884] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways GO:0002576| platelet degranulation SOD1;F8 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP2C9;CYP1A1;CRYZ;F8;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1 19313:[DB14011 DB00275] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00275|Olmesartan AGTR1;ABCC2;SLCO1B3;SLCO1B1;ABCB11 common genes common pathways GO:0007565| female pregnancy ABCC2;IDO1 GO:0009408| response to heat ABCC2;TRPV1;TRPV2;SOD1;TRPV3 GO:0035725| sodium ion transmembrane transport ABCB11;CACNA1H;CACNA1G;CACNA1I GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCC1 GO:0006811| ion transport TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;SLCO1B1;GLRA3;SLCO1B3;TRPV3;CACNA1H GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;AGTR1;TRPV4;TRPV1 GO:0050729| positive regulation of inflammatory response AGTR1;TRPV4 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;AGTR1;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;ABCC2 GO:0099133| ABCC2;ABCC1 GO:0060326| cell chemotaxis ABCC1;AGTR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGTR1;OPRM1;OPRD1;HTR2A GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;ABCC2;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;AGTR1;PTGS2 GO:0001822| kidney development AGTR1;CAT GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;ABCC2;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1;ABCB11;SLCO1B1;SLCO1B3;TRPV3;CACNA1H;TRPV2 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;AGTR1;GPR18 GO:0006810| transport TRPV2;ABCB11;CACNA1I;TRPV1;ABCC2;ABCG2;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway AGTR1;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1;ABCC2 19314:[DB14011 DB03650] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03650|(3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One PIM1 common genes common pathways GO:0006915| apoptotic process PIM1;GPX1;VDAC1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;PIM1;SOD1 GO:0008283| cell proliferation GPX1;PIM1;HTR1A;CYP1A1 19315:[DB14011 DB14600] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14600|Edetate disodium anhydrous ADA;CYP1A2;PON3;CYP19A1 common genes CYP1A2 common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin CYP1A1;PON3;CYP1B1;CAT;GPX1 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0001890| placenta development SOD1;ADA;PPARG GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0001889| liver development CYP1A1;ADA;ACAT1 GO:0016125| sterol metabolic process CYP19A1;CYP17A1;CYP1B1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0042542| response to hydrogen peroxide GPX1;ADA;CAT;SOD1;TRPA1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;PTGS1;NAAA;GPX1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0001666| response to hypoxia ADA;CHRNA7;CAT;CYP1A1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0007568| aging CYP1A1;ADA;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1 GO:0010468| regulation of gene expression CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;CYP19A1 GO:0042493| response to drug ADA;CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP19A1;CYP2C9;CYP1A1 GO:0006694| steroid biosynthetic process CYP19A1;CYP17A1;HMGCR GO:0019372| lipoxygenase pathway GPX1;ALOX5;PTGS2;PON3;ALOX15 GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0043278| response to morphine ADA;CNR1;OPRM1 GO:0033197| response to vitamin E ADA;CAT GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;IDO1;CYP1A1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2;ADA GO:0043066| negative regulation of apoptotic process CAT;ADA;GPX1;SOD1;HMGCR;PTGS2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0007155| cell adhesion ADA;CYP1B1 19316:[DB14011 DB06457] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06457|Tecastemizole KCNH2 common genes common pathways GO:0055085| transmembrane transport TRPV2;KCNH2;CACNA1H;TRPV3;ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;GLRA1;CACNA1G;GLRB GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;KCNH2;GLRA3;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0034765| regulation of ion transmembrane transport CACNA1H;KCNH2;CACNA1I;CACNA1G GO:0086010| CACNA1G;CACNA1I;CACNA1H;KCNH2 GO:0086091| CACNA1G;KCNH2 19317:[DB14011 DB05413] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05413|Tifuvirtide SERPINA5 common genes common pathways GO:0007283| spermatogenesis SOD1;CNR1;SERPINA5 19318:[DB14011 DB07117] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways GO:0043388| positive regulation of DNA binding MMP9;PPARG GO:0043312| neutrophil degranulation MMP9;CAT;ALOX5 GO:0043066| negative regulation of apoptotic process MMP9;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0007566| embryo implantation MMP9;PTGS2;SOD1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;MMP9 GO:0001503| ossification MMP9;ALOX15 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;MMP9;SMPD1;CNR1;SOD1;PTGS2 GO:0001934| positive regulation of protein phosphorylation MMP9;CHRNA7 19319:[DB14011 DB06371] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06371|Siplizumab CD2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;CD2 GO:0007155| cell adhesion CD2;CYP1B1 GO:0006915| apoptotic process VDAC1;GPX1;CD2 19320:[DB14011 DB06602] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06602|Reslizumab IL5 common genes common pathways GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;IL5;TRPV1;IDO1;ALOX15 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL5 GO:0006955| immune response IL5;OPRD1;CNR2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL5 GO:0045893| positive regulation of transcription, DNA-dependent IL5;PPARG GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;IL5 GO:0008284| positive regulation of cell proliferation CHRNA7;IL5;HTR2A;HTR1A;HMGCR;PTGS2 19321:[DB14011 DB04119] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways GO:0010666| positive regulation of cardiac muscle cell apoptosis CAMK2A;HMGCR GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAMK2A;CAT GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;CACNA1H;TRPV3;CHRNA7;TRPV2;CAMK2A GO:0007399| nervous system development GLRB;SMPD1;CAMK2A GO:0035556| intracellular signal transduction PLA2G1B;CAMK2A 19322:[DB14011 DB07930] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;NAAA;PTGS1;GPX1;PPARG;CYP2C9;ACOX1;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B GO:0006693| prostaglandin metabolic process ACOX1;PTGS2;PTGS1 GO:0008152| metabolic process SMPD1;ACOX1;ACAT1 GO:0055088| lipid homeostasis PPARG;ACOX1 GO:0019395| fatty acid oxidation ACOX1;PPARG GO:0019216| regulation of lipid metabolic process ACOX1;PPARG;CYP1A1;CNR1;HMGCR GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;ACOX1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 GO:0006631| fatty acid metabolic process ACOX1;ALOX15;PTGS2;PTGS1 GO:0006635| fatty acid beta-oxidation ACAT1;ACOX1 GO:0007283| spermatogenesis SOD1;CNR1;ACOX1 19323:[DB14011 DB11949] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11949|Vestipitant TACR1 common genes common pathways GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;TACR1;GLRA1;CACNA1G;VDAC1;GLRB GO:0006954| inflammatory response PTGS2;CNR2;TACR1;PTGS1;ALOX5;ALOX15;IDO1;TRPV1 GO:0009408| response to heat SOD1;TACR1;TRPV3;TRPV2;TRPV1 GO:0048266| behavioral response to pain TACR1;TRPV1 GO:0019233| sensory perception of pain OPRD1;PTGS2;CNR2;TACR1;OPRM1;CNR1;HTR2A;TRPV1;TRPA1 GO:0045471| response to ethanol CAT;HMGCR;TACR1;OPRM1;SOD1;CNR1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;TACR1;CYP1A1;PPARG;TRPA1 GO:0042755| eating behavior OPRD1;TACR1;OPRM1 GO:0045777| positive regulation of blood pressure CNR1;TACR1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TACR1 GO:0008217| regulation of blood pressure PTGS1;TACR1;PTGS2;SOD1;PPARG GO:0060083| smooth muscle contraction involved in micturition TRPV1;TACR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;TACR1;HTR2A GO:0043117| positive regulation of vascular permeability TACR1;TRPV4 GO:0045907| positive regulation of vasoconstriction HTR2A;TACR1;PTGS2 GO:0009725| response to hormone stimulus ACAT1;TACR1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;CNR1;GPR12;HTR2A;TACR1;CNR2;OPRM1;OPRD1;CHRNA7 GO:0035094| response to nicotine CNR1;TACR1;CHRNA7 GO:0043278| response to morphine OPRM1;TACR1;CNR1 GO:0048265| response to pain TRPV1;TRPA1;TACR1 GO:0007611| learning or memory TACR1;CNR1;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;TACR1;OPRD1;HTR2A GO:0010193| response to ozone CAT;TACR1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;TACR1;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PPARG;GPR18 GO:0032355| response to estradiol stimulus CAT;TACR1;PTGS2;CYP1A2 19324:[DB14011 DB07500] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways GO:0036150| PLA2G1B;PLA2G2E GO:0050482| arachidonic acid secretion PLA2G2E;PLA2G1B GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;PLA2G2E;ALOX15;IDO1 GO:0036148| PLA2G1B;PLA2G2E GO:0006629| lipid metabolic process TRPV1;PLA2G1B;PLA2G2E;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0036149| PLA2G1B;PLA2G2E GO:0006644| phospholipid metabolic process PLA2G1B;PLA2G2E;NAPEPLD GO:0016042| lipid catabolic process NAPEPLD;PLA2G1B;PLA2G2E;DAGLA GO:0036152| PLA2G1B;PLA2G2E GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2E GO:0036151| PLA2G1B;PLA2G2E 19325:[DB14011 DB03195] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03195|Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways GO:0046686| response to cadmium ion CAT;DTYMK GO:0071363| cellular response to growth factor stimulus DTYMK;TRPV1;OPRD1;CAT GO:0043627| response to estrogen stimulus PPARG;DTYMK GO:0015949| nucleobase-containing small molecule interconversion GSR;DTYMK GO:0008283| cell proliferation GPX1;HTR1A;DTYMK;CYP1A1 GO:0045445| myoblast differentiation DTYMK;HMGCR 19326:[DB14011 DB01704] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process CTRB1;ABCC1 19327:[DB14011 DB12874] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12874|Quizartinib FLT3 common genes common pathways GO:0043406| positive regulation of MAP kinase activity FLT3;HTR2A GO:0031100| organ regeneration PPARG;FLT3 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FLT3 GO:0010243| response to organic nitrogen PTGS2;FLT3;TRPV1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;FLT3;HTR2A;CHRNA7 GO:0071345| cellular response to cytokine stimulus TRPV1;FLT3 19328:[DB14011 DB05750] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05750|AVE-1625 CNR1 common genes CNR1 common pathways GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0051966| regulation of synaptic transmission, glutamatergic CNR1 GO:0038171| CNR2;GPR55;CNR1 GO:0045777| positive regulation of blood pressure CNR1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7 GO:0050796| regulation of insulin secretion CNR1 GO:0099553| CNR1 GO:0031999| negative regulation of fatty acid beta-oxidation CNR1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG GO:0010976| positive regulation of neuron projection development CNR1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1 GO:0045776| negative regulation of blood pressure CNR1 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CAT GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1 GO:0060259| regulation of feeding behavior CNR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR2;CNR1 GO:0002866| positive regulation of acute inflammatory response to antigenic stimulus CNR1 GO:0007283| spermatogenesis SOD1;CNR1 GO:0051001| negative regulation of nitric-oxide synthase activity CNR2;CNR1 GO:0042220| response to cocaine SMPD1;OPRM1;CNR1 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0007568| aging CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0045759| negative regulation of action potential CNR2;CNR1 GO:0043278| response to morphine CNR1;OPRM1 GO:0035094| response to nicotine CHRNA7;CNR1 GO:0033004| negative regulation of mast cell activation CNR2;CNR1 GO:0007413| axonal fasciculation CNR1 GO:0043271| negative regulation of ion transport CNR1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1 GO:0033602| negative regulation of dopamine secretion CNR1 GO:0060405| regulation of penile erection CNR1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0060135| maternal process involved in female pregnancy CNR1 GO:0007611| learning or memory CHRNA7;CNR1 19329:[DB14011 DB07127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07127|{4-[2,2-BIS(5-METHYL-1,2,4-OXADIAZOL-3-YL)-3-PHENYLPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways GO:0001525| angiogenesis PTGS2;PTPRB;CYP1B1 GO:0043312| neutrophil degranulation ALOX5;CAT;PTPRB 19330:[DB14011 DB05394] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05394|Corticorelin DBH common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;DBH;PTGS1 GO:0007626| locomotory behavior DBH;OPRM1;SOD1 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;DBH;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1 GO:0048265| response to pain DBH;TRPV1;TRPA1 GO:0042593| glucose homeostasis TRPV4;PPARG;DBH;CNR1 GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;OPRD1;OPRM1;HTR2A;GLRA3;DBH GO:0048149| behavioral response to ethanol OPRM1;DBH GO:0008542| visual learning DBH;HMGCR GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7;DBH GO:0001975| response to amphetamine DBH;CNR2;SOD1 GO:0045907| positive regulation of vasoconstriction DBH;PTGS2;HTR2A 19331:[DB14011 DB04115] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04115|Berberine BIRC5 common genes common pathways GO:0007605| sensory perception of sound BIRC5;GPX1;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;BIRC5 GO:0006915| apoptotic process VDAC1;BIRC5;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;BIRC5;HTR2A;HTR1A;HMGCR;PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;BIRC5;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;BIRC5 GO:0006351| transcription, DNA-dependent PPARG;BIRC5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;BIRC5;PTGS2 19332:[DB14011 DB02660] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02660|Filaminast PDE4B common genes common pathways GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4B GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PDE4B;PPARG;GPR18 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;PDE4B;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CHRNA7 19333:[DB14011 DB00465] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00465|Ketorolac PTGS2;PTGS1 common genes PTGS1;PTGS2 common pathways GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PTGS2;CNR2;ALOX5;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;NAAA;GPX1;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP2C9;CYP1A1;CRYZ;GPX1;ALOX5;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 19334:[DB14011 DB00720] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes PTGS2 common pathways GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0050796| regulation of insulin secretion SLC25A6;CNR1;SLC25A4;SLC25A5 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;PTGS1;ALOX5 GO:0016032| viral reproduction VDAC1;SLC25A5;SLC25A4;HTR2A;SLC25A6 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;PPARG;CYP2C9;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPA1;TRPV1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0055085| transmembrane transport TRPV2;TRPV3;SLC25A6;CACNA1H;SLC25A5;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;SLC25A4;ABCC1;CACNA1G;TRPA1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0006915| apoptotic process VDAC1;SLC25A6;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:1902219| PTGS2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0007568| aging CYP1A1;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD GO:0046697| decidualization PTGS2 GO:0006810| transport TRPV1;CACNA1I;SLC25A5;ABCG2;SLC25A4;ABCC1;TRPV2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C9;CYP1A1;CRYZ;ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;SLC25A5 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;CYP1A1;IDO1 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0071284| cellular response to lead ion PTGS2 19335:[DB14011 DB01147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLC15A2;CACNA1H;TRPV3;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;SLC15A1;GLRA1;TRPA1;CACNA1G GO:0098656| SLC22A6;VDAC1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;ALB GO:0055085| transmembrane transport SLC15A2;CACNA1H;TRPV3;TRPV2;SLC15A1;TRPA1;SLC22A6;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I GO:0006810| transport TRPV2;SLC15A2;ABCG2;CACNA1I;TRPV1;SLC15A1;ABCC1 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0098869| PTGS2;CAT;PTGS1;GPX1;GSR;ALB 19336:[DB14011 DB02932] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02932|(R)-Bicalutamide AR common genes common pathways GO:0007165| signal transduction AR;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0008283| cell proliferation CYP1A1;GPX1;AR;HTR1A GO:0007548| sex differentiation AR;CYP17A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0006810| transport AR;TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0010468| regulation of gene expression CYP1A2;AR GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV4;TRPV1 GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR 19337:[DB14011 DB00573] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes PTGS2;PTGS1;PPARG common pathways GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0061614| PPARG GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ALOX5;PTGS1;CNR2;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:1904706| PPARG GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0006351| transcription, DNA-dependent PPARG;PPARA GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1;TRPA1;TRPV1 GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG;PPARA GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;PPARA;HMGCR;PTGS2;CYP1A2 GO:0033280| response to vitamin D PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0006919| activation of caspase activity PPARG GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0032868| response to insulin stimulus PPARA;AANAT;CAT;TRPV4 GO:0042633| hair cycle PTGS2 GO:0001895| retina homeostasis ALB;SOD1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;PPARG GO:0055088| lipid homeostasis PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:1905461| PPARG GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1;PPARA GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG GO:0006631| fatty acid metabolic process ALOX15;PPARA;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0030224| monocyte differentiation PPARG GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0071455| cellular response to hyperoxia PPARG GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0050728| negative regulation of inflammatory response CNR2;PPARA GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0009750| response to fructose stimulus PTGS2 GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0042060| wound healing ALOX15;PPARA;OPRM1 GO:0007612| learning PTGS2;VDAC1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071284| cellular response to lead ion PTGS2 GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PPARA GO:0002576| platelet degranulation ALB;SOD1 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;ALB GO:0071300| cellular response to retinoic acid PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;TRPV1;TRPV4;PPARG GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation PPARG;ACAT1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0001666| response to hypoxia PPARA;CAT;CHRNA7;CYP1A1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0031000| response to caffeine PPARG GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:1902219| PTGS2 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0097756| HMGCR;PTGS2 GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0015909| long-chain fatty acid transport PPARG GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CYP1A1 GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0033993| response to lipid PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| PTGS1;GPX1;CAT;PTGS2;ALB;GSR GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0043388| positive regulation of DNA binding PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG 19338:[DB14011 DB00120] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0009635| response to herbicide TH;CYP1A1 GO:0031667| response to nutrient levels SOD1;TH GO:0008016| regulation of heart contraction TH;CACNA1H GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;TH;CNR1;CAT GO:0008152| metabolic process PAH;SMPD1;ACAT1 GO:0042136| neurotransmitter biosynthetic process TH;DAGLA;PAH GO:0071312| cellular response to alkaloid TH;TRPV1 GO:0007507| heart development TH;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;TH;ACAT1;AANAT;TAT;TRPA1;PPARG;CYP1A1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC7A8;GPX1;CAT GO:0042755| eating behavior OPRD1;OPRM1;TH GO:0010043| response to zinc ion TH;AANAT GO:0014823| response to activity CAT;TH GO:0001975| response to amphetamine CNR2;SOD1;TH GO:0043434| response to peptide hormone stimulus TH;TRPV1 GO:0051384| response to glucocorticoid stimulus TAT;PTGS2 GO:0050890| cognition CHRNA7;TH GO:0007601| visual perception TH;GLRA1;CRYZ;GLRB;CYP1B1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;TH GO:0007613| memory CHRNA7;PTGS2;CNR1;TH;HTR2A GO:0051412| response to corticosterone stimulus TH;AANAT GO:0006631| fatty acid metabolic process ALOX15;PTGS1;TH;PTGS2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;TH;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0055114| oxidation-reduction process PAH;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;TH;ALOX5;GPX1;PTGS1;CAT GO:0035900| response to isolation stress TH;NAPEPLD GO:0035094| response to nicotine TH;CNR1;CHRNA7 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;TH;OPRM1;CYP1A2;PTGS2;CNR2 GO:0007612| learning PTGS2;TH;VDAC1 GO:0071333| cellular response to glucose stimulus SLC29A1;TH GO:0007626| locomotory behavior TH;SOD1;OPRM1 GO:0070848| response to growth factor stimulus OPRM1;TH GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2;TH GO:0055085| transmembrane transport TRPV1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;SLC16A10;CACNA1H GO:0001666| response to hypoxia CYP1A1;TH;CAT;CHRNA7 GO:0009416| response to light stimulus TH;AANAT GO:0071363| cellular response to growth factor stimulus OPRD1;TH;CAT;TRPV1 GO:0032355| response to estradiol stimulus CAT;TH;PTGS2;CYP1A2 GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;SLC7A8 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;TAT GO:0007605| sensory perception of sound TH;SOD1;GPX1 19339:[DB14011 DB07677] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 19340:[DB14011 DB09329] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways GO:0007155| cell adhesion VWF;CYP1B1 GO:0002576| platelet degranulation SOD1;VWF GO:0009611| response to wounding CYP1A1;VWF;GPX1 GO:0051260| protein homooligomerization GLRA3;VWF;ACAT1;GLRA1 19341:[DB14011 DB07592] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07592|(2R)-3-Methyl-1-phenyl-2-butanyl [(2S)-1-oxo-2-hexanyl]carbamate CTSK common genes common pathways GO:1903146| CTSK;VDAC1 GO:0045453| bone resorption GPR55;CTSK 19342:[DB14011 DB04117] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04117|4-(N,N-Dimethylamino)Cinnamoyl-Coa ECHS1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;CYP2D6;ECHS1;DAGLA;ALOX15;CYP2C9;PPARG GO:0008152| metabolic process ECHS1;SMPD1;ACAT1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15;ECHS1 GO:0006635| fatty acid beta-oxidation ECHS1;ACAT1 19343:[DB14011 DB02758] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways GO:0050482| arachidonic acid secretion PLA2G2E;PLA2G1B GO:0036150| PLA2G2E;PLA2G1B GO:0036149| PLA2G2E;PLA2G1B GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;NAAA;GPX1;PTGS1;CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G2E;TRPV1;PLA2G1B GO:0036148| PLA2G2E;PLA2G1B GO:0006954| inflammatory response TRPV1;PLA2G2E;ALOX15;IDO1;CNR2;PTGS2;ALOX5;PTGS1 GO:0036152| PLA2G2E;PLA2G1B GO:0016042| lipid catabolic process NAPEPLD;PLA2G2E;PLA2G1B;DAGLA GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G2E;PLA2G1B GO:0036151| PLA2G2E;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2E 19344:[DB14011 DB07509] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes PPARG common pathways GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;PPARG;GPR18 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0071455| cellular response to hyperoxia PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0030224| monocyte differentiation PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation ACAT1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0032526| response to retinoic acid PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0030308| negative regulation of cell growth PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0055088| lipid homeostasis PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0006919| activation of caspase activity PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1 GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0048469| cell maturation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG 19345:[DB14011 DB01647] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01647|Daxalipram PDE4B common genes common pathways GO:0007165| signal transduction PDE4B;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;PDE4B GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B 19346:[DB14011 DB00869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes CYP2C9;CYP3A4 common pathways GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;CA3 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CA2;PPARG;CYP1A1;TRPA1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0036378| CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0001822| kidney development CAT;CA2 GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0019627| urea metabolic process CYP2C9 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;PTGS1;NAAA;GPX1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;SOD1;CNR1;CA3 GO:0043603| cellular amide metabolic process CYP2C9 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4 19347:[DB14011 DB02589] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02589|Se-Ethyl-Isoselenourea NOS3 common genes common pathways GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;NOS3;PTGS2;OPRM1 GO:1902042| GPX1;NOS3 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0045776| negative regulation of blood pressure NOS3;CNR1 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0009408| response to heat TRPV2;SOD1;TRPV3;NOS3;TRPV1 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;NOS3 GO:0042311| vasodilation NOS3;GPX1 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development NOS3;CYP1A2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;NOS3;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR 19348:[DB14011 DB04276] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04276|N-[N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-Butyl]-Guanidine CAPN1 common genes common pathways GO:0043312| neutrophil degranulation CAPN1;CAT;ALOX5 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;CAPN1;HMGCR 19349:[DB14011 DB03849] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction PDE4B;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;PDE4D;OPRM1;CNR2 GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0002027| regulation of heart rate CACNA1G;PDE4D GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;PDE4D;OPRD1;CNR2;OPRM1;GPR18;PPARG;PDE4B GO:0007568| aging CYP1A1;CAT;HMGCR;PDE4D;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD GO:0030593| neutrophil chemotaxis PDE4D;PDE4B;PLA2G1B 19350:[DB14011 DB07701] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways GO:0008283| cell proliferation GPX1;ACHE;HTR1A;CYP1A1 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0007517| muscle organ development CACNA1H;ACHE GO:0007155| cell adhesion CYP1B1;ACHE 19351:[DB14011 DB02822] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02822|Para-Bromobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;ADH1C 19352:[DB14011 DB07561] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1;DHODH GO:0007595| lactation SLC29A1;DHODH GO:0007565| female pregnancy IDO1;DHODH GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1;DHODH GO:0031000| response to caffeine PPARG;DHODH GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;DHODH;CAT GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;DHODH;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0042594| response to starvation DHODH;ACAT1;PPARG 19353:[DB14011 DB00147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00147|Pyridoxal PDXK common genes common pathways GO:0008283| cell proliferation GPX1;PDXK;HTR1A;CYP1A1 GO:0043312| neutrophil degranulation PDXK;CAT;ALOX5 19354:[DB14011 DB01541] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01541|Boldenone AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0008283| cell proliferation CYP1A1;AR;GPX1;HTR1A GO:0007548| sex differentiation AR;CYP17A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;OPRM1;PTGS2 GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;AR;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0008284| positive regulation of cell proliferation AR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV1;TRPV4 GO:0007283| spermatogenesis AR;SOD1;CNR1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;AR;TRPV2 GO:0010468| regulation of gene expression AR;CYP1A2 19355:[DB14011 DB00133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;AGXT GO:0007420| brain development ACAT1;SRR GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;SRR;PPARG;CYP1A1;TRPA1 GO:0046513| ceramide biosynthetic process SPTLC1;SMPD1;SPTLC2 GO:0006351| transcription, DNA-dependent SARS;PPARG GO:0008152| metabolic process SMPD1;CBS;SRR;SPTLC2;ACAT1 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;SPTLC1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG;GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;SPTLC2;NAPEPLD;CYP3A4 GO:0051289| protein homotetramerization CAT;TRPA1;CRYZ;TRPM8;SRR;TRPV1 GO:0007568| aging CAT;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;SRR;CYP1A1 GO:0051591| response to cAMP AGXT;AANAT GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLC16A10;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;SRR;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter SARS;PPARG;TRPV1;TRPV4 GO:0006355| regulation of transcription, DNA-dependent PPARG;SARS GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;SRR;ABCG2 GO:0055114| oxidation-reduction process CBS;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT GO:0016525| negative regulation of angiogenesis PPARG;SARS GO:0043278| response to morphine OPRM1;CNR1;SRR 19356:[DB14011 DB07252] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07252|3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide EPHB4 common genes common pathways GO:0001525| angiogenesis PTGS2;EPHB4;CYP1B1 GO:0007155| cell adhesion EPHB4;CYP1B1 19357:[DB14011 DB05422] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05422|OPC-14523 SLC6A4 common genes common pathways GO:0007613| memory CHRNA7;SLC6A4;PTGS2;HTR2A;CNR1 GO:0007420| brain development ACAT1;SLC6A4 GO:0009636| response to toxin GPX1;SLC6A4;CAT;CYP1B1;CYP1A1 GO:0007584| response to nutrient SLC6A4;HMGCR;CNR1;PPARG GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC6A4 GO:0042310| vasoconstriction SLC6A4;HTR1A GO:0032355| response to estradiol stimulus CAT;SLC6A4;PTGS2;CYP1A2 GO:0051260| protein homooligomerization SLC6A4;ACAT1;GLRA3;GLRA1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;SLC6A4;CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0010033| response to organic substance SLC6A4;CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0001666| response to hypoxia CAT;SLC6A4;CHRNA7;CYP1A1 GO:0010628| positive regulation of gene expression SLC6A4;TRPV4 GO:0007623| circadian rhythm SLC6A4;AANAT GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;SLC6A4;CAT;PTGS2;CYP1A2;SOD1;HTR2A 19358:[DB14011 DB13749] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0045821| positive regulation of glycolysis HTR2A;PFKFB1 GO:0071277| cellular response to calcium ion ALOX15;ADCY1 GO:0035556| intracellular signal transduction ADCY1;PLA2G1B;GUCY1A2 GO:0008152| metabolic process SMPD1;ACAT1;PFKFB1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;ABL1;SMPD1;PPARG GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0042752| regulation of circadian rhythm PPARG;ADCY1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ABL1 GO:0010226| response to lithium ion ADCY1;PTGS2 GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY1;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TRPV1;TRPV4;HTR2A;OPRM1 GO:0007420| brain development ACAT1;CKB GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;ADCY1;PPARG;GPR18;GUCY1A2;SMPD1 GO:0006811| ion transport TRPV3;CACNA1H;ATP1A1;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8 GO:0032868| response to insulin stimulus TRPV4;PFKFB1;CAT;AANAT GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0008217| regulation of blood pressure PPARG;ATP1A1;SOD1;PTGS2;PTGS1 GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0042127| regulation of cell proliferation ABL1;PTGS2;PTGS1 GO:0007623| circadian rhythm ADCY1;AANAT GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0034599| cellular response to oxidative stress GSR;ABL1;SOD1;GPX1;CAT GO:0042594| response to starvation ACAT1;PFKFB1;PPARG GO:0007155| cell adhesion CYP1B1;ABL1 GO:0045087| innate immune response PPARG;ABL1 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ADCY1;ABCG2;CYP1A2;PTGS2;ATP1A1;SOD1;HTR2A;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;GPR18;PPARG;ADCY1 GO:0006979| response to oxidative stress ABL1;PTGS2;SOD1;PTGS1;GPX1;CAT GO:0031100| organ regeneration PFKFB1;PPARG GO:0048538| thymus development SOD1;ABL1 GO:0051591| response to cAMP PFKFB1;AANAT GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;GLRA3;ATP1A1 GO:0006915| apoptotic process GPX1;VDAC1;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ABL1;ALOX15 GO:0086002| ATP1A1;CACNA1G GO:0048511| rhythmic process AANAT;PPARG;ADCY1 19359:[DB14011 DB07173] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 19360:[DB14011 DB08276] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08276|trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-) MYH14 common genes common pathways GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1G;MYH14;CACNA1I GO:0007605| sensory perception of sound MYH14;GPX1;SOD1 19361:[DB14011 DB02890] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways GO:0007595| lactation SLC29A1;UMPS GO:0007565| female pregnancy IDO1;UMPS GO:0008152| metabolic process ACAT1;UMPS;SMPD1 19362:[DB14011 DB00066] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00066|Follitropin FSHR common genes common pathways GO:0007165| signal transduction FSHR;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;FSHR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FSHR GO:0007283| spermatogenesis FSHR;SOD1;CNR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;FSHR;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 19363:[DB14011 DB08809] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08809|Dichloroacetic Acid PDK1;GSTZ1 common genes common pathways GO:0098869| GSTZ1;GSR;GPX1;PTGS1;CAT;PTGS2 GO:0008283| cell proliferation PDK1;CYP1A1;GPX1;HTR1A GO:0006749| glutathione metabolic process GSTZ1;GSR;SOD1;GPX1 GO:0008631| induction of apoptosis by oxidative stress PDK1;CYP1B1;GPX1 GO:0008152| metabolic process GSTZ1;SMPD1;ACAT1 19364:[DB14011 DB11595] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11595|Atezolizumab CD274 common genes common pathways GO:0042130| negative regulation of T cell proliferation IDO1;CD274 GO:0034097| response to cytokine stimulus CD274;AANAT;PTGS2 GO:0046006| regulation of activated T cell proliferation IDO1;CD274 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;CD274;PPARG;GPR18;CACNA1I;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CD274 GO:0006955| immune response CD274;OPRD1;CNR2 GO:0032693| negative regulation of interleukin-10 production IDO1;CD274 19365:[DB14011 DB01751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0006810| transport TRPV2;TTR;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0043312| neutrophil degranulation ALOX5;CAT;TTR 19366:[DB14011 DB11135] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11135|Selenium SCLY;GSR;TXNRD1 common genes GSR common pathways GO:0022900| electron transport chain GSR;IDO1;TXNRD1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;TXNRD1;CAT GO:0034599| cellular response to oxidative stress GSR;SOD1;CAT;GPX1;TXNRD1 GO:0098869| TXNRD1;PTGS1;GPX1;CAT;PTGS2;GSR GO:0006749| glutathione metabolic process GSR;SOD1;GPX1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;TXNRD1 GO:0015949| nucleobase-containing small molecule interconversion TXNRD1;GSR GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;TXNRD1;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0045454| cell redox homeostasis GPX1;TXNRD1;GSR GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;TXNRD1;CNR1;HMGCR 19367:[DB14011 DB01836] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01836|[4-(6-Chloro-Naphthalene-2-Sulfonyl)-Piperazin-1-Yl]-(3,4,5,6-Tetrahydro-2h-[1,4']Bipyridinyl-4-Yl)-Methanone PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 19368:[DB14011 DB02774] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02774|1,3-Propandiol ARF1 common genes common pathways GO:0050714| positive regulation of protein secretion ARF1;PLA2G1B GO:0043085| positive regulation of catalytic activity SOD1;ARF1 GO:0007015| actin filament organization ARF1;TRPV4;PLA2G1B GO:0035722| interleukin-12-mediated signaling pathway ARF1;SOD1 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;ARF1;CACNA1G;CACNA1I GO:0097061| dendritic spine organization CHRNA7;ARF1 19369:[DB14011 DB04856] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes CYP3A4;CYP3A5;CYP2C9 common pathways GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CCKAR;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CCKAR;HTR2A;OPRD1;OPRM1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;CCKAR;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0032870| cellular response to hormone stimulus CACNA1H;CCKAR GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;CCKAR;HTR2A;OPRM1 GO:0007584| response to nutrient PPARG;CCKAR;CNR1;HMGCR GO:0046883| regulation of hormone secretion HTR2A;HTR1A;CCKAR GO:0019627| urea metabolic process CYP2C9 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0043603| cellular amide metabolic process CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 19370:[DB14011 DB01582] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01582|Sulfamethazine ALB common genes common pathways GO:0098869| ALB;GSR;PTGS2;PTGS1;GPX1;CAT GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0001895| retina homeostasis ALB;SOD1 19371:[DB14011 DB03944] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 19372:[DB14011 DB03413] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways GO:0001889| liver development DUT;CYP1A1;ACAT1 GO:0006139| nucleobase-containing compound metabolic process DUT;SLC29A1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1;DUT GO:0015949| nucleobase-containing small molecule interconversion GSR;DUT GO:0070207| protein homotrimerization DUT;TRPM8 19373:[DB14011 DB04466] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04466|SR12813 NR1I2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NR1I2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG GO:0006355| regulation of transcription, DNA-dependent NR1I2;PPARG GO:0008202| steroid metabolic process CYP1A1;CYP2C9;NR1I2;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2 GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;NR1I2;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG GO:0006351| transcription, DNA-dependent PPARG;NR1I2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;NR1I2;CYP2C9;CYP2C19 GO:0007165| signal transduction SMPD1;NR1I2;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 GO:0042908| xenobiotic transport ABCG2;ABCC1;NR1I2 19374:[DB14011 DB07629] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07629|N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 19375:[DB14011 DB02115] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02115|Daidzin ALDH2;ABCG2 common genes ABCG2 common pathways GO:0046415| urate metabolic process ABCG2 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0008152| metabolic process ALDH2;ACAT1;SMPD1 GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0022900| electron transport chain CYP1A2;ALDH2;GSR;IDO1 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;ALDH2;CYP3A7;CYP1A2 GO:0015886| heme transport ABCG2 GO:0033344| cholesterol efflux ABCG2 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8 GO:0006810| transport TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 19376:[DB14011 DB08786] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08786|4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AA1;TRPV1 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;HSP90AA1;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0009408| response to heat TRPV2;SOD1;TRPV3;TRPV1;HSP90AA1 GO:0009409| response to cold TRPA1;PPARG;HSP90AA1;TRPM8 19377:[DB14011 DB09310] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 19378:[DB14011 DB03706] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03706|1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane GSTM4 common genes common pathways GO:0008152| metabolic process SMPD1;GSTM4;ACAT1 GO:0006749| glutathione metabolic process SOD1;GPX1;GSTM4;GSR GO:0042178| xenobiotic catabolic process GSTM4;CRYZ 19379:[DB14011 DB08047] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08047|4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol ESR1;NCOA2 common genes common pathways GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;ESR1;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV1;TRPV4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0048511| rhythmic process PPARG;NCOA2;AANAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;NCOA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;NCOA2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV1;TRPV4;PPARG;NCOA2 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 19380:[DB14011 DB05012] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0007268| synaptic transmission SLC6A2;CACNA1G;GLRA1;GLRB;VDAC1;OPRD1;OPRM1;HTR2A;GLRA3 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;CACNA1G;SLC6A2;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0006810| transport TRPV1;CACNA1I;ABCG2;SLC6A2;ABCC1;TRPV2 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;SMPD1;SLC6A2;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0048265| response to pain TRPV1;TRPA1;SLC6A2 19381:[DB14011 DB07681] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07681|DODECANESULFONATE ION BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;PPARG;CYP1B1;PTGS2;OPRM1 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0042493| response to drug BCHE;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0007612| learning VDAC1;BCHE;PTGS2 19382:[DB14011 DB07624] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07624|1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide HSD11B1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HSD11B1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9;GPX1;ALOX5;PTGS1;HSD11B1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0030324| lung development CYP1A2;HSD11B1 GO:0008202| steroid metabolic process HSD11B1;HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP2C9;CYP1A1 GO:0006704| glucocorticoid biosynthetic process HSD11B1;CYP17A1 19383:[DB14011 DB02636] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways GO:0006954| inflammatory response TRPV1;PLA2G2E;ALOX15;IDO1;PTGS1;ALOX5;PTGS2;CNR2 GO:0036149| PLA2G2E;PLA2G1B GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PLA2G2E;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG GO:0036148| PLA2G2E;PLA2G1B GO:0036150| PLA2G1B;PLA2G2E GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2E GO:0036151| PLA2G2E;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G2E;PLA2G1B GO:0016042| lipid catabolic process DAGLA;PLA2G2E;PLA2G1B;NAPEPLD GO:0006644| phospholipid metabolic process PLA2G1B;PLA2G2E;NAPEPLD GO:0036152| PLA2G2E;PLA2G1B 19384:[DB14011 DB02084] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02084|CRA_17312 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19385:[DB14011 DB03026] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03026|Phosphoglycolohydroxamic Acid TPI1;fucA common genes common pathways GO:0008152| metabolic process SMPD1;TPI1;ACAT1 19386:[DB14011 DB03017] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03017|Lauric Acid ADH5;fabB;GM2A;fabH;HNF4A;PLA2G2A;VLDLR;GLTP;fabF;LTF;tonB;C8G;PLA2G2D;LY96;TLR4;PPARA;ALB common genes common pathways GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2A;PLA2G2D GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;LTF;CAT;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;TLR4;PPARG;PLA2G1B;HNF4A GO:0043312| neutrophil degranulation GM2A;ALOX5;LTF;CAT GO:0045087| innate immune response LY96;C8G;LTF;TLR4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VLDLR;PPARA;PPARG;TRPV1;TRPV4 GO:0030308| negative regulation of cell growth HNF4A;PPARG GO:0036151| PLA2G2D;PLA2G2A;PLA2G1B GO:0007611| learning or memory GM2A;CNR1;CHRNA7 GO:0042060| wound healing ALOX15;OPRM1;PPARA GO:0008203| cholesterol metabolic process CAT;VLDLR;HMGCR GO:0032496| response to lipopolysaccharide LY96;CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;ADH5;TLR4;CYP1A1 GO:0046330| positive regulation of JNK cascade TLR4;TRPV4 GO:0032874| positive regulation of stress-activated MAPK cascade TLR4;HMGCR GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG;HNF4A GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG;HNF4A GO:0022900| electron transport chain ADH5;IDO1;GSR;CYP1A2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PPARA;PTGS2 GO:0050830| defense response to Gram-positive bacterium LTF;PLA2G1B;PLA2G2A GO:0006355| regulation of transcription, DNA-dependent HNF4A;PPARG;LTF;PPARA GO:0019731| antibacterial humoral response LTF;PLA2G1B GO:0055114| oxidation-reduction process ADH5;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP2C9;CYP1A1;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TLR4;TRPV1 GO:0098869| CAT;GPX1;PTGS1;PTGS2;ALB;GSR GO:0002376| immune system process C8G;LY96;LTF;IDO1;TLR4 GO:0042593| glucose homeostasis HNF4A;TRPV4;PPARG;CNR1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;TLR4;CHRNA7 GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0036152| PLA2G1B;PLA2G2A;PLA2G2D GO:0006687| glycosphingolipid metabolic process GM2A;SMPD1;GLTP GO:0008202| steroid metabolic process VLDLR;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0032735| positive regulation of interleukin-12 production IDO1;TLR4 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0010628| positive regulation of gene expression TLR4;TRPV4 GO:0001666| response to hypoxia PPARA;CAT;CHRNA7;CYP1A1 GO:0006644| phospholipid metabolic process PLA2G1B;PLA2G2A;PLA2G2D;NAPEPLD GO:0042130| negative regulation of T cell proliferation IDO1;PLA2G2D GO:0048511| rhythmic process PPARG;AANAT;PPARA GO:0016042| lipid catabolic process NAPEPLD;PLA2G2D;PLA2G2A;DAGLA;PLA2G1B GO:0000187| activation of MAPK activity SOD1;CHRNA7;TLR4;PLA2G1B GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0045671| negative regulation of osteoclast differentiation GPR55;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;TLR4;PLA2G2A;ALOX15;TRPV4 GO:0006805| xenobiotic metabolic process CYP2C9;HNF4A;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0050727| regulation of inflammatory response TLR4;PTGS2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP1A2;PTGS2;HMGCR;PLA2G2D;VLDLR;PPARA;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;HNF4A;PLA2G2A;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;GM2A GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0001503| ossification ALOX15;LTF GO:0007507| heart development PPARG;PPARA GO:0007399| nervous system development VLDLR;GLRB;SMPD1 GO:0036148| PLA2G2D;PLA2G2A;PLA2G1B GO:0036149| PLA2G1B;PLA2G2A;PLA2G2D GO:0006357| regulation of transcription from RNA polymerase II promoter HNF4A;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;HNF4A;PPARA GO:0006351| transcription, DNA-dependent HNF4A;PPARG;LTF;PPARA GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;LY96 GO:0006955| immune response OPRD1;CNR2;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;PLA2G1B;LTF;CAT GO:0006954| inflammatory response LY96;ALOX5;PTGS1;PLA2G2D;PTGS2;CNR2;IDO1;ALOX15;TRPV1;TLR4 GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2A;PLA2G2D GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;VLDLR;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;TLR4;PPARG GO:0050729| positive regulation of inflammatory response TLR4;TRPV4;PLA2G2A GO:0019216| regulation of lipid metabolic process PPARA;CNR1;HMGCR;HNF4A;CYP1A1;PPARG GO:0007613| memory PTGS2;VLDLR;CNR1;HTR2A;CHRNA7 GO:0050796| regulation of insulin secretion HNF4A;CNR1 GO:0055088| lipid homeostasis PPARG;HNF4A GO:0001523| retinoid metabolic process NAPEPLD;ADH5 GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0008285| negative regulation of cell proliferation HNF4A;CYP1B1;PPARG;PTGS2;OPRM1 GO:0036150| PLA2G2A;PLA2G1B;PLA2G2D GO:0061844| PLA2G1B;LTF GO:0002227| innate immune response in mucosa LTF;PLA2G1B GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0006811| ion transport TRPV2;LTF;CHRNA7;TRPV3;CACNA1H;GLRA3;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0001895| retina homeostasis ALB;SOD1;LTF GO:0045777| positive regulation of blood pressure ADH5;CNR1 GO:0032868| response to insulin stimulus CAT;AANAT;PPARA;TRPV4 GO:0007548| sex differentiation HNF4A;CYP17A1 19387:[DB14011 DB00552] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00552|Pentostatin ADA common genes common pathways GO:0001889| liver development CYP1A1;ACAT1;ADA GO:0042542| response to hydrogen peroxide TRPA1;ADA;GPX1;CAT;SOD1 GO:0001890| placenta development SOD1;ADA;PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0030324| lung development ADA;CYP1A2 GO:0033197| response to vitamin E CAT;ADA GO:0007155| cell adhesion ADA;CYP1B1 GO:0043066| negative regulation of apoptotic process ADA;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ADA;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0043278| response to morphine ADA;CNR1;OPRM1 GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0007568| aging ADA;CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CYP1A1 GO:0001666| response to hypoxia ADA;CAT;CHRNA7;CYP1A1 19388:[DB14011 DB04436] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04436|3-Fluorotyrosine SOD2 common genes common pathways GO:0008285| negative regulation of cell proliferation CYP1B1;SOD2;PPARG;OPRM1;PTGS2 GO:0008217| regulation of blood pressure SOD2;PPARG;PTGS1;SOD1;PTGS2 GO:0043524| negative regulation of neuron apoptosis SOD2;SOD1 GO:0051289| protein homotetramerization CAT;TRPM8;SOD2;TRPV1;TRPA1;CRYZ GO:0019430| removal of superoxide radicals SOD1;SOD2 GO:0000303| response to superoxide SOD1;SOD2 GO:0006357| regulation of transcription from RNA polymerase II promoter SOD2;PPARG GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;SOD2;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 GO:1902176| SOD2;GPX1 GO:0006801| superoxide metabolic process SOD1;SOD2 GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;GSR;SOD2 GO:0035722| interleukin-12-mediated signaling pathway SOD1;SOD2 19389:[DB14011 DB03825] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03825|Rhodamine 6G ABCC1 common genes ABCC1 common pathways GO:0055085| transmembrane transport TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;TRPV2 GO:0099133| ABCC1 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 GO:0060326| cell chemotaxis ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0034775| glutathione transmembrane transport ABCC1 19390:[DB14011 DB13876] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13876|Brofaromine MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP2C9;CYP1A1;ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;MAOA;SOD1;CYP3A4 19391:[DB14011 DB04374] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04374|4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole HAO1 common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;HAO1;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2;HAO1 19392:[DB14011 DB09047] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways GO:0048511| rhythmic process AANAT;PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;TOP2A;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 19393:[DB14011 DB01666] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter FST;TRPV4;TRPV1;PPARG GO:0007165| signal transduction OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;CHRNA7;FST;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B 19394:[DB14011 DB04121] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways GO:0050714| positive regulation of protein secretion ARF1;PLA2G1B GO:0043085| positive regulation of catalytic activity SOD1;ARF1 GO:0007015| actin filament organization TRPV4;PLA2G1B;ARF1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;ARF1 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;ARF1;CACNA1G;CACNA1I GO:0097061| dendritic spine organization CHRNA7;ARF1 19395:[DB14011 DB08631] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08631|N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways GO:0032259| methylation CYP1A2;PNMT 19396:[DB14011 DB06249] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06249|Arzoxifene ESR1;ESR2 common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV1;TRPV4 GO:0007165| signal transduction CACNA1I;PLA2G1B;ESR2;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;ESR1;HTR1A;GPR55 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ESR2;PLA2G1B;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2;TRPV4;TRPV1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG;ESR1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TRPV1 19397:[DB14011 DB08564] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08564|(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide SRC common genes common pathways GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;SRC;SOD1 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;SRC;PTGS2;CNR1;SOD1 GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0031667| response to nutrient levels SRC;SOD1 GO:0007165| signal transduction SRC;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption SRC;GPR55 GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0008283| cell proliferation GPX1;SRC;HTR1A;CYP1A1 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;SRC;GPX1;CAT GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT;SRC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0002376| immune system process SRC;IDO1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 19398:[DB14011 DB03526] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03526|AL5927 CA2 common genes common pathways GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1;CA2 GO:0001822| kidney development CA2;CAT 19399:[DB14011 DB04941] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04941|Crofelemer CFTR;ANO1 common genes common pathways GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;ANO1;HTR2A GO:1902476| GLRB;CFTR;GLRA1;ANO1;GLRA3 GO:0071320| cellular response to cAMP CFTR;AANAT GO:0006812| cation transport ANO1;TRPM8 GO:0006811| ion transport TRPA1;GLRA1;CFTR;CACNA1G;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA3;CACNA1H;TRPV3;ANO1;CHRNA7;TRPV2 GO:0006821| chloride transport GLRA1;CFTR;GLRB;GLRA3;ANO1 GO:0099133| CFTR;ABCC1 GO:0006695| cholesterol biosynthetic process CFTR;HMGCR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;ANO1 GO:0050891| multicellular organismal water homeostasis TRPV4;CFTR GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;CHRNA7;ANO1;GLRA3 GO:0055085| transmembrane transport ABCC1;CACNA1G;CFTR;TRPA1;TRPV1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0034605| cellular response to heat PTGS2;ANO1;TRPV4;TRPV1 19400:[DB14011 DB06133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06133|Dimethylcurcumin AR common genes common pathways GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006351| transcription, DNA-dependent AR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;AR GO:0007548| sex differentiation CYP17A1;AR GO:0008283| cell proliferation HTR1A;AR;GPX1;CYP1A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;TRPV4;TRPV1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis CNR1;SOD1;AR 19401:[DB14011 DB07193] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0001666| response to hypoxia CHRNA7;CAT;DPP4;CYP1A1 GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 19402:[DB14011 DB07754] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways GO:0008152| metabolic process SMPD1;FOLH1;ACAT1 19403:[DB14011 DB12379] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12379|Indirubin CYP1A1;AHR common genes CYP1A1 common pathways GO:0017143| insecticide metabolic process CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;PTGS2;CYP1A2 GO:0009636| response to toxin CYP1A1;AHR;CYP1B1;CAT;GPX1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0009624| response to nematode CYP1A1 GO:0043010| camera-type eye development CYP1A1 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:1900087| CYP1A1 GO:0032502| developmental process CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;AHR;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0009692| ethylene metabolic process CYP1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0070988| demethylation CYP1A1 GO:0006351| transcription, DNA-dependent AHR;PPARG GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;AHR GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;PTGS2;CYP1A2 GO:0048511| rhythmic process AHR;PPARG;AANAT GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0006915| apoptotic process AHR;VDAC1;GPX1 GO:0010041| response to iron(III) ion CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0009611| response to wounding GPX1;CYP1A1 GO:0007568| aging CYP1A1;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT GO:0010468| regulation of gene expression AHR;CYP1A2 GO:0009308| amine metabolic process CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0045893| positive regulation of transcription, DNA-dependent AHR;PPARG GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0032094| response to food OPRM1;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent AHR;PPARG GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0055114| oxidation-reduction process CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0009615| response to virus CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;AHR;PPARG GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0009410| response to xenobiotic stimulus GPX1;AHR GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 19404:[DB14011 DB03615] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03615|Ribostamycin P4HB;rpsL common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;P4HB;OPRD1;SLC29A1 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;P4HB;HMGCR GO:0034599| cellular response to oxidative stress GSR;P4HB;SOD1;GPX1;CAT GO:0035722| interleukin-12-mediated signaling pathway P4HB;SOD1 GO:0034976| response to endoplasmic reticulum stress ALOX15;P4HB GO:0045454| cell redox homeostasis P4HB;GPX1;GSR 19405:[DB14011 DB13999] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:1990090| HSPA5;TRPV1 GO:0042953| lipoprotein transport PPARG;LRP1 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;LRP1;CYP2C9;PPARG GO:0009314| response to radiation HSPA5;CAT;OPRM1;PTGS2 GO:0071277| cellular response to calcium ion ALOX15;HSPA5 GO:0007166| cell surface receptor linked signaling pathway ASGR2;F2;TRPV1;TRPA1 GO:0001889| liver development PROC;ACAT1;CYP1A1 GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0010976| positive regulation of neuron projection development HSPA5;CNR1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0071320| cellular response to cAMP HSPA5;AANAT GO:0043524| negative regulation of neuron apoptosis LRP1;SOD1 GO:0061844| PLA2G1B;F2 GO:0034976| response to endoplasmic reticulum stress HSPA5;ALOX15 GO:0001523| retinoid metabolic process NAPEPLD;LRP1 GO:0045740| positive regulation of DNA replication CALR;PLA2G1B GO:0055088| lipid homeostasis PPARG;ASGR2 GO:0008283| cell proliferation LRP1;CYP1A1;HTR1A;GPX1 GO:0007155| cell adhesion CYP1B1;VWF GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;PPARG;TRPV4;TRPV1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;CALR;F2 GO:0002576| platelet degranulation SOD1;VWF GO:0043066| negative regulation of apoptotic process HSPA5;CAT;PROC;GPX1;SOD1;HMGCR;PTGS2 GO:0035722| interleukin-12-mediated signaling pathway CANX;SOD1 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0050728| negative regulation of inflammatory response PROC;CNR2 GO:0055114| oxidation-reduction process CRYZ;PHYH;CYP1A1;CYP2C9;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;CALR;PPARG;CYP1A1;TRPA1 GO:0006631| fatty acid metabolic process ALOX15;PHYH;PTGS1;PTGS2 GO:0051260| protein homooligomerization GLRA3;VWF;ACAT1;GLRA1 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPV4;TRPM8;CALR GO:0010468| regulation of gene expression CYP1A2;F2 GO:0030282| bone mineralization PTGS2;ASGR2;ALOX15 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007568| aging HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT;LRP1;CYP1A1;CANX GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;F2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;CALR GO:0009611| response to wounding CYP1A1;F2;VWF;GPX1 GO:0045892| negative regulation of transcription, DNA-dependent CALR;PPARG GO:0010033| response to organic substance CYP1A1;PPARG;CALR;TRPA1;SOD1;PTGS2;CYP1A2 GO:0007283| spermatogenesis CALR;CNR1;SOD1 GO:0043277| apoptotic cell clearance ALOX15;LRP1 GO:0010977| negative regulation of neuron projection development LRP1;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;CALR GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;HSPA5 19406:[DB14011 DB07326] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07326|6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide KDR common genes common pathways GO:0016032| viral reproduction VDAC1;KDR;HTR2A GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0001525| angiogenesis PTGS2;KDR;CYP1B1 GO:0045766| positive regulation of angiogenesis CHRNA7;KDR;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;KDR;ALOX15 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0043066| negative regulation of apoptotic process KDR;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0008284| positive regulation of cell proliferation KDR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A 19407:[DB14011 DB11598] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11598|Antithrombin III human SERPINC1 common genes common pathways GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0007584| response to nutrient PPARG;SERPINC1;CNR1;HMGCR GO:0007595| lactation SLC29A1;SERPINC1 19408:[DB14011 DB06205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TGFB1;GPX1 GO:0010742| macrophage derived foam cell differentiation PPARG;TGFB1 GO:0071407| cellular response to organic cyclic compound TGFB1;CYP1A1;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent TGFB1;PPARG GO:0042493| response to drug ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;CAT;PTGS2;CYP1A2;TGFB1;SOD1;HTR2A GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2;TGFB1 GO:0035307| positive regulation of protein dephosphorylation TGFB1;SMPD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TGFB1;PPARG;TRPV1;TRPV4 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;ALB GO:0045786| negative regulation of cell cycle PTGS2;TGFB1 GO:0002576| platelet degranulation SOD1;TGFB1;ALB GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;TGFB1;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TGFB1 GO:0030308| negative regulation of cell growth TGFB1;PPARG GO:0042127| regulation of cell proliferation PTGS2;TGFB1;PTGS1 GO:0042060| wound healing ALOX15;TGFB1;OPRM1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2;TGFB1 GO:0045892| negative regulation of transcription, DNA-dependent TGFB1;PPARG GO:0042130| negative regulation of T cell proliferation TGFB1;IDO1 GO:0043406| positive regulation of MAP kinase activity TGFB1;HTR2A GO:0010628| positive regulation of gene expression TGFB1;TRPV4 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;TGFB1 GO:0001657| ureteric bud development CAT;TGFB1 GO:0050714| positive regulation of protein secretion TGFB1;PLA2G1B GO:0006915| apoptotic process VDAC1;TGFB1;GPX1 GO:0060965| negative regulation of gene silencing by miRNA PPARG;TGFB1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;TGFB1;HMGCR;OPRM1;HTR2A;GPR55 GO:0098869| PTGS2;CAT;PTGS1;GPX1;ALB;GSR GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CHRNA7;TGFB1;HTR2A;GPR12 GO:0031100| organ regeneration PPARG;TGFB1 GO:0007568| aging CYP1A1;CAT;TGFB1;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD GO:0010468| regulation of gene expression CYP1A2;TGFB1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;TGFB1 GO:0009611| response to wounding CYP1A1;TGFB1;GPX1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TGFB1;TRPV1 GO:0048565| digestive tract development TGFB1;CYP1A1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TGFB1;HTR2A GO:0051092| positive regulation of NF-kappaB transcription factor activity TGFB1;CAT;PLA2G1B GO:0030217| T cell differentiation GPR18;TGFB1 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;TGFB1;CNR2;PTGS2;ALOX5;PTGS1 GO:0007565| female pregnancy IDO1;TGFB1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;TGFB1 GO:0010629| negative regulation of gene expression OPRD1;TGFB1 GO:0071260| cellular response to mechanical stimulus PTGS2;TGFB1 GO:0007507| heart development TGFB1;PPARG GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;TGFB1;PTGS2;SOD1;CNR1 GO:0009314| response to radiation TGFB1;OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2;TGFB1 GO:0000060| protein import into nucleus, translocation TGFB1;OPRD1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2;TGFB1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;TGFB1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1;TGFB1 GO:0032930| positive regulation of superoxide anion generation TGFB1;SOD1 GO:0048146| positive regulation of fibroblast proliferation TGFB1;PLA2G1B GO:0051781| positive regulation of cell division CAT;TGFB1 GO:0001895| retina homeostasis ALB;SOD1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;TGFB1;ACAT1;AANAT GO:0033280| response to vitamin D PTGS2;TGFB1 GO:0008283| cell proliferation HTR1A;TGFB1;GPX1;CYP1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;TGFB1 GO:0043117| positive regulation of vascular permeability TGFB1;TRPV4 19409:[DB14011 DB11450] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11450|Pimobendan CYP1A2 common genes CYP1A2 common pathways GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0032259| methylation CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1 GO:0045333| cellular respiration CYP1A2 19410:[DB14011 DB01838] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;TRPV2;TTR GO:0043312| neutrophil degranulation ALOX5;TTR;CAT 19411:[DB14011 DB08020] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;ESR1;GPR55;HTR1A;CACNA1I;PLA2G1B;ESR2;SMPD1;GPR18;PPARG GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;ESR1 GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;PLA2G1B;PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR2;TRPV4;TRPV1;ESR1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 19412:[DB14011 DB02236] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;GART GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1;GART 19413:[DB14011 DB01185] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0007283| spermatogenesis SOD1;CNR1;AR GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0001666| response to hypoxia CYP1A1;HSD11B2;CAT;CHRNA7 GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport AR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B2 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1;ESR1;AR GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;HSD11B2;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;AR;PPARG GO:0032094| response to food OPRM1;CYP1A1;HSD11B2 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;HSD11B2;ALOX15;CRYZ;CYP1A1;CYP2C9 GO:0006694| steroid biosynthetic process CYP17A1;HMGCR;PRLR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1;NR3C1;AR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NR3C1;AR;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;PRLR GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;ESR1;AR;PPARG;TRPV1;TRPV4 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;AR GO:0032868| response to insulin stimulus AANAT;CAT;HSD11B2;TRPV4 GO:0007548| sex differentiation AR;CYP17A1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0008285| negative regulation of cell proliferation AR;PTGS2;OPRM1;CYP1B1;PPARG GO:0051384| response to glucocorticoid stimulus PTGS2;HSD11B2 GO:0007566| embryo implantation SOD1;PRLR;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV1;TRPV4 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;AR;CHRNA7;ESR1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;NR3C1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0007565| female pregnancy HSD11B2;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0007595| lactation SLC29A1;PRLR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG GO:0007166| cell surface receptor linked signaling pathway PRLR;TRPA1;TRPV1 GO:0006351| transcription, DNA-dependent NR3C1;ESR1;AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1;NR3C1;AR GO:0050727| regulation of inflammatory response ESR1;PTGS2 19414:[DB14011 DB00606] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways GO:0009725| response to hormone stimulus ACAT1;SFRP4 GO:0006811| ion transport FXYD2;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0008285| negative regulation of cell proliferation SFRP4;PTGS2;OPRM1;CYP1B1;PPARG GO:0098656| SLC22A6;VDAC1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1;SFRP4 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;SFRP4;GPR55;HTR1A GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;FXYD2;TRPV2 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0034220| ion transmembrane transport TRPV1;GLRB;FXYD2;GLRA1;TRPA1;CHRNA7;GLRA3 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;SLC22A6;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPV3;CACNA1H;TRPV2 GO:0010628| positive regulation of gene expression TRPV4;SFRP4 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;SOD1;CYP1A2;PTGS2 GO:0042127| regulation of cell proliferation FXYD2;PTGS2;PTGS1 GO:0001822| kidney development CA2;CAT GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 19415:[DB14011 DB08320] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08320|DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE ESR1;NCOA2 common genes common pathways GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;ESR1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;NCOA2;PPARG;CYP1A1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;HTR2A;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0048511| rhythmic process NCOA2;PPARG;AANAT GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 GO:0032355| response to estradiol stimulus CAT;ESR1;CYP1A2;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TRPV4;TRPV1;ESR1 GO:0007623| circadian rhythm NCOA2;AANAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A 19416:[DB14011 DB01756] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 19417:[DB14011 DB08022] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08022|(2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile PIM1 common genes common pathways GO:0008283| cell proliferation HTR1A;PIM1;GPX1;CYP1A1 GO:0006915| apoptotic process GPX1;PIM1;VDAC1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PIM1;PTGS2;HMGCR 19418:[DB14011 DB07512] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07512|7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE MAOB common genes common pathways GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;MAOB;CYP1A1;IDO1 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;MAOB;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;MAOB;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0022900| electron transport chain MAOB;IDO1;GSR;CYP1A2 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0010269| response to selenium ion GPX1;MAOB GO:0009636| response to toxin GPX1;CAT;MAOB;CYP1A1;CYP1B1 GO:0045471| response to ethanol MAOB;HMGCR;OPRM1;CNR1;SOD1;CAT 19419:[DB14011 DB06926] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes PPARG common pathways GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0030308| negative regulation of cell growth PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0015909| long-chain fatty acid transport PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0048469| cell maturation PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:1905461| PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B 19420:[DB14011 DB00999] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;KCNMA1;SLC12A3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8 GO:0098656| VDAC1;SLC22A6 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT GO:0060083| smooth muscle contraction involved in micturition TRPV1;KCNMA1 GO:0034765| regulation of ion transmembrane transport KCNMA1;CACNA1H;CACNA1I;CACNA1G GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:1902476| SLC12A3;GLRA3;GLRB;GLRA1 GO:0051592| response to calcium ion KCNMA1;AANAT GO:0035725| sodium ion transmembrane transport SLC12A3;CACNA1H;CACNA1I;CACNA1G GO:0006970| response to osmotic stress TRPV4;KCNMA1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;KCNMA1;PTGS2 GO:0055085| transmembrane transport KCNMA1;TRPV3;CACNA1H;SLC12A3;TRPV2;TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;CACNA1I;TRPV4;VDAC1 GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0001666| response to hypoxia CYP1A1;KCNMA1;CHRNA7;CAT GO:0006810| transport TRPV2;SLC12A3;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;KCNMA1;CACNA1H GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0034465| response to carbon monoxide SOD1;KCNMA1 GO:0001822| kidney development CA2;CAT GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 19421:[DB14011 DB06691] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes CYP2D6 common pathways GO:0008542| visual learning HRH1;HMGCR GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS1;ALOX5;CNR2;PTGS2;HRH1 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;NAAA;GPX1;PTGS1;PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A5 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;SLC22A4;CACNA1H;GLRA3;SLC22A5;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0007613| memory CNR1;HTR2A;HRH1;PTGS2;CHRNA7 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;HRH1;OPRD1;CNR2;OPRM1 GO:0006641| triglyceride metabolic process SLC22A4;CAT;GPX1 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1;HTR2A GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0019369| arachidonic acid metabolic process FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;HTR2A GO:0055085| transmembrane transport TRPV2;SLC22A5;SLC22A4;TRPV3;CACNA1H;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G GO:0034220| ion transmembrane transport CHRNA7;SLC22A4;GLRA3;GLRB;TRPV1;GLRA1;TRPA1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CNR1;GPR12;HTR2A;GPR55;HTR1A;HRH1;OPRD1;CNR2;OPRM1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP3A4;CYP1A2 19422:[DB14011 DB07318] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP2C9;CYP1A1;NOS2;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;NOS2;IDO1 GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis NOS2;GSR;GPX1 19423:[DB14011 DB08170] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08170|(1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE MMP7 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;MMP7 GO:0031667| response to nutrient levels SOD1;MMP7 GO:0044849| OPRM1;MMP7 GO:0060135| maternal process involved in female pregnancy MMP7;CNR1 GO:0007568| aging NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT;MMP7;CYP1A1 19424:[DB14011 DB08180] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08180|2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE FNTA;PGGT1B common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;PGGT1B GO:0034097| response to cytokine stimulus PGGT1B;PTGS2;AANAT 19425:[DB14011 DB08087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;AR GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0007548| sex differentiation CYP17A1;AR GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 GO:0008285| negative regulation of cell proliferation AR;PTGS2;OPRM1;CYP1B1;PPARG GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;AR;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV1;TRPV4 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;AR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport TRPV2;AR;CACNA1I;TRPV1;ABCG2;ABCC1 19426:[DB14011 DB00146] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CYP27B1 GO:0008285| negative regulation of cell proliferation VDR;OPRM1;CYP27B1;PTGS2;CYP1B1;PPARG GO:0033280| response to vitamin D CYP27B1;PTGS2;CYP24A1 GO:0007165| signal transduction HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;VDR;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0001649| osteoblast differentiation CAT;CYP24A1 GO:0007595| lactation SLC29A1;VDR GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;TRPV3;CYP27B1;CACNA1H;CHRNA7;VDR;TRPV2 GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR GO:0006351| transcription, DNA-dependent PPARG;VDR GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG GO:0010628| positive regulation of gene expression VDR;TRPV4 GO:0042359| vitamin D metabolic process CYP3A4;CYP27B1;CYP24A1;CYP1A1 GO:0036378| CYP3A4;CYP27B1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;HTR2A;GPR12;VDR;CHRNA7 GO:0046697| decidualization CYP27B1;PTGS2;VDR GO:0030282| bone mineralization PTGS2;CYP27B1;ALOX15 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;VDR GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP27B1;CYP1A2;CAT;CYP24A1;ALOX5;PTGS1;GPX1 GO:0006355| regulation of transcription, DNA-dependent VDR;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;VDR GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP27B1;CYP1A2 GO:0030308| negative regulation of cell growth PPARG;CYP27B1 19427:[DB14011 DB01123] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01123|Proflavine F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;F2;PPARG;GPR18 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 19428:[DB14011 DB06210] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes ABCG2;CYP1A2 common pathways GO:0031100| organ regeneration UGT1A1;PPARG GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A3;UGT1A9;UGT1A1;CYP1A1;CYP2C9;CYP2D6;CYP2C8;CYP2C19 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;UGT1A1;CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP2C8 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0006810| transport TRPV2;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance UGT1A1;TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0002933| CYP2C8;CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLCO1B1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP2C8;CYP1B1;CYP1A1;CYP2C9 GO:0042594| response to starvation PPARG;UGT1A1;ACAT1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;UGT1A1;CYP1A1;IDO1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0033344| cholesterol efflux ABCG2 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0015886| heme transport ABCG2 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;UGT1A1;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C8;CYP2C19;GSR;IDO1;CYP2D6 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP2C8;CYP3A5;CYP2C9 GO:0097267| CYP1B1;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP1A2 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1;UGT1A9 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0007584| response to nutrient UGT1A1;PPARG;HMGCR;CNR1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;UGT1A1;CYP1A1;PPARG;TRPA1 GO:0006811| ion transport TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GLRA3;SLCO1B1;CACNA1H;TRPV3 GO:0045333| cellular respiration CYP1A2 GO:0008283| cell proliferation CYP1A1;MPL;HTR1A;GPX1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0008152| metabolic process UGT1A3;ACAT1;UGT1A9;UGT1A1;SMPD1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2C8;CYP2D6;UGT1A9;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;UGT1A1;CYP2D6;CYP2C19 GO:0001889| liver development UGT1A1;CYP1A1;ACAT1 GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT;UGT1A1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;MPL GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0046415| urate metabolic process ABCG2 19429:[DB14011 DB03065] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03065|7-Nitroindazole-2-Carboxamidine NOS3 common genes common pathways GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 GO:0042311| vasodilation NOS3;GPX1 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0030324| lung development CYP1A2;NOS3 GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;NOS3;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0045454| cell redox homeostasis NOS3;GSR;GPX1 GO:0008285| negative regulation of cell proliferation CYP1B1;NOS3;PPARG;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PPARG;NOS3;SOD1;PTGS2;PTGS1 GO:1902042| GPX1;NOS3 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0045776| negative regulation of blood pressure NOS3;CNR1 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat TRPV1;NOS3;TRPV3;SOD1;TRPV2 19430:[DB14011 DB06421] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways GO:0048511| rhythmic process AANAT;PPARG;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0043065| positive regulation of apoptotic process TOP2A;PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0042752| regulation of circadian rhythm TOP2A;PPARG 19431:[DB14011 DB13133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0007584| response to nutrient HMGCR;CNR1;COL1A1;PPARG GO:0009636| response to toxin CYP1A1;CYP1B1;ADAMTS13;GPX1;CAT GO:0043434| response to peptide hormone stimulus COL1A1;TRPV1 GO:0007601| visual perception CYP1B1;COL1A1;GLRB;CRYZ;GLRA1 GO:0001649| osteoblast differentiation CAT;COL1A1 GO:0031667| response to nutrient levels SOD1;COL1A1 GO:0060351| cartilage development involved in endochondral bone morphogenesis COL1A1;TRPV4 GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;COL1A1;TRPA1 GO:0071260| cellular response to mechanical stimulus PTGS2;COL1A1 GO:0001503| ossification ALOX15;COL1A1 GO:0071356| cellular response to tumor necrosis factor COL1A1;TRPV1;ADAMTS13 GO:0051591| response to cAMP COL1A1;AANAT GO:0034612| response to tumor necrosis factor PTGS2;ADAMTS13 GO:0007605| sensory perception of sound GPX1;SOD1;COL1A1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;COL1A1 GO:0055093| response to hyperoxia CAT;COL1A1;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;COL1A1 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;COL1A1;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;F8;CYP1A1;CYP2C9;CRYZ GO:0071300| cellular response to retinoic acid COL1A1;PPARG GO:0009612| response to mechanical stimulus COL1A1;TRPV4;PPARG GO:0002576| platelet degranulation SOD1;F8 GO:0042060| wound healing OPRM1;ALOX15;COL1A1 GO:0071306| cellular response to vitamin E PPARG;COL1A1 GO:0030199| collagen fibril organization COL1A1;CYP1B1 GO:0071230| cellular response to amino acid stimulus GLRA1;COL1A1 19432:[DB14011 DB07977] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process DHODH;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy DHODH;IDO1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;DHODH;TRPA1;PPARG;CYP1A1 GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;DHODH;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT;DHODH GO:0031000| response to caffeine DHODH;PPARG 19433:[DB14011 DB00233] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes PTGS2;ALOX5 common pathways GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;MPO;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0032094| response to food CYP1A1;OPRM1;MPO GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CHUK GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 GO:0042493| response to drug CHUK;CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG GO:0009750| response to fructose stimulus PTGS2 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0033194| response to hydroperoxide CHUK;GPX1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0036151| PLA2G2E;PLA2G1B GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MPO;CHUK;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0043312| neutrophil degranulation CAT;ALOX5;MPO GO:0045087| innate immune response CHUK;PPARG GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0009612| response to mechanical stimulus TRPV4;PPARG;MPO GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2E GO:0043066| negative regulation of apoptotic process CAT;MPO;GPX1;SOD1;PTGS2;HMGCR GO:0045786| negative regulation of cell cycle PTGS2 GO:0009615| response to virus CHUK;CYP1A1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;PLA2G1B;PPARG GO:0042744| hydrogen peroxide catabolic process CAT;MPO;GPX1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0043200| response to amino acid stimulus CHUK;GLRA3;GLRB GO:0016042| lipid catabolic process PLA2G2E;PLA2G1B;DAGLA;NAPEPLD GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1;CHUK GO:2001300| ALOX5 GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;PLA2G2E GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0071356| cellular response to tumor necrosis factor CHUK;TRPV1 GO:0007568| aging HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;MPO;CAT;CYP1A1 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| PTGS2;HMGCR GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:1902219| PTGS2 GO:0036152| PLA2G1B;PLA2G2E GO:0006979| response to oxidative stress GPX1;MPO;PTGS1;CAT;PTGS2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019430| removal of superoxide radicals MPO;SOD1 GO:0006955| immune response CHUK;OPRD1;CNR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CHUK;CAT GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response IDO1;ALOX15;PLA2G2E;TRPV1;PTGS1;ALOX5;CHUK;CNR2;PTGS2 GO:0019233| sensory perception of pain OPRD1;PTGS2;CNR2;OPRM1;CNR1;HTR2A;TRPV1;TRPA1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0036149| PLA2G2E;PLA2G1B GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;PPARG;CYP2C9;PLA2G2E;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0036148| PLA2G1B;PLA2G2E GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin CYP1B1;CYP1A1;CHUK;GPX1;CAT GO:0033280| response to vitamin D PTGS2 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;CHUK;CAT GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0036150| PLA2G2E;PLA2G1B GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;CHUK GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2E GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A 19434:[DB14011 DB03183] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0002027| regulation of heart rate CACNA1G;PDE4D GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PDE4D;CHRNA7 GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B GO:0007568| aging CAT;HMGCR;PDE4D;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;PDE4D;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18 19435:[DB14011 DB11606] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11606|Susoctocog alfa VWF common genes common pathways GO:0009611| response to wounding CYP1A1;GPX1;VWF GO:0051260| protein homooligomerization GLRA1;GLRA3;VWF;ACAT1 GO:0007155| cell adhesion CYP1B1;VWF GO:0002576| platelet degranulation SOD1;VWF 19436:[DB14011 DB05155] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05155|CR665 OPRK1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;HTR2A;OPRD1;OPRM1 GO:0007626| locomotory behavior OPRK1;OPRM1;SOD1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRB;GLRA1;GLRA3;OPRM1;OPRD1 GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRK1;PPARG;GPR18 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0042220| response to cocaine OPRK1;SMPD1;OPRM1;CNR1 GO:0045471| response to ethanol OPRK1;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0019233| sensory perception of pain TRPA1;OPRK1;TRPV1;HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2 GO:0009314| response to radiation OPRK1;CAT;PTGS2;OPRM1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;VDAC1;GLRB;OPRK1;CACNA1G;GLRA1 GO:0007600| sensory perception TRPV2;OPRM1;OPRK1 GO:0006955| immune response OPRD1;CNR2;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1 GO:0007610| behavior HTR2A;HTR1A;OPRK1 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CACNA1I;PLA2G1B;OPRK1;SMPD1;PPARG;GPR18 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0044849| OPRM1;OPRK1 GO:0032868| response to insulin stimulus TRPV4;OPRK1;CAT;AANAT GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;OPRK1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0043627| response to estrogen stimulus OPRK1;PPARG 19437:[DB14011 DB00585] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00585|Nizatidine HRH2;BCHE;ABCB1 common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0007613| memory CHRNA7;HRH2;HTR2A;CNR1;PTGS2 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH2;HTR2A GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;HRH2;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BCHE;OPRM1;PTGS2 GO:0006955| immune response HRH2;CNR2;OPRD1 GO:0048565| digestive tract development HRH2;CYP1A1 GO:0008542| visual learning HMGCR;HRH2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;GPR12;CNR1;HRH2;OPRM1;CNR2;OPRD1 GO:0006810| transport TRPV2;ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;ABCB1;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HRH2;CNR1;CNR2;OPRM1;OPRD1 GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;BCHE 19438:[DB14011 DB00561] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0007268| synaptic transmission VDAC1;GLRB;KCNK3;CACNA1G;GLRA1;OPRM1;OPRD1;GLRA3;HTR2A GO:0071294| cellular response to zinc ion KCNK3;GLRA1 GO:0006811| ion transport GLRA3;KCNK9;TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;KCNK3;TRPM8;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1 GO:0007420| brain development KCNK3;ACAT1 GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;KCNK3;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;KCNK3 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;TRPV1;GLRB;KCNK3 GO:0071456| cellular response to hypoxia KCNK3;OPRD1;PTGS2;SLC29A1 19439:[DB14011 DB02144] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PITPNA;PTGS2;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1 GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1;PITPNA GO:0035722| interleukin-12-mediated signaling pathway PITPNA;SOD1 19440:[DB14011 DB08026] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08026|2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide MAPK10 common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;MAPK10;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7 GO:0042752| regulation of circadian rhythm PPARG;MAPK10 GO:0009416| response to light stimulus MAPK10;AANAT GO:0048511| rhythmic process PPARG;MAPK10;AANAT GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B;MAPK10 GO:0010468| regulation of gene expression CYP1A2;MAPK10 19441:[DB14011 DB03021] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03021|Ulapualide A ACTA1 common genes common pathways GO:0048741| skeletal muscle fiber development GPX1;ACTA1 GO:0010628| positive regulation of gene expression TRPV4;ACTA1 GO:0006936| muscle contraction GLRA1;CACNA1H;ACTA1 GO:0009612| response to mechanical stimulus ACTA1;TRPV4;PPARG GO:0010226| response to lithium ion ACTA1;PTGS2 19442:[DB14011 DB11455] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11455|Robenacoxib PTGS2 common genes PTGS2 common pathways GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPA1;TRPV1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;ALOX15;IDO1;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;CYP1A1;IDO1 GO:0071284| cellular response to lead ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0009750| response to fructose stimulus PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1A1;CYP2C9;CRYZ;ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:1902219| PTGS2 GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CYP1A1 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 19443:[DB14011 DB07227] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07227|4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE FNTA;FNTB;PGGT1B common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;PGGT1B;HTR2A;PTGS2;HMGCR GO:0034097| response to cytokine stimulus PGGT1B;PTGS2;AANAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;FNTB 19444:[DB14011 DB12598] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12598|Nafamostat F2;F10;F12;PRSS1;KLK1;ICAM1;SLC22A1;SLC22A2 common genes common pathways GO:0071333| cellular response to glucose stimulus ICAM1;SLC29A1 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;IDO1;ICAM1;CYP1A1 GO:0030838| positive regulation of actin filament polymerization ICAM1;ALOX15 GO:0045087| innate immune response PPARG;F12 GO:0007155| cell adhesion ICAM1;CYP1B1 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0007569| cell aging SOD1;ICAM1 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ICAM1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0051926| negative regulation of calcium ion transport ICAM1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;ICAM1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0009235| cobalamin metabolic process PRSS1;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0007605| sensory perception of sound ICAM1;SOD1;GPX1 GO:0051260| protein homooligomerization SLC22A1;GLRA1;GLRA3;ACAT1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;ICAM1 GO:0055085| transmembrane transport SLC22A2;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;ABCC1;SLC22A1;CACNA1G;TRPV2;TRPV3;CACNA1H GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ICAM1;ALOX15;TRPV4 GO:0001541| ovarian follicle development ICAM1;SOD1 GO:0043200| response to amino acid stimulus ICAM1;GLRB;GLRA3 GO:0071356| cellular response to tumor necrosis factor ICAM1;TRPV1 GO:0001666| response to hypoxia ICAM1;CYP1A1;CHRNA7;CAT GO:0046688| response to copper ion ICAM1;AANAT;SOD1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0045471| response to ethanol ICAM1;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0071312| cellular response to alkaloid ICAM1;TRPV1 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ICAM1;HTR2A GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;ICAM1;CAT GO:0016032| viral reproduction ICAM1;VDAC1;HTR2A GO:0046718| entry of virus into host cell HTR2A;ICAM1 GO:0001975| response to amphetamine ICAM1;SOD1;CNR2 GO:0045907| positive regulation of vasoconstriction ICAM1;HTR2A;PTGS2 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ICAM1 GO:0006855| drug transmembrane transport ABCG2;SLC22A2;SLC22A1;ABCC1 GO:0032868| response to insulin stimulus ICAM1;TRPV4;CAT;AANAT GO:0006811| ion transport VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;SLC22A2;TRPM8;CACNA1G;SLC22A1;TRPA1;GLRA1;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ICAM1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0061844| F2;PLA2G1B GO:0006812| cation transport SLC22A2;TRPM8;SLC22A1 GO:1902042| GPX1;ICAM1 19445:[DB14011 DB02955] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02955|Ricinoleic Acid CNR1;CNR2;TRPV1 common genes CNR2;CNR1;TRPV1 common pathways GO:0099553| CNR1 GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0050796| regulation of insulin secretion CNR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0031999| negative regulation of fatty acid beta-oxidation CNR1 GO:0065009| regulation of molecular function TRPV1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;TRPV3;OPRM1;CACNA1H;CHRNA7;TRPV2 GO:0045777| positive regulation of blood pressure CNR1 GO:0006811| ion transport GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1 GO:0032229| negative regulation of synaptic transmission, GABAergic CNR2 GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0051966| regulation of synaptic transmission, glutamatergic CNR1 GO:0038171| GPR55;CNR1;CNR2 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;OPRM1;PTGS2;CNR2;TRPA1;TRPV1 GO:1901594| TRPV1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1 GO:0045776| negative regulation of blood pressure CNR1 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CAT GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0048266| behavioral response to pain TRPV1 GO:0060259| regulation of feeding behavior CNR1 GO:0001774| microglial cell activation TRPV1 GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;PTGS1;NAAA;GPX1 GO:1990090| TRPV1 GO:0071312| cellular response to alkaloid TRPV1 GO:0001659| temperature homeostasis TRPV1;GPX1;HTR2A GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0050955| thermoception TRPA1;TRPV1;TRPM8 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1 GO:0098703| TRPV1 GO:0009268| response to pH TRPV1 GO:0002790| peptide secretion TRPV1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0006955| immune response OPRD1;CNR2 GO:0006816| calcium ion transport CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8;TRPV3;CACNA1H;TRPV2;CHRNA7 GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:0051289| protein homotetramerization TRPM8;TRPV1;CRYZ;TRPA1;CAT GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1 GO:0014047| glutamate secretion TRPV1 GO:0010976| positive regulation of neuron projection development CNR1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0007635| chemosensory behavior TRPV1 GO:0007568| aging CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1 GO:0006810| transport TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0030595| leukocyte chemotaxis CNR2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0071468| cellular response to acidity TRPV1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;TRPA1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0045759| negative regulation of action potential CNR1;CNR2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0042220| response to cocaine SMPD1;OPRM1;CNR1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0051001| negative regulation of nitric-oxide synthase activity CNR1;CNR2 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;GLRA3;CHRNA7 GO:0071502| cellular response to temperature stimulus TRPV1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1 GO:0002866| positive regulation of acute inflammatory response to antigenic stimulus CNR1 GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0007283| spermatogenesis CNR1;SOD1 GO:0001660| fever generation TRPV1 GO:0002024| diet induced thermogenesis TRPV1;TRPV4 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;TRPV1;GLRB GO:0060135| maternal process involved in female pregnancy CNR1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0007611| learning or memory CHRNA7;CNR1 GO:0060405| regulation of penile erection CNR1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;CYP1A1 GO:0043271| negative regulation of ion transport CNR1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG GO:0033602| negative regulation of dopamine secretion CNR1 GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPA1;TRPV1 GO:0007413| axonal fasciculation CNR1 GO:0048265| response to pain TRPA1;TRPV1 GO:0043278| response to morphine OPRM1;CNR1 GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0035094| response to nicotine CNR1;CHRNA7 GO:0050728| negative regulation of inflammatory response CNR2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0033004| negative regulation of mast cell activation CNR1;CNR2 19446:[DB14011 DB02553] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02553|Glutathionylspermidine Disulfide GSR common genes GSR common pathways GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0006749| glutathione metabolic process GPX1;SOD1;GSR GO:0045454| cell redox homeostasis GSR;GPX1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;GSR GO:0098869| GSR;PTGS2;CAT;PTGS1;GPX1 19447:[DB14011 DB08529] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process HMGCR;GGPS1 GO:0008299| isoprenoid biosynthetic process GGPS1;HMGCR GO:0006695| cholesterol biosynthetic process GGPS1;HMGCR 19448:[DB14011 DB01197] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01197|Captopril ACE;MMP2;MMP9;LTA4H;BDKRB1;CYP2D6;ALB;ABCB1;SLC15A1;SLC22A6 common genes CYP2D6 common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG;MMP9 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0001503| ossification ALOX15;MMP9 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP3A4 GO:0051100| negative regulation of binding CYP2D6 GO:0019233| sensory perception of pain HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1;TRPA1;BDKRB1;TRPV1 GO:0001525| angiogenesis CYP1B1;MMP2;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;BDKRB1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;IDO1;BDKRB1 GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5;LTA4H GO:0001934| positive regulation of protein phosphorylation CHRNA7;MMP9 GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0060047| heart contraction SOD1;GPX1;ACE GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;SMPD1;BDKRB1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0007566| embryo implantation PTGS2;SOD1;MMP2;MMP9 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;BDKRB1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;MMP9 GO:0098656| SLC22A6;VDAC1 GO:0008217| regulation of blood pressure PPARG;PTGS1;ACE;PTGS2;SOD1 GO:0006811| ion transport CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1;SLC15A1;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0001895| retina homeostasis ALB;SOD1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0001822| kidney development ACE;CAT GO:0009612| response to mechanical stimulus TRPV4;BDKRB1;PPARG GO:0043066| negative regulation of apoptotic process ALB;MMP9;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0002576| platelet degranulation SOD1;ALB GO:0043312| neutrophil degranulation MMP9;CAT;ALOX5;LTA4H GO:0030308| negative regulation of cell growth PPARG;BDKRB1 GO:0032496| response to lipopolysaccharide IDO1;BDKRB1;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0071230| cellular response to amino acid stimulus GLRA1;MMP2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0006691| leukotriene metabolic process LTA4H;ALOX5;ABCC1;ALOX15 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0043388| positive regulation of DNA binding PPARG;MMP9 GO:0098869| ALB;GSR;CAT;GPX1;PTGS1;PTGS2 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1A1;CYP2C9;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0002446| neutrophil mediated immunity PLA2G1B;ACE GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;BDKRB1 GO:0006810| transport TRPV2;ABCC1;SLC15A1;ABCB1;CACNA1I;TRPV1;ABCG2 GO:0001666| response to hypoxia CYP1A1;MMP2;CHRNA7;CAT GO:0007283| spermatogenesis CNR1;SOD1;ACE GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;VDAC1;ABCB1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1G;SLC22A6;ABCC1;TRPA1;SLC15A1 19449:[DB14011 DB09266] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;MRC1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0046718| entry of virus into host cell HTR2A;MRC1 GO:0016032| viral reproduction HTR2A;MRC1;VDAC1 19450:[DB14011 DB04054] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04054|9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0009409| response to cold TRPA1;PPARG;HSP90AA1;TRPM8 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;HSP90AA1;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HSP90AA1;PTGS2;OPRM1 19451:[DB14011 DB06641] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06641|Perifosine AKT1;MAPK1;PRKCA common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;MAPK1 GO:0071356| cellular response to tumor necrosis factor MAPK1;TRPV1;AKT1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;AKT1;PPARG;CYP1A1;TRPA1 GO:0015758| glucose transport AKT1;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HMGCR;OPRM1;HTR2A;GPR55;TRPV4;ALOX15;PRKCA GO:0006915| apoptotic process GPX1;AKT1;VDAC1;PRKCA;MAPK1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;MAPK1 GO:0045766| positive regulation of angiogenesis CYP1B1;PRKCA;CHRNA7 GO:0042593| glucose homeostasis AKT1;CNR1;TRPV4;PPARG GO:0048538| thymus development SOD1;MAPK1 GO:0006979| response to oxidative stress SOD1;AKT1;PTGS2;CAT;PTGS1;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;AKT1;PTGS2;OPRM1 GO:0071363| cellular response to growth factor stimulus TRPV1;OPRD1;AKT1;CAT GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;GPR55;HTR1A;AKT1;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0071456| cellular response to hypoxia AKT1;OPRD1;PTGS2;SLC29A1 GO:0007568| aging PTGS2;AKT1;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT;CYP1A1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;AKT1;PTGS2 GO:0035094| response to nicotine MAPK1;CNR1;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent PPARG;MAPK1 GO:0032094| response to food CYP1A1;OPRM1;AKT1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;AKT1 GO:0045893| positive regulation of transcription, DNA-dependent AKT1;MAPK1;PPARG GO:1902176| GPX1;AKT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;AKT1 GO:0008284| positive regulation of cell proliferation MAPK1;CHRNA7;HTR2A;HTR1A;AKT1;HMGCR;PTGS2 GO:0043066| negative regulation of apoptotic process AKT1;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0007155| cell adhesion PRKCA;CYP1B1 GO:0043312| neutrophil degranulation ALOX5;CAT;MAPK1 GO:0032496| response to lipopolysaccharide MAPK1;CYP1A1;IDO1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0007611| learning or memory MAPK1;CHRNA7;CNR1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;AKT1;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0045600| positive regulation of fat cell differentiation HTR2A;AKT1;PPARG GO:0071276| cellular response to cadmium ion CYP1A2;AKT1;SOD1;MAPK1 GO:0071380| cellular response to prostaglandin E stimulus AKT1;PPARG GO:0043627| response to estrogen stimulus PPARG;MAPK1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;AKT1 GO:0009636| response to toxin CYP1A1;MAPK1;CYP1B1;CAT;GPX1 GO:0006809| nitric oxide biosynthetic process AKT1;CYP1B1 GO:0014065| phosphatidylinositol 3-kinase cascade AKT1;HTR2A GO:0045907| positive regulation of vasoconstriction AKT1;PTGS2;HTR2A GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;AKT1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;AKT1;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;MAPK1 GO:0009725| response to hormone stimulus ACAT1;AKT1 GO:0031999| negative regulation of fatty acid beta-oxidation AKT1;CNR1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;AKT1 GO:0032287| peripheral nervous system myelin maintenance SOD1;AKT1 GO:0050796| regulation of insulin secretion CNR1;PRKCA GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;AKT1 GO:0001649| osteoblast differentiation CAT;AKT1 GO:0009408| response to heat TRPV2;SOD1;TRPV3;AKT1;TRPV1 GO:0006954| inflammatory response ALOX5;PTGS1;AKT1;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;AKT1 GO:0016032| viral reproduction HTR2A;VDAC1;MAPK1 GO:0010629| negative regulation of gene expression AKT1;OPRD1 GO:0007268| synaptic transmission GLRA1;MAPK1;CACNA1G;GLRB;VDAC1;HTR2A;GLRA3;OPRD1;OPRM1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;AKT1;PTGS2 GO:0001934| positive regulation of protein phosphorylation AKT1;CHRNA7 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;AKT1;PTGS2 GO:0035556| intracellular signal transduction MAPK1;PLA2G1B;PRKCA;AKT1 GO:0007507| heart development MAPK1;PPARG GO:1990090| TRPV1;AKT1 GO:0007399| nervous system development SMPD1;GLRB;AKT1 GO:0071260| cellular response to mechanical stimulus AKT1;PTGS2 GO:0001525| angiogenesis CYP1B1;PRKCA;PTGS2 GO:0000060| protein import into nucleus, translocation AKT1;OPRD1 GO:0019233| sensory perception of pain MAPK1;TRPA1;TRPV1;OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1 GO:0006351| transcription, DNA-dependent PPARG;MAPK1 19452:[DB14011 DB02011] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;OTC;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0070207| protein homotrimerization TRPM8;OTC GO:0031667| response to nutrient levels OTC;SOD1 GO:0001889| liver development CYP1A1;OTC;ACAT1 GO:0032868| response to insulin stimulus CAT;OTC;AANAT;TRPV4 GO:0010043| response to zinc ion OTC;AANAT 19453:[DB14011 DB04709] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006351| transcription, DNA-dependent PPARG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;AR;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0008283| cell proliferation HTR1A;GPX1;AR;CYP1A1 GO:0007548| sex differentiation CYP17A1;AR GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;AR 19454:[DB14011 DB01612] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;NPR1 GO:0008217| regulation of blood pressure PPARG;NPR1;PTGS1;PTGS2;SOD1 GO:0035556| intracellular signal transduction NPR1;PLA2G1B GO:0008152| metabolic process SMPD1;ALDH2;ACAT1 GO:0007166| cell surface receptor linked signaling pathway NPR1;TRPV1;TRPA1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;NPR1;GPR18;PPARG GO:0030308| negative regulation of cell growth NPR1;PPARG GO:0016525| negative regulation of angiogenesis PPARG;NPR1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP2C9;CYP1A1;CRYZ;ALOX5;PTGS1;GPX1;CAT;CYP3A7;PTGS2;ALDH2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0022900| electron transport chain CYP1A2;ALDH2;GSR;IDO1 19455:[DB14011 DB08152] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08152|{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate F2 common genes common pathways GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;GPR18;PPARG;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 19456:[DB14011 DB01777] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes AANAT common pathways GO:0007623| circadian rhythm AANAT GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0009648| photoperiodism AANAT GO:0006474| N-terminal protein amino acid acetylation AANAT GO:0034695| response to prostaglandin E stimulus AANAT GO:0030187| melatonin biosynthetic process AANAT GO:0051591| response to cAMP AANAT GO:0046688| response to copper ion AANAT;SOD1 GO:0048511| rhythmic process AANAT;PPARG GO:0009416| response to light stimulus AANAT GO:0051592| response to calcium ion AANAT GO:0071320| cellular response to cAMP AANAT GO:0046219| indolalkylamine biosynthetic process AANAT GO:0051412| response to corticosterone stimulus AANAT GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT GO:0010043| response to zinc ion AANAT 19457:[DB14011 DB09220] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09220|Nicorandil ABCC9 common genes common pathways GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;ABCC9;SMPD1 GO:0065009| regulation of molecular function TRPV1;ABCC9 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;ABCC9;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCC9;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0099133| ABCC9;ABCC1 19458:[DB14011 DB14518] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0019731| antibacterial humoral response APP;PLA2G1B GO:0050808| synapse organization CHRNA7;APP GO:0042493| response to drug CAT;HTR2A;SOD1;ATP1A1;PTGS2;CYP1A2;ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:1905906| CHRNA7;APP GO:0007611| learning or memory APP;CHRNA7;CNR1 GO:0007612| learning APP;VDAC1;PTGS2 GO:0008203| cholesterol metabolic process APP;CAT;HMGCR GO:0010288| response to lead ion APP;CAT GO:0045087| innate immune response PPARG;APP GO:0007155| cell adhesion APP;CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;APP;PPARG GO:0043066| negative regulation of apoptotic process ALB;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0002576| platelet degranulation TF;SOD1;ALB;APP GO:0007626| locomotory behavior OPRM1;SOD1;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;PPARG;PLA2G1B GO:0006915| apoptotic process GPX1;APP;VDAC1 GO:0000187| activation of MAPK activity APP;PLA2G1B;SOD1;CHRNA7 GO:0086002| ATP1A1;CACNA1G GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HMGCR;OPRM1;HTR2A;GPR55;TRPV4;ALOX15;APP GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;CHRNA7;ATP1A1;GLRA3 GO:0051262| protein tetramerization APP;HMGCR;CAT GO:2000463| positive regulation of excitatory postsynaptic membrane potential APP;CHRNA7 GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0010468| regulation of gene expression CYP1A2;APP GO:0098815| CHRNA7;APP GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;APP;PPARG;GPR18 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2;APP GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TRPV1;OPRM1;PTGS2 GO:0051260| protein homooligomerization APP;GLRA1;GLRA3;ACAT1 GO:0001934| positive regulation of protein phosphorylation APP;CHRNA7 GO:1902004| CHRNA7;APP GO:0010629| negative regulation of gene expression OPRD1;APP GO:0007268| synaptic transmission APP;CACNA1G;GLRA1;VDAC1;GLRB;OPRD1;OPRM1;HTR2A;GLRA3 GO:0071320| cellular response to cAMP AANAT;APP GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;TF GO:0008542| visual learning APP;HMGCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;PLA2G1B;CAT GO:0001774| microglial cell activation TRPV1;APP GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:1990090| APP;TRPV1 GO:0007399| nervous system development GLRB;SMPD1;APP GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;APP;SMPD1;CNR1;SOD1;PTGS2 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0001895| retina homeostasis SOD1;TF;ALB GO:0008344| adult locomotory behavior APP;OPRD1 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;ATP1A1;CACNA1H;TF;TRPV3;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPA1;GLRA1;CACNA1G GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;APP;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS2;ATP1A1;SOD1;PTGS1 GO:0032930| positive regulation of superoxide anion generation APP;SOD1 GO:0061844| PLA2G1B;APP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRD1;OPRM1 GO:0007613| memory APP;CHRNA7;PTGS2;CNR1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;APP;OPRM1;HTR2A GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP GO:1900273| APP;CHRNA7 19459:[DB14011 DB07921] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07921|2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide MMP12 common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;MMP12 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MMP12 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;TRPV1;TRPV4;PPARG GO:0042060| wound healing ALOX15;MMP12;OPRM1 19460:[DB14011 DB07684] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways GO:0001666| response to hypoxia PLAT;CYP1A1;CAT;CHRNA7 19461:[DB14011 DB07300] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PDPK1 GO:0035556| intracellular signal transduction PLA2G1B;PDPK1 GO:0006351| transcription, DNA-dependent PDPK1;PPARG GO:0043524| negative regulation of neuron apoptosis SOD1;PDPK1 GO:0045766| positive regulation of angiogenesis CHRNA7;PDPK1;CYP1B1 GO:0006355| regulation of transcription, DNA-dependent PDPK1;PPARG 19462:[DB14011 DB12733] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12733|Dipraglurant GRM5 common genes common pathways GO:0051966| regulation of synaptic transmission, glutamatergic GRM5;CNR1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;GRM5;OPRD1;CNR2;OPRM1 GO:0050890| cognition CHRNA7;GRM5 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;GRM5;OPRM1;GLRB;VDAC1;GLRA1;CACNA1G GO:0060078| regulation of postsynaptic membrane potential GRM5;CHRNA7 GO:0007216| metabotropic glutamate receptor signaling pathway DAGLA;GRM5 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;CNR1;GPR12;GPR55;HTR1A;GRM5;OPRD1;OPRM1;CNR2 GO:0050808| synapse organization CHRNA7;GRM5 GO:0007626| locomotory behavior OPRM1;GRM5;SOD1 GO:0007612| learning GRM5;PTGS2;VDAC1 GO:0007611| learning or memory CHRNA7;GRM5;CNR1 19463:[DB14011 DB02735] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways GO:0007565| female pregnancy IDO1;STS GO:0008152| metabolic process STS;ACAT1;SMPD1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2;STS GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;STS;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;STS;HMGCR;CYP3A4 GO:0006687| glycosphingolipid metabolic process SMPD1;STS 19464:[DB14011 DB02507] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes CYP2C9 common pathways GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;NAAA;GPX1;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0043603| cellular amide metabolic process CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0019627| urea metabolic process CYP2C9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALOX5;PTGS1;GPX1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 19465:[DB14011 DB03280] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03280|P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate DTYMK;tmk;tmk common genes common pathways GO:0043627| response to estrogen stimulus PPARG;DTYMK GO:0008283| cell proliferation DTYMK;CYP1A1;GPX1;HTR1A GO:0015949| nucleobase-containing small molecule interconversion GSR;DTYMK GO:0045445| myoblast differentiation HMGCR;DTYMK GO:0046686| response to cadmium ion DTYMK;CAT GO:0071363| cellular response to growth factor stimulus DTYMK;TRPV1;OPRD1;CAT 19466:[DB14011 DB03169] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03169|(S)-Hmg-Coa HMGCR common genes HMGCR common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0008203| cholesterol metabolic process CAT;HMGCR GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR GO:0006695| cholesterol biosynthetic process HMGCR GO:0006694| steroid biosynthetic process CYP17A1;HMGCR GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010666| positive regulation of cardiac muscle cell apoptosis HMGCR GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0097756| PTGS2;HMGCR GO:0007568| aging CYP1A1;CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1 GO:0051262| protein tetramerization CAT;HMGCR GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0045540| regulation of cholesterol biosynthetic process HMGCR GO:0008299| isoprenoid biosynthetic process HMGCR GO:0016126| sterol biosynthetic process HMGCR GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0061045| negative regulation of wound healing HMGCR GO:0045471| response to ethanol CAT;OPRM1;HMGCR;SOD1;CNR1 GO:0008542| visual learning HMGCR GO:0045445| myoblast differentiation HMGCR GO:0015936| coenzyme A metabolic process ACAT1;HMGCR GO:0006743| ubiquinone metabolic process HMGCR GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0048643| positive regulation of skeletal muscle tissue development HMGCR GO:0010664| negative regulation of striated muscle cell apoptosis HMGCR 19467:[DB14011 DB01586] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCG2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;ABCC4;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;NR1H4;CAT GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;SLC10A2;SLC10A1;GLRA3;CACNA1H;TRPV3;SLCO1A2;CHRNA7;TRPV2 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;NR1H4;CHRNA7 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0046718| entry of virus into host cell SLC10A1;HTR2A GO:0016032| viral reproduction VDAC1;SLC10A1;HTR2A GO:0042448| progesterone metabolic process AKR1C2;CYP17A1 GO:0006954| inflammatory response ALOX5;PTGS1;NR1H4;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1;ABCC2 GO:0007565| female pregnancy IDO1;ABCC2 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;DAGLA;CYP2D6;AKR1C2;ALOX15;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;GPX1;PTGS1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2;AKR1C2 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0006351| transcription, DNA-dependent NR1H4;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1H4 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;ABCB11;CACNA1H GO:0045471| response to ethanol CAT;CYP2E1;SOD1;CNR1;OPRM1;HMGCR GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0006357| regulation of transcription from RNA polymerase II promoter NR1H4;PPARG GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP1A1;CYP2D6;CYP2C19 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;ABCC4;TRPA1;PPARG;CYP1A1 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0010193| response to ozone CYP2E1;CAT GO:0007043| cell-cell junction assembly NR1H4;TRPV4 GO:0030855| epithelial cell differentiation PPARG;VDAC1;AKR1C2 GO:0055085| transmembrane transport TRPV2;ABCC4;CACNA1H;TRPV3;SLCO1A2;ABCB11;TRPV1;CACNA1I;TRPV4;VDAC1;SLC10A2;SLC10A1;ABCG2;ABCC2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0006979| response to oxidative stress ABCC2;SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0032720| negative regulation of tumor necrosis factor production NR1H4;CHRNA7;GPR18 GO:0002376| immune system process IDO1;NR1H4 GO:0042593| glucose homeostasis TRPV4;PPARG;NR1H4;CNR1 GO:0006810| transport TRPV2;ABCB11;CACNA1I;TRPV1;SLC10A1;SLC10A2;ABCG2;ABCC2;ABCC1 GO:0008202| steroid metabolic process CYP2C19;AKR1C2;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;AKR1C2;PPARG;GPR18 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C2;GPX1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1H4 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;ABCC4 GO:0010243| response to organic nitrogen ABCC4;PTGS2;CYP2E1;TRPV1 GO:0050728| negative regulation of inflammatory response CNR2;NR1H4 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;ABCC4;CYP2E1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;AKR1C2;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0099133| ABCC4;ABCC1;ABCC2 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1H4 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0042493| response to drug CYP1A2;PTGS2;CYP2E1;HTR2A;SOD1;ABCC4;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;ABCC2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;NR1H4 GO:0045087| innate immune response PPARG;NR1H4 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;NR1H4;SOD1;GPX1;CAT GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP2E1;CYP1A2 GO:0008284| positive regulation of cell proliferation AKR1C2;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;PPARG;PLA2G1B GO:0002576| platelet degranulation SOD1;ABCC4 GO:0032496| response to lipopolysaccharide CYP1A1;ABCC2;IDO1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 19468:[DB14011 DB00880] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways GO:1902476| GLRA3;SLC12A3;GLRA1;GLRB GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;SLC12A3 GO:0006811| ion transport TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;CACNA1G;GLRA1;TRPA1;SLC12A3;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0098656| SLC22A6;VDAC1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 GO:0001822| kidney development CAT;CA2 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;SLC12A3;SLC22A6;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8 GO:0010033| response to organic substance CA2;CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;SLC12A3;TRPV2 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 19469:[DB14011 DB04563] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04563|CRA_9678 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19470:[DB14011 DB05495] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05495|PG-530742 MMP9 common genes common pathways GO:0007566| embryo implantation PTGS2;SOD1;MMP9 GO:0071276| cellular response to cadmium ion MMP9;SOD1;CYP1A2 GO:0043065| positive regulation of apoptotic process MMP9;PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0001503| ossification ALOX15;MMP9 GO:0001934| positive regulation of protein phosphorylation CHRNA7;MMP9 GO:0043388| positive regulation of DNA binding PPARG;MMP9 GO:0043066| negative regulation of apoptotic process MMP9;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT;MMP9 19471:[DB14011 DB11113] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways GO:0006955| immune response PTGER4;OPRD1;CNR2 GO:0031622| positive regulation of fever generation CNR1;PTGER3;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;PTGER4 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;PTGER4 GO:0071380| cellular response to prostaglandin E stimulus PPARG;PTGER4 GO:0050729| positive regulation of inflammatory response PTGER4;TRPV4 GO:0007165| signal transduction PTGER3;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;SMPD1;PTGER4;GPR18;PPARG;PLA2G1B;CACNA1I GO:0050728| negative regulation of inflammatory response CNR2;PTGER4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;PTGER3;OPRD1;OPRM1 GO:0032496| response to lipopolysaccharide CYP1A1;PTGER4;IDO1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0009612| response to mechanical stimulus TRPV4;PPARG;PTGER4 GO:0008219| cell death PTGER3;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;PTGER3;HTR1A;GPR55;GPR12;CNR1;HTR2A;PTGER4;PPARG;GPR18 19472:[DB14011 DB12339] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12339|Radezolid RRBP1;NIP7 common genes common pathways GO:0001649| osteoblast differentiation RRBP1;CAT 19473:[DB14011 DB11085] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11085|Resorcinol TPO common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP1A1;CYP2C9;TPO;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0098869| GSR;TPO;CAT;PTGS1;GPX1;PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;TPO GO:0042446| hormone biosynthetic process TPO;CYP17A1 GO:0042744| hydrogen peroxide catabolic process TPO;CAT;GPX1 19474:[DB14011 DB07932] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07932|dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate ESR1;NCOA2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;ESR1;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0019216| regulation of lipid metabolic process NCOA2;PPARG;CYP1A1;HMGCR;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1;TRPV1;TRPV4 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;PPARG;NCOA2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;TRPV1;TRPV4;ESR1 GO:0007623| circadian rhythm NCOA2;AANAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0048511| rhythmic process AANAT;NCOA2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT 19475:[DB14011 DB13772] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13772|Rufloxacin CYP1A2 common genes CYP1A2 common pathways GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;CYP1A1;PPARG GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 19476:[DB14011 DB02159] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02159|(R)-Propylene glycol icd;LYZ common genes common pathways GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B GO:0043312| neutrophil degranulation ALOX5;CAT;LYZ GO:0001895| retina homeostasis LYZ;SOD1 GO:0006954| inflammatory response TRPV1;LYZ;ALOX15;IDO1;PTGS1;ALOX5;CNR2;PTGS2 GO:0008152| metabolic process ACAT1;SMPD1;LYZ 19477:[DB14011 DB03866] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03866|Prostaglandin G2 PTGS2 common genes PTGS2 common pathways GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;AANAT;ACAT1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;IDO1;CYP1A1 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0007568| aging HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:1902219| PTGS2 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 19478:[DB14011 DB01926] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01926|Carboxymycobactin S LCN2 common genes common pathways GO:0006879| cellular iron ion homeostasis SOD1;LCN2;ABCG2 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;LCN2;CHRNA7 GO:0043312| neutrophil degranulation LCN2;ALOX5;CAT GO:0045087| innate immune response PPARG;LCN2 GO:0006915| apoptotic process LCN2;GPX1;VDAC1 GO:0002376| immune system process IDO1;LCN2 19479:[DB14011 DB02741] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02741|CD564 RARG common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;RARG GO:0008284| positive regulation of cell proliferation CHRNA7;RARG;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0043066| negative regulation of apoptotic process GPX1;RARG;CAT;HMGCR;PTGS2;SOD1 GO:0032526| response to retinoic acid RARG;PPARG GO:0010628| positive regulation of gene expression RARG;TRPV4 GO:0010468| regulation of gene expression CYP1A2;RARG GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;RARG;PTGS2;OPRM1 GO:0043010| camera-type eye development RARG;CYP1A1 19480:[DB14011 DB04798] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04798|THIO-ATPA GRIA2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;GLRA3;OPRM1;CHRNA7;GRIA2;SLC29A1 GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;TRPV1;GLRA3;CHRNA7;GRIA2 GO:0007268| synaptic transmission CACNA1G;GLRA1;GLRB;VDAC1;OPRD1;OPRM1;GLRA3;HTR2A;GRIA2 GO:0007165| signal transduction GRIA2;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006811| ion transport TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GRIA2;GLRA3;TRPV3;CACNA1H 19481:[DB14011 DB07215] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07215|2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID NCOA1;PPARA common genes common pathways GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0007507| heart development PPARA;PPARG GO:0006629| lipid metabolic process PPARA;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1;PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;NCOA1;PTGS2 GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0006351| transcription, DNA-dependent PPARG;PPARA;NCOA1 GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0032868| response to insulin stimulus CAT;AANAT;PPARA;TRPV4 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA1 GO:0019216| regulation of lipid metabolic process PPARA;NCOA1;CNR1;HMGCR;CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;NCOA1;PPARG GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PPARA;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent NCOA1;PPARA;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA1;PPARA;PPARG;PLA2G1B GO:0042060| wound healing ALOX15;OPRM1;PPARA GO:0048511| rhythmic process PPARG;PPARA;AANAT GO:0001666| response to hypoxia CYP1A1;PPARA;CHRNA7;CAT GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0010468| regulation of gene expression PPARA;CYP1A2 19482:[DB14011 DB03085] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03085|Glycolic acid G6PD;thiO common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG;G6PD GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;G6PD GO:0006749| glutathione metabolic process SOD1;GPX1;G6PD;GSR GO:0045471| response to ethanol G6PD;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0006629| lipid metabolic process TRPV1;PLA2G1B;G6PD;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;GPX1;NAAA;PTGS1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0010041| response to iron(III) ion CYP1A1;G6PD GO:0032094| response to food OPRM1;CYP1A1;G6PD GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;G6PD;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0043523| regulation of neuron apoptosis G6PD;GPX1 GO:0006695| cholesterol biosynthetic process G6PD;HMGCR GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;G6PD;GSR 19483:[DB14011 DB12579] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12579|JNJ-37822681 DRD2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;DRD2;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0007626| locomotory behavior SOD1;OPRM1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;DRD2 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0007628| adult walking behavior GLRA1;DRD2;GLRB GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;DRD2;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0035094| response to nicotine CNR1;CHRNA7;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0043278| response to morphine DRD2;CNR1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;DRD2;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0051209| release of sequestered calcium ion into cytosol DRD2;TRPV1;TRPA1;HTR2A GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;TRPM8;TRPV4;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;DRD2;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0042220| response to cocaine SMPD1;DRD2;OPRM1;CNR1 GO:0001666| response to hypoxia DRD2;CYP1A1;CHRNA7;CAT GO:0009416| response to light stimulus DRD2;AANAT GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;DRD2 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0045776| negative regulation of blood pressure CNR1;DRD2 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CAT;DRD2 GO:0048678| response to axon injury SOD1;DRD2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0001659| temperature homeostasis TRPV1;DRD2;GPX1;HTR2A GO:0048148| behavioral response to cocaine DRD2;HTR2A GO:0035556| intracellular signal transduction PLA2G1B;DRD2 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0001964| startle response GLRB;DRD2;GLRA1 GO:0008542| visual learning DRD2;HMGCR GO:0001975| response to amphetamine SOD1;CNR2;DRD2 GO:0050482| arachidonic acid secretion PLA2G1B;DRD2 GO:1900273| CHRNA7;DRD2 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;DRD2;CACNA1I;GPR18;PPARG;SMPD1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;DRD2;CYP1B1 GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0014854| response to inactivity CAT;DRD2 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;DRD2;CYP1B1 19484:[DB14011 DB03773] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;SLC16A1 GO:0032094| response to food OPRM1;SLC16A1;CYP1A1 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2;TRPV3;CACNA1H;SLC16A7;TRPV2;SLC16A1 GO:0042593| glucose homeostasis SLC16A1;CNR1;TRPV4;PPARG GO:0008152| metabolic process AMY2A;ACAT1;SMPD1 GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;SLC16A1;NAAA;GPX1;PTGS1 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 19485:[DB14011 DB07460] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways GO:0045087| innate immune response PTK2;PPARG GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;PTK2 GO:0043066| negative regulation of apoptotic process PTK2;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0043542| endothelial cell migration CYP1B1;PTK2 GO:0042127| regulation of cell proliferation PTK2;PTGS2;PTGS1 GO:0051897| positive regulation of protein kinase B signaling cascade PTK2;GPX1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PTK2;CAT GO:0001525| angiogenesis PTK2;CYP1B1;PTGS2 GO:0043087| regulation of GTPase activity PTK2;SOD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;PTK2 GO:0001890| placenta development SOD1;PPARG;PTK2 19486:[DB14011 DB04564] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04564|Gluconolactone LCT common genes common pathways GO:0008152| metabolic process SMPD1;LCT;ACAT1 19487:[DB14011 DB05116] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05116|Thymectacin TYMS common genes common pathways GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT;TYMS;CYP1A1 GO:0033189| response to vitamin A CAT;PPARG;TYMS;CYP1A1 GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;ABCC1;TYMS;CYP1A1;PPARG;TRPA1;ABCG2 GO:0034097| response to cytokine stimulus AANAT;PTGS2;TYMS GO:0032259| methylation TYMS;CYP1A2 GO:0007623| circadian rhythm TYMS;AANAT GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS GO:0009636| response to toxin CYP1A1;TYMS;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TRPA1;TYMS;CYP1A1;PPARG GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0045471| response to ethanol TYMS;OPRM1;HMGCR;SOD1;CNR1;CAT 19488:[DB14011 DB00411] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0007517| muscle organ development CACNA1H;ACHE GO:0035094| response to nicotine CNR1;CHRNA2;CHRNA7 GO:0019369| arachidonic acid metabolic process FAAH;PLA2G4A;CYP2D6;DAGLA;ALOX15;CYP1B1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;CHRNA2;SLC29A1;CHRNA7;GLRA1;GLRB;TRPV1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLA2G4A GO:0036151| PLA2G1B;PLA2G4A GO:0007155| cell adhesion ACHE;CYP1B1 GO:0009615| response to virus CYP1A1;CHRM2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;CHRM1;HTR2A;PTGS2;HMGCR GO:0006654| phosphatidic acid biosynthetic process PLA2G4A;PLA2G1B GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0034220| ion transmembrane transport CHRNA7;CHRNA2;GLRA3;GLRB;TRPV1;GLRA1;TRPA1 GO:0016042| lipid catabolic process NAPEPLD;PLA2G4A;DAGLA;PLA2G1B GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;CNR1;CNR2;OPRM1;OPRD1 GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;PLA2G4A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;CHRM2;HTR1A;GPR55;CHRM1;CHRM3;GPR18;PPARG;CHRM4 GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0036152| PLA2G4A;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway CHRM4;TRPV1;TRPA1 GO:0036149| PLA2G4A;PLA2G1B GO:0008016| regulation of heart contraction CHRM2;CACNA1H GO:0036148| PLA2G4A;PLA2G1B GO:0007399| nervous system development GLRB;SMPD1;CHRM3;ACHE;CHRM1;CHRM2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG;PLA2G4A GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CHRNA2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CHRM2 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0008152| metabolic process ACAT1;PLA2G4A;SMPD1 GO:0008283| cell proliferation CHRM4;CYP1A1;CHRM3;GPX1;CHRM1;HTR1A;ACHE GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8;TRPV3;CACNA1H;GLRA3;CHRNA2;TRPV2;CHRNA7 GO:0009395| phospholipid catabolic process NAPEPLD;PLA2G4A GO:0036150| PLA2G4A;PLA2G1B GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0051291| protein heterooligomerization GLRA1;GLRB;CHRNA2 GO:0050890| cognition CHRM1;CHRNA7 GO:0007165| signal transduction CHRNA7;CHRNA2;CHRM1;GPR55;HTR1A;CHRM2;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;CHRM4;PPARG;GPR18;CHRM3;SMPD1 GO:0006939| smooth muscle contraction CHRM3;HTR2A GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G4A 19489:[DB14011 DB04860] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04860|Isatoribine TLR7 common genes common pathways GO:0045087| innate immune response TLR7;PPARG GO:0002376| immune system process TLR7;IDO1 GO:0071260| cellular response to mechanical stimulus TLR7;PTGS2 GO:0001774| microglial cell activation TLR7;TRPV1 GO:0006955| immune response TLR7;OPRD1;CNR2 GO:0006954| inflammatory response TLR7;IDO1;ALOX15;TRPV1;PTGS2;CNR2;ALOX5;PTGS1 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;TLR7;SMPD1;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0050729| positive regulation of inflammatory response TRPV4;TLR7 19490:[DB14011 DB00291] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00291|Chlorambucil GSTP1;SLCO1A2 common genes common pathways GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;GSTP1 GO:0098869| CAT;GPX1;PTGS1;PTGS2;GSR;GSTP1 GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production GPR18;GSTP1;CHRNA7 GO:0055085| transmembrane transport TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLCO1A2 GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0034599| cellular response to oxidative stress GSR;GSTP1;SOD1;CAT;GPX1 GO:0000302| response to reactive oxygen species GPX1;CAT;SOD1;GSTP1 GO:0043312| neutrophil degranulation ALOX5;CAT;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0032869| cellular response to insulin stimulus PLA2G1B;GSTP1;PPARG GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0009636| response to toxin CYP1A1;GSTP1;CYP1B1;CAT;GPX1 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1H;SLCO1A2;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0006749| glutathione metabolic process GSR;GSTP1;GPX1;SOD1 GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;GSTP1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;GSTP1;CYP2C9 GO:0008152| metabolic process GSTP1;SMPD1;ACAT1 GO:0031667| response to nutrient levels GSTP1;SOD1 GO:1904706| PPARG;GSTP1 19491:[DB14011 DB08228] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;NQO2 GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;NQO2;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;NQO2 19492:[DB14011 DB05046] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05046|V1003 OPRK1;OPRM1 common genes OPRM1 common pathways GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;OPRK1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0042060| wound healing ALOX15;OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRB;GLRA1;GLRA3;OPRD1;OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:0032094| response to food OPRM1;CYP1A1 GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0032100| positive regulation of appetite OPRM1 GO:0038003| opioid receptor signaling pathway OPRM1;OPRD1;OPRK1 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;GPR18;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0042220| response to cocaine OPRK1;SMPD1;CNR1;OPRM1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0050769| positive regulation of neurogenesis OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPV1;OPRK1;TRPA1 GO:0045471| response to ethanol OPRK1;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0009314| response to radiation OPRK1;PTGS2;OPRM1;CAT GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;GLRA1;CACNA1G;OPRK1;GLRB;VDAC1 GO:0007600| sensory perception OPRM1;TRPV2;OPRK1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0006955| immune response CNR2;OPRD1;OPRK1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4 GO:0071315| cellular response to morphine OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0007165| signal transduction GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;OPRK1;PLA2G1B;CACNA1I GO:0007610| behavior HTR1A;HTR2A;OPRK1 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;TRPV3;CACNA1H;OPRM1;CHRNA7;TRPV2 GO:0044849| OPRM1;OPRK1 GO:0032868| response to insulin stimulus TRPV4;OPRK1;AANAT;CAT GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 19493:[DB14011 DB06871] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06871|17-METHYL-17-ALPHA-DIHYDROEQUILENIN ESR1;NCOA2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;HTR1A;GPR55;ESR1;OPRD1;OPRM1;CNR2;CHRNA7 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;NCOA2;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;NCOA2;PPARG;ESR1 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0048511| rhythmic process AANAT;PPARG;NCOA2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT 19494:[DB14011 DB06901] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 19495:[DB14011 DB07691] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways GO:0006351| transcription, DNA-dependent PPARD;PPARG GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;PPARD;NAAA;GPX1;PTGS1 GO:0007507| heart development PPARG;PPARD GO:0007566| embryo implantation SOD1;PTGS2;PPARD GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0008283| cell proliferation HTR1A;PPARD;GPX1;CYP1A1 GO:0014823| response to activity CAT;PPARD GO:0001890| placenta development SOD1;PPARD;PPARG GO:0060612| adipose tissue development ACAT1;PPARD GO:0019395| fatty acid oxidation PPARG;PPARD GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;PPARD GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0042127| regulation of cell proliferation PPARD;PTGS2;PTGS1 GO:0042060| wound healing ALOX15;PPARD;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;PPARD GO:0043066| negative regulation of apoptotic process SOD1;PPARD;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PPARD;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARD GO:0033189| response to vitamin A CAT;PPARD;CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0050728| negative regulation of inflammatory response PPARD;CNR2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0046697| decidualization PPARD;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1;PPARD GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0006915| apoptotic process GPX1;PPARD;VDAC1 GO:0015758| glucose transport PPARD;PLA2G1B GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0010033| response to organic substance SOD1;PPARD;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0010628| positive regulation of gene expression TRPV4;PPARD 19496:[DB14011 DB01214] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes CYP2D6 common pathways GO:0045453| bone resorption ADRB2;GPR55 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0007165| signal transduction PLA2G1B;CACNA1I;ADRB1;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;ADRB2;HTR1A;GPR55 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0001659| temperature homeostasis ADRB1;TRPV1;HTR2A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB2;CNR1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0009409| response to cold ADRB1;TRPM8;TRPA1;PPARG;ADRB2 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ADRB2 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0051100| negative regulation of binding CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;ADRB2;ADRB1;PPARG;GPR18 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1A1;CYP2C9 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PLA2G1B;PPARG GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1;ADRB2 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0019369| arachidonic acid metabolic process CYP2D6;DAGLA;ALOX15;CYP1B1;FAAH GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT 19497:[DB14011 DB00044] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00044|Lutropin alfa LHCGR common genes common pathways GO:0050890| cognition CHRNA7;LHCGR GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;LHCGR;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;LHCGR GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;LHCGR;HTR1A;GPR55;GPR18;PPARG GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger LHCGR;CNR1;OPRM1;CNR2;OPRD1 19498:[DB14011 DB08808] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes CYP2D6 common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;ADRB2;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18;ADRB3;ADRB1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0007568| aging NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT;CYP1A1;ADRB3 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;CNR2;OPRM1;ADRB3 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0002024| diet induced thermogenesis ADRB2;ADRB1;TRPV4;TRPV1;ADRB3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ADRB2 GO:0046677| response to antibiotic SOD1;CYP1A1;ADRB3 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;DAGLA;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0045453| bone resorption ADRB2;GPR55 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;ADRB2;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;ADRB3;PLA2G1B;CACNA1I;ADRB1;PPARG;GPR18;SMPD1 GO:0042755| eating behavior ADRB3;OPRM1;OPRD1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB3;ADRB1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ADRB2 GO:0051100| negative regulation of binding CYP2D6 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB3;ADRB2;CNR1 GO:0001659| temperature homeostasis HTR2A;GPX1;ADRB1;TRPV1;ADRB3 GO:0009409| response to cold PPARG;TRPA1;ADRB1;ADRB3;TRPM8;ADRB2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG 19499:[DB14011 DB09092] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09092|Xanthinol RPL3;NNT;GAPDH;IDH3A;OGDH;MDH2 common genes common pathways GO:0006915| apoptotic process VDAC1;GAPDH;GPX1 GO:0009060| aerobic respiration CAT;MDH2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;MDH2;CYP17A1;ALOX15;CYP3A5;IDH3A;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;GAPDH;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;OGDH;GPX1;ALOX5;PTGS1;NNT GO:0061844| GAPDH;PLA2G1B GO:0072593| reactive oxygen species metabolic process NNT;SOD1 GO:0008152| metabolic process SMPD1;OGDH;ACAT1 19500:[DB14011 DB07693] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process CYP1B1;TTR GO:0006810| transport ABCC1;ABCG2;TRPV1;CACNA1I;TTR;TRPV2 GO:0043312| neutrophil degranulation ALOX5;TTR;CAT 19501:[DB14011 DB07253] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07253|N'-(5-chloro-1,3-benzodioxol-4-yl)-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine EPHB4 common genes common pathways GO:0001525| angiogenesis EPHB4;CYP1B1;PTGS2 GO:0007155| cell adhesion EPHB4;CYP1B1 19502:[DB14011 DB14059] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes PTGS2 common pathways GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0006351| transcription, DNA-dependent PPARG;NFKB2;NFKB1;RELA GO:0001889| liver development CYP1A1;RELA;ACAT1 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;PPARG GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0071260| cellular response to mechanical stimulus NFKB1;PTGS2 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;RELA;TRPA1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0050727| regulation of inflammatory response RELA;PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0061614| RELA;PPARG GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0010629| negative regulation of gene expression OPRD1;NFKB1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response CNR2;PTGS2;RELA;NFKB1;PTGS1;ALOX5;NFKB2;ALOX15;IDO1;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB2;PLA2G1B;RELA;CAT;NFKB1 GO:0016032| viral reproduction VDAC1;RELA;HTR2A GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;NFKB2;PPARG;SMPD1;CHRNA7;NFKB1;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0032868| response to insulin stimulus CAT;AANAT;RELA;TRPV4 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACAT1;AANAT;CYP1A2;RELA;PTGS2 GO:0070301| cellular response to hydrogen peroxide CYP1B1;RELA GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide IDO1;NFKB2;CYP1A1;CNR1;OPRM1;RELA;CYP1A2;CNR2;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning VDAC1;PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0045087| innate immune response NFKB1;NFKB2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RELA;NFKB1;PPARG;NFKB2;TRPV4;TRPV1 GO:0034097| response to cytokine stimulus NFKB2;PTGS2;RELA;AANAT GO:0043312| neutrophil degranulation ALOX5;CAT;NFKB1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;RELA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NFKB2;PPARG;NFKB1;RELA GO:0009612| response to mechanical stimulus TRPV4;PPARG;RELA GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process NFKB1;CAT;GPX1;SOD1;HMGCR;RELA;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0006355| regulation of transcription, DNA-dependent RELA;NFKB1;PPARG;NFKB2 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;RELA;PTGS2;SOD1;HTR2A GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;RELA;PPARG GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0043278| response to morphine RELA;OPRM1;CNR1 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;NFKB1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging HMGCR;PTGS2;RELA;SOD1;HTR2A;CNR1;NAPEPLD;CAT;NFKB2;CYP1A1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| GSR;PTGS2;GPX1;PTGS1;CAT GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0006915| apoptotic process GPX1;NFKB1;VDAC1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0043200| response to amino acid stimulus GLRB;GLRA3;RELA GO:0051591| response to cAMP RELA;AANAT GO:0048511| rhythmic process PPARG;NFKB2;AANAT GO:0071356| cellular response to tumor necrosis factor NFKB1;RELA;TRPV1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NFKB1;RELA GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;PTGS2;RELA;CYP1A2 19503:[DB14011 DB06064] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06064|KAI-1455 PRKCE common genes common pathways GO:0071380| cellular response to prostaglandin E stimulus PPARG;PRKCE GO:0010811| positive regulation of cell-substrate adhesion ALOX15;PRKCE GO:0007165| signal transduction CHRNA7;GPR55;PRKCE;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;CNR1;PRKCE;HMGCR GO:0035556| intracellular signal transduction PRKCE;PLA2G1B GO:0071361| cellular response to ethanol PRKCE;GLRA1 GO:0006915| apoptotic process VDAC1;PRKCE;GPX1 GO:0002376| immune system process IDO1;PRKCE GO:0043085| positive regulation of catalytic activity PRKCE;SOD1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;HTR2A;PRKCE GO:0071456| cellular response to hypoxia OPRD1;PTGS2;PRKCE;SLC29A1 GO:0043278| response to morphine OPRM1;PRKCE;CNR1 GO:0007155| cell adhesion CYP1B1;PRKCE GO:0030838| positive regulation of actin filament polymerization PRKCE;ALOX15 19504:[DB14011 DB08025] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08025|N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE MAPK10 common genes common pathways GO:0007165| signal transduction MAPK10;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0042752| regulation of circadian rhythm MAPK10;PPARG GO:0009416| response to light stimulus AANAT;MAPK10 GO:0048511| rhythmic process AANAT;MAPK10;PPARG GO:0000187| activation of MAPK activity MAPK10;PLA2G1B;SOD1;CHRNA7 GO:0010468| regulation of gene expression MAPK10;CYP1A2 19505:[DB14011 DB07517] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR;ALB GO:0001895| retina homeostasis SOD1;ALB 19506:[DB14011 DB08157] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CA2;SOD1;CYP1A2;PTGS2 GO:0001822| kidney development CAT;CA2 GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 19507:[DB14011 DB01309] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01309|Insulin Glulisine INSR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;INSR GO:0006355| regulation of transcription, DNA-dependent PPARG;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;GPX1 GO:0007612| learning PTGS2;VDAC1;INSR GO:0008284| positive regulation of cell proliferation INSR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0000187| activation of MAPK activity INSR;PLA2G1B;SOD1;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway INSR;PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;INSR GO:0042593| glucose homeostasis CNR1;TRPV4;INSR;PPARG GO:0001934| positive regulation of protein phosphorylation CHRNA7;INSR GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0035556| intracellular signal transduction INSR;PLA2G1B GO:0045740| positive regulation of DNA replication INSR;PLA2G1B GO:0032869| cellular response to insulin stimulus PLA2G1B;INSR;PPARG GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7;INSR 19508:[DB14011 DB00040] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;GLP2R GO:0042594| response to starvation GCGR;ACAT1;PPARG GO:0007611| learning or memory GLP1R;CNR1;CHRNA7 GO:0042593| glucose homeostasis GCGR;CNR1;TRPV4;PPARG GO:0007186| G-protein coupled receptor signaling pathway GCGR;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG;GLP1R;GLP2R GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger GCGR;CNR1;GLP2R GO:0008016| regulation of heart contraction CACNA1H;GLP1R GO:0007166| cell surface receptor linked signaling pathway GLP2R;GLP1R;TRPA1;TRPV1;GCGR GO:0065009| regulation of molecular function GCGR;TRPV1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GLP2R;GLP1R;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;GCGR GO:0050796| regulation of insulin secretion CNR1;GLP1R GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;TRPV4;TRPV1;OPRM1;HTR2A GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;GCGR;PTGS2 GO:0007584| response to nutrient PPARG;CNR1;GCGR;HMGCR GO:0045777| positive regulation of blood pressure GLP1R;CNR1 19509:[DB14011 DB04016] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04016|2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid CTSG;CMA1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;CMA1 GO:0006955| immune response CNR2;OPRD1;CTSG GO:0071333| cellular response to glucose stimulus SLC29A1;CMA1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CTSG;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0043312| neutrophil degranulation ALOX5;CTSG;CAT GO:0019731| antibacterial humoral response PLA2G1B;CTSG GO:0050830| defense response to Gram-positive bacterium CTSG;PLA2G1B GO:0045766| positive regulation of angiogenesis CYP1B1;CMA1;CHRNA7 GO:0050778| positive regulation of immune response CTSG;PLA2G1B 19510:[DB14011 DB11087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C19;NR1I2;CYP2C9;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006351| transcription, DNA-dependent NR1I2;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;SMPD1;NR1I2;GPR18;PPARG;PLA2G1B;CACNA1I GO:0042908| xenobiotic transport ABCG2;ABCC1;NR1I2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NR1I2;PPARG GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;NR1I2;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 19511:[DB14011 DB11988] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11988|Ocrelizumab MS4A1 common genes common pathways 19512:[DB14011 DB01700] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01700|AICA ribonucleotide ATIC common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;ATIC GO:0008152| metabolic process ACAT1;SMPD1;ATIC GO:0031100| organ regeneration ATIC;PPARG 19513:[DB14011 DB00994] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00994|Neomycin rpsL;CASR common genes common pathways GO:0006915| apoptotic process VDAC1;GPX1;CASR GO:0010628| positive regulation of gene expression TRPV4;CASR GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CASR;PPARG;GPR18 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1;CASR GO:0007635| chemosensory behavior CASR;TRPV1 GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CASR;CHRNA7;TRPV4;TRPM8 GO:0071404| cellular response to low-density lipoprotein particle stimulus CASR;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CASR;OPRM1;OPRD1;HTR2A GO:0070509| calcium ion import CACNA1H;CASR;CACNA1G;TRPV4;CACNA1I GO:0071333| cellular response to glucose stimulus CASR;SLC29A1 GO:0008284| positive regulation of cell proliferation CASR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0042311| vasodilation GPX1;CASR GO:0014070| response to organic cyclic compound ACAT1;AANAT;CASR;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0090280| positive regulation of calcium ion import TRPV2;CASR;TRPV3 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;CASR GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;CASR GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;CASR;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0006816| calcium ion transport CACNA1H;TRPV3;CASR;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1 GO:0051924| regulation of calcium ion transport OPRD1;CASR GO:0051592| response to calcium ion CASR;AANAT GO:0001503| ossification CASR;ALOX15 19514:[DB14011 DB05455] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05455|SR 121463 AVPR1B common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;AVPR1B;GPR18;PPARG GO:0007202| activation of phospholipase C activity AVPR1B;GPR55;HTR2A GO:0032870| cellular response to hormone stimulus AVPR1B;CACNA1H GO:0045907| positive regulation of vasoconstriction AVPR1B;PTGS2;HTR2A GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;AVPR1B;CACNA1I;PLA2G1B GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;AVPR1B;TRPV4;TRPV1 19515:[DB14011 DB03329] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03329|2-Pyridinethiol CTSB common genes common pathways GO:0046718| entry of virus into host cell HTR2A;CTSB GO:0046697| decidualization CTSB;PTGS2 GO:0030855| epithelial cell differentiation PPARG;CTSB;VDAC1 GO:0043312| neutrophil degranulation CTSB;CAT;ALOX5 19516:[DB14011 DB14034] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14034|Darglitazone PPARG common genes PPARG common pathways GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0060694| regulation of cholesterol transporter activity PPARG GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1 GO:1905461| PPARG GO:0007165| signal transduction HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0055088| lipid homeostasis PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0048469| cell maturation PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0032526| response to retinoic acid PPARG GO:0030308| negative regulation of cell growth PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG GO:0045087| innate immune response PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0030224| monocyte differentiation PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0071455| cellular response to hyperoxia PPARG 19517:[DB14011 DB04269] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04269|Cyclotheonamide A PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19518:[DB14011 DB03100] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03100|6-Nitroindazole NOS2;NOS3 common genes common pathways GO:0030324| lung development NOS3;CYP1A2 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1;NOS2 GO:0042311| vasodilation NOS3;GPX1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;NOS3;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;NOS2;CRYZ;CYP1A1;CYP2C9 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 GO:0001666| response to hypoxia CYP1A1;NOS2;CAT;CHRNA7 GO:0045776| negative regulation of blood pressure CNR1;NOS3;NOS2 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0009408| response to heat SOD1;TRPV3;TRPV2;NOS3;TRPV1 GO:0050796| regulation of insulin secretion NOS2;CNR1 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR;NOS3 GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1;NOS3 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:1902042| GPX1;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CYP1B1;PPARG;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PPARG;NOS3;PTGS2;SOD1;PTGS1 19519:[DB14011 DB05959] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05959|ENMD-1198 TNFRSF11A;HIF1A;STAT3 common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;STAT3 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;STAT3 GO:0042755| eating behavior STAT3;OPRM1;OPRD1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;HIF1A GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;STAT3;PTGS2;CYP1A2 GO:0032870| cellular response to hormone stimulus STAT3;CACNA1H GO:0007165| signal transduction PPARG;GPR18;SMPD1;TNFRSF11A;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;STAT3;OPRD1;CHRNA7;HIF1A GO:0071345| cellular response to cytokine stimulus STAT3;TRPV1 GO:0043434| response to peptide hormone stimulus STAT3;TRPV1 GO:0040014| regulation of multicellular organism growth STAT3;SOD1 GO:0006954| inflammatory response CNR2;PTGS2;STAT3;PTGS1;ALOX5;ALOX15;TNFRSF11A;IDO1;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFRSF11A;PLA2G1B;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFRSF11A;PPARG GO:0016032| viral reproduction VDAC1;HTR2A;STAT3 GO:0007595| lactation SLC29A1;HIF1A GO:0008542| visual learning HIF1A;HMGCR GO:0006879| cellular iron ion homeostasis ABCG2;HIF1A;SOD1 GO:0043524| negative regulation of neuron apoptosis HIF1A;SOD1 GO:0010629| negative regulation of gene expression HIF1A;OPRD1 GO:0009314| response to radiation CAT;OPRM1;PTGS2;TNFRSF11A GO:0001659| temperature homeostasis TRPV1;GPX1;HTR2A;STAT3 GO:0007399| nervous system development STAT3;GLRB;SMPD1 GO:0001503| ossification TNFRSF11A;ALOX15 GO:0006357| regulation of transcription from RNA polymerase II promoter STAT3;PPARG GO:0060259| regulation of feeding behavior STAT3;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production HIF1A;PTGS2;CYP1B1 GO:0001525| angiogenesis CYP1B1;PTGS2;HIF1A GO:0045821| positive regulation of glycolysis HIF1A;HTR2A GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;STAT3;OPRM1 GO:0006351| transcription, DNA-dependent PPARG;HIF1A;STAT3 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;HIF1A GO:0010628| positive regulation of gene expression HIF1A;STAT3;TRPV4 GO:0046716| muscle cell homeostasis SOD1;HIF1A GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;STAT3;PTGS2 GO:0034612| response to tumor necrosis factor TNFRSF11A;PTGS2 GO:0045766| positive regulation of angiogenesis CYP1B1;HIF1A;CHRNA7;STAT3 GO:0042593| glucose homeostasis STAT3;CNR1;HIF1A;PPARG;TRPV4 GO:0032355| response to estradiol stimulus PTGS2;STAT3;CYP1A2;CAT GO:0071456| cellular response to hypoxia OPRD1;PTGS2;HIF1A;SLC29A1 GO:0010468| regulation of gene expression HIF1A;CYP1A2 GO:0048514| blood vessel morphogenesis HIF1A;CYP1B1 GO:0007568| aging CYP1A1;NAPEPLD;CNR1;HTR2A;SOD1;STAT3;PTGS2;HMGCR;CAT GO:0061298| retina vasculature development in camera-type eye CYP1B1;HIF1A GO:0006355| regulation of transcription, DNA-dependent STAT3;HIF1A;PPARG GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;STAT3;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent HIF1A;STAT3;PPARG GO:0071407| cellular response to organic cyclic compound STAT3;CYP1B1;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter STAT3;HIF1A;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation TNFRSF11A;HMGCR;STAT3;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0043066| negative regulation of apoptotic process STAT3;PTGS2;HMGCR;SOD1;GPX1;HIF1A;CAT GO:0035722| interleukin-12-mediated signaling pathway SOD1;STAT3 GO:0034097| response to cytokine stimulus TNFRSF11A;PTGS2;STAT3;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;STAT3 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;CYP1A1;TNFRSF11A;IDO1 GO:0042127| regulation of cell proliferation PTGS1;HIF1A;PTGS2 19520:[DB14011 DB07559] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;DHODH;CYP1A2;PTGS2 GO:0007565| female pregnancy IDO1;DHODH GO:0007595| lactation SLC29A1;DHODH GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;DHODH;PTGS2;CNR1;SOD1 GO:0031000| response to caffeine DHODH;PPARG GO:0042493| response to drug CAT;DHODH;CYP1A2;PTGS2;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0055114| oxidation-reduction process CAT;DHODH;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0042594| response to starvation DHODH;ACAT1;PPARG 19521:[DB14011 DB04429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04429|4'-Hydroxyflavanone SHBG common genes common pathways 19522:[DB14011 DB05018] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05018|Migalastat GLA;UGT1A1 common genes common pathways GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;IDO1;CYP1A1;UGT1A1 GO:0042594| response to starvation PPARG;UGT1A1;ACAT1 GO:0043312| neutrophil degranulation ALOX5;CAT;GLA GO:0042493| response to drug SMPD1;ABCC1;UGT1A1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0006687| glycosphingolipid metabolic process GLA;SMPD1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;UGT1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;UGT1A1;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0051001| negative regulation of nitric-oxide synthase activity CNR2;CNR1;GLA GO:0010033| response to organic substance UGT1A1;TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0001889| liver development ACAT1;UGT1A1;CYP1A1 GO:0045471| response to ethanol UGT1A1;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1;CYP1A1;CYP2C19;CYP2D6 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0008152| metabolic process ACAT1;GLA;UGT1A1;SMPD1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;GLA GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;UGT1A1;PPARG;CYP1A1;TRPA1 GO:0007584| response to nutrient HMGCR;CNR1;UGT1A1;PPARG 19523:[DB14011 DB08692] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 19524:[DB14011 DB04881] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04881|Elacridar ABCB1;ABCG2;SLCO1B1 common genes ABCG2 common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;SLCO1B1;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8 GO:0046415| urate metabolic process ABCG2 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0006810| transport ABCG2;TRPV1;ABCB1;CACNA1I;ABCC1;TRPV2 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;ABCB1;CACNA1I;ABCG2;TRPM8;CACNA1H;TRPV3;SLCO1B1;TRPV2 GO:0033344| cholesterol efflux ABCG2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCB1;ABCG2 GO:0015886| heme transport ABCG2 19525:[DB14011 DB03962] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;PGD;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15 19526:[DB14011 DB08099] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08099|6-ethyl-5-[(2S)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine REN common genes common pathways GO:0008217| regulation of blood pressure PPARG;REN;PTGS1;SOD1;PTGS2 GO:0048469| cell maturation REN;PPARG GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;REN;SOD1;PTGS2;CYP1A2 GO:0051591| response to cAMP REN;AANAT GO:0042493| response to drug ABCG2;TRPA1;REN;CYP1A1;PPARG;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;REN GO:0001822| kidney development REN;CAT GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;IDO1;REN;CYP1A1 19527:[DB14011 DB08736] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08736|S,R-Warfarin alcohol ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR;ALB GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;ALB 19528:[DB14011 DB00695] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;PGD;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1A1;CYP2C9;CRYZ GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC2;UGT1A1;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0099133| ABCC2;ABCC1 GO:0042594| response to starvation ACAT1;UGT1A1;PPARG GO:0002576| platelet degranulation ALB;SOD1 GO:0001822| kidney development CAT;CA2 GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;ABCC2;CYP1A1;UGT1A1 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1;UGT1A1;CA2 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC22A5;SLC22A8;TRPV2;SLC22A11;SLC12A1;SLCO2A1;ABCC1;CACNA1G;SLC22A6;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCC2;TRPM8;ABCG2 GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;SLC12A1;CHRNA7;GLRA3 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0006979| response to oxidative stress ABCC2;SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0098869| ALB;GSR;PTGS2;GPX1;PTGS1;CAT GO:0006810| transport SLC12A1;TRPV2;ABCC2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;UGT1A1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:1902476| GLRA3;SLC12A1;GLRA1;GLRB GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009408| response to heat TRPV1;ABCC2;TRPV2;TRPV3;SOD1 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0007565| female pregnancy ABCC2;IDO1 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0008152| metabolic process UGT1A1;SMPD1;ACAT1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1;ACAT1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;UGT1A1;CYP1A1;CYP1A2;CYP3A4 GO:0043627| response to estrogen stimulus CA2;ABCC2;PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG;UGT1A1 GO:0098656| SLC22A6;VDAC1;SLC22A8 GO:0010043| response to zinc ion AANAT;CA2 GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCC1;SLC22A5 GO:0001895| retina homeostasis SOD1;ALB GO:0006811| ion transport TRPV2;SLC12A1;CHRNA7;SLC22A11;CACNA1H;TRPV3;SLC22A5;GLRA3;SLC22A8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;UGT1A1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1;CACNA1H GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 19529:[DB14011 DB13152] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13152|Coagulation Factor IX Human F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;F8;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0051897| positive regulation of protein kinase B signaling cascade F7;F10;GPX1 GO:0007623| circadian rhythm F7;AANAT GO:0002576| platelet degranulation F8;SOD1 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0001666| response to hypoxia CHRNA7;CAT;F7;CYP1A1 GO:0010977| negative regulation of neuron projection development LRP1;TRPV4 GO:0043277| apoptotic cell clearance LRP1;ALOX15 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;F7 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;PPARG;GPR18;F2 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CAT;LRP1;CYP1A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0031100| organ regeneration PPARG;F7 GO:0031667| response to nutrient levels SOD1;F7 GO:0043524| negative regulation of neuron apoptosis SOD1;LRP1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;LRP1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0042953| lipoprotein transport LRP1;PPARG GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;CYP1A1;PPARG;TRPA1;F7 GO:0008283| cell proliferation LRP1;CYP1A1;GPX1;HTR1A GO:0001523| retinoid metabolic process LRP1;NAPEPLD GO:0043627| response to estrogen stimulus PPARG;F7 GO:0061844| PLA2G1B;F2 GO:0009725| response to hormone stimulus ACAT1;F7 19530:[DB14011 DB09129] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09129|Chromic chloride INSR common genes common pathways GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0035556| intracellular signal transduction PLA2G1B;INSR GO:0045740| positive regulation of DNA replication PLA2G1B;INSR GO:0007613| memory INSR;CHRNA7;PTGS2;CNR1;HTR2A GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;INSR GO:0006355| regulation of transcription, DNA-dependent PPARG;INSR GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade INSR;GPX1 GO:0007612| learning INSR;VDAC1;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;INSR GO:0000187| activation of MAPK activity INSR;PLA2G1B;SOD1;CHRNA7 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;INSR GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;INSR;GPR18;PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;INSR;CNR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;INSR;OPRM1;PTGS2 19531:[DB14011 DB06796] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways GO:0001666| response to hypoxia CYP1A1;SLC11A2;CAT;CHRNA7 GO:0098869| PTGS2;PTGS1;GPX1;CAT;ALB;GSR GO:0006801| superoxide metabolic process SOD2;SOD1 GO:1902176| SOD2;GPX1 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;SOD2;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C9;CYP1A1;CRYZ GO:0002576| platelet degranulation ALB;SOD1;A2M GO:0035722| interleukin-12-mediated signaling pathway SOD2;SOD1 GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0007611| learning or memory CHRNA7;SLC11A2;CNR1 GO:0034599| cellular response to oxidative stress SOD1;SLC11A2;CAT;GPX1;GSR;SOD2 GO:0008217| regulation of blood pressure SOD2;PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation SOD2;CYP1B1;PPARG;OPRM1;PTGS2 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;TRPV3;CACNA1H;SLC11A2;GLRA3;TRPV2;CHRNA7 GO:0006919| activation of caspase activity SLC11A2;PPARG GO:0001895| retina homeostasis SOD1;ALB GO:0051289| protein homotetramerization CAT;TRPA1;CRYZ;SOD2;TRPV1;TRPM8 GO:0019430| removal of superoxide radicals SOD1;SOD2 GO:0006879| cellular iron ion homeostasis SOD1;SLC11A2;ABCG2 GO:0043524| negative regulation of neuron apoptosis SOD1;SOD2 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;SLC11A2;CYP1A2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;SOD2 GO:0000303| response to superoxide SOD1;SOD2 19532:[DB14011 DB06533] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06533|Ragaglitazar PPARA;PPARG common genes PPARG common pathways GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0015909| long-chain fatty acid transport PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CYP1A1;PPARA;CHRNA7;CAT GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARG;AANAT;PPARA GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PPARA GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;TRPV4;TRPV1;PPARG GO:0045087| innate immune response PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042060| wound healing PPARA;OPRM1;ALOX15 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG GO:0006631| fatty acid metabolic process PPARA;PTGS2;PTGS1;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG GO:0030224| monocyte differentiation PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1;PPARA GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0055088| lipid homeostasis PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0032868| response to insulin stimulus AANAT;CAT;PPARA;TRPV4 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0007507| heart development PPARA;PPARG GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;PPARA;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0048469| cell maturation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG 19533:[DB14011 DB06472] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0043277| apoptotic cell clearance ITGB3;ALOX15 GO:0042060| wound healing OPRM1;ALOX15;ITGB3 GO:0002576| platelet degranulation ITGB3;ITGA2B;SOD1 GO:0007155| cell adhesion ITGB3;CYP1B1;ITGA2B GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ITGB3 GO:0046718| entry of virus into host cell ITGB3;HTR2A GO:0060055| angiogenesis involved in wound healing ITGB3;GPX1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ITGB3 GO:0016032| viral reproduction HTR2A;ITGB3;VDAC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ITGB3 19534:[DB14011 DB07247] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;F7 GO:0031100| organ regeneration PPARG;F7 GO:0045766| positive regulation of angiogenesis F3;CHRNA7;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;F7 GO:0007623| circadian rhythm AANAT;F7 GO:0051897| positive regulation of protein kinase B signaling cascade F3;GPX1;F7 GO:0009725| response to hormone stimulus ACAT1;F7 GO:0014070| response to organic cyclic compound F7;PPARG;CYP1A1;TRPA1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0006919| activation of caspase activity PPARG;F3 GO:0043627| response to estrogen stimulus PPARG;F7 GO:0031667| response to nutrient levels F7;SOD1 19535:[DB14011 DB07140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;GPX1;PTGS1;DHFR;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 19536:[DB14011 DB00384] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes CYP1A2 common pathways GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;PTGS1;NAAA;GPX1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;SCNN1A;CACNA1H;SCNN1B;SCNN1D;SCNN1G GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0050896| response to stimulus TRPA1;TRPM8;SCNN1B;SCNN1D;SCNN1A;SCNN1G GO:0009791| post-embryonic development CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0006811| ion transport TRPV2;SCNN1G;CHRNA7;TRPV3;CACNA1H;SCNN1A;GLRA3;SCNN1B;SCNN1D;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0050891| multicellular organismal water homeostasis TRPV4;SCNN1G;SCNN1A;SCNN1B GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;TRPA1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0071615| oxidative deethylation CYP1A2 GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;TRPV1;GLRA3;SCNN1D;SCNN1B;SCNN1A;CHRNA7;SCNN1G GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 19537:[DB14011 DB05916] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05916|CT-011 PDCD1 common genes common pathways GO:0002376| immune system process IDO1;PDCD1 GO:0006915| apoptotic process VDAC1;GPX1;PDCD1 GO:0043066| negative regulation of apoptotic process PTGS2;PDCD1;HMGCR;SOD1;GPX1;CAT GO:0070234| positive regulation of T cell apoptosis IDO1;PDCD1 GO:0007165| signal transduction CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;PDCD1;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0043065| positive regulation of apoptotic process PDCD1;PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 19538:[DB14011 DB07814] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07814|Gibberellic acid AADACL2 common genes common pathways GO:0008152| metabolic process ACAT1;AADACL2;SMPD1 19539:[DB14011 DB01902] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;ERO1B;CYP2D6;CYP1A1;CYP2C9;CRYZ GO:0042593| glucose homeostasis TRPV4;ERO1B;PPARG;CNR1 GO:0045454| cell redox homeostasis GPX1;ERO1B;GSR 19540:[DB14011 DB00060] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00060|Interferon beta-1a IFNAR1;IFNAR2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;IFNAR2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;OPRM1;IFNAR1;CYP1A2;PTGS2;CNR2 GO:0009615| response to virus IFNAR2;IFNAR1;CYP1A1 19541:[DB14011 DB02568] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02568|Peldesine PNP common genes common pathways GO:0042493| response to drug ABCG2;SMPD1;ABCC1;CYP1A1;PNP;PPARG;TRPA1;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0006955| immune response CNR2;OPRD1;PNP GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 19542:[DB14011 DB04446] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04446|Benzo[B]Thiophene-2-Carboxamidine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 19543:[DB14011 DB04495] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04495|RU81843 SRC common genes common pathways GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0009615| response to virus SRC;CYP1A1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;SRC;GPX1;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug SRC;CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0002376| immune system process SRC;IDO1 GO:0071456| cellular response to hypoxia SRC;SLC29A1;PTGS2;OPRD1 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;SRC;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0042542| response to hydrogen peroxide CAT;GPX1;SRC;SOD1;TRPA1 GO:0043065| positive regulation of apoptotic process SRC;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7;SRC GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0045453| bone resorption SRC;GPR55 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC GO:0008283| cell proliferation CYP1A1;GPX1;SRC;HTR1A 19544:[DB14011 DB02271] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02271|S-(2-Oxo)Pentadecylcoa NMT2 common genes common pathways 19545:[DB14011 DB07079] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07079|3-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}propane-1-thiol ADAM17 common genes common pathways GO:0002446| neutrophil mediated immunity PLA2G1B;ADAM17 GO:0001666| response to hypoxia CYP1A1;ADAM17;CHRNA7;CAT GO:0008284| positive regulation of cell proliferation ADAM17;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0007155| cell adhesion CYP1B1;ADAM17 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;ADAM17;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;ADAM17 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;TRPA1;PPARG;ADAM17;CYP1A1;SMPD1;ABCC1;ABCG2 GO:0001934| positive regulation of protein phosphorylation ADAM17;CHRNA7 19546:[DB14011 DB02838] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02838|3,4-Dihydro-2h-Pyrrolium-5-Carboxylate DAO common genes common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;DAO;CYP2D6;GSR;IDO1;CYP2C19;CYP1A1;CYP2C9;CRYZ 19547:[DB14011 DB06750] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;SLCO1B3;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 19548:[DB14011 DB00743] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00743|Gadobenic acid ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0098869| PTGS2;GPX1;PTGS1;CAT;ALB;GSR 19549:[DB14011 DB03609] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03609|3-Deoxyguanosine PNP common genes common pathways GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0006955| immune response PNP;CNR2;OPRD1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PNP;PPARG;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 19550:[DB14011 DB13949] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways GO:0010033| response to organic substance CALR;CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent CALR;PPARG GO:0010628| positive regulation of gene expression TRPV4;CALR GO:0043277| apoptotic cell clearance ALOX15;ITGB3 GO:0007283| spermatogenesis CALR;CNR1;SOD1 GO:0006874| cellular calcium ion homeostasis CALR;TRPM8;TRPV4;GPR12;HTR2A;CHRNA7 GO:0032355| response to estradiol stimulus CALR;PTGS2;CYP1A2;CAT GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;CALR;SMPD1;ABCC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;CALR;PPARG GO:0007155| cell adhesion ITGB3;CYP1B1 GO:0002576| platelet degranulation ITGB3;TF;SOD1 GO:0008284| positive regulation of cell proliferation CALR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0042060| wound healing ITGB3;ALOX15;OPRM1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;TFRC GO:0045740| positive regulation of DNA replication PLA2G1B;CALR GO:0001895| retina homeostasis SOD1;TF GO:0010745| negative regulation of macrophage derived foam cell differentiation ITGB3;PPARG GO:0006811| ion transport GLRA3;TF;TRPV3;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1 GO:0060055| angiogenesis involved in wound healing GPX1;ITGB3 GO:0046718| entry of virus into host cell ITGB3;TFRC;HTR2A GO:0006879| cellular iron ion homeostasis SOD1;TF;TFRC;ABCG2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ITGB3 GO:0016032| viral reproduction ITGB3;VDAC1;TFRC;HTR2A GO:0001934| positive regulation of protein phosphorylation ITGB3;CHRNA7 19551:[DB14011 DB04791] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04791|2-O-(4'-AMIDINOPHENYL)-5-O-(3''-AMIDINOPHENYL)-1,4:3,6-DIANHYDRO-D-SORBITOL PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 19552:[DB14011 DB08756] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08756|(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE PRKACA;PKIA;ROCK1;ROCK2 common genes common pathways GO:0042752| regulation of circadian rhythm ROCK2;PPARG GO:1902430| CHRNA7;ROCK1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ROCK2 GO:0043524| negative regulation of neuron apoptosis ROCK1;SOD1 GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0035556| intracellular signal transduction ROCK2;PLA2G1B;ROCK1 GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;ROCK1 GO:0006939| smooth muscle contraction ROCK2;ROCK1;HTR2A GO:0016525| negative regulation of angiogenesis ROCK1;ROCK2;PPARG GO:0043312| neutrophil degranulation ROCK1;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PKIA;PPARG GO:0071333| cellular response to glucose stimulus SLC29A1;PRKACA GO:0048511| rhythmic process ROCK2;PPARG;AANAT GO:0010628| positive regulation of gene expression ROCK2;ROCK1;TRPV4 GO:0006915| apoptotic process GPX1;VDAC1;ROCK1 GO:0034605| cellular response to heat TRPV4;TRPV1;PRKACA;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;ROCK2;ROCK1 19553:[DB14011 DB04404] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04404|Allosamizoline CHIT1 common genes common pathways GO:0043312| neutrophil degranulation CHIT1;CAT;ALOX5 GO:0008152| metabolic process ACAT1;SMPD1;CHIT1 GO:0006955| immune response OPRD1;CNR2;CHIT1 19554:[DB14011 DB01092] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes CYP1A1 common pathways GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0008542| visual learning ATP1A2;ATP1A3;HMGCR GO:0009635| response to herbicide CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0071260| cellular response to mechanical stimulus ATP1A2;PTGS2;ATP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0009692| ethylene metabolic process CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0070988| demethylation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 GO:0051966| regulation of synaptic transmission, glutamatergic CNR1;ATP1A2 GO:0070365| hepatocyte differentiation CYP1A1 GO:0008217| regulation of blood pressure PPARG;ATP1A2;PTGS1;SOD1;ATP1A1;PTGS2 GO:0098656| VDAC1;SLC22A8 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0006811| ion transport SLCO1B3;GLRA3;SLC22A8;SLCO1B1;ATP1A1;CACNA1H;TRPV3;SLCO1A2;CHRNA7;TRPV2;GLRA1;TRPA1;ATP1A3;CACNA1G;ATP1A2;SLCO1C1;SLCO4C1;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0009624| response to nematode CYP1A1 GO:0008344| adult locomotory behavior OPRD1;ATP1A2;ATP1A3 GO:0043010| camera-type eye development CYP1A1 GO:0097267| CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:1900087| CYP1A1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1 GO:0007613| memory ATP1A3;CHRNA7;HTR2A;CNR1;PTGS2 GO:0032502| developmental process CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0009308| amine metabolic process CYP1A1 GO:0035094| response to nicotine CNR1;CHRNA7;ATP1A2 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ATP1A1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;ATP1A3;TRPA1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0032094| response to food OPRM1;CYP1A1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1 GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0071300| cellular response to retinoic acid ATP1A3;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;SLCO4C1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0051481| reduction of cytosolic calcium ion concentration ATP1A2;OPRM1 GO:0007283| spermatogenesis CNR1;SOD1;SLCO4C1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0034220| ion transmembrane transport ATP1A2;ATP1A3;GLRA1;TRPA1;TRPV1;GLRB;ATP1A1;GLRA3;CHRNA7 GO:0002933| CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0086002| CACNA1G;ATP1A1 GO:0055085| transmembrane transport TRPA1;SLCO1C1;ABCC1;CACNA1G;TRPM8;ABCG2;SLCO4C1;TRPV1;VDAC1;CACNA1I;TRPV4;SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2;TRPV3;CACNA1H;TRPV2 GO:0002087| regulation of respiratory gaseous exchange by neurological system process ATP1A2;GLRA1 GO:0010041| response to iron(III) ion CYP1A1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0009611| response to wounding CYP1A1;GPX1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0007568| aging CAT;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CYP1A1 19555:[DB14011 DB01428] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01428|Oxybenzone PGR;AR;ESR1;ESR2 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 GO:0006810| transport TRPV2;AR;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0010468| regulation of gene expression CYP1A2;AR GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;ESR2;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;PLA2G1B;ESR2;PPARG;AR;ESR1 GO:0008284| positive regulation of cell proliferation AR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR;PPARG;PGR;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;PPARG;ESR2;PGR GO:0007165| signal transduction PPARG;GPR18;SMPD1;ESR2;PGR;PLA2G1B;CACNA1I;GPR55;HTR1A;ESR1;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;AR;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV4;TRPV1 GO:0008285| negative regulation of cell proliferation AR;PTGS2;OPRM1;CYP1B1;PPARG GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0007548| sex differentiation CYP17A1;AR GO:0008283| cell proliferation CYP1A1;GPX1;AR;HTR1A GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;PGR;ESR2;ESR1;AR GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;PPARG;ESR2;PGR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;AR;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression PGR;ESR1;OPRD1 19556:[DB14011 DB07772] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07772|(1R)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 19557:[DB14011 DB01077] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways GO:0006879| cellular iron ion homeostasis ABCG2;ATP6V1A;SOD1 GO:0006811| ion transport CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;ATP6V1A;CHRNA7;TRPV3;CACNA1H;GLRA3 GO:0007155| cell adhesion PTPRS;CYP1B1 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;ATP6V1A;CHRNA7;GLRA3 GO:0010977| negative regulation of neuron projection development PTPRS;TRPV4 GO:0006810| transport ABCC1;ABCG2;TRPV1;CACNA1I;ATP6V1A;TRPV2 19558:[DB14011 DB03255] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03255|Phenol cobT;ALB common genes common pathways GO:0001895| retina homeostasis ALB;SOD1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0098869| ALB;GSR;PTGS2;CAT;GPX1;PTGS1 19559:[DB14011 DB07437] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07437|1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE UPP1 common genes common pathways GO:0006139| nucleobase-containing compound metabolic process UPP1;SLC29A1 19560:[DB14011 DB07710] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07710|PHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CA2;TRPA1;PPARG;CYP1A1 19561:[DB14011 DB05125] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05125|SC12267 DHODH common genes common pathways GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;DHODH;CAT GO:0055114| oxidation-reduction process CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;DHODH;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0031000| response to caffeine DHODH;PPARG GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy IDO1;DHODH GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;DHODH;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;DHODH;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 19562:[DB14011 DB04892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04892|Phenserine ACHE;BCHE;APP common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;PLA2G1B;CAT GO:0008542| visual learning HMGCR;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;APP GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;GLRB;VDAC1;GLRA1;APP;CACNA1G GO:0010629| negative regulation of gene expression APP;OPRD1 GO:0071320| cellular response to cAMP APP;AANAT GO:1902004| APP;CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;APP;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:1990090| APP;TRPV1 GO:0007399| nervous system development APP;SMPD1;GLRB;ACHE GO:0001774| microglial cell activation APP;TRPV1 GO:0008285| negative regulation of cell proliferation PPARG;BCHE;APP;CYP1B1;OPRM1;PTGS2 GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0061844| APP;PLA2G1B GO:0032930| positive regulation of superoxide anion generation APP;SOD1 GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 GO:0008344| adult locomotory behavior OPRD1;APP GO:1900273| CHRNA7;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;APP GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2;APP GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;APP;HTR2A;OPRM1 GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0007517| muscle organ development ACHE;CACNA1H GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;BCHE;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0019731| antibacterial humoral response APP;PLA2G1B GO:0050808| synapse organization CHRNA7;APP GO:0002576| platelet degranulation APP;SOD1 GO:0007626| locomotory behavior OPRM1;SOD1;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;APP;PLA2G1B GO:0010288| response to lead ion APP;CAT GO:0007155| cell adhesion CYP1B1;APP;ACHE GO:0045087| innate immune response PPARG;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;APP GO:0007611| learning or memory APP;CNR1;CHRNA7 GO:0008203| cholesterol metabolic process CAT;HMGCR;APP GO:0007612| learning PTGS2;VDAC1;APP;BCHE GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:1905906| CHRNA7;APP GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0051262| protein tetramerization APP;ACHE;HMGCR;CAT GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0000187| activation of MAPK activity APP;PLA2G1B;SOD1;CHRNA7 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0006915| apoptotic process VDAC1;APP;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;APP;ALOX15;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;APP;TRPV1 GO:0006979| response to oxidative stress APP;PTGS2;SOD1;PTGS1;GPX1;CAT GO:0051260| protein homooligomerization APP;GLRA1;GLRA3;ACAT1 GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0098815| CHRNA7;APP GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;APP;PPARG;GPR18 GO:0010468| regulation of gene expression APP;CYP1A2 19563:[DB14011 DB05487] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0032496| response to lipopolysaccharide IDO1;NFKB2;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0034097| response to cytokine stimulus NFKB2;PTGS2;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;NFKB2;NFKB1;ESR1 GO:0045087| innate immune response PPARG;NFKB2;NFKB1 GO:0043312| neutrophil degranulation NFKB1;CAT;ALOX5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NFKB2;PLA2G1B;ESR1;NFKB1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;NFKB1 GO:0006355| regulation of transcription, DNA-dependent PPARG;NFKB2;NFKB1;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0050728| negative regulation of inflammatory response NFKB1;CNR2 GO:0007568| aging CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;NFKB2;CYP1A1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 GO:0006915| apoptotic process VDAC1;NFKB1;GPX1 GO:0071356| cellular response to tumor necrosis factor NFKB1;TRPV1 GO:0048511| rhythmic process PPARG;NFKB2;AANAT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NFKB1 GO:0006351| transcription, DNA-dependent NFKB2;PPARG;NFKB1;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter NFKB1;ESR1;PPARG GO:0071260| cellular response to mechanical stimulus NFKB1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1;NFKB1 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;NFKB1;NFKB2;TRPV1;ALOX15;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;CAT;NFKB2;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ESR1;HTR2A;OPRM1 GO:0007165| signal transduction ESR1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;NFKB1;CHRNA7;PPARG;NFKB2;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 19564:[DB14011 DB04442] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04442|2-(2-Oxo-1,2-Dihydro-Pyridin-3-Yl)-1h-Benzoimidazole-5-Carboxamidine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19565:[DB14011 DB02761] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways GO:0030855| epithelial cell differentiation PPARG;TST;VDAC1 19566:[DB14011 DB08201] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08201|(1S)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;BCHE;TRPA1;PPARG;CYP1A1;ABCG2 GO:0007612| learning PTGS2;VDAC1;BCHE GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;BCHE GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE 19567:[DB14011 DB04761] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04761|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] MMP13 common genes common pathways GO:0030282| bone mineralization MMP13;ALOX15;PTGS2 19568:[DB14011 DB08077] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HBB GO:0098869| PTGS2;PTGS1;GPX1;CAT;HBA1;HBB;GSR GO:0042744| hydrogen peroxide catabolic process HBA1;HBB;CAT;GPX1 GO:0043312| neutrophil degranulation HBB;CAT;ALOX5 GO:0051291| protein heterooligomerization HBB;GLRA1;HBA1;GLRB GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;HBB GO:0042542| response to hydrogen peroxide TRPA1;HBB;HBA1;CAT;GPX1;SOD1 GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB 19569:[DB14011 DB14533] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes GLRA1;SOD1 common pathways GO:0006879| cellular iron ion homeostasis ABCG2;CP;TF;SOD1 GO:0008542| visual learning HMGCR;APP GO:1902476| GLRB;GLRA1;GLRA3;APOL1 GO:0051924| regulation of calcium ion transport OPRD1;AGT GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;TP53;VTN;HTR2A;IL3;AGT;INS GO:0019430| removal of superoxide radicals SOD1;MT3;APOA4;PRDX1 GO:0007595| lactation NME1;SLC29A1 GO:0060013| righting reflex GLRB;GLRA1 GO:0043087| regulation of GTPase activity SOD1 GO:0001964| startle response GLRB;GLRA1 GO:0016032| viral reproduction TP73;VDAC1;CFH;IDE;HDAC1;APOA2;TP53;MDM2;SIVA1;HTR2A GO:0006955| immune response C8B;C1R;JCHAIN;IGKV1-17;C1QC;C3;IGHA1;C8A;OPRD1;IGLV3-21;VTN;CNR2;IL3 GO:0019226| transmission of nerve impulse SOD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JUP;ESR1;HDAC4;PPARG;APP GO:1902430| CHRNA7;APOE;CLU GO:0010942| positive regulation of cell death PTGS2;MT3;HBA1;HBB GO:0006954| inflammatory response ALOX15;IDO1;SERPINA3;TRPV1;KNG1;KRT16;HDAC4;BDKRB1;C4B;PTGS1;ALOX5;C5;C3;KLKB1;PTGS2;CNR2;S100A8;S100A9 GO:0010976| positive regulation of neuron projection development APOE;NME1;AGT;CNR1 GO:0009408| response to heat TRPV1;TRPV2;TRPV3;SOD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity INS;CAT;AGT;S100A8;S100A9;PLA2G1B;CLU;APP GO:0051289| protein homotetramerization IDE;TRPA1;CRYZ;ALDOA;TP53;TRPM8;TRPV1;CAT GO:1902004| CHRNA7;APOE;CLU;APP GO:0007565| female pregnancy IDO1;PZP;AGT GO:0001934| positive regulation of protein phosphorylation MT3;CHRNA7;C3;F2;MMP9;APP GO:0043534| blood vessel endothelial cell migration APOA1;GPX1 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;PTGS2;GPX1;MT3 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0031667| response to nutrient levels PSPH;PON1;SOD1 GO:0045859| regulation of protein kinase activity SOD1 GO:0071603| endothelial cell-cell adhesion CYP1B1;JUP GO:0071320| cellular response to cAMP APP;AANAT GO:0043524| negative regulation of neuron apoptosis SOD1;MT3;APOE;HDAC1;TP73 GO:0007268| synaptic transmission OPRD1;OPRM1;GLRA3;HTR2A;VDAC1;GLRB;APP;CACNA1G;GLRA1 GO:0010629| negative regulation of gene expression MDM2;APP;HDAC1;OPRD1;ESR1;AGT;NME1;HDAC8 GO:0071260| cellular response to mechanical stimulus AGT;PTGS2;HDAC4 GO:0042572| retinol metabolic process CYP1B1;TTR GO:0097305| GLRA1 GO:0051974| negative regulation of telomerase activity TP53;PPARG GO:0071361| cellular response to ethanol GLRA1 GO:0006629| lipid metabolic process PTGS2;APOL1;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PON1;C3;GPX1;NAAA;PTGS1;APOE;CLU;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;APOBR;DAGLA;APOA1 GO:0007399| nervous system development GLRB;APP;SMPD1;APLP1;HDAC4;IL3;NME1 GO:0002027| regulation of heart rate MDM2;CACNA1G;AGT GO:1990090| APP;TRPV1 GO:0001503| ossification MMP9;AHSG;ALOX15 GO:0007507| heart development MDM2;PPARG GO:0008152| metabolic process ACAT1;TPI1;CPE;IDE;ASPA;SMPD1 GO:0042310| vasoconstriction AGT;HTR1A GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;HBA1;TRPA1;HBB GO:0042307| positive regulation of protein import into nucleus PTGS2;JUP GO:0043065| positive regulation of apoptotic process IDO1;KNG1;TP73;CYP1B1;TRPV1;MMP9;PPARG;SMPD1;APP;TP53;CLU;SOD1;CNR1;PTGS2 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0071312| cellular response to alkaloid TRPV1;MDM2 GO:0050727| regulation of inflammatory response AHSG;PGLYRP2;ESR1;S100A8;PTGS2;S100A9 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0006351| transcription, DNA-dependent EEF1A1;HDAC1;HDAC4;PPARG;TP53;TP73;ENO1;ESR1;PARP1;HDAC8 GO:0045773| positive regulation of axon extension TRPV2;FN1 GO:0045541| negative regulation of cholesterol biosynthetic process SOD1;APOE GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2;TRPA1;BDKRB1;TRPV1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0051592| response to calcium ion AANAT;PDCD6;FGA GO:0045821| positive regulation of glycolysis HTR2A;INS;GAPDHS GO:0045471| response to ethanol TUFM;TP53;CAT;MGMT;CNR1;SOD1;S100A8;GSN;OPRM1;HMGCR GO:0000060| protein import into nucleus, translocation MT3;OPRD1 GO:0045776| negative regulation of blood pressure CNR1;BDKRB1 GO:0001525| angiogenesis PDCD6;CYP1B1;S100A7;FN1;PTGS2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1;AGT;C5 GO:0000303| response to superoxide SOD1 GO:0071294| cellular response to zinc ion PARP1;GLRA1;MT1A;MT2A GO:0061045| negative regulation of wound healing APCS;HMGCR GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;C3;C5;PTGS2 GO:0086091| JUP;CACNA1G;DSP GO:0008090| retrograde axon cargo transport SOD1 GO:0001774| microglial cell activation APP;CLU;TRPV1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG;APOE GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0008217| regulation of blood pressure PTGS1;AGT;PTGS2;SOD1;PPARG;HBB GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;APOE GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;NME1;APP;TP53;HDAC1;PPARG;HDAC4;TP73;CYP1B1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;MDM2 GO:0032930| positive regulation of superoxide anion generation AGT;SOD1;APP GO:0061844| APP;S100A7;SEMG1;KNG1;F2;PLA2G1B;S100A9;KRT6A;DCD GO:0007584| response to nutrient HMGCR;CNR1;APOA1;PPARG GO:1902042| GPX1;FGA GO:0043627| response to estrogen stimulus ESR1;PPARG;APOA2;APOA1 GO:0001523| retinoid metabolic process TTR;NAPEPLD;APOA1;APOA2;APOE;APOA4 GO:0048146| positive regulation of fibroblast proliferation FN1;PLA2G1B;ESR1;AGT GO:0045740| positive regulation of DNA replication IL3;INS;PLA2G1B GO:0001890| placenta development SOD1;PPARG GO:0051291| protein heterooligomerization GLRB;GLRA1;IDE;HBB;HBA1;SEMG1;JUP GO:0055088| lipid homeostasis PPARG;APOE;APOA4 GO:0010043| response to zinc ion KRT14;AANAT;S100A8 GO:0006749| glutathione metabolic process GSR;SOD1;GPX1 GO:0071276| cellular response to cadmium ion GSN;CYP1A2;SOD1;MT3;MMP9;MT1A GO:0030336| negative regulation of cell migration CYP1B1;KRT16 GO:0034976| response to endoplasmic reticulum stress PDIA3;ALOX15;P4HB GO:0045777| positive regulation of blood pressure CNR1;AGT GO:0042633| hair cycle KRT14;KRT16;PTGS2 GO:0008344| adult locomotory behavior OPRD1;APP GO:0001895| retina homeostasis JCHAIN;PRDX1;KRT1;SOD1;IGHA1;TF GO:0040029| regulation of gene expression, epigenetic GPX1;HDAC4 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0046470| phosphatidylcholine metabolic process PON1;PLA2G1B;APOA4 GO:0044240| multicellular organismal lipid catabolic process APOA4;PLA2G1B GO:0015949| nucleobase-containing small molecule interconversion GSR;NME1 GO:0009395| phospholipid catabolic process APOA2;NAPEPLD GO:0002227| innate immune response in mucosa PLA2G1B;APOA4 GO:0014070| response to organic cyclic compound ACAT1;AANAT;MGMT;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1;TP53 GO:0009636| response to toxin PON1;MGMT;GPX1;CAT;MDM2;CYP1A1;CYP1B1 GO:0006919| activation of caspase activity PDCD6;PPARG;S100A8;S100A9 GO:0046620| regulation of organ growth SOD1 GO:0009411| response to UV TP53;CAT GO:0008283| cell proliferation TP53;CYP1A1;KRT16;PRDX1;HTR1A;GPX1;MT3 GO:0032088| negative regulation of NF-kappaB transcription factor activity SIVA1;CAT;CYP1B1 GO:2000378| negative regulation of reactive oxygen species metabolic process MT3;VDAC1 GO:0006811| ion transport GLRA3;CACNA1H;TF;TRPV3;CHRNA7;CP;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1 GO:0046340| diacylglycerol catabolic process DAGLA;APOA2 GO:0010332| response to gamma radiation PARP1;GPX1;TP53;TP73 GO:0065009| regulation of molecular function TRPV1;AGT;IL3 GO:0070542| response to fatty acid CAT;PTGS2;PON1 GO:0034644| cellular response to UV PTGS2;TP53;TP73 GO:0006641| triglyceride metabolic process APOBR;APOA2;APOE;CAT;GPX1 GO:0007420| brain development ACAT1;MT3 GO:0090336| positive regulation of brown fat cell differentiation PTGS2;INS GO:0007165| signal transduction ESR1;HTR1A;GPR55;HTR2A;C3;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7;JUP;PPARG;GPR18;BDKRB1;PDIA3;SMPD1;IGFALS;CACNA1I;PLA2G1B;FGA GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP GO:2000344| positive regulation of acrosome reaction GLRA1;CACNA1H GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;FGA GO:0006821| chloride transport GLRA1;GLRB;GLRA3 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;FGA GO:0010811| positive regulation of cell-substrate adhesion VTN;ALOX15 GO:0001819| positive regulation of cytokine production SOD1;AGT GO:1900273| APP;CHRNA7;INS GO:0048662| negative regulation of smooth muscle cell proliferation TP53;PPARG GO:0060047| heart contraction GPX1;SOD1 GO:0002262| myeloid cell homeostasis SOD1 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;APP GO:0032869| cellular response to insulin stimulus PARP1;PLA2G1B;PPARG GO:0007204| elevation of cytosolic calcium ion concentration AGT;ESR1;HTR2A;OPRM1;TRPV1;TRPV4;KNG1;BDKRB1;APP GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0007613| memory APP;CHRNA7;CNR1;HTR2A;PTGS2 GO:0001975| response to amphetamine CNR2;SOD1;HDAC1 GO:0045454| cell redox homeostasis GSR;PRDX1;PDIA3;GPX1;P4HB GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0060012| synaptic transmission, glycinergic GLRB;GLRA1;GLRA3 GO:0046718| entry of virus into host cell SIVA1;HTR2A;IDE GO:0050729| positive regulation of inflammatory response AGT;S100A9;S100A8;TRPV4 GO:0040014| regulation of multicellular organism growth APP;SOD1 GO:0007566| embryo implantation PTGS2;SOD1;MMP9 GO:0019216| regulation of lipid metabolic process AGT;HMGCR;CNR1;SERPINA3;APOA1;APOA2;CYP1A1;PPARG GO:0090201| negative regulation of release of cytochrome c from mitochondria CLU;GPX1 GO:0051384| response to glucocorticoid stimulus APOA2;CPN1;PTGS2 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0050890| cognition CHRNA7;INS GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0060326| cell chemotaxis ABCC1;C5 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INS;APP GO:0007015| actin filament organization ALDOA;PLA2G1B;TRPV4 GO:0016525| negative regulation of angiogenesis PPARG;AGT GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0043278| response to morphine MDM2;OPRM1;CNR1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PON1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;HDAC4 GO:0034465| response to carbon monoxide SOD1 GO:0010243| response to organic nitrogen TP53;TRPV1;TP73;PTGS2 GO:0050728| negative regulation of inflammatory response APOE;APOA1;CNR2;KRT1 GO:0006801| superoxide metabolic process SOD1;CCS GO:0055093| response to hyperoxia CAT;CYP1A1;HDAC1;TP53 GO:0055114| oxidation-reduction process CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;PRDX1;CYP1B1;GAPDHS;CRYZ;CYP1A1;CYP2C9;PDIA3;ADH1C;CAT;CP;ALOX5;GPX1;PTGS1;CCS;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;P4HB GO:0050884| neuromuscular process controlling posture GLRA1 GO:0007569| cell aging TP53;SOD1 GO:0050808| synapse organization CHRNA7;APP GO:0019731| antibacterial humoral response APP;IGHM;SEMG1;PLA2G1B;JCHAIN;IGHA1 GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0051702| interaction with symbiont FN1;GPX1 GO:1902176| INS;GPX1 GO:0007517| muscle organ development CACNA1H;UTRN GO:0045893| positive regulation of transcription, DNA-dependent AGT;MT3;ESR1;TP73;TP53;HDAC1;HDAC4;PPARG GO:0006631| fatty acid metabolic process C3;PTGS2;PTGS1;ALOX15 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0071407| cellular response to organic cyclic compound CYP1B1;MDM2;CYP1A1;MGMT GO:0006355| regulation of transcription, DNA-dependent INS;HDAC8;PARP1;ESR1;ENO1;TP73;TP53;HDAC4;PPARG;EEF1A1;HDAC1 GO:0030593| neutrophil chemotaxis S100A8;S100A9;PLA2G1B GO:0010666| positive regulation of cardiac muscle cell apoptosis AGT;HMGCR GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;MGMT;NME1;CAT;MDM2;SMPD1;TP53;APOA2;ABCC1;HDAC1;TRPA1;HDAC4;PPARG;CYP1A1;TP73;APOA1;ABCG2 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP;PGLYRP2;KRT6A;DCD GO:0018158| protein oxidation GPX1;APOA1;APOA2 GO:0050905| neuromuscular process GLRA1;GLRB GO:0043312| neutrophil degranulation DSP;AHSG;A1BG;SERPINA3;S100A7;MMP9;HBB;EEF1A1;ORM2;ALDOA;SERPINA1;KRT1;CAT;TTR;JUP;ALOX5;HRNR;C3;S100A9;GSN;S100A8 GO:0010288| response to lead ion APP;CAT GO:0007628| adult walking behavior GLRB;GLRA1 GO:0045087| innate immune response CFB;JCHAIN;FCN3;CFH;FGA;PPARG;KRT16;IGHM;S100A7;CLU;C8B;C1QB;C1R;APP;C4BPA;PGLYRP2;C4B;C8G;IGHA1;C5;C1S;C1QC;CFI;C3;APOL1;S100A8;S100A9;C8A;APCS;C4BPB;F12 GO:0007155| cell adhesion JUP;VTN;CYP1B1;IGFALS;APP;FN1;APLP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC4;PPARG;HDAC1;APP;TP53;MDM2;ENO1;TRPV4;TP73;TRPV1;ESR1;PARP1;HDAC8 GO:0034097| response to cytokine stimulus TP53;AANAT;PTGS2;ITIH4 GO:0035722| interleukin-12-mediated signaling pathway P4HB;SOD1;CA1 GO:0009612| response to mechanical stimulus TRPV4;BDKRB1;PSPH;PPARG GO:0043066| negative regulation of apoptotic process HDAC1;MMP9;TP53;MDM2;MGMT;SOD1;PTGS2;HMGCR;CAT;MT3;GPX1 GO:0042311| vasodilation KNG1;APOE;AGT;GPX1 GO:0001822| kidney development AGT;CAT;TP73 GO:1902177| SOD1 GO:0032259| methylation MGMT;CYP1A2 GO:0008284| positive regulation of cell proliferation FN1;HDAC4;HDAC1;MDM2;F2;HTR1A;HTR2A;PTGS2;KRT6A;HMGCR;INS;CHRNA7;IL3;AGT GO:0007340| acrosome reaction GLRA1;GLRB GO:0007626| locomotory behavior APP;SOD1;OPRM1 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;GLRA3;CPE;OPRD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;HDAC4;HDAC1;TP53;APP;PLA2G1B;TP73;ESR1;PARP1 GO:0009615| response to virus CYP1A1;CLU;ENO1 GO:0002576| platelet degranulation TF;ITIH4;APLP2;SOD1;A2M;SERPINA1;SERPINA4;ALDOA;CLU;ORM2;APP;FN1;SERPINA3;A1BG;KNG1;FGA;ITIH3;AHSG;APOA1 GO:0046677| response to antibiotic SOD1;CYP1A1;MDM2;TP53 GO:1905906| APOE;APP;CHRNA7 GO:0001660| fever generation TRPV1;IL3 GO:0014824| artery smooth muscle contraction HTR2A;AGT GO:0030317| sperm motility CACNA1I;GAPDHS GO:0071333| cellular response to glucose stimulus SLC29A1;NME1 GO:0006695| cholesterol biosynthetic process HMGCR;APOA4;APOA1 GO:0043542| endothelial cell migration S100A2;CYP1B1 GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:0032526| response to retinoic acid PPARG;TP53 GO:0097332| SOD1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;GLRB;TRPV1;GLRA1 GO:0033344| cholesterol efflux APOA4;APOE;APOA2;ABCG2;APOA1 GO:0071230| cellular response to amino acid stimulus GLRA1 GO:0034599| cellular response to oxidative stress HDAC1;GSR;PRDX1;MGMT;SOD1;P4HB;PARP1;CAT;MT3;CCS;GPX1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGT;OPRD1;OPRM1;HTR2A;ESR1 GO:0007611| learning or memory CNR1;CHRNA7;APP GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0030308| negative regulation of cell growth BDKRB1;TP53;PPARG;ENO1;AGT;MT3 GO:0001508| regulation of action potential GLRA1;CACNA1G GO:0000302| response to reactive oxygen species PRDX1;S100A7;APOE;CAT;GPX1;SOD1 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;S100A8;CYP1A2;CNR1;IDO1;BDKRB1;CYP1A1;HDAC1;S100A7 GO:0042060| wound healing FN1;TP53;ALOX15;DSP;S100A8;OPRM1;GSN;KRT6A;INS GO:0042127| regulation of cell proliferation JUP;AGT;PTGS1;PTGS2 GO:0008203| cholesterol metabolic process CAT;APOL1;HMGCR;PON1;APOBR;APOA1;APOE;APOA4;APOA2;APP GO:0007612| learning PTGS2;APP;VDAC1 GO:0045892| negative regulation of transcription, DNA-dependent ENO1;HDAC1;HDAC4;PPARG;MDM2;TP53;MT3 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1 GO:0015758| glucose transport INS;PLA2G1B GO:0051262| protein tetramerization TP73;APP;TP53;CAT;HMGCR GO:0031000| response to caffeine HDAC1;PPARG;TP53 GO:0006644| phospholipid metabolic process PLA2G1B;APOA1;NAPEPLD GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;APOE GO:0048714| positive regulation of oligodendrocyte differentiation TP73;PPARG;HDAC1;ASPA GO:0046716| muscle cell homeostasis SOD1;ALDOA GO:0048511| rhythmic process AANAT;HDAC1;PPARG;TP53 GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC4;HDAC1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0007283| spermatogenesis CNR1;SOD1 GO:0046688| response to copper ion SOD1;AANAT GO:0007202| activation of phospholipase C activity AGT;GPR55;HTR2A GO:0010628| positive regulation of gene expression GSN;INS;MT3;CLU;APP;TP53;MDM2;FN1;TRPV4 GO:0010977| negative regulation of neuron projection development TRPV4;APOE;MDM2 GO:0001666| response to hypoxia CYP1A1;CHRNA7;MT3;CAT GO:0002674| negative regulation of acute inflammatory response PPARG;INS;APCS GO:0032460| negative regulation of protein oligomerization OPRD1;INS GO:0031532| actin cytoskeleton reorganization TRPV4;S100A9 GO:0042744| hydrogen peroxide catabolic process HBA1;HBB;APOA4;PRDX1;CAT;GPX1 GO:0045766| positive regulation of angiogenesis C3;C5;CHRNA7;PDCD6;CYP1B1 GO:0001541| ovarian follicle development SOD1 GO:0050714| positive regulation of protein secretion PLA2G1B;FGA GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;MDM2 GO:0030855| epithelial cell differentiation KRT14;PPARG;VDAC1 GO:0000187| activation of MAPK activity TP73;PLA2G1B;APP;CHRNA7;SOD1;C5 GO:0006915| apoptotic process TP73;VDAC1;PDCD6;APLP1;CLU;APP;TP53;SIVA1;MT3;GPX1;S100A8;GSN;S100A9;PARP1 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;APOA1;VDAC1;CACNA1I;TRPV4;TRPV1;CACNA1H;TRPV3;TRPV2 GO:0070374| positive regulation of ERK1 and ERK2 cascade S100A7;APP;ALOX15;TRPV4;FGA;GPR55;HTR2A;OPRM1;HMGCR;MT3;CHRNA7 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0043200| response to amino acid stimulus GLRB;TP53;GLRA3 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0051591| response to cAMP AANAT;NME1 GO:0043085| positive regulation of catalytic activity APOA2;MT3;AGT;SOD1 GO:0007605| sensory perception of sound SOD1;GPX1 GO:0006820| anion transport GLRA1;VDAC1 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;CACNA1H GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;CLU;APP;TRPV1;ESR1;OPRM1;PTGS2;INS;AGT GO:0006936| muscle contraction CACNA1H;UTRN;GLRA1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;APOE;CHRNA7;GPR12;HTR2A GO:0098869| GSR;HBB;HBA1;APOE;CAT;GPX1;PTGS1;PTGS2;S100A9 GO:0006979| response to oxidative stress PRDX1;APOE;APP;TP53;CAT;MT3;KRT1;PTGS1;GPX1;SOD1;PTGS2 GO:0043388| positive regulation of DNA binding NME1;PPARG;MMP9 GO:1901214| CLU;APOE;CHRNA7 GO:0048538| thymus development SOD1 GO:0031100| organ regeneration APOA1;APOA2;PPARG GO:0002376| immune system process CFI;C3;C1QC;C5;C1S;IGHA1;S100A9;C8A;C4BPB;S100A8;IGLV3-21;PGLYRP2;C4BPA;C8G;C4B;IGHM;C1R;C8B;C1QB;CLU;IDO1;CFB;IGKV1-17;FGA;CFH;FCN3 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;INS GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;IDE;APP GO:0006810| transport TRPV2;TTR;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0035025| positive regulation of Rho protein signal transduction GPR55;GPR18;APOA1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT;INS;AGT GO:0015909| long-chain fatty acid transport APOE;PPARG GO:0007568| aging HMGCR;GSN;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;AGT;CAT;TP53;KRT14;KRT16;CYP1A1 GO:0097756| PTGS2;HMGCR;INS GO:0010468| regulation of gene expression TP73;F2;APOE;APP;MDM2;CYP1A2 GO:0030595| leukocyte chemotaxis CNR2;S100A9 GO:0071456| cellular response to hypoxia TP53;MDM2;OPRD1;P4HB;PTGS2;MT3;SLC29A1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;APOE;APOBR;CYP2D6;CYP2C19;APOA1;CYP17A1;CYP3A5;CYP1B1;CYP3A4;HMGCR;CYP3A7;APOL1;CYP1A2 GO:0034605| cellular response to heat PTGS2;PDCD6;TRPV4;TRPV1;TP53 GO:0098815| APP;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;C5;GPR55;HTR1A;CNR1;GPR12;C3;HTR2A;APLP2;AGT;INS;BDKRB1;APOE;APP;PPARG;GPR18;KNG1;F2;APOA1 GO:0042554| superoxide anion generation SOD1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;MDM2 GO:0009611| response to wounding FN1;CYP1A1;F2;GPX1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;ESR1;AGT;CAT 19570:[DB14011 DB06837] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways 19571:[DB14011 DB07962] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0006810| transport ABCC1;CACNA1I;TRPV1;ABCG2;TRPV2;TTR 19572:[DB14011 DB03861] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;OPRM1;OPRD1;KCNMB2;HTR2A;GLRA3 GO:0019228| regulation of action potential in neuron CACNA1G;CACNA1I;CACNA1H;KCNMB2 GO:0008152| metabolic process HEXB;ACAT1;SMPD1 GO:0006811| ion transport GLRA3;CACNA1H;KCNMB2;TRPV3;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1 GO:0065009| regulation of molecular function KCNMB2;TRPV1 GO:0050905| neuromuscular process HEXB;GLRA1;GLRB GO:0001508| regulation of action potential KCNMB2;CACNA1G;GLRA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;HEXB GO:0007626| locomotory behavior SOD1;OPRM1;HEXB GO:0043312| neutrophil degranulation HEXB;CAT;ALOX5 GO:0006687| glycosphingolipid metabolic process SMPD1;HEXB GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;HEXB;CHRNA7;HTR2A;GPR12 GO:0007605| sensory perception of sound HEXB;GPX1;SOD1 19573:[DB14011 DB07714] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes GSR common pathways GO:0006749| glutathione metabolic process GPX1;SOD1;GSR GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0045454| cell redox homeostasis GPX1;GSR GO:0098869| GSR;PTGS2;CAT;PTGS1;GPX1 GO:0055114| oxidation-reduction process GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0034599| cellular response to oxidative stress GSR;CAT;GPX1;SOD1 19574:[DB14011 DB08083] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08083|2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide CA2 common genes common pathways GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG;CA2 GO:0001822| kidney development CAT;CA2 19575:[DB14011 DB01966] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways GO:0043085| positive regulation of catalytic activity SOD1;PSAP GO:0006687| glycosphingolipid metabolic process PSAP;SMPD1 GO:0002576| platelet degranulation SOD1;PSAP GO:0043312| neutrophil degranulation CAT;ALOX5;PSAP GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PSAP;PPARG;CYP1A1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;PSAP GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;PSAP 19576:[DB14011 DB04816] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04816|Dantron ALB common genes common pathways GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;ALB GO:0098869| GPX1;PTGS1;CAT;PTGS2;ALB;GSR GO:0001895| retina homeostasis ALB;SOD1 19577:[DB14011 DB04959] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04959|HspE7 KRT7;UBR4 common genes common pathways GO:0016032| viral reproduction HTR2A;UBR4;KRT7;VDAC1 GO:0043312| neutrophil degranulation UBR4;ALOX5;CAT 19578:[DB14011 DB05076] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05076|Fenretinide RBP4 common genes common pathways GO:0007507| heart development RBP4;PPARG GO:0042572| retinol metabolic process RBP4;CYP1B1 GO:0045471| response to ethanol RBP4;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0007601| visual perception RBP4;GLRA1;CRYZ;GLRB;CYP1B1 GO:0050896| response to stimulus RBP4;TRPM8;TRPA1 GO:0001523| retinoid metabolic process RBP4;NAPEPLD GO:0032526| response to retinoic acid PPARG;RBP4 GO:0030324| lung development RBP4;CYP1A2 GO:0042593| glucose homeostasis TRPV4;PPARG;RBP4;CNR1 19579:[DB14011 DB01893] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01893|N6-Benzyl Adenosine-5'-Diphosphate SRC common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process SRC;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0042542| response to hydrogen peroxide TRPA1;SRC;GPX1;CAT;SOD1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0008283| cell proliferation CYP1A1;GPX1;SRC;HTR1A GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0007165| signal transduction CHRNA7;SRC;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption GPR55;SRC GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT;SRC GO:0016236| macroautophagy VDAC1;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response PPARG;SRC GO:0009615| response to virus CYP1A1;SRC GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;SRC;GPX1;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;SRC;ALOX15;TRPV4 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process IDO1;SRC 19580:[DB14011 DB08660] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08660|1,2,5,8-tetrahydroxyanthracene-9,10-dione CSNK2A1 common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2;GPX1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;CSNK2A1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;CSNK2A1;HTR1A;HTR2A;CHRNA7 GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CSNK2A1 GO:0006915| apoptotic process VDAC1;GPX1;CSNK2A1 GO:0048511| rhythmic process AANAT;CSNK2A1;PPARG 19581:[DB14011 DB05713] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05713|LY-517717 F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 19582:[DB14011 DB00992] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00992|Methyl aminolevulinate FCGR1A common genes common pathways GO:0006955| immune response FCGR1A;OPRD1;CNR2 GO:0007165| signal transduction PPARG;GPR18;SMPD1;FCGR1A;CACNA1I;PLA2G1B;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0045087| innate immune response FCGR1A;PPARG GO:0002376| immune system process IDO1;FCGR1A 19583:[DB14011 DB03994] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03994|Ethanolamine ANXA3 common genes common pathways GO:0045766| positive regulation of angiogenesis ANXA3;CYP1B1;CHRNA7 GO:0031100| organ regeneration ANXA3;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;ANXA3 GO:0070848| response to growth factor stimulus OPRM1;ANXA3 GO:0051384| response to glucocorticoid stimulus ANXA3;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ANXA3;PPARG 19584:[DB14011 DB04400] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0009416| response to light stimulus AANAT;TH GO:0001666| response to hypoxia CAT;CHRNA7;TH;CYP1A1;NOS2 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;TH;OPRD1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;TH;CAT GO:0007605| sensory perception of sound GPX1;TH;SOD1 GO:0055114| oxidation-reduction process PAH;CYP1A1;CYP2C9;NOS2;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;TH;PCBD1;ALOX5;GPX1;PTGS1;CAT GO:0035900| response to isolation stress NAPEPLD;TH GO:0006355| regulation of transcription, DNA-dependent PCBD1;PPARG GO:0042493| response to drug PTGS2;CYP1A2;TH;HTR2A;SOD1;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0006631| fatty acid metabolic process TH;PTGS2;PTGS1;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent PCBD1;PPARG GO:0035094| response to nicotine CHRNA7;TH;CNR1 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0071333| cellular response to glucose stimulus TH;SLC29A1 GO:0032496| response to lipopolysaccharide CNR1;TH;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;NOS2;IDO1 GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0007612| learning TH;PTGS2;VDAC1 GO:0007623| circadian rhythm AANAT;NOS2 GO:0035902| response to immobilization stress TH;CYP1A2;CYP1A1;PPARG GO:0007626| locomotory behavior OPRM1;TH;SOD1 GO:0070848| response to growth factor stimulus OPRM1;TH GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0042755| eating behavior TH;OPRM1;OPRD1 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;TH;CYP1A2;PTGS2;AANAT;ACAT1 GO:0014823| response to activity TH;CAT GO:0051291| protein heterooligomerization PCBD1;GLRB;GLRA1 GO:0010043| response to zinc ion AANAT;TH GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0007613| memory CHRNA7;CNR1;HTR2A;TH;PTGS2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6;TH GO:0007601| visual perception TH;GLRA1;CRYZ;GLRB;CYP1B1 GO:0050890| cognition TH;CHRNA7 GO:0001975| response to amphetamine CNR2;SOD1;TH GO:0043434| response to peptide hormone stimulus TH;TRPV1 GO:0045454| cell redox homeostasis GSR;NOS2;GPX1 GO:0051412| response to corticosterone stimulus AANAT;TH GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0031667| response to nutrient levels SOD1;TH GO:0009635| response to herbicide TH;CYP1A1 GO:0051289| protein homotetramerization CAT;PCBD1;CRYZ;TRPA1;TRPM8;TRPV1 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0045471| response to ethanol CAT;OPRM1;HMGCR;CNR1;SOD1;TH GO:0006351| transcription, DNA-dependent PPARG;PCBD1 GO:0008016| regulation of heart contraction TH;CACNA1H GO:0007507| heart development PPARG;TH GO:0071312| cellular response to alkaloid TH;TRPV1 GO:0008152| metabolic process SMPD1;PAH;ACAT1 GO:0042136| neurotransmitter biosynthetic process PAH;DAGLA;TH 19585:[DB14011 DB01791] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;PDE4D;PDE4A;OPRD1;PDE4C;PDE4B;PPARG;GPR18 GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;PDE4D;HMGCR;CYP1A1 GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B;PDE4D GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction CNR1;GPR12;HTR2A;HTR1A;GPR55;PDE4D;OPRD1;PDE4A;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;PDE4B;PDE4C;CACNA1I;PLA2G1B GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0071320| cellular response to cAMP PDE4D;AANAT 19586:[DB14011 DB00896] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;NR3C1;OPRD1;CNR2;OPRM1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP3A5;CYP1A1 GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0036378| CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;NR3C1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 19587:[DB14011 DB04594] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways GO:0070542| response to fatty acid HMGCL;PTGS2;CAT GO:0007584| response to nutrient HMGCR;HMGCL;CNR1;PPARG GO:0001889| liver development HMGCL;ACAT1;CYP1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;HMGCL;GPX1;NAAA;PTGS1 GO:0051262| protein tetramerization HMGCL;HMGCR;CAT GO:0046951| ketone body biosynthetic process HMGCL;ACAT1 GO:0042594| response to starvation ACAT1;HMGCL;PPARG 19588:[DB14011 DB03645] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways GO:0043403| skeletal muscle tissue regeneration ENO3;GPX1 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ENO3;ABCC1;SMPD1;ABCG2 GO:0007568| aging ENO3;CYP1A1;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CAT 19589:[DB14011 DB02581] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways GO:0002376| immune system process IL2;IDO1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;IL2;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0050728| negative regulation of inflammatory response CNR2;IL2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IL2;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;IL2 GO:0007155| cell adhesion CYP1B1;IL2 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0050729| positive regulation of inflammatory response TRPV4;IL2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;IL2;TRPV4;TRPV1 GO:0006955| immune response IL2;CNR2;OPRD1 GO:0030217| T cell differentiation IL2;GPR18 GO:0001934| positive regulation of protein phosphorylation IL2;CHRNA7 GO:0045471| response to ethanol CAT;SOD1;CNR1;OPRM1;HMGCR;IL2 19590:[DB14011 DB06599] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06599|Lexatumumab TNFRSF10B common genes common pathways GO:0006915| apoptotic process GPX1;TNFRSF10B;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;TNFRSF10B;PTGS2 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;CYP1A2;OPRM1;TNFRSF10B;CNR1;IDO1;CYP1A1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;CNR1;TNFRSF10B;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7 GO:1902042| GPX1;TNFRSF10B GO:0034976| response to endoplasmic reticulum stress ALOX15;TNFRSF10B GO:0006919| activation of caspase activity PPARG;TNFRSF10B GO:0071260| cellular response to mechanical stimulus TNFRSF10B;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;TNFRSF10B GO:0006955| immune response TNFRSF10B;OPRD1;CNR2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS2;CNR2;TNFRSF10B;PTGS1;ALOX5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;TNFRSF10B;PTGS2 19591:[DB14011 DB05552] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05552|TG100-115 PIK3CD;PIK3CG common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;PIK3CG GO:0007165| signal transduction PIK3CD;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7 GO:0014065| phosphatidylinositol 3-kinase cascade PIK3CD;PIK3CG;HTR2A GO:0001525| angiogenesis PTGS2;CYP1B1;PIK3CG GO:0071320| cellular response to cAMP AANAT;PIK3CG GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;PIK3CG;PIK3CD;IDO1;ALOX15;TRPV1 GO:0030217| T cell differentiation PIK3CD;GPR18 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;PIK3CG;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0043085| positive regulation of catalytic activity PIK3CG;SOD1 GO:0002376| immune system process PIK3CG;PIK3CD;IDO1 GO:0043406| positive regulation of MAP kinase activity PIK3CG;HTR2A GO:0010628| positive regulation of gene expression PIK3CD;TRPV4 GO:0045087| innate immune response PIK3CD;PIK3CG;PPARG GO:0030593| neutrophil chemotaxis PIK3CG;PIK3CD;PLA2G1B GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CG;PIK3CD;GPX1 19592:[DB14011 DB07224] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07224|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB GO:0030855| epithelial cell differentiation PPARG;CTSB;VDAC1 GO:0043312| neutrophil degranulation CTSB;ALOX5;CAT GO:0046718| entry of virus into host cell CTSB;HTR2A 19593:[DB14011 DB07148] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07148|(6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one PREP common genes common pathways 19594:[DB14011 DB03132] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03132|3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid TPI1 common genes common pathways GO:0008152| metabolic process TPI1;ACAT1;SMPD1 19595:[DB14011 DB05471] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;NFKB1;CAT GO:0045087| innate immune response PPARG;NFKB2;NFKB1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;PPARG;NFKB2;TRPV1;TRPV4 GO:0034097| response to cytokine stimulus NFKB2;AANAT;PTGS2 GO:0043066| negative regulation of apoptotic process CAT;NFKB1;GPX1;SOD1;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;PLA2G1B;PPARG;NFKB2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;NFKB2;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0050728| negative regulation of inflammatory response CNR2;NFKB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NFKB1 GO:0006355| regulation of transcription, DNA-dependent NFKB2;PPARG;NFKB1 GO:0007568| aging NFKB2;CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:0045892| negative regulation of transcription, DNA-dependent NFKB1;PPARG GO:0048511| rhythmic process AANAT;NFKB2;PPARG GO:0071356| cellular response to tumor necrosis factor TRPV1;NFKB1 GO:0006915| apoptotic process GPX1;NFKB1;VDAC1 GO:0071260| cellular response to mechanical stimulus NFKB1;PTGS2 GO:0006351| transcription, DNA-dependent NFKB2;PPARG;NFKB1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NFKB1 GO:0006954| inflammatory response NFKB1;ALOX5;PTGS1;CNR2;PTGS2;IDO1;ALOX15;TRPV1;NFKB2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;NFKB2;NFKB1;CAT GO:0010629| negative regulation of gene expression OPRD1;NFKB1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;NFKB2;CHRNA7;NFKB1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A 19596:[DB14011 DB06870] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;AR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV1;TRPV4 GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport TRPV2;AR;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0007283| spermatogenesis AR;SOD1;CNR1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006351| transcription, DNA-dependent AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;AR GO:0008283| cell proliferation CYP1A1;AR;GPX1;HTR1A GO:0007548| sex differentiation AR;CYP17A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 19597:[DB14011 DB07395] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways GO:0042593| glucose homeostasis CNR1;PPARG;PYGL;TRPV4 GO:0043312| neutrophil degranulation PYGL;CAT;ALOX5 GO:0008152| metabolic process ACAT1;PYGL;SMPD1 19598:[DB14011 DB08119] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 19599:[DB14011 DB07072] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CYP1A1;DPP4;CHRNA7;CAT GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 19600:[DB14011 DB06705] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06705|Gadofosveset trisodium ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT 19601:[DB14011 DB01640] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways GO:0007165| signal transduction CHRNA7;PDE3B;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0032869| cellular response to insulin stimulus PDE3B;PPARG;PLA2G1B GO:0001525| angiogenesis CYP1B1;PTGS2;PDE3B GO:0043951| negative regulation of cAMP-mediated signaling PDE3B;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;PDE3B;PPARG;GPR18 GO:0016525| negative regulation of angiogenesis PDE3B;PPARG GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1;PDE3B 19602:[DB14011 DB02762] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02762|RU79072 SRC common genes common pathways GO:0031667| response to nutrient levels SRC;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;SRC;PTGS2;CNR1;SOD1 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;SRC;TRPA1 GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;SRC GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0045453| bone resorption GPR55;SRC GO:0070542| response to fatty acid PTGS2;CAT;SRC GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;SRC;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;SRC;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0016236| macroautophagy VDAC1;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0043066| negative regulation of apoptotic process CAT;SRC;GPX1;SOD1;PTGS2;HMGCR GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0009615| response to virus CYP1A1;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;SRC;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0002376| immune system process SRC;IDO1 19603:[DB14011 DB04136] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04136|Lysophosphotidylserine F2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;F2 GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 19604:[DB14011 DB07494] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07494|(3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE CHRFAM7A common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;CHRFAM7A;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0006811| ion transport CHRNA7;TRPV2;CHRFAM7A;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;GLRA1;TRPA1;CACNA1G GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;CHRNA7;CHRFAM7A;GLRA3 19605:[DB14011 DB02988] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02988|Imino-Tryptophan DAO common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;CYP3A5;ALOX15;DAO;CYP2D6;CYP2C19;IDO1;GSR;CYP1A1;CYP2C9;CRYZ;ALOX5;PTGS1;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 19606:[DB14011 DB05708] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes CHRNA7;CYP1A2 common pathways GO:0098815| CHRNA7 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CHRNA7;TRPV4;TRPM8 GO:1901214| CHRNA7 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0095500| CHRNA7 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;GLRB;TRPV1;TRPA1;GLRA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;ALOX15 GO:1905920| CHRNA7 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0140059| CHRNA7 GO:0010193| response to ozone CAT;CYP2E1 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7 GO:1902991| CHRNA7 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0007611| learning or memory CNR1;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0007614| short-term memory CHRNA7 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:1905144| CHRNA7 GO:1905906| CHRNA7 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP2E1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042493| response to drug CAT;SOD1;HTR2A;CYP2E1;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;CYP2E1;HMGCR;CYP3A7;PTGS2;CYP1A2 GO:0050808| synapse organization CHRNA7 GO:0010243| response to organic nitrogen TRPV1;PTGS2;CYP2E1 GO:0050893| sensory processing CHRNA7 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0035094| response to nicotine CNR1;CHRNA7 GO:0050890| cognition CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0070588| calcium ion transmembrane transport TRPV3;OPRM1;CACNA1H;TRPV2;CHRNA7;CACNA1G;TRPA1;CACNA1I;TRPV4;TRPV1;TRPM8 GO:1904645| CHRNA7 GO:1900273| CHRNA7 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0045471| response to ethanol CAT;CYP2E1;SOD1;CNR1;OPRM1;HMGCR GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0060078| regulation of postsynaptic membrane potential CHRNA7 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902430| CHRNA7 GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;TRPV3;CACNA1H;CHRNA7;TRPV2 19607:[DB14011 DB08843] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08843|GS 0573 SLC22A6 common genes common pathways GO:0098656| SLC22A6;VDAC1 GO:0051260| protein homooligomerization SLC22A6;GLRA1;GLRA3;ACAT1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;SLC22A6;CACNA1G;ABCC1;TRPA1 19608:[DB14011 DB07613] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways GO:0019371| cyclooxygenase pathway PTGS2;HPGDS;PTGS1 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;HPGDS;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0006693| prostaglandin metabolic process PTGS1;HPGDS;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS;PTGS1 GO:0007165| signal transduction CHRNA7;HPGDS;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0006633| fatty acid biosynthetic process PTGS1;HPGDS;PTGS2;PLA2G1B GO:0006631| fatty acid metabolic process PTGS2;HPGDS;PTGS1;ALOX15 GO:0007626| locomotory behavior HPGDS;SOD1;OPRM1 19609:[DB14011 DB07261] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07261|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 19610:[DB14011 DB06849] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways 19611:[DB14011 DB00616] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00616|Candoxatril MME;ACE common genes common pathways GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;ACE;PPARG GO:0071345| cellular response to cytokine stimulus MME;TRPV1 GO:0060047| heart contraction GPX1;ACE;SOD1 GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0019233| sensory perception of pain CNR1;HTR2A;PTGS2;CNR2;OPRM1;MME;OPRD1;TRPV1;TRPA1 GO:0007283| spermatogenesis CNR1;SOD1;ACE GO:0002446| neutrophil mediated immunity PLA2G1B;ACE GO:0001822| kidney development ACE;CAT;MME GO:0043312| neutrophil degranulation ALOX5;CAT;MME 19612:[DB14011 DB06147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06147|Sulfathiazole CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP19A1;CYP1A1;CYP2C9;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;CYP19A1 GO:0006694| steroid biosynthetic process CYP19A1;CYP17A1;HMGCR GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP19A1 19613:[DB14011 DB02950] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02950|Hymenialdisine CDK5;CDK1;CDK2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;CDK1;ACAT1;AANAT;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;CDK1 GO:0008283| cell proliferation GPX1;CDK1;HTR1A;CDK5;CYP1A1 GO:0014823| response to activity CAT;CDK1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;CDK1 GO:0045740| positive regulation of DNA replication CDK1;PLA2G1B GO:0051966| regulation of synaptic transmission, glutamatergic CDK5;CNR1 GO:0046718| entry of virus into host cell HTR2A;CDK1 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CACNA1I;CDK5;CACNA1G GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;GLRB;VDAC1;GLRA1;CDK5;CACNA1G GO:0008542| visual learning CDK5;HMGCR GO:0019233| sensory perception of pain OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPV1;TRPA1;CDK5 GO:0048678| response to axon injury CDK1;SOD1 GO:0045471| response to ethanol CAT;OPRM1;CDK1;HMGCR;CNR1;SOD1 GO:0060078| regulation of postsynaptic membrane potential CDK5;CHRNA7 GO:0007399| nervous system development CDK5;SMPD1;GLRB GO:0048148| behavioral response to cocaine CDK5;HTR2A GO:0042542| response to hydrogen peroxide TRPA1;CDK1;SOD1;GPX1;CAT GO:0006915| apoptotic process GPX1;CDK1;VDAC1;CDK5 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;CDK5 GO:0030855| epithelial cell differentiation CDK1;VDAC1;PPARG GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CDK1;CHRNA7 GO:0046686| response to cadmium ion CAT;CDK1 GO:0045892| negative regulation of transcription, DNA-dependent CDK5;PPARG GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;CDK2;TRPA1 GO:0048511| rhythmic process CDK5;PPARG;AANAT GO:0046688| response to copper ion SOD1;CDK1;AANAT GO:0010628| positive regulation of gene expression TRPV4;CDK1 GO:0010468| regulation of gene expression CYP1A2;CDK1 GO:0009611| response to wounding CDK5;CYP1A1;GPX1 GO:0031100| organ regeneration PPARG;CDK1 GO:0007569| cell aging CDK1;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG GO:0042493| response to drug CAT;SOD1;HTR2A;CDK1;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1 GO:0006367| transcription initiation from RNA polymerase II promoter CDK1;PPARG GO:0010243| response to organic nitrogen TRPV1;PTGS2;CDK1 GO:0070509| calcium ion import CACNA1H;CDK5;CACNA1G;TRPV4;CACNA1I GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;CDK5;GLRA1;TRPV1;GLRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;CDK2;PPARG GO:0045786| negative regulation of cell cycle CDK5;PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;CDK1;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;CDK2 19614:[DB14011 DB01662] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process CTRB1;ABCC1 19615:[DB14011 DB07350] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;HDAC8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;HDAC8 GO:0010629| negative regulation of gene expression OPRD1;HDAC8 GO:0006351| transcription, DNA-dependent HDAC8;PPARG 19616:[DB14011 DB07849] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways GO:0031667| response to nutrient levels GSTP1;SOD1 GO:1904706| PPARG;GSTP1 GO:0045471| response to ethanol GSTP1;OPRM1;HMGCR;SOD1;CNR1;CAT GO:0008152| metabolic process ACAT1;SMPD1;GSTP1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;GSTP1;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0009636| response to toxin GSTP1;CYP1B1;CYP1A1;GPX1;CAT GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0006749| glutathione metabolic process GSR;GSTP1;GPX1;SOD1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B GO:0000302| response to reactive oxygen species GSTP1;SOD1;CAT;GPX1 GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;GSR;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0043312| neutrophil degranulation GSTP1;CAT;ALOX5 GO:0043200| response to amino acid stimulus GLRB;GSTP1;GLRA3 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0043407| negative regulation of MAP kinase activity SMPD1;GSTP1;HMGCR GO:0032355| response to estradiol stimulus GSTP1;PTGS2;CYP1A2;CAT GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR;GSTP1 19617:[DB14011 DB03297] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03297|Benzylsulfinic Acid HPN;SOD2;CMA1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;SOD2;CYP1B1 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;SOD2;PPARG GO:0050727| regulation of inflammatory response PTGS2;CMA1 GO:0000303| response to superoxide SOD2;SOD1 GO:0006357| regulation of transcription from RNA polymerase II promoter SOD2;PPARG GO:0019430| removal of superoxide radicals SOD2;SOD1 GO:0051289| protein homotetramerization CAT;CRYZ;TRPA1;TRPV1;SOD2;TRPM8 GO:0043524| negative regulation of neuron apoptosis SOD2;SOD1 GO:0010628| positive regulation of gene expression HPN;TRPV4 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;CMA1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;HPN;SOD1;GPX1;CAT GO:0035722| interleukin-12-mediated signaling pathway SOD1;SOD2 GO:0071333| cellular response to glucose stimulus SLC29A1;CMA1 GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;SOD2;GSR GO:0006801| superoxide metabolic process SOD2;SOD1 GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;SOD2;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:1902176| GPX1;SOD2 19618:[DB14011 DB00264] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes CYP2C19;CYP2D6 common pathways GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;SLC22A2;TRPV1;TRPV4;ABCB1;CACNA1I;VDAC1;TRPA1;CACNA1G;ABCC1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCB1;ABCG2;TRPV2 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;GPR12;CNR1;ADRB2;OPRM1;CNR2;OPRD1;ADRB1;PPARG;GPR18 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;DAGLA;CYP2D6;ALOX15;CYP1B1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;PTGS1;ALOX5;GPX1 GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;ABCB1;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ADRB2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0002024| diet induced thermogenesis ADRB2;TRPV4;ADRB1;TRPV1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0006812| cation transport TRPM8;SLC22A2 GO:0006855| drug transmembrane transport ABCG2;SLC22A2;ABCB1;ABCC1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006811| ion transport TRPM8;SLC22A2;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0007165| signal transduction CACNA1I;ADRB1;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;ADRB2 GO:0045453| bone resorption GPR55;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;NAAA;GPX1;PTGS1 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1;ADRB1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0009409| response to cold ADRB1;TRPM8;TRPA1;PPARG;ADRB2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;ADRB2 GO:0050873| brown fat cell differentiation ADRB1;ADRB2;PTGS2 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 19619:[DB14011 DB12865] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12865|Etelcalcetide CASR common genes common pathways GO:0051592| response to calcium ion AANAT;CASR GO:0001503| ossification ALOX15;CASR GO:0006816| calcium ion transport TRPV2;CHRNA7;CASR;TRPV3;CACNA1H;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1 GO:0051924| regulation of calcium ion transport OPRD1;CASR GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway CASR;OPRM1;OPRD1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;CASR GO:0007165| signal transduction CASR;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;CASR;ACAT1;AANAT GO:0090280| positive regulation of calcium ion import CASR;TRPV2;TRPV3 GO:0070509| calcium ion import CACNA1I;TRPV4;CACNA1G;CASR;CACNA1H GO:0071333| cellular response to glucose stimulus CASR;SLC29A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;CASR GO:0042311| vasodilation CASR;GPX1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CASR;CHRNA7 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;CASR GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CASR GO:0007635| chemosensory behavior TRPV1;CASR GO:0071456| cellular response to hypoxia SLC29A1;CASR;PTGS2;OPRD1 GO:0006874| cellular calcium ion homeostasis CHRNA7;CASR;HTR2A;GPR12;TRPM8;TRPV4 GO:0006915| apoptotic process GPX1;CASR;VDAC1 GO:0010628| positive regulation of gene expression CASR;TRPV4 19620:[DB14011 DB07007] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide NOS2;CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0007623| circadian rhythm AANAT;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP2C9;CYP1A1;CRYZ;NOS2;ALOX5;PTGS1;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B 19621:[DB14011 DB09536] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09536|Titanium dioxide MARCO common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;MARCO;CHRNA7;ALOX15;TRPV4 GO:0043277| apoptotic cell clearance MARCO;ALOX15 GO:0002376| immune system process MARCO;IDO1 GO:0045087| innate immune response MARCO;PPARG GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;MARCO GO:0001934| positive regulation of protein phosphorylation MARCO;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;MARCO 19622:[DB14011 DB03531] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03531|Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone DAO common genes common pathways GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;DAO;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ 19623:[DB14011 DB05253] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05253|Proellex PGR common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PGR;PPARG GO:0006351| transcription, DNA-dependent PPARG;PGR GO:0010629| negative regulation of gene expression OPRD1;PGR GO:0007165| signal transduction PLA2G1B;PGR;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PGR GO:0006355| regulation of transcription, DNA-dependent PPARG;PGR GO:0006367| transcription initiation from RNA polymerase II promoter PGR;PPARG 19624:[DB14011 DB04418] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways GO:0042594| response to starvation ACAT1;PPARG;ADSSL1 GO:0002376| immune system process ADSSL1;IDO1 19625:[DB14011 DB00523] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation RARB;RARA;RARG;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRB;RXRA;RXRG;PLA2G1B;RARB;RARG;RARA GO:0071300| cellular response to retinoic acid PPARG;RARG;RARA GO:0043066| negative regulation of apoptotic process RARA;GPX1;RARG;CAT;HMGCR;PTGS2;SOD1;RARB GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARA;RARG;TRPV4;TRPV1;RARB;PPARG;RXRA GO:0034097| response to cytokine stimulus PTGS2;RARA;AANAT GO:0008203| cholesterol metabolic process RXRA;CAT;HMGCR GO:0032526| response to retinoic acid RXRA;PPARG;RARG;RARA GO:0006367| transcription initiation from RNA polymerase II promoter RARG;RARA;PPARG;RXRB;RXRA;RXRG;RARB GO:0033189| response to vitamin A CYP1A1;PPARG;RARA;CAT GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1 GO:0006355| regulation of transcription, DNA-dependent RXRB;RXRA;PPARG;RXRG;RARB;RARG;RARA;CRABP2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG;RARA GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP26C1;CRYZ;CYP2C9;CYP1A1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;RARA;GPR18 GO:0032355| response to estradiol stimulus RARA;CAT;PTGS2;CYP1A2 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0006810| transport ABCB1;CACNA1I;TRPV1;ABCG2;ABCC1;TRPV2 GO:0001657| ureteric bud development RARA;CAT;RARB GO:0010628| positive regulation of gene expression RARG;RARA;TRPV4 GO:0007283| spermatogenesis CNR1;SOD1;RARA GO:0043277| apoptotic cell clearance ALOX15;RARA GO:0045892| negative regulation of transcription, DNA-dependent RARA;PPARG GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;ABCC1;TRPA1;VDAC1;CACNA1I;ABCB1;TRPV4;TRPV1;ABCG2;TRPM8 GO:0006915| apoptotic process VDAC1;GPX1;IGFBP3 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;RARB;IDO1;SMPD1;PPARG;IGFBP3;RARG;PTGS2;SOD1;CNR1 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP26C1 GO:0007507| heart development PPARG;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;RARA;CAT GO:0043401| steroid hormone mediated signaling pathway RARA;RARG;RXRA;RXRB;PPARG;RARB;RXRG GO:0006351| transcription, DNA-dependent RARB;RXRG;RXRB;RXRA;PPARG;RARA;RARG GO:0001889| liver development ACAT1;RARA;CYP1A1 GO:0051289| protein homotetramerization TRPV1;RXRG;TRPM8;RXRA;TRPA1;CRYZ;CAT GO:0016032| viral reproduction HTR2A;VDAC1;RXRA GO:0010629| negative regulation of gene expression RARA;OPRD1 GO:0007565| female pregnancy IDO1;PSG5;RARA GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IGFBP3 GO:0043010| camera-type eye development CYP1A1;RXRA;RARG GO:0007165| signal transduction PLA2G1B;CACNA1I;RARB;PPARG;GPR18;SMPD1;CHRNA7;CRABP2;RARA;GPR55;HTR1A;CRABP1;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0007566| embryo implantation PTGS2;SOD1;RXRA GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1;RXRA GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0022008| neurogenesis RARB;DAGLA GO:0001649| osteoblast differentiation CAT;IGFBP3 GO:0001890| placenta development SOD1;RXRA;PPARG GO:0008285| negative regulation of cell proliferation PPARG;RARB;CYP1B1;OPRM1;PTGS2;RARA;IGFBP3;RARG GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 19626:[DB14011 DB00259] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes CYP2C19;CYP3A4;CYP2D6 common pathways GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0036378| CYP3A4 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0010193| response to ozone CYP2E1;CAT GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;CYP2E1;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP2E1;CYP1A2;PTGS2;CAT GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;FAAH GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0097267| CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0006641| triglyceride metabolic process GPX1;CAT;CYP2E1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0045471| response to ethanol CAT;CYP2E1;CNR1;SOD1;OPRM1;HMGCR GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;CYP2C9;PPARG;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 19627:[DB14011 DB00288] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes CYP3A4 common pathways GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0031532| actin cytoskeleton reorganization ANXA1;TRPV4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1;ANXA1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;ANXA1 GO:0007186| G-protein coupled receptor signaling pathway ANXA1;PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0002376| immune system process IDO1;ANXA1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP2C9;CYP1A1 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;ANXA1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ANXA1 GO:0045087| innate immune response PPARG;ANXA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;NR3C1 GO:0043066| negative regulation of apoptotic process ANXA1;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;PLA2G1B GO:0031394| positive regulation of prostaglandin biosynthetic process ANXA1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG;ANXA1 GO:0070365| hepatocyte differentiation CYP1A1;ANXA1 GO:0046883| regulation of hormone secretion HTR2A;HTR1A;ANXA1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ANXA1 GO:0043434| response to peptide hormone stimulus TRPV1;ANXA1 GO:1900087| ANXA1;CYP1A1 GO:0051384| response to glucocorticoid stimulus ANXA1;PTGS2 GO:0007165| signal transduction NR3C1;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;ANXA1 GO:0009725| response to hormone stimulus ANXA1;ACAT1 GO:0050482| arachidonic acid secretion ANXA1;PLA2G1B GO:0044849| OPRM1;ANXA1 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ANXA1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;IDO1;ALOX15;ANXA1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0007166| cell surface receptor linked signaling pathway ANXA1;TRPV1;TRPA1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0050727| regulation of inflammatory response ANXA1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;ANXA1;IDO1;SMPD1;PPARG 19628:[DB14011 DB03623] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03623|9-(4-Hydroxyphenyl)-2,7-Phenanthroline MAPK10 common genes common pathways GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;MAPK10;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0042752| regulation of circadian rhythm PPARG;MAPK10 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;MAPK10 GO:0048511| rhythmic process PPARG;MAPK10;AANAT GO:0009416| response to light stimulus AANAT;MAPK10 GO:0010468| regulation of gene expression MAPK10;CYP1A2 19629:[DB14011 DB08674] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08674|(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;FNTB;PTGS2 19630:[DB14011 DB00156] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways GO:0055085| transmembrane transport CACNA1H;SLC16A10;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1 19631:[DB14011 DB03095] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03095|Tetramethylammonium Ion GALE common genes common pathways 19632:[DB14011 DB13503] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13503|Tyrothricin ACHE common genes common pathways GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion ACHE;CYP1B1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0009611| response to wounding GPX1;ACHE;CYP1A1 19633:[DB14011 DB09279] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09279|Fimasartan AGTR1 common genes common pathways GO:0060326| cell chemotaxis ABCC1;AGTR1 GO:0001822| kidney development AGTR1;CAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;AGTR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;AGTR1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;AGTR1;GPR55 GO:0007186| G-protein coupled receptor signaling pathway AGTR1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;AGTR1;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0007204| elevation of cytosolic calcium ion concentration AGTR1;OPRM1;HTR2A;TRPV4;TRPV1 GO:0050729| positive regulation of inflammatory response AGTR1;TRPV4 19634:[DB14011 DB03124] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;CASP3;AANAT;ACAT1 GO:0009411| response to UV CAT;CASP3 GO:0006919| activation of caspase activity CASP3;PPARG GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0042542| response to hydrogen peroxide SOD1;CASP3;GPX1;CAT;TRPA1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;CASP3;PTGS2;SOD1;CNR1 GO:0035556| intracellular signal transduction PLA2G1B;CASP3 GO:0045165| cell fate commitment PPARG;CASP3 GO:0007507| heart development CASP3;PPARG GO:0043200| response to amino acid stimulus GLRB;CASP3;GLRA3 GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0006915| apoptotic process VDAC1;CASP3;GPX1 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;CASP3 GO:0010033| response to organic substance CASP3;CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CASP3;CAT GO:0009611| response to wounding CYP1A1;CASP3;GPX1 GO:0007605| sensory perception of sound SOD1;CASP3;GPX1 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;CASP3;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;CASP3 GO:0035094| response to nicotine CHRNA7;CASP3;CNR1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CASP3;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0042060| wound healing ALOX15;OPRM1;CASP3 GO:0007611| learning or memory CASP3;CHRNA7;CNR1 GO:0046677| response to antibiotic CASP3;SOD1;CYP1A1 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CASP3;CAT 19635:[DB14011 DB08626] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08626|Thiorphan MME common genes common pathways GO:0071345| cellular response to cytokine stimulus TRPV1;MME GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;PTGS2;CNR2;OPRM1;MME;CNR1;HTR2A GO:0001822| kidney development CAT;MME GO:0043312| neutrophil degranulation MME;ALOX5;CAT 19636:[DB14011 DB05115] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05115|NN344 INSR common genes common pathways GO:0045740| positive regulation of DNA replication PLA2G1B;INSR GO:0032869| cellular response to insulin stimulus PLA2G1B;INSR;PPARG GO:0007613| memory INSR;CNR1;HTR2A;PTGS2;CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7;INSR GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0035556| intracellular signal transduction PLA2G1B;INSR GO:0000187| activation of MAPK activity INSR;PLA2G1B;SOD1;CHRNA7 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;INSR GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;INSR;PPARG;GPR18 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;INSR;PTGS2;OPRM1 GO:0042593| glucose homeostasis CNR1;INSR;PPARG;TRPV4 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;INSR GO:0006355| regulation of transcription, DNA-dependent INSR;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0007612| learning PTGS2;INSR;VDAC1 GO:0008284| positive regulation of cell proliferation INSR;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 19637:[DB14011 DB08345] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08345|4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0006915| apoptotic process GPX1;CSNK2A1;VDAC1 GO:0048511| rhythmic process AANAT;CSNK2A1;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;CSNK2A1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0007165| signal transduction CSNK2A1;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B 19638:[DB14011 DB06042] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways GO:0048511| rhythmic process TOP2A;PPARG;AANAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0043312| neutrophil degranulation CAT;ALOX5;TUBB GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0043065| positive regulation of apoptotic process PPARG;TOP2A;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 19639:[DB14011 DB01832] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01832|4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid FAH common genes common pathways GO:0008152| metabolic process FAH;ACAT1;SMPD1 19640:[DB14011 DB03425] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways GO:0006811| ion transport CHRNA7;TRPV2;GRIK2;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GLRA1;TRPA1;CACNA1G GO:0001662| behavioral fear response VDAC1;HTR1A;GRIK2 GO:0019228| regulation of action potential in neuron CACNA1H;GRIK2;CACNA1G;CACNA1I GO:0007268| synaptic transmission OPRD1;OPRM1;GLRA3;HTR2A;GRIK2;CACNA1G;GLRA1;GLRB;VDAC1 GO:0043524| negative regulation of neuron apoptosis SOD1;GRIK2 GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;TRPV2;GRIK2 GO:0006874| cellular calcium ion homeostasis GRIK2;GPR12;HTR2A;CHRNA7;TRPM8;TRPV4 GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;CACNA1H;GRIK2 GO:0034220| ion transmembrane transport GRIK2;GLRA3;CHRNA7;TRPA1;GLRA1;TRPV1;GLRB GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1H;TRPV3;GRIK2;TRPV2 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;GRIK2 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GRIK2;GLRA3;TRPV1;GLRB;GLRA1 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;GRIK2 19641:[DB14011 DB07809] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07809|4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE F2 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 19642:[DB14011 DB08060] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways GO:0051591| response to cAMP AGXT;AANAT GO:0051384| response to glucocorticoid stimulus PTGS2;AGXT 19643:[DB14011 DB05264] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05264|NPI 32101 CSF2RB common genes common pathways GO:0032496| response to lipopolysaccharide CSF2RB;CYP1A1;IDO1;CNR1;OPRM1;CYP1A2;PTGS2;CNR2 GO:0065009| regulation of molecular function CSF2RB;TRPV1 GO:0007165| signal transduction PPARG;CSF2RB;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 19644:[DB14011 DB01742] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways GO:0016032| viral reproduction HTR2A;PPIA;VDAC1 GO:0043312| neutrophil degranulation PPIA;CAT;ALOX5 GO:0035722| interleukin-12-mediated signaling pathway PPIA;SOD1 GO:0050714| positive regulation of protein secretion PLA2G1B;PPIA 19645:[DB14011 DB00750] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00750|Prilocaine SCN5A common genes common pathways GO:0086002| SCN5A;CACNA1G GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;SCN5A;ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCG2 GO:0086015| SCN5A;CACNA1G GO:0086016| CACNA1G;SCN5A GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN5A GO:0086046| CACNA1G;SCN5A GO:0006811| ion transport TRPV2;CHRNA7;SCN5A;TRPV3;CACNA1H;GLRA3;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0086045| CACNA1G;SCN5A GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0086010| CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0002027| regulation of heart rate SCN5A;CACNA1G GO:0086091| SCN5A;CACNA1G GO:0071277| cellular response to calcium ion ALOX15;SCN5A GO:0019228| regulation of action potential in neuron SCN5A;CACNA1H;CACNA1I;CACNA1G GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;SCN5A 19646:[DB14011 DB05849] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05849|NCX 950 ADRB2 common genes common pathways GO:0002024| diet induced thermogenesis ADRB2;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PPARG;PLA2G1B GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0007186| G-protein coupled receptor signaling pathway ADRB2;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPA1;TRPV1 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0009409| response to cold ADRB2;PPARG;TRPA1;TRPM8 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB2;CNR1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;ADRB2;HTR1A;GPR55 GO:0045453| bone resorption GPR55;ADRB2 19647:[DB14011 DB03470] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03470|Trypanothione TPR common genes common pathways GO:0034605| cellular response to heat TPR;PTGS2;TRPV4;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;TRPV1;TRPV4;PPARG GO:0016032| viral reproduction TPR;HTR2A;VDAC1 GO:0042307| positive regulation of protein import into nucleus TPR;PTGS2 19648:[DB14011 DB02541] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02541|4-Hydroxybutan-1-Aminium PRSS3 common genes common pathways GO:0009235| cobalamin metabolic process PRSS3;ABCC1 GO:0043542| endothelial cell migration CYP1B1;PRSS3 GO:0043312| neutrophil degranulation PRSS3;ALOX5;CAT 19649:[DB14011 DB08510] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08510|5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0002376| immune system process IDO1;IGHG2 GO:0045087| innate immune response IGHG2;PPARG 19650:[DB14011 DB04445] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;SULT2A1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;SULT2A1;CYP1A1;PPARG GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4;SULT2A1 GO:0016042| lipid catabolic process PLA2G1B;DAGLA;NAPEPLD;SULT2A1 19651:[DB14011 DB07964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07964|(3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;ADAM17 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;CYP1A1;ADAM17;PPARG;TRPA1;ABCG2 GO:0050830| defense response to Gram-positive bacterium ADAM17;PLA2G1B GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;ADAM17 GO:0007155| cell adhesion ADAM17;CYP1B1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;ADAM17;CYP1A1;IDO1 GO:0001666| response to hypoxia CYP1A1;ADAM17;CAT;CHRNA7 GO:0002446| neutrophil mediated immunity PLA2G1B;ADAM17 19652:[DB14011 DB04133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0055085| transmembrane transport SLC22A5;SLC22A8;CACNA1H;TRPV3;SLC22A11;TRPV2;TRPA1;SLC22A6;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4 GO:0046415| urate metabolic process SLC22A11;ABCG2 GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A5 GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport GLRA3;SLC22A5;SLC22A8;CACNA1H;TRPV3;CHRNA7;SLC22A11;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1 19653:[DB14011 DB04934] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04934|Rifalazil rpoB;CYP3A4 common genes CYP3A4 common pathways GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0002933| CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0036378| CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 19654:[DB14011 DB00751] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes HTR2A;CYP2D6;CYP3A4 common pathways GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A GO:0019369| arachidonic acid metabolic process ALOX15;DAGLA;CYP2D6;CYP1B1;FAAH GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2A GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CYP2B6;CRYZ;CYP1A1;CYP2C9 GO:0044380| protein localization to cytoskeleton HTR2A GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug ADRA1A;ABCB1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0050795| regulation of behavior HTR2A;HTR1A GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2B6;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;ADRA2A GO:0014824| artery smooth muscle contraction HTR2A GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRM1;OPRD1;HRH1;HTR2A GO:0007623| circadian rhythm HTR7;AANAT GO:0014059| regulation of dopamine secretion HTR2A GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR7;OPRD1;CNR2;OPRM1;HRH2;CNR1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;ADRA1A GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008219| cell death HTR2A GO:0006915| apoptotic process ADRA1A;VDAC1;GPX1 GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV1;ABCB1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;ADRA1A;TRPV4 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2B6;CYP2D6;CYP2C19 GO:0007210| serotonin receptor signaling pathway HTR2A;HTR1A GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CHRNA7;TRPV4;TRPM8 GO:0042593| glucose homeostasis ADRA2A;TRPV4;PPARG;CNR1 GO:0006810| transport TRPV1;CACNA1I;ABCB1;ABCG2;ABCC1;TRPV2 GO:0007568| aging CYP1A1;ADRA1A;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP2B6;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;HRH2;GPR55;HTR1A;OPRD1;HRH1;OPRM1;CNR2;GPR18;PPARG;ADRA2A;HTR7;ADRA1A GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;TRPA1 GO:0048565| digestive tract development HRH2;CYP1A1 GO:0008542| visual learning HMGCR;HRH1;HRH2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0033674| positive regulation of kinase activity HTR2A GO:0016032| viral reproduction HTR2A;VDAC1 GO:0006955| immune response HRH2;OPRD1;CNR2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PTGS1;ALOX5;HRH1;PTGS2;CNR2 GO:0008209| androgen metabolic process CYP3A4 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;TRPA1 GO:0007268| synaptic transmission GLRB;VDAC1;HTR7;GLRA1;CACNA1G;GLRA3;HTR2A;OPRM1;OPRD1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0048148| behavioral response to cocaine HTR2A GO:0035556| intracellular signal transduction ADRA1A;PLA2G1B GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2B6;CYP2C9 GO:0042310| vasoconstriction HTR1A;HTR7 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A GO:0001659| temperature homeostasis HTR2A;GPX1;TRPV1 GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1;TRPV1;TRPA1 GO:0051100| negative regulation of binding CYP2D6 GO:0030431| sleep CACNA1I;SLC29A1;HTR2A GO:0045821| positive regulation of glycolysis HTR2A GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0008285| negative regulation of cell proliferation ADRA1A;CYP1B1;PPARG;PTGS2;OPRM1 GO:0046883| regulation of hormone secretion HTR1A;HTR2A GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A;HTR7 GO:0043267| negative regulation of potassium ion transport HTR2A GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0007165| signal transduction ADRA2A;ADRA1A;CACNA1I;PLA2G1B;HTR7;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HRH2;HTR2A;CNR1;GPR12;CNR2;OPRM1;HRH1;OPRD1 GO:0007610| behavior HTR1A;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;HRH2;PTGS2;HRH1;ADRA1A GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0006939| smooth muscle contraction HTR7;ADRA1A;HTR2A GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;ADRA1A;TRPV4;HTR2A;OPRM1 GO:0050796| regulation of insulin secretion ADRA2A;CNR1 GO:0007613| memory HTR2A;CNR1;HRH2;PTGS2;HRH1;CHRNA7 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0046718| entry of virus into host cell HTR2A 19655:[DB14011 DB01537] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01537|4-Bromo-2,5-dimethoxyphenethylamine HTR2C;HTR2A common genes HTR2A common pathways GO:0050795| regulation of behavior HTR2A;HTR1A GO:0007626| locomotory behavior HTR2C;OPRM1;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;HTR2C GO:0014824| artery smooth muscle contraction HTR2A GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2C;HTR2A GO:0044380| protein localization to cytoskeleton HTR2A GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;HTR2C;ABCG2 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;HTR2C;CHRNA7;GPR12;HTR2A GO:0007210| serotonin receptor signaling pathway HTR2C;HTR1A;HTR2A GO:0007568| aging CYP1A1;CAT;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;HTR2C;TRPA1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2C;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0043406| positive regulation of MAP kinase activity HTR2A GO:0014059| regulation of dopamine secretion HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;HTR2C GO:0007202| activation of phospholipase C activity HTR2A;GPR55 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;HTR2C;ALOX15 GO:0008219| cell death HTR2A GO:0001659| temperature homeostasis HTR2A;GPX1;TRPV1 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A;HTR2C GO:0048148| behavioral response to cocaine HTR2A GO:0045821| positive regulation of glycolysis HTR2A GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPV1;TRPA1 GO:0033674| positive regulation of kinase activity HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0016032| viral reproduction HTR2A;VDAC1 GO:0007268| synaptic transmission HTR2C;GLRB;VDAC1;GLRA1;CACNA1G;HTR2A;GLRA3;OPRD1;OPRM1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;TRPA1 GO:0007610| behavior HTR2C;HTR1A;HTR2A GO:0007165| signal transduction PPARG;GPR18;SMPD1;HTR2C;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A GO:0006939| smooth muscle contraction HTR2A GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:0046718| entry of virus into host cell HTR2A GO:0001662| behavioral fear response HTR1A;HTR2C;VDAC1 GO:0046883| regulation of hormone secretion HTR1A;HTR2A GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;HTR2C GO:0043267| negative regulation of potassium ion transport HTR2A 19656:[DB14011 DB03666] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03666|3'-Azido-3'-Deoxythymidine-5'-Monophosphate DTYMK;tmk common genes common pathways GO:0045445| myoblast differentiation HMGCR;DTYMK GO:0043627| response to estrogen stimulus PPARG;DTYMK GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;DTYMK GO:0015949| nucleobase-containing small molecule interconversion DTYMK;GSR GO:0071363| cellular response to growth factor stimulus DTYMK;TRPV1;OPRD1;CAT GO:0046686| response to cadmium ion DTYMK;CAT 19657:[DB14011 DB08972] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08972|Flumequine CYP1A2 common genes CYP1A2 common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0008202| steroid metabolic process CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;CYP1A1;IDO1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 19658:[DB14011 DB00765] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00765|Metyrosine TH common genes common pathways GO:0007605| sensory perception of sound TH;SOD1;GPX1 GO:0032355| response to estradiol stimulus TH;PTGS2;CYP1A2;CAT GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TH;TRPV1 GO:0009416| response to light stimulus AANAT;TH GO:0001666| response to hypoxia TH;CAT;CHRNA7;CYP1A1 GO:0035902| response to immobilization stress CYP1A2;TH;PPARG;CYP1A1 GO:0070848| response to growth factor stimulus OPRM1;TH GO:0007626| locomotory behavior SOD1;TH;OPRM1 GO:0071333| cellular response to glucose stimulus TH;SLC29A1 GO:0007612| learning PTGS2;TH;VDAC1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;TH;PTGS2;CNR2;OPRM1;CYP1A2 GO:0035094| response to nicotine CHRNA7;TH;CNR1 GO:0035900| response to isolation stress NAPEPLD;TH GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;TH;CYP3A4 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2;TH GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;TH;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0051412| response to corticosterone stimulus AANAT;TH GO:0007601| visual perception TH;CRYZ;GLRA1;CYP1B1;GLRB GO:0007613| memory PTGS2;HTR2A;TH;CNR1;CHRNA7 GO:0033076| isoquinoline alkaloid metabolic process TH;CYP2D6 GO:0001975| response to amphetamine TH;SOD1;CNR2 GO:0043434| response to peptide hormone stimulus TH;TRPV1 GO:0050890| cognition CHRNA7;TH GO:0014823| response to activity TH;CAT GO:0010043| response to zinc ion TH;AANAT GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;TH;CYP1A2;PTGS2;ACAT1;AANAT GO:0042755| eating behavior TH;OPRD1;OPRM1 GO:0007507| heart development PPARG;TH GO:0042136| neurotransmitter biosynthetic process DAGLA;TH GO:0071312| cellular response to alkaloid TRPV1;TH GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;TH;CAT GO:0008016| regulation of heart contraction CACNA1H;TH GO:0009635| response to herbicide CYP1A1;TH GO:0031667| response to nutrient levels SOD1;TH 19659:[DB14011 DB05824] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05824|CNS-5161 GRIN1 common genes common pathways GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;GRIN1;CACNA1H;GLRA3;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0008344| adult locomotory behavior GRIN1;OPRD1 GO:0006812| cation transport GRIN1;TRPM8 GO:0001975| response to amphetamine SOD1;GRIN1;CNR2 GO:0007613| memory CHRNA7;GRIN1;PTGS2;CNR1;HTR2A GO:0043576| regulation of respiratory gaseous exchange GRIN1;GLRA1 GO:0065009| regulation of molecular function GRIN1;TRPV1 GO:0043524| negative regulation of neuron apoptosis GRIN1;SOD1 GO:0006816| calcium ion transport TRPV2;CHRNA7;CACNA1H;GRIN1;TRPV3;TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;TRPA1 GO:0001964| startle response GRIN1;GLRA1;GLRB GO:0008542| visual learning GRIN1;HMGCR GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR1;HTR2A;OPRM1;GRIN1;PTGS2;CNR2;OPRD1 GO:0045471| response to ethanol OPRM1;GRIN1;HMGCR;SOD1;CNR1;CAT GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;GRIN1;PTGS2;CNR1;SOD1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential GRIN1;CHRNA7 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;GRIN1;GPR12;HTR2A;CHRNA7 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;CACNA1H;GRIN1 GO:0050905| neuromuscular process GLRB;GLRA1;GRIN1 GO:0043278| response to morphine CNR1;GRIN1;OPRM1 GO:0043523| regulation of neuron apoptosis GRIN1;GPX1 GO:0007611| learning or memory CHRNA7;CNR1;GRIN1 GO:0007612| learning PTGS2;GRIN1;VDAC1 GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B;GRIN1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;GRIN1;OPRM1;CHRNA7;SLC29A1;GLRA1;GLRB;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PPARG;PLA2G1B 19660:[DB14011 DB01109] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0051450| myoblast proliferation HGF;GPX1 GO:0008283| cell proliferation FGF1;HTR1A;GPX1;CYP1A1;HGF GO:0043537| negative regulation of blood vessel endothelial cell migration FGF2;PPARG GO:0007584| response to nutrient SERPINC1;CNR1;HMGCR;PPARG GO:1902042| HGF;GPX1 GO:0061844| PF4;PLA2G1B GO:0051781| positive regulation of cell division FGF4;FGF1;FGF2;FGFR2;CAT GO:0009791| post-embryonic development CYP1A2;FGFR2 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;FGFR4;HMGCR;CNR1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;HGF GO:0040014| regulation of multicellular organism growth SOD1;FGFR2 GO:0043950| positive regulation of cAMP-mediated signaling PF4;OPRM1 GO:0065009| regulation of molecular function FGF19;TRPV1;FGF4 GO:0007165| signal transduction CNR1;GPR12;HTR2A;FGF1;HTR1A;GPR55;OPRD1;FGF2;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;FGF4;CACNA1I;PLA2G1B GO:0007420| brain development FGFR1;ACAT1 GO:0060055| angiogenesis involved in wound healing HPSE;GPX1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;HGF GO:0001934| positive regulation of protein phosphorylation FGF4;FGF1;CHRNA7;FGF19 GO:0010629| negative regulation of gene expression OPRD1;FGFR1;FGF19 GO:0048565| digestive tract development FGFR2;CYP1A1 GO:0007595| lactation SLC29A1;SERPINC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HGF;HTR2A GO:0006955| immune response PF4;CNR2;OPRD1 GO:0010976| positive regulation of neuron projection development FGFR1;CNR1 GO:0006954| inflammatory response ALOX5;PTGS1;SELP;PTGS2;CNR2;ALOX15;IDO1;TRPV1;PF4 GO:0001889| liver development ACAT1;HGF;CYP1A1 GO:0006351| transcription, DNA-dependent PPARG;FGFR1 GO:0001525| angiogenesis FGFR2;PTGS2;FGF2;FGFR1;FGF1;CYP1B1 GO:0048469| cell maturation PPARG;FGFR1 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;FGFR2;CAT GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;HPSE;CYP1B1 GO:0061045| negative regulation of wound healing FGF2;HMGCR GO:0045165| cell fate commitment FGFR2;PPARG GO:0007399| nervous system development GLRB;SMPD1;FGF19;FGF2 GO:0006915| apoptotic process FGFR2;GPX1;VDAC1 GO:0000187| activation of MAPK activity FGF2;SOD1;FGF1;CHRNA7;PLA2G1B;HGF GO:0030855| epithelial cell differentiation FGFR2;VDAC1;PPARG GO:0045766| positive regulation of angiogenesis FGF1;FGF2;CHRNA7;HGF;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade FGFR4;ALOX15;FGF4;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;FGF2;CHRNA7;FGFR2;FGF19 GO:0043406| positive regulation of MAP kinase activity FGF2;FGF1;FGFR1;HTR2A GO:0010628| positive regulation of gene expression PF4;FGF4;TRPV4;FGFR4 GO:0001657| ureteric bud development FGFR1;CAT;FGFR2 GO:0030282| bone mineralization FGFR2;PTGS2;ALOX15 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FGFR1;CAT;SELP;HGF GO:0048514| blood vessel morphogenesis FGFR1;CYP1B1 GO:0010468| regulation of gene expression FGF4;CYP1A2;FGFR1 GO:0030595| leukocyte chemotaxis PF4;CNR2 GO:0034605| cellular response to heat FGF1;PTGS2;TRPV1;TRPV4 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;FGF2;TRPA1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway PF4;GPR18;PPARG;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0007605| sensory perception of sound FGFR1;SOD1;GPX1 GO:0043085| positive regulation of catalytic activity FGFR4;SOD1 GO:0042593| glucose homeostasis PPARG;TRPV4;FGFR4;CNR1 GO:0031100| organ regeneration HGF;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;FGF2 GO:0006355| regulation of transcription, DNA-dependent PPARG;FGFR1 GO:0016525| negative regulation of angiogenesis PF4;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade FGFR2;FGF19;GPX1;FGF1;FGFR1;FGF2;HGF;FGFR4;FGF4;F10;HPSE GO:0060326| cell chemotaxis ABCC1;HGF GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;FGFR2 GO:0050728| negative regulation of inflammatory response HGF;CNR2 GO:0046330| positive regulation of JNK cascade TRPV4;FGF19 GO:0030324| lung development FGF1;FGFR1;CYP1A2;FGFR2 GO:0042127| regulation of cell proliferation PTGS2;FGFR1;PTGS1;PF4 GO:0042060| wound healing FGF2;OPRM1;FGFR2;HPSE;ALOX15 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;SELP;FGFR2;PF4;CYP1A1;IDO1 GO:0043312| neutrophil degranulation HPSE;CAT;ALOX5 GO:0007155| cell adhesion HPSE;CYP1B1;SELP GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;FGFR2;PPARG;TRPV1;TRPV4 GO:0071300| cellular response to retinoic acid FGFR2;PPARG GO:0043066| negative regulation of apoptotic process HGF;FGF4;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0002576| platelet degranulation SELP;SOD1;HGF;PF4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;FGF2;FGF1;FGF4;PLA2G1B;HGF;PF4;PPARG GO:0008284| positive regulation of cell proliferation FGFR4;HGF;FGF4;CHRNA7;FGFR2;FGF19;HTR2A;FGF1;FGFR1;HTR1A;HMGCR;FGF2;PTGS2 19661:[DB14011 DB03988] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways GO:0042594| response to starvation PPARG;ADCYAP1;ACAT1 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;GLRA3;OPRM1;OPRD1;ADCYAP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADCYAP1;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;ADCYAP1;HMGCR;PTGS2;HTR2A;HTR1A GO:0045786| negative regulation of cell cycle PTGS2;ADCYAP1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;ADCYAP1;HMGCR;OPRM1;HTR2A;GPR55 GO:0001541| ovarian follicle development SOD1;ADCYAP1 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADCYAP1;PTGS2 GO:0010628| positive regulation of gene expression ADCYAP1;TRPV4 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;GPR12;CNR1;GPR55;HTR1A;ADCYAP1;OPRD1;CNR2;OPRM1 GO:0007565| female pregnancy ADCYAP1;IDO1 GO:0010976| positive regulation of neuron projection development ADCYAP1;CNR1 GO:0045471| response to ethanol CAT;SOD1;CNR1;OPRM1;ADCYAP1;HMGCR GO:0019233| sensory perception of pain CNR1;HTR2A;ADCYAP1;OPRD1;PTGS2;CNR2;OPRM1;TRPV1;TRPA1 GO:0007399| nervous system development ADCYAP1;SMPD1;GLRB GO:0060078| regulation of postsynaptic membrane potential ADCYAP1;CHRNA7 GO:0043267| negative regulation of potassium ion transport HTR2A;ADCYAP1 GO:0001662| behavioral fear response VDAC1;ADCYAP1;HTR1A GO:0071651| positive regulation of chemokine (C-C motif) ligand 5 production TRPV4;ADCYAP1 GO:0007204| elevation of cytosolic calcium ion concentration ADCYAP1;OPRM1;HTR2A;TRPV1;TRPV4 19662:[DB14011 DB11793] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways GO:0006915| apoptotic process GPX1;PARP1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;PARP1 GO:0034599| cellular response to oxidative stress GPX1;CAT;PARP1;SOD1;GSR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;PARP1 GO:0043312| neutrophil degranulation ALOX5;GUSB;CAT GO:0032869| cellular response to insulin stimulus PARP1;PPARG;PLA2G1B GO:0010332| response to gamma radiation PARP1;GPX1 GO:0071294| cellular response to zinc ion GLRA1;PARP1 GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0008152| metabolic process ACAT1;GUSB;SMPD1 19663:[DB14011 DB03316] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways GO:0007565| female pregnancy TGFB3;EPN1;IDO1 GO:0043524| negative regulation of neuron apoptosis TGFB3;SOD1 GO:1904706| PPARG;TGFB3 GO:0048565| digestive tract development TGFB3;CYP1A1 GO:0006955| immune response OPRD1;CNR2;TNFSF13B GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;TGFB3;SOD1;CNR1 GO:0008283| cell proliferation GPX1;HTR1A;TNFSF13B;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;TGFB3 GO:0043627| response to estrogen stimulus TGFB3;PPARG GO:0045740| positive regulation of DNA replication PLA2G1B;TGFB3 GO:0051781| positive regulation of cell division CAT;TGFB3 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;PLA2G1B;TNFSF13B;CACNA1I;SMPD1;PPARG;GPR18 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TGFB3 GO:0042060| wound healing ALOX15;TGFB3;OPRM1 GO:0002576| platelet degranulation TGFB3;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;TNFSF13B GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TGFB3 GO:0050714| positive regulation of protein secretion TGFB3;PLA2G1B GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1;TGFB3 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;TGFB3 GO:0007568| aging CYP1A1;NAPEPLD;HTR2A;SOD1;CNR1;TGFB3;PTGS2;HMGCR;CAT GO:0002376| immune system process TNFSF13B;IDO1 19664:[DB14011 DB06185] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06185|Forodesine PNP common genes common pathways GO:0006955| immune response CNR2;OPRD1;PNP GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0043312| neutrophil degranulation PNP;ALOX5;CAT GO:0042493| response to drug ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;PNP;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 19665:[DB14011 DB08445] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 19666:[DB14011 DB03319] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03319|(S)-ATPA GRIA2 common genes common pathways GO:0007268| synaptic transmission CACNA1G;GLRA1;GLRB;VDAC1;OPRD1;OPRM1;HTR2A;GLRA3;GRIA2 GO:0007165| signal transduction GRIA2;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;GRIA2;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GRIA2;GLRA1;TRPV1;GLRB GO:0034220| ion transmembrane transport GLRB;TRPV1;GLRA1;TRPA1;CHRNA7;GRIA2;GLRA3 19667:[DB14011 DB05875] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes PTGS2 common pathways GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT;CYP1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0042493| response to drug ABCC1;SMPD1;BCHE;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;CYP19A1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP19A1;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0006694| steroid biosynthetic process CYP19A1;CYP17A1;HMGCR GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG;BCHE GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PTGS2;CNR2;ALOX5;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0019233| sensory perception of pain OPRD1;PTGS2;CNR2;OPRM1;CNR1;HTR2A;TRPV1;TRPA1 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0050727| regulation of inflammatory response PTGS2 GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP19A1 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;CYP2C9;PPARG 19668:[DB14011 DB00958] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00958|Carboplatin XDH;MPO;GSTT1;MT1A;MT2A;SOD1;GSTP1;GSTM1;NQO1;SLC31A1;SLC31A2;ATP7A;ATP7B;ABCG2;ABCC2 common genes ABCG2;SOD1 common pathways GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0006855| drug transmembrane transport ABCG2;ABCC2;SLC31A1;ABCC1 GO:0006809| nitric oxide biosynthetic process NQO1;CYP1B1 GO:0001895| retina homeostasis SOD1 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;ATP7A;SLC31A2;TRPM8;ATP7B;CACNA1G;SLC31A1;TRPA1;GLRA1 GO:0009636| response to toxin GSTP1;CYP1B1;CYP1A1;NQO1;CAT;GPX1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;NQO1;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0006919| activation of caspase activity XDH;PPARG GO:0046620| regulation of organ growth SOD1 GO:0070301| cellular response to hydrogen peroxide NQO1;CYP1B1 GO:0007584| response to nutrient HMGCR;CNR1;NQO1;PPARG GO:0006812| cation transport ATP7A;TRPM8;ATP7B GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0006749| glutathione metabolic process GPX1;SOD1;GSTT1;GSR;GSTP1;GSTM1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;MT1A;ATP7A GO:0042178| xenobiotic catabolic process GSTM1;CRYZ GO:0001890| placenta development SOD1;PPARG GO:0010043| response to zinc ion ATP7A;AANAT GO:0032869| cellular response to insulin stimulus PLA2G1B;GSTP1;PPARG GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0002262| myeloid cell homeostasis SOD1 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0040014| regulation of multicellular organism growth SOD1 GO:0060047| heart contraction GPX1;SOD1 GO:0001819| positive regulation of cytokine production SOD1 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0007565| female pregnancy ABCC2;IDO1 GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0046415| urate metabolic process ABCG2 GO:0043524| negative regulation of neuron apoptosis SOD1 GO:0010629| negative regulation of gene expression OPRD1;XDH GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:0007595| lactation SLC29A1;XDH;ATP7A;ATP7B GO:0019430| removal of superoxide radicals MPO;SOD1;ATP7A;NQO1 GO:1904706| PPARG;GSTP1 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;ABCC2 GO:0043087| regulation of GTPase activity SOD1 GO:0019226| transmission of nerve impulse SOD1 GO:0045471| response to ethanol GSTP1;NQO1;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0048678| response to axon injury SOD1 GO:0001889| liver development ACAT1;CYP1A1;ATP7A GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0000303| response to superoxide SOD1 GO:0071294| cellular response to zinc ion MT1A;MT2A;GLRA1 GO:0008090| retrograde axon cargo transport SOD1 GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;CAT;SOD1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0042428| serotonin metabolic process ATP7A;HTR1A GO:0008152| metabolic process ACAT1;SMPD1;GSTM1;GSTP1 GO:0006805| xenobiotic metabolic process CYP1B1;GSTP1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;NQO1;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;ABCC2;TRPM8 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0001541| ovarian follicle development SOD1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0043200| response to amino acid stimulus GLRA3;GLRB;GSTP1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;ATP7B;GLRA1;TRPA1;TRPV1;GLRB;ATP7A GO:0046716| muscle cell homeostasis SOD1 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0007283| spermatogenesis CNR1;SOD1 GO:0046688| response to copper ion ATP7A;ATP7B;AANAT;SOD1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0010468| regulation of gene expression CYP1A2;ATP7A GO:0071456| cellular response to hypoxia ATP7A;SLC29A1;OPRD1;PTGS2 GO:0006810| transport TRPV2;ABCC1;TRPV1;CACNA1I;ABCG2;ABCC2 GO:0007568| aging NQO1;CYP1A1;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;MPO;CAT GO:0042554| superoxide anion generation SOD1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;NQO1;GSTP1 GO:0043085| positive regulation of catalytic activity ATP7A;SOD1 GO:0007605| sensory perception of sound SOD1;GPX1 GO:0071280| cellular response to copper ion CYP1A1;ATP7A;CYP1A2 GO:0048538| thymus development SOD1 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0010041| response to iron(III) ion CYP1A1;ATP7A GO:0098869| CAT;GPX1;PTGS1;PTGS2;GSTT1;GSR;GSTP1 GO:0006979| response to oxidative stress ABCC2;NQO1;GPX1;MPO;PTGS1;CAT;PTGS2;SOD1 GO:0007569| cell aging SOD1 GO:0055114| oxidation-reduction process CAT;MPO;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;XDH;PTGS2;CYP3A7;CYP1A2;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;NQO1 GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0042493| response to drug ABCC2;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0099133| ABCC1;ABCC2 GO:0022900| electron transport chain GSR;IDO1;CYP1A2;XDH GO:0032094| response to food MPO;OPRM1;CYP1A1 GO:0015886| heme transport ABCG2 GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0034465| response to carbon monoxide SOD1 GO:0006801| superoxide metabolic process NQO1;SOD1 GO:0010042| response to manganese ion ATP7A;PTGS2 GO:0097332| SOD1 GO:0034599| cellular response to oxidative stress GSTP1;GSR;GPX1;CAT;SOD1 GO:0033344| cholesterol efflux ABCG2 GO:0071230| cellular response to amino acid stimulus ATP7A;GLRA1 GO:0030199| collagen fibril organization CYP1B1;ATP7A GO:0071284| cellular response to lead ion PTGS2;ATP7A GO:0032496| response to lipopolysaccharide CYP1A1;ABCC2;IDO1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1;MPO GO:0000302| response to reactive oxygen species GSTP1;SOD1;GPX1;CAT GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0043312| neutrophil degranulation GSTP1;CAT;ALOX5;MPO GO:0010288| response to lead ion ATP7A;CAT GO:0007626| locomotory behavior ATP7A;SOD1;OPRM1 GO:0002576| platelet degranulation SOD1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;MPO;GPX1;CAT;NQO1;GSTP1 GO:0009612| response to mechanical stimulus MPO;TRPV4;PPARG GO:0035722| interleukin-12-mediated signaling pathway SOD1 GO:1902177| SOD1 19669:[DB14011 DB08280] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08280|(1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE HSD11B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;HSD11B1;PTGS1;ALOX5;GPX1 GO:0030324| lung development HSD11B1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;HSD11B1;CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1 GO:0006704| glucocorticoid biosynthetic process HSD11B1;CYP17A1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;HSD11B1;NAAA;PTGS1;GPX1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 19670:[DB14011 DB06989] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06989|{4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways GO:0043312| neutrophil degranulation PTPRB;CAT;ALOX5 GO:0001525| angiogenesis PTGS2;CYP1B1;PTPRB 19671:[DB14011 DB04880] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04880|Enoximone PDE3A common genes common pathways GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;PDE3A;GPR18;PPARG GO:0043117| positive regulation of vascular permeability TRPV4;PDE3A GO:0006629| lipid metabolic process PDE3A;PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1 GO:0051591| response to cAMP AANAT;PDE3A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;PDE3A;GPR18;PPARG GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;PDE3A GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;PDE3A 19672:[DB14011 DB12007] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12007|Isoflavone PPARA;PPARG common genes PPARG common pathways GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PPARA GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0042594| response to starvation ACAT1;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PPARA GO:0030308| negative regulation of cell growth PPARG GO:0042060| wound healing ALOX15;PPARA;OPRM1 GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0050728| negative regulation of inflammatory response CNR2;PPARA GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA GO:0006631| fatty acid metabolic process PTGS1;PPARA;PTGS2;ALOX15 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0030224| monocyte differentiation PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PPARG;GPR18 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0001666| response to hypoxia CYP1A1;PPARA;CAT;CHRNA7 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;PPARA;PTGS2;CYP1A2;HMGCR;NAAA;PTGS1;GPX1;PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0048469| cell maturation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0019216| regulation of lipid metabolic process CNR1;PPARA;HMGCR;PPARG;CYP1A1 GO:1905461| PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0006919| activation of caspase activity PPARG GO:0032868| response to insulin stimulus TRPV4;CAT;AANAT;PPARA 19673:[DB14011 DB00382] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00382|Tacrine ACHE;BCHE;CES1;CYP1A2;ABCB1 common genes CYP1A2 common pathways GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;CYP1A1;IDO1 GO:0007612| learning PTGS2;VDAC1;BCHE GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0007155| cell adhesion ACHE;CYP1B1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0055114| oxidation-reduction process CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1;ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0007517| muscle organ development ACHE;CACNA1H GO:0042493| response to drug ABCB1;ABCG2;ABCC1;SMPD1;BCHE;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0006810| transport ABCC1;ABCB1;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0010468| regulation of gene expression CYP1A2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0009611| response to wounding CYP1A1;ACHE;GPX1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0030855| epithelial cell differentiation CES1;PPARG;VDAC1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;ABCB1;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0008152| metabolic process SMPD1;ACAT1;CES1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;CES1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0008283| cell proliferation GPX1;ACHE;HTR1A;CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0008285| negative regulation of cell proliferation CYP1B1;BCHE;PPARG;PTGS2;OPRM1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 19674:[DB14011 DB06932] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1 GO:0045766| positive regulation of angiogenesis PDPK1;CYP1B1;CHRNA7 GO:0043524| negative regulation of neuron apoptosis PDPK1;SOD1 GO:0035556| intracellular signal transduction PLA2G1B;PDPK1 GO:0006351| transcription, DNA-dependent PPARG;PDPK1 GO:0032869| cellular response to insulin stimulus PPARG;PDPK1;PLA2G1B 19675:[DB14011 DB07724] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07724|Indeglitazar NCOA1;PPARA;PPARD;PPARG common genes PPARG common pathways GO:0030224| monocyte differentiation PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;NCOA1;PPARD;PPARG GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0045893| positive regulation of transcription, DNA-dependent NCOA1;PPARA;PPARD;PPARG GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PPARA;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA;PPARD GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A PPARD;CAT;CYP1A1;PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2;PPARD GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0032526| response to retinoic acid PPARG GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0042127| regulation of cell proliferation PTGS1;PPARD;PTGS2 GO:0042060| wound healing PPARD;OPRM1;PPARA;ALOX15 GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PPARD;PPARA GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0042594| response to starvation PPARG;ACAT1 GO:0008284| positive regulation of cell proliferation CHRNA7;PPARD;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA1;PPARA;PLA2G1B;PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;PPARD;HMGCR;SOD1;GPX1;CAT GO:0071300| cellular response to retinoic acid PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0006915| apoptotic process PPARD;GPX1;VDAC1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG GO:0015758| glucose transport PLA2G1B;PPARD GO:0031000| response to caffeine PPARG GO:0010033| response to organic substance PPARD;CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0010628| positive regulation of gene expression TRPV4;PPARD GO:0001666| response to hypoxia PPARA;CHRNA7;CAT;CYP1A1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0071456| cellular response to hypoxia PTGS2;PPARD;OPRD1;SLC29A1 GO:0046697| decidualization PTGS2;PPARD GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0015909| long-chain fatty acid transport PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0006351| transcription, DNA-dependent NCOA1;PPARA;PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARD;PPARA GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;PPARD GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARA;PPARD;PPARG GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP1A2;PTGS2;PPARD;HMGCR;CYP3A4;NAPEPLD;PPARA GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;NCOA1;SOD1;CNR1;PTGS2 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0032868| response to insulin stimulus CAT;AANAT;PPARA;TRPV4 GO:0008283| cell proliferation GPX1;PPARD;HTR1A;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0006919| activation of caspase activity PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0014823| response to activity PPARD;CAT GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARD;PPARG GO:0019395| fatty acid oxidation PPARG;PPARD GO:0060612| adipose tissue development ACAT1;PPARD GO:0001890| placenta development PPARD;SOD1;PPARG GO:0055088| lipid homeostasis PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:1905461| PPARG GO:0007566| embryo implantation PPARD;PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;PPARA;NCOA1;CNR1 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD 19676:[DB14011 DB01762] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway SLC5A8;PTGS2 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;SLC5A8;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8 GO:0008152| metabolic process SMPD1;FAH;ACAT1 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;SLC16A1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0042593| glucose homeostasis TRPV4;PPARG;SLC16A1;CNR1 GO:0055085| transmembrane transport SLC16A7;CACNA1H;TRPV3;TRPV2;SLC16A1;CACNA1G;ABCC1;TRPA1;SLC16A3;SLC5A8;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8 GO:0006915| apoptotic process GPX1;SLC5A8;VDAC1 GO:0032094| response to food CYP1A1;SLC16A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;SLC16A1 19677:[DB14011 DB02089] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02089|CP-526423 PYGL common genes common pathways GO:0008152| metabolic process SMPD1;PYGL;ACAT1 GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;PYGL GO:0043312| neutrophil degranulation CAT;ALOX5;PYGL 19678:[DB14011 DB00527] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0002027| regulation of heart rate SCN5A;CALM1;SCN10A;CACNA1G GO:0086091| SCN5A;CACNA1G GO:0071277| cellular response to calcium ion ALOX15;SCN5A GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SCN10A;SCN5A;CACNA1H GO:0019228| regulation of action potential in neuron SCN10A;CACNA1G;CACNA1I;CACNA1H;SCN5A GO:0051592| response to calcium ion AANAT;CALM1 GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;SCN10A;TRPA1;TRPV1 GO:0007600| sensory perception SCN10A;OPRM1;TRPV2 GO:0086010| SCN5A;CACNA1H;CACNA1I;SCN10A;CACNA1G GO:0034765| regulation of ion transmembrane transport SCN10A;CACNA1G;CACNA1I;CACNA1H;SCN5A GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN5A;SCN10A;CACNA1G GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0086046| CACNA1G;SCN5A GO:0008285| negative regulation of cell proliferation PPARG;BCHE;CYP1B1;OPRM1;PTGS2 GO:0006811| ion transport TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPA1;GLRA1;CACNA1G;SCN10A;CHRNA7;SCN5A;TRPV2;GLRA3;TRPV3;CACNA1H GO:0086045| CACNA1G;SCN5A GO:0002576| platelet degranulation CALM1;SOD1 GO:0086015| CACNA1G;SCN5A GO:0035307| positive regulation of protein dephosphorylation SMPD1;CALM1 GO:0007612| learning PTGS2;VDAC1;BCHE GO:0086016| SCN5A;SCN10A;CACNA1G GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;PPARG;CYP1A1;TRPA1;BCHE;SMPD1;ABCC1;ABCG2 GO:0006936| muscle contraction GLRA1;CACNA1H;CALM1 GO:0007186| G-protein coupled receptor signaling pathway CALM1;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PPARG;GPR18 GO:0055085| transmembrane transport TRPV3;CACNA1H;SCN5A;CALM1;TRPV2;TRPA1;ABCC1;SCN10A;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4 GO:0086002| CACNA1G;SCN5A 19679:[DB14011 DB00253] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;PLA2G1B GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;NR3C1;CHRNA7 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 19680:[DB14011 DB05386] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0042493| response to drug ABCG2;BCHE;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0065009| regulation of molecular function TRPV1;CSF2RA GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;BCHE GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG 19681:[DB14011 DB03430] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03430|(2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile LCTL common genes common pathways 19682:[DB14011 DB07294] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07294|3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid RARG common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0043066| negative regulation of apoptotic process CAT;RARG;GPX1;SOD1;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;RARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;RARG GO:0032526| response to retinoic acid PPARG;RARG GO:0010628| positive regulation of gene expression RARG;TRPV4 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0006351| transcription, DNA-dependent PPARG;RARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;RARG;PPARG;CYP1B1 GO:0043010| camera-type eye development CYP1A1;RARG 19683:[DB14011 DB05429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05429|CAT-213 CCL11 common genes common pathways GO:0061844| PLA2G1B;CCL11 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;CCL11 GO:0006955| immune response OPRD1;CNR2;CCL11 GO:0006954| inflammatory response ALOX5;PTGS1;CCL11;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0009314| response to radiation CCL11;CAT;OPRM1;PTGS2 GO:0045766| positive regulation of angiogenesis CCL11;CHRNA7;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CCL11;CHRNA7;TRPV4;ALOX15 GO:0071356| cellular response to tumor necrosis factor TRPV1;CCL11 GO:0007186| G-protein coupled receptor signaling pathway CCL11;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;GPR18;PPARG GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;CCL11;CHRNA7;HTR2A;GPR12 GO:0030593| neutrophil chemotaxis PLA2G1B;CCL11 GO:0007015| actin filament organization PLA2G1B;TRPV4;CCL11 GO:0030838| positive regulation of actin filament polymerization ALOX15;CCL11 GO:0009615| response to virus CCL11;CYP1A1 GO:0007155| cell adhesion CCL11;CYP1B1 19684:[DB14011 DB07689] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07689|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;DHRS4L1;CYP1A2;CAT;ALOX5;GPX1;PTGS1;CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 19685:[DB14011 DB06127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06127|Bisegliptin DPP4 common genes common pathways GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;DPP4 GO:0001666| response to hypoxia DPP4;CYP1A1;CHRNA7;CAT GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 19686:[DB14011 DB07574] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07574|2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE STMN4;TUBB2B;TUBA1A;TUBA1C;TUBA1B common genes common pathways GO:0007399| nervous system development GLRB;SMPD1;TUBB2B 19687:[DB14011 DB09051] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09051|Elosulfase alfa GALNS common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;GALNS GO:0008152| metabolic process SMPD1;ACAT1;GALNS 19688:[DB14011 DB06781] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06781|Difluprednate NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;NR3C1;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0002933| CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0036378| CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;TRPV1;TRPV4 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 19689:[DB14011 DB00939] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes PTGS2;PTGS1;ALOX5 common pathways GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0009750| response to fructose stimulus PTGS2 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0043312| neutrophil degranulation ALOX5;CAT GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0071284| cellular response to lead ion PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:2001300| ALOX5 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;SLC22A6;CACNA1G;SLCO1C1;ABCC1;KCNQ2;TRPV2;KCNQ3;CACNA1H;TRPV3 GO:0051260| protein homooligomerization SLC22A6;GLRA1;GLRA3;ACAT1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:1902219| PTGS2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0007568| aging CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CYP1A1 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS2;CNR2;ALOX5;PTGS1 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;KCNQ2;OPRD1;OPRM1;KCNQ3;HTR2A;GLRA3 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:1990776| PTGS2 GO:0007399| nervous system development KCNQ2;SMPD1;GLRB GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0098656| SLC22A6;VDAC1 GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0006811| ion transport GLRA1;TRPA1;SLCO1C1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;KCNQ3;GLRA3;TRPV3;CACNA1H;CHRNA7;KCNQ2;TRPV2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;KCNQ3;CACNA1H;KCNQ2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 19690:[DB14011 DB02800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways GO:0051262| protein tetramerization CAT;SHMT1;HMGCR GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPV1;TRPM8;SHMT1;CAT 19691:[DB14011 DB04931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04931|Afamelanotide MC1R common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MC1R;PPARG;PLA2G1B GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MC1R GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;MC1R GO:0007186| G-protein coupled receptor signaling pathway PPARG;MC1R;GPR18;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger MC1R;CNR1;OPRD1;CNR2;OPRM1 GO:0035556| intracellular signal transduction MC1R;PLA2G1B GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;MC1R;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0009650| UV protection GPX1;CAT;MC1R 19692:[DB14011 DB09151] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09151|Flutemetamol (18F) APP common genes common pathways GO:0032930| positive regulation of superoxide anion generation SOD1;APP GO:0061844| PLA2G1B;APP GO:0008285| negative regulation of cell proliferation APP;PPARG;CYP1B1;PTGS2;OPRM1 GO:0008344| adult locomotory behavior OPRD1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP GO:1900273| APP;CHRNA7 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7;APP GO:0007204| elevation of cytosolic calcium ion concentration APP;TRPV1;TRPV4;OPRM1;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;APP GO:0040014| regulation of multicellular organism growth APP;SOD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0008542| visual learning APP;HMGCR GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;PLA2G1B;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;PPARG GO:1902004| CHRNA7;APP GO:0001934| positive regulation of protein phosphorylation APP;CHRNA7 GO:0007268| synaptic transmission GLRA1;CACNA1G;APP;GLRB;VDAC1;GLRA3;HTR2A;OPRM1;OPRD1 GO:0010629| negative regulation of gene expression APP;OPRD1 GO:0071320| cellular response to cAMP AANAT;APP GO:1990090| APP;TRPV1 GO:0007399| nervous system development SMPD1;APP;GLRB GO:0043065| positive regulation of apoptotic process SMPD1;APP;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0001774| microglial cell activation APP;TRPV1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential APP;CHRNA7 GO:0051262| protein tetramerization APP;HMGCR;CAT GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;APP GO:0006915| apoptotic process APP;VDAC1;GPX1 GO:0051260| protein homooligomerization GLRA1;APP;GLRA3;ACAT1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;APP;TRPV1 GO:0006979| response to oxidative stress APP;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0010468| regulation of gene expression APP;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;APP;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0098815| APP;CHRNA7 GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0019731| antibacterial humoral response PLA2G1B;APP GO:0050808| synapse organization CHRNA7;APP GO:0050830| defense response to Gram-positive bacterium APP;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;APP;TRPV4;TRPV1 GO:0007155| cell adhesion CYP1B1;APP GO:0045087| innate immune response PPARG;APP GO:0010288| response to lead ion CAT;APP GO:0002576| platelet degranulation APP;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;PPARG;PLA2G1B GO:0007626| locomotory behavior APP;SOD1;OPRM1 GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:1905906| APP;CHRNA7 GO:0007612| learning APP;VDAC1;PTGS2 GO:0008203| cholesterol metabolic process APP;HMGCR;CAT GO:0007611| learning or memory CHRNA7;CNR1;APP 19693:[DB14011 DB05945] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;ANTXR1;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0031532| actin cytoskeleton reorganization TRPV4;ANTXR1 19694:[DB14011 DB07815] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways GO:0008152| metabolic process AADACL2;ACAT1;SMPD1 19695:[DB14011 DB11131] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11131|Capsicum oleoresin TRPV1 common genes TRPV1 common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1 GO:0071468| cellular response to acidity TRPV1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;TRPA1 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;TRPV2 GO:0007635| chemosensory behavior TRPV1 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0071502| cellular response to temperature stimulus TRPV1 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPV3;CACNA1H;TRPV2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0001660| fever generation TRPV1 GO:0002024| diet induced thermogenesis TRPV4;TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0048265| response to pain TRPV1;TRPA1 GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPV1;TRPA1 GO:0070588| calcium ion transmembrane transport TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;CHRNA7;TRPV2;OPRM1;CACNA1H;TRPV3 GO:0065009| regulation of molecular function TRPV1 GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GLRA1;TRPA1;CACNA1G GO:0071312| cellular response to alkaloid TRPV1 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0050955| thermoception TRPA1;TRPM8;TRPV1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;GPX1;NAAA;PTGS1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B GO:1990090| TRPV1 GO:0048266| behavioral response to pain TRPV1 GO:0001774| microglial cell activation TRPV1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1 GO:1901594| TRPV1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1 GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:0006816| calcium ion transport TRPV3;CACNA1H;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPM8;TRPV1;CAT GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1 GO:0014047| glutamate secretion TRPV1 GO:0009268| response to pH TRPV1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0002790| peptide secretion TRPV1 GO:0098703| TRPV1 19696:[DB14011 DB03478] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways GO:0031667| response to nutrient levels SOD1;SIRT5 GO:2000378| negative regulation of reactive oxygen species metabolic process SIRT5;VDAC1 19697:[DB14011 DB01481] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01481|1-Testosterone AR common genes common pathways GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport TRPV2;AR;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HMGCR;PTGS2;HTR2A;HTR1A GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0007165| signal transduction AR;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0007548| sex differentiation CYP17A1;AR GO:0008283| cell proliferation GPX1;AR;HTR1A;CYP1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;AR;PPARG;CYP1B1 GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006351| transcription, DNA-dependent AR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B 19698:[DB14011 DB01892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes PTGS1;ALOX5 common pathways GO:0042493| response to drug ABCC2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0006691| leukotriene metabolic process ALOX5;ALOX15;ABCC1 GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0099133| ABCC2;ABCC1 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;PPARG GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;ABCC2;CYP1A1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;PPARG;PLA2G1B GO:0043312| neutrophil degranulation CAT;ALOX5 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCC2;ABCG2;TRPV3;CACNA1H;SLCO1B1;TRPV2 GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:2001300| ALOX5 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1A1;CYP2C9;NR1I2;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCC2;ABCG2;TRPV2 GO:0098869| GSR;GPX1;PTGS1;CAT;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1;ABCC2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9;NR1I2 GO:0007565| female pregnancy IDO1;ABCC2 GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0009408| response to heat SOD1;TRPV3;TRPV2;ABCC2;TRPV1 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS2;CNR2;PTGS1;ALOX5 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2 GO:0006351| transcription, DNA-dependent NR1I2;PPARG GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;PPARG;CYP2C9;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;GLRA3;SLCO1B1;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCC1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0042908| xenobiotic transport ABCG2;NR1I2;ABCC1 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;NR1I2;GPR18;PPARG GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 19699:[DB14011 DB06823] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06823|Tiopronin MPO common genes common pathways GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MPO;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0009612| response to mechanical stimulus MPO;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;MPO;GPX1;CAT GO:0043312| neutrophil degranulation CAT;ALOX5;MPO GO:0032094| response to food OPRM1;MPO;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;MPO;ALOX5;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1 GO:0007568| aging CYP1A1;MPO;CAT;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD GO:0006979| response to oxidative stress GPX1;MPO;PTGS1;CAT;PTGS2;SOD1 GO:0042744| hydrogen peroxide catabolic process CAT;MPO;GPX1 GO:0019430| removal of superoxide radicals SOD1;MPO 19700:[DB14011 DB00369] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways GO:0055085| transmembrane transport TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPV3;CACNA1H;TRPV2 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0001525| angiogenesis TYMP;PTGS2;CYP1B1 GO:0008152| metabolic process TYMP;ACAT1;SMPD1 GO:0098656| SLC22A6;VDAC1 19701:[DB14011 DB01141] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01141|Micafungin COMT;ARSA common genes common pathways GO:0006687| glycosphingolipid metabolic process ARSA;SMPD1 GO:0042493| response to drug ABCG2;COMT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0048265| response to pain COMT;TRPA1;TRPV1 GO:0008210| estrogen metabolic process CYP1B1;COMT GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;COMT;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0007612| learning COMT;VDAC1;PTGS2 GO:0007614| short-term memory CHRNA7;COMT GO:0032259| methylation COMT;CYP1A2 GO:0043312| neutrophil degranulation ALOX5;CAT;ARSA GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1;COMT GO:0051930| regulation of sensory perception of pain COMT;OPRD1;OPRM1 GO:0043627| response to estrogen stimulus COMT;PPARG GO:0032502| developmental process CYP1A1;COMT GO:0048662| negative regulation of smooth muscle cell proliferation COMT;PPARG GO:0007565| female pregnancy COMT;IDO1 GO:0008152| metabolic process ACAT1;ARSA;SMPD1 19702:[DB14011 DB07183] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07183|N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide KDR common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;KDR;TRPV4 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;KDR GO:0008284| positive regulation of cell proliferation KDR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process KDR;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0016032| viral reproduction HTR2A;KDR;VDAC1 GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0001525| angiogenesis PTGS2;CYP1B1;KDR 19703:[DB14011 DB06804] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06804|Nonoxynol-9 PTGS2 common genes PTGS2 common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;TRPV1;IDO1;ALOX15 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRD1;CNR2;PTGS2;OPRM1;HTR2A;CNR1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;CYP2C9;PPARG;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT;CYP1A1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1;CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0071284| cellular response to lead ion PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 19704:[DB14011 DB03968] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03968|1-Methyl-2-Oxy-5,5-Dimethyl Pyrrolidine REN common genes common pathways GO:0008217| regulation of blood pressure PPARG;REN;SOD1;PTGS2;PTGS1 GO:0048469| cell maturation REN;PPARG GO:0010033| response to organic substance TRPA1;REN;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0051591| response to cAMP AANAT;REN GO:0035902| response to immobilization stress CYP1A2;REN;CYP1A1;PPARG GO:0001822| kidney development REN;CAT GO:0032496| response to lipopolysaccharide IDO1;REN;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0042493| response to drug REN;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT 19705:[DB14011 DB08678] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08678|(4-ETHYLPHENYL)SULFAMIC ACID PTPRB common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;PTPRB GO:0001525| angiogenesis PTGS2;CYP1B1;PTPRB 19706:[DB14011 DB01939] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01939|5-Amidino-Benzimidazole PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19707:[DB14011 DB13154] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13154|Parachlorophenol SCN4A;SLCO1B3 common genes common pathways GO:0034220| ion transmembrane transport CHRNA7;GLRA3;GLRB;SCN4A;TRPV1;GLRA1;TRPA1 GO:0055085| transmembrane transport CACNA1I;TRPV4;VDAC1;TRPV1;SCN4A;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLCO1B3 GO:0006936| muscle contraction CACNA1H;SCN4A;GLRA1 GO:0086010| CACNA1I;SCN4A;CACNA1G;CACNA1H GO:0035725| sodium ion transmembrane transport CACNA1H;CACNA1G;SCN4A;CACNA1I GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1I;SCN4A;CACNA1G GO:0006811| ion transport VDAC1;CACNA1I;TRPV4;GLRB;SCN4A;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;SLCO1B3;GLRA3 GO:0034765| regulation of ion transmembrane transport CACNA1I;SCN4A;CACNA1G;CACNA1H 19708:[DB14011 DB00826] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00826|Natamycin CYP3A4 common genes CYP3A4 common pathways GO:0036378| CYP3A4 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 19709:[DB14011 DB06515] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06515|Resiniferatoxin TRPV1 common genes TRPV1 common pathways GO:0009268| response to pH TRPV1 GO:0002790| peptide secretion TRPV1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:0014047| glutamate secretion TRPV1 GO:0051289| protein homotetramerization CAT;TRPV1;TRPM8;TRPA1;CRYZ GO:0009408| response to heat TRPV1;TRPV2;TRPV3;SOD1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0098703| TRPV1 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;NAAA;GPX1;PTGS1 GO:1990090| TRPV1 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0050955| thermoception TRPA1;TRPM8;TRPV1 GO:0071312| cellular response to alkaloid TRPV1 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1 GO:1901594| TRPV1 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1 GO:0048266| behavioral response to pain TRPV1 GO:0001774| microglial cell activation TRPV1 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0065009| regulation of molecular function TRPV1 GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;TRPV3;OPRM1;CACNA1H;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1 GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1 GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0048265| response to pain TRPV1;TRPA1 GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPA1;TRPV1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1 GO:0001660| fever generation TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;TRPV1;GLRB;GLRA1 GO:0002024| diet induced thermogenesis TRPV1;TRPV4 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0055085| transmembrane transport TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;TRPV1;GLRB GO:0071502| cellular response to temperature stimulus TRPV1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0007635| chemosensory behavior TRPV1 GO:0006810| transport TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;HTR2A GO:0071468| cellular response to acidity TRPV1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1 19710:[DB14011 DB07659] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07659|AC-(D)PHE-PRO-BOROHOMOLYS-OH F2 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0061844| F2;PLA2G1B 19711:[DB14011 DB07182] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 19712:[DB14011 DB02008] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0032869| cellular response to insulin stimulus PCK1;PPARG;PLA2G1B GO:0032868| response to insulin stimulus PCK1;AANAT;CAT;TRPV4 GO:0014823| response to activity PCK1;CAT GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;PCK1;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0071320| cellular response to cAMP PCK1;AANAT GO:0007568| aging CYP1A1;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT;PCK1 GO:0071456| cellular response to hypoxia SLC29A1;PCK1;PTGS2;OPRD1 GO:0033993| response to lipid PPARG;PCK1 GO:0042593| glucose homeostasis PCK1;CNR1;TRPV4;PPARG GO:0071356| cellular response to tumor necrosis factor PCK1;TRPV1 GO:0032496| response to lipopolysaccharide PCK1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1 GO:0071300| cellular response to retinoic acid PCK1;PPARG 19713:[DB14011 DB06754] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06754|Danaparoid SERPINC1 common genes common pathways GO:0007584| response to nutrient CNR1;SERPINC1;HMGCR;PPARG GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 GO:0007595| lactation SLC29A1;SERPINC1 19714:[DB14011 DB04474] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04474|1-Anilino-8-Naphthalene Sulfonate murA;S100A7;FABP4;TTR common genes common pathways GO:0006810| transport TRPV2;TTR;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;FABP4 GO:0071356| cellular response to tumor necrosis factor FABP4;TRPV1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;S100A7 GO:0043312| neutrophil degranulation S100A7;ALOX5;CAT;TTR GO:0045087| innate immune response S100A7;PPARG GO:0032496| response to lipopolysaccharide CYP1A1;S100A7;IDO1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0000302| response to reactive oxygen species S100A7;SOD1;GPX1;CAT GO:0050729| positive regulation of inflammatory response TRPV4;FABP4 GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0061844| PLA2G1B;S100A7 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0042572| retinol metabolic process CYP1B1;TTR GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0001525| angiogenesis PTGS2;S100A7;CYP1B1 GO:0050872| white fat cell differentiation FABP4;PPARG 19715:[DB14011 DB07537] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07537|N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;KDR;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0001525| angiogenesis PTGS2;KDR;CYP1B1 GO:0016032| viral reproduction KDR;VDAC1;HTR2A GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 19716:[DB14011 DB07486] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07486|3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline ITGAL common genes common pathways GO:0007155| cell adhesion ITGAL;CYP1B1 GO:0043312| neutrophil degranulation ITGAL;CAT;ALOX5 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;ITGAL;CHRNA7 GO:0006954| inflammatory response CNR2;PTGS2;ITGAL;ALOX5;PTGS1;TRPV1;IDO1;ALOX15 19717:[DB14011 DB13346] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes PTGS1;PTGS2 common pathways GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0070301| cellular response to hydrogen peroxide HDAC6;CYP1B1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0033280| response to vitamin D PTGS2 GO:0009636| response to toxin HDAC6;GPX1;CAT;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0040029| regulation of gene expression, epigenetic GPX1;HDAC6 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS1;ALOX5;PTGS2;CNR2 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:1990776| PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0045598| regulation of fat cell differentiation HDAC6;PPARG GO:0019233| sensory perception of pain OPRD1;PTGS2;CNR2;OPRM1;CNR1;HTR2A;TRPV1;TRPA1 GO:0006351| transcription, DNA-dependent HDAC6;HDAC10;PPARG GO:0010033| response to organic substance HDAC6;SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent HDAC10;HDAC6;PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0098869| GSR;PTGS1;GPX1;CAT;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0097756| PTGS2;HMGCR GO:1903146| VDAC1;HDAC6 GO:0007568| aging HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT;CYP1A1 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0010042| response to manganese ion PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0006355| regulation of transcription, DNA-dependent PPARG;HDAC6;HDAC10 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0070848| response to growth factor stimulus HDAC6;OPRM1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC10;TRPV4;TRPV1;PPARG GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;CYP1A1;IDO1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0071284| cellular response to lead ion PTGS2 19718:[DB14011 DB08129] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08129|(1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 19719:[DB14011 DB00099] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00099|Filgrastim CSF3R;ELANE common genes common pathways GO:0009411| response to UV CAT;ELANE GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ELANE GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CACNA1I;PLA2G1B;SMPD1;CSF3R;GPR18;PPARG GO:0050728| negative regulation of inflammatory response ELANE;CNR2 GO:0048661| positive regulation of smooth muscle cell proliferation ELANE;HMGCR;PTGS2 GO:0030593| neutrophil chemotaxis CSF3R;PLA2G1B GO:0007155| cell adhesion CYP1B1;CSF3R GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;ELANE GO:0043312| neutrophil degranulation ALOX5;CAT;ELANE GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;ELANE;CNR1;PTGS2;CNR2;CYP1A2;OPRM1 GO:0050778| positive regulation of immune response PLA2G1B;ELANE GO:0043406| positive regulation of MAP kinase activity ELANE;HTR2A GO:0006874| cellular calcium ion homeostasis TRPM8;ELANE;TRPV4;CHRNA7;GPR12;HTR2A 19720:[DB14011 DB04326] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04326|Dihydroxyacetone phosphate ALDOA;TPI1;ALDOB;fucA common genes common pathways GO:0007015| actin filament organization PLA2G1B;TRPV4;ALDOA GO:0043312| neutrophil degranulation ALOX5;CAT;ALDOA GO:0002576| platelet degranulation SOD1;ALDOA GO:0046716| muscle cell homeostasis SOD1;ALDOA GO:0051289| protein homotetramerization CAT;ALDOA;CRYZ;TRPA1;TRPV1;TRPM8 GO:0008152| metabolic process ACAT1;TPI1;SMPD1 19721:[DB14011 DB02216] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02216|S-Methylcysteine CTSD;MGMT;FABP1 common genes common pathways GO:0098869| CAT;GPX1;PTGS1;FABP1;PTGS2;GSR GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;FABP1;OPRD1 GO:0015909| long-chain fatty acid transport FABP1;PPARG GO:0042493| response to drug CAT;PTGS2;CYP1A2;MGMT;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;MGMT GO:0043312| neutrophil degranulation CAT;ALOX5;CTSD GO:0032259| methylation MGMT;CYP1A2 GO:0043066| negative regulation of apoptotic process FABP1;PTGS2;HMGCR;MGMT;SOD1;GPX1;CAT GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;MGMT;GSR GO:0070301| cellular response to hydrogen peroxide FABP1;CYP1B1 GO:0009636| response to toxin CYP1A1;CYP1B1;MGMT;GPX1;CAT GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2;MGMT GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;FABP1;CYP1A1;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;FABP1;PTGS2 GO:0045471| response to ethanol CAT;CNR1;SOD1;MGMT;HMGCR;OPRM1 19722:[DB14011 DB03546] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways GO:0010033| response to organic substance CYP1A1;PPARG;GART;TRPA1;CYP1A2;PTGS2;SOD1 GO:0008152| metabolic process SMPD1;GART;ACAT1 19723:[DB14011 DB00325] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00325|Nitroprusside NPR1;CYP1A1 common genes CYP1A1 common pathways GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0035556| intracellular signal transduction PLA2G1B;NPR1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0009692| ethylene metabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:0070988| demethylation CYP1A1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;NPR1 GO:0017143| insecticide metabolic process CYP1A1 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;NPR1;PTGS1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;CYP1A1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0009624| response to nematode CYP1A1 GO:0043010| camera-type eye development CYP1A1 GO:0048662| negative regulation of smooth muscle cell proliferation NPR1;PPARG GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:1900087| CYP1A1 GO:0032502| developmental process CYP1A1 GO:0009308| amine metabolic process CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG;NPR1 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0032094| response to food OPRM1;CYP1A1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP2C9;CYP1A1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0030308| negative regulation of cell growth PPARG;NPR1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;IDO1;CYP1A1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0010041| response to iron(III) ion CYP1A1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;NPR1;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0009611| response to wounding GPX1;CYP1A1 GO:0007568| aging NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT;CYP1A1 19724:[DB14011 DB00287] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00287|Travoprost PTGFR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;PTGFR GO:0032355| response to estradiol stimulus PTGFR;CAT;CYP1A2;PTGS2 GO:0010628| positive regulation of gene expression PTGFR;TRPV4 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2;PTGFR GO:0008284| positive regulation of cell proliferation CHRNA7;PTGFR;HTR1A;HTR2A;PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;PTGFR;GPX1 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;PTGFR;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B 19725:[DB14011 DB01378] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01378|Magnesium cation ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;ATP1A1;TRPV2;CHRNA7 GO:0008217| regulation of blood pressure ATP1A1;SOD1;PTGS2;PTGS1;PPARG GO:0042493| response to drug CAT;CYP1A2;PTGS2;ATP1A1;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG GO:0034220| ion transmembrane transport TRPA1;GLRA1;TRPV1;GLRB;ATP1A1;GLRA3;CHRNA7 GO:0086002| CACNA1G;ATP1A1 19726:[DB14011 DB13931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0016525| negative regulation of angiogenesis ROCK2;PPARG;ROCK1 GO:0043312| neutrophil degranulation ALOX5;CAT;ROCK1 GO:0006915| apoptotic process VDAC1;ROCK1;GPX1 GO:0048511| rhythmic process AANAT;PPARG;ROCK2 GO:0010628| positive regulation of gene expression ROCK2;ROCK1;TRPV4 GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;ROCK2;PPARG;ROCK1 GO:0001934| positive regulation of protein phosphorylation ROCK2;CHRNA7 GO:0043524| negative regulation of neuron apoptosis SOD1;ROCK1 GO:0042752| regulation of circadian rhythm PPARG;ROCK2 GO:1902430| ROCK1;CHRNA7 GO:0035556| intracellular signal transduction ROCK2;PLA2G1B;ROCK1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;ROCK1;CACNA1I;PLA2G1B;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7 GO:0006939| smooth muscle contraction ROCK1;ROCK2;HTR2A 19727:[DB14011 DB04837] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04837|Clofedanol HRH1 common genes common pathways GO:0008542| visual learning HMGCR;HRH1 GO:0006954| inflammatory response ALOX5;PTGS1;HRH1;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0007613| memory CHRNA7;HTR2A;CNR1;HRH1;PTGS2 GO:0007165| signal transduction HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;HRH1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;HRH1;OPRD1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;HRH1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18 19728:[DB14011 DB05161] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ELANE GO:0009411| response to UV ELANE;CAT GO:0019430| removal of superoxide radicals SOD1;MPO GO:0007568| aging SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;MPO;CYP1A1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;MPO;GPX1 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;ELANE;TRPV4;TRPM8 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0043406| positive regulation of MAP kinase activity HTR2A;ELANE GO:0050778| positive regulation of immune response ELANE;PLA2G1B GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;MPO;CYP1A1;IDO1;ELANE GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ELANE GO:0043312| neutrophil degranulation ALOX5;MPO;CAT;PRTN3;ELANE GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;PRTN3;HMGCR;PTGS2;CHRNA7 GO:0009612| response to mechanical stimulus TRPV4;PPARG;MPO GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;MPO;CAT GO:0055114| oxidation-reduction process MPO;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0032094| response to food MPO;OPRM1;CYP1A1 GO:0050728| negative regulation of inflammatory response CNR2;ELANE GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;ELANE 19729:[DB14011 DB07692] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07692|1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine PKM common genes common pathways GO:0032868| response to insulin stimulus CAT;PKM;AANAT;TRPV4 GO:0007584| response to nutrient CNR1;HMGCR;PKM;PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PKM GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPM8;TRPV1;CAT;PKM GO:0043403| skeletal muscle tissue regeneration PKM;GPX1 GO:0001889| liver development CYP1A1;PKM;ACAT1 GO:0008152| metabolic process SMPD1;ACAT1;PKM GO:0001666| response to hypoxia CYP1A1;CAT;PKM;CHRNA7 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2;PKM GO:0031100| organ regeneration PKM;PPARG GO:0043312| neutrophil degranulation ALOX5;PKM;CAT 19730:[DB14011 DB00179] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes ALOX5 common pathways GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;PTGS2;CNR2 GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;CYP2J2;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0008016| regulation of heart contraction CYP2J2;CACNA1H GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 GO:0055114| oxidation-reduction process SOD1;CYP2J2;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;GPX1;PTGS1;CRYZ;CYP2C9;CYP1A1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP2J2 GO:0043312| neutrophil degranulation CAT;ALOX5 GO:2001300| ALOX5 19731:[DB14011 DB08950] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08950|Indoramin ADRA1A common genes common pathways GO:0035556| intracellular signal transduction PLA2G1B;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;ADRA1A;OPRM1;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;ADRA1A GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;ADRA1A;CACNA1I;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;ADRA1A;TRPV4 GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;ADRA1A;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;OPRM1;OPRD1;HTR2A GO:0007202| activation of phospholipase C activity HTR2A;GPR55;ADRA1A GO:0006915| apoptotic process GPX1;ADRA1A;VDAC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18;ADRA1A GO:0007568| aging CYP1A1;ADRA1A;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT 19732:[DB14011 DB07879] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;TRPV1;IDO1;ALOX15;HDAC4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;HDAC4 GO:0007399| nervous system development HDAC4;SMPD1;GLRB GO:0071260| cellular response to mechanical stimulus PTGS2;HDAC4 GO:0006351| transcription, DNA-dependent HDAC4;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;HDAC4;PTGS2;OPRM1 GO:0040029| regulation of gene expression, epigenetic GPX1;HDAC4 GO:0048661| positive regulation of smooth muscle cell proliferation HDAC4;HMGCR;PTGS2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;HDAC4;TRPA1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0006355| regulation of transcription, DNA-dependent PPARG;HDAC4 GO:0045893| positive regulation of transcription, DNA-dependent HDAC4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;HDAC4 GO:0008284| positive regulation of cell proliferation HDAC4;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;HDAC4;PPARG GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC4 GO:0045892| negative regulation of transcription, DNA-dependent HDAC4;PPARG 19733:[DB14011 DB07453] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes CYP1A2 common pathways GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0010468| regulation of gene expression CYP1A2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0032259| methylation CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0022900| electron transport chain IDO1;GSR;CYP1A2 19734:[DB14011 DB02179] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;TTR;TRPV2 GO:0043312| neutrophil degranulation TTR;CAT;ALOX5 19735:[DB14011 DB03747] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways GO:0008152| metabolic process SMPD1;HEXB;ACAT1 GO:0006687| glycosphingolipid metabolic process SMPD1;HEXB GO:0006874| cellular calcium ion homeostasis CHRNA7;HEXB;GPR12;HTR2A;TRPV4;TRPM8 GO:0007605| sensory perception of sound HEXB;GPX1;SOD1 GO:0007626| locomotory behavior OPRM1;SOD1;HEXB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;HEXB GO:0043312| neutrophil degranulation CAT;HEXB;ALOX5 GO:0050905| neuromuscular process HEXB;GLRA1;GLRB 19736:[DB14011 DB06819] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes CYP2D6 common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0051100| negative regulation of binding CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process CYP1B1;ALOX15;CYP2D6;DAGLA;FAAH 19737:[DB14011 DB07668] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 19738:[DB14011 DB07383] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 19739:[DB14011 DB02611] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02611|Balanol Analog 1 PRKACA common genes common pathways GO:0061136| regulation of proteasomal protein catabolic process PRKACA;GPX1 GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0034605| cellular response to heat PRKACA;PTGS2;TRPV1;TRPV4 GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 19740:[DB14011 DB05304] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05304|WX-G250 CA9;IL2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;GPR18;PPARG;IL2 GO:0002376| immune system process IDO1;IL2 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;CA9 GO:0007155| cell adhesion CYP1B1;IL2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation IL2;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;CA9;HTR2A;SOD1;CYP1A2;PTGS2 GO:0050728| negative regulation of inflammatory response IL2;CNR2 GO:0007204| elevation of cytosolic calcium ion concentration IL2;TRPV4;TRPV1;HTR2A;OPRM1 GO:0050729| positive regulation of inflammatory response IL2;TRPV4 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;IL2 GO:0001934| positive regulation of protein phosphorylation IL2;CHRNA7 GO:0006955| immune response IL2;OPRD1;CNR2 GO:0030217| T cell differentiation GPR18;IL2 19741:[DB14011 DB00419] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00419|Miglustat UGCG common genes common pathways GO:0006687| glycosphingolipid metabolic process UGCG;SMPD1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;CYP2C9;PPARG;UGCG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA 19742:[DB14011 DB14528] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14528|Chromium gluconate CYB5A;TF common genes common pathways GO:0006811| ion transport TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;CACNA1H;TF;TRPV3 GO:0001895| retina homeostasis TF;SOD1 GO:0006879| cellular iron ion homeostasis SOD1;TF;ABCG2 GO:0046686| response to cadmium ion CAT;CYB5A GO:0022900| electron transport chain GSR;IDO1;CYP1A2;CYB5A GO:0055114| oxidation-reduction process CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYB5A;PTGS2 GO:0002576| platelet degranulation TF;SOD1 19743:[DB14011 DB01763] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways GO:0072593| reactive oxygen species metabolic process SOD1;NNT GO:0055114| oxidation-reduction process NNT;ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1 19744:[DB14011 DB00155] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0045766| positive regulation of angiogenesis DDAH1;CYP1B1;NOS3;CHRNA7 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;SLC22A6;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0001666| response to hypoxia NOS2;NOS1;CYP1A1;CHRNA7;CAT GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;NOS1;TRPV1 GO:0045429| positive regulation of nitric oxide biosynthetic process ASS1;OPRM1;PTGS2;DDAH2;TRPV1;DDAH1 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0002376| immune system process PADI4;IDO1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3;NOS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NOS1 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT;OTC GO:0006355| regulation of transcription, DNA-dependent PADI4;PPARG GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;NOS2;CRYZ;CYP1A1;CYP2C9;NOS1;CYP1B1;CYP2D6;NOS3;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0007623| circadian rhythm ASS1;AANAT;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide NOS2;CYP1A1;IDO1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development CYP1A2;NOS3 GO:0042311| vasodilation NOS3;NOS1;GPX1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;DDAH2 GO:0070207| protein homotrimerization OTC;TRPM8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NOS1;PLA2G1B GO:0043312| neutrophil degranulation PADI2;ALOX5;CAT GO:0045087| innate immune response PPARG;PADI4 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3;NOS1 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0033555| multicellular organismal response to stress IDO1;NOS1 GO:0006809| nitric oxide biosynthetic process DDAH2;CYP1B1;NOS3;NOS1;NOS2 GO:0032868| response to insulin stimulus AANAT;CAT;OTC;TRPV4 GO:0010043| response to zinc ion AANAT;OTC GO:0008285| negative regulation of cell proliferation CYP1B1;NOS3;PPARG;DDAH1;PTGS2;OPRM1 GO:0098656| VDAC1;SLC22A6 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;NOS3;PPARG GO:1902042| GPX1;NOS3 GO:0045454| cell redox homeostasis GSR;NOS3;NOS2;NOS1;GPX1 GO:0007520| myoblast fusion CACNA1H;NOS1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0031667| response to nutrient levels OTC;SOD1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;NOS1;CYP2C9;CYP2C19 GO:0009408| response to heat NOS1;NOS3;TRPV1;SOD1;TRPV3;TRPV2 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0001889| liver development OTC;ACAT1;CYP1A1 GO:0006351| transcription, DNA-dependent PADI4;PPARG GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure NOS3;NOS2;NOS1;CNR1 GO:0042136| neurotransmitter biosynthetic process NOS1;DAGLA 19745:[DB14011 DB07096] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07096|6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE PARP1 common genes common pathways GO:0006915| apoptotic process VDAC1;GPX1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0034599| cellular response to oxidative stress GPX1;CAT;PARP1;SOD1;GSR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PARP1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PARP1 GO:0010332| response to gamma radiation GPX1;PARP1 GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0071294| cellular response to zinc ion GLRA1;PARP1 19746:[DB14011 DB07272] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07272|N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;MAPK8IP1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;MAPK8 GO:0009411| response to UV CAT;MAPK8 GO:0071260| cellular response to mechanical stimulus PTGS2;MAPK8 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1;MAPK8 GO:0042752| regulation of circadian rhythm PPARG;MAPK8 GO:0048511| rhythmic process MAPK8;AANAT;PPARG GO:0010628| positive regulation of gene expression MAPK8;TRPV4 GO:0043066| negative regulation of apoptotic process GPX1;MAPK8;CAT;PTGS2;HMGCR;SOD1;MAPK8IP1 GO:0051247| positive regulation of protein metabolic process CHRNA7;MAPK8 GO:0006355| regulation of transcription, DNA-dependent MAPK8IP1;PPARG 19747:[DB14011 DB08813] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0006355| regulation of transcription, DNA-dependent MYC;FOS;PPARG GO:0042493| response to drug MYC;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;FOS;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent MYC;PPARG;FOS GO:0007155| cell adhesion SELP;CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;MYC;TRPV4;TRPV1 GO:0034097| response to cytokine stimulus AANAT;PTGS2;FOS GO:0035902| response to immobilization stress FOS;CYP1A1;PPARG;CYP1A2 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;MYC GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;MYC;PPARG;FOS GO:0070848| response to growth factor stimulus MYC;OPRM1 GO:0002576| platelet degranulation SELP;SOD1 GO:0009612| response to mechanical stimulus TRPV4;FOS;PPARG GO:0043066| negative regulation of apoptotic process MYC;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;SELP;FOS;CYP1A1;IDO1 GO:0009416| response to light stimulus FOS;AANAT GO:0010628| positive regulation of gene expression MYC;TRPV4 GO:0051591| response to cAMP AANAT;FOS GO:0010468| regulation of gene expression MYC;CYP1A2 GO:0071456| cellular response to hypoxia MYC;PTGS2;OPRD1;SLC29A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade SELP;CAT GO:0007568| aging FOS;CYP1A1;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT GO:0007595| lactation SLC29A1;SERPINC1 GO:0006879| cellular iron ion homeostasis MYC;ABCG2;SOD1 GO:0006954| inflammatory response FOS;TRPV1;ALOX15;IDO1;CNR2;PTGS2;SELP;ALOX5;PTGS1 GO:0007565| female pregnancy FOS;IDO1 GO:0007399| nervous system development GLRB;FOS;SMPD1 GO:0009409| response to cold TRPM8;PPARG;TRPA1;FOS GO:0071277| cellular response to calcium ion ALOX15;FOS GO:0006351| transcription, DNA-dependent PPARG;MYC GO:0030431| sleep SLC29A1;HTR2A;CACNA1I;FOS GO:0006357| regulation of transcription from RNA polymerase II promoter MYC;FOS;PPARG GO:0007584| response to nutrient CNR1;SERPINC1;HMGCR;PPARG GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;FOS GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;MYC GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0014070| response to organic cyclic compound TRPA1;FOS;PPARG;CYP1A1;PTGS2;CYP1A2;ACAT1;AANAT GO:0009636| response to toxin CYP1A1;FOS;CYP1B1;GPX1;CAT GO:0010332| response to gamma radiation GPX1;MYC GO:0051412| response to corticosterone stimulus AANAT;FOS GO:0034644| cellular response to UV PTGS2;MYC GO:0032870| cellular response to hormone stimulus FOS;CACNA1H 19748:[DB14011 DB01091] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01091|Butenafine SQLE common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process SQLE;HMGCR GO:0010033| response to organic substance SQLE;SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1;SQLE;CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1 GO:0008203| cholesterol metabolic process HMGCR;CAT;SQLE GO:0006695| cholesterol biosynthetic process SQLE;HMGCR GO:0006725| cellular aromatic compound metabolic process SQLE;CYP1A2;CYP1B1 GO:0016126| sterol biosynthetic process HMGCR;SQLE 19749:[DB14011 DB07003] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;GSR;NOS2 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;NOS2;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0032496| response to lipopolysaccharide CYP1A1;NOS2;IDO1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation PTGS2;PTGS1;NOS2 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 19750:[DB14011 DB00055] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0071470| cellular response to osmotic stress SERPINB6;TRPV4 GO:0010628| positive regulation of gene expression PF4;TRPV4 GO:0007283| spermatogenesis SERPINA5;SOD1;CNR1 GO:0051591| response to cAMP THBD;AANAT GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;SERPINE1 GO:0007605| sensory perception of sound GPX1;SOD1;SERPINB6 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;PF4;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0030595| leukocyte chemotaxis CNR2;PF4 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0016525| negative regulation of angiogenesis PPARG;PF4 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1;SERPINE1 GO:0055114| oxidation-reduction process CP;ALOX5;PTGS1;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;F8;CYP2C9;CYP1A1;CRYZ GO:0002576| platelet degranulation PROS1;SOD1;SERPINE1;F8;PF4;F5 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;PLA2G1B;PPARG;PF4 GO:0043312| neutrophil degranulation SERPINB6;CAT;ALOX5 GO:0042127| regulation of cell proliferation PF4;PTGS1;PTGS2 GO:0007623| circadian rhythm AANAT;SERPINE1 GO:0032496| response to lipopolysaccharide THBD;CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1;PF4 GO:0030336| negative regulation of cell migration CYP1B1;SERPINE1 GO:0061844| PF4;F2;PLA2G1B GO:1902042| GPX1;SERPINE1 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;CP;CHRNA7 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;THBD;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0050729| positive regulation of inflammatory response SERPINE1;TRPV4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;PF4 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;PF4;ALOX15;IDO1;TRPV1 GO:0006955| immune response OPRD1;CNR2;PF4 GO:0006879| cellular iron ion homeostasis CP;SOD1;ABCG2 GO:0007565| female pregnancy IDO1;THBD GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061045| negative regulation of wound healing SERPINE1;HMGCR GO:0001525| angiogenesis CYP1B1;PTGS2;SERPINE1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 19751:[DB14011 DB12340] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways GO:0072593| reactive oxygen species metabolic process SOD1;BCL2 GO:0051384| response to glucocorticoid stimulus BAD;BCL2;PTGS2 GO:0010332| response to gamma radiation GPX1;BCL2 GO:0009725| response to hormone stimulus BAD;ACAT1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;OPRD1;PTGS2 GO:0009636| response to toxin CYP1A1;CYP1B1;BCL2;CAT;GPX1 GO:0014070| response to organic cyclic compound BAD;PTGS2;CYP1A2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0006919| activation of caspase activity PPARG;BAD GO:0008283| cell proliferation CYP1A1;GPX1;BCL2;BAD;HTR1A GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;BCL2 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;BCL2 GO:0009791| post-embryonic development CYP1A2;BCL2 GO:0030336| negative regulation of cell migration CYP1B1;BCL2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;BCL2;OPRM1;PTGS2 GO:0001662| behavioral fear response VDAC1;HTR1A;BCL2 GO:0051592| response to calcium ion AANAT;BAD GO:0045471| response to ethanol BAD;CNR1;SOD1;HMGCR;OPRM1;CAT GO:0042542| response to hydrogen peroxide TRPA1;BCL2;SOD1;BAD;GPX1;CAT GO:0009314| response to radiation PTGS2;OPRM1;BCL2;CAT GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;BAD;CNR1;SOD1;PTGS2 GO:0071260| cellular response to mechanical stimulus BAD;PTGS2 GO:0001503| ossification BCL2;ALOX15 GO:0043524| negative regulation of neuron apoptosis SOD1;BCL2 GO:0007565| female pregnancy IDO1;BCL2 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;BCL2;GPX1 GO:0030217| T cell differentiation BCL2;GPR18 GO:0051924| regulation of calcium ion transport OPRD1;BCL2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;BAD;CAT GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1;BCL2;BAD GO:0010468| regulation of gene expression CYP1A2;BCL2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;BCL2;PTGS2;SOD1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;BCL2;HTR2A;GPR12;CHRNA7 GO:0048538| thymus development SOD1;BCL2 GO:0042593| glucose homeostasis TRPV4;PPARG;BAD;CNR1 GO:0043085| positive regulation of catalytic activity SOD1;BCL2 GO:0043200| response to amino acid stimulus GLRB;BAD;GLRA3 GO:0001541| ovarian follicle development BCL2;SOD1 GO:0006915| apoptotic process VDAC1;BAD;BCL2;BCL2L2;GPX1 GO:0055085| transmembrane transport TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;BCL2;CACNA1H GO:0007283| spermatogenesis CNR1;SOD1;BAD;BCL2L2 GO:0001666| response to hypoxia BAD;CAT;CHRNA7;CYP1A1 GO:0001657| ureteric bud development BCL2;CAT GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;BAD;TRPA1;PPARG;CYP1A1 GO:0030308| negative regulation of cell growth PPARG;BCL2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;BCL2;SOD1;GPX1;CAT;BCL2L2 GO:0001822| kidney development CAT;BCL2 GO:0008284| positive regulation of cell proliferation BCL2;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0034097| response to cytokine stimulus AANAT;BCL2;PTGS2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;BAD;CYP1A2;PTGS2;BCL2 GO:0007569| cell aging BCL2;SOD1 GO:0035094| response to nicotine CHRNA7;CNR1;BCL2 GO:0007015| actin filament organization PLA2G1B;TRPV4;BCL2 19752:[DB14011 DB04606] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F7;GPX1 GO:0007623| circadian rhythm F7;AANAT GO:0001666| response to hypoxia CYP1A1;F7;CAT;CHRNA7 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;F7 GO:0031100| organ regeneration PPARG;F7 GO:0031667| response to nutrient levels SOD1;F7 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;F7;PTGS2;CYP1A2;AANAT;ACAT1 GO:0043627| response to estrogen stimulus F7;PPARG GO:0009725| response to hormone stimulus ACAT1;F7 19753:[DB14011 DB00524] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00524|Metolazone SLC12A3 common genes common pathways GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SLC12A3;CACNA1H GO:1902476| GLRA3;SLC12A3;GLRA1;GLRB GO:0006811| ion transport TRPV2;SLC12A3;CHRNA7;CACNA1H;TRPV3;GLRA3;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0006810| transport TRPV2;SLC12A3;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;SLC12A3;CACNA1H;TRPV3 19754:[DB14011 DB04890] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04890|Bepotastine HRH1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HRH1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;HRH1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PPARG;GPR18 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;CNR2;PTGS2;HRH1;ALOX5;PTGS1 GO:0008542| visual learning HMGCR;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;HRH1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0007613| memory CHRNA7;PTGS2;HRH1;CNR1;HTR2A 19755:[DB14011 DB03661] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03661|Cysteinesulfonic Acid CTSL;def;GLIPR2;def;fabH;PTPN1;CDC25B common genes common pathways GO:0034976| response to endoplasmic reticulum stress ALOX15;PTPN1 GO:0008284| positive regulation of cell proliferation CDC25B;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0031532| actin cytoskeleton reorganization PTPN1;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;GLIPR2;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;PTPN1 19756:[DB14011 DB07992] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways GO:0098869| ALB;GSR;PTGS1;GPX1;CAT;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0002576| platelet degranulation SOD1;ALB GO:0001895| retina homeostasis SOD1;ALB 19757:[DB14011 DB03101] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03101|Ribose-1-Phosphate PNP common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;PNP GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;PNP;TRPA1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0006955| immune response PNP;OPRD1;CNR2 GO:0006195| purine nucleotide catabolic process GPX1;PNP 19758:[DB14011 DB08055] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;LCK;TRPV1 GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;LCK;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;LCK GO:0042127| regulation of cell proliferation PTGS2;PTGS1;LCK GO:0045087| innate immune response LCK;PPARG GO:0006919| activation of caspase activity PPARG;LCK GO:0016032| viral reproduction HTR2A;VDAC1;LCK GO:0030217| T cell differentiation LCK;GPR18 19759:[DB14011 DB01776] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01776|M-Cresol INS common genes common pathways GO:0042593| glucose homeostasis CNR1;INS;PPARG;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;INS;TRPV1 GO:0097756| PTGS2;HMGCR;INS GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade INS;CAT GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;INS;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0015758| glucose transport PLA2G1B;INS GO:0032460| negative regulation of protein oligomerization INS;OPRD1 GO:0010628| positive regulation of gene expression TRPV4;INS GO:0002674| negative regulation of acute inflammatory response PPARG;INS GO:0008284| positive regulation of cell proliferation INS;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0042060| wound healing ALOX15;INS;OPRM1 GO:0051897| positive regulation of protein kinase B signaling cascade INS;GPX1 GO:1902176| GPX1;INS GO:0006355| regulation of transcription, DNA-dependent PPARG;INS GO:0090336| positive regulation of brown fat cell differentiation PTGS2;INS GO:1900273| CHRNA7;INS GO:0050890| cognition CHRNA7;INS GO:0045740| positive regulation of DNA replication PLA2G1B;INS GO:0045821| positive regulation of glycolysis HTR2A;INS GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;INS GO:0051092| positive regulation of NF-kappaB transcription factor activity INS;CAT;PLA2G1B 19760:[DB14011 DB03594] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03594|1,2,4-Triazole CA2 common genes common pathways GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CA2;TRPA1;PPARG;CYP1A1 19761:[DB14011 DB09087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09087|Potassium alum ALB common genes common pathways GO:0001895| retina homeostasis ALB;SOD1 GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB 19762:[DB14011 DB09121] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0042752| regulation of circadian rhythm ADCY1;PPARG GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADCY2;CNR1 GO:0035556| intracellular signal transduction ADCY5;PLA2G1B;ADCY2;ADCY1 GO:0071277| cellular response to calcium ion ADCY1;ALOX15 GO:0007165| signal transduction CACNA1I;ADCY2;PLA2G1B;ADCY1;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0010226| response to lithium ion PTGS2;ADCY1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;ADCY5;TRPV4;TRPV1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY5;OPRD1;OPRM1;ADCY1;ADCY2 GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ADCY1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0007626| locomotory behavior SOD1;OPRM1;ADCY5 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;ADCY5 GO:0007623| circadian rhythm ADCY1;AANAT GO:0048511| rhythmic process PPARG;ADCY1;AANAT GO:0007186| G-protein coupled receptor signaling pathway ADCY2;ADCY1;PPARG;GPR18;ADCY5;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 19763:[DB14011 DB07342] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0035094| response to nicotine HMOX1;CNR1;CHRNA7 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;HMOX1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;HMOX1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;PTGS1;GPX1 GO:0001666| response to hypoxia HMOX1;CAT;CHRNA7;CYP1A1 GO:0008219| cell death HMOX1;HTR2A GO:0045766| positive regulation of angiogenesis CHRNA7;HMOX1;CYP1B1 GO:0006915| apoptotic process VDAC1;HMOX1;GPX1 GO:0051260| protein homooligomerization ACAT1;GLRA3;HMOX1;GLRA1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;HMOX1 GO:0071456| cellular response to hypoxia SLC29A1;HMOX1;OPRD1;PTGS2 GO:0034605| cellular response to heat HMOX1;PTGS2;TRPV4;TRPV1 GO:1904706| PPARG;HMOX1 GO:0006879| cellular iron ion homeostasis SOD1;HMOX1;ABCG2 GO:0043524| negative regulation of neuron apoptosis SOD1;HMOX1 GO:0042542| response to hydrogen peroxide HMOX1;SOD1;GPX1;CAT;TRPA1 GO:0043065| positive regulation of apoptotic process PTGS2;HMOX1;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0035556| intracellular signal transduction HMOX1;PLA2G1B GO:0001525| angiogenesis CYP1B1;PTGS2;HMOX1 GO:1902042| GPX1;HMOX1 GO:0043627| response to estrogen stimulus PPARG;HMOX1 GO:0008217| regulation of blood pressure PTGS1;SOD1;HMOX1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;HMOX1 GO:0071276| cellular response to cadmium ion SOD1;HMOX1;CYP1A2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;HMOX1 19764:[DB14011 DB04377] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04377|Meglutol HMGCR common genes HMGCR common pathways GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0010664| negative regulation of striated muscle cell apoptosis HMGCR GO:0048643| positive regulation of skeletal muscle tissue development HMGCR GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1 GO:0006743| ubiquinone metabolic process HMGCR GO:0015936| coenzyme A metabolic process HMGCR;ACAT1 GO:0008542| visual learning HMGCR GO:0045445| myoblast differentiation HMGCR GO:0016126| sterol biosynthetic process HMGCR GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0061045| negative regulation of wound healing HMGCR GO:0045471| response to ethanol CNR1;SOD1;OPRM1;HMGCR;CAT GO:0051262| protein tetramerization CAT;HMGCR GO:0043407| negative regulation of MAP kinase activity SMPD1;HMGCR GO:0008299| isoprenoid biosynthetic process HMGCR GO:0045540| regulation of cholesterol biosynthetic process HMGCR GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;ALOX15 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0007568| aging CYP1A1;CAT;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR GO:0097756| PTGS2;HMGCR GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0006694| steroid biosynthetic process HMGCR;CYP17A1 GO:0010666| positive regulation of cardiac muscle cell apoptosis HMGCR GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0008203| cholesterol metabolic process CAT;HMGCR GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR GO:0006695| cholesterol biosynthetic process HMGCR GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR 19765:[DB14011 DB08206] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0006810| transport ABCC1;ABCG2;CACNA1I;TRPV1;TTR;TRPV2 19766:[DB14011 DB02147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways GO:0006631| fatty acid metabolic process ALOX15;PTGS1;C3;PTGS2 GO:0045087| innate immune response C3;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;C3 GO:0045766| positive regulation of angiogenesis CYP1B1;C3;CHRNA7 GO:0002376| immune system process IDO1;C3 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;C3;HTR2A;GPR12;CNR1;GPR55;HTR1A;GPR18;PPARG GO:0006954| inflammatory response PTGS2;CNR2;C3;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0006955| immune response C3;OPRD1;CNR2 GO:0001934| positive regulation of protein phosphorylation C3;CHRNA7 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;C3;PTGS1;NAAA;GPX1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2;C3 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;GPR12;CNR1;C3;HTR2A;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG 19767:[DB14011 DB04405] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04405|2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid MMP12 common genes common pathways GO:0042060| wound healing ALOX15;OPRM1;MMP12 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;MMP12 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;PPARG;PLA2G1B GO:0010628| positive regulation of gene expression MMP12;TRPV4 19768:[DB14011 DB04106] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04106|Fotemustine TXNRD1 common genes common pathways GO:0098869| GSR;PTGS2;CAT;PTGS1;GPX1;TXNRD1 GO:0034599| cellular response to oxidative stress GSR;SOD1;CAT;TXNRD1;GPX1 GO:0022900| electron transport chain CYP1A2;TXNRD1;GSR;IDO1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;PTGS1;GPX1;TXNRD1 GO:0045454| cell redox homeostasis GSR;GPX1;TXNRD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;TXNRD1;CNR1;HMGCR GO:0007165| signal transduction CHRNA7;TXNRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;TXNRD1 GO:0015949| nucleobase-containing small molecule interconversion TXNRD1;GSR 19769:[DB14011 DB03042] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03042|5-Phosphoarabinonic Acid GPI common genes common pathways GO:0043524| negative regulation of neuron apoptosis GPI;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;PTGS2;GPX1 GO:0001525| angiogenesis PTGS2;GPI;CYP1B1 GO:0046686| response to cadmium ion GPI;CAT GO:0042593| glucose homeostasis CNR1;TRPV4;GPI;PPARG GO:0032355| response to estradiol stimulus GPI;CAT;PTGS2;CYP1A2 GO:0043278| response to morphine OPRM1;CNR1;GPI GO:0035902| response to immobilization stress CYP1A2;GPI;PPARG;CYP1A1 GO:0043312| neutrophil degranulation GPI;CAT;ALOX5 GO:0007611| learning or memory GPI;CNR1;CHRNA7 19770:[DB14011 DB00032] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00032|Menotropins FSHR;LHCGR common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LHCGR;HTR2A;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;FSHR;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;LHCGR;GPR55;HTR1A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FSHR;CAT GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;FSHR;CHRNA7 GO:0007283| spermatogenesis CNR1;SOD1;FSHR GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR2;OPRM1;OPRD1;LHCGR;CNR1 GO:0050890| cognition CHRNA7;LHCGR GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;FSHR;GPR12;CNR1;HTR2A;GPR55;HTR1A;LHCGR;OPRD1;OPRM1;CNR2 19771:[DB14011 DB03104] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03104|RU82129 SRC common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0002376| immune system process IDO1;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;SRC;CHRNA7;TRPV4;ALOX15 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0009615| response to virus CYP1A1;SRC GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;SRC;GPX1 GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0042493| response to drug SRC;CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0016236| macroautophagy SRC;VDAC1 GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7;SRC GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0045453| bone resorption GPR55;SRC GO:0008283| cell proliferation CYP1A1;GPX1;SRC;HTR1A GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process SRC;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0042542| response to hydrogen peroxide CAT;SRC;GPX1;SOD1;TRPA1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0016032| viral reproduction VDAC1;HTR2A;SRC 19772:[DB14011 DB01672] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01672|2,3-Dihydroxy-Benzoic Acid LCN2 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;LCN2;CAT GO:0045087| innate immune response PPARG;LCN2 GO:0002376| immune system process IDO1;LCN2 GO:0006915| apoptotic process GPX1;LCN2;VDAC1 GO:0006879| cellular iron ion homeostasis ABCG2;LCN2;SOD1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;LCN2;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8 19773:[DB14011 DB11652] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11652|Tucatinib ERBB2 common genes common pathways GO:0042060| wound healing ALOX15;OPRM1;ERBB2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ERBB2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;ERBB2 GO:0071363| cellular response to growth factor stimulus CAT;ERBB2;OPRD1;TRPV1 GO:0010628| positive regulation of gene expression TRPV4;ERBB2 GO:0043406| positive regulation of MAP kinase activity ERBB2;HTR2A GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ERBB2 GO:0006351| transcription, DNA-dependent ERBB2;PPARG GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ERBB2 GO:0007399| nervous system development ERBB2;SMPD1;GLRB GO:0007507| heart development PPARG;ERBB2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ERBB2 GO:0014065| phosphatidylinositol 3-kinase cascade ERBB2;HTR2A GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;ERBB2;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0008283| cell proliferation CYP1A1;HTR1A;ERBB2;GPX1 19774:[DB14011 DB02141] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02141|S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0030324| lung development NOS3;CYP1A2 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0042311| vasodilation NOS3;GPX1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;NOS3;CYP2C19;GSR;IDO1;CYP1A1;CYP2C9;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0001525| angiogenesis PTGS2;NOS3;CYP1B1 GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0009408| response to heat NOS3;TRPV1;SOD1;TRPV3;TRPV2 GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:1902042| GPX1;NOS3 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1;NOS3 19775:[DB14011 DB08615] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion ACHE;CYP1B1 GO:0008283| cell proliferation ACHE;HTR1A;GPX1;CYP1A1 GO:0007399| nervous system development ACHE;SMPD1;GLRB GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE 19776:[DB14011 DB13158] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13158|Clobetasone NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0007165| signal transduction CHRNA7;NR3C1;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;NAAA;PTGS1;GPX1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR3C1 19777:[DB14011 DB04112] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04112|1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide PLA2G2A common genes common pathways GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G2A;PLA2G1B GO:0016042| lipid catabolic process PLA2G2A;DAGLA;PLA2G1B;NAPEPLD GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;PLA2G2A;ALOX15;TRPV4 GO:0036152| PLA2G1B;PLA2G2A GO:0050830| defense response to Gram-positive bacterium PLA2G2A;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G2A;PLA2G1B GO:0036151| PLA2G2A;PLA2G1B GO:0036150| PLA2G2A;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2A GO:0050729| positive regulation of inflammatory response TRPV4;PLA2G2A GO:0036148| PLA2G1B;PLA2G2A GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;PLA2G2A;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1 GO:0036149| PLA2G2A;PLA2G1B 19778:[DB14011 DB02097] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02097|Cytidine UCK2 common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;UCK2 19779:[DB14011 DB14042] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14042|Galcanezumab CALCA;CALCB common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;CALCB;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0061844| PLA2G1B;CALCA GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;CALCA GO:0045776| negative regulation of blood pressure CNR1;CALCA GO:0007186| G-protein coupled receptor signaling pathway CALCB;PPARG;CALCA;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0006874| cellular calcium ion homeostasis TRPV4;CALCB;TRPM8;CHRNA7;GPR12;HTR2A GO:0045671| negative regulation of osteoclast differentiation CALCA;GPR55 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger CALCA;GPR18;GPR55 GO:0043542| endothelial cell migration CALCA;CYP1B1 GO:0045087| innate immune response PPARG;CALCA GO:0019731| antibacterial humoral response PLA2G1B;CALCA GO:0050830| defense response to Gram-positive bacterium CALCA;PLA2G1B 19780:[DB14011 DB05416] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0071456| cellular response to hypoxia PPARD;OPRD1;PTGS2;SLC29A1 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PPARD;CAT GO:0046697| decidualization PTGS2;PPARD GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0006915| apoptotic process PPARD;GPX1;VDAC1 GO:0001666| response to hypoxia CHRNA7;CAT;PPARA;CYP1A1 GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;PPARD;SOD1;PPARG;CYP1A1;TRPA1 GO:0015758| glucose transport PLA2G1B;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0042127| regulation of cell proliferation PPARD;PTGS2;PTGS1 GO:0042060| wound healing ALOX15;PPARA;PPARD;OPRM1 GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PPARD;PTGS2;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;PPARD;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARD;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD;PPARA GO:0006631| fatty acid metabolic process PTGS1;PPARA;PTGS2;ALOX15 GO:0050728| negative regulation of inflammatory response PPARA;CNR2;PPARD GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD;PPARA GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0033189| response to vitamin A CAT;PPARD;PPARG;CYP1A1 GO:0007566| embryo implantation PPARD;PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;PPARA;CNR1;HMGCR GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;PPARD GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0032868| response to insulin stimulus PPARA;CAT;AANAT;TRPV4 GO:0045600| positive regulation of fat cell differentiation PPARD;HTR2A;PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0060612| adipose tissue development ACAT1;PPARD GO:0019395| fatty acid oxidation PPARG;PPARD GO:0001890| placenta development SOD1;PPARD;PPARG GO:0014823| response to activity CAT;PPARD GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARA;PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARD;PPARG GO:0007507| heart development PPARA;PPARD;PPARG GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;PPARA;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;PPARD;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA 19781:[DB14011 DB05993] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05993|PRX-07034 HTR6 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18;HTR6 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR2;OPRM1;OPRD1;CNR1;HTR6 GO:0007165| signal transduction HTR6;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0007268| synaptic transmission HTR6;VDAC1;GLRB;GLRA1;CACNA1G;HTR2A;GLRA3;OPRM1;OPRD1 19782:[DB14011 DB13914] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13914|Volixibat SLC10A2 common genes common pathways GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;SLC10A2;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;CACNA1I;TRPV4;VDAC1;TRPV1;SLC10A2;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0006810| transport ABCC1;SLC10A2;TRPV1;CACNA1I;ABCG2;TRPV2 19783:[DB14011 DB03317] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes CYP2C9 common pathways GO:0006915| apoptotic process CYCS;GPX1;VDAC1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYCS;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0034599| cellular response to oxidative stress GSR;CYCS;SOD1;GPX1;CAT GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0045333| cellular respiration CYP1A2;CYCS GO:0019627| urea metabolic process CYP2C9 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0043603| cellular amide metabolic process CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 19784:[DB14011 DB04027] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04027|D-Arginine CKM common genes common pathways 19785:[DB14011 DB06433] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;RRM1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0015949| nucleobase-containing small molecule interconversion RRM1;GSR GO:0008152| metabolic process SMPD1;RRM1;ACAT1;TYMP GO:0001525| angiogenesis TYMP;PTGS2;CYP1B1 19786:[DB14011 DB04516] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;ISYNA1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG 19787:[DB14011 DB00548] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0018894| dibenzo-p-dioxin metabolic process SRD5A2;CYP1A2;CYP1A1 GO:0006694| steroid biosynthetic process CYP17A1;SRD5A2;HMGCR GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;SRD5A2;CYP3A4;HMGCR;CYP1A2;CYP3A7;AKR1D1;PTGS2;TYR;CAT;PTGS1;ALOX5;GPX1 GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;SRD5A2;CAT GO:0048538| thymus development SOD1;TYR GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;HMGCR;CYP3A7;AKR1D1;CYP1A2;SRD5A2;CYP3A4 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;SRD5A2;CYP1A2;PTGS2 GO:0016042| lipid catabolic process NAPEPLD;AKR1D1;DAGLA;PLA2G1B GO:0051591| response to cAMP AANAT;TYR GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;SRD5A2;AKR1D1;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0006706| steroid catabolic process CYP1A2;SRD5A2;CYP3A4 GO:0008152| metabolic process SMPD1;TYR;ACAT1 GO:0042448| progesterone metabolic process SRD5A2;CYP17A1 GO:0008209| androgen metabolic process AKR1D1;SRD5A2;CYP3A4 GO:0031667| response to nutrient levels SRD5A2;SOD1 GO:0007601| visual perception TYR;GLRA1;CRYZ;GLRB;CYP1B1 GO:0043434| response to peptide hormone stimulus TRPV1;SRD5A2 GO:0006702| androgen biosynthetic process SRD5A2;CYP17A1 GO:0007548| sex differentiation SRD5A2;CYP17A1 GO:0033280| response to vitamin D TYR;PTGS2 GO:0008283| cell proliferation CYP1A1;TYR;GPX1;HTR1A GO:0009411| response to UV CAT;TYR GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;SRD5A2;PTGS2;CYP1A2 19788:[DB14011 DB03109] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03109|N-Acetyl-D-Allosamine CHIT1 common genes common pathways GO:0006955| immune response CNR2;OPRD1;CHIT1 GO:0008152| metabolic process ACAT1;CHIT1;SMPD1 GO:0043312| neutrophil degranulation CHIT1;ALOX5;CAT 19789:[DB14011 DB06727] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06727|Sparteine CYP2D6 common genes CYP2D6 common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;FAAH GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0051100| negative regulation of binding CYP2D6 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;NAAA;PTGS1;GPX1;PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 19790:[DB14011 DB00406] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00406|Gentian violet cation SLC22A1 common genes common pathways GO:0051260| protein homooligomerization SLC22A1;GLRA1;GLRA3;ACAT1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;SLC22A1;CACNA1G;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0006812| cation transport TRPM8;SLC22A1 GO:0006855| drug transmembrane transport ABCG2;SLC22A1;ABCC1 GO:0006811| ion transport GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;SLC22A1;TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1 19791:[DB14011 DB09401] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCL2 GO:0072593| reactive oxygen species metabolic process BCL2;SOD1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;BCL2L1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BCL2;OPRD1 GO:0010332| response to gamma radiation GPX1;BCL2 GO:0051881| regulation of mitochondrial membrane potential BCL2L1;SOD1;BCL2;OPRD1 GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;VDAC1 GO:0008283| cell proliferation GPX1;HTR1A;BCL2;BCL2L1;CYP1A1 GO:0009636| response to toxin BCL2;CAT;GPX1;CYP1A1;CYP1B1 GO:1902042| BCL2L1;GPX1 GO:0001662| behavioral fear response VDAC1;HTR1A;BCL2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCL2;CYP1B1;PPARG GO:0009791| post-embryonic development BCL2;CYP1A2 GO:0030336| negative regulation of cell migration CYP1B1;BCL2 GO:0001503| ossification BCL2;ALOX15 GO:0043065| positive regulation of apoptotic process IDO1;BCL2L1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0071312| cellular response to alkaloid TRPV1;BCL2L1 GO:0009314| response to radiation BCL2L1;CAT;OPRM1;PTGS2;BCL2 GO:0042542| response to hydrogen peroxide GPX1;CAT;BCL2;SOD1;TRPA1 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;GPX1;BCL2 GO:0007565| female pregnancy BCL2;IDO1 GO:0043524| negative regulation of neuron apoptosis BCL2L1;SOD1;BCL2 GO:0051924| regulation of calcium ion transport BCL2;OPRD1 GO:0030217| T cell differentiation GPR18;BCL2 GO:0010468| regulation of gene expression BCL2;CYP1A2 GO:0071456| cellular response to hypoxia SLC29A1;BCL2;OPRD1;PTGS2 GO:0043085| positive regulation of catalytic activity SOD1;BCL2 GO:0048538| thymus development SOD1;BCL2 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;BCL2;CHRNA7;TRPM8;TRPV4 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;BCL2 GO:0055085| transmembrane transport TRPV2;TRPV3;BCL2;CACNA1H;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0006915| apoptotic process MCL1;GPX1;BCL2;VDAC1;BCL2L1 GO:0001541| ovarian follicle development BCL2;SOD1;BCL2L1 GO:0001657| ureteric bud development BCL2;CAT GO:0007283| spermatogenesis BCL2L1;CNR1;SOD1 GO:0071230| cellular response to amino acid stimulus BCL2L1;GLRA1 GO:0030308| negative regulation of cell growth PPARG;BCL2 GO:0034097| response to cytokine stimulus BCL2L1;PTGS2;BCL2;MCL1;AANAT GO:0008284| positive regulation of cell proliferation BCL2L1;CHRNA7;BCL2;HMGCR;PTGS2;HTR2A;HTR1A GO:0009615| response to virus CYP1A1;BCL2L1 GO:0001822| kidney development CAT;BCL2 GO:0043066| negative regulation of apoptotic process BCL2L1;PTGS2;BCL2;HMGCR;SOD1;GPX1;MCL1;CAT GO:0007569| cell aging BCL2;SOD1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CAT;BCL2;PTGS2;CYP1A2;SOD1;HTR2A GO:0007015| actin filament organization PLA2G1B;TRPV4;BCL2 GO:0035094| response to nicotine CNR1;BCL2;CHRNA7 19792:[DB14011 DB01818] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01818|O3-Sulfonylgalactose MBL2 common genes common pathways GO:0002376| immune system process IDO1;MBL2 GO:0006979| response to oxidative stress MBL2;SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0045087| innate immune response MBL2;PPARG GO:0050830| defense response to Gram-positive bacterium PLA2G1B;MBL2 19793:[DB14011 DB05309] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05309|TP-508 FGF4 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGF4 GO:0043066| negative regulation of apoptotic process FGF4;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;FGF4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;FGF4;PPARG GO:0010628| positive regulation of gene expression FGF4;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;FGF4;ALOX15 GO:0010468| regulation of gene expression FGF4;CYP1A2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;FGF4 GO:0051781| positive regulation of cell division CAT;FGF4 GO:0065009| regulation of molecular function FGF4;TRPV1 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;FGF4;SMPD1;PPARG;GPR18 19794:[DB14011 DB03621] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03621|L-709,587 FKBP1A common genes common pathways GO:0051209| release of sequestered calcium ion into cytosol TRPA1;FKBP1A;TRPV1;HTR2A GO:0006936| muscle contraction FKBP1A;GLRA1;CACNA1H GO:0031000| response to caffeine PPARG;FKBP1A GO:1902991| FKBP1A;CHRNA7 GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3;TRPV1;TRPV4;CACNA1I;FKBP1A;TRPM8;CACNA1G;TRPA1 19795:[DB14011 DB12212] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12212|Landiolol CYP2D6 common genes CYP2D6 common pathways GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1A1;CYP2C9;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0051100| negative regulation of binding CYP2D6 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 19796:[DB14011 DB06929] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06929|1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;F2;PPARG;GPR18 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT 19797:[DB14011 DB05050] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05050|ADL5859 OPRD1 common genes OPRD1 common pathways GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0038003| opioid receptor signaling pathway OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRD1;OPRM1;GLRB;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A GO:0097237| OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0008344| adult locomotory behavior OPRD1 GO:0042755| eating behavior OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0006955| immune response CNR2;OPRD1 GO:0007268| synaptic transmission VDAC1;GLRB;CACNA1G;GLRA1;OPRM1;OPRD1;GLRA3;HTR2A GO:0010629| negative regulation of gene expression OPRD1 19798:[DB14011 DB00929] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGER4;PTGS2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;PTGER4 GO:0031622| positive regulation of fever generation CNR1;PTGS2;PTGER3 GO:0006955| immune response PTGER4;CNR2;OPRD1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;PTGER4;CHRNA7;PTGER2;GPR12;CNR1;HTR2A;GPR55;HTR1A;PTGER3;OPRD1;CNR2;OPRM1 GO:0050729| positive regulation of inflammatory response PTGER4;TRPV4 GO:0071380| cellular response to prostaglandin E stimulus PTGER4;PPARG;PTGER2 GO:0009612| response to mechanical stimulus TRPV4;PTGER4;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger PTGER3;OPRD1;OPRM1;HTR2A GO:0042127| regulation of cell proliferation PTGS1;PTGER2;PTGS2 GO:0032496| response to lipopolysaccharide PTGER2;CNR2;PTGS2;CYP1A2;OPRM1;CNR1;IDO1;PTGER4;CYP1A1 GO:0050728| negative regulation of inflammatory response PTGER4;CNR2 GO:0007186| G-protein coupled receptor signaling pathway PTGER2;OPRD1;PTGER3;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;PTGER4;GPR18;PPARG GO:0008219| cell death PTGER3;HTR2A 19799:[DB14011 DB01270] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01270|Ranibizumab VEGFA common genes common pathways GO:0030224| monocyte differentiation VEGFA;PPARG GO:0030324| lung development VEGFA;CYP1A2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;VEGFA;HMGCR;SOD1 GO:0001822| kidney development CAT;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;VEGFA;PTGS2;HMGCR GO:0002576| platelet degranulation SOD1;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;TRPV4;TRPV1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;VEGFA GO:0001541| ovarian follicle development VEGFA;SOD1 GO:0030855| epithelial cell differentiation VDAC1;PPARG;VEGFA GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;VEGFA;HMGCR GO:0010628| positive regulation of gene expression TRPV4;VEGFA GO:0001666| response to hypoxia CHRNA7;CAT;VEGFA;CYP1A1 GO:0043406| positive regulation of MAP kinase activity VEGFA;HTR2A GO:0071456| cellular response to hypoxia SLC29A1;VEGFA;PTGS2;OPRD1 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0010629| negative regulation of gene expression VEGFA;OPRD1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0001934| positive regulation of protein phosphorylation CHRNA7;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;VEGFA GO:0007595| lactation SLC29A1;VEGFA GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0048469| cell maturation VEGFA;PPARG GO:0001525| angiogenesis CYP1B1;PTGS2;VEGFA GO:0007399| nervous system development SMPD1;GLRB;VEGFA GO:0051781| positive regulation of cell division CAT;VEGFA GO:0043117| positive regulation of vascular permeability VEGFA;TRPV4 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2;OPRD1 19800:[DB14011 DB00799] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00799|Tazarotene RARA;RXRB;RARG;RARB;CYP2C8 common genes common pathways GO:0032526| response to retinoic acid RARA;RARG;PPARG GO:0034097| response to cytokine stimulus PTGS2;AANAT;RARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARA;RARG;TRPV1;TRPV4;RARB;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;RARG;RARB;PLA2G1B;RXRB;PPARG GO:0008284| positive regulation of cell proliferation RARB;RARA;RARG;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;RARA;GPX1;RARG;CAT;RARB GO:0071300| cellular response to retinoic acid RARA;RARG;PPARG GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP1A2 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2C8;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0006355| regulation of transcription, DNA-dependent RARG;RARA;RXRB;PPARG;RARB GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRB;RARB;RARA;RARG GO:0033189| response to vitamin A RARA;CAT;CYP1A1;PPARG GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;RARA;CAT GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP1A2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;RARA;CHRNA7 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5;CYP2C8 GO:0045892| negative regulation of transcription, DNA-dependent RARA;PPARG GO:0001657| ureteric bud development RARB;CAT;RARA GO:0007283| spermatogenesis SOD1;CNR1;RARA GO:0043277| apoptotic cell clearance RARA;ALOX15 GO:0010628| positive regulation of gene expression TRPV4;RARA;RARG GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;RARA;CAT GO:0006351| transcription, DNA-dependent RARB;RXRB;PPARG;RARA;RARG GO:0001889| liver development CYP1A1;ACAT1;RARA GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRB;RARB;RARA;RARG GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;RARG;SMPD1;PPARG;RARB;TRPV1;CYP1B1;IDO1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0007565| female pregnancy RARA;IDO1 GO:0042738| exogenous drug catabolic process CYP2C8;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;RARA GO:0022008| neurogenesis DAGLA;RARB GO:0007165| signal transduction RARA;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PLA2G1B;CACNA1I;RARB;SMPD1;PPARG;GPR18 GO:0097267| CYP1A2;CYP2C19;CYP2C8;CYP1B1;CYP2C9;CYP1A1 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0043010| camera-type eye development CYP1A1;RARG GO:0008285| negative regulation of cell proliferation RARB;CYP1B1;PPARG;RARA;RARG;PTGS2;OPRM1 19801:[DB14011 DB01581] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01581|Sulfamerazine ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0098869| ALB;GSR;PTGS2;CAT;GPX1;PTGS1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0002576| platelet degranulation ALB;SOD1 19802:[DB14011 DB07246] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways GO:0007566| embryo implantation SOD1;PTGS2;MMP9 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;MMP9 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;MMP9;CYP1B1;TRPV1;IDO1 GO:0001503| ossification ALOX15;MMP9 GO:0001934| positive regulation of protein phosphorylation MMP9;CHRNA7 GO:0043388| positive regulation of DNA binding MMP9;PPARG GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;MMP9 GO:0043312| neutrophil degranulation ALOX5;CAT;MMP9 19803:[DB14011 DB09033] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09033|Vedolizumab ITGA4;ITGB7 common genes common pathways GO:0007155| cell adhesion CYP1B1;ITGB7;ITGA4 GO:0046718| entry of virus into host cell HTR2A;ITGB7 GO:0071345| cellular response to cytokine stimulus TRPV1;ITGA4 19804:[DB14011 DB01000] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;SLC15A1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;TRPV3;CACNA1H;SLC15A2;SLC22A5;GLRA3;TRPV2;CHRNA7 GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCG2 GO:0006810| transport TRPV2;SLC15A2;CACNA1I;TRPV1;ABCG2;ABCC1;SLC15A1 GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC15A2;SLC22A5;TRPV2;CACNA1G;ABCC1;SLC15A1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8 19805:[DB14011 DB06154] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0035556| intracellular signal transduction PLA2G1B;GUCY1A2 GO:0008152| metabolic process ACAT1;ALDH2;SMPD1 GO:0042542| response to hydrogen peroxide HBB;TRPA1;HBA1;CAT;GPX1;SOD1 GO:0009408| response to heat NOS3;TRPV1;TRPV2;SOD1;TRPV3 GO:0010942| positive regulation of cell death HBB;HBA1;PTGS2 GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0007165| signal transduction SMPD1;PPARG;GUCY1A2;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0051291| protein heterooligomerization GLRB;GLRA1;HBB;HBA1 GO:0008285| negative regulation of cell proliferation NOS3;CYP1B1;PPARG;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;HBB;PPARG;NOS3 GO:1902042| GPX1;NOS3 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0030324| lung development CYP1A2;NOS3 GO:0042311| vasodilation GPX1;NOS3 GO:0043312| neutrophil degranulation CAT;ALOX5;HBB GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0022900| electron transport chain GSR;IDO1;ALDH2;CYP1A2 GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;NOS3;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;ALDH2;CYP3A7 GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;TRPV1;OPRM1;PTGS2 GO:0098869| PTGS2;GPX1;PTGS1;CAT;HBB;HBA1;GSR GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;HBA1;HBB GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;NOS3 19806:[DB14011 DB00847] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0019430| removal of superoxide radicals MPO;SOD1 GO:0009408| response to heat TRPV2;SST;SOD1;TRPV3;TRPV1 GO:0007268| synaptic transmission OPRM1;OPRD1;SST;HTR2A;GLRA3;CACNA1G;GLRA1;NPY2R;GLRB;VDAC1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;SST GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;SST GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;NPY2R GO:0001662| behavioral fear response VDAC1;NPY2R;HTR1A GO:0007584| response to nutrient PPARG;HMGCR;SST;CNR1 GO:0045987| positive regulation of smooth muscle contraction NPY2R;PTGS2 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;NPY2R GO:0065009| regulation of molecular function NPY2R;TRPV1 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;PLA2G1B;NPY2R;CACNA1I;SMPD1;GPR18;PPARG GO:0010811| positive regulation of cell-substrate adhesion NPY2R;ALOX15 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway NPY2R;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration NPY2R;TRPV4;TRPV1;OPRM1;HTR2A GO:0051967| negative regulation of synaptic transmission, glutamatergic NPY2R;HTR2A GO:0010243| response to organic nitrogen TRPV1;SST;PTGS2 GO:0055114| oxidation-reduction process CAT;GPX1;MPO;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0032094| response to food CYP1A1;MPO;OPRM1 GO:0042493| response to drug HTR2A;SOD1;SST;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0043312| neutrophil degranulation MPO;ALOX5;CAT GO:0009612| response to mechanical stimulus MPO;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process MPO;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0007218| neuropeptide signaling pathway GLRA1;NPY2R;GLRB;OPRD1;OPRM1;GLRA3 GO:0007626| locomotory behavior NPY2R;OPRM1;SOD1 GO:0032496| response to lipopolysaccharide MPO;PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0043200| response to amino acid stimulus GLRB;GLRA3;SST GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;MPO;PTGS1;CAT GO:0007568| aging NPY2R;CYP1A1;MPO;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;SST;GPR12;CNR1;HTR2A;NPY2R;PPARG;GPR18 19807:[DB14011 DB07029] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GSR;NOS2;GPX1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0032496| response to lipopolysaccharide CYP1A1;NOS2;IDO1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;NOS2;CRYZ;CYP1A1;CYP2C9 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0001666| response to hypoxia NOS2;CYP1A1;CHRNA7;CAT 19808:[DB14011 DB06939] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0001666| response to hypoxia CYP1A1;DPP4;CHRNA7;CAT 19809:[DB14011 DB06162] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06162|Lumiliximab FCER2 common genes common pathways 19810:[DB14011 DB04270] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes PPARG common pathways GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0030224| monocyte differentiation PPARG GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0032526| response to retinoic acid PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0030308| negative regulation of cell growth PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0055088| lipid homeostasis PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0048469| cell maturation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG 19811:[DB14011 DB08186] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08186|(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE KAT2B common genes common pathways GO:0032869| cellular response to insulin stimulus KAT2B;PLA2G1B;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2;KAT2B GO:0006351| transcription, DNA-dependent KAT2B;PPARG GO:0016032| viral reproduction VDAC1;KAT2B;HTR2A GO:0048511| rhythmic process PPARG;AANAT;KAT2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;KAT2B GO:0045893| positive regulation of transcription, DNA-dependent KAT2B;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;KAT2B GO:0006367| transcription initiation from RNA polymerase II promoter KAT2B;PPARG 19812:[DB14011 DB06097] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06097|GSK-923295 CENPE common genes common pathways 19813:[DB14011 DB09459] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;HIF1AN GO:0006355| regulation of transcription, DNA-dependent HIF1AN;PPARG GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;HIF1AN;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;PTGS1;ALOX5;GPX1 19814:[DB14011 DB08200] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08200|(1R)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCHE;PPARG;CYP1B1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;BCHE;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0007612| learning PTGS2;VDAC1;BCHE 19815:[DB14011 DB05787] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05787|LM-609 ITGB3 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;ITGB3 GO:0016032| viral reproduction HTR2A;ITGB3;VDAC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;HTR2A GO:0046718| entry of virus into host cell ITGB3;HTR2A GO:0060055| angiogenesis involved in wound healing GPX1;ITGB3 GO:0010745| negative regulation of macrophage derived foam cell differentiation ITGB3;PPARG GO:0042060| wound healing ITGB3;ALOX15;OPRM1 GO:0002576| platelet degranulation ITGB3;SOD1 GO:0007155| cell adhesion ITGB3;CYP1B1 GO:0043277| apoptotic cell clearance ITGB3;ALOX15 19816:[DB14011 DB08884] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ABCC4;AANAT;ACAT1;CYP1A2;PTGS2 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;SLCO1B3;SLCO1B1;GLRA3;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0006855| drug transmembrane transport ABCC1;ABCC3;ABCG2;ABCC2 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0042908| xenobiotic transport ABCC1;ABCC3;ABCG2 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0007565| female pregnancy IDO1;ABCC2 GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1;ABCC2 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLCO1B1;SLCO1B3;ABCC4;TRPV2;ABCC1;ABCC3;CACNA1G;TRPA1;CACNA1I;TRPV4;VDAC1;TRPV1;ABCC2;TRPM8;ABCG2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1;ABCC4 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0006810| transport ABCC3;ABCC1;TRPV1;CACNA1I;ABCG2;ABCC2;TRPV2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1;ABCC2 GO:0099133| ABCC2;ABCC1;ABCC3;ABCC4 GO:0042493| response to drug ABCC2;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCC4;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ABCC4;PTGS1;ALOX5;GPX1;CRYZ;CYP2C9;CYP1A1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;HMGCR;PTGS2 GO:0010243| response to organic nitrogen TRPV1;ABCC4;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;ABCC2;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0002576| platelet degranulation ABCC4;SOD1 19817:[DB14011 DB12712] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12712|Pilsicainide ABCB11 common genes common pathways GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;ABCB11 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;CACNA1G;ABCC1;TRPV2;ABCB11;CACNA1H;TRPV3 GO:0006810| transport TRPV2;ABCB11;TRPV1;CACNA1I;ABCG2;ABCC1 19818:[DB14011 DB12961] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways GO:0007218| neuropeptide signaling pathway OPRM1;LTB4R;OPRD1;GLRA3;GLRA1;GLRB;LTB4R2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PPARA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;TRPV4;TRPV1;PPARG GO:0042060| wound healing ALOX15;PPARA;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LTB4R2;OPRM1;LTB4R;OPRD1;HTR2A GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0050728| negative regulation of inflammatory response CNR2;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARG GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PPARA;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0006936| muscle contraction GLRA1;CACNA1H;LTB4R GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;LTB4R;CNR2;OPRD1;LTB4R2;PPARG;GPR18 GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0001666| response to hypoxia CYP1A1;PPARA;CAT;CHRNA7 GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PPARA;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0007507| heart development PPARA;PPARG GO:0007194| negative regulation of adenylate cyclase activity OPRM1;LTB4R2 GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0006955| immune response LTB4R;CNR2;OPRD1 GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;LTB4R;PTGS2;TRPV1;ALOX15;IDO1 GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;LTB4R;OPRM1;OPRD1;CACNA1I;LTB4R2;PLA2G1B;PPARG;GPR18;SMPD1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;PPARA;CNR1;HMGCR GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0032868| response to insulin stimulus CAT;AANAT;PPARA;TRPV4 19819:[DB14011 DB05458] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways GO:0007613| memory CHRNB2;PTGS2;CNR1;HTR2A;CHRNA7 GO:0007601| visual perception GLRB;CYP1B1;GLRA1;CRYZ;CHRNB2 GO:0050890| cognition CHRNA7;CHRNA4;CHRNB2 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNB2;CHRNA7;CHRNA4;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0006939| smooth muscle contraction HTR2A;CHRNB2 GO:0006811| ion transport CHRNA7;TRPV2;CHRNA4;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA1;TRPA1;CHRNB2;CACNA1G GO:0042053| regulation of dopamine metabolic process CHRNB2;HTR1A GO:0051291| protein heterooligomerization GLRB;GLRA1;CHRNB2 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;CHRNB2 GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;CHRNA4;CHRNB2;TRPA1;TRPV1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CHRNB2 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;CHRNA4;GLRA1;CACNA1G;VDAC1;GLRB GO:0008542| visual learning HMGCR;CHRNB2 GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;TRPV2;CHRNA4;TRPA1;CHRNB2;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I GO:0045759| negative regulation of action potential CHRNB2;CNR1;CNR2 GO:0007605| sensory perception of sound GPX1;SOD1;CHRNB2 GO:0042391| regulation of membrane potential CACNA1H;CHRNA4;CHRNB2;CACNA1G;GLRA1;GLRB GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;CHRNA4;SOD1;PTGS2 GO:0042220| response to cocaine CHRNB2;SMPD1;CNR1;OPRM1 GO:0095500| CHRNB2;CHRNA4;CHRNA7 GO:0034220| ion transmembrane transport CHRNB2;GLRA1;TRPA1;TRPV1;GLRB;GLRA3;CHRNA4;CHRNA7 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;CHRNA4 GO:0014059| regulation of dopamine secretion CHRNB2;HTR2A;CHRNA4 GO:0001666| response to hypoxia CHRNB2;CYP1A1;CHRNA4;CAT;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;CHRNB2;TRPV1;GLRB;GLRA3;OPRM1;CHRNA7;CHRNA4;SLC29A1 GO:1905144| CHRNA7;CHRNB2 GO:0001508| regulation of action potential GLRA1;CACNA1G;CHRNB2;CHRNA4 GO:0007612| learning PTGS2;CHRNB2;VDAC1 GO:0007626| locomotory behavior CHRNB2;OPRM1;SOD1;CHRNA4 GO:0035640| exploration behavior CHRNA4;HTR1A GO:0035094| response to nicotine CHRNB2;CNR1;CHRNA7;CHRNA4 19820:[DB14011 DB05190] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05190|XL281 BRAF;RAF1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;RAF1;HMGCR;PTGS2;BRAF GO:0042127| regulation of cell proliferation BRAF;PTGS2;PTGS1 GO:0042060| wound healing RAF1;OPRM1;ALOX15 GO:0048538| thymus development BRAF;RAF1;SOD1 GO:0015758| glucose transport BRAF;PLA2G1B GO:0001666| response to hypoxia CHRNA7;CAT;RAF1;CYP1A1 GO:0010628| positive regulation of gene expression BRAF;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;BRAF;ALOX15;CHRNA7;OPRM1;RAF1;HMGCR;GPR55;HTR2A GO:0006915| apoptotic process VDAC1;RAF1;GPX1 GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;CHRNA7;GLRA3;RAF1 GO:0051591| response to cAMP AANAT;BRAF GO:0007507| heart development RAF1;PPARG GO:1990090| TRPV1;BRAF GO:0035556| intracellular signal transduction RAF1;BRAF;PLA2G1B GO:0071277| cellular response to calcium ion ALOX15;BRAF GO:0008542| visual learning HMGCR;BRAF GO:0001934| positive regulation of protein phosphorylation RAF1;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;RAF1;PTGS2 GO:0043524| negative regulation of neuron apoptosis BRAF;SOD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;RAF1;BRAF GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;RAF1;OPRD1;PLA2G1B;BRAF;CACNA1I;PPARG;GPR18;SMPD1 GO:0043434| response to peptide hormone stimulus TRPV1;BRAF GO:1902042| GPX1;RAF1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2;RAF1 GO:0051291| protein heterooligomerization GLRA1;BRAF;GLRB GO:0008283| cell proliferation HTR1A;RAF1;GPX1;CYP1A1 19821:[DB14011 DB08609] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08609|(2R)-N-{4-[Ethyl(phenyl)sulfamoyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide PDK2 common genes common pathways GO:0042593| glucose homeostasis PDK2;CNR1;TRPV4;PPARG 19822:[DB14011 DB06778] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes SOD1 common pathways GO:0046688| response to copper ion AANAT;SOD1;MT-CO1 GO:0007283| spermatogenesis SOD1;CNR1 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0046716| muscle cell homeostasis SOD1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 GO:0051591| response to cAMP TYR;AANAT GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CHRNA7 GO:0001541| ovarian follicle development SOD1 GO:0098869| PTGS2;GPX1;PTGS1;CAT;ALB;GSR GO:0006979| response to oxidative stress MT-CO1;PTGS2;SOD1;PTGS1;GPX1;CAT GO:0048538| thymus development SOD1;TYR GO:0007605| sensory perception of sound GPX1;SOD1 GO:0043085| positive regulation of catalytic activity SOD1 GO:0009060| aerobic respiration MT-CO1;CAT GO:0042554| superoxide anion generation SOD1 GO:0007568| aging MT-CO1;CYP1A1;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT GO:0048514| blood vessel morphogenesis LOX;CYP1B1 GO:0006801| superoxide metabolic process SOD1 GO:0034465| response to carbon monoxide SOD1 GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0022900| electron transport chain MAOB;IDO1;GSR;CYP1A2 GO:0042493| response to drug CAT;PTGS2;LOX;CYP1A2;HTR2A;SOD1;ABCG2;MAOB;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;LOX;PTGS2;CYP1A2;MAOA;HMGCR;CAT;TYR;ALOX5;CP;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;MAOB;MT-CO1;PAH;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1 GO:0007569| cell aging SOD1 GO:1902177| SOD1 GO:0035722| interleukin-12-mediated signaling pathway SOD1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0002576| platelet degranulation ALB;SOD1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0007626| locomotory behavior SOD1;OPRM1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0042060| wound healing OPRM1;LOX;ALOX15 GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;CYP1A1;MAOB;IDO1 GO:0030199| collagen fibril organization CYP1B1;LOX GO:0030324| lung development LOX;CYP1A2 GO:0097332| SOD1 GO:0034599| cellular response to oxidative stress GSR;CAT;GPX1;SOD1 GO:0001890| placenta development SOD1;PPARG GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0006749| glutathione metabolic process GSR;SOD1;GPX1 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0032930| positive regulation of superoxide anion generation SOD1 GO:0009411| response to UV TYR;CAT GO:0046620| regulation of organ growth SOD1 GO:0010269| response to selenium ion GPX1;MAOB GO:0009636| response to toxin GPX1;CAT;MAOB;CYP1A1;CYP1B1 GO:0033280| response to vitamin D TYR;PTGS2 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;CP GO:0008283| cell proliferation CYP1A1;GPX1;TYR;HTR1A GO:0001895| retina homeostasis SOD1;ALB GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0001819| positive regulation of cytokine production SOD1 GO:0060047| heart contraction GPX1;SOD1 GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0009725| response to hormone stimulus ACAT1;LOX GO:0040014| regulation of multicellular organism growth SOD1 GO:0007566| embryo implantation PTGS2;SOD1 GO:0001975| response to amphetamine SOD1;CNR2 GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0002262| myeloid cell homeostasis SOD1 GO:0007601| visual perception TYR;CRYZ;GLRA1;CYP1B1;GLRB GO:0019226| transmission of nerve impulse SOD1 GO:0043087| regulation of GTPase activity SOD1 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1 GO:0006879| cellular iron ion homeostasis ABCG2;CP;SOD1 GO:0019430| removal of superoxide radicals SOD1 GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels SOD1 GO:0043524| negative regulation of neuron apoptosis SOD1 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0008152| metabolic process ACAT1;TYR;PAH;SMPD1 GO:0042136| neurotransmitter biosynthetic process PAH;DAGLA GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;TRPA1 GO:0007507| heart development LOX;PPARG GO:0008090| retrograde axon cargo transport SOD1 GO:0000303| response to superoxide SOD1 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0045471| response to ethanol MAOB;OPRM1;HMGCR;SOD1;CNR1;CAT 19823:[DB14011 DB01038] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways GO:0014854| response to inactivity CAT;DRD2 GO:0009636| response to toxin CYP1A1;CYP1B1;DRD2;GPX1;CAT GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0001662| behavioral fear response VDAC1;HTR1A;DRD1 GO:0008285| negative regulation of cell proliferation CYP1B1;DRD2;PPARG;OPRM1;PTGS2 GO:0042053| regulation of dopamine metabolic process DRD1;HTR1A GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0007613| memory DRD1;CHRNA7;CNR1;HTR2A;PTGS2 GO:0072593| reactive oxygen species metabolic process SOD1;DRD5 GO:0001975| response to amphetamine DRD1;DRD5;SOD1;CNR2;DRD2 GO:0007165| signal transduction PLA2G1B;DRD2;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;DRD1;DRD5;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0050482| arachidonic acid secretion DRD2;PLA2G1B GO:1900273| DRD2;CHRNA7 GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;GLRA3;HTR2A;OPRM1;OPRD1;DRD5 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0008542| visual learning HMGCR;DRD1;DRD2 GO:0001964| startle response GLRA1;DRD2;GLRB GO:0019226| transmission of nerve impulse DRD1;DRD5;SOD1 GO:0045776| negative regulation of blood pressure DRD2;DRD5;CNR1 GO:0045471| response to ethanol DRD2;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0048678| response to axon injury DRD2;SOD1 GO:0019228| regulation of action potential in neuron CACNA1H;DRD1;CACNA1G;CACNA1I GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0001659| temperature homeostasis TRPV1;DRD2;HTR2A;GPX1;DRD1 GO:0048148| behavioral response to cocaine DRD2;DRD1;HTR2A GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;DRD2;TRPV4;ALOX15 GO:0042220| response to cocaine DRD2;SMPD1;DRD5;DRD1;OPRM1;CNR1 GO:0009416| response to light stimulus DRD2;AANAT GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRM1;CNR2;OPRD1;CNR1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;DRD2;GPR55;DRD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0014059| regulation of dopamine secretion DRD2;HTR2A GO:0010628| positive regulation of gene expression DRD1;TRPV4 GO:0001666| response to hypoxia CHRNA7;CAT;DRD2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway DRD2;PPARG;GPR18;DRD1;DRD5;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;DRD2;HTR2A GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;DRD5;CHRNA7;DRD2;TRPV4;TRPM8 GO:0006936| muscle contraction GLRA1;CACNA1H;DRD1 GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;DRD1;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;DRD2;ABCG2 GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0043278| response to morphine OPRM1;CNR1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;DRD2;GLRB;GLRA1;CHRNA7;SLC29A1;GLRA3;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0042060| wound healing ALOX15;OPRM1;DRD5 GO:0007612| learning VDAC1;DRD5;DRD1;PTGS2 GO:0007628| adult walking behavior GLRB;DRD2;GLRA1;DRD1 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0007626| locomotory behavior DRD2;DRD1;SOD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;DRD2;PPARG GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0042311| vasodilation GPX1;DRD1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD1;DRD5;OPRM1 19824:[DB14011 DB09028] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes CHRNA7 common pathways GO:0006811| ion transport CACNA1G;CHRNB2;GLRA1;TRPA1;TRPV4;CHRNA3;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8;TRPV3;CACNA1H;GLRA3;CHRNA6;CHRNA4;TRPV2;CHRNA7 GO:0051291| protein heterooligomerization GLRA1;CHRNB2;GLRB GO:0042053| regulation of dopamine metabolic process CHRNB2;HTR1A GO:0007601| visual perception CYP1B1;GLRB;CHRNB2;CRYZ;GLRA1 GO:0007613| memory CHRNB2;PTGS2;CNR1;HTR2A;CHRNA7 GO:0097061| dendritic spine organization CHRNA7 GO:0050890| cognition CHRNA4;CHRNA7;CHRNB2 GO:0007165| signal transduction CHRNA4;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CHRNA6;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;CHRNA3;CHRNB2;SMPD1;PPARG;GPR18 GO:1904645| CHRNA7 GO:1900273| CHRNA7 GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0006939| smooth muscle contraction HTR2A;CHRNB2 GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;CHRNA4;OPRD1;OPRM1;HTR2A;GLRA3;CHRNA6 GO:0008542| visual learning HMGCR;CHRNB2 GO:0006816| calcium ion transport CHRNA4;TRPV2;CHRNA7;TRPV3;CACNA1H;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;CHRNB2;TRPA1 GO:1902430| CHRNA7 GO:0019233| sensory perception of pain TRPV1;CHRNB2;TRPA1;CHRNA4;OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1 GO:0045471| response to ethanol CHRNB2;CAT;HMGCR;OPRM1;SOD1;CNR1 GO:0060078| regulation of postsynaptic membrane potential CHRNB2;CHRNA7;CHRNA6 GO:0007399| nervous system development GLRB;CHRNA3;SMPD1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B GO:0042220| response to cocaine CHRNB2;SMPD1;OPRM1;CNR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:1905920| CHRNA7 GO:0034220| ion transmembrane transport CHRNA3;GLRB;TRPV1;CHRNB2;GLRA1;TRPA1;CHRNA4;CHRNA7;GLRA3;CHRNA6 GO:0095500| CHRNA7;CHRNA4;CHRNB2;CHRNA3 GO:0060080| regulation of inhibitory postsynaptic membrane potential CHRNA4;GLRA1 GO:0014059| regulation of dopamine secretion CHRNA4;CHRNA6;HTR2A;CHRNB2 GO:1902991| CHRNA7 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:0001666| response to hypoxia CHRNB2;CYP1A1;CHRNA4;CHRNA7;CAT GO:0140059| CHRNA7 GO:0006810| transport CHRNA6;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0045759| negative regulation of action potential CHRNB2;CNR1;CNR2 GO:0098815| CHRNA7 GO:0007605| sensory perception of sound SOD1;GPX1;CHRNB2 GO:0042391| regulation of membrane potential GLRB;CHRNA3;GLRA1;CHRNB2;CACNA1G;CHRNA4;CACNA1H GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPV4;TRPM8 GO:1901214| CHRNA7 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1;CHRNA4 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:0050808| synapse organization CHRNA7 GO:0035094| response to nicotine CHRNB2;CHRNA4;CHRNA7;CHRNA6;CNR1 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0035640| exploration behavior CHRNA4;HTR1A GO:0050893| sensory processing CHRNA7 GO:1905906| CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA4;SLC29A1;CHRNA7;OPRM1;CHRNA6;GLRA3;TRPV1;CHRNA3;GLRB;CHRNB2;GLRA1 GO:0007614| short-term memory CHRNA7 GO:1905144| CHRNB2;CHRNA3;CHRNA7 GO:0007611| learning or memory CNR1;CHRNA7 GO:0001508| regulation of action potential CHRNA4;CHRNB2;CACNA1G;GLRA1 GO:0007612| learning VDAC1;CHRNB2;PTGS2 GO:0007626| locomotory behavior SOD1;OPRM1;CHRNA4;CHRNB2;CHRNA3 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A 19825:[DB14011 DB08234] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;DHFR;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2 19826:[DB14011 DB05777] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0002576| platelet degranulation F5;SOD1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;F2;PPARG;GPR18 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0061844| PLA2G1B;F2 19827:[DB14011 DB00452] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00452|Framycetin rpsL;CXCR4 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;CXCR4;TRPV1;TRPV4 GO:0071345| cellular response to cytokine stimulus CXCR4;TRPV1 GO:0007165| signal transduction HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CXCR4;PLA2G1B;CACNA1I GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;ALOX15;IDO1;CXCR4 GO:0016032| viral reproduction CXCR4;VDAC1;HTR2A GO:0006915| apoptotic process GPX1;CXCR4;VDAC1 GO:0000187| activation of MAPK activity PLA2G1B;CXCR4;SOD1;CHRNA7 GO:0048714| positive regulation of oligodendrocyte differentiation CXCR4;PPARG GO:0001666| response to hypoxia CYP1A1;CXCR4;CHRNA7;CAT GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CXCR4;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0009615| response to virus CYP1A1;CXCR4 19828:[DB14011 DB04638] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04638|2,5-DI-(TERT-BUTYL)-1,4,BENZOHYDROQUINONE ATP2A1 common genes common pathways GO:0070509| calcium ion import TRPV4;CACNA1I;ATP2A1;CACNA1G;CACNA1H GO:0034220| ion transmembrane transport GLRA3;CHRNA7;TRPA1;GLRA1;ATP2A1;TRPV1;GLRB GO:0006816| calcium ion transport CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;TRPM8;ATP2A1;TRPV3;CACNA1H;TRPV2;CHRNA7 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;ATP2A1;TRPM8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0034976| response to endoplasmic reticulum stress ATP2A1;ALOX15 GO:0070588| calcium ion transmembrane transport CACNA1H;OPRM1;TRPV3;TRPV2;CHRNA7;CACNA1G;TRPA1;CACNA1I;TRPV4;TRPV1;TRPM8;ATP2A1 19829:[DB14011 DB03351] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03351|Sri-9439 DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1A1;CYP2C9;DHFR;CRYZ;ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 19830:[DB14011 DB13191] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways GO:0032259| methylation CYP1A2;GAMT GO:0006936| muscle contraction GAMT;CACNA1H;CKMT2;SLC6A8;GLRA1 GO:0006810| transport SLC6A8;TRPV2;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0007283| spermatogenesis GAMT;CNR1;SOD1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;SLC6A8;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0007420| brain development CKB;ACAT1 GO:0040014| regulation of multicellular organism growth SOD1;GAMT GO:0006811| ion transport TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;SLC6A8;GLRA3;CACNA1H;TRPV3 19831:[DB14011 DB09067] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;CRHR1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0007565| female pregnancy CRHR1;IDO1 GO:0006955| immune response CNR2;OPRD1;CRHR1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CRHR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;CRHR1;GPR55;HTR1A;GPR18;PPARG 19832:[DB14011 DB08605] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways GO:0051289| protein homotetramerization TRPM8;TRPV1;DECR1;CRYZ;TRPA1;CAT GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;DECR1;PPARG;CYP2C9;GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;DECR1;CRYZ;CYP1A1;CYP2C9;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;DECR1;ALOX15 GO:0006635| fatty acid beta-oxidation ACAT1;DECR1 19833:[DB14011 DB05934] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05934|CTCE-0214 CXCL12 common genes common pathways GO:0007155| cell adhesion CYP1B1;CXCL12 GO:0009612| response to mechanical stimulus TRPV4;PPARG;CXCL12 GO:0008284| positive regulation of cell proliferation CXCL12;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0009615| response to virus CYP1A1;CXCL12 GO:0060326| cell chemotaxis CXCL12;ABCC1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;HTR2A;GPR12;CXCL12;CHRNA7 GO:0031100| organ regeneration PPARG;CXCL12 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;CXCL12;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0001666| response to hypoxia CHRNA7;CAT;CXCL12;CYP1A1 GO:0009314| response to radiation PTGS2;CXCL12;OPRM1;CAT GO:0051924| regulation of calcium ion transport OPRD1;CXCL12 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;CXCL12;HTR2A GO:0006955| immune response CXCL12;CNR2;OPRD1 GO:0009408| response to heat TRPV2;TRPV3;CXCL12;SOD1;TRPV1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain CXCL12;HTR2A;TRPA1 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CXCL12;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0007420| brain development ACAT1;CXCL12 GO:0043434| response to peptide hormone stimulus TRPV1;CXCL12 GO:0090280| positive regulation of calcium ion import TRPV2;CXCL12;TRPV3 GO:0061844| PLA2G1B;CXCL12 GO:0008344| adult locomotory behavior OPRD1;CXCL12 19834:[DB14011 DB06186] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06186|Ipilimumab CTLA4 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CTLA4;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0006955| immune response CTLA4;CNR2;OPRD1 GO:0002376| immune system process IDO1;CTLA4 GO:0042130| negative regulation of T cell proliferation IDO1;CTLA4 19835:[DB14011 DB06408] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0008152| metabolic process SMPD1;ENPP1;NT5C2;ACAT1 GO:0006955| immune response OPRD1;CNR2;ENPP1 GO:0006195| purine nucleotide catabolic process NT5C2;GPX1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;ENPP1 GO:0043312| neutrophil degranulation CAT;ALOX5;IMPDH1 GO:0030308| negative regulation of cell growth PPARG;ENPP1 GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;IMPDH1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP1A2;NT5C2;CYP3A4 19836:[DB14011 DB03126] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03126|Mant-Adp MYH14 common genes common pathways GO:0007605| sensory perception of sound SOD1;GPX1;MYH14 GO:0019228| regulation of action potential in neuron CACNA1H;MYH14;CACNA1I;CACNA1G 19837:[DB14011 DB05260] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0001660| fever generation IL1B;TRPV1 GO:0046330| positive regulation of JNK cascade TRPV4;IL1B GO:0071639| positive regulation of monocyte chemotactic protein-1 production IL1B;TRPV4 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IL1B;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;TFRC GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IL1B;PPARG;TFR2 GO:0002576| platelet degranulation TF;SOD1 GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;RRM2 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;PPARG GO:0071407| cellular response to organic cyclic compound IL1B;CYP1B1;CYP1A1 GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;IL1B;TRPV1 GO:0045766| positive regulation of angiogenesis IL1B;CYP1B1;CHRNA7 GO:0006915| apoptotic process IL1B;VDAC1;GPX1 GO:0000187| activation of MAPK activity IL1B;PLA2G1B;CHRNA7;SOD1 GO:0034220| ion transmembrane transport GLRB;TRPV1;GLRA1;TRPA1;ATP6V1B2;CHRNA7;GLRA3 GO:0043407| negative regulation of MAP kinase activity SMPD1;IL1B;HMGCR GO:0010628| positive regulation of gene expression IL1B;TRPV4 GO:0031622| positive regulation of fever generation PTGS2;CNR1;IL1B GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;IL1B;CYP1B1 GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B GO:0001934| positive regulation of protein phosphorylation IL1B;CHRNA7 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;IL1B GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;TFRC;TF;TFR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;PPARG GO:0016032| viral reproduction VDAC1;TFRC;HTR2A GO:0006955| immune response IL1B;CNR2;OPRD1 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;TRPV1;ALOX15;IDO1;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;IL1B;CAT GO:0050796| regulation of insulin secretion CNR1;IL1B GO:0007566| embryo implantation IL1B;PTGS2;SOD1 GO:0046718| entry of virus into host cell HTR2A;TFRC GO:0034116| positive regulation of heterotypic cell-cell adhesion IL1B;ALOX15 GO:0007165| signal transduction HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;IL1B;PLA2G1B;CACNA1I GO:0001895| retina homeostasis TF;SOD1 GO:0015949| nucleobase-containing small molecule interconversion RRM2;GSR GO:0006811| ion transport ATP6V1B2;GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;GLRA3;CACNA1H;TF;TRPV3;CHRNA7;TRPV2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;IL1B;CYP1B1 GO:0051781| positive regulation of cell division CAT;IL1B 19838:[DB14011 DB04977] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes CYP3A4 common pathways GO:0006641| triglyceride metabolic process CAT;GPX1;CYP2E1 GO:0097267| CYP4A11;CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP4A11;CYP1A1;PPARG GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP2A6;CYP3A4;CYP2C9;CYP2C19 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0045471| response to ethanol OPRM1;HMGCR;CYP2E1;SOD1;CNR1;CAT GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0010193| response to ozone CYP2E1;CAT GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2E1;CYP3A4;CYP2A6 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP2A6;CYP2E1;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1 GO:0010243| response to organic nitrogen TRPV1;PTGS2;CYP2E1 GO:0019369| arachidonic acid metabolic process CYP4A11;FAAH;CYP1B1;DAGLA;CYP2D6;ALOX15 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1;CYP2A6 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP1A1;CYP2C9;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP4A11;CYP1A2;CYP2A6;SOD1;CYP3A4;CYP2E1 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2;CYP4A11 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5;CYP4A11 GO:0042493| response to drug HTR2A;SOD1;CYP2E1;CYP1A2;PTGS2;CAT;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP1A2;CYP4A11;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 19839:[DB14011 DB07987] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07987|[2-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YLCARBAMOYL)-1-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER MMP3 common genes common pathways 19840:[DB14011 DB05931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05931|Pegdinetanib KDR common genes common pathways GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;KDR;TRPV4 GO:0045766| positive regulation of angiogenesis CHRNA7;KDR;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;KDR GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;KDR GO:0001525| angiogenesis KDR;CYP1B1;PTGS2 GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0016032| viral reproduction HTR2A;VDAC1;KDR 19841:[DB14011 DB01520] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes CHRNA7 common pathways GO:0050808| synapse organization CHRNA7 GO:0042493| response to drug CAT;GRIN2A;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0035094| response to nicotine CHRNA7;CNR1 GO:0050893| sensory processing CHRNA7 GO:1905906| CHRNA7 GO:1905144| CHRNA7 GO:0007614| short-term memory CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2C;GLRA1;GRIN3A;TRPV1;GLRB;GRIN3B;OPRM1;GRIN2D;GLRA3;GRIN2B;SLC29A1;CHRNA7;GRIN2A GO:0007611| learning or memory GRIN2A;CHRNA7;GRIN2B;CNR1 GO:0007612| learning VDAC1;GRIN2A;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:1905920| CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0034220| ion transmembrane transport TRPV1;GLRB;GRIN3B;GLRA1;TRPA1;GRIN3A;CHRNA7;GLRA3 GO:0095500| CHRNA7 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:1902991| CHRNA7 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0140059| CHRNA7 GO:0006810| transport TRPV2;GRIN2A;GRIN2B;CACNA1I;TRPV1;ABCG2;ABCC1;GRIN2C GO:0009611| response to wounding GRIN2A;GPX1;CYP1A1;GRIN2C GO:0098815| CHRNA7 GO:1901214| CHRNA7 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPV4;TRPM8 GO:0042391| regulation of membrane potential GLRB;GRIN2C;CACNA1G;GLRA1;GRIN2A;CACNA1H GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902004| CHRNA7 GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;OPRM1;OPRD1;GRIN2B;GLRA3;HTR2A;GRIN2A GO:0008542| visual learning HMGCR;GRIN2A GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:0006816| calcium ion transport GRIN2A;CHRNA7;TRPV2;CACNA1H;TRPV3;TRPM8;TRPV4;CACNA1I;TRPV1;GRIN3A;TRPA1;CACNA1G GO:0001964| startle response GLRB;GLRA1;GRIN2A;GRIN2D GO:1902430| CHRNA7 GO:0030431| sleep GRIN2A;SLC29A1;HTR2A;CACNA1I GO:0019233| sensory perception of pain GRIN2A;CNR1;HTR2A;PTGS2;CNR2;OPRM1;OPRD1;TRPV1;TRPA1 GO:0045471| response to ethanol GRIN3A;OPRM1;HMGCR;GRIN2B;SOD1;CNR1;CAT;GRIN2A GO:0060078| regulation of postsynaptic membrane potential GRIN2A;CHRNA7 GO:0042428| serotonin metabolic process GRIN2A;HTR1A GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;GRIN2A;PTGS2;SOD1;CNR1 GO:0008344| adult locomotory behavior GRIN2D;OPRD1 GO:0051930| regulation of sensory perception of pain GRIN2A;OPRD1;OPRM1;GRIN2D GO:0006811| ion transport TRPV2;GRIN2A;CHRNA7;TRPV3;GRIN2D;CACNA1H;GLRA3;GRIN2B;VDAC1;GRIN3B;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;GRIN2C;GLRA1;TRPA1;GRIN3A GO:0022008| neurogenesis DAGLA;GRIN2A GO:0007613| memory CHRNA7;GRIN2A;PTGS2;CNR1;HTR2A GO:0097061| dendritic spine organization CHRNA7 GO:0001975| response to amphetamine GRIN2A;SOD1;CNR2 GO:0050890| cognition CHRNA7 GO:0065009| regulation of molecular function GRIN2A;GRIN2B;GRIN2D;TRPV1;GRIN2C GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:1900273| GRIN2A;CHRNA7 GO:1904645| CHRNA7 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;CACNA1H;OPRM1;TRPV3;TRPM8;GRIN3B;CACNA1I;TRPV4;TRPV1;GRIN3A;TRPA1;CACNA1G 19842:[DB14011 DB00724] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0045087| innate immune response PPARG;TLR7;TLR8 GO:0009615| response to virus TLR8;CYP1A1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP2C9;CYP1A1;CRYZ;PTGS1;ALOX5;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0002376| immune system process IDO1;TLR8;TLR7 GO:0036378| CYP3A4 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001774| microglial cell activation TLR7;TLR8;TRPV1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR7;TLR8 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;PTGS1;NAAA;GPX1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;TLR8 GO:0006954| inflammatory response TLR7;ALOX15;IDO1;TLR8;TRPV1;CNR2;PTGS2;PTGS1;ALOX5 GO:0006955| immune response OPRD1;CNR2;TLR7 GO:0050729| positive regulation of inflammatory response TRPV4;TLR7 GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;TLR7;GPR18;SMPD1;TLR8;PLA2G1B;CACNA1I GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 19843:[DB14011 DB06271] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways GO:0007584| response to nutrient PPARG;HMGCR;CNR1;SERPINC1 GO:0002438| acute inflammatory response to antigenic stimulus SERPINC1;OPRM1 GO:0007595| lactation SERPINC1;SLC29A1 19844:[DB14011 DB03467] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes ABCG2;CYP1B1;ABCC1 common pathways GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1 GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0046415| urate metabolic process ABCG2 GO:0042448| progesterone metabolic process AKR1C1;CYP17A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0006351| transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;AKR1C1;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0042572| retinol metabolic process CYP1B1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;SLCO2B1 GO:0009636| response to toxin CAT;GPX1;CYP1B1;CYP1A1 GO:0002930| CYP1B1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0030336| negative regulation of cell migration CYP1B1 GO:0001523| retinoid metabolic process AKR1C1;NAPEPLD GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0070301| cellular response to hydrogen peroxide CYP1B1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0046466| membrane lipid catabolic process CYP1B1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0015889| cobalamin transport ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1;TRPV1;TRPV4 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1 GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;ESR1;OPRD1;OPRM1;CNR2;ESR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;ABCB1 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0099133| ABCC1 GO:0022900| electron transport chain CYP1A2;CYP19A1;GSR;IDO1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP19A1;CYP2C9;CYP1A1;GPX1;ALOX5;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;AKR1C1;SOD1;CYP3A4 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 GO:0019369| arachidonic acid metabolic process CYP2D6;DAGLA;ALOX15;CYP1B1;FAAH GO:0006694| steroid biosynthetic process CYP19A1;CYP17A1;HMGCR GO:0061298| retina vasculature development in camera-type eye CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2;ESR1 GO:0008210| estrogen metabolic process CYP1B1 GO:0015886| heme transport ABCG2 GO:0060326| cell chemotaxis ABCC1 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0033344| cholesterol efflux ABCG2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0030199| collagen fibril organization CYP1B1 GO:0043542| endothelial cell migration CYP1B1 GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;ESR2;PLA2G1B;ESR1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;TRPV1;TRPV4;PPARG;ESR1 GO:0007155| cell adhesion CYP1B1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0055085| transmembrane transport SLCO2B1;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;ABCB1;TRPV4;TRPA1;ABCC1;CACNA1G;TRPV2;TRPV3;CACNA1H GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0030855| epithelial cell differentiation AKR1C1;PPARG;VDAC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0032355| response to estradiol stimulus CAT;ESR1;CYP1A2;PTGS2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9 GO:0048514| blood vessel morphogenesis CYP1B1 GO:0006810| transport TRPV2;ABCG2;TRPV1;CACNA1I;ABCB1;ABCC1 GO:0051260| protein homooligomerization ACAT1;GLRA3;AKR1C1;GLRA1 GO:0042574| retinal metabolic process AKR1C1;CYP1B1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;ESR1 19845:[DB14011 DB02230] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02230|Immucillin-G PNP common genes common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0006955| immune response CNR2;OPRD1;PNP GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0043312| neutrophil degranulation ALOX5;CAT;PNP GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PNP;PPARG;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 19846:[DB14011 DB00364] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent FGF2;EGF;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGF2;EGF GO:0042060| wound healing FGF2;OPRM1;ALOX15 GO:0045087| innate immune response FGB;FGA;PPARG GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation EGF;HTR1A;HTR2A;FGF2;PTGS2;HMGCR;CHRNA7 GO:0002576| platelet degranulation EGF;SOD1;FGB;FGG;FGA;ALB GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;FGF2 GO:0000187| activation of MAPK activity FGF2;EGF;SOD1;CHRNA7;PLA2G1B GO:0050714| positive regulation of protein secretion FGG;FGA;PLA2G1B;FGB GO:0070374| positive regulation of ERK1 and ERK2 cascade FGF2;OPRM1;HMGCR;GPR55;HTR2A;FGB;CHRNA7;FGG;TRPV4;FGA;ALOX15 GO:0043406| positive regulation of MAP kinase activity FGF2;HTR2A;EGF GO:0010628| positive regulation of gene expression TRPV4;EGF GO:0051209| release of sequestered calcium ion into cytosol TRPV1;TRPA1;HTR2A;FGF2 GO:0043388| positive regulation of DNA binding EGF;PPARG GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:0002376| immune system process FGB;IDO1;FGA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation EGF;HTR2A GO:0051592| response to calcium ion FGG;FGA;FGB;AANAT GO:0001525| angiogenesis CYP1B1;EGF;PTGS2;FGF2 GO:0061045| negative regulation of wound healing FGF2;HMGCR GO:0007399| nervous system development GLRB;SMPD1;FGF2 GO:0001895| retina homeostasis SOD1;ALB GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;FGF2 GO:1902042| GPX1;FGB;FGG;FGA GO:0051781| positive regulation of cell division CAT;FGF2 GO:0034116| positive regulation of heterotypic cell-cell adhesion FGB;FGG;ALOX15;FGA GO:0007165| signal transduction PPARG;GPR18;SMPD1;FGG;PLA2G1B;CACNA1I;FGA;HTR1A;GPR55;EGF;HTR2A;CNR1;GPR12;OPRM1;CNR2;FGF2;OPRD1;CHRNA7;FGB GO:0045907| positive regulation of vasoconstriction FGB;HTR2A;PTGS2;FGA;FGG 19847:[DB14011 DB02911] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02911|2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine NOS3 common genes common pathways GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP2C9;CYP1A1;NOS3;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1 GO:0030324| lung development CYP1A2;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0042311| vasodilation NOS3;GPX1 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0006809| nitric oxide biosynthetic process NOS3;CYP1B1 GO:1902042| GPX1;NOS3 GO:0008217| regulation of blood pressure PPARG;NOS3;SOD1;PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;NOS3;PPARG GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0009408| response to heat TRPV2;SOD1;TRPV3;NOS3;TRPV1 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0001525| angiogenesis PTGS2;CYP1B1;NOS3 19848:[DB14011 DB07579] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07579|BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE APCS common genes common pathways GO:0002674| negative regulation of acute inflammatory response APCS;PPARG GO:0045087| innate immune response PPARG;APCS GO:0061045| negative regulation of wound healing APCS;HMGCR 19849:[DB14011 DB07756] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways GO:0007517| muscle organ development CACNA1H;ACHE GO:0007155| cell adhesion CYP1B1;ACHE GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0008283| cell proliferation GPX1;HTR1A;ACHE;CYP1A1 19850:[DB14011 DB08612] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 19851:[DB14011 DB08347] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08347|4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile ADRB1 common genes common pathways GO:0002024| diet induced thermogenesis TRPV4;ADRB1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0001659| temperature homeostasis TRPV1;ADRB1;GPX1;HTR2A GO:0009409| response to cold PPARG;TRPA1;TRPM8;ADRB1 GO:0050873| brown fat cell differentiation ADRB1;PTGS2 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;ADRB1;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CHRNA7 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 19852:[DB14011 DB07142] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CRYZ;DHFR;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT 19853:[DB14011 DB08360] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08360|2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG GO:0006915| apoptotic process CSNK2A1;GPX1;VDAC1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;CSNK2A1;HMGCR;PTGS2 GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;CSNK2A1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006351| transcription, DNA-dependent CSNK2A1;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CSNK2A1;PTGS2 19854:[DB14011 DB02888] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02888|FKB-001 FKBP1A common genes common pathways GO:0006936| muscle contraction GLRA1;FKBP1A;CACNA1H GO:0051209| release of sequestered calcium ion into cytosol FKBP1A;TRPV1;TRPA1;HTR2A GO:0031000| response to caffeine PPARG;FKBP1A GO:1902991| CHRNA7;FKBP1A GO:0070588| calcium ion transmembrane transport TRPV4;CACNA1I;TRPV1;FKBP1A;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3 19855:[DB14011 DB03766] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways GO:0071356| cellular response to tumor necrosis factor TRPV1;FABP4 GO:0045892| negative regulation of transcription, DNA-dependent FABP4;PPARG GO:0097112| gamma-aminobutyric acid receptor clustering GPHN;GLRB GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;GPHN;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19 GO:0050729| positive regulation of inflammatory response FABP4;TRPV4 GO:0050872| white fat cell differentiation FABP4;PPARG GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0008152| metabolic process ACAT1;GPHN;SMPD1 19856:[DB14011 DB03552] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03552|3-Tyrosine TH common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;TH;ACAT1;AANAT GO:0042755| eating behavior OPRM1;OPRD1;TH GO:0014823| response to activity CAT;TH GO:0010043| response to zinc ion TH;AANAT GO:0007601| visual perception TH;GLRA1;CRYZ;GLRB;CYP1B1 GO:0033076| isoquinoline alkaloid metabolic process TH;CYP2D6 GO:0007613| memory CHRNA7;CNR1;TH;HTR2A;PTGS2 GO:0001975| response to amphetamine CNR2;TH;SOD1 GO:0043434| response to peptide hormone stimulus TH;TRPV1 GO:0050890| cognition CHRNA7;TH GO:0051412| response to corticosterone stimulus AANAT;TH GO:0031667| response to nutrient levels TH;SOD1 GO:0009635| response to herbicide CYP1A1;TH GO:0045471| response to ethanol CAT;SOD1;TH;CNR1;OPRM1;HMGCR GO:0008016| regulation of heart contraction TH;CACNA1H GO:0007507| heart development TH;PPARG GO:0042136| neurotransmitter biosynthetic process DAGLA;TH GO:0071312| cellular response to alkaloid TH;TRPV1 GO:0009416| response to light stimulus AANAT;TH GO:0001666| response to hypoxia TH;CAT;CHRNA7;CYP1A1 GO:0032355| response to estradiol stimulus TH;PTGS2;CYP1A2;CAT GO:0071363| cellular response to growth factor stimulus OPRD1;TH;CAT;TRPV1 GO:0007605| sensory perception of sound GPX1;SOD1;TH GO:0035900| response to isolation stress NAPEPLD;TH GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;TH;CYP3A4;ALOX5;PTGS1;GPX1;CAT GO:0006631| fatty acid metabolic process PTGS2;TH;PTGS1;ALOX15 GO:0042493| response to drug CYP1A2;PTGS2;TH;SOD1;HTR2A;CAT;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2 GO:0035094| response to nicotine CHRNA7;TH;CNR1 GO:0071333| cellular response to glucose stimulus TH;SLC29A1 GO:0007612| learning PTGS2;TH;VDAC1 GO:0032496| response to lipopolysaccharide CNR1;TH;OPRM1;CYP1A2;PTGS2;CNR2;CYP1A1;IDO1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2;TH GO:0070848| response to growth factor stimulus OPRM1;TH GO:0007626| locomotory behavior OPRM1;SOD1;TH 19857:[DB14011 DB02464] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;PRSS2 GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19858:[DB14011 DB03585] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03585|Oxyphenbutazone PLA2G2E;ALB;SLC22A6 common genes common pathways GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0036152| PLA2G1B;PLA2G2E GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0098869| ALB;GSR;PTGS2;PTGS1;GPX1;CAT GO:0055085| transmembrane transport ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;SLC22A6;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0016042| lipid catabolic process NAPEPLD;PLA2G2E;PLA2G1B;DAGLA GO:0006644| phospholipid metabolic process PLA2G2E;PLA2G1B;NAPEPLD GO:0036151| PLA2G2E;PLA2G1B GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;ALB GO:0006654| phosphatidic acid biosynthetic process PLA2G2E;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2E GO:0001895| retina homeostasis SOD1;ALB GO:0036150| PLA2G1B;PLA2G2E GO:0098656| SLC22A6;VDAC1 GO:0036149| PLA2G1B;PLA2G2E GO:0036148| PLA2G1B;PLA2G2E GO:0006629| lipid metabolic process PLA2G1B;TRPV1;PLA2G2E;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG;NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;PLA2G2E;ALOX15;IDO1 19859:[DB14011 DB03373] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03373|ZK-806711 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19860:[DB14011 DB08208] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways GO:0007165| signal transduction CHRNA7;MAP2K1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;PTGS2;CYP1B1;PPARG GO:0007507| heart development PPARG;MAP2K1 GO:0010629| negative regulation of gene expression OPRD1;MAP2K1 GO:0048538| thymus development MAP2K1;SOD1 GO:0000187| activation of MAPK activity PLA2G1B;MAP2K1;CHRNA7;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;MAP2K1;CHRNA7;TRPV4;ALOX15 GO:0010628| positive regulation of gene expression MAP2K1;TRPV4 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;PPARG 19861:[DB14011 DB02468] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;PTGS1;ALOX5;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;HMOX1;CYP3A4;SOD1 GO:0035094| response to nicotine CHRNA7;HMOX1;CNR1 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2;HMGCR GO:0006915| apoptotic process VDAC1;HMOX1;GPX1 GO:0008219| cell death HTR2A;HMOX1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;HMOX1 GO:0001666| response to hypoxia HMOX1;CHRNA7;CAT;CYP1A1 GO:0071456| cellular response to hypoxia HMOX1;PTGS2;OPRD1;SLC29A1 GO:0034605| cellular response to heat PTGS2;HMOX1;TRPV4;TRPV1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;HMOX1;SOD1;PTGS2 GO:0051260| protein homooligomerization GLRA1;ACAT1;HMOX1;GLRA3 GO:0043524| negative regulation of neuron apoptosis SOD1;HMOX1 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;HMOX1 GO:1904706| PPARG;HMOX1 GO:0001525| angiogenesis CYP1B1;PTGS2;HMOX1 GO:0035556| intracellular signal transduction PLA2G1B;HMOX1 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;HMOX1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;CAT;HMOX1;SOD1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;HMOX1 GO:0008217| regulation of blood pressure PTGS1;SOD1;HMOX1;PTGS2;PPARG GO:0043627| response to estrogen stimulus PPARG;HMOX1 GO:1902042| HMOX1;GPX1 GO:0071276| cellular response to cadmium ion HMOX1;SOD1;CYP1A2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;HMOX1 19862:[DB14011 DB08000] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08000|2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;AKR1B1 GO:0055114| oxidation-reduction process CRYZ;AKR1B1;CYP1A1;CYP2C9;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;PTGS1;GPX1 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0022900| electron transport chain GSR;IDO1;AKR1B1;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;AKR1B1;CYP1A1;PPARG;TRPA1 19863:[DB14011 DB00171] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes ABCC1 common pathways GO:0016032| viral reproduction VDAC1;SLC25A4;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity AKT1;PPARG GO:0060013| righting reflex AFG3L2;GLRA1;GLRB GO:0010976| positive regulation of neuron projection development ABL2;CNR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;ALK;PLA2G1B GO:0009408| response to heat ABCC2;TRPV1;SOD1;AKT1;TRPV3;TRPV2 GO:0006954| inflammatory response AKT1;CNR2;PTGS2;PIK3CA;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0009268| response to pH TRPV1;ABCC8 GO:0008542| visual learning HMGCR;ABCC8 GO:0042752| regulation of circadian rhythm ADCY1;PRKAA1;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;TNK2;HTR2A GO:1902476| GLRA3;GLRB;CFTR;GLRA1 GO:0002790| peptide secretion ABCA1;TRPV1 GO:0045859| regulation of protein kinase activity CSNK2B;SOD1 GO:0031667| response to nutrient levels ASNS;SOD1 GO:0010629| negative regulation of gene expression AKT1;OPRD1;ACVRL1;ACVR1B GO:0043524| negative regulation of neuron apoptosis SOD1;PIK3CA GO:0071320| cellular response to cAMP CFTR;AANAT GO:0006195| purine nucleotide catabolic process GPX1;NT5C2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process AKT1;CSNK2A1;PTGS2;GPX1 GO:0007565| female pregnancy ABCC8;IDO1;ABCC2 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7;AKT1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0008152| metabolic process NT5C2;ACAT1;ACSS1;ACSS2;SMPD1;ACSL1 GO:0035556| intracellular signal transduction ARAF;PLA2G1B;ADCY1;AKT1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;ABL1;APAF1;AKT1;PTGS2;SOD1;CNR1 GO:0016126| sterol biosynthetic process PRKAA1;HMGCR GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;PRKAA1;TRPA1 GO:0071361| cellular response to ethanol PRKAA1;GLRA1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;ABCA1;ALOX15;ACSL1;DAGLA;CYP2D6;PRKAA1;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0071260| cellular response to mechanical stimulus AKT1;PTGS2 GO:1990090| AKT1;TRPV1 GO:0007507| heart development ACVR1;PPARG GO:0007399| nervous system development APAF1;GLRB;SMPD1;AKT1;ALK GO:0061045| negative regulation of wound healing ABCC8;HMGCR GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;ABCB11;CACNA1H GO:0006351| transcription, DNA-dependent CSNK2A1;PPP5C;PPARG;PRKAA1 GO:0001889| liver development ACAT1;PIK3CA;ASNS;CYP1A1 GO:0000060| protein import into nucleus, translocation OPRD1;AKT1 GO:0045821| positive regulation of glycolysis PRKAA1;HTR2A GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;TNK2 GO:0001525| angiogenesis CYP1B1;PTGS2;ACVRL1;PIK3CA GO:0071277| cellular response to calcium ion ADCY1;ALOX15 GO:0060612| adipose tissue development ACAT1;PIK3CA GO:0019395| fatty acid oxidation PPARG;PRKAA1 GO:0010043| response to zinc ion AANAT;ABCC8 GO:0051291| protein heterooligomerization GLRA1;GLRB;PRKAA1;ACVRL1;PPP5C GO:0042178| xenobiotic catabolic process CRYZ;ACSL1 GO:0050896| response to stimulus TRPM8;TRPA1;ABCC6 GO:0009791| post-embryonic development CYP1A2;ABL1 GO:0030336| negative regulation of cell migration ACVRL1;CYP1B1 GO:0071276| cellular response to cadmium ion AKT1;CYP1A2;SOD1;PPP5C GO:0045600| positive regulation of fat cell differentiation PPARG;AKT1;HTR2A GO:0010887| negative regulation of cholesterol storage ABCG1;PPARG;ABCA1 GO:0071380| cellular response to prostaglandin E stimulus PRKAA1;PPARG;AKT1 GO:0043537| negative regulation of blood vessel endothelial cell migration ACVRL1;CSNK2B;PPARG GO:0098656| VDAC1;ABCA1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;ACVRL1;PPARG;CSNK2B;CYP1B1 GO:0008217| regulation of blood pressure SOD1;ACVRL1;PTGS2;PTGS1;PPARG GO:0014823| response to activity CAT;PRKAA1 GO:0006851| mitochondrial calcium ion transport VDAC1;AFG3L2 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0070301| cellular response to hydrogen peroxide PPP5C;ABL1;CYP1B1;PRKAA1 GO:0007584| response to nutrient HMGCR;ABCA1;CNR1;PPARG;APAF1;ACSL1 GO:0006919| activation of caspase activity PPARG;APAF1 GO:0009411| response to UV CAT;PRKAA1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;ASNS GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACSL1;CYP1A2;PTGS2;AANAT;ACAT1;ABCC4 GO:0010745| negative regulation of macrophage derived foam cell differentiation ABCG1;PPARG;ABCA1 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CFTR;CACNA1G;TRPA1;GLRA1 GO:0008283| cell proliferation GPX1;HTR1A;ALK;AKT1;CYP1A1 GO:0006809| nitric oxide biosynthetic process AKT1;CYP1B1 GO:0032868| response to insulin stimulus AANAT;CAT;ABCC8;TRPV4 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2;ABCG2 GO:0007548| sex differentiation CYP17A1;AMHR2 GO:0048643| positive regulation of skeletal muscle tissue development PRKAA1;HMGCR GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H;ASNS GO:0006821| chloride transport GLRB;CFTR;GLRA1;GLRA3 GO:0045907| positive regulation of vasoconstriction HTR2A;AKT1;PTGS2 GO:0014065| phosphatidylinositol 3-kinase cascade AKT1;HTR2A;PIK3CA GO:0006641| triglyceride metabolic process ACSL1;CAT;GPX1 GO:0010332| response to gamma radiation PRKAA1;GPX1 GO:0065009| regulation of molecular function ABCC9;TRPV1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PRKAA1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PIK3CA;AKT1;OPRD1;PTGS2;ARAF GO:0007165| signal transduction ARAF;CSNK2B;ADCY1;PRKAA1;PLA2G1B;CACNA1I;ABCC9;GPR18;NAE1;PPARG;SMPD1;CHRNA7;ABCC8;HTR2A;CNR1;GPR12;ACVR1B;ABL2;GPR55;HTR1A;ACVRL1;P2RY11;ALK;OPRD1;AKT1;CSNK2A1;AMHR2;TNK2;OPRM1;CNR2 GO:0007420| brain development APAF1;ALK;ACAT1 GO:0009725| response to hormone stimulus ACAT1;AKT1 GO:0045332| phospholipid translocation ABCA1;ABCC1;ABCB1 GO:0010226| response to lithium ion ADCY1;PTGS2 GO:0099039| ABCC1 GO:0090201| negative regulation of release of cytochrome c from mitochondria AKT1;GPX1 GO:0019216| regulation of lipid metabolic process ACSL1;PPARG;CYP1A1;CNR1;ABCA1;HMGCR GO:0040014| regulation of multicellular organism growth SOD1;PIK3CA;AFG3L2 GO:0032287| peripheral nervous system myelin maintenance AKT1;SOD1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0031999| negative regulation of fatty acid beta-oxidation CNR1;AKT1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADCY1;OPRM1;OPRD1 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1;ABCC6 GO:0001649| osteoblast differentiation CAT;AKT1 GO:0007613| memory ABCC8;CNR1;HTR2A;PTGS2;CHRNA7 GO:0032869| cellular response to insulin stimulus AKT1;PLA2G1B;PPARG GO:0050796| regulation of insulin secretion SLC25A4;ABCC8;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ABL1;OPRM1;ABL2;HTR2A GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKT1;HMGCR;ABCC4 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;ABCA1 GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;PRKAA1 GO:0010243| response to organic nitrogen TRPV1;ABCC4;PTGS2 GO:0016525| negative regulation of angiogenesis PPARG;ABCC8 GO:0043278| response to morphine OPRM1;PPP5C;CNR1 GO:0060326| cell chemotaxis ABCC1;PIK3CA GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PIK3CA GO:0061298| retina vasculature development in camera-type eye CYP1B1;ACVRL1 GO:0032094| response to food AKT1;OPRM1;CYP1A1 GO:0071407| cellular response to organic cyclic compound AKT1;CYP1B1;CYP1A1 GO:0099133| ABCC8;ABCC4;CFTR;ABCC1;ABCC6;ABCC9;ABCC2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15;ACSL1;PRKAA1 GO:0045893| positive regulation of transcription, DNA-dependent ACVR1;AKT1;ACVRL1;PPARG GO:0042493| response to drug SOD1;HTR2A;ABCC8;ABCA1;PTGS2;CYP1A2;CAT;ABCC4;TRPA1;ABCC9;CYP1A1;PPARG;ABCC1;SMPD1;ABCC6;ACSL1;ABCC2;ABCG2;ADCY1;ABCB1 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ABCG1;ABL1;PRKAA1;ACVRL1;ACVR1B;CSNK2A1 GO:0016236| macroautophagy PRKAA1;VDAC1;CSNK2B;CSNK2A1 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;ABCC4;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:1902176| AKT1;GPX1 GO:0071300| cellular response to retinoic acid PPARG;ABCA1;ABL2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;AKT1;HMGCR;SOD1;ASNS;PRKAA1;ARAF GO:0009612| response to mechanical stimulus PPARG;TRPV4;ASNS GO:0002576| platelet degranulation SOD1;ABCC4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ACVR1;AKT1;ACVRL1;ACVR1B;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation PRKAA1;PTGS2;AKT1;HMGCR;CSNK2A1;HTR1A;HTR2A;CHRNA7 GO:0010288| response to lead ion CAT;PPP5C GO:0043312| neutrophil degranulation CSNK2B;APAF1;ALOX5;CAT GO:0045087| innate immune response PPARG;ABL1;ABL2;TNK2;PIK3CA GO:0007155| cell adhesion CYP1B1;ABL1;ABL2 GO:0043523| regulation of neuron apoptosis GPX1;NAE1 GO:0030308| negative regulation of cell growth PPARG;ACVR1B;ACVRL1 GO:0071318| cellular response to ATP TRPV1;P2RY11;PTGS2;SOD1 GO:0042127| regulation of cell proliferation ABL1;ABL2;TNK2;PTGS2;ALK;PTGS1 GO:0007623| circadian rhythm AANAT;ASS1;ADCY1 GO:0008203| cholesterol metabolic process ABCG1;PRKAA1;ABCA1;HMGCR;CAT GO:0032496| response to lipopolysaccharide ABCC8;CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;IDO1;ABCC2 GO:0043542| endothelial cell migration ABL1;CYP1B1;PIK3CA GO:0006695| cholesterol biosynthetic process HMGCR;PRKAA1;CFTR GO:0071333| cellular response to glucose stimulus SLC29A1;PIK3CA GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;P2RY11 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;AKT1;OPRM1;CHRNA7;SLC29A1;GLRA1;GLRB;TRPV1 GO:0034599| cellular response to oxidative stress ABL1;GSR;CAT;GPX1;SOD1 GO:0033344| cholesterol efflux ABCG1;ABCG2;ABCA1 GO:0010628| positive regulation of gene expression ACVR1B;TRPV4;PRKAA1 GO:0001666| response to hypoxia PRKAA1;APAF1;CYP1A1;CAT;CHRNA7;ACVRL1 GO:0006085| acetyl-CoA biosynthetic process ACSS2;ACSS1;ACAT1 GO:0010033| response to organic substance ABCC4;SOD1;AKT1;PTGS2;CYP1A2;ACSL1;TRPA1;CYP1A1;PPARG;ABCG1 GO:0031000| response to caffeine PRKAA1;PPARG GO:0015758| glucose transport AKT1;PLA2G1B GO:0050891| multicellular organismal water homeostasis CFTR;TRPV4 GO:0071356| cellular response to tumor necrosis factor AKT1;TRPV1;ABCC2 GO:0009416| response to light stimulus AANAT;ASNS GO:0048511| rhythmic process PRKAA1;ADCY1;PPARG;AANAT;CSNK2A1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ASNS GO:0000187| activation of MAPK activity ALK;SOD1;CHRNA7;PLA2G1B;PRKAA1 GO:0006915| apoptotic process GPX1;CSNK2A1;AKT1;VDAC1;ABL1;APAF1;NAE1 GO:0045766| positive regulation of angiogenesis CHRNA7;ACVRL1;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ARAF;ABL1;ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0055085| transmembrane transport ABCG2;ABCC2;TRPM8;TRPV1;VDAC1;ABCB1;CACNA1I;TRPV4;ABCC9;TRPA1;CACNA1G;CFTR;ABCC6;SLC25A4;ABCG1;ABCC1;TRPV2;ABCC4;ABCC8;ABCB11;CACNA1H;ABCA1;TRPV3 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;AKT1;ASS1;OPRM1;PTGS2 GO:0006979| response to oxidative stress PTGS2;AKT1;SOD1;GPX1;PTGS1;CAT;ABL1;ABCC2 GO:0033993| response to lipid ABCG1;PPARG GO:0042593| glucose homeostasis AKT1;CNR1;PRKAA1;TRPV4;PPARG GO:0051260| protein homooligomerization ACAT1;GLRA3;APAF1;GLRA1 GO:0048538| thymus development ABL1;SOD1 GO:0036269| IDO1;ALK GO:0017144| drug metabolic process CYP1A2;CYP3A4;NT5C2;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP17A1;PRKAA1;CYP1B1;CYP3A4;HMGCR;ABCA1;CYP3A7;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;HTR1A;GPR55;AKT1;OPRD1;P2RY11;ABCA1;OPRM1;CNR2;PIK3CA;GPR18;PPARG;ADCY1 GO:0009235| cobalamin metabolic process ABCC1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;AKT1;TRPV1 GO:0007568| aging CAT;HMGCR;AKT1;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;APAF1;CYP1A1 GO:0048514| blood vessel morphogenesis ACVRL1;CYP1B1 GO:0006810| transport ABCB11;TRPV2;ASNA1;ABCC1;SLC25A4;ABCC6;ABCB1;CACNA1I;TRPV1;ABCC2;ABCG2 GO:0010468| regulation of gene expression PIK3CA;CYP1A2 GO:0071456| cellular response to hypoxia PRKAA1;SLC29A1;PTGS2;OPRD1;AKT1 19864:[DB14011 DB08184] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08184|2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 19865:[DB14011 DB05766] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0051209| release of sequestered calcium ion into cytosol DRD2;TRPV1;TRPA1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;CHRM1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;DRD2;DRD3;GPR18;PPARG GO:0006874| cellular calcium ion homeostasis DRD3;TRPM8;DRD2;TRPV4;GPR12;HTR2A;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;DRD2;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0042220| response to cocaine CNR1;OPRM1;DRD3;SMPD1;DRD2 GO:0009416| response to light stimulus AANAT;DRD2 GO:0014059| regulation of dopamine secretion DRD2;DRD3;HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;DRD2;GPR55 GO:0001666| response to hypoxia CAT;CHRNA7;DRD2;CYP1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;DRD2;GLRB;TRPV1;GLRA1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0007612| learning DRD3;VDAC1;PTGS2 GO:0007611| learning or memory CNR1;CHRNA7;DRD3 GO:0007628| adult walking behavior DRD2;GLRB;GLRA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DRD3;PPARG;TRPV1;TRPV4 GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0007626| locomotory behavior DRD3;DRD2;SOD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;PPARG;PLA2G1B;DRD2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;CHRM1;HTR2A;DRD3 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD3 GO:0042493| response to drug ABCG2;DRD2;CYP1A1;PPARG;TRPA1;DRD3;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0043278| response to morphine DRD2;DRD3;CNR1;OPRM1 GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0050890| cognition CHRM1;CHRNA7 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;DRD3;CYP1A1;PPARG GO:0040014| regulation of multicellular organism growth SOD1;DRD3 GO:0001975| response to amphetamine SOD1;CNR2;DRD2;DRD3 GO:0007165| signal transduction CNR1;GPR12;HTR2A;CHRM1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;DRD3;GPR18;PPARG;SMPD1;DRD2;CACNA1I;PLA2G1B GO:0050482| arachidonic acid secretion DRD2;PLA2G1B;DRD3 GO:1900273| DRD2;CHRNA7 GO:0014854| response to inactivity CAT;DRD2 GO:0008283| cell proliferation CYP1A1;CHRM1;HTR1A;GPX1 GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0009636| response to toxin CYP1A1;DRD2;CYP1B1;GPX1;CAT GO:0008285| negative regulation of cell proliferation CYP1B1;DRD2;PPARG;OPRM1;PTGS2 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0045776| negative regulation of blood pressure CNR1;DRD2;DRD3 GO:0045471| response to ethanol DRD3;DRD2;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0048678| response to axon injury SOD1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0007399| nervous system development CHRM1;GLRB;SMPD1 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0001659| temperature homeostasis TRPV1;DRD2;GPX1;HTR2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0048148| behavioral response to cocaine HTR2A;DRD2;DRD3 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0008542| visual learning DRD2;DRD3;HMGCR GO:0001964| startle response DRD2;GLRB;GLRA1 19866:[DB14011 DB00123] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent KARS;PPARG GO:0006810| transport SLC7A4;TRPV2;ABCC1;SLC7A2;CACNA1I;TRPV1;SLC7A1;ABCG2 GO:0034220| ion transmembrane transport TRPA1;GLRA1;GLRB;TRPV1;SLC22A4;GLRA3;CHRNA7 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3;SLC16A10;SLC22A4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;TRPV4;KARS GO:0000187| activation of MAPK activity PLA2G1B;KARS;CHRNA7;SOD1 GO:0010759| positive regulation of macrophage chemotaxis KARS;TRPV4 GO:0050727| regulation of inflammatory response PTGS2;SLC7A2 GO:0016032| viral reproduction HTR2A;VDAC1;KARS GO:0006641| triglyceride metabolic process GPX1;CAT;SLC22A4 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;SLC22A4;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPA1;GLRA1;CACNA1G GO:0006809| nitric oxide biosynthetic process CYP1B1;SLC7A2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;KARS;OPRM1;PTGS2 19867:[DB14011 DB01812] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01812|Adenosine-3'-5'-Diphosphate HS3ST1;SULT2B1;RNASE2;SULT1A1;HS3ST3A1;RNASE1;SULT2A1;SULT1E1;NDST1;acpS;SULT1B1;topA common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;SULT2B1;SULT2A1;CYP2C9;CYP1A1;SULT1E1;CYP17A1;CYP3A5;SULT1B1;CYP2C19;CYP2D6;CYP1B1;SULT1A1 GO:0016042| lipid catabolic process PLA2G1B;DAGLA;NAPEPLD;SULT2A1 GO:0030855| epithelial cell differentiation PPARG;SULT1B1;VDAC1 GO:0008203| cholesterol metabolic process CAT;SULT2B1;HMGCR GO:0009812| flavonoid metabolic process SULT1A1;SULT1B1;CYP1A1 GO:0043312| neutrophil degranulation ALOX5;CAT;RNASE2 GO:0050830| defense response to Gram-positive bacterium RNASE2;PLA2G1B GO:0009308| amine metabolic process CYP1A1;SULT1A1 GO:0008210| estrogen metabolic process SULT1E1;CYP1B1;SULT1A1 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;CNR1;HMGCR;SULT2A1 GO:0045600| positive regulation of fat cell differentiation HTR2A;SULT1E1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2;SULT2B1 GO:0006805| xenobiotic metabolic process CYP3A5;SULT1B1;CYP2D6;CYP2C19;SULT1A1;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0008152| metabolic process NDST1;ACAT1;SMPD1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;SULT2B1;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1;SULT2A1;CYP2C9;PPARG;SULT1A1;TRPV1;PLA2G1B;ALOX15;SULT1B1;CYP2D6;DAGLA GO:0007507| heart development NDST1;PPARG GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;NDST1;PTGS2;CNR2;PTGS1;ALOX5 19868:[DB14011 DB00352] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0051289| protein homotetramerization TRPM8;TRPV1;HPRT1;TRPA1;CRYZ;CAT GO:0001975| response to amphetamine HPRT1;SOD1;CNR2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;ABCC4;AANAT;ACAT1 GO:0002576| platelet degranulation ABCC4;SOD1 GO:0007626| locomotory behavior OPRM1;SOD1;HPRT1 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2;HMGCR GO:0010243| response to organic nitrogen TRPV1;ABCC4;PTGS2 GO:0099133| ABCC4;ABCC1 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;ABCC4;CAT GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1;ABCC4;CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 GO:0010033| response to organic substance ABCC4;PTGS2;CYP1A2;SOD1;TRPA1;CYP1A1;PPARG GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;TRPA1;CACNA1G;ABCC1;TRPV2;ABCC4;CACNA1H;TRPV3 19869:[DB14011 DB03754] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03754|Tromethamine CANT1;NEIL1;AMD1;bioB;VEGFA;pgl;DCN common genes common pathways GO:0007568| aging CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;DCN;CNR1;SOD1;HTR2A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade DCN;CAT GO:0071456| cellular response to hypoxia SLC29A1;VEGFA;PTGS2;OPRD1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0006979| response to oxidative stress NEIL1;SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0030855| epithelial cell differentiation VEGFA;PPARG;VDAC1 GO:0001541| ovarian follicle development VEGFA;SOD1 GO:0045766| positive regulation of angiogenesis VEGFA;CHRNA7;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;OPRM1;VEGFA;HMGCR;GPR55;HTR2A;CHRNA7 GO:0043406| positive regulation of MAP kinase activity HTR2A;VEGFA GO:0001666| response to hypoxia CYP1A1;VEGFA;CHRNA7;CAT GO:0010628| positive regulation of gene expression TRPV4;VEGFA GO:0030324| lung development CYP1A2;VEGFA GO:0042060| wound healing DCN;OPRM1;ALOX15 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;DCN;OPRM1;CYP1A2;CNR2;PTGS2 GO:0043312| neutrophil degranulation CAT;CANT1;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;VEGFA GO:0001822| kidney development DCN;VEGFA;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;DCN GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;VEGFA GO:0002576| platelet degranulation VEGFA;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;VEGFA;PTGS2;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DCN;VEGFA;PLA2G1B;PPARG GO:0030224| monocyte differentiation VEGFA;PPARG GO:0016525| negative regulation of angiogenesis PPARG;DCN GO:0043117| positive regulation of vascular permeability TRPV4;VEGFA GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7;CANT1;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2;OPRD1 GO:0001890| placenta development DCN;SOD1;PPARG GO:0051781| positive regulation of cell division VEGFA;CAT GO:0001525| angiogenesis VEGFA;PTGS2;CYP1B1 GO:0048469| cell maturation VEGFA;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0007399| nervous system development GLRB;SMPD1;VEGFA GO:0008152| metabolic process SMPD1;ACAT1;NEIL1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2;GPX1 GO:0001934| positive regulation of protein phosphorylation VEGFA;CHRNA7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0010629| negative regulation of gene expression VEGFA;OPRD1 GO:0007595| lactation VEGFA;SLC29A1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A 19870:[DB14011 DB00445] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes ABCC1 common pathways GO:0036150| PLA2G1B;PLA2G4A GO:0009395| phospholipid catabolic process PLA2G4A;NAPEPLD GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0050482| arachidonic acid secretion PLA2G4A;PLA2G1B GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;TOP2A;PPARG;CYP1B1;TRPV1;IDO1 GO:0008152| metabolic process SMPD1;PLA2G4A;UGT2B7;ACAT1 GO:0036148| PLA2G1B;PLA2G4A GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process PLA2G4A;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PTGS1;UGT2B7;NAAA;GPX1 GO:0006357| regulation of transcription from RNA polymerase II promoter CHD1;PPARG GO:0036149| PLA2G4A;PLA2G1B GO:0006351| transcription, DNA-dependent CHD1;PPARG GO:0048511| rhythmic process PPARG;TOP2A;AANAT GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G4A;PLA2G1B GO:0016042| lipid catabolic process PLA2G4A;DAGLA;PLA2G1B;NAPEPLD GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0036152| PLA2G4A;PLA2G1B GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;UGT2B7;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1 GO:0006810| transport TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;CYP2D6;DAGLA;ALOX15;PLA2G4A GO:0060326| cell chemotaxis ABCC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CHD1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 GO:0099133| ABCC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G4A;PLA2G1B GO:0042127| regulation of cell proliferation PLA2G4A;PTGS1;PTGS2 GO:0036151| PLA2G1B;PLA2G4A 19871:[DB14011 DB07705] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07705|1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE CYP51A1 common genes common pathways GO:0070988| demethylation CYP1A1;CYP51A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP51A1;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0016125| sterol metabolic process CYP51A1;CYP17A1;CYP1B1 GO:0016126| sterol biosynthetic process CYP51A1;HMGCR GO:0006695| cholesterol biosynthetic process HMGCR;CYP51A1 GO:0008203| cholesterol metabolic process HMGCR;CYP51A1;CAT GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP3A7;CYP51A1;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1A1;CYP2C9;CRYZ GO:0006694| steroid biosynthetic process CYP17A1;CYP51A1;HMGCR GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;HMGCR;CYP51A1;CYP3A7;CYP1A2;CYP3A4 GO:0045540| regulation of cholesterol biosynthetic process CYP51A1;HMGCR 19872:[DB14011 DB08519] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08519|N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0001525| angiogenesis CYP1B1;KDR;PTGS2 GO:0016032| viral reproduction VDAC1;KDR;HTR2A GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;KDR;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;KDR GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;KDR GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;KDR 19873:[DB14011 DB04335] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04335|Inosine PNP;deoD;XDH;SLC28A3 common genes common pathways GO:1901642| SLC28A3;SLC29A1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;XDH;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;PNP;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0022900| electron transport chain CYP1A2;XDH;GSR;IDO1 GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0006919| activation of caspase activity PPARG;XDH GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0007595| lactation SLC29A1;XDH GO:0006955| immune response OPRD1;CNR2;PNP GO:0006195| purine nucleotide catabolic process GPX1;XDH;PNP GO:0010629| negative regulation of gene expression OPRD1;XDH 19874:[DB14011 DB09066] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09066|Corifollitropin alfa FSHR common genes common pathways GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;FSHR;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;FSHR;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FSHR;CAT GO:0007283| spermatogenesis FSHR;SOD1;CNR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;FSHR;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 19875:[DB14011 DB03909] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways GO:0006816| calcium ion transport TRPV3;CACNA1H;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;ATP2A1;TRPM8 GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 GO:0035556| intracellular signal transduction PLA2G1B;INSR GO:0045821| positive regulation of glycolysis INSR;HTR2A GO:0008089| anterograde axon cargo transport SOD1;KIF1A GO:0034976| response to endoplasmic reticulum stress ATP2A1;ALOX15 GO:0045740| positive regulation of DNA replication INSR;PLA2G1B GO:0006811| ion transport TRPM8;ATP2A1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H GO:0008283| cell proliferation GPX1;PDXK;HTR1A;CYP1A1 GO:0070588| calcium ion transmembrane transport TRPM8;ATP2A1;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G;CHRNA7;TRPV2;OPRM1;CACNA1H;TRPV3 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2;INSR GO:0032869| cellular response to insulin stimulus PPARG;INSR;PLA2G1B GO:0016525| negative regulation of angiogenesis PPARG;PGK1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0006355| regulation of transcription, DNA-dependent PPARG;INSR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;INSR GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;INSR GO:0043312| neutrophil degranulation ALOX5;PDXK;CAT GO:0007612| learning VDAC1;INSR;PTGS2 GO:0070509| calcium ion import CACNA1H;CACNA1I;TRPV4;ATP2A1;CACNA1G GO:0034220| ion transmembrane transport ATP2A1;TRPV1;GLRB;TRPA1;GLRA1;CHRNA7;GLRA3 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;INSR GO:0030855| epithelial cell differentiation PPARG;PGK1;VDAC1 GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;INSR;OPRM1;PTGS2 GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;INSR;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1;PGK1 19876:[DB14011 DB07476] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07476|N-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance CA2;PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 19877:[DB14011 DB02152] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02152|K-252a MET;MAP2K1 common genes common pathways GO:0048538| thymus development MAP2K1;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;MAP2K1;ALOX15;TRPV4 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;MAP2K1;CHRNA7 GO:0010628| positive regulation of gene expression MAP2K1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;MET GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MET GO:0007165| signal transduction OPRD1;OPRM1;MET;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;MAP2K1;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0008283| cell proliferation HTR1A;MET;GPX1;CYP1A1 GO:0008285| negative regulation of cell proliferation MAP2K1;OPRM1;PTGS2;CYP1B1;PPARG GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;MET GO:0007507| heart development MAP2K1;PPARG GO:0010629| negative regulation of gene expression OPRD1;MAP2K1 19878:[DB14011 DB03277] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03277|alpha-maltotriose AMY2B common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;AMY2B 19879:[DB14011 DB04875] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04875|Pralnacasan CASP1 common genes common pathways GO:0001666| response to hypoxia CYP1A1;CASP1;CAT;CHRNA7 GO:0006915| apoptotic process CASP1;VDAC1;GPX1 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1;CASP1 GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;CASP1;SMPD1;CACNA1I;PLA2G1B GO:0006919| activation of caspase activity CASP1;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0050727| regulation of inflammatory response PTGS2;CASP1 19880:[DB14011 DB09215] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09215|Droxicam PTGS1;PTGS2 common genes PTGS1;PTGS2 common pathways GO:0009750| response to fructose stimulus PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway GPX1;ALOX5;PTGS2;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT GO:0071284| cellular response to lead ion PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0007568| aging CYP1A1;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:1902219| PTGS2 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:1990776| PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;CNR2;PTGS2;OPRM1;HTR2A;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 19881:[DB14011 DB08205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0006810| transport TRPV2;TTR;ABCC1;TRPV1;CACNA1I;ABCG2 19882:[DB14011 DB05223] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0031000| response to caffeine HDAC1;PPARG;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent HDAC3;HDAC2;HDAC6;HDAC1;PPARG GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;HDAC6;PTGS2;CYP1A2 GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC1 GO:0048511| rhythmic process HDAC2;AANAT;PPARG;HDAC1 GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;PPARG;HDAC1 GO:0010977| negative regulation of neuron projection development TRPV4;HDAC2 GO:0042220| response to cocaine HDAC2;OPRM1;CNR1;SMPD1 GO:1903146| HDAC6;VDAC1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2;HDAC2 GO:0035094| response to nicotine HDAC2;CHRNA7;CNR1 GO:0055093| response to hyperoxia CAT;HDAC2;CYP1A1;HDAC1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;HDAC1;PPARG GO:0006355| regulation of transcription, DNA-dependent HDAC6;HDAC3;HDAC2;HDAC1;PPARG GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;HDAC2;CAT;PPARG;CYP1A1;HDAC1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC3;HDAC2;HDAC1;PPARG;TRPV1;TRPV4 GO:0043066| negative regulation of apoptotic process GPX1;HDAC2;CAT;HDAC3;PTGS2;HMGCR;SOD1;HDAC1 GO:0071300| cellular response to retinoic acid HDAC2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;HDAC1;HDAC2;HDAC3 GO:0008284| positive regulation of cell proliferation HDAC1;PTGS2;HMGCR;HTR1A;HTR2A;HDAC2;CHRNA7 GO:0070848| response to growth factor stimulus HDAC6;OPRM1 GO:0034599| cellular response to oxidative stress SOD1;CAT;GPX1;HDAC1;GSR GO:0032496| response to lipopolysaccharide HDAC2;CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1;HDAC1 GO:0007623| circadian rhythm AANAT;HDAC3 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;HDAC1;PPARG;CYP1B1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;HDAC6;HDAC2 GO:0040029| regulation of gene expression, epigenetic HDAC6;GPX1 GO:0009636| response to toxin HDAC6;GPX1;CAT;CYP1A1;CYP1B1 GO:0001975| response to amphetamine HDAC1;CNR2;SOD1;HDAC2 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HDAC3;CNR1;HMGCR GO:0071498| cellular response to fluid shear stress PTGS2;HDAC3 GO:0016032| viral reproduction HDAC1;VDAC1;HTR2A GO:0001934| positive regulation of protein phosphorylation HDAC3;CHRNA7 GO:0048149| behavioral response to ethanol HDAC2;OPRM1 GO:0043524| negative regulation of neuron apoptosis SOD1;HDAC1 GO:0010629| negative regulation of gene expression HDAC1;OPRD1 GO:0006351| transcription, DNA-dependent HDAC1;PPARG;HDAC3;HDAC2;HDAC6 GO:0045598| regulation of fat cell differentiation HDAC6;PPARG 19883:[DB14011 DB03788] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03788|GC-24 THRB common genes common pathways GO:0043401| steroid hormone mediated signaling pathway PPARG;THRB GO:0006351| transcription, DNA-dependent PPARG;THRB GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;THRB GO:0008016| regulation of heart contraction CACNA1H;THRB GO:0045892| negative regulation of transcription, DNA-dependent THRB;PPARG GO:0007605| sensory perception of sound GPX1;SOD1;THRB GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;THRB GO:0006355| regulation of transcription, DNA-dependent PPARG;THRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;THRB;TRPV1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;THRB;PPARG 19884:[DB14011 DB11148] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11148|Butamben CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;BCHE;ORM1;ALB common genes CACNA1G;CACNA1I;CACNA1H common pathways GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;KCNJ11 GO:0086018| CACNA1G GO:0086027| CACNA1G GO:0006810| transport CACNA1B;TRPV2;CACNB4;CACNG1;ABCC1;CACNB3;CACNA1I;TRPV1;CACNB1;ABCG2 GO:0098869| GSR;ALB;PTGS2;PTGS1;GPX1;CAT GO:0006936| muscle contraction CACNG1;CACNA1H;KCNJ12;CACNA1S;GLRA1 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;KCNJ10;KCNJ11;CACNA1H GO:0032720| negative regulation of tumor necrosis factor production ORM1;GPR18;CHRNA7 GO:0007605| sensory perception of sound CACNA1D;GPX1;SOD1 GO:0008219| cell death HTR2A;CACNA1A GO:0055085| transmembrane transport KCNJ11;CACNA1B;CACNA1H;TRPV3;TRPV2;CACNA1D;CACNA1C;TRPA1;CACNA1S;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;CACNA1I;CACNA1A;CACNA1F GO:0086002| CACNA1D;CACNA1C;CACNA2D1;CACNA1G GO:0071356| cellular response to tumor necrosis factor KCNJ11;TRPV1 GO:0007612| learning PTGS2;VDAC1;BCHE GO:0001508| regulation of action potential CACNA1G;GLRA1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;KCNJ8;CNR2;PTGS2;CYP1A2;OPRM1 GO:0070509| calcium ion import CACNA1I;TRPV4;CACNA1G;CACNA1D;CACNA1H;CACNB2 GO:0007269| neurotransmitter secretion NAAA;CACNA1B GO:0030317| sperm motility CACNA1I GO:0071333| cellular response to glucose stimulus SLC29A1;KCNJ11 GO:0086016| CACNA1G GO:0042311| vasodilation GPX1;KCNJ8 GO:0001822| kidney development KCNJ8;CAT GO:0086015| CACNA1G GO:0043066| negative regulation of apoptotic process ALB;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0002576| platelet degranulation ORM1;ALB;SOD1 GO:0007626| locomotory behavior CACNA1B;SOD1;OPRM1 GO:0010045| response to nickel cation CACNA1G GO:0043312| neutrophil degranulation ORM1;CAT;ALOX5 GO:0007628| adult walking behavior KCNJ10;GLRB;GLRA1 GO:0007517| muscle organ development CACNA1H GO:0042493| response to drug PPARG;CYP1A1;TRPA1;BCHE;ABCC1;SMPD1;ABCG2;KCNJ11;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0032342| aldosterone biosynthetic process CACNA1H GO:0048265| response to pain TRPA1;TRPV1;CACNA1B GO:0040014| regulation of multicellular organism growth SOD1;CACNA2D2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0007601| visual perception CRYZ;GLRA1;CACNA1F;CYP1B1;GLRB;CACNB2;KCNJ10 GO:0007520| myoblast fusion CACNA1H GO:0050796| regulation of insulin secretion CACNA1C;CACNA1D;CNR1;KCNJ11;CACNA1A;CACNA2D2 GO:0007204| elevation of cytosolic calcium ion concentration CACNA1A;TRPV4;TRPV1;HTR2A;OPRM1;CACNA1C GO:0032870| cellular response to hormone stimulus CACNA1H GO:1904645| CHRNA7;CACNA1A GO:0043010| camera-type eye development CACNA1C;CYP1A1 GO:0034765| regulation of ion transmembrane transport KCNJ15;CACNB3;CACNA2D2;CACNA1S;CACNA1G;KCNJ1;CACNB1;CACNA2D3;CACNA1I;CACNA1A;CACNA1F;CACNB2;KCNJ11;CACNA2D1;CACNA1B;CACNA1H;KCNJ14;KCNJ12;KCNJ8;KCNJ10;CACNG1;CACNB4;CACNA1D;CACNA1C GO:0070588| calcium ion transmembrane transport CACNB3;TRPA1;CACNA2D2;CACNA1S;CACNA1G;CACNB1;CACNA2D3;TRPM8;TRPV4;CACNA1I;CACNA1A;TRPV1;CACNA1F;CACNB2;CACNA2D1;CACNA1B;OPRM1;CACNA1H;TRPV3;CHRNA7;CACNG1;CACNA1D;TRPV2;CACNB4;CACNA1C GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CACNA1G;CACNA1I GO:2000344| positive regulation of acrosome reaction GLRA1;CACNA1H GO:0006811| ion transport CACNA1B;GLRA3;CACNB2;KCNJ11;CACNA2D1;TRPV3;KCNJ8;KCNJ12;CACNA1H;KCNJ14;KCNJ10;CACNG1;CHRNA7;CACNA1C;CACNA1D;TRPV2;CACNB4;TRPA1;GLRA1;CACNB3;CACNA2D2;KCNJ15;CACNA1S;CACNA1G;CACNA2D3;TRPM8;CACNB1;KCNJ1;CACNA1F;TRPV4;GLRB;CACNA1I;VDAC1;CACNA1A;TRPV1 GO:0086045| CACNA1C;CACNB2;CACNA1G GO:0001895| retina homeostasis SOD1;ALB GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G GO:0050896| response to stimulus TRPA1;CACNA1F;TRPM8 GO:0008285| negative regulation of cell proliferation PPARG;BCHE;CYP1B1;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PPARG;PTGS1;CACNA1B;SOD1;PTGS2 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0086046| CACNA1D;CACNA1G GO:0086091| CACNB2;CACNA2D1;CACNA1D;CACNA1C;CACNA1G GO:0008016| regulation of heart contraction KCNJ12;CACNA1H;CACNA1B GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;CACNA1H GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0098662| CACNA1H GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CACNA1D;CNR1 GO:0007507| heart development PPARG;CACNA1C;KCNJ8 GO:0002027| regulation of heart rate CACNA1G GO:0007268| synaptic transmission CACNA1G;CACNB3;GLRA1;VDAC1;GLRB;CACNB1;OPRD1;OPRM1;GLRA3;CACNA1B;HTR2A;CACNB2;CACNB4 GO:0098703| CACNA2D1;TRPV1 GO:0006816| calcium ion transport CACNA1G;CACNA1S;CACNA2D2;TRPA1;CACNB3;CACNA1F;CACNA1A;CACNA1I;TRPV4;TRPV1;CACNA2D3;TRPM8;CACNB1;TRPV3;CACNA1H;CACNA1B;CACNA2D1;CACNB2;CACNA1C;CACNA1D;CACNB4;TRPV2;CACNG1;CHRNA7 GO:0051289| protein homotetramerization TRPV1;TRPM8;CRYZ;TRPA1;CAT;KCNJ12 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;ALOX15;IDO1;ORM1 GO:0034651| cortisol biosynthetic process CACNA1H GO:0009268| response to pH KCNJ8;TRPV1 GO:0086010| CACNA1H;CACNA1B;CACNA1G;CACNA1S;CACNA1A;CACNA1I;CACNA1F GO:0051924| regulation of calcium ion transport OPRD1;CACNA2D1;CACNA1B 19885:[DB14011 DB02678] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways GO:0006915| apoptotic process VDAC1;LGALS7;GPX1 19886:[DB14011 DB12698] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD4 GO:0010524| positive regulation of calcium ion transport into cytosol CD4;PLA2G1B GO:0007155| cell adhesion CYP1B1;CD4 GO:0009615| response to virus CYP1A1;CXCR4 GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B;CXCR4 GO:0006915| apoptotic process CXCR4;VDAC1;GPX1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HMGCR;CD4;OPRM1;HTR2A;GPR55;TRPV4;ALOX15 GO:0048714| positive regulation of oligodendrocyte differentiation CXCR4;PPARG GO:0001666| response to hypoxia CYP1A1;CXCR4;CAT;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CXCR4;GPR18;CCR5;PPARG GO:0032355| response to estradiol stimulus CD4;PTGS2;CYP1A2;CAT GO:0002376| immune system process IDO1;CD4 GO:0001934| positive regulation of protein phosphorylation CD4;CHRNA7 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD4;HTR2A GO:0051924| regulation of calcium ion transport CD4;OPRD1 GO:0033674| positive regulation of kinase activity HTR2A;CD4 GO:0006955| immune response CD4;CNR2;OPRD1;CCR5 GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;CCR5;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;TRPV3 GO:0016032| viral reproduction HTR2A;CD4;CCR5;CXCR4;VDAC1 GO:0030217| T cell differentiation CD4;GPR18 GO:0006954| inflammatory response CCR5;ALOX15;CXCR4;IDO1;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0007166| cell surface receptor linked signaling pathway CCR5;TRPA1;TRPV1;CD4 GO:0033280| response to vitamin D PTGS2;CD4 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;CXCR4;CCR5;OPRM1;HTR2A GO:0071345| cellular response to cytokine stimulus TRPV1;CXCR4 GO:0007165| signal transduction GPR18;PPARG;CCR5;SMPD1;CXCR4;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CD4;CNR2;CHRNA7 19887:[DB14011 DB01597] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0071277| cellular response to calcium ion ALOX15;DPEP1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;DPEP1;CYP1A2;CYP3A4;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process DPEP1;PTGS2;GPX1 GO:0006811| ion transport TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;SLC22A8;GLRA3;CACNA1H;TRPV3 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;GPX1;CAT GO:0030336| negative regulation of cell migration CYP1B1;DPEP1 GO:0006749| glutathione metabolic process GSR;GPX1;SOD1;DPEP1 GO:0098656| SLC22A6;VDAC1;SLC22A8 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;DPEP1;PTGS2;SOD1 GO:0006691| leukotriene metabolic process DPEP1;ALOX5;ABCC1;ALOX15 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0055085| transmembrane transport VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1G;SLC22A6;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;SLC22A8 GO:0006915| apoptotic process VDAC1;DPEP1;GPX1 19888:[DB14011 DB04048] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;PRDX2;HMGCR;PTGS2;CAT;GPX1 GO:0034599| cellular response to oxidative stress SOD1;PRDX2;CAT;GPX1;GSR GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;PRDX2;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0006979| response to oxidative stress SOD1;PRDX2;PTGS2;CAT;PTGS1;GPX1 GO:0042744| hydrogen peroxide catabolic process PRDX2;GPX1;CAT GO:0019430| removal of superoxide radicals PRDX2;SOD1 GO:0045454| cell redox homeostasis GSR;GPX1;PRDX2 19889:[DB14011 DB00464] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00464|Sodium Tetradecyl Sulfate PROC;PROS1 common genes common pathways GO:0002576| platelet degranulation SOD1;PROS1 GO:0043066| negative regulation of apoptotic process GPX1;PROC;CAT;PTGS2;HMGCR;SOD1 GO:0050728| negative regulation of inflammatory response CNR2;PROC GO:0001889| liver development PROC;ACAT1;CYP1A1 19890:[DB14011 DB01709] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CYP1A1;ENO3 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;ENO3;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0043403| skeletal muscle tissue regeneration ENO3;GPX1 19891:[DB14011 DB00031] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0042060| wound healing SERPINB2;ALOX15;OPRM1 GO:0007623| circadian rhythm AANAT;SERPINE1 GO:0030199| collagen fibril organization CYP1B1;ANXA2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;SERPINB2;PLAUR GO:0035722| interleukin-12-mediated signaling pathway SERPINB2;CANX;SOD1;ANXA2 GO:0002576| platelet degranulation SERPINE1;SOD1;FGA;CLEC3B;PLG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;SERPINE1 GO:0008284| positive regulation of cell proliferation CALR;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0043312| neutrophil degranulation ANXA2;ALOX5;CAT;PLAUR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;CALR GO:0045087| innate immune response PPARG;FGA GO:0042493| response to drug TRPA1;CYP1A1;PPARG;CALR;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0051702| interaction with symbiont PLG;GPX1 GO:0033629| negative regulation of cell adhesion mediated by integrin SERPINE1;CYP1B1 GO:0032355| response to estradiol stimulus CALR;CYP1A2;PTGS2;CAT GO:0007568| aging SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;LRP1;CANX GO:0030282| bone mineralization PTGS2;CLEC3B;ALOX15 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPV4;TRPM8;CALR GO:0043388| positive regulation of DNA binding PPARG;PLAUR GO:0002376| immune system process FGA;IDO1 GO:0050714| positive regulation of protein secretion FGA;PLA2G1B GO:0045766| positive regulation of angiogenesis SERPINE1;CHRNA7;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;FGA;TRPV4;ALOX15 GO:0010977| negative regulation of neuron projection development LRP1;TRPV4 GO:0010628| positive regulation of gene expression CALR;TRPV4 GO:0007283| spermatogenesis CALR;SOD1;CNR1 GO:0043277| apoptotic cell clearance ALOX15;LRP1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CALR;CYP1A1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent CALR;PPARG GO:0061045| negative regulation of wound healing SERPINE1;HMGCR GO:0051592| response to calcium ion AANAT;FGA GO:0001525| angiogenesis CYP1B1;SERPINE1;ANXA2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1;LRP1;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0042953| lipoprotein transport PPARG;LRP1 GO:0001503| ossification CLEC3B;ALOX15 GO:0043524| negative regulation of neuron apoptosis SOD1;LRP1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ANXA2;PLAUR GO:0016032| viral reproduction KRT8;HTR2A;VDAC1 GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0050729| positive regulation of inflammatory response SERPINE1;TRPV4 GO:0045907| positive regulation of vasoconstriction FGA;PTGS2;HTR2A GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;FGA;PLAUR GO:0034116| positive regulation of heterotypic cell-cell adhesion FGA;ALOX15 GO:0008283| cell proliferation LRP1;CYP1A1;HTR1A;GPX1 GO:0001523| retinoid metabolic process LRP1;NAPEPLD GO:0045740| positive regulation of DNA replication CALR;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ANXA2 GO:0030336| negative regulation of cell migration CYP1B1;SERPINE1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PLG;PPARG;CYP1B1 GO:1902042| FGA;GPX1;SERPINE1 19892:[DB14011 DB00095] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00095|Efalizumab ITGAL;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction GPR55;HTR1A;ITGAL;HTR2A;GPR12;CNR1;CNR2;OPRM1;FCGR2C;OPRD1;CHRNA7;FCGR2B;PPARG;GPR18;SMPD1;FCGR1A;CACNA1I;PLA2G1B GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 GO:0016032| viral reproduction HTR2A;VDAC1;FCGR2B GO:0006955| immune response CNR2;OPRD1;FCGR2C;FCGR3A;C1QC;FCGR1A;C1R;FCGR2B;FCGR3B GO:0006954| inflammatory response FCGR2B;IDO1;ALOX15;TRPV1;ITGAL;PTGS2;CNR2;ALOX5;PTGS1 GO:0002376| immune system process FCGR2A;FCGR1A;IDO1;C1QB;C1R;C1QA;C1QC GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0043312| neutrophil degranulation ITGAL;ALOX5;CAT;FCGR3B;FCGR2A GO:0007155| cell adhesion ITGAL;CYP1B1 GO:0045087| innate immune response FCGR1A;C1R;C1QB;PPARG;C1QA;C1QC 19893:[DB14011 DB09526] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09526|Hydroquinone TYR;ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0009411| response to UV TYR;CAT GO:0033280| response to vitamin D PTGS2;TYR GO:0008283| cell proliferation GPX1;TYR;HTR1A;CYP1A1 GO:0007601| visual perception TYR;CRYZ;GLRA1;CYP1B1;GLRB GO:0008152| metabolic process TYR;ACAT1;SMPD1 GO:0051591| response to cAMP AANAT;TYR GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR;ALB GO:0048538| thymus development SOD1;TYR GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9;ALOX5;GPX1;PTGS1;TYR;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0002576| platelet degranulation SOD1;ALB 19894:[DB14011 DB07456] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways GO:0045766| positive regulation of angiogenesis PDPK1;CYP1B1;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1 GO:0032869| cellular response to insulin stimulus PPARG;PDPK1;PLA2G1B GO:0035556| intracellular signal transduction PLA2G1B;PDPK1 GO:0006351| transcription, DNA-dependent PPARG;PDPK1 GO:0043524| negative regulation of neuron apoptosis PDPK1;SOD1 19895:[DB14011 DB08467] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;CRABP2 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CRABP2;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I 19896:[DB14011 DB08304] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08304|(3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide GRIA2 common genes common pathways GO:0034220| ion transmembrane transport GRIA2;CHRNA7;GLRA3;GLRB;TRPV1;TRPA1;GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;GRIA2;SLC29A1;GLRA1;TRPV1;GLRB GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;GRIA2;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;GRIA2;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;GRIA2;CACNA1G;GLRA1;GLRB;VDAC1 19897:[DB14011 DB00642] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes SLC29A1 common pathways GO:0007595| lactation SLC29A1 GO:0015858| nucleoside transport SLC29A1 GO:0015862| uridine transport SLC29A1 GO:0008152| metabolic process ACAT1;ATIC;GART;SMPD1 GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0045471| response to ethanol TYMS;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0098656| VDAC1;SLC22A8 GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;PPARG;CYP1A1;TYMS;TRPA1 GO:0009636| response to toxin CYP1B1;CYP1A1;TYMS;GPX1;CAT;SLC22A8 GO:0006139| nucleobase-containing compound metabolic process ATIC;SLC29A1;DCK GO:0006811| ion transport VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;SLC22A8 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0033189| response to vitamin A CAT;PPARG;CYP1A1;TYMS GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;DHFR;CRYZ;CYP2C9;CYP1A1 GO:0042493| response to drug ABCG2;CYP1A1;TYMS;PPARG;TRPA1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0034097| response to cytokine stimulus TYMS;AANAT;PTGS2 GO:0032259| methylation TYMS;CYP1A2 GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0007623| circadian rhythm TYMS;AANAT GO:0010033| response to organic substance PPARG;CYP1A1;GART;TRPA1;SOD1;CYP1A2;PTGS2 GO:0055085| transmembrane transport TRPV2;SLC22A8;CACNA1H;TRPV3;ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0031100| organ regeneration ATIC;PPARG GO:0007568| aging CYP1A1;TYMS;CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1 GO:1901642| SLC29A1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 19898:[DB14011 DB09027] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09027|Ledipasvir ABCB1;ABCG2 common genes ABCG2 common pathways GO:0006810| transport TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I;ABCB1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0033344| cholesterol efflux ABCG2 GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCB1;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0015886| heme transport ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0046415| urate metabolic process ABCG2 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 19899:[DB14011 DB04389] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04389|Ado-P-Ch2-P-Ps-Ado FHIT common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;FHIT GO:0006355| regulation of transcription, DNA-dependent PPARG;FHIT GO:0006915| apoptotic process VDAC1;FHIT;GPX1 19900:[DB14011 DB03013] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03013|Di(N-Acetyl-D-Glucosamine) LYZ;B4GALT1 common genes common pathways GO:0051260| protein homooligomerization GLRA1;B4GALT1;ACAT1;GLRA3 GO:0043312| neutrophil degranulation B4GALT1;LYZ;CAT;ALOX5 GO:0007155| cell adhesion B4GALT1;CYP1B1 GO:0042060| wound healing ALOX15;B4GALT1;OPRM1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;B4GALT1 GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B GO:0060055| angiogenesis involved in wound healing B4GALT1;GPX1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;B4GALT1;CYP1B1 GO:0001895| retina homeostasis SOD1;LYZ GO:0008152| metabolic process LYZ;SMPD1;ACAT1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;B4GALT1;SMPD1;PPARG GO:0006954| inflammatory response TRPV1;LYZ;ALOX15;IDO1;CNR2;PTGS2;ALOX5;PTGS1 19901:[DB14011 DB08654] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08654|TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 19902:[DB14011 DB08416] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08416|(9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE CA2 common genes common pathways GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0010033| response to organic substance CA2;CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0001822| kidney development CA2;CAT 19903:[DB14011 DB01207] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0045777| positive regulation of blood pressure CNR1;TBXA2R GO:0001516| prostaglandin biosynthetic process TBXAS1;PTGS1;PTGS2 GO:0007584| response to nutrient CNR1;HMGCR;TBXA2R;PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2;TBXA2R GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TBXA2R;TRPV4;TRPV1 GO:0065009| regulation of molecular function TBXA2R;TRPV1 GO:0006633| fatty acid biosynthetic process PLA2G1B;TBXAS1;PTGS1;PTGS2 GO:0007165| signal transduction TBXA2R;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;TBXA2R GO:0019371| cyclooxygenase pathway PTGS1;PTGS2;TBXAS1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;CNR2;PTGS2;ALOX5;PTGS1;TBXA2R GO:0045471| response to ethanol TBXA2R;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;TBXAS1;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;PTGS1;NAAA;GPX1 GO:0006693| prostaglandin metabolic process TBXAS1;PTGS2;PTGS1 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;TBXA2R GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;TBXA2R;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;CYP3A5;ALOX15;TBXAS1;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0006631| fatty acid metabolic process TBXAS1;ALOX15;PTGS1;PTGS2 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;TBXA2R;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;TBXA2R;CNR1;OPRM1;CYP1A2;PTGS2;CNR2 19904:[DB14011 DB00043] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MS4A2;TRPA1;TRPV1 GO:0006954| inflammatory response ALOX5;PTGS1;MS4A2;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0006955| immune response MS4A2;CNR2;OPRD1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;MS4A2;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B 19905:[DB14011 DB02367] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02367|(1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine MMP3 common genes common pathways 19906:[DB14011 DB01194] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes CYP3A4 common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0001822| kidney development CA2;CAT GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1;CA2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;CA3;PTGS2 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0045471| response to ethanol CNR1;SOD1;CA3;HMGCR;OPRM1;CAT GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 19907:[DB14011 DB09343] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;SLC22A2;TRPM8;CACNA1H;TRPV3;TRPV2;SLC47A1 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0006812| cation transport TRPM8;SLC22A2 GO:0006811| ion transport TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;SLC22A2;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCG2;SLC47A1 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0008152| metabolic process TYMP;ACAT1;SMPD1 GO:0001525| angiogenesis PTGS2;TYMP;CYP1B1 19908:[DB14011 DB08608] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08608|4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE PDK2 common genes common pathways GO:0042593| glucose homeostasis PDK2;CNR1;TRPV4;PPARG 19909:[DB14011 DB00974] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0016125| sterol metabolic process CYP19A1;CYP17A1;CYP1B1 GO:0042542| response to hydrogen peroxide TRPA1;ADA;GPX1;CAT;SOD1 GO:0001889| liver development ADA;ACAT1;CYP1A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0001890| placenta development PPARG;ADA;SOD1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0009636| response to toxin CYP1A1;CYP1B1;PON3;GPX1;CAT GO:0043066| negative regulation of apoptotic process CAT;ADA;GPX1;SOD1;HMGCR;PTGS2 GO:0007155| cell adhesion ADA;CYP1B1 GO:0033197| response to vitamin E ADA;CAT GO:0030324| lung development CYP1A2;ADA GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;PON3;ALOX15 GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;CYP19A1 GO:0050728| negative regulation of inflammatory response CNR2;ADA GO:0043278| response to morphine ADA;OPRM1;CNR1 GO:0022900| electron transport chain CYP1A2;CYP19A1;IDO1;GSR GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;CAT;ADA;HTR2A;SOD1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP19A1;CRYZ GO:0007568| aging HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;ADA;CAT;CYP1A1 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;ADA 19910:[DB14011 DB00240] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;NR3C1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;TRPV4;TRPV1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP1A1 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0036378| CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 19911:[DB14011 DB05282] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05282|MCC AIFM1 common genes common pathways GO:0010942| positive regulation of cell death AIFM1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;AIFM1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0009636| response to toxin CYP1A1;CYP1B1;GPX1;CAT;AIFM1 GO:0006919| activation of caspase activity PPARG;AIFM1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;AIFM1 GO:0055114| oxidation-reduction process CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;AIFM1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0006915| apoptotic process VDAC1;AIFM1;GPX1 19912:[DB14011 DB05249] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05249|FavId CSF3R common genes common pathways GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;CSF3R;GPR18;SMPD1 GO:0007155| cell adhesion CYP1B1;CSF3R GO:0030593| neutrophil chemotaxis PLA2G1B;CSF3R 19913:[DB14011 DB08448] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;DHFR;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6 19914:[DB14011 DB03690] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways GO:0035722| interleukin-12-mediated signaling pathway PITPNA;SOD1 GO:0007601| visual perception PITPNA;CRYZ;GLRA1;CYP1B1;GLRB GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;CYP1A2;PITPNA;PTGS2;HMGCR;NAPEPLD;CYP3A4 19915:[DB14011 DB04588] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04588|N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0009408| response to heat HSP90AA1;TRPV1;TRPV3;SOD1;TRPV2 GO:0009409| response to cold TRPA1;HSP90AA1;PPARG;TRPM8 GO:0007165| signal transduction SMPD1;GPR18;PPARG;HSP90AA1;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HSP90AA1;PTGS2;OPRM1 19916:[DB14011 DB02850] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;HPD;CRYZ;CYP2C9;CYP1A1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 19917:[DB14011 DB03608] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03608|Diminazene PRDX5;PRSS1;AOC1 common genes common pathways GO:0071280| cellular response to copper ion CYP1A1;AOC1;CYP1A2 GO:0098869| GPX1;PTGS1;CAT;PTGS2;PRDX5;GSR GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;PRDX5;SOD1 GO:0009235| cobalamin metabolic process PRSS1;ABCC1 GO:0006915| apoptotic process PRDX5;GPX1;VDAC1 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;PRDX5 GO:0043312| neutrophil degranulation AOC1;ALOX5;CAT GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;PRDX5;GPX1;CAT GO:0046677| response to antibiotic AOC1;CYP1A1;SOD1 GO:0034599| cellular response to oxidative stress GPX1;CAT;PRDX5;SOD1;GSR GO:0009308| amine metabolic process CYP1A1;AOC1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;PRDX5;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;AOC1 GO:0042493| response to drug PPARG;CYP1A1;AOC1;TRPA1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0045454| cell redox homeostasis GSR;GPX1;PRDX5 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;AOC1;CYP2C9 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;PRDX5;TRPV1;ALOX15;IDO1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PRDX5;PTGS2;GPX1 19918:[DB14011 DB06600] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06600|Nemonoxacin CYP1A2 common genes CYP1A2 common pathways GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;IDO1;CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1A1;CYP2C9;CRYZ;ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9;PTGS1;NAAA;GPX1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 19919:[DB14011 DB06497] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06497|Aplaviroc CCR5 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;CCR5;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;CCR5;TRPV1;TRPV4 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;CCR5;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0007166| cell surface receptor linked signaling pathway TRPA1;CCR5;TRPV1 GO:0006816| calcium ion transport CACNA1H;TRPV3;TRPV2;CHRNA7;CACNA1G;CCR5;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8 GO:0016032| viral reproduction HTR2A;CCR5;VDAC1 GO:0006955| immune response CNR2;OPRD1;CCR5 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;ALOX15;IDO1;TRPV1;CCR5 19920:[DB14011 DB08707] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08707|4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PIM1;HMGCR;SOD1;GPX1;CAT GO:0006915| apoptotic process PIM1;GPX1;VDAC1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;PIM1 19921:[DB14011 DB07717] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways GO:0006810| transport TRPV2;AR;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0010468| regulation of gene expression CYP1A2;AR GO:0007283| spermatogenesis AR;SOD1;CNR1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0008284| positive regulation of cell proliferation AR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;TRPV1;TRPV4;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;AR;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0008285| negative regulation of cell proliferation AR;OPRM1;PTGS2;CYP1B1;PPARG GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;AR GO:0007548| sex differentiation AR;CYP17A1 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AR GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT 19922:[DB14011 DB00846] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes CYP3A4 common pathways GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;TRPV4;TRPV1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PLA2G1B;PPARG GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0006915| apoptotic process VDAC1;GPX1;NR3C1 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;NR3C1;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 19923:[DB14011 DB03243] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03243|4-Fluorobenzylamine PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 19924:[DB14011 DB04585] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04585|DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID ARG1 common genes common pathways GO:0001889| liver development ARG1;ACAT1;CYP1A1 GO:0048678| response to axon injury ARG1;SOD1 GO:0009635| response to herbicide ARG1;CYP1A1 GO:0007565| female pregnancy IDO1;ARG1 GO:0043434| response to peptide hormone stimulus ARG1;TRPV1 GO:0010043| response to zinc ion ARG1;AANAT GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;ARG1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ARG1 GO:0010269| response to selenium ion GPX1;ARG1 GO:0070207| protein homotrimerization TRPM8;ARG1 GO:0043312| neutrophil degranulation CAT;ARG1;ALOX5 GO:0045087| innate immune response PPARG;ARG1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E ARG1;CAT GO:0032496| response to lipopolysaccharide ARG1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0030324| lung development ARG1;CYP1A2 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0033189| response to vitamin A ARG1;CAT;CYP1A1;PPARG GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;ARG1;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0002376| immune system process IDO1;ARG1 GO:0009611| response to wounding ARG1;GPX1;CYP1A1 GO:0007568| aging ARG1;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CYP1A1 GO:0042130| negative regulation of T cell proliferation ARG1;IDO1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ARG1 GO:0046686| response to cadmium ion CAT;ARG1 19925:[DB14011 DB01125] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01125|Anisindione GGCX common genes common pathways 19926:[DB14011 DB02205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02205|6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One GAPDHS common genes common pathways GO:0030317| sperm motility GAPDHS;CACNA1I GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;GAPDHS;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6 GO:0045821| positive regulation of glycolysis GAPDHS;HTR2A 19927:[DB14011 DB04175] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04175|Mdl-29951 FBP1 common genes common pathways GO:0030308| negative regulation of cell growth PPARG;FBP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;FBP1 GO:0008152| metabolic process SMPD1;FBP1;ACAT1 GO:0051289| protein homotetramerization TRPV1;TRPM8;TRPA1;CRYZ;FBP1;CAT 19928:[DB14011 DB01606] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0055085| transmembrane transport SLC22A6;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8;CACNA1H;TRPV3;SLC22A8;TRPV2 GO:0006811| ion transport CHRNA7;TRPV2;SLC22A8;GLRA3;TRPV3;CACNA1H;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPA1;GLRA1;CACNA1G GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0098656| SLC22A8;VDAC1;SLC22A6 19929:[DB14011 DB00006] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00006|Bivalirudin F2;MPO common genes common pathways GO:0061844| F2;PLA2G1B GO:0019430| removal of superoxide radicals SOD1;MPO GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;MPO;PTGS1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;F2;GPR18;PPARG GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007568| aging CAT;MPO;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0032094| response to food CYP1A1;MPO;OPRM1 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;MPO;PTGS1;GPX1;CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 GO:0009612| response to mechanical stimulus PPARG;TRPV4;MPO GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;MPO;GPX1 GO:0043312| neutrophil degranulation CAT;MPO;ALOX5 GO:0032496| response to lipopolysaccharide MPO;CNR2;PTGS2;OPRM1;CYP1A2;CNR1;IDO1;CYP1A1 19930:[DB14011 DB00360] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00360|Sapropterin PAH;NOS3;TH;TPH1;PTGS2 common genes PTGS2 common pathways GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0046219| indolalkylamine biosynthetic process AANAT;TPH1 GO:0031667| response to nutrient levels SOD1;TH GO:0009635| response to herbicide TH;CYP1A1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS1;ALOX5;PTGS2;CNR2 GO:0010942| positive regulation of cell death PTGS2 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;NOS3 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;TRPA1;TRPV1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;TH;CAT GO:0008016| regulation of heart contraction CACNA1H;TH GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1 GO:0007507| heart development TH;PPARG GO:0030728| ovulation PTGS2 GO:0042136| neurotransmitter biosynthetic process TH;PAH;DAGLA GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:1990776| PTGS2 GO:0008152| metabolic process ACAT1;SMPD1;PAH GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0071312| cellular response to alkaloid TRPV1;TH GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0014070| response to organic cyclic compound TH;CYP1A2;PTGS2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0042755| eating behavior TH;OPRD1;OPRM1 GO:0014823| response to activity TH;CAT GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;NOS3;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;NOS3;PPARG GO:1902042| GPX1;NOS3 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0010043| response to zinc ion TH;AANAT GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;TPH1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1;TH GO:0007613| memory TH;HTR2A;CNR1;PTGS2;CHRNA7 GO:0033076| isoquinoline alkaloid metabolic process TH;CYP2D6 GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0001975| response to amphetamine SOD1;TH;CNR2 GO:0043434| response to peptide hormone stimulus TH;TRPV1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0050890| cognition TH;CHRNA7 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0051412| response to corticosterone stimulus TH;AANAT GO:0034644| cellular response to UV PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0055114| oxidation-reduction process CYP1B1;TPH1;CYP2D6;NOS3;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;PAH;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;TH;CYP3A4 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0035900| response to isolation stress NAPEPLD;TH GO:0006631| fatty acid metabolic process TH;PTGS2;PTGS1;ALOX15 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;HTR2A;TH;SOD1;CYP1A2;PTGS2 GO:0035094| response to nicotine CHRNA7;CNR1;TH GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071333| cellular response to glucose stimulus SLC29A1;TH GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development CYP1A2;NOS3 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1;TH GO:0007612| learning VDAC1;TH;PTGS2 GO:0007623| circadian rhythm AANAT;TPH1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0035902| response to immobilization stress CYP1A2;TH;TPH1;PPARG;CYP1A1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0042311| vasodilation NOS3;GPX1 GO:0007626| locomotory behavior SOD1;TH;OPRM1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0070848| response to growth factor stimulus OPRM1;TH GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0009416| response to light stimulus AANAT;TH GO:0001666| response to hypoxia TH;CHRNA7;CAT;CYP1A1 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CYP1A1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| PTGS2;HMGCR GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:1902219| PTGS2 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TH;TRPV1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;TH GO:0007605| sensory perception of sound SOD1;TH;GPX1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 19931:[DB14011 DB03191] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03191|3-Oxiran-2ylalanine MAT1A common genes common pathways GO:0051289| protein homotetramerization TRPM8;TRPV1;MAT1A;TRPA1;CRYZ;CAT GO:0032259| methylation CYP1A2;MAT1A 19932:[DB14011 DB06909] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways GO:0007165| signal transduction OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;PDE4B GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;PDE4B;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4B 19933:[DB14011 DB00851] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes CYP1A1;CYP1A2 common pathways GO:0017143| insecticide metabolic process CYP1A1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0045333| cellular respiration CYP1A2 GO:0009636| response to toxin GPX1;CAT;CYP1B1;CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0009624| response to nematode CYP1A1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0043010| camera-type eye development CYP1A1 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:1900087| CYP1A1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0032502| developmental process CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0009635| response to herbicide CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0009403| toxin biosynthetic process CYP1A2 GO:0009692| ethylene metabolic process CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0000060| protein import into nucleus, translocation OPRD1;POLA2 GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CYP2E1;CAT GO:0070988| demethylation CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:0010193| response to ozone CYP2E1;CAT GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0071615| oxidative deethylation CYP1A2 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0010041| response to iron(III) ion CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0009611| response to wounding CYP1A1;GPX1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP2E1;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CYP1A1 GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0009308| amine metabolic process CYP1A1 GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;CYP2E1;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0032094| response to food OPRM1;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;PGD;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1;CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1 GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP2E1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;CYP1A1;IDO1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 19934:[DB14011 DB03598] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03598|Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide] CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;CYP1A1;PPARG;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 19935:[DB14011 DB12095] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;TPH1;TPH2;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6 GO:0007623| circadian rhythm TPH2;TPH1;AANAT GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;TPH1 GO:0046219| indolalkylamine biosynthetic process AANAT;TPH2;TPH1 GO:0031667| response to nutrient levels SOD1;TPH2 GO:0051592| response to calcium ion TPH2;AANAT GO:0014823| response to activity TPH2;CAT GO:0043627| response to estrogen stimulus TPH2;PPARG GO:0045600| positive regulation of fat cell differentiation TPH1;PPARG;HTR2A GO:0051384| response to glucocorticoid stimulus PTGS2;TPH2 19936:[DB14011 DB03233] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03233|Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways GO:0046686| response to cadmium ion DTYMK;CAT GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;DTYMK;TRPV1 GO:0043627| response to estrogen stimulus PPARG;DTYMK GO:0015949| nucleobase-containing small molecule interconversion DTYMK;GSR GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1;DTYMK GO:0045445| myoblast differentiation DTYMK;HMGCR 19937:[DB14011 DB08806] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08806|Roxatidine acetate HRH2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;GPR12;CNR1;HRH2;OPRM1;CNR2;OPRD1;PPARG;GPR18 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HRH2;CNR1;OPRD1;CNR2;OPRM1 GO:0008542| visual learning HMGCR;HRH2 GO:0048565| digestive tract development CYP1A1;HRH2 GO:0006955| immune response OPRD1;CNR2;HRH2 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HRH2;HTR2A;CNR1;GPR12 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;HRH2 GO:0007613| memory CHRNA7;HRH2;CNR1;HTR2A;PTGS2 19938:[DB14011 DB12498] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG;CXCR4 GO:0001666| response to hypoxia CHRNA7;CAT;CXCR4;CYP1A1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;CXCR4 GO:0006915| apoptotic process VDAC1;CXCR4;GPX1 GO:0000187| activation of MAPK activity PLA2G1B;CXCR4;SOD1;CHRNA7 GO:0009615| response to virus CXCR4;CYP1A1 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CXCR4;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0071345| cellular response to cytokine stimulus CXCR4;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;CXCR4;TRPV1;TRPV4 GO:0016032| viral reproduction HTR2A;CXCR4;VDAC1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;IDO1;CXCR4 19939:[DB14011 DB07388] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07388|ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2;NOS3 common genes common pathways GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0009408| response to heat TRPV2;SOD1;TRPV3;NOS3;TRPV1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045776| negative regulation of blood pressure NOS3;NOS2;CNR1 GO:0001525| angiogenesis NOS3;CYP1B1;PTGS2 GO:1902042| NOS3;GPX1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;NOS3;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1;NOS3 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3;NOS2 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS3;GSR;NOS2 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;NOS3;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;NOS2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0042311| vasodilation GPX1;NOS3 GO:0030324| lung development CYP1A2;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0032496| response to lipopolysaccharide NOS2;CYP1A1;IDO1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0007623| circadian rhythm NOS2;AANAT GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0045766| positive regulation of angiogenesis CYP1B1;NOS3;CHRNA7 19940:[DB14011 DB00827] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes CYP1A2 common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1A1;CYP2C9;CRYZ;ALOX5;GPX1;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1A1;CYP2C9;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;SLC22A6;TRPA1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0098656| VDAC1;SLC22A6 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 19941:[DB14011 DB11967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes CYP1A2;CYP2C19 common pathways GO:0010468| regulation of gene expression CYP1A2 GO:0002446| neutrophil mediated immunity IL6;PLA2G1B GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;UGT1A1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0032966| negative regulation of collagen biosynthetic process IL6;PPARG GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;UGT1A1;CYP2D6;CYP2C19 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;IL1B;TNF;PTGS2;OPRM1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0045766| positive regulation of angiogenesis IL1B;CYP1B1;CHRNA7 GO:0006915| apoptotic process GPX1;IL1B;VDAC1 GO:0000187| activation of MAPK activity IL1B;PLA2G1B;TNF;CHRNA7;MAP2K2;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;MAP2K2;TNF;ALOX15;TRPV4 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TNF;TRPA1;PPARG;CYP1A1;UGT1A1 GO:0043407| negative regulation of MAP kinase activity SMPD1;IL1B;HMGCR GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0010628| positive regulation of gene expression TNF;TRPV4;IL6;IL1B GO:0001660| fever generation IL1B;TRPV1 GO:0046330| positive regulation of JNK cascade IL1B;TRPV4;TNF GO:0071639| positive regulation of monocyte chemotactic protein-1 production IL1B;TRPV4 GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1;IDO1;IL1B;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;TNF GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation PPARG;UGT1A1;ACAT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;PPARG;TRPV1;TRPV4 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;IL6 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0032259| methylation CYP1A2 GO:0009615| response to virus TNF;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;IL6;PLA2G1B;TNF;PPARG GO:0008284| positive regulation of cell proliferation IL6;IL1B;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0046427| positive regulation of JAK-STAT cascade IL6;CYP1B1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF;IL1B;IL6;MAP2K2 GO:0071407| cellular response to organic cyclic compound IL1B;CYP1B1;CYP1A1;TNF GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0050830| defense response to Gram-positive bacterium TNF;IL6;PLA2G1B GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;UGT1A1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;TNF;IL6 GO:0050796| regulation of insulin secretion CNR1;TNF;IL1B GO:0007566| embryo implantation PTGS2;SOD1;IL1B GO:0051384| response to glucocorticoid stimulus IL6;UGT1A1;TNF;PTGS2 GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;IL1B;ALOX15 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;IL6;TNF GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;IL1B;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG;CYP1A1;TRPA1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0006919| activation of caspase activity TNF;PPARG GO:0045333| cellular respiration CYP1A2 GO:0008285| negative regulation of cell proliferation IL6;CYP1B1;IL1B;PPARG;OPRM1;PTGS2 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;UGT1A1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;IL6 GO:0051781| positive regulation of cell division CAT;IL1B GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0001889| liver development ACAT1;UGT1A1;CYP1A1 GO:0031622| positive regulation of fever generation PTGS2;CNR1;IL1B;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1;UGT1A1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;IL1B;CYP1B1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;UGT1A1;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAP3K1;IL1B GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0008152| metabolic process ACAT1;SMPD1;UGT1A1 GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IL6;IDO1;SMPD1;PPARG;TNF;PTGS2;SOD1;CNR1 GO:0001934| positive regulation of protein phosphorylation TNF;IL1B;CHRNA7 GO:0010629| negative regulation of gene expression MAP2K2;OPRD1;TNF GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:2000778| positive regulation of interleukin-6 secretion IL1B;TRPV4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL6 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;IL1B;PPARG;TNF GO:0006955| immune response TNF;IL6;IL1B;OPRD1;CNR2 GO:0006954| inflammatory response TNF;ALOX15;IL1B;IDO1;TRPV1;IL6;CNR2;PTGS2;PTGS1;ALOX5 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;PLA2G1B;IL6;IL1B;CAT 19942:[DB14011 DB01632] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0008152| metabolic process SMPD1;UCKL1;ACAT1 GO:0007595| lactation SLC29A1;APRT GO:0051289| protein homotetramerization TRPM8;HPRT1;TRPV1;TRPA1;CRYZ;CAT GO:0016032| viral reproduction HTR2A;VDAC1;UCKL1 GO:0032869| cellular response to insulin stimulus PPARG;APRT;PLA2G1B GO:0001975| response to amphetamine SOD1;CNR2;HPRT1 GO:0043312| neutrophil degranulation APRT;ALOX5;CAT GO:0007626| locomotory behavior HPRT1;SOD1;OPRM1 19943:[DB14011 DB04071] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04071|Cpad ADH1C common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;ADH1C;CAT;ALOX5;GPX1;PTGS1;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1 19944:[DB14011 DB00562] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways GO:0006811| ion transport TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;SLC12A3;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SLC12A3;CACNA1H GO:1902476| GLRB;GLRA1;SLC12A3;GLRA3 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0006810| transport TRPV2;SLC12A3;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0055085| transmembrane transport TRPV2;SLC12A3;CACNA1H;TRPV3;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0001666| response to hypoxia CA9;CHRNA7;CAT;CYP1A1 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1;CA2 GO:0001822| kidney development CAT;CA2 GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT;CA9 19945:[DB14011 DB02821] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02821|Canaline OAT common genes common pathways GO:0007601| visual perception CYP1B1;GLRB;OAT;CRYZ;GLRA1 19946:[DB14011 DB01370] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0006811| ion transport TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;ATP1A1;GLRA3;CACNA1H;TRPV3;TF GO:0008344| adult locomotory behavior OPRD1;APP GO:0001895| retina homeostasis ALB;TF;SOD1 GO:0061844| PLA2G1B;APP GO:0032930| positive regulation of superoxide anion generation SOD1;APP GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;APP;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;ATP1A1;PTGS2 GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2;APP GO:0007204| elevation of cytosolic calcium ion concentration APP;TRPV4;TRPV1;OPRM1;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRM1;OPRD1 GO:1900273| CHRNA7;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;APP;GLRA1;OPRM1;OPRD1;GLRA3;HTR2A GO:0010629| negative regulation of gene expression APP;OPRD1 GO:0071320| cellular response to cAMP APP;AANAT GO:1902004| CHRNA7;APP GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;APP GO:0008542| visual learning HMGCR;APP GO:0006879| cellular iron ion homeostasis TF;SOD1;ABCG2 GO:0001774| microglial cell activation TRPV1;APP GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;APP;IDO1;CYP1B1;TRPV1 GO:1990090| TRPV1;APP GO:0007399| nervous system development SMPD1;APP;GLRB GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;ATP1A1;GLRA3;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4;APP GO:0086002| ATP1A1;CACNA1G GO:0000187| activation of MAPK activity PLA2G1B;APP;CHRNA7;SOD1 GO:0006915| apoptotic process GPX1;APP;VDAC1 GO:0010628| positive regulation of gene expression APP;TRPV4 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0051262| protein tetramerization APP;CAT;HMGCR GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG;APP GO:0098815| CHRNA7;APP GO:0010468| regulation of gene expression APP;CYP1A2 GO:0051260| protein homooligomerization GLRA1;APP;GLRA3;ACAT1 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TRPV1;OPRM1;PTGS2 GO:0098869| ALB;GSR;PTGS2;GPX1;PTGS1;CAT GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2;APP GO:0042493| response to drug SOD1;HTR2A;ATP1A1;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0050808| synapse organization CHRNA7;APP GO:0019731| antibacterial humoral response APP;PLA2G1B GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0008203| cholesterol metabolic process CAT;HMGCR;APP GO:0007612| learning APP;VDAC1;PTGS2 GO:0007611| learning or memory CNR1;CHRNA7;APP GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:1905906| CHRNA7;APP GO:0002576| platelet degranulation SOD1;TF;APP;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;APP GO:0007626| locomotory behavior APP;OPRM1;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;ALB GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;APP GO:0045087| innate immune response APP;PPARG GO:0007155| cell adhesion APP;CYP1B1 GO:0010288| response to lead ion APP;CAT 19947:[DB14011 DB03731] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03731|S-2-(Boronoethyl)-L-Cysteine ARG1;ARG2 common genes common pathways GO:0046686| response to cadmium ion CAT;ARG1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ARG1 GO:0042130| negative regulation of T cell proliferation ARG1;IDO1 GO:0001657| ureteric bud development ARG2;CAT GO:0007568| aging CYP1A1;CAT;ARG1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD GO:0009611| response to wounding GPX1;ARG1;CYP1A1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;ARG2;CHRNA7 GO:0002376| immune system process ARG1;ARG2;IDO1 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT;ARG1 GO:0033189| response to vitamin A CYP1A1;PPARG;ARG1;CAT GO:0010042| response to manganese ion ARG1;PTGS2 GO:0030324| lung development ARG1;CYP1A2 GO:0032496| response to lipopolysaccharide ARG1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E ARG1;CAT GO:0045087| innate immune response PPARG;ARG1;ARG2 GO:0043312| neutrophil degranulation ALOX5;ARG1;CAT GO:0070207| protein homotrimerization ARG1;TRPM8 GO:0006809| nitric oxide biosynthetic process ARG2;CYP1B1 GO:0010269| response to selenium ion GPX1;ARG1 GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;ARG1 GO:0010043| response to zinc ion AANAT;ARG1 GO:0043434| response to peptide hormone stimulus TRPV1;ARG1 GO:0007565| female pregnancy ARG1;IDO1 GO:0009635| response to herbicide ARG1;CYP1A1 GO:0001889| liver development ARG1;ACAT1;CYP1A1 GO:0048678| response to axon injury ARG1;SOD1 19948:[DB14011 DB11294] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11294|Coccidioides immitis spherule HLA-A;HLA-A;HLA-B common genes common pathways GO:0045087| innate immune response PPARG;HLA-B GO:0002376| immune system process IDO1;HLA-A;HLA-B GO:0016032| viral reproduction HTR2A;HLA-B;HLA-A;VDAC1 GO:0006955| immune response HLA-A;CNR2;OPRD1;HLA-B 19949:[DB14011 DB08800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08800|Chloropyramine HRH1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;HRH1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HRH1;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ALOX5;PTGS1;CNR2;PTGS2;HRH1 GO:0008542| visual learning HMGCR;HRH1 GO:0007613| memory CHRNA7;PTGS2;HRH1;CNR1;HTR2A GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;HRH1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 19950:[DB14011 DB07239] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;DPP4;CYP1A1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 19951:[DB14011 DB08384] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;PDE10A GO:0008152| metabolic process ACAT1;PDE10A;SMPD1 GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;PDE10A;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I 19952:[DB14011 DB05398] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05398|C31G CD9 common genes common pathways GO:0002576| platelet degranulation SOD1;CD9 GO:0007155| cell adhesion CD9;CYP1B1 GO:0071404| cellular response to low-density lipoprotein particle stimulus CD9;PPARG GO:0007420| brain development CD9;ACAT1 GO:0008285| negative regulation of cell proliferation CD9;CYP1B1;PPARG;OPRM1;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;CD9 19953:[DB14011 DB00054] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:0043277| apoptotic cell clearance ALOX15;ITGB3 GO:0002376| immune system process C1QC;C1S;C1QA;C1R;C1QB;IDO1;FCGR1A;FCGR2A GO:0042060| wound healing ALOX15;ITGB3;OPRM1 GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0002576| platelet degranulation ITGB3;ITGA2B;SOD1 GO:0007155| cell adhesion ITGA2B;VTN;ITGB3;CYP1B1 GO:0045087| innate immune response PPARG;C1R;C1QB;FCGR1A;C1S;C1QC;C1QA GO:0043312| neutrophil degranulation ALOX5;CAT;FCGR2A;FCGR3B GO:0010745| negative regulation of macrophage derived foam cell differentiation ITGB3;PPARG GO:0046718| entry of virus into host cell HTR2A;ITGB3 GO:0060055| angiogenesis involved in wound healing ITGB3;GPX1 GO:0010811| positive regulation of cell-substrate adhesion VTN;ALOX15 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;FCGR2C;FCGR1A;CACNA1I;PLA2G1B;FCGR2B;PPARG;GPR18;SMPD1 GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0001934| positive regulation of protein phosphorylation CHRNA7;ITGB3 GO:0006954| inflammatory response PTGS2;CNR2;PTGS1;ALOX5;FCGR2B;TRPV1;IDO1;ALOX15 GO:0016032| viral reproduction FCGR2B;VDAC1;ITGB3;HTR2A GO:0006955| immune response FCGR1A;C1R;FCGR2B;FCGR3B;FCGR3A;OPRD1;FCGR2C;VTN;CNR2;C1QC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VTN;HTR2A;ITGB3 19954:[DB14011 DB01277] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;INSR GO:0045893| positive regulation of transcription, DNA-dependent INSR;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;INSR GO:0007612| learning PTGS2;VDAC1;INSR GO:0032526| response to retinoic acid PPARG;IGF2R GO:0008284| positive regulation of cell proliferation INSR;CHRNA7;HTR1A;HTR2A;PTGS2;IGF1R;HMGCR GO:0043066| negative regulation of apoptotic process IGF1R;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0043312| neutrophil degranulation CAT;ALOX5;IGF2R GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;INSR GO:0006915| apoptotic process VDAC1;IGFBP3;GPX1 GO:0007283| spermatogenesis SOD1;CNR1;IGF2R GO:0051262| protein tetramerization CAT;HMGCR;IGF1R GO:0007186| G-protein coupled receptor signaling pathway INSR;IGF2R;GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0042593| glucose homeostasis CNR1;PPARG;INSR;TRPV4 GO:0031100| organ regeneration IGF2R;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;INSR GO:0001934| positive regulation of protein phosphorylation CHRNA7;INSR GO:0006955| immune response OPRD1;CNR2;IGF1R GO:0045821| positive regulation of glycolysis HTR2A;INSR GO:0001889| liver development ACAT1;CYP1A1;IGF2R GO:0043065| positive regulation of apoptotic process IGFBP3;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;IGF2R;SMPD1 GO:0035556| intracellular signal transduction PLA2G1B;INSR GO:0009791| post-embryonic development CYP1A2;IGF2R GO:0045740| positive regulation of DNA replication INSR;PLA2G1B;IGF1R GO:0008285| negative regulation of cell proliferation IGFBP3;PTGS2;OPRM1;CYP1B1;PPARG GO:0032869| cellular response to insulin stimulus PPARG;INSR;PLA2G1B GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2;INSR GO:0001649| osteoblast differentiation CAT;IGFBP3 GO:0014065| phosphatidylinositol 3-kinase cascade IGF1R;HTR2A GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IGFBP3 GO:0007165| signal transduction CHRNA7;OPRM1;IGF1R;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;IGF2R 19955:[DB14011 DB00461] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes CYP1A2;PTGS1;PTGS2 common pathways GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0032094| response to food CYP1A1;OPRM1;MPO GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A1;CYP2C9;CRYZ;ALOX5;MPO;GPX1;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1;MPO GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0009612| response to mechanical stimulus PPARG;TRPV4;MPO GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;MPO GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0032259| methylation CYP1A2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0043312| neutrophil degranulation MPO;ALOX5;CAT GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0042744| hydrogen peroxide catabolic process GPX1;MPO;CAT GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1A1;CYP2C9;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0010468| regulation of gene expression CYP1A2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging CAT;MPO;HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0006979| response to oxidative stress CAT;PTGS1;MPO;GPX1;SOD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| GSR;PTGS1;GPX1;CAT;PTGS2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0019430| removal of superoxide radicals MPO;SOD1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2;TRPV1;TRPA1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:1990776| PTGS2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6 GO:0045333| cellular respiration CYP1A2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 19956:[DB14011 DB02746] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes PPARG common pathways GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0071456| cellular response to hypoxia SLC29A1;PPARD;OPRD1;PTGS2 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0015909| long-chain fatty acid transport PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PPARD;CAT GO:0046697| decidualization PTGS2;PPARD GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TRPV1 GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;SLCO2B1;CACNA1G;ABCC1;TRPA1 GO:0006915| apoptotic process VDAC1;PPARD;GPX1 GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CYP1A1;PPARA;CAT;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;PPARD GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT;PPARA GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2;PPARD GO:0031000| response to caffeine PPARG GO:0015758| glucose transport PPARD;PLA2G1B GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0008203| cholesterol metabolic process RXRA;CAT;HMGCR;PPARD GO:0042060| wound healing ALOX15;PPARD;OPRM1;PPARA GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PPARD GO:0030308| negative regulation of cell growth ESR2;PPARG;PPARD GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0032526| response to retinoic acid PPARG;RXRA GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRB;RXRA;PGR;PLA2G1B;ESR2;RXRG;ESR1;PPARA GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;PPARD;CHRNA7 GO:0071300| cellular response to retinoic acid PPARG GO:0043066| negative regulation of apoptotic process GPX1;CAT;PPARD;HMGCR;PTGS2;SOD1 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;ESR2;PPARG;RXRA;PPARD;PPARA;ESR1 GO:0045087| innate immune response PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0006355| regulation of transcription, DNA-dependent PGR;ESR2;RXRG;PPARG;RXRB;RXRA;PPARD;ESR1;PPARA GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PPARA;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent PPARD;PPARA;ESR1;ESR2;RXRA;PPARG GO:0030224| monocyte differentiation PPARG GO:0050728| negative regulation of inflammatory response CNR2;PPARD;PPARA GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;RXRG;PGR;PPARG;RXRB;RXRA;ESR1;PPARA;PPARD GO:0033189| response to vitamin A CYP1A1;PPARG;PPARD;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;RXRA;PPARA;CNR1;HMGCR GO:0007566| embryo implantation PTGS2;PPARD;SOD1;RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG;RXRA GO:0060694| regulation of cholesterol transporter activity PPARG GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;ESR1;HTR2A GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0007165| signal transduction PGR;PLA2G1B;CACNA1I;ESR2;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;ESR1 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;SLCO2B1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0008283| cell proliferation CYP1A1;PPARD;HTR1A;GPX1 GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT;PPARA GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;PPARD GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARD;RXRA;PPARG GO:0060612| adipose tissue development ACAT1;PPARD GO:0019395| fatty acid oxidation PPARG;PPARD GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0014823| response to activity CAT;PPARD GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;PPARD;ESR1 GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway RXRB;RXRA;PPARG;ESR2;RXRG;PGR;ESR1;PPARA;PPARD GO:0006351| transcription, DNA-dependent PPARD;PPARA;ESR1;PGR;RXRG;ESR2;RXRA;RXRB;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0007507| heart development PPARG;RXRA;PPARD;PPARA GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;CYP2C9;PPARG;GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;PPARA;PTGS2;CYP1A2;HMGCR;PPARD GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0010629| negative regulation of gene expression OPRD1;ESR1;PGR GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0051289| protein homotetramerization CAT;RXRG;TRPM8;TRPV1;TRPA1;RXRA;CRYZ GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0016032| viral reproduction HTR2A;RXRA;VDAC1 GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG 19957:[DB14011 DB02175] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02175|Malonic acid panD;SRC;SNRPA common genes common pathways GO:0008283| cell proliferation HTR1A;GPX1;SRC;CYP1A1 GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;SRC;CHRNA7 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption GPR55;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;SRC;SOD1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2;SRC GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;SRC;CHRNA7;TRPV4;ALOX15 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0002376| immune system process SRC;IDO1 GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;SRC;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0045087| innate immune response PPARG;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0009615| response to virus CYP1A1;SRC GO:0009612| response to mechanical stimulus TRPV4;PPARG;SRC GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;SRC;CAT 19958:[DB14011 DB02118] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02118|CP-271485 MMP12 common genes common pathways GO:0042060| wound healing MMP12;OPRM1;ALOX15 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;PPARG;PLA2G1B GO:0010628| positive regulation of gene expression MMP12;TRPV4 19959:[DB14011 DB00892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;BCHE GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0086016| CACNA1G;SCN10A GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;SCN10A;TRPA1;TRPV2;TRPV3;CACNA1H GO:0007600| sensory perception TRPV2;OPRM1;SCN10A GO:0086010| CACNA1H;CACNA1I;CACNA1G;SCN10A GO:0019233| sensory perception of pain TRPV1;SCN10A;TRPA1;OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1 GO:0035725| sodium ion transmembrane transport CACNA1H;CACNA1G;SCN10A;CACNA1I GO:0019228| regulation of action potential in neuron CACNA1H;SCN10A;CACNA1G;CACNA1I GO:0002027| regulation of heart rate CACNA1G;SCN10A GO:0006811| ion transport CACNA1G;SCN10A;GLRA1;TRPA1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPM8;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN10A GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCHE;PPARG;CYP1B1 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0034765| regulation of ion transmembrane transport SCN10A;CACNA1G;CACNA1I;CACNA1H 19960:[DB14011 DB02558] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways GO:0001822| kidney development CAT;MME GO:0043312| neutrophil degranulation CAT;ALOX5;MME GO:0071345| cellular response to cytokine stimulus TRPV1;MME GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;PTGS2;CNR2;OPRM1;MME;CNR1;HTR2A 19961:[DB14011 DB04591] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04591|N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINE F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0009611| response to wounding F2;CYP1A1;GPX1 19962:[DB14011 DB08530] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0001666| response to hypoxia DPP4;CYP1A1;CAT;CHRNA7 19963:[DB14011 DB13925] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways GO:0007584| response to nutrient HMGCR;CNR1;SSTR2;PPARG GO:0008285| negative regulation of cell proliferation SSTR2;PPARG;CYP1B1;OPRM1;PTGS2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway SSTR2;OPRM1;OPRD1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CACNA1I;PLA2G1B;SMPD1;SSTR2;GPR18;PPARG GO:0007218| neuropeptide signaling pathway GLRA1;SSTR2;GLRB;GLRA3;OPRD1;OPRM1 GO:0042594| response to starvation ACAT1;SSTR2;PPARG GO:0007283| spermatogenesis SOD1;CNR1;SSTR2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;OPRM1;CNR2;SSTR2 GO:0007186| G-protein coupled receptor signaling pathway SSTR2;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 19964:[DB14011 DB14060] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14060|NS-398 PTGS2 common genes PTGS2 common pathways GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning PTGS2;VDAC1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;CYP1A1;IDO1 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;GPX1;ALOX5;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0098869| GSR;PTGS2;PTGS1;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0007568| aging CYP1A1;CAT;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:1902219| PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;TRPA1;TRPV1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;IDO1 GO:0010942| positive regulation of cell death PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0033280| response to vitamin D PTGS2 19965:[DB14011 DB07468] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07468|(3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways GO:0007605| sensory perception of sound MYH14;GPX1;SOD1 GO:0019228| regulation of action potential in neuron MYH14;CACNA1I;CACNA1G;CACNA1H 19966:[DB14011 DB01180] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01180|Rescinnamine ACE common genes common pathways GO:0001822| kidney development ACE;CAT GO:0007283| spermatogenesis ACE;SOD1;CNR1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0008217| regulation of blood pressure PPARG;PTGS1;ACE;PTGS2;SOD1 GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0060047| heart contraction ACE;GPX1;SOD1 19967:[DB14011 DB00310] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00310|Chlorthalidone SLC12A1 common genes common pathways GO:0006810| transport ABCC1;ABCG2;TRPV1;CACNA1I;SLC12A1;TRPV2 GO:0055085| transmembrane transport TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;ABCC1;CACNA1G;SLC12A1;TRPV2;TRPV3;CACNA1H GO:0034220| ion transmembrane transport TRPV1;GLRB;TRPA1;GLRA1;SLC12A1;CHRNA7;GLRA3 GO:1902476| GLRA1;GLRB;GLRA3;SLC12A1 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;GLRA3;CACNA1H;TRPV3;SLC12A1;CHRNA7;TRPV2 19968:[DB14011 DB02170] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02170|1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One CSNK2A1 common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;CSNK2A1;OPRD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2;GPX1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG GO:0006915| apoptotic process VDAC1;CSNK2A1;GPX1 GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;CSNK2A1;HMGCR;HTR1A;HTR2A 19969:[DB14011 DB00913] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00913|Anileridine OPRM1 common genes OPRM1 common pathways GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0042220| response to cocaine CNR1;OPRM1;SMPD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;TRPV1;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0042060| wound healing ALOX15;OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;IDO1;CYP1A1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0070848| response to growth factor stimulus OPRM1 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;OPRD1;OPRM1;GLRA3 GO:0007626| locomotory behavior SOD1;OPRM1 GO:0032094| response to food OPRM1;CYP1A1 GO:0043278| response to morphine OPRM1;CNR1 GO:0032100| positive regulation of appetite OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1 GO:0071315| cellular response to morphine OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007165| signal transduction GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0044849| OPRM1 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;TRPV3;CACNA1H;OPRM1;TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0042755| eating behavior OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1 GO:0045471| response to ethanol HMGCR;OPRM1;SOD1;CNR1;CAT GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;OPRD1;OPRM1;GLRA3;HTR2A GO:0007600| sensory perception TRPV2;OPRM1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 19970:[DB14011 DB08848] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08848|Guvacine SLC6A13;SLC6A1;SLC6A11;SLC6A12 common genes common pathways GO:0007420| brain development SLC6A11;ACAT1 GO:0032229| negative regulation of synaptic transmission, GABAergic CNR2;SLC6A1 GO:0009636| response to toxin SLC6A1;GPX1;CAT;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;SLC6A1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0051592| response to calcium ion SLC6A1;AANAT GO:0007268| synaptic transmission SLC6A1;GLRA3;HTR2A;OPRM1;OPRD1;GLRB;VDAC1;GLRA1;CACNA1G GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;SLC6A1;TRPV2;SLC6A12 GO:0032355| response to estradiol stimulus CAT;SLC6A1;PTGS2;CYP1A2 GO:0051260| protein homooligomerization SLC6A1;GLRA3;ACAT1;GLRA1 GO:0055085| transmembrane transport TRPV2;SLC6A12;SLC6A13;CACNA1H;TRPV3;SLC6A1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;SLC6A11;CACNA1G;ABCC1;TRPA1 GO:0042220| response to cocaine CNR1;SLC6A1;OPRM1;SMPD1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SLC6A1;SOD1;CYP1A2;PTGS2 GO:0007612| learning VDAC1;SLC6A1;PTGS2 GO:0010288| response to lead ion CAT;SLC6A1 GO:0042493| response to drug ABCG2;SLC6A11;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0010243| response to organic nitrogen SLC6A1;PTGS2;TRPV1 19971:[DB14011 DB04854] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04854|Febuxostat XDH common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;XDH;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2;XDH GO:0006919| activation of caspase activity XDH;PPARG GO:0007595| lactation XDH;SLC29A1 GO:0006195| purine nucleotide catabolic process GPX1;XDH GO:0010629| negative regulation of gene expression XDH;OPRD1 19972:[DB14011 DB00975] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ABCC4;ACAT1;AANAT;CYP1A2;PTGS2 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;SLCO2B1;TRPM8;CACNA1H;TRPV3;SLCO1B3;SLCO1B1;GLRA3;TRPV2;CHRNA7 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0001890| placenta development ADA;SOD1;PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0007165| signal transduction GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;PDE4A;OPRD1;PDE10A;CHRNA7;RCAN1;PPARG;GPR18;PDE5A;SMPD1;PLA2G1B;CACNA1I GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;ALOX15;IDO1;ORM1 GO:0035725| sodium ion transmembrane transport ABCB11;CACNA1H;CACNA1I;CACNA1G GO:0001889| liver development ADA;ACAT1;CYP1A1 GO:0008152| metabolic process PDE5A;SMPD1;PDE10A;ACAT1 GO:0042542| response to hydrogen peroxide GPX1;ADA;CAT;SOD1;TRPA1 GO:0055085| transmembrane transport TRPV1;VDAC1;TRPV4;ABCB1;CACNA1I;ABCG2;SLCO2B1;TRPM8;ABCC5;CACNA1G;ABCC1;TRPA1;TRPV2;ABCC4;CACNA1H;TRPV3;SLCO1B3;SLCO1B1;ABCB11 GO:0001666| response to hypoxia ADA;CHRNA7;CAT;CYP1A1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2;ABCC4 GO:0042130| negative regulation of T cell proliferation PDE5A;IDO1 GO:0043406| positive regulation of MAP kinase activity PDE5A;HTR2A GO:0007186| G-protein coupled receptor signaling pathway PDE10A;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;PDE4A;OPRD1;PPARG;GPR18 GO:0007568| aging CYP1A1;CAT;ADA;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2 GO:0006810| transport ABCB11;TRPV2;ABCC1;CACNA1I;ABCB1;TRPV1;ABCC5;ABCG2 GO:0032720| negative regulation of tumor necrosis factor production GPR18;ORM1;CHRNA7 GO:0099133| ABCC4;ABCC1;ABCC5 GO:0042493| response to drug ABCC4;ADA;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCB1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0006355| regulation of transcription, DNA-dependent PPARG;RCAN1 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1A1;CYP2C9;CRYZ;ALOX5;PTGS1;GPX1;ABCC4;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;ABCC4 GO:0010243| response to organic nitrogen TRPV1;ABCC4;PTGS2 GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0043278| response to morphine OPRM1;CNR1;ADA GO:0033197| response to vitamin E ADA;CAT GO:0030324| lung development ADA;CYP1A2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;ADA GO:0002576| platelet degranulation ORM1;SOD1;ABCC4 GO:0043312| neutrophil degranulation ORM1;CAT;ALOX5 GO:0007155| cell adhesion CYP1B1;ADA 19973:[DB14011 DB02512] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways GO:0007015| actin filament organization TRPV4;PLA2G1B;ALDOA GO:0043312| neutrophil degranulation ALOX5;CAT;ALDOA GO:0002576| platelet degranulation ALDOA;SOD1 GO:0046716| muscle cell homeostasis SOD1;ALDOA GO:0051289| protein homotetramerization TRPM8;TRPV1;TRPA1;CRYZ;ALDOA;CAT 19974:[DB14011 DB12589] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12589|Dacetuzumab CD40 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;CD40;PLA2G1B GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CD40 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;IDO1;CD40;CYP1A1 GO:0002376| immune system process IDO1;CD40 GO:0006874| cellular calcium ion homeostasis CD40;TRPV4;TRPM8;HTR2A;GPR12;CHRNA7 GO:0032735| positive regulation of interleukin-12 production CD40;IDO1 GO:0043406| positive regulation of MAP kinase activity HTR2A;CD40 GO:0071356| cellular response to tumor necrosis factor CD40;TRPV1 GO:0045766| positive regulation of angiogenesis CD40;CYP1B1;CHRNA7 GO:0071260| cellular response to mechanical stimulus PTGS2;CD40 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CD40;CAT GO:0006954| inflammatory response CD40;IDO1;ALOX15;TRPV1;PTGS2;CNR2;ALOX5;PTGS1 GO:0006955| immune response CD40;CNR2;OPRD1 GO:0031667| response to nutrient levels CD40;SOD1 GO:0001934| positive regulation of protein phosphorylation CD40;CHRNA7 19975:[DB14011 DB07106] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways GO:0032259| methylation CYP1A2;HNMT GO:0007420| brain development ACAT1;HNMT 19976:[DB14011 DB04961] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04961|Troxacitabine DCK common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;DCK 19977:[DB14011 DB09097] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways GO:0006874| cellular calcium ion homeostasis TRPM8;DRD2;TRPV4;GPR12;HTR2A;CHRNA7;DRD5 GO:0006936| muscle contraction GLRA1;CACNA1H;DRD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;DRD2;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;DRD5;DRD1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;DRD2;TRPV1;HTR2A GO:0001666| response to hypoxia CAT;CHRNA7;DRD2;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;DRD1 GO:0009416| response to light stimulus DRD2;AANAT GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger DRD1;OPRM1;CNR2;OPRD1;CNR1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD2;GPR18;DRD1;GPR55 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;DRD2;ALOX15 GO:0042220| response to cocaine OPRM1;CNR1;DRD5;DRD1;SMPD1;DRD2 GO:0007626| locomotory behavior SOD1;OPRM1;DRD1;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;PPARG GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway DRD5;DRD1;OPRM1 GO:0042311| vasodilation DRD1;GPX1 GO:0007628| adult walking behavior GLRB;DRD2;GLRA1;DRD1 GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0007612| learning VDAC1;DRD1;DRD5;PTGS2 GO:0042060| wound healing OPRM1;DRD5;ALOX15 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;DRD2;GLRB;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0043278| response to morphine OPRM1;CNR1;DRD2 GO:0042493| response to drug CAT;DRD1;CYP1A2;PTGS2;SOD1;HTR2A;DRD2;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:1900273| DRD2;CHRNA7 GO:0050482| arachidonic acid secretion DRD2;PLA2G1B GO:0007165| signal transduction DRD5;DRD1;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;DRD2;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0072593| reactive oxygen species metabolic process DRD5;SOD1 GO:0001975| response to amphetamine DRD2;CNR2;SOD1;DRD5;DRD1 GO:0007613| memory PTGS2;HTR2A;CNR1;DRD1;CHRNA7 GO:0042053| regulation of dopamine metabolic process DRD1;HTR1A GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0001662| behavioral fear response DRD1;HTR1A;VDAC1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;DRD2;OPRM1;PTGS2 GO:0009636| response to toxin CYP1B1;DRD2;CYP1A1;GPX1;CAT GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0014854| response to inactivity DRD2;CAT GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0001659| temperature homeostasis GPX1;DRD1;HTR2A;DRD2;TRPV1 GO:0048148| behavioral response to cocaine HTR2A;DRD1;DRD2 GO:0035556| intracellular signal transduction PLA2G1B;DRD2 GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0045776| negative regulation of blood pressure DRD2;DRD5;CNR1 GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT;DRD2 GO:0048678| response to axon injury SOD1;DRD2 GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;DRD1;CACNA1H GO:0019226| transmission of nerve impulse SOD1;DRD5;DRD1 GO:0001964| startle response DRD2;GLRB;GLRA1 GO:0008542| visual learning DRD2;DRD1;HMGCR GO:0007268| synaptic transmission CACNA1G;GLRA1;GLRB;VDAC1;OPRM1;OPRD1;HTR2A;GLRA3;DRD5 GO:0048149| behavioral response to ethanol DRD2;OPRM1 19978:[DB14011 DB08629] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08629|N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;ATP5B;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;PTGS1;NAAA;GPX1 GO:0001525| angiogenesis ATP5B;CYP1B1;PTGS2 GO:0006811| ion transport VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1G;ATP5B;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3 GO:0001649| osteoblast differentiation ATP5B;CAT 19979:[DB14011 DB04886] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04886|Calanolide A CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;PTGS1;NAAA;GPX1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0002933| CYP3A7;CYP3A4;CYP3A5;CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 19980:[DB14011 DB06936] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06936|N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 19981:[DB14011 DB05075] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0046330| positive regulation of JNK cascade FLT4;TRPV4 GO:0042127| regulation of cell proliferation CSK;PTGS2;PTGS1 GO:0045087| innate immune response CSK;PPARG GO:0043066| negative regulation of apoptotic process FLT4;KDR;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation FLT4;KDR;PTGS2;FLT1;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0048514| blood vessel morphogenesis FLT1;CYP1B1;FLT4 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;FLT1;CAT GO:0002376| immune system process IDO1;CSK GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7;FLT1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;FLT4;ALOX15;TRPV4;KDR GO:0043406| positive regulation of MAP kinase activity HTR2A;FLT1;CSK GO:0001525| angiogenesis PTGS2;FLT1;CYP1B1;KDR;FLT4 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1;FLT4 GO:0001934| positive regulation of protein phosphorylation FLT4;KDR;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0016032| viral reproduction KDR;VDAC1;HTR2A GO:0007420| brain development CSK;ACAT1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1;CSK 19982:[DB14011 DB04736] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways GO:0002376| immune system process PGLYRP3;IDO1 GO:0045087| innate immune response PPARG;PGLYRP3 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;PGLYRP3 GO:0061844| PGLYRP3;PLA2G1B 19983:[DB14011 DB05364] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05364|ROX-888 CCL3 common genes common pathways GO:0010629| negative regulation of gene expression OPRD1;CCL3 GO:0006954| inflammatory response PTGS1;ALOX5;CCL3;CNR2;PTGS2;TRPV1;IDO1;ALOX15 GO:0006816| calcium ion transport TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;TRPV2;CCL3;CHRNA7;TRPV3;CACNA1H GO:0006955| immune response CNR2;OPRD1;CCL3 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;CCL3 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;CCL3;GPX1 GO:0090280| positive regulation of calcium ion import TRPV2;CCL3;TRPV3 GO:0050729| positive regulation of inflammatory response TRPV4;CCL3 GO:0001649| osteoblast differentiation CCL3;CAT GO:0007610| behavior CCL3;HTR1A;HTR2A GO:0030593| neutrophil chemotaxis PLA2G1B;CCL3 GO:0071407| cellular response to organic cyclic compound CCL3;CYP1B1;CYP1A1 GO:0051897| positive regulation of protein kinase B signaling cascade CCL3;GPX1 GO:0045671| negative regulation of osteoclast differentiation GPR55;CCL3 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CCL3;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0010628| positive regulation of gene expression CCL3;TRPV4 GO:0071356| cellular response to tumor necrosis factor CCL3;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CCL3 GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;CCL3;CHRNA7;TRPM8;TRPV4 19984:[DB14011 DB05095] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05095|Cimicoxib PTGS2;PTGS2 common genes PTGS2 common pathways GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;CAT;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;IDO1;CYP1A1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS2;CNR2;PTGS1;ALOX5 GO:0010942| positive regulation of cell death PTGS2 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:1990776| PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 19985:[DB14011 DB00278] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00278|Argatroban F2;CYP3A4;CYP3A5 common genes CYP3A5;CYP3A4 common pathways GO:0061844| F2;PLA2G1B GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP1A1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6 GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 19986:[DB14011 DB00067] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;AVPR1A GO:0045777| positive regulation of blood pressure AVPR2;CNR1;AVPR1A GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCG2 GO:0032870| cellular response to hormone stimulus CACNA1H;AVPR1A;AVPR1B;AVPR2;ABCC2 GO:0045907| positive regulation of vasoconstriction AVPR1B;AVPR2;PTGS2;HTR2A;AVPR1A GO:0051412| response to corticosterone stimulus AANAT;AVPR1A GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;AVPR1A;GPR55;HTR1A;AVPR2;CACNA1I;PLA2G1B;SMPD1;AVPR1B;GPR18;PPARG GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;AVPR1B;OPRM1;AVPR1A;HTR2A GO:0009408| response to heat ABCC2;TRPV1;TRPV2;SOD1;TRPV3 GO:0007565| female pregnancy IDO1;ABCC2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger AVPR2;CNR1 GO:0007202| activation of phospholipase C activity HTR2A;AVPR1A;GPR55;AVPR1B GO:0010628| positive regulation of gene expression AVPR2;TRPV4 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1;AVPR1A GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0055085| transmembrane transport CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;ABCC2;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0006979| response to oxidative stress ABCC2;SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway AVPR1A;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18;AVPR1B;AVPR2 GO:0006810| transport TRPV2;ABCC1;TRPV1;CACNA1I;ABCC2;ABCG2 GO:0051970| negative regulation of transmission of nerve impulse AVPR1A;GLRA1 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCC2;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0008284| positive regulation of cell proliferation AVPR2;CHRNA7;HTR2A;AVPR1A;HTR1A;HMGCR;PTGS2 GO:0034097| response to cytokine stimulus AVPR2;AANAT;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;IDO1;ABCC2;CYP1A1 GO:0014902| myotube differentiation GPX1;AVPR1A 19987:[DB14011 DB03216] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03216|(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine AHCY common genes common pathways GO:0032259| methylation AHCY;CYP1A2 GO:0001666| response to hypoxia CYP1A1;AHCY;CAT;CHRNA7 GO:0007584| response to nutrient HMGCR;CNR1;AHCY;PPARG 19988:[DB14011 DB05204] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05204|XL418 BTK common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;BTK;PTGS2 GO:0045087| innate immune response PPARG;BTK GO:0006355| regulation of transcription, DNA-dependent PPARG;BTK GO:0002376| immune system process BTK;IDO1 GO:0006915| apoptotic process VDAC1;GPX1;BTK GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;BTK;TRPA1;PPARG;CYP1A1 GO:0006351| transcription, DNA-dependent PPARG;BTK GO:0048469| cell maturation PPARG;BTK GO:0035556| intracellular signal transduction PLA2G1B;BTK GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;BTK;CAT 19989:[DB14011 DB02902] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG;SULT1E1 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;SULT1E1;CYP2C9;CYP1A1 GO:0008210| estrogen metabolic process CYP1B1;SULT1E1 19990:[DB14011 DB07116] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07116|1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0016032| viral reproduction HTR2A;UNG;VDAC1 19991:[DB14011 DB00789] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00789|Gadopentetic acid PGD common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;PGD;ALOX5;GPX1;PTGS1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6 19992:[DB14011 DB07646] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process DHODH;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0007565| female pregnancy DHODH;IDO1 GO:0007595| lactation SLC29A1;DHODH GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;DHODH;CYP1A2;PTGS2 GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1;DHODH;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;DHODH;CAT;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2 GO:0031000| response to caffeine DHODH;PPARG 19993:[DB14011 DB01667] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01667|8-azaguanine PNP;CYP1A2 common genes CYP1A2 common pathways GO:0006955| immune response PNP;CNR2;OPRD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;PNP;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0010468| regulation of gene expression CYP1A2 19994:[DB14011 DB00282] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00282|Pamidronate FDPS common genes common pathways GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;PTGS1;NAAA;GPX1;FDPS GO:0016032| viral reproduction VDAC1;HTR2A;FDPS GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1;FDPS;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0008299| isoprenoid biosynthetic process HMGCR;FDPS GO:0045540| regulation of cholesterol biosynthetic process HMGCR;FDPS GO:0008203| cholesterol metabolic process HMGCR;CAT;FDPS GO:0006695| cholesterol biosynthetic process HMGCR;FDPS GO:0006694| steroid biosynthetic process HMGCR;FDPS;CYP17A1 19995:[DB14011 DB06831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06831|2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE PIK3CG;PIK3CD common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV4;TRPV1;PIK3CG GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;SMPD1;PIK3CD;GPR18;PPARG;CACNA1I;PLA2G1B GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;PIK3CG;PIK3CD GO:0001525| angiogenesis PTGS2;PIK3CG;CYP1B1 GO:0071320| cellular response to cAMP PIK3CG;AANAT GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;PIK3CG;PIK3CD;PTGS1;ALOX5;PTGS2;CNR2 GO:0030217| T cell differentiation PIK3CD;GPR18 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;PIK3CG;GPR18 GO:0043085| positive regulation of catalytic activity PIK3CG;SOD1 GO:0002376| immune system process PIK3CG;PIK3CD;IDO1 GO:0043406| positive regulation of MAP kinase activity HTR2A;PIK3CG GO:0010628| positive regulation of gene expression PIK3CD;TRPV4 GO:0045087| innate immune response PIK3CG;PPARG;PIK3CD GO:0030593| neutrophil chemotaxis PLA2G1B;PIK3CG;PIK3CD GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CD;PIK3CG;GPX1 19996:[DB14011 DB05016] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0055085| transmembrane transport TRPV2;SLCO1B3;SLC22A8;CACNA1H;TRPV3;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;CACNA1G;SLC22A6;ABCC1 GO:0006811| ion transport CACNA1H;TRPV3;SLCO1B3;GLRA3;SLC22A8;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;SLC22A8 GO:0098656| SLC22A6;VDAC1;SLC22A8 19997:[DB14011 DB01341] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways GO:0006810| transport GABRA1;TRPV2;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;GLRA3;GABRA1 GO:0006821| chloride transport GLRB;GLRA1;GLRA3;GABRA1 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;GABRA1;TRPV3;CACNA1H;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;GLRA1;TRPA1;CACNA1G GO:0060078| regulation of postsynaptic membrane potential GABRA1;CHRNA7 GO:1902476| GLRA1;GLRB;GABRA1;GLRA3 19998:[DB14011 DB02183] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;HINT1 GO:0006915| apoptotic process VDAC1;HINT1;GPX1 GO:0006351| transcription, DNA-dependent HINT1;PPARG GO:0007165| signal transduction OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;HINT1;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I 19999:[DB14011 DB00129] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways GO:0006810| transport TRPV2;SLC7A4;TRPV1;CACNA1I;ABCG2;SLC7A1;ABCC1;SLC7A2 GO:0007568| aging CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT;ARG1 GO:0009611| response to wounding GPX1;ARG1;CYP1A1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;ARG2;GPR18 GO:0002376| immune system process IDO1;ARG1;ARG2 GO:0046686| response to cadmium ion CAT;ARG1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ARG1 GO:0042130| negative regulation of T cell proliferation ARG1;IDO1 GO:0001657| ureteric bud development ARG2;CAT GO:0007283| spermatogenesis OAZ3;CNR1;SOD1 GO:0030324| lung development ARG1;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;ARG1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0007611| learning or memory GATM;CNR1;CHRNA7 GO:0033197| response to vitamin E ARG1;CAT GO:0060135| maternal process involved in female pregnancy ARG1;CNR1 GO:0045087| innate immune response ARG2;ARG1;PPARG GO:0043312| neutrophil degranulation ALOX5;CAT;ARG1 GO:0070207| protein homotrimerization OTC;ARG1;TRPM8 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;OTC;CAT;ARG1;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT;ARG1 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0007601| visual perception GLRB;CYP1B1;OAT;GLRA1;CRYZ GO:0043434| response to peptide hormone stimulus ARG1;TRPV1 GO:0032868| response to insulin stimulus TRPV4;AANAT;OTC;CAT GO:0006809| nitric oxide biosynthetic process ARG2;SLC7A2;CYP1B1 GO:0010269| response to selenium ion ARG1;GPX1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ARG1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway ARG1;PPARG GO:0010043| response to zinc ion ARG1;OTC;AANAT GO:0001889| liver development ARG1;OTC;ACAT1;CYP1A1 GO:0048678| response to axon injury SOD1;ARG1 GO:0050727| regulation of inflammatory response SLC7A2;PTGS2 GO:0007565| female pregnancy IDO1;ARG1 GO:0009635| response to herbicide CYP1A1;ARG1 GO:0031667| response to nutrient levels SOD1;OTC 20000:[DB14011 DB05467] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05467|R667 RARG common genes common pathways GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;RARG;OPRM1;PTGS2 GO:0043010| camera-type eye development RARG;CYP1A1 GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;RARG;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0010628| positive regulation of gene expression TRPV4;RARG GO:0010468| regulation of gene expression CYP1A2;RARG GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0032526| response to retinoic acid RARG;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;RARG;PTGS2;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;RARG;CAT GO:0071300| cellular response to retinoic acid RARG;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARG;TRPV4;TRPV1 20001:[DB14011 DB08868] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0034599| cellular response to oxidative stress GPX1;CAT;SOD1;GSR;HDAC1 GO:0032496| response to lipopolysaccharide CYP1A1;HDAC1;IDO1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;HDAC1;TRPV1;TRPV4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP4F12;CYP1A2;CYP2C19;CYP1B1;CYP4F2;CYP2C9;CYP1A1 GO:0043066| negative regulation of apoptotic process HDAC1;GPX1;CAT;SPHK1;PTGS2;HMGCR;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;HDAC1;PLA2G1B GO:0008284| positive regulation of cell proliferation HDAC1;HTR2A;HTR1A;HMGCR;PTGS2;SPHK1;CHRNA7 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP2E1;CYP4F12;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP4F2;CYP1A1;CYP2C9;CRYZ GO:0045893| positive regulation of transcription, DNA-dependent HDAC1;PPARG GO:0042493| response to drug ABCG2;CYP1A1;PPARG;HDAC1;TRPA1;SMPD1;ABCC1;CAT;CYP2E1;HTR2A;SOD1;CYP1A2;PTGS2 GO:0006691| leukotriene metabolic process ALOX15;CYP4F2;ABCC1;ALOX5 GO:0006355| regulation of transcription, DNA-dependent PPARG;HDAC1 GO:0055093| response to hyperoxia HDAC1;CYP1A1;CAT GO:0019369| arachidonic acid metabolic process DAGLA;CYP2D6;ALOX15;CYP4F2;CYP1B1;CYP4F12;FAAH GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2E1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;S1PR5;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP4F2;CYP3A4;CYP2E1;CYP4F12;CYP1A2 GO:0045766| positive regulation of angiogenesis CYP1B1;SPHK1;CHRNA7 GO:0045892| negative regulation of transcription, DNA-dependent HDAC1;PPARG GO:0031000| response to caffeine PPARG;HDAC1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC1 GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC1 GO:0048511| rhythmic process AANAT;PPARG;HDAC1 GO:0010193| response to ozone CAT;CYP2E1 GO:0006351| transcription, DNA-dependent HDAC1;PPARG GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0035556| intracellular signal transduction SPHK1;PLA2G1B GO:0008152| metabolic process SMPD1;SPHK1;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0010629| negative regulation of gene expression HDAC1;OPRD1 GO:0043524| negative regulation of neuron apoptosis HDAC1;SOD1 GO:0016032| viral reproduction HTR2A;VDAC1;HDAC1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;SPHK1 GO:0006954| inflammatory response SPHK1;PTGS1;ALOX5;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0001975| response to amphetamine HDAC1;SOD1;CNR2 GO:0006641| triglyceride metabolic process CAT;GPX1;CYP2E1 GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;SPHK1;CHRNA7;GPR18;PPARG;SMPD1;S1PR5;PLA2G1B;CACNA1I GO:0007420| brain development ACAT1;SPHK1 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP4F2;CYP2C19 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;HDAC1;CYP1B1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;CYP4F2 GO:0045987| positive regulation of smooth muscle contraction SPHK1;PTGS2 GO:0048146| positive regulation of fibroblast proliferation SPHK1;PLA2G1B 20002:[DB14011 DB00519] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport TRPV2;SLC15A2;ABCG2;TRPV1;CACNA1I;SLC15A1;ABCC1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;SLC15A1;TRPA1;CACNA1G;ABCC1;TRPV2;SLC15A2;CACNA1H;TRPV3 GO:0030855| epithelial cell differentiation CES1;PPARG;VDAC1 GO:0007283| spermatogenesis ACE;CNR1;SOD1 GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0001822| kidney development CAT;ACE GO:0060047| heart contraction ACE;GPX1;SOD1 GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0006811| ion transport SLC15A1;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;GLRA3;SLC15A2;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0009636| response to toxin CYP1A1;CYP1B1;CES1;GPX1;CAT GO:0008217| regulation of blood pressure ACE;PTGS1;SOD1;PTGS2;PPARG GO:0008152| metabolic process SMPD1;CES1;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CES1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 20003:[DB14011 DB03397] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03397|Uridine-Diphosphate-N-Acetylglucosamine glmU;UAP1;murA;GALE;glmU;EXTL2;MGAT1 common genes common pathways GO:0008152| metabolic process SMPD1;UAP1;ACAT1 20004:[DB14011 DB01908] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01908|RU85493 SRC common genes common pathways GO:0031667| response to nutrient levels SRC;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;SRC GO:0042542| response to hydrogen peroxide SOD1;GPX1;SRC;CAT;TRPA1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0008283| cell proliferation GPX1;SRC;HTR1A;CYP1A1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC GO:0045453| bone resorption GPR55;SRC GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;SRC;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0070542| response to fatty acid CAT;SRC;PTGS2 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;SRC;SOD1;HTR2A;PTGS2;CYP1A2 GO:0016236| macroautophagy SRC;VDAC1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0009615| response to virus CYP1A1;SRC GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;SRC;GPX1;CAT GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0045087| innate immune response PPARG;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;SRC;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0002376| immune system process IDO1;SRC 20005:[DB14011 DB04140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04140|1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide MMP3 common genes common pathways 20006:[DB14011 DB06962] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06962|(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone TPSB2 common genes common pathways 20007:[DB14011 DB06928] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways GO:0008152| metabolic process ACAT1;FOLH1;SMPD1 20008:[DB14011 DB06376] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06376|CHGN111 CLK1 common genes common pathways GO:0008283| cell proliferation HTR1A;CLK1;GPX1;CYP1A1 20009:[DB14011 DB01438] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01438|Phenazopyridine SCN1A common genes common pathways GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;CACNA1H;SCN1A GO:0034220| ion transmembrane transport SCN1A;CHRNA7;GLRA3;TRPV1;GLRB;TRPA1;GLRA1 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2;SCN1A GO:0086002| CACNA1G;SCN1A GO:0001508| regulation of action potential SCN1A;CACNA1G;GLRA1 GO:0007628| adult walking behavior GLRB;GLRA1;SCN1A GO:0050884| neuromuscular process controlling posture SCN1A;GLRA1 GO:0034765| regulation of ion transmembrane transport CACNA1H;SCN1A;CACNA1G;CACNA1I GO:0006811| ion transport VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;SCN1A;CHRNA7;TRPV3;CACNA1H;GLRA3 GO:0035725| sodium ion transmembrane transport CACNA1H;SCN1A;CACNA1G;CACNA1I GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;SCN1A;CACNA1H GO:0050966| detection of mechanical stimulus involved in sensory perception of pain TRPA1;SCN1A;HTR2A GO:0086010| CACNA1I;CACNA1G;SCN1A;CACNA1H 20010:[DB14011 DB02518] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02518|N-Acetylalanine AKR1B1 common genes common pathways GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;AKR1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;PTGS1;ALOX5;GPX1 GO:0022900| electron transport chain AKR1B1;IDO1;GSR;CYP1A2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;AKR1B1 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0043066| negative regulation of apoptotic process AKR1B1;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0010033| response to organic substance AKR1B1;PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 20011:[DB14011 DB01084] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01084|Emedastine HRH1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;HRH1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;HRH1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0008542| visual learning HMGCR;HRH1 GO:0006954| inflammatory response HRH1;PTGS2;CNR2;ALOX5;PTGS1;IDO1;ALOX15;TRPV1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;HRH1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0045907| positive regulation of vasoconstriction HTR2A;HRH1;PTGS2 GO:0007613| memory PTGS2;HRH1;CNR1;HTR2A;CHRNA7 20012:[DB14011 DB02759] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02759|4-Methylumbelliferyl Chitobiose LYZ common genes common pathways GO:0001895| retina homeostasis SOD1;LYZ GO:0008152| metabolic process LYZ;SMPD1;ACAT1 GO:0006954| inflammatory response TRPV1;LYZ;ALOX15;IDO1;ALOX5;PTGS1;CNR2;PTGS2 GO:0043312| neutrophil degranulation LYZ;ALOX5;CAT GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B 20013:[DB14011 DB11327] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11327|Dipyrithione NOS2;PTGS2 common genes PTGS2 common pathways GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0045454| cell redox homeostasis GPX1;GSR;NOS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0050796| regulation of insulin secretion NOS2;CNR1 GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;PTGS2;CNR2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2;TRPA1;TRPV1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;NAAA;GPX1;PTGS1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CAT GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| GSR;PTGS1;GPX1;CAT;PTGS2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;NOS2;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0009750| response to fructose stimulus PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;NOS2;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0007623| circadian rhythm NOS2;AANAT GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;NOS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 20014:[DB14011 DB06083] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06083|Tapinarof IL12B;IL2;IL6;CXCL8 common genes common pathways GO:0007155| cell adhesion CYP1B1;IL2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;IL2;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;PLA2G1B;IL6;PPARG GO:0035722| interleukin-12-mediated signaling pathway SOD1;IL12B GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;IL2;IL6 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;IL6 GO:0050830| defense response to Gram-positive bacterium IL6;PLA2G1B GO:0030593| neutrophil chemotaxis CXCL8;PLA2G1B GO:0045893| positive regulation of transcription, DNA-dependent IL6;PPARG GO:0002862| negative regulation of inflammatory response to antigenic stimulus GPX1;IL12B GO:0050728| negative regulation of inflammatory response IL2;CNR2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;IL6 GO:0032735| positive regulation of interleukin-12 production IL12B;IDO1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;IL2;CXCL8;GPR18;PPARG GO:0002446| neutrophil mediated immunity PLA2G1B;IL6 GO:0032966| negative regulation of collagen biosynthetic process PPARG;IL6 GO:0002376| immune system process IL2;IDO1 GO:0045766| positive regulation of angiogenesis CHRNA7;CXCL8;CYP1B1 GO:0071356| cellular response to tumor necrosis factor TRPV1;CXCL8 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;IL12B;TRPA1;CYP1A1;PPARG GO:0010628| positive regulation of gene expression TRPV4;IL6 GO:0045471| response to ethanol IL2;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0001525| angiogenesis PTGS2;CXCL8;CYP1B1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;IL12B;TRPA1 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;IL12B;TRPV1;TRPA1 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;IL6;CYP1B1;TRPV1 GO:0035556| intracellular signal transduction PLA2G1B;CXCL8 GO:0001934| positive regulation of protein phosphorylation CHRNA7;IL2 GO:0032693| negative regulation of interleukin-10 production IDO1;IL12B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL6 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IL6;PLA2G1B GO:0030217| T cell differentiation GPR18;IL2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;ALOX15;IDO1;CXCL8;TRPV1;IL6 GO:0006955| immune response IL2;IL6;CXCL8;OPRD1;CNR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;PPARG GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;IL2;TRPV1;TRPV4 GO:0051384| response to glucocorticoid stimulus IL6;PTGS2 GO:0050729| positive regulation of inflammatory response IL12B;TRPV4;IL2 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;CXCL8;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;IL6 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IL12B GO:0008283| cell proliferation CYP1A1;IL12B;HTR1A;GPX1 GO:0070301| cellular response to hydrogen peroxide IL6;CYP1B1 GO:0061844| PLA2G1B;CXCL8 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;CXCL8;IL6;OPRM1;PTGS2 GO:0034976| response to endoplasmic reticulum stress CXCL8;ALOX15 20015:[DB14011 DB00626] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00626|Bacitracin IDE;A2M common genes common pathways GO:0051260| protein homooligomerization IDE;GLRA1;GLRA3;ACAT1 GO:0002576| platelet degranulation A2M;SOD1 GO:0046718| entry of virus into host cell IDE;HTR2A GO:0051291| protein heterooligomerization GLRB;GLRA1;IDE GO:0008152| metabolic process SMPD1;IDE;ACAT1 GO:0051289| protein homotetramerization CAT;IDE;TRPA1;CRYZ;TRPV1;TRPM8 GO:0016032| viral reproduction HTR2A;VDAC1;IDE 20016:[DB14011 DB07288] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;FLT1;HTR2A;HTR1A GO:0048514| blood vessel morphogenesis FLT1;CYP1B1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FLT1 GO:0043406| positive regulation of MAP kinase activity HTR2A;FLT1 GO:0045766| positive regulation of angiogenesis CHRNA7;FLT1;CYP1B1 GO:0001525| angiogenesis FLT1;PTGS2;CYP1B1 20017:[DB14011 DB02445] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 20018:[DB14011 DB00583] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0007568| aging CYP1A1;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT;MPO GO:0006979| response to oxidative stress GPX1;MPO;PTGS1;CAT;PTGS2;SOD1 GO:0051260| protein homooligomerization GLRA1;GLRA3;ACAT1;CPT1A GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0030855| epithelial cell differentiation PPARG;VDAC1;CES1;CPT1A GO:0055085| transmembrane transport SLC22A8;SLC22A5;SLC22A16;SLCO1B1;SLC22A4;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;SLC25A29;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;SLC22A4;TRPV1;GLRB;GLRA1;TRPA1 GO:0007283| spermatogenesis CNR1;SOD1;SLC22A16 GO:0030317| sperm motility SLC22A16;CACNA1I GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0006635| fatty acid beta-oxidation ACAT1;CROT;CPT1A;CPT2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MPO;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0007623| circadian rhythm CPT1A;AANAT GO:0043312| neutrophil degranulation ALOX5;MPO;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;MPO GO:0043066| negative regulation of apoptotic process CAT;MPO;GPX1;SOD1;PTGS2;HMGCR GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;XDH;CAT;MPO;GPX1;ALOX5;PTGS1 GO:0006631| fatty acid metabolic process CROT;PTGS1;CPT1A;CRAT;PTGS2;ALOX15;CPT2 GO:0022900| electron transport chain GSR;IDO1;CYP1A2;XDH GO:0032094| response to food CYP1A1;MPO;OPRM1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CPT1A;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0050796| regulation of insulin secretion CNR1;CPT1A GO:0019216| regulation of lipid metabolic process CPT1A;CNR1;HMGCR;CYP1A1;PPARG;CPT2 GO:0015936| coenzyme A metabolic process HMGCR;CROT;ACAT1 GO:0006641| triglyceride metabolic process CAT;GPX1;CPT1A;SLC22A4 GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A5 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CPT1A;AANAT;ACAT1;CYP1A2;PTGS2 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;CES1;SLC22A8 GO:0006919| activation of caspase activity PPARG;XDH GO:0042755| eating behavior CPT1A;OPRM1;OPRD1 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;SLCO1B1;SLC22A8;SLC22A16;SLC22A5;GLRA3;TRPV3;SLC22A4;CACNA1H;CHRNA7;TRPV2 GO:0098656| VDAC1;SLC22A8 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;CPT2;CYP2C9;PPARG;CPT1A;NAAA;CROT;PTGS1;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;CRAT GO:0008152| metabolic process ACAT1;CES1;SMPD1 GO:0006805| xenobiotic metabolic process CYP3A4;CES1;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0006195| purine nucleotide catabolic process XDH;GPX1 GO:0010629| negative regulation of gene expression OPRD1;XDH GO:0007595| lactation SLC29A1;XDH GO:0019430| removal of superoxide radicals MPO;SOD1 20019:[DB14011 DB05944] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05944|Varlitinib ERBB2;EGFR common genes common pathways GO:0007202| activation of phospholipase C activity EGFR;GPR55;HTR2A GO:0010628| positive regulation of gene expression ERBB2;TRPV4 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;ERBB2;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;EGFR GO:0006979| response to oxidative stress EGFR;PTGS2;SOD1;GPX1;PTGS1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TRPV1;PTGS2;OPRM1 GO:0033993| response to lipid PPARG;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2;CYP1A2;CAT GO:0071363| cellular response to growth factor stimulus EGFR;TRPV1;ERBB2;CAT;OPRD1 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2;HMGCR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;GPX1;ERBB2 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ERBB2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;EGFR GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0007611| learning or memory EGFR;CNR1;CHRNA7 GO:0007623| circadian rhythm EGFR;AANAT GO:0042127| regulation of cell proliferation PTGS2;PTGS1;EGFR GO:0042060| wound healing EGFR;ALOX15;ERBB2;OPRM1 GO:0030324| lung development EGFR;CYP1A2 GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication EGFR;PLA2G1B GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;EGFR GO:0032930| positive regulation of superoxide anion generation SOD1;EGFR GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;EGFR;CYP1A2;PTGS2;AANAT;ACAT1 GO:0008283| cell proliferation ERBB2;GPX1;HTR1A;EGFR;CYP1A1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;EGFR GO:0014065| phosphatidylinositol 3-kinase cascade ERBB2;HTR2A GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2;OPRD1 GO:0007165| signal transduction ERBB2;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;EGFR;PPARG;GPR18;SMPD1 GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7;ERBB2 GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0001503| ossification EGFR;ALOX15 GO:0007507| heart development PPARG;ERBB2 GO:0007399| nervous system development GLRB;SMPD1;ERBB2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR;ERBB2 GO:0006970| response to osmotic stress TRPV4;EGFR GO:0051592| response to calcium ion AANAT;EGFR GO:0001889| liver development ACAT1;EGFR;CYP1A1 GO:0006351| transcription, DNA-dependent PPARG;ERBB2 GO:0007166| cell surface receptor linked signaling pathway ERBB2;TRPA1;EGFR;TRPV1 20020:[DB14011 DB05009] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05009|Apadenoson ADORA2A common genes common pathways GO:0050728| negative regulation of inflammatory response ADORA2A;CNR2 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ADORA2A;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;ADORA2A GO:0007626| locomotory behavior OPRM1;SOD1;ADORA2A GO:0042311| vasodilation ADORA2A;GPX1 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;GLRA1;ADORA2A;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0031000| response to caffeine ADORA2A;PPARG GO:0050714| positive regulation of protein secretion ADORA2A;PLA2G1B GO:0006915| apoptotic process GPX1;ADORA2A;VDAC1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADORA2A;GPR18;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;ADORA2A;ALOX5;PTGS1;CNR2;PTGS2 GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0007600| sensory perception OPRM1;TRPV2;ADORA2A GO:0043524| negative regulation of neuron apoptosis SOD1;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;ADORA2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADORA2A GO:0008285| negative regulation of cell proliferation ADORA2A;PPARG;CYP1B1;OPRM1;PTGS2 GO:0042755| eating behavior OPRM1;OPRD1;ADORA2A GO:0051881| regulation of mitochondrial membrane potential ADORA2A;OPRD1;SOD1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;ADORA2A;GPR18;PPARG GO:0001975| response to amphetamine SOD1;CNR2;ADORA2A 20021:[DB14011 DB05281] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0010332| response to gamma radiation GPX1;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BCL2;PTGS2 GO:0051384| response to glucocorticoid stimulus BCL2;PTGS2 GO:0072593| reactive oxygen species metabolic process BCL2;SOD1 GO:0030336| negative regulation of cell migration BCL2;CYP1B1 GO:0009791| post-embryonic development CYP1A2;BCL2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1;BCL2 GO:0001662| behavioral fear response VDAC1;HTR1A;BCL2 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;BCL2 GO:0008283| cell proliferation GPX1;HTR1A;BCL2;CYP1A1 GO:2000378| negative regulation of reactive oxygen species metabolic process BCL2;VDAC1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;BCL2 GO:0009314| response to radiation BCL2;PTGS2;OPRM1;CAT GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;BCL2;TRPA1 GO:0001503| ossification ALOX15;BCL2 GO:0030217| T cell differentiation BCL2;GPR18 GO:0051924| regulation of calcium ion transport OPRD1;BCL2 GO:0043524| negative regulation of neuron apoptosis SOD1;BCL2 GO:0007565| female pregnancy IDO1;BCL2 GO:0008631| induction of apoptosis by oxidative stress GPX1;BCL2;CYP1B1 GO:0006874| cellular calcium ion homeostasis CHRNA7;BCL2;HTR2A;GPR12;TRPV4;TRPM8 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;BCL2 GO:0048538| thymus development BCL2;SOD1 GO:0043085| positive regulation of catalytic activity BCL2;SOD1 GO:0010468| regulation of gene expression BCL2;CYP1A2 GO:0071456| cellular response to hypoxia OPRD1;BCL2;PTGS2;SLC29A1 GO:0001657| ureteric bud development BCL2;CAT GO:0001541| ovarian follicle development SOD1;BCL2 GO:0006915| apoptotic process VDAC1;GPX1;BCL2 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;BCL2;TRPV2 GO:0043066| negative regulation of apoptotic process SOD1;BCL2;HMGCR;PTGS2;CAT;GPX1 GO:0001822| kidney development CAT;BCL2 GO:0008284| positive regulation of cell proliferation PTGS2;BCL2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0002576| platelet degranulation TUBA4A;SOD1 GO:0034097| response to cytokine stimulus AANAT;PTGS2;BCL2 GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0035094| response to nicotine BCL2;CNR1;CHRNA7 GO:0007015| actin filament organization BCL2;TRPV4;PLA2G1B GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;BCL2;ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0007569| cell aging SOD1;BCL2 20022:[DB14011 DB11311] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11311|Prothrombin FGA;FGB;F13A1;CPB2;F10 common genes common pathways GO:0071333| cellular response to glucose stimulus CPB2;SLC29A1 GO:0045087| innate immune response FGA;PPARG;FGB GO:0002576| platelet degranulation F13A1;FGA;SOD1;FGB GO:0042493| response to drug CAT;CPB2;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 GO:0002376| immune system process FGA;IDO1;FGB GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;FGB;CHRNA7;FGA;TRPV4;ALOX15 GO:0050714| positive regulation of protein secretion PLA2G1B;FGA;FGB GO:0051592| response to calcium ion FGB;AANAT;FGA GO:0009408| response to heat CPB2;TRPV2;SOD1;TRPV3;TRPV1 GO:0034116| positive regulation of heterotypic cell-cell adhesion FGB;ALOX15;FGA GO:0007165| signal transduction HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;FGB;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;FGA GO:0045907| positive regulation of vasoconstriction FGA;PTGS2;HTR2A;FGB GO:1902042| FGA;GPX1;FGB 20023:[DB14011 DB08277] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08277|2-(2-CHLORO-4-FLUOROPHENOXY)-2-METHYL-N-[(1R,2S,3S,5S,7S)-5-(METHYLSULFONYL)-2-ADAMANTYL]PROPANAMIDE HSD11B1 common genes common pathways GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;HSD11B1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HSD11B1;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ GO:0030324| lung development CYP1A2;HSD11B1 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;HSD11B1;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B1 20024:[DB14011 DB08391] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0008152| metabolic process PDE10A;ACAT1;SMPD1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PDE10A;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;PDE10A;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 20025:[DB14011 DB07775] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0006810| transport ABCC1;ABCG2;CACNA1I;TRPV1;TTR;TRPV2 GO:0043312| neutrophil degranulation TTR;CAT;ALOX5 20026:[DB14011 DB07866] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07866|(5S)-2-(cyclooctylamino)-5-methyl-5-propyl-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;HSD11B1;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0030324| lung development HSD11B1;CYP1A2 GO:0006704| glucocorticoid biosynthetic process HSD11B1;CYP17A1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;HMGCR;CYP3A7;CYP1A2;CYP3A4;HSD11B1 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;HSD11B1 20027:[DB14011 DB06439] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06439|Tyloxapol LPL common genes common pathways GO:0006644| phospholipid metabolic process PLA2G1B;LPL;NAPEPLD GO:0016042| lipid catabolic process NAPEPLD;DAGLA;PLA2G1B;LPL GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;LPL;ABCG2 GO:0006633| fatty acid biosynthetic process PLA2G1B;LPL;PTGS2;PTGS1 GO:0006641| triglyceride metabolic process LPL;CAT;GPX1 GO:0050729| positive regulation of inflammatory response LPL;TRPV4 GO:0001523| retinoid metabolic process LPL;NAPEPLD GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;LPL;PPARG;CYP2C9;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR GO:0009409| response to cold PPARG;TRPA1;LPL;TRPM8 20028:[DB14011 DB12702] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12702|Velusetrag HTR4 common genes common pathways GO:0007268| synaptic transmission HTR4;OPRM1;OPRD1;GLRA3;HTR2A;CACNA1G;GLRA1;VDAC1;GLRB GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;HTR4;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;HTR4;OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;HTR4;CNR2;OPRM1 20029:[DB14011 DB03554] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03554|5-Iodouracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;ALOX5;GPX1;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP2C9;CYP1A1;CRYZ 20030:[DB14011 DB08473] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08473|5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole CSNK2A1 common genes common pathways GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG GO:0006915| apoptotic process GPX1;CSNK2A1;VDAC1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CSNK2A1;CHRNA7 GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CSNK2A1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0006351| transcription, DNA-dependent CSNK2A1;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1;GPX1 20031:[DB14011 DB04356] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes CYP1A2 common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0007626| locomotory behavior OPRM1;SOD1;HPRT1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPV1;HPRT1;TRPM8;CAT GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;ACAT1;AANAT GO:0045333| cellular respiration CYP1A2 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0001975| response to amphetamine HPRT1;CNR2;SOD1 20032:[DB14011 DB08056] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;LCK;TRPV1 GO:0045087| innate immune response PPARG;LCK GO:0042127| regulation of cell proliferation PTGS2;PTGS1;LCK GO:0051897| positive regulation of protein kinase B signaling cascade LCK;GPX1 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;LCK GO:0006919| activation of caspase activity PPARG;LCK GO:0016032| viral reproduction HTR2A;LCK;VDAC1 GO:0030217| T cell differentiation LCK;GPR18 20033:[DB14011 DB07124] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07124|(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE PRKACA common genes common pathways GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0071333| cellular response to glucose stimulus SLC29A1;PRKACA GO:0034605| cellular response to heat PRKACA;PTGS2;TRPV1;TRPV4 20034:[DB14011 DB00692] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;ADRA1B;ADRA1D;ADRA1A GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ADRA1A;ABCG2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042593| glucose homeostasis ADRA2A;TRPV4;PPARG;ADRA1B;CNR1 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;ADRA1A;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;ADRA1B;ADRA1D;PPARG;GPR18;ADRA1A;ADRA2A GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A GO:0007202| activation of phospholipase C activity HTR2A;GPR55;ADRA1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ADRA1A;TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0006915| apoptotic process VDAC1;ADRA1A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRA1D;ADRA1B;CNR1 GO:0035556| intracellular signal transduction ADRA1B;ADRA1A;PLA2G1B GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0007165| signal transduction CHRNA7;ADRA1B;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;ADRA2A;CACNA1I;ADRA1A;PLA2G1B;GPR18;PPARG;SMPD1;ADRA1D GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0045907| positive regulation of vasoconstriction ADRA1B;HTR2A;PTGS2;ADRA1A;ADRA1D GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;ADRA1B;ADRA1D;TRPV1;ADRA1A;TRPV4 GO:0050796| regulation of insulin secretion CNR1;ADRA2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRM1;OPRD1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;ADRA1A;OPRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1D;ADRA1A GO:0008283| cell proliferation ADRA1B;GPX1;HTR1A;CYP1A1;ADRA1D 20035:[DB14011 DB07167] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;CNR2;PTGS2;CSF1R;ALOX5;PTGS1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;CSF1R GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CSF1R;PPARG;CYP1B1 GO:0008283| cell proliferation CSF1R;GPX1;HTR1A;CYP1A1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;CSF1R;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0071345| cellular response to cytokine stimulus TRPV1;CSF1R GO:0030224| monocyte differentiation CSF1R;PPARG GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;CSF1R GO:0043066| negative regulation of apoptotic process CAT;GPX1;CSF1R;SOD1;PTGS2;HMGCR GO:0045087| innate immune response CSF1R;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade CSF1R;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0002376| immune system process CSF1R;IDO1 20036:[DB14011 DB01303] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes CYP1A2 common pathways GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0045333| cellular respiration CYP1A2 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADORA1 GO:0006811| ion transport TRPV2;SLC22A7;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0042755| eating behavior ADORA2A;OPRD1;OPRM1 GO:0032229| negative regulation of synaptic transmission, GABAergic ADORA1;CNR2 GO:0045777| positive regulation of blood pressure CNR1;ADORA1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1;ADORA2A GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0008285| negative regulation of cell proliferation ADORA2A;PPARG;ADORA1;CYP1B1;OPRM1;PTGS2 GO:0098656| VDAC1;SLC22A7 GO:0070301| cellular response to hydrogen peroxide HDAC2;CYP1B1 GO:0001975| response to amphetamine ADORA2A;SOD1;CNR2;HDAC2 GO:0050890| cognition ADORA1;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADORA1 GO:0043117| positive regulation of vascular permeability TRPV4;PDE3A GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0007165| signal transduction CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;PDE4A;CNR2;OPRM1;CHRNA7;ADORA2A;GPR18;ADORA1;PPARG;SMPD1;PDE3A;CACNA1I;PLA2G1B GO:0048149| behavioral response to ethanol OPRM1;HDAC2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2;GPX1 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;ADORA2A;ADORA1;PTGS1;ALOX5;CNR2;PTGS2 GO:0007600| sensory perception ADORA2A;OPRM1;TRPV2 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;ADORA1;HTR2A GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0006351| transcription, DNA-dependent HDAC2;PPARG GO:0045776| negative regulation of blood pressure CNR1;ADORA1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0001659| temperature homeostasis HTR2A;GPX1;ADORA1;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADORA2A GO:0006629| lipid metabolic process PDE3A;CYP2C9;PPARG;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0007399| nervous system development GLRB;ADORA1;SMPD1 GO:0051591| response to cAMP PDE3A;AANAT GO:0016042| lipid catabolic process DAGLA;PLA2G1B;ADORA1;NAPEPLD GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0006915| apoptotic process GPX1;VDAC1;ADORA2A GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0042220| response to cocaine HDAC2;CNR1;OPRM1;SMPD1 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC22A7;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;CACNA1I;TRPV4;VDAC1 GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;ADORA1 GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0010977| negative regulation of neuron projection development TRPV4;HDAC2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0031000| response to caffeine ADORA2A;PPARG;HDAC2 GO:0045892| negative regulation of transcription, DNA-dependent HDAC2;PPARG GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0048511| rhythmic process HDAC2;AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation HDAC2;PPARG GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0034605| cellular response to heat PTGS2;HDAC2;TRPV1;TRPV4 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PDE3A;ADORA1;PPARG;ADORA2A;GPR18;CNR2;OPRM1;OPRD1;PDE4A;HTR1A;GPR55;CNR1;GPR12;HTR2A GO:0097756| ADORA1;HMGCR;PTGS2 GO:0010468| regulation of gene expression CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;HDAC2 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0042493| response to drug HDAC2;CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;ADORA2A;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;PDE3A GO:0006355| regulation of transcription, DNA-dependent HDAC2;PPARG;ADORA2A GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA1 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ;ALOX5;PTGS1;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0055093| response to hyperoxia CYP1A1;HDAC2;CAT GO:0050728| negative regulation of inflammatory response CNR2;ADORA1;ADORA2A GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;ADORA1 GO:0035094| response to nicotine HDAC2;CHRNA7;CNR1 GO:0032496| response to lipopolysaccharide HDAC2;CNR1;PTGS2;CNR2;CYP1A2;OPRM1;IDO1;CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;ADORA1;ADORA2A;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0071300| cellular response to retinoic acid HDAC2;PPARG GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0042311| vasodilation GPX1;ADORA2A GO:0032259| methylation CYP1A2 GO:0043066| negative regulation of apoptotic process ADORA1;PDE3A;SOD1;HMGCR;PTGS2;CAT;HDAC2;GPX1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;HDAC2;CHRNA7 GO:0007626| locomotory behavior ADORA2A;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;PPARG;PLA2G1B GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0035307| positive regulation of protein dephosphorylation SMPD1;ADORA1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;HDAC2 20037:[DB14011 DB08341] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;PTK2B GO:0043066| negative regulation of apoptotic process PTK2B;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;PTK2B GO:0071300| cellular response to retinoic acid PPARG;PTK2B GO:0007155| cell adhesion CYP1B1;PTK2B GO:0045087| innate immune response PTK2B;PPARG GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;PTK2B GO:0000302| response to reactive oxygen species PTK2B;CAT;GPX1;SOD1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PTK2B GO:0030838| positive regulation of actin filament polymerization PTK2B;ALOX15 GO:0046330| positive regulation of JNK cascade TRPV4;PTK2B GO:0010243| response to organic nitrogen PTGS2;TRPV1;PTK2B GO:0007015| actin filament organization PTK2B;PLA2G1B;TRPV4 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;PTK2B;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0002376| immune system process IDO1;PTK2B GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;PTK2B;TRPV1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;PTK2B GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;PTK2B GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;PTK2B GO:0051591| response to cAMP AANAT;PTK2B GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;PTK2B;ALOX15 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;PTK2B GO:0042220| response to cocaine SMPD1;PTK2B;CNR1;OPRM1 GO:0006915| apoptotic process GPX1;VDAC1;PTK2B GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;PTK2B;TRPA1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;PTK2B GO:0006970| response to osmotic stress PTK2B;TRPV4 GO:0045471| response to ethanol PTK2B;CAT;CNR1;SOD1;OPRM1;HMGCR GO:0007166| cell surface receptor linked signaling pathway TRPV1;PTK2B;TRPA1 GO:0001525| angiogenesis PTGS2;CYP1B1;PTK2B GO:0051592| response to calcium ion PTK2B;AANAT GO:0010976| positive regulation of neuron projection development CNR1;PTK2B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation PTK2B;HTR2A GO:0071498| cellular response to fluid shear stress PTK2B;PTGS2 GO:0043524| negative regulation of neuron apoptosis SOD1;PTK2B GO:0043534| blood vessel endothelial cell migration GPX1;PTK2B GO:0045453| bone resorption PTK2B;GPR55 GO:0009725| response to hormone stimulus PTK2B;ACAT1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;PTK2B;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7 GO:0010226| response to lithium ion PTK2B;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;PTK2B GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTK2B;OPRM1;PTGS2 GO:0043267| negative regulation of potassium ion transport HTR2A;PTK2B 20038:[DB14011 DB13627] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13627|Oxolinic acid CYP1A2 common genes CYP1A2 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;GPX1;NAAA;PTGS1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0010468| regulation of gene expression CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;PTGS2;CNR2;CYP1A2;OPRM1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;PTGS1;ALOX5;GPX1 20039:[DB14011 DB07515] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07515|1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL F2 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG;F2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0061844| F2;PLA2G1B 20040:[DB14011 DB05036] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways GO:0006351| transcription, DNA-dependent SCYL1;PPARG GO:0006693| prostaglandin metabolic process PTGS1;PTGS2;PTGES3 GO:0006805| xenobiotic metabolic process PTGS1;PTGES3;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;PTGES3;NAAA;PTGS1;GPX1 GO:0010629| negative regulation of gene expression TERT;OPRD1 GO:0019371| cyclooxygenase pathway PTGES3;PTGS2;PTGS1 GO:0043524| negative regulation of neuron apoptosis SOD1;TERT GO:1900087| CYP1A1;TERT GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGES3;PTGS1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PTGES3;CHRNA7 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2;PTGES3 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;TERT;PTGS2;SOD1 GO:0006355| regulation of transcription, DNA-dependent PPARG;SCYL1 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGES3;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;TERT;SLC29A1 GO:0046686| response to cadmium ion TERT;CAT GO:0045766| positive regulation of angiogenesis CHRNA7;TERT;CYP1B1 20041:[DB14011 DB07969] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;TRPV1;TRPA1 GO:0008283| cell proliferation GPX1;HTR1A;MET;CYP1A1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;MET;CHRNA7 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG;PLA2G1B 20042:[DB14011 DB03902] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03902|Oxalic Acid SRC;SLCO2B1;SLC22A8 common genes common pathways GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC22A8;TRPV2;CACNA1G;ABCC1;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;SLCO2B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0002376| immune system process IDO1;SRC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug CAT;SRC;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;SRC;GPX1;CAT GO:0009615| response to virus SRC;CYP1A1 GO:0009636| response to toxin SLC22A8;CAT;GPX1;CYP1A1;CYP1B1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;SRC GO:0006811| ion transport SLCO2B1;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;SLC22A8;TRPV3;CACNA1H GO:0098656| VDAC1;SLC22A8 GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;SRC;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0045453| bone resorption SRC;GPR55 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0031667| response to nutrient levels SRC;SOD1 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0042542| response to hydrogen peroxide TRPA1;GPX1;SRC;CAT;SOD1 GO:0043065| positive regulation of apoptotic process SRC;PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG 20043:[DB14011 DB04249] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04249|Zinc Substituted Heme C CYCS common genes common pathways GO:0006915| apoptotic process CYCS;GPX1;VDAC1 GO:0034599| cellular response to oxidative stress GSR;SOD1;CYCS;GPX1;CAT GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;CYCS;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0045333| cellular respiration CYCS;CYP1A2 20044:[DB14011 DB01890] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0050714| positive regulation of protein secretion PLA2G1B;IGF1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;IGF1 GO:0001666| response to hypoxia CYP1A1;PPARA;CHRNA7;CAT GO:0010628| positive regulation of gene expression TRPV4;IGF1 GO:0048511| rhythmic process PPARG;AANAT;PPARA GO:0010468| regulation of gene expression PPARA;CYP1A2;IGF1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade IGF1;CAT GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0043388| positive regulation of DNA binding IGF1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG GO:0007517| muscle organ development CACNA1H;IGF1 GO:0045893| positive regulation of transcription, DNA-dependent IGF1;PPARG;PPARA GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PPARA;PTGS2 GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;IGF1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG GO:0042060| wound healing ALOX15;OPRM1;PPARA GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;IGF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IGF1;PLA2G1B;PPARA GO:0002576| platelet degranulation IGF1;SOD1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;IGF1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TRPV1;TRPV4 GO:0008283| cell proliferation HTR1A;GPX1;IGF1;CYP1A1 GO:0051450| myoblast proliferation IGF1;GPX1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0032868| response to insulin stimulus PPARA;CAT;AANAT;TRPV4 GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0048146| positive regulation of fibroblast proliferation IGF1;PLA2G1B GO:0045740| positive regulation of DNA replication PLA2G1B;IGF1 GO:0040014| regulation of multicellular organism growth SOD1;IGF1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;IGF1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARA;CYP1A1;PPARG GO:0014065| phosphatidylinositol 3-kinase cascade IGF1;HTR2A GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;IGF1;GPR18;PPARG GO:0045445| myoblast differentiation IGF1;HMGCR GO:0009408| response to heat IGF1;TRPV1;TRPV3;SOD1;TRPV2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IGF1 GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0045821| positive regulation of glycolysis IGF1;HTR2A GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0006351| transcription, DNA-dependent PPARA;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0007507| heart development PPARG;PPARA GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG;GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;PPARA 20045:[DB14011 DB03220] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03220|FR233623 ADA common genes common pathways GO:0007568| aging CYP1A1;ADA;CAT;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD GO:0001666| response to hypoxia ADA;CAT;CHRNA7;CYP1A1 GO:0030324| lung development CYP1A2;ADA GO:0033197| response to vitamin E CAT;ADA GO:0007155| cell adhesion ADA;CYP1B1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;ADA GO:0042493| response to drug CAT;ADA;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1 GO:0043278| response to morphine CNR1;OPRM1;ADA GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0001890| placenta development SOD1;ADA;PPARG GO:0001889| liver development ADA;ACAT1;CYP1A1 GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;ADA;SOD1 20046:[DB14011 DB08237] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08237|2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) POLK common genes common pathways GO:0034644| cellular response to UV POLK;PTGS2 20047:[DB14011 DB03899] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03899|9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine HSP90AA1 common genes common pathways GO:0009409| response to cold HSP90AA1;PPARG;TRPA1;TRPM8 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;HSP90AA1;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AA1 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;PTGS2;OPRM1 20048:[DB14011 DB14014] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14014|SR-9011 NR1D2;NR1D1 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway NR1D1;PPARG;NR1D2 GO:0045598| regulation of fat cell differentiation PPARG;NR1D1 GO:0006351| transcription, DNA-dependent NR1D2;NR1D1;PPARG GO:0050727| regulation of inflammatory response NR1D2;PTGS2 GO:0042752| regulation of circadian rhythm NR1D2;PPARG;NR1D1 GO:0019216| regulation of lipid metabolic process NR1D1;CYP1A1;PPARG;HMGCR;CNR1;NR1D2 GO:0055088| lipid homeostasis PPARG;NR1D2 GO:0007623| circadian rhythm AANAT;NR1D1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;NR1D1;PPARG;NR1D2 GO:0006355| regulation of transcription, DNA-dependent NR1D2;NR1D1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1D1;NR1D2 GO:0006367| transcription initiation from RNA polymerase II promoter NR1D2;PPARG;NR1D1 GO:0010871| negative regulation of receptor biosynthetic process PPARG;NR1D1 GO:0048511| rhythmic process AANAT;NR1D2;PPARG;NR1D1 GO:0045892| negative regulation of transcription, DNA-dependent NR1D1;PPARG;NR1D2 20049:[DB14011 DB00535] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0032094| response to food MPO;OPRM1;CYP1A1 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;MPO;ALOX5;PTGS1;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6 GO:0043066| negative regulation of apoptotic process MPO;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;MPO GO:0043312| neutrophil degranulation CAT;ALOX5;MPO GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;MPO;CYP1A1;IDO1 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;SLC15A1;CACNA1G;SLC22A6;ABCC1;TRPV2;SLC15A2;SLC22A5;SLC22A8;CACNA1H;TRPV3 GO:0042744| hydrogen peroxide catabolic process MPO;GPX1;CAT GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0006979| response to oxidative stress CAT;GPX1;MPO;PTGS1;SOD1;PTGS2 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0007568| aging HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;MPO;CAT;CYP1A1 GO:0006810| transport ABCC1;SLC15A1;CACNA1I;TRPV1;ABCG2;SLC15A2;TRPV2 GO:0019430| removal of superoxide radicals MPO;SOD1 GO:0098656| SLC22A8;VDAC1;SLC22A6 GO:0006811| ion transport CHRNA7;TRPV2;SLC22A5;SLC15A2;GLRA3;SLC22A8;TRPV3;CACNA1H;TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;SLC15A1;GLRA1;TRPA1;CACNA1G GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;GPX1;CAT GO:0006855| drug transmembrane transport SLC22A5;ABCG2;ABCC1 20050:[DB14011 DB05070] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05070|ADX10059 GRM5 common genes common pathways GO:0007216| metabotropic glutamate receptor signaling pathway GRM5;DAGLA GO:0007186| G-protein coupled receptor signaling pathway GRM5;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;GPR18;PPARG GO:0007626| locomotory behavior GRM5;OPRM1;SOD1 GO:0007612| learning VDAC1;PTGS2;GRM5 GO:0007611| learning or memory CNR1;GRM5;CHRNA7 GO:0050808| synapse organization CHRNA7;GRM5 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;GRM5;OPRD1 GO:0050890| cognition GRM5;CHRNA7 GO:0051966| regulation of synaptic transmission, glutamatergic GRM5;CNR1 GO:0060078| regulation of postsynaptic membrane potential GRM5;CHRNA7 GO:0007268| synaptic transmission GRM5;OPRD1;OPRM1;GLRA3;HTR2A;CACNA1G;GLRA1;GLRB;VDAC1 20051:[DB14011 DB05481] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;SERPINA1;CAT GO:0002576| platelet degranulation SERPINA1;SOD1 20052:[DB14011 DB07596] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07596|(17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate CA2 common genes common pathways GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0001822| kidney development CAT;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 20053:[DB14011 DB08443] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08443|2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HSP90AA1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0007165| signal transduction PLA2G1B;CACNA1I;HSP90AA1;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0009408| response to heat SOD1;TRPV3;TRPV2;HSP90AA1;TRPV1 GO:0009409| response to cold TRPM8;TRPA1;PPARG;HSP90AA1 20054:[DB14011 DB14520] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:0045740| positive regulation of DNA replication PLA2G1B;CALR GO:0001895| retina homeostasis SOD1;TF GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;ITGB3 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA3;CACNA1H;TF;TRPV3;CHRNA7;TRPV2 GO:0060055| angiogenesis involved in wound healing ITGB3;GPX1 GO:0046718| entry of virus into host cell ITGB3;TFRC;HTR2A GO:0006879| cellular iron ion homeostasis TF;TFRC;SOD1;ABCG2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ITGB3 GO:0016032| viral reproduction TFRC;HTR2A;ITGB3;VDAC1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ITGB3 GO:0045892| negative regulation of transcription, DNA-dependent CALR;PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CALR;CYP1A1;PPARG GO:0007283| spermatogenesis SOD1;CNR1;CALR GO:0043277| apoptotic cell clearance ITGB3;ALOX15 GO:0010628| positive regulation of gene expression TRPV4;CALR GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;TRPV4;TRPM8;CALR GO:0032355| response to estradiol stimulus CALR;CAT;PTGS2;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;CALR;TRPA1;SMPD1;ABCC1 GO:0007155| cell adhesion ITGB3;CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;CALR;PPARG GO:0008284| positive regulation of cell proliferation CALR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0002576| platelet degranulation SOD1;TF;ITGB3 GO:0042127| regulation of cell proliferation TFRC;PTGS2;PTGS1 GO:0042060| wound healing ITGB3;ALOX15;OPRM1 20055:[DB14011 DB04991] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04991|XL784 ADAM10 common genes common pathways GO:0008284| positive regulation of cell proliferation ADAM10;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0043312| neutrophil degranulation ALOX5;CAT;ADAM10 GO:0034612| response to tumor necrosis factor PTGS2;ADAM10 20056:[DB14011 DB00025] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0007155| cell adhesion VWF;CYP1B1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;PPARG;TRPV1;TRPV4 GO:0002576| platelet degranulation SOD1;VWF GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;F2;CALR GO:0043066| negative regulation of apoptotic process HSPA5;CAT;GPX1;PROC;SOD1;PTGS2;HMGCR GO:0035722| interleukin-12-mediated signaling pathway CANX;SOD1 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0050728| negative regulation of inflammatory response CNR2;PROC GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A1;CYP2C9;PHYH;CRYZ GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;PPARG;CALR;ABCC1;SMPD1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent CALR;PPARG GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15;PHYH GO:0051260| protein homooligomerization ACAT1;VWF;GLRA3;GLRA1 GO:0006874| cellular calcium ion homeostasis CALR;TRPM8;TRPV4;GPR12;HTR2A;CHRNA7 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0007568| aging CYP1A1;LRP1;CANX;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CAT GO:0030282| bone mineralization ALOX15;PTGS2;ASGR2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0009611| response to wounding GPX1;VWF;F2;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;CALR GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;PPARG;CYP1A1;CALR GO:0045892| negative regulation of transcription, DNA-dependent CALR;PPARG GO:0010977| negative regulation of neuron projection development LRP1;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;CALR GO:0043277| apoptotic cell clearance ALOX15;LRP1 GO:0007283| spermatogenesis SOD1;CNR1;CALR GO:0042220| response to cocaine HSPA5;SMPD1;CNR1;OPRM1 GO:1990090| TRPV1;HSPA5 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;LRP1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0042953| lipoprotein transport LRP1;PPARG GO:0009314| response to radiation HSPA5;CAT;PTGS2;OPRM1 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1;ASGR2 GO:0071277| cellular response to calcium ion HSPA5;ALOX15 GO:0001889| liver development ACAT1;PROC;CYP1A1 GO:0010976| positive regulation of neuron projection development CNR1;HSPA5 GO:0010942| positive regulation of cell death PTGS2;LRP1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0043524| negative regulation of neuron apoptosis LRP1;SOD1 GO:0071320| cellular response to cAMP AANAT;HSPA5 GO:0061844| F2;PLA2G1B GO:0034976| response to endoplasmic reticulum stress HSPA5;ALOX15 GO:0055088| lipid homeostasis PPARG;ASGR2 GO:0045740| positive regulation of DNA replication CALR;PLA2G1B GO:0001523| retinoid metabolic process LRP1;NAPEPLD GO:0008283| cell proliferation HTR1A;GPX1;LRP1;CYP1A1 20057:[DB14011 DB07086] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07086|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL NCOA2;ESR1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV4;TRPV1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;NCOA2;CNR1;HMGCR GO:0007165| signal transduction ESR1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0006351| transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;ESR1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 GO:0048511| rhythmic process NCOA2;PPARG;AANAT GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0007623| circadian rhythm NCOA2;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;NCOA2;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;NCOA2;PPARG GO:0006355| regulation of transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 20058:[DB14011 DB02644] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02644|N-Omega-Propyl-L-Arginine NOS2;NOS1 common genes common pathways GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;NOS1;TRPV1 GO:0001666| response to hypoxia CAT;CHRNA7;NOS1;CYP1A1;NOS2 GO:0042311| vasodilation NOS1;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NOS1 GO:0007623| circadian rhythm AANAT;NOS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;OPRM1;CYP1A2;CNR1;IDO1;NOS2;CYP1A1 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP2C9;CYP1A1;NOS1;NOS2;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NOS1 GO:0007520| myoblast fusion NOS1;CACNA1H GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GSR;NOS1;NOS2;GPX1 GO:0033555| multicellular organismal response to stress IDO1;NOS1 GO:0006809| nitric oxide biosynthetic process NOS1;NOS2;CYP1B1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS1 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0042136| neurotransmitter biosynthetic process NOS1;DAGLA GO:0045776| negative regulation of blood pressure CNR1;NOS1;NOS2 GO:0009408| response to heat NOS1;TRPV1;SOD1;TRPV3;TRPV2 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0042738| exogenous drug catabolic process NOS1;CYP2C9;CYP2C19;CYP1A2;CYP3A4 20059:[DB14011 DB01157] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01157|Trimetrexate DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;DHFR;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 20060:[DB14011 DB07853] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07853|[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE SLK;CAMK2D;STK26 common genes common pathways GO:0010666| positive regulation of cardiac muscle cell apoptosis CAMK2D;HMGCR GO:0006915| apoptotic process STK26;GPX1;SLK;VDAC1 GO:0007399| nervous system development SMPD1;GLRB;CAMK2D GO:0042542| response to hydrogen peroxide CAT;STK26;GPX1;SOD1;TRPA1 GO:0071277| cellular response to calcium ion CAMK2D;ALOX15 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;CAMK2D GO:0008016| regulation of heart contraction CAMK2D;CACNA1H GO:0086091| CACNA1G;CAMK2D GO:0030336| negative regulation of cell migration CYP1B1;STK26 20061:[DB14011 DB05085] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05085|TM30339 NPY4R common genes common pathways GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;OPRM1;NPY4R;GLRB;VDAC1;GLRA1;CACNA1G GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;NPY4R;PLA2G1B;CACNA1I GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;GLRB;NPY4R;GLRA1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;NPY4R;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A 20062:[DB14011 DB09211] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways GO:0006955| immune response PTGER4;CNR2;OPRD1 GO:0071260| cellular response to mechanical stimulus PTGER4;PTGS2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger PTGER4;CNR1 GO:0031622| positive regulation of fever generation CNR1;PTGER3;PTGS2 GO:0071380| cellular response to prostaglandin E stimulus PTGER4;PPARG;PTGER2 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;PTGER4;CHRNA7;PTGER2;HTR2A;CNR1;GPR12;GPR55;HTR1A;PTGER3;OPRD1;CNR2;PTGER1;OPRM1 GO:0050729| positive regulation of inflammatory response TRPV4;PTGER4 GO:0050728| negative regulation of inflammatory response PTGER4;CNR2 GO:0009612| response to mechanical stimulus PPARG;PTGER4;TRPV4 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;PTGER3;OPRD1;HTR2A GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGER4;PTGER2;CNR1;OPRM1;CYP1A2;PTGER1;CNR2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PTGER2 GO:0008219| cell death PTGER3;HTR2A GO:0007186| G-protein coupled receptor signaling pathway PTGER2;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;PTGER1;OPRM1;PTGER3;OPRD1;PPARG;GPR18;PTGER4 20063:[DB14011 DB13928] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0007611| learning or memory GLP1R;CNR1;CHRNA7 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;DPP4 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0001822| kidney development CAT;MME GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043312| neutrophil degranulation MME;ALOX5;CAT GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;LPL GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG;GLP1R GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR;ALB GO:0016042| lipid catabolic process DAGLA;LPL;PLA2G1B;NAPEPLD GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1 GO:0001666| response to hypoxia CAT;CHRNA7;DPP4;CYP1A1 GO:0006644| phospholipid metabolic process PLA2G1B;LPL;NAPEPLD GO:0008016| regulation of heart contraction GLP1R;CACNA1H GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;GLP1R GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR2;PTGS2;OPRM1;MME;OPRD1;HTR2A;CNR1 GO:0009409| response to cold TRPM8;LPL;TRPA1;PPARG GO:0008152| metabolic process SMPD1;ACAT1;AMY1A GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;LPL;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0071345| cellular response to cytokine stimulus MME;TRPV1 GO:0050729| positive regulation of inflammatory response LPL;TRPV4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4;GLP1R GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;GLP1R GO:0006633| fatty acid biosynthetic process PLA2G1B;LPL;PTGS1;PTGS2 GO:0007165| signal transduction GLP1R;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7 GO:0006641| triglyceride metabolic process LPL;CAT;GPX1 GO:0006811| ion transport CACNA1H;TRPV3;SLCO1B3;GLRA3;SLCO1B1;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8 GO:0045777| positive regulation of blood pressure GLP1R;CNR1 GO:0001895| retina homeostasis ALB;SOD1 GO:0001523| retinoid metabolic process NAPEPLD;LPL GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A 20064:[DB14011 DB06771] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes CYP1A2 common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A1;CYP2C9;CRYZ GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 20065:[DB14011 DB06800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes OPRM1 common pathways GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;OPRK1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1;OPRK1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRK1;GPR18;PPARG GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0032094| response to food CYP1A1;OPRM1 GO:0043278| response to morphine OPRM1;CNR1;OPRK1 GO:0032100| positive regulation of appetite OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0042060| wound healing ALOX15;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;HTR2A GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007626| locomotory behavior OPRK1;OPRM1;SOD1 GO:0007218| neuropeptide signaling pathway GLRA1;OPRK1;GLRB;GLRA3;OPRM1;OPRD1 GO:0070848| response to growth factor stimulus OPRM1 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0032868| response to insulin stimulus OPRK1;TRPV4;CAT;AANAT GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;OPRM1 GO:0071315| cellular response to morphine OPRM1 GO:0070588| calcium ion transmembrane transport CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8;OPRM1;CACNA1H;TRPV3;TRPV2;CHRNA7 GO:0044849| OPRM1;OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0007165| signal transduction HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;OPRK1;CACNA1I;PLA2G1B GO:0007610| behavior HTR2A;HTR1A;OPRK1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;OPRK1;OPRD1;OPRM1;GLRA3;HTR2A GO:0006955| immune response OPRK1;CNR2;OPRD1 GO:0007600| sensory perception OPRK1;OPRM1;TRPV2 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain TRPA1;OPRK1;TRPV1;CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1 GO:0045471| response to ethanol OPRK1;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0009314| response to radiation OPRK1;CAT;PTGS2;OPRM1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 20066:[DB14011 DB03347] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03347|Triethyl Phosphate TP53 common genes common pathways GO:0034644| cellular response to UV PTGS2;TP53 GO:0010332| response to gamma radiation TP53;GPX1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;TP53 GO:0008283| cell proliferation HTR1A;GPX1;TP53;CYP1A1 GO:0009411| response to UV TP53;CAT GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TP53;PPARG;CYP1A1;TRPA1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;TP53 GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;TP53 GO:0006351| transcription, DNA-dependent TP53;PPARG GO:0051974| negative regulation of telomerase activity TP53;PPARG GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;TP53;SMPD1;IDO1;TRPV1;CYP1B1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TP53;HTR2A GO:0051289| protein homotetramerization CRYZ;TRPA1;TP53;TRPM8;TRPV1;CAT GO:0016032| viral reproduction HTR2A;TP53;VDAC1 GO:0071456| cellular response to hypoxia TP53;SLC29A1;OPRD1;PTGS2 GO:0007568| aging TP53;CYP1A1;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT GO:0034605| cellular response to heat PTGS2;TP53;TRPV1;TRPV4 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;TP53 GO:0006915| apoptotic process VDAC1;TP53;GPX1 GO:0043200| response to amino acid stimulus GLRB;TP53;GLRA3 GO:0048511| rhythmic process PPARG;TP53;AANAT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TP53 GO:0051262| protein tetramerization TP53;CAT;HMGCR GO:0031000| response to caffeine TP53;PPARG GO:0010628| positive regulation of gene expression TRPV4;TP53 GO:0032526| response to retinoic acid PPARG;TP53 GO:0042060| wound healing TP53;ALOX15;OPRM1 GO:0030308| negative regulation of cell growth TP53;PPARG GO:0034097| response to cytokine stimulus PTGS2;AANAT;TP53 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;TP53;PPARG GO:0046677| response to antibiotic CYP1A1;TP53;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TP53 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;TP53 GO:0007569| cell aging TP53;SOD1 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;TP53;SMPD1 GO:0006355| regulation of transcription, DNA-dependent TP53;PPARG GO:0045893| positive regulation of transcription, DNA-dependent TP53;PPARG GO:0055093| response to hyperoxia CAT;TP53;CYP1A1 GO:0010243| response to organic nitrogen TP53;TRPV1;PTGS2 20067:[DB14011 DB05146] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05146|XL820 KDR;KIT;PDGFRA;PDGFRB common genes common pathways GO:0090280| positive regulation of calcium ion import TRPV3;TRPV2;PDGFRB GO:0043627| response to estrogen stimulus PDGFRB;PPARG GO:0045740| positive regulation of DNA replication PLA2G1B;PDGFRA GO:0048146| positive regulation of fibroblast proliferation PDGFRB;PLA2G1B;PDGFRA GO:0009636| response to toxin PDGFRB;CYP1A1;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;PPARG;CYP1A1;PDGFRB;TRPA1 GO:0007165| signal transduction KIT;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;PDGFRB;GPR18 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;PDGFRA GO:0048565| digestive tract development CYP1A1;KIT GO:0008542| visual learning KIT;HMGCR GO:0006954| inflammatory response KIT;PTGS1;ALOX5;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0030217| T cell differentiation KIT;GPR18 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0016032| viral reproduction HTR2A;VDAC1;PDGFRA;KDR GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;PDGFRB;TRPA1 GO:0009314| response to radiation KIT;CAT;PTGS2;OPRM1 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;PDGFRB;SMPD1;CNR1;SOD1;PTGS2 GO:0035556| intracellular signal transduction KIT;PDGFRB;PLA2G1B GO:0001525| angiogenesis PTGS2;CYP1B1;KDR GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;PPARG GO:0043406| positive regulation of MAP kinase activity PDGFRB;KIT;HTR2A GO:0007283| spermatogenesis KIT;SOD1;CNR1 GO:0010628| positive regulation of gene expression KIT;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;PDGFRB;ALOX15;TRPV4;KDR;PDGFRA GO:0001541| ovarian follicle development KIT;SOD1 GO:0031532| actin cytoskeleton reorganization KIT;TRPV4 GO:0045766| positive regulation of angiogenesis CYP1B1;KDR;CHRNA7 GO:0000187| activation of MAPK activity SOD1;CHRNA7;KIT;PLA2G1B GO:0046686| response to cadmium ion CAT;KIT GO:0033993| response to lipid PPARG;PDGFRB GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;PDGFRA;PDGFRB;KIT;CAT GO:0035025| positive regulation of Rho protein signal transduction PDGFRB;GPR18;GPR55 GO:0007568| aging CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CYP1A1;PDGFRB GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PDGFRB;PPARG;GPR18 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;PDGFRB GO:0006687| glycosphingolipid metabolic process SMPD1;KIT GO:0061298| retina vasculature development in camera-type eye PDGFRA;CYP1B1;PDGFRB GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRB;PDGFRA;KIT;GPX1 GO:0060326| cell chemotaxis ABCC1;PDGFRB;PDGFRA;KIT GO:0055093| response to hyperoxia PDGFRB;CYP1A1;CAT GO:0048661| positive regulation of smooth muscle cell proliferation PDGFRB;PTGS2;HMGCR GO:0046427| positive regulation of JAK-STAT cascade KIT;CYP1B1 GO:0008284| positive regulation of cell proliferation PDGFRB;KDR;PDGFRA;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;KIT GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;KDR;PDGFRB GO:0032526| response to retinoic acid PPARG;PDGFRB GO:0042127| regulation of cell proliferation PTGS2;PTGS1;KIT GO:0042060| wound healing PDGFRA;ALOX15;PDGFRB;OPRM1 20068:[DB14011 DB04218] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04218|1-Deaza-Adenosine ADA common genes common pathways GO:0001889| liver development CYP1A1;ACAT1;ADA GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;ADA;GPX1 GO:0001890| placenta development PPARG;ADA;SOD1 GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0030324| lung development ADA;CYP1A2 GO:0033197| response to vitamin E ADA;CAT GO:0007155| cell adhesion ADA;CYP1B1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;ADA;GPX1 GO:0042493| response to drug CAT;ADA;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0043278| response to morphine ADA;OPRM1;CNR1 GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0007568| aging CYP1A1;ADA;CAT;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD GO:0001666| response to hypoxia CYP1A1;ADA;CHRNA7;CAT 20069:[DB14011 DB04831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04831|Tienilic acid CYP2C9 common genes CYP2C9 common pathways GO:0019627| urea metabolic process CYP2C9 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0043603| cellular amide metabolic process CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;NAAA;GPX1;PTGS1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 20070:[DB14011 DB05399] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05399|Succinobucol VCAM1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;VCAM1;CNR1;CYP1A1;IDO1 GO:0007155| cell adhesion VCAM1;CYP1B1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;VCAM1;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0060326| cell chemotaxis ABCC1;VCAM1 GO:0035094| response to nicotine VCAM1;CNR1;CHRNA7 GO:0009308| amine metabolic process VCAM1;CYP1A1 GO:0007568| aging CYP1A1;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;VCAM1;NAPEPLD GO:0071356| cellular response to tumor necrosis factor TRPV1;VCAM1 GO:0001666| response to hypoxia VCAM1;CAT;CHRNA7;CYP1A1 GO:0045471| response to ethanol CAT;OPRM1;HMGCR;VCAM1;SOD1;CNR1 GO:0016032| viral reproduction VDAC1;HTR2A;VCAM1 GO:0007584| response to nutrient PPARG;HMGCR;VCAM1;CNR1 GO:0010043| response to zinc ion VCAM1;AANAT 20071:[DB14011 DB07321] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07321|2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE FBP1 common genes common pathways GO:0008152| metabolic process SMPD1;FBP1;ACAT1 GO:0051289| protein homotetramerization CAT;FBP1;CRYZ;TRPA1;TRPM8;TRPV1 GO:0030308| negative regulation of cell growth FBP1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;PPARG;TRPV4;TRPV1 20072:[DB14011 DB02698] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport TRPV2;TTR;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0042572| retinol metabolic process CYP1B1;TTR 20073:[DB14011 DB08342] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08342|S-PALMITOYL-L-CYSTEINE TRAPPC6A;TRAPPC3;TRAPPC6B;TRAPPC5;TRAPPC4;TRAPPC1 common genes common pathways GO:0065009| regulation of molecular function TRAPPC3;TRAPPC5;TRPV1;TRAPPC4;TRAPPC1;TRAPPC6B;TRAPPC6A GO:0043312| neutrophil degranulation CAT;ALOX5;TRAPPC1 20074:[DB14011 DB02918] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02918|Zardaverine PDE4D common genes common pathways GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0006939| smooth muscle contraction HTR2A;PDE4D GO:0007165| signal transduction HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PDE4D;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4D GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;PDE4D;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0007568| aging HMGCR;PDE4D;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CAT;CYP1A1 20075:[DB14011 DB01752] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways GO:0032259| methylation PRMT3;CYP1A2;GAMT;GNMT;PNMT;PCMT1;COMTD1;SETD7;HNMT;DPH5;TRDMT1;PRMT1 GO:0008284| positive regulation of cell proliferation PRMT1;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045893| positive regulation of transcription, DNA-dependent SETD7;PPARG GO:0006355| regulation of transcription, DNA-dependent SETD7;PPARG;PRMT1;PRMT3 GO:0006936| muscle contraction GLRA1;GAMT;CACNA1H GO:0007283| spermatogenesis GAMT;SOD1;CNR1 GO:0006351| transcription, DNA-dependent PPARG;SETD7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;PRMT1;TRPA1 GO:0045471| response to ethanol SETD7;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0008152| metabolic process DPH5;SMPD1;ACAT1 GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPV1;TRPM8;GNMT;CAT GO:0040014| regulation of multicellular organism growth GAMT;SOD1 GO:0001975| response to amphetamine TRDMT1;CNR2;SOD1 GO:0007420| brain development HNMT;ACAT1 20076:[DB14011 DB08610] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08610|N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE PDK2 common genes common pathways GO:0042593| glucose homeostasis PPARG;TRPV4;PDK2;CNR1 20077:[DB14011 DB04379] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04379|N-Methyl-N-(Methylbenzyl)Formamide REN;CYP2E1 common genes common pathways GO:0006641| triglyceride metabolic process CAT;GPX1;CYP2E1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;REN GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0048469| cell maturation REN;PPARG GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CYP2E1;CAT GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0051591| response to cAMP REN;AANAT GO:0010193| response to ozone CYP2E1;CAT GO:0010033| response to organic substance TRPA1;REN;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 GO:0032496| response to lipopolysaccharide REN;CYP1A1;IDO1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0001822| kidney development REN;CAT GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0035902| response to immobilization stress PPARG;CYP1A1;REN;CYP1A2 GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;REN;ABCG2;CYP1A2;PTGS2;CYP2E1;SOD1;HTR2A;CAT GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP2E1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 20078:[DB14011 DB01970] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways GO:0033629| negative regulation of cell adhesion mediated by integrin PDE3B;CYP1B1 GO:0016525| negative regulation of angiogenesis PPARG;PDE3B GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;PDE3B GO:0001525| angiogenesis PTGS2;PDE3B;CYP1B1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1;PDE3B GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PDE3B GO:0007165| signal transduction OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;PDE3B;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I 20079:[DB14011 DB07162] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;JAK2;SMPD1 GO:0050727| regulation of inflammatory response JAK2;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;JAK2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;PPARG GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1;JAK2 GO:0043524| negative regulation of neuron apoptosis SOD1;JAK2 GO:0007165| signal transduction JAK2;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7 GO:0010811| positive regulation of cell-substrate adhesion ALOX15;JAK2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;JAK2 GO:0050729| positive regulation of inflammatory response JAK2;TRPV4 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;JAK2;PPARG GO:0006919| activation of caspase activity JAK2;PPARG GO:0045087| innate immune response PPARG;JAK2 GO:0046677| response to antibiotic SOD1;JAK2;CYP1A1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;JAK2 GO:0035722| interleukin-12-mediated signaling pathway SOD1;JAK2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;JAK2 GO:0032496| response to lipopolysaccharide CYP1A1;JAK2;IDO1;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0033194| response to hydroperoxide JAK2;GPX1 GO:0002376| immune system process JAK2;IDO1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;JAK2;PTGS2;OPRM1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;JAK2 GO:0043388| positive regulation of DNA binding PPARG;JAK2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade JAK2;CAT GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;PPARG;JAK2 GO:0034612| response to tumor necrosis factor JAK2;PTGS2 GO:0006915| apoptotic process GPX1;VDAC1;JAK2 20080:[DB14011 DB01419] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01419|Antrafenine PTGS1;PTGS2 common genes PTGS1;PTGS2 common pathways GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0010226| response to lithium ion PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS2;CNR2;ALOX5;PTGS1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;CYP2C9;PPARG;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 20081:[DB14011 DB07190] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07190|3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 20082:[DB14011 DB00887] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes PTGS2 common pathways GO:0071320| cellular response to cAMP CFTR;AANAT GO:0007268| synaptic transmission SLC12A5;GLRB;VDAC1;GLRA1;SLC12A4;CACNA1G;GLRA3;HTR2A;OPRD1;OPRM1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0016032| viral reproduction VDAC1;SLC10A1;HTR2A GO:1902476| SLC12A1;SLC12A2;GLRA3;GLRB;SLC12A5;CFTR;SLC12A4;GLRA1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:1990776| PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9 GO:0033280| response to vitamin D PTGS2 GO:0006811| ion transport GLRA1;TRPA1;SLC12A4;CFTR;CACNA1G;TRPM8;SLC12A5;SLC10A1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;SLC22A8;GLRA3;TRPV3;SLCO1A2;CACNA1H;SLC12A2;CHRNA7;SLC22A11;SLC22A7;SLC12A1;TRPV2 GO:0009636| response to toxin GPX1;CAT;SLC22A8;CYP1B1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0098656| SLC22A6;VDAC1;SLC22A8;SLC22A7 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0046718| entry of virus into host cell HTR2A;SLC10A1 GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0006821| chloride transport GLRA3;SLC12A2;SLC12A5;GLRB;GLRA1;CFTR GO:0006971| hypotonic response SLC12A5;TRPV4 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;SLC12A5;ABCG2 GO:0099133| CFTR;ABCC1 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0010042| response to manganese ion PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;IDO1 GO:0007612| learning VDAC1;SLC12A5;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0071284| cellular response to lead ion PTGS2 GO:0006695| cholesterol biosynthetic process CFTR;HMGCR GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0006884| cell volume homeostasis SLC12A4;TRPV4 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;SLC12A1;CHRNA7;GLRA3 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport TRPV2;SLC12A1;SLC22A7;SLC22A11;SLC12A2;CACNA1H;SLCO1A2;TRPV3;SLC22A8;VDAC1;TRPV4;CACNA1I;TRPV1;SLC10A1;SLC12A5;ABCG2;TRPM8;CFTR;CACNA1G;SLC22A6;ABCC1;SLC12A4;TRPA1 GO:0050891| multicellular organismal water homeostasis TRPV4;CFTR GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0097756| HMGCR;PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0006810| transport SLC10A1;TRPV1;CACNA1I;ABCG2;ABCC1;SLC12A4;TRPV2;SLC12A1;SLC12A2 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;CAT;SLC12A2;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0098869| GSR;PTGS2;CAT;PTGS1;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 20083:[DB14011 DB00756] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;GLUD1;HMGCR;CYP3A4;SOD1;SDHD;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1A1;CYP2C9;CRYZ GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TRPV1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;ESR1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 20084:[DB14011 DB04450] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04450|Heptyl 1-Thiohexopyranoside RHO;fpr;acpP common genes common pathways GO:0009416| response to light stimulus RHO;AANAT GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;PPARG;GPR18;RHO GO:0050896| response to stimulus RHO;TRPA1;TRPM8 GO:0001523| retinoid metabolic process RHO;NAPEPLD GO:0007601| visual perception RHO;GLRA1;CRYZ;GLRB;CYP1B1 GO:0007165| signal transduction PPARG;GPR18;RHO;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 20085:[DB14011 DB04000] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04000|Bromo-Willardiine GRIA2 common genes common pathways GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;GRIA2;TRPV2;CHRNA7 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;GRIA2;CHRNA7 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;GRIA2;GLRA1;CACNA1G;VDAC1;GLRB GO:0034220| ion transmembrane transport GLRA3;GRIA2;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GRIA2;GLRA1;TRPV1;GLRB 20086:[DB14011 DB03622] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03622|2-Hydroxy-5-[4-(2-Hydroxy-Ethyl)-Piperidin-1-Yl]-5-Phenyl-1h-Pyrimidine-4,6-Dione MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 20087:[DB14011 DB07626] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07626|4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0001666| response to hypoxia PLAU;CYP1A1;CAT;CHRNA7 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0043312| neutrophil degranulation ALOX5;CAT;PLAU GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;PLAU 20088:[DB14011 DB01689] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01689|Inhibitor Idd 384 AKR1B1 common genes common pathways GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0043066| negative regulation of apoptotic process AKR1B1;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0022900| electron transport chain GSR;IDO1;AKR1B1;CYP1A2 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;AKR1B1;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;AKR1B1;CYP1A2;PTGS2;SOD1 20089:[DB14011 DB09325] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;MT-CO1;CRYZ;CYP1A1;CYP2C9;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0046688| response to copper ion MT-CO1;AANAT;SOD1 GO:0007568| aging CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;MT-CO1 GO:0009060| aerobic respiration CAT;MT-CO1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;MT-CO1 20090:[DB14011 DB00115] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0015889| cobalamin transport AMN;TCN2;CUBN;GIF;ABCC1;TCN1 GO:0009791| post-embryonic development CYP1A2;MUT GO:0006749| glutathione metabolic process SOD1;GPX1;MMACHC;GSR GO:0006811| ion transport GLRA3;TCN2;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;GLRA1;GIF;CACNA1G;TCN1;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1 GO:0007399| nervous system development MTR;GLRB;SMPD1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CUBN;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG GO:0042953| lipoprotein transport CUBN;PPARG GO:0008152| metabolic process ACAT1;MTHFR;SMPD1;MUT GO:0048678| response to axon injury MTR;SOD1 GO:0070988| demethylation CYP1A1;MMACHC GO:0009235| cobalamin metabolic process ABCC1;MMAB;MUT;GIF;MMAA;MMACHC;TCN1;TCN2;AMN;MTRR;CUBN;MTR GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CUBN;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4;CUBN GO:0001666| response to hypoxia CHRNA7;CAT;MTHFR;CYP1A1 GO:0043200| response to amino acid stimulus GLRA3;MTHFR;GLRB GO:0043312| neutrophil degranulation ALOX5;CAT;TCN1 GO:0032259| methylation MTR;MTRR;CYP1A2 GO:0008203| cholesterol metabolic process CAT;CUBN;HMGCR GO:0055114| oxidation-reduction process MMACHC;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;MTRR;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;MTHFR;CYP3A7;PTGS2;CYP1A2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CAT;MTHFR;PTGS2;CYP1A2;HTR2A;SOD1 20091:[DB14011 DB08257] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways GO:0008152| metabolic process EPHX2;ACAT1;SMPD1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;EPHX2;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;PTGS1;NAAA;GPX1;EPHX2;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS1;ALOX5;PTGS2;CNR2;EPHX2 GO:0072593| reactive oxygen species metabolic process SOD1;EPHX2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;EPHX2;PTGS2 GO:0009636| response to toxin GPX1;CAT;EPHX2;CYP1B1;CYP1A1 GO:0019373| epoxygenase P450 pathway EPHX2;CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0006874| cellular calcium ion homeostasis EPHX2;HTR2A;GPR12;CHRNA7;TRPM8;TRPV4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;EPHX2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0010628| positive regulation of gene expression TRPV4;EPHX2 20092:[DB14011 DB04721] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04721|N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;CSNK2A1;HMGCR;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent PPARG;CSNK2A1 GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG GO:0006915| apoptotic process CSNK2A1;GPX1;VDAC1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CSNK2A1;PTGS2 GO:0007165| signal transduction GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;CSNK2A1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B 20093:[DB14011 DB07991] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;ESR1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ESR1;HTR2A;OPRM1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;ESR1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 20094:[DB14011 DB06635] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06635|Otamixaban F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 20095:[DB14011 DB05298] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05298|Tetomilast PDE4D common genes common pathways GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4D GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;PDE4D;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0007568| aging CAT;CNR1;SOD1;HTR2A;NAPEPLD;PDE4D;HMGCR;PTGS2;CYP1A1 GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;PDE4D;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 20096:[DB14011 DB03328] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03328|dioxothiomolybdenum(VI) ion XDH common genes common pathways GO:0006919| activation of caspase activity PPARG;XDH GO:0007595| lactation XDH;SLC29A1 GO:0010629| negative regulation of gene expression XDH;OPRD1 GO:0006195| purine nucleotide catabolic process GPX1;XDH GO:0022900| electron transport chain GSR;IDO1;CYP1A2;XDH GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;XDH;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT 20097:[DB14011 DB07030] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07030|(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;AKR1B1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;AKR1B1;SOD1;CYP1A2;PTGS2 20098:[DB14011 DB04339] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04339|Carbocisteine GSTP1 common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0034599| cellular response to oxidative stress GPX1;CAT;SOD1;GSTP1;GSR GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1;GSTP1 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0043200| response to amino acid stimulus GLRB;GSTP1;GLRA3 GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSTP1;GSR GO:0032720| negative regulation of tumor necrosis factor production GSTP1;GPR18;CHRNA7 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;GSTP1 GO:1904706| PPARG;GSTP1 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C19;CYP1B1;GSTP1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2 GO:0008152| metabolic process GSTP1;SMPD1;ACAT1 GO:0045471| response to ethanol GSTP1;OPRM1;HMGCR;CNR1;SOD1;CAT GO:0032930| positive regulation of superoxide anion generation SOD1;GSTP1 GO:0006749| glutathione metabolic process GSTP1;GSR;GPX1;SOD1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0009636| response to toxin CAT;GPX1;CYP1B1;GSTP1;CYP1A1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B 20099:[DB14011 DB05101] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05101|Matuzumab EGFR common genes common pathways GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0001503| ossification ALOX15;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0007166| cell surface receptor linked signaling pathway TRPV1;EGFR;TRPA1 GO:0051592| response to calcium ion AANAT;EGFR GO:0001889| liver development CYP1A1;EGFR;ACAT1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;EGFR GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;EGFR GO:0007165| signal transduction EGFR;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2;OPRD1 GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response EGFR;TRPV4 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;EGFR GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0008283| cell proliferation GPX1;HTR1A;EGFR;CYP1A1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;EGFR GO:0043066| negative regulation of apoptotic process EGFR;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0042060| wound healing OPRM1;ALOX15;EGFR GO:0042127| regulation of cell proliferation PTGS1;PTGS2;EGFR GO:0007623| circadian rhythm AANAT;EGFR GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0030324| lung development CYP1A2;EGFR GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;EGFR GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1;EGFR GO:0033993| response to lipid EGFR;PPARG GO:0032355| response to estradiol stimulus EGFR;PTGS2;CYP1A2;CAT GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;CAT;OPRD1 GO:0007202| activation of phospholipase C activity EGFR;HTR2A;GPR55 GO:0043406| positive regulation of MAP kinase activity HTR2A;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;EGFR;ALOX15 20100:[DB14011 DB07242] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07242|(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile DAPK3;PIM1 common genes common pathways GO:0008283| cell proliferation PIM1;HTR1A;GPX1;CYP1A1 GO:0006351| transcription, DNA-dependent DAPK3;PPARG GO:0035556| intracellular signal transduction PLA2G1B;DAPK3 GO:0043065| positive regulation of apoptotic process DAPK3;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0006915| apoptotic process VDAC1;PIM1;DAPK3;GPX1 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0006355| regulation of transcription, DNA-dependent DAPK3;PPARG 20101:[DB14011 DB07508] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07508|4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 20102:[DB14011 DB06454] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes HTR1A common pathways GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0009636| response to toxin CYP1A1;CYP1B1;DRD2;CAT;GPX1 GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A GO:0014854| response to inactivity CAT;DRD2 GO:0042053| regulation of dopamine metabolic process HTR1A GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0001662| behavioral fear response HTR1A;VDAC1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;DRD2;CYP1B1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;DRD3;CYP1A1;PPARG GO:0040014| regulation of multicellular organism growth SOD1;DRD3 GO:0001975| response to amphetamine DRD2;DRD3;CNR2;SOD1 GO:0050482| arachidonic acid secretion DRD3;PLA2G1B;DRD2 GO:1900273| CHRNA7;DRD2 GO:0007165| signal transduction GPR18;DRD3;PPARG;SMPD1;PLA2G1B;CACNA1I;DRD2;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7 GO:0007610| behavior HTR1A;HTR2A GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0001964| startle response GLRB;DRD2;GLRA1 GO:0008542| visual learning HMGCR;DRD3;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0045776| negative regulation of blood pressure CNR1;DRD3;DRD2 GO:0045471| response to ethanol DRD3;DRD2;SOD1;CNR1;HMGCR;OPRM1;CAT GO:0048678| response to axon injury DRD2;SOD1 GO:0001659| temperature homeostasis HTR2A;GPX1;DRD2;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0042310| vasoconstriction HTR1A GO:0035556| intracellular signal transduction PLA2G1B;DRD2 GO:0048148| behavioral response to cocaine HTR2A;DRD3;DRD2 GO:0042428| serotonin metabolic process HTR1A GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0014062| regulation of serotonin secretion HTR1A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;DRD2;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0042220| response to cocaine CNR1;OPRM1;DRD2;DRD3;SMPD1 GO:0001666| response to hypoxia CYP1A1;DRD2;CAT;CHRNA7 GO:0009416| response to light stimulus AANAT;DRD2 GO:0014059| regulation of dopamine secretion HTR2A;DRD3;DRD2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;DRD2;GPR55 GO:0051209| release of sequestered calcium ion into cytosol DRD2;TRPV1;TRPA1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;DRD3;GPR18;PPARG;DRD2 GO:0006874| cellular calcium ion homeostasis DRD3;TRPV4;DRD2;TRPM8;HTR2A;GPR12;CHRNA7 GO:0007210| serotonin receptor signaling pathway HTR1A;HTR2A GO:0042493| response to drug DRD2;ABCG2;ABCC1;SMPD1;DRD3;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0035640| exploration behavior HTR1A GO:0043278| response to morphine CNR1;OPRM1;DRD2;DRD3 GO:0035094| response to nicotine DRD2;CHRNA7;CNR1 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0007612| learning PTGS2;DRD3;VDAC1 GO:0007611| learning or memory CNR1;CHRNA7;DRD3 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;GLRB;DRD2;TRPV1;GLRA1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0007626| locomotory behavior DRD2;DRD3;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;DRD2;DRD3;PPARG GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;DRD3 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD3 GO:0007628| adult walking behavior GLRA1;DRD2;GLRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;DRD3;TRPV4;TRPV1 GO:0050795| regulation of behavior HTR2A;HTR1A GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 20103:[DB14011 DB14126] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14126|Tenofovir ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0006810| transport TRPV2;ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;CACNA1I;ABCB1;TRPV4;VDAC1;TRPA1;CACNA1G;ABCC1 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCB1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT 20104:[DB14011 DB08389] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PDE10A;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;PDE10A;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0008152| metabolic process SMPD1;PDE10A;ACAT1 20105:[DB14011 DB00677] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0006879| cellular iron ion homeostasis TF;SOD1;ABCG2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0001895| retina homeostasis TF;SOD1;ALB GO:0008283| cell proliferation GPX1;ACHE;HTR1A;CYP1A1 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;TF;GLRA3;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0008285| negative regulation of cell proliferation CYP1B1;BCHE;PPARG;OPRM1;PTGS2 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0007155| cell adhesion ACHE;CYP1B1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0002576| platelet degranulation TF;SOD1;ALB GO:0007517| muscle organ development CACNA1H;ACHE GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;BCHE GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0098869| GSR;ALB;GPX1;PTGS1;CAT;PTGS2 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization HMGCR;ACHE;CAT 20106:[DB14011 DB05806] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05806|Cositecan TOP1 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A;VDAC1 GO:0048511| rhythmic process PPARG;TOP1;AANAT GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;TOP1;CAT;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0007623| circadian rhythm AANAT;TOP1 20107:[DB14011 DB04633] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways GO:0001525| angiogenesis PTGS2;SAT1;CYP1B1 GO:0042127| regulation of cell proliferation PTGS2;SAT1;PTGS1 20108:[DB14011 DB13926] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13926|Cenegermin NTRK1 common genes common pathways GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;NTRK1;OPRM1;PTGS2 GO:1990090| NTRK1;TRPV1 GO:0007399| nervous system development GLRB;NTRK1;SMPD1 GO:0009314| response to radiation CAT;OPRM1;PTGS2;NTRK1 GO:0048678| response to axon injury NTRK1;SOD1 GO:0019233| sensory perception of pain TRPV1;TRPA1;NTRK1;PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1;NTRK1 GO:0010976| positive regulation of neuron projection development NTRK1;CNR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NTRK1;PLA2G1B;CAT GO:0001934| positive regulation of protein phosphorylation CHRNA7;NTRK1 GO:0031667| response to nutrient levels SOD1;NTRK1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;NTRK1;TRPA1 GO:0043524| negative regulation of neuron apoptosis SOD1;NTRK1 GO:0007568| aging NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT;CYP1A1;NTRK1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;NTRK1;TRPV1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;NTRK1 GO:0045766| positive regulation of angiogenesis NTRK1;CYP1B1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4;NTRK1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;NTRK1 GO:0007611| learning or memory CHRNA7;CNR1;NTRK1 GO:0007623| circadian rhythm NTRK1;AANAT GO:0035094| response to nicotine NTRK1;CHRNA7;CNR1 GO:0042493| response to drug TRPA1;NTRK1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT 20109:[DB14011 DB11323] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0098869| GSR;PTGS2;CAT;GPX1;PTGS1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0046697| decidualization PTGS2 GO:0007568| aging CAT;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;CYP1A1;PPARG GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0071284| cellular response to lead ion PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:1990776| PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1;TRPA1;TRPV1 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS1;ALOX5;CNR2;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 20110:[DB14011 DB03957] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03957|SP2456 IL2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;PPARG;IL2 GO:0002376| immune system process IL2;IDO1 GO:0050728| negative regulation of inflammatory response CNR2;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;IL2;PLA2G1B GO:0008284| positive regulation of cell proliferation IL2;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;IL2 GO:0007155| cell adhesion IL2;CYP1B1 GO:0050729| positive regulation of inflammatory response IL2;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;IL2 GO:0065009| regulation of molecular function IL2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;IL2 GO:0030217| T cell differentiation IL2;GPR18 GO:0006955| immune response IL2;OPRD1;CNR2 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;IL2 20111:[DB14011 DB14544] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes CYP3A4;CYP3A5;CYP3A7;ABCG2 common pathways GO:0070301| cellular response to hydrogen peroxide ANXA1;CYP1B1 GO:0046883| regulation of hormone secretion HTR1A;HTR2A;ANXA1 GO:0070365| hepatocyte differentiation CYP1A1;ANXA1 GO:0035865| cellular response to potassium ion SOD1;CACNA1H;CYP11B1;CYP11B2 GO:0008217| regulation of blood pressure PTGS1;CYP11B1;PTGS2;SOD1;PPARG GO:0098656| SLC22A8;VDAC1 GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;CACNA1H;SLCO1A2;TRPV3;SLC22A8;GLRA3 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;ANXA1;PPARG;CYP1A1;TRPA1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;GPX1;CAT GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0032868| response to insulin stimulus AANAT;CAT;TRPV4;HSD11B2 GO:0006702| androgen biosynthetic process CYP17A1;HSD3B1 GO:0031394| positive regulation of prostaglandin biosynthetic process ANXA1;PTGS2 GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0044849| ANXA1;OPRM1 GO:0032870| cellular response to hormone stimulus CACNA1H;CYP11B1;CYP11B2 GO:0050482| arachidonic acid secretion ANXA1;PLA2G1B GO:0009725| response to hormone stimulus ACAT1;ANXA1 GO:0097267| CYP2C19;CYP2C8;CYP1B1;CYP2C9;CYP1A1;CYP1A2 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;NR3C1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;ANXA1 GO:1900087| ANXA1;CYP1A1 GO:0051384| response to glucocorticoid stimulus HSD11B2;ANXA1;PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0043434| response to peptide hormone stimulus TRPV1;ANXA1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0034651| cortisol biosynthetic process CACNA1H;CYP11B2;CYP11B1 GO:0006954| inflammatory response TRPV1;ANXA1;ALOX15;IDO1;PTGS1;ALOX5;PTGS2;CNR2 GO:0006955| immune response CYP11B1;OPRD1;CNR2 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;PTGS2 GO:0007565| female pregnancy IDO1;HSD11B2 GO:0046415| urate metabolic process ABCG2 GO:0050727| regulation of inflammatory response ANXA1;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;ANXA1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0016125| sterol metabolic process CYP11B2;CYP11B1;CYP1B1;CYP17A1 GO:0008152| metabolic process HSD3B1;SMPD1;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP11B2;CYP11B1;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ANXA1 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0001666| response to hypoxia HSD11B2;CYP1A1;CAT;CHRNA7 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1;ANXA1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5;CYP2C8 GO:0036378| CYP3A4 GO:0055085| transmembrane transport ABCG2;TRPM8;VDAC1;TRPV4;ABCB1;CACNA1I;TRPV1;TRPA1;CACNA1G;ABCC1;TRPV2;SLC22A8;CACNA1H;SLCO1A2;TRPV3 GO:0031532| actin cytoskeleton reorganization ANXA1;TRPV4 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0002376| immune system process IDO1;ANXA1 GO:0042593| glucose homeostasis CNR1;CYP11B1;TRPV4;PPARG GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0006704| glucocorticoid biosynthetic process CYP11B1;HSD3B1;HSD11B2;CYP17A1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;ANXA1;PPARG;GPR18 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;ANXA1 GO:0008202| steroid metabolic process CYP17A1;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CYP3A4;CYP1A2;CYP3A7;CYP11B2;HMGCR;CYP11B1 GO:0006810| transport ABCC1;ABCG2;TRPV1;ABCB1;CACNA1I;TRPV2 GO:0006694| steroid biosynthetic process CYP11B1;CYP11B2;HMGCR;CYP17A1;HSD3B1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0015886| heme transport ABCG2 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0042493| response to drug ABCG2;ANXA1;HSD11B2;ABCB1;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0032094| response to food OPRM1;HSD11B2;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP11B2;CYP11B1;CAT;GPX1;ALOX5;PTGS1;CYP2C9;CYP1A1;CRYZ;HSD3B1;HSD11B2;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2C8;CYP2D6;CYP1B1 GO:0032342| aldosterone biosynthetic process CACNA1H;CYP11B2;CYP11B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ANXA1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2C8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;TRPV4;TRPV1 GO:0045087| innate immune response ANXA1;PPARG GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ANXA1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0033344| cholesterol efflux ABCG2 20112:[DB14011 DB14481] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes CACNA1I;CACNA1G;CACNA1H common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CALR GO:0031000| response to caffeine RYR2;PPARG;RYR1 GO:0051262| protein tetramerization TRPV5;HMGCR;CAT GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;NRXN1 GO:0010033| response to organic substance SOD1;CASQ1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1;CALR GO:0071356| cellular response to tumor necrosis factor TRPV1;CIB1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;NRXN1 GO:0048741| skeletal muscle fiber development GPX1;RYR1 GO:0007283| spermatogenesis CATSPER1;CALR;CIB1;CNR1;SOD1;CALR3;RGN GO:0010628| positive regulation of gene expression CASR;TRPV4;CALR GO:0046688| response to copper ion S100A13;AANAT;SOD1 GO:0010977| negative regulation of neuron projection development TRPV4;CIB1 GO:0001666| response to hypoxia CYP1A1;RYR2;RYR1;SLC8A1;CHRNA7;CAT GO:0045766| positive regulation of angiogenesis CHRNA7;PDCD6;CYP1B1 GO:0008219| cell death CACNA1A;HTR2A GO:0006915| apoptotic process CASR;GPX1;CIB1;PDCD6;VDAC1 GO:0055085| transmembrane transport SLC8A1;CACNA1D;TRPV2;SLC34A3;RYR1;CACNA1C;CALM1;SLC20A2;CACNA1H;TRPV3;SLC20A1;TRPV4;CACNA1I;VDAC1;CACNA1A;TRPV1;RYR2;SLC34A2;CACNA1F;ABCG2;TRPM8;TRPV5;CACNA1S;CATSPER1;CACNA1G;ABCC1;RYR3;CACNA1E;TRPV6;TRPA1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;CIB1;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0086002| CACNA1G;CACNA1C;CACNA1D GO:0034220| ion transmembrane transport CASQ1;GLRA3;RYR1;S100A6;CHRNA7;RYR3;GLRA1;TRPA1;GLRB;TRPV1;RYR2;CASQ2 GO:0051591| response to cAMP AANAT;SPARC GO:0046686| response to cadmium ion SLC34A1;SPARC;CAT GO:0043085| positive regulation of catalytic activity SOD1;CIB1 GO:0007605| sensory perception of sound SOD1;CACNA1D;GPX1 GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;CACNA1H GO:0006936| muscle contraction CACNA1S;GLRA1;CACNA1H;RYR1;SLC8A1;CALM1 GO:0098869| ALB;GSR;CAT;GPX1;PTGS1;PTGS2 GO:0006874| cellular calcium ion homeostasis TRPV4;RYR2;TRPM8;RYR3;CALR;SLC8A1;RYR1;CASR;CHRNA7;RGN;TPT1;HTR2A;GPR12 GO:1901214| CHP1;CHRNA7 GO:0051260| protein homooligomerization GLRA1;ACAT1;SLC34A1;GLRA3 GO:0006810| transport TRPV1;CACNA1I;ABCG2;CACNB1;CACNA1E;ABCC1;CACNB3;TRPV2;CACNB4;SLC20A2;SRI;SLC20A1 GO:0007568| aging CANX;CYP1A1;CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;RGN GO:0007635| chemosensory behavior CASR;TRPV1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC8A1;S100B;SLC29A1;CASR GO:0034605| cellular response to heat PDCD6;TRPV4;TRPV1;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway CALM3;CASR;CALM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;CALM2;PPARG GO:0086027| CACNA1G GO:0086018| CACNA1G GO:0071363| cellular response to growth factor stimulus TRPV1;CIB1;OPRD1;CAT;SPARC GO:0051209| release of sequestered calcium ion into cytosol RYR1;HTR2A;RYR2;TRPV1;TRPA1;RYR3 GO:0071468| cellular response to acidity PKD2L1;TRPV1;CHP1;PKD1L3 GO:0032355| response to estradiol stimulus CALR;CYP1A2;PTGS2;CAT;SLC34A1 GO:0016525| negative regulation of angiogenesis PPARG;SPARC GO:0033189| response to vitamin A CAT;SLC34A1;CYP1A1;PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus CASR;PPARG GO:0032342| aldosterone biosynthetic process CACNA1H GO:0007517| muscle organ development SRI;CACNA1H GO:0006355| regulation of transcription, DNA-dependent PPARG;CALR GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CALR;SLC34A1;SLC8A1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0035902| response to immobilization stress SLC8A1;CYP1A2;PPARG;CYP1A1 GO:0043312| neutrophil degranulation GCA;ALOX5;CAT GO:0035307| positive regulation of protein dephosphorylation CALM1;CALM3;SMPD1;CALM2 GO:0010288| response to lead ion SPARC;CAT;SLC34A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter CALR;PPARG;TRPV4;TRPV1 GO:0007155| cell adhesion CYP1B1;CIB1;NRXN1 GO:0045087| innate immune response PPARG;S100B GO:0034097| response to cytokine stimulus PTGS2;AANAT;SPARC GO:0035722| interleukin-12-mediated signaling pathway CANX;SOD1 GO:0043066| negative regulation of apoptotic process ALB;CIB1;SOD1;TPT1;RGN;HMGCR;PTGS2;CAT;GPX1 GO:0001822| kidney development RGN;CAT;PKD1L3;SLC34A1 GO:0042311| vasodilation CASR;GPX1 GO:0086015| CACNA1G GO:0008284| positive regulation of cell proliferation CHRNA7;S100A13;CASR;S100B;HTR2A;HTR1A;HMGCR;PTGS2;CIB1;CALR GO:0007626| locomotory behavior OPRM1;SOD1;CALB1 GO:0010045| response to nickel cation CACNA1G GO:0009615| response to virus CYP1A1;TPT1 GO:0002576| platelet degranulation SOD1;SPARC;CALM1;ALB GO:0070207| protein homotrimerization TRPM8;PKD2L1 GO:0007269| neurotransmitter secretion NRXN1;NAAA GO:0071333| cellular response to glucose stimulus CASR;SLC29A1 GO:0030317| sperm motility CATSPER1;CACNA1I GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;SLC8A1;RYR3 GO:0070509| calcium ion import CACNA1H;CACNB2;SLC8A1;CACNA1D;CASR;CACNA1G;TRPV4;CACNA1I GO:0007614| short-term memory CALB1;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CASR;HTR2A;OPRM1;OPRD1 GO:0086016| CACNA1G GO:0030324| lung development CYP1A2;SPARC GO:0007611| learning or memory CHRNA7;S100B;CNR1;CALB1 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1;CIB2;RYR3 GO:0001508| regulation of action potential SRI;CACNA1G;GLRA1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;SPARC;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0042127| regulation of cell proliferation CIB1;SPARC;PTGS1;PTGS2 GO:0042060| wound healing SPARC;OPRM1;ALOX15 GO:0007612| learning VDAC1;NRXN1;PTGS2 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0008285| negative regulation of cell proliferation PPARG;CIB1;CYP1B1;OPRM1;PTGS2 GO:0086046| CACNA1G;CACNA1D GO:0007584| response to nutrient HMGCR;CNR1;SLC8A1;SLC34A1;PPARG GO:0006812| cation transport PKD1L3;PKD2L1;TRPM8 GO:0043627| response to estrogen stimulus SLC34A2;PPARG GO:0090280| positive regulation of calcium ion import CASR;TRPV2;TRPV3 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;S100A6 GO:0045740| positive regulation of DNA replication PLA2G1B;CALR GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G GO:0050896| response to stimulus TRPM8;CACNA1F;TRPA1 GO:0001895| retina homeostasis ALB;SOD1 GO:0033591| response to L-ascorbic acid SPARC;CAT GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;CASR;AANAT;ACAT1 GO:0043267| negative regulation of potassium ion transport HTR2A;CASQ2 GO:0006919| activation of caspase activity PDCD6;PPARG GO:0086045| CACNB2;CACNA1C;CACNA1G GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1;CHP1 GO:0008283| cell proliferation GPX1;S100B;HTR1A;CYP1A1 GO:0006811| ion transport TRPV6;CACNB3;GLRA1;TRPA1;CACNA1G;PKD2L1;CATSPER1;CACNA1S;TRPV5;RYR3;CACNA1E;CACNB1;TRPM8;CACNA1A;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;RYR2;CACNA1F;SLC34A2;CACNB2;SLC20A1;GLRA3;CACNA1H;TRPV3;SLC20A2;PKD1L3;CHRNA7;CACNA1D;SLC8A1;SLC34A3;CACNB4;TRPV2;RYR1;SLC34A1;CACNA1C GO:0065009| regulation of molecular function NRXN1;TRPV1 GO:0045019| negative regulation of nitric oxide biosynthetic process RGN;OPRM1 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1I;CACNA1G;CACNA1H GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;HTR1A;SLC20A1;GPR55;OPRD1;SRI;OPRM1;CNR2;CHRNA7;S100A6;SPARC;CASR GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0043010| camera-type eye development CYP1A1;FBN2;CACNA1C GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;CASR GO:1904645| CACNA1A;CHRNA7 GO:0032870| cellular response to hormone stimulus CACNA1H GO:0070588| calcium ion transmembrane transport CACNB1;TRPM8;TRPV1;CACNA1I;TRPV4;CACNA1A;CACNA1F;RYR2;TRPV6;TRPA1;CACNB3;TRPV5;CACNA1S;CATSPER1;PKD2L1;CACNA1G;CACNA1E;RYR3;CHRNA7;PKD1L3;TRPV2;CACNB4;SLC8A1;CACNA1D;CACNA1C;NCS1;RYR1;CACNB2;CACNA1H;OPRM1;TRPV3 GO:0034765| regulation of ion transmembrane transport CACNA1E;CACNA1G;CACNA1S;CATSPER1;CACNB3;CACNA1F;CACNA1A;CACNA1I;CACNB1;CACNA1H;CACNB2;CACNA1C;CACNA1D;CACNB4 GO:0007601| visual perception CACNA1F;GLRB;CYP1B1;GLRA1;CRYZ;CACNB2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;CASR GO:0007204| elevation of cytosolic calcium ion concentration CACNA1C;SLC8A1;OPRM1;HTR2A;CACNA1A;TRPV4;TRPV1;CIB2 GO:0050796| regulation of insulin secretion CACNA1A;CACNA1E;CACNA1D;CACNA1C;CNR1 GO:0007613| memory S100B;CHRNA7;PTGS2;CNR1;HTR2A GO:0007520| myoblast fusion CACNA1H GO:0043434| response to peptide hormone stimulus SLC34A1;SPARC;TRPV1 GO:0046718| entry of virus into host cell HTR2A;SLC20A2 GO:0051384| response to glucocorticoid stimulus PTGS2;S100B;SPARC GO:0086010| CACNA1H;CACNA1S;CATSPER1;CACNA1G;CACNA1E;CACNA1I;CACNA1A;CACNA1F GO:0051924| regulation of calcium ion transport SLC8A1;CASR;SRI;OPRD1 GO:0016032| viral reproduction SLC20A2;HTR2A;VDAC1 GO:0006816| calcium ion transport TRPA1;CACNB3;TRPV6;RYR3;CACNA1E;TRPV5;CATSPER1;CACNA1S;PKD2L1;CACNA1G;TRPM8;CACNB1;RYR2;CACNA1F;CACNA1I;TRPV4;CACNA1A;TRPV1;TPT1;CACNB2;SRI;TRPV3;CACNA1H;PKD1L3;CHRNA7;CASR;RYR1;CACNA1C;SLC8A1;CACNA1D;TRPV2;CACNB4 GO:0034651| cortisol biosynthetic process CACNA1H GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;CIB1 GO:0009408| response to heat TRPV1;SOD1;CASQ1;TRPV3;TRPV2 GO:0051289| protein homotetramerization RYR1;CAT;RYR3;CRYZ;TRPA1;TRPV1;TRPM8 GO:0001934| positive regulation of protein phosphorylation CHRNA7;CIB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;CIB1 GO:0098703| TRPV5;TRPV6;TRPV1 GO:0071320| cellular response to cAMP AANAT;SLC8A1 GO:0007268| synaptic transmission OPRM1;OPRD1;NRXN1;CACNB2;HTR2A;GLRA3;CACNB4;CACNA1G;CACNA1E;GLRA1;CACNB3;GLRB;VDAC1;CACNB1 GO:0060078| regulation of postsynaptic membrane potential SLC8A1;CHRNA7 GO:0002027| regulation of heart rate CALM1;CALM3;SLC8A1;CASQ2;RYR2;CALM2;CACNA1G GO:1990090| CIB1;TRPV1 GO:0001503| ossification ALOX15;SPARC;CASR;SLC34A1 GO:0007507| heart development PPARG;CACNA1C;SPARC;SRI GO:0035556| intracellular signal transduction CAPS;PLA2G1B GO:0042542| response to hydrogen peroxide TRPA1;SLC8A1;GPX1;CAT;SOD1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CACNA1D GO:0043065| positive regulation of apoptotic process S100B;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0001889| liver development CYP1A1;RGN;ACAT1 GO:0035725| sodium ion transmembrane transport CACNA1H;SLC20A1;SLC8A1;SLC34A3;SLC34A1;SLC20A2;PKD2L1;CACNA1G;CACNA1I;SLC34A2 GO:0030431| sleep HTR2A;SLC29A1;CACNA1I GO:0051592| response to calcium ion PDCD6;S100A16;TRPV6;CALM2;SPARC;CALM1;CASR;AANAT;CALM3;PEF1 GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;CACNA1H GO:0098662| CACNA1H GO:0071277| cellular response to calcium ion RYR1;RYR3;ALOX15 GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;SPARC;CAT GO:0001525| angiogenesis PTGS2;CYP1B1;CIB1;PDCD6 GO:0008016| regulation of heart contraction SRI;CACNA1H GO:0086091| CACNB2;CACNA1D;CACNA1C;CACNA1G 20113:[DB14011 DB06401] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06401|Bazedoxifene ESR1;ESR2;UGT1A8;UGT1A10 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0008152| metabolic process UGT1A8;SMPD1;UGT1A10;ACAT1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG GO:0006351| transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0007165| signal transduction OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;ESR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;ESR2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;ESR1;HTR2A GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2;ESR1 GO:0009804| coumarin metabolic process CYP2D6;UGT1A8;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0006631| fatty acid metabolic process ALOX15;UGT1A8;PTGS1;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;TRPV1;TRPV4;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ESR2;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;UGT1A8;CYP3A4;UGT1A10;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;ESR1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;ESR1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;UGT1A8;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR 20114:[DB14011 DB08102] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways GO:0006810| transport TRPV2;TTR;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process CYP1B1;TTR 20115:[DB14011 DB08030] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08030|3-[(4'-cyanobiphenyl-4-yl)oxy]-N-hydroxypropanamide MMP3 common genes common pathways 20116:[DB14011 DB07020] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;MAPK9 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1;MAPK9 GO:0042752| regulation of circadian rhythm PPARG;MAPK9 GO:0046686| response to cadmium ion MAPK9;CAT GO:0048511| rhythmic process MAPK9;AANAT;PPARG GO:0010628| positive regulation of gene expression TRPV4;MAPK9 GO:0009612| response to mechanical stimulus MAPK9;TRPV4;PPARG 20117:[DB14011 DB05739] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;OPRM1;AGTR1 GO:0050729| positive regulation of inflammatory response TRPV4;AGTR1 GO:0007165| signal transduction AGTR2;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;AGTR1;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0007420| brain development ACAT1;AGTR2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;AGTR2 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;AGTR2 GO:0007166| cell surface receptor linked signaling pathway AGTR2;TRPV1;TRPA1 GO:0035556| intracellular signal transduction AGTR2;PLA2G1B GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0006954| inflammatory response ALOX15;IDO1;AGTR2;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0007186| G-protein coupled receptor signaling pathway AGTR2;PPARG;GPR18;AGTR1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;AGTR2;OPRM1;PTGS2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger AGTR1;GPR55;GPR18 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGTR1;HTR2A;OPRD1;OPRM1 GO:0030308| negative regulation of cell growth PPARG;AGTR2 GO:0042127| regulation of cell proliferation PTGS2;AGTR1;PTGS1 GO:0042311| vasodilation GPX1;AGTR2 GO:0001822| kidney development AGTR2;CAT;AGTR1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;AGTR2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AGTR2 GO:0060326| cell chemotaxis AGTR1;ABCC1 GO:0035640| exploration behavior AGTR2;HTR1A GO:0010243| response to organic nitrogen PTGS2;TRPV1;AGTR2 20118:[DB14011 DB05966] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05966|TAS-108 ESR1;ESR2 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 GO:0032355| response to estradiol stimulus CAT;ESR1;CYP1A2;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;ESR2;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;ESR2;PLA2G1B GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;ESR2;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;ESR1;OPRD1;OPRM1;CNR2;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG;ESR2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 20119:[DB14011 DB00017] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00017|Salmon Calcitonin CALCR common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;CALCR GO:0007165| signal transduction CACNA1I;PLA2G1B;CALCR;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0051384| response to glucocorticoid stimulus PTGS2;CALCR GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;CALCR;TRPV4;TRPV1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;CALCR;TRPA1 GO:0010942| positive regulation of cell death CALCR;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CALCR;GPR18;PPARG GO:0007202| activation of phospholipase C activity CALCR;GPR55;HTR2A GO:0010628| positive regulation of gene expression CALCR;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15;CALCR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;CALCR 20120:[DB14011 DB07741] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07741|4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 20121:[DB14011 DB04200] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04200|Matairesinol DHRS4L2 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP3A4;DHRS4L2;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 20122:[DB14011 DB08263] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08263|N-(carboxycarbonyl)-D-phenylalanine HIF1AN common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1;CYP2C9;CYP1A1;CRYZ;HIF1AN;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 GO:0006355| regulation of transcription, DNA-dependent HIF1AN;PPARG GO:0006351| transcription, DNA-dependent PPARG;HIF1AN 20123:[DB14011 DB05266] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;PDE3A GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;PPARG;CYP1A1;TRPA1;PDE3A;ABCC1;SMPD1 GO:0030593| neutrophil chemotaxis PDE4D;PDE4B;PLA2G1B GO:0007186| G-protein coupled receptor signaling pathway PDE4C;PDE4B;GPR18;PPARG;PDE3A;HTR2A;CNR1;GPR12;GPR55;HTR1A;PDE4D;PDE4A;OPRD1;CNR2;OPRM1 GO:0007568| aging CAT;PTGS2;HMGCR;PDE4D;NAPEPLD;HTR2A;SOD1;CNR1;CYP1A1 GO:0051591| response to cAMP PDE3A;AANAT GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;PDE3A;PPARG;CYP2C9 GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PDE4A;PDE4D;CHRNA7;PPARG;GPR18;PDE3A;SMPD1;PDE4C;PDE4B;PLA2G1B;CACNA1I GO:0043117| positive regulation of vascular permeability PDE3A;TRPV4 20124:[DB14011 DB08487] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08487|3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 20125:[DB14011 DB07306] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation PTGS2;PTGS1;NOS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;NOS2;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;NOS2 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0001666| response to hypoxia CYP1A1;NOS2;CAT;CHRNA7 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0010629| negative regulation of gene expression OPRD1;NOS2 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GSR;NOS2;GPX1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 20126:[DB14011 DB01427] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0071407| cellular response to organic cyclic compound TNF;CYP1A1;CYP1B1 GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4B GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;PDE3A;ABCC1;SMPD1;ABCG2 GO:0050830| defense response to Gram-positive bacterium TNF;PLA2G1B GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0042127| regulation of cell proliferation TNF;PTGS1;PTGS2 GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0043066| negative regulation of apoptotic process PDE3A;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TNF;PPARG GO:0009615| response to virus TNF;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;TNF;PPARG GO:0051591| response to cAMP PDE3A;AANAT GO:0000187| activation of MAPK activity TNF;PLA2G1B;SOD1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;TNF GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TNF;TRPA1 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PDE4B;PDE3A;GPR18;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TRPV1;OPRM1;PTGS2 GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF GO:0006955| immune response CNR2;OPRD1;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;ALOX15;IDO1;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNF;PLA2G1B GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0031622| positive regulation of fever generation CNR1;PTGS2;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;TNF;PPARG;SMPD1 GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PDE3A;PPARG;CYP2C9 GO:0006919| activation of caspase activity PPARG;TNF GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0043117| positive regulation of vascular permeability TRPV4;PDE3A GO:0050796| regulation of insulin secretion CNR1;TNF GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7;SMPD1;PDE3A;GPR18;PPARG;PLA2G1B;CACNA1I;PDE4B GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1;PTGS2 GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 20127:[DB14011 DB05229] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C8;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGIR;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP2C8;CYP1B1;CYP1A2 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP2C8;CYP3A5 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1;PTGIR GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP17A1;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PTGIR;GPR18;PPARG;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C9;CYP2C8;CYP2C19;CYP2D6 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP1B1;CYP2C9 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PTGIR GO:0070989| oxidative demethylation CYP2D6;CYP2C8;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0065009| regulation of molecular function PTGIR;TRPV1 GO:0097267| CYP2C19;CYP2C8;CYP1B1;CYP2C9;CYP1A1;CYP1A2 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;PTGIR;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A 20128:[DB14011 DB05488] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes CYP1A2 common pathways GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;ACAT1;AANAT GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;PTGS1;GPX1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0010468| regulation of gene expression CYP1A2 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;PTGS2;CNR2;CYP1A2;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 20129:[DB14011 DB03428] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03428|SU9516 CDK5;CDK1;CDK2 common genes common pathways GO:0031100| organ regeneration PPARG;CDK1 GO:0010468| regulation of gene expression CDK1;CYP1A2 GO:0009611| response to wounding GPX1;CDK5;CYP1A1 GO:0010033| response to organic substance PPARG;CYP1A1;CDK2;TRPA1;SOD1;CYP1A2;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent CDK5;PPARG GO:0048511| rhythmic process CDK5;PPARG;AANAT GO:0010628| positive regulation of gene expression TRPV4;CDK1 GO:0046688| response to copper ion CDK1;SOD1;AANAT GO:0006915| apoptotic process GPX1;CDK1;VDAC1;CDK5 GO:0030855| epithelial cell differentiation VDAC1;PPARG;CDK1 GO:0042220| response to cocaine CDK5;SMPD1;CNR1;OPRM1 GO:0000187| activation of MAPK activity PLA2G1B;SOD1;CDK1;CHRNA7 GO:0046686| response to cadmium ion CAT;CDK1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;CDK2 GO:0043066| negative regulation of apoptotic process SOD1;CDK1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2;CDK5 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;CDK2 GO:0070509| calcium ion import TRPV4;CACNA1I;CDK5;CACNA1G;CACNA1H GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;GLRB;TRPV1;GLRA1;CDK5 GO:0006367| transcription initiation from RNA polymerase II promoter CDK1;PPARG GO:0010243| response to organic nitrogen TRPV1;CDK1;PTGS2 GO:0007569| cell aging SOD1;CDK1 GO:0045893| positive regulation of transcription, DNA-dependent CDK2;PPARG GO:0042493| response to drug CAT;PTGS2;CYP1A2;CDK1;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1G;CDK5;CACNA1I;CACNA1H GO:0046718| entry of virus into host cell HTR2A;CDK1 GO:0014823| response to activity CDK1;CAT GO:0070301| cellular response to hydrogen peroxide CDK1;CYP1B1 GO:0045740| positive regulation of DNA replication CDK1;PLA2G1B GO:0051966| regulation of synaptic transmission, glutamatergic CDK5;CNR1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CDK1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0009636| response to toxin CDK1;CAT;GPX1;CYP1A1;CYP1B1 GO:0008283| cell proliferation CDK5;CYP1A1;HTR1A;CDK1;GPX1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CDK5 GO:0007399| nervous system development SMPD1;CDK5;GLRB GO:0048148| behavioral response to cocaine CDK5;HTR2A GO:0042542| response to hydrogen peroxide TRPA1;CDK1;SOD1;GPX1;CAT GO:0019233| sensory perception of pain OPRD1;PTGS2;CNR2;OPRM1;CNR1;HTR2A;TRPV1;TRPA1;CDK5 GO:0048678| response to axon injury SOD1;CDK1 GO:0045471| response to ethanol HMGCR;CDK1;OPRM1;CNR1;SOD1;CAT GO:0008542| visual learning HMGCR;CDK5 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;CDK5;GLRA1;CACNA1G;VDAC1;GLRB 20130:[DB14011 DB05032] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05032|REV131 HRH4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;HRH4;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0007194| negative regulation of adenylate cyclase activity HRH4;OPRM1 GO:0006954| inflammatory response HRH4;PTGS2;CNR2;PTGS1;ALOX5;ALOX15;IDO1;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;HRH4;OPRM1 GO:0007165| signal transduction GPR55;HTR1A;HRH4;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I 20131:[DB14011 DB03577] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways GO:0043312| neutrophil degranulation ACPP;ALOX5;CAT GO:0051930| regulation of sensory perception of pain ACPP;OPRM1;OPRD1 GO:0051289| protein homotetramerization CAT;ACPP;TRPA1;CRYZ;TRPV1;TRPM8 20132:[DB14011 DB06525] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06525|Ganstigmine ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development ACHE;CACNA1H GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0051262| protein tetramerization ACHE;HMGCR;CAT GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0008283| cell proliferation CYP1A1;GPX1;ACHE;HTR1A 20133:[DB14011 DB00173] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process HMGCR;ACACB GO:0010033| response to organic substance UGT1A1;PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0010628| positive regulation of gene expression TRPV4;SRPK2 GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;UGT1A1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9;UGT1A1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;PECR;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5 GO:0042493| response to drug ACACB;CAT;CYP1A2;PTGS2;HTR2A;SOD1;ABCG2;UGT1A1;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0006631| fatty acid metabolic process ACACB;PTGS1;PECR;PTGS2;ALOX15 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;CYP1A1;UGT1A1;IDO1 GO:0045087| innate immune response PPARG;SRPK2 GO:0043312| neutrophil degranulation ALOX5;CAT;APRT GO:0042594| response to starvation ACAT1;PPARG;UGT1A1 GO:0008284| positive regulation of cell proliferation SRPK2;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0035722| interleukin-12-mediated signaling pathway MTAP;SOD1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;MTAP GO:0014070| response to organic cyclic compound UGT1A1;PPARG;CYP1A1;TRPA1;ACACB;ACAT1;AANAT;PTGS2;CYP1A2 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;UGT1A1 GO:0032869| cellular response to insulin stimulus PLA2G1B;APRT;PPARG GO:0031999| negative regulation of fatty acid beta-oxidation ACACB;CNR1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0006633| fatty acid biosynthetic process ACACB;PTGS1;PTGS2;PECR;PLA2G1B GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0010629| negative regulation of gene expression OPRD1;ACACB GO:0031667| response to nutrient levels SOD1;ACACB GO:0007595| lactation APRT;SLC29A1 GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPM8;TRPV1;CAT;ACACB GO:0045471| response to ethanol UGT1A1;SOD1;CNR1;HMGCR;OPRM1;CAT GO:0001525| angiogenesis CYP1B1;SRPK2;PTGS2 GO:0001889| liver development ACAT1;CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1;CYP1A1;CYP2C19;CYP2D6 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;ACACB;HMGCR;CYP1A2;PTGS2;PECR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0035556| intracellular signal transduction SRPK2;PLA2G1B GO:0008152| metabolic process UGT1A1;SMPD1;ACAT1;ACACB 20134:[DB14011 DB00927] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes CYP2C19 common pathways GO:0007613| memory PTGS2;HRH2;CNR1;HTR2A;CHRNA7 GO:0045907| positive regulation of vasoconstriction HRH2;HTR2A;PTGS2 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HRH2;HTR2A;GPR12;CNR1;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0006811| ion transport CHRNA7;TRPV2;SLC22A8;GLRA3;CACNA1H;TRPV3;SLC22A2;TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPA1;GLRA1;CACNA1G GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;SLC22A8 GO:0006855| drug transmembrane transport SLC22A2;ABCG2;ABCC1 GO:0006812| cation transport TRPM8;SLC22A2 GO:0098656| SLC22A8;VDAC1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0006955| immune response HRH2;CNR2;OPRD1 GO:0048565| digestive tract development HRH2;CYP1A1 GO:0008542| visual learning HMGCR;HRH2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;HTR2A;GPR12;CNR1;HRH2;OPRM1;CNR2;OPRD1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0055085| transmembrane transport SLC22A8;CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;SLC22A2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;HRH2;CNR1 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 20135:[DB14011 DB09006] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes PPARG common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0019216| regulation of lipid metabolic process HMGCR;PPARA;CNR1;CYP1A1;PPARG GO:0007566| embryo implantation PPARD;PTGS2;SOD1 GO:1905461| PPARG GO:0014823| response to activity PPARD;CAT GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;SOD1;PPARD GO:0019395| fatty acid oxidation PPARG;PPARD GO:0060612| adipose tissue development ACAT1;PPARD GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARD;PPARG GO:0032868| response to insulin stimulus AANAT;CAT;PPARA;TRPV4 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0006919| activation of caspase activity PPARG GO:0008283| cell proliferation CYP1A1;HTR1A;PPARD;GPX1 GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;PPARD;HMGCR;PPARA;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1 GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG;PPARA;PPARD GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;PPARA;PPARD GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARD;PPARG GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:1904706| PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0046697| decidualization PPARD;PTGS2 GO:0015909| long-chain fatty acid transport PPARG GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PPARD;PTGS2 GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0031000| response to caffeine PPARG GO:0015758| glucose transport PLA2G1B;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PPARD;CYP1A2;PTGS2;SOD1 GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CAT;CHRNA7;PPARA;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;PPARD GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0006915| apoptotic process VDAC1;GPX1;PPARD GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042594| response to starvation PPARG;ACAT1 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PPARA;PPARD GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;PPARD;HMGCR;SOD1 GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PPARA GO:0008284| positive regulation of cell proliferation PTGS2;PPARD;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PPARD GO:0042060| wound healing ALOX15;PPARA;PPARD;OPRM1 GO:0033189| response to vitamin A PPARD;CAT;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARD;PPARA;PPARG GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0050728| negative regulation of inflammatory response CNR2;PPARD;PPARA GO:0071455| cellular response to hyperoxia PPARG GO:0030224| monocyte differentiation PPARG GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PPARA;PTGS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD;PPARA GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;PPARG GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2 20136:[DB14011 DB00979] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0050890| cognition CHRNA7;CHRM1 GO:0007165| signal transduction CNR1;GPR12;HTR2A;GPR55;HTR1A;CHRM1;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0008283| cell proliferation CYP1A1;GPX1;CHRM1;HTR1A GO:0008285| negative regulation of cell proliferation PPARG;BCHE;CYP1B1;OPRM1;PTGS2 GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0007399| nervous system development CHRM1;GLRB;SMPD1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;CHRM1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;CHRM1;HMGCR;PTGS2 GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;BCHE;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 20137:[DB14011 DB07577] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0007623| circadian rhythm TYMS;AANAT GO:0032259| methylation TYMS;CYP1A2 GO:0034097| response to cytokine stimulus TYMS;AANAT;PTGS2 GO:0042493| response to drug ABCG2;TRPA1;PPARG;TYMS;CYP1A1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0033189| response to vitamin A PPARG;CYP1A1;TYMS;CAT GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;TYMS;CYP1A1 GO:0045471| response to ethanol TYMS;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0014070| response to organic cyclic compound PPARG;TYMS;CYP1A1;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0009636| response to toxin CAT;GPX1;CYP1B1;TYMS;CYP1A1 GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR 20138:[DB14011 DB08604] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08604|Triclosan fabI;fabI;fabI;fabI;NR1I2;AR;NR1I3;PPARG;TPO common genes PPARG common pathways GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010628| positive regulation of gene expression AR;NR1I2;TRPV4 GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent NR1I3;NR1I2;PPARG GO:0042446| hormone biosynthetic process CYP17A1;TPO GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0042744| hydrogen peroxide catabolic process TPO;GPX1;CAT GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;TPO GO:0043388| positive regulation of DNA binding PPARG GO:0098869| TPO;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;NR1I2;CYP1A1;CYP2C9;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0010468| regulation of gene expression CYP1A2;AR GO:0015909| long-chain fatty acid transport PPARG GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;TRPV2;AR GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;AR;NR1I3 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0006355| regulation of transcription, DNA-dependent NR1I3;AR;NR1I2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG;AR GO:0030224| monocyte differentiation PPARG GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;GPX1;PTGS1;TPO;CRYZ;CYP1A1;CYP2C9;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR1I2;AR;NR1I3 GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;TRPV1;TRPV4;PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development PPARG;SOD1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;AR GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0008283| cell proliferation CYP1A1;GPX1;AR;HTR1A GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;ACAT1;AANAT GO:0007548| sex differentiation AR;CYP17A1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction AR;CHRNA7;CNR2;OPRM1;OPRD1;NR1I3;HTR1A;GPR55;HTR2A;GPR12;CNR1;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;NR1I2 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0042908| xenobiotic transport ABCG2;NR1I2;ABCC1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;NR1I2;CYP1A2;CYP3A4 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0006805| xenobiotic metabolic process NR1I2;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway AR;NR1I3;NR1I2;PPARG GO:0006351| transcription, DNA-dependent AR;NR1I3;NR1I2;PPARG 20139:[DB14011 DB07489] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07489|4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium CSNK1G3 common genes common pathways GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CSNK1G3;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I 20140:[DB14011 DB02811] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02811|Diethylphosphono Group BCHE;fbpC;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0007584| response to nutrient CNR1;HMGCR;PPARG;BCHE GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BCHE;PTGS2;OPRM1 GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;BCHE;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT 20141:[DB14011 DB00928] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00928|Azacitidine DNMT1;CDA common genes common pathways GO:0051289| protein homotetramerization TRPM8;TRPV1;CRYZ;TRPA1;CAT;CDA GO:0006351| transcription, DNA-dependent PPARG;DNMT1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CDA GO:0006355| regulation of transcription, DNA-dependent PPARG;DNMT1 GO:0030308| negative regulation of cell growth PPARG;CDA GO:0042127| regulation of cell proliferation DNMT1;PTGS1;PTGS2 GO:0071230| cellular response to amino acid stimulus GLRA1;DNMT1 GO:0032259| methylation DNMT1;CYP1A2 GO:0043312| neutrophil degranulation CDA;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;PPARG;TRPV1;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;DNMT1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;DNMT1 GO:0010468| regulation of gene expression CYP1A2;DNMT1 20142:[DB14011 DB04847] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04847|Roxadustat EGLN1;EGLN2;EGLN3 common genes common pathways GO:0006915| apoptotic process GPX1;EGLN3;VDAC1 GO:0001666| response to hypoxia EGLN3;EGLN1;EGLN2;CYP1A1;CAT;CHRNA7 GO:1901214| CHRNA7;EGLN1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;EGLN2;CYP2D6;EGLN1;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;EGLN3;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0043523| regulation of neuron apoptosis GPX1;EGLN3;EGLN2 GO:0042127| regulation of cell proliferation EGLN3;PTGS1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;EGLN1;PLA2G1B GO:0006919| activation of caspase activity PPARG;EGLN3 GO:0045454| cell redox homeostasis EGLN2;GSR;GPX1 GO:0006879| cellular iron ion homeostasis ABCG2;EGLN1;SOD1 20143:[DB14011 DB09369] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09369|Polyestradiol phosphate ESR1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;ESR1;GPR55;HTR1A;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ESR1;HTR2A;OPRM1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 20144:[DB14011 DB08734] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ACAT1;AANAT;TYMS;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;TYMS;CYP1A1 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;TYMS GO:0007568| aging NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT;CYP1A1;TYMS GO:0033189| response to vitamin A CAT;PPARG;CYP1A1;TYMS GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;TYMS;PPARG;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2;TYMS GO:0032259| methylation CYP1A2;TYMS GO:0007623| circadian rhythm TYMS;AANAT 20145:[DB14011 DB09116] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09116|Calcium carbimide ALDH3B2;CAT common genes CAT common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;PTGS1;ALOX5;GPX1;CYP1A1;ALDH3B2;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1 GO:0009642| response to light intensity CAT GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0034599| cellular response to oxidative stress GSR;SOD1;CAT;GPX1 GO:0008203| cholesterol metabolic process HMGCR;CAT GO:0000302| response to reactive oxygen species GPX1;CAT;SOD1 GO:0033197| response to vitamin E CAT GO:0020027| hemoglobin metabolic process CAT GO:0010288| response to lead ion CAT GO:0043312| neutrophil degranulation ALOX5;CAT GO:0001822| kidney development CAT GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT GO:0046686| response to cadmium ion CAT GO:0051262| protein tetramerization CAT;HMGCR GO:0001657| ureteric bud development CAT GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0010193| response to ozone CAT GO:0007568| aging CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0009060| aerobic respiration CAT GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0098869| GSR;PTGS2;CAT;GPX1;PTGS1 GO:0080184| response to phenylpropanoid CAT GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B GO:0051289| protein homotetramerization CAT;CRYZ;TRPA1;TRPV1;TRPM8 GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CAT GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;CYP2C9;ALDH3B2;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;CAT;SOD1 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0008152| metabolic process ALDH3B2;SMPD1;ACAT1 GO:0014854| response to inactivity CAT GO:0032868| response to insulin stimulus TRPV4;CAT;AANAT GO:0033591| response to L-ascorbic acid CAT GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0009411| response to UV CAT GO:0009636| response to toxin CYP1A1;CYP1B1;GPX1;CAT GO:0009650| UV protection GPX1;CAT GO:0014823| response to activity CAT GO:0051781| positive regulation of cell division CAT GO:0001649| osteoblast differentiation CAT GO:0006641| triglyceride metabolic process GPX1;CAT GO:0070542| response to fatty acid CAT;PTGS2 20146:[DB14011 DB09347] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09347|Acetrizoic acid ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0098869| GPX1;PTGS1;CAT;PTGS2;ALB;GSR GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process ALB;GPX1;CAT;HMGCR;PTGS2;SOD1 20147:[DB14011 DB09109] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09109|Turoctocog alfa F9;F10;F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;F2;PPARG;GPR18 GO:0009611| response to wounding GPX1;F2;CYP1A1 20148:[DB14011 DB05029] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05029|Lancovutide PLA2G4A common genes common pathways GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G4A GO:0036151| PLA2G1B;PLA2G4A GO:0042127| regulation of cell proliferation PLA2G4A;PTGS1;PTGS2 GO:0019369| arachidonic acid metabolic process PLA2G4A;CYP1B1;ALOX15;DAGLA;CYP2D6;FAAH GO:0036152| PLA2G1B;PLA2G4A GO:0006644| phospholipid metabolic process PLA2G4A;PLA2G1B;NAPEPLD GO:0016042| lipid catabolic process NAPEPLD;PLA2G4A;DAGLA;PLA2G1B GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG;PLA2G4A GO:0036148| PLA2G1B;PLA2G4A GO:0008152| metabolic process SMPD1;PLA2G4A;ACAT1 GO:0036149| PLA2G1B;PLA2G4A GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G4A GO:0036150| PLA2G1B;PLA2G4A GO:0009395| phospholipid catabolic process PLA2G4A;NAPEPLD 20149:[DB14011 DB00262] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00262|Carmustine GSR;CYP1A2 common genes CYP1A2;GSR common pathways GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0034599| cellular response to oxidative stress GSR;SOD1;CAT;GPX1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;CYP1A2;OPRM1;CNR1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;TRPA1 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0098869| GPX1;PTGS1;CAT;PTGS2;GSR GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0045333| cellular respiration CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0006749| glutathione metabolic process SOD1;GPX1;GSR GO:0045454| cell redox homeostasis GPX1;GSR GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 20150:[DB14011 DB08369] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2B6;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP2B6;CYP1A1;CYP2C9;CYP1A2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP2B6;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;CYP2B6;CYP2C9 20151:[DB14011 DB08348] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08348|N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE EEF2;PARP3;PARP15 common genes common pathways GO:0007568| aging CYP1A1;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT;EEF2 GO:0032355| response to estradiol stimulus CAT;EEF2;PTGS2;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PARP15;PPARG GO:0042493| response to drug CAT;EEF2;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1 GO:0043312| neutrophil degranulation EEF2;ALOX5;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PARP15;PPARG GO:0034976| response to endoplasmic reticulum stress ALOX15;EEF2 GO:0006351| transcription, DNA-dependent PPARG;PARP15 GO:0045471| response to ethanol CAT;EEF2;SOD1;CNR1;OPRM1;HMGCR GO:0042542| response to hydrogen peroxide CAT;GPX1;EEF2;SOD1;TRPA1 20152:[DB14011 DB07219] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07219|BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE CTSB common genes common pathways GO:0043312| neutrophil degranulation CTSB;CAT;ALOX5 GO:0046697| decidualization PTGS2;CTSB GO:0030855| epithelial cell differentiation CTSB;VDAC1;PPARG GO:0046718| entry of virus into host cell CTSB;HTR2A 20153:[DB14011 DB05876] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05876|PDE4 PDE4A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;PDE4A;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;PDE4A;GPR55;HTR1A;GPR12;CNR1;HTR2A;CHRNA7 20154:[DB14011 DB06441] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06441|Cangrelor P2RY12 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway P2RY12;OPRM1;OPRD1 GO:0065009| regulation of molecular function TRPV1;P2RY12 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;P2RY12;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B GO:0070588| calcium ion transmembrane transport CHRNA7;P2RY12;TRPV2;CACNA1H;OPRM1;TRPV3;TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;P2RY12 GO:0051924| regulation of calcium ion transport P2RY12;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway P2RY12;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0071318| cellular response to ATP PTGS2;SOD1;P2RY12;TRPV1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;P2RY12 20155:[DB14011 DB08645] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08645|6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE CA2 common genes common pathways GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CA2;TRPA1;CYP1A1;PPARG GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 20156:[DB14011 DB02431] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways GO:0008152| metabolic process SMPD1;UCK2;ACAT1 20157:[DB14011 DB09059] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0051412| response to corticosterone stimulus AVPR1A;AANAT GO:0007165| signal transduction AVPR1B;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;AVPR2;OPRM1;CNR2;OPRD1;HTR1A;GPR55;AVPR1A;HTR2A;CNR1;GPR12;OXTR;CHRNA7 GO:0032870| cellular response to hormone stimulus AVPR1A;OXTR;CACNA1H;AVPR2;AVPR1B GO:0045907| positive regulation of vasoconstriction AVPR1B;AVPR2;AVPR1A;OXTR;HTR2A;PTGS2 GO:0044849| OXTR;OPRM1 GO:0007613| memory CHRNA7;PTGS2;OXTR;HTR2A;CNR1 GO:0007204| elevation of cytosolic calcium ion concentration AVPR1A;OXTR;HTR2A;OPRM1;TRPV4;TRPV1;AVPR1B GO:0001975| response to amphetamine CNR2;OXTR;SOD1 GO:0043434| response to peptide hormone stimulus TRPV1;OXTR GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;AVPR1A GO:0045777| positive regulation of blood pressure CNR1;OXTR;AVPR1A;AVPR2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;OXTR;CYP1A2;PTGS2 GO:0042755| eating behavior OPRD1;OPRM1;OXTR GO:0007507| heart development PPARG;OXTR GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger AVPR2;CNR1 GO:0030431| sleep OXTR;HTR2A;SLC29A1;CACNA1I GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;OXTR GO:0048565| digestive tract development CYP1A1;OXTR GO:0007595| lactation SLC29A1;OXTR GO:0060137| maternal process involved in parturition OXTR;CYP1A1 GO:0007565| female pregnancy IDO1;OXTR GO:0006936| muscle contraction GLRA1;CACNA1H;OXTR GO:0032355| response to estradiol stimulus OXTR;CYP1A2;PTGS2;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;OXTR;GPR12;CNR1;HTR2A;AVPR1A;HTR1A;GPR55;AVPR1B;GPR18;PPARG;AVPR2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;OXTR GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;AVPR1A;CYP1A2;PTGS2 GO:0010628| positive regulation of gene expression AVPR2;TRPV4 GO:0007202| activation of phospholipase C activity HTR2A;AVPR1A;GPR55;AVPR1B GO:0042220| response to cocaine OXTR;CNR1;OPRM1;SMPD1 GO:0034097| response to cytokine stimulus PTGS2;OXTR;AANAT;AVPR2 GO:0008284| positive regulation of cell proliferation HTR1A;AVPR1A;HTR2A;PTGS2;HMGCR;CHRNA7;AVPR2 GO:0014902| myotube differentiation GPX1;AVPR1A GO:0051970| negative regulation of transmission of nerve impulse AVPR1A;GLRA1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;OXTR;HTR2A;SOD1 20158:[DB14011 DB07902] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07902|TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE METAP1 common genes common pathways 20159:[DB14011 DB08805] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08805|Metiamide HRH2 common genes common pathways GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HRH2;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0045907| positive regulation of vasoconstriction HRH2;HTR2A;PTGS2 GO:0007613| memory CHRNA7;PTGS2;HRH2;HTR2A;CNR1 GO:0048565| digestive tract development CYP1A1;HRH2 GO:0008542| visual learning HMGCR;HRH2 GO:0006955| immune response OPRD1;CNR2;HRH2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HRH2;CNR1;OPRD1;CNR2;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HRH2;GPR12;CNR1;HTR2A 20160:[DB14011 DB05459] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05459|Briakinumab IL12B;IL23A common genes common pathways GO:0006955| immune response OPRD1;CNR2;IL23A GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;ALOX5;PTGS1;IL23A GO:0032693| negative regulation of interleukin-10 production IL23A;IL12B;IDO1 GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPA1;TRPV1;IL12B GO:0007166| cell surface receptor linked signaling pathway IL12B;TRPV1;TRPA1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;IL12B GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IL12B GO:0050729| positive regulation of inflammatory response IL23A;IL12B;TRPV4 GO:0002862| negative regulation of inflammatory response to antigenic stimulus IL12B;GPX1 GO:0035722| interleukin-12-mediated signaling pathway IL12B;IL23A;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL23A;PLA2G1B;PPARG GO:0045087| innate immune response IL23A;PPARG GO:0010033| response to organic substance IL12B;PPARG;CYP1A1;TRPA1;SOD1;PTGS2;CYP1A2 GO:0002376| immune system process IDO1;IL23A GO:0032735| positive regulation of interleukin-12 production IL23A;IL12B;IDO1 20161:[DB14011 DB13003] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13003|Cortivazol NR3C1 common genes common pathways GO:0006915| apoptotic process NR3C1;GPX1;VDAC1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PPARG;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;NR3C1;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent NR3C1;PPARG 20162:[DB14011 DB08072] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08072|4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE PLAU common genes common pathways GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLAU;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0043312| neutrophil degranulation ALOX5;CAT;PLAU GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;PLAU 20163:[DB14011 DB00914] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes CYP2D6 common pathways GO:0045821| positive regulation of glycolysis PRKAA1;HTR2A GO:0006351| transcription, DNA-dependent PPARG;PRKAA1 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0007507| heart development KCNJ8;PPARG GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PRKAA1;PLA2G1B;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1 GO:0071361| cellular response to ethanol PRKAA1;GLRA1 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;TRPA1;PRKAA1 GO:0016126| sterol biosynthetic process PRKAA1;HMGCR GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0042752| regulation of circadian rhythm PPARG;PRKAA1 GO:0009268| response to pH TRPV1;KCNJ8 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PRKAA1;PLA2G1B;GPR18;PPARG;SMPD1 GO:0006633| fatty acid biosynthetic process PRKAA1;PLA2G1B;PTGS2;PTGS1 GO:0010332| response to gamma radiation PRKAA1;GPX1 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0034765| regulation of ion transmembrane transport KCNJ8;CACNA1H;CACNA1G;CACNA1I GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0048643| positive regulation of skeletal muscle tissue development PRKAA1;HMGCR GO:0006855| drug transmembrane transport ABCG2;SLC22A2;ABCC1;SLC22A1 GO:0006811| ion transport CACNA1H;TRPV3;KCNJ8;GLRA3;TRPV2;CHRNA7;CACNA1G;SLC22A1;TRPA1;GLRA1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;SLC22A2;TRPM8 GO:0009411| response to UV PRKAA1;CAT GO:0006812| cation transport SLC22A2;TRPM8;SLC22A1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;PRKAA1 GO:0014823| response to activity PRKAA1;CAT GO:0071380| cellular response to prostaglandin E stimulus PRKAA1;PPARG GO:0051291| protein heterooligomerization PRKAA1;GLRB;GLRA1 GO:0019395| fatty acid oxidation PRKAA1;PPARG GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0006695| cholesterol biosynthetic process HMGCR;PRKAA1 GO:0032496| response to lipopolysaccharide CNR1;KCNJ8;CYP1A2;OPRM1;CNR2;PTGS2;CYP1A1;IDO1 GO:0008203| cholesterol metabolic process HMGCR;CAT;PRKAA1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;PRKAA1 GO:0043066| negative regulation of apoptotic process PRKAA1;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0042311| vasodilation KCNJ8;GPX1 GO:0001822| kidney development CAT;KCNJ8 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0016236| macroautophagy VDAC1;PRKAA1 GO:0006355| regulation of transcription, DNA-dependent PPARG;PRKAA1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15;PRKAA1 GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;FAAH GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0006694| steroid biosynthetic process CYP17A1;PRKAA1;HMGCR GO:0071456| cellular response to hypoxia PRKAA1;OPRD1;PTGS2;SLC29A1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;PRKAA1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0051260| protein homooligomerization GLRA1;SLC22A1;GLRA3;ACAT1 GO:0042593| glucose homeostasis PPARG;PRKAA1;TRPV4;CNR1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;SLC22A1;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;SLC22A2 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;PRKAA1 GO:0048511| rhythmic process AANAT;PPARG;PRKAA1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0031000| response to caffeine PRKAA1;PPARG GO:0001666| response to hypoxia CAT;CHRNA7;PRKAA1;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;PRKAA1 20164:[DB14011 DB03221] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03221|AL7099A CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT 20165:[DB14011 DB07221] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways GO:0045540| regulation of cholesterol biosynthetic process GGPS1;HMGCR GO:0008299| isoprenoid biosynthetic process HMGCR;GGPS1 GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1 20166:[DB14011 DB01956] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes GLRA3;GLRA1 common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;GABBR1;OPRM1 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1 GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0060012| synaptic transmission, glycinergic GLRB;GLRA1;GLRA2;GLRA3 GO:0065009| regulation of molecular function TRPV1;GRIN2B GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GABRA5;GPR18;GABRP;PPARG;GABRD;CHRNA7;GABRB3;OPRD1;GABRB1;GABRQ;OPRM1;GABRE;GABBR1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;GABRA6 GO:0007420| brain development GABRA5;ACAT1 GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0006821| chloride transport GABRP;GLRA1;GABRD;GABRB2;GABRA5;GABRA3;GABRG1;GABRA2;GLRB;GABRA1;GLRA3;GABRA4;GABRA6;GABRB1;GABRG2;GABRQ;GABRE;GABRG3;GLRA2;GABRB3 GO:0009636| response to toxin GPX1;CAT;GABRB1;CYP1B1;CYP1A1 GO:0006811| ion transport GABRA1;GLRA3;GRIN2B;GABRA4;GABRA6;GABRQ;TRPV3;GABRG2;GABRB1;CACNA1H;GABRE;GABRG3;CHRNA7;GABRB3;GLRA2;TRPV2;SLC36A1;GLRA1;TRPA1;GABRP;SLC15A1;GABRD;GABRB2;GABRA3;GABRA5;CACNA1G;GABRG1;TRPM8;GABRA2;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1 GO:0001662| behavioral fear response GABRA5;VDAC1;HTR1A GO:0051291| protein heterooligomerization GLRB;GLRA1 GO:0009791| post-embryonic development GABRG2;CYP1A2 GO:0001889| liver development BAAT;ACAT1;CYP1A1 GO:0045471| response to ethanol CNR1;SOD1;GRIN2B;HMGCR;OPRM1;CAT GO:0071294| cellular response to zinc ion GLRA2;GLRA1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;GABBR1 GO:0071361| cellular response to ethanol GLRA1;GLRA2 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GABRA1 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;BAAT;CYP1A2;PTGS2;HMGCR;PTGS1;NAAA;GPX1 GO:0097305| GLRA1 GO:0007268| synaptic transmission GLRA1;GABRD;GABRB2;GABRA5;GABRG1;CACNA1G;GLRB;VDAC1;HTR2A;GLRA3;GRIN2B;OPRD1;GABRG2;OPRM1;GLRA2 GO:0043524| negative regulation of neuron apoptosis GABRB3;SOD1;GABRA5;GABRB2 GO:1902476| GABRG1;GABRA5;GABRA3;GABRB2;GABRD;GABRP;GLRA1;GLRB;GABRA2;GABRE;GABRG2;GABRB1;GABRQ;GABRA4;GABRA6;GABRA1;GLRA3;GLRA2;GABRB3;GABRG3 GO:0001964| startle response GLRA1;GLRB GO:0060013| righting reflex GLRB;GLRA1 GO:0006810| transport ABCG2;CACNA1I;TRPV1;SLC15A1;GABRD;GABRB2;ABCC1;GABRA3;GABRA5;GABRB3;TRPV2;GABRA1;GRIN2B;GABRA4;GABRA6;GABRB1;GABRG2;SLC6A6 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;GABBR1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0007605| sensory perception of sound GABRB2;GABRA5;GABRB3;GPX1;SOD1 GO:0006820| anion transport VDAC1;GLRA1 GO:0006936| muscle contraction CACNA1H;GLRA1 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;CACNA1H GO:0031100| organ regeneration BAAT;PPARG GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1 GO:0055085| transmembrane transport SLC36A1;TRPV2;CACNA1H;TRPV3;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;SLC15A1 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0043200| response to amino acid stimulus GLRB;GLRA3 GO:0034220| ion transmembrane transport GABRA2;GLRB;TRPV1;TRPA1;GLRA1;GABRP;GABRB2;GABRD;GABRA3;GABRA5;GABRG1;CHRNA7;GABRG3;GABRB3;GLRA2;GLRA3;GABRA1;GABRA6;GABRA4;GABRQ;GABRB1;GABRG2;GABRE GO:0060080| regulation of inhibitory postsynaptic membrane potential GABRB3;GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;GLRA1;CHRNA7;GLRA2;SLC29A1;GLRA3;GRIN2B;OPRM1 GO:0071230| cellular response to amino acid stimulus GLRA1;GLRA2 GO:0043523| regulation of neuron apoptosis GABRB3;GPX1;GABRB2;GABRA5 GO:0007611| learning or memory CHRNA7;CNR1;GRIN2B GO:0001508| regulation of action potential GLRA1;CACNA1G GO:0007628| adult walking behavior GLRB;GLRA1 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;GLRA3;OPRD1;OPRM1;GLRA2 GO:0007340| acrosome reaction GLRA1;GLRB GO:0050884| neuromuscular process controlling posture GLRA1 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;BAAT;PTGS2 GO:0050905| neuromuscular process GLRB;GLRA1 GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;GABRG3;CAT;HTR2A;SOD1;CYP1A2;PTGS2 20167:[DB14011 DB02889] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02889|4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose AMY2A;AMY2A common genes common pathways GO:0008152| metabolic process AMY2A;ACAT1;SMPD1 20168:[DB14011 DB01780] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01780|Fusicoccin YWHAE common genes common pathways GO:0034605| cellular response to heat YWHAE;PTGS2;TRPV1;TRPV4 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;YWHAE;PTGS2 GO:0016032| viral reproduction YWHAE;HTR2A;VDAC1 GO:0086091| CACNA1G;YWHAE GO:0035556| intracellular signal transduction YWHAE;PLA2G1B 20169:[DB14011 DB04465] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways GO:0061844| PLA2G1B;LGALS3 GO:0090280| positive regulation of calcium ion import TRPV3;LGALS3;TRPV2 GO:0045087| innate immune response PPARG;LGALS3 GO:0043312| neutrophil degranulation LGALS3;ALOX5;CAT GO:0030593| neutrophil chemotaxis PLA2G1B;LGALS3 GO:0006687| glycosphingolipid metabolic process GLTP;SMPD1 GO:0002376| immune system process LGALS3;IDO1 GO:0030855| epithelial cell differentiation LGALS3;PPARG;VDAC1 20170:[DB14011 DB01717] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways GO:0006139| nucleobase-containing compound metabolic process SLC29A1;AK2;AK1;AK8 GO:0015949| nucleobase-containing small molecule interconversion AK2;AK8;AK1;GSR 20171:[DB14011 DB07181] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0001666| response to hypoxia CHRNA7;CAT;DPP4;CYP1A1 20172:[DB14011 DB12887] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12887|Tazemetostat EZH2 common genes common pathways GO:0070301| cellular response to hydrogen peroxide EZH2;CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EZH2 GO:0006351| transcription, DNA-dependent PPARG;EZH2 GO:0010629| negative regulation of gene expression OPRD1;EZH2 GO:0042752| regulation of circadian rhythm PPARG;EZH2 GO:0032355| response to estradiol stimulus CAT;EZH2;CYP1A2;PTGS2 GO:0010468| regulation of gene expression CYP1A2;EZH2 GO:0045892| negative regulation of transcription, DNA-dependent EZH2;PPARG GO:0048511| rhythmic process EZH2;AANAT;PPARG GO:0043406| positive regulation of MAP kinase activity EZH2;HTR2A GO:0042127| regulation of cell proliferation PTGS2;EZH2;PTGS1 GO:0032259| methylation EZH2;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter EZH2;PPARG;TRPV4;TRPV1 GO:0006355| regulation of transcription, DNA-dependent EZH2;PPARG 20173:[DB14011 DB04763] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04763|1-N-(4-SULFAMOYLPHENYL-ETHYL)-2,4,6-TRIMETHYLPYRIDINIUM CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CA2;CYP1A1;PPARG;TRPA1 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG 20174:[DB14011 DB11831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11831|Dinitrochlorobenzene MGMT;GSTP1 common genes common pathways GO:0002674| negative regulation of acute inflammatory response PPARG;GSTP1 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;GSTP1 GO:0043200| response to amino acid stimulus GLRA3;GLRB;GSTP1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR;GSTP1 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;GPR18;CHRNA7 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;GSTP1 GO:0071407| cellular response to organic cyclic compound MGMT;CYP1A1;CYP1B1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;MGMT;SOD1;HTR2A GO:0032259| methylation CYP1A2;MGMT GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;MGMT;HMGCR;PTGS2;GSTP1 GO:0043312| neutrophil degranulation GSTP1;ALOX5;CAT GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1;GSTP1 GO:0034599| cellular response to oxidative stress SOD1;MGMT;GPX1;CAT;GSTP1;GSR GO:0006749| glutathione metabolic process GSTP1;GSR;SOD1;GPX1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0009636| response to toxin GPX1;CAT;MGMT;CYP1B1;GSTP1;CYP1A1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;ACAT1;AANAT;PTGS2;CYP1A2;MGMT GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0032869| cellular response to insulin stimulus PLA2G1B;GSTP1;PPARG GO:1904706| PPARG;GSTP1 GO:0031667| response to nutrient levels SOD1;GSTP1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;GSTP1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0008152| metabolic process ACAT1;SMPD1;GSTP1 GO:0045471| response to ethanol CAT;MGMT;SOD1;CNR1;OPRM1;HMGCR;GSTP1 20175:[DB14011 DB02628] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02628|1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;XIAP;SOD1 GO:0042127| regulation of cell proliferation XIAP;PTGS2;PTGS1 GO:0006915| apoptotic process GPX1;XIAP;VDAC1 GO:0050727| regulation of inflammatory response XIAP;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;XIAP;PTGS2 20176:[DB14011 DB05744] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;IL6;TNF GO:0050728| negative regulation of inflammatory response IL10;CNR2 GO:0034465| response to carbon monoxide SOD1;IL10 GO:0046427| positive regulation of JAK-STAT cascade IL6;CYP1B1 GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent IL10;PPARG;TNF;IL6 GO:0050830| defense response to Gram-positive bacterium TNF;CRP;PLA2G1B;IL6 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;IL10;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TNF;TRPV4;TRPV1 GO:0035722| interleukin-12-mediated signaling pathway IL10;SOD1 GO:0043066| negative regulation of apoptotic process IL10;IL6;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0009615| response to virus TNF;CYP1A1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;PLA2G1B;TNF;IL10;PPARG GO:0046330| positive regulation of JNK cascade TRPV4;TNF GO:0071230| cellular response to amino acid stimulus TNF;GLRA1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;TNF GO:0032496| response to lipopolysaccharide IDO1;IL10;CYP1A1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;TNF;CYP1A1;PPARG;IL10 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0042130| negative regulation of T cell proliferation IDO1;IL10 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0010628| positive regulation of gene expression TRPV4;IL6;TNF;CRP GO:0000187| activation of MAPK activity SOD1;CHRNA7;TNF;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;TNF;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0032966| negative regulation of collagen biosynthetic process IL6;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;TNF;OPRM1;PTGS2 GO:0032720| negative regulation of tumor necrosis factor production IL10;GPR18;CHRNA7 GO:0007568| aging CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;IL10;CYP1A1 GO:0097756| PTGS2;HMGCR;CRP GO:0030595| leukocyte chemotaxis IL10;CNR2 GO:0010468| regulation of gene expression IL10;CYP1A2 GO:0002446| neutrophil mediated immunity PLA2G1B;IL6 GO:1904706| PPARG;IL10 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL6 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL6;IL10;PPARG;TNF GO:0006955| immune response IL6;TNF;IL10;OPRD1;CNR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IL6;PLA2G1B;CAT GO:0006954| inflammatory response CRP;TNF;IL10;IL6;TRPV1;IDO1;ALOX15;PTGS2;CNR2;ALOX5;PTGS1 GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;IL6;TRPV1;CYP1B1;TNF;PPARG;SMPD1 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0031622| positive regulation of fever generation TNF;CNR1;PTGS2 GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;IL10;PPARG;CYP1B1;IL6 GO:0014823| response to activity IL10;CAT GO:0032930| positive regulation of superoxide anion generation CRP;SOD1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;IL6 GO:0014854| response to inactivity IL10;CAT GO:0032868| response to insulin stimulus CAT;AANAT;IL10;TRPV4 GO:0006919| activation of caspase activity TNF;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation CRP;PPARG GO:0051930| regulation of sensory perception of pain IL10;OPRM1;OPRD1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1;IL10 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;IL10;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;IL6;PTGS2;OPRD1 GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0050796| regulation of insulin secretion CNR1;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF;IL10;IL6 20177:[DB14011 DB08078] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways GO:0046697| decidualization PPARD;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0071456| cellular response to hypoxia OPRD1;PPARD;PTGS2;SLC29A1 GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0006915| apoptotic process VDAC1;PPARD;GPX1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PPARD;CYP1A2;PTGS2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0015758| glucose transport PLA2G1B;PPARD GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0042127| regulation of cell proliferation PTGS1;PPARD;PTGS2 GO:0042060| wound healing OPRM1;PPARD;ALOX15 GO:0008203| cholesterol metabolic process CAT;HMGCR;PPARD GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;PPARG;TRPV4;TRPV1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;PPARD;HMGCR GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;PPARD;HMGCR;CHRNA7 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARG GO:0033189| response to vitamin A CAT;PPARD;CYP1A1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0050728| negative regulation of inflammatory response CNR2;PPARD GO:0007566| embryo implantation SOD1;PTGS2;PPARD GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0008283| cell proliferation HTR1A;PPARD;GPX1;CYP1A1 GO:0014823| response to activity PPARD;CAT GO:0019395| fatty acid oxidation PPARD;PPARG GO:0060612| adipose tissue development ACAT1;PPARD GO:0001890| placenta development PPARG;SOD1;PPARD GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARG GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0006351| transcription, DNA-dependent PPARD;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;PPARD;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1 GO:0007507| heart development PPARD;PPARG 20178:[DB14011 DB02866] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02866|Dansylamide CA2 common genes common pathways GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG;CA2 GO:0001822| kidney development CA2;CAT 20179:[DB14011 DB05867] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 20180:[DB14011 DB12228] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;CALCRL GO:0045986| negative regulation of smooth muscle contraction PTGS2;CALCRL GO:0050728| negative regulation of inflammatory response CALCRL;CNR2 GO:0050830| defense response to Gram-positive bacterium CALCA;PLA2G1B GO:0019731| antibacterial humoral response PLA2G1B;CALCA GO:0008284| positive regulation of cell proliferation CALCRL;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045087| innate immune response PPARG;CALCA GO:0043542| endothelial cell migration CALCA;CYP1B1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger CALCA;GPR18;GPR55 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1;CALCRL GO:0045671| negative regulation of osteoclast differentiation GPR55;CALCA GO:0006874| cellular calcium ion homeostasis TRPV4;CALCB;TRPM8;CHRNA7;GPR12;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PPARG;CALCRL;CALCA;GPR18;CALCB GO:0006816| calcium ion transport CACNA1H;TRPV3;TRPV2;CHRNA7;CACNA1G;CALCRL;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8 GO:0007507| heart development CALCRL;PPARG GO:0045776| negative regulation of blood pressure CNR1;CALCA GO:0007166| cell surface receptor linked signaling pathway CALCRL;TRPA1;TRPV1 GO:0001525| angiogenesis PTGS2;CYP1B1;CALCRL GO:0008217| regulation of blood pressure PPARG;CALCA;PTGS1;SOD1;PTGS2 GO:0061844| PLA2G1B;CALCA GO:0007165| signal transduction CALCB;CACNA1I;PLA2G1B;GPR18;CALCRL;PPARG;SMPD1;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 20181:[DB14011 DB00489] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes CYP2D6 common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0042391| regulation of membrane potential CACNA1H;KCNH2;CACNA1G;GLRA1;GLRB GO:0007186| G-protein coupled receptor signaling pathway ADRB1;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;ADRB2;HTR2A;CNR1;GPR12 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1;TRPV3;KCNH2;CACNA1H;TRPV2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;ADRB2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0002024| diet induced thermogenesis TRPV1;ADRB1;TRPV4;ADRB2 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;DAGLA;CYP2D6 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1 GO:0007165| signal transduction CACNA1I;ADRB1;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;ADRB2;HTR1A;GPR55 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0045453| bone resorption GPR55;ADRB2 GO:0034765| regulation of ion transmembrane transport KCNH2;CACNA1H;CACNA1G;CACNA1I GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006811| ion transport TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;KCNH2;TRPV3;GLRA3 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRB2;CNR1 GO:0001659| temperature homeostasis TRPV1;ADRB1;GPX1;HTR2A GO:0009409| response to cold TRPM8;ADRB1;TRPA1;PPARG;ADRB2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2;ADRB2;ADRB1 GO:0007166| cell surface receptor linked signaling pathway ADRB2;TRPA1;TRPV1 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0086091| KCNH2;CACNA1G GO:0086010| KCNH2;CACNA1H;CACNA1G;CACNA1I 20182:[DB14011 DB05003] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05003|Imexon RRM2;RRM1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;RRM1;ALOX15;RRM2;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0008152| metabolic process SMPD1;RRM1;ACAT1 GO:0015949| nucleobase-containing small molecule interconversion RRM1;GSR;RRM2 20183:[DB14011 DB03667] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes PTGS1 common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP1A1;CYP2C9;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B 20184:[DB14011 DB02261] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;GM2A;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;PTAFR GO:0045776| negative regulation of blood pressure CNR1;PTAFR GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;PTAFR;ALOX15;IDO1;TRPV1 GO:0006955| immune response CNR2;OPRD1;PTAFR GO:0071320| cellular response to cAMP AANAT;PTAFR GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;PTAFR GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;PTAFR;GPR18;SMPD1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0009609| response to symbiotic bacterium GPX1;PTAFR GO:0045987| positive regulation of smooth muscle contraction PTAFR;PTGS2 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0043312| neutrophil degranulation PTAFR;GM2A;CAT;ALOX5 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;PTAFR;CYP1A1;IDO1 GO:0007611| learning or memory CHRNA7;CNR1;GM2A GO:0048661| positive regulation of smooth muscle cell proliferation PTAFR;HMGCR;PTGS2 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCB1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PTAFR;PPARG GO:0006687| glycosphingolipid metabolic process GM2A;SMPD1 GO:0006810| transport TRPV2;ABCG2;CACNA1I;ABCB1;TRPV1;ABCC1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1 20185:[DB14011 DB02562] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02562|Quinonoid 7,8-Tetrahydrobiopterin PAH common genes common pathways GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;PAH GO:0042136| neurotransmitter biosynthetic process PAH;DAGLA GO:0008152| metabolic process PAH;SMPD1;ACAT1 20186:[DB14011 DB00730] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes CYP1A1;CYP1A2 common pathways GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0017143| insecticide metabolic process CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;CYP1A1;PPARG GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009624| response to nematode CYP1A1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0043010| camera-type eye development CYP1A1 GO:0097267| CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:1900087| CYP1A1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:0032502| developmental process CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0009635| response to herbicide CYP1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0009692| ethylene metabolic process CYP1A1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0001889| liver development CYP1A1;ACAT1 GO:0070988| demethylation CYP1A1 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0071615| oxidative deethylation CYP1A2 GO:0010041| response to iron(III) ion CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0009611| response to wounding CYP1A1;GPX1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0010468| regulation of gene expression CYP1A2 GO:0007568| aging HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0009308| amine metabolic process CYP1A1 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0046685| response to arsenic-containing substance CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0032094| response to food OPRM1;CYP1A1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0009615| response to virus CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0009812| flavonoid metabolic process CYP1A1 20187:[DB14011 DB01963] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 20188:[DB14011 DB03359] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0008283| cell proliferation HTR1A;ACHE;GPX1;CYP1A1 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development SMPD1;GLRB;ACHE 20189:[DB14011 DB04978] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04978|SP1049C TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;PLA2G1B GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0043065| positive regulation of apoptotic process TOP2A;PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 20190:[DB14011 DB04419] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04419|D-norleucine PTH;HNF1A;PAH common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;PAH;CRYZ;CYP1A1;CYP2C9;GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0006355| regulation of transcription, DNA-dependent HNF1A;PPARG GO:0042493| response to drug CAT;PTH;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent HNF1A;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PTH GO:0010288| response to lead ion CAT;PTH GO:0045944| positive regulation of transcription from RNA polymerase II promoter PTH;HNF1A;PPARG;PLA2G1B GO:0046686| response to cadmium ion PTH;CAT GO:0007202| activation of phospholipase C activity PTH;GPR55;HTR2A GO:0010468| regulation of gene expression CYP1A2;PTH GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;PTH;OPRD1;PPARG;GPR18 GO:0042593| glucose homeostasis TRPV4;HNF1A;PPARG;CNR1 GO:0006874| cellular calcium ion homeostasis CHRNA7;PTH;GPR12;HTR2A;TRPV4;TRPM8 GO:0031667| response to nutrient levels PTH;SOD1 GO:0045471| response to ethanol OPRM1;PTH;HMGCR;CNR1;SOD1;CAT GO:0006351| transcription, DNA-dependent HNF1A;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter HNF1A;PPARG GO:0008152| metabolic process PAH;SMPD1;ACAT1 GO:0042136| neurotransmitter biosynthetic process DAGLA;PAH GO:0033280| response to vitamin D PTH;PTGS2 GO:0045453| bone resorption PTH;GPR55 20191:[DB14011 DB05205] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05205|CX157 MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;MAOA;HMGCR 20192:[DB14011 DB04090] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04090|RH-1 NQO1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;NQO1 GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0055114| oxidation-reduction process NQO1;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;NQO1 GO:0007568| aging CYP1A1;NQO1;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CAT GO:0032355| response to estradiol stimulus NQO1;CYP1A2;PTGS2;CAT GO:0006805| xenobiotic metabolic process NQO1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0045471| response to ethanol CNR1;SOD1;OPRM1;HMGCR;CAT;NQO1 GO:0019430| removal of superoxide radicals NQO1;SOD1 GO:0070301| cellular response to hydrogen peroxide NQO1;CYP1B1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;NQO1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NQO1 GO:0009636| response to toxin CYP1A1;NQO1;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;NQO1;ACAT1;AANAT;PTGS2;CYP1A2 20193:[DB14011 DB08293] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08293|(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0001890| placenta development HSP90AB1;PPARG;SOD1 GO:0006805| xenobiotic metabolic process CYP2C9;HSP90AB1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0043524| negative regulation of neuron apoptosis HSP90AB1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AB1;TRPV1 GO:0042220| response to cocaine CNR1;OPRM1;SMPD1;HSP90AB1 GO:0010033| response to organic substance HSP90AB1;TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AB1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;HSP90AB1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;HSP90AB1 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;HSP90AB1;SMPD1 20194:[DB14011 DB02132] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02132|Zenarestat AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0043066| negative regulation of apoptotic process AKR1B1;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0055114| oxidation-reduction process CRYZ;AKR1B1;CYP2C9;CYP1A1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;AKR1B1 20195:[DB14011 DB00761] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0001525| angiogenesis SLC12A6;PTGS2;CYP1B1 GO:0007268| synaptic transmission SLC12A6;OPRM1;OPRD1;GLRA3;HTR2A;VDAC1;GLRB;SLC12A5;CACNA1G;SLC12A7;SLC12A4;GLRA1 GO:0071476| cellular hypotonic response TRPV4;SLC12A6 GO:1902476| SLC12A5;GLRB;SLC12A4;GLRA1;SLC12A7;SLC12A1;SLC12A6;GLRA3;SLC12A2 GO:0006821| chloride transport SLC12A2;GLRA3;GLRA1;GLRB;SLC12A5 GO:0006971| hypotonic response TRPV4;SLC12A5 GO:0006811| ion transport GLRA3;CACNA1H;SLC12A2;TRPV3;SLC12A1;CHRNA7;SLC12A6;TRPV2;SLC12A4;GLRA1;TRPA1;SLC12A7;CACNA1G;SLC12A5;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1 GO:0007612| learning SLC12A5;VDAC1;PTGS2 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;SLC12A5;ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0071477| cellular hypotonic salinity response SLC12A6;TRPV4 GO:0006810| transport SLC12A1;TRPV2;SLC12A2;ABCG2;CACNA1I;TRPV1;SLC12A4;SLC12A7;ABCC1 GO:0007568| aging CYP1A1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;SLC12A2;PTGS2 GO:0006884| cell volume homeostasis SLC12A7;SLC12A4;TRPV4 GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;TRPV1;GLRA3;CHRNA7;SLC12A1 GO:0055085| transmembrane transport SLC12A2;CACNA1H;TRPV3;SLC12A1;TRPV2;SLC12A6;SLC12A4;TRPA1;CACNA1G;SLC12A7;ABCC1;ABCG2;SLC12A5;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4 20196:[DB14011 DB04426] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04426|Alpha-Methyl-N-Acetyl-D-Glucosamine MBL2 common genes common pathways GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1;MBL2 GO:0002376| immune system process IDO1;MBL2 GO:0045087| innate immune response PPARG;MBL2 GO:0050830| defense response to Gram-positive bacterium MBL2;PLA2G1B 20197:[DB14011 DB07251] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07251|N'-(3-CHLORO-4-METHOXY-PHENYL)-N-(3,4,5-TRIMETHOXYPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0001525| angiogenesis PTGS2;CYP1B1;EPHB4 GO:0007155| cell adhesion EPHB4;CYP1B1 20198:[DB14011 DB04983] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04983|Denufosol P2RY2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;P2RY2;GPR18;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger P2RY2;OPRD1;OPRM1;HTR2A GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;P2RY2 20199:[DB14011 DB06137] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06137|KX-01 SRC common genes common pathways GO:0002376| immune system process SRC;IDO1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0009615| response to virus CYP1A1;SRC GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;SRC;GPX1 GO:0042127| regulation of cell proliferation SRC;PTGS1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;SRC;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2 GO:0016236| macroautophagy SRC;VDAC1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;SRC;CHRNA7 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0045453| bone resorption SRC;GPR55 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;SRC GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SRC;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042542| response to hydrogen peroxide SOD1;CAT;SRC;GPX1;TRPA1 GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;SRC GO:0031667| response to nutrient levels SRC;SOD1 20200:[DB14011 DB04271] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;PDE4D;OPRM1;CNR2;GPR18;PPARG GO:0007568| aging CYP1A1;PTGS2;HMGCR;PDE4D;NAPEPLD;SOD1;HTR2A;CNR1;CAT GO:0030593| neutrophil chemotaxis PLA2G1B;PDE4D GO:0006939| smooth muscle contraction HTR2A;PDE4D GO:0007165| signal transduction GPR12;CNR1;HTR2A;HTR1A;GPR55;PDE4D;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0002027| regulation of heart rate CACNA1G;PDE4D 20201:[DB14011 DB11714] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11714|Durvalumab CD274;CD80 common genes common pathways GO:0034097| response to cytokine stimulus AANAT;PTGS2;CD274 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;CD80 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD80 GO:0042130| negative regulation of T cell proliferation IDO1;CD274 GO:0035556| intracellular signal transduction PLA2G1B;CD80 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CD274;TRPV1 GO:0006955| immune response CD274;CNR2;OPRD1 GO:0016032| viral reproduction VDAC1;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0032693| negative regulation of interleukin-10 production IDO1;CD274 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;CD274;GPR18;SMPD1 GO:0046006| regulation of activated T cell proliferation IDO1;CD274 GO:0046718| entry of virus into host cell CD80;HTR2A 20202:[DB14011 DB03753] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes PTGS1 common pathways GO:0098869| GSR;GPX1;PTGS1;CAT;PTGS2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;PTGS1;NAAA;GPX1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;IDO1;ALOX15 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 20203:[DB14011 DB14634] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14634|Fluprednidene acetate CYP3A4 common genes CYP3A4 common pathways GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 20204:[DB14011 DB08455] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08455|Ro 12-7310 CRABP2 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;CRABP2 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7;CRABP2 20205:[DB14011 DB03499] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03499|Malate Ion fumC;glcB;ME2;CS common genes common pathways GO:0008152| metabolic process ME2;ACAT1;SMPD1 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ME2;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0022900| electron transport chain CYP1A2;ME2;GSR;IDO1 20206:[DB14011 DB02486] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways GO:0006749| glutathione metabolic process GSTA1;GSR;GPX1;SOD1 GO:0008152| metabolic process ACAT1;GSTA1;SMPD1 GO:0030855| epithelial cell differentiation PPARG;VDAC1;GSTA1 GO:0098869| GSTA1;GSR;PTGS2;GPX1;PTGS1;CAT 20207:[DB14011 DB06543] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06543|Astaxanthin NFKBIA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NFKBIA GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;NFKBIA GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;NFKBIA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NFKBIA;PLA2G1B GO:0032496| response to lipopolysaccharide NFKBIA;IDO1;CYP1A1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NFKBIA GO:0071356| cellular response to tumor necrosis factor NFKBIA;TRPV1 GO:0006915| apoptotic process VDAC1;NFKBIA;GPX1 GO:0010468| regulation of gene expression CYP1A2;NFKBIA GO:0016032| viral reproduction HTR2A;NFKBIA;VDAC1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;NFKBIA;PLA2G1B GO:0000060| protein import into nucleus, translocation OPRD1;NFKBIA GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;NFKBIA GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;NFKBIA;CYP1B1 GO:0071345| cellular response to cytokine stimulus TRPV1;NFKBIA GO:0050729| positive regulation of inflammatory response TRPV4;NFKBIA 20208:[DB14011 DB06994] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;DPP4;VDAC1 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001666| response to hypoxia CHRNA7;CAT;DPP4;CYP1A1 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043542| endothelial cell migration CYP1B1;DPP4 20209:[DB14011 DB07604] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07604|(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE ATP2A1 common genes common pathways GO:0070509| calcium ion import ATP2A1;TRPV4;CACNA1I;CACNA1G;CACNA1H GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;ATP2A1;GLRA3;CHRNA7 GO:0006816| calcium ion transport CACNA1I;TRPV4;TRPV1;TRPM8;ATP2A1;CACNA1G;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3 GO:0034976| response to endoplasmic reticulum stress ATP2A1;ALOX15 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;ATP2A1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;GLRA1;TRPA1;CACNA1G GO:0070588| calcium ion transmembrane transport TRPV4;CACNA1I;TRPV1;ATP2A1;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1 20210:[DB14011 DB00154] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes PTGS1;PTGS2 common pathways GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP2C9;CYP1A1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;FABP7 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0022008| neurogenesis DAGLA;FABP7 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;IDO1;ALOX15;TRPV1 GO:0001964| startle response FABP7;GLRA1;GLRB GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0007399| nervous system development SMPD1;GLRB;FABP7 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:1990776| PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1;TRPA1;TRPV1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 20211:[DB14011 DB03487] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03487|3-Aminosuccinimide LYZ common genes common pathways GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B GO:0043312| neutrophil degranulation LYZ;ALOX5;CAT GO:0006954| inflammatory response TRPV1;LYZ;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0008152| metabolic process LYZ;SMPD1;ACAT1 GO:0001895| retina homeostasis LYZ;SOD1 20212:[DB14011 DB08908] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RELA GO:0006355| regulation of transcription, DNA-dependent PPARG;KEAP1;RELA GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;CAT;RELA;CYP1A2;PTGS2;HTR2A;SOD1 GO:0043278| response to morphine OPRM1;RELA;CNR1 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;CYP1A2;RELA;OPRM1;CNR1;IDO1;CYP1A1 GO:0034097| response to cytokine stimulus AANAT;PTGS2;RELA GO:0000122| negative regulation of transcription from RNA polymerase II promoter RELA;PPARG;TRPV4;TRPV1 GO:0043066| negative regulation of apoptotic process SOD1;RELA;PTGS2;HMGCR;CAT;GPX1 GO:0009612| response to mechanical stimulus RELA;PPARG;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;RELA GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;RELA;PTGS2;HTR2A;HTR1A GO:0051591| response to cAMP RELA;AANAT GO:0043200| response to amino acid stimulus GLRB;GLRA3;RELA GO:0045892| negative regulation of transcription, DNA-dependent PPARG;RELA GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2;RELA GO:0071356| cellular response to tumor necrosis factor TRPV1;RELA GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;RELA;HMGCR;CYP1A1 GO:0061614| RELA;PPARG GO:0016032| viral reproduction HTR2A;RELA;VDAC1 GO:0006954| inflammatory response PTGS2;CNR2;RELA;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;RELA;CAT GO:0001889| liver development CYP1A1;RELA;ACAT1 GO:0006351| transcription, DNA-dependent PPARG;KEAP1;RELA GO:0042542| response to hydrogen peroxide GPX1;CAT;RELA;SOD1;TRPA1 GO:0050727| regulation of inflammatory response PTGS2;RELA GO:0032868| response to insulin stimulus AANAT;CAT;RELA;TRPV4 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;RELA;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0070301| cellular response to hydrogen peroxide RELA;CYP1B1 20213:[DB14011 DB05104] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05104|Asimadoline OPRK1 common genes common pathways GO:0009314| response to radiation OPRM1;PTGS2;CAT;OPRK1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0045471| response to ethanol OPRK1;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0019233| sensory perception of pain HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1;TRPA1;OPRK1;TRPV1 GO:0006955| immune response OPRK1;CNR2;OPRD1 GO:0007600| sensory perception OPRK1;TRPV2;OPRM1 GO:0007268| synaptic transmission OPRK1;VDAC1;GLRB;GLRA1;CACNA1G;GLRA3;HTR2A;OPRM1;OPRD1 GO:0044849| OPRK1;OPRM1 GO:0007610| behavior OPRK1;HTR1A;HTR2A GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRK1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRD1;OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1 GO:0042755| eating behavior OPRM1;OPRD1;OPRK1 GO:0032868| response to insulin stimulus AANAT;CAT;OPRK1;TRPV4 GO:0007218| neuropeptide signaling pathway OPRK1;GLRB;GLRA1;GLRA3;OPRM1;OPRD1 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRK1;OPRD1;OPRM1;HTR2A GO:0043278| response to morphine OPRK1;OPRM1;CNR1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRK1;PPARG;GPR18 GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0042220| response to cocaine SMPD1;OPRK1;OPRM1;CNR1 20214:[DB14011 DB04297] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04297|7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide HDAC8;HDAC7 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter HDAC8;HDAC7;TRPV1;TRPV4;PPARG GO:0006355| regulation of transcription, DNA-dependent HDAC7;HDAC8;PPARG GO:0045892| negative regulation of transcription, DNA-dependent HDAC7;PPARG GO:0007043| cell-cell junction assembly TRPV4;HDAC7 GO:0006351| transcription, DNA-dependent PPARG;HDAC7;HDAC8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;HDAC7 GO:0010629| negative regulation of gene expression OPRD1;HDAC8 20215:[DB14011 DB06841] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06841|D-phenylalanyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl)butyl]-L-prolinamide F2 common genes common pathways GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;F2;GPR18;PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;F2 GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 20216:[DB14011 DB02090] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02090|A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor MMP3 common genes common pathways 20217:[DB14011 DB05013] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways GO:0070301| cellular response to hydrogen peroxide PRKCD;CYP1B1 GO:0032930| positive regulation of superoxide anion generation PRKCD;SOD1 GO:0050796| regulation of insulin secretion CNR1;PRKCA GO:0007165| signal transduction SMPD1;PRKCD;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;PRKCD;GPX1 GO:0001525| angiogenesis PRKCA;CYP1B1;PTGS2 GO:0035556| intracellular signal transduction PRKCA;PLA2G1B;PRKCD GO:0042307| positive regulation of protein import into nucleus PTGS2;PRKCD GO:0045766| positive regulation of angiogenesis CYP1B1;PRKCA;CHRNA7 GO:0006915| apoptotic process GPX1;PRKCA;VDAC1;PRKCD GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;PRKCA;ALOX15;TRPV4 GO:0043407| negative regulation of MAP kinase activity PRKCD;SMPD1;HMGCR GO:0023021| termination of signal transduction PRKCD;SMPD1 GO:0060326| cell chemotaxis PRKCD;ABCC1 GO:0050728| negative regulation of inflammatory response CNR2;PRKCD GO:0035307| positive regulation of protein dephosphorylation SMPD1;PRKCD GO:0043312| neutrophil degranulation PRKCD;ALOX5;CAT GO:0007155| cell adhesion PRKCA;CYP1B1 20218:[DB14011 DB04803] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04803|Verdoheme HMOX1 common genes common pathways GO:0045766| positive regulation of angiogenesis CHRNA7;HMOX1;CYP1B1 GO:0008219| cell death HTR2A;HMOX1 GO:0006915| apoptotic process VDAC1;GPX1;HMOX1 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;HMOX1 GO:0071456| cellular response to hypoxia SLC29A1;HMOX1;PTGS2;OPRD1 GO:0034605| cellular response to heat TRPV1;TRPV4;HMOX1;PTGS2 GO:0006979| response to oxidative stress PTGS2;HMOX1;SOD1;GPX1;PTGS1;CAT GO:0051260| protein homooligomerization GLRA1;GLRA3;HMOX1;ACAT1 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP3A4;HMOX1;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0035094| response to nicotine CNR1;HMOX1;CHRNA7 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2;HMGCR GO:0008217| regulation of blood pressure PTGS1;SOD1;HMOX1;PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;HMOX1;PPARG;CYP1B1 GO:1902042| GPX1;HMOX1 GO:0043627| response to estrogen stimulus PPARG;HMOX1 GO:0071276| cellular response to cadmium ion HMOX1;SOD1;CYP1A2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;HMOX1 GO:0043524| negative regulation of neuron apoptosis SOD1;HMOX1 GO:1904706| PPARG;HMOX1 GO:0006879| cellular iron ion homeostasis HMOX1;SOD1;ABCG2 GO:0001525| angiogenesis PTGS2;HMOX1;CYP1B1 GO:0035556| intracellular signal transduction PLA2G1B;HMOX1 GO:0042542| response to hydrogen peroxide TRPA1;CAT;GPX1;SOD1;HMOX1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;HMOX1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 20219:[DB14011 DB05706] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;TOP2A;SMPD1;CNR1;SOD1;PTGS2 GO:0042752| regulation of circadian rhythm PPARG;TOP2A 20220:[DB14011 DB04487] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04487|N-Methylleucine CXCL10 common genes common pathways GO:0009409| response to cold PPARG;TRPA1;CXCL10;TRPM8 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CXCL10;TRPV1 GO:0006955| immune response CXCL10;CNR2;OPRD1 GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;IDO1;ALOX15;TRPV1;CXCL10 GO:0045859| regulation of protein kinase activity SOD1;CXCL10 GO:0010332| response to gamma radiation CXCL10;GPX1 GO:0007165| signal transduction PLA2G1B;CACNA1I;CXCL10;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0043950| positive regulation of cAMP-mediated signaling CXCL10;OPRM1 GO:0061844| PLA2G1B;CXCL10 GO:0033280| response to vitamin D CXCL10;PTGS2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;CXCL10 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;CXCL10 GO:0009615| response to virus CYP1A1;CXCL10 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CXCL10 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CXCL10;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0016525| negative regulation of angiogenesis PPARG;CXCL10 GO:0007517| muscle organ development CXCL10;CACNA1H GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1;CXCL10 GO:0007186| G-protein coupled receptor signaling pathway CXCL10;GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 20221:[DB14011 DB08167] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08167|Methylthioninium ACHE common genes common pathways GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0008283| cell proliferation ACHE;HTR1A;GPX1;CYP1A1 20222:[DB14011 DB11584] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11584|Pipradrol DRD1;DRD5 common genes common pathways GO:0042053| regulation of dopamine metabolic process DRD1;HTR1A GO:0001662| behavioral fear response DRD1;HTR1A;VDAC1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;DRD5;DRD1;CHRNA7 GO:0001975| response to amphetamine CNR2;SOD1;DRD5;DRD1 GO:0072593| reactive oxygen species metabolic process SOD1;DRD5 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7;DRD1 GO:0019226| transmission of nerve impulse SOD1;DRD5;DRD1 GO:0008542| visual learning HMGCR;DRD1 GO:0007268| synaptic transmission DRD5;OPRD1;OPRM1;GLRA3;HTR2A;VDAC1;GLRB;CACNA1G;GLRA1 GO:0048148| behavioral response to cocaine HTR2A;DRD1 GO:0001659| temperature homeostasis TRPV1;HTR2A;DRD1;GPX1 GO:0019228| regulation of action potential in neuron DRD1;CACNA1H;CACNA1I;CACNA1G GO:0045776| negative regulation of blood pressure CNR1;DRD5 GO:0010628| positive regulation of gene expression TRPV4;DRD1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;GPR55;DRD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1;DRD1 GO:0042220| response to cocaine SMPD1;DRD5;DRD1;OPRM1;CNR1 GO:0006936| muscle contraction CACNA1H;DRD1;GLRA1 GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;HTR2A;GPR12;DRD5;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;DRD1;DRD5;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;DRD1;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1;DRD5;DRD1 GO:0042311| vasodilation DRD1;GPX1 GO:0007626| locomotory behavior DRD1;SOD1;OPRM1 GO:0007628| adult walking behavior GLRB;GLRA1;DRD1 GO:0007612| learning VDAC1;DRD1;DRD5;PTGS2 GO:0042060| wound healing ALOX15;OPRM1;DRD5 20223:[DB14011 DB08658] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08658|ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation CYP1B1;BCHE;PPARG;PTGS2;OPRM1 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0042493| response to drug ABCG2;ABCC1;SMPD1;BCHE;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0007612| learning VDAC1;BCHE;PTGS2 20224:[DB14011 DB02221] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02221|4-(Aminosulfonyl)-N-[(2,4,6-Trifluorophenyl)Methyl]-Benzamide CA2 common genes common pathways GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance CA2;PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 20225:[DB14011 DB05492] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05492|Epicept NP-1 OPRM1;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;OPRL1 common genes HTR2A;OPRM1 common pathways GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0046718| entry of virus into host cell HTR2A GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRL1;ADRA2A GO:0007204| elevation of cytosolic calcium ion concentration OPRL1;ADRA1B;OPRM1;HTR2A;ADRA1A;TRPV4;TRPV1;ADRA1D GO:0050796| regulation of insulin secretion ADRA2C;CNR1;ADRA2A GO:0007613| memory HTR2A;CNR1;PTGS2;HRH1;CHRNA7 GO:0071315| cellular response to morphine OPRM1 GO:0045907| positive regulation of vasoconstriction ADRA1B;ADRA2C;HTR2A;PTGS2;HRH1;ADRA1A;ADRA1D GO:0001819| positive regulation of cytokine production SOD1;ADRA2A;HTR2B GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I GO:0006939| smooth muscle contraction HTR2B;ADRA1A;HTR2A GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;HTR2B GO:0044849| OPRM1;OPRL1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0009725| response to hormone stimulus ADRA1A;ACAT1 GO:0007165| signal transduction CACNA1I;ADRA1A;PLA2G1B;ADRA2A;HTR2C;HTR2B;ADRA1D;SMPD1;PPARG;GPR18;OPRL1;ADRA1B;CHRNA7;CNR2;OPRM1;HRH1;OPRD1;ADRA2C;HTR1A;GPR55;CNR1;GPR12;HTR2A;ADRA2B GO:0007610| behavior HTR2B;HTR2C;HTR1A;HTR2A;OPRL1 GO:0043267| negative regulation of potassium ion transport HTR2A GO:0008283| cell proliferation ADRA1D;CYP1A1;HTR1A;GPX1;ADRA1B GO:0042755| eating behavior OPRL1;OPRD1;OPRM1 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADRA2C;OPRL1 GO:0045777| positive regulation of blood pressure CNR1;ADRA2B GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1D;ADRA1A GO:0045600| positive regulation of fat cell differentiation HTR2C;PPARG;HTR2A GO:0051781| positive regulation of cell division CAT;HTR2B GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;ADRA1A;PPARG GO:0046883| regulation of hormone secretion HTR1A;HTR2A GO:0001662| behavioral fear response HTR1A;VDAC1;HTR2C GO:0030818| negative regulation of cAMP biosynthetic process OPRL1;OPRM1;ADRA2A GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1;OPRL1;TRPA1;TRPV1 GO:0030431| sleep HTR2A;SLC29A1;CACNA1I GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT GO:0045821| positive regulation of glycolysis HTR2A GO:0045776| negative regulation of blood pressure OPRL1;CNR1 GO:0048148| behavioral response to cocaine HTR2A GO:0035556| intracellular signal transduction ADRA1A;PLA2G1B;ADRA1B GO:0042310| vasoconstriction HTR1A;HTR2B GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADRA1D;ADRA1B;CNR1 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A;HTR2C GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0001659| temperature homeostasis TRPV1;HTR2A;GPX1 GO:0007507| heart development HTR2B;PPARG GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission VDAC1;GLRB;HTR2C;CACNA1G;GLRA1;OPRL1;OPRM1;OPRD1;HTR2A;GLRA3 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain TRPA1;HTR2A GO:0007565| female pregnancy IDO1;ADRA2B;ADRA2C GO:0060454| positive regulation of gastric acid secretion OPRL1;TRPV1 GO:0016032| viral reproduction HTR2A;VDAC1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;HRH1;PTGS1;ALOX5 GO:0007600| sensory perception OPRM1;OPRL1;TRPV2 GO:0008542| visual learning HRH1;HMGCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1;OPRL1 GO:0033674| positive regulation of kinase activity HTR2A GO:0007186| G-protein coupled receptor signaling pathway ADRA1A;HTR2B;HTR2C;ADRA2A;ADRA1D;PPARG;GPR18;OPRL1;ADRA1B;OPRM1;CNR2;OPRD1;HRH1;GPR55;HTR1A;ADRA2C;ADRA2B;HTR2A;GPR12;CNR1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;HTR2C;HTR2B;TRPV1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;OPRL1 GO:0038003| opioid receptor signaling pathway OPRM1;OPRD1;OPRL1 GO:0007568| aging CYP1A1;ADRA1A;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:0007210| serotonin receptor signaling pathway HTR2B;HTR2C;HTR1A;HTR2A GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0006874| cellular calcium ion homeostasis HTR2B;HTR2C;TRPM8;TRPV4;CHRNA7;HTR2A;GPR12 GO:0042593| glucose homeostasis ADRA1B;CNR1;ADRA2A;TRPV4;PPARG GO:0071502| cellular response to temperature stimulus HTR2B;TRPV1 GO:0008219| cell death HTR2A GO:0042220| response to cocaine SMPD1;CNR1;OPRM1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;ADRA2B;PLA2G1B GO:0006915| apoptotic process VDAC1;ADRA1A;GPX1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;HTR2C;HTR2B;ALOX15;TRPV4;ADRA1A GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007202| activation of phospholipase C activity ADRA1A;HTR2B;GPR55;HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;HTR2C;GPR55 GO:0014059| regulation of dopamine secretion HTR2A GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A;HTR2B GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;CNR2;OPRM1;OPRD1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0042060| wound healing OPRM1;ALOX15 GO:0014824| artery smooth muscle contraction HTR2A GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus ADRA2A;HMGCR GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;TRPV1;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2B;HTR2C;ADRA1A;ADRA1D;ADRA1B;HTR2A;OPRD1;HRH1;OPRM1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;HTR2B GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0008284| positive regulation of cell proliferation ADRA2A;HTR2B;ADRA1D;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0007626| locomotory behavior SOD1;OPRM1;HTR2C GO:0007218| neuropeptide signaling pathway GLRB;GLRA1;OPRL1;OPRD1;OPRM1;GLRA3 GO:0070848| response to growth factor stimulus OPRM1 GO:0050795| regulation of behavior HTR1A;HTR2A;HTR2B GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0032094| response to food OPRM1;CYP1A1 GO:0042493| response to drug ABCG2;HTR2B;HTR2C;ADRA1A;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0044380| protein localization to cytoskeleton HTR2A GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2C;HTR2B;HTR2A GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A GO:0043278| response to morphine OPRM1;CNR1 GO:0032100| positive regulation of appetite OPRM1 20226:[DB14011 DB02498] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02498|Carba-Nicotinamide-Adenine-Dinucleotide PARP1 common genes common pathways GO:0006915| apoptotic process PARP1;GPX1;VDAC1 GO:0034599| cellular response to oxidative stress GSR;SOD1;PARP1;CAT;GPX1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;PLA2G1B;PPARG GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PARP1 GO:0010332| response to gamma radiation GPX1;PARP1 GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0071294| cellular response to zinc ion GLRA1;PARP1 20227:[DB14011 DB02123] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0046718| entry of virus into host cell HTR2A;SLC10A1 GO:0006811| ion transport TRPM8;SLC10A1;SLC10A2;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;SLCO1A2;CACNA1H GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;ABCB11 GO:0016032| viral reproduction SLC10A1;VDAC1;HTR2A GO:0006810| transport TRPV2;ABCB11;ABCG2;CACNA1I;TRPV1;SLC10A1;SLC10A2;ABCC1 GO:0055085| transmembrane transport SLC10A1;SLC10A2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;SLCO1A2;TRPV3;CACNA1H;ABCB11 20228:[DB14011 DB05890] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05890|VEGF-AS VEGFA common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;VEGFA GO:0001822| kidney development VEGFA;CAT GO:0043066| negative regulation of apoptotic process VEGFA;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0002576| platelet degranulation SOD1;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;VEGFA GO:0030324| lung development VEGFA;CYP1A2 GO:0030224| monocyte differentiation PPARG;VEGFA GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;VEGFA;SLC29A1 GO:0043406| positive regulation of MAP kinase activity HTR2A;VEGFA GO:0010628| positive regulation of gene expression VEGFA;TRPV4 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;VEGFA GO:0030855| epithelial cell differentiation VEGFA;PPARG;VDAC1 GO:0045766| positive regulation of angiogenesis VEGFA;CHRNA7;CYP1B1 GO:0001541| ovarian follicle development SOD1;VEGFA GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;VEGFA;OPRM1;HMGCR;GPR55;HTR2A GO:0007399| nervous system development VEGFA;GLRB;SMPD1 GO:0048469| cell maturation PPARG;VEGFA GO:0001525| angiogenesis CYP1B1;VEGFA;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;VEGFA GO:0007595| lactation VEGFA;SLC29A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0001934| positive regulation of protein phosphorylation VEGFA;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;VEGFA;PTGS2 GO:0043117| positive regulation of vascular permeability VEGFA;TRPV4 GO:0051781| positive regulation of cell division CAT;VEGFA 20229:[DB14011 DB07779] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DPP4 20230:[DB14011 DB12328] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12328|Cantharidin AHR common genes common pathways GO:0048511| rhythmic process AHR;PPARG;AANAT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;AHR GO:0006915| apoptotic process VDAC1;AHR;GPX1 GO:0010468| regulation of gene expression AHR;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARG;AHR GO:0045893| positive regulation of transcription, DNA-dependent AHR;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;AHR;PLA2G1B GO:0009410| response to xenobiotic stimulus AHR;GPX1 GO:0009636| response to toxin GPX1;CAT;AHR;CYP1A1;CYP1B1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;AHR GO:0006351| transcription, DNA-dependent AHR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG 20231:[DB14011 DB08043] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0007155| cell adhesion CYP1B1;ABL1 GO:0045087| innate immune response PPARG;ABL1 GO:0042127| regulation of cell proliferation ABL1;PTGS1;PTGS2 GO:0043542| endothelial cell migration ABL1;CYP1B1 GO:0034599| cellular response to oxidative stress GSR;ABL1;SOD1;GPX1;CAT GO:0006915| apoptotic process GPX1;VDAC1;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;ALOX15;ABL1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;ABL1 GO:0048538| thymus development ABL1;SOD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;ABL1;IDO1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4;ABL1 20232:[DB14011 DB00034] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00034|Interferon Alfa-2a, Recombinant IFNAR1;IFNAR2 common genes common pathways GO:0009615| response to virus IFNAR1;IFNAR2;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;OPRM1;IFNAR1;CYP1A2;PTGS2;CNR2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;IFNAR2 20233:[DB14011 DB00817] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes CYP1A2 common pathways GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;PTGS1;NAAA;GPX1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0045333| cellular respiration CYP1A2 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP1B1 GO:0032259| methylation CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;CYP1A1;IDO1 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 20234:[DB14011 DB07623] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP2A6;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP2A6;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP2A6;CYP1A2 GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP2A6;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0009804| coumarin metabolic process CYP2A6;CYP1A1;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2A6;CYP2C9;CYP1A1;CYP1B1;CYP2C19 20235:[DB14011 DB07524] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07524|N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine PIM1 common genes common pathways GO:0008283| cell proliferation GPX1;HTR1A;PIM1;CYP1A1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;PIM1;SOD1;GPX1;CAT GO:0006915| apoptotic process VDAC1;PIM1;GPX1 20236:[DB14011 DB07248] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PTK2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PTK2 GO:0043542| endothelial cell migration PTK2;CYP1B1 GO:0043066| negative regulation of apoptotic process PTK2;SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;PTK2 GO:0045087| innate immune response PPARG;PTK2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PTK2 GO:0001890| placenta development PTK2;PPARG;SOD1 GO:0001525| angiogenesis PTK2;CYP1B1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;PTK2 GO:0043087| regulation of GTPase activity SOD1;PTK2 20237:[DB14011 DB02778] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02778|2,5-Anhydroglucitol-1,6-Biphosphate FBP1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;PPARG;TRPV1;TRPV4 GO:0030308| negative regulation of cell growth FBP1;PPARG GO:0051289| protein homotetramerization TRPV1;TRPM8;CRYZ;TRPA1;FBP1;CAT GO:0008152| metabolic process FBP1;ACAT1;SMPD1 20238:[DB14011 DB00900] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes SLC29A1 common pathways GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;CYP1A1;PNP;PPARG;TRPA1;ABCC1;SMPD1 GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0002576| platelet degranulation SOD1;ALB GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;CHRNA7;SLC29A1;GLRA3;OPRM1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;SLC22A6;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0098869| PTGS1;GPX1;CAT;PTGS2;ALB;GSR GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:1901642| SLC29A1;SLC29A2 GO:0007595| lactation SLC29A1 GO:0015858| nucleoside transport SLC29A2;SLC29A1 GO:0006955| immune response OPRD1;CNR2;PNP GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0015862| uridine transport SLC29A1 GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0098656| VDAC1;SLC22A6 GO:0001895| retina homeostasis ALB;SOD1 GO:0008283| cell proliferation GPX1;SLC29A2;HTR1A;CYP1A1 GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A2;SLC29A1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 20239:[DB14011 DB03951] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 20240:[DB14011 DB05319] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05319|Oportuzumab monatox EPCAM common genes common pathways GO:0001657| ureteric bud development CAT;EPCAM GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;EPCAM GO:0008284| positive regulation of cell proliferation EPCAM;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 20241:[DB14011 DB02812] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02812|(2s,4r)-1-Acetyl-N-[(1s)-4-[(Aminoiminomethyl)Amino]-1-(2-Benzothiazolylcarbonyl)Butyl]-4-Hydroxy-2-Pyrrolidinecarboxamide PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20242:[DB14011 DB07254] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07254|N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL]AMINO]PHENYL]METHANESULFONAMIDE EPHB4 common genes common pathways GO:0001525| angiogenesis EPHB4;CYP1B1;PTGS2 GO:0007155| cell adhesion EPHB4;CYP1B1 20243:[DB14011 DB08804] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV1;TRPV4 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;AR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MAOB;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0006694| steroid biosynthetic process CYP17A1;CYP19A1;HMGCR GO:0055114| oxidation-reduction process CRYZ;CYP19A1;CYP1A1;CYP2C9;MAOB;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;MAOA;CAT;ALOX5;GPX1;PTGS1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;MAOB;TRPA1;CYP1A1;PPARG;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0022900| electron transport chain CYP1A2;CYP19A1;MAOB;GSR;IDO1 GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport AR;TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis SOD1;CNR1;AR GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1;MAOB GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP19A1 GO:0045471| response to ethanol MAOB;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;AR GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;AR;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;AR GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation HTR1A;AR;GPX1;CYP1A1 GO:0010269| response to selenium ion MAOB;GPX1 GO:0009636| response to toxin CYP1B1;CYP1A1;MAOB;CAT;GPX1 20244:[DB14011 DB08516] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08516|(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0009636| response to toxin CYP1B1;MAOB;CYP1A1;GPX1;CAT GO:0010269| response to selenium ion MAOB;GPX1 GO:0032496| response to lipopolysaccharide IDO1;MAOB;CYP1A1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0022900| electron transport chain CYP1A2;MAOB;GSR;IDO1 GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;TRPA1;MAOB;SMPD1;ABCC1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;MAOB;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;GPX1;ALOX5;PTGS1 GO:0050665| hydrogen peroxide biosynthetic process MAOB;CYP1A1;CYP1A2;SOD1 20245:[DB14011 DB01342] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01342|Forasartan AGTR1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0050729| positive regulation of inflammatory response AGTR1;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;AGTR1;TRPV4;TRPV1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7;AGTR1;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0042127| regulation of cell proliferation PTGS1;AGTR1;PTGS2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;AGTR1 GO:0001822| kidney development AGTR1;CAT GO:0060326| cell chemotaxis AGTR1;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;AGTR1;GPR18;PPARG GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;GPR55;AGTR1 20246:[DB14011 DB05049] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05049|DDP733 HTR3A common genes common pathways GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;VDAC1;GLRB;HTR3A;GLRA1;CACNA1G GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;HTR3A GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;HTR3A;TRPM8 GO:0007165| signal transduction GPR18;PPARG;SMPD1;HTR3A;PLA2G1B;CACNA1I;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0034220| ion transmembrane transport HTR3A;GLRB;TRPV1;GLRA1;TRPA1;CHRNA7;GLRA3 GO:0042220| response to cocaine HTR3A;SMPD1;OPRM1;CNR1 GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1;HTR3A 20247:[DB14011 DB03553] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03553|Glutaric Acid ilvE;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0051260| protein homooligomerization SLC22A6;GLRA1;ACAT1;GLRA3 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;SLC22A6;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1;SLC22A8;TRPV3;CACNA1H;SLC22A11;SLC22A7;TRPV2 GO:0098656| SLC22A8;SLC22A7;SLC22A6;VDAC1 GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;SLC22A11;CHRNA7;SLC22A7;TRPV3;CACNA1H;SLC22A8;GLRA3 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0046415| urate metabolic process SLC22A11;ABCG2 20248:[DB14011 DB07900] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07900|3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE MMP8 common genes common pathways GO:0043312| neutrophil degranulation MMP8;CAT;ALOX5 20249:[DB14011 DB00605] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes PTGS1;CYP1A1;PTGS2 common pathways GO:0000187| activation of MAPK activity PLA2G1B;SOD1;MAPK3;CHRNA7 GO:0006915| apoptotic process VDAC1;MAPK3;PPARD;GPX1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;SLC22A6;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;MAPK3;OPRM1;HMGCR GO:0034612| response to tumor necrosis factor PTGS2 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0002933| CYP3A7;CYP3A4;CYP3A5;CYP1A1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARD;CYP1A1;PPARG;AKR1B1;TRPA1 GO:0045892| negative regulation of transcription, DNA-dependent PPARD;PPARG GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0015758| glucose transport PPARD;PLA2G1B GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1;PTGDR2 GO:0071356| cellular response to tumor necrosis factor MAPK3;TRPV1 GO:0010628| positive regulation of gene expression MAPK3;PPARD;TRPV4 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0007568| aging SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0046697| decidualization PTGS2;PPARD GO:0030282| bone mineralization PTGS2;ALOX15 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;PPARD;OPRD1 GO:0008202| steroid metabolic process AKR1B10;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0009611| response to wounding GPX1;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PTGDR2;PPARG;GPR18 GO:1902219| PTGS2 GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| ALB;GSR;GPX1;PTGS1;CAT;PTGS2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0010041| response to iron(III) ion CYP1A1 GO:0051260| protein homooligomerization SLC22A6;GLRA1;GLRA3;ACAT1 GO:0048538| thymus development SOD1;MAPK3 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;AKR1B10;CRYZ;AKR1B1;CYP2C9;CYP1A1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0032094| response to food OPRM1;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0022900| electron transport chain GSR;IDO1;AKR1B1;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;PPARD;CAT GO:0009750| response to fructose stimulus PTGS2 GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD GO:0019372| lipoxygenase pathway GPX1;ALOX5;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0009308| amine metabolic process CYP1A1 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;MAPK3;FAAH GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;PPARD GO:0071284| cellular response to lead ion PTGS2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0030308| negative regulation of cell growth PPARG;PPARD GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PPARD GO:0042060| wound healing OPRM1;PPARD;ALOX15 GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0007612| learning VDAC1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR2;PTGS2;MAPK3;CYP1A2;OPRM1;CNR1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PPARD GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB;PTGS2;PPARD;HMGCR;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0002576| platelet degranulation ALB;SOD1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PPARD;PTGS2;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MAPK3 GO:0007218| neuropeptide signaling pathway GLRA3;OPRD1;OPRM1;PTGDR2;GLRA1;GLRB GO:0009615| response to virus CYP1A1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001895| retina homeostasis ALB;SOD1 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0009624| response to nematode CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin MAPK3;GPX1;CAT;CYP1A1;CYP1B1 GO:0033280| response to vitamin D PTGS2 GO:0008283| cell proliferation PPARD;HTR1A;GPX1;CYP1A1 GO:0098656| VDAC1;SLC22A6 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0070365| hepatocyte differentiation CYP1A1 GO:0014823| response to activity PPARD;CAT GO:0019395| fatty acid oxidation PPARD;PPARG GO:0060612| adipose tissue development ACAT1;PPARD GO:0001890| placenta development SOD1;PPARD;PPARG GO:0001523| retinoid metabolic process AKR1B10;NAPEPLD GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071276| cellular response to cadmium ion CYP1A2;MAPK3;SOD1 GO:0045600| positive regulation of fat cell differentiation PPARD;HTR2A;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0017143| insecticide metabolic process CYP1A1 GO:0032502| developmental process CYP1A1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;PTGDR2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PPARD;PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:1900087| CYP1A1 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;CHRNA7;PTGDR2;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0043010| camera-type eye development CYP1A1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0001934| positive regulation of protein phosphorylation MAPK3;CHRNA7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0009635| response to herbicide CYP1A1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0007268| synaptic transmission GLRB;VDAC1;GLRA1;CACNA1G;PTGDR2;GLRA3;HTR2A;OPRD1;OPRM1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0048565| digestive tract development CYP1A1 GO:0016032| viral reproduction MAPK3;HTR2A;VDAC1 GO:0006955| immune response PTGDR2;CNR2;OPRD1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;PTGS2;CNR2 GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARD GO:0010759| positive regulation of macrophage chemotaxis MAPK3;TRPV4 GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0006351| transcription, DNA-dependent MAPK3;PPARD;PPARG GO:0019233| sensory perception of pain OPRD1;MAPK3;OPRM1;CNR2;PTGS2;HTR2A;CNR1;TRPV1;TRPA1 GO:0001889| liver development ACAT1;CYP1A1 GO:0070988| demethylation CYP1A1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0009692| ethylene metabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;PTGS2;CYP1A2;PPARD;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2;MAPK3 GO:0007507| heart development PPARD;PPARG GO:0035556| intracellular signal transduction MAPK3;PLA2G1B GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0030728| ovulation PTGS2 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0042307| positive regulation of protein import into nucleus PTGS2 20250:[DB14011 DB03796] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;CYP2C8;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA;SEC14L2 GO:0006631| fatty acid metabolic process PPARA;PTGS2;PTGS1;ALOX15;FABP3 GO:0006355| regulation of transcription, DNA-dependent PPARA;SEC14L2;HNF4G;PPARG GO:0050830| defense response to Gram-positive bacterium PLA2G1B;LALBA GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;FABP3;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARG;HNF4G GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0030308| negative regulation of cell growth PPARG;PPT1 GO:0042060| wound healing ALOX15;PPARA;OPRM1 GO:0043312| neutrophil degranulation CAT;ALOX5;FABP5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PPARA GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;PPT1;ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C8;CYP1A1;CYP2C9 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HNF4G;PPARG;PLA2G1B;PPARA GO:0002576| platelet degranulation ALB;SOD1 GO:0006915| apoptotic process LALBA;GPX1;PAEP;VDAC1 GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0045540| regulation of cholesterol biosynthetic process HMGCR;SEC14L2 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5;CYP2C8 GO:0016042| lipid catabolic process DAGLA;PLA2G1B;NAPEPLD;PPT1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;FABP4 GO:0071356| cellular response to tumor necrosis factor TRPV1;FABP4 GO:0009416| response to light stimulus AANAT;RHO GO:0048511| rhythmic process PPARG;AANAT;PPARA GO:0001666| response to hypoxia CHRNA7;CAT;PPARA;CYP1A1 GO:0015909| long-chain fatty acid transport PPARG;FABP3 GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;RHO;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP1A2;CYP3A4 GO:0098869| PTGS2;GPX1;PTGS1;CAT;ALB;GSR GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0043524| negative regulation of neuron apoptosis PPT1;SOD1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C8;CYP2C9;CYP1A2;CYP3A4 GO:0007268| synaptic transmission GLRA1;CACNA1G;VDAC1;GLRB;GLRA3;HTR2A;PPT1;OPRD1;OPRM1 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;PAEP GO:0050872| white fat cell differentiation FABP4;PPARG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0006351| transcription, DNA-dependent SEC14L2;PPARA;PPARG;HNF4G GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG;HNF4G GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0006357| regulation of transcription from RNA polymerase II promoter HNF4G;PPARG GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;PPARA;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;FABP5;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG GO:0007399| nervous system development GLRB;SMPD1;PPT1 GO:0007507| heart development PPARG;PPARA GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0001895| retina homeostasis SOD1;ALB GO:0032868| response to insulin stimulus PPARA;CAT;AANAT;TRPV4;FABP3 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0008285| negative regulation of cell proliferation FABP3;CYP1B1;PPARG;PTGS2;OPRM1 GO:0001523| retinoid metabolic process RHO;NAPEPLD GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0050896| response to stimulus PPT1;RHO;TRPA1;TRPM8 GO:0007601| visual perception CYP1B1;GLRB;RHO;CRYZ;GLRA1;PPT1 GO:0019216| regulation of lipid metabolic process HMGCR;PPARA;CNR1;PPARG;CYP1A1 GO:0050729| positive regulation of inflammatory response FABP4;TRPV4 GO:0070542| response to fatty acid FABP3;CAT;PTGS2 GO:0065009| regulation of molecular function TRPV1;TRAPPC3 GO:0097267| CYP1B1;CYP2C8;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0007420| brain development PPT1;ACAT1 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;LALBA;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7;SMPD1;RHO;GPR18;PPARG;CACNA1I;PLA2G1B GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2C8;CYP2D6 20251:[DB14011 DB07847] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07847|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 20252:[DB14011 DB05187] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes PPARG common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0050872| white fat cell differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;PPARD;NAPEPLD;CYP3A4;PPARA;NAAA;GPX1;PTGS1 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARG;PPARD;PPARA GO:0045165| cell fate commitment PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0045598| regulation of fat cell differentiation PPARG;PPARD GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARA;PPARG GO:0006351| transcription, DNA-dependent PPARG;PPARD;PPARA GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0048469| cell maturation PPARG GO:0055088| lipid homeostasis PPARG GO:0060612| adipose tissue development ACAT1;PPARD GO:0019395| fatty acid oxidation PPARD;PPARG GO:0001890| placenta development PPARD;SOD1;PPARG GO:0045600| positive regulation of fat cell differentiation PPARD;HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0014823| response to activity CAT;PPARD GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0008283| cell proliferation CYP1A1;PPARD;HTR1A;GPX1 GO:0032868| response to insulin stimulus PPARA;AANAT;CAT;TRPV4 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0007566| embryo implantation PPARD;PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARA;CYP1A1;PPARG GO:1905461| PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2;PPARD GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A PPARD;CAT;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0006367| transcription initiation from RNA polymerase II promoter PPARA;PPARD;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARA;PPARD;PPARG GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PPARA;PTGS1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARD;PPARG GO:0030224| monocyte differentiation PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PPARD;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;PPARD;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;PLA2G1B GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;PPARA;TRPV4;TRPV1;PPARG GO:0045087| innate immune response PPARG GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0008203| cholesterol metabolic process HMGCR;PPARD;CAT GO:0042060| wound healing PPARA;OPRM1;PPARD;ALOX15 GO:0042127| regulation of cell proliferation PTGS2;PPARD;PTGS1 GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0032526| response to retinoic acid PPARG GO:0001666| response to hypoxia CAT;CHRNA7;PPARA;CYP1A1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0010033| response to organic substance CYP1A2;PTGS2;PPARD;SOD1;CYP1A1;PPARG;TRPA1 GO:0015758| glucose transport PLA2G1B;PPARD GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0006915| apoptotic process VDAC1;GPX1;PPARD GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0015909| long-chain fatty acid transport PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PPARD;CAT GO:0046697| decidualization PTGS2;PPARD GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1;PPARD GO:0010468| regulation of gene expression CYP1A2;PPARA 20253:[DB14011 DB05838] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05838|OPC-51803 AVPR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PPARG;GPR18;AVPR2 GO:0010628| positive regulation of gene expression TRPV4;AVPR2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;AVPR2 GO:0034097| response to cytokine stimulus AANAT;PTGS2;AVPR2 GO:0045907| positive regulation of vasoconstriction AVPR2;HTR2A;PTGS2 GO:0032870| cellular response to hormone stimulus AVPR2;CACNA1H GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;AVPR2;CACNA1I;PLA2G1B GO:0045777| positive regulation of blood pressure AVPR2;CNR1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;AVPR2 20254:[DB14011 DB03107] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;ABCC1;CACNA1G;TRPV2;SLC16A10;TRPV3;CACNA1H 20255:[DB14011 DB07026] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07026|(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE MMP12 common genes common pathways GO:0042060| wound healing ALOX15;OPRM1;MMP12 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MMP12 GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;PPARG;TRPV1;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;MMP12 20256:[DB14011 DB03729] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03729|2-Amino-5-Hydroxy-Benzimidazole PLAU common genes common pathways GO:0007165| signal transduction PLAU;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0042127| regulation of cell proliferation PLAU;PTGS2;PTGS1 GO:0043312| neutrophil degranulation PLAU;CAT;ALOX5 GO:0001666| response to hypoxia PLAU;CYP1A1;CHRNA7;CAT 20257:[DB14011 DB07270] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07270|N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE FBP1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;PPARG;TRPV4;TRPV1 GO:0030308| negative regulation of cell growth FBP1;PPARG GO:0008152| metabolic process ACAT1;FBP1;SMPD1 GO:0051289| protein homotetramerization FBP1;CAT;TRPV1;TRPM8;TRPA1;CRYZ 20258:[DB14011 DB04454] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;EGF;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation EGF;HTR2A GO:0001525| angiogenesis CYP1B1;EGF;PTGS2 GO:0043406| positive regulation of MAP kinase activity EGF;HTR2A GO:0010628| positive regulation of gene expression EGF;TRPV4 GO:0000187| activation of MAPK activity CHRNA7;SOD1;EGF;PLA2G1B GO:0043388| positive regulation of DNA binding EGF;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade EGF;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent EGF;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;EGF;HTR1A;HTR2A GO:0002576| platelet degranulation SOD1;EGF GO:0007611| learning or memory GATM;CNR1;CHRNA7 20259:[DB14011 DB02705] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02705|6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CACNA1I;PLA2G1B;PLAU;SMPD1;PPARG;GPR18 GO:0001666| response to hypoxia CHRNA7;CAT;PLAU;CYP1A1 GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0043312| neutrophil degranulation CAT;ALOX5;PLAU 20260:[DB14011 DB04775] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04775|Reidispongiolide C ACTA1 common genes common pathways GO:0048741| skeletal muscle fiber development ACTA1;GPX1 GO:0010628| positive regulation of gene expression TRPV4;ACTA1 GO:0006936| muscle contraction ACTA1;CACNA1H;GLRA1 GO:0009612| response to mechanical stimulus ACTA1;PPARG;TRPV4 GO:0010226| response to lithium ion ACTA1;PTGS2 20261:[DB14011 DB06080] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0046686| response to cadmium ion KIT;CAT GO:0000187| activation of MAPK activity KIT;CHRNA7;SOD1;PLA2G1B GO:0001541| ovarian follicle development SOD1;KIT GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7;FLT1 GO:0031532| actin cytoskeleton reorganization KIT;TRPV4 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;KDR;TRPV4;FLT4;CHRNA7;CSF1R;HTR2A;GPR55;HMGCR;OPRM1 GO:0010628| positive regulation of gene expression KIT;TRPV4 GO:0007283| spermatogenesis KIT;CNR1;SOD1 GO:0043406| positive regulation of MAP kinase activity FLT1;HTR2A;FLT3;KIT GO:0006687| glycosphingolipid metabolic process KIT;SMPD1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT;KIT;FLT3;FLT1 GO:0048514| blood vessel morphogenesis FLT1;FLT4;CYP1B1 GO:0031100| organ regeneration PPARG;FLT3 GO:0002376| immune system process CSF1R;IDO1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;KIT GO:0030224| monocyte differentiation CSF1R;PPARG GO:0010243| response to organic nitrogen TRPV1;PTGS2;FLT3 GO:0051897| positive regulation of protein kinase B signaling cascade KIT;GPX1 GO:0060326| cell chemotaxis KIT;ABCC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;KIT GO:0046330| positive regulation of JNK cascade TRPV4;FLT4 GO:0043066| negative regulation of apoptotic process FLT4;KDR;SOD1;HMGCR;PTGS2;CAT;CSF1R;GPX1 GO:0008284| positive regulation of cell proliferation KIT;CSF1R;CHRNA7;HMGCR;PTGS2;FLT1;FLT3;HTR2A;HTR1A;KDR;FLT4 GO:0045087| innate immune response CSF1R;PPARG GO:0008283| cell proliferation GPX1;CSF1R;HTR1A;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;CSF1R GO:0071345| cellular response to cytokine stimulus FLT3;CSF1R;TRPV1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;CSF1R;KIT GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0001934| positive regulation of protein phosphorylation FLT4;KDR;CSF1R;CHRNA7 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0016032| viral reproduction HTR2A;KDR;VDAC1 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;PTGS1;ALOX5;KIT;CSF1R GO:0030217| T cell differentiation GPR18;KIT GO:0008542| visual learning HMGCR;KIT GO:0048565| digestive tract development CYP1A1;KIT GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4;CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter KIT;PPARG GO:0001525| angiogenesis PTGS2;FLT1;CYP1B1;KDR;FLT4 GO:0035556| intracellular signal transduction KIT;PLA2G1B GO:0009314| response to radiation CAT;KIT;OPRM1;PTGS2 20262:[DB14011 DB00651] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;ADORA1;ADORA2A;GLRA1;TRPV1;GLRB GO:0035307| positive regulation of protein dephosphorylation ADORA1;SMPD1 GO:0042311| vasodilation ADORA2A;GPX1 GO:0043066| negative regulation of apoptotic process ADORA1;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0007626| locomotory behavior ADORA2A;OPRM1;SOD1 GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA1 GO:0042493| response to drug SMPD1;ABCC1;ADORA2A;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0030593| neutrophil chemotaxis PDE4D;PDE4B;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent PPARG;ADORA2A GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;ADORA1 GO:0050728| negative regulation of inflammatory response CNR2;ADORA1;ADORA2A GO:0007568| aging CYP1A1;CAT;PTGS2;HMGCR;PDE4D;NAPEPLD;CNR1;SOD1;HTR2A GO:0097756| PTGS2;HMGCR;ADORA1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;ADORA2A;PPARG;ADORA1;PDE7A;PDE4B;PDE4C;PDE7B;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;PDE4A;PDE4D;OPRM1;CNR2 GO:0006915| apoptotic process GPX1;VDAC1;ADORA2A GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0016042| lipid catabolic process DAGLA;PLA2G1B;ADORA1;NAPEPLD GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0031000| response to caffeine ADORA2A;PPARG GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;ADORA2A GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;ADORA1 GO:0045776| negative regulation of blood pressure ADORA1;CNR1 GO:0007399| nervous system development SMPD1;ADORA1;GLRB GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0001659| temperature homeostasis HTR2A;GPX1;ADORA1;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADORA2A;CNR1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2;GPX1 GO:0007268| synaptic transmission PDE7B;GLRB;VDAC1;GLRA1;CACNA1G;GLRA3;HTR2A;OPRM1;OPRD1 GO:0043524| negative regulation of neuron apoptosis SOD1;ADORA2A GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0007600| sensory perception TRPV2;OPRM1;ADORA2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;ADORA1;TRPV1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;IDO1;ALOX15;ADORA2A;ADORA1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADORA1;OPRD1;OPRM1 GO:0001975| response to amphetamine ADORA2A;SOD1;CNR2 GO:0050890| cognition ADORA1;CHRNA7 GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;PDE4A;PDE4D;OPRM1;CNR2;PDE7A;PDE4B;PDE4C;PDE7B;PLA2G1B;CACNA1I;GPR18;ADORA2A;PPARG;ADORA1;SMPD1 GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0045777| positive regulation of blood pressure CNR1;ADORA1 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;SOD1;OPRD1 GO:0051930| regulation of sensory perception of pain ADORA1;OPRM1;OPRD1 GO:0042755| eating behavior ADORA2A;OPRD1;OPRM1 GO:0032229| negative regulation of synaptic transmission, GABAergic ADORA1;CNR2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;ADORA1;PPARG;ADORA2A 20263:[DB14011 DB06230] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes OPRD1;OPRM1 common pathways GO:0009804| coumarin metabolic process CYP2D6;CYP1A1;UGT1A8 GO:0043278| response to morphine OPRK1;OPRM1;CNR1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0006631| fatty acid metabolic process ALOX15;UGT1A8;PTGS1;PTGS2 GO:0032094| response to food OPRM1;CYP1A1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;OPRK1;OPRM1;OPRD1;GLRA3 GO:0007626| locomotory behavior SOD1;OPRM1;OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;CYP1A1;IDO1 GO:0042060| wound healing ALOX15;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;GLRB;TRPV1;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0042220| response to cocaine CNR1;OPRM1;OPRK1;SMPD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;ALOX15 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;UGT1A8;CYP2C9;CYP1A1;UGT1A3;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;UGT1A8 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;OPRK1;GPR18;PPARG GO:0071363| cellular response to growth factor stimulus TRPV1;OPRD1;CAT GO:0038003| opioid receptor signaling pathway OPRD1;OPRM1;OPRK1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0006955| immune response OPRK1;CNR2;OPRD1 GO:0007600| sensory perception TRPV2;OPRM1;OPRK1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;OPRK1;GLRB;VDAC1;GLRA1;CACNA1G GO:0010629| negative regulation of gene expression OPRD1 GO:0008209| androgen metabolic process CYP3A4;UGT2B7 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0008152| metabolic process UGT1A3;ACAT1;UGT2B7;UGT1A8;SMPD1 GO:0009314| response to radiation OPRK1;CAT;OPRM1;PTGS2 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;UGT2B7;PTGS1;NAAA;GPX1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain TRPA1;OPRK1;TRPV1;CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1 GO:0045471| response to ethanol CAT;OPRM1;HMGCR;SOD1;CNR1;OPRK1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0042755| eating behavior OPRK1;OPRM1;OPRD1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0008344| adult locomotory behavior OPRD1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0032868| response to insulin stimulus TRPV4;OPRK1;AANAT;CAT GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0044849| OPRM1;OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007165| signal transduction OPRK1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0007610| behavior HTR1A;HTR2A;OPRK1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV4;TRPV1 GO:0071315| cellular response to morphine OPRM1 20264:[DB14011 DB06642] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06642|Bevasiranib VEGFA common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0001934| positive regulation of protein phosphorylation VEGFA;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;VEGFA GO:0007595| lactation SLC29A1;VEGFA GO:0048469| cell maturation PPARG;VEGFA GO:0001525| angiogenesis VEGFA;PTGS2;CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0007399| nervous system development VEGFA;SMPD1;GLRB GO:0051781| positive regulation of cell division VEGFA;CAT GO:0043117| positive regulation of vascular permeability TRPV4;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2;OPRD1 GO:0030224| monocyte differentiation PPARG;VEGFA GO:0030324| lung development VEGFA;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;VEGFA GO:0001822| kidney development CAT;VEGFA GO:0043066| negative regulation of apoptotic process PTGS2;VEGFA;HMGCR;SOD1;GPX1;CAT GO:0002576| platelet degranulation VEGFA;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;VEGFA GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0030855| epithelial cell differentiation VDAC1;PPARG;VEGFA GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;VEGFA GO:0001541| ovarian follicle development VEGFA;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;VEGFA;HMGCR;ALOX15;TRPV4 GO:0043406| positive regulation of MAP kinase activity VEGFA;HTR2A GO:0010628| positive regulation of gene expression VEGFA;TRPV4 GO:0001666| response to hypoxia CYP1A1;VEGFA;CHRNA7;CAT GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;VEGFA;PTGS2 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 20265:[DB14011 DB11182] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways GO:0006879| cellular iron ion homeostasis TF;SOD1;ABCG2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;IDO1;ALOX15;LYZ;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;LTF;CAT GO:0001503| ossification ALOX15;LTF GO:0008152| metabolic process ACAT1;SMPD1;LYZ GO:0006351| transcription, DNA-dependent PPARG;LTF GO:0061844| LTF;PLA2G1B GO:0001895| retina homeostasis TF;SOD1;LTF;LYZ;ALB GO:0006811| ion transport TF;TRPV3;CACNA1H;GLRA3;TRPV2;LTF;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8 GO:0002227| innate immune response in mucosa PLA2G1B;LTF GO:0019731| antibacterial humoral response PLA2G1B;LTF GO:0006355| regulation of transcription, DNA-dependent PPARG;LTF GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B;LTF GO:0045087| innate immune response PPARG;LTF GO:0043312| neutrophil degranulation LTF;CAT;ALOX5;LYZ GO:0002576| platelet degranulation TF;SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;LTF;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0002376| immune system process LTF;IDO1 GO:0098869| ALB;GSR;PTGS2;CAT;GPX1;PTGS1 20266:[DB14011 DB08708] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08708|N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine PIM1 common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;PIM1;HTR1A GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PIM1;PTGS2;SOD1 GO:0006915| apoptotic process GPX1;PIM1;VDAC1 20267:[DB14011 DB07482] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0001666| response to hypoxia CYP1A1;DPP4;CAT;CHRNA7 20268:[DB14011 DB03940] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03940|Oxamic Acid LDHA;LDHB;SLC16A3 common genes common pathways GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;TRPA1;LDHA GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;LDHA;PPARG GO:0007584| response to nutrient LDHA;PPARG;HMGCR;CNR1 GO:0043627| response to estrogen stimulus LDHA;PPARG GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;LDHA;TRPA1;CYP1A1;PPARG GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;LDHA;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;LDHB;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;LDHA;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0001666| response to hypoxia CYP1A1;LDHA;CHRNA7;CAT GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;SLC16A3;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2 GO:0051591| response to cAMP LDHA;AANAT 20269:[DB14011 DB04770] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;PDXK;HTR1A GO:0043312| neutrophil degranulation PDXK;CAT;ALOX5 20270:[DB14011 DB06709] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06709|Methacholine CHRM3 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CHRM3;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0007399| nervous system development GLRB;CHRM3;SMPD1 GO:0008283| cell proliferation GPX1;HTR1A;CHRM3;CYP1A1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CHRM3;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0006939| smooth muscle contraction HTR2A;CHRM3 20271:[DB14011 DB04014] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04014|Alsterpaullone CDK5;CDK1;GSK3B common genes common pathways GO:0042542| response to hydrogen peroxide SOD1;CDK1;CAT;GPX1;TRPA1 GO:0048148| behavioral response to cocaine CDK5;HTR2A GO:0035556| intracellular signal transduction GSK3B;PLA2G1B GO:0007399| nervous system development CDK5;SMPD1;GLRB;GSK3B GO:0060078| regulation of postsynaptic membrane potential CDK5;CHRNA7 GO:0045471| response to ethanol CAT;CDK1;HMGCR;OPRM1;CNR1;SOD1 GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1;TRPV1;TRPA1;CDK5 GO:0048678| response to axon injury CDK1;SOD1 GO:0008542| visual learning CDK5;HMGCR GO:0007268| synaptic transmission CACNA1G;CDK5;GLRA1;GLRB;VDAC1;OPRM1;OPRD1;HTR2A;GLRA3 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CDK5;CACNA1G;CACNA1I GO:0046718| entry of virus into host cell HTR2A;CDK1 GO:0051966| regulation of synaptic transmission, glutamatergic CDK5;CNR1 GO:0045740| positive regulation of DNA replication PLA2G1B;CDK1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;CDK1 GO:0014823| response to activity CDK1;CAT GO:0008283| cell proliferation GPX1;CDK1;HTR1A;CDK5;CYP1A1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CDK1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0009636| response to toxin CDK1;GPX1;CAT;CYP1A1;CYP1B1 GO:0045786| negative regulation of cell cycle PTGS2;CDK5 GO:0043066| negative regulation of apoptotic process GPX1;GSK3B;CAT;HMGCR;CDK1;PTGS2;SOD1 GO:0007623| circadian rhythm GSK3B;AANAT GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;CDK5;GLRB;TRPV1;GLRA3;OPRM1;GSK3B;CHRNA7;SLC29A1 GO:0070509| calcium ion import CACNA1G;CDK5;CACNA1I;TRPV4;CACNA1H GO:0010243| response to organic nitrogen PTGS2;CDK1;TRPV1 GO:0006367| transcription initiation from RNA polymerase II promoter CDK1;PPARG GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CDK1;CYP1A2;PTGS2 GO:0007569| cell aging SOD1;CDK1 GO:0031100| organ regeneration CDK1;PPARG GO:0009611| response to wounding GPX1;CDK5;CYP1A1 GO:0010468| regulation of gene expression CYP1A2;CDK1 GO:0046688| response to copper ion AANAT;SOD1;CDK1 GO:0010628| positive regulation of gene expression GSK3B;CDK1;TRPV4 GO:0048511| rhythmic process PPARG;CDK5;AANAT;GSK3B GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CDK5 GO:0046686| response to cadmium ion CDK1;CAT GO:0006915| apoptotic process GPX1;CDK1;VDAC1;CDK5 GO:0030855| epithelial cell differentiation PPARG;VDAC1;CDK1 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;CDK5 GO:0000187| activation of MAPK activity CHRNA7;CDK1;SOD1;PLA2G1B 20272:[DB14011 DB02532] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02532|2,4,6-Triaminoquinazoline DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;CYP1A2;DHRS4L1;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5 20273:[DB14011 DB06813] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06813|Pralatrexate DHFR;TYMS;FPGS;SLC19A1 common genes common pathways GO:0007623| circadian rhythm AANAT;TYMS GO:0032259| methylation TYMS;CYP1A2 GO:0034097| response to cytokine stimulus TYMS;PTGS2;AANAT GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TYMS;TRPA1;ABCG2 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP2C9;CYP1A1;DHFR;CRYZ GO:0033189| response to vitamin A CYP1A1;TYMS;PPARG;CAT GO:0007568| aging CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT;TYMS;CYP1A1 GO:0031100| organ regeneration FPGS;PPARG GO:0001889| liver development ACAT1;FPGS;CYP1A1 GO:0045471| response to ethanol TYMS;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0007420| brain development FPGS;ACAT1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TYMS;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin GPX1;CAT;CYP1B1;CYP1A1;TYMS GO:0008283| cell proliferation CYP1A1;FPGS;GPX1;HTR1A GO:0006139| nucleobase-containing compound metabolic process FPGS;SLC29A1 GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS 20274:[DB14011 DB08339] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways GO:0042127| regulation of cell proliferation ABL1;PTGS1;PTGS2 GO:0034599| cellular response to oxidative stress GPX1;CAT;SOD1;ABL1;GSR GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0045087| innate immune response PPARG;ABL1 GO:0007155| cell adhesion CYP1B1;ABL1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0048538| thymus development SOD1;ABL1 GO:0006979| response to oxidative stress ABL1;SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;ABL1;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0006915| apoptotic process GPX1;ABL1;VDAC1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;ABL1;SMPD1;PPARG GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ABL1 GO:0007204| elevation of cytosolic calcium ion concentration ABL1;TRPV4;TRPV1;HTR2A;OPRM1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ABL1 20275:[DB14011 DB05362] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05362|SSR-126517E F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 20276:[DB14011 DB05069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways GO:0006812| cation transport CHRNA9;TRPM8 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H;TRPM8;CHRNA10;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;GLRA1;TRPA1;CHRNA9;CACNA1G GO:0070588| calcium ion transmembrane transport CACNA1G;CHRNA9;TRPA1;TRPV1;CACNA1I;TRPV4;CHRNA10;TRPM8;OPRM1;CACNA1H;TRPV3;TRPV2;CHRNA7 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;CHRNA9;PPARG;CHRNA10;PLA2G1B;CACNA1I GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;CHRNA9;CHRNA10;TRPV1;TRPV4 GO:0006816| calcium ion transport TRPM8;TRPV4;CACNA1I;TRPV1;CHRNA10;CHRNA9;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;TRPV3 GO:0060078| regulation of postsynaptic membrane potential CHRNA10;CHRNA9;CHRNA7 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;CHRNA9;CHRNA10;TRPV1;GLRB GO:0007605| sensory perception of sound SOD1;GPX1;CHRNA9 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;CHRNA10 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;CHRNA9;CHRNA10;GLRB;TRPV1;GLRA3;OPRM1;CHRNA7;SLC29A1 20277:[DB14011 DB02243] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02243|4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide CTSF common genes common pathways 20278:[DB14011 DB14007] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14007|Pentetic acid SERPINA1 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;SERPINA1 GO:0002576| platelet degranulation SERPINA1;SOD1 20279:[DB14011 DB08526] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08526|CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE CTSH common genes common pathways GO:0006919| activation of caspase activity CTSH;PPARG GO:0010628| positive regulation of gene expression CTSH;TRPV4 GO:0006915| apoptotic process GPX1;VDAC1;CTSH GO:0045766| positive regulation of angiogenesis CTSH;CYP1B1;CHRNA7 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;CTSH GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;CTSH GO:0043312| neutrophil degranulation ALOX5;CAT;CTSH GO:0032526| response to retinoic acid CTSH;PPARG 20280:[DB14011 DB06956] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06956|N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;HSP90AA1 GO:0009409| response to cold TRPM8;HSP90AA1;PPARG;TRPA1 GO:0009408| response to heat HSP90AA1;TRPV1;TRPV3;SOD1;TRPV2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;HSP90AA1;PTGS2;OPRM1 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 20281:[DB14011 DB06229] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes HTR2A common pathways GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger DRD2;HTR2C;GPR18;GPR55 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0009416| response to light stimulus DRD2;AANAT GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2B;HTR2A GO:0001666| response to hypoxia CAT;CHRNA7;DRD2;CYP1A1 GO:0007202| activation of phospholipase C activity ADRA1A;HTR2B;HTR2A;GPR55 GO:0008219| cell death HTR2A GO:0006915| apoptotic process ADRA1A;VDAC1;GPX1 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;DRD2 GO:0000187| activation of MAPK activity CHRNA7;SOD1;ADRA2B;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;HTR2C;HTR2B;DRD2;ADRA1A;TRPV4 GO:0071502| cellular response to temperature stimulus HTR2B;TRPV1 GO:0007210| serotonin receptor signaling pathway HTR2C;HTR2B;HTR1A;HTR2A GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;DRD2;TRPV4;TRPM8;HTR2C;HTR2B GO:0042593| glucose homeostasis CNR1;ADRA1B;PPARG;TRPV4;ADRA2A GO:0007568| aging PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CAT;CYP1A1;ADRA1A GO:0007186| G-protein coupled receptor signaling pathway ADRA1D;PPARG;GPR18;DRD2;ADRA1A;HTR2C;HTR2B;ADRA2A;OPRM1;CNR2;OPRD1;HRH1;GPR55;HTR1A;ADRA2C;ADRA2B;GPR12;CNR1;HTR2A;ADRA1B GO:0051209| release of sequestered calcium ion into cytosol HTR2C;HTR2B;DRD2;TRPV1;TRPA1;HTR2A GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0035094| response to nicotine CNR1;CHRNA7;DRD2 GO:0043278| response to morphine DRD2;CNR1;OPRM1 GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2A;HTR2B;HTR2C GO:0044380| protein localization to cytoskeleton HTR2A GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ADRA1A;DRD2;ABCG2;HTR2B;HTR2C GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0050795| regulation of behavior HTR2A;HTR1A;HTR2B GO:0007628| adult walking behavior DRD2;GLRB;GLRA1 GO:0043066| negative regulation of apoptotic process HTR2B;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0008284| positive regulation of cell proliferation ADRA1D;HTR2B;ADRA2A;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;PPARG GO:0007626| locomotory behavior DRD2;HTR2C;OPRM1;SOD1 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0014824| artery smooth muscle contraction HTR2A GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;DRD2;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1D;HTR2C;HTR2B;ADRA1A;HTR2A;OPRM1;HRH1;OPRD1;ADRA1B GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;DRD2;ADRA1A;CYP1B1;PPARG GO:0001662| behavioral fear response HTR1A;HTR2C;VDAC1 GO:0046883| regulation of hormone secretion HTR1A;HTR2A GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1D;ADRA1A GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2C;HTR2A GO:0051781| positive regulation of cell division CAT;HTR2B GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0045777| positive regulation of blood pressure ADRA2B;CNR1 GO:0014854| response to inactivity DRD2;CAT GO:0043267| negative regulation of potassium ion transport HTR2A GO:0009636| response to toxin GPX1;CAT;CYP1B1;DRD2;CYP1A1 GO:0007270| neuron-neuron synaptic transmission DRD2;VDAC1 GO:0008283| cell proliferation ADRA1D;CYP1A1;GPX1;ADRA1B;HTR1A GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADRA2C GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0007610| behavior HTR2C;HTR2B;HTR1A;HTR2A GO:0007165| signal transduction ADRA1D;SMPD1;PPARG;GPR18;ADRA1A;DRD2;CACNA1I;PLA2G1B;ADRA2A;HTR2B;HTR2C;CNR2;OPRM1;HRH1;OPRD1;ADRA2C;GPR55;HTR1A;ADRA2B;HTR2A;GPR12;CNR1;ADRA1B;CHRNA7 GO:0045907| positive regulation of vasoconstriction ADRA1B;HRH1;PTGS2;HTR2A;ADRA2C;ADRA1A;ADRA1D GO:1900273| CHRNA7;DRD2 GO:0001819| positive regulation of cytokine production SOD1;HTR2B;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H GO:0050482| arachidonic acid secretion DRD2;PLA2G1B GO:0006939| smooth muscle contraction ADRA1A;HTR2B;HTR2A GO:0014065| phosphatidylinositol 3-kinase cascade HTR2B;HTR2A GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADRA2A;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1B;HTR2A;OPRM1;TRPV4;ADRA1A;TRPV1;ADRA1D GO:0050796| regulation of insulin secretion ADRA2C;CNR1;ADRA2A GO:0007613| memory CHRNA7;HTR2A;CNR1;HRH1;PTGS2 GO:0001975| response to amphetamine DRD2;CNR2;SOD1 GO:0046718| entry of virus into host cell HTR2A GO:0008542| visual learning DRD2;HMGCR;HRH1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0033674| positive regulation of kinase activity HTR2A GO:0016032| viral reproduction HTR2A;VDAC1 GO:0001964| startle response GLRB;DRD2;GLRA1 GO:0006954| inflammatory response ALOX5;PTGS1;HRH1;CNR2;PTGS2;IDO1;ALOX15;TRPV1 GO:0007565| female pregnancy ADRA2B;ADRA2C;IDO1 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0007268| synaptic transmission GLRB;VDAC1;HTR2C;CACNA1G;GLRA1;OPRD1;OPRM1;HTR2A;GLRA3 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain TRPA1;HTR2A GO:0002027| regulation of heart rate CACNA1G;DRD2 GO:0007507| heart development HTR2B;PPARG GO:0048148| behavioral response to cocaine DRD2;HTR2A GO:0035556| intracellular signal transduction ADRA1B;PLA2G1B;DRD2;ADRA1A GO:0042310| vasoconstriction HTR1A;HTR2B GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;ADRA1D;ADRA1B;CNR1 GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A;HTR2C GO:0001659| temperature homeostasis DRD2;TRPV1;GPX1;HTR2A GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;TRPA1;TRPV1 GO:0048678| response to axon injury SOD1;DRD2 GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0045471| response to ethanol DRD2;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0045821| positive regulation of glycolysis HTR2A GO:0045776| negative regulation of blood pressure CNR1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity DRD2;OPRM1 20282:[DB14011 DB04018] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04018|S-Isopropyl-Isothiourea NOS3 common genes common pathways GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat NOS3;TRPV1;SOD1;TRPV3;TRPV2 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0001525| angiogenesis CYP1B1;NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation CYP1B1;NOS3;PPARG;PTGS2;OPRM1 GO:0008217| regulation of blood pressure PPARG;NOS3;PTGS2;SOD1;PTGS1 GO:1902042| GPX1;NOS3 GO:0006809| nitric oxide biosynthetic process NOS3;CYP1B1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0045454| cell redox homeostasis GPX1;NOS3;GSR GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;NOS3;CYP1A1;CYP2C9;CRYZ GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0042311| vasodilation GPX1;NOS3 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:0030324| lung development NOS3;CYP1A2 GO:0045766| positive regulation of angiogenesis CHRNA7;NOS3;CYP1B1 20283:[DB14011 DB02551] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02551|6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;PLAU;CACNA1I;PLA2G1B GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0043312| neutrophil degranulation CAT;ALOX5;PLAU GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;PLAU 20284:[DB14011 DB05630] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05630|Sodium stibogluconate TOP1 common genes common pathways GO:0048511| rhythmic process PPARG;TOP1;AANAT GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;TOP1;CAT GO:0007623| circadian rhythm AANAT;TOP1 GO:0016032| viral reproduction HTR2A;TOP1;VDAC1 20285:[DB14011 DB07056] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07056|2-(6-{[(3-chloro-2-methylphenyl)sulfonyl]amino}pyridin-2-yl)-N,N-diethylacetamide HSD11B1 common genes common pathways GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B1 GO:0008202| steroid metabolic process HSD11B1;CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0030324| lung development CYP1A2;HSD11B1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;HSD11B1;CAT GO:0006629| lipid metabolic process PPARG;CYP2C9;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR;HSD11B1;NAAA;GPX1;PTGS1 20286:[DB14011 DB02527] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;HCN2;CACNA1H GO:0098656| SLC22A6;VDAC1;SLC22A8;SLC22A7 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;GPX1;CAT GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;AANAT;ACAT1;ABCC4;PTGS2;CYP1A2 GO:0006811| ion transport TRPV2;SLC22A7;CHRNA7;CACNA1H;TRPV3;GLRA3;SLC22A8;HCN2;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0035556| intracellular signal transduction PRKAR2B;PLA2G1B;PRKAR1A GO:0007507| heart development PRKAR1A;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;PRKAR1A GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;HCN2;CACNA1H GO:0045859| regulation of protein kinase activity PRKAR1A;PRKAR2B;SOD1 GO:0071320| cellular response to cAMP AANAT;HCN2 GO:0042391| regulation of membrane potential HCN2;CACNA1H;GLRA1;CACNA1G;GLRB GO:0051260| protein homooligomerization GLRA1;SLC22A6;ACAT1;GLRA3 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0006810| transport TRPV2;CACNA1I;TRPV1;ABCC5;ABCG2;ABCC1 GO:0010033| response to organic substance ABCC4;PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0055085| transmembrane transport SLC22A6;CACNA1G;ABCC1;TRPA1;TRPV1;CACNA1I;TRPV4;VDAC1;ABCC11;ABCG2;TRPM8;ABCC5;CACNA1H;TRPV3;HCN2;SLC22A8;TRPV2;ABCC4;SLC22A7 GO:0002576| platelet degranulation SOD1;ABCC4 GO:0007612| learning PRKAR2B;VDAC1;PTGS2 GO:0097332| SOD1;PRKAR2B GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;ABCC4 GO:0010243| response to organic nitrogen PTGS2;ABCC4;TRPV1 GO:0099133| ABCC1;ABCC11;ABCC5;ABCC4 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15;PRKAR2B GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;ABCC4;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0055114| oxidation-reduction process CAT;ABCC4;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 20287:[DB14011 DB03536] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03536|Benzoyl-Arginine-Alanine-Methyl Ketone CTSF common genes common pathways 20288:[DB14011 DB07954] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0002027| regulation of heart rate CACNA1G;PDE4D GO:0071260| cellular response to mechanical stimulus PDE2A;PTGS2 GO:0008152| metabolic process PDE5A;PDE2A;SMPD1;ACAT1 GO:0001525| angiogenesis PDE3B;PTGS2;CYP1B1 GO:0043951| negative regulation of cAMP-mediated signaling PDE3B;OPRM1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;PDE8A GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0007165| signal transduction PDE4D;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;PDE3B;CHRNA7;PDE2A;SMPD1;PDE8A;PDE5A;GPR18;PPARG;CACNA1I;PLA2G1B;PDE7A;PDE9A GO:0070588| calcium ion transmembrane transport TRPA1;PDE2A;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;TRPV3;OPRM1;CACNA1H;CHRNA7;TRPV2 GO:0006939| smooth muscle contraction HTR2A;PDE4D GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PDE3B GO:0043117| positive regulation of vascular permeability TRPV4;PDE2A GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1;PDE6G GO:0050729| positive regulation of inflammatory response PDE2A;TRPV4 GO:0050896| response to stimulus TRPM8;TRPA1;PDE6G GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PDE2A;TRPV4;TRPV1 GO:0016525| negative regulation of angiogenesis PDE3B;PPARG GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1;PDE3B GO:0030224| monocyte differentiation PDE2A;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;PDE8A GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B GO:0007568| aging CYP1A1;CAT;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;PDE4D;HMGCR GO:0007186| G-protein coupled receptor signaling pathway PDE7A;PDE2A;PDE8A;GPR18;PPARG;PDE3B;OPRD1;PDE4D;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0043406| positive regulation of MAP kinase activity HTR2A;PDE5A GO:0042130| negative regulation of T cell proliferation PDE5A;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;PDE8A;TRPV4;ALOX15 GO:0000187| activation of MAPK activity PLA2G1B;PDE6G;CHRNA7;SOD1 20289:[DB14011 DB04795] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04795|Thenoyltrifluoroacetone CES1;SDHA common genes common pathways GO:0007399| nervous system development GLRB;SMPD1;SDHA GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CES1;CYP3A4 GO:0008152| metabolic process SMPD1;CES1;ACAT1 GO:0009636| response to toxin CYP1A1;CYP1B1;CES1;GPX1;CAT GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;SDHA;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5 GO:0022900| electron transport chain IDO1;GSR;CYP1A2;SDHA GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0030855| epithelial cell differentiation CES1;VDAC1;PPARG 20290:[DB14011 DB11363] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes ABCG2 common pathways GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;ALK;SOD1 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;TRPV1;TRPV4;ABCB1;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0036269| IDO1;ALK GO:0006810| transport ABCC1;ABCB1;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0015886| heme transport ABCG2 GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0033344| cholesterol efflux ABCG2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ALK GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0008283| cell proliferation ALK;HTR1A;GPX1;CYP1A1 GO:0007420| brain development ALK;ACAT1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;ALK;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;ALK GO:0046415| urate metabolic process ABCG2 GO:0007399| nervous system development GLRB;SMPD1;ALK 20291:[DB14011 DB05168] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways GO:0043312| neutrophil degranulation FOLR3;CAT;ALOX5 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;FOLR2 GO:0048678| response to axon injury FOLR1;SOD1 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;FOLR2;ALOX5;PTGS1;CNR2;PTGS2 20292:[DB14011 DB08889] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCB1;ABCG2 GO:0045444| fat cell differentiation PSMB8;GPX1 GO:0010243| response to organic nitrogen TRPV1;PTGS2;PSMB2 GO:0043312| neutrophil degranulation ALOX5;CAT;PSMB1 GO:0055085| transmembrane transport PSMB1;TRPV3;CACNA1H;PSMB5;PSMB9;PSMB2;PSMB10;TRPV2;ABCC1;CACNA1G;TRPA1;PSMB8;TRPV4;ABCB1;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2 GO:0006810| transport TRPV2;ABCB1;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PSMB5;PTGS2 GO:0002376| immune system process IDO1;PSMB8;PSMB10;PSMB9 GO:0016032| viral reproduction PSMB5;PSMB1;PSMB2;HTR2A;PSMB9;PSMB10;PSMB8;VDAC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;PSMB2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 20293:[DB14011 DB00984] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0007283| spermatogenesis AR;CNR1;SOD1 GO:0010628| positive regulation of gene expression TRPV4;AR GO:0006810| transport AR;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0010468| regulation of gene expression CYP1A2;AR GO:0055114| oxidation-reduction process IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;CYP19A1;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0022900| electron transport chain CYP1A2;CYP19A1;IDO1;GSR GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0006694| steroid biosynthetic process HMGCR;CYP19A1;CYP17A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;AR GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0007548| sex differentiation CYP17A1;AR GO:0008283| cell proliferation AR;GPX1;HTR1A;CYP1A1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;AR;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1 20294:[DB14011 DB11605] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes CYP3A7;CYP3A5;CYP3A4 common pathways GO:0002933| CYP3A5;CYP1A1;CYP3A7;CYP3A4 GO:0007043| cell-cell junction assembly TRPV4;NR1H4 GO:0036378| CYP3A4 GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0001666| response to hypoxia CYP1A1;PPARA;CHRNA7;CAT GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;NR1I2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;NR1I2;CYP2C9;CYP1A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0032720| negative regulation of tumor necrosis factor production NR1H4;CHRNA7;GPR18 GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0002376| immune system process NR1H4;IDO1 GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1;NR1H4 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;NR1I2;PPARG GO:0006631| fatty acid metabolic process PPARA;PTGS2;PTGS1;ALOX15 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2;PPARA;NR1H4 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP3A43;ALOX5;GPX1;PTGS1;CAT GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0050728| negative regulation of inflammatory response NR1H4;CNR2;PPARA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2;NR1H4;PPARA GO:0042060| wound healing OPRM1;PPARA;ALOX15 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;NR1H4;HMGCR;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR1I2;NR1H4;PPARA GO:0045087| innate immune response NR1H4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;NR1H4;PPARA GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;NR1H4;CYP1B1 GO:0032868| response to insulin stimulus PPARA;CAT;AANAT;TRPV4 GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1;PPARA GO:0042908| xenobiotic transport ABCC1;NR1I2;ABCG2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;NR1I2;SMPD1;CHRNA7;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;NR1H4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;NR1I2;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process CYP3A4 GO:0006954| inflammatory response CNR2;PTGS2;NR1H4;PTGS1;ALOX5;ALOX15;IDO1;TRPV1 GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0006357| regulation of transcription from RNA polymerase II promoter NR1H4;PPARG GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0006351| transcription, DNA-dependent NR1H4;PPARA;PPARG;NR1I2 GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG;PPARA;NR1H4 GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0006805| xenobiotic metabolic process NR1I2;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARA;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;NAAA;GPX1;PTGS1 GO:0007507| heart development PPARA;PPARG 20295:[DB14011 DB08602] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;PDE7A;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PDE7A;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 20296:[DB14011 DB06728] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways GO:0010193| response to ozone CAT;CYP2E1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;HMGCR;CYP3A7;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1B1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 GO:0042493| response to drug CAT;HTR2A;SOD1;CYP2E1;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;CYP2E1;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1 GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0002576| platelet degranulation SOD1;ALB GO:0001895| retina homeostasis ALB;SOD1 GO:0006641| triglyceride metabolic process GPX1;CAT;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0045471| response to ethanol CAT;CYP2E1;CNR1;SOD1;OPRM1;HMGCR 20297:[DB14011 DB00522] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00522|Bentiromide HPN common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;HPN GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;HPN 20298:[DB14011 DB02004] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways GO:0001666| response to hypoxia DPP4;CYP1A1;CHRNA7;CAT GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;DPP4 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell HTR2A;DPP4 20299:[DB14011 DB09301] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PTGS2;VEGFA;SLC29A1 GO:0010468| regulation of gene expression GDNF;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PPARG;CCL2;GPR18 GO:0006687| glycosphingolipid metabolic process SMPD1;ARSB;HEXB GO:0007605| sensory perception of sound SOD1;GPX1;HEXB GO:0032793| positive regulation of CREB transcription factor activity OPRD1;VEGFA GO:0006874| cellular calcium ion homeostasis CHRNA7;HEXB;GPR12;HTR2A;TRPV4;TRPM8 GO:0070374| positive regulation of ERK1 and ERK2 cascade CCL2;TRPV4;ALOX15;OPRM1;VEGFA;HMGCR;GPR55;HTR2A;CHRNA7 GO:0030855| epithelial cell differentiation VDAC1;PPARG;VEGFA GO:0001541| ovarian follicle development SOD1;VEGFA GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;VEGFA GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;OPRM1;CNR2;CCL2 GO:0043406| positive regulation of MAP kinase activity HTR2A;VEGFA GO:0071356| cellular response to tumor necrosis factor TRPV1;CCL2 GO:0001657| ureteric bud development CAT;GDNF GO:0001666| response to hypoxia CYP1A1;VEGFA;CAT;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;VEGFA GO:0030324| lung development CYP1A2;VEGFA GO:0000122| negative regulation of transcription from RNA polymerase II promoter VEGFA;PPARG;TRPV1;TRPV4 GO:0007155| cell adhesion CYP1B1;CCL2 GO:0043312| neutrophil degranulation GALNS;ARSB;GUSB;ALOX5;HEXB;CAT GO:0002576| platelet degranulation SOD1;VEGFA GO:0008284| positive regulation of cell proliferation GDNF;CHRNA7;PTGS2;VEGFA;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GDNF;HEXB;VEGFA;PLA2G1B;PPARG GO:0007626| locomotory behavior OPRM1;SOD1;HEXB GO:0001822| kidney development VEGFA;CAT GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;VEGFA;SOD1;GPX1;GDNF;CAT GO:0030224| monocyte differentiation PPARG;VEGFA GO:0050905| neuromuscular process GLRA1;GLRB;HEXB GO:0030593| neutrophil chemotaxis PLA2G1B;CCL2 GO:0071407| cellular response to organic cyclic compound CYP1B1;CCL2;CYP1A1 GO:0043117| positive regulation of vascular permeability TRPV4;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2;OPRD1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;GDNF;CHRNA7;SMPD1;PPARG;CCL2;GPR18;CACNA1I;PLA2G1B GO:0008344| adult locomotory behavior GDNF;OPRD1 GO:0090280| positive regulation of calcium ion import CCL2;TRPV2;TRPV3 GO:0043627| response to estrogen stimulus PPARG;ARSB GO:0007584| response to nutrient HMGCR;CNR1;ARSB;PPARG GO:0051781| positive regulation of cell division VEGFA;CAT GO:0001525| angiogenesis VEGFA;PTGS2;CYP1B1;CCL2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CCL2;TRPV1 GO:0048469| cell maturation PPARG;VEGFA GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0007399| nervous system development SMPD1;GLRB;BDNF;VEGFA;GDNF GO:0008152| metabolic process IDS;ARSB;GALNS;GUSB;HEXB;ACAT1;SMPD1;IDUA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0001934| positive regulation of protein phosphorylation VEGFA;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0043524| negative regulation of neuron apoptosis CCL2;BDNF;SOD1;GDNF GO:0007595| lactation SLC29A1;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A GO:0009268| response to pH ARSB;TRPV1 GO:0010976| positive regulation of neuron projection development CNR1;ARSB GO:0006954| inflammatory response CCL2;IDO1;ALOX15;TRPV1;CNR2;PTGS2;PTGS1;ALOX5 GO:0006955| immune response OPRD1;CNR2;CCL2 20300:[DB14011 DB08771] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08771|(5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0006629| lipid metabolic process HSD11B1;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;HSD11B1;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19 GO:0030324| lung development HSD11B1;CYP1A2 GO:0006704| glucocorticoid biosynthetic process HSD11B1;CYP17A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;HSD11B1;CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1 20301:[DB14011 DB05047] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways GO:0006810| transport TRPV1;CACNA1I;ABCG2;GRIA4;ABCC1;TRPV2;GRIA3 GO:0034220| ion transmembrane transport GRIA2;CHRNA7;GRIA3;GLRA3;TRPV1;GLRB;GRIA1;GRIA4;TRPA1;GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;GRIA2;CHRNA7;OPRM1;GRIA3;GLRA3;GRIA1;TRPV1;GLRB;GRIA4;GLRA1 GO:0007165| signal transduction GRIA2;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;GRIA1;SMPD1;PPARG;GPR18 GO:0006811| ion transport CHRNA7;TRPV2;GRIA2;GLRA3;CACNA1H;GRIA3;TRPV3;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;GRIA1;GLRA1;TRPA1;CACNA1G;GRIA4 GO:0007399| nervous system development SMPD1;GLRB;BDNF GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GRIA1 GO:0043524| negative regulation of neuron apoptosis BDNF;SOD1 GO:0007268| synaptic transmission GRIA2;GLRA3;HTR2A;OPRD1;OPRM1;GRIA1;GLRB;VDAC1;GLRA1;CACNA1G 20302:[DB14011 DB07614] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways GO:0019371| cyclooxygenase pathway PTGS2;PTGS1;HPGDS GO:0006693| prostaglandin metabolic process HPGDS;PTGS1;PTGS2 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;HPGDS;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS;PTGS1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1;HPGDS GO:0007165| signal transduction GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;HPGDS;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1;HPGDS GO:0007626| locomotory behavior HPGDS;SOD1;OPRM1 20303:[DB14011 DB07838] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07838|(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE NMT2 common genes common pathways 20304:[DB14011 DB00876] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1;ABCC2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;AGTR1;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0006810| transport TRPV2;ABCC1;CACNA1I;TRPV1;ABCG2;ABCC2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger AGTR1;GPR55;GPR18 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;ABCC1;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;ABCC2 GO:0001822| kidney development AGTR1;CAT GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;ABCC2;CYP1A1 GO:0042127| regulation of cell proliferation AGTR1;PTGS1;PTGS2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;HTR2A;AGTR1 GO:0060326| cell chemotaxis AGTR1;ABCC1 GO:0099133| ABCC1;ABCC2 GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;ABCC2 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0007165| signal transduction AGTR1;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0050729| positive regulation of inflammatory response TRPV4;AGTR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;AGTR1;HTR2A;OPRM1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCC1 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0009408| response to heat ABCC2;TRPV1;SOD1;TRPV3;TRPV2 GO:0007565| female pregnancy IDO1;ABCC2 20305:[DB14011 DB07636] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07636|5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE MT-CYB;UQCRFS1;CYC1;UQCRB;UQCR10 common genes common pathways GO:0009408| response to heat SOD1;TRPV3;TRPV2;MT-CYB;TRPV1 GO:0045471| response to ethanol MT-CYB;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0051592| response to calcium ion MT-CYB;AANAT GO:0014070| response to organic cyclic compound PPARG;CYP1A1;MT-CYB;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0009636| response to toxin MT-CYB;CYP1A1;CYP1B1;CAT;GPX1 GO:0007584| response to nutrient PPARG;MT-CYB;HMGCR;CNR1 GO:0009725| response to hormone stimulus UQCRFS1;ACAT1;MT-CYB GO:0055114| oxidation-reduction process CYC1;CRYZ;CYP1A1;CYP2C9;MT-CYB;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;UQCRB;CYP3A5;ALOX15;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;UQCRFS1;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;UQCR10;CAT GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;UQCRFS1;ABCG2;ABCC1;SMPD1;TRPA1;MT-CYB;PPARG;CYP1A1 GO:0010243| response to organic nitrogen TRPV1;MT-CYB;PTGS2 GO:0055093| response to hyperoxia CAT;MT-CYB;CYP1A1 GO:0046677| response to antibiotic CYP1A1;SOD1;UQCRFS1 GO:0042538| hyperosmotic salinity response MT-CYB;TRPV4 GO:0046686| response to cadmium ion MT-CYB;CAT GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;MT-CYB GO:0046688| response to copper ion AANAT;SOD1;MT-CYB GO:0009060| aerobic respiration CAT;UQCR10;UQCRB GO:0031100| organ regeneration MT-CYB;PPARG 20306:[DB14011 DB03955] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03955|1-deoxymannojirimycin MAN2A1 common genes common pathways GO:0050769| positive regulation of neurogenesis MAN2A1;OPRM1 GO:0008152| metabolic process ACAT1;SMPD1;MAN2A1 GO:0001889| liver development ACAT1;MAN2A1;CYP1A1 20307:[DB14011 DB01414] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways GO:0051260| protein homooligomerization SLC22A6;GLRA1;GLRA3;ACAT1 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0055085| transmembrane transport TRPV2;SLC22A8;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;TRPA1;SLC22A6;CACNA1G;ABCC1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1H;TRPV3;SLC22A8;GLRA3;TRPV2;CHRNA7 GO:0098656| SLC22A8;VDAC1;SLC22A6 20308:[DB14011 DB08647] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08647|TRAZEOLIDE IGKC common genes common pathways GO:0045087| innate immune response IGKC;PPARG GO:0002376| immune system process IDO1;IGKC GO:0006955| immune response IGKC;CNR2;OPRD1 GO:0001895| retina homeostasis IGKC;SOD1 20309:[DB14011 DB02935] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02935|Diglyme HSP90B1 common genes common pathways GO:0034976| response to endoplasmic reticulum stress ALOX15;HSP90B1 GO:0071318| cellular response to ATP SOD1;PTGS2;HSP90B1;TRPV1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HSP90B1;PTGS2;HMGCR GO:0001666| response to hypoxia CYP1A1;HSP90B1;CAT;CHRNA7 20310:[DB14011 DB07050] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07050|5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide CA2 common genes common pathways GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CA2;PPARG;CYP1A1;TRPA1 GO:0001822| kidney development CA2;CAT GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 20311:[DB14011 DB03125] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP2C9;CYP1A1;CRYZ;DHFR;PTGS1;ALOX5;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 20312:[DB14011 DB02140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02140|N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide CTSH common genes common pathways GO:0006919| activation of caspase activity CTSH;PPARG GO:0032526| response to retinoic acid CTSH;PPARG GO:0008284| positive regulation of cell proliferation CTSH;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0043066| negative regulation of apoptotic process CTSH;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;CTSH GO:0006915| apoptotic process VDAC1;CTSH;GPX1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;CTSH GO:0010628| positive regulation of gene expression CTSH;TRPV4 20313:[DB14011 DB04714] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0006694| steroid biosynthetic process FDPS;HMGCR;CYP17A1 GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0008203| cholesterol metabolic process HMGCR;FDPS;CAT GO:0008299| isoprenoid biosynthetic process FDPS;HMGCR;GGPS1 GO:0045540| regulation of cholesterol biosynthetic process FDPS;HMGCR;GGPS1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;FDPS;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6 GO:0016032| viral reproduction VDAC1;FDPS;HTR2A GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;FDPS;NAAA;GPX1;PTGS1 GO:0016126| sterol biosynthetic process FDPS;HMGCR 20314:[DB14011 DB06979] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06979|5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid HAO1 common genes common pathways GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;HAO1;PTGS2;SOD1 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;HAO1;PTGS2;CYP3A7;CYP1A2;HMGCR 20315:[DB14011 DB09477] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways GO:0030308| negative regulation of cell growth BDKRB1;PPARG GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;BDKRB1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0009612| response to mechanical stimulus TRPV4;PPARG;BDKRB1 GO:0001822| kidney development CAT;ACE GO:0007283| spermatogenesis ACE;CNR1;SOD1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;BDKRB1;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0006954| inflammatory response BDKRB1;TRPV1;IDO1;ALOX15;CNR2;PTGS2;PTGS1;ALOX5 GO:0019233| sensory perception of pain OPRM1;CNR2;PTGS2;OPRD1;HTR2A;CNR1;TRPV1;BDKRB1;TRPA1 GO:0045776| negative regulation of blood pressure CNR1;BDKRB1 GO:0008217| regulation of blood pressure ACE;PTGS1;SOD1;PTGS2;PPARG GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;BDKRB1;TRPV4;TRPV1 GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0060047| heart contraction SOD1;ACE;GPX1 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;BDKRB1;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 20316:[DB14011 DB08402] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08402|2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID PPARG;NCOA2;RXRA common genes PPARG common pathways GO:0007623| circadian rhythm AANAT;NCOA2 GO:0008203| cholesterol metabolic process HMGCR;CAT;RXRA GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;PLA2G1B GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;NCOA2;RXRA;PPARG GO:0045087| innate immune response PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRA;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0030224| monocyte differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process PPARG;NCOA2;AANAT GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 GO:0031000| response to caffeine PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG GO:0048469| cell maturation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0007507| heart development PPARG;RXRA GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2 GO:0042953| lipoprotein transport PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0051289| protein homotetramerization TRPV1;TRPM8;CRYZ;TRPA1;RXRA;CAT GO:0016032| viral reproduction HTR2A;VDAC1;RXRA GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:1905461| PPARG GO:0007566| embryo implantation RXRA;PTGS2;SOD1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;NCOA2;CYP1A1;PPARG;RXRA GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0007165| signal transduction GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;RXRA;PPARG GO:0055088| lipid homeostasis PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 20317:[DB14011 DB08795] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport TRPV2;SLC15A2;ABCG2;TRPV1;CACNA1I;SLC15A1;ABCC1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;SLC15A1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;SLC15A2;SLC22A5;TRPV2 GO:0006811| ion transport TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;TRPM8;CACNA1G;SLC15A1;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;SLC15A2;SLC22A5 GO:0006855| drug transmembrane transport SLC22A5;ABCG2;ABCC1 20318:[DB14011 DB07340] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07340|N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine AURKB;INCENP common genes common pathways GO:0008283| cell proliferation GPX1;HTR1A;AURKB;CYP1A1 GO:0034644| cellular response to UV AURKB;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter AURKB;TRPV4;TRPV1;PPARG GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT;CYP1A1;AURKB 20319:[DB14011 DB13421] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13421|Edoxudine ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;ALB GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 20320:[DB14011 DB12023] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways GO:0008283| cell proliferation GPX1;HTR1A;IL5RA;CYP1A1 GO:0007165| signal transduction CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;IL5RA;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0065009| regulation of molecular function IL5RA;TRPV1 GO:0006955| immune response CNR2;OPRD1;FCGR3A 20321:[DB14011 DB05423] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05423|ORG-34517 NR3C1 common genes common pathways GO:0006915| apoptotic process VDAC1;GPX1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;NR3C1;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;CHRNA7 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 20322:[DB14011 DB06898] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06898|4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol ESR1;NCOA2 common genes common pathways GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0032870| cellular response to hormone stimulus NCOA2;CACNA1H GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;ESR1;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;HTR2A;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NCOA2;PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV4;TRPV1;NCOA2;PPARG GO:0007623| circadian rhythm AANAT;NCOA2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TRPV1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0048511| rhythmic process NCOA2;PPARG;AANAT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NCOA2 20323:[DB14011 DB04477] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04477|N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0045821| positive regulation of glycolysis GAPDHS;HTR2A GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;GAPDHS;CRYZ;CYP1A1;CYP2C9 GO:0030317| sperm motility CACNA1I;GAPDHS 20324:[DB14011 DB05415] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05415|OSI-461 PDE5A common genes common pathways GO:0043406| positive regulation of MAP kinase activity PDE5A;HTR2A GO:0042130| negative regulation of T cell proliferation PDE5A;IDO1 GO:0008152| metabolic process ACAT1;SMPD1;PDE5A GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;PDE5A;SMPD1;PPARG;GPR18 20325:[DB14011 DB04618] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04618|4,6-DIDEOXY-4-{[4-[(4-O-HEXOPYRANOSYLHEXOPYRANOSYL)OXY]-5,6-DIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}HEXOPYRANOSYL-(1->4)HEXOPYRANOSYL-(1->4)HEXOPYRANOSE AMY2A common genes common pathways GO:0008152| metabolic process SMPD1;AMY2A;ACAT1 20326:[DB14011 DB00431] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00431|Lindane GABRB1;GLRA1;GLRA2;GLRA3;GLRB;GABRB3;GABRR1;PGR;ESR1;NR1I2 common genes GLRA3;GLRA1;GLRB common pathways GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0008202| steroid metabolic process CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A1;CYP2C9;NR1I2;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0097112| gamma-aminobutyric acid receptor clustering GLRB GO:0006810| transport GABRR1;GABRB1;GABRB3;TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;ESR1 GO:0006936| muscle contraction CACNA1H;GLRA1 GO:0042391| regulation of membrane potential CACNA1H;GLRB;CACNA1G;GLRA1 GO:0006820| anion transport VDAC1;GLRA1 GO:0007605| sensory perception of sound GABRB3;GPX1;SOD1 GO:0034220| ion transmembrane transport GABRB1;GABRR1;GLRA3;GLRA2;GABRB3;CHRNA7;TRPA1;GLRA1;TRPV1;GLRB GO:0043200| response to amino acid stimulus GLRA3;GLRB GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0010628| positive regulation of gene expression TRPV4;NR1I2 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG GO:0060080| regulation of inhibitory postsynaptic membrane potential GABRB3;GLRA1 GO:0001508| regulation of action potential GLRA1;CACNA1G GO:0043523| regulation of neuron apoptosis GPX1;GABRB3 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0071230| cellular response to amino acid stimulus GLRA2;GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;GLRA2;SLC29A1;GLRA1;TRPV1;GLRB GO:0007340| acrosome reaction GLRA1;GLRB GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;GLRA2;GLRA1;GLRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;PGR;NR1I2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;TRPV4;TRPV1 GO:0007628| adult walking behavior GLRB;GLRA1 GO:0050905| neuromuscular process GLRB;GLRA1 GO:0006355| regulation of transcription, DNA-dependent PGR;PPARG;NR1I2;ESR1 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG;ESR1 GO:0050884| neuromuscular process controlling posture GLRA1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG;NR1I2;PGR GO:0060012| synaptic transmission, glycinergic GLRB;GLRA1;GLRA2;GLRA3 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1 GO:0042908| xenobiotic transport ABCG2;ABCC1;NR1I2 GO:0006821| chloride transport GLRA1;GLRB;GLRA3;GABRR1;GABRB1;GLRA2;GABRB3 GO:2000344| positive regulation of acrosome reaction GLRA1;CACNA1H GO:0007165| signal transduction PGR;PLA2G1B;CACNA1I;SMPD1;PPARG;NR1I2;GPR18;GABRB3;CHRNA7;OPRM1;CNR2;OPRD1;GABRB1;GPR55;HTR1A;ESR1;CNR1;GPR12;HTR2A GO:0006811| ion transport TRPV2;CHRNA7;GABRB3;GLRA2;TRPV3;GABRB1;CACNA1H;GLRA3;GABRR1;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;GABRB1 GO:0051291| protein heterooligomerization GLRB;GLRA1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0071294| cellular response to zinc ion GLRA1;GLRA2 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;PGR;ESR1 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;PGR;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;NR1I2;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0007399| nervous system development SMPD1;GLRB GO:0071361| cellular response to ethanol GLRA2;GLRA1 GO:0097305| GLRA1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;NR1I2;CYP2C9 GO:0010629| negative regulation of gene expression OPRD1;ESR1;PGR GO:0007268| synaptic transmission GLRA2;GLRA3;HTR2A;GABRR1;OPRD1;OPRM1;GLRB;VDAC1;GLRA1;CACNA1G GO:0043524| negative regulation of neuron apoptosis SOD1;GABRB3 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0001964| startle response GLRB;GLRA1 GO:0060013| righting reflex GLRA1;GLRB GO:1902476| GLRA1;GLRB;GABRB1;GLRA3;GABRR1;GABRB3;GLRA2 20327:[DB14011 DB06896] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways GO:0008283| cell proliferation CYP1A1;MET;HTR1A;GPX1 GO:0007165| signal transduction CNR2;OPRM1;MET;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway MET;TRPV1;TRPA1 GO:0051897| positive regulation of protein kinase B signaling cascade MET;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PLA2G1B;PPARG 20328:[DB14011 DB03981] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways GO:0008284| positive regulation of cell proliferation FGF2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;FGF2 GO:0002576| platelet degranulation SOD1;ANXA5 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;ANXA5;HMGCR;PTGS2 GO:0042060| wound healing OPRM1;FGF2;ALOX15 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGF2 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;PPARG GO:0051209| release of sequestered calcium ion into cytosol HTR2A;FGF2;TRPV1;TRPA1 GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;ANXA5;SOD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;FGF2;HMGCR;GPR55;HTR2A GO:0045766| positive regulation of angiogenesis CHRNA7;FGF2;CYP1B1 GO:0000187| activation of MAPK activity PLA2G1B;FGF2;SOD1;CHRNA7 GO:0007399| nervous system development FGF2;GLRB;SMPD1 GO:0061045| negative regulation of wound healing HMGCR;FGF2 GO:0001525| angiogenesis CYP1B1;FGF2;PTGS2 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;ANXA5;HTR1A;GPR55;GPR12;CNR1;HTR2A;FGF2;CNR2;OPRM1;OPRD1;CHRNA7 GO:0051781| positive regulation of cell division CAT;FGF2 GO:0043537| negative regulation of blood vessel endothelial cell migration FGF2;PPARG 20329:[DB14011 DB07968] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways GO:0043312| neutrophil degranulation CAT;ALOX5;PYGL GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;PYGL GO:0008152| metabolic process ACAT1;PYGL;SMPD1 20330:[DB14011 DB03987] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;DHFR;CRYZ;CYP1A1;CYP2C9 20331:[DB14011 DB04076] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04076|Hypoxanthine PNP;CYP1A2 common genes CYP1A2 common pathways GO:0006955| immune response CNR2;OPRD1;PNP GO:0006195| purine nucleotide catabolic process GPX1;PNP GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;PNP GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;ACAT1;AANAT GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP1A2;CYP3A4 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;GPX1;PTGS1 GO:0042493| response to drug ABCC1;SMPD1;PPARG;PNP;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0043312| neutrophil degranulation ALOX5;CAT;PNP GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0010468| regulation of gene expression CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 20332:[DB14011 DB07403] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways GO:0008631| induction of apoptosis by oxidative stress PDK1;CYP1B1;GPX1 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1;PDK1 20333:[DB14011 DB05971] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05971|Archexin AKT1 common genes common pathways GO:0008283| cell proliferation AKT1;HTR1A;GPX1;CYP1A1 GO:0006809| nitric oxide biosynthetic process CYP1B1;AKT1 GO:0071380| cellular response to prostaglandin E stimulus PPARG;AKT1 GO:0045600| positive regulation of fat cell differentiation AKT1;HTR2A;PPARG GO:0071276| cellular response to cadmium ion AKT1;CYP1A2;SOD1 GO:0031999| negative regulation of fatty acid beta-oxidation CNR1;AKT1 GO:0032287| peripheral nervous system myelin maintenance SOD1;AKT1 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;AKT1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;AKT1 GO:0001649| osteoblast differentiation CAT;AKT1 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;AKT1 GO:0045907| positive regulation of vasoconstriction HTR2A;AKT1;PTGS2 GO:0009725| response to hormone stimulus AKT1;ACAT1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;AKT1;OPRD1 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;AKT1;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0010629| negative regulation of gene expression OPRD1;AKT1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;AKT1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;AKT1;GPX1 GO:0006954| inflammatory response AKT1;PTGS2;CNR2;ALOX5;PTGS1;TRPV1;IDO1;ALOX15 GO:0009408| response to heat TRPV1;TRPV3;AKT1;SOD1;TRPV2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;AKT1 GO:0000060| protein import into nucleus, translocation AKT1;OPRD1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;AKT1;PTGS2;SOD1;CNR1 GO:0035556| intracellular signal transduction AKT1;PLA2G1B GO:0007399| nervous system development SMPD1;GLRB;AKT1 GO:1990090| TRPV1;AKT1 GO:0071260| cellular response to mechanical stimulus PTGS2;AKT1 GO:0006915| apoptotic process GPX1;AKT1;VDAC1 GO:0071356| cellular response to tumor necrosis factor AKT1;TRPV1 GO:0015758| glucose transport PLA2G1B;AKT1 GO:0010033| response to organic substance CYP1A2;PTGS2;AKT1;SOD1;CYP1A1;PPARG;TRPA1 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;AKT1;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;AKT1;OPRD1;PPARG;GPR18 GO:0071456| cellular response to hypoxia OPRD1;AKT1;PTGS2;SLC29A1 GO:0007568| aging CYP1A1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;AKT1;PTGS2 GO:0042593| glucose homeostasis AKT1;CNR1;PPARG;TRPV4 GO:0006979| response to oxidative stress SOD1;PTGS2;AKT1;CAT;GPX1;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;AKT1;TRPV1 GO:0045893| positive regulation of transcription, DNA-dependent AKT1;PPARG GO:0032094| response to food CYP1A1;AKT1;OPRM1 GO:0071407| cellular response to organic cyclic compound AKT1;CYP1A1;CYP1B1 GO:1902176| GPX1;AKT1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;AKT1;PTGS2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;AKT1;CHRNA7;SLC29A1;GLRA1;GLRB;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AKT1;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;AKT1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;AKT1;HMGCR;PTGS2;SOD1 20334:[DB14011 DB02996] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02996|2-(Thiomethylene)-4-Methylpentanoic Acid ADAM28 common genes common pathways GO:0007283| spermatogenesis ADAM28;CNR1;SOD1 20335:[DB14011 DB06240] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06240|Tariquidar ABCB1 common genes common pathways GO:0055085| transmembrane transport TRPV4;ABCB1;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0006810| transport ABCC1;ABCG2;TRPV1;CACNA1I;ABCB1;TRPV2 GO:0042493| response to drug ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 20336:[DB14011 DB07665] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07665|N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide F2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0061844| F2;PLA2G1B 20337:[DB14011 DB03821] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03821|2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid ARSA;ARSA common genes common pathways GO:0008152| metabolic process SMPD1;ARSA;ACAT1 GO:0006687| glycosphingolipid metabolic process SMPD1;ARSA GO:0043312| neutrophil degranulation ARSA;CAT;ALOX5 20338:[DB14011 DB00806] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes CYP1A2 common pathways GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0010468| regulation of gene expression CYP1A2 GO:0097756| ADORA1;HMGCR;PTGS2 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway ADORA1;PPARG;ADORA2A;GPR18;PDE4B;CNR2;OPRM1;PDE4A;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0031000| response to caffeine ADORA2A;PPARG GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;ADORA2A GO:0042130| negative regulation of T cell proliferation IDO1;PDE5A GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0043406| positive regulation of MAP kinase activity PDE5A;HTR2A GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0001666| response to hypoxia CYP1A1;ADORA1;CAT;CHRNA7 GO:0006915| apoptotic process GPX1;ADORA2A;VDAC1 GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1;ADORA1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0016042| lipid catabolic process NAPEPLD;ADORA1;DAGLA;PLA2G1B GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0035307| positive regulation of protein dephosphorylation SMPD1;ADORA1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0043066| negative regulation of apoptotic process ADORA1;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0042311| vasodilation GPX1;ADORA2A GO:0007626| locomotory behavior OPRM1;SOD1;ADORA2A GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1;ADORA2A;ADORA1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;ADORA1 GO:0050728| negative regulation of inflammatory response CNR2;NT5E;ADORA2A;ADORA1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent PPARG;ADORA2A GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;ADORA2A;TRPA1;PPARG;CYP1A1;ABCG2 GO:0097267| CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 GO:0007165| signal transduction PDE5A;SMPD1;ADORA1;PPARG;ADORA2A;GPR18;CACNA1I;PLA2G1B;PDE4B;CNR2;OPRM1;OPRD1;PDE4A;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADORA1 GO:0001975| response to amphetamine ADORA2A;SOD1;CNR2 GO:0050890| cognition CHRNA7;ADORA1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;ADORA1;PPARG;ADORA2A;CYP1B1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0045777| positive regulation of blood pressure ADORA1;CNR1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1;ADORA2A GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0032229| negative regulation of synaptic transmission, GABAergic ADORA1;CNR2 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADORA1 GO:0045333| cellular respiration CYP1A2 GO:0042755| eating behavior OPRM1;OPRD1;ADORA2A GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1 GO:0007399| nervous system development GLRB;SMPD1;ADORA1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0008152| metabolic process SMPD1;PDE5A;ACAT1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADORA2A;CNR1 GO:0001659| temperature homeostasis ADORA1;TRPV1;HTR2A;GPX1 GO:0045776| negative regulation of blood pressure CNR1;ADORA1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0007600| sensory perception OPRM1;TRPV2;ADORA2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1;ADORA1 GO:0051924| regulation of calcium ion transport ADORA2A;OPRD1 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;ADORA1;ADORA2A;TRPV1;ALOX15;IDO1 GO:0006195| purine nucleotide catabolic process GPX1;NT5E GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2;GPX1 GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 20339:[DB14011 DB08303] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08303|(3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide GRIA2 common genes common pathways GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;GRIA2;CHRNA7;GLRA3 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;GRIA2;CHRNA7;GLRA1;TRPV1;GLRB GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;GRIA2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB GO:0007165| signal transduction GRIA2;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;GLRA3;HTR2A;OPRD1;OPRM1;GRIA2 20340:[DB14011 DB07999] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07999|{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance TRPA1;AKR1B1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2;HMGCR GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;AKR1B1;CYP1A1;CYP2C9;CRYZ GO:0022900| electron transport chain CYP1A2;AKR1B1;GSR;IDO1 20341:[DB14011 DB04470] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04470|CRA_10656 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20342:[DB14011 DB01273] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes CHRNA7 common pathways GO:0050808| synapse organization CHRNA7 GO:0035640| exploration behavior CHRNA4;HTR1A GO:0050893| sensory processing CHRNA7 GO:0035094| response to nicotine CHRNA6;CNR1;CHRNA4;CHRNA7;CHRNB2 GO:0051247| positive regulation of protein metabolic process CHRNA7 GO:0007612| learning PTGS2;VDAC1;CHRNB2 GO:0001508| regulation of action potential CHRNA4;CHRNB2;CACNA1G;GLRA1 GO:0007611| learning or memory CHRNA7;CNR1 GO:1905144| CHRNA7;CHRNA3;CHRNB2 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;CHRNA4;GLRA3;CHRNA6;OPRM1;CHRNA3;GLRB;TRPV1;GLRA1;CHRNB2 GO:0007614| short-term memory CHRNA7 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:1905906| CHRNA7 GO:0007626| locomotory behavior CHRNB2;CHRNA3;SOD1;OPRM1;CHRNA4 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0095500| CHRNB2;CHRNA3;CHRNA4;CHRNA7 GO:0034220| ion transmembrane transport GLRB;CHRNA3;TRPV1;CHRNB2;TRPA1;GLRA1;CHRNA4;CHRNA7;GLRA3;CHRNA6 GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;SLC22A2;TRPV1;CACNA1I;TRPV4;VDAC1;TRPA1;CACNA1G;ABCC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:1905920| CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B GO:0042220| response to cocaine SMPD1;CHRNB2;CNR1;OPRM1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0140059| CHRNA7 GO:0001666| response to hypoxia CYP1A1;CHRNB2;CAT;CHRNA7;CHRNA4 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7 GO:1902991| CHRNA7 GO:0014059| regulation of dopamine secretion CHRNB2;HTR2A;CHRNA6;CHRNA4 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1;CHRNA4 GO:0098815| CHRNA7 GO:0045759| negative regulation of action potential CNR1;CNR2;CHRNB2 GO:0006810| transport TRPV2;CHRNA6;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;CHRNA7 GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;TRPV4;TRPM8 GO:1901214| CHRNA7 GO:0006979| response to oxidative stress CHRNA4;GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0042391| regulation of membrane potential CACNA1H;CHRNA4;GLRA1;CACNA1G;CHRNB2;GLRB;CHRNA3 GO:0007605| sensory perception of sound CHRNB2;GPX1;SOD1 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;CHRNA4;HTR2A;GLRA3;CHRNA6;OPRD1;OPRM1 GO:1902004| CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7 GO:1902430| CHRNA7 GO:0006816| calcium ion transport TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;CHRNB2;CHRNA7;CHRNA4;TRPV2;TRPV3;CACNA1H GO:0008542| visual learning HMGCR;CHRNB2 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;CHRNB2 GO:0019233| sensory perception of pain CHRNA4;OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A;TRPV1;CHRNB2;TRPA1 GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0007399| nervous system development SMPD1;GLRB;CHRNA3 GO:0060078| regulation of postsynaptic membrane potential CHRNA6;CHRNA7;CHRNB2 GO:0006811| ion transport CHRNA6;GLRA3;CACNA1H;TRPV3;CHRNA7;CHRNA4;TRPV2;TRPA1;GLRA1;CACNA1G;CHRNB2;SLC22A2;TRPM8;VDAC1;GLRB;CHRNA3;TRPV4;CACNA1I;TRPV1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A2 GO:0042053| regulation of dopamine metabolic process HTR1A;CHRNB2 GO:0051291| protein heterooligomerization GLRB;GLRA1;CHRNB2 GO:0006812| cation transport SLC22A2;TRPM8 GO:0050890| cognition CHRNA4;CHRNA7;CHRNB2 GO:0097061| dendritic spine organization CHRNA7 GO:0007613| memory CHRNB2;CHRNA7;HTR2A;CNR1;PTGS2 GO:0007601| visual perception CRYZ;GLRA1;CHRNB2;CYP1B1;GLRB GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;CACNA1H;OPRM1;TRPV3;TRPM8;TRPV1;CACNA1I;TRPV4;TRPA1;CACNA1G GO:0006939| smooth muscle contraction CHRNB2;HTR2A GO:1900273| CHRNA7 GO:1904645| CHRNA7 GO:0007165| signal transduction CACNA1I;CHRNA3;PLA2G1B;PPARG;GPR18;CHRNB2;SMPD1;CHRNA7;CHRNA4;HTR1A;CHRNA6;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 20343:[DB14011 DB08856] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08856|DADLE SLCO1B1 common genes common pathways GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;SLCO1B1;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0006811| ion transport CACNA1H;TRPV3;SLCO1B1;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8 20344:[DB14011 DB07447] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0016042| lipid catabolic process PLA2G1B;DAGLA;AKR1D1;NAPEPLD GO:0008202| steroid metabolic process CYP3A7;AKR1D1;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;AKR1D1;PTGS2;CYP3A7;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP1A1;CYP2C9;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1 GO:0008209| androgen metabolic process CYP3A4;AKR1D1 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;AKR1D1;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B 20345:[DB14011 DB08729] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways GO:0042130| negative regulation of T cell proliferation PDE5A;IDO1 GO:0043406| positive regulation of MAP kinase activity HTR2A;PDE5A GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;PDE5A;CACNA1I;PLA2G1B GO:0008152| metabolic process PDE5A;SMPD1;ACAT1 20346:[DB14011 DB09037] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09037|Pembrolizumab PDCD1 common genes common pathways GO:0006915| apoptotic process GPX1;PDCD1;VDAC1 GO:0002376| immune system process IDO1;PDCD1 GO:0070234| positive regulation of T cell apoptosis IDO1;PDCD1 GO:0043066| negative regulation of apoptotic process PTGS2;PDCD1;HMGCR;SOD1;GPX1;CAT GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;PDCD1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PDCD1;PTGS2;SOD1;CNR1 20347:[DB14011 DB00498] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00498|Phenindione VKORC1 common genes common pathways GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;VKORC1;PTGS2;CYP3A7;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP3A4;VKORC1;CYP1A2;CYP1A1;CYP2C9;CYP2D6;CYP2C19 20348:[DB14011 DB03194] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03194|beta-L-methyl-fucose MBL2 common genes common pathways GO:0002376| immune system process MBL2;IDO1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;MBL2 GO:0050830| defense response to Gram-positive bacterium MBL2;PLA2G1B GO:0045087| innate immune response MBL2;PPARG 20349:[DB14011 DB08878] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0006879| cellular iron ion homeostasis SLC46A1;SOD1;ABCG2 GO:0055114| oxidation-reduction process CRYZ;DHFR;CYP2C9;CYP1A1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;GPX1;ALOX5;PTGS1 GO:0015886| heme transport ABCG2;SLC46A1 GO:0055085| transmembrane transport ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1;SLC46A1;TRPV2;CACNA1H;TRPV3 20350:[DB14011 DB14146] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes OPRM1;OPRD1 common pathways GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0009314| response to radiation PTGS2;OPRM1;CAT;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRK1;OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A GO:0045471| response to ethanol OPRK1;CAT;HMGCR;OPRM1;SOD1;CNR1 GO:0000060| protein import into nucleus, translocation OPRD1 GO:0006955| immune response OPRD1;CNR2;OPRK1 GO:0007600| sensory perception TRPV2;OPRM1;OPRK1 GO:0051924| regulation of calcium ion transport OPRD1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission GLRA1;CACNA1G;OPRK1;VDAC1;GLRB;HTR2A;GLRA3;OPRD1;OPRM1 GO:0010629| negative regulation of gene expression OPRD1 GO:0070588| calcium ion transmembrane transport CACNA1H;OPRM1;TRPV3;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;TRPM8 GO:0044849| OPRM1;OPRK1 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRK1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A GO:0071315| cellular response to morphine OPRM1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0042755| eating behavior OPRM1;OPRD1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRM1;OPRD1 GO:0008344| adult locomotory behavior OPRD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0032868| response to insulin stimulus CAT;AANAT;OPRK1;TRPV4 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007218| neuropeptide signaling pathway OPRK1;GLRB;GLRA1;GLRA3;OPRD1;OPRM1 GO:0007626| locomotory behavior OPRM1;SOD1;OPRK1 GO:0070848| response to growth factor stimulus OPRM1 GO:0033554| cellular response to stress OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;CYP1A1;IDO1 GO:0042060| wound healing ALOX15;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;TRPV1;GLRB GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;OPRK1 GO:0043278| response to morphine OPRK1;OPRM1;CNR1 GO:0032100| positive regulation of appetite OPRM1 GO:0097237| OPRD1 GO:0032094| response to food OPRM1;CYP1A1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCB1;ABCG2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0032793| positive regulation of CREB transcription factor activity OPRD1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRK1;PPARG;GPR18 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0006810| transport TRPV1;ABCB1;CACNA1I;ABCG2;ABCC1;TRPV2 GO:0038003| opioid receptor signaling pathway OPRK1;OPRM1;OPRD1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0032460| negative regulation of protein oligomerization OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;OPRK1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 20351:[DB14011 DB14029] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14029|Furafylline CYP1A2 common genes CYP1A2 common pathways GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0010468| regulation of gene expression CYP1A2 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6 20352:[DB14011 DB09107] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways GO:0046697| decidualization PTGS2;EPOR GO:0007420| brain development ACAT1;EPOR GO:0007165| signal transduction EPOR;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0007507| heart development EPOR;PPARG 20353:[DB14011 DB03005] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development ACHE;CACNA1H GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0008283| cell proliferation CYP1A1;GPX1;ACHE;HTR1A 20354:[DB14011 DB00159] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes TRPV1;PPARG;PTGS1;PTGS2 common pathways GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0071468| cellular response to acidity TRPV1 GO:0051209| release of sequestered calcium ion into cytosol TRPV1;TRPA1;HTR2A GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:1902219| PTGS2 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;FFAR1;PPARG;GPR18 GO:0007635| chemosensory behavior TRPV1 GO:0007568| aging CYP1A1;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;CAT GO:0015909| long-chain fatty acid transport PPARG GO:0030282| bone mineralization PTGS2;ALOX15 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PPARD GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;TRPV2 GO:0046697| decidualization PPARD;PTGS2 GO:0071456| cellular response to hypoxia PPARD;OPRD1;PTGS2;SLC29A1;SLC8A1 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0097756| PTGS2;HMGCR GO:0043388| positive regulation of DNA binding PPARG GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0006874| cellular calcium ion homeostasis SLC8A1;CHRNA7;GPR12;HTR2A;TRPV4;TRPM8 GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0006936| muscle contraction GLRA1;CACNA1H;SLC8A1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG;FFAR1 GO:0031100| organ regeneration PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0034220| ion transmembrane transport TRPV1;GLRB;GLRA1;TRPA1;CHRNA7;GLRA3 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0071502| cellular response to temperature stimulus TRPV1 GO:0006915| apoptotic process GPX1;PPARD;VDAC1 GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG;PPARA GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;CACNA1H;TRPV3;TRPV2;SLC8A1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;SLC8A1;PPARA GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0010033| response to organic substance CYP1A2;PTGS2;PPARD;SOD1;CYP1A1;PPARG;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031000| response to caffeine PPARG GO:0015758| glucose transport PPARD;PLA2G1B GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0008203| cholesterol metabolic process CAT;PPARD;HMGCR GO:0007612| learning VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PPARD;PTGS2;PTGS1 GO:0042060| wound healing ALOX15;PPARA;OPRM1;PPARD GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0070509| calcium ion import CACNA1I;TRPV4;CACNA1G;SLC8A1;CACNA1H GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;SLC8A1 GO:0071284| cellular response to lead ion PTGS2 GO:0001660| fever generation TRPV1 GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0002024| diet induced thermogenesis TRPV4;TRPV1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;GLRA1;GLRB;TRPV1 GO:0032526| response to retinoic acid PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PPARD;HMGCR;PTGS2;ALB GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0002576| platelet degranulation ALB;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;PPARD;HMGCR GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A2;SLC8A1;PPARG;CYP1A1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PPARD;PPARA GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PPARA;PTGS2;PTGS1;FADS1;ACSL3;ALOX15;ACSL4 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARD;PPARA GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;SLC8A1;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARD;PPARG;FADS1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;FADS1;CYP2C9;CYP1A1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0030224| monocyte differentiation PPARG GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPV1;TRPA1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0050728| negative regulation of inflammatory response PPARD;CNR2;PPARA GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0071455| cellular response to hyperoxia PPARG GO:0048265| response to pain TRPA1;TRPV1 GO:0033189| response to vitamin A CYP1A1;PPARG;CAT;PPARD GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0016525| negative regulation of angiogenesis PPARG GO:0009750| response to fructose stimulus PTGS2 GO:0009062| fatty acid catabolic process FAAH;PPARD GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD;PPARA GO:0019216| regulation of lipid metabolic process HMGCR;PPARA;CNR1;CYP1A1;PPARG;FADS1 GO:0007566| embryo implantation SOD1;PPARD;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:1905461| PPARG GO:0022008| neurogenesis FABP7;DAGLA GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0007204| elevation of cytosolic calcium ion concentration SLC8A1;HTR2A;OPRM1;TRPV1;TRPV4 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2;SLC8A1;TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I GO:0006641| triglyceride metabolic process ACSL4;GPX1;CAT GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid FFAR1;PTGS2;CAT GO:0065009| regulation of molecular function FFAR1;TRPV1 GO:0007165| signal transduction FFAR1;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PLA2G1B;FADS1;ACSL3;PTGS1;PTGS2 GO:0007420| brain development ACAT1;ACSL3 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACSL3;ACAT1;AANAT;PTGS2;CYP1A2 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;GLRA3;CACNA1H;TRPV3;CHRNA7;SLC8A1;TRPV2 GO:0033280| response to vitamin D PTGS2 GO:0008283| cell proliferation GPX1;PPARD;HTR1A;CYP1A1 GO:0001895| retina homeostasis ALB;SOD1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0032868| response to insulin stimulus TRPV4;PPARA;AANAT;CAT GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARD;SOD1;PPARG GO:0060612| adipose tissue development PPARD;ACAT1 GO:0019395| fatty acid oxidation PPARG;PPARD GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;PPARD GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;FABP7;PTGS2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0014823| response to activity PPARD;CAT GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient ACSL4;ACSL3;PPARG;SLC8A1;HMGCR;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0048266| behavioral response to pain TRPV1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0001774| microglial cell activation TRPV1 GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARD;PPARG GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SLC8A1;CACNA1H GO:0019233| sensory perception of pain CNR1;HTR2A;PTGS2;CNR2;OPRM1;OPRD1;TRPA1;TRPV1 GO:0006351| transcription, DNA-dependent PPARG;PPARD;PPARA GO:1901594| TRPV1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0048469| cell maturation PPARG GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:1990776| PTGS2 GO:0008152| metabolic process ACSL4;SMPD1;ACSL3;ACAT1 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0071312| cellular response to alkaloid TRPV1 GO:0050727| regulation of inflammatory response PTGS2 GO:0001659| temperature homeostasis GPX1;HTR2A;TRPV1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0050955| thermoception TRPV1;TRPM8;TRPA1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;SLC8A1;GPX1;CAT GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;ACSL4;CYP2D6;DAGLA;ACSL3;CYP2C9;PPARG;FADS1;NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;PPARD;PPARA;NAPEPLD;CYP3A4 GO:0051974| negative regulation of telomerase activity PPARG GO:0060078| regulation of postsynaptic membrane potential CHRNA7;SLC8A1 GO:0042953| lipoprotein transport PPARG GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0007507| heart development PPARG;PPARA;PPARD GO:1990090| TRPV1 GO:0045165| cell fate commitment PPARG GO:0007399| nervous system development GLRB;SMPD1;FABP7 GO:0002027| regulation of heart rate SLC8A1;CACNA1G GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071320| cellular response to cAMP SLC8A1;AANAT GO:0098703| TRPV1 GO:0061614| PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0001964| startle response FABP7;GLRA1;GLRB GO:0006816| calcium ion transport TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;TRPA1;TRPV2;SLC8A1;CHRNA7;TRPV3;CACNA1H GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:0051289| protein homotetramerization TRPM8;TRPV1;TRPA1;CRYZ;CAT GO:0009408| response to heat TRPV3;SOD1;TRPV2;TRPV1 GO:0014047| glutamate secretion TRPV1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ALOX5;PTGS1;PTGS2;CNR2 GO:0010942| positive regulation of cell death PTGS2 GO:0009268| response to pH TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0002790| peptide secretion TRPV1 GO:0050872| white fat cell differentiation PPARG GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0051924| regulation of calcium ion transport SLC8A1;OPRD1 20355:[DB14011 DB08442] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08442|4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol HSP90AA1 common genes common pathways GO:0009409| response to cold TRPM8;TRPA1;HSP90AA1;PPARG GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;SOD1;TRPV3 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;HSP90AA1;GPR18 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;OPRM1;PTGS2 20356:[DB14011 DB04273] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04273|8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 20357:[DB14011 DB02831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02831|Dihydrogenphosphate DCXR common genes common pathways GO:0051289| protein homotetramerization TRPV1;TRPM8;TRPA1;CRYZ;DCXR;CAT GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;DCXR;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 20358:[DB14011 DB00649] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0006139| nucleobase-containing compound metabolic process SLC29A1;SLC28A1 GO:0098656| SLC22A6;VDAC1 GO:0015858| nucleoside transport SLC29A1;SLC28A1 GO:1901642| SLC28A1;SLC29A1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR;ALB GO:0055085| transmembrane transport ABCC1;SLC22A6;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ALB 20359:[DB14011 DB07495] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07495|5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AA1;TRPV1 GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;SOD1;TRPV3 GO:0009409| response to cold PPARG;HSP90AA1;TRPA1;TRPM8 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;HSP90AA1;PPARG;SMPD1;CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 20360:[DB14011 DB13200] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13200|Lipegfilgrastim CSF3R common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;CSF3R;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0007155| cell adhesion CSF3R;CYP1B1 GO:0030593| neutrophil chemotaxis PLA2G1B;CSF3R 20361:[DB14011 DB07406] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;MAPKAPK2;TRPV1;IDO1;ALOX15 GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;CYP1A1;MAPKAPK2;IDO1 GO:0034097| response to cytokine stimulus AANAT;PTGS2;MAPKAPK2 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15;MAPKAPK2 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;MAPKAPK2 20362:[DB14011 DB01643] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01643|Thymidine monophosphate tmk;DTYMK;dnaQ;TYMS;thyA;topA common genes common pathways GO:0043627| response to estrogen stimulus PPARG;DTYMK GO:0015949| nucleobase-containing small molecule interconversion TYMS;DTYMK;GSR GO:0008283| cell proliferation DTYMK;CYP1A1;GPX1;HTR1A GO:0009636| response to toxin CYP1A1;TYMS;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;PPARG;CYP1A1;TYMS;TRPA1 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0045445| myoblast differentiation DTYMK;HMGCR GO:0045471| response to ethanol TYMS;SOD1;CNR1;OPRM1;HMGCR;CAT GO:0046686| response to cadmium ion DTYMK;CAT GO:0007568| aging TYMS;CYP1A1;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT GO:0071363| cellular response to growth factor stimulus TRPV1;DTYMK;CAT;OPRD1 GO:0033189| response to vitamin A PPARG;TYMS;CYP1A1;CAT GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;ABCC1;TRPA1;CYP1A1;TYMS;PPARG;ABCG2 GO:0034097| response to cytokine stimulus TYMS;PTGS2;AANAT GO:0032259| methylation TYMS;CYP1A2 GO:0007623| circadian rhythm TYMS;AANAT 20363:[DB14011 DB00727] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0030308| negative regulation of cell growth NPR1;PPARG GO:0016525| negative regulation of angiogenesis NPR1;PPARG GO:0022900| electron transport chain ALDH2;CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP3A7;ALDH2;PTGS2;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway NPR1;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;GPR18;PPARG GO:0035556| intracellular signal transduction PLA2G1B;NPR1 GO:0008152| metabolic process SMPD1;ALDH2;ACAT1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;NPR1 GO:0048662| negative regulation of smooth muscle cell proliferation NPR1;PPARG GO:0008217| regulation of blood pressure PPARG;NPR1;PTGS1;PTGS2;SOD1 20364:[DB14011 DB00785] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007165| signal transduction SMPD1;CHRM3;PPARG;GPR18;PLA2G1B;CACNA1I;CHRM4;CHRM5;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CHRM1;CNR1;GPR12;HTR2A;CHRM2;CHRNA7 GO:0006939| smooth muscle contraction CHRM3;HTR2A GO:0050890| cognition CHRNA7;CHRM1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008283| cell proliferation CHRM4;CYP1A1;CHRM3;GPX1;HTR1A;CHRM1;CHRM5 GO:0007399| nervous system development CHRM3;SMPD1;GLRB;CHRM2;CHRM1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CHRM2;CNR1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;CHRM4 GO:0008016| regulation of heart contraction CACNA1H;CHRM2 GO:0019226| transmission of nerve impulse CHRM5;SOD1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;CHRM1;HTR2A;CNR1;GPR12;CHRM2;OPRM1;CHRM5;CNR2;OPRD1;CHRM4;PPARG;GPR18;CHRM3 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CHRM2;CNR1;OPRD1;CNR2;OPRM1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRM1;CHRNA7 GO:0009615| response to virus CHRM2;CYP1A1 20365:[DB14011 DB08061] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08061|4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE F2 common genes common pathways GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;GPR18;PPARG;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;F2 GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 20366:[DB14011 DB05197] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05197|Sofalcone CBR1 common genes common pathways GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2;CBR1 GO:0030855| epithelial cell differentiation VDAC1;PPARG;CBR1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CBR1;CAT;ALOX5;GPX1;PTGS1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1;CBR1 20367:[DB14011 DB07369] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;MET GO:0008283| cell proliferation HTR1A;MET;GPX1;CYP1A1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;MET;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;MET 20368:[DB14011 DB12742] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;KIT GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;MET GO:0035556| intracellular signal transduction PLA2G1B;KIT GO:0071312| cellular response to alkaloid TRPV1;RAD51 GO:0009314| response to radiation OPRM1;PTGS2;KIT;CAT GO:0007399| nervous system development GLRB;SMPD1;RET GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;PPARG GO:0016032| viral reproduction HTR2A;VDAC1;PDGFRA GO:0010976| positive regulation of neuron projection development RET;CNR1 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;KIT;TRPV1;ALOX15;IDO1 GO:0030217| T cell differentiation GPR18;KIT GO:0008542| visual learning KIT;HMGCR GO:0048565| digestive tract development CYP1A1;KIT GO:0071345| cellular response to cytokine stimulus FLT3;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;PDGFRA;TRPV1;TRPV4 GO:0065009| regulation of molecular function RET;TRPV1 GO:0007165| signal transduction HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;MET;OPRD1;CHRNA7;RET;KIT;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0006919| activation of caspase activity PPARG;RET GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;RAD51;CAT GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;RAD51;TRPA1;CYP1A1;PPARG GO:0008283| cell proliferation CYP1A1;GPX1;MET;HTR1A GO:0045740| positive regulation of DNA replication PDGFRA;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;PDGFRA GO:0042127| regulation of cell proliferation PTGS2;PTGS1;KIT GO:0042060| wound healing ALOX15;PDGFRA;OPRM1 GO:0071300| cellular response to retinoic acid PPARG;RET GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MET GO:0008284| positive regulation of cell proliferation PDGFRA;HTR1A;FLT3;HTR2A;PTGS2;HMGCR;CHRNA7;KIT GO:0007155| cell adhesion CYP1B1;RET GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RET GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;RET;CAT;RAD51;CYP1A2;PTGS2;SOD1;HTR2A GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;KIT GO:0010243| response to organic nitrogen PTGS2;FLT3;TRPV1 GO:0048265| response to pain RET;TRPV1;TRPA1 GO:0051897| positive regulation of protein kinase B signaling cascade MET;KIT;GPX1;PDGFRA GO:0060326| cell chemotaxis ABCC1;PDGFRA;KIT GO:0061298| retina vasculature development in camera-type eye PDGFRA;CYP1B1 GO:0006687| glycosphingolipid metabolic process SMPD1;KIT GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FLT3;CAT;KIT;PDGFRA GO:0051260| protein homooligomerization GLRA3;RAD51;ACAT1;GLRA1 GO:0031100| organ regeneration FLT3;PPARG GO:0046686| response to cadmium ion CAT;KIT GO:0000187| activation of MAPK activity CHRNA7;KIT;SOD1;PLA2G1B GO:0001541| ovarian follicle development KIT;SOD1 GO:0031532| actin cytoskeleton reorganization TRPV4;KIT GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;PDGFRA;TRPV4;ALOX15 GO:0010628| positive regulation of gene expression KIT;RET;TRPV4 GO:0007283| spermatogenesis KIT;SOD1;CNR1 GO:0001657| ureteric bud development CAT;RET GO:0043406| positive regulation of MAP kinase activity KIT;FLT3;HTR2A 20369:[DB14011 DB07920] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07920|N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;PPARG;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MMP12 GO:0042060| wound healing OPRM1;MMP12;ALOX15 GO:0010628| positive regulation of gene expression TRPV4;MMP12 20370:[DB14011 DB03809] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03809|9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine HSP90AA1 common genes common pathways GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HSP90AA1 GO:0009409| response to cold TRPM8;TRPA1;PPARG;HSP90AA1 GO:0009408| response to heat TRPV1;HSP90AA1;TRPV2;SOD1;TRPV3 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;HSP90AA1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A 20371:[DB14011 DB03828] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03828|RU78299 SRC common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0007155| cell adhesion CYP1B1;SRC GO:0045087| innate immune response SRC;PPARG GO:0009615| response to virus CYP1A1;SRC GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;SRC GO:0016236| macroautophagy SRC;VDAC1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;SRC;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0002376| immune system process SRC;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;SRC;CHRNA7;TRPV4;ALOX15 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;SRC;TRPA1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2;SRC GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC;GPX1 GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction VDAC1;SRC;HTR2A GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;SRC GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;SRC GO:0070542| response to fatty acid SRC;CAT;PTGS2 GO:0045453| bone resorption GPR55;SRC GO:0008283| cell proliferation CYP1A1;HTR1A;SRC;GPX1 20372:[DB14011 DB02296] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02296|Isoamyl alcohol REN common genes common pathways GO:0048469| cell maturation PPARG;REN GO:0008217| regulation of blood pressure PPARG;REN;PTGS2;SOD1;PTGS1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;IDO1;REN;CYP1A1 GO:0001822| kidney development CAT;REN GO:0035902| response to immobilization stress CYP1A2;REN;PPARG;CYP1A1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;REN;CYP1A1;PPARG;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0051591| response to cAMP REN;AANAT GO:0010033| response to organic substance REN;TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 20373:[DB14011 DB04098] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04098|Balanol PRKACA common genes common pathways GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2;PRKACA 20374:[DB14011 DB02818] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02818|Iodo-Willardiine GRIA2 common genes common pathways GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;TRPV1;GLRA3;OPRM1;CHRNA7;GRIA2;SLC29A1 GO:0034220| ion transmembrane transport TRPA1;GLRA1;TRPV1;GLRB;GLRA3;GRIA2;CHRNA7 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;GLRA3;GRIA2;CACNA1G;GLRA1;VDAC1;GLRB GO:0006811| ion transport CHRNA7;TRPV2;GRIA2;GLRA3;CACNA1H;TRPV3;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;TRPA1;GLRA1;CACNA1G GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GRIA2;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 20375:[DB14011 DB02240] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02240|Quinacrine mustard TPR common genes common pathways GO:0034605| cellular response to heat TRPV1;TRPV4;TPR;PTGS2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TPR;PPARG;TRPV1;TRPV4 GO:0016032| viral reproduction TPR;HTR2A;VDAC1 GO:0042307| positive regulation of protein import into nucleus PTGS2;TPR 20376:[DB14011 DB03015] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03015|6-Hydroxy-1,6-Dihydro Purine Nucleoside ADA common genes common pathways GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT;ADA GO:0043278| response to morphine OPRM1;CNR1;ADA GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0030324| lung development ADA;CYP1A2 GO:0033197| response to vitamin E ADA;CAT GO:0007155| cell adhesion ADA;CYP1B1 GO:0043066| negative regulation of apoptotic process ADA;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0001666| response to hypoxia CYP1A1;ADA;CHRNA7;CAT GO:0007568| aging CYP1A1;ADA;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1 GO:0001889| liver development ACAT1;ADA;CYP1A1 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;ADA;CAT;SOD1 GO:0001890| placenta development PPARG;SOD1;ADA GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 20377:[DB14011 DB01877] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01877|N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide MMP3 common genes common pathways 20378:[DB14011 DB08240] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways GO:0051289| protein homotetramerization CAT;TRPV1;TRPM8;ALDOA;TRPA1;CRYZ GO:0046716| muscle cell homeostasis SOD1;ALDOA GO:0007015| actin filament organization ALDOA;PLA2G1B;TRPV4 GO:0043312| neutrophil degranulation CAT;ALOX5;ALDOA GO:0002576| platelet degranulation ALDOA;SOD1 20379:[DB14011 DB08028] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08028|BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE MMP8 common genes common pathways GO:0043312| neutrophil degranulation MMP8;CAT;ALOX5 20380:[DB14011 DB08697] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08697|4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CACNA1I;PLA2G1B;PLAU;SMPD1;PPARG;GPR18 GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;PLAU 20381:[DB14011 DB06043] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06043|Olaratumab PDGFRA common genes common pathways GO:0016032| viral reproduction VDAC1;PDGFRA;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration PDGFRA;TRPV4;TRPV1;OPRM1;HTR2A GO:0045740| positive regulation of DNA replication PLA2G1B;PDGFRA GO:0048146| positive regulation of fibroblast proliferation PDGFRA;PLA2G1B GO:0042060| wound healing OPRM1;ALOX15;PDGFRA GO:0008284| positive regulation of cell proliferation PDGFRA;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0061298| retina vasculature development in camera-type eye PDGFRA;CYP1B1 GO:0060326| cell chemotaxis PDGFRA;ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PDGFRA GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;PDGFRA GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;PDGFRA;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 20382:[DB14011 DB08513] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08513|[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID MAPK1;INSR;IRS1 common genes common pathways GO:0001934| positive regulation of protein phosphorylation INSR;CHRNA7 GO:0007268| synaptic transmission OPRM1;OPRD1;HTR2A;GLRA3;GLRB;VDAC1;MAPK1;CACNA1G;GLRA1 GO:0016032| viral reproduction MAPK1;VDAC1;HTR2A GO:0045821| positive regulation of glycolysis HTR2A;INSR GO:0006351| transcription, DNA-dependent MAPK1;PPARG GO:0019233| sensory perception of pain HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1;TRPA1;MAPK1;TRPV1 GO:0007507| heart development PPARG;MAPK1 GO:0035556| intracellular signal transduction MAPK1;INSR;PLA2G1B GO:0032868| response to insulin stimulus IRS1;CAT;AANAT;TRPV4 GO:0009636| response to toxin GPX1;CAT;CYP1B1;MAPK1;CYP1A1 GO:0043627| response to estrogen stimulus MAPK1;PPARG GO:0071276| cellular response to cadmium ion MAPK1;CYP1A2;SOD1 GO:0045740| positive regulation of DNA replication INSR;PLA2G1B GO:0007613| memory INSR;CHRNA7;HTR2A;CNR1;PTGS2 GO:0032869| cellular response to insulin stimulus IRS1;INSR;PPARG;PLA2G1B GO:0043434| response to peptide hormone stimulus TRPV1;IRS1 GO:0007165| signal transduction CHRNA7;IRS1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;MAPK1;SMPD1;PPARG;GPR18 GO:0014065| phosphatidylinositol 3-kinase cascade IRS1;HTR2A GO:0006355| regulation of transcription, DNA-dependent INSR;MAPK1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;INSR;MAPK1 GO:0035094| response to nicotine MAPK1;CHRNA7;CNR1 GO:0051897| positive regulation of protein kinase B signaling cascade IRS1;GPX1;INSR GO:0007612| learning PTGS2;INSR;VDAC1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MAPK1;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0007611| learning or memory MAPK1;CHRNA7;CNR1 GO:0043312| neutrophil degranulation MAPK1;ALOX5;CAT GO:0008284| positive regulation of cell proliferation MAPK1;INSR;PTGS2;IRS1;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0000187| activation of MAPK activity PLA2G1B;INSR;MAPK1;CHRNA7;SOD1 GO:0006915| apoptotic process GPX1;MAPK1;VDAC1 GO:0071356| cellular response to tumor necrosis factor TRPV1;MAPK1 GO:0010628| positive regulation of gene expression TRPV4;MAPK1 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG;INSR GO:0071363| cellular response to growth factor stimulus TRPV1;INSR;CAT;OPRD1 GO:0042593| glucose homeostasis TRPV4;PPARG;INSR;CNR1;IRS1 GO:0048538| thymus development SOD1;MAPK1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;INSR 20383:[DB14011 DB03848] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03848|Benzenesulfinic acid NR1H2 common genes common pathways GO:0010745| negative regulation of macrophage derived foam cell differentiation NR1H2;PPARG GO:0010887| negative regulation of cholesterol storage NR1H2;PPARG GO:0055088| lipid homeostasis NR1H2;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway NR1H2;PPARG GO:0010629| negative regulation of gene expression NR1H2;OPRD1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NR1H2 GO:0043401| steroid hormone mediated signaling pathway NR1H2;PPARG GO:0006351| transcription, DNA-dependent NR1H2;PPARG GO:0010628| positive regulation of gene expression TRPV4;NR1H2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1H2 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1H2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1H2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1H2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NR1H2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;NR1H2;PPARG 20384:[DB14011 DB05964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0009636| response to toxin CYP1A1;CYP1B1;DRD2;GPX1;SLC6A4;CAT GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0014854| response to inactivity CAT;DRD2 GO:0030336| negative regulation of cell migration DRD2;CYP1B1 GO:0007584| response to nutrient PPARG;SLC6A4;CNR1;HMGCR GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;DRD2;PPARG GO:0001975| response to amphetamine CNR2;SOD1;DRD2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7;SLC6A4 GO:1900273| CHRNA7;DRD2 GO:0050482| arachidonic acid secretion DRD2;PLA2G1B GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;PLA2G1B;DRD2;CACNA1I;SMPD1;GPR18;PPARG GO:0007420| brain development ACAT1;SLC6A4 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GLRB;VDAC1;GLRA1;CACNA1G;SLC6A2 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0001964| startle response GLRB;DRD2;GLRA1 GO:0008542| visual learning DRD2;HMGCR GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0045776| negative regulation of blood pressure CNR1;DRD2 GO:0045471| response to ethanol DRD2;CAT;SOD1;CNR1;OPRM1;HMGCR GO:0048678| response to axon injury DRD2;SOD1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0001659| temperature homeostasis TRPV1;DRD2;GPX1;HTR2A GO:0048148| behavioral response to cocaine HTR2A;DRD2 GO:0042136| neurotransmitter biosynthetic process SLC6A4;DAGLA GO:0042310| vasoconstriction HTR1A;SLC6A4 GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;DRD2;TRPV4 GO:0055085| transmembrane transport TRPA1;SLC6A2;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1;TRPV3;CACNA1H;SLC6A4;TRPV2 GO:0042220| response to cocaine OPRM1;CNR1;DRD2;SMPD1 GO:0001666| response to hypoxia DRD2;CYP1A1;CHRNA7;CAT;SLC6A4 GO:0010628| positive regulation of gene expression TRPV4;SLC6A4 GO:0009416| response to light stimulus AANAT;DRD2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;DRD2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SLC6A4;SOD1;PTGS2;CYP1A2 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;DRD2;GPR18;PPARG GO:0032355| response to estradiol stimulus CAT;SLC6A4;CYP1A2;PTGS2 GO:0051209| release of sequestered calcium ion into cytosol TRPV1;DRD2;TRPA1;HTR2A GO:0006810| transport TRPV2;CACNA1I;TRPV1;ABCG2;ABCC1;SLC6A2 GO:0051260| protein homooligomerization ACAT1;SLC6A4;GLRA3;GLRA1 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;TRPM8;DRD2;TRPV4 GO:0042493| response to drug ABCG2;DRD2;TRPA1;PPARG;CYP1A1;SMPD1;SLC6A2;ABCC1;CAT;SLC6A4;HTR2A;SOD1;CYP1A2;PTGS2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0035094| response to nicotine CHRNA7;CNR1;DRD2 GO:0043278| response to morphine DRD2;OPRM1;CNR1 GO:0048265| response to pain TRPA1;SLC6A2;TRPV1 GO:0007623| circadian rhythm AANAT;SLC6A4 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;DRD2;GLRA1 GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0007626| locomotory behavior DRD2;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;PLA2G1B;PPARG GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0071300| cellular response to retinoic acid SLC6A4;PPARG GO:0007628| adult walking behavior GLRA1;DRD2;GLRB GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 20385:[DB14011 DB01262] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01262|Decitabine DNMT1;DCK common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;DNMT1 GO:0006139| nucleobase-containing compound metabolic process DCK;SLC29A1 GO:0042127| regulation of cell proliferation DNMT1;PTGS1;PTGS2 GO:0071230| cellular response to amino acid stimulus DNMT1;GLRA1 GO:0032259| methylation CYP1A2;DNMT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;DNMT1 GO:0006355| regulation of transcription, DNA-dependent DNMT1;PPARG GO:0010468| regulation of gene expression CYP1A2;DNMT1 GO:0010628| positive regulation of gene expression TRPV4;DNMT1 GO:0045892| negative regulation of transcription, DNA-dependent DNMT1;PPARG 20386:[DB14011 DB05129] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways GO:0048511| rhythmic process PPARG;TOP2A;AANAT;TOP1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;TOP1;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TOP2A;PLA2G1B GO:0007623| circadian rhythm TOP1;AANAT GO:0016032| viral reproduction TOP1;HTR2A;VDAC1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;TOP2A;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 20387:[DB14011 DB07359] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07359|3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide GCK common genes common pathways GO:0070509| calcium ion import CACNA1G;CACNA1I;TRPV4;CACNA1H;GCK GO:0042593| glucose homeostasis GCK;CNR1;TRPV4;PPARG GO:0008152| metabolic process SMPD1;GCK;ACAT1 GO:0032869| cellular response to insulin stimulus GCK;PLA2G1B;PPARG GO:0050796| regulation of insulin secretion CNR1;GCK 20388:[DB14011 DB07753] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0043312| neutrophil degranulation CAT;TTR;ALOX5 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;TTR;TRPV2 20389:[DB14011 DB07875] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07875|5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 20390:[DB14011 DB01034] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways GO:0008152| metabolic process SMPD1;FASN;ACAT1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;FASN;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;FASN;PLA2G1B GO:0001649| osteoblast differentiation CAT;FASN GO:0006631| fatty acid metabolic process FASN;ALOX15;PTGS2;PTGS1 GO:0055114| oxidation-reduction process FASN;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP2C9;CYP1A1;CRYZ;ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0045540| regulation of cholesterol biosynthetic process FASN;HMGCR 20391:[DB14011 DB07555] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways GO:0007155| cell adhesion CYP1B1;ACHE GO:0007517| muscle organ development ACHE;CACNA1H GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0051262| protein tetramerization CAT;HMGCR;ACHE GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0008283| cell proliferation GPX1;HTR1A;ACHE;CYP1A1 20392:[DB14011 DB07011] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways GO:0001666| response to hypoxia CYP1A1;NOS2;CAT;CHRNA7 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;NOS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;NOS2;CYP1A1 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;NOS2;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0050796| regulation of insulin secretion NOS2;CNR1 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0010629| negative regulation of gene expression OPRD1;NOS2 20393:[DB14011 DB04600] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04600|4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE CA2 common genes common pathways GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CA2;SOD1;CYP1A2;PTGS2 GO:0001822| kidney development CAT;CA2 GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 20394:[DB14011 DB08773] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08773|RALOXIFENE CORE ESR1;NCOA2 common genes common pathways GO:0048511| rhythmic process AANAT;NCOA2;PPARG GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;NCOA2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;PPARG;PLA2G1B;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;NCOA2;PPARG;TRPV1;TRPV4 GO:0007623| circadian rhythm NCOA2;AANAT GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;ESR1;OPRD1;OPRM1;CNR2 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;NCOA2;CYP1A1;PPARG GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;ESR1;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG;NCOA2 20395:[DB14011 DB07491] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07491|5-amino-2,4,6-tribromobenzene-1,3-dicarboxylic acid PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 20396:[DB14011 DB03867] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03867|Meta-Nitro-Tyrosine GSR common genes GSR common pathways GO:0098869| GSR;PTGS2;CAT;GPX1;PTGS1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;GSR GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0006749| glutathione metabolic process GPX1;SOD1;GSR GO:0045454| cell redox homeostasis GSR;GPX1 20397:[DB14011 DB08422] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08422|[PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;F2 20398:[DB14011 DB03568] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03568|Butyric Acid BCHE;BCHE common genes common pathways GO:0042493| response to drug ABCG2;ABCC1;SMPD1;BCHE;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;BCHE;PPARG GO:0007584| response to nutrient PPARG;BCHE;CNR1;HMGCR GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 20399:[DB14011 DB01861] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;GYG1 20400:[DB14011 DB09137] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09137|Technetium Tc-99m mebrofenin SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;SLCO1B3;SLCO1B1;CACNA1H;TRPV3;TRPV2 GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;CACNA1H;TRPV3;SLCO1B3;GLRA3;SLCO1B1 20401:[DB14011 DB03046] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03046|7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0007165| signal transduction PLAU;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0001666| response to hypoxia CHRNA7;CAT;PLAU;CYP1A1 GO:0042127| regulation of cell proliferation PLAU;PTGS1;PTGS2 GO:0043312| neutrophil degranulation ALOX5;CAT;PLAU 20402:[DB14011 DB01692] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01692|Dithioerythritol prfA;TK1 common genes common pathways GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPV1;TRPM8;TK1;CAT GO:0006139| nucleobase-containing compound metabolic process SLC29A1;TK1 20403:[DB14011 DB03884] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03884|Phenylpyruvic acid HAO1;SLC16A3 common genes common pathways GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2;HAO1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2;ABCC1;CACNA1G;SLC16A3;TRPA1 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;HAO1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9 20404:[DB14011 DB02082] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways 20405:[DB14011 DB05831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05831|ING-1 EPCAM common genes common pathways GO:0001657| ureteric bud development EPCAM;CAT GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;EPCAM GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;EPCAM 20406:[DB14011 DB06995] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PLA2G1B;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MET GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;MET;CNR2;OPRD1;CHRNA7 GO:0008283| cell proliferation GPX1;HTR1A;MET;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway MET;TRPA1;TRPV1 20407:[DB14011 DB07929] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07929|N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE NR1H3;RXRB common genes common pathways GO:0050728| negative regulation of inflammatory response CNR2;NR1H3 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRB;NR1H3 GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRB;NR1H3 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1H3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;PPARG;NR1H3;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;NR1H3;PPARG GO:0043277| apoptotic cell clearance NR1H3;ALOX15 GO:0042752| regulation of circadian rhythm NR1H3;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1H3;RXRB;PPARG GO:0006351| transcription, DNA-dependent RXRB;PPARG;NR1H3 GO:0010887| negative regulation of cholesterol storage PPARG;NR1H3 GO:0055088| lipid homeostasis NR1H3;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway NR1H3;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation NR1H3;PPARG 20408:[DB14011 DB07479] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways GO:0006954| inflammatory response POLB;PTGS1;ALOX5;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0045471| response to ethanol POLB;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0010332| response to gamma radiation POLB;GPX1 GO:0055093| response to hyperoxia CAT;POLB;CYP1A1 GO:0006915| apoptotic process VDAC1;GPX1;POLB GO:0007568| aging CYP1A1;POLB;CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD 20409:[DB14011 DB03784] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03784|Elaidoylamide PLA2G2A common genes common pathways GO:0006644| phospholipid metabolic process PLA2G1B;PLA2G2A;NAPEPLD GO:0070374| positive regulation of ERK1 and ERK2 cascade PLA2G2A;ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0016042| lipid catabolic process NAPEPLD;PLA2G1B;PLA2G2A;DAGLA GO:0036152| PLA2G1B;PLA2G2A GO:0050830| defense response to Gram-positive bacterium PLA2G2A;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2A GO:0036151| PLA2G2A;PLA2G1B GO:0036150| PLA2G1B;PLA2G2A GO:0050482| arachidonic acid secretion PLA2G2A;PLA2G1B GO:0050729| positive regulation of inflammatory response TRPV4;PLA2G2A GO:0006629| lipid metabolic process ALOX15;PLA2G2A;CYP2D6;DAGLA;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;PTGS2;CYP1A2;HMGCR GO:0036148| PLA2G2A;PLA2G1B GO:0036149| PLA2G2A;PLA2G1B 20410:[DB14011 DB06199] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06199|Atrasentan EDNRA common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;EDNRA;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1 GO:0006939| smooth muscle contraction EDNRA;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;EDNRA GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;EDNRA;HTR2A;OPRM1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;EDNRA GO:0008283| cell proliferation CYP1A1;EDNRA;HTR1A;GPX1 GO:0007507| heart development PPARG;EDNRA GO:0042310| vasoconstriction EDNRA;HTR1A GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;EDNRA;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0015758| glucose transport EDNRA;PLA2G1B GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EDNRA GO:0001666| response to hypoxia CYP1A1;EDNRA;CHRNA7;CAT GO:0014824| artery smooth muscle contraction HTR2A;EDNRA 20411:[DB14011 DB01741] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01741|CRA_17693 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20412:[DB14011 DB08130] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways GO:0000187| activation of MAPK activity SOD1;CHRNA7;MAP2K1;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;MAP2K1;ALOX15;TRPV4 GO:0010628| positive regulation of gene expression TRPV4;MAP2K1 GO:0048538| thymus development MAP2K1;SOD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;MAP2K1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;MAP2K1;PPARG;CYP1B1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;MAP2K1;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0010629| negative regulation of gene expression OPRD1;MAP2K1 GO:0007507| heart development MAP2K1;PPARG 20413:[DB14011 DB00028] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;C3;CYP3A4;NAPEPLD;NAAA;PTGS1;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;C5 GO:0010575| positive regulation vascular endothelial growth factor production C3;C5;PTGS2;CYP1B1 GO:0006955| immune response C3;CNR2;OPRD1;FCGR2C;FCGR1B;FCGR3A;FCGR1A;FCGR2B;FCGR3B GO:0016032| viral reproduction VDAC1;FCGR2B;HTR2A GO:0006954| inflammatory response TRPV1;IDO1;C4A;ALOX15;FCGR2B;PTGS1;ALOX5;C4B;CNR2;PTGS2;C3;C5 GO:0001934| positive regulation of protein phosphorylation CHRNA7;C3 GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0007165| signal transduction FCGR2C;OPRD1;OPRM1;CNR2;C3;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;FCGR2B;PLA2G1B;CACNA1I;FCGR1A GO:0043312| neutrophil degranulation FCGR3B;FCGR2A;C3;CAT;ALOX5 GO:0045087| innate immune response C4B;C3;C5;FCGR1A;C4A;PPARG GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0060326| cell chemotaxis C5;ABCC1 GO:0006631| fatty acid metabolic process C3;PTGS2;PTGS1;ALOX15 GO:0002376| immune system process IDO1;C4A;FCGR1A;FCGR2A;C4B;FCGR1B;C3;C5 GO:0007186| G-protein coupled receptor signaling pathway C3;HTR2A;CNR1;GPR12;GPR55;C5;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1;C5 GO:0045766| positive regulation of angiogenesis C5;C3;CHRNA7;CYP1B1 20414:[DB14011 DB04622] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;QPCT 20415:[DB14011 DB06196] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways GO:1902219| BDKRB2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;BDKRB2;OPRM1;CNR2;GPR18;PPARG GO:0042311| vasodilation BDKRB2;GPX1 GO:0043312| neutrophil degranulation CAT;ALOX5;ANPEP GO:0050482| arachidonic acid secretion PLA2G1B;BDKRB2 GO:0006939| smooth muscle contraction BDKRB2;HTR2A GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;ANPEP;OPRD1;BDKRB2;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0046718| entry of virus into host cell ANPEP;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;HTR2A;BDKRB2;OPRM1 GO:0008217| regulation of blood pressure ANPEP;PTGS2;SOD1;PTGS1;PPARG GO:0042310| vasoconstriction BDKRB2;HTR1A GO:0007166| cell surface receptor linked signaling pathway BDKRB2;TRPA1;TRPV1 GO:0001525| angiogenesis CYP1B1;PTGS2;ANPEP GO:0016032| viral reproduction VDAC1;HTR2A;ANPEP GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;ALOX5;PTGS1;PTGS2;CNR2;BDKRB2 20416:[DB14011 DB14057] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14057|Valinomycin ABCB11 common genes common pathways GO:0035725| sodium ion transmembrane transport CACNA1H;ABCB11;CACNA1I;CACNA1G GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3;ABCB11 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;ABCB11;TRPV2 20417:[DB14011 DB06980] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06980|(2S)-2-(1H-indol-3-yl)hexanoic acid SKP1 common genes common pathways GO:0006879| cellular iron ion homeostasis SOD1;SKP1;ABCG2 20418:[DB14011 DB07139] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07139|3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0022900| electron transport chain CYP1A2;AKR1B1;IDO1;GSR GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;AKR1B1;CYP1A1;CYP2C9;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0010033| response to organic substance AKR1B1;PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 20419:[DB14011 DB07760] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07760|3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid UNG common genes common pathways GO:0016032| viral reproduction UNG;VDAC1;HTR2A GO:0043066| negative regulation of apoptotic process UNG;SOD1;HMGCR;PTGS2;CAT;GPX1 20420:[DB14011 DB06900] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways GO:0065009| regulation of molecular function PRSS8;TRPV1 20421:[DB14011 DB06971] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06971|N-{2-[(4'-CYANO-1,1'-BIPHENYL-4-YL)OXY]ETHYL}-N'-HYDROXY-N-METHYLUREA MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 20422:[DB14011 DB00218] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes CYP1A2 common pathways GO:0048511| rhythmic process PPARG;TOP2A;AANAT GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;PPARG;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0042752| regulation of circadian rhythm PPARG;TOP2A GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;TOP2A;SMPD1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 20423:[DB14011 DB13530] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13530|Mepindolol CYP2D6 common genes CYP2D6 common pathways GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 20424:[DB14011 DB08842] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08842|Acetylcarnitine SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCG2;ABCC1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;SLC22A5;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC22A5;TRPV2;ABCC1;CACNA1G;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;TRPM8;ABCG2 20425:[DB14011 DB03708] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways GO:0008152| metabolic process ACAT1;PAPSS1;SMPD1 20426:[DB14011 DB05199] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05199|LX1031 TPH1 common genes common pathways GO:0045600| positive regulation of fat cell differentiation HTR2A;TPH1;PPARG GO:0046219| indolalkylamine biosynthetic process TPH1;AANAT GO:0007623| circadian rhythm TPH1;AANAT GO:0035902| response to immobilization stress TPH1;PPARG;CYP1A1;CYP1A2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;TPH1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1 20427:[DB14011 DB05882] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05882|CHF 4227 ESR1;ESR2 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2;OPRM1;TRPV1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;ESR2;TRPV4;TRPV1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;PLA2G1B;PPARG;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;ESR1;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;ESR2;SMPD1;PPARG;GPR18 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ESR1;HTR2A;OPRM1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG 20428:[DB14011 DB08249] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0031000| response to caffeine DHODH;PPARG GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;DHODH;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0055114| oxidation-reduction process CAT;DHODH;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0042594| response to starvation DHODH;ACAT1;PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;DHODH;ACAT1;AANAT;CYP1A1;PPARG;TRPA1 GO:0007565| female pregnancy IDO1;DHODH GO:0007595| lactation DHODH;SLC29A1 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;DHODH;CNR1;SOD1;PTGS2 20429:[DB14011 DB13165] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway ROCK1;GPR18;PPARG;ROCK2;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0006915| apoptotic process GPX1;ROCK1;VDAC1 GO:0048511| rhythmic process AANAT;ROCK2;PPARG GO:0010628| positive regulation of gene expression ROCK2;ROCK1;TRPV4 GO:0043312| neutrophil degranulation ROCK1;CAT;ALOX5 GO:0016525| negative regulation of angiogenesis ROCK1;ROCK2;PPARG GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;ROCK1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0006939| smooth muscle contraction ROCK2;ROCK1;HTR2A GO:0035556| intracellular signal transduction ROCK2;ROCK1;PLA2G1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;ROCK2 GO:0043524| negative regulation of neuron apoptosis ROCK1;SOD1 GO:0042752| regulation of circadian rhythm ROCK2;PPARG GO:1902430| CHRNA7;ROCK1 20430:[DB14011 DB04779] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04779|ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;LCT 20431:[DB14011 DB03346] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;TTR GO:0008210| estrogen metabolic process CYP1B1;SULT1E1 GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;SULT1E1;CYP1A1;CYP2C9;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;TTR;TRPV2 GO:0042572| retinol metabolic process CYP1B1;TTR GO:0045600| positive regulation of fat cell differentiation PPARG;SULT1E1;HTR2A GO:0001523| retinoid metabolic process NAPEPLD;TTR 20432:[DB14011 DB00686] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0008283| cell proliferation HTR1A;FGF1;GPX1;CYP1A1 GO:0051781| positive regulation of cell division FGF4;FGF2;FGF1;CAT GO:0043537| negative regulation of blood vessel endothelial cell migration FGF2;PPARG GO:0065009| regulation of molecular function FGF4;TRPV1 GO:0007165| signal transduction FGF1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;FGF2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;FGF4 GO:0001934| positive regulation of protein phosphorylation CHRNA7;FGF1;FGF4 GO:0061045| negative regulation of wound healing FGF2;HMGCR GO:0001525| angiogenesis CYP1B1;FGF1;FGF2;PTGS2 GO:0007399| nervous system development SMPD1;GLRB;FGF2 GO:0000187| activation of MAPK activity CHRNA7;FGF2;FGF1;SOD1;PLA2G1B GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;FGF2;FGF1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;FGF2;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;FGF4;ALOX15 GO:0010628| positive regulation of gene expression FGF4;TRPV4 GO:0043406| positive regulation of MAP kinase activity FGF2;FGF1;HTR2A GO:0034605| cellular response to heat TRPV1;TRPV4;FGF1;PTGS2 GO:0051209| release of sequestered calcium ion into cytosol FGF2;HTR2A;TRPA1;TRPV1 GO:0010468| regulation of gene expression CYP1A2;FGF4 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;FGF2;GPX1;FGF4 GO:0042060| wound healing OPRM1;FGF2;ALOX15 GO:0030324| lung development FGF1;CYP1A2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;FGF4 GO:0008284| positive regulation of cell proliferation FGF4;HMGCR;FGF2;PTGS2;HTR2A;HTR1A;FGF1;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;FGF4;FGF1;FGF2 20433:[DB14011 DB07208] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes PPARG common pathways GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9;PTGS1;NAAA;GPX1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;GPR18;PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0045087| innate immune response PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 20434:[DB14011 DB09093] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR;ALB GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB GO:0001895| retina homeostasis ALB;SOD1 20435:[DB14011 DB07744] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;CASP1;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7 GO:0006919| activation of caspase activity PPARG;CASP1 GO:0050727| regulation of inflammatory response PTGS2;CASP1 GO:0071260| cellular response to mechanical stimulus CASP1;PTGS2 GO:0006915| apoptotic process GPX1;CASP1;VDAC1 GO:0001666| response to hypoxia CHRNA7;CAT;CASP1;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;CASP1;IDO1;CNR1;PTGS2;CNR2;CYP1A2;OPRM1 20436:[DB14011 DB13443] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13443|Esatenolol CYP2D6 common genes CYP2D6 common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process DAGLA;CYP2D6;ALOX15;CYP1B1;FAAH GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006629| lipid metabolic process CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;NAAA;PTGS1;GPX1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0051100| negative regulation of binding CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 20437:[DB14011 DB05642] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0045471| response to ethanol HTR3A;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0007268| synaptic transmission HTR3A;VDAC1;GLRB;SLC6A2;CACNA1G;GLRA1;OPRD1;OPRM1;HTR2A;GLRA3 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;HTR3A;PLA2G1B;CACNA1I GO:0006811| ion transport GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;HTR3A GO:0048265| response to pain SLC6A2;TRPA1;TRPV1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SLC6A2;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;TRPV1;HTR3A GO:0006810| transport ABCG2;TRPV1;CACNA1I;SLC6A2;ABCC1;TRPV2 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;HTR3A;TRPV1;GLRB;GLRA1;TRPA1 GO:0055085| transmembrane transport VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;SLC6A2;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0042220| response to cocaine CNR1;OPRM1;HTR3A;SMPD1 20438:[DB14011 DB08584] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG;PLA2G1B GO:0051897| positive regulation of protein kinase B signaling cascade MET;GPX1 GO:0007165| signal transduction CHRNA7;OPRM1;MET;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0008283| cell proliferation GPX1;MET;HTR1A;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway MET;TRPA1;TRPV1 20439:[DB14011 DB04859] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04859|Zanapezil ACHE common genes common pathways GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion ACHE;CYP1B1 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0008283| cell proliferation HTR1A;ACHE;GPX1;CYP1A1 20440:[DB14011 DB12548] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12548|Sparsentan AGT;EDNRA common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger AGT;OPRD1;OPRM1;HTR2A GO:0014824| artery smooth muscle contraction EDNRA;HTR2A;AGT GO:0042127| regulation of cell proliferation AGT;PTGS1;PTGS2 GO:0030308| negative regulation of cell growth AGT;PPARG GO:0008284| positive regulation of cell proliferation AGT;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0042311| vasodilation AGT;GPX1 GO:0001822| kidney development CAT;AGT GO:0010666| positive regulation of cardiac muscle cell apoptosis AGT;HMGCR GO:0045893| positive regulation of transcription, DNA-dependent AGT;PPARG GO:0016525| negative regulation of angiogenesis PPARG;AGT GO:0007568| aging AGT;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CYP1A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;AGT GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;AGT GO:0007186| G-protein coupled receptor signaling pathway EDNRA;PPARG;GPR18;AGT;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0043085| positive regulation of catalytic activity AGT;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process AGT;PTGS2;OPRM1;TRPV1 GO:0015758| glucose transport PLA2G1B;EDNRA GO:0007202| activation of phospholipase C activity HTR2A;GPR55;AGT;EDNRA GO:0001666| response to hypoxia CHRNA7;CAT;EDNRA;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway AGT;TRPA1;TRPV1 GO:0007507| heart development PPARG;EDNRA GO:0002027| regulation of heart rate CACNA1G;AGT GO:0071260| cellular response to mechanical stimulus AGT;PTGS2 GO:0042310| vasoconstriction EDNRA;HTR1A;AGT GO:0007565| female pregnancy AGT;IDO1 GO:0010629| negative regulation of gene expression AGT;OPRD1 GO:0051924| regulation of calcium ion transport OPRD1;AGT GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation AGT;HTR2A GO:0010976| positive regulation of neuron projection development AGT;CNR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AGT;CAT GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;EDNRA;AGT;HTR2A;OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDNRA;OPRD1;OPRM1 GO:0050729| positive regulation of inflammatory response AGT;TRPV4 GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;CNR1;HMGCR;AGT GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;EDNRA;PPARG;SMPD1 GO:0065009| regulation of molecular function AGT;TRPV1 GO:0006939| smooth muscle contraction EDNRA;HTR2A GO:0001819| positive regulation of cytokine production SOD1;AGT GO:0045777| positive regulation of blood pressure CNR1;AGT GO:0008283| cell proliferation GPX1;HTR1A;EDNRA;CYP1A1 GO:0032930| positive regulation of superoxide anion generation SOD1;AGT GO:0008217| regulation of blood pressure EDNRA;PPARG;PTGS1;AGT;SOD1;PTGS2 GO:0048146| positive regulation of fibroblast proliferation AGT;PLA2G1B 20441:[DB14011 DB07269] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 20442:[DB14011 DB00792] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00792|Tripelennamine HRH1;CYP2D6 common genes CYP2D6 common pathways GO:0006954| inflammatory response PTGS2;CNR2;HRH1;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0008542| visual learning HMGCR;HRH1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0006629| lipid metabolic process PPARG;CYP2C9;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0051100| negative regulation of binding CYP2D6 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;HRH1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;HRH1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0007613| memory HTR2A;CNR1;HRH1;PTGS2;CHRNA7 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0019369| arachidonic acid metabolic process CYP1B1;DAGLA;CYP2D6;ALOX15;FAAH GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;HTR2A GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;HRH1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;GPR18;PPARG GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP3A7;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1 20443:[DB14011 DB14070] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14070|HM-30181 ABCB1 common genes common pathways GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCB1;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0006810| transport TRPV2;ABCC1;TRPV1;CACNA1I;ABCB1;ABCG2 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 20444:[DB14011 DB04447] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04447|1,4-Dithiothreitol acpS;hisD;aroE;LGALS1;CAMK2A;rpmA;ALDH1A1;TRPM7;moaA;MSRA;AXIN1;PPIB;thyA;TPI1;GSTZ1;HMGCR;prfA common genes HMGCR common pathways GO:0006694| steroid biosynthetic process CYP17A1;HMGCR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;MSRA;CAT;ALOX5;PTGS1;GPX1;ALDH1A1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0035900| response to isolation stress NAPEPLD;LGALS1 GO:0010666| positive regulation of cardiac muscle cell apoptosis HMGCR;CAMK2A GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;LGALS1;CAT GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AXIN1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;LGALS1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR GO:0071333| cellular response to glucose stimulus SLC29A1;LGALS1 GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR GO:0006695| cholesterol biosynthetic process HMGCR GO:0046330| positive regulation of JNK cascade TRPV4;AXIN1 GO:0008203| cholesterol metabolic process CAT;HMGCR GO:0043407| negative regulation of MAP kinase activity SMPD1;HMGCR GO:0051262| protein tetramerization TRPM7;HMGCR;CAT GO:0010977| negative regulation of neuron projection development TRPV4;LGALS1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G;TRPV2;TRPV3;TRPM7;CACNA1H GO:0045540| regulation of cholesterol biosynthetic process HMGCR GO:0008299| isoprenoid biosynthetic process HMGCR GO:0006915| apoptotic process LGALS1;GPX1;VDAC1;AXIN1 GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSTZ1;GSR GO:0006979| response to oxidative stress MSRA;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0007568| aging SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0008542| visual learning HMGCR GO:0051092| positive regulation of NF-kappaB transcription factor activity CAMK2A;CAT;PLA2G1B GO:0006816| calcium ion transport CAMK2A;TRPV2;CHRNA7;TRPV3;TRPM7;CACNA1H;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0045445| myoblast differentiation LGALS1;HMGCR GO:0001934| positive regulation of protein phosphorylation CHRNA7;AXIN1 GO:0007399| nervous system development CAMK2A;GLRB;SMPD1 GO:0042572| retinol metabolic process ALDH1A1;CYP1B1 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;GPX1;NAAA;PTGS1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0016126| sterol biosynthetic process HMGCR GO:0035556| intracellular signal transduction PLA2G1B;CAMK2A GO:0008152| metabolic process ALDH1A1;ACAT1;TPI1;GSTZ1;SMPD1 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1 GO:0048678| response to axon injury LGALS1;SOD1 GO:0061045| negative regulation of wound healing HMGCR GO:0006812| cation transport TRPM8;TRPM7 GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0006749| glutathione metabolic process GSTZ1;GSR;GPX1;SOD1 GO:0001523| retinoid metabolic process NAPEPLD;ALDH1A1 GO:0048643| positive regulation of skeletal muscle tissue development HMGCR GO:0010664| negative regulation of striated muscle cell apoptosis HMGCR GO:0006811| ion transport VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;TRPM7;CACNA1H;TRPV3;GLRA3 GO:0007165| signal transduction LGALS1;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;PLA2G1B;CACNA1I;AXIN1;SMPD1;GPR18;PPARG GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;AXIN1 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;CACNA1H;OPRM1;TRPM7;TRPV3;TRPM8;TRPV1;CACNA1I;TRPV4;TRPA1;CACNA1G GO:0015936| coenzyme A metabolic process HMGCR;ACAT1 GO:0006743| ubiquinone metabolic process HMGCR GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG 20445:[DB14011 DB05736] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05736|MIV-701 CTSK common genes common pathways GO:0045453| bone resorption CTSK;GPR55 GO:1903146| VDAC1;CTSK 20446:[DB14011 DB07115] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 20447:[DB14011 DB03477] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes PTGS2 common pathways GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging CYP1A1;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| GSR;PTGS1;GPX1;CAT;PTGS2 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;PTGS2;CYP1A2 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0071498| cellular response to fluid shear stress PTGS2 20448:[DB14011 DB05295] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05295|Eldecalcitol VDR common genes common pathways GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG GO:0006351| transcription, DNA-dependent PPARG;VDR GO:0007595| lactation SLC29A1;VDR GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;TRPV3;CACNA1H;CHRNA7;VDR;TRPV2 GO:0007165| signal transduction VDR;CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;VDR;PTGS2;OPRM1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;VDR GO:0006355| regulation of transcription, DNA-dependent VDR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter VDR;PPARG GO:0046697| decidualization VDR;PTGS2 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;VDR;TRPM8;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG GO:0010628| positive regulation of gene expression VDR;TRPV4 20449:[DB14011 DB08566] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process CTRB1;ABCC1 20450:[DB14011 DB01665] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01665|ZK-800270 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20451:[DB14011 DB08935] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08935|Obinutuzumab MS4A1 common genes common pathways 20452:[DB14011 DB03878] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;ABL1 GO:0034599| cellular response to oxidative stress GSR;ABL1;CAT;GPX1;SOD1 GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ABL1 GO:0007155| cell adhesion ABL1;CYP1B1 GO:0045087| innate immune response ABL1;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;ABL1;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0006915| apoptotic process GPX1;ABL1;VDAC1 GO:0048538| thymus development SOD1;ABL1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ABL1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;ABL1;PTGS2;SOD1;CNR1 GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;ABL1;OPRM1;HTR2A 20453:[DB14011 DB05131] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05131|TTP889 F9 common genes common pathways 20454:[DB14011 DB05518] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05518|Managlinat dialanetil FBP1 common genes common pathways GO:0008152| metabolic process SMPD1;FBP1;ACAT1 GO:0051289| protein homotetramerization CAT;FBP1;TRPM8;TRPV1;TRPA1;CRYZ GO:0030308| negative regulation of cell growth PPARG;FBP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;PPARG;TRPV4;TRPV1 20455:[DB14011 DB09257] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09257|Gimeracil DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;PTGS1;GPX1;DPYD;CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 20456:[DB14011 DB07328] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DPP4 20457:[DB14011 DB08705] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08705|6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE PIM1 common genes common pathways GO:0006915| apoptotic process VDAC1;PIM1;GPX1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PIM1;PTGS2;SOD1 GO:0008283| cell proliferation CYP1A1;PIM1;HTR1A;GPX1 20458:[DB14011 DB03434] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways GO:0061844| GNLY;PLA2G1B 20459:[DB14011 DB00429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00429|Carboprost tromethamine PTGER1 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;PTGER1;CNR2;OPRD1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGER1;CNR2;PTGS2;CYP1A1;IDO1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;PTGER1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PPARG;GPR18 20460:[DB14011 DB07899] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process CTRB1;ABCC1 20461:[DB14011 DB03262] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03262|Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide] CA2 common genes common pathways GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CA2;CYP1A2;PTGS2;SOD1 GO:0001822| kidney development CAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 20462:[DB14011 DB09546] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0006810| transport TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1;SLC6A2 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;SLC6A2;ABCC1;CACNA1G GO:0042493| response to drug ABCG2;ABCC1;SLC6A2;SMPD1;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0048265| response to pain SLC6A2;TRPA1;TRPV1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GLRB;VDAC1;GLRA1;CACNA1G;SLC6A2 20463:[DB14011 DB08964] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;PTGER2;CHRNA7;PTGER3;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0071380| cellular response to prostaglandin E stimulus PTGER2;PPARG GO:0031622| positive regulation of fever generation CNR1;PTGER3;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;PTGER3;HTR1A;GPR55;CNR1;GPR12;HTR2A;PTGER2 GO:0008219| cell death PTGER3;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;PTGER3;OPRD1;OPRM1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGER2;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0042127| regulation of cell proliferation PTGS1;PTGER2;PTGS2 20464:[DB14011 DB00981] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0035640| exploration behavior HTR1A;CHRNA4 GO:0035094| response to nicotine CHRNA7;CHRNA4;CNR1;CHRNB2 GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007626| locomotory behavior CHRNB2;CHRNA4;OPRM1;SOD1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNB2;GLRA1;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;CHRNA4;CHRNA7 GO:1905144| CHRNB2;CHRNA7 GO:0001508| regulation of action potential GLRA1;CHRNB2;CACNA1G;CHRNA4 GO:0007612| learning PTGS2;VDAC1;CHRNB2 GO:0060080| regulation of inhibitory postsynaptic membrane potential CHRNA4;GLRA1 GO:0051262| protein tetramerization CAT;HMGCR;ACHE GO:0014059| regulation of dopamine secretion CHRNA4;HTR2A;CHRNB2 GO:0001666| response to hypoxia CYP1A1;CHRNB2;CHRNA7;CAT;CHRNA4 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0042220| response to cocaine SMPD1;CHRNB2;CNR1;OPRM1 GO:0095500| CHRNA4;CHRNA7;CHRNB2 GO:0034220| ion transmembrane transport GLRA1;TRPA1;CHRNB2;GLRB;TRPV1;GLRA3;CHRNA7;CHRNA4 GO:0007605| sensory perception of sound CHRNB2;GPX1;SOD1 GO:0042391| regulation of membrane potential CHRNB2;CACNA1G;GLRA1;GLRB;CACNA1H;CHRNA4 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;CHRNA4;PTGS1;GPX1 GO:0045759| negative regulation of action potential CHRNB2;CNR2;CNR1 GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0008542| visual learning CHRNB2;HMGCR GO:0006816| calcium ion transport CHRNA4;TRPV2;CHRNA7;TRPV3;CACNA1H;CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;CHRNB2;TRPA1 GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;CHRNA4;GLRA1;CACNA1G;VDAC1;GLRB GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0060078| regulation of postsynaptic membrane potential CHRNB2;CHRNA7 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;CHRNB2 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1;CHRNA4;TRPA1;CHRNB2;TRPV1 GO:0042053| regulation of dopamine metabolic process CHRNB2;HTR1A GO:0051291| protein heterooligomerization GLRB;GLRA1;CHRNB2 GO:0008283| cell proliferation CYP1A1;ACHE;HTR1A;GPX1 GO:0006811| ion transport CHRNB2;CACNA1G;TRPA1;GLRA1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA4;CHRNA7 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;CHRNA4;GPR18;PPARG;SMPD1;CHRNB2;CACNA1I;PLA2G1B GO:0006939| smooth muscle contraction HTR2A;CHRNB2 GO:0007613| memory CHRNB2;PTGS2;CNR1;HTR2A;CHRNA7 GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1;CHRNB2 GO:0050890| cognition CHRNA7;CHRNA4;CHRNB2 20465:[DB14011 DB04772] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04772|1-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18;F2 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A 20466:[DB14011 DB05507] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05507|VX-765 CASP1;IL1B common genes common pathways GO:0001934| positive regulation of protein phosphorylation IL1B;CHRNA7 GO:2000778| positive regulation of interleukin-6 secretion IL1B;TRPV4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL1B GO:0006955| immune response CNR2;OPRD1;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IL1B;PLA2G1B GO:0006954| inflammatory response TRPV1;IDO1;IL1B;ALOX15;ALOX5;PTGS1;PTGS2;CNR2 GO:0031622| positive regulation of fever generation PTGS2;CNR1;IL1B GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;IL1B;CYP1B1 GO:0071260| cellular response to mechanical stimulus CASP1;IL1B;PTGS2 GO:0050727| regulation of inflammatory response CASP1;PTGS2 GO:0006919| activation of caspase activity PPARG;CASP1 GO:0008285| negative regulation of cell proliferation CYP1B1;IL1B;PPARG;PTGS2;OPRM1 GO:0051781| positive regulation of cell division IL1B;CAT GO:0050796| regulation of insulin secretion CNR1;IL1B GO:0007566| embryo implantation SOD1;PTGS2;IL1B GO:0034116| positive regulation of heterotypic cell-cell adhesion IL1B;ALOX15 GO:0007165| signal transduction PPARG;GPR18;CASP1;SMPD1;IL1B;CACNA1I;PLA2G1B;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0071407| cellular response to organic cyclic compound IL1B;CYP1B1;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;PPARG GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0046330| positive regulation of JNK cascade IL1B;TRPV4 GO:0071639| positive regulation of monocyte chemotactic protein-1 production IL1B;TRPV4 GO:0001660| fever generation TRPV1;IL1B GO:0032496| response to lipopolysaccharide CYP1A1;CASP1;IDO1;IL1B;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0008284| positive regulation of cell proliferation IL1B;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IL1B;PPARG GO:0006915| apoptotic process GPX1;CASP1;VDAC1;IL1B GO:0000187| activation of MAPK activity CHRNA7;SOD1;IL1B;PLA2G1B GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;IL1B GO:0043407| negative regulation of MAP kinase activity IL1B;SMPD1;HMGCR GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;CASP1 GO:0010628| positive regulation of gene expression TRPV4;IL1B GO:0045429| positive regulation of nitric oxide biosynthetic process IL1B;TRPV1;PTGS2;OPRM1 20467:[DB14011 DB03588] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03588|Diphenylacetic Acid CTSB common genes common pathways GO:0030855| epithelial cell differentiation CTSB;VDAC1;PPARG GO:0046697| decidualization CTSB;PTGS2 GO:0043312| neutrophil degranulation CAT;ALOX5;CTSB GO:0046718| entry of virus into host cell CTSB;HTR2A 20468:[DB14011 DB01133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01133|Tiludronic acid ATP6V1A;PTPN1 common genes common pathways GO:0006879| cellular iron ion homeostasis ABCG2;ATP6V1A;SOD1 GO:0034976| response to endoplasmic reticulum stress PTPN1;ALOX15 GO:0006811| ion transport GLRA3;CACNA1H;TRPV3;CHRNA7;ATP6V1A;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;ATP6V1A;TRPV2 GO:0043407| negative regulation of MAP kinase activity SMPD1;PTPN1;HMGCR GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;ATP6V1A;GLRA3 GO:0031532| actin cytoskeleton reorganization TRPV4;PTPN1 20469:[DB14011 DB08879] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08879|Belimumab TNFSF13B common genes common pathways GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;TNFSF13B GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;TNFSF13B;CACNA1I GO:0006955| immune response OPRD1;CNR2;TNFSF13B GO:0002376| immune system process TNFSF13B;IDO1 GO:0008284| positive regulation of cell proliferation TNFSF13B;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 20470:[DB14011 DB02103] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02103|2-Chlorodideoxyadenosine HSP90B1 common genes common pathways GO:0034976| response to endoplasmic reticulum stress HSP90B1;ALOX15 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2;HSP90B1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HSP90B1;HMGCR;SOD1 GO:0001666| response to hypoxia CYP1A1;HSP90B1;CHRNA7;CAT 20471:[DB14011 DB02134] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02134|Xanthine gpt;CYP1A2 common genes CYP1A2 common pathways GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0010468| regulation of gene expression CYP1A2 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0009403| toxin biosynthetic process CYP1A2 20472:[DB14011 DB07846] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways GO:0008283| cell proliferation CYP1A1;ACHE;HTR1A;GPX1 GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion CYP1B1;ACHE 20473:[DB14011 DB06550] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06550|Bivatuzumab CD44 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;CD44;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;TRPV4 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;CD44;SOD1;GPX1;CAT GO:0043312| neutrophil degranulation CAT;ALOX5;CD44 GO:0007155| cell adhesion CYP1B1;CD44 GO:0033138| positive regulation of peptidyl-serine phosphorylation CD44;PTGS2;OPRD1 GO:0034116| positive regulation of heterotypic cell-cell adhesion CD44;ALOX15 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD44;HTR2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;CD44 20474:[DB14011 DB08023] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08023|N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine MAPK10 common genes common pathways GO:0042752| regulation of circadian rhythm PPARG;MAPK10 GO:0007165| signal transduction PPARG;GPR18;SMPD1;MAPK10;PLA2G1B;CACNA1I;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0000187| activation of MAPK activity CHRNA7;SOD1;MAPK10;PLA2G1B GO:0048511| rhythmic process PPARG;MAPK10;AANAT GO:0009416| response to light stimulus AANAT;MAPK10 GO:0010468| regulation of gene expression MAPK10;CYP1A2 20475:[DB14011 DB05804] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes CYP3A7;PTGS2 common pathways GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP19A1;CRYZ GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0022900| electron transport chain CYP19A1;GSR;IDO1;CYP1A2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0006694| steroid biosynthetic process CYP19A1;CYP17A1;HMGCR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport CACNA1H;SLCO1A2;TRPV3;SLCO1B3;SLCO1B1;SLC22A8;ABCB11;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;SLCO2B1;TRPM8;SLC10A6 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| PTGS2;HMGCR GO:0030282| bone mineralization ALOX15;PTGS2 GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;TRPV2;ABCB11 GO:0046697| decidualization PTGS2 GO:0007568| aging CYP1A1;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;ABCB11;CACNA1H GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP19A1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:1990776| PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0006811| ion transport TRPM8;SLCO2B1;SLC10A6;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;SLCO1B1;GLRA3;SLC22A8;SLCO1B3;SLCO1A2;TRPV3;CACNA1H GO:0009636| response to toxin SLC22A8;GPX1;CAT;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0098656| SLC22A8;VDAC1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 20476:[DB14011 DB04144] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;MDM2;PPARG GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;MDM2 GO:0046677| response to antibiotic MDM2;CYP1A1;SOD1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;MDM2 GO:0071407| cellular response to organic cyclic compound CYP1A1;MDM2;CYP1B1 GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;MDM2;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2 GO:0043278| response to morphine MDM2;CNR1;OPRM1 GO:0071456| cellular response to hypoxia MDM2;SLC29A1;PTGS2;OPRD1 GO:0010468| regulation of gene expression CYP1A2;MDM2 GO:0071363| cellular response to growth factor stimulus TRPV1;MDM2;CAT;OPRD1 GO:0042220| response to cocaine MDM2;SMPD1;OPRM1;CNR1 GO:0045892| negative regulation of transcription, DNA-dependent MDM2;PPARG GO:0010977| negative regulation of neuron projection development TRPV4;MDM2 GO:0010628| positive regulation of gene expression TRPV4;MDM2 GO:0007507| heart development MDM2;PPARG GO:0002027| regulation of heart rate CACNA1G;MDM2 GO:0071312| cellular response to alkaloid TRPV1;MDM2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;PTGS2;GPX1 GO:0010629| negative regulation of gene expression MDM2;OPRD1 GO:0016032| viral reproduction MDM2;VDAC1;HTR2A GO:0009636| response to toxin CYP1B1;CYP1A1;MDM2;CAT;GPX1 GO:0070301| cellular response to hydrogen peroxide MDM2;CYP1B1 20477:[DB14011 DB07430] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways GO:0006954| inflammatory response MAPKAPK2;TRPV1;IDO1;ALOX15;ALOX5;PTGS1;CNR2;PTGS2 GO:0034097| response to cytokine stimulus MAPKAPK2;AANAT;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;MAPKAPK2;CYP1A1;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;MAPKAPK2;ALOX5 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;MAPKAPK2 20478:[DB14011 DB03639] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPV1;TRPM8;CAT;DHPS GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;DHPS GO:0042593| glucose homeostasis CNR1;DHPS;PPARG;TRPV4 20479:[DB14011 DB07563] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07563|1-{7-cyclohexyl-6-[4-(4-methylpiperazin-1-yl)benzyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine CTSK common genes common pathways GO:1903146| CTSK;VDAC1 GO:0045453| bone resorption CTSK;GPR55 20480:[DB14011 DB11133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes PPARG;ALOX5;PTGS2 common pathways GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0061614| PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0019370| leukotriene biosynthetic process ALOX5;PLA2G1B GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ALOX5;PTGS1;PTGS2;CNR2 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0050872| white fat cell differentiation PPARG GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0006357| regulation of transcription from RNA polymerase II promoter SREBF1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARA;PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARA;PPARG;SREBF1 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRD1;OPRM1;PTGS2;CNR2;CNR1;HTR2A GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0048469| cell maturation PPARG GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process SREBF1;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9;NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PPARA GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARA;PPARG GO:0045165| cell fate commitment PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound SREBF1;TRPA1;PPARG;CYP1A1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0032868| response to insulin stimulus CAT;AANAT;PPARA;TRPV4 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0055088| lipid homeostasis PPARG GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0010887| negative regulation of cholesterol storage PPARG;PPARA GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0010226| response to lithium ion PTGS2 GO:0019216| regulation of lipid metabolic process HMGCR;PPARA;CNR1;CYP1A1;PPARG GO:0007566| embryo implantation SOD1;PTGS2 GO:0043434| response to peptide hormone stimulus TRPV1;SREBF1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:1905461| PPARG GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0032869| cellular response to insulin stimulus SREBF1;PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0050796| regulation of insulin secretion SREBF1;CNR1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2;SREBF1 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0032094| response to food CYP1A1;SREBF1;OPRM1 GO:0006631| fatty acid metabolic process ALOX15;PPARA;PTGS2;PTGS1 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;SREBF1;PPARG GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;SREBF1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0045444| fat cell differentiation SREBF1;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARA;PPARG;SREBF1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A1;CYP2C9;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0030224| monocyte differentiation PPARG GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071455| cellular response to hyperoxia PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0009750| response to fructose stimulus PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA GO:0030308| negative regulation of cell growth PPARG GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0042060| wound healing ALOX15;OPRM1;PPARA GO:0008203| cholesterol metabolic process SREBF1;HMGCR;CAT GO:0007612| learning PTGS2;VDAC1 GO:0007623| circadian rhythm SREBF1;AANAT GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0071284| cellular response to lead ion PTGS2 GO:0030324| lung development CYP1A2;SREBF1 GO:0032526| response to retinoic acid SREBF1;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;PLA2G1B;SREBF1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 GO:0043312| neutrophil degranulation CAT;ALOX5 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;SREBF1;TRPV4;TRPV1;PPARG GO:0051591| response to cAMP SREBF1;AANAT GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0045540| regulation of cholesterol biosynthetic process HMGCR;SREBF1 GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0034612| response to tumor necrosis factor PTGS2 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;PPARA GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:2001300| ALOX5 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0008202| steroid metabolic process CYP1B1;SREBF1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:1902219| PTGS2 GO:0015909| long-chain fatty acid transport PPARG GO:0007568| aging CYP1A1;SREBF1;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT GO:1903146| SREBF1;VDAC1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0098869| GSR;PTGS2;CAT;PTGS1;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0043388| positive regulation of DNA binding PPARG GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0033993| response to lipid PPARG;SREBF1 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG 20481:[DB14011 DB02376] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02376|D-gluconhydroximo-1,5-lactam LCT common genes common pathways GO:0008152| metabolic process LCT;SMPD1;ACAT1 20482:[DB14011 DB01325] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways GO:0035725| sodium ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;SLC12A3 GO:1902476| GLRB;GLRA1;SLC12A1;SLC12A3;GLRA3;SLC12A2 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0006821| chloride transport GLRA3;SLC12A2;GLRB;GLRA1 GO:0006811| ion transport TRPV3;CACNA1H;SLC12A2;GLRA3;SLC12A3;TRPV2;CHRNA7;SLC12A1;CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 GO:0001822| kidney development CA2;CAT GO:0006810| transport SLC12A2;TRPV2;SLC12A3;SLC12A1;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0007568| aging CYP1A1;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;SLC12A2;HMGCR;CAT GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;GLRA3;SLC12A1;CHRNA7 GO:0055085| transmembrane transport SLC12A3;TRPV2;SLC12A1;TRPV3;CACNA1H;SLC12A2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;SOD1;PTGS2;CYP1A2 20483:[DB14011 DB07845] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07845|2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;MAPK8;GPX1 GO:0051247| positive regulation of protein metabolic process MAPK8;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;MAPK8 GO:0048511| rhythmic process PPARG;AANAT;MAPK8 GO:0043065| positive regulation of apoptotic process MAPK8;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0071260| cellular response to mechanical stimulus PTGS2;MAPK8 GO:0042752| regulation of circadian rhythm MAPK8;PPARG GO:0071276| cellular response to cadmium ion MAPK8;SOD1;CYP1A2 GO:0009411| response to UV MAPK8;CAT 20484:[DB14011 DB04537] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways GO:0010628| positive regulation of gene expression WARS;TRPV4 GO:0008285| negative regulation of cell proliferation WARS;PPARG;CYP1B1;OPRM1;PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1;WARS 20485:[DB14011 DB13934] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13934|Ligandrol AR common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter AR;PPARG;TRPV4;TRPV1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0007283| spermatogenesis SOD1;CNR1;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;TRPV2;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;AR GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;AR;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 20486:[DB14011 DB04985] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04985|Tigapotide RPSA common genes common pathways GO:0046718| entry of virus into host cell HTR2A;RPSA GO:0016032| viral reproduction HTR2A;RPSA;VDAC1 GO:0007155| cell adhesion RPSA;CYP1B1 20487:[DB14011 DB01162] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01162|Terazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ABCB1 common genes common pathways GO:0006915| apoptotic process ADRA1A;VDAC1;GPX1 GO:0055085| transmembrane transport TRPM8;ABCG2;KCNH6;CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G;KCNH7;TRPV2;TRPV3;KCNH2;CACNA1H GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ADRA1A;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;CHRNA7 GO:0007202| activation of phospholipase C activity ADRA1A;HTR2A;GPR55 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;ADRA1B;GPR18;PPARG;ADRA1D;ADRA1A GO:0007568| aging CAT;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;ADRA1A;CYP1A1 GO:0006810| transport TRPV2;ABCC1;ABCB1;CACNA1I;TRPV1;ABCG2 GO:0042391| regulation of membrane potential KCNH7;CACNA1G;GLRA1;KCNH6;GLRB;CACNA1H;KCNH2 GO:0042593| glucose homeostasis TRPV4;PPARG;ADRA1B;CNR1 GO:0042493| response to drug ABCG2;ABCB1;ADRA1A;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ADRA1A;ADRA1D;ADRA1B;HTR2A;OPRD1;OPRM1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;ADRA1D GO:0006811| ion transport CACNA1G;KCNH7;GLRA1;TRPA1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;KCNH6;TRPM8;KCNH2;CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0008283| cell proliferation CYP1A1;ADRA1D;ADRA1B;GPX1;HTR1A GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;PTGS2;ADRA1B GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;ADRA1A;PPARG GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0007204| elevation of cytosolic calcium ion concentration ADRA1D;ADRA1A;TRPV4;TRPV1;HTR2A;OPRM1;ADRA1B GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;ADRA1B;ADRA1D;ADRA1A GO:0034765| regulation of ion transmembrane transport CACNA1G;KCNH7;CACNA1I;KCNH6;KCNH2;CACNA1H GO:0006939| smooth muscle contraction HTR2A;ADRA1A GO:0007165| signal transduction PLA2G1B;CACNA1I;ADRA1A;GPR18;PPARG;SMPD1;ADRA1D;CHRNA7;ADRA1B;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0009725| response to hormone stimulus ACAT1;ADRA1A GO:0086010| CACNA1G;CACNA1I;CACNA1H;KCNH2 GO:0086091| KCNH2;KCNH6;CACNA1G GO:0035556| intracellular signal transduction ADRA1A;PLA2G1B;ADRA1B GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRA1B;ADRA1D 20488:[DB14011 DB05141] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05141|LY2181308 BIRC5 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1;BIRC5 GO:0006351| transcription, DNA-dependent PPARG;BIRC5 GO:0045892| negative regulation of transcription, DNA-dependent BIRC5;PPARG GO:0006915| apoptotic process VDAC1;BIRC5;GPX1 GO:0007605| sensory perception of sound GPX1;BIRC5;SOD1 GO:0006355| regulation of transcription, DNA-dependent BIRC5;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;BIRC5;CHRNA7 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;BIRC5;CAT 20489:[DB14011 DB00058] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;ELANE GO:0009411| response to UV ELANE;CAT GO:0006874| cellular calcium ion homeostasis TRPV4;ELANE;TRPM8;CHRNA7;HTR2A;GPR12 GO:0043406| positive regulation of MAP kinase activity HTR2A;ELANE GO:0050778| positive regulation of immune response ELANE;PLA2G1B GO:0032496| response to lipopolysaccharide ELANE;IDO1;CYP1A1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0043312| neutrophil degranulation ELANE;ALOX5;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;ELANE;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation ELANE;HMGCR;PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;ELANE 20490:[DB14011 DB04398] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;SLCO2B1;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G GO:0050796| regulation of insulin secretion SLC16A1;CNR1 GO:0006629| lipid metabolic process SLC16A1;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0055085| transmembrane transport SLCO2A1;ABCC1;CACNA1G;SLC16A3;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;SLCO2B1;TRPM8;ABCG2;TRPV3;SLC16A10;CACNA1H;SLC16A7;TRPV2;SLC16A1 GO:0042593| glucose homeostasis CNR1;SLC16A1;PPARG;TRPV4 GO:0032094| response to food OPRM1;SLC16A1;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;SLC16A1 20491:[DB14011 DB06883] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06883|1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea SRC common genes common pathways GO:0008283| cell proliferation GPX1;SRC;HTR1A;CYP1A1 GO:0045453| bone resorption SRC;GPR55 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;SRC;CHRNA7 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC GO:0016032| viral reproduction VDAC1;HTR2A;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;SRC;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;SRC;GPX1 GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0051974| negative regulation of telomerase activity PPARG;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;SRC;CHRNA7 GO:0002376| immune system process SRC;IDO1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;SRC;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0016236| macroautophagy VDAC1;SRC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0009615| response to virus CYP1A1;SRC GO:0009612| response to mechanical stimulus SRC;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process CAT;GPX1;SRC;SOD1;PTGS2;HMGCR GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0042127| regulation of cell proliferation PTGS2;SRC;PTGS1 20492:[DB14011 DB00100] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00100|Coagulation Factor IX (Recombinant) F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0007623| circadian rhythm F7;AANAT GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;F2 GO:0002576| platelet degranulation SOD1;F8 GO:0055114| oxidation-reduction process F8;CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F7;F10 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;F2;PPARG;GPR18 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;F7 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0007568| aging CYP1A1;LRP1;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0031100| organ regeneration F7;PPARG GO:0043277| apoptotic cell clearance LRP1;ALOX15 GO:0010977| negative regulation of neuron projection development TRPV4;LRP1 GO:0001666| response to hypoxia F7;CYP1A1;CAT;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0042953| lipoprotein transport PPARG;LRP1 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9;LRP1 GO:0031667| response to nutrient levels SOD1;F7 GO:0043524| negative regulation of neuron apoptosis SOD1;LRP1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0009725| response to hormone stimulus ACAT1;F7 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1;F7 GO:0008283| cell proliferation LRP1;CYP1A1;GPX1;HTR1A GO:0001523| retinoid metabolic process LRP1;NAPEPLD GO:0061844| F2;PLA2G1B GO:0043627| response to estrogen stimulus F7;PPARG 20493:[DB14011 DB05099] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05099|Ancrod FGA common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;FGA;ALOX15 GO:0050714| positive regulation of protein secretion PLA2G1B;FGA GO:0002376| immune system process FGA;IDO1 GO:0002576| platelet degranulation FGA;SOD1 GO:0045087| innate immune response PPARG;FGA GO:1902042| FGA;GPX1 GO:0045907| positive regulation of vasoconstriction FGA;PTGS2;HTR2A GO:0007165| signal transduction CACNA1I;PLA2G1B;FGA;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0034116| positive regulation of heterotypic cell-cell adhesion FGA;ALOX15 GO:0051592| response to calcium ion FGA;AANAT 20494:[DB14011 DB07031] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07031|3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid RARG common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;RARG GO:0043401| steroid hormone mediated signaling pathway RARG;PPARG GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;RARG;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;RARG GO:0043010| camera-type eye development RARG;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent RARG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter RARG;PPARG GO:0032526| response to retinoic acid PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARG;TRPV4;TRPV1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;RARG;PTGS2;HMGCR;SOD1 GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;RARG GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;RARG GO:0010628| positive regulation of gene expression TRPV4;RARG GO:0010468| regulation of gene expression CYP1A2;RARG 20495:[DB14011 DB11359] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11359|Guaiacol ALB common genes common pathways GO:0098869| GSR;ALB;GPX1;PTGS1;CAT;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0002576| platelet degranulation SOD1;ALB GO:0001895| retina homeostasis ALB;SOD1 20496:[DB14011 DB07161] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;JAK2;PPARG;PTGS2;SOD1;CNR1 GO:0050727| regulation of inflammatory response JAK2;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;JAK2 GO:0043524| negative regulation of neuron apoptosis JAK2;SOD1 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;JAK2 GO:0050729| positive regulation of inflammatory response TRPV4;JAK2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;JAK2;OPRM1;HTR2A GO:0010811| positive regulation of cell-substrate adhesion JAK2;ALOX15 GO:0007165| signal transduction CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;JAK2;CACNA1I;PLA2G1B GO:0006919| activation of caspase activity JAK2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;JAK2;PPARG;CYP1B1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;IDO1;CYP1A1;JAK2 GO:0042127| regulation of cell proliferation JAK2;PTGS2;PTGS1 GO:0008284| positive regulation of cell proliferation JAK2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0046677| response to antibiotic CYP1A1;JAK2;SOD1 GO:0035722| interleukin-12-mediated signaling pathway JAK2;SOD1 GO:0045087| innate immune response JAK2;PPARG GO:0033194| response to hydroperoxide GPX1;JAK2 GO:0007186| G-protein coupled receptor signaling pathway JAK2;PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade JAK2;CAT GO:0002376| immune system process IDO1;JAK2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;JAK2;OPRM1;PTGS2 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2;JAK2 GO:0043388| positive regulation of DNA binding PPARG;JAK2 GO:0034612| response to tumor necrosis factor JAK2;PTGS2 GO:0006915| apoptotic process VDAC1;JAK2;GPX1 20497:[DB14011 DB03777] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03777|Rbt205 Inhibitor PIM1;PDPK1;PRKCI common genes common pathways GO:0035556| intracellular signal transduction PLA2G1B;PDPK1;PRKCI GO:0006351| transcription, DNA-dependent PDPK1;PPARG GO:0010976| positive regulation of neuron projection development PRKCI;CNR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;PRKCI;CAT GO:0043524| negative regulation of neuron apoptosis PDPK1;SOD1;PRKCI GO:0043434| response to peptide hormone stimulus PRKCI;TRPV1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PDPK1;PRKCI GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;PIM1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;PIM1;SOD1;PRKCI;GPX1;CAT GO:0007015| actin filament organization PRKCI;TRPV4;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1 GO:0006915| apoptotic process PIM1;GPX1;VDAC1 GO:0045766| positive regulation of angiogenesis CHRNA7;PDPK1;CYP1B1 20498:[DB14011 DB03677] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways GO:0072593| reactive oxygen species metabolic process SOD1;EPHX2 GO:0009636| response to toxin CAT;GPX1;EPHX2;CYP1B1;CYP1A1 GO:0008217| regulation of blood pressure EPHX2;SOD1;PTGS2;PTGS1;PPARG GO:0006629| lipid metabolic process PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;CYP2C9;PPARG;PTGS1;NAAA;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;EPHX2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;EPHX2;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9 GO:0008152| metabolic process EPHX2;ACAT1;SMPD1 GO:0006954| inflammatory response EPHX2;CNR2;PTGS2;PTGS1;ALOX5;IDO1;ALOX15;TRPV1 GO:0017144| drug metabolic process EPHX2;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;HTR2A;GPR12;EPHX2;CHRNA7 GO:0010628| positive regulation of gene expression TRPV4;EPHX2 GO:0019373| epoxygenase P450 pathway CYP1A2;EPHX2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 20499:[DB14011 DB08009] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways GO:0035556| intracellular signal transduction CAMK1G;PLA2G1B GO:0008152| metabolic process SMPD1;CAMK1G;ACAT1 20500:[DB14011 DB03886] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03886|Biopterin SPR;PTS;DHFR common genes common pathways GO:0006809| nitric oxide biosynthetic process SPR;CYP1B1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SPR;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;DHFR;CYP2C9;CYP1A1 20501:[DB14011 DB02530] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways GO:0007268| synaptic transmission GLRA1;CACNA1G;GABBR2;VDAC1;GLRB;HTR2A;GLRA3;OPRM1;OPRD1 GO:0007194| negative regulation of adenylate cyclase activity GABBR2;OPRM1;GABBR1 GO:0006811| ion transport CHRNA7;TRPV2;SLC36A1;GLRA3;TRPV3;CACNA1H;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPA1;GLRA1;CACNA1G GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GABBR1;GABBR2;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;GABBR1 GO:0007611| learning or memory GATM;CNR1;CHRNA7 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;SLC36A1;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;ABCG2;TRPM8 GO:0007186| G-protein coupled receptor signaling pathway GABBR2;PPARG;GPR18;GPR55;HTR1A;GPR12;CNR1;HTR2A;GABBR1;OPRM1;CNR2;OPRD1 20502:[DB14011 DB05879] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05879|AME-527 TNF common genes common pathways GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1;PTGS2 GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15 GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0050796| regulation of insulin secretion CNR1;TNF GO:0006919| activation of caspase activity PPARG;TNF GO:0043065| positive regulation of apoptotic process SMPD1;TNF;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0000060| protein import into nucleus, translocation OPRD1;TNF GO:0031622| positive regulation of fever generation TNF;CNR1;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNF;PLA2G1B GO:0006954| inflammatory response TNF;IDO1;ALOX15;TRPV1;PTGS2;CNR2;ALOX5;PTGS1 GO:0006955| immune response TNF;CNR2;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNF GO:0010629| negative regulation of gene expression OPRD1;TNF GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;TRPV1;OPRM1;PTGS2 GO:0010628| positive regulation of gene expression TNF;TRPV4 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0010033| response to organic substance TRPA1;TNF;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0000187| activation of MAPK activity PLA2G1B;TNF;CHRNA7;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;PLA2G1B GO:0009615| response to virus CYP1A1;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;TNF GO:0042127| regulation of cell proliferation TNF;PTGS2;PTGS1 GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0046330| positive regulation of JNK cascade TRPV4;TNF GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0050830| defense response to Gram-positive bacterium TNF;PLA2G1B GO:0071407| cellular response to organic cyclic compound CYP1A1;TNF;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;PPARG 20503:[DB14011 DB11186] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes OPRM1 common pathways GO:0043278| response to morphine OPRK1;CNR1;OPRM1 GO:0032100| positive regulation of appetite OPRM1 GO:0032094| response to food OPRM1;CYP1A1 GO:0007191| activation of adenylate cyclase activity by dopamine receptor signaling pathway OPRM1 GO:0007626| locomotory behavior OPRK1;OPRM1;SOD1 GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;GLRA1;GLRB;OPRK1 GO:0070207| protein homotrimerization TRPM8;SIGMAR1 GO:0070848| response to growth factor stimulus OPRM1 GO:0043523| regulation of neuron apoptosis SIGMAR1;GPX1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0033554| cellular response to stress OPRM1 GO:0042060| wound healing ALOX15;OPRM1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;OPRK1 GO:0061358| negative regulation of Wnt protein secretion OPRM1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0042220| response to cocaine SMPD1;OPRK1;OPRM1;CNR1 GO:0050769| positive regulation of neurogenesis OPRM1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0055085| transmembrane transport TRPV2;CACNA1H;KCNH2;TRPV3;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;TRPA1;CACNA1G;ABCC1 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;GLRB;GLRA1;CACNA1G GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway OPRK1;PPARG;GPR18;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0038003| opioid receptor signaling pathway OPRM1;SIGMAR1;OPRD1;OPRK1 GO:0006955| immune response CNR2;OPRD1;OPRK1 GO:0086010| CACNA1H;KCNH2;CACNA1G;CACNA1I GO:0007600| sensory perception TRPV2;OPRM1;OPRK1 GO:0043951| negative regulation of cAMP-mediated signaling OPRM1 GO:0048149| behavioral response to ethanol OPRM1 GO:0007268| synaptic transmission OPRK1;VDAC1;GLRB;GLRA1;CACNA1G;GLRA3;HTR2A;OPRM1;OPRD1 GO:0048148| behavioral response to cocaine HTR2A;OPRK1 GO:0009314| response to radiation CAT;PTGS2;OPRM1;OPRK1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1 GO:0007399| nervous system development SIGMAR1;SMPD1;GLRB GO:0086091| KCNH2;CACNA1G GO:0007194| negative regulation of adenylate cyclase activity OPRM1 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1;OPRK1;TRPV1;TRPA1 GO:0045471| response to ethanol OPRK1;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0030818| negative regulation of cAMP biosynthetic process OPRM1 GO:0043627| response to estrogen stimulus PPARG;OPRK1 GO:0051930| regulation of sensory perception of pain OPRK1;OPRD1;OPRM1 GO:0006811| ion transport KCNH2;CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8 GO:0042755| eating behavior OPRK1;OPRD1;OPRM1 GO:0002438| acute inflammatory response to antigenic stimulus OPRM1 GO:0032868| response to insulin stimulus AANAT;CAT;OPRK1;TRPV4 GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1 GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;CACNA1H;KCNH2 GO:0044849| OPRM1;OPRK1 GO:0050951| sensory perception of temperature stimulus OPRK1;TRPM8 GO:0045019| negative regulation of nitric oxide biosynthetic process OPRM1 GO:0007610| behavior HTR1A;HTR2A;OPRK1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;OPRK1;PLA2G1B;CACNA1I;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;OPRK1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;HTR2A;OPRM1 GO:0071315| cellular response to morphine OPRM1 20504:[DB14011 DB13877] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13877|Iniparib PARP1 common genes common pathways GO:0071294| cellular response to zinc ion GLRA1;PARP1 GO:0006351| transcription, DNA-dependent PARP1;PPARG GO:0032869| cellular response to insulin stimulus PARP1;PPARG;PLA2G1B GO:0010332| response to gamma radiation GPX1;PARP1 GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0034599| cellular response to oxidative stress SOD1;PARP1;CAT;GPX1;GSR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PARP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PARP1 GO:0006915| apoptotic process VDAC1;GPX1;PARP1 20505:[DB14011 DB04476] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04476|Trencam-3,2-Hopo LCN2 common genes common pathways GO:0002376| immune system process LCN2;IDO1 GO:0006915| apoptotic process VDAC1;LCN2;GPX1 GO:0045087| innate immune response PPARG;LCN2 GO:0043312| neutrophil degranulation ALOX5;LCN2;CAT GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;LCN2;CHRNA7;CACNA1G;TRPA1;GLRA1;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;LCN2 20506:[DB14011 DB08325] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways GO:0043277| apoptotic cell clearance MERTK;ALOX15 GO:0007283| spermatogenesis CNR1;SOD1;MERTK GO:0007166| cell surface receptor linked signaling pathway MERTK;TRPA1;TRPV1 20507:[DB14011 DB07449] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0045087| innate immune response PPARG;PADI4 GO:0006355| regulation of transcription, DNA-dependent PPARG;PADI4 GO:0002376| immune system process IDO1;PADI4 GO:0006351| transcription, DNA-dependent PADI4;PPARG 20508:[DB14011 DB01279] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01279|Galsulfase PLIN3 common genes common pathways 20509:[DB14011 DB07005] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07005|D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide F2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;GPR18;PPARG;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 20510:[DB14011 DB07933] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07933|Erteberel ESR2;ESR1 common genes common pathways GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;TRPV4;TRPV1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;ESR2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;ESR1;HTR2A GO:0007165| signal transduction OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;ESR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;ESR2 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 20511:[DB14011 DB07283] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07283|9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid FABP4 common genes common pathways GO:0071356| cellular response to tumor necrosis factor TRPV1;FABP4 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;FABP4 GO:0050872| white fat cell differentiation PPARG;FABP4 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0050729| positive regulation of inflammatory response TRPV4;FABP4 20512:[DB14011 DB00284] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways GO:0008152| metabolic process SI;SMPD1;MGAM;ACAT1;AMY2A;GAA GO:0050884| neuromuscular process controlling posture GLRA1;GAA GO:0007626| locomotory behavior OPRM1;SOD1;GAA GO:0043312| neutrophil degranulation CAT;MGAM;ALOX5;GAA GO:0046716| muscle cell homeostasis SOD1;GAA 20513:[DB14011 DB01401] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0019233| sensory perception of pain CNR1;HTR2A;OPRD1;OPRM1;PTGS2;CNR2;TRPV1;TRPA1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;CNR2;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;CYP1A1;PPARG;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CYP1A1 GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0098869| GSR;PTGS2;GPX1;PTGS1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 20514:[DB14011 DB08739] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08739|2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dione PREP common genes common pathways 20515:[DB14011 DB09085] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09085|Tetracaine RYR1;RYR2 common genes common pathways GO:0051209| release of sequestered calcium ion into cytosol RYR2;TRPV1;TRPA1;RYR1;HTR2A GO:0006874| cellular calcium ion homeostasis TRPM8;RYR2;TRPV4;HTR2A;GPR12;CHRNA7;RYR1 GO:0006936| muscle contraction GLRA1;CACNA1H;RYR1 GO:0055085| transmembrane transport TRPV3;CACNA1H;RYR1;TRPV2;ABCC1;CACNA1G;TRPA1;RYR2;TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2 GO:0034220| ion transmembrane transport RYR1;CHRNA7;GLRA3;RYR2;GLRB;TRPV1;TRPA1;GLRA1 GO:0031000| response to caffeine RYR1;RYR2;PPARG GO:0048741| skeletal muscle fiber development GPX1;RYR1 GO:0001666| response to hypoxia RYR1;CHRNA7;CAT;CYP1A1;RYR2 GO:0070588| calcium ion transmembrane transport TRPV3;OPRM1;CACNA1H;RYR1;TRPV2;CHRNA7;CACNA1G;TRPA1;RYR2;TRPV1;CACNA1I;TRPV4;TRPM8 GO:0006811| ion transport TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;RYR2;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;RYR1;GLRA3;CACNA1H;TRPV3 GO:0071277| cellular response to calcium ion RYR1;ALOX15 GO:0002027| regulation of heart rate CACNA1G;RYR2 GO:0006816| calcium ion transport TRPV2;RYR1;CHRNA7;CACNA1H;TRPV3;TRPV1;TRPV4;CACNA1I;RYR2;TRPM8;CACNA1G;TRPA1 GO:0051289| protein homotetramerization TRPV1;TRPM8;TRPA1;CRYZ;RYR1;CAT 20516:[DB14011 DB06560] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06560|Pascolizumab IL4 common genes common pathways GO:0045892| negative regulation of transcription, DNA-dependent PPARG;IL4 GO:0045671| negative regulation of osteoclast differentiation IL4;GPR55 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;IL4 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;IL4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;IL4 GO:0008203| cholesterol metabolic process CAT;HMGCR;IL4 GO:0006955| immune response IL4;OPRD1;CNR2 20517:[DB14011 DB05889] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0007155| cell adhesion CD22;CYP1B1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;ABCB1;CACNA1I;TRPV4;TRPM8;ABCG2 GO:0006810| transport ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2;TRPV2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 20518:[DB14011 DB05367] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05367|Actelion-1 EDNRA common genes common pathways GO:0014824| artery smooth muscle contraction EDNRA;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG;EDNRA GO:0001666| response to hypoxia EDNRA;CYP1A1;CAT;CHRNA7 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EDNRA GO:0015758| glucose transport PLA2G1B;EDNRA GO:0042310| vasoconstriction HTR1A;EDNRA GO:0007507| heart development EDNRA;PPARG GO:0006939| smooth muscle contraction EDNRA;HTR2A GO:0007165| signal transduction GPR18;EDNRA;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;EDNRA;OPRM1;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDNRA;OPRD1;OPRM1 GO:0008217| regulation of blood pressure EDNRA;PPARG;PTGS1;PTGS2;SOD1 GO:0008283| cell proliferation HTR1A;GPX1;EDNRA;CYP1A1 20519:[DB14011 DB01004] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01004|Ganciclovir SLC22A1;SLC22A6;SLC22A8;SLC22A7;SLC47A1;SLC47A2 common genes common pathways GO:0006811| ion transport TRPV2;SLC22A7;CHRNA7;CACNA1H;TRPV3;SLC22A8;GLRA3;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8;CACNA1G;SLC22A1;GLRA1;TRPA1 GO:0009636| response to toxin SLC22A8;CAT;GPX1;CYP1A1;CYP1B1 GO:0006855| drug transmembrane transport ABCC1;SLC22A1;ABCG2;SLC47A2;SLC47A1 GO:0006812| cation transport SLC22A1;TRPM8 GO:0098656| SLC22A7;SLC22A8;VDAC1;SLC22A6 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6;SLC22A1 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0055085| transmembrane transport SLC22A8;TRPV3;CACNA1H;SLC22A7;SLC47A2;SLC47A1;TRPV2;TRPA1;ABCC1;SLC22A1;CACNA1G;SLC22A6;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1 20520:[DB14011 DB08499] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways GO:0035556| intracellular signal transduction CASP3;PLA2G1B GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;CASP3;GPX1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;CASP3;PTGS2;SOD1;CNR1 GO:0045165| cell fate commitment PPARG;CASP3 GO:0007507| heart development CASP3;PPARG GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;CASP3;ACAT1;AANAT;TRPA1;PPARG;CYP1A1 GO:0009411| response to UV CAT;CASP3 GO:0006919| activation of caspase activity PPARG;CASP3 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;CASP3 GO:0046677| response to antibiotic CYP1A1;SOD1;CASP3 GO:0007611| learning or memory CNR1;CHRNA7;CASP3 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CASP3;CNR1;PTGS2;CNR2;OPRM1;CYP1A2 GO:0042060| wound healing ALOX15;OPRM1;CASP3 GO:0035094| response to nicotine CNR1;CASP3;CHRNA7 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;CASP3 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CASP3;CAT GO:0007605| sensory perception of sound SOD1;GPX1;CASP3 GO:0009611| response to wounding CASP3;GPX1;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CASP3;CAT GO:0001666| response to hypoxia CAT;CHRNA7;CASP3;CYP1A1 GO:0010033| response to organic substance CASP3;SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0043200| response to amino acid stimulus CASP3;GLRA3;GLRB GO:0006915| apoptotic process VDAC1;CASP3;GPX1 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 20521:[DB14011 DB01013] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes CYP3A4;CYP1A1 common pathways GO:0032502| developmental process CYP1A1 GO:1900087| CYP1A1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:0007165| signal transduction GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;NR3C1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0043010| camera-type eye development CYP1A1 GO:0009624| response to nematode CYP1A1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;AANAT;ACAT1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0001889| liver development CYP1A1;ACAT1 GO:0070988| demethylation CYP1A1 GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP1A2;CYP3A4 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0009692| ethylene metabolic process CYP1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0009635| response to herbicide CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0007568| aging CYP1A1;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CAT GO:0009611| response to wounding GPX1;CYP1A1 GO:0008202| steroid metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0010041| response to iron(III) ion CYP1A1 GO:0036378| CYP3A4 GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;TRPV1;TRPV4;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PLA2G1B;PPARG GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0042493| response to drug ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0032094| response to food CYP1A1;OPRM1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009308| amine metabolic process CYP1A1 20522:[DB14011 DB04369] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04369|1,3,2-Dioxaborolan-2-Ol PRSS3 common genes common pathways GO:0009235| cobalamin metabolic process PRSS3;ABCC1 GO:0043542| endothelial cell migration PRSS3;CYP1B1 GO:0043312| neutrophil degranulation CAT;ALOX5;PRSS3 20523:[DB14011 DB12020] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;IDO1;UGT1A1;CYP1A1 GO:0042594| response to starvation UGT1A1;PPARG;ACAT1 GO:0042493| response to drug CYP1A2;PTGS2;HTR2A;SOD1;CAT;UGT1A1;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C9;CYP1A1;UGT1A1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A4;UGT1A1;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0001889| liver development ACAT1;UGT1A1;CYP1A1 GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;CAT;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1;CYP1A1;CYP2C19;CYP2D6 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0008152| metabolic process SMPD1;UGT1A1;UGT1A4;ACAT1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0007584| response to nutrient UGT1A1;PPARG;HMGCR;CNR1 20524:[DB14011 DB07120] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07120|N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINE F2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 20525:[DB14011 DB06235] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes CYP1A2 common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0008152| metabolic process ACAT1;UGT2B7;SMPD1;UGT1A9 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;UGT1A9;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;NAAA;UGT2B7;GPX1;PTGS1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0008209| androgen metabolic process UGT2B7;CYP3A4 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1;UGT1A9 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;CYP1A1;PPARG;TRPA1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;CYP1A2;OPRM1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A9;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 20526:[DB14011 DB04971] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04971|Reglixane PPARA;PPARG common genes PPARG common pathways GO:0019216| regulation of lipid metabolic process PPARA;CNR1;HMGCR;PPARG;CYP1A1 GO:1905461| PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARA;PPARG GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG GO:0032868| response to insulin stimulus PPARA;AANAT;CAT;TRPV4 GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;PPARA GO:0006351| transcription, DNA-dependent PPARG;PPARA GO:0045776| negative regulation of blood pressure PPARA;CNR1 GO:0048469| cell maturation PPARG GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;PPARA;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARG;PPARA GO:0045165| cell fate commitment PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0061614| PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG;PPARA GO:0050872| white fat cell differentiation PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PPARG;GPR18 GO:0015909| long-chain fatty acid transport PPARG GO:0010468| regulation of gene expression PPARA;CYP1A2 GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG;PPARA GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG GO:0031100| organ regeneration PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0001666| response to hypoxia PPARA;CAT;CHRNA7;CYP1A1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;CYP1A2;PTGS2 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARA;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0030308| negative regulation of cell growth PPARG GO:0042060| wound healing ALOX15;PPARA;OPRM1 GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PLA2G1B;PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARA;TRPV4;TRPV1;PPARG GO:0006631| fatty acid metabolic process PTGS1;PPARA;PTGS2;ALOX15 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;PPARA GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARA GO:0030224| monocyte differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG;PPARA GO:0010742| macrophage derived foam cell differentiation PPARG GO:0050728| negative regulation of inflammatory response PPARA;CNR2 GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARA 20527:[DB14011 DB06919] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06919|D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway F2;PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 20528:[DB14011 DB00337] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes CYP3A4 common pathways GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4;MTOR GO:0007584| response to nutrient HMGCR;CNR1;MTOR;PPARG GO:0009791| post-embryonic development CYP1A2;MTOR GO:0007420| brain development ACAT1;MTOR GO:0007165| signal transduction MTOR;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CHRNA7 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0070588| calcium ion transmembrane transport CACNA1H;OPRM1;TRPV3;TRPV2;CHRNA7;CACNA1G;TRPA1;TRPV1;CACNA1I;TRPV4;FKBP1A;TRPM8 GO:0001934| positive regulation of protein phosphorylation CHRNA7;MTOR GO:0008209| androgen metabolic process CYP3A4 GO:0045859| regulation of protein kinase activity MTOR;SOD1 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0008542| visual learning HMGCR;MTOR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;MTOR GO:0043087| regulation of GTPase activity MTOR;SOD1 GO:0010976| positive regulation of neuron projection development MTOR;CNR1 GO:0010942| positive regulation of cell death MTOR;PTGS2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0042220| response to cocaine CNR1;OPRM1;MTOR;SMPD1 GO:0050769| positive regulation of neurogenesis MTOR;OPRM1 GO:0036378| CYP3A4 GO:0043200| response to amino acid stimulus GLRA3;GLRB;MTOR GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP1A1 GO:0031000| response to caffeine PPARG;FKBP1A GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;MTOR GO:1902991| CHRNA7;FKBP1A GO:0010628| positive regulation of gene expression MTOR;TRPV4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0071456| cellular response to hypoxia MTOR;SLC29A1;PTGS2;OPRD1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;FKBP1A;TRPA1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;MTOR GO:0006936| muscle contraction FKBP1A;GLRA1;CACNA1H GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0007569| cell aging MTOR;SOD1 GO:0043278| response to morphine CNR1;OPRM1;MTOR GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation MTOR;HMGCR;PTGS2 GO:0071230| cellular response to amino acid stimulus GLRA1;MTOR GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0030838| positive regulation of actin filament polymerization ALOX15;MTOR GO:0060135| maternal process involved in female pregnancy CNR1;MTOR GO:0042060| wound healing OPRM1;MTOR;ALOX15 20529:[DB14011 DB05092] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05092|CDP323 ITGA4 common genes common pathways GO:0071345| cellular response to cytokine stimulus ITGA4;TRPV1 GO:0007155| cell adhesion ITGA4;CYP1B1 20530:[DB14011 DB01340] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways GO:0007283| spermatogenesis CNR1;SOD1;ACE GO:0055085| transmembrane transport TRPA1;SLC15A1;ABCC1;CACNA1G;TRPM8;ABCG2;VDAC1;CACNA1I;ABCB1;TRPV4;TRPV1;SLC15A2;TRPV3;CACNA1H;TRPV2 GO:0006810| transport TRPV2;SLC15A2;TRPV1;ABCB1;CACNA1I;ABCG2;ABCC1;SLC15A1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0042493| response to drug ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0001822| kidney development ACE;CAT GO:0008217| regulation of blood pressure PPARG;ACE;PTGS1;SOD1;PTGS2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;SLC15A2;CACNA1H;TRPV3;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;SLC15A1;GLRA1;TRPA1;CACNA1G GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0060047| heart contraction GPX1;ACE;SOD1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 20531:[DB14011 DB01042] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;SLC22A3;TRPV2 GO:0006810| transport TRPV2;ABCC1;SLC7A5;ABCG2;CACNA1I;TRPV1 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;SLC22A3;CACNA1H;GLRA3;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0006855| drug transmembrane transport SLC22A3;ABCG2;ABCC1 GO:0007399| nervous system development GLRB;SLC7A5;SMPD1 20532:[DB14011 DB05297] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0007565| female pregnancy IDO1;BCL2 GO:0008631| induction of apoptosis by oxidative stress GPX1;BCL2;CYP1B1 GO:0043524| negative regulation of neuron apoptosis SOD1;BCL2 GO:0051924| regulation of calcium ion transport OPRD1;BCL2 GO:0030217| T cell differentiation BCL2;GPR18 GO:0001503| ossification ALOX15;BCL2 GO:0042542| response to hydrogen peroxide SOD1;BCL2;CAT;GPX1;TRPA1 GO:0009314| response to radiation BCL2;PTGS2;OPRM1;CAT GO:0051881| regulation of mitochondrial membrane potential SOD1;BCL2;OPRD1 GO:0009636| response to toxin CAT;GPX1;BCL2;CYP1B1;CYP1A1 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;BCL2 GO:0008283| cell proliferation GPX1;HTR1A;BCL2;CYP1A1 GO:0008285| negative regulation of cell proliferation BCL2;PTGS2;OPRM1;CYP1B1;PPARG GO:0001662| behavioral fear response HTR1A;BCL2;VDAC1 GO:0009791| post-embryonic development BCL2;CYP1A2 GO:0030336| negative regulation of cell migration CYP1B1;BCL2 GO:0072593| reactive oxygen species metabolic process BCL2;SOD1 GO:0051384| response to glucocorticoid stimulus BCL2;PTGS2 GO:0010332| response to gamma radiation BCL2;GPX1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;BCL2;PTGS2 GO:0007569| cell aging BCL2;SOD1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;BCL2;SOD1;HTR2A GO:0007015| actin filament organization TRPV4;PLA2G1B;BCL2 GO:0035094| response to nicotine CHRNA7;BCL2;CNR1 GO:0030308| negative regulation of cell growth BCL2;PPARG GO:0034097| response to cytokine stimulus PTGS2;BCL2;AANAT GO:0001822| kidney development CAT;BCL2 GO:0043066| negative regulation of apoptotic process HMGCR;BCL2;PTGS2;SOD1;GPX1;CAT GO:0008284| positive regulation of cell proliferation CHRNA7;BCL2;HMGCR;PTGS2;HTR2A;HTR1A GO:0006915| apoptotic process VDAC1;GPX1;BCL2 GO:0001541| ovarian follicle development SOD1;BCL2 GO:0055085| transmembrane transport CACNA1H;BCL2;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1 GO:0001657| ureteric bud development CAT;BCL2 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;BCL2;OPRD1 GO:0010468| regulation of gene expression CYP1A2;BCL2 GO:0043085| positive regulation of catalytic activity BCL2;SOD1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;BCL2 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;HTR2A;GPR12;BCL2 GO:0048538| thymus development SOD1;BCL2 20533:[DB14011 DB03738] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways GO:0015937| coenzyme A biosynthetic process ACAT1;PPCDC 20534:[DB14011 DB00009] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0051592| response to calcium ion AANAT;FGA GO:0001525| angiogenesis CYP1B1;SERPINE1;PTGS2 GO:0061045| negative regulation of wound healing HMGCR;SERPINE1 GO:0001934| positive regulation of protein phosphorylation PLAUR;CHRNA7 GO:0050729| positive regulation of inflammatory response TRPV4;SERPINE1 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;FGA GO:0007165| signal transduction FGA;PLAUR;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0045907| positive regulation of vasoconstriction FGA;HTR2A;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG;PLG GO:1902042| SERPINE1;GPX1;FGA GO:0030336| negative regulation of cell migration SERPINE1;CYP1B1 GO:0007623| circadian rhythm SERPINE1;AANAT GO:0043312| neutrophil degranulation PLAUR;ALOX5;CAT GO:0045087| innate immune response PPARG;FGA GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;PLAUR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;SERPINE1 GO:0002576| platelet degranulation SERPINE1;SOD1;FGA;PLG GO:0051702| interaction with symbiont PLG;GPX1 GO:0033629| negative regulation of cell adhesion mediated by integrin SERPINE1;CYP1B1 GO:0043388| positive regulation of DNA binding PLAUR;PPARG GO:0002376| immune system process IDO1;FGA GO:0045766| positive regulation of angiogenesis CYP1B1;SERPINE1;CHRNA7 GO:0050714| positive regulation of protein secretion FGA;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;FGA;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A 20535:[DB14011 DB08890] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08890|Linaclotide GUCY2C common genes common pathways GO:0009636| response to toxin CYP1B1;GUCY2C;CYP1A1;GPX1;CAT GO:0035556| intracellular signal transduction PLA2G1B;GUCY2C GO:0042127| regulation of cell proliferation GUCY2C;PTGS1;PTGS2 20536:[DB14011 DB08436] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08436|8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;HSP90AA1;TRPV1 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AA1 GO:0007165| signal transduction HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;HSP90AA1;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0009409| response to cold PPARG;HSP90AA1;TRPA1;TRPM8 GO:0009408| response to heat TRPV2;SOD1;TRPV3;TRPV1;HSP90AA1 20537:[DB14011 DB12364] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12364|Betrixaban F10;F2;ABCB1;KCNH2 common genes common pathways GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCB1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1 GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 GO:0008284| positive regulation of cell proliferation F2;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1;KCNH2;CACNA1H;TRPV3;TRPV2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0006810| transport ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1;TRPV2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;F2;GPR18;PPARG GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;GLRB;CACNA1G;GLRA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0086010| KCNH2;CACNA1H;CACNA1I;CACNA1G GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0086091| CACNA1G;KCNH2 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0006811| ion transport TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;KCNH2;GLRA3 GO:0061844| PLA2G1B;F2 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;KCNH2;CACNA1H 20538:[DB14011 DB11134] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11134|Cupric oxide ALB;CP common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CP;ALOX5;PTGS1;GPX1;CAT GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0098869| GPX1;PTGS1;CAT;PTGS2;ALB;GSR GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;CP GO:0001895| retina homeostasis SOD1;ALB GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;CP;TRPV2;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPM8 20539:[DB14011 DB07285] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways GO:0043388| positive regulation of DNA binding PPARG;MMP9 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;MMP9 GO:0043312| neutrophil degranulation MMP9;ALOX5;CAT GO:0007566| embryo implantation MMP9;PTGS2;SOD1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;MMP9 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;MMP9;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0001503| ossification ALOX15;MMP9 GO:0001934| positive regulation of protein phosphorylation MMP9;CHRNA7 20540:[DB14011 DB03390] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways GO:0051289| protein homotetramerization TRPM8;TRPV1;CRYZ;TRPA1;ACPP;CAT GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ACPP GO:0043312| neutrophil degranulation CAT;ALOX5;ACPP 20541:[DB14011 DB07502] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07502|4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol HSP90AA1 common genes common pathways GO:0009409| response to cold TRPA1;PPARG;HSP90AA1;TRPM8 GO:0009408| response to heat TRPV3;SOD1;TRPV2;HSP90AA1;TRPV1 GO:0007165| signal transduction PPARG;HSP90AA1;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0046677| response to antibiotic SOD1;CYP1A1;HSP90AA1 GO:0043312| neutrophil degranulation HSP90AA1;CAT;ALOX5 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;PTGS2;OPRM1 20542:[DB14011 DB07419] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07419|S-23 AR common genes common pathways GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;AR GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation HTR1A;GPX1;AR;CYP1A1 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;AR;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;AR;CAT GO:0006351| transcription, DNA-dependent AR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport AR;TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0006355| regulation of transcription, DNA-dependent PPARG;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation AR;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A 20543:[DB14011 DB07876] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07876|(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE PRKACA;PKIA;ROCK1 common genes common pathways GO:0006939| smooth muscle contraction ROCK1;HTR2A GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0007165| signal transduction ROCK1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0035556| intracellular signal transduction PLA2G1B;ROCK1 GO:0002027| regulation of heart rate CACNA1G;PRKACA GO:1902430| ROCK1;CHRNA7 GO:0043524| negative regulation of neuron apoptosis ROCK1;SOD1 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2;PRKACA GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;GPR18;PPARG;ROCK1 GO:0010628| positive regulation of gene expression TRPV4;ROCK1 GO:0006915| apoptotic process VDAC1;ROCK1;GPX1 GO:0043312| neutrophil degranulation ROCK1;ALOX5;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;PKIA;TRPV4 GO:0071333| cellular response to glucose stimulus SLC29A1;PRKACA GO:0016525| negative regulation of angiogenesis ROCK1;PPARG 20544:[DB14011 DB04689] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes PPARG common pathways GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;GPX1;NAAA;PTGS1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;ACAT1;AANAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0015909| long-chain fatty acid transport PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG 20545:[DB14011 DB04577] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways GO:0001662| behavioral fear response HTR1A;VDAC1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;DPP4 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DPP4 20546:[DB14011 DB04099] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04099|Deamido-Nad+ nadE;NMNAT1;nadD;NMNAT3;nadE;nadE common genes common pathways GO:0009611| response to wounding NMNAT1;GPX1;NMNAT3;CYP1A1 20547:[DB14011 DB07069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways GO:0019441| tryptophan catabolic process to kynurenine IDO1;KYNU GO:0006569| tryptophan catabolic process IDO1;KYNU 20548:[DB14011 DB07728] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0000187| activation of MAPK activity PLA2G1B;MAPKAPK2;MAPKAPK3;CHRNA7;SOD1 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15;MAPKAPK2 GO:0034097| response to cytokine stimulus AANAT;PTGS2;MAPKAPK2;MAPKAPK3 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;IDO1;MAPKAPK2;CYP1A1;MAPKAPK3 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;MAPKAPK3 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;MAPKAPK2;PTGS1;ALOX5;PTGS2;CNR2 GO:0007166| cell surface receptor linked signaling pathway MAPKAPK3;TRPA1;TRPV1 20549:[DB14011 DB00509] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0009409| response to cold TRPM8;THRA;PPARG;TRPA1 GO:0001503| ossification ALOX15;THRA GO:0007399| nervous system development SLC7A5;GLRB;SMPD1 GO:0008016| regulation of heart contraction THRA;THRB;CACNA1H GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;PPARG;THRA GO:0043401| steroid hormone mediated signaling pathway THRA;PPARG;THRB GO:0006351| transcription, DNA-dependent THRB;THRA;PPARG GO:0006811| ion transport SLCO1B1;GLRA3;TRPV3;CACNA1H;CHRNA7;SLCO4A1;TRPV2;TRPA1;GLRA1;SLCO1C1;CACNA1G;TRPM8;SLCO4C1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;PPARG;PLA2G1B;THRB GO:0043312| neutrophil degranulation CAT;ALOX5;SLCO4C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;THRB;TRPV4 GO:0007611| learning or memory CNR1;CHRNA7;THRA GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;THRA;THRB GO:0006355| regulation of transcription, DNA-dependent THRB;PPARG;THRA GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;TPO GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR;TPO GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;TPO GO:0007605| sensory perception of sound SOD1;GPX1;THRB GO:0006810| transport ABCG2;SLC7A5;CACNA1I;TRPV1;ABCC1;TRPV2 GO:0007283| spermatogenesis SOD1;CNR1;SLCO4C1 GO:0045892| negative regulation of transcription, DNA-dependent THRA;PPARG;THRB GO:0042446| hormone biosynthetic process CYP17A1;TPO GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;TPO GO:0055085| transmembrane transport SLCO1B1;TRPV3;CACNA1H;SLCO4A1;TRPV2;TRPA1;SLCO1C1;ABCC1;CACNA1G;TRPM8;SLCO4C1;ABCG2;TRPV1;VDAC1;TRPV4;CACNA1I 20550:[DB14011 DB11118] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways GO:0051260| protein homooligomerization ACAT1;GLRA3;GLUL;GLRA1 GO:0051591| response to cAMP AANAT;CPS1 GO:0043200| response to amino acid stimulus GLRB;CPS1;GLRA3 GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CPS1 GO:0042594| response to starvation PPARG;CPS1;ACAT1 GO:0042311| vasodilation GPX1;CPS1 GO:0032094| response to food CYP1A1;OPRM1;CPS1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;CPS1;SOD1;HTR2A GO:0072593| reactive oxygen species metabolic process GLS2;SOD1 GO:0051384| response to glucocorticoid stimulus PTGS2;CPS1 GO:0009636| response to toxin CPS1;CAT;GPX1;CYP1A1;CYP1B1 GO:0008283| cell proliferation HTR1A;GLUL;GPX1;CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1;CPS1 GO:0010043| response to zinc ion CPS1;AANAT GO:0001889| liver development CYP1A1;ACAT1;CPS1 GO:0008152| metabolic process SMPD1;CPS1;ACAT1 GO:0071320| cellular response to cAMP AANAT;CPS1 GO:0014047| glutamate secretion TRPV1;GLS2 20551:[DB14011 DB07882] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07882|4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID IGKC common genes common pathways GO:0045087| innate immune response IGKC;PPARG GO:0002376| immune system process IDO1;IGKC GO:0006955| immune response IGKC;OPRD1;CNR2 GO:0001895| retina homeostasis SOD1;IGKC 20552:[DB14011 DB08766] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08766|Zofenoprilat LAP3 common genes common pathways 20553:[DB14011 DB01809] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0006919| activation of caspase activity PPARG;RET GO:0007165| signal transduction CHRNA7;RET;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0065009| regulation of molecular function RET;TRPV1 GO:0010976| positive regulation of neuron projection development CNR1;RET GO:0006954| inflammatory response CNR2;PTGS2;HCK;ALOX5;PTGS1;TRPV1;IDO1;ALOX15 GO:0016032| viral reproduction HTR2A;HCK;VDAC1 GO:0050727| regulation of inflammatory response HCK;PTGS2 GO:0007399| nervous system development RET;GLRB;SMPD1 GO:0001657| ureteric bud development CAT;RET GO:0010628| positive regulation of gene expression RET;TRPV4 GO:0002376| immune system process HCK;IDO1 GO:0048265| response to pain TRPV1;TRPA1;RET GO:0042493| response to drug RET;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RET GO:0008284| positive regulation of cell proliferation CHRNA7;HCK;HTR1A;HTR2A;PTGS2;HMGCR GO:0071300| cellular response to retinoic acid PPARG;RET GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;HCK GO:0007155| cell adhesion HCK;RET;CYP1B1 GO:0045087| innate immune response HCK;PPARG GO:0030838| positive regulation of actin filament polymerization ALOX15;HCK 20554:[DB14011 DB00833] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;CACNA1H;ABCB11 GO:0019430| removal of superoxide radicals MPO;SOD1 GO:0098656| SLC22A8;VDAC1 GO:0009636| response to toxin CYP1A1;CYP1B1;SLC22A8;CAT;GPX1 GO:0006811| ion transport TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;CACNA1G;SLC15A1;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;CACNA1H;SLC22A8;GLRA3;SLC15A2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;MPO;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;MPO GO:0043312| neutrophil degranulation ALOX5;MPO;CAT GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MPO;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0032094| response to food CYP1A1;MPO;OPRM1 GO:0055114| oxidation-reduction process CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;MPO;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2 GO:0006979| response to oxidative stress PTGS1;MPO;GPX1;CAT;PTGS2;SOD1 GO:0006810| transport ABCG2;TRPV1;CACNA1I;SLC15A1;ABCC1;TRPV2;ABCB11;SLC15A2 GO:0007568| aging MPO;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CYP1A1 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;SLC15A1;ABCC1;CACNA1G;TRPV2;SLC22A8;SLC15A2;ABCB11;TRPV3;CACNA1H 20555:[DB14011 DB08763] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08763|[N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20556:[DB14011 DB02326] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02326|1-Hydroxyamine-2-Isobutylmalonic Acid MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 20557:[DB14011 DB01765] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01765|(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid CSNK2A1 common genes common pathways GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;HTR1A;GPR55;CSNK2A1;OPRD1;CNR2;OPRM1;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;CSNK2A1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0048511| rhythmic process PPARG;CSNK2A1;AANAT GO:0006915| apoptotic process VDAC1;CSNK2A1;GPX1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;CSNK2A1;HMGCR;CHRNA7 20558:[DB14011 DB01549] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0051481| reduction of cytosolic calcium ion concentration DRD2;OPRM1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GRIN3A;DRD2;GLRB;TRPV1;GLRA3;OPRM1;CHRNA7;SLC29A1 GO:0032228| regulation of synaptic transmission, GABAergic DRD2;CNR1 GO:0007628| adult walking behavior GLRB;DRD2;GLRA1 GO:0033602| negative regulation of dopamine secretion CNR1;DRD2 GO:0007626| locomotory behavior DRD2;SOD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;DRD2;PPARG GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;DRD2;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0043278| response to morphine CNR1;OPRM1;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic DRD2;HTR2A GO:0035094| response to nicotine DRD2;CNR1;CHRNA7 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;DRD2;TRPV1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway DRD2;GPR18;PPARG;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;TRPV4;DRD2;TRPM8 GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;DRD2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;DRD2;TRPV4;ALOX15 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;GLRA1;TRPA1;GRIN3A;TRPV1;GLRB GO:0014059| regulation of dopamine secretion DRD2;HTR2A GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;DRD2 GO:0009416| response to light stimulus DRD2;AANAT GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DRD2 GO:0048678| response to axon injury DRD2;SOD1 GO:0045471| response to ethanol DRD2;GRIN3A;CAT;CNR1;SOD1;OPRM1;HMGCR GO:0045776| negative regulation of blood pressure CNR1;DRD2 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0035556| intracellular signal transduction PLA2G1B;DRD2 GO:0048148| behavioral response to cocaine HTR2A;DRD2 GO:0001659| temperature homeostasis DRD2;TRPV1;HTR2A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;DRD2 GO:0048149| behavioral response to ethanol DRD2;OPRM1 GO:0008542| visual learning DRD2;HMGCR GO:0001964| startle response GLRA1;GLRB;DRD2 GO:0006816| calcium ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;TRPA1;GRIN3A GO:0001975| response to amphetamine DRD2;SOD1;CNR2 GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;DRD2;PPARG;GPR18;SMPD1 GO:1900273| DRD2;CHRNA7 GO:0050482| arachidonic acid secretion DRD2;PLA2G1B GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;TRPV3;OPRM1;CACNA1H;TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;GRIN3A;CACNA1G GO:0014854| response to inactivity DRD2;CAT GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0009636| response to toxin GPX1;CAT;CYP1A1;DRD2;CYP1B1 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;GRIN3A;TRPA1;GLRA1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;DRD2;CYP1B1;PPARG GO:0030336| negative regulation of cell migration DRD2;CYP1B1 20559:[DB14011 DB06788] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06788|Histrelin GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PPARG;GPR18;GNRHR GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;GNRHR;CACNA1I;PLA2G1B 20560:[DB14011 DB03612] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2;HADH GO:0042493| response to drug CAT;HTR2A;SOD1;HADH;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;GPX1;ALOX5;PTGS1;SOD1;HADH;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0006635| fatty acid beta-oxidation HADH;ACAT1 GO:0014823| response to activity CAT;HADH GO:0032868| response to insulin stimulus TRPV4;CAT;AANAT;HADH GO:0009725| response to hormone stimulus ACAT1;HADH GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;HADH;PTGS1;NAAA;GPX1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6 20561:[DB14011 DB08399] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08399|PICEATANNOL ATP5B common genes common pathways GO:0001649| osteoblast differentiation ATP5B;CAT GO:0006811| ion transport TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPA1;GLRA1;CACNA1G;ATP5B;CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3 GO:0001525| angiogenesis ATP5B;CYP1B1;PTGS2 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;ATP5B;CYP2C9;PPARG 20562:[DB14011 DB02422] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02422|Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside MAN1B1 common genes common pathways GO:0008152| metabolic process SMPD1;MAN1B1;ACAT1 20563:[DB14011 DB07597] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07597|CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways GO:0032259| methylation CYP1A2;PNMT 20564:[DB14011 DB08287] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08287|(1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;GPR55 GO:1903146| CTSK;VDAC1 20565:[DB14011 DB02457] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;PTGS1;ALOX5;GPX1;CRYZ;CYP1A1;CYP2C9;GSR;IDO1;CYP2C19;CYP2D6;LIPF;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0016042| lipid catabolic process PLA2G1B;LIPF;DAGLA;NAPEPLD GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;LIPF;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0006641| triglyceride metabolic process LIPF;CAT;GPX1 20566:[DB14011 DB04057] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways GO:0031100| organ regeneration PPARG;ATIC GO:0006139| nucleobase-containing compound metabolic process SLC29A1;ATIC GO:0008152| metabolic process ACAT1;ATIC;SMPD1 20567:[DB14011 DB08831] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08831|2-deoxyglucose SLC2A1 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCC1;SLC2A1 GO:0050796| regulation of insulin secretion CNR1;SLC2A1 GO:0032868| response to insulin stimulus TRPV4;CAT;AANAT;SLC2A1 GO:0071260| cellular response to mechanical stimulus SLC2A1;PTGS2 GO:0006970| response to osmotic stress TRPV4;SLC2A1 GO:0007565| female pregnancy IDO1;SLC2A1 GO:0015758| glucose transport SLC2A1;PLA2G1B GO:0055085| transmembrane transport TRPV2;CACNA1H;SLC2A1;TRPV3;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 20568:[DB14011 DB12323] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12323|Radotinib ABL1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0007155| cell adhesion ABL1;CYP1B1 GO:0045087| innate immune response ABL1;PPARG GO:0034599| cellular response to oxidative stress ABL1;GSR;GPX1;CAT;SOD1 GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;ABL1;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0006915| apoptotic process VDAC1;ABL1;GPX1 GO:0048538| thymus development SOD1;ABL1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;ABL1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ABL1 GO:0001934| positive regulation of protein phosphorylation ABL1;CHRNA7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;ABL1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ABL1;OPRM1;HTR2A 20569:[DB14011 DB01840] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process ISYNA1;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9 20570:[DB14011 DB02308] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02308|4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-Aminium PRSS3 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS3 GO:0043542| endothelial cell migration CYP1B1;PRSS3 GO:0043312| neutrophil degranulation CAT;ALOX5;PRSS3 20571:[DB14011 DB02358] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02358|LY374571 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;MTHFD1;CRYZ;CYP2C9;CYP1A1;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0008152| metabolic process SMPD1;MTHFD1;ACAT1 GO:0007507| heart development MTHFD1;PPARG 20572:[DB14011 DB04864] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04864|Huperzine A ACHE common genes common pathways GO:0008283| cell proliferation CYP1A1;ACHE;HTR1A;GPX1 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0051262| protein tetramerization HMGCR;ACHE;CAT GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0009611| response to wounding GPX1;ACHE;CYP1A1 GO:0007517| muscle organ development ACHE;CACNA1H GO:0007155| cell adhesion ACHE;CYP1B1 20573:[DB14011 DB11693] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways GO:0007507| heart development PPARG;PPP3R1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPP3R1;PLA2G1B;PPARG 20574:[DB14011 DB06834] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways GO:0016032| viral reproduction HTR2A;VDAC1;SYK GO:0006954| inflammatory response SYK;TRPV1;ALOX15;IDO1;PTGS2;CNR2;ALOX5;PTGS1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SYK;HTR2A GO:0019370| leukotriene biosynthetic process SYK;PLA2G1B;ALOX5 GO:0035556| intracellular signal transduction PLA2G1B;SYK GO:0001525| angiogenesis SYK;CYP1B1;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;SYK;TRPA1 GO:0008283| cell proliferation SYK;CYP1A1;GPX1;HTR1A GO:0071404| cellular response to low-density lipoprotein particle stimulus SYK;PPARG GO:0030593| neutrophil chemotaxis PLA2G1B;SYK GO:0045087| innate immune response SYK;PPARG GO:0000187| activation of MAPK activity PLA2G1B;SYK;CHRNA7;SOD1 GO:0002376| immune system process SYK;IDO1 GO:0048514| blood vessel morphogenesis SYK;CYP1B1 20575:[DB14011 DB07715] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07715|Emodin CSNK2A1;fabZ;AHR common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;CSNK2A1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0009636| response to toxin CAT;GPX1;CYP1A1;AHR;CYP1B1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;AHR;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AHR;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2;GPX1 GO:0010468| regulation of gene expression AHR;CYP1A2 GO:0048511| rhythmic process AHR;PPARG;CSNK2A1;AANAT GO:0045892| negative regulation of transcription, DNA-dependent AHR;PPARG GO:0006915| apoptotic process VDAC1;AHR;GPX1;CSNK2A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation CSNK2A1;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0009410| response to xenobiotic stimulus AHR;GPX1 GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;AHR;CSNK2A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AHR 20576:[DB14011 DB08691] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08691|ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate CLK1;CLK3 common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;CLK1 20577:[DB14011 DB00161] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;CACNA1H;SLC16A10;TRPV3;TRPV2 GO:0009062| fatty acid catabolic process PCCB;FAAH GO:0009083| branched chain family amino acid catabolic process BCAT1;ACAT1 GO:0008283| cell proliferation CYP1A1;HTR1A;BCAT1;GPX1 GO:0008152| metabolic process ACAT1;BCAT1;SMPD1 20578:[DB14011 DB00553] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00553|Methoxsalen CYP1A2;CYP2A6;CYP1A1;CYP2A13 common genes CYP1A2;CYP1A1 common pathways GO:0010041| response to iron(III) ion CYP1A1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP2A6;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2A6;CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0009611| response to wounding GPX1;CYP1A1 GO:0007568| aging CYP1A1;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1 GO:0010468| regulation of gene expression CYP1A2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;CYP1A2;PTGS2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP2A13;CYP2A6;CYP1A2 GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;CYP1A2;OPRM1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0009308| amine metabolic process CYP1A1 GO:0009804| coumarin metabolic process CYP2A13;CYP2A6;CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP2A6;CYP2A13;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0043010| camera-type eye development CYP1A1 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:1900087| CYP1A1 GO:0032502| developmental process CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0070365| hepatocyte differentiation CYP1A1 GO:0009636| response to toxin CAT;GPX1;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009624| response to nematode CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2A13;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;PTGS1;NAAA;GPX1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0009692| ethylene metabolic process CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0070988| demethylation CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2A6;CYP2C19;CYP2C9 20579:[DB14011 DB06612] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06612|Mepolizumab IL5 common genes common pathways GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;IL5;PTGS1;ALOX5;PTGS2;CNR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL5 GO:0006955| immune response OPRD1;CNR2;IL5 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL5 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;IL5 GO:0045893| positive regulation of transcription, DNA-dependent IL5;PPARG GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;IL5 20580:[DB14011 DB05152] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05152|NGX267 CHRM1 common genes common pathways GO:0050890| cognition CHRM1;CHRNA7 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRM1;CHRNA7 GO:0008283| cell proliferation GPX1;HTR1A;CHRM1;CYP1A1 GO:0007399| nervous system development CHRM1;GLRB;SMPD1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRM1;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;CHRM1;HTR1A;HTR2A 20581:[DB14011 DB01940] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01940|Balanol Analog 2 PRKACA common genes common pathways GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0061136| regulation of proteasomal protein catabolic process GPX1;PRKACA GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2;PRKACA 20582:[DB14011 DB01931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;GRIN1;GPR12;HTR2A;CHRNA7 GO:0042391| regulation of membrane potential CACNA1G;GLRA1;GLRB;CACNA1H;GRIN1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential GRIN1;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PLA2G1B;PPARG GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;SLC29A1;CHRNA7;GRIN1;OPRM1;GLRA3 GO:0007612| learning PTGS2;GRIN1;VDAC1 GO:0010524| positive regulation of calcium ion transport into cytosol GRIN1;PLA2G1B GO:0043523| regulation of neuron apoptosis GPX1;GRIN1 GO:0007611| learning or memory GRIN1;CNR1;CHRNA7 GO:0043278| response to morphine OPRM1;GRIN1;CNR1 GO:0050905| neuromuscular process GLRB;GLRA1;GRIN1 GO:0065009| regulation of molecular function GRIN1;TRPV1 GO:0007613| memory CHRNA7;HTR2A;CNR1;GRIN1;PTGS2 GO:0043576| regulation of respiratory gaseous exchange GLRA1;GRIN1 GO:0001975| response to amphetamine CNR2;GRIN1;SOD1 GO:0006812| cation transport GRIN1;TRPM8 GO:0008344| adult locomotory behavior OPRD1;GRIN1 GO:0006811| ion transport TRPV2;CHRNA7;GRIN1;CACNA1H;TRPV3;GLRA3;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;GRIN1;PTGS2;SOD1;CNR1 GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;GRIN1;OPRM1 GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;PTGS2;CNR2;GRIN1;OPRM1;OPRD1 GO:0008542| visual learning GRIN1;HMGCR GO:0001964| startle response GRIN1;GLRB;GLRA1 GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G;CHRNA7;TRPV2;TRPV3;CACNA1H;GRIN1 GO:0043524| negative regulation of neuron apoptosis SOD1;GRIN1 20583:[DB14011 DB03368] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03368|5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione MMP3 common genes common pathways 20584:[DB14011 DB04954] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04954|Tecadenoson ADORA1 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;ADORA1;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0097756| ADORA1;HMGCR;PTGS2 GO:0001666| response to hypoxia CYP1A1;ADORA1;CHRNA7;CAT GO:0002674| negative regulation of acute inflammatory response ADORA1;PPARG GO:0016042| lipid catabolic process NAPEPLD;DAGLA;PLA2G1B;ADORA1 GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0043066| negative regulation of apoptotic process ADORA1;CAT;GPX1;SOD1;HMGCR;PTGS2 GO:0035307| positive regulation of protein dephosphorylation ADORA1;SMPD1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;ADORA1;GLRA1;CHRNA7;SLC29A1;GLRA3;OPRM1 GO:0050728| negative regulation of inflammatory response CNR2;ADORA1 GO:0051967| negative regulation of synaptic transmission, glutamatergic ADORA1;HTR2A GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA1 GO:0007165| signal transduction HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;ADORA1;SMPD1;PLA2G1B;CACNA1I GO:0050890| cognition ADORA1;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway ADORA1;OPRM1;OPRD1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;ADORA1;OPRM1;PTGS2 GO:0032229| negative regulation of synaptic transmission, GABAergic ADORA1;CNR2 GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;ADORA1 GO:0045777| positive regulation of blood pressure CNR1;ADORA1 GO:0001659| temperature homeostasis HTR2A;GPX1;ADORA1;TRPV1 GO:0007399| nervous system development SMPD1;ADORA1;GLRB GO:0045776| negative regulation of blood pressure CNR1;ADORA1 GO:0006954| inflammatory response ADORA1;TRPV1;ALOX15;IDO1;PTGS2;CNR2;ALOX5;PTGS1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1;ADORA1 20585:[DB14011 DB02659] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes ABCC1;PLA2G1B common pathways GO:0009409| response to cold TRPM8;MT-CO2;PPARG;TRPA1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CES1;CYP3A4;CYP1A2;CYP3A7 GO:0035556| intracellular signal transduction PLA2G1B GO:0008152| metabolic process SMPD1;CES1;ACAT1 GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;FABP6;PPARG;CYP2C9;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15 GO:0034775| glutathione transmembrane transport ABCC1 GO:0036148| PLA2G1B GO:0036149| PLA2G1B GO:0006357| regulation of transcription from RNA polymerase II promoter NR1H4;PPARG GO:0006351| transcription, DNA-dependent NR1H4;PPARG;ESRRG GO:0035725| sodium ion transmembrane transport ABCB11;CACNA1H;CACNA1I;CACNA1G GO:0043401| steroid hormone mediated signaling pathway NR1H4;PPARG;ESRRG GO:0045471| response to ethanol CAT;SOD1;CNR1;HMGCR;OPRM1;FECH GO:0016032| viral reproduction HTR2A;VDAC1;SLC10A1 GO:0006954| inflammatory response ALOX5;PTGS1;NR1H4;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0009408| response to heat SOD1;TRPV3;TRPV2;ABCC2;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT GO:0007595| lactation SLC29A1;MT-CO2 GO:0032637| interleukin-8 production PLA2G1B GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0007565| female pregnancy IDO1;ABCC2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;FABP1 GO:0050482| arachidonic acid secretion PLA2G1B GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;NR1H4;HTR1A;GPR55;HTR2A;CNR1;GPR12;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;GPBAR1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;FABP1;PPARG;CYP1A1 GO:0099039| ABCC1 GO:0046718| entry of virus into host cell SLC10A1;HTR2A GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC3;ABCC1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B GO:0045740| positive regulation of DNA replication PLA2G1B GO:0036150| PLA2G1B GO:0008285| negative regulation of cell proliferation PPARG;FABP6;CYP1B1;PTGS2;OPRM1 GO:0098656| VDAC1;SLC22A7;SLC22A8 GO:0061844| PLA2G1B GO:0007584| response to nutrient CNR1;HMGCR;COX4I1;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1;FABP1 GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0002227| innate immune response in mucosa PLA2G1B GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;ABCC4;AANAT;ACAT1;CYP1A2;PTGS2 GO:0009636| response to toxin GPX1;CAT;CES1;SLC22A8;CYP1B1;CYP1A1 GO:0032088| negative regulation of NF-kappaB transcription factor activity NR1H4;CAT;CYP1B1 GO:0006811| ion transport TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;SLC10A2;SLC10A1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;SLC22A7;CHRNA7;CACNA1H;SLCO1A2;TRPV3;SLCO1B3;SLCO1B1;GLRA3;SLC22A8 GO:0046470| phosphatidylcholine metabolic process PLA2G1B GO:0006855| drug transmembrane transport ABCC3;ABCC1;ABCG2;ABCC2;ABCB1 GO:0044240| multicellular organismal lipid catabolic process PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;NR1H4;FABP1;PTGS2;CAT;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;PLA2G1B;ESRRG;PPARG GO:0002576| platelet degranulation SOD1;ABCC4 GO:0010288| response to lead ion FECH;CAT GO:0045087| innate immune response NR1H4;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR1H4;PPARG;TRPV4;TRPV1 GO:0036151| PLA2G1B GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;CYP1A1;ABCC2;IDO1 GO:0006695| cholesterol biosynthetic process HMGCR;CES1 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2;HMGCR GO:0010243| response to organic nitrogen ABCC4;PTGS2;TRPV1 GO:0050728| negative regulation of inflammatory response CNR2;NR1H4 GO:0060326| cell chemotaxis ABCC1 GO:0007015| actin filament organization PLA2G1B;TRPV4 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESRRG;NR1H4 GO:0045893| positive regulation of transcription, DNA-dependent ESRRG;PPARG GO:0022900| electron transport chain CYP1A2;GSR;IDO1;COX7A1;MT-CO2 GO:0099133| ABCC4;ABCC3;ABCC1;ABCC2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESRRG;NR1H4 GO:0030593| neutrophil chemotaxis PLA2G1B GO:0046685| response to arsenic-containing substance CYP1A1;FECH;ABCC2 GO:0006691| leukotriene metabolic process ALOX5;ALOX15;ABCC1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B GO:0042493| response to drug CAT;ABCC4;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;ABCC2;ABCB1;PPARG;CYP1A1;TRPA1;FECH;SMPD1;ABCC1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;MT-CO2;MT-CO1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;ADH1C;CAT;ABCC4;PTGS1;ALOX5;GPX1 GO:0019731| antibacterial humoral response PLA2G1B GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;MT-CO1;ABCC2 GO:0098869| GSR;PTGS1;GPX1;CAT;FABP1;PTGS2 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;NR1H4;GPR18 GO:0002376| immune system process IDO1;NR1H4 GO:0042593| glucose homeostasis NR1H4;CNR1;PPARG;TRPV4 GO:0036152| PLA2G1B GO:0002446| neutrophil mediated immunity PLA2G1B GO:0009235| cobalamin metabolic process ABCC1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GPBAR1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0009060| aerobic respiration MT-CO1;COX6A2;CAT GO:0006810| transport ABCG2;ABCC2;TRPV1;CACNA1I;ABCB1;SLC10A2;SLC10A1;ABCC3;ABCC1;TRPV2;ABCB11 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;MT-CO1;CYP1A1 GO:0015909| long-chain fatty acid transport PPARG;FABP1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2;FABP1 GO:0050778| positive regulation of immune response PLA2G1B GO:0046688| response to copper ion MT-CO1;AANAT;SOD1 GO:0032431| activation of phospholipase A2 activity PLA2G1B GO:0015758| glucose transport PLA2G1B GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2;ABCC4 GO:0006644| phospholipid metabolic process PLA2G1B;NAPEPLD GO:0009416| response to light stimulus AANAT;FECH GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0016042| lipid catabolic process NAPEPLD;PLA2G1B;DAGLA GO:0007043| cell-cell junction assembly NR1H4;TRPV4 GO:0030855| epithelial cell differentiation CES1;VDAC1;PPARG GO:0050714| positive regulation of protein secretion PLA2G1B GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0055085| transmembrane transport CACNA1G;ABCC1;ABCC3;TRPA1;VDAC1;ABCB1;CACNA1I;TRPV4;TRPV1;SLC10A1;SLC10A2;ABCG2;TRPM8;ABCC2;CACNA1H;SLCO1A2;TRPV3;SLCO1B3;SLC22A8;ABCB11;SLCO1B1;TRPV2;ABCC4;SLC22A7 20586:[DB14011 DB05110] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05110|VIR201 IFNG common genes common pathways GO:0000060| protein import into nucleus, translocation OPRD1;IFNG GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;IFNG GO:0001934| positive regulation of protein phosphorylation IFNG;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;IFNG GO:0006955| immune response CNR2;OPRD1;IFNG GO:0050796| regulation of insulin secretion CNR1;IFNG GO:0048662| negative regulation of smooth muscle cell proliferation IFNG;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter IFNG;PPARG;TRPV4;TRPV1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;IFNG;CHRNA7 GO:0009615| response to virus CYP1A1;IFNG GO:0035722| interleukin-12-mediated signaling pathway IFNG;SOD1 GO:0032735| positive regulation of interleukin-12 production IFNG;IDO1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;IFNG;PTGS2;OPRM1 GO:0006915| apoptotic process GPX1;IFNG;VDAC1 GO:0045892| negative regulation of transcription, DNA-dependent IFNG;PPARG GO:0010628| positive regulation of gene expression TRPV4;IFNG 20587:[DB14011 DB04301] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04301|Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone Hydrate PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 20588:[DB14011 DB04307] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04307|5-Hydroxy-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CAT;CNR1;SOD1;OPRM1;HMGCR GO:0010269| response to selenium ion GPX1;MAOB GO:0009636| response to toxin CAT;GPX1;CYP1A1;MAOB;CYP1B1 GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0022900| electron transport chain CYP1A2;MAOB;IDO1;GSR GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;MAOB GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;MAOB;CRYZ;CYP2C9;CYP1A1;PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;CNR2;PTGS2;IDO1;CYP1A1;MAOB GO:0050665| hydrogen peroxide biosynthetic process MAOB;CYP1A1;CYP1A2;SOD1 20589:[DB14011 DB04899] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways GO:0001503| ossification ALOX15;NPR2 GO:0035556| intracellular signal transduction NPR1;NPR2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway NPR1;TRPA1;TRPV1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;NPR3 GO:0008217| regulation of blood pressure NPR2;NPR3;PPARG;NPR1;PTGS1;SOD1;PTGS2 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;NPR3;NPR1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;NPR3 GO:0016525| negative regulation of angiogenesis NPR1;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger NPR3;HTR2A;OPRM1;OPRD1 GO:0030308| negative regulation of cell growth NPR1;PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;NPR1;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 20590:[DB14011 DB00432] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes SLC29A1 common pathways GO:0033189| response to vitamin A PPARG;CYP1A1;TYMS;CAT GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;TYMS;PPARG GO:0034097| response to cytokine stimulus TYMS;PTGS2;AANAT GO:0002576| platelet degranulation SOD1;ALB GO:0032259| methylation CYP1A2;TYMS GO:0043066| negative regulation of apoptotic process ALB;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0007623| circadian rhythm TYMS;AANAT GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;SLC22A6;CACNA1G;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2 GO:0006820| anion transport GLRA1;SLC22A6;VDAC1 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0098869| PTGS2;CAT;GPX1;PTGS1;ALB;GSR GO:1901642| SLC28A1;SLC29A2;SLC29A1 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0007568| aging CYP1A1;TYMS;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT GO:0007595| lactation SLC29A1 GO:0051289| protein homotetramerization TK1;CAT;TRPA1;CRYZ;TRPM8;TRPV1 GO:0015858| nucleoside transport SLC28A1;SLC29A1;SLC29A2 GO:0015862| uridine transport SLC29A1 GO:0008152| metabolic process TYMP;ACAT1;SMPD1 GO:0045471| response to ethanol TYMS;CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0001525| angiogenesis CYP1B1;TYMP;PTGS2 GO:0030431| sleep CACNA1I;HTR2A;SLC29A1 GO:0098656| SLC22A6;VDAC1 GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR GO:0001895| retina homeostasis SOD1;ALB GO:0006139| nucleobase-containing compound metabolic process SLC28A1;SLC29A2;TK1;SLC29A1 GO:0008283| cell proliferation GPX1;HTR1A;SLC29A2;CYP1A1 GO:0009636| response to toxin CYP1B1;TYMS;CYP1A1;GPX1;CAT GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;TYMS;AANAT;ACAT1;CYP1A2;PTGS2 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 20591:[DB14011 DB05829] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05829|Parathyroid hormone PTH1R;PTH2R common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTH1R;PTGS2;HMGCR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;PTH1R;OPRD1;HTR2A GO:0006874| cellular calcium ion homeostasis PTH1R;HTR2A;GPR12;CHRNA7;TRPV4;TRPM8 GO:0030282| bone mineralization PTH1R;PTGS2;ALOX15 GO:0007568| aging CYP1A1;CAT;HMGCR;PTH1R;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;PTH2R;OPRD1;CNR2;PTH1R;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;PTH1R;CNR2;OPRM1 GO:0001503| ossification PTH1R;ALOX15 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;PTH1R GO:0007166| cell surface receptor linked signaling pathway PTH1R;TRPA1;PTH2R;TRPV1 GO:0048469| cell maturation PTH1R;PPARG GO:0007165| signal transduction GPR18;PPARG;SMPD1;PTH2R;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;PTH1R;CNR2;CHRNA7 GO:0045453| bone resorption GPR55;PTH1R GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;PTH1R;OPRM1;TRPV4;TRPV1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PTH1R;CYP1B1;PPARG 20592:[DB14011 DB06194] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06194|Elocalcitol VDR common genes common pathways GO:0010628| positive regulation of gene expression VDR;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG GO:0046697| decidualization VDR;PTGS2 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;HTR2A;GPR12;CHRNA7;VDR GO:0006355| regulation of transcription, DNA-dependent PPARG;VDR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;PPARG;TRPV1;TRPV4 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;VDR GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;VDR GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;VDR;TRPV2;TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1 GO:0007595| lactation VDR;SLC29A1 GO:0006351| transcription, DNA-dependent PPARG;VDR GO:0043401| steroid hormone mediated signaling pathway VDR;PPARG 20593:[DB14011 DB12116] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0010468| regulation of gene expression AHR;DNMT1;CYP1A2 GO:0045892| negative regulation of transcription, DNA-dependent DNMT1;AHR;PPARG GO:0048511| rhythmic process AHR;PPARG;AANAT GO:0010628| positive regulation of gene expression TRPV4;DNMT1 GO:0006915| apoptotic process GPX1;VDAC1;AHR GO:0000122| negative regulation of transcription from RNA polymerase II promoter DNMT1;TRPV4;TRPV1;PPARG GO:0032259| methylation DNMT1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;AHR;PLA2G1B GO:0071230| cellular response to amino acid stimulus DNMT1;GLRA1 GO:0009410| response to xenobiotic stimulus GPX1;AHR GO:0042127| regulation of cell proliferation DNMT1;PTGS1;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AHR GO:0006355| regulation of transcription, DNA-dependent DNMT1;AHR;PPARG GO:0009636| response to toxin GPX1;CAT;CYP1B1;AHR;CYP1A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP2D6;CYP2C19;AHR;CYP2C9 GO:0006351| transcription, DNA-dependent DNMT1;AHR;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG 20594:[DB14011 DB02104] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;DHFR;CRYZ;CYP2C9;CYP1A1 20595:[DB14011 DB05846] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05846|Mito-4509 APP common genes common pathways GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0050808| synapse organization CHRNA7;APP GO:0019731| antibacterial humoral response PLA2G1B;APP GO:0051897| positive regulation of protein kinase B signaling cascade APP;GPX1 GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0007611| learning or memory CNR1;CHRNA7;APP GO:0007612| learning PTGS2;VDAC1;APP GO:0008203| cholesterol metabolic process APP;CAT;HMGCR GO:0046330| positive regulation of JNK cascade APP;TRPV4 GO:1905906| CHRNA7;APP GO:0002576| platelet degranulation APP;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;APP;PLA2G1B GO:0007626| locomotory behavior APP;OPRM1;SOD1 GO:0010288| response to lead ion CAT;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;APP;PPARG GO:0007155| cell adhesion CYP1B1;APP GO:0045087| innate immune response PPARG;APP GO:0006915| apoptotic process VDAC1;APP;GPX1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;APP;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0051262| protein tetramerization HMGCR;CAT;APP GO:2000463| positive regulation of excitatory postsynaptic membrane potential APP;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;APP;HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 GO:0098815| CHRNA7;APP GO:0010468| regulation of gene expression CYP1A2;APP GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;APP GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TRPV1;OPRM1;PTGS2 GO:0051260| protein homooligomerization GLRA1;APP;ACAT1;GLRA3 GO:0010629| negative regulation of gene expression APP;OPRD1 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;APP;HTR2A;GLRA3;OPRM1;OPRD1 GO:0071320| cellular response to cAMP APP;AANAT GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:1902004| CHRNA7;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;APP GO:0008542| visual learning APP;HMGCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;APP GO:0001774| microglial cell activation TRPV1;APP GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;APP;SOD1;CNR1;PTGS2 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:1990090| TRPV1;APP GO:0007399| nervous system development GLRB;SMPD1;APP GO:0008344| adult locomotory behavior APP;OPRD1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;APP;CYP1B1 GO:0032930| positive regulation of superoxide anion generation SOD1;APP GO:0061844| APP;PLA2G1B GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRD1;OPRM1 GO:0007613| memory APP;PTGS2;CNR1;HTR2A;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration APP;TRPV4;TRPV1;OPRM1;HTR2A GO:1900273| APP;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;APP 20596:[DB14011 DB04129] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04129|Willardiine GRIA2 common genes common pathways GO:0007165| signal transduction CHRNA7;GRIA2;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0006811| ion transport GRIA2;TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GRIA2;GLRA1;CACNA1G;GLRB;VDAC1 GO:0034220| ion transmembrane transport GLRA3;GRIA2;CHRNA7;GLRA1;TRPA1;TRPV1;GLRB GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;GRIA2;SLC29A1;GLRA3;OPRM1;GLRB;TRPV1;GLRA1 20597:[DB14011 DB08802] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08802|Isothipendyl HRH1 common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;HRH1;OPRM1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;HRH1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PPARG;GPR18 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;HRH1;CNR2;PTGS2 GO:0008542| visual learning HRH1;HMGCR GO:0045907| positive regulation of vasoconstriction HTR2A;HRH1;PTGS2 GO:0007165| signal transduction CNR2;OPRM1;HRH1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B GO:0007613| memory HRH1;PTGS2;CNR1;HTR2A;CHRNA7 20598:[DB14011 DB02035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways GO:0007601| visual perception PPT1;CYP1B1;GLRB;CRYZ;GLRA1 GO:0007420| brain development PPT1;ACAT1 GO:0050896| response to stimulus TRPM8;TRPA1;PPT1 GO:0007399| nervous system development PPT1;GLRB;SMPD1 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;GLRA1;OPRD1;PPT1;OPRM1;GLRA3;HTR2A GO:0043524| negative regulation of neuron apoptosis SOD1;PPT1 GO:0016042| lipid catabolic process DAGLA;PLA2G1B;NAPEPLD;PPT1 GO:0030308| negative regulation of cell growth PPARG;PPT1 GO:0043066| negative regulation of apoptotic process HMGCR;PPT1;PTGS2;SOD1;GPX1;CAT 20599:[DB14011 DB01051] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01051|Novobiocin gyrB;topA;SLC22A6;SLC22A8;SLC22A11;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1 common genes ABCG2 common pathways GO:0098656| SLC22A8;SLC22A6;VDAC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport SLCO1B3;SLCO1B1;SLC22A8;GLRA3;CACNA1H;TRPV3;CHRNA7;SLC22A11;TRPV2;TRPA1;GLRA1;CACNA1G;TRPM8;SLCO2B1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 GO:0046415| urate metabolic process ABCG2;SLC22A11 GO:0055085| transmembrane transport SLC22A11;TRPV2;SLCO1B1;SLC22A8;SLCO1B3;TRPV3;CACNA1H;SLCO2B1;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;ABCC1;SLC22A6;CACNA1G GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0006810| transport TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I GO:0015886| heme transport ABCG2 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0033344| cholesterol efflux ABCG2 20600:[DB14011 DB07986] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07986|[4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID MMP3 common genes common pathways 20601:[DB14011 DB04891] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04891|Becocalcidiol MED1;VDR common genes common pathways GO:0010628| positive regulation of gene expression TRPV4;MED1;VDR GO:0045892| negative regulation of transcription, DNA-dependent PPARG;VDR GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;HTR2A;GPR12;VDR;CHRNA7 GO:0031100| organ regeneration PPARG;MED1 GO:0046697| decidualization PTGS2;VDR GO:0006367| transcription initiation from RNA polymerase II promoter VDR;PPARG;MED1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;MED1 GO:0045444| fat cell differentiation MED1;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;MED1;VDR GO:0030224| monocyte differentiation PPARG;MED1 GO:0043066| negative regulation of apoptotic process MED1;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;MED1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;PLA2G1B;MED1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;MED1;TRPV4;TRPV1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1;VDR GO:0006702| androgen biosynthetic process MED1;CYP17A1 GO:0043010| camera-type eye development CYP1A1;MED1 GO:0007420| brain development ACAT1;MED1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;VDR;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;MED1;CNR1;HMGCR GO:0035357| peroxisome proliferator activated receptor signaling pathway MED1;PPARG GO:0006816| calcium ion transport CACNA1G;TRPA1;TRPV4;CACNA1I;TRPV1;TRPM8;TRPV3;CACNA1H;VDR;TRPV2;CHRNA7 GO:0007595| lactation SLC29A1;VDR;MED1 GO:0007507| heart development PPARG;MED1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;MED1 GO:0006351| transcription, DNA-dependent VDR;PPARG;MED1 GO:0001889| liver development ACAT1;MED1;CYP1A1 GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR GO:0001525| angiogenesis PTGS2;MED1;CYP1B1 20602:[DB14011 DB02597] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways GO:0043312| neutrophil degranulation MME;CAT;ALOX5 GO:0001822| kidney development CAT;MME GO:0071345| cellular response to cytokine stimulus TRPV1;MME GO:0019233| sensory perception of pain TRPV1;TRPA1;OPRD1;CNR2;PTGS2;MME;OPRM1;HTR2A;CNR1 20603:[DB14011 DB02309] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways GO:0051289| protein homotetramerization HPRT1;TRPV1;TRPM8;TRPA1;CRYZ;CAT GO:0008152| metabolic process SMPD1;ATIC;ACAT1 GO:0006139| nucleobase-containing compound metabolic process SLC29A1;ATIC GO:0001975| response to amphetamine CNR2;SOD1;HPRT1 GO:0007626| locomotory behavior SOD1;OPRM1;HPRT1 GO:0031100| organ regeneration PPARG;ATIC 20604:[DB14011 DB13978] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13978|Selisistat SIRT1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide CYP1B1;SIRT1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;SIRT1;CAT GO:0032868| response to insulin stimulus AANAT;CAT;SIRT1;TRPV4 GO:0016032| viral reproduction HTR2A;VDAC1;SIRT1 GO:0050872| white fat cell differentiation PPARG;SIRT1 GO:0010629| negative regulation of gene expression SIRT1;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;SIRT1 GO:0042542| response to hydrogen peroxide SOD1;GPX1;CAT;TRPA1;SIRT1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;TRPV1;CYP1B1;SIRT1;IDO1;SMPD1;PPARG GO:0035358| regulation of peroxisome proliferator activated receptor signaling pathway ALOX15;SIRT1 GO:0001525| angiogenesis PTGS2;CYP1B1;SIRT1 GO:0006351| transcription, DNA-dependent SIRT1;PPARG GO:0007283| spermatogenesis CNR1;SOD1;SIRT1 GO:0071356| cellular response to tumor necrosis factor TRPV1;SIRT1 GO:0048511| rhythmic process AANAT;PPARG;SIRT1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SIRT1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;SIRT1 GO:0006915| apoptotic process GPX1;VDAC1;SIRT1 GO:0006979| response to oxidative stress SIRT1;CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1;SIRT1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;SIRT1 GO:0006355| regulation of transcription, DNA-dependent PPARG;SIRT1 GO:0007517| muscle organ development SIRT1;CACNA1H GO:1902176| SIRT1;GPX1 GO:0007569| cell aging SOD1;SIRT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;SIRT1;PPARG GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;SIRT1 GO:0043066| negative regulation of apoptotic process SIRT1;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;SIRT1;TRPV4 GO:0007623| circadian rhythm SIRT1;AANAT GO:0042127| regulation of cell proliferation SIRT1;PTGS1;PTGS2 GO:0030308| negative regulation of cell growth SIRT1;PPARG 20605:[DB14011 DB02547] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 20606:[DB14011 DB03573] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03573|WRR-99 CTSF common genes common pathways 20607:[DB14011 DB06429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06429|Talnetant TACR3 common genes common pathways GO:0042538| hyperosmotic salinity response TRPV4;TACR3 GO:0043278| response to morphine OPRM1;CNR1;TACR3 GO:0032355| response to estradiol stimulus CAT;TACR3;CYP1A2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;TACR3;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0007568| aging CYP1A1;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CAT;TACR3 GO:0042220| response to cocaine SMPD1;TACR3;CNR1;OPRM1 GO:0060259| regulation of feeding behavior CNR1;TACR3 GO:0007165| signal transduction CHRNA7;TACR3;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0042053| regulation of dopamine metabolic process HTR1A;TACR3 GO:0045777| positive regulation of blood pressure CNR1;TACR3 20608:[DB14011 DB04932] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0002674| negative regulation of acute inflammatory response PPARG;ADORA1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;ADORA1 GO:0031000| response to caffeine PPARG;ADORA2A GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0016042| lipid catabolic process ADORA1;PLA2G1B;DAGLA;NAPEPLD GO:0006915| apoptotic process VDAC1;ADORA2A;GPX1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;ADORA2B;PLA2G1B GO:0050714| positive regulation of protein secretion ADORA2A;PLA2G1B GO:0002087| regulation of respiratory gaseous exchange by neurological system process ADORA1;GLRA1 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;ADORA1;PPARG;ADORA2A;GPR18;ADORA2B GO:0097756| PTGS2;HMGCR;ADORA1 GO:0050728| negative regulation of inflammatory response ADORA1;ADORA2A;CNR2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;ADORA1 GO:0006355| regulation of transcription, DNA-dependent ADORA2A;PPARG GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;ADORA2A;PPARG;CYP1A1;ABCC1;SMPD1 GO:0060087| relaxation of vascular smooth muscle SOD1;ADORA1;ADORA2B GO:0043066| negative regulation of apoptotic process ADORA1;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0042311| vasodilation GPX1;ADORA2A GO:0007626| locomotory behavior ADORA2A;SOD1;OPRM1 GO:0035307| positive regulation of protein dephosphorylation SMPD1;ADORA1 GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA7;GLRA1;ADORA2A;ADORA1;TRPV1;GLRB GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;ADORA2A;PPARG;ADORA1 GO:0032229| negative regulation of synaptic transmission, GABAergic ADORA1;CNR2 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;ADORA1 GO:0042755| eating behavior OPRD1;OPRM1;ADORA2A GO:0045777| positive regulation of blood pressure ADORA1;CNR1 GO:0051881| regulation of mitochondrial membrane potential ADORA2A;SOD1;OPRD1 GO:0007165| signal transduction SMPD1;GPR18;ADORA2A;PPARG;ADORA1;ADORA2B;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 GO:0001975| response to amphetamine ADORA2A;SOD1;CNR2 GO:0050890| cognition ADORA1;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;ADORA1 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;ADORA1;ADORA2A;TRPV1;ALOX15;IDO1 GO:0007600| sensory perception TRPV2;OPRM1;ADORA2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1;ADORA1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;GPX1;PTGS2 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADORA2A;CNR1 GO:0001659| temperature homeostasis HTR2A;GPX1;ADORA1;TRPV1 GO:0007399| nervous system development SMPD1;ADORA1;GLRB GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;ADORA2B;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;ADORA1 20609:[DB14011 DB00644] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways GO:0007165| signal transduction GNRHR;GNRHR2;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GNRHR;GNRHR2;GPR18;PPARG 20610:[DB14011 DB04927] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04927|NM100060 SQLE common genes common pathways GO:0016126| sterol biosynthetic process SQLE;HMGCR GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2;SQLE GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;PTGS1;ALOX5;GPX1;SQLE GO:0006695| cholesterol biosynthetic process SQLE;HMGCR GO:0008203| cholesterol metabolic process SQLE;CAT;HMGCR GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2;SQLE GO:0045540| regulation of cholesterol biosynthetic process HMGCR;SQLE 20611:[DB14011 DB02834] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02834|IDD552 AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;AKR1B1;CYP2C9;CYP1A1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0022900| electron transport chain GSR;IDO1;AKR1B1;CYP1A2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;AKR1B1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 20612:[DB14011 DB14543] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes CYP3A7;CYP3A4;CYP3A5;ABCG2 common pathways GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4 GO:0006704| glucocorticoid biosynthetic process CYP11B1;HSD3B1;CYP17A1;HSD11B2 GO:0042593| glucose homeostasis CYP11B1;CNR1;TRPV4;PPARG GO:0002376| immune system process ANXA1;IDO1 GO:0006810| transport TRPV2;ABCG2;TRPV1;CACNA1I;ABCB1;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;GPR18;PPARG;ANXA1 GO:0032355| response to estradiol stimulus ANXA1;PTGS2;CYP1A2;CAT GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP17A1;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A7;HMGCR;CYP11B2;CYP11B1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;CNR2;OPRM1;CNR1;ANXA1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia HSD11B2;CYP1A1;CHRNA7;CAT GO:0036378| CYP3A4 GO:0055085| transmembrane transport TRPV3;SLCO1A2;CACNA1H;SLC22A8;TRPV2;ABCC1;CACNA1G;TRPA1;TRPV4;ABCB1;CACNA1I;VDAC1;TRPV1;TRPM8;ABCG2 GO:0031532| actin cytoskeleton reorganization ANXA1;TRPV4 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP2C8;CYP3A5 GO:0045087| innate immune response ANXA1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process ANXA1;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C8;CYP2C19;CYP1B1;CYP1A2 GO:0033344| cholesterol efflux ABCG2 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP3A5;CYP2D6;CYP2C9 GO:0042127| regulation of cell proliferation ANXA1;PTGS2;PTGS1 GO:0015886| heme transport ABCG2 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0006694| steroid biosynthetic process HSD3B1;CYP17A1;CYP11B2;HMGCR;CYP11B1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;CYP11B1;HMGCR;CYP11B2;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;HSD11B2;CYP17A1;HSD3B1;CYP2D6;GSR;IDO1;CYP2C8;CYP2C19;CYP1A1;CYP2C9;CRYZ GO:0032342| aldosterone biosynthetic process CYP11B1;CYP11B2;CACNA1H GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ANXA1;ABCG2;HSD11B2;ABCB1;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0032094| response to food OPRM1;CYP1A1;HSD11B2 GO:0009725| response to hormone stimulus ACAT1;ANXA1 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C8;CYP2C19;CYP1A2 GO:0007165| signal transduction CACNA1I;PLA2G1B;ANXA1;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;NR3C1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6;CYP2C8 GO:0044849| ANXA1;OPRM1 GO:0050482| arachidonic acid secretion ANXA1;PLA2G1B GO:0032870| cellular response to hormone stimulus CACNA1H;CYP11B1;CYP11B2 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:1900087| CYP1A1;ANXA1 GO:0051384| response to glucocorticoid stimulus PTGS2;HSD11B2;ANXA1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0043434| response to peptide hormone stimulus ANXA1;TRPV1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0046883| regulation of hormone secretion HTR1A;HTR2A;ANXA1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;ANXA1 GO:0070365| hepatocyte differentiation CYP1A1;ANXA1 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;CYP11B1;PTGS2 GO:0035865| cellular response to potassium ion CYP11B2;CYP11B1;CACNA1H;SOD1 GO:0098656| SLC22A8;VDAC1 GO:0006702| androgen biosynthetic process CYP17A1;HSD3B1 GO:0032868| response to insulin stimulus TRPV4;HSD11B2;CAT;AANAT GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0031394| positive regulation of prostaglandin biosynthetic process ANXA1;PTGS2 GO:0006811| ion transport TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;CACNA1H;TRPV3;SLCO1A2;GLRA3;SLC22A8 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;SLC22A8 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;ANXA1;TRPA1;CYP1A1;PPARG GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;CYP11B1;CYP11B2;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0050727| regulation of inflammatory response ANXA1;PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;ANXA1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0016125| sterol metabolic process CYP1B1;CYP17A1;CYP11B1;CYP11B2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0008152| metabolic process ACAT1;SMPD1;HSD3B1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;ANXA1;TRPV1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1 GO:0006954| inflammatory response IDO1;ALOX15;ANXA1;TRPV1;CNR2;PTGS2;PTGS1;ALOX5 GO:0034651| cortisol biosynthetic process CACNA1H;CYP11B1;CYP11B2 GO:0006955| immune response OPRD1;CYP11B1;CNR2 GO:0008209| androgen metabolic process CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;PTGS2 GO:0007565| female pregnancy IDO1;HSD11B2 GO:0046415| urate metabolic process ABCG2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C8;CYP2C19;CYP2C9 20613:[DB14011 DB07641] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;MAOA;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1 20614:[DB14011 DB01876] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01876|Bis(5-Amidino-2-Benzimidazolyl)Methanone PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 20615:[DB14011 DB04235] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT;CYP1A1;ABAT GO:0042220| response to cocaine CNR1;OPRM1;ABAT;SMPD1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;ABAT GO:0033602| negative regulation of dopamine secretion ABAT;CNR1 GO:0007626| locomotory behavior OPRM1;SOD1;ABAT GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;ABAT GO:0035094| response to nicotine CNR1;CHRNA7;ABAT GO:0035640| exploration behavior ABAT;HTR1A GO:0045776| negative regulation of blood pressure CNR1;ABAT GO:0045471| response to ethanol OPRM1;HMGCR;CNR1;SOD1;CAT;ABAT GO:0048148| behavioral response to cocaine ABAT;HTR2A 20616:[DB14011 DB00389] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways GO:0016125| sterol metabolic process CYP19A1;CYP17A1;CYP1B1 GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0022900| electron transport chain CYP19A1;GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALOX5;PTGS1;GPX1;CRYZ;TPO;CYP1A1;CYP2C9;CYP19A1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0006694| steroid biosynthetic process CYP17A1;CYP19A1;HMGCR GO:0098869| PTGS2;PTGS1;GPX1;CAT;TPO;GSR GO:0006979| response to oxidative stress TPO;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0042744| hydrogen peroxide catabolic process TPO;CAT;GPX1 GO:0042446| hormone biosynthetic process TPO;CYP17A1 20617:[DB14011 DB01164] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01164|Calcium Chloride S100A13 common genes common pathways GO:0046688| response to copper ion SOD1;S100A13;AANAT GO:0008284| positive regulation of cell proliferation CHRNA7;S100A13;HTR2A;HTR1A;HMGCR;PTGS2 20618:[DB14011 DB08703] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;MAP3K9 GO:0006915| apoptotic process VDAC1;GPX1;MAP3K9 GO:0008219| cell death MAP3K9;HTR2A GO:0006351| transcription, DNA-dependent MAP3K9;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;MAP3K9;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG 20619:[DB14011 DB04391] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04391|Aeruginosin 98-B PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20620:[DB14011 DB09283] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0042053| regulation of dopamine metabolic process PDE1B;HTR1A GO:0050896| response to stimulus PDE6A;TRPM8;PDE6C;PDE6B;TRPA1 GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0070588| calcium ion transmembrane transport TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;PDE2A;TRPA1;TRPV2;CHRNA7;CACNA1H;OPRM1;TRPV3 GO:0007165| signal transduction SMPD1;PDE2A;PDE5A;PDE8A;PDE3A;GPR18;PDE6B;PPARG;PDE1C;PLA2G1B;CACNA1I;PDE11A;PDE7A;PDE4C;PDE4B;PDE9A;PDE7B;PDE6C;PDE4A;OPRD1;PDE4D;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;PDE3B;PDE1B;PDE6A;CHRNA7;PDE1A;PDE10A;PDE8B GO:0001975| response to amphetamine PDE1B;CNR2;SOD1 GO:0050729| positive regulation of inflammatory response PDE2A;TRPV4 GO:0032869| cellular response to insulin stimulus PDE3B;PLA2G1B;PPARG GO:0043117| positive regulation of vascular permeability PDE2A;PDE3A;TRPV4 GO:0007601| visual perception PDE6B;GLRA1;CRYZ;GLRB;CYP1B1;PDE6C;PDE6A GO:0043951| negative regulation of cAMP-mediated signaling OPRM1;PDE3B GO:0008542| visual learning PDE1B;HMGCR GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0007268| synaptic transmission CACNA1G;GLRA1;VDAC1;GLRB;PDE7B;OPRD1;OPRM1;HTR2A;GLRA3 GO:0001934| positive regulation of protein phosphorylation PDE8A;CHRNA7 GO:0042428| serotonin metabolic process HTR1A;PDE1B GO:0008152| metabolic process PDE10A;ACAT1;PDE11A;PDE5A;SMPD1;PDE2A GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0071260| cellular response to mechanical stimulus PTGS2;PDE2A GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1;PPARG;CYP2C9;PDE3A;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B GO:0001525| angiogenesis PTGS2;PDE3B;CYP1B1 GO:0043406| positive regulation of MAP kinase activity HTR2A;PDE5A GO:0042130| negative regulation of T cell proliferation PDE5A;IDO1 GO:0051591| response to cAMP AANAT;PDE3A GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;PDE8A GO:0006915| apoptotic process PDE1B;GPX1;VDAC1 GO:0007186| G-protein coupled receptor signaling pathway PDE1A;PDE8B;PDE10A;PDE1B;PDE3B;GPR12;CNR1;HTR2A;GPR55;HTR1A;PDE4D;OPRD1;PDE4A;CNR2;OPRM1;PDE11A;PDE7A;PDE7B;PDE4C;PDE4B;GPR18;PPARG;PDE2A;PDE3A;PDE8A GO:0007568| aging CYP1A1;PTGS2;PDE4D;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1;PDE3B GO:0016525| negative regulation of angiogenesis PDE3B;PPARG GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B;PDE4B GO:0006355| regulation of transcription, DNA-dependent PPARG;PDE8A GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;PPARG;CYP1A1;TRPA1;PDE3A;SMPD1;ABCC1 GO:0030224| monocyte differentiation PDE2A;PPARG;PDE1B GO:0007626| locomotory behavior SOD1;OPRM1;PDE1B GO:0043066| negative regulation of apoptotic process PDE3A;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;PDE2A;TRPV1;TRPV4 20621:[DB14011 DB06941] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06941|(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide S100B common genes common pathways GO:0008283| cell proliferation HTR1A;GPX1;S100B;CYP1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;S100B GO:0007613| memory CHRNA7;S100B;HTR2A;CNR1;PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;S100B;CNR1;SOD1;PTGS2 GO:0071456| cellular response to hypoxia S100B;SLC29A1;OPRD1;PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;S100B;CHRNA7 GO:0045087| innate immune response S100B;PPARG GO:0007611| learning or memory S100B;CHRNA7;CNR1 20622:[DB14011 DB07268] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07268|2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE MAPK8 common genes common pathways GO:0048511| rhythmic process PPARG;MAPK8;AANAT GO:0010628| positive regulation of gene expression TRPV4;MAPK8 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;MAPK8;GPX1 GO:0051247| positive regulation of protein metabolic process MAPK8;CHRNA7 GO:0009411| response to UV MAPK8;CAT GO:0071276| cellular response to cadmium ion MAPK8;SOD1;CYP1A2 GO:0071260| cellular response to mechanical stimulus PTGS2;MAPK8 GO:0043065| positive regulation of apoptotic process MAPK8;PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0042752| regulation of circadian rhythm MAPK8;PPARG 20623:[DB14011 DB01482] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01482|Fenethylline CYP1A2 common genes CYP1A2 common pathways GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;PTGS2;CNR2 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CAT;GPX1;ALOX5;PTGS1 GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0010468| regulation of gene expression CYP1A2 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;TRPA1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG;NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0045333| cellular respiration CYP1A2 20624:[DB14011 DB01297] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01297|Practolol ADRB1;CYP2D6 common genes CYP2D6 common pathways GO:0051100| negative regulation of binding CYP2D6 GO:0050873| brown fat cell differentiation ADRB1;PTGS2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR;GPX1;NAAA;PTGS1;CYP2C9;PPARG;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0009409| response to cold TRPA1;PPARG;ADRB1;TRPM8 GO:0001659| temperature homeostasis TRPV1;ADRB1;HTR2A;GPX1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CACNA1I;ADRB1;PLA2G1B;SMPD1;PPARG;GPR18 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0002024| diet induced thermogenesis TRPV1;ADRB1;TRPV4 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1A1;CYP2C9 GO:0007186| G-protein coupled receptor signaling pathway ADRB1;GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 20625:[DB14011 DB11772] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11772|Pilaralisib PIK3CA common genes common pathways GO:0001889| liver development CYP1A1;ACAT1;PIK3CA GO:0001525| angiogenesis PIK3CA;PTGS2;CYP1B1 GO:0006954| inflammatory response ALOX5;PTGS1;PIK3CA;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0043524| negative regulation of neuron apoptosis SOD1;PIK3CA GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;PIK3CA GO:0014065| phosphatidylinositol 3-kinase cascade PIK3CA;HTR2A GO:0040014| regulation of multicellular organism growth SOD1;PIK3CA GO:0060612| adipose tissue development PIK3CA;ACAT1 GO:0045087| innate immune response PIK3CA;PPARG GO:0043542| endothelial cell migration PIK3CA;CYP1B1 GO:0071333| cellular response to glucose stimulus PIK3CA;SLC29A1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;PIK3CA GO:0060326| cell chemotaxis PIK3CA;ABCC1 GO:0010468| regulation of gene expression CYP1A2;PIK3CA GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PIK3CA 20626:[DB14011 DB14067] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1;ABCB5 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1;ABCB5 GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G;ABCB5;TRPV2;TRPV3;CACNA1H GO:0006810| transport ABCC1;ABCG2;ABCB1;CACNA1I;TRPV1;TRPV2 GO:0042391| regulation of membrane potential CACNA1H;ABCB5;CACNA1G;GLRA1;GLRB GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCB1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT 20627:[DB14011 DB02095] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02095|Isatin MAOB;MAOB common genes common pathways GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;MAOB;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;MAOB;ABCG2 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;MAOB GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MAOB;CNR1;OPRM1;CYP1A2;PTGS2;CNR2 GO:0010269| response to selenium ion MAOB;GPX1 GO:0009636| response to toxin CAT;GPX1;CYP1A1;MAOB;CYP1B1 GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;MAOB 20628:[DB14011 DB09568] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes CYP3A4;CYP3A5;CYP3A7 common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0008152| metabolic process ECHS1;SMPD1;ACAT1 GO:0009409| response to cold PPARG;TRPA1;LPL;TRPM8 GO:0006629| lipid metabolic process DGAT2;CYP2C9;PPARG;TRPV1;PLA2G1B;LPL;ALOX15;ELOVL4;CYP2D6;ECHS1;DAGLA;PTGS2;CYP1A2;HMGCR;HADH;NAPEPLD;CYP3A4;HSD17B10;NAAA;GPX1;PTGS1 GO:0042572| retinol metabolic process DGAT2;CYP1B1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0051289| protein homotetramerization TRPM8;TRPV1;CRYZ;TRPA1;CAT;HSD17B10 GO:0050729| positive regulation of inflammatory response TRPV4;LPL GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP3A4 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP4F2;CYP1B1;CYP2C19 GO:0006633| fatty acid biosynthetic process ELOVL4;LPL;PLA2G1B;PTGS1;PTGS2 GO:0009725| response to hormone stimulus HADH;ACAT1 GO:0006641| triglyceride metabolic process GPX1;CAT;LPL GO:0032868| response to insulin stimulus TRPV4;HADH;AANAT;CAT GO:0001523| retinoid metabolic process LPL;NAPEPLD GO:0014823| response to activity HADH;CAT GO:0008217| regulation of blood pressure PPARG;CYP4F2;PTGS2;SOD1;PTGS1 GO:0006635| fatty acid beta-oxidation ACAT1;HADH;ECHS1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP4F2;CYP2C19;CYP1A2 GO:0006691| leukotriene metabolic process ALOX5;ALOX15;CYP4F2;ABCC1 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HADH;SOD1;HTR2A;LPL;ABCG2;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;HADH;ECHS1;ELOVL4;ALOX15 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP4F2;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;HADH;CYP3A4;SOD1;HSD17B10;ALOX5;GPX1;PTGS1;CYP3A43;CAT GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP4F2;CYP1B1;FAAH GO:0009083| branched chain family amino acid catabolic process ACAT1;HSD17B10 GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP4F2;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0016042| lipid catabolic process DAGLA;LPL;PLA2G1B;NAPEPLD GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0006644| phospholipid metabolic process PLA2G1B;LPL;NAPEPLD 20629:[DB14011 DB02249] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02249|2-Ethoxyethanol ADH1C common genes common pathways GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;ADH1C;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP2C9;CYP1A1;CRYZ 20630:[DB14011 DB00491] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways GO:0008152| metabolic process GANAB;GAA;ACAT1;AMY2A;MGAM;SMPD1;GANC GO:0050884| neuromuscular process controlling posture GAA;GLRA1 GO:0043312| neutrophil degranulation CAT;MGAM;ALOX5;GAA GO:0007626| locomotory behavior SOD1;GAA;OPRM1 GO:0046716| muscle cell homeostasis GAA;SOD1 20631:[DB14011 DB04556] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development ACHE;SMPD1;GLRB GO:0008283| cell proliferation GPX1;HTR1A;ACHE;CYP1A1 GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development CACNA1H;ACHE GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE 20632:[DB14011 DB07368] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07368|4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20633:[DB14011 DB09008] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0006811| ion transport GLRA3;SLC22A8;CACNA1H;TRPV3;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1 GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0055085| transmembrane transport SLC22A8;CACNA1H;TRPV3;TRPV2;TRPA1;SLC22A6;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 20634:[DB14011 DB06436] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06436|Semaxanib KDR;PTGS2 common genes PTGS2 common pathways GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;CYP1B1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0033280| response to vitamin D PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0016032| viral reproduction HTR2A;VDAC1;KDR GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;IDO1;ALOX15;TRPV1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0010629| negative regulation of gene expression OPRD1;KDR GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;OPRM1;CNR2;PTGS2;TRPV1;TRPA1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1;KDR GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;KDR GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;ALOX15;TRPV4;KDR GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0007568| aging CYP1A1;CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV4;TRPV1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0009750| response to fructose stimulus PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;KDR GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;KDR GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2;VDAC1 20635:[DB14011 DB04970] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04970|Lesopitron HTR1A common genes HTR1A common pathways GO:0042053| regulation of dopamine metabolic process HTR1A GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0001662| behavioral fear response HTR1A;VDAC1 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0007610| behavior HTR2A;HTR1A GO:0042428| serotonin metabolic process HTR1A GO:0042310| vasoconstriction HTR1A GO:0014062| regulation of serotonin secretion HTR1A GO:0007210| serotonin receptor signaling pathway HTR1A;HTR2A GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0035640| exploration behavior HTR1A GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0050795| regulation of behavior HTR2A;HTR1A 20636:[DB14011 DB08546] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08546|4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 20637:[DB14011 DB00335] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes CYP2D6 common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;ADRB1;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;ADRB2 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP2C9;CYP1A1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0006810| transport ABCG2;TRPV1;ABCB1;CACNA1I;ABCC1;TRPV2;ABCB11 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;CACNA1I;ABCB1;TRPV4;TRPV1;TRPA1;ABCC1;CACNA1G;TRPV2;ABCB11;TRPV3;CACNA1H GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0002024| diet induced thermogenesis TRPV1;ADRB1;TRPV4;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;PLA2G1B;PPARG GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCB1;ABCG2 GO:0055114| oxidation-reduction process CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1;ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0019369| arachidonic acid metabolic process CYP1B1;DAGLA;CYP2D6;ALOX15;FAAH GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0043950| positive regulation of cAMP-mediated signaling OPRM1;ADRB1 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0045453| bone resorption GPR55;ADRB2 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0007165| signal transduction PLA2G1B;ADRB1;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;ADRB2 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0050873| brown fat cell differentiation ADRB1;ADRB2;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;ADRB2 GO:0051100| negative regulation of binding CYP2D6 GO:0035725| sodium ion transmembrane transport ABCB11;CACNA1H;CACNA1I;CACNA1G GO:0001659| temperature homeostasis TRPV1;ADRB1;GPX1;HTR2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;ADRB2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0009409| response to cold TRPM8;ADRB1;PPARG;TRPA1;ADRB2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG;PTGS1;NAAA;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4 20638:[DB14011 DB06867] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways GO:0043524| negative regulation of neuron apoptosis PIN1;SOD1 GO:0001934| positive regulation of protein phosphorylation PIN1;CHRNA7 GO:0050808| synapse organization CHRNA7;PIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PIN1;PPARG GO:0035307| positive regulation of protein dephosphorylation PIN1;SMPD1 20639:[DB14011 DB07412] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;DPP4;CYP1A1 GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4 20640:[DB14011 DB02710] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02710|2,3,-Dihydroxybenzoylserine LCN2 common genes common pathways GO:0002376| immune system process IDO1;LCN2 GO:0006915| apoptotic process GPX1;LCN2;VDAC1 GO:0043312| neutrophil degranulation LCN2;ALOX5;CAT GO:0045087| innate immune response LCN2;PPARG GO:0006811| ion transport TRPV2;LCN2;CHRNA7;CACNA1H;TRPV3;GLRA3;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:0006879| cellular iron ion homeostasis LCN2;SOD1;ABCG2 20641:[DB14011 DB01681] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways GO:0007283| spermatogenesis SOD1;CNR1;PGAM2 GO:0008152| metabolic process PGAM2;SMPD1;ACAT1 20642:[DB14011 DB08492] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes ALOX15 common pathways GO:0001503| ossification ALOX15 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1 GO:0035358| regulation of peroxisome proliferator activated receptor signaling pathway ALOX15 GO:0071277| cellular response to calcium ion ALOX15 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;IDO1;ALOX15;TRPV1 GO:0010811| positive regulation of cell-substrate adhesion ALOX15 GO:0035963| cellular response to interleukin-13 ALOX15 GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15 GO:0051122| hepoxilin biosynthetic process ALOX15 GO:0034976| response to endoplasmic reticulum stress ALOX15 GO:0042060| wound healing OPRM1;ALOX15 GO:0030838| positive regulation of actin filament polymerization ALOX15 GO:0019369| arachidonic acid metabolic process DAGLA;CYP2D6;ALOX15;CYP1B1;FAAH GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0006691| leukotriene metabolic process ALOX5;ALOX15;ABCC1 GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0002820| negative regulation of adaptive immune response ALOX15 GO:2001303| ALOX15 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0006646| phosphatidylethanolamine biosynthetic process ALOX15 GO:0043277| apoptotic cell clearance ALOX15 GO:1901074| ALOX15 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 20643:[DB14011 DB02504] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02504|[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid PLA2G2A common genes common pathways GO:0006644| phospholipid metabolic process PLA2G2A;PLA2G1B;NAPEPLD GO:0016042| lipid catabolic process PLA2G1B;DAGLA;PLA2G2A;NAPEPLD GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;PLA2G2A;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0036152| PLA2G1B;PLA2G2A GO:0050830| defense response to Gram-positive bacterium PLA2G1B;PLA2G2A GO:0006654| phosphatidic acid biosynthetic process PLA2G2A;PLA2G1B GO:0036151| PLA2G1B;PLA2G2A GO:0036150| PLA2G2A;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2A GO:0050729| positive regulation of inflammatory response PLA2G2A;TRPV4 GO:0036148| PLA2G2A;PLA2G1B GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;PLA2G2A;ALOX15;CYP2C9;PPARG;PTGS1;NAAA;GPX1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4 GO:0036149| PLA2G1B;PLA2G2A 20644:[DB14011 DB07076] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07076|6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE PLAU common genes common pathways GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PLAU;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLAU GO:0043312| neutrophil degranulation ALOX5;CAT;PLAU GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;PLAU 20645:[DB14011 DB00015] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0061045| negative regulation of wound healing HMGCR;SERPINE1 GO:0001525| angiogenesis CYP1B1;PTGS2;SERPINE1 GO:0051592| response to calcium ion AANAT;FGA GO:0001934| positive regulation of protein phosphorylation PLAUR;CHRNA7 GO:0045907| positive regulation of vasoconstriction FGA;HTR2A;PTGS2 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;PLAUR;FGA GO:0034116| positive regulation of heterotypic cell-cell adhesion FGA;ALOX15 GO:0050729| positive regulation of inflammatory response TRPV4;SERPINE1 GO:0030336| negative regulation of cell migration SERPINE1;CYP1B1 GO:1902042| GPX1;SERPINE1;FGA GO:0008285| negative regulation of cell proliferation PLG;PPARG;CYP1B1;OPRM1;PTGS2 GO:0002576| platelet degranulation FGA;PLG;SERPINE1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;SERPINE1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;PLAUR GO:0045087| innate immune response FGA;PPARG GO:0043312| neutrophil degranulation PLAUR;ALOX5;CAT GO:0007623| circadian rhythm AANAT;SERPINE1 GO:0033629| negative regulation of cell adhesion mediated by integrin SERPINE1;CYP1B1 GO:0051702| interaction with symbiont GPX1;PLG GO:0002376| immune system process FGA;IDO1 GO:0043388| positive regulation of DNA binding PLAUR;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade FGA;TRPV4;ALOX15;HMGCR;OPRM1;HTR2A;GPR55;CHRNA7 GO:0050714| positive regulation of protein secretion FGA;PLA2G1B GO:0045766| positive regulation of angiogenesis CHRNA7;SERPINE1;CYP1B1 20646:[DB14011 DB08651] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways 20647:[DB14011 DB07271] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0007155| cell adhesion CYP1B1;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;DPP4 GO:0046718| entry of virus into host cell DPP4;HTR2A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0001662| behavioral fear response VDAC1;DPP4;HTR1A 20648:[DB14011 DB06856] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06856|6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE PLAU common genes common pathways GO:0007165| signal transduction PLAU;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLAU GO:0001666| response to hypoxia CYP1A1;PLAU;CAT;CHRNA7 20649:[DB14011 DB04612] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04612|N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process CAT;GPX1;XIAP;SOD1;HMGCR;PTGS2 GO:0042127| regulation of cell proliferation XIAP;PTGS2;PTGS1 GO:0006915| apoptotic process GPX1;XIAP;VDAC1 GO:0050727| regulation of inflammatory response PTGS2;XIAP GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;XIAP;GPX1 20650:[DB14011 DB03181] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways GO:0008016| regulation of heart contraction THRB;CACNA1H GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;THRB GO:0006351| transcription, DNA-dependent THRB;PPARG GO:0043401| steroid hormone mediated signaling pathway THRB;PPARG GO:0006355| regulation of transcription, DNA-dependent THRB;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;THRB;TRPV1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;THRB GO:0007605| sensory perception of sound THRB;GPX1;SOD1 20651:[DB14011 DB09302] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09302|Alirocumab PCSK9 common genes common pathways GO:0001822| kidney development PCSK9;CAT GO:0008203| cholesterol metabolic process PCSK9;HMGCR;CAT GO:0043523| regulation of neuron apoptosis PCSK9;GPX1 GO:0006644| phospholipid metabolic process PLA2G1B;PCSK9;NAPEPLD GO:0006915| apoptotic process VDAC1;GPX1;PCSK9 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;PCSK9;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0006629| lipid metabolic process DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;PCSK9;CYP1A2;PTGS2 GO:0001889| liver development ACAT1;PCSK9;CYP1A1 GO:0006641| triglyceride metabolic process GPX1;CAT;PCSK9 GO:0032869| cellular response to insulin stimulus PCSK9;PLA2G1B;PPARG GO:0022008| neurogenesis DAGLA;PCSK9 20652:[DB14011 DB03906] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0008285| negative regulation of cell proliferation HMOX1;PTGS2;OPRM1;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PTGS2;HMOX1;SOD1;PTGS1;PPARG GO:0043627| response to estrogen stimulus HMOX1;PPARG GO:1902042| GPX1;HMOX1 GO:0071276| cellular response to cadmium ion CYP1A2;HMOX1;SOD1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;HMOX1 GO:0006879| cellular iron ion homeostasis ABCG2;HMOX1;SOD1 GO:1904706| PPARG;HMOX1 GO:0043524| negative regulation of neuron apoptosis HMOX1;SOD1 GO:0035556| intracellular signal transduction HMOX1;PLA2G1B GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;HMOX1;CNR1;SOD1;PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;HMOX1;SOD1;GPX1;CAT GO:0001525| angiogenesis CYP1B1;HMOX1;PTGS2 GO:0001666| response to hypoxia HMOX1;CHRNA7;CAT;CYP1A1 GO:0006915| apoptotic process VDAC1;HMOX1;GPX1 GO:0008219| cell death HTR2A;HMOX1 GO:0045766| positive regulation of angiogenesis HMOX1;CHRNA7;CYP1B1 GO:0006979| response to oxidative stress PTGS2;HMOX1;SOD1;GPX1;PTGS1;CAT GO:0051260| protein homooligomerization ACAT1;GLRA3;HMOX1;GLRA1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;HMOX1;SLC29A1 GO:0034605| cellular response to heat PTGS2;HMOX1;TRPV4;TRPV1 GO:0035094| response to nicotine HMOX1;CNR1;CHRNA7 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2;HMGCR GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1;ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;HMOX1 20653:[DB14011 DB13044] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13044|Gossypol BCL2L1 common genes common pathways GO:0007283| spermatogenesis BCL2L1;CNR1;SOD1 GO:0001541| ovarian follicle development SOD1;BCL2L1 GO:0006915| apoptotic process GPX1;BCL2L1;VDAC1 GO:0034097| response to cytokine stimulus BCL2L1;PTGS2;AANAT GO:0008284| positive regulation of cell proliferation BCL2L1;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0009615| response to virus CYP1A1;BCL2L1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;BCL2L1 GO:0071230| cellular response to amino acid stimulus BCL2L1;GLRA1 GO:1902042| BCL2L1;GPX1 GO:0051881| regulation of mitochondrial membrane potential BCL2L1;SOD1;OPRD1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;BCL2L1 GO:0090201| negative regulation of release of cytochrome c from mitochondria BCL2L1;GPX1 GO:0043524| negative regulation of neuron apoptosis SOD1;BCL2L1 GO:0009314| response to radiation OPRM1;PTGS2;CAT;BCL2L1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1;BCL2L1 GO:0071312| cellular response to alkaloid TRPV1;BCL2L1 20654:[DB14011 DB12789] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12789|Dinoprost PTGDR2 common genes common pathways GO:0007218| neuropeptide signaling pathway GLRA3;OPRM1;OPRD1;PTGDR2;GLRA1;GLRB GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGDR2;CNR2;OPRM1;OPRD1;CNR1 GO:0007186| G-protein coupled receptor signaling pathway PTGDR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;GLRA3;HTR2A;OPRM1;OPRD1;PTGDR2 GO:0006955| immune response OPRD1;CNR2;PTGDR2 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;PTGDR2 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;PTGDR2;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 20655:[DB14011 DB08321] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08321|(1S,2S,3R,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol MAN2A1 common genes common pathways GO:0050769| positive regulation of neurogenesis MAN2A1;OPRM1 GO:0001889| liver development ACAT1;MAN2A1;CYP1A1 GO:0008152| metabolic process MAN2A1;SMPD1;ACAT1 20656:[DB14011 DB01852] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01852|Kaempherol UGT3A1 common genes common pathways GO:0008152| metabolic process ACAT1;SMPD1;UGT3A1 20657:[DB14011 DB02235] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02235|L-methionine (R)-S-oxide APP common genes common pathways GO:0000187| activation of MAPK activity PLA2G1B;APP;CHRNA7;SOD1 GO:0006915| apoptotic process GPX1;VDAC1;APP GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;TRPV4;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0051262| protein tetramerization APP;CAT;HMGCR GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0010468| regulation of gene expression CYP1A2;APP GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;APP;GPR18;PPARG GO:0098815| APP;CHRNA7 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;APP;TRPV1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;APP GO:0051260| protein homooligomerization APP;GLRA1;ACAT1;GLRA3 GO:0019731| antibacterial humoral response PLA2G1B;APP GO:0050808| synapse organization CHRNA7;APP GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0051247| positive regulation of protein metabolic process CHRNA7;APP GO:0051897| positive regulation of protein kinase B signaling cascade APP;GPX1 GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:1905906| APP;CHRNA7 GO:0007611| learning or memory APP;CHRNA7;CNR1 GO:0008203| cholesterol metabolic process APP;HMGCR;CAT GO:0007612| learning PTGS2;APP;VDAC1 GO:0010288| response to lead ion CAT;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;APP;TRPV4;TRPV1 GO:0045087| innate immune response PPARG;APP GO:0007155| cell adhesion APP;CYP1B1 GO:0002576| platelet degranulation APP;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;PPARG;PLA2G1B GO:0007626| locomotory behavior APP;SOD1;OPRM1 GO:0008344| adult locomotory behavior OPRD1;APP GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;APP;PPARG GO:0061844| PLA2G1B;APP GO:0032930| positive regulation of superoxide anion generation APP;SOD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;APP GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7;APP GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;APP;HTR2A;OPRM1 GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2;OPRD1 GO:1900273| CHRNA7;APP GO:1902004| APP;CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:0007268| synaptic transmission VDAC1;GLRB;CACNA1G;APP;GLRA1;OPRM1;OPRD1;HTR2A;GLRA3 GO:0010629| negative regulation of gene expression OPRD1;APP GO:0071320| cellular response to cAMP AANAT;APP GO:0008542| visual learning APP;HMGCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;APP;CAT GO:0001774| microglial cell activation APP;TRPV1 GO:1990090| TRPV1;APP GO:0007399| nervous system development APP;SMPD1;GLRB GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;APP;SMPD1;IDO1;TRPV1;CYP1B1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP 20658:[DB14011 DB05147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05147|CYT997 TUBA1A;TUBA1B;TUBA1C;TUBA4A;TUBA3C;TUBA3E;TUBA4B;TUBB1;TUBB2A;TUBB2B;TUBB4B;TUBB3;TUBB4A;TUBB;TUBB6 common genes common pathways GO:0007399| nervous system development SMPD1;TUBB2B;GLRB GO:0002576| platelet degranulation TUBA4A;SOD1 GO:0043312| neutrophil degranulation TUBB;TUBB4B;CAT;ALOX5 20659:[DB14011 DB03551] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways GO:0042493| response to drug SMPD1;ABCC1;PNP;CYP1A1;PPARG;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0043312| neutrophil degranulation PNP;CAT;ALOX5 GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0006955| immune response PNP;CNR2;OPRD1 20660:[DB14011 DB04043] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04043|Carboxymycobactin T LCN2 common genes common pathways GO:0045087| innate immune response LCN2;PPARG GO:0043312| neutrophil degranulation CAT;ALOX5;LCN2 GO:0006915| apoptotic process VDAC1;LCN2;GPX1 GO:0002376| immune system process LCN2;IDO1 GO:0006879| cellular iron ion homeostasis LCN2;SOD1;ABCG2 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;LCN2;CHRNA7;CACNA1G;GLRA1;TRPA1;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8 20661:[DB14011 DB05073] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05073|SRT501 SIRT1 common genes common pathways GO:0050872| white fat cell differentiation PPARG;SIRT1 GO:0016032| viral reproduction HTR2A;SIRT1;VDAC1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;SIRT1 GO:0010629| negative regulation of gene expression OPRD1;SIRT1 GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;SIRT1;TRPA1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1;SIRT1 GO:0001525| angiogenesis PTGS2;SIRT1;CYP1B1 GO:0006351| transcription, DNA-dependent PPARG;SIRT1 GO:0035358| regulation of peroxisome proliferator activated receptor signaling pathway ALOX15;SIRT1 GO:0070301| cellular response to hydrogen peroxide CYP1B1;SIRT1 GO:0032868| response to insulin stimulus CAT;AANAT;TRPV4;SIRT1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1;SIRT1 GO:1902176| GPX1;SIRT1 GO:0007569| cell aging SOD1;SIRT1 GO:0006355| regulation of transcription, DNA-dependent SIRT1;PPARG GO:0007517| muscle organ development CACNA1H;SIRT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;SIRT1;TRPV1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter SIRT1;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation SIRT1;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;SIRT1 GO:0007623| circadian rhythm SIRT1;AANAT GO:0042127| regulation of cell proliferation PTGS1;PTGS2;SIRT1 GO:0030308| negative regulation of cell growth SIRT1;PPARG GO:0071356| cellular response to tumor necrosis factor SIRT1;TRPV1 GO:0048511| rhythmic process PPARG;SIRT1;AANAT GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SIRT1 GO:0007283| spermatogenesis SIRT1;CNR1;SOD1 GO:0045766| positive regulation of angiogenesis CHRNA7;SIRT1;CYP1B1 GO:0006915| apoptotic process VDAC1;SIRT1;GPX1 GO:0006979| response to oxidative stress SIRT1;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0071456| cellular response to hypoxia SIRT1;SLC29A1;PTGS2;OPRD1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;SIRT1 20662:[DB14011 DB07950] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07950|Indoleacetic acid PLA2G2E;SKP1;CCBL1 common genes common pathways GO:0036152| PLA2G2E;PLA2G1B GO:0016042| lipid catabolic process NAPEPLD;DAGLA;PLA2G2E;PLA2G1B GO:0006644| phospholipid metabolic process PLA2G1B;PLA2G2E;NAPEPLD GO:0036151| PLA2G2E;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2E GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2E GO:0036150| PLA2G2E;PLA2G1B GO:0036149| PLA2G2E;PLA2G1B GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G2E;TRPV1;PLA2G1B GO:0036148| PLA2G2E;PLA2G1B GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;SKP1 GO:0006954| inflammatory response PLA2G2E;TRPV1;IDO1;ALOX15;PTGS2;CNR2;PTGS1;ALOX5 20663:[DB14011 DB05010] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GABBR2;PPARG;GPR18;GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;GABBR1;OPRM1;OPRD1 GO:0007165| signal transduction PLA2G1B;CACNA1I;GABBR2;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;GABBR1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;GABBR1;OPRD1 GO:0007194| negative regulation of adenylate cyclase activity GABBR1;OPRM1;GABBR2 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRM1;OPRD1;GABBR2;GLRB;VDAC1;GLRA1;CACNA1G 20664:[DB14011 DB05374] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05374|Rindopepimut EGFR common genes common pathways GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response EGFR;TRPV4 GO:0007165| signal transduction GPR18;PPARG;SMPD1;EGFR;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;OPRD1;PTGS2 GO:0045907| positive regulation of vasoconstriction EGFR;HTR2A;PTGS2 GO:0008283| cell proliferation GPX1;HTR1A;EGFR;CYP1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;EGFR;PTGS2;CYP1A2;ACAT1;AANAT GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0007166| cell surface receptor linked signaling pathway EGFR;TRPV1;TRPA1 GO:0001889| liver development ACAT1;CYP1A1;EGFR GO:0051592| response to calcium ion EGFR;AANAT GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0001503| ossification ALOX15;EGFR GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0035556| intracellular signal transduction PLA2G1B;EGFR GO:0001934| positive regulation of protein phosphorylation CHRNA7;EGFR GO:0071363| cellular response to growth factor stimulus EGFR;TRPV1;CAT;OPRD1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT;EGFR GO:0033993| response to lipid PPARG;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;EGFR;PTGS2;OPRM1 GO:0006979| response to oxidative stress EGFR;PTGS2;SOD1;GPX1;PTGS1;CAT GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;EGFR;ALOX15 GO:0043406| positive regulation of MAP kinase activity HTR2A;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0007202| activation of phospholipase C activity EGFR;GPR55;HTR2A GO:0071230| cellular response to amino acid stimulus GLRA1;EGFR GO:0030324| lung development CYP1A2;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS1;PTGS2 GO:0042060| wound healing EGFR;ALOX15;OPRM1 GO:0007623| circadian rhythm EGFR;AANAT GO:0007611| learning or memory CNR1;CHRNA7;EGFR GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;EGFR;PLA2G1B GO:0043066| negative regulation of apoptotic process EGFR;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;EGFR 20665:[DB14011 DB00089] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00089|Capromab pendetide FOLH1 common genes common pathways GO:0008152| metabolic process ACAT1;FOLH1;SMPD1 20666:[DB14011 DB04583] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT;DHODH GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;DHODH;ALOX5;PTGS1;GPX1;CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1 GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0031000| response to caffeine DHODH;PPARG GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy DHODH;IDO1 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;DHODH;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;AANAT;ACAT1;DHODH;CYP1A2;PTGS2 20667:[DB14011 DB04851] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04851|Biricodar dicitrate ABCB5;ABCC1;ABCG2 common genes ABCG2;ABCC1 common pathways GO:0046415| urate metabolic process ABCG2 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB5 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0042908| xenobiotic transport ABCB5;ABCC1;ABCG2 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0099133| ABCC1 GO:0015886| heme transport ABCG2 GO:0060326| cell chemotaxis ABCC1 GO:0033344| cholesterol efflux ABCG2 GO:0055085| transmembrane transport TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;CACNA1H;TRPV3;ABCB5;TRPV2 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCG2;TRPV2 GO:0042391| regulation of membrane potential GLRB;CACNA1G;GLRA1;ABCB5;CACNA1H 20668:[DB14011 DB01675] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;ACAD8 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;ACAD8 GO:0006351| transcription, DNA-dependent ACAD8;PPARG GO:0009083| branched chain family amino acid catabolic process ACAT1;ACAD8 GO:0006355| regulation of transcription, DNA-dependent ACAD8;PPARG GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;ACAD8;CAT;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1 20669:[DB14011 DB09326] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09326|Ammonia N-13 NAGS;RHCG common genes common pathways GO:0030855| epithelial cell differentiation RHCG;VDAC1;PPARG 20670:[DB14011 DB00894] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00894|Testolactone CYP19A1 common genes common pathways GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP19A1 GO:0008209| androgen metabolic process CYP3A4;CYP19A1 GO:0022900| electron transport chain CYP19A1;GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;ALOX5;PTGS1;GPX1;CRYZ;CYP2C9;CYP1A1;CYP19A1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;CYP19A1 20671:[DB14011 DB07457] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways GO:0032869| cellular response to insulin stimulus PLA2G1B;PDPK1;PPARG GO:0006351| transcription, DNA-dependent PDPK1;PPARG GO:0035556| intracellular signal transduction PLA2G1B;PDPK1 GO:0043524| negative regulation of neuron apoptosis SOD1;PDPK1 GO:0045766| positive regulation of angiogenesis CYP1B1;PDPK1;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1 20672:[DB14011 DB07970] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways GO:0006915| apoptotic process GPX1;EPHA7;VDAC1 GO:0001934| positive regulation of protein phosphorylation EPHA7;CHRNA7 GO:0007399| nervous system development GLRB;EPHA7;SMPD1 GO:0043065| positive regulation of apoptotic process SMPD1;EPHA7;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0007420| brain development EPHA7;ACAT1 20673:[DB14011 DB07844] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07844|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 20674:[DB14011 DB07051] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;PDE4D;GPR55;HTR1A;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B GO:0007568| aging CYP1A1;CAT;HMGCR;PDE4D;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;PDE4D;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A 20675:[DB14011 DB08207] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways GO:0043312| neutrophil degranulation ALOX5;TTR;CAT GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;TTR;TRPV2 GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0001523| retinoid metabolic process NAPEPLD;TTR 20676:[DB14011 DB02924] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02924|(4R)-limonene 1α,2α-epoxide LCN9 common genes common pathways 20677:[DB14011 DB00086] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00086|Streptokinase PLG;F2R;PLA2G4A common genes common pathways GO:0051930| regulation of sensory perception of pain F2R;OPRM1;OPRD1 GO:0009395| phospholipid catabolic process NAPEPLD;PLA2G4A GO:0006919| activation of caspase activity PPARG;F2R GO:0045987| positive regulation of smooth muscle contraction PTGS2;F2R GO:0036150| PLA2G1B;PLA2G4A GO:0008285| negative regulation of cell proliferation CYP1B1;PLG;PPARG;PTGS2;OPRM1;F2R GO:0007204| elevation of cytosolic calcium ion concentration F2R;HTR2A;OPRM1;TRPV4;TRPV1 GO:0099553| F2R;CNR1 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;F2R GO:0050482| arachidonic acid secretion PLA2G4A;PLA2G1B GO:0007165| signal transduction CHRNA7;HTR1A;F2R;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0043524| negative regulation of neuron apoptosis SOD1;F2R GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;PTGS2;CNR2;F2R GO:2000778| positive regulation of interleukin-6 secretion TRPV4;F2R GO:0036149| PLA2G1B;PLA2G4A GO:0008152| metabolic process PLA2G4A;SMPD1;ACAT1 GO:0036148| PLA2G1B;PLA2G4A GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PLA2G4A;CYP2C9;PPARG;NAAA;PTGS1;GPX1;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4 GO:0016042| lipid catabolic process NAPEPLD;PLA2G4A;PLA2G1B;DAGLA GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;F2R;GPR55;HTR2A;CHRNA7;TRPV4;ALOX15 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR18;GPR55;F2R GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G4A;PLA2G1B GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;HTR1A;F2R;GPR55;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0009611| response to wounding GPX1;F2R;CYP1A1 GO:0051209| release of sequestered calcium ion into cytosol F2R;HTR2A;TRPA1;TRPV1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2R;CAT GO:0035025| positive regulation of Rho protein signal transduction F2R;GPR55;GPR18 GO:0036152| PLA2G4A;PLA2G1B GO:0045893| positive regulation of transcription, DNA-dependent F2R;PPARG GO:0051702| interaction with symbiont GPX1;PLG GO:0019369| arachidonic acid metabolic process FAAH;PLA2G4A;ALOX15;DAGLA;CYP2D6;CYP1B1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;F2R;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0042127| regulation of cell proliferation PLA2G4A;PTGS2;PTGS1 GO:0036151| PLA2G1B;PLA2G4A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger F2R;HTR2A;OPRM1;OPRD1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;F2R;CHRNA7 GO:0002576| platelet degranulation PLG;SOD1 GO:0006654| phosphatidic acid biosynthetic process PLA2G4A;PLA2G1B 20678:[DB14011 DB13995] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13995|Ferric pyrophosphate citrate FTL;FTH1;HBA1;HBB common genes common pathways GO:0098869| HBB;HBA1;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HBB GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;HBA1;HBB GO:0043312| neutrophil degranulation CAT;FTL;ALOX5;FTH1;HBB GO:0055114| oxidation-reduction process FTH1;GPX1;ALOX5;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP2C9;CYP1A1;CRYZ GO:0051291| protein heterooligomerization GLRA1;HBB;HBA1;GLRB GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;HBB GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;FTH1 GO:0042542| response to hydrogen peroxide SOD1;GPX1;CAT;HBA1;TRPA1;HBB GO:0010942| positive regulation of cell death HBA1;HBB;PTGS2 GO:0006955| immune response FTH1;OPRD1;CNR2 GO:0006879| cellular iron ion homeostasis FTL;FTH1;SOD1;ABCG2 20679:[DB14011 DB11572] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11572|Thrombin Alfa F11;F8;F5;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0002576| platelet degranulation FGA;F5;F13A1;FGG;F8;FGB;SOD1 GO:0045087| innate immune response FGB;FGA;PPARG GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;F8;CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1 GO:0002376| immune system process IDO1;FGA;FGB GO:0050714| positive regulation of protein secretion FGB;FGA;PLA2G1B;FGG GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;FGB;CHRNA7;FGG;TRPV4;FGA;ALOX15 GO:0051592| response to calcium ion FGG;FGA;AANAT;FGB GO:0045907| positive regulation of vasoconstriction FGB;PTGS2;HTR2A;FGA;FGG GO:0007165| signal transduction CHRNA7;FGB;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;FGA;PPARG;GPR18;SMPD1;FGG GO:0034116| positive regulation of heterotypic cell-cell adhesion FGB;FGA;ALOX15;FGG GO:1902042| FGB;GPX1;FGA;FGG 20680:[DB14011 DB06795] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06795|Mafenide CA6 common genes common pathways 20681:[DB14011 DB00447] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport TRPV2;SLC15A2;CACNA1H;TRPV3;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;SLC15A1;CACNA1G;ABCC1 GO:0006810| transport SLC15A2;TRPV2;ABCC1;SLC15A1;TRPV1;CACNA1I;ABCG2 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;SLC15A1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8;TRPV3;CACNA1H;GLRA3;SLC15A2;TRPV2;CHRNA7 20682:[DB14011 DB05854] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05854|CLX-0921 PPARG common genes PPARG common pathways GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0030308| negative regulation of cell growth PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0032526| response to retinoic acid PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0015909| long-chain fatty acid transport PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;GPX1;NAAA;PTGS1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0042953| lipoprotein transport PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0048469| cell maturation PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1904706| PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG GO:1905461| PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0060694| regulation of cholesterol transporter activity PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;PPARG GO:0055088| lipid homeostasis PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 20683:[DB14011 DB00492] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure PPARG;ACE;PTGS1;SOD1;PTGS2 GO:0006811| ion transport SLC15A2;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;SLC15A1;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0060047| heart contraction SOD1;GPX1;ACE GO:0007283| spermatogenesis ACE;CNR1;SOD1 GO:0055085| transmembrane transport TRPV2;SLC15A2;CACNA1H;TRPV3;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;SLC15A1;CACNA1G;ABCC1 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;SLC15A1;TRPV2;SLC15A2 GO:0001822| kidney development ACE;CAT 20684:[DB14011 DB03213] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03213|Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 20685:[DB14011 DB05443] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRK1;OPRM1;OPRD1 GO:0050951| sensory perception of temperature stimulus TRPM8;OPRK1 GO:0007165| signal transduction CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;OPRK1;PLA2G1B;CACNA1I GO:0007610| behavior OPRK1;HTR2A;HTR1A GO:0044849| OPRM1;OPRK1 GO:0032868| response to insulin stimulus TRPV4;OPRK1;AANAT;CAT GO:0042755| eating behavior OPRD1;OPRM1;OPRK1 GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OPRK1 GO:0043627| response to estrogen stimulus OPRK1;PPARG GO:0019233| sensory perception of pain CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1;TRPA1;OPRK1;TRPV1 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;OPRK1 GO:0048148| behavioral response to cocaine OPRK1;HTR2A GO:0009314| response to radiation OPRM1;PTGS2;CAT;OPRK1 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;GLRA3;GLRB;VDAC1;OPRK1;CACNA1G;GLRA1 GO:0007600| sensory perception OPRK1;TRPV2;OPRM1 GO:0006955| immune response OPRD1;CNR2;OPRK1 GO:0038003| opioid receptor signaling pathway OPRK1;OPRD1;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRK1;GPR18;PPARG GO:0042220| response to cocaine OPRM1;CNR1;SMPD1;OPRK1 GO:0031635| inhibition of adenylate cyclase activity by opioid receptor signaling pathway OPRK1;OPRM1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;OPRK1 GO:0007626| locomotory behavior OPRK1;SOD1;OPRM1 GO:0007218| neuropeptide signaling pathway GLRA3;OPRM1;OPRD1;OPRK1;GLRB;GLRA1 GO:0043278| response to morphine CNR1;OPRM1;OPRK1 20686:[DB14011 DB05098] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05098|Leptin LEPR common genes common pathways GO:0042593| glucose homeostasis CNR1;TRPV4;LEPR;PPARG GO:0008203| cholesterol metabolic process CAT;HMGCR;LEPR GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;LEPR GO:0001525| angiogenesis PTGS2;LEPR;CYP1B1 GO:0060259| regulation of feeding behavior CNR1;LEPR GO:0030217| T cell differentiation LEPR;GPR18 20687:[DB14011 DB09344] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways GO:0009750| response to fructose stimulus PTGS2;SLC2A5 GO:0070509| calcium ion import CACNA1G;CACNA1I;TRPV4;GCK;CACNA1H GO:0043312| neutrophil degranulation SLC2A5;CAT;ALOX5 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;SLC2A2;SLC2A5;ABCG2;TRPM8 GO:0015758| glucose transport SLC2A5;SLC2A2;PLA2G1B GO:0042593| glucose homeostasis GCK;CNR1;PPARG;TRPV4 GO:0008152| metabolic process GCK;ACAT1;SMPD1 GO:0032869| cellular response to insulin stimulus GCK;PLA2G1B;PPARG GO:0050796| regulation of insulin secretion CNR1;GCK;SLC2A2 20688:[DB14011 DB12202] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12202|Zalutumumab EGFR common genes common pathways GO:0008284| positive regulation of cell proliferation EGFR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;PLA2G1B;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;EGFR GO:0030324| lung development CYP1A2;EGFR GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0007623| circadian rhythm EGFR;AANAT GO:0042060| wound healing OPRM1;EGFR;ALOX15 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;EGFR GO:0007611| learning or memory CHRNA7;CNR1;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;HMGCR;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0006979| response to oxidative stress EGFR;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;TRPV1;PTGS2;OPRM1 GO:0033993| response to lipid EGFR;PPARG GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;EGFR GO:0071363| cellular response to growth factor stimulus OPRD1;CAT;EGFR;TRPV1 GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0007202| activation of phospholipase C activity EGFR;HTR2A;GPR55 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;EGFR;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0001503| ossification EGFR;ALOX15 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0035556| intracellular signal transduction EGFR;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;EGFR GO:0051592| response to calcium ion AANAT;EGFR GO:0001889| liver development EGFR;CYP1A1;ACAT1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0006970| response to osmotic stress TRPV4;EGFR GO:0001934| positive regulation of protein phosphorylation EGFR;CHRNA7 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;EGFR;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2;OPRD1 GO:0045907| positive regulation of vasoconstriction EGFR;HTR2A;PTGS2 GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;EGFR GO:0014070| response to organic cyclic compound EGFR;PPARG;CYP1A1;TRPA1;ACAT1;AANAT;PTGS2;CYP1A2 20689:[DB14011 DB01090] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways GO:0042391| regulation of membrane potential CACNA1G;GLRA1;CHRNB4;GLRB;CHRNA3;CACNA1H GO:0095500| CHRNA7;CHRNA3 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;CHRNA3;GLRB;TRPV1;CHRNA10;TRPA1;CHRNB4;GLRA1 GO:1905144| CHRNA3;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;SLC29A1;GLRA3;OPRM1;CHRNA10;GLRB;CHRNA3;TRPV1;GLRA1;CHRNB4 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;CHRNA10 GO:0001508| regulation of action potential CACNA1G;CHRNB4;GLRA1 GO:0043312| neutrophil degranulation CHRNB4;ALOX5;CAT GO:0007626| locomotory behavior OPRM1;SOD1;CHRNA3;CHRNB4 GO:0035094| response to nicotine CHRNA7;CNR1;CHRNB4 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV1;TRPV4;CHRNA10 GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA10;CACNA1I;CHRNA3;PLA2G1B;CHRNB4;GPR18;PPARG;SMPD1 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;OPRM1;CACNA1H;TRPV3;TRPM8;TRPV1;TRPV4;CACNA1I;CHRNA10;TRPA1;CACNA1G GO:0006939| smooth muscle contraction CHRNB4;HTR2A GO:0006811| ion transport TRPM8;CHRNA10;VDAC1;GLRB;CHRNA3;TRPV4;CACNA1I;TRPV1;CHRNB4;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GLRA3;TRPV3;CACNA1H GO:0051291| protein heterooligomerization GLRB;CHRNB4;GLRA1 GO:0007399| nervous system development GLRB;CHRNA3;SMPD1 GO:0060078| regulation of postsynaptic membrane potential CHRNB4;CHRNA10;CHRNA7 GO:0006816| calcium ion transport CACNA1G;TRPA1;CHRNA10;CACNA1I;TRPV4;TRPV1;TRPM8;TRPV3;CACNA1H;TRPV2;CHRNA7 20690:[DB14011 DB12140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;ALOX15;TNF GO:0006915| apoptotic process GPX1;VDAC1;IL1B GO:0000187| activation of MAPK activity SOD1;CHRNA7;TNF;IL1B;PLA2G1B GO:0045766| positive regulation of angiogenesis CHRNA7;IL1B;CYP1B1 GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;IL1B GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1;TNF GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG GO:0010628| positive regulation of gene expression TRPV4;IL6;IL1B;TNF GO:0002446| neutrophil mediated immunity PLA2G1B;IL6 GO:0032966| negative regulation of collagen biosynthetic process PPARG;IL6 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;IL1B;TNF GO:0046427| positive regulation of JAK-STAT cascade IL6;CYP1B1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B;IL6;TNF GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0071407| cellular response to organic cyclic compound CYP1B1;IL1B;CYP1A1;TNF GO:0045893| positive regulation of transcription, DNA-dependent IL1B;IL6;PPARG;TNF GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNF GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;IL6;TNF GO:0071230| cellular response to amino acid stimulus TNF;GLRA1 GO:0046330| positive regulation of JNK cascade TNF;IL1B;TRPV4 GO:0071639| positive regulation of monocyte chemotactic protein-1 production TRPV4;IL1B GO:0001660| fever generation TRPV1;IL1B GO:0042127| regulation of cell proliferation TNF;PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;IDO1;IL1B;CYP1A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;TNF GO:0009615| response to virus CYP1A1;TNF GO:0008284| positive regulation of cell proliferation IL1B;IL6;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;PPARG;IL1B;IL6;PLA2G1B GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;IL6 GO:0006919| activation of caspase activity TNF;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1;IL6 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;IL6;IL1B;OPRM1;PTGS2 GO:0051781| positive regulation of cell division CAT;IL1B GO:0050796| regulation of insulin secretion TNF;IL1B;CNR1 GO:0051384| response to glucocorticoid stimulus IL6;TNF;PTGS2 GO:0007566| embryo implantation IL1B;PTGS2;SOD1 GO:0034116| positive regulation of heterotypic cell-cell adhesion TNF;ALOX15;IL1B GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;IL1B;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;IL6;TNF GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0001934| positive regulation of protein phosphorylation CHRNA7;TNF;IL1B GO:0010629| negative regulation of gene expression TNF;OPRD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL6 GO:2000778| positive regulation of interleukin-6 secretion IL1B;TRPV4 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IL1B;IL6;PLA2G1B;TNF GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;ALOX15;IL1B;IDO1;TRPV1;IL6;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG;IL1B;IL6 GO:0006955| immune response OPRD1;CNR2;IL6;IL1B;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation PTGS2;CNR1;IL1B;TNF GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0010575| positive regulation vascular endothelial growth factor production IL1B;CYP1B1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;IL6;TRPV1;CYP1B1;IDO1;SMPD1;TNF;PPARG 20691:[DB14011 DB08520] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways GO:0031000| response to caffeine PPARG;FKBP1A GO:1902991| CHRNA7;FKBP1A GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;FKBP1A;HTR2A GO:0006936| muscle contraction FKBP1A;GLRA1;CACNA1H GO:0070588| calcium ion transmembrane transport TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1;TRPV1;TRPV4;CACNA1I;TRPM8;FKBP1A;CACNA1G;TRPA1 20692:[DB14011 DB02054] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02054|Gabaculine OAT common genes common pathways GO:0007601| visual perception OAT;GLRA1;CRYZ;GLRB;CYP1B1 20693:[DB14011 DB01646] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01646|N-Acetylmethionine RHO common genes common pathways GO:0009416| response to light stimulus AANAT;RHO GO:0007186| G-protein coupled receptor signaling pathway RHO;PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0050896| response to stimulus RHO;TRPA1;TRPM8 GO:0001523| retinoid metabolic process RHO;NAPEPLD GO:0007601| visual perception CRYZ;GLRA1;RHO;CYP1B1;GLRB GO:0007165| signal transduction GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;RHO;SMPD1;CACNA1I;PLA2G1B 20694:[DB14011 DB00183] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00183|Pentagastrin CCKBR;BCHE common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;CCKBR;HTR2A;CNR1;GPR12;PPARG;GPR18 GO:0042493| response to drug BCHE;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;CCKBR;HTR1A;HMGCR;PTGS2 GO:0007612| learning VDAC1;BCHE;PTGS2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;CCKBR;HTR2A GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BCHE;PTGS2;OPRM1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;CCKBR GO:0007165| signal transduction CCKBR;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A;CCKBR GO:0007600| sensory perception CCKBR;OPRM1;TRPV2 GO:0048565| digestive tract development CYP1A1;CCKBR GO:0007166| cell surface receptor linked signaling pathway CCKBR;TRPV1;TRPA1 20695:[DB14011 DB01088] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0006955| immune response OPRD1;CNR2;PTGDR2 GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;PTGDR2;GLRA3;HTR2A;OPRD1;OPRM1 GO:0071320| cellular response to cAMP PDE4D;AANAT GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0006811| ion transport GLRA3;CACNA1H;TRPV3;SLCO3A1;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;SLCO2B1;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1 GO:0065009| regulation of molecular function TRPV1;PTGIR GO:0007165| signal transduction HTR1A;GPR55;CNR1;GPR12;HTR2A;PTGER1;CNR2;OPRM1;PDE4D;OPRD1;PDE4A;PTGDR2;CHRNA7;PPARG;GPR18;PTGIR;SMPD1;PDE4B;PDE4C;CACNA1I;PLA2G1B GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PTGIR GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;PTGDR2 GO:0030593| neutrophil chemotaxis PDE4B;PLA2G1B;PDE4D GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;GLRA3;OPRM1;OPRD1;PTGDR2 GO:0032496| response to lipopolysaccharide CNR1;PTGER1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;PTGIR;IDO1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger PTGIR;CNR1;OPRD1;OPRM1;CNR2;PTGDR2 GO:0001666| response to hypoxia PLAT;CYP1A1;CAT;CHRNA7 GO:0055085| transmembrane transport CACNA1H;SLCO3A1;TRPV3;TRPV2;TRPA1;CACNA1G;SLCO2A1;ABCC1;ABCG2;TRPM8;SLCO2B1;TRPV1;VDAC1;CACNA1I;TRPV4 GO:0007568| aging CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PDE4D;PTGS2;CAT;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;PDE4A;OPRD1;PDE4D;OPRM1;CNR2;PTGER1;PTGDR2;PTGIR;GPR18;PPARG;PDE4C;PDE4B 20696:[DB14011 DB02884] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways GO:0006351| transcription, DNA-dependent ZFY;PPARG GO:0009791| post-embryonic development ZFY;CYP1A2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ZFY GO:0007283| spermatogenesis CNR1;SOD1;ZFY GO:0001541| ovarian follicle development ZFY;SOD1 20697:[DB14011 DB08575] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways GO:0071345| cellular response to cytokine stimulus TRPV1;MME GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR2;PTGS2;MME;OPRM1;OPRD1;HTR2A;CNR1 GO:0001822| kidney development CAT;MME GO:0043312| neutrophil degranulation ALOX5;CAT;MME 20698:[DB14011 DB08085] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;PPARG GO:0008016| regulation of heart contraction CACNA1H;THRB GO:0043401| steroid hormone mediated signaling pathway PPARG;THRB GO:0006351| transcription, DNA-dependent THRB;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;THRB GO:0006355| regulation of transcription, DNA-dependent PPARG;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;THRB;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;THRB;TRPV1 GO:0045892| negative regulation of transcription, DNA-dependent THRB;PPARG GO:0007605| sensory perception of sound GPX1;SOD1;THRB 20699:[DB14011 DB07802] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07802|3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE CSNK2A1 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CSNK2A1 GO:0006351| transcription, DNA-dependent CSNK2A1;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2;GPX1 GO:0006915| apoptotic process CSNK2A1;GPX1;VDAC1 GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG GO:0008284| positive regulation of cell proliferation CSNK2A1;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0006355| regulation of transcription, DNA-dependent PPARG;CSNK2A1 20700:[DB14011 DB08356] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways GO:0072593| reactive oxygen species metabolic process SOD1;PDK4 GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4;PDK4 GO:0042594| response to starvation ACAT1;PDK4;PPARG 20701:[DB14011 DB02350] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02350|N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide MMP3 common genes common pathways 20702:[DB14011 DB09149] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09149|Florbetapir (18F) APP common genes common pathways GO:0019731| antibacterial humoral response APP;PLA2G1B GO:0050808| synapse organization CHRNA7;APP GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0051897| positive regulation of protein kinase B signaling cascade APP;GPX1 GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:1905906| CHRNA7;APP GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:0007611| learning or memory APP;CHRNA7;CNR1 GO:0007612| learning PTGS2;VDAC1;APP GO:0008203| cholesterol metabolic process HMGCR;CAT;APP GO:0010288| response to lead ion APP;CAT GO:0045087| innate immune response APP;PPARG GO:0007155| cell adhesion CYP1B1;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;APP GO:0007626| locomotory behavior SOD1;OPRM1;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;APP GO:0002576| platelet degranulation APP;SOD1 GO:0006915| apoptotic process APP;VDAC1;GPX1 GO:0000187| activation of MAPK activity APP;PLA2G1B;SOD1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;APP;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0051262| protein tetramerization CAT;HMGCR;APP GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0010628| positive regulation of gene expression APP;TRPV4 GO:0010468| regulation of gene expression APP;CYP1A2 GO:0098815| CHRNA7;APP GO:0007186| G-protein coupled receptor signaling pathway APP;PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2;APP GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;APP;PTGS2;OPRM1 GO:0051260| protein homooligomerization GLRA1;APP;ACAT1;GLRA3 GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:1902004| CHRNA7;APP GO:0071320| cellular response to cAMP APP;AANAT GO:0010629| negative regulation of gene expression OPRD1;APP GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;GLRB;VDAC1;GLRA1;CACNA1G;APP GO:0008542| visual learning APP;HMGCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;PLA2G1B;CAT GO:0001774| microglial cell activation APP;TRPV1 GO:0007399| nervous system development GLRB;APP;SMPD1 GO:1990090| APP;TRPV1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;APP;PPARG GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;APP GO:0008344| adult locomotory behavior APP;OPRD1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;APP;CYP1B1 GO:0032930| positive regulation of superoxide anion generation SOD1;APP GO:0061844| APP;PLA2G1B GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;APP GO:0007204| elevation of cytosolic calcium ion concentration APP;TRPV4;TRPV1;OPRM1;HTR2A GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2;APP GO:0040014| regulation of multicellular organism growth SOD1;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2;OPRD1 GO:1900273| CHRNA7;APP 20703:[DB14011 DB00542] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0001666| response to hypoxia MTHFR;CHRNA7;CAT;CYP1A1 GO:0007283| spermatogenesis SOD1;CNR1;ACE GO:0055085| transmembrane transport CACNA1H;TRPV3;SLC15A2;TRPV2;CACNA1G;ABCC1;TRPA1;SLC15A1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8 GO:0043200| response to amino acid stimulus GLRB;MTHFR;GLRA3 GO:0006810| transport SLC15A2;TRPV2;SLC15A1;ABCC1;ABCG2;TRPV1;CACNA1I GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;MTHFR GO:0042493| response to drug MTHFR;PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2 GO:0001822| kidney development CAT;ACE GO:0008217| regulation of blood pressure PTGS1;ACE;PTGS2;SOD1;PPARG GO:0006811| ion transport TRPV3;CACNA1H;SLC15A2;GLRA3;TRPV2;CHRNA7;CACNA1G;SLC15A1;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8 GO:0060047| heart contraction GPX1;ACE;SOD1 GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0008152| metabolic process SMPD1;ACAT1;MTHFR 20704:[DB14011 DB00742] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00742|Mannitol ABCB1 common genes common pathways GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;VDAC1;TRPV4;ABCB1;CACNA1I;TRPV1;TRPM8;ABCG2 GO:0006810| transport TRPV2;ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1 GO:0042493| response to drug ABCB1;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 20705:[DB14011 DB00879] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00879|Emtricitabine pol;DCK;ALB common genes common pathways GO:0006139| nucleobase-containing compound metabolic process DCK;SLC29A1 GO:0001895| retina homeostasis ALB;SOD1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;ALB GO:0098869| ALB;GSR;PTGS2;GPX1;PTGS1;CAT 20706:[DB14011 DB13261] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13261|Sitafloxacin CYP1A2 common genes CYP1A2 common pathways GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;ACAT1;AANAT GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PPARG;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;HMGCR;PTGS2;CYP1A2;NAPEPLD;CYP3A4;PTGS1;NAAA;GPX1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2D6;CYP2C19 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0022900| electron transport chain GSR;IDO1;CYP1A2 GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ 20707:[DB14011 DB01790] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;PRKAR1A GO:0035556| intracellular signal transduction PLA2G1B;PRKAR1A GO:0007507| heart development PRKAR1A;PPARG GO:0045859| regulation of protein kinase activity PRKAR1A;SOD1 20708:[DB14011 DB08565] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 20709:[DB14011 DB03471] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03471|6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;DAGLA;CYP2D6;PLA2G2A;ALOX15;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0036148| PLA2G2A;PLA2G1B GO:0036149| PLA2G1B;PLA2G2A GO:0036150| PLA2G2A;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G2A GO:0050729| positive regulation of inflammatory response TRPV4;PLA2G2A GO:0050830| defense response to Gram-positive bacterium PLA2G2A;PLA2G1B GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G2A GO:0036151| PLA2G2A;PLA2G1B GO:0006644| phospholipid metabolic process PLA2G1B;PLA2G2A;NAPEPLD GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;CHRNA7;TRPV4;PLA2G2A;ALOX15 GO:0016042| lipid catabolic process NAPEPLD;PLA2G1B;DAGLA;PLA2G2A GO:0036152| PLA2G1B;PLA2G2A 20710:[DB14011 DB07749] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;CTRB1 20711:[DB14011 DB03207] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03207|2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid MMP8 common genes common pathways GO:0043312| neutrophil degranulation MMP8;CAT;ALOX5 20712:[DB14011 DB02435] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02435|Aminomethylcyclohexane murA;PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 20713:[DB14011 DB09120] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes TRPV1;CYP2C19;CYP2C9;CYP1A2 common pathways GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0098703| TRPV1 GO:0009268| response to pH TRPV1 GO:0050965| detection of temperature stimulus involved in sensory perception of pain HTR2A;TRPV1 GO:0002790| peptide secretion TRPV1 GO:0006816| calcium ion transport TRPM8;TRPV1;CACNA1I;TRPV4;TRPA1;CACNA1G;CHRNA7;TRPV2;TRPV3;CACNA1H GO:0060454| positive regulation of gastric acid secretion TRPV1 GO:0043603| cellular amide metabolic process CYP2C9 GO:0014047| glutamate secretion TRPV1 GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPV1;TRPM8;CAT GO:0009408| response to heat TRPV1;SOD1;TRPV3;TRPV2 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:1901594| TRPV1 GO:0019233| sensory perception of pain OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A;TRPA1;TRPV1 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;SOD1;CNR1;CYP2E1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0048266| behavioral response to pain TRPV1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0001774| microglial cell activation TRPV1 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:1990090| TRPV1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP2E1;CYP3A4;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0050955| thermoception TRPM8;TRPV1;TRPA1 GO:0071312| cellular response to alkaloid TRPV1 GO:0001659| temperature homeostasis HTR2A;GPX1;TRPV1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0019627| urea metabolic process CYP2C9 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7 GO:0045333| cellular respiration CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0014832| urinary bladder smooth muscle contraction TRPV1;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;HTR2A GO:0060083| smooth muscle contraction involved in micturition TRPV1 GO:0071345| cellular response to cytokine stimulus TRPV1 GO:0043434| response to peptide hormone stimulus TRPV1 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0065009| regulation of molecular function TRPV1 GO:0097267| CYP1A2;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0070588| calcium ion transmembrane transport OPRM1;CACNA1H;TRPV3;CHRNA7;TRPV2;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0050968| detection of chemical stimulus involved in sensory perception of pain TRPV1;TRPA1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CYP2E1;CAT GO:0050954| sensory perception of mechanical stimulus TRPV1 GO:0048265| response to pain TRPA1;TRPV1 GO:0050960| detection of temperature stimulus involved in thermoception TRPV1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2;TRPV1 GO:0001660| fever generation TRPV1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;GLRA1 GO:0002024| diet induced thermogenesis TRPV4;TRPV1 GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;CYP1A1;IDO1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP2E1;CYP1A2 GO:0055085| transmembrane transport TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0034220| ion transmembrane transport GLRB;TRPV1;GLRA1;TRPA1;CHRNA7;GLRA3 GO:0071615| oxidative deethylation CYP1A2 GO:0071502| cellular response to temperature stimulus TRPV1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;PPARG;CYP1A1 GO:0071356| cellular response to tumor necrosis factor TRPV1 GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1 GO:0010193| response to ozone CYP2E1;CAT GO:0007635| chemosensory behavior TRPV1 GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;TRPV2 GO:0010468| regulation of gene expression CYP1A2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;HMGCR;CYP2C9;CYP1A1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1 GO:0051209| release of sequestered calcium ion into cytosol TRPA1;TRPV1;HTR2A GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0071468| cellular response to acidity TRPV1 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 20714:[DB14011 DB06116] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06116|Eldelumab CXCL10 common genes common pathways GO:0009409| response to cold PPARG;TRPA1;CXCL10;TRPM8 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CXCL10 GO:0006955| immune response CXCL10;CNR2;OPRD1 GO:0006954| inflammatory response CXCL10;ALOX15;IDO1;TRPV1;CNR2;PTGS2;ALOX5;PTGS1 GO:0045859| regulation of protein kinase activity CXCL10;SOD1 GO:0010332| response to gamma radiation CXCL10;GPX1 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CXCL10 GO:0043950| positive regulation of cAMP-mediated signaling CXCL10;OPRM1 GO:0061844| CXCL10;PLA2G1B GO:0033280| response to vitamin D CXCL10;PTGS2 GO:0009615| response to virus CXCL10;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;CXCL10 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;CXCL10 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;CXCL10 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CXCL10;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0016525| negative regulation of angiogenesis CXCL10;PPARG GO:0007517| muscle organ development CXCL10;CACNA1H GO:0034605| cellular response to heat TRPV1;TRPV4;CXCL10;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18;CXCL10 20715:[DB14011 DB05848] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways GO:0008283| cell proliferation GPX1;HTR1A;IL12B;CYP1A1 GO:0050729| positive regulation of inflammatory response IL12B;TRPV4 GO:0048662| negative regulation of smooth muscle cell proliferation IL12B;PPARG GO:0032693| negative regulation of interleukin-10 production IDO1;IL12B GO:0019233| sensory perception of pain TRPV1;IL12B;TRPA1;OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;IL12B GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;IL12B;SOD1;PTGS2;CYP1A2 GO:0032735| positive regulation of interleukin-12 production IL12B;IDO1 GO:0002862| negative regulation of inflammatory response to antigenic stimulus IL12B;GPX1 GO:0035722| interleukin-12-mediated signaling pathway IL12B;SOD1 20716:[DB14011 DB04036] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04036|Coenzyme a Persulfide IVD common genes common pathways GO:0008152| metabolic process SMPD1;IVD;ACAT1 GO:0009083| branched chain family amino acid catabolic process ACAT1;IVD GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;IVD 20717:[DB14011 DB07240] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways GO:0001523| retinoid metabolic process TTR;NAPEPLD GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0006810| transport TTR;TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0043312| neutrophil degranulation ALOX5;TTR;CAT 20718:[DB14011 DB07944] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07944|N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE F2 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0061844| F2;PLA2G1B GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;F2;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 20719:[DB14011 DB00143] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes ABCC1;CYP3A4;GSR;GPX1 common pathways GO:0043312| neutrophil degranulation GSTP1;MGST1;MMP9;ALOX5;CAT GO:0007626| locomotory behavior HPGDS;SOD1;OPRM1 GO:0002576| platelet degranulation ABCC4;SOD1 GO:0070207| protein homotrimerization MGST1;TRPM8 GO:0035722| interleukin-12-mediated signaling pathway SOD1;GSTA2;GSTO1 GO:0043066| negative regulation of apoptotic process GSTP1;AKR1B1;MMP9;CAT;GPX1;SOD1;PTGS2;GLO1;HMGCR GO:0042311| vasodilation GPX1 GO:0032259| methylation GSTO1;CYP1A2 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0034599| cellular response to oxidative stress GPX2;CAT;GPX1;SOD1;GPX8;GPX3;GPX5;GSR;GSTP1;GPX7 GO:0014902| myotube differentiation GPX1 GO:0000302| response to reactive oxygen species SOD1;GPX1;CAT;GSTP1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;MGST2;CNR2;PTGS2;ABCC2;IDO1;MGST1;CYP1A1 GO:0009410| response to xenobiotic stimulus GPX1;GSS GO:0043523| regulation of neuron apoptosis GPX1 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0060326| cell chemotaxis ABCC1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1 GO:0010243| response to organic nitrogen MGST1;TRPV1;MGST3;ABCC4;PTGS2;MGST2 GO:0002862| negative regulation of inflammatory response to antigenic stimulus GPX1 GO:0033194| response to hydroperoxide GPX1 GO:0019372| lipoxygenase pathway ALOX5;GPX1;GPX4;PTGS2;ALOX15;LTC4S GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2;HMGCR;ABCC4 GO:0051702| interaction with symbiont GPX1 GO:1902176| GPX1 GO:0055114| oxidation-reduction process CYP1B1;GPX6;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;MGST1;CYP2D6;CYP2C9;CYP1A1;AKR1B1;CRYZ;GPX7;GLRX2;PTGS1;ALOX5;GPX1;GSTO2;ABCC4;GSTK1;GPX2;CAT;TXNDC12;CYP1A2;CYP3A7;PTGS2;GLRX;HMGCR;GPX4;GSTO1;GPX5;GPX3;CYP3A4;SOD1;GPX8 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0045444| fat cell differentiation GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;GLRX2 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;ABCC4;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2;MGST1;ABCC2 GO:0018158| protein oxidation GPX1 GO:0006691| leukotriene metabolic process GGT1;MGST2;ALOX5;ABCC1;ALOX15;LTC4S GO:0022900| electron transport chain IDO1;GSR;AKR1B1;GLRX2;GPX2;CYP1A2;GLRX GO:0099133| ABCC4;ABCC2;ABCC5;ABCC3;ABCC1 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;HPGDS;GGT1;PTGS2 GO:0043085| positive regulation of catalytic activity MGST2;SOD1;LTC4S GO:0007605| sensory perception of sound SOD1;GPX1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2D6 GO:0009266| response to temperature stimulus GLRX2;TRPV2;TRPV3;TRPM8 GO:0031100| organ regeneration PPARG;GSTP1 GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GSTP1;GPR18 GO:0098869| GPX7;GSTM2;GSTP1;GSTA1;GSTZ1;MGST1;GSR;GSTT1;GPX6;LTC4S;GPX4;PTGS2;MGST2;GPX8;GPX5;GPX3;GSTO1;GSTO2;GPX1;PTGS1;CAT;GPX2;MGST3;GSTK1 GO:0006979| response to oxidative stress GPX8;SOD1;GPX5;GPX3;GPX4;PTGS2;GPX2;CAT;GPX1;PTGS1;GPX7;ABCC2;GPX6;GSS GO:0043388| positive regulation of DNA binding PPARG;MMP9 GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCC2;ABCC5;ABCG2;ABCC3;ABCC1 GO:0007568| aging GSS;CYP1A1;CAT;GLRX2;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR GO:0009235| cobalamin metabolic process ABCC1 GO:0032355| response to estradiol stimulus GSTP1;CAT;PTGS2;CYP1A2 GO:0009611| response to wounding GPX1;CYP1A1 GO:0008202| steroid metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP1A1;CYP2C9;HMGCR;CYP3A7;CYP1A2;CYP3A4 GO:0043407| negative regulation of MAP kinase activity HMGCR;GSTP1;SMPD1 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0048741| skeletal muscle fiber development GPX1 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0006644| phospholipid metabolic process NAPEPLD;GPX4;PLA2G1B GO:2001300| LTC4S;ALOX5 GO:0010033| response to organic substance AKR1B1;PPARG;CYP1A1;TRPA1;GLRX2;ABCC4;SOD1;PTGS2;CYP1A2 GO:0007283| spermatogenesis SOD1;CNR1;GGT1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0055085| transmembrane transport ABCC5;ABCC2;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;ABCC3;CACNA1G;ABCC4;TRPV2;TRPV3;CACNA1H GO:0036378| CYP3A4 GO:0034612| response to tumor necrosis factor GSS;PTGS2 GO:0042744| hydrogen peroxide catabolic process GPX3;CAT;GPX1 GO:0030855| epithelial cell differentiation PPARG;VDAC1;GSTA1;GSTA2;GSTK1 GO:0006915| apoptotic process VDAC1;GLRX2;GPX1 GO:0046686| response to cadmium ion CAT;GSS GO:0043200| response to amino acid stimulus GLRA3;GSTP1;GSS;GLRB GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0007399| nervous system development SMPD1;GLRB;GSS GO:0001503| ossification MMP9;ALOX15 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;HPGDS;MGST3;CYP1A2;PTGS2;MGST2;HMGCR;GPX5;NAPEPLD;CYP3A4;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG GO:0034775| glutathione transmembrane transport ABCC1 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;GLRX2;CAT;SOD1 GO:0043065| positive regulation of apoptotic process MMP9;PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0001659| temperature homeostasis TRPV1;GPX1;HTR2A GO:0050727| regulation of inflammatory response PTGS2;GGT1 GO:0006805| xenobiotic metabolic process CYP3A7;MGST2;CYP1A2;GGT1;CYP3A4;PTGS1;GSTO2;MGST3;CYP2C9;GSTA4;CYP1B1;GSTP1;CYP3A5;MGST1;CYP2D6;CYP2C19 GO:0008152| metabolic process GSTM3;GSTM2;GSTM1;GSTA5;SMPD1;GSTA1;GSTZ1;GSTA4;GSTP1;GSTO1;GSTM5;GSTA2;GSTA3;ACAT1;GSTM4;GSTO2 GO:0006693| prostaglandin metabolic process PTGS2;HPGDS;PTGS1 GO:1902905| GPX1 GO:0043403| skeletal muscle tissue regeneration GPX1 GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CAT;GSTP1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;GLO1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:1904706| PPARG;GSTP1 GO:0009408| response to heat ABCC2;TRPV1;SOD1;TRPV3;TRPV2 GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPM8;TRPV1;GPX3;CAT GO:0033599| regulation of mammary gland epithelial cell proliferation GPX1 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;GPX1 GO:0008209| androgen metabolic process CYP3A4 GO:0007565| female pregnancy ABCC2;IDO1 GO:0019370| leukotriene biosynthetic process ALOX5;MGST3;MGST2;PLA2G1B;LTC4S GO:0001934| positive regulation of protein phosphorylation CHRNA7;MMP9 GO:0043534| blood vessel endothelial cell migration GPX1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0006195| purine nucleotide catabolic process GPX1 GO:0019371| cyclooxygenase pathway PTGS1;HPGDS;PTGS2 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0031667| response to nutrient levels SOD1;GSTP1;GSS GO:0007165| signal transduction HPGDS;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS;PTGS1;PLA2G1B GO:0010332| response to gamma radiation GPX1 GO:0061136| regulation of proteasomal protein catabolic process GPX1 GO:0006641| triglyceride metabolic process GPX1;CAT GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0060047| heart contraction GPX1;SOD1 GO:0060055| angiogenesis involved in wound healing GPX1 GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;GSTP1 GO:0042908| xenobiotic transport ABCC1;ABCC3;ABCG2 GO:0015889| cobalamin transport ABCC1 GO:0045454| cell redox homeostasis GSR;TXNDC12;GPX1;GLRX2;GLRX GO:0045332| phospholipid translocation ABCC1 GO:0050729| positive regulation of inflammatory response MGST2;TRPV4 GO:0007566| embryo implantation SOD1;PTGS2;MMP9 GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1 GO:0099039| ABCC1 GO:0009650| UV protection CAT;GPX1 GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:1902042| GPX1 GO:0043627| response to estrogen stimulus PPARG;GSTM3;ABCC2 GO:0001885| endothelial cell development GPX1 GO:0046466| membrane lipid catabolic process MGST2;CYP1B1 GO:0006749| glutathione metabolic process GSTA5;GSTM3;GSTM2;GSTM1;GSTA4;GSTA1;GSTZ1;GSTP1;GSTT1;GSR;GLO1;GSTA3;GGT1;GSTO1;GSTM5;GSTA2;SOD1;GSTM4;GPX1;GLRX2;GSTO2;GSTK1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;MMP9 GO:0009609| response to symbiotic bacterium GPX1 GO:0042178| xenobiotic catabolic process GSTO1;GSTM4;GSTM3;GSTM1;GSTM2;CRYZ GO:0040029| regulation of gene expression, epigenetic GPX1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0006855| drug transmembrane transport ABCC3;ABCC1;ABCG2;ABCC2 GO:0015949| nucleobase-containing small molecule interconversion GSR;GLRX GO:0001516| prostaglandin biosynthetic process PTGS1;HPGDS;PTGS2 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0051450| myoblast proliferation GPX1 GO:0010269| response to selenium ion GPX1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;ABCC4;ACAT1;AANAT;PPARG;CYP1A1;TRPA1 GO:0009636| response to toxin CYP1A1;CYP1B1;GSTP1;CAT;GPX1 20720:[DB14011 DB03466] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03466|BMS184394 RARG common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;RARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RARG GO:0032526| response to retinoic acid PPARG;RARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter RARG;PPARG;TRPV1;TRPV4 GO:0008284| positive regulation of cell proliferation RARG;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;RARG GO:0071300| cellular response to retinoic acid PPARG;RARG GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;RARG;CAT GO:0010628| positive regulation of gene expression RARG;TRPV4 GO:0010468| regulation of gene expression RARG;CYP1A2 GO:0043401| steroid hormone mediated signaling pathway PPARG;RARG GO:0006351| transcription, DNA-dependent RARG;PPARG GO:0043065| positive regulation of apoptotic process RARG;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;RARG;OPRM1;PTGS2 GO:0043010| camera-type eye development RARG;CYP1A1 20721:[DB14011 DB03176] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03176|KB-141 THRB;THRA common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter THRB;THRA;PPARG GO:0006355| regulation of transcription, DNA-dependent THRB;PPARG;THRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;PLA2G1B;PPARG;THRA GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;THRB;TRPV1;TRPV4 GO:0007611| learning or memory CHRNA7;CNR1;THRA GO:0045892| negative regulation of transcription, DNA-dependent THRB;THRA;PPARG GO:0007605| sensory perception of sound THRB;GPX1;SOD1 GO:0009409| response to cold TRPA1;PPARG;THRA;TRPM8 GO:0001503| ossification ALOX15;THRA GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;THRA;PPARG GO:0008016| regulation of heart contraction THRB;THRA;CACNA1H GO:0043401| steroid hormone mediated signaling pathway PPARG;THRA;THRB GO:0006351| transcription, DNA-dependent PPARG;THRA;THRB 20722:[DB14011 DB03697] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03697|4-Sulfonamide-[1-(4-Aminobutane)]Benzamide CA2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG;CA2 GO:0001822| kidney development CA2;CAT 20723:[DB14011 DB01785] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG;IDI1;GPX1;NAAA;PTGS1;FDPS;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR GO:0016126| sterol biosynthetic process IDI1;FDPS;HMGCR GO:0016032| viral reproduction VDAC1;FDPS;HTR2A GO:0006695| cholesterol biosynthetic process FDPS;IDI1;HMGCR GO:0008203| cholesterol metabolic process FDPS;IDI1;CAT;HMGCR GO:0006694| steroid biosynthetic process CYP17A1;FDPS;IDI1;HMGCR GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4;FDPS;IDI1 GO:0045540| regulation of cholesterol biosynthetic process FDPS;IDI1;HMGCR GO:0008299| isoprenoid biosynthetic process HMGCR;IDI1;FDPS 20724:[DB14011 DB14039] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14039|Erenumab CALCRL common genes common pathways GO:0007165| signal transduction HTR1A;GPR55;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;CHRNA7;CALCRL;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CALCRL;CACNA1G;CHRNA7;TRPV2;TRPV3;CACNA1H GO:0007507| heart development PPARG;CALCRL GO:0001525| angiogenesis PTGS2;CYP1B1;CALCRL GO:0007166| cell surface receptor linked signaling pathway TRPV1;CALCRL;TRPA1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CALCRL;OPRD1;OPRM1;CNR2;CNR1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CALCRL;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0048661| positive regulation of smooth muscle cell proliferation CALCRL;HMGCR;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;CALCRL GO:0050728| negative regulation of inflammatory response CNR2;CALCRL GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;CALCRL 20725:[DB14011 DB03683] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways GO:0071276| cellular response to cadmium ion MMP9;SOD1;CYP1A2 GO:0007566| embryo implantation MMP9;SOD1;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;MMP9 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;PPARG;MMP9;SMPD1;IDO1;CYP1B1;TRPV1 GO:0001503| ossification MMP9;ALOX15 GO:0043388| positive regulation of DNA binding MMP9;PPARG GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;MMP9 GO:0043312| neutrophil degranulation CAT;ALOX5;MMP9 20726:[DB14011 DB03393] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways GO:0016032| viral reproduction PPIA;VDAC1;HTR2A GO:0050714| positive regulation of protein secretion PPIA;PLA2G1B GO:0043312| neutrophil degranulation ALOX5;CAT;PPIA GO:0035722| interleukin-12-mediated signaling pathway PPIA;SOD1 20727:[DB14011 DB01025] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways GO:0065009| regulation of molecular function IL3;TRPV1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;GPR55;HTR1A;FGF1;OPRD1;OPRM1;CNR2;CHRNA7 GO:0050729| positive regulation of inflammatory response S100A12;TRPV4 GO:0061844| PLA2G1B;S100A12 GO:0045740| positive regulation of DNA replication IL3;PLA2G1B GO:0051781| positive regulation of cell division CAT;FGF1 GO:0008283| cell proliferation GPX1;HTR1A;FGF1;CYP1A1 GO:0007399| nervous system development GLRB;SMPD1;IL3 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;S100A12;CYP1A2;PTGS1 GO:0001525| angiogenesis PTGS2;FGF1;CYP1B1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL3;HTR2A GO:0006955| immune response CNR2;OPRD1;IL3 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;S100A12;PTGS2;IDO1;ALOX15;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;S100A12;PLA2G1B GO:0001934| positive regulation of protein phosphorylation FGF1;CHRNA7 GO:0002376| immune system process IDO1;S100A12 GO:0034605| cellular response to heat PTGS2;FGF1;TRPV1;TRPV4 GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF1;S100A12 GO:0046688| response to copper ion SOD1;AANAT;S100A13 GO:0045766| positive regulation of angiogenesis FGF1;CHRNA7;CYP1B1 GO:0000187| activation of MAPK activity FGF1;SOD1;CHRNA7;PLA2G1B GO:0043312| neutrophil degranulation ALOX5;CAT;S100A12 GO:0045087| innate immune response S100A12;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;FGF1 GO:0008284| positive regulation of cell proliferation IL3;S100A13;CHRNA7;PTGS2;HMGCR;FGF1;HTR1A;HTR2A GO:0001660| fever generation IL3;TRPV1 GO:0030324| lung development FGF1;CYP1A2 GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;GPX1 GO:0030593| neutrophil chemotaxis S100A12;PLA2G1B 20728:[DB14011 DB03744] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways GO:0042593| glucose homeostasis TRPV4;PPARG;PYGL;CNR1 GO:0043312| neutrophil degranulation CAT;ALOX5;PYGL GO:0008152| metabolic process ACAT1;SMPD1;PYGL 20729:[DB14011 DB02329] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02329|Carbenoxolone HSD11B1 common genes common pathways GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP3A4;CYP1A2;CYP3A7;HMGCR;HSD11B1 GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B1 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2;HSD11B1;CAT;PTGS1;ALOX5;GPX1 GO:0030324| lung development CYP1A2;HSD11B1 GO:0006629| lipid metabolic process CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;HSD11B1;NAAA;GPX1;PTGS1 20730:[DB14011 DB01613] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways GO:0008217| regulation of blood pressure NPR1;PTGS1;PTGS2;SOD1;NPR2;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;NPR1 GO:0001503| ossification NPR2;ALOX15 GO:0035556| intracellular signal transduction NPR1;NPR2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway NPR1;TRPV1;TRPA1 GO:0007186| G-protein coupled receptor signaling pathway NPR1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PPARG;GPR18 GO:0016525| negative regulation of angiogenesis PPARG;NPR1 GO:0030308| negative regulation of cell growth PPARG;NPR1 20731:[DB14011 DB01413] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;SLC15A1;TRPV2;SLC15A2 GO:0055085| transmembrane transport TRPA1;SLC15A1;CACNA1G;ABCC1;ABCG2;TRPM8;TRPV4;CACNA1I;VDAC1;TRPV1;SLC22A5;SLC15A2;CACNA1H;TRPV3;TRPV2 GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCG2 GO:0006811| ion transport CHRNA7;TRPV2;SLC15A2;SLC22A5;GLRA3;CACNA1H;TRPV3;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;GLRA1;TRPA1;SLC15A1;CACNA1G 20732:[DB14011 DB02016] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02016|R048-8071 LSS common genes common pathways GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9;LSS;NAAA;GPX1;PTGS1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD GO:0006695| cholesterol biosynthetic process LSS;HMGCR GO:0006694| steroid biosynthetic process LSS;CYP17A1;HMGCR GO:0045540| regulation of cholesterol biosynthetic process HMGCR;LSS 20733:[DB14011 DB02211] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02211|N-Methyl-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0009636| response to toxin CYP1A1;MAOB;CYP1B1;CAT;GPX1 GO:0010269| response to selenium ion MAOB;GPX1 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;CAT;MAOB GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;MAOB;CYP1A1 GO:0042493| response to drug ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;MAOB;CAT;SOD1;HTR2A;PTGS2;CYP1A2 GO:0022900| electron transport chain CYP1A2;MAOB;IDO1;GSR GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;MAOB;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;OPRM1;CYP1A2;CYP1A1;MAOB;IDO1 20734:[DB14011 DB01878] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01878|Benzophenone ESR1;ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0007165| signal transduction GPR18;PPARG;SMPD1;ESR2;CACNA1I;PLA2G1B;CNR1;GPR12;HTR2A;ESR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV4;TRPV1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG;ESR2 GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;ESR2;PPARG;ESR1 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 20735:[DB14011 DB05383] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05383|Pimagedine NOS2;AKR1B1;TIMP3;SLC22A2 common genes common pathways GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0006855| drug transmembrane transport SLC22A2;ABCG2;ABCC1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPM8;SLC22A2;CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0006812| cation transport SLC22A2;TRPM8 GO:0050896| response to stimulus TRPM8;TIMP3;TRPA1 GO:0007601| visual perception TIMP3;GLRB;CYP1B1;GLRA1;CRYZ GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0055085| transmembrane transport ABCC1;CACNA1G;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;SLC22A2;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TIMP3;PPARG;CYP1A1;AKR1B1;TRPA1 GO:0001666| response to hypoxia NOS2;CYP1A1;CHRNA7;CAT GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP2C9;CYP1A1;AKR1B1;CRYZ;NOS2 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0022900| electron transport chain IDO1;GSR;AKR1B1;CYP1A2 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0032496| response to lipopolysaccharide IDO1;NOS2;CYP1A1;OPRM1;CYP1A2;PTGS2;CNR2;CNR1 GO:0042127| regulation of cell proliferation NOS2;PTGS1;PTGS2 GO:0007623| circadian rhythm NOS2;AANAT GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;AKR1B1 GO:0002576| platelet degranulation SOD1;TIMP3 20736:[DB14011 DB03070] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways GO:0007623| circadian rhythm IMPDH2;AANAT GO:0043312| neutrophil degranulation IMPDH2;ALOX5;CAT GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;CYP3A4;IMPDH2;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0051289| protein homotetramerization CAT;IMPDH2;TRPV1;TRPM8;TRPA1;CRYZ 20737:[DB14011 DB09212] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0033280| response to vitamin D PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR1;HTR2A;OPRD1;PTGS2;CNR2;OPRM1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9;GPX1;NAAA;PTGS1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;TRPV1;ALOX15;IDO1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging CYP1A1;CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| GSR;PTGS1;GPX1;CAT;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;CYP1A1;PPARG GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP2C9;CYP1A1;CRYZ;GPX1;ALOX5;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2 GO:0009750| response to fructose stimulus PTGS2 GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 20738:[DB14011 DB06089] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;KCNQ3;HTR2A;KCNQ2;CACNA1G;GLRA1;GLRB;VDAC1 GO:0071320| cellular response to cAMP KCNQ1;AANAT GO:0008016| regulation of heart contraction CACNA1H;KCNQ1 GO:0086091| CACNA1G;KCNQ1 GO:0007399| nervous system development SMPD1;GLRB;KCNQ2 GO:0006811| ion transport TRPM8;KCNQ1;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPA1;GLRA1;KCNQ4;CACNA1G;CHRNA7;KCNQ5;KCNQ2;TRPV2;KCNQ3;GLRA3;TRPV3;CACNA1H GO:0034765| regulation of ion transmembrane transport KCNQ5;KCNQ2;CACNA1H;KCNQ3;KCNQ1;CACNA1I;CACNA1G;KCNQ4 GO:0055085| transmembrane transport TRPA1;KCNQ4;ABCC1;CACNA1G;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1;KCNQ1;KCNQ3;TRPV3;CACNA1H;KCNQ5;KCNQ2;TRPV2 GO:0007605| sensory perception of sound KCNQ1;KCNQ4;GPX1;SOD1 20739:[DB14011 DB00012] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00012|Darbepoetin alfa EPOR common genes common pathways GO:0007420| brain development ACAT1;EPOR GO:0007165| signal transduction HTR2A;CNR1;EPOR;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0007507| heart development PPARG;EPOR GO:0046697| decidualization PTGS2;EPOR 20740:[DB14011 DB03929] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes GLRA1 common pathways GO:1902476| GLRA3;GLRA1;GLRB GO:0008542| visual learning HMGCR;GRIN1 GO:0006816| calcium ion transport CHRNA7;TRPV2;GRIN1;CACNA1H;TRPV3;TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G GO:0001964| startle response GRIN1;GLRB;GLRA1 GO:0060013| righting reflex GLRB;GLRA1 GO:0007268| synaptic transmission GLRA1;CACNA1G;VDAC1;GLRB;GLRA3;HTR2A;OPRM1;OPRD1 GO:0043524| negative regulation of neuron apoptosis GRIN1;SOD1 GO:0071361| cellular response to ethanol GLRA1 GO:0097305| GLRA1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;GRIN1;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0045471| response to ethanol CNR1;SOD1;OPRM1;GRIN1;HMGCR;CAT GO:0019233| sensory perception of pain OPRD1;OPRM1;GRIN1;CNR2;PTGS2;HTR2A;CNR1;TRPA1;TRPV1 GO:0071294| cellular response to zinc ion GLRA1 GO:0006812| cation transport GRIN1;TRPM8 GO:0051291| protein heterooligomerization GLRA1;GLRB GO:0008344| adult locomotory behavior OPRD1;GRIN1 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPM8;TRPV3;CACNA1H;GRIN1;GLRA3;TRPV2;CHRNA7 GO:0009636| response to toxin SLC6A14;GPX1;CAT;CYP1B1;CYP1A1 GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0065009| regulation of molecular function TRPV1;GRIN1 GO:0006821| chloride transport GLRA3;GLRB;GLRA1 GO:0007613| memory HTR2A;CNR1;GRIN1;PTGS2;CHRNA7 GO:0043576| regulation of respiratory gaseous exchange GRIN1;GLRA1 GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1 GO:0046718| entry of virus into host cell SERPINB3;HTR2A GO:0060012| synaptic transmission, glycinergic GLRA3;GLRB;GLRA1 GO:0001975| response to amphetamine CNR2;GRIN1;SOD1 GO:0043278| response to morphine CNR1;GRIN1;OPRM1 GO:0050884| neuromuscular process controlling posture GLRA1 GO:0050905| neuromuscular process GRIN1;GLRB;GLRA1 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0007628| adult walking behavior GLRA1;GLRB GO:0043312| neutrophil degranulation SERPINB3;ALOX5;CAT GO:0007218| neuropeptide signaling pathway OPRM1;OPRD1;GLRA3;GLRA1;GLRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;GRIN1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;SERPINB3 GO:0007340| acrosome reaction GLRA1;GLRB GO:0071230| cellular response to amino acid stimulus GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;GLRB;TRPV1;GRIN1;OPRM1;GLRA3;SLC29A1;CHRNA7 GO:0007612| learning VDAC1;PTGS2;GRIN1 GO:0010524| positive regulation of calcium ion transport into cytosol GRIN1;PLA2G1B GO:0001508| regulation of action potential GLRA1;CACNA1G GO:0043523| regulation of neuron apoptosis GPX1;GRIN1 GO:0007611| learning or memory CHRNA7;GRIN1;CNR1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN1 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1 GO:0055085| transmembrane transport CACNA1H;SLC16A10;TRPV3;SLC6A14;TRPV2;CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0034220| ion transmembrane transport TRPA1;GLRA1;TRPV1;GLRB;GLRA3;CHRNA7 GO:0006820| anion transport GLRA1;VDAC1 GO:0051260| protein homooligomerization GLRA1;GLRA3;ACAT1 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;GRIN1;TRPM8;TRPV4 GO:0006936| muscle contraction GLRA1;CACNA1H GO:0042391| regulation of membrane potential GLRA1;CACNA1G;GLRB;GRIN1;CACNA1H GO:0006810| transport ABCC1;CACNA1I;TRPV1;ABCG2;SLC6A14;TRPV2 20741:[DB14011 DB08100] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0001523| retinoid metabolic process NAPEPLD;TTR GO:0043312| neutrophil degranulation ALOX5;CAT;TTR GO:0006810| transport TRPV2;TTR;CACNA1I;TRPV1;ABCG2;ABCC1 20742:[DB14011 DB04523] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04523|Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate CTSK common genes common pathways GO:1903146| VDAC1;CTSK GO:0045453| bone resorption GPR55;CTSK 20743:[DB14011 DB04673] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04673|4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 20744:[DB14011 DB04924] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04924|Itopride DRD2;ACHE common genes common pathways GO:0030336| negative regulation of cell migration CYP1B1;DRD2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;DRD2;CYP1B1 GO:0007270| neuron-neuron synaptic transmission VDAC1;DRD2 GO:0009636| response to toxin CAT;GPX1;DRD2;CYP1B1;CYP1A1 GO:0008283| cell proliferation CYP1A1;GPX1;ACHE;HTR1A GO:0014854| response to inactivity CAT;DRD2 GO:1900273| DRD2;CHRNA7 GO:0050482| arachidonic acid secretion PLA2G1B;DRD2 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;GPR55;HTR1A;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;DRD2;CACNA1I GO:0001975| response to amphetamine DRD2;CNR2;SOD1 GO:0001964| startle response GLRA1;DRD2;GLRB GO:0008542| visual learning HMGCR;DRD2 GO:0048149| behavioral response to ethanol OPRM1;DRD2 GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0035556| intracellular signal transduction DRD2;PLA2G1B GO:0048148| behavioral response to cocaine HTR2A;DRD2 GO:0001659| temperature homeostasis TRPV1;DRD2;HTR2A;GPX1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger DRD2;CNR1 GO:0002027| regulation of heart rate DRD2;CACNA1G GO:0007399| nervous system development SMPD1;GLRB;ACHE GO:0007194| negative regulation of adenylate cyclase activity OPRM1;DRD2 GO:0048678| response to axon injury SOD1;DRD2 GO:0045471| response to ethanol DRD2;SOD1;CNR1;OPRM1;HMGCR;CAT GO:0045776| negative regulation of blood pressure DRD2;CNR1 GO:0001666| response to hypoxia DRD2;CYP1A1;CAT;CHRNA7 GO:0014059| regulation of dopamine secretion HTR2A;DRD2 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;DRD2;GPR18 GO:0051262| protein tetramerization CAT;HMGCR;ACHE GO:0009416| response to light stimulus AANAT;DRD2 GO:0050714| positive regulation of protein secretion PLA2G1B;ACHE GO:0042220| response to cocaine DRD2;SMPD1;OPRM1;CNR1 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;ALOX15;TRPV4;DRD2 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPM8;DRD2;TRPV4 GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0051209| release of sequestered calcium ion into cytosol TRPA1;DRD2;TRPV1;HTR2A GO:0007186| G-protein coupled receptor signaling pathway DRD2;GPR18;PPARG;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0043278| response to morphine CNR1;OPRM1;DRD2 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A;DRD2 GO:0035094| response to nicotine CNR1;CHRNA7;DRD2 GO:0007517| muscle organ development CACNA1H;ACHE GO:0042493| response to drug CAT;HTR2A;SOD1;CYP1A2;PTGS2;ABCG2;DRD2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1 GO:0033602| negative regulation of dopamine secretion DRD2;CNR1 GO:0007626| locomotory behavior DRD2;SOD1;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;DRD2;PLA2G1B GO:0032228| regulation of synaptic transmission, GABAergic CNR1;DRD2 GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007628| adult walking behavior DRD2;GLRB;GLRA1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;DRD2 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;TRPV1;GLRB;DRD2;GLRA1 20745:[DB14011 DB12455] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways GO:0001895| retina homeostasis ALB;SOD1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;VDAC1;ABCB1;TRPV4;CACNA1I;TRPV3;CACNA1H;TRPV2 GO:0098869| PTGS1;GPX1;CAT;PTGS2;GSR;ALB GO:0006810| transport TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I;ABCB1 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;PPARG;CYP1A1;ABCB1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0002576| platelet degranulation ALB;SOD1 20746:[DB14011 DB00774] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:0051592| response to calcium ion KCNMA1;AANAT GO:0006970| response to osmotic stress TRPV4;KCNMA1 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;KCNMA1;CNR1;SOD1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:1902476| GLRA3;SLC12A1;GLRA1;GLRB GO:0060083| smooth muscle contraction involved in micturition TRPV1;KCNMA1 GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;KCNMA1;CACNA1H GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;ATP1A1;KCNMA1;TRPV2;SLC12A1;CHRNA7;CACNA1G;GLRA1;TRPA1;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPM8 GO:0008217| regulation of blood pressure PPARG;SOD1;ATP1A1;PTGS2;PTGS1 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0001822| kidney development CAT;CA2 GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;CA9;CAT;CYP1A2;PTGS2;ATP1A1;SOD1;HTR2A GO:0034465| response to carbon monoxide SOD1;KCNMA1 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;SLC12A1;TRPV2 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;KCNMA1;CACNA1H GO:0055085| transmembrane transport CACNA1H;TRPV3;KCNMA1;TRPV2;SLC12A1;CACNA1G;ABCC1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8 GO:0086002| ATP1A1;CACNA1G GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;SLC12A1;GLRA3;ATP1A1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1;CA2 GO:0001666| response to hypoxia CHRNA7;CAT;CA9;KCNMA1;CYP1A1 20747:[DB14011 DB04322] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04322|LY249543 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;MTHFD1;CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0008152| metabolic process MTHFD1;SMPD1;ACAT1 GO:0007507| heart development PPARG;MTHFD1 20748:[DB14011 DB04575] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04575|Quinestrol ESR1 common genes common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV4;TRPV1 GO:0007165| signal transduction CHRNA7;ESR1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;ESR1 GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;OPRM1;PTGS2;TRPV1 20749:[DB14011 DB12783] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12783|Benserazide DDC common genes common pathways GO:0071312| cellular response to alkaloid DDC;TRPV1 GO:0046219| indolalkylamine biosynthetic process DDC;AANAT GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin GPX1;DDC;CAT;CYP1B1;CYP1A1 GO:0007623| circadian rhythm AANAT;DDC GO:0071363| cellular response to growth factor stimulus TRPV1;DDC;CAT;OPRD1 20750:[DB14011 DB06350] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06350|Elinogrel P2RY12 common genes common pathways GO:0070588| calcium ion transmembrane transport TRPA1;CACNA1G;TRPM8;TRPV4;CACNA1I;TRPV1;TRPV3;CACNA1H;OPRM1;CHRNA7;P2RY12;TRPV2 GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7;P2RY12 GO:0065009| regulation of molecular function TRPV1;P2RY12 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway P2RY12;OPRM1;OPRD1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger P2RY12;CNR1 GO:0051924| regulation of calcium ion transport P2RY12;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway P2RY12;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1;P2RY12 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;P2RY12 20751:[DB14011 DB08039] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways GO:0006357| regulation of transcription from RNA polymerase II promoter CAMK2D;PPARG GO:0086091| CACNA1G;CAMK2D GO:0008016| regulation of heart contraction CAMK2D;CACNA1H GO:0071277| cellular response to calcium ion CAMK2D;ALOX15 GO:0051592| response to calcium ion CALM1;AANAT GO:0002027| regulation of heart rate CALM1;CACNA1G GO:0007399| nervous system development GLRB;SMPD1;CAMK2D GO:0002576| platelet degranulation SOD1;CALM1 GO:0035307| positive regulation of protein dephosphorylation SMPD1;CALM1 GO:0010666| positive regulation of cardiac muscle cell apoptosis CAMK2D;HMGCR GO:0007186| G-protein coupled receptor signaling pathway CALM1;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;GPR18;PPARG GO:0006936| muscle contraction CACNA1H;CALM1;GLRA1 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;TRPA1;CACNA1G;ABCC1;CALM1;TRPV2;CACNA1H;TRPV3 20752:[DB14011 DB13985] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways GO:0007584| response to nutrient CNR1;HMGCR;SSTR1;PPARG;SSTR2 GO:0008285| negative regulation of cell proliferation SSTR3;PTGS2;OPRM1;SSTR5;PPARG;SSTR1;SSTR2;SSTR4;CYP1B1 GO:0007165| signal transduction SSTR4;PLA2G1B;CACNA1I;GPR18;PPARG;SSTR1;SMPD1;SSTR2;CHRNA7;SSTR5;HTR2A;SSTR3;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0050796| regulation of insulin secretion CNR1;SSTR5 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway SSTR2;OPRD1;OPRM1 GO:0007268| synaptic transmission SSTR5;GLRA3;HTR2A;SSTR3;OPRM1;OPRD1;VDAC1;GLRB;SSTR4;GLRA1;CACNA1G GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;SSTR1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger SSTR1;SSTR2;SSTR4;SSTR3;CNR1;OPRD1;OPRM1;CNR2;SSTR5 GO:0007283| spermatogenesis SSTR2;SSTR1;SSTR3;CNR1;SOD1 GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1;SSTR5 GO:0007186| G-protein coupled receptor signaling pathway GPR18;SSTR1;PPARG;SSTR2;SSTR4;CNR1;SSTR3;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;SSTR5 GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;SSTR4;FAAH GO:0042594| response to starvation SSTR2;PPARG;SSTR1;SSTR3;ACAT1 GO:0007218| neuropeptide signaling pathway GLRB;SSTR1;GLRA1;SSTR2;GLRA3;SSTR3;OPRM1;OPRD1 20753:[DB14011 DB04615] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0042136| neurotransmitter biosynthetic process DAGLA;ACHE GO:0007399| nervous system development ACHE;GLRB;SMPD1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;ACHE GO:0007155| cell adhesion ACHE;CYP1B1 GO:0007517| muscle organ development CACNA1H;ACHE GO:0009611| response to wounding ACHE;GPX1;CYP1A1 GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0051262| protein tetramerization HMGCR;ACHE;CAT 20754:[DB14011 DB08323] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08323|3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE IGHG2 common genes common pathways GO:0002376| immune system process IGHG2;IDO1 GO:0045087| innate immune response IGHG2;PPARG 20755:[DB14011 DB03636] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03636|Glycinamid MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 20756:[DB14011 DB00480] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes PTGS2 common pathways GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;CDH5;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0045453| bone resorption GPR55;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;CNR2;PTGS1;ALOX5;IDO1;ALOX15;TRPV1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNFSF11;PLA2G1B GO:0006955| immune response OPRD1;TNFSF11;CNR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0001503| ossification ALOX15;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;GPX1;NAAA;PTGS1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0019233| sensory perception of pain TRPA1;TRPV1;OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0055085| transmembrane transport CACNA1H;TRPV3;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;TRPV4;ABCB1;CACNA1I;TRPV1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0007043| cell-cell junction assembly TRPV4;CDH5 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0051260| protein homooligomerization ACAT1;GLRA3;TNFSF11;GLRA1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0098869| GSR;PTGS1;GPX1;CAT;PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0046697| decidualization PTGS2 GO:0006810| transport TRPV2;CACNA1I;ABCB1;TRPV1;ABCG2;ABCC1 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CYP1A1 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0009750| response to fructose stimulus PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;GPX1 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;CDH5 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2;ABCB1;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0006631| fatty acid metabolic process ALOX15;PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0007155| cell adhesion CYP1B1;CDH5 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG;PLA2G1B GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;TRPV4 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 20757:[DB14011 DB04376] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04376|13-Acetylphorbol PRKCD common genes common pathways GO:0007165| signal transduction SMPD1;PRKCD;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;CHRNA7 GO:0032930| positive regulation of superoxide anion generation PRKCD;SOD1 GO:0070301| cellular response to hydrogen peroxide PRKCD;CYP1B1 GO:0042307| positive regulation of protein import into nucleus PTGS2;PRKCD GO:0035556| intracellular signal transduction PRKCD;PLA2G1B GO:0008631| induction of apoptosis by oxidative stress GPX1;PRKCD;CYP1B1 GO:0006915| apoptotic process VDAC1;PRKCD;GPX1 GO:0043407| negative regulation of MAP kinase activity HMGCR;SMPD1;PRKCD GO:0035307| positive regulation of protein dephosphorylation PRKCD;SMPD1 GO:0043312| neutrophil degranulation PRKCD;ALOX5;CAT GO:0023021| termination of signal transduction PRKCD;SMPD1 GO:0060326| cell chemotaxis PRKCD;ABCC1 GO:0050728| negative regulation of inflammatory response PRKCD;CNR2 20758:[DB14011 DB05468] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05468|R411 ITGA4 common genes common pathways GO:0007155| cell adhesion CYP1B1;ITGA4 GO:0071345| cellular response to cytokine stimulus ITGA4;TRPV1 20759:[DB14011 DB07021] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0050796| regulation of insulin secretion CNR1;DPP4 GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0043542| endothelial cell migration CYP1B1;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0001666| response to hypoxia CYP1A1;DPP4;CHRNA7;CAT 20760:[DB14011 DB07226] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07226|N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE WEE1 common genes common pathways 20761:[DB14011 DB06367] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06367|Relacatib CTSK common genes common pathways GO:0045453| bone resorption CTSK;GPR55 GO:1903146| VDAC1;CTSK 20762:[DB14011 DB07202] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways GO:0071345| cellular response to cytokine stimulus CSF1R;TRPV1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;CSF1R;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0008283| cell proliferation CSF1R;GPX1;HTR1A;CYP1A1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CSF1R;PPARG;CYP1B1 GO:0001934| positive regulation of protein phosphorylation CSF1R;CHRNA7 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;CSF1R;CNR2;PTGS2 GO:0002376| immune system process IDO1;CSF1R GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;CSF1R;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0045087| innate immune response PPARG;CSF1R GO:0008284| positive regulation of cell proliferation CSF1R;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;CSF1R;GPX1 GO:0030224| monocyte differentiation PPARG;CSF1R 20763:[DB14011 DB08791] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways GO:0008283| cell proliferation CYP1A1;MET;HTR1A;GPX1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;MET;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;MET GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PLA2G1B;PPARG 20764:[DB14011 DB06891] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06891|5-{[(4-AMINO-3-CHLORO-5-FLUOROPHENYL)SULFONYL]AMINO}-1,3,4-THIADIAZOLE-2-SULFONAMIDE CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CA2;PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 20765:[DB14011 DB08398] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08398|2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine ESR1;NCOA2 common genes common pathways GO:0048511| rhythmic process NCOA2;PPARG;AANAT GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;NCOA2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;NCOA2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;NCOA2;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0007623| circadian rhythm AANAT;NCOA2 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0007165| signal transduction ESR1;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0007204| elevation of cytosolic calcium ion concentration ESR1;HTR2A;OPRM1;TRPV1;TRPV4 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;NCOA2;PPARG;CYP1A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006351| transcription, DNA-dependent ESR1;NCOA2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 20766:[DB14011 DB00107] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0007565| female pregnancy OXTR;OXT;IDO1 GO:0060137| maternal process involved in parturition OXTR;CYP1A1 GO:0048565| digestive tract development OXTR;CYP1A1 GO:0007595| lactation SLC29A1;OXTR GO:0030431| sleep CACNA1I;OXT;OXTR;HTR2A;SLC29A1 GO:0045776| negative regulation of blood pressure CNR1;OXT GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;OXTR GO:0007507| heart development OXT;OXTR;PPARG GO:0002027| regulation of heart rate OXT;CACNA1G GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;OXT;CYP1A2;OXTR;TRPA1;PPARG;CYP1A1 GO:0042755| eating behavior OXTR;OPRD1;OPRM1;OXT GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;OXT GO:0045777| positive regulation of blood pressure OXT;CNR1;OXTR GO:0014823| response to activity CAT;OXT GO:0001975| response to amphetamine CNR2;OXT;OXTR;SOD1 GO:0043434| response to peptide hormone stimulus OXTR;OXT;TRPV1 GO:0051384| response to glucocorticoid stimulus PTGS2;OXT GO:0007613| memory CNR1;HTR2A;OXTR;OXT;PTGS2;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OXT;OPRM1;HTR2A;OXTR;TRPV1;TRPV4 GO:0032870| cellular response to hormone stimulus CACNA1H;OXTR GO:0045907| positive regulation of vasoconstriction PTGS2;OXTR;HTR2A GO:0044849| OXTR;OPRM1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;GPR55;HTR1A;OXTR;GPR12;CNR1;HTR2A;CNR2;OXT;OPRM1;OPRD1;CHRNA7 GO:0032094| response to food OPRM1;OXT;CYP1A1 GO:0042493| response to drug CAT;OXTR;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0032526| response to retinoic acid PPARG;OXT GO:0042538| hyperosmotic salinity response OXT;TRPV4 GO:0034097| response to cytokine stimulus PTGS2;OXTR;AANAT GO:0051591| response to cAMP OXT;AANAT GO:0042220| response to cocaine SMPD1;CNR1;OXTR;OPRM1;OXT GO:0051968| positive regulation of synaptic transmission, glutamatergic OXTR;PTGS2 GO:0032355| response to estradiol stimulus OXTR;OXT;CYP1A2;PTGS2;CAT GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;HTR1A;GPR55;CNR1;GPR12;HTR2A;OXTR;OPRM1;OXT;CNR2;OPRD1 GO:0006936| muscle contraction CACNA1H;OXTR;GLRA1 GO:0034695| response to prostaglandin E stimulus AANAT;OXT 20767:[DB14011 DB09214] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain CNR1;HTR2A;OPRM1;PTGS2;CNR2;OPRD1;TRPV1;TRPA1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;PPARG;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0007568| aging CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR GO:0045786| negative regulation of cell cycle PTGS2 20768:[DB14011 DB08292] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08292|(5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;HSP90AB1;SMPD1;CYP1A1;PPARG;TRPA1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;HSP90AB1 GO:0043066| negative regulation of apoptotic process HSP90AB1;GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AB1 GO:0042220| response to cocaine HSP90AB1;SMPD1;OPRM1;CNR1 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;HSP90AB1;CYP1A1;PPARG;TRPA1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HSP90AB1 GO:0043524| negative regulation of neuron apoptosis HSP90AB1;SOD1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;HSP90AB1;CYP2C19;CYP2D6;CYP3A5;CYP1B1 GO:0001890| placenta development PPARG;HSP90AB1;SOD1 20769:[DB14011 DB00659] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0060080| regulation of inhibitory postsynaptic membrane potential GABRB3;GLRA1 GO:2000463| positive regulation of excitatory postsynaptic membrane potential GRIN1;CHRNA7 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC36A1;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1 GO:0034220| ion transmembrane transport GABRB3;CHRNA7;GABRG3;GABRA6;GABRA4;GLRA3;GABRA1;GABRE;GABRG2;GABRB1;GABRQ;GABRA2;TRPV1;GRIN3B;GLRB;GRIN3A;GABRD;GABRB2;GABRP;GLRA1;TRPA1;GABRG1;GABRA5;GABRA3 GO:0007216| metabotropic glutamate receptor signaling pathway DAGLA;GRM5 GO:0007605| sensory perception of sound GABRB3;GPX1;SOD1;GABRB2;GABRA5 GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;GRIN1;TRPM8;TRPV4 GO:0042391| regulation of membrane potential GRIN2A;CACNA1H;GRIN1;GLRB;GLRA1;GRIN2C;CACNA1G GO:0006810| transport GABRA4;GABRA6;GRIN2B;GABRA1;GABRG2;GABRB1;GABRB3;GRIN2A;TRPV2;GABRB2;GABRD;GRIN2C;GABRA5;ABCC1;GABRA3;ABCG2;TRPV1;CACNA1I GO:0009611| response to wounding GPX1;GRIN2A;GRIN2C;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;GRM5;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;PPARG;GPR18 GO:0043278| response to morphine CNR1;OPRM1;GRIN1 GO:0050808| synapse organization GRM5;CHRNA7 GO:0050905| neuromuscular process GLRB;GLRA1;GRIN1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;GRIN2A;GABRG3;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PPARG;PLA2G1B GO:0007626| locomotory behavior GRM5;OPRM1;SOD1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;GRIN2A;SLC29A1;GRIN2B;GLRA3;OPRM1;GRIN1;GRIN2D;TRPV1;GLRB;GRIN3B;GRIN3A;GLRA1;GRIN2C GO:0043523| regulation of neuron apoptosis GRIN1;GPX1;GABRB3;GABRA5;GABRB2 GO:0007611| learning or memory GRIN2A;CHRNA7;GRM5;GRIN1;CNR1;GRIN2B GO:0007612| learning GRIN2A;GRM5;PTGS2;GRIN1;VDAC1 GO:0010524| positive regulation of calcium ion transport into cytosol GRIN1;PLA2G1B GO:0006812| cation transport GRIN1;TRPM8 GO:0001662| behavioral fear response HTR1A;VDAC1;GABRA5 GO:0051966| regulation of synaptic transmission, glutamatergic CNR1;GRM5 GO:0009791| post-embryonic development GABRG2;CYP1A2 GO:0008344| adult locomotory behavior GRIN2D;GRIN1;OPRD1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;GABRB1 GO:0051930| regulation of sensory perception of pain OPRD1;GRIN2D;OPRM1;GRIN2A GO:0006811| ion transport GLRA3;GABRA1;GRIN2B;GABRA6;GABRA4;GABRQ;GABRG2;TRPV3;GABRB1;GRIN2D;GRIN1;CACNA1H;GABRE;GRIN2A;CHRNA7;GABRG3;GABRB3;SLC36A1;TRPV2;GLRA1;TRPA1;GABRP;GABRD;GABRB2;GRIN3A;GABRA3;GABRA5;CACNA1G;GRIN2C;GABRG1;TRPM8;GABRA2;GRIN3B;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1 GO:0065009| regulation of molecular function GRIN2A;GRIN2B;GRIN1;GRIN2D;TRPV1;GRIN2C GO:0007165| signal transduction GABRB1;GRM5;OPRD1;GABRQ;OPRM1;GABRE;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;GABRA6;CHRNA7;GABRB3;SMPD1;GABRA5;GPR18;GABRP;PPARG;GABRD;PLA2G1B;CACNA1I GO:0007420| brain development ACAT1;GABRA5 GO:1900273| CHRNA7;GRIN2A GO:0006821| chloride transport GLRB;GABRA2;GABRG1;GABRA5;GABRA3;GABRB2;GABRD;GABRP;GLRA1;GABRB3;GABRG3;GABRE;GABRG2;GABRB1;GABRQ;GABRA6;GABRA4;GLRA3;GABRA1 GO:0070588| calcium ion transmembrane transport CACNA1I;GRIN3B;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1;GRIN3A;TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1 GO:0022008| neurogenesis DAGLA;GRIN2A GO:0007613| memory GRIN2A;CHRNA7;HTR2A;CNR1;GRIN1;PTGS2 GO:0043576| regulation of respiratory gaseous exchange GRIN1;GLRA1 GO:0001975| response to amphetamine SOD1;GRIN1;CNR2;GRIN2A GO:0050890| cognition CHRNA7;GRM5 GO:0008542| visual learning GRIN2A;GRIN1;HMGCR GO:0051924| regulation of calcium ion transport GRIN3B;OPRD1 GO:1902476| GABRQ;GABRG2;GABRB1;GABRE;GLRA3;GABRA1;GABRA6;GABRA4;GABRG3;GABRB3;GABRA3;GABRA5;GABRG1;GLRA1;GABRP;GABRB2;GABRD;GLRB;GABRA2 GO:0006816| calcium ion transport TRPV3;CACNA1H;GRIN1;TRPV2;CHRNA7;GRIN2A;CACNA1G;TRPA1;GRIN3A;TRPV1;TRPV4;CACNA1I;TRPM8 GO:0001964| startle response GLRB;GLRA1;GRIN2A;GRIN1;GRIN2D GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;GABRB2;GABRD;GABRA5;GABRG1;CACNA1G;GRIN2A;HTR2A;GLRA3;GRIN2B;GABRG2;GRM5;OPRD1;OPRM1 GO:0043524| negative regulation of neuron apoptosis SOD1;GRIN1;GABRB3;GABRB2;GABRA5 GO:0060078| regulation of postsynaptic membrane potential GRM5;GABRA1;GRIN2A;CHRNA7 GO:0042428| serotonin metabolic process GRIN2A;HTR1A GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;GRIN1;GRIN2A;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0030431| sleep CACNA1I;HTR2A;SLC29A1;GRIN2A GO:0019233| sensory perception of pain TRPV1;TRPA1;GRIN2A;HTR2A;CNR1;OPRD1;GRIN1;CNR2;PTGS2;OPRM1 GO:0045471| response to ethanol GRIN3A;GRIN2A;CAT;CNR1;SOD1;GRIN2B;HMGCR;OPRM1;GRIN1 20770:[DB14011 DB05540] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways GO:0002376| immune system process ADSS;IDO1;ADSSL1 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SLC7A11;SOD1 GO:0035094| response to nicotine CNR1;SLC7A11;CHRNA7 GO:0042594| response to starvation ADSSL1;PPARG;ACAT1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC7A11 GO:0007420| brain development SLC7A11;ACAT1 20771:[DB14011 DB07353] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07353|4-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOL F2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0061844| PLA2G1B;F2 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;PPARG;GPR18;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 20772:[DB14011 DB03331] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03331|N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0045821| positive regulation of glycolysis GAPDHS;HTR2A GO:0030317| sperm motility GAPDHS;CACNA1I GO:0055114| oxidation-reduction process GAPDHS;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT 20773:[DB14011 DB09043] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09043|Albiglutide GLP1R common genes common pathways GO:0045777| positive regulation of blood pressure CNR1;GLP1R GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GLP1R;GPR18;PPARG GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;GLP1R;HTR2A;OPRM1 GO:0050796| regulation of insulin secretion CNR1;GLP1R GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;GLP1R GO:0008016| regulation of heart contraction CACNA1H;GLP1R GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GLP1R;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0007611| learning or memory GLP1R;CNR1;CHRNA7 20774:[DB14011 DB00239] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes CYP3A4;CYP2C19 common pathways GO:0042908| xenobiotic transport ABCC1;NR1I2;ABCG2 GO:0070989| oxidative demethylation CYP2D6;CYP3A5;CYP2C9;CYP3A4;CYP1A2 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;NR1I2;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0097267| CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0006351| transcription, DNA-dependent NR1I2;PPARG GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG GO:0006805| xenobiotic metabolic process NR1I2;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;NR1I2;CYP2C9;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0008202| steroid metabolic process NR1I2;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0036378| CYP3A4 GO:0010628| positive regulation of gene expression TRPV4;NR1I2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0045892| negative regulation of transcription, DNA-dependent NR1I2;PPARG GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;PPARG;PLA2G1B GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0006355| regulation of transcription, DNA-dependent NR1I2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP1A1;CYP2C9;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;PPARG 20775:[DB14011 DB00666] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GNRHR2;GNRHR;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55 GO:0007165| signal transduction HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;GNRHR;PLA2G1B;CACNA1I;GNRHR2 20776:[DB14011 DB07697] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07697|1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine PKM common genes common pathways GO:0001666| response to hypoxia CYP1A1;PKM;CHRNA7;CAT GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PKM;PTGS2;CYP1A2;SOD1 GO:0031100| organ regeneration PKM;PPARG GO:0043312| neutrophil degranulation CAT;PKM;ALOX5 GO:0032868| response to insulin stimulus CAT;AANAT;PKM;TRPV4 GO:0007584| response to nutrient HMGCR;CNR1;PKM;PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PKM GO:0051289| protein homotetramerization CAT;PKM;TRPM8;TRPV1;TRPA1;CRYZ GO:0043403| skeletal muscle tissue regeneration GPX1;PKM GO:0001889| liver development PKM;ACAT1;CYP1A1 GO:0008152| metabolic process SMPD1;PKM;ACAT1 20777:[DB14011 DB03959] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03959|N,O6-Disulfo-Glucosamine FGF2;FGF1;HS3ST3A1;HGF;ANXA5 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent FGF2;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade HGF;FGF1;FGF2;GPX1 GO:0060326| cell chemotaxis ABCC1;HGF GO:0050728| negative regulation of inflammatory response HGF;CNR2 GO:0030324| lung development CYP1A2;FGF1 GO:0042060| wound healing ALOX15;OPRM1;FGF2 GO:0002576| platelet degranulation HGF;SOD1;ANXA5 GO:0008284| positive regulation of cell proliferation CHRNA7;FGF2;PTGS2;HMGCR;FGF1;HTR1A;HTR2A;HGF GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;FGF2;PPARG;HGF;PLA2G1B GO:0043066| negative regulation of apoptotic process HGF;CAT;GPX1;SOD1;ANXA5;HMGCR;PTGS2 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;FGF2;OPRM1;HTR2A;GPR55;CHRNA7;TRPV4;ALOX15 GO:0000187| activation of MAPK activity FGF1;SOD1;FGF2;CHRNA7;HGF;PLA2G1B GO:0045766| positive regulation of angiogenesis FGF2;FGF1;CHRNA7;CYP1B1;HGF GO:0043406| positive regulation of MAP kinase activity FGF1;HTR2A;FGF2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;ANXA5;CYP1A2;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade HGF;CAT GO:0051209| release of sequestered calcium ion into cytosol FGF2;HTR2A;TRPV1;TRPA1 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2;FGF1 GO:0031100| organ regeneration PPARG;HGF GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process HGF;GPX1;PTGS2 GO:0001934| positive regulation of protein phosphorylation FGF1;CHRNA7 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HGF;HTR2A GO:0001525| angiogenesis FGF2;PTGS2;FGF1;CYP1B1 GO:0001889| liver development ACAT1;CYP1A1;HGF GO:0061045| negative regulation of wound healing HMGCR;FGF2 GO:0007399| nervous system development FGF2;SMPD1;GLRB GO:0051450| myoblast proliferation GPX1;HGF GO:0008283| cell proliferation CYP1A1;HGF;HTR1A;FGF1;GPX1 GO:1902042| GPX1;HGF GO:0043537| negative regulation of blood vessel endothelial cell migration FGF2;PPARG GO:0051781| positive regulation of cell division CAT;FGF1;FGF2 GO:0090201| negative regulation of release of cytochrome c from mitochondria HGF;GPX1 GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;GPR12;CNR1;FGF1;GPR55;HTR1A;ANXA5;OPRD1;CNR2;FGF2;OPRM1 20778:[DB14011 DB06982] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06982|(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid SKP1 common genes common pathways GO:0006879| cellular iron ion homeostasis SKP1;SOD1;ABCG2 20779:[DB14011 DB04224] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes PPARG common pathways GO:0030308| negative regulation of cell growth PPARD;PPARG GO:0008203| cholesterol metabolic process RXRA;CAT;HMGCR;PPARD GO:0042127| regulation of cell proliferation PTGS1;PPARD;PTGS2 GO:0042060| wound healing PPARA;OPRM1;PPARD;ALOX15 GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0032526| response to retinoic acid PPARG;RXRA GO:0006635| fatty acid beta-oxidation ACAT1;PPARD GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0043066| negative regulation of apoptotic process SOD1;PPARD;HMGCR;PTGS2;FABP1;CAT;GPX1;ALB GO:0071300| cellular response to retinoic acid PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;RXRA;PPARG;PLA2G1B GO:0002576| platelet degranulation SOD1;ALB GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042594| response to starvation PPARG;ACAT1 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARD;PPARA;PPARG;RXRA;TRPV1;TRPV4 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;PPARA;PPARD GO:0006631| fatty acid metabolic process ALOX15;FABP3;PTGS1;PPARA;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARD;PPARA;RXRA;PPARG GO:0042493| response to drug SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;FABP3;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0030224| monocyte differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARA;PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0050728| negative regulation of inflammatory response PPARD;CNR2;PPARA GO:0071455| cellular response to hyperoxia PPARG GO:0033189| response to vitamin A CAT;PPARD;CYP1A1;PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA;PPARA;PPARD GO:0006687| glycosphingolipid metabolic process SMPD1;GLTP GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PPARG;GPR18 GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PPARD;CAT GO:0046697| decidualization PTGS2;PPARD GO:0015909| long-chain fatty acid transport FABP1;FABP3;PPARG GO:0071456| cellular response to hypoxia PTGS2;FABP1;PPARD;OPRD1;SLC29A1 GO:0010468| regulation of gene expression CYP1A2;PPARA GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0098869| ALB;GSR;PTGS2;FABP1;GPX1;PTGS1;CAT GO:0010891| negative regulation of sequestering of triglyceride PPARA;PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0032966| negative regulation of collagen biosynthetic process PPARG;PPARD GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0006915| apoptotic process GPX1;PPARD;VDAC1 GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARA;PPARG GO:0001666| response to hypoxia CHRNA7;CAT;PPARA;CYP1A1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1;GC GO:0010628| positive regulation of gene expression PPARD;TRPV4 GO:0015758| glucose transport PLA2G1B;PPARD GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARD;FABP4;PPARG GO:0010033| response to organic substance PPARD;PTGS2;CYP1A2;SOD1;TRPA1;PPARG;CYP1A1 GO:0048511| rhythmic process PPARA;AANAT;PPARG GO:0071356| cellular response to tumor necrosis factor FABP4;TRPV1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter RXRA;PPARG;PPARD GO:0006351| transcription, DNA-dependent PPARA;PPARD;PPARG;RXRA GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRA;PPARD;PPARA GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0048469| cell maturation PPARG GO:0045776| negative regulation of blood pressure CNR1;PPARA GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0042953| lipoprotein transport PPARG GO:0006629| lipid metabolic process PPARA;NAPEPLD;CYP3A4;HMGCR;PPARD;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0051974| negative regulation of telomerase activity PPARG GO:0045165| cell fate commitment PPARG GO:0007399| nervous system development GLRB;SMPD1;FABP7 GO:0007507| heart development PPARA;PPARD;PPARG;RXRA GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;FABP1;GPX1 GO:0061614| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0001964| startle response FABP7;GLRB;GLRA1 GO:0016032| viral reproduction VDAC1;RXRA;HTR2A GO:0051289| protein homotetramerization TRPV1;TRPM8;CRYZ;TRPA1;RXRA;CAT GO:1904706| PPARG GO:0050872| white fat cell differentiation FABP4;PPARG GO:0042752| regulation of circadian rhythm PPARA;PPARG GO:0007566| embryo implantation RXRA;SOD1;PTGS2;PPARD GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;RXRA;FABP1;HMGCR;PPARA;CNR1 GO:0050729| positive regulation of inflammatory response FABP4;TRPV4 GO:1905461| PPARG GO:0022008| neurogenesis FABP7;DAGLA GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0043010| camera-type eye development CYP1A1;RXRA GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;PPARD GO:0070542| response to fatty acid CAT;PTGS2;FABP3 GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG;PPARA GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0006919| activation of caspase activity PPARG GO:0008283| cell proliferation GPX1;HTR1A;PPARD;CYP1A1 GO:0001895| retina homeostasis ALB;SOD1 GO:0032868| response to insulin stimulus TRPV4;FABP3;CAT;AANAT;PPARA GO:0055088| lipid homeostasis PPARG GO:0019395| fatty acid oxidation PPARG;PPARD GO:0060612| adipose tissue development PPARD;ACAT1 GO:0001890| placenta development PPARD;SOD1;RXRA;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARA;PPARG GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A;PPARD GO:0014823| response to activity CAT;PPARD GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0008285| negative regulation of cell proliferation PPARG;FABP3;CYP1B1;PTGS2;OPRM1;FABP7 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0007584| response to nutrient HMGCR;CNR1;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1;FABP1 GO:0043627| response to estrogen stimulus PPARG 20780:[DB14011 DB06719] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR2;OPRM1;OPRD1;LHCGR;CNR1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GNRHR;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;LHCGR;GPR55;HTR1A GO:0006694| steroid biosynthetic process HMGCR;CYP17A1;CYP19A1 GO:0022900| electron transport chain CYP19A1;GSR;IDO1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT;CYP2C9;CYP1A1;CYP19A1;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger LHCGR;HTR2A;OPRM1;OPRD1 GO:0007165| signal transduction LHCGR;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;GNRHR;CACNA1I;PLA2G1B GO:0050890| cognition CHRNA7;LHCGR GO:0008209| androgen metabolic process CYP19A1;CYP3A4 GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1 20781:[DB14011 DB14487] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes SOD1;GLRA1 common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;FGA GO:0006821| chloride transport GLRA3;GLRA1;GLRB GO:1900273| INS;CHRNA7;APP GO:0048662| negative regulation of smooth muscle cell proliferation TP53;PPARG GO:0010811| positive regulation of cell-substrate adhesion VTN;ALOX15 GO:0001819| positive regulation of cytokine production SOD1;AGT GO:0060047| heart contraction SOD1;GPX1 GO:0070542| response to fatty acid PON1;PTGS2;CAT GO:0065009| regulation of molecular function TRPV1;AGT;IL3 GO:0010332| response to gamma radiation TP53;TP73;PARP1;GPX1 GO:0034644| cellular response to UV PTGS2;TP73;TP53 GO:0006641| triglyceride metabolic process APOBR;APOE;APOA2;GPX1;CAT GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;FGA GO:2000344| positive regulation of acrosome reaction CACNA1H;GLRA1 GO:0090336| positive regulation of brown fat cell differentiation INS;PTGS2 GO:0007420| brain development MT3;ACAT1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;APP GO:0007165| signal transduction CHRNA7;JUP;HTR2A;C3;CNR1;GPR12;HTR1A;GPR55;ESR1;OPRD1;OPRM1;CNR2;IGFALS;FGA;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;PDIA3;BDKRB1 GO:0045454| cell redox homeostasis GSR;PRDX1;PDIA3;GPX1;P4HB GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0060012| synaptic transmission, glycinergic GLRA3;GLRA1;GLRB GO:0001975| response to amphetamine HDAC1;SOD1;CNR2 GO:0007566| embryo implantation PTGS2;SOD1;MMP9 GO:0040014| regulation of multicellular organism growth APP;SOD1 GO:0090201| negative regulation of release of cytochrome c from mitochondria CLU;GPX1 GO:0019216| regulation of lipid metabolic process APOA1;SERPINA3;PPARG;CYP1A1;APOA2;AGT;CNR1;HMGCR GO:0050729| positive regulation of inflammatory response TRPV4;S100A9;S100A8;AGT GO:0046718| entry of virus into host cell HTR2A;SIVA1;IDE GO:0072593| reactive oxygen species metabolic process SOD1 GO:0050890| cognition CHRNA7;INS GO:0051384| response to glucocorticoid stimulus CPN1;APOA2;PTGS2 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRM1;OPRD1 GO:0002262| myeloid cell homeostasis SOD1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;KNG1;BDKRB1;APP;AGT;ESR1;HTR2A;OPRM1 GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0032869| cellular response to insulin stimulus PARP1;PPARG;PLA2G1B GO:0007613| memory CHRNA7;PTGS2;CNR1;HTR2A;APP GO:0048146| positive regulation of fibroblast proliferation FN1;PLA2G1B;ESR1;AGT GO:0045740| positive regulation of DNA replication IL3;INS;PLA2G1B GO:0001523| retinoid metabolic process NAPEPLD;TTR;APOA2;APOA4;APOE;APOA1 GO:0010043| response to zinc ion S100A8;AANAT;KRT14 GO:0055088| lipid homeostasis PPARG;APOA4;APOE GO:0051291| protein heterooligomerization GLRB;SEMG1;HBB;GLRA1;IDE;HBA1;JUP GO:0001890| placenta development PPARG;SOD1 GO:0006749| glutathione metabolic process SOD1;GPX1;GSR GO:0034976| response to endoplasmic reticulum stress ALOX15;PDIA3;P4HB GO:0030336| negative regulation of cell migration KRT16;CYP1B1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;GSN;MT3;MMP9;MT1A GO:0035865| cellular response to potassium ion SOD1;CACNA1H GO:0008217| regulation of blood pressure HBB;PPARG;AGT;PTGS1;PTGS2;SOD1 GO:0008285| negative regulation of cell proliferation TP73;CYP1B1;HDAC1;PPARG;HDAC4;TP53;APP;NME1;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;APOE GO:0032930| positive regulation of superoxide anion generation APP;AGT;SOD1 GO:0061844| DCD;S100A9;KRT6A;PLA2G1B;KNG1;F2;SEMG1;S100A7;APP GO:1902042| FGA;GPX1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;APOA1 GO:0070301| cellular response to hydrogen peroxide MDM2;CYP1B1 GO:0043627| response to estrogen stimulus ESR1;APOA1;PPARG;APOA2 GO:0014070| response to organic cyclic compound TP53;TRPA1;CYP1A1;PPARG;AANAT;ACAT1;PTGS2;CYP1A2;MGMT GO:0002227| innate immune response in mucosa APOA4;PLA2G1B GO:0009636| response to toxin CYP1A1;MDM2;CYP1B1;PON1;MGMT;CAT;GPX1 GO:0009395| phospholipid catabolic process NAPEPLD;APOA2 GO:0009411| response to UV TP53;CAT GO:0046620| regulation of organ growth SOD1 GO:0006919| activation of caspase activity PPARG;PDCD6;S100A8;S100A9 GO:0032088| negative regulation of NF-kappaB transcription factor activity SIVA1;CAT;CYP1B1 GO:0008283| cell proliferation GPX1;MT3;HTR1A;PRDX1;TP53;KRT16;CYP1A1 GO:0046340| diacylglycerol catabolic process DAGLA;APOA2 GO:2000378| negative regulation of reactive oxygen species metabolic process VDAC1;MT3 GO:0006811| ion transport CHRNA7;CP;TRPV2;GLRA3;TF;TRPV3;CACNA1H;TRPM8;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;TRPA1;GLRA1;CACNA1G GO:0042633| hair cycle PTGS2;KRT16;KRT14 GO:0045777| positive regulation of blood pressure CNR1;AGT GO:0008344| adult locomotory behavior APP;OPRD1 GO:0001895| retina homeostasis KRT1;SOD1;IGHA1;TF;JCHAIN;PRDX1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1 GO:0040029| regulation of gene expression, epigenetic GPX1;HDAC4 GO:0046470| phosphatidylcholine metabolic process PON1;PLA2G1B;APOA4 GO:0044240| multicellular organismal lipid catabolic process APOA4;PLA2G1B GO:0015949| nucleobase-containing small molecule interconversion GSR;NME1 GO:0008152| metabolic process SMPD1;ASPA;IDE;ACAT1;CPE;TPI1 GO:0042310| vasoconstriction AGT;HTR1A GO:0042307| positive regulation of protein import into nucleus JUP;PTGS2 GO:0042542| response to hydrogen peroxide TRPA1;HBB;HBA1;CAT;GPX1;SOD1 GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0050727| regulation of inflammatory response PGLYRP2;ESR1;S100A8;PTGS2;S100A9;AHSG GO:0071312| cellular response to alkaloid MDM2;TRPV1 GO:0043065| positive regulation of apoptotic process IDO1;KNG1;TP73;CYP1B1;TRPV1;MMP9;PPARG;SMPD1;TP53;APP;CLU;SOD1;CNR1;PTGS2 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0097305| GLRA1 GO:0042572| retinol metabolic process TTR;CYP1B1 GO:0071260| cellular response to mechanical stimulus PTGS2;AGT;HDAC4 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;APOA1;APOBR;CYP2D6;ALOX15;CLU;APOE;CYP2C9;PPARG;GPX1;NAAA;PTGS1;HMGCR;CYP1A2;APOL1;PTGS2;C3;PON1;NAPEPLD;CYP3A4 GO:0051974| negative regulation of telomerase activity PPARG;TP53 GO:0071361| cellular response to ethanol GLRA1 GO:0002027| regulation of heart rate CACNA1G;MDM2;AGT GO:0007399| nervous system development IL3;NME1;SMPD1;APP;HDAC4;APLP1;GLRB GO:0001503| ossification MMP9;AHSG;ALOX15 GO:0007507| heart development PPARG;MDM2 GO:1990090| TRPV1;APP GO:0071294| cellular response to zinc ion PARP1;GLRA1;MT2A;MT1A GO:0000303| response to superoxide SOD1 GO:0086091| DSP;CACNA1G;JUP GO:0008090| retrograde axon cargo transport SOD1 GO:0061045| negative regulation of wound healing APCS;HMGCR GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;C3;C5;CYP1B1 GO:0001774| microglial cell activation TRPV1;APP;CLU GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;APOE;ESR1 GO:0019233| sensory perception of pain BDKRB1;TRPA1;TRPV1;OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A GO:0045541| negative regulation of cholesterol biosynthetic process SOD1;APOE GO:0045773| positive regulation of axon extension FN1;TRPV2 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0006351| transcription, DNA-dependent HDAC8;PARP1;ESR1;TP73;ENO1;TP53;EEF1A1;HDAC1;PPARG;HDAC4 GO:0051592| response to calcium ion FGA;PDCD6;AANAT GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0001525| angiogenesis S100A7;FN1;PDCD6;CYP1B1;PTGS2 GO:0007166| cell surface receptor linked signaling pathway AGT;C5;F2;TRPV1;TRPA1 GO:0045821| positive regulation of glycolysis INS;HTR2A;GAPDHS GO:0045471| response to ethanol CAT;SOD1;CNR1;MGMT;HMGCR;GSN;OPRM1;S100A8;TUFM;TP53 GO:0045776| negative regulation of blood pressure BDKRB1;CNR1 GO:0000060| protein import into nucleus, translocation OPRD1;MT3 GO:0043087| regulation of GTPase activity SOD1 GO:0060013| righting reflex GLRB;GLRA1 GO:0019226| transmission of nerve impulse SOD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;PPARG;APP;ESR1;JUP GO:0016032| viral reproduction SIVA1;HTR2A;VDAC1;TP73;CFH;APOA2;MDM2;TP53;IDE;HDAC1 GO:0001964| startle response GLRA1;GLRB GO:0006955| immune response C8B;C1R;IGKV1-17;JCHAIN;IGHA1;C1QC;C3;IGLV3-21;CNR2;VTN;C8A;OPRD1;IL3 GO:0010942| positive regulation of cell death HBA1;HBB;MT3;PTGS2 GO:0006954| inflammatory response C4B;ALOX5;PTGS1;S100A9;PTGS2;CNR2;S100A8;C3;KLKB1;C5;KNG1;SERPINA3;TRPV1;IDO1;ALOX15;BDKRB1;KRT16;HDAC4 GO:1902430| CLU;APOE;CHRNA7 GO:0051092| positive regulation of NF-kappaB transcription factor activity AGT;INS;CAT;S100A9;S100A8;PLA2G1B;APP;CLU GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1 GO:0051289| protein homotetramerization CAT;TP53;ALDOA;CRYZ;TRPA1;IDE;TRPV1;TRPM8 GO:0010976| positive regulation of neuron projection development CNR1;AGT;NME1;APOE GO:0008542| visual learning HMGCR;APP GO:0006879| cellular iron ion homeostasis CP;SOD1;TF;ABCG2 GO:0007595| lactation NME1;SLC29A1 GO:0019430| removal of superoxide radicals APOA4;PRDX1;SOD1;MT3 GO:1902476| GLRB;GLRA1;APOL1;GLRA3 GO:0051924| regulation of calcium ion transport AGT;OPRD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;TP53;VTN;HTR2A;AGT;IL3;INS GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels PON1;SOD1;PSPH GO:0071603| endothelial cell-cell adhesion CYP1B1;JUP GO:0071320| cellular response to cAMP APP;AANAT GO:0043524| negative regulation of neuron apoptosis SOD1;MT3;APOE;HDAC1;TP73 GO:0010629| negative regulation of gene expression APP;MDM2;HDAC1;AGT;NME1;HDAC8;OPRD1;ESR1 GO:0007268| synaptic transmission GLRB;VDAC1;CACNA1G;APP;GLRA1;OPRM1;OPRD1;HTR2A;GLRA3 GO:0001934| positive regulation of protein phosphorylation C3;CHRNA7;MT3;MMP9;APP;F2 GO:0043534| blood vessel endothelial cell migration GPX1;APOA1 GO:1902004| APP;APOE;CLU;CHRNA7 GO:0007565| female pregnancy IDO1;PZP;AGT GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MT3;GPX1;PTGS2;MDM2 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042391| regulation of membrane potential CACNA1H;CACNA1G;GLRA1;GLRB GO:0006979| response to oxidative stress PRDX1;APOE;TP53;APP;PTGS1;GPX1;CAT;KRT1;MT3;PTGS2;SOD1 GO:1901214| APOE;CLU;CHRNA7 GO:0043388| positive regulation of DNA binding NME1;PPARG;MMP9 GO:0045429| positive regulation of nitric oxide biosynthetic process AGT;INS;PTGS2;OPRM1;ESR1;TRPV1;APP;CLU;HBB GO:0006936| muscle contraction CACNA1H;GLRA1;UTRN GO:0098869| PTGS2;S100A9;PTGS1;GPX1;CAT;APOE;HBB;HBA1;GSR GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPM8;TRPV4;APOE GO:0048538| thymus development SOD1 GO:0051260| protein homooligomerization GLRA3;ACAT1;APP;IDE;GLRA1 GO:0002376| immune system process C4BPB;S100A9;C8A;IGLV3-21;S100A8;C1QC;CFI;C3;IGHA1;C5;C1S;C4B;C8G;C4BPA;PGLYRP2;C8B;C1QB;C1R;CLU;IGHM;FGA;FCN3;CFH;CFB;IDO1;IGKV1-17 GO:0031100| organ regeneration APOA1;PPARG;APOA2 GO:0042593| glucose homeostasis INS;CNR1;TRPV4;PPARG GO:0043085| positive regulation of catalytic activity SOD1;AGT;MT3;APOA2 GO:0006820| anion transport VDAC1;GLRA1 GO:0007605| sensory perception of sound GPX1;SOD1 GO:0008202| steroid metabolic process HMGCR;CYP3A7;APOL1;CYP1A2;CYP3A4;CYP1B1;APOBR;CYP2D6;APOA1;CYP2C19;CYP17A1;CYP3A5;APOE;CYP1A1;CYP2C9 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4;PDCD6;TP53 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;MDM2 GO:0042554| superoxide anion generation SOD1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;APP;BDKRB1;APOE;APOA1;F2;KNG1;HTR2A;C3;GPR12;CNR1;APLP2;GPR55;C5;HTR1A;OPRD1;OPRM1;CNR2;INS;AGT GO:0098815| CHRNA7;APP GO:0032355| response to estradiol stimulus CAT;AGT;ESR1;CYP1A2;PTGS2 GO:0009611| response to wounding CYP1A1;FN1;F2;GPX1 GO:0035025| positive regulation of Rho protein signal transduction GPR55;GPR18;APOA1 GO:0006810| transport TRPV2;TTR;TRPV1;CACNA1I;ABCG2;ABCC1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade AGT;INS;CAT;F2 GO:0007568| aging TP53;KRT14;KRT16;CYP1A1;AGT;CAT;HMGCR;PTGS2;GSN;HTR2A;SOD1;CNR1;NAPEPLD GO:0015909| long-chain fatty acid transport PPARG;APOE GO:0071456| cellular response to hypoxia SLC29A1;MT3;P4HB;PTGS2;OPRD1;MDM2;TP53 GO:0097756| INS;PTGS2;HMGCR GO:0030595| leukocyte chemotaxis S100A9;CNR2 GO:0010468| regulation of gene expression TP73;F2;APOE;MDM2;APP;CYP1A2 GO:0007283| spermatogenesis CNR1;SOD1 GO:0001666| response to hypoxia CYP1A1;CAT;MT3;CHRNA7 GO:0002674| negative regulation of acute inflammatory response INS;APCS;PPARG GO:0010628| positive regulation of gene expression MT3;INS;GSN;TRPV4;APP;TP53;MDM2;CLU;FN1 GO:0007202| activation of phospholipase C activity GPR55;HTR2A;AGT GO:0046688| response to copper ion SOD1;AANAT GO:0010977| negative regulation of neuron projection development TRPV4;APOE;MDM2 GO:0032460| negative regulation of protein oligomerization INS;OPRD1 GO:0015758| glucose transport INS;PLA2G1B GO:0031000| response to caffeine HDAC1;PPARG;TP53 GO:0051262| protein tetramerization HMGCR;CAT;APP;TP53;TP73 GO:0045892| negative regulation of transcription, DNA-dependent TP53;MDM2;HDAC1;HDAC4;PPARG;ENO1;MT3 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;APOA1 GO:0071356| cellular response to tumor necrosis factor TRPV1;HDAC4;HDAC1 GO:0048511| rhythmic process AANAT;PPARG;HDAC1;TP53 GO:0043407| negative regulation of MAP kinase activity HMGCR;APOE;SMPD1 GO:0046716| muscle cell homeostasis ALDOA;SOD1 GO:0048714| positive regulation of oligodendrocyte differentiation PPARG;HDAC1;ASPA;TP73 GO:2000463| positive regulation of excitatory postsynaptic membrane potential APP;CHRNA7 GO:0034220| ion transmembrane transport TRPA1;GLRA1;TRPV1;GLRB;GLRA3;CHRNA7 GO:0051591| response to cAMP NME1;AANAT GO:0043200| response to amino acid stimulus GLRA3;GLRB;TP53 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0001541| ovarian follicle development SOD1 GO:0042744| hydrogen peroxide catabolic process PRDX1;HBB;HBA1;APOA4;CAT;GPX1 GO:0031532| actin cytoskeleton reorganization S100A9;TRPV4 GO:0045766| positive regulation of angiogenesis CYP1B1;PDCD6;CHRNA7;C5;C3 GO:0006915| apoptotic process SIVA1;MT3;GPX1;S100A8;GSN;S100A9;PARP1;TP73;VDAC1;PDCD6;APLP1;CLU;TP53;APP GO:0050714| positive regulation of protein secretion FGA;PLA2G1B GO:0042220| response to cocaine SMPD1;MDM2;CNR1;OPRM1 GO:0030855| epithelial cell differentiation PPARG;KRT14;VDAC1 GO:0000187| activation of MAPK activity C5;SOD1;CHRNA7;APP;TP73;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade S100A7;APP;ALOX15;TRPV4;FGA;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;MT3 GO:0055085| transmembrane transport ABCG2;TRPM8;APOA1;VDAC1;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0009612| response to mechanical stimulus BDKRB1;PSPH;PPARG;TRPV4 GO:0035722| interleukin-12-mediated signaling pathway SOD1;P4HB;CA1 GO:0043066| negative regulation of apoptotic process TP53;MDM2;MMP9;HDAC1;GPX1;MT3;CAT;HMGCR;PTGS2;SOD1;MGMT GO:0001822| kidney development TP73;CAT;AGT GO:0042311| vasodilation GPX1;AGT;KNG1;APOE GO:1902177| SOD1 GO:0032259| methylation MGMT;CYP1A2 GO:0009615| response to virus CYP1A1;CLU;ENO1 GO:0008284| positive regulation of cell proliferation MDM2;HDAC4;FN1;HDAC1;F2;PTGS2;HMGCR;KRT6A;HTR1A;HTR2A;IL3;AGT;INS;CHRNA7 GO:0007340| acrosome reaction GLRA1;GLRB GO:0007218| neuropeptide signaling pathway GLRA1;GLRB;GLRA3;OPRD1;CPE;OPRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TP73;PPARG;HDAC4;HDAC1;TP53;APP;ESR1;PARP1 GO:0007626| locomotory behavior APP;SOD1;OPRM1 GO:0046677| response to antibiotic SOD1;CYP1A1;MDM2;TP53 GO:0002576| platelet degranulation FN1;SERPINA4;ALDOA;CLU;ORM2;APP;ITIH3;AHSG;APOA1;SERPINA3;A1BG;FGA;KNG1;ITIH4;APLP2;SOD1;TF;A2M;SERPINA1 GO:0043312| neutrophil degranulation AHSG;DSP;SERPINA3;A1BG;HBB;MMP9;EEF1A1;S100A7;ALDOA;ORM2;SERPINA1;KRT1;TTR;CAT;JUP;HRNR;ALOX5;C3;S100A9;GSN;S100A8 GO:0010288| response to lead ion CAT;APP GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;ENO1;TRPV4;TP73;TP53;APP;MDM2;HDAC1;PPARG;HDAC4;HDAC8;PARP1;ESR1 GO:0045087| innate immune response C4B;C8G;C4BPA;PGLYRP2;APCS;C4BPB;S100A9;C8A;F12;APOL1;S100A8;C1QC;CFI;C3;IGHA1;C5;C1S;FGA;FCN3;CFH;JCHAIN;CFB;C8B;C1QB;APP;C1R;CLU;IGHM;S100A7;KRT16;PPARG GO:0007155| cell adhesion APP;APLP1;FN1;CYP1B1;IGFALS;VTN;JUP GO:0034097| response to cytokine stimulus TP53;AANAT;ITIH4;PTGS2 GO:0007628| adult walking behavior GLRB;GLRA1 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0007611| learning or memory APP;CHRNA7;CNR1 GO:0030308| negative regulation of cell growth PPARG;TP53;BDKRB1;ENO1;MT3;AGT GO:0000302| response to reactive oxygen species SOD1;GPX1;CAT;APOE;S100A7;PRDX1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;S100A8;OPRM1;CYP1A1;S100A7;HDAC1;BDKRB1;IDO1 GO:0001508| regulation of action potential CACNA1G;GLRA1 GO:0008203| cholesterol metabolic process APP;APOA2;APOA4;APOE;APOA1;APOBR;HMGCR;APOL1;PON1;CAT GO:0007612| learning PTGS2;APP;VDAC1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;AGT;JUP GO:0042060| wound healing TP53;FN1;ALOX15;DSP;S100A8;OPRM1;GSN;KRT6A;INS GO:0071333| cellular response to glucose stimulus SLC29A1;NME1 GO:0030317| sperm motility CACNA1I;GAPDHS GO:0001660| fever generation IL3;TRPV1 GO:1905906| APP;APOE;CHRNA7 GO:0014824| artery smooth muscle contraction HTR2A;AGT GO:0046330| positive regulation of JNK cascade APP;TRPV4 GO:0043542| endothelial cell migration CYP1B1;S100A2 GO:0006695| cholesterol biosynthetic process APOA1;APOA4;HMGCR GO:0034599| cellular response to oxidative stress MGMT;SOD1;P4HB;PARP1;CAT;MT3;CCS;GPX1;HDAC1;GSR;PRDX1 GO:0033344| cholesterol efflux APOA1;ABCG2;APOA2;APOE;APOA4 GO:0071230| cellular response to amino acid stimulus GLRA1 GO:0032526| response to retinoic acid PPARG;TP53 GO:0097332| SOD1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;CHRNA7;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1;AGT GO:0019372| lipoxygenase pathway PTGS2;PON1;ALOX5;GPX1;ALOX15 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;HDAC4 GO:0010243| response to organic nitrogen TP53;TP73;TRPV1;PTGS2 GO:0050728| negative regulation of inflammatory response APOA1;APOE;KRT1;CNR2 GO:0034465| response to carbon monoxide SOD1 GO:0006801| superoxide metabolic process CCS;SOD1 GO:0055093| response to hyperoxia CYP1A1;HDAC1;TP53;CAT GO:0051897| positive regulation of protein kinase B signaling cascade APP;INS;GPX1 GO:0060326| cell chemotaxis ABCC1;C5 GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0043278| response to morphine OPRM1;CNR1;MDM2 GO:0016525| negative regulation of angiogenesis PPARG;AGT GO:0007015| actin filament organization TRPV4;PLA2G1B;ALDOA GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0007517| muscle organ development CACNA1H;UTRN GO:0045893| positive regulation of transcription, DNA-dependent TP53;HDAC4;PPARG;HDAC1;TP73;ESR1;AGT;MT3 GO:0006631| fatty acid metabolic process PTGS2;C3;PTGS1;ALOX15 GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;MDM2;MGMT GO:0030593| neutrophil chemotaxis S100A8;S100A9;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent TP53;HDAC4;PPARG;EEF1A1;HDAC1;TP73;ENO1;PARP1;ESR1;INS;HDAC8 GO:0010666| positive regulation of cardiac muscle cell apoptosis AGT;HMGCR GO:0042493| response to drug CYP1A2;PTGS2;MGMT;HTR2A;SOD1;CAT;NME1;MDM2;SMPD1;TP53;APOA2;ABCC1;HDAC4;PPARG;CYP1A1;HDAC1;TRPA1;TP73;ABCG2;APOA1 GO:0050830| defense response to Gram-positive bacterium PGLYRP2;DCD;KRT6A;PLA2G1B;APP GO:0018158| protein oxidation GPX1;APOA1;APOA2 GO:0050905| neuromuscular process GLRA1;GLRB GO:0055114| oxidation-reduction process HMGCR;CYP3A7;PTGS2;P4HB;CYP1A2;SOD1;CYP3A4;CCS;GPX1;CP;ALOX5;PTGS1;ADH1C;CAT;PDIA3;GAPDHS;CRYZ;CYP1A1;CYP2C9;CYP1B1;PRDX1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5 GO:0007569| cell aging TP53;SOD1 GO:0050884| neuromuscular process controlling posture GLRA1 GO:0050808| synapse organization CHRNA7;APP GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0019731| antibacterial humoral response IGHA1;PLA2G1B;JCHAIN;APP;SEMG1;IGHM GO:0051702| interaction with symbiont FN1;GPX1 GO:1902176| INS;GPX1 20782:[DB14011 DB01119] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0086002| ATP1A1;CACNA1G GO:0055085| transmembrane transport SLC12A3;TRPV2;KCNMA1;KCNJ11;TRPV3;CACNA1H;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G GO:0034220| ion transmembrane transport TRPA1;GLRA1;GLRB;TRPV1;GLRA3;ATP1A1;CHRNA7 GO:0010033| response to organic substance CA2;CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;GLUL GO:0071356| cellular response to tumor necrosis factor TRPV1;KCNJ11 GO:0001666| response to hypoxia KCNMA1;CAT;CHRNA7;CYP1A1 GO:0006810| transport TRPV2;SLC12A3;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;KCNJ11;CAT GO:0042391| regulation of membrane potential GLRA1;CACNA1G;GLRB;KCNJ11;KCNMA1;CACNA1H GO:0051260| protein homooligomerization ACAT1;GLUL;GLRA3;GLRA1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;KCNJ11;ATP1A1;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0034465| response to carbon monoxide SOD1;KCNMA1 GO:0071333| cellular response to glucose stimulus KCNJ11;SLC29A1 GO:0035722| interleukin-12-mediated signaling pathway SOD1;CA1 GO:0001822| kidney development CA2;CAT GO:0008283| cell proliferation CYP1A1;GPX1;GLUL;HTR1A GO:0006811| ion transport TRPM8;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;SLC12A3;KCNJ11;KCNMA1;ATP1A1;GLRA3;CACNA1H;TRPV3 GO:0008217| regulation of blood pressure PTGS2;SOD1;ATP1A1;PTGS1;PPARG GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0050796| regulation of insulin secretion KCNJ11;CNR1 GO:0060083| smooth muscle contraction involved in micturition KCNMA1;TRPV1 GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;KCNMA1;KCNJ11 GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:1902476| GLRA3;SLC12A3;GLRA1;GLRB GO:0051592| response to calcium ion KCNMA1;AANAT GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SLC12A3;CACNA1H GO:0006970| response to osmotic stress TRPV4;KCNMA1 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1;KCNMA1 20783:[DB14011 DB05490] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05490|T131 PPARG common genes PPARG common pathways GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0015909| long-chain fatty acid transport PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4 GO:0045087| innate immune response PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0042493| response to drug SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;HMGCR;CNR1 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7;GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;AANAT;ACAT1 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG 20784:[DB14011 DB01671] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01671|4-(Hydroxymercury)Benzoic Acid CA2 common genes common pathways GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CA2;PTGS2;CYP1A2;SOD1 20785:[DB14011 DB04552] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes PTGS1;PLA2G1B;PTGS2 common pathways GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;UGT1A9;CNR1;HMGCR GO:0007566| embryo implantation SOD1;PTGS2 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0007613| memory PTGS2;CNR1;HTR2A;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0034765| regulation of ion transmembrane transport CACNA1H;CACNA1I;CLCNKA;CACNA1G GO:0006821| chloride transport GLRB;CLCNKA;GLRA1;GLRA3 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0050482| arachidonic acid secretion PLA2G4A;PLA2G1B GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;CLCNKA GO:0033280| response to vitamin D PTGS2 GO:0009395| phospholipid catabolic process NAPEPLD;PLA2G4A GO:0002227| innate immune response in mucosa PLA2G1B GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;AANAT;PTGS2;CYP1A2 GO:0046470| phosphatidylcholine metabolic process PLA2G1B GO:0044240| multicellular organismal lipid catabolic process PLA2G1B GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0045740| positive regulation of DNA replication PLA2G1B GO:0048146| positive regulation of fibroblast proliferation PLA2G1B GO:0061844| PLA2G1B GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0036150| PLA2G4A;PLA2G1B GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0036149| PLA2G1B;PLA2G4A GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain TRPV1;TRPA1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;UGT1A9;CYP2C9 GO:0035556| intracellular signal transduction PLA2G1B GO:0008152| metabolic process ACAT1;PLA2G4A;SMPD1;UGT1A9 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0036148| PLA2G4A;PLA2G1B GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;SLC16A1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG;PLA2G4A GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;CNR2;PTGS2;PTGS1;ALOX5 GO:0010942| positive regulation of cell death PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B GO:1902476| GLRA3;GLRB;CLCNKA;GLRA1 GO:0032637| interleukin-8 production PLA2G1B GO:0071498| cellular response to fluid shear stress PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0002446| neutrophil mediated immunity PLA2G1B GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0006810| transport TRPV2;ABCC1;CLCNKA;TRPV1;CACNA1I;ABCG2 GO:0007568| aging CYP1A1;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD GO:0042593| glucose homeostasis CNR1;SLC16A1;PPARG;TRPV4 GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A9;CYP1A1;CYP2C9;CYP2D6;CYP2C19 GO:0036152| PLA2G1B;PLA2G4A GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0016042| lipid catabolic process NAPEPLD;PLA2G1B;DAGLA;PLA2G4A GO:0034220| ion transmembrane transport TRPA1;GLRA1;CLCNKA;GLRB;TRPV1;GLRA3;CHRNA7 GO:0055085| transmembrane transport SLC16A1;TRPV2;SLC16A7;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;CACNA1I;TRPV4;VDAC1;CLCNKA;TRPA1;CACNA1G;ABCC1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0000187| activation of MAPK activity PLA2G1B;CHRNA7;SOD1 GO:0050714| positive regulation of protein secretion PLA2G1B GO:0032431| activation of phospholipase A2 activity PLA2G1B GO:0050778| positive regulation of immune response PLA2G1B GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0015758| glucose transport PLA2G1B GO:0006644| phospholipid metabolic process PLA2G4A;PLA2G1B;NAPEPLD GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1 GO:0010524| positive regulation of calcium ion transport into cytosol PLA2G1B GO:0042127| regulation of cell proliferation PLA2G4A;PTGS1;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0071318| cellular response to ATP TRPV1;SOD1;PTGS2 GO:0036151| PLA2G4A;PLA2G1B GO:0071284| cellular response to lead ion PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLA2G4A GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0030593| neutrophil chemotaxis PLA2G1B GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 GO:0050830| defense response to Gram-positive bacterium PLA2G1B GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0032094| response to food CYP1A1;OPRM1;SLC16A1 GO:0071407| cellular response to organic cyclic compound SLC16A1;CYP1B1;CYP1A1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9;ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0019731| antibacterial humoral response PLA2G1B GO:0019369| arachidonic acid metabolic process CYP1B1;DAGLA;CYP2D6;ALOX15;PLA2G4A;FAAH GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;GPX1;ALOX5 GO:0009750| response to fructose stimulus PTGS2 GO:0007015| actin filament organization TRPV4;PLA2G1B 20786:[DB14011 DB11217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11217|Arbutin TYR;ALB common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;TYR GO:0007601| visual perception TYR;CYP1B1;GLRB;CRYZ;GLRA1 GO:0009411| response to UV TYR;CAT GO:0033280| response to vitamin D TYR;PTGS2 GO:0008283| cell proliferation TYR;GPX1;HTR1A;CYP1A1 GO:0001895| retina homeostasis ALB;SOD1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0055114| oxidation-reduction process GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9;TYR;CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0098869| CAT;GPX1;PTGS1;PTGS2;ALB;GSR GO:0048538| thymus development SOD1;TYR GO:0051591| response to cAMP TYR;AANAT 20787:[DB14011 DB03967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03967|Dodecyl sulfate LYZ common genes common pathways GO:0006954| inflammatory response TRPV1;LYZ;ALOX15;IDO1;PTGS2;CNR2;PTGS1;ALOX5 GO:0008152| metabolic process SMPD1;LYZ;ACAT1 GO:0001895| retina homeostasis LYZ;SOD1 GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B GO:0043312| neutrophil degranulation LYZ;ALOX5;CAT 20788:[DB14011 DB03541] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0007568| aging CAT;HMGCR;PTGS2;CNR1;HTR2A;SOD1;NAPEPLD;CYP1A1;TYMS GO:0034097| response to cytokine stimulus TYMS;PTGS2;AANAT GO:0032259| methylation TYMS;CYP1A2 GO:0007623| circadian rhythm TYMS;AANAT GO:0033189| response to vitamin A PPARG;CYP1A1;TYMS;CAT GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;DHRS4L1;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;NQO2;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;TRPA1;CYP1A1;TYMS;PPARG;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0022900| electron transport chain CYP1A2;NQO2;GSR;IDO1 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0015949| nucleobase-containing small molecule interconversion TYMS;GSR GO:0014070| response to organic cyclic compound CYP1A1;TYMS;PPARG;TRPA1;PTGS2;CYP1A2;AANAT;ACAT1 GO:0009636| response to toxin TYMS;CYP1A1;CYP1B1;CAT;GPX1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;NQO2;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0045471| response to ethanol TYMS;SOD1;CNR1;HMGCR;OPRM1;CAT 20789:[DB14011 DB00138] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00138|Cystine SLC7A11;CTNS;SLC7A9;SLC3A1;SLC16A10 common genes common pathways GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;SLC7A11;PTGS2;SOD1 GO:0055085| transmembrane transport TRPM8;ABCG2;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G;TRPV2;CTNS;SLC16A10;TRPV3;CACNA1H GO:0007628| adult walking behavior GLRA1;GLRB;CTNS GO:0035094| response to nicotine CNR1;SLC7A11;CHRNA7 GO:0007420| brain development SLC7A11;CTNS;ACAT1 GO:0050890| cognition CHRNA7;CTNS GO:0006749| glutathione metabolic process GPX1;CTNS;SOD1;GSR GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT;SLC7A11 GO:0006811| ion transport CTNS;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1 GO:0008542| visual learning CTNS;HMGCR 20790:[DB14011 DB05992] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05992|Plinabulin TNF common genes common pathways GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;TNF;PPARG GO:0009615| response to virus TNF;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;TNF GO:0071407| cellular response to organic cyclic compound TNF;CYP1A1;CYP1B1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TNF;TRPV1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;TNF;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B;TNF GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0010033| response to organic substance TNF;TRPA1;CYP1A1;PPARG;SOD1;CYP1A2;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;TNF GO:0010628| positive regulation of gene expression TNF;TRPV4 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation CNR1;PTGS2;TNF GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;TNF;SMPD1 GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0010629| negative regulation of gene expression TNF;OPRD1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;TNF;CAT GO:0006954| inflammatory response TNF;TRPV1;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0006955| immune response TNF;OPRD1;CNR2 GO:0050796| regulation of insulin secretion TNF;CNR1 GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;OPRD1;PTGS2 GO:0001819| positive regulation of cytokine production SOD1;TNF GO:0006919| activation of caspase activity PPARG;TNF 20791:[DB14011 DB01010] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01010|Edrophonium ACHE;BCHE common genes common pathways GO:0008283| cell proliferation CYP1A1;HTR1A;ACHE;GPX1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;BCHE;PPARG GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0042136| neurotransmitter biosynthetic process ACHE;DAGLA GO:0007399| nervous system development GLRB;SMPD1;ACHE GO:0050714| positive regulation of protein secretion ACHE;PLA2G1B GO:0051262| protein tetramerization CAT;ACHE;HMGCR GO:0009611| response to wounding CYP1A1;GPX1;ACHE GO:0007517| muscle organ development CACNA1H;ACHE GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;BCHE;TRPA1;CYP1A1;PPARG;ABCG2 GO:0007612| learning PTGS2;VDAC1;BCHE GO:0007155| cell adhesion ACHE;CYP1B1 20792:[DB14011 DB04310] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;PDF 20793:[DB14011 DB06333] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06333|Trodusquemine PTPN1;SLC6A3;SLC6A2 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2 GO:0042053| regulation of dopamine metabolic process SLC6A3;HTR1A GO:0034976| response to endoplasmic reticulum stress ALOX15;PTPN1 GO:0007268| synaptic transmission OPRD1;OPRM1;GLRA3;HTR2A;SLC6A2;CACNA1G;GLRA1;VDAC1;GLRB GO:0007595| lactation SLC29A1;SLC6A3 GO:0045471| response to ethanol SLC6A3;CAT;HMGCR;OPRM1;CNR1;SOD1 GO:0042136| neurotransmitter biosynthetic process SLC6A3;DAGLA GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;SLC6A3;TRPM8;CACNA1G;ABCC1;SLC6A2;TRPA1 GO:0042220| response to cocaine SMPD1;SLC6A3;CNR1;OPRM1 GO:0031532| actin cytoskeleton reorganization TRPV4;PTPN1 GO:0051591| response to cAMP AANAT;SLC6A3 GO:0043407| negative regulation of MAP kinase activity PTPN1;SMPD1;HMGCR GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;SLC6A3;CYP1A1 GO:0006810| transport ABCG2;CACNA1I;TRPV1;ABCC1;SLC6A2;TRPV2 GO:0042493| response to drug ABCC1;SMPD1;SLC6A2;TRPA1;CYP1A1;PPARG;SLC6A3;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0048265| response to pain TRPA1;SLC6A2;TRPV1 GO:0035094| response to nicotine CNR1;CHRNA7;SLC6A3 GO:0007626| locomotory behavior SLC6A3;OPRM1;SOD1 20794:[DB14011 DB08479] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0032259| methylation CYP1A2;TYMS GO:0034097| response to cytokine stimulus AANAT;PTGS2;TYMS GO:0007623| circadian rhythm TYMS;AANAT GO:0033189| response to vitamin A CAT;PPARG;TYMS;CYP1A1 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;TYMS;PPARG;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0007568| aging CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CYP1A1;TYMS GO:0045471| response to ethanol CAT;OPRM1;HMGCR;CNR1;SOD1;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0009636| response to toxin CYP1A1;TYMS;CYP1B1;GPX1;CAT GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;PPARG;TYMS;CYP1A1 GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS 20795:[DB14011 DB02757] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02757|Pyrazole ADH1C;ESR1;ESR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;TRPV4;TRPV1;PPARG;ESR1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP2C9;CYP1A1;GPX1;ALOX5;PTGS1;ADH1C;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;ESR1 GO:0032355| response to estradiol stimulus CAT;ESR1;CYP1A2;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0006351| transcription, DNA-dependent ESR1;ESR2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0007165| signal transduction PLA2G1B;CACNA1I;ESR2;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;ESR1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;OPRM1;HTR2A;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus PPARG;ESR1 20796:[DB14011 DB02108] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02108|2-Aminoethanimidic Acid CTSB common genes common pathways GO:0043312| neutrophil degranulation CTSB;CAT;ALOX5 GO:0046697| decidualization CTSB;PTGS2 GO:0030855| epithelial cell differentiation VDAC1;CTSB;PPARG GO:0046718| entry of virus into host cell HTR2A;CTSB 20797:[DB14011 DB01695] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01695|N-Hydroxy-4-Phosphono-Butanamide TPI1 common genes common pathways GO:0008152| metabolic process SMPD1;TPI1;ACAT1 20798:[DB14011 DB01525] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01525|Ecgonine BCHE common genes common pathways GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0042493| response to drug BCHE;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;BCHE;OPRM1;PTGS2 20799:[DB14011 DB01035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes CYP2D6 common pathways GO:0086015| CACNA1G;SCN5A GO:0032259| methylation CYP1A2;DNMT1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;DNMT1 GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;DNMT1;PTGS2 GO:0007269| neurotransmitter secretion SLC22A2;NAAA GO:0086016| CACNA1G;SCN5A GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0071230| cellular response to amino acid stimulus GLRA1;DNMT1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;ALOX15;CYP2D6;DAGLA;CYP1B1 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;BCHE;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;DNMT1 GO:0055114| oxidation-reduction process CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;GLRB;GLRA1;CACNA1G GO:0051260| protein homooligomerization GLRA1;SLC22A1;GLRA3;ACAT1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1 GO:0010468| regulation of gene expression CYP1A2;DNMT1 GO:0010628| positive regulation of gene expression TRPV4;DNMT1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;DNMT1 GO:0009822| alkaloid catabolic process CYP3A4;CYP3A5;CYP2D6 GO:0034220| ion transmembrane transport TRPV1;GLRB;GLRA1;TRPA1;CHRNA7;SLC22A4;GLRA3 GO:0086002| CACNA1G;SCN5A GO:0055085| transmembrane transport SLC47A2;SCN5A;SLC47A1;TRPV2;SLC22A5;SLC22A4;TRPV3;KCNH2;CACNA1H;SLC22A3;SLC22A2;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;SLC22A1;CACNA1G GO:0042136| neurotransmitter biosynthetic process SLC22A2;DAGLA GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;NAAA;PTGS1;GPX1 GO:0002027| regulation of heart rate SCN5A;CACNA1G GO:0086091| CACNA1G;KCNH2;SCN5A GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0019228| regulation of action potential in neuron CACNA1G;CACNA1I;CACNA1H;SCN5A GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SCN5A;CACNA1H GO:0051100| negative regulation of binding CYP2D6 GO:0006351| transcription, DNA-dependent PPARG;DNMT1 GO:0071277| cellular response to calcium ion ALOX15;SCN5A GO:0086010| KCNH2;CACNA1H;SCN5A;CACNA1G;CACNA1I GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H;KCNH2;SCN5A GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0006641| triglyceride metabolic process GPX1;CAT;SLC22A4 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN5A GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCHE;PPARG;CYP1B1 GO:0086046| CACNA1G;SCN5A GO:0006812| cation transport TRPM8;SLC22A2;SLC22A1 GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0006811| ion transport SLC22A5;GLRA3;SLC22A3;CACNA1H;KCNH2;TRPV3;SLC22A4;SCN5A;CHRNA7;TRPV2;TRPA1;GLRA1;CACNA1G;SLC22A1;TRPM8;SLC22A2;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I GO:0086045| CACNA1G;SCN5A GO:0006855| drug transmembrane transport SLC22A5;SLC22A3;SLC47A2;SLC47A1;ABCC1;SLC22A1;ABCG2;SLC22A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 20800:[DB14011 DB11591] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;SLCO2B1;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;ABCB5;CACNA1H;SLCO1A2;TRPV3 GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;HRH1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PPARG;GPR18 GO:0042391| regulation of membrane potential GLRA1;CACNA1G;GLRB;CACNA1H;ABCB5 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;HTR2A GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB5 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;SLCO2B1;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I;GLRA3;SLCO1A2;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0042908| xenobiotic transport ABCB5;ABCG2;ABCC1 GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2;HRH1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;HRH1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;HRH1 GO:0008542| visual learning HMGCR;HRH1 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;HRH1;PTGS2;CNR2;ALOX5;PTGS1 20801:[DB14011 DB01810] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01810|[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways 20802:[DB14011 DB05352] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05352|Fx-1006A TTR common genes common pathways GO:0043312| neutrophil degranulation TTR;CAT;ALOX5 GO:0006810| transport TRPV2;TTR;TRPV1;CACNA1I;ABCG2;ABCC1 GO:0042572| retinol metabolic process CYP1B1;TTR GO:0001523| retinoid metabolic process TTR;NAPEPLD 20803:[DB14011 DB06775] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06775|Carglumic acid CPS1 common genes common pathways GO:0032496| response to lipopolysaccharide CPS1;CYP1A2;OPRM1;PTGS2;CNR2;CNR1;CYP1A1;IDO1 GO:0042311| vasodilation CPS1;GPX1 GO:0042594| response to starvation PPARG;CPS1;ACAT1 GO:0042493| response to drug SOD1;HTR2A;CPS1;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2 GO:0032094| response to food CYP1A1;OPRM1;CPS1 GO:0051591| response to cAMP CPS1;AANAT GO:0043200| response to amino acid stimulus GLRB;GLRA3;CPS1 GO:0001889| liver development ACAT1;CPS1;CYP1A1 GO:0008152| metabolic process SMPD1;CPS1;ACAT1 GO:0071320| cellular response to cAMP AANAT;CPS1 GO:0051384| response to glucocorticoid stimulus CPS1;PTGS2 GO:0009636| response to toxin GPX1;CAT;CPS1;CYP1B1;CYP1A1 GO:0010043| response to zinc ion AANAT;CPS1 GO:0070365| hepatocyte differentiation CYP1A1;CPS1 20804:[DB14011 DB05969] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0030324| lung development VEGFA;CYP1A2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;VEGFA GO:0002576| platelet degranulation SOD1;VEGFA GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;CDK7;PPARG;PLA2G1B GO:0001822| kidney development CAT;VEGFA GO:0043066| negative regulation of apoptotic process SOD1;VEGFA;PTGS2;HMGCR;CAT;GPX1 GO:0030224| monocyte differentiation PPARG;VEGFA GO:0006355| regulation of transcription, DNA-dependent CDK7;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CDK7;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter CDK7;PPARG GO:0071456| cellular response to hypoxia SLC29A1;VEGFA;PTGS2;OPRD1 GO:0032793| positive regulation of CREB transcription factor activity VEGFA;OPRD1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;VEGFA;OPRM1;ALOX15;TRPV4 GO:0030855| epithelial cell differentiation VEGFA;VDAC1;PPARG GO:0001541| ovarian follicle development SOD1;VEGFA GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;VEGFA GO:0043406| positive regulation of MAP kinase activity HTR2A;VEGFA GO:0001666| response to hypoxia CAT;CHRNA7;VEGFA;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;VEGFA GO:0001525| angiogenesis CYP1B1;PTGS2;VEGFA GO:0048469| cell maturation VEGFA;PPARG GO:0006351| transcription, DNA-dependent CDK7;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter VEGFA;PPARG GO:0007399| nervous system development GLRB;SMPD1;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;VEGFA;PTGS2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;PTGS2 GO:0010629| negative regulation of gene expression OPRD1;VEGFA GO:0007595| lactation SLC29A1;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;HTR2A GO:0043117| positive regulation of vascular permeability TRPV4;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2;OPRD1 GO:0008283| cell proliferation CDK7;CYP1A1;HTR1A;GPX1 GO:0051781| positive regulation of cell division CAT;VEGFA 20805:[DB14011 DB00809] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways GO:0008016| regulation of heart contraction CHRM2;CACNA1H GO:0007166| cell surface receptor linked signaling pathway TRPA1;CHRM4;TRPV1 GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger CNR1;CHRM2 GO:0007399| nervous system development GLRB;SMPD1;CHRM3;CHRM2;CHRM1 GO:0050890| cognition CHRM1;CHRNA7 GO:0006939| smooth muscle contraction CHRM3;HTR2A GO:0007165| signal transduction OPRM1;CNR2;OPRD1;HTR1A;GPR55;CHRM1;CNR1;GPR12;HTR2A;CHRM2;CHRNA7;SMPD1;CHRM3;PPARG;GPR18;PLA2G1B;CACNA1I;CHRM4 GO:0008283| cell proliferation GPX1;CHRM1;HTR1A;CHRM4;CYP1A1;CHRM3 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;CHRM1;HMGCR;PTGS2 GO:0009615| response to virus CYP1A1;CHRM2 GO:0007186| G-protein coupled receptor signaling pathway CHRM4;GPR18;PPARG;CHRM3;HTR2A;CNR1;GPR12;CHRM2;GPR55;HTR1A;CHRM1;OPRD1;OPRM1;CNR2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRM1;CNR2;OPRD1;CNR1;CHRM2 20806:[DB14011 DB02047] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes PTGS1 common pathways GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9;ALOX5;PTGS1;GPX1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR GO:0006629| lipid metabolic process CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS1;ALOX5;CNR2;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 20807:[DB14011 DB04879] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;FLT4;KDR;TRPV4;ALOX15 GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7;FLT1 GO:0043406| positive regulation of MAP kinase activity FLT1;HTR2A GO:0048514| blood vessel morphogenesis CYP1B1;FLT4;FLT1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade FLT1;CAT;KDR GO:0046330| positive regulation of JNK cascade FLT4;TRPV4 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;FLT1;PTGS2;HMGCR;KDR;FLT4 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;FLT4;KDR GO:0001934| positive regulation of protein phosphorylation KDR;FLT4;CHRNA7 GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0016032| viral reproduction VDAC1;KDR;HTR2A GO:0001525| angiogenesis PTGS2;FLT1;FLT4;KDR;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1;FLT4 20808:[DB14011 DB02303] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;DPYD;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4 20809:[DB14011 DB00004] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;IL2RA;HTR1A GO:0065009| regulation of molecular function IL2RB;TRPV1;IL2RA;IL2RG GO:0007165| signal transduction CHRNA7;OPRD1;IL2RG;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;IL2RB;GPR18;PPARG GO:0016032| viral reproduction IL2RG;HTR2A;VDAC1;IL2RB GO:0006955| immune response IL2RG;OPRD1;CNR2;IL2RA GO:0006954| inflammatory response CNR2;PTGS2;IL2RA;ALOX5;PTGS1;IDO1;ALOX15;TRPV1 GO:0007166| cell surface receptor linked signaling pathway IL2RA;TRPA1;TRPV1 GO:0006915| apoptotic process IL2RA;GPX1;VDAC1 GO:0042130| negative regulation of T cell proliferation IDO1;IL2RA GO:0002376| immune system process IDO1;IL2RA GO:0050728| negative regulation of inflammatory response CNR2;IL2RA GO:0043066| negative regulation of apoptotic process IL2RB;CAT;GPX1;SOD1;PTGS2;HMGCR 20810:[DB14011 DB05461] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0007565| female pregnancy IDO1;ADRA2B;ADRA2C GO:0042310| vasoconstriction HTR1A;HTR2B GO:0007507| heart development HTR2B;PPARG GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1 GO:0045777| positive regulation of blood pressure CNR1;ADRA2B GO:0051781| positive regulation of cell division CAT;HTR2B GO:0050796| regulation of insulin secretion CNR1;ADRA2C GO:0001819| positive regulation of cytokine production HTR2B;SOD1 GO:0045907| positive regulation of vasoconstriction HTR2A;ADRA2C;PTGS2 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;HTR2B GO:0006939| smooth muscle contraction HTR2B;HTR2A GO:0007165| signal transduction PLA2G1B;CACNA1I;HTR2B;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;ADRA2B;HTR1A;GPR55;ADRA2C GO:0007610| behavior HTR2B;HTR1A;HTR2A GO:0042493| response to drug TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2;HTR2B;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2B;HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;HTR2B GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;HTR2B GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;HTR2B GO:0050795| regulation of behavior HTR2B;HTR1A;HTR2A GO:0071502| cellular response to temperature stimulus TRPV1;HTR2B GO:0000187| activation of MAPK activity CHRNA7;ADRA2B;SOD1;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;HTR2B;ALOX15;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55 GO:0007202| activation of phospholipase C activity HTR2A;GPR55;HTR2B GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPA1;HTR2B;TRPV1 GO:0007186| G-protein coupled receptor signaling pathway HTR2B;GPR18;PPARG;ADRA2B;CNR1;GPR12;HTR2A;GPR55;HTR1A;ADRA2C;OPRD1;OPRM1;CNR2 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;TRPV4;TRPM8;HTR2B GO:0007210| serotonin receptor signaling pathway HTR2B;HTR1A;HTR2A 20811:[DB14011 DB04849] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04849|Cediranib KDR common genes common pathways GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;KDR GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;KDR GO:0045766| positive regulation of angiogenesis CHRNA7;KDR;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;OPRM1;HMGCR;GPR55;HTR2A;TRPV4;KDR;ALOX15 GO:0001525| angiogenesis PTGS2;KDR;CYP1B1 GO:0016032| viral reproduction VDAC1;KDR;HTR2A GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0010629| negative regulation of gene expression OPRD1;KDR 20812:[DB14011 DB02690] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02690|NU1025 PARP1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0034599| cellular response to oxidative stress GSR;GPX1;CAT;PARP1;SOD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;PPARG;PLA2G1B GO:0006915| apoptotic process VDAC1;GPX1;PARP1 GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0071294| cellular response to zinc ion GLRA1;PARP1 GO:0032869| cellular response to insulin stimulus PARP1;PLA2G1B;PPARG GO:0010332| response to gamma radiation PARP1;GPX1 20813:[DB14011 DB07312] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07312|2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE FBP1 common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;FBP1 GO:0051289| protein homotetramerization CAT;FBP1;TRPM8;TRPV1;CRYZ;TRPA1 GO:0030308| negative regulation of cell growth FBP1;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;TRPV4;TRPV1;PPARG 20814:[DB14011 DB01705] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01705|Bis(5-Amidino-Benzimidazolyl)Methane PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20815:[DB14011 DB02901] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes CYP17A1 common pathways GO:0008209| androgen metabolic process ESR1;CYP3A4;CYP19A1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0042448| progesterone metabolic process CYP17A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C2;ESR1;AR GO:0006351| transcription, DNA-dependent AR;ESR1;NR3C2;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;PPARG;CYP2C9;PTGS1;NAAA;GPX1;HSD17B1;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;CYP11A1 GO:0016125| sterol metabolic process CYP11A1;CYP19A1;CYP17A1;CYP1B1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006702| androgen biosynthetic process CYP17A1 GO:0007548| sex differentiation CYP17A1;AR GO:0008283| cell proliferation HTR1A;AR;GPX1;CYP1A1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;AR GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ESR1;HTR2A;OPRM1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0007165| signal transduction ESR1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;AR;CHRNA7;PPARG;GPR18;SMPD1;NR3C2;CACNA1I;PLA2G1B GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CYP19A1;CRYZ;CAT;PTGS1;ALOX5;GPX1;HSD17B1;CYP3A4;SOD1;CYP11A1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;PPARG GO:0022900| electron transport chain CYP1A2;CYP19A1;IDO1;GSR GO:0042493| response to drug ABCB1;ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;CYP1A2;PTGS2;HTR2A;SOD1 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C2;ESR1;AR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C2;ESR1;AR GO:0008210| estrogen metabolic process CYP1B1;HSD17B1 GO:0006694| steroid biosynthetic process CYP11A1;HMGCR;HSD17B1;CYP19A1;CYP17A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0008203| cholesterol metabolic process CAT;HMGCR;CYP11A1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;TRPV4;TRPV1 GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR;ESR1 GO:0055085| transmembrane transport ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H GO:0042446| hormone biosynthetic process CYP17A1 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1;CYP1A1 GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0006810| transport AR;TRPV2;ABCC1;ABCG2;TRPV1;ABCB1;CACNA1I GO:0010468| regulation of gene expression AR;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP11A1;CYP1A2;CYP3A7;HMGCR;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0006704| glucocorticoid biosynthetic process CYP17A1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TRPV1 20816:[DB14011 DB07100] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07100|4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;HSP90AA1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0046677| response to antibiotic SOD1;CYP1A1;HSP90AA1 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;HSP90AA1 GO:0009409| response to cold TRPM8;HSP90AA1;PPARG;TRPA1 GO:0009408| response to heat SOD1;TRPV3;TRPV2;HSP90AA1;TRPV1 20817:[DB14011 DB00163] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00163|Vitamin E NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;SEC14L4;SEC14L3;SEC14L2;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes SOD1;ALOX5 common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;NR1I2;PPARG;SMPD1;CHRNA7;PRKCB;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0009725| response to hormone stimulus ACAT1;GCLC GO:0060047| heart contraction GPX1;SOD1 GO:0048662| negative regulation of smooth muscle cell proliferation HMOX1;PPARG GO:0001819| positive regulation of cytokine production SOD1 GO:0050796| regulation of insulin secretion PRKCA;CNR1 GO:0032869| cellular response to insulin stimulus PPARG;GSTP1;PLA2G1B;GCLC GO:0002262| myeloid cell homeostasis SOD1 GO:0032502| developmental process CYP1A1;TTPA GO:0042908| xenobiotic transport ABCG2;ABCC1;NR1I2 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0040014| regulation of multicellular organism growth SOD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0045454| cell redox homeostasis GCLC;GPX1;GSR GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0043627| response to estrogen stimulus HMOX1;GSTM3;PPARG GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0007584| response to nutrient NQO1;TTPA;PPARG;HMGCR;CNR1;GCLC GO:1902042| HMOX1;GPX1 GO:0070301| cellular response to hydrogen peroxide NQO1;CYP1B1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2;HMOX1 GO:0002540| leukotriene production involved in inflammatory response ALOX5 GO:0014823| response to activity GCLC;CAT GO:0035865| cellular response to potassium ion SOD1;CACNA1H GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;HMOX1;SOD1 GO:0034976| response to endoplasmic reticulum stress PPP2CB;ALOX15 GO:0071276| cellular response to cadmium ion CYP1A2;HMOX1;SOD1 GO:0006749| glutathione metabolic process GSTA2;SOD1;GSTO1;GCLC;GPX1;GSTM3;GSR;GSTP1 GO:0001890| placenta development PPARG;TTPA;SOD1 GO:0042178| xenobiotic catabolic process CRYZ;GSTM3;GSTO1 GO:0033591| response to L-ascorbic acid GSTP1;CAT GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0001895| retina homeostasis SOD1 GO:0006809| nitric oxide biosynthetic process NQO1;CYP1B1 GO:0046620| regulation of organ growth SOD1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;NQO1;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin CYP1A1;NQO1;TTPA;CYP1B1;GSTP1;GPX1;CAT GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP2C9;PPARG;TTPA;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0042953| lipoprotein transport PRKCB;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2;GCLC GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;HMOX1;CNR1;SOD1;PTGS2 GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;HMOX1;TRPA1;PPP2CB GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;GSTP1;CYP1B1;CYP2C19;CYP2D6;CYP3A5;NR1I2;NQO1;CYP2C9 GO:0035556| intracellular signal transduction PRKCB;HMOX1;DGKA;PRKCA;PLA2G1B GO:0008152| metabolic process GSTP1;SMPD1;GSTM3;ACAT1;DGKA;GSTA2;GSTO1 GO:0001525| angiogenesis HMOX1;PTGS2;PRKCA;CYP1B1 GO:0045471| response to ethanol GSTP1;NQO1;CAT;OPRM1;HMGCR;CNR1;SOD1 GO:0043401| steroid hormone mediated signaling pathway NR1I2;PPARG GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;SEC14L2;PRKCB GO:0006357| regulation of transcription from RNA polymerase II promoter PRKCB;PPARG GO:0008090| retrograde axon cargo transport SOD1 GO:0000303| response to superoxide SOD1 GO:0019430| removal of superoxide radicals SOD1;NQO1 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;HMOX1 GO:0009268| response to pH TTPA;TRPV1 GO:1904706| HMOX1;PPARG;GSTP1 GO:0009408| response to heat TRPV1;GCLC;TRPV2;SOD1;TRPV3 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PRKCB;PLA2G1B GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0019226| transmission of nerve impulse SOD1 GO:0006816| calcium ion transport TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G;CHRNA7;TRPV2;PRKCB;TRPV3;CACNA1H GO:0043087| regulation of GTPase activity SOD1 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0019370| leukotriene biosynthetic process PLA2G1B;ALOX5 GO:0042738| exogenous drug catabolic process CYP2C19;NR1I2;CYP2C9;CYP3A4;CYP1A2 GO:0043524| negative regulation of neuron apoptosis SOD1;HMOX1;GCLC GO:0031667| response to nutrient levels SOD1;GSTP1 GO:0045859| regulation of protein kinase activity SOD1 GO:0007605| sensory perception of sound SOD1;GPX1 GO:0043085| positive regulation of catalytic activity SOD1 GO:0032720| negative regulation of tumor necrosis factor production GSTP1;GPR18;CHRNA7 GO:0051260| protein homooligomerization ACAT1;HMOX1;GLRA3;GLRA1 GO:0031100| organ regeneration PPARG;GSTP1 GO:0002376| immune system process IDO1;PRKCB GO:0048538| thymus development SOD1 GO:0006979| response to oxidative stress PTGS2;HMOX1;SOD1;GPX1;PTGS1;CAT;GCLC;NQO1 GO:0006874| cellular calcium ion homeostasis GPR12;HTR2A;CHRNA7;PRKCB;TRPM8;TRPV4 GO:0098869| PTGS2;GSTO1;GPX1;PTGS1;CAT;GSTP1;GSR GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2;HMOX1 GO:0010468| regulation of gene expression PPP2CB;CYP1A2 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1;CAT;GCLC;NQO1;CYP1A1 GO:0006810| transport TRPV2;ABCC1;TTPA;TRPV1;CACNA1I;ABCG2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;NQO1;GSTP1 GO:0042554| superoxide anion generation SOD1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;NR1I2;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0034605| cellular response to heat HMOX1;PTGS2;TRPV1;TRPV4 GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0046716| muscle cell homeostasis SOD1 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PPP2CA;SOD1;PTGS2;CYP1A2 GO:2001300| ALOX5 GO:0045892| negative regulation of transcription, DNA-dependent GCLC;PPARG;NR1I2 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT;PRKCB;HMOX1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0046688| response to copper ion SOD1;AANAT GO:0090212| negative regulation of establishment of blood-brain barrier TRPV1;TTPA GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0007283| spermatogenesis SOD1;CNR1 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;SEC14L2 GO:0070374| positive regulation of ERK1 and ERK2 cascade PRKCA;ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0006915| apoptotic process PPP2CA;VDAC1;PRKCA;HMOX1;PRKCB;GPX1 GO:0030855| epithelial cell differentiation GSTA2;PPARG;VDAC1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;PLA2G1B GO:0001541| ovarian follicle development SOD1 GO:0008219| cell death HMOX1;HTR2A GO:0045766| positive regulation of angiogenesis CYP1B1;PRKCA;PRKCB;CHRNA7;HMOX1 GO:0046686| response to cadmium ion CAT;GCLC GO:0043200| response to amino acid stimulus GSTP1;GLRB;GLRA3 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0007155| cell adhesion PRKCA;CYP1B1 GO:0043312| neutrophil degranulation ALOX5;CAT;GSTP1 GO:0046677| response to antibiotic PPP2CB;CYP1A1;SOD1 GO:0002576| platelet degranulation SOD1 GO:0007626| locomotory behavior OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NR1I2;PPARG GO:1902177| SOD1 GO:0032259| methylation CYP1A2;GSTO1 GO:0006654| phosphatidic acid biosynthetic process DGKA;PLA2G1B GO:0035722| interleukin-12-mediated signaling pathway SOD1;GSTA2;GSTO1 GO:0043066| negative regulation of apoptotic process CAT;GCLC;GPX1;SOD1;PTGS2;HMGCR;GSTP1;NQO1 GO:0034599| cellular response to oxidative stress GSR;GSTP1;SOD1;CAT;GPX1 GO:0097332| SOD1 GO:0071333| cellular response to glucose stimulus SLC29A1;GCLC GO:0000302| response to reactive oxygen species GSTP1;CAT;GPX1;SOD1 GO:0030308| negative regulation of cell growth PPP2CA;PPARG GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0009410| response to xenobiotic stimulus GPX1;GCLC GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR1I2 GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0035094| response to nicotine CHRNA7;CNR1;HMOX1 GO:0006801| superoxide metabolic process NQO1;SOD1 GO:0034465| response to carbon monoxide SOD1 GO:0019372| lipoxygenase pathway ALOX15;ALOX5;GPX1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;HMOX1 GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;NQO1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMOX1;GSTO1;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;GPX1;PTGS1 GO:0007569| cell aging SOD1 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0006355| regulation of transcription, DNA-dependent PRKCB;SEC14L2;PPARG;NR1I2;PPP2CA GO:0046685| response to arsenic-containing substance CYP1A1;GCLC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR1I2;SEC14L2 20818:[DB14011 DB03910] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03910|S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;PPARG;NOS3;CYP1B1 GO:0008217| regulation of blood pressure PPARG;NOS3;SOD1;PTGS2;PTGS1 GO:1902042| NOS3;GPX1 GO:0006809| nitric oxide biosynthetic process NOS3;CYP1B1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat TRPV1;NOS3;TRPV3;SOD1;TRPV2 GO:0001525| angiogenesis PTGS2;CYP1B1;NOS3 GO:0045776| negative regulation of blood pressure CNR1;NOS3 GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 GO:0055114| oxidation-reduction process GPX1;ALOX5;PTGS1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;NOS3;CYP2C9;CYP1A1;CRYZ GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0042311| vasodilation GPX1;NOS3 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0030324| lung development NOS3;CYP1A2 20819:[DB14011 DB06202] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes CNR2 common pathways GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;OPRD1;OPRM1;PTGS2;CNR2 GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG;ESR2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0006955| immune response CNR2;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG;ESR1 GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;PTGS2;CNR2;PTGS1;ALOX5 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;ESR1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;ESR2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;HTR2A;ESR1 GO:0001975| response to amphetamine CNR2;SOD1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0038171| CNR1;GPR55;CNR2 GO:0032229| negative regulation of synaptic transmission, GABAergic CNR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;CYP1A1;IDO1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2;ESR1 GO:0033004| negative regulation of mast cell activation CNR1;CNR2 GO:0050728| negative regulation of inflammatory response CNR2 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG;ESR2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0030595| leukocyte chemotaxis CNR2 GO:0045759| negative regulation of action potential CNR1;CNR2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0032355| response to estradiol stimulus CAT;ESR1;PTGS2;CYP1A2 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRM1;CNR2;OPRD1 GO:0051001| negative regulation of nitric-oxide synthase activity CNR1;CNR2 20820:[DB14011 DB05905] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05905|TD-2749 HTR4 common genes common pathways GO:0007268| synaptic transmission OPRD1;HTR4;OPRM1;GLRA3;HTR2A;CACNA1G;GLRA1;GLRB;VDAC1 GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;HTR4;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;HTR4;OPRM1;OPRD1;PPARG;GPR18 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger OPRD1;OPRM1;CNR2;HTR4;CNR1 20821:[DB14011 DB07477] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07477|Felbinac CTSL common genes common pathways 20822:[DB14011 DB07619] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07619|N-cyclopropyl-N-(trans-4-pyridin-3-ylcyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HMGCR;CYP3A7;CYP1A2;CYP3A4;HSD11B1;CYP1A1;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP17A1;CYP3A5 GO:0006704| glucocorticoid biosynthetic process HSD11B1;CYP17A1 GO:0030324| lung development HSD11B1;CYP1A2 GO:0055114| oxidation-reduction process HSD11B1;CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CYP1B1;CRYZ;CYP2C9;CYP1A1 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;HSD11B1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 20823:[DB14011 DB00807] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00807|Proparacaine SCN10A common genes common pathways GO:0034765| regulation of ion transmembrane transport CACNA1I;SCN10A;CACNA1G;CACNA1H GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CACNA1G;SCN10A;TRPA1;GLRA1;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPM8 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization CACNA1G;SCN10A GO:0019233| sensory perception of pain CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1;SCN10A;TRPA1;TRPV1 GO:0035725| sodium ion transmembrane transport CACNA1I;SCN10A;CACNA1G;CACNA1H GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1I;SCN10A;CACNA1G GO:0002027| regulation of heart rate CACNA1G;SCN10A GO:0007600| sensory perception OPRM1;TRPV2;SCN10A GO:0086010| CACNA1H;CACNA1I;CACNA1G;SCN10A GO:0055085| transmembrane transport TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;CACNA1G;SCN10A;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0086016| SCN10A;CACNA1G 20824:[DB14011 DB07784] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07784|[4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID IGKC common genes common pathways GO:0001895| retina homeostasis SOD1;IGKC GO:0006955| immune response IGKC;OPRD1;CNR2 GO:0002376| immune system process IDO1;IGKC GO:0045087| innate immune response PPARG;IGKC 20825:[DB14011 DB07121] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07121|4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;IDO1;CYP1A1;ADAM17 GO:0007155| cell adhesion ADAM17;CYP1B1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;ADAM17 GO:0050830| defense response to Gram-positive bacterium ADAM17;PLA2G1B GO:0042493| response to drug TRPA1;PPARG;ADAM17;CYP1A1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0002446| neutrophil mediated immunity PLA2G1B;ADAM17 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;ADAM17 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ADAM17 20826:[DB14011 DB01972] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0031100| organ regeneration ATIC;PPARG GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;DLG4 GO:0043406| positive regulation of MAP kinase activity PDE5A;HTR2A GO:0042130| negative regulation of T cell proliferation IDO1;PDE5A GO:0051262| protein tetramerization HMGCR;TGM3;CAT GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;DLG4;TRPV2 GO:0006915| apoptotic process GPX1;HINT1;VDAC1 GO:0007612| learning VDAC1;DLG4;PTGS2 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;GMPR;CYP1A1;CYP2C9 GO:0006355| regulation of transcription, DNA-dependent PPARG;HINT1 GO:0007165| signal transduction PPARG;GPR18;PDE5A;SMPD1;PLA2G1B;CACNA1I;DLG4;GPR55;HTR1A;HINT1;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;DLG4;TRPV1;TRPV4 GO:0015949| nucleobase-containing small molecule interconversion GUK1;GSR GO:0006139| nucleobase-containing compound metabolic process ATIC;SLC29A1 GO:0007399| nervous system development DLG4;GLRB;SMPD1 GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity OPRM1;DLG4 GO:0008152| metabolic process ATIC;PDE5A;SMPD1;ACAT1 GO:0009409| response to cold TRPM8;TRPA1;GMPR;PPARG GO:0006351| transcription, DNA-dependent PPARG;HINT1 GO:0007268| synaptic transmission DLG4;HTR2A;GLRA3;OPRM1;OPRD1;GLRA1;CACNA1G;VDAC1;GLRB 20827:[DB14011 DB05662] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05662|NP-50301 ESR1 common genes common pathways GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TRPV1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;TRPV1;TRPV4;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR1;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ESR1;HTR2A;OPRM1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;ESR1;HTR1A;GPR55;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;PPARG GO:0006351| transcription, DNA-dependent ESR1;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG 20828:[DB14011 DB02621] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02621|Latrunculin A ACTA1;GSN common genes common pathways GO:0007568| aging CAT;NAPEPLD;CNR1;HTR2A;SOD1;GSN;PTGS2;HMGCR;CYP1A1 GO:0006936| muscle contraction CACNA1H;ACTA1;GLRA1 GO:0006915| apoptotic process VDAC1;GPX1;GSN GO:0010628| positive regulation of gene expression GSN;ACTA1;TRPV4 GO:0048741| skeletal muscle fiber development GPX1;ACTA1 GO:0042060| wound healing ALOX15;GSN;OPRM1 GO:0009612| response to mechanical stimulus TRPV4;PPARG;ACTA1 GO:0043312| neutrophil degranulation CAT;ALOX5;GSN GO:0010226| response to lithium ion PTGS2;ACTA1 GO:0071276| cellular response to cadmium ion GSN;CYP1A2;SOD1 GO:0045471| response to ethanol SOD1;CNR1;HMGCR;OPRM1;GSN;CAT 20829:[DB14011 DB05511] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05511|Piclidenoson ADORA3 common genes common pathways GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;ADORA3;CAT GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;ADORA3;PPARG;CYP1B1 GO:0030336| negative regulation of cell migration CYP1B1;ADORA3 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7;SMPD1;PPARG;ADORA3;GPR18;CACNA1I;PLA2G1B GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ADORA3;ALOX5;PTGS1;CNR2;PTGS2 GO:0008016| regulation of heart contraction CACNA1H;ADORA3 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PPARG;GPR18;ADORA3 GO:0009611| response to wounding CYP1A1;ADORA3;GPX1 20830:[DB14011 DB06879] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways GO:0007623| circadian rhythm NOS2;AANAT GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;NOS2;CNR1;OPRM1;CYP1A2;PTGS2;CNR2 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CRYZ;NOS2;CYP1A1;CYP2C9;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045454| cell redox homeostasis NOS2;GSR;GPX1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS2 20831:[DB14011 DB07637] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07637|Dibromotyrosine EPOR common genes common pathways GO:0007507| heart development PPARG;EPOR GO:0007420| brain development EPOR;ACAT1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;EPOR;GPR12;CNR1;HTR2A;GPR55;HTR1A;CHRNA7 GO:0046697| decidualization EPOR;PTGS2 20832:[DB14011 DB03158] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;CHRNA7;INPP5B GO:0030317| sperm motility CACNA1I;INPP5B GO:0007283| spermatogenesis INPP5B;CNR1;SOD1 20833:[DB14011 DB05202] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways GO:0051260| protein homooligomerization ACAT1;GLRA3;VWF;GLRA1 GO:0009611| response to wounding VWF;GPX1;CYP1A1 GO:0002576| platelet degranulation VWF;SOD1 GO:0007155| cell adhesion VWF;CYP1B1;GP1BA GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;GP1BA 20834:[DB14011 DB00693] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00693|Fluorescein CYP1A1;SLC22A6;ABCB11;ABCC1 common genes CYP1A1;ABCC1 common pathways GO:0018894| dibenzo-p-dioxin metabolic process CYP1A1;CYP1A2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;IDO1;CYP1A1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0009615| response to virus CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1A1;CYP2C9;CRYZ GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 GO:0006691| leukotriene metabolic process ALOX5;ABCC1;ALOX15 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0099133| ABCC1 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0060326| cell chemotaxis ABCC1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0009308| amine metabolic process CYP1A1 GO:0007568| aging CYP1A1;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD;CAT GO:0006810| transport ABCB11;TRPV2;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0009611| response to wounding GPX1;CYP1A1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;SLC22A6 GO:0010041| response to iron(III) ion CYP1A1 GO:0055085| transmembrane transport CACNA1H;TRPV3;ABCB11;TRPV2;CACNA1G;SLC22A6;ABCC1;TRPA1;VDAC1;TRPV4;CACNA1I;TRPV1;ABCG2;TRPM8 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0002933| CYP1A1;CYP3A5;CYP3A7;CYP3A4 GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;SOD1 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0001666| response to hypoxia CYP1A1;CHRNA7;CAT GO:0035725| sodium ion transmembrane transport ABCB11;CACNA1H;CACNA1G;CACNA1I GO:0070988| demethylation CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0009692| ethylene metabolic process CYP1A1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0032502| developmental process CYP1A1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:1900087| CYP1A1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:0099039| ABCC1 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0043010| camera-type eye development CYP1A1 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0009624| response to nematode CYP1A1 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0098656| VDAC1;SLC22A6 GO:0070365| hepatocyte differentiation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 20835:[DB14011 DB05188] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05188|KD3010 PPARD common genes common pathways GO:0014823| response to activity PPARD;CAT GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARD;PPARG GO:0001890| placenta development PPARG;SOD1;PPARD GO:0060612| adipose tissue development PPARD;ACAT1 GO:0019395| fatty acid oxidation PPARD;PPARG GO:0008283| cell proliferation CYP1A1;PPARD;HTR1A;GPX1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARD;PPARG GO:0007566| embryo implantation SOD1;PTGS2;PPARD GO:0007507| heart development PPARD;PPARG GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;PPARD;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0006351| transcription, DNA-dependent PPARD;PPARG GO:0045598| regulation of fat cell differentiation PPARD;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARD;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARD;PPARG GO:0015758| glucose transport PLA2G1B;PPARD GO:0045892| negative regulation of transcription, DNA-dependent PPARG;PPARD GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;PPARD;SOD1 GO:0010628| positive regulation of gene expression TRPV4;PPARD GO:0006915| apoptotic process GPX1;PPARD;VDAC1 GO:0032966| negative regulation of collagen biosynthetic process PPARD;PPARG GO:0071456| cellular response to hypoxia PTGS2;OPRD1;PPARD;SLC29A1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PPARD;CAT GO:0046697| decidualization PPARD;PTGS2 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PPARD GO:0009062| fatty acid catabolic process PPARD;FAAH GO:0033189| response to vitamin A PPARD;CAT;CYP1A1;PPARG GO:0050728| negative regulation of inflammatory response PPARD;CNR2 GO:0006355| regulation of transcription, DNA-dependent PPARG;PPARD GO:0045893| positive regulation of transcription, DNA-dependent PPARD;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;PPARD GO:0008284| positive regulation of cell proliferation HMGCR;PPARD;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;PPARD;HMGCR GO:0006635| fatty acid beta-oxidation PPARD;ACAT1 GO:0008203| cholesterol metabolic process CAT;HMGCR;PPARD GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PPARD GO:0042060| wound healing ALOX15;OPRM1;PPARD GO:0030308| negative regulation of cell growth PPARG;PPARD 20836:[DB14011 DB05767] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1;TNF GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;CYP1A2;OPRM1;NFKB2;CYP1A1;IL1B;IDO1 GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0046330| positive regulation of JNK cascade TNF;TRPV4;IL1B GO:0071639| positive regulation of monocyte chemotactic protein-1 production TRPV4;IL1B GO:0001660| fever generation TRPV1;IL1B GO:0009615| response to virus CYP1A1;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNF;NFKB2;IL1B;PLA2G1B;IL6;NFKB1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;IL6;IL1B GO:0043066| negative regulation of apoptotic process GPX1;CAT;NFKB1;PTGS2;HMGCR;SOD1;IL6 GO:0034097| response to cytokine stimulus NFKB2;PTGS2;AANAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter NFKB1;PPARG;NFKB2;TNF;TRPV4;TRPV1 GO:0045087| innate immune response PPARG;NFKB2;NFKB1 GO:0043312| neutrophil degranulation NFKB1;CAT;ALOX5 GO:0050830| defense response to Gram-positive bacterium IL6;PLA2G1B;TNF GO:0030593| neutrophil chemotaxis IL1B;PLA2G1B GO:0006355| regulation of transcription, DNA-dependent NFKB2;PPARG;NFKB1 GO:0071407| cellular response to organic cyclic compound IL1B;CYP1B1;TNF;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;TNF;IL6;IL1B;NFKB1 GO:0046427| positive regulation of JAK-STAT cascade IL6;CYP1B1 GO:0050728| negative regulation of inflammatory response NFKB1;CNR2 GO:0048661| positive regulation of smooth muscle cell proliferation IL6;TNF;PTGS2;HMGCR GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0002446| neutrophil mediated immunity IL6;PLA2G1B GO:0007568| aging HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;NFKB2;CYP1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;IL1B;TNF GO:0032966| negative regulation of collagen biosynthetic process IL6;PPARG GO:0070374| positive regulation of ERK1 and ERK2 cascade TNF;ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0006915| apoptotic process NFKB1;GPX1;IL1B;VDAC1 GO:0000187| activation of MAPK activity IL1B;PLA2G1B;TNF;CHRNA7;SOD1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;IL1B GO:0010628| positive regulation of gene expression IL1B;IL6;TRPV4;TNF GO:0043406| positive regulation of MAP kinase activity TNF;HTR2A GO:0071356| cellular response to tumor necrosis factor NFKB1;TRPV1 GO:0048511| rhythmic process AANAT;NFKB2;PPARG GO:0043407| negative regulation of MAP kinase activity IL1B;SMPD1;HMGCR GO:0010033| response to organic substance TNF;TRPA1;PPARG;CYP1A1;SOD1;CYP1A2;PTGS2 GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG;NFKB1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;NFKB1 GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;IL1B;PTGS2 GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0031622| positive regulation of fever generation TNF;IL1B;PTGS2;CNR1 GO:0006351| transcription, DNA-dependent PPARG;NFKB2;NFKB1 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;TNF;PPARG;IL6;TRPV1;CYP1B1;IDO1 GO:0071260| cellular response to mechanical stimulus NFKB1;PTGS2;IL1B GO:0010629| negative regulation of gene expression OPRD1;NFKB1;TNF GO:0001934| positive regulation of protein phosphorylation TNF;IL1B;CHRNA7 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;CAT;TNF;NFKB2;IL1B;IL6;PLA2G1B GO:0006954| inflammatory response IL6;TRPV1;IDO1;IL1B;ALOX15;TNF;NFKB2;PTGS1;ALOX5;NFKB1;PTGS2;CNR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;IL6;PPARG;TNF GO:0006955| immune response CNR2;OPRD1;TNF;IL1B;IL6 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;IL6 GO:2000778| positive regulation of interleukin-6 secretion TRPV4;IL1B GO:0051384| response to glucocorticoid stimulus PTGS2;TNF;IL6 GO:0007566| embryo implantation PTGS2;SOD1;IL1B GO:0050796| regulation of insulin secretion CNR1;IL1B;TNF GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0034116| positive regulation of heterotypic cell-cell adhesion IL1B;ALOX15;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;TNF;IL6 GO:0007165| signal transduction OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;CHRNA7;NFKB1;SMPD1;GPR18;NFKB2;PPARG;PLA2G1B;CACNA1I;IL1B GO:0006919| activation of caspase activity PPARG;TNF GO:0051781| positive regulation of cell division IL1B;CAT GO:0070301| cellular response to hydrogen peroxide CYP1B1;IL6 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;IL1B;IL6;CYP1B1 20837:[DB14011 DB06820] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes CYP2C9;CYP1A2;CYP2D6 common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2;AANAT;ACAT1;PPARG;CYP1A1;TRPA1 GO:0019627| urea metabolic process CYP2C9 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0009791| post-embryonic development CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0051100| negative regulation of binding CYP2D6 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0043603| cellular amide metabolic process CYP2C9 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP2C9;CYP1A1 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0010468| regulation of gene expression CYP1A2 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A4;CYP2D6;CYP3A5 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CYP1A1;PPARG;TRPA1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0042737| drug catabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0019369| arachidonic acid metabolic process ALOX15;CYP2D6;DAGLA;CYP1B1;FAAH GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 20838:[DB14011 DB04268] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04268|Methylumbelliferyl Chitotriose LYZ common genes common pathways GO:0043312| neutrophil degranulation LYZ;ALOX5;CAT GO:0050830| defense response to Gram-positive bacterium LYZ;PLA2G1B GO:0008152| metabolic process ACAT1;LYZ;SMPD1 GO:0006954| inflammatory response TRPV1;LYZ;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0001895| retina homeostasis LYZ;SOD1 20839:[DB14011 DB03504] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03504|9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0009409| response to cold TRPM8;HSP90AA1;PPARG;TRPA1 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;HSP90AA1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;HSP90AA1;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;OPRM1;PTGS2 20840:[DB14011 DB00500] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes PTGS1;PTGS2 common pathways GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:1902219| PTGS2 GO:0006569| tryptophan catabolic process IDO1;TDO2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0097756| HMGCR;PTGS2 GO:0007568| aging CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;MPO;CAT GO:0030282| bone mineralization ALOX15;PTGS2 GO:0046697| decidualization PTGS2 GO:0051260| protein homooligomerization ACAT1;GLRA3;SLC22A6;GLRA1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;MPO;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;ALB;GSR GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;SLC22A6;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0042744| hydrogen peroxide catabolic process MPO;GPX1;CAT GO:0019441| tryptophan catabolic process to kynurenine IDO1;TDO2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MPO;CNR1;OPRM1;CYP1A2;CNR2;PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0071284| cellular response to lead ion PTGS2 GO:0002576| platelet degranulation ALB;SOD1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0009612| response to mechanical stimulus TRPV4;PPARG;MPO GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;MPO;CAT;ALB GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0043312| neutrophil degranulation CAT;MPO;ALOX5 GO:0042493| response to drug HTR2A;SOD1;CYP1A2;PTGS2;CAT;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;ABCG2 GO:0032094| response to food OPRM1;MPO;CYP1A1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP1A1;CYP2C9;MPO;GPX1;ALOX5;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;TDO2;SOD1;CYP3A4 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX15;PTGS2;ALOX5;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0009750| response to fructose stimulus PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2;PLA2G1B GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0001895| retina homeostasis ALB;SOD1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0098656| SLC22A6;VDAC1 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain TRPA1;TRPV1;HTR2A;CNR1;OPRM1;CNR2;PTGS2;OPRD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:1990776| PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;CYP1A2;PTGS2;HMGCR;ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;PPARG;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPV1;TRPM8;TDO2;CAT GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS2;CNR2;ALOX5;PTGS1 GO:0019430| removal of superoxide radicals SOD1;MPO GO:0071498| cellular response to fluid shear stress PTGS2 20841:[DB14011 DB00069] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00069|Interferon alfacon-1 IFNAR1;IFNAR2 common genes common pathways GO:0009615| response to virus CYP1A1;IFNAR2;IFNAR1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;PTGS2;CNR2;OPRM1;IFNAR1;CYP1A2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNAR2 20842:[DB14011 DB13869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR2;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;PPARG;ESR2;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PLA2G1B;ESR2;PPARG GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;ESR1;TRPV1 GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006351| transcription, DNA-dependent ESR1;ESR2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0007165| signal transduction CACNA1I;PLA2G1B;ESR2;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;ESR1;HTR1A;GPR55 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;ESR1;HTR2A;OPRM1 20843:[DB14011 DB08143] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08143|5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 20844:[DB14011 DB02820] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways GO:0006629| lipid metabolic process PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;HSD17B10;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9 GO:0051289| protein homotetramerization HSD17B10;CAT;TRPA1;CRYZ;TRPM8;TRPV1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP3A4;HSD17B10;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0009083| branched chain family amino acid catabolic process ACAT1;HSD17B10 20845:[DB14011 DB02155] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02155|Balanol Analog 8 PRKACA common genes common pathways GO:0071333| cellular response to glucose stimulus PRKACA;SLC29A1 GO:0034605| cellular response to heat TRPV4;TRPV1;PRKACA;PTGS2 GO:0002027| regulation of heart rate PRKACA;CACNA1G GO:0061136| regulation of proteasomal protein catabolic process PRKACA;GPX1 20846:[DB14011 DB09498] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09498|Strontium chloride Sr-89 ALPPL2;ALPL;SLC8A1;CACNA1I common genes CACNA1I common pathways GO:0051481| reduction of cytosolic calcium ion concentration SLC8A1;OPRM1 GO:0070509| calcium ion import CACNA1H;SLC8A1;CACNA1G;CACNA1I;TRPV4 GO:0030317| sperm motility CACNA1I GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;ALPL;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0035902| response to immobilization stress SLC8A1;CYP1A2;CYP1A1;PPARG GO:0046677| response to antibiotic ALPL;CYP1A1;SOD1 GO:0071407| cellular response to organic cyclic compound ALPL;CYP1B1;CYP1A1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT;SLC8A1 GO:0006810| transport TRPV2;ABCG2;CACNA1I;TRPV1;ABCC1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC8A1;SLC29A1 GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;CHRNA7;SLC8A1;HTR2A;GPR12 GO:0006936| muscle contraction GLRA1;CACNA1H;SLC8A1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;SLC8A1;TRPV2 GO:0001666| response to hypoxia CYP1A1;CAT;CHRNA7;SLC8A1 GO:0035725| sodium ion transmembrane transport SLC8A1;CACNA1H;CACNA1I;CACNA1G GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;CACNA1H GO:0030431| sleep CACNA1I;SLC29A1;HTR2A GO:0060078| regulation of postsynaptic membrane potential CHRNA7;SLC8A1 GO:0002027| regulation of heart rate SLC8A1;CACNA1G GO:0008152| metabolic process SMPD1;ALPPL2;ALPL;ACAT1 GO:0042542| response to hydrogen peroxide CAT;GPX1;SLC8A1;SOD1;TRPA1 GO:0071320| cellular response to cAMP AANAT;SLC8A1 GO:0086010| CACNA1I;CACNA1G;CACNA1H GO:0051924| regulation of calcium ion transport OPRD1;SLC8A1 GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;TRPV2;SLC8A1;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4 GO:0001649| osteoblast differentiation CAT;ALPL GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;SLC8A1;OPRM1;HTR2A GO:0051384| response to glucocorticoid stimulus ALPL;PTGS2 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1I;CACNA1G;CACNA1H GO:0007165| signal transduction HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0034765| regulation of ion transmembrane transport CACNA1G;CACNA1I;CACNA1H GO:0070588| calcium ion transmembrane transport SLC8A1;TRPV2;CHRNA7;TRPV3;OPRM1;CACNA1H;CACNA1I;TRPV4;TRPV1;TRPM8;CACNA1G;TRPA1 GO:0033280| response to vitamin D ALPL;PTGS2 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;SLC8A1 GO:0007584| response to nutrient SLC8A1;CNR1;HMGCR;PPARG 20847:[DB14011 DB00223] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00223|Diflorasone NR3C1 common genes common pathways GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;NR3C1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0006351| transcription, DNA-dependent PPARG;NR3C1 GO:0006915| apoptotic process GPX1;NR3C1;VDAC1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR3C1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;NR3C1 20848:[DB14011 DB02432] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02432|RU90395 SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0009615| response to virus SRC;CYP1A1 GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;SRC;GPX1;CAT GO:0045087| innate immune response SRC;PPARG GO:0007155| cell adhesion CYP1B1;SRC GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;SRC;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0002376| immune system process IDO1;SRC GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0042542| response to hydrogen peroxide SOD1;CAT;GPX1;SRC;TRPA1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2;SRC GO:0035556| intracellular signal transduction SRC;PLA2G1B GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0008283| cell proliferation CYP1A1;HTR1A;SRC;GPX1 GO:0045453| bone resorption GPR55;SRC GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;SRC GO:0070542| response to fatty acid CAT;SRC;PTGS2 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;SRC 20849:[DB14011 DB02481] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02481|N-Benzylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1;CYP2C9;CYP1A1;CRYZ;ADH1B;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1 20850:[DB14011 DB00106] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00106|Abarelix GNRHR common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;GNRHR;CACNA1I;PLA2G1B;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GNRHR;GPR18;PPARG 20851:[DB14011 DB06947] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06947|1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide F2 common genes common pathways GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;F2 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1;GPR18;PPARG;F2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression CYP1A2;F2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;F2 20852:[DB14011 DB00014] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00014|Goserelin LHCGR;GNRHR common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;LHCGR;HTR2A GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;LHCGR;OPRD1;OPRM1;CNR2 GO:0007186| G-protein coupled receptor signaling pathway LHCGR;HTR1A;GPR55;CNR1;GPR12;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18;GNRHR GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;LHCGR;OPRD1;OPRM1;CNR2;GNRHR;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0050890| cognition LHCGR;CHRNA7 20853:[DB14011 DB14062] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14062|Concanamycin A ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006810| transport TRPV2;ABCG2;CACNA1I;ABCB1;TRPV1;ABCC1 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPV1;ABCB1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1 GO:0042493| response to drug ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1;CAT;SOD1;HTR2A;CYP1A2;PTGS2 20854:[DB14011 DB03596] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03596|N-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide CA2 common genes common pathways GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;PPARG;CYP1A1;TRPA1;CA2 20855:[DB14011 DB14514] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14514|Magnesium levulinate ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure PTGS1;PTGS2;ATP1A1;SOD1;PPARG GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;ATP1A1;GLRA3;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0034220| ion transmembrane transport ATP1A1;GLRA3;CHRNA7;TRPA1;GLRA1;TRPV1;GLRB GO:0086002| ATP1A1;CACNA1G GO:0042493| response to drug CAT;CYP1A2;PTGS2;HTR2A;SOD1;ATP1A1;ABCG2;SMPD1;ABCC1;TRPA1;PPARG;CYP1A1 20856:[DB14011 DB04278] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;IL2;OPRM1;HTR2A GO:0050729| positive regulation of inflammatory response IL2;TRPV4 GO:0065009| regulation of molecular function IL2;TRPV1 GO:0045471| response to ethanol IL2;SOD1;CNR1;HMGCR;OPRM1;CAT GO:0001934| positive regulation of protein phosphorylation IL2;CHRNA7 GO:0006955| immune response OPRD1;CNR2;IL2 GO:0030217| T cell differentiation IL2;GPR18 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;IL2;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0002376| immune system process IL2;IDO1 GO:0007155| cell adhesion IL2;CYP1B1 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IL2;PPARG GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;IL2 GO:0050728| negative regulation of inflammatory response CNR2;IL2 20857:[DB14011 DB04787] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04787|Tanaproget PGR common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;PGR GO:0043401| steroid hormone mediated signaling pathway PPARG;PGR GO:0010629| negative regulation of gene expression OPRD1;PGR GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;OPRM1;CNR2;PLA2G1B;PGR;CACNA1I;GPR18;PPARG;SMPD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;PLA2G1B;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;PGR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;PGR 20858:[DB14011 DB07001] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07001|(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine NOS3 common genes common pathways GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;NOS3 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;IDO1;GSR;CYP2C19;NOS3;CYP2D6;CYP3A5;ALOX15;CYP17A1 GO:0042311| vasodilation GPX1;NOS3 GO:0030324| lung development NOS3;CYP1A2 GO:0043542| endothelial cell migration CYP1B1;NOS3 GO:1902042| NOS3;GPX1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;NOS3;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PPARG;NOS3;SOD1;PTGS2;PTGS1 GO:0043267| negative regulation of potassium ion transport HTR2A;NOS3 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3 GO:0045454| cell redox homeostasis GSR;NOS3;GPX1 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;NOS3 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0045776| negative regulation of blood pressure NOS3;CNR1 GO:0001525| angiogenesis PTGS2;CYP1B1;NOS3 20859:[DB14011 DB01116] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0034220| ion transmembrane transport TRPA1;GLRA1;CHRNA10;TRPV1;GLRB;GLRA3;CHRNA7 GO:0042493| response to drug BCHE;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;CAT GO:0007612| learning BCHE;VDAC1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CHRNA10 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;CHRNA10;GLRB;TRPV1 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;CHRNA10;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0008285| negative regulation of cell proliferation CYP1B1;BCHE;PPARG;OPRM1;PTGS2 GO:0007584| response to nutrient HMGCR;CNR1;BCHE;PPARG GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;CHRNA10 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;TRPV3;OPRM1;CACNA1H;TRPM8;CHRNA10;CACNA1I;TRPV4;TRPV1;TRPA1;CACNA1G GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;CHRNA10 GO:0006816| calcium ion transport TRPM8;CACNA1I;TRPV4;TRPV1;CHRNA10;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;TRPV3 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;CHRNA10 20860:[DB14011 DB09086] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09086|Eugenol ESR1;ESR2;AR;TRPV3 common genes TRPV3 common pathways GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0009408| response to heat TRPV1;TRPV2;SOD1;TRPV3 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0006816| calcium ion transport TRPM8;TRPV4;CACNA1I;TRPV1;TRPA1;CACNA1G;CHRNA7;TRPV2;CACNA1H;TRPV3 GO:0006351| transcription, DNA-dependent ESR1;AR;PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;PPARG;ESR2 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPM8;CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7 GO:0090280| positive regulation of calcium ion import TRPV3;TRPV2 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;AR;PPARG;CYP1B1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV1;TRPV4 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;ESR1;OPRD1;OPRM1;CNR2;CHRNA7;AR;GPR18;PPARG;SMPD1;ESR2;PLA2G1B;CACNA1I GO:0070588| calcium ion transmembrane transport CACNA1G;TRPA1;CACNA1I;TRPV4;TRPV1;TRPM8;TRPV3;OPRM1;CACNA1H;TRPV2;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;ESR2;PPARG GO:0042636| negative regulation of hair cycle TRPV3 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG;AR;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;AR;PPARG;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;TRPV1;TRPV4;PPARG;AR;ESR1 GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;ESR2;PLA2G1B GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV1;VDAC1;CACNA1I;TRPV4;TRPA1;ABCC1;CACNA1G GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport TRPV2;AR;TRPV1;CACNA1I;ABCG2;ABCC1 GO:0032355| response to estradiol stimulus ESR1;CYP1A2;PTGS2;CAT GO:0009266| response to temperature stimulus TRPM8;TRPV2;TRPV3 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1 20861:[DB14011 DB07675] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes PPARG common pathways GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process IDO1;CYP1B1;TRPV1;PPARG;SMPD1;SOD1;CNR1;PTGS2 GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0006919| activation of caspase activity PPARG GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0007165| signal transduction SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0030224| monocyte differentiation PPARG GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0030308| negative regulation of cell growth PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation PPARG;VDAC1 GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis PPARG;TRPV4;CNR1 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A;GPR18;PPARG 20862:[DB14011 DB05038] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05038|Anatibant BDKRB2 common genes common pathways GO:1902219| PTGS2;BDKRB2 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;BDKRB2;GPR55;HTR1A;HTR2A;CNR1;GPR12 GO:0042311| vasodilation BDKRB2;GPX1 GO:0050482| arachidonic acid secretion PLA2G1B;BDKRB2 GO:0006939| smooth muscle contraction BDKRB2;HTR2A GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;HTR2A;CNR1;GPR12;GPR55;HTR1A;BDKRB2;OPRD1;CNR2;OPRM1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;OPRM1;BDKRB2;HTR2A GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;BDKRB2;CNR2;PTGS2;PTGS1;ALOX5 GO:0042310| vasoconstriction BDKRB2;HTR1A GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;BDKRB2 20863:[DB14011 DB07250] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07250|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5- TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0007155| cell adhesion CYP1B1;EPHB4 GO:0001525| angiogenesis PTGS2;EPHB4;CYP1B1 20864:[DB14011 DB06213] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06213|Regadenoson ADORA2A common genes common pathways GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;ADORA2A;SMPD1 GO:0001975| response to amphetamine ADORA2A;SOD1;CNR2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;ADORA2A;PPARG;CYP1B1 GO:0051881| regulation of mitochondrial membrane potential SOD1;OPRD1;ADORA2A GO:0042755| eating behavior OPRM1;OPRD1;ADORA2A GO:0007188| G-protein signaling, coupled to cAMP nucleotide second messenger ADORA2A;CNR1 GO:0051924| regulation of calcium ion transport OPRD1;ADORA2A GO:0007600| sensory perception OPRM1;TRPV2;ADORA2A GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;TRPV1;IDO1;ALOX15;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2;GPX1 GO:0043524| negative regulation of neuron apoptosis ADORA2A;SOD1 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;ADORA2A;GPR18;PPARG GO:0060080| regulation of inhibitory postsynaptic membrane potential ADORA2A;GLRA1 GO:0031000| response to caffeine PPARG;ADORA2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0050714| positive regulation of protein secretion PLA2G1B;ADORA2A GO:0006915| apoptotic process VDAC1;ADORA2A;GPX1 GO:0007626| locomotory behavior ADORA2A;SOD1;OPRM1 GO:0042311| vasodilation GPX1;ADORA2A GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;ADORA2A;CHRNA7;SLC29A1;GLRA3;OPRM1 GO:0050728| negative regulation of inflammatory response ADORA2A;CNR2 GO:0006355| regulation of transcription, DNA-dependent PPARG;ADORA2A GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;ADORA2A;TRPA1;ABCC1;SMPD1;ABCG2 20865:[DB14011 DB09327] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes SLC29A1 common pathways GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS GO:0006139| nucleobase-containing compound metabolic process SLC28A1;SLC29A2;SLC28A2;SLC29A1 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;SLC22A7;CACNA1G;TRPA1;GLRA1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8 GO:0008283| cell proliferation GPX1;SLC29A2;HTR1A;CYP1A1 GO:0009636| response to toxin TYMS;CYP1A1;CYP1B1;GPX1;CAT GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;TRPA1;TYMS;CYP1A1;PPARG GO:0098656| VDAC1;SLC22A7 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0042738| exogenous drug catabolic process CYP1A2;CYP2A6;CYP3A4;CYP2C19;CYP2C9 GO:0007595| lactation SLC29A1 GO:0015858| nucleoside transport SLC29A2;SLC29A1;SLC28A1 GO:0045471| response to ethanol SOD1;CNR1;OPRM1;HMGCR;CAT;TYMS GO:0030431| sleep SLC29A1;HTR2A;CACNA1I GO:0015862| uridine transport SLC29A1 GO:0055085| transmembrane transport TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;TRPA1;ABCC1;CACNA1G;SLC22A7;TRPV2;TRPV3;CACNA1H GO:1901642| SLC29A2;SLC28A3;SLC29A1;SLC28A2;SLC28A1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0007568| aging CAT;NAPEPLD;HTR2A;SOD1;CNR1;PTGS2;HMGCR;TYMS;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2C19;GSR;IDO1;CYP2D6;CYP17A1;ALOX15;CYP3A5;HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP2A6;CYP3A4;DPYD;PTGS1;ALOX5;GPX1;CAT GO:0042493| response to drug PPARG;CYP1A1;TYMS;TRPA1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0033189| response to vitamin A PPARG;TYMS;CYP1A1;CAT GO:0009804| coumarin metabolic process CYP1A1;CYP2D6;CYP2A6 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA3;OPRM1;CHRNA7;SLC29A1;GLRA1;TRPV1;GLRB GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0007623| circadian rhythm TYMS;AANAT GO:0034097| response to cytokine stimulus TYMS;AANAT;PTGS2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2A6;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0032259| methylation CYP1A2;TYMS 20866:[DB14011 DB08386] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0008152| metabolic process PDE10A;ACAT1;SMPD1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PDE10A;CHRNA7 GO:0007186| G-protein coupled receptor signaling pathway PDE10A;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1;PPARG;GPR18 20867:[DB14011 DB09374] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09374|Indocyanine green acid form IDH1;GLS;ABCC2;ABCB11 common genes common pathways GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2;ABCC2;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0046685| response to arsenic-containing substance ABCC2;CYP1A1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;IDH1;CYP2C9;CYP1A1;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP3A7;PTGS2;CYP1A2 GO:0043312| neutrophil degranulation CAT;ALOX5;IDH1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;CYP1A1;IDO1;ABCC2 GO:0071356| cellular response to tumor necrosis factor ABCC2;TRPV1 GO:0055085| transmembrane transport TRPV2;ABCB11;TRPV3;CACNA1H;ABCC2;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;ABCC1;CACNA1G GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLS;GLRA1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;IDH1;ABCC2 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCC2;ABCG2;ABCB11;TRPV2 GO:0051289| protein homotetramerization GLS;CAT;CRYZ;TRPA1;TRPM8;TRPV1 GO:0009408| response to heat ABCC2;TRPV1;TRPV2;SOD1;TRPV3 GO:0014047| glutamate secretion GLS;TRPV1 GO:0007268| synaptic transmission VDAC1;GLRB;CACNA1G;GLRA1;OPRD1;OPRM1;HTR2A;GLRA3;GLS GO:0007565| female pregnancy ABCC2;IDO1 GO:0035725| sodium ion transmembrane transport CACNA1H;ABCB11;CACNA1G;CACNA1I GO:0006749| glutathione metabolic process SOD1;GPX1;IDH1;GSR GO:0043627| response to estrogen stimulus ABCC2;PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;IDH1;TRPA1;PTGS2;CYP1A2;ACAT1;AANAT GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCC1 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 20868:[DB14011 DB04655] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04655|Metoprine HNMT common genes common pathways GO:0032259| methylation HNMT;CYP1A2 GO:0007420| brain development ACAT1;HNMT 20869:[DB14011 DB08744] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;NQO2;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5 GO:0022900| electron transport chain CYP1A2;NQO2;GSR;IDO1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;NQO2;CYP1A1;CYP2C9;CRYZ 20870:[DB14011 DB04253] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04253|Tretazicar NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2D6;CYP2C19;NQO2;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0022900| electron transport chain CYP1A2;NQO2;IDO1;GSR GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT;NQO2;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1 20871:[DB14011 DB06314] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06314|SGX-523 MET common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;MET GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;MET;OPRD1 GO:0008283| cell proliferation GPX1;HTR1A;MET;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG;PLA2G1B GO:0051897| positive regulation of protein kinase B signaling cascade MET;GPX1 20872:[DB14011 DB06246] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06246|Exisulind PDE4D;PDE4C;PDE5A;PDE2A;GSTP1;AKR1B1;AKR1B10 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B GO:0022900| electron transport chain IDO1;GSR;AKR1B1;CYP1A2 GO:0030224| monocyte differentiation PPARG;PDE2A GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP2C9;CYP1A1;AKR1B1;CRYZ;AKR1B10;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;AKR1B1;GSTP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PDE2A;PPARG;TRPV1;TRPV4 GO:0043312| neutrophil degranulation GSTP1;ALOX5;CAT GO:0000302| response to reactive oxygen species GSTP1;CAT;GPX1;SOD1 GO:0060135| maternal process involved in female pregnancy CNR1;AKR1B1 GO:0034599| cellular response to oxidative stress GSR;GSTP1;SOD1;CAT;GPX1 GO:0002674| negative regulation of acute inflammatory response GSTP1;PPARG GO:0043407| negative regulation of MAP kinase activity GSTP1;SMPD1;HMGCR GO:0043406| positive regulation of MAP kinase activity HTR2A;PDE5A GO:0042130| negative regulation of T cell proliferation IDO1;PDE5A GO:0010033| response to organic substance PPARG;CYP1A1;AKR1B1;TRPA1;SOD1;CYP1A2;PTGS2 GO:0043200| response to amino acid stimulus GLRA3;GLRB;GSTP1 GO:0031100| organ regeneration GSTP1;PPARG GO:0032720| negative regulation of tumor necrosis factor production CHRNA7;GPR18;GSTP1 GO:0098869| GSR;GSTP1;PTGS2;CAT;GPX1;PTGS1 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;PDE4D;OPRM1;CNR2;GPR18;PPARG;PDE2A;PDE4C GO:0032355| response to estradiol stimulus GSTP1;PTGS2;CYP1A2;CAT GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP2C9;CYP1A1;AKR1B10 GO:0007568| aging CYP1A1;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PDE4D;PTGS2;CAT GO:1904706| GSTP1;PPARG GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0031667| response to nutrient levels GSTP1;SOD1 GO:0006805| xenobiotic metabolic process CYP1B1;GSTP1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 GO:0008152| metabolic process SMPD1;PDE2A;PDE5A;GSTP1;ACAT1 GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0071260| cellular response to mechanical stimulus PDE2A;PTGS2 GO:0045471| response to ethanol GSTP1;CAT;SOD1;CNR1;HMGCR;OPRM1 GO:0006749| glutathione metabolic process SOD1;GPX1;GSR;GSTP1 GO:0001523| retinoid metabolic process AKR1B10;NAPEPLD GO:0032930| positive regulation of superoxide anion generation GSTP1;SOD1 GO:0009636| response to toxin CYP1A1;GSTP1;CYP1B1;CAT;GPX1 GO:0033591| response to L-ascorbic acid CAT;GSTP1 GO:0070588| calcium ion transmembrane transport CHRNA7;TRPV2;OPRM1;CACNA1H;TRPV3;TRPM8;TRPV1;TRPV4;CACNA1I;TRPA1;CACNA1G;PDE2A GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;PDE4D;OPRM1;CNR2;PDE4C;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;PDE2A;PDE5A GO:0050729| positive regulation of inflammatory response TRPV4;PDE2A GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;GSTP1 GO:0043117| positive regulation of vascular permeability TRPV4;PDE2A 20873:[DB14011 DB11811] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11811|Arhalofenate PPARG common genes PPARG common pathways GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0050872| white fat cell differentiation PPARG GO:0042752| regulation of circadian rhythm PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0048469| cell maturation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0045165| cell fate commitment PPARG GO:0007507| heart development PPARG GO:0042953| lipoprotein transport PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process ALOX15;CYP2D6;DAGLA;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0009409| response to cold TRPM8;TRPA1;PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0006919| activation of caspase activity PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043627| response to estrogen stimulus PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0055088| lipid homeostasis PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process CYP1A1;PPARG;HMGCR;CNR1 GO:0007165| signal transduction GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0030224| monocyte differentiation PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A CAT;CYP1A1;PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0032526| response to retinoic acid PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0030308| negative regulation of cell growth PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation PPARG;ACAT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0071300| cellular response to retinoic acid PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0010033| response to organic substance TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 GO:0002674| negative regulation of acute inflammatory response PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4 GO:0031100| organ regeneration PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0033993| response to lipid PPARG GO:0043388| positive regulation of DNA binding PPARG 20874:[DB14011 DB06096] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06096|NXN-188 NOS1;HTR1B;HTR1D common genes common pathways GO:0032229| negative regulation of synaptic transmission, GABAergic HTR1B;CNR2 GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A;HTR1B GO:0009636| response to toxin GPX1;CAT;HTR1D;CYP1B1;CYP1A1 GO:0043267| negative regulation of potassium ion transport NOS1;HTR2A GO:0006809| nitric oxide biosynthetic process NOS1;CYP1B1 GO:0033555| multicellular organismal response to stress IDO1;NOS1 GO:0045454| cell redox homeostasis NOS1;GSR;GPX1 GO:0007520| myoblast fusion CACNA1H;NOS1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway HTR1B;HTR1D;OPRD1;OPRM1 GO:0006939| smooth muscle contraction HTR1D;HTR2A GO:0007165| signal transduction PLA2G1B;HTR1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;HTR1D;OPRM1;CNR2 GO:0007610| behavior HTR1B;HTR2A;HTR1A GO:0007268| synaptic transmission GLRB;HTR1B;VDAC1;CACNA1G;GLRA1;OPRM1;OPRD1;HTR1D;HTR2A;GLRA3 GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C19;NOS1;CYP2C9 GO:0009408| response to heat TRPV1;NOS1;TRPV2;SOD1;TRPV3 GO:0045471| response to ethanol HTR1B;CAT;OPRM1;HMGCR;SOD1;CNR1 GO:0045776| negative regulation of blood pressure NOS1;CNR1 GO:0071312| cellular response to alkaloid HTR1B;TRPV1 GO:0042310| vasoconstriction HTR1B;HTR1D;HTR1A GO:0042136| neurotransmitter biosynthetic process DAGLA;NOS1 GO:0071502| cellular response to temperature stimulus HTR1B;TRPV1 GO:0042220| response to cocaine HTR1B;SMPD1;OPRM1;CNR1 GO:0001666| response to hypoxia CYP1A1;NOS1;CAT;CHRNA7 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HTR1D;OPRD1;CNR2;OPRM1;CNR1;HTR1B GO:0014059| regulation of dopamine secretion HTR1B;HTR2A GO:0007186| G-protein coupled receptor signaling pathway OPRD1;HTR1D;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;GPR18;PPARG;HTR1B GO:0071363| cellular response to growth factor stimulus NOS1;TRPV1;OPRD1;CAT GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;HTR1B;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NOS1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;NOS1;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR1B;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NOS1;PPARG GO:0042311| vasodilation GPX1;NOS1 GO:0050795| regulation of behavior HTR1D;HTR1A;HTR2A;HTR1B 20875:[DB14011 DB03227] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03227|Nicotinamide Mononucleotide NMNAT1;NMNAT3;BST1;ligA common genes common pathways GO:0043312| neutrophil degranulation BST1;ALOX5;CAT GO:0008284| positive regulation of cell proliferation BST1;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0009611| response to wounding NMNAT1;GPX1;NMNAT3;CYP1A1 GO:0050727| regulation of inflammatory response BST1;PTGS2 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;PLA2G1B;BST1;CACNA1I;SMPD1;PPARG;GPR18 20876:[DB14011 DB07461] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07461|3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE F2 common genes common pathways GO:0009611| response to wounding F2;CYP1A1;GPX1 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression F2;CYP1A2 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;F2 GO:0061844| F2;PLA2G1B GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 20877:[DB14011 DB05259] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05259|Glatiramer HLA-DRB1 common genes common pathways GO:0006955| immune response CNR2;OPRD1;HLA-DRB1 GO:0042130| negative regulation of T cell proliferation HLA-DRB1;IDO1 GO:0051262| protein tetramerization HMGCR;CAT;HLA-DRB1 GO:0002376| immune system process IDO1;HLA-DRB1 20878:[DB14011 DB07385] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07385|3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE NQO1 common genes common pathways GO:0006801| superoxide metabolic process SOD1;NQO1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;GPX1;ALOX5;PTGS1;NQO1;CYP1A1;CYP2C9;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1;NQO1 GO:0006979| response to oxidative stress PTGS2;SOD1;GPX1;PTGS1;CAT;NQO1 GO:0032355| response to estradiol stimulus NQO1;CYP1A2;PTGS2;CAT GO:0007568| aging CYP1A1;NQO1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:0019430| removal of superoxide radicals SOD1;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP3A4;PTGS1 GO:0045471| response to ethanol NQO1;HMGCR;OPRM1;CNR1;SOD1;CAT GO:0007584| response to nutrient PPARG;NQO1;CNR1;HMGCR GO:0070301| cellular response to hydrogen peroxide NQO1;CYP1B1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;TRPA1;NQO1;PPARG;CYP1A1 GO:0009636| response to toxin CYP1B1;CYP1A1;NQO1;CAT;GPX1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NQO1 20879:[DB14011 DB11254] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;TYR;CAT;ALOX5;PTGS1;GPX1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;TOP1;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TGM2;HMGCR GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;TGM2;OPRD1 GO:0007623| circadian rhythm TOP1;AANAT GO:0051591| response to cAMP AANAT;TYR GO:0048511| rhythmic process PPARG;AANAT;TOP1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;TGM2;GPR18 GO:0043277| apoptotic cell clearance ALOX15;TGM2 GO:0048538| thymus development SOD1;TYR GO:0051260| protein homooligomerization GLRA1;ACAT1;GLRA3;TGM2 GO:0016032| viral reproduction VDAC1;HTR2A;TOP1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;TGM2;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0008152| metabolic process SMPD1;ACAT1;TYR GO:0008283| cell proliferation GPX1;TYR;HTR1A;CYP1A1 GO:0033280| response to vitamin D PTGS2;TYR GO:0009411| response to UV TYR;CAT GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1;TYR GO:0050729| positive regulation of inflammatory response TRPV4;TGM2 20880:[DB14011 DB14700] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0055114| oxidation-reduction process HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;F8;CRYZ;CYP1A1;CYP2C9;CYP1B1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1 GO:0002576| platelet degranulation F8;SOD1 20881:[DB14011 DB01158] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;ATP1A1;PPARG GO:0006811| ion transport TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;ATP1A1;TRPV3;CACNA1H GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0086002| CACNA1G;ATP1A1 GO:0034220| ion transmembrane transport GLRA3;ATP1A1;CHRNA7;TRPA1;GLRA1;GLRB;TRPV1 GO:0042493| response to drug SOD1;HTR2A;ATP1A1;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 20882:[DB14011 DB02336] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02336|RU83876 SRC common genes common pathways GO:0008283| cell proliferation CYP1A1;SRC;GPX1;HTR1A GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;SRC GO:0070542| response to fatty acid PTGS2;CAT;SRC GO:0045453| bone resorption GPR55;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;GPX1;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0016032| viral reproduction HTR2A;SRC;VDAC1 GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1;SRC GO:0042542| response to hydrogen peroxide TRPA1;SOD1;SRC;GPX1;CAT GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0070374| positive regulation of ERK1 and ERK2 cascade SRC;CHRNA7;HMGCR;OPRM1;HTR2A;GPR55;TRPV4;ALOX15 GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SRC;SLC29A1 GO:0002376| immune system process SRC;IDO1 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;SRC;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;ABCG2 GO:0016236| macroautophagy VDAC1;SRC GO:0045893| positive regulation of transcription, DNA-dependent PPARG;SRC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0042127| regulation of cell proliferation PTGS2;PTGS1;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0009615| response to virus CYP1A1;SRC GO:0009612| response to mechanical stimulus TRPV4;PPARG;SRC GO:0043066| negative regulation of apoptotic process CAT;GPX1;SRC;SOD1;PTGS2;HMGCR 20883:[DB14011 DB06752] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06752|Chymopapain PRG2 common genes common pathways GO:0002376| immune system process PRG2;IDO1 GO:0043312| neutrophil degranulation CAT;PRG2;ALOX5 GO:0032693| negative regulation of interleukin-10 production IDO1;PRG2 GO:0006955| immune response PRG2;CNR2;OPRD1 20884:[DB14011 DB09095] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0042738| exogenous drug catabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0008209| androgen metabolic process CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ANXA3;PPARG GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP3A4;CYP1A2 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway NR3C1;PPARG GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;GPX1;NAAA;PTGS1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0051384| response to glucocorticoid stimulus PTGS2;ANXA3 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0007165| signal transduction GPR12;CNR1;HTR2A;GPR55;HTR1A;NR3C1;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0006355| regulation of transcription, DNA-dependent NR3C1;PPARG GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;GPX1;PTGS1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;NR3C1 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR3C1 GO:0070848| response to growth factor stimulus ANXA3;OPRM1 GO:0043312| neutrophil degranulation CAT;ALOX5;ANXA3 GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;NR3C1 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0045766| positive regulation of angiogenesis ANXA3;CYP1B1;CHRNA7 GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0036378| CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0031100| organ regeneration ANXA3;PPARG GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP1A1 20885:[DB14011 DB02386] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02386|Leucine Phosphonic Acid LAP3 common genes common pathways 20886:[DB14011 DB07903] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07903|3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE METAP1 common genes common pathways 20887:[DB14011 DB06558] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;EDNRB GO:0042311| vasodilation GPX1;EDNRB GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A;EDNRB GO:0000122| negative regulation of transcription from RNA polymerase II promoter EDNRB;TRPV4;TRPV1;PPARG GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;EDNRB;IDO1;CYP1A1 GO:0014824| artery smooth muscle contraction HTR2A;EDNRA GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;EDNRB GO:0048265| response to pain TRPV1;EDNRB;TRPA1 GO:0007186| G-protein coupled receptor signaling pathway EDNRA;PPARG;GPR18;EDNRB;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0007568| aging CYP1A1;EDNRB;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT GO:0001666| response to hypoxia CYP1A1;EDNRA;CHRNA7;CAT GO:0007202| activation of phospholipase C activity HTR2A;GPR55;EDNRA GO:0015758| glucose transport PLA2G1B;EDNRA GO:0042310| vasoconstriction HTR1A;EDNRA;EDNRB GO:0007399| nervous system development EDNRB;GLRB;SMPD1 GO:0007507| heart development EDNRA;PPARG GO:0007194| negative regulation of adenylate cyclase activity EDNRB;OPRM1 GO:0019233| sensory perception of pain OPRD1;OPRM1;CNR2;PTGS2;HTR2A;CNR1;TRPV1;EDNRB;TRPA1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;EDNRB;TRPV1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;EDNRB GO:0006939| smooth muscle contraction EDNRA;HTR2A GO:0007165| signal transduction SMPD1;PPARG;EDNRA;GPR18;PLA2G1B;CACNA1I;EDNRB;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CHRNA7 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway EDNRA;OPRD1;OPRM1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;EDNRA;TRPV4;TRPV1;EDNRB GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG;EDNRA;EDNRB GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;EDNRB;CYP1A1;PPARG;TRPA1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1;EDNRA GO:0051930| regulation of sensory perception of pain OPRD1;OPRM1;EDNRB 20888:[DB14011 DB13915] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CD19;TRPA1;TRPV1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;CD19 20889:[DB14011 DB06623] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06623|Flupirtine ADRA2A common genes common pathways GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;ADRA2A GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A GO:0042593| glucose homeostasis CNR1;PPARG;TRPV4;ADRA2A GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;GPR18;PPARG;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0030818| negative regulation of cAMP biosynthetic process ADRA2A;OPRM1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;ADRA2A GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus ADRA2A;CACNA1H GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A GO:0050796| regulation of insulin secretion CNR1;ADRA2A 20890:[DB14011 DB00428] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes CYP1A2;CYP1A1 common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;GPX1;ALOX5;PTGS1;CYP2E1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0032094| response to food CYP1A1;OPRM1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0042493| response to drug ABCG2;ABCB1;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;CAT;SOD1;HTR2A;CYP2E1;PTGS2;CYP1A2 GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0009308| amine metabolic process CYP1A1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2;TRPV1 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0009812| flavonoid metabolic process CYP1A1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;PTGS2;CYP1A2;OPRM1;CYP1A1;IDO1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2;CYP2E1 GO:0032259| methylation CYP1A2 GO:0009615| response to virus CYP1A1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0055085| transmembrane transport ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1;SLC2A2;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0071615| oxidative deethylation CYP1A2 GO:0002933| CYP3A7;CYP3A4;CYP1A1;CYP3A5 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1B1;CYP1A1 GO:0015758| glucose transport PLA2G1B;SLC2A2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;CYP1A2;PTGS2 GO:0010193| response to ozone CYP2E1;CAT GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0006810| transport ABCC1;ABCB1;CACNA1I;TRPV1;ABCG2;TRPV2 GO:0007568| aging CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0010468| regulation of gene expression CYP1A2 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2E1;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP2C9;CYP1A1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:0009611| response to wounding GPX1;CYP1A1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0010041| response to iron(III) ion CYP1A1 GO:0009635| response to herbicide CYP1A1 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0048565| digestive tract development CYP1A1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0070988| demethylation CYP1A1 GO:0001889| liver development CYP1A1;ACAT1 GO:0045471| response to ethanol CAT;OPRM1;HMGCR;CYP2E1;SOD1;CNR1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0009692| ethylene metabolic process CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0008152| metabolic process ACAT1;SMPD1;MGEA5 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0009624| response to nematode CYP1A1 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;PPARG;CYP1A1;TRPA1 GO:0008283| cell proliferation HTR1A;GPX1;CYP1A1 GO:0045333| cellular respiration CYP1A2 GO:0070365| hepatocyte differentiation CYP1A1 GO:0017143| insecticide metabolic process CYP1A1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0032502| developmental process CYP1A1 GO:0050796| regulation of insulin secretion SLC2A2;CNR1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0019216| regulation of lipid metabolic process PPARG;CYP1A1;CNR1;HMGCR GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:1900087| CYP1A1 GO:0006641| triglyceride metabolic process CAT;GPX1;CYP2E1 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP2C9;CYP1A1 GO:0043010| camera-type eye development CYP1A1 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 20891:[DB14011 DB05793] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05793|PRO-542 FFAR4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;FFAR4;GPR55;HTR1A;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;HTR2A;GPR55;HMGCR;FFAR4;OPRM1;ALOX15;TRPV4 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;FFAR4;HMGCR;CAT;GPX1 GO:0050728| negative regulation of inflammatory response FFAR4;CNR2 GO:0045444| fat cell differentiation GPX1;FFAR4 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;FFAR4;HTR1A;GPR55;HTR2A;GPR12;CNR1;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0032870| cellular response to hormone stimulus CACNA1H;FFAR4 20892:[DB14011 DB04081] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04081|(4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CA2;TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion AANAT;CA2 20893:[DB14011 DB03270] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03270|2,6-Difluorobenzenesulfonamide CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion AANAT;CA2 GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CA2;PPARG;CYP1A1;TRPA1 20894:[DB14011 DB05133] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05133|VP025 IL1B common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process IL1B;TRPV1;PTGS2;OPRM1 GO:0010628| positive regulation of gene expression IL1B;TRPV4 GO:0043407| negative regulation of MAP kinase activity HMGCR;IL1B;SMPD1 GO:0006915| apoptotic process GPX1;VDAC1;IL1B GO:0000187| activation of MAPK activity IL1B;PLA2G1B;SOD1;CHRNA7 GO:0045766| positive regulation of angiogenesis CYP1B1;IL1B;CHRNA7 GO:0008284| positive regulation of cell proliferation IL1B;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;IL1B;PPARG GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CYP1A2;OPRM1;CNR1;IL1B;IDO1;CYP1A1 GO:0046330| positive regulation of JNK cascade IL1B;TRPV4 GO:0071639| positive regulation of monocyte chemotactic protein-1 production IL1B;TRPV4 GO:0001660| fever generation TRPV1;IL1B GO:0071407| cellular response to organic cyclic compound IL1B;CYP1B1;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;PPARG GO:0030593| neutrophil chemotaxis PLA2G1B;IL1B GO:0034116| positive regulation of heterotypic cell-cell adhesion IL1B;ALOX15 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;CACNA1I;PLA2G1B;IL1B;SMPD1;GPR18;PPARG GO:0007566| embryo implantation SOD1;PTGS2;IL1B GO:0050796| regulation of insulin secretion CNR1;IL1B GO:0051781| positive regulation of cell division IL1B;CAT GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;IL1B;CYP1B1;PPARG GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;IL1B;CYP1B1 GO:0031622| positive regulation of fever generation PTGS2;CNR1;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;IL1B GO:0006955| immune response OPRD1;CNR2;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;IL1B;CAT GO:0006954| inflammatory response IDO1;IL1B;ALOX15;TRPV1;ALOX5;PTGS1;CNR2;PTGS2 GO:2000778| positive regulation of interleukin-6 secretion IL1B;TRPV4 GO:0001934| positive regulation of protein phosphorylation IL1B;CHRNA7 20895:[DB14011 DB03742] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03742|Compound 4-D ESR1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043401| steroid hormone mediated signaling pathway PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0007165| signal transduction GPR18;PPARG;SMPD1;CACNA1I;PLA2G1B;GPR12;CNR1;HTR2A;ESR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;ESR1;TRPV1;TRPV4 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR1 GO:0006355| regulation of transcription, DNA-dependent PPARG;ESR1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;PPARG;PLA2G1B GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRD1;OPRM1;HTR2A;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;PTGS2;OPRM1 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2;ESR1 20896:[DB14011 DB01278] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;CALCR;RAMP3 GO:0032355| response to estradiol stimulus RAMP2;CAT;CYP1A2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;RAMP1;PPARG;GPR18;RAMP3;CALCR;RAMP2 GO:0070374| positive regulation of ERK1 and ERK2 cascade RAMP3;CALCR;ALOX15;TRPV4;GPR55;HTR2A;OPRM1;HMGCR;CHRNA7 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1;RAMP2 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;RAMP3 GO:0001666| response to hypoxia RAMP2;CYP1A1;CAT;CHRNA7 GO:0010628| positive regulation of gene expression RAMP2;TRPV4;RAMP3;CALCR GO:0007202| activation of phospholipase C activity CALCR;HTR2A;GPR55 GO:0001525| angiogenesis CYP1B1;RAMP2;RAMP1;PTGS2 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CALCR;TRPV1 GO:0007507| heart development RAMP2;PPARG GO:0007565| female pregnancy IDO1;RAMP2 GO:0010942| positive regulation of cell death PTGS2;RAMP3;CALCR GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;RAMP1;TRPV2;TRPA1;CACNA1G;RAMP3;RAMP2;TRPM8;TRPV4;CACNA1I;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration CALCR;TRPV4;TRPV1;OPRM1;HTR2A GO:0051384| response to glucocorticoid stimulus PTGS2;CALCR GO:0033138| positive regulation of peptidyl-serine phosphorylation CALCR;RAMP3;OPRD1;PTGS2 GO:0007165| signal transduction HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;CALCR;PLA2G1B;CACNA1I GO:0032870| cellular response to hormone stimulus CACNA1H;RAMP2 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;RAMP2 20897:[DB14011 DB02721] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02721|4-Iodopyrazole ADH1C;ADH1B;ADH1A common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;ADH1A;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;ADH1A;ADH1B;CYP2C9;CYP1A1;CRYZ;GPX1;ALOX5;PTGS1;CAT;ADH1C;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1 20898:[DB14011 DB01269] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01269|Panitumumab EGFR common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;EGFR GO:0001503| ossification EGFR;ALOX15 GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;EGFR GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;EGFR GO:0051592| response to calcium ion EGFR;AANAT GO:0001889| liver development ACAT1;CYP1A1;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0045740| positive regulation of DNA replication EGFR;PLA2G1B GO:0008283| cell proliferation CYP1A1;EGFR;HTR1A;GPX1 GO:0014070| response to organic cyclic compound EGFR;TRPA1;CYP1A1;PPARG;ACAT1;AANAT;CYP1A2;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2;EGFR GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;EGFR;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0045907| positive regulation of vasoconstriction EGFR;HTR2A;PTGS2 GO:0046718| entry of virus into host cell HTR2A;EGFR GO:0050729| positive regulation of inflammatory response TRPV4;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2;HMGCR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0008284| positive regulation of cell proliferation EGFR;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;EGFR;PLA2G1B GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;EGFR GO:0030324| lung development CYP1A2;EGFR GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0042127| regulation of cell proliferation EGFR;PTGS2;PTGS1 GO:0042060| wound healing EGFR;ALOX15;OPRM1 GO:0007623| circadian rhythm AANAT;EGFR GO:0007611| learning or memory EGFR;CHRNA7;CNR1 GO:0043406| positive regulation of MAP kinase activity HTR2A;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0007202| activation of phospholipase C activity EGFR;HTR2A;GPR55 GO:0070374| positive regulation of ERK1 and ERK2 cascade HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;ALOX15;EGFR;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;EGFR;TRPV1 GO:0006979| response to oxidative stress EGFR;PTGS2;SOD1;GPX1;PTGS1;CAT GO:0033993| response to lipid PPARG;EGFR GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;EGFR GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;TRPV1;EGFR 20899:[DB14011 DB05053] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05053|MB-07803 FBP1 common genes common pathways GO:0051289| protein homotetramerization CRYZ;TRPA1;TRPM8;TRPV1;CAT;FBP1 GO:0008152| metabolic process SMPD1;ACAT1;FBP1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter FBP1;PPARG;TRPV1;TRPV4 GO:0030308| negative regulation of cell growth PPARG;FBP1 20900:[DB14011 DB01737] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01737|Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20901:[DB14011 DB09126] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;LHCGR;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR2;OPRM1;OPRD1;LHCGR;CNR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;LHCGR;OPRD1;OPRM1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;LHCGR;HTR1A;GPR55;CHRNA7 GO:0050890| cognition LHCGR;CHRNA7 20902:[DB14011 DB05369] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05369|HZT-501 HRH2 common genes common pathways GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger HRH2;CNR1;OPRD1;CNR2;OPRM1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;HRH2;HTR2A;GPR12;CNR1;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0045907| positive regulation of vasoconstriction HTR2A;HRH2;PTGS2 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HRH2;CNR1;GPR12;HTR2A;CHRNA7 GO:0007613| memory CHRNA7;PTGS2;HRH2;CNR1;HTR2A GO:0006955| immune response HRH2;CNR2;OPRD1 GO:0048565| digestive tract development HRH2;CYP1A1 GO:0008542| visual learning HRH2;HMGCR 20903:[DB14011 DB01348] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1;ACE GO:0006811| ion transport GLRA3;SLC15A2;TRPV3;CACNA1H;CHRNA7;TRPV2;GLRA1;TRPA1;SLC15A1;CACNA1G;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1 GO:0060047| heart contraction SOD1;GPX1;ACE GO:0050482| arachidonic acid secretion ACE;PLA2G1B GO:0007283| spermatogenesis ACE;SOD1;CNR1 GO:0055085| transmembrane transport TRPA1;SLC15A1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;SLC15A2;CACNA1H;TRPV3;TRPV2 GO:0002446| neutrophil mediated immunity PLA2G1B;ACE GO:0006810| transport ABCC1;SLC15A1;CACNA1I;TRPV1;ABCG2;SLC15A2;TRPV2 GO:0001822| kidney development ACE;CAT 20904:[DB14011 DB00961] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00961|Mepivacaine SCN10A common genes common pathways GO:0002027| regulation of heart rate CACNA1G;SCN10A GO:0019228| regulation of action potential in neuron CACNA1H;CACNA1G;SCN10A;CACNA1I GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SCN10A;CACNA1H GO:0019233| sensory perception of pain HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1;TRPV1;TRPA1;SCN10A GO:0086010| CACNA1H;CACNA1I;CACNA1G;SCN10A GO:0007600| sensory perception OPRM1;TRPV2;SCN10A GO:0034765| regulation of ion transmembrane transport SCN10A;CACNA1G;CACNA1I;CACNA1H GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN10A;CACNA1G GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;SCN10A;CACNA1G;GLRA1;TRPA1;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8 GO:0086016| CACNA1G;SCN10A GO:0055085| transmembrane transport ABCC1;CACNA1G;SCN10A;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;TRPM8;ABCG2;TRPV3;CACNA1H;TRPV2 20905:[DB14011 DB04703] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04703|Hesperidin AURKB common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;AURKB;PPARG GO:0007568| aging AURKB;CYP1A1;CAT;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2 GO:0008283| cell proliferation CYP1A1;AURKB;HTR1A;GPX1 GO:0034644| cellular response to UV PTGS2;AURKB 20906:[DB14011 DB06825] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06825|Triptorelin GNRHR common genes common pathways GO:0007165| signal transduction GNRHR;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0007186| G-protein coupled receptor signaling pathway GNRHR;GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55 20907:[DB14011 DB07216] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07216|(11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE FNTA;FNTB common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;FNTB;PTGS1 20908:[DB14011 DB01941] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways GO:0006355| regulation of transcription, DNA-dependent PPARG;RXRB GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RXRB;PLA2G1B GO:0006351| transcription, DNA-dependent RXRB;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;RXRB 20909:[DB14011 DB02096] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02096|FR221647 ADA common genes common pathways GO:0001666| response to hypoxia ADA;CHRNA7;CAT;CYP1A1 GO:0007568| aging CYP1A1;ADA;CAT;PTGS2;HMGCR;NAPEPLD;SOD1;HTR2A;CNR1 GO:0042493| response to drug ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ADA;CAT;CYP1A2;PTGS2;SOD1;HTR2A GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0043278| response to morphine ADA;OPRM1;CNR1 GO:0033197| response to vitamin E CAT;ADA GO:0030324| lung development CYP1A2;ADA GO:0043066| negative regulation of apoptotic process CAT;ADA;GPX1;SOD1;HMGCR;PTGS2 GO:0007155| cell adhesion ADA;CYP1B1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADA GO:0001890| placenta development ADA;SOD1;PPARG GO:0001889| liver development CYP1A1;ADA;ACAT1 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;GPX1;ADA;CAT 20910:[DB14011 DB01611] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01611|Hydroxychloroquine TLR7;TLR9;CYP2D6;ABCB1 common genes CYP2D6 common pathways GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0050729| positive regulation of inflammatory response TLR9;TRPV4;TLR7 GO:0007165| signal transduction PLA2G1B;CACNA1I;TLR9;SMPD1;PPARG;GPR18;TLR7;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0032088| negative regulation of NF-kappaB transcription factor activity TLR9;CYP1B1;CAT GO:0051100| negative regulation of binding CYP2D6 GO:0001774| microglial cell activation TRPV1;TLR7 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0071260| cellular response to mechanical stimulus TLR7;PTGS2 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9;NAAA;GPX1;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0006954| inflammatory response TLR7;TRPV1;TLR9;ALOX15;IDO1;CNR2;PTGS2;PTGS1;ALOX5 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;TLR9 GO:0006955| immune response OPRD1;CNR2;TLR7 GO:0006810| transport TRPV2;ABCB1;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0032735| positive regulation of interleukin-12 production TLR9;IDO1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP1A1;CYP2C9 GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C9;CYP2C19;CYP2D6 GO:0002376| immune system process TLR7;TLR9;IDO1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0010628| positive regulation of gene expression TLR9;TRPV4 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0046330| positive regulation of JNK cascade TRPV4;TLR9 GO:0045087| innate immune response TLR9;TLR7;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TLR9;PLA2G1B GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCB1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;CYP2D6;DAGLA;ALOX15 GO:0009804| coumarin metabolic process CYP1A1;CYP2D6 20911:[DB14011 DB01694] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01694|D-tartaric acid B3GAT1;TREM1;DDX6;HIF1AN;serA;lpxA;ATP6V1C1;phnA common genes common pathways GO:0055114| oxidation-reduction process HIF1AN;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT GO:0006355| regulation of transcription, DNA-dependent HIF1AN;PPARG GO:0045087| innate immune response TREM1;PPARG GO:0034220| ion transmembrane transport GLRA3;ATP6V1C1;CHRNA7;TRPA1;GLRA1;TRPV1;GLRB GO:0007283| spermatogenesis DDX6;CNR1;SOD1 GO:0006351| transcription, DNA-dependent HIF1AN;PPARG GO:0035556| intracellular signal transduction TREM1;PLA2G1B GO:0006811| ion transport CACNA1G;TRPA1;GLRA1;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;TRPM8;ATP6V1C1;TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7 20912:[DB14011 DB07514] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07514|3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one KDR common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0043066| negative regulation of apoptotic process KDR;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;ALOX15;TRPV4;KDR GO:0045766| positive regulation of angiogenesis CYP1B1;KDR;CHRNA7 GO:0001525| angiogenesis KDR;CYP1B1;PTGS2 GO:0016032| viral reproduction HTR2A;KDR;VDAC1 GO:0001934| positive regulation of protein phosphorylation KDR;CHRNA7 GO:0010629| negative regulation of gene expression KDR;OPRD1 20913:[DB14011 DB09270] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes HMGCR common pathways GO:0008542| visual learning HMGCR GO:0016032| viral reproduction VDAC1;LDLR;HTR2A GO:0045445| myoblast differentiation HMGCR GO:0010629| negative regulation of gene expression LDLR;OPRD1 GO:0006629| lipid metabolic process CYP2C9;PPARG;LDLR;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;NAPEPLD;CYP3A4;VLDLR;HMGCR;PTGS2;CYP1A2;GPX1;NAAA;PTGS1 GO:0007399| nervous system development SMPD1;GLRB;SDHA;VLDLR GO:0016126| sterol biosynthetic process HMGCR GO:0045471| response to ethanol CAT;CNR1;SOD1;OPRM1;HMGCR GO:0061045| negative regulation of wound healing HMGCR GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCG2 GO:0010664| negative regulation of striated muscle cell apoptosis HMGCR GO:0048643| positive regulation of skeletal muscle tissue development HMGCR GO:0007165| signal transduction GPR55;VLDLR;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1;VLDLR GO:0050729| positive regulation of inflammatory response LDLR;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0046718| entry of virus into host cell LDLR;HTR2A GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0006743| ubiquinone metabolic process HMGCR GO:0015936| coenzyme A metabolic process ACAT1;HMGCR GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;LDLR GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0006694| steroid biosynthetic process CYP17A1;HMGCR GO:0055114| oxidation-reduction process SOD1;SDHA;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP2C9;CYP1A1;GSR;IDO1;CYP2C19;CYP2D6;NDUFV3;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0022900| electron transport chain CYP1A2;SDHA;IDO1;GSR GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;ABCB1;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0010666| positive regulation of cardiac muscle cell apoptosis HMGCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;VLDLR GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0006695| cholesterol biosynthetic process HMGCR GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR GO:0008203| cholesterol metabolic process LDLR;VLDLR;HMGCR;CAT GO:0051262| protein tetramerization CAT;HMGCR GO:0043407| negative regulation of MAP kinase activity SMPD1;HMGCR GO:0010628| positive regulation of gene expression TRPV4;LDLR GO:0008299| isoprenoid biosynthetic process HMGCR GO:0045540| regulation of cholesterol biosynthetic process HMGCR GO:0055085| transmembrane transport TRPV1;ABCB1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;GPR55;HTR2A;OPRM1;HMGCR GO:0007568| aging CYP1A1;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CAT GO:0006810| transport ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1;TRPV2 GO:0097756| PTGS2;HMGCR GO:0008202| steroid metabolic process CYP2C9;CYP1A1;LDLR;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;VLDLR;CYP3A4;CYP1A2;CYP3A7;HMGCR 20914:[DB14011 DB13149] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13149|Protein S human F5;F10;PROC common genes common pathways GO:0001889| liver development ACAT1;PROC;CYP1A1 GO:0002576| platelet degranulation SOD1;F5 GO:0043066| negative regulation of apoptotic process CAT;GPX1;PROC;SOD1;PTGS2;HMGCR GO:0050728| negative regulation of inflammatory response CNR2;PROC GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 20915:[DB14011 DB12406] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12406|Lisofylline CYP1A2 common genes CYP1A2 common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP2C19 GO:0009403| toxin biosynthetic process CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP1A2 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP1A2;CYP3A7;PTGS1;CYP2C9;CYP3A5;CYP2C19;CYP2D6;CYP1B1 GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;NAAA;PTGS1;GPX1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0070989| oxidative demethylation CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0097267| CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0045333| cellular respiration CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0030324| lung development CYP1A2 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0032259| methylation CYP1A2 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0022900| electron transport chain CYP1A2;GSR;IDO1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1 GO:0032787| monocarboxylic acid metabolic process CYP2C9;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1 GO:0071615| oxidative deethylation CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;SOD1;PTGS2;CYP1A2 20916:[DB14011 DB07393] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes GSR common pathways GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19 GO:0034599| cellular response to oxidative stress GSR;SOD1;CAT;GPX1 GO:0098869| GSR;PTGS2;PTGS1;GPX1;CAT GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0006749| glutathione metabolic process SOD1;GPX1;GSR GO:0045454| cell redox homeostasis GSR;GPX1 20917:[DB14011 DB01839] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01839|Propylene glycol F13A1 common genes common pathways GO:0002576| platelet degranulation F13A1;SOD1 20918:[DB14011 DB05675] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05675|EP-2104R FGA common genes common pathways GO:1902042| GPX1;FGA GO:0045907| positive regulation of vasoconstriction FGA;PTGS2;HTR2A GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;SMPD1;FGA;PLA2G1B;CACNA1I GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;FGA GO:0051592| response to calcium ion AANAT;FGA GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;FGA;ALOX15;OPRM1;HMGCR;GPR55;HTR2A;CHRNA7 GO:0050714| positive regulation of protein secretion PLA2G1B;FGA GO:0002376| immune system process FGA;IDO1 GO:0002576| platelet degranulation SOD1;FGA GO:0045087| innate immune response PPARG;FGA 20919:[DB14011 DB02262] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0031000| response to caffeine DHODH;PPARG GO:0042493| response to drug ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT;DHODH GO:0055114| oxidation-reduction process CAT;DHODH;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP2C9;CYP1A1;CRYZ GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;DHODH;ACAT1;AANAT GO:0007565| female pregnancy IDO1;DHODH GO:0007595| lactation DHODH;SLC29A1 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;DHODH;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 20920:[DB14011 DB03035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03035|1,8-Di-Hydroxy-4-Nitro-Anthraquinone CSNK2A1 common genes common pathways GO:0007165| signal transduction OPRD1;CSNK2A1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;CSNK2A1 GO:0006915| apoptotic process CSNK2A1;GPX1;VDAC1 GO:0048511| rhythmic process PPARG;CSNK2A1;AANAT GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;CSNK2A1;HMGCR;PTGS2 GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG 20921:[DB14011 DB08084] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08084|IDD594 AKR1B1 common genes common pathways GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;AKR1B1;CYP1A2;PTGS2;SOD1 GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0043066| negative regulation of apoptotic process AKR1B1;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0022900| electron transport chain CYP1A2;IDO1;GSR;AKR1B1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1;AKR1B1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;AKR1B1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;AKR1B1 20922:[DB14011 DB03222] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03222|dATP POLB;recA;recA common genes common pathways GO:0006915| apoptotic process VDAC1;POLB;GPX1 GO:0007568| aging CYP1A1;POLB;CAT;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2 GO:0055093| response to hyperoxia CYP1A1;POLB;CAT GO:0010332| response to gamma radiation GPX1;POLB GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;PTGS2;CNR2;ALOX5;PTGS1;POLB GO:0045471| response to ethanol CNR1;SOD1;HMGCR;OPRM1;POLB;CAT 20923:[DB14011 DB04776] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways GO:0008283| cell proliferation GPX1;PDXK;HTR1A;CYP1A1 GO:0043312| neutrophil degranulation ALOX5;PDXK;CAT 20924:[DB14011 DB02494] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02494|Alpha-Hydroxy-Beta-Phenyl-Propionic Acid RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13;CPA1 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;RPL23;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;RPL23;PLA2G1B GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;RPL23 GO:0007283| spermatogenesis RPL10L;SOD1;CNR1 GO:0010628| positive regulation of gene expression TRPV4;RPL23;RPL11 GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT;RPL15 GO:0008283| cell proliferation HTR1A;RPL23A;GPX1;CYP1A1 20925:[DB14011 DB07379] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways GO:0010468| regulation of gene expression CYP1A2;CDK6 GO:0009615| response to virus CDK6;CYP1A1 GO:0045786| negative regulation of cell cycle PTGS2;CDK6 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CDK6 GO:0007165| signal transduction CACNA1I;PLA2G1B;CDK6;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;CDK6;CYP1B1 GO:0048146| positive regulation of fibroblast proliferation CDK6;PLA2G1B 20926:[DB14011 DB05255] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05255|Ronacaleret CASR;ADGRF1 common genes common pathways GO:0001503| ossification ALOX15;CASR GO:0051592| response to calcium ion AANAT;CASR GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;ADGRF1 GO:0006816| calcium ion transport TRPV2;CASR;CHRNA7;CACNA1H;TRPV3;TRPV1;TRPV4;CACNA1I;TRPM8;CACNA1G;TRPA1 GO:0051924| regulation of calcium ion transport OPRD1;CASR GO:0045907| positive regulation of vasoconstriction CASR;PTGS2;HTR2A GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CASR;CHRNA7;ADGRF1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;CASR GO:0007613| memory CHRNA7;ADGRF1;PTGS2;CNR1;HTR2A GO:0090280| positive regulation of calcium ion import TRPV2;CASR;TRPV3 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CASR;AANAT;ACAT1;PTGS2;CYP1A2 GO:0042311| vasodilation CASR;GPX1 GO:0008284| positive regulation of cell proliferation CHRNA7;CASR;HMGCR;PTGS2;HTR2A;HTR1A GO:0071333| cellular response to glucose stimulus CASR;SLC29A1 GO:0070509| calcium ion import TRPV4;CACNA1I;CACNA1G;CASR;CACNA1H GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CASR;HTR2A;OPRM1;OPRD1 GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG;CASR GO:0006874| cellular calcium ion homeostasis TRPV4;TRPM8;HTR2A;GPR12;CASR;CHRNA7 GO:0032793| positive regulation of CREB transcription factor activity OPRD1;ADGRF1 GO:0007186| G-protein coupled receptor signaling pathway CASR;ADGRF1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;PPARG;GPR18 GO:0007635| chemosensory behavior CASR;TRPV1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;CASR;SLC29A1 GO:0010628| positive regulation of gene expression TRPV4;CASR GO:0006915| apoptotic process GPX1;CASR;VDAC1 20927:[DB14011 DB08202] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08202|4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance CA2;PPARG;CYP1A1;TRPA1;SOD1;CYP1A2;PTGS2 20928:[DB14011 DB08601] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08601|tributylstannanyl NCOA2;RXRA common genes common pathways GO:0051289| protein homotetramerization CAT;RXRA;TRPA1;CRYZ;TRPM8;TRPV1 GO:0016032| viral reproduction HTR2A;VDAC1;RXRA GO:0007507| heart development PPARG;RXRA GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;RXRA GO:0043401| steroid hormone mediated signaling pathway RXRA;PPARG GO:0006351| transcription, DNA-dependent NCOA2;PPARG;RXRA GO:0001890| placenta development SOD1;RXRA;PPARG GO:0032870| cellular response to hormone stimulus CACNA1H;NCOA2 GO:0043010| camera-type eye development RXRA;CYP1A1 GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;NCOA2;CYP1A1;PPARG;RXRA GO:0007566| embryo implantation RXRA;PTGS2;SOD1 GO:0035357| peroxisome proliferator activated receptor signaling pathway RXRA;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;RXRA GO:0006355| regulation of transcription, DNA-dependent NCOA2;RXRA;PPARG GO:0045893| positive regulation of transcription, DNA-dependent RXRA;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;RXRA;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter RXRA;PPARG;NCOA2;TRPV4;TRPV1 GO:0008203| cholesterol metabolic process RXRA;HMGCR;CAT GO:0007623| circadian rhythm NCOA2;AANAT GO:0032526| response to retinoic acid RXRA;PPARG GO:0048511| rhythmic process NCOA2;PPARG;AANAT GO:0045892| negative regulation of transcription, DNA-dependent NCOA2;PPARG 20929:[DB14011 DB07645] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways GO:0008217| regulation of blood pressure PPARG;HBB;PTGS2;SOD1;PTGS1 GO:0051291| protein heterooligomerization GLRA1;HBB;HBA1;GLRB GO:0042542| response to hydrogen peroxide HBA1;HBB;TRPA1;CAT;GPX1;SOD1 GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HBB GO:0098869| PTGS2;GPX1;PTGS1;CAT;HBA1;HBB;GSR GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;HBA1;HBB GO:0043312| neutrophil degranulation ALOX5;CAT;HBB 20930:[DB14011 DB04660] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04660|Choline alfoscerate GM2A common genes common pathways GO:0006629| lipid metabolic process HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;GPX1;NAAA;PTGS1;GM2A;CYP2C9;PPARG;PLA2G1B;TRPV1;DAGLA;CYP2D6;ALOX15 GO:0006687| glycosphingolipid metabolic process GM2A;SMPD1 GO:0007611| learning or memory GM2A;CNR1;CHRNA7 GO:0043312| neutrophil degranulation GM2A;ALOX5;CAT 20931:[DB14011 DB00073] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00073|Rituximab MS4A1 common genes common pathways 20932:[DB14011 DB06494] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06494|Sufugolix GNRHR common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;GNRHR GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;GPR55;HTR1A;CACNA1I;PLA2G1B;GNRHR;SMPD1;GPR18;PPARG 20933:[DB14011 DB07108] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways GO:0090201| negative regulation of release of cytochrome c from mitochondria GPX1;BCL2L1 GO:1902042| GPX1;BCL2L1 GO:0051881| regulation of mitochondrial membrane potential BCL2L1;OPRD1;SOD1 GO:0008283| cell proliferation GPX1;HTR1A;BCL2L1;CYP1A1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;BCL2L1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0071312| cellular response to alkaloid TRPV1;BCL2L1 GO:0009314| response to radiation BCL2L1;PTGS2;OPRM1;CAT GO:0043524| negative regulation of neuron apoptosis BCL2L1;SOD1 GO:0007283| spermatogenesis BCL2L1;SOD1;CNR1 GO:0006915| apoptotic process GPX1;VDAC1;BCL2L1 GO:0001541| ovarian follicle development SOD1;BCL2L1 GO:0034097| response to cytokine stimulus BCL2L1;PTGS2;AANAT GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;BCL2L1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR;BCL2L1 GO:0009615| response to virus CYP1A1;BCL2L1 GO:0071230| cellular response to amino acid stimulus BCL2L1;GLRA1 20934:[DB14011 DB08642] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;GPX1;ALOX5;PTGS1;CYP2C9;CYP1A1;CRYZ;DHFR;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1B1 20935:[DB14011 DB09409] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways GO:0006812| cation transport GRIN1;TRPM8 GO:0006811| ion transport GRIN2A;CHRNA7;TRPV2;GLRA3;GRIN2B;TRPV3;GRIN2D;GRIN1;CACNA1H;TRPM8;VDAC1;GRIN3B;TRPV4;CACNA1I;GLRB;TRPV1;GLRA1;TRPA1;GRIN3A;CACNA1G;GRIN2C GO:0051930| regulation of sensory perception of pain GRIN2A;GRIN2D;OPRM1;OPRD1 GO:0008344| adult locomotory behavior OPRD1;GRIN1;GRIN2D GO:1900273| GRIN2A;CHRNA7 GO:0070588| calcium ion transmembrane transport TRPV1;TRPV4;GRIN3B;CACNA1I;TRPM8;CACNA1G;GRIN3A;TRPA1;TRPV2;CHRNA7;OPRM1;CACNA1H;TRPV3 GO:0065009| regulation of molecular function GRIN2C;TRPV1;GRIN2B;GRIN1;GRIN2D;GRIN2A GO:0001975| response to amphetamine GRIN2A;CNR2;GRIN1;SOD1 GO:0022008| neurogenesis GRIN2A;DAGLA GO:0007613| memory PTGS2;GRIN1;CNR1;HTR2A;GRIN2A;CHRNA7 GO:0043576| regulation of respiratory gaseous exchange GLRA1;GRIN1 GO:0006816| calcium ion transport TRPV3;CACNA1H;GRIN1;TRPV2;CHRNA7;GRIN2A;CACNA1G;TRPA1;GRIN3A;TRPV1;CACNA1I;TRPV4;TRPM8 GO:0001964| startle response GRIN2A;GRIN1;GRIN2D;GLRB;GLRA1 GO:0008542| visual learning GRIN1;HMGCR;GRIN2A GO:0051924| regulation of calcium ion transport OPRD1;GRIN3B GO:0007268| synaptic transmission GRIN2A;GRIN2B;HTR2A;GLRA3;OPRM1;OPRD1;VDAC1;GLRB;GLRA1;CACNA1G GO:0043524| negative regulation of neuron apoptosis GRIN1;SOD1 GO:0042428| serotonin metabolic process GRIN2A;HTR1A GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2;GRIN1;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GRIN2A GO:0030431| sleep CACNA1I;HTR2A;GRIN2A;SLC29A1 GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR1;HTR2A;OPRM1;GRIN1;PTGS2;CNR2;OPRD1;GRIN2A GO:0045471| response to ethanol GRIN3A;SOD1;CNR1;GRIN2B;HMGCR;GRIN1;OPRM1;GRIN2A;CAT GO:2000463| positive regulation of excitatory postsynaptic membrane potential GRIN1;CHRNA7 GO:0034220| ion transmembrane transport TRPV1;GLRB;GRIN3B;GRIN3A;TRPA1;GLRA1;CHRNA7;GLRA3 GO:0006874| cellular calcium ion homeostasis CHRNA7;GPR12;HTR2A;GRIN1;TRPM8;TRPV4 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;GRIN2C;GRIN2A;GRIN1;CACNA1H GO:0009611| response to wounding GRIN2C;CYP1A1;GPX1;GRIN2A GO:0006810| transport TRPV2;GRIN2A;GRIN2B;TRPV1;CACNA1I;ABCG2;ABCC1;GRIN2C GO:0043278| response to morphine GRIN1;OPRM1;CNR1 GO:0050905| neuromuscular process GRIN1;GLRA1;GLRB GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;GRIN2A;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;PLA2G1B;PPARG GO:0043523| regulation of neuron apoptosis GRIN1;GPX1 GO:0007611| learning or memory CNR1;GRIN2B;GRIN1;GRIN2A;CHRNA7 GO:0007612| learning GRIN2A;PTGS2;GRIN1;VDAC1 GO:0010524| positive regulation of calcium ion transport into cytosol GRIN1;PLA2G1B GO:0060079| regulation of excitatory postsynaptic membrane potential GRIN2C;GLRA1;GRIN3A;TRPV1;GRIN3B;GLRB;OPRM1;GRIN2D;GRIN1;GLRA3;GRIN2B;SLC29A1;CHRNA7;GRIN2A 20936:[DB14011 DB00048] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;COL1A1;SOD1;HTR2A;CYP1A2;PTGS2;CAT GO:0045893| positive regulation of transcription, DNA-dependent PPARG;COL1A1 GO:0055093| response to hyperoxia CAT;COL1A1;CYP1A1 GO:0071230| cellular response to amino acid stimulus COL1A2;COL1A1;COL3A1;GLRA1 GO:0030199| collagen fibril organization COL1A2;COL2A1;CYP1B1;COL1A1;COL3A1 GO:0071306| cellular response to vitamin E COL1A1;PPARG GO:0042060| wound healing OPRM1;COL1A1;COL3A1;ALOX15 GO:0034097| response to cytokine stimulus PTGS2;AANAT;COL3A1 GO:0009612| response to mechanical stimulus PPARG;COL3A1;COL1A1;TRPV4 GO:0071300| cellular response to retinoic acid COL1A1;PPARG GO:0051591| response to cAMP COL1A1;AANAT GO:0071356| cellular response to tumor necrosis factor COL1A1;TRPV1 GO:0010468| regulation of gene expression COL2A1;CYP1A2 GO:0035025| positive regulation of Rho protein signal transduction COL3A1;GPR18;GPR55 GO:0007568| aging CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;COL3A1 GO:0032355| response to estradiol stimulus COL1A1;CYP1A2;PTGS2;CAT GO:0007605| sensory perception of sound COL1A1;GPX1;SOD1;COL2A1 GO:0031667| response to nutrient levels COL1A1;SOD1 GO:0048565| digestive tract development COL3A1;CYP1A1 GO:0007507| heart development COL3A1;PPARG GO:0001503| ossification COL1A1;ALOX15;COL2A1 GO:0071260| cellular response to mechanical stimulus COL1A1;PTGS2 GO:0042542| response to hydrogen peroxide SOD1;GPX1;CAT;TRPA1;COL1A1 GO:0009314| response to radiation COL3A1;CAT;PTGS2;OPRM1 GO:0060351| cartilage development involved in endochondral bone morphogenesis COL2A1;COL1A1;TRPV4 GO:0007584| response to nutrient PPARG;COL1A1;CNR1;HMGCR GO:0008217| regulation of blood pressure PTGS2;SOD1;COL1A2;PTGS1;PPARG GO:0001649| osteoblast differentiation COL1A1;CAT GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1;COL1A1;COL2A1 GO:0043434| response to peptide hormone stimulus TRPV1;COL1A1 20937:[DB14011 DB00102] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00102|Becaplermin PDGFRB;PDGFRA;A2M common genes common pathways GO:0043627| response to estrogen stimulus PDGFRB;PPARG GO:0090280| positive regulation of calcium ion import TRPV3;TRPV2;PDGFRB GO:0045740| positive regulation of DNA replication PLA2G1B;PDGFRA GO:0048146| positive regulation of fibroblast proliferation PDGFRA;PLA2G1B;PDGFRB GO:0009636| response to toxin CYP1A1;PDGFRB;CYP1B1;CAT;GPX1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1;PDGFRB GO:0007165| signal transduction SMPD1;PPARG;PDGFRB;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;PDGFRA;TRPV4;TRPV1 GO:0016032| viral reproduction PDGFRA;VDAC1;HTR2A GO:0042542| response to hydrogen peroxide PDGFRB;TRPA1;GPX1;CAT;SOD1 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PDGFRB;PPARG;SMPD1 GO:0035556| intracellular signal transduction PLA2G1B;PDGFRB GO:0043406| positive regulation of MAP kinase activity PDGFRB;HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;PDGFRB;ALOX15;TRPV4;PDGFRA GO:0033993| response to lipid PDGFRB;PPARG GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade PDGFRB;PDGFRA;CAT GO:0035025| positive regulation of Rho protein signal transduction GPR55;GPR18;PDGFRB GO:0007568| aging HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;PDGFRB GO:0007186| G-protein coupled receptor signaling pathway GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GPR18;PPARG;PDGFRB GO:0032355| response to estradiol stimulus PDGFRB;CYP1A2;PTGS2;CAT GO:0061298| retina vasculature development in camera-type eye PDGFRB;PDGFRA;CYP1B1 GO:0060326| cell chemotaxis PDGFRB;ABCC1;PDGFRA GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRA;PDGFRB;GPX1 GO:0055093| response to hyperoxia CAT;PDGFRB;CYP1A1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;PDGFRB GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7;PDGFRB;PDGFRA GO:0002576| platelet degranulation SOD1;A2M GO:0043066| negative regulation of apoptotic process PDGFRB;PTGS2;HMGCR;SOD1;GPX1;CAT GO:0032526| response to retinoic acid PPARG;PDGFRB GO:0042060| wound healing PDGFRB;ALOX15;PDGFRA;OPRM1 20938:[DB14011 DB06967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06967|6-ETHYL-5-[9-(3-METHOXYPROPYL)-9H-CARBAZOL-2-YL]PYRIMIDINE-2,4-DIAMINE REN common genes common pathways GO:0051591| response to cAMP AANAT;REN GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CYP1A1;PPARG;TRPA1;REN GO:0042493| response to drug REN;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;CYP1A1;REN;IDO1 GO:0001822| kidney development CAT;REN GO:0035902| response to immobilization stress CYP1A2;REN;PPARG;CYP1A1 GO:0008217| regulation of blood pressure REN;PPARG;PTGS1;SOD1;PTGS2 GO:0048469| cell maturation PPARG;REN 20939:[DB14011 DB02910] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02910|Octanoyl-Coenzyme A ECHS1;ECI1;ACADM common genes common pathways GO:0019216| regulation of lipid metabolic process ACADM;PPARG;CYP1A1;HMGCR;CNR1 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;DAGLA;ECHS1;CYP2D6;ALOX15;ACADM;CYP2C9;PPARG;GPX1;NAAA;PTGS1;ECI1;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4 GO:0008152| metabolic process ACAT1;ECI1;ECHS1;SMPD1;ACADM GO:0055114| oxidation-reduction process CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP2C9;CYP1A1;CRYZ;ACADM;CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR GO:0006631| fatty acid metabolic process ECHS1;ALOX15;ACADM;PTGS1;ECI1;PTGS2 GO:0006635| fatty acid beta-oxidation ACAT1;ECI1;ECHS1;ACADM 20940:[DB14011 DB02830] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02830|FR236913 ADA common genes common pathways GO:0030324| lung development CYP1A2;ADA GO:0033197| response to vitamin E CAT;ADA GO:0007155| cell adhesion ADA;CYP1B1 GO:0043066| negative regulation of apoptotic process ADA;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0042493| response to drug TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT;ADA GO:0043278| response to morphine OPRM1;CNR1;ADA GO:0050728| negative regulation of inflammatory response CNR2;ADA GO:0007568| aging CYP1A1;CAT;ADA;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PTGS2 GO:0001666| response to hypoxia CYP1A1;ADA;CHRNA7;CAT GO:0001889| liver development CYP1A1;ADA;ACAT1 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;ADA;CAT;SOD1 GO:0001890| placenta development PPARG;SOD1;ADA GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 20941:[DB14011 DB02388] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02388|Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine MAPK10 common genes common pathways GO:0042752| regulation of circadian rhythm MAPK10;PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;MAPK10;SMPD1;PPARG;GPR18;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0009416| response to light stimulus MAPK10;AANAT GO:0048511| rhythmic process AANAT;MAPK10;PPARG GO:0000187| activation of MAPK activity MAPK10;PLA2G1B;CHRNA7;SOD1 GO:0010468| regulation of gene expression CYP1A2;MAPK10 20942:[DB14011 DB03127] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03127|Benzamidine KLK6;PRSS2;PRSS3;ATOX1;ECI1;ST14;PLAU;PRSS1;CSNK2A1;KLK1 common genes common pathways GO:0016236| macroautophagy CSNK2A1;VDAC1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0006631| fatty acid metabolic process ECI1;PTGS2;PTGS1;ALOX15 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;CSNK2A1;HTR1A;HTR2A;CHRNA7 GO:0043312| neutrophil degranulation PRSS2;PLAU;PRSS3;CAT;ALOX5 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PLAU GO:0006635| fatty acid beta-oxidation ACAT1;ECI1 GO:0043542| endothelial cell migration PRSS3;CYP1B1 GO:0001666| response to hypoxia CYP1A1;PLAU;CAT;CHRNA7 GO:0048511| rhythmic process CSNK2A1;AANAT;PPARG GO:0006915| apoptotic process GPX1;CSNK2A1;VDAC1 GO:0006979| response to oxidative stress ATOX1;SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0009235| cobalamin metabolic process PRSS3;ABCC1;PRSS1 GO:0009611| response to wounding KLK6;GPX1;CYP1A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1;GPX1 GO:0008152| metabolic process SMPD1;ECI1;ACAT1 GO:0006629| lipid metabolic process CYP2C9;PPARG;DAGLA;CYP2D6;ALOX15;PLA2G1B;TRPV1;NAPEPLD;CYP3A4;HMGCR;ECI1;CYP1A2;PTGS2;NAAA;PTGS1;GPX1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0006811| ion transport TRPM8;ATOX1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;CSNK2A1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CACNA1I;PLA2G1B;PLAU;SMPD1;PPARG;GPR18 20943:[DB14011 DB04581] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04581|1-benzylimidazole QPCT common genes common pathways GO:0043312| neutrophil degranulation ALOX5;CAT;QPCT 20944:[DB14011 DB02046] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02046|N-[(Furan-2-Yl)Carbonyl]-(S)-Leucyl-(R)-[1-Amino-2(1h-Indol-3-Yl)Ethyl]-Phosphonic Acid ADAM28 common genes common pathways GO:0007283| spermatogenesis ADAM28;SOD1;CNR1 20945:[DB14011 DB02989] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02989|CRA_10972 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 20946:[DB14011 DB00068] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00068|Interferon beta-1b IFNAR1;IFNAR2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNAR2 GO:0032496| response to lipopolysaccharide CYP1A2;IFNAR1;OPRM1;CNR2;PTGS2;CNR1;IDO1;CYP1A1 GO:0009615| response to virus IFNAR2;IFNAR1;CYP1A1 20947:[DB14011 DB08378] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08378|4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID MYL6B;MYL12A;MYH7 common genes common pathways GO:0002027| regulation of heart rate CACNA1G;MYH7 GO:0006936| muscle contraction MYL12A;GLRA1;MYH7;CACNA1H;MYL6B 20948:[DB14011 DB01699] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0001666| response to hypoxia ABAT;CYP1A1;CAT;CHRNA7 GO:0042220| response to cocaine ABAT;SMPD1;OPRM1;CNR1 GO:0007568| aging HTR2A;SOD1;CNR1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;ABAT GO:0035640| exploration behavior ABAT;HTR1A GO:0035094| response to nicotine ABAT;CHRNA7;CNR1 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABAT;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0033602| negative regulation of dopamine secretion CNR1;ABAT GO:0007626| locomotory behavior ABAT;OPRM1;SOD1 GO:0048148| behavioral response to cocaine ABAT;HTR2A GO:0045471| response to ethanol ABAT;CNR1;SOD1;HMGCR;OPRM1;CAT GO:0045776| negative regulation of blood pressure CNR1;ABAT 20949:[DB14011 DB06937] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG GO:0006351| transcription, DNA-dependent PPARG;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG GO:0007165| signal transduction GPR18;PPARG;SMPD1;ESR2;PLA2G1B;CACNA1I;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;OPRM1;CNR2;CHRNA7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;PLA2G1B;PPARG GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2 20950:[DB14011 DB07800] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07800|N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 20951:[DB14011 DB08169] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0031000| response to caffeine PPARG;DHODH GO:0042594| response to starvation PPARG;ACAT1;DHODH GO:0042493| response to drug ABCG2;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;CAT;DHODH;CYP1A2;PTGS2;HTR2A;SOD1 GO:0055114| oxidation-reduction process ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CRYZ;CAT;DHODH;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR GO:0014070| response to organic cyclic compound DHODH;ACAT1;AANAT;PTGS2;CYP1A2;TRPA1;PPARG;CYP1A1 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;DHODH;CNR1;SOD1;PTGS2 GO:0007565| female pregnancy DHODH;IDO1 GO:0007595| lactation SLC29A1;DHODH 20952:[DB14011 DB06263] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB5 GO:0007584| response to nutrient POR;PPARG;HMGCR;CNR1 GO:0019395| fatty acid oxidation POR;PPARG GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB5 GO:0006805| xenobiotic metabolic process CYP2C9;POR;CYP1B1;CYP3A5;CYP2D6;CYP2C19;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;TOP2A;PPARG GO:0070988| demethylation POR;CYP1A1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process POR;GPX1;PTGS2 GO:0019371| cyclooxygenase pathway CBR1;PTGS1;PTGS2 GO:0017144| drug metabolic process CBR1;CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0042391| regulation of membrane potential GLRA1;CACNA1G;GLRB;CACNA1H;ABCB5 GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG;CBR1 GO:0055085| transmembrane transport CACNA1H;TRPV3;ABCB5;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;TRPV4;CACNA1I;TRPV1 GO:0043066| negative regulation of apoptotic process POR;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;PPARG;PLA2G1B GO:0009812| flavonoid metabolic process CYP1A1;POR GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;POR;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;ALOX5;PTGS1;GPX1;CBR1;CAT GO:0022900| electron transport chain CYP1A2;POR;GSR;IDO1 GO:0042493| response to drug CAT;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;POR;TRPA1;PPARG;CYP1A1;ABCC1;SMPD1 20953:[DB14011 DB08709] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08709|2,3-diphenyl-1H-indole-7-carboxylic acid PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PIM1;HMGCR;SOD1;GPX1;CAT GO:0006915| apoptotic process GPX1;PIM1;VDAC1 GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;PIM1 20954:[DB14011 DB03725] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways GO:0032869| cellular response to insulin stimulus PCK1;PLA2G1B;PPARG GO:0014823| response to activity CAT;PCK1 GO:0032868| response to insulin stimulus TRPV4;CAT;PCK1;AANAT GO:0006629| lipid metabolic process PCK1;NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0071320| cellular response to cAMP AANAT;PCK1 GO:0033993| response to lipid PPARG;PCK1 GO:0042593| glucose homeostasis TRPV4;PPARG;PCK1;CNR1 GO:0007568| aging CYP1A1;CAT;PCK1;PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;PCK1;SLC29A1 GO:0071356| cellular response to tumor necrosis factor TRPV1;PCK1 GO:0071300| cellular response to retinoic acid PPARG;PCK1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;PCK1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 20955:[DB14011 DB06938] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06938|4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide KDR common genes common pathways GO:0045766| positive regulation of angiogenesis KDR;CYP1B1;CHRNA7 GO:0070374| positive regulation of ERK1 and ERK2 cascade GPR55;HTR2A;OPRM1;HMGCR;CHRNA7;ALOX15;TRPV4;KDR GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade KDR;CAT GO:0043066| negative regulation of apoptotic process KDR;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;KDR GO:0010629| negative regulation of gene expression KDR;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;KDR GO:0016032| viral reproduction HTR2A;VDAC1;KDR GO:0001525| angiogenesis PTGS2;CYP1B1;KDR 20956:[DB14011 DB08301] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08301|N-({[4-(AMINOSULFONYL)PHENYL]AMINO}CARBONYL)-4-METHYLBENZENESULFONAMIDE CA2 common genes common pathways GO:0010043| response to zinc ion AANAT;CA2 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH TRPV1;CA2 GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0001822| kidney development CA2;CAT 20957:[DB14011 DB06809] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06809|Plerixafor CXCR4 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CXCR4;PPARG;GPR18 GO:0048714| positive regulation of oligodendrocyte differentiation CXCR4;PPARG GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;CXCR4 GO:0006915| apoptotic process GPX1;VDAC1;CXCR4 GO:0000187| activation of MAPK activity PLA2G1B;CXCR4;CHRNA7;SOD1 GO:0009615| response to virus CXCR4;CYP1A1 GO:0007165| signal transduction CHRNA7;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;CXCR4;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0007204| elevation of cytosolic calcium ion concentration CXCR4;TRPV4;TRPV1;HTR2A;OPRM1 GO:0071345| cellular response to cytokine stimulus TRPV1;CXCR4 GO:0016032| viral reproduction VDAC1;CXCR4;HTR2A GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;TRPV1;ALOX15;IDO1;CXCR4 20958:[DB14011 DB02740] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02740|3-Indolebutyric Acid tyrB;B2M;TRAC;TRBC1;HLA-A common genes common pathways GO:0061844| B2M;PLA2G1B GO:0001895| retina homeostasis B2M;SOD1 GO:0016032| viral reproduction VDAC1;HLA-A;HTR2A GO:0006955| immune response CNR2;OPRD1;HLA-A;TRBC1;B2M GO:0010977| negative regulation of neuron projection development TRPV4;B2M GO:0046686| response to cadmium ion B2M;CAT GO:0002376| immune system process HLA-A;IDO1;B2M GO:0042493| response to drug CAT;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;TRPA1;B2M;CYP1A1;PPARG;ABCC1;SMPD1 GO:0050830| defense response to Gram-positive bacterium B2M;PLA2G1B GO:0019731| antibacterial humoral response PLA2G1B;B2M GO:0043312| neutrophil degranulation ALOX5;CAT;B2M GO:0045087| innate immune response TRBC1;PPARG;B2M 20959:[DB14011 DB03173] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03173|CRA_10433 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 20960:[DB14011 DB02165] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways GO:0042178| xenobiotic catabolic process CRYZ;GSTM1 GO:0006749| glutathione metabolic process SOD1;GPX1;GSTM1;GSR GO:0008152| metabolic process ACAT1;GSTM1;SMPD1 20961:[DB14011 DB01082] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways GO:0045087| innate immune response PADI4;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;PADI4 GO:0051260| protein homooligomerization GLRA3;ACAT1;GLRA1;SLC22A6 GO:0002376| immune system process PADI4;IDO1 GO:0006820| anion transport SLC22A6;GLRA1;VDAC1 GO:0055085| transmembrane transport SLC22A6;CACNA1G;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 GO:0006351| transcription, DNA-dependent PPARG;PADI4 GO:0098656| VDAC1;SLC22A6 20962:[DB14011 DB02824] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways GO:0051289| protein homotetramerization TRPV1;TRPM8;CRYZ;TRPA1;CAT;SHMT1 GO:0001822| kidney development CAT;ODC1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;ODC1;CHRNA7 GO:0009615| response to virus CYP1A1;ODC1 GO:0051262| protein tetramerization CAT;SHMT1;HMGCR 20963:[DB14011 DB06757] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG;ARG1 GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0010043| response to zinc ion AANAT;ARG1 GO:0009791| post-embryonic development CYP1A2;ACO1 GO:0001895| retina homeostasis TF;SOD1 GO:0010269| response to selenium ion GPX1;ARG1 GO:0006811| ion transport TRPM8;TRPV1;VDAC1;TRPV4;GLRB;CACNA1I;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GLRA3;TF;TRPV3;CACNA1H GO:0043434| response to peptide hormone stimulus ARG1;TRPV1 GO:0006879| cellular iron ion homeostasis ABCG2;ACO1;SOD1;TF GO:0051092| positive regulation of NF-kappaB transcription factor activity TAB1;PLA2G1B;CAT GO:0007565| female pregnancy IDO1;ARG1 GO:0009635| response to herbicide ARG1;CYP1A1 GO:0008152| metabolic process ACAT1;SMPD1;ACO1 GO:0048678| response to axon injury ARG1;SOD1 GO:0001889| liver development CYP1A1;ACAT1;ARG1 GO:0042130| negative regulation of T cell proliferation IDO1;ARG1 GO:0043406| positive regulation of MAP kinase activity HTR2A;TAB1 GO:0000187| activation of MAPK activity SOD1;CHRNA7;TAB1;PLA2G1B GO:0043200| response to amino acid stimulus GLRA3;ARG1;GLRB GO:0046686| response to cadmium ion CAT;ARG1 GO:0002376| immune system process ARG1;IDO1 GO:0007568| aging ARG1;CAT;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CYP1A1 GO:0010468| regulation of gene expression ACO1;CYP1A2 GO:0009611| response to wounding CYP1A1;ARG1;GPX1 GO:0033189| response to vitamin A CYP1A1;PPARG;ARG1;CAT GO:0010042| response to manganese ion PTGS2;ARG1 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;SOD1;GPX1;ALOX5;PTGS1;CAT;CYP2C9;CYP1A1;CRYZ;CYP1B1;IDH3G;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;IDH3A GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;ARG1;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2 GO:0043312| neutrophil degranulation ARG1;CAT;ALOX5 GO:0045087| innate immune response ARG1;PPARG GO:0002576| platelet degranulation SOD1;TF GO:0070207| protein homotrimerization TRPM8;ARG1 GO:0030324| lung development ARG1;CYP1A2;TAB1 GO:0060135| maternal process involved in female pregnancy CNR1;ARG1 GO:0033197| response to vitamin E CAT;ARG1 GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;PTGS2;CNR2;CNR1;ARG1;CYP1A1;IDO1 20964:[DB14011 DB06878] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06878|1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0009611| response to wounding GPX1;CYP1A1;F2 GO:0007186| G-protein coupled receptor signaling pathway F2;GPR18;PPARG;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0061844| PLA2G1B;F2 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 20965:[DB14011 DB14526] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14526|Chromic citrate CYB5A;TF common genes common pathways GO:0046686| response to cadmium ion CAT;CYB5A GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;ALOX5;GPX1;PTGS1;CAT;CYP1A2;PTGS2;CYB5A;CYP3A7;HMGCR;CYP3A4;SOD1 GO:0022900| electron transport chain IDO1;GSR;CYP1A2;CYB5A GO:0002576| platelet degranulation SOD1;TF GO:0001895| retina homeostasis TF;SOD1 GO:0006811| ion transport VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TF;TRPV3;CACNA1H;GLRA3 GO:0006879| cellular iron ion homeostasis ABCG2;TF;SOD1 20966:[DB14011 DB01140] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A5 GO:0006811| ion transport TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;SLC15A1;CACNA1G;CHRNA7;TRPV2;SLC22A8;GLRA3;SLC22A5;SLC15A2;TRPV3;CACNA1H GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0098656| VDAC1;SLC22A6;SLC22A8 GO:0006810| transport CACNA1I;TRPV1;ABCG2;ABCC1;SLC15A1;TRPV2;SLC15A2 GO:0006820| anion transport VDAC1;SLC22A6;GLRA1 GO:0051260| protein homooligomerization GLRA1;SLC22A6;GLRA3;ACAT1 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC22A5;SLC15A2;SLC22A8;TRPV2;ABCC1;SLC22A6;CACNA1G;SLC15A1;TRPA1;TRPV1;CACNA1I;TRPV4;VDAC1;TRPM8;ABCG2 20967:[DB14011 DB00121] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes CYP1B1 common pathways GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0043542| endothelial cell migration CYP1B1 GO:0030199| collagen fibril organization CYP1B1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0007155| cell adhesion CYP1B1 GO:0006631| fatty acid metabolic process PTGS1;ACACB;PTGS2;ACACA;ALOX15 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0042493| response to drug CAT;ACACB;HTR2A;SOD1;PTGS2;CYP1A2;ABCG2;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1 GO:0055114| oxidation-reduction process SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;GPX1;ALOX5;PTGS1;CRYZ;CYP2C9;CYP1A1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;CYP2D6;DAGLA;ALOX15 GO:0009083| branched chain family amino acid catabolic process ACAT1;MCCC2;MCCC1 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0061298| retina vasculature development in camera-type eye CYP1B1 GO:0008210| estrogen metabolic process CYP1B1 GO:0009062| fatty acid catabolic process FAAH;PCCB GO:0008202| steroid metabolic process CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP1B1 GO:0006810| transport TRPV1;CACNA1I;ABCG2;SLC5A6;ABCC1;TRPV2 GO:0048514| blood vessel morphogenesis CYP1B1 GO:0042574| retinal metabolic process CYP1B1 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0045766| positive regulation of angiogenesis CHRNA7;CYP1B1 GO:0055085| transmembrane transport TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;SLC5A6;CACNA1G;ABCC1;TRPA1;TRPV2;CACNA1H;TRPV3 GO:0045540| regulation of cholesterol biosynthetic process ACACA;HMGCR;ACACB GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0016125| sterol metabolic process CYP1B1;CYP17A1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0008152| metabolic process SMPD1;ACAT1;ACACB;PC;HLCS;ACACA GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 GO:0042572| retinol metabolic process CYP1B1 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;CYP2C9;PPARG;GPX1;NAAA;PTGS1;PC;ACACB;HMGCR;CYP1A2;PTGS2;ACACA;NAPEPLD;CYP3A4 GO:0031667| response to nutrient levels ACACB;SOD1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0010629| negative regulation of gene expression ACACB;PC;OPRD1 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1 GO:0051289| protein homotetramerization TRPA1;CRYZ;TRPM8;TRPV1;ACACA;CAT;ACACB GO:0015936| coenzyme A metabolic process HMGCR;MCCC2;ACAT1 GO:0031999| negative regulation of fatty acid beta-oxidation CNR1;ACACB GO:0007601| visual perception CYP1B1;GLRB;CRYZ;GLRA1 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;ACACB;ACACA;PTGS2 GO:0009636| response to toxin CYP1A1;CYP1B1;GPX1;CAT GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;CYP1A2;PTGS2;ACACB;AANAT;ACAT1 GO:0008283| cell proliferation HTR1A;HLCS;GPX1;CYP1A1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CYP1B1;CAT GO:0006811| ion transport CHRNA7;TRPV2;GLRA3;CACNA1H;TRPV3;TRPM8;SLC5A6;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;GLRA1;TRPA1;CACNA1G GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0002930| CYP1B1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0051291| protein heterooligomerization GLRB;GLRA1;MCCC2;MCCC1 GO:0055088| lipid homeostasis PPARG;ACACA GO:0071380| cellular response to prostaglandin E stimulus PPARG;ACACA GO:0030336| negative regulation of cell migration CYP1B1 GO:0046466| membrane lipid catabolic process CYP1B1 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;PTGS2;OPRM1 GO:0070301| cellular response to hydrogen peroxide CYP1B1 20968:[DB14011 DB05432] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05432|DAS-431 IV CALY common genes common pathways 20969:[DB14011 DB03443] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03443|Bis(5-Amidino-Benzimidazolyl)Methanone Zinc PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 20970:[DB14011 DB05389] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways GO:0006954| inflammatory response ALOX5;PTGS1;CD163;PTGS2;CNR2;ALOX15;IDO1;TRPV1 GO:0007155| cell adhesion CYP1B1;MAEA 20971:[DB14011 DB04901] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04901|Galiximab CD80 common genes common pathways GO:0046718| entry of virus into host cell CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction HTR2A;CD80;VDAC1 GO:0035556| intracellular signal transduction CD80;PLA2G1B GO:0051897| positive regulation of protein kinase B signaling cascade CD80;GPX1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARG 20972:[DB14011 DB06393] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06393|Xaliproden HTR1A common genes HTR1A common pathways GO:0050795| regulation of behavior HTR1A;HTR2A GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 GO:0035640| exploration behavior HTR1A GO:0007210| serotonin receptor signaling pathway HTR1A;HTR2A GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;GPR18;PPARG GO:0014062| regulation of serotonin secretion HTR1A GO:0042310| vasoconstriction HTR1A GO:0042428| serotonin metabolic process HTR1A GO:0007165| signal transduction GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I;CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7 GO:0007610| behavior HTR2A;HTR1A GO:0046883| regulation of hormone secretion HTR2A;HTR1A GO:0001662| behavioral fear response VDAC1;HTR1A GO:0042053| regulation of dopamine metabolic process HTR1A GO:0007198| inhibition of adenylate cyclase activity by serotonin receptor signaling pathway HTR1A GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 20973:[DB14011 DB04173] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04173|Fructose FHIT common genes common pathways GO:0006915| apoptotic process VDAC1;FHIT;GPX1 GO:0006355| regulation of transcription, DNA-dependent FHIT;PPARG GO:0006351| transcription, DNA-dependent FHIT;PPARG 20974:[DB14011 DB04213] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2C9;EPHX2;CYP1A2 GO:0010628| positive regulation of gene expression EPHX2;TRPV4 GO:0006874| cellular calcium ion homeostasis EPHX2;GPR12;HTR2A;CHRNA7;TRPV4;TRPM8 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;EPHX2;CYP3A4;CYP1A2 GO:0006954| inflammatory response EPHX2;PTGS2;CNR2;ALOX5;PTGS1;ALOX15;IDO1;TRPV1 GO:0008152| metabolic process EPHX2;ACAT1;SMPD1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;EPHX2;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;EPHX2;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0009636| response to toxin CYP1B1;CYP1A1;CAT;GPX1;EPHX2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;EPHX2;SOD1;PPARG GO:0072593| reactive oxygen species metabolic process SOD1;EPHX2 20975:[DB14011 DB02869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02869|3-amino-5-phenylpentane CTSV;CTSK common genes common pathways GO:0007283| spermatogenesis CNR1;SOD1;CTSV GO:1903146| VDAC1;CTSK GO:0046697| decidualization CTSV;PTGS2 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CTSV;TRPA1;PPARG;CYP1A1 GO:0045453| bone resorption GPR55;CTSK GO:0051384| response to glucocorticoid stimulus CTSV;PTGS2 20976:[DB14011 DB03722] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03722|3,4-Dihydro-5-Methyl-Isoquinolinone PARP1 common genes common pathways GO:0006351| transcription, DNA-dependent PPARG;PARP1 GO:0071294| cellular response to zinc ion PARP1;GLRA1 GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B;PARP1 GO:0010332| response to gamma radiation PARP1;GPX1 GO:0006355| regulation of transcription, DNA-dependent PARP1;PPARG GO:0034599| cellular response to oxidative stress CAT;GPX1;SOD1;PARP1;GSR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;PARP1 GO:0006915| apoptotic process PARP1;GPX1;VDAC1 20977:[DB14011 DB07232] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07232|Veliparib PARP1;PARP2 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PARP1;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;PARP1 GO:0034599| cellular response to oxidative stress SOD1;PARP1;CAT;GPX1;GSR GO:0006355| regulation of transcription, DNA-dependent PPARG;PARP1 GO:0006915| apoptotic process PARP1;GPX1;VDAC1 GO:0006351| transcription, DNA-dependent PARP1;PPARG GO:0071294| cellular response to zinc ion PARP1;GLRA1 GO:0010332| response to gamma radiation PARP1;GPX1 GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG;PARP1 20978:[DB14011 DB05855] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05855|Rivanicline CHRNB2;CXCL8 common genes common pathways GO:0006954| inflammatory response PTGS2;CNR2;ALOX5;PTGS1;TRPV1;CXCL8;ALOX15;IDO1 GO:0006955| immune response CXCL8;OPRD1;CNR2 GO:0006816| calcium ion transport TRPV1;TRPV4;CACNA1I;TRPM8;CHRNB2;CACNA1G;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3 GO:0008542| visual learning CHRNB2;HMGCR GO:0035556| intracellular signal transduction CXCL8;PLA2G1B GO:0060078| regulation of postsynaptic membrane potential CHRNB2;CHRNA7 GO:0045471| response to ethanol CHRNB2;HMGCR;OPRM1;SOD1;CNR1;CAT GO:0001525| angiogenesis CXCL8;CYP1B1;PTGS2 GO:0019233| sensory perception of pain OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A;TRPV1;CHRNB2;TRPA1 GO:0042053| regulation of dopamine metabolic process CHRNB2;HTR1A GO:0034976| response to endoplasmic reticulum stress CXCL8;ALOX15 GO:0051291| protein heterooligomerization GLRA1;CHRNB2;GLRB GO:0061844| CXCL8;PLA2G1B GO:0008285| negative regulation of cell proliferation CYP1B1;CXCL8;PPARG;OPRM1;PTGS2 GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;TRPV2;CHRNA7;CHRNB2;CACNA1G;GLRA1;TRPA1;TRPV1;VDAC1;TRPV4;CACNA1I;GLRB;TRPM8 GO:0006939| smooth muscle contraction HTR2A;CHRNB2 GO:0007165| signal transduction CXCL8;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNB2;CHRNA7;HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0050890| cognition CHRNB2;CHRNA7 GO:0007613| memory CHRNB2;CHRNA7;CNR1;HTR2A;PTGS2 GO:0007601| visual perception GLRB;CYP1B1;CHRNB2;GLRA1;CRYZ GO:0035094| response to nicotine CHRNA7;CNR1;CHRNB2 GO:0030593| neutrophil chemotaxis PLA2G1B;CXCL8 GO:0007626| locomotory behavior CHRNB2;SOD1;OPRM1 GO:0007612| learning CHRNB2;VDAC1;PTGS2 GO:0001508| regulation of action potential GLRA1;CHRNB2;CACNA1G GO:1905144| CHRNB2;CHRNA7 GO:0060079| regulation of excitatory postsynaptic membrane potential TRPV1;GLRB;CHRNB2;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0001666| response to hypoxia CAT;CHRNA7;CHRNB2;CYP1A1 GO:0071356| cellular response to tumor necrosis factor CXCL8;TRPV1 GO:0014059| regulation of dopamine secretion CHRNB2;HTR2A GO:0095500| CHRNB2;CHRNA7 GO:0034220| ion transmembrane transport TRPA1;GLRA1;CHRNB2;GLRB;TRPV1;GLRA3;CHRNA7 GO:0042220| response to cocaine CNR1;OPRM1;SMPD1;CHRNB2 GO:0045766| positive regulation of angiogenesis CHRNA7;CXCL8;CYP1B1 GO:0042391| regulation of membrane potential CACNA1H;GLRB;GLRA1;CACNA1G;CHRNB2 GO:0007605| sensory perception of sound SOD1;GPX1;CHRNB2 GO:0007186| G-protein coupled receptor signaling pathway CXCL8;GPR18;PPARG;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0045759| negative regulation of action potential CNR2;CNR1;CHRNB2 20979:[DB14011 DB13909] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13909|Bismuth subgallate ALB common genes common pathways GO:0098869| CAT;PTGS1;GPX1;PTGS2;ALB;GSR GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;PTGS2;HMGCR;ALB GO:0002576| platelet degranulation ALB;SOD1 GO:0001895| retina homeostasis ALB;SOD1 20980:[DB14011 DB03893] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways GO:0061844| PLA2G1B;GAPDH GO:0006915| apoptotic process VDAC1;GAPDH;GPX1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;GAPDH;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 20981:[DB14011 DB08262] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways GO:0010942| positive regulation of cell death HBB;HBA1;PTGS2 GO:0042542| response to hydrogen peroxide GPX1;CAT;SOD1;HBA1;TRPA1;HBB GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;HBB GO:0051291| protein heterooligomerization GLRB;GLRA1;HBB;HBA1 GO:0043312| neutrophil degranulation HBB;ALOX5;CAT GO:0042744| hydrogen peroxide catabolic process HBB;HBA1;CAT;GPX1 GO:0098869| CAT;PTGS1;GPX1;PTGS2;GSR;HBB;HBA1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1;HBB 20982:[DB14011 DB08745] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08745|4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;GPX1 20983:[DB14011 DB01922] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01922|Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam AMY2A;AMY2A common genes common pathways GO:0008152| metabolic process SMPD1;AMY2A;ACAT1 20984:[DB14011 DB05122] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways GO:0009611| response to wounding ITGB4;GPX1;CYP1A1 GO:0007155| cell adhesion CYP1B1;ITGB4;ITGA4;ITGB7 GO:0071345| cellular response to cytokine stimulus TRPV1;ITGA4 GO:0046718| entry of virus into host cell ITGB7;HTR2A GO:0048565| digestive tract development ITGB4;CYP1A1 20985:[DB14011 DB02585] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02585|4-(Hydroxymethyl)Benzamidine PRSS3 common genes common pathways GO:0043542| endothelial cell migration CYP1B1;PRSS3 GO:0043312| neutrophil degranulation ALOX5;CAT;PRSS3 GO:0009235| cobalamin metabolic process PRSS3;ABCC1 20986:[DB14011 DB04065] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;ADH1A;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;ADH1A;CYP1A1;CYP2C9;CRYZ;PTGS1;ALOX5;GPX1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1 20987:[DB14011 DB09075] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09075|Edoxaban F10;ABCB1 common genes common pathways GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCB1;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV1;ABCB1;CACNA1I;TRPV4;VDAC1;TRPV3;CACNA1H;TRPV2 GO:0006810| transport TRPV2;CACNA1I;ABCB1;TRPV1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 20988:[DB14011 DB04720] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04720|S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0048511| rhythmic process PPARG;CSNK2A1;AANAT GO:0006915| apoptotic process GPX1;CSNK2A1;VDAC1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;CSNK2A1;HMGCR;PTGS2 GO:0006355| regulation of transcription, DNA-dependent PPARG;CSNK2A1 GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;CSNK2A1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0006351| transcription, DNA-dependent CSNK2A1;PPARG GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CSNK2A1;PTGS2 20989:[DB14011 DB04002] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04002|4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide CA2 common genes common pathways GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0001822| kidney development CA2;CAT GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CA2;PPARG;CYP1A1;TRPA1 20990:[DB14011 DB07965] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07965|6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)-ethyl]-9H-purine-2-carbonitrile CTSK common genes common pathways GO:1903146| CTSK;VDAC1 GO:0045453| bone resorption GPR55;CTSK 20991:[DB14011 DB08689] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways GO:0009060| aerobic respiration SDHC;SDHB;CAT GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;SDHB;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SDHD;SOD1;SDHA;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A1;CYP2C9;CRYZ;SDHC GO:0022900| electron transport chain IDO1;GSR;SDHA;CYP1A2 GO:0007399| nervous system development GLRB;SMPD1;SDHA 20992:[DB14011 DB01112] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport ABCG2;TRPV1;CACNA1I;SLC15A1;ABCC1;TRPV2;SLC15A2 GO:0055085| transmembrane transport TRPA1;SLC15A1;CACNA1G;ABCC1;ABCG2;TRPM8;VDAC1;CACNA1I;TRPV4;TRPV1;SLC15A2;CACNA1H;TRPV3;TRPV2 GO:0006811| ion transport GLRA3;SLC15A2;TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;GLRA1;SLC15A1;CACNA1G;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1 20993:[DB14011 DB04453] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04453|4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose AMY2A;AMY2A common genes common pathways GO:0008152| metabolic process SMPD1;ACAT1;AMY2A 20994:[DB14011 DB05079] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05079|HY10275 HRH1;HTR2A common genes HTR2A common pathways GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;TRPV1;TRPA1 GO:0030431| sleep HTR2A;SLC29A1;CACNA1I GO:0045821| positive regulation of glycolysis HTR2A GO:0048148| behavioral response to cocaine HTR2A GO:0007208| activation of phospholipase C activity by serotonin receptor signaling pathway HTR2A GO:0001659| temperature homeostasis TRPV1;HTR2A;GPX1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain TRPA1;HTR2A GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;GLRA3;CACNA1G;GLRA1;VDAC1;GLRB GO:0016032| viral reproduction VDAC1;HTR2A GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;HRH1;ALOX15;IDO1;TRPV1 GO:0008542| visual learning HRH1;HMGCR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A GO:0050965| detection of temperature stimulus involved in sensory perception of pain TRPV1;HTR2A GO:0033674| positive regulation of kinase activity HTR2A GO:0046718| entry of virus into host cell HTR2A GO:0014832| urinary bladder smooth muscle contraction HTR2A;TRPV1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV1;TRPV4 GO:0007613| memory CHRNA7;HRH1;PTGS2;CNR1;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;HRH1;PTGS2 GO:0006939| smooth muscle contraction HTR2A GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A GO:0007165| signal transduction CHRNA7;HTR2A;CNR1;GPR12;HTR1A;GPR55;HRH1;OPRD1;CNR2;OPRM1;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0007610| behavior HTR1A;HTR2A GO:0043267| negative regulation of potassium ion transport HTR2A GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0046883| regulation of hormone secretion HTR1A;HTR2A GO:0014824| artery smooth muscle contraction HTR2A GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HRH1;OPRD1;OPRM1;HTR2A GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0050795| regulation of behavior HTR1A;HTR2A GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2 GO:0044380| protein localization to cytoskeleton HTR2A GO:0010513| positive regulation of phosphatidylinositol biosynthetic process HTR2A GO:0051967| negative regulation of synaptic transmission, glutamatergic HTR2A GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;HRH1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55 GO:0051209| release of sequestered calcium ion into cytosol HTR2A;TRPV1;TRPA1 GO:0007568| aging CAT;NAPEPLD;CNR1;SOD1;HTR2A;PTGS2;HMGCR;CYP1A1 GO:0007210| serotonin receptor signaling pathway HTR2A;HTR1A GO:0006874| cellular calcium ion homeostasis TRPM8;TRPV4;GPR12;HTR2A;CHRNA7 GO:0008219| cell death HTR2A GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;CHRNA7;HTR2A;GPR55;HMGCR;OPRM1 GO:0007202| activation of phospholipase C activity HTR2A;GPR55 GO:0014059| regulation of dopamine secretion HTR2A GO:0043406| positive regulation of MAP kinase activity HTR2A 20995:[DB14011 DB05403] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05403|CEP-1347 MAPK12 common genes common pathways GO:0007165| signal transduction GPR55;HTR1A;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;CHRNA7;PPARG;MAPK12;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0006351| transcription, DNA-dependent MAPK12;PPARG GO:0045445| myoblast differentiation HMGCR;MAPK12 GO:0010468| regulation of gene expression CYP1A2;MAPK12 GO:0045786| negative regulation of cell cycle PTGS2;MAPK12 GO:0006355| regulation of transcription, DNA-dependent MAPK12;PPARG GO:0007517| muscle organ development CACNA1H;MAPK12 20996:[DB14011 DB05961] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways GO:0045087| innate immune response SERPING1;PPARG GO:0043312| neutrophil degranulation SERPINA1;CAT;ALOX5 GO:0002576| platelet degranulation SERPING1;SERPINA1;SOD1 GO:0002376| immune system process IDO1;SERPING1 GO:0007568| aging CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT;CYP1A1;SERPING1 GO:0007283| spermatogenesis CNR1;SOD1;SERPINA5 20997:[DB14011 DB04982] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways GO:0006810| transport ABCC1;GRIA4;ABCG2;CACNA1I;TRPV1;GRIA3;TRPV2 GO:0034220| ion transmembrane transport GRIA3;GLRA3;GRIA2;CHRNA7;GRIA4;TRPA1;GLRA1;GLRB;TRPV1;GRIA1 GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;GRIA2;CHRNA7;OPRM1;GRIA3;GLRA3;GRIA1;TRPV1;GLRB;GRIA4;GLRA1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;GRIA1;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;GRIA2;CHRNA7 GO:0006811| ion transport CHRNA7;GRIA2;TRPV2;GLRA3;GRIA3;CACNA1H;TRPV3;TRPM8;GLRB;TRPV4;CACNA1I;VDAC1;TRPV1;GRIA1;GLRA1;TRPA1;GRIA4;CACNA1G GO:0060078| regulation of postsynaptic membrane potential GRIA1;CHRNA7 GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;GRIA2;CACNA1G;GLRA1;GLRB;VDAC1;GRIA1 20998:[DB14011 DB11386] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11386|Chlorobutanol KCNH2 common genes common pathways GO:0086091| CACNA1G;KCNH2 GO:0086010| CACNA1H;KCNH2;CACNA1G;CACNA1I GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;KCNH2;CACNA1H GO:0006811| ion transport VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;TRPV3;KCNH2;CACNA1H;GLRA3 GO:0042391| regulation of membrane potential KCNH2;CACNA1H;CACNA1G;GLRA1;GLRB GO:0055085| transmembrane transport TRPV2;KCNH2;CACNA1H;TRPV3;TRPV4;CACNA1I;VDAC1;TRPV1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 20999:[DB14011 DB06021] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06021|AV-412 EGFR;ERBB2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;PPARG;CYP1A1;TRPA1;EGFR GO:0008283| cell proliferation CYP1A1;EGFR;HTR1A;GPX1;ERBB2 GO:0045740| positive regulation of DNA replication PLA2G1B;EGFR GO:0048146| positive regulation of fibroblast proliferation EGFR;PLA2G1B GO:0071276| cellular response to cadmium ion SOD1;CYP1A2;EGFR GO:0032930| positive regulation of superoxide anion generation EGFR;SOD1 GO:0046718| entry of virus into host cell EGFR;HTR2A GO:0050729| positive regulation of inflammatory response EGFR;TRPV4 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2;HTR2A GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;ERBB2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1;EGFR GO:0007165| signal transduction ERBB2;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;EGFR;SMPD1;PPARG;GPR18 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ERBB2;EGFR GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;EGFR;ERBB2 GO:0006970| response to osmotic stress EGFR;TRPV4 GO:0051592| response to calcium ion AANAT;EGFR GO:0006351| transcription, DNA-dependent ERBB2;PPARG GO:0001889| liver development ACAT1;CYP1A1;EGFR GO:0007166| cell surface receptor linked signaling pathway EGFR;TRPV1;TRPA1;ERBB2 GO:0035556| intracellular signal transduction PLA2G1B;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0007507| heart development PPARG;ERBB2 GO:0001503| ossification ALOX15;EGFR GO:0007399| nervous system development ERBB2;SMPD1;GLRB GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4;EGFR GO:0007202| activation of phospholipase C activity HTR2A;GPR55;EGFR GO:0010628| positive regulation of gene expression TRPV4;ERBB2 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity EGFR;HTR2A;ERBB2 GO:0032355| response to estradiol stimulus EGFR;CAT;CYP1A2;PTGS2 GO:0071363| cellular response to growth factor stimulus TRPV1;EGFR;OPRD1;CAT;ERBB2 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;EGFR;OPRM1;PTGS2 GO:0006979| response to oxidative stress EGFR;CAT;PTGS1;GPX1;SOD1;PTGS2 GO:0033993| response to lipid PPARG;EGFR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;PPARG GO:0006355| regulation of transcription, DNA-dependent ERBB2;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;HMGCR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;ERBB2;EGFR GO:0007611| learning or memory CNR1;CHRNA7;EGFR GO:0042060| wound healing ERBB2;OPRM1;EGFR;ALOX15 GO:0042127| regulation of cell proliferation EGFR;PTGS1;PTGS2 GO:0007623| circadian rhythm AANAT;EGFR GO:0030324| lung development EGFR;CYP1A2 GO:0071230| cellular response to amino acid stimulus EGFR;GLRA1 GO:0043066| negative regulation of apoptotic process EGFR;CAT;GPX1;SOD1;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGFR;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;EGFR 21000:[DB14011 DB04869] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04869|Olcegepant CALCA;CALCRL common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;CALCRL;CALCA;GPR18;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;GPR18;CALCA GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR2;OPRM1;OPRD1;CNR1;CALCRL GO:0045671| negative regulation of osteoclast differentiation GPR55;CALCA GO:0045087| innate immune response CALCA;PPARG GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7;CALCRL GO:0043542| endothelial cell migration CALCA;CYP1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR;CALCRL GO:0045986| negative regulation of smooth muscle contraction CALCRL;PTGS2 GO:0050728| negative regulation of inflammatory response CALCRL;CNR2 GO:0019731| antibacterial humoral response CALCA;PLA2G1B GO:0050830| defense response to Gram-positive bacterium CALCA;PLA2G1B GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;CALCRL;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;CALCA GO:0061844| CALCA;PLA2G1B GO:0007507| heart development PPARG;CALCRL GO:0007166| cell surface receptor linked signaling pathway TRPV1;CALCRL;TRPA1 GO:0001525| angiogenesis CALCRL;CYP1B1;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;CALCA GO:0006816| calcium ion transport TRPV3;CACNA1H;CHRNA7;TRPV2;TRPA1;CALCRL;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I 21001:[DB14011 DB13951] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes CYP17A1 common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ESR1;AR GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HMGCR;PTGS2;HTR2A;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;AR;ESR1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;ESR1;OPRD1;OPRM1 GO:0008203| cholesterol metabolic process CAT;CYP11A1;HMGCR GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1;NR3C2;PPARG GO:0008210| estrogen metabolic process CYP1B1;HSD17B1 GO:0006694| steroid biosynthetic process HMGCR;CYP11A1;HSD17B1;CYP19A1;CYP17A1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP19A1;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;HMGCR;CYP1A2;PTGS2;CYP3A7;CYP11A1;SOD1;CYP3A4;HSD17B1;ALOX5;PTGS1;GPX1;CAT GO:0006355| regulation of transcription, DNA-dependent ESR1;AR;PPARG;NR3C2 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2;ABCB1 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR;ESR1 GO:0022900| electron transport chain IDO1;GSR;CYP19A1;CYP1A2 GO:0006704| glucocorticoid biosynthetic process CYP17A1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;ESR1;OPRM1;PTGS2 GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport TRPV2;AR;TRPV1;CACNA1I;ABCB1;ABCG2;ABCC1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP1A1;CYP2C9;CYP11A1;CYP3A4;HMGCR;CYP3A7;CYP1A2 GO:0042446| hormone biosynthetic process CYP17A1 GO:0007283| spermatogenesis SOD1;CNR1;AR GO:0042359| vitamin D metabolic process CYP3A4;CYP11A1;CYP1A1 GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0055085| transmembrane transport ABCG2;TRPM8;ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP11A1;CYP3A4;NAPEPLD;HSD17B1;NAAA;PTGS1;GPX1;PPARG;CYP2C9;TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0016125| sterol metabolic process CYP19A1;CYP1B1;CYP17A1;CYP11A1 GO:0006351| transcription, DNA-dependent AR;ESR1;NR3C2;PPARG GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;PPARG;NR3C2 GO:0006357| regulation of transcription from RNA polymerase II promoter AR;ESR1;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042448| progesterone metabolic process CYP17A1 GO:0008209| androgen metabolic process CYP19A1;ESR1;CYP3A4 GO:0010629| negative regulation of gene expression OPRD1;ESR1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;ESR1;HTR2A;GPR12;CNR1;AR;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;NR3C2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV1;TRPV4 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0043627| response to estrogen stimulus PPARG;ESR1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;PTGS2;OPRM1 GO:0048146| positive regulation of fibroblast proliferation ESR1;PLA2G1B GO:0007548| sex differentiation AR;CYP17A1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006702| androgen biosynthetic process CYP17A1 GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 21002:[DB14011 DB02288] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02288|CRA_9334 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 21003:[DB14011 DB09161] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes ABCC1 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0099133| ABCC1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCB1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT GO:0006691| leukotriene metabolic process ABCC1;ALOX15;ALOX5 GO:0060326| cell chemotaxis ABCC1 GO:0006810| transport ABCC1;ABCG2;CACNA1I;ABCB1;TRPV1;TRPV2 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;TRPV4;ABCB1;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2 21004:[DB14011 DB00141] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways GO:0051260| protein homooligomerization GLRA1;B4GALT1;GLRA3;ACAT1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;B4GALT1 GO:0042060| wound healing ALOX15;B4GALT1;OPRM1 GO:0007626| locomotory behavior B4GALT2;SOD1;OPRM1 GO:0007155| cell adhesion CYP1B1;B4GALT1 GO:0043312| neutrophil degranulation ALOX5;CAT;B4GALT1 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7;B4GALT2 GO:0060055| angiogenesis involved in wound healing GPX1;B4GALT1 GO:0007420| brain development ACAT1;B4GALT2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;PPARG;B4GALT1;CYP1B1 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG;RENBP GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;B4GALT1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0008152| metabolic process ACAT1;SMPD1;NAGLU GO:0007399| nervous system development SMPD1;NAGLU;GLRB GO:0008542| visual learning B4GALT2;HMGCR 21005:[DB14011 DB03904] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways GO:0016525| negative regulation of angiogenesis PPARG;CTNNB1 GO:0033189| response to vitamin A CYP1A1;PPARG;ARG1;CAT GO:0010042| response to manganese ion PTGS2;ARG1 GO:0050808| synapse organization CTNNB1;CHRNA7 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CTNNB1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CTNNB1;CAT;ARG1;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG;CTNNB1 GO:0043312| neutrophil degranulation ALOX5;ARG1;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;CTNNB1 GO:0007155| cell adhesion CYP1B1;CTNNB1 GO:0045087| innate immune response ARG1;PPARG GO:0001822| kidney development CTNNB1;CAT;CA2 GO:0070207| protein homotrimerization TRPM8;ARG1 GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;PTGS2;HMGCR;CTNNB1;CHRNA7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CTNNB1;PLA2G1B;PPARG GO:0030324| lung development ARG1;CYP1A2;CTNNB1 GO:0060135| maternal process involved in female pregnancy ARG1;CNR1 GO:0033197| response to vitamin E CAT;ARG1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;CTNNB1 GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;ARG1;CNR2;PTGS2;CYP1A2;OPRM1;CNR1 GO:0010033| response to organic substance CA2;PPARG;CYP1A1;TRPA1;PTGS2;CYP1A2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;CTNNB1 GO:0042130| negative regulation of T cell proliferation IDO1;ARG1 GO:0010628| positive regulation of gene expression CTNNB1;TRPV4 GO:0045671| negative regulation of osteoclast differentiation CTNNB1;GPR55 GO:0055085| transmembrane transport TRPV2;SLC14A2;CACNA1H;TRPV3;TRPV1;SLC14A1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 GO:0043200| response to amino acid stimulus GLRB;GLRA3;ARG1 GO:0046686| response to cadmium ion ARG1;CAT GO:0002376| immune system process IDO1;ARG1 GO:0048538| thymus development SOD1;CTNNB1 GO:0007568| aging ARG1;CAT;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CYP1A1 GO:0010468| regulation of gene expression CTNNB1;CYP1A2 GO:0009611| response to wounding ARG1;GPX1;CYP1A1 GO:0032355| response to estradiol stimulus CAT;CTNNB1;PTGS2;CYP1A2 GO:0071363| cellular response to growth factor stimulus TRPV1;CTNNB1;OPRD1;CAT GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH TRPV1;CA2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;CTNNB1 GO:0030217| T cell differentiation CTNNB1;GPR18 GO:0007565| female pregnancy IDO1;ARG1 GO:0009635| response to herbicide CYP1A1;ARG1 GO:0007268| synaptic transmission GLRA1;CACNA1G;GLRB;VDAC1;HTR2A;GLRA3;OPRD1;CTNNB1;OPRM1 GO:0010629| negative regulation of gene expression OPRD1;CTNNB1 GO:0007507| heart development PPARG;CTNNB1 GO:0007399| nervous system development CTNNB1;SMPD1;GLRB GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;CYP1B1;TRPV1;IDO1;CTNNB1;PTGS2;SOD1;CNR1 GO:0048678| response to axon injury ARG1;SOD1 GO:0006351| transcription, DNA-dependent PPARG;CTNNB1 GO:0001889| liver development CYP1A1;ACAT1;ARG1 GO:0048469| cell maturation CTNNB1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;CTNNB1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CTNNB1;PPARG;CYP1B1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway ARG1;PPARG GO:0043627| response to estrogen stimulus CA2;PPARG GO:0070301| cellular response to hydrogen peroxide ARG1;CYP1B1 GO:0010043| response to zinc ion AANAT;ARG1;CA2 GO:0048643| positive regulation of skeletal muscle tissue development CTNNB1;HMGCR GO:0010269| response to selenium ion ARG1;GPX1 GO:0008283| cell proliferation GPX1;CTNNB1;HTR1A;CYP1A1 GO:0045453| bone resorption GPR55;CTNNB1 GO:0043434| response to peptide hormone stimulus ARG1;TRPV1 21006:[DB14011 DB07177] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0006693| prostaglandin metabolic process PTGR2;PTGS1;PTGR1;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;PTGR1;ALOX5;GPX1;PTGS1;CAT;PTGR2;CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6 GO:0006691| leukotriene metabolic process ALOX5;PTGR1;ALOX15;ABCC1 21007:[DB14011 DB03793] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0098869| PTGS2;PRDX5;PTGS1;GPX1;CAT;GSR GO:0006979| response to oxidative stress CAT;PTGS1;GPX1;PRDX5;SOD1;PTGS2 GO:0042593| glucose homeostasis TRPV4;PPARG;SLC16A1;CNR1 GO:0006810| transport TRPV2;SLC15A1;ABCC1;ABCG2;CACNA1I;TRPV1 GO:0006915| apoptotic process PRDX5;GPX1;VDAC1 GO:0042744| hydrogen peroxide catabolic process GPX1;CAT;PRDX5 GO:0055085| transmembrane transport TRPV2;SLC16A1;CACNA1H;TRPV3;SLC22A8;TRPV1;VDAC1;TRPV4;CACNA1I;ABCG2;TRPM8;SLCO2B1;CACNA1G;ABCC1;SLC15A1;TRPA1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;PRDX5;SOD1 GO:0034599| cellular response to oxidative stress PRDX5;SOD1;CAT;GPX1;GSR GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1;SLC16A1 GO:0032094| response to food SLC16A1;OPRM1;CYP1A1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;PRDX5;SOD1;CYP3A4;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;DAO;CRYZ;CYP2C9;CYP1A1 GO:0045454| cell redox homeostasis GSR;PRDX5;GPX1 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0098656| SLC22A8;VDAC1 GO:0009636| response to toxin SLC22A8;CAT;GPX1;CYP1A1;CYP1B1 GO:0006811| ion transport SLC22A8;GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;SLC15A1;TRPA1;GLRA1;CACNA1G;SLCO2B1;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I GO:0006629| lipid metabolic process SLC16A1;PTGS1;NAAA;GPX1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0006954| inflammatory response IDO1;ALOX15;TRPV1;ALOX5;PTGS1;PRDX5;CNR2;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PRDX5;PTGS2 21008:[DB14011 DB02925] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02925|Piretanide SLC12A1 common genes common pathways GO:0006810| transport SLC12A1;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;VDAC1;CACNA1I;TRPV4;TRPV1;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2;SLC12A1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;SLC12A1;TRPA1;GLRA1;GLRB;TRPV1 GO:0006811| ion transport TRPV2;SLC12A1;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;CACNA1G;GLRA1;TRPA1 GO:1902476| GLRA3;SLC12A1;GLRA1;GLRB 21009:[DB14011 DB08232] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;F7 GO:0045766| positive regulation of angiogenesis CYP1B1;F3;CHRNA7 GO:0031100| organ regeneration F7;PPARG GO:0032355| response to estradiol stimulus F7;PTGS2;CYP1A2;CAT GO:0051897| positive regulation of protein kinase B signaling cascade F7;F3;GPX1 GO:0007623| circadian rhythm AANAT;F7 GO:0043627| response to estrogen stimulus F7;PPARG GO:0006919| activation of caspase activity PPARG;F3 GO:0014070| response to organic cyclic compound F7;TRPA1;PPARG;CYP1A1;ACAT1;AANAT;CYP1A2;PTGS2 GO:0009725| response to hormone stimulus F7;ACAT1 GO:0031667| response to nutrient levels SOD1;F7 21010:[DB14011 DB13501] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13501|Bendazac PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;ACAT1;AANAT GO:0033280| response to vitamin D PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CYP1B1;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0019233| sensory perception of pain OPRM1;PTGS2;CNR2;OPRD1;CNR1;HTR2A;TRPV1;TRPA1 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;PPARG;CYP2C9;NAAA;GPX1;PTGS1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:1990776| PTGS2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2C19;CYP2D6 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;ALOX15;IDO1;TRPV1 GO:0010942| positive regulation of cell death PTGS2 GO:0007568| aging CAT;PTGS2;HMGCR;NAPEPLD;HTR2A;SOD1;CNR1;CYP1A1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:1902219| PTGS2 GO:0098869| PTGS2;PTGS1;GPX1;CAT;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;PTGS1;GPX1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;PPARG;CYP1A1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning VDAC1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;PTGS2;CNR2;CNR1;CYP1A1;IDO1 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process HMGCR;CYP1A2;CYP3A7;PTGS2;SOD1;CYP3A4;PTGS1;ALOX5;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway PTGS2;ALOX5;GPX1;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 21011:[DB14011 DB02731] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways GO:0007420| brain development ACAT1;OXCT1 GO:0009725| response to hormone stimulus OXCT1;ACAT1 GO:0046952| ketone body catabolic process ACAT1;OXCT1 GO:0007584| response to nutrient CNR1;HMGCR;OXCT1;PPARG GO:0014823| response to activity CAT;OXCT1 GO:0060612| adipose tissue development OXCT1;ACAT1 GO:0045471| response to ethanol OXCT1;CAT;OPRM1;HMGCR;SOD1;CNR1 GO:0007507| heart development PPARG;OXCT1 GO:0008152| metabolic process ACAT1;OXCT1;SMPD1 GO:0042594| response to starvation ACAT1;OXCT1;PPARG GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;OXCT1;PTGS2;CYP1A2;SOD1;HTR2A;CAT 21012:[DB14011 DB07984] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes PTGS1 common pathways GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;ALOX5;PTGS1;PTGS2;CNR2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP2D6;CYP2C19;CYP3A5;CYP1B1;CYP2C9 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process ALOX15;DAGLA;CYP2D6;PLA2G1B;TRPV1;CYP2C9;PPARG;NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;CYP1A2;PTGS2;HMGCR GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;SOD1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;PTGS1;ALOX5;GPX1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0098869| GSR;CAT;GPX1;PTGS1;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 21013:[DB14011 DB13892] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13892|Crotalus atrox antivenin PLA2G10;CYP4A11 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP4A11;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:0006654| phosphatidic acid biosynthetic process PLA2G10;PLA2G1B GO:0036151| PLA2G1B;PLA2G10 GO:0019369| arachidonic acid metabolic process DAGLA;CYP2D6;ALOX15;CYP1B1;PLA2G10;CYP4A11;FAAH GO:0006631| fatty acid metabolic process PTGS1;CYP4A11;PTGS2;ALOX15 GO:0006691| leukotriene metabolic process ABCC1;ALOX15;CYP4A11;ALOX5 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;CYP4A11;HMGCR;CYP3A4;SOD1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1A1;CYP2C9;CRYZ GO:0036152| PLA2G10;PLA2G1B GO:0006644| phospholipid metabolic process PLA2G10;NAPEPLD;PLA2G1B GO:0016042| lipid catabolic process DAGLA;PLA2G1B;NAPEPLD;PLA2G10 GO:0006629| lipid metabolic process CYP1A2;PLA2G10;PTGS2;HMGCR;CYP3A4;NAPEPLD;NAAA;GPX1;PTGS1;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6 GO:0036148| PLA2G10;PLA2G1B GO:0036149| PLA2G10;PLA2G1B GO:0050482| arachidonic acid secretion PLA2G1B;PLA2G10 GO:0097267| CYP1A2;CYP4A11;CYP1A1;CYP2C9;CYP1B1;CYP2C19 GO:0019216| regulation of lipid metabolic process CYP4A11;HMGCR;CNR1;CYP1A1;PPARG GO:0036150| PLA2G10;PLA2G1B 21014:[DB14011 DB06480] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes CYP3A4 common pathways GO:0006629| lipid metabolic process HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;PPARG;CYP2C9;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP3A4;CYP1A2 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR4;HTR2A;GLRA3;VDAC1;GLRB;CACNA1G;GLRA1 GO:0007165| signal transduction PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B;HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;HTR4;OPRM1;OPRD1;CHRNA7 GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2D6;CYP3A4;CYP1A2 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0001895| retina homeostasis SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0042493| response to drug ABCG2;ABCB1;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0098869| GSR;ALB;CAT;PTGS1;GPX1;PTGS2 GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCB1;ABCG2;ABCC1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;HTR4;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1 GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;OPRD1;HTR4;CNR2;OPRM1 GO:0009822| alkaloid catabolic process CYP3A5;CYP2D6;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0036378| CYP3A4 GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;ABCB1;TRPV4;CACNA1I;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP1A1 21015:[DB14011 DB04216] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04216|Quercetin HCK;PIK3CG;UGT3A1;ATP5B;PIM1;HIBCH;fabZ;STK17B;ESR1;ESR2;NQO2;AHR;CYP1B1;ACTB;CSNK2A1;CSNK2B;EIF3F;HSP90AA1;HSPA2;RUVBL2;SF3B3;UBA1;SHBG;CBR1;CEBPB;NR1I2;CYP2C8;ALB;ABCC1;ABCC2;SLC16A7;SLCO2B1;ABCB1;SLC16A1;ABCG2;SLCO1B1 common genes ABCG2;CYP1B1;ABCC1 common pathways GO:0032870| cellular response to hormone stimulus ABCC2;CACNA1H GO:0070989| oxidative demethylation CYP2C9;CYP3A5;CYP2C8;CYP2D6;CYP3A4;CYP1A2 GO:0014065| phosphatidylinositol 3-kinase cascade HTR2A;PIK3CG GO:0034644| cellular response to UV RUVBL2;PTGS2 GO:0007165| signal transduction ESR1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;CSNK2A1;OPRD1;CHRNA7;HSP90AA1;PPARG;NR1I2;GPR18;SMPD1;ESR2;CACNA1I;PLA2G1B;CSNK2B GO:0097267| CYP2C8;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0001649| osteoblast differentiation ATP5B;CAT GO:0042908| xenobiotic transport NR1I2;ABCC1;ABCG2;ABCB1 GO:0007601| visual perception GLRA1;CRYZ;GLRB;CYP1B1 GO:0050796| regulation of insulin secretion CNR1;SLC16A1 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;TRPV4;PIK3CG;ESR1;HTR2A;OPRM1 GO:0007613| memory CHRNA7;HTR2A;CNR1;PTGS2;CEBPB GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0030336| negative regulation of cell migration CYP1B1 GO:0045600| positive regulation of fat cell differentiation CEBPB;PPARG;HTR2A GO:0034976| response to endoplasmic reticulum stress CEBPB;ALOX15 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;CSNK2B GO:0046466| membrane lipid catabolic process CYP1B1 GO:0008285| negative regulation of cell proliferation CSNK2B;CYP1B1;PPARG;PTGS2;OPRM1 GO:0070301| cellular response to hydrogen peroxide CYP1B1 GO:0043627| response to estrogen stimulus ESR1;ABCC2;PPARG GO:0009636| response to toxin CAT;GPX1;CYP1A1;AHR;CYP1B1 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0008283| cell proliferation GPX1;PIM1;HTR1A;CYP1A1 GO:0006811| ion transport TRPV1;CACNA1I;TRPV4;GLRB;VDAC1;SLCO2B1;TRPM8;ATP5B;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;SLCO1B1;GLRA3 GO:0006809| nitric oxide biosynthetic process CYP1B1 GO:0001895| retina homeostasis ALB;ACTB;SOD1 GO:0002930| CYP1B1 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2;ABCG2 GO:0009409| response to cold TRPM8;TRPA1;PPARG;HSP90AA1;HSPA2 GO:0016125| sterol metabolic process CYP1B1;CYP17A1 GO:0035556| intracellular signal transduction STK17B;PLA2G1B GO:0008152| metabolic process UGT3A1;SMPD1;ACAT1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP1B1;NR1I2;CYP2C9;AHR;NQO2;PTGS1;CYP3A4;CYP1A2;CYP3A7 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;CYP1B1;TRPV1;IDO1;SMPD1;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2;HCK GO:0042572| retinol metabolic process CYP1B1 GO:0006629| lipid metabolic process ATP5B;PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;PTGS2;CYP1A2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1;SLC16A1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:2000377| regulation of reactive oxygen species metabolic process CYP1B1 GO:0006357| regulation of transcription from RNA polymerase II promoter AHR;PPARG;ESR1 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;CEBPB;AHR;ESR2;RUVBL2;ESR1;CSNK2A1 GO:0001889| liver development ACAT1;CEBPB;CYP1A1 GO:0043401| steroid hormone mediated signaling pathway ESR1;ESR2;PPARG;NR1I2 GO:0050873| brown fat cell differentiation CEBPB;PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1;ATP5B;PIK3CG GO:0006955| immune response CEBPB;CNR2;OPRD1 GO:0016032| viral reproduction HTR2A;HCK;VDAC1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;PPARG;ESR1 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;HCK;PIK3CG;CEBPB;ALOX15;IDO1;TRPV1 GO:0009408| response to heat ABCC2;TRPV1;HSP90AA1;TRPV2;SOD1;HSPA2;TRPV3 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0045859| regulation of protein kinase activity CSNK2B;SOD1 GO:0071603| endothelial cell-cell adhesion CYP1B1 GO:0043524| negative regulation of neuron apoptosis CEBPB;SOD1 GO:0071320| cellular response to cAMP AANAT;PIK3CG GO:0019371| cyclooxygenase pathway PTGS2;CBR1;PTGS1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C8;NR1I2;CYP2C9 GO:0007565| female pregnancy IDO1;ABCC2 GO:0001934| positive regulation of protein phosphorylation HSPA2;CHRNA7 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;CSNK2A1;PTGS2 GO:0046415| urate metabolic process ABCG2 GO:0008631| induction of apoptosis by oxidative stress CYP1B1;GPX1 GO:0008209| androgen metabolic process ESR1;CYP3A4 GO:0042574| retinal metabolic process CYP1B1 GO:0098869| PTGS2;GPX1;PTGS1;CAT;ALB;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;ESR1;TRPV1;HSP90AA1 GO:0006979| response to oxidative stress ABCC2;SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0042593| glucose homeostasis CNR1;SLC16A1;PPARG;TRPV4 GO:0002376| immune system process HCK;IDO1;PIK3CG GO:0043085| positive regulation of catalytic activity SOD1;PIK3CG GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C8;CYP2C19;CYP3A4;CYP1A2;CBR1 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP1A1;NR1I2 GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;PIK3CG;PPARG;GPR18 GO:0009235| cobalamin metabolic process ABCC1 GO:0060850| regulation of transcription involved in cell fate commitment PPARG;CEBPB GO:0032355| response to estradiol stimulus ESR1;PTGS2;CYP1A2;CAT GO:0048514| blood vessel morphogenesis CYP1B1 GO:0006810| transport TRPV2;TRPV1;CACNA1I;ABCB1;ABCG2;ABCC2;ABCC1 GO:0010468| regulation of gene expression AHR;CYP1A2 GO:0007283| spermatogenesis SOD1;CNR1;HSPA2 GO:0010628| positive regulation of gene expression TRPV4;NR1I2 GO:0042130| negative regulation of T cell proliferation IDO1;CEBPB GO:0045892| negative regulation of transcription, DNA-dependent AHR;CEBPB;NR1I2;PPARG GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0048511| rhythmic process PPARG;AHR;AANAT;CSNK2A1 GO:0043406| positive regulation of MAP kinase activity PIK3CG;HTR2A GO:0002933| CYP3A5;CYP2C8;CYP1A1;CYP3A4;CYP3A7 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7 GO:0001541| ovarian follicle development SOD1;CEBPB GO:0030855| epithelial cell differentiation VDAC1;PPARG;CBR1 GO:0006915| apoptotic process STK17B;AHR;VDAC1;PIM1;CSNK2A1;GPX1 GO:0055085| transmembrane transport SLCO1B1;SLC16A7;CACNA1H;TRPV3;SLC16A1;TRPV2;TRPA1;CACNA1G;ABCC1;ABCG2;ABCC2;TRPM8;SLCO2B1;VDAC1;ABCB1;CACNA1I;TRPV4;TRPV1 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2;HMGCR;SOD1;GPX1;HCK;CAT;ALB GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;NR1I2;CEBPB;AHR;ESR2;PLA2G1B;RUVBL2;ESR1 GO:0008284| positive regulation of cell proliferation HCK;CHRNA7;PTGS2;HMGCR;CSNK2A1;HTR1A;HTR2A GO:0002576| platelet degranulation ALB;SOD1 GO:0046677| response to antibiotic SOD1;HSP90AA1;CYP1A1 GO:0043312| neutrophil degranulation HSP90AA1;CSNK2B;CAT;ALOX5 GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;CEBPB;PPARG;TRPV4;TRPV1;ESR2 GO:0007155| cell adhesion CYP1B1;HCK GO:0045087| innate immune response HCK;PPARG;PIK3CG GO:0009410| response to xenobiotic stimulus GPX1;AHR GO:0030838| positive regulation of actin filament polymerization HCK;ALOX15 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0032496| response to lipopolysaccharide CYP1A1;CEBPB;ABCC2;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0043542| endothelial cell migration CYP1B1 GO:0061304| retinal blood vessel morphogenesis CYP1B1 GO:0071230| cellular response to amino acid stimulus CEBPB;GLRA1 GO:0033344| cholesterol efflux ABCG2 GO:0030199| collagen fibril organization CYP1B1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0060326| cell chemotaxis ABCC1 GO:0009083| branched chain family amino acid catabolic process ACAT1;HIBCH GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CG;GPX1 GO:0033629| negative regulation of cell adhesion mediated by integrin CYP1B1 GO:0061298| retina vasculature development in camera-type eye CYP1B1 GO:0015886| heme transport ABCG2 GO:0008210| estrogen metabolic process CYP1B1 GO:0006367| transcription initiation from RNA polymerase II promoter NR1I2;PPARG;ESR2;ESR1 GO:0099133| ABCC2;ABCC1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR;NQO2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;ESR2;NR1I2;PPARG;AHR;CEBPB GO:0032094| response to food CYP1A1;OPRM1;SLC16A1 GO:0071407| cellular response to organic cyclic compound SLC16A1;CEBPB;CYP1A1;CYP1B1 GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0030593| neutrophil chemotaxis PLA2G1B;PIK3CG GO:0016236| macroautophagy CSNK2B;VDAC1;CSNK2A1 GO:0045444| fat cell differentiation CEBPB;GPX1 GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;ESR1;RUVBL2;ESR2;AHR;CEBPB;NR1I2;PPARG GO:0042493| response to drug CAT;CYP1A2;PTGS2;SOD1;HTR2A;ABCB1;ABCG2;ABCC2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;CBR1;ALOX5;PTGS1;GPX1;CYP1A1;CYP2C9;CRYZ;NQO2;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;CYP2C8;IDO1;GSR;CYP1B1 GO:0046427| positive regulation of JAK-STAT cascade CYP1B1 21016:[DB14011 DB07983] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes PTGS1 common pathways GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP1A1;CYP2C9;PTGS1;ALOX5;GPX1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0098869| PTGS2;GPX1;PTGS1;CAT;GSR GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;TRPV1;IDO1;ALOX15 GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;PPARG;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP3A7;CYP1A2;PTGS1;CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP1B1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;SOD1;PTGS2;PPARG GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 21017:[DB14011 DB07769] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0006810| transport TRPV2;AR;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0010468| regulation of gene expression CYP1A2;AR GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV1;TRPV4;PPARG;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation AR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045893| positive regulation of transcription, DNA-dependent AR;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;AR GO:0007165| signal transduction CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1;CHRNA7;AR;HTR2A;CNR1;GPR12;HTR1A;GPR55;OPRD1;CNR2;OPRM1 GO:0007548| sex differentiation AR;CYP17A1 GO:0008283| cell proliferation CYP1A1;HTR1A;GPX1;AR GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;AR;OPRM1;PTGS2 GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AR GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B 21018:[DB14011 DB01250] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01250|Olsalazine TPMT;IFNG common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;IFNG GO:0010629| negative regulation of gene expression OPRD1;IFNG GO:0006955| immune response IFNG;OPRD1;CNR2 GO:0000060| protein import into nucleus, translocation OPRD1;IFNG GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;IFNG GO:0006139| nucleobase-containing compound metabolic process TPMT;SLC29A1 GO:0050796| regulation of insulin secretion IFNG;CNR1 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG;IFNG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG;IFNG GO:0008284| positive regulation of cell proliferation CHRNA7;IFNG;HTR2A;HTR1A;HMGCR;PTGS2 GO:0009615| response to virus CYP1A1;IFNG GO:0035722| interleukin-12-mediated signaling pathway IFNG;SOD1 GO:0032259| methylation TPMT;CYP1A2 GO:0006915| apoptotic process VDAC1;GPX1;IFNG GO:0045892| negative regulation of transcription, DNA-dependent IFNG;PPARG GO:0010628| positive regulation of gene expression TRPV4;IFNG GO:0032735| positive regulation of interleukin-12 production IFNG;IDO1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;IFNG 21019:[DB14011 DB00881] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0060047| heart contraction SOD1;GPX1;ACE GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0006811| ion transport SLC22A8;GLRA3;SLC15A2;CACNA1H;TRPV3;CHRNA7;TRPV2;SLC15A1;GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1 GO:0009636| response to toxin CAT;GPX1;SLC22A8;CYP1B1;CYP1A1 GO:0098656| SLC22A8;VDAC1 GO:0008217| regulation of blood pressure PTGS1;ACE;PTGS2;SOD1;PPARG GO:0006810| transport SLC15A2;TRPV2;ABCC1;SLC15A1;TRPV1;CACNA1I;ABCG2 GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLC22A8;SLC15A2;TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;SLC15A1;TRPA1 GO:0007283| spermatogenesis CNR1;SOD1;ACE GO:0001822| kidney development CAT;ACE 21020:[DB14011 DB07454] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;CAT;PLA2G1B GO:0006357| regulation of transcription from RNA polymerase II promoter AR;PPARG GO:0043401| steroid hormone mediated signaling pathway AR;PPARG GO:0006351| transcription, DNA-dependent PPARG;AR GO:0008283| cell proliferation AR;GPX1;HTR1A;CYP1A1 GO:0007548| sex differentiation CYP17A1;AR GO:0008285| negative regulation of cell proliferation AR;PTGS2;OPRM1;CYP1B1;PPARG GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;AR;CHRNA7 GO:0006355| regulation of transcription, DNA-dependent AR;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;AR GO:0006367| transcription initiation from RNA polymerase II promoter AR;PPARG GO:0008284| positive regulation of cell proliferation CHRNA7;AR;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PPARG;PLA2G1B GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;AR GO:0010628| positive regulation of gene expression AR;TRPV4 GO:0007283| spermatogenesis AR;SOD1;CNR1 GO:0010468| regulation of gene expression CYP1A2;AR GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;AR;TRPV2 21021:[DB14011 DB08489] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08489|N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YL)-SUCCINAMIDE MMP7 common genes common pathways GO:0060135| maternal process involved in female pregnancy MMP7;CNR1 GO:0007568| aging PTGS2;HMGCR;NAPEPLD;CNR1;HTR2A;SOD1;CAT;MMP7;CYP1A1 GO:0031667| response to nutrient levels SOD1;MMP7 GO:0071260| cellular response to mechanical stimulus MMP7;PTGS2 GO:0044849| OPRM1;MMP7 21022:[DB14011 DB00170] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes CYP1A2;CYP1A1 common pathways GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0043200| response to amino acid stimulus GLRA3;MTHFR;GLRB GO:0002933| CYP3A5;CYP1A1;CYP3A4;CYP3A7 GO:0071615| oxidative deethylation CYP1A2 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0001666| response to hypoxia F7;CYP1A1;CHRNA7;CAT;MTHFR GO:0010193| response to ozone CAT;CYP2E1 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;PPARG;CYP1A1;TRPA1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2;F7;NQO1 GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0007186| G-protein coupled receptor signaling pathway GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1;PPARG;GPR18;F2 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP2A6;CYP2E1;CYP3A4 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0007568| aging NQO1;CYP1A1;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0031100| organ regeneration PPARG;F7 GO:0006979| response to oxidative stress NQO1;PTGS1;GPX1;CAT;PTGS2;SOD1 GO:0010041| response to iron(III) ion CYP1A1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6;CYP1A2;VKORC1;CYP2C19;CYP2D6;CYP1A1;CYP2C9;AOX1 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;MTHFR;CYP2E1;HTR2A;SOD1;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0046685| response to arsenic-containing substance CYP1A1 GO:0032094| response to food OPRM1;CYP1A1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1 GO:0022900| electron transport chain XDH;CYP1A2;AOX1;NQO2;IDO1;GSR GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;VKORC1L1;SOD1;CYP2A6;CYP2E1;CYP3A4;HMGCR;MTHFR;XDH;CYP1A2;PTGS2;VKORC1;CYP3A7;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;AOX1;CYP2C9;CYP1A1;NQO1;NQO2 GO:0009804| coumarin metabolic process CYP2A6;CYP1A1;CYP2D6 GO:0006801| superoxide metabolic process NQO1;SOD1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0050728| negative regulation of inflammatory response PROC;CNR2 GO:0010243| response to organic nitrogen TRPV1;PTGS2;CYP2E1 GO:0009308| amine metabolic process CYP1A1 GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0051897| positive regulation of protein kinase B signaling cascade F7;F10;GPX1 GO:0007623| circadian rhythm F7;AANAT GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2;OPRM1;CYP1A2;CYP1A1;IDO1 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0034599| cellular response to oxidative stress CAT;GPX1;VKORC1L1;SOD1;GSR GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0002576| platelet degranulation PROS1;SOD1 GO:0046677| response to antibiotic SOD1;CYP1A1 GO:0008284| positive regulation of cell proliferation F2;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0009615| response to virus CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP2E1;CYP2A6;CYP1A2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;PROC;GPX1;NQO1 GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG GO:0045333| cellular respiration CYP1A2 GO:0008283| cell proliferation GPX1;HTR1A;CYP1A1 GO:0006919| activation of caspase activity PPARG;XDH GO:0009636| response to toxin CYP1B1;NQO1;CYP1A1;GPX1;CAT GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;ACAT1;AANAT;PPARG;CYP1A1;NQO1;TRPA1;F7 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0009624| response to nematode CYP1A1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006809| nitric oxide biosynthetic process NQO1;CYP1B1 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0017143| insecticide metabolic process CYP1A1 GO:0043627| response to estrogen stimulus F7;PPARG GO:0070301| cellular response to hydrogen peroxide CYP1B1;NQO1 GO:0007584| response to nutrient CNR1;HMGCR;PPARG;NQO1 GO:0061844| F2;PLA2G1B GO:0070365| hepatocyte differentiation CYP1A1 GO:1900087| CYP1A1 GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;CYP1A1;PPARG GO:0032502| developmental process CYP1A1 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0043010| camera-type eye development CYP1A1 GO:0097267| CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0009725| response to hormone stimulus ACAT1;F7 GO:0006641| triglyceride metabolic process GPX1;CAT;CYP2E1 GO:0010629| negative regulation of gene expression XDH;OPRD1 GO:0042738| exogenous drug catabolic process CYP2A6;CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0031667| response to nutrient levels F7;SOD1 GO:0009635| response to herbicide CYP1A1 GO:0006195| purine nucleotide catabolic process GPX1;XDH GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0060137| maternal process involved in parturition CYP1A1 GO:0019430| removal of superoxide radicals SOD1;NQO1 GO:0007595| lactation SLC29A1;XDH GO:0048565| digestive tract development CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0009692| ethylene metabolic process CYP1A1 GO:0009403| toxin biosynthetic process CYP1A2 GO:0045471| response to ethanol NQO1;CAT;OPRM1;HMGCR;CYP2E1;CNR1;SOD1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;F2;TRPV1 GO:0070988| demethylation CYP1A1 GO:0001889| liver development ACAT1;PROC;CYP1A1 GO:0006805| xenobiotic metabolic process NQO2;CYP2C9;NQO1;CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4;PTGS1 GO:0008152| metabolic process SMPD1;MTHFR;ACAT1 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0006629| lipid metabolic process PPARG;CYP2C9;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1;CYP3A4;NAPEPLD;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 21023:[DB14011 DB08577] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways GO:0007420| brain development FGFR1;ACAT1 GO:0048469| cell maturation PPARG;FGFR1 GO:0001525| angiogenesis PTGS2;FGFR1;CYP1B1 GO:0006351| transcription, DNA-dependent FGFR1;PPARG GO:0010629| negative regulation of gene expression FGFR1;OPRD1 GO:0010976| positive regulation of neuron projection development CNR1;FGFR1 GO:0010468| regulation of gene expression CYP1A2;FGFR1 GO:0048514| blood vessel morphogenesis FGFR1;CYP1B1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FGFR1 GO:0007605| sensory perception of sound SOD1;FGFR1;GPX1 GO:0001657| ureteric bud development FGFR1;CAT GO:0043406| positive regulation of MAP kinase activity HTR2A;FGFR1 GO:0042127| regulation of cell proliferation PTGS1;FGFR1;PTGS2 GO:0030324| lung development CYP1A2;FGFR1 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;FGFR1;HTR2A;PTGS2;HMGCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter FGFR1;PPARG;TRPV4;TRPV1 GO:0006355| regulation of transcription, DNA-dependent PPARG;FGFR1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGFR1 21024:[DB14011 DB07347] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07347|4-(2-Aminoethyl)Benzenesulfonyl Fluoride GAPDH;ATP6V1B2 common genes common pathways GO:0006811| ion transport CACNA1H;TRPV3;GLRA3;TRPV2;CHRNA7;CACNA1G;ATP6V1B2;TRPA1;GLRA1;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;TRPM8 GO:0061844| GAPDH;PLA2G1B GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A2;CYP3A7;PTGS2;HMGCR;GAPDH;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0006915| apoptotic process GPX1;GAPDH;VDAC1 GO:0034220| ion transmembrane transport GLRA3;CHRNA7;ATP6V1B2;GLRA1;TRPA1;TRPV1;GLRB 21025:[DB14011 DB03891] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03891|1,5-Bis(N-Benzyloxycarbonyl-L-Leucinyl)Carbohydrazide CTSK common genes common pathways GO:0045453| bone resorption CTSK;GPR55 GO:1903146| VDAC1;CTSK 21026:[DB14011 DB08420] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08420|1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 21027:[DB14011 DB05214] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05214|KD7040 NOS2 common genes common pathways GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0045776| negative regulation of blood pressure NOS2;CNR1 GO:0002227| innate immune response in mucosa NOS2;PLA2G1B GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR GO:0050796| regulation of insulin secretion NOS2;CNR1 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;NOS2;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT GO:0032496| response to lipopolysaccharide IDO1;NOS2;CYP1A1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;NOS2 GO:0007623| circadian rhythm AANAT;NOS2 GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;NOS2 21028:[DB14011 DB03468] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03468|1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide PNMT common genes common pathways GO:0032259| methylation PNMT;CYP1A2 21029:[DB14011 DB07316] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07316|N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide HSD11B1 common genes common pathways GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;HMGCR;HSD11B1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;HSD11B1;ALOX5;GPX1;PTGS1;CYP1A1;CYP2C9;CRYZ;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1 GO:0030324| lung development HSD11B1;CYP1A2 GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG;NAAA;PTGS1;GPX1;HSD11B1;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4 21030:[DB14011 DB00587] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00587|Cinalukast CYSLTR1 common genes common pathways GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;CYSLTR1;TRPV1;TRPV4 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55;PLA2G1B;CYSLTR1;CACNA1I;SMPD1;GPR18;PPARG GO:0007166| cell surface receptor linked signaling pathway CYSLTR1;TRPV1;TRPA1 GO:0006816| calcium ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;CACNA1I;TRPV4;TRPV1;CYSLTR1;TRPM8;CACNA1G;TRPA1 GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CYSLTR1;PPARG;GPR18 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRD1;OPRM1;CYSLTR1 GO:0007218| neuropeptide signaling pathway CYSLTR1;GLRB;GLRA1;OPRM1;OPRD1;GLRA3 21031:[DB14011 DB05939] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05939|MK-0354 GPER1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;GPER1;PPARG;CYP1B1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;GPER1;TRPV4;TRPV1 GO:0007165| signal transduction GPER1;CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0010629| negative regulation of gene expression GPER1;OPRD1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;GPER1 GO:0006954| inflammatory response TRPV1;IDO1;ALOX15;CNR2;PTGS2;ALOX5;PTGS1;GPER1 GO:1904706| GPER1;PPARG GO:0043401| steroid hormone mediated signaling pathway GPER1;PPARG GO:0019228| regulation of action potential in neuron CACNA1I;CACNA1G;GPER1;CACNA1H GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;GPER1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0007399| nervous system development GPER1;GLRB;SMPD1 GO:0006915| apoptotic process GPER1;GPX1;VDAC1 GO:0050769| positive regulation of neurogenesis OPRM1;GPER1 GO:0070374| positive regulation of ERK1 and ERK2 cascade OPRM1;HMGCR;GPR55;HTR2A;GPER1;CHRNA7;TRPV4;ALOX15 GO:0010628| positive regulation of gene expression GPER1;TRPV4 GO:0071356| cellular response to tumor necrosis factor TRPV1;GPER1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;GPER1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;GPER1 GO:0002376| immune system process IDO1;GPER1 GO:0050728| negative regulation of inflammatory response GPER1;CNR2 GO:0071333| cellular response to glucose stimulus GPER1;SLC29A1 GO:0008284| positive regulation of cell proliferation GPER1;CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GPER1;PPARG;PLA2G1B GO:0045087| innate immune response GPER1;PPARG 21032:[DB14011 DB04180] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04180|4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide CA2 common genes common pathways GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;CA2;PPARG;CYP1A1;TRPA1 GO:0001822| kidney development CAT;CA2 21033:[DB14011 DB00272] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00272|Betazole HRH2 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;CNR1;GPR12;HRH2;OPRM1;CNR2;OPRD1;CHRNA7 GO:0045907| positive regulation of vasoconstriction HRH2;HTR2A;PTGS2 GO:0007613| memory CHRNA7;PTGS2;HRH2;HTR2A;CNR1 GO:0008542| visual learning HMGCR;HRH2 GO:0048565| digestive tract development CYP1A1;HRH2 GO:0006955| immune response CNR2;OPRD1;HRH2 GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;HRH2;HTR1A;GPR55;OPRD1;OPRM1;CNR2;GPR18;PPARG GO:0007187| G-protein signaling, coupled to cyclic nucleotide second messenger CNR1;HRH2;OPRM1;CNR2;OPRD1 21034:[DB14011 DB12662] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12662|Naveglitazar PPARG common genes PPARG common pathways GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;CYP1B1;TRPV1;IDO1 GO:0009409| response to cold TRPA1;PPARG;TRPM8 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process PPARG;CYP2C9;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP3A4;NAPEPLD;HMGCR;CYP1A2;PTGS2;GPX1;NAAA;PTGS1 GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1;CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0045600| positive regulation of fat cell differentiation PPARG;HTR2A GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development SOD1;PPARG GO:0019395| fatty acid oxidation PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;CNR1;HMGCR GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0016525| negative regulation of angiogenesis PPARG GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2 GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;GPR55;HTR1A GO:0015909| long-chain fatty acid transport PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG 21035:[DB14011 DB03179] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03179|Sinapoyl Coenzyme A COMTD1 common genes common pathways GO:0032259| methylation COMTD1;CYP1A2 21036:[DB14011 DB11328] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways 21037:[DB14011 DB00019] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00019|Pegfilgrastim CSF3R;ELANE common genes common pathways GO:0007165| signal transduction PPARG;GPR18;CSF3R;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0009411| response to UV ELANE;CAT GO:0002438| acute inflammatory response to antigenic stimulus ELANE;OPRM1 GO:0006874| cellular calcium ion homeostasis TRPM8;ELANE;TRPV4;GPR12;HTR2A;CHRNA7 GO:0050778| positive regulation of immune response PLA2G1B;ELANE GO:0043406| positive regulation of MAP kinase activity ELANE;HTR2A GO:0032496| response to lipopolysaccharide CYP1A1;ELANE;IDO1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0043312| neutrophil degranulation ELANE;ALOX5;CAT GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;ELANE GO:0007155| cell adhesion CSF3R;CYP1B1 GO:0030593| neutrophil chemotaxis CSF3R;PLA2G1B GO:0048661| positive regulation of smooth muscle cell proliferation ELANE;HMGCR;PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;ELANE 21038:[DB14011 DB13615] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13615|Mifamurtide TLR4;NOD2 common genes common pathways GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0050727| regulation of inflammatory response TLR4;NOD2;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;NOD2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;TLR4;TRPV1;ALOX15;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;TLR4;CAT;NOD2 GO:0006955| immune response TLR4;OPRD1;CNR2 GO:0007165| signal transduction SMPD1;PPARG;TLR4;GPR18;CACNA1I;PLA2G1B;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CHRNA7 GO:0050729| positive regulation of inflammatory response TRPV4;TLR4 GO:0007584| response to nutrient HMGCR;CNR1;NOD2;PPARG GO:0045087| innate immune response TLR4;PPARG;NOD2 GO:0008284| positive regulation of cell proliferation CHRNA7;NOD2;HTR2A;HTR1A;HMGCR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOD2;PLA2G1B;PPARG;TLR4 GO:0032874| positive regulation of stress-activated MAPK cascade HMGCR;NOD2;TLR4 GO:0046330| positive regulation of JNK cascade NOD2;TRPV4;TLR4 GO:0032496| response to lipopolysaccharide CYP1A1;TLR4;IDO1;OPRM1;CYP1A2;CNR2;PTGS2;CNR1 GO:0071407| cellular response to organic cyclic compound CYP1B1;CYP1A1;NOD2 GO:0002376| immune system process NOD2;TLR4;IDO1 GO:0032720| negative regulation of tumor necrosis factor production GPR18;TLR4;CHRNA7 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;TRPV1;PTGS2;OPRM1 GO:0002830| positive regulation of type 2 immune response IDO1;NOD2 GO:0032735| positive regulation of interleukin-12 production IDO1;TLR4 GO:0043406| positive regulation of MAP kinase activity HTR2A;NOD2 GO:0010628| positive regulation of gene expression TRPV4;TLR4 GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;NOD2;CHRNA7;TLR4;TRPV4;ALOX15 GO:0045671| negative regulation of osteoclast differentiation TLR4;GPR55 GO:0000187| activation of MAPK activity SOD1;CHRNA7;NOD2;TLR4;PLA2G1B 21039:[DB14011 DB08029] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08029|N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide MMP3 common genes common pathways 21040:[DB14011 DB09147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways GO:0043312| neutrophil degranulation HBB;ALOX5;FTL;CAT GO:0098869| GSR;HBB;HBA1;CAT;GPX1;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;TRPV1;OPRM1;PTGS2 GO:0042744| hydrogen peroxide catabolic process HBA1;HBB;GPX1;CAT GO:0042542| response to hydrogen peroxide SOD1;GPX1;CAT;TRPA1;HBB;HBA1 GO:0010942| positive regulation of cell death PTGS2;HBB;HBA1 GO:0006879| cellular iron ion homeostasis ABCG2;SOD1;FTL GO:0051291| protein heterooligomerization HBA1;HBB;GLRA1;GLRB GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG;HBB 21041:[DB14011 DB00109] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes CYP2C19 common pathways GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;CYP2D6;CYP2C19;IDO1;GSR;CYP17A1;CYP3A5;ALOX15;CYP1B1;SOD1;CYP3A4;CYP2E1;HMGCR;CYP3A7;PTGS2;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;CYP2E1;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP2E1;CYP1A2 GO:0010193| response to ozone CYP2E1;CAT GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;HMGCR;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP1A1;CYP2C9 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C9;CYP2C19 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0045471| response to ethanol CAT;SOD1;CNR1;CYP2E1;HMGCR;OPRM1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT 21042:[DB14011 DB02371] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways GO:0045087| innate immune response C1S;PPARG GO:0002376| immune system process IDO1;C1S 21043:[DB14011 DB02028] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways GO:0007605| sensory perception of sound TUB;GPX1;SOD1 GO:0050896| response to stimulus TRPA1;TUB;TRPM8 GO:0009725| response to hormone stimulus TUB;ACAT1 21044:[DB14011 DB07209] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes PPARG common pathways GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048511| rhythmic process PPARG;AANAT GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CYP1A2;PTGS2;SOD1 GO:0031000| response to caffeine PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0042593| glucose homeostasis TRPV4;PPARG;CNR1 GO:0031100| organ regeneration PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0015909| long-chain fatty acid transport PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;PPARG;GPR18 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0033189| response to vitamin A CAT;PPARG;CYP1A1 GO:0016525| negative regulation of angiogenesis PPARG GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0030224| monocyte differentiation PPARG GO:0042493| response to drug CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2;HTR2A;SOD1;CYP1A2;PTGS2;CAT GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter TRPV4;TRPV1;PPARG GO:0042594| response to starvation ACAT1;PPARG GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4 GO:0032526| response to retinoic acid PPARG GO:0071306| cellular response to vitamin E PPARG GO:1905563| PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:0030308| negative regulation of cell growth PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient PPARG;HMGCR;CNR1 GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;PTGS2;OPRM1 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0055088| lipid homeostasis PPARG GO:0001890| placenta development PPARG;SOD1 GO:0019395| fatty acid oxidation PPARG GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;AANAT;ACAT1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;CHRNA7 GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0060694| regulation of cholesterol transporter activity PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PPARG GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;PPARG;CYP1A1 GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:1901558| PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:0061614| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0006629| lipid metabolic process NAAA;PTGS1;GPX1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0042953| lipoprotein transport PPARG GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0009409| response to cold PPARG;TRPA1;TRPM8 GO:0048469| cell maturation PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG 21045:[DB14011 DB08583] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways GO:0070301| cellular response to hydrogen peroxide ABL1;CYP1B1 GO:0009791| post-embryonic development ABL1;CYP1A2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV4;TRPV1;ABL1;OPRM1;HTR2A GO:0001934| positive regulation of protein phosphorylation CHRNA7;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;ABL1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;ABL1;IDO1;CYP1B1;TRPV1;SOD1;CNR1;PTGS2 GO:0006915| apoptotic process GPX1;VDAC1;ABL1 GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;ABL1;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0006979| response to oxidative stress ABL1;SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0048538| thymus development ABL1;SOD1 GO:0006355| regulation of transcription, DNA-dependent ABL1;PPARG GO:0043542| endothelial cell migration CYP1B1;ABL1 GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;GSR;ABL1 GO:0042127| regulation of cell proliferation ABL1;PTGS1;PTGS2 GO:0007155| cell adhesion ABL1;CYP1B1 GO:0045087| innate immune response ABL1;PPARG 21046:[DB14011 DB08462] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08462|N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE SRC common genes common pathways GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;SRC;CNR1;SOD1;PTGS2 GO:0042542| response to hydrogen peroxide CAT;SRC;GPX1;SOD1;TRPA1 GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0031667| response to nutrient levels SOD1;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0032869| cellular response to insulin stimulus SRC;PLA2G1B;PPARG GO:0045453| bone resorption GPR55;SRC GO:0007165| signal transduction SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;HTR1A;GPR55;SRC;CHRNA7 GO:0070542| response to fatty acid PTGS2;SRC;CAT GO:0008283| cell proliferation CYP1A1;GPX1;SRC;HTR1A GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0009615| response to virus CYP1A1;SRC GO:0043066| negative regulation of apoptotic process CAT;SRC;GPX1;SOD1;PTGS2;HMGCR GO:0009612| response to mechanical stimulus PPARG;TRPV4;SRC GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response SRC;PPARG GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;SOD1;HTR2A;SRC;CAT GO:0016236| macroautophagy VDAC1;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade SRC;GPX1 GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0002376| immune system process SRC;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7;SRC GO:0010628| positive regulation of gene expression SRC;TRPV4 GO:0043406| positive regulation of MAP kinase activity SRC;HTR2A GO:0045892| negative regulation of transcription, DNA-dependent PPARG;SRC 21047:[DB14011 DB00721] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0007612| learning PTGS2;VDAC1;BCHE GO:0032496| response to lipopolysaccharide IDO1;CYP1A1;MAOB;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0001508| regulation of action potential KCNMB2;KCNMB4;KCNMB3;GLRA1;CACNA1G GO:0086016| SCN10A;CACNA1G GO:0060079| regulation of excitatory postsynaptic membrane potential OPRM1;GLRA3;SLC29A1;CHRNA2;CHRNA7;GLRA1;GRIN3A;TRPV1;GLRB GO:0007626| locomotory behavior SLC6A3;OPRM1;SOD1 GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;ABCC1;MAOB;BCHE;TRPA1;CYP1A1;PPARG;SLC6A3;ABCG2 GO:0022900| electron transport chain MAOB;IDO1;GSR;CYP1A2 GO:0055114| oxidation-reduction process CAT;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;PTGS2;CYP3A7;MAOA;CYP1A2;HMGCR;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CRYZ;MAOB GO:0034465| response to carbon monoxide SOD1;KCNMA1 GO:0035094| response to nicotine SLC6A3;CNR1;CHRNA2;CHRNA7 GO:0071363| cellular response to growth factor stimulus CAT;OPRD1;HTR3A;TRPV1 GO:0071456| cellular response to hypoxia KCNMB1;OPRD1;PTGS2;SLC29A1 GO:0007568| aging CAT;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;SLC6A3;CYP1A1;KCNMB1 GO:0002376| immune system process IDO1;KCNN4 GO:0042391| regulation of membrane potential CACNA1H;KCNMA1;GLRB;CACNA1G;GLRA1 GO:0051591| response to cAMP AANAT;SLC6A3 GO:0034220| ion transmembrane transport HTR3A;GLRB;TRPV1;GLRA1;TRPA1;GRIN3A;CHRNA7;CHRNA2;GLRA3 GO:0050665| hydrogen peroxide biosynthetic process MAOB;CYP1A1;CYP1A2;SOD1 GO:0006884| cell volume homeostasis TRPV4;KCNN4 GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;KCNMA1;VDAC1;TRPV4;CACNA1I;TRPV1;SLC6A3;TRPM8;ABCG2;ABCC1;CACNA1G;SCN10A;TRPA1 GO:0050714| positive regulation of protein secretion PLA2G1B;KCNN4 GO:0042220| response to cocaine CNR1;OPRM1;SMPD1;SLC6A3;HTR3A GO:0001666| response to hypoxia KCNMA1;CAT;CHRNA7;CYP1A1 GO:0006970| response to osmotic stress KCNMA1;TRPV4 GO:0045471| response to ethanol GRIN3A;MAOB;SLC6A3;HTR3A;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0051592| response to calcium ion AANAT;KCNMA1;KCNMB1 GO:0019228| regulation of action potential in neuron CACNA1G;SCN10A;CACNA1I;KCNMB3;KCNMB4;CACNA1H;KCNMB2 GO:0035725| sodium ion transmembrane transport CACNA1H;CACNA1G;SCN10A;CACNA1I GO:0019233| sensory perception of pain TRPV1;TRPA1;SCN10A;CNR1;HTR2A;PTGS2;CNR2;OPRM1;OPRD1 GO:0043065| positive regulation of apoptotic process PTGS2;KCNMA1;CNR1;SOD1;TRPV1;CYP1B1;IDO1;SMPD1;PPARG GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC6A3 GO:0002027| regulation of heart rate SCN10A;CACNA1G GO:0071361| cellular response to ethanol KCNMB1;GLRA1 GO:0060078| regulation of postsynaptic membrane potential CHRNA2;CHRNA7 GO:0007268| synaptic transmission GLRA3;HTR2A;KCNMB4;OPRM1;KCNMB2;OPRD1;KCNN1;GLRA1;KCNMB1;CACNA1G;GLRB;VDAC1;HTR3A;KCNMB3 GO:0006816| calcium ion transport TRPA1;GRIN3A;CACNA1G;KCNN4;TRPM8;TRPV1;CACNA1I;TRPV4;TRPV3;CACNA1H;CHRNA7;TRPV2 GO:0007595| lactation SLC6A3;SLC29A1 GO:0086010| CACNA1H;CACNA1I;SCN10A;CACNA1G GO:0007600| sensory perception OPRM1;TRPV2;SCN10A GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0045332| phospholipid translocation KCNN4;ABCC1 GO:0060083| smooth muscle contraction involved in micturition TRPV1;KCNMA1 GO:0034765| regulation of ion transmembrane transport KCNMA1;CACNA1H;SCN10A;CACNA1G;CACNA1I GO:0070588| calcium ion transmembrane transport CACNA1H;OPRM1;TRPV3;TRPV2;CHRNA7;CACNA1G;GRIN3A;TRPA1;TRPV4;CACNA1I;TRPV1;TRPM8 GO:0007165| signal transduction CHRNA7;CHRNA2;CNR1;GPR12;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2;HTR3A;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0051412| response to corticosterone stimulus MAOB;AANAT GO:0065009| regulation of molecular function TRPV1;KCNMB3;KCNMB1;KCNMB4;KCNMB2 GO:0006811| ion transport GRIN3A;TRPA1;GLRA1;KCNMB1;CACNA1G;SCN10A;KCNN4;TRPM8;KCNN3;TRPV4;CACNA1I;GLRB;VDAC1;TRPV1;HTR3A;KCNMB3;GLRA3;KCNMA1;KCNMB4;CACNA1H;KCNMB2;TRPV3;KCNN1;CHRNA7;KCNN2;TRPV2;CHRNA2 GO:0009636| response to toxin CAT;GPX1;CYP1B1;CYP1A1;MAOB GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;SLC6A3;TRPA1;CYP1A1;PPARG GO:0010269| response to selenium ion MAOB;GPX1 GO:0042053| regulation of dopamine metabolic process HTR1A;SLC6A3 GO:0060371| regulation of atrial cardiomyocyte membrane depolarization SCN10A;CACNA1G GO:0051291| protein heterooligomerization GLRA1;GLRB;CHRNA2 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;BCHE;PPARG;CYP1B1 21048:[DB14011 DB14507] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007623| circadian rhythm AANAT;GSK3B GO:0060079| regulation of excitatory postsynaptic membrane potential SLC29A1;GSK3B;CHRNA7;GRIA3;OPRM1;GLRA3;GLRB;TRPV1;GLRA1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT;GSK3B GO:0006810| transport GRIA3;TRPV2;ABCC1;TRPV1;CACNA1I;ABCG2 GO:0034220| ion transmembrane transport GRIA3;GLRA3;CHRNA7;GLRA1;TRPA1;TRPV1;GLRB GO:0010628| positive regulation of gene expression TRPV4;GSK3B GO:0048511| rhythmic process PPARG;GSK3B;AANAT GO:0035556| intracellular signal transduction GSK3B;PLA2G1B GO:0007399| nervous system development GSK3B;GLRB;SMPD1 GO:0007165| signal transduction CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;IMPA2;IMPA1 GO:0006811| ion transport TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPM8;CACNA1G;TRPA1;GLRA1;TRPV2;CHRNA7;CACNA1H;GRIA3;TRPV3;GLRA3 21049:[DB14011 DB03932] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03932|LFA703 ITGAL common genes common pathways GO:0006954| inflammatory response PTGS1;ALOX5;CNR2;PTGS2;ITGAL;TRPV1;IDO1;ALOX15 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;ITGAL;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 GO:0043312| neutrophil degranulation ALOX5;CAT;ITGAL GO:0007155| cell adhesion CYP1B1;ITGAL 21050:[DB14011 DB03395] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03395|Enalkiren REN common genes common pathways GO:0048469| cell maturation PPARG;REN GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;REN GO:0032496| response to lipopolysaccharide CNR2;PTGS2;OPRM1;CYP1A2;CNR1;CYP1A1;REN;IDO1 GO:0035902| response to immobilization stress REN;CYP1A1;PPARG;CYP1A2 GO:0001822| kidney development CAT;REN GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;TRPA1;REN;CYP1A1;PPARG;SMPD1;ABCC1;ABCG2 GO:0051591| response to cAMP REN;AANAT GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;REN;CYP1A2;PTGS2;SOD1 21051:[DB14011 DB04152] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04152|2-Amino-3-(3-Hydroxy-7,8-Dihydro-6h-Cyclohepta[D]-4-Isoxazolyl)Propionic Acid GRIA2 common genes common pathways GO:0007268| synaptic transmission VDAC1;GLRB;GLRA1;CACNA1G;GRIA2;GLRA3;HTR2A;OPRD1;OPRM1 GO:0006811| ion transport GLRA3;TRPV3;CACNA1H;CHRNA7;TRPV2;GRIA2;TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;VDAC1;GLRB;TRPV4;CACNA1I GO:0007165| signal transduction OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;GRIA2;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;GRIA2;SLC29A1;GLRA3;OPRM1;TRPV1;GLRB;GLRA1 GO:0034220| ion transmembrane transport CHRNA7;GRIA2;GLRA3;TRPV1;GLRB;TRPA1;GLRA1 21052:[DB14011 DB11071] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0070542| response to fatty acid CAT;PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;PTGS2;CYP1A2 GO:0033280| response to vitamin D PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;CYP1B1;PPARG GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0019233| sensory perception of pain PTGS2;CNR2;OPRM1;OPRD1;CNR1;HTR2A;TRPA1;TRPV1 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;PTGS1 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;TRPV1;CYP1B1;PPARG;SMPD1;CNR1;SOD1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;PPARG;TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;HMGCR;CYP1A2;PTGS2;NAPEPLD;CYP3A4;NAAA;PTGS1;GPX1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0006954| inflammatory response PTGS2;CNR2;PTGS1;ALOX5;TRPV1;IDO1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0034605| cellular response to heat TRPV4;TRPV1;PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2;CYP1A2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0007568| aging CYP1A1;PTGS2;HMGCR;NAPEPLD;CNR1;SOD1;HTR2A;CAT GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia SLC29A1;OPRD1;PTGS2 GO:0098869| PTGS2;CAT;PTGS1;GPX1;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;TRPV1 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;TRPA1;CYP1A1;PPARG GO:0071318| cellular response to ATP PTGS2;SOD1;TRPV1 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CYP1A2;OPRM1;CNR2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning PTGS2;VDAC1 GO:0071284| cellular response to lead ion PTGS2 GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug PTGS2;CYP1A2;SOD1;HTR2A;CAT;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCG2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;CYP1B1;ALOX15;CYP3A5;CYP17A1;GSR;IDO1;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0019372| lipoxygenase pathway ALOX5;GPX1;PTGS2;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009750| response to fructose stimulus PTGS2 21053:[DB14011 DB08191] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways GO:0035556| intracellular signal transduction PLA2G1B;SGK1 GO:0008217| regulation of blood pressure PPARG;SGK1;PTGS2;SOD1;PTGS1 GO:0042127| regulation of cell proliferation SGK1;PTGS2;PTGS1 GO:0006915| apoptotic process SGK1;VDAC1;GPX1 GO:0034220| ion transmembrane transport CHRNA7;GLRA3;GLRB;TRPV1;SGK1;GLRA1;TRPA1 21054:[DB14011 DB13257] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes PTGS1;PTGS2;CAT common pathways GO:0045776| negative regulation of blood pressure CNR1;NOS2 GO:0045471| response to ethanol CAT;CNR1;SOD1;OPRM1;HMGCR GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0006351| transcription, DNA-dependent PCBD1;PPARG GO:0019233| sensory perception of pain TRPV1;TRPA1;HTR2A;CNR1;CNR2;PTGS2;OPRM1;OPRD1 GO:0001889| liver development ACO2;CYP1A1;ACAT1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0007399| nervous system development SDHA;SMPD1;GLRB GO:0006629| lipid metabolic process TRPV1;PLA2G1B;DAGLA;CYP2D6;ALOX15;PPARG;CYP2C9;PTGS1;NAAA;GPX1;HMGCR;CYP1A2;PTGS2;CYP3A4;NAPEPLD GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TRPV1;CYP1B1;IDO1;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation OPRM1;PTGS2;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0042542| response to hydrogen peroxide CAT;GPX1;SOD1;TRPA1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP3A5 GO:1990776| PTGS2 GO:0008152| metabolic process ACAT1;RRM1;ACO2;SMPD1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0046219| indolalkylamine biosynthetic process AANAT;TPH1 GO:0006195| purine nucleotide catabolic process GPX1;XDH GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0010629| negative regulation of gene expression NOS2;XDH;OPRD1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019430| removal of superoxide radicals SOD1;MPO GO:0007595| lactation XDH;SLC29A1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006879| cellular iron ion homeostasis ABCG2;TF;SOD1;CP;FTH1;FTL GO:0051289| protein homotetramerization CAT;PCBD1;TRPM8;TRPV1;TRPA1;CRYZ GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B GO:0006954| inflammatory response PTGS2;CNR2;PTGS1;ALOX5;TRPV1;ALOX15;IDO1 GO:0010942| positive regulation of cell death PTGS2 GO:0006955| immune response OPRD1;CNR2;FTH1 GO:0007613| memory HTR2A;CNR1;PTGS2;CHRNA7 GO:0050796| regulation of insulin secretion NOS2;CNR1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0001649| osteoblast differentiation CAT GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0019216| regulation of lipid metabolic process CYP4A11;HMGCR;CNR1;PPARG;CYP1A1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0045454| cell redox homeostasis NOS2;GSR;GPX1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;PTGS1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP4A11;CYP1A2 GO:0006641| triglyceride metabolic process CAT;GPX1 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0032868| response to insulin stimulus TRPV4;AANAT;CAT GO:0015949| nucleobase-containing small molecule interconversion RRM1;GSR GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014854| response to inactivity CAT GO:0033591| response to L-ascorbic acid CAT GO:0006809| nitric oxide biosynthetic process NOS2;CYP1B1 GO:0001895| retina homeostasis TF;SOD1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0006811| ion transport GLRA3;CACNA1H;TF;TRPV3;CHRNA7;CP;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1 GO:0033280| response to vitamin D PTGS2 GO:0032088| negative regulation of NF-kappaB transcription factor activity CAT;CYP1B1 GO:0006919| activation of caspase activity PPARG;XDH GO:0009411| response to UV CAT GO:0009636| response to toxin CYP1B1;CYP1A1;GPX1;CAT GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0014070| response to organic cyclic compound TRPA1;CYP1A1;PPARG;PTGS2;CYP1A2;AANAT;ACAT1 GO:0009650| UV protection GPX1;CAT GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;FTH1;PPARG;CYP1B1 GO:0008217| regulation of blood pressure PPARG;PTGS2;SOD1;PTGS1 GO:0014823| response to activity CAT GO:0051781| positive regulation of cell division CAT GO:0045600| positive regulation of fat cell differentiation HTR2A;TPH1;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0051291| protein heterooligomerization PCBD1;GLRA1;GLRB GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0030199| collagen fibril organization P4HA1;CYP1B1 GO:0034599| cellular response to oxidative stress GSR;GPX1;CAT;SOD1 GO:0071284| cellular response to lead ion PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;NOS2 GO:0008203| cholesterol metabolic process CAT;HMGCR GO:0007612| learning VDAC1;PTGS2 GO:0007623| circadian rhythm TPH1;NOS2;AANAT GO:0032496| response to lipopolysaccharide MPO;CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;NOS2;CYP1A1 GO:0000302| response to reactive oxygen species SOD1;GPX1;CAT GO:0033197| response to vitamin E CAT GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0020027| hemoglobin metabolic process CAT GO:0010288| response to lead ion CAT GO:0035902| response to immobilization stress CYP1A2;CYP1A1;PPARG;TPH1 GO:0043312| neutrophil degranulation ALOX5;MPO;FTH1;FTL;CAT GO:0002576| platelet degranulation TF;SOD1 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0001822| kidney development CAT GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2;CYP4A11 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;MPO;GPX1;CAT GO:0009612| response to mechanical stimulus PPARG;TRPV4;MPO GO:0035900| response to isolation stress NAPEPLD;ACO2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0009642| response to light intensity CAT GO:0055114| oxidation-reduction process P4HA1;TPH1;RRM1;CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;SUOX;CYP2C9;CYP1A1;NOS2;CRYZ;NDUFS8;FTH1;PCBD1;CP;ALOX5;MPO;PTGS1;GPX1;CAT;PTGS2;CYP3A7;CYP1A2;CYP4A11;HMGCR;XDH;CYP3A4;TMLHE;SDHA;SOD1 GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;CYP1A1;PPARG;TRPA1;SMPD1;ABCC1;ABCG2 GO:0006691| leukotriene metabolic process ALOX5;CYP4A11;ALOX15;ABCC1 GO:0006355| regulation of transcription, DNA-dependent PPARG;PCBD1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0032094| response to food MPO;OPRM1;CYP1A1 GO:0022900| electron transport chain IDO1;GSR;XDH;CYP1A2;SDHA GO:0006631| fatty acid metabolic process ALOX15;PTGS2;CYP4A11;PTGS1 GO:0045893| positive regulation of transcription, DNA-dependent PCBD1;PPARG GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0009750| response to fructose stimulus PTGS2 GO:0055093| response to hyperoxia CYP1A1;CAT GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019369| arachidonic acid metabolic process FAAH;CYP4A11;CYP1B1;CYP2D6;DAGLA;ALOX15 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0097756| PTGS2;HMGCR GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0007568| aging CAT;MPO;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CYP1A1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT GO:0009060| aerobic respiration CAT GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:1902219| PTGS2 GO:0071363| cellular response to growth factor stimulus TRPV1;CAT;OPRD1 GO:0034605| cellular response to heat PTGS2;TRPV1;TRPV4 GO:0098869| PTGS2;CAT;PTGS1;GPX1;GSR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;MPO;GPX1;PTGS1;NDUFS8 GO:0080184| response to phenylpropanoid CAT GO:0034612| response to tumor necrosis factor PTGS2 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0046686| response to cadmium ion CAT GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;PTGS2;CYP1A2;SOD1 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051262| protein tetramerization HMGCR;CAT GO:0001657| ureteric bud development CAT GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0010193| response to ozone CAT 21055:[DB14011 DB04440] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04440|Nebularine ADA common genes common pathways GO:0001890| placenta development ADA;SOD1;PPARG GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0001889| liver development CYP1A1;ADA;ACAT1 GO:0042542| response to hydrogen peroxide TRPA1;SOD1;GPX1;ADA;CAT GO:0001666| response to hypoxia CYP1A1;ADA;CAT;CHRNA7 GO:0007568| aging CYP1A1;NAPEPLD;CNR1;HTR2A;SOD1;PTGS2;HMGCR;CAT;ADA GO:0042493| response to drug SOD1;HTR2A;CYP1A2;PTGS2;CAT;ADA;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;ABCG2 GO:0050728| negative regulation of inflammatory response ADA;CNR2 GO:0043278| response to morphine CNR1;OPRM1;ADA GO:0033197| response to vitamin E ADA;CAT GO:0030324| lung development CYP1A2;ADA GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;ADA;GPX1 GO:0007155| cell adhesion ADA;CYP1B1 21056:[DB14011 DB03851] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03851|Carbazole Butanoic Acid FABP4 common genes common pathways GO:0071356| cellular response to tumor necrosis factor FABP4;TRPV1 GO:0045892| negative regulation of transcription, DNA-dependent FABP4;PPARG GO:0050729| positive regulation of inflammatory response FABP4;TRPV4 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0050872| white fat cell differentiation FABP4;PPARG 21057:[DB14011 DB00056] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0032693| negative regulation of interleukin-10 production IDO1;FCGR2B GO:0006955| immune response CNR2;FCGR3A;OPRD1;FCGR2C;C1QC;FCGR1A;C1R;FCGR2B;FCGR3B GO:0016032| viral reproduction HTR2A;VDAC1;FCGR2B GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;FCGR2B;IDO1;ALOX15;TRPV1 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;CD33;OPRM1;PTGS2 GO:0007165| signal transduction PLA2G1B;CACNA1I;FCGR1A;SMPD1;GPR18;PPARG;FCGR2B;CHRNA7;CD33;FCGR2C;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A GO:0046330| positive regulation of JNK cascade TRPV4;FCGR2B GO:0043312| neutrophil degranulation FCGR2A;FCGR3B;ALOX5;CD33;CAT GO:0007155| cell adhesion CYP1B1;CD33 GO:0045087| innate immune response FCGR1A;PPARG;C1R;C1QB;C1QA;C1QC;C1S GO:0002376| immune system process C1QA;C1S;C1QC;FCGR2A;FCGR1A;IDO1;C1QB;C1R 21058:[DB14011 DB08478] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0007623| circadian rhythm AANAT;TYMS GO:0034097| response to cytokine stimulus PTGS2;AANAT;TYMS GO:0032259| methylation TYMS;CYP1A2 GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;PPARG;CYP1A1;TYMS;ABCC1;SMPD1;ABCG2 GO:0033189| response to vitamin A PPARG;TYMS;CYP1A1;CAT GO:0007568| aging TYMS;CYP1A1;CAT;HMGCR;PTGS2;CNR1;SOD1;HTR2A;NAPEPLD GO:0045471| response to ethanol OPRM1;HMGCR;SOD1;CNR1;CAT;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0015949| nucleobase-containing small molecule interconversion GSR;TYMS GO:0009636| response to toxin CYP1B1;TYMS;CYP1A1;CAT;GPX1 GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;TYMS;CYP1A1;PPARG;TRPA1 21059:[DB14011 DB07931] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;AKR1C1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;ALOX5;GPX1;PTGS1 GO:0006355| regulation of transcription, DNA-dependent PPARG;NR1I2;NR1I3;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;PPARG;ESR1 GO:0006367| transcription initiation from RNA polymerase II promoter ESR1;NR1I3;PPARG;NR1I2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger ESR1;HTR2A;OPRM1;OPRD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;NR1I2;PPARG;ESR1;NR1I3 GO:0030855| epithelial cell differentiation AKR1C1;VDAC1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG;NR1I2;NR1I3 GO:0010628| positive regulation of gene expression NR1I2;TRPV4 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;ESR1;CAT GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;NR1I2;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5 GO:0051260| protein homooligomerization GLRA3;AKR1C1;ACAT1;GLRA1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;OPRM1;PTGS2;ESR1 GO:0042574| retinal metabolic process AKR1C1;CYP1B1 GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0010629| negative regulation of gene expression ESR1;OPRD1 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9;NR1I2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR1 GO:0042448| progesterone metabolic process CYP17A1;AKR1C1 GO:0043401| steroid hormone mediated signaling pathway PPARG;NR1I2;ESR1;NR1I3 GO:0006351| transcription, DNA-dependent PPARG;NR1I2;NR1I3;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter ESR1;PPARG GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006805| xenobiotic metabolic process NR1I2;CYP2C9;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;AKR1C1;CYP3A4;PTGS1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0001523| retinoid metabolic process NAPEPLD;AKR1C1 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;ESR1;HTR2A;TRPV4;TRPV1 GO:0042908| xenobiotic transport ABCG2;NR1I2;ABCC1 GO:0007165| signal transduction SMPD1;NR1I2;GPR18;PPARG;PLA2G1B;CACNA1I;NR1I3;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;GPR55;HTR1A;ESR1;CHRNA7 21060:[DB14011 DB05950] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05950|Contulakin-G CACNA1B common genes common pathways GO:0006810| transport CACNA1B;TRPV2;ABCC1;CACNA1I;TRPV1;ABCG2 GO:0055085| transmembrane transport TRPV1;VDAC1;TRPV4;CACNA1I;TRPM8;ABCG2;ABCC1;CACNA1G;TRPA1;TRPV2;TRPV3;CACNA1H;CACNA1B GO:0007269| neurotransmitter secretion NAAA;CACNA1B GO:0007626| locomotory behavior CACNA1B;SOD1;OPRM1 GO:0048265| response to pain TRPV1;TRPA1;CACNA1B GO:0070588| calcium ion transmembrane transport TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;OPRM1;CACNA1B GO:0034765| regulation of ion transmembrane transport CACNA1B;CACNA1H;CACNA1G;CACNA1I GO:0006811| ion transport TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;TRPV3;CACNA1H;CACNA1B;GLRA3 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2;CACNA1B;SOD1 GO:0008016| regulation of heart contraction CACNA1B;CACNA1H GO:0007268| synaptic transmission OPRD1;OPRM1;GLRA3;CACNA1B;HTR2A;VDAC1;GLRB;CACNA1G;GLRA1 GO:0006816| calcium ion transport TRPV1;CACNA1I;TRPV4;TRPM8;CACNA1G;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;CACNA1B GO:0086010| CACNA1B;CACNA1H;CACNA1G;CACNA1I GO:0051924| regulation of calcium ion transport CACNA1B;OPRD1 21061:[DB14011 DB04371] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04371|AL6528 CA2 common genes common pathways GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT GO:0009268| response to pH CA2;TRPV1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;CA2;SOD1;CYP1A2;PTGS2 GO:0001822| kidney development CA2;CAT 21062:[DB14011 DB07112] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways GO:0006879| cellular iron ion homeostasis ABCG2;EGLN1;SOD1 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A5;ALOX15;CYP17A1;EGLN1;CYP2D6;IDO1;GSR;CYP2C19;CYP1B1;CYP1A1;CYP2C9;CRYZ GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;EGLN1;PPARG GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;EGLN1 GO:1901214| EGLN1;CHRNA7 21063:[DB14011 DB02479] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02479|(R)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways GO:0001822| kidney development CAT;CA2 GO:0010033| response to organic substance CA2;TRPA1;CYP1A1;PPARG;SOD1;PTGS2;CYP1A2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0009268| response to pH CA2;TRPV1 GO:0043627| response to estrogen stimulus PPARG;CA2 GO:0010043| response to zinc ion CA2;AANAT 21064:[DB14011 DB01827] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways GO:0090280| positive regulation of calcium ion import TRPV2;LGALS3;TRPV3 GO:0061844| PLA2G1B;LGALS3 GO:0030855| epithelial cell differentiation LGALS3;PPARG;VDAC1 GO:0002376| immune system process IDO1;LGALS3 GO:0030593| neutrophil chemotaxis PLA2G1B;LGALS3 GO:0045087| innate immune response PPARG;LGALS3 GO:0043312| neutrophil degranulation LGALS3;ALOX5;CAT 21065:[DB14011 DB11219] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways GO:0006367| transcription initiation from RNA polymerase II promoter AR;ESR1;PGR;ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent AR;ESR1;PGR;ESR2;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;ESR2;ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;PLA2G1B;PGR;PPARG;AR;ESR1 GO:0008284| positive regulation of cell proliferation AR;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR1;AR;PPARG;ESR2;TRPV4;TRPV1 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;ESR1;HTR2A GO:0007283| spermatogenesis CNR1;SOD1;AR GO:0010628| positive regulation of gene expression TRPV4;AR GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1;ESR1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1;CAT GO:0010468| regulation of gene expression AR;CYP1A2 GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;TRPV2;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;AR;PLA2G1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;PPARG;ESR2 GO:0010629| negative regulation of gene expression OPRD1;ESR1;PGR GO:0008209| androgen metabolic process CYP3A4;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG;ESR1;AR GO:0006351| transcription, DNA-dependent PGR;ESR2;PPARG;AR;ESR1 GO:0043401| steroid hormone mediated signaling pathway ESR1;AR;PPARG;PGR;ESR2 GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;ESR1 GO:0043627| response to estrogen stimulus ESR1;PPARG GO:0008285| negative regulation of cell proliferation AR;PTGS2;OPRM1;CYP1B1;PPARG GO:0008283| cell proliferation CYP1A1;HTR1A;AR;GPX1 GO:0007548| sex differentiation AR;CYP17A1 GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PGR;PLA2G1B;ESR2;CNR2;OPRM1;OPRD1;ESR1;GPR55;HTR1A;HTR2A;GPR12;CNR1;AR;CHRNA7 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;ESR1;OPRM1;TRPV1;TRPV4 21066:[DB14011 DB07016] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07016|(3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline F2 common genes common pathways GO:0061844| PLA2G1B;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;F2;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;HMGCR;HTR1A;HTR2A;F2 21067:[DB14011 DB03732] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03732|Etheno-Nadp BST1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;BST1 GO:0007165| signal transduction OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;CACNA1I;PLA2G1B;BST1 GO:0008284| positive regulation of cell proliferation BST1;CHRNA7;HMGCR;PTGS2;HTR2A;HTR1A GO:0043312| neutrophil degranulation BST1;ALOX5;CAT 21068:[DB14011 DB05183] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05183|MLN0415 IKBKB common genes common pathways GO:0071356| cellular response to tumor necrosis factor TRPV1;IKBKB GO:0045893| positive regulation of transcription, DNA-dependent IKBKB;PPARG GO:0045087| innate immune response PPARG;IKBKB GO:0043066| negative regulation of apoptotic process IKBKB;SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0009615| response to virus IKBKB;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;IKBKB GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;IKBKB;PLA2G1B GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;ALOX5;PTGS1;CNR2;PTGS2;IKBKB 21069:[DB14011 DB03382] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes SOD1 common pathways GO:0045471| response to ethanol CAT;CNR1;SOD1;HMGCR;OPRM1 GO:0048678| response to axon injury SOD1 GO:0008089| anterograde axon cargo transport SOD1 GO:0045541| negative regulation of cholesterol biosynthetic process SOD1 GO:0008090| retrograde axon cargo transport SOD1 GO:0000303| response to superoxide SOD1 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0060088| auditory receptor cell stereocilium organization SOD1 GO:0042542| response to hydrogen peroxide TRPA1;GPX1;CAT;SOD1 GO:0060052| neurofilament cytoskeleton organization SOD1 GO:0043524| negative regulation of neuron apoptosis SOD1 GO:0045859| regulation of protein kinase activity SOD1 GO:0031667| response to nutrient levels SOD1 GO:0019430| removal of superoxide radicals SOD1 GO:0006879| cellular iron ion homeostasis SOD1;ABCG2 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1 GO:0019226| transmission of nerve impulse SOD1 GO:0043087| regulation of GTPase activity SOD1 GO:0002262| myeloid cell homeostasis SOD1 GO:0072593| reactive oxygen species metabolic process SOD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0040014| regulation of multicellular organism growth SOD1 GO:0001975| response to amphetamine SOD1;CNR2 GO:0032287| peripheral nervous system myelin maintenance SOD1 GO:0060047| heart contraction SOD1;GPX1 GO:0001819| positive regulation of cytokine production SOD1 GO:0051881| regulation of mitochondrial membrane potential OPRD1;SOD1 GO:0001895| retina homeostasis SOD1 GO:0046620| regulation of organ growth SOD1 GO:0032930| positive regulation of superoxide anion generation SOD1 GO:0035865| cellular response to potassium ion CACNA1H;SOD1 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;PPARG GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0006749| glutathione metabolic process GSR;GPX1;SOD1 GO:0001890| placenta development SOD1;PPARG GO:0097332| SOD1 GO:0034599| cellular response to oxidative stress GSR;SOD1;GPX1;CAT GO:0000302| response to reactive oxygen species CAT;GPX1;SOD1 GO:0071318| cellular response to ATP SOD1;PTGS2;TRPV1 GO:0002576| platelet degranulation SOD1 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0007626| locomotory behavior SOD1;OPRM1 GO:1902177| SOD1 GO:0035722| interleukin-12-mediated signaling pathway SOD1 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT GO:0060087| relaxation of vascular smooth muscle SOD1 GO:0055114| oxidation-reduction process CRYZ;CYP1A1;CYP2C9;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CYP1B1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CAT;PTGS1;ALOX5;GPX1 GO:0007569| cell aging SOD1 GO:0042493| response to drug CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;ABCG2;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0033081| regulation of T cell differentiation in thymus SOD1 GO:0006801| superoxide metabolic process SOD1 GO:0034465| response to carbon monoxide SOD1 GO:0007568| aging CYP1A1;HMGCR;PTGS2;HTR2A;SOD1;CNR1;NAPEPLD;CAT GO:0042554| superoxide anion generation SOD1 GO:0007605| sensory perception of sound SOD1;GPX1 GO:0043085| positive regulation of catalytic activity SOD1 GO:0048538| thymus development SOD1 GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0000187| activation of MAPK activity CHRNA7;SOD1;PLA2G1B GO:0001541| ovarian follicle development SOD1 GO:0050665| hydrogen peroxide biosynthetic process CYP1A2;SOD1;CYP1A1 GO:0046716| muscle cell homeostasis SOD1 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;SOD1;PTGS2;CYP1A2 GO:0046688| response to copper ion SOD1;AANAT GO:0007283| spermatogenesis CNR1;SOD1 21070:[DB14011 DB06637] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0007268| synaptic transmission OPRM1;OPRD1;GLRA3;HTR2A;KCND2;GLRB;VDAC1;KCNA1;CACNA1G;GLRA1 GO:0050966| detection of mechanical stimulus involved in sensory perception of pain HTR2A;TRPA1;KCNA1 GO:0001964| startle response GLRA1;KCNA1;GLRB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0086091| KCND3;KCNA5;CACNA1G GO:0045471| response to ethanol CAT;HMGCR;OPRM1;CNR1;SOD1;KCNC2;CYP2E1 GO:0007405| neuroblast proliferation KCNA1;DAGLA GO:0019228| regulation of action potential in neuron CACNA1I;KCNA1;CACNA1G;CACNA1H;KCNA2;KCND2 GO:0019233| sensory perception of pain KCND2;HTR2A;CNR1;OPRD1;CNR2;PTGS2;OPRM1;KCNA2;TRPA1;TRPV1 GO:0042542| response to hydrogen peroxide TRPA1;KCNA5;SOD1;CAT;GPX1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP3A7;PTGS1 GO:0042136| neurotransmitter biosynthetic process DAGLA;SLC22A2 GO:0006811| ion transport KCNC2;KCNA4;KCNC1;KCNA6;KCND2;GLRA3;KCNB2;KCNA2;CACNA1H;TRPV3;KCND3;KCND1;CHRNA7;TRPV2;KCNA10;KCNC3;TRPA1;GLRA1;KCNA3;CACNA1G;KCNB1;TRPM8;SLC22A2;KCNA5;TRPV1;KCNA7;GLRB;TRPV4;CACNA1I;VDAC1;KCNA1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;KCNC2;PPARG;CYP1A1;TRPA1 GO:0043267| negative regulation of potassium ion transport KCNA5;HTR2A GO:0009636| response to toxin CAT;GPX1;KCNC1;KCNC2;CYP1B1;CYP1A1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A2 GO:0051291| protein heterooligomerization GLRA1;GLRB;KCNC2 GO:0006812| cation transport TRPM8;SLC22A2 GO:1900087| KCNA5;CYP1A1 GO:0050796| regulation of insulin secretion KCNA5;KCNB1;CNR1;KCNC2 GO:0034765| regulation of ion transmembrane transport KCNA6;KCND2;KCNC2;KCNA4;KCNC1;KCNB2;CACNA1H;KCNA2;KCND3;KCND1;KCNA10;KCNC3;KCNA3;CACNA1G;KCNA5;KCNB1;KCNA1;KCNA7;CACNA1I GO:0007420| brain development KCNA1;ACAT1;KCNC1 GO:0045956| positive regulation of calcium ion-dependent exocytosis CACNA1H;CACNA1I;KCNB1;CACNA1G GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0065009| regulation of molecular function TRPV1;KCNA5 GO:0042493| response to drug CAT;CYP1A2;PTGS2;CYP2E1;SOD1;HTR2A;ABCG2;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1 GO:0050905| neuromuscular process GLRA1;KCNA1;GLRB GO:0009642| response to light intensity CAT;KCNC2;KCNC1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP2E1;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9 GO:0055093| response to hyperoxia CAT;CYP1A1;KCNA5 GO:0010243| response to organic nitrogen CYP2E1;PTGS2;TRPV1 GO:0097237| OPRD1;KCNC2 GO:0001508| regulation of action potential KCND2;GLRA1;CACNA1G;KCNB1 GO:0051481| reduction of cytosolic calcium ion concentration OPRM1;KCNA5 GO:0007269| neurotransmitter secretion NAAA;SLC22A2 GO:0071333| cellular response to glucose stimulus KCNB1;SLC29A1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2C19;CYP1B1;CYP2E1;CYP1A2 GO:0009612| response to mechanical stimulus PPARG;TRPV4;KCNA5 GO:0034220| ion transmembrane transport GLRB;TRPV1;TRPA1;GLRA1;CHRNA7;GLRA3;KCNC2 GO:0055085| transmembrane transport KCNA2;CACNA1H;KCNB2;TRPV3;KCNA4;KCNC2;KCNC1;KCND2;KCNA6;TRPV2;KCNA10;KCND1;KCND3;KCNA3;CACNA1G;ABCC1;KCNC3;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;KCNA7;KCNA1;ABCG2;KCNB1;TRPM8;KCNA5;SLC22A2 GO:0001666| response to hypoxia CHRNA7;CAT;KCNA5;CYP1A1 GO:0010193| response to ozone CAT;CYP2E1 GO:0014059| regulation of dopamine secretion KCNA2;HTR2A GO:0010033| response to organic substance KCNA5;CYP1A1;PPARG;TRPA1;SOD1;PTGS2;CYP1A2 GO:0051262| protein tetramerization KCNC3;KCNC1;HMGCR;CAT GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP17A1 GO:0071456| cellular response to hypoxia SLC29A1;KCND2;PTGS2;OPRD1 GO:0042593| glucose homeostasis CNR1;KCNB1;TRPV4;PPARG GO:0051260| protein homooligomerization KCNB2;KCNA2;KCNC1;KCNA4;KCNC2;GLRA3;KCNA6;KCND2;KCNA10;KCND1;KCND3;ACAT1;KCNA3;GLRA1;KCNC3;KCNA7;KCNA1;KCNB1;KCNA5 GO:0042391| regulation of membrane potential GLRB;KCNA1;KCNA5;CACNA1G;GLRA1;CACNA1H GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1;CYP2C9 21071:[DB14011 DB08790] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways GO:0019371| cyclooxygenase pathway HPGDS;PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;HPGDS;PTGS1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;HPGDS;NAAA;GPX1;PTGS1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0001516| prostaglandin biosynthetic process PTGS1;HPGDS;PTGS2 GO:0007165| signal transduction CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18;HPGDS;CHRNA7;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS2;HPGDS;PTGS1 GO:0006631| fatty acid metabolic process ALOX15;HPGDS;PTGS1;PTGS2 GO:0007626| locomotory behavior HPGDS;SOD1;OPRM1 21072:[DB14011 DB07940] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07940|9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE BCHE common genes common pathways GO:0007612| learning PTGS2;BCHE;VDAC1 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;BCHE;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;BCHE;CYP1B1;OPRM1;PTGS2 GO:0007584| response to nutrient BCHE;PPARG;HMGCR;CNR1 21073:[DB14011 DB03935] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;FGF2;CNR2;CNR1;GPR12;HTR2A;ANXA5;HTR1A;GPR55 GO:0051781| positive regulation of cell division CAT;FGF2 GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG;FGF2 GO:0007399| nervous system development SMPD1;GLRB;FGF2 GO:0061045| negative regulation of wound healing FGF2;HMGCR GO:0001525| angiogenesis FGF2;PTGS2;CYP1B1 GO:0051209| release of sequestered calcium ion into cytosol TRPV1;TRPA1;FGF2;HTR2A GO:0010033| response to organic substance SOD1;ANXA5;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;FGF2 GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;FGF2 GO:0000187| activation of MAPK activity FGF2;SOD1;CHRNA7;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;ALOX15;CHRNA7;HMGCR;FGF2;OPRM1;HTR2A;GPR55 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ANXA5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;FGF2 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2;FGF2 GO:0002576| platelet degranulation ANXA5;SOD1 GO:0042060| wound healing OPRM1;FGF2;ALOX15 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;FGF2 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;PPARG 21074:[DB14011 DB00027] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00027|Gramicidin D ABCB1 common genes common pathways GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCB1;ABCG2;ABCC1;SMPD1;TRPA1;PPARG;CYP1A1 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;ABCB1;CACNA1I;TRPV4;VDAC1;TRPV1;TRPM8;ABCG2 GO:0006810| transport TRPV2;ABCC1;TRPV1;ABCB1;CACNA1I;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 21075:[DB14011 DB00722] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00722|Lisinopril ACE common genes common pathways GO:0002446| neutrophil mediated immunity ACE;PLA2G1B GO:0007283| spermatogenesis CNR1;SOD1;ACE GO:0001822| kidney development ACE;CAT GO:0060047| heart contraction ACE;GPX1;SOD1 GO:0050482| arachidonic acid secretion PLA2G1B;ACE GO:0008217| regulation of blood pressure PPARG;SOD1;PTGS2;ACE;PTGS1 21076:[DB14011 DB01746] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways GO:0007399| nervous system development SLC7A5;GLRB;SMPD1 GO:0006810| transport TRPV2;ABCC1;SLC7A5;ABCG2;CACNA1I;TRPV1 GO:0055085| transmembrane transport TRPV3;SLC16A10;CACNA1H;TRPV2;ABCC1;CACNA1G;TRPA1;TRPV1;VDAC1;CACNA1I;TRPV4;TRPM8;ABCG2 21077:[DB14011 DB08558] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08558|2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL lpxA;fbpC;ADRB1;LCT common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;CNR2;OPRM1;ADRB1;GPR18;PPARG GO:0002024| diet induced thermogenesis ADRB1;TRPV4;TRPV1 GO:0007165| signal transduction OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;PLA2G1B;ADRB1;CACNA1I GO:0043950| positive regulation of cAMP-mediated signaling ADRB1;OPRM1 GO:0001659| temperature homeostasis ADRB1;TRPV1;HTR2A;GPX1 GO:0008152| metabolic process LCT;SMPD1;ACAT1 GO:0009409| response to cold TRPA1;PPARG;ADRB1;TRPM8 GO:0050873| brown fat cell differentiation ADRB1;PTGS2 21078:[DB14011 DB08052] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08052|1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0042127| regulation of cell proliferation PTGS1;SRC;PTGS2 GO:0007155| cell adhesion SRC;CYP1B1 GO:0045087| innate immune response PPARG;SRC GO:0009612| response to mechanical stimulus SRC;PPARG;TRPV4 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SRC;SOD1;HMGCR;PTGS2 GO:0009615| response to virus CYP1A1;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;PPARG GO:0016236| macroautophagy VDAC1;SRC GO:0042493| response to drug SRC;CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;SRC GO:0071456| cellular response to hypoxia SLC29A1;SRC;OPRD1;PTGS2 GO:0002376| immune system process SRC;IDO1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;SRC;HTR2A;GPR55;HMGCR;OPRM1;ALOX15;TRPV4 GO:0045892| negative regulation of transcription, DNA-dependent SRC;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;SRC GO:0010628| positive regulation of gene expression TRPV4;SRC GO:0051974| negative regulation of telomerase activity SRC;PPARG GO:0035556| intracellular signal transduction PLA2G1B;SRC GO:0042542| response to hydrogen peroxide TRPA1;SOD1;CAT;GPX1;SRC GO:0043065| positive regulation of apoptotic process CNR1;SOD1;PTGS2;SRC;PPARG;SMPD1;IDO1;TRPV1;CYP1B1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;SRC;PTGS2 GO:0031667| response to nutrient levels SOD1;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;HTR2A GO:0016032| viral reproduction SRC;HTR2A;VDAC1 GO:0032869| cellular response to insulin stimulus SRC;PPARG;PLA2G1B GO:0070542| response to fatty acid CAT;SRC;PTGS2 GO:0007165| signal transduction HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;SRC;GPR18;PPARG;SMPD1;PLA2G1B;CACNA1I GO:0045453| bone resorption GPR55;SRC GO:0008283| cell proliferation GPX1;SRC;HTR1A;CYP1A1 21079:[DB14011 DB07598] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07598|2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE GRIA2 common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7;GRIA2 GO:0006811| ion transport TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;TRPA1;GLRA1;CACNA1G;CHRNA7;TRPV2;GRIA2;GLRA3;TRPV3;CACNA1H GO:0007268| synaptic transmission HTR2A;GLRA3;OPRD1;OPRM1;GRIA2;GLRA1;CACNA1G;VDAC1;GLRB GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;GLRA3;CHRNA7;GRIA2 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRA1;TRPV1;GLRB;OPRM1;GLRA3;SLC29A1;GRIA2;CHRNA7 21080:[DB14011 DB09031] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09031|Miltefosine ABCB1;PLD1 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;DAGLA;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG;PLD1;PTGS1;NAAA;GPX1;NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006654| phosphatidic acid biosynthetic process PLA2G1B;PLD1 GO:0043312| neutrophil degranulation PLD1;CAT;ALOX5 GO:0042493| response to drug CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCB1;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0006810| transport TRPV2;ABCC1;ABCG2;TRPV1;CACNA1I;ABCB1 GO:0016042| lipid catabolic process PLD1;NAPEPLD;PLA2G1B;DAGLA GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;ABCG2;TRPM8;TRPV1;VDAC1;TRPV4;ABCB1;CACNA1I;TRPA1;CACNA1G;ABCC1 21081:[DB14011 DB08429] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways GO:0046718| entry of virus into host cell HTR2A;DPP4 GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7;DPP4 GO:0007155| cell adhesion DPP4;CYP1B1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;DPP4 21082:[DB14011 DB02217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02217|Dpb-T NT5M common genes common pathways 21083:[DB14011 DB09552] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09552|Thonzonium ATP6V1C1 common genes common pathways GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;TRPV1;GLRA3;ATP6V1C1;CHRNA7 GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV4;GLRB;CACNA1I;VDAC1;TRPV1;GLRA3;ATP6V1C1;TRPV3;CACNA1H;CHRNA7;TRPV2 21084:[DB14011 DB03480] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03480|Brequinar Analog DHODH common genes common pathways GO:0042594| response to starvation PPARG;DHODH;ACAT1 GO:0055114| oxidation-reduction process CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2C19;GSR;IDO1;CYP2D6;CYP1A1;CYP2C9;CRYZ;GPX1;ALOX5;PTGS1;CAT;DHODH;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1 GO:0042493| response to drug DHODH;CAT;PTGS2;CYP1A2;HTR2A;SOD1;ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG GO:0031000| response to caffeine PPARG;DHODH GO:0043065| positive regulation of apoptotic process DHODH;SOD1;CNR1;PTGS2;IDO1;CYP1B1;TRPV1;PPARG;SMPD1 GO:0007595| lactation DHODH;SLC29A1 GO:0007565| female pregnancy DHODH;IDO1 GO:0014070| response to organic cyclic compound AANAT;ACAT1;DHODH;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 21085:[DB14011 DB04531] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04531|Benzylcysteine MGMT common genes common pathways GO:0045471| response to ethanol CAT;OPRM1;HMGCR;MGMT;SOD1;CNR1 GO:0009636| response to toxin CYP1A1;CYP1B1;MGMT;GPX1;CAT GO:0014070| response to organic cyclic compound ACAT1;AANAT;PTGS2;CYP1A2;MGMT;CYP1A1;PPARG;TRPA1 GO:0032259| methylation MGMT;CYP1A2 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;MGMT;HMGCR;PTGS2 GO:0034599| cellular response to oxidative stress GSR;MGMT;SOD1;CAT;GPX1 GO:0071407| cellular response to organic cyclic compound MGMT;CYP1B1;CYP1A1 GO:0042493| response to drug CYP1A2;PTGS2;MGMT;HTR2A;SOD1;CAT;SMPD1;ABCC1;CYP1A1;PPARG;TRPA1;ABCG2 21086:[DB14011 DB05035] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05035|Eprotirome THRA;THRB common genes common pathways GO:0007611| learning or memory THRA;CNR1;CHRNA7 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;THRB;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;THRA;PLA2G1B;THRB GO:0006355| regulation of transcription, DNA-dependent THRA;PPARG;THRB GO:0006367| transcription initiation from RNA polymerase II promoter THRB;THRA;PPARG GO:0007605| sensory perception of sound GPX1;SOD1;THRB GO:0045892| negative regulation of transcription, DNA-dependent THRA;PPARG;THRB GO:0006351| transcription, DNA-dependent THRA;PPARG;THRB GO:0043401| steroid hormone mediated signaling pathway PPARG;THRA;THRB GO:0008016| regulation of heart contraction THRA;THRB;CACNA1H GO:0006357| regulation of transcription from RNA polymerase II promoter THRB;THRA;PPARG GO:0001503| ossification THRA;ALOX15 GO:0009409| response to cold TRPM8;THRA;PPARG;TRPA1 21087:[DB14011 DB03782] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03782|N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea PLAU common genes common pathways GO:0007165| signal transduction SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;PLAU;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;GPR12;CNR1;CHRNA7 GO:0043312| neutrophil degranulation CAT;ALOX5;PLAU GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLAU GO:0001666| response to hypoxia CHRNA7;CAT;PLAU;CYP1A1 21088:[DB14011 DB01684] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01684|1-Hydroxy-1-Thio-Glycerol PREP common genes common pathways 21089:[DB14011 DB11079] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes PTGS2;PTGS1 common pathways GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;TRPA1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A;CNR1;CHRNA7 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response CNR2;PTGS2;ALOX5;PTGS1;TRPV1;IDO1;ALOX15 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9 GO:0009314| response to radiation CAT;PTGS2;OPRM1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0019233| sensory perception of pain TRPA1;TRPV1;CNR2;PTGS2;OPRM1;OPRD1;HTR2A;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance SOD1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1 GO:0098869| GSR;PTGS2;PTGS1;GPX1;CAT GO:0006979| response to oxidative stress SOD1;PTGS2;CAT;GPX1;PTGS1 GO:0097756| HMGCR;PTGS2 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0007568| aging CYP1A1;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT GO:0034605| cellular response to heat TRPV1;TRPV4;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway PTGS2;GPX1;ALOX5;ALOX15 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP2C9;CYP1A1;CRYZ GO:0042493| response to drug CAT;PTGS2;CYP1A2;SOD1;HTR2A;ABCG2;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;ALOX15 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0008284| positive regulation of cell proliferation CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process SOD1;PTGS2;HMGCR;CAT;GPX1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;IDO1;CYP1A1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning VDAC1;PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2;SOD1 21090:[DB14011 DB02300] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0007595| lactation SLC29A1;VDR GO:0019430| removal of superoxide radicals SOD1;MPO GO:0006816| calcium ion transport CACNA1H;TRPV3;CHRNA7;TRPV2;VDR;TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;TRPV1 GO:0006351| transcription, DNA-dependent VDR;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR GO:0033280| response to vitamin D PTGS2;CYP24A1 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;VDR;PPARG;CYP1B1 GO:0001649| osteoblast differentiation CYP24A1;CAT GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;CHRNA7;VDR;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2 GO:0055114| oxidation-reduction process CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;CYP24A1;CAT;MPO;ALOX5;GPX1;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR GO:0006355| regulation of transcription, DNA-dependent VDR;PPARG GO:0032094| response to food MPO;OPRM1;CYP1A1 GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;VDR GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1;MPO GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;TRPV1;TRPV4;PPARG GO:0043312| neutrophil degranulation MPO;ALOX5;CAT GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;PLA2G1B;PPARG GO:0009612| response to mechanical stimulus PPARG;TRPV4;MPO GO:0043066| negative regulation of apoptotic process GPX1;MPO;CAT;PTGS2;HMGCR;SOD1 GO:0042744| hydrogen peroxide catabolic process CAT;GPX1;MPO GO:0045892| negative regulation of transcription, DNA-dependent VDR;PPARG GO:0042359| vitamin D metabolic process CYP1A1;CYP24A1;CYP3A4 GO:0010628| positive regulation of gene expression VDR;TRPV4 GO:0046697| decidualization VDR;PTGS2 GO:0007568| aging CYP1A1;NAPEPLD;SOD1;HTR2A;CNR1;PTGS2;HMGCR;CAT;MPO GO:0006979| response to oxidative stress PTGS2;SOD1;MPO;PTGS1;GPX1;CAT GO:0006874| cellular calcium ion homeostasis VDR;CHRNA7;GPR12;HTR2A;TRPV4;TRPM8 21091:[DB14011 DB08437] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways GO:0008283| cell proliferation CYP1A1;GPX1;HTR1A;RPL23A GO:0045471| response to ethanol RPL15;CNR1;SOD1;OPRM1;HMGCR;CAT GO:0007283| spermatogenesis RPL10L;CNR1;SOD1 GO:0010628| positive regulation of gene expression RPL11;RPL23;TRPV4 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;RPL23 GO:0008284| positive regulation of cell proliferation RPL23;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;RPL23;PPARG 21092:[DB14011 DB03137] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03137|8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0009409| response to cold TRPM8;PPARG;HSP90AA1;TRPA1 GO:0007165| signal transduction SMPD1;GPR18;PPARG;HSP90AA1;CACNA1I;PLA2G1B;OPRD1;CNR2;OPRM1;GPR12;CNR1;HTR2A;HTR1A;GPR55;CHRNA7 GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0043312| neutrophil degranulation CAT;ALOX5;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;OPRM1;PTGS2 21093:[DB14011 DB08313] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08313|nocodazole HPGDS common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;HPGDS;GPX1;NAAA;PTGS1;CYP2C9;PPARG;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA GO:0006693| prostaglandin metabolic process HPGDS;PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway HPGDS;PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process HPGDS;PTGS1;PTGS2;PLA2G1B GO:0007165| signal transduction HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7;HPGDS;PPARG;GPR18;SMPD1;CACNA1I;PLA2G1B GO:0001516| prostaglandin biosynthetic process HPGDS;PTGS1;PTGS2 GO:0007626| locomotory behavior SOD1;OPRM1;HPGDS GO:0006631| fatty acid metabolic process ALOX15;PTGS2;HPGDS;PTGS1 21094:[DB14011 DB04752] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways GO:0006351| transcription, DNA-dependent NR5A1;PPARG GO:0043401| steroid hormone mediated signaling pathway NR5A1;PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter NR5A1;PPARG GO:0010628| positive regulation of gene expression TRPV4;NR5A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;NR5A1 GO:0006355| regulation of transcription, DNA-dependent NR5A1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;NR5A1 GO:0006367| transcription initiation from RNA polymerase II promoter NR5A1;PPARG 21095:[DB14011 DB12747] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB12747|Tertomotide TERT common genes common pathways GO:0045766| positive regulation of angiogenesis CYP1B1;CHRNA7;TERT GO:0046686| response to cadmium ion TERT;CAT GO:0071456| cellular response to hypoxia PTGS2;TERT;OPRD1;SLC29A1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;TERT;HMGCR;PTGS2 GO:1900087| TERT;CYP1A1 GO:0043524| negative regulation of neuron apoptosis SOD1;TERT GO:0010629| negative regulation of gene expression TERT;OPRD1 21096:[DB14011 DB13170] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13170|Plecanatide GUCY1A2 common genes common pathways GO:0007165| signal transduction CACNA1I;PLA2G1B;PPARG;GUCY1A2;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0035556| intracellular signal transduction PLA2G1B;GUCY1A2 21097:[DB14011 DB05307] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05307|CHF-1512 DDC common genes common pathways GO:0033076| isoquinoline alkaloid metabolic process DDC;CYP2D6 GO:0009636| response to toxin GPX1;CAT;DDC;CYP1B1;CYP1A1 GO:0071312| cellular response to alkaloid DDC;TRPV1 GO:0046219| indolalkylamine biosynthetic process DDC;AANAT GO:0071363| cellular response to growth factor stimulus TRPV1;DDC;CAT;OPRD1 GO:0007623| circadian rhythm DDC;AANAT 21098:[DB14011 DB01073] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes SLC29A1 common pathways GO:1901642| SLC28A3;SLC29A1 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2;OPRD1 GO:0071333| cellular response to glucose stimulus SLC29A1 GO:0060079| regulation of excitatory postsynaptic membrane potential GLRB;TRPV1;GLRA1;SLC29A1;CHRNA7;OPRM1;GLRA3 GO:0055114| oxidation-reduction process CRYZ;CYP2C9;CYP1A1;GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;RRM1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7;CAT;PTGS1;ALOX5;GPX1 GO:0015949| nucleobase-containing small molecule interconversion RRM1;GSR GO:0006139| nucleobase-containing compound metabolic process SLC29A1;DCK GO:0008283| cell proliferation GPX1;HTR1A;POLA1;CYP1A1 GO:0030431| sleep HTR2A;SLC29A1;CACNA1I GO:0015862| uridine transport SLC29A1 GO:0008152| metabolic process ACAT1;RRM1;SMPD1 GO:0007595| lactation SLC29A1 GO:0016032| viral reproduction HTR2A;POLA1;VDAC1 GO:0015858| nucleoside transport SLC29A1 21099:[DB14011 DB00436] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways GO:0032259| methylation TPMT;CYP1A2 GO:0001822| kidney development CAT;CA2 GO:0035722| interleukin-12-mediated signaling pathway CA1;SOD1 GO:0034465| response to carbon monoxide SOD1;KCNMA1 GO:0042391| regulation of membrane potential CACNA1H;KCNMA1;GLRB;CACNA1G;GLRA1 GO:0006810| transport SLC12A3;TRPV2;ABCG2;TRPV1;CACNA1I;ABCC1 GO:0001666| response to hypoxia CHRNA7;CAT;KCNMA1;CYP1A1 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;CA2;SOD1;PTGS2;CYP1A2 GO:0055085| transmembrane transport CACNA1H;TRPV3;KCNMA1;TRPV2;SLC12A3;CACNA1G;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8 GO:0043065| positive regulation of apoptotic process SOD1;CNR1;KCNMA1;PTGS2;PPARG;SMPD1;IDO1;CYP1B1;TRPV1 GO:0006970| response to osmotic stress TRPV4;KCNMA1 GO:0051592| response to calcium ion AANAT;KCNMA1 GO:0035725| sodium ion transmembrane transport CACNA1I;CACNA1G;SLC12A3;CACNA1H GO:1902476| GLRA3;SLC12A3;GLRA1;GLRB GO:0009268| response to pH TRPV1;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;CACNA1H;KCNMA1 GO:0060083| smooth muscle contraction involved in micturition KCNMA1;TRPV1 GO:0010043| response to zinc ion CA2;AANAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0006139| nucleobase-containing compound metabolic process SLC29A1;TPMT GO:0006811| ion transport TRPV3;CACNA1H;GLRA3;KCNMA1;SLC12A3;TRPV2;CHRNA7;CACNA1G;TRPA1;GLRA1;VDAC1;TRPV4;GLRB;CACNA1I;TRPV1;TRPM8 21100:[DB14011 DB03983] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;PTGS1;GPX1;CAT;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;GSR;IDO1;SUOX;CYP2C19;ALOX15;CYP3A5;CYP17A1 21101:[DB14011 DB00092] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways GO:0007155| cell adhesion CD2;CYP1B1 GO:0045087| innate immune response C1QA;C1QC;FCGR1A;PPARG;C1QB;C1R GO:0043312| neutrophil degranulation CAT;ALOX5;FCGR3B;FCGR2A GO:0046330| positive regulation of JNK cascade FCGR2B;TRPV4 GO:0002376| immune system process C1R;C1QB;IDO1;FCGR2A;FCGR1A;C1QC;C1QA GO:0006915| apoptotic process VDAC1;GPX1;CD2 GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;CD2 GO:0006954| inflammatory response CNR2;PTGS2;PTGS1;ALOX5;FCGR2B;TRPV1;ALOX15;IDO1 GO:0016032| viral reproduction HTR2A;FCGR2B;VDAC1 GO:0006955| immune response C1QC;FCGR2C;OPRD1;FCGR3A;CNR2;FCGR1A;FCGR3B;FCGR2B;C1R GO:0032693| negative regulation of interleukin-10 production FCGR2B;IDO1 GO:0007165| signal transduction SMPD1;FCGR2B;PPARG;GPR18;CACNA1I;PLA2G1B;FCGR1A;CNR2;OPRM1;FCGR2C;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7 21102:[DB14011 DB07317] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07317|(3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one HSP90AA1 common genes common pathways GO:0046677| response to antibiotic CYP1A1;HSP90AA1;SOD1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AA1;TRPV1;OPRM1;PTGS2 GO:0009409| response to cold TRPA1;PPARG;HSP90AA1;TRPM8 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0007165| signal transduction CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;PLA2G1B;CACNA1I;SMPD1;PPARG;HSP90AA1;GPR18 21103:[DB14011 DB07974] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07974|1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 21104:[DB14011 DB13983] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0001662| behavioral fear response HTR1A;GABRA5;VDAC1 GO:0009791| post-embryonic development GABRG2;CYP1A2 GO:0006811| ion transport TRPV3;GABRG2;CACNA1H;GLRA3;GABRA1;GABRA6;GABRA4;TRPV2;CHRNA7;GABRG3;GABRA5;GABRA3;GABRG1;CACNA1G;TRPA1;GLRA1;TRPV1;TRPV4;CACNA1I;GLRB;VDAC1;TRPM8;GABRA2 GO:0007165| signal transduction PPARG;GPR18;GABRA5;SMPD1;PLA2G1B;CACNA1I;HTR1A;GABRA6;GPR55;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1;CHRNA7 GO:0007420| brain development GABRA5;ACAT1 GO:0006821| chloride transport GLRB;GABRA2;GABRG1;GABRA5;GABRA3;GLRA1;GABRG3;GABRG2;GABRA6;GABRA4;GLRA3;GABRA1 GO:1902476| GLRA1;GABRG1;GABRA5;GABRA3;GABRA2;GLRB;GABRA6;GABRA4;GLRA3;GABRA1;GABRG2;GABRG3 GO:0007268| synaptic transmission GLRA3;HTR2A;OPRD1;GABRG2;OPRM1;VDAC1;GLRB;GLRA1;GABRA5;CACNA1G;GABRG1 GO:0043524| negative regulation of neuron apoptosis GABRA5;SOD1 GO:0060078| regulation of postsynaptic membrane potential CHRNA7;GABRA1 GO:0034220| ion transmembrane transport TRPV1;GLRB;GABRA2;GABRA5;GABRA3;GABRG1;GLRA1;TRPA1;CHRNA7;GABRG3;GABRG2;GLRA3;GABRA1;GABRA6;GABRA4 GO:0007605| sensory perception of sound SOD1;GPX1;GABRA5 GO:0006810| transport GABRG2;GABRA4;GABRA6;GABRA1;TRPV2;ABCC1;GABRA3;GABRA5;CACNA1I;TRPV1;ABCG2 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1;CAT;GABRG3;HTR2A;SOD1;PTGS2;CYP1A2 GO:0043523| regulation of neuron apoptosis GPX1;GABRA5 21105:[DB14011 DB08383] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;CNR1;GPR12;HTR2A;PDE10A GO:0008152| metabolic process ACAT1;PDE10A;SMPD1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;PDE10A;CHRNA7;GPR55;HTR1A;HTR2A;CNR1;GPR12;OPRM1;CNR2;OPRD1 21106:[DB14011 DB02602] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02602|AL7182 CA2 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;CA2;CYP1A1;PPARG;TRPA1 GO:0001822| kidney development CA2;CAT GO:0043627| response to estrogen stimulus CA2;PPARG GO:0010043| response to zinc ion CA2;AANAT GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0009268| response to pH CA2;TRPV1 21107:[DB14011 DB02895] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes GSR common pathways GO:0015949| nucleobase-containing small molecule interconversion GSR GO:0006749| glutathione metabolic process GSR;GPX1;SOD1 GO:0045454| cell redox homeostasis GSR;GPX1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0034599| cellular response to oxidative stress SOD1;GPX1;CAT;GSR GO:0098869| GSR;PTGS2;GPX1;PTGS1;CAT 21108:[DB14011 DB06766] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06766|Alcaftadine HRH1 common genes common pathways GO:0007613| memory CHRNA7;CNR1;HTR2A;PTGS2;HRH1 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1;CHRNA7;GPR55;HTR1A;GPR12;CNR1;HTR2A;OPRM1;CNR2;OPRD1;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A GO:0008542| visual learning HMGCR;HRH1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2;CNR2;HRH1;TRPV1;ALOX15;IDO1 GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;HRH1;OPRM1;CNR2 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;HRH1;OPRD1;OPRM1 21109:[DB14011 DB07279] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07279|N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE F2 common genes common pathways GO:0061844| F2;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;F2;TRPA1 GO:0001934| positive regulation of protein phosphorylation F2;CHRNA7 GO:0010468| regulation of gene expression F2;CYP1A2 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;F2 GO:0007186| G-protein coupled receptor signaling pathway HTR2A;CNR1;GPR12;GPR55;HTR1A;OPRD1;OPRM1;CNR2;F2;GPR18;PPARG GO:0009611| response to wounding GPX1;F2;CYP1A1 GO:0008284| positive regulation of cell proliferation F2;PTGS2;HMGCR;HTR1A;HTR2A;CHRNA7 21110:[DB14011 DB02967] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02967|N-Ethylmaleimide CLC common genes common pathways GO:0046006| regulation of activated T cell proliferation CLC;IDO1 21111:[DB14011 DB07147] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07147|methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate ADAM17 common genes common pathways GO:0050830| defense response to Gram-positive bacterium ADAM17;PLA2G1B GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;ADAM17;PPARG;ABCC1;SMPD1;ABCG2 GO:0007155| cell adhesion ADAM17;CYP1B1 GO:0008284| positive regulation of cell proliferation ADAM17;HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;CYP1A1;ADAM17;IDO1 GO:0001666| response to hypoxia ADAM17;CYP1A1;CAT;CHRNA7 GO:0002446| neutrophil mediated immunity PLA2G1B;ADAM17 GO:0001934| positive regulation of protein phosphorylation CHRNA7;ADAM17 21112:[DB14011 DB00484] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0007565| female pregnancy IDO1;ADRA2B;ADRA2C GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;ADRA2A GO:0050796| regulation of insulin secretion ADRA2A;ADRA2C;CNR1 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA2C;HTR2A GO:0001819| positive regulation of cytokine production SOD1;ADRA2A GO:0032870| cellular response to hormone stimulus CACNA1H;ADRA2A GO:0007165| signal transduction SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B;ADRA2A;CNR2;OPRM1;OPRD1;ADRA2C;HTR1A;GPR55;HTR2A;CNR1;GPR12;ADRA2B;CHRNA7 GO:0051930| regulation of sensory perception of pain ADRA2C;OPRM1;OPRD1 GO:0045777| positive regulation of blood pressure CNR1;ADRA2B GO:0030818| negative regulation of cAMP biosynthetic process OPRM1;ADRA2A GO:0061179| negative regulation of insulin secretion involved in cellular response to glucose stimulus HMGCR;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA2A;HTR1A;HTR2A;PTGS2;HMGCR;CHRNA7 GO:0022900| electron transport chain GSR;IDO1;AOX1;CYP1A2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;AOX1;CRYZ;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0007186| G-protein coupled receptor signaling pathway ADRA2A;GPR18;PPARG;ADRA2B;HTR2A;GPR12;CNR1;GPR55;HTR1A;ADRA2C;OPRD1;OPRM1;CNR2 GO:0042593| glucose homeostasis TRPV4;ADRA2A;PPARG;CNR1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;AOX1;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0000187| activation of MAPK activity SOD1;ADRA2B;CHRNA7;PLA2G1B GO:0043406| positive regulation of MAP kinase activity ADRA2A;HTR2A 21113:[DB14011 DB08599] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08599|N-[(4-methoxyphenyl)sulfonyl]-D-alanine MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter MMP12;PPARG;TRPV1;TRPV4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;PPARG;PLA2G1B GO:0042060| wound healing OPRM1;MMP12;ALOX15 GO:0010628| positive regulation of gene expression MMP12;TRPV4 21114:[DB14011 DB05207] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0000187| activation of MAPK activity SOD1;CHRNA7;TNF;PLA2G1B GO:0070374| positive regulation of ERK1 and ERK2 cascade HMGCR;OPRM1;HTR2A;GPR55;CHRNA7;TNF;TRPV4;ALOX15 GO:0010033| response to organic substance PPARG;CYP1A1;TRPA1;TNF;PTGS2;CYP1A2;SOD1 GO:0045892| negative regulation of transcription, DNA-dependent TNF;PPARG GO:0043406| positive regulation of MAP kinase activity HTR2A;TNF GO:0010628| positive regulation of gene expression TNF;TRPV4 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;TRPV1;TNF GO:0071407| cellular response to organic cyclic compound CYP1B1;TNF;CYP1A1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;PPARG GO:0050830| defense response to Gram-positive bacterium TNF;PLA2G1B GO:0051897| positive regulation of protein kinase B signaling cascade TNF;GPX1 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;HMGCR;PTGS2 GO:0046330| positive regulation of JNK cascade TNF;TRPV4 GO:0071230| cellular response to amino acid stimulus GLRA1;TNF GO:0042127| regulation of cell proliferation PTGS1;PTGS2;TNF GO:0000122| negative regulation of transcription from RNA polymerase II promoter TNF;PPARG;TRPV4;TRPV1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;PPARG;PLA2G1B GO:0009615| response to virus CYP1A1;TNF GO:0006919| activation of caspase activity TNF;PPARG GO:0050796| regulation of insulin secretion CNR1;TNF GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2;OPRD1 GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;CNR1;GPR12;HTR2A;GPR55;HTR1A;IL1R1;CACNA1I;PLA2G1B;SMPD1;GPR18;PPARG GO:0034116| positive regulation of heterotypic cell-cell adhesion ALOX15;TNF GO:0001819| positive regulation of cytokine production TNF;SOD1 GO:0001934| positive regulation of protein phosphorylation TNF;CHRNA7 GO:0010629| negative regulation of gene expression TNF;OPRD1 GO:0006955| immune response OPRD1;CNR2;IL1R1;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;PLA2G1B;CAT GO:0006954| inflammatory response ALOX5;PTGS1;CNR2;PTGS2;TRPV1;IDO1;ALOX15;TNF GO:0000060| protein import into nucleus, translocation TNF;OPRD1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;TRPV1;IL1R1 GO:0031622| positive regulation of fever generation PTGS2;CNR1;TNF GO:2000377| regulation of reactive oxygen species metabolic process TNF;CYP1B1 GO:0043065| positive regulation of apoptotic process PPARG;TNF;SMPD1;IDO1;TRPV1;CYP1B1;CNR1;SOD1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;IL1R1;TNF 21115:[DB14011 DB06677] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06677|Clazosentan EDNRA common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12;EDNRA;PPARG;GPR18 GO:0015758| glucose transport EDNRA;PLA2G1B GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1;EDNRA GO:0007202| activation of phospholipase C activity GPR55;HTR2A;EDNRA GO:0014824| artery smooth muscle contraction EDNRA;HTR2A GO:0007165| signal transduction PPARG;EDNRA;GPR18;SMPD1;PLA2G1B;CACNA1I;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0006939| smooth muscle contraction EDNRA;HTR2A GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;TRPV1;TRPV4;EDNRA GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRM1;OPRD1;EDNRA GO:0008217| regulation of blood pressure PPARG;EDNRA;SOD1;PTGS2;PTGS1 GO:0008283| cell proliferation CYP1A1;EDNRA;HTR1A;GPX1 GO:0007507| heart development PPARG;EDNRA GO:0042310| vasoconstriction HTR1A;EDNRA 21116:[DB14011 DB07223] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07223|METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE CTSB common genes common pathways GO:0046718| entry of virus into host cell CTSB;HTR2A GO:0043312| neutrophil degranulation CTSB;ALOX5;CAT GO:0030855| epithelial cell differentiation CTSB;VDAC1;PPARG GO:0046697| decidualization PTGS2;CTSB 21117:[DB14011 DB04258] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04258|Seocalcitol VDR common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;VDR;CHRNA7;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;VDR;PPARG;CYP1B1 GO:0006351| transcription, DNA-dependent PPARG;VDR GO:0043401| steroid hormone mediated signaling pathway PPARG;VDR GO:0007595| lactation SLC29A1;VDR GO:0006816| calcium ion transport TRPA1;CACNA1G;TRPM8;TRPV1;TRPV4;CACNA1I;TRPV3;CACNA1H;CHRNA7;VDR;TRPV2 GO:0046697| decidualization PTGS2;VDR GO:0006874| cellular calcium ion homeostasis HTR2A;GPR12;VDR;CHRNA7;TRPV4;TRPM8 GO:0045892| negative regulation of transcription, DNA-dependent PPARG;VDR GO:0010628| positive regulation of gene expression TRPV4;VDR GO:0000122| negative regulation of transcription from RNA polymerase II promoter VDR;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;VDR GO:0006355| regulation of transcription, DNA-dependent PPARG;VDR GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;VDR 21118:[DB14011 DB01188] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0086002| ATP1A1;CACNA1G GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;TRPV1;GLRA3;ATP1A1;CHRNA7 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;CYP1A2;PTGS2;ATP1A1;SOD1;HTR2A;CAT GO:0006811| ion transport TRPM8;VDAC1;TRPV4;CACNA1I;GLRB;TRPV1;GLRA1;TRPA1;CACNA1G;CHRNA7;TRPV2;GLRA3;ATP1A1;TRPV3;CACNA1H GO:0008217| regulation of blood pressure PTGS2;SOD1;ATP1A1;PTGS1;PPARG GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 21119:[DB14011 DB08476] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08476|3-AMINO-AZACYCLOTRIDECAN-2-ONE MMP8 common genes common pathways GO:0043312| neutrophil degranulation ALOX5;MMP8;CAT 21120:[DB14011 DB11221] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11221|Dioxybenzone SHBG common genes common pathways 21121:[DB14011 DB06548] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0006694| steroid biosynthetic process FDPS;HMGCR;CYP17A1 GO:0006695| cholesterol biosynthetic process FDPS;HMGCR;GGPS1 GO:0008203| cholesterol metabolic process HMGCR;CAT;FDPS GO:0008299| isoprenoid biosynthetic process HMGCR;FDPS;GGPS1 GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP3A4;FDPS;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5 GO:0016032| viral reproduction FDPS;HTR2A;VDAC1 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;FDPS;PTGS1;NAAA;GPX1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0016126| sterol biosynthetic process HMGCR;FDPS 21122:[DB14011 DB11098] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways GO:0006821| chloride transport GLRA1;GLRB;GLRA3;SLC12A2 GO:0006811| ion transport CACNA1G;GLRA1;TRPA1;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;TRPM8;TRPV3;SLC12A2;CACNA1H;GLRA3;TRPV2;CHRNA7;SLC12A1 GO:1902476| GLRA1;GLRB;GLRA3;SLC12A2;SLC12A1 GO:0007568| aging CAT;HMGCR;PTGS2;SLC12A2;CNR1;SOD1;HTR2A;NAPEPLD;CYP1A1 GO:0006810| transport ABCC1;ABCG2;CACNA1I;TRPV1;SLC12A2;SLC12A1;TRPV2 GO:0034220| ion transmembrane transport GLRA1;TRPA1;GLRB;TRPV1;GLRA3;SLC12A1;CHRNA7 GO:0055085| transmembrane transport SLC12A1;TRPV2;TRPV3;CACNA1H;SLC12A2;TRPM8;ABCG2;TRPV1;TRPV4;CACNA1I;VDAC1;TRPA1;ABCC1;CACNA1G 21123:[DB14011 DB00045] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00045|Lyme disease vaccine (recombinant OspA) TLR2 common genes common pathways GO:0006691| leukotriene metabolic process ALOX15;TLR2;ABCC1;ALOX5 GO:0050830| defense response to Gram-positive bacterium TLR2;PLA2G1B GO:0007612| learning TLR2;VDAC1;PTGS2 GO:0032496| response to lipopolysaccharide IDO1;TLR2;CYP1A1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0045087| innate immune response PPARG;TLR2 GO:0043312| neutrophil degranulation CAT;ALOX5;TLR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TLR2 GO:0006915| apoptotic process VDAC1;TLR2;GPX1 GO:0048714| positive regulation of oligodendrocyte differentiation TLR2;PPARG GO:0001666| response to hypoxia CAT;CHRNA7;TLR2;CYP1A1 GO:0010628| positive regulation of gene expression TRPV4;TLR2 GO:0032735| positive regulation of interleukin-12 production TLR2;IDO1 GO:0002376| immune system process TLR2;IDO1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;TLR2 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2;CNR2;TRPV1;ALOX15;IDO1;TLR2 GO:0006955| immune response TLR2;OPRD1;CNR2 GO:0001774| microglial cell activation TLR2;TRPV1 GO:0032868| response to insulin stimulus AANAT;CAT;TLR2;TRPV4 GO:0009636| response to toxin GPX1;CAT;TLR2;CYP1A1;CYP1B1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;TLR2;PPARG GO:0050729| positive regulation of inflammatory response TLR2;TRPV4 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;GPR55;HTR1A;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;TLR2;GPR18 GO:0070542| response to fatty acid PTGS2;CAT;TLR2 21124:[DB14011 DB02492] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02492|Ghavamiol MAN2A1 common genes common pathways GO:0008152| metabolic process SMPD1;MAN2A1;ACAT1 GO:0001889| liver development ACAT1;CYP1A1;MAN2A1 GO:0050769| positive regulation of neurogenesis MAN2A1;OPRM1 21125:[DB14011 DB01944] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01944|(S)-blebbistatin MYH14 common genes common pathways GO:0007605| sensory perception of sound MYH14;GPX1;SOD1 GO:0019228| regulation of action potential in neuron MYH14;CACNA1I;CACNA1G;CACNA1H 21126:[DB14011 DB04372] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 21127:[DB14011 DB00905] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0007165| signal transduction CHRNA7;PTGFR;HTR1A;GPR55;HTR2A;CNR1;GPR12;PTGER1;CNR2;OPRM1;OPRD1;PTGER3;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0001523| retinoid metabolic process NAPEPLD;AKR1C3 GO:0071276| cellular response to cadmium ion AKR1C3;CYP1A2;SOD1 GO:0007584| response to nutrient CNR1;AKR1C3;HMGCR;PPARG GO:0006693| prostaglandin metabolic process PTGS2;AKR1C3;PTGS1 GO:0042572| retinol metabolic process CYP1B1;AKR1C3 GO:0000060| protein import into nucleus, translocation AKR1C3;OPRD1 GO:0071277| cellular response to calcium ion AKR1C3;ALOX15 GO:0031622| positive regulation of fever generation PTGER3;PTGS2;CNR1 GO:0042448| progesterone metabolic process AKR1C3;CYP17A1 GO:0010942| positive regulation of cell death AKR1C3;PTGS2 GO:0071379| cellular response to prostaglandin stimulus PPARG;AKR1C3 GO:0019371| cyclooxygenase pathway AKR1C3;PTGS2;PTGS1 GO:0042574| retinal metabolic process AKR1C3;CYP1B1 GO:0008202| steroid metabolic process AKR1C3;HMGCR;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP17A1;CYP2C9;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2;CAT;PTGFR GO:0007186| G-protein coupled receptor signaling pathway GPR18;PPARG;CNR1;GPR12;HTR2A;HTR1A;GPR55;AKR1C3;OPRD1;PTGER3;PTGER1;CNR2;OPRM1;PTGFR GO:0010628| positive regulation of gene expression PTGFR;TRPV4 GO:0008219| cell death HTR2A;PTGER3 GO:0043066| negative regulation of apoptotic process GPX1;PTGFR;CAT;PTGS2;HMGCR;SOD1 GO:0008284| positive regulation of cell proliferation HMGCR;AKR1C3;PTGS2;HTR2A;HTR1A;PTGFR;CHRNA7 GO:0032496| response to lipopolysaccharide PTGFR;CYP1A2;OPRM1;PTGS2;CNR2;PTGER1;CNR1;IDO1;CYP1A1 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger OPRM1;OPRD1;PTGER3;HTR2A GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;AKR1C3 GO:0055114| oxidation-reduction process CAT;ALOX5;PTGS1;GPX1;SOD1;CYP3A4;HMGCR;AKR1C3;CYP1A2;PTGS2;CYP3A7;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1 21128:[DB14011 DB00466] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes CYP1A1;GLRA3;GLRA1 common pathways GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP17A1;CYP1B1;CYP3A4;HMGCR;CYP1A2;CYP3A7 GO:0009611| response to wounding GPX1;CYP1A1 GO:0007568| aging CAT;SOD1;HTR2A;CNR1;NAPEPLD;HMGCR;PTGS2;CYP1A1 GO:0006810| transport ABCG2;TRPV1;CACNA1I;ABCC1;TRPV2;GABRA1;GABRR1 GO:0006936| muscle contraction CACNA1H;GLRA1 GO:0010041| response to iron(III) ion CYP1A1 GO:0042391| regulation of membrane potential GLRB;GLRA1;CACNA1G;CACNA1H GO:0051260| protein homooligomerization GLRA1;ACAT1;GLRA3;GLUL GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0006820| anion transport GLRA1;VDAC1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP3A5;CYP1A1 GO:0034220| ion transmembrane transport GLRA1;TRPA1;TRPV1;GLRB;GABRA1;GLRA3;GABRR1;CHRNA7;GLRA2 GO:0043200| response to amino acid stimulus GLRA3;GLRB GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1A1;CYP1B1;CYP1A2 GO:0002087| regulation of respiratory gaseous exchange by neurological system process GLRA1 GO:0001666| response to hypoxia CHRNA7;CAT;CYP1A1 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0010033| response to organic substance SOD1;CYP1A2;PTGS2;TRPA1;PPARG;CYP1A1 GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:0060080| regulation of inhibitory postsynaptic membrane potential GLRA1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;IDO1;CYP1A1 GO:0001508| regulation of action potential CACNA1G;GLRA1 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0009812| flavonoid metabolic process CYP1A1 GO:0071230| cellular response to amino acid stimulus GLRA2;GLRA1 GO:0060079| regulation of excitatory postsynaptic membrane potential CHRNA7;GLRA2;SLC29A1;GLRA3;OPRM1;GLRB;TRPV1;GLRA1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0046677| response to antibiotic CYP1A1;SOD1 GO:0009615| response to virus CYP1A1 GO:0007340| acrosome reaction GLRB;GLRA1 GO:0007218| neuropeptide signaling pathway GLRB;GLRA1;GLRA2;GLRA3;OPRM1;OPRD1 GO:0035902| response to immobilization stress CYP1A1;PPARG;CYP1A2 GO:0007628| adult walking behavior GLRA1;GLRB GO:0051970| negative regulation of transmission of nerve impulse GLRA1 GO:0071407| cellular response to organic cyclic compound CYP1A1;CYP1B1 GO:0032094| response to food CYP1A1;OPRM1 GO:0042493| response to drug TRPA1;PPARG;CYP1A1;ABCC1;SMPD1;ABCG2;HTR2A;SOD1;PTGS2;CYP1A2;CAT GO:0050905| neuromuscular process GLRA1;GLRB GO:0046685| response to arsenic-containing substance CYP1A1 GO:0055114| oxidation-reduction process GSR;IDO1;CYP2C19;CYP2D6;ALOX15;CYP3A5;CYP17A1;CYP1B1;CRYZ;CYP2C9;CYP1A1;CAT;ALOX5;GPX1;PTGS1;SOD1;CYP3A4;HMGCR;CYP1A2;PTGS2;CYP3A7 GO:0050884| neuromuscular process controlling posture GLRA1 GO:0009308| amine metabolic process CYP1A1 GO:0055093| response to hyperoxia CAT;CYP1A1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0033189| response to vitamin A CYP1A1;PPARG;CAT GO:0019216| regulation of lipid metabolic process HMGCR;CNR1;CYP1A1;PPARG GO:0060012| synaptic transmission, glycinergic GLRA3;GLRA2;GLRA1;GLRB GO:1900087| CYP1A1 GO:0007601| visual perception CRYZ;GLRA1;CYP1B1;GLRB GO:0032502| developmental process CYP1A1 GO:0043576| regulation of respiratory gaseous exchange GLRA1 GO:0043010| camera-type eye development CYP1A1 GO:0006821| chloride transport GLRB;GLRA1;GLRA2;GLRA3;GABRA1;GABRR1 GO:0097267| CYP1A2;CYP2C9;CYP1A1;CYP1B1;CYP2C19 GO:2000344| positive regulation of acrosome reaction GLRA1;CACNA1H GO:0014070| response to organic cyclic compound AANAT;ACAT1;PTGS2;CYP1A2;CYP1A1;PPARG;TRPA1 GO:0009636| response to toxin GPX1;CAT;CYP1A1;CYP1B1 GO:0006811| ion transport TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;GLRA1;TRPA1;CACNA1G;GLRA2;CHRNA7;TRPV2;GABRR1;GLRA3;GABRA1;CACNA1H;TRPV3 GO:0008283| cell proliferation GLUL;HTR1A;GPX1;CYP1A1 GO:0009624| response to nematode CYP1A1 GO:0051291| protein heterooligomerization GLRA1;GLRB GO:0017143| insecticide metabolic process CYP1A1 GO:0070365| hepatocyte differentiation CYP1A1 GO:0009692| ethylene metabolic process CYP1A1 GO:0071294| cellular response to zinc ion GLRA2;GLRA1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0019341| dibenzo-p-dioxin catabolic process CYP1A1 GO:0001889| liver development ACAT1;CYP1A1 GO:0070988| demethylation CYP1A1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0042904| 9-cis-retinoic acid biosynthetic process CYP1A1 GO:0060078| regulation of postsynaptic membrane potential GABRA1;CHRNA7 GO:0071361| cellular response to ethanol GLRA1;GLRA2 GO:0097305| GLRA1 GO:0009635| response to herbicide CYP1A1 GO:0007268| synaptic transmission OPRD1;OPRM1;HTR2A;GLRA3;GABRR1;GLRA2;CACNA1G;GLRA1;VDAC1;GLRB GO:0001964| startle response GLRB;GLRA1 GO:0060013| righting reflex GLRB;GLRA1 GO:0060137| maternal process involved in parturition CYP1A1 GO:0048565| digestive tract development CYP1A1 GO:1902476| GABRA1;GLRA3;GABRR1;GLRA2;GLRA1;GLRB 21129:[DB14011 DB01078] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01078|Deslanoside ATP1A1 common genes common pathways GO:0042493| response to drug ABCC1;SMPD1;CYP1A1;PPARG;TRPA1;ABCG2;PTGS2;CYP1A2;ATP1A1;HTR2A;SOD1;CAT GO:0086002| ATP1A1;CACNA1G GO:0034220| ion transmembrane transport CHRNA7;ATP1A1;GLRA3;TRPV1;GLRB;GLRA1;TRPA1 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0006811| ion transport GLRA1;TRPA1;CACNA1G;TRPM8;TRPV1;GLRB;TRPV4;CACNA1I;VDAC1;ATP1A1;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0008217| regulation of blood pressure SOD1;ATP1A1;PTGS2;PTGS1;PPARG 21130:[DB14011 DB09139] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB09139|Technetium Tc-99m oxidronate ALB common genes common pathways GO:0098869| ALB;GSR;PTGS2;CAT;PTGS1;GPX1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;HMGCR;PTGS2;SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0001895| retina homeostasis SOD1;ALB 21131:[DB14011 DB11945] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11945|Avelumab CD274 common genes common pathways GO:0042130| negative regulation of T cell proliferation IDO1;CD274 GO:0034097| response to cytokine stimulus CD274;PTGS2;AANAT GO:0007165| signal transduction CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;CHRNA7;GPR18;PPARG;CD274;SMPD1;PLA2G1B;CACNA1I GO:0046006| regulation of activated T cell proliferation IDO1;CD274 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CD274;TRPV1 GO:0032693| negative regulation of interleukin-10 production IDO1;CD274 GO:0006955| immune response CNR2;OPRD1;CD274 21132:[DB14011 DB01786] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01786|D-Alanine SLC16A10 common genes common pathways GO:0055085| transmembrane transport TRPV2;CACNA1H;TRPV3;SLC16A10;TRPV1;CACNA1I;TRPV4;VDAC1;ABCG2;TRPM8;CACNA1G;ABCC1;TRPA1 21133:[DB14011 DB04451] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;PPARG;CYP1A1;CTSV GO:0051384| response to glucocorticoid stimulus CTSV;PTGS2 GO:0007283| spermatogenesis SOD1;CNR1;CTSV GO:0046697| decidualization PTGS2;CTSV 21134:[DB14011 DB02101] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02101|(S,R)-fidarestat AKR1B1 common genes common pathways GO:0060135| maternal process involved in female pregnancy AKR1B1;CNR1 GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;AKR1B1 GO:0022900| electron transport chain IDO1;GSR;AKR1B1;CYP1A2 GO:0046427| positive regulation of JAK-STAT cascade AKR1B1;CYP1B1 GO:0055114| oxidation-reduction process CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;GPX1;ALOX5;PTGS1;CYP2C9;CYP1A1;AKR1B1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;HMGCR;PTGS2 GO:0010033| response to organic substance TRPA1;AKR1B1;CYP1A1;PPARG;PTGS2;CYP1A2;SOD1 21135:[DB14011 DB01225] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;F10 GO:0032094| response to food MPO;OPRM1;CYP1A1 GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP1A1;CYP2C9;MPO;GPX1;ALOX5;PTGS1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4 GO:0009612| response to mechanical stimulus MPO;TRPV4;PPARG GO:0043066| negative regulation of apoptotic process CAT;GPX1;MPO;SOD1;PTGS2;HMGCR GO:0043312| neutrophil degranulation CAT;ALOX5;MPO GO:0032496| response to lipopolysaccharide OPRM1;CYP1A2;CNR2;PTGS2;CNR1;MPO;CYP1A1;IDO1 GO:0042744| hydrogen peroxide catabolic process GPX1;MPO;CAT GO:0006979| response to oxidative stress CAT;PTGS1;MPO;GPX1;SOD1;PTGS2 GO:0007568| aging CYP1A1;CNR1;HTR2A;SOD1;NAPEPLD;HMGCR;PTGS2;CAT;MPO GO:0007595| lactation SERPINC1;SLC29A1 GO:0019430| removal of superoxide radicals MPO;SOD1 GO:0007584| response to nutrient CNR1;SERPINC1;HMGCR;PPARG GO:0002438| acute inflammatory response to antigenic stimulus OPRM1;SERPINC1 21136:[DB14011 DB06258] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06258|Bimoclomol HSF1 common genes common pathways GO:0071276| cellular response to cadmium ion CYP1A2;SOD1;HSF1 GO:0070301| cellular response to hydrogen peroxide HSF1;CYP1B1 GO:0007584| response to nutrient PPARG;CNR1;HMGCR;HSF1 GO:0035865| cellular response to potassium ion CACNA1H;SOD1;HSF1 GO:0014823| response to activity HSF1;CAT GO:0008285| negative regulation of cell proliferation HSF1;PTGS2;OPRM1;CYP1B1;PPARG GO:0014070| response to organic cyclic compound CYP1A1;PPARG;TRPA1;ACAT1;HSF1;AANAT;CYP1A2;PTGS2 GO:0006351| transcription, DNA-dependent PPARG;HSF1 GO:0009408| response to heat TRPV1;TRPV3;SOD1;TRPV2;HSF1 GO:0010629| negative regulation of gene expression OPRD1;HSF1 GO:0032720| negative regulation of tumor necrosis factor production HSF1;CHRNA7;GPR18 GO:0051260| protein homooligomerization GLRA3;ACAT1;HSF1;GLRA1 GO:0071280| cellular response to copper ion CYP1A2;HSF1;CYP1A1 GO:0032355| response to estradiol stimulus CAT;HSF1;CYP1A2;PTGS2 GO:0034605| cellular response to heat HSF1;PTGS2;TRPV4;TRPV1 GO:0007283| spermatogenesis CNR1;SOD1;HSF1 GO:0010628| positive regulation of gene expression HSF1;TRPV4 GO:0043200| response to amino acid stimulus HSF1;GLRA3;GLRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;HSF1 GO:0008284| positive regulation of cell proliferation CHRNA7;HSF1;HTR1A;HTR2A;PTGS2;HMGCR GO:0070207| protein homotrimerization HSF1;TRPM8 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;HSF1 GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;PTGS2;CNR2;HSF1;CYP1A1;IDO1 GO:0071230| cellular response to amino acid stimulus HSF1;GLRA1 GO:0010243| response to organic nitrogen HSF1;PTGS2;TRPV1 GO:0006355| regulation of transcription, DNA-dependent HSF1;PPARG GO:0071407| cellular response to organic cyclic compound HSF1;CYP1B1;CYP1A1 21137:[DB14011 DB01260] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01260|Desonide NR3C1;CYP3A4 common genes CYP3A4 common pathways GO:0006915| apoptotic process VDAC1;NR3C1;GPX1 GO:0036378| CYP3A4 GO:0002933| CYP3A4;CYP3A7;CYP1A1;CYP3A5 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP3A7;HMGCR;CYP17A1;CYP3A5;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;CYP1A2;CYP3A7;PTGS2;HMGCR;CYP3A4;SOD1;CYP1B1;CYP17A1;CYP3A5;ALOX15;CYP2C19;IDO1;GSR;CYP2D6;CYP2C9;CYP1A1;CRYZ GO:0006355| regulation of transcription, DNA-dependent PPARG;NR3C1 GO:0006367| transcription initiation from RNA polymerase II promoter NR3C1;PPARG GO:0042737| drug catabolic process CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0000122| negative regulation of transcription from RNA polymerase II promoter NR3C1;TRPV1;TRPV4;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;NR3C1 GO:0007165| signal transduction CHRNA7;NR3C1;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;GPR55;HTR1A;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP3A5;CYP2D6 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0006351| transcription, DNA-dependent NR3C1;PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG;NR3C1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process PPARG;CYP2C9;PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD;PTGS1;NAAA;GPX1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 21138:[DB14011 DB05624] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05624|Teverelix GNRHR common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;CHRNA7;SMPD1;GPR18;PPARG;PLA2G1B;CACNA1I;GNRHR GO:0007186| G-protein coupled receptor signaling pathway CNR1;GPR12;HTR2A;GPR55;HTR1A;OPRD1;OPRM1;CNR2;GNRHR;GPR18;PPARG 21139:[DB14011 DB02929] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02929|K201 ANXA5 common genes common pathways GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;ANXA5;SOD1 GO:0002576| platelet degranulation SOD1;ANXA5 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;PTGS2;CYP1A2;SOD1;ANXA5 GO:0007165| signal transduction CHRNA7;CNR2;OPRM1;OPRD1;ANXA5;HTR1A;GPR55;GPR12;CNR1;HTR2A;CACNA1I;PLA2G1B;SMPD1;PPARG;GPR18 21140:[DB14011 DB04020] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways GO:0007165| signal transduction CHRNA7;GPR12;CNR1;HTR2A;GPR55;HTR1A;OPRD1;CNR2;OPRM1;ESR2;CACNA1I;PLA2G1B;GPR18;PPARG;SMPD1 GO:0006351| transcription, DNA-dependent PPARG;ESR2 GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2 GO:0030308| negative regulation of cell growth PPARG;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter ESR2;TRPV4;TRPV1;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG 21141:[DB14011 DB07256] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07256|3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE EPHB4 common genes common pathways GO:0007155| cell adhesion CYP1B1;EPHB4 GO:0001525| angiogenesis PTGS2;EPHB4;CYP1B1 21142:[DB14011 DB05119] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05119|Rilapladib PLA2G7 common genes common pathways GO:0016042| lipid catabolic process PLA2G7;NAPEPLD;PLA2G1B;DAGLA GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;PLA2G7;PTGS2;CYP1A2;HMGCR;NAPEPLD;CYP3A4;TRPV1;PLA2G1B;ALOX15;CYP2D6;DAGLA;CYP2C9;PPARG GO:0050729| positive regulation of inflammatory response TRPV4;PLA2G7 21143:[DB14011 DB11770] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11770|Talinolol CYP2D6 common genes CYP2D6 common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP1A1;CYP2D6;CYP2C19 GO:0051100| negative regulation of binding CYP2D6 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A7;CYP1A2;CYP3A4;CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9 GO:0006629| lipid metabolic process TRPV1;PLA2G1B;ALOX15;DAGLA;CYP2D6;CYP2C9;PPARG;PTGS1;NAAA;GPX1;CYP1A2;PTGS2;HMGCR;NAPEPLD;CYP3A4 GO:0033076| isoquinoline alkaloid metabolic process CYP2D6 GO:0070989| oxidative demethylation CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0042737| drug catabolic process CYP2D6;CYP3A5;CYP2C9;CYP1A2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2D6;CYP2C19;IDO1;GSR;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;GPX1;ALOX5;PTGS1 GO:0009804| coumarin metabolic process CYP2D6;CYP1A1 GO:0019369| arachidonic acid metabolic process FAAH;CYP1B1;ALOX15;CYP2D6;DAGLA GO:0090350| negative regulation of cellular organofluorine metabolic process CYP2D6 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;HMGCR;CYP3A4;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 21144:[DB14011 DB02840] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02840|4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2;HSP90AA1;TRPV1 GO:0043312| neutrophil degranulation ALOX5;CAT;HSP90AA1 GO:0046677| response to antibiotic SOD1;CYP1A1;HSP90AA1 GO:0007165| signal transduction CHRNA7;OPRD1;OPRM1;CNR2;HTR2A;GPR12;CNR1;HTR1A;GPR55;PLA2G1B;CACNA1I;SMPD1;GPR18;PPARG;HSP90AA1 GO:0009409| response to cold TRPM8;PPARG;HSP90AA1;TRPA1 GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 21145:[DB14011 DB07027] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07027|D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide F2 common genes common pathways GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade F2;CAT GO:0010468| regulation of gene expression CYP1A2;F2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;OPRM1;CNR2;CNR1;GPR12;HTR2A;HTR1A;GPR55;GPR18;PPARG;F2 GO:0009611| response to wounding CYP1A1;F2;GPX1 GO:0008284| positive regulation of cell proliferation F2;CHRNA7;HTR1A;HTR2A;PTGS2;HMGCR GO:0061844| F2;PLA2G1B GO:0001934| positive regulation of protein phosphorylation CHRNA7;F2 GO:0007166| cell surface receptor linked signaling pathway F2;TRPV1;TRPA1 21146:[DB14011 DB07723] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes PPARG common pathways GO:0071455| cellular response to hyperoxia PPARG GO:0071404| cellular response to low-density lipoprotein particle stimulus PPARG GO:0010742| macrophage derived foam cell differentiation PPARG GO:0046321| positive regulation of fatty acid oxidation PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG GO:0016525| negative regulation of angiogenesis PPARG GO:0033189| response to vitamin A PPARG;CYP1A1;CAT GO:0042493| response to drug ABCG2;ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;CAT;PTGS2;CYP1A2;SOD1;HTR2A GO:0006355| regulation of transcription, DNA-dependent PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG GO:0030224| monocyte differentiation PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B GO:0071300| cellular response to retinoic acid PPARG GO:0009612| response to mechanical stimulus TRPV4;PPARG GO:0045087| innate immune response PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV4;TRPV1 GO:0042594| response to starvation PPARG;ACAT1 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0030308| negative regulation of cell growth PPARG GO:0032526| response to retinoic acid PPARG GO:0045713| low-density lipoprotein particle receptor biosynthetic process PPARG GO:1905563| PPARG GO:0071306| cellular response to vitamin E PPARG GO:0002674| negative regulation of acute inflammatory response PPARG GO:0060100| positive regulation of phagocytosis, engulfment PPARG GO:0048714| positive regulation of oligodendrocyte differentiation PPARG GO:0048511| rhythmic process AANAT;PPARG GO:0010033| response to organic substance CYP1A2;PTGS2;SOD1;TRPA1;CYP1A1;PPARG GO:0045892| negative regulation of transcription, DNA-dependent PPARG GO:0031000| response to caffeine PPARG GO:0010871| negative regulation of receptor biosynthetic process PPARG GO:0030855| epithelial cell differentiation VDAC1;PPARG GO:0060965| negative regulation of gene silencing by miRNA PPARG GO:0031100| organ regeneration PPARG GO:0042593| glucose homeostasis CNR1;TRPV4;PPARG GO:0010891| negative regulation of sequestering of triglyceride PPARG GO:0043388| positive regulation of DNA binding PPARG GO:0033993| response to lipid PPARG GO:0032966| negative regulation of collagen biosynthetic process PPARG GO:0060850| regulation of transcription involved in cell fate commitment PPARG GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;CNR2;OPRM1;OPRD1;HTR1A;GPR55;HTR2A;GPR12;CNR1 GO:0015909| long-chain fatty acid transport PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG GO:0042752| regulation of circadian rhythm PPARG GO:0050872| white fat cell differentiation PPARG GO:1904706| PPARG GO:0071379| cellular response to prostaglandin stimulus PPARG GO:2000230| negative regulation of pancreatic stellate cell proliferation PPARG GO:1901558| PPARG GO:0061614| PPARG GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1 GO:0009409| response to cold TRPM8;PPARG;TRPA1 GO:0007507| heart development PPARG GO:0045165| cell fate commitment PPARG GO:0051974| negative regulation of telomerase activity PPARG GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;HMGCR;PTGS2;CYP1A2;NAAA;GPX1;PTGS1;CYP2C9;PPARG;CYP2D6;DAGLA;ALOX15;PLA2G1B;TRPV1 GO:0042953| lipoprotein transport PPARG GO:0006357| regulation of transcription from RNA polymerase II promoter PPARG GO:0048469| cell maturation PPARG GO:0043401| steroid hormone mediated signaling pathway PPARG GO:0045598| regulation of fat cell differentiation PPARG GO:0006351| transcription, DNA-dependent PPARG GO:0045600| positive regulation of fat cell differentiation HTR2A;PPARG GO:0010887| negative regulation of cholesterol storage PPARG GO:0071380| cellular response to prostaglandin E stimulus PPARG GO:0019395| fatty acid oxidation PPARG GO:0001890| placenta development SOD1;PPARG GO:0055088| lipid homeostasis PPARG GO:0043627| response to estrogen stimulus PPARG GO:0007584| response to nutrient CNR1;HMGCR;PPARG GO:0043537| negative regulation of blood vessel endothelial cell migration PPARG GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CYP1B1;PPARG GO:0060336| negative regulation of interferon-gamma-mediated signaling pathway PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0006919| activation of caspase activity PPARG GO:0010745| negative regulation of macrophage derived foam cell differentiation PPARG GO:0014070| response to organic cyclic compound AANAT;ACAT1;CYP1A2;PTGS2;TRPA1;CYP1A1;PPARG GO:0048662| negative regulation of smooth muscle cell proliferation PPARG GO:0007165| signal transduction CHRNA7;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:1905461| PPARG GO:0019216| regulation of lipid metabolic process CNR1;HMGCR;PPARG;CYP1A1 GO:0035357| peroxisome proliferator activated receptor signaling pathway PPARG GO:0032869| cellular response to insulin stimulus PPARG;PLA2G1B GO:0060694| regulation of cholesterol transporter activity PPARG 21147:[DB14011 DB08038] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 21148:[DB14011 DB04711] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04711|Iodipamide ALB common genes common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;HMGCR;PTGS2;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0098869| PTGS2;GPX1;PTGS1;CAT;ALB;GSR 21149:[DB14011 DB03510] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways GO:0042594| response to starvation ACAT1;PPARG;ADSSL1 GO:0002376| immune system process IDO1;ADSSL1 21150:[DB14011 DB04830] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04830|Buformin SLC22A1 common genes common pathways GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV4;CACNA1I;VDAC1;TRPV1;TRPA1;ABCC1;SLC22A1;CACNA1G GO:0051260| protein homooligomerization SLC22A1;GLRA1;GLRA3;ACAT1 GO:0006812| cation transport SLC22A1;TRPM8 GO:0006811| ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;GLRA3;TRPV1;VDAC1;CACNA1I;TRPV4;GLRB;TRPM8;CACNA1G;SLC22A1;GLRA1;TRPA1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A1 21151:[DB14011 DB06681] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06681|Belatacept CD86;CD80 common genes common pathways GO:0002376| immune system process CD86;IDO1 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;GPX1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;PPARG GO:0008284| positive regulation of cell proliferation CD86;CHRNA7;HTR2A;HTR1A;HMGCR;PTGS2 GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CD86;PLA2G1B;CACNA1I;PPARG;GPR18;SMPD1 GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0016032| viral reproduction CD86;VDAC1;HTR2A;CD80 GO:0006955| immune response CD86;CNR2;OPRD1 GO:0035556| intracellular signal transduction CD80;PLA2G1B 21152:[DB14011 DB04664] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP2B6 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CRYZ;CYP2B6;ALOX15;CYP3A5;CYP17A1;CYP2D6;GSR;IDO1;CYP2C19;CYP1B1;CYP3A4;SOD1;PTGS2;CYP3A7;CYP1A2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP2B6;CYP1B1;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP3A7;CYP1A2;HMGCR;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP2B6 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;CYP2B6;PTGS1;CYP1A2;CYP3A7;CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2B6;CYP2C9 21153:[DB14011 DB04534] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04534|5-Nitroindazole NOS2;NOS3 common genes common pathways GO:0019430| removal of superoxide radicals SOD1;NOS3 GO:0009408| response to heat TRPV2;TRPV3;SOD1;TRPV1;NOS3 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0001525| angiogenesis PTGS2;NOS3;CYP1B1 GO:0045776| negative regulation of blood pressure NOS2;NOS3;CNR1 GO:1902042| GPX1;NOS3 GO:0008217| regulation of blood pressure SOD1;PTGS2;PTGS1;PPARG;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CYP1B1;PPARG;PTGS2;OPRM1 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3;NOS2 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;NOS2;GSR;NOS3 GO:0006801| superoxide metabolic process SOD1;NOS2 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP1A2;HMGCR;CYP3A4;SOD1;PTGS1;ALOX5;GPX1;CAT;CYP1A1;CYP2C9;NOS2;CRYZ;CYP1B1;CYP17A1;ALOX15;CYP3A5;CYP2D6;NOS3;CYP2C19;GSR;IDO1 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0042311| vasodilation GPX1;NOS3 GO:0030324| lung development NOS3;CYP1A2 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0032496| response to lipopolysaccharide NOS2;CYP1A1;IDO1;PTGS2;CNR2;OPRM1;CYP1A2;CNR1 GO:0007623| circadian rhythm AANAT;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 21154:[DB14011 DB08480] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08480|4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN MAOB common genes common pathways GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0009636| response to toxin CYP1B1;MAOB;CYP1A1;GPX1;CAT GO:0010269| response to selenium ion MAOB;GPX1 GO:0045471| response to ethanol CAT;HMGCR;OPRM1;SOD1;CNR1;MAOB GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1;MAOB GO:0032496| response to lipopolysaccharide MAOB;CYP1A1;IDO1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0055114| oxidation-reduction process CAT;GPX1;ALOX5;PTGS1;CYP3A4;SOD1;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1B1;CYP1A1;CYP2C9;CRYZ;MAOB GO:0042493| response to drug CAT;SOD1;HTR2A;CYP1A2;PTGS2;ABCG2;TRPA1;CYP1A1;PPARG;SMPD1;ABCC1;MAOB GO:0022900| electron transport chain CYP1A2;MAOB;GSR;IDO1 21155:[DB14011 DB06897] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways GO:0008283| cell proliferation PLK1;GPX1;HTR1A;CYP1A1 GO:0043066| negative regulation of apoptotic process GPX1;PLK1;CAT;PTGS2;HMGCR;SOD1 GO:0000122| negative regulation of transcription from RNA polymerase II promoter PLK1;TRPV4;TRPV1;PPARG 21156:[DB14011 DB05150] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05150|CAD106 APP common genes common pathways GO:0000187| activation of MAPK activity PLA2G1B;APP;CHRNA7;SOD1 GO:0006915| apoptotic process GPX1;APP;VDAC1 GO:0070374| positive regulation of ERK1 and ERK2 cascade APP;ALOX15;TRPV4;HTR2A;GPR55;HMGCR;OPRM1;CHRNA7 GO:0051262| protein tetramerization CAT;HMGCR;APP GO:2000463| positive regulation of excitatory postsynaptic membrane potential CHRNA7;APP GO:0010628| positive regulation of gene expression TRPV4;APP GO:0010468| regulation of gene expression APP;CYP1A2 GO:0098815| CHRNA7;APP GO:0007186| G-protein coupled receptor signaling pathway APP;PPARG;GPR18;OPRM1;CNR2;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A GO:0045429| positive regulation of nitric oxide biosynthetic process APP;TRPV1;PTGS2;OPRM1 GO:0006979| response to oxidative stress PTGS2;SOD1;PTGS1;GPX1;CAT;APP GO:0051260| protein homooligomerization GLRA1;APP;ACAT1;GLRA3 GO:0050808| synapse organization CHRNA7;APP GO:0019731| antibacterial humoral response APP;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;APP GO:0051247| positive regulation of protein metabolic process APP;CHRNA7 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;APP GO:0046330| positive regulation of JNK cascade TRPV4;APP GO:1905906| CHRNA7;APP GO:0007611| learning or memory APP;CNR1;CHRNA7 GO:0007612| learning VDAC1;APP;PTGS2 GO:0008203| cholesterol metabolic process APP;CAT;HMGCR GO:0010288| response to lead ion APP;CAT GO:0007155| cell adhesion CYP1B1;APP GO:0045087| innate immune response APP;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter APP;PPARG;TRPV1;TRPV4 GO:0002576| platelet degranulation APP;SOD1 GO:0007626| locomotory behavior APP;OPRM1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;PPARG;PLA2G1B GO:0008344| adult locomotory behavior APP;OPRD1 GO:0008285| negative regulation of cell proliferation APP;PPARG;CYP1B1;PTGS2;OPRM1 GO:0061844| PLA2G1B;APP GO:0032930| positive regulation of superoxide anion generation APP;SOD1 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway APP;OPRD1;OPRM1 GO:0007613| memory CHRNA7;PTGS2;HTR2A;CNR1;APP GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;APP GO:0040014| regulation of multicellular organism growth APP;SOD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2;OPRD1 GO:1900273| CHRNA7;APP GO:1902004| APP;CHRNA7 GO:0001934| positive regulation of protein phosphorylation CHRNA7;APP GO:0007268| synaptic transmission HTR2A;GLRA3;OPRM1;OPRD1;VDAC1;GLRB;GLRA1;CACNA1G;APP GO:0010629| negative regulation of gene expression OPRD1;APP GO:0071320| cellular response to cAMP APP;AANAT GO:0008542| visual learning HMGCR;APP GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;PLA2G1B;APP GO:0001774| microglial cell activation TRPV1;APP GO:1990090| APP;TRPV1 GO:0007399| nervous system development APP;SMPD1;GLRB GO:2000310| regulation of N-methyl-D-aspartate selective glutamate receptor activity APP;OPRM1 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1;SOD1;APP;SMPD1;PPARG;TRPV1;CYP1B1;IDO1 21157:[DB14011 DB01208] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes CYP1A2 common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;AANAT;ACAT1;TRPA1;CYP1A1;PPARG GO:0045333| cellular respiration CYP1A2 GO:0006811| ion transport GLRA3;SLC22A5;CACNA1H;TRPV3;CHRNA7;TRPV2;GLRA1;TRPA1;CACNA1G;TRPM8;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1 GO:0009820| alkaloid metabolic process CYP2D6;CYP1A2 GO:0006725| cellular aromatic compound metabolic process CYP1A2;CYP1B1 GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCB1;ABCC2;ABCG2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion CYP1A2;SOD1 GO:0043627| response to estrogen stimulus PPARG;ABCC2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0032870| cellular response to hormone stimulus CACNA1H;ABCC2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2C9;CYP2D6;CYP3A5 GO:0097267| CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0042738| exogenous drug catabolic process CYP2C19;CYP2C9;CYP3A4;CYP1A2 GO:0007565| female pregnancy ABCC2;IDO1 GO:0009408| response to heat TRPV1;ABCC2;TRPV2;TRPV3;SOD1 GO:0042752| regulation of circadian rhythm TOP2A;PPARG GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP1A2;CYP3A4 GO:0006778| porphyrin-containing compound metabolic process CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;PTGS1;CYP2C9;CYP1B1;CYP3A5;CYP2D6;CYP2C19 GO:0043065| positive regulation of apoptotic process SMPD1;PPARG;TOP2A;CYP1B1;TRPV1;IDO1;PTGS2;SOD1;CNR1 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006629| lipid metabolic process NAAA;GPX1;PTGS1;NAPEPLD;CYP3A4;HMGCR;CYP1A2;PTGS2;DAGLA;CYP2D6;ALOX15;TRPV1;PLA2G1B;CYP2C9;PPARG GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;SOD1;CYP1A2 GO:0009404| toxin metabolic process CYP1A2;CYP1A1;CYP1B1 GO:0055085| transmembrane transport SLC22A5;TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCC2;ABCG2;CACNA1I;ABCB1;TRPV4;VDAC1;TRPV1 GO:0010033| response to organic substance PTGS2;CYP1A2;SOD1;PPARG;CYP1A1;TRPA1 GO:0071356| cellular response to tumor necrosis factor TRPV1;ABCC2 GO:0048511| rhythmic process AANAT;TOP2A;PPARG GO:0008202| steroid metabolic process CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP1A1;CYP3A4;CYP1A2;CYP3A7;HMGCR GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0006810| transport ABCC1;CACNA1I;ABCB1;TRPV1;ABCG2;ABCC2;TRPV2 GO:0010468| regulation of gene expression CYP1A2 GO:0006979| response to oxidative stress GPX1;PTGS1;CAT;PTGS2;SOD1;ABCC2 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP3A4 GO:0071280| cellular response to copper ion CYP1A1;CYP1A2 GO:0099133| ABCC2;ABCC1 GO:0022900| electron transport chain CYP1A2;IDO1;GSR GO:0046685| response to arsenic-containing substance CYP1A1;ABCC2 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCB1;ABCC2;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CAT GO:0055114| oxidation-reduction process CYP2C19;IDO1;GSR;CYP2D6;CYP17A1;CYP3A5;ALOX15;CYP1B1;CRYZ;CYP1A1;CYP2C9;CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;CYP1A2;CYP3A7;PTGS2 GO:0032496| response to lipopolysaccharide ABCC2;IDO1;CYP1A1;CYP1A2;OPRM1;CNR2;PTGS2;CNR1 GO:0042737| drug catabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A4;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0032259| methylation CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;TOP2A;PPARG GO:0035902| response to immobilization stress CYP1A2;PPARG;CYP1A1 21158:[DB14011 DB01686] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01686|N,N-dimethylarginine NOS2;NOS3 common genes common pathways GO:0045766| positive regulation of angiogenesis NOS3;CYP1B1;CHRNA7 GO:0001666| response to hypoxia CHRNA7;CAT;NOS2;CYP1A1 GO:0030324| lung development NOS3;CYP1A2 GO:0043542| endothelial cell migration NOS3;CYP1B1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR2;PTGS2;CNR1;IDO1;CYP1A1;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2;PTGS1 GO:0007623| circadian rhythm NOS2;AANAT GO:0042311| vasodilation NOS3;GPX1 GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;ALOX5;GPX1;PTGS1;CAT;NOS2;CRYZ;CYP2C9;CYP1A1;CYP1B1;CYP2D6;NOS3;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0006801| superoxide metabolic process NOS2;SOD1 GO:0050796| regulation of insulin secretion CNR1;NOS2 GO:0045454| cell redox homeostasis GPX1;GSR;NOS3;NOS2 GO:0006809| nitric oxide biosynthetic process CYP1B1;NOS3;NOS2 GO:0002227| innate immune response in mucosa PLA2G1B;NOS2 GO:0043267| negative regulation of potassium ion transport NOS3;HTR2A GO:1902042| NOS3;GPX1 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;NOS3;PPARG GO:0008285| negative regulation of cell proliferation CYP1B1;NOS3;PPARG;OPRM1;PTGS2 GO:0045776| negative regulation of blood pressure CNR1;NOS2;NOS3 GO:0001525| angiogenesis PTGS2;NOS3;CYP1B1 GO:0010629| negative regulation of gene expression NOS2;OPRD1 GO:0019430| removal of superoxide radicals NOS3;SOD1 GO:0009408| response to heat TRPV2;SOD1;TRPV3;NOS3;TRPV1 21159:[DB14011 DB06899] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06899|N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOTHIAZIN-4-YL]ETHYL}ACETAMIDE REN common genes common pathways GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;REN;SOD1;PTGS2;CYP1A2 GO:0051591| response to cAMP AANAT;REN GO:0035902| response to immobilization stress CYP1A2;REN;PPARG;CYP1A1 GO:0001822| kidney development REN;CAT GO:0032496| response to lipopolysaccharide REN;CYP1A1;IDO1;CNR1;OPRM1;CYP1A2;PTGS2;CNR2 GO:0042493| response to drug HTR2A;SOD1;PTGS2;CYP1A2;CAT;CYP1A1;PPARG;TRPA1;REN;ABCC1;SMPD1;ABCG2 GO:0008217| regulation of blood pressure PTGS1;PTGS2;SOD1;REN;PPARG GO:0048469| cell maturation REN;PPARG 21160:[DB14011 DB08620] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08620|{(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide CHRFAM7A common genes common pathways GO:0006811| ion transport TRPV2;CHRNA7;TRPV3;CACNA1H;GLRA3;CHRFAM7A;VDAC1;GLRB;TRPV4;CACNA1I;TRPV1;TRPM8;CACNA1G;TRPA1;GLRA1 GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CHRFAM7A;HTR2A;GPR12;CNR1 GO:0034220| ion transmembrane transport CHRNA7;CHRFAM7A;GLRA3;GLRB;TRPV1;TRPA1;GLRA1 21161:[DB14011 DB13083] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB13083|Talarozole CYP26A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP2C9;PTGS1;CYP3A4;CYP3A7;CYP1A2;CYP26A1 GO:0016125| sterol metabolic process CYP17A1;CYP1B1;CYP26A1 GO:0055114| oxidation-reduction process PTGS1;ALOX5;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP26A1;SOD1;CYP3A4;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CRYZ;CYP2C9;CYP1A1 21162:[DB14011 DB04287] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04287|(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid PLA2G2A common genes common pathways GO:0050482| arachidonic acid secretion PLA2G2A;PLA2G1B GO:0050729| positive regulation of inflammatory response PLA2G2A;TRPV4 GO:0036150| PLA2G2A;PLA2G1B GO:0006629| lipid metabolic process TRPV1;PLA2G1B;CYP2D6;DAGLA;ALOX15;PLA2G2A;PPARG;CYP2C9;NAAA;PTGS1;GPX1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD GO:0036148| PLA2G1B;PLA2G2A GO:0036149| PLA2G2A;PLA2G1B GO:0036152| PLA2G2A;PLA2G1B GO:0006644| phospholipid metabolic process NAPEPLD;PLA2G1B;PLA2G2A GO:0070374| positive regulation of ERK1 and ERK2 cascade TRPV4;PLA2G2A;ALOX15;CHRNA7;OPRM1;HMGCR;GPR55;HTR2A GO:0016042| lipid catabolic process NAPEPLD;PLA2G1B;DAGLA;PLA2G2A GO:0006654| phosphatidic acid biosynthetic process PLA2G2A;PLA2G1B GO:0036151| PLA2G2A;PLA2G1B GO:0050830| defense response to Gram-positive bacterium PLA2G1B;PLA2G2A 21163:[DB14011 DB08354] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08354|2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0006355| regulation of transcription, DNA-dependent CSNK2A1;PPARG GO:0016236| macroautophagy VDAC1;CSNK2A1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;HMGCR;CSNK2A1;PTGS2;CHRNA7 GO:0048511| rhythmic process PPARG;AANAT;CSNK2A1 GO:0006915| apoptotic process VDAC1;CSNK2A1;GPX1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2;CSNK2A1 GO:0006351| transcription, DNA-dependent PPARG;CSNK2A1 GO:0007165| signal transduction CNR2;OPRM1;CSNK2A1;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;CHRNA7;SMPD1;PPARG;GPR18;CACNA1I;PLA2G1B 21164:[DB14011 DB01745] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01745|N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process PRSS1;ABCC1 21165:[DB14011 DB00403] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00403|Ceruletide CCKAR common genes common pathways GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger HTR2A;OPRM1;OPRD1;CCKAR GO:0007186| G-protein coupled receptor signaling pathway CCKAR;GPR18;PPARG;OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;HTR1A;GPR55 GO:0007584| response to nutrient PPARG;CCKAR;CNR1;HMGCR GO:0046883| regulation of hormone secretion CCKAR;HTR2A;HTR1A GO:0007165| signal transduction CCKAR;SMPD1;PPARG;GPR18;PLA2G1B;CACNA1I;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A;CHRNA7 GO:0032870| cellular response to hormone stimulus CACNA1H;CCKAR GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;CCKAR;TRPV1;TRPV4 21166:[DB14011 DB07985] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07985|+/-METHYL 4-(AMINOIMINOMETHYL)-BETA-[3- INH (AMINOIMINO)PHENYL]BENZENE PENTANOATE PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 21167:[DB14011 DB04150] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04150|Threonine Derivative PAM common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;PAM GO:0007595| lactation PAM;SLC29A1 GO:0009268| response to pH TRPV1;PAM GO:0006357| regulation of transcription from RNA polymerase II promoter PAM;PPARG GO:0008152| metabolic process SMPD1;PAM;ACAT1 GO:0007507| heart development PPARG;PAM GO:0009404| toxin metabolic process CYP1A2;CYP1A1;PAM;CYP1B1 GO:0046688| response to copper ion PAM;SOD1;AANAT GO:0001666| response to hypoxia CAT;CHRNA7;CYP1A1;PAM GO:0032355| response to estradiol stimulus PAM;CYP1A2;PTGS2;CAT GO:0051260| protein homooligomerization PAM;GLRA1;ACAT1;GLRA3 GO:0042493| response to drug ABCG2;CYP1A1;PPARG;TRPA1;PAM;ABCC1;SMPD1;CAT;HTR2A;SOD1;PTGS2;CYP1A2 GO:0055114| oxidation-reduction process ALOX5;GPX1;PTGS1;CAT;HMGCR;CYP1A2;PTGS2;CYP3A7;SOD1;CYP3A4;CYP1B1;IDO1;GSR;CYP2C19;CYP2D6;CYP3A5;ALOX15;CYP17A1;PAM;CRYZ;CYP1A1;CYP2C9 GO:0060135| maternal process involved in female pregnancy CNR1;PAM 21168:[DB14011 DB04716] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways GO:0065009| regulation of molecular function JAK1;TRPV1;JAK3 GO:0007165| signal transduction PLA2G1B;CACNA1I;PPARG;GPR18;JAK2;SMPD1;CHRNA7;GPR55;HTR1A;CNR1;GPR12;HTR2A;OPRM1;CNR2;OPRD1 GO:0010811| positive regulation of cell-substrate adhesion ALOX15;JAK2 GO:0007204| elevation of cytosolic calcium ion concentration HTR2A;OPRM1;JAK2;TRPV1;TRPV4 GO:0050729| positive regulation of inflammatory response TRPV4;JAK2 GO:0008285| negative regulation of cell proliferation OPRM1;PTGS2;JAK2;PPARG;CYP1B1 GO:0006919| activation of caspase activity JAK2;PPARG GO:0035556| intracellular signal transduction DAPK3;TYK2;JAK3;PLA2G1B;JAK1;JAK2 GO:0043065| positive regulation of apoptotic process TRPV1;CYP1B1;IDO1;SMPD1;JAK2;PPARG;DAPK3;PTGS2;CNR1;SOD1 GO:0050727| regulation of inflammatory response JAK2;PTGS2 GO:0006351| transcription, DNA-dependent DAPK3;PPARG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation JAK2;HTR2A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;JAK2 GO:0006954| inflammatory response TRPV1;ALOX15;IDO1;PTGS2;CNR2;JAK3;PTGS1;ALOX5 GO:0008631| induction of apoptosis by oxidative stress GPX1;CYP1B1;JAK2 GO:0032693| negative regulation of interleukin-10 production IDO1;JAK3 GO:0043524| negative regulation of neuron apoptosis JAK2;SOD1 GO:0045429| positive regulation of nitric oxide biosynthetic process JAK2;TRPV1;OPRM1;PTGS2 GO:0043388| positive regulation of DNA binding PPARG;JAK2 GO:0006979| response to oxidative stress JAK2;CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0002376| immune system process IDO1;JAK2;JAK3 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade JAK2;CAT GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;JAK2;GPR55;HTR1A;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0006915| apoptotic process DAPK3;GPX1;JAK2;VDAC1 GO:0034612| response to tumor necrosis factor JAK2;PTGS2 GO:0045087| innate immune response JAK3;TYK2;PPARG;JAK2;JAK1 GO:0035722| interleukin-12-mediated signaling pathway TYK2;SOD1;JAK1;JAK2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;JAK2 GO:0046677| response to antibiotic JAK1;JAK2;CYP1A1;SOD1 GO:0032496| response to lipopolysaccharide CNR1;OPRM1;CYP1A2;PTGS2;CNR2;IDO1;CYP1A1;JAK2 GO:0042127| regulation of cell proliferation JAK2;JAK1;PTGS2;PTGS1;TYK2 GO:0033194| response to hydroperoxide JAK2;GPX1 GO:0006355| regulation of transcription, DNA-dependent PPARG;DAPK3 21169:[DB14011 DB06835] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 21170:[DB14011 DB01003] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways GO:0006970| response to osmotic stress TRPV4;KCNMA1 GO:0051592| response to calcium ion AANAT;KCNMA1 GO:0043065| positive regulation of apoptotic process CYP1B1;TRPV1;IDO1;SMPD1;PPARG;PTGS2;SOD1;CNR1;KCNMA1 GO:0060083| smooth muscle contraction involved in micturition TRPV1;KCNMA1 GO:0034765| regulation of ion transmembrane transport KCNMA1;CACNA1H;CACNA1I;CACNA1G GO:0006811| ion transport TRPA1;GLRA1;CACNA1G;TRPM8;TRPV1;TRPV4;GLRB;CACNA1I;VDAC1;KCNMA1;GLRA3;CACNA1H;TRPV3;CHRNA7;TRPV2 GO:0043542| endothelial cell migration CYP1B1;S100P GO:0043312| neutrophil degranulation CAT;ALOX5;S100P GO:0034465| response to carbon monoxide KCNMA1;SOD1 GO:0042391| regulation of membrane potential GLRB;CACNA1G;GLRA1;CACNA1H;KCNMA1 GO:0055085| transmembrane transport TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;VDAC1;TRPV4;CACNA1I;TRPV1;KCNMA1;TRPV3;CACNA1H;TRPV2 GO:0001666| response to hypoxia KCNMA1;CAT;CHRNA7;CYP1A1 GO:0010033| response to organic substance TRPA1;PPARG;CYP1A1;S100P;CYP1A2;PTGS2;SOD1 21171:[DB14011 DB05311] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05311|Ecallantide KLKB1 common genes common pathways GO:0006954| inflammatory response ALOX15;IDO1;TRPV1;KLKB1;CNR2;PTGS2;ALOX5;PTGS1 21172:[DB14011 DB11597] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 21173:[DB14011 DB07033] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways GO:0043524| negative regulation of neuron apoptosis SOD1;PDPK1 GO:0035556| intracellular signal transduction PLA2G1B;PDPK1 GO:0006351| transcription, DNA-dependent PDPK1;PPARG GO:0032869| cellular response to insulin stimulus PLA2G1B;PDPK1;PPARG GO:0006355| regulation of transcription, DNA-dependent PPARG;PDPK1 GO:0045766| positive regulation of angiogenesis CHRNA7;PDPK1;CYP1B1 21174:[DB14011 DB06902] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06902|4-(1-methyl-1-phenylethyl)phenol ESRRG common genes common pathways GO:0006351| transcription, DNA-dependent ESRRG;PPARG GO:0043401| steroid hormone mediated signaling pathway ESRRG;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;ESRRG;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter PPARG;ESRRG GO:0006355| regulation of transcription, DNA-dependent ESRRG;PPARG GO:0045893| positive regulation of transcription, DNA-dependent ESRRG;PPARG 21175:[DB14011 DB00551] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB00551|Acetohydroxamic acid ureC;MMP12 common genes common pathways GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;TRPV1;TRPV4;MMP12 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MMP12 GO:0042060| wound healing ALOX15;OPRM1;MMP12 GO:0010628| positive regulation of gene expression MMP12;TRPV4 21176:[DB14011 DB11740] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11740|MK-1775 WEE1 common genes common pathways 21177:[DB14011 DB03408] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03408|gamma-Glutamylcysteine GSS common genes common pathways GO:0031667| response to nutrient levels GSS;SOD1 GO:0007399| nervous system development SMPD1;GLRB;GSS GO:0009410| response to xenobiotic stimulus GSS;GPX1 GO:0034612| response to tumor necrosis factor GSS;PTGS2 GO:0046686| response to cadmium ion GSS;CAT GO:0043200| response to amino acid stimulus GSS;GLRB;GLRA3 GO:0007568| aging CYP1A1;GSS;HMGCR;PTGS2;SOD1;HTR2A;CNR1;NAPEPLD;CAT GO:0006979| response to oxidative stress GSS;CAT;PTGS1;GPX1;SOD1;PTGS2 21178:[DB14011 DB04209] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04209|Dequalinium XIAP;CNGA1;KCNMA1 common genes common pathways GO:0055085| transmembrane transport CNGA1;TRPV2;KCNMA1;CACNA1H;TRPV3;ABCG2;TRPM8;CACNA1I;TRPV4;VDAC1;TRPV1;TRPA1;CACNA1G;ABCC1 GO:0006915| apoptotic process GPX1;XIAP;VDAC1 GO:0001666| response to hypoxia CYP1A1;KCNMA1;CAT;CHRNA7 GO:0006810| transport CNGA1;TRPV2;CACNA1I;TRPV1;ABCG2;ABCC1 GO:0042391| regulation of membrane potential CNGA1;KCNMA1;CACNA1H;GLRB;GLRA1;CACNA1G GO:0034465| response to carbon monoxide SOD1;KCNMA1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;XIAP GO:0043066| negative regulation of apoptotic process CAT;GPX1;SOD1;XIAP;PTGS2;HMGCR GO:0006811| ion transport TRPM8;CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPA1;GLRA1;CACNA1G;CHRNA7;CNGA1;TRPV2;GLRA3;KCNMA1;TRPV3;CACNA1H GO:0050896| response to stimulus TRPM8;TRPA1;CNGA1 GO:0007601| visual perception GLRB;CYP1B1;GLRA1;CRYZ;CNGA1 GO:0060083| smooth muscle contraction involved in micturition TRPV1;KCNMA1 GO:0007165| signal transduction CNGA1;CHRNA7;OPRM1;CNR2;OPRD1;GPR55;HTR1A;HTR2A;CNR1;GPR12;PLA2G1B;CACNA1I;SMPD1;PPARG;GPR18 GO:0034765| regulation of ion transmembrane transport CACNA1I;CACNA1G;CACNA1H;KCNMA1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;XIAP;PTGS2 GO:0051592| response to calcium ion AANAT;KCNMA1 GO:0006970| response to osmotic stress KCNMA1;TRPV4 GO:0043065| positive regulation of apoptotic process KCNMA1;CNR1;SOD1;PTGS2;IDO1;TRPV1;CYP1B1;PPARG;SMPD1 GO:0050727| regulation of inflammatory response XIAP;PTGS2 21179:[DB14011 DB01830] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1;LCK GO:0045087| innate immune response LCK;PPARG GO:0042493| response to drug CYP1A2;PTGS2;SOD1;HTR2A;CAT;SMPD1;ABCC1;PPARG;CYP1A1;TRPA1;LCK;ABCG2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;LCK GO:0051209| release of sequestered calcium ion into cytosol LCK;TRPV1;TRPA1;HTR2A GO:0016032| viral reproduction VDAC1;LCK;HTR2A GO:0030217| T cell differentiation LCK;GPR18 GO:0006919| activation of caspase activity PPARG;LCK 21180:[DB14011 DB08933] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes CYP3A4;CYP2C19 common pathways GO:0036378| CYP3A4 GO:0002933| CYP1A1;CYP3A5;CYP3A4;CYP3A7 GO:0009822| alkaloid catabolic process CYP2D6;CYP3A5;CYP3A4 GO:0042359| vitamin D metabolic process CYP1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C19 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;ALOX15;CYP3A5;CYP2D6;CYP2C19;GSR;IDO1;CYP1B1;CYP3A4;SOD1;CYP3A7;PTGS2;CYP1A2;HMGCR;CAT;PTGS1;ALOX5;GPX1 GO:0042737| drug catabolic process CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP1B1;CYP2C19;CYP1A1;CYP2C9 GO:0097267| CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP3A5;CYP2D6;CYP2C9 GO:0008209| androgen metabolic process CYP3A4 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2D6;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0006629| lipid metabolic process GPX1;NAAA;PTGS1;HMGCR;PTGS2;CYP1A2;CYP3A4;NAPEPLD;PLA2G1B;TRPV1;CYP2D6;DAGLA;ALOX15;PPARG;CYP2C9 GO:0006706| steroid catabolic process CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C19;CYP3A5;CYP2C9;PTGS1;CYP3A7;CYP1A2;CYP3A4 21181:[DB14011 DB04424] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04424|RPR128515 PRSS1 common genes common pathways GO:0009235| cobalamin metabolic process ABCC1;PRSS1 21182:[DB14011 DB05465] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0031100| organ regeneration PPARG;FLT3 GO:0014068| positive regulation of phosphatidylinositol 3-kinase cascade CAT;FLT3;PDGFD GO:0043406| positive regulation of MAP kinase activity HTR2A;FLT3;PDGFD GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;PDGFD;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0008284| positive regulation of cell proliferation CHRNA7;HTR2A;FLT3;HTR1A;PDGFD;HMGCR;PTGS2 GO:0071230| cellular response to amino acid stimulus GLRA1;PDGFD GO:0010243| response to organic nitrogen PTGS2;FLT3;TRPV1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;PDGFD GO:0071345| cellular response to cytokine stimulus TRPV1;FLT3 GO:0051781| positive regulation of cell division CAT;PDGFD GO:0048146| positive regulation of fibroblast proliferation PLA2G1B;PDGFD GO:0070301| cellular response to hydrogen peroxide CYP1B1;PDGFD 21183:[DB14011 DB11632] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes CYP2C19 common pathways GO:0008210| estrogen metabolic process CYP1B1;COMT GO:0048265| response to pain TRPV1;TRPA1;COMT GO:0042493| response to drug SOD1;HTR2A;PTGS2;CYP1A2;CAT;TRPA1;CYP1A1;PPARG;ABCC1;SMPD1;COMT;ABCG2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP17A1;CYP3A5;ALOX15;CYP2C19;CYP2C8;IDO1;GSR;CYP2D6;CYP1B1;CYP3A4;SOD1;CYP1A2;CYP3A7;PTGS2;HMGCR;CAT;ALOX5;GPX1;PTGS1 GO:0032259| methylation COMT;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP1B1;CYP1A1;CYP2C9;CYP1A2 GO:0007612| learning PTGS2;VDAC1;COMT GO:0032496| response to lipopolysaccharide COMT;CYP1A1;IDO1;CNR2;PTGS2;OPRM1;CYP1A2;CNR1 GO:0007614| short-term memory CHRNA7;COMT GO:0002933| CYP1A1;CYP2C8;CYP3A5;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP17A1;CYP3A5;CYP2D6;CYP2C8;CYP2C19 GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP2C8;CYP1A2;CYP3A4 GO:0007565| female pregnancy IDO1;COMT GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0043627| response to estrogen stimulus COMT;PPARG GO:0051930| regulation of sensory perception of pain OPRM1;OPRD1;COMT GO:0014070| response to organic cyclic compound ACAT1;AANAT;CYP1A2;PTGS2;COMT;TRPA1;CYP1A1;PPARG GO:0070989| oxidative demethylation CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2D6;CYP2C8 GO:0048662| negative regulation of smooth muscle cell proliferation COMT;PPARG GO:0097267| CYP2C8;CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP1A2 GO:0032502| developmental process CYP1A1;COMT 21184:[DB14011 DB02398] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02398|6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLAU;CACNA1I;PLA2G1B;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7 GO:0001666| response to hypoxia CYP1A1;PLAU;CAT;CHRNA7 GO:0042127| regulation of cell proliferation PTGS1;PTGS2;PLAU GO:0043312| neutrophil degranulation PLAU;ALOX5;CAT 21185:[DB14011 DB02676] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways GO:0006939| smooth muscle contraction PDE4D;HTR2A GO:0007165| signal transduction CHRNA7;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;PDE4D;OPRD1;CACNA1I;PLA2G1B;PPARG;GPR18;SMPD1 GO:0071320| cellular response to cAMP AANAT;PDE4D GO:0002027| regulation of heart rate PDE4D;CACNA1G GO:0007186| G-protein coupled receptor signaling pathway CNR2;OPRM1;PDE4D;OPRD1;HTR1A;GPR55;GPR12;CNR1;HTR2A;PPARG;GPR18 GO:0007568| aging CYP1A1;CAT;CNR1;SOD1;HTR2A;NAPEPLD;HMGCR;PDE4D;PTGS2 GO:0030593| neutrophil chemotaxis PDE4D;PLA2G1B 21186:[DB14011 DB05064] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05064|INCB13739 HSD11B1 common genes common pathways GO:0006629| lipid metabolic process PLA2G1B;TRPV1;ALOX15;DAGLA;CYP2D6;PPARG;CYP2C9;NAAA;GPX1;PTGS1;HSD11B1;CYP1A2;PTGS2;HMGCR;CYP3A4;NAPEPLD GO:0055114| oxidation-reduction process CYP1B1;CYP2D6;CYP2C19;GSR;IDO1;CYP17A1;ALOX15;CYP3A5;CRYZ;CYP2C9;CYP1A1;PTGS1;ALOX5;GPX1;HSD11B1;CAT;HMGCR;CYP3A7;PTGS2;CYP1A2;SOD1;CYP3A4 GO:0030324| lung development HSD11B1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP1A2;HMGCR;HSD11B1;CYP1A1;CYP2C9;CYP17A1;CYP3A5;CYP2D6;CYP2C19;CYP1B1 GO:0006704| glucocorticoid biosynthetic process CYP17A1;HSD11B1 21187:[DB14011 DB02555] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB02555|SP4160 IL2 common genes common pathways GO:0045471| response to ethanol HMGCR;OPRM1;CNR1;SOD1;CAT;IL2 GO:0006955| immune response IL2;OPRD1;CNR2 GO:0030217| T cell differentiation GPR18;IL2 GO:0001934| positive regulation of protein phosphorylation IL2;CHRNA7 GO:0065009| regulation of molecular function TRPV1;IL2 GO:0050729| positive regulation of inflammatory response IL2;TRPV4 GO:0007204| elevation of cytosolic calcium ion concentration OPRM1;HTR2A;TRPV4;TRPV1;IL2 GO:0043066| negative regulation of apoptotic process IL2;GPX1;CAT;HMGCR;PTGS2;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;PLA2G1B;PPARG GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;IL2 GO:0007155| cell adhesion CYP1B1;IL2 GO:0050728| negative regulation of inflammatory response IL2;CNR2 GO:0002376| immune system process IDO1;IL2 GO:0007186| G-protein coupled receptor signaling pathway IL2;GPR18;PPARG;OPRD1;OPRM1;CNR2;HTR2A;CNR1;GPR12;HTR1A;GPR55 21188:[DB14011 DB08891] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GABBR2;GABBR1;OPRM1;CNR2;OPRD1;GPR55;HTR1A;CNR1;GPR12;HTR2A GO:0007165| signal transduction PLA2G1B;CACNA1I;GABBR2;SMPD1;PPARG;GPR18;CHRNA7;OPRM1;GABBR1;CNR2;OPRD1;HTR1A;GPR55;HTR2A;CNR1;GPR12 GO:0007193| inhibition of adenylate cyclase activity by G-protein signaling pathway OPRD1;OPRM1;GABBR1 GO:0007268| synaptic transmission GABBR2;GLRB;VDAC1;GLRA1;CACNA1G;GLRA3;HTR2A;OPRD1;OPRM1 GO:0007194| negative regulation of adenylate cyclase activity OPRM1;GABBR1;GABBR2 21189:[DB14011 DB08618] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08618|3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER IGHG2 common genes common pathways GO:0045087| innate immune response IGHG2;PPARG GO:0002376| immune system process IGHG2;IDO1 21190:[DB14011 DB11674] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB11674|Equol ESR2;SHBG common genes common pathways GO:0007165| signal transduction CHRNA7;HTR2A;GPR12;CNR1;GPR55;HTR1A;OPRD1;OPRM1;CNR2;ESR2;PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1 GO:0043401| steroid hormone mediated signaling pathway ESR2;PPARG GO:0006351| transcription, DNA-dependent ESR2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;ESR2 GO:0030308| negative regulation of cell growth ESR2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;PLA2G1B;PPARG GO:0000122| negative regulation of transcription from RNA polymerase II promoter PPARG;ESR2;TRPV1;TRPV4 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;PPARG GO:0006355| regulation of transcription, DNA-dependent ESR2;PPARG GO:0006367| transcription initiation from RNA polymerase II promoter ESR2;PPARG 21191:[DB14011 DB01884] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CYP1B1 GO:0008284| positive regulation of cell proliferation DPP4;HTR2A;HTR1A;HMGCR;PTGS2;CHRNA7 GO:0043542| endothelial cell migration DPP4;CYP1B1 GO:0001666| response to hypoxia CAT;CHRNA7;DPP4;CYP1A1 GO:0001662| behavioral fear response DPP4;VDAC1;HTR1A GO:0050796| regulation of insulin secretion DPP4;CNR1 GO:0046718| entry of virus into host cell DPP4;HTR2A 21192:[DB14011 DB07913] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07913|HOMOPHENYLALANINYLMETHANE CTSF common genes common pathways 21193:[DB14011 DB04677] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04677|N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE MAOB common genes common pathways GO:0050665| hydrogen peroxide biosynthetic process SOD1;CYP1A2;CYP1A1;MAOB GO:0022900| electron transport chain GSR;IDO1;MAOB;CYP1A2 GO:0042493| response to drug ABCG2;ABCC1;SMPD1;MAOB;TRPA1;PPARG;CYP1A1;CAT;PTGS2;CYP1A2;HTR2A;SOD1 GO:0055114| oxidation-reduction process MAOB;CRYZ;CYP1A1;CYP2C9;CYP1B1;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;GPX1;ALOX5;PTGS1;CAT GO:0032496| response to lipopolysaccharide CNR1;CYP1A2;OPRM1;CNR2;PTGS2;CYP1A1;MAOB;IDO1 GO:0010269| response to selenium ion MAOB;GPX1 GO:0009636| response to toxin CAT;GPX1;CYP1B1;CYP1A1;MAOB GO:0051412| response to corticosterone stimulus AANAT;MAOB GO:0045471| response to ethanol MAOB;CAT;CNR1;SOD1;OPRM1;HMGCR 21194:[DB14011 DB01060] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01060|Amoxicillin CYP2C19;SLC15A1;SLC15A2;SLC22A6 common genes CYP2C19 common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CRYZ;CYP1B1;CYP3A5;ALOX15;CYP17A1;IDO1;GSR;CYP2C19;CYP2D6;CYP1A2;PTGS2;CYP3A7;HMGCR;CYP3A4;SOD1;ALOX5;GPX1;PTGS1;CAT GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0055085| transmembrane transport TRPV3;CACNA1H;SLC15A2;TRPV2;ABCC1;CACNA1G;SLC22A6;TRPA1;SLC15A1;VDAC1;CACNA1I;TRPV4;TRPV1;TRPM8;ABCG2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP3A5;CYP17A1;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;HMGCR GO:0006810| transport SLC15A2;TRPV2;ABCC1;SLC15A1;TRPV1;CACNA1I;ABCG2 GO:0051260| protein homooligomerization GLRA3;ACAT1;SLC22A6;GLRA1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C19 GO:0006820| anion transport VDAC1;GLRA1;SLC22A6 GO:0042738| exogenous drug catabolic process CYP1A2;CYP3A4;CYP2C19;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP3A7;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0006811| ion transport CHRNA7;TRPV2;SLC15A2;GLRA3;TRPV3;CACNA1H;TRPM8;VDAC1;CACNA1I;TRPV4;GLRB;TRPV1;TRPA1;GLRA1;SLC15A1;CACNA1G GO:0098656| SLC22A6;VDAC1 GO:0097267| CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP1A2 21195:[DB14011 DB06160] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB06160|Garenoxacin CYP1A2 common genes CYP1A2 common pathways GO:0042738| exogenous drug catabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4 GO:0009403| toxin biosynthetic process CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C19;CYP1B1;CYP3A4;CYP3A7;CYP1A2;PTGS1 GO:0006778| porphyrin-containing compound metabolic process CYP1A1;CYP1A2 GO:0006706| steroid catabolic process CYP1A2;CYP3A4 GO:0006629| lipid metabolic process NAPEPLD;CYP3A4;PTGS2;CYP1A2;HMGCR;NAAA;PTGS1;GPX1;CYP2C9;PPARG;ALOX15;CYP2D6;DAGLA;TRPV1;PLA2G1B GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A1;AANAT;ACAT1;CYP1A2;PTGS2 GO:0045333| cellular respiration CYP1A2 GO:0009820| alkaloid metabolic process CYP1A2;CYP2D6 GO:0006725| cellular aromatic compound metabolic process CYP1B1;CYP1A2 GO:0009791| post-embryonic development CYP1A2 GO:0071276| cellular response to cadmium ion SOD1;CYP1A2 GO:0070989| oxidative demethylation CYP1A2;CYP3A4;CYP2D6;CYP3A5;CYP2C9 GO:0097267| CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP1A2 GO:0022900| electron transport chain IDO1;GSR;CYP1A2 GO:0042493| response to drug ABCG2;PPARG;CYP1A1;TRPA1;SMPD1;ABCC1;CAT;HTR2A;SOD1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CAT;PTGS1;ALOX5;GPX1;SOD1;CYP3A4;HMGCR;PTGS2;CYP3A7;CYP1A2;CYP2D6;IDO1;GSR;CYP2C19;CYP3A5;ALOX15;CYP17A1;CYP1B1;CRYZ;CYP1A1;CYP2C9 GO:0032496| response to lipopolysaccharide CYP1A1;IDO1;CNR1;CNR2;PTGS2;OPRM1;CYP1A2 GO:0042737| drug catabolic process CYP3A5;CYP2D6;CYP2C9;CYP3A4;CYP1A2 GO:0030324| lung development CYP1A2 GO:0018894| dibenzo-p-dioxin metabolic process CYP1A2;CYP1A1 GO:0032259| methylation CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C9;CYP1A1;CYP1A2 GO:0035902| response to immobilization stress PPARG;CYP1A1;CYP1A2 GO:0071615| oxidative deethylation CYP1A2 GO:0050665| hydrogen peroxide biosynthetic process CYP1A1;CYP1A2;SOD1 GO:0009404| toxin metabolic process CYP1B1;CYP1A1;CYP1A2 GO:0010033| response to organic substance CYP1A1;PPARG;TRPA1;CYP1A2;PTGS2;SOD1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP17A1;CYP2C19;CYP2D6;CYP1A2;CYP3A7;HMGCR;CYP3A4 GO:0032787| monocarboxylic acid metabolic process CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;CAT GO:0010468| regulation of gene expression CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP1A2 GO:0071280| cellular response to copper ion CYP1A2;CYP1A1 21196:[DB14011 DB04079] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB04079|Heptane-1,2,3-Triol RHO common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;GPR18;PPARG;SMPD1;RHO;CHRNA7;GPR12;CNR1;HTR2A;HTR1A;GPR55;OPRD1;OPRM1;CNR2 GO:0007601| visual perception RHO;CRYZ;GLRA1;CYP1B1;GLRB GO:0050896| response to stimulus TRPM8;TRPA1;RHO GO:0001523| retinoid metabolic process RHO;NAPEPLD GO:0007186| G-protein coupled receptor signaling pathway HTR1A;GPR55;GPR12;CNR1;HTR2A;CNR2;OPRM1;OPRD1;PPARG;GPR18;RHO GO:0009416| response to light stimulus RHO;AANAT 21197:[DB14011 DB03087] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03087|2-(Sec-Butyl)Thiazole LCN9 common genes common pathways 21198:[DB14011 DB08855] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB08855|Leukotriene C4 CYSLTR1;CYSLTR2;ABCC1;SLCO1B1;SLCO1B3 common genes ABCC1 common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;PLA2G1B;CYSLTR1;CACNA1I;HTR1A;GPR55;CYSLTR2;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1;CHRNA7 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0007204| elevation of cytosolic calcium ion concentration TRPV1;CYSLTR1;TRPV4;HTR2A;OPRM1 GO:0006811| ion transport CACNA1I;TRPV4;GLRB;VDAC1;TRPV1;TRPM8;CACNA1G;GLRA1;TRPA1;TRPV2;CHRNA7;CACNA1H;TRPV3;SLCO1B3;GLRA3;SLCO1B1 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0034775| glutathione transmembrane transport ABCC1 GO:0007166| cell surface receptor linked signaling pathway TRPA1;CYSLTR1;TRPV1 GO:0006955| immune response CYSLTR2;OPRD1;CNR2 GO:0006816| calcium ion transport TRPV2;CHRNA7;CACNA1H;TRPV3;CACNA1I;TRPV4;TRPV1;CYSLTR1;TRPM8;CACNA1G;TRPA1 GO:0010942| positive regulation of cell death CYSLTR2;PTGS2 GO:0007186| G-protein coupled receptor signaling pathway OPRD1;CNR2;OPRM1;HTR2A;GPR12;CNR1;CYSLTR2;GPR55;HTR1A;GPR18;PPARG;CYSLTR1 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport TRPV1;CACNA1I;ABCG2;ABCC1;TRPV2 GO:0045766| positive regulation of angiogenesis CYSLTR2;CHRNA7;CYP1B1 GO:0070374| positive regulation of ERK1 and ERK2 cascade CHRNA7;GPR55;CYSLTR2;HTR2A;OPRM1;HMGCR;ALOX15;TRPV4 GO:0055085| transmembrane transport CACNA1G;ABCC1;TRPA1;TRPV1;TRPV4;CACNA1I;VDAC1;ABCG2;TRPM8;CACNA1H;TRPV3;SLCO1B3;SLCO1B1;TRPV2 GO:0007218| neuropeptide signaling pathway GLRA1;CYSLTR1;GLRB;OPRM1;OPRD1;CYSLTR2;GLRA3 GO:0007200| activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger CYSLTR1;OPRD1;OPRM1;HTR2A;CYSLTR2 GO:0060326| cell chemotaxis ABCC1 GO:0099133| ABCC1 GO:0042493| response to drug PTGS2;CYP1A2;HTR2A;SOD1;CAT;ABCC1;SMPD1;PPARG;CYP1A1;TRPA1;ABCG2 GO:0006691| leukotriene metabolic process ALOX15;ABCC1;ALOX5 21199:[DB14011 DB03881] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03881|MT-Immucillin-H PNP common genes common pathways GO:0006955| immune response PNP;OPRD1;CNR2 GO:0006195| purine nucleotide catabolic process PNP;GPX1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006139| nucleobase-containing compound metabolic process PNP;SLC29A1 GO:0043312| neutrophil degranulation CAT;ALOX5;PNP GO:0042493| response to drug TRPA1;CYP1A1;PNP;PPARG;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A2;PTGS2;CAT 21200:[DB14011 DB01276] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01276|Exenatide GLP1R;ALB common genes common pathways GO:0007165| signal transduction PLA2G1B;CACNA1I;SMPD1;GLP1R;GPR18;PPARG;CHRNA7;OPRD1;OPRM1;CNR2;GPR12;CNR1;HTR2A;HTR1A;GPR55 GO:0007204| elevation of cytosolic calcium ion concentration GLP1R;TRPV1;TRPV4;HTR2A;OPRM1 GO:0050796| regulation of insulin secretion CNR1;GLP1R GO:0001895| retina homeostasis SOD1;ALB GO:0045777| positive regulation of blood pressure CNR1;GLP1R GO:0008016| regulation of heart contraction CACNA1H;GLP1R GO:0007166| cell surface receptor linked signaling pathway TRPV1;TRPA1;GLP1R GO:0098869| ALB;GSR;PTGS2;CAT;GPX1;PTGS1 GO:0007186| G-protein coupled receptor signaling pathway PPARG;GPR18;GLP1R;HTR1A;GPR55;HTR2A;GPR12;CNR1;OPRM1;CNR2;OPRD1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process SOD1;HMGCR;PTGS2;CAT;GPX1;ALB GO:0007611| learning or memory CHRNA7;CNR1;GLP1R 21201:[DB14011 DB14040] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB14040|Eptinezumab CALCA;CALCB common genes common pathways GO:0007165| signal transduction PPARG;GPR18;SMPD1;CALCB;CACNA1I;PLA2G1B;GPR55;HTR1A;HTR2A;GPR12;CNR1;CNR2;OPRM1;OPRD1;CHRNA7 GO:0008217| regulation of blood pressure PTGS2;SOD1;PTGS1;CALCA;PPARG GO:0061844| PLA2G1B;CALCA GO:0045776| negative regulation of blood pressure CALCA;CNR1 GO:0007186| G-protein coupled receptor signaling pathway CALCB;PPARG;CALCA;GPR18;GPR55;HTR1A;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1 GO:0006874| cellular calcium ion homeostasis CHRNA7;HTR2A;GPR12;TRPV4;CALCB;TRPM8 GO:0045671| negative regulation of osteoclast differentiation GPR55;CALCA GO:0051482| elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger GPR55;CALCA;GPR18 GO:0043542| endothelial cell migration CALCA;CYP1B1 GO:0045087| innate immune response PPARG;CALCA GO:0019731| antibacterial humoral response PLA2G1B;CALCA GO:0050830| defense response to Gram-positive bacterium PLA2G1B;CALCA 21202:[DB14011 DB01949] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways GO:0001934| positive regulation of protein phosphorylation CHRNA7;MMP9 GO:0043065| positive regulation of apoptotic process PTGS2;SOD1;CNR1;SMPD1;PPARG;MMP9;CYP1B1;TRPV1;IDO1 GO:0001503| ossification ALOX15;MMP9 GO:0071276| cellular response to cadmium ion MMP9;CYP1A2;SOD1 GO:0007566| embryo implantation MMP9;PTGS2;SOD1 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2;SOD1;GPX1;CAT;MMP9 GO:0043312| neutrophil degranulation MMP9;ALOX5;CAT GO:0043388| positive regulation of DNA binding PPARG;MMP9 21203:[DB14011 DB05217] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB05217|GMX1777 NAMPT common genes common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;NAMPT GO:0007165| signal transduction PPARG;GPR18;SMPD1;NAMPT;CACNA1I;PLA2G1B;HTR1A;GPR55;HTR2A;CNR1;GPR12;CNR2;OPRM1;OPRD1;CHRNA7 GO:0014070| response to organic cyclic compound NAMPT;TRPA1;CYP1A1;PPARG;AANAT;ACAT1;CYP1A2;PTGS2 GO:0060612| adipose tissue development NAMPT;ACAT1 GO:0007565| female pregnancy NAMPT;IDO1 GO:0048511| rhythmic process PPARG;NAMPT;AANAT GO:0007623| circadian rhythm NAMPT;AANAT GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2;HTR2A;HTR1A;CHRNA7;NAMPT GO:0045944| positive regulation of transcription from RNA polymerase II promoter NAMPT;PLA2G1B;PPARG GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2;NAMPT 21204:[DB14011 DB07601] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB07601|4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol HSP90AA1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1;HSP90AA1;TRPV1 GO:0046677| response to antibiotic HSP90AA1;CYP1A1;SOD1 GO:0043312| neutrophil degranulation HSP90AA1;ALOX5;CAT GO:0007165| signal transduction CHRNA7;OPRD1;CNR2;OPRM1;HTR2A;CNR1;GPR12;GPR55;HTR1A;CACNA1I;PLA2G1B;SMPD1;GPR18;HSP90AA1;PPARG GO:0009408| response to heat HSP90AA1;TRPV1;SOD1;TRPV3;TRPV2 GO:0009409| response to cold TRPA1;PPARG;HSP90AA1;TRPM8 21205:[DB14011 DB03632] DB14011|Nabiximols CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 DB03632|Argifin CHIT1 common genes common pathways GO:0006955| immune response CNR2;OPRD1;CHIT1 GO:0008152| metabolic process ACAT1;CHIT1;SMPD1 GO:0043312| neutrophil degranulation CHIT1;ALOX5;CAT 21206:[DB00027 DB07543] DB00027|Gramicidin D ABCB1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways 21207:[DB00027 DB11730] DB00027|Gramicidin D ABCB1 DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;ABCB1 21208:[DB00027 DB00413] DB00027|Gramicidin D ABCB1 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0042493| response to drug DRD3;HTR2C;HTR2B;HTR1B;ABCB1;DRD2;HTR2A;DRD1 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCB1 21209:[DB00027 DB03685] DB00027|Gramicidin D ABCB1 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways 21210:[DB00027 DB01179] DB00027|Gramicidin D ABCB1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBA4A;TUBB 21211:[DB00027 DB05127] DB00027|Gramicidin D ABCB1 DB05127|ANA971 TLR7 common genes common pathways 21212:[DB00027 DB03372] DB00027|Gramicidin D ABCB1 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways 21213:[DB00027 DB01148] DB00027|Gramicidin D ABCB1 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways 21214:[DB00027 DB01594] DB00027|Gramicidin D ABCB1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1 GO:0006810| transport GABRD;GABRB2;GABRR2;GABRA5;GABRA3;ABCB1;GABRR1;GABRA1;GABRG2;GABRB1;GABRB3 21215:[DB00027 DB00645] DB00027|Gramicidin D ABCB1 DB00645|Dyclonine SCN10A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN10A 21216:[DB00027 DB09213] DB00027|Gramicidin D ABCB1 DB09213|Dexibuprofen PTGS2;PTGS1;BCL2;THBD;PLAT;FABP2;PPARG;CFTR;SLC15A1;PPARA;GP1BA;S100A7;CYP2C9;UGT1A1;UGT1A3;UGT1A9;UGT2B4;UGT2B7;CYP2C8;CYP2C19;AMACR;ALB;ABCC4;ABCC1;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLCO2B1;ABCB1 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;PPARG;UGT1A1;ABCC1;ABCC4;PTGS2;BCL2 GO:0006810| transport ABCB1;ABCC1;SLC15A1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport BCL2;SLCO1A2;SLC22A8;ABCC4;SLC22A11;ABCC1;SLC22A6;CFTR;SLC15A1;ABCB1;SLCO2B1 21217:[DB00027 DB06725] DB00027|Gramicidin D ABCB1 DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 21218:[DB00027 DB04863] DB00027|Gramicidin D ABCB1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways 21219:[DB00027 DB00232] DB00027|Gramicidin D ABCB1 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0006810| transport SLC12A1;ABCB1 GO:0055085| transmembrane transport SLC12A1;ABCB1 21220:[DB00027 DB01580] DB00027|Gramicidin D ABCB1 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0055085| transmembrane transport SLC22A2;ABCB1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 21221:[DB00027 DB00725] DB00027|Gramicidin D ABCB1 DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways 21222:[DB00027 DB00838] DB00027|Gramicidin D ABCB1 DB00838|Clocortolone NR3C1 common genes common pathways 21223:[DB00027 DB06935] DB00027|Gramicidin D ABCB1 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR 21224:[DB00027 DB02789] DB00027|Gramicidin D ABCB1 DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC10A6 GO:0042908| xenobiotic transport ABCB1;NR1I2 21225:[DB00027 DB08911] DB00027|Gramicidin D ABCB1 DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways 21226:[DB00027 DB00087] DB00027|Gramicidin D ABCB1 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 21227:[DB00027 DB01415] DB00027|Gramicidin D ABCB1 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0055085| transmembrane transport SLC15A1;SLC22A6;ABCB1;SLC15A2;SLC22A8 21228:[DB00027 DB06803] DB00027|Gramicidin D ABCB1 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21229:[DB00027 DB06914] DB00027|Gramicidin D ABCB1 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways 21230:[DB00027 DB00940] DB00027|Gramicidin D ABCB1 DB00940|Methantheline CHRM1;HRH2 common genes common pathways 21231:[DB00027 DB01837] DB00027|Gramicidin D ABCB1 DB01837|O-acetyl-L-serine PTGS1 common genes common pathways 21232:[DB00027 DB09422] DB00027|Gramicidin D ABCB1 DB09422|Soybean oil PPARA common genes common pathways 21233:[DB00027 DB00098] DB00027|Gramicidin D ABCB1 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways 21234:[DB00027 DB03245] DB00027|Gramicidin D ABCB1 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways 21235:[DB00027 DB00816] DB00027|Gramicidin D ABCB1 DB00816|Orciprenaline ADRB2 common genes common pathways 21236:[DB00027 DB04185] DB00027|Gramicidin D ABCB1 DB04185|Norvaline OTC;GATM common genes common pathways GO:0042493| response to drug OTC;ABCB1 21237:[DB00027 DB08962] DB00027|Gramicidin D ABCB1 DB08962|Glibornuride CYP2C9 common genes common pathways 21238:[DB00027 DB00936] DB00027|Gramicidin D ABCB1 DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 GO:0055085| transmembrane transport SLC22A6;SLC22A10;ABCB1;SLCO2B1;SLC22A8;SLC22A7;SLC16A1;SLC22A11 21239:[DB00027 DB01165] DB00027|Gramicidin D ABCB1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2;SLC22A5 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0042493| response to drug CYP1A2;ABCC2;ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB11;SLC22A5;SLC22A4;SLC22A6;ABCC1;ABCC2;ABCB1 GO:0006810| transport ABCC1;ABCB1;ABCC2;ABCB11 21240:[DB00027 DB00671] DB00027|Gramicidin D ABCB1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2;SLC22A5 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 21241:[DB00027 DB06685] DB00027|Gramicidin D ABCB1 DB06685|Laquinimod CYP3A4 common genes common pathways 21242:[DB00027 DB01959] DB00027|Gramicidin D ABCB1 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways 21243:[DB00027 DB01618] DB00027|Gramicidin D ABCB1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;HTR2A 21244:[DB00027 DB08894] DB00027|Gramicidin D ABCB1 DB08894|Peginesatide EPOR common genes common pathways 21245:[DB00027 DB07546] DB00027|Gramicidin D ABCB1 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways 21246:[DB00027 DB05111] DB00027|Gramicidin D ABCB1 DB05111|Fontolizumab IFNG common genes common pathways 21247:[DB00027 DB00617] DB00027|Gramicidin D ABCB1 DB00617|Paramethadione CACNA1I;CYP2E1;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055085| transmembrane transport CACNA1I;ABCB1 GO:0006810| transport CACNA1I;ABCB1 21248:[DB00027 DB03600] DB00027|Gramicidin D ABCB1 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes common pathways GO:0042493| response to drug PPARG;ABCB1 21249:[DB00027 DB01029] DB00027|Gramicidin D ABCB1 DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;JUN 21250:[DB00027 DB01436] DB00027|Gramicidin D ABCB1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways 21251:[DB00027 DB00681] DB00027|Gramicidin D ABCB1 DB00681|Amphotericin B CYP3A4 common genes common pathways 21252:[DB00027 DB00866] DB00027|Gramicidin D ABCB1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways 21253:[DB00027 DB08256] DB00027|Gramicidin D ABCB1 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways 21254:[DB00027 DB06233] DB00027|Gramicidin D ABCB1 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways 21255:[DB00027 DB07830] DB00027|Gramicidin D ABCB1 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways 21256:[DB00027 DB00843] DB00027|Gramicidin D ABCB1 DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;HTR2A 21257:[DB00027 DB11785] DB00027|Gramicidin D ABCB1 DB11785|Anisodamine CYP2D6 common genes common pathways 21258:[DB00027 DB12450] DB00027|Gramicidin D ABCB1 DB12450|Propyl Gallate ESR1 common genes common pathways 21259:[DB00027 DB05258] DB00027|Gramicidin D ABCB1 DB05258|Natural alpha interferon IFNAR1 common genes common pathways 21260:[DB00027 DB08936] DB00027|Gramicidin D ABCB1 DB08936|Chlorcyclizine HRH1 common genes common pathways 21261:[DB00027 DB09160] DB00027|Gramicidin D ABCB1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0006810| transport ABCB1 21262:[DB00027 DB12872] DB00027|Gramicidin D ABCB1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0042493| response to drug COL1A1;ABCB1 21263:[DB00027 DB09371] DB00027|Gramicidin D ABCB1 DB09371|Norethynodrel ESR1;AR;SHBG;CYP3A4 common genes common pathways GO:0006810| transport ABCB1;AR 21264:[DB00027 DB00135] DB00027|Gramicidin D ABCB1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0006810| transport ABCB1;SLC16A2 GO:0055085| transmembrane transport SLC16A10;SLC16A2;ABCB1 GO:0042493| response to drug TH;ABCB1 21265:[DB00027 DB02340] DB00027|Gramicidin D ABCB1 DB02340|N-Acetyl-Serine F13A1 common genes common pathways 21266:[DB00027 DB06477] DB00027|Gramicidin D ABCB1 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways GO:0042493| response to drug DRD3;DRD2;ABCB1 21267:[DB00027 DB08877] DB00027|Gramicidin D ABCB1 DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways 21268:[DB00027 DB02483] DB00027|Gramicidin D ABCB1 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0042493| response to drug ABCB1;LDHA 21269:[DB00027 DB07092] DB00027|Gramicidin D ABCB1 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways 21270:[DB00027 DB00654] DB00027|Gramicidin D ABCB1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLC22A1 21271:[DB00027 DB04363] DB00027|Gramicidin D ABCB1 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways 21272:[DB00027 DB00292] DB00027|Gramicidin D ABCB1 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;SLC2A1 GO:0042493| response to drug ABCB1;GABRG3 GO:0006810| transport GABRB3;GABRB1;GABRG2;GABRA4;GABRA6;GABRA1;ABCB1;GABRA5;GABRA3;GABRD;GABRB2 GO:0055085| transmembrane transport ABCB1;SLC2A1 21273:[DB00027 DB01218] DB00027|Gramicidin D ABCB1 DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCB1 21274:[DB00027 DB00263] DB00027|Gramicidin D ABCB1 DB00263|Sulfisoxazole CYP2C9 common genes common pathways 21275:[DB00027 DB01099] DB00027|Gramicidin D ABCB1 DB01099|Flucytosine DNMT1 common genes common pathways 21276:[DB00027 DB02857] DB00027|Gramicidin D ABCB1 DB02857|Guanosine PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 21277:[DB00027 DB06267] DB00027|Gramicidin D ABCB1 DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways 21278:[DB00027 DB06660] DB00027|Gramicidin D ABCB1 DB06660|Saredutant TACR2 common genes common pathways 21279:[DB00027 DB09090] DB00027|Gramicidin D ABCB1 DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CACNA1S;ABCB1 21280:[DB00027 DB00139] DB00027|Gramicidin D ABCB1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0042493| response to drug OXCT1;ABCB1 GO:0006810| transport ABCB1;SLC13A2 GO:0055085| transmembrane transport ABCB1;SLC13A2;SLC13A1;SLC13A3;SLC22A8 21281:[DB00027 DB02110] DB00027|Gramicidin D ABCB1 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways 21282:[DB00027 DB01854] DB00027|Gramicidin D ABCB1 DB01854|5-Bromonicotinamide ART1 common genes common pathways 21283:[DB00027 DB06156] DB00027|Gramicidin D ABCB1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A2;ABCB1;SLC6A3;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A4;SLC6A2;SLC6A3;ABCB1 21284:[DB00027 DB09016] DB00027|Gramicidin D ABCB1 DB09016|Butriptyline SLC6A4;HRH1;HTR2A common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0042493| response to drug ABCB1;SLC6A4;HTR2A 21285:[DB00027 DB01430] DB00027|Gramicidin D ABCB1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 21286:[DB00027 DB06701] DB00027|Gramicidin D ABCB1 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A3;SLC6A2;SLC6A4 GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCB1;SLC6A3 GO:0006810| transport SLC6A2;ABCB1 21287:[DB00027 DB13164] DB00027|Gramicidin D ABCB1 DB13164|Olmutinib EGFR common genes common pathways 21288:[DB00027 DB01198] DB00027|Gramicidin D ABCB1 DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0006810| transport GABRA3;GABRA5;ABCB1;GABRA1 GO:0042493| response to drug CYP2E1;TSPO;ABCB1 21289:[DB00027 DB09334] DB00027|Gramicidin D ABCB1 DB09334|Seractide acetate MC2R common genes common pathways 21290:[DB00027 DB03752] DB00027|Gramicidin D ABCB1 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways 21291:[DB00027 DB04017] DB00027|Gramicidin D ABCB1 DB04017|Clorgiline MAOA common genes common pathways 21292:[DB00027 DB00854] DB00027|Gramicidin D ABCB1 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways 21293:[DB00027 DB04614] DB00027|Gramicidin D ABCB1 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways 21294:[DB00027 DB00493] DB00027|Gramicidin D ABCB1 DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport SLC22A11;SLC22A7;SLC22A8;SLC15A2;ABCB1;SLC22A6;SLC15A1 21295:[DB00027 DB06848] DB00027|Gramicidin D ABCB1 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways 21296:[DB00027 DB08695] DB00027|Gramicidin D ABCB1 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways 21297:[DB00027 DB14050] DB00027|Gramicidin D ABCB1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0006810| transport TRPV2;ABCB1;TRPV1 GO:0055085| transmembrane transport TRPV1;ABCB1;TRPA1;TRPV2 GO:0042493| response to drug ABCB1;TRPA1 21298:[DB00027 DB01245] DB00027|Gramicidin D ABCB1 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE 21299:[DB00027 DB05785] DB00027|Gramicidin D ABCB1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0042493| response to drug JUN;ABCB1 21300:[DB00027 DB00119] DB00027|Gramicidin D ABCB1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0042493| response to drug ABCB1;ABAT GO:0006810| transport ABCB1;SLC16A2 GO:0055085| transmembrane transport SLC16A2;SLC16A1;SLC16A10;SLC16A7;SLC16A4;ABCB1;SLC16A5;SLC16A8;SLCO2A1;SLC16A6;SLC16A3 21301:[DB00027 DB02623] DB00027|Gramicidin D ABCB1 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways 21302:[DB00027 DB01805] DB00027|Gramicidin D ABCB1 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways 21303:[DB00027 DB11201] DB00027|Gramicidin D ABCB1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 21304:[DB00027 DB00370] DB00027|Gramicidin D ABCB1 DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0042493| response to drug DRD3;SLC6A2;HTR2C;HTR2B;SLC6A3;DRD2;ADRA1A;ABCB1;HTR2A;CYP1A2;SLC6A4;DRD1 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3;SLC6A4 21305:[DB00027 DB02418] DB00027|Gramicidin D ABCB1 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways 21306:[DB00027 DB00392] DB00027|Gramicidin D ABCB1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE 21307:[DB00027 DB08632] DB00027|Gramicidin D ABCB1 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways 21308:[DB00027 DB09559] DB00027|Gramicidin D ABCB1 DB09559|Necitumumab EGFR common genes common pathways 21309:[DB00027 DB00775] DB00027|Gramicidin D ABCB1 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways 21310:[DB00027 DB00768] DB00027|Gramicidin D ABCB1 DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways 21311:[DB00027 DB00483] DB00027|Gramicidin D ABCB1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways 21312:[DB00027 DB07297] DB00027|Gramicidin D ABCB1 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways GO:0042493| response to drug LCK;ABCB1 21313:[DB00027 DB00802] DB00027|Gramicidin D ABCB1 DB00802|Alfentanil OPRM1;CYP3A4;CYP3A7;CYP3A5;ORM1;ALB;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 21314:[DB00027 DB00416] DB00027|Gramicidin D ABCB1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways 21315:[DB00027 DB01036] DB00027|Gramicidin D ABCB1 DB01036|Tolterodine CHRM3;CHRM2;CHRM5;CHRM1;CHRM4;CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways 21316:[DB00027 DB01914] DB00027|Gramicidin D ABCB1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0055085| transmembrane transport SLC2A8;SLC2A1;SLC2A12;SLC2A9;SLC2A3;SLC2A6;SLC5A1;SLC2A7;SLC2A11;SLC2A4;SLC5A2;ABCB1;SLC2A10;SLC2A2;SLC2A5 GO:0006810| transport SLC5A2;ABCB1 GO:0042908| xenobiotic transport ABCB1;SLC2A1 21317:[DB00027 DB04005] DB00027|Gramicidin D ABCB1 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways 21318:[DB00027 DB06506] DB00027|Gramicidin D ABCB1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways 21319:[DB00027 DB00063] DB00027|Gramicidin D ABCB1 DB00063|Eptifibatide ITGB3 common genes common pathways 21320:[DB00027 DB00149] DB00027|Gramicidin D ABCB1 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10;SLC16A2 GO:0000086| G2/M transition of mitotic cell cycle LCMT1;ABCB1 GO:0006810| transport SLC16A2;ABCB1 21321:[DB00027 DB08251] DB00027|Gramicidin D ABCB1 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways GO:0042493| response to drug CASP3;ABCB1 21322:[DB00027 DB00960] DB00027|Gramicidin D ABCB1 DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;HTR1B 21323:[DB00027 DB01917] DB00027|Gramicidin D ABCB1 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A4 21324:[DB00027 DB03256] DB00027|Gramicidin D ABCB1 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways 21325:[DB00027 DB08486] DB00027|Gramicidin D ABCB1 DB08486|Efaproxiral HBA1;HBB common genes common pathways 21326:[DB00027 DB08302] DB00027|Gramicidin D ABCB1 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 21327:[DB00027 DB07842] DB00027|Gramicidin D ABCB1 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 21328:[DB00027 DB09273] DB00027|Gramicidin D ABCB1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;ADORA2A;CYP1A2 21329:[DB00027 DB05308] DB00027|Gramicidin D ABCB1 DB05308|ANX-510 TYMS common genes common pathways GO:0042493| response to drug TYMS;ABCB1 21330:[DB00027 DB00290] DB00027|Gramicidin D ABCB1 DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0042493| response to drug ABCB1;BLMH 21331:[DB00027 DB00732] DB00027|Gramicidin D ABCB1 DB00732|Atracurium besylate CHRNA2 common genes common pathways 21332:[DB00027 DB07302] DB00027|Gramicidin D ABCB1 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 21333:[DB00027 DB02166] DB00027|Gramicidin D ABCB1 DB02166|Propidium ACHE common genes common pathways 21334:[DB00027 DB14597] DB00027|Gramicidin D ABCB1 DB14597|Lanadelumab KLKB1 common genes common pathways 21335:[DB00027 DB07047] DB00027|Gramicidin D ABCB1 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR 21336:[DB00027 DB09517] DB00027|Gramicidin D ABCB1 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways 21337:[DB00027 DB07144] DB00027|Gramicidin D ABCB1 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 21338:[DB00027 DB06739] DB00027|Gramicidin D ABCB1 DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0042493| response to drug ABCB1;TBXA2R 21339:[DB00027 DB00296] DB00027|Gramicidin D ABCB1 DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 GO:0055085| transmembrane transport SCN10A;ABCB1 21340:[DB00027 DB07670] DB00027|Gramicidin D ABCB1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways 21341:[DB00027 DB01079] DB00027|Gramicidin D ABCB1 DB01079|Tegaserod HTR4;HTR2B;HTR2C;HTR2A;CYP1A2;CYP2C8;CYP2D6;CYP2E1;SLC6A4 common genes common pathways GO:0055085| transmembrane transport SLC6A4;ABCB1 GO:0042493| response to drug SLC6A4;HTR2A;CYP2E1;CYP1A2;HTR2B;HTR2C;ABCB1 21342:[DB00027 DB06247] DB00027|Gramicidin D ABCB1 DB06247|CX516 GRIA1 common genes common pathways 21343:[DB00027 DB07740] DB00027|Gramicidin D ABCB1 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways GO:0042493| response to drug ABCB1;HMGCS1 21344:[DB00027 DB02404] DB00027|Gramicidin D ABCB1 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways 21345:[DB00027 DB04469] DB00027|Gramicidin D ABCB1 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 21346:[DB00027 DB01124] DB00027|Gramicidin D ABCB1 DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC8 GO:0055085| transmembrane transport SLC15A1;SLC22A6;SLCO2B1;ABCB1;ABCC8;SLC15A2;SLCO1A2 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 21347:[DB00027 DB06530] DB00027|Gramicidin D ABCB1 DB06530|Resiquimod TLR7;TLR8 common genes common pathways 21348:[DB00027 DB06607] DB00027|Gramicidin D ABCB1 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways 21349:[DB00027 DB04801] DB00027|Gramicidin D ABCB1 DB04801|cis-Vaccenic acid PPARD common genes common pathways 21350:[DB00027 DB09421] DB00027|Gramicidin D ABCB1 DB09421|Protirelin TRHR common genes common pathways 21351:[DB00027 DB00046] DB00027|Gramicidin D ABCB1 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways 21352:[DB00027 DB13783] DB00027|Gramicidin D ABCB1 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1;PTGS2 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 21353:[DB00027 DB00800] DB00027|Gramicidin D ABCB1 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1;DRD1 21354:[DB00027 DB05676] DB00027|Gramicidin D ABCB1 DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways 21355:[DB00027 DB07282] DB00027|Gramicidin D ABCB1 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 21356:[DB00027 DB02427] DB00027|Gramicidin D ABCB1 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways 21357:[DB00027 DB06694] DB00027|Gramicidin D ABCB1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 21358:[DB00027 DB05289] DB00027|Gramicidin D ABCB1 DB05289|Tarenflurbil IKBKG common genes common pathways 21359:[DB00027 DB00168] DB00027|Gramicidin D ABCB1 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0055085| transmembrane transport SLC22A6;TRPV1;ABCB1;SLC22A8;SLC22A11 GO:0006810| transport ABCB1;TRPV1 21360:[DB00027 DB07873] DB00027|Gramicidin D ABCB1 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways 21361:[DB00027 DB12307] DB00027|Gramicidin D ABCB1 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 21362:[DB00027 DB11587] DB00027|Gramicidin D ABCB1 DB11587|Etafedrine ADRB2 common genes common pathways 21363:[DB00027 DB12436] DB00027|Gramicidin D ABCB1 DB12436|Vofopitant TACR1 common genes common pathways 21364:[DB00027 DB04105] DB00027|Gramicidin D ABCB1 DB04105|N-Heptylformamide ADH1B common genes common pathways 21365:[DB00027 DB05407] DB00027|Gramicidin D ABCB1 DB05407|TBC-3711 EDN1 common genes common pathways GO:0042493| response to drug EDN1;ABCB1 21366:[DB00027 DB12555] DB00027|Gramicidin D ABCB1 DB12555|Nelotanserin HTR2A common genes common pathways GO:0042493| response to drug HTR2A;ABCB1 21367:[DB00027 DB06469] DB00027|Gramicidin D ABCB1 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways 21368:[DB00027 DB06737] DB00027|Gramicidin D ABCB1 DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways 21369:[DB00027 DB08655] DB00027|Gramicidin D ABCB1 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways 21370:[DB00027 DB02360] DB00027|Gramicidin D ABCB1 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways 21371:[DB00027 DB07053] DB00027|Gramicidin D ABCB1 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 21372:[DB00027 DB14583] DB00027|Gramicidin D ABCB1 DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0006810| transport ABCB1;AR 21373:[DB00027 DB08867] DB00027|Gramicidin D ABCB1 DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 GO:0006810| transport AR;ABCB1 21374:[DB00027 DB01251] DB00027|Gramicidin D ABCB1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0055085| transmembrane transport ABCC8;ABCB1 GO:0042493| response to drug ABCB1;ABCC8 21375:[DB00027 DB04942] DB00027|Gramicidin D ABCB1 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways 21376:[DB00027 DB09235] DB00027|Gramicidin D ABCB1 DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0006810| transport ABCB1;CACNA1I GO:0055085| transmembrane transport CACNA1I;ABCB1;CACNA1C 21377:[DB00027 DB04725] DB00027|Gramicidin D ABCB1 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 21378:[DB00027 DB00153] DB00027|Gramicidin D ABCB1 DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways 21379:[DB00027 DB00735] DB00027|Gramicidin D ABCB1 DB00735|Naftifine SQLE common genes common pathways 21380:[DB00027 DB00770] DB00027|Gramicidin D ABCB1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0042493| response to drug ABCC4;ABCB1 GO:0055085| transmembrane transport SLCO2A1;SLC22A6;ABCB1;ABCC5;SLCO2B1;SLCO3A1;ABCC4 GO:0006810| transport ABCB1;ABCC5 21381:[DB00027 DB05956] DB00027|Gramicidin D ABCB1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0006810| transport ABCB1;GRIN2B 21382:[DB00027 DB09256] DB00027|Gramicidin D ABCB1 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0042493| response to drug ABCB1;TYMS;CYP2E1;CYP1A2 21383:[DB00027 DB04967] DB00027|Gramicidin D ABCB1 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0042493| response to drug APEX1;ABCB1;TOP1 21384:[DB00027 DB07422] DB00027|Gramicidin D ABCB1 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways GO:0006810| transport ABCB1;AR 21385:[DB00027 DB09229] DB00027|Gramicidin D ABCB1 DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0055085| transmembrane transport CACNA1S;ABCB1;CACNA1F;CACNA1D;CACNA1C GO:0042493| response to drug ABCB1;ADRA1A 21386:[DB00027 DB06094] DB00027|Gramicidin D ABCB1 DB06094|Apatorsen HSPB1 common genes common pathways 21387:[DB00027 DB04974] DB00027|Gramicidin D ABCB1 DB04974|AP1903 MTOR common genes common pathways 21388:[DB00027 DB00417] DB00027|Gramicidin D ABCB1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1 GO:0006810| transport SLC15A1;ABCB1 21389:[DB00027 DB11691] DB00027|Gramicidin D ABCB1 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0055085| transmembrane transport ABCB5;ABCB1 GO:0006855| drug transmembrane transport ABCB5;ABCB1 GO:0042908| xenobiotic transport ABCB5;ABCB1 21390:[DB00027 DB04471] DB00027|Gramicidin D ABCB1 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways 21391:[DB00027 DB06885] DB00027|Gramicidin D ABCB1 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 21392:[DB00027 DB02263] DB00027|Gramicidin D ABCB1 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways GO:0055085| transmembrane transport SLCO2A1;ABCB1 21393:[DB00027 DB06311] DB00027|Gramicidin D ABCB1 DB06311|Darapladib PLA2G4A common genes common pathways 21394:[DB00027 DB02696] DB00027|Gramicidin D ABCB1 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways 21395:[DB00027 DB08121] DB00027|Gramicidin D ABCB1 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 21396:[DB00027 DB03192] DB00027|Gramicidin D ABCB1 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways 21397:[DB00027 DB14515] DB00027|Gramicidin D ABCB1 DB14515|Magnesium lactate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 21398:[DB00027 DB06985] DB00027|Gramicidin D ABCB1 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways 21399:[DB00027 DB03267] DB00027|Gramicidin D ABCB1 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 21400:[DB00027 DB00738] DB00027|Gramicidin D ABCB1 DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1 21401:[DB00027 DB12569] DB00027|Gramicidin D ABCB1 DB12569|Tonapofylline ADORA1 common genes common pathways 21402:[DB00027 DB09224] DB00027|Gramicidin D ABCB1 DB09224|Melperone DRD2;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;DRD2 21403:[DB00027 DB07234] DB00027|Gramicidin D ABCB1 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways 21404:[DB00027 DB05284] DB00027|Gramicidin D ABCB1 DB05284|CA4P TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB 21405:[DB00027 DB08498] DB00027|Gramicidin D ABCB1 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0042493| response to drug ABCB1;CASP3 21406:[DB00027 DB01969] DB00027|Gramicidin D ABCB1 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 21407:[DB00027 DB00172] DB00027|Gramicidin D ABCB1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;SLC6A14;ABCB1 GO:0006810| transport SLC6A7;ABCB1;SLC6A14 21408:[DB00027 DB01989] DB00027|Gramicidin D ABCB1 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways 21409:[DB00027 DB00269] DB00027|Gramicidin D ABCB1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways 21410:[DB00027 DB02419] DB00027|Gramicidin D ABCB1 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways 21411:[DB00027 DB00497] DB00027|Gramicidin D ABCB1 DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways 21412:[DB00027 DB12128] DB00027|Gramicidin D ABCB1 DB12128|Ulimorelin GHSR common genes common pathways 21413:[DB00027 DB07405] DB00027|Gramicidin D ABCB1 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways 21414:[DB00027 DB00711] DB00027|Gramicidin D ABCB1 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE 21415:[DB00027 DB05420] DB00027|Gramicidin D ABCB1 DB05420|Gallium maltolate RRM1 common genes common pathways 21416:[DB00027 DB08903] DB00027|Gramicidin D ABCB1 DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways 21417:[DB00027 DB08931] DB00027|Gramicidin D ABCB1 DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 21418:[DB00027 DB03187] DB00027|Gramicidin D ABCB1 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 21419:[DB00027 DB01058] DB00027|Gramicidin D ABCB1 DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21420:[DB00027 DB05798] DB00027|Gramicidin D ABCB1 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways 21421:[DB00027 DB07733] DB00027|Gramicidin D ABCB1 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways 21422:[DB00027 DB14012] DB00027|Gramicidin D ABCB1 DB14012|Burosumab FGF23 common genes common pathways 21423:[DB00027 DB07978] DB00027|Gramicidin D ABCB1 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 21424:[DB00027 DB08735] DB00027|Gramicidin D ABCB1 DB08735|R,S-Warfarin alcohol ALB common genes common pathways 21425:[DB00027 DB00332] DB00027|Gramicidin D ABCB1 DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0055085| transmembrane transport SLC22A4;SLC22A5;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 21426:[DB00027 DB05025] DB00027|Gramicidin D ABCB1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0042493| response to drug ABCB1;SOD1 21427:[DB00027 DB06824] DB00027|Gramicidin D ABCB1 DB06824|Triethylenetetramine GPC1 common genes common pathways 21428:[DB00027 DB06245] DB00027|Gramicidin D ABCB1 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways GO:0042493| response to drug ABCB1;CALR 21429:[DB00027 DB06780] DB00027|Gramicidin D ABCB1 DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways 21430:[DB00027 DB05424] DB00027|Gramicidin D ABCB1 DB05424|Canertinib EGFR common genes common pathways 21431:[DB00027 DB05219] DB00027|Gramicidin D ABCB1 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes common pathways 21432:[DB00027 DB00890] DB00027|Gramicidin D ABCB1 DB00890|Dienestrol ESR1;SHBG common genes common pathways 21433:[DB00027 DB05469] DB00027|Gramicidin D ABCB1 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 21434:[DB00027 DB00991] DB00027|Gramicidin D ABCB1 DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 21435:[DB00027 DB02750] DB00027|Gramicidin D ABCB1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways GO:0006810| transport SLC7A8;ABCB1;SLC7A5 21436:[DB00027 DB11638] DB00027|Gramicidin D ABCB1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4A;TUBA1A;TUBB GO:0042493| response to drug SRP14;HNRNPD;LGALS1;LDHA;ABCB1 21437:[DB00027 DB01161] DB00027|Gramicidin D ABCB1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCB1;SLC6A3 GO:0042493| response to drug ABCB1;SLC6A3;BCHE 21438:[DB00027 DB06216] DB00027|Gramicidin D ABCB1 DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2C;HTR2B;DRD2;ADRA1A;ABCB1;HTR1B;DRD3;DRD1;HTR2A;CYP1A2 21439:[DB00027 DB07374] DB00027|Gramicidin D ABCB1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways 21440:[DB00027 DB04882] DB00027|Gramicidin D ABCB1 DB04882|Edotecarin TOP1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 21441:[DB00027 DB14637] DB00027|Gramicidin D ABCB1 DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways 21442:[DB00027 DB06451] DB00027|Gramicidin D ABCB1 DB06451|Aprinocarsen PRKCA common genes common pathways 21443:[DB00027 DB00228] DB00027|Gramicidin D ABCB1 DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0045332| phospholipid translocation KCNN4;ABCB1 GO:0055085| transmembrane transport ABCB1;KCNA1 GO:0006810| transport GABRB1;GABRG2;GABRA4;GABRA6;GABRA1;GABRB3;GABRA3;GABRA5;GABRD;GABRB2;ABCB1 GO:0042493| response to drug GABRG3;CYP2E1;ABCB1 21444:[DB00027 DB07207] DB00027|Gramicidin D ABCB1 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways 21445:[DB00027 DB00663] DB00027|Gramicidin D ABCB1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways 21446:[DB00027 DB00801] DB00027|Gramicidin D ABCB1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport ABCB1;GABRB2;GABRD;GABRR2;GABRA3;GABRA5;GABRB3;GABRA6;GABRR1;GABRA4;GABRA1;GABRG2;GABRB1 GO:0042493| response to drug ABCB1;GABRG3 21447:[DB00027 DB01282] DB00027|Gramicidin D ABCB1 DB01282|Carbetocin OXTR common genes common pathways GO:0042493| response to drug OXTR;ABCB1 21448:[DB00027 DB01143] DB00027|Gramicidin D ABCB1 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways 21449:[DB00027 DB02715] DB00027|Gramicidin D ABCB1 DB02715|Compound 18 ESR1 common genes common pathways 21450:[DB00027 DB00226] DB00027|Gramicidin D ABCB1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug ABCB1;SLC6A2 21451:[DB00027 DB01373] DB00027|Gramicidin D ABCB1 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0055085| transmembrane transport CALM1;CACNA1C;ABCB1 GO:0042493| response to drug ABCB1;AOC1 21452:[DB00027 DB01321] DB00027|Gramicidin D ABCB1 DB01321|Josamycin rplD;CYP3A4 common genes common pathways 21453:[DB00027 DB00631] DB00027|Gramicidin D ABCB1 DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 21454:[DB00027 DB08361] DB00027|Gramicidin D ABCB1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways 21455:[DB00027 DB11136] DB00027|Gramicidin D ABCB1 DB11136|Chromium CYB5A;TF common genes common pathways 21456:[DB00027 DB07159] DB00027|Gramicidin D ABCB1 DB07159|Tamatinib SYK common genes common pathways 21457:[DB00027 DB09209] DB00027|Gramicidin D ABCB1 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways 21458:[DB00027 DB00114] DB00027|Gramicidin D ABCB1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0042493| response to drug GAD1;ABAT;SRR;ABCB1;GAD2 21459:[DB00027 DB02931] DB00027|Gramicidin D ABCB1 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways 21460:[DB00027 DB05513] DB00027|Gramicidin D ABCB1 DB05513|Atiprimod IL6;TNF common genes common pathways 21461:[DB00027 DB11091] DB00027|Gramicidin D ABCB1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0042493| response to drug ABCB1;CAT 21462:[DB00027 DB13153] DB00027|Gramicidin D ABCB1 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1B1 21463:[DB00027 DB01435] DB00027|Gramicidin D ABCB1 DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;CYP2E1 GO:0055085| transmembrane transport SLC22A6;ABCB1 21464:[DB00027 DB11640] DB00027|Gramicidin D ABCB1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0055085| transmembrane transport KCNA1;ABCB1 21465:[DB00027 DB00898] DB00027|Gramicidin D ABCB1 DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;GABRG3;CYP2E1;CYP1A2 GO:0006810| transport CHRNB3;GABRB3;CACNG1;GRIA3;CACNG2;GABRB1;GABRA4;CHRNA6;GABRA6;GABRA1;ABCB1;CACNB1;GRIA4;GABRA3;GABRA5;GABRD;GABRB2 GO:0055085| transmembrane transport CACNA1S;ABCB1;CACNA1C;CACNA1D 21466:[DB00027 DB00197] DB00027|Gramicidin D ABCB1 DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0006810| transport ABCB11;ABCB1 GO:0055085| transmembrane transport ABCB11;SLCO1B1;ABCB1 GO:0042493| response to drug CYP1A1;PPARG;UGT1A1;ABCB1 21467:[DB00027 DB01186] DB00027|Gramicidin D ABCB1 DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2A;DRD1;DRD3;HTR2C;HTR2B;DRD2;ADRA1A;HTR1B;ABCB1 21468:[DB00027 DB03193] DB00027|Gramicidin D ABCB1 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes common pathways GO:0042493| response to drug ABCB1;FABP3 21469:[DB00027 DB00795] DB00027|Gramicidin D ABCB1 DB00795|Sulfasalazine ALOX5;PTGS2;PTGS1;PPARG;CHUK;IKBKB;SLC7A11;ACAT1;TBXAS1;PLA2G1B;ABCG2;ABCC2;SLC46A1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCB1 GO:0042493| response to drug PTGS2;CHUK;PPARG;ABCG2;ABCC2;ABCB1 GO:0006810| transport ABCB1;ABCC2;ABCG2 GO:0055085| transmembrane transport SLCO2B1;ABCC2;ABCG2;ABCB1;SLCO1B1;SLCO1B3;SLC46A1 21470:[DB00027 DB11569] DB00027|Gramicidin D ABCB1 DB11569|Ixekizumab IL17A common genes common pathways 21471:[DB00027 DB01032] DB00027|Gramicidin D ABCB1 DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0055085| transmembrane transport SLC22A2;ABCC5;ABCC2;PANX1;SLC10A1;ABCC11;ABCB1;ABCC1;SLC22A1;ABCC3;SLCO1C1;ABCC6;SLC22A6;SLC22A10;SLC22A11;SLC16A1;SLC22A12;SLC22A7;ABCC4;SLC22A8;SLC22A5;SLC2A9;SLCO1A2;SLC16A7 GO:0006810| transport ABCC2;ABCC5;ABCB1;SLC10A1;ABCC6;ABCC3;ABCC1 GO:0042493| response to drug ABCC2;ABCB1;UGT1A1;ABCC1;ABCC6;SLC22A12;ABCC4 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;ABCC2;ABCC1;ABCC3;SLC22A1;SLC22A5 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC3;ABCC1 21472:[DB00027 DB06345] DB00027|Gramicidin D ABCB1 DB06345|AR-9281 EPHX2 common genes common pathways 21473:[DB00027 DB01130] DB00027|Gramicidin D ABCB1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways 21474:[DB00027 DB06151] DB00027|Gramicidin D ABCB1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0006810| transport ABCB1;GRIN2A;GRIN2B GO:0055085| transmembrane transport ABCB1;SLC22A6;SLCO1B1 GO:0042493| response to drug ABCB1;CHUK;GRIN2A 21475:[DB00027 DB03704] DB00027|Gramicidin D ABCB1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways 21476:[DB00027 DB06634] DB00027|Gramicidin D ABCB1 DB06634|Casopitant CYP3A4;TACR1 common genes common pathways 21477:[DB00027 DB05024] DB00027|Gramicidin D ABCB1 DB05024|CTA018 CYP24A1;VDR common genes common pathways 21478:[DB00027 DB09488] DB00027|Gramicidin D ABCB1 DB09488|Acrivastine HRH1 common genes common pathways 21479:[DB00027 DB00628] DB00027|Gramicidin D ABCB1 DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0006810| transport GABRB3;GABRA1;GABRA4;GABRA6;GABRB1;GABRG2;ABCB1;GABRD;GABRB2;GABRA5;GABRA3 GO:0042493| response to drug GABRG3;TSPO;ABCB1 21480:[DB00027 DB09089] DB00027|Gramicidin D ABCB1 DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0045332| phospholipid translocation KCNN4;ABCB1 GO:0006810| transport CACNB3;CACNB1;ABCB1;CACNA1I;CACNB4 GO:0055085| transmembrane transport CACNA1G;CACNA1S;CACNA1I;ABCB1;CACNA1F;CACNA1H;KCNMA1;CACNA1D;CACNA1C 21481:[DB00027 DB08869] DB00027|Gramicidin D ABCB1 DB08869|Tesamorelin GHRHR common genes common pathways 21482:[DB00027 DB09570] DB00027|Gramicidin D ABCB1 DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21483:[DB00027 DB08815] DB00027|Gramicidin D ABCB1 DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0042493| response to drug DRD2;ABCB1;HTR2A 21484:[DB00027 DB00400] DB00027|Gramicidin D ABCB1 DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 21485:[DB00027 DB07465] DB00027|Gramicidin D ABCB1 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways 21486:[DB00027 DB03507] DB00027|Gramicidin D ABCB1 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways 21487:[DB00027 DB05869] DB00027|Gramicidin D ABCB1 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways 21488:[DB00027 DB01629] DB00027|Gramicidin D ABCB1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0042493| response to drug SOD1;ABCB1 21489:[DB00027 DB12478] DB00027|Gramicidin D ABCB1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD2;ABCB1;DRD3 21490:[DB00027 DB00208] DB00027|Gramicidin D ABCB1 DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;CYP1A1;ABCB1 21491:[DB00027 DB01021] DB00027|Gramicidin D ABCB1 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0042493| response to drug ABCB1;ATP1A1 GO:0055085| transmembrane transport ABCB1;SLC12A3 GO:0006810| transport SLC12A3;ABCB1 21492:[DB00027 DB00824] DB00027|Gramicidin D ABCB1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0042493| response to drug ADORA2A;ABCB1 21493:[DB00027 DB11834] DB00027|Gramicidin D ABCB1 DB11834|Guselkumab IL23A common genes common pathways 21494:[DB00027 DB02546] DB00027|Gramicidin D ABCB1 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0042493| response to drug HDAC2;HDAC1;ABCB1 21495:[DB00027 DB00848] DB00027|Gramicidin D ABCB1 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways 21496:[DB00027 DB04947] DB00027|Gramicidin D ABCB1 DB04947|Altropane SLC6A3 common genes common pathways GO:0055085| transmembrane transport SLC6A3;ABCB1 GO:0042493| response to drug SLC6A3;ABCB1 21497:[DB00027 DB01860] DB00027|Gramicidin D ABCB1 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 21498:[DB00027 DB02917] DB00027|Gramicidin D ABCB1 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways 21499:[DB00027 DB11124] DB00027|Gramicidin D ABCB1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 21500:[DB00027 DB02226] DB00027|Gramicidin D ABCB1 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 21501:[DB00027 DB09018] DB00027|Gramicidin D ABCB1 DB09018|Bromopride DRD2 common genes common pathways GO:0042493| response to drug ABCB1;DRD2 21502:[DB00027 DB01096] DB00027|Gramicidin D ABCB1 DB01096|Oxamniquine CYP2D6 common genes common pathways 21503:[DB00027 DB06587] DB00027|Gramicidin D ABCB1 DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways 21504:[DB00027 DB05990] DB00027|Gramicidin D ABCB1 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 21505:[DB00027 DB05797] DB00027|Gramicidin D ABCB1 DB05797|TNX-901 FCER1A common genes common pathways 21506:[DB00027 DB07402] DB00027|Gramicidin D ABCB1 DB07402|Azapropazone ALB common genes common pathways 21507:[DB00027 DB04700] DB00027|Gramicidin D ABCB1 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways 21508:[DB00027 DB04593] DB00027|Gramicidin D ABCB1 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways 21509:[DB00027 DB02209] DB00027|Gramicidin D ABCB1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways 21510:[DB00027 DB05088] DB00027|Gramicidin D ABCB1 DB05088|Tiomolibdate ion APP common genes common pathways 21511:[DB00027 DB09241] DB00027|Gramicidin D ABCB1 DB09241|Methylene blue GUCY1A2;NOS1 common genes common pathways 21512:[DB00027 DB08590] DB00027|Gramicidin D ABCB1 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways 21513:[DB00027 DB05749] DB00027|Gramicidin D ABCB1 DB05749|MPI-674 CYP19A1 common genes common pathways 21514:[DB00027 DB09363] DB00027|Gramicidin D ABCB1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC18A2;SLC6A2;ABCB1 GO:0042493| response to drug SLC6A2;MAOB;ABCB1 21515:[DB00027 DB00912] DB00027|Gramicidin D ABCB1 DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB11;SLCO1B1;ABCC8;ABCB1 GO:0006810| transport ABCB11;ABCB1 GO:0042493| response to drug ABCC8;ABCB1;PPARG 21516:[DB00027 DB04888] DB00027|Gramicidin D ABCB1 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0042493| response to drug ABCB1;DRD2 21517:[DB00027 DB14010] DB00027|Gramicidin D ABCB1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;HTR2A 21518:[DB00027 DB01256] DB00027|Gramicidin D ABCB1 DB01256|Retapamulin rplC;CYP3A4 common genes common pathways 21519:[DB00027 DB14509] DB00027|Gramicidin D ABCB1 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006810| transport GRIA3;ABCB1 21520:[DB00027 DB04345] DB00027|Gramicidin D ABCB1 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways 21521:[DB00027 DB04836] DB00027|Gramicidin D ABCB1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 GO:0006810| transport ABCB1;SLC6A2 21522:[DB00027 DB13192] DB00027|Gramicidin D ABCB1 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways 21523:[DB00027 DB00211] DB00027|Gramicidin D ABCB1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0006810| transport ABCB1;SLC15A1 GO:0055085| transmembrane transport ABCB1;SLC15A1 GO:0042493| response to drug ABCB1;ADRA1A 21524:[DB00027 DB01564] DB00027|Gramicidin D ABCB1 DB01564|Calusterone AR common genes common pathways GO:0006810| transport AR;ABCB1 21525:[DB00027 DB08895] DB00027|Gramicidin D ABCB1 DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways 21526:[DB00027 DB01324] DB00027|Gramicidin D ABCB1 DB01324|Polythiazide SLC12A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC12A3 GO:0006810| transport SLC12A3;ABCB1 21527:[DB00027 DB03058] DB00027|Gramicidin D ABCB1 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways 21528:[DB00027 DB05005] DB00027|Gramicidin D ABCB1 DB05005|CCX282 CCR9 common genes common pathways 21529:[DB00027 DB08008] DB00027|Gramicidin D ABCB1 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 21530:[DB00027 DB14539] DB00027|Gramicidin D ABCB1 DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1;ABCG2;SLCO1A2;SLC22A8 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0042493| response to drug ABCB1;ABCG2;ANXA1;HSD11B2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 21531:[DB00027 DB03686] DB00027|Gramicidin D ABCB1 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways 21532:[DB00027 DB03309] DB00027|Gramicidin D ABCB1 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways 21533:[DB00027 DB04003] DB00027|Gramicidin D ABCB1 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways GO:0042493| response to drug ABCB1;LCK 21534:[DB00027 DB04767] DB00027|Gramicidin D ABCB1 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways 21535:[DB00027 DB05885] DB00027|Gramicidin D ABCB1 DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CACNA1B;ABCB1;SV2A GO:0006810| transport CACNA1B;ABCB1 21536:[DB00027 DB11127] DB00027|Gramicidin D ABCB1 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways 21537:[DB00027 DB09204] DB00027|Gramicidin D ABCB1 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 21538:[DB00027 DB08826] DB00027|Gramicidin D ABCB1 DB08826|Deferiprone UGT1A6 common genes common pathways 21539:[DB00027 DB08588] DB00027|Gramicidin D ABCB1 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways 21540:[DB00027 DB01205] DB00027|Gramicidin D ABCB1 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug ABCB1;GABRG3 GO:0006810| transport GABRB3;GABRB1;GABRG2;GABRA6;GABRA4;GABRA1;ABCB1;GABRA5;GABRA3;GABRB2;GABRD 21541:[DB00027 DB09185] DB00027|Gramicidin D ABCB1 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0042493| response to drug SLC6A2;ABCB1;CYP1A2 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport ABCB1;SLC6A2 21542:[DB00027 DB08504] DB00027|Gramicidin D ABCB1 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways 21543:[DB00027 DB03696] DB00027|Gramicidin D ABCB1 DB03696|Lanosterol LSS common genes common pathways 21544:[DB00027 DB06013] DB00027|Gramicidin D ABCB1 DB06013|Aldoxorubicin TOP2A common genes common pathways 21545:[DB00027 DB05968] DB00027|Gramicidin D ABCB1 DB05968|PR-104 TNF common genes common pathways 21546:[DB00027 DB14004] DB00027|Gramicidin D ABCB1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways 21547:[DB00027 DB00708] DB00027|Gramicidin D ABCB1 DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways 21548:[DB00027 DB09148] DB00027|Gramicidin D ABCB1 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways 21549:[DB00027 DB03167] DB00027|Gramicidin D ABCB1 DB03167|Pentabromophenol TTR common genes common pathways GO:0006810| transport ABCB1;TTR 21550:[DB00027 DB05786] DB00027|Gramicidin D ABCB1 DB05786|Irofulven FUBP1 common genes common pathways 21551:[DB00027 DB00407] DB00027|Gramicidin D ABCB1 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 21552:[DB00027 DB00822] DB00027|Gramicidin D ABCB1 DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0006810| transport ABCB1;ABCB11 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0042493| response to drug CYP2E1;ABCB1 21553:[DB00027 DB06907] DB00027|Gramicidin D ABCB1 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport TTR;ABCB1 21554:[DB00027 DB05014] DB00027|Gramicidin D ABCB1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0042493| response to drug RET;ABCB1 21555:[DB00027 DB11590] DB00027|Gramicidin D ABCB1 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ITPR1 GO:0006810| transport ABCB1;FXYD2 21556:[DB00027 DB06481] DB00027|Gramicidin D ABCB1 DB06481|Manitimus DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 21557:[DB00027 DB09378] DB00027|Gramicidin D ABCB1 DB09378|Fluprednisolone CYP3A4 common genes common pathways 21558:[DB00027 DB00250] DB00027|Gramicidin D ABCB1 DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 21559:[DB00027 DB07015] DB00027|Gramicidin D ABCB1 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways 21560:[DB00027 DB00980] DB00027|Gramicidin D ABCB1 DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21561:[DB00027 DB00167] DB00027|Gramicidin D ABCB1 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 21562:[DB00027 DB02459] DB00027|Gramicidin D ABCB1 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways 21563:[DB00027 DB00241] DB00027|Gramicidin D ABCB1 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006810| transport ABCB1;GABRB2;GABRD;GABRA3;GABRA5;GABRB3;GABRA1;GABRA4;GABRA6;GRIK2;GABRB1;GABRG2 GO:0042493| response to drug GABRG3;ABCB1 21564:[DB00027 DB02638] DB00027|Gramicidin D ABCB1 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways 21565:[DB00027 DB05159] DB00027|Gramicidin D ABCB1 DB05159|CCX915 CCR2 common genes common pathways 21566:[DB00027 DB06069] DB00027|Gramicidin D ABCB1 DB06069|XMT-1001 TOP1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 21567:[DB00027 DB02074] DB00027|Gramicidin D ABCB1 DB02074|Butenoic Acid FABP1 common genes common pathways 21568:[DB00027 DB14033] DB00027|Gramicidin D ABCB1 DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways 21569:[DB00027 DB05712] DB00027|Gramicidin D ABCB1 DB05712|AZD-9684 CPB2 common genes common pathways GO:0042493| response to drug CPB2;ABCB1 21570:[DB00027 DB00467] DB00027|Gramicidin D ABCB1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 21571:[DB00027 DB08837] DB00027|Gramicidin D ABCB1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0055085| transmembrane transport KCNA1;ABCB1;SLC22A2;SLC22A1;SLC47A1;SLC22A4;SLC22A3;SLC22A5;SLC22A8 GO:0006855| drug transmembrane transport SLC22A3;SLC22A5;SLC47A1;SLC22A1;ABCB1;SLC22A2 21572:[DB00027 DB00187] DB00027|Gramicidin D ABCB1 DB00187|Esmolol ADRB1;CYP2D6 common genes common pathways 21573:[DB00027 DB03336] DB00027|Gramicidin D ABCB1 DB03336|BIA COMT common genes common pathways GO:0042493| response to drug ABCB1;COMT 21574:[DB00027 DB12693] DB00027|Gramicidin D ABCB1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2A;ABCB1 21575:[DB00027 DB06817] DB00027|Gramicidin D ABCB1 DB06817|Raltegravir pol;UGT1A1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 21576:[DB00027 DB09124] DB00027|Gramicidin D ABCB1 DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways 21577:[DB00027 DB06892] DB00027|Gramicidin D ABCB1 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways 21578:[DB00027 DB05553] DB00027|Gramicidin D ABCB1 DB05553|Regrelor P2RY12 common genes common pathways 21579:[DB00027 DB00013] DB00027|Gramicidin D ABCB1 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways 21580:[DB00027 DB08672] DB00027|Gramicidin D ABCB1 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways 21581:[DB00027 DB07176] DB00027|Gramicidin D ABCB1 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 21582:[DB00027 DB01222] DB00027|Gramicidin D ABCB1 DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0006810| transport ABCB11;ABCB1 GO:0055085| transmembrane transport ABCB11;ABCB1 21583:[DB00027 DB06446] DB00027|Gramicidin D ABCB1 DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;CACNA1A GO:0042493| response to drug HTR2C;ABCB1;HTR2A 21584:[DB00027 DB09383] DB00027|Gramicidin D ABCB1 DB09383|Meprednisone CYP3A4;ALB common genes common pathways 21585:[DB00027 DB01403] DB00027|Gramicidin D ABCB1 DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0042493| response to drug DRD3;ABCB1;DRD2;ADRA1A;HTR2C;CYP2E1;HTR2A;DRD1 21586:[DB00027 DB14009] DB00027|Gramicidin D ABCB1 DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0042493| response to drug PPARG;CYP1A1;TRPA1;ABCC1;SMPD1;ABCG2;ABCB1;SOD1;HTR2A;PTGS2;CYP1A2;CAT GO:0055085| transmembrane transport ABCG2;TRPM8;TRPV1;VDAC1;ABCB1;TRPV4;CACNA1I;TRPA1;CACNA1G;ABCC1;TRPV2;CACNA1H;TRPV3 GO:0006810| transport TRPV2;ABCB1;CACNA1I;TRPV1;ABCG2;ABCC1 21587:[DB00027 DB00137] DB00027|Gramicidin D ABCB1 DB00137|Lutein ALB common genes common pathways 21588:[DB00027 DB08954] DB00027|Gramicidin D ABCB1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0006810| transport ABCB1;GRIN2B 21589:[DB00027 DB01345] DB00027|Gramicidin D ABCB1 DB01345|Potassium cation ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1 21590:[DB00027 DB11338] DB00027|Gramicidin D ABCB1 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0042493| response to drug ABCB1;COL1A1 21591:[DB00027 DB00505] DB00027|Gramicidin D ABCB1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways 21592:[DB00027 DB09499] DB00027|Gramicidin D ABCB1 DB09499|Thiosulfuric acid TST common genes common pathways 21593:[DB00027 DB00166] DB00027|Gramicidin D ABCB1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0042493| response to drug ABCB1;POR GO:0006810| transport SLC5A6;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC5A6 21594:[DB00027 DB04149] DB00027|Gramicidin D ABCB1 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways 21595:[DB00027 DB11635] DB00027|Gramicidin D ABCB1 DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCA1;ABCG8;ABCG5;ABCB1 GO:0006810| transport TTPA;ABCB1 GO:0042493| response to drug ABCA1;ABCB1;ABCG5;ABCG8;NPC1L1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG5 GO:0045332| phospholipid translocation ABCA1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 21596:[DB00027 DB08370] DB00027|Gramicidin D ABCB1 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways 21597:[DB00027 DB00837] DB00027|Gramicidin D ABCB1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0006810| transport GABRA1;ABCB1 21598:[DB00027 DB06785] DB00027|Gramicidin D ABCB1 DB06785|Ganirelix GNRHR common genes common pathways 21599:[DB00027 DB11235] DB00027|Gramicidin D ABCB1 DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 21600:[DB00027 DB13620] DB00027|Gramicidin D ABCB1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1 GO:0006810| transport ATP4A;ABCB1;FXYD2;SLC12A1 GO:0055085| transmembrane transport SLC12A1;ABCB1 21601:[DB00027 DB01191] DB00027|Gramicidin D ABCB1 DB01191|Dexfenfluramine SLC6A4;HTR2C;CYP2D6;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug SLC6A4;CYP2E1;CYP1A2;HTR2C;ABCB1 GO:0055085| transmembrane transport SLC6A4;ABCB1 21602:[DB00027 DB05137] DB00027|Gramicidin D ABCB1 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways 21603:[DB00027 DB04459] DB00027|Gramicidin D ABCB1 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways 21604:[DB00027 DB07101] DB00027|Gramicidin D ABCB1 DB07101|PD-0325901 MAP2K1 common genes common pathways 21605:[DB00027 DB04754] DB00027|Gramicidin D ABCB1 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1 21606:[DB00027 DB03695] DB00027|Gramicidin D ABCB1 DB03695|Piritrexim DHFR common genes common pathways 21607:[DB00027 DB01173] DB00027|Gramicidin D ABCB1 DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SCN10A;SLC6A2 GO:0042493| response to drug CYP2E1;CYP1A2;SLC6A2;ABCB1 21608:[DB00027 DB00915] DB00027|Gramicidin D ABCB1 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC22A1 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0042493| response to drug MAOB;ABCB1;DRD2 21609:[DB00027 DB02877] DB00027|Gramicidin D ABCB1 DB02877|Arotinoid acid RARB common genes common pathways 21610:[DB00027 DB08454] DB00027|Gramicidin D ABCB1 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways 21611:[DB00027 DB06706] DB00027|Gramicidin D ABCB1 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC18A2 GO:0042493| response to drug ADRA1A;ABCB1 21612:[DB00027 DB00238] DB00027|Gramicidin D ABCB1 DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 GO:0055085| transmembrane transport SLC22A1;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 21613:[DB00027 DB00214] DB00027|Gramicidin D ABCB1 DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0055085| transmembrane transport SLC12A1;ABCB1 GO:0006810| transport ABCB1;SLC12A1 21614:[DB00027 DB11792] DB00027|Gramicidin D ABCB1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 21615:[DB00027 DB03856] DB00027|Gramicidin D ABCB1 DB03856|L-Eflornithine ODC1 common genes common pathways 21616:[DB00027 DB01120] DB00027|Gramicidin D ABCB1 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0042493| response to drug ABCB1;ABCC8 GO:0055085| transmembrane transport ABCB1;ABCC8 21617:[DB00027 DB07339] DB00027|Gramicidin D ABCB1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways 21618:[DB00027 DB04956] DB00027|Gramicidin D ABCB1 DB04956|Afelimomab TNF common genes common pathways 21619:[DB00027 DB06471] DB00027|Gramicidin D ABCB1 DB06471|Naxifylline ADORA1 common genes common pathways 21620:[DB00027 DB00423] DB00027|Gramicidin D ABCB1 DB00423|Methocarbamol CA1 common genes common pathways 21621:[DB00027 DB06726] DB00027|Gramicidin D ABCB1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways 21622:[DB00027 DB01933] DB00027|Gramicidin D ABCB1 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways 21623:[DB00027 DB03606] DB00027|Gramicidin D ABCB1 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways 21624:[DB00027 DB11477] DB00027|Gramicidin D ABCB1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways 21625:[DB00027 DB00244] DB00027|Gramicidin D ABCB1 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0042493| response to drug CHUK;PTGS2;ABCB1;PPARG 21626:[DB00027 DB03977] DB00027|Gramicidin D ABCB1 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CALM1 21627:[DB00027 DB11274] DB00027|Gramicidin D ABCB1 DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0042493| response to drug DRD2;ABCB1;DRD3;DRD1 21628:[DB00027 DB00070] DB00027|Gramicidin D ABCB1 DB00070|Hyaluronidase TGFB1;ALB common genes common pathways GO:0042493| response to drug ABCB1;TGFB1 21629:[DB00027 DB00274] DB00027|Gramicidin D ABCB1 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport SLC15A2;ABCB1;SLC15A1 21630:[DB00027 DB01352] DB00027|Gramicidin D ABCB1 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport GRIK2;GABRA6;GABRA4;GABRA1;GABRA5;GABRA3;ABCB1 21631:[DB00027 DB06468] DB00027|Gramicidin D ABCB1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC9A1 21632:[DB00027 DB07638] DB00027|Gramicidin D ABCB1 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways 21633:[DB00027 DB06833] DB00027|Gramicidin D ABCB1 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways 21634:[DB00027 DB13932] DB00027|Gramicidin D ABCB1 DB13932|Voretigene Neparvovec RPE65 common genes common pathways 21635:[DB00027 DB06358] DB00027|Gramicidin D ABCB1 DB06358|Iclaprim DHFR common genes common pathways 21636:[DB00027 DB14185] DB00027|Gramicidin D ABCB1 DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0042493| response to drug HTR2A;DRD1;DRD3;DRD2;ADRA1A;ABCB1;HTR1B;HTR2C 21637:[DB00027 DB02306] DB00027|Gramicidin D ABCB1 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 21638:[DB00027 DB09276] DB00027|Gramicidin D ABCB1 DB09276|Sodium aurothiomalate UGT1A1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 21639:[DB00027 DB00689] DB00027|Gramicidin D ABCB1 DB00689|Cephaloglycin SLC22A5 common genes common pathways GO:0055085| transmembrane transport SLC22A5;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 21640:[DB00027 DB08089] DB00027|Gramicidin D ABCB1 DB08089|LGD-2226 AR common genes common pathways GO:0006810| transport AR;ABCB1 21641:[DB00027 DB01044] DB00027|Gramicidin D ABCB1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21642:[DB00027 DB04012] DB00027|Gramicidin D ABCB1 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways 21643:[DB00027 DB02557] DB00027|Gramicidin D ABCB1 DB02557|Phosphoramidon MME;KEL common genes common pathways 21644:[DB00027 DB04281] DB00027|Gramicidin D ABCB1 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 21645:[DB00027 DB05171] DB00027|Gramicidin D ABCB1 DB05171|E-2012 APH1A;PSENEN common genes common pathways 21646:[DB00027 DB04894] DB00027|Gramicidin D ABCB1 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways 21647:[DB00027 DB00772] DB00027|Gramicidin D ABCB1 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways GO:0042493| response to drug BCHE;ABCB1;CYP1A2 21648:[DB00027 DB07135] DB00027|Gramicidin D ABCB1 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways 21649:[DB00027 DB01206] DB00027|Gramicidin D ABCB1 DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways 21650:[DB00027 DB07525] DB00027|Gramicidin D ABCB1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways 21651:[DB00027 DB06993] DB00027|Gramicidin D ABCB1 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways 21652:[DB00027 DB08953] DB00027|Gramicidin D ABCB1 DB08953|Indalpine CYP3A4 common genes common pathways 21653:[DB00027 DB02919] DB00027|Gramicidin D ABCB1 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways 21654:[DB00027 DB01131] DB00027|Gramicidin D ABCB1 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 21655:[DB00027 DB07141] DB00027|Gramicidin D ABCB1 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 21656:[DB00027 DB05078] DB00027|Gramicidin D ABCB1 DB05078|AER001 IL4R;IL13RA2 common genes common pathways 21657:[DB00027 DB00572] DB00027|Gramicidin D ABCB1 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0006810| transport ABCB11;ABCB1 GO:0055085| transmembrane transport ABCB11;ABCB1 21658:[DB00027 DB05332] DB00027|Gramicidin D ABCB1 DB05332|Romiplostim MPL common genes common pathways 21659:[DB00027 DB05339] DB00027|Gramicidin D ABCB1 DB05339|MN-305 HTR1A common genes common pathways 21660:[DB00027 DB00598] DB00027|Gramicidin D ABCB1 DB00598|Labetalol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP2C19 common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 21661:[DB00027 DB07036] DB00027|Gramicidin D ABCB1 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways 21662:[DB00027 DB00415] DB00027|Gramicidin D ABCB1 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0055085| transmembrane transport SLC22A5;SLC15A2;SLC16A1;SLC15A1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 21663:[DB00027 DB00110] DB00027|Gramicidin D ABCB1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 21664:[DB00027 DB00312] DB00027|Gramicidin D ABCB1 DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0042493| response to drug GABRG3;GRIN2A;ABCB1 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport ABCB1;GABRA3;GABRA5;GRIN2C;GABRD;GABRB2;GRIN2A;GABRB3;GABRG2;GABRB1;GABRA1;GRIN2B;GABRA4;GABRA6;GRIK2 21665:[DB00027 DB01094] DB00027|Gramicidin D ABCB1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;CYP1A2 GO:0006810| transport ABCB1;ABCG2 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 21666:[DB00027 DB05139] DB00027|Gramicidin D ABCB1 DB05139|CR002 PDGFD common genes common pathways 21667:[DB00027 DB11275] DB00027|Gramicidin D ABCB1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0042493| response to drug DRD1;DRD2;ABCB1;DRD3 21668:[DB00027 DB00650] DB00027|Gramicidin D ABCB1 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 21669:[DB00027 DB08980] DB00027|Gramicidin D ABCB1 DB08980|Fendiline CYP3A4 common genes common pathways 21670:[DB00027 DB01247] DB00027|Gramicidin D ABCB1 DB01247|Isocarboxazid MAOA;MAOB common genes common pathways GO:0042493| response to drug MAOB;ABCB1 21671:[DB00027 DB05001] DB00027|Gramicidin D ABCB1 DB05001|PSN9301 DPP4 common genes common pathways 21672:[DB00027 DB00111] DB00027|Gramicidin D ABCB1 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 21673:[DB00027 DB13933] DB00027|Gramicidin D ABCB1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways 21674:[DB00027 DB04796] DB00027|Gramicidin D ABCB1 DB04796|Inecalcitol VDR common genes common pathways 21675:[DB00027 DB13948] DB00027|Gramicidin D ABCB1 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0042493| response to drug ABCB1;HTR2A 21676:[DB00027 DB08574] DB00027|Gramicidin D ABCB1 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 21677:[DB00027 DB01466] DB00027|Gramicidin D ABCB1 DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;POR 21678:[DB00027 DB00568] DB00027|Gramicidin D ABCB1 DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;DRD1;CYP1A1;ABCB1;DRD2 GO:0055085| transmembrane transport CACNA1S;CACNA1G;CACNA1F;ABCB1;CACNA1I;CACNA1H;CACNA1C;CACNA1D GO:0006810| transport ABCB1;CACNA1I 21679:[DB00027 DB07768] DB00027|Gramicidin D ABCB1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways 21680:[DB00027 DB05482] DB00027|Gramicidin D ABCB1 DB05482|7-ethyl-10-hydroxycamptothecin TOP1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 21681:[DB00027 DB01053] DB00027|Gramicidin D ABCB1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport SLC22A8;SLC15A2;SLC22A5;SLCO1B1;SLC22A4;SLCO3A1;SLCO4A1;SLC22A11;SLC15A1;SLC22A6;SLCO2B1;ABCB1 21682:[DB00027 DB06830] DB00027|Gramicidin D ABCB1 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 21683:[DB00027 DB03247] DB00027|Gramicidin D ABCB1 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0042493| response to drug DHODH;POR;ABCB1 21684:[DB00027 DB03907] DB00027|Gramicidin D ABCB1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0042493| response to drug ABCB1;COMT 21685:[DB00027 DB01085] DB00027|Gramicidin D ABCB1 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 21686:[DB00027 DB06354] DB00027|Gramicidin D ABCB1 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways GO:0006810| transport ABCB1;GRIK1 GO:0055085| transmembrane transport GRIK1;ABCB1 21687:[DB00027 DB12773] DB00027|Gramicidin D ABCB1 DB12773|Sifalimumab IFNA2 common genes common pathways 21688:[DB00027 DB04521] DB00027|Gramicidin D ABCB1 DB04521|GSHNA GSTA3 common genes common pathways 21689:[DB00027 DB04756] DB00027|Gramicidin D ABCB1 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 21690:[DB00027 DB11731] DB00027|Gramicidin D ABCB1 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB 21691:[DB00027 DB04753] DB00027|Gramicidin D ABCB1 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 21692:[DB00027 DB00883] DB00027|Gramicidin D ABCB1 DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 21693:[DB00027 DB01033] DB00027|Gramicidin D ABCB1 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0055085| transmembrane transport SLC22A8;ABCC4;ABCC5;ABCB1 GO:0006810| transport ABCB1;ABCC5 GO:0042493| response to drug ABCB1;ABCC4;PPAT 21694:[DB00027 DB05883] DB00027|Gramicidin D ABCB1 DB05883|ABX-PTH PTH common genes common pathways GO:0042493| response to drug PTH;ABCB1 21695:[DB00027 DB06372] DB00027|Gramicidin D ABCB1 DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways 21696:[DB00027 DB08841] DB00027|Gramicidin D ABCB1 DB08841|Tyramine SLC22A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A3 GO:0006855| drug transmembrane transport ABCB1;SLC22A3 21697:[DB00027 DB08814] DB00027|Gramicidin D ABCB1 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways 21698:[DB00027 DB07443] DB00027|Gramicidin D ABCB1 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 21699:[DB00027 DB11619] DB00027|Gramicidin D ABCB1 DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0006810| transport AR;ABCB1 21700:[DB00027 DB07032] DB00027|Gramicidin D ABCB1 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways 21701:[DB00027 DB09272] DB00027|Gramicidin D ABCB1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0042493| response to drug ABCC2;ABCB1 GO:0006810| transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2;SLCO1B1;SLC22A8 GO:0006855| drug transmembrane transport ABCB1;ABCC2 21702:[DB00027 DB00024] DB00027|Gramicidin D ABCB1 DB00024|Thyrotropin alfa TSHR common genes common pathways 21703:[DB00027 DB04871] DB00027|Gramicidin D ABCB1 DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A2;CYP1A1;ABCB1;HTR2C 21704:[DB00027 DB05814] DB00027|Gramicidin D ABCB1 DB05814|GPI-1485 FKBP1A;CYP3A4 common genes common pathways 21705:[DB00027 DB09201] DB00027|Gramicidin D ABCB1 DB09201|Ciglitazone PPARG;CYP3A4;CYP2C8 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 21706:[DB00027 DB00294] DB00027|Gramicidin D ABCB1 DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways 21707:[DB00027 DB00657] DB00027|Gramicidin D ABCB1 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways 21708:[DB00027 DB08844] DB00027|Gramicidin D ABCB1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways GO:0055085| transmembrane transport SLC2A9;SLC22A8;ABCB1;SLC22A6 21709:[DB00027 DB09110] DB00027|Gramicidin D ABCB1 DB09110|Coenzyme M GSR common genes common pathways 21710:[DB00027 DB00810] DB00027|Gramicidin D ABCB1 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways 21711:[DB00027 DB08382] DB00027|Gramicidin D ABCB1 DB08382|Gosogliptin DPP4 common genes common pathways 21712:[DB00027 DB01018] DB00027|Gramicidin D ABCB1 DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways 21713:[DB00027 DB09460] DB00027|Gramicidin D ABCB1 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways GO:0042493| response to drug CA9;ABCB1 GO:2001225| regulation of chloride transport ABCB1;CA2 21714:[DB00027 DB01405] DB00027|Gramicidin D ABCB1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21715:[DB00027 DB02613] DB00027|Gramicidin D ABCB1 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0042493| response to drug DHODH;ABCB1 21716:[DB00027 DB13873] DB00027|Gramicidin D ABCB1 DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes common pathways GO:0042493| response to drug PPARG;ABCB1 GO:0042908| xenobiotic transport NR1I2;ABCB1 21717:[DB00027 DB05361] DB00027|Gramicidin D ABCB1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways 21718:[DB00027 DB08875] DB00027|Gramicidin D ABCB1 DB08875|Cabozantinib MET;KDR;RET;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0042493| response to drug RET;ABCB1 21719:[DB00027 DB01409] DB00027|Gramicidin D ABCB1 DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0055085| transmembrane transport SLC22A4;SLC22A5;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 21720:[DB00027 DB00812] DB00027|Gramicidin D ABCB1 DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 GO:0055085| transmembrane transport SLC22A8;SLC22A11;SLC22A6;ABCB1 21721:[DB00027 DB08784] DB00027|Gramicidin D ABCB1 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 21722:[DB00027 DB02285] DB00027|Gramicidin D ABCB1 DB02285|Protoporphyrin FTL common genes common pathways 21723:[DB00027 DB00038] DB00027|Gramicidin D ABCB1 DB00038|Oprelvekin IL11RA common genes common pathways 21724:[DB00027 DB00512] DB00027|Gramicidin D ABCB1 DB00512|Vancomycin ALB;ORM1;ORM2 common genes common pathways 21725:[DB00027 DB00865] DB00027|Gramicidin D ABCB1 DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0042493| response to drug SLC6A3;POR;ABCB1;ADRA1A GO:0055085| transmembrane transport SLC6A3;ABCB1;SLC18A2 21726:[DB00027 DB06231] DB00027|Gramicidin D ABCB1 DB06231|Caldaret SLC8A1 common genes common pathways GO:0042493| response to drug SLC8A1;ABCB1 GO:0055085| transmembrane transport SLC8A1;ABCB1 21727:[DB00027 DB13941] DB00027|Gramicidin D ABCB1 DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 21728:[DB00027 DB00160] DB00027|Gramicidin D ABCB1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0042493| response to drug ABAT;ABCB1 GO:0006810| transport SLC7A8;ABCB1 GO:0055085| transmembrane transport SLC1A4;ABCB1;SLC16A10;SLC36A1 21729:[DB00027 DB00764] DB00027|Gramicidin D ABCB1 DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways 21730:[DB00027 DB00596] DB00027|Gramicidin D ABCB1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways 21731:[DB00027 DB07008] DB00027|Gramicidin D ABCB1 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways 21732:[DB00027 DB00094] DB00027|Gramicidin D ABCB1 DB00094|Urofollitropin FSHR common genes common pathways 21733:[DB00027 DB00189] DB00027|Gramicidin D ABCB1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRD;GABRB2;GABRA5;GABRA3;ABCB1;GABRA1;GABRA4;GABRA6;GABRB1;GABRG2;GABRB3 GO:0042493| response to drug ABCB1;GABRG3 21734:[DB00027 DB09395] DB00027|Gramicidin D ABCB1 DB09395|Sodium acetate ACSS2 common genes common pathways 21735:[DB00027 DB11639] DB00027|Gramicidin D ABCB1 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways 21736:[DB00027 DB11075] DB00027|Gramicidin D ABCB1 DB11075|Hypromellose EPCAM common genes common pathways 21737:[DB00027 DB01366] DB00027|Gramicidin D ABCB1 DB01366|Procaterol ADRB2 common genes common pathways 21738:[DB00027 DB00385] DB00027|Gramicidin D ABCB1 DB00385|Valrubicin TOP2A common genes common pathways 21739:[DB00027 DB14596] DB00027|Gramicidin D ABCB1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways 21740:[DB00027 DB01656] DB00027|Gramicidin D ABCB1 DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways 21741:[DB00027 DB01440] DB00027|Gramicidin D ABCB1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006810| transport ABCB1;GABRB1 GO:0055085| transmembrane transport SLC16A3;ABCB1;SLC16A7;SLC16A1 21742:[DB00027 DB00920] DB00027|Gramicidin D ABCB1 DB00920|Ketotifen HRH1;PGD common genes common pathways 21743:[DB00027 DB13036] DB00027|Gramicidin D ABCB1 DB13036|Ramatroban PTGDR2 common genes common pathways 21744:[DB00027 DB14530] DB00027|Gramicidin D ABCB1 DB14530|Chromous sulfate CYB5A;TF common genes common pathways 21745:[DB00027 DB01144] DB00027|Gramicidin D ABCB1 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways GO:2001225| regulation of chloride transport CA7;ABCB1;CA2 21746:[DB00027 DB12781] DB00027|Gramicidin D ABCB1 DB12781|Balaglitazone CYP3A4;CYP2C8 common genes common pathways 21747:[DB00027 DB00558] DB00027|Gramicidin D ABCB1 DB00558|Zanamivir NEU2 common genes common pathways 21748:[DB00027 DB01623] DB00027|Gramicidin D ABCB1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0042493| response to drug CYP1A2;HTR2A;DRD1;ABCB1;DRD2 GO:0055085| transmembrane transport SLC22A1;ABCB1 21749:[DB00027 DB00033] DB00027|Gramicidin D ABCB1 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 21750:[DB00027 DB00857] DB00027|Gramicidin D ABCB1 DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21751:[DB00027 DB04829] DB00027|Gramicidin D ABCB1 DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2B;ABCB1 21752:[DB00027 DB08168] DB00027|Gramicidin D ABCB1 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways 21753:[DB00027 DB13997] DB00027|Gramicidin D ABCB1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0006855| drug transmembrane transport ABCB1;ABCB5 GO:0055085| transmembrane transport ABCB1;ABCB5 21754:[DB00027 DB01083] DB00027|Gramicidin D ABCB1 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways 21755:[DB00027 DB08044] DB00027|Gramicidin D ABCB1 DB08044|ABT-341 DPP4 common genes common pathways 21756:[DB00027 DB14582] DB00027|Gramicidin D ABCB1 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways 21757:[DB00027 DB00691] DB00027|Gramicidin D ABCB1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 21758:[DB00027 DB02322] DB00027|Gramicidin D ABCB1 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways 21759:[DB00027 DB05442] DB00027|Gramicidin D ABCB1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways 21760:[DB00027 DB09060] DB00027|Gramicidin D ABCB1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0006810| transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLC22A8 GO:0042493| response to drug ABCB1;ABCC2 21761:[DB00027 DB04733] DB00027|Gramicidin D ABCB1 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways 21762:[DB00027 DB00434] DB00027|Gramicidin D ABCB1 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0042493| response to drug ABCB1;HTR2C;HTR2A 21763:[DB00027 DB00949] DB00027|Gramicidin D ABCB1 DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0006810| transport GRIN2A;GRIN2B;ABCB1 GO:0042493| response to drug GRIN2A;CYP2E1;ABCB1 21764:[DB00027 DB04114] DB00027|Gramicidin D ABCB1 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways 21765:[DB00027 DB01599] DB00027|Gramicidin D ABCB1 DB01599|Probucol ABCA1;CES1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCA1 GO:0042493| response to drug ABCA1;ABCB1 GO:0045332| phospholipid translocation ABCA1;ABCB1 21766:[DB00027 DB12465] DB00027|Gramicidin D ABCB1 DB12465|Ketanserin HTR2A common genes common pathways GO:0042493| response to drug ABCB1;HTR2A 21767:[DB00027 DB09258] DB00027|Gramicidin D ABCB1 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways 21768:[DB00027 DB02485] DB00027|Gramicidin D ABCB1 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 21769:[DB00027 DB09046] DB00027|Gramicidin D ABCB1 DB09046|Metreleptin LEPR common genes common pathways 21770:[DB00027 DB05936] DB00027|Gramicidin D ABCB1 DB05936|CVT-6883 ADORA2B common genes common pathways 21771:[DB00027 DB00347] DB00027|Gramicidin D ABCB1 DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055085| transmembrane transport ABCB1;CACNA1G 21772:[DB00027 DB03604] DB00027|Gramicidin D ABCB1 DB03604|Tiratricol THRB common genes common pathways 21773:[DB00027 DB11755] DB00027|Gramicidin D ABCB1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0006810| transport ABCB1;TRPV2 GO:0055085| transmembrane transport TRPA1;ABCB1;TRPM8;TRPV2 GO:0042493| response to drug ABCB1;TRPA1 21774:[DB00027 DB00378] DB00027|Gramicidin D ABCB1 DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways 21775:[DB00027 DB04672] DB00027|Gramicidin D ABCB1 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways 21776:[DB00027 DB01425] DB00027|Gramicidin D ABCB1 DB01425|Alizapride DRD2 common genes common pathways GO:0042493| response to drug ABCB1;DRD2 21777:[DB00027 DB01057] DB00027|Gramicidin D ABCB1 DB01057|Echothiophate BCHE;ALB common genes common pathways GO:0042493| response to drug BCHE;ABCB1 21778:[DB00027 DB01998] DB00027|Gramicidin D ABCB1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways 21779:[DB00027 DB13168] DB00027|Gramicidin D ABCB1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 21780:[DB00027 DB03066] DB00027|Gramicidin D ABCB1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A3;ABCB1;SLC16A7;SLC16A1 21781:[DB00027 DB11892] DB00027|Gramicidin D ABCB1 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21782:[DB00027 DB06756] DB00027|Gramicidin D ABCB1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0055085| transmembrane transport BCL2;ABCB1 GO:0042493| response to drug BCL2;ABCB1;BCHE 21783:[DB00027 DB07389] DB00027|Gramicidin D ABCB1 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways 21784:[DB00027 DB00787] DB00027|Gramicidin D ABCB1 DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways GO:0055085| transmembrane transport SLC47A2;SLC47A1;SLC22A8;ABCB1;SLC10A2;SLC22A6;SLC22A1 GO:0006810| transport ABCB1;SLC10A2 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC47A1;SLC47A2 21785:[DB00027 DB09332] DB00027|Gramicidin D ABCB1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0042493| response to drug ABCB1;POR 21786:[DB00027 DB01170] DB00027|Gramicidin D ABCB1 DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0006810| transport SLC6A2;ABCB1 21787:[DB00027 DB00029] DB00027|Gramicidin D ABCB1 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 21788:[DB00027 DB08051] DB00027|Gramicidin D ABCB1 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways 21789:[DB00027 DB08127] DB00027|Gramicidin D ABCB1 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways 21790:[DB00027 DB03023] DB00027|Gramicidin D ABCB1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0042493| response to drug LCK;ABCB1;LYN;SRC 21791:[DB00027 DB11779] DB00027|Gramicidin D ABCB1 DB11779|Danoprevir CYP3A4 common genes common pathways 21792:[DB00027 DB00550] DB00027|Gramicidin D ABCB1 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1 21793:[DB00027 DB06419] DB00027|Gramicidin D ABCB1 DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways 21794:[DB00027 DB11960] DB00027|Gramicidin D ABCB1 DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways 21795:[DB00027 DB05130] DB00027|Gramicidin D ABCB1 DB05130|INCB3284 CCR2 common genes common pathways 21796:[DB00027 DB09052] DB00027|Gramicidin D ABCB1 DB09052|Blinatumomab CD19;CD3D common genes common pathways 21797:[DB00027 DB08834] DB00027|Gramicidin D ABCB1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCB1 21798:[DB00027 DB01129] DB00027|Gramicidin D ABCB1 DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042493| response to drug CYP1A2;ABCB1;ABCG2;CYP1A1 GO:0006810| transport ABCG2;ATP4A;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 21799:[DB00027 DB03153] DB00027|Gramicidin D ABCB1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 21800:[DB00027 DB12651] DB00027|Gramicidin D ABCB1 DB12651|Bardoxolone CASP8 common genes common pathways 21801:[DB00027 DB00298] DB00027|Gramicidin D ABCB1 DB00298|Dapiprazole ADRA1A;ADRA1D;ADRA1B common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 21802:[DB00027 DB12489] DB00027|Gramicidin D ABCB1 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways 21803:[DB00027 DB00698] DB00027|Gramicidin D ABCB1 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042493| response to drug ABCG2;ABCB1;POR GO:0006810| transport ABCB11;ABCB1;ABCG2 GO:0055085| transmembrane transport ABCB11;ABCG2;ABCB1 21804:[DB00027 DB00145] DB00027|Gramicidin D ABCB1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;SLC36A1;SLC6A9;SLC6A5;ABCB1 GO:0006810| transport GRIN2A;SLC6A9;SLC6A5;ABCB1;GRIN2C GO:0042493| response to drug GRIN2A;ABCB1 21805:[DB00027 DB08892] DB00027|Gramicidin D ABCB1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways GO:0055085| transmembrane transport SLC16A1;ABCB1 21806:[DB00027 DB04410] DB00027|Gramicidin D ABCB1 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways 21807:[DB00027 DB00830] DB00027|Gramicidin D ABCB1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A3;ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3 21808:[DB00027 DB11805] DB00027|Gramicidin D ABCB1 DB11805|Saracatinib CYP3A4 common genes common pathways 21809:[DB00027 DB01708] DB00027|Gramicidin D ABCB1 DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0042493| response to drug ABCB1;GABRG3;GRIN2A GO:0006810| transport GABRA1;GABRA6;GABRA4;GRIN2B;GABRB1;GABRG2;GRIN2A;GABRB3;AR;GABRD;GABRB2;GABRA5;GABRA3;GRIN2C;ABCB1 21810:[DB00027 DB14017] DB00027|Gramicidin D ABCB1 DB14017|H3B-8800 SF3B1 common genes common pathways 21811:[DB00027 DB01108] DB00027|Gramicidin D ABCB1 DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways 21812:[DB00027 DB04861] DB00027|Gramicidin D ABCB1 DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways 21813:[DB00027 DB00052] DB00027|Gramicidin D ABCB1 DB00052|Somatotropin GHR;PRLR common genes common pathways 21814:[DB00027 DB05967] DB00027|Gramicidin D ABCB1 DB05967|ANZ-100 KISS1R common genes common pathways 21815:[DB00027 DB12243] DB00027|Gramicidin D ABCB1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 21816:[DB00027 DB05448] DB00027|Gramicidin D ABCB1 DB05448|PX-12 TXNRD1 common genes common pathways 21817:[DB00027 DB09198] DB00027|Gramicidin D ABCB1 DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0055085| transmembrane transport SLCO3A1;SLCO1B1;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug CYP1A2;PPARG;ABCB1 GO:1901529| ABCB1 21818:[DB00027 DB11830] DB00027|Gramicidin D ABCB1 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways GO:0042493| response to drug HDAC2;ABCB1;HDAC1 21819:[DB00027 DB05532] DB00027|Gramicidin D ABCB1 DB05532|BMS-488043 FFAR4 common genes common pathways 21820:[DB00027 DB05449] DB00027|Gramicidin D ABCB1 DB05449|FM-VP4 ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0006810| transport ABCB1 21821:[DB00027 DB07180] DB00027|Gramicidin D ABCB1 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle NEK2;ABCB1 21822:[DB00027 DB09348] DB00027|Gramicidin D ABCB1 DB09348|Propiolactone ALB common genes common pathways 21823:[DB00027 DB04988] DB00027|Gramicidin D ABCB1 DB04988|IGN311 EGFR;ERBB2 common genes common pathways 21824:[DB00027 DB08058] DB00027|Gramicidin D ABCB1 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 21825:[DB00027 DB09539] DB00027|Gramicidin D ABCB1 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways 21826:[DB00027 DB03953] DB00027|Gramicidin D ABCB1 DB03953|L-Thiocitrulline NOS2 common genes common pathways 21827:[DB00027 DB02933] DB00027|Gramicidin D ABCB1 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 21828:[DB00027 DB02056] DB00027|Gramicidin D ABCB1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO2A1 21829:[DB00027 DB01294] DB00027|Gramicidin D ABCB1 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 21830:[DB00027 DB06643] DB00027|Gramicidin D ABCB1 DB06643|Denosumab TNFSF11 common genes common pathways 21831:[DB00027 DB04723] DB00027|Gramicidin D ABCB1 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways 21832:[DB00027 DB00105] DB00027|Gramicidin D ABCB1 DB00105|Interferon Alfa-2b, Recombinant IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21833:[DB00027 DB04821] DB00027|Gramicidin D ABCB1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0042493| response to drug SLC6A4;SLC6A2;MAOB;SLC6A3;ABCB1 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A2;SLC6A4;SLC18A2 21834:[DB00027 DB02565] DB00027|Gramicidin D ABCB1 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways 21835:[DB00027 DB00193] DB00027|Gramicidin D ABCB1 DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 GO:0006810| transport ABCB1;SLC6A2 GO:0042493| response to drug SLC6A2;UGT1A1;ABCB1;HTR2C;SLC6A4 21836:[DB00027 DB01022] DB00027|Gramicidin D ABCB1 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 21837:[DB00027 DB03166] DB00027|Gramicidin D ABCB1 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO2B1;SLC16A1 21838:[DB00027 DB01075] DB00027|Gramicidin D ABCB1 DB01075|Diphenhydramine HRH1;CHRM2;CYP2D6;CYP2C9;CYP2C19;CYP2C18;PTGS1;SLC22A2;SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1;SLC22A2 GO:0055085| transmembrane transport SLC22A5;ABCB1;SLC22A2 21839:[DB00027 DB07616] DB00027|Gramicidin D ABCB1 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways 21840:[DB00027 DB07136] DB00027|Gramicidin D ABCB1 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 21841:[DB00027 DB04576] DB00027|Gramicidin D ABCB1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 21842:[DB00027 DB02337] DB00027|Gramicidin D ABCB1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 21843:[DB00027 DB14641] DB00027|Gramicidin D ABCB1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes ABCB1 common pathways GO:0042493| response to drug ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0006810| transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 21844:[DB00027 DB00116] DB00027|Gramicidin D ABCB1 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0006810| transport ABCB1;ABCC2 GO:0042493| response to drug MTHFR;ABCB1;ABCC2 21845:[DB00027 DB02158] DB00027|Gramicidin D ABCB1 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 21846:[DB00027 DB05033] DB00027|Gramicidin D ABCB1 DB05033|INCB7839 ADAM9 common genes common pathways 21847:[DB00027 DB13998] DB00027|Gramicidin D ABCB1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0042493| response to drug CALR;ABCB1 21848:[DB00027 DB08835] DB00027|Gramicidin D ABCB1 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 21849:[DB00027 DB05460] DB00027|Gramicidin D ABCB1 DB05460|Ezatiostat GSTP1 common genes common pathways 21850:[DB00027 DB03288] DB00027|Gramicidin D ABCB1 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways 21851:[DB00027 DB05299] DB00027|Gramicidin D ABCB1 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways 21852:[DB00027 DB00611] DB00027|Gramicidin D ABCB1 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways 21853:[DB00027 DB02105] DB00027|Gramicidin D ABCB1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0042493| response to drug ABCB1;COMT 21854:[DB00027 DB09072] DB00027|Gramicidin D ABCB1 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways 21855:[DB00027 DB13988] DB00027|Gramicidin D ABCB1 DB13988|SB-269970 HTR7 common genes common pathways 21856:[DB00027 DB01049] DB00027|Gramicidin D ABCB1 DB01049|Ergoloid mesylate DRD1;DRD5;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;HTR2A;HTR1B;ABCB1;DRD2;ADRA1A;HTR2C;HTR2B;DRD3 21857:[DB00027 DB11726] DB00027|Gramicidin D ABCB1 DB11726|Encenicline CHRNA7 common genes common pathways 21858:[DB00027 DB00745] DB00027|Gramicidin D ABCB1 DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0042493| response to drug SLC6A3;ABCB1;CYP1A2 21859:[DB00027 DB04657] DB00027|Gramicidin D ABCB1 DB04657|Carboxin SDHA common genes common pathways 21860:[DB00027 DB01234] DB00027|Gramicidin D ABCB1 DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug CYP2E1;ABCG2;ANXA1;ABCC2;ABCB1;CYP1A1 GO:0006810| transport ABCB1;ABCG2;ABCC2;ABCB11 GO:0055085| transmembrane transport ABCB1;ABCC2;ABCG2;SLCO1A2;ABCB11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1;NR1I2 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCB1 21861:[DB00027 DB00779] DB00027|Gramicidin D ABCB1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1 21862:[DB00027 DB01086] DB00027|Gramicidin D ABCB1 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport SCN10A;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 21863:[DB00027 DB00858] DB00027|Gramicidin D ABCB1 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0006810| transport ABCB1;AR 21864:[DB00027 DB01562] DB00027|Gramicidin D ABCB1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways 21865:[DB00027 DB06554] DB00027|Gramicidin D ABCB1 DB06554|Gaboxadol SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 21866:[DB00027 DB02853] DB00027|Gramicidin D ABCB1 DB02853|D-Proline SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 21867:[DB00027 DB04275] DB00027|Gramicidin D ABCB1 DB04275|N-acetylserotonin SPR common genes common pathways 21868:[DB00027 DB00016] DB00027|Gramicidin D ABCB1 DB00016|Erythropoietin EPOR common genes common pathways 21869:[DB00027 DB13875] DB00027|Gramicidin D ABCB1 DB13875|Harmaline HNMT common genes common pathways 21870:[DB00027 DB06704] DB00027|Gramicidin D ABCB1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 21871:[DB00027 DB07757] DB00027|Gramicidin D ABCB1 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways 21872:[DB00027 DB09322] DB00027|Gramicidin D ABCB1 DB09322|Zinc sulfate ALPPL2 common genes common pathways 21873:[DB00027 DB08553] DB00027|Gramicidin D ABCB1 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways 21874:[DB00027 DB07544] DB00027|Gramicidin D ABCB1 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways 21875:[DB00027 DB00142] DB00027|Gramicidin D ABCB1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0042493| response to drug GCLM;SLC1A2;SLC1A3;GAD2;ABAT;GAD1;ABCB1;PFAS;GRIN2A GO:0055085| transmembrane transport ABCB1;GRIK4;GRIK5;GRIK3;SLC1A7;SLC25A18;SLC25A22;GRIK1;SLC16A1;SLC16A10;GRIK2 GO:0006810| transport GRIN2B;GRIK2;GRIA3;GRIN2A;GRIK1;GRID2;GRIA4;GRIN2C;ABCB1;GRIK4 21876:[DB00027 DB07444] DB00027|Gramicidin D ABCB1 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways 21877:[DB00027 DB00593] DB00027|Gramicidin D ABCB1 DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055085| transmembrane transport ABCB1;CACNA1G 21878:[DB00027 DB06594] DB00027|Gramicidin D ABCB1 DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0042493| response to drug HTR2C;ABCB1;CYP1A2 21879:[DB00027 DB00599] DB00027|Gramicidin D ABCB1 DB00599|Thiopental GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;FAAH;CHRM3;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006810| transport ABCB1;GABRA5;GABRA3;GABRA1;GRIK2;GABRA6;GABRA4 21880:[DB00027 DB06680] DB00027|Gramicidin D ABCB1 DB06680|Asoprisnil PGR common genes common pathways 21881:[DB00027 DB00486] DB00027|Gramicidin D ABCB1 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 21882:[DB00027 DB05120] DB00027|Gramicidin D ABCB1 DB05120|AT1391 INSR common genes common pathways 21883:[DB00027 DB09207] DB00027|Gramicidin D ABCB1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD3;DRD2;ABCB1 21884:[DB00027 DB04094] DB00027|Gramicidin D ABCB1 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways 21885:[DB00027 DB00198] DB00027|Gramicidin D ABCB1 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0006810| transport SLC15A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;ABCC4;SLC22A8 GO:0042493| response to drug ABCB1;ABCC4 21886:[DB00027 DB00188] DB00027|Gramicidin D ABCB1 DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 GO:0055085| transmembrane transport PSMB5;PSMB1;ABCB1 21887:[DB00027 DB08871] DB00027|Gramicidin D ABCB1 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0055085| transmembrane transport BCL2;ABCB1 GO:0042493| response to drug BCL2;ABCB1 21888:[DB00027 DB05996] DB00027|Gramicidin D ABCB1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways 21889:[DB00027 DB05915] DB00027|Gramicidin D ABCB1 DB05915|MYO-029 MSTN common genes common pathways 21890:[DB00027 DB00304] DB00027|Gramicidin D ABCB1 DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways 21891:[DB00027 DB09223] DB00027|Gramicidin D ABCB1 DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0042493| response to drug HTR2A;DRD2;ABCB1;DRD3 21892:[DB00027 DB07981] DB00027|Gramicidin D ABCB1 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways 21893:[DB00027 DB09285] DB00027|Gramicidin D ABCB1 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;TBXA2R;PTGS2 21894:[DB00027 DB03048] DB00027|Gramicidin D ABCB1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways 21895:[DB00027 DB01106] DB00027|Gramicidin D ABCB1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways 21896:[DB00027 DB01210] DB00027|Gramicidin D ABCB1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways 21897:[DB00027 DB02556] DB00027|Gramicidin D ABCB1 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:0006810| transport SLC7A5;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC16A10 GO:0042493| response to drug CRH;ABCB1 21898:[DB00027 DB06217] DB00027|Gramicidin D ABCB1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0055085| transmembrane transport KCND3;SCN5A;KCNH2;ABCB1;KCNA5 21899:[DB00027 DB02570] DB00027|Gramicidin D ABCB1 DB02570|PD150606 CAPNS1 common genes common pathways 21900:[DB00027 DB07960] DB00027|Gramicidin D ABCB1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways 21901:[DB00027 DB02266] DB00027|Gramicidin D ABCB1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0006810| transport ABCB1;TTR;AR GO:0055085| transmembrane transport ABCB1;SLC22A6 21902:[DB00027 DB02377] DB00027|Gramicidin D ABCB1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0042493| response to drug ABCB1;PNP 21903:[DB00027 DB12305] DB00027|Gramicidin D ABCB1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0055085| transmembrane transport SLC6A4;SLC6A3;ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A4;ABCB1;SLC6A3;SLC6A2 21904:[DB00027 DB01209] DB00027|Gramicidin D ABCB1 DB01209|Dezocine OPRM1;OPRK1 common genes common pathways 21905:[DB00027 DB01619] DB00027|Gramicidin D ABCB1 DB01619|Phenindamine HRH1 common genes common pathways 21906:[DB00027 DB05892] DB00027|Gramicidin D ABCB1 DB05892|RI 624 NGF common genes common pathways 21907:[DB00027 DB07425] DB00027|Gramicidin D ABCB1 DB07425|Sobetirome THRB common genes common pathways 21908:[DB00027 DB02942] DB00027|Gramicidin D ABCB1 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 21909:[DB00027 DB08992] DB00027|Gramicidin D ABCB1 DB08992|Eperisone CYP3A4 common genes common pathways 21910:[DB00027 DB12752] DB00027|Gramicidin D ABCB1 DB12752|Bucindolol CYP2D6 common genes common pathways 21911:[DB00027 DB11251] DB00027|Gramicidin D ABCB1 DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0042493| response to drug ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006810| transport TTPA;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 21912:[DB00027 DB01577] DB00027|Gramicidin D ABCB1 DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A3;SLC18A1;SLC22A5 GO:0042493| response to drug ABCB1;SLC6A3;MAOB;SLC6A2;SLC6A4 GO:0055085| transmembrane transport SLC6A4;SLC22A5;SLC18A2;SLC18A1;SLC22A3;SLC6A3;ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 21913:[DB00027 DB11723] DB00027|Gramicidin D ABCB1 DB11723|Dutogliptin DPP4 common genes common pathways 21914:[DB00027 DB04153] DB00027|Gramicidin D ABCB1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways 21915:[DB00027 DB00051] DB00027|Gramicidin D ABCB1 DB00051|Adalimumab TNF common genes common pathways 21916:[DB00027 DB05740] DB00027|Gramicidin D ABCB1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways 21917:[DB00027 DB03756] DB00027|Gramicidin D ABCB1 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0042493| response to drug PPARG;SREBF1;ABCB1 21918:[DB00027 DB00399] DB00027|Gramicidin D ABCB1 DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 common genes common pathways GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 21919:[DB00027 DB06362] DB00027|Gramicidin D ABCB1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 21920:[DB00027 DB04768] DB00027|Gramicidin D ABCB1 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 21921:[DB00027 DB03052] DB00027|Gramicidin D ABCB1 DB03052|Dazoxiben TBXAS1 common genes common pathways 21922:[DB00027 DB00437] DB00027|Gramicidin D ABCB1 DB00437|Allopurinol XDH;AOX1;XDH;SLC22A8;SLC22A7 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8;SLC22A7 21923:[DB00027 DB01024] DB00027|Gramicidin D ABCB1 DB01024|Mycophenolic acid IMPDH1;IMPDH2;UGT1A1;UGT1A9;UGT2B7;UGT1A7;UGT1A6 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 21924:[DB00027 DB00473] DB00027|Gramicidin D ABCB1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCB1;SCN10A 21925:[DB00027 DB00441] DB00027|Gramicidin D ABCB1 DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0055085| transmembrane transport ABCC10;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug TYMS;ABCB1 GO:1901529| ABCB1 21926:[DB00027 DB02467] DB00027|Gramicidin D ABCB1 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways 21927:[DB00027 DB01046] DB00027|Gramicidin D ABCB1 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CLCN2 GO:0006810| transport ABCB1;CLCN2 21928:[DB00027 DB08103] DB00027|Gramicidin D ABCB1 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 21929:[DB00027 DB03147] DB00027|Gramicidin D ABCB1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0042493| response to drug MAOB;POR;ABCB1 21930:[DB00027 DB00235] DB00027|Gramicidin D ABCB1 DB00235|Milrinone PDE3A common genes common pathways GO:0042493| response to drug PDE3A;ABCB1 21931:[DB00027 DB03485] DB00027|Gramicidin D ABCB1 DB03485|Alpha-D-Fucose LTF common genes common pathways 21932:[DB00027 DB00540] DB00027|Gramicidin D ABCB1 DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCB1 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A4;HTR2A;CYP2E1;CYP1A2;HTR2C;DRD2;ADRA1A;ABCB1;SLC6A2 21933:[DB00027 DB14562] DB00027|Gramicidin D ABCB1 DB14562|Andexanet alfa TFPI common genes common pathways 21934:[DB00027 DB08824] DB00027|Gramicidin D ABCB1 DB08824|Ioflupane I-123 SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A3;ABCB1 GO:0055085| transmembrane transport SLC6A3;ABCB1 21935:[DB00027 DB05252] DB00027|Gramicidin D ABCB1 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways 21936:[DB00027 DB03701] DB00027|Gramicidin D ABCB1 DB03701|Vanoxerine SLC6A3;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0042493| response to drug SLC6A3;ABCB1 21937:[DB00027 DB07168] DB00027|Gramicidin D ABCB1 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways 21938:[DB00027 DB08995] DB00027|Gramicidin D ABCB1 DB08995|Diosmin AHR common genes common pathways 21939:[DB00027 DB01390] DB00027|Gramicidin D ABCB1 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways GO:0006810| transport SLC4A4;ABCB1 GO:0055085| transmembrane transport SLC4A8;ABCB1;SLC4A7;SLC4A4 21940:[DB00027 DB06717] DB00027|Gramicidin D ABCB1 DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways 21941:[DB00027 DB02545] DB00027|Gramicidin D ABCB1 DB02545|Fexaramine NR1H4 common genes common pathways 21942:[DB00027 DB03619] DB00027|Gramicidin D ABCB1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCB11;SLC10A2;SLC10A1;ABCB1 GO:0006810| transport ABCB1;SLC10A2;SLC10A1;ABCB11 21943:[DB00027 DB06374] DB00027|Gramicidin D ABCB1 DB06374|Elacestrant ESR1 common genes common pathways 21944:[DB00027 DB00404] DB00027|Gramicidin D ABCB1 DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:0006810| transport GABRG2;GABRB1;GABRA6;GABRA4;GABRA1;GABRB3;GABRA5;GABRA3;GABRB2;GABRD;ABCB1 GO:0042493| response to drug ABCB1;GABRG3 21945:[DB00027 DB01723] DB00027|Gramicidin D ABCB1 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways 21946:[DB00027 DB01407] DB00027|Gramicidin D ABCB1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 21947:[DB00027 DB01439] DB00027|Gramicidin D ABCB1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 21948:[DB00027 DB00072] DB00027|Gramicidin D ABCB1 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways 21949:[DB00027 DB07497] DB00027|Gramicidin D ABCB1 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways 21950:[DB00027 DB01411] DB00027|Gramicidin D ABCB1 DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0042493| response to drug ABCB1;ABCC2 GO:0006810| transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCC2 21951:[DB00027 DB00041] DB00027|Gramicidin D ABCB1 DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 21952:[DB00027 DB09555] DB00027|Gramicidin D ABCB1 DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC22A1 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1 21953:[DB00027 DB05790] DB00027|Gramicidin D ABCB1 DB05790|SR 140333 TACR1 common genes common pathways 21954:[DB00027 DB01429] DB00027|Gramicidin D ABCB1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CALM1;SCN5A 21955:[DB00027 DB09338] DB00027|Gramicidin D ABCB1 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0042493| response to drug ABCB1;AQP1 GO:0055085| transmembrane transport ABCB1;SLC16A1;AQP1 21956:[DB00027 DB00379] DB00027|Gramicidin D ABCB1 DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1 21957:[DB00027 DB07315] DB00027|Gramicidin D ABCB1 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways 21958:[DB00027 DB09418] DB00027|Gramicidin D ABCB1 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways GO:0055085| transmembrane transport SLC5A5;ABCB1 GO:0006810| transport ABCB1;SLC5A5 21959:[DB00027 DB00526] DB00027|Gramicidin D ABCB1 DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0042493| response to drug CYP2E1;SOD1;ABCG2;ABCC2;ABCB1;CYP1A1 GO:0055085| transmembrane transport SLC22A3;ABCB1;SLC22A2;ABCC2;ABCG2 GO:0006810| transport ABCC2;ABCG2;ABCB1 GO:0006855| drug transmembrane transport SLC22A3;ABCB1;ABCG2;SLC22A2;ABCC2;SLC31A1 GO:0042908| xenobiotic transport ABCB1;ABCG2 21960:[DB00027 DB04636] DB00027|Gramicidin D ABCB1 DB04636|Glutamine t-butyl ester QPCT common genes common pathways 21961:[DB00027 DB04676] DB00027|Gramicidin D ABCB1 DB04676|Dansyllysine IGHA2 common genes common pathways 21962:[DB00027 DB05254] DB00027|Gramicidin D ABCB1 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways 21963:[DB00027 DB03276] DB00027|Gramicidin D ABCB1 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways 21964:[DB00027 DB01127] DB00027|Gramicidin D ABCB1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0042908| xenobiotic transport ABCB1;NR1I2 21965:[DB00027 DB12952] DB00027|Gramicidin D ABCB1 DB12952|Methylprednisone CYP3A4 common genes common pathways 21966:[DB00027 DB02552] DB00027|Gramicidin D ABCB1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways 21967:[DB00027 DB08699] DB00027|Gramicidin D ABCB1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways 21968:[DB00027 DB00380] DB00027|Gramicidin D ABCB1 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways 21969:[DB00027 DB07916] DB00027|Gramicidin D ABCB1 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways 21970:[DB00027 DB03800] DB00027|Gramicidin D ABCB1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways GO:0042493| response to drug ABCB1;TYMS 21971:[DB00027 DB03956] DB00027|Gramicidin D ABCB1 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways 21972:[DB00027 DB02673] DB00027|Gramicidin D ABCB1 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways 21973:[DB00027 DB07356] DB00027|Gramicidin D ABCB1 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways 21974:[DB00027 DB05052] DB00027|Gramicidin D ABCB1 DB05052|MF101 ESR2 common genes common pathways 21975:[DB00027 DB06243] DB00027|Gramicidin D ABCB1 DB06243|Eflornithine ODC1 common genes common pathways 21976:[DB00027 DB00195] DB00027|Gramicidin D ABCB1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 21977:[DB00027 DB04789] DB00027|Gramicidin D ABCB1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0006810| transport ABCC2;ABCB1 GO:0042493| response to drug ABCB1;ABCC2 GO:0006855| drug transmembrane transport ABCC2;ABCB1 21978:[DB00027 DB01452] DB00027|Gramicidin D ABCB1 DB01452|Diamorphine OPRM1;OPRK1;OPRD1;CES1 common genes common pathways 21979:[DB00027 DB09288] DB00027|Gramicidin D ABCB1 DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes common pathways GO:0055085| transmembrane transport ABCB1;TRPV1 GO:0006810| transport ABCB1;TRPV1 GO:0042493| response to drug BCHE;UGT1A1;ABCB1;CYP2E1;PTGS2;CYP1A2 21980:[DB00027 DB01363] DB00027|Gramicidin D ABCB1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC18A1 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A3;ABCB1;SLC6A2;SLC6A4;SLC18A2;SLC18A1 GO:0042493| response to drug SLC6A4;MAOB;SLC6A2;SLC6A3;ABCB1 21981:[DB00027 DB04540] DB00027|Gramicidin D ABCB1 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCG2;ABCB1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 21982:[DB00027 DB12445] DB00027|Gramicidin D ABCB1 DB12445|Nitroaspirin PTGS1 common genes common pathways 21983:[DB00027 DB00499] DB00027|Gramicidin D ABCB1 DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;CYP1A2 GO:0006810| transport AR;ABCB1 GO:0042908| xenobiotic transport ABCB1;NR1I2 21984:[DB00027 DB14540] DB00027|Gramicidin D ABCB1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug HSD11B2;ANXA1;ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 21985:[DB00027 DB01369] DB00027|Gramicidin D ABCB1 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways 21986:[DB00027 DB00474] DB00027|Gramicidin D ABCB1 DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways GO:0006810| transport GABRA1;ABCB1 21987:[DB00027 DB00557] DB00027|Gramicidin D ABCB1 DB00557|Hydroxyzine HRH1;CYP2D6 common genes common pathways 21988:[DB00027 DB01351] DB00027|Gramicidin D ABCB1 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport GABRA1;GABRA4;GABRA6;GRIK2;GABRA5;GABRA3;ABCB1 21989:[DB00027 DB07421] DB00027|Gramicidin D ABCB1 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways GO:0006810| transport ABCB1;AR 21990:[DB00027 DB01380] DB00027|Gramicidin D ABCB1 DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways 21991:[DB00027 DB00435] DB00027|Gramicidin D ABCB1 DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 21992:[DB00027 DB13872] DB00027|Gramicidin D ABCB1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0006810| transport GABRA5;GABRA3;ABCB1;GABRA1;GABRG2 21993:[DB00027 DB14503] DB00027|Gramicidin D ABCB1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0042493| response to drug SLC34A1;ABCB1 GO:0055085| transmembrane transport SLC20A2;SLC34A3;SLC20A1;ABCB1;SLC34A2 GO:0006810| transport ABCB1;SLC20A2;SLC20A1 21994:[DB00027 DB02029] DB00027|Gramicidin D ABCB1 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways 21995:[DB00027 DB03896] DB00027|Gramicidin D ABCB1 DB03896|Triphosphoric acid PAPOLA common genes common pathways 21996:[DB00027 DB06190] DB00027|Gramicidin D ABCB1 DB06190|Solabegron ADRB3 common genes common pathways 21997:[DB00027 DB06787] DB00027|Gramicidin D ABCB1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 21998:[DB00027 DB03860] DB00027|Gramicidin D ABCB1 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways 21999:[DB00027 DB06652] DB00027|Gramicidin D ABCB1 DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways 22000:[DB00027 DB06412] DB00027|Gramicidin D ABCB1 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0006810| transport ABCB1;AR GO:0042493| response to drug ABCB1;SRD5A1 22001:[DB00027 DB01228] DB00027|Gramicidin D ABCB1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCB1 22002:[DB00027 DB02559] DB00027|Gramicidin D ABCB1 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways 22003:[DB00027 DB00604] DB00027|Gramicidin D ABCB1 DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2A;ABCB1 GO:0055085| transmembrane transport KCNH2;ABCB1 22004:[DB00027 DB02222] DB00027|Gramicidin D ABCB1 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1 22005:[DB00027 DB07111] DB00027|Gramicidin D ABCB1 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 22006:[DB00027 DB06241] DB00027|Gramicidin D ABCB1 DB06241|Clenoliximab CD4 common genes common pathways 22007:[DB00027 DB01138] DB00027|Gramicidin D ABCB1 DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1;ABCC3 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCC3;NR1I2;ABCB1 GO:0055085| transmembrane transport ABCB11;SLC22A12;ABCC4;ABCC3;ABCC6;ABCC1;ABCC2;ABCC5;ABCB1 GO:0006810| transport ABCB11;ABCB1;ABCC5;ABCC2;ABCC1;ABCC3;ABCC6 GO:0042493| response to drug SLC22A12;ABCC4;ABCC6;ABCC1;ABCC2;ABCB1 22008:[DB00027 DB06713] DB00027|Gramicidin D ABCB1 DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0006810| transport AR;ABCB1 22009:[DB00027 DB02126] DB00027|Gramicidin D ABCB1 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways 22010:[DB00027 DB01252] DB00027|Gramicidin D ABCB1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0042493| response to drug PPARG;ABCB1;ABCC8 GO:0055085| transmembrane transport ABCC8;ABCB1 22011:[DB00027 DB00814] DB00027|Gramicidin D ABCB1 DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways GO:0042493| response to drug ABCB1;ABCC4;PTGS2 GO:0055085| transmembrane transport ABCC4;ABCB1 22012:[DB00027 DB06262] DB00027|Gramicidin D ABCB1 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0042493| response to drug SLC6A2;ADRA1A;ABCB1 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A2;SLC16A10 22013:[DB00027 DB08214] DB00027|Gramicidin D ABCB1 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways 22014:[DB00027 DB01059] DB00027|Gramicidin D ABCB1 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A5 GO:0042493| response to drug CYP1A1;ABCB1;CYP1A2 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 22015:[DB00027 DB02779] DB00027|Gramicidin D ABCB1 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways 22016:[DB00027 DB05303] DB00027|Gramicidin D ABCB1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways 22017:[DB00027 DB07171] DB00027|Gramicidin D ABCB1 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways 22018:[DB00027 DB00002] DB00027|Gramicidin D ABCB1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 22019:[DB00027 DB02701] DB00027|Gramicidin D ABCB1 DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug LDHA;ABCB1;CYP2E1 22020:[DB00027 DB09146] DB00027|Gramicidin D ABCB1 DB09146|Iron saccharate HBA1;TF common genes common pathways 22021:[DB00027 DB09449] DB00027|Gramicidin D ABCB1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0042493| response to drug ABCB1;SLC34A1 GO:0006810| transport SLC20A1;SLC20A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC34A2;SLC34A3;SLC20A2;SLC20A1 22022:[DB00027 DB00533] DB00027|Gramicidin D ABCB1 DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0042493| response to drug ABCC4;CYP1A2;PTGS2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC4 22023:[DB00027 DB00083] DB00027|Gramicidin D ABCB1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 22024:[DB00027 DB02201] DB00027|Gramicidin D ABCB1 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 22025:[DB00027 DB13269] DB00027|Gramicidin D ABCB1 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0055085| transmembrane transport SCN10A;SCN4A;ABCB1;SCN2A;SCN3A;SCN9A;SCN8A;SCN11A;SCN5A;SCN7A;SCN1A GO:0042493| response to drug SCN11A;ABCB1 22026:[DB00027 DB07146] DB00027|Gramicidin D ABCB1 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways GO:0042493| response to drug LCK;ABCB1 22027:[DB00027 DB07975] DB00027|Gramicidin D ABCB1 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 22028:[DB00027 DB13775] DB00027|Gramicidin D ABCB1 DB13775|Tertatolol CYP2D6 common genes common pathways 22029:[DB00027 DB08213] DB00027|Gramicidin D ABCB1 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways GO:0042493| response to drug CASP3;ABCB1 22030:[DB00027 DB09200] DB00027|Gramicidin D ABCB1 DB09200|Rivoglitazone CYP3A4;CYP2C8 common genes common pathways 22031:[DB00027 DB13950] DB00027|Gramicidin D ABCB1 DB13950|WIN 55212-2 CYP3A4 common genes common pathways 22032:[DB00027 DB01395] DB00027|Gramicidin D ABCB1 DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways GO:0006810| transport AR;ABCB1 GO:0042493| response to drug PTGS2;BCHE;ABCB1 22033:[DB00027 DB01126] DB00027|Gramicidin D ABCB1 DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;SRD5A2;SRD5A1 22034:[DB00027 DB06370] DB00027|Gramicidin D ABCB1 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 22035:[DB00027 DB03693] DB00027|Gramicidin D ABCB1 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways 22036:[DB00027 DB13866] DB00027|Gramicidin D ABCB1 DB13866|Etynodiol CYP3A4 common genes common pathways 22037:[DB00027 DB02624] DB00027|Gramicidin D ABCB1 DB02624|Homoserine Lactone SLC9A1 common genes common pathways GO:0055085| transmembrane transport SLC9A1;ABCB1 22038:[DB00027 DB11348] DB00027|Gramicidin D ABCB1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0042493| response to drug CALR;ABCB1;SLC34A1;SLC8A1 GO:0055085| transmembrane transport SLC34A2;CACNA1F;RYR2;CACNA1I;ABCB1;CACNA1A;TRPV6;CACNA1E;RYR3;TRPV5;CACNA1S;CATSPER1;CACNA1G;SLC20A2;CALM1;CACNA1C;RYR1;SLC34A3;SLC8A1;CACNA1D;SLC20A1;CACNA1H GO:0006810| transport CACNB4;SLC20A2;SRI;SLC20A1;ABCB1;CACNA1I;CACNB1;CACNA1E;CACNB3 22039:[DB00027 DB09389] DB00027|Gramicidin D ABCB1 DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0006810| transport ABCB1;AR GO:0042493| response to drug SRD5A1;ABCB1 22040:[DB00027 DB12191] DB00027|Gramicidin D ABCB1 DB12191|Obatoclax BCL2 common genes common pathways GO:0055085| transmembrane transport BCL2;ABCB1 GO:0042493| response to drug ABCB1;BCL2 22041:[DB00027 DB04352] DB00027|Gramicidin D ABCB1 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 22042:[DB00027 DB03727] DB00027|Gramicidin D ABCB1 DB03727|Coproporphyrin I UROD common genes common pathways 22043:[DB00027 DB08807] DB00027|Gramicidin D ABCB1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0042493| response to drug HTR1B;ABCB1 22044:[DB00027 DB08406] DB00027|Gramicidin D ABCB1 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways 22045:[DB00027 DB11130] DB00027|Gramicidin D ABCB1 DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0042493| response to drug ABCB1;B2M 22046:[DB00027 DB00578] DB00027|Gramicidin D ABCB1 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 22047:[DB00027 DB08461] DB00027|Gramicidin D ABCB1 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways GO:0006810| transport ABCB1;AR 22048:[DB00027 DB08751] DB00027|Gramicidin D ABCB1 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways 22049:[DB00027 DB07172] DB00027|Gramicidin D ABCB1 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 22050:[DB00027 DB00589] DB00027|Gramicidin D ABCB1 DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2C;HTR2B;ABCB1;HTR1B;DRD2;DRD3;DRD1;HTR2A 22051:[DB00027 DB09502] DB00027|Gramicidin D ABCB1 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0055085| transmembrane transport SLC2A8;SLC2A1;SLC2A3;SLC2A12;SLC2A9;SLC2A6;SLC2A11;SLC2A7;SLC2A4;SLC2A2;ABCB1;SLC2A10;SLC2A5 GO:0042908| xenobiotic transport SLC2A1;ABCB1 22052:[DB00027 DB01070] DB00027|Gramicidin D ABCB1 DB01070|Dihydrotachysterol VDR common genes common pathways 22053:[DB00027 DB04683] DB00027|Gramicidin D ABCB1 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways 22054:[DB00027 DB05505] DB00027|Gramicidin D ABCB1 DB05505|NM-702 TBXAS1 common genes common pathways 22055:[DB00027 DB02763] DB00027|Gramicidin D ABCB1 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways 22056:[DB00027 DB01240] DB00027|Gramicidin D ABCB1 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways 22057:[DB00027 DB08847] DB00027|Gramicidin D ABCB1 DB08847|Hydroxyproline SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 22058:[DB00027 DB02383] DB00027|Gramicidin D ABCB1 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways 22059:[DB00027 DB11607] DB00027|Gramicidin D ABCB1 DB11607|Efmoroctocog alfa VWF common genes common pathways 22060:[DB00027 DB04825] DB00027|Gramicidin D ABCB1 DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CALM1;ABCB1 22061:[DB00027 DB00152] DB00027|Gramicidin D ABCB1 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0055085| transmembrane transport SLC22A5;SLC22A1;SLC22A2;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCB1;SLC22A5 22062:[DB00027 DB04964] DB00027|Gramicidin D ABCB1 DB04964|Oregovomab MUC16 common genes common pathways 22063:[DB00027 DB05476] DB00027|Gramicidin D ABCB1 DB05476|WX-UK1 PLAUR common genes common pathways 22064:[DB00027 DB09029] DB00027|Gramicidin D ABCB1 DB09029|Secukinumab IL17A common genes common pathways 22065:[DB00027 DB00097] DB00027|Gramicidin D ABCB1 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways 22066:[DB00027 DB00210] DB00027|Gramicidin D ABCB1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22067:[DB00027 DB05421] DB00027|Gramicidin D ABCB1 DB05421|CP-122721 TACR1 common genes common pathways 22068:[DB00027 DB01155] DB00027|Gramicidin D ABCB1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22069:[DB00027 DB06921] DB00027|Gramicidin D ABCB1 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 22070:[DB00027 DB05431] DB00027|Gramicidin D ABCB1 DB05431|MLN-977 ALOX5 common genes common pathways 22071:[DB00027 DB02998] DB00027|Gramicidin D ABCB1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0006810| transport ABCB1;AR 22072:[DB00027 DB14635] DB00027|Gramicidin D ABCB1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug CYP1A2;ABCB1;PPARG GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC5 GO:0006810| transport ABCC5;ABCB1 22073:[DB00027 DB11712] DB00027|Gramicidin D ABCB1 DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0055085| transmembrane transport CFTR;ABCB1 22074:[DB00027 DB02813] DB00027|Gramicidin D ABCB1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways 22075:[DB00027 DB04318] DB00027|Gramicidin D ABCB1 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways 22076:[DB00027 DB02142] DB00027|Gramicidin D ABCB1 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways 22077:[DB00027 DB12334] DB00027|Gramicidin D ABCB1 DB12334|Milataxel TUBB1;TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 22078:[DB00027 DB06157] DB00027|Gramicidin D ABCB1 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 22079:[DB00027 DB07462] DB00027|Gramicidin D ABCB1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0042493| response to drug ABCB1;COMT 22080:[DB00027 DB09303] DB00027|Gramicidin D ABCB1 DB09303|Evolocumab PCSK9 common genes common pathways 22081:[DB00027 DB01284] DB00027|Gramicidin D ABCB1 DB01284|Tetracosactide MC2R common genes common pathways 22082:[DB00027 DB05913] DB00027|Gramicidin D ABCB1 DB05913|OSI-930 KIT;FLT1 common genes common pathways 22083:[DB00027 DB00438] DB00027|Gramicidin D ABCB1 DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A5;SLC15A2;ABCB1;SLC22A6;SLC15A1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 22084:[DB00027 DB06124] DB00027|Gramicidin D ABCB1 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways 22085:[DB00027 DB12200] DB00027|Gramicidin D ABCB1 DB12200|Tivantinib MET common genes common pathways 22086:[DB00027 DB06366] DB00027|Gramicidin D ABCB1 DB06366|Pertuzumab ERBB2 common genes common pathways 22087:[DB00027 DB04590] DB00027|Gramicidin D ABCB1 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways 22088:[DB00027 DB05668] DB00027|Gramicidin D ABCB1 DB05668|Palifosfamide DNMT1 common genes common pathways 22089:[DB00027 DB04758] DB00027|Gramicidin D ABCB1 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways 22090:[DB00027 DB06101] DB00027|Gramicidin D ABCB1 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways 22091:[DB00027 DB04461] DB00027|Gramicidin D ABCB1 DB04461|Coproporphyrinogen III UROD common genes common pathways 22092:[DB00027 DB07039] DB00027|Gramicidin D ABCB1 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways GO:0006810| transport AR;ABCB1 22093:[DB00027 DB11059] DB00027|Gramicidin D ABCB1 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLC2A1;ABCB1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 22094:[DB00027 DB04325] DB00027|Gramicidin D ABCB1 DB04325|Phenethylamine PRSS2;PRSS1 common genes common pathways 22095:[DB00027 DB03403] DB00027|Gramicidin D ABCB1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 22096:[DB00027 DB00685] DB00027|Gramicidin D ABCB1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22097:[DB00027 DB06237] DB00027|Gramicidin D ABCB1 DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways 22098:[DB00027 DB08497] DB00027|Gramicidin D ABCB1 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0042493| response to drug CASP3;ABCB1 22099:[DB00027 DB08155] DB00027|Gramicidin D ABCB1 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 22100:[DB00027 DB07428] DB00027|Gramicidin D ABCB1 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 22101:[DB00027 DB04074] DB00027|Gramicidin D ABCB1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A7;SLC16A1;SLC16A3;ABCB1 22102:[DB00027 DB03239] DB00027|Gramicidin D ABCB1 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways GO:0006810| transport ABCB1;TTR 22103:[DB00027 DB01102] DB00027|Gramicidin D ABCB1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways 22104:[DB00027 DB04843] DB00027|Gramicidin D ABCB1 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways 22105:[DB00027 DB07067] DB00027|Gramicidin D ABCB1 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways 22106:[DB00027 DB05191] DB00027|Gramicidin D ABCB1 DB05191|Atl146e ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;ABCB1 22107:[DB00027 DB01834] DB00027|Gramicidin D ABCB1 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways 22108:[DB00027 DB00859] DB00027|Gramicidin D ABCB1 DB00859|Penicillamine SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;ABCB1 22109:[DB00027 DB12458] DB00027|Gramicidin D ABCB1 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways GO:0006810| transport GABRG2;GABRA1;GABRB3;ABCB1 22110:[DB00027 DB11703] DB00027|Gramicidin D ABCB1 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 22111:[DB00027 DB00655] DB00027|Gramicidin D ABCB1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug CYP1A1;ABCB1;ABCG2;CYP1A2;CYP2E1 GO:0006810| transport ABCG2;ABCB1;AR GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;SLCO1B1;SLC22A8;ABCB1;ABCG2;SLCO2B1 22112:[DB00027 DB00902] DB00027|Gramicidin D ABCB1 DB00902|Methdilazine HRH1 common genes common pathways 22113:[DB00027 DB05087] DB00027|Gramicidin D ABCB1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0006810| transport ABCB1;GABRA5;GABRA3;GABRA6;GABRA4;GABRA1 22114:[DB00027 DB00886] DB00027|Gramicidin D ABCB1 DB00886|Omapatrilat ACE;MME common genes common pathways 22115:[DB00027 DB01626] DB00027|Gramicidin D ABCB1 DB01626|Pargyline MAOB;MAOA common genes common pathways GO:0042493| response to drug MAOB;ABCB1 22116:[DB00027 DB05351] DB00027|Gramicidin D ABCB1 DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways GO:0006810| transport ABCB1;ATP4A 22117:[DB00027 DB14642] DB00027|Gramicidin D ABCB1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0042493| response to drug ABCC2;ABCB1 GO:0006810| transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1 22118:[DB00027 DB04865] DB00027|Gramicidin D ABCB1 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 22119:[DB00027 DB06536] DB00027|Gramicidin D ABCB1 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 22120:[DB00027 DB01081] DB00027|Gramicidin D ABCB1 DB01081|Diphenoxylate OPRM1;OPRD1 common genes common pathways 22121:[DB00027 DB01219] DB00027|Gramicidin D ABCB1 DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;RYR1 22122:[DB00027 DB09166] DB00027|Gramicidin D ABCB1 DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0006810| transport GABRG2;GABRA1;ABCB1;GABRA3 22123:[DB00027 DB08760] DB00027|Gramicidin D ABCB1 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 22124:[DB00027 DB12945] DB00027|Gramicidin D ABCB1 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22125:[DB00027 DB04889] DB00027|Gramicidin D ABCB1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0042493| response to drug SLC6A4;SLC6A2;MAOB;DRD2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A2;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 22126:[DB00027 DB00782] DB00027|Gramicidin D ABCB1 DB00782|Propantheline CHRM1 common genes common pathways 22127:[DB00027 DB00422] DB00027|Gramicidin D ABCB1 DB00422|Methylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A3;SLC6A2;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A4;SLC6A3;ABCB1;SLC6A2 22128:[DB00027 DB14508] DB00027|Gramicidin D ABCB1 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006810| transport GRIA3;ABCB1 22129:[DB00027 DB04872] DB00027|Gramicidin D ABCB1 DB04872|Osanetant TACR3 common genes common pathways 22130:[DB00027 DB04187] DB00027|Gramicidin D ABCB1 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways 22131:[DB00027 DB01569] DB00027|Gramicidin D ABCB1 DB01569|Formebolone HSD11B2 common genes common pathways GO:0042493| response to drug HSD11B2;ABCB1 22132:[DB00027 DB05434] DB00027|Gramicidin D ABCB1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0072089| stem cell proliferation ABCB1;FGF2 22133:[DB00027 DB01008] DB00027|Gramicidin D ABCB1 DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways 22134:[DB00027 DB06211] DB00027|Gramicidin D ABCB1 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 22135:[DB00027 DB00517] DB00027|Gramicidin D ABCB1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways 22136:[DB00027 DB08838] DB00027|Gramicidin D ABCB1 DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0006810| transport CACNA1B;CHRNA1;ASIC3;SLC7A7;ABCB1 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A2;SLC22A3;CACNA1B GO:0006855| drug transmembrane transport SLC22A3;SLC22A2;ABCB1;SLC22A1 22137:[DB00027 DB00131] DB00027|Gramicidin D ABCB1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0042493| response to drug CREB1;ADCY1;ABCB1;ACSL1 22138:[DB00027 DB00594] DB00027|Gramicidin D ABCB1 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0042493| response to drug AOC1;ABCB1 GO:0055085| transmembrane transport SLC9A1;SLC22A4;SLC22A2;ABCB1 GO:0006810| transport ABCB1;ASIC1 22139:[DB00027 DB06288] DB00027|Gramicidin D ABCB1 DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0042493| response to drug HTR2A;DRD2;ABCB1;DRD3 22140:[DB00027 DB00569] DB00027|Gramicidin D ABCB1 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways 22141:[DB00027 DB11358] DB00027|Gramicidin D ABCB1 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways 22142:[DB00027 DB09205] DB00027|Gramicidin D ABCB1 DB09205|Moxisylyte ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;BCHE common genes common pathways GO:0042493| response to drug BCHE;ADRA1A;ABCB1 22143:[DB00027 DB04066] DB00027|Gramicidin D ABCB1 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways 22144:[DB00027 DB09282] DB00027|Gramicidin D ABCB1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 22145:[DB00027 DB00630] DB00027|Gramicidin D ABCB1 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0006810| transport ABCB1;ATP6V1A 22146:[DB00027 DB00237] DB00027|Gramicidin D ABCB1 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006810| transport GABRA3;GABRA5;GABRB2;GABRD;ABCB1;GABRG2;GABRB1;GABRA1;GABRA4;GABRA6;GRIK2;GABRB3 22147:[DB00027 DB08326] DB00027|Gramicidin D ABCB1 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways 22148:[DB00027 DB08846] DB00027|Gramicidin D ABCB1 DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA GO:0055085| transmembrane transport SLC22A11;ABCB1;SLC22A6 GO:2001225| regulation of chloride transport CA7;ABCB1;CA2 GO:0042493| response to drug CYP2E1;CA9;CYP1A1;ABCB1 22149:[DB00027 DB03349] DB00027|Gramicidin D ABCB1 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways 22150:[DB00027 DB02872] DB00027|Gramicidin D ABCB1 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways GO:0042493| response to drug ABCB1;MDM2 22151:[DB00027 DB11094] DB00027|Gramicidin D ABCB1 DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways 22152:[DB00027 DB05418] DB00027|Gramicidin D ABCB1 DB05418|GW 597599 TACR1 common genes common pathways 22153:[DB00027 DB01080] DB00027|Gramicidin D ABCB1 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0042493| response to drug ABCB1;ABAT GO:0055085| transmembrane transport SLC36A1;ABCB1 22154:[DB00027 DB05218] DB00027|Gramicidin D ABCB1 DB05218|PN0621 TNF common genes common pathways 22155:[DB00027 DB07976] DB00027|Gramicidin D ABCB1 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 22156:[DB00027 DB09053] DB00027|Gramicidin D ABCB1 DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways 22157:[DB00027 DB02109] DB00027|Gramicidin D ABCB1 DB02109|Hadacidin purA;ADSSL1 common genes common pathways 22158:[DB00027 DB03415] DB00027|Gramicidin D ABCB1 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways 22159:[DB00027 DB06999] DB00027|Gramicidin D ABCB1 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways 22160:[DB00027 DB14018] DB00027|Gramicidin D ABCB1 DB14018|Bromotheophylline CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22161:[DB00027 DB00405] DB00027|Gramicidin D ABCB1 DB00405|Dexbrompheniramine HRH1 common genes common pathways 22162:[DB00027 DB00346] DB00027|Gramicidin D ABCB1 DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0042493| response to drug ADRA1A;ABCB1 22163:[DB00027 DB04883] DB00027|Gramicidin D ABCB1 DB04883|Darusentan EDNRA common genes common pathways 22164:[DB00027 DB00878] DB00027|Gramicidin D ABCB1 DB00878|Chlorhexidine HNMT;cat common genes common pathways 22165:[DB00027 DB09265] DB00027|Gramicidin D ABCB1 DB09265|Lixisenatide GLP1R common genes common pathways 22166:[DB00027 DB07621] DB00027|Gramicidin D ABCB1 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways 22167:[DB00027 DB11429] DB00027|Gramicidin D ABCB1 DB11429|Mibolerone AR common genes common pathways GO:0006810| transport AR;ABCB1 22168:[DB00027 DB05466] DB00027|Gramicidin D ABCB1 DB05466|R673 TACR1 common genes common pathways 22169:[DB00027 DB05752] DB00027|Gramicidin D ABCB1 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 22170:[DB00027 DB04805] DB00027|Gramicidin D ABCB1 DB04805|Virginiamycin S1 RPL37 common genes common pathways 22171:[DB00027 DB06460] DB00027|Gramicidin D ABCB1 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways 22172:[DB00027 DB01019] DB00027|Gramicidin D ABCB1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways 22173:[DB00027 DB13800] DB00027|Gramicidin D ABCB1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0055085| transmembrane transport ABCB1;CALM1 22174:[DB00027 DB04527] DB00027|Gramicidin D ABCB1 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways 22175:[DB00027 DB08613] DB00027|Gramicidin D ABCB1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0042493| response to drug HDAC4;ABCB1 22176:[DB00027 DB01496] DB00027|Gramicidin D ABCB1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0006810| transport GABRA4;GABRA6;GRIK2;GABRA1;ABCB1;GABRA3;GABRA5 GO:0055085| transmembrane transport ABCB1;GRIK2 22177:[DB00027 DB05194] DB00027|Gramicidin D ABCB1 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways 22178:[DB00027 DB04948] DB00027|Gramicidin D ABCB1 DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0055085| transmembrane transport SLC47A1;ABCB5;ABCB1 GO:0042493| response to drug ADRA1A;ABCB1;HTR2C;CYP1A2 GO:0042908| xenobiotic transport ABCB5;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC47A1;ABCB5 22179:[DB00027 DB11637] DB00027|Gramicidin D ABCB1 DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways 22180:[DB00027 DB13994] DB00027|Gramicidin D ABCB1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways GO:0006810| transport ABCB1;GABRA3 22181:[DB00027 DB00414] DB00027|Gramicidin D ABCB1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways 22182:[DB00027 DB02670] DB00027|Gramicidin D ABCB1 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways 22183:[DB00027 DB00565] DB00027|Gramicidin D ABCB1 DB00565|Cisatracurium CHRNA2 common genes common pathways 22184:[DB00027 DB06925] DB00027|Gramicidin D ABCB1 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways GO:0042493| response to drug LCK;ABCB1 22185:[DB00027 DB08502] DB00027|Gramicidin D ABCB1 DB08502|Capravirine CYP3A4 common genes common pathways 22186:[DB00027 DB05685] DB00027|Gramicidin D ABCB1 DB05685|FX06 CDH5 common genes common pathways 22187:[DB00027 DB00989] DB00027|Gramicidin D ABCB1 DB00989|Rivastigmine ACHE;BCHE;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;BCHE 22188:[DB00027 DB00494] DB00027|Gramicidin D ABCB1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;COMT 22189:[DB00027 DB01548] DB00027|Gramicidin D ABCB1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways 22190:[DB00027 DB06148] DB00027|Gramicidin D ABCB1 DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0042493| response to drug ADRA1A;DRD2;ABCB1;HTR2B;HTR2C;SLC6A3;SLC6A2;DRD3;SLC6A4;DRD1;CYP1A2;HTR2A GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 22191:[DB00027 DB12093] DB00027|Gramicidin D ABCB1 DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0042493| response to drug DRD2;ABCB1;DRD1 22192:[DB00027 DB11256] DB00027|Gramicidin D ABCB1 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways GO:0055085| transmembrane transport SLC46A1;ABCB1 22193:[DB00027 DB00315] DB00027|Gramicidin D ABCB1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0042493| response to drug CYP1A2;HTR1B;ABCB1 22194:[DB00027 DB11064] DB00027|Gramicidin D ABCB1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0006810| transport AR;ABCB1 22195:[DB00027 DB05044] DB00027|Gramicidin D ABCB1 DB05044|PSN357 PYGL common genes common pathways 22196:[DB00027 DB07720] DB00027|Gramicidin D ABCB1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways 22197:[DB00027 DB07694] DB00027|Gramicidin D ABCB1 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 22198:[DB00027 DB05201] DB00027|Gramicidin D ABCB1 DB05201|V24343 CNR1 common genes common pathways 22199:[DB00027 DB05451] DB00027|Gramicidin D ABCB1 DB05451|P54 NFKB2;NFKB1 common genes common pathways 22200:[DB00027 DB03566] DB00027|Gramicidin D ABCB1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A4;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 22201:[DB00027 DB09331] DB00027|Gramicidin D ABCB1 DB09331|Daratumumab CD38 common genes common pathways GO:0042493| response to drug ABCB1;CD38 22202:[DB00027 DB01337] DB00027|Gramicidin D ABCB1 DB01337|Pancuronium CHRNA2;CHRM2;CHRM3;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0042493| response to drug ABCB1;BCHE GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A1 22203:[DB00027 DB06111] DB00027|Gramicidin D ABCB1 DB06111|AB192 MPO common genes common pathways 22204:[DB00027 DB00008] DB00027|Gramicidin D ABCB1 DB00008|Peginterferon alfa-2a IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22205:[DB00027 DB01074] DB00027|Gramicidin D ABCB1 DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0042493| response to drug ABCB1;CPT1A 22206:[DB00027 DB04915] DB00027|Gramicidin D ABCB1 DB04915|Idronoxil ENOX2 common genes common pathways 22207:[DB00027 DB05091] DB00027|Gramicidin D ABCB1 DB05091|M0002 AVPR2 common genes common pathways 22208:[DB00027 DB06595] DB00027|Gramicidin D ABCB1 DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;CYP2E1 22209:[DB00027 DB08172] DB00027|Gramicidin D ABCB1 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 22210:[DB00027 DB00790] DB00027|Gramicidin D ABCB1 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug BCHE;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport SLC15A2;ABCB1;SLC15A1 22211:[DB00027 DB01962] DB00027|Gramicidin D ABCB1 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways GO:0042493| response to drug ABCB1;SRC 22212:[DB00027 DB01835] DB00027|Gramicidin D ABCB1 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways 22213:[DB00027 DB03419] DB00027|Gramicidin D ABCB1 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways 22214:[DB00027 DB01296] DB00027|Gramicidin D ABCB1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 22215:[DB00027 DB12866] DB00027|Gramicidin D ABCB1 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 22216:[DB00027 DB02974] DB00027|Gramicidin D ABCB1 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways 22217:[DB00027 DB00849] DB00027|Gramicidin D ABCB1 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0006810| transport GABRA3;GABRA5;ABCB1;GRIK2;GABRA6;GABRA4;GABRA1 GO:0055085| transmembrane transport ABCB1;GRIK2 22218:[DB00027 DB01412] DB00027|Gramicidin D ABCB1 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug ADORA2A;ABCB1;CYP2E1;CYP1A2 22219:[DB00027 DB04674] DB00027|Gramicidin D ABCB1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0006810| transport ABCB1;TTR 22220:[DB00027 DB13150] DB00027|Gramicidin D ABCB1 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways 22221:[DB00027 DB04827] DB00027|Gramicidin D ABCB1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways 22222:[DB00027 DB00521] DB00027|Gramicidin D ABCB1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways 22223:[DB00027 DB06842] DB00027|Gramicidin D ABCB1 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways 22224:[DB00027 DB00549] DB00027|Gramicidin D ABCB1 DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0042493| response to drug CYP2E1;CYP1A2;ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 22225:[DB00027 DB00531] DB00027|Gramicidin D ABCB1 DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 22226:[DB00027 DB05419] DB00027|Gramicidin D ABCB1 DB05419|ADX-10061 CALY common genes common pathways 22227:[DB00027 DB07695] DB00027|Gramicidin D ABCB1 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways GO:0006810| transport ABCB1;TTR 22228:[DB00027 DB07851] DB00027|Gramicidin D ABCB1 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways 22229:[DB00027 DB06700] DB00027|Gramicidin D ABCB1 DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCB1 GO:0042493| response to drug SLC6A4;SLC6A2;ABCB1 22230:[DB00027 DB06782] DB00027|Gramicidin D ABCB1 DB06782|Dimercaprol APP common genes common pathways 22231:[DB00027 DB00852] DB00027|Gramicidin D ABCB1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;SLC6A2 GO:0006810| transport ABCB1;SLC6A2 GO:0042493| response to drug SLC6A4;JUN;SLC6A3;ADRA1A;ABCB1;FOS;SLC6A2 22232:[DB00027 DB03083] DB00027|Gramicidin D ABCB1 DB03083|IC261 CSNK1G2 common genes common pathways 22233:[DB00027 DB02773] DB00027|Gramicidin D ABCB1 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways 22234:[DB00027 DB06769] DB00027|Gramicidin D ABCB1 DB06769|Bendamustine CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22235:[DB00027 DB05022] DB00027|Gramicidin D ABCB1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways 22236:[DB00027 DB00192] DB00027|Gramicidin D ABCB1 DB00192|Indecainide SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 22237:[DB00027 DB00534] DB00027|Gramicidin D ABCB1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0055085| transmembrane transport SLC12A1;ABCB1 GO:0006810| transport ABCB1;SLC12A1 22238:[DB00027 DB08299] DB00027|Gramicidin D ABCB1 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways 22239:[DB00027 DB00229] DB00027|Gramicidin D ABCB1 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 22240:[DB00027 DB05210] DB00027|Gramicidin D ABCB1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways 22241:[DB00027 DB01588] DB00027|Gramicidin D ABCB1 DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006810| transport GABRB3;GABRG2;GABRB1;GABRA1;GABRA6;GABRR1;GABRA4;ABCB1;GABRA5;GABRA3;GABRR2;GABRD;GABRB2 GO:0042493| response to drug GABRG3;ABCB1 22242:[DB00027 DB00963] DB00027|Gramicidin D ABCB1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 22243:[DB00027 DB05305] DB00027|Gramicidin D ABCB1 DB05305|Cintredekin Besudotox IL13 common genes common pathways 22244:[DB00027 DB06138] DB00027|Gramicidin D ABCB1 DB06138|IRL-1620 EDNRB common genes common pathways 22245:[DB00027 DB00289] DB00027|Gramicidin D ABCB1 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0006810| transport GRIN2A;GRIN2B;ABCB1;SLC6A2;GRIN2C GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;SLC6A2 GO:0042493| response to drug GRIN2A;SLC6A4;SLC6A3;ABCB1;SLC6A2 22246:[DB00027 DB07963] DB00027|Gramicidin D ABCB1 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways GO:0006810| transport TTR;ABCB1 22247:[DB00027 DB11491] DB00027|Gramicidin D ABCB1 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22248:[DB00027 DB02635] DB00027|Gramicidin D ABCB1 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways 22249:[DB00027 DB06751] DB00027|Gramicidin D ABCB1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0055085| transmembrane transport CACNA1C;ABCB1 22250:[DB00027 DB04926] DB00027|Gramicidin D ABCB1 DB04926|Neramexane GRIN3A common genes common pathways 22251:[DB00027 DB07132] DB00027|Gramicidin D ABCB1 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways 22252:[DB00027 DB01650] DB00027|Gramicidin D ABCB1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 22253:[DB00027 DB01257] DB00027|Gramicidin D ABCB1 DB01257|Eculizumab C5 common genes common pathways 22254:[DB00027 DB00150] DB00027|Gramicidin D ABCB1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10;SLC16A2 GO:0006810| transport ABCB1;SLC16A2 22255:[DB00027 DB02825] DB00027|Gramicidin D ABCB1 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways 22256:[DB00027 DB02854] DB00027|Gramicidin D ABCB1 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways 22257:[DB00027 DB06534] DB00027|Gramicidin D ABCB1 DB06534|Thrombopoietin MPL common genes common pathways 22258:[DB00027 DB05166] DB00027|Gramicidin D ABCB1 DB05166|APD668 GPR119 common genes common pathways 22259:[DB00027 DB11577] DB00027|Gramicidin D ABCB1 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 22260:[DB00027 DB01288] DB00027|Gramicidin D ABCB1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways 22261:[DB00027 DB12077] DB00027|Gramicidin D ABCB1 DB12077|Urelumab TNFRSF9 common genes common pathways 22262:[DB00027 DB06155] DB00027|Gramicidin D ABCB1 DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways 22263:[DB00027 DB06274] DB00027|Gramicidin D ABCB1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways 22264:[DB00027 DB05688] DB00027|Gramicidin D ABCB1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A2;SLC6A4 22265:[DB00027 DB00567] DB00027|Gramicidin D ABCB1 DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A5;SLC47A1 GO:0055085| transmembrane transport SLC15A1;SLC22A6;ABCB1;SLC15A2;SLC22A5;SLC22A8;SLC47A1 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 22266:[DB00027 DB04958] DB00027|Gramicidin D ABCB1 DB04958|Epratuzumab CD22 common genes common pathways 22267:[DB00027 DB04166] DB00027|Gramicidin D ABCB1 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways 22268:[DB00027 DB00047] DB00027|Gramicidin D ABCB1 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways 22269:[DB00027 DB01483] DB00027|Gramicidin D ABCB1 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0006810| transport GABRA1;GRIK2;GABRA6;GABRA4;ABCB1;GABRA5;GABRA3 GO:0055085| transmembrane transport GRIK2;ABCB1 22270:[DB00027 DB12890] DB00027|Gramicidin D ABCB1 DB12890|Dihydrexidine DRD1 common genes common pathways GO:0042493| response to drug DRD1;ABCB1 22271:[DB00027 DB00130] DB00027|Gramicidin D ABCB1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0042493| response to drug PPAT;CTPS1;ABCB1;PFAS GO:0006810| transport ABCB1;SLC7A8 GO:0055085| transmembrane transport SLC38A3;SLC16A10;ABCB1 22272:[DB00027 DB06579] DB00027|Gramicidin D ABCB1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0006810| transport GABRA6;GABRA4;GABRA1;GABRG2;ABCB1;GABRA5;GABRA3 GO:0042493| response to drug GABRG3;ABCB1 22273:[DB00027 DB07427] DB00027|Gramicidin D ABCB1 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 22274:[DB00027 DB00117] DB00027|Gramicidin D ABCB1 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;SLC38A3;ABCB1 22275:[DB00027 DB01551] DB00027|Gramicidin D ABCB1 DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways 22276:[DB00027 DB04472] DB00027|Gramicidin D ABCB1 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways 22277:[DB00027 DB06749] DB00027|Gramicidin D ABCB1 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCB1 22278:[DB00027 DB00978] DB00027|Gramicidin D ABCB1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0042493| response to drug ABCC2;ABCB1;CYP1A2 GO:0055085| transmembrane transport SLC22A5;ABCC2;ABCB1 GO:0006810| transport ABCC2;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCC2;ABCB1 22279:[DB00027 DB06714] DB00027|Gramicidin D ABCB1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways GO:0055085| transmembrane transport SLC18A2;ABCB1 22280:[DB00027 DB05034] DB00027|Gramicidin D ABCB1 DB05034|Ularitide NPR1 common genes common pathways 22281:[DB00027 DB01463] DB00027|Gramicidin D ABCB1 DB01463|Fencamfamine SLC6A3 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A3 GO:0055085| transmembrane transport SLC6A3;ABCB1 22282:[DB00027 DB04602] DB00027|Gramicidin D ABCB1 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 22283:[DB00027 DB01561] DB00027|Gramicidin D ABCB1 DB01561|Androstanedione HSD17B1 common genes common pathways 22284:[DB00027 DB03917] DB00027|Gramicidin D ABCB1 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways 22285:[DB00027 DB05290] DB00027|Gramicidin D ABCB1 DB05290|SPP 301 EDNRA common genes common pathways 22286:[DB00027 DB09142] DB00027|Gramicidin D ABCB1 DB09142|Sincalide SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3 22287:[DB00027 DB06342] DB00027|Gramicidin D ABCB1 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways 22288:[DB00027 DB04299] DB00027|Gramicidin D ABCB1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways 22289:[DB00027 DB00529] DB00027|Gramicidin D ABCB1 DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways GO:0055085| transmembrane transport SLC16A1;ABCB1;SLC22A6 22290:[DB00027 DB03807] DB00027|Gramicidin D ABCB1 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways 22291:[DB00027 DB07194] DB00027|Gramicidin D ABCB1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways 22292:[DB00027 DB09108] DB00027|Gramicidin D ABCB1 DB09108|Simoctocog Alfa VWF common genes common pathways 22293:[DB00027 DB07423] DB00027|Gramicidin D ABCB1 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways GO:0006810| transport ABCB1;AR 22294:[DB00027 DB02323] DB00027|Gramicidin D ABCB1 DB02323|EM-1745 HSD17B1 common genes common pathways 22295:[DB00027 DB00713] DB00027|Gramicidin D ABCB1 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 22296:[DB00027 DB09195] DB00027|Gramicidin D ABCB1 DB09195|Lorpiprazole HTR2A;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;SLC6A4;CYP2D6;CYP3A4;ALB common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0042493| response to drug SLC6A4;HTR2A;ABCB1;ADRA1A;HTR2C 22297:[DB00027 DB02542] DB00027|Gramicidin D ABCB1 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;UBB GO:0055085| transmembrane transport ABCB1;UBB 22298:[DB00027 DB01047] DB00027|Gramicidin D ABCB1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways 22299:[DB00027 DB04464] DB00027|Gramicidin D ABCB1 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0042493| response to drug ABCB1;MT-ND1;B2M GO:0000086| G2/M transition of mitotic cell cycle ABCB1;UBC GO:0055085| transmembrane transport UBC;ABCB1 22300:[DB00027 DB02796] DB00027|Gramicidin D ABCB1 DB02796|9-Deazainosine PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 22301:[DB00027 DB02162] DB00027|Gramicidin D ABCB1 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways 22302:[DB00027 DB08374] DB00027|Gramicidin D ABCB1 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways 22303:[DB00027 DB04260] DB00027|Gramicidin D ABCB1 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1 22304:[DB00027 DB08357] DB00027|Gramicidin D ABCB1 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways 22305:[DB00027 DB00010] DB00027|Gramicidin D ABCB1 DB00010|Sermorelin GHRHR common genes common pathways 22306:[DB00027 DB08904] DB00027|Gramicidin D ABCB1 DB08904|Certolizumab pegol TNF common genes common pathways 22307:[DB00027 DB08900] DB00027|Gramicidin D ABCB1 DB08900|Teduglutide GLP2R common genes common pathways 22308:[DB00027 DB03523] DB00027|Gramicidin D ABCB1 DB03523|Brequinar DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 22309:[DB00027 DB13167] DB00027|Gramicidin D ABCB1 DB13167|Alclofenac PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22310:[DB00027 DB05941] DB00027|Gramicidin D ABCB1 DB05941|Leronlimab CCR5 common genes common pathways 22311:[DB00027 DB00182] DB00027|Gramicidin D ABCB1 DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A3;SLC22A3;SLC18A2;SLC22A5;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 GO:0042493| response to drug ADRA1A;DRD2;ABCB1;SLC6A3;SLC6A2;MAOB;SLC6A4 GO:0006855| drug transmembrane transport SLC22A3;SLC22A5;ABCB1 22312:[DB00027 DB00036] DB00027|Gramicidin D ABCB1 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways 22313:[DB00027 DB07567] DB00027|Gramicidin D ABCB1 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways 22314:[DB00027 DB03660] DB00027|Gramicidin D ABCB1 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways 22315:[DB00027 DB01367] DB00027|Gramicidin D ABCB1 DB01367|Rasagiline MAOB;BCL2;CYP1A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;BCL2 GO:0042493| response to drug ABCB1;MAOB;CYP1A2;BCL2 22316:[DB00027 DB06916] DB00027|Gramicidin D ABCB1 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways 22317:[DB00027 DB12271] DB00027|Gramicidin D ABCB1 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways 22318:[DB00027 DB03060] DB00027|Gramicidin D ABCB1 DB03060|Sri-9662 DHFR common genes common pathways 22319:[DB00027 DB01307] DB00027|Gramicidin D ABCB1 DB01307|Insulin Detemir INSR;ALB common genes common pathways 22320:[DB00027 DB01571] DB00027|Gramicidin D ABCB1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 22321:[DB00027 DB00353] DB00027|Gramicidin D ABCB1 DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;ABCB1;HTR2B 22322:[DB00027 DB01408] DB00027|Gramicidin D ABCB1 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCB1 22323:[DB00027 DB00340] DB00027|Gramicidin D ABCB1 DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways 22324:[DB00027 DB08737] DB00027|Gramicidin D ABCB1 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways 22325:[DB00027 DB04343] DB00027|Gramicidin D ABCB1 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A3 22326:[DB00027 DB04478] DB00027|Gramicidin D ABCB1 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0042493| response to drug SORD;ABCB1 22327:[DB00027 DB00324] DB00027|Gramicidin D ABCB1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways 22328:[DB00027 DB07380] DB00027|Gramicidin D ABCB1 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 22329:[DB00027 DB02067] DB00027|Gramicidin D ABCB1 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways 22330:[DB00027 DB03341] DB00027|Gramicidin D ABCB1 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways 22331:[DB00027 DB04938] DB00027|Gramicidin D ABCB1 DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways 22332:[DB00027 DB05072] DB00027|Gramicidin D ABCB1 DB05072|AV608 TACR1 common genes common pathways 22333:[DB00027 DB02648] DB00027|Gramicidin D ABCB1 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways 22334:[DB00027 DB02583] DB00027|Gramicidin D ABCB1 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways 22335:[DB00027 DB04230] DB00027|Gramicidin D ABCB1 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 22336:[DB00027 DB02078] DB00027|Gramicidin D ABCB1 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways GO:0042493| response to drug ABCB1;FYN 22337:[DB00027 DB13961] DB00027|Gramicidin D ABCB1 DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0042493| response to drug PTGS2;PPARG;SREBF1;ABCB1 GO:0055085| transmembrane transport CACNA1F;ABCB1;CACNA1S;CACNA1C;CACNA1D GO:0006810| transport CACNB4;CACNB1;ABCB1;CACNB3 22338:[DB00027 DB00261] DB00027|Gramicidin D ABCB1 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;PDE3A;CYP1A2 22339:[DB00027 DB01942] DB00027|Gramicidin D ABCB1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0055085| transmembrane transport SLC16A3;ABCB1 22340:[DB00027 DB01098] DB00027|Gramicidin D ABCB1 DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways GO:0042493| response to drug ABCC4;ABCC1;ABCB1;ABCG2;ABCC2 GO:0055085| transmembrane transport ABCC4;SLCO1B3;SLCO1B1;SLC22A8;ABCB11;SLCO1A2;ABCG2;SLCO2B1;ABCC2;ABCB1;ABCC1 GO:0006810| transport ABCC2;ABCG2;ABCB1;ABCC1;ABCB11 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 22341:[DB00027 DB08447] DB00027|Gramicidin D ABCB1 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways 22342:[DB00027 DB08258] DB00027|Gramicidin D ABCB1 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways 22343:[DB00027 DB13508] DB00027|Gramicidin D ABCB1 DB13508|Cloranolol CYP2D6 common genes common pathways 22344:[DB00027 DB01236] DB00027|Gramicidin D ABCB1 DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:0055085| transmembrane transport KCNA1;ABCB1 GO:0006810| transport GABRB3;GABRA6;GABRA4;GABRA1;GABRG2;GABRB1;ABCB1;GABRD;GABRB2;GABRA5;GABRA3 GO:0042493| response to drug GABRG3;CYP2E1;ABCB1;MT-ND1 22345:[DB00027 DB01007] DB00027|Gramicidin D ABCB1 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 22346:[DB00027 DB06711] DB00027|Gramicidin D ABCB1 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 22347:[DB00027 DB00513] DB00027|Gramicidin D ABCB1 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways 22348:[DB00027 DB09481] DB00027|Gramicidin D ABCB1 DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0042493| response to drug ABCB1;GRIN2A GO:0006810| transport GRIN2A;GRIN2B;ABCB1;GRIN2C GO:0055085| transmembrane transport ABCB1;SLC41A3;TRPM7;TRPM6 22349:[DB00027 DB07666] DB00027|Gramicidin D ABCB1 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways 22350:[DB00027 DB04237] DB00027|Gramicidin D ABCB1 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways 22351:[DB00027 DB03115] DB00027|Gramicidin D ABCB1 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways 22352:[DB00027 DB02489] DB00027|Gramicidin D ABCB1 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22353:[DB00027 DB13746] DB00027|Gramicidin D ABCB1 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes common pathways GO:0006810| transport CACNB1;ABCB1;CACNA1I;CACNB3;CACNB4 GO:0055085| transmembrane transport CACNA1H;CACNA1D;CACNA1C;CACNA1G;CACNA1S;CACNA1A;ABCB1;CACNA1I;CACNA1F 22354:[DB00027 DB01410] DB00027|Gramicidin D ABCB1 DB01410|Ciclesonide NR3C1;CYP3A4;CYP2D6;CES1;SERPINA6 common genes common pathways 22355:[DB00027 DB03802] DB00027|Gramicidin D ABCB1 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways 22356:[DB00027 DB04365] DB00027|Gramicidin D ABCB1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways 22357:[DB00027 DB01593] DB00027|Gramicidin D ABCB1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0055085| transmembrane transport ABCB1;APOA1 GO:0042493| response to drug MDM2;TP53;APOA2;HDAC1;HDAC4;ABCB1;TP73;APOA1;SOD1;MGMT;NME1 22358:[DB00027 DB00075] DB00027|Gramicidin D ABCB1 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 22359:[DB00027 DB13893] DB00027|Gramicidin D ABCB1 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways 22360:[DB00027 DB08387] DB00027|Gramicidin D ABCB1 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 22361:[DB00027 DB00607] DB00027|Gramicidin D ABCB1 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 GO:0055085| transmembrane transport SLC22A6;ABCB1 22362:[DB00027 DB05932] DB00027|Gramicidin D ABCB1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways 22363:[DB00027 DB06786] DB00027|Gramicidin D ABCB1 DB06786|Halcinonide SMO;CYP3A4 common genes common pathways 22364:[DB00027 DB00514] DB00027|Gramicidin D ABCB1 DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYBB;SLC6A2;SLC6A4;CYBA;CYP2E1 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCB1 22365:[DB00027 DB01101] DB00027|Gramicidin D ABCB1 DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways GO:0042493| response to drug TYMS;ABCB1 22366:[DB00027 DB13141] DB00027|Gramicidin D ABCB1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 22367:[DB00027 DB05096] DB00027|Gramicidin D ABCB1 DB05096|LY2140023 GRM2;GRM3 common genes common pathways 22368:[DB00027 DB01275] DB00027|Gramicidin D ABCB1 DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways 22369:[DB00027 DB12092] DB00027|Gramicidin D ABCB1 DB12092|Naftopidil CYP3A4 common genes common pathways 22370:[DB00027 DB00134] DB00027|Gramicidin D ABCB1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0042493| response to drug MTHFR;ABCB1 GO:0055085| transmembrane transport SLC16A10;ABCB1 22371:[DB00027 DB05895] DB00027|Gramicidin D ABCB1 DB05895|HGS-TR2J TNFRSF10B common genes common pathways 22372:[DB00027 DB02943] DB00027|Gramicidin D ABCB1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways 22373:[DB00027 DB01327] DB00027|Gramicidin D ABCB1 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1;SLC22A8;ABCC4;SLC22A11 GO:0042493| response to drug ABCB1;ABCC4 22374:[DB00027 DB07280] DB00027|Gramicidin D ABCB1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 22375:[DB00027 DB03182] DB00027|Gramicidin D ABCB1 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 22376:[DB00027 DB02021] DB00027|Gramicidin D ABCB1 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways 22377:[DB00027 DB04616] DB00027|Gramicidin D ABCB1 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways 22378:[DB00027 DB13923] DB00027|Gramicidin D ABCB1 DB13923|Emicizumab F9;F10 common genes common pathways 22379:[DB00027 DB00112] DB00027|Gramicidin D ABCB1 DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 22380:[DB00027 DB05771] DB00027|Gramicidin D ABCB1 DB05771|LLL-3348 IL10 common genes common pathways GO:0042493| response to drug IL10;ABCB1 22381:[DB00027 DB06458] DB00027|Gramicidin D ABCB1 DB06458|Remacemide CYP3A4 common genes common pathways 22382:[DB00027 DB07840] DB00027|Gramicidin D ABCB1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways 22383:[DB00027 DB05235] DB00027|Gramicidin D ABCB1 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0006810| transport TTR;ABCB1 22384:[DB00027 DB01295] DB00027|Gramicidin D ABCB1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 22385:[DB00027 DB08164] DB00027|Gramicidin D ABCB1 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways 22386:[DB00027 DB01336] DB00027|Gramicidin D ABCB1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways 22387:[DB00027 DB06655] DB00027|Gramicidin D ABCB1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways 22388:[DB00027 DB04539] DB00027|Gramicidin D ABCB1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways 22389:[DB00027 DB00559] DB00027|Gramicidin D ABCB1 DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0006810| transport ABCB11;ABCB1 22390:[DB00027 DB00162] DB00027|Gramicidin D ABCB1 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1;APOD 22391:[DB00027 DB00823] DB00027|Gramicidin D ABCB1 DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways 22392:[DB00027 DB05372] DB00027|Gramicidin D ABCB1 DB05372|CP-945598 CNR1 common genes common pathways 22393:[DB00027 DB07908] DB00027|Gramicidin D ABCB1 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways 22394:[DB00027 DB06586] DB00027|Gramicidin D ABCB1 DB06586|Cetilistat PNLIP common genes common pathways 22395:[DB00027 DB00174] DB00027|Gramicidin D ABCB1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;SLC38A3;ABCB1 22396:[DB00027 DB04873] DB00027|Gramicidin D ABCB1 DB04873|Piboserod HTR4 common genes common pathways 22397:[DB00027 DB01154] DB00027|Gramicidin D ABCB1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways GO:0055085| transmembrane transport KCNJ11;ABCB1 GO:0006810| transport ABCB1;GABRA1 GO:0042493| response to drug KCNJ11;CYP2E1;ABCB1 22398:[DB00027 DB07046] DB00027|Gramicidin D ABCB1 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways 22399:[DB00027 DB01356] DB00027|Gramicidin D ABCB1 DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:0006810| transport GRIA3;ABCB1 22400:[DB00027 DB01031] DB00027|Gramicidin D ABCB1 DB01031|Ethinamate CA1;CA2 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 22401:[DB00027 DB06779] DB00027|Gramicidin D ABCB1 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways 22402:[DB00027 DB11937] DB00027|Gramicidin D ABCB1 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways 22403:[DB00027 DB06159] DB00027|Gramicidin D ABCB1 DB06159|Rubitecan TOP1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 22404:[DB00027 DB05501] DB00027|Gramicidin D ABCB1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways 22405:[DB00027 DB03839] DB00027|Gramicidin D ABCB1 DB03839|D-Tyrosine SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 22406:[DB00027 DB06862] DB00027|Gramicidin D ABCB1 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways GO:0042493| response to drug CASP3;ABCB1 22407:[DB00027 DB06492] DB00027|Gramicidin D ABCB1 DB06492|Mirococept C3 common genes common pathways 22408:[DB00027 DB01426] DB00027|Gramicidin D ABCB1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 22409:[DB00027 DB04551] DB00027|Gramicidin D ABCB1 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO2A1 22410:[DB00027 DB12520] DB00027|Gramicidin D ABCB1 DB12520|Plozalizumab CCR2 common genes common pathways 22411:[DB00027 DB07558] DB00027|Gramicidin D ABCB1 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways GO:0055085| transmembrane transport ABCB1;PSMA7 22412:[DB00027 DB08830] DB00027|Gramicidin D ABCB1 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLC2A1;ABCB1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 22413:[DB00027 DB07958] DB00027|Gramicidin D ABCB1 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways 22414:[DB00027 DB00462] DB00027|Gramicidin D ABCB1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways 22415:[DB00027 DB04850] DB00027|Gramicidin D ABCB1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1 22416:[DB00027 DB05142] DB00027|Gramicidin D ABCB1 DB05142|ND7001 PDE2A;PDE2A common genes common pathways 22417:[DB00027 DB06266] DB00027|Gramicidin D ABCB1 DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CFTR 22418:[DB00027 DB04858] DB00027|Gramicidin D ABCB1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 22419:[DB00027 DB03348] DB00027|Gramicidin D ABCB1 DB03348|Huperzine B ACHE common genes common pathways 22420:[DB00027 DB05930] DB00027|Gramicidin D ABCB1 DB05930|SB-559448 MPL common genes common pathways 22421:[DB00027 DB01864] DB00027|Gramicidin D ABCB1 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways 22422:[DB00027 DB05457] DB00027|Gramicidin D ABCB1 DB05457|OSI-7904L TYMS common genes common pathways GO:0042493| response to drug ABCB1;TYMS 22423:[DB00027 DB02032] DB00027|Gramicidin D ABCB1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 22424:[DB00027 DB00668] DB00027|Gramicidin D ABCB1 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0042493| response to drug ABCB1;ADRA1A;COMT;MAOB GO:0006855| drug transmembrane transport SLC22A2;ABCB1;SLC22A1 22425:[DB00027 DB04489] DB00027|Gramicidin D ABCB1 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 22426:[DB00027 DB09295] DB00027|Gramicidin D ABCB1 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 GO:0006810| transport CLCNKA;ABCB1 GO:0055085| transmembrane transport ABCB1;CLCNKA 22427:[DB00027 DB06011] DB00027|Gramicidin D ABCB1 DB06011|AMG-222 DPP4 common genes common pathways 22428:[DB00027 DB00394] DB00027|Gramicidin D ABCB1 DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways 22429:[DB00027 DB00811] DB00027|Gramicidin D ABCB1 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways 22430:[DB00027 DB05395] DB00027|Gramicidin D ABCB1 DB05395|Amibegron ADRB3 common genes common pathways 22431:[DB00027 DB00577] DB00027|Gramicidin D ABCB1 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways GO:0006810| transport SLC15A1;SLC10A2;ABCB1;SLC15A2;SLC6A14 GO:0055085| transmembrane transport SLC22A8;SLC15A2;SLC6A14;SLC15A1;SLC22A6;ABCB1;SLC10A2 22432:[DB00027 DB00699] DB00027|Gramicidin D ABCB1 DB00699|Nicergoline ADRA1A;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 22433:[DB00027 DB01171] DB00027|Gramicidin D ABCB1 DB01171|Moclobemide MAOA;MAOA;MAOB;MAOB;MAOA;MAOB;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;MAOB 22434:[DB00027 DB05678] DB00027|Gramicidin D ABCB1 DB05678|SLx-4090 MTTP common genes common pathways 22435:[DB00027 DB01397] DB00027|Gramicidin D ABCB1 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 22436:[DB00027 DB00532] DB00027|Gramicidin D ABCB1 DB00532|Mephenytoin SCN5A;NR1I2;CYP2C19;CYP2B6;CYP1A2;CYP2D6;CYP2C8;CYP2C9 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0055085| transmembrane transport SCN5A;ABCB1 GO:0042493| response to drug CYP1A2;ABCB1 22437:[DB00027 DB01017] DB00027|Gramicidin D ABCB1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0042493| response to drug CASP3;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A7;SLC22A11;SLC22A8 22438:[DB00027 DB03283] DB00027|Gramicidin D ABCB1 DB03283|beta-L-fucose ACHE common genes common pathways 22439:[DB00027 DB02391] DB00027|Gramicidin D ABCB1 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 22440:[DB00027 DB14498] DB00027|Gramicidin D ABCB1 DB14498|Potassium acetate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 22441:[DB00027 DB05478] DB00027|Gramicidin D ABCB1 DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways 22442:[DB00027 DB00456] DB00027|Gramicidin D ABCB1 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport SLC22A8;SLC22A5;SLC15A2;SLC22A7;SLC22A11;SLC22A6;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 22443:[DB00027 DB03214] DB00027|Gramicidin D ABCB1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways 22444:[DB00027 DB06987] DB00027|Gramicidin D ABCB1 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways 22445:[DB00027 DB11623] DB00027|Gramicidin D ABCB1 DB11623|Candoxatrilat MME common genes common pathways 22446:[DB00027 DB02299] DB00027|Gramicidin D ABCB1 DB02299|Arginineamide KCNA4 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNA4 22447:[DB00027 DB11582] DB00027|Gramicidin D ABCB1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0006810| transport GABRB3;GABRA6;GABRA4;GABRA1;GABRG2;GABRB1;ABCB1;GABRD;GABRB2;GABRA3;GABRA5 GO:0042493| response to drug ABCB1;GABRG3 22448:[DB00027 DB08799] DB00027|Gramicidin D ABCB1 DB08799|Antazoline HRH1 common genes common pathways 22449:[DB00027 DB03934] DB00027|Gramicidin D ABCB1 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways 22450:[DB00027 DB06081] DB00027|Gramicidin D ABCB1 DB06081|Caplacizumab VWF common genes common pathways 22451:[DB00027 DB12637] DB00027|Gramicidin D ABCB1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways 22452:[DB00027 DB07000] DB00027|Gramicidin D ABCB1 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways 22453:[DB00027 DB07070] DB00027|Gramicidin D ABCB1 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways 22454:[DB00027 DB05447] DB00027|Gramicidin D ABCB1 DB05447|AVI-4557 HNF4A common genes common pathways 22455:[DB00027 DB01190] DB00027|Gramicidin D ABCB1 DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways 22456:[DB00027 DB00982] DB00027|Gramicidin D ABCB1 DB00982|Isotretinoin RARA common genes common pathways 22457:[DB00027 DB05107] DB00027|Gramicidin D ABCB1 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways 22458:[DB00027 DB01990] DB00027|Gramicidin D ABCB1 DB01990|Cholesterol sulfate RORA common genes common pathways 22459:[DB00027 DB03682] DB00027|Gramicidin D ABCB1 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 22460:[DB00027 DB02868] DB00027|Gramicidin D ABCB1 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways GO:0055085| transmembrane transport CALM1;ABCB1 22461:[DB00027 DB01328] DB00027|Gramicidin D ABCB1 DB01328|Cefonicid mrcA;ALB common genes common pathways 22462:[DB00027 DB04817] DB00027|Gramicidin D ABCB1 DB04817|Metamizole PTGS1;CYP2B6;CYP3A4 common genes common pathways 22463:[DB00027 DB00202] DB00027|Gramicidin D ABCB1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE 22464:[DB00027 DB13178] DB00027|Gramicidin D ABCB1 DB13178|Inositol SLC5A3 common genes common pathways GO:0006810| transport ABCB1;SLC5A3 GO:0055085| transmembrane transport SLC5A3;ABCB1 22465:[DB00027 DB12670] DB00027|Gramicidin D ABCB1 DB12670|Rolofylline ADORA1 common genes common pathways 22466:[DB00027 DB05243] DB00027|Gramicidin D ABCB1 DB05243|XL019 JAK2 common genes common pathways 22467:[DB00027 DB11692] DB00027|Gramicidin D ABCB1 DB11692|Pavinetant TACR3 common genes common pathways 22468:[DB00027 DB07157] DB00027|Gramicidin D ABCB1 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways 22469:[DB00027 DB06282] DB00027|Gramicidin D ABCB1 DB06282|Levocetirizine HRH1 common genes common pathways 22470:[DB00027 DB01404] DB00027|Gramicidin D ABCB1 DB01404|Ginseng IL6;PTGS2;AHR common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22471:[DB00027 DB08006] DB00027|Gramicidin D ABCB1 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 22472:[DB00027 DB06735] DB00027|Gramicidin D ABCB1 DB06735|Enclomiphene CYP2D6 common genes common pathways 22473:[DB00027 DB01364] DB00027|Gramicidin D ABCB1 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC18A2;SLC6A2;ABCB1 GO:0042493| response to drug ADRA1A;ABCB1;SLC6A2;BCHE 22474:[DB00027 DB06697] DB00027|Gramicidin D ABCB1 DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways 22475:[DB00027 DB04682] DB00027|Gramicidin D ABCB1 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 22476:[DB00027 DB06997] DB00027|Gramicidin D ABCB1 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways 22477:[DB00027 DB05464] DB00027|Gramicidin D ABCB1 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways 22478:[DB00027 DB04381] DB00027|Gramicidin D ABCB1 DB04381|Crotonaldehyde ALDH2 common genes common pathways 22479:[DB00027 DB01095] DB00027|Gramicidin D ABCB1 DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0042493| response to drug UGT1A1;CYP1A1;ABCB1;ABCC2 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO2B1;ABCC2;SLCO1B3;SLCO1B1 GO:0006810| transport SLC15A1;ABCC2;ABCB1 22480:[DB00027 DB01644] DB00027|Gramicidin D ABCB1 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways 22481:[DB00027 DB03991] DB00027|Gramicidin D ABCB1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways 22482:[DB00027 DB08350] DB00027|Gramicidin D ABCB1 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways 22483:[DB00027 DB08743] DB00027|Gramicidin D ABCB1 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways 22484:[DB00027 DB05200] DB00027|Gramicidin D ABCB1 DB05200|AT2220 GAA common genes common pathways 22485:[DB00027 DB01472] DB00027|Gramicidin D ABCB1 DB01472|4-Methoxyamphetamine SLC6A3;SLC6A4;SLC18A2;ADRA1A;ADRA2A;MAOA;MAOB;CYP2D6 common genes common pathways GO:0042493| response to drug SLC6A4;MAOB;SLC6A3;ADRA1A;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A4;SLC18A2 22486:[DB00027 DB14707] DB00027|Gramicidin D ABCB1 DB14707|Cemiplimab PDCD1 common genes common pathways 22487:[DB00027 DB12960] DB00027|Gramicidin D ABCB1 DB12960|INCB-9471 CCR5 common genes common pathways 22488:[DB00027 DB04953] DB00027|Gramicidin D ABCB1 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways GO:0055085| transmembrane transport KCNQ4;ABCB1;KCNQ3;KCNQ2;KCNQ5 GO:0042493| response to drug UGT1A1;ABCB1 22489:[DB00027 DB09333] DB00027|Gramicidin D ABCB1 DB09333|Iopodic acid DIO3;ALB common genes common pathways 22490:[DB00027 DB06707] DB00027|Gramicidin D ABCB1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways 22491:[DB00027 DB09143] DB00027|Gramicidin D ABCB1 DB09143|Sonidegib SMO;CYP3A4 common genes common pathways 22492:[DB00027 DB00293] DB00027|Gramicidin D ABCB1 DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0042493| response to drug TYMS;ABCB1 22493:[DB00027 DB07602] DB00027|Gramicidin D ABCB1 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways 22494:[DB00027 DB07609] DB00027|Gramicidin D ABCB1 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways 22495:[DB00027 DB00835] DB00027|Gramicidin D ABCB1 DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 22496:[DB00027 DB04617] DB00027|Gramicidin D ABCB1 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways 22497:[DB00027 DB00576] DB00027|Gramicidin D ABCB1 DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways 22498:[DB00027 DB01213] DB00027|Gramicidin D ABCB1 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0042493| response to drug CAT;CYP2E1;ABCB1 22499:[DB00027 DB00718] DB00027|Gramicidin D ABCB1 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0006810| transport ABCC5;ABCB1 GO:0055085| transmembrane transport SLC22A3;ABCC4;SLC22A6;ABCC5;ABCB1 GO:0042493| response to drug ABCB1;ABCC4;NME1;AK4 GO:0006855| drug transmembrane transport SLC22A3;ABCB1 22500:[DB00027 DB00368] DB00027|Gramicidin D ABCB1 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;SLC18A1;SLC22A3;SLC22A2;ABCB1;SLC22A1 GO:0055085| transmembrane transport SLC22A1;SLC6A2;ABCB1;SLC22A2;SLC18A1;SLC22A3;SLC18A2;SLC22A5 GO:0006810| transport ABCB1;SLC6A2 GO:0042493| response to drug ABCB1;ADRA1A;SLC6A2 22501:[DB00027 DB08238] DB00027|Gramicidin D ABCB1 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways 22502:[DB00027 DB00151] DB00027|Gramicidin D ABCB1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:0042493| response to drug GCLM;ABCB1;MGMT 22503:[DB00027 DB02751] DB00027|Gramicidin D ABCB1 DB02751|Glycocyamine GAMT common genes common pathways 22504:[DB00027 DB03185] DB00027|Gramicidin D ABCB1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 22505:[DB00027 DB03453] DB00027|Gramicidin D ABCB1 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways 22506:[DB00027 DB09292] DB00027|Gramicidin D ABCB1 DB09292|Sacubitril MME;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 22507:[DB00027 DB08024] DB00027|Gramicidin D ABCB1 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways 22508:[DB00027 DB09038] DB00027|Gramicidin D ABCB1 DB09038|Empagliflozin SLC5A2 common genes common pathways GO:0055085| transmembrane transport SLC5A2;ABCB1 GO:0006810| transport ABCB1;SLC5A2 22509:[DB00027 DB07586] DB00027|Gramicidin D ABCB1 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways 22510:[DB00027 DB00074] DB00027|Gramicidin D ABCB1 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways 22511:[DB00027 DB00755] DB00027|Gramicidin D ABCB1 DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1 22512:[DB00027 DB03516] DB00027|Gramicidin D ABCB1 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways 22513:[DB00027 DB00749] DB00027|Gramicidin D ABCB1 DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 GO:0055085| transmembrane transport SLC22A6;ABCB1 22514:[DB00027 DB03128] DB00027|Gramicidin D ABCB1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A5 GO:0006855| drug transmembrane transport SLC22A5;ABCB1;SLC22A1 22515:[DB00027 DB01306] DB00027|Gramicidin D ABCB1 DB01306|Insulin Aspart INSR common genes common pathways 22516:[DB00027 DB14570] DB00027|Gramicidin D ABCB1 DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways 22517:[DB00027 DB02198] DB00027|Gramicidin D ABCB1 DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways 22518:[DB00027 DB00148] DB00027|Gramicidin D ABCB1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006810| transport SLC6A8;ABCB1 GO:0055085| transmembrane transport SLC22A5;SLC6A8;ABCB1 22519:[DB00027 DB07780] DB00027|Gramicidin D ABCB1 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways 22520:[DB00027 DB06090] DB00027|Gramicidin D ABCB1 DB06090|Bradanicline CHRNA7 common genes common pathways 22521:[DB00027 DB01614] DB00027|Gramicidin D ABCB1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0042493| response to drug HTR2A;DRD1;ABCB1;ADRA1A;DRD2 22522:[DB00027 DB13151] DB00027|Gramicidin D ABCB1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways 22523:[DB00027 DB00475] DB00027|Gramicidin D ABCB1 DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;GABRG3 GO:0006810| transport ABCB1;GABRA5;GABRA3;GABRD;GABRB2;GABRB3;GABRG2;GABRB1;GABRA6;GABRA4;GABRA1 22524:[DB00027 DB01431] DB00027|Gramicidin D ABCB1 DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways 22525:[DB00027 DB01610] DB00027|Gramicidin D ABCB1 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2;SLC6A14 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC15A2;SLC6A14 22526:[DB00027 DB11914] DB00027|Gramicidin D ABCB1 DB11914|Lebrikizumab IL13;IL13 common genes common pathways 22527:[DB00027 DB01382] DB00027|Gramicidin D ABCB1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0042493| response to drug ABCC8;ABCB1 GO:0055085| transmembrane transport ABCC8;ABCB1 22528:[DB00027 DB08836] DB00027|Gramicidin D ABCB1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0055085| transmembrane transport SLC15A1;ABCB1;SLCO1A2 GO:0006810| transport SLC15A1;ABCB1 22529:[DB00027 DB00165] DB00027|Gramicidin D ABCB1 DB00165|Pyridoxine PDXK;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1 22530:[DB00027 DB00714] DB00027|Gramicidin D ABCB1 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0042493| response to drug HTR2C;HTR2B;DRD2;HTR1B;ABCB1;DRD3;DRD1;HTR2A 22531:[DB00027 DB01600] DB00027|Gramicidin D ABCB1 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22532:[DB00027 DB06843] DB00027|Gramicidin D ABCB1 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug ABCB1;GNAS 22533:[DB00027 DB08675] DB00027|Gramicidin D ABCB1 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways 22534:[DB00027 DB00039] DB00027|Gramicidin D ABCB1 DB00039|Palifermin FGFR2;NRP1;FGFR1;FGFR4;FGFR3;HSPG2 common genes common pathways 22535:[DB00027 DB06699] DB00027|Gramicidin D ABCB1 DB06699|Degarelix GNRHR common genes common pathways 22536:[DB00027 DB05687] DB00027|Gramicidin D ABCB1 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0042493| response to drug HTR2A;DRD2;ABCB1 22537:[DB00027 DB04972] DB00027|Gramicidin D ABCB1 DB04972|Canfosfamide GSTP1 common genes common pathways 22538:[DB00027 DB06822] DB00027|Gramicidin D ABCB1 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways 22539:[DB00027 DB00200] DB00027|Gramicidin D ABCB1 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways 22540:[DB00027 DB09564] DB00027|Gramicidin D ABCB1 DB09564|Insulin Degludec INSR common genes common pathways 22541:[DB00027 DB14517] DB00027|Gramicidin D ABCB1 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 22542:[DB00027 DB11921] DB00027|Gramicidin D ABCB1 DB11921|Deflazacort CYP3A4 common genes common pathways 22543:[DB00027 DB06931] DB00027|Gramicidin D ABCB1 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 22544:[DB00027 DB01289] DB00027|Gramicidin D ABCB1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways 22545:[DB00027 DB00357] DB00027|Gramicidin D ABCB1 DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways 22546:[DB00027 DB13144] DB00027|Gramicidin D ABCB1 DB13144|Lenograstim CSF3R common genes common pathways 22547:[DB00027 DB08104] DB00027|Gramicidin D ABCB1 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 22548:[DB00027 DB00884] DB00027|Gramicidin D ABCB1 DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 22549:[DB00027 DB01014] DB00027|Gramicidin D ABCB1 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;PPARG 22550:[DB00027 DB04334] DB00027|Gramicidin D ABCB1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways 22551:[DB00027 DB14041] DB00027|Gramicidin D ABCB1 DB14041|Fremanezumab CALCA;CALCB common genes common pathways 22552:[DB00027 DB05265] DB00027|Gramicidin D ABCB1 DB05265|Ecabet NOXO1;ureC common genes common pathways 22553:[DB00027 DB09309] DB00027|Gramicidin D ABCB1 DB09309|Kitasamycin CYP3A4 common genes common pathways 22554:[DB00027 DB05479] DB00027|Gramicidin D ABCB1 DB05479|CZEN 002 MC1R common genes common pathways 22555:[DB00027 DB00993] DB00027|Gramicidin D ABCB1 DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22556:[DB00027 DB01056] DB00027|Gramicidin D ABCB1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 GO:0055085| transmembrane transport ABCB1;SCN5A 22557:[DB00027 DB04876] DB00027|Gramicidin D ABCB1 DB04876|Vildagliptin DPP4 common genes common pathways 22558:[DB00027 DB08057] DB00027|Gramicidin D ABCB1 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways GO:0042493| response to drug ABCB1;LCK 22559:[DB00027 DB00976] DB00027|Gramicidin D ABCB1 DB00976|Telithromycin CYP3A7;CYP3A4;CYP3A5;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1;SLCO1B3 22560:[DB00027 DB11077] DB00027|Gramicidin D ABCB1 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways 22561:[DB00027 DB11487] DB00027|Gramicidin D ABCB1 DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways 22562:[DB00027 DB11093] DB00027|Gramicidin D ABCB1 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0042493| response to drug ABCB1;CALR;SLC8A1 GO:0055085| transmembrane transport CACNA1I;ABCB1;CACNA1A;CACNA1F;RYR2;CATSPER1;CACNA1S;TRPV5;CACNA1G;CACNA1E;RYR3;TRPV6;CACNA1D;SLC8A1;CACNA1C;RYR1;CALM1;CACNA1H GO:0006810| transport CACNA1I;ABCB1;CACNB1;CACNA1E;CACNB3;CACNB4;SRI 22563:[DB00027 DB04896] DB00027|Gramicidin D ABCB1 DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;SLC6A4;GRIN2A GO:0006810| transport SLC6A2;GRIN2C;ABCB1;GRIN2B;GRIN2A GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCB1 22564:[DB00027 DB08358] DB00027|Gramicidin D ABCB1 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 22565:[DB00027 DB01354] DB00027|Gramicidin D ABCB1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport GRIK2;GABRA6;GABRA4;GABRA1;ABCB1;GABRA3;GABRA5 22566:[DB00027 DB11948] DB00027|Gramicidin D ABCB1 DB11948|Lapachone RBP3 common genes common pathways 22567:[DB00027 DB01255] DB00027|Gramicidin D ABCB1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0006810| transport ABCB1;SLC15A1 GO:0055085| transmembrane transport ABCB1;SLC15A1 22568:[DB00027 DB04327] DB00027|Gramicidin D ABCB1 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0042493| response to drug ABCB1;PTEN 22569:[DB00027 DB08688] DB00027|Gramicidin D ABCB1 DB08688|undecan-2-one ACOT13 common genes common pathways 22570:[DB00027 DB06880] DB00027|Gramicidin D ABCB1 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways 22571:[DB00027 DB04263] DB00027|Gramicidin D ABCB1 DB04263|Geneticin ODC1 common genes common pathways 22572:[DB00027 DB00007] DB00027|Gramicidin D ABCB1 DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways 22573:[DB00027 DB08693] DB00027|Gramicidin D ABCB1 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 22574:[DB00027 DB00127] DB00027|Gramicidin D ABCB1 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A4;SLC22A1;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 22575:[DB00027 DB09238] DB00027|Gramicidin D ABCB1 DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 GO:0006810| transport CACNB1;CACNA1I;ABCB1;CACNB3;CACNB4 GO:0055085| transmembrane transport CACNA1H;CACNA1C;CACNA1D;CACNA1G;CACNA1S;CACNA1F;CACNA1I;ABCB1 22576:[DB00027 DB07382] DB00027|Gramicidin D ABCB1 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways 22577:[DB00027 DB01712] DB00027|Gramicidin D ABCB1 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways 22578:[DB00027 DB00301] DB00027|Gramicidin D ABCB1 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways GO:0006810| transport ABCB1;ABCB11 GO:0055085| transmembrane transport ABCB11;ABCB1 22579:[DB00027 DB00547] DB00027|Gramicidin D ABCB1 DB00547|Desoximetasone NR3C1 common genes common pathways 22580:[DB00027 DB04835] DB00027|Gramicidin D ABCB1 DB04835|Maraviroc CCR5;CYP3A4 common genes common pathways 22581:[DB00027 DB00868] DB00027|Gramicidin D ABCB1 DB00868|Benzonatate SCN5A common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCB1 22582:[DB00027 DB07795] DB00027|Gramicidin D ABCB1 DB07795|Fisetin CDK6 common genes common pathways 22583:[DB00027 DB09103] DB00027|Gramicidin D ABCB1 DB09103|Ancestim KIT common genes common pathways 22584:[DB00027 DB12731] DB00027|Gramicidin D ABCB1 DB12731|Daporinad NAMPT common genes common pathways 22585:[DB00027 DB07201] DB00027|Gramicidin D ABCB1 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 22586:[DB00027 DB05077] DB00027|Gramicidin D ABCB1 DB05077|SLV319 CNR1 common genes common pathways 22587:[DB00027 DB05446] DB00027|Gramicidin D ABCB1 DB05446|LJP 1082 APOH common genes common pathways 22588:[DB00027 DB06963] DB00027|Gramicidin D ABCB1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 22589:[DB00027 DB00893] DB00027|Gramicidin D ABCB1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways 22590:[DB00027 DB00128] DB00027|Gramicidin D ABCB1 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC25A12;SLC16A10;SLC25A13;ABCB1 22591:[DB00027 DB06321] DB00027|Gramicidin D ABCB1 DB06321|R-348 JAK3 common genes common pathways 22592:[DB00027 DB02281] DB00027|Gramicidin D ABCB1 DB02281|Formycin MTAP common genes common pathways 22593:[DB00027 DB02598] DB00027|Gramicidin D ABCB1 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0042493| response to drug PAM;ABCB1 22594:[DB00027 DB05209] DB00027|Gramicidin D ABCB1 DB05209|SYM001 RHD common genes common pathways 22595:[DB00027 DB14639] DB00027|Gramicidin D ABCB1 DB14639|Boldenone undecylenate AR common genes common pathways GO:0006810| transport ABCB1;AR 22596:[DB00027 DB00757] DB00027|Gramicidin D ABCB1 DB00757|Dolasetron HTR3A;CYP3A4;CYP2D6;CYP2C9 common genes common pathways 22597:[DB00027 DB06802] DB00027|Gramicidin D ABCB1 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 22598:[DB00027 DB01764] DB00027|Gramicidin D ABCB1 DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways 22599:[DB00027 DB06144] DB00027|Gramicidin D ABCB1 DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2C;ABCB1;DRD2;ADRA1A;HTR2A GO:0055085| transmembrane transport KCNH2;ABCB1 22600:[DB00027 DB00797] DB00027|Gramicidin D ABCB1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 22601:[DB00027 DB00345] DB00027|Gramicidin D ABCB1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2;SLC22A2;ABCC1;SLC22A5 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC2;ABCC1 GO:0055085| transmembrane transport SLC16A1;SLC22A7;SLC22A11;SLC22A8;SLC22A5;SLCO1B1;SLC22A4;SLCO1A2;SLCO3A1;SLC22A2;ABCC2;ABCB1;SLC22A6;ABCC1 GO:0006810| transport ABCC2;ABCB1;ABCC1 22602:[DB00027 DB02783] DB00027|Gramicidin D ABCB1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 22603:[DB00027 DB06444] DB00027|Gramicidin D ABCB1 DB06444|Dexanabinol TNF common genes common pathways 22604:[DB00027 DB05595] DB00027|Gramicidin D ABCB1 DB05595|Farletuzumab FOLR1 common genes common pathways 22605:[DB00027 DB00061] DB00027|Gramicidin D ABCB1 DB00061|Pegademase bovine GRB2 common genes common pathways 22606:[DB00027 DB07002] DB00027|Gramicidin D ABCB1 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways 22607:[DB00027 DB01113] DB00027|Gramicidin D ABCB1 DB01113|Papaverine PDE4B;PDE10A common genes common pathways 22608:[DB00027 DB07364] DB00027|Gramicidin D ABCB1 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways 22609:[DB00027 DB05758] DB00027|Gramicidin D ABCB1 DB05758|CYT007-TNFQb TNF common genes common pathways 22610:[DB00027 DB07081] DB00027|Gramicidin D ABCB1 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways 22611:[DB00027 DB06495] DB00027|Gramicidin D ABCB1 DB06495|Onercept TNF common genes common pathways 22612:[DB00027 DB01897] DB00027|Gramicidin D ABCB1 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways 22613:[DB00027 DB01621] DB00027|Gramicidin D ABCB1 DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;ABCB1 GO:0042493| response to drug DRD2;ABCB1;DRD1;HTR2A GO:0006855| drug transmembrane transport SLC22A1;ABCB1 22614:[DB00027 DB11471] DB00027|Gramicidin D ABCB1 DB11471|Tilmicosin CYP3A4 common genes common pathways 22615:[DB00027 DB04844] DB00027|Gramicidin D ABCB1 DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0042493| response to drug DRD2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC18A2 22616:[DB00027 DB08067] DB00027|Gramicidin D ABCB1 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways 22617:[DB00027 DB00425] DB00027|Gramicidin D ABCB1 DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0006810| transport GABRA3;ABCB1;GABRG2;GABRA1;GABRB3 GO:0042493| response to drug ABCB1;CYP1A2 22618:[DB00027 DB11278] DB00027|Gramicidin D ABCB1 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 22619:[DB00027 DB02342] DB00027|Gramicidin D ABCB1 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0042493| response to drug CYP1A1;COMT;ABCB1 22620:[DB00027 DB14502] DB00027|Gramicidin D ABCB1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0042493| response to drug ABCB1;SLC34A1 GO:0006810| transport SLC20A2;SLC20A1;ABCB1 GO:0055085| transmembrane transport SLC20A1;SLC20A2;SLC34A3;SLC34A2;ABCB1 22621:[DB00027 DB02417] DB00027|Gramicidin D ABCB1 DB02417|2,4,6-Tribromophenol TTR common genes common pathways GO:0006810| transport TTR;ABCB1 22622:[DB00027 DB09036] DB00027|Gramicidin D ABCB1 DB09036|Siltuximab IL6;CYP3A4 common genes common pathways 22623:[DB00027 DB07410] DB00027|Gramicidin D ABCB1 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways 22624:[DB00027 DB03542] DB00027|Gramicidin D ABCB1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 22625:[DB00027 DB06510] DB00027|Gramicidin D ABCB1 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0042493| response to drug ABCB1;PPARG;UGT1A1;CYP1A2 22626:[DB00027 DB07776] DB00027|Gramicidin D ABCB1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways 22627:[DB00027 DB06689] DB00027|Gramicidin D ABCB1 DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 22628:[DB00027 DB00922] DB00027|Gramicidin D ABCB1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNJ11 GO:0042493| response to drug ABCB1;PDE3A;KCNJ11 22629:[DB00027 DB01176] DB00027|Gramicidin D ABCB1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways 22630:[DB00027 DB00962] DB00027|Gramicidin D ABCB1 DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0006810| transport ABCB1;GABRA1 GO:0042493| response to drug TSPO;ABCB1 22631:[DB00027 DB09328] DB00027|Gramicidin D ABCB1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1;CYP1A2 22632:[DB00027 DB03597] DB00027|Gramicidin D ABCB1 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways 22633:[DB00027 DB04857] DB00027|Gramicidin D ABCB1 DB04857|Brasofensine DRD2 common genes common pathways GO:0042493| response to drug ABCB1;DRD2 22634:[DB00027 DB02661] DB00027|Gramicidin D ABCB1 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways 22635:[DB00027 DB08229] DB00027|Gramicidin D ABCB1 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways GO:0042493| response to drug ABCB1;CASP3 22636:[DB00027 DB02079] DB00027|Gramicidin D ABCB1 DB02079|Aminooxyacetic acid AGXT common genes common pathways 22637:[DB00027 DB05524] DB00027|Gramicidin D ABCB1 DB05524|Pelitinib EGFR common genes common pathways 22638:[DB00027 DB00784] DB00027|Gramicidin D ABCB1 DB00784|Mefenamic acid PTGS2;PTGS1;CYP2C9;CYP2C8;UGT1A9;ALB common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22639:[DB00027 DB11155] DB00027|Gramicidin D ABCB1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1 22640:[DB00027 DB00348] DB00027|Gramicidin D ABCB1 DB00348|Nitisinone HPD common genes common pathways 22641:[DB00027 DB11644] DB00027|Gramicidin D ABCB1 DB11644|Tafamidis TTR common genes common pathways GO:0006810| transport TTR;ABCB1 22642:[DB00027 DB11751] DB00027|Gramicidin D ABCB1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 22643:[DB00027 DB02076] DB00027|Gramicidin D ABCB1 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways 22644:[DB00027 DB08373] DB00027|Gramicidin D ABCB1 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways GO:0042493| response to drug SCGB1A1;ABCB1 22645:[DB00027 DB04911] DB00027|Gramicidin D ABCB1 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways 22646:[DB00027 DB01048] DB00027|Gramicidin D ABCB1 DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 22647:[DB00027 DB06475] DB00027|Gramicidin D ABCB1 DB06475|Ruplizumab CD40LG common genes common pathways 22648:[DB00027 DB11090] DB00027|Gramicidin D ABCB1 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 22649:[DB00027 DB01097] DB00027|Gramicidin D ABCB1 DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0042493| response to drug CYP1A2;DHODH;ABCB1;PTK2B;ABCG2 22650:[DB00027 DB00670] DB00027|Gramicidin D ABCB1 DB00670|Pirenzepine CHRM1 common genes common pathways 22651:[DB00027 DB04878] DB00027|Gramicidin D ABCB1 DB04878|Voglibose MGAM common genes common pathways 22652:[DB00027 DB00113] DB00027|Gramicidin D ABCB1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways 22653:[DB00027 DB11132] DB00027|Gramicidin D ABCB1 DB11132|Silicon dioxide MARCO common genes common pathways 22654:[DB00027 DB00311] DB00027|Gramicidin D ABCB1 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:2001225| regulation of chloride transport CA2;ABCB1;CA7 22655:[DB00027 DB00308] DB00027|Gramicidin D ABCB1 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0006810| transport CACNG1;CACNB1;ABCB1 GO:0055085| transmembrane transport CACNA1C;KCNJ11;KCNH2;ABCB1;KCNH6;KCNH7 GO:0042493| response to drug KCNJ11;ABCB1 22656:[DB00027 DB09225] DB00027|Gramicidin D ABCB1 DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug DRD1;SLC6A4;HTR2A;CYP1A2;ABCB1;DRD2;SLC6A2 22657:[DB00027 DB09237] DB00027|Gramicidin D ABCB1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0055085| transmembrane transport CACNA1C;ABCB1 22658:[DB00027 DB04368] DB00027|Gramicidin D ABCB1 DB04368|Bb-3497 def;PDF common genes common pathways 22659:[DB00027 DB04214] DB00027|Gramicidin D ABCB1 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 22660:[DB00027 DB05382] DB00027|Gramicidin D ABCB1 DB05382|Iodine MT-ND5 common genes common pathways 22661:[DB00027 DB06762] DB00027|Gramicidin D ABCB1 DB06762|Pinacidil CYP3A4 common genes common pathways 22662:[DB00027 DB02490] DB00027|Gramicidin D ABCB1 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 22663:[DB00027 DB02106] DB00027|Gramicidin D ABCB1 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways 22664:[DB00027 DB00463] DB00027|Gramicidin D ABCB1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug ABCB1;GABRG3 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006810| transport GABRB2;GABRD;GABRA3;GABRA5;ABCB1;GABRA4;GRIK2;GABRA6;GABRA1;GABRB1;GABRG2;GABRB3 22665:[DB00027 DB00680] DB00027|Gramicidin D ABCB1 DB00680|Moricizine SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 22666:[DB00027 DB08035] DB00027|Gramicidin D ABCB1 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways GO:0006810| transport AR;ABCB1 22667:[DB00027 DB03338] DB00027|Gramicidin D ABCB1 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways 22668:[DB00027 DB00579] DB00027|Gramicidin D ABCB1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A3;ABCB1;SLC6A2;SLC6A4;SLC18A2 GO:0042493| response to drug SLC6A3;ABCB1;SLC6A2;SLC6A4 22669:[DB00027 DB07354] DB00027|Gramicidin D ABCB1 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 22670:[DB00027 DB04895] DB00027|Gramicidin D ABCB1 DB04895|Pegaptanib NRP1 common genes common pathways 22671:[DB00027 DB14581] DB00027|Gramicidin D ABCB1 DB14581|CPI-1205 EZH2 common genes common pathways 22672:[DB00027 DB14499] DB00027|Gramicidin D ABCB1 DB14499|Potassium sulfate ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1 22673:[DB00027 DB14538] DB00027|Gramicidin D ABCB1 DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1;SLC22A8;SLCO1A2 GO:0006810| transport ABCG2;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ANXA1;ABCG2;HSD11B2;ABCB1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 22674:[DB00027 DB04661] DB00027|Gramicidin D ABCB1 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways 22675:[DB00027 DB06283] DB00027|Gramicidin D ABCB1 DB06283|Ziconotide CYP3A4 common genes common pathways 22676:[DB00027 DB02343] DB00027|Gramicidin D ABCB1 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways 22677:[DB00027 DB08819] DB00027|Gramicidin D ABCB1 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22678:[DB00027 DB01384] DB00027|Gramicidin D ABCB1 DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways 22679:[DB00027 DB06712] DB00027|Gramicidin D ABCB1 DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CACNA1S;CACNA1D;CACNA1C GO:0042493| response to drug CYP2E1;ABCB1 22680:[DB00027 DB00627] DB00027|Gramicidin D ABCB1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC22A5;SLC16A1;SLC16A3;SLCO2B1;SLC5A8;ABCB1 GO:0042493| response to drug ABCB1;NNMT GO:0006855| drug transmembrane transport ABCB1;SLC22A5 22681:[DB00027 DB00050] DB00027|Gramicidin D ABCB1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways 22682:[DB00027 DB06732] DB00027|Gramicidin D ABCB1 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22683:[DB00027 DB00341] DB00027|Gramicidin D ABCB1 DB00341|Cetirizine HRH1 common genes common pathways 22684:[DB00027 DB05983] DB00027|Gramicidin D ABCB1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways 22685:[DB00027 DB09336] DB00027|Gramicidin D ABCB1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways 22686:[DB00027 DB09532] DB00027|Gramicidin D ABCB1 DB09532|Secretin human SCTR common genes common pathways 22687:[DB00027 DB04100] DB00027|Gramicidin D ABCB1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0042493| response to drug ABCC2;ABCB1 GO:0006810| transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2 22688:[DB00027 DB03041] DB00027|Gramicidin D ABCB1 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 22689:[DB00027 DB01274] DB00027|Gramicidin D ABCB1 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways 22690:[DB00027 DB03442] DB00027|Gramicidin D ABCB1 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways 22691:[DB00027 DB09413] DB00027|Gramicidin D ABCB1 DB09413|Monopotassium phosphate ALPI common genes common pathways 22692:[DB00027 DB06360] DB00027|Gramicidin D ABCB1 DB06360|Lucatumumab CD40 common genes common pathways 22693:[DB00027 DB00035] DB00027|Gramicidin D ABCB1 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22694:[DB00027 DB02745] DB00027|Gramicidin D ABCB1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 22695:[DB00027 DB09217] DB00027|Gramicidin D ABCB1 DB09217|Firocoxib PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22696:[DB00027 DB00430] DB00027|Gramicidin D ABCB1 DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways 22697:[DB00027 DB05017] DB00027|Gramicidin D ABCB1 DB05017|YSIL6 TNF;IL6 common genes common pathways 22698:[DB00027 DB03506] DB00027|Gramicidin D ABCB1 DB03506|9-Deazaadenine APRT common genes common pathways 22699:[DB00027 DB03455] DB00027|Gramicidin D ABCB1 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways 22700:[DB00027 DB12119] DB00027|Gramicidin D ABCB1 DB12119|Gevokizumab IL1B common genes common pathways 22701:[DB00027 DB07617] DB00027|Gramicidin D ABCB1 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways 22702:[DB00027 DB00081] DB00027|Gramicidin D ABCB1 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 22703:[DB00027 DB02587] DB00027|Gramicidin D ABCB1 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1;GNAS GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;CFTR GO:0006810| transport ABCB1 22704:[DB00027 DB08049] DB00027|Gramicidin D ABCB1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0042493| response to drug COMT;ABCB1 22705:[DB00027 DB11198] DB00027|Gramicidin D ABCB1 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22706:[DB00027 DB03040] DB00027|Gramicidin D ABCB1 DB03040|Nitrilotriacetic Acid LTF common genes common pathways 22707:[DB00027 DB00545] DB00027|Gramicidin D ABCB1 DB00545|Pyridostigmine ACHE;BCHE;ALB;CYP3A4 common genes common pathways GO:0042493| response to drug BCHE;ABCB1 22708:[DB00027 DB01330] DB00027|Gramicidin D ABCB1 DB01330|Cefotetan ALB common genes common pathways 22709:[DB00027 DB06549] DB00027|Gramicidin D ABCB1 DB06549|Labradimil BDKRB2 common genes common pathways 22710:[DB00027 DB12474] DB00027|Gramicidin D ABCB1 DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways 22711:[DB00027 DB01043] DB00027|Gramicidin D ABCB1 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0055085| transmembrane transport SLC22A2;ABCB1 GO:0006810| transport ABCB1;GRIN2A;GRIN2B GO:0042493| response to drug DRD2;ABCB1;GRIN2A GO:0006855| drug transmembrane transport ABCB1;SLC22A2 22712:[DB00027 DB09472] DB00027|Gramicidin D ABCB1 DB09472|Sodium sulfate CA2;CA1 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 22713:[DB00027 DB09194] DB00027|Gramicidin D ABCB1 DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A3;ABCB1;SLC6A2;SLC6A4 GO:0042493| response to drug SLC6A2;ABCB1;ADRA1A;DRD2;SLC6A3;HTR2C;HTR2A;SLC6A4 22714:[DB00027 DB00968] DB00027|Gramicidin D ABCB1 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1 GO:0006810| transport SLC15A1;ABCB1 GO:0042493| response to drug COMT;ABCB1 22715:[DB00027 DB00910] DB00027|Gramicidin D ABCB1 DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways 22716:[DB00027 DB02405] DB00027|Gramicidin D ABCB1 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways 22717:[DB00027 DB08952] DB00027|Gramicidin D ABCB1 DB08952|Indenolol CYP2D6 common genes common pathways 22718:[DB00027 DB09035] DB00027|Gramicidin D ABCB1 DB09035|Nivolumab PDCD1 common genes common pathways 22719:[DB00027 DB12159] DB00027|Gramicidin D ABCB1 DB12159|Dupilumab IL4R common genes common pathways 22720:[DB00027 DB08770] DB00027|Gramicidin D ABCB1 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;ABCB1 22721:[DB00027 DB01107] DB00027|Gramicidin D ABCB1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;ABCB1 GO:0006810| transport GABRD;GABRB2;GABRA3;GABRA5;ABCB1;GABRA4;GABRA6;GABRA1;GABRB1;GABRG2;GABRB3 22722:[DB00027 DB02900] DB00027|Gramicidin D ABCB1 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways 22723:[DB00027 DB09073] DB00027|Gramicidin D ABCB1 DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;ABCB1 22724:[DB00027 DB00424] DB00027|Gramicidin D ABCB1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 22725:[DB00027 DB09535] DB00027|Gramicidin D ABCB1 DB09535|Octocrylene ESR1;ESR2 common genes common pathways 22726:[DB00027 DB04021] DB00027|Gramicidin D ABCB1 DB04021|MF268 ACHE common genes common pathways 22727:[DB00027 DB09045] DB00027|Gramicidin D ABCB1 DB09045|Dulaglutide GLP1R common genes common pathways 22728:[DB00027 DB00706] DB00027|Gramicidin D ABCB1 DB00706|Tamsulosin ADRA1A;ADRA1D;ADRA1B;CYP3A4;CYP2D6;ORM1 common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 22729:[DB00027 DB06307] DB00027|Gramicidin D ABCB1 DB06307|Apoptone BCL2 common genes common pathways GO:0042493| response to drug BCL2;ABCB1 GO:0055085| transmembrane transport BCL2;ABCB1 22730:[DB00027 DB09105] DB00027|Gramicidin D ABCB1 DB09105|Asfotase Alfa S1PR1 common genes common pathways 22731:[DB00027 DB12130] DB00027|Gramicidin D ABCB1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways 22732:[DB00027 DB00356] DB00027|Gramicidin D ABCB1 DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0055085| transmembrane transport KCNMA1;ABCB1 GO:0042493| response to drug CYP1A1;ABCB1;CYP2E1;CYP1A2 22733:[DB00027 DB06325] DB00027|Gramicidin D ABCB1 DB06325|Pegpleranib PDGFB common genes common pathways 22734:[DB00027 DB07286] DB00027|Gramicidin D ABCB1 DB07286|BMS-564929 AR common genes common pathways GO:0006810| transport AR;ABCB1 22735:[DB00027 DB04620] DB00027|Gramicidin D ABCB1 DB04620|Cycloleucine GRIN1 common genes common pathways 22736:[DB00027 DB01332] DB00027|Gramicidin D ABCB1 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC22A6;SLC22A8 GO:0006810| transport SLC15A1;ABCB1 22737:[DB00027 DB07344] DB00027|Gramicidin D ABCB1 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways 22738:[DB00027 DB06016] DB00027|Gramicidin D ABCB1 DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2A;HTR2B;DRD2;ABCB1;DRD3 22739:[DB00027 DB09289] DB00027|Gramicidin D ABCB1 DB09289|Tianeptine GRIA1;OPRM1;HTR1A;DRD3;CYP3A4 common genes common pathways GO:0042493| response to drug DRD3;ABCB1 22740:[DB00027 DB06688] DB00027|Gramicidin D ABCB1 DB06688|Sipuleucel-T ACPP common genes common pathways 22741:[DB00027 DB05192] DB00027|Gramicidin D ABCB1 DB05192|MB07811 THRB common genes common pathways 22742:[DB00027 DB04519] DB00027|Gramicidin D ABCB1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0055085| transmembrane transport SLC22A11;SLC22A8;ABCB1;SLC22A6 22743:[DB00027 DB00322] DB00027|Gramicidin D ABCB1 DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;TYMS 22744:[DB00027 DB03664] DB00027|Gramicidin D ABCB1 DB03664|UP5 CMPK1 common genes common pathways 22745:[DB00027 DB08088] DB00027|Gramicidin D ABCB1 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways GO:0006810| transport AR;ABCB1 22746:[DB00027 DB01216] DB00027|Gramicidin D ABCB1 DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;SRD5A1;SRD5A2 22747:[DB00027 DB06730] DB00027|Gramicidin D ABCB1 DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways 22748:[DB00027 DB00191] DB00027|Gramicidin D ABCB1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0042493| response to drug SLC6A4;CYP1A2;SLC6A3;ABCB1;SLC6A2;MAOB GO:0055085| transmembrane transport SLC6A4;SLC6A2;SLC6A3;ABCB1 GO:0006810| transport ABCB1;SLC6A2 22749:[DB00027 DB06650] DB00027|Gramicidin D ABCB1 DB06650|Ofatumumab MS4A1 common genes common pathways 22750:[DB00027 DB00371] DB00027|Gramicidin D ABCB1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;GABRG3;ABCB1 GO:0006810| transport GABRG2;GABRB1;GABRA6;GABRA4;GABRA1;GABRB3;GABRA3;GABRA5;GABRD;GABRB2;ABCB1 22751:[DB00027 DB06684] DB00027|Gramicidin D ABCB1 DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1 22752:[DB00027 DB04409] DB00027|Gramicidin D ABCB1 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways 22753:[DB00027 DB08560] DB00027|Gramicidin D ABCB1 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 22754:[DB00027 DB07917] DB00027|Gramicidin D ABCB1 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways 22755:[DB00027 DB03384] DB00027|Gramicidin D ABCB1 DB03384|Fica CASP7 common genes common pathways 22756:[DB00027 DB00283] DB00027|Gramicidin D ABCB1 DB00283|Clemastine HRH1;CYP2D6 common genes common pathways 22757:[DB00027 DB00931] DB00027|Gramicidin D ABCB1 DB00931|Metacycline ALB common genes common pathways 22758:[DB00027 DB05233] DB00027|Gramicidin D ABCB1 DB05233|AP1081 ESR1 common genes common pathways 22759:[DB00027 DB00903] DB00027|Gramicidin D ABCB1 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0006810| transport SLC12A1;ABCB1 GO:0055085| transmembrane transport SLC12A1;ABCB1;SLC22A6 GO:0042493| response to drug ABCB1;ATP1A1 22760:[DB00027 DB07789] DB00027|Gramicidin D ABCB1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 22761:[DB00027 DB06945] DB00027|Gramicidin D ABCB1 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways 22762:[DB00027 DB01089] DB00027|Gramicidin D ABCB1 DB01089|Deserpidine SLC18A2 common genes common pathways GO:0055085| transmembrane transport SLC18A2;ABCB1 22763:[DB00027 DB13166] DB00027|Gramicidin D ABCB1 DB13166|Zofenopril ACE common genes common pathways 22764:[DB00027 DB01223] DB00027|Gramicidin D ABCB1 DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0042493| response to drug ABCB1;PDE3A;HDAC2;CYP2E1;CYP1A2 22765:[DB00027 DB00861] DB00027|Gramicidin D ABCB1 DB00861|Diflunisal PTGS2;PTGS1;UGT1A8;UGT1A9;TTR;ALB;SLC22A6 common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0042493| response to drug ABCB1;PTGS2 22766:[DB00027 DB00995] DB00027|Gramicidin D ABCB1 DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways 22767:[DB00027 DB00108] DB00027|Gramicidin D ABCB1 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0042493| response to drug ICAM1;ABCB1 22768:[DB00027 DB09236] DB00027|Gramicidin D ABCB1 DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways GO:0055085| transmembrane transport CACNA1C;CACNA1D;CACNA1S;CACNA1F;ABCB1 GO:0006810| transport ABCB1;CACNB1;CACNB3;CACNB4 22769:[DB00027 DB11858] DB00027|Gramicidin D ABCB1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways 22770:[DB00027 DB14132] DB00027|Gramicidin D ABCB1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;ADORA2A;CYP1A2 22771:[DB00027 DB09070] DB00027|Gramicidin D ABCB1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways 22772:[DB00027 DB02462] DB00027|Gramicidin D ABCB1 DB02462|Thiocoumarin NOS2 common genes common pathways 22773:[DB00027 DB00964] DB00027|Gramicidin D ABCB1 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 22774:[DB00027 DB00487] DB00027|Gramicidin D ABCB1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22775:[DB00027 DB07154] DB00027|Gramicidin D ABCB1 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways 22776:[DB00027 DB13881] DB00027|Gramicidin D ABCB1 DB13881|Tisagenlecleucel CD19 common genes common pathways 22777:[DB00027 DB03703] DB00027|Gramicidin D ABCB1 DB03703|Cyclohexanol ADH1B common genes common pathways 22778:[DB00027 DB09203] DB00027|Gramicidin D ABCB1 DB09203|Synephrine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 22779:[DB00027 DB13132] DB00027|Gramicidin D ABCB1 DB13132|Artemisinin CYP2B6 common genes common pathways 22780:[DB00027 DB04852] DB00027|Gramicidin D ABCB1 DB04852|Implitapide MTTP common genes common pathways 22781:[DB00027 DB05920] DB00027|Gramicidin D ABCB1 DB05920|RTA 744 TOP2A common genes common pathways 22782:[DB00027 DB05938] DB00027|Gramicidin D ABCB1 DB05938|Edonerpic APP common genes common pathways 22783:[DB00027 DB12610] DB00027|Gramicidin D ABCB1 DB12610|Ebselen EPHX2 common genes common pathways 22784:[DB00027 DB11397] DB00027|Gramicidin D ABCB1 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0042493| response to drug BCHE;ABCB1 22785:[DB00027 DB00600] DB00027|Gramicidin D ABCB1 DB00600|Monobenzone TYR common genes common pathways 22786:[DB00027 DB03889] DB00027|Gramicidin D ABCB1 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 22787:[DB00027 DB01831] DB00027|Gramicidin D ABCB1 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways 22788:[DB00027 DB01589] DB00027|Gramicidin D ABCB1 DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1 GO:0006810| transport GABRA4;GABRR1;GABRA6;GABRA1;GABRG2;GABRB1;GABRB3;GABRB2;GABRD;GABRR2;GABRA3;GABRA5;ABCB1 22789:[DB00027 DB14527] DB00027|Gramicidin D ABCB1 DB14527|Chromic nitrate CYB5A;TF common genes common pathways 22790:[DB00027 DB08435] DB00027|Gramicidin D ABCB1 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 22791:[DB00027 DB06410] DB00027|Gramicidin D ABCB1 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways 22792:[DB00027 DB01064] DB00027|Gramicidin D ABCB1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0042493| response to drug SOD1;ABCB1;CYP1A1 22793:[DB00027 DB06721] DB00027|Gramicidin D ABCB1 DB06721|Gimatecan SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1 22794:[DB00027 DB04853] DB00027|Gramicidin D ABCB1 DB04853|Binodenoson ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;ABCB1 22795:[DB00027 DB02515] DB00027|Gramicidin D ABCB1 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways 22796:[DB00027 DB03486] DB00027|Gramicidin D ABCB1 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways 22797:[DB00027 DB14529] DB00027|Gramicidin D ABCB1 DB14529|Chromium nicotinate CYB5A;TF common genes common pathways 22798:[DB00027 DB10772] DB00027|Gramicidin D ABCB1 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways GO:0042493| response to drug TGFBR2;TGFB1;ABCB1 22799:[DB00027 DB02107] DB00027|Gramicidin D ABCB1 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 22800:[DB00027 DB04256] DB00027|Gramicidin D ABCB1 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways 22801:[DB00027 DB06538] DB00027|Gramicidin D ABCB1 DB06538|Robalzotan HTR1A common genes common pathways 22802:[DB00027 DB08156] DB00027|Gramicidin D ABCB1 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 22803:[DB00027 DB08190] DB00027|Gramicidin D ABCB1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways 22804:[DB00027 DB08221] DB00027|Gramicidin D ABCB1 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways 22805:[DB00027 DB00633] DB00027|Gramicidin D ABCB1 DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;CYP1A2;CYP2E1 22806:[DB00027 DB04578] DB00027|Gramicidin D ABCB1 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways 22807:[DB00027 DB01349] DB00027|Gramicidin D ABCB1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways 22808:[DB00027 DB11774] DB00027|Gramicidin D ABCB1 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22809:[DB00027 DB04910] DB00027|Gramicidin D ABCB1 DB04910|Oxibendazole TUBB4B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4B 22810:[DB00027 DB08772] DB00027|Gramicidin D ABCB1 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways 22811:[DB00027 DB00471] DB00027|Gramicidin D ABCB1 DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO2B1 22812:[DB00027 DB08222] DB00027|Gramicidin D ABCB1 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways 22813:[DB00027 DB13500] DB00027|Gramicidin D ABCB1 DB13500|Otilonium CYP3A4 common genes common pathways 22814:[DB00027 DB01951] DB00027|Gramicidin D ABCB1 DB01951|Gpi-1046 FKBP1A common genes common pathways 22815:[DB00027 DB09154] DB00027|Gramicidin D ABCB1 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC13A5;SLC25A21;SLC13A2;SLC25A1 GO:0006810| transport ABCB1;SLC13A2 22816:[DB00027 DB00140] DB00027|Gramicidin D ABCB1 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways GO:0042493| response to drug ABCB1;MTHFR GO:0055085| transmembrane transport SLC22A6;ABCB1 22817:[DB00027 DB01231] DB00027|Gramicidin D ABCB1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways 22818:[DB00027 DB00710] DB00027|Gramicidin D ABCB1 DB00710|Ibandronate FDPS common genes common pathways 22819:[DB00027 DB00144] DB00027|Gramicidin D ABCB1 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ATP8A1 22820:[DB00027 DB00511] DB00027|Gramicidin D ABCB1 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1 22821:[DB00027 DB00917] DB00027|Gramicidin D ABCB1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0042493| response to drug ABCB1;ABCC4 GO:0055085| transmembrane transport ABCC5;SLC51B;SLC22A2;SLCO2B1;ABCB1;SLC51A;SLC22A6;SLCO2A1;SLCO1C1;SLCO4A1;SLC22A7;SLC22A11;ABCC4;SLC22A8;SLCO1B1;SLCO3A1;SLCO1A2 GO:0006810| transport ABCC5;ABCB1 22822:[DB00027 DB00331] DB00027|Gramicidin D ABCB1 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC22A1;SLC47A1;SLC47A2;SLC22A3 GO:0055085| transmembrane transport SLC47A1;SLC47A2;SLC22A3;SLC29A4;ABCB1;SLC22A2;SLC22A1 22823:[DB00027 DB03292] DB00027|Gramicidin D ABCB1 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways 22824:[DB00027 DB07700] DB00027|Gramicidin D ABCB1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways 22825:[DB00027 DB01271] DB00027|Gramicidin D ABCB1 DB01271|Idursulfase PLIN3 common genes common pathways 22826:[DB00027 DB04951] DB00027|Gramicidin D ABCB1 DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 22827:[DB00027 DB09230] DB00027|Gramicidin D ABCB1 DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0006810| transport CACNB1;ABCB1 22828:[DB00027 DB00850] DB00027|Gramicidin D ABCB1 DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CALM1;ABCB1 GO:0042493| response to drug DRD1;CYP1A2;ABCB1;DRD2 22829:[DB00027 DB04957] DB00027|Gramicidin D ABCB1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNQ1;KCNH2 GO:0042493| response to drug CYP1A1;ABCB1 22830:[DB00027 DB04919] DB00027|Gramicidin D ABCB1 DB04919|Alfimeprase FGA;FGB common genes common pathways 22831:[DB00027 DB01595] DB00027|Gramicidin D ABCB1 DB01595|Nitrazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;SCN1A;CYP3A4;CYP2E1 common genes common pathways GO:0006810| transport GABRA1;GABRA4;GABRA6;GABRR1;GABRG2;GABRB1;GABRB3;GABRD;GABRB2;GABRA3;GABRA5;GABRR2;ABCB1 GO:0055085| transmembrane transport ABCB1;SCN1A GO:0042493| response to drug ABCB1;CYP2E1;GABRG3 22832:[DB00027 DB05679] DB00027|Gramicidin D ABCB1 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways 22833:[DB00027 DB13203] DB00027|Gramicidin D ABCB1 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22834:[DB00027 DB06479] DB00027|Gramicidin D ABCB1 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22835:[DB00027 DB08885] DB00027|Gramicidin D ABCB1 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways GO:0042493| response to drug ABCB1;VEGFB;PGF 22836:[DB00027 DB03832] DB00027|Gramicidin D ABCB1 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways 22837:[DB00027 DB02353] DB00027|Gramicidin D ABCB1 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways 22838:[DB00027 DB08750] DB00027|Gramicidin D ABCB1 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways 22839:[DB00027 DB01456] DB00027|Gramicidin D ABCB1 DB01456|5-androstenedione CYP3A4 common genes common pathways 22840:[DB00027 DB02691] DB00027|Gramicidin D ABCB1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLCO1B1;SLCO1B3 22841:[DB00027 DB00614] DB00027|Gramicidin D ABCB1 DB00614|Furazolidone MAOB;MAOA common genes common pathways GO:0042493| response to drug ABCB1;MAOB 22842:[DB00027 DB01399] DB00027|Gramicidin D ABCB1 DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 22843:[DB00027 DB05514] DB00027|Gramicidin D ABCB1 DB05514|Cobiprostone CLCN2 common genes common pathways GO:0006810| transport ABCB1;CLCN2 GO:0055085| transmembrane transport ABCB1;CLCN2 22844:[DB00027 DB07831] DB00027|Gramicidin D ABCB1 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways 22845:[DB00027 DB01559] DB00027|Gramicidin D ABCB1 DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;GABRG3 GO:0006810| transport GABRB1;GABRG2;GABRR1;GABRA1;GABRB3;GABRR2;GABRA5;GABRA3;GABRD;GABRB2;ABCB1 22846:[DB00027 DB09091] DB00027|Gramicidin D ABCB1 DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0042493| response to drug HDAC2;ABCB1 22847:[DB00027 DB04794] DB00027|Gramicidin D ABCB1 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 22848:[DB00027 DB00769] DB00027|Gramicidin D ABCB1 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways 22849:[DB00027 DB07396] DB00027|Gramicidin D ABCB1 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways 22850:[DB00027 DB05796] DB00027|Gramicidin D ABCB1 DB05796|Daglutril MME common genes common pathways 22851:[DB00027 DB00078] DB00027|Gramicidin D ABCB1 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 22852:[DB00027 DB09140] DB00027|Gramicidin D ABCB1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways 22853:[DB00027 DB04946] DB00027|Gramicidin D ABCB1 DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A;DRD2;DRD3;DRD1;HTR2A;CYP2E1 22854:[DB00027 DB11614] DB00027|Gramicidin D ABCB1 DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways 22855:[DB00027 DB08259] DB00027|Gramicidin D ABCB1 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways 22856:[DB00027 DB01738] DB00027|Gramicidin D ABCB1 DB01738|Phosphorylcolamine PRKCB common genes common pathways 22857:[DB00027 DB06814] DB00027|Gramicidin D ABCB1 DB06814|Protokylol ADRB2 common genes common pathways 22858:[DB00027 DB07919] DB00027|Gramicidin D ABCB1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways 22859:[DB00027 DB03945] DB00027|Gramicidin D ABCB1 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways 22860:[DB00027 DB09064] DB00027|Gramicidin D ABCB1 DB09064|Ciprofibrate PPARA common genes common pathways 22861:[DB00027 DB06145] DB00027|Gramicidin D ABCB1 DB06145|Spiramycin rplC;CYP3A4 common genes common pathways 22862:[DB00027 DB03451] DB00027|Gramicidin D ABCB1 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways 22863:[DB00027 DB12118] DB00027|Gramicidin D ABCB1 DB12118|Sotatercept ACVR2A common genes common pathways 22864:[DB00027 DB02039] DB00027|Gramicidin D ABCB1 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways 22865:[DB00027 DB05234] DB00027|Gramicidin D ABCB1 DB05234|LGD2941 AR common genes common pathways GO:0006810| transport ABCB1;AR 22866:[DB00027 DB05542] DB00027|Gramicidin D ABCB1 DB05542|Naronapride HTR4 common genes common pathways 22867:[DB00027 DB04757] DB00027|Gramicidin D ABCB1 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 22868:[DB00027 DB03435] DB00027|Gramicidin D ABCB1 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways 22869:[DB00027 DB08159] DB00027|Gramicidin D ABCB1 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 22870:[DB00027 DB08101] DB00027|Gramicidin D ABCB1 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0006810| transport ABCB1;TTR 22871:[DB00027 DB00580] DB00027|Gramicidin D ABCB1 DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 GO:2001225| regulation of chloride transport ABCB1;CA2 22872:[DB00027 DB12688] DB00027|Gramicidin D ABCB1 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways GO:0042493| response to drug EEF2;ABCB1 22873:[DB00027 DB00794] DB00027|Gramicidin D ABCB1 DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0006810| transport GABRA3;GABRA5;GABRD;GABRB2;ABCB1;GABRG2;GABRB1;GABRA6;GRIK2;GABRA4;GABRA1;GABRB3 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0042493| response to drug CYP1A2;GABRG3;UGT1A1;ABCB1 22874:[DB00027 DB02282] DB00027|Gramicidin D ABCB1 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 22875:[DB00027 DB06039] DB00027|Gramicidin D ABCB1 DB06039|PA-1050040 gag common genes common pathways 22876:[DB00027 DB02311] DB00027|Gramicidin D ABCB1 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways 22877:[DB00027 DB04069] DB00027|Gramicidin D ABCB1 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways 22878:[DB00027 DB00178] DB00027|Gramicidin D ABCB1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC15A2 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0042493| response to drug ABCB1;BCHE 22879:[DB00027 DB00592] DB00027|Gramicidin D ABCB1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0006810| transport ABCB1;GABRB3 22880:[DB00027 DB01160] DB00027|Gramicidin D ABCB1 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways GO:0055085| transmembrane transport SLC22A7;SLC22A11;SLCO3A1;SLC22A8;ABCB1;SLC22A2;SLC22A6;SLCO2A1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 22881:[DB00027 DB13996] DB00027|Gramicidin D ABCB1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 22882:[DB00027 DB09227] DB00027|Gramicidin D ABCB1 DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CACNA1C;ABCB1 22883:[DB00027 DB00815] DB00027|Gramicidin D ABCB1 DB00815|Sodium lauryl sulfate ALB common genes common pathways 22884:[DB00027 DB00839] DB00027|Gramicidin D ABCB1 DB00839|Tolazamide ABCC8;KCNJ11;CYP2C9 common genes common pathways GO:0055085| transmembrane transport KCNJ11;ABCC8;ABCB1 GO:0042493| response to drug ABCC8;KCNJ11;ABCB1 22885:[DB00027 DB03253] DB00027|Gramicidin D ABCB1 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways 22886:[DB00027 DB00925] DB00027|Gramicidin D ABCB1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A GO:0055085| transmembrane transport CALM1;SLC22A3;SLC22A2;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2 22887:[DB00027 DB12418] DB00027|Gramicidin D ABCB1 DB12418|Saccharin CA3 common genes common pathways 22888:[DB00027 DB07837] DB00027|Gramicidin D ABCB1 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways 22889:[DB00027 DB01811] DB00027|Gramicidin D ABCB1 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways 22890:[DB00027 DB00449] DB00027|Gramicidin D ABCB1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0042493| response to drug BCHE;ADRA1A;ABCB1 22891:[DB00027 DB12061] DB00027|Gramicidin D ABCB1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0042493| response to drug ABCB1;DRD2;DRD3 22892:[DB00027 DB06215] DB00027|Gramicidin D ABCB1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways 22893:[DB00027 DB01444] DB00027|Gramicidin D ABCB1 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes common pathways 22894:[DB00027 DB09167] DB00027|Gramicidin D ABCB1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0042493| response to drug SLC6A2;ABCB1;ADRA1A;CYP1A2;HTR2A;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A2;SLC6A4 22895:[DB00027 DB00446] DB00027|Gramicidin D ABCB1 DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 22896:[DB00027 DB05417] DB00027|Gramicidin D ABCB1 DB05417|GW 468816 GLRA1 common genes common pathways 22897:[DB00027 DB02338] DB00027|Gramicidin D ABCB1 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways 22898:[DB00027 DB01973] DB00027|Gramicidin D ABCB1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 22899:[DB00027 DB02508] DB00027|Gramicidin D ABCB1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways 22900:[DB00027 DB00319] DB00027|Gramicidin D ABCB1 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A8 22901:[DB00027 DB09340] DB00027|Gramicidin D ABCB1 DB09340|Tyropanoic acid GUSB common genes common pathways 22902:[DB00027 DB00716] DB00027|Gramicidin D ABCB1 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle HSP90AA1;ABCB1 22903:[DB00027 DB00825] DB00027|Gramicidin D ABCB1 DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0042493| response to drug TRPA1;ABCB1 GO:0006810| transport CACNB3;ABCB1;CACNB1;CACNB4 GO:0055085| transmembrane transport TRPM8;ABCB1;CACNA1F;TRPA1;CACNA1S;CACNA1D;CACNA1C;TRPV3 22904:[DB00027 DB04685] DB00027|Gramicidin D ABCB1 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways 22905:[DB00027 DB01105] DB00027|Gramicidin D ABCB1 DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;SLC6A2 GO:0042493| response to drug SLC6A4;SLC6A2;ABCB1;SLC6A3 22906:[DB00027 DB00030] DB00027|Gramicidin D ABCB1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways 22907:[DB00027 DB00796] DB00027|Gramicidin D ABCB1 DB00796|Candesartan cilexetil AGTR1;CYP2C9;CYP2C8;UGT1A3;PTGS1;ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 22908:[DB00027 DB13967] DB00027|Gramicidin D ABCB1 DB13967|Patent Blue ALB common genes common pathways 22909:[DB00027 DB07696] DB00027|Gramicidin D ABCB1 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways GO:0042493| response to drug CASP3;ABCB1 22910:[DB00027 DB13884] DB00027|Gramicidin D ABCB1 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways 22911:[DB00027 DB00275] DB00027|Gramicidin D ABCB1 DB00275|Olmesartan AGTR1;ABCC2;SLCO1B3;SLCO1B1;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC2;ABCB11;SLCO1B1;SLCO1B3 GO:0006810| transport ABCB11;ABCC2;ABCB1 GO:0042493| response to drug ABCB1;ABCC2 GO:0006855| drug transmembrane transport ABCB1;ABCC2 22912:[DB00027 DB14600] DB00027|Gramicidin D ABCB1 DB14600|Edetate disodium anhydrous ADA;CYP1A2;PON3;CYP19A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;ADA 22913:[DB00027 DB06457] DB00027|Gramicidin D ABCB1 DB06457|Tecastemizole KCNH2 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCB1 22914:[DB00027 DB05413] DB00027|Gramicidin D ABCB1 DB05413|Tifuvirtide SERPINA5 common genes common pathways 22915:[DB00027 DB07117] DB00027|Gramicidin D ABCB1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 22916:[DB00027 DB06371] DB00027|Gramicidin D ABCB1 DB06371|Siplizumab CD2 common genes common pathways 22917:[DB00027 DB06602] DB00027|Gramicidin D ABCB1 DB06602|Reslizumab IL5 common genes common pathways 22918:[DB00027 DB04119] DB00027|Gramicidin D ABCB1 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways 22919:[DB00027 DB07930] DB00027|Gramicidin D ABCB1 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways 22920:[DB00027 DB11949] DB00027|Gramicidin D ABCB1 DB11949|Vestipitant TACR1 common genes common pathways 22921:[DB00027 DB08059] DB00027|Gramicidin D ABCB1 DB08059|Wortmannin PIK3CG;PLK1;PIK3R1;PIK3CA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 22922:[DB00027 DB00734] DB00027|Gramicidin D ABCB1 DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0042493| response to drug HTR2C;ABCB1;ADRA1A;DRD2;DRD3;DRD1;HTR2A 22923:[DB00027 DB07500] DB00027|Gramicidin D ABCB1 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways 22924:[DB00027 DB01704] DB00027|Gramicidin D ABCB1 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways 22925:[DB00027 DB12874] DB00027|Gramicidin D ABCB1 DB12874|Quizartinib FLT3 common genes common pathways 22926:[DB00027 DB05750] DB00027|Gramicidin D ABCB1 DB05750|AVE-1625 CNR1 common genes common pathways 22927:[DB00027 DB05394] DB00027|Gramicidin D ABCB1 DB05394|Corticorelin DBH common genes common pathways 22928:[DB00027 DB04115] DB00027|Gramicidin D ABCB1 DB04115|Berberine BIRC5 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;BIRC5 22929:[DB00027 DB02660] DB00027|Gramicidin D ABCB1 DB02660|Filaminast PDE4B common genes common pathways 22930:[DB00027 DB00465] DB00027|Gramicidin D ABCB1 DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 22931:[DB00027 DB00720] DB00027|Gramicidin D ABCB1 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0006810| transport SLC25A5;ABCB1;SLC25A4 GO:0055085| transmembrane transport SLC25A6;SLC25A4;SLC25A5;ABCB1 GO:0042493| response to drug ABCB1;PTGS2 22932:[DB00027 DB00653] DB00027|Gramicidin D ABCB1 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways GO:0055085| transmembrane transport CACNA1S;ABCB1;CACNA1C GO:0006810| transport ABCB1;CACNB1;CACNG1 22933:[DB00027 DB01147] DB00027|Gramicidin D ABCB1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport SLC15A2;SLC22A6;SLC15A1;ABCB1 22934:[DB00027 DB02932] DB00027|Gramicidin D ABCB1 DB02932|(R)-Bicalutamide AR common genes common pathways GO:0006810| transport AR;ABCB1 22935:[DB00027 DB00573] DB00027|Gramicidin D ABCB1 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;PPARG 22936:[DB00027 DB00120] DB00027|Gramicidin D ABCB1 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0042493| response to drug ABCB1;TH GO:0006810| transport SLC7A8;ABCB1 GO:0055085| transmembrane transport SLC16A10;ABCB1 22937:[DB00027 DB07677] DB00027|Gramicidin D ABCB1 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 22938:[DB00027 DB09329] DB00027|Gramicidin D ABCB1 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways 22939:[DB00027 DB02758] DB00027|Gramicidin D ABCB1 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways 22940:[DB00027 DB00788] DB00027|Gramicidin D ABCB1 DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;PTGS2;CYP1A2 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLCO1A2;ABCB11 GO:0006810| transport ABCB1;ABCB11 22941:[DB00027 DB07509] DB00027|Gramicidin D ABCB1 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 22942:[DB00027 DB01647] DB00027|Gramicidin D ABCB1 DB01647|Daxalipram PDE4B common genes common pathways 22943:[DB00027 DB00869] DB00027|Gramicidin D ABCB1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 22944:[DB00027 DB03849] DB00027|Gramicidin D ABCB1 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways 22945:[DB00027 DB06674] DB00027|Gramicidin D ABCB1 DB06674|Golimumab TNF common genes common pathways 22946:[DB00027 DB07701] DB00027|Gramicidin D ABCB1 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways 22947:[DB00027 DB11636] DB00027|Gramicidin D ABCB1 DB11636|Nomegestrol CYP3A4 common genes common pathways 22948:[DB00027 DB07561] DB00027|Gramicidin D ABCB1 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 22949:[DB00027 DB00147] DB00027|Gramicidin D ABCB1 DB00147|Pyridoxal PDXK common genes common pathways 22950:[DB00027 DB01541] DB00027|Gramicidin D ABCB1 DB01541|Boldenone AR common genes common pathways GO:0006810| transport ABCB1;AR 22951:[DB00027 DB00998] DB00027|Gramicidin D ABCB1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;HTR1B 22952:[DB00027 DB00133] DB00027|Gramicidin D ABCB1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0042493| response to drug ABCB1;SRR GO:0055085| transmembrane transport SLC16A10;ABCB1 22953:[DB00027 DB13749] DB00027|Gramicidin D ABCB1 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ADCY1;ATP1A1 22954:[DB00027 DB12089] DB00027|Gramicidin D ABCB1 DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways 22955:[DB00027 DB07173] DB00027|Gramicidin D ABCB1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 22956:[DB00027 DB09061] DB00027|Gramicidin D ABCB1 DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006810| transport ABCC1;TRPV1;CACNA1I;ABCB1;ABCG2;TRPV2 GO:0055085| transmembrane transport TRPV3;CACNA1H;TRPV2;TRPA1;ABCC1;CACNA1G;TRPM8;ABCG2;TRPV4;CACNA1I;ABCB1;VDAC1;TRPV1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;CYP1A1;PPARG;ABCB1;ABCG2;PTGS2;CYP1A2;HTR2A;SOD1;CAT 22957:[DB00027 DB02890] DB00027|Gramicidin D ABCB1 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways 22958:[DB00027 DB00066] DB00027|Gramicidin D ABCB1 DB00066|Follitropin FSHR common genes common pathways 22959:[DB00027 DB01873] DB00027|Gramicidin D ABCB1 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4A;TUBA4A;TUBA1A;TUBB;TUBB4B 22960:[DB00027 DB11595] DB00027|Gramicidin D ABCB1 DB11595|Atezolizumab CD274 common genes common pathways 22961:[DB00027 DB01751] DB00027|Gramicidin D ABCB1 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 22962:[DB00027 DB11135] DB00027|Gramicidin D ABCB1 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways 22963:[DB00027 DB02774] DB00027|Gramicidin D ABCB1 DB02774|1,3-Propandiol ARF1 common genes common pathways 22964:[DB00027 DB04856] DB00027|Gramicidin D ABCB1 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes common pathways 22965:[DB00027 DB01582] DB00027|Gramicidin D ABCB1 DB01582|Sulfamethazine ALB common genes common pathways 22966:[DB00027 DB00397] DB00027|Gramicidin D ABCB1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0042493| response to drug ABCB1;DRD1 22967:[DB00027 DB03944] DB00027|Gramicidin D ABCB1 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 22968:[DB00027 DB03413] DB00027|Gramicidin D ABCB1 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways 22969:[DB00027 DB04466] DB00027|Gramicidin D ABCB1 DB04466|SR12813 NR1I2 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 22970:[DB00027 DB02115] DB00027|Gramicidin D ABCB1 DB02115|Daidzin ALDH2;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 22971:[DB00027 DB09310] DB00027|Gramicidin D ABCB1 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 22972:[DB00027 DB05012] DB00027|Gramicidin D ABCB1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug ABCB1;SLC6A2 22973:[DB00027 DB00728] DB00027|Gramicidin D ABCB1 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A1;SLCO1A2 22974:[DB00027 DB02636] DB00027|Gramicidin D ABCB1 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways 22975:[DB00027 DB04436] DB00027|Gramicidin D ABCB1 DB04436|3-Fluorotyrosine SOD2 common genes common pathways 22976:[DB00027 DB13876] DB00027|Gramicidin D ABCB1 DB13876|Brofaromine MAOA common genes common pathways 22977:[DB00027 DB09047] DB00027|Gramicidin D ABCB1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways 22978:[DB00027 DB00643] DB00027|Gramicidin D ABCB1 DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 GO:0000086| G2/M transition of mitotic cell cycle TUBB4B;TUBA1A;ABCB1 22979:[DB00027 DB00612] DB00027|Gramicidin D ABCB1 DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways 22980:[DB00027 DB01666] DB00027|Gramicidin D ABCB1 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways 22981:[DB00027 DB04121] DB00027|Gramicidin D ABCB1 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways 22982:[DB00027 DB06249] DB00027|Gramicidin D ABCB1 DB06249|Arzoxifene ESR1;ESR2 common genes common pathways 22983:[DB00027 DB04941] DB00027|Gramicidin D ABCB1 DB04941|Crofelemer CFTR;ANO1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CFTR 22984:[DB00027 DB06133] DB00027|Gramicidin D ABCB1 DB06133|Dimethylcurcumin AR common genes common pathways GO:0006810| transport ABCB1;AR 22985:[DB00027 DB07193] DB00027|Gramicidin D ABCB1 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways 22986:[DB00027 DB08922] DB00027|Gramicidin D ABCB1 DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0042493| response to drug ADRA1A;DRD2;ABCB1;CYP1A1;HTR2A 22987:[DB00027 DB07754] DB00027|Gramicidin D ABCB1 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways 22988:[DB00027 DB12379] DB00027|Gramicidin D ABCB1 DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 22989:[DB00027 DB01576] DB00027|Gramicidin D ABCB1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A2;SLC18A2 GO:0042493| response to drug SLC6A2;SLC6A3;ADRA1A;ABCB1 22990:[DB00027 DB01068] DB00027|Gramicidin D ABCB1 DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0042493| response to drug TSPO;CYP2E1;GABRG3;ABCB1 GO:0006810| transport ABCB1;GABRA3;GABRA5;GABRD;GABRB2;GABRB3;GABRB1;GABRG2;GABRA1;GABRA4;GABRA6 22991:[DB00027 DB03615] DB00027|Gramicidin D ABCB1 DB03615|Ribostamycin P4HB;rpsL common genes common pathways 22992:[DB00027 DB00647] DB00027|Gramicidin D ABCB1 DB00647|Dextropropoxyphene OPRM1;OPRD1;OPRK1;CES1;CYP3A4;CYP2D6;CYP2C8 common genes common pathways 22993:[DB00027 DB11560] DB00027|Gramicidin D ABCB1 DB11560|Lesinurad SLC22A12;SLC22A11;CYP2C9 common genes common pathways GO:0042493| response to drug SLC22A12;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A11;SLC22A12 22994:[DB00027 DB13999] DB00027|Gramicidin D ABCB1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0042493| response to drug ABCB1;CALR 22995:[DB00027 DB11598] DB00027|Gramicidin D ABCB1 DB11598|Antithrombin III human SERPINC1 common genes common pathways 22996:[DB00027 DB06205] DB00027|Gramicidin D ABCB1 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes common pathways GO:0042493| response to drug TGFB1;ABCB1 22997:[DB00027 DB11450] DB00027|Gramicidin D ABCB1 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 22998:[DB00027 DB01838] DB00027|Gramicidin D ABCB1 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways GO:0006810| transport ABCB1;TTR 22999:[DB00027 DB08020] DB00027|Gramicidin D ABCB1 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways 23000:[DB00027 DB02236] DB00027|Gramicidin D ABCB1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways 23001:[DB00027 DB01185] DB00027|Gramicidin D ABCB1 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0042493| response to drug ABCB1;HSD11B2 GO:0006810| transport AR;ABCB1 23002:[DB00027 DB00606] DB00027|Gramicidin D ABCB1 DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0006810| transport ABCB1;FXYD2 GO:2001225| regulation of chloride transport ABCB1;CA2 23003:[DB00027 DB01756] DB00027|Gramicidin D ABCB1 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 23004:[DB00027 DB08971] DB00027|Gramicidin D ABCB1 DB08971|Fluocortolone CYP3A4 common genes common pathways 23005:[DB00027 DB06926] DB00027|Gramicidin D ABCB1 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 23006:[DB00027 DB00999] DB00027|Gramicidin D ABCB1 DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0006810| transport SLC12A3;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC12A3;KCNMA1 23007:[DB00027 DB06691] DB00027|Gramicidin D ABCB1 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A5;SLC22A4 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 23008:[DB00027 DB13488] DB00027|Gramicidin D ABCB1 DB13488|Bencyclane CYP3A4 common genes common pathways 23009:[DB00027 DB07318] DB00027|Gramicidin D ABCB1 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways 23010:[DB00027 DB08087] DB00027|Gramicidin D ABCB1 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways GO:0006810| transport AR;ABCB1 23011:[DB00027 DB00146] DB00027|Gramicidin D ABCB1 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways 23012:[DB00027 DB06210] DB00027|Gramicidin D ABCB1 DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0042493| response to drug CYP1A2;UGT1A1;ABCB1;ABCG2 GO:0055085| transmembrane transport ABCB1;ABCG2;SLCO1B1 GO:0006810| transport ABCG2;ABCB1 23013:[DB00027 DB08872] DB00027|Gramicidin D ABCB1 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways GO:0055085| transmembrane transport SLC5A6;SLC5A8;ABCB1 GO:0006810| transport SLC5A6;ABCB1 23014:[DB00027 DB06421] DB00027|Gramicidin D ABCB1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways 23015:[DB00027 DB13133] DB00027|Gramicidin D ABCB1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0042493| response to drug ABCB1;COL1A1 23016:[DB00027 DB07977] DB00027|Gramicidin D ABCB1 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 23017:[DB00027 DB00233] DB00027|Gramicidin D ABCB1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0042493| response to drug CHUK;PTGS2;ABCB1 23018:[DB00027 DB03183] DB00027|Gramicidin D ABCB1 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 23019:[DB00027 DB11606] DB00027|Gramicidin D ABCB1 DB11606|Susoctocog alfa VWF common genes common pathways 23020:[DB00027 DB05155] DB00027|Gramicidin D ABCB1 DB05155|CR665 OPRK1 common genes common pathways 23021:[DB00027 DB09080] DB00027|Gramicidin D ABCB1 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways 23022:[DB00027 DB00561] DB00027|Gramicidin D ABCB1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0042493| response to drug KCNK3;ABCB1 23023:[DB00027 DB02144] DB00027|Gramicidin D ABCB1 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways 23024:[DB00027 DB11455] DB00027|Gramicidin D ABCB1 DB11455|Robenacoxib PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23025:[DB00027 DB01357] DB00027|Gramicidin D ABCB1 DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways 23026:[DB00027 DB06654] DB00027|Gramicidin D ABCB1 DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCG2;SLCO3A1 GO:0006810| transport ABCB1;ABCG2 GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1;ABCG2;MAOB;CYP1A1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 23027:[DB00027 DB12598] DB00027|Gramicidin D ABCB1 DB12598|Nafamostat F2;F10;F12;PRSS1;KLK1;ICAM1;SLC22A1;SLC22A2 common genes common pathways GO:0042493| response to drug ICAM1;ABCB1 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCB1 23028:[DB00027 DB02553] DB00027|Gramicidin D ABCB1 DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways 23029:[DB00027 DB04572] DB00027|Gramicidin D ABCB1 DB04572|Thiotepa CYP2B6;CYP3A4;BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCB1 23030:[DB00027 DB08529] DB00027|Gramicidin D ABCB1 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 23031:[DB00027 DB09266] DB00027|Gramicidin D ABCB1 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways 23032:[DB00027 DB02011] DB00027|Gramicidin D ABCB1 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways GO:0042493| response to drug OTC;ABCB1 23033:[DB00027 DB04709] DB00027|Gramicidin D ABCB1 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways GO:0006810| transport AR;ABCB1 23034:[DB00027 DB01612] DB00027|Gramicidin D ABCB1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways 23035:[DB00027 DB01777] DB00027|Gramicidin D ABCB1 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways 23036:[DB00027 DB09220] DB00027|Gramicidin D ABCB1 DB09220|Nicorandil ABCC9 common genes common pathways GO:0055085| transmembrane transport ABCC9;ABCB1 GO:0042493| response to drug ABCB1;ABCC9 23037:[DB00027 DB14518] DB00027|Gramicidin D ABCB1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 23038:[DB00027 DB07684] DB00027|Gramicidin D ABCB1 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways 23039:[DB00027 DB07300] DB00027|Gramicidin D ABCB1 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways 23040:[DB00027 DB12733] DB00027|Gramicidin D ABCB1 DB12733|Dipraglurant GRM5 common genes common pathways 23041:[DB00027 DB02735] DB00027|Gramicidin D ABCB1 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways 23042:[DB00027 DB00867] DB00027|Gramicidin D ABCB1 DB00867|Ritodrine ADRB2;PGD common genes common pathways 23043:[DB00027 DB00169] DB00027|Gramicidin D ABCB1 DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 23044:[DB00027 DB02507] DB00027|Gramicidin D ABCB1 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways 23045:[DB00027 DB06150] DB00027|Gramicidin D ABCB1 DB06150|Sulfadimethoxine CYP2C9 common genes common pathways 23046:[DB00027 DB03169] DB00027|Gramicidin D ABCB1 DB03169|(S)-Hmg-Coa HMGCR common genes common pathways 23047:[DB00027 DB01586] DB00027|Gramicidin D ABCB1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0006810| transport ABCB11;ABCC2;SLC10A2;SLC10A1;ABCB1 GO:0055085| transmembrane transport ABCC4;SLCO1A2;ABCB11;ABCB1;SLC10A1;SLC10A2;ABCC2 GO:0042493| response to drug ABCB1;ABCC2;ABCC4;CYP2E1 GO:0006855| drug transmembrane transport ABCB1;ABCC2 23048:[DB00027 DB00880] DB00027|Gramicidin D ABCB1 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0055085| transmembrane transport SLC22A6;ABCB1;SLC12A3 GO:0006810| transport SLC12A3;ABCB1 23049:[DB00027 DB05495] DB00027|Gramicidin D ABCB1 DB05495|PG-530742 MMP9 common genes common pathways 23050:[DB00027 DB11113] DB00027|Gramicidin D ABCB1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways 23051:[DB00027 DB12339] DB00027|Gramicidin D ABCB1 DB12339|Radezolid RRBP1;NIP7 common genes common pathways 23052:[DB00027 DB11085] DB00027|Gramicidin D ABCB1 DB11085|Resorcinol TPO common genes common pathways 23053:[DB00027 DB00372] DB00027|Gramicidin D ABCB1 DB00372|Thiethylperazine DRD2;DRD1;DRD4 common genes common pathways GO:0042493| response to drug DRD2;ABCB1;DRD1 23054:[DB00027 DB13772] DB00027|Gramicidin D ABCB1 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23055:[DB00027 DB12267] DB00027|Gramicidin D ABCB1 DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0006855| drug transmembrane transport ABCB5;SLC47A2;SLC47A1;SLC22A1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB5;ABCB1;ABCG2 GO:0042493| response to drug ABCG2;ABCB1 GO:0055085| transmembrane transport SLC22A1;ABCG2;ABCB1;ABCB5;SLC47A2;SLC47A1 GO:0006810| transport ABCB1;ABCG2 23056:[DB00027 DB03866] DB00027|Gramicidin D ABCB1 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23057:[DB00027 DB06077] DB00027|Gramicidin D ABCB1 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:0042493| response to drug HTR2A;DRD2;ABCB1 23058:[DB00027 DB03085] DB00027|Gramicidin D ABCB1 DB03085|Glycolic acid G6PD;thiO common genes common pathways 23059:[DB00027 DB12579] DB00027|Gramicidin D ABCB1 DB12579|JNJ-37822681 DRD2 common genes common pathways GO:0042493| response to drug ABCB1;DRD2 23060:[DB00027 DB03773] DB00027|Gramicidin D ABCB1 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A1;SLC16A7 23061:[DB00027 DB09074] DB00027|Gramicidin D ABCB1 DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways 23062:[DB00027 DB07460] DB00027|Gramicidin D ABCB1 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways 23063:[DB00027 DB05116] DB00027|Gramicidin D ABCB1 DB05116|Thymectacin TYMS common genes common pathways GO:0042493| response to drug TYMS;ABCB1 23064:[DB00027 DB00411] DB00027|Gramicidin D ABCB1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways 23065:[DB00027 DB00918] DB00027|Gramicidin D ABCB1 DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes common pathways GO:0042493| response to drug CYP2E1;HTR1B;ABCB1 23066:[DB00027 DB00957] DB00027|Gramicidin D ABCB1 DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0042493| response to drug ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0006810| transport AR;ABCB1;ABCC2 23067:[DB00027 DB04860] DB00027|Gramicidin D ABCB1 DB04860|Isatoribine TLR7 common genes common pathways 23068:[DB00027 DB00841] DB00027|Gramicidin D ABCB1 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A;COMT 23069:[DB00027 DB08228] DB00027|Gramicidin D ABCB1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways 23070:[DB00027 DB05046] DB00027|Gramicidin D ABCB1 DB05046|V1003 OPRK1;OPRM1 common genes common pathways 23071:[DB00027 DB06901] DB00027|Gramicidin D ABCB1 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 23072:[DB00027 DB07691] DB00027|Gramicidin D ABCB1 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways 23073:[DB00027 DB01214] DB00027|Gramicidin D ABCB1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways 23074:[DB00027 DB00044] DB00027|Gramicidin D ABCB1 DB00044|Lutropin alfa LHCGR common genes common pathways 23075:[DB00027 DB08808] DB00027|Gramicidin D ABCB1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways 23076:[DB00027 DB07693] DB00027|Gramicidin D ABCB1 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways GO:0006810| transport TTR;ABCB1 23077:[DB00027 DB14059] DB00027|Gramicidin D ABCB1 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0042493| response to drug PTGS2;RELA;ABCB1 23078:[DB00027 DB06064] DB00027|Gramicidin D ABCB1 DB06064|KAI-1455 PRKCE common genes common pathways 23079:[DB00027 DB07517] DB00027|Gramicidin D ABCB1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways 23080:[DB00027 DB08157] DB00027|Gramicidin D ABCB1 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 23081:[DB00027 DB01309] DB00027|Gramicidin D ABCB1 DB01309|Insulin Glulisine INSR common genes common pathways 23082:[DB00027 DB00040] DB00027|Gramicidin D ABCB1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 23083:[DB00027 DB00309] DB00027|Gramicidin D ABCB1 DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways 23084:[DB00027 DB11087] DB00027|Gramicidin D ABCB1 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 23085:[DB00027 DB06736] DB00027|Gramicidin D ABCB1 DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 23086:[DB00027 DB11988] DB00027|Gramicidin D ABCB1 DB11988|Ocrelizumab MS4A1 common genes common pathways 23087:[DB00027 DB00625] DB00027|Gramicidin D ABCB1 DB00625|Efavirenz pol;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP2C8;UGT1A1;ALB;ABCB11;SLC22A1 common genes common pathways GO:0042493| response to drug CYP1A2;UGT1A1;ABCB1 GO:0006810| transport ABCB11;ABCB1 GO:0055085| transmembrane transport SLC22A1;ABCB1;ABCB11 GO:0006855| drug transmembrane transport ABCB1;SLC22A1 23088:[DB00027 DB01700] DB00027|Gramicidin D ABCB1 DB01700|AICA ribonucleotide ATIC common genes common pathways 23089:[DB00027 DB05455] DB00027|Gramicidin D ABCB1 DB05455|SR 121463 AVPR1B common genes common pathways 23090:[DB00027 DB14034] DB00027|Gramicidin D ABCB1 DB14034|Darglitazone PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 23091:[DB00027 DB07559] DB00027|Gramicidin D ABCB1 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 23092:[DB00027 DB00640] DB00027|Gramicidin D ABCB1 DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways GO:0042493| response to drug ABCB1;ADORA2A;ADA 23093:[DB00027 DB05018] DB00027|Gramicidin D ABCB1 DB05018|Migalastat GLA;UGT1A1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 23094:[DB00027 DB00674] DB00027|Gramicidin D ABCB1 DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug BCHE;ABCB1 GO:0006810| transport ABCB1;CHRNA1;CHRNG;CHRND;CHRNB3;CHRNA6;CHRNE 23095:[DB00027 DB08692] DB00027|Gramicidin D ABCB1 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 23096:[DB00027 DB03962] DB00027|Gramicidin D ABCB1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways 23097:[DB00027 DB06153] DB00027|Gramicidin D ABCB1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1;HTR1B;HTR2B;HTR2C;HTR2A 23098:[DB00027 DB08736] DB00027|Gramicidin D ABCB1 DB08736|S,R-Warfarin alcohol ALB common genes common pathways 23099:[DB00027 DB00695] DB00027|Gramicidin D ABCB1 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2;SLC22A5 GO:0006810| transport SLC12A1;ABCC2;ABCB1 GO:0055085| transmembrane transport SLC12A1;SLC22A11;SLC22A8;SLC22A5;ABCB1;ABCC2;SLC22A6;SLCO2A1 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0042493| response to drug UGT1A1;ABCB1;ABCC2 23100:[DB00027 DB00911] DB00027|Gramicidin D ABCB1 DB00911|Tinidazole CYP3A4;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0006810| transport ABCB1;ABCB11 23101:[DB00027 DB09129] DB00027|Gramicidin D ABCB1 DB09129|Chromic chloride INSR common genes common pathways 23102:[DB00027 DB06796] DB00027|Gramicidin D ABCB1 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways 23103:[DB00027 DB06533] DB00027|Gramicidin D ABCB1 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 23104:[DB00027 DB06472] DB00027|Gramicidin D ABCB1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways 23105:[DB00027 DB07247] DB00027|Gramicidin D ABCB1 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways 23106:[DB00027 DB07140] DB00027|Gramicidin D ABCB1 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 23107:[DB00027 DB00384] DB00027|Gramicidin D ABCB1 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23108:[DB00027 DB05916] DB00027|Gramicidin D ABCB1 DB05916|CT-011 PDCD1 common genes common pathways 23109:[DB00027 DB07814] DB00027|Gramicidin D ABCB1 DB07814|Gibberellic acid AADACL2 common genes common pathways 23110:[DB00027 DB01902] DB00027|Gramicidin D ABCB1 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways 23111:[DB00027 DB02568] DB00027|Gramicidin D ABCB1 DB02568|Peldesine PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 23112:[DB00027 DB00906] DB00027|Gramicidin D ABCB1 DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0006810| transport SLC6A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A1 23113:[DB00027 DB06750] DB00027|Gramicidin D ABCB1 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3 23114:[DB00027 DB00743] DB00027|Gramicidin D ABCB1 DB00743|Gadobenic acid ALB common genes common pathways 23115:[DB00027 DB03609] DB00027|Gramicidin D ABCB1 DB03609|3-Deoxyguanosine PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 23116:[DB00027 DB13949] DB00027|Gramicidin D ABCB1 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways GO:0042493| response to drug CALR;ABCB1 23117:[DB00027 DB08811] DB00027|Gramicidin D ABCB1 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0042493| response to drug PDE3A;ABCB1 23118:[DB00027 DB01092] DB00027|Gramicidin D ABCB1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0042493| response to drug ATP1A1;CYP1A1;ATP1A3;ABCB1 GO:0055085| transmembrane transport SLCO4C1;ABCB1;SLCO1C1;SLCO1B3;SLC22A8;SLCO1B1;SLCO1A2 23119:[DB00027 DB01428] DB00027|Gramicidin D ABCB1 DB01428|Oxybenzone PGR;AR;ESR1;ESR2 common genes common pathways GO:0006810| transport AR;ABCB1 23120:[DB00027 DB01077] DB00027|Gramicidin D ABCB1 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways GO:0006810| transport ATP6V1A;ABCB1 23121:[DB00027 DB03255] DB00027|Gramicidin D ABCB1 DB03255|Phenol cobT;ALB common genes common pathways 23122:[DB00027 DB05125] DB00027|Gramicidin D ABCB1 DB05125|SC12267 DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 23123:[DB00027 DB05487] DB00027|Gramicidin D ABCB1 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways 23124:[DB00027 DB00942] DB00027|Gramicidin D ABCB1 DB00942|Cycrimine CHRM1 common genes common pathways 23125:[DB00027 DB02761] DB00027|Gramicidin D ABCB1 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways 23126:[DB00027 DB12010] DB00027|Gramicidin D ABCB1 DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle MELK;CHEK2;ABCB1;CLASP1;WEE1;PKMYT1;LATS1;PLK3;PLK1;CIT;AURKA;PRKACA;PLK4;CDK1;NEK2 GO:0055085| transmembrane transport ABCB5;ABCG2;ABCB1;CSN3 GO:0006810| transport ABCG2;ABCB1 GO:0042493| response to drug CDK1;CDK4;TGFBR2;SRC;RET;UGT1A1;FYN;LYN;NTRK1;ABCB1;MAP2K6;LCK;PTK2B;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCB5 GO:0042908| xenobiotic transport ABCB5;ABCB1;ABCG2 23127:[DB00027 DB08077] DB00027|Gramicidin D ABCB1 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways 23128:[DB00027 DB14533] DB00027|Gramicidin D ABCB1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0055085| transmembrane transport APOA1;ABCB1 GO:0006810| transport ABCB1;TTR GO:0042493| response to drug MGMT;SOD1;NME1;TP53;MDM2;APOA2;HDAC4;HDAC1;TP73;ABCB1;APOA1 23129:[DB00027 DB06837] DB00027|Gramicidin D ABCB1 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways 23130:[DB00027 DB07962] DB00027|Gramicidin D ABCB1 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways GO:0006810| transport ABCB1;TTR 23131:[DB00027 DB03861] DB00027|Gramicidin D ABCB1 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways 23132:[DB00027 DB07714] DB00027|Gramicidin D ABCB1 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways 23133:[DB00027 DB01966] DB00027|Gramicidin D ABCB1 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways 23134:[DB00027 DB04816] DB00027|Gramicidin D ABCB1 DB04816|Dantron ALB common genes common pathways 23135:[DB00027 DB05076] DB00027|Gramicidin D ABCB1 DB05076|Fenretinide RBP4 common genes common pathways 23136:[DB00027 DB01698] DB00027|Gramicidin D ABCB1 DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways 23137:[DB00027 DB03994] DB00027|Gramicidin D ABCB1 DB03994|Ethanolamine ANXA3 common genes common pathways 23138:[DB00027 DB04400] DB00027|Gramicidin D ABCB1 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0042493| response to drug ABCB1;TH 23139:[DB00027 DB01791] DB00027|Gramicidin D ABCB1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways 23140:[DB00027 DB00896] DB00027|Gramicidin D ABCB1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways 23141:[DB00027 DB04594] DB00027|Gramicidin D ABCB1 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways 23142:[DB00027 DB00967] DB00027|Gramicidin D ABCB1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;CYP1A2 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 23143:[DB00027 DB06789] DB00027|Gramicidin D ABCB1 DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways 23144:[DB00027 DB03645] DB00027|Gramicidin D ABCB1 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways GO:0042493| response to drug ENO3;ABCB1 23145:[DB00027 DB02581] DB00027|Gramicidin D ABCB1 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways 23146:[DB00027 DB00584] DB00027|Gramicidin D ABCB1 DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC22A6;SLC22A7;SLC22A8;SLCO1A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport SLC15A1;ABCB1 GO:0042493| response to drug ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 23147:[DB00027 DB00485] DB00027|Gramicidin D ABCB1 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC15A2 23148:[DB00027 DB06599] DB00027|Gramicidin D ABCB1 DB06599|Lexatumumab TNFRSF10B common genes common pathways 23149:[DB00027 DB05471] DB00027|Gramicidin D ABCB1 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways 23150:[DB00027 DB06870] DB00027|Gramicidin D ABCB1 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways GO:0006810| transport ABCB1;AR 23151:[DB00027 DB07395] DB00027|Gramicidin D ABCB1 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways 23152:[DB00027 DB08119] DB00027|Gramicidin D ABCB1 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 23153:[DB00027 DB07072] DB00027|Gramicidin D ABCB1 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways 23154:[DB00027 DB06705] DB00027|Gramicidin D ABCB1 DB06705|Gadofosveset trisodium ALB common genes common pathways 23155:[DB00027 DB01640] DB00027|Gramicidin D ABCB1 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways 23156:[DB00027 DB00520] DB00027|Gramicidin D ABCB1 DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0042908| xenobiotic transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1;SLC22A1;SLC22A6 GO:0006810| transport ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1 GO:1901529| ABCB1 23157:[DB00027 DB05708] DB00027|Gramicidin D ABCB1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;CYP2E1 23158:[DB00027 DB08843] DB00027|Gramicidin D ABCB1 DB08843|GS 0573 SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 23159:[DB00027 DB00383] DB00027|Gramicidin D ABCB1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways 23160:[DB00027 DB07613] DB00027|Gramicidin D ABCB1 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways 23161:[DB00027 DB06849] DB00027|Gramicidin D ABCB1 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways 23162:[DB00027 DB00616] DB00027|Gramicidin D ABCB1 DB00616|Candoxatril MME;ACE common genes common pathways 23163:[DB00027 DB00180] DB00027|Gramicidin D ABCB1 DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways 23164:[DB00027 DB08960] DB00027|Gramicidin D ABCB1 DB08960|Hexamethonium CHRNA2 common genes common pathways 23165:[DB00027 DB06147] DB00027|Gramicidin D ABCB1 DB06147|Sulfathiazole CYP19A1 common genes common pathways 23166:[DB00027 DB06716] DB00027|Gramicidin D ABCB1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0006810| transport ABCB1;GABRB2;GABRB3 23167:[DB00027 DB01662] DB00027|Gramicidin D ABCB1 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways 23168:[DB00027 DB07350] DB00027|Gramicidin D ABCB1 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways 23169:[DB00027 DB07849] DB00027|Gramicidin D ABCB1 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways 23170:[DB00027 DB12515] DB00027|Gramicidin D ABCB1 DB12515|9-aminocamptothecin CYP3A4 common genes common pathways 23171:[DB00027 DB01497] DB00027|Gramicidin D ABCB1 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways 23172:[DB00027 DB07007] DB00027|Gramicidin D ABCB1 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways 23173:[DB00027 DB09536] DB00027|Gramicidin D ABCB1 DB09536|Titanium dioxide MARCO common genes common pathways 23174:[DB00027 DB05253] DB00027|Gramicidin D ABCB1 DB05253|Proellex PGR common genes common pathways 23175:[DB00027 DB04418] DB00027|Gramicidin D ABCB1 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways 23176:[DB00027 DB00259] DB00027|Gramicidin D ABCB1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 23177:[DB00027 DB00306] DB00027|Gramicidin D ABCB1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRB3;GABRA4;GABRA6;GRIK2;GABRA1;GABRB1;GABRG2;ABCB1;GABRD;GABRB2;GABRA5;GABRA3 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0042493| response to drug GABRG3;ABCB1 23178:[DB00027 DB00288] DB00027|Gramicidin D ABCB1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;ANXA1 23179:[DB00027 DB00156] DB00027|Gramicidin D ABCB1 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 23180:[DB00027 DB04975] DB00027|Gramicidin D ABCB1 DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 23181:[DB00027 DB13503] DB00027|Gramicidin D ABCB1 DB13503|Tyrothricin ACHE common genes common pathways 23182:[DB00027 DB03124] DB00027|Gramicidin D ABCB1 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways GO:0042493| response to drug ABCB1;CASP3 23183:[DB00027 DB00636] DB00027|Gramicidin D ABCB1 DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A1;ABCB1 23184:[DB00027 DB08626] DB00027|Gramicidin D ABCB1 DB08626|Thiorphan MME common genes common pathways 23185:[DB00027 DB05115] DB00027|Gramicidin D ABCB1 DB05115|NN344 INSR common genes common pathways 23186:[DB00027 DB06042] DB00027|Gramicidin D ABCB1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1;TUBB4A 23187:[DB00027 DB14724] DB00027|Gramicidin D ABCB1 DB14724|Emapalumab IFNG common genes common pathways 23188:[DB00027 DB03425] DB00027|Gramicidin D ABCB1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways GO:0006810| transport ABCB1;GRIK2 GO:0055085| transmembrane transport GRIK2;ABCB1 23189:[DB00027 DB08060] DB00027|Gramicidin D ABCB1 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways 23190:[DB00027 DB01742] DB00027|Gramicidin D ABCB1 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways 23191:[DB00027 DB00750] DB00027|Gramicidin D ABCB1 DB00750|Prilocaine SCN5A common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCB1 23192:[DB00027 DB05849] DB00027|Gramicidin D ABCB1 DB05849|NCX 950 ADRB2 common genes common pathways 23193:[DB00027 DB03470] DB00027|Gramicidin D ABCB1 DB03470|Trypanothione TPR common genes common pathways 23194:[DB00027 DB04445] DB00027|Gramicidin D ABCB1 DB04445|Mercuric iodide SULT2A1 common genes common pathways 23195:[DB00027 DB04133] DB00027|Gramicidin D ABCB1 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1;SLC22A5;SLC22A8;SLC22A11 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 23196:[DB00027 DB04934] DB00027|Gramicidin D ABCB1 DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways 23197:[DB00027 DB00751] DB00027|Gramicidin D ABCB1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug HTR2A;ADRA1A;ABCB1 23198:[DB00027 DB09232] DB00027|Gramicidin D ABCB1 DB09232|Cilnidipine CACNA1B;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0006810| transport CACNA1B;CACNB4;CACNB3;CACNB1;ABCB1 GO:0055085| transmembrane transport CACNA1S;ABCB1;CACNA1F;CACNA1B;CACNA1D;CACNA1C 23199:[DB00027 DB00621] DB00027|Gramicidin D ABCB1 DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0006810| transport ABCB1;AR 23200:[DB00027 DB08972] DB00027|Gramicidin D ABCB1 DB08972|Flumequine CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23201:[DB00027 DB00765] DB00027|Gramicidin D ABCB1 DB00765|Metyrosine TH common genes common pathways GO:0042493| response to drug ABCB1;TH 23202:[DB00027 DB05824] DB00027|Gramicidin D ABCB1 DB05824|CNS-5161 GRIN1 common genes common pathways 23203:[DB00027 DB01109] DB00027|Gramicidin D ABCB1 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0072089| stem cell proliferation FGF2;ABCB1 23204:[DB00027 DB03988] DB00027|Gramicidin D ABCB1 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways 23205:[DB00027 DB00805] DB00027|Gramicidin D ABCB1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0042493| response to drug HTR2C;HTR2B;DRD2;ABCB1;DRD1;SLC6A4;HTR2A 23206:[DB00027 DB11793] DB00027|Gramicidin D ABCB1 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways 23207:[DB00027 DB03316] DB00027|Gramicidin D ABCB1 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways 23208:[DB00027 DB06201] DB00027|Gramicidin D ABCB1 DB06201|Rufinamide GRM5;SCN9A;CES1;CYP2E1;CYP3A4;ALB common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN9A GO:0042493| response to drug CYP2E1;ABCB1 23209:[DB00027 DB06185] DB00027|Gramicidin D ABCB1 DB06185|Forodesine PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP 23210:[DB00027 DB01445] DB00027|Gramicidin D ABCB1 DB01445|Bufotenine MAOA;MAOB common genes common pathways GO:0042493| response to drug ABCB1;MAOB 23211:[DB00027 DB00374] DB00027|Gramicidin D ABCB1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways 23212:[DB00027 DB08445] DB00027|Gramicidin D ABCB1 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways 23213:[DB00027 DB05875] DB00027|Gramicidin D ABCB1 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;BCHE;PTGS2 23214:[DB00027 DB00958] DB00027|Gramicidin D ABCB1 DB00958|Carboplatin XDH;MPO;GSTT1;MT1A;MT2A;SOD1;GSTP1;GSTM1;NQO1;SLC31A1;SLC31A2;ATP7A;ATP7B;ABCG2;ABCC2 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCB1;SLC31A1 GO:0042493| response to drug SOD1;ABCB1;ABCG2;ABCC2 GO:0006810| transport ABCB1;ABCG2;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC2 23215:[DB00027 DB04880] DB00027|Gramicidin D ABCB1 DB04880|Enoximone PDE3A common genes common pathways GO:0042493| response to drug PDE3A;ABCB1 23216:[DB00027 DB12007] DB00027|Gramicidin D ABCB1 DB12007|Isoflavone PPARA;PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 23217:[DB00027 DB08801] DB00027|Gramicidin D ABCB1 DB08801|Dimetindene HRH1;CHRM2 common genes common pathways 23218:[DB00027 DB00947] DB00027|Gramicidin D ABCB1 DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 23219:[DB00027 DB06932] DB00027|Gramicidin D ABCB1 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways 23220:[DB00027 DB01762] DB00027|Gramicidin D ABCB1 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways GO:0055085| transmembrane transport SLC16A3;ABCB1;SLC5A8;SLC16A7;SLC16A1 23221:[DB00027 DB02089] DB00027|Gramicidin D ABCB1 DB02089|CP-526423 PYGL common genes common pathways 23222:[DB00027 DB01134] DB00027|Gramicidin D ABCB1 DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways 23223:[DB00027 DB00527] DB00027|Gramicidin D ABCB1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0055085| transmembrane transport SCN5A;CALM1;SCN10A;ABCB1 GO:0042493| response to drug BCHE;ABCB1 23224:[DB00027 DB00253] DB00027|Gramicidin D ABCB1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways 23225:[DB00027 DB05386] DB00027|Gramicidin D ABCB1 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE 23226:[DB00027 DB05429] DB00027|Gramicidin D ABCB1 DB05429|CAT-213 CCL11 common genes common pathways 23227:[DB00027 DB06127] DB00027|Gramicidin D ABCB1 DB06127|Bisegliptin DPP4 common genes common pathways 23228:[DB00027 DB09051] DB00027|Gramicidin D ABCB1 DB09051|Elosulfase alfa GALNS common genes common pathways 23229:[DB00027 DB06781] DB00027|Gramicidin D ABCB1 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways 23230:[DB00027 DB01615] DB00027|Gramicidin D ABCB1 DB01615|Aceprometazine HRH1 common genes common pathways 23231:[DB00027 DB00939] DB00027|Gramicidin D ABCB1 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLCO1C1;KCNQ2;KCNQ3 23232:[DB00027 DB02800] DB00027|Gramicidin D ABCB1 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways 23233:[DB00027 DB04931] DB00027|Gramicidin D ABCB1 DB04931|Afamelanotide MC1R common genes common pathways 23234:[DB00027 DB09151] DB00027|Gramicidin D ABCB1 DB09151|Flutemetamol (18F) APP common genes common pathways 23235:[DB00027 DB05945] DB00027|Gramicidin D ABCB1 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways 23236:[DB00027 DB07815] DB00027|Gramicidin D ABCB1 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways 23237:[DB00027 DB03478] DB00027|Gramicidin D ABCB1 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways 23238:[DB00027 DB01481] DB00027|Gramicidin D ABCB1 DB01481|1-Testosterone AR common genes common pathways GO:0006810| transport ABCB1;AR 23239:[DB00027 DB01892] DB00027|Gramicidin D ABCB1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0042493| response to drug ABCB1;ABCC2 GO:0006810| transport ABCC2;ABCB1 GO:0055085| transmembrane transport SLCO1B1;ABCB1;ABCC2 23240:[DB00027 DB06823] DB00027|Gramicidin D ABCB1 DB06823|Tiopronin MPO common genes common pathways 23241:[DB00027 DB00369] DB00027|Gramicidin D ABCB1 DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1 23242:[DB00027 DB01141] DB00027|Gramicidin D ABCB1 DB01141|Micafungin COMT;ARSA common genes common pathways GO:0042493| response to drug COMT;ABCB1 23243:[DB00027 DB06804] DB00027|Gramicidin D ABCB1 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 23244:[DB00027 DB00969] DB00027|Gramicidin D ABCB1 DB00969|Alosetron HTR3A;CYP2C9;CYP3A4;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1 23245:[DB00027 DB12131] DB00027|Gramicidin D ABCB1 DB12131|Vinpocetine CYP3A4 common genes common pathways 23246:[DB00027 DB00826] DB00027|Gramicidin D ABCB1 DB00826|Natamycin CYP3A4 common genes common pathways 23247:[DB00027 DB04820] DB00027|Gramicidin D ABCB1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0042493| response to drug ABCB1;MAOB;COMT 23248:[DB00027 DB07182] DB00027|Gramicidin D ABCB1 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 23249:[DB00027 DB02008] DB00027|Gramicidin D ABCB1 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 23250:[DB00027 DB06754] DB00027|Gramicidin D ABCB1 DB06754|Danaparoid SERPINC1 common genes common pathways 23251:[DB00027 DB13346] DB00027|Gramicidin D ABCB1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23252:[DB00027 DB11742] DB00027|Gramicidin D ABCB1 DB11742|Ebastine CYP3A4 common genes common pathways 23253:[DB00027 DB04920] DB00027|Gramicidin D ABCB1 DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE;ABCB1 GO:0055085| transmembrane transport CACNA1D;CACNA1C;CACNA1S;ABCB1;CACNA1F 23254:[DB00027 DB06742] DB00027|Gramicidin D ABCB1 DB06742|Ambroxol CYP3A4 common genes common pathways 23255:[DB00027 DB03546] DB00027|Gramicidin D ABCB1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 23256:[DB00027 DB00325] DB00027|Gramicidin D ABCB1 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1 23257:[DB00027 DB06218] DB00027|Gramicidin D ABCB1 DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways GO:0055085| transmembrane transport SCN3A;ABCB1;SCN10A;SCN9A 23258:[DB00027 DB00287] DB00027|Gramicidin D ABCB1 DB00287|Travoprost PTGFR common genes common pathways 23259:[DB00027 DB01006] DB00027|Gramicidin D ABCB1 DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways 23260:[DB00027 DB01378] DB00027|Gramicidin D ABCB1 DB01378|Magnesium cation ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1 23261:[DB00027 DB13931] DB00027|Gramicidin D ABCB1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways 23262:[DB00027 DB04837] DB00027|Gramicidin D ABCB1 DB04837|Clofedanol HRH1 common genes common pathways 23263:[DB00027 DB05161] DB00027|Gramicidin D ABCB1 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways 23264:[DB00027 DB00179] DB00027|Gramicidin D ABCB1 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways 23265:[DB00027 DB08950] DB00027|Gramicidin D ABCB1 DB08950|Indoramin ADRA1A common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 23266:[DB00027 DB07879] DB00027|Gramicidin D ABCB1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0042493| response to drug ABCB1;HDAC4 23267:[DB00027 DB07453] DB00027|Gramicidin D ABCB1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23268:[DB00027 DB02179] DB00027|Gramicidin D ABCB1 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 23269:[DB00027 DB03747] DB00027|Gramicidin D ABCB1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways 23270:[DB00027 DB06819] DB00027|Gramicidin D ABCB1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways 23271:[DB00027 DB07668] DB00027|Gramicidin D ABCB1 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways 23272:[DB00027 DB07383] DB00027|Gramicidin D ABCB1 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways 23273:[DB00027 DB05304] DB00027|Gramicidin D ABCB1 DB05304|WX-G250 CA9;IL2 common genes common pathways GO:0042493| response to drug ABCB1;CA9 23274:[DB00027 DB00419] DB00027|Gramicidin D ABCB1 DB00419|Miglustat UGCG common genes common pathways 23275:[DB00027 DB14528] DB00027|Gramicidin D ABCB1 DB14528|Chromium gluconate CYB5A;TF common genes common pathways 23276:[DB00027 DB01763] DB00027|Gramicidin D ABCB1 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways 23277:[DB00027 DB00155] DB00027|Gramicidin D ABCB1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0042493| response to drug OTC;ABCB1 GO:0055085| transmembrane transport SLC22A6;ABCB1 23278:[DB00027 DB08813] DB00027|Gramicidin D ABCB1 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0042493| response to drug ABCB1;MYC;FOS 23279:[DB00027 DB09082] DB00027|Gramicidin D ABCB1 DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways 23280:[DB00027 DB01091] DB00027|Gramicidin D ABCB1 DB01091|Butenafine SQLE common genes common pathways 23281:[DB00027 DB07003] DB00027|Gramicidin D ABCB1 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways 23282:[DB00027 DB00055] DB00027|Gramicidin D ABCB1 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways 23283:[DB00027 DB01359] DB00027|Gramicidin D ABCB1 DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0042493| response to drug HTR1B;ABCB1 23284:[DB00027 DB00281] DB00027|Gramicidin D ABCB1 DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1;CYP1A2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SCN5A;SCN9A;SLC22A5;ABCB1;SCN4A;SCN10A GO:0006810| transport ABCB1 23285:[DB00027 DB12340] DB00027|Gramicidin D ABCB1 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways GO:0042493| response to drug BCL2;BAD;ABCB1 GO:0055085| transmembrane transport BCL2;ABCB1 23286:[DB00027 DB04606] DB00027|Gramicidin D ABCB1 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways 23287:[DB00027 DB00524] DB00027|Gramicidin D ABCB1 DB00524|Metolazone SLC12A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC12A3 GO:0006810| transport ABCB1;SLC12A3 23288:[DB00027 DB04890] DB00027|Gramicidin D ABCB1 DB04890|Bepotastine HRH1 common genes common pathways 23289:[DB00027 DB07992] DB00027|Gramicidin D ABCB1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways 23290:[DB00027 DB03101] DB00027|Gramicidin D ABCB1 DB03101|Ribose-1-Phosphate PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1 23291:[DB00027 DB08055] DB00027|Gramicidin D ABCB1 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0042493| response to drug ABCB1;LCK 23292:[DB00027 DB04884] DB00027|Gramicidin D ABCB1 DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2C;HTR1B;ABCB1 23293:[DB00027 DB13981] DB00027|Gramicidin D ABCB1 DB13981|Nomegestrol acetate CYP3A4 common genes common pathways 23294:[DB00027 DB01776] DB00027|Gramicidin D ABCB1 DB01776|M-Cresol INS common genes common pathways 23295:[DB00027 DB09017] DB00027|Gramicidin D ABCB1 DB09017|Brotizolam CYP3A4 common genes common pathways 23296:[DB00027 DB09087] DB00027|Gramicidin D ABCB1 DB09087|Potassium alum ALB common genes common pathways 23297:[DB00027 DB09121] DB00027|Gramicidin D ABCB1 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug ABCB1;ADCY1 23298:[DB00027 DB07342] DB00027|Gramicidin D ABCB1 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways 23299:[DB00027 DB04377] DB00027|Gramicidin D ABCB1 DB04377|Meglutol HMGCR common genes common pathways 23300:[DB00027 DB08206] DB00027|Gramicidin D ABCB1 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways GO:0006810| transport TTR;ABCB1 23301:[DB00027 DB03010] DB00027|Gramicidin D ABCB1 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4A;TUBA4A;TUBA1A;TUBB;TUBB4B 23302:[DB00027 DB02147] DB00027|Gramicidin D ABCB1 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways 23303:[DB00027 DB04106] DB00027|Gramicidin D ABCB1 DB04106|Fotemustine TXNRD1 common genes common pathways 23304:[DB00027 DB00032] DB00027|Gramicidin D ABCB1 DB00032|Menotropins FSHR;LHCGR common genes common pathways 23305:[DB00027 DB00323] DB00027|Gramicidin D ABCB1 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;COMT 23306:[DB00027 DB00924] DB00027|Gramicidin D ABCB1 DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;CYP1A2;HTR2A 23307:[DB00027 DB11652] DB00027|Gramicidin D ABCB1 DB11652|Tucatinib ERBB2 common genes common pathways 23308:[DB00027 DB01591] DB00027|Gramicidin D ABCB1 DB01591|Solifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4 common genes common pathways 23309:[DB00027 DB08615] DB00027|Gramicidin D ABCB1 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways 23310:[DB00027 DB13158] DB00027|Gramicidin D ABCB1 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways 23311:[DB00027 DB02097] DB00027|Gramicidin D ABCB1 DB02097|Cytidine UCK2 common genes common pathways 23312:[DB00027 DB14042] DB00027|Gramicidin D ABCB1 DB14042|Galcanezumab CALCA;CALCB common genes common pathways 23313:[DB00027 DB05416] DB00027|Gramicidin D ABCB1 DB05416|Cardarine PPARD;PPARA common genes common pathways 23314:[DB00027 DB13914] DB00027|Gramicidin D ABCB1 DB13914|Volixibat SLC10A2 common genes common pathways GO:0006810| transport ABCB1;SLC10A2 GO:0055085| transmembrane transport SLC10A2;ABCB1 23315:[DB00027 DB03317] DB00027|Gramicidin D ABCB1 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways 23316:[DB00027 DB04027] DB00027|Gramicidin D ABCB1 DB04027|D-Arginine CKM common genes common pathways 23317:[DB00027 DB06433] DB00027|Gramicidin D ABCB1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways 23318:[DB00027 DB04516] DB00027|Gramicidin D ABCB1 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways 23319:[DB00027 DB00548] DB00027|Gramicidin D ABCB1 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0042493| response to drug SRD5A2;ABCB1 23320:[DB00027 DB06727] DB00027|Gramicidin D ABCB1 DB06727|Sparteine CYP2D6 common genes common pathways 23321:[DB00027 DB00406] DB00027|Gramicidin D ABCB1 DB00406|Gentian violet cation SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0055085| transmembrane transport SLC22A1;ABCB1 23322:[DB00027 DB09401] DB00027|Gramicidin D ABCB1 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0055085| transmembrane transport BCL2;ABCB1 GO:0042493| response to drug BCL2;ABCB1 23323:[DB00027 DB05309] DB00027|Gramicidin D ABCB1 DB05309|TP-508 FGF4 common genes common pathways 23324:[DB00027 DB03621] DB00027|Gramicidin D ABCB1 DB03621|L-709,587 FKBP1A common genes common pathways 23325:[DB00027 DB12212] DB00027|Gramicidin D ABCB1 DB12212|Landiolol CYP2D6 common genes common pathways 23326:[DB00027 DB05050] DB00027|Gramicidin D ABCB1 DB05050|ADL5859 OPRD1 common genes common pathways 23327:[DB00027 DB00929] DB00027|Gramicidin D ABCB1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways 23328:[DB00027 DB01270] DB00027|Gramicidin D ABCB1 DB01270|Ranibizumab VEGFA common genes common pathways 23329:[DB00027 DB00799] DB00027|Gramicidin D ABCB1 DB00799|Tazarotene RARA;RXRB;RARG;RARB;CYP2C8 common genes common pathways 23330:[DB00027 DB01581] DB00027|Gramicidin D ABCB1 DB01581|Sulfamerazine ALB common genes common pathways 23331:[DB00027 DB07246] DB00027|Gramicidin D ABCB1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 23332:[DB00027 DB13385] DB00027|Gramicidin D ABCB1 DB13385|Dihydroergocryptine CYP3A4 common genes common pathways 23333:[DB00027 DB08810] DB00027|Gramicidin D ABCB1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0042493| response to drug HTR2A;ABCB1 23334:[DB00027 DB09033] DB00027|Gramicidin D ABCB1 DB09033|Vedolizumab ITGA4;ITGB7 common genes common pathways 23335:[DB00027 DB01000] DB00027|Gramicidin D ABCB1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2;SLC22A5 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 23336:[DB00027 DB06154] DB00027|Gramicidin D ABCB1 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways 23337:[DB00027 DB00847] DB00027|Gramicidin D ABCB1 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0042493| response to drug ABCB1;SST 23338:[DB00027 DB07029] DB00027|Gramicidin D ABCB1 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways 23339:[DB00027 DB06939] DB00027|Gramicidin D ABCB1 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways 23340:[DB00027 DB06162] DB00027|Gramicidin D ABCB1 DB06162|Lumiliximab FCER2 common genes common pathways 23341:[DB00027 DB04270] DB00027|Gramicidin D ABCB1 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 23342:[DB00027 DB06268] DB00027|Gramicidin D ABCB1 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways 23343:[DB00027 DB06097] DB00027|Gramicidin D ABCB1 DB06097|GSK-923295 CENPE common genes common pathways 23344:[DB00027 DB09234] DB00027|Gramicidin D ABCB1 DB09234|Darodipine CYP3A4 common genes common pathways 23345:[DB00027 DB09459] DB00027|Gramicidin D ABCB1 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways 23346:[DB00027 DB05787] DB00027|Gramicidin D ABCB1 DB05787|LM-609 ITGB3 common genes common pathways 23347:[DB00027 DB08884] DB00027|Gramicidin D ABCB1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC3 GO:0042908| xenobiotic transport ABCB1;ABCC3 GO:0055085| transmembrane transport ABCC3;ABCB1;ABCC2;SLCO1B1;SLCO1B3;ABCC4 GO:0006810| transport ABCC2;ABCB1;ABCC3 GO:0042493| response to drug ABCC4;ABCB1;ABCC2 23348:[DB00027 DB12712] DB00027|Gramicidin D ABCB1 DB12712|Pilsicainide ABCB11 common genes common pathways GO:0006810| transport ABCB1;ABCB11 GO:0055085| transmembrane transport ABCB11;ABCB1 23349:[DB00027 DB12961] DB00027|Gramicidin D ABCB1 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways 23350:[DB00027 DB05458] DB00027|Gramicidin D ABCB1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways 23351:[DB00027 DB05109] DB00027|Gramicidin D ABCB1 DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 23352:[DB00027 DB01437] DB00027|Gramicidin D ABCB1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1 GO:0006810| transport GABRB3;GABRG2;GABRB1;GABRA1;GABRA6;GABRA4;ABCB1;GABRA5;GABRA3;GABRB2;GABRD 23353:[DB00027 DB06778] DB00027|Gramicidin D ABCB1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes common pathways GO:0042493| response to drug LOX;SOD1;ABCB1;MAOB 23354:[DB00027 DB01038] DB00027|Gramicidin D ABCB1 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways GO:0042493| response to drug DRD1;ABCB1;DRD2 23355:[DB00027 DB06204] DB00027|Gramicidin D ABCB1 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A4;ABCB1;SLC6A2 23356:[DB00027 DB09028] DB00027|Gramicidin D ABCB1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0006810| transport ABCB1;CHRNA6 23357:[DB00027 DB08234] DB00027|Gramicidin D ABCB1 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways 23358:[DB00027 DB00744] DB00027|Gramicidin D ABCB1 DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23359:[DB00027 DB05777] DB00027|Gramicidin D ABCB1 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways 23360:[DB00027 DB00452] DB00027|Gramicidin D ABCB1 DB00452|Framycetin rpsL;CXCR4 common genes common pathways 23361:[DB00027 DB03351] DB00027|Gramicidin D ABCB1 DB03351|Sri-9439 DHFR common genes common pathways 23362:[DB00027 DB00937] DB00027|Gramicidin D ABCB1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A3;SLC6A2 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A3;ABCB1;SLC6A2 23363:[DB00027 DB01199] DB00027|Gramicidin D ABCB1 DB01199|Tubocurarine CHRNA2;HTR3A;ACHE;CHRNA7;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0042493| response to drug BCHE;ABCB1 GO:0055085| transmembrane transport SLC22A1;SLC22A2;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCB1 23364:[DB00027 DB13191] DB00027|Gramicidin D ABCB1 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways GO:0006810| transport ABCB1;SLC6A8 GO:0055085| transmembrane transport SLC6A8;ABCB1 23365:[DB00027 DB09067] DB00027|Gramicidin D ABCB1 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways 23366:[DB00027 DB08605] DB00027|Gramicidin D ABCB1 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways 23367:[DB00027 DB05934] DB00027|Gramicidin D ABCB1 DB05934|CTCE-0214 CXCL12 common genes common pathways 23368:[DB00027 DB06186] DB00027|Gramicidin D ABCB1 DB06186|Ipilimumab CTLA4 common genes common pathways 23369:[DB00027 DB06408] DB00027|Gramicidin D ABCB1 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways 23370:[DB00027 DB00247] DB00027|Gramicidin D ABCB1 DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2A;HTR2C;HTR2B;HTR1B;ABCB1 23371:[DB00027 DB03515] DB00027|Gramicidin D ABCB1 DB03515|Equilenin CYP3A4 common genes common pathways 23372:[DB00027 DB05260] DB00027|Gramicidin D ABCB1 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways 23373:[DB00027 DB04977] DB00027|Gramicidin D ABCB1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 23374:[DB00027 DB01520] DB00027|Gramicidin D ABCB1 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways GO:0042493| response to drug ABCB1;GRIN2A GO:0006810| transport GRIN2C;ABCB1;GRIN2B;GRIN2A 23375:[DB00027 DB00724] DB00027|Gramicidin D ABCB1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways 23376:[DB00027 DB06271] DB00027|Gramicidin D ABCB1 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 23377:[DB00027 DB03467] DB00027|Gramicidin D ABCB1 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1;SLCO2B1;ABCG2 GO:0006810| transport ABCC1;ABCB1;ABCG2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;ABCG2;ABCC1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1 23378:[DB00027 DB02230] DB00027|Gramicidin D ABCB1 DB02230|Immucillin-G PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1 23379:[DB00027 DB00367] DB00027|Gramicidin D ABCB1 DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0006810| transport ABCB1;AR GO:0042493| response to drug ABCB1;SRD5A1 23380:[DB00027 DB00364] DB00027|Gramicidin D ABCB1 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways GO:0072089| stem cell proliferation FGF2;ABCB1 23381:[DB00027 DB07756] DB00027|Gramicidin D ABCB1 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways 23382:[DB00027 DB08612] DB00027|Gramicidin D ABCB1 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 23383:[DB00027 DB07142] DB00027|Gramicidin D ABCB1 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 23384:[DB00027 DB02888] DB00027|Gramicidin D ABCB1 DB02888|FKB-001 FKBP1A common genes common pathways 23385:[DB00027 DB03766] DB00027|Gramicidin D ABCB1 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways 23386:[DB00027 DB01624] DB00027|Gramicidin D ABCB1 DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;HTR2A;DRD2;ADRA1A;ABCB1 23387:[DB00027 DB03552] DB00027|Gramicidin D ABCB1 DB03552|3-Tyrosine TH common genes common pathways GO:0042493| response to drug TH;ABCB1 23388:[DB00027 DB02464] DB00027|Gramicidin D ABCB1 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways 23389:[DB00027 DB03585] DB00027|Gramicidin D ABCB1 DB03585|Oxyphenbutazone PLA2G2E;ALB;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 23390:[DB00027 DB08208] DB00027|Gramicidin D ABCB1 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways 23391:[DB00027 DB02468] DB00027|Gramicidin D ABCB1 DB02468|12-Phenylheme HMOX1 common genes common pathways 23392:[DB00027 DB00171] DB00027|Gramicidin D ABCB1 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1;ABCA1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCB1 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCC8;ABCA1;ABCC4;ABCC9;ABCC6;ABCC1;ACSL1;ABCC2;ABCB1;ADCY1 GO:0006810| transport ABCB11;ASNA1;SLC25A4;ABCC6;ABCC1;ABCB1;ABCC2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCC2;ABCB1;ABCC9;ABCG1;ABCC1;ABCC6;SLC25A4;CFTR;ABCC4;ABCB11;ABCC8;ABCA1 23393:[DB00027 DB05766] DB00027|Gramicidin D ABCB1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD2;ABCB1;DRD3 23394:[DB00027 DB00123] DB00027|Gramicidin D ABCB1 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways GO:0055085| transmembrane transport SLC16A10;SLC22A4;ABCB1 GO:0006810| transport SLC7A4;ABCB1;SLC7A1;SLC7A2 23395:[DB00027 DB08883] DB00027|Gramicidin D ABCB1 DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23396:[DB00027 DB00352] DB00027|Gramicidin D ABCB1 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0042493| response to drug ABCB1;ABCC4 GO:0055085| transmembrane transport ABCB1;ABCC4 23397:[DB00027 DB00445] DB00027|Gramicidin D ABCB1 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 23398:[DB00027 DB09066] DB00027|Gramicidin D ABCB1 DB09066|Corifollitropin alfa FSHR common genes common pathways 23399:[DB00027 DB03909] DB00027|Gramicidin D ABCB1 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways 23400:[DB00027 DB02152] DB00027|Gramicidin D ABCB1 DB02152|K-252a MET;MAP2K1 common genes common pathways 23401:[DB00027 DB06738] DB00027|Gramicidin D ABCB1 DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0006810| transport ABCB1;GRIN2C;GRIN2A;GRIN2B GO:0042493| response to drug GRIN2A;ABCB1 23402:[DB00027 DB04875] DB00027|Gramicidin D ABCB1 DB04875|Pralnacasan CASP1 common genes common pathways 23403:[DB00027 DB09215] DB00027|Gramicidin D ABCB1 DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 23404:[DB00027 DB08205] DB00027|Gramicidin D ABCB1 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways GO:0006810| transport ABCB1;TTR 23405:[DB00027 DB05223] DB00027|Gramicidin D ABCB1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0042493| response to drug HDAC2;ABCB1;HDAC1 23406:[DB00027 DB03788] DB00027|Gramicidin D ABCB1 DB03788|GC-24 THRB common genes common pathways 23407:[DB00027 DB02678] DB00027|Gramicidin D ABCB1 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways 23408:[DB00027 DB12698] DB00027|Gramicidin D ABCB1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways 23409:[DB00027 DB01597] DB00027|Gramicidin D ABCB1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 23410:[DB00027 DB04048] DB00027|Gramicidin D ABCB1 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways 23411:[DB00027 DB01709] DB00027|Gramicidin D ABCB1 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways GO:0042493| response to drug ENO3;ABCB1 23412:[DB00027 DB00031] DB00027|Gramicidin D ABCB1 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0042493| response to drug ABCB1;CALR 23413:[DB00027 DB00095] DB00027|Gramicidin D ABCB1 DB00095|Efalizumab ITGAL;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 23414:[DB00027 DB09526] DB00027|Gramicidin D ABCB1 DB09526|Hydroquinone TYR;ALB common genes common pathways 23415:[DB00027 DB07456] DB00027|Gramicidin D ABCB1 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways 23416:[DB00027 DB08467] DB00027|Gramicidin D ABCB1 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways 23417:[DB00027 DB00642] DB00027|Gramicidin D ABCB1 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;TYMS GO:0055085| transmembrane transport SLC22A8;ABCB1 23418:[DB00027 DB02187] DB00027|Gramicidin D ABCB1 DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways 23419:[DB00027 DB01207] DB00027|Gramicidin D ABCB1 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0042493| response to drug TBXA2R;ABCB1 23420:[DB00027 DB00043] DB00027|Gramicidin D ABCB1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways 23421:[DB00027 DB01194] DB00027|Gramicidin D ABCB1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 23422:[DB00027 DB09343] DB00027|Gramicidin D ABCB1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0055085| transmembrane transport SLC47A1;SLC22A2;ABCB1 GO:0006855| drug transmembrane transport SLC47A1;SLC22A2;ABCB1 23423:[DB00027 DB00974] DB00027|Gramicidin D ABCB1 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0042493| response to drug ABCB1;ADA 23424:[DB00027 DB00240] DB00027|Gramicidin D ABCB1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways 23425:[DB00027 DB05282] DB00027|Gramicidin D ABCB1 DB05282|MCC AIFM1 common genes common pathways 23426:[DB00027 DB00954] DB00027|Gramicidin D ABCB1 DB00954|Dirithromycin CYP3A4 common genes common pathways 23427:[DB00027 DB05249] DB00027|Gramicidin D ABCB1 DB05249|FavId CSF3R common genes common pathways 23428:[DB00027 DB08448] DB00027|Gramicidin D ABCB1 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways 23429:[DB00027 DB03690] DB00027|Gramicidin D ABCB1 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways 23430:[DB00027 DB02850] DB00027|Gramicidin D ABCB1 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways 23431:[DB00027 DB06600] DB00027|Gramicidin D ABCB1 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23432:[DB00027 DB06497] DB00027|Gramicidin D ABCB1 DB06497|Aplaviroc CCR5 common genes common pathways 23433:[DB00027 DB07717] DB00027|Gramicidin D ABCB1 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways GO:0006810| transport AR;ABCB1 23434:[DB00027 DB00846] DB00027|Gramicidin D ABCB1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways 23435:[DB00027 DB06209] DB00027|Gramicidin D ABCB1 DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes common pathways 23436:[DB00027 DB01125] DB00027|Gramicidin D ABCB1 DB01125|Anisindione GGCX common genes common pathways 23437:[DB00027 DB00748] DB00027|Gramicidin D ABCB1 DB00748|Carbinoxamine HRH1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 23438:[DB00027 DB01606] DB00027|Gramicidin D ABCB1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A8 23439:[DB00027 DB06909] DB00027|Gramicidin D ABCB1 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways 23440:[DB00027 DB00851] DB00027|Gramicidin D ABCB1 DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1;CYP1A1 23441:[DB00027 DB00481] DB00027|Gramicidin D ABCB1 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 23442:[DB00027 DB01009] DB00027|Gramicidin D ABCB1 DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A11;SLC22A7;ABCC4;SLC22A8;SLCO1A2 GO:0042493| response to drug PTGS2;ABCC4;UGT1A1;ABCB1 23443:[DB00027 DB01536] DB00027|Gramicidin D ABCB1 DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways 23444:[DB00027 DB12095] DB00027|Gramicidin D ABCB1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways 23445:[DB00027 DB08806] DB00027|Gramicidin D ABCB1 DB08806|Roxatidine acetate HRH2 common genes common pathways 23446:[DB00027 DB12498] DB00027|Gramicidin D ABCB1 DB12498|Mogamulizumab CXCR4 common genes common pathways 23447:[DB00027 DB00827] DB00027|Gramicidin D ABCB1 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0042493| response to drug CYP1A2;ABCB1 23448:[DB00027 DB11967] DB00027|Gramicidin D ABCB1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1 23449:[DB00027 DB00629] DB00027|Gramicidin D ABCB1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23450:[DB00027 DB01632] DB00027|Gramicidin D ABCB1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways 23451:[DB00027 DB00562] DB00027|Gramicidin D ABCB1 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways GO:0006810| transport SLC12A3;ABCB1 GO:0055085| transmembrane transport SLC12A3;ABCB1 GO:0042493| response to drug CA9;ABCB1 GO:2001225| regulation of chloride transport CA2;ABCB1 23452:[DB00027 DB02821] DB00027|Gramicidin D ABCB1 DB02821|Canaline OAT common genes common pathways 23453:[DB00027 DB05812] DB00027|Gramicidin D ABCB1 DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug CYP1A2;ABCB1;ABCC1 23454:[DB00027 DB01370] DB00027|Gramicidin D ABCB1 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 23455:[DB00027 DB04818] DB00027|Gramicidin D ABCB1 DB04818|Iproniazid MAOB;CYP2D6;CYP2C9 common genes common pathways GO:0042493| response to drug MAOB;ABCB1 23456:[DB00027 DB00889] DB00027|Gramicidin D ABCB1 DB00889|Granisetron HTR3A;CYP3A4;CYP1A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 23457:[DB00027 DB01114] DB00027|Gramicidin D ABCB1 DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A4;SLC22A1;SLC6A2;SLC6A3;SLC22A2;ABCB1 GO:0042493| response to drug SLC6A2;SLC6A3;ABCB1;SLC6A4 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2 23458:[DB00027 DB08905] DB00027|Gramicidin D ABCB1 DB08905|Formestane CYP3A4 common genes common pathways 23459:[DB00027 DB08800] DB00027|Gramicidin D ABCB1 DB08800|Chloropyramine HRH1 common genes common pathways 23460:[DB00027 DB07239] DB00027|Gramicidin D ABCB1 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways 23461:[DB00027 DB08384] DB00027|Gramicidin D ABCB1 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways 23462:[DB00027 DB05398] DB00027|Gramicidin D ABCB1 DB05398|C31G CD9 common genes common pathways 23463:[DB00027 DB00054] DB00027|Gramicidin D ABCB1 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways 23464:[DB00027 DB01277] DB00027|Gramicidin D ABCB1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways 23465:[DB00027 DB00461] DB00027|Gramicidin D ABCB1 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;CYP1A2 23466:[DB00027 DB02746] DB00027|Gramicidin D ABCB1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO2B1 GO:0042493| response to drug ABCB1;PPARG 23467:[DB00027 DB00892] DB00027|Gramicidin D ABCB1 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCB1 GO:0042493| response to drug ABCB1;BCHE 23468:[DB00027 DB02558] DB00027|Gramicidin D ABCB1 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways 23469:[DB00027 DB08530] DB00027|Gramicidin D ABCB1 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways 23470:[DB00027 DB13925] DB00027|Gramicidin D ABCB1 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways 23471:[DB00027 DB14060] DB00027|Gramicidin D ABCB1 DB14060|NS-398 PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23472:[DB00027 DB00005] DB00027|Gramicidin D ABCB1 DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0042493| response to drug ABCB1;LTA 23473:[DB00027 DB01180] DB00027|Gramicidin D ABCB1 DB01180|Rescinnamine ACE common genes common pathways 23474:[DB00027 DB00310] DB00027|Gramicidin D ABCB1 DB00310|Chlorthalidone SLC12A1 common genes common pathways GO:0055085| transmembrane transport SLC12A1;ABCB1 GO:0006810| transport ABCB1;SLC12A1 23475:[DB00027 DB00528] DB00027|Gramicidin D ABCB1 DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways GO:0006810| transport CACNG1;ABCB1 23476:[DB00027 DB12537] DB00027|Gramicidin D ABCB1 DB12537|Benzodiazepine CYP3A4 common genes common pathways 23477:[DB00027 DB02512] DB00027|Gramicidin D ABCB1 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways 23478:[DB00027 DB12589] DB00027|Gramicidin D ABCB1 DB12589|Dacetuzumab CD40 common genes common pathways 23479:[DB00027 DB01012] DB00027|Gramicidin D ABCB1 DB01012|Cinacalcet CASR;CYP3A4;CYP2D6;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23480:[DB00027 DB07106] DB00027|Gramicidin D ABCB1 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways 23481:[DB00027 DB09097] DB00027|Gramicidin D ABCB1 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;DRD1 23482:[DB00027 DB04886] DB00027|Gramicidin D ABCB1 DB04886|Calanolide A CYP3A4 common genes common pathways 23483:[DB00027 DB01132] DB00027|Gramicidin D ABCB1 DB01132|Pioglitazone PPARG;PPARD;PPARA;MAOB;CYP2C8;CYP3A4;PTGS1;CYP2C9;SLCO1B3;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;MAOB;PPARG GO:0055085| transmembrane transport ABCB1;SLCO1B1;SLCO1B3 23484:[DB00027 DB07615] DB00027|Gramicidin D ABCB1 DB07615|Tranilast HPGDS;CYP3A4;CYP2C9 common genes common pathways 23485:[DB00027 DB05075] DB00027|Gramicidin D ABCB1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways 23486:[DB00027 DB04736] DB00027|Gramicidin D ABCB1 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways 23487:[DB00027 DB05364] DB00027|Gramicidin D ABCB1 DB05364|ROX-888 CCL3 common genes common pathways 23488:[DB00027 DB05095] DB00027|Gramicidin D ABCB1 DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 23489:[DB00027 DB00067] DB00027|Gramicidin D ABCB1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0006810| transport ABCC2;ABCB1 GO:0042493| response to drug ABCC2;ABCB1 23490:[DB00027 DB00983] DB00027|Gramicidin D ABCB1 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways 23491:[DB00027 DB05204] DB00027|Gramicidin D ABCB1 DB05204|XL418 BTK common genes common pathways 23492:[DB00027 DB02902] DB00027|Gramicidin D ABCB1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways 23493:[DB00027 DB00789] DB00027|Gramicidin D ABCB1 DB00789|Gadopentetic acid PGD common genes common pathways 23494:[DB00027 DB07646] DB00027|Gramicidin D ABCB1 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 23495:[DB00027 DB04599] DB00027|Gramicidin D ABCB1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0006810| transport GRIA3;ABCB1 GO:0042493| response to drug HTR2A;DRD2;ABCB1 23496:[DB00027 DB01667] DB00027|Gramicidin D ABCB1 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;PNP;ABCB1 23497:[DB00027 DB00282] DB00027|Gramicidin D ABCB1 DB00282|Pamidronate FDPS common genes common pathways 23498:[DB00027 DB00935] DB00027|Gramicidin D ABCB1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 23499:[DB00027 DB05016] DB00027|Gramicidin D ABCB1 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;SLC22A8;ABCB1;SLC22A6 23500:[DB00027 DB01341] DB00027|Gramicidin D ABCB1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways GO:0006810| transport GABRA1;ABCB1 23501:[DB00027 DB02183] DB00027|Gramicidin D ABCB1 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways 23502:[DB00027 DB00129] DB00027|Gramicidin D ABCB1 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways GO:0006810| transport ABCB1;SLC7A1;SLC7A2;SLC7A4 GO:0042493| response to drug ABCB1;OTC;ARG1 23503:[DB00027 DB00763] DB00027|Gramicidin D ABCB1 DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;CYP2E1 23504:[DB00027 DB08868] DB00027|Gramicidin D ABCB1 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0042493| response to drug CYP2E1;HDAC1;ABCB1 23505:[DB00027 DB00519] DB00027|Gramicidin D ABCB1 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 23506:[DB00027 DB09274] DB00027|Gramicidin D ABCB1 DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways 23507:[DB00027 DB11919] DB00027|Gramicidin D ABCB1 DB11919|6-O-benzylguanine CYP3A4 common genes common pathways 23508:[DB00027 DB06928] DB00027|Gramicidin D ABCB1 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways 23509:[DB00027 DB11273] DB00027|Gramicidin D ABCB1 DB11273|Dihydroergocornine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2A;ADRA1A;HTR1B;ABCB1;HTR2B;HTR2C 23510:[DB00027 DB12248] DB00027|Gramicidin D ABCB1 DB12248|Tulobuterol ADRB2 common genes common pathways 23511:[DB00027 DB01084] DB00027|Gramicidin D ABCB1 DB01084|Emedastine HRH1 common genes common pathways 23512:[DB00027 DB11327] DB00027|Gramicidin D ABCB1 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23513:[DB00027 DB14542] DB00027|Gramicidin D ABCB1 DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCG2;ANXA1;HSD11B2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0055085| transmembrane transport SLCO1A2;SLC22A8;ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 23514:[DB00027 DB00626] DB00027|Gramicidin D ABCB1 DB00626|Bacitracin IDE;A2M common genes common pathways 23515:[DB00027 DB07288] DB00027|Gramicidin D ABCB1 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways 23516:[DB00027 DB02445] DB00027|Gramicidin D ABCB1 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 23517:[DB00027 DB00583] DB00027|Gramicidin D ABCB1 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC25A29;ABCB1;SLCO1B1;SLC22A8;SLC22A16;SLC22A5;SLC22A4 GO:0042493| response to drug ABCB1;CPT1A GO:0006855| drug transmembrane transport SLC22A5;ABCB1 23518:[DB00027 DB05212] DB00027|Gramicidin D ABCB1 DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways 23519:[DB00027 DB05944] DB00027|Gramicidin D ABCB1 DB05944|Varlitinib ERBB2;EGFR common genes common pathways 23520:[DB00027 DB05009] DB00027|Gramicidin D ABCB1 DB05009|Apadenoson ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;ABCB1 23521:[DB00027 DB12518] DB00027|Gramicidin D ABCB1 DB12518|Raclopride DRD2 common genes common pathways GO:0042493| response to drug ABCB1;DRD2 23522:[DB00027 DB05281] DB00027|Gramicidin D ABCB1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBA4A;ABCB1 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0042493| response to drug ABCB1;BCL2 23523:[DB00027 DB08391] DB00027|Gramicidin D ABCB1 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 23524:[DB00027 DB07775] DB00027|Gramicidin D ABCB1 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways GO:0006810| transport ABCB1;TTR 23525:[DB00027 DB06439] DB00027|Gramicidin D ABCB1 DB06439|Tyloxapol LPL common genes common pathways GO:0042493| response to drug LPL;ABCB1 23526:[DB00027 DB00158] DB00027|Gramicidin D ABCB1 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC3 GO:0006855| drug transmembrane transport ABCC3;ABCG2;ABCB1 GO:0006810| transport ABCC3;ABCG2;ABCB1 GO:0055085| transmembrane transport ABCC4;SLC46A1;ABCC3;SLC22A6;ABCC11;ABCB1;ABCG2 GO:0042493| response to drug ABCB1;ABCG2;ABCC4;GGH;MTHFR;CYP2E1 23527:[DB00027 DB12702] DB00027|Gramicidin D ABCB1 DB12702|Velusetrag HTR4 common genes common pathways 23528:[DB00027 DB03554] DB00027|Gramicidin D ABCB1 DB03554|5-Iodouracil DPYD common genes common pathways 23529:[DB00027 DB04356] DB00027|Gramicidin D ABCB1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23530:[DB00027 DB08056] DB00027|Gramicidin D ABCB1 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0042493| response to drug LCK;ABCB1 23531:[DB00027 DB00376] DB00027|Gramicidin D ABCB1 DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 23532:[DB00027 DB00901] DB00027|Gramicidin D ABCB1 DB00901|Bitolterol ADRB2 common genes common pathways 23533:[DB00027 DB00692] DB00027|Gramicidin D ABCB1 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 23534:[DB00027 DB07167] DB00027|Gramicidin D ABCB1 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways 23535:[DB00027 DB01041] DB00027|Gramicidin D ABCB1 DB01041|Thalidomide CRBN;TNF;NFKB1;FGFR2;PTGS2;ORM1;ORM2;CYP2C19;CYP1A1;CYP2E1;CYP2C9;PTGS1;PTGS2;CYP3A5 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1;PTGS2;CYP2E1 23536:[DB00027 DB01303] DB00027|Gramicidin D ABCB1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0042493| response to drug CYP1A2;HDAC2;PDE3A;ADORA2A;ABCB1 GO:0055085| transmembrane transport SLC22A7;ABCB1 23537:[DB00027 DB08341] DB00027|Gramicidin D ABCB1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0042493| response to drug PTK2B;ABCB1 23538:[DB00027 DB13627] DB00027|Gramicidin D ABCB1 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23539:[DB00027 DB05036] DB00027|Gramicidin D ABCB1 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways 23540:[DB00027 DB07969] DB00027|Gramicidin D ABCB1 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways 23541:[DB00027 DB04249] DB00027|Gramicidin D ABCB1 DB04249|Zinc Substituted Heme C CYCS common genes common pathways 23542:[DB00027 DB01890] DB00027|Gramicidin D ABCB1 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways 23543:[DB00027 DB00535] DB00027|Gramicidin D ABCB1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport SLC22A6;SLC15A1;ABCB1;SLC22A8;SLC22A5;SLC15A2 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 23544:[DB00027 DB05070] DB00027|Gramicidin D ABCB1 DB05070|ADX10059 GRM5 common genes common pathways 23545:[DB00027 DB05481] DB00027|Gramicidin D ABCB1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways 23546:[DB00027 DB13456] DB00027|Gramicidin D ABCB1 DB13456|Midecamycin CYP3A4 common genes common pathways 23547:[DB00027 DB14520] DB00027|Gramicidin D ABCB1 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:0042493| response to drug ABCB1;CALR 23548:[DB00027 DB04991] DB00027|Gramicidin D ABCB1 DB04991|XL784 ADAM10 common genes common pathways 23549:[DB00027 DB00723] DB00027|Gramicidin D ABCB1 DB00723|Methoxamine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 23550:[DB00027 DB11799] DB00027|Gramicidin D ABCB1 DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0055085| transmembrane transport SLC47A1;ABCB1 GO:0006855| drug transmembrane transport SLC47A1;ABCB1 23551:[DB00027 DB01424] DB00027|Gramicidin D ABCB1 DB01424|Aminophenazone CYP2C19;CYP1A2;CYP2C8;CYP2C9;CYP2D6;CYP3A4;CYP2C18;CYP17A1;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0042493| response to drug CYP1A2;ABCB1 23552:[DB00027 DB00025] DB00027|Gramicidin D ABCB1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0042493| response to drug ABCB1;CALR 23553:[DB00027 DB12329] DB00027|Gramicidin D ABCB1 DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways 23554:[DB00027 DB01365] DB00027|Gramicidin D ABCB1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 23555:[DB00027 DB01157] DB00027|Gramicidin D ABCB1 DB01157|Trimetrexate DHFR common genes common pathways 23556:[DB00027 DB09211] DB00027|Gramicidin D ABCB1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways 23557:[DB00027 DB01011] DB00027|Gramicidin D ABCB1 DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055085| transmembrane transport ABCC3;ABCB1 GO:0006810| transport ABCC3;ABCB1 GO:0006855| drug transmembrane transport ABCC3;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC3 23558:[DB00027 DB00219] DB00027|Gramicidin D ABCB1 DB00219|Oxyphenonium CHRM1 common genes common pathways 23559:[DB00027 DB13928] DB00027|Gramicidin D ABCB1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1B1 GO:0042493| response to drug ABCB1;LPL 23560:[DB00027 DB06771] DB00027|Gramicidin D ABCB1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23561:[DB00027 DB06800] DB00027|Gramicidin D ABCB1 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways 23562:[DB00027 DB13139] DB00027|Gramicidin D ABCB1 DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 23563:[DB00027 DB01152] DB00027|Gramicidin D ABCB1 DB01152|Candicidin CYP3A4 common genes common pathways 23564:[DB00027 DB00313] DB00027|Gramicidin D ABCB1 DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport SCN1A;SLC22A7;SCN5A;SCN7A;SLC16A1;SCN8A;SCN11A;SCN9A;SLC22A8;SLC22A5;SCN4A;ABCB1;SCN3A;SLCO2B1;SCN2A;SLC22A6;SCN10A GO:0042493| response to drug HDAC2;SCN11A;CYP1A2;ABAT;ABCB1;UGT1A1;PPARG GO:0006855| drug transmembrane transport ABCB1;SLC22A5 23565:[DB00027 DB00354] DB00027|Gramicidin D ABCB1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways 23566:[DB00027 DB04831] DB00027|Gramicidin D ABCB1 DB04831|Tienilic acid CYP2C9 common genes common pathways 23567:[DB00027 DB05399] DB00027|Gramicidin D ABCB1 DB05399|Succinobucol VCAM1 common genes common pathways 23568:[DB00027 DB00586] DB00027|Gramicidin D ABCB1 DB00586|Diclofenac PTGS2;PTGS1;ALOX5;SCN4A;ASIC1;KCNQ2;KCNQ3;PLA2G2A;CYP2C9;CYP2C19;CYP1A2;CYP2C8;UGT1A1;UGT2B7;PTGS1;CYP3A4;CYP1A1;CYP2B6;CYP2C18;CYP2E1;TTR;ALB;ABCC4;ABCB1;ABCC1;SLC22A6;SLC22A8;SLCO1C1;SLC22A11;SLCO1B1;ABCB11 common genes ABCB1 common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:1901529| ABCB1 GO:0042493| response to drug PTGS2;CYP1A2;CYP2E1;ABCC4;UGT1A1;ABCC1;CYP1A1;ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006810| transport ABCB11;ASIC1;TTR;ABCC1;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCC1;SLCO1C1;SLC22A6;ABCB1;SCN4A;SLC22A8;ABCB11;KCNQ3;SLCO1B1;ABCC4;SLC22A11;KCNQ2 23569:[DB00027 DB02698] DB00027|Gramicidin D ABCB1 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR 23570:[DB00027 DB02918] DB00027|Gramicidin D ABCB1 DB02918|Zardaverine PDE4D common genes common pathways 23571:[DB00027 DB14512] DB00027|Gramicidin D ABCB1 DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways 23572:[DB00027 DB01752] DB00027|Gramicidin D ABCB1 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways 23573:[DB00027 DB01970] DB00027|Gramicidin D ABCB1 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways 23574:[DB00027 DB07162] DB00027|Gramicidin D ABCB1 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways 23575:[DB00027 DB00185] DB00027|Gramicidin D ABCB1 DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways 23576:[DB00027 DB01419] DB00027|Gramicidin D ABCB1 DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23577:[DB00027 DB09123] DB00027|Gramicidin D ABCB1 DB09123|Dienogest PGR;AR;CYP3A4 common genes common pathways GO:0006810| transport AR;ABCB1 23578:[DB00027 DB00887] DB00027|Gramicidin D ABCB1 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0006810| transport SLC12A4;SLC10A1;ABCB1;SLC12A2;SLC12A1 GO:0055085| transmembrane transport ABCB1;SLC10A1;SLC12A5;SLC22A6;CFTR;SLC12A4;SLC12A1;SLC22A7;SLC22A11;SLC12A2;SLCO1A2;SLC22A8 GO:0042493| response to drug PTGS2;SLC12A5;ABCB1 23579:[DB00027 DB00756] DB00027|Gramicidin D ABCB1 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes common pathways 23580:[DB00027 DB09325] DB00027|Gramicidin D ABCB1 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 23581:[DB00027 DB00115] DB00027|Gramicidin D ABCB1 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0042493| response to drug ABCB1;MTHFR 23582:[DB00027 DB08257] DB00027|Gramicidin D ABCB1 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways 23583:[DB00027 DB07991] DB00027|Gramicidin D ABCB1 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways 23584:[DB00027 DB05298] DB00027|Gramicidin D ABCB1 DB05298|Tetomilast PDE4D common genes common pathways 23585:[DB00027 DB05562] DB00027|Gramicidin D ABCB1 DB05562|Naluzotan HTR1A common genes common pathways 23586:[DB00027 DB04339] DB00027|Gramicidin D ABCB1 DB04339|Carbocisteine GSTP1 common genes common pathways 23587:[DB00027 DB05101] DB00027|Gramicidin D ABCB1 DB05101|Matuzumab EGFR common genes common pathways 23588:[DB00027 DB06454] DB00027|Gramicidin D ABCB1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;DRD3 23589:[DB00027 DB08389] DB00027|Gramicidin D ABCB1 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 23590:[DB00027 DB00677] DB00027|Gramicidin D ABCB1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0042493| response to drug BCHE;ABCB1 23591:[DB00027 DB00136] DB00027|Gramicidin D ABCB1 DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways 23592:[DB00027 DB05806] DB00027|Gramicidin D ABCB1 DB05806|Cositecan TOP1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 23593:[DB00027 DB04633] DB00027|Gramicidin D ABCB1 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways 23594:[DB00027 DB13926] DB00027|Gramicidin D ABCB1 DB13926|Cenegermin NTRK1 common genes common pathways GO:0042493| response to drug ABCB1;NTRK1 23595:[DB00027 DB11323] DB00027|Gramicidin D ABCB1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 23596:[DB00027 DB03957] DB00027|Gramicidin D ABCB1 DB03957|SP2456 IL2 common genes common pathways 23597:[DB00027 DB14544] DB00027|Gramicidin D ABCB1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;ANXA1;ABCG2;HSD11B2 GO:0006810| transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1;SLC22A8;SLCO1A2 23598:[DB00027 DB14481] DB00027|Gramicidin D ABCB1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0006810| transport CACNB4;SLC20A2;SRI;SLC20A1;CACNA1I;ABCB1;CACNB1;CACNA1E;CACNB3 GO:0055085| transmembrane transport SLC20A1;CACNA1H;CALM1;SLC20A2;SLC34A3;SLC8A1;CACNA1D;CACNA1C;RYR1;TRPV6;CACNA1G;TRPV5;CACNA1S;CATSPER1;CACNA1E;RYR3;CACNA1A;ABCB1;CACNA1I;CACNA1F;SLC34A2;RYR2 GO:0042493| response to drug CALR;ABCB1;SLC8A1;SLC34A1 23599:[DB00027 DB08102] DB00027|Gramicidin D ABCB1 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways GO:0006810| transport ABCB1;TTR 23600:[DB00027 DB07020] DB00027|Gramicidin D ABCB1 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways 23601:[DB00027 DB05739] DB00027|Gramicidin D ABCB1 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways 23602:[DB00027 DB09308] DB00027|Gramicidin D ABCB1 DB09308|Solithromycin CYP3A4 common genes common pathways 23603:[DB00027 DB08927] DB00027|Gramicidin D ABCB1 DB08927|Amperozide HTR2A common genes common pathways GO:0042493| response to drug ABCB1;HTR2A 23604:[DB00027 DB05966] DB00027|Gramicidin D ABCB1 DB05966|TAS-108 ESR1;ESR2 common genes common pathways 23605:[DB00027 DB00017] DB00027|Gramicidin D ABCB1 DB00017|Salmon Calcitonin CALCR common genes common pathways 23606:[DB00027 DB04200] DB00027|Gramicidin D ABCB1 DB04200|Matairesinol DHRS4L2 common genes common pathways 23607:[DB00027 DB05266] DB00027|Gramicidin D ABCB1 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0042493| response to drug ABCB1;PDE3A 23608:[DB00027 DB13757] DB00027|Gramicidin D ABCB1 DB13757|Epanolol CYP2D6 common genes common pathways 23609:[DB00027 DB07306] DB00027|Gramicidin D ABCB1 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways 23610:[DB00027 DB01071] DB00027|Gramicidin D ABCB1 DB01071|Mequitazine HRH1;CYP2D6;CYP3A4 common genes common pathways 23611:[DB00027 DB01427] DB00027|Gramicidin D ABCB1 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0042493| response to drug ABCB1;PDE3A 23612:[DB00027 DB05229] DB00027|Gramicidin D ABCB1 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways 23613:[DB00027 DB05488] DB00027|Gramicidin D ABCB1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23614:[DB00027 DB14541] DB00027|Gramicidin D ABCB1 DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0006810| transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCG2;ABCB1 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;ANXA1;ABCG2;HSD11B2 23615:[DB00027 DB03577] DB00027|Gramicidin D ABCB1 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways 23616:[DB00027 DB06525] DB00027|Gramicidin D ABCB1 DB06525|Ganstigmine ACHE common genes common pathways 23617:[DB00027 DB00173] DB00027|Gramicidin D ABCB1 DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0042493| response to drug ACACB;ABCB1;UGT1A1 23618:[DB00027 DB00927] DB00027|Gramicidin D ABCB1 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A8 23619:[DB00027 DB09006] DB00027|Gramicidin D ABCB1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0042493| response to drug PPARG;ABCB1 23620:[DB00027 DB00979] DB00027|Gramicidin D ABCB1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE 23621:[DB00027 DB07577] DB00027|Gramicidin D ABCB1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug TYMS;ABCB1 23622:[DB00027 DB09318] DB00027|Gramicidin D ABCB1 DB09318|Synthetic Conjugated Estrogens, B ESR1;CYP3A4 common genes common pathways 23623:[DB00027 DB00928] DB00027|Gramicidin D ABCB1 DB00928|Azacitidine DNMT1;CDA common genes common pathways 23624:[DB00027 DB09369] DB00027|Gramicidin D ABCB1 DB09369|Polyestradiol phosphate ESR1 common genes common pathways 23625:[DB00027 DB08734] DB00027|Gramicidin D ABCB1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug ABCB1;TYMS 23626:[DB00027 DB09116] DB00027|Gramicidin D ABCB1 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0042493| response to drug CAT;ABCB1 23627:[DB00027 DB09347] DB00027|Gramicidin D ABCB1 DB09347|Acetrizoic acid ALB common genes common pathways 23628:[DB00027 DB05029] DB00027|Gramicidin D ABCB1 DB05029|Lancovutide PLA2G4A common genes common pathways 23629:[DB00027 DB00262] DB00027|Gramicidin D ABCB1 DB00262|Carmustine GSR;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23630:[DB00027 DB13520] DB00027|Gramicidin D ABCB1 DB13520|Metergoline SCN2A common genes common pathways GO:0055085| transmembrane transport SCN2A;ABCB1 23631:[DB00027 DB08369] DB00027|Gramicidin D ABCB1 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways 23632:[DB00027 DB05876] DB00027|Gramicidin D ABCB1 DB05876|PDE4 PDE4A common genes common pathways 23633:[DB00027 DB06441] DB00027|Gramicidin D ABCB1 DB06441|Cangrelor P2RY12 common genes common pathways 23634:[DB00027 DB02431] DB00027|Gramicidin D ABCB1 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways 23635:[DB00027 DB00601] DB00027|Gramicidin D ABCB1 DB00601|Linezolid MAOA;MAOB common genes common pathways GO:0042493| response to drug ABCB1;MAOB 23636:[DB00027 DB14019] DB00027|Gramicidin D ABCB1 DB14019|Fosnetupitant CYP3A4 common genes common pathways 23637:[DB00027 DB09059] DB00027|Gramicidin D ABCB1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0042493| response to drug ABCB1;OXTR 23638:[DB00027 DB08805] DB00027|Gramicidin D ABCB1 DB08805|Metiamide HRH2 common genes common pathways 23639:[DB00027 DB01454] DB00027|Gramicidin D ABCB1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0042493| response to drug HTR2C;HTR2B;SLC6A3;ABCB1;SLC6A2;SLC6A4;HTR2A GO:0055085| transmembrane transport SLC6A4;SLC18A2;ABCB1;SLC6A3;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 23640:[DB00027 DB00204] DB00027|Gramicidin D ABCB1 DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0055085| transmembrane transport SLC22A2;ABCB1;KCNH2 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 23641:[DB00027 DB05459] DB00027|Gramicidin D ABCB1 DB05459|Briakinumab IL12B;IL23A common genes common pathways 23642:[DB00027 DB13003] DB00027|Gramicidin D ABCB1 DB13003|Cortivazol NR3C1 common genes common pathways 23643:[DB00027 DB00914] DB00027|Gramicidin D ABCB1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;SLC22A2;ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2 23644:[DB00027 DB07221] DB00027|Gramicidin D ABCB1 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways 23645:[DB00027 DB01956] DB00027|Gramicidin D ABCB1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0042493| response to drug ABCB1;GABRG3 GO:0006810| transport GABRA5;GABRA3;SLC15A1;GABRB2;GABRD;ABCB1;GABRG2;GABRB1;SLC6A6;GABRA1;GABRA6;GABRA4;GRIN2B;GABRB3 GO:0055085| transmembrane transport SLC36A1;SLC15A1;ABCB1 23646:[DB00027 DB00469] DB00027|Gramicidin D ABCB1 DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 GO:0042493| response to drug ABCB1;PTGS2 23647:[DB00027 DB01780] DB00027|Gramicidin D ABCB1 DB01780|Fusicoccin YWHAE common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle YWHAE;ABCB1 23648:[DB00027 DB04465] DB00027|Gramicidin D ABCB1 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways 23649:[DB00027 DB01717] DB00027|Gramicidin D ABCB1 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways 23650:[DB00027 DB07181] DB00027|Gramicidin D ABCB1 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways 23651:[DB00027 DB12887] DB00027|Gramicidin D ABCB1 DB12887|Tazemetostat EZH2 common genes common pathways 23652:[DB00027 DB00620] DB00027|Gramicidin D ABCB1 DB00620|Triamcinolone NR3C1;CYP3A4;PTGS2;BCHE;SERPINA6 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;BCHE 23653:[DB00027 DB05744] DB00027|Gramicidin D ABCB1 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways GO:0042493| response to drug ABCB1;IL10 23654:[DB00027 DB08078] DB00027|Gramicidin D ABCB1 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways 23655:[DB00027 DB05867] DB00027|Gramicidin D ABCB1 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 23656:[DB00027 DB12228] DB00027|Gramicidin D ABCB1 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways 23657:[DB00027 DB00489] DB00027|Gramicidin D ABCB1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCB1 23658:[DB00027 DB01015] DB00027|Gramicidin D ABCB1 DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0006810| transport ABCB11;ABCB1 23659:[DB00027 DB05003] DB00027|Gramicidin D ABCB1 DB05003|Imexon RRM2;RRM1 common genes common pathways 23660:[DB00027 DB03667] DB00027|Gramicidin D ABCB1 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways 23661:[DB00027 DB00209] DB00027|Gramicidin D ABCB1 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways 23662:[DB00027 DB00730] DB00027|Gramicidin D ABCB1 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;CYP1A2 23663:[DB00027 DB01963] DB00027|Gramicidin D ABCB1 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways 23664:[DB00027 DB03359] DB00027|Gramicidin D ABCB1 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways 23665:[DB00027 DB04978] DB00027|Gramicidin D ABCB1 DB04978|SP1049C TOP2A common genes common pathways 23666:[DB00027 DB05205] DB00027|Gramicidin D ABCB1 DB05205|CX157 MAOA common genes common pathways 23667:[DB00027 DB00359] DB00027|Gramicidin D ABCB1 DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 23668:[DB00027 DB00673] DB00027|Gramicidin D ABCB1 DB00673|Aprepitant TACR1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9 common genes common pathways 23669:[DB00027 DB00761] DB00027|Gramicidin D ABCB1 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0042493| response to drug SLC12A5;ABCB1 GO:0006810| transport SLC12A7;SLC12A4;ABCB1;SLC12A2;SLC12A1 GO:0055085| transmembrane transport SLC12A6;SLC12A1;SLC12A2;ABCB1;SLC12A5;SLC12A7;SLC12A4 23670:[DB00027 DB01028] DB00027|Gramicidin D ABCB1 DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug MT-ND1;ABCB1;CYP2E1;CYP1A2;GABRG3 GO:0055085| transmembrane transport ABCB1;KCNA1 GO:0006810| transport GABRB3;GABRB1;GABRG2;GABRA1;GABRA4;GABRA6;ABCB1;GABRA5;GABRA3;GABRB2;GABRD 23671:[DB00027 DB04271] DB00027|Gramicidin D ABCB1 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 23672:[DB00027 DB11714] DB00027|Gramicidin D ABCB1 DB11714|Durvalumab CD274;CD80 common genes common pathways 23673:[DB00027 DB03753] DB00027|Gramicidin D ABCB1 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways 23674:[DB00027 DB14025] DB00027|Gramicidin D ABCB1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23675:[DB00027 DB14634] DB00027|Gramicidin D ABCB1 DB14634|Fluprednidene acetate CYP3A4 common genes common pathways 23676:[DB00027 DB08455] DB00027|Gramicidin D ABCB1 DB08455|Ro 12-7310 CRABP2 common genes common pathways 23677:[DB00027 DB02486] DB00027|Gramicidin D ABCB1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways 23678:[DB00027 DB06543] DB00027|Gramicidin D ABCB1 DB06543|Astaxanthin NFKBIA common genes common pathways 23679:[DB00027 DB06994] DB00027|Gramicidin D ABCB1 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways 23680:[DB00027 DB00154] DB00027|Gramicidin D ABCB1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23681:[DB00027 DB12278] DB00027|Gramicidin D ABCB1 DB12278|Propiverine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CACNA1C;ADRA1A;CYP3A4;FMO1;FMO3;CYP2B common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1 GO:0055085| transmembrane transport ABCB1;CACNA1C 23682:[DB00027 DB00221] DB00027|Gramicidin D ABCB1 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways 23683:[DB00027 DB05227] DB00027|Gramicidin D ABCB1 DB05227|APD791 HTR2A common genes common pathways GO:0042493| response to drug HTR2A;ABCB1 23684:[DB00027 DB08908] DB00027|Gramicidin D ABCB1 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0042493| response to drug RELA;ABCB1 23685:[DB00027 DB05104] DB00027|Gramicidin D ABCB1 DB05104|Asimadoline OPRK1 common genes common pathways 23686:[DB00027 DB09071] DB00027|Gramicidin D ABCB1 DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23687:[DB00027 DB05013] DB00027|Gramicidin D ABCB1 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways 23688:[DB00027 DB04803] DB00027|Gramicidin D ABCB1 DB04803|Verdoheme HMOX1 common genes common pathways 23689:[DB00027 DB00712] DB00027|Gramicidin D ABCB1 DB00712|Flurbiprofen PTGS1;PTGS2;CYP2C9;UGT2B7;UGT1A1;UGT1A3;UGT1A9;UGT2B4;ALB;ABCC4;SLC22A6 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;ABCC4;PTGS2 GO:0055085| transmembrane transport ABCC4;ABCB1;SLC22A6 23690:[DB00027 DB05706] DB00027|Gramicidin D ABCB1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways 23691:[DB00027 DB04487] DB00027|Gramicidin D ABCB1 DB04487|N-Methylleucine CXCL10 common genes common pathways 23692:[DB00027 DB08167] DB00027|Gramicidin D ABCB1 DB08167|Methylthioninium ACHE common genes common pathways 23693:[DB00027 DB11584] DB00027|Gramicidin D ABCB1 DB11584|Pipradrol DRD1;DRD5 common genes common pathways GO:0042493| response to drug DRD1;ABCB1 23694:[DB00027 DB02123] DB00027|Gramicidin D ABCB1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC10A1;SLC10A2;ABCB11;SLCO1A2 GO:0006810| transport SLC10A2;SLC10A1;ABCB1;ABCB11 23695:[DB00027 DB05890] DB00027|Gramicidin D ABCB1 DB05890|VEGF-AS VEGFA common genes common pathways 23696:[DB00027 DB07779] DB00027|Gramicidin D ABCB1 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways 23697:[DB00027 DB06335] DB00027|Gramicidin D ABCB1 DB06335|Saxagliptin DPP4;CYP3A4;CYP3A5;ABCC1;SLCO4C1;SLC22A8 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;SLCO4C1;ABCB1;SLC22A8 23698:[DB00027 DB12328] DB00027|Gramicidin D ABCB1 DB12328|Cantharidin AHR common genes common pathways 23699:[DB00027 DB08043] DB00027|Gramicidin D ABCB1 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways 23700:[DB00027 DB00817] DB00027|Gramicidin D ABCB1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23701:[DB00027 DB07623] DB00027|Gramicidin D ABCB1 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways 23702:[DB00027 DB07248] DB00027|Gramicidin D ABCB1 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways 23703:[DB00027 DB00900] DB00027|Gramicidin D ABCB1 DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes common pathways GO:0042493| response to drug ABCB1;PNP GO:0055085| transmembrane transport ABCB1;SLC22A6 23704:[DB00027 DB03951] DB00027|Gramicidin D ABCB1 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 23705:[DB00027 DB05319] DB00027|Gramicidin D ABCB1 DB05319|Oportuzumab monatox EPCAM common genes common pathways 23706:[DB00027 DB08804] DB00027|Gramicidin D ABCB1 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0006810| transport ABCB1;AR GO:0042493| response to drug MAOB;ABCB1 23707:[DB00027 DB00665] DB00027|Gramicidin D ABCB1 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0042493| response to drug ABCB1;POR GO:0006810| transport ABCB1;AR 23708:[DB00027 DB00246] DB00027|Gramicidin D ABCB1 DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0042493| response to drug DRD1;HTR2A;CYP1A2;HTR2C;DRD2;ADRA1A;ABCB1;HTR1B;DRD3 23709:[DB00027 DB00907] DB00027|Gramicidin D ABCB1 DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0042493| response to drug SLC6A4;SCN11A;ABCB1;SLC6A3;SLC6A2;BCHE GO:0055085| transmembrane transport SCN11A;SCN5A;SLC6A4;SCN10A;SLC6A2;SLC6A3;SLC22A2;ABCB1 GO:0006810| transport ABCB1;SLC6A2 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 23710:[DB00027 DB00605] DB00027|Gramicidin D ABCB1 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0042493| response to drug CYP1A1;ABCB1;PTGS2 23711:[DB00027 DB03796] DB00027|Gramicidin D ABCB1 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes common pathways GO:0042493| response to drug ABCB1;FABP3 23712:[DB00027 DB05187] DB00027|Gramicidin D ABCB1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 23713:[DB00027 DB05838] DB00027|Gramicidin D ABCB1 DB05838|OPC-51803 AVPR2 common genes common pathways 23714:[DB00027 DB03107] DB00027|Gramicidin D ABCB1 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 23715:[DB00027 DB01355] DB00027|Gramicidin D ABCB1 DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006810| transport ABCB1;GABRA3;GABRA5;GABRA1;GABRA4;GABRA6;GRIK2 GO:0042493| response to drug CYP2E1;ABCB1 23716:[DB00027 DB04454] DB00027|Gramicidin D ABCB1 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways 23717:[DB00027 DB00754] DB00027|Gramicidin D ABCB1 DB00754|Ethotoin SCN5A;NR1I2 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0055085| transmembrane transport SCN5A;ABCB1 23718:[DB00027 DB06080] DB00027|Gramicidin D ABCB1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways 23719:[DB00027 DB00651] DB00027|Gramicidin D ABCB1 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0042493| response to drug ABCB1;ADORA2A 23720:[DB00027 DB06230] DB00027|Gramicidin D ABCB1 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways 23721:[DB00027 DB06642] DB00027|Gramicidin D ABCB1 DB06642|Bevasiranib VEGFA common genes common pathways 23722:[DB00027 DB11182] DB00027|Gramicidin D ABCB1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways 23723:[DB00027 DB07482] DB00027|Gramicidin D ABCB1 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways 23724:[DB00027 DB04770] DB00027|Gramicidin D ABCB1 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways 23725:[DB00027 DB06813] DB00027|Gramicidin D ABCB1 DB06813|Pralatrexate DHFR;TYMS;FPGS;SLC19A1 common genes common pathways GO:0042493| response to drug ABCB1;TYMS 23726:[DB00027 DB08339] DB00027|Gramicidin D ABCB1 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways 23727:[DB00027 DB05069] DB00027|Gramicidin D ABCB1 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways 23728:[DB00027 DB14007] DB00027|Gramicidin D ABCB1 DB14007|Pentetic acid SERPINA1 common genes common pathways 23729:[DB00027 DB06229] DB00027|Gramicidin D ABCB1 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways GO:0042493| response to drug HTR2B;HTR2C;ABCB1;ADRA1A;DRD2;HTR2A 23730:[DB00027 DB05630] DB00027|Gramicidin D ABCB1 DB05630|Sodium stibogluconate TOP1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 23731:[DB00027 DB02527] DB00027|Gramicidin D ABCB1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0042493| response to drug ABCC4;ABCB1 GO:0006810| transport ABCC5;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle PRKAR2B;ABCB1 GO:0055085| transmembrane transport SLC22A6;ABCB1;ABCC11;ABCC5;HCN2;SLC22A8;ABCC4;SLC22A7 23732:[DB00027 DB09216] DB00027|Gramicidin D ABCB1 DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 23733:[DB00027 DB00820] DB00027|Gramicidin D ABCB1 DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways 23734:[DB00027 DB07954] DB00027|Gramicidin D ABCB1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways 23735:[DB00027 DB05168] DB00027|Gramicidin D ABCB1 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways 23736:[DB00027 DB00984] DB00027|Gramicidin D ABCB1 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0006810| transport ABCB1;AR 23737:[DB00027 DB11605] DB00027|Gramicidin D ABCB1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 23738:[DB00027 DB08602] DB00027|Gramicidin D ABCB1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways 23739:[DB00027 DB06728] DB00027|Gramicidin D ABCB1 DB06728|Aniline KLK1;ALB;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 23740:[DB00027 DB00522] DB00027|Gramicidin D ABCB1 DB00522|Bentiromide HPN common genes common pathways 23741:[DB00027 DB02004] DB00027|Gramicidin D ABCB1 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways 23742:[DB00027 DB00687] DB00027|Gramicidin D ABCB1 DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0006810| transport AR;ABCB1 23743:[DB00027 DB09301] DB00027|Gramicidin D ABCB1 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways 23744:[DB00027 DB05047] DB00027|Gramicidin D ABCB1 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways GO:0006810| transport GRIA4;ABCB1;GRIA3 23745:[DB00027 DB07614] DB00027|Gramicidin D ABCB1 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways 23746:[DB00027 DB00876] DB00027|Gramicidin D ABCB1 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0042493| response to drug ABCB1;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0006810| transport ABCB1;ABCC2 GO:0006855| drug transmembrane transport ABCB1;ABCC2 23747:[DB00027 DB01544] DB00027|Gramicidin D ABCB1 DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0006810| transport GABRB3;GABRA6;GABRA4;GABRA1;GABRG2;ABCB1;GABRA5;GABRA3 GO:0042493| response to drug UGT1A1;ABCB1;TSPO;CYP2E1 23748:[DB00027 DB05316] DB00027|Gramicidin D ABCB1 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0042493| response to drug HTR2A;ABCB1;DRD2 23749:[DB00027 DB05607] DB00027|Gramicidin D ABCB1 DB05607|PRX-08066 HTR2B common genes common pathways GO:0042493| response to drug ABCB1;HTR2B 23750:[DB00027 DB01414] DB00027|Gramicidin D ABCB1 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;ABCB1;SLC22A6 23751:[DB00027 DB03125] DB00027|Gramicidin D ABCB1 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways 23752:[DB00027 DB01192] DB00027|Gramicidin D ABCB1 DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways 23753:[DB00027 DB08861] DB00027|Gramicidin D ABCB1 DB08861|DPDPE SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCB1 23754:[DB00027 DB00339] DB00027|Gramicidin D ABCB1 DB00339|Pyrazinamide XDH;AOX1;CYP3A4 common genes common pathways 23755:[DB00027 DB04743] DB00027|Gramicidin D ABCB1 DB04743|Nimesulide PTGS2;PLA2G2E;LTF;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23756:[DB00027 DB04714] DB00027|Gramicidin D ABCB1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways 23757:[DB00027 DB09477] DB00027|Gramicidin D ABCB1 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways 23758:[DB00027 DB08795] DB00027|Gramicidin D ABCB1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport SLC22A5;SLC15A2;SLC15A1;ABCB1 23759:[DB00027 DB09240] DB00027|Gramicidin D ABCB1 DB09240|Niludipine CYP3A4 common genes common pathways 23760:[DB00027 DB13421] DB00027|Gramicidin D ABCB1 DB13421|Edoxudine ALB common genes common pathways 23761:[DB00027 DB12023] DB00027|Gramicidin D ABCB1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways 23762:[DB00027 DB05423] DB00027|Gramicidin D ABCB1 DB05423|ORG-34517 NR3C1 common genes common pathways 23763:[DB00027 DB05415] DB00027|Gramicidin D ABCB1 DB05415|OSI-461 PDE5A common genes common pathways 23764:[DB00027 DB06896] DB00027|Gramicidin D ABCB1 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways 23765:[DB00027 DB03981] DB00027|Gramicidin D ABCB1 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways GO:0072089| stem cell proliferation FGF2;ABCB1 23766:[DB00027 DB07968] DB00027|Gramicidin D ABCB1 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways 23767:[DB00027 DB03987] DB00027|Gramicidin D ABCB1 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways 23768:[DB00027 DB04076] DB00027|Gramicidin D ABCB1 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;PNP;CYP1A2 23769:[DB00027 DB06512] DB00027|Gramicidin D ABCB1 DB06512|Deramciclane HTR2A;HTR2C;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;HTR2C;HTR2A 23770:[DB00027 DB07403] DB00027|Gramicidin D ABCB1 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways 23771:[DB00027 DB05971] DB00027|Gramicidin D ABCB1 DB05971|Archexin AKT1 common genes common pathways 23772:[DB00027 DB12629] DB00027|Gramicidin D ABCB1 DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways 23773:[DB00027 DB00806] DB00027|Gramicidin D ABCB1 DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;ADORA2A;CYP1A2 23774:[DB00027 DB01273] DB00027|Gramicidin D ABCB1 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways GO:0055085| transmembrane transport SLC22A2;ABCB1 GO:0006810| transport CHRNA6;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 23775:[DB00027 DB08856] DB00027|Gramicidin D ABCB1 DB08856|DADLE SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;ABCB1 23776:[DB00027 DB07447] DB00027|Gramicidin D ABCB1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways 23777:[DB00027 DB08729] DB00027|Gramicidin D ABCB1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways 23778:[DB00027 DB09037] DB00027|Gramicidin D ABCB1 DB09037|Pembrolizumab PDCD1 common genes common pathways 23779:[DB00027 DB11752] DB00027|Gramicidin D ABCB1 DB11752|Bryostatin 1 CYP3A4 common genes common pathways 23780:[DB00027 DB08878] DB00027|Gramicidin D ABCB1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC46A1 23781:[DB00027 DB14146] DB00027|Gramicidin D ABCB1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:1901529| ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 23782:[DB00027 DB14029] DB00027|Gramicidin D ABCB1 DB14029|Furafylline CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23783:[DB00027 DB00808] DB00027|Gramicidin D ABCB1 DB00808|Indapamide SLC12A3;CYP3A4 common genes common pathways GO:0006810| transport ABCB1;SLC12A3 GO:0055085| transmembrane transport SLC12A3;ABCB1 23784:[DB00027 DB09107] DB00027|Gramicidin D ABCB1 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways 23785:[DB00027 DB03005] DB00027|Gramicidin D ABCB1 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 23786:[DB00027 DB00159] DB00027|Gramicidin D ABCB1 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0055085| transmembrane transport SLC8A1;TRPV1;ABCB1 GO:0006810| transport TRPV1;ABCB1 GO:0042493| response to drug PTGS2;SLC8A1;PPARG;ABCB1 23787:[DB00027 DB04903] DB00027|Gramicidin D ABCB1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways GO:0006810| transport GABRA3;ABCB1 23788:[DB00027 DB02831] DB00027|Gramicidin D ABCB1 DB02831|Dihydrogenphosphate DCXR common genes common pathways 23789:[DB00027 DB00649] DB00027|Gramicidin D ABCB1 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 23790:[DB00027 DB13200] DB00027|Gramicidin D ABCB1 DB13200|Lipegfilgrastim CSF3R common genes common pathways 23791:[DB00027 DB07406] DB00027|Gramicidin D ABCB1 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways 23792:[DB00027 DB00985] DB00027|Gramicidin D ABCB1 DB00985|Dimenhydrinate HRH1 common genes common pathways 23793:[DB00027 DB00727] DB00027|Gramicidin D ABCB1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways 23794:[DB00027 DB00785] DB00027|Gramicidin D ABCB1 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways 23795:[DB00027 DB13014] DB00027|Gramicidin D ABCB1 DB13014|Hypericin GSTA1;GSTP1;ALB common genes common pathways 23796:[DB00027 DB07369] DB00027|Gramicidin D ABCB1 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways 23797:[DB00027 DB00951] DB00027|Gramicidin D ABCB1 DB00951|Isoniazid katG;CYP2C8;CYP1A2;CYP3A4;CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2D6;CYP2C19;NAT2;CYP2A6;CYP2C8;ALB common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1 23798:[DB00027 DB00988] DB00027|Gramicidin D ABCB1 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A4;SLC22A5;SLC18A2;SLC22A3;SLC6A3;SLC22A2;ABCB1;SLC22A1;SLC6A2 GO:0042493| response to drug SLC6A3;DRD2;ABCB1;DRD3;COMT;MAOB;SLC6A2;SLC6A4;DRD1;SOD1 GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCB1;SLC22A5;SLC22A3 23799:[DB00027 DB00450] DB00027|Gramicidin D ABCB1 DB00450|Droperidol DRD2;ADRA1A common genes common pathways GO:0042493| response to drug DRD2;ADRA1A;ABCB1 23800:[DB00027 DB12742] DB00027|Gramicidin D ABCB1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0042493| response to drug ABCB1;RAD51;RET 23801:[DB00027 DB00433] DB00027|Gramicidin D ABCB1 DB00433|Prochlorperazine DRD2;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;DRD2 23802:[DB00027 DB02240] DB00027|Gramicidin D ABCB1 DB02240|Quinacrine mustard TPR common genes common pathways 23803:[DB00027 DB08240] DB00027|Gramicidin D ABCB1 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways 23804:[DB00027 DB11915] DB00027|Gramicidin D ABCB1 DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways 23805:[DB00027 DB06043] DB00027|Gramicidin D ABCB1 DB06043|Olaratumab PDGFRA common genes common pathways 23806:[DB00027 DB01579] DB00027|Gramicidin D ABCB1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0042493| response to drug ADRA1A;ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 23807:[DB00027 DB05964] DB00027|Gramicidin D ABCB1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0042493| response to drug SLC6A2;ABCB1;DRD2;SLC6A4 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 23808:[DB00027 DB05129] DB00027|Gramicidin D ABCB1 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways GO:0042493| response to drug ABCB1;TOP1 23809:[DB00027 DB06663] DB00027|Gramicidin D ABCB1 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways 23810:[DB00027 DB07753] DB00027|Gramicidin D ABCB1 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR 23811:[DB00027 DB00082] DB00027|Gramicidin D ABCB1 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0042493| response to drug BCHE;ABCB1 23812:[DB00027 DB01034] DB00027|Gramicidin D ABCB1 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways 23813:[DB00027 DB07555] DB00027|Gramicidin D ABCB1 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways 23814:[DB00027 DB07011] DB00027|Gramicidin D ABCB1 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways 23815:[DB00027 DB03867] DB00027|Gramicidin D ABCB1 DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways 23816:[DB00027 DB01861] DB00027|Gramicidin D ABCB1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 23817:[DB00027 DB09137] DB00027|Gramicidin D ABCB1 DB09137|Technetium Tc-99m mebrofenin SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1B1 23818:[DB00027 DB04557] DB00027|Gramicidin D ABCB1 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes common pathways GO:0055085| transmembrane transport SLCO2A1;ABCB1 23819:[DB00027 DB09300] DB00027|Gramicidin D ABCB1 DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways 23820:[DB00027 DB02082] DB00027|Gramicidin D ABCB1 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways 23821:[DB00027 DB05831] DB00027|Gramicidin D ABCB1 DB05831|ING-1 EPCAM common genes common pathways 23822:[DB00027 DB06995] DB00027|Gramicidin D ABCB1 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways 23823:[DB00027 DB07479] DB00027|Gramicidin D ABCB1 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways 23824:[DB00027 DB00870] DB00027|Gramicidin D ABCB1 DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1;PTGS2 23825:[DB00027 DB06199] DB00027|Gramicidin D ABCB1 DB06199|Atrasentan EDNRA common genes common pathways 23826:[DB00027 DB08130] DB00027|Gramicidin D ABCB1 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways 23827:[DB00027 DB00028] DB00027|Gramicidin D ABCB1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways 23828:[DB00027 DB04622] DB00027|Gramicidin D ABCB1 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways 23829:[DB00027 DB06196] DB00027|Gramicidin D ABCB1 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways 23830:[DB00027 DB01246] DB00027|Gramicidin D ABCB1 DB01246|Alimemazine HRH1;CYP3A4 common genes common pathways 23831:[DB00027 DB00366] DB00027|Gramicidin D ABCB1 DB00366|Doxylamine HRH1;CHRM1;NR1I3;CYP2B common genes common pathways 23832:[DB00027 DB01442] DB00027|Gramicidin D ABCB1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0042493| response to drug SLC6A2;MAOB;ABCB1;SLC6A3;HTR2A;SLC6A4 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A3;ABCB1;SLC6A2;SLC6A4;SLC18A2;SLC18A1 GO:0006855| drug transmembrane transport SLC18A1;ABCB1 23833:[DB00027 DB06900] DB00027|Gramicidin D ABCB1 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways 23834:[DB00027 DB00899] DB00027|Gramicidin D ABCB1 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways 23835:[DB00027 DB00218] DB00027|Gramicidin D ABCB1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23836:[DB00027 DB13530] DB00027|Gramicidin D ABCB1 DB13530|Mepindolol CYP2D6 common genes common pathways 23837:[DB00027 DB08842] DB00027|Gramicidin D ABCB1 DB08842|Acetylcarnitine SLC22A5 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A5 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 23838:[DB00027 DB03708] DB00027|Gramicidin D ABCB1 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways 23839:[DB00027 DB05199] DB00027|Gramicidin D ABCB1 DB05199|LX1031 TPH1 common genes common pathways 23840:[DB00027 DB05882] DB00027|Gramicidin D ABCB1 DB05882|CHF 4227 ESR1;ESR2 common genes common pathways 23841:[DB00027 DB08249] DB00027|Gramicidin D ABCB1 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0042493| response to drug ABCB1;DHODH 23842:[DB00027 DB13165] DB00027|Gramicidin D ABCB1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways 23843:[DB00027 DB03346] DB00027|Gramicidin D ABCB1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0006810| transport TTR;ABCB1 23844:[DB00027 DB00686] DB00027|Gramicidin D ABCB1 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0072089| stem cell proliferation ABCB1;FGF2 23845:[DB00027 DB07208] DB00027|Gramicidin D ABCB1 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 23846:[DB00027 DB09093] DB00027|Gramicidin D ABCB1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways 23847:[DB00027 DB07744] DB00027|Gramicidin D ABCB1 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways 23848:[DB00027 DB06203] DB00027|Gramicidin D ABCB1 DB06203|Alogliptin DPP4;CYP3A4;CYP2D6 common genes common pathways 23849:[DB00027 DB13443] DB00027|Gramicidin D ABCB1 DB13443|Esatenolol CYP2D6 common genes common pathways 23850:[DB00027 DB05642] DB00027|Gramicidin D ABCB1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A2;ABCB1 23851:[DB00027 DB08584] DB00027|Gramicidin D ABCB1 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways 23852:[DB00027 DB04859] DB00027|Gramicidin D ABCB1 DB04859|Zanapezil ACHE common genes common pathways 23853:[DB00027 DB00245] DB00027|Gramicidin D ABCB1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A3 GO:0055085| transmembrane transport ABCB1;SLC6A3 23854:[DB00027 DB07269] DB00027|Gramicidin D ABCB1 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 23855:[DB00027 DB00792] DB00027|Gramicidin D ABCB1 DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways 23856:[DB00027 DB07115] DB00027|Gramicidin D ABCB1 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 23857:[DB00027 DB03477] DB00027|Gramicidin D ABCB1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 23858:[DB00027 DB05295] DB00027|Gramicidin D ABCB1 DB05295|Eldecalcitol VDR common genes common pathways 23859:[DB00027 DB08566] DB00027|Gramicidin D ABCB1 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 23860:[DB00027 DB11156] DB00027|Gramicidin D ABCB1 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways 23861:[DB00027 DB08935] DB00027|Gramicidin D ABCB1 DB08935|Obinutuzumab MS4A1 common genes common pathways 23862:[DB00027 DB03878] DB00027|Gramicidin D ABCB1 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways 23863:[DB00027 DB05131] DB00027|Gramicidin D ABCB1 DB05131|TTP889 F9 common genes common pathways 23864:[DB00027 DB09257] DB00027|Gramicidin D ABCB1 DB09257|Gimeracil DPYD common genes common pathways 23865:[DB00027 DB07328] DB00027|Gramicidin D ABCB1 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways 23866:[DB00027 DB03434] DB00027|Gramicidin D ABCB1 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways 23867:[DB00027 DB00429] DB00027|Gramicidin D ABCB1 DB00429|Carboprost tromethamine PTGER1 common genes common pathways 23868:[DB00027 DB07899] DB00027|Gramicidin D ABCB1 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways 23869:[DB00027 DB09546] DB00027|Gramicidin D ABCB1 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A2;ABCB1 23870:[DB00027 DB08964] DB00027|Gramicidin D ABCB1 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways 23871:[DB00027 DB00981] DB00027|Gramicidin D ABCB1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways 23872:[DB00027 DB05507] DB00027|Gramicidin D ABCB1 DB05507|VX-765 CASP1;IL1B common genes common pathways 23873:[DB00027 DB01133] DB00027|Gramicidin D ABCB1 DB01133|Tiludronic acid ATP6V1A;PTPN1 common genes common pathways GO:0006810| transport ATP6V1A;ABCB1 23874:[DB00027 DB08879] DB00027|Gramicidin D ABCB1 DB08879|Belimumab TNFSF13B common genes common pathways 23875:[DB00027 DB02134] DB00027|Gramicidin D ABCB1 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 23876:[DB00027 DB07846] DB00027|Gramicidin D ABCB1 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways 23877:[DB00027 DB06550] DB00027|Gramicidin D ABCB1 DB06550|Bivatuzumab CD44 common genes common pathways 23878:[DB00027 DB05804] DB00027|Gramicidin D ABCB1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 GO:0055085| transmembrane transport SLCO1A2;SLCO1B3;SLCO1B1;ABCB11;SLC22A8;ABCB1;SLCO2B1;SLC10A6 GO:0006810| transport ABCB11;ABCB1 23879:[DB00027 DB04144] DB00027|Gramicidin D ABCB1 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways GO:0042493| response to drug ABCB1;MDM2 23880:[DB00027 DB07430] DB00027|Gramicidin D ABCB1 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways 23881:[DB00027 DB13074] DB00027|Gramicidin D ABCB1 DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways 23882:[DB00027 DB03639] DB00027|Gramicidin D ABCB1 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways 23883:[DB00027 DB11133] DB00027|Gramicidin D ABCB1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0042493| response to drug PPARG;ABCB1;SREBF1;PTGS2 23884:[DB00027 DB01325] DB00027|Gramicidin D ABCB1 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0055085| transmembrane transport SLC12A1;SLC12A3;SLC12A2;ABCB1 GO:0006810| transport SLC12A2;SLC12A1;SLC12A3;ABCB1 23885:[DB00027 DB01353] DB00027|Gramicidin D ABCB1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0006810| transport GABRA5;GABRA3;ABCB1;GABRA1;GABRA4;GABRA6;GRIK2 GO:0055085| transmembrane transport GRIK2;ABCB1 23886:[DB00027 DB04537] DB00027|Gramicidin D ABCB1 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways 23887:[DB00027 DB13934] DB00027|Gramicidin D ABCB1 DB13934|Ligandrol AR common genes common pathways GO:0006810| transport AR;ABCB1 23888:[DB00027 DB00230] DB00027|Gramicidin D ABCB1 DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CACNA1A 23889:[DB00027 DB04985] DB00027|Gramicidin D ABCB1 DB04985|Tigapotide RPSA common genes common pathways 23890:[DB00027 DB05141] DB00027|Gramicidin D ABCB1 DB05141|LY2181308 BIRC5 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;BIRC5 23891:[DB00027 DB00395] DB00027|Gramicidin D ABCB1 DB00395|Carisoprodol GABRA1;GABRB2;GABRG2;CYP2C19 common genes common pathways GO:0006810| transport GABRG2;GABRA1;GABRB2;ABCB1 23892:[DB00027 DB00058] DB00027|Gramicidin D ABCB1 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways 23893:[DB00027 DB12301] DB00027|Gramicidin D ABCB1 DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways 23894:[DB00027 DB04398] DB00027|Gramicidin D ABCB1 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A1;SLC16A7;SLC16A10;ABCB1;SLCO2B1;SLCO2A1;SLC16A3 23895:[DB00027 DB13174] DB00027|Gramicidin D ABCB1 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1;CYP1A2 23896:[DB00027 DB05099] DB00027|Gramicidin D ABCB1 DB05099|Ancrod FGA common genes common pathways 23897:[DB00027 DB11359] DB00027|Gramicidin D ABCB1 DB11359|Guaiacol ALB common genes common pathways 23898:[DB00027 DB07161] DB00027|Gramicidin D ABCB1 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways 23899:[DB00027 DB03677] DB00027|Gramicidin D ABCB1 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways 23900:[DB00027 DB11738] DB00027|Gramicidin D ABCB1 DB11738|Rilmenidine ADRA2A common genes common pathways 23901:[DB00027 DB08009] DB00027|Gramicidin D ABCB1 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways 23902:[DB00027 DB02530] DB00027|Gramicidin D ABCB1 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 23903:[DB00027 DB05879] DB00027|Gramicidin D ABCB1 DB05879|AME-527 TNF common genes common pathways 23904:[DB00027 DB11186] DB00027|Gramicidin D ABCB1 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 23905:[DB00027 DB08325] DB00027|Gramicidin D ABCB1 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways 23906:[DB00027 DB07449] DB00027|Gramicidin D ABCB1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 23907:[DB00027 DB01279] DB00027|Gramicidin D ABCB1 DB01279|Galsulfase PLIN3 common genes common pathways 23908:[DB00027 DB00391] DB00027|Gramicidin D ABCB1 DB00391|Sulpiride DRD2;DRD3;CA2;CA3;BCHE common genes common pathways GO:0042493| response to drug DRD3;BCHE;DRD2;ABCB1 GO:2001225| regulation of chloride transport ABCB1;CA2 23909:[DB00027 DB00388] DB00027|Gramicidin D ABCB1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ADRA1A;ABCB1 23910:[DB00027 DB07933] DB00027|Gramicidin D ABCB1 DB07933|Erteberel ESR2;ESR1 common genes common pathways 23911:[DB00027 DB00819] DB00027|Gramicidin D ABCB1 DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways GO:0042493| response to drug ABCB1;AQP1 GO:2001225| regulation of chloride transport CA2;ABCB1;CA7 GO:0055085| transmembrane transport AQP1;ABCB1;SLC22A6 23912:[DB00027 DB00284] DB00027|Gramicidin D ABCB1 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 23913:[DB00027 DB01067] DB00027|Gramicidin D ABCB1 DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC8;ABCB11 GO:0006810| transport ABCB1;ABCB11 GO:0042493| response to drug ABCC8;ABCB1;UGT1A1;PPARG 23914:[DB00027 DB01401] DB00027|Gramicidin D ABCB1 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 23915:[DB00027 DB01159] DB00027|Gramicidin D ABCB1 DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNMA1 GO:0006810| transport GABRG2;GABRB1;GABRA1;GABRA6;GABRA4;GRIN2A;GABRB3;GABRA3;GABRA5;GABRD;GABRB2;ABCB1 GO:0042493| response to drug KCNK3;ABCB1;MT-ND1;GABRG3;GRIN2A;CYP2E1 GO:0045332| phospholipid translocation ABCB1;KCNN4 23916:[DB00027 DB09085] DB00027|Gramicidin D ABCB1 DB09085|Tetracaine RYR1;RYR2 common genes common pathways GO:0055085| transmembrane transport ABCB1;RYR2;RYR1 23917:[DB00027 DB06560] DB00027|Gramicidin D ABCB1 DB06560|Pascolizumab IL4 common genes common pathways 23918:[DB00027 DB05367] DB00027|Gramicidin D ABCB1 DB05367|Actelion-1 EDNRA common genes common pathways 23919:[DB00027 DB01004] DB00027|Gramicidin D ABCB1 DB01004|Ganciclovir SLC22A1;SLC22A6;SLC22A8;SLC22A7;SLC47A1;SLC47A2 common genes common pathways GO:0006855| drug transmembrane transport SLC47A1;SLC47A2;ABCB1;SLC22A1 GO:0055085| transmembrane transport SLC47A2;SLC22A7;SLC47A1;SLC22A8;ABCB1;SLC22A6;SLC22A1 23920:[DB00027 DB00719] DB00027|Gramicidin D ABCB1 DB00719|Azatadine HRH1;CYP3A4 common genes common pathways 23921:[DB00027 DB08499] DB00027|Gramicidin D ABCB1 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways GO:0042493| response to drug ABCB1;CASP3 23922:[DB00027 DB01013] DB00027|Gramicidin D ABCB1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 23923:[DB00027 DB08880] DB00027|Gramicidin D ABCB1 DB08880|Teriflunomide DHODH;CYP2C8;CYP1A2;ABCG2;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCG2;ABCB1;SLCO1B1 GO:0006810| transport ABCG2;ABCB1 GO:0042493| response to drug DHODH;CYP1A2;ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 23924:[DB00027 DB00427] DB00027|Gramicidin D ABCB1 DB00427|Triprolidine HRH1 common genes common pathways 23925:[DB00027 DB12020] DB00027|Gramicidin D ABCB1 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 23926:[DB00027 DB06235] DB00027|Gramicidin D ABCB1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 23927:[DB00027 DB04971] DB00027|Gramicidin D ABCB1 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 23928:[DB00027 DB00703] DB00027|Gramicidin D ABCB1 DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:2001225| regulation of chloride transport ABCB1;CA2;CA7 GO:0042493| response to drug ABCB1;CYP2E1 23929:[DB00027 DB00337] DB00027|Gramicidin D ABCB1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways 23930:[DB00027 DB06470] DB00027|Gramicidin D ABCB1 DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0006810| transport ABCB1;GABRA1 23931:[DB00027 DB01340] DB00027|Gramicidin D ABCB1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1 GO:1901529| ABCB1 23932:[DB00027 DB01177] DB00027|Gramicidin D ABCB1 DB01177|Idarubicin TOP2A;CYP2C9;CYP2D6;ABCC1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 23933:[DB00027 DB05297] DB00027|Gramicidin D ABCB1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0055085| transmembrane transport ABCB1;BCL2 GO:0042493| response to drug ABCB1;BCL2 23934:[DB00027 DB03738] DB00027|Gramicidin D ABCB1 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 23935:[DB00027 DB00009] DB00027|Gramicidin D ABCB1 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 23936:[DB00027 DB08890] DB00027|Gramicidin D ABCB1 DB08890|Linaclotide GUCY2C common genes common pathways 23937:[DB00027 DB11134] DB00027|Gramicidin D ABCB1 DB11134|Cupric oxide ALB;CP common genes common pathways 23938:[DB00027 DB07285] DB00027|Gramicidin D ABCB1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 23939:[DB00027 DB03390] DB00027|Gramicidin D ABCB1 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways 23940:[DB00027 DB07419] DB00027|Gramicidin D ABCB1 DB07419|S-23 AR common genes common pathways GO:0006810| transport AR;ABCB1 23941:[DB00027 DB01628] DB00027|Gramicidin D ABCB1 DB01628|Etoricoxib PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;PTGS2;CYP1A2;ABCB1 23942:[DB00027 DB01001] DB00027|Gramicidin D ABCB1 DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways 23943:[DB00027 DB04689] DB00027|Gramicidin D ABCB1 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 23944:[DB00027 DB01002] DB00027|Gramicidin D ABCB1 DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN10A GO:0042493| response to drug CYP1A2;ABCB1 23945:[DB00027 DB04842] DB00027|Gramicidin D ABCB1 DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0006810| transport CACNG1;ABCB1 GO:0042493| response to drug HTR2A;DRD2;ABCB1 23946:[DB00027 DB04577] DB00027|Gramicidin D ABCB1 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways 23947:[DB00027 DB07069] DB00027|Gramicidin D ABCB1 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 23948:[DB00027 DB07728] DB00027|Gramicidin D ABCB1 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 23949:[DB00027 DB00509] DB00027|Gramicidin D ABCB1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0006810| transport SLC7A5;ABCB1 GO:0055085| transmembrane transport SLCO1C1;SLCO4C1;ABCB1;SLCO1B1;SLCO4A1 23950:[DB00027 DB11118] DB00027|Gramicidin D ABCB1 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways GO:0042493| response to drug ABCB1;CPS1 23951:[DB00027 DB01809] DB00027|Gramicidin D ABCB1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0042493| response to drug ABCB1;RET 23952:[DB00027 DB00833] DB00027|Gramicidin D ABCB1 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC22A8;ABCB11;SLC15A2 GO:0006810| transport SLC15A1;ABCB1;ABCB11;SLC15A2 23953:[DB00027 DB00591] DB00027|Gramicidin D ABCB1 DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0042493| response to drug ABCB1;ANXA1 23954:[DB00027 DB00554] DB00027|Gramicidin D ABCB1 DB00554|Piroxicam PTGS2;PTGS1;CYP2C9;CYP2C8;ALB;SLC22A6;SLC22A8;SLC22A11;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A11;SLC22A6;ABCB1;SLCO2B1 GO:0042493| response to drug PTGS2;ABCB1 23955:[DB00027 DB01549] DB00027|Gramicidin D ABCB1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0042493| response to drug DRD2;ABCB1 23956:[DB00027 DB06788] DB00027|Gramicidin D ABCB1 DB06788|Histrelin GNRHR common genes common pathways 23957:[DB00027 DB03612] DB00027|Gramicidin D ABCB1 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0042493| response to drug ABCB1;HADH 23958:[DB00027 DB05271] DB00027|Gramicidin D ABCB1 DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug DRD3;DRD2;ABCB1;DRD1 23959:[DB00027 DB02457] DB00027|Gramicidin D ABCB1 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways 23960:[DB00027 DB04057] DB00027|Gramicidin D ABCB1 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways 23961:[DB00027 DB08831] DB00027|Gramicidin D ABCB1 DB08831|2-deoxyglucose SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLC2A1;ABCB1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 23962:[DB00027 DB12323] DB00027|Gramicidin D ABCB1 DB12323|Radotinib ABL1 common genes common pathways 23963:[DB00027 DB01840] DB00027|Gramicidin D ABCB1 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways 23964:[DB00027 DB02358] DB00027|Gramicidin D ABCB1 DB02358|LY374571 MTHFD1 common genes common pathways 23965:[DB00027 DB04864] DB00027|Gramicidin D ABCB1 DB04864|Huperzine A ACHE common genes common pathways 23966:[DB00027 DB11693] DB00027|Gramicidin D ABCB1 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 23967:[DB00027 DB06834] DB00027|Gramicidin D ABCB1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways 23968:[DB00027 DB00161] DB00027|Gramicidin D ABCB1 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 23969:[DB00027 DB06612] DB00027|Gramicidin D ABCB1 DB06612|Mepolizumab IL5 common genes common pathways 23970:[DB00027 DB05152] DB00027|Gramicidin D ABCB1 DB05152|NGX267 CHRM1 common genes common pathways 23971:[DB00027 DB11529] DB00027|Gramicidin D ABCB1 DB11529|Melengestrol CYP3A4 common genes common pathways 23972:[DB00027 DB01931] DB00027|Gramicidin D ABCB1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways 23973:[DB00027 DB04954] DB00027|Gramicidin D ABCB1 DB04954|Tecadenoson ADORA1 common genes common pathways 23974:[DB00027 DB01189] DB00027|Gramicidin D ABCB1 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes common pathways GO:0042493| response to drug ABCB1;MT-ND1;GABRG3 GO:0006810| transport GABRB3;GABRB1;GABRG2;GABRA1;GABRA4;GABRA6;ABCB1;GABRA5;GABRA3;GABRB2;GABRD GO:0055085| transmembrane transport KCNA1;ABCB1 23975:[DB00027 DB05110] DB00027|Gramicidin D ABCB1 DB05110|VIR201 IFNG common genes common pathways 23976:[DB00027 DB04899] DB00027|Gramicidin D ABCB1 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways 23977:[DB00027 DB00432] DB00027|Gramicidin D ABCB1 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways GO:0042493| response to drug TYMS;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A6 23978:[DB00027 DB06194] DB00027|Gramicidin D ABCB1 DB06194|Elocalcitol VDR common genes common pathways 23979:[DB00027 DB12116] DB00027|Gramicidin D ABCB1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways 23980:[DB00027 DB02104] DB00027|Gramicidin D ABCB1 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways 23981:[DB00027 DB05846] DB00027|Gramicidin D ABCB1 DB05846|Mito-4509 APP common genes common pathways 23982:[DB00027 DB08802] DB00027|Gramicidin D ABCB1 DB08802|Isothipendyl HRH1 common genes common pathways 23983:[DB00027 DB02035] DB00027|Gramicidin D ABCB1 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways 23984:[DB00027 DB00307] DB00027|Gramicidin D ABCB1 DB00307|Bexarotene RXRA;RXRB;RXRG;CYP3A4;CYP2C9;CYP2C8 common genes common pathways 23985:[DB00027 DB13919] DB00027|Gramicidin D ABCB1 DB13919|Candesartan AGTR1;CYP2C8;CYP2C9;UGT1A3;PTGS1;ABCB1;SLCO1B1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1B1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 23986:[DB00027 DB04891] DB00027|Gramicidin D ABCB1 DB04891|Becocalcidiol MED1;VDR common genes common pathways 23987:[DB00027 DB00610] DB00027|Gramicidin D ABCB1 DB00610|Metaraminol ADRA1A common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 23988:[DB00027 DB02597] DB00027|Gramicidin D ABCB1 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways 23989:[DB00027 DB02309] DB00027|Gramicidin D ABCB1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 23990:[DB00027 DB13978] DB00027|Gramicidin D ABCB1 DB13978|Selisistat SIRT1 common genes common pathways 23991:[DB00027 DB02547] DB00027|Gramicidin D ABCB1 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 23992:[DB00027 DB06429] DB00027|Gramicidin D ABCB1 DB06429|Talnetant TACR3 common genes common pathways 23993:[DB00027 DB00731] DB00027|Gramicidin D ABCB1 DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport ABCC8;SLC15A2;SLC16A1;ABCC4;SLC15A1;SLC22A6;ABCB1 GO:0042493| response to drug ABCC8;ABCC4;PPARG;ABCB1 23994:[DB00027 DB04932] DB00027|Gramicidin D ABCB1 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0042493| response to drug ABCB1;ADORA2A 23995:[DB00027 DB00644] DB00027|Gramicidin D ABCB1 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways 23996:[DB00027 DB04927] DB00027|Gramicidin D ABCB1 DB04927|NM100060 SQLE common genes common pathways 23997:[DB00027 DB14543] DB00027|Gramicidin D ABCB1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;HSD11B2;ABCG2;ANXA1 GO:1901529| ABCB1 GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 23998:[DB00027 DB01221] DB00027|Gramicidin D ABCB1 DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0042493| response to drug HTR2A;HTR1B;ABCB1;DRD2;HTR2B;HTR2C;SLC6A2;BCHE GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A2 23999:[DB00027 DB07641] DB00027|Gramicidin D ABCB1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways 24000:[DB00027 DB04235] DB00027|Gramicidin D ABCB1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0042493| response to drug ABCB1;ABAT 24001:[DB00027 DB05541] DB00027|Gramicidin D ABCB1 DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0055085| transmembrane transport SCN8A;SCN11A;SCN9A;SCN1A;SCN7A;SCN5A;SV2A;SCN10A;ABCB1;SCN4A;SCN3A;SCN2A GO:0042493| response to drug ABCB1;SCN11A 24002:[DB00027 DB00389] DB00027|Gramicidin D ABCB1 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways 24003:[DB00027 DB01164] DB00027|Gramicidin D ABCB1 DB01164|Calcium Chloride S100A13 common genes common pathways 24004:[DB00027 DB06678] DB00027|Gramicidin D ABCB1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2B;HTR2C;ABCB1;HTR2A 24005:[DB00027 DB08703] DB00027|Gramicidin D ABCB1 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways 24006:[DB00027 DB09283] DB00027|Gramicidin D ABCB1 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0042493| response to drug ABCB1;PDE3A 24007:[DB00027 DB00740] DB00027|Gramicidin D ABCB1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0055085| transmembrane transport ABCB1;ABCG2;SCN5A GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;CYP1A2 24008:[DB00027 DB09317] DB00027|Gramicidin D ABCB1 DB09317|Synthetic Conjugated Estrogens, A ESR1;CYP3A4 common genes common pathways 24009:[DB00027 DB01482] DB00027|Gramicidin D ABCB1 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 24010:[DB00027 DB01297] DB00027|Gramicidin D ABCB1 DB01297|Practolol ADRB1;CYP2D6 common genes common pathways 24011:[DB00027 DB11772] DB00027|Gramicidin D ABCB1 DB11772|Pilaralisib PIK3CA common genes common pathways 24012:[DB00027 DB09568] DB00027|Gramicidin D ABCB1 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes common pathways GO:0042493| response to drug ABCB1;LPL;HADH 24013:[DB00027 DB00297] DB00027|Gramicidin D ABCB1 DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCB1 24014:[DB00027 DB11994] DB00027|Gramicidin D ABCB1 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1 24015:[DB00027 DB04841] DB00027|Gramicidin D ABCB1 DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;CYP1A2 GO:0006810| transport ABCB1;CACNA1I GO:0055085| transmembrane transport ABCB1;CACNA1I;CACNA1G;CALM1;CACNA1H 24016:[DB00027 DB05903] DB00027|Gramicidin D ABCB1 DB05903|KOS-1584 CYP3A4 common genes common pathways 24017:[DB00027 DB00491] DB00027|Gramicidin D ABCB1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 24018:[DB00027 DB04556] DB00027|Gramicidin D ABCB1 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways 24019:[DB00027 DB09008] DB00027|Gramicidin D ABCB1 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 24020:[DB00027 DB06436] DB00027|Gramicidin D ABCB1 DB06436|Semaxanib KDR;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 24021:[DB00027 DB00853] DB00027|Gramicidin D ABCB1 DB00853|Temozolomide CYP3A4 common genes common pathways 24022:[DB00027 DB04970] DB00027|Gramicidin D ABCB1 DB04970|Lesopitron HTR1A common genes common pathways 24023:[DB00027 DB06867] DB00027|Gramicidin D ABCB1 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways 24024:[DB00027 DB07412] DB00027|Gramicidin D ABCB1 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways 24025:[DB00027 DB01681] DB00027|Gramicidin D ABCB1 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways 24026:[DB00027 DB08492] DB00027|Gramicidin D ABCB1 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways 24027:[DB00027 DB01285] DB00027|Gramicidin D ABCB1 DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CRH 24028:[DB00027 DB00015] DB00027|Gramicidin D ABCB1 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 24029:[DB00027 DB08651] DB00027|Gramicidin D ABCB1 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways 24030:[DB00027 DB07271] DB00027|Gramicidin D ABCB1 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways 24031:[DB00027 DB00752] DB00027|Gramicidin D ABCB1 DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways GO:0042493| response to drug MAOB;ABCB1;CYP1A2;CYP2E1 24032:[DB00027 DB00231] DB00027|Gramicidin D ABCB1 DB00231|Temazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP3A4;CYP2B6;CYP2C8;CYP2C9 common genes common pathways GO:0006810| transport GABRG2;GABRB1;GABRA6;GABRR1;GABRA4;GABRA1;GABRB3;GABRR2;GABRA5;GABRA3;GABRB2;GABRD;ABCB1 GO:0042493| response to drug GABRG3;TSPO;ABCB1 24033:[DB00027 DB09013] DB00027|Gramicidin D ABCB1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways 24034:[DB00027 DB00277] DB00027|Gramicidin D ABCB1 DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A7 GO:0042493| response to drug PDE3A;CYP1A1;ADORA2A;ABCB1;CYP1A2;CYP2E1;ADA;HDAC2 24035:[DB00027 DB03181] DB00027|Gramicidin D ABCB1 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways 24036:[DB00027 DB09302] DB00027|Gramicidin D ABCB1 DB09302|Alirocumab PCSK9 common genes common pathways 24037:[DB00027 DB03906] DB00027|Gramicidin D ABCB1 DB03906|2-Phenylheme HMOX1 common genes common pathways 24038:[DB00027 DB13044] DB00027|Gramicidin D ABCB1 DB13044|Gossypol BCL2L1 common genes common pathways 24039:[DB00027 DB12789] DB00027|Gramicidin D ABCB1 DB12789|Dinoprost PTGDR2 common genes common pathways 24040:[DB00027 DB01852] DB00027|Gramicidin D ABCB1 DB01852|Kaempherol UGT3A1 common genes common pathways 24041:[DB00027 DB02235] DB00027|Gramicidin D ABCB1 DB02235|L-methionine (R)-S-oxide APP common genes common pathways 24042:[DB00027 DB03551] DB00027|Gramicidin D ABCB1 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways GO:0042493| response to drug ABCB1;PNP 24043:[DB00027 DB01175] DB00027|Gramicidin D ABCB1 DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A4;SLC6A3;ABCB1;SLC6A2 GO:0042493| response to drug SLC6A3;ABCB1;ADRA1A;SLC6A2;SLC6A4 24044:[DB00027 DB05073] DB00027|Gramicidin D ABCB1 DB05073|SRT501 SIRT1 common genes common pathways 24045:[DB00027 DB05010] DB00027|Gramicidin D ABCB1 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways 24046:[DB00027 DB01393] DB00027|Gramicidin D ABCB1 DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0042493| response to drug PPARG;CYP1A1;ABCB1 GO:0055085| transmembrane transport SLCO1B1;ABCB1 24047:[DB00027 DB00089] DB00027|Gramicidin D ABCB1 DB00089|Capromab pendetide FOLH1 common genes common pathways 24048:[DB00027 DB04583] DB00027|Gramicidin D ABCB1 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 24049:[DB00027 DB01675] DB00027|Gramicidin D ABCB1 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways 24050:[DB00027 DB00894] DB00027|Gramicidin D ABCB1 DB00894|Testolactone CYP19A1 common genes common pathways 24051:[DB00027 DB07457] DB00027|Gramicidin D ABCB1 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways 24052:[DB00027 DB07970] DB00027|Gramicidin D ABCB1 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways 24053:[DB00027 DB07051] DB00027|Gramicidin D ABCB1 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways 24054:[DB00027 DB08207] DB00027|Gramicidin D ABCB1 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways GO:0006810| transport TTR;ABCB1 24055:[DB00027 DB00086] DB00027|Gramicidin D ABCB1 DB00086|Streptokinase PLG;F2R;PLA2G4A common genes common pathways 24056:[DB00027 DB06795] DB00027|Gramicidin D ABCB1 DB06795|Mafenide CA6 common genes common pathways 24057:[DB00027 DB00447] DB00027|Gramicidin D ABCB1 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 24058:[DB00027 DB05854] DB00027|Gramicidin D ABCB1 DB05854|CLX-0921 PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 24059:[DB00027 DB00492] DB00027|Gramicidin D ABCB1 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 24060:[DB00027 DB00986] DB00027|Gramicidin D ABCB1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways 24061:[DB00027 DB05443] DB00027|Gramicidin D ABCB1 DB05443|ADL 10-0101 OPRK1 common genes common pathways 24062:[DB00027 DB05098] DB00027|Gramicidin D ABCB1 DB05098|Leptin LEPR common genes common pathways 24063:[DB00027 DB00217] DB00027|Gramicidin D ABCB1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways 24064:[DB00027 DB09101] DB00027|Gramicidin D ABCB1 DB09101|Elvitegravir pol;CYP3A4 common genes common pathways 24065:[DB00027 DB09344] DB00027|Gramicidin D ABCB1 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways GO:0055085| transmembrane transport SLC2A5;ABCB1;SLC2A2 24066:[DB00027 DB12202] DB00027|Gramicidin D ABCB1 DB12202|Zalutumumab EGFR common genes common pathways 24067:[DB00027 DB01281] DB00027|Gramicidin D ABCB1 DB01281|Abatacept CD80;CD86 common genes common pathways 24068:[DB00027 DB01090] DB00027|Gramicidin D ABCB1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 24069:[DB00027 DB12140] DB00027|Gramicidin D ABCB1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways 24070:[DB00027 DB08520] DB00027|Gramicidin D ABCB1 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways 24071:[DB00027 DB01291] DB00027|Gramicidin D ABCB1 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways 24072:[DB00027 DB02054] DB00027|Gramicidin D ABCB1 DB02054|Gabaculine OAT common genes common pathways 24073:[DB00027 DB09262] DB00027|Gramicidin D ABCB1 DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways 24074:[DB00027 DB01088] DB00027|Gramicidin D ABCB1 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0055085| transmembrane transport SLCO3A1;SLCO2A1;ABCB1;SLCO2B1 24075:[DB00027 DB02884] DB00027|Gramicidin D ABCB1 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways 24076:[DB00027 DB04845] DB00027|Gramicidin D ABCB1 DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways 24077:[DB00027 DB08575] DB00027|Gramicidin D ABCB1 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways 24078:[DB00027 DB02852] DB00027|Gramicidin D ABCB1 DB02852|Domoic Acid GRIK2 common genes common pathways GO:0006810| transport GRIK2;ABCB1 GO:0055085| transmembrane transport GRIK2;ABCB1 24079:[DB00027 DB06413] DB00027|Gramicidin D ABCB1 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0042493| response to drug ABCB1;SLC6A3;CYP1A2 24080:[DB00027 DB08085] DB00027|Gramicidin D ABCB1 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways 24081:[DB00027 DB08356] DB00027|Gramicidin D ABCB1 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways 24082:[DB00027 DB00544] DB00027|Gramicidin D ABCB1 DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCC3 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCC3 GO:0042493| response to drug PPAT;ABCC4;CYP1A2;MTHFR;ABCG2;ABCB1;TYMS GO:0006810| transport ABCB1;ABCG2;ABCC5;ABCC3 GO:0055085| transmembrane transport ABCB1;ABCC5;ABCG2;ABCC3;ABCC4;SLC22A7 24083:[DB00027 DB09149] DB00027|Gramicidin D ABCB1 DB09149|Florbetapir (18F) APP common genes common pathways 24084:[DB00027 DB00542] DB00027|Gramicidin D ABCB1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 GO:0042493| response to drug ABCB1;MTHFR 24085:[DB00027 DB12391] DB00027|Gramicidin D ABCB1 DB12391|Sagopilone CYP3A4 common genes common pathways 24086:[DB00027 DB13261] DB00027|Gramicidin D ABCB1 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 24087:[DB00027 DB01790] DB00027|Gramicidin D ABCB1 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways 24088:[DB00027 DB08565] DB00027|Gramicidin D ABCB1 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 24089:[DB00027 DB07749] DB00027|Gramicidin D ABCB1 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways 24090:[DB00027 DB01093] DB00027|Gramicidin D ABCB1 DB01093|Dimethyl sulfoxide CYP2C19;CYP2D6;CYP3A4;TTR common genes common pathways GO:0006810| transport TTR;ABCB1 24091:[DB00027 DB09120] DB00027|Gramicidin D ABCB1 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1 GO:0006810| transport ABCB1;TRPV1 GO:0055085| transmembrane transport TRPV1;ABCB1 24092:[DB00027 DB06116] DB00027|Gramicidin D ABCB1 DB06116|Eldelumab CXCL10 common genes common pathways 24093:[DB00027 DB05848] DB00027|Gramicidin D ABCB1 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways 24094:[DB00027 DB04036] DB00027|Gramicidin D ABCB1 DB04036|Coenzyme a Persulfide IVD common genes common pathways 24095:[DB00027 DB07240] DB00027|Gramicidin D ABCB1 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 24096:[DB00027 DB00143] DB00027|Gramicidin D ABCB1 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0006810| transport ABCC1;ABCC3;ABCB1;ABCC5;ABCC2 GO:0055085| transmembrane transport ABCC4;ABCC1;ABCC3;ABCB1;ABCC5;ABCC2 GO:0042493| response to drug ABCC4;MGST1;ABCC2;ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCC3;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1;ABCC3 24097:[DB00027 DB04834] DB00027|Gramicidin D ABCB1 DB04834|Rapacuronium CHRM2 common genes common pathways 24098:[DB00027 DB03176] DB00027|Gramicidin D ABCB1 DB03176|KB-141 THRB;THRA common genes common pathways 24099:[DB00027 DB01785] DB00027|Gramicidin D ABCB1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways 24100:[DB00027 DB14039] DB00027|Gramicidin D ABCB1 DB14039|Erenumab CALCRL common genes common pathways 24101:[DB00027 DB03683] DB00027|Gramicidin D ABCB1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 24102:[DB00027 DB03393] DB00027|Gramicidin D ABCB1 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways 24103:[DB00027 DB01025] DB00027|Gramicidin D ABCB1 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways 24104:[DB00027 DB03744] DB00027|Gramicidin D ABCB1 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways 24105:[DB00027 DB01613] DB00027|Gramicidin D ABCB1 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways 24106:[DB00027 DB01413] DB00027|Gramicidin D ABCB1 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport SLC15A2;SLC22A5;SLC15A1;ABCB1 24107:[DB00027 DB02016] DB00027|Gramicidin D ABCB1 DB02016|R048-8071 LSS common genes common pathways 24108:[DB00027 DB01878] DB00027|Gramicidin D ABCB1 DB01878|Benzophenone ESR1;ESR2 common genes common pathways 24109:[DB00027 DB03070] DB00027|Gramicidin D ABCB1 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways 24110:[DB00027 DB09212] DB00027|Gramicidin D ABCB1 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 24111:[DB00027 DB06089] DB00027|Gramicidin D ABCB1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNQ1;KCNQ4;KCNQ5;KCNQ2;KCNQ3 24112:[DB00027 DB00012] DB00027|Gramicidin D ABCB1 DB00012|Darbepoetin alfa EPOR common genes common pathways 24113:[DB00027 DB09119] DB00027|Gramicidin D ABCB1 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 24114:[DB00027 DB03929] DB00027|Gramicidin D ABCB1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0006810| transport ABCB1;SLC6A14 GO:0055085| transmembrane transport ABCB1;SLC6A14;SLC16A10 24115:[DB00027 DB08100] DB00027|Gramicidin D ABCB1 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0006810| transport ABCB1;TTR 24116:[DB00027 DB01685] DB00027|Gramicidin D ABCB1 DB01685|Topiroxostat XDH;CYP2C8;CYP2C9;CYP1A1;CYP3A4;CYP2C19;UGT1A9;ALB;ORM1;ABCG2;SLC22A8;SLC22A6 common genes common pathways GO:0042493| response to drug CYP1A1;ABCG2;ABCB1 GO:0055085| transmembrane transport SLC22A6;ABCB1;ABCG2;SLC22A8 GO:0006810| transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 24117:[DB00027 DB04924] DB00027|Gramicidin D ABCB1 DB04924|Itopride DRD2;ACHE common genes common pathways GO:0042493| response to drug ABCB1;DRD2 24118:[DB00027 DB00774] DB00027|Gramicidin D ABCB1 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0042493| response to drug ATP1A1;CA9;ABCB1 GO:0006810| transport ABCB1;SLC12A1 GO:0055085| transmembrane transport KCNMA1;SLC12A1;ABCB1 24119:[DB00027 DB04322] DB00027|Gramicidin D ABCB1 DB04322|LY249543 MTHFD1 common genes common pathways 24120:[DB00027 DB04575] DB00027|Gramicidin D ABCB1 DB04575|Quinestrol ESR1 common genes common pathways 24121:[DB00027 DB06350] DB00027|Gramicidin D ABCB1 DB06350|Elinogrel P2RY12 common genes common pathways 24122:[DB00027 DB00402] DB00027|Gramicidin D ABCB1 DB00402|Eszopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0042493| response to drug GABRG3;TSPO;ABCB1 GO:0006810| transport GABRB1;GABRG2;GABRA1;GABRA4;GABRA6;GABRB3;GABRA5;GABRA3;GABRB2;GABRD;ABCB1 24123:[DB00027 DB08039] DB00027|Gramicidin D ABCB1 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways GO:0055085| transmembrane transport CALM1;ABCB1 24124:[DB00027 DB13985] DB00027|Gramicidin D ABCB1 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways 24125:[DB00027 DB04615] DB00027|Gramicidin D ABCB1 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways 24126:[DB00027 DB01567] DB00027|Gramicidin D ABCB1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1 GO:0006810| transport GABRB2;GABRD;GABRA3;GABRA5;GABRR2;ABCB1;GABRA1;GABRR1;GABRG2;GABRB1;GABRB3 24127:[DB00027 DB04376] DB00027|Gramicidin D ABCB1 DB04376|13-Acetylphorbol PRKCD common genes common pathways 24128:[DB00027 DB00771] DB00027|Gramicidin D ABCB1 DB00771|Clidinium CHRM1 common genes common pathways 24129:[DB00027 DB00700] DB00027|Gramicidin D ABCB1 DB00700|Eplerenone NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP11B2 common genes common pathways 24130:[DB00027 DB07021] DB00027|Gramicidin D ABCB1 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways 24131:[DB00027 DB07202] DB00027|Gramicidin D ABCB1 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways 24132:[DB00027 DB08791] DB00027|Gramicidin D ABCB1 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways 24133:[DB00027 DB00107] DB00027|Gramicidin D ABCB1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0042493| response to drug OXTR;ABCB1 24134:[DB00027 DB00177] DB00027|Gramicidin D ABCB1 DB00177|Valsartan AGTR1;CYP2C9;ALB;SLCO1B3;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;SLCO1B1;ABCB1 24135:[DB00027 DB09214] DB00027|Gramicidin D ABCB1 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1 24136:[DB00027 DB00659] DB00027|Gramicidin D ABCB1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC36A1 GO:0006810| transport GRIN2A;GABRB3;GABRA1;GABRA4;GABRA6;GRIN2B;GABRG2;GABRB1;ABCB1;GABRD;GABRB2;GABRA5;GABRA3;GRIN2C GO:0042493| response to drug GABRG3;GRIN2A;ABCB1 24137:[DB00027 DB01609] DB00027|Gramicidin D ABCB1 DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;CYP1A2 24138:[DB00027 DB05540] DB00027|Gramicidin D ABCB1 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways 24139:[DB00027 DB09043] DB00027|Gramicidin D ABCB1 DB09043|Albiglutide GLP1R common genes common pathways 24140:[DB00027 DB00239] DB00027|Gramicidin D ABCB1 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 24141:[DB00027 DB00666] DB00027|Gramicidin D ABCB1 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways 24142:[DB00027 DB00412] DB00027|Gramicidin D ABCB1 DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;PPARG;CYP1A2 GO:0055085| transmembrane transport ABCB1;ABCB11;SLCO1B1 GO:0006810| transport ABCB11;ABCB1 24143:[DB00027 DB01608] DB00027|Gramicidin D ABCB1 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0006810| transport AR;ABCB1 GO:0042493| response to drug ABCB1;DRD1 24144:[DB00027 DB04224] DB00027|Gramicidin D ABCB1 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes common pathways GO:0042493| response to drug ABCB1;FABP3;PPARG 24145:[DB00027 DB06719] DB00027|Gramicidin D ABCB1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways 24146:[DB00027 DB14487] DB00027|Gramicidin D ABCB1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0042493| response to drug SOD1;MGMT;NME1;HDAC1;HDAC4;APOA2;TP53;MDM2;APOA1;ABCB1;TP73 GO:0055085| transmembrane transport ABCB1;APOA1 GO:0006810| transport TTR;ABCB1 24147:[DB00027 DB01119] DB00027|Gramicidin D ABCB1 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0042493| response to drug ABCB1;KCNJ11;ATP1A1 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0055085| transmembrane transport ABCB1;KCNMA1;KCNJ11;SLC12A3 GO:0006810| transport ABCB1;SLC12A3 24148:[DB00027 DB00026] DB00027|Gramicidin D ABCB1 DB00026|Anakinra IL1R1 common genes common pathways 24149:[DB00027 DB05490] DB00027|Gramicidin D ABCB1 DB05490|T131 PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 24150:[DB00027 DB00842] DB00027|Gramicidin D ABCB1 DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways GO:0006810| transport GABRR2;GABRA5;GABRA3;GABRD;GABRB2;ABCB1;GABRB1;GABRG2;GABRA6;GABRR1;GABRA4;GABRA1;GABRB3 GO:0042493| response to drug ABCB1;GABRG3 24151:[DB00027 DB04552] DB00027|Gramicidin D ABCB1 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0055085| transmembrane transport SLC16A1;SLC16A7;ABCB1;CLCNKA GO:0006810| transport CLCNKA;ABCB1 GO:0042493| response to drug ABCB1;PTGS2 24152:[DB00027 DB11217] DB00027|Gramicidin D ABCB1 DB11217|Arbutin TYR;ALB common genes common pathways 24153:[DB00027 DB03541] DB00027|Gramicidin D ABCB1 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0042493| response to drug ABCB1;TYMS 24154:[DB00027 DB05992] DB00027|Gramicidin D ABCB1 DB05992|Plinabulin TNF common genes common pathways 24155:[DB00027 DB01063] DB00027|Gramicidin D ABCB1 DB01063|Acetophenazine DRD2;DRD1;AR common genes common pathways GO:0042493| response to drug DRD1;ABCB1;DRD2 GO:0006810| transport AR;ABCB1 24156:[DB00027 DB00184] DB00027|Gramicidin D ABCB1 DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5 GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1;CYP1A1;MAOB GO:0055085| transmembrane transport ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A4;SLC22A5 GO:0006810| transport ABCB1;CHRNB3;CHRNA6 24157:[DB00027 DB06777] DB00027|Gramicidin D ABCB1 DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 24158:[DB00027 DB04310] DB00027|Gramicidin D ABCB1 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways 24159:[DB00027 DB08479] DB00027|Gramicidin D ABCB1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug ABCB1;TYMS 24160:[DB00027 DB00482] DB00027|Gramicidin D ABCB1 DB00482|Celecoxib PTGS2;PDPK1;CA2;CA3;ABCB5;ABCG2;ABCB1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;ABCC4;ABCB11 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCB5 GO:0006855| drug transmembrane transport ABCB5;ABCG2;ABCB1 GO:0006810| transport ABCB11;ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1;ABCB5;ABCC4;ABCB11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:1901529| ABCB1 GO:0042493| response to drug ABCB1;ABCG2;PTGS2;ABCC4 GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0099040| ABCB1 24161:[DB00027 DB01035] DB00027|Gramicidin D ABCB1 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0042493| response to drug ABCB1;BCHE GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1;SLC47A2;SCN5A;SLC47A1;SLC22A5;KCNH2;SLC22A3;SLC22A4 GO:0006855| drug transmembrane transport SLC47A1;SLC47A2;SLC22A3;SLC22A5;ABCB1;SLC22A2;SLC22A1 24162:[DB00027 DB11591] DB00027|Gramicidin D ABCB1 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport SLCO2B1;ABCB1;SLCO1A2;ABCB5 GO:0006855| drug transmembrane transport ABCB1;ABCB5 GO:0042908| xenobiotic transport ABCB1;ABCB5 24163:[DB00027 DB05352] DB00027|Gramicidin D ABCB1 DB05352|Fx-1006A TTR common genes common pathways GO:0006810| transport ABCB1;TTR 24164:[DB00027 DB05969] DB00027|Gramicidin D ABCB1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle CDK7;ABCB1 24165:[DB00027 DB00809] DB00027|Gramicidin D ABCB1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways 24166:[DB00027 DB02047] DB00027|Gramicidin D ABCB1 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways 24167:[DB00027 DB04879] DB00027|Gramicidin D ABCB1 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways 24168:[DB00027 DB02303] DB00027|Gramicidin D ABCB1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways 24169:[DB00027 DB00004] DB00027|Gramicidin D ABCB1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways 24170:[DB00027 DB05461] DB00027|Gramicidin D ABCB1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug HTR2B;ABCB1 24171:[DB00027 DB01238] DB00027|Gramicidin D ABCB1 DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;HTR2A;HTR2C;HTR1B;ABCB1;DRD2;ADRA1A;DRD3 24172:[DB00027 DB06710] DB00027|Gramicidin D ABCB1 DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0006810| transport AR;ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;SLC22A8 24173:[DB00027 DB04838] DB00027|Gramicidin D ABCB1 DB04838|Cyclandelate CACNA2D1;CES1;CYP3A4 common genes common pathways 24174:[DB00027 DB06202] DB00027|Gramicidin D ABCB1 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes common pathways 24175:[DB00027 DB08798] DB00027|Gramicidin D ABCB1 DB08798|Sulfamoxole CYP2C9 common genes common pathways 24176:[DB00027 DB05905] DB00027|Gramicidin D ABCB1 DB05905|TD-2749 HTR4 common genes common pathways 24177:[DB00027 DB07477] DB00027|Gramicidin D ABCB1 DB07477|Felbinac CTSL common genes common pathways 24178:[DB00027 DB01156] DB00027|Gramicidin D ABCB1 DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC22A2;SLC6A3;SLC6A2 GO:0042493| response to drug CYP2E1;SLC6A2;ABCB1;SLC6A3 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 24179:[DB00027 DB00496] DB00027|Gramicidin D ABCB1 DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways 24180:[DB00027 DB04070] DB00027|Gramicidin D ABCB1 DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways 24181:[DB00027 DB00807] DB00027|Gramicidin D ABCB1 DB00807|Proparacaine SCN10A common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCB1 24182:[DB00027 DB00318] DB00027|Gramicidin D ABCB1 DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0055085| transmembrane transport SLC22A1;ABCB1 24183:[DB00027 DB01972] DB00027|Gramicidin D ABCB1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0055085| transmembrane transport ABCB1;DLG4 24184:[DB00027 DB01217] DB00027|Gramicidin D ABCB1 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 24185:[DB00027 DB05662] DB00027|Gramicidin D ABCB1 DB05662|NP-50301 ESR1 common genes common pathways 24186:[DB00027 DB05511] DB00027|Gramicidin D ABCB1 DB05511|Piclidenoson ADORA3 common genes common pathways 24187:[DB00027 DB06879] DB00027|Gramicidin D ABCB1 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways 24188:[DB00027 DB07637] DB00027|Gramicidin D ABCB1 DB07637|Dibromotyrosine EPOR common genes common pathways 24189:[DB00027 DB06791] DB00027|Gramicidin D ABCB1 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways 24190:[DB00027 DB03158] DB00027|Gramicidin D ABCB1 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways 24191:[DB00027 DB05202] DB00027|Gramicidin D ABCB1 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways 24192:[DB00027 DB01622] DB00027|Gramicidin D ABCB1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0042493| response to drug DRD1;HTR2A;DRD2;ADRA1A;ABCB1 24193:[DB00027 DB09286] DB00027|Gramicidin D ABCB1 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0042493| response to drug HTR2A;DRD1;DRD3;HTR2B;ABCB1;DRD2;ADRA1A 24194:[DB00027 DB01062] DB00027|Gramicidin D ABCB1 DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways 24195:[DB00027 DB00780] DB00027|Gramicidin D ABCB1 DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways GO:0042493| response to drug CYP2E1;ABAT;ABCB1;MAOB 24196:[DB00027 DB05188] DB00027|Gramicidin D ABCB1 DB05188|KD3010 PPARD common genes common pathways 24197:[DB00027 DB05767] DB00027|Gramicidin D ABCB1 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways 24198:[DB00027 DB06820] DB00027|Gramicidin D ABCB1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 24199:[DB00027 DB01320] DB00027|Gramicidin D ABCB1 DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A GO:0042493| response to drug CYP1A2;ABCB1 24200:[DB00027 DB00871] DB00027|Gramicidin D ABCB1 DB00871|Terbutaline ADRB2;ADRB3;ADRB1;BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCB1 24201:[DB00027 DB00933] DB00027|Gramicidin D ABCB1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;HTR2A 24202:[DB00027 DB00500] DB00027|Gramicidin D ABCB1 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0042493| response to drug PTGS2;ABCB1 24203:[DB00027 DB13869] DB00027|Gramicidin D ABCB1 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways 24204:[DB00027 DB00804] DB00027|Gramicidin D ABCB1 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 24205:[DB00027 DB02820] DB00027|Gramicidin D ABCB1 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways 24206:[DB00027 DB00223] DB00027|Gramicidin D ABCB1 DB00223|Diflorasone NR3C1 common genes common pathways 24207:[DB00027 DB02481] DB00027|Gramicidin D ABCB1 DB02481|N-Benzylformamide ADH1B common genes common pathways 24208:[DB00027 DB00106] DB00027|Gramicidin D ABCB1 DB00106|Abarelix GNRHR common genes common pathways 24209:[DB00027 DB00014] DB00027|Gramicidin D ABCB1 DB00014|Goserelin LHCGR;GNRHR common genes common pathways 24210:[DB00027 DB09118] DB00027|Gramicidin D ABCB1 DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;LDHA;GABRG3;CYP1A2 GO:0006810| transport GABRG2;GABRB1;GABRA1;GABRA6;GABRA4;GABRB3;GABRA3;GABRA5;GABRD;GABRB2;ABCB1 24211:[DB00027 DB14514] DB00027|Gramicidin D ABCB1 DB14514|Magnesium levulinate ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1 24212:[DB00027 DB04278] DB00027|Gramicidin D ABCB1 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways 24213:[DB00027 DB04787] DB00027|Gramicidin D ABCB1 DB04787|Tanaproget PGR common genes common pathways 24214:[DB00027 DB01116] DB00027|Gramicidin D ABCB1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE 24215:[DB00027 DB11943] DB00027|Gramicidin D ABCB1 DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1;ABCB5 GO:0006855| drug transmembrane transport ABCG2;ABCB1;ABCB5 GO:0042493| response to drug CYP2E1;UGT1A1;ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1;ABCB5 24216:[DB00027 DB01558] DB00027|Gramicidin D ABCB1 DB01558|Bromazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;CYP2E1;GABRG3 GO:0006810| transport GABRA1;GABRA4;GABRA6;GABRR1;GABRG2;GABRB1;GABRB3;GABRB2;GABRD;GABRA3;GABRA5;GABRR2;ABCB1 24217:[DB00027 DB08932] DB00027|Gramicidin D ABCB1 DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes common pathways 24218:[DB00027 DB07675] DB00027|Gramicidin D ABCB1 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 24219:[DB00027 DB05038] DB00027|Gramicidin D ABCB1 DB05038|Anatibant BDKRB2 common genes common pathways 24220:[DB00027 DB13975] DB00027|Gramicidin D ABCB1 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 24221:[DB00027 DB06213] DB00027|Gramicidin D ABCB1 DB06213|Regadenoson ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;ABCB1 24222:[DB00027 DB09327] DB00027|Gramicidin D ABCB1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0042493| response to drug ABCB1;TYMS GO:0055085| transmembrane transport ABCB1;SLC22A7 24223:[DB00027 DB00042] DB00027|Gramicidin D ABCB1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 24224:[DB00027 DB08386] DB00027|Gramicidin D ABCB1 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 24225:[DB00027 DB00891] DB00027|Gramicidin D ABCB1 DB00891|Sulfapyridine CYP2C9 common genes common pathways 24226:[DB00027 DB04655] DB00027|Gramicidin D ABCB1 DB04655|Metoprine HNMT common genes common pathways 24227:[DB00027 DB08744] DB00027|Gramicidin D ABCB1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways 24228:[DB00027 DB04253] DB00027|Gramicidin D ABCB1 DB04253|Tretazicar NQO2 common genes common pathways 24229:[DB00027 DB06314] DB00027|Gramicidin D ABCB1 DB06314|SGX-523 MET common genes common pathways 24230:[DB00027 DB11811] DB00027|Gramicidin D ABCB1 DB11811|Arhalofenate PPARG common genes common pathways GO:0042493| response to drug PPARG;ABCB1 24231:[DB00027 DB05246] DB00027|Gramicidin D ABCB1 DB05246|Methsuximide CACNA1G;CYP2C19 common genes common pathways GO:0055085| transmembrane transport ABCB1;CACNA1G 24232:[DB00027 DB00938] DB00027|Gramicidin D ABCB1 DB00938|Salmeterol ADRB2;ADRB1;ADRB3;CYP3A4;CYP3A5;CYP3A7;CYP2C8 common genes common pathways 24233:[DB00027 DB05259] DB00027|Gramicidin D ABCB1 DB05259|Glatiramer HLA-DRB1 common genes common pathways 24234:[DB00027 DB00546] DB00027|Gramicidin D ABCB1 DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1 GO:0006810| transport ABCB1;GABRD;GABRB2;GABRA3;GABRA5;GABRR2;GABRB3;GABRA1;GABRR1;GABRG2;GABRB1 24235:[DB00027 DB11254] DB00027|Gramicidin D ABCB1 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0042493| response to drug ABCB1;TOP1 24236:[DB00027 DB14700] DB00027|Gramicidin D ABCB1 DB14700|Damoctocog alfa pegol F8 common genes common pathways 24237:[DB00027 DB01158] DB00027|Gramicidin D ABCB1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 24238:[DB00027 DB09381] DB00027|Gramicidin D ABCB1 DB09381|Estrogens, esterified CYP3A4 common genes common pathways 24239:[DB00027 DB00418] DB00027|Gramicidin D ABCB1 DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;GRIN2A GO:0006810| transport GABRA1;GABRA6;GRIK2;GABRA4;GRIN2B;GRIN2A;GABRA5;GABRA3;GRIN2C;ABCB1 GO:0055085| transmembrane transport GRIK2;ABCB1 24240:[DB00027 DB06752] DB00027|Gramicidin D ABCB1 DB06752|Chymopapain PRG2 common genes common pathways 24241:[DB00027 DB09095] DB00027|Gramicidin D ABCB1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways 24242:[DB00027 DB13345] DB00027|Gramicidin D ABCB1 DB13345|Dihydroergocristine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD1;DRD5;DRD2;DRD3;DRD4;CYP3A4;ABCB11 common genes common pathways GO:0006810| transport ABCB1;ABCB11 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0042493| response to drug DRD3;HTR2C;HTR2B;ABCB1;HTR1B;DRD2;ADRA1A;HTR2A;DRD1 24243:[DB00027 DB06558] DB00027|Gramicidin D ABCB1 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways 24244:[DB00027 DB13915] DB00027|Gramicidin D ABCB1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways 24245:[DB00027 DB06623] DB00027|Gramicidin D ABCB1 DB06623|Flupirtine ADRA2A common genes common pathways 24246:[DB00027 DB05793] DB00027|Gramicidin D ABCB1 DB05793|PRO-542 FFAR4 common genes common pathways 24247:[DB00027 DB09244] DB00027|Gramicidin D ABCB1 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways 24248:[DB00027 DB00387] DB00027|Gramicidin D ABCB1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways 24249:[DB00027 DB11718] DB00027|Gramicidin D ABCB1 DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0042493| response to drug ABCB1;CCND1 24250:[DB00027 DB05133] DB00027|Gramicidin D ABCB1 DB05133|VP025 IL1B common genes common pathways 24251:[DB00027 DB00956] DB00027|Gramicidin D ABCB1 DB00956|Hydrocodone OPRM1;OPRD1;CYP2D6;CYP3A4 common genes common pathways 24252:[DB00027 DB01235] DB00027|Gramicidin D ABCB1 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;DRD3;DRD1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC16A10 GO:0006810| transport SLC15A1;SLC7A5;ABCB1;SLC7A8 24253:[DB00027 DB03742] DB00027|Gramicidin D ABCB1 DB03742|Compound 4-D ESR1 common genes common pathways 24254:[DB00027 DB02709] DB00027|Gramicidin D ABCB1 DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2;SLC2A1 GO:0006810| transport ABCB1;TTR GO:0055085| transmembrane transport ABCB1;SLC2A1 GO:0042493| response to drug ABCB1;SNCA;CYP1A1;PPARG;CYP1A2;PTGS2 24255:[DB00027 DB01278] DB00027|Gramicidin D ABCB1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways 24256:[DB00027 DB01269] DB00027|Gramicidin D ABCB1 DB01269|Panitumumab EGFR common genes common pathways 24257:[DB00027 DB09126] DB00027|Gramicidin D ABCB1 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways 24258:[DB00027 DB05369] DB00027|Gramicidin D ABCB1 DB05369|HZT-501 HRH2 common genes common pathways 24259:[DB00027 DB01348] DB00027|Gramicidin D ABCB1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 24260:[DB00027 DB00961] DB00027|Gramicidin D ABCB1 DB00961|Mepivacaine SCN10A common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCB1 24261:[DB00027 DB04703] DB00027|Gramicidin D ABCB1 DB04703|Hesperidin AURKB common genes common pathways 24262:[DB00027 DB06825] DB00027|Gramicidin D ABCB1 DB06825|Triptorelin GNRHR common genes common pathways 24263:[DB00027 DB01941] DB00027|Gramicidin D ABCB1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways 24264:[DB00027 DB01565] DB00027|Gramicidin D ABCB1 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways 24265:[DB00027 DB14575] DB00027|Gramicidin D ABCB1 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 24266:[DB00027 DB13149] DB00027|Gramicidin D ABCB1 DB13149|Protein S human F5;F10;PROC common genes common pathways 24267:[DB00027 DB12406] DB00027|Gramicidin D ABCB1 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 24268:[DB00027 DB09199] DB00027|Gramicidin D ABCB1 DB09199|Netoglitazone CYP3A4;CYP2C8 common genes common pathways 24269:[DB00027 DB07393] DB00027|Gramicidin D ABCB1 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways 24270:[DB00027 DB01839] DB00027|Gramicidin D ABCB1 DB01839|Propylene glycol F13A1 common genes common pathways 24271:[DB00027 DB05675] DB00027|Gramicidin D ABCB1 DB05675|EP-2104R FGA common genes common pathways 24272:[DB00027 DB08996] DB00027|Gramicidin D ABCB1 DB08996|Dimetacrine ACHE common genes common pathways 24273:[DB00027 DB02262] DB00027|Gramicidin D ABCB1 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0042493| response to drug ABCB1;DHODH 24274:[DB00027 DB01135] DB00027|Gramicidin D ABCB1 DB01135|Doxacurium CHRNA2;CHRM2;BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCB1 24275:[DB00027 DB03222] DB00027|Gramicidin D ABCB1 DB03222|dATP POLB;recA;recA common genes common pathways 24276:[DB00027 DB00327] DB00027|Gramicidin D ABCB1 DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways 24277:[DB00027 DB04776] DB00027|Gramicidin D ABCB1 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways 24278:[DB00027 DB07379] DB00027|Gramicidin D ABCB1 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways 24279:[DB00027 DB08439] DB00027|Gramicidin D ABCB1 DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 24280:[DB00027 DB07645] DB00027|Gramicidin D ABCB1 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways 24281:[DB00027 DB04660] DB00027|Gramicidin D ABCB1 DB04660|Choline alfoscerate GM2A common genes common pathways 24282:[DB00027 DB00073] DB00027|Gramicidin D ABCB1 DB00073|Rituximab MS4A1 common genes common pathways 24283:[DB00027 DB06494] DB00027|Gramicidin D ABCB1 DB06494|Sufugolix GNRHR common genes common pathways 24284:[DB00027 DB07108] DB00027|Gramicidin D ABCB1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways 24285:[DB00027 DB08642] DB00027|Gramicidin D ABCB1 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways 24286:[DB00027 DB09409] DB00027|Gramicidin D ABCB1 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways GO:0042493| response to drug ABCB1;GRIN2A GO:0006810| transport GRIN2C;ABCB1;GRIN2B;GRIN2A 24287:[DB00027 DB00048] DB00027|Gramicidin D ABCB1 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways GO:0042493| response to drug ABCB1;COL1A1 24288:[DB00027 DB02703] DB00027|Gramicidin D ABCB1 DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;ABCB11;ABCB1;ABCG2;ABCC2 GO:0006810| transport ABCG2;ABCC2;ABCB1;ABCB11 GO:0042493| response to drug ABCB1;ABCG2;ABCC2;UGT1A1 GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 24289:[DB00027 DB04581] DB00027|Gramicidin D ABCB1 DB04581|1-benzylimidazole QPCT common genes common pathways 24290:[DB00027 DB06264] DB00027|Gramicidin D ABCB1 DB06264|Tolperisone CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 24291:[DB00027 DB13835] DB00027|Gramicidin D ABCB1 DB13835|Caroverine CYP3A4 common genes common pathways 24292:[DB00027 DB01227] DB00027|Gramicidin D ABCB1 DB01227|Levacetylmethadol OPRM1;CHRNB4;CHRNA3;CYP3A5;CYP3A7;CYP3A4;CYP19A1 common genes common pathways 24293:[DB00027 DB01699] DB00027|Gramicidin D ABCB1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0042493| response to drug ABCB1;ABAT 24294:[DB00027 DB00268] DB00027|Gramicidin D ABCB1 DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2A;CYP1A2;DRD1;DRD3;HTR2C;HTR2B;DRD2;ABCB1;HTR1B 24295:[DB00027 DB06937] DB00027|Gramicidin D ABCB1 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways 24296:[DB00027 DB08169] DB00027|Gramicidin D ABCB1 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0042493| response to drug DHODH;ABCB1 24297:[DB00027 DB06263] DB00027|Gramicidin D ABCB1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0042908| xenobiotic transport ABCB5;ABCB1 GO:0006855| drug transmembrane transport ABCB5;ABCB1 GO:0042493| response to drug ABCB1;POR GO:0055085| transmembrane transport ABCB5;ABCB1 24298:[DB00027 DB00186] DB00027|Gramicidin D ABCB1 DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0006810| transport GABRB3;GABRG2;GABRB1;GABRA1;GABRA6;GABRA4;ABCB1;GABRA5;GABRA3;GABRD;GABRB2 GO:0042493| response to drug GABRG3;TSPO;ABCB1 24299:[DB00027 DB03725] DB00027|Gramicidin D ABCB1 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways 24300:[DB00027 DB05710] DB00027|Gramicidin D ABCB1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways 24301:[DB00027 DB00426] DB00027|Gramicidin D ABCB1 DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways 24302:[DB00027 DB06809] DB00027|Gramicidin D ABCB1 DB06809|Plerixafor CXCR4 common genes common pathways 24303:[DB00027 DB14545] DB00027|Gramicidin D ABCB1 DB14545|Hydrocortisone succinate CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP11B1;CYP11B2 common genes common pathways 24304:[DB00027 DB09068] DB00027|Gramicidin D ABCB1 DB09068|Vortioxetine SLC6A4;HTR3A;HTR7;HTR1B;HTR1A;ADRB1;CYP2D6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2A6;CYP2C8;CYP2B6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0042493| response to drug SLC6A4;ABCB1;HTR1B 24305:[DB00027 DB02165] DB00027|Gramicidin D ABCB1 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways 24306:[DB00027 DB01082] DB00027|Gramicidin D ABCB1 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 24307:[DB00027 DB02824] DB00027|Gramicidin D ABCB1 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways 24308:[DB00027 DB06757] DB00027|Gramicidin D ABCB1 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0042493| response to drug ARG1;ABCB1 24309:[DB00027 DB14526] DB00027|Gramicidin D ABCB1 DB14526|Chromic citrate CYB5A;TF common genes common pathways 24310:[DB00027 DB00753] DB00027|Gramicidin D ABCB1 DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0042493| response to drug CYP2E1;GABRG3;MT-ND1;ABCB1 GO:0006810| transport ABCB1;GABRB2;GABRD;GABRA5;GABRA3;GABRB3;GABRA1;GABRA6;GABRA4;GABRG2;GABRB1 GO:0055085| transmembrane transport CALM1;KCNA1;ABCB1 24311:[DB00027 DB01140] DB00027|Gramicidin D ABCB1 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC15A2;SLC22A5;SLC22A6;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 24312:[DB00027 DB12161] DB00027|Gramicidin D ABCB1 DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 GO:0055085| transmembrane transport ABCB1;SLC18A2 24313:[DB00027 DB00121] DB00027|Gramicidin D ABCB1 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways GO:0042493| response to drug ABCB1;ACACB GO:0055085| transmembrane transport SLC5A6;ABCB1 GO:0006810| transport ABCB1;SLC5A6 24314:[DB00027 DB05432] DB00027|Gramicidin D ABCB1 DB05432|DAS-431 IV CALY common genes common pathways 24315:[DB00027 DB08909] DB00027|Gramicidin D ABCB1 DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways 24316:[DB00027 DB01201] DB00027|Gramicidin D ABCB1 DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways 24317:[DB00027 DB05389] DB00027|Gramicidin D ABCB1 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways 24318:[DB00027 DB04901] DB00027|Gramicidin D ABCB1 DB04901|Galiximab CD80 common genes common pathways 24319:[DB00027 DB04574] DB00027|Gramicidin D ABCB1 DB04574|Estrone sulfate ESR1;ESR2;CYP3A4;CYP1A2;CYP2C9;SHBG;ALB;SLC47A1;SLC47A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC47A1;SLC47A2 GO:0042493| response to drug ABCB1;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;SLC47A1;SLC47A2 24320:[DB00027 DB06393] DB00027|Gramicidin D ABCB1 DB06393|Xaliproden HTR1A common genes common pathways 24321:[DB00027 DB01117] DB00027|Gramicidin D ABCB1 DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;MT-CYB;DHODH 24322:[DB00027 DB12582] DB00027|Gramicidin D ABCB1 DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 24323:[DB00027 DB04213] DB00027|Gramicidin D ABCB1 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways 24324:[DB00027 DB07232] DB00027|Gramicidin D ABCB1 DB07232|Veliparib PARP1;PARP2 common genes common pathways 24325:[DB00027 DB13909] DB00027|Gramicidin D ABCB1 DB13909|Bismuth subgallate ALB common genes common pathways 24326:[DB00027 DB03893] DB00027|Gramicidin D ABCB1 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways 24327:[DB00027 DB08262] DB00027|Gramicidin D ABCB1 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways 24328:[DB00027 DB05122] DB00027|Gramicidin D ABCB1 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways 24329:[DB00027 DB04065] DB00027|Gramicidin D ABCB1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways 24330:[DB00027 DB00844] DB00027|Gramicidin D ABCB1 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways 24331:[DB00027 DB08689] DB00027|Gramicidin D ABCB1 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways 24332:[DB00027 DB01112] DB00027|Gramicidin D ABCB1 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 24333:[DB00027 DB00934] DB00027|Gramicidin D ABCB1 DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A2;HTR2C;DRD2;ADRA1A;ABCB1;HTR2A;CYP1A2 24334:[DB00027 DB05079] DB00027|Gramicidin D ABCB1 DB05079|HY10275 HRH1;HTR2A common genes common pathways GO:0042493| response to drug ABCB1;HTR2A 24335:[DB00027 DB05403] DB00027|Gramicidin D ABCB1 DB05403|CEP-1347 MAPK12 common genes common pathways 24336:[DB00027 DB05961] DB00027|Gramicidin D ABCB1 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways 24337:[DB00027 DB04982] DB00027|Gramicidin D ABCB1 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways GO:0006810| transport GRIA4;ABCB1;GRIA3 24338:[DB00027 DB11386] DB00027|Gramicidin D ABCB1 DB11386|Chlorobutanol KCNH2 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCB1 24339:[DB00027 DB06021] DB00027|Gramicidin D ABCB1 DB06021|AV-412 EGFR;ERBB2 common genes common pathways 24340:[DB00027 DB04869] DB00027|Gramicidin D ABCB1 DB04869|Olcegepant CALCA;CALCRL common genes common pathways 24341:[DB00027 DB14003] DB00027|Gramicidin D ABCB1 DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1;TTPA GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 24342:[DB00027 DB09128] DB00027|Gramicidin D ABCB1 DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;DRD2;HTR2A 24343:[DB00027 DB09202] DB00027|Gramicidin D ABCB1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A 24344:[DB00027 DB00141] DB00027|Gramicidin D ABCB1 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways 24345:[DB00027 DB03904] DB00027|Gramicidin D ABCB1 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways GO:0042493| response to drug ABCB1;CTNNB1;ARG1 GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0055085| transmembrane transport SLC14A2;SLC14A1;ABCB1 24346:[DB00027 DB07177] DB00027|Gramicidin D ABCB1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 24347:[DB00027 DB03793] DB00027|Gramicidin D ABCB1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC16A1;SLC15A1;ABCB1;SLCO2B1 GO:0006810| transport ABCB1;SLC15A1 24348:[DB00027 DB02925] DB00027|Gramicidin D ABCB1 DB02925|Piretanide SLC12A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC12A1 GO:0006810| transport ABCB1;SLC12A1 24349:[DB00027 DB06273] DB00027|Gramicidin D ABCB1 DB06273|Tocilizumab IL6R;CYP3A4 common genes common pathways 24350:[DB00027 DB08232] DB00027|Gramicidin D ABCB1 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways 24351:[DB00027 DB13501] DB00027|Gramicidin D ABCB1 DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 24352:[DB00027 DB00603] DB00027|Gramicidin D ABCB1 DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways 24353:[DB00027 DB02731] DB00027|Gramicidin D ABCB1 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways GO:0042493| response to drug OXCT1;ABCB1 24354:[DB00027 DB07984] DB00027|Gramicidin D ABCB1 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways 24355:[DB00027 DB07983] DB00027|Gramicidin D ABCB1 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways 24356:[DB00027 DB13293] DB00027|Gramicidin D ABCB1 DB13293|Ipecac CYP2D6;CYP3A4 common genes common pathways 24357:[DB00027 DB01616] DB00027|Gramicidin D ABCB1 DB01616|Alverine HTR1A common genes common pathways 24358:[DB00027 DB07769] DB00027|Gramicidin D ABCB1 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0006810| transport AR;ABCB1 24359:[DB00027 DB01250] DB00027|Gramicidin D ABCB1 DB01250|Olsalazine TPMT;IFNG common genes common pathways 24360:[DB00027 DB00881] DB00027|Gramicidin D ABCB1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC15A2;SLC15A1;ABCB1 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 24361:[DB00027 DB07454] DB00027|Gramicidin D ABCB1 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0006810| transport AR;ABCB1 24362:[DB00027 DB09117] DB00027|Gramicidin D ABCB1 DB09117|Paraldehyde ALDH2 common genes common pathways 24363:[DB00027 DB00170] DB00027|Gramicidin D ABCB1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0042493| response to drug CYP1A2;MTHFR;CYP2E1;CYP1A1;ABCB1 24364:[DB00027 DB08577] DB00027|Gramicidin D ABCB1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways 24365:[DB00027 DB01333] DB00027|Gramicidin D ABCB1 DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;SLC47A1;ABCB1 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport SLC47A1;SLC22A5;SLC15A2;ABCB1;SLC15A1;SLC22A6 24366:[DB00027 DB00065] DB00027|Gramicidin D ABCB1 DB00065|Infliximab TNF common genes common pathways 24367:[DB00027 DB05214] DB00027|Gramicidin D ABCB1 DB05214|KD7040 NOS2 common genes common pathways 24368:[DB00027 DB13857] DB00027|Gramicidin D ABCB1 DB13857|Demegestone PGR;CYP3A4 common genes common pathways 24369:[DB00027 DB00587] DB00027|Gramicidin D ABCB1 DB00587|Cinalukast CYSLTR1 common genes common pathways 24370:[DB00027 DB05939] DB00027|Gramicidin D ABCB1 DB05939|MK-0354 GPER1 common genes common pathways 24371:[DB00027 DB06168] DB00027|Gramicidin D ABCB1 DB06168|Canakinumab IL1B common genes common pathways 24372:[DB00027 DB00272] DB00027|Gramicidin D ABCB1 DB00272|Betazole HRH2 common genes common pathways 24373:[DB00027 DB00952] DB00027|Gramicidin D ABCB1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0042493| response to drug ABCB1;HTR1B 24374:[DB00027 DB12662] DB00027|Gramicidin D ABCB1 DB12662|Naveglitazar PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 24375:[DB00027 DB11328] DB00027|Gramicidin D ABCB1 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways 24376:[DB00027 DB09147] DB00027|Gramicidin D ABCB1 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways 24377:[DB00027 DB00109] DB00027|Gramicidin D ABCB1 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 24378:[DB00027 DB02371] DB00027|Gramicidin D ABCB1 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways 24379:[DB00027 DB02028] DB00027|Gramicidin D ABCB1 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways 24380:[DB00027 DB07209] DB00027|Gramicidin D ABCB1 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 24381:[DB00027 DB08583] DB00027|Gramicidin D ABCB1 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways 24382:[DB00027 DB00646] DB00027|Gramicidin D ABCB1 DB00646|Nystatin CYP3A4;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 24383:[DB00027 DB00222] DB00027|Gramicidin D ABCB1 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNJ11;ABCC8;ABCB11 GO:0006810| transport ABCB11;ABCB1 GO:0042493| response to drug ABCB1;ABCC8;KCNJ11 24384:[DB00027 DB00721] DB00027|Gramicidin D ABCB1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0042493| response to drug MAOB;BCHE;SLC6A3;ABCB1 GO:0055085| transmembrane transport KCNMA1;SLC6A3;ABCB1;SCN10A GO:0045332| phospholipid translocation KCNN4;ABCB1 24385:[DB00027 DB14507] DB00027|Gramicidin D ABCB1 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006810| transport ABCB1;GRIA3 24386:[DB00027 DB01195] DB00027|Gramicidin D ABCB1 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0055085| transmembrane transport KCNH2;SCN5A;SCN4A;ABCB1 24387:[DB00027 DB11071] DB00027|Gramicidin D ABCB1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 24388:[DB00027 DB08191] DB00027|Gramicidin D ABCB1 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways 24389:[DB00027 DB13257] DB00027|Gramicidin D ABCB1 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes common pathways GO:0042493| response to drug CAT;PTGS2;ABCB1 24390:[DB00027 DB05232] DB00027|Gramicidin D ABCB1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways GO:0055085| transmembrane transport SCN3A;SCN2A;ABCB1;SCN1A;SCN8A 24391:[DB00027 DB00056] DB00027|Gramicidin D ABCB1 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 24392:[DB00027 DB08478] DB00027|Gramicidin D ABCB1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug ABCB1;TYMS 24393:[DB00027 DB07931] DB00027|Gramicidin D ABCB1 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 24394:[DB00027 DB07112] DB00027|Gramicidin D ABCB1 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways 24395:[DB00027 DB01827] DB00027|Gramicidin D ABCB1 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways 24396:[DB00027 DB00996] DB00027|Gramicidin D ABCB1 DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0006810| transport GRIN2B;CACNA1B;GRIN2A;GRIN2C;ABCB1 GO:0055085| transmembrane transport ABCB1;CACNA1B GO:0042493| response to drug GRIN2A;ABCB1 24397:[DB00027 DB11219] DB00027|Gramicidin D ABCB1 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways GO:0006810| transport AR;ABCB1 24398:[DB00027 DB03732] DB00027|Gramicidin D ABCB1 DB03732|Etheno-Nadp BST1 common genes common pathways 24399:[DB00027 DB08970] DB00027|Gramicidin D ABCB1 DB08970|Fluprednidene CYP3A4 common genes common pathways 24400:[DB00027 DB03382] DB00027|Gramicidin D ABCB1 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways GO:0042493| response to drug ABCB1;SOD1 24401:[DB00027 DB06637] DB00027|Gramicidin D ABCB1 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0055085| transmembrane transport KCNC3;KCNA3;KCNB1;KCNA5;SLC22A2;ABCB1;KCNA7;KCNA1;KCNA4;KCNC2;KCNC1;KCND2;KCNA6;KCNA2;KCNB2;KCND3;KCND1;KCNA10 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 24402:[DB00027 DB08790] DB00027|Gramicidin D ABCB1 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways 24403:[DB00027 DB03935] DB00027|Gramicidin D ABCB1 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways GO:0072089| stem cell proliferation FGF2;ABCB1 24404:[DB00027 DB00722] DB00027|Gramicidin D ABCB1 DB00722|Lisinopril ACE common genes common pathways 24405:[DB00027 DB01746] DB00027|Gramicidin D ABCB1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways GO:0006810| transport SLC7A5;ABCB1 GO:0055085| transmembrane transport SLC16A10;ABCB1 24406:[DB00027 DB09031] DB00027|Gramicidin D ABCB1 DB09031|Miltefosine ABCB1;PLD1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006855| drug transmembrane transport ABCB1 24407:[DB00027 DB08429] DB00027|Gramicidin D ABCB1 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways 24408:[DB00027 DB02217] DB00027|Gramicidin D ABCB1 DB02217|Dpb-T NT5M common genes common pathways 24409:[DB00027 DB01406] DB00027|Gramicidin D ABCB1 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0006810| transport ABCB1;AR 24410:[DB00027 DB09552] DB00027|Gramicidin D ABCB1 DB09552|Thonzonium ATP6V1C1 common genes common pathways 24411:[DB00027 DB03480] DB00027|Gramicidin D ABCB1 DB03480|Brequinar Analog DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH 24412:[DB00027 DB04531] DB00027|Gramicidin D ABCB1 DB04531|Benzylcysteine MGMT common genes common pathways GO:0042493| response to drug ABCB1;MGMT 24413:[DB00027 DB01215] DB00027|Gramicidin D ABCB1 DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006810| transport GABRG2;GABRB1;GABRA1;GABRA6;GABRR1;GABRA4;GABRB3;GABRA3;GABRA5;GABRR2;GABRB2;GABRD;ABCB1 GO:0042493| response to drug GABRG3;ABCB1 24414:[DB00027 DB01181] DB00027|Gramicidin D ABCB1 DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 24415:[DB00027 DB06708] DB00027|Gramicidin D ABCB1 DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways 24416:[DB00027 DB05035] DB00027|Gramicidin D ABCB1 DB05035|Eprotirome THRA;THRB common genes common pathways 24417:[DB00027 DB00672] DB00027|Gramicidin D ABCB1 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0042493| response to drug ABCB1;ABCC8 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport SLC15A2;ABCC8;SLC22A6;SLC15A1;ABCB1 24418:[DB00027 DB06729] DB00027|Gramicidin D ABCB1 DB06729|Sulfaphenazole CYP2C9;CYP2B6;CYP2C8;CYP2D6 common genes common pathways 24419:[DB00027 DB11079] DB00027|Gramicidin D ABCB1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2 24420:[DB00027 DB02300] DB00027|Gramicidin D ABCB1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways 24421:[DB00027 DB08437] DB00027|Gramicidin D ABCB1 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways 24422:[DB00027 DB08313] DB00027|Gramicidin D ABCB1 DB08313|nocodazole HPGDS common genes common pathways 24423:[DB00027 DB04752] DB00027|Gramicidin D ABCB1 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways 24424:[DB00027 DB12747] DB00027|Gramicidin D ABCB1 DB12747|Tertomotide TERT common genes common pathways 24425:[DB00027 DB13170] DB00027|Gramicidin D ABCB1 DB13170|Plecanatide GUCY1A2 common genes common pathways 24426:[DB00027 DB01073] DB00027|Gramicidin D ABCB1 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways 24427:[DB00027 DB00436] DB00027|Gramicidin D ABCB1 DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways GO:0055085| transmembrane transport KCNMA1;SLC12A3;ABCB1 GO:0006810| transport SLC12A3;ABCB1 GO:2001225| regulation of chloride transport ABCB1;CA2 24428:[DB00027 DB03983] DB00027|Gramicidin D ABCB1 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways 24429:[DB00027 DB00092] DB00027|Gramicidin D ABCB1 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways 24430:[DB00027 DB00953] DB00027|Gramicidin D ABCB1 DB00953|Rizatriptan HTR1D;HTR1B;HTR1F;MAOA common genes common pathways GO:0042493| response to drug HTR1B;ABCB1 24431:[DB00027 DB13983] DB00027|Gramicidin D ABCB1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0006810| transport GABRA1;GABRA6;GABRA4;GABRG2;ABCB1;GABRA3;GABRA5 GO:0042493| response to drug ABCB1;GABRG3 24432:[DB00027 DB08383] DB00027|Gramicidin D ABCB1 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways 24433:[DB00027 DB00990] DB00027|Gramicidin D ABCB1 DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways 24434:[DB00027 DB02895] DB00027|Gramicidin D ABCB1 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways 24435:[DB00027 DB11750] DB00027|Gramicidin D ABCB1 DB11750|Clobetasol CYP3A4 common genes common pathways 24436:[DB00027 DB06766] DB00027|Gramicidin D ABCB1 DB06766|Alcaftadine HRH1 common genes common pathways 24437:[DB00027 DB02967] DB00027|Gramicidin D ABCB1 DB02967|N-Ethylmaleimide CLC common genes common pathways 24438:[DB00027 DB00484] DB00027|Gramicidin D ABCB1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways 24439:[DB00027 DB01954] DB00027|Gramicidin D ABCB1 DB01954|Rolipram PDE4D;PDE4B common genes common pathways 24440:[DB00027 DB05207] DB00027|Gramicidin D ABCB1 DB05207|SD118 TNF;IL1R1 common genes common pathways 24441:[DB00027 DB06677] DB00027|Gramicidin D ABCB1 DB06677|Clazosentan EDNRA common genes common pathways 24442:[DB00027 DB04258] DB00027|Gramicidin D ABCB1 DB04258|Seocalcitol VDR common genes common pathways 24443:[DB00027 DB01188] DB00027|Gramicidin D ABCB1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;ABCB1 24444:[DB00027 DB11737] DB00027|Gramicidin D ABCB1 DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 24445:[DB00027 DB06548] DB00027|Gramicidin D ABCB1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways 24446:[DB00027 DB11098] DB00027|Gramicidin D ABCB1 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways GO:0006810| transport SLC12A1;SLC12A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC12A1;SLC12A2 24447:[DB00027 DB04372] DB00027|Gramicidin D ABCB1 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 24448:[DB00027 DB00905] DB00027|Gramicidin D ABCB1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways 24449:[DB00027 DB00466] DB00027|Gramicidin D ABCB1 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1 GO:0006810| transport GABRA1;GABRR1;ABCB1 24450:[DB00027 DB01078] DB00027|Gramicidin D ABCB1 DB01078|Deslanoside ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1 24451:[DB00027 DB09139] DB00027|Gramicidin D ABCB1 DB09139|Technetium Tc-99m oxidronate ALB common genes common pathways 24452:[DB00027 DB11945] DB00027|Gramicidin D ABCB1 DB11945|Avelumab CD274 common genes common pathways 24453:[DB00027 DB01786] DB00027|Gramicidin D ABCB1 DB01786|D-Alanine SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 24454:[DB00027 DB04451] DB00027|Gramicidin D ABCB1 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways 24455:[DB00027 DB01225] DB00027|Gramicidin D ABCB1 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways 24456:[DB00027 DB01020] DB00027|Gramicidin D ABCB1 DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways 24457:[DB00027 DB06258] DB00027|Gramicidin D ABCB1 DB06258|Bimoclomol HSF1 common genes common pathways 24458:[DB00027 DB01260] DB00027|Gramicidin D ABCB1 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways 24459:[DB00027 DB05624] DB00027|Gramicidin D ABCB1 DB05624|Teverelix GNRHR common genes common pathways 24460:[DB00027 DB04020] DB00027|Gramicidin D ABCB1 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways 24461:[DB00027 DB05119] DB00027|Gramicidin D ABCB1 DB05119|Rilapladib PLA2G7 common genes common pathways 24462:[DB00027 DB07723] DB00027|Gramicidin D ABCB1 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG 24463:[DB00027 DB08038] DB00027|Gramicidin D ABCB1 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 24464:[DB00027 DB04711] DB00027|Gramicidin D ABCB1 DB04711|Iodipamide ALB common genes common pathways 24465:[DB00027 DB03510] DB00027|Gramicidin D ABCB1 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways 24466:[DB00027 DB01065] DB00027|Gramicidin D ABCB1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0042493| response to drug CYP1A2;CYP1A1;CALR;ABCB1 GO:0055085| transmembrane transport CALM1;SLC22A8;ABCB1 24467:[DB00027 DB04830] DB00027|Gramicidin D ABCB1 DB04830|Buformin SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0055085| transmembrane transport ABCB1;SLC22A1 24468:[DB00027 DB06681] DB00027|Gramicidin D ABCB1 DB06681|Belatacept CD86;CD80 common genes common pathways 24469:[DB00027 DB04664] DB00027|Gramicidin D ABCB1 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways 24470:[DB00027 DB01535] DB00027|Gramicidin D ABCB1 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways 24471:[DB00027 DB00679] DB00027|Gramicidin D ABCB1 DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0042493| response to drug ADRA1A;DRD2;ABCB1;CYP2E1;HTR2A;DRD1 24472:[DB00027 DB00280] DB00027|Gramicidin D ABCB1 DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A2;SLC22A1 GO:0042493| response to drug ABCB1;CYP1A2 GO:0055085| transmembrane transport ABCB1;SLC22A2;SLC22A1;SCN5A;KCND3;KCNH2;KCND2 24473:[DB00027 DB06897] DB00027|Gramicidin D ABCB1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle PLK1;ABCB1 24474:[DB00027 DB05150] DB00027|Gramicidin D ABCB1 DB05150|CAD106 APP common genes common pathways 24475:[DB00027 DB01381] DB00027|Gramicidin D ABCB1 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport GABRG2;GABRA1;SLC6A2;GABRB2;ABCB1 GO:0042493| response to drug ABCB1;SLC6A2 24476:[DB00027 DB01283] DB00027|Gramicidin D ABCB1 DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;PTGS2;ABCB1 24477:[DB00027 DB04150] DB00027|Gramicidin D ABCB1 DB04150|Threonine Derivative PAM common genes common pathways GO:0042493| response to drug ABCB1;PAM 24478:[DB00027 DB01166] DB00027|Gramicidin D ABCB1 DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;PDE3A 24479:[DB00027 DB04716] DB00027|Gramicidin D ABCB1 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways 24480:[DB00027 DB06835] DB00027|Gramicidin D ABCB1 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 24481:[DB00027 DB01003] DB00027|Gramicidin D ABCB1 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNMA1 24482:[DB00027 DB05311] DB00027|Gramicidin D ABCB1 DB05311|Ecallantide KLKB1 common genes common pathways 24483:[DB00027 DB11597] DB00027|Gramicidin D ABCB1 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 24484:[DB00027 DB07033] DB00027|Gramicidin D ABCB1 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways 24485:[DB00027 DB01241] DB00027|Gramicidin D ABCB1 DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;UGT1A1 GO:0055085| transmembrane transport ABCB1;SLCO1B1 24486:[DB00027 DB00778] DB00027|Gramicidin D ABCB1 DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0042493| response to drug ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 24487:[DB00027 DB00022] DB00027|Gramicidin D ABCB1 DB00022|Peginterferon alfa-2b IFNAR1;IFNAR2;CYP1A2;CYP2D6;CYP2C9 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2 24488:[DB00027 DB03408] DB00027|Gramicidin D ABCB1 DB03408|gamma-Glutamylcysteine GSS common genes common pathways 24489:[DB00027 DB01830] DB00027|Gramicidin D ABCB1 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways GO:0042493| response to drug ABCB1;LCK 24490:[DB00027 DB11475] DB00027|Gramicidin D ABCB1 DB11475|Tylosin CYP3A4 common genes common pathways 24491:[DB00027 DB08933] DB00027|Gramicidin D ABCB1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes common pathways 24492:[DB00027 DB05465] DB00027|Gramicidin D ABCB1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways 24493:[DB00027 DB11632] DB00027|Gramicidin D ABCB1 DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes common pathways GO:0042493| response to drug ABCB1;COMT 24494:[DB00027 DB00181] DB00027|Gramicidin D ABCB1 DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 24495:[DB00027 DB02676] DB00027|Gramicidin D ABCB1 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways 24496:[DB00027 DB02555] DB00027|Gramicidin D ABCB1 DB02555|SP4160 IL2 common genes common pathways 24497:[DB00027 DB08891] DB00027|Gramicidin D ABCB1 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways 24498:[DB00027 DB01884] DB00027|Gramicidin D ABCB1 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways 24499:[DB00027 DB01060] DB00027|Gramicidin D ABCB1 DB01060|Amoxicillin CYP2C19;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;SLC15A1;ABCB1;SLC15A2 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 24500:[DB00027 DB06160] DB00027|Gramicidin D ABCB1 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1 24501:[DB00027 DB04839] DB00027|Gramicidin D ABCB1 DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0006810| transport AR;ABCB1 24502:[DB00027 DB03881] DB00027|Gramicidin D ABCB1 DB03881|MT-Immucillin-H PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1 24503:[DB00027 DB01276] DB00027|Gramicidin D ABCB1 DB01276|Exenatide GLP1R;ALB common genes common pathways 24504:[DB00027 DB14040] DB00027|Gramicidin D ABCB1 DB14040|Eptinezumab CALCA;CALCB common genes common pathways 24505:[DB00027 DB01949] DB00027|Gramicidin D ABCB1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 24506:[DB00027 DB05217] DB00027|Gramicidin D ABCB1 DB05217|GMX1777 NAMPT common genes common pathways 24507:[DB01281 DB07543] DB01281|Abatacept CD80;CD86 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0007165| signal transduction ADRB2;CD86 24508:[DB01281 DB00504] DB01281|Abatacept CD80;CD86 DB00504|Levallorphan OPRM1 common genes common pathways GO:0007165| signal transduction CD86;OPRM1 24509:[DB01281 DB00413] DB01281|Abatacept CD80;CD86 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;DRD3;CD86;ADRA2A;HTR2B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0046718| entry of virus into host cell HTR2A;CD80;CD86 GO:0007165| signal transduction DRD1;DRD5;ADRA2C;HTR1A;DRD4;HTR2A;ADRA2B;HTR1D;ADRA2A;HTR2C;HTR2B;CD86;HTR1B;DRD2;DRD3 24510:[DB01281 DB03685] DB01281|Abatacept CD80;CD86 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways GO:0016032| viral reproduction CD86;UCKL1;CD80 GO:0002376| immune system process CD86;ISG20 24511:[DB01281 DB07926] DB01281|Abatacept CD80;CD86 DB07926|N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE MMP1 common genes common pathways GO:0016032| viral reproduction CD86;CD80;MMP1 24512:[DB01281 DB01179] DB01281|Abatacept CD80;CD86 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways 24513:[DB01281 DB05127] DB01281|Abatacept CD80;CD86 DB05127|ANA971 TLR7 common genes common pathways GO:0007165| signal transduction TLR7;CD86 GO:0006955| immune response CD86;TLR7 GO:0002376| immune system process CD86;TLR7 24514:[DB01281 DB03372] DB01281|Abatacept CD80;CD86 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways GO:0006955| immune response CD86;IL2 GO:0002376| immune system process CD86;IL2 GO:0002250| adaptive immune response IL2;CD86 GO:0008284| positive regulation of cell proliferation IL2;CD86 24515:[DB01281 DB01148] DB01281|Abatacept CD80;CD86 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways GO:0007165| signal transduction CD86;CHRM1;CHRM2 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 24516:[DB01281 DB01594] DB01281|Abatacept CD80;CD86 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0007165| signal transduction GABRD;GABRP;GABRR2;GABRA5;CD86;GABRE;GABRB1;GABRB3 24517:[DB01281 DB00645] DB01281|Abatacept CD80;CD86 DB00645|Dyclonine SCN10A common genes common pathways 24518:[DB01281 DB09213] DB01281|Abatacept CD80;CD86 DB09213|Dexibuprofen PTGS2;PTGS1;BCL2;THBD;PLAT;FABP2;PPARG;CFTR;SLC15A1;PPARA;GP1BA;S100A7;CYP2C9;UGT1A1;UGT1A3;UGT1A9;UGT2B4;UGT2B7;CYP2C8;CYP2C19;AMACR;ALB;ABCC4;ABCC1;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLCO2B1;ABCB1 common genes common pathways GO:0007165| signal transduction THBD;CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD80;PPARA GO:0008284| positive regulation of cell proliferation BCL2;PTGS2;CD86 24519:[DB01281 DB04863] DB01281|Abatacept CD80;CD86 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction CD80;CD86;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ITGB3 GO:0046718| entry of virus into host cell ITGB3;CD86;CD80 24520:[DB01281 DB00232] DB01281|Abatacept CD80;CD86 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways 24521:[DB01281 DB00725] DB01281|Abatacept CD80;CD86 DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;CHRM5;CHRM3;CD86;CHRM4 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 24522:[DB01281 DB00838] DB01281|Abatacept CD80;CD86 DB00838|Clocortolone NR3C1 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 24523:[DB01281 DB00196] DB01281|Abatacept CD80;CD86 DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways GO:0006955| immune response CD86;CYP11B1 24524:[DB01281 DB06935] DB01281|Abatacept CD80;CD86 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways 24525:[DB01281 DB01833] DB01281|Abatacept CD80;CD86 DB01833|L-2-Amino-4-(Guanidinooxy)Butyric Acid NOS3 common genes common pathways 24526:[DB01281 DB08911] DB01281|Abatacept CD80;CD86 DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;MAP2K2;MAP2K1 GO:0007165| signal transduction CD86;MAP2K1 24527:[DB01281 DB08128] DB01281|Abatacept CD80;CD86 DB08128|(1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine PNMT common genes common pathways 24528:[DB01281 DB06981] DB01281|Abatacept CD80;CD86 DB06981|(2S)-2-(1H-indol-3-yl)pentanoic acid SKP1 common genes common pathways 24529:[DB01281 DB01415] DB01281|Abatacept CD80;CD86 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 24530:[DB01281 DB06914] DB01281|Abatacept CD80;CD86 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0035556| intracellular signal transduction HMOX1;CD80 24531:[DB01281 DB03937] DB01281|Abatacept CD80;CD86 DB03937|Erythose-4-Phosphate kdsA;GPI common genes common pathways 24532:[DB01281 DB00940] DB01281|Abatacept CD80;CD86 DB00940|Methantheline CHRM1;HRH2 common genes common pathways GO:0007165| signal transduction CD86;CHRM1;HRH2 GO:0006955| immune response CD86;HRH2 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 24533:[DB01281 DB01837] DB01281|Abatacept CD80;CD86 DB01837|O-acetyl-L-serine PTGS1 common genes common pathways 24534:[DB01281 DB05943] DB01281|Abatacept CD80;CD86 DB05943|Resatorvid CSF2RB;IL2RG common genes common pathways GO:0006955| immune response CD86;IL2RG GO:0016032| viral reproduction CD80;IL2RG;CD86 GO:0007165| signal transduction IL2RG;CD86;CSF2RB 24535:[DB01281 DB09422] DB01281|Abatacept CD80;CD86 DB09422|Soybean oil PPARA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CD80;CD86 24536:[DB01281 DB03245] DB01281|Abatacept CD80;CD86 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways 24537:[DB01281 DB00816] DB01281|Abatacept CD80;CD86 DB00816|Orciprenaline ADRB2 common genes common pathways GO:0007165| signal transduction ADRB2;CD86 24538:[DB01281 DB01983] DB01281|Abatacept CD80;CD86 DB01983|2(S)-Amino-6-Boronohexanoic Acid ARG1 common genes common pathways GO:0002376| immune system process ARG1;CD86 GO:0002250| adaptive immune response CD86;ARG1 24539:[DB01281 DB02548] DB01281|Abatacept CD80;CD86 DB02548|D-glucitol 6-phosphate GPI common genes common pathways 24540:[DB01281 DB04185] DB01281|Abatacept CD80;CD86 DB04185|Norvaline OTC;GATM common genes common pathways 24541:[DB01281 DB01165] DB01281|Abatacept CD80;CD86 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways 24542:[DB01281 DB00671] DB01281|Abatacept CD80;CD86 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 24543:[DB01281 DB05801] DB01281|Abatacept CD80;CD86 DB05801|GTI 2040 RRM2 common genes common pathways 24544:[DB01281 DB01959] DB01281|Abatacept CD80;CD86 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways GO:0007165| signal transduction CD86;PDE4B;PDE4D 24545:[DB01281 DB01618] DB01281|Abatacept CD80;CD86 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;CHRM1;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0007165| signal transduction CD86;DRD2;CHRM1;HTR1A;HTR2A GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 24546:[DB01281 DB08894] DB01281|Abatacept CD80;CD86 DB08894|Peginesatide EPOR common genes common pathways GO:0007165| signal transduction CD86;EPOR 24547:[DB01281 DB07546] DB01281|Abatacept CD80;CD86 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways 24548:[DB01281 DB05111] DB01281|Abatacept CD80;CD86 DB05111|Fontolizumab IFNG common genes common pathways GO:0006955| immune response CD86;IFNG GO:0002250| adaptive immune response CD86;IFNG GO:0008284| positive regulation of cell proliferation CD86;IFNG 24549:[DB01281 DB03600] DB01281|Abatacept CD80;CD86 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD80 24550:[DB01281 DB01436] DB01281|Abatacept CD80;CD86 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;RXRA;CD80 GO:0007165| signal transduction VDR;CD86 GO:0016032| viral reproduction CD80;CD86;RXRA 24551:[DB01281 DB00681] DB01281|Abatacept CD80;CD86 DB00681|Amphotericin B CYP3A4 common genes common pathways 24552:[DB01281 DB09069] DB01281|Abatacept CD80;CD86 DB09069|Trimetazidine ACAA1 common genes common pathways 24553:[DB01281 DB08256] DB01281|Abatacept CD80;CD86 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways 24554:[DB01281 DB02563] DB01281|Abatacept CD80;CD86 DB02563|Hexanoyl-CoA ECHS1 common genes common pathways 24555:[DB01281 DB06233] DB01281|Abatacept CD80;CD86 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;MTOR;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;MTOR GO:0007165| signal transduction MTOR;CD86 24556:[DB01281 DB07830] DB01281|Abatacept CD80;CD86 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell DPP4;CD86;CD80 24557:[DB01281 DB12450] DB01281|Abatacept CD80;CD86 DB12450|Propyl Gallate ESR1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 GO:0007165| signal transduction ESR1;CD86 24558:[DB01281 DB08936] DB01281|Abatacept CD80;CD86 DB08936|Chlorcyclizine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 24559:[DB01281 DB04608] DB01281|Abatacept CD80;CD86 DB04608|9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE WEE1 common genes common pathways 24560:[DB01281 DB09160] DB01281|Abatacept CD80;CD86 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways 24561:[DB01281 DB12872] DB01281|Abatacept CD80;CD86 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;COL1A1;CD86 24562:[DB01281 DB00135] DB01281|Abatacept CD80;CD86 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0007165| signal transduction YARS;CD86 24563:[DB01281 DB02340] DB01281|Abatacept CD80;CD86 DB02340|N-Acetyl-Serine F13A1 common genes common pathways 24564:[DB01281 DB06477] DB01281|Abatacept CD80;CD86 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways GO:0008284| positive regulation of cell proliferation DRD3;CD86 GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD4;CD86;DRD2;DRD3 24565:[DB01281 DB02483] DB01281|Abatacept CD80;CD86 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0007165| signal transduction CD86;BST1 GO:0008284| positive regulation of cell proliferation BST1;CD86 24566:[DB01281 DB07092] DB01281|Abatacept CD80;CD86 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell DPP4;CD86;CD80 24567:[DB01281 DB00654] DB01281|Abatacept CD80;CD86 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0007165| signal transduction CD86;PTGFR GO:0008284| positive regulation of cell proliferation CD86;PTGFR 24568:[DB01281 DB07907] DB01281|Abatacept CD80;CD86 DB07907|(2S)-2-HYDROXYOCTANOIC ACID HAO1 common genes common pathways 24569:[DB01281 DB04363] DB01281|Abatacept CD80;CD86 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways 24570:[DB01281 DB07255] DB01281|Abatacept CD80;CD86 DB07255|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3-MORPHOLIN-4-YLPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways 24571:[DB01281 DB00292] DB01281|Abatacept CD80;CD86 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0006955| immune response CD86;CYP11B1 GO:0007165| signal transduction CD86;GABRA5;GABRD;GABRP;GABRB3;GABRE;GABRQ;GABRB1;GABRA6;ADRA2B 24572:[DB01281 DB00263] DB01281|Abatacept CD80;CD86 DB00263|Sulfisoxazole CYP2C9 common genes common pathways 24573:[DB01281 DB02857] DB01281|Abatacept CD80;CD86 DB02857|Guanosine PNP common genes common pathways GO:0006955| immune response CD86;PNP 24574:[DB01281 DB06660] DB01281|Abatacept CD80;CD86 DB06660|Saredutant TACR2 common genes common pathways GO:0007165| signal transduction TACR2;CD86 24575:[DB01281 DB07129] DB01281|Abatacept CD80;CD86 DB07129|(2R)-1-(2,6-dimethylphenoxy)propan-2-amine PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 24576:[DB01281 DB12836] DB01281|Abatacept CD80;CD86 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways GO:0006955| immune response CD86;PTGER4 GO:0007165| signal transduction PTGER4;CD86 24577:[DB01281 DB06281] DB01281|Abatacept CD80;CD86 DB06281|Torcetrapib CETP;CYP11B2 common genes common pathways 24578:[DB01281 DB03064] DB01281|Abatacept CD80;CD86 DB03064|3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline HAO1 common genes common pathways 24579:[DB01281 DB00139] DB01281|Abatacept CD80;CD86 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0007165| signal transduction SUCNR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ASPH;CD80 24580:[DB01281 DB02110] DB01281|Abatacept CD80;CD86 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways 24581:[DB01281 DB01854] DB01281|Abatacept CD80;CD86 DB01854|5-Bromonicotinamide ART1 common genes common pathways 24582:[DB01281 DB06156] DB01281|Abatacept CD80;CD86 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways 24583:[DB01281 DB09016] DB01281|Abatacept CD80;CD86 DB09016|Butriptyline SLC6A4;HRH1;HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0046718| entry of virus into host cell CD86;CD80;HTR2A GO:0007165| signal transduction HRH1;HTR2A;CD86 24584:[DB01281 DB01430] DB01281|Abatacept CD80;CD86 DB01430|Almitrine ATP1A1 common genes common pathways 24585:[DB01281 DB04234] DB01281|Abatacept CD80;CD86 DB04234|N2-({[(4-Bromophenyl)Methyl]Oxy}Carbonyl)-N1-[(1s)-1-Formylpentyl]-L-Leucinamide CTSK common genes common pathways 24586:[DB01281 DB06701] DB01281|Abatacept CD80;CD86 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways 24587:[DB01281 DB13164] DB01281|Abatacept CD80;CD86 DB13164|Olmutinib EGFR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;EGFR GO:0046854| phosphatidylinositol phosphorylation CD86;EGFR;CD80 GO:0035556| intracellular signal transduction EGFR;CD80 GO:0007165| signal transduction CD86;EGFR GO:0046718| entry of virus into host cell CD86;EGFR;CD80 24588:[DB01281 DB09334] DB01281|Abatacept CD80;CD86 DB09334|Seractide acetate MC2R common genes common pathways GO:0007165| signal transduction MC2R;CD86 24589:[DB01281 DB03752] DB01281|Abatacept CD80;CD86 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways 24590:[DB01281 DB04017] DB01281|Abatacept CD80;CD86 DB04017|Clorgiline MAOA common genes common pathways 24591:[DB01281 DB08291] DB01281|Abatacept CD80;CD86 DB08291|N-(3-AMINOPROPYL)-2-NITROBENZENAMINE KAT2B common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;KAT2B GO:0016032| viral reproduction CD86;KAT2B;CD80 24592:[DB01281 DB00854] DB01281|Abatacept CD80;CD86 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response OPRD1;CD86;OPRK1 GO:0007165| signal transduction CD86;OPRK1;OPRD1;OPRM1 24593:[DB01281 DB03150] DB01281|Abatacept CD80;CD86 DB03150|2',3'-Dideoxythymidine-5'-Monophosphate DTYMK common genes common pathways 24594:[DB01281 DB04614] DB01281|Abatacept CD80;CD86 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways 24595:[DB01281 DB00493] DB01281|Abatacept CD80;CD86 DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 24596:[DB01281 DB06848] DB01281|Abatacept CD80;CD86 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways 24597:[DB01281 DB08695] DB01281|Abatacept CD80;CD86 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways GO:0007165| signal transduction HPGDS;CD86 24598:[DB01281 DB00623] DB01281|Abatacept CD80;CD86 DB00623|Fluphenazine DRD2;DRD1;CALM1;AR;HTR2A;HTR2C;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0007165| signal transduction HTR2A;DRD1;AR;DRD2;CD86;HTR2C GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0008284| positive regulation of cell proliferation AR;HTR2A;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;AR;CD80 24599:[DB01281 DB14050] DB01281|Abatacept CD80;CD86 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways 24600:[DB01281 DB01245] DB01281|Abatacept CD80;CD86 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0007165| signal transduction CHRNA4;CHRNA2;CD86;CHRNB2 24601:[DB01281 DB05785] DB01281|Abatacept CD80;CD86 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0008284| positive regulation of cell proliferation RARB;CD86;JUN;RARA;RARG GO:0045893| positive regulation of transcription, DNA-dependent JUN;CD80;RARA;CD86 GO:0045630| positive regulation of T-helper 2 cell differentiation RARA;CD86 GO:0007165| signal transduction RARB;CD86;RARA 24602:[DB01281 DB02580] DB01281|Abatacept CD80;CD86 DB02580|Pentaglyme PFN2;gpmA;purA common genes common pathways 24603:[DB01281 DB08617] DB01281|Abatacept CD80;CD86 DB08617|4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE YARS common genes common pathways GO:0007165| signal transduction YARS;CD86 24604:[DB01281 DB00119] DB01281|Abatacept CD80;CD86 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways 24605:[DB01281 DB02623] DB01281|Abatacept CD80;CD86 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways GO:0031295| T cell costimulation CDC42;CD80;CD86 24606:[DB01281 DB01805] DB01281|Abatacept CD80;CD86 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways 24607:[DB01281 DB02185] DB01281|Abatacept CD80;CD86 DB02185|2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One LCTL common genes common pathways 24608:[DB01281 DB11201] DB01281|Abatacept CD80;CD86 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 24609:[DB01281 DB02418] DB01281|Abatacept CD80;CD86 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways 24610:[DB01281 DB11626] DB01281|Abatacept CD80;CD86 DB11626|Tasonermin TNFRSF1A;TNFRSF1B common genes common pathways GO:0006955| immune response TNFRSF1B;CD86;TNFRSF1A GO:0016032| viral reproduction CD80;CD86;TNFRSF1A GO:0007165| signal transduction TNFRSF1A;CD86 24611:[DB01281 DB00392] DB01281|Abatacept CD80;CD86 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CHRM2;CHRM1;CD86 24612:[DB01281 DB08632] DB01281|Abatacept CD80;CD86 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways 24613:[DB01281 DB09559] DB01281|Abatacept CD80;CD86 DB09559|Necitumumab EGFR common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;EGFR GO:0007165| signal transduction CD86;EGFR GO:0035556| intracellular signal transduction CD80;EGFR GO:0046854| phosphatidylinositol phosphorylation EGFR;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;EGFR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;EGFR GO:0008284| positive regulation of cell proliferation CD86;EGFR 24614:[DB01281 DB00775] DB01281|Abatacept CD80;CD86 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ITGB3 GO:0016032| viral reproduction CD86;ITGB3;CD80 GO:0046718| entry of virus into host cell CD80;ITGB3;CD86 24615:[DB01281 DB00483] DB01281|Abatacept CD80;CD86 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CHRM1;CHRM2;CHRM5;CHRNA2;CD86 24616:[DB01281 DB07297] DB01281|Abatacept CD80;CD86 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways GO:0031295| T cell costimulation CD86;LCK;CD80 GO:0046854| phosphatidylinositol phosphorylation LCK;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade LCK;CD86;CD80 GO:0016032| viral reproduction CD86;LCK;CD80 24617:[DB01281 DB03680] DB01281|Abatacept CD80;CD86 DB03680|Tartronate ME2;ME3 common genes common pathways 24618:[DB01281 DB00300] DB01281|Abatacept CD80;CD86 DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways 24619:[DB01281 DB00416] DB01281|Abatacept CD80;CD86 DB00416|Metocurine Iodide CHRNA2 common genes common pathways GO:0007165| signal transduction CD86;CHRNA2 24620:[DB01281 DB01914] DB01281|Abatacept CD80;CD86 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways 24621:[DB01281 DB04005] DB01281|Abatacept CD80;CD86 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways 24622:[DB01281 DB03376] DB01281|Abatacept CD80;CD86 DB03376|'5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 24623:[DB01281 DB00063] DB01281|Abatacept CD80;CD86 DB00063|Eptifibatide ITGB3 common genes common pathways GO:0046718| entry of virus into host cell CD86;ITGB3;CD80 GO:0016032| viral reproduction CD86;ITGB3;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ITGB3 24624:[DB01281 DB04917] DB01281|Abatacept CD80;CD86 DB04917|Renzapride HTR3A;HTR4 common genes common pathways GO:0007165| signal transduction HTR4;CD86;HTR3A 24625:[DB01281 DB00149] DB01281|Abatacept CD80;CD86 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways 24626:[DB01281 DB08251] DB01281|Abatacept CD80;CD86 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways GO:0035556| intracellular signal transduction CASP3;CD80 24627:[DB01281 DB03575] DB01281|Abatacept CD80;CD86 DB03575|Phencyclidine GRIN3A;SIGMAR1;CYP2B6 common genes common pathways 24628:[DB01281 DB01917] DB01281|Abatacept CD80;CD86 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways GO:0007165| signal transduction ADRB1;CD86;ADRB2 GO:0008284| positive regulation of cell proliferation CD86;ODC1 24629:[DB01281 DB03256] DB01281|Abatacept CD80;CD86 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways 24630:[DB01281 DB08486] DB01281|Abatacept CD80;CD86 DB08486|Efaproxiral HBA1;HBB common genes common pathways 24631:[DB01281 DB08302] DB01281|Abatacept CD80;CD86 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 GO:0007165| signal transduction PPARG;CD86 24632:[DB01281 DB07842] DB01281|Abatacept CD80;CD86 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;PPARG 24633:[DB01281 DB05308] DB01281|Abatacept CD80;CD86 DB05308|ANX-510 TYMS common genes common pathways 24634:[DB01281 DB04764] DB01281|Abatacept CD80;CD86 DB04764|[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE TPSB2 common genes common pathways 24635:[DB01281 DB00732] DB01281|Abatacept CD80;CD86 DB00732|Atracurium besylate CHRNA2 common genes common pathways GO:0007165| signal transduction CD86;CHRNA2 24636:[DB01281 DB07302] DB01281|Abatacept CD80;CD86 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD80 24637:[DB01281 DB02166] DB01281|Abatacept CD80;CD86 DB02166|Propidium ACHE common genes common pathways 24638:[DB01281 DB14597] DB01281|Abatacept CD80;CD86 DB14597|Lanadelumab KLKB1 common genes common pathways 24639:[DB01281 DB07047] DB01281|Abatacept CD80;CD86 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways 24640:[DB01281 DB08897] DB01281|Abatacept CD80;CD86 DB08897|Aclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;BCHE common genes common pathways GO:0007165| signal transduction CHRM5;CHRM1;CHRM2;CHRM4;CD86;CHRM3 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 24641:[DB01281 DB09517] DB01281|Abatacept CD80;CD86 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways 24642:[DB01281 DB07144] DB01281|Abatacept CD80;CD86 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 24643:[DB01281 DB04396] DB01281|Abatacept CD80;CD86 DB04396|Thiodigalactoside NCAN;LGALS1 common genes common pathways GO:0031295| T cell costimulation CD80;LGALS1;CD86 GO:0007165| signal transduction CD86;LGALS1 24644:[DB01281 DB07670] DB01281|Abatacept CD80;CD86 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways 24645:[DB01281 DB07643] DB01281|Abatacept CD80;CD86 DB07643|5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 24646:[DB01281 DB06247] DB01281|Abatacept CD80;CD86 DB06247|CX516 GRIA1 common genes common pathways GO:0007165| signal transduction CD86;GRIA1 24647:[DB01281 DB07740] DB01281|Abatacept CD80;CD86 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways 24648:[DB01281 DB02404] DB01281|Abatacept CD80;CD86 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways 24649:[DB01281 DB11753] DB01281|Abatacept CD80;CD86 DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways 24650:[DB01281 DB04469] DB01281|Abatacept CD80;CD86 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction PDE4D;CD86 24651:[DB01281 DB00595] DB01281|Abatacept CD80;CD86 DB00595|Oxytetracycline rpsI;rpsD;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 24652:[DB01281 DB06530] DB01281|Abatacept CD80;CD86 DB06530|Resiquimod TLR7;TLR8 common genes common pathways GO:0006955| immune response CD86;TLR7 GO:0007165| signal transduction CD86;TLR8;TLR7 GO:0002376| immune system process TLR7;TLR8;CD86 24653:[DB01281 DB06607] DB01281|Abatacept CD80;CD86 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways GO:0007165| signal transduction FCGR1A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD3E;CD80 GO:0006955| immune response CD86;FCGR1A;FCGR3B;FCGR3A GO:0031295| T cell costimulation CD86;CD3E;CD80 GO:0002376| immune system process FCGR2A;FCGR1A;CD86;CD3E GO:0045086| positive regulation of interleukin-2 biosynthetic process CD80;CD86;CD3E GO:0008284| positive regulation of cell proliferation CD86;EPCAM GO:0002250| adaptive immune response CD3E;CD86 24654:[DB01281 DB04801] DB01281|Abatacept CD80;CD86 DB04801|cis-Vaccenic acid PPARD common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARD;CD80;CD86 GO:0008284| positive regulation of cell proliferation PPARD;CD86 24655:[DB01281 DB05391] DB01281|Abatacept CD80;CD86 DB05391|liposomal prostaglandin E1 GP1BA common genes common pathways 24656:[DB01281 DB08192] DB01281|Abatacept CD80;CD86 DB08192|2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE SRC common genes common pathways GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process CD86;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80;CD86 GO:0007165| signal transduction CD86;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD80;SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 24657:[DB01281 DB09421] DB01281|Abatacept CD80;CD86 DB09421|Protirelin TRHR common genes common pathways GO:0007165| signal transduction TRHR;CD86 24658:[DB01281 DB07652] DB01281|Abatacept CD80;CD86 DB07652|1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE POLK;rnhA common genes common pathways 24659:[DB01281 DB00046] DB01281|Abatacept CD80;CD86 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways GO:0008284| positive regulation of cell proliferation INSR;CD86;IGF1R GO:0051897| positive regulation of protein kinase B signaling cascade CD86;INSR;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;INSR;CD80 GO:0007165| signal transduction CD86;IGF1R GO:0035556| intracellular signal transduction CD80;INSR GO:0006955| immune response IGF1R;CD86 24660:[DB01281 DB13783] DB01281|Abatacept CD80;CD86 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 24661:[DB01281 DB00800] DB01281|Abatacept CD80;CD86 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0007165| signal transduction DRD1;ADRA1B;DRD5;ADRA2B;ADRA2C;CD86;ADRA2A;ADRA1A;ADRA1D GO:0035556| intracellular signal transduction ADRA1A;CD80;ADRA1B GO:0008284| positive regulation of cell proliferation ADRA2A;CD86;ADRA1D 24662:[DB01281 DB07282] DB01281|Abatacept CD80;CD86 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways 24663:[DB01281 DB02427] DB01281|Abatacept CD80;CD86 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways 24664:[DB01281 DB06694] DB01281|Abatacept CD80;CD86 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;CD86 GO:0035556| intracellular signal transduction ADRA1A;ADRA1B;CD80 GO:0007165| signal transduction ADRA2C;ADRA2B;ADRA1B;ADRA1D;ADRA1A;ADRA2A;CD86 24665:[DB01281 DB05289] DB01281|Abatacept CD80;CD86 DB05289|Tarenflurbil IKBKG common genes common pathways GO:0016032| viral reproduction CD80;IKBKG;CD86 GO:0006955| immune response CD86;IKBKG 24666:[DB01281 DB00168] DB01281|Abatacept CD80;CD86 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0007165| signal transduction TAS1R3;TAS1R2;CD86 24667:[DB01281 DB07873] DB01281|Abatacept CD80;CD86 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways 24668:[DB01281 DB12307] DB01281|Abatacept CD80;CD86 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0008284| positive regulation of cell proliferation HGF;CD86;KDR GO:0051897| positive regulation of protein kinase B signaling cascade HGF;CD86;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;HGF GO:0016032| viral reproduction CD80;CD86;KDR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HGF 24669:[DB01281 DB11587] DB01281|Abatacept CD80;CD86 DB11587|Etafedrine ADRB2 common genes common pathways GO:0007165| signal transduction ADRB2;CD86 24670:[DB01281 DB12436] DB01281|Abatacept CD80;CD86 DB12436|Vofopitant TACR1 common genes common pathways GO:0007165| signal transduction TACR1;CD86 24671:[DB01281 DB06920] DB01281|Abatacept CD80;CD86 DB06920|Eribaxaban F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 24672:[DB01281 DB06953] DB01281|Abatacept CD80;CD86 DB06953|2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE FNTA;FNTB common genes common pathways 24673:[DB01281 DB04105] DB01281|Abatacept CD80;CD86 DB04105|N-Heptylformamide ADH1B common genes common pathways 24674:[DB01281 DB05407] DB01281|Abatacept CD80;CD86 DB05407|TBC-3711 EDN1 common genes common pathways GO:0035556| intracellular signal transduction EDN1;CD80 GO:0008284| positive regulation of cell proliferation CD86;EDN1 24675:[DB01281 DB12555] DB01281|Abatacept CD80;CD86 DB12555|Nelotanserin HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HTR2A GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0007165| signal transduction CD86;HTR2A 24676:[DB01281 DB06469] DB01281|Abatacept CD80;CD86 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation FLT3;CD86 24677:[DB01281 DB06741] DB01281|Abatacept CD80;CD86 DB06741|Gavestinel GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;UGT1A1;UGT1A3;UGT1A9;UGT2B4 common genes common pathways 24678:[DB01281 DB08655] DB01281|Abatacept CD80;CD86 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CREBBP;CD86 GO:0016032| viral reproduction CREBBP;CD86;CD80 GO:0007165| signal transduction CD86;CREBBP 24679:[DB01281 DB02360] DB01281|Abatacept CD80;CD86 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways GO:0006955| immune response CD86;CTSG 24680:[DB01281 DB01866] DB01281|Abatacept CD80;CD86 DB01866|RU79256 SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;SRC GO:0002376| immune system process SRC;CD86 GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction SRC;CD80;CD86 GO:0007165| signal transduction CD86;SRC 24681:[DB01281 DB07053] DB01281|Abatacept CD80;CD86 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARG;CD86 24682:[DB01281 DB07265] DB01281|Abatacept CD80;CD86 DB07265|3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID WEE1 common genes common pathways 24683:[DB01281 DB07450] DB01281|Abatacept CD80;CD86 DB07450|(R)-minalrestat AKR1B1 common genes common pathways 24684:[DB01281 DB04942] DB01281|Abatacept CD80;CD86 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways GO:0007165| signal transduction RARB;CD86;CRABP1;RARA GO:0008284| positive regulation of cell proliferation CD86;RARB;RARA GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;RARA GO:0045630| positive regulation of T-helper 2 cell differentiation CD86;RARA 24685:[DB01281 DB00735] DB01281|Abatacept CD80;CD86 DB00735|Naftifine SQLE common genes common pathways 24686:[DB01281 DB02846] DB01281|Abatacept CD80;CD86 DB02846|L-thioproline ANXA5 common genes common pathways GO:0007165| signal transduction CD86;ANXA5 24687:[DB01281 DB03673] DB01281|Abatacept CD80;CD86 DB03673|Beta(2-Thienyl)Alanine PAH common genes common pathways 24688:[DB01281 DB04867] DB01281|Abatacept CD80;CD86 DB04867|Lintitript CCKAR common genes common pathways GO:0007165| signal transduction CCKAR;CD86 24689:[DB01281 DB00770] DB01281|Abatacept CD80;CD86 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0007165| signal transduction CD86;PTGER1;PTGER2;PTGDR2 GO:0006955| immune response PTGDR2;CD86 24690:[DB01281 DB05956] DB01281|Abatacept CD80;CD86 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0016032| viral reproduction RXRA;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;RXRA;CD86 24691:[DB01281 DB04967] DB01281|Abatacept CD80;CD86 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0016032| viral reproduction TOP1;CD80;CD86 24692:[DB01281 DB07422] DB01281|Abatacept CD80;CD86 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;AR;CD80 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0007165| signal transduction AR;CD86 24693:[DB01281 DB07205] DB01281|Abatacept CD80;CD86 DB07205|N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE YARS common genes common pathways GO:0007165| signal transduction YARS;CD86 24694:[DB01281 DB06094] DB01281|Abatacept CD80;CD86 DB06094|Apatorsen HSPB1 common genes common pathways GO:0035556| intracellular signal transduction HSPB1;CD80 24695:[DB01281 DB05390] DB01281|Abatacept CD80;CD86 DB05390|INS 316 P2RY2 common genes common pathways GO:0007165| signal transduction P2RY2;CD86 24696:[DB01281 DB04974] DB01281|Abatacept CD80;CD86 DB04974|AP1903 MTOR common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;MTOR GO:0007165| signal transduction MTOR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;MTOR;CD80 24697:[DB01281 DB00417] DB01281|Abatacept CD80;CD86 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 24698:[DB01281 DB02234] DB01281|Abatacept CD80;CD86 DB02234|S-Ethylisothiourea NOS2;NOS3 common genes common pathways 24699:[DB01281 DB11691] DB01281|Abatacept CD80;CD86 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0007165| signal transduction CD86;OPRK1;OPRD1;OPRM1 GO:0006955| immune response OPRD1;CD86;OPRK1 24700:[DB01281 DB04471] DB01281|Abatacept CD80;CD86 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 GO:0007165| signal transduction ESR1;CD86 24701:[DB01281 DB08045] DB01281|Abatacept CD80;CD86 DB08045|4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL HSP90AB1 common genes common pathways 24702:[DB01281 DB06885] DB01281|Abatacept CD80;CD86 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways 24703:[DB01281 DB02263] DB01281|Abatacept CD80;CD86 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways 24704:[DB01281 DB03072] DB01281|Abatacept CD80;CD86 DB03072|2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone PARP1 common genes common pathways 24705:[DB01281 DB06311] DB01281|Abatacept CD80;CD86 DB06311|Darapladib PLA2G4A common genes common pathways 24706:[DB01281 DB02696] DB01281|Abatacept CD80;CD86 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways 24707:[DB01281 DB08121] DB01281|Abatacept CD80;CD86 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARG;CD86 24708:[DB01281 DB03192] DB01281|Abatacept CD80;CD86 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways 24709:[DB01281 DB14515] DB01281|Abatacept CD80;CD86 DB14515|Magnesium lactate ATP1A1 common genes common pathways 24710:[DB01281 DB06985] DB01281|Abatacept CD80;CD86 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways 24711:[DB01281 DB03405] DB01281|Abatacept CD80;CD86 DB03405|N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide CTSK common genes common pathways 24712:[DB01281 DB11157] DB01281|Abatacept CD80;CD86 DB11157|Anthralin KRT2;MAPK8IP1;KRT12 common genes common pathways GO:0007165| signal transduction MAPK8IP1;CD86 24713:[DB01281 DB08550] DB01281|Abatacept CD80;CD86 DB08550|7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline PNMT common genes common pathways 24714:[DB01281 DB03267] DB01281|Abatacept CD80;CD86 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 24715:[DB01281 DB00536] DB01281|Abatacept CD80;CD86 DB00536|Guanidine argG;GAMT;RNASE1;DLG4;ALDH2;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A8;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0007165| signal transduction DLG4;CD86 24716:[DB01281 DB12569] DB01281|Abatacept CD80;CD86 DB12569|Tonapofylline ADORA1 common genes common pathways GO:0007165| signal transduction ADORA1;CD86 24717:[DB01281 DB00882] DB01281|Abatacept CD80;CD86 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 GO:0007165| signal transduction CD86;ESR1 24718:[DB01281 DB09224] DB01281|Abatacept CD80;CD86 DB09224|Melperone DRD2;CYP2D6 common genes common pathways GO:0007165| signal transduction DRD2;CD86 GO:0035556| intracellular signal transduction DRD2;CD80 24719:[DB01281 DB03882] DB01281|Abatacept CD80;CD86 DB03882|5-Alpha-Androstane-3-Beta,17beta-Diol ESR2;SHBG common genes common pathways GO:0007165| signal transduction ESR2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;CD80 24720:[DB01281 DB07234] DB01281|Abatacept CD80;CD86 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways 24721:[DB01281 DB05284] DB01281|Abatacept CD80;CD86 DB05284|CA4P TUBB common genes common pathways 24722:[DB01281 DB08498] DB01281|Abatacept CD80;CD86 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0035556| intracellular signal transduction CASP3;CD80 24723:[DB01281 DB01969] DB01281|Abatacept CD80;CD86 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 24724:[DB01281 DB00172] DB01281|Abatacept CD80;CD86 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0016032| viral reproduction PPIA;CD86;CD80 24725:[DB01281 DB01989] DB01281|Abatacept CD80;CD86 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways 24726:[DB01281 DB00269] DB01281|Abatacept CD80;CD86 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 24727:[DB01281 DB07906] DB01281|Abatacept CD80;CD86 DB07906|[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL PNMT common genes common pathways 24728:[DB01281 DB02419] DB01281|Abatacept CD80;CD86 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways GO:0016032| viral reproduction PPIA;CD86;CD80 24729:[DB01281 DB12128] DB01281|Abatacept CD80;CD86 DB12128|Ulimorelin GHSR common genes common pathways GO:0007165| signal transduction CD86;GHSR 24730:[DB01281 DB07405] DB01281|Abatacept CD80;CD86 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways 24731:[DB01281 DB08746] DB01281|Abatacept CD80;CD86 DB08746|1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 24732:[DB01281 DB00711] DB01281|Abatacept CD80;CD86 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways 24733:[DB01281 DB01326] DB01281|Abatacept CD80;CD86 DB01326|Cefamandole SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 24734:[DB01281 DB07627] DB01281|Abatacept CD80;CD86 DB07627|(2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPN1;CD86 24735:[DB01281 DB05420] DB01281|Abatacept CD80;CD86 DB05420|Gallium maltolate RRM1 common genes common pathways 24736:[DB01281 DB03187] DB01281|Abatacept CD80;CD86 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 24737:[DB01281 DB07329] DB01281|Abatacept CD80;CD86 DB07329|1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID IGHG2 common genes common pathways GO:0002376| immune system process IGHG2;CD86 GO:0002250| adaptive immune response IGHG2;CD86 24738:[DB01281 DB05798] DB01281|Abatacept CD80;CD86 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways GO:0035556| intracellular signal transduction PRKAR1A;PRKAR2A;CD80 24739:[DB01281 DB05533] DB01281|Abatacept CD80;CD86 DB05533|QR-333 AKR1B1 common genes common pathways 24740:[DB01281 DB07733] DB01281|Abatacept CD80;CD86 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways GO:0007165| signal transduction CASP1;CD86 24741:[DB01281 DB14012] DB01281|Abatacept CD80;CD86 DB14012|Burosumab FGF23 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;FGF23;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;FGF23;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;FGF23 24742:[DB01281 DB07978] DB01281|Abatacept CD80;CD86 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways 24743:[DB01281 DB08735] DB01281|Abatacept CD80;CD86 DB08735|R,S-Warfarin alcohol ALB common genes common pathways 24744:[DB01281 DB11300] DB01281|Abatacept CD80;CD86 DB11300|Thrombin F2R;F2RL3;F11;F13A1;F13B;FGA;FGB;FGG;F5;F8 common genes common pathways GO:0002376| immune system process FGB;CD86;FGA GO:0045893| positive regulation of transcription, DNA-dependent F2R;CD80;CD86 GO:0002250| adaptive immune response FGB;FGA;CD86 GO:0008284| positive regulation of cell proliferation F2R;CD86 GO:0007165| signal transduction CD86;FGA;F2RL3;FGG;FGB;F2R 24745:[DB01281 DB05025] DB01281|Abatacept CD80;CD86 DB05025|Arimoclomol SOD1 common genes common pathways 24746:[DB01281 DB06824] DB01281|Abatacept CD80;CD86 DB06824|Triethylenetetramine GPC1 common genes common pathways 24747:[DB01281 DB06245] DB01281|Abatacept CD80;CD86 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways GO:0016032| viral reproduction KRT8;CD80;CD86 GO:0007165| signal transduction CD86;FGA;PLAUR GO:0002250| adaptive immune response CD86;FGA GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 GO:0008284| positive regulation of cell proliferation CD86;FN1;CALR GO:0002376| immune system process CD86;FGA 24748:[DB01281 DB02510] DB01281|Abatacept CD80;CD86 DB02510|'5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 24749:[DB01281 DB05424] DB01281|Abatacept CD80;CD86 DB05424|Canertinib EGFR common genes common pathways GO:0007165| signal transduction EGFR;CD86 GO:0046718| entry of virus into host cell CD80;CD86;EGFR GO:0035556| intracellular signal transduction EGFR;CD80 GO:0046854| phosphatidylinositol phosphorylation EGFR;CD86;CD80 GO:0008284| positive regulation of cell proliferation EGFR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;EGFR GO:0045893| positive regulation of transcription, DNA-dependent CD80;EGFR;CD86 24750:[DB01281 DB05219] DB01281|Abatacept CD80;CD86 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes common pathways GO:0007165| signal transduction PDE4D;PDE4A;CD86;PDE4B;PDE4C 24751:[DB01281 DB00890] DB01281|Abatacept CD80;CD86 DB00890|Dienestrol ESR1;SHBG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 GO:0007165| signal transduction CD86;ESR1 24752:[DB01281 DB05469] DB01281|Abatacept CD80;CD86 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0007165| signal transduction ADRA1B;ADRA1A;CD86;ADRA1D GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0008284| positive regulation of cell proliferation CD86;ADRA1D 24753:[DB01281 DB00991] DB01281|Abatacept CD80;CD86 DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 24754:[DB01281 DB03003] DB01281|Abatacept CD80;CD86 DB03003|Glutathione Sulfonic Acid gstA;GSTM4;GSTA1;GSTP1 common genes common pathways 24755:[DB01281 DB02750] DB01281|Abatacept CD80;CD86 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 24756:[DB01281 DB11638] DB01281|Abatacept CD80;CD86 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0007165| signal transduction LGALS1;CLIC1;ZYX;CD86;DPYSL2;IQGAP1;NPM1;HNRNPK GO:0035556| intracellular signal transduction HSPB1;CD80 GO:0016032| viral reproduction VIM;CD80;ZYX;CD86;HSPA8;NPM1;PPIA;HNRNPK GO:0031295| T cell costimulation CD86;CD80;LGALS1 GO:0002376| immune system process SFPQ;CD86 GO:0008284| positive regulation of cell proliferation NPM1;SHMT2;CD86;RPS9 GO:0045893| positive regulation of transcription, DNA-dependent HNRNPD;CD80;CD86;NPM1 24757:[DB01281 DB01161] DB01281|Abatacept CD80;CD86 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0007165| signal transduction CHRNA10;HTR3A;CD86 24758:[DB01281 DB01870] DB01281|Abatacept CD80;CD86 DB01870|1,4-dithio-alpha-D-glucopyranose AMY2B common genes common pathways 24759:[DB01281 DB07374] DB01281|Abatacept CD80;CD86 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0008284| positive regulation of cell proliferation RPL23;CD86 24760:[DB01281 DB04882] DB01281|Abatacept CD80;CD86 DB04882|Edotecarin TOP1 common genes common pathways GO:0016032| viral reproduction CD86;CD80;TOP1 24761:[DB01281 DB14637] DB01281|Abatacept CD80;CD86 DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways 24762:[DB01281 DB06451] DB01281|Abatacept CD80;CD86 DB06451|Aprinocarsen PRKCA common genes common pathways GO:0035556| intracellular signal transduction CD80;PRKCA 24763:[DB01281 DB07207] DB01281|Abatacept CD80;CD86 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F7;CD80;F3 24764:[DB01281 DB08547] DB01281|Abatacept CD80;CD86 DB08547|PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0002250| adaptive immune response CD86;IGHG2 GO:0002376| immune system process IGHG2;CD86 24765:[DB01281 DB07488] DB01281|Abatacept CD80;CD86 DB07488|{(2Z)-4-AMINO-2-[(4-METHOXYPHENYL)IMINO]-2,3-DIHYDRO-1,3-THIAZOL-5-YL}(4-METHOXYPHENYL)METHANONE CSNK1G3 common genes common pathways GO:0007165| signal transduction CD86;CSNK1G3 24766:[DB01281 DB00663] DB01281|Abatacept CD80;CD86 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 24767:[DB01281 DB00801] DB01281|Abatacept CD80;CD86 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRD;GABRP;GABRR2;GABRA5;CD86;GABRA6;GABRE;GABRQ;GABRB1;GABRB3 24768:[DB01281 DB01282] DB01281|Abatacept CD80;CD86 DB01282|Carbetocin OXTR common genes common pathways GO:0007165| signal transduction OXTR;CD86 24769:[DB01281 DB01143] DB01281|Abatacept CD80;CD86 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways GO:0006955| immune response CD86;ENPP1 24770:[DB01281 DB02715] DB01281|Abatacept CD80;CD86 DB02715|Compound 18 ESR1 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 24771:[DB01281 DB00226] DB01281|Abatacept CD80;CD86 DB00226|Guanadrel SLC6A2 common genes common pathways 24772:[DB01281 DB01373] DB01281|Abatacept CD80;CD86 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0007165| signal transduction CD86;ATP2C1 GO:0002376| immune system process CD86;S100A8;S100A9 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;BMP4 GO:0008284| positive regulation of cell proliferation S100B;S100A13;CD86;BMP4 24773:[DB01281 DB01321] DB01281|Abatacept CD80;CD86 DB01321|Josamycin rplD;CYP3A4 common genes common pathways 24774:[DB01281 DB01915] DB01281|Abatacept CD80;CD86 DB01915|S-Hydroxycysteine C3;GSTP1;ACAT2;GSTA1;PMP2 common genes common pathways GO:0007165| signal transduction C3;CD86 GO:0006955| immune response C3;CD86 GO:0002376| immune system process C3;CD86 24775:[DB01281 DB07593] DB01281|Abatacept CD80;CD86 DB07593|1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE CTSK common genes common pathways 24776:[DB01281 DB08361] DB01281|Abatacept CD80;CD86 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process SYK;CD80 GO:0002250| adaptive immune response CD86;SYK GO:0002376| immune system process SYK;CD86 GO:0035556| intracellular signal transduction SYK;CD80 GO:0016032| viral reproduction CD80;CD86;SYK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SYK 24777:[DB01281 DB11136] DB01281|Abatacept CD80;CD86 DB11136|Chromium CYB5A;TF common genes common pathways 24778:[DB01281 DB07159] DB01281|Abatacept CD80;CD86 DB07159|Tamatinib SYK common genes common pathways GO:0002250| adaptive immune response CD86;SYK GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process CD80;SYK GO:0002376| immune system process CD86;SYK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SYK;CD80 GO:0016032| viral reproduction CD80;CD86;SYK GO:0035556| intracellular signal transduction CD80;SYK 24779:[DB01281 DB09209] DB01281|Abatacept CD80;CD86 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;OPRK1;CD86 GO:0006955| immune response OPRD1;CD86;OPRK1 24780:[DB01281 DB00114] DB01281|Abatacept CD80;CD86 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0008284| positive regulation of cell proliferation SHMT2;CD86;ODC1 24781:[DB01281 DB02931] DB01281|Abatacept CD80;CD86 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways 24782:[DB01281 DB05513] DB01281|Abatacept CD80;CD86 DB05513|Atiprimod IL6;TNF common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;CD80 GO:0006955| immune response TNF;IL6;CD86 GO:0008284| positive regulation of cell proliferation IL6;CD86 GO:0045893| positive regulation of transcription, DNA-dependent IL6;CD86;TNF;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 24783:[DB01281 DB11091] DB01281|Abatacept CD80;CD86 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;GPX1 24784:[DB01281 DB13153] DB01281|Abatacept CD80;CD86 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways 24785:[DB01281 DB08340] DB01281|Abatacept CD80;CD86 DB08340|N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE CSNK2A1 common genes common pathways GO:0007165| signal transduction CSNK2A1;CD86 GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 24786:[DB01281 DB11640] DB01281|Abatacept CD80;CD86 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways 24787:[DB01281 DB08270] DB01281|Abatacept CD80;CD86 DB08270|N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE CTSK common genes common pathways 24788:[DB01281 DB02860] DB01281|Abatacept CD80;CD86 DB02860|Calyculin A PPP1CC common genes common pathways 24789:[DB01281 DB00020] DB01281|Abatacept CD80;CD86 DB00020|Sargramostim CSF2RA;IL3RA;CSF2RB;SDC2;PRG2 common genes common pathways GO:0002376| immune system process CD86;PRG2 GO:0007165| signal transduction CSF2RB;CD86 GO:0006955| immune response PRG2;CD86 24790:[DB01281 DB03193] DB01281|Abatacept CD80;CD86 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;PPARA 24791:[DB01281 DB02258] DB01281|Abatacept CD80;CD86 DB02258|SR11254 RARG common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CD86 24792:[DB01281 DB11569] DB01281|Abatacept CD80;CD86 DB11569|Ixekizumab IL17A common genes common pathways GO:0006955| immune response IL17A;CD86 24793:[DB01281 DB01032] DB01281|Abatacept CD80;CD86 DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0016032| viral reproduction CD80;SLC10A1;CD86 GO:0046718| entry of virus into host cell CD80;SLC10A1;CD86 GO:0007165| signal transduction TAS2R16;CD86 24794:[DB01281 DB06345] DB01281|Abatacept CD80;CD86 DB06345|AR-9281 EPHX2 common genes common pathways 24795:[DB01281 DB08738] DB01281|Abatacept CD80;CD86 DB08738|1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one PREP common genes common pathways 24796:[DB01281 DB01130] DB01281|Abatacept CD80;CD86 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 24797:[DB01281 DB06151] DB01281|Abatacept CD80;CD86 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0006955| immune response CHUK;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CHUK;CD80;IKBKB 24798:[DB01281 DB07125] DB01281|Abatacept CD80;CD86 DB07125|4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid DAPK3 common genes common pathways GO:0035556| intracellular signal transduction DAPK3;CD80 24799:[DB01281 DB03704] DB01281|Abatacept CD80;CD86 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways 24800:[DB01281 DB06634] DB01281|Abatacept CD80;CD86 DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0007165| signal transduction TACR1;CD86 24801:[DB01281 DB05024] DB01281|Abatacept CD80;CD86 DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0007165| signal transduction VDR;CD86 24802:[DB01281 DB09488] DB01281|Abatacept CD80;CD86 DB09488|Acrivastine HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 24803:[DB01281 DB08869] DB01281|Abatacept CD80;CD86 DB08869|Tesamorelin GHRHR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;GHRHR GO:0007165| signal transduction CD86;GHRHR 24804:[DB01281 DB08676] DB01281|Abatacept CD80;CD86 DB08676|(20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways 24805:[DB01281 DB03509] DB01281|Abatacept CD80;CD86 DB03509|2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide PARP1 common genes common pathways 24806:[DB01281 DB00400] DB01281|Abatacept CD80;CD86 DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways 24807:[DB01281 DB07465] DB01281|Abatacept CD80;CD86 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 24808:[DB01281 DB03507] DB01281|Abatacept CD80;CD86 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways GO:0016032| viral reproduction TNFRSF1A;CD86;CD80 GO:0006955| immune response TNFRSF1A;CD86 GO:0007165| signal transduction TNFRSF1A;CD86 24809:[DB01281 DB07662] DB01281|Abatacept CD80;CD86 DB07662|N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE SRC;EGFR common genes common pathways GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation SRC;CD80;CD86 GO:0046854| phosphatidylinositol phosphorylation EGFR;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80;CD86;EGFR GO:0045893| positive regulation of transcription, DNA-dependent CD86;EGFR;SRC;CD80 GO:0007165| signal transduction EGFR;CD86;SRC GO:0046718| entry of virus into host cell CD86;EGFR;CD80 GO:0035556| intracellular signal transduction EGFR;CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction SRC;CD80;CD86 24810:[DB01281 DB06422] DB01281|Abatacept CD80;CD86 DB06422|Ticalopride HTR4;HTR3A common genes common pathways GO:0007165| signal transduction HTR3A;CD86;HTR4 24811:[DB01281 DB05869] DB01281|Abatacept CD80;CD86 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways GO:0006955| immune response CD86;TNF GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;TNF GO:0002250| adaptive immune response CD86;HMGB1 GO:0045893| positive regulation of transcription, DNA-dependent TNF;CD86;CD80 GO:0002376| immune system process CD86;HMGB1 24812:[DB01281 DB01629] DB01281|Abatacept CD80;CD86 DB01629|5-Fluorouridine SOD1 common genes common pathways 24813:[DB01281 DB12478] DB01281|Abatacept CD80;CD86 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0007165| signal transduction DRD3;DRD2;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;CD86 24814:[DB01281 DB02936] DB01281|Abatacept CD80;CD86 DB02936|4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid PLA2G2A common genes common pathways 24815:[DB01281 DB02335] DB01281|Abatacept CD80;CD86 DB02335|2-Aminothiazoline NOS3 common genes common pathways 24816:[DB01281 DB07387] DB01281|Abatacept CD80;CD86 DB07387|3-(BUTYLSULPHONYL)-PROPANOIC ACID TPI1 common genes common pathways 24817:[DB01281 DB01021] DB01281|Abatacept CD80;CD86 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways 24818:[DB01281 DB00824] DB01281|Abatacept CD80;CD86 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0007165| signal transduction ADORA1;ADORA2A;ADORA3;ADORA2B;PDE4B;CD86;PDE4A 24819:[DB01281 DB11834] DB01281|Abatacept CD80;CD86 DB11834|Guselkumab IL23A common genes common pathways GO:0002376| immune system process CD86;IL23A GO:0006955| immune response IL23A;CD86 24820:[DB01281 DB00848] DB01281|Abatacept CD80;CD86 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways GO:0007165| signal transduction CHRNA3;CD86 24821:[DB01281 DB04947] DB01281|Abatacept CD80;CD86 DB04947|Altropane SLC6A3 common genes common pathways 24822:[DB01281 DB01860] DB01281|Abatacept CD80;CD86 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 24823:[DB01281 DB04080] DB01281|Abatacept CD80;CD86 DB04080|RU78191 SRC common genes common pathways GO:0007165| signal transduction SRC;CD86 GO:0035556| intracellular signal transduction CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD86;CD80;SRC GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;SRC;CD86 24824:[DB01281 DB02917] DB01281|Abatacept CD80;CD86 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways 24825:[DB01281 DB11124] DB01281|Abatacept CD80;CD86 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0007165| signal transduction ADRA1B;ADRA2C;ADRB2;ADRA2B;ADRA1A;ADRB1;ADRA2A;ADRB3;CD86;ADRA1D GO:0008284| positive regulation of cell proliferation ADRA1D;CD86;ADRA2A 24826:[DB01281 DB02226] DB01281|Abatacept CD80;CD86 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 24827:[DB01281 DB09018] DB01281|Abatacept CD80;CD86 DB09018|Bromopride DRD2 common genes common pathways GO:0007165| signal transduction DRD2;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 24828:[DB01281 DB01096] DB01281|Abatacept CD80;CD86 DB01096|Oxamniquine CYP2D6 common genes common pathways 24829:[DB01281 DB06587] DB01281|Abatacept CD80;CD86 DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways GO:0007165| signal transduction MLNR;CD86 24830:[DB01281 DB05990] DB01281|Abatacept CD80;CD86 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0002376| immune system process NR1H4;CD86 GO:0007165| signal transduction CD86;NR1H4 24831:[DB01281 DB06061] DB01281|Abatacept CD80;CD86 DB06061|AZD-8330 MAP3K1 common genes common pathways 24832:[DB01281 DB05797] DB01281|Abatacept CD80;CD86 DB05797|TNX-901 FCER1A common genes common pathways 24833:[DB01281 DB07402] DB01281|Abatacept CD80;CD86 DB07402|Azapropazone ALB common genes common pathways 24834:[DB01281 DB04700] DB01281|Abatacept CD80;CD86 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways 24835:[DB01281 DB04593] DB01281|Abatacept CD80;CD86 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F7;CD86 24836:[DB01281 DB08054] DB01281|Abatacept CD80;CD86 DB08054|1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0007165| signal transduction SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction CD86;SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0002376| immune system process SRC;CD86 GO:0031295| T cell costimulation SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 24837:[DB01281 DB03082] DB01281|Abatacept CD80;CD86 DB03082|6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 24838:[DB01281 DB02209] DB01281|Abatacept CD80;CD86 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0008284| positive regulation of cell proliferation ODC1;CD86 24839:[DB01281 DB05088] DB01281|Abatacept CD80;CD86 DB05088|Tiomolibdate ion APP common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;APP;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP 24840:[DB01281 DB09241] DB01281|Abatacept CD80;CD86 DB09241|Methylene blue GUCY1A2;NOS1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;NOS1;CD86 GO:0007165| signal transduction GUCY1A2;CD86 GO:0035556| intracellular signal transduction CD80;GUCY1A2 24841:[DB01281 DB04351] DB01281|Abatacept CD80;CD86 DB04351|Aconitate Ion ACO2 common genes common pathways 24842:[DB01281 DB08590] DB01281|Abatacept CD80;CD86 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways GO:0007165| signal transduction IRAK4;CD86 GO:0002376| immune system process CD86;IRAK4 24843:[DB01281 DB05749] DB01281|Abatacept CD80;CD86 DB05749|MPI-674 CYP19A1 common genes common pathways 24844:[DB01281 DB09363] DB01281|Abatacept CD80;CD86 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways 24845:[DB01281 DB04888] DB01281|Abatacept CD80;CD86 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction CD86;DRD2;HTR1A GO:0008284| positive regulation of cell proliferation CD86;HTR1A 24846:[DB01281 DB01858] DB01281|Abatacept CD80;CD86 DB01858|[1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate CTSK common genes common pathways 24847:[DB01281 DB14010] DB01281|Abatacept CD80;CD86 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0007165| signal transduction CD86;HTR2A;HTR1A GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0008284| positive regulation of cell proliferation CD86;HTR1A;HTR2A 24848:[DB01281 DB01256] DB01281|Abatacept CD80;CD86 DB01256|Retapamulin rplC;CYP3A4 common genes common pathways 24849:[DB01281 DB00944] DB01281|Abatacept CD80;CD86 DB00944|Demecarium ACHE;BCHE common genes common pathways 24850:[DB01281 DB14509] DB01281|Abatacept CD80;CD86 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation CD80;IMPA2;CD86;IMPA1 GO:0035556| intracellular signal transduction CD80;GSK3B GO:0007165| signal transduction IMPA2;IMPA1;CD86 24851:[DB01281 DB04345] DB01281|Abatacept CD80;CD86 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways 24852:[DB01281 DB04836] DB01281|Abatacept CD80;CD86 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways 24853:[DB01281 DB13192] DB01281|Abatacept CD80;CD86 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 24854:[DB01281 DB00211] DB01281|Abatacept CD80;CD86 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0007165| signal transduction ADRA1B;ADRA1A;CD86;ADRA1D GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0008284| positive regulation of cell proliferation CD86;ADRA1D 24855:[DB01281 DB01564] DB01281|Abatacept CD80;CD86 DB01564|Calusterone AR common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 24856:[DB01281 DB01324] DB01281|Abatacept CD80;CD86 DB01324|Polythiazide SLC12A3 common genes common pathways 24857:[DB01281 DB03058] DB01281|Abatacept CD80;CD86 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways GO:0002376| immune system process CFD;CD86 24858:[DB01281 DB05005] DB01281|Abatacept CD80;CD86 DB05005|CCX282 CCR9 common genes common pathways GO:0007165| signal transduction CD86;CCR9 GO:0006955| immune response CCR9;CD86 24859:[DB01281 DB08008] DB01281|Abatacept CD80;CD86 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways 24860:[DB01281 DB08063] DB01281|Abatacept CD80;CD86 DB08063|1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE RXRA;NR1H3 common genes common pathways GO:0016032| viral reproduction CD80;CD86;RXRA GO:0045893| positive regulation of transcription, DNA-dependent CD80;RXRA;CD86;NR1H3 24861:[DB01281 DB01754] DB01281|Abatacept CD80;CD86 DB01754|3,4-Dihydroxy-1-Methylquinolin-2(1h)-One PIM1 common genes common pathways 24862:[DB01281 DB03686] DB01281|Abatacept CD80;CD86 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways 24863:[DB01281 DB03309] DB01281|Abatacept CD80;CD86 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways 24864:[DB01281 DB08118] DB01281|Abatacept CD80;CD86 DB08118|2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 24865:[DB01281 DB04003] DB01281|Abatacept CD80;CD86 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways GO:0016032| viral reproduction CD86;LCK;CD80 GO:0031295| T cell costimulation CD86;LCK;CD80 GO:0046854| phosphatidylinositol phosphorylation CD86;LCK;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;LCK 24866:[DB01281 DB04767] DB01281|Abatacept CD80;CD86 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F7;CD80 24867:[DB01281 DB07195] DB01281|Abatacept CD80;CD86 DB07195|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 GO:0007165| signal transduction ESR1;CD86 24868:[DB01281 DB08430] DB01281|Abatacept CD80;CD86 DB08430|PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE LCTL common genes common pathways 24869:[DB01281 DB11127] DB01281|Abatacept CD80;CD86 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;GPX1;CD86 GO:0007165| signal transduction CD86;TXNRD1 24870:[DB01281 DB03429] DB01281|Abatacept CD80;CD86 DB03429|Cardiolipin SLC25A4 common genes common pathways GO:0016032| viral reproduction SLC25A4;CD86;CD80 24871:[DB01281 DB04417] DB01281|Abatacept CD80;CD86 DB04417|P-Nitrophenol SULT1A1;AMY2B common genes common pathways 24872:[DB01281 DB08826] DB01281|Abatacept CD80;CD86 DB08826|Deferiprone UGT1A6 common genes common pathways 24873:[DB01281 DB08588] DB01281|Abatacept CD80;CD86 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;DPP4;CD86 24874:[DB01281 DB01205] DB01281|Abatacept CD80;CD86 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRB1;GABRQ;GABRE;GABRA6;GABRB3;GABRA5;GABRP;GABRD;CD86 24875:[DB01281 DB09185] DB01281|Abatacept CD80;CD86 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways 24876:[DB01281 DB08504] DB01281|Abatacept CD80;CD86 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 24877:[DB01281 DB03696] DB01281|Abatacept CD80;CD86 DB03696|Lanosterol LSS common genes common pathways 24878:[DB01281 DB06013] DB01281|Abatacept CD80;CD86 DB06013|Aldoxorubicin TOP2A common genes common pathways 24879:[DB01281 DB05968] DB01281|Abatacept CD80;CD86 DB05968|PR-104 TNF common genes common pathways GO:0006955| immune response TNF;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;TNF GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 24880:[DB01281 DB14004] DB01281|Abatacept CD80;CD86 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0002376| immune system process CD86;IL23A GO:0006955| immune response CD86;IL23A 24881:[DB01281 DB09148] DB01281|Abatacept CD80;CD86 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;APP 24882:[DB01281 DB02401] DB01281|Abatacept CD80;CD86 DB02401|4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid LDHB common genes common pathways 24883:[DB01281 DB03167] DB01281|Abatacept CD80;CD86 DB03167|Pentabromophenol TTR common genes common pathways 24884:[DB01281 DB05786] DB01281|Abatacept CD80;CD86 DB05786|Irofulven FUBP1 common genes common pathways 24885:[DB01281 DB00407] DB01281|Abatacept CD80;CD86 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 24886:[DB01281 DB02279] DB01281|Abatacept CD80;CD86 DB02279|Benzoylformic Acid HAO1 common genes common pathways 24887:[DB01281 DB08338] DB01281|Abatacept CD80;CD86 DB08338|19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one CSNK2A1 common genes common pathways GO:0007165| signal transduction CD86;CSNK2A1 GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 24888:[DB01281 DB00966] DB01281|Abatacept CD80;CD86 DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 GO:0007165| signal transduction AGTR1;CD86;PPARG 24889:[DB01281 DB04172] DB01281|Abatacept CD80;CD86 DB04172|[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 24890:[DB01281 DB06907] DB01281|Abatacept CD80;CD86 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways 24891:[DB01281 DB04217] DB01281|Abatacept CD80;CD86 DB04217|L-2-amino-3-butynoic acid CTH;sufS common genes common pathways 24892:[DB01281 DB05014] DB01281|Abatacept CD80;CD86 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;CD86;FGFR3;PDGFRB;FLT3;FGFR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;RET GO:0051897| positive regulation of protein kinase B signaling cascade FGFR1;CD80;CD86;PDGFRB;FGFR3 GO:0046854| phosphatidylinositol phosphorylation CD86;FGFR3;PDGFRB;CD80;FGFR1 GO:0035556| intracellular signal transduction CD80;PDGFRB GO:0016032| viral reproduction KDR;CD86;CD80 GO:0007165| signal transduction CD86;PDGFRB;RET 24893:[DB01281 DB11590] DB01281|Abatacept CD80;CD86 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes common pathways GO:0007165| signal transduction ITPR1;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;GPX1;CD86 24894:[DB01281 DB08607] DB01281|Abatacept CD80;CD86 DB08607|(5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE CYP2C8;FABP4 common genes common pathways 24895:[DB01281 DB06481] DB01281|Abatacept CD80;CD86 DB06481|Manitimus DHODH common genes common pathways 24896:[DB01281 DB07015] DB01281|Abatacept CD80;CD86 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;DPP4 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;DPP4;CD86 24897:[DB01281 DB00167] DB01281|Abatacept CD80;CD86 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways 24898:[DB01281 DB02459] DB01281|Abatacept CD80;CD86 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways GO:0002376| immune system process CD86;CFB 24899:[DB01281 DB03845] DB01281|Abatacept CD80;CD86 DB03845|P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate DTYMK common genes common pathways 24900:[DB01281 DB00241] DB01281|Abatacept CD80;CD86 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GRIA2;CHRNA4;CHRNA7;GABRB3;GABRB1;GABRQ;GABRE;GABRA6;CD86;GABRA5;GABRP;GABRD GO:0008284| positive regulation of cell proliferation CHRNA7;CD86 24901:[DB01281 DB02638] DB01281|Abatacept CD80;CD86 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways GO:0007165| signal transduction AVPR1B;CD86;AVPR2;AVPR1A GO:0008284| positive regulation of cell proliferation AVPR2;CD86;AVPR1A 24902:[DB01281 DB05159] DB01281|Abatacept CD80;CD86 DB05159|CCX915 CCR2 common genes common pathways GO:0007165| signal transduction CCR2;CD86 GO:0016032| viral reproduction CD86;CD80;CCR2 GO:0006955| immune response CD86;CCR2 24903:[DB01281 DB06069] DB01281|Abatacept CD80;CD86 DB06069|XMT-1001 TOP1 common genes common pathways GO:0016032| viral reproduction TOP1;CD80;CD86 24904:[DB01281 DB02074] DB01281|Abatacept CD80;CD86 DB02074|Butenoic Acid FABP1 common genes common pathways 24905:[DB01281 DB14033] DB01281|Abatacept CD80;CD86 DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways 24906:[DB01281 DB05712] DB01281|Abatacept CD80;CD86 DB05712|AZD-9684 CPB2 common genes common pathways 24907:[DB01281 DB00467] DB01281|Abatacept CD80;CD86 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways 24908:[DB01281 DB08837] DB01281|Abatacept CD80;CD86 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0007165| signal transduction CHRNA9;CD86 24909:[DB01281 DB03336] DB01281|Abatacept CD80;CD86 DB03336|BIA COMT common genes common pathways 24910:[DB01281 DB12693] DB01281|Abatacept CD80;CD86 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0046718| entry of virus into host cell HTR2A;CD80;CD86 GO:0007165| signal transduction HTR2A;CD86 GO:0008284| positive regulation of cell proliferation CD86;HTR2A 24911:[DB01281 DB06817] DB01281|Abatacept CD80;CD86 DB06817|Raltegravir pol;UGT1A1 common genes common pathways 24912:[DB01281 DB04715] DB01281|Abatacept CD80;CD86 DB04715|IMIDAZOPYRIDAZIN 1 PIM1 common genes common pathways 24913:[DB01281 DB06892] DB01281|Abatacept CD80;CD86 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways GO:0007165| signal transduction MAP2K1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;MAP2K1;CD80 24914:[DB01281 DB05553] DB01281|Abatacept CD80;CD86 DB05553|Regrelor P2RY12 common genes common pathways GO:0007165| signal transduction P2RY12;CD86 24915:[DB01281 DB14031] DB01281|Abatacept CD80;CD86 DB14031|Tretamine BCHE common genes common pathways 24916:[DB01281 DB00013] DB01281|Abatacept CD80;CD86 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0007165| signal transduction PLAUR;PLAU;CD86 24917:[DB01281 DB05045] DB01281|Abatacept CD80;CD86 DB05045|Obinepitide NPY4R;NPY2R common genes common pathways GO:0007165| signal transduction CD86;NPY4R;NPY2R 24918:[DB01281 DB08672] DB01281|Abatacept CD80;CD86 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD80;CD86;DPP4 24919:[DB01281 DB01863] DB01281|Abatacept CD80;CD86 DB01863|Inositol 1,3,4,5-Tetrakisphosphate AKT1;PLEKHA4;BTK;DAPP1;ITPKA;CYTH2;CYTH3;PDPK1 common genes common pathways GO:0002376| immune system process CD86;BTK GO:0031295| T cell costimulation AKT1;CD80;CD86;PDPK1 GO:0008284| positive regulation of cell proliferation AKT1;CD86 GO:0002250| adaptive immune response BTK;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;AKT1;CD80 GO:0007165| signal transduction AKT1;DAPP1;CD86;ITPKA GO:0035556| intracellular signal transduction BTK;CD80;AKT1;PDPK1 24920:[DB01281 DB07176] DB01281|Abatacept CD80;CD86 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways 24921:[DB01281 DB00206] DB01281|Abatacept CD80;CD86 DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BIRC5 24922:[DB01281 DB04648] DB01281|Abatacept CD80;CD86 DB04648|S-propylamine-L-cysteine ARG1 common genes common pathways GO:0002250| adaptive immune response CD86;ARG1 GO:0002376| immune system process CD86;ARG1 24923:[DB01281 DB03306] DB01281|Abatacept CD80;CD86 DB03306|RU78300 SRC common genes common pathways GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0002376| immune system process CD86;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0007165| signal transduction CD86;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD86;SRC;CD80 GO:0035556| intracellular signal transduction CD80;SRC 24924:[DB01281 DB00137] DB01281|Abatacept CD80;CD86 DB00137|Lutein ALB common genes common pathways 24925:[DB01281 DB08954] DB01281|Abatacept CD80;CD86 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways 24926:[DB01281 DB01345] DB01281|Abatacept CD80;CD86 DB01345|Potassium cation ATP1A1 common genes common pathways 24927:[DB01281 DB11338] DB01281|Abatacept CD80;CD86 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0006955| immune response CXCL10;CD86 GO:0016032| viral reproduction VCAM1;CD80;CD86 GO:0007165| signal transduction CD86;CXCL10 GO:0008284| positive regulation of cell proliferation CD86;CXCL10 GO:0045893| positive regulation of transcription, DNA-dependent CD86;COL1A1;CD80 24928:[DB01281 DB00505] DB01281|Abatacept CD80;CD86 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CD86;CHRM3;CHRM1;CHRM2 24929:[DB01281 DB09499] DB01281|Abatacept CD80;CD86 DB09499|Thiosulfuric acid TST common genes common pathways 24930:[DB01281 DB00166] DB01281|Abatacept CD80;CD86 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways 24931:[DB01281 DB04149] DB01281|Abatacept CD80;CD86 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways GO:0007165| signal transduction PDE4D;CD86;PDE4B 24932:[DB01281 DB08370] DB01281|Abatacept CD80;CD86 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways 24933:[DB01281 DB00837] DB01281|Abatacept CD80;CD86 DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0007165| signal transduction CD86;GABBR1 24934:[DB01281 DB06785] DB01281|Abatacept CD80;CD86 DB06785|Ganirelix GNRHR common genes common pathways GO:0007165| signal transduction CD86;GNRHR 24935:[DB01281 DB11235] DB01281|Abatacept CD80;CD86 DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;CHRM5;HRH1;CD86;CHRM4;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 24936:[DB01281 DB13620] DB01281|Abatacept CD80;CD86 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways 24937:[DB01281 DB05137] DB01281|Abatacept CD80;CD86 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;CD86 GO:0007165| signal transduction CHRNA7;CHRNA10;CD86;CHRNA9 24938:[DB01281 DB14071] DB01281|Abatacept CD80;CD86 DB14071|Desmethylsertraline ABCB1 common genes common pathways 24939:[DB01281 DB03496] DB01281|Abatacept CD80;CD86 DB03496|Alvocidib CDK2;CDK5;CDK9;CDK1;CDK6;EGFR;CDK4;CDK8;CDK7;PYGM;PYGB;PYGL;UGT1A1;ABCG2 common genes common pathways GO:0035556| intracellular signal transduction CD80;EGFR GO:0046718| entry of virus into host cell EGFR;CD86;CDK1;CD80 GO:0007165| signal transduction CDK4;CDK6;EGFR;CD86 GO:0008284| positive regulation of cell proliferation CDK4;CDK2;CD86;EGFR GO:0045893| positive regulation of transcription, DNA-dependent CD86;EGFR;CDK2;CDK7;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;EGFR;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;EGFR 24940:[DB01281 DB04459] DB01281|Abatacept CD80;CD86 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways GO:0002376| immune system process CD86;CFD 24941:[DB01281 DB07101] DB01281|Abatacept CD80;CD86 DB07101|PD-0325901 MAP2K1 common genes common pathways GO:0007165| signal transduction CD86;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;CD80;CD86 24942:[DB01281 DB04754] DB01281|Abatacept CD80;CD86 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0006955| immune response CD86;PNP 24943:[DB01281 DB03695] DB01281|Abatacept CD80;CD86 DB03695|Piritrexim DHFR common genes common pathways 24944:[DB01281 DB01979] DB01281|Abatacept CD80;CD86 DB01979|Methyl alpha-D-mannoside MBL2 common genes common pathways GO:0002376| immune system process CD86;MBL2 24945:[DB01281 DB02845] DB01281|Abatacept CD80;CD86 DB02845|Methylphosphinic Acid BCHE;ACHE;BCHE common genes common pathways 24946:[DB01281 DB00915] DB01281|Abatacept CD80;CD86 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 GO:0007165| signal transduction CHRNA4;CHRNA7;DRD2;CHRNA3;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 24947:[DB01281 DB02877] DB01281|Abatacept CD80;CD86 DB02877|Arotinoid acid RARB common genes common pathways GO:0007165| signal transduction CD86;RARB GO:0008284| positive regulation of cell proliferation CD86;RARB 24948:[DB01281 DB08454] DB01281|Abatacept CD80;CD86 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways GO:0035556| intracellular signal transduction CAMK1D;CD80 24949:[DB01281 DB07469] DB01281|Abatacept CD80;CD86 DB07469|(3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 24950:[DB01281 DB06706] DB01281|Abatacept CD80;CD86 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0035556| intracellular signal transduction ADRA1A;CD80 GO:0007165| signal transduction ADRA1A;CD86 24951:[DB01281 DB02373] DB01281|Abatacept CD80;CD86 DB02373|Adenosine Monotungstate FHIT common genes common pathways 24952:[DB01281 DB11792] DB01281|Abatacept CD80;CD86 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 24953:[DB01281 DB03856] DB01281|Abatacept CD80;CD86 DB03856|L-Eflornithine ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ODC1 24954:[DB01281 DB07339] DB01281|Abatacept CD80;CD86 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways 24955:[DB01281 DB04956] DB01281|Abatacept CD80;CD86 DB04956|Afelimomab TNF common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;TNF;CD80 GO:0006955| immune response CD86;TNF 24956:[DB01281 DB06471] DB01281|Abatacept CD80;CD86 DB06471|Naxifylline ADORA1 common genes common pathways GO:0007165| signal transduction CD86;ADORA1 24957:[DB01281 DB00423] DB01281|Abatacept CD80;CD86 DB00423|Methocarbamol CA1 common genes common pathways 24958:[DB01281 DB02776] DB01281|Abatacept CD80;CD86 DB02776|1-Hexadecanosulfonic Acid FABP4 common genes common pathways 24959:[DB01281 DB01933] DB01281|Abatacept CD80;CD86 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways GO:0035556| intracellular signal transduction PDPK1;CD80 GO:0031295| T cell costimulation CD80;PDPK1;CD86 24960:[DB01281 DB08365] DB01281|Abatacept CD80;CD86 DB08365|8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide WEE1 common genes common pathways 24961:[DB01281 DB03606] DB01281|Abatacept CD80;CD86 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways GO:0007165| signal transduction CD86;PDE4B;PDE4D 24962:[DB01281 DB11477] DB01281|Abatacept CD80;CD86 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0007165| signal transduction ADRA2A;CD86;ADRA2C;ADRA2B GO:0008284| positive regulation of cell proliferation ADRA2A;CD86 24963:[DB01281 DB00244] DB01281|Abatacept CD80;CD86 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CHUK;CD80;IKBKB;CD86;PPARG GO:0008284| positive regulation of cell proliferation CD86;PTGS2 GO:0007165| signal transduction CD86;PPARG GO:0006955| immune response CHUK;CD86 24964:[DB01281 DB03977] DB01281|Abatacept CD80;CD86 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways 24965:[DB01281 DB00070] DB01281|Abatacept CD80;CD86 DB00070|Hyaluronidase TGFB1;ALB common genes common pathways GO:0008284| positive regulation of cell proliferation TGFB1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;TGFB1;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;TGFB1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;TGFB1 24966:[DB01281 DB00274] DB01281|Abatacept CD80;CD86 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways 24967:[DB01281 DB01352] DB01281|Abatacept CD80;CD86 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 GO:0007165| signal transduction CHRNA4;GRIA2;CHRNA7;GABRA6;CD86;GABRA5 24968:[DB01281 DB02255] DB01281|Abatacept CD80;CD86 DB02255|GM6001 ADAM28;ACAN common genes common pathways 24969:[DB01281 DB06468] DB01281|Abatacept CD80;CD86 DB06468|Cariporide SLC9A1;MPO common genes common pathways 24970:[DB01281 DB07638] DB01281|Abatacept CD80;CD86 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways GO:0007165| signal transduction CD86;ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;CD80;ESR1 24971:[DB01281 DB06833] DB01281|Abatacept CD80;CD86 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESRRA;CD80 24972:[DB01281 DB13932] DB01281|Abatacept CD80;CD86 DB13932|Voretigene Neparvovec RPE65 common genes common pathways 24973:[DB01281 DB07967] DB01281|Abatacept CD80;CD86 DB07967|9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE CTSK common genes common pathways 24974:[DB01281 DB06358] DB01281|Abatacept CD80;CD86 DB06358|Iclaprim DHFR common genes common pathways 24975:[DB01281 DB02306] DB01281|Abatacept CD80;CD86 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 24976:[DB01281 DB09276] DB01281|Abatacept CD80;CD86 DB09276|Sodium aurothiomalate UGT1A1 common genes common pathways 24977:[DB01281 DB00689] DB01281|Abatacept CD80;CD86 DB00689|Cephaloglycin SLC22A5 common genes common pathways 24978:[DB01281 DB08089] DB01281|Abatacept CD80;CD86 DB08089|LGD-2226 AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 24979:[DB01281 DB01044] DB01281|Abatacept CD80;CD86 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways 24980:[DB01281 DB04012] DB01281|Abatacept CD80;CD86 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways 24981:[DB01281 DB02557] DB01281|Abatacept CD80;CD86 DB02557|Phosphoramidon MME;KEL common genes common pathways 24982:[DB01281 DB04281] DB01281|Abatacept CD80;CD86 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways 24983:[DB01281 DB05171] DB01281|Abatacept CD80;CD86 DB05171|E-2012 APH1A;PSENEN common genes common pathways 24984:[DB01281 DB03332] DB01281|Abatacept CD80;CD86 DB03332|5,6-Cyclic-Tetrahydropteridine NOS3 common genes common pathways 24985:[DB01281 DB04894] DB01281|Abatacept CD80;CD86 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0007165| signal transduction SSTR2;CD86;TACR1;SSTR5 24986:[DB01281 DB00772] DB01281|Abatacept CD80;CD86 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways 24987:[DB01281 DB03760] DB01281|Abatacept CD80;CD86 DB03760|Dihydrolipoic Acid GCSH;DLAT;PDK3 common genes common pathways 24988:[DB01281 DB07135] DB01281|Abatacept CD80;CD86 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;DPP4 GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 24989:[DB01281 DB07525] DB01281|Abatacept CD80;CD86 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation FGFR1;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;FGFR1;CD86 GO:0008284| positive regulation of cell proliferation FGFR1;CD86 24990:[DB01281 DB06993] DB01281|Abatacept CD80;CD86 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;CD86;DPP4 24991:[DB01281 DB05667] DB01281|Abatacept CD80;CD86 DB05667|Levoketoconazole CYP11B1;CYP51A1 common genes common pathways GO:0006955| immune response CYP11B1;CD86 24992:[DB01281 DB06184] DB01281|Abatacept CD80;CD86 DB06184|AEG35156 XIAP common genes common pathways 24993:[DB01281 DB02919] DB01281|Abatacept CD80;CD86 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways 24994:[DB01281 DB07141] DB01281|Abatacept CD80;CD86 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 24995:[DB01281 DB00421] DB01281|Abatacept CD80;CD86 DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0007165| signal transduction NR3C1;AR;NR1I2;PGR;CACNA1I;CD86;NR3C2 GO:0006955| immune response CD86;CYP11B1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;NR1I2;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR 24996:[DB01281 DB05078] DB01281|Abatacept CD80;CD86 DB05078|AER001 IL4R;IL13RA2 common genes common pathways GO:0002376| immune system process CD86;IL4R GO:0045630| positive regulation of T-helper 2 cell differentiation CD86;IL4R GO:0007165| signal transduction CD86;IL13RA2;IL4R GO:0006955| immune response IL4R;CD86 24997:[DB01281 DB00572] DB01281|Abatacept CD80;CD86 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CHRM2;CHRM1;CHRM5;CHRNA4;CHRM3;CHRNB2;CD86;CHRM4 24998:[DB01281 DB05332] DB01281|Abatacept CD80;CD86 DB05332|Romiplostim MPL common genes common pathways 24999:[DB01281 DB05339] DB01281|Abatacept CD80;CD86 DB05339|MN-305 HTR1A common genes common pathways GO:0007165| signal transduction HTR1A;CD86 GO:0008284| positive regulation of cell proliferation HTR1A;CD86 25000:[DB01281 DB00598] DB01281|Abatacept CD80;CD86 DB00598|Labetalol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP2C19 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;CD86 GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A GO:0007165| signal transduction ADRB2;ADRA1B;ADRA1D;CD86;ADRB1;ADRA1A 25001:[DB01281 DB07036] DB01281|Abatacept CD80;CD86 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways GO:0007165| signal transduction CD86;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR2;CD86 25002:[DB01281 DB00415] DB01281|Abatacept CD80;CD86 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0035556| intracellular signal transduction CD80;TEK GO:0007165| signal transduction CD86;TEK GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TEK;CD80 25003:[DB01281 DB00110] DB01281|Abatacept CD80;CD86 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction FCGR2B;FCGR1A;CD86;FCGR2C GO:0006955| immune response C1R;FCGR3B;FCGR2B;FCGR1A;CD86;FCGR3A;FCGR2C;C1QC GO:0016032| viral reproduction FCGR2B;CD86;CD80 GO:0002376| immune system process C1QB;C1R;FCGR2A;FCGR1A;CD86;C1QC;C1QA 25004:[DB01281 DB05139] DB01281|Abatacept CD80;CD86 DB05139|CR002 PDGFD common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PDGFD 25005:[DB01281 DB11275] DB01281|Abatacept CD80;CD86 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0008284| positive regulation of cell proliferation DRD3;CD86 GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD5;DRD1;DRD4;DRD2;CD86;DRD3 25006:[DB01281 DB00650] DB01281|Abatacept CD80;CD86 DB00650|Leucovorin SLC22A8 common genes common pathways 25007:[DB01281 DB07028] DB01281|Abatacept CD80;CD86 DB07028|(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID AKR1B1 common genes common pathways 25008:[DB01281 DB04738] DB01281|Abatacept CD80;CD86 DB04738|Motuporin PPP1CC common genes common pathways 25009:[DB01281 DB01247] DB01281|Abatacept CD80;CD86 DB01247|Isocarboxazid MAOA;MAOB common genes common pathways 25010:[DB01281 DB08449] DB01281|Abatacept CD80;CD86 DB08449|2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid AKR1B1 common genes common pathways 25011:[DB01281 DB07542] DB01281|Abatacept CD80;CD86 DB07542|5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOBUTYL-HEXANOIC ACID CTSD common genes common pathways 25012:[DB01281 DB05001] DB01281|Abatacept CD80;CD86 DB05001|PSN9301 DPP4 common genes common pathways GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD80;DPP4;CD86 25013:[DB01281 DB11973] DB01281|Abatacept CD80;CD86 DB11973|Tesevatinib EGF;EPHB4;ERBB2 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;EGF GO:0007165| signal transduction CD86;EGF;ERBB2 GO:0051897| positive regulation of protein kinase B signaling cascade EGF;CD80;ERBB2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;EGF GO:0008284| positive regulation of cell proliferation EGF;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;ERBB2;CD80;EGF 25014:[DB01281 DB06857] DB01281|Abatacept CD80;CD86 DB06857|N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 25015:[DB01281 DB13933] DB01281|Abatacept CD80;CD86 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;F7;CD86 25016:[DB01281 DB04796] DB01281|Abatacept CD80;CD86 DB04796|Inecalcitol VDR common genes common pathways GO:0007165| signal transduction VDR;CD86 25017:[DB01281 DB13948] DB01281|Abatacept CD80;CD86 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CD86 GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0007165| signal transduction HTR2A;CD86 GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A 25018:[DB01281 DB08574] DB01281|Abatacept CD80;CD86 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 25019:[DB01281 DB07768] DB01281|Abatacept CD80;CD86 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AKR1C2 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;AKR1C2;CD80 25020:[DB01281 DB01053] DB01281|Abatacept CD80;CD86 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways 25021:[DB01281 DB06830] DB01281|Abatacept CD80;CD86 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 25022:[DB01281 DB03247] DB01281|Abatacept CD80;CD86 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0035556| intracellular signal transduction SGK1;CD80;RPS6KA4 GO:0045893| positive regulation of transcription, DNA-dependent CD80;NOS1;CD86 25023:[DB01281 DB03907] DB01281|Abatacept CD80;CD86 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways 25024:[DB01281 DB01085] DB01281|Abatacept CD80;CD86 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;CHRM3;CHRM4;CD86 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 25025:[DB01281 DB06354] DB01281|Abatacept CD80;CD86 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways GO:0007165| signal transduction GABBR1;CD86 25026:[DB01281 DB12773] DB01281|Abatacept CD80;CD86 DB12773|Sifalimumab IFNA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;IFNA2;CD86 25027:[DB01281 DB04893] DB01281|Abatacept CD80;CD86 DB04893|AZD3409 FNTB;FNTA common genes common pathways 25028:[DB01281 DB07068] DB01281|Abatacept CD80;CD86 DB07068|(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID PTPRB common genes common pathways 25029:[DB01281 DB04521] DB01281|Abatacept CD80;CD86 DB04521|GSHNA GSTA3 common genes common pathways 25030:[DB01281 DB04756] DB01281|Abatacept CD80;CD86 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways 25031:[DB01281 DB02018] DB01281|Abatacept CD80;CD86 DB02018|Amido Phenyl Pyruvic Acid TPSB2 common genes common pathways 25032:[DB01281 DB11731] DB01281|Abatacept CD80;CD86 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways GO:0007165| signal transduction CD86;EGFR GO:0046718| entry of virus into host cell EGFR;CD86;CD80 GO:0035556| intracellular signal transduction CD80;EGFR GO:0046854| phosphatidylinositol phosphorylation EGFR;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;EGFR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;EGFR GO:0008284| positive regulation of cell proliferation EGFR;CD86 25033:[DB01281 DB04753] DB01281|Abatacept CD80;CD86 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0006955| immune response CD86;PNP 25034:[DB01281 DB02264] DB01281|Abatacept CD80;CD86 DB02264|O2-Sulfo-Glucuronic Acid FGF1;HGF;HS3ST3A1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HGF GO:0007165| signal transduction FGF1;CD86 GO:0008284| positive regulation of cell proliferation FGF1;HGF;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;HGF;FGF1;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;FGF1;CD86;HGF 25035:[DB01281 DB05883] DB01281|Abatacept CD80;CD86 DB05883|ABX-PTH PTH common genes common pathways GO:0009967| positive regulation of signal transduction CD80;PTH 25036:[DB01281 DB08841] DB01281|Abatacept CD80;CD86 DB08841|Tyramine SLC22A3 common genes common pathways 25037:[DB01281 DB08814] DB01281|Abatacept CD80;CD86 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;NFKB1;CD80 GO:0007165| signal transduction NFKB1;PDE10A;CD86 25038:[DB01281 DB07443] DB01281|Abatacept CD80;CD86 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways 25039:[DB01281 DB07032] DB01281|Abatacept CD80;CD86 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways GO:0007165| signal transduction CD86;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;CD80 25040:[DB01281 DB09272] DB01281|Abatacept CD80;CD86 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;CD86;OPRK1 GO:0006955| immune response OPRK1;CD86;OPRD1 25041:[DB01281 DB07625] DB01281|Abatacept CD80;CD86 DB07625|4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 25042:[DB01281 DB00024] DB01281|Abatacept CD80;CD86 DB00024|Thyrotropin alfa TSHR common genes common pathways GO:0008284| positive regulation of cell proliferation TSHR;CD86 GO:0007165| signal transduction TSHR;CD86 25043:[DB01281 DB05814] DB01281|Abatacept CD80;CD86 DB05814|GPI-1485 FKBP1A;CYP3A4 common genes common pathways 25044:[DB01281 DB00657] DB01281|Abatacept CD80;CD86 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0007165| signal transduction CD86;CHRNB2;CHRNA7;CHRNA2;CHRNA4 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 25045:[DB01281 DB08844] DB01281|Abatacept CD80;CD86 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways 25046:[DB01281 DB01375] DB01281|Abatacept CD80;CD86 DB01375|Aluminium monostearate TNNC1;VDAC1;VDAC2;VDAC3 common genes common pathways GO:0016032| viral reproduction CD80;VDAC1;CD86 25047:[DB01281 DB07945] DB01281|Abatacept CD80;CD86 DB07945|5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid FABP4 common genes common pathways 25048:[DB01281 DB09110] DB01281|Abatacept CD80;CD86 DB09110|Coenzyme M GSR common genes common pathways 25049:[DB01281 DB00810] DB01281|Abatacept CD80;CD86 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0007165| signal transduction CHRNA2;CHRM1;CD86 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 25050:[DB01281 DB08382] DB01281|Abatacept CD80;CD86 DB08382|Gosogliptin DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 25051:[DB01281 DB09460] DB01281|Abatacept CD80;CD86 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways 25052:[DB01281 DB02613] DB01281|Abatacept CD80;CD86 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways 25053:[DB01281 DB13873] DB01281|Abatacept CD80;CD86 DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARD;CD80;PPARA;CD86;NR1I2;PPARG GO:0008284| positive regulation of cell proliferation PPARD;CD86 GO:0007165| signal transduction CD86;NR1I2;PPARG 25054:[DB01281 DB05361] DB01281|Abatacept CD80;CD86 DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;F2R;CD80 GO:0008284| positive regulation of cell proliferation F2R;CD86 GO:0007165| signal transduction F2R;CD86 25055:[DB01281 DB08784] DB01281|Abatacept CD80;CD86 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 25056:[DB01281 DB02285] DB01281|Abatacept CD80;CD86 DB02285|Protoporphyrin FTL common genes common pathways 25057:[DB01281 DB00038] DB01281|Abatacept CD80;CD86 DB00038|Oprelvekin IL11RA common genes common pathways GO:0007165| signal transduction CD86;IL11RA 25058:[DB01281 DB07249] DB01281|Abatacept CD80;CD86 DB07249|N-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine EPHB4 common genes common pathways 25059:[DB01281 DB00512] DB01281|Abatacept CD80;CD86 DB00512|Vancomycin ALB;ORM1;ORM2 common genes common pathways 25060:[DB01281 DB06231] DB01281|Abatacept CD80;CD86 DB06231|Caldaret SLC8A1 common genes common pathways 25061:[DB01281 DB00733] DB01281|Abatacept CD80;CD86 DB00733|Pralidoxime ACHE;BCHE common genes common pathways 25062:[DB01281 DB00160] DB01281|Abatacept CD80;CD86 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways 25063:[DB01281 DB00596] DB01281|Abatacept CD80;CD86 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 25064:[DB01281 DB07008] DB01281|Abatacept CD80;CD86 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways 25065:[DB01281 DB00094] DB01281|Abatacept CD80;CD86 DB00094|Urofollitropin FSHR common genes common pathways GO:0007165| signal transduction FSHR;CD86 25066:[DB01281 DB00189] DB01281|Abatacept CD80;CD86 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRD;GABRP;GABRA5;CD86;GABRA6;GABRE;GABRQ;GABRB1;GABRB3 25067:[DB01281 DB09395] DB01281|Abatacept CD80;CD86 DB09395|Sodium acetate ACSS2 common genes common pathways 25068:[DB01281 DB11639] DB01281|Abatacept CD80;CD86 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways GO:0006955| immune response BMPR1A;CD86 GO:0045893| positive regulation of transcription, DNA-dependent BMPR1A;CD80;CD86 25069:[DB01281 DB11075] DB01281|Abatacept CD80;CD86 DB11075|Hypromellose EPCAM common genes common pathways GO:0008284| positive regulation of cell proliferation EPCAM;CD86 25070:[DB01281 DB01366] DB01281|Abatacept CD80;CD86 DB01366|Procaterol ADRB2 common genes common pathways GO:0007165| signal transduction CD86;ADRB2 25071:[DB01281 DB00385] DB01281|Abatacept CD80;CD86 DB00385|Valrubicin TOP2A common genes common pathways 25072:[DB01281 DB14596] DB01281|Abatacept CD80;CD86 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 25073:[DB01281 DB01440] DB01281|Abatacept CD80;CD86 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;SLC52A2 GO:0007165| signal transduction GABRB1;CD86 25074:[DB01281 DB00920] DB01281|Abatacept CD80;CD86 DB00920|Ketotifen HRH1;PGD common genes common pathways GO:0007165| signal transduction CD86;HRH1 25075:[DB01281 DB04207] DB01281|Abatacept CD80;CD86 DB04207|N-(5-Amino-5-Carboxypentyl)Glutamic Acid AASS common genes common pathways 25076:[DB01281 DB08874] DB01281|Abatacept CD80;CD86 DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways 25077:[DB01281 DB13036] DB01281|Abatacept CD80;CD86 DB13036|Ramatroban PTGDR2 common genes common pathways GO:0006955| immune response CD86;PTGDR2 GO:0007165| signal transduction PTGDR2;CD86 25078:[DB01281 DB14530] DB01281|Abatacept CD80;CD86 DB14530|Chromous sulfate CYB5A;TF common genes common pathways 25079:[DB01281 DB01144] DB01281|Abatacept CD80;CD86 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 25080:[DB01281 DB00558] DB01281|Abatacept CD80;CD86 DB00558|Zanamivir NEU2 common genes common pathways 25081:[DB01281 DB08168] DB01281|Abatacept CD80;CD86 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways 25082:[DB01281 DB13997] DB01281|Abatacept CD80;CD86 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways 25083:[DB01281 DB03958] DB01281|Abatacept CD80;CD86 DB03958|7-methyl-guanosine-5'-triphosphate-5'-guanosine DCPS common genes common pathways 25084:[DB01281 DB01083] DB01281|Abatacept CD80;CD86 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways 25085:[DB01281 DB08044] DB01281|Abatacept CD80;CD86 DB08044|ABT-341 DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0031295| T cell costimulation CD80;CD86;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CD86 25086:[DB01281 DB14582] DB01281|Abatacept CD80;CD86 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways 25087:[DB01281 DB00691] DB01281|Abatacept CD80;CD86 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0016032| viral reproduction ACE2;CD80;CD86 GO:0046718| entry of virus into host cell CD86;ACE2;CD80 25088:[DB01281 DB02322] DB01281|Abatacept CD80;CD86 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways GO:0006955| immune response CCL5;CD86 25089:[DB01281 DB05442] DB01281|Abatacept CD80;CD86 DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0007165| signal transduction CD86;IL1B GO:0006955| immune response CD86;IL1B GO:0045086| positive regulation of interleukin-2 biosynthetic process CD80;IL1B;CD86 GO:0008284| positive regulation of cell proliferation IL1B;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;IL1B 25090:[DB01281 DB03864] DB01281|Abatacept CD80;CD86 DB03864|Monothioglycerol PREP common genes common pathways 25091:[DB01281 DB09060] DB01281|Abatacept CD80;CD86 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways 25092:[DB01281 DB04733] DB01281|Abatacept CD80;CD86 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways 25093:[DB01281 DB00434] DB01281|Abatacept CD80;CD86 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1;HTR2A GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0046718| entry of virus into host cell CD86;CD80;HTR2A GO:0007165| signal transduction HRH1;HTR2A;CHRM2;CHRM1;CHRM3;HTR7;CD86;HTR2C 25094:[DB01281 DB08594] DB01281|Abatacept CD80;CD86 DB08594|TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE CTSK common genes common pathways 25095:[DB01281 DB04114] DB01281|Abatacept CD80;CD86 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways 25096:[DB01281 DB01599] DB01281|Abatacept CD80;CD86 DB01599|Probucol ABCA1;CES1 common genes common pathways 25097:[DB01281 DB12465] DB01281|Abatacept CD80;CD86 DB12465|Ketanserin HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HTR2A GO:0016032| viral reproduction CD86;HTR2A;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0007165| signal transduction CD86;HTR2A GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 25098:[DB01281 DB04559] DB01281|Abatacept CD80;CD86 DB04559|N-(Chlorophenyl)-N'-Hydroxyguanidine NOS3 common genes common pathways 25099:[DB01281 DB09258] DB01281|Abatacept CD80;CD86 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 25100:[DB01281 DB02485] DB01281|Abatacept CD80;CD86 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 25101:[DB01281 DB09046] DB01281|Abatacept CD80;CD86 DB09046|Metreleptin LEPR common genes common pathways 25102:[DB01281 DB08153] DB01281|Abatacept CD80;CD86 DB08153|(5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE HSP90AB1 common genes common pathways 25103:[DB01281 DB04250] DB01281|Abatacept CD80;CD86 DB04250|Butyrylthiocholine BCHE;BCHE common genes common pathways 25104:[DB01281 DB05936] DB01281|Abatacept CD80;CD86 DB05936|CVT-6883 ADORA2B common genes common pathways GO:0007165| signal transduction CD86;ADORA2B 25105:[DB01281 DB08426] DB01281|Abatacept CD80;CD86 DB08426|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 25106:[DB01281 DB03305] DB01281|Abatacept CD80;CD86 DB03305|N5-Iminoethyl-L-Ornithine NOS3 common genes common pathways 25107:[DB01281 DB01736] DB01281|Abatacept CD80;CD86 DB01736|[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium SLC25A4 common genes common pathways GO:0016032| viral reproduction CD80;CD86;SLC25A4 25108:[DB01281 DB03604] DB01281|Abatacept CD80;CD86 DB03604|Tiratricol THRB common genes common pathways 25109:[DB01281 DB11755] DB01281|Abatacept CD80;CD86 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0006955| immune response CD86;CNR2 GO:0007165| signal transduction CD86;CNR2;HTR1A;GPR55;CNR1 GO:0008284| positive regulation of cell proliferation HTR1A;CD86 25110:[DB01281 DB04672] DB01281|Abatacept CD80;CD86 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways 25111:[DB01281 DB06140] DB01281|Abatacept CD80;CD86 DB06140|SUVN-502 HTR6 common genes common pathways GO:0007165| signal transduction HTR6;CD86 25112:[DB01281 DB00702] DB01281|Abatacept CD80;CD86 DB00702|Icodextrin AMY2A common genes common pathways 25113:[DB01281 DB01425] DB01281|Abatacept CD80;CD86 DB01425|Alizapride DRD2 common genes common pathways GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction DRD2;CD86 25114:[DB01281 DB01057] DB01281|Abatacept CD80;CD86 DB01057|Echothiophate BCHE;ALB common genes common pathways 25115:[DB01281 DB01998] DB01281|Abatacept CD80;CD86 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways 25116:[DB01281 DB13168] DB01281|Abatacept CD80;CD86 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 25117:[DB01281 DB03066] DB01281|Abatacept CD80;CD86 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 25118:[DB01281 DB11892] DB01281|Abatacept CD80;CD86 DB11892|Prulifloxacin CYP1A2 common genes common pathways 25119:[DB01281 DB06756] DB01281|Abatacept CD80;CD86 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0008284| positive regulation of cell proliferation BCL2;CD86 25120:[DB01281 DB07389] DB01281|Abatacept CD80;CD86 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways 25121:[DB01281 DB03073] DB01281|Abatacept CD80;CD86 DB03073|3-Methoxybenzamide PARP1 common genes common pathways 25122:[DB01281 DB03009] DB01281|Abatacept CD80;CD86 DB03009|2-[(2-Oxo-2-Piperidin-1-Ylethyl)Thio]-6-(Trifluoromethyl)Pyrimidin-4(1h)-One FABP4 common genes common pathways 25123:[DB01281 DB09332] DB01281|Abatacept CD80;CD86 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;F2 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86;F7 25124:[DB01281 DB01170] DB01281|Abatacept CD80;CD86 DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways 25125:[DB01281 DB01750] DB01281|Abatacept CD80;CD86 DB01750|1-naphthaleneacetic acid SKP1 common genes common pathways 25126:[DB01281 DB02596] DB01281|Abatacept CD80;CD86 DB02596|Alpha,Beta-Methyleneadenosine-5'-Triphosphate folK;panC;nadE;NMNAT3;carA common genes common pathways 25127:[DB01281 DB05327] DB01281|Abatacept CD80;CD86 DB05327|Ranirestat AKR1B1 common genes common pathways 25128:[DB01281 DB00029] DB01281|Abatacept CD80;CD86 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007165| signal transduction FGA;PLAUR;CD86 GO:0002376| immune system process FGA;CD86 GO:0002250| adaptive immune response FGA;CD86 25129:[DB01281 DB08051] DB01281|Abatacept CD80;CD86 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 25130:[DB01281 DB08127] DB01281|Abatacept CD80;CD86 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways GO:0007165| signal transduction CRABP2;CD86 25131:[DB01281 DB03023] DB01281|Abatacept CD80;CD86 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0035556| intracellular signal transduction LYN;SRC;CD80 GO:0016032| viral reproduction LYN;CD86;LCK;CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation LYN;CD80;SRC GO:0007165| signal transduction LYN;CD86;SRC GO:0008284| positive regulation of cell proliferation CD86;LYN GO:0002250| adaptive immune response CD86;LYN GO:0051897| positive regulation of protein kinase B signaling cascade CD86;LCK;CD80;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0002376| immune system process LYN;CD86;SRC GO:0031295| T cell costimulation LYN;CD86;LCK;CD80;SRC GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;LCK 25132:[DB01281 DB11779] DB01281|Abatacept CD80;CD86 DB11779|Danoprevir CYP3A4 common genes common pathways 25133:[DB01281 DB04930] DB01281|Abatacept CD80;CD86 DB04930|Permethrin SCN1A;ESR1;NR1I2;CYP2B6;CYP3A4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CD86;CD80;ESR1 GO:0007165| signal transduction CD86;NR1I2;ESR1 25134:[DB01281 DB07274] DB01281|Abatacept CD80;CD86 DB07274|N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide KDR common genes common pathways GO:0016032| viral reproduction CD80;KDR;CD86 GO:0008284| positive regulation of cell proliferation CD86;KDR 25135:[DB01281 DB07979] DB01281|Abatacept CD80;CD86 DB07979|(2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID DAO common genes common pathways 25136:[DB01281 DB03344] DB01281|Abatacept CD80;CD86 DB03344|Inositol-(1,3,4,5,6)-Pentakisphosphate CYTH3 common genes common pathways 25137:[DB01281 DB05130] DB01281|Abatacept CD80;CD86 DB05130|INCB3284 CCR2 common genes common pathways GO:0007165| signal transduction CD86;CCR2 GO:0016032| viral reproduction CD86;CD80;CCR2 GO:0006955| immune response CD86;CCR2 25138:[DB01281 DB07060] DB01281|Abatacept CD80;CD86 DB07060|3-(INDOL-3-YL) LACTATE HAO1 common genes common pathways 25139:[DB01281 DB08834] DB01281|Abatacept CD80;CD86 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways 25140:[DB01281 DB07843] DB01281|Abatacept CD80;CD86 DB07843|5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 25141:[DB01281 DB03153] DB01281|Abatacept CD80;CD86 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 25142:[DB01281 DB12651] DB01281|Abatacept CD80;CD86 DB12651|Bardoxolone CASP8 common genes common pathways GO:0016032| viral reproduction CD80;CASP8;CD86 25143:[DB01281 DB00298] DB01281|Abatacept CD80;CD86 DB00298|Dapiprazole ADRA1A;ADRA1D;ADRA1B common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;CD86 GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0007165| signal transduction ADRA1B;ADRA1D;ADRA1A;CD86 25144:[DB01281 DB12489] DB01281|Abatacept CD80;CD86 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways 25145:[DB01281 DB00698] DB01281|Abatacept CD80;CD86 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways 25146:[DB01281 DB00145] DB01281|Abatacept CD80;CD86 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0008284| positive regulation of cell proliferation SHMT2;CD86 GO:0007165| signal transduction GPR18;CD86 25147:[DB01281 DB08892] DB01281|Abatacept CD80;CD86 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways GO:0007165| signal transduction GABBR1;CD86;GABBR2 25148:[DB01281 DB04410] DB01281|Abatacept CD80;CD86 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways 25149:[DB01281 DB00830] DB01281|Abatacept CD80;CD86 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways 25150:[DB01281 DB11805] DB01281|Abatacept CD80;CD86 DB11805|Saracatinib CYP3A4 common genes common pathways 25151:[DB01281 DB14017] DB01281|Abatacept CD80;CD86 DB14017|H3B-8800 SF3B1 common genes common pathways 25152:[DB01281 DB06346] DB01281|Abatacept CD80;CD86 DB06346|Fiboflapon ALOX5AP common genes common pathways 25153:[DB01281 DB03918] DB01281|Abatacept CD80;CD86 DB03918|6S-5,6,7,8-Tetrahydrobiopterin NOS3 common genes common pathways 25154:[DB01281 DB00052] DB01281|Abatacept CD80;CD86 DB00052|Somatotropin GHR;PRLR common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation GHR;CD80 25155:[DB01281 DB05967] DB01281|Abatacept CD80;CD86 DB05967|ANZ-100 KISS1R common genes common pathways GO:0007165| signal transduction KISS1R;CD86 25156:[DB01281 DB12243] DB01281|Abatacept CD80;CD86 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways 25157:[DB01281 DB05448] DB01281|Abatacept CD80;CD86 DB05448|PX-12 TXNRD1 common genes common pathways GO:0007165| signal transduction TXNRD1;CD86 25158:[DB01281 DB07151] DB01281|Abatacept CD80;CD86 DB07151|4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one PIM1 common genes common pathways 25159:[DB01281 DB04282] DB01281|Abatacept CD80;CD86 DB04282|2-deoxy-2-fluoro-α-D-glucose LCT common genes common pathways 25160:[DB01281 DB11830] DB01281|Abatacept CD80;CD86 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways GO:0016032| viral reproduction HDAC1;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent HDAC1;CD86;CD80;HDAC2 GO:0008284| positive regulation of cell proliferation HDAC1;CD86;HDAC2 25161:[DB01281 DB02080] DB01281|Abatacept CD80;CD86 DB02080|1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene PLA2G2A;lepB;TTPA common genes common pathways 25162:[DB01281 DB03298] DB01281|Abatacept CD80;CD86 DB03298|Phenylphosphate SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0002376| immune system process CD86;SRC GO:0016032| viral reproduction CD86;SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0035556| intracellular signal transduction CD80;SRC GO:0007165| signal transduction SRC;CD86 25163:[DB01281 DB05532] DB01281|Abatacept CD80;CD86 DB05532|BMS-488043 FFAR4 common genes common pathways GO:0007165| signal transduction CD86;FFAR4 25164:[DB01281 DB05449] DB01281|Abatacept CD80;CD86 DB05449|FM-VP4 ABCB1 common genes common pathways 25165:[DB01281 DB07180] DB01281|Abatacept CD80;CD86 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways 25166:[DB01281 DB09348] DB01281|Abatacept CD80;CD86 DB09348|Propiolactone ALB common genes common pathways 25167:[DB01281 DB14001] DB01281|Abatacept CD80;CD86 DB14001|alpha-Tocopherol succinate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0007165| signal transduction CD86;NR1I2;PRKCB GO:0035556| intracellular signal transduction PRKCB;CD80;DGKA;HMOX1;PRKCA GO:0002376| immune system process PRKCB;CD86 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CD86;CD80;SEC14L2 GO:0002250| adaptive immune response CD86;PRKCB 25168:[DB01281 DB04988] DB01281|Abatacept CD80;CD86 DB04988|IGN311 EGFR;ERBB2 common genes common pathways GO:0035556| intracellular signal transduction EGFR;CD80 GO:0046718| entry of virus into host cell CD80;EGFR;CD86 GO:0007165| signal transduction ERBB2;EGFR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;EGFR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;EGFR;CD80;ERBB2 GO:0008284| positive regulation of cell proliferation CD86;EGFR GO:0046854| phosphatidylinositol phosphorylation EGFR;CD86;CD80;ERBB2 25169:[DB01281 DB08058] DB01281|Abatacept CD80;CD86 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 25170:[DB01281 DB01760] DB01281|Abatacept CD80;CD86 DB01760|2-Methoxy-3-Isopropylpyrazine LCN9 common genes common pathways 25171:[DB01281 DB07739] DB01281|Abatacept CD80;CD86 DB07739|(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE PNMT common genes common pathways 25172:[DB01281 DB09539] DB01281|Abatacept CD80;CD86 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways 25173:[DB01281 DB03953] DB01281|Abatacept CD80;CD86 DB03953|L-Thiocitrulline NOS2 common genes common pathways 25174:[DB01281 DB06733] DB01281|Abatacept CD80;CD86 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 25175:[DB01281 DB02933] DB01281|Abatacept CD80;CD86 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 25176:[DB01281 DB02056] DB01281|Abatacept CD80;CD86 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0007165| signal transduction PTGDR2;CD86 GO:0006955| immune response CD86;PTGDR2 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;AKR1C3;CD86 GO:0008284| positive regulation of cell proliferation AKR1C3;CD86 25177:[DB01281 DB01294] DB01281|Abatacept CD80;CD86 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 25178:[DB01281 DB04723] DB01281|Abatacept CD80;CD86 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways 25179:[DB01281 DB04821] DB01281|Abatacept CD80;CD86 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways 25180:[DB01281 DB04653] DB01281|Abatacept CD80;CD86 DB04653|CBZ-LEU-LEU-TYR-CH2F CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CAPN1 25181:[DB01281 DB02565] DB01281|Abatacept CD80;CD86 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways 25182:[DB01281 DB01022] DB01281|Abatacept CD80;CD86 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 25183:[DB01281 DB03166] DB01281|Abatacept CD80;CD86 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways 25184:[DB01281 DB07616] DB01281|Abatacept CD80;CD86 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways GO:0007165| signal transduction CD86;HPGDS 25185:[DB01281 DB07136] DB01281|Abatacept CD80;CD86 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 25186:[DB01281 DB04576] DB01281|Abatacept CD80;CD86 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways 25187:[DB01281 DB02337] DB01281|Abatacept CD80;CD86 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 25188:[DB01281 DB14641] DB01281|Abatacept CD80;CD86 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0007165| signal transduction ESR2;CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;CD80;ESR1 25189:[DB01281 DB00116] DB01281|Abatacept CD80;CD86 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0008284| positive regulation of cell proliferation SHMT2;CD86 25190:[DB01281 DB02158] DB01281|Abatacept CD80;CD86 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 25191:[DB01281 DB00767] DB01281|Abatacept CD80;CD86 DB00767|Benzquinamide HRH1;CHRM4;CHRM1;CHRM5;CHRM2;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM3;CD86;CHRM4;CHRM2;CHRM1;HRH1;CHRM5 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 25192:[DB01281 DB05033] DB01281|Abatacept CD80;CD86 DB05033|INCB7839 ADAM9 common genes common pathways 25193:[DB01281 DB13998] DB01281|Abatacept CD80;CD86 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 GO:0008284| positive regulation of cell proliferation CD86;F2;CALR 25194:[DB01281 DB08835] DB01281|Abatacept CD80;CD86 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways 25195:[DB01281 DB05460] DB01281|Abatacept CD80;CD86 DB05460|Ezatiostat GSTP1 common genes common pathways 25196:[DB01281 DB03288] DB01281|Abatacept CD80;CD86 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways 25197:[DB01281 DB05299] DB01281|Abatacept CD80;CD86 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways GO:0002376| immune system process IL2;CD86 GO:0002250| adaptive immune response IL2;CD86 GO:0008284| positive regulation of cell proliferation IL2;CD86 GO:0006955| immune response CD86;IL2 25198:[DB01281 DB04877] DB01281|Abatacept CD80;CD86 DB04877|Voacamine ABCB1 common genes common pathways 25199:[DB01281 DB00611] DB01281|Abatacept CD80;CD86 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0006955| immune response CD86;OPRK1;OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;OPRK1;CD86 25200:[DB01281 DB03114] DB01281|Abatacept CD80;CD86 DB03114|PAS219 SRC common genes common pathways GO:0007165| signal transduction CD86;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction SRC;CD80;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;SRC GO:0051897| positive regulation of protein kinase B signaling cascade CD80;SRC;CD86 25201:[DB01281 DB02105] DB01281|Abatacept CD80;CD86 DB02105|3,5-Dinitrocatechol COMT common genes common pathways 25202:[DB01281 DB04960] DB01281|Abatacept CD80;CD86 DB04960|Tipifarnib FNTB common genes common pathways 25203:[DB01281 DB09072] DB01281|Abatacept CD80;CD86 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways 25204:[DB01281 DB03203] DB01281|Abatacept CD80;CD86 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;PVR GO:0016032| viral reproduction CD86;PVR;CD80 25205:[DB01281 DB13988] DB01281|Abatacept CD80;CD86 DB13988|SB-269970 HTR7 common genes common pathways GO:0007165| signal transduction HTR7;CD86 25206:[DB01281 DB04350] DB01281|Abatacept CD80;CD86 DB04350|Argadin CHIT1 common genes common pathways GO:0006955| immune response CD86;CHIT1 25207:[DB01281 DB07358] DB01281|Abatacept CD80;CD86 DB07358|2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 25208:[DB01281 DB11726] DB01281|Abatacept CD80;CD86 DB11726|Encenicline CHRNA7 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 GO:0007165| signal transduction CD86;CHRNA7 25209:[DB01281 DB02908] DB01281|Abatacept CD80;CD86 DB02908|RU78783 SRC common genes common pathways GO:0007165| signal transduction CD86;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD80;SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;SRC;CD86 25210:[DB01281 DB01055] DB01281|Abatacept CD80;CD86 DB01055|Mimosine SHMT1;CCL2;TYR common genes common pathways GO:0006955| immune response CD86;CCL2 GO:0007165| signal transduction CD86;CCL2 25211:[DB01281 DB07841] DB01281|Abatacept CD80;CD86 DB07841|Geranylgeranyl diphosphate FNTA;PGGT1B;FNTB;GGPS1;FDPS;RABGGTA;RABGGTB common genes common pathways GO:0016032| viral reproduction CD86;CD80;FDPS GO:0008284| positive regulation of cell proliferation CD86;PGGT1B 25212:[DB01281 DB04657] DB01281|Abatacept CD80;CD86 DB04657|Carboxin SDHA common genes common pathways 25213:[DB01281 DB00779] DB01281|Abatacept CD80;CD86 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways 25214:[DB01281 DB05928] DB01281|Abatacept CD80;CD86 DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;NR1I2;CD80 GO:0007165| signal transduction NR1I2;CD86 25215:[DB01281 DB01086] DB01281|Abatacept CD80;CD86 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes common pathways 25216:[DB01281 DB00858] DB01281|Abatacept CD80;CD86 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 25217:[DB01281 DB01562] DB01281|Abatacept CD80;CD86 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways 25218:[DB01281 DB08042] DB01281|Abatacept CD80;CD86 DB08042|N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0016032| viral reproduction CD86;KDR;CD80 GO:0008284| positive regulation of cell proliferation CD86;KDR 25219:[DB01281 DB06554] DB01281|Abatacept CD80;CD86 DB06554|Gaboxadol SLC36A1 common genes common pathways 25220:[DB01281 DB08363] DB01281|Abatacept CD80;CD86 DB08363|1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine TP53 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent TP53;CD86;CD80 GO:0016032| viral reproduction CD86;TP53;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TP53;CD80 25221:[DB01281 DB02853] DB01281|Abatacept CD80;CD86 DB02853|D-Proline SLC36A1 common genes common pathways 25222:[DB01281 DB04275] DB01281|Abatacept CD80;CD86 DB04275|N-acetylserotonin SPR common genes common pathways 25223:[DB01281 DB00016] DB01281|Abatacept CD80;CD86 DB00016|Erythropoietin EPOR common genes common pathways GO:0007165| signal transduction CD86;EPOR 25224:[DB01281 DB13875] DB01281|Abatacept CD80;CD86 DB13875|Harmaline HNMT common genes common pathways 25225:[DB01281 DB06704] DB01281|Abatacept CD80;CD86 DB06704|Iobenguane SLC6A2 common genes common pathways 25226:[DB01281 DB06226] DB01281|Abatacept CD80;CD86 DB06226|Nelipepimut-S HLA-A;HLA-A common genes common pathways GO:0006955| immune response HLA-A;CD86 GO:0016032| viral reproduction HLA-A;CD86;CD80 GO:0002376| immune system process HLA-A;CD86 25227:[DB01281 DB03121] DB01281|Abatacept CD80;CD86 DB03121|(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid PLA2G2A common genes common pathways 25228:[DB01281 DB07757] DB01281|Abatacept CD80;CD86 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways GO:0007165| signal transduction CD86;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;ESR2 25229:[DB01281 DB04367] DB01281|Abatacept CD80;CD86 DB04367|Debromohymenialdisine TNK2;CLK1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;TNK2 GO:0007165| signal transduction TNK2;CD86 25230:[DB01281 DB09322] DB01281|Abatacept CD80;CD86 DB09322|Zinc sulfate ALPPL2 common genes common pathways 25231:[DB01281 DB08553] DB01281|Abatacept CD80;CD86 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways GO:0007165| signal transduction BRAF;CD86 GO:0035556| intracellular signal transduction BRAF;CD80 25232:[DB01281 DB07544] DB01281|Abatacept CD80;CD86 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways 25233:[DB01281 DB04178] DB01281|Abatacept CD80;CD86 DB04178|Di-Stearoyl-3-Sn-Phosphatidylcholine BPI;SLC25A4 common genes common pathways GO:0016032| viral reproduction CD86;SLC25A4;CD80 GO:0006955| immune response CD86;BPI 25234:[DB01281 DB00142] DB01281|Abatacept CD80;CD86 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0007165| signal transduction GRIA2;GRM4;GRM8;GRM7;GRIA1;CD86;GRM1 25235:[DB01281 DB07444] DB01281|Abatacept CD80;CD86 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways GO:0035556| intracellular signal transduction CD80;DAPK1 GO:0007165| signal transduction CD86;DAPK1 25236:[DB01281 DB11842] DB01281|Abatacept CD80;CD86 DB11842|Angiotensin II AGTR1 common genes common pathways GO:0007165| signal transduction CD86;AGTR1 25237:[DB01281 DB00508] DB01281|Abatacept CD80;CD86 DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HTR2B;CHRM1 GO:0007165| signal transduction DRD1;CHRM2;CHRM1;DRD2;CD86;HTR2B GO:0035556| intracellular signal transduction DRD2;CD80 25238:[DB01281 DB13173] DB01281|Abatacept CD80;CD86 DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0007165| signal transduction CD86;IGF2R 25239:[DB01281 DB06680] DB01281|Abatacept CD80;CD86 DB06680|Asoprisnil PGR common genes common pathways GO:0007165| signal transduction CD86;PGR 25240:[DB01281 DB00486] DB01281|Abatacept CD80;CD86 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0007165| signal transduction CD86;CNR2;CNR1 GO:0006955| immune response CD86;CNR2 25241:[DB01281 DB05120] DB01281|Abatacept CD80;CD86 DB05120|AT1391 INSR common genes common pathways GO:0035556| intracellular signal transduction CD80;INSR GO:0008284| positive regulation of cell proliferation CD86;INSR GO:0045893| positive regulation of transcription, DNA-dependent CD80;INSR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;INSR;CD80 25242:[DB01281 DB09207] DB01281|Abatacept CD80;CD86 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction DRD3;CD86;DRD2 GO:0008284| positive regulation of cell proliferation CD86;DRD3 25243:[DB01281 DB04094] DB01281|Abatacept CD80;CD86 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways 25244:[DB01281 DB04719] DB01281|Abatacept CD80;CD86 DB04719|DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE CSNK2A1 common genes common pathways GO:0007165| signal transduction CD86;CSNK2A1 GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 25245:[DB01281 DB00198] DB01281|Abatacept CD80;CD86 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways 25246:[DB01281 DB04462] DB01281|Abatacept CD80;CD86 DB04462|Tetrabromo-2-Benzotriazole CSNK2A1 common genes common pathways GO:0007165| signal transduction CSNK2A1;CD86 GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 25247:[DB01281 DB05996] DB01281|Abatacept CD80;CD86 DB05996|Glembatumumab vedotin GPNMB common genes common pathways GO:0007165| signal transduction CD86;GPNMB 25248:[DB01281 DB04197] DB01281|Abatacept CD80;CD86 DB04197|Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0002250| adaptive immune response CD86;ARG1 GO:0002376| immune system process CD86;ARG1 25249:[DB01281 DB13894] DB01281|Abatacept CD80;CD86 DB13894|Agkistrodon piscivorus antivenin PLA2G10 common genes common pathways 25250:[DB01281 DB05915] DB01281|Abatacept CD80;CD86 DB05915|MYO-029 MSTN common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;MSTN 25251:[DB01281 DB03381] DB01281|Abatacept CD80;CD86 DB03381|Hexadecanal RHO;DBI common genes common pathways GO:0007165| signal transduction CD86;RHO 25252:[DB01281 DB07981] DB01281|Abatacept CD80;CD86 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways 25253:[DB01281 DB09285] DB01281|Abatacept CD80;CD86 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 GO:0006955| immune response CD86;LTB4R GO:0007165| signal transduction LTB4R;TBXA2R;CD86 25254:[DB01281 DB03048] DB01281|Abatacept CD80;CD86 DB03048|6-Carboxymethyluracil DPYD common genes common pathways 25255:[DB01281 DB01106] DB01281|Abatacept CD80;CD86 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways GO:0007165| signal transduction HRH1;NTSR2;CD86 25256:[DB01281 DB01210] DB01281|Abatacept CD80;CD86 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0007165| signal transduction ADRB1;CD86;ADRB2 25257:[DB01281 DB02556] DB01281|Abatacept CD80;CD86 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:0007165| signal transduction CD86;CRH GO:0008284| positive regulation of cell proliferation CD86;CRH 25258:[DB01281 DB02570] DB01281|Abatacept CD80;CD86 DB02570|PD150606 CAPNS1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPNS1;CD86 25259:[DB01281 DB07960] DB01281|Abatacept CD80;CD86 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways 25260:[DB01281 DB02266] DB01281|Abatacept CD80;CD86 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0007165| signal transduction CD86;PPARG;AR GO:0008284| positive regulation of cell proliferation CD86;AR;PTGS2;AKR1C3 GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;PPARA;CD86;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;CD80;CD86 25261:[DB01281 DB02377] DB01281|Abatacept CD80;CD86 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0006955| immune response PNP;CD86 25262:[DB01281 DB12305] DB01281|Abatacept CD80;CD86 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways 25263:[DB01281 DB01209] DB01281|Abatacept CD80;CD86 DB01209|Dezocine OPRM1;OPRK1 common genes common pathways GO:0006955| immune response OPRK1;CD86 GO:0007165| signal transduction OPRK1;CD86;OPRM1 25264:[DB01281 DB01619] DB01281|Abatacept CD80;CD86 DB01619|Phenindamine HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 25265:[DB01281 DB05892] DB01281|Abatacept CD80;CD86 DB05892|RI 624 NGF common genes common pathways 25266:[DB01281 DB07425] DB01281|Abatacept CD80;CD86 DB07425|Sobetirome THRB common genes common pathways 25267:[DB01281 DB02942] DB01281|Abatacept CD80;CD86 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 25268:[DB01281 DB00973] DB01281|Abatacept CD80;CD86 DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0016032| viral reproduction CD86;CD80;ANPEP GO:0007165| signal transduction CD86;ANPEP GO:0046718| entry of virus into host cell CD86;ANPEP;CD80 25269:[DB01281 DB11723] DB01281|Abatacept CD80;CD86 DB11723|Dutogliptin DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0046718| entry of virus into host cell CD80;DPP4;CD86 25270:[DB01281 DB04153] DB01281|Abatacept CD80;CD86 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways 25271:[DB01281 DB05740] DB01281|Abatacept CD80;CD86 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 GO:0007165| signal transduction CHRNA7;CHRNA4;CHRNA2;CHRNA9;CHRNB2;CD86;CHRNA10 25272:[DB01281 DB00399] DB01281|Abatacept CD80;CD86 DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 common genes common pathways GO:0016032| viral reproduction CD86;CD80;FDPS 25273:[DB01281 DB06362] DB01281|Abatacept CD80;CD86 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 25274:[DB01281 DB04768] DB01281|Abatacept CD80;CD86 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 25275:[DB01281 DB03052] DB01281|Abatacept CD80;CD86 DB03052|Dazoxiben TBXAS1 common genes common pathways 25276:[DB01281 DB00437] DB01281|Abatacept CD80;CD86 DB00437|Allopurinol XDH;AOX1;XDH;SLC22A8;SLC22A7 common genes common pathways 25277:[DB01281 DB05241] DB01281|Abatacept CD80;CD86 DB05241|XL765 PIK3CA;PIK3CG;PIK3CD;PIK3CB;MTOR common genes common pathways GO:0002250| adaptive immune response PIK3CD;PIK3CG;CD86;PIK3CB;PIK3CA GO:0051897| positive regulation of protein kinase B signaling cascade CD86;MTOR;PIK3CD;PIK3CG;PIK3CA;CD80;PIK3CB GO:0046854| phosphatidylinositol phosphorylation PIK3CA;CD80;PIK3CB;CD86;PIK3CD;PIK3CG GO:0002376| immune system process PIK3CD;PIK3CG;CD86 GO:0031295| T cell costimulation CD80;PIK3CA;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;CD80 GO:0007165| signal transduction PIK3CB;CD86;MTOR;PIK3CD 25278:[DB01281 DB00473] DB01281|Abatacept CD80;CD86 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 25279:[DB01281 DB02467] DB01281|Abatacept CD80;CD86 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways 25280:[DB01281 DB01046] DB01281|Abatacept CD80;CD86 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways 25281:[DB01281 DB08103] DB01281|Abatacept CD80;CD86 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways 25282:[DB01281 DB03147] DB01281|Abatacept CD80;CD86 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;NOS1;CD80 GO:0016032| viral reproduction CD80;TPR;CD86 GO:0007165| signal transduction TXNRD1;CD86 25283:[DB01281 DB00235] DB01281|Abatacept CD80;CD86 DB00235|Milrinone PDE3A common genes common pathways GO:0007165| signal transduction CD86;PDE3A 25284:[DB01281 DB03485] DB01281|Abatacept CD80;CD86 DB03485|Alpha-D-Fucose LTF common genes common pathways GO:0002376| immune system process LTF;CD86 25285:[DB01281 DB14562] DB01281|Abatacept CD80;CD86 DB14562|Andexanet alfa TFPI common genes common pathways 25286:[DB01281 DB08824] DB01281|Abatacept CD80;CD86 DB08824|Ioflupane I-123 SLC6A3 common genes common pathways 25287:[DB01281 DB05252] DB01281|Abatacept CD80;CD86 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways 25288:[DB01281 DB07168] DB01281|Abatacept CD80;CD86 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways GO:0007165| signal transduction CAMK2B;CD86 GO:0035556| intracellular signal transduction CAMK2B;CD80 25289:[DB01281 DB01927] DB01281|Abatacept CD80;CD86 DB01927|Duroquinone NQO1 common genes common pathways 25290:[DB01281 DB08995] DB01281|Abatacept CD80;CD86 DB08995|Diosmin AHR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;AHR;CD86 25291:[DB01281 DB01390] DB01281|Abatacept CD80;CD86 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways 25292:[DB01281 DB02545] DB01281|Abatacept CD80;CD86 DB02545|Fexaramine NR1H4 common genes common pathways GO:0007165| signal transduction NR1H4;CD86 GO:0002376| immune system process NR1H4;CD86 25293:[DB01281 DB03619] DB01281|Abatacept CD80;CD86 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction CD86;SLC10A1;CD80 GO:0046718| entry of virus into host cell CD86;SLC10A1;CD80 GO:0007165| signal transduction NR1H4;CD86;GPBAR1 GO:0002376| immune system process CD86;NR1H4 25294:[DB01281 DB06374] DB01281|Abatacept CD80;CD86 DB06374|Elacestrant ESR1 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 25295:[DB01281 DB06082] DB01281|Abatacept CD80;CD86 DB06082|PX-478 HIF1A common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent HIF1A;CD80;CD86 GO:0007165| signal transduction HIF1A;CD86 25296:[DB01281 DB01723] DB01281|Abatacept CD80;CD86 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways 25297:[DB01281 DB01407] DB01281|Abatacept CD80;CD86 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0007165| signal transduction ADRB2;ADRB1;ADRB3;CD86 GO:0006955| immune response CD86;TNF GO:0045893| positive regulation of transcription, DNA-dependent CD80;TNF;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 25298:[DB01281 DB01439] DB01281|Abatacept CD80;CD86 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response CD86;OPRK1;OPRD1 GO:0007165| signal transduction OPRK1;CD86;OPRD1;OPRM1 25299:[DB01281 DB07497] DB01281|Abatacept CD80;CD86 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways 25300:[DB01281 DB03379] DB01281|Abatacept CD80;CD86 DB03379|2-Carboxyethylphosphonic Acid TPI1 common genes common pathways 25301:[DB01281 DB07707] DB01281|Abatacept CD80;CD86 DB07707|(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 GO:0007165| signal transduction CD86;ESR1 25302:[DB01281 DB13146] DB01281|Abatacept CD80;CD86 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0016032| viral reproduction SLC1A5;CD80;CD86 GO:0046718| entry of virus into host cell SLC1A5;CD80;CD86 GO:0007165| signal transduction GRIA2;CD86;GRIA1 25303:[DB01281 DB08346] DB01281|Abatacept CD80;CD86 DB08346|(5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE HSP90AB1 common genes common pathways 25304:[DB01281 DB07678] DB01281|Abatacept CD80;CD86 DB07678|(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 25305:[DB01281 DB02169] DB01281|Abatacept CD80;CD86 DB02169|9,10-Deepithio-9,10-Didehydroacanthifolicin PPP1CC common genes common pathways 25306:[DB01281 DB05790] DB01281|Abatacept CD80;CD86 DB05790|SR 140333 TACR1 common genes common pathways GO:0007165| signal transduction CD86;TACR1 25307:[DB01281 DB09338] DB01281|Abatacept CD80;CD86 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways 25308:[DB01281 DB07315] DB01281|Abatacept CD80;CD86 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways 25309:[DB01281 DB09418] DB01281|Abatacept CD80;CD86 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways 25310:[DB01281 DB04636] DB01281|Abatacept CD80;CD86 DB04636|Glutamine t-butyl ester QPCT common genes common pathways 25311:[DB01281 DB04676] DB01281|Abatacept CD80;CD86 DB04676|Dansyllysine IGHA2 common genes common pathways GO:0006955| immune response CD86;IGHA2 GO:0002250| adaptive immune response IGHA2;CD86 GO:0002376| immune system process CD86;IGHA2 25312:[DB01281 DB07082] DB01281|Abatacept CD80;CD86 DB07082|1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL NR1H2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;NR1H2 25313:[DB01281 DB05254] DB01281|Abatacept CD80;CD86 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 25314:[DB01281 DB03276] DB01281|Abatacept CD80;CD86 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways GO:0031295| T cell costimulation CD80;CD86;GRB2 GO:0046854| phosphatidylinositol phosphorylation GRB2;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;GRB2;CD86 GO:0016032| viral reproduction GRB2;CD86;CD80 25315:[DB01281 DB01127] DB01281|Abatacept CD80;CD86 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent CD86;NR1I2;CD80 25316:[DB01281 DB02552] DB01281|Abatacept CD80;CD86 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0016032| viral reproduction CD86;CD80;FDPS 25317:[DB01281 DB08699] DB01281|Abatacept CD80;CD86 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways GO:0035556| intracellular signal transduction CD80;CAMK2G 25318:[DB01281 DB07916] DB01281|Abatacept CD80;CD86 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways GO:0007165| signal transduction CD86;CASP1 25319:[DB01281 DB03800] DB01281|Abatacept CD80;CD86 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways 25320:[DB01281 DB03956] DB01281|Abatacept CD80;CD86 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways GO:0035556| intracellular signal transduction CD80;PLCD1 GO:0007165| signal transduction CD86;PLCD1 25321:[DB01281 DB02673] DB01281|Abatacept CD80;CD86 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways 25322:[DB01281 DB07356] DB01281|Abatacept CD80;CD86 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;DPP4;CD86 25323:[DB01281 DB05052] DB01281|Abatacept CD80;CD86 DB05052|MF101 ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR2;CD80 GO:0007165| signal transduction ESR2;CD86 25324:[DB01281 DB06243] DB01281|Abatacept CD80;CD86 DB06243|Eflornithine ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation ODC1;CD86 25325:[DB01281 DB03032] DB01281|Abatacept CD80;CD86 DB03032|S-Octylglutathione GSTM4 common genes common pathways 25326:[DB01281 DB03628] DB01281|Abatacept CD80;CD86 DB03628|ISO24 SRC common genes common pathways GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80;CD86 GO:0007165| signal transduction SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD86;SRC;CD80 25327:[DB01281 DB04789] DB01281|Abatacept CD80;CD86 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways 25328:[DB01281 DB02979] DB01281|Abatacept CD80;CD86 DB02979|N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane NOS3 common genes common pathways 25329:[DB01281 DB06448] DB01281|Abatacept CD80;CD86 DB06448|Lonafarnib FNTA;IGFBP3 common genes common pathways 25330:[DB01281 DB01452] DB01281|Abatacept CD80;CD86 DB01452|Diamorphine OPRM1;OPRK1;OPRD1;CES1 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;OPRK1;CD86 GO:0006955| immune response OPRD1;CD86;OPRK1 25331:[DB01281 DB01363] DB01281|Abatacept CD80;CD86 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ADRA2A GO:0007165| signal transduction ADRB1;ADRA2A;ADRB3;CD86;ADRA2C;ADRB2;ADRA2B 25332:[DB01281 DB04540] DB01281|Abatacept CD80;CD86 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes common pathways GO:0007165| signal transduction VDR;NR1I3;CD86 GO:0006955| immune response CLEC4E;CD86 GO:0002376| immune system process CD86;CLEC4E GO:0045893| positive regulation of transcription, DNA-dependent RORA;CD86;CD80 25333:[DB01281 DB12445] DB01281|Abatacept CD80;CD86 DB12445|Nitroaspirin PTGS1 common genes common pathways 25334:[DB01281 DB02381] DB01281|Abatacept CD80;CD86 DB02381|nor-NOHA ARG1 common genes common pathways GO:0002376| immune system process CD86;ARG1 GO:0002250| adaptive immune response ARG1;CD86 25335:[DB01281 DB14540] DB01281|Abatacept CD80;CD86 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0045627| positive regulation of T-helper 1 cell differentiation ANXA1;CD80 GO:0006955| immune response CD86;CYP11B1 GO:0007165| signal transduction ANXA1;CD86;NR3C1 GO:0002250| adaptive immune response CD86;ANXA1 GO:0002376| immune system process CD86;ANXA1 25336:[DB01281 DB01369] DB01281|Abatacept CD80;CD86 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways 25337:[DB01281 DB05301] DB01281|Abatacept CD80;CD86 DB05301|LAX-101 PLD1;CASP1 common genes common pathways GO:0007165| signal transduction CD86;CASP1 25338:[DB01281 DB00557] DB01281|Abatacept CD80;CD86 DB00557|Hydroxyzine HRH1;CYP2D6 common genes common pathways GO:0007165| signal transduction CD86;HRH1 25339:[DB01281 DB01351] DB01281|Abatacept CD80;CD86 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0007165| signal transduction CD86;GABRA5;CHRNA4;GRIA2;CHRNA7;GABRA6 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 25340:[DB01281 DB07421] DB01281|Abatacept CD80;CD86 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD86;AR;CD80 GO:0008284| positive regulation of cell proliferation CD86;AR 25341:[DB01281 DB03088] DB01281|Abatacept CD80;CD86 DB03088|Pidolic Acid VEGFA;AMY2A;IGLC1;TFF2;cycA;ADAM28;KRTAP5-2;HCRT;CCL8;AMY2B;ANG;AMY1A;AMY2A common genes common pathways GO:0002250| adaptive immune response IGLC1;CD86 GO:0008284| positive regulation of cell proliferation CD86;VEGFA GO:0002376| immune system process CD86;IGLC1 GO:0006955| immune response IGLC1;CD86;CCL8 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA GO:0007165| signal transduction CD86;CCL8 25342:[DB01281 DB08173] DB01281|Abatacept CD80;CD86 DB08173|5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 25343:[DB01281 DB00435] DB01281|Abatacept CD80;CD86 DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;GUCY1A2 GO:0035556| intracellular signal transduction CD80;GUCY1A2 GO:0002376| immune system process CD86;IDO1 25344:[DB01281 DB05509] DB01281|Abatacept CD80;CD86 DB05509|LI-301 OPRM1;HTR1A common genes common pathways GO:0007165| signal transduction CD86;OPRM1;HTR1A GO:0008284| positive regulation of cell proliferation CD86;HTR1A 25345:[DB01281 DB13872] DB01281|Abatacept CD80;CD86 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0007165| signal transduction CD86;GABRA5 25346:[DB01281 DB04741] DB01281|Abatacept CD80;CD86 DB04741|Myxothiazol UQCRC1 common genes common pathways 25347:[DB01281 DB14503] DB01281|Abatacept CD80;CD86 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0046718| entry of virus into host cell CD80;SLC20A2;CD86 GO:0007165| signal transduction CD86;SLC20A1 GO:0016032| viral reproduction CD86;SLC20A2;CD80 25348:[DB01281 DB05984] DB01281|Abatacept CD80;CD86 DB05984|RAF-265 KDR;BRAF common genes common pathways GO:0016032| viral reproduction CD86;KDR;CD80 GO:0035556| intracellular signal transduction BRAF;CD80 GO:0007165| signal transduction BRAF;CD86 GO:0008284| positive regulation of cell proliferation CD86;KDR 25349:[DB01281 DB02029] DB01281|Abatacept CD80;CD86 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways 25350:[DB01281 DB11601] DB01281|Abatacept CD80;CD86 DB11601|Tuberculin Purified Protein Derivative TLR2 common genes common pathways GO:0006955| immune response CD86;TLR2 GO:0007165| signal transduction TLR2;CD86 GO:0002376| immune system process CD86;TLR2 25351:[DB01281 DB03896] DB01281|Abatacept CD80;CD86 DB03896|Triphosphoric acid PAPOLA common genes common pathways 25352:[DB01281 DB06190] DB01281|Abatacept CD80;CD86 DB06190|Solabegron ADRB3 common genes common pathways GO:0007165| signal transduction CD86;ADRB3 25353:[DB01281 DB06787] DB01281|Abatacept CD80;CD86 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CHRM3;CD86;CHRM4;CHRM2;CHRM1 25354:[DB01281 DB03860] DB01281|Abatacept CD80;CD86 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;ESR2 GO:0007165| signal transduction ESR2;CD86 25355:[DB01281 DB06412] DB01281|Abatacept CD80;CD86 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0007165| signal transduction AR;CD86 25356:[DB01281 DB01651] DB01281|Abatacept CD80;CD86 DB01651|Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside APCS common genes common pathways 25357:[DB01281 DB02559] DB01281|Abatacept CD80;CD86 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways 25358:[DB01281 DB02222] DB01281|Abatacept CD80;CD86 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways GO:0006955| immune response CD86;PNP 25359:[DB01281 DB07111] DB01281|Abatacept CD80;CD86 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 25360:[DB01281 DB00707] DB01281|Abatacept CD80;CD86 DB00707|Porfimer sodium LDLR;FCGR1A common genes common pathways GO:0007165| signal transduction CD86;FCGR1A GO:0046718| entry of virus into host cell CD80;CD86;LDLR GO:0016032| viral reproduction CD80;CD86;LDLR GO:0006955| immune response CD86;FCGR1A GO:0002376| immune system process FCGR1A;CD86 25361:[DB01281 DB06241] DB01281|Abatacept CD80;CD86 DB06241|Clenoliximab CD4 common genes common pathways GO:0045086| positive regulation of interleukin-2 biosynthetic process CD4;CD80;CD86 GO:0002376| immune system process CD4;CD86 GO:0031295| T cell costimulation CD86;CD4;CD80 GO:0002250| adaptive immune response CD86;CD4 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD4;CD86 GO:0007165| signal transduction CD86;CD4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD4;CD80 GO:0006955| immune response CD4;CD86 GO:0016032| viral reproduction CD86;CD80;CD4 25362:[DB01281 DB03135] DB01281|Abatacept CD80;CD86 DB03135|[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid TPI1 common genes common pathways 25363:[DB01281 DB02126] DB01281|Abatacept CD80;CD86 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways 25364:[DB01281 DB01252] DB01281|Abatacept CD80;CD86 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0007165| signal transduction ABCC8;PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD80 25365:[DB01281 DB06262] DB01281|Abatacept CD80;CD86 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0007165| signal transduction ADRA2C;ADRB2;ADRA2B;ADRA1B;ADRA1D;ADRA2A;ADRB3;CD86;ADRA1A;ADRB1 GO:0035556| intracellular signal transduction ADRA1A;ADRA1B;CD80 GO:0008284| positive regulation of cell proliferation CD86;ADRA2A;ADRA1D 25366:[DB01281 DB08214] DB01281|Abatacept CD80;CD86 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways 25367:[DB01281 DB01059] DB01281|Abatacept CD80;CD86 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways 25368:[DB01281 DB02779] DB01281|Abatacept CD80;CD86 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways GO:0009967| positive regulation of signal transduction PTPN11;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade PTPN11;CD86;CD80 GO:0046854| phosphatidylinositol phosphorylation CD86;PTPN11;CD80 GO:0031295| T cell costimulation PTPN11;CD86;CD80 25369:[DB01281 DB08495] DB01281|Abatacept CD80;CD86 DB08495|4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 25370:[DB01281 DB05303] DB01281|Abatacept CD80;CD86 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0006955| immune response TNF;CD86;IL1R1 GO:0007165| signal transduction CD86;IL1R1 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;TNF;CD80 25371:[DB01281 DB07171] DB01281|Abatacept CD80;CD86 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways 25372:[DB01281 DB00002] DB01281|Abatacept CD80;CD86 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;EGFR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CD86;CD80 GO:0002376| immune system process C1QB;C1R;FCGR1A;FCGR2A;CD86;C1QC;C1S;C1QA GO:0046854| phosphatidylinositol phosphorylation CD86;EGFR;CD80 GO:0035556| intracellular signal transduction EGFR;CD80 GO:0006955| immune response FCGR1A;CD86;FCGR3B;FCGR2B;C1R;C1QC;FCGR2C;FCGR3A GO:0016032| viral reproduction CD80;CD86;FCGR2B GO:0007165| signal transduction EGFR;CD86;FCGR1A;FCGR2B;FCGR2C GO:0046718| entry of virus into host cell EGFR;CD86;CD80 25373:[DB01281 DB02701] DB01281|Abatacept CD80;CD86 DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BST1 GO:0007165| signal transduction BST1;CD86 25374:[DB01281 DB09146] DB01281|Abatacept CD80;CD86 DB09146|Iron saccharate HBA1;TF common genes common pathways 25375:[DB01281 DB09449] DB01281|Abatacept CD80;CD86 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction SLC20A2;CD80;CD86 GO:0046718| entry of virus into host cell SLC20A2;CD80;CD86 GO:0007165| signal transduction SLC20A1;CD86 25376:[DB01281 DB00083] DB01281|Abatacept CD80;CD86 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 25377:[DB01281 DB02201] DB01281|Abatacept CD80;CD86 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 25378:[DB01281 DB13269] DB01281|Abatacept CD80;CD86 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways 25379:[DB01281 DB07146] DB01281|Abatacept CD80;CD86 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways GO:0016032| viral reproduction CD80;CD86;LCK GO:0051897| positive regulation of protein kinase B signaling cascade CD86;LCK;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;LCK;CD86 GO:0031295| T cell costimulation CD80;CD86;LCK 25380:[DB01281 DB07975] DB01281|Abatacept CD80;CD86 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways 25381:[DB01281 DB04739] DB01281|Abatacept CD80;CD86 DB04739|4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0035556| intracellular signal transduction CD80;SRC GO:0016032| viral reproduction CD80;SRC;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0007165| signal transduction CD86;SRC 25382:[DB01281 DB08213] DB01281|Abatacept CD80;CD86 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways GO:0035556| intracellular signal transduction CD80;CASP3 25383:[DB01281 DB06370] DB01281|Abatacept CD80;CD86 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways 25384:[DB01281 DB03693] DB01281|Abatacept CD80;CD86 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways GO:0007165| signal transduction CSNK1G2;CD86 25385:[DB01281 DB05041] DB01281|Abatacept CD80;CD86 DB05041|RP101 UPP1;UPP2 common genes common pathways 25386:[DB01281 DB02624] DB01281|Abatacept CD80;CD86 DB02624|Homoserine Lactone SLC9A1 common genes common pathways 25387:[DB01281 DB08595] DB01281|Abatacept CD80;CD86 DB08595|4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 25388:[DB01281 DB11348] DB01281|Abatacept CD80;CD86 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0046718| entry of virus into host cell SLC20A2;CD80;CD86 GO:0007165| signal transduction SRI;SLC20A1;SPARC;CASR;S100A6;CACNA1I;CD86 GO:0016032| viral reproduction CD86;CD80;SLC20A2 GO:0035556| intracellular signal transduction CD80;CAPS GO:0008284| positive regulation of cell proliferation S100B;CASR;S100A13;CIB1;CD86;CALR 25389:[DB01281 DB08230] DB01281|Abatacept CD80;CD86 DB08230|5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE PIM1 common genes common pathways 25390:[DB01281 DB07644] DB01281|Abatacept CD80;CD86 DB07644|5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine DCPS common genes common pathways 25391:[DB01281 DB12191] DB01281|Abatacept CD80;CD86 DB12191|Obatoclax BCL2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BCL2 25392:[DB01281 DB04352] DB01281|Abatacept CD80;CD86 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 25393:[DB01281 DB03626] DB01281|Abatacept CD80;CD86 DB03626|5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways 25394:[DB01281 DB03727] DB01281|Abatacept CD80;CD86 DB03727|Coproporphyrin I UROD common genes common pathways 25395:[DB01281 DB08406] DB01281|Abatacept CD80;CD86 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways 25396:[DB01281 DB06734] DB01281|Abatacept CD80;CD86 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 25397:[DB01281 DB00578] DB01281|Abatacept CD80;CD86 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways 25398:[DB01281 DB07708] DB01281|Abatacept CD80;CD86 DB07708|3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 GO:0007165| signal transduction ESR1;CD86 25399:[DB01281 DB05483] DB01281|Abatacept CD80;CD86 DB05483|PCL-016 UBR4;ZFY common genes common pathways GO:0016032| viral reproduction CD86;UBR4;CD80 25400:[DB01281 DB08461] DB01281|Abatacept CD80;CD86 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR 25401:[DB01281 DB08751] DB01281|Abatacept CD80;CD86 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HRAS GO:0007165| signal transduction HRAS;CD86 25402:[DB01281 DB07172] DB01281|Abatacept CD80;CD86 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARG;CD86 GO:0007165| signal transduction CD86;PPARG 25403:[DB01281 DB09502] DB01281|Abatacept CD80;CD86 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways 25404:[DB01281 DB01070] DB01281|Abatacept CD80;CD86 DB01070|Dihydrotachysterol VDR common genes common pathways GO:0007165| signal transduction VDR;CD86 25405:[DB01281 DB04683] DB01281|Abatacept CD80;CD86 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR5A1;CD80;CD86 25406:[DB01281 DB05505] DB01281|Abatacept CD80;CD86 DB05505|NM-702 TBXAS1 common genes common pathways 25407:[DB01281 DB02763] DB01281|Abatacept CD80;CD86 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways 25408:[DB01281 DB01240] DB01281|Abatacept CD80;CD86 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0007165| signal transduction PTGIR;CD86;P2RY12 25409:[DB01281 DB08847] DB01281|Abatacept CD80;CD86 DB08847|Hydroxyproline SLC36A1 common genes common pathways 25410:[DB01281 DB02383] DB01281|Abatacept CD80;CD86 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways 25411:[DB01281 DB11607] DB01281|Abatacept CD80;CD86 DB11607|Efmoroctocog alfa VWF common genes common pathways 25412:[DB01281 DB00152] DB01281|Abatacept CD80;CD86 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways 25413:[DB01281 DB04964] DB01281|Abatacept CD80;CD86 DB04964|Oregovomab MUC16 common genes common pathways 25414:[DB01281 DB05476] DB01281|Abatacept CD80;CD86 DB05476|WX-UK1 PLAUR common genes common pathways GO:0007165| signal transduction CD86;PLAUR 25415:[DB01281 DB04727] DB01281|Abatacept CD80;CD86 DB04727|N-(4-{4-AMINO-6-[4-(METHYLOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-5-YL}PHENYL)-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA KDR common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;CD86 GO:0016032| viral reproduction CD80;KDR;CD86 25416:[DB01281 DB00097] DB01281|Abatacept CD80;CD86 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways GO:0007165| signal transduction CD86;LHCGR;FSHR 25417:[DB01281 DB03971] DB01281|Abatacept CD80;CD86 DB03971|Acarbose Derived Hexasaccharide AMY2A;AMY2A common genes common pathways 25418:[DB01281 DB00210] DB01281|Abatacept CD80;CD86 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent RXRA;CD86;CD80;RARA GO:0008284| positive regulation of cell proliferation RARA;RARG;PTGS2;RARB;CD86 GO:0045630| positive regulation of T-helper 2 cell differentiation CD86;RARA GO:0016032| viral reproduction CD86;RXRA;CD80 GO:0007165| signal transduction CD86;RARB;RARA 25419:[DB01281 DB07848] DB01281|Abatacept CD80;CD86 DB07848|5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 25420:[DB01281 DB05421] DB01281|Abatacept CD80;CD86 DB05421|CP-122721 TACR1 common genes common pathways GO:0007165| signal transduction CD86;TACR1 25421:[DB01281 DB01155] DB01281|Abatacept CD80;CD86 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways 25422:[DB01281 DB01800] DB01281|Abatacept CD80;CD86 DB01800|N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium ARSA common genes common pathways 25423:[DB01281 DB06921] DB01281|Abatacept CD80;CD86 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 25424:[DB01281 DB05431] DB01281|Abatacept CD80;CD86 DB05431|MLN-977 ALOX5 common genes common pathways 25425:[DB01281 DB02998] DB01281|Abatacept CD80;CD86 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0007165| signal transduction CD86;NR3C2;PGR;AR GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 25426:[DB01281 DB14635] DB01281|Abatacept CD80;CD86 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0007165| signal transduction VDR;CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 25427:[DB01281 DB02813] DB01281|Abatacept CD80;CD86 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways 25428:[DB01281 DB04318] DB01281|Abatacept CD80;CD86 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways 25429:[DB01281 DB02177] DB01281|Abatacept CD80;CD86 DB02177|1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine ITGAL common genes common pathways GO:0007165| signal transduction CD86;ITGAL 25430:[DB01281 DB02142] DB01281|Abatacept CD80;CD86 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways 25431:[DB01281 DB12334] DB01281|Abatacept CD80;CD86 DB12334|Milataxel TUBB1;TUBB common genes common pathways 25432:[DB01281 DB06157] DB01281|Abatacept CD80;CD86 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways 25433:[DB01281 DB08082] DB01281|Abatacept CD80;CD86 DB08082|N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE MAOB common genes common pathways 25434:[DB01281 DB07462] DB01281|Abatacept CD80;CD86 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways 25435:[DB01281 DB09303] DB01281|Abatacept CD80;CD86 DB09303|Evolocumab PCSK9 common genes common pathways 25436:[DB01281 DB01284] DB01281|Abatacept CD80;CD86 DB01284|Tetracosactide MC2R common genes common pathways GO:0007165| signal transduction MC2R;CD86 25437:[DB01281 DB03484] DB01281|Abatacept CD80;CD86 DB03484|L-Alpha-Glycerophosphorylethanolamine ANXA5 common genes common pathways GO:0007165| signal transduction ANXA5;CD86 25438:[DB01281 DB05913] DB01281|Abatacept CD80;CD86 DB05913|OSI-930 KIT;FLT1 common genes common pathways GO:0008284| positive regulation of cell proliferation FLT1;KIT;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;KIT GO:0046854| phosphatidylinositol phosphorylation KIT;CD80;CD86 GO:0035556| intracellular signal transduction CD80;KIT GO:0007165| signal transduction KIT;CD86 25439:[DB01281 DB00438] DB01281|Abatacept CD80;CD86 DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 25440:[DB01281 DB04010] DB01281|Abatacept CD80;CD86 DB04010|2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide PARP1 common genes common pathways 25441:[DB01281 DB06124] DB01281|Abatacept CD80;CD86 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways GO:0007165| signal transduction CAPN3;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CAPN3;CD86 25442:[DB01281 DB12200] DB01281|Abatacept CD80;CD86 DB12200|Tivantinib MET common genes common pathways GO:0007165| signal transduction MET;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;MET;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;MET;CD80 25443:[DB01281 DB06366] DB01281|Abatacept CD80;CD86 DB06366|Pertuzumab ERBB2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade ERBB2;CD80;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;ERBB2;CD80 GO:0007165| signal transduction CD86;ERBB2 25444:[DB01281 DB04590] DB01281|Abatacept CD80;CD86 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F7;CD80 25445:[DB01281 DB05668] DB01281|Abatacept CD80;CD86 DB05668|Palifosfamide DNMT1 common genes common pathways 25446:[DB01281 DB04758] DB01281|Abatacept CD80;CD86 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F7 25447:[DB01281 DB05404] DB01281|Abatacept CD80;CD86 DB05404|AZD 3355 TP53 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent TP53;CD86;CD80 GO:0016032| viral reproduction CD86;TP53;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TP53;CD80 25448:[DB01281 DB06101] DB01281|Abatacept CD80;CD86 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;KDR;FLT4;FLT1 GO:0016032| viral reproduction KDR;CD86;CD80 25449:[DB01281 DB04461] DB01281|Abatacept CD80;CD86 DB04461|Coproporphyrinogen III UROD common genes common pathways 25450:[DB01281 DB07039] DB01281|Abatacept CD80;CD86 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR GO:0007165| signal transduction CD86;AR 25451:[DB01281 DB11059] DB01281|Abatacept CD80;CD86 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways 25452:[DB01281 DB04325] DB01281|Abatacept CD80;CD86 DB04325|Phenethylamine PRSS2;PRSS1 common genes common pathways 25453:[DB01281 DB06973] DB01281|Abatacept CD80;CD86 DB06973|4,4'-PROPANE-2,2-DIYLDIPHENOL ESRRG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;ESRRG 25454:[DB01281 DB03403] DB01281|Abatacept CD80;CD86 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 25455:[DB01281 DB00685] DB01281|Abatacept CD80;CD86 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways 25456:[DB01281 DB02712] DB01281|Abatacept CD80;CD86 DB02712|Sorbinil AKR1B1 common genes common pathways 25457:[DB01281 DB08497] DB01281|Abatacept CD80;CD86 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0035556| intracellular signal transduction CASP3;CD80 25458:[DB01281 DB08155] DB01281|Abatacept CD80;CD86 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways 25459:[DB01281 DB07428] DB01281|Abatacept CD80;CD86 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 25460:[DB01281 DB04074] DB01281|Abatacept CD80;CD86 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 25461:[DB01281 DB03239] DB01281|Abatacept CD80;CD86 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways 25462:[DB01281 DB01102] DB01281|Abatacept CD80;CD86 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007165| signal transduction ADRB2;CD86;ADRB3;ADRB1 25463:[DB01281 DB04843] DB01281|Abatacept CD80;CD86 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CHRM3;CD86;CHRM1 25464:[DB01281 DB07067] DB01281|Abatacept CD80;CD86 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD86;DPP4;CD80 25465:[DB01281 DB05191] DB01281|Abatacept CD80;CD86 DB05191|Atl146e ADORA2A common genes common pathways GO:0007165| signal transduction ADORA2A;CD86 25466:[DB01281 DB01834] DB01281|Abatacept CD80;CD86 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways 25467:[DB01281 DB12458] DB01281|Abatacept CD80;CD86 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways GO:0007165| signal transduction GABRB3;CD86 25468:[DB01281 DB11703] DB01281|Abatacept CD80;CD86 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0002250| adaptive immune response CD86;BTK GO:0002376| immune system process BTK;CD86 GO:0035556| intracellular signal transduction CD80;BTK 25469:[DB01281 DB00655] DB01281|Abatacept CD80;CD86 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0007165| signal transduction ESR1;AR;ESR2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;AR;ESR1;CD80 GO:0008284| positive regulation of cell proliferation CD86;AR 25470:[DB01281 DB03268] DB01281|Abatacept CD80;CD86 DB03268|RU82197 SRC common genes common pathways GO:0007165| signal transduction SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction CD86;CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC 25471:[DB01281 DB00902] DB01281|Abatacept CD80;CD86 DB00902|Methdilazine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 25472:[DB01281 DB03593] DB01281|Abatacept CD80;CD86 DB03593|N7-Methyl-Guanosine-5'-Monophosphate DCPS common genes common pathways 25473:[DB01281 DB05087] DB01281|Abatacept CD80;CD86 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0007165| signal transduction CD86;GABRA5;GABRA6 25474:[DB01281 DB04562] DB01281|Abatacept CD80;CD86 DB04562|Tricarballylic Acid ACO2 common genes common pathways 25475:[DB01281 DB00886] DB01281|Abatacept CD80;CD86 DB00886|Omapatrilat ACE;MME common genes common pathways 25476:[DB01281 DB01626] DB01281|Abatacept CD80;CD86 DB01626|Pargyline MAOB;MAOA common genes common pathways 25477:[DB01281 DB14642] DB01281|Abatacept CD80;CD86 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0008284| positive regulation of cell proliferation AVPR2;CD86;AVPR1A GO:0007165| signal transduction AVPR1B;CD86;AVPR2;AVPR1A 25478:[DB01281 DB04865] DB01281|Abatacept CD80;CD86 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 25479:[DB01281 DB06536] DB01281|Abatacept CD80;CD86 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CD80;CD86;PPARG GO:0007165| signal transduction PPARG;CD86 25480:[DB01281 DB01081] DB01281|Abatacept CD80;CD86 DB01081|Diphenoxylate OPRM1;OPRD1 common genes common pathways GO:0007165| signal transduction OPRM1;OPRD1;CD86 GO:0006955| immune response OPRD1;CD86 25481:[DB01281 DB08760] DB01281|Abatacept CD80;CD86 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 GO:0007165| signal transduction PPARG;CD86 25482:[DB01281 DB04889] DB01281|Abatacept CD80;CD86 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD2;CD86 25483:[DB01281 DB00782] DB01281|Abatacept CD80;CD86 DB00782|Propantheline CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CD86;CHRM1 25484:[DB01281 DB00422] DB01281|Abatacept CD80;CD86 DB00422|Methylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways 25485:[DB01281 DB07642] DB01281|Abatacept CD80;CD86 DB07642|5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 25486:[DB01281 DB14508] DB01281|Abatacept CD80;CD86 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007165| signal transduction IMPA1;CD86;IMPA2 GO:0035556| intracellular signal transduction GSK3B;CD80 GO:0046854| phosphatidylinositol phosphorylation IMPA2;CD86;IMPA1;CD80 25487:[DB01281 DB04872] DB01281|Abatacept CD80;CD86 DB04872|Osanetant TACR3 common genes common pathways GO:0007165| signal transduction CD86;TACR3 25488:[DB01281 DB04187] DB01281|Abatacept CD80;CD86 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways 25489:[DB01281 DB01569] DB01281|Abatacept CD80;CD86 DB01569|Formebolone HSD11B2 common genes common pathways 25490:[DB01281 DB05434] DB01281|Abatacept CD80;CD86 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0007165| signal transduction FGF2;CXCL8;CD86 GO:0006955| immune response CXCL8;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;CD80;HGF GO:0035556| intracellular signal transduction CD80;CXCL8 GO:0046854| phosphatidylinositol phosphorylation FGF2;CD80;HGF;CD86 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade HGF;CD86;FGF2;CD80 GO:0008284| positive regulation of cell proliferation FGF2;VEGFA;CD86;HGF 25491:[DB01281 DB06731] DB01281|Abatacept CD80;CD86 DB06731|Seproxetine CYP3A5;CYP3A7;CYP2C9;CYP2C19 common genes common pathways 25492:[DB01281 DB06211] DB01281|Abatacept CD80;CD86 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways 25493:[DB01281 DB00517] DB01281|Abatacept CD80;CD86 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM3;CD86;CHRM1;CHRM2 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 25494:[DB01281 DB00131] DB01281|Abatacept CD80;CD86 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0016032| viral reproduction CD86;CREB1;CD80 GO:0035556| intracellular signal transduction CD80;ADCY1 GO:0007165| signal transduction PRKAB1;PRKAB2;HINT1;PDE4D;PDE4B;CD86;PRKAA1;ADCY1;CREB1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CREB1;CD86 GO:0008284| positive regulation of cell proliferation CD86;PRKAA1 25495:[DB01281 DB00594] DB01281|Abatacept CD80;CD86 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0007165| signal transduction ASIC1;PLAU;CD86 25496:[DB01281 DB06288] DB01281|Abatacept CD80;CD86 DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation DRD3;CD86;HTR2A GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0046718| entry of virus into host cell HTR2A;CD80;CD86 GO:0007165| signal transduction HTR2A;CD86;HTR7;DRD2;DRD3 25497:[DB01281 DB00569] DB01281|Abatacept CD80;CD86 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 25498:[DB01281 DB11358] DB01281|Abatacept CD80;CD86 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways 25499:[DB01281 DB09205] DB01281|Abatacept CD80;CD86 DB09205|Moxisylyte ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;BCHE common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;CD86;ADRA1D GO:0007165| signal transduction ADRA1B;ADRA2C;ADRA2B;ADRA2A;CD86;ADRA1A;ADRA1D GO:0035556| intracellular signal transduction ADRA1A;ADRA1B;CD80 25500:[DB01281 DB03059] DB01281|Abatacept CD80;CD86 DB03059|Acetoacetyl-CoA HADH;ACADS;ECHS1 common genes common pathways 25501:[DB01281 DB04066] DB01281|Abatacept CD80;CD86 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways 25502:[DB01281 DB09282] DB01281|Abatacept CD80;CD86 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0007165| signal transduction GUCY1A2;PDE5A;CD86 GO:0035556| intracellular signal transduction GUCY1A2;CD80 25503:[DB01281 DB00630] DB01281|Abatacept CD80;CD86 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0016032| viral reproduction CD86;FDPS;CD80 25504:[DB01281 DB00237] DB01281|Abatacept CD80;CD86 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 GO:0007165| signal transduction CD86;GABRA5;GABRD;GABRP;CHRNA4;GRIA2;GABRB3;CHRNA7;GABRE;GABRB1;GABRQ;GABRA6 25505:[DB01281 DB06098] DB01281|Abatacept CD80;CD86 DB06098|PRLX 93936 VDAC2;VDAC3 common genes common pathways 25506:[DB01281 DB08326] DB01281|Abatacept CD80;CD86 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways 25507:[DB01281 DB08846] DB01281|Abatacept CD80;CD86 DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes common pathways GO:0007165| signal transduction PRKCB;CSNK2A1;CD86 GO:0035556| intracellular signal transduction PRKCB;CD80;PRKCA;SYK GO:0016032| viral reproduction CD80;CD86;SYK GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SYK GO:0002376| immune system process SYK;CD86;PRKCB GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process SYK;CD80 GO:0002250| adaptive immune response PRKCB;SYK;CD86 25508:[DB01281 DB03349] DB01281|Abatacept CD80;CD86 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways GO:0007165| signal transduction HINT1;CD86;PDE4B 25509:[DB01281 DB02872] DB01281|Abatacept CD80;CD86 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways GO:0016032| viral reproduction CD86;MDM2;CD80 GO:0008284| positive regulation of cell proliferation MDM2;CD86 25510:[DB01281 DB08822] DB01281|Abatacept CD80;CD86 DB08822|Azilsartan medoxomil AGTR1 common genes common pathways GO:0007165| signal transduction AGTR1;CD86 25511:[DB01281 DB02837] DB01281|Abatacept CD80;CD86 DB02837|O4-Sulfonylgalactose MBL2 common genes common pathways GO:0002376| immune system process CD86;MBL2 25512:[DB01281 DB05418] DB01281|Abatacept CD80;CD86 DB05418|GW 597599 TACR1 common genes common pathways GO:0007165| signal transduction CD86;TACR1 25513:[DB01281 DB01080] DB01281|Abatacept CD80;CD86 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0007165| signal transduction GABBR1;CD86 25514:[DB01281 DB05218] DB01281|Abatacept CD80;CD86 DB05218|PN0621 TNF common genes common pathways GO:0006955| immune response CD86;TNF GO:0045893| positive regulation of transcription, DNA-dependent TNF;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;CD86;CD80 25515:[DB01281 DB07976] DB01281|Abatacept CD80;CD86 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways 25516:[DB01281 DB03791] DB01281|Abatacept CD80;CD86 DB03791|(3-{3-[[2-Chloro-3-(Trifluoromethyl)Benzyl](2,2-Diphenylethyl)Amino]Propoxy}Phenyl)Acetic Acid NR1H2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;NR1H2 25517:[DB01281 DB02499] DB01281|Abatacept CD80;CD86 DB02499|Dinor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0002376| immune system process ARG1;CD86 GO:0002250| adaptive immune response CD86;ARG1 25518:[DB01281 DB02109] DB01281|Abatacept CD80;CD86 DB02109|Hadacidin purA;ADSSL1 common genes common pathways GO:0002376| immune system process ADSSL1;CD86 25519:[DB01281 DB03415] DB01281|Abatacept CD80;CD86 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways 25520:[DB01281 DB06999] DB01281|Abatacept CD80;CD86 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways GO:0035556| intracellular signal transduction BRAF;CD80 GO:0007165| signal transduction CD86;BRAF 25521:[DB01281 DB07435] DB01281|Abatacept CD80;CD86 DB07435|1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE POLK;polA common genes common pathways 25522:[DB01281 DB00405] DB01281|Abatacept CD80;CD86 DB00405|Dexbrompheniramine HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 25523:[DB01281 DB04883] DB01281|Abatacept CD80;CD86 DB04883|Darusentan EDNRA common genes common pathways GO:0007165| signal transduction CD86;EDNRA 25524:[DB01281 DB00878] DB01281|Abatacept CD80;CD86 DB00878|Chlorhexidine HNMT;cat common genes common pathways 25525:[DB01281 DB09265] DB01281|Abatacept CD80;CD86 DB09265|Lixisenatide GLP1R common genes common pathways GO:0007165| signal transduction GLP1R;CD86 25526:[DB01281 DB07621] DB01281|Abatacept CD80;CD86 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways 25527:[DB01281 DB11429] DB01281|Abatacept CD80;CD86 DB11429|Mibolerone AR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR GO:0007165| signal transduction CD86;AR 25528:[DB01281 DB05466] DB01281|Abatacept CD80;CD86 DB05466|R673 TACR1 common genes common pathways GO:0007165| signal transduction TACR1;CD86 25529:[DB01281 DB05752] DB01281|Abatacept CD80;CD86 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;CHRM5;CHRM3;CD86;CHRM4 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 25530:[DB01281 DB07804] DB01281|Abatacept CD80;CD86 DB07804|5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 25531:[DB01281 DB04805] DB01281|Abatacept CD80;CD86 DB04805|Virginiamycin S1 RPL37 common genes common pathways 25532:[DB01281 DB06460] DB01281|Abatacept CD80;CD86 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways GO:0007165| signal transduction EDNRA;EDNRB;CD86 GO:0008284| positive regulation of cell proliferation EDNRB;CD86 25533:[DB01281 DB01019] DB01281|Abatacept CD80;CD86 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CHRM3;CD86;CHRM4;CHRM1;CHRM2 25534:[DB01281 DB13800] DB01281|Abatacept CD80;CD86 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways 25535:[DB01281 DB04527] DB01281|Abatacept CD80;CD86 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways GO:0002376| immune system process MASP2;CD86 25536:[DB01281 DB08491] DB01281|Abatacept CD80;CD86 DB08491|N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE MMP1 common genes common pathways GO:0016032| viral reproduction CD86;CD80;MMP1 25537:[DB01281 DB08613] DB01281|Abatacept CD80;CD86 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0008284| positive regulation of cell proliferation HDAC4;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;HDAC4;CD80 25538:[DB01281 DB01496] DB01281|Abatacept CD80;CD86 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GABRA5;CD86;GABRA6;CHRNA4;GRIA2;CHRNA7 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 25539:[DB01281 DB05194] DB01281|Abatacept CD80;CD86 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways GO:0006955| immune response CSF2;CD86 GO:0008284| positive regulation of cell proliferation CSF2;CD86 25540:[DB01281 DB11699] DB01281|Abatacept CD80;CD86 DB11699|Tropisetron HTR3A common genes common pathways GO:0007165| signal transduction CD86;HTR3A 25541:[DB01281 DB07384] DB01281|Abatacept CD80;CD86 DB07384|1-ACETYL-2-CARBOXYPIPERIDINE ATP5B common genes common pathways 25542:[DB01281 DB13994] DB01281|Abatacept CD80;CD86 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 25543:[DB01281 DB07712] DB01281|Abatacept CD80;CD86 DB07712|3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 GO:0007165| signal transduction ESR1;CD86 25544:[DB01281 DB07798] DB01281|Abatacept CD80;CD86 DB07798|(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 25545:[DB01281 DB02670] DB01281|Abatacept CD80;CD86 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;SMARCA5;CD80 25546:[DB01281 DB02755] DB01281|Abatacept CD80;CD86 DB02755|1-3 Sugar Ring of Pentamannosyl 6-Phosphate M6PR common genes common pathways GO:0007165| signal transduction CD86;M6PR 25547:[DB01281 DB00565] DB01281|Abatacept CD80;CD86 DB00565|Cisatracurium CHRNA2 common genes common pathways GO:0007165| signal transduction CD86;CHRNA2 25548:[DB01281 DB06925] DB01281|Abatacept CD80;CD86 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade LCK;CD86;CD80 GO:0031295| T cell costimulation CD80;CD86;LCK GO:0046854| phosphatidylinositol phosphorylation CD86;LCK;CD80 GO:0016032| viral reproduction LCK;CD86;CD80 25549:[DB01281 DB08502] DB01281|Abatacept CD80;CD86 DB08502|Capravirine CYP3A4 common genes common pathways 25550:[DB01281 DB05685] DB01281|Abatacept CD80;CD86 DB05685|FX06 CDH5 common genes common pathways 25551:[DB01281 DB00494] DB01281|Abatacept CD80;CD86 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways 25552:[DB01281 DB01548] DB01281|Abatacept CD80;CD86 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0007165| signal transduction CD86;TRIM13;OPRK1;OPRM1;OPRD1 GO:0006955| immune response CD86;OPRK1;OPRD1 25553:[DB01281 DB11256] DB01281|Abatacept CD80;CD86 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways 25554:[DB01281 DB11064] DB01281|Abatacept CD80;CD86 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0007165| signal transduction CD86;PGR;ESR1;AR GO:0045893| positive regulation of transcription, DNA-dependent CD86;AR;ESR1;CD80 GO:0008284| positive regulation of cell proliferation CD86;AR 25555:[DB01281 DB03152] DB01281|Abatacept CD80;CD86 DB03152|B-2-Octylglucoside polA;aqpZ;TGM3;aqpZ;petB;petA;RHO common genes common pathways GO:0007165| signal transduction RHO;CD86 25556:[DB01281 DB05044] DB01281|Abatacept CD80;CD86 DB05044|PSN357 PYGL common genes common pathways 25557:[DB01281 DB03926] DB01281|Abatacept CD80;CD86 DB03926|5-Alpha-Androstane-3-Beta,17-Alpha-Diol SHBG common genes common pathways 25558:[DB01281 DB07720] DB01281|Abatacept CD80;CD86 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 GO:0007165| signal transduction CD86;CHRNA3;CHRNB4;CHRNB2;CHRNA7;CHRNA4;CHRNA2;CHRFAM7A 25559:[DB01281 DB07694] DB01281|Abatacept CD80;CD86 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways 25560:[DB01281 DB05201] DB01281|Abatacept CD80;CD86 DB05201|V24343 CNR1 common genes common pathways GO:0007165| signal transduction CD86;CNR1 25561:[DB01281 DB05451] DB01281|Abatacept CD80;CD86 DB05451|P54 NFKB2;NFKB1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;CD80;CD86 GO:0007165| signal transduction CD86;NFKB2;NFKB1 25562:[DB01281 DB03566] DB01281|Abatacept CD80;CD86 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0007165| signal transduction TXNRD1;ADRB2;ADRB1;CD86 25563:[DB01281 DB09331] DB01281|Abatacept CD80;CD86 DB09331|Daratumumab CD38 common genes common pathways GO:0007165| signal transduction CD86;CD38 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD38;CD80 25564:[DB01281 DB01337] DB01281|Abatacept CD80;CD86 DB01337|Pancuronium CHRNA2;CHRM2;CHRM3;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0007165| signal transduction CHRNA2;CHRM2;CD86;CHRM3 25565:[DB01281 DB06111] DB01281|Abatacept CD80;CD86 DB06111|AB192 MPO common genes common pathways 25566:[DB01281 DB01977] DB01281|Abatacept CD80;CD86 DB01977|6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 25567:[DB01281 DB04915] DB01281|Abatacept CD80;CD86 DB04915|Idronoxil ENOX2 common genes common pathways 25568:[DB01281 DB04997] DB01281|Abatacept CD80;CD86 DB04997|ATL1102 ITGA4 common genes common pathways 25569:[DB01281 DB05091] DB01281|Abatacept CD80;CD86 DB05091|M0002 AVPR2 common genes common pathways GO:0008284| positive regulation of cell proliferation AVPR2;CD86 GO:0007165| signal transduction AVPR2;CD86 25570:[DB01281 DB00704] DB01281|Abatacept CD80;CD86 DB00704|Naltrexone OPRD1;OPRM1;OPRK1;SIGMAR1;UGT1A1 common genes common pathways GO:0006955| immune response OPRD1;CD86;OPRK1 GO:0007165| signal transduction OPRM1;OPRD1;OPRK1;CD86 25571:[DB01281 DB07334] DB01281|Abatacept CD80;CD86 DB07334|N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE KDR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;KDR GO:0016032| viral reproduction CD80;KDR;CD86 25572:[DB01281 DB08172] DB01281|Abatacept CD80;CD86 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways 25573:[DB01281 DB00790] DB01281|Abatacept CD80;CD86 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways 25574:[DB01281 DB01962] DB01281|Abatacept CD80;CD86 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways GO:0007165| signal transduction SRC;KIT;CD86 GO:0035556| intracellular signal transduction KIT;SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction CD86;HCK;SRC;CD80 GO:0002376| immune system process CD86;SRC;HCK GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;KIT;CD80 GO:0008284| positive regulation of cell proliferation CD86;KIT;HCK GO:0051897| positive regulation of protein kinase B signaling cascade SRC;KIT;CD80;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 25575:[DB01281 DB01835] DB01281|Abatacept CD80;CD86 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways 25576:[DB01281 DB03419] DB01281|Abatacept CD80;CD86 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0016032| viral reproduction CD80;UCKL1;CD86 25577:[DB01281 DB01296] DB01281|Abatacept CD80;CD86 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0008284| positive regulation of cell proliferation IFNG;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;CD86;CD80 GO:0002250| adaptive immune response IFNG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;TNF;CD86 GO:0007165| signal transduction CD86;NFKB2 GO:0006955| immune response TNF;CD86;IFNG 25578:[DB01281 DB12866] DB01281|Abatacept CD80;CD86 DB12866|Pradigastat SLC22A8 common genes common pathways 25579:[DB01281 DB02974] DB01281|Abatacept CD80;CD86 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways 25580:[DB01281 DB04674] DB01281|Abatacept CD80;CD86 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0007165| signal transduction CD86;EDNRA 25581:[DB01281 DB13150] DB01281|Abatacept CD80;CD86 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F3;CD80;CD86;F10 25582:[DB01281 DB04827] DB01281|Abatacept CD80;CD86 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways 25583:[DB01281 DB00521] DB01281|Abatacept CD80;CD86 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0007165| signal transduction ADRB2;CD86;ADRB1 25584:[DB01281 DB06842] DB01281|Abatacept CD80;CD86 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways GO:0007165| signal transduction CD86;PDE4D;PDE4A 25585:[DB01281 DB05419] DB01281|Abatacept CD80;CD86 DB05419|ADX-10061 CALY common genes common pathways 25586:[DB01281 DB07695] DB01281|Abatacept CD80;CD86 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways 25587:[DB01281 DB07851] DB01281|Abatacept CD80;CD86 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell DPP4;CD86;CD80 25588:[DB01281 DB06782] DB01281|Abatacept CD80;CD86 DB06782|Dimercaprol APP common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;APP 25589:[DB01281 DB00852] DB01281|Abatacept CD80;CD86 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0007165| signal transduction ADRB2;ADRA2A;CD86;ADRA1A;ADRB1;ATF6 GO:0035556| intracellular signal transduction NFATC1;CD80;ADRA1A GO:0016032| viral reproduction CD86;ATF7;CD80 GO:0006955| immune response TNF;CD86;IL2 GO:0002376| immune system process CD86;IL2 GO:0008284| positive regulation of cell proliferation CD86;IL2;ADRA2A;ATF3;JUN GO:0045893| positive regulation of transcription, DNA-dependent CD86;ATF5;TNF;FOS;NFATC1;JUN;CD80;ATF4 GO:0002250| adaptive immune response CD86;IL2 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 25590:[DB01281 DB03083] DB01281|Abatacept CD80;CD86 DB03083|IC261 CSNK1G2 common genes common pathways GO:0007165| signal transduction CD86;CSNK1G2 25591:[DB01281 DB07765] DB01281|Abatacept CD80;CD86 DB07765|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways 25592:[DB01281 DB02773] DB01281|Abatacept CD80;CD86 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways 25593:[DB01281 DB05022] DB01281|Abatacept CD80;CD86 DB05022|Amonafide TOP2A;TOP2B common genes common pathways 25594:[DB01281 DB06972] DB01281|Abatacept CD80;CD86 DB06972|7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile ITGAL common genes common pathways GO:0007165| signal transduction ITGAL;CD86 25595:[DB01281 DB00192] DB01281|Abatacept CD80;CD86 DB00192|Indecainide SCN5A common genes common pathways 25596:[DB01281 DB00534] DB01281|Abatacept CD80;CD86 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways 25597:[DB01281 DB02215] DB01281|Abatacept CD80;CD86 DB02215|Furoyl-Leucine ADAM28 common genes common pathways 25598:[DB01281 DB08299] DB01281|Abatacept CD80;CD86 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways GO:0007165| signal transduction PDE4A;PDE4D;CD86;PDE4B 25599:[DB01281 DB00229] DB01281|Abatacept CD80;CD86 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways 25600:[DB01281 DB05210] DB01281|Abatacept CD80;CD86 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0016032| viral reproduction PIK3R1;CD86;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;CD80 GO:0007165| signal transduction MTOR;PIK3R2;CD86;PIK3R1 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;PIK3R1;MTOR;PIK3R2;CD80 GO:0046854| phosphatidylinositol phosphorylation PIK3R1;CD86;PIK3R2;CD80 GO:0031295| T cell costimulation CD86;PIK3R1;CD80 GO:0002376| immune system process CD86;PRKDC 25601:[DB01281 DB00963] DB01281|Abatacept CD80;CD86 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 25602:[DB01281 DB07872] DB01281|Abatacept CD80;CD86 DB07872|5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 25603:[DB01281 DB00574] DB01281|Abatacept CD80;CD86 DB00574|Fenfluramine SLC6A4;HTR2B;HTR2C;HTR2A;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;HTR2B;CD86 GO:0007165| signal transduction HTR2A;CD86;HTR2C;HTR2B GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A 25604:[DB01281 DB01819] DB01281|Abatacept CD80;CD86 DB01819|Phosphoenolpyruvate aroG;kdsA;ENO3;PCK1;kdsA;SLCO2A1 common genes common pathways 25605:[DB01281 DB05305] DB01281|Abatacept CD80;CD86 DB05305|Cintredekin Besudotox IL13 common genes common pathways GO:0006955| immune response IL13;CD86 25606:[DB01281 DB06138] DB01281|Abatacept CD80;CD86 DB06138|IRL-1620 EDNRB common genes common pathways GO:0007165| signal transduction CD86;EDNRB GO:0008284| positive regulation of cell proliferation EDNRB;CD86 25607:[DB01281 DB07963] DB01281|Abatacept CD80;CD86 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways 25608:[DB01281 DB11491] DB01281|Abatacept CD80;CD86 DB11491|Sarafloxacin CYP1A2 common genes common pathways 25609:[DB01281 DB02635] DB01281|Abatacept CD80;CD86 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways 25610:[DB01281 DB06751] DB01281|Abatacept CD80;CD86 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0007165| signal transduction CD86;PDE4A 25611:[DB01281 DB04926] DB01281|Abatacept CD80;CD86 DB04926|Neramexane GRIN3A common genes common pathways 25612:[DB01281 DB07132] DB01281|Abatacept CD80;CD86 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways GO:0031295| T cell costimulation CD86;PDPK1;CD80 GO:0035556| intracellular signal transduction PDPK1;CD80 25613:[DB01281 DB01650] DB01281|Abatacept CD80;CD86 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways 25614:[DB01281 DB03928] DB01281|Abatacept CD80;CD86 DB03928|Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol CTH common genes common pathways 25615:[DB01281 DB07006] DB01281|Abatacept CD80;CD86 DB07006|9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE WEE1 common genes common pathways 25616:[DB01281 DB04392] DB01281|Abatacept CD80;CD86 DB04392|Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] NQO1;azoR common genes common pathways 25617:[DB01281 DB03611] DB01281|Abatacept CD80;CD86 DB03611|L-2-amino-4-methoxy-cis-but-3-enoic acid MAT1A common genes common pathways 25618:[DB01281 DB00150] DB01281|Abatacept CD80;CD86 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0002376| immune system process IDO1;CD86 25619:[DB01281 DB02825] DB01281|Abatacept CD80;CD86 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways 25620:[DB01281 DB02854] DB01281|Abatacept CD80;CD86 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0002376| immune system process CD86;IGHG2 GO:0002250| adaptive immune response CD86;IGHG2 25621:[DB01281 DB06534] DB01281|Abatacept CD80;CD86 DB06534|Thrombopoietin MPL common genes common pathways 25622:[DB01281 DB05166] DB01281|Abatacept CD80;CD86 DB05166|APD668 GPR119 common genes common pathways GO:0007165| signal transduction CD86;GPR119 25623:[DB01281 DB12035] DB01281|Abatacept CD80;CD86 DB12035|Sarecycline ABCB1 common genes common pathways 25624:[DB01281 DB11577] DB01281|Abatacept CD80;CD86 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A GO:0007165| signal transduction ADRA2C;ADRA2B;ADRA1B;ADRA1D;ADRA1A;ADRA2A;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AHR;CD86 GO:0008284| positive regulation of cell proliferation CD86;ADRA2A;ADRA1D 25625:[DB01281 DB01288] DB01281|Abatacept CD80;CD86 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0007165| signal transduction ADRB1;ADRB3;CD86;ADRB2 25626:[DB01281 DB04695] DB01281|Abatacept CD80;CD86 DB04695|Farnesyl thiopyrophosphate ispU;GGPS1;MVK common genes common pathways 25627:[DB01281 DB12077] DB01281|Abatacept CD80;CD86 DB12077|Urelumab TNFRSF9 common genes common pathways GO:0006955| immune response CD86;TNFRSF9 25628:[DB01281 DB06274] DB01281|Abatacept CD80;CD86 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0006955| immune response OPRK1;CD86;OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;OPRK1;CD86 25629:[DB01281 DB11431] DB01281|Abatacept CD80;CD86 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways 25630:[DB01281 DB05042] DB01281|Abatacept CD80;CD86 DB05042|SGS518 HTR6 common genes common pathways GO:0007165| signal transduction HTR6;CD86 25631:[DB01281 DB05688] DB01281|Abatacept CD80;CD86 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways 25632:[DB01281 DB04958] DB01281|Abatacept CD80;CD86 DB04958|Epratuzumab CD22 common genes common pathways 25633:[DB01281 DB04166] DB01281|Abatacept CD80;CD86 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways 25634:[DB01281 DB00047] DB01281|Abatacept CD80;CD86 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;INSR;IGF1R GO:0051897| positive regulation of protein kinase B signaling cascade INSR;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent INSR;CD86;CD80 GO:0007165| signal transduction CD86;IGF1R GO:0035556| intracellular signal transduction INSR;CD80 GO:0006955| immune response IGF1R;CD86 25635:[DB01281 DB12890] DB01281|Abatacept CD80;CD86 DB12890|Dihydrexidine DRD1 common genes common pathways GO:0007165| signal transduction DRD1;CD86 25636:[DB01281 DB00130] DB01281|Abatacept CD80;CD86 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0046718| entry of virus into host cell CD86;CD80;SLC1A5 GO:0016032| viral reproduction CD80;SLC1A5;CD86 GO:0002376| immune system process CTPS1;CD86 25637:[DB01281 DB06579] DB01281|Abatacept CD80;CD86 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0007165| signal transduction GABRA5;CD86;GABRA6 25638:[DB01281 DB00459] DB01281|Abatacept CD80;CD86 DB00459|Acitretin RXRA;RARA;RARB;RARG;RXRB;RXRG;RBP1;CYP26A1;ALB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;RXRA;RARA;CD80 GO:0008284| positive regulation of cell proliferation CD86;RARB;RARG;RARA GO:0045630| positive regulation of T-helper 2 cell differentiation CD86;RARA GO:0016032| viral reproduction CD80;RXRA;CD86 GO:0007165| signal transduction RARA;CD86;RARB 25639:[DB01281 DB14069] DB01281|Abatacept CD80;CD86 DB14069|ONT-093 ABCB1 common genes common pathways 25640:[DB01281 DB07427] DB01281|Abatacept CD80;CD86 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways 25641:[DB01281 DB03525] DB01281|Abatacept CD80;CD86 DB03525|RU79073 SRC common genes common pathways GO:0007165| signal transduction SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction SRC;CD80;CD86 GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0002376| immune system process CD86;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 25642:[DB01281 DB00117] DB01281|Abatacept CD80;CD86 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways 25643:[DB01281 DB03976] DB01281|Abatacept CD80;CD86 DB03976|Phosphorylisopropane PRSS1;PRSS2;CTRB1;BCHE common genes common pathways 25644:[DB01281 DB04472] DB01281|Abatacept CD80;CD86 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways GO:0002376| immune system process LGALS9;CD86 25645:[DB01281 DB06749] DB01281|Abatacept CD80;CD86 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways 25646:[DB01281 DB06714] DB01281|Abatacept CD80;CD86 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways GO:0007165| signal transduction TAAR1;CD86 25647:[DB01281 DB05034] DB01281|Abatacept CD80;CD86 DB05034|Ularitide NPR1 common genes common pathways GO:0035556| intracellular signal transduction NPR1;CD80 25648:[DB01281 DB08210] DB01281|Abatacept CD80;CD86 DB08210|2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE GCK common genes common pathways 25649:[DB01281 DB01463] DB01281|Abatacept CD80;CD86 DB01463|Fencamfamine SLC6A3 common genes common pathways 25650:[DB01281 DB04929] DB01281|Abatacept CD80;CD86 DB04929|DG031 ALOX5AP common genes common pathways 25651:[DB01281 DB04602] DB01281|Abatacept CD80;CD86 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 25652:[DB01281 DB01561] DB01281|Abatacept CD80;CD86 DB01561|Androstanedione HSD17B1 common genes common pathways 25653:[DB01281 DB08597] DB01281|Abatacept CD80;CD86 DB08597|6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine ACVR1;FKBP1A common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;ACVR1;CD86 25654:[DB01281 DB07605] DB01281|Abatacept CD80;CD86 DB07605|2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 25655:[DB01281 DB08733] DB01281|Abatacept CD80;CD86 DB08733|(2R,3R)-N^1^-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N^4^-HYDROXY-2-(2-METHYLPROPYL)-3-{[(1,3-THIAZOL-2-YLCARBONYL)AMINO]METHYL}BUTANEDIAMIDE ADAM28 common genes common pathways 25656:[DB01281 DB03917] DB01281|Abatacept CD80;CD86 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways 25657:[DB01281 DB05290] DB01281|Abatacept CD80;CD86 DB05290|SPP 301 EDNRA common genes common pathways GO:0007165| signal transduction CD86;EDNRA 25658:[DB01281 DB09142] DB01281|Abatacept CD80;CD86 DB09142|Sincalide SLCO1B3 common genes common pathways 25659:[DB01281 DB06342] DB01281|Abatacept CD80;CD86 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD19;CD80 GO:0046854| phosphatidylinositol phosphorylation CD86;CD19;CD80 25660:[DB01281 DB04299] DB01281|Abatacept CD80;CD86 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0016032| viral reproduction CD80;TPR;CD86 25661:[DB01281 DB00529] DB01281|Abatacept CD80;CD86 DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways 25662:[DB01281 DB03807] DB01281|Abatacept CD80;CD86 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways GO:0007165| signal transduction PDE4B;CD86 25663:[DB01281 DB07194] DB01281|Abatacept CD80;CD86 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SYK;CD80 GO:0016032| viral reproduction CD80;CD86;SYK GO:0035556| intracellular signal transduction SYK;CD80 GO:0002250| adaptive immune response SYK;CD86 GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process SYK;CD80 GO:0002376| immune system process SYK;CD86 25664:[DB01281 DB09108] DB01281|Abatacept CD80;CD86 DB09108|Simoctocog Alfa VWF common genes common pathways 25665:[DB01281 DB07423] DB01281|Abatacept CD80;CD86 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 GO:0007165| signal transduction AR;CD86 25666:[DB01281 DB00537] DB01281|Abatacept CD80;CD86 DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways 25667:[DB01281 DB02323] DB01281|Abatacept CD80;CD86 DB02323|EM-1745 HSD17B1 common genes common pathways 25668:[DB01281 DB00713] DB01281|Abatacept CD80;CD86 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways 25669:[DB01281 DB02542] DB01281|Abatacept CD80;CD86 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways 25670:[DB01281 DB01047] DB01281|Abatacept CD80;CD86 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;SMO GO:0045893| positive regulation of transcription, DNA-dependent SMO;CD80;CD86 GO:0007165| signal transduction CD86;NR3C1;SMO 25671:[DB01281 DB04464] DB01281|Abatacept CD80;CD86 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0002376| immune system process HLA-B;CD86;B2M GO:0008284| positive regulation of cell proliferation S100B;CD86 GO:0016032| viral reproduction CD80;HLA-B;CD86 GO:0006955| immune response HLA-B;CD86;B2M 25672:[DB01281 DB02796] DB01281|Abatacept CD80;CD86 DB02796|9-Deazainosine PNP common genes common pathways GO:0006955| immune response CD86;PNP 25673:[DB01281 DB02162] DB01281|Abatacept CD80;CD86 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways GO:0007165| signal transduction HINT1;CD86 25674:[DB01281 DB08374] DB01281|Abatacept CD80;CD86 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways 25675:[DB01281 DB04260] DB01281|Abatacept CD80;CD86 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways GO:0006955| immune response PNP;CD86 25676:[DB01281 DB08357] DB01281|Abatacept CD80;CD86 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways 25677:[DB01281 DB00010] DB01281|Abatacept CD80;CD86 DB00010|Sermorelin GHRHR common genes common pathways GO:0008284| positive regulation of cell proliferation GHRHR;CD86 GO:0007165| signal transduction GHRHR;CD86 25678:[DB01281 DB08362] DB01281|Abatacept CD80;CD86 DB08362|N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 GO:0007165| signal transduction CSNK2A1;CD86 25679:[DB01281 DB08900] DB01281|Abatacept CD80;CD86 DB08900|Teduglutide GLP2R common genes common pathways GO:0008284| positive regulation of cell proliferation GLP2R;CD86 GO:0007165| signal transduction GLP2R;CD86 25680:[DB01281 DB13167] DB01281|Abatacept CD80;CD86 DB13167|Alclofenac PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 25681:[DB01281 DB05941] DB01281|Abatacept CD80;CD86 DB05941|Leronlimab CCR5 common genes common pathways GO:0016032| viral reproduction CD80;CD86;CCR5 GO:0006955| immune response CCR5;CD86 GO:0007165| signal transduction CCR5;CD86 25682:[DB01281 DB13929] DB01281|Abatacept CD80;CD86 DB13929|Relcovaptan OXTR;AVPR1A common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AVPR1A GO:0007165| signal transduction AVPR1A;OXTR;CD86 25683:[DB01281 DB03589] DB01281|Abatacept CD80;CD86 DB03589|Alpha-Ketomalonic Acid ME2 common genes common pathways 25684:[DB01281 DB00036] DB01281|Abatacept CD80;CD86 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F3;CD86;F7;F10 25685:[DB01281 DB07567] DB01281|Abatacept CD80;CD86 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 25686:[DB01281 DB03660] DB01281|Abatacept CD80;CD86 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 25687:[DB01281 DB06916] DB01281|Abatacept CD80;CD86 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways 25688:[DB01281 DB12271] DB01281|Abatacept CD80;CD86 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways 25689:[DB01281 DB03060] DB01281|Abatacept CD80;CD86 DB03060|Sri-9662 DHFR common genes common pathways 25690:[DB01281 DB01307] DB01281|Abatacept CD80;CD86 DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0035556| intracellular signal transduction CD80;INSR GO:0008284| positive regulation of cell proliferation CD86;INSR GO:0045893| positive regulation of transcription, DNA-dependent INSR;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;CD86;CD80 25691:[DB01281 DB02093] DB01281|Abatacept CD80;CD86 DB02093|5-Phospho-D-Arabinohydroxamic Acid GPI common genes common pathways 25692:[DB01281 DB01571] DB01281|Abatacept CD80;CD86 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response OPRD1;OPRK1;CD86 GO:0007165| signal transduction CD86;OPRK1;OPRM1;OPRD1 25693:[DB01281 DB01408] DB01281|Abatacept CD80;CD86 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0007165| signal transduction ADRB2;CD86 25694:[DB01281 DB00652] DB01281|Abatacept CD80;CD86 DB00652|Pentazocine OPRM1;OPRK1;SIGMAR1 common genes common pathways GO:0006955| immune response CD86;OPRK1 GO:0007165| signal transduction OPRM1;CD86;OPRK1 25695:[DB01281 DB02689] DB01281|Abatacept CD80;CD86 DB02689|S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine ARG1 common genes common pathways GO:0002376| immune system process CD86;ARG1 GO:0002250| adaptive immune response ARG1;CD86 25696:[DB01281 DB00340] DB01281|Abatacept CD80;CD86 DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM5;CHRM1;CHRM2;CHRM4;CD86;CHRM3 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 25697:[DB01281 DB08737] DB01281|Abatacept CD80;CD86 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 25698:[DB01281 DB04343] DB01281|Abatacept CD80;CD86 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways 25699:[DB01281 DB04478] DB01281|Abatacept CD80;CD86 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways 25700:[DB01281 DB00324] DB01281|Abatacept CD80;CD86 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 25701:[DB01281 DB01955] DB01281|Abatacept CD80;CD86 DB01955|1,4-Butanediol MAN1B1;PLA2G2A;PLA2G2E common genes common pathways 25702:[DB01281 DB07380] DB01281|Abatacept CD80;CD86 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 25703:[DB01281 DB02067] DB01281|Abatacept CD80;CD86 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways 25704:[DB01281 DB03341] DB01281|Abatacept CD80;CD86 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways 25705:[DB01281 DB02477] DB01281|Abatacept CD80;CD86 DB02477|[Cyclohexylethyl]-[[[[4-[2-Methyl-1-Imidazolyl-Butyl]Phenyl]Acetyl]-Seryl]-Lysinyl]-Amine NMT1 common genes common pathways 25706:[DB01281 DB05072] DB01281|Abatacept CD80;CD86 DB05072|AV608 TACR1 common genes common pathways GO:0007165| signal transduction TACR1;CD86 25707:[DB01281 DB13878] DB01281|Abatacept CD80;CD86 DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 25708:[DB01281 DB02648] DB01281|Abatacept CD80;CD86 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways 25709:[DB01281 DB06406] DB01281|Abatacept CD80;CD86 DB06406|Idraparinux F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;CD86;CD80 25710:[DB01281 DB02583] DB01281|Abatacept CD80;CD86 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways 25711:[DB01281 DB01727] DB01281|Abatacept CD80;CD86 DB01727|Isocitric Acid icd;icd;ACO2;IDH2;IDH1 common genes common pathways 25712:[DB01281 DB04230] DB01281|Abatacept CD80;CD86 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 25713:[DB01281 DB02078] DB01281|Abatacept CD80;CD86 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways GO:0031295| T cell costimulation CD80;FYN;CD86 GO:0002376| immune system process FYN;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;FYN;CD86 GO:0002250| adaptive immune response FYN;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;FYN;CD80 GO:0035556| intracellular signal transduction FYN;CD80 GO:0016032| viral reproduction CD80;FYN;CD86 25714:[DB01281 DB01942] DB01281|Abatacept CD80;CD86 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;NOS1;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;FGF1;CD86 GO:0008284| positive regulation of cell proliferation CD86;FGF1 GO:0046854| phosphatidylinositol phosphorylation CD80;FGF1;CD86 GO:0016032| viral reproduction CTBP1;CD80;CD86 GO:0035556| intracellular signal transduction HMOX1;CD80 GO:0007165| signal transduction CD86;FGF1 25715:[DB01281 DB08447] DB01281|Abatacept CD80;CD86 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways 25716:[DB01281 DB08258] DB01281|Abatacept CD80;CD86 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways 25717:[DB01281 DB01007] DB01281|Abatacept CD80;CD86 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways 25718:[DB01281 DB06711] DB01281|Abatacept CD80;CD86 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways GO:0035556| intracellular signal transduction CD80;ADRA1A GO:0007165| signal transduction ADRA1A;ADRA2A;CD86 GO:0008284| positive regulation of cell proliferation CD86;ADRA2A 25719:[DB01281 DB00513] DB01281|Abatacept CD80;CD86 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways 25720:[DB01281 DB03964] DB01281|Abatacept CD80;CD86 DB03964|4-Hydroxy-Aconitate Ion ACO2 common genes common pathways 25721:[DB01281 DB09481] DB01281|Abatacept CD80;CD86 DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways 25722:[DB01281 DB07666] DB01281|Abatacept CD80;CD86 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;CD86;DPP4 25723:[DB01281 DB04237] DB01281|Abatacept CD80;CD86 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways 25724:[DB01281 DB03115] DB01281|Abatacept CD80;CD86 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways GO:0007165| signal transduction CD86;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;MAP2K1;CD80 25725:[DB01281 DB03924] DB01281|Abatacept CD80;CD86 DB03924|5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone CSNK2A1 common genes common pathways GO:0007165| signal transduction CD86;CSNK2A1 GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 25726:[DB01281 DB13746] DB01281|Abatacept CD80;CD86 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;CACNA1I 25727:[DB01281 DB03802] DB01281|Abatacept CD80;CD86 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 25728:[DB01281 DB04365] DB01281|Abatacept CD80;CD86 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CHRM3;CD86;CHRM1 25729:[DB01281 DB01593] DB01281|Abatacept CD80;CD86 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;TP53;INS;IL3;AGT;CD80;VTN GO:0006955| immune response IL3;C3;C1QC;IGHA1;C8A;IGLV3-21;VTN;CD86;JCHAIN;IGKV1-17;C1R;C8B GO:0016032| viral reproduction APOA2;TP53;MDM2;IDE;HDAC1;TP73;CFH;CD86;CD80;SIVA1 GO:0007165| signal transduction BDKRB1;PDIA3;IGFALS;CD86;FGA;ESR1;C3;JUP GO:0046718| entry of virus into host cell IDE;CD86;CD80;SIVA1 GO:0051897| positive regulation of protein kinase B signaling cascade INS;CD80;CD86;APP GO:0002250| adaptive immune response IGLV3-21;IGHA1;FGA;JCHAIN;CD86;IGKV1-17;IGHM GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;AGT;MT3;TP53;HDAC4;HDAC1;TP73;CD86 GO:0008284| positive regulation of cell proliferation KRT6A;AGT;IL3;INS;MDM2;HDAC1;FN1;HDAC4;F2;CD86 GO:0002376| immune system process CLU;C1QB;C8B;C1R;IGHM;FCN3;CFH;FGA;IGKV1-17;CFB;CD86;IGLV3-21;S100A8;C4BPB;C8A;S100A9;IGHA1;C1S;C5;C1QC;C3;CFI;C4B;C8G;C4BPA;PGLYRP2 25730:[DB01281 DB13893] DB01281|Abatacept CD80;CD86 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways GO:0006955| immune response CD86;ENPP1 25731:[DB01281 DB08387] DB01281|Abatacept CD80;CD86 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0007165| signal transduction CD86;PDE10A 25732:[DB01281 DB00607] DB01281|Abatacept CD80;CD86 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways 25733:[DB01281 DB05932] DB01281|Abatacept CD80;CD86 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;CD80 GO:0008284| positive regulation of cell proliferation CD86;FLT4;FLT1;VEGFA 25734:[DB01281 DB06786] DB01281|Abatacept CD80;CD86 DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;SMO GO:0008284| positive regulation of cell proliferation SMO;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;SMO 25735:[DB01281 DB07513] DB01281|Abatacept CD80;CD86 DB07513|7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE MAOB common genes common pathways 25736:[DB01281 DB13141] DB01281|Abatacept CD80;CD86 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 25737:[DB01281 DB05096] DB01281|Abatacept CD80;CD86 DB05096|LY2140023 GRM2;GRM3 common genes common pathways GO:0007165| signal transduction GRM2;CD86;GRM3 25738:[DB01281 DB01275] DB01281|Abatacept CD80;CD86 DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways 25739:[DB01281 DB05343] DB01281|Abatacept CD80;CD86 DB05343|Arundic acid S100B common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;S100B 25740:[DB01281 DB00134] DB01281|Abatacept CD80;CD86 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0002376| immune system process CD86;MSRB1 25741:[DB01281 DB04973] DB01281|Abatacept CD80;CD86 DB04973|LErafAON RAF1 common genes common pathways GO:0035556| intracellular signal transduction CD80;RAF1 GO:0007165| signal transduction CD86;RAF1 25742:[DB01281 DB05895] DB01281|Abatacept CD80;CD86 DB05895|HGS-TR2J TNFRSF10B common genes common pathways GO:0006955| immune response TNFRSF10B;CD86 GO:0007165| signal transduction TNFRSF10B;CD86 25743:[DB01281 DB02943] DB01281|Abatacept CD80;CD86 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways 25744:[DB01281 DB01327] DB01281|Abatacept CD80;CD86 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006955| immune response IL2;CD86;IL15 GO:0007165| signal transduction CD86;IL15 GO:0002250| adaptive immune response IL2;CD86 GO:0008284| positive regulation of cell proliferation IL15;CD86;IL2 GO:0002376| immune system process IL2;CD86 25745:[DB01281 DB07280] DB01281|Abatacept CD80;CD86 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 25746:[DB01281 DB03182] DB01281|Abatacept CD80;CD86 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 25747:[DB01281 DB02021] DB01281|Abatacept CD80;CD86 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways 25748:[DB01281 DB02164] DB01281|Abatacept CD80;CD86 DB02164|N-Sulfo-Flavin Mononucleotide HAO1 common genes common pathways 25749:[DB01281 DB04616] DB01281|Abatacept CD80;CD86 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways 25750:[DB01281 DB03879] DB01281|Abatacept CD80;CD86 DB03879|alpha-L-methyl-fucose MBL2 common genes common pathways GO:0002376| immune system process CD86;MBL2 25751:[DB01281 DB13923] DB01281|Abatacept CD80;CD86 DB13923|Emicizumab F9;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 25752:[DB01281 DB14061] DB01281|Abatacept CD80;CD86 DB14061|Hycanthone ABCB1 common genes common pathways 25753:[DB01281 DB05771] DB01281|Abatacept CD80;CD86 DB05771|LLL-3348 IL10 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;IL10 GO:0006955| immune response IL10;CD86 25754:[DB01281 DB07470] DB01281|Abatacept CD80;CD86 DB07470|(3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 25755:[DB01281 DB06458] DB01281|Abatacept CD80;CD86 DB06458|Remacemide CYP3A4 common genes common pathways 25756:[DB01281 DB12831] DB01281|Abatacept CD80;CD86 DB12831|Gabexate KLKB1;F2;PLG;PRSS1;C1S;C1R common genes common pathways GO:0002376| immune system process C1S;C1R;CD86 GO:0008284| positive regulation of cell proliferation CD86;F2 GO:0006955| immune response C1R;CD86 25757:[DB01281 DB07333] DB01281|Abatacept CD80;CD86 DB07333|N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE KDR common genes common pathways GO:0016032| viral reproduction CD80;CD86;KDR GO:0008284| positive regulation of cell proliferation KDR;CD86 25758:[DB01281 DB07840] DB01281|Abatacept CD80;CD86 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation CD86;FGFR1;CD80 GO:0008284| positive regulation of cell proliferation FGFR1;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade FGFR1;CD80;CD86 25759:[DB01281 DB05235] DB01281|Abatacept CD80;CD86 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways 25760:[DB01281 DB08164] DB01281|Abatacept CD80;CD86 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD86;DPP4;CD80 GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation CD86;DPP4 25761:[DB01281 DB01336] DB01281|Abatacept CD80;CD86 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways GO:0007165| signal transduction CHRNA2;CHRM2;CD86 25762:[DB01281 DB06655] DB01281|Abatacept CD80;CD86 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;DPP4 GO:0007165| signal transduction GLP1R;CD86 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD86;DPP4;CD80 25763:[DB01281 DB05268] DB01281|Abatacept CD80;CD86 DB05268|iCo-007 RAF1 common genes common pathways GO:0007165| signal transduction CD86;RAF1 GO:0035556| intracellular signal transduction CD80;RAF1 25764:[DB01281 DB04539] DB01281|Abatacept CD80;CD86 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways 25765:[DB01281 DB00162] DB01281|Abatacept CD80;CD86 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes common pathways GO:0007165| signal transduction HPGDS;CD86 GO:0008284| positive regulation of cell proliferation CD86;ALDH1A2 25766:[DB01281 DB05372] DB01281|Abatacept CD80;CD86 DB05372|CP-945598 CNR1 common genes common pathways GO:0007165| signal transduction CD86;CNR1 25767:[DB01281 DB02643] DB01281|Abatacept CD80;CD86 DB02643|N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate IGF1;MAOB common genes common pathways GO:0007165| signal transduction IGF1;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;IGF1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;IGF1 GO:0008284| positive regulation of cell proliferation IGF1;CD86 25768:[DB01281 DB07908] DB01281|Abatacept CD80;CD86 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways 25769:[DB01281 DB06586] DB01281|Abatacept CD80;CD86 DB06586|Cetilistat PNLIP common genes common pathways 25770:[DB01281 DB02684] DB01281|Abatacept CD80;CD86 DB02684|5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 25771:[DB01281 DB00174] DB01281|Abatacept CD80;CD86 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0016032| viral reproduction CD86;SLC1A5;CD80 GO:0046718| entry of virus into host cell SLC1A5;CD80;CD86 25772:[DB01281 DB04873] DB01281|Abatacept CD80;CD86 DB04873|Piboserod HTR4 common genes common pathways GO:0007165| signal transduction CD86;HTR4 25773:[DB01281 DB07046] DB01281|Abatacept CD80;CD86 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;MAP2K1 GO:0007165| signal transduction MAP2K1;CD86 25774:[DB01281 DB01356] DB01281|Abatacept CD80;CD86 DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation CD86;IMPA1;IMPA2;CD80 GO:0035556| intracellular signal transduction GSK3B;CD80 GO:0007165| signal transduction IMPA1;CD86;IMPA2 25775:[DB01281 DB02983] DB01281|Abatacept CD80;CD86 DB02983|Para-Mercury-Benzenesulfonic Acid CLC;ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR2;CD80 GO:0007165| signal transduction ESR2;CD86 25776:[DB01281 DB01031] DB01281|Abatacept CD80;CD86 DB01031|Ethinamate CA1;CA2 common genes common pathways 25777:[DB01281 DB06779] DB01281|Abatacept CD80;CD86 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;HPSE;CD80 GO:0008284| positive regulation of cell proliferation VEGFA;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA 25778:[DB01281 DB11937] DB01281|Abatacept CD80;CD86 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways GO:0007165| signal transduction CD86;GPR35 GO:0045893| positive regulation of transcription, DNA-dependent CD86;AHR;CD80 25779:[DB01281 DB06159] DB01281|Abatacept CD80;CD86 DB06159|Rubitecan TOP1 common genes common pathways GO:0016032| viral reproduction CD80;TOP1;CD86 25780:[DB01281 DB05501] DB01281|Abatacept CD80;CD86 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0006955| immune response CD86;CCR5 GO:0016032| viral reproduction CD86;CXCR4;CCR5;CD80 GO:0007165| signal transduction CCR5;CXCR4;CD86 25781:[DB01281 DB07771] DB01281|Abatacept CD80;CD86 DB07771|[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID KRAS;FNTA;FNTB common genes common pathways GO:0007165| signal transduction CD86;KRAS GO:0008284| positive regulation of cell proliferation CD86;KRAS 25782:[DB01281 DB03839] DB01281|Abatacept CD80;CD86 DB03839|D-Tyrosine SLC16A10 common genes common pathways 25783:[DB01281 DB02400] DB01281|Abatacept CD80;CD86 DB02400|5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways 25784:[DB01281 DB06862] DB01281|Abatacept CD80;CD86 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways GO:0035556| intracellular signal transduction CD80;CASP3 25785:[DB01281 DB06492] DB01281|Abatacept CD80;CD86 DB06492|Mirococept C3 common genes common pathways GO:0006955| immune response CD86;C3 GO:0007165| signal transduction C3;CD86 GO:0002376| immune system process C3;CD86 25786:[DB01281 DB01426] DB01281|Abatacept CD80;CD86 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways 25787:[DB01281 DB04551] DB01281|Abatacept CD80;CD86 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways 25788:[DB01281 DB12520] DB01281|Abatacept CD80;CD86 DB12520|Plozalizumab CCR2 common genes common pathways GO:0006955| immune response CCR2;CD86 GO:0016032| viral reproduction CD80;CCR2;CD86 GO:0007165| signal transduction CCR2;CD86 25789:[DB01281 DB07558] DB01281|Abatacept CD80;CD86 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways GO:0016032| viral reproduction CD80;PSMA7;CD86 25790:[DB01281 DB08830] DB01281|Abatacept CD80;CD86 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways 25791:[DB01281 DB07958] DB01281|Abatacept CD80;CD86 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways 25792:[DB01281 DB00462] DB01281|Abatacept CD80;CD86 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CHRM1;CHRM2;CD86;CHRM3 25793:[DB01281 DB04850] DB01281|Abatacept CD80;CD86 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways 25794:[DB01281 DB05142] DB01281|Abatacept CD80;CD86 DB05142|ND7001 PDE2A;PDE2A common genes common pathways GO:0007165| signal transduction PDE2A;CD86 25795:[DB01281 DB08949] DB01281|Abatacept CD80;CD86 DB08949|Inositol nicotinate HCAR3;HCAR2;ATP5B;DGAT2;SLC5A8 common genes common pathways GO:0007165| signal transduction CD86;HCAR3;HCAR2 25796:[DB01281 DB06266] DB01281|Abatacept CD80;CD86 DB06266|Lonidamine CFTR;HK1 common genes common pathways 25797:[DB01281 DB04724] DB01281|Abatacept CD80;CD86 DB04724|(S)-2-((S)-3-ISOBUTYL-2,5-DIOXO-4-QUINOLIN-3-YLMETHYL-[1,4]DIAZEPAN-1YL)-N-METHYL-3-NAPHTALEN-2-YL-PROPIONAMIDE ITGAL common genes common pathways GO:0007165| signal transduction CD86;ITGAL 25798:[DB01281 DB04858] DB01281|Abatacept CD80;CD86 DB04858|Tirapazamine CYP2E1 common genes common pathways 25799:[DB01281 DB03348] DB01281|Abatacept CD80;CD86 DB03348|Huperzine B ACHE common genes common pathways 25800:[DB01281 DB05930] DB01281|Abatacept CD80;CD86 DB05930|SB-559448 MPL common genes common pathways 25801:[DB01281 DB01864] DB01281|Abatacept CD80;CD86 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways 25802:[DB01281 DB11672] DB01281|Abatacept CD80;CD86 DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;PPARG GO:0007165| signal transduction VDR;CD86;PPARG 25803:[DB01281 DB07528] DB01281|Abatacept CD80;CD86 DB07528|3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one KDR common genes common pathways GO:0016032| viral reproduction KDR;CD86;CD80 GO:0008284| positive regulation of cell proliferation KDR;CD86 25804:[DB01281 DB05457] DB01281|Abatacept CD80;CD86 DB05457|OSI-7904L TYMS common genes common pathways 25805:[DB01281 DB02032] DB01281|Abatacept CD80;CD86 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 25806:[DB01281 DB00668] DB01281|Abatacept CD80;CD86 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0006955| immune response CD86;TNF GO:0035556| intracellular signal transduction ADRA1A;CD80;ADRA1B GO:0007165| signal transduction ADRB2;ADRA2B;ADRA1B;ADRA1D;ADRA2A;CD86;ADRA1A;ADRB1 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;TNF GO:0045893| positive regulation of transcription, DNA-dependent TNF;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;ADRA2A;ADRA1D 25807:[DB01281 DB04489] DB01281|Abatacept CD80;CD86 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 25808:[DB01281 DB11081] DB01281|Abatacept CD80;CD86 DB11081|Aluminum chloride GLUD1 common genes common pathways 25809:[DB01281 DB09295] DB01281|Abatacept CD80;CD86 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 25810:[DB01281 DB06011] DB01281|Abatacept CD80;CD86 DB06011|AMG-222 DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD86;DPP4;CD80 GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 25811:[DB01281 DB00811] DB01281|Abatacept CD80;CD86 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0006955| immune response ENPP1;CD86 25812:[DB01281 DB05395] DB01281|Abatacept CD80;CD86 DB05395|Amibegron ADRB3 common genes common pathways GO:0007165| signal transduction CD86;ADRB3 25813:[DB01281 DB08098] DB01281|Abatacept CD80;CD86 DB08098|{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid AKR1B1 common genes common pathways 25814:[DB01281 DB00577] DB01281|Abatacept CD80;CD86 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways 25815:[DB01281 DB01433] DB01281|Abatacept CD80;CD86 DB01433|Methadyl acetate OPRM1 common genes common pathways GO:0007165| signal transduction OPRM1;CD86 25816:[DB01281 DB05678] DB01281|Abatacept CD80;CD86 DB05678|SLx-4090 MTTP common genes common pathways 25817:[DB01281 DB01397] DB01281|Abatacept CD80;CD86 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 25818:[DB01281 DB06755] DB01281|Abatacept CD80;CD86 DB06755|Beta carotene BCO1;VLDLR;RBP1;RBP2;RBP3;RBP4;RBP5 common genes common pathways GO:0007165| signal transduction VLDLR;CD86 25819:[DB01281 DB01017] DB01281|Abatacept CD80;CD86 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0045086| positive regulation of interleukin-2 biosynthetic process CD80;IL1B;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;IL1B;CD80 GO:0008284| positive regulation of cell proliferation CD86;IL1B;VEGFA GO:0007165| signal transduction CD86;IL1B;CASP1 GO:0006955| immune response IL1B;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation VEGFA;CD80 GO:0035556| intracellular signal transduction CASP3;CD80 25820:[DB01281 DB03283] DB01281|Abatacept CD80;CD86 DB03283|beta-L-fucose ACHE common genes common pathways 25821:[DB01281 DB03712] DB01281|Abatacept CD80;CD86 DB03712|RU85053 SRC common genes common pathways GO:0007165| signal transduction SRC;CD86 GO:0035556| intracellular signal transduction CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction SRC;CD80;CD86 GO:0031295| T cell costimulation SRC;CD80;CD86 GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 25822:[DB01281 DB01728] DB01281|Abatacept CD80;CD86 DB01728|3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-Glycerol RHO common genes common pathways GO:0007165| signal transduction CD86;RHO 25823:[DB01281 DB02391] DB01281|Abatacept CD80;CD86 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways GO:0006955| immune response PNP;CD86 25824:[DB01281 DB02020] DB01281|Abatacept CD80;CD86 DB02020|Alrestatin AKR1B1 common genes common pathways 25825:[DB01281 DB02497] DB01281|Abatacept CD80;CD86 DB02497|L-Alpha-Glycerophosphorylserine ANXA5 common genes common pathways GO:0007165| signal transduction ANXA5;CD86 25826:[DB01281 DB14498] DB01281|Abatacept CD80;CD86 DB14498|Potassium acetate ATP1A1 common genes common pathways 25827:[DB01281 DB05478] DB01281|Abatacept CD80;CD86 DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways 25828:[DB01281 DB00456] DB01281|Abatacept CD80;CD86 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 25829:[DB01281 DB01178] DB01281|Abatacept CD80;CD86 DB01178|Chlormezanone TSPO common genes common pathways GO:0007165| signal transduction CD86;TSPO 25830:[DB01281 DB03214] DB01281|Abatacept CD80;CD86 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways 25831:[DB01281 DB06987] DB01281|Abatacept CD80;CD86 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways GO:0002376| immune system process LTF;CD86 25832:[DB01281 DB11623] DB01281|Abatacept CD80;CD86 DB11623|Candoxatrilat MME common genes common pathways 25833:[DB01281 DB02299] DB01281|Abatacept CD80;CD86 DB02299|Arginineamide KCNA4 common genes common pathways 25834:[DB01281 DB11582] DB01281|Abatacept CD80;CD86 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0007165| signal transduction GABRA5;GABRD;GABRP;CD86;GABRE;GABRB1;GABRQ;GABRA6;GABRB3 GO:0006955| immune response TNFSF11;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;TNFSF11 25835:[DB01281 DB03062] DB01281|Abatacept CD80;CD86 DB03062|(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone NMT1;NMT1 common genes common pathways 25836:[DB01281 DB08799] DB01281|Abatacept CD80;CD86 DB08799|Antazoline HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 25837:[DB01281 DB03934] DB01281|Abatacept CD80;CD86 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways 25838:[DB01281 DB06081] DB01281|Abatacept CD80;CD86 DB06081|Caplacizumab VWF common genes common pathways 25839:[DB01281 DB12637] DB01281|Abatacept CD80;CD86 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0007165| signal transduction NR3C1;CD86;ADGRD1 25840:[DB01281 DB07000] DB01281|Abatacept CD80;CD86 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways GO:0035556| intracellular signal transduction BRAF;CD80 GO:0007165| signal transduction CD86;BRAF 25841:[DB01281 DB07070] DB01281|Abatacept CD80;CD86 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARD;CD80 GO:0008284| positive regulation of cell proliferation CD86;PPARD 25842:[DB01281 DB05447] DB01281|Abatacept CD80;CD86 DB05447|AVI-4557 HNF4A common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;HNF4A;CD80 25843:[DB01281 DB07485] DB01281|Abatacept CD80;CD86 DB07485|4,4'-cyclohexane-1,1-diyldiphenol ESRRG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESRRG;CD80 25844:[DB01281 DB00982] DB01281|Abatacept CD80;CD86 DB00982|Isotretinoin RARA common genes common pathways GO:0045630| positive regulation of T-helper 2 cell differentiation RARA;CD86 GO:0045893| positive regulation of transcription, DNA-dependent RARA;CD80;CD86 GO:0008284| positive regulation of cell proliferation CD86;RARA GO:0007165| signal transduction RARA;CD86 25845:[DB01281 DB05107] DB01281|Abatacept CD80;CD86 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways 25846:[DB01281 DB01990] DB01281|Abatacept CD80;CD86 DB01990|Cholesterol sulfate RORA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;RORA;CD80 25847:[DB01281 DB03682] DB01281|Abatacept CD80;CD86 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways 25848:[DB01281 DB02868] DB01281|Abatacept CD80;CD86 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways 25849:[DB01281 DB01328] DB01281|Abatacept CD80;CD86 DB01328|Cefonicid mrcA;ALB common genes common pathways 25850:[DB01281 DB04817] DB01281|Abatacept CD80;CD86 DB04817|Metamizole PTGS1;CYP2B6;CYP3A4 common genes common pathways 25851:[DB01281 DB00202] DB01281|Abatacept CD80;CD86 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1;CHRNA7 GO:0007165| signal transduction CHRM2;CHRM1;CHRNA7;CHRM3;CD86;CHRNA10 25852:[DB01281 DB13178] DB01281|Abatacept CD80;CD86 DB13178|Inositol SLC5A3 common genes common pathways 25853:[DB01281 DB12670] DB01281|Abatacept CD80;CD86 DB12670|Rolofylline ADORA1 common genes common pathways GO:0007165| signal transduction ADORA1;CD86 25854:[DB01281 DB03591] DB01281|Abatacept CD80;CD86 DB03591|RU82209 SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0002376| immune system process CD86;SRC GO:0035556| intracellular signal transduction SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction CD86;SRC;CD80 GO:0007165| signal transduction CD86;SRC 25855:[DB01281 DB05243] DB01281|Abatacept CD80;CD86 DB05243|XL019 JAK2 common genes common pathways GO:0002250| adaptive immune response CD86;JAK2 GO:0008284| positive regulation of cell proliferation JAK2;CD86 GO:0002376| immune system process JAK2;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;JAK2 GO:0035556| intracellular signal transduction JAK2;CD80 GO:0007165| signal transduction JAK2;CD86 25856:[DB01281 DB11692] DB01281|Abatacept CD80;CD86 DB11692|Pavinetant TACR3 common genes common pathways GO:0007165| signal transduction TACR3;CD86 25857:[DB01281 DB07157] DB01281|Abatacept CD80;CD86 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways 25858:[DB01281 DB06282] DB01281|Abatacept CD80;CD86 DB06282|Levocetirizine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 25859:[DB01281 DB01404] DB01281|Abatacept CD80;CD86 DB01404|Ginseng IL6;PTGS2;AHR common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;CD80 GO:0006955| immune response CD86;IL6 GO:0008284| positive regulation of cell proliferation PTGS2;CD86;IL6 GO:0045893| positive regulation of transcription, DNA-dependent CD86;IL6;AHR;CD80 25860:[DB01281 DB08006] DB01281|Abatacept CD80;CD86 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways 25861:[DB01281 DB01364] DB01281|Abatacept CD80;CD86 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0007165| signal transduction CD86;ADRA1A GO:0035556| intracellular signal transduction ADRA1A;CD80 25862:[DB01281 DB03769] DB01281|Abatacept CD80;CD86 DB03769|D-Eritadenine AHCY common genes common pathways 25863:[DB01281 DB04682] DB01281|Abatacept CD80;CD86 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 25864:[DB01281 DB07787] DB01281|Abatacept CD80;CD86 DB07787|5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE PARP1 common genes common pathways 25865:[DB01281 DB02426] DB01281|Abatacept CD80;CD86 DB02426|Carboxyatractyloside SLC25A4 common genes common pathways GO:0016032| viral reproduction CD80;SLC25A4;CD86 25866:[DB01281 DB06997] DB01281|Abatacept CD80;CD86 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;MET;CD80 GO:0046854| phosphatidylinositol phosphorylation CD86;CD80;MET GO:0007165| signal transduction CD86;MET 25867:[DB01281 DB07966] DB01281|Abatacept CD80;CD86 DB07966|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile SRC common genes common pathways GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0007165| signal transduction SRC;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction CD80;SRC;CD86 GO:0035556| intracellular signal transduction CD80;SRC 25868:[DB01281 DB05464] DB01281|Abatacept CD80;CD86 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways GO:0007165| signal transduction NFKB1;NFKB2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;NFKB1;CD80 25869:[DB01281 DB04381] DB01281|Abatacept CD80;CD86 DB04381|Crotonaldehyde ALDH2 common genes common pathways 25870:[DB01281 DB01644] DB01281|Abatacept CD80;CD86 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways 25871:[DB01281 DB03991] DB01281|Abatacept CD80;CD86 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways 25872:[DB01281 DB08350] DB01281|Abatacept CD80;CD86 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;CD80 25873:[DB01281 DB08743] DB01281|Abatacept CD80;CD86 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD86;DPP4;CD80 25874:[DB01281 DB05200] DB01281|Abatacept CD80;CD86 DB05200|AT2220 GAA common genes common pathways 25875:[DB01281 DB14707] DB01281|Abatacept CD80;CD86 DB14707|Cemiplimab PDCD1 common genes common pathways GO:0031295| T cell costimulation PDCD1;CD80;CD86 GO:0002376| immune system process CD86;PDCD1 GO:0007165| signal transduction CD86;PDCD1 25876:[DB01281 DB12960] DB01281|Abatacept CD80;CD86 DB12960|INCB-9471 CCR5 common genes common pathways GO:0016032| viral reproduction CD86;CCR5;CD80 GO:0006955| immune response CD86;CCR5 GO:0007165| signal transduction CD86;CCR5 25877:[DB01281 DB04953] DB01281|Abatacept CD80;CD86 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways 25878:[DB01281 DB09333] DB01281|Abatacept CD80;CD86 DB09333|Iopodic acid DIO3;ALB common genes common pathways 25879:[DB01281 DB06707] DB01281|Abatacept CD80;CD86 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0007165| signal transduction ADRA2C;ADRA2B;ADRA2A;CD86 GO:0008284| positive regulation of cell proliferation CD86;ADRA2A 25880:[DB01281 DB07602] DB01281|Abatacept CD80;CD86 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways GO:0046854| phosphatidylinositol phosphorylation CD86;EGFR;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;EGFR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;CD86;CD80 GO:0008284| positive regulation of cell proliferation EGFR;CD86 GO:0046718| entry of virus into host cell CD80;CD86;EGFR GO:0007165| signal transduction CD86;EGFR GO:0035556| intracellular signal transduction CD80;EGFR 25881:[DB01281 DB12615] DB01281|Abatacept CD80;CD86 DB12615|Plazomicin rpsN;rpsK;SLC47A1;SLC47A2 common genes common pathways 25882:[DB01281 DB08818] DB01281|Abatacept CD80;CD86 DB08818|Hyaluronic acid CD44;ICAM1;HMMR;NCAN;VCAN;C1QBP;HAPLN1;HAPLN3;HAPLN4;HABP2;LAYN;STAB2;TNFAIP6;IMPG2;HABP4 common genes common pathways GO:0046718| entry of virus into host cell ICAM1;CD86;CD80 GO:0007165| signal transduction CD86;TNFAIP6 GO:0016032| viral reproduction CD86;ICAM1;C1QBP;CD80 GO:0006955| immune response C1QBP;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;CD44;ICAM1 GO:0002376| immune system process C1QBP;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade C1QBP;CD86;CD80 GO:0002250| adaptive immune response C1QBP;CD86 25883:[DB01281 DB07609] DB01281|Abatacept CD80;CD86 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways 25884:[DB01281 DB03323] DB01281|Abatacept CD80;CD86 DB03323|Maltose AMY2B;aglA common genes common pathways 25885:[DB01281 DB04617] DB01281|Abatacept CD80;CD86 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways 25886:[DB01281 DB00576] DB01281|Abatacept CD80;CD86 DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways 25887:[DB01281 DB01213] DB01281|Abatacept CD80;CD86 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways 25888:[DB01281 DB00718] DB01281|Abatacept CD80;CD86 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways 25889:[DB01281 DB04463] DB01281|Abatacept CD80;CD86 DB04463|3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol CBR1;CBR1 common genes common pathways 25890:[DB01281 DB00368] DB01281|Abatacept CD80;CD86 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0007165| signal transduction ADRB1;ADRA1A;ADRA2A;CD86;ADRB3;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRB2 GO:0008284| positive regulation of cell proliferation ADRA2A;CD86;ADRA1D 25891:[DB01281 DB08238] DB01281|Abatacept CD80;CD86 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways GO:0007165| signal transduction CD86;FGF1 GO:0008284| positive regulation of cell proliferation FGF1;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;FGF1;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;FGF1;CD86 25892:[DB01281 DB03535] DB01281|Abatacept CD80;CD86 DB03535|Z-Pro-Prolinal PREP common genes common pathways 25893:[DB01281 DB00151] DB01281|Abatacept CD80;CD86 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways 25894:[DB01281 DB02751] DB01281|Abatacept CD80;CD86 DB02751|Glycocyamine GAMT common genes common pathways 25895:[DB01281 DB03185] DB01281|Abatacept CD80;CD86 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 25896:[DB01281 DB03453] DB01281|Abatacept CD80;CD86 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways GO:0002250| adaptive immune response IL2;CD86 GO:0008284| positive regulation of cell proliferation IL2;CD86 GO:0002376| immune system process CD86;IL2 GO:0006955| immune response CD86;IL2 25897:[DB01281 DB09292] DB01281|Abatacept CD80;CD86 DB09292|Sacubitril MME;SLCO1B1;SLCO1B3 common genes common pathways 25898:[DB01281 DB08024] DB01281|Abatacept CD80;CD86 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD80;DPP4;CD86 25899:[DB01281 DB09038] DB01281|Abatacept CD80;CD86 DB09038|Empagliflozin SLC5A2 common genes common pathways 25900:[DB01281 DB07586] DB01281|Abatacept CD80;CD86 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways 25901:[DB01281 DB03516] DB01281|Abatacept CD80;CD86 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways 25902:[DB01281 DB07330] DB01281|Abatacept CD80;CD86 DB07330|trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium PARP1 common genes common pathways 25903:[DB01281 DB03128] DB01281|Abatacept CD80;CD86 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0007165| signal transduction CHRNA7;CHRM1;CHRM2;CD86;CHRM4;CHRM3 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7;CHRM1 25904:[DB01281 DB08888] DB01281|Abatacept CD80;CD86 DB08888|Ocriplasmin FN1;A2M;SERPINF2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;FN1 25905:[DB01281 DB03824] DB01281|Abatacept CD80;CD86 DB03824|7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline PNMT common genes common pathways 25906:[DB01281 DB01306] DB01281|Abatacept CD80;CD86 DB01306|Insulin Aspart INSR common genes common pathways GO:0035556| intracellular signal transduction INSR;CD80 GO:0008284| positive regulation of cell proliferation INSR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;INSR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent INSR;CD86;CD80 25907:[DB01281 DB02198] DB01281|Abatacept CD80;CD86 DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways 25908:[DB01281 DB00148] DB01281|Abatacept CD80;CD86 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways 25909:[DB01281 DB07780] DB01281|Abatacept CD80;CD86 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways GO:0007165| signal transduction KRAS;CD86 GO:0016032| viral reproduction CD86;FDPS;CD80 GO:0008284| positive regulation of cell proliferation KRAS;CD86 25910:[DB01281 DB08053] DB01281|Abatacept CD80;CD86 DB08053|1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80;CD86 GO:0007165| signal transduction SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD86;SRC;CD80 25911:[DB01281 DB06090] DB01281|Abatacept CD80;CD86 DB06090|Bradanicline CHRNA7 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;CD86 GO:0007165| signal transduction CD86;CHRNA7 25912:[DB01281 DB01614] DB01281|Abatacept CD80;CD86 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;CD86 GO:0007165| signal transduction CD86;DRD2;ADRA1A;HTR2A;HTR1A;DRD1;ADRA1B GO:0046718| entry of virus into host cell CD86;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0035556| intracellular signal transduction CD80;ADRA1B;DRD2;ADRA1A 25913:[DB01281 DB13151] DB01281|Abatacept CD80;CD86 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0002376| immune system process FGA;CD86;FGB GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F7;F10 GO:0002250| adaptive immune response FGA;CD86;FGB GO:0008284| positive regulation of cell proliferation F2;CD86 GO:0007165| signal transduction CD86;FGA;FGB 25914:[DB01281 DB01610] DB01281|Abatacept CD80;CD86 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways 25915:[DB01281 DB11914] DB01281|Abatacept CD80;CD86 DB11914|Lebrikizumab IL13;IL13 common genes common pathways GO:0006955| immune response IL13;CD86 25916:[DB01281 DB01382] DB01281|Abatacept CD80;CD86 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0007165| signal transduction CD86;ABCC8 25917:[DB01281 DB07448] DB01281|Abatacept CD80;CD86 DB07448|(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid LAP3 common genes common pathways 25918:[DB01281 DB03279] DB01281|Abatacept CD80;CD86 DB03279|Dodecyl-Alpha-D-Maltoside RARG common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;RARG 25919:[DB01281 DB08836] DB01281|Abatacept CD80;CD86 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways 25920:[DB01281 DB00165] DB01281|Abatacept CD80;CD86 DB00165|Pyridoxine PDXK;CYP1A1 common genes common pathways 25921:[DB01281 DB00714] DB01281|Abatacept CD80;CD86 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0008284| positive regulation of cell proliferation DRD3;ADRA2A;HTR2B;CD86;HTR1A;HTR2A GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction HTR1B;DRD2;HTR2B;HTR2C;ADRA2A;CD86;DRD3;DRD5;DRD1;HTR1D;HTR1A;DRD4;ADRA2C;HTR2A;ADRA2B GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 25922:[DB01281 DB03495] DB01281|Abatacept CD80;CD86 DB03495|4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose AMY2A;AMY2A common genes common pathways 25923:[DB01281 DB01600] DB01281|Abatacept CD80;CD86 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 25924:[DB01281 DB09099] DB01281|Abatacept CD80;CD86 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0007165| signal transduction SSTR4;CD86;SSTR2;SSTR1;SSTR5;SSTR3 25925:[DB01281 DB03223] DB01281|Abatacept CD80;CD86 DB03223|Diphthamide EEF2 common genes common pathways 25926:[DB01281 DB06843] DB01281|Abatacept CD80;CD86 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways GO:0007165| signal transduction CD86;GNAS;ADCY2 GO:0035556| intracellular signal transduction ADCY2;ADCY5;CD80 25927:[DB01281 DB08675] DB01281|Abatacept CD80;CD86 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways 25928:[DB01281 DB00926] DB01281|Abatacept CD80;CD86 DB00926|Etretinate RARA;RXRA;RARB;RXRG;RXRB;RARG;CYP19A1;CYP26A1;CRABP1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;RARA;RXRA;CD86 GO:0008284| positive regulation of cell proliferation CD86;RARB;RARG;RARA GO:0045630| positive regulation of T-helper 2 cell differentiation RARA;CD86 GO:0016032| viral reproduction CD80;RXRA;CD86 GO:0007165| signal transduction CD86;RARB;RARA;CRABP1 25929:[DB01281 DB11611] DB01281|Abatacept CD80;CD86 DB11611|Lifitegrast ITGAL;CYP2C9;SLCO1A2;SLCO2B1 common genes common pathways GO:0007165| signal transduction CD86;ITGAL 25930:[DB01281 DB00039] DB01281|Abatacept CD80;CD86 DB00039|Palifermin FGFR2;NRP1;FGFR1;FGFR4;FGFR3;HSPG2 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation FGFR4;CD86;FGFR3;FGFR2;FGFR1;CD80 GO:0008284| positive regulation of cell proliferation FGFR3;FGFR4;CD86;FGFR1;FGFR2 GO:0051897| positive regulation of protein kinase B signaling cascade FGFR4;CD86;FGFR3;FGFR2;CD80;FGFR1 GO:0007165| signal transduction NRP1;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation NRP1;CD80 25931:[DB01281 DB06699] DB01281|Abatacept CD80;CD86 DB06699|Degarelix GNRHR common genes common pathways GO:0007165| signal transduction GNRHR;CD86 25932:[DB01281 DB05687] DB01281|Abatacept CD80;CD86 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HTR2A GO:0046718| entry of virus into host cell HTR2A;CD80;CD86 GO:0007165| signal transduction DRD2;CD86;HTR2A GO:0035556| intracellular signal transduction DRD2;CD80 GO:0016032| viral reproduction CD86;HTR2A;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A 25933:[DB01281 DB03314] DB01281|Abatacept CD80;CD86 DB03314|Fluorotryptophane TPI1;GSTM1 common genes common pathways 25934:[DB01281 DB01400] DB01281|Abatacept CD80;CD86 DB01400|Neostigmine ACHE;BCHE common genes common pathways 25935:[DB01281 DB04972] DB01281|Abatacept CD80;CD86 DB04972|Canfosfamide GSTP1 common genes common pathways 25936:[DB01281 DB06822] DB01281|Abatacept CD80;CD86 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0007165| signal transduction CD86;CXCL12 GO:0006955| immune response CXCL12;CD86 GO:0008284| positive regulation of cell proliferation CXCL12;CD86 25937:[DB01281 DB00200] DB01281|Abatacept CD80;CD86 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways 25938:[DB01281 DB05578] DB01281|Abatacept CD80;CD86 DB05578|Ramucirumab KDR common genes common pathways GO:0016032| viral reproduction CD80;KDR;CD86 GO:0008284| positive regulation of cell proliferation CD86;KDR 25939:[DB01281 DB07187] DB01281|Abatacept CD80;CD86 DB07187|6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE AKR1B1 common genes common pathways 25940:[DB01281 DB03974] DB01281|Abatacept CD80;CD86 DB03974|L-Homoarginine NOS3 common genes common pathways 25941:[DB01281 DB09564] DB01281|Abatacept CD80;CD86 DB09564|Insulin Degludec INSR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade INSR;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;INSR;CD80 GO:0008284| positive regulation of cell proliferation CD86;INSR GO:0035556| intracellular signal transduction CD80;INSR 25942:[DB01281 DB14517] DB01281|Abatacept CD80;CD86 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;APP;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP 25943:[DB01281 DB01212] DB01281|Abatacept CD80;CD86 DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 25944:[DB01281 DB03476] DB01281|Abatacept CD80;CD86 DB03476|Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 25945:[DB01281 DB02633] DB01281|Abatacept CD80;CD86 DB02633|Cibacron Blue NQO1;GSTP1 common genes common pathways 25946:[DB01281 DB08166] DB01281|Abatacept CD80;CD86 DB08166|(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile PIM1 common genes common pathways 25947:[DB01281 DB06931] DB01281|Abatacept CD80;CD86 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 25948:[DB01281 DB00357] DB01281|Abatacept CD80;CD86 DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways 25949:[DB01281 DB08176] DB01281|Abatacept CD80;CD86 DB08176|(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE MAOB common genes common pathways 25950:[DB01281 DB13144] DB01281|Abatacept CD80;CD86 DB13144|Lenograstim CSF3R common genes common pathways GO:0007165| signal transduction CSF3R;CD86 25951:[DB01281 DB06191] DB01281|Abatacept CD80;CD86 DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways 25952:[DB01281 DB08104] DB01281|Abatacept CD80;CD86 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways 25953:[DB01281 DB00884] DB01281|Abatacept CD80;CD86 DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0016032| viral reproduction CD86;FDPS;CD80 GO:0008284| positive regulation of cell proliferation PTGS2;CD86 25954:[DB01281 DB01014] DB01281|Abatacept CD80;CD86 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0008284| positive regulation of cell proliferation CD86;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;PPARG 25955:[DB01281 DB04334] DB01281|Abatacept CD80;CD86 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways 25956:[DB01281 DB14041] DB01281|Abatacept CD80;CD86 DB14041|Fremanezumab CALCA;CALCB common genes common pathways GO:0007165| signal transduction CD86;CALCB 25957:[DB01281 DB07061] DB01281|Abatacept CD80;CD86 DB07061|1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL NMT2 common genes common pathways 25958:[DB01281 DB05265] DB01281|Abatacept CD80;CD86 DB05265|Ecabet NOXO1;ureC common genes common pathways 25959:[DB01281 DB09309] DB01281|Abatacept CD80;CD86 DB09309|Kitasamycin CYP3A4 common genes common pathways 25960:[DB01281 DB05479] DB01281|Abatacept CD80;CD86 DB05479|CZEN 002 MC1R common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;MC1R;CD80 GO:0035556| intracellular signal transduction CD80;MC1R GO:0007165| signal transduction CD86;MC1R 25961:[DB01281 DB01056] DB01281|Abatacept CD80;CD86 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways 25962:[DB01281 DB04876] DB01281|Abatacept CD80;CD86 DB04876|Vildagliptin DPP4 common genes common pathways GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD80;CD86;DPP4 25963:[DB01281 DB02393] DB01281|Abatacept CD80;CD86 DB02393|D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate PFKFB1 common genes common pathways 25964:[DB01281 DB08057] DB01281|Abatacept CD80;CD86 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways GO:0016032| viral reproduction CD80;LCK;CD86 GO:0031295| T cell costimulation LCK;CD86;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;LCK GO:0051897| positive regulation of protein kinase B signaling cascade CD80;LCK;CD86 25965:[DB01281 DB07766] DB01281|Abatacept CD80;CD86 DB07766|(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} CAMK2A;CDK16 common genes common pathways GO:0035556| intracellular signal transduction CAMK2A;CD80 25966:[DB01281 DB11077] DB01281|Abatacept CD80;CD86 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0006955| immune response ENPP1;CD86 25967:[DB01281 DB11093] DB01281|Abatacept CD80;CD86 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0008284| positive regulation of cell proliferation S100A13;CASR;S100B;CD86;CIB1;CALR GO:0007165| signal transduction CACNA1I;CD86;SPARC;CASR;S100A6;SRI GO:0035556| intracellular signal transduction CD80;CAPS 25968:[DB01281 DB12110] DB01281|Abatacept CD80;CD86 DB12110|m-Chlorophenylpiperazine HTR2C common genes common pathways GO:0007165| signal transduction HTR2C;CD86 25969:[DB01281 DB08358] DB01281|Abatacept CD80;CD86 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0007165| signal transduction MAPKAPK3;CD86 25970:[DB01281 DB01354] DB01281|Abatacept CD80;CD86 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GABRA5;CD86;GABRA6;CHRNA4;GRIA2;CHRNA7 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 25971:[DB01281 DB05225] DB01281|Abatacept CD80;CD86 DB05225|AM103 ALOX5AP common genes common pathways 25972:[DB01281 DB11948] DB01281|Abatacept CD80;CD86 DB11948|Lapachone RBP3 common genes common pathways 25973:[DB01281 DB03672] DB01281|Abatacept CD80;CD86 DB03672|9-N-Phenylmethylamino-Tacrine BCHE common genes common pathways 25974:[DB01281 DB01255] DB01281|Abatacept CD80;CD86 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0007165| signal transduction CD86;TAAR1 25975:[DB01281 DB07004] DB01281|Abatacept CD80;CD86 DB07004|2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide S100B common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;S100B 25976:[DB01281 DB04327] DB01281|Abatacept CD80;CD86 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0008284| positive regulation of cell proliferation PTEN;CD86 25977:[DB01281 DB03206] DB01281|Abatacept CD80;CD86 DB03206|Duvoglustat MAN1B1;xylA common genes common pathways 25978:[DB01281 DB03389] DB01281|Abatacept CD80;CD86 DB03389|alpha-D-Xylopyranose LCT common genes common pathways 25979:[DB01281 DB08048] DB01281|Abatacept CD80;CD86 DB08048|4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 GO:0007165| signal transduction ESR1;CD86 25980:[DB01281 DB08688] DB01281|Abatacept CD80;CD86 DB08688|undecan-2-one ACOT13 common genes common pathways 25981:[DB01281 DB06880] DB01281|Abatacept CD80;CD86 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 25982:[DB01281 DB04263] DB01281|Abatacept CD80;CD86 DB04263|Geneticin ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ODC1 25983:[DB01281 DB08693] DB01281|Abatacept CD80;CD86 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 25984:[DB01281 DB00127] DB01281|Abatacept CD80;CD86 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CASR;ODC1 GO:0007165| signal transduction ADRB1;CD86;CASR;ADRB2 25985:[DB01281 DB06420] DB01281|Abatacept CD80;CD86 DB06420|Annamycin TOP2A common genes common pathways 25986:[DB01281 DB07382] DB01281|Abatacept CD80;CD86 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways 25987:[DB01281 DB01712] DB01281|Abatacept CD80;CD86 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways 25988:[DB01281 DB00301] DB01281|Abatacept CD80;CD86 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways 25989:[DB01281 DB00547] DB01281|Abatacept CD80;CD86 DB00547|Desoximetasone NR3C1 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 25990:[DB01281 DB00868] DB01281|Abatacept CD80;CD86 DB00868|Benzonatate SCN5A common genes common pathways 25991:[DB01281 DB07795] DB01281|Abatacept CD80;CD86 DB07795|Fisetin CDK6 common genes common pathways GO:0007165| signal transduction CD86;CDK6 25992:[DB01281 DB03096] DB01281|Abatacept CD80;CD86 DB03096|N-Aminoethylmorpholine CTSD common genes common pathways 25993:[DB01281 DB09103] DB01281|Abatacept CD80;CD86 DB09103|Ancestim KIT common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;KIT GO:0051897| positive regulation of protein kinase B signaling cascade CD86;KIT;CD80 GO:0046854| phosphatidylinositol phosphorylation KIT;CD80;CD86 GO:0035556| intracellular signal transduction CD80;KIT GO:0007165| signal transduction CD86;KIT 25994:[DB01281 DB12731] DB01281|Abatacept CD80;CD86 DB12731|Daporinad NAMPT common genes common pathways GO:0007165| signal transduction NAMPT;CD86 GO:0008284| positive regulation of cell proliferation NAMPT;CD86 25995:[DB01281 DB07201] DB01281|Abatacept CD80;CD86 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways 25996:[DB01281 DB05077] DB01281|Abatacept CD80;CD86 DB05077|SLV319 CNR1 common genes common pathways GO:0007165| signal transduction CD86;CNR1 25997:[DB01281 DB05446] DB01281|Abatacept CD80;CD86 DB05446|LJP 1082 APOH common genes common pathways 25998:[DB01281 DB04573] DB01281|Abatacept CD80;CD86 DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0007165| signal transduction ESR1;ESR2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;ESR2;CD86 25999:[DB01281 DB06963] DB01281|Abatacept CD80;CD86 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways 26000:[DB01281 DB00893] DB01281|Abatacept CD80;CD86 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0006955| immune response FTH1;CD86 26001:[DB01281 DB00128] DB01281|Abatacept CD80;CD86 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0016032| viral reproduction CD86;ACY3;CD80 GO:0002376| immune system process ADSS;CD86;ADSSL1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ASPH;CD80 26002:[DB01281 DB06321] DB01281|Abatacept CD80;CD86 DB06321|R-348 JAK3 common genes common pathways GO:0002376| immune system process CD86;JAK3 GO:0002250| adaptive immune response CD86;JAK3 GO:0035556| intracellular signal transduction JAK3;CD80 26003:[DB01281 DB02281] DB01281|Abatacept CD80;CD86 DB02281|Formycin MTAP common genes common pathways 26004:[DB01281 DB02598] DB01281|Abatacept CD80;CD86 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways 26005:[DB01281 DB05209] DB01281|Abatacept CD80;CD86 DB05209|SYM001 RHD common genes common pathways 26006:[DB01281 DB04437] DB01281|Abatacept CD80;CD86 DB04437|Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline FABP4 common genes common pathways 26007:[DB01281 DB14639] DB01281|Abatacept CD80;CD86 DB14639|Boldenone undecylenate AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 26008:[DB01281 DB06802] DB01281|Abatacept CD80;CD86 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26009:[DB01281 DB01764] DB01281|Abatacept CD80;CD86 DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways 26010:[DB01281 DB00797] DB01281|Abatacept CD80;CD86 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0007165| signal transduction HRH1;ADRA2C;HRH2;ADRA2B;ADRA1A;ADRA2A;CD86 GO:0035556| intracellular signal transduction ADRA1A;CD80 GO:0006955| immune response CD86;HRH2 GO:0008284| positive regulation of cell proliferation ADRA2A;CD86 26011:[DB01281 DB00345] DB01281|Abatacept CD80;CD86 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways 26012:[DB01281 DB02783] DB01281|Abatacept CD80;CD86 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 26013:[DB01281 DB07628] DB01281|Abatacept CD80;CD86 DB07628|6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one PKM common genes common pathways 26014:[DB01281 DB07895] DB01281|Abatacept CD80;CD86 DB07895|ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID FNTB;FNTA common genes common pathways 26015:[DB01281 DB06444] DB01281|Abatacept CD80;CD86 DB06444|Dexanabinol TNF common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;TNF;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;TNF;CD86 GO:0006955| immune response CD86;TNF 26016:[DB01281 DB05595] DB01281|Abatacept CD80;CD86 DB05595|Farletuzumab FOLR1 common genes common pathways 26017:[DB01281 DB08174] DB01281|Abatacept CD80;CD86 DB08174|5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 26018:[DB01281 DB06103] DB01281|Abatacept CD80;CD86 DB06103|VX-148 IMPDH1;IMPDH2 common genes common pathways 26019:[DB01281 DB00061] DB01281|Abatacept CD80;CD86 DB00061|Pegademase bovine GRB2 common genes common pathways GO:0016032| viral reproduction CD80;GRB2;CD86 GO:0031295| T cell costimulation CD86;GRB2;CD80 GO:0046854| phosphatidylinositol phosphorylation GRB2;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade GRB2;CD86;CD80 26020:[DB01281 DB07002] DB01281|Abatacept CD80;CD86 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways 26021:[DB01281 DB01113] DB01281|Abatacept CD80;CD86 DB01113|Papaverine PDE4B;PDE10A common genes common pathways GO:0007165| signal transduction CD86;PDE4B;PDE10A 26022:[DB01281 DB07364] DB01281|Abatacept CD80;CD86 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways 26023:[DB01281 DB14072] DB01281|Abatacept CD80;CD86 DB14072|Reversin 121 ABCB1 common genes common pathways 26024:[DB01281 DB05758] DB01281|Abatacept CD80;CD86 DB05758|CYT007-TNFQb TNF common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNF;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;TNF GO:0006955| immune response CD86;TNF 26025:[DB01281 DB07081] DB01281|Abatacept CD80;CD86 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 26026:[DB01281 DB02681] DB01281|Abatacept CD80;CD86 DB02681|2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium CKS1B common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CKS1B;CD86 26027:[DB01281 DB00205] DB01281|Abatacept CD80;CD86 DB00205|Pyrimethamine DHFR;HEXB;CYP2C8;SLC47A1;SLC47A2 common genes common pathways 26028:[DB01281 DB06495] DB01281|Abatacept CD80;CD86 DB06495|Onercept TNF common genes common pathways GO:0006955| immune response CD86;TNF GO:0051897| positive regulation of protein kinase B signaling cascade CD80;TNF;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;TNF 26029:[DB01281 DB01897] DB01281|Abatacept CD80;CD86 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways GO:0007165| signal transduction CD86;HPGDS 26030:[DB01281 DB11471] DB01281|Abatacept CD80;CD86 DB11471|Tilmicosin CYP3A4 common genes common pathways 26031:[DB01281 DB08067] DB01281|Abatacept CD80;CD86 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways GO:0035556| intracellular signal transduction CD80;JAK2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation JAK2;CD80 GO:0007165| signal transduction CD86;JAK2 GO:0008284| positive regulation of cell proliferation JAK2;CD86 GO:0002250| adaptive immune response JAK2;CD86 GO:0002376| immune system process JAK2;CD86 26032:[DB01281 DB11278] DB01281|Abatacept CD80;CD86 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;CD86;ADRA2A GO:0007165| signal transduction ADRA1D;CD86;ADRB3;ADRA2A;ADRB1;ADRA1A;ADRA2B;ADRB2;ADRA2C;ADRA1B GO:0035556| intracellular signal transduction ADRA1A;ADRA1B;CD80 26033:[DB01281 DB02342] DB01281|Abatacept CD80;CD86 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;HIF1A GO:0007165| signal transduction CD86;HIF1A 26034:[DB01281 DB14502] DB01281|Abatacept CD80;CD86 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction CD86;CD80;SLC20A2 GO:0007165| signal transduction CD86;SLC20A1 GO:0046718| entry of virus into host cell CD86;CD80;SLC20A2 26035:[DB01281 DB02417] DB01281|Abatacept CD80;CD86 DB02417|2,4,6-Tribromophenol TTR common genes common pathways 26036:[DB01281 DB14013] DB01281|Abatacept CD80;CD86 DB14013|SR-9009 NR1D1;NR1D2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;NR1D1;NR1D2;CD80 26037:[DB01281 DB07410] DB01281|Abatacept CD80;CD86 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways 26038:[DB01281 DB03542] DB01281|Abatacept CD80;CD86 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation IMPA1;CD86;CD80 GO:0007165| signal transduction CD86;IMPA1 26039:[DB01281 DB00507] DB01281|Abatacept CD80;CD86 DB00507|Nitazoxanide SLC19A1 common genes common pathways 26040:[DB01281 DB07776] DB01281|Abatacept CD80;CD86 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESRRA;ESRRB;CD86;CD80 26041:[DB01281 DB06689] DB01281|Abatacept CD80;CD86 DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways 26042:[DB01281 DB00922] DB01281|Abatacept CD80;CD86 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0007165| signal transduction CD86;PDE3A 26043:[DB01281 DB01176] DB01281|Abatacept CD80;CD86 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0007165| signal transduction HRH1;CD86 26044:[DB01281 DB09328] DB01281|Abatacept CD80;CD86 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways 26045:[DB01281 DB03597] DB01281|Abatacept CD80;CD86 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways GO:0007165| signal transduction PDE5A;PDE9A;CD86 26046:[DB01281 DB04857] DB01281|Abatacept CD80;CD86 DB04857|Brasofensine DRD2 common genes common pathways GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction DRD2;CD86 26047:[DB01281 DB02661] DB01281|Abatacept CD80;CD86 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways 26048:[DB01281 DB08229] DB01281|Abatacept CD80;CD86 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways GO:0035556| intracellular signal transduction CASP3;CD80 26049:[DB01281 DB02079] DB01281|Abatacept CD80;CD86 DB02079|Aminooxyacetic acid AGXT common genes common pathways 26050:[DB01281 DB05524] DB01281|Abatacept CD80;CD86 DB05524|Pelitinib EGFR common genes common pathways GO:0035556| intracellular signal transduction EGFR;CD80 GO:0007165| signal transduction EGFR;CD86 GO:0046718| entry of virus into host cell CD80;CD86;EGFR GO:0008284| positive regulation of cell proliferation CD86;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CD86;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;EGFR 26051:[DB01281 DB11155] DB01281|Abatacept CD80;CD86 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways 26052:[DB01281 DB00348] DB01281|Abatacept CD80;CD86 DB00348|Nitisinone HPD common genes common pathways 26053:[DB01281 DB11644] DB01281|Abatacept CD80;CD86 DB11644|Tafamidis TTR common genes common pathways 26054:[DB01281 DB03217] DB01281|Abatacept CD80;CD86 DB03217|DPI59 SRC common genes common pathways GO:0007165| signal transduction CD86;SRC GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction CD80;SRC;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80;CD86 26055:[DB01281 DB11751] DB01281|Abatacept CD80;CD86 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways 26056:[DB01281 DB02076] DB01281|Abatacept CD80;CD86 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways 26057:[DB01281 DB08373] DB01281|Abatacept CD80;CD86 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways GO:0007165| signal transduction CD86;SCGB1A1 26058:[DB01281 DB04911] DB01281|Abatacept CD80;CD86 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways 26059:[DB01281 DB01048] DB01281|Abatacept CD80;CD86 DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0016032| viral reproduction CD86;HLA-B;CD80 GO:0006955| immune response CD86;HLA-B GO:0002376| immune system process CD86;HLA-B 26060:[DB01281 DB01338] DB01281|Abatacept CD80;CD86 DB01338|Pipecuronium CHRNA2;CHRM2;CHRM3;BCHE common genes common pathways GO:0007165| signal transduction CHRM3;CD86;CHRM2;CHRNA2 26061:[DB01281 DB04512] DB01281|Abatacept CD80;CD86 DB04512|2-Isobutyl-3-Methoxypyrazine LCN9 common genes common pathways 26062:[DB01281 DB06475] DB01281|Abatacept CD80;CD86 DB06475|Ruplizumab CD40LG common genes common pathways GO:0006955| immune response CD86;CD40LG GO:0031295| T cell costimulation CD80;CD40LG;CD86 26063:[DB01281 DB04659] DB01281|Abatacept CD80;CD86 DB04659|(1S,2S,3R,4S,5S)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 26064:[DB01281 DB04912] DB01281|Abatacept CD80;CD86 DB04912|Stannsoporfin HMOX1;HMOX2 common genes common pathways GO:0035556| intracellular signal transduction HMOX1;CD80 26065:[DB01281 DB11090] DB01281|Abatacept CD80;CD86 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 26066:[DB01281 DB03642] DB01281|Abatacept CD80;CD86 DB03642|Benzofuran-2-Carboxylic Acid {(S)-3-Methyl-1-[3-Oxo-1-(Pyridin-2-Ylsulfonyl)Azepan-4-Ylcarbamoyl]Butyl}Amide CTSK common genes common pathways 26067:[DB01281 DB00670] DB01281|Abatacept CD80;CD86 DB00670|Pirenzepine CHRM1 common genes common pathways GO:0007165| signal transduction CD86;CHRM1 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 26068:[DB01281 DB04878] DB01281|Abatacept CD80;CD86 DB04878|Voglibose MGAM common genes common pathways 26069:[DB01281 DB00113] DB01281|Abatacept CD80;CD86 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways 26070:[DB01281 DB11132] DB01281|Abatacept CD80;CD86 DB11132|Silicon dioxide MARCO common genes common pathways GO:0002376| immune system process CD86;MARCO 26071:[DB01281 DB00311] DB01281|Abatacept CD80;CD86 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways 26072:[DB01281 DB00308] DB01281|Abatacept CD80;CD86 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways 26073:[DB01281 DB02048] DB01281|Abatacept CD80;CD86 DB02048|1,2,4-Triazole-Carboxamidine NOS3 common genes common pathways 26074:[DB01281 DB09237] DB01281|Abatacept CD80;CD86 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways 26075:[DB01281 DB04368] DB01281|Abatacept CD80;CD86 DB04368|Bb-3497 def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation PDF;CD86 26076:[DB01281 DB03273] DB01281|Abatacept CD80;CD86 DB03273|3'-Oxo-Adenosine AHCY common genes common pathways 26077:[DB01281 DB04214] DB01281|Abatacept CD80;CD86 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 26078:[DB01281 DB03078] DB01281|Abatacept CD80;CD86 DB03078|PASBN SRC common genes common pathways GO:0007165| signal transduction CD86;SRC GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction CD86;CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 26079:[DB01281 DB05382] DB01281|Abatacept CD80;CD86 DB05382|Iodine MT-ND5 common genes common pathways 26080:[DB01281 DB02490] DB01281|Abatacept CD80;CD86 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 26081:[DB01281 DB02106] DB01281|Abatacept CD80;CD86 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways 26082:[DB01281 DB07702] DB01281|Abatacept CD80;CD86 DB07702|17alpha-Estriol NCOA5;ESR2 common genes common pathways GO:0007165| signal transduction CD86;ESR2 GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;CD80 26083:[DB01281 DB03539] DB01281|Abatacept CD80;CD86 DB03539|2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose CHIT1 common genes common pathways GO:0006955| immune response CHIT1;CD86 26084:[DB01281 DB02730] DB01281|Abatacept CD80;CD86 DB02730|4-Methylthio-Alpha-D-Mannose AMY2B common genes common pathways 26085:[DB01281 DB04348] DB01281|Abatacept CD80;CD86 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0002376| immune system process CD86;NR1H4 GO:0007165| signal transduction CD86;NR1H4 GO:0046718| entry of virus into host cell CD86;SLC10A1;CD80 GO:0016032| viral reproduction SLC10A1;CD86;CD80 26086:[DB01281 DB00463] DB01281|Abatacept CD80;CD86 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction CHRNA7;GABRB3;GRIA2;CHRNA4;GABRA6;GABRB1;GABRQ;GABRE;CD86;GABRP;GABRD;GABRA5 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 26087:[DB01281 DB00680] DB01281|Abatacept CD80;CD86 DB00680|Moricizine SCN5A common genes common pathways 26088:[DB01281 DB08035] DB01281|Abatacept CD80;CD86 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 26089:[DB01281 DB03338] DB01281|Abatacept CD80;CD86 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways GO:0008284| positive regulation of cell proliferation PPARD;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARD;CD80 26090:[DB01281 DB00579] DB01281|Abatacept CD80;CD86 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways 26091:[DB01281 DB07354] DB01281|Abatacept CD80;CD86 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways GO:0016032| viral reproduction CD86;CD80;TOP1 26092:[DB01281 DB04895] DB01281|Abatacept CD80;CD86 DB04895|Pegaptanib NRP1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;NRP1 GO:0007165| signal transduction CD86;NRP1 26093:[DB01281 DB14581] DB01281|Abatacept CD80;CD86 DB14581|CPI-1205 EZH2 common genes common pathways 26094:[DB01281 DB14499] DB01281|Abatacept CD80;CD86 DB14499|Potassium sulfate ATP1A1 common genes common pathways 26095:[DB01281 DB06695] DB01281|Abatacept CD80;CD86 DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;F2 26096:[DB01281 DB04661] DB01281|Abatacept CD80;CD86 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways GO:0016032| viral reproduction CD80;CD86;CD1D GO:0002376| immune system process CD1D;CD86 26097:[DB01281 DB02343] DB01281|Abatacept CD80;CD86 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways 26098:[DB01281 DB06990] DB01281|Abatacept CD80;CD86 DB06990|4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID UNG common genes common pathways GO:0016032| viral reproduction CD86;UNG;CD80 26099:[DB01281 DB08819] DB01281|Abatacept CD80;CD86 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;PTGFR;CD86 GO:0007165| signal transduction CD86;PTGFR 26100:[DB01281 DB00627] DB01281|Abatacept CD80;CD86 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0007165| signal transduction HCAR3;CD86;HCAR2 26101:[DB01281 DB00050] DB01281|Abatacept CD80;CD86 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways GO:0007165| signal transduction LHCGR;CD86;GNRHR 26102:[DB01281 DB06732] DB01281|Abatacept CD80;CD86 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESRRA;AHR;ESR1;CD80 GO:0007165| signal transduction NR2F1;ESR1;CD86 26103:[DB01281 DB00341] DB01281|Abatacept CD80;CD86 DB00341|Cetirizine HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 26104:[DB01281 DB05983] DB01281|Abatacept CD80;CD86 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0016032| viral reproduction NFKBIA;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;NFKBIA;CD86 26105:[DB01281 DB09336] DB01281|Abatacept CD80;CD86 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways GO:0008284| positive regulation of cell proliferation EPCAM;CD86 26106:[DB01281 DB09532] DB01281|Abatacept CD80;CD86 DB09532|Secretin human SCTR common genes common pathways GO:0007165| signal transduction SCTR;CD86 26107:[DB01281 DB04100] DB01281|Abatacept CD80;CD86 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways 26108:[DB01281 DB03041] DB01281|Abatacept CD80;CD86 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 26109:[DB01281 DB03556] DB01281|Abatacept CD80;CD86 DB03556|2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 CBR1;CBR1 common genes common pathways 26110:[DB01281 DB00126] DB01281|Abatacept CD80;CD86 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways 26111:[DB01281 DB03442] DB01281|Abatacept CD80;CD86 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways 26112:[DB01281 DB09413] DB01281|Abatacept CD80;CD86 DB09413|Monopotassium phosphate ALPI common genes common pathways 26113:[DB01281 DB06360] DB01281|Abatacept CD80;CD86 DB06360|Lucatumumab CD40 common genes common pathways GO:0002376| immune system process CD86;CD40 GO:0006955| immune response CD40;CD86 26114:[DB01281 DB07122] DB01281|Abatacept CD80;CD86 DB07122|1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 26115:[DB01281 DB00035] DB01281|Abatacept CD80;CD86 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0007165| signal transduction AVPR1A;AVPR2;CD86;AVPR1B GO:0008284| positive regulation of cell proliferation AVPR1A;PTGS2;CD86;AVPR2 26116:[DB01281 DB02745] DB01281|Abatacept CD80;CD86 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 26117:[DB01281 DB04059] DB01281|Abatacept CD80;CD86 DB04059|8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 26118:[DB01281 DB11660] DB01281|Abatacept CD80;CD86 DB11660|Latanoprostene Bunod PTGFR;SLCO2B1 common genes common pathways GO:0007165| signal transduction CD86;PTGFR GO:0008284| positive regulation of cell proliferation PTGFR;CD86 26119:[DB01281 DB00669] DB01281|Abatacept CD80;CD86 DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;CD86 GO:0007165| signal transduction HTR1D;HTR1A;HTR1B;CD86;HTR1F 26120:[DB01281 DB09217] DB01281|Abatacept CD80;CD86 DB09217|Firocoxib PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 26121:[DB01281 DB00430] DB01281|Abatacept CD80;CD86 DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways 26122:[DB01281 DB05017] DB01281|Abatacept CD80;CD86 DB05017|YSIL6 TNF;IL6 common genes common pathways GO:0006955| immune response TNF;IL6;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;TNF;CD86;IL6 GO:0008284| positive regulation of cell proliferation CD86;IL6 26123:[DB01281 DB03506] DB01281|Abatacept CD80;CD86 DB03506|9-Deazaadenine APRT common genes common pathways 26124:[DB01281 DB03455] DB01281|Abatacept CD80;CD86 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways GO:0006955| immune response CD86;IL2 GO:0002376| immune system process CD86;IL2 GO:0002250| adaptive immune response CD86;IL2 GO:0008284| positive regulation of cell proliferation IL2;CD86 26125:[DB01281 DB12119] DB01281|Abatacept CD80;CD86 DB12119|Gevokizumab IL1B common genes common pathways GO:0008284| positive regulation of cell proliferation IL1B;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;IL1B;CD80 GO:0045086| positive regulation of interleukin-2 biosynthetic process IL1B;CD86;CD80 GO:0006955| immune response IL1B;CD86 GO:0007165| signal transduction CD86;IL1B 26126:[DB01281 DB07617] DB01281|Abatacept CD80;CD86 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways 26127:[DB01281 DB13751] DB01281|Abatacept CD80;CD86 DB13751|Glycyrrhizic acid HSD11B1;TNF;CASP3;NFKB2;NFKB1;LPL;AKR1C4;AKR1C3;AKR1C2;ALB;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AKR1C2;AKR1C3 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;AKR1C3;CD86;AKR1C2;TNF GO:0045893| positive regulation of transcription, DNA-dependent CD80;NFKB1;TNF;CD86 GO:0007165| signal transduction CD86;NFKB2;NFKB1 GO:0035556| intracellular signal transduction CASP3;CD80 GO:0006955| immune response CD86;TNF 26128:[DB01281 DB03711] DB01281|Abatacept CD80;CD86 DB03711|6-Hydroxy-6-Methyl-Heptan-3-One LCN9 common genes common pathways 26129:[DB01281 DB02587] DB01281|Abatacept CD80;CD86 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes common pathways GO:0035556| intracellular signal transduction ADCY2;ADCY5;CD80 GO:0007165| signal transduction CD86;ADCY2;GNAS 26130:[DB01281 DB08049] DB01281|Abatacept CD80;CD86 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways 26131:[DB01281 DB11198] DB01281|Abatacept CD80;CD86 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways 26132:[DB01281 DB03040] DB01281|Abatacept CD80;CD86 DB03040|Nitrilotriacetic Acid LTF common genes common pathways GO:0002376| immune system process LTF;CD86 26133:[DB01281 DB00545] DB01281|Abatacept CD80;CD86 DB00545|Pyridostigmine ACHE;BCHE;ALB;CYP3A4 common genes common pathways 26134:[DB01281 DB01330] DB01281|Abatacept CD80;CD86 DB01330|Cefotetan ALB common genes common pathways 26135:[DB01281 DB06549] DB01281|Abatacept CD80;CD86 DB06549|Labradimil BDKRB2 common genes common pathways GO:0007165| signal transduction CD86;BDKRB2 26136:[DB01281 DB01043] DB01281|Abatacept CD80;CD86 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;CD86 GO:0007165| signal transduction CD86;DRD2;HTR3A;CHRNA7 GO:0035556| intracellular signal transduction DRD2;CD80 26137:[DB01281 DB09472] DB01281|Abatacept CD80;CD86 DB09472|Sodium sulfate CA2;CA1 common genes common pathways 26138:[DB01281 DB09194] DB01281|Abatacept CD80;CD86 DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0035556| intracellular signal transduction CD80;ADRA1B;DRD2;ADRA1A GO:0007165| signal transduction ADRA1D;CHRM3;ADRA2A;HTR2C;CD86;DRD2;ADRA1A;CHRM4;CHRM1;ADRA2C;CHRM2;ADRA2B;HTR2A;CHRM5;ADRA1B GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0008284| positive regulation of cell proliferation CHRM1;HTR2A;ADRA1D;ADRA2A;CD86 26139:[DB01281 DB00968] DB01281|Abatacept CD80;CD86 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;CD86 GO:0007165| signal transduction ADRA2A;CD86 26140:[DB01281 DB12163] DB01281|Abatacept CD80;CD86 DB12163|Sarpogrelate HTR2C;HTR2A common genes common pathways GO:0007165| signal transduction HTR2C;CD86;HTR2A GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0008284| positive regulation of cell proliferation CD86;HTR2A 26141:[DB01281 DB02405] DB01281|Abatacept CD80;CD86 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways 26142:[DB01281 DB07901] DB01281|Abatacept CD80;CD86 DB07901|5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE METAP1 common genes common pathways 26143:[DB01281 DB02010] DB01281|Abatacept CD80;CD86 DB02010|Staurosporine LCK;PIM1;ITK;SYK;MAPKAPK2;GSK3B;CSK;CDK2;PIK3CG;PDPK1;PRKCQ;ZAP70;CHRM1;ABCB1 common genes common pathways GO:0016032| viral reproduction SYK;LCK;CD86;CD80 GO:0006955| immune response CD86;ZAP70 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SYK GO:0035556| intracellular signal transduction CD80;ITK;GSK3B;PDPK1;SYK;ZAP70;PRKCQ GO:0007165| signal transduction CD86;CHRM1;ITK GO:0045893| positive regulation of transcription, DNA-dependent CD80;CDK2;CD86 GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process CD80;SYK GO:0002250| adaptive immune response ZAP70;PIK3CG;SYK;CSK;CD86;ITK GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CG;LCK;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;CDK2;CHRM1 GO:0045086| positive regulation of interleukin-2 biosynthetic process CD80;PRKCQ;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;PIK3CG;CD86;LCK GO:0031295| T cell costimulation PDPK1;LCK;CSK;CD86;CD80 GO:0002376| immune system process ZAP70;PIK3CG;SYK;CSK;CD86;PRKCQ;ITK 26144:[DB01281 DB09035] DB01281|Abatacept CD80;CD86 DB09035|Nivolumab PDCD1 common genes common pathways GO:0031295| T cell costimulation PDCD1;CD80;CD86 GO:0002376| immune system process CD86;PDCD1 GO:0007165| signal transduction CD86;PDCD1 26145:[DB01281 DB03028] DB01281|Abatacept CD80;CD86 DB03028|1h-Benoximidazole-2-Carboxylic Acid CTSD common genes common pathways 26146:[DB01281 DB12159] DB01281|Abatacept CD80;CD86 DB12159|Dupilumab IL4R common genes common pathways GO:0006955| immune response CD86;IL4R GO:0007165| signal transduction IL4R;CD86 GO:0002376| immune system process IL4R;CD86 GO:0045630| positive regulation of T-helper 2 cell differentiation IL4R;CD86 26147:[DB01281 DB08770] DB01281|Abatacept CD80;CD86 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways GO:0007165| signal transduction ADORA2A;CD86 26148:[DB01281 DB01107] DB01281|Abatacept CD80;CD86 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRP;GABRD;GABRA5;CD86;GABRA6;GABRQ;GABRB1;GABRE;GABRB3 26149:[DB01281 DB02900] DB01281|Abatacept CD80;CD86 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways GO:0007165| signal transduction M6PR;CD86;IGF2R 26150:[DB01281 DB07498] DB01281|Abatacept CD80;CD86 DB07498|4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID AKR1B1 common genes common pathways 26151:[DB01281 DB00424] DB01281|Abatacept CD80;CD86 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007165| signal transduction CHRM2;CHRM1;CD86;CHRM4;CHRM3 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 26152:[DB01281 DB01946] DB01281|Abatacept CD80;CD86 DB01946|3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione PDPK1;DMPK common genes common pathways GO:0031295| T cell costimulation CD80;CD86;PDPK1 GO:0035556| intracellular signal transduction PDPK1;CD80 26153:[DB01281 DB09535] DB01281|Abatacept CD80;CD86 DB09535|Octocrylene ESR1;ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR2;CD80;ESR1 GO:0007165| signal transduction ESR1;CD86;ESR2 26154:[DB01281 DB04021] DB01281|Abatacept CD80;CD86 DB04021|MF268 ACHE common genes common pathways 26155:[DB01281 DB09045] DB01281|Abatacept CD80;CD86 DB09045|Dulaglutide GLP1R common genes common pathways GO:0007165| signal transduction CD86;GLP1R 26156:[DB01281 DB06307] DB01281|Abatacept CD80;CD86 DB06307|Apoptone BCL2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BCL2 26157:[DB01281 DB09105] DB01281|Abatacept CD80;CD86 DB09105|Asfotase Alfa S1PR1 common genes common pathways GO:0008284| positive regulation of cell proliferation S1PR1;CD86 GO:0007165| signal transduction S1PR1;CD86 26158:[DB01281 DB09299] DB01281|Abatacept CD80;CD86 DB09299|Tenofovir alafenamide pol;ABCB1 common genes common pathways 26159:[DB01281 DB06325] DB01281|Abatacept CD80;CD86 DB06325|Pegpleranib PDGFB common genes common pathways GO:0008284| positive regulation of cell proliferation PDGFB;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;PDGFB;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;PDGFB;CD80 GO:0046854| phosphatidylinositol phosphorylation CD86;PDGFB;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation PDGFB;CD80 26160:[DB01281 DB07286] DB01281|Abatacept CD80;CD86 DB07286|BMS-564929 AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR GO:0008284| positive regulation of cell proliferation CD86;AR 26161:[DB01281 DB04620] DB01281|Abatacept CD80;CD86 DB04620|Cycloleucine GRIN1 common genes common pathways 26162:[DB01281 DB01332] DB01281|Abatacept CD80;CD86 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways 26163:[DB01281 DB07344] DB01281|Abatacept CD80;CD86 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways 26164:[DB01281 DB03923] DB01281|Abatacept CD80;CD86 DB03923|Feruloyl Coenzyme A COMTD1 common genes common pathways 26165:[DB01281 DB07394] DB01281|Abatacept CD80;CD86 DB07394|AUROVERTIN B ATP5B common genes common pathways 26166:[DB01281 DB05192] DB01281|Abatacept CD80;CD86 DB05192|MB07811 THRB common genes common pathways 26167:[DB01281 DB09341] DB01281|Abatacept CD80;CD86 DB09341|Dextrose, unspecified form HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1 common genes common pathways 26168:[DB01281 DB04519] DB01281|Abatacept CD80;CD86 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARA;CD86 26169:[DB01281 DB03664] DB01281|Abatacept CD80;CD86 DB03664|UP5 CMPK1 common genes common pathways 26170:[DB01281 DB08088] DB01281|Abatacept CD80;CD86 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0007165| signal transduction AR;CD86 26171:[DB01281 DB08740] DB01281|Abatacept CD80;CD86 DB08740|CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE CTSD common genes common pathways 26172:[DB01281 DB00191] DB01281|Abatacept CD80;CD86 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways 26173:[DB01281 DB06650] DB01281|Abatacept CD80;CD86 DB06650|Ofatumumab MS4A1 common genes common pathways 26174:[DB01281 DB00371] DB01281|Abatacept CD80;CD86 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0007165| signal transduction GABRP;GABRD;GABRA5;CD86;GABRA6;GABRB1;GABRQ;GABRE;GABRB3 26175:[DB01281 DB03456] DB01281|Abatacept CD80;CD86 DB03456|N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide CTSK common genes common pathways 26176:[DB01281 DB04409] DB01281|Abatacept CD80;CD86 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;FGF1;CD80 GO:0008284| positive regulation of cell proliferation FGF1;CD86 GO:0046854| phosphatidylinositol phosphorylation FGF1;CD80;CD86 GO:0007165| signal transduction FGF1;CD86 26177:[DB01281 DB02509] DB01281|Abatacept CD80;CD86 DB02509|Farnesol MAOB;NR1H4;MAOB common genes common pathways GO:0007165| signal transduction CD86;NR1H4 GO:0002376| immune system process NR1H4;CD86 26178:[DB01281 DB08560] DB01281|Abatacept CD80;CD86 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD80 26179:[DB01281 DB07917] DB01281|Abatacept CD80;CD86 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways GO:0007165| signal transduction CD86;HPGDS 26180:[DB01281 DB03384] DB01281|Abatacept CD80;CD86 DB03384|Fica CASP7 common genes common pathways 26181:[DB01281 DB07630] DB01281|Abatacept CD80;CD86 DB07630|N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 26182:[DB01281 DB00283] DB01281|Abatacept CD80;CD86 DB00283|Clemastine HRH1;CYP2D6 common genes common pathways GO:0007165| signal transduction HRH1;CD86 26183:[DB01281 DB00931] DB01281|Abatacept CD80;CD86 DB00931|Metacycline ALB common genes common pathways 26184:[DB01281 DB05233] DB01281|Abatacept CD80;CD86 DB05233|AP1081 ESR1 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 26185:[DB01281 DB00903] DB01281|Abatacept CD80;CD86 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent LEF1;CD80;CD86 GO:0008284| positive regulation of cell proliferation LEF1;CD86 26186:[DB01281 DB07789] DB01281|Abatacept CD80;CD86 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways 26187:[DB01281 DB06945] DB01281|Abatacept CD80;CD86 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways 26188:[DB01281 DB00856] DB01281|Abatacept CD80;CD86 DB00856|Chlorphenesin CYP2B;CYP19A1;CYP3A4;XDH;PTGS2;BCHE common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26189:[DB01281 DB02328] DB01281|Abatacept CD80;CD86 DB02328|2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid CTH common genes common pathways 26190:[DB01281 DB04491] DB01281|Abatacept CD80;CD86 DB04491|Diisopropylphosphono Group CFB;DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0002376| immune system process CD86;CFB GO:0031295| T cell costimulation CD86;DPP4;CD80 26191:[DB01281 DB01089] DB01281|Abatacept CD80;CD86 DB01089|Deserpidine SLC18A2 common genes common pathways 26192:[DB01281 DB13166] DB01281|Abatacept CD80;CD86 DB13166|Zofenopril ACE common genes common pathways 26193:[DB01281 DB00861] DB01281|Abatacept CD80;CD86 DB00861|Diflunisal PTGS2;PTGS1;UGT1A8;UGT1A9;TTR;ALB;SLC22A6 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 26194:[DB01281 DB00995] DB01281|Abatacept CD80;CD86 DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent IKBKB;CD80;CD86 26195:[DB01281 DB08930] DB01281|Abatacept CD80;CD86 DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes common pathways 26196:[DB01281 DB11858] DB01281|Abatacept CD80;CD86 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways GO:0006955| immune response CD86;CYSLTR2 GO:0007165| signal transduction CYSLTR2;CD86;CYSLTR1 26197:[DB01281 DB07257] DB01281|Abatacept CD80;CD86 DB07257|4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione WEE1 common genes common pathways 26198:[DB01281 DB09070] DB01281|Abatacept CD80;CD86 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 26199:[DB01281 DB09479] DB01281|Abatacept CD80;CD86 DB09479|Rubidium Rb-82 FXYD2;ATP1A1;ATP1B1;ATP1B2;ATP1B3;ATP1A4;ATP1A2;ATP1A3 common genes common pathways 26200:[DB01281 DB02462] DB01281|Abatacept CD80;CD86 DB02462|Thiocoumarin NOS2 common genes common pathways 26201:[DB01281 DB02395] DB01281|Abatacept CD80;CD86 DB02395|3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol NQO1 common genes common pathways 26202:[DB01281 DB00964] DB01281|Abatacept CD80;CD86 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways GO:0035556| intracellular signal transduction CD80;ADRA1A GO:0007165| signal transduction ADRA1A;CD86;ADRA2A;ADRA2B GO:0008284| positive regulation of cell proliferation CD86;ADRA2A 26203:[DB01281 DB00487] DB01281|Abatacept CD80;CD86 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways 26204:[DB01281 DB07154] DB01281|Abatacept CD80;CD86 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0046718| entry of virus into host cell DPP4;CD86;CD80 26205:[DB01281 DB13881] DB01281|Abatacept CD80;CD86 DB13881|Tisagenlecleucel CD19 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD19;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;CD19;CD86 26206:[DB01281 DB04233] DB01281|Abatacept CD80;CD86 DB04233|(Hydroxyethyloxy)Tri(Ethyloxy)Octane CLPS;PNLIP;RHO common genes common pathways GO:0007165| signal transduction CD86;RHO 26207:[DB01281 DB03703] DB01281|Abatacept CD80;CD86 DB03703|Cyclohexanol ADH1B common genes common pathways 26208:[DB01281 DB09203] DB01281|Abatacept CD80;CD86 DB09203|Synephrine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ADRA1D GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0007165| signal transduction ADRA1B;ADRA1D;ADRA1A;CD86 26209:[DB01281 DB04852] DB01281|Abatacept CD80;CD86 DB04852|Implitapide MTTP common genes common pathways 26210:[DB01281 DB05920] DB01281|Abatacept CD80;CD86 DB05920|RTA 744 TOP2A common genes common pathways 26211:[DB01281 DB08163] DB01281|Abatacept CD80;CD86 DB08163|5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine AMD1 common genes common pathways 26212:[DB01281 DB03894] DB01281|Abatacept CD80;CD86 DB03894|N-Propargyl-1(S)-Aminoindan MAOB;MAOB common genes common pathways 26213:[DB01281 DB05938] DB01281|Abatacept CD80;CD86 DB05938|Edonerpic APP common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade APP;CD86;CD80 26214:[DB01281 DB12610] DB01281|Abatacept CD80;CD86 DB12610|Ebselen EPHX2 common genes common pathways 26215:[DB01281 DB07063] DB01281|Abatacept CD80;CD86 DB07063|{3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID AKR1B1 common genes common pathways 26216:[DB01281 DB11397] DB01281|Abatacept CD80;CD86 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways 26217:[DB01281 DB00600] DB01281|Abatacept CD80;CD86 DB00600|Monobenzone TYR common genes common pathways 26218:[DB01281 DB03889] DB01281|Abatacept CD80;CD86 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 26219:[DB01281 DB01831] DB01281|Abatacept CD80;CD86 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways 26220:[DB01281 DB14527] DB01281|Abatacept CD80;CD86 DB14527|Chromic nitrate CYB5A;TF common genes common pathways 26221:[DB01281 DB02637] DB01281|Abatacept CD80;CD86 DB02637|Oxaloacetate Ion CS;mdh;SPR common genes common pathways 26222:[DB01281 DB08435] DB01281|Abatacept CD80;CD86 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;PPARG 26223:[DB01281 DB07580] DB01281|Abatacept CD80;CD86 DB07580|BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE APCS common genes common pathways 26224:[DB01281 DB00104] DB01281|Abatacept CD80;CD86 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;SSTR1;SSTR2;SSTR5 26225:[DB01281 DB06410] DB01281|Abatacept CD80;CD86 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0007165| signal transduction CD86;VDR 26226:[DB01281 DB01064] DB01281|Abatacept CD80;CD86 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade PIK3R2;PIK3R1;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent MAPK1;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;MAPK1 GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;PIK3R1;PIK3R2 GO:0031295| T cell costimulation PIK3R1;CD86;CD80 GO:0016032| viral reproduction PIK3R1;CD86;MAPK1;CD80 GO:0035556| intracellular signal transduction CD80;MAPK1 GO:0007165| signal transduction ADRB2;CD86;ADRB3;PIK3R1;ADRB1;PIK3R2;MAPK1 26227:[DB01281 DB03948] DB01281|Abatacept CD80;CD86 DB03948|6-Chloropurine Riboside, 5'-Monophosphate IMPDH1;IMPDH2 common genes common pathways 26228:[DB01281 DB06721] DB01281|Abatacept CD80;CD86 DB06721|Gimatecan SLCO1B1 common genes common pathways 26229:[DB01281 DB04853] DB01281|Abatacept CD80;CD86 DB04853|Binodenoson ADORA2A common genes common pathways GO:0007165| signal transduction ADORA2A;CD86 26230:[DB01281 DB01947] DB01281|Abatacept CD80;CD86 DB01947|RU78262 SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0002376| immune system process CD86;SRC GO:0035556| intracellular signal transduction CD80;SRC GO:0016032| viral reproduction CD80;SRC;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0007165| signal transduction CD86;SRC 26231:[DB01281 DB02515] DB01281|Abatacept CD80;CD86 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways 26232:[DB01281 DB03486] DB01281|Abatacept CD80;CD86 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways GO:0007165| signal transduction CD86;CANT1 26233:[DB01281 DB07747] DB01281|Abatacept CD80;CD86 DB07747|(3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 26234:[DB01281 DB14529] DB01281|Abatacept CD80;CD86 DB14529|Chromium nicotinate CYB5A;TF common genes common pathways 26235:[DB01281 DB01678] DB01281|Abatacept CD80;CD86 DB01678|RU84687 SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;SRC GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0031295| T cell costimulation SRC;CD80;CD86 GO:0002376| immune system process CD86;SRC GO:0016032| viral reproduction CD80;SRC;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0035556| intracellular signal transduction CD80;SRC GO:0007165| signal transduction SRC;CD86 26236:[DB01281 DB10772] DB01281|Abatacept CD80;CD86 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways GO:0008284| positive regulation of cell proliferation TGFB1;VEGFA;TGFBR2;FGF1;IFNG;FGFR2;EGFR;PDGFRA;IL6;IL1B;CD86 GO:0045893| positive regulation of transcription, DNA-dependent TGFB1;CD80;IL6;EGFR;CD86;IL1B;TNF GO:0002250| adaptive immune response CD86;IFNG GO:0051897| positive regulation of protein kinase B signaling cascade FGFR2;FGF1;TGFB1;CD80;CD86;PDGFRA;EGFR;TNF GO:0046854| phosphatidylinositol phosphorylation FGFR2;FGF1;CD80;CD86;PDGFRA;EGFR GO:0045086| positive regulation of interleukin-2 biosynthetic process CD80;IL1B;CD86 GO:0035556| intracellular signal transduction CD80;EGFR GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation TGFB1;CD80;VEGFA;IL6 GO:0006955| immune response TNF;IL6;IL1B;CD86;IFNG GO:0016032| viral reproduction CD86;PDGFRA;CD80 GO:0046718| entry of virus into host cell EGFR;CD86;CD80 GO:0007165| signal transduction EGFR;IL1B;CD86;FGF1 26237:[DB01281 DB02107] DB01281|Abatacept CD80;CD86 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 26238:[DB01281 DB08488] DB01281|Abatacept CD80;CD86 DB08488|4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 26239:[DB01281 DB07087] DB01281|Abatacept CD80;CD86 DB07087|4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 GO:0007165| signal transduction ESR1;CD86 26240:[DB01281 DB04256] DB01281|Abatacept CD80;CD86 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways GO:0007165| signal transduction CD86;GRM1 26241:[DB01281 DB06538] DB01281|Abatacept CD80;CD86 DB06538|Robalzotan HTR1A common genes common pathways GO:0007165| signal transduction HTR1A;CD86 GO:0008284| positive regulation of cell proliferation CD86;HTR1A 26242:[DB01281 DB08156] DB01281|Abatacept CD80;CD86 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways 26243:[DB01281 DB14002] DB01281|Abatacept CD80;CD86 DB14002|D-alpha-Tocopherol acetate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0035556| intracellular signal transduction PRKCB;CD80;DGKA;HMOX1;PRKCA GO:0007165| signal transduction CD86;NR1I2;PRKCB GO:0002250| adaptive immune response CD86;PRKCB GO:0045893| positive regulation of transcription, DNA-dependent CD80;SEC14L2;NR1I2;CD86 GO:0002376| immune system process CD86;PRKCB 26244:[DB01281 DB08190] DB01281|Abatacept CD80;CD86 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways 26245:[DB01281 DB08221] DB01281|Abatacept CD80;CD86 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;TEK GO:0007165| signal transduction TEK;CD86 GO:0035556| intracellular signal transduction CD80;TEK 26246:[DB01281 DB09280] DB01281|Abatacept CD80;CD86 DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways 26247:[DB01281 DB00633] DB01281|Abatacept CD80;CD86 DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;CD86 GO:0007165| signal transduction CD86;ADRA2A 26248:[DB01281 DB04578] DB01281|Abatacept CD80;CD86 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell DPP4;CD86;CD80 26249:[DB01281 DB01349] DB01281|Abatacept CD80;CD86 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways GO:0007165| signal transduction AGTR2;CD86;AGTR1 GO:0035556| intracellular signal transduction AGTR2;CD80 GO:0008284| positive regulation of cell proliferation AGTR2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;AGTR2 26250:[DB01281 DB11774] DB01281|Abatacept CD80;CD86 DB11774|Pazufloxacin CYP1A2 common genes common pathways 26251:[DB01281 DB04910] DB01281|Abatacept CD80;CD86 DB04910|Oxibendazole TUBB4B common genes common pathways 26252:[DB01281 DB08772] DB01281|Abatacept CD80;CD86 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways 26253:[DB01281 DB08222] DB01281|Abatacept CD80;CD86 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways 26254:[DB01281 DB01951] DB01281|Abatacept CD80;CD86 DB01951|Gpi-1046 FKBP1A common genes common pathways 26255:[DB01281 DB09154] DB01281|Abatacept CD80;CD86 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 26256:[DB01281 DB00140] DB01281|Abatacept CD80;CD86 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways 26257:[DB01281 DB01231] DB01281|Abatacept CD80;CD86 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways GO:0007165| signal transduction CHRM2;CHRM1;CHRM3;CD86 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 26258:[DB01281 DB00710] DB01281|Abatacept CD80;CD86 DB00710|Ibandronate FDPS common genes common pathways GO:0016032| viral reproduction CD86;FDPS;CD80 26259:[DB01281 DB00144] DB01281|Abatacept CD80;CD86 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0035556| intracellular signal transduction PRKCA;DGKD;DGKG;CD80 GO:0016032| viral reproduction CD80;SCARB1;CD86 GO:0007165| signal transduction DGKD;CD86;DGKG GO:0046718| entry of virus into host cell CD80;SCARB1;CD86 26260:[DB01281 DB00511] DB01281|Abatacept CD80;CD86 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways 26261:[DB01281 DB00917] DB01281|Abatacept CD80;CD86 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0007165| signal transduction CD86;PTGER4;PTGDR2;PTGER2;PTGER1;PTGER3 GO:0006955| immune response PTGDR2;PTGER4;CD86 26262:[DB01281 DB00331] DB01281|Abatacept CD80;CD86 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0007165| signal transduction PRKAB1;CD86 26263:[DB01281 DB08353] DB01281|Abatacept CD80;CD86 DB08353|2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 GO:0007165| signal transduction CSNK2A1;CD86 26264:[DB01281 DB03292] DB01281|Abatacept CD80;CD86 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways 26265:[DB01281 DB07700] DB01281|Abatacept CD80;CD86 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0008284| positive regulation of cell proliferation AKR1C3;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;AKR1C3 26266:[DB01281 DB01271] DB01281|Abatacept CD80;CD86 DB01271|Idursulfase PLIN3 common genes common pathways 26267:[DB01281 DB07680] DB01281|Abatacept CD80;CD86 DB07680|[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID CMA1 common genes common pathways 26268:[DB01281 DB04957] DB01281|Abatacept CD80;CD86 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways 26269:[DB01281 DB04919] DB01281|Abatacept CD80;CD86 DB04919|Alfimeprase FGA;FGB common genes common pathways GO:0007165| signal transduction FGB;FGA;CD86 GO:0002376| immune system process FGA;CD86;FGB GO:0002250| adaptive immune response CD86;FGA;FGB 26270:[DB01281 DB08885] DB01281|Abatacept CD80;CD86 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;VEGFA;PGF GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;VEGFB GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA;VEGFB GO:0007165| signal transduction PGF;CD86 26271:[DB01281 DB03832] DB01281|Abatacept CD80;CD86 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways 26272:[DB01281 DB02353] DB01281|Abatacept CD80;CD86 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways GO:0006955| immune response CCL5;CD86 26273:[DB01281 DB11760] DB01281|Abatacept CD80;CD86 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes common pathways 26274:[DB01281 DB08750] DB01281|Abatacept CD80;CD86 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways 26275:[DB01281 DB02691] DB01281|Abatacept CD80;CD86 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways 26276:[DB01281 DB01889] DB01281|Abatacept CD80;CD86 DB01889|16,17-Androstene-3-Ol NR1I3 common genes common pathways GO:0007165| signal transduction NR1I3;CD86 26277:[DB01281 DB00614] DB01281|Abatacept CD80;CD86 DB00614|Furazolidone MAOB;MAOA common genes common pathways 26278:[DB01281 DB01733] DB01281|Abatacept CD80;CD86 DB01733|L-Phospholactate PKM common genes common pathways 26279:[DB01281 DB01399] DB01281|Abatacept CD80;CD86 DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26280:[DB01281 DB05514] DB01281|Abatacept CD80;CD86 DB05514|Cobiprostone CLCN2 common genes common pathways 26281:[DB01281 DB07831] DB01281|Abatacept CD80;CD86 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ABL1 26282:[DB01281 DB07093] DB01281|Abatacept CD80;CD86 DB07093|{3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID AKR1B1 common genes common pathways 26283:[DB01281 DB01272] DB01281|Abatacept CD80;CD86 DB01272|Alglucosidase alfa M6PR common genes common pathways GO:0007165| signal transduction M6PR;CD86 26284:[DB01281 DB04794] DB01281|Abatacept CD80;CD86 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways 26285:[DB01281 DB00769] DB01281|Abatacept CD80;CD86 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;NR3C1 26286:[DB01281 DB07396] DB01281|Abatacept CD80;CD86 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways 26287:[DB01281 DB05796] DB01281|Abatacept CD80;CD86 DB05796|Daglutril MME common genes common pathways 26288:[DB01281 DB09140] DB01281|Abatacept CD80;CD86 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;NOX1 GO:0007165| signal transduction NOX1;CD86 26289:[DB01281 DB01237] DB01281|Abatacept CD80;CD86 DB01237|Bromodiphenhydramine HRH1;SLC22A6 common genes common pathways GO:0007165| signal transduction HRH1;CD86 26290:[DB01281 DB08259] DB01281|Abatacept CD80;CD86 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways 26291:[DB01281 DB01738] DB01281|Abatacept CD80;CD86 DB01738|Phosphorylcolamine PRKCB common genes common pathways GO:0002250| adaptive immune response PRKCB;CD86 GO:0002376| immune system process PRKCB;CD86 GO:0035556| intracellular signal transduction PRKCB;CD80 GO:0007165| signal transduction PRKCB;CD86 26292:[DB01281 DB03978] DB01281|Abatacept CD80;CD86 DB03978|Tyrosinal tyrS;YARS;YARS common genes common pathways GO:0007165| signal transduction CD86;YARS 26293:[DB01281 DB06814] DB01281|Abatacept CD80;CD86 DB06814|Protokylol ADRB2 common genes common pathways GO:0007165| signal transduction ADRB2;CD86 26294:[DB01281 DB07919] DB01281|Abatacept CD80;CD86 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways 26295:[DB01281 DB03945] DB01281|Abatacept CD80;CD86 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways 26296:[DB01281 DB09064] DB01281|Abatacept CD80;CD86 DB09064|Ciprofibrate PPARA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARA;CD80 26297:[DB01281 DB03451] DB01281|Abatacept CD80;CD86 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways GO:0007165| signal transduction CD86;VDR 26298:[DB01281 DB12118] DB01281|Abatacept CD80;CD86 DB12118|Sotatercept ACVR2A common genes common pathways 26299:[DB01281 DB02039] DB01281|Abatacept CD80;CD86 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways GO:0016032| viral reproduction CD86;KAT5;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;KAT5 26300:[DB01281 DB05234] DB01281|Abatacept CD80;CD86 DB05234|LGD2941 AR common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 26301:[DB01281 DB05542] DB01281|Abatacept CD80;CD86 DB05542|Naronapride HTR4 common genes common pathways GO:0007165| signal transduction CD86;HTR4 26302:[DB01281 DB04757] DB01281|Abatacept CD80;CD86 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0006955| immune response CD86;PNP 26303:[DB01281 DB03435] DB01281|Abatacept CD80;CD86 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways 26304:[DB01281 DB04244] DB01281|Abatacept CD80;CD86 DB04244|(2R)-2-(3-Biphenylyl)-N-{(2R)-2-hydroxy-3-[(2-pyridinylsulfonyl)amino]propyl}-4-methylpentanamide CTSK common genes common pathways 26305:[DB01281 DB08159] DB01281|Abatacept CD80;CD86 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways GO:0016032| viral reproduction CD86;TOP1;CD80 26306:[DB01281 DB08101] DB01281|Abatacept CD80;CD86 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways 26307:[DB01281 DB12688] DB01281|Abatacept CD80;CD86 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways 26308:[DB01281 DB02282] DB01281|Abatacept CD80;CD86 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 26309:[DB01281 DB11869] DB01281|Abatacept CD80;CD86 DB11869|Valspodar SLCO1B1;SLCO1B3 common genes common pathways 26310:[DB01281 DB06039] DB01281|Abatacept CD80;CD86 DB06039|PA-1050040 gag common genes common pathways 26311:[DB01281 DB02311] DB01281|Abatacept CD80;CD86 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways 26312:[DB01281 DB04069] DB01281|Abatacept CD80;CD86 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways GO:0035556| intracellular signal transduction DAPK1;CD80 GO:0007165| signal transduction DAPK1;CD86 26313:[DB01281 DB00178] DB01281|Abatacept CD80;CD86 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0007165| signal transduction BDKRB1;CD86 26314:[DB01281 DB01160] DB01281|Abatacept CD80;CD86 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways GO:0007165| signal transduction PTGFR;CD86;PTGIR GO:0008284| positive regulation of cell proliferation CD86;PTGFR 26315:[DB01281 DB13996] DB01281|Abatacept CD80;CD86 DB13996|Magnesium acetate ATP1A1 common genes common pathways 26316:[DB01281 DB09571] DB01281|Abatacept CD80;CD86 DB09571|Levmetamfetamine PNMT common genes common pathways 26317:[DB01281 DB00815] DB01281|Abatacept CD80;CD86 DB00815|Sodium lauryl sulfate ALB common genes common pathways 26318:[DB01281 DB03253] DB01281|Abatacept CD80;CD86 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD80;CD86;DPP4 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 26319:[DB01281 DB00925] DB01281|Abatacept CD80;CD86 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0007165| signal transduction ADRA2C;ADRB2;ADRA2B;ADRA1B;ADRA1D;ADRA2A;CD86;ADRA1A GO:0035556| intracellular signal transduction ADRA1A;ADRA1B;CD80 GO:0008284| positive regulation of cell proliferation ADRA1D;CD86;ADRA2A 26320:[DB01281 DB12418] DB01281|Abatacept CD80;CD86 DB12418|Saccharin CA3 common genes common pathways 26321:[DB01281 DB08162] DB01281|Abatacept CD80;CD86 DB08162|Fasudil PKIA;PRKACA;ROCK1;ROCK2 common genes common pathways GO:0007165| signal transduction ROCK1;CD86 GO:0035556| intracellular signal transduction ROCK2;ROCK1;CD80 26322:[DB01281 DB07837] DB01281|Abatacept CD80;CD86 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways GO:0035556| intracellular signal transduction SGK1;CD80 26323:[DB01281 DB01811] DB01281|Abatacept CD80;CD86 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways GO:0002376| immune system process CD86;LTF 26324:[DB01281 DB00449] DB01281|Abatacept CD80;CD86 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ADRA2A GO:0007165| signal transduction ADRA1A;ADRA2A;CD86;ADRB2 GO:0035556| intracellular signal transduction ADRA1A;CD80 26325:[DB01281 DB12061] DB01281|Abatacept CD80;CD86 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD3;DRD2;CD86;HTR1A;DRD4 GO:0008284| positive regulation of cell proliferation HTR1A;DRD3;CD86 26326:[DB01281 DB06215] DB01281|Abatacept CD80;CD86 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0006955| immune response CD86;FTH1 26327:[DB01281 DB01444] DB01281|Abatacept CD80;CD86 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes common pathways GO:0007165| signal transduction CD86;OPRM1;OPRD1 GO:0006955| immune response OPRD1;CD86 26328:[DB01281 DB05417] DB01281|Abatacept CD80;CD86 DB05417|GW 468816 GLRA1 common genes common pathways 26329:[DB01281 DB02338] DB01281|Abatacept CD80;CD86 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0007165| signal transduction TXNRD1;CD86 26330:[DB01281 DB01973] DB01281|Abatacept CD80;CD86 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 26331:[DB01281 DB09462] DB01281|Abatacept CD80;CD86 DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PPARD;TGFBR2 GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARD;CD80 GO:0007165| signal transduction HPGDS;ITPR1;CD86 26332:[DB01281 DB02508] DB01281|Abatacept CD80;CD86 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0016032| viral reproduction CD86;CD80;FDPS 26333:[DB01281 DB00319] DB01281|Abatacept CD80;CD86 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways 26334:[DB01281 DB02473] DB01281|Abatacept CD80;CD86 DB02473|6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 26335:[DB01281 DB08493] DB01281|Abatacept CD80;CD86 DB08493|5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID MMP7 common genes common pathways 26336:[DB01281 DB09340] DB01281|Abatacept CD80;CD86 DB09340|Tyropanoic acid GUSB common genes common pathways 26337:[DB01281 DB06248] DB01281|Abatacept CD80;CD86 DB06248|Amelubant LTB4R2;LTB4R common genes common pathways GO:0006955| immune response LTB4R;CD86 GO:0007165| signal transduction LTB4R;LTB4R2;CD86 26338:[DB01281 DB00716] DB01281|Abatacept CD80;CD86 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0006955| immune response CD86;CYSLTR2 GO:0007165| signal transduction FPR1;CYSLTR2;PTGDR;CYSLTR1;CD86;HSP90AA1 26339:[DB01281 DB04685] DB01281|Abatacept CD80;CD86 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways 26340:[DB01281 DB04072] DB01281|Abatacept CD80;CD86 DB04072|Alpha-Methylisocitric Acid ACO2 common genes common pathways 26341:[DB01281 DB00030] DB01281|Abatacept CD80;CD86 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0035556| intracellular signal transduction CD80;INSR GO:0006955| immune response IGF1R;CD86 GO:0016032| viral reproduction CD80;RB1;CD86;IDE GO:0046718| entry of virus into host cell CD80;IDE;CD86 GO:0007165| signal transduction IGF1R;CD86 GO:0008284| positive regulation of cell proliferation INSR;CD86;IGF1R GO:0045893| positive regulation of transcription, DNA-dependent RB1;CD80;CD86;INSR GO:0051897| positive regulation of protein kinase B signaling cascade CD86;INSR;CD80 26342:[DB01281 DB08482] DB01281|Abatacept CD80;CD86 DB08482|[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER MMP1 common genes common pathways GO:0016032| viral reproduction CD80;MMP1;CD86 26343:[DB01281 DB13967] DB01281|Abatacept CD80;CD86 DB13967|Patent Blue ALB common genes common pathways 26344:[DB01281 DB07696] DB01281|Abatacept CD80;CD86 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways GO:0035556| intracellular signal transduction CD80;CASP3 26345:[DB01281 DB13884] DB01281|Abatacept CD80;CD86 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;CD86;CD80 26346:[DB01281 DB00275] DB01281|Abatacept CD80;CD86 DB00275|Olmesartan AGTR1;ABCC2;SLCO1B3;SLCO1B1;ABCB11 common genes common pathways GO:0007165| signal transduction AGTR1;CD86 26347:[DB01281 DB03650] DB01281|Abatacept CD80;CD86 DB03650|(3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One PIM1 common genes common pathways 26348:[DB01281 DB11995] DB01281|Abatacept CD80;CD86 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways 26349:[DB01281 DB14600] DB01281|Abatacept CD80;CD86 DB14600|Edetate disodium anhydrous ADA;CYP1A2;PON3;CYP19A1 common genes common pathways 26350:[DB01281 DB06457] DB01281|Abatacept CD80;CD86 DB06457|Tecastemizole KCNH2 common genes common pathways 26351:[DB01281 DB05413] DB01281|Abatacept CD80;CD86 DB05413|Tifuvirtide SERPINA5 common genes common pathways 26352:[DB01281 DB07117] DB01281|Abatacept CD80;CD86 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 26353:[DB01281 DB06371] DB01281|Abatacept CD80;CD86 DB06371|Siplizumab CD2 common genes common pathways 26354:[DB01281 DB06602] DB01281|Abatacept CD80;CD86 DB06602|Reslizumab IL5 common genes common pathways GO:0006955| immune response CD86;IL5 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;IL5 GO:0008284| positive regulation of cell proliferation IL5;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;IL5 26355:[DB01281 DB04119] DB01281|Abatacept CD80;CD86 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways GO:0035556| intracellular signal transduction CAMK2A;CD80 26356:[DB01281 DB07930] DB01281|Abatacept CD80;CD86 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways 26357:[DB01281 DB11949] DB01281|Abatacept CD80;CD86 DB11949|Vestipitant TACR1 common genes common pathways GO:0007165| signal transduction CD86;TACR1 26358:[DB01281 DB07500] DB01281|Abatacept CD80;CD86 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways 26359:[DB01281 DB03195] DB01281|Abatacept CD80;CD86 DB03195|Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways 26360:[DB01281 DB01704] DB01281|Abatacept CD80;CD86 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways 26361:[DB01281 DB12874] DB01281|Abatacept CD80;CD86 DB12874|Quizartinib FLT3 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;FLT3 26362:[DB01281 DB05750] DB01281|Abatacept CD80;CD86 DB05750|AVE-1625 CNR1 common genes common pathways GO:0007165| signal transduction CD86;CNR1 26363:[DB01281 DB07127] DB01281|Abatacept CD80;CD86 DB07127|{4-[2,2-BIS(5-METHYL-1,2,4-OXADIAZOL-3-YL)-3-PHENYLPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways 26364:[DB01281 DB05394] DB01281|Abatacept CD80;CD86 DB05394|Corticorelin DBH common genes common pathways 26365:[DB01281 DB04115] DB01281|Abatacept CD80;CD86 DB04115|Berberine BIRC5 common genes common pathways GO:0008284| positive regulation of cell proliferation BIRC5;CD86 26366:[DB01281 DB02660] DB01281|Abatacept CD80;CD86 DB02660|Filaminast PDE4B common genes common pathways GO:0007165| signal transduction PDE4B;CD86 26367:[DB01281 DB13781] DB01281|Abatacept CD80;CD86 DB13781|Xamoterol ADRB1 common genes common pathways GO:0007165| signal transduction ADRB1;CD86 26368:[DB01281 DB00465] DB01281|Abatacept CD80;CD86 DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26369:[DB01281 DB00720] DB01281|Abatacept CD80;CD86 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation SLC25A5;CD86;PTGS2 GO:0016032| viral reproduction SLC25A5;CD86;SLC25A4;CD80;SLC25A6 26370:[DB01281 DB00653] DB01281|Abatacept CD80;CD86 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways 26371:[DB01281 DB01147] DB01281|Abatacept CD80;CD86 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 26372:[DB01281 DB02932] DB01281|Abatacept CD80;CD86 DB02932|(R)-Bicalutamide AR common genes common pathways GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 GO:0007165| signal transduction AR;CD86 26373:[DB01281 DB00573] DB01281|Abatacept CD80;CD86 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARA;PPARG;CD86 GO:0007165| signal transduction PPARG;CD86 26374:[DB01281 DB07677] DB01281|Abatacept CD80;CD86 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 26375:[DB01281 DB09329] DB01281|Abatacept CD80;CD86 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways 26376:[DB01281 DB07592] DB01281|Abatacept CD80;CD86 DB07592|(2R)-3-Methyl-1-phenyl-2-butanyl [(2S)-1-oxo-2-hexanyl]carbamate CTSK common genes common pathways 26377:[DB01281 DB04117] DB01281|Abatacept CD80;CD86 DB04117|4-(N,N-Dimethylamino)Cinnamoyl-Coa ECHS1 common genes common pathways 26378:[DB01281 DB02758] DB01281|Abatacept CD80;CD86 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways 26379:[DB01281 DB07509] DB01281|Abatacept CD80;CD86 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 GO:0007165| signal transduction PPARG;CD86 26380:[DB01281 DB01647] DB01281|Abatacept CD80;CD86 DB01647|Daxalipram PDE4B common genes common pathways GO:0007165| signal transduction CD86;PDE4B 26381:[DB01281 DB00869] DB01281|Abatacept CD80;CD86 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways 26382:[DB01281 DB02589] DB01281|Abatacept CD80;CD86 DB02589|Se-Ethyl-Isoselenourea NOS3 common genes common pathways 26383:[DB01281 DB04276] DB01281|Abatacept CD80;CD86 DB04276|N-[N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-Butyl]-Guanidine CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPN1;CD86 26384:[DB01281 DB03849] DB01281|Abatacept CD80;CD86 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways GO:0007165| signal transduction PDE4D;PDE4B;CD86 26385:[DB01281 DB07701] DB01281|Abatacept CD80;CD86 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways 26386:[DB01281 DB07561] DB01281|Abatacept CD80;CD86 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways 26387:[DB01281 DB00147] DB01281|Abatacept CD80;CD86 DB00147|Pyridoxal PDXK common genes common pathways 26388:[DB01281 DB01541] DB01281|Abatacept CD80;CD86 DB01541|Boldenone AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 26389:[DB01281 DB00133] DB01281|Abatacept CD80;CD86 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways 26390:[DB01281 DB07252] DB01281|Abatacept CD80;CD86 DB07252|3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide EPHB4 common genes common pathways 26391:[DB01281 DB05422] DB01281|Abatacept CD80;CD86 DB05422|OPC-14523 SLC6A4 common genes common pathways 26392:[DB01281 DB13749] DB01281|Abatacept CD80;CD86 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0007165| signal transduction ADCY1;CD86;GUCY1A2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;CD80 GO:0035556| intracellular signal transduction CD80;GUCY1A2;ADCY1 26393:[DB01281 DB12089] DB01281|Abatacept CD80;CD86 DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways 26394:[DB01281 DB07173] DB01281|Abatacept CD80;CD86 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 26395:[DB01281 DB08276] DB01281|Abatacept CD80;CD86 DB08276|trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-) MYH14 common genes common pathways 26396:[DB01281 DB02890] DB01281|Abatacept CD80;CD86 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways 26397:[DB01281 DB00066] DB01281|Abatacept CD80;CD86 DB00066|Follitropin FSHR common genes common pathways GO:0007165| signal transduction FSHR;CD86 26398:[DB01281 DB01873] DB01281|Abatacept CD80;CD86 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 26399:[DB01281 DB08809] DB01281|Abatacept CD80;CD86 DB08809|Dichloroacetic Acid PDK1;GSTZ1 common genes common pathways 26400:[DB01281 DB11595] DB01281|Abatacept CD80;CD86 DB11595|Atezolizumab CD274 common genes common pathways GO:0007165| signal transduction CD274;CD86 GO:0006955| immune response CD274;CD86 GO:0031295| T cell costimulation CD80;CD86;CD274 26401:[DB01281 DB01751] DB01281|Abatacept CD80;CD86 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways 26402:[DB01281 DB11135] DB01281|Abatacept CD80;CD86 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways GO:0007165| signal transduction TXNRD1;CD86 26403:[DB01281 DB00950] DB01281|Abatacept CD80;CD86 DB00950|Fexofenadine HRH1;ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3;SLC22A8 common genes common pathways GO:0007165| signal transduction CD86;HRH1 26404:[DB01281 DB02774] DB01281|Abatacept CD80;CD86 DB02774|1,3-Propandiol ARF1 common genes common pathways 26405:[DB01281 DB04856] DB01281|Abatacept CD80;CD86 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes common pathways GO:0007165| signal transduction CD86;CCKAR 26406:[DB01281 DB01582] DB01281|Abatacept CD80;CD86 DB01582|Sulfamethazine ALB common genes common pathways 26407:[DB01281 DB00397] DB01281|Abatacept CD80;CD86 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;CD86 GO:0007165| signal transduction ADRA2A;CD86;ADRB1;ADRA2C;ADRA2B;ADRB2;DRD1 26408:[DB01281 DB03944] DB01281|Abatacept CD80;CD86 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 26409:[DB01281 DB03413] DB01281|Abatacept CD80;CD86 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways 26410:[DB01281 DB04466] DB01281|Abatacept CD80;CD86 DB04466|SR12813 NR1I2 common genes common pathways GO:0007165| signal transduction NR1I2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;NR1I2 26411:[DB01281 DB07629] DB01281|Abatacept CD80;CD86 DB07629|N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 26412:[DB01281 DB02115] DB01281|Abatacept CD80;CD86 DB02115|Daidzin ALDH2;ABCG2 common genes common pathways 26413:[DB01281 DB09310] DB01281|Abatacept CD80;CD86 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 26414:[DB01281 DB03706] DB01281|Abatacept CD80;CD86 DB03706|1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane GSTM4 common genes common pathways 26415:[DB01281 DB08047] DB01281|Abatacept CD80;CD86 DB08047|4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 26416:[DB01281 DB05012] DB01281|Abatacept CD80;CD86 DB05012|XEN2174 SLC6A2 common genes common pathways 26417:[DB01281 DB07681] DB01281|Abatacept CD80;CD86 DB07681|DODECANESULFONATE ION BCHE common genes common pathways 26418:[DB01281 DB00728] DB01281|Abatacept CD80;CD86 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0007165| signal transduction HTR3A;CD86;CHRM2;CHRNA2 26419:[DB01281 DB02636] DB01281|Abatacept CD80;CD86 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways 26420:[DB01281 DB03026] DB01281|Abatacept CD80;CD86 DB03026|Phosphoglycolohydroxamic Acid TPI1;fucA common genes common pathways 26421:[DB01281 DB03017] DB01281|Abatacept CD80;CD86 DB03017|Lauric Acid ADH5;fabB;GM2A;fabH;HNF4A;PLA2G2A;VLDLR;GLTP;fabF;LTF;tonB;C8G;PLA2G2D;LY96;TLR4;PPARA;ALB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARA;HNF4A;CD86 GO:0002376| immune system process LY96;C8G;LTF;TLR4;CD86 GO:0006955| immune response CD86;TLR4 GO:0007165| signal transduction TLR4;CD86;VLDLR 26422:[DB01281 DB04436] DB01281|Abatacept CD80;CD86 DB04436|3-Fluorotyrosine SOD2 common genes common pathways 26423:[DB01281 DB03825] DB01281|Abatacept CD80;CD86 DB03825|Rhodamine 6G ABCC1 common genes common pathways 26424:[DB01281 DB13876] DB01281|Abatacept CD80;CD86 DB13876|Brofaromine MAOA common genes common pathways 26425:[DB01281 DB04374] DB01281|Abatacept CD80;CD86 DB04374|4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole HAO1 common genes common pathways 26426:[DB01281 DB09047] DB01281|Abatacept CD80;CD86 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways 26427:[DB01281 DB01666] DB01281|Abatacept CD80;CD86 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways GO:0007165| signal transduction CD86;FST 26428:[DB01281 DB04121] DB01281|Abatacept CD80;CD86 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways 26429:[DB01281 DB08631] DB01281|Abatacept CD80;CD86 DB08631|N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 26430:[DB01281 DB06249] DB01281|Abatacept CD80;CD86 DB06249|Arzoxifene ESR1;ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;ESR2;CD86 GO:0007165| signal transduction ESR2;CD86;ESR1 26431:[DB01281 DB08564] DB01281|Abatacept CD80;CD86 DB08564|(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process CD86;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD80;SRC;CD86 GO:0035556| intracellular signal transduction CD80;SRC GO:0007165| signal transduction CD86;SRC 26432:[DB01281 DB04941] DB01281|Abatacept CD80;CD86 DB04941|Crofelemer CFTR;ANO1 common genes common pathways 26433:[DB01281 DB06133] DB01281|Abatacept CD80;CD86 DB06133|Dimethylcurcumin AR common genes common pathways GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 GO:0007165| signal transduction CD86;AR 26434:[DB01281 DB07193] DB01281|Abatacept CD80;CD86 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;DPP4 GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 26435:[DB01281 DB07754] DB01281|Abatacept CD80;CD86 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways 26436:[DB01281 DB12379] DB01281|Abatacept CD80;CD86 DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;AHR;CD86 26437:[DB01281 DB01576] DB01281|Abatacept CD80;CD86 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0035556| intracellular signal transduction ADRA1A;CD80;ADRA1B GO:0007165| signal transduction ADRA1B;CD86;ADRA1A;TAAR1 26438:[DB01281 DB03615] DB01281|Abatacept CD80;CD86 DB03615|Ribostamycin P4HB;rpsL common genes common pathways 26439:[DB01281 DB13999] DB01281|Abatacept CD80;CD86 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 GO:0008284| positive regulation of cell proliferation F2;CD86;CALR 26440:[DB01281 DB07326] DB01281|Abatacept CD80;CD86 DB07326|6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide KDR common genes common pathways GO:0016032| viral reproduction KDR;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;KDR 26441:[DB01281 DB11598] DB01281|Abatacept CD80;CD86 DB11598|Antithrombin III human SERPINC1 common genes common pathways 26442:[DB01281 DB06205] DB01281|Abatacept CD80;CD86 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;TGFB1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;TGFB1;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;TGFB1 GO:0008284| positive regulation of cell proliferation TGFB1;CD86 26443:[DB01281 DB01838] DB01281|Abatacept CD80;CD86 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways 26444:[DB01281 DB08020] DB01281|Abatacept CD80;CD86 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways GO:0007165| signal transduction ESR2;CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR2;ESR1;CD80 26445:[DB01281 DB02236] DB01281|Abatacept CD80;CD86 DB02236|Glycinamide Ribonucleotide GART common genes common pathways 26446:[DB01281 DB01185] DB01281|Abatacept CD80;CD86 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0007165| signal transduction NR3C1;ESR1;AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;AR;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR 26447:[DB01281 DB00606] DB01281|Abatacept CD80;CD86 DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways 26448:[DB01281 DB08320] DB01281|Abatacept CD80;CD86 DB08320|DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 26449:[DB01281 DB01756] DB01281|Abatacept CD80;CD86 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 26450:[DB01281 DB08022] DB01281|Abatacept CD80;CD86 DB08022|(2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile PIM1 common genes common pathways 26451:[DB01281 DB07512] DB01281|Abatacept CD80;CD86 DB07512|7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE MAOB common genes common pathways 26452:[DB01281 DB06926] DB01281|Abatacept CD80;CD86 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 GO:0007165| signal transduction CD86;PPARG 26453:[DB01281 DB00999] DB01281|Abatacept CD80;CD86 DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways 26454:[DB01281 DB06691] DB01281|Abatacept CD80;CD86 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0007165| signal transduction CD86;HRH1 26455:[DB01281 DB07318] DB01281|Abatacept CD80;CD86 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways 26456:[DB01281 DB08170] DB01281|Abatacept CD80;CD86 DB08170|(1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE MMP7 common genes common pathways 26457:[DB01281 DB08180] DB01281|Abatacept CD80;CD86 DB08180|2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE FNTA;PGGT1B common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PGGT1B 26458:[DB01281 DB08087] DB01281|Abatacept CD80;CD86 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 26459:[DB01281 DB00146] DB01281|Abatacept CD80;CD86 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0007165| signal transduction CD86;VDR 26460:[DB01281 DB08872] DB01281|Abatacept CD80;CD86 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways 26461:[DB01281 DB03065] DB01281|Abatacept CD80;CD86 DB03065|7-Nitroindazole-2-Carboxamidine NOS3 common genes common pathways 26462:[DB01281 DB06421] DB01281|Abatacept CD80;CD86 DB06421|Declopramide TOP2A;TOP2B common genes common pathways 26463:[DB01281 DB13133] DB01281|Abatacept CD80;CD86 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;COL1A1 26464:[DB01281 DB07977] DB01281|Abatacept CD80;CD86 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways 26465:[DB01281 DB00233] DB01281|Abatacept CD80;CD86 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0006955| immune response CHUK;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CHUK;CD80;CD86 GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26466:[DB01281 DB03183] DB01281|Abatacept CD80;CD86 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction CD86;PDE4D 26467:[DB01281 DB11606] DB01281|Abatacept CD80;CD86 DB11606|Susoctocog alfa VWF common genes common pathways 26468:[DB01281 DB05155] DB01281|Abatacept CD80;CD86 DB05155|CR665 OPRK1 common genes common pathways GO:0006955| immune response CD86;OPRK1 GO:0007165| signal transduction CD86;OPRK1 26469:[DB01281 DB00585] DB01281|Abatacept CD80;CD86 DB00585|Nizatidine HRH2;BCHE;ABCB1 common genes common pathways GO:0006955| immune response CD86;HRH2 GO:0007165| signal transduction CD86;HRH2 26470:[DB01281 DB00561] DB01281|Abatacept CD80;CD86 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways 26471:[DB01281 DB02144] DB01281|Abatacept CD80;CD86 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways 26472:[DB01281 DB11455] DB01281|Abatacept CD80;CD86 DB11455|Robenacoxib PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26473:[DB01281 DB07227] DB01281|Abatacept CD80;CD86 DB07227|4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE FNTA;FNTB;PGGT1B common genes common pathways GO:0008284| positive regulation of cell proliferation PGGT1B;CD86 26474:[DB01281 DB12598] DB01281|Abatacept CD80;CD86 DB12598|Nafamostat F2;F10;F12;PRSS1;KLK1;ICAM1;SLC22A1;SLC22A2 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 GO:0046718| entry of virus into host cell ICAM1;CD86;CD80 GO:0016032| viral reproduction CD80;CD86;ICAM1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ICAM1 26475:[DB01281 DB02955] DB01281|Abatacept CD80;CD86 DB02955|Ricinoleic Acid CNR1;CNR2;TRPV1 common genes common pathways GO:0006955| immune response CD86;CNR2 GO:0007165| signal transduction CD86;CNR1;CNR2 26476:[DB01281 DB02553] DB01281|Abatacept CD80;CD86 DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways 26477:[DB01281 DB08529] DB01281|Abatacept CD80;CD86 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 26478:[DB01281 DB09266] DB01281|Abatacept CD80;CD86 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways GO:0007165| signal transduction CD86;MRC1 GO:0046718| entry of virus into host cell MRC1;CD86;CD80 GO:0016032| viral reproduction CD80;MRC1;CD86 26479:[DB01281 DB02011] DB01281|Abatacept CD80;CD86 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways 26480:[DB01281 DB04709] DB01281|Abatacept CD80;CD86 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 26481:[DB01281 DB01612] DB01281|Abatacept CD80;CD86 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0035556| intracellular signal transduction NPR1;CD80 26482:[DB01281 DB01777] DB01281|Abatacept CD80;CD86 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways 26483:[DB01281 DB09220] DB01281|Abatacept CD80;CD86 DB09220|Nicorandil ABCC9 common genes common pathways GO:0007165| signal transduction CD86;ABCC9 26484:[DB01281 DB14518] DB01281|Abatacept CD80;CD86 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP GO:0051897| positive regulation of protein kinase B signaling cascade CD86;APP;CD80 26485:[DB01281 DB07684] DB01281|Abatacept CD80;CD86 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways 26486:[DB01281 DB07300] DB01281|Abatacept CD80;CD86 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways GO:0031295| T cell costimulation PDPK1;CD86;CD80 GO:0035556| intracellular signal transduction CD80;PDPK1 26487:[DB01281 DB12733] DB01281|Abatacept CD80;CD86 DB12733|Dipraglurant GRM5 common genes common pathways GO:0007165| signal transduction CD86;GRM5 26488:[DB01281 DB02735] DB01281|Abatacept CD80;CD86 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways 26489:[DB01281 DB00867] DB01281|Abatacept CD80;CD86 DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0007165| signal transduction CD86;ADRB2 26490:[DB01281 DB02507] DB01281|Abatacept CD80;CD86 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways 26491:[DB01281 DB03280] DB01281|Abatacept CD80;CD86 DB03280|P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate DTYMK;tmk;tmk common genes common pathways 26492:[DB01281 DB06150] DB01281|Abatacept CD80;CD86 DB06150|Sulfadimethoxine CYP2C9 common genes common pathways 26493:[DB01281 DB03169] DB01281|Abatacept CD80;CD86 DB03169|(S)-Hmg-Coa HMGCR common genes common pathways GO:0008284| positive regulation of cell proliferation HMGCR;CD86 26494:[DB01281 DB01586] DB01281|Abatacept CD80;CD86 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction SLC10A1;CD86;CD80 GO:0046718| entry of virus into host cell SLC10A1;CD86;CD80 GO:0007165| signal transduction NR1H4;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;AKR1C2;CD86 GO:0008284| positive regulation of cell proliferation AKR1C2;CD86 GO:0002376| immune system process CD86;NR1H4 26495:[DB01281 DB00880] DB01281|Abatacept CD80;CD86 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways 26496:[DB01281 DB05495] DB01281|Abatacept CD80;CD86 DB05495|PG-530742 MMP9 common genes common pathways 26497:[DB01281 DB11113] DB01281|Abatacept CD80;CD86 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways GO:0007165| signal transduction PTGER3;PTGER4;CD86 GO:0006955| immune response PTGER4;CD86 26498:[DB01281 DB12339] DB01281|Abatacept CD80;CD86 DB12339|Radezolid RRBP1;NIP7 common genes common pathways 26499:[DB01281 DB11085] DB01281|Abatacept CD80;CD86 DB11085|Resorcinol TPO common genes common pathways 26500:[DB01281 DB00372] DB01281|Abatacept CD80;CD86 DB00372|Thiethylperazine DRD2;DRD1;DRD4 common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD4;DRD1;CD86;DRD2 26501:[DB01281 DB07932] DB01281|Abatacept CD80;CD86 DB07932|dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 26502:[DB01281 DB13772] DB01281|Abatacept CD80;CD86 DB13772|Rufloxacin CYP1A2 common genes common pathways 26503:[DB01281 DB03866] DB01281|Abatacept CD80;CD86 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26504:[DB01281 DB01926] DB01281|Abatacept CD80;CD86 DB01926|Carboxymycobactin S LCN2 common genes common pathways GO:0002376| immune system process LCN2;CD86 26505:[DB01281 DB02741] DB01281|Abatacept CD80;CD86 DB02741|CD564 RARG common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;RARG 26506:[DB01281 DB06077] DB01281|Abatacept CD80;CD86 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CD86 GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction HTR2A;CD86;DRD2 GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 26507:[DB01281 DB03085] DB01281|Abatacept CD80;CD86 DB03085|Glycolic acid G6PD;thiO common genes common pathways 26508:[DB01281 DB12579] DB01281|Abatacept CD80;CD86 DB12579|JNJ-37822681 DRD2 common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction CD86;DRD2 26509:[DB01281 DB03773] DB01281|Abatacept CD80;CD86 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways 26510:[DB01281 DB07460] DB01281|Abatacept CD80;CD86 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;PTK2;CD80 GO:0008284| positive regulation of cell proliferation PTK2;CD86 26511:[DB01281 DB04564] DB01281|Abatacept CD80;CD86 DB04564|Gluconolactone LCT common genes common pathways 26512:[DB01281 DB05116] DB01281|Abatacept CD80;CD86 DB05116|Thymectacin TYMS common genes common pathways 26513:[DB01281 DB00411] DB01281|Abatacept CD80;CD86 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0007165| signal transduction CHRNA2;CHRM1;CHRM2;CD86;CHRM4;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 26514:[DB01281 DB04860] DB01281|Abatacept CD80;CD86 DB04860|Isatoribine TLR7 common genes common pathways GO:0007165| signal transduction TLR7;CD86 GO:0006955| immune response TLR7;CD86 GO:0002376| immune system process CD86;TLR7 26515:[DB01281 DB00841] DB01281|Abatacept CD80;CD86 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 GO:0008284| positive regulation of cell proliferation ADRA1D;CD86 GO:0007165| signal transduction ADRA1D;CD86;ADRA1A;ADRB1;ADRB2;ESR1;ADRA1B GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A 26516:[DB01281 DB08228] DB01281|Abatacept CD80;CD86 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways 26517:[DB01281 DB05046] DB01281|Abatacept CD80;CD86 DB05046|V1003 OPRK1;OPRM1 common genes common pathways GO:0007165| signal transduction OPRM1;OPRK1;CD86 GO:0006955| immune response OPRK1;CD86 26518:[DB01281 DB06871] DB01281|Abatacept CD80;CD86 DB06871|17-METHYL-17-ALPHA-DIHYDROEQUILENIN ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 GO:0007165| signal transduction ESR1;CD86 26519:[DB01281 DB06901] DB01281|Abatacept CD80;CD86 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 26520:[DB01281 DB07691] DB01281|Abatacept CD80;CD86 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARD;CD80;CD86 GO:0008284| positive regulation of cell proliferation PPARD;CD86 26521:[DB01281 DB01214] DB01281|Abatacept CD80;CD86 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0007165| signal transduction CD86;ADRB1;ADRB2 26522:[DB01281 DB00044] DB01281|Abatacept CD80;CD86 DB00044|Lutropin alfa LHCGR common genes common pathways GO:0007165| signal transduction LHCGR;CD86 26523:[DB01281 DB09092] DB01281|Abatacept CD80;CD86 DB09092|Xanthinol RPL3;NNT;GAPDH;IDH3A;OGDH;MDH2 common genes common pathways 26524:[DB01281 DB07693] DB01281|Abatacept CD80;CD86 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways 26525:[DB01281 DB07253] DB01281|Abatacept CD80;CD86 DB07253|N'-(5-chloro-1,3-benzodioxol-4-yl)-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine EPHB4 common genes common pathways 26526:[DB01281 DB14059] DB01281|Abatacept CD80;CD86 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;RELA;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent CD86;NFKB1;CD80;RELA GO:0007165| signal transduction NFKB2;CD86;NFKB1 GO:0016032| viral reproduction CD80;RELA;CD86 26527:[DB01281 DB06064] DB01281|Abatacept CD80;CD86 DB06064|KAI-1455 PRKCE common genes common pathways GO:0035556| intracellular signal transduction PRKCE;CD80 GO:0007165| signal transduction CD86;PRKCE GO:0002376| immune system process CD86;PRKCE 26528:[DB01281 DB07517] DB01281|Abatacept CD80;CD86 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways 26529:[DB01281 DB08157] DB01281|Abatacept CD80;CD86 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways 26530:[DB01281 DB01309] DB01281|Abatacept CD80;CD86 DB01309|Insulin Glulisine INSR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade INSR;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent INSR;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;INSR GO:0035556| intracellular signal transduction CD80;INSR 26531:[DB01281 DB00040] DB01281|Abatacept CD80;CD86 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways GO:0008284| positive regulation of cell proliferation GLP2R;CD86 GO:0007165| signal transduction GLP1R;GLP2R;CD86;GCGR 26532:[DB01281 DB04016] DB01281|Abatacept CD80;CD86 DB04016|2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid CTSG;CMA1 common genes common pathways GO:0006955| immune response CTSG;CD86 26533:[DB01281 DB11087] DB01281|Abatacept CD80;CD86 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;NR1I2;CD80 GO:0007165| signal transduction NR1I2;CD86 26534:[DB01281 DB01700] DB01281|Abatacept CD80;CD86 DB01700|AICA ribonucleotide ATIC common genes common pathways 26535:[DB01281 DB05455] DB01281|Abatacept CD80;CD86 DB05455|SR 121463 AVPR1B common genes common pathways GO:0007165| signal transduction CD86;AVPR1B 26536:[DB01281 DB14034] DB01281|Abatacept CD80;CD86 DB14034|Darglitazone PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 26537:[DB01281 DB03100] DB01281|Abatacept CD80;CD86 DB03100|6-Nitroindazole NOS2;NOS3 common genes common pathways 26538:[DB01281 DB07559] DB01281|Abatacept CD80;CD86 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways 26539:[DB01281 DB00640] DB01281|Abatacept CD80;CD86 DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways GO:0007165| signal transduction ADORA3;ADORA2A;ADORA1;ADORA2B;CD86 26540:[DB01281 DB04429] DB01281|Abatacept CD80;CD86 DB04429|4'-Hydroxyflavanone SHBG common genes common pathways 26541:[DB01281 DB05018] DB01281|Abatacept CD80;CD86 DB05018|Migalastat GLA;UGT1A1 common genes common pathways 26542:[DB01281 DB08692] DB01281|Abatacept CD80;CD86 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 26543:[DB01281 DB04881] DB01281|Abatacept CD80;CD86 DB04881|Elacridar ABCB1;ABCG2;SLCO1B1 common genes common pathways 26544:[DB01281 DB03962] DB01281|Abatacept CD80;CD86 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways 26545:[DB01281 DB06153] DB01281|Abatacept CD80;CD86 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;HTR2B;CD86;CHRM1;HTR1A;HTR2A GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A GO:0046718| entry of virus into host cell HTR2A;CD80;CD86 GO:0007165| signal transduction HTR1B;ADRA1A;ADRA2A;HTR2B;HTR2C;CD86;ADRA1D;CHRM3;ADRA1B;HTR1D;HRH1;ADRA2C;CHRM1;HTR1A;CHRM2;HTR2A;ADRA2B 26546:[DB01281 DB08736] DB01281|Abatacept CD80;CD86 DB08736|S,R-Warfarin alcohol ALB common genes common pathways 26547:[DB01281 DB00695] DB01281|Abatacept CD80;CD86 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways 26548:[DB01281 DB09129] DB01281|Abatacept CD80;CD86 DB09129|Chromic chloride INSR common genes common pathways GO:0035556| intracellular signal transduction CD80;INSR GO:0008284| positive regulation of cell proliferation INSR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;INSR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;INSR 26549:[DB01281 DB06796] DB01281|Abatacept CD80;CD86 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways 26550:[DB01281 DB06533] DB01281|Abatacept CD80;CD86 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80;PPARA 26551:[DB01281 DB06472] DB01281|Abatacept CD80;CD86 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction CD80;CD86;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;CD80 GO:0046718| entry of virus into host cell CD80;ITGB3;CD86 26552:[DB01281 DB07247] DB01281|Abatacept CD80;CD86 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F3;F7;CD86 26553:[DB01281 DB07140] DB01281|Abatacept CD80;CD86 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 26554:[DB01281 DB05916] DB01281|Abatacept CD80;CD86 DB05916|CT-011 PDCD1 common genes common pathways GO:0007165| signal transduction CD86;PDCD1 GO:0031295| T cell costimulation CD86;PDCD1;CD80 GO:0002376| immune system process PDCD1;CD86 26555:[DB01281 DB07814] DB01281|Abatacept CD80;CD86 DB07814|Gibberellic acid AADACL2 common genes common pathways 26556:[DB01281 DB01902] DB01281|Abatacept CD80;CD86 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways 26557:[DB01281 DB00060] DB01281|Abatacept CD80;CD86 DB00060|Interferon beta-1a IFNAR1;IFNAR2 common genes common pathways 26558:[DB01281 DB04495] DB01281|Abatacept CD80;CD86 DB04495|RU81843 SRC common genes common pathways GO:0007165| signal transduction CD86;SRC GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction SRC;CD80;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0002376| immune system process CD86;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;SRC;CD86 26559:[DB01281 DB02271] DB01281|Abatacept CD80;CD86 DB02271|S-(2-Oxo)Pentadecylcoa NMT2 common genes common pathways 26560:[DB01281 DB02838] DB01281|Abatacept CD80;CD86 DB02838|3,4-Dihydro-2h-Pyrrolium-5-Carboxylate DAO common genes common pathways 26561:[DB01281 DB06750] DB01281|Abatacept CD80;CD86 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways 26562:[DB01281 DB00743] DB01281|Abatacept CD80;CD86 DB00743|Gadobenic acid ALB common genes common pathways 26563:[DB01281 DB03609] DB01281|Abatacept CD80;CD86 DB03609|3-Deoxyguanosine PNP common genes common pathways GO:0006955| immune response CD86;PNP 26564:[DB01281 DB13949] DB01281|Abatacept CD80;CD86 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways GO:0046718| entry of virus into host cell CD86;ITGB3;CD80;TFRC GO:0016032| viral reproduction TFRC;CD80;CD86;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ITGB3 GO:0008284| positive regulation of cell proliferation CD86;CALR 26565:[DB01281 DB08756] DB01281|Abatacept CD80;CD86 DB08756|(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE PRKACA;PKIA;ROCK1;ROCK2 common genes common pathways GO:0007165| signal transduction ROCK1;CD86 GO:0035556| intracellular signal transduction ROCK2;ROCK1;CD80 26566:[DB01281 DB04404] DB01281|Abatacept CD80;CD86 DB04404|Allosamizoline CHIT1 common genes common pathways GO:0006955| immune response CD86;CHIT1 26567:[DB01281 DB08811] DB01281|Abatacept CD80;CD86 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;PDE3A;PDE2A;PDE10A;PDE4A 26568:[DB01281 DB01092] DB01281|Abatacept CD80;CD86 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways 26569:[DB01281 DB01428] DB01281|Abatacept CD80;CD86 DB01428|Oxybenzone PGR;AR;ESR1;ESR2 common genes common pathways GO:0007165| signal transduction ESR2;CD86;PGR;ESR1;AR GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;AR;CD80;ESR1 26570:[DB01281 DB01077] DB01281|Abatacept CD80;CD86 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 26571:[DB01281 DB03255] DB01281|Abatacept CD80;CD86 DB03255|Phenol cobT;ALB common genes common pathways 26572:[DB01281 DB07437] DB01281|Abatacept CD80;CD86 DB07437|1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE UPP1 common genes common pathways 26573:[DB01281 DB05125] DB01281|Abatacept CD80;CD86 DB05125|SC12267 DHODH common genes common pathways 26574:[DB01281 DB04892] DB01281|Abatacept CD80;CD86 DB04892|Phenserine ACHE;BCHE;APP common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;APP;CD86 26575:[DB01281 DB05487] DB01281|Abatacept CD80;CD86 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NFKB1;ESR1;CD80;CD86 GO:0007165| signal transduction NFKB1;ESR1;CD86;NFKB2 26576:[DB01281 DB00942] DB01281|Abatacept CD80;CD86 DB00942|Cycrimine CHRM1 common genes common pathways GO:0007165| signal transduction CD86;CHRM1 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 26577:[DB01281 DB02761] DB01281|Abatacept CD80;CD86 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways 26578:[DB01281 DB08201] DB01281|Abatacept CD80;CD86 DB08201|(1S)-menthyl hexyl phosphonate group BCHE common genes common pathways 26579:[DB01281 DB08077] DB01281|Abatacept CD80;CD86 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways 26580:[DB01281 DB14533] DB01281|Abatacept CD80;CD86 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0046718| entry of virus into host cell SIVA1;CD80;CD86;IDE GO:0007165| signal transduction PDIA3;BDKRB1;FGA;CD86;IGFALS;C3;ESR1;JUP GO:0016032| viral reproduction SIVA1;CD80;CFH;TP73;CD86;MDM2;TP53;APOA2;HDAC1;IDE GO:0006955| immune response IGKV1-17;JCHAIN;CD86;C8B;C1R;IL3;IGHA1;C1QC;C3;IGLV3-21;VTN;C8A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL3;AGT;INS;CD80;VTN;TP53;APP GO:0002376| immune system process CFH;FCN3;FGA;IGKV1-17;CD86;CFB;CLU;C1R;C1QB;C8B;IGHM;C8G;C4B;PGLYRP2;C4BPA;S100A8;IGLV3-21;C4BPB;C8A;S100A9;C1S;C5;IGHA1;C3;CFI;C1QC GO:0045893| positive regulation of transcription, DNA-dependent AGT;MT3;CD80;ESR1;TP73;CD86;TP53;HDAC1;HDAC4 GO:0002250| adaptive immune response IGHA1;IGLV3-21;IGHM;JCHAIN;CD86;IGKV1-17;FGA GO:0051897| positive regulation of protein kinase B signaling cascade CD86;APP;INS;CD80 GO:0008284| positive regulation of cell proliferation IL3;AGT;INS;KRT6A;F2;CD86;MDM2;FN1;HDAC4;HDAC1 26581:[DB01281 DB06837] DB01281|Abatacept CD80;CD86 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways 26582:[DB01281 DB07962] DB01281|Abatacept CD80;CD86 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways 26583:[DB01281 DB03861] DB01281|Abatacept CD80;CD86 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways 26584:[DB01281 DB07714] DB01281|Abatacept CD80;CD86 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways 26585:[DB01281 DB01966] DB01281|Abatacept CD80;CD86 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways 26586:[DB01281 DB04816] DB01281|Abatacept CD80;CD86 DB04816|Dantron ALB common genes common pathways 26587:[DB01281 DB05076] DB01281|Abatacept CD80;CD86 DB05076|Fenretinide RBP4 common genes common pathways 26588:[DB01281 DB01893] DB01281|Abatacept CD80;CD86 DB01893|N6-Benzyl Adenosine-5'-Diphosphate SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0035556| intracellular signal transduction CD80;SRC GO:0016032| viral reproduction CD86;SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0007165| signal transduction SRC;CD86 26589:[DB01281 DB08660] DB01281|Abatacept CD80;CD86 DB08660|1,2,5,8-tetrahydroxyanthracene-9,10-dione CSNK2A1 common genes common pathways GO:0007165| signal transduction CSNK2A1;CD86 GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 26590:[DB01281 DB01698] DB01281|Abatacept CD80;CD86 DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AKR1C3 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;AKR1C3;CD80 26591:[DB01281 DB05713] DB01281|Abatacept CD80;CD86 DB05713|LY-517717 F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 26592:[DB01281 DB00992] DB01281|Abatacept CD80;CD86 DB00992|Methyl aminolevulinate FCGR1A common genes common pathways GO:0002376| immune system process CD86;FCGR1A GO:0006955| immune response FCGR1A;CD86 GO:0007165| signal transduction CD86;FCGR1A 26593:[DB01281 DB03994] DB01281|Abatacept CD80;CD86 DB03994|Ethanolamine ANXA3 common genes common pathways 26594:[DB01281 DB04400] DB01281|Abatacept CD80;CD86 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PCBD1;CD80;CD86 26595:[DB01281 DB01791] DB01281|Abatacept CD80;CD86 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways GO:0007165| signal transduction PDE4A;PDE4D;CD86;PDE4C;PDE4B 26596:[DB01281 DB00896] DB01281|Abatacept CD80;CD86 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction CD86;NR3C1 26597:[DB01281 DB04594] DB01281|Abatacept CD80;CD86 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways 26598:[DB01281 DB00967] DB01281|Abatacept CD80;CD86 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 26599:[DB01281 DB03645] DB01281|Abatacept CD80;CD86 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways 26600:[DB01281 DB11827] DB01281|Abatacept CD80;CD86 DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways 26601:[DB01281 DB02581] DB01281|Abatacept CD80;CD86 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways GO:0006955| immune response CD86;IL2 GO:0002250| adaptive immune response CD86;IL2 GO:0008284| positive regulation of cell proliferation IL2;CD86 GO:0002376| immune system process IL2;CD86 26602:[DB01281 DB00485] DB01281|Abatacept CD80;CD86 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways 26603:[DB01281 DB06599] DB01281|Abatacept CD80;CD86 DB06599|Lexatumumab TNFRSF10B common genes common pathways GO:0006955| immune response TNFRSF10B;CD86 GO:0007165| signal transduction TNFRSF10B;CD86 26604:[DB01281 DB05552] DB01281|Abatacept CD80;CD86 DB05552|TG100-115 PIK3CD;PIK3CG common genes common pathways GO:0007165| signal transduction CD86;PIK3CD GO:0051897| positive regulation of protein kinase B signaling cascade CD80;PIK3CD;PIK3CG;CD86 GO:0002250| adaptive immune response PIK3CD;PIK3CG;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;PIK3CD;PIK3CG;CD80 GO:0002376| immune system process PIK3CG;PIK3CD;CD86 26605:[DB01281 DB07148] DB01281|Abatacept CD80;CD86 DB07148|(6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one PREP common genes common pathways 26606:[DB01281 DB03132] DB01281|Abatacept CD80;CD86 DB03132|3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid TPI1 common genes common pathways 26607:[DB01281 DB05471] DB01281|Abatacept CD80;CD86 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;NFKB1 GO:0007165| signal transduction NFKB2;CD86;NFKB1 26608:[DB01281 DB06870] DB01281|Abatacept CD80;CD86 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;AR;CD80 GO:0008284| positive regulation of cell proliferation CD86;AR 26609:[DB01281 DB07395] DB01281|Abatacept CD80;CD86 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways 26610:[DB01281 DB08119] DB01281|Abatacept CD80;CD86 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 26611:[DB01281 DB07072] DB01281|Abatacept CD80;CD86 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD86;DPP4;CD80 26612:[DB01281 DB06705] DB01281|Abatacept CD80;CD86 DB06705|Gadofosveset trisodium ALB common genes common pathways 26613:[DB01281 DB08934] DB01281|Abatacept CD80;CD86 DB08934|Sofosbuvir CTSA;HINT1;CMPK1;NME1;ABCB1;ABCG2 common genes common pathways GO:0007165| signal transduction HINT1;CD86 26614:[DB01281 DB01640] DB01281|Abatacept CD80;CD86 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways GO:0007165| signal transduction CD86;PDE3B 26615:[DB01281 DB02762] DB01281|Abatacept CD80;CD86 DB02762|RU79072 SRC common genes common pathways GO:0007165| signal transduction CD86;SRC GO:0035556| intracellular signal transduction CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction SRC;CD80;CD86 GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0002376| immune system process CD86;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC 26616:[DB01281 DB02988] DB01281|Abatacept CD80;CD86 DB02988|Imino-Tryptophan DAO common genes common pathways 26617:[DB01281 DB05708] DB01281|Abatacept CD80;CD86 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 GO:0007165| signal transduction CD86;CHRNA7 26618:[DB01281 DB08843] DB01281|Abatacept CD80;CD86 DB08843|GS 0573 SLC22A6 common genes common pathways 26619:[DB01281 DB00383] DB01281|Abatacept CD80;CD86 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CHRM1;CHRM2;CD86;CHRM3 26620:[DB01281 DB07613] DB01281|Abatacept CD80;CD86 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways GO:0007165| signal transduction HPGDS;CD86 26621:[DB01281 DB07261] DB01281|Abatacept CD80;CD86 DB07261|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 26622:[DB01281 DB06849] DB01281|Abatacept CD80;CD86 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways 26623:[DB01281 DB00616] DB01281|Abatacept CD80;CD86 DB00616|Candoxatril MME;ACE common genes common pathways 26624:[DB01281 DB08960] DB01281|Abatacept CD80;CD86 DB08960|Hexamethonium CHRNA2 common genes common pathways GO:0007165| signal transduction CD86;CHRNA2 26625:[DB01281 DB06147] DB01281|Abatacept CD80;CD86 DB06147|Sulfathiazole CYP19A1 common genes common pathways 26626:[DB01281 DB06716] DB01281|Abatacept CD80;CD86 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0007165| signal transduction GABRB3;CD86 26627:[DB01281 DB01662] DB01281|Abatacept CD80;CD86 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways 26628:[DB01281 DB07350] DB01281|Abatacept CD80;CD86 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways 26629:[DB01281 DB07849] DB01281|Abatacept CD80;CD86 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways 26630:[DB01281 DB03297] DB01281|Abatacept CD80;CD86 DB03297|Benzylsulfinic Acid HPN;SOD2;CMA1 common genes common pathways 26631:[DB01281 DB01497] DB01281|Abatacept CD80;CD86 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways GO:0006955| immune response OPRK1;CD86;OPRD1 GO:0007165| signal transduction TRIM13;OPRK1;CD86;OPRM1;OPRD1;POMC;OPRL1 26632:[DB01281 DB07007] DB01281|Abatacept CD80;CD86 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways 26633:[DB01281 DB09536] DB01281|Abatacept CD80;CD86 DB09536|Titanium dioxide MARCO common genes common pathways GO:0002376| immune system process CD86;MARCO 26634:[DB01281 DB03531] DB01281|Abatacept CD80;CD86 DB03531|Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone DAO common genes common pathways 26635:[DB01281 DB05253] DB01281|Abatacept CD80;CD86 DB05253|Proellex PGR common genes common pathways GO:0007165| signal transduction CD86;PGR 26636:[DB01281 DB04418] DB01281|Abatacept CD80;CD86 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways GO:0002376| immune system process CD86;ADSSL1 26637:[DB01281 DB00523] DB01281|Abatacept CD80;CD86 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0045630| positive regulation of T-helper 2 cell differentiation CD86;RARA GO:0045893| positive regulation of transcription, DNA-dependent CD86;RXRA;RARA;CD80 GO:0008284| positive regulation of cell proliferation RARG;RARA;CD86;RARB GO:0007165| signal transduction RARA;CRABP2;CRABP1;RARB;CD86 GO:0016032| viral reproduction CD86;RXRA;CD80 26638:[DB01281 DB00259] DB01281|Abatacept CD80;CD86 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways 26639:[DB01281 DB00306] DB01281|Abatacept CD80;CD86 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRD;GABRP;GABRA5;CD86;GABRA6;GABRE;GABRQ;GABRB1;GABRB3;CHRNA7;GRIA2;CHRNA4 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 26640:[DB01281 DB00288] DB01281|Abatacept CD80;CD86 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0002376| immune system process CD86;ANXA1 GO:0002250| adaptive immune response CD86;ANXA1 GO:0007165| signal transduction NR3C1;CD86;ANXA1 GO:0045627| positive regulation of T-helper 1 cell differentiation CD80;ANXA1 26641:[DB01281 DB08674] DB01281|Abatacept CD80;CD86 DB08674|(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways 26642:[DB01281 DB00156] DB01281|Abatacept CD80;CD86 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways 26643:[DB01281 DB03095] DB01281|Abatacept CD80;CD86 DB03095|Tetramethylammonium Ion GALE common genes common pathways 26644:[DB01281 DB13503] DB01281|Abatacept CD80;CD86 DB13503|Tyrothricin ACHE common genes common pathways 26645:[DB01281 DB09279] DB01281|Abatacept CD80;CD86 DB09279|Fimasartan AGTR1 common genes common pathways GO:0007165| signal transduction AGTR1;CD86 26646:[DB01281 DB03124] DB01281|Abatacept CD80;CD86 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways GO:0035556| intracellular signal transduction CASP3;CD80 26647:[DB01281 DB08626] DB01281|Abatacept CD80;CD86 DB08626|Thiorphan MME common genes common pathways 26648:[DB01281 DB05115] DB01281|Abatacept CD80;CD86 DB05115|NN344 INSR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;INSR GO:0035556| intracellular signal transduction CD80;INSR 26649:[DB01281 DB08345] DB01281|Abatacept CD80;CD86 DB08345|4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0007165| signal transduction CSNK2A1;CD86 GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 26650:[DB01281 DB06042] DB01281|Abatacept CD80;CD86 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways 26651:[DB01281 DB14724] DB01281|Abatacept CD80;CD86 DB14724|Emapalumab IFNG common genes common pathways GO:0002250| adaptive immune response IFNG;CD86 GO:0008284| positive regulation of cell proliferation IFNG;CD86 GO:0006955| immune response IFNG;CD86 26652:[DB01281 DB01832] DB01281|Abatacept CD80;CD86 DB01832|4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid FAH common genes common pathways 26653:[DB01281 DB03425] DB01281|Abatacept CD80;CD86 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways 26654:[DB01281 DB08060] DB01281|Abatacept CD80;CD86 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways 26655:[DB01281 DB05264] DB01281|Abatacept CD80;CD86 DB05264|NPI 32101 CSF2RB common genes common pathways GO:0007165| signal transduction CD86;CSF2RB 26656:[DB01281 DB01742] DB01281|Abatacept CD80;CD86 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways GO:0016032| viral reproduction PPIA;CD86;CD80 26657:[DB01281 DB00750] DB01281|Abatacept CD80;CD86 DB00750|Prilocaine SCN5A common genes common pathways 26658:[DB01281 DB05849] DB01281|Abatacept CD80;CD86 DB05849|NCX 950 ADRB2 common genes common pathways GO:0007165| signal transduction CD86;ADRB2 26659:[DB01281 DB03470] DB01281|Abatacept CD80;CD86 DB03470|Trypanothione TPR common genes common pathways GO:0016032| viral reproduction CD80;TPR;CD86 26660:[DB01281 DB08510] DB01281|Abatacept CD80;CD86 DB08510|5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0002250| adaptive immune response CD86;IGHG2 GO:0002376| immune system process IGHG2;CD86 26661:[DB01281 DB04445] DB01281|Abatacept CD80;CD86 DB04445|Mercuric iodide SULT2A1 common genes common pathways 26662:[DB01281 DB04133] DB01281|Abatacept CD80;CD86 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 26663:[DB01281 DB04934] DB01281|Abatacept CD80;CD86 DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways 26664:[DB01281 DB00751] DB01281|Abatacept CD80;CD86 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0007165| signal transduction CD86;ADRA2A;HTR7;ADRA1A;HRH2;HTR2A;HRH1 GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0006955| immune response HRH2;CD86 GO:0016032| viral reproduction CD86;HTR2A;CD80 GO:0035556| intracellular signal transduction ADRA1A;CD80 GO:0008284| positive regulation of cell proliferation HTR2A;ADRA2A;CD86 26665:[DB01281 DB01537] DB01281|Abatacept CD80;CD86 DB01537|4-Bromo-2,5-dimethoxyphenethylamine HTR2C;HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HTR2A GO:0007165| signal transduction CD86;HTR2C;HTR2A GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction CD86;CD80;HTR2A 26666:[DB01281 DB03666] DB01281|Abatacept CD80;CD86 DB03666|3'-Azido-3'-Deoxythymidine-5'-Monophosphate DTYMK;tmk common genes common pathways 26667:[DB01281 DB00621] DB01281|Abatacept CD80;CD86 DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;AR;CD80 GO:0008284| positive regulation of cell proliferation CD86;AR GO:0007165| signal transduction CD86;AR 26668:[DB01281 DB08972] DB01281|Abatacept CD80;CD86 DB08972|Flumequine CYP1A2 common genes common pathways 26669:[DB01281 DB00765] DB01281|Abatacept CD80;CD86 DB00765|Metyrosine TH common genes common pathways 26670:[DB01281 DB05824] DB01281|Abatacept CD80;CD86 DB05824|CNS-5161 GRIN1 common genes common pathways 26671:[DB01281 DB01109] DB01281|Abatacept CD80;CD86 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0006955| immune response CD86;PF4 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HGF GO:0007165| signal transduction FGF2;FGF1;FGF4;CD86 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade F10;HPSE;HGF;FGFR4;CD86;FGF4;FGF1;FGFR1;FGF2;CD80;FGFR2;FGF19 GO:0008284| positive regulation of cell proliferation HGF;CD86;FGFR4;FGF4;FGF1;FGFR1;FGF2;FGFR2;FGF19 GO:0046854| phosphatidylinositol phosphorylation HGF;FGFR4;CD86;FGF4;FGF1;FGFR1;FGF2;CD80;FGFR2;FGF19 26672:[DB01281 DB03988] DB01281|Abatacept CD80;CD86 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways GO:0008284| positive regulation of cell proliferation ADCYAP1;CD86 26673:[DB01281 DB11793] DB01281|Abatacept CD80;CD86 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways 26674:[DB01281 DB03316] DB01281|Abatacept CD80;CD86 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways GO:0006955| immune response CD86;TNFSF13B GO:0007165| signal transduction CD86;TNFSF13B GO:0045893| positive regulation of transcription, DNA-dependent TGFB3;CD80;CD86 GO:0008284| positive regulation of cell proliferation TNFSF13B;CD86 GO:0031295| T cell costimulation CD80;CD86;TNFSF13B GO:0002376| immune system process CD86;TNFSF13B 26675:[DB01281 DB06185] DB01281|Abatacept CD80;CD86 DB06185|Forodesine PNP common genes common pathways GO:0006955| immune response CD86;PNP 26676:[DB01281 DB01445] DB01281|Abatacept CD80;CD86 DB01445|Bufotenine MAOA;MAOB common genes common pathways 26677:[DB01281 DB08445] DB01281|Abatacept CD80;CD86 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD80;DPP4;CD86 26678:[DB01281 DB05875] DB01281|Abatacept CD80;CD86 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26679:[DB01281 DB06989] DB01281|Abatacept CD80;CD86 DB06989|{4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways 26680:[DB01281 DB04880] DB01281|Abatacept CD80;CD86 DB04880|Enoximone PDE3A common genes common pathways GO:0007165| signal transduction PDE3A;CD86 26681:[DB01281 DB12007] DB01281|Abatacept CD80;CD86 DB12007|Isoflavone PPARA;PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;PPARA;CD80 26682:[DB01281 DB08801] DB01281|Abatacept CD80;CD86 DB08801|Dimetindene HRH1;CHRM2 common genes common pathways GO:0007165| signal transduction CHRM2;HRH1;CD86 26683:[DB01281 DB06932] DB01281|Abatacept CD80;CD86 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways GO:0035556| intracellular signal transduction CD80;PDPK1 GO:0031295| T cell costimulation PDPK1;CD86;CD80 26684:[DB01281 DB01762] DB01281|Abatacept CD80;CD86 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways 26685:[DB01281 DB02089] DB01281|Abatacept CD80;CD86 DB02089|CP-526423 PYGL common genes common pathways 26686:[DB01281 DB00527] DB01281|Abatacept CD80;CD86 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways 26687:[DB01281 DB00253] DB01281|Abatacept CD80;CD86 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 26688:[DB01281 DB05386] DB01281|Abatacept CD80;CD86 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways 26689:[DB01281 DB03430] DB01281|Abatacept CD80;CD86 DB03430|(2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile LCTL common genes common pathways 26690:[DB01281 DB07294] DB01281|Abatacept CD80;CD86 DB07294|3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid RARG common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;RARG 26691:[DB01281 DB05429] DB01281|Abatacept CD80;CD86 DB05429|CAT-213 CCL11 common genes common pathways GO:0007165| signal transduction CD86;CCL11 GO:0006955| immune response CD86;CCL11 26692:[DB01281 DB07689] DB01281|Abatacept CD80;CD86 DB07689|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways 26693:[DB01281 DB06127] DB01281|Abatacept CD80;CD86 DB06127|Bisegliptin DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0046718| entry of virus into host cell CD80;DPP4;CD86 26694:[DB01281 DB07574] DB01281|Abatacept CD80;CD86 DB07574|2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE STMN4;TUBB2B;TUBA1A;TUBA1C;TUBA1B common genes common pathways 26695:[DB01281 DB09051] DB01281|Abatacept CD80;CD86 DB09051|Elosulfase alfa GALNS common genes common pathways 26696:[DB01281 DB06781] DB01281|Abatacept CD80;CD86 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;NR3C1 26697:[DB01281 DB01615] DB01281|Abatacept CD80;CD86 DB01615|Aceprometazine HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 26698:[DB01281 DB00939] DB01281|Abatacept CD80;CD86 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26699:[DB01281 DB02800] DB01281|Abatacept CD80;CD86 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways 26700:[DB01281 DB04931] DB01281|Abatacept CD80;CD86 DB04931|Afamelanotide MC1R common genes common pathways GO:0035556| intracellular signal transduction CD80;MC1R GO:0007165| signal transduction CD86;MC1R GO:0051897| positive regulation of protein kinase B signaling cascade MC1R;CD86;CD80 26701:[DB01281 DB09151] DB01281|Abatacept CD80;CD86 DB09151|Flutemetamol (18F) APP common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade APP;CD86;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP 26702:[DB01281 DB05945] DB01281|Abatacept CD80;CD86 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways GO:0007165| signal transduction CD86;ANTXR1 26703:[DB01281 DB07815] DB01281|Abatacept CD80;CD86 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways 26704:[DB01281 DB03478] DB01281|Abatacept CD80;CD86 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways 26705:[DB01281 DB01481] DB01281|Abatacept CD80;CD86 DB01481|1-Testosterone AR common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR 26706:[DB01281 DB01892] DB01281|Abatacept CD80;CD86 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0007165| signal transduction CD86;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent CD80;NR1I2;CD86 26707:[DB01281 DB06823] DB01281|Abatacept CD80;CD86 DB06823|Tiopronin MPO common genes common pathways 26708:[DB01281 DB00369] DB01281|Abatacept CD80;CD86 DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways 26709:[DB01281 DB01141] DB01281|Abatacept CD80;CD86 DB01141|Micafungin COMT;ARSA common genes common pathways 26710:[DB01281 DB07183] DB01281|Abatacept CD80;CD86 DB07183|N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide KDR common genes common pathways GO:0016032| viral reproduction CD80;CD86;KDR GO:0008284| positive regulation of cell proliferation KDR;CD86 26711:[DB01281 DB06804] DB01281|Abatacept CD80;CD86 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26712:[DB01281 DB08678] DB01281|Abatacept CD80;CD86 DB08678|(4-ETHYLPHENYL)SULFAMIC ACID PTPRB common genes common pathways 26713:[DB01281 DB00826] DB01281|Abatacept CD80;CD86 DB00826|Natamycin CYP3A4 common genes common pathways 26714:[DB01281 DB04820] DB01281|Abatacept CD80;CD86 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways 26715:[DB01281 DB07182] DB01281|Abatacept CD80;CD86 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 26716:[DB01281 DB02008] DB01281|Abatacept CD80;CD86 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 26717:[DB01281 DB06754] DB01281|Abatacept CD80;CD86 DB06754|Danaparoid SERPINC1 common genes common pathways 26718:[DB01281 DB07537] DB01281|Abatacept CD80;CD86 DB07537|N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide KDR common genes common pathways GO:0016032| viral reproduction CD80;KDR;CD86 GO:0008284| positive regulation of cell proliferation CD86;KDR 26719:[DB01281 DB07486] DB01281|Abatacept CD80;CD86 DB07486|3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline ITGAL common genes common pathways GO:0007165| signal transduction ITGAL;CD86 26720:[DB01281 DB13346] DB01281|Abatacept CD80;CD86 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0009967| positive regulation of signal transduction CD80;HDAC6 GO:0008284| positive regulation of cell proliferation CD86;PTGS2 26721:[DB01281 DB08129] DB01281|Abatacept CD80;CD86 DB08129|(1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol PNMT common genes common pathways 26722:[DB01281 DB00099] DB01281|Abatacept CD80;CD86 DB00099|Filgrastim CSF3R;ELANE common genes common pathways GO:0007165| signal transduction CSF3R;CD86 26723:[DB01281 DB04326] DB01281|Abatacept CD80;CD86 DB04326|Dihydroxyacetone phosphate ALDOA;TPI1;ALDOB;fucA common genes common pathways 26724:[DB01281 DB03546] DB01281|Abatacept CD80;CD86 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 26725:[DB01281 DB00325] DB01281|Abatacept CD80;CD86 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0035556| intracellular signal transduction NPR1;CD80 26726:[DB01281 DB00287] DB01281|Abatacept CD80;CD86 DB00287|Travoprost PTGFR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGFR GO:0007165| signal transduction PTGFR;CD86 26727:[DB01281 DB01378] DB01281|Abatacept CD80;CD86 DB01378|Magnesium cation ATP1A1 common genes common pathways 26728:[DB01281 DB13931] DB01281|Abatacept CD80;CD86 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0007165| signal transduction CD86;ROCK1 GO:0035556| intracellular signal transduction CD80;ROCK1;ROCK2 26729:[DB01281 DB04837] DB01281|Abatacept CD80;CD86 DB04837|Clofedanol HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 26730:[DB01281 DB05161] DB01281|Abatacept CD80;CD86 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0008284| positive regulation of cell proliferation PRTN3;CD86 26731:[DB01281 DB07692] DB01281|Abatacept CD80;CD86 DB07692|1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine PKM common genes common pathways 26732:[DB01281 DB00179] DB01281|Abatacept CD80;CD86 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways 26733:[DB01281 DB08950] DB01281|Abatacept CD80;CD86 DB08950|Indoramin ADRA1A common genes common pathways GO:0035556| intracellular signal transduction ADRA1A;CD80 GO:0007165| signal transduction CD86;ADRA1A 26734:[DB01281 DB07879] DB01281|Abatacept CD80;CD86 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HDAC4 GO:0045893| positive regulation of transcription, DNA-dependent CD86;HDAC4;CD80 26735:[DB01281 DB07453] DB01281|Abatacept CD80;CD86 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways 26736:[DB01281 DB00257] DB01281|Abatacept CD80;CD86 DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0002376| immune system process KCNN4;CD86 GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CD86;CD80 GO:0007165| signal transduction NR1I2;CD86;NR1I3 GO:0006955| immune response CYP11B1;CD86 26737:[DB01281 DB02179] DB01281|Abatacept CD80;CD86 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways 26738:[DB01281 DB03747] DB01281|Abatacept CD80;CD86 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways 26739:[DB01281 DB06819] DB01281|Abatacept CD80;CD86 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways 26740:[DB01281 DB07668] DB01281|Abatacept CD80;CD86 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways 26741:[DB01281 DB07383] DB01281|Abatacept CD80;CD86 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways 26742:[DB01281 DB05304] DB01281|Abatacept CD80;CD86 DB05304|WX-G250 CA9;IL2 common genes common pathways GO:0002376| immune system process IL2;CD86 GO:0002250| adaptive immune response IL2;CD86 GO:0008284| positive regulation of cell proliferation IL2;CD86 GO:0006955| immune response IL2;CD86 26743:[DB01281 DB04885] DB01281|Abatacept CD80;CD86 DB04885|Cilansetron HTR3A common genes common pathways GO:0007165| signal transduction CD86;HTR3A 26744:[DB01281 DB00419] DB01281|Abatacept CD80;CD86 DB00419|Miglustat UGCG common genes common pathways 26745:[DB01281 DB14528] DB01281|Abatacept CD80;CD86 DB14528|Chromium gluconate CYB5A;TF common genes common pathways 26746:[DB01281 DB01763] DB01281|Abatacept CD80;CD86 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways 26747:[DB01281 DB00155] DB01281|Abatacept CD80;CD86 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0002376| immune system process CD86;PADI4 GO:0045893| positive regulation of transcription, DNA-dependent CD86;NOS1;CD80 26748:[DB01281 DB07096] DB01281|Abatacept CD80;CD86 DB07096|6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE PARP1 common genes common pathways 26749:[DB01281 DB08813] DB01281|Abatacept CD80;CD86 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;MYC GO:0045893| positive regulation of transcription, DNA-dependent CD86;MYC;FOS;CD80 26750:[DB01281 DB01091] DB01281|Abatacept CD80;CD86 DB01091|Butenafine SQLE common genes common pathways 26751:[DB01281 DB07003] DB01281|Abatacept CD80;CD86 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways 26752:[DB01281 DB00055] DB01281|Abatacept CD80;CD86 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;F2 GO:0006955| immune response CD86;PF4 GO:0007165| signal transduction THBD;CD86 26753:[DB01281 DB12340] DB01281|Abatacept CD80;CD86 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BCL2 26754:[DB01281 DB04606] DB01281|Abatacept CD80;CD86 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F7;CD86 26755:[DB01281 DB00524] DB01281|Abatacept CD80;CD86 DB00524|Metolazone SLC12A3 common genes common pathways 26756:[DB01281 DB04890] DB01281|Abatacept CD80;CD86 DB04890|Bepotastine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 26757:[DB01281 DB07992] DB01281|Abatacept CD80;CD86 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways 26758:[DB01281 DB03101] DB01281|Abatacept CD80;CD86 DB03101|Ribose-1-Phosphate PNP common genes common pathways GO:0006955| immune response PNP;CD86 26759:[DB01281 DB08055] DB01281|Abatacept CD80;CD86 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0046854| phosphatidylinositol phosphorylation LCK;CD86;CD80 GO:0031295| T cell costimulation LCK;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;LCK GO:0016032| viral reproduction CD80;LCK;CD86 26760:[DB01281 DB01776] DB01281|Abatacept CD80;CD86 DB01776|M-Cresol INS common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;INS;CD86 GO:0008284| positive regulation of cell proliferation CD86;INS GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;INS 26761:[DB01281 DB09087] DB01281|Abatacept CD80;CD86 DB09087|Potassium alum ALB common genes common pathways 26762:[DB01281 DB09121] DB01281|Abatacept CD80;CD86 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0035556| intracellular signal transduction CD80;ADCY5;ADCY2;ADCY1 GO:0007165| signal transduction CD86;ADCY1;ADCY2 26763:[DB01281 DB07342] DB01281|Abatacept CD80;CD86 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0035556| intracellular signal transduction CD80;HMOX1 26764:[DB01281 DB04377] DB01281|Abatacept CD80;CD86 DB04377|Meglutol HMGCR common genes common pathways GO:0008284| positive regulation of cell proliferation HMGCR;CD86 26765:[DB01281 DB08206] DB01281|Abatacept CD80;CD86 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways 26766:[DB01281 DB03010] DB01281|Abatacept CD80;CD86 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 26767:[DB01281 DB02147] DB01281|Abatacept CD80;CD86 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways GO:0006955| immune response C3;CD86 GO:0007165| signal transduction C3;CD86 GO:0002376| immune system process C3;CD86 26768:[DB01281 DB04106] DB01281|Abatacept CD80;CD86 DB04106|Fotemustine TXNRD1 common genes common pathways GO:0007165| signal transduction TXNRD1;CD86 26769:[DB01281 DB03042] DB01281|Abatacept CD80;CD86 DB03042|5-Phosphoarabinonic Acid GPI common genes common pathways 26770:[DB01281 DB00032] DB01281|Abatacept CD80;CD86 DB00032|Menotropins FSHR;LHCGR common genes common pathways GO:0007165| signal transduction FSHR;LHCGR;CD86 26771:[DB01281 DB03104] DB01281|Abatacept CD80;CD86 DB03104|RU82129 SRC common genes common pathways GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0007165| signal transduction CD86;SRC GO:0035556| intracellular signal transduction CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction SRC;CD80;CD86 26772:[DB01281 DB01672] DB01281|Abatacept CD80;CD86 DB01672|2,3-Dihydroxy-Benzoic Acid LCN2 common genes common pathways GO:0002376| immune system process CD86;LCN2 26773:[DB01281 DB00323] DB01281|Abatacept CD80;CD86 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways 26774:[DB01281 DB11652] DB01281|Abatacept CD80;CD86 DB11652|Tucatinib ERBB2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;ERBB2;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;ERBB2;CD86 GO:0007165| signal transduction ERBB2;CD86 26775:[DB01281 DB02141] DB01281|Abatacept CD80;CD86 DB02141|S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways 26776:[DB01281 DB08615] DB01281|Abatacept CD80;CD86 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways 26777:[DB01281 DB13158] DB01281|Abatacept CD80;CD86 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 26778:[DB01281 DB04112] DB01281|Abatacept CD80;CD86 DB04112|1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide PLA2G2A common genes common pathways 26779:[DB01281 DB02097] DB01281|Abatacept CD80;CD86 DB02097|Cytidine UCK2 common genes common pathways 26780:[DB01281 DB14042] DB01281|Abatacept CD80;CD86 DB14042|Galcanezumab CALCA;CALCB common genes common pathways GO:0007165| signal transduction CD86;CALCB 26781:[DB01281 DB05416] DB01281|Abatacept CD80;CD86 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARD;CD80;PPARA;CD86 GO:0008284| positive regulation of cell proliferation CD86;PPARD 26782:[DB01281 DB05993] DB01281|Abatacept CD80;CD86 DB05993|PRX-07034 HTR6 common genes common pathways GO:0007165| signal transduction HTR6;CD86 26783:[DB01281 DB13914] DB01281|Abatacept CD80;CD86 DB13914|Volixibat SLC10A2 common genes common pathways 26784:[DB01281 DB03317] DB01281|Abatacept CD80;CD86 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways 26785:[DB01281 DB04027] DB01281|Abatacept CD80;CD86 DB04027|D-Arginine CKM common genes common pathways 26786:[DB01281 DB06433] DB01281|Abatacept CD80;CD86 DB06433|Tezacitabine RRM1;TYMP common genes common pathways 26787:[DB01281 DB04516] DB01281|Abatacept CD80;CD86 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways 26788:[DB01281 DB00548] DB01281|Abatacept CD80;CD86 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways 26789:[DB01281 DB03109] DB01281|Abatacept CD80;CD86 DB03109|N-Acetyl-D-Allosamine CHIT1 common genes common pathways GO:0006955| immune response CD86;CHIT1 26790:[DB01281 DB00406] DB01281|Abatacept CD80;CD86 DB00406|Gentian violet cation SLC22A1 common genes common pathways 26791:[DB01281 DB09401] DB01281|Abatacept CD80;CD86 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BCL2L1;BCL2 26792:[DB01281 DB01818] DB01281|Abatacept CD80;CD86 DB01818|O3-Sulfonylgalactose MBL2 common genes common pathways GO:0002376| immune system process CD86;MBL2 26793:[DB01281 DB05309] DB01281|Abatacept CD80;CD86 DB05309|TP-508 FGF4 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation CD80;FGF4;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;FGF4 GO:0008284| positive regulation of cell proliferation FGF4;CD86 GO:0007165| signal transduction CD86;FGF4 26794:[DB01281 DB03621] DB01281|Abatacept CD80;CD86 DB03621|L-709,587 FKBP1A common genes common pathways 26795:[DB01281 DB05050] DB01281|Abatacept CD80;CD86 DB05050|ADL5859 OPRD1 common genes common pathways GO:0006955| immune response OPRD1;CD86 GO:0007165| signal transduction CD86;OPRD1 26796:[DB01281 DB07348] DB01281|Abatacept CD80;CD86 DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways 26797:[DB01281 DB00929] DB01281|Abatacept CD80;CD86 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways GO:0007165| signal transduction PTGER3;PTGER2;PTGER4;CD86 GO:0006955| immune response PTGER4;CD86 26798:[DB01281 DB01270] DB01281|Abatacept CD80;CD86 DB01270|Ranibizumab VEGFA common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;VEGFA GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA 26799:[DB01281 DB01581] DB01281|Abatacept CD80;CD86 DB01581|Sulfamerazine ALB common genes common pathways 26800:[DB01281 DB07246] DB01281|Abatacept CD80;CD86 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 26801:[DB01281 DB08810] DB01281|Abatacept CD80;CD86 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0007165| signal transduction CD86;HTR2A;HTR1A;HTR4 GO:0046718| entry of virus into host cell HTR2A;CD80;CD86 GO:0008284| positive regulation of cell proliferation CD86;HTR1A;HTR2A 26802:[DB01281 DB01000] DB01281|Abatacept CD80;CD86 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 26803:[DB01281 DB06154] DB01281|Abatacept CD80;CD86 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0035556| intracellular signal transduction CD80;GUCY1A2 GO:0007165| signal transduction GUCY1A2;CD86 26804:[DB01281 DB00847] DB01281|Abatacept CD80;CD86 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0007165| signal transduction CD86;NPY2R 26805:[DB01281 DB07029] DB01281|Abatacept CD80;CD86 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways 26806:[DB01281 DB06939] DB01281|Abatacept CD80;CD86 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD80;DPP4;CD86 26807:[DB01281 DB06162] DB01281|Abatacept CD80;CD86 DB06162|Lumiliximab FCER2 common genes common pathways 26808:[DB01281 DB04270] DB01281|Abatacept CD80;CD86 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARG;CD86 GO:0007165| signal transduction PPARG;CD86 26809:[DB01281 DB08186] DB01281|Abatacept CD80;CD86 DB08186|(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE KAT2B common genes common pathways GO:0016032| viral reproduction KAT2B;CD80;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;KAT2B 26810:[DB01281 DB06097] DB01281|Abatacept CD80;CD86 DB06097|GSK-923295 CENPE common genes common pathways 26811:[DB01281 DB09459] DB01281|Abatacept CD80;CD86 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways 26812:[DB01281 DB08200] DB01281|Abatacept CD80;CD86 DB08200|(1R)-menthyl hexyl phosphonate group BCHE common genes common pathways 26813:[DB01281 DB08916] DB01281|Abatacept CD80;CD86 DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation ERBB4;CD80;ERBB2;CD86;EGFR GO:0008284| positive regulation of cell proliferation ERBB4;CD86;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade ERBB4;CD80;ERBB2;CD86;EGFR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CD86;CD80;ERBB4 GO:0007165| signal transduction ERBB4;ERBB2;EGFR;CD86 GO:0046718| entry of virus into host cell CD80;CD86;EGFR GO:0035556| intracellular signal transduction CD80;EGFR 26814:[DB01281 DB05787] DB01281|Abatacept CD80;CD86 DB05787|LM-609 ITGB3 common genes common pathways GO:0016032| viral reproduction CD80;CD86;ITGB3 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ITGB3 GO:0046718| entry of virus into host cell ITGB3;CD86;CD80 26815:[DB01281 DB08884] DB01281|Abatacept CD80;CD86 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways 26816:[DB01281 DB12712] DB01281|Abatacept CD80;CD86 DB12712|Pilsicainide ABCB11 common genes common pathways 26817:[DB01281 DB12961] DB01281|Abatacept CD80;CD86 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways GO:0006955| immune response LTB4R;CD86 GO:0007165| signal transduction LTB4R;CD86;LTB4R2 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;PPARA 26818:[DB01281 DB05458] DB01281|Abatacept CD80;CD86 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways GO:0007165| signal transduction CD86;CHRNB2;CHRNA4 26819:[DB01281 DB05190] DB01281|Abatacept CD80;CD86 DB05190|XL281 BRAF;RAF1 common genes common pathways GO:0007165| signal transduction RAF1;BRAF;CD86 GO:0035556| intracellular signal transduction BRAF;RAF1;CD80 26820:[DB01281 DB08609] DB01281|Abatacept CD80;CD86 DB08609|(2R)-N-{4-[Ethyl(phenyl)sulfamoyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide PDK2 common genes common pathways 26821:[DB01281 DB01437] DB01281|Abatacept CD80;CD86 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0007165| signal transduction GABRB1;GABRQ;GABRE;GABRA6;GABRB3;GABRA5;GABRP;GABRD;CD86 26822:[DB01281 DB06778] DB01281|Abatacept CD80;CD86 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes common pathways 26823:[DB01281 DB01038] DB01281|Abatacept CD80;CD86 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways GO:0007165| signal transduction DRD5;DRD1;DRD2;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 26824:[DB01281 DB09028] DB01281|Abatacept CD80;CD86 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;CD86 GO:0007165| signal transduction CHRNB2;CD86;CHRNA3;CHRNA6;CHRNA7;CHRNA4 26825:[DB01281 DB08234] DB01281|Abatacept CD80;CD86 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways 26826:[DB01281 DB05777] DB01281|Abatacept CD80;CD86 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;CD86 26827:[DB01281 DB00452] DB01281|Abatacept CD80;CD86 DB00452|Framycetin rpsL;CXCR4 common genes common pathways GO:0007165| signal transduction CXCR4;CD86 GO:0016032| viral reproduction CD80;CXCR4;CD86 26828:[DB01281 DB04638] DB01281|Abatacept CD80;CD86 DB04638|2,5-DI-(TERT-BUTYL)-1,4,BENZOHYDROQUINONE ATP2A1 common genes common pathways 26829:[DB01281 DB03351] DB01281|Abatacept CD80;CD86 DB03351|Sri-9439 DHFR common genes common pathways 26830:[DB01281 DB00937] DB01281|Abatacept CD80;CD86 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways 26831:[DB01281 DB01199] DB01281|Abatacept CD80;CD86 DB01199|Tubocurarine CHRNA2;HTR3A;ACHE;CHRNA7;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0007165| signal transduction CD86;HTR3A;CHRNA7;CHRNA2 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 26832:[DB01281 DB13191] DB01281|Abatacept CD80;CD86 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways 26833:[DB01281 DB09067] DB01281|Abatacept CD80;CD86 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways GO:0007165| signal transduction CD86;CRHR1 GO:0006955| immune response CD86;CRHR1 26834:[DB01281 DB08605] DB01281|Abatacept CD80;CD86 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways 26835:[DB01281 DB05934] DB01281|Abatacept CD80;CD86 DB05934|CTCE-0214 CXCL12 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CXCL12 GO:0006955| immune response CXCL12;CD86 GO:0007165| signal transduction CXCL12;CD86 26836:[DB01281 DB06186] DB01281|Abatacept CD80;CD86 DB06186|Ipilimumab CTLA4 common genes common pathways GO:0002376| immune system process CTLA4;CD86 GO:0031295| T cell costimulation CD86;CTLA4;CD80 GO:0002250| adaptive immune response CD86;CTLA4 GO:0006955| immune response CD86;CTLA4 26837:[DB01281 DB06408] DB01281|Abatacept CD80;CD86 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0006955| immune response ENPP1;CD86 26838:[DB01281 DB03126] DB01281|Abatacept CD80;CD86 DB03126|Mant-Adp MYH14 common genes common pathways 26839:[DB01281 DB04977] DB01281|Abatacept CD80;CD86 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways 26840:[DB01281 DB01239] DB01281|Abatacept CD80;CD86 DB01239|Chlorprothixene DRD2;DRD1;DRD3;HTR2A;HTR2B;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2B;CD86;DRD3;CHRM1;HTR2A GO:0007165| signal transduction CHRM5;HRH1;CHRM1;HTR2A;CHRM2;DRD1;CHRM3;DRD3;DRD2;CHRM4;HTR2C;HTR2B;CD86 GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 26841:[DB01281 DB05931] DB01281|Abatacept CD80;CD86 DB05931|Pegdinetanib KDR common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;CD86 GO:0016032| viral reproduction CD80;KDR;CD86 26842:[DB01281 DB01520] DB01281|Abatacept CD80;CD86 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways GO:0007165| signal transduction CHRNA7;CD86 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 26843:[DB01281 DB00724] DB01281|Abatacept CD80;CD86 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways GO:0002376| immune system process TLR7;CD86;TLR8 GO:0007165| signal transduction CD86;TLR8;TLR7 GO:0006955| immune response CD86;TLR7 26844:[DB01281 DB06271] DB01281|Abatacept CD80;CD86 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 26845:[DB01281 DB03467] DB01281|Abatacept CD80;CD86 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0007165| signal transduction CD86;ESR2;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86;ESR2 26846:[DB01281 DB02230] DB01281|Abatacept CD80;CD86 DB02230|Immucillin-G PNP common genes common pathways GO:0006955| immune response PNP;CD86 26847:[DB01281 DB00364] DB01281|Abatacept CD80;CD86 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways GO:0007165| signal transduction FGB;FGF2;EGF;FGA;CD86;FGG GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation EGF;CD80 GO:0002376| immune system process CD86;FGA;FGB GO:0046854| phosphatidylinositol phosphorylation CD86;EGF;CD80;FGF2 GO:0008284| positive regulation of cell proliferation FGF2;EGF;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;FGF2;CD80;EGF GO:0002250| adaptive immune response FGB;FGA;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;FGF2;EGF 26848:[DB01281 DB02911] DB01281|Abatacept CD80;CD86 DB02911|2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine NOS3 common genes common pathways 26849:[DB01281 DB07579] DB01281|Abatacept CD80;CD86 DB07579|BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE APCS common genes common pathways 26850:[DB01281 DB07756] DB01281|Abatacept CD80;CD86 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways 26851:[DB01281 DB08612] DB01281|Abatacept CD80;CD86 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 26852:[DB01281 DB08347] DB01281|Abatacept CD80;CD86 DB08347|4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile ADRB1 common genes common pathways GO:0007165| signal transduction ADRB1;CD86 26853:[DB01281 DB07142] DB01281|Abatacept CD80;CD86 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways 26854:[DB01281 DB08360] DB01281|Abatacept CD80;CD86 DB08360|2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 GO:0007165| signal transduction CD86;CSNK2A1 26855:[DB01281 DB00875] DB01281|Abatacept CD80;CD86 DB00875|Flupentixol DRD2;HTR2A;DRD1;ADRA1A;CHRM1;DDC;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CHRM1;CD86 GO:0007165| signal transduction DRD1;HTR2A;CHRM1;CD86;DRD2;ADRA1A GO:0046718| entry of virus into host cell CD86;CD80;HTR2A GO:0035556| intracellular signal transduction CD80;DRD2;ADRA1A GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 26856:[DB01281 DB02888] DB01281|Abatacept CD80;CD86 DB02888|FKB-001 FKBP1A common genes common pathways 26857:[DB01281 DB03766] DB01281|Abatacept CD80;CD86 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways 26858:[DB01281 DB03552] DB01281|Abatacept CD80;CD86 DB03552|3-Tyrosine TH common genes common pathways 26859:[DB01281 DB02464] DB01281|Abatacept CD80;CD86 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways 26860:[DB01281 DB03585] DB01281|Abatacept CD80;CD86 DB03585|Oxyphenbutazone PLA2G2E;ALB;SLC22A6 common genes common pathways 26861:[DB01281 DB08208] DB01281|Abatacept CD80;CD86 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways GO:0007165| signal transduction CD86;MAP2K1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;MAP2K1 26862:[DB01281 DB02468] DB01281|Abatacept CD80;CD86 DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0035556| intracellular signal transduction CD80;HMOX1 26863:[DB01281 DB08000] DB01281|Abatacept CD80;CD86 DB08000|2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE AKR1B1 common genes common pathways 26864:[DB01281 DB00171] DB01281|Abatacept CD80;CD86 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0035556| intracellular signal transduction AKT1;CD80;ARAF;ADCY1 GO:0016032| viral reproduction CD80;SLC25A4;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;TNK2;CD80 GO:0007165| signal transduction CSNK2A1;AMHR2;P2RY11;ALK;AKT1;TNK2;ACVR1B;ABL2;ABCC8;ACVRL1;CSNK2B;ADCY1;PRKAA1;ARAF;CD86;NAE1;ABCC9 GO:0008284| positive regulation of cell proliferation CSNK2A1;AKT1;CD86;PRKAA1 GO:0045893| positive regulation of transcription, DNA-dependent ACVRL1;CD80;ACVR1;AKT1;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;PIK3CA;CD80 GO:0002250| adaptive immune response CD86;PIK3CA GO:0031295| T cell costimulation PIK3CA;CD80;AKT1;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;PIK3CA;CD86 26865:[DB01281 DB05766] DB01281|Abatacept CD80;CD86 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0008284| positive regulation of cell proliferation DRD3;CD86;CHRM1 GO:0007165| signal transduction DRD2;CD86;DRD3;CHRM1 GO:0035556| intracellular signal transduction CD80;DRD2 26866:[DB01281 DB00123] DB01281|Abatacept CD80;CD86 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways GO:0016032| viral reproduction CD86;KARS;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;KARS;CD80 26867:[DB01281 DB01812] DB01281|Abatacept CD80;CD86 DB01812|Adenosine-3'-5'-Diphosphate HS3ST1;SULT2B1;RNASE2;SULT1A1;HS3ST3A1;RNASE1;SULT2A1;SULT1E1;NDST1;acpS;SULT1B1;topA common genes common pathways 26868:[DB01281 DB08519] DB01281|Abatacept CD80;CD86 DB08519|N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0016032| viral reproduction KDR;CD86;CD80 GO:0008284| positive regulation of cell proliferation KDR;CD86 26869:[DB01281 DB09066] DB01281|Abatacept CD80;CD86 DB09066|Corifollitropin alfa FSHR common genes common pathways GO:0007165| signal transduction CD86;FSHR 26870:[DB01281 DB03909] DB01281|Abatacept CD80;CD86 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways GO:0035556| intracellular signal transduction CD80;INSR GO:0008284| positive regulation of cell proliferation INSR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;INSR GO:0045893| positive regulation of transcription, DNA-dependent CD86;INSR;CD80 26871:[DB01281 DB02152] DB01281|Abatacept CD80;CD86 DB02152|K-252a MET;MAP2K1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;MET;CD86 GO:0045893| positive regulation of transcription, DNA-dependent MAP2K1;CD80;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;CD80;MET GO:0007165| signal transduction MET;MAP2K1;CD86 26872:[DB01281 DB03277] DB01281|Abatacept CD80;CD86 DB03277|alpha-maltotriose AMY2B common genes common pathways 26873:[DB01281 DB04875] DB01281|Abatacept CD80;CD86 DB04875|Pralnacasan CASP1 common genes common pathways GO:0007165| signal transduction CASP1;CD86 26874:[DB01281 DB09215] DB01281|Abatacept CD80;CD86 DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26875:[DB01281 DB08205] DB01281|Abatacept CD80;CD86 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways 26876:[DB01281 DB05223] DB01281|Abatacept CD80;CD86 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0008284| positive regulation of cell proliferation HDAC2;CD86;HDAC1 GO:0045893| positive regulation of transcription, DNA-dependent HDAC2;CD80;CD86;HDAC1 GO:0009967| positive regulation of signal transduction CD80;HDAC6 GO:0016032| viral reproduction CD80;HDAC1;CD86 26877:[DB01281 DB03788] DB01281|Abatacept CD80;CD86 DB03788|GC-24 THRB common genes common pathways 26878:[DB01281 DB11148] DB01281|Abatacept CD80;CD86 DB11148|Butamben CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;BCHE;ORM1;ALB common genes common pathways GO:0007165| signal transduction CACNA1I;CD86 26879:[DB01281 DB02678] DB01281|Abatacept CD80;CD86 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways 26880:[DB01281 DB12698] DB01281|Abatacept CD80;CD86 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD4;CD80 GO:0016032| viral reproduction CCR5;CXCR4;CD86;CD4;CD80 GO:0006955| immune response CD86;CCR5;CD4 GO:0007165| signal transduction CD4;CCR5;CXCR4;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD4;CD86 GO:0002250| adaptive immune response CD86;CD4 GO:0031295| T cell costimulation CD80;CD4;CD86 GO:0002376| immune system process CD86;CD4 GO:0045086| positive regulation of interleukin-2 biosynthetic process CD80;CD4;CD86 26881:[DB01281 DB01597] DB01281|Abatacept CD80;CD86 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways 26882:[DB01281 DB04048] DB01281|Abatacept CD80;CD86 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways 26883:[DB01281 DB01709] DB01281|Abatacept CD80;CD86 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways 26884:[DB01281 DB00031] DB01281|Abatacept CD80;CD86 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0016032| viral reproduction CD80;KRT8;CD86 GO:0007165| signal transduction FGA;PLAUR;CD86 GO:0002250| adaptive immune response FGA;CD86 GO:0008284| positive regulation of cell proliferation CD86;CALR GO:0002376| immune system process CD86;FGA 26885:[DB01281 DB09526] DB01281|Abatacept CD80;CD86 DB09526|Hydroquinone TYR;ALB common genes common pathways 26886:[DB01281 DB07456] DB01281|Abatacept CD80;CD86 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways GO:0031295| T cell costimulation CD80;CD86;PDPK1 GO:0035556| intracellular signal transduction CD80;PDPK1 26887:[DB01281 DB08467] DB01281|Abatacept CD80;CD86 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways GO:0007165| signal transduction CRABP2;CD86 26888:[DB01281 DB09027] DB01281|Abatacept CD80;CD86 DB09027|Ledipasvir ABCB1;ABCG2 common genes common pathways 26889:[DB01281 DB04389] DB01281|Abatacept CD80;CD86 DB04389|Ado-P-Ch2-P-Ps-Ado FHIT common genes common pathways 26890:[DB01281 DB08654] DB01281|Abatacept CD80;CD86 DB08654|TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 26891:[DB01281 DB01207] DB01281|Abatacept CD80;CD86 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0007165| signal transduction TBXA2R;CD86 26892:[DB01281 DB00043] DB01281|Abatacept CD80;CD86 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways GO:0007165| signal transduction MS4A2;CD86 GO:0006955| immune response MS4A2;CD86 26893:[DB01281 DB01194] DB01281|Abatacept CD80;CD86 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways 26894:[DB01281 DB09343] DB01281|Abatacept CD80;CD86 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways 26895:[DB01281 DB08608] DB01281|Abatacept CD80;CD86 DB08608|4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE PDK2 common genes common pathways 26896:[DB01281 DB00974] DB01281|Abatacept CD80;CD86 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways 26897:[DB01281 DB00240] DB01281|Abatacept CD80;CD86 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 26898:[DB01281 DB05282] DB01281|Abatacept CD80;CD86 DB05282|MCC AIFM1 common genes common pathways 26899:[DB01281 DB00954] DB01281|Abatacept CD80;CD86 DB00954|Dirithromycin CYP3A4 common genes common pathways 26900:[DB01281 DB05249] DB01281|Abatacept CD80;CD86 DB05249|FavId CSF3R common genes common pathways GO:0007165| signal transduction CSF3R;CD86 26901:[DB01281 DB08448] DB01281|Abatacept CD80;CD86 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways 26902:[DB01281 DB03690] DB01281|Abatacept CD80;CD86 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways 26903:[DB01281 DB02850] DB01281|Abatacept CD80;CD86 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways 26904:[DB01281 DB03608] DB01281|Abatacept CD80;CD86 DB03608|Diminazene PRDX5;PRSS1;AOC1 common genes common pathways 26905:[DB01281 DB06600] DB01281|Abatacept CD80;CD86 DB06600|Nemonoxacin CYP1A2 common genes common pathways 26906:[DB01281 DB06497] DB01281|Abatacept CD80;CD86 DB06497|Aplaviroc CCR5 common genes common pathways GO:0007165| signal transduction CCR5;CD86 GO:0006955| immune response CD86;CCR5 GO:0016032| viral reproduction CD80;CD86;CCR5 26907:[DB01281 DB08707] DB01281|Abatacept CD80;CD86 DB08707|4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine PIM1 common genes common pathways 26908:[DB01281 DB07717] DB01281|Abatacept CD80;CD86 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 26909:[DB01281 DB00846] DB01281|Abatacept CD80;CD86 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction CD86;NR3C1 26910:[DB01281 DB04585] DB01281|Abatacept CD80;CD86 DB04585|DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID ARG1 common genes common pathways GO:0002250| adaptive immune response ARG1;CD86 GO:0002376| immune system process ARG1;CD86 26911:[DB01281 DB01125] DB01281|Abatacept CD80;CD86 DB01125|Anisindione GGCX common genes common pathways 26912:[DB01281 DB02205] DB01281|Abatacept CD80;CD86 DB02205|6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One GAPDHS common genes common pathways 26913:[DB01281 DB01606] DB01281|Abatacept CD80;CD86 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways 26914:[DB01281 DB00360] DB01281|Abatacept CD80;CD86 DB00360|Sapropterin PAH;NOS3;TH;TPH1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26915:[DB01281 DB03191] DB01281|Abatacept CD80;CD86 DB03191|3-Oxiran-2ylalanine MAT1A common genes common pathways 26916:[DB01281 DB06909] DB01281|Abatacept CD80;CD86 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways GO:0007165| signal transduction CD86;PDE4B 26917:[DB01281 DB00481] DB01281|Abatacept CD80;CD86 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86;ESR2 GO:0006955| immune response SERPINB9;CD86 GO:0007165| signal transduction ESR1;ESR2;CD86 26918:[DB01281 DB12095] DB01281|Abatacept CD80;CD86 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways 26919:[DB01281 DB03233] DB01281|Abatacept CD80;CD86 DB03233|Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways 26920:[DB01281 DB08806] DB01281|Abatacept CD80;CD86 DB08806|Roxatidine acetate HRH2 common genes common pathways GO:0006955| immune response HRH2;CD86 GO:0007165| signal transduction HRH2;CD86 26921:[DB01281 DB12498] DB01281|Abatacept CD80;CD86 DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0007165| signal transduction CD86;CXCR4 GO:0016032| viral reproduction CD80;CD86;CXCR4 26922:[DB01281 DB07388] DB01281|Abatacept CD80;CD86 DB07388|ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2;NOS3 common genes common pathways 26923:[DB01281 DB00827] DB01281|Abatacept CD80;CD86 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways 26924:[DB01281 DB01632] DB01281|Abatacept CD80;CD86 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0016032| viral reproduction CD80;CD86;UCKL1 26925:[DB01281 DB00562] DB01281|Abatacept CD80;CD86 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways 26926:[DB01281 DB02821] DB01281|Abatacept CD80;CD86 DB02821|Canaline OAT common genes common pathways 26927:[DB01281 DB01370] DB01281|Abatacept CD80;CD86 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade APP;CD86;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation APP;CD80 26928:[DB01281 DB04818] DB01281|Abatacept CD80;CD86 DB04818|Iproniazid MAOB;CYP2D6;CYP2C9 common genes common pathways 26929:[DB01281 DB02207] DB01281|Abatacept CD80;CD86 DB02207|7-Nitroindazole NOS3;NOS2 common genes common pathways 26930:[DB01281 DB08905] DB01281|Abatacept CD80;CD86 DB08905|Formestane CYP3A4 common genes common pathways 26931:[DB01281 DB11294] DB01281|Abatacept CD80;CD86 DB11294|Coccidioides immitis spherule HLA-A;HLA-A;HLA-B common genes common pathways GO:0016032| viral reproduction CD80;HLA-B;HLA-A;CD86 GO:0006955| immune response CD86;HLA-A;HLA-B GO:0002376| immune system process HLA-B;CD86;HLA-A 26932:[DB01281 DB08800] DB01281|Abatacept CD80;CD86 DB08800|Chloropyramine HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 26933:[DB01281 DB07239] DB01281|Abatacept CD80;CD86 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0031295| T cell costimulation CD80;CD86;DPP4 GO:0008284| positive regulation of cell proliferation CD86;DPP4 26934:[DB01281 DB08384] DB01281|Abatacept CD80;CD86 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways GO:0007165| signal transduction PDE10A;CD86 26935:[DB01281 DB05398] DB01281|Abatacept CD80;CD86 DB05398|C31G CD9 common genes common pathways 26936:[DB01281 DB00054] DB01281|Abatacept CD80;CD86 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:0002376| immune system process C1QA;C1S;C1QC;FCGR1A;FCGR2A;CD86;C1QB;C1R GO:0007165| signal transduction FCGR2B;CD86;FCGR1A;FCGR2C GO:0046718| entry of virus into host cell CD80;CD86;ITGB3 GO:0016032| viral reproduction CD80;FCGR2B;ITGB3;CD86 GO:0006955| immune response FCGR3A;FCGR2C;VTN;C1QC;CD86;FCGR1A;C1R;FCGR2B;FCGR3B GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;CD80;VTN 26937:[DB01281 DB01277] DB01281|Abatacept CD80;CD86 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0035556| intracellular signal transduction INSR;CD80 GO:0006955| immune response IGF1R;CD86 GO:0007165| signal transduction IGF1R;IGF2R;CD86 GO:0008284| positive regulation of cell proliferation IGF1R;INSR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;INSR;CD80 GO:0045893| positive regulation of transcription, DNA-dependent INSR;CD86;CD80 26938:[DB01281 DB02746] DB01281|Abatacept CD80;CD86 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0007165| signal transduction PPARG;CD86;ESR2;PGR;ESR1 GO:0016032| viral reproduction CD80;CD86;RXRA GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARD;ESR1;PPARA;PPARG;RXRA;ESR2;CD86 GO:0008284| positive regulation of cell proliferation PPARD;CD86 26939:[DB01281 DB02175] DB01281|Abatacept CD80;CD86 DB02175|Malonic acid panD;SRC;SNRPA common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0002376| immune system process SRC;CD86 GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction CD86;CD80;SRC GO:0035556| intracellular signal transduction CD80;SRC GO:0007165| signal transduction SRC;CD86 26940:[DB01281 DB00892] DB01281|Abatacept CD80;CD86 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways 26941:[DB01281 DB02558] DB01281|Abatacept CD80;CD86 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways 26942:[DB01281 DB08530] DB01281|Abatacept CD80;CD86 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation DPP4;CD86;CD80 26943:[DB01281 DB13925] DB01281|Abatacept CD80;CD86 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways GO:0007165| signal transduction SSTR2;CD86 26944:[DB01281 DB14060] DB01281|Abatacept CD80;CD86 DB14060|NS-398 PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26945:[DB01281 DB07468] DB01281|Abatacept CD80;CD86 DB07468|(3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 26946:[DB01281 DB01180] DB01281|Abatacept CD80;CD86 DB01180|Rescinnamine ACE common genes common pathways 26947:[DB01281 DB00310] DB01281|Abatacept CD80;CD86 DB00310|Chlorthalidone SLC12A1 common genes common pathways 26948:[DB01281 DB02170] DB01281|Abatacept CD80;CD86 DB02170|1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 GO:0007165| signal transduction CD86;CSNK2A1 26949:[DB01281 DB00913] DB01281|Abatacept CD80;CD86 DB00913|Anileridine OPRM1 common genes common pathways GO:0007165| signal transduction OPRM1;CD86 26950:[DB01281 DB08848] DB01281|Abatacept CD80;CD86 DB08848|Guvacine SLC6A13;SLC6A1;SLC6A11;SLC6A12 common genes common pathways 26951:[DB01281 DB00975] DB01281|Abatacept CD80;CD86 DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0007165| signal transduction PDE5A;CD86;PDE4A;PDE10A;RCAN1 26952:[DB01281 DB02512] DB01281|Abatacept CD80;CD86 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways 26953:[DB01281 DB12589] DB01281|Abatacept CD80;CD86 DB12589|Dacetuzumab CD40 common genes common pathways GO:0002376| immune system process CD86;CD40 GO:0006955| immune response CD86;CD40 26954:[DB01281 DB07106] DB01281|Abatacept CD80;CD86 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways 26955:[DB01281 DB09097] DB01281|Abatacept CD80;CD86 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways GO:0007165| signal transduction DRD5;DRD1;DRD2;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 26956:[DB01281 DB08629] DB01281|Abatacept CD80;CD86 DB08629|N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE ATP5B common genes common pathways 26957:[DB01281 DB04886] DB01281|Abatacept CD80;CD86 DB04886|Calanolide A CYP3A4 common genes common pathways 26958:[DB01281 DB05075] DB01281|Abatacept CD80;CD86 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0031295| T cell costimulation CSK;CD86;CD80 GO:0002376| immune system process CD86;CSK GO:0002250| adaptive immune response CSK;CD86 GO:0008284| positive regulation of cell proliferation FLT4;KDR;CD86;FLT1 GO:0016032| viral reproduction CD86;KDR;CD80 26959:[DB01281 DB04736] DB01281|Abatacept CD80;CD86 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways GO:0002376| immune system process PGLYRP3;CD86 26960:[DB01281 DB05364] DB01281|Abatacept CD80;CD86 DB05364|ROX-888 CCL3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CCL3;CD80 GO:0006955| immune response CCL3;CD86 26961:[DB01281 DB05095] DB01281|Abatacept CD80;CD86 DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 26962:[DB01281 DB00067] DB01281|Abatacept CD80;CD86 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0007165| signal transduction AVPR2;CD86;AVPR1B;AVPR1A GO:0008284| positive regulation of cell proliferation CD86;AVPR2;AVPR1A 26963:[DB01281 DB03216] DB01281|Abatacept CD80;CD86 DB03216|(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine AHCY common genes common pathways 26964:[DB01281 DB05204] DB01281|Abatacept CD80;CD86 DB05204|XL418 BTK common genes common pathways GO:0035556| intracellular signal transduction BTK;CD80 GO:0002250| adaptive immune response BTK;CD86 GO:0002376| immune system process BTK;CD86 26965:[DB01281 DB02902] DB01281|Abatacept CD80;CD86 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways 26966:[DB01281 DB07116] DB01281|Abatacept CD80;CD86 DB07116|1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE UNG common genes common pathways GO:0016032| viral reproduction CD80;UNG;CD86 26967:[DB01281 DB00789] DB01281|Abatacept CD80;CD86 DB00789|Gadopentetic acid PGD common genes common pathways 26968:[DB01281 DB07646] DB01281|Abatacept CD80;CD86 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways 26969:[DB01281 DB04599] DB01281|Abatacept CD80;CD86 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CD86 GO:0007165| signal transduction GRIA2;HTR2A;CD86;DRD2 GO:0046718| entry of virus into host cell HTR2A;CD80;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 26970:[DB01281 DB00282] DB01281|Abatacept CD80;CD86 DB00282|Pamidronate FDPS common genes common pathways GO:0016032| viral reproduction FDPS;CD80;CD86 26971:[DB01281 DB06831] DB01281|Abatacept CD80;CD86 DB06831|2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE PIK3CG;PIK3CD common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CG;PIK3CD;CD86;CD80 GO:0002250| adaptive immune response CD86;PIK3CG;PIK3CD GO:0046854| phosphatidylinositol phosphorylation CD86;PIK3CG;PIK3CD;CD80 GO:0002376| immune system process PIK3CD;PIK3CG;CD86 GO:0007165| signal transduction CD86;PIK3CD 26972:[DB01281 DB00935] DB01281|Abatacept CD80;CD86 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;CD86;ADRA1D GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0007165| signal transduction ADRA1A;CD86;ADRA2A;ADRA1D;ADRA1B;ADRA2B;ADRA2C 26973:[DB01281 DB05016] DB01281|Abatacept CD80;CD86 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways 26974:[DB01281 DB01341] DB01281|Abatacept CD80;CD86 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways 26975:[DB01281 DB02183] DB01281|Abatacept CD80;CD86 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways GO:0007165| signal transduction HINT1;CD86 26976:[DB01281 DB00129] DB01281|Abatacept CD80;CD86 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways GO:0002250| adaptive immune response ARG1;ARG2;CD86 GO:0002376| immune system process ARG1;ARG2;CD86 26977:[DB01281 DB05467] DB01281|Abatacept CD80;CD86 DB05467|R667 RARG common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;RARG 26978:[DB01281 DB00519] DB01281|Abatacept CD80;CD86 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes common pathways 26979:[DB01281 DB03397] DB01281|Abatacept CD80;CD86 DB03397|Uridine-Diphosphate-N-Acetylglucosamine glmU;UAP1;murA;GALE;glmU;EXTL2;MGAT1 common genes common pathways 26980:[DB01281 DB01908] DB01281|Abatacept CD80;CD86 DB01908|RU85493 SRC common genes common pathways GO:0035556| intracellular signal transduction CD80;SRC GO:0016032| viral reproduction CD86;CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0007165| signal transduction CD86;SRC GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;SRC GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation CD86;SRC;CD80 26981:[DB01281 DB06962] DB01281|Abatacept CD80;CD86 DB06962|(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone TPSB2 common genes common pathways 26982:[DB01281 DB06928] DB01281|Abatacept CD80;CD86 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways 26983:[DB01281 DB06376] DB01281|Abatacept CD80;CD86 DB06376|CHGN111 CLK1 common genes common pathways 26984:[DB01281 DB12248] DB01281|Abatacept CD80;CD86 DB12248|Tulobuterol ADRB2 common genes common pathways GO:0007165| signal transduction ADRB2;CD86 26985:[DB01281 DB02518] DB01281|Abatacept CD80;CD86 DB02518|N-Acetylalanine AKR1B1 common genes common pathways 26986:[DB01281 DB01084] DB01281|Abatacept CD80;CD86 DB01084|Emedastine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 26987:[DB01281 DB11327] DB01281|Abatacept CD80;CD86 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 26988:[DB01281 DB06083] DB01281|Abatacept CD80;CD86 DB06083|Tapinarof IL12B;IL2;IL6;CXCL8 common genes common pathways GO:0007165| signal transduction CXCL8;CD86 GO:0035556| intracellular signal transduction CXCL8;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;CD80 GO:0006955| immune response IL2;CD86;IL6;CXCL8 GO:0002376| immune system process IL2;CD86 GO:0008284| positive regulation of cell proliferation IL2;CD86;IL6 GO:0045893| positive regulation of transcription, DNA-dependent IL6;CD86;CD80 GO:0002250| adaptive immune response CD86;IL2 26989:[DB01281 DB00626] DB01281|Abatacept CD80;CD86 DB00626|Bacitracin IDE;A2M common genes common pathways GO:0016032| viral reproduction IDE;CD86;CD80 GO:0046718| entry of virus into host cell IDE;CD86;CD80 26990:[DB01281 DB07288] DB01281|Abatacept CD80;CD86 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;FLT1 26991:[DB01281 DB02445] DB01281|Abatacept CD80;CD86 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 26992:[DB01281 DB00583] DB01281|Abatacept CD80;CD86 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways 26993:[DB01281 DB05944] DB01281|Abatacept CD80;CD86 DB05944|Varlitinib ERBB2;EGFR common genes common pathways GO:0008284| positive regulation of cell proliferation EGFR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;EGFR;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;EGFR;ERBB2;CD80 GO:0046854| phosphatidylinositol phosphorylation ERBB2;CD80;CD86;EGFR GO:0035556| intracellular signal transduction CD80;EGFR GO:0046718| entry of virus into host cell CD80;EGFR;CD86 GO:0007165| signal transduction ERBB2;CD86;EGFR 26994:[DB01281 DB05009] DB01281|Abatacept CD80;CD86 DB05009|Apadenoson ADORA2A common genes common pathways GO:0007165| signal transduction ADORA2A;CD86 26995:[DB01281 DB12518] DB01281|Abatacept CD80;CD86 DB12518|Raclopride DRD2 common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction CD86;DRD2 26996:[DB01281 DB05281] DB01281|Abatacept CD80;CD86 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BCL2 26997:[DB01281 DB11311] DB01281|Abatacept CD80;CD86 DB11311|Prothrombin FGA;FGB;F13A1;CPB2;F10 common genes common pathways GO:0007165| signal transduction FGA;CD86;FGB GO:0002250| adaptive immune response FGB;FGA;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 GO:0002376| immune system process FGB;CD86;FGA 26998:[DB01281 DB08391] DB01281|Abatacept CD80;CD86 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0007165| signal transduction PDE10A;CD86 26999:[DB01281 DB07775] DB01281|Abatacept CD80;CD86 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways 27000:[DB01281 DB06439] DB01281|Abatacept CD80;CD86 DB06439|Tyloxapol LPL common genes common pathways 27001:[DB01281 DB00158] DB01281|Abatacept CD80;CD86 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0008284| positive regulation of cell proliferation FOLR2;CD86 27002:[DB01281 DB12702] DB01281|Abatacept CD80;CD86 DB12702|Velusetrag HTR4 common genes common pathways GO:0007165| signal transduction CD86;HTR4 27003:[DB01281 DB03554] DB01281|Abatacept CD80;CD86 DB03554|5-Iodouracil DPYD common genes common pathways 27004:[DB01281 DB08473] DB01281|Abatacept CD80;CD86 DB08473|5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole CSNK2A1 common genes common pathways GO:0007165| signal transduction CSNK2A1;CD86 GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 27005:[DB01281 DB08056] DB01281|Abatacept CD80;CD86 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;LCK;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;LCK;CD86 GO:0031295| T cell costimulation LCK;CD86;CD80 GO:0016032| viral reproduction CD80;LCK;CD86 27006:[DB01281 DB00376] DB01281|Abatacept CD80;CD86 DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CD86;CHRM4;CHRM3;CHRM1;CHRM2;CHRM5 27007:[DB01281 DB00901] DB01281|Abatacept CD80;CD86 DB00901|Bitolterol ADRB2 common genes common pathways GO:0007165| signal transduction CD86;ADRB2 27008:[DB01281 DB00692] DB01281|Abatacept CD80;CD86 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;CD86;ADRA1D GO:0007165| signal transduction ADRA1D;CD86;ADRA2A;ADRA1A;ADRA1B GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A 27009:[DB01281 DB07167] DB01281|Abatacept CD80;CD86 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways GO:0002376| immune system process CSF1R;CD86 GO:0008284| positive regulation of cell proliferation CSF1R;CD86 GO:0007165| signal transduction CSF1R;CD86 27010:[DB01281 DB08341] DB01281|Abatacept CD80;CD86 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTK2B GO:0002250| adaptive immune response CD86;PTK2B GO:0002376| immune system process PTK2B;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;PTK2B GO:0007165| signal transduction CD86;PTK2B 27011:[DB01281 DB13627] DB01281|Abatacept CD80;CD86 DB13627|Oxolinic acid CYP1A2 common genes common pathways 27012:[DB01281 DB05036] DB01281|Abatacept CD80;CD86 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways GO:0007165| signal transduction PTGES3;CD86 27013:[DB01281 DB07969] DB01281|Abatacept CD80;CD86 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways GO:0046854| phosphatidylinositol phosphorylation MET;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade MET;CD80;CD86 GO:0007165| signal transduction CD86;MET 27014:[DB01281 DB03902] DB01281|Abatacept CD80;CD86 DB03902|Oxalic Acid SRC;SLCO2B1;SLC22A8 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0016032| viral reproduction SRC;CD80;CD86 GO:0035556| intracellular signal transduction CD80;SRC GO:0007165| signal transduction SRC;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;SRC GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;SRC GO:0031295| T cell costimulation SRC;CD80;CD86 GO:0002376| immune system process CD86;SRC 27015:[DB01281 DB04249] DB01281|Abatacept CD80;CD86 DB04249|Zinc Substituted Heme C CYCS common genes common pathways 27016:[DB01281 DB01890] DB01281|Abatacept CD80;CD86 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways GO:0007165| signal transduction IGF1;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;IGF1 GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CD80;IGF1;CD86 GO:0008284| positive regulation of cell proliferation IGF1;CD86 27017:[DB01281 DB08237] DB01281|Abatacept CD80;CD86 DB08237|2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) POLK common genes common pathways 27018:[DB01281 DB14014] DB01281|Abatacept CD80;CD86 DB14014|SR-9011 NR1D2;NR1D1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;NR1D1;NR1D2;CD80 27019:[DB01281 DB00535] DB01281|Abatacept CD80;CD86 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 27020:[DB01281 DB05070] DB01281|Abatacept CD80;CD86 DB05070|ADX10059 GRM5 common genes common pathways GO:0007165| signal transduction GRM5;CD86 27021:[DB01281 DB05481] DB01281|Abatacept CD80;CD86 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways 27022:[DB01281 DB14520] DB01281|Abatacept CD80;CD86 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CALR GO:0046718| entry of virus into host cell CD80;TFRC;ITGB3;CD86 GO:0016032| viral reproduction CD86;ITGB3;TFRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ITGB3;CD80 27023:[DB01281 DB04991] DB01281|Abatacept CD80;CD86 DB04991|XL784 ADAM10 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ADAM10 27024:[DB01281 DB00723] DB01281|Abatacept CD80;CD86 DB00723|Methoxamine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A GO:0007165| signal transduction CD86;ADRA1A;ADRA1D;ADRA1B GO:0008284| positive regulation of cell proliferation CD86;ADRA1D 27025:[DB01281 DB00025] DB01281|Abatacept CD80;CD86 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 GO:0008284| positive regulation of cell proliferation CALR;CD86;F2 27026:[DB01281 DB07086] DB01281|Abatacept CD80;CD86 DB07086|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL NCOA2;ESR1 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 27027:[DB01281 DB01365] DB01281|Abatacept CD80;CD86 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007165| signal transduction ADRA1B;ADRB2;ADRA2B;ADRA2C;ADRB3;CD86;ADRA2A;ADRA1A;ADRB1;ADRA1D GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A GO:0008284| positive regulation of cell proliferation CD86;ADRA2A;ADRA1D 27028:[DB01281 DB01157] DB01281|Abatacept CD80;CD86 DB01157|Trimetrexate DHFR common genes common pathways 27029:[DB01281 DB07853] DB01281|Abatacept CD80;CD86 DB07853|[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE SLK;CAMK2D;STK26 common genes common pathways 27030:[DB01281 DB05085] DB01281|Abatacept CD80;CD86 DB05085|TM30339 NPY4R common genes common pathways GO:0007165| signal transduction NPY4R;CD86 27031:[DB01281 DB09211] DB01281|Abatacept CD80;CD86 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways GO:0006955| immune response CD86;PTGER4 GO:0007165| signal transduction PTGER4;CD86;PTGER3;PTGER1;PTGER2 27032:[DB01281 DB01011] DB01281|Abatacept CD80;CD86 DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways GO:0006955| immune response CYP11B1;CD86 27033:[DB01281 DB00219] DB01281|Abatacept CD80;CD86 DB00219|Oxyphenonium CHRM1 common genes common pathways GO:0007165| signal transduction CHRM1;CD86 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 27034:[DB01281 DB13928] DB01281|Abatacept CD80;CD86 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0046718| entry of virus into host cell CD80;CD86;DPP4 GO:0007165| signal transduction CD86;GLP1R GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD80;CD86;DPP4 27035:[DB01281 DB06771] DB01281|Abatacept CD80;CD86 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways 27036:[DB01281 DB06800] DB01281|Abatacept CD80;CD86 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways GO:0007165| signal transduction CD86;OPRK1;OPRM1 GO:0006955| immune response OPRK1;CD86 27037:[DB01281 DB13139] DB01281|Abatacept CD80;CD86 DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0007165| signal transduction CD86;ADRB2 27038:[DB01281 DB03347] DB01281|Abatacept CD80;CD86 DB03347|Triethyl Phosphate TP53 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;TP53;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;TP53 GO:0016032| viral reproduction CD80;TP53;CD86 27039:[DB01281 DB05146] DB01281|Abatacept CD80;CD86 DB05146|XL820 KDR;KIT;PDGFRA;PDGFRB common genes common pathways GO:0035556| intracellular signal transduction CD80;KIT;PDGFRB GO:0016032| viral reproduction CD80;KDR;PDGFRA;CD86 GO:0007165| signal transduction KIT;PDGFRB;CD86 GO:0008284| positive regulation of cell proliferation PDGFRB;KDR;PDGFRA;CD86;KIT GO:0051897| positive regulation of protein kinase B signaling cascade KIT;CD80;PDGFRA;CD86;PDGFRB GO:0046854| phosphatidylinositol phosphorylation PDGFRB;PDGFRA;CD86;CD80;KIT 27040:[DB01281 DB01152] DB01281|Abatacept CD80;CD86 DB01152|Candicidin CYP3A4 common genes common pathways 27041:[DB01281 DB00354] DB01281|Abatacept CD80;CD86 DB00354|Buclizine HRH1;CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction HRH1;CHRM1;CD86 27042:[DB01281 DB04831] DB01281|Abatacept CD80;CD86 DB04831|Tienilic acid CYP2C9 common genes common pathways 27043:[DB01281 DB05399] DB01281|Abatacept CD80;CD86 DB05399|Succinobucol VCAM1 common genes common pathways GO:0016032| viral reproduction CD86;VCAM1;CD80 27044:[DB01281 DB02698] DB01281|Abatacept CD80;CD86 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways 27045:[DB01281 DB08342] DB01281|Abatacept CD80;CD86 DB08342|S-PALMITOYL-L-CYSTEINE TRAPPC6A;TRAPPC3;TRAPPC6B;TRAPPC5;TRAPPC4;TRAPPC1 common genes common pathways 27046:[DB01281 DB02918] DB01281|Abatacept CD80;CD86 DB02918|Zardaverine PDE4D common genes common pathways GO:0007165| signal transduction CD86;PDE4D 27047:[DB01281 DB01752] DB01281|Abatacept CD80;CD86 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways GO:0008284| positive regulation of cell proliferation PRMT1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;SETD7 27048:[DB01281 DB08610] DB01281|Abatacept CD80;CD86 DB08610|N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE PDK2 common genes common pathways 27049:[DB01281 DB01970] DB01281|Abatacept CD80;CD86 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways GO:0007165| signal transduction PDE3B;CD86 27050:[DB01281 DB07162] DB01281|Abatacept CD80;CD86 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways GO:0002376| immune system process CD86;JAK2 GO:0002250| adaptive immune response CD86;JAK2 GO:0008284| positive regulation of cell proliferation CD86;JAK2 GO:0007165| signal transduction JAK2;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation JAK2;CD80 GO:0035556| intracellular signal transduction JAK2;CD80 27051:[DB01281 DB01419] DB01281|Abatacept CD80;CD86 DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 27052:[DB01281 DB00887] DB01281|Abatacept CD80;CD86 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0046718| entry of virus into host cell CD86;SLC10A1;CD80 GO:0016032| viral reproduction CD80;SLC10A1;CD86 GO:0008284| positive regulation of cell proliferation CD86;PTGS2 27053:[DB01281 DB00756] DB01281|Abatacept CD80;CD86 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 GO:0007165| signal transduction ESR1;CD86 27054:[DB01281 DB04450] DB01281|Abatacept CD80;CD86 DB04450|Heptyl 1-Thiohexopyranoside RHO;fpr;acpP common genes common pathways GO:0007165| signal transduction RHO;CD86 27055:[DB01281 DB07626] DB01281|Abatacept CD80;CD86 DB07626|4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 27056:[DB01281 DB01689] DB01281|Abatacept CD80;CD86 DB01689|Inhibitor Idd 384 AKR1B1 common genes common pathways 27057:[DB01281 DB09325] DB01281|Abatacept CD80;CD86 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 27058:[DB01281 DB00115] DB01281|Abatacept CD80;CD86 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways 27059:[DB01281 DB08257] DB01281|Abatacept CD80;CD86 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways 27060:[DB01281 DB04721] DB01281|Abatacept CD80;CD86 DB04721|N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 GO:0007165| signal transduction CSNK2A1;CD86 27061:[DB01281 DB07991] DB01281|Abatacept CD80;CD86 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 GO:0007165| signal transduction ESR1;CD86 27062:[DB01281 DB06635] DB01281|Abatacept CD80;CD86 DB06635|Otamixaban F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 27063:[DB01281 DB05298] DB01281|Abatacept CD80;CD86 DB05298|Tetomilast PDE4D common genes common pathways GO:0007165| signal transduction CD86;PDE4D 27064:[DB01281 DB07030] DB01281|Abatacept CD80;CD86 DB07030|(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID AKR1B1 common genes common pathways 27065:[DB01281 DB05562] DB01281|Abatacept CD80;CD86 DB05562|Naluzotan HTR1A common genes common pathways GO:0007165| signal transduction CD86;HTR1A GO:0008284| positive regulation of cell proliferation CD86;HTR1A 27066:[DB01281 DB04339] DB01281|Abatacept CD80;CD86 DB04339|Carbocisteine GSTP1 common genes common pathways 27067:[DB01281 DB05101] DB01281|Abatacept CD80;CD86 DB05101|Matuzumab EGFR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;EGFR;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;EGFR;CD86 GO:0008284| positive regulation of cell proliferation EGFR;CD86 GO:0046854| phosphatidylinositol phosphorylation EGFR;CD86;CD80 GO:0035556| intracellular signal transduction EGFR;CD80 GO:0046718| entry of virus into host cell EGFR;CD86;CD80 GO:0007165| signal transduction EGFR;CD86 27068:[DB01281 DB06454] DB01281|Abatacept CD80;CD86 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;DRD3;CD86 GO:0007165| signal transduction DRD3;CD86;DRD2;HTR1A GO:0035556| intracellular signal transduction DRD2;CD80 27069:[DB01281 DB14126] DB01281|Abatacept CD80;CD86 DB14126|Tenofovir ABCB1 common genes common pathways 27070:[DB01281 DB08389] DB01281|Abatacept CD80;CD86 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways GO:0007165| signal transduction CD86;PDE10A 27071:[DB01281 DB00677] DB01281|Abatacept CD80;CD86 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways 27072:[DB01281 DB05806] DB01281|Abatacept CD80;CD86 DB05806|Cositecan TOP1 common genes common pathways GO:0016032| viral reproduction CD86;TOP1;CD80 27073:[DB01281 DB04633] DB01281|Abatacept CD80;CD86 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways 27074:[DB01281 DB13926] DB01281|Abatacept CD80;CD86 DB13926|Cenegermin NTRK1 common genes common pathways 27075:[DB01281 DB00776] DB01281|Abatacept CD80;CD86 DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes common pathways 27076:[DB01281 DB11323] DB01281|Abatacept CD80;CD86 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 27077:[DB01281 DB03957] DB01281|Abatacept CD80;CD86 DB03957|SP2456 IL2 common genes common pathways GO:0006955| immune response IL2;CD86 GO:0002250| adaptive immune response CD86;IL2 GO:0008284| positive regulation of cell proliferation CD86;IL2 GO:0002376| immune system process CD86;IL2 27078:[DB01281 DB14544] DB01281|Abatacept CD80;CD86 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0045627| positive regulation of T-helper 1 cell differentiation ANXA1;CD80 GO:0006955| immune response CYP11B1;CD86 GO:0007165| signal transduction CD86;ANXA1;NR3C1 GO:0002250| adaptive immune response ANXA1;CD86 GO:0002376| immune system process ANXA1;CD86 27079:[DB01281 DB14481] DB01281|Abatacept CD80;CD86 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0008284| positive regulation of cell proliferation S100A13;CASR;S100B;CD86;CIB1;CALR GO:0016032| viral reproduction CD80;SLC20A2;CD86 GO:0035556| intracellular signal transduction CAPS;CD80 GO:0046718| entry of virus into host cell CD86;SLC20A2;CD80 GO:0007165| signal transduction SLC20A1;SRI;SPARC;CASR;S100A6;CD86;CACNA1I 27080:[DB01281 DB06401] DB01281|Abatacept CD80;CD86 DB06401|Bazedoxifene ESR1;ESR2;UGT1A8;UGT1A10 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR2;ESR1;CD80 GO:0007165| signal transduction ESR2;CD86;ESR1 27081:[DB01281 DB08102] DB01281|Abatacept CD80;CD86 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways 27082:[DB01281 DB07020] DB01281|Abatacept CD80;CD86 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways 27083:[DB01281 DB05739] DB01281|Abatacept CD80;CD86 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;AGTR2 GO:0008284| positive regulation of cell proliferation CD86;AGTR2 GO:0035556| intracellular signal transduction CD80;AGTR2 GO:0007165| signal transduction CD86;AGTR2;AGTR1 27084:[DB01281 DB09308] DB01281|Abatacept CD80;CD86 DB09308|Solithromycin CYP3A4 common genes common pathways 27085:[DB01281 DB08927] DB01281|Abatacept CD80;CD86 DB08927|Amperozide HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0007165| signal transduction HTR2A;CD86 27086:[DB01281 DB05966] DB01281|Abatacept CD80;CD86 DB05966|TAS-108 ESR1;ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86;ESR2 GO:0007165| signal transduction ESR2;CD86;ESR1 27087:[DB01281 DB00017] DB01281|Abatacept CD80;CD86 DB00017|Salmon Calcitonin CALCR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;CALCR GO:0007165| signal transduction CD86;CALCR 27088:[DB01281 DB04200] DB01281|Abatacept CD80;CD86 DB04200|Matairesinol DHRS4L2 common genes common pathways 27089:[DB01281 DB08263] DB01281|Abatacept CD80;CD86 DB08263|N-(carboxycarbonyl)-D-phenylalanine HIF1AN common genes common pathways 27090:[DB01281 DB05266] DB01281|Abatacept CD80;CD86 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0007165| signal transduction CD86;PDE4B;PDE4C;PDE3A;PDE4D;PDE4A 27091:[DB01281 DB08487] DB01281|Abatacept CD80;CD86 DB08487|3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 27092:[DB01281 DB07306] DB01281|Abatacept CD80;CD86 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways 27093:[DB01281 DB01427] DB01281|Abatacept CD80;CD86 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;TNF;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;TNF GO:0006955| immune response TNF;CD86 GO:0007165| signal transduction PDE3A;PDE4B;CD86 27094:[DB01281 DB12319] DB01281|Abatacept CD80;CD86 DB12319|Benzbromarone CYP2C9;CYP2C19;CYP2C19;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways 27095:[DB01281 DB05488] DB01281|Abatacept CD80;CD86 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways 27096:[DB01281 DB03577] DB01281|Abatacept CD80;CD86 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways 27097:[DB01281 DB06525] DB01281|Abatacept CD80;CD86 DB06525|Ganstigmine ACHE common genes common pathways 27098:[DB01281 DB00173] DB01281|Abatacept CD80;CD86 DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0035556| intracellular signal transduction CD80;SRPK2 GO:0008284| positive regulation of cell proliferation SRPK2;CD86 27099:[DB01281 DB00927] DB01281|Abatacept CD80;CD86 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0007165| signal transduction CD86;HRH2 GO:0006955| immune response CD86;HRH2 27100:[DB01281 DB09006] DB01281|Abatacept CD80;CD86 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARD;PPARA;CD86;PPARG GO:0008284| positive regulation of cell proliferation CD86;PPARD GO:0007165| signal transduction PPARG;CD86 27101:[DB01281 DB00979] DB01281|Abatacept CD80;CD86 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0007165| signal transduction CHRM1;CD86 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 27102:[DB01281 DB07577] DB01281|Abatacept CD80;CD86 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways 27103:[DB01281 DB07489] DB01281|Abatacept CD80;CD86 DB07489|4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium CSNK1G3 common genes common pathways GO:0007165| signal transduction CSNK1G3;CD86 27104:[DB01281 DB02811] DB01281|Abatacept CD80;CD86 DB02811|Diethylphosphono Group BCHE;fbpC;BCHE common genes common pathways 27105:[DB01281 DB04847] DB01281|Abatacept CD80;CD86 DB04847|Roxadustat EGLN1;EGLN2;EGLN3 common genes common pathways 27106:[DB01281 DB09369] DB01281|Abatacept CD80;CD86 DB09369|Polyestradiol phosphate ESR1 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 27107:[DB01281 DB08734] DB01281|Abatacept CD80;CD86 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways 27108:[DB01281 DB09116] DB01281|Abatacept CD80;CD86 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways 27109:[DB01281 DB09347] DB01281|Abatacept CD80;CD86 DB09347|Acetrizoic acid ALB common genes common pathways 27110:[DB01281 DB05029] DB01281|Abatacept CD80;CD86 DB05029|Lancovutide PLA2G4A common genes common pathways 27111:[DB01281 DB13520] DB01281|Abatacept CD80;CD86 DB13520|Metergoline SCN2A common genes common pathways 27112:[DB01281 DB08369] DB01281|Abatacept CD80;CD86 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways 27113:[DB01281 DB08348] DB01281|Abatacept CD80;CD86 DB08348|N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE EEF2;PARP3;PARP15 common genes common pathways 27114:[DB01281 DB05876] DB01281|Abatacept CD80;CD86 DB05876|PDE4 PDE4A common genes common pathways GO:0007165| signal transduction CD86;PDE4A 27115:[DB01281 DB06441] DB01281|Abatacept CD80;CD86 DB06441|Cangrelor P2RY12 common genes common pathways GO:0007165| signal transduction CD86;P2RY12 27116:[DB01281 DB02431] DB01281|Abatacept CD80;CD86 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways 27117:[DB01281 DB09059] DB01281|Abatacept CD80;CD86 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0008284| positive regulation of cell proliferation AVPR2;CD86;AVPR1A GO:0007165| signal transduction AVPR1A;OXTR;AVPR2;CD86;AVPR1B 27118:[DB01281 DB07902] DB01281|Abatacept CD80;CD86 DB07902|TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE METAP1 common genes common pathways 27119:[DB01281 DB08805] DB01281|Abatacept CD80;CD86 DB08805|Metiamide HRH2 common genes common pathways GO:0006955| immune response HRH2;CD86 GO:0007165| signal transduction HRH2;CD86 27120:[DB01281 DB08072] DB01281|Abatacept CD80;CD86 DB08072|4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 27121:[DB01281 DB07221] DB01281|Abatacept CD80;CD86 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways 27122:[DB01281 DB01956] DB01281|Abatacept CD80;CD86 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0007165| signal transduction GABRA5;GABRD;GABRP;CD86;GABRE;GABBR1;GABRB1;GABRQ;GABRA6;GABRB3 27123:[DB01281 DB02889] DB01281|Abatacept CD80;CD86 DB02889|4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose AMY2A;AMY2A common genes common pathways 27124:[DB01281 DB01780] DB01281|Abatacept CD80;CD86 DB01780|Fusicoccin YWHAE common genes common pathways GO:0016032| viral reproduction CD86;CD80;YWHAE GO:0035556| intracellular signal transduction YWHAE;CD80 27125:[DB01281 DB04465] DB01281|Abatacept CD80;CD86 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways GO:0002376| immune system process LGALS3;CD86 27126:[DB01281 DB01717] DB01281|Abatacept CD80;CD86 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways 27127:[DB01281 DB07181] DB01281|Abatacept CD80;CD86 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0031295| T cell costimulation CD80;CD86;DPP4 GO:0008284| positive regulation of cell proliferation CD86;DPP4 27128:[DB01281 DB12887] DB01281|Abatacept CD80;CD86 DB12887|Tazemetostat EZH2 common genes common pathways 27129:[DB01281 DB11831] DB01281|Abatacept CD80;CD86 DB11831|Dinitrochlorobenzene MGMT;GSTP1 common genes common pathways 27130:[DB01281 DB02628] DB01281|Abatacept CD80;CD86 DB02628|1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide XIAP common genes common pathways 27131:[DB01281 DB05744] DB01281|Abatacept CD80;CD86 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;CD80 GO:0006955| immune response IL6;CD86;TNF;IL10 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;TNF GO:0045893| positive regulation of transcription, DNA-dependent CD86;IL6;TNF;IL10;CD80 GO:0008284| positive regulation of cell proliferation CD86;IL6 27132:[DB01281 DB08078] DB01281|Abatacept CD80;CD86 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARD;CD86 GO:0008284| positive regulation of cell proliferation CD86;PPARD 27133:[DB01281 DB05867] DB01281|Abatacept CD80;CD86 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 27134:[DB01281 DB12228] DB01281|Abatacept CD80;CD86 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways GO:0007165| signal transduction CD86;CALCB;CALCRL GO:0008284| positive regulation of cell proliferation CD86;CALCRL 27135:[DB01281 DB05003] DB01281|Abatacept CD80;CD86 DB05003|Imexon RRM2;RRM1 common genes common pathways 27136:[DB01281 DB03667] DB01281|Abatacept CD80;CD86 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways 27137:[DB01281 DB02261] DB01281|Abatacept CD80;CD86 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0006955| immune response PTAFR;CD86 GO:0007165| signal transduction CD86;PTAFR 27138:[DB01281 DB02562] DB01281|Abatacept CD80;CD86 DB02562|Quinonoid 7,8-Tetrahydrobiopterin PAH common genes common pathways 27139:[DB01281 DB00209] DB01281|Abatacept CD80;CD86 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CD86;CHRM1 27140:[DB01281 DB01963] DB01281|Abatacept CD80;CD86 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways 27141:[DB01281 DB03359] DB01281|Abatacept CD80;CD86 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways 27142:[DB01281 DB04978] DB01281|Abatacept CD80;CD86 DB04978|SP1049C TOP2A common genes common pathways 27143:[DB01281 DB05205] DB01281|Abatacept CD80;CD86 DB05205|CX157 MAOA common genes common pathways 27144:[DB01281 DB04090] DB01281|Abatacept CD80;CD86 DB04090|RH-1 NQO1 common genes common pathways 27145:[DB01281 DB08293] DB01281|Abatacept CD80;CD86 DB08293|(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways 27146:[DB01281 DB02132] DB01281|Abatacept CD80;CD86 DB02132|Zenarestat AKR1B1 common genes common pathways 27147:[DB01281 DB00761] DB01281|Abatacept CD80;CD86 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways 27148:[DB01281 DB04426] DB01281|Abatacept CD80;CD86 DB04426|Alpha-Methyl-N-Acetyl-D-Glucosamine MBL2 common genes common pathways GO:0002376| immune system process CD86;MBL2 27149:[DB01281 DB07251] DB01281|Abatacept CD80;CD86 DB07251|N'-(3-CHLORO-4-METHOXY-PHENYL)-N-(3,4,5-TRIMETHOXYPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE EPHB4 common genes common pathways 27150:[DB01281 DB04983] DB01281|Abatacept CD80;CD86 DB04983|Denufosol P2RY2 common genes common pathways GO:0007165| signal transduction CD86;P2RY2 27151:[DB01281 DB06137] DB01281|Abatacept CD80;CD86 DB06137|KX-01 SRC common genes common pathways GO:0035556| intracellular signal transduction CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction CD80;SRC;CD86 GO:0007165| signal transduction SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0002376| immune system process SRC;CD86 GO:0031295| T cell costimulation CD86;SRC;CD80 27152:[DB01281 DB04271] DB01281|Abatacept CD80;CD86 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007165| signal transduction PDE4D;CD86 27153:[DB01281 DB11714] DB01281|Abatacept CD80;CD86 DB11714|Durvalumab CD274;CD80 common genes CD80 common pathways GO:0046718| entry of virus into host cell CD80;CD86 GO:0007165| signal transduction CD86;CD274 GO:0045627| positive regulation of T-helper 1 cell differentiation CD80 GO:0006955| immune response CD86;CD274 GO:0016032| viral reproduction CD86;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80 GO:0009967| positive regulation of signal transduction CD80 GO:0035556| intracellular signal transduction CD80 GO:0046854| phosphatidylinositol phosphorylation CD86;CD80 GO:0045086| positive regulation of interleukin-2 biosynthetic process CD80;CD86 GO:0031295| T cell costimulation CD80;CD86;CD274 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80 GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80 27154:[DB01281 DB03753] DB01281|Abatacept CD80;CD86 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways 27155:[DB01281 DB14025] DB01281|Abatacept CD80;CD86 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways 27156:[DB01281 DB14634] DB01281|Abatacept CD80;CD86 DB14634|Fluprednidene acetate CYP3A4 common genes common pathways 27157:[DB01281 DB08455] DB01281|Abatacept CD80;CD86 DB08455|Ro 12-7310 CRABP2 common genes common pathways GO:0007165| signal transduction CD86;CRABP2 27158:[DB01281 DB04690] DB01281|Abatacept CD80;CD86 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes common pathways GO:0016032| viral reproduction CD86;CD80;TOP1 27159:[DB01281 DB03499] DB01281|Abatacept CD80;CD86 DB03499|Malate Ion fumC;glcB;ME2;CS common genes common pathways 27160:[DB01281 DB02486] DB01281|Abatacept CD80;CD86 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways 27161:[DB01281 DB06543] DB01281|Abatacept CD80;CD86 DB06543|Astaxanthin NFKBIA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;NFKBIA GO:0016032| viral reproduction CD86;NFKBIA;CD80 27162:[DB01281 DB06994] DB01281|Abatacept CD80;CD86 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways GO:0031295| T cell costimulation CD80;CD86;DPP4 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0046718| entry of virus into host cell DPP4;CD86;CD80 27163:[DB01281 DB07604] DB01281|Abatacept CD80;CD86 DB07604|(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE ATP2A1 common genes common pathways 27164:[DB01281 DB00154] DB01281|Abatacept CD80;CD86 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 27165:[DB01281 DB00221] DB01281|Abatacept CD80;CD86 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways GO:0007165| signal transduction ADRB2;ADRB1;CD86 27166:[DB01281 DB05227] DB01281|Abatacept CD80;CD86 DB05227|APD791 HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0016032| viral reproduction CD86;HTR2A;CD80 GO:0046718| entry of virus into host cell CD86;CD80;HTR2A GO:0007165| signal transduction CD86;HTR2A 27167:[DB01281 DB05104] DB01281|Abatacept CD80;CD86 DB05104|Asimadoline OPRK1 common genes common pathways GO:0007165| signal transduction CD86;OPRK1 GO:0006955| immune response OPRK1;CD86 27168:[DB01281 DB04297] DB01281|Abatacept CD80;CD86 DB04297|7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide HDAC8;HDAC7 common genes common pathways 27169:[DB01281 DB05013] DB01281|Abatacept CD80;CD86 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways GO:0035556| intracellular signal transduction CD80;PRKCD;PRKCA GO:0007165| signal transduction CD86;PRKCD 27170:[DB01281 DB04803] DB01281|Abatacept CD80;CD86 DB04803|Verdoheme HMOX1 common genes common pathways GO:0035556| intracellular signal transduction HMOX1;CD80 27171:[DB01281 DB05706] DB01281|Abatacept CD80;CD86 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways 27172:[DB01281 DB04487] DB01281|Abatacept CD80;CD86 DB04487|N-Methylleucine CXCL10 common genes common pathways GO:0008284| positive regulation of cell proliferation CXCL10;CD86 GO:0007165| signal transduction CD86;CXCL10 GO:0006955| immune response CXCL10;CD86 27173:[DB01281 DB08167] DB01281|Abatacept CD80;CD86 DB08167|Methylthioninium ACHE common genes common pathways 27174:[DB01281 DB11584] DB01281|Abatacept CD80;CD86 DB11584|Pipradrol DRD1;DRD5 common genes common pathways GO:0007165| signal transduction CD86;DRD1;DRD5 27175:[DB01281 DB08658] DB01281|Abatacept CD80;CD86 DB08658|ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE BCHE common genes common pathways 27176:[DB01281 DB02498] DB01281|Abatacept CD80;CD86 DB02498|Carba-Nicotinamide-Adenine-Dinucleotide PARP1 common genes common pathways 27177:[DB01281 DB02123] DB01281|Abatacept CD80;CD86 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction CD86;SLC10A1;CD80 GO:0046718| entry of virus into host cell CD80;SLC10A1;CD86 27178:[DB01281 DB05890] DB01281|Abatacept CD80;CD86 DB05890|VEGF-AS VEGFA common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA GO:0008284| positive regulation of cell proliferation CD86;VEGFA 27179:[DB01281 DB07779] DB01281|Abatacept CD80;CD86 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 27180:[DB01281 DB12328] DB01281|Abatacept CD80;CD86 DB12328|Cantharidin AHR common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent AHR;CD86;CD80 27181:[DB01281 DB08043] DB01281|Abatacept CD80;CD86 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ABL1 27182:[DB01281 DB00817] DB01281|Abatacept CD80;CD86 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways 27183:[DB01281 DB07623] DB01281|Abatacept CD80;CD86 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways 27184:[DB01281 DB07524] DB01281|Abatacept CD80;CD86 DB07524|N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine PIM1 common genes common pathways 27185:[DB01281 DB07248] DB01281|Abatacept CD80;CD86 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;PTK2;CD80 GO:0008284| positive regulation of cell proliferation PTK2;CD86 27186:[DB01281 DB00900] DB01281|Abatacept CD80;CD86 DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes common pathways GO:0006955| immune response CD86;PNP 27187:[DB01281 DB03951] DB01281|Abatacept CD80;CD86 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 27188:[DB01281 DB05319] DB01281|Abatacept CD80;CD86 DB05319|Oportuzumab monatox EPCAM common genes common pathways GO:0008284| positive regulation of cell proliferation EPCAM;CD86 27189:[DB01281 DB07254] DB01281|Abatacept CD80;CD86 DB07254|N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL]AMINO]PHENYL]METHANESULFONAMIDE EPHB4 common genes common pathways 27190:[DB01281 DB08804] DB01281|Abatacept CD80;CD86 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0007165| signal transduction CD86;AR GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 27191:[DB01281 DB08516] DB01281|Abatacept CD80;CD86 DB08516|(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] MAOB common genes common pathways 27192:[DB01281 DB00665] DB01281|Abatacept CD80;CD86 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0007165| signal transduction CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR GO:0008284| positive regulation of cell proliferation CD86;AR 27193:[DB01281 DB01342] DB01281|Abatacept CD80;CD86 DB01342|Forasartan AGTR1 common genes common pathways GO:0007165| signal transduction CD86;AGTR1 27194:[DB01281 DB05049] DB01281|Abatacept CD80;CD86 DB05049|DDP733 HTR3A common genes common pathways GO:0007165| signal transduction HTR3A;CD86 27195:[DB01281 DB03553] DB01281|Abatacept CD80;CD86 DB03553|Glutaric Acid ilvE;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 27196:[DB01281 DB00605] DB01281|Abatacept CD80;CD86 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PPARD;PTGS2 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;PPARD GO:0035556| intracellular signal transduction CD80;MAPK3 GO:0006955| immune response PTGDR2;CD86 GO:0016032| viral reproduction CD86;CD80;MAPK3 GO:0007165| signal transduction CD86;PTGDR2 27197:[DB01281 DB03796] DB01281|Abatacept CD80;CD86 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CD80;SEC14L2;CD86 GO:0007165| signal transduction LALBA;RHO;CD86 27198:[DB01281 DB07847] DB01281|Abatacept CD80;CD86 DB07847|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 27199:[DB01281 DB05187] DB01281|Abatacept CD80;CD86 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;PPARA;PPARD;CD80 GO:0008284| positive regulation of cell proliferation PPARD;CD86 27200:[DB01281 DB05838] DB01281|Abatacept CD80;CD86 DB05838|OPC-51803 AVPR2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AVPR2 GO:0007165| signal transduction CD86;AVPR2 27201:[DB01281 DB03107] DB01281|Abatacept CD80;CD86 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways 27202:[DB01281 DB03729] DB01281|Abatacept CD80;CD86 DB03729|2-Amino-5-Hydroxy-Benzimidazole PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 27203:[DB01281 DB04454] DB01281|Abatacept CD80;CD86 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways GO:0007165| signal transduction EGF;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;EGF GO:0046854| phosphatidylinositol phosphorylation CD86;CD80;EGF GO:0008284| positive regulation of cell proliferation EGF;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade EGF;CD80;CD86 GO:0045893| positive regulation of transcription, DNA-dependent EGF;CD80;CD86 27204:[DB01281 DB00754] DB01281|Abatacept CD80;CD86 DB00754|Ethotoin SCN5A;NR1I2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CD86;CD80 GO:0007165| signal transduction NR1I2;CD86 27205:[DB01281 DB02705] DB01281|Abatacept CD80;CD86 DB02705|6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 27206:[DB01281 DB06080] DB01281|Abatacept CD80;CD86 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0002376| immune system process CSF1R;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;KIT;CD80 GO:0008284| positive regulation of cell proliferation KIT;CSF1R;FLT3;FLT1;CD86;KDR;FLT4 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;KIT;CD86 GO:0007165| signal transduction CD86;CSF1R;KIT GO:0035556| intracellular signal transduction KIT;CD80 GO:0016032| viral reproduction KDR;CD86;CD80 27207:[DB01281 DB00651] DB01281|Abatacept CD80;CD86 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0007165| signal transduction PDE4D;PDE4A;PDE7B;PDE4B;PDE4C;CD86;PDE7A;ADORA1;ADORA2A 27208:[DB01281 DB06230] DB01281|Abatacept CD80;CD86 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0006955| immune response OPRD1;CD86;OPRK1 GO:0007165| signal transduction OPRK1;CD86;OPRD1;OPRM1 27209:[DB01281 DB06642] DB01281|Abatacept CD80;CD86 DB06642|Bevasiranib VEGFA common genes common pathways GO:0008284| positive regulation of cell proliferation VEGFA;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA 27210:[DB01281 DB11182] DB01281|Abatacept CD80;CD86 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways GO:0002376| immune system process CD86;LTF 27211:[DB01281 DB08708] DB01281|Abatacept CD80;CD86 DB08708|N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine PIM1 common genes common pathways 27212:[DB01281 DB07482] DB01281|Abatacept CD80;CD86 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD86;DPP4;CD80 GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 27213:[DB01281 DB03940] DB01281|Abatacept CD80;CD86 DB03940|Oxamic Acid LDHA;LDHB;SLC16A3 common genes common pathways 27214:[DB01281 DB04770] DB01281|Abatacept CD80;CD86 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways 27215:[DB01281 DB06709] DB01281|Abatacept CD80;CD86 DB06709|Methacholine CHRM3 common genes common pathways GO:0007165| signal transduction CD86;CHRM3 27216:[DB01281 DB02532] DB01281|Abatacept CD80;CD86 DB02532|2,4,6-Triaminoquinazoline DHRS4L1 common genes common pathways 27217:[DB01281 DB00457] DB01281|Abatacept CD80;CD86 DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0007165| signal transduction ADRA2B;ADRA1B;ADRA1D;ADRA1A;CD86;ADRA2A GO:0035556| intracellular signal transduction ADRA1A;CD80;ADRA1B GO:0008284| positive regulation of cell proliferation ADRA2A;CD86;ADRA1D 27218:[DB01281 DB08339] DB01281|Abatacept CD80;CD86 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;CD80 27219:[DB01281 DB05362] DB01281|Abatacept CD80;CD86 DB05362|SSR-126517E F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 27220:[DB01281 DB05069] DB01281|Abatacept CD80;CD86 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways GO:0007165| signal transduction CHRNA9;CD86;CHRNA10 27221:[DB01281 DB14007] DB01281|Abatacept CD80;CD86 DB14007|Pentetic acid SERPINA1 common genes common pathways 27222:[DB01281 DB08526] DB01281|Abatacept CD80;CD86 DB08526|CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE CTSH common genes common pathways GO:0002250| adaptive immune response CD86;CTSH GO:0008284| positive regulation of cell proliferation CTSH;CD86 27223:[DB01281 DB06229] DB01281|Abatacept CD80;CD86 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways GO:0007165| signal transduction HTR2A;ADRA2B;ADRA2C;HRH1;ADRA1B;ADRA1D;CD86;ADRA2A;HTR2B;HTR2C;ADRA1A;DRD2 GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction CD86;HTR2A;CD80 GO:0035556| intracellular signal transduction DRD2;ADRA1A;CD80;ADRA1B GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;HTR2B;CD86;HTR2A 27224:[DB01281 DB04018] DB01281|Abatacept CD80;CD86 DB04018|S-Isopropyl-Isothiourea NOS3 common genes common pathways 27225:[DB01281 DB02551] DB01281|Abatacept CD80;CD86 DB02551|6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 27226:[DB01281 DB05630] DB01281|Abatacept CD80;CD86 DB05630|Sodium stibogluconate TOP1 common genes common pathways GO:0016032| viral reproduction CD86;TOP1;CD80 27227:[DB01281 DB02527] DB01281|Abatacept CD80;CD86 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0035556| intracellular signal transduction PRKAR2B;PRKAR1A;CD80 27228:[DB01281 DB07954] DB01281|Abatacept CD80;CD86 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0007165| signal transduction PDE8A;PDE5A;PDE2A;PDE9A;PDE7A;CD86;PDE4D;PDE3B 27229:[DB01281 DB11363] DB01281|Abatacept CD80;CD86 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways GO:0007165| signal transduction ALK;CD86 27230:[DB01281 DB05168] DB01281|Abatacept CD80;CD86 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways GO:0008284| positive regulation of cell proliferation FOLR2;CD86 27231:[DB01281 DB00984] DB01281|Abatacept CD80;CD86 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AR;CD86 27232:[DB01281 DB11605] DB01281|Abatacept CD80;CD86 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARA;CD80;CD86;NR1I2 GO:0002376| immune system process CD86;NR1H4 GO:0007165| signal transduction CD86;NR1I2;NR1H4 27233:[DB01281 DB08602] DB01281|Abatacept CD80;CD86 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways GO:0007165| signal transduction CD86;PDE7A 27234:[DB01281 DB00522] DB01281|Abatacept CD80;CD86 DB00522|Bentiromide HPN common genes common pathways 27235:[DB01281 DB02004] DB01281|Abatacept CD80;CD86 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD80;CD86;DPP4 27236:[DB01281 DB09301] DB01281|Abatacept CD80;CD86 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;VEGFA;GDNF GO:0007165| signal transduction GDNF;CD86;CCL2 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA GO:0006955| immune response CCL2;CD86 27237:[DB01281 DB01137] DB01281|Abatacept CD80;CD86 DB01137|Levofloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;ABCB1;SLC22A6;SLC22A2;SLC22A4;SLC47A1;SLC47A2 common genes common pathways 27238:[DB01281 DB05047] DB01281|Abatacept CD80;CD86 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways GO:0007165| signal transduction CD86;GRIA1;GRIA2 27239:[DB01281 DB07614] DB01281|Abatacept CD80;CD86 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways GO:0007165| signal transduction HPGDS;CD86 27240:[DB01281 DB07838] DB01281|Abatacept CD80;CD86 DB07838|(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE NMT2 common genes common pathways 27241:[DB01281 DB00876] DB01281|Abatacept CD80;CD86 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0007165| signal transduction AGTR1;CD86 27242:[DB01281 DB05316] DB01281|Abatacept CD80;CD86 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0007165| signal transduction CD86;DRD2;HTR2A GO:0008284| positive regulation of cell proliferation HTR2A;CD86 27243:[DB01281 DB05607] DB01281|Abatacept CD80;CD86 DB05607|PRX-08066 HTR2B common genes common pathways GO:0007165| signal transduction CD86;HTR2B GO:0008284| positive regulation of cell proliferation HTR2B;CD86 27244:[DB01281 DB01414] DB01281|Abatacept CD80;CD86 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways 27245:[DB01281 DB03125] DB01281|Abatacept CD80;CD86 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways 27246:[DB01281 DB08861] DB01281|Abatacept CD80;CD86 DB08861|DPDPE SLCO1B3 common genes common pathways 27247:[DB01281 DB02140] DB01281|Abatacept CD80;CD86 DB02140|N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide CTSH common genes common pathways GO:0002250| adaptive immune response CTSH;CD86 GO:0008284| positive regulation of cell proliferation CTSH;CD86 27248:[DB01281 DB04714] DB01281|Abatacept CD80;CD86 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0016032| viral reproduction CD80;FDPS;CD86 27249:[DB01281 DB06979] DB01281|Abatacept CD80;CD86 DB06979|5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid HAO1 common genes common pathways 27250:[DB01281 DB09477] DB01281|Abatacept CD80;CD86 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways GO:0007165| signal transduction CD86;BDKRB1 27251:[DB01281 DB08402] DB01281|Abatacept CD80;CD86 DB08402|2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID PPARG;NCOA2;RXRA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;RXRA;CD86;CD80 GO:0016032| viral reproduction CD80;CD86;RXRA GO:0007165| signal transduction PPARG;CD86 27252:[DB01281 DB08795] DB01281|Abatacept CD80;CD86 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 27253:[DB01281 DB07340] DB01281|Abatacept CD80;CD86 DB07340|N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine AURKB;INCENP common genes common pathways 27254:[DB01281 DB13421] DB01281|Abatacept CD80;CD86 DB13421|Edoxudine ALB common genes common pathways 27255:[DB01281 DB12023] DB01281|Abatacept CD80;CD86 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways GO:0006955| immune response FCGR3A;CD86 GO:0007165| signal transduction CD86;IL5RA 27256:[DB01281 DB13879] DB01281|Abatacept CD80;CD86 DB13879|Glecaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 27257:[DB01281 DB05423] DB01281|Abatacept CD80;CD86 DB05423|ORG-34517 NR3C1 common genes common pathways GO:0007165| signal transduction CD86;NR3C1 27258:[DB01281 DB06898] DB01281|Abatacept CD80;CD86 DB06898|4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 27259:[DB01281 DB04477] DB01281|Abatacept CD80;CD86 DB04477|N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways 27260:[DB01281 DB05415] DB01281|Abatacept CD80;CD86 DB05415|OSI-461 PDE5A common genes common pathways GO:0007165| signal transduction CD86;PDE5A 27261:[DB01281 DB04618] DB01281|Abatacept CD80;CD86 DB04618|4,6-DIDEOXY-4-{[4-[(4-O-HEXOPYRANOSYLHEXOPYRANOSYL)OXY]-5,6-DIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}HEXOPYRANOSYL-(1->4)HEXOPYRANOSYL-(1->4)HEXOPYRANOSE AMY2A common genes common pathways 27262:[DB01281 DB00431] DB01281|Abatacept CD80;CD86 DB00431|Lindane GABRB1;GLRA1;GLRA2;GLRA3;GLRB;GABRB3;GABRR1;PGR;ESR1;NR1I2 common genes common pathways GO:0007165| signal transduction GABRB3;GABRB1;ESR1;PGR;CD86;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;NR1I2;CD86 27263:[DB01281 DB06896] DB01281|Abatacept CD80;CD86 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;CD80;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;CD80;MET GO:0007165| signal transduction CD86;MET 27264:[DB01281 DB03981] DB01281|Abatacept CD80;CD86 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways GO:0007165| signal transduction CD86;ANXA5;FGF2 GO:0045893| positive regulation of transcription, DNA-dependent CD80;FGF2;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;FGF2;CD80 GO:0008284| positive regulation of cell proliferation CD86;FGF2 GO:0046854| phosphatidylinositol phosphorylation CD86;FGF2;CD80 27265:[DB01281 DB07968] DB01281|Abatacept CD80;CD86 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways 27266:[DB01281 DB03987] DB01281|Abatacept CD80;CD86 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways 27267:[DB01281 DB06512] DB01281|Abatacept CD80;CD86 DB06512|Deramciclane HTR2A;HTR2C;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation HTR2A;CD86 GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0007165| signal transduction HTR2A;CD86;HTR2C GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction CD86;CD80;HTR2A 27268:[DB01281 DB07403] DB01281|Abatacept CD80;CD86 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways 27269:[DB01281 DB05971] DB01281|Abatacept CD80;CD86 DB05971|Archexin AKT1 common genes common pathways GO:0031295| T cell costimulation CD86;CD80;AKT1 GO:0008284| positive regulation of cell proliferation AKT1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;AKT1;CD80 GO:0007165| signal transduction AKT1;CD86 GO:0035556| intracellular signal transduction CD80;AKT1 27270:[DB01281 DB02996] DB01281|Abatacept CD80;CD86 DB02996|2-(Thiomethylene)-4-Methylpentanoic Acid ADAM28 common genes common pathways 27271:[DB01281 DB06240] DB01281|Abatacept CD80;CD86 DB06240|Tariquidar ABCB1 common genes common pathways 27272:[DB01281 DB03821] DB01281|Abatacept CD80;CD86 DB03821|2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid ARSA;ARSA common genes common pathways 27273:[DB01281 DB07999] DB01281|Abatacept CD80;CD86 DB07999|{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID AKR1B1 common genes common pathways 27274:[DB01281 DB01273] DB01281|Abatacept CD80;CD86 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways GO:0007165| signal transduction CHRNA7;CHRNA4;CHRNA6;CD86;CHRNA3;CHRNB2 GO:0008284| positive regulation of cell proliferation CHRNA7;CD86 27275:[DB01281 DB08856] DB01281|Abatacept CD80;CD86 DB08856|DADLE SLCO1B1 common genes common pathways 27276:[DB01281 DB07447] DB01281|Abatacept CD80;CD86 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways 27277:[DB01281 DB08729] DB01281|Abatacept CD80;CD86 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways GO:0007165| signal transduction CD86;PDE5A 27278:[DB01281 DB09037] DB01281|Abatacept CD80;CD86 DB09037|Pembrolizumab PDCD1 common genes common pathways GO:0007165| signal transduction CD86;PDCD1 GO:0031295| T cell costimulation PDCD1;CD80;CD86 GO:0002376| immune system process PDCD1;CD86 27279:[DB01281 DB11752] DB01281|Abatacept CD80;CD86 DB11752|Bryostatin 1 CYP3A4 common genes common pathways 27280:[DB01281 DB00498] DB01281|Abatacept CD80;CD86 DB00498|Phenindione VKORC1 common genes common pathways 27281:[DB01281 DB03194] DB01281|Abatacept CD80;CD86 DB03194|beta-L-methyl-fucose MBL2 common genes common pathways GO:0002376| immune system process MBL2;CD86 27282:[DB01281 DB08878] DB01281|Abatacept CD80;CD86 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways 27283:[DB01281 DB14146] DB01281|Abatacept CD80;CD86 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0006955| immune response CD86;OPRK1;OPRD1 GO:0007165| signal transduction OPRD1;OPRM1;CD86;OPRK1 27284:[DB01281 DB14029] DB01281|Abatacept CD80;CD86 DB14029|Furafylline CYP1A2 common genes common pathways 27285:[DB01281 DB09107] DB01281|Abatacept CD80;CD86 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways GO:0007165| signal transduction EPOR;CD86 27286:[DB01281 DB03005] DB01281|Abatacept CD80;CD86 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 27287:[DB01281 DB00159] DB01281|Abatacept CD80;CD86 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0007165| signal transduction CD86;PPARG;FFAR1 GO:0008284| positive regulation of cell proliferation PTGS2;PPARD;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARD;PPARA;CD86;PPARG 27288:[DB01281 DB04903] DB01281|Abatacept CD80;CD86 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways 27289:[DB01281 DB04273] DB01281|Abatacept CD80;CD86 DB04273|8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine PNMT common genes common pathways 27290:[DB01281 DB02831] DB01281|Abatacept CD80;CD86 DB02831|Dihydrogenphosphate DCXR common genes common pathways 27291:[DB01281 DB00649] DB01281|Abatacept CD80;CD86 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes common pathways 27292:[DB01281 DB13200] DB01281|Abatacept CD80;CD86 DB13200|Lipegfilgrastim CSF3R common genes common pathways GO:0007165| signal transduction CD86;CSF3R 27293:[DB01281 DB07406] DB01281|Abatacept CD80;CD86 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways 27294:[DB01281 DB00985] DB01281|Abatacept CD80;CD86 DB00985|Dimenhydrinate HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 27295:[DB01281 DB01643] DB01281|Abatacept CD80;CD86 DB01643|Thymidine monophosphate tmk;DTYMK;dnaQ;TYMS;thyA;topA common genes common pathways 27296:[DB01281 DB00727] DB01281|Abatacept CD80;CD86 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0035556| intracellular signal transduction CD80;NPR1 27297:[DB01281 DB00785] DB01281|Abatacept CD80;CD86 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CD86;CHRM4;CHRM3;CHRM2;CHRM1;CHRM5 27298:[DB01281 DB05197] DB01281|Abatacept CD80;CD86 DB05197|Sofalcone CBR1 common genes common pathways 27299:[DB01281 DB07369] DB01281|Abatacept CD80;CD86 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;MET GO:0046854| phosphatidylinositol phosphorylation CD86;CD80;MET GO:0007165| signal transduction CD86;MET 27300:[DB01281 DB00951] DB01281|Abatacept CD80;CD86 DB00951|Isoniazid katG;CYP2C8;CYP1A2;CYP3A4;CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2D6;CYP2C19;NAT2;CYP2A6;CYP2C8;ALB common genes common pathways 27301:[DB01281 DB00988] DB01281|Abatacept CD80;CD86 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0008284| positive regulation of cell proliferation DRD3;CD86;HTR1A GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD1;DRD5;HTR3B;HTR1A;DRD4;CD86;DRD2;HTR7;HTR3A;DRD3 27302:[DB01281 DB00450] DB01281|Abatacept CD80;CD86 DB00450|Droperidol DRD2;ADRA1A common genes common pathways GO:0007165| signal transduction CD86;DRD2;ADRA1A GO:0035556| intracellular signal transduction CD80;DRD2;ADRA1A 27303:[DB01281 DB12742] DB01281|Abatacept CD80;CD86 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0035556| intracellular signal transduction KIT;CD80 GO:0016032| viral reproduction CD80;PDGFRA;CD86 GO:0007165| signal transduction CD86;RET;KIT;MET GO:0008284| positive regulation of cell proliferation PDGFRA;CD86;KIT;FLT3 GO:0051897| positive regulation of protein kinase B signaling cascade KIT;CD80;MET;PDGFRA;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;RET GO:0046854| phosphatidylinositol phosphorylation KIT;MET;CD80;CD86;PDGFRA 27304:[DB01281 DB03828] DB01281|Abatacept CD80;CD86 DB03828|RU78299 SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;SRC;CD86 GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0002376| immune system process CD86;SRC GO:0016032| viral reproduction SRC;CD80;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0035556| intracellular signal transduction CD80;SRC GO:0007165| signal transduction SRC;CD86 27305:[DB01281 DB02240] DB01281|Abatacept CD80;CD86 DB02240|Quinacrine mustard TPR common genes common pathways GO:0016032| viral reproduction CD86;TPR;CD80 27306:[DB01281 DB08240] DB01281|Abatacept CD80;CD86 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways 27307:[DB01281 DB08697] DB01281|Abatacept CD80;CD86 DB08697|4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 27308:[DB01281 DB06043] DB01281|Abatacept CD80;CD86 DB06043|Olaratumab PDGFRA common genes common pathways GO:0016032| viral reproduction PDGFRA;CD86;CD80 GO:0008284| positive regulation of cell proliferation PDGFRA;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;PDGFRA;CD86 GO:0046854| phosphatidylinositol phosphorylation PDGFRA;CD86;CD80 27309:[DB01281 DB01579] DB01281|Abatacept CD80;CD86 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0007165| signal transduction CD86;ADRA1A;ADRA1B GO:0035556| intracellular signal transduction CD80;ADRA1B;ADRA1A 27310:[DB01281 DB03848] DB01281|Abatacept CD80;CD86 DB03848|Benzenesulfinic acid NR1H2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1H2;CD86;CD80 27311:[DB01281 DB05964] DB01281|Abatacept CD80;CD86 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction CD86;DRD2 27312:[DB01281 DB05129] DB01281|Abatacept CD80;CD86 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways GO:0016032| viral reproduction CD86;CD80;TOP1 27313:[DB01281 DB07359] DB01281|Abatacept CD80;CD86 DB07359|3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide GCK common genes common pathways 27314:[DB01281 DB06663] DB01281|Abatacept CD80;CD86 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0007165| signal transduction SSTR3;SSTR5;SSTR2;SSTR1;CD86 27315:[DB01281 DB07753] DB01281|Abatacept CD80;CD86 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways 27316:[DB01281 DB00082] DB01281|Abatacept CD80;CD86 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;GHR 27317:[DB01281 DB07875] DB01281|Abatacept CD80;CD86 DB07875|5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 27318:[DB01281 DB01034] DB01281|Abatacept CD80;CD86 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways 27319:[DB01281 DB07555] DB01281|Abatacept CD80;CD86 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways 27320:[DB01281 DB07011] DB01281|Abatacept CD80;CD86 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways 27321:[DB01281 DB08773] DB01281|Abatacept CD80;CD86 DB08773|RALOXIFENE CORE ESR1;NCOA2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 GO:0007165| signal transduction CD86;ESR1 27322:[DB01281 DB03867] DB01281|Abatacept CD80;CD86 DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways 27323:[DB01281 DB03568] DB01281|Abatacept CD80;CD86 DB03568|Butyric Acid BCHE;BCHE common genes common pathways 27324:[DB01281 DB01861] DB01281|Abatacept CD80;CD86 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 27325:[DB01281 DB09137] DB01281|Abatacept CD80;CD86 DB09137|Technetium Tc-99m mebrofenin SLCO1B1;SLCO1B3 common genes common pathways 27326:[DB01281 DB03046] DB01281|Abatacept CD80;CD86 DB03046|7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 27327:[DB01281 DB09300] DB01281|Abatacept CD80;CD86 DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways GO:0007165| signal transduction CHRM2;CHRM3;CD86 27328:[DB01281 DB03884] DB01281|Abatacept CD80;CD86 DB03884|Phenylpyruvic acid HAO1;SLC16A3 common genes common pathways 27329:[DB01281 DB02082] DB01281|Abatacept CD80;CD86 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways 27330:[DB01281 DB05831] DB01281|Abatacept CD80;CD86 DB05831|ING-1 EPCAM common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;EPCAM 27331:[DB01281 DB06995] DB01281|Abatacept CD80;CD86 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;MET;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;CD80;MET GO:0007165| signal transduction MET;CD86 27332:[DB01281 DB07929] DB01281|Abatacept CD80;CD86 DB07929|N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE NR1H3;RXRB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;NR1H3 27333:[DB01281 DB07479] DB01281|Abatacept CD80;CD86 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways 27334:[DB01281 DB03784] DB01281|Abatacept CD80;CD86 DB03784|Elaidoylamide PLA2G2A common genes common pathways 27335:[DB01281 DB06199] DB01281|Abatacept CD80;CD86 DB06199|Atrasentan EDNRA common genes common pathways GO:0007165| signal transduction EDNRA;CD86 27336:[DB01281 DB08130] DB01281|Abatacept CD80;CD86 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;MAP2K1;CD86 GO:0007165| signal transduction CD86;MAP2K1 27337:[DB01281 DB00028] DB01281|Abatacept CD80;CD86 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:0002376| immune system process FCGR1B;C5;C3;C4B;C4A;FCGR2A;FCGR1A;CD86 GO:0002250| adaptive immune response CD86;FCGR1B GO:0007165| signal transduction FCGR2C;C3;FCGR1A;CD86;FCGR2B GO:0006955| immune response FCGR2C;FCGR3A;FCGR1B;C3;FCGR3B;FCGR2B;FCGR1A;CD86 GO:0016032| viral reproduction CD80;FCGR2B;CD86 27338:[DB01281 DB04622] DB01281|Abatacept CD80;CD86 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways 27339:[DB01281 DB06196] DB01281|Abatacept CD80;CD86 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways GO:0007165| signal transduction BDKRB2;ANPEP;CD86 GO:0046718| entry of virus into host cell CD86;CD80;ANPEP GO:0016032| viral reproduction ANPEP;CD80;CD86 27340:[DB01281 DB14057] DB01281|Abatacept CD80;CD86 DB14057|Valinomycin ABCB11 common genes common pathways 27341:[DB01281 DB01246] DB01281|Abatacept CD80;CD86 DB01246|Alimemazine HRH1;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;HRH1 27342:[DB01281 DB00366] DB01281|Abatacept CD80;CD86 DB00366|Doxylamine HRH1;CHRM1;NR1I3;CYP2B common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction HRH1;NR1I3;CHRM1;CD86 27343:[DB01281 DB01442] DB01281|Abatacept CD80;CD86 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0046718| entry of virus into host cell CD86;HTR2A;CD80 GO:0007165| signal transduction CD86;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation HTR2A;CD80 GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0008284| positive regulation of cell proliferation HTR2A;CD86 27344:[DB01281 DB06980] DB01281|Abatacept CD80;CD86 DB06980|(2S)-2-(1H-indol-3-yl)hexanoic acid SKP1 common genes common pathways 27345:[DB01281 DB07139] DB01281|Abatacept CD80;CD86 DB07139|3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid AKR1B1 common genes common pathways 27346:[DB01281 DB07760] DB01281|Abatacept CD80;CD86 DB07760|3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid UNG common genes common pathways GO:0016032| viral reproduction CD80;CD86;UNG 27347:[DB01281 DB06900] DB01281|Abatacept CD80;CD86 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways 27348:[DB01281 DB00899] DB01281|Abatacept CD80;CD86 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007165| signal transduction CD86;OPRK1;OPRD1;OPRM1 GO:0006955| immune response OPRD1;CD86;OPRK1 27349:[DB01281 DB00218] DB01281|Abatacept CD80;CD86 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways 27350:[DB01281 DB08842] DB01281|Abatacept CD80;CD86 DB08842|Acetylcarnitine SLC22A5 common genes common pathways 27351:[DB01281 DB03708] DB01281|Abatacept CD80;CD86 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways 27352:[DB01281 DB05199] DB01281|Abatacept CD80;CD86 DB05199|LX1031 TPH1 common genes common pathways 27353:[DB01281 DB05882] DB01281|Abatacept CD80;CD86 DB05882|CHF 4227 ESR1;ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;ESR2;CD86 GO:0007165| signal transduction ESR1;CD86;ESR2 27354:[DB01281 DB08249] DB01281|Abatacept CD80;CD86 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways 27355:[DB01281 DB13165] DB01281|Abatacept CD80;CD86 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0007165| signal transduction CD86;ROCK1 GO:0035556| intracellular signal transduction CD80;ROCK1;ROCK2 27356:[DB01281 DB04779] DB01281|Abatacept CD80;CD86 DB04779|ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 27357:[DB01281 DB03346] DB01281|Abatacept CD80;CD86 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways 27358:[DB01281 DB00686] DB01281|Abatacept CD80;CD86 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0007165| signal transduction CD86;FGF4;FGF1;FGF2 GO:0046854| phosphatidylinositol phosphorylation CD86;FGF4;FGF1;FGF2;CD80 GO:0008284| positive regulation of cell proliferation CD86;FGF4;FGF1;FGF2 GO:0051897| positive regulation of protein kinase B signaling cascade FGF2;CD80;FGF1;FGF4;CD86 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;CD80;CD86 27359:[DB01281 DB07208] DB01281|Abatacept CD80;CD86 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD80 GO:0007165| signal transduction CD86;PPARG 27360:[DB01281 DB09093] DB01281|Abatacept CD80;CD86 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways 27361:[DB01281 DB07744] DB01281|Abatacept CD80;CD86 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways GO:0007165| signal transduction CASP1;CD86 27362:[DB01281 DB05642] DB01281|Abatacept CD80;CD86 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0007165| signal transduction HTR3A;CD86 27363:[DB01281 DB08584] DB01281|Abatacept CD80;CD86 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways GO:0046854| phosphatidylinositol phosphorylation CD86;MET;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;MET;CD80 GO:0007165| signal transduction CD86;MET 27364:[DB01281 DB04859] DB01281|Abatacept CD80;CD86 DB04859|Zanapezil ACHE common genes common pathways 27365:[DB01281 DB12548] DB01281|Abatacept CD80;CD86 DB12548|Sparsentan AGT;EDNRA common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;AGT GO:0007165| signal transduction CD86;EDNRA GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AGT GO:0008284| positive regulation of cell proliferation AGT;CD86 27366:[DB01281 DB07269] DB01281|Abatacept CD80;CD86 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 27367:[DB01281 DB00792] DB01281|Abatacept CD80;CD86 DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways GO:0007165| signal transduction CD86;HRH1 27368:[DB01281 DB14070] DB01281|Abatacept CD80;CD86 DB14070|HM-30181 ABCB1 common genes common pathways 27369:[DB01281 DB05736] DB01281|Abatacept CD80;CD86 DB05736|MIV-701 CTSK common genes common pathways 27370:[DB01281 DB07115] DB01281|Abatacept CD80;CD86 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 27371:[DB01281 DB03477] DB01281|Abatacept CD80;CD86 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 27372:[DB01281 DB05295] DB01281|Abatacept CD80;CD86 DB05295|Eldecalcitol VDR common genes common pathways GO:0007165| signal transduction VDR;CD86 27373:[DB01281 DB08566] DB01281|Abatacept CD80;CD86 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 27374:[DB01281 DB11156] DB01281|Abatacept CD80;CD86 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CHRM1;CD86;GPR35 27375:[DB01281 DB03878] DB01281|Abatacept CD80;CD86 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ABL1 27376:[DB01281 DB05131] DB01281|Abatacept CD80;CD86 DB05131|TTP889 F9 common genes common pathways 27377:[DB01281 DB09257] DB01281|Abatacept CD80;CD86 DB09257|Gimeracil DPYD common genes common pathways 27378:[DB01281 DB07328] DB01281|Abatacept CD80;CD86 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 27379:[DB01281 DB08705] DB01281|Abatacept CD80;CD86 DB08705|6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE PIM1 common genes common pathways 27380:[DB01281 DB03434] DB01281|Abatacept CD80;CD86 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways 27381:[DB01281 DB00429] DB01281|Abatacept CD80;CD86 DB00429|Carboprost tromethamine PTGER1 common genes common pathways GO:0007165| signal transduction PTGER1;CD86 27382:[DB01281 DB07899] DB01281|Abatacept CD80;CD86 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways 27383:[DB01281 DB09546] DB01281|Abatacept CD80;CD86 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways 27384:[DB01281 DB08964] DB01281|Abatacept CD80;CD86 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways GO:0007165| signal transduction PTGER3;PTGER2;CD86 27385:[DB01281 DB00981] DB01281|Abatacept CD80;CD86 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0007165| signal transduction CD86;CHRNB2;CHRNA4 27386:[DB01281 DB05507] DB01281|Abatacept CD80;CD86 DB05507|VX-765 CASP1;IL1B common genes common pathways GO:0006955| immune response CD86;IL1B GO:0007165| signal transduction CASP1;IL1B;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;IL1B;CD86 GO:0008284| positive regulation of cell proliferation IL1B;CD86 GO:0045086| positive regulation of interleukin-2 biosynthetic process IL1B;CD86;CD80 27387:[DB01281 DB01133] DB01281|Abatacept CD80;CD86 DB01133|Tiludronic acid ATP6V1A;PTPN1 common genes common pathways 27388:[DB01281 DB07846] DB01281|Abatacept CD80;CD86 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways 27389:[DB01281 DB06550] DB01281|Abatacept CD80;CD86 DB06550|Bivatuzumab CD44 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD44;CD80 27390:[DB01281 DB04144] DB01281|Abatacept CD80;CD86 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways GO:0016032| viral reproduction MDM2;CD86;CD80 GO:0008284| positive regulation of cell proliferation MDM2;CD86 27391:[DB01281 DB07430] DB01281|Abatacept CD80;CD86 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways 27392:[DB01281 DB03639] DB01281|Abatacept CD80;CD86 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways GO:0008284| positive regulation of cell proliferation DHPS;CD86 27393:[DB01281 DB07563] DB01281|Abatacept CD80;CD86 DB07563|1-{7-cyclohexyl-6-[4-(4-methylpiperazin-1-yl)benzyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine CTSK common genes common pathways 27394:[DB01281 DB11133] DB01281|Abatacept CD80;CD86 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent SREBF1;CD86;PPARG;CD80;PPARA GO:0008284| positive regulation of cell proliferation PTGS2;CD86 GO:0007165| signal transduction PPARG;CD86 27395:[DB01281 DB02376] DB01281|Abatacept CD80;CD86 DB02376|D-gluconhydroximo-1,5-lactam LCT common genes common pathways 27396:[DB01281 DB01325] DB01281|Abatacept CD80;CD86 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways 27397:[DB01281 DB01353] DB01281|Abatacept CD80;CD86 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GABRA6;GRIA2;CHRNA4;CHRNA7;GABRA5;CD86 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 27398:[DB01281 DB07845] DB01281|Abatacept CD80;CD86 DB07845|2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide MAPK8 common genes common pathways 27399:[DB01281 DB04537] DB01281|Abatacept CD80;CD86 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways 27400:[DB01281 DB13934] DB01281|Abatacept CD80;CD86 DB13934|Ligandrol AR common genes common pathways GO:0007165| signal transduction CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR 27401:[DB01281 DB04985] DB01281|Abatacept CD80;CD86 DB04985|Tigapotide RPSA common genes common pathways GO:0016032| viral reproduction RPSA;CD80;CD86 GO:0046718| entry of virus into host cell RPSA;CD80;CD86 27402:[DB01281 DB01162] DB01281|Abatacept CD80;CD86 DB01162|Terazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ABCB1 common genes common pathways GO:0007165| signal transduction ADRA1A;CD86;ADRA1D;ADRA1B GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A GO:0008284| positive regulation of cell proliferation CD86;ADRA1D 27403:[DB01281 DB05141] DB01281|Abatacept CD80;CD86 DB05141|LY2181308 BIRC5 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BIRC5 27404:[DB01281 DB00058] DB01281|Abatacept CD80;CD86 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways 27405:[DB01281 DB04398] DB01281|Abatacept CD80;CD86 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways 27406:[DB01281 DB06883] DB01281|Abatacept CD80;CD86 DB06883|1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea SRC common genes common pathways GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction CD80;SRC;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0007165| signal transduction CD86;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0002376| immune system process CD86;SRC 27407:[DB01281 DB13174] DB01281|Abatacept CD80;CD86 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1H2;CD86;NR1H3;CD80 27408:[DB01281 DB05099] DB01281|Abatacept CD80;CD86 DB05099|Ancrod FGA common genes common pathways GO:0007165| signal transduction FGA;CD86 GO:0002250| adaptive immune response FGA;CD86 GO:0002376| immune system process FGA;CD86 27409:[DB01281 DB07031] DB01281|Abatacept CD80;CD86 DB07031|3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid RARG common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CD86 27410:[DB01281 DB11359] DB01281|Abatacept CD80;CD86 DB11359|Guaiacol ALB common genes common pathways 27411:[DB01281 DB07161] DB01281|Abatacept CD80;CD86 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways GO:0002250| adaptive immune response CD86;JAK2 GO:0008284| positive regulation of cell proliferation JAK2;CD86 GO:0002376| immune system process JAK2;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation JAK2;CD80 GO:0035556| intracellular signal transduction CD80;JAK2 GO:0007165| signal transduction JAK2;CD86 27412:[DB01281 DB03777] DB01281|Abatacept CD80;CD86 DB03777|Rbt205 Inhibitor PIM1;PDPK1;PRKCI common genes common pathways GO:0035556| intracellular signal transduction PDPK1;CD80;PRKCI GO:0031295| T cell costimulation CD86;PDPK1;CD80 27413:[DB01281 DB03677] DB01281|Abatacept CD80;CD86 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways 27414:[DB01281 DB11738] DB01281|Abatacept CD80;CD86 DB11738|Rilmenidine ADRA2A common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ADRA2A GO:0007165| signal transduction ADRA2A;CD86 27415:[DB01281 DB08009] DB01281|Abatacept CD80;CD86 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways GO:0035556| intracellular signal transduction CD80;CAMK1G 27416:[DB01281 DB03886] DB01281|Abatacept CD80;CD86 DB03886|Biopterin SPR;PTS;DHFR common genes common pathways 27417:[DB01281 DB02530] DB01281|Abatacept CD80;CD86 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways GO:0007165| signal transduction GABBR1;CD86;GABBR2 27418:[DB01281 DB05879] DB01281|Abatacept CD80;CD86 DB05879|AME-527 TNF common genes common pathways GO:0006955| immune response CD86;TNF GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;TNF GO:0051897| positive regulation of protein kinase B signaling cascade CD86;TNF;CD80 27419:[DB01281 DB11186] DB01281|Abatacept CD80;CD86 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes common pathways GO:0007165| signal transduction OPRM1;CD86;OPRK1 GO:0006955| immune response OPRK1;CD86 27420:[DB01281 DB13877] DB01281|Abatacept CD80;CD86 DB13877|Iniparib PARP1 common genes common pathways 27421:[DB01281 DB04476] DB01281|Abatacept CD80;CD86 DB04476|Trencam-3,2-Hopo LCN2 common genes common pathways GO:0002376| immune system process LCN2;CD86 27422:[DB01281 DB08325] DB01281|Abatacept CD80;CD86 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways 27423:[DB01281 DB07449] DB01281|Abatacept CD80;CD86 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0002376| immune system process CD86;PADI4 27424:[DB01281 DB01279] DB01281|Abatacept CD80;CD86 DB01279|Galsulfase PLIN3 common genes common pathways 27425:[DB01281 DB00391] DB01281|Abatacept CD80;CD86 DB00391|Sulpiride DRD2;DRD3;CA2;CA3;BCHE common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD3;CD86;DRD2 GO:0008284| positive regulation of cell proliferation CD86;DRD3 27426:[DB01281 DB00388] DB01281|Abatacept CD80;CD86 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA1D;CD86 GO:0007165| signal transduction CD86;ADRA1A;ADRA1D;ADRA1B GO:0035556| intracellular signal transduction ADRA1A;ADRA1B;CD80 27427:[DB01281 DB07933] DB01281|Abatacept CD80;CD86 DB07933|Erteberel ESR2;ESR1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86;ESR2 GO:0007165| signal transduction ESR1;ESR2;CD86 27428:[DB01281 DB07283] DB01281|Abatacept CD80;CD86 DB07283|9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid FABP4 common genes common pathways 27429:[DB01281 DB00819] DB01281|Abatacept CD80;CD86 DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways 27430:[DB01281 DB00284] DB01281|Abatacept CD80;CD86 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 27431:[DB01281 DB01401] DB01281|Abatacept CD80;CD86 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 27432:[DB01281 DB08739] DB01281|Abatacept CD80;CD86 DB08739|2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dione PREP common genes common pathways 27433:[DB01281 DB09085] DB01281|Abatacept CD80;CD86 DB09085|Tetracaine RYR1;RYR2 common genes common pathways 27434:[DB01281 DB06560] DB01281|Abatacept CD80;CD86 DB06560|Pascolizumab IL4 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent IL4;CD86;CD80 GO:0006955| immune response CD86;IL4 27435:[DB01281 DB05889] DB01281|Abatacept CD80;CD86 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways 27436:[DB01281 DB05367] DB01281|Abatacept CD80;CD86 DB05367|Actelion-1 EDNRA common genes common pathways GO:0007165| signal transduction EDNRA;CD86 27437:[DB01281 DB01004] DB01281|Abatacept CD80;CD86 DB01004|Ganciclovir SLC22A1;SLC22A6;SLC22A8;SLC22A7;SLC47A1;SLC47A2 common genes common pathways 27438:[DB01281 DB00719] DB01281|Abatacept CD80;CD86 DB00719|Azatadine HRH1;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;HRH1 27439:[DB01281 DB08499] DB01281|Abatacept CD80;CD86 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways GO:0035556| intracellular signal transduction CASP3;CD80 27440:[DB01281 DB01013] DB01281|Abatacept CD80;CD86 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 27441:[DB01281 DB00427] DB01281|Abatacept CD80;CD86 DB00427|Triprolidine HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 27442:[DB01281 DB12020] DB01281|Abatacept CD80;CD86 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways 27443:[DB01281 DB04971] DB01281|Abatacept CD80;CD86 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;PPARA;CD80 27444:[DB01281 DB00703] DB01281|Abatacept CD80;CD86 DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways 27445:[DB01281 DB00337] DB01281|Abatacept CD80;CD86 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation MTOR;CD80 GO:0007165| signal transduction CD86;MTOR GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;MTOR 27446:[DB01281 DB05092] DB01281|Abatacept CD80;CD86 DB05092|CDP323 ITGA4 common genes common pathways 27447:[DB01281 DB01340] DB01281|Abatacept CD80;CD86 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways 27448:[DB01281 DB05297] DB01281|Abatacept CD80;CD86 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0008284| positive regulation of cell proliferation BCL2;CD86 27449:[DB01281 DB03738] DB01281|Abatacept CD80;CD86 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 27450:[DB01281 DB00009] DB01281|Abatacept CD80;CD86 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007165| signal transduction PLAUR;FGA;CD86 GO:0002250| adaptive immune response FGA;CD86 GO:0002376| immune system process CD86;FGA 27451:[DB01281 DB08890] DB01281|Abatacept CD80;CD86 DB08890|Linaclotide GUCY2C common genes common pathways GO:0035556| intracellular signal transduction GUCY2C;CD80 27452:[DB01281 DB12364] DB01281|Abatacept CD80;CD86 DB12364|Betrixaban F10;F2;ABCB1;KCNH2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 GO:0008284| positive regulation of cell proliferation CD86;F2 27453:[DB01281 DB11134] DB01281|Abatacept CD80;CD86 DB11134|Cupric oxide ALB;CP common genes common pathways 27454:[DB01281 DB07285] DB01281|Abatacept CD80;CD86 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 27455:[DB01281 DB03390] DB01281|Abatacept CD80;CD86 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways 27456:[DB01281 DB07419] DB01281|Abatacept CD80;CD86 DB07419|S-23 AR common genes common pathways GO:0007165| signal transduction AR;CD86 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 27457:[DB01281 DB01001] DB01281|Abatacept CD80;CD86 DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways GO:0007165| signal transduction ADRB2;ADRB1;CD86;ADRB3 27458:[DB01281 DB04689] DB01281|Abatacept CD80;CD86 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARG;CD86;CD80 GO:0007165| signal transduction CD86;PPARG 27459:[DB01281 DB04577] DB01281|Abatacept CD80;CD86 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD80;DPP4;CD86 27460:[DB01281 DB04099] DB01281|Abatacept CD80;CD86 DB04099|Deamido-Nad+ nadE;NMNAT1;nadD;NMNAT3;nadE;nadE common genes common pathways 27461:[DB01281 DB07069] DB01281|Abatacept CD80;CD86 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 27462:[DB01281 DB07728] DB01281|Abatacept CD80;CD86 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0007165| signal transduction MAPKAPK3;CD86 27463:[DB01281 DB00509] DB01281|Abatacept CD80;CD86 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways 27464:[DB01281 DB11118] DB01281|Abatacept CD80;CD86 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways 27465:[DB01281 DB08766] DB01281|Abatacept CD80;CD86 DB08766|Zofenoprilat LAP3 common genes common pathways 27466:[DB01281 DB01809] DB01281|Abatacept CD80;CD86 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0016032| viral reproduction CD80;HCK;CD86 GO:0007165| signal transduction RET;CD86 GO:0008284| positive regulation of cell proliferation HCK;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;RET;CD86 GO:0002376| immune system process CD86;HCK 27467:[DB01281 DB00833] DB01281|Abatacept CD80;CD86 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways 27468:[DB01281 DB01765] DB01281|Abatacept CD80;CD86 DB01765|(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 GO:0007165| signal transduction CSNK2A1;CD86 27469:[DB01281 DB01549] DB01281|Abatacept CD80;CD86 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0007165| signal transduction CD86;DRD2 GO:0035556| intracellular signal transduction CD80;DRD2 27470:[DB01281 DB06788] DB01281|Abatacept CD80;CD86 DB06788|Histrelin GNRHR common genes common pathways GO:0007165| signal transduction GNRHR;CD86 27471:[DB01281 DB03612] DB01281|Abatacept CD80;CD86 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways 27472:[DB01281 DB08399] DB01281|Abatacept CD80;CD86 DB08399|PICEATANNOL ATP5B common genes common pathways 27473:[DB01281 DB02422] DB01281|Abatacept CD80;CD86 DB02422|Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside MAN1B1 common genes common pathways 27474:[DB01281 DB07597] DB01281|Abatacept CD80;CD86 DB07597|CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 27475:[DB01281 DB08287] DB01281|Abatacept CD80;CD86 DB08287|(1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide CTSK common genes common pathways 27476:[DB01281 DB02457] DB01281|Abatacept CD80;CD86 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways 27477:[DB01281 DB04057] DB01281|Abatacept CD80;CD86 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways 27478:[DB01281 DB08831] DB01281|Abatacept CD80;CD86 DB08831|2-deoxyglucose SLC2A1 common genes common pathways 27479:[DB01281 DB12323] DB01281|Abatacept CD80;CD86 DB12323|Radotinib ABL1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation ABL1;CD80 27480:[DB01281 DB01840] DB01281|Abatacept CD80;CD86 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways 27481:[DB01281 DB02358] DB01281|Abatacept CD80;CD86 DB02358|LY374571 MTHFD1 common genes common pathways 27482:[DB01281 DB04864] DB01281|Abatacept CD80;CD86 DB04864|Huperzine A ACHE common genes common pathways 27483:[DB01281 DB06834] DB01281|Abatacept CD80;CD86 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways GO:0035556| intracellular signal transduction SYK;CD80 GO:0016032| viral reproduction SYK;CD86;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SYK GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process CD80;SYK GO:0002250| adaptive immune response CD86;SYK GO:0002376| immune system process SYK;CD86 27484:[DB01281 DB07715] DB01281|Abatacept CD80;CD86 DB07715|Emodin CSNK2A1;fabZ;AHR common genes common pathways GO:0007165| signal transduction CSNK2A1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;AHR;CD86 GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 27485:[DB01281 DB08691] DB01281|Abatacept CD80;CD86 DB08691|ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate CLK1;CLK3 common genes common pathways 27486:[DB01281 DB00161] DB01281|Abatacept CD80;CD86 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways 27487:[DB01281 DB05152] DB01281|Abatacept CD80;CD86 DB05152|NGX267 CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;CD86 GO:0007165| signal transduction CD86;CHRM1 27488:[DB01281 DB01931] DB01281|Abatacept CD80;CD86 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways 27489:[DB01281 DB04954] DB01281|Abatacept CD80;CD86 DB04954|Tecadenoson ADORA1 common genes common pathways GO:0007165| signal transduction ADORA1;CD86 27490:[DB01281 DB02659] DB01281|Abatacept CD80;CD86 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0016032| viral reproduction CD86;SLC10A1;CD80 GO:0035556| intracellular signal transduction CD80;PLA2G1B GO:0046718| entry of virus into host cell CD86;SLC10A1;CD80 GO:0007165| signal transduction GPBAR1;PLA2G1B;CD86;NR1H4 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESRRG;CD86 GO:0002376| immune system process NR1H4;CD86 27491:[DB01281 DB01189] DB01281|Abatacept CD80;CD86 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes common pathways GO:0007165| signal transduction CD86;GRIA1;GABRD;GABRP;GABRA5;GABRB3;ATP2C1;GABRA6;GABRE;GABRB1;GABRQ 27492:[DB01281 DB05110] DB01281|Abatacept CD80;CD86 DB05110|VIR201 IFNG common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;IFNG GO:0002250| adaptive immune response CD86;IFNG GO:0006955| immune response IFNG;CD86 27493:[DB01281 DB04307] DB01281|Abatacept CD80;CD86 DB04307|5-Hydroxy-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways 27494:[DB01281 DB04899] DB01281|Abatacept CD80;CD86 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways GO:0035556| intracellular signal transduction NPR2;NPR1;CD80 27495:[DB01281 DB05829] DB01281|Abatacept CD80;CD86 DB05829|Parathyroid hormone PTH1R;PTH2R common genes common pathways GO:0007165| signal transduction CD86;PTH2R;PTH1R GO:0008284| positive regulation of cell proliferation PTH1R;CD86 27496:[DB01281 DB06194] DB01281|Abatacept CD80;CD86 DB06194|Elocalcitol VDR common genes common pathways GO:0007165| signal transduction CD86;VDR 27497:[DB01281 DB12116] DB01281|Abatacept CD80;CD86 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent AHR;CD86;CD80 27498:[DB01281 DB02104] DB01281|Abatacept CD80;CD86 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways 27499:[DB01281 DB05846] DB01281|Abatacept CD80;CD86 DB05846|Mito-4509 APP common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;APP 27500:[DB01281 DB08802] DB01281|Abatacept CD80;CD86 DB08802|Isothipendyl HRH1 common genes common pathways GO:0007165| signal transduction CD86;HRH1 27501:[DB01281 DB02035] DB01281|Abatacept CD80;CD86 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways 27502:[DB01281 DB04891] DB01281|Abatacept CD80;CD86 DB04891|Becocalcidiol MED1;VDR common genes common pathways GO:0007165| signal transduction VDR;CD86 GO:0008284| positive regulation of cell proliferation CD86;MED1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;MED1;CD80 27503:[DB01281 DB00610] DB01281|Abatacept CD80;CD86 DB00610|Metaraminol ADRA1A common genes common pathways GO:0007165| signal transduction ADRA1A;CD86 GO:0035556| intracellular signal transduction CD80;ADRA1A 27504:[DB01281 DB02597] DB01281|Abatacept CD80;CD86 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways 27505:[DB01281 DB02309] DB01281|Abatacept CD80;CD86 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 27506:[DB01281 DB13978] DB01281|Abatacept CD80;CD86 DB13978|Selisistat SIRT1 common genes common pathways GO:0008284| positive regulation of cell proliferation SIRT1;CD86 GO:0016032| viral reproduction SIRT1;CD86;CD80 27507:[DB01281 DB02547] DB01281|Abatacept CD80;CD86 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 27508:[DB01281 DB06429] DB01281|Abatacept CD80;CD86 DB06429|Talnetant TACR3 common genes common pathways GO:0007165| signal transduction TACR3;CD86 27509:[DB01281 DB04932] DB01281|Abatacept CD80;CD86 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0007165| signal transduction ADORA2A;ADORA1;ADORA2B;CD86 27510:[DB01281 DB00644] DB01281|Abatacept CD80;CD86 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways GO:0007165| signal transduction GNRHR;CD86;GNRHR2 27511:[DB01281 DB04927] DB01281|Abatacept CD80;CD86 DB04927|NM100060 SQLE common genes common pathways 27512:[DB01281 DB02834] DB01281|Abatacept CD80;CD86 DB02834|IDD552 AKR1B1 common genes common pathways 27513:[DB01281 DB14543] DB01281|Abatacept CD80;CD86 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0002250| adaptive immune response ANXA1;CD86 GO:0002376| immune system process ANXA1;CD86 GO:0006955| immune response CYP11B1;CD86 GO:0045627| positive regulation of T-helper 1 cell differentiation ANXA1;CD80 GO:0007165| signal transduction ANXA1;CD86;NR3C1 27514:[DB01281 DB07641] DB01281|Abatacept CD80;CD86 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways 27515:[DB01281 DB04235] DB01281|Abatacept CD80;CD86 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways 27516:[DB01281 DB00389] DB01281|Abatacept CD80;CD86 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways 27517:[DB01281 DB01164] DB01281|Abatacept CD80;CD86 DB01164|Calcium Chloride S100A13 common genes common pathways GO:0008284| positive regulation of cell proliferation S100A13;CD86 27518:[DB01281 DB08703] DB01281|Abatacept CD80;CD86 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways 27519:[DB01281 DB09283] DB01281|Abatacept CD80;CD86 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0007165| signal transduction PDE1A;PDE8B;PDE10A;PDE6A;PDE1B;PDE3B;PDE4D;PDE4A;CD86;PDE7A;PDE11A;PDE6C;PDE7B;PDE4B;PDE9A;PDE4C;PDE1C;PDE6B;PDE2A;PDE3A;PDE5A;PDE8A 27520:[DB01281 DB06941] DB01281|Abatacept CD80;CD86 DB06941|(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide S100B common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;S100B 27521:[DB01281 DB07268] DB01281|Abatacept CD80;CD86 DB07268|2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE MAPK8 common genes common pathways 27522:[DB01281 DB11772] DB01281|Abatacept CD80;CD86 DB11772|Pilaralisib PIK3CA common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;PIK3CA;CD80 GO:0002250| adaptive immune response PIK3CA;CD86 GO:0031295| T cell costimulation CD80;PIK3CA;CD86 GO:0046854| phosphatidylinositol phosphorylation PIK3CA;CD80;CD86 27523:[DB01281 DB14067] DB01281|Abatacept CD80;CD86 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways 27524:[DB01281 DB02095] DB01281|Abatacept CD80;CD86 DB02095|Isatin MAOB;MAOB common genes common pathways 27525:[DB01281 DB09568] DB01281|Abatacept CD80;CD86 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes common pathways 27526:[DB01281 DB11994] DB01281|Abatacept CD80;CD86 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1H3;CD86;NR1H2;CD80 27527:[DB01281 DB05903] DB01281|Abatacept CD80;CD86 DB05903|KOS-1584 CYP3A4 common genes common pathways 27528:[DB01281 DB00491] DB01281|Abatacept CD80;CD86 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 27529:[DB01281 DB04556] DB01281|Abatacept CD80;CD86 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways 27530:[DB01281 DB09008] DB01281|Abatacept CD80;CD86 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways 27531:[DB01281 DB06436] DB01281|Abatacept CD80;CD86 DB06436|Semaxanib KDR;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;CD86;PTGS2 GO:0016032| viral reproduction CD80;KDR;CD86 27532:[DB01281 DB04970] DB01281|Abatacept CD80;CD86 DB04970|Lesopitron HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;CD86 GO:0007165| signal transduction HTR1A;CD86 27533:[DB01281 DB06867] DB01281|Abatacept CD80;CD86 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways 27534:[DB01281 DB07412] DB01281|Abatacept CD80;CD86 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0031295| T cell costimulation CD86;DPP4;CD80 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 27535:[DB01281 DB02710] DB01281|Abatacept CD80;CD86 DB02710|2,3,-Dihydroxybenzoylserine LCN2 common genes common pathways GO:0002376| immune system process LCN2;CD86 27536:[DB01281 DB01681] DB01281|Abatacept CD80;CD86 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways 27537:[DB01281 DB08492] DB01281|Abatacept CD80;CD86 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways 27538:[DB01281 DB02504] DB01281|Abatacept CD80;CD86 DB02504|[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid PLA2G2A common genes common pathways 27539:[DB01281 DB07076] DB01281|Abatacept CD80;CD86 DB07076|6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 27540:[DB01281 DB00015] DB01281|Abatacept CD80;CD86 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007165| signal transduction PLAUR;FGA;CD86 GO:0002376| immune system process FGA;CD86 GO:0002250| adaptive immune response CD86;FGA 27541:[DB01281 DB08651] DB01281|Abatacept CD80;CD86 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways 27542:[DB01281 DB07271] DB01281|Abatacept CD80;CD86 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD86;DPP4;CD80 GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation CD86;DPP4 27543:[DB01281 DB00752] DB01281|Abatacept CD80;CD86 DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways 27544:[DB01281 DB06856] DB01281|Abatacept CD80;CD86 DB06856|6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 27545:[DB01281 DB04612] DB01281|Abatacept CD80;CD86 DB04612|N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE XIAP common genes common pathways 27546:[DB01281 DB03181] DB01281|Abatacept CD80;CD86 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways 27547:[DB01281 DB09302] DB01281|Abatacept CD80;CD86 DB09302|Alirocumab PCSK9 common genes common pathways 27548:[DB01281 DB03906] DB01281|Abatacept CD80;CD86 DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0035556| intracellular signal transduction CD80;HMOX1 27549:[DB01281 DB13044] DB01281|Abatacept CD80;CD86 DB13044|Gossypol BCL2L1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;BCL2L1 27550:[DB01281 DB12789] DB01281|Abatacept CD80;CD86 DB12789|Dinoprost PTGDR2 common genes common pathways GO:0007165| signal transduction CD86;PTGDR2 GO:0006955| immune response CD86;PTGDR2 27551:[DB01281 DB01852] DB01281|Abatacept CD80;CD86 DB01852|Kaempherol UGT3A1 common genes common pathways 27552:[DB01281 DB02235] DB01281|Abatacept CD80;CD86 DB02235|L-methionine (R)-S-oxide APP common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;APP;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP 27553:[DB01281 DB05147] DB01281|Abatacept CD80;CD86 DB05147|CYT997 TUBA1A;TUBA1B;TUBA1C;TUBA4A;TUBA3C;TUBA3E;TUBA4B;TUBB1;TUBB2A;TUBB2B;TUBB4B;TUBB3;TUBB4A;TUBB;TUBB6 common genes common pathways 27554:[DB01281 DB03551] DB01281|Abatacept CD80;CD86 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways GO:0006955| immune response CD86;PNP 27555:[DB01281 DB04043] DB01281|Abatacept CD80;CD86 DB04043|Carboxymycobactin T LCN2 common genes common pathways GO:0002376| immune system process LCN2;CD86 27556:[DB01281 DB13940] DB01281|Abatacept CD80;CD86 DB13940|2,5-Dimethoxy-4-ethylthioamphetamine HTR2A;HTR2C common genes common pathways GO:0007165| signal transduction HTR2A;CD86;HTR2C GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction HTR2A;CD80;CD86 GO:0008284| positive regulation of cell proliferation CD86;HTR2A 27557:[DB01281 DB05073] DB01281|Abatacept CD80;CD86 DB05073|SRT501 SIRT1 common genes common pathways GO:0016032| viral reproduction CD86;SIRT1;CD80 GO:0008284| positive regulation of cell proliferation SIRT1;CD86 27558:[DB01281 DB07950] DB01281|Abatacept CD80;CD86 DB07950|Indoleacetic acid PLA2G2E;SKP1;CCBL1 common genes common pathways 27559:[DB01281 DB05010] DB01281|Abatacept CD80;CD86 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways GO:0007165| signal transduction CD86;GABBR2;GABBR1 27560:[DB01281 DB00089] DB01281|Abatacept CD80;CD86 DB00089|Capromab pendetide FOLH1 common genes common pathways 27561:[DB01281 DB04583] DB01281|Abatacept CD80;CD86 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways 27562:[DB01281 DB04851] DB01281|Abatacept CD80;CD86 DB04851|Biricodar dicitrate ABCB5;ABCC1;ABCG2 common genes common pathways 27563:[DB01281 DB01675] DB01281|Abatacept CD80;CD86 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways 27564:[DB01281 DB09326] DB01281|Abatacept CD80;CD86 DB09326|Ammonia N-13 NAGS;RHCG common genes common pathways 27565:[DB01281 DB00894] DB01281|Abatacept CD80;CD86 DB00894|Testolactone CYP19A1 common genes common pathways 27566:[DB01281 DB07457] DB01281|Abatacept CD80;CD86 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways GO:0035556| intracellular signal transduction CD80;PDPK1 GO:0031295| T cell costimulation PDPK1;CD86;CD80 27567:[DB01281 DB07970] DB01281|Abatacept CD80;CD86 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways 27568:[DB01281 DB07844] DB01281|Abatacept CD80;CD86 DB07844|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 27569:[DB01281 DB07051] DB01281|Abatacept CD80;CD86 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways GO:0007165| signal transduction CD86;PDE4D 27570:[DB01281 DB08207] DB01281|Abatacept CD80;CD86 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways 27571:[DB01281 DB02924] DB01281|Abatacept CD80;CD86 DB02924|(4R)-limonene 1α,2α-epoxide LCN9 common genes common pathways 27572:[DB01281 DB00086] DB01281|Abatacept CD80;CD86 DB00086|Streptokinase PLG;F2R;PLA2G4A common genes common pathways GO:0007165| signal transduction CD86;F2R GO:0045893| positive regulation of transcription, DNA-dependent CD80;F2R;CD86 GO:0008284| positive regulation of cell proliferation F2R;CD86 27573:[DB01281 DB13995] DB01281|Abatacept CD80;CD86 DB13995|Ferric pyrophosphate citrate FTL;FTH1;HBA1;HBB common genes common pathways GO:0006955| immune response FTH1;CD86 27574:[DB01281 DB06795] DB01281|Abatacept CD80;CD86 DB06795|Mafenide CA6 common genes common pathways 27575:[DB01281 DB00447] DB01281|Abatacept CD80;CD86 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways 27576:[DB01281 DB05854] DB01281|Abatacept CD80;CD86 DB05854|CLX-0921 PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARG;CD86 GO:0007165| signal transduction PPARG;CD86 27577:[DB01281 DB00492] DB01281|Abatacept CD80;CD86 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways 27578:[DB01281 DB00986] DB01281|Abatacept CD80;CD86 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CHRM1;CHRM2;CD86;CHRM3 27579:[DB01281 DB05443] DB01281|Abatacept CD80;CD86 DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0007165| signal transduction OPRK1;CD86 GO:0006955| immune response OPRK1;CD86 27580:[DB01281 DB05098] DB01281|Abatacept CD80;CD86 DB05098|Leptin LEPR common genes common pathways 27581:[DB01281 DB00217] DB01281|Abatacept CD80;CD86 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007165| signal transduction ADRB1;ADRA2A;ADRB3;CD86;ADRA2C;ADRA2B;ADRB2 GO:0008284| positive regulation of cell proliferation CD86;ADRA2A 27582:[DB01281 DB09344] DB01281|Abatacept CD80;CD86 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways 27583:[DB01281 DB12202] DB01281|Abatacept CD80;CD86 DB12202|Zalutumumab EGFR common genes common pathways GO:0035556| intracellular signal transduction CD80;EGFR GO:0007165| signal transduction EGFR;CD86 GO:0046718| entry of virus into host cell CD80;CD86;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;EGFR GO:0045893| positive regulation of transcription, DNA-dependent CD86;EGFR;CD80 GO:0008284| positive regulation of cell proliferation CD86;EGFR GO:0046854| phosphatidylinositol phosphorylation EGFR;CD86;CD80 27584:[DB01281 DB00709] DB01281|Abatacept CD80;CD86 DB00709|Lamivudine pol;DCK;CMPK1;PGK1;NME1;NME2;PCYT1A;PCYT2;NT5C;ALB;ABCC1;SLC22A6;ABCG2;SLC22A1;SLC22A2;SLC22A3;ABCB1;ABCC4;ABCC3;ABCC2 common genes common pathways 27585:[DB01281 DB01090] DB01281|Abatacept CD80;CD86 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways GO:0007165| signal transduction CHRNB4;CD86;CHRNA3;CHRNA10 27586:[DB01281 DB12140] DB01281|Abatacept CD80;CD86 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0008284| positive regulation of cell proliferation IL6;IL1B;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;TNF GO:0045893| positive regulation of transcription, DNA-dependent TNF;IL1B;CD86;IL6;CD80 GO:0045086| positive regulation of interleukin-2 biosynthetic process IL1B;CD86;CD80 GO:0006955| immune response TNF;IL1B;CD86;IL6 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;IL6 GO:0007165| signal transduction CD86;IL1B 27587:[DB01281 DB08520] DB01281|Abatacept CD80;CD86 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways 27588:[DB01281 DB01291] DB01281|Abatacept CD80;CD86 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways GO:0007165| signal transduction ADRB1;CD86;ADRB2 27589:[DB01281 DB02054] DB01281|Abatacept CD80;CD86 DB02054|Gabaculine OAT common genes common pathways 27590:[DB01281 DB01646] DB01281|Abatacept CD80;CD86 DB01646|N-Acetylmethionine RHO common genes common pathways GO:0007165| signal transduction RHO;CD86 27591:[DB01281 DB00183] DB01281|Abatacept CD80;CD86 DB00183|Pentagastrin CCKBR;BCHE common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CCKBR GO:0007165| signal transduction CCKBR;CD86 27592:[DB01281 DB01088] DB01281|Abatacept CD80;CD86 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0006955| immune response CD86;PTGDR2 GO:0007165| signal transduction CD86;PDE4C;PDE4B;PTGIR;PTGDR2;PDE4D;PDE4A;PTGER1 27593:[DB01281 DB02884] DB01281|Abatacept CD80;CD86 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways 27594:[DB01281 DB08575] DB01281|Abatacept CD80;CD86 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways 27595:[DB01281 DB02852] DB01281|Abatacept CD80;CD86 DB02852|Domoic Acid GRIK2 common genes common pathways 27596:[DB01281 DB06413] DB01281|Abatacept CD80;CD86 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways 27597:[DB01281 DB08085] DB01281|Abatacept CD80;CD86 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways 27598:[DB01281 DB07802] DB01281|Abatacept CD80;CD86 DB07802|3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 GO:0007165| signal transduction CSNK2A1;CD86 27599:[DB01281 DB08356] DB01281|Abatacept CD80;CD86 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways 27600:[DB01281 DB09149] DB01281|Abatacept CD80;CD86 DB09149|Florbetapir (18F) APP common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP GO:0051897| positive regulation of protein kinase B signaling cascade CD86;APP;CD80 27601:[DB01281 DB00542] DB01281|Abatacept CD80;CD86 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways 27602:[DB01281 DB00742] DB01281|Abatacept CD80;CD86 DB00742|Mannitol ABCB1 common genes common pathways 27603:[DB01281 DB12391] DB01281|Abatacept CD80;CD86 DB12391|Sagopilone CYP3A4 common genes common pathways 27604:[DB01281 DB13261] DB01281|Abatacept CD80;CD86 DB13261|Sitafloxacin CYP1A2 common genes common pathways 27605:[DB01281 DB01790] DB01281|Abatacept CD80;CD86 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways GO:0035556| intracellular signal transduction CD80;PRKAR1A 27606:[DB01281 DB08565] DB01281|Abatacept CD80;CD86 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 27607:[DB01281 DB03471] DB01281|Abatacept CD80;CD86 DB03471|6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid PLA2G2A common genes common pathways 27608:[DB01281 DB07749] DB01281|Abatacept CD80;CD86 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways 27609:[DB01281 DB01093] DB01281|Abatacept CD80;CD86 DB01093|Dimethyl sulfoxide CYP2C19;CYP2D6;CYP3A4;TTR common genes common pathways 27610:[DB01281 DB09120] DB01281|Abatacept CD80;CD86 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes common pathways 27611:[DB01281 DB06116] DB01281|Abatacept CD80;CD86 DB06116|Eldelumab CXCL10 common genes common pathways GO:0006955| immune response CD86;CXCL10 GO:0007165| signal transduction CD86;CXCL10 GO:0008284| positive regulation of cell proliferation CXCL10;CD86 27612:[DB01281 DB05848] DB01281|Abatacept CD80;CD86 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways 27613:[DB01281 DB04036] DB01281|Abatacept CD80;CD86 DB04036|Coenzyme a Persulfide IVD common genes common pathways 27614:[DB01281 DB07240] DB01281|Abatacept CD80;CD86 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways 27615:[DB01281 DB00143] DB01281|Abatacept CD80;CD86 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0007165| signal transduction HPGDS;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;GPX1 27616:[DB01281 DB03466] DB01281|Abatacept CD80;CD86 DB03466|BMS184394 RARG common genes common pathways GO:0008284| positive regulation of cell proliferation RARG;CD86 27617:[DB01281 DB04834] DB01281|Abatacept CD80;CD86 DB04834|Rapacuronium CHRM2 common genes common pathways GO:0007165| signal transduction CD86;CHRM2 27618:[DB01281 DB03176] DB01281|Abatacept CD80;CD86 DB03176|KB-141 THRB;THRA common genes common pathways 27619:[DB01281 DB01785] DB01281|Abatacept CD80;CD86 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0016032| viral reproduction CD80;FDPS;CD86 27620:[DB01281 DB14039] DB01281|Abatacept CD80;CD86 DB14039|Erenumab CALCRL common genes common pathways GO:0007165| signal transduction CD86;CALCRL GO:0008284| positive regulation of cell proliferation CD86;CALCRL 27621:[DB01281 DB03683] DB01281|Abatacept CD80;CD86 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 27622:[DB01281 DB03393] DB01281|Abatacept CD80;CD86 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways GO:0016032| viral reproduction CD80;PPIA;CD86 27623:[DB01281 DB01025] DB01281|Abatacept CD80;CD86 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways GO:0002376| immune system process CD86;S100A12 GO:0046854| phosphatidylinositol phosphorylation FGF1;CD80;CD86 GO:0008284| positive regulation of cell proliferation CD86;IL3;S100A13;FGF1 GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;CD80;CD86 GO:0007165| signal transduction CD86;FGF1 GO:0006955| immune response IL3;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL3;CD80 27624:[DB01281 DB03744] DB01281|Abatacept CD80;CD86 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways 27625:[DB01281 DB01613] DB01281|Abatacept CD80;CD86 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways GO:0035556| intracellular signal transduction NPR2;CD80;NPR1 27626:[DB01281 DB01413] DB01281|Abatacept CD80;CD86 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 27627:[DB01281 DB02016] DB01281|Abatacept CD80;CD86 DB02016|R048-8071 LSS common genes common pathways 27628:[DB01281 DB02211] DB01281|Abatacept CD80;CD86 DB02211|N-Methyl-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways 27629:[DB01281 DB01878] DB01281|Abatacept CD80;CD86 DB01878|Benzophenone ESR1;ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86;ESR2 GO:0007165| signal transduction ESR2;CD86;ESR1 27630:[DB01281 DB03070] DB01281|Abatacept CD80;CD86 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways 27631:[DB01281 DB09212] DB01281|Abatacept CD80;CD86 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 27632:[DB01281 DB06089] DB01281|Abatacept CD80;CD86 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways 27633:[DB01281 DB00012] DB01281|Abatacept CD80;CD86 DB00012|Darbepoetin alfa EPOR common genes common pathways GO:0007165| signal transduction EPOR;CD86 27634:[DB01281 DB09119] DB01281|Abatacept CD80;CD86 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0007165| signal transduction CD86;P2RX4 27635:[DB01281 DB03929] DB01281|Abatacept CD80;CD86 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0046718| entry of virus into host cell SERPINB3;CD86;CD80 GO:0008284| positive regulation of cell proliferation SERPINB3;CD86 27636:[DB01281 DB08100] DB01281|Abatacept CD80;CD86 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways 27637:[DB01281 DB04523] DB01281|Abatacept CD80;CD86 DB04523|Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate CTSK common genes common pathways 27638:[DB01281 DB04673] DB01281|Abatacept CD80;CD86 DB04673|4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;F10;CD80 27639:[DB01281 DB01685] DB01281|Abatacept CD80;CD86 DB01685|Topiroxostat XDH;CYP2C8;CYP2C9;CYP1A1;CYP3A4;CYP2C19;UGT1A9;ALB;ORM1;ABCG2;SLC22A8;SLC22A6 common genes common pathways 27640:[DB01281 DB04924] DB01281|Abatacept CD80;CD86 DB04924|Itopride DRD2;ACHE common genes common pathways GO:0035556| intracellular signal transduction CD80;DRD2 GO:0007165| signal transduction CD86;DRD2 27641:[DB01281 DB12455] DB01281|Abatacept CD80;CD86 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways 27642:[DB01281 DB00774] DB01281|Abatacept CD80;CD86 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways 27643:[DB01281 DB04322] DB01281|Abatacept CD80;CD86 DB04322|LY249543 MTHFD1 common genes common pathways 27644:[DB01281 DB04575] DB01281|Abatacept CD80;CD86 DB04575|Quinestrol ESR1 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CD86 27645:[DB01281 DB06350] DB01281|Abatacept CD80;CD86 DB06350|Elinogrel P2RY12 common genes common pathways GO:0007165| signal transduction CD86;P2RY12 27646:[DB01281 DB08039] DB01281|Abatacept CD80;CD86 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways 27647:[DB01281 DB13985] DB01281|Abatacept CD80;CD86 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways GO:0007165| signal transduction CD86;SSTR4;SSTR1;SSTR2;SSTR5;SSTR3 27648:[DB01281 DB04615] DB01281|Abatacept CD80;CD86 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways 27649:[DB01281 DB01567] DB01281|Abatacept CD80;CD86 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0007165| signal transduction GABRE;GABRB1;GABRB3;GABRD;GABRP;GABRR2;GABRA5;CD86 27650:[DB01281 DB08323] DB01281|Abatacept CD80;CD86 DB08323|3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE IGHG2 common genes common pathways GO:0002250| adaptive immune response IGHG2;CD86 GO:0002376| immune system process CD86;IGHG2 27651:[DB01281 DB04376] DB01281|Abatacept CD80;CD86 DB04376|13-Acetylphorbol PRKCD common genes common pathways GO:0007165| signal transduction PRKCD;CD86 GO:0035556| intracellular signal transduction CD80;PRKCD 27652:[DB01281 DB00771] DB01281|Abatacept CD80;CD86 DB00771|Clidinium CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CD86;CHRM1 27653:[DB01281 DB05468] DB01281|Abatacept CD80;CD86 DB05468|R411 ITGA4 common genes common pathways 27654:[DB01281 DB07021] DB01281|Abatacept CD80;CD86 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways GO:0046718| entry of virus into host cell DPP4;CD86;CD80 GO:0031295| T cell costimulation CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation DPP4;CD86 27655:[DB01281 DB07226] DB01281|Abatacept CD80;CD86 DB07226|N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE WEE1 common genes common pathways 27656:[DB01281 DB06367] DB01281|Abatacept CD80;CD86 DB06367|Relacatib CTSK common genes common pathways 27657:[DB01281 DB07202] DB01281|Abatacept CD80;CD86 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways GO:0007165| signal transduction CSF1R;CD86 GO:0002376| immune system process CD86;CSF1R GO:0008284| positive regulation of cell proliferation CSF1R;CD86 27658:[DB01281 DB08791] DB01281|Abatacept CD80;CD86 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways GO:0046854| phosphatidylinositol phosphorylation MET;CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;MET GO:0007165| signal transduction MET;CD86 27659:[DB01281 DB08398] DB01281|Abatacept CD80;CD86 DB08398|2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine ESR1;NCOA2 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1 27660:[DB01281 DB00107] DB01281|Abatacept CD80;CD86 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0007165| signal transduction CD86;OXT;OXTR 27661:[DB01281 DB09214] DB01281|Abatacept CD80;CD86 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 27662:[DB01281 DB08292] DB01281|Abatacept CD80;CD86 DB08292|(5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways 27663:[DB01281 DB00659] DB01281|Abatacept CD80;CD86 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0007165| signal transduction GABRB3;GABRE;GABRQ;GABRB1;GRM5;GABRA6;CD86;GABRA5;GABRD;GABRP 27664:[DB01281 DB01609] DB01281|Abatacept CD80;CD86 DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways 27665:[DB01281 DB05540] DB01281|Abatacept CD80;CD86 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways GO:0002376| immune system process CD86;ADSSL1;ADSS 27666:[DB01281 DB03331] DB01281|Abatacept CD80;CD86 DB03331|N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways 27667:[DB01281 DB09043] DB01281|Abatacept CD80;CD86 DB09043|Albiglutide GLP1R common genes common pathways GO:0007165| signal transduction GLP1R;CD86 27668:[DB01281 DB00239] DB01281|Abatacept CD80;CD86 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes common pathways GO:0007165| signal transduction CD86;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent CD80;NR1I2;CD86 27669:[DB01281 DB00666] DB01281|Abatacept CD80;CD86 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways GO:0007165| signal transduction GNRHR;CD86;GNRHR2 27670:[DB01281 DB07697] DB01281|Abatacept CD80;CD86 DB07697|1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine PKM common genes common pathways 27671:[DB01281 DB03959] DB01281|Abatacept CD80;CD86 DB03959|N,O6-Disulfo-Glucosamine FGF2;FGF1;HS3ST3A1;HGF;ANXA5 common genes common pathways GO:0008284| positive regulation of cell proliferation FGF1;FGF2;CD86;HGF GO:0051897| positive regulation of protein kinase B signaling cascade CD86;HGF;FGF2;CD80;FGF1 GO:0045893| positive regulation of transcription, DNA-dependent CD80;FGF2;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;HGF;FGF2;CD80;FGF1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HGF GO:0007165| signal transduction FGF2;FGF1;ANXA5;CD86 27672:[DB01281 DB01608] DB01281|Abatacept CD80;CD86 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0035556| intracellular signal transduction CD80;ADRA1B GO:0007165| signal transduction CD86;ADRA2A;DRD1;ADRA1B;AR GO:0008284| positive regulation of cell proliferation AR;CD86;ADRA2A GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR 27673:[DB01281 DB06982] DB01281|Abatacept CD80;CD86 DB06982|(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid SKP1 common genes common pathways 27674:[DB01281 DB04224] DB01281|Abatacept CD80;CD86 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent PPARD;CD80;PPARA;RXRA;PPARG;CD86 GO:0008284| positive regulation of cell proliferation PPARD;CD86 GO:0016032| viral reproduction CD80;RXRA;CD86 GO:0007165| signal transduction CD86;PPARG 27675:[DB01281 DB06719] DB01281|Abatacept CD80;CD86 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0007165| signal transduction LHCGR;CD86;GNRHR 27676:[DB01281 DB14487] DB01281|Abatacept CD80;CD86 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0002376| immune system process IGKV1-17;CD86;CFB;CFH;FCN3;FGA;IGHM;CLU;C1R;C1QB;C8B;PGLYRP2;C4BPA;C8G;C4B;C1S;C5;IGHA1;C3;CFI;C1QC;S100A8;IGLV3-21;C4BPB;C8A;S100A9 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;INS;APP;CD86 GO:0002250| adaptive immune response IGHA1;IGLV3-21;IGKV1-17;CD86;JCHAIN;FGA;IGHM GO:0045893| positive regulation of transcription, DNA-dependent HDAC1;HDAC4;TP53;CD86;TP73;ESR1;CD80;MT3;AGT GO:0008284| positive regulation of cell proliferation INS;AGT;IL3;KRT6A;CD86;F2;HDAC1;HDAC4;FN1;MDM2 GO:0007165| signal transduction FGA;IGFALS;CD86;BDKRB1;PDIA3;JUP;ESR1;C3 GO:0046718| entry of virus into host cell CD86;IDE;SIVA1;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation AGT;IL3;INS;VTN;CD80;APP;TP53 GO:0006955| immune response IL3;IGLV3-21;VTN;C8A;IGHA1;C3;C1QC;IGKV1-17;CD86;JCHAIN;C1R;C8B GO:0016032| viral reproduction TP73;CFH;CD86;APOA2;TP53;MDM2;IDE;HDAC1;SIVA1;CD80 27677:[DB01281 DB01119] DB01281|Abatacept CD80;CD86 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways 27678:[DB01281 DB05490] DB01281|Abatacept CD80;CD86 DB05490|T131 PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARG;CD86 GO:0007165| signal transduction CD86;PPARG 27679:[DB01281 DB04552] DB01281|Abatacept CD80;CD86 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 GO:0035556| intracellular signal transduction PLA2G1B;CD80 GO:0007165| signal transduction PLA2G1B;CD86 27680:[DB01281 DB11217] DB01281|Abatacept CD80;CD86 DB11217|Arbutin TYR;ALB common genes common pathways 27681:[DB01281 DB03541] DB01281|Abatacept CD80;CD86 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways 27682:[DB01281 DB00138] DB01281|Abatacept CD80;CD86 DB00138|Cystine SLC7A11;CTNS;SLC7A9;SLC3A1;SLC16A10 common genes common pathways 27683:[DB01281 DB05992] DB01281|Abatacept CD80;CD86 DB05992|Plinabulin TNF common genes common pathways GO:0006955| immune response TNF;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;TNF;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;TNF 27684:[DB01281 DB01010] DB01281|Abatacept CD80;CD86 DB01010|Edrophonium ACHE;BCHE common genes common pathways 27685:[DB01281 DB01063] DB01281|Abatacept CD80;CD86 DB01063|Acetophenazine DRD2;DRD1;AR common genes common pathways GO:0007165| signal transduction DRD1;AR;DRD2;CD86 GO:0035556| intracellular signal transduction CD80;DRD2 GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR 27686:[DB01281 DB04310] DB01281|Abatacept CD80;CD86 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation PDF;CD86 27687:[DB01281 DB08479] DB01281|Abatacept CD80;CD86 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways 27688:[DB01281 DB01695] DB01281|Abatacept CD80;CD86 DB01695|N-Hydroxy-4-Phosphono-Butanamide TPI1 common genes common pathways 27689:[DB01281 DB01525] DB01281|Abatacept CD80;CD86 DB01525|Ecgonine BCHE common genes common pathways 27690:[DB01281 DB11591] DB01281|Abatacept CD80;CD86 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 27691:[DB01281 DB05352] DB01281|Abatacept CD80;CD86 DB05352|Fx-1006A TTR common genes common pathways 27692:[DB01281 DB06775] DB01281|Abatacept CD80;CD86 DB06775|Carglumic acid CPS1 common genes common pathways 27693:[DB01281 DB05969] DB01281|Abatacept CD80;CD86 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0008284| positive regulation of cell proliferation VEGFA;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CDK7;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;VEGFA 27694:[DB01281 DB00809] DB01281|Abatacept CD80;CD86 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM3;CD86;CHRM4;CHRM2;CHRM1 GO:0008284| positive regulation of cell proliferation CD86;CHRM1 27695:[DB01281 DB00648] DB01281|Abatacept CD80;CD86 DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0007165| signal transduction CD86;PGR;ESR1;AR GO:0006955| immune response CYP11B1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;ESR1;AR GO:0008284| positive regulation of cell proliferation CD86;AR 27696:[DB01281 DB02047] DB01281|Abatacept CD80;CD86 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways 27697:[DB01281 DB04879] DB01281|Abatacept CD80;CD86 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways GO:0016032| viral reproduction CD80;CD86;KDR GO:0008284| positive regulation of cell proliferation FLT1;FLT4;KDR;CD86 27698:[DB01281 DB02303] DB01281|Abatacept CD80;CD86 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways 27699:[DB01281 DB00004] DB01281|Abatacept CD80;CD86 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0002376| immune system process CD86;IL2RA GO:0007165| signal transduction CD86;IL2RB;IL2RG GO:0016032| viral reproduction CD80;IL2RG;CD86;IL2RB GO:0006955| immune response IL2RG;IL2RA;CD86 27700:[DB01281 DB05461] DB01281|Abatacept CD80;CD86 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0007165| signal transduction ADRA2B;ADRA2C;CD86;HTR2B GO:0008284| positive regulation of cell proliferation HTR2B;CD86 27701:[DB01281 DB04849] DB01281|Abatacept CD80;CD86 DB04849|Cediranib KDR common genes common pathways GO:0016032| viral reproduction CD86;KDR;CD80 GO:0008284| positive regulation of cell proliferation CD86;KDR 27702:[DB01281 DB02690] DB01281|Abatacept CD80;CD86 DB02690|NU1025 PARP1 common genes common pathways 27703:[DB01281 DB02901] DB01281|Abatacept CD80;CD86 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;AR;CD86 GO:0007165| signal transduction NR3C2;CD86;ESR1;AR 27704:[DB01281 DB00163] DB01281|Abatacept CD80;CD86 DB00163|Vitamin E NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;SEC14L4;SEC14L3;SEC14L2;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0035556| intracellular signal transduction PRKCA;HMOX1;DGKA;CD80;PRKCB GO:0007165| signal transduction PRKCB;CD86;NR1I2 GO:0045893| positive regulation of transcription, DNA-dependent CD80;SEC14L2;NR1I2;CD86 GO:0002250| adaptive immune response PRKCB;CD86 GO:0002376| immune system process CD86;PRKCB 27705:[DB01281 DB03910] DB01281|Abatacept CD80;CD86 DB03910|S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways 27706:[DB01281 DB06202] DB01281|Abatacept CD80;CD86 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86;ESR2 GO:0006955| immune response CD86;CNR2 GO:0007165| signal transduction CNR2;ESR1;ESR2;CD86 27707:[DB01281 DB08798] DB01281|Abatacept CD80;CD86 DB08798|Sulfamoxole CYP2C9 common genes common pathways 27708:[DB01281 DB05905] DB01281|Abatacept CD80;CD86 DB05905|TD-2749 HTR4 common genes common pathways GO:0007165| signal transduction HTR4;CD86 27709:[DB01281 DB07477] DB01281|Abatacept CD80;CD86 DB07477|Felbinac CTSL common genes common pathways GO:0002250| adaptive immune response CTSL;CD86 27710:[DB01281 DB04070] DB01281|Abatacept CD80;CD86 DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways 27711:[DB01281 DB00807] DB01281|Abatacept CD80;CD86 DB00807|Proparacaine SCN10A common genes common pathways 27712:[DB01281 DB01972] DB01281|Abatacept CD80;CD86 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0007165| signal transduction PDE5A;CD86;DLG4;HINT1 27713:[DB01281 DB01217] DB01281|Abatacept CD80;CD86 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways 27714:[DB01281 DB05662] DB01281|Abatacept CD80;CD86 DB05662|NP-50301 ESR1 common genes common pathways GO:0007165| signal transduction CD86;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86 27715:[DB01281 DB05511] DB01281|Abatacept CD80;CD86 DB05511|Piclidenoson ADORA3 common genes common pathways GO:0007165| signal transduction ADORA3;CD86 27716:[DB01281 DB06879] DB01281|Abatacept CD80;CD86 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways 27717:[DB01281 DB07637] DB01281|Abatacept CD80;CD86 DB07637|Dibromotyrosine EPOR common genes common pathways GO:0007165| signal transduction EPOR;CD86 27718:[DB01281 DB06791] DB01281|Abatacept CD80;CD86 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways GO:0007165| signal transduction SSTR5;CD86;SSTR2 27719:[DB01281 DB03158] DB01281|Abatacept CD80;CD86 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways GO:0007165| signal transduction CD86;INPP5B 27720:[DB01281 DB05202] DB01281|Abatacept CD80;CD86 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways 27721:[DB01281 DB01622] DB01281|Abatacept CD80;CD86 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;HTR2A;CD86 GO:0046718| entry of virus into host cell CD86;CD80;HTR2A GO:0007165| signal transduction ADRA1A;DRD2;CD86;HTR1A;HTR2A;ADRA1B;DRD1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A;DRD2 27722:[DB01281 DB09286] DB01281|Abatacept CD80;CD86 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0007165| signal transduction HTR2A;DRD4;DRD1;ADRA1B;DRD3;ADRA1D;CD86;ADRA2A;HTR2B;DRD2;ADRA1A GO:0046718| entry of virus into host cell CD80;HTR2A;CD86 GO:0016032| viral reproduction CD80;HTR2A;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0035556| intracellular signal transduction DRD2;ADRA1A;CD80;ADRA1B GO:0008284| positive regulation of cell proliferation HTR2A;HTR2B;ADRA2A;CD86;DRD3;ADRA1D 27723:[DB01281 DB00693] DB01281|Abatacept CD80;CD86 DB00693|Fluorescein CYP1A1;SLC22A6;ABCB11;ABCC1 common genes common pathways 27724:[DB01281 DB00780] DB01281|Abatacept CD80;CD86 DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways 27725:[DB01281 DB05188] DB01281|Abatacept CD80;CD86 DB05188|KD3010 PPARD common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PPARD;CD86 GO:0008284| positive regulation of cell proliferation CD86;PPARD 27726:[DB01281 DB05767] DB01281|Abatacept CD80;CD86 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0007165| signal transduction IL1B;CD86;NFKB2;NFKB1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation IL6;CD80 GO:0006955| immune response CD86;IL1B;IL6;TNF GO:0045086| positive regulation of interleukin-2 biosynthetic process IL1B;CD86;CD80 GO:0008284| positive regulation of cell proliferation IL1B;CD86;IL6 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;CD86;IL6;TNF;NFKB1;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;TNF 27727:[DB01281 DB06820] DB01281|Abatacept CD80;CD86 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways 27728:[DB01281 DB00871] DB01281|Abatacept CD80;CD86 DB00871|Terbutaline ADRB2;ADRB3;ADRB1;BCHE common genes common pathways GO:0007165| signal transduction ADRB1;CD86;ADRB3;ADRB2 27729:[DB01281 DB00500] DB01281|Abatacept CD80;CD86 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 27730:[DB01281 DB13869] DB01281|Abatacept CD80;CD86 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;CD86;ESR2 GO:0007165| signal transduction ESR1;ESR2;CD86 27731:[DB01281 DB08143] DB01281|Abatacept CD80;CD86 DB08143|5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;F10 27732:[DB01281 DB00804] DB01281|Abatacept CD80;CD86 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0007165| signal transduction CD86;CHRM2;CHRM1 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 27733:[DB01281 DB02820] DB01281|Abatacept CD80;CD86 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways 27734:[DB01281 DB09498] DB01281|Abatacept CD80;CD86 DB09498|Strontium chloride Sr-89 ALPPL2;ALPL;SLC8A1;CACNA1I common genes common pathways GO:0007165| signal transduction CACNA1I;CD86 27735:[DB01281 DB00223] DB01281|Abatacept CD80;CD86 DB00223|Diflorasone NR3C1 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 27736:[DB01281 DB02432] DB01281|Abatacept CD80;CD86 DB02432|RU90395 SRC common genes common pathways GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction CD86;SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0007165| signal transduction CD86;SRC GO:0045893| positive regulation of transcription, DNA-dependent CD86;SRC;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process CD86;SRC 27737:[DB01281 DB02481] DB01281|Abatacept CD80;CD86 DB02481|N-Benzylformamide ADH1B common genes common pathways 27738:[DB01281 DB00106] DB01281|Abatacept CD80;CD86 DB00106|Abarelix GNRHR common genes common pathways GO:0007165| signal transduction CD86;GNRHR 27739:[DB01281 DB00014] DB01281|Abatacept CD80;CD86 DB00014|Goserelin LHCGR;GNRHR common genes common pathways GO:0007165| signal transduction CD86;GNRHR;LHCGR 27740:[DB01281 DB14062] DB01281|Abatacept CD80;CD86 DB14062|Concanamycin A ABCB1 common genes common pathways 27741:[DB01281 DB14514] DB01281|Abatacept CD80;CD86 DB14514|Magnesium levulinate ATP1A1 common genes common pathways 27742:[DB01281 DB04278] DB01281|Abatacept CD80;CD86 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways GO:0006955| immune response IL2;CD86 GO:0002376| immune system process IL2;CD86 GO:0002250| adaptive immune response IL2;CD86 GO:0008284| positive regulation of cell proliferation IL2;CD86 27743:[DB01281 DB04787] DB01281|Abatacept CD80;CD86 DB04787|Tanaproget PGR common genes common pathways GO:0007165| signal transduction PGR;CD86 27744:[DB01281 DB07001] DB01281|Abatacept CD80;CD86 DB07001|(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine NOS3 common genes common pathways 27745:[DB01281 DB01116] DB01281|Abatacept CD80;CD86 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0007165| signal transduction CHRNA10;CD86 27746:[DB01281 DB11943] DB01281|Abatacept CD80;CD86 DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways 27747:[DB01281 DB00729] DB01281|Abatacept CD80;CD86 DB00729|Diphemanil Methylsulfate CHRM3 common genes common pathways GO:0007165| signal transduction CD86;CHRM3 27748:[DB01281 DB09086] DB01281|Abatacept CD80;CD86 DB09086|Eugenol ESR1;ESR2;AR;TRPV3 common genes common pathways GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR2;AR;ESR1;CD80 GO:0007165| signal transduction ESR2;CD86;ESR1;AR 27749:[DB01281 DB07675] DB01281|Abatacept CD80;CD86 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways GO:0007165| signal transduction CD86;PPARG GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 27750:[DB01281 DB05038] DB01281|Abatacept CD80;CD86 DB05038|Anatibant BDKRB2 common genes common pathways GO:0007165| signal transduction BDKRB2;CD86 27751:[DB01281 DB13975] DB01281|Abatacept CD80;CD86 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways 27752:[DB01281 DB07250] DB01281|Abatacept CD80;CD86 DB07250|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5- TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways 27753:[DB01281 DB06213] DB01281|Abatacept CD80;CD86 DB06213|Regadenoson ADORA2A common genes common pathways GO:0007165| signal transduction ADORA2A;CD86 27754:[DB01281 DB00042] DB01281|Abatacept CD80;CD86 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 27755:[DB01281 DB08386] DB01281|Abatacept CD80;CD86 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways GO:0007165| signal transduction CD86;PDE10A 27756:[DB01281 DB00891] DB01281|Abatacept CD80;CD86 DB00891|Sulfapyridine CYP2C9 common genes common pathways 27757:[DB01281 DB00254] DB01281|Abatacept CD80;CD86 DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0002376| immune system process B2M;PADI4;CD86 GO:0006955| immune response B2M;CD86 27758:[DB01281 DB04655] DB01281|Abatacept CD80;CD86 DB04655|Metoprine HNMT common genes common pathways 27759:[DB01281 DB08744] DB01281|Abatacept CD80;CD86 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways 27760:[DB01281 DB04253] DB01281|Abatacept CD80;CD86 DB04253|Tretazicar NQO2 common genes common pathways 27761:[DB01281 DB06314] DB01281|Abatacept CD80;CD86 DB06314|SGX-523 MET common genes common pathways GO:0007165| signal transduction CD86;MET GO:0051897| positive regulation of protein kinase B signaling cascade CD86;MET;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;MET;CD86 27762:[DB01281 DB06246] DB01281|Abatacept CD80;CD86 DB06246|Exisulind PDE4D;PDE4C;PDE5A;PDE2A;GSTP1;AKR1B1;AKR1B10 common genes common pathways GO:0007165| signal transduction PDE4D;PDE5A;PDE2A;PDE4C;CD86 27763:[DB01281 DB11811] DB01281|Abatacept CD80;CD86 DB11811|Arhalofenate PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;PPARG GO:0007165| signal transduction PPARG;CD86 27764:[DB01281 DB03227] DB01281|Abatacept CD80;CD86 DB03227|Nicotinamide Mononucleotide NMNAT1;NMNAT3;BST1;ligA common genes common pathways GO:0008284| positive regulation of cell proliferation BST1;CD86 GO:0007165| signal transduction CD86;BST1 27765:[DB01281 DB07385] DB01281|Abatacept CD80;CD86 DB07385|3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE NQO1 common genes common pathways 27766:[DB01281 DB11254] DB01281|Abatacept CD80;CD86 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0016032| viral reproduction CD80;TOP1;CD86 27767:[DB01281 DB14700] DB01281|Abatacept CD80;CD86 DB14700|Damoctocog alfa pegol F8 common genes common pathways 27768:[DB01281 DB01158] DB01281|Abatacept CD80;CD86 DB01158|Bretylium ATP1A1 common genes common pathways 27769:[DB01281 DB02336] DB01281|Abatacept CD80;CD86 DB02336|RU83876 SRC common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80;CD86 GO:0031295| T cell costimulation CD86;CD80;SRC GO:0002376| immune system process SRC;CD86 GO:0035556| intracellular signal transduction SRC;CD80 GO:0016032| viral reproduction CD86;CD80;SRC GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0007165| signal transduction CD86;SRC 27770:[DB01281 DB00418] DB01281|Abatacept CD80;CD86 DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0007165| signal transduction GRIA2;CHRNA4;CHRNA7;GABRA6;CD86;GABRA5 GO:0008284| positive regulation of cell proliferation CD86;CHRNA7 27771:[DB01281 DB06752] DB01281|Abatacept CD80;CD86 DB06752|Chymopapain PRG2 common genes common pathways GO:0002376| immune system process PRG2;CD86 GO:0006955| immune response PRG2;CD86 27772:[DB01281 DB09095] DB01281|Abatacept CD80;CD86 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction NR3C1;CD86 27773:[DB01281 DB02386] DB01281|Abatacept CD80;CD86 DB02386|Leucine Phosphonic Acid LAP3 common genes common pathways 27774:[DB01281 DB07903] DB01281|Abatacept CD80;CD86 DB07903|3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE METAP1 common genes common pathways 27775:[DB01281 DB06558] DB01281|Abatacept CD80;CD86 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;EDNRB GO:0007165| signal transduction EDNRA;CD86;EDNRB 27776:[DB01281 DB13915] DB01281|Abatacept CD80;CD86 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation CD80;CD19;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD19;CD86 27777:[DB01281 DB06623] DB01281|Abatacept CD80;CD86 DB06623|Flupirtine ADRA2A common genes common pathways GO:0007165| signal transduction ADRA2A;CD86 GO:0008284| positive regulation of cell proliferation CD86;ADRA2A 27778:[DB01281 DB05793] DB01281|Abatacept CD80;CD86 DB05793|PRO-542 FFAR4 common genes common pathways GO:0007165| signal transduction FFAR4;CD86 27779:[DB01281 DB09244] DB01281|Abatacept CD80;CD86 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways GO:0007165| signal transduction HTR1A;CD86;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA2A;CD86;HTR1A 27780:[DB01281 DB00387] DB01281|Abatacept CD80;CD86 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;CD86;CHRM4;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;CD86 27781:[DB01281 DB05133] DB01281|Abatacept CD80;CD86 DB05133|VP025 IL1B common genes common pathways GO:0006955| immune response IL1B;CD86 GO:0007165| signal transduction IL1B;CD86 GO:0045893| positive regulation of transcription, DNA-dependent IL1B;CD86;CD80 GO:0008284| positive regulation of cell proliferation CD86;IL1B GO:0045086| positive regulation of interleukin-2 biosynthetic process CD86;IL1B;CD80 27782:[DB01281 DB01235] DB01281|Abatacept CD80;CD86 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0035556| intracellular signal transduction DRD2;CD80 GO:0007165| signal transduction DRD3;DRD2;CD86;DRD4;DRD5;DRD1 GO:0008284| positive regulation of cell proliferation CD86;DRD3 27783:[DB01281 DB03742] DB01281|Abatacept CD80;CD86 DB03742|Compound 4-D ESR1 common genes common pathways GO:0007165| signal transduction ESR1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR1;CD80 27784:[DB01281 DB01278] DB01281|Abatacept CD80;CD86 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways GO:0007165| signal transduction CALCR;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CALCR;RAMP3;CD86 27785:[DB01281 DB02721] DB01281|Abatacept CD80;CD86 DB02721|4-Iodopyrazole ADH1C;ADH1B;ADH1A common genes common pathways 27786:[DB01281 DB01269] DB01281|Abatacept CD80;CD86 DB01269|Panitumumab EGFR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;EGFR;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD86;EGFR;CD80 GO:0008284| positive regulation of cell proliferation EGFR;CD86 GO:0046854| phosphatidylinositol phosphorylation CD80;CD86;EGFR GO:0035556| intracellular signal transduction EGFR;CD80 GO:0007165| signal transduction EGFR;CD86 GO:0046718| entry of virus into host cell CD80;EGFR;CD86 27787:[DB01281 DB09126] DB01281|Abatacept CD80;CD86 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways GO:0007165| signal transduction CD86;LHCGR 27788:[DB01281 DB05369] DB01281|Abatacept CD80;CD86 DB05369|HZT-501 HRH2 common genes common pathways GO:0006955| immune response CD86;HRH2 GO:0007165| signal transduction CD86;HRH2 27789:[DB01281 DB01348] DB01281|Abatacept CD80;CD86 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways 27790:[DB01281 DB00961] DB01281|Abatacept CD80;CD86 DB00961|Mepivacaine SCN10A common genes common pathways 27791:[DB01281 DB09186] DB01281|Abatacept CD80;CD86 DB09186|Nisoxetine SLC6A4 common genes common pathways 27792:[DB01281 DB04703] DB01281|Abatacept CD80;CD86 DB04703|Hesperidin AURKB common genes common pathways 27793:[DB01281 DB06825] DB01281|Abatacept CD80;CD86 DB06825|Triptorelin GNRHR common genes common pathways GO:0007165| signal transduction CD86;GNRHR 27794:[DB01281 DB07216] DB01281|Abatacept CD80;CD86 DB07216|(11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE FNTA;FNTB common genes common pathways 27795:[DB01281 DB01941] DB01281|Abatacept CD80;CD86 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways 27796:[DB01281 DB01565] DB01281|Abatacept CD80;CD86 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0006955| immune response CD86;OPRK1;OPRD1 GO:0007165| signal transduction OPRM1;OPRD1;POMC;TRIM13;OPRK1;CD86 27797:[DB01281 DB14575] DB01281|Abatacept CD80;CD86 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;P2RX4 27798:[DB01281 DB01694] DB01281|Abatacept CD80;CD86 DB01694|D-tartaric acid B3GAT1;TREM1;DDX6;HIF1AN;serA;lpxA;ATP6V1C1;phnA common genes common pathways GO:0035556| intracellular signal transduction CD80;TREM1 27799:[DB01281 DB07514] DB01281|Abatacept CD80;CD86 DB07514|3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one KDR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;KDR GO:0016032| viral reproduction KDR;CD86;CD80 27800:[DB01281 DB09270] DB01281|Abatacept CD80;CD86 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways GO:0016032| viral reproduction CD86;LDLR;CD80 GO:0007165| signal transduction VLDLR;CD86 GO:0046718| entry of virus into host cell CD86;LDLR;CD80 GO:0008284| positive regulation of cell proliferation CD86;HMGCR 27801:[DB01281 DB13149] DB01281|Abatacept CD80;CD86 DB13149|Protein S human F5;F10;PROC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 27802:[DB01281 DB07393] DB01281|Abatacept CD80;CD86 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways 27803:[DB01281 DB01839] DB01281|Abatacept CD80;CD86 DB01839|Propylene glycol F13A1 common genes common pathways 27804:[DB01281 DB05675] DB01281|Abatacept CD80;CD86 DB05675|EP-2104R FGA common genes common pathways GO:0007165| signal transduction FGA;CD86 GO:0002376| immune system process CD86;FGA GO:0002250| adaptive immune response FGA;CD86 27805:[DB01281 DB08996] DB01281|Abatacept CD80;CD86 DB08996|Dimetacrine ACHE common genes common pathways 27806:[DB01281 DB02262] DB01281|Abatacept CD80;CD86 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways 27807:[DB01281 DB03035] DB01281|Abatacept CD80;CD86 DB03035|1,8-Di-Hydroxy-4-Nitro-Anthraquinone CSNK2A1 common genes common pathways GO:0007165| signal transduction CSNK2A1;CD86 GO:0008284| positive regulation of cell proliferation CSNK2A1;CD86 27808:[DB01281 DB01135] DB01281|Abatacept CD80;CD86 DB01135|Doxacurium CHRNA2;CHRM2;BCHE common genes common pathways GO:0007165| signal transduction CD86;CHRM2;CHRNA2 27809:[DB01281 DB08084] DB01281|Abatacept CD80;CD86 DB08084|IDD594 AKR1B1 common genes common pathways 27810:[DB01281 DB03222] DB01281|Abatacept CD80;CD86 DB03222|dATP POLB;recA;recA common genes common pathways 27811:[DB01281 DB04776] DB01281|Abatacept CD80;CD86 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways 27812:[DB01281 DB07379] DB01281|Abatacept CD80;CD86 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways GO:0007165| signal transduction CD86;CDK6 27813:[DB01281 DB08601] DB01281|Abatacept CD80;CD86 DB08601|tributylstannanyl NCOA2;RXRA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;RXRA GO:0016032| viral reproduction CD80;CD86;RXRA 27814:[DB01281 DB07645] DB01281|Abatacept CD80;CD86 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways 27815:[DB01281 DB04660] DB01281|Abatacept CD80;CD86 DB04660|Choline alfoscerate GM2A common genes common pathways 27816:[DB01281 DB06494] DB01281|Abatacept CD80;CD86 DB06494|Sufugolix GNRHR common genes common pathways GO:0007165| signal transduction CD86;GNRHR 27817:[DB01281 DB07108] DB01281|Abatacept CD80;CD86 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways GO:0008284| positive regulation of cell proliferation BCL2L1;CD86 27818:[DB01281 DB08642] DB01281|Abatacept CD80;CD86 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways 27819:[DB01281 DB09409] DB01281|Abatacept CD80;CD86 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways 27820:[DB01281 DB00048] DB01281|Abatacept CD80;CD86 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;COL1A1;CD86 27821:[DB01281 DB00102] DB01281|Abatacept CD80;CD86 DB00102|Becaplermin PDGFRB;PDGFRA;A2M common genes common pathways GO:0035556| intracellular signal transduction CD80;PDGFRB GO:0016032| viral reproduction PDGFRA;CD86;CD80 GO:0007165| signal transduction PDGFRB;CD86 GO:0008284| positive regulation of cell proliferation PDGFRA;CD86;PDGFRB GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;PDGFRA;PDGFRB GO:0046854| phosphatidylinositol phosphorylation CD80;PDGFRB;CD86;PDGFRA 27822:[DB01281 DB00941] DB01281|Abatacept CD80;CD86 DB00941|Hexafluronium BCHE common genes common pathways 27823:[DB01281 DB02910] DB01281|Abatacept CD80;CD86 DB02910|Octanoyl-Coenzyme A ECHS1;ECI1;ACADM common genes common pathways 27824:[DB01281 DB04581] DB01281|Abatacept CD80;CD86 DB04581|1-benzylimidazole QPCT common genes common pathways 27825:[DB01281 DB02046] DB01281|Abatacept CD80;CD86 DB02046|N-[(Furan-2-Yl)Carbonyl]-(S)-Leucyl-(R)-[1-Amino-2(1h-Indol-3-Yl)Ethyl]-Phosphonic Acid ADAM28 common genes common pathways 27826:[DB01281 DB06264] DB01281|Abatacept CD80;CD86 DB06264|Tolperisone CYP1A2 common genes common pathways 27827:[DB01281 DB08378] DB01281|Abatacept CD80;CD86 DB08378|4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID MYL6B;MYL12A;MYH7 common genes common pathways 27828:[DB01281 DB01699] DB01281|Abatacept CD80;CD86 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways 27829:[DB01281 DB06937] DB01281|Abatacept CD80;CD86 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways GO:0007165| signal transduction ESR2;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;ESR2;CD80 27830:[DB01281 DB07800] DB01281|Abatacept CD80;CD86 DB07800|N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 27831:[DB01281 DB08169] DB01281|Abatacept CD80;CD86 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways 27832:[DB01281 DB06263] DB01281|Abatacept CD80;CD86 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways 27833:[DB01281 DB08709] DB01281|Abatacept CD80;CD86 DB08709|2,3-diphenyl-1H-indole-7-carboxylic acid PIM1 common genes common pathways 27834:[DB01281 DB03725] DB01281|Abatacept CD80;CD86 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways 27835:[DB01281 DB06938] DB01281|Abatacept CD80;CD86 DB06938|4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide KDR common genes common pathways GO:0016032| viral reproduction CD80;CD86;KDR GO:0008284| positive regulation of cell proliferation KDR;CD86 27836:[DB01281 DB05710] DB01281|Abatacept CD80;CD86 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways GO:0007165| signal transduction CHRNA3;CD86 27837:[DB01281 DB06809] DB01281|Abatacept CD80;CD86 DB06809|Plerixafor CXCR4 common genes common pathways GO:0016032| viral reproduction CXCR4;CD86;CD80 GO:0007165| signal transduction CD86;CXCR4 27838:[DB01281 DB02165] DB01281|Abatacept CD80;CD86 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways 27839:[DB01281 DB01082] DB01281|Abatacept CD80;CD86 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways GO:0002376| immune system process PADI4;CD86 27840:[DB01281 DB02824] DB01281|Abatacept CD80;CD86 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ODC1 27841:[DB01281 DB06757] DB01281|Abatacept CD80;CD86 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0002376| immune system process CD86;ARG1 GO:0002250| adaptive immune response CD86;ARG1 27842:[DB01281 DB14526] DB01281|Abatacept CD80;CD86 DB14526|Chromic citrate CYB5A;TF common genes common pathways 27843:[DB01281 DB01140] DB01281|Abatacept CD80;CD86 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways 27844:[DB01281 DB00121] DB01281|Abatacept CD80;CD86 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways 27845:[DB01281 DB05432] DB01281|Abatacept CD80;CD86 DB05432|DAS-431 IV CALY common genes common pathways 27846:[DB01281 DB08909] DB01281|Abatacept CD80;CD86 DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways 27847:[DB01281 DB13125] DB01281|Abatacept CD80;CD86 DB13125|Lusutrombopag MPL;CYP4A11;ABCB1;ABCG2 common genes common pathways 27848:[DB01281 DB05389] DB01281|Abatacept CD80;CD86 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways 27849:[DB01281 DB04901] DB01281|Abatacept CD80;CD86 DB04901|Galiximab CD80 common genes CD80 common pathways GO:0046854| phosphatidylinositol phosphorylation CD80;CD86 GO:0045086| positive regulation of interleukin-2 biosynthetic process CD86;CD80 GO:0031295| T cell costimulation CD80;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80 GO:0045425| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86 GO:0046718| entry of virus into host cell CD86;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80 GO:0016032| viral reproduction CD80;CD86 GO:0045627| positive regulation of T-helper 1 cell differentiation CD80 GO:0035556| intracellular signal transduction CD80 GO:0009967| positive regulation of signal transduction CD80 27850:[DB01281 DB06393] DB01281|Abatacept CD80;CD86 DB06393|Xaliproden HTR1A common genes common pathways GO:0007165| signal transduction HTR1A;CD86 GO:0008284| positive regulation of cell proliferation HTR1A;CD86 27851:[DB01281 DB00747] DB01281|Abatacept CD80;CD86 DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CHRM1 GO:0007165| signal transduction CHRM4;CD86;CHRM3;CHRNB2;CHRNA4;CHRM5;CHRM2;CHRM1 27852:[DB01281 DB04173] DB01281|Abatacept CD80;CD86 DB04173|Fructose FHIT common genes common pathways 27853:[DB01281 DB12582] DB01281|Abatacept CD80;CD86 DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;NR1I2;CD86 GO:0007165| signal transduction NR1I2;CD86 27854:[DB01281 DB04213] DB01281|Abatacept CD80;CD86 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways 27855:[DB01281 DB02869] DB01281|Abatacept CD80;CD86 DB02869|3-amino-5-phenylpentane CTSV;CTSK common genes common pathways 27856:[DB01281 DB03722] DB01281|Abatacept CD80;CD86 DB03722|3,4-Dihydro-5-Methyl-Isoquinolinone PARP1 common genes common pathways 27857:[DB01281 DB07232] DB01281|Abatacept CD80;CD86 DB07232|Veliparib PARP1;PARP2 common genes common pathways 27858:[DB01281 DB05855] DB01281|Abatacept CD80;CD86 DB05855|Rivanicline CHRNB2;CXCL8 common genes common pathways GO:0006955| immune response CXCL8;CD86 GO:0035556| intracellular signal transduction CD80;CXCL8 GO:0007165| signal transduction CXCL8;CD86;CHRNB2 27859:[DB01281 DB13909] DB01281|Abatacept CD80;CD86 DB13909|Bismuth subgallate ALB common genes common pathways 27860:[DB01281 DB03893] DB01281|Abatacept CD80;CD86 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways 27861:[DB01281 DB08262] DB01281|Abatacept CD80;CD86 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways 27862:[DB01281 DB08745] DB01281|Abatacept CD80;CD86 DB08745|4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;CD86;CD80 27863:[DB01281 DB01922] DB01281|Abatacept CD80;CD86 DB01922|Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam AMY2A;AMY2A common genes common pathways 27864:[DB01281 DB05122] DB01281|Abatacept CD80;CD86 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways GO:0046718| entry of virus into host cell CD80;ITGB7;CD86 27865:[DB01281 DB04065] DB01281|Abatacept CD80;CD86 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways 27866:[DB01281 DB09075] DB01281|Abatacept CD80;CD86 DB09075|Edoxaban F10;ABCB1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;CD86;CD80 27867:[DB01281 DB04720] DB01281|Abatacept CD80;CD86 DB04720|S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0007165| signal transduction CD86;CSNK2A1 GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 27868:[DB01281 DB00844] DB01281|Abatacept CD80;CD86 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0006955| immune response OPRD1;OPRK1;CD86 GO:0007165| signal transduction OPRM1;OPRD1;CD86;OPRK1 27869:[DB01281 DB07965] DB01281|Abatacept CD80;CD86 DB07965|6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)-ethyl]-9H-purine-2-carbonitrile CTSK common genes common pathways 27870:[DB01281 DB08689] DB01281|Abatacept CD80;CD86 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways 27871:[DB01281 DB01112] DB01281|Abatacept CD80;CD86 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways 27872:[DB01281 DB04453] DB01281|Abatacept CD80;CD86 DB04453|4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose AMY2A;AMY2A common genes common pathways 27873:[DB01281 DB05079] DB01281|Abatacept CD80;CD86 DB05079|HY10275 HRH1;HTR2A common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;HTR2A GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;HTR2A GO:0016032| viral reproduction CD86;CD80;HTR2A GO:0046718| entry of virus into host cell CD86;CD80;HTR2A GO:0007165| signal transduction CD86;HRH1;HTR2A 27874:[DB01281 DB05403] DB01281|Abatacept CD80;CD86 DB05403|CEP-1347 MAPK12 common genes common pathways GO:0007165| signal transduction MAPK12;CD86 27875:[DB01281 DB05961] DB01281|Abatacept CD80;CD86 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways GO:0002376| immune system process CD86;SERPING1 27876:[DB01281 DB04982] DB01281|Abatacept CD80;CD86 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways GO:0007165| signal transduction GRIA2;CD86;GRIA1 27877:[DB01281 DB11386] DB01281|Abatacept CD80;CD86 DB11386|Chlorobutanol KCNH2 common genes common pathways 27878:[DB01281 DB06021] DB01281|Abatacept CD80;CD86 DB06021|AV-412 EGFR;ERBB2 common genes common pathways GO:0046718| entry of virus into host cell CD86;EGFR;CD80 GO:0007165| signal transduction EGFR;CD86;ERBB2 GO:0035556| intracellular signal transduction EGFR;CD80 GO:0046854| phosphatidylinositol phosphorylation CD80;ERBB2;CD86;EGFR GO:0045893| positive regulation of transcription, DNA-dependent EGFR;CD86;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;ERBB2;CD86;EGFR GO:0008284| positive regulation of cell proliferation CD86;EGFR 27879:[DB01281 DB04869] DB01281|Abatacept CD80;CD86 DB04869|Olcegepant CALCA;CALCRL common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CALCRL GO:0007165| signal transduction CD86;CALCRL 27880:[DB01281 DB13951] DB01281|Abatacept CD80;CD86 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR1;CD80;AR;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR GO:0007165| signal transduction NR3C2;CD86;ESR1;AR 27881:[DB01281 DB09202] DB01281|Abatacept CD80;CD86 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;ADRA2A;ADRA1D GO:0007165| signal transduction ADRA1B;ADRA2C;ADRA2B;ADRA1A;ADRA2A;CD86;ADRA1D GO:0035556| intracellular signal transduction ADRA1B;CD80;ADRA1A 27882:[DB01281 DB09161] DB01281|Abatacept CD80;CD86 DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes common pathways 27883:[DB01281 DB00141] DB01281|Abatacept CD80;CD86 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways 27884:[DB01281 DB03904] DB01281|Abatacept CD80;CD86 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CTNNB1 GO:0002250| adaptive immune response ARG1;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;CTNNB1 GO:0002376| immune system process ARG1;CD86 27885:[DB01281 DB07177] DB01281|Abatacept CD80;CD86 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 27886:[DB01281 DB03793] DB01281|Abatacept CD80;CD86 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways 27887:[DB01281 DB02925] DB01281|Abatacept CD80;CD86 DB02925|Piretanide SLC12A1 common genes common pathways 27888:[DB01281 DB08232] DB01281|Abatacept CD80;CD86 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F7;CD86;F3;CD80 27889:[DB01281 DB13501] DB01281|Abatacept CD80;CD86 DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CD86 27890:[DB01281 DB02731] DB01281|Abatacept CD80;CD86 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways 27891:[DB01281 DB07984] DB01281|Abatacept CD80;CD86 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways 27892:[DB01281 DB13892] DB01281|Abatacept CD80;CD86 DB13892|Crotalus atrox antivenin PLA2G10;CYP4A11 common genes common pathways 27893:[DB01281 DB06480] DB01281|Abatacept CD80;CD86 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways GO:0007165| signal transduction CD86;HTR4 27894:[DB01281 DB04216] DB01281|Abatacept CD80;CD86 DB04216|Quercetin HCK;PIK3CG;UGT3A1;ATP5B;PIM1;HIBCH;fabZ;STK17B;ESR1;ESR2;NQO2;AHR;CYP1B1;ACTB;CSNK2A1;CSNK2B;EIF3F;HSP90AA1;HSPA2;RUVBL2;SF3B3;UBA1;SHBG;CBR1;CEBPB;NR1I2;CYP2C8;ALB;ABCC1;ABCC2;SLC16A7;SLCO2B1;ABCB1;SLC16A1;ABCG2;SLCO1B1 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation PIK3CG;CD86;CD80 GO:0002376| immune system process CD86;PIK3CG;HCK GO:0045893| positive regulation of transcription, DNA-dependent CD80;ESR1;CEBPB;AHR;NR1I2;ESR2;CD86 GO:0002250| adaptive immune response PIK3CG;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;PIK3CG GO:0008284| positive regulation of cell proliferation CSNK2A1;HCK;CD86 GO:0007165| signal transduction ESR1;CSNK2A1;CD86;ESR2;CSNK2B;NR1I2;HSP90AA1 GO:0006955| immune response CD86;CEBPB GO:0016032| viral reproduction HCK;CD80;CD86 GO:0035556| intracellular signal transduction CD80;STK17B 27895:[DB01281 DB07983] DB01281|Abatacept CD80;CD86 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways 27896:[DB01281 DB01616] DB01281|Abatacept CD80;CD86 DB01616|Alverine HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;CD86 GO:0007165| signal transduction HTR1A;CD86 27897:[DB01281 DB07769] DB01281|Abatacept CD80;CD86 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0008284| positive regulation of cell proliferation AR;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;CD80;AR GO:0007165| signal transduction AR;CD86 27898:[DB01281 DB01250] DB01281|Abatacept CD80;CD86 DB01250|Olsalazine TPMT;IFNG common genes common pathways GO:0002250| adaptive immune response IFNG;CD86 GO:0008284| positive regulation of cell proliferation IFNG;CD86 GO:0006955| immune response CD86;IFNG 27899:[DB01281 DB00881] DB01281|Abatacept CD80;CD86 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways 27900:[DB01281 DB07454] DB01281|Abatacept CD80;CD86 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;AR GO:0045893| positive regulation of transcription, DNA-dependent AR;CD80;CD86 GO:0007165| signal transduction AR;CD86 27901:[DB01281 DB08489] DB01281|Abatacept CD80;CD86 DB08489|N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YL)-SUCCINAMIDE MMP7 common genes common pathways 27902:[DB01281 DB09117] DB01281|Abatacept CD80;CD86 DB09117|Paraldehyde ALDH2 common genes common pathways 27903:[DB01281 DB00170] DB01281|Abatacept CD80;CD86 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0008284| positive regulation of cell proliferation F2;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F7;CD86;F10 27904:[DB01281 DB08577] DB01281|Abatacept CD80;CD86 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD86;FGFR1;CD80 GO:0008284| positive regulation of cell proliferation FGFR1;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;FGFR1;CD80 27905:[DB01281 DB01333] DB01281|Abatacept CD80;CD86 DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways 27906:[DB01281 DB07347] DB01281|Abatacept CD80;CD86 DB07347|4-(2-Aminoethyl)Benzenesulfonyl Fluoride GAPDH;ATP6V1B2 common genes common pathways 27907:[DB01281 DB01339] DB01281|Abatacept CD80;CD86 DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways GO:0007165| signal transduction CHRNA2;CD86 27908:[DB01281 DB03891] DB01281|Abatacept CD80;CD86 DB03891|1,5-Bis(N-Benzyloxycarbonyl-L-Leucinyl)Carbohydrazide CTSK common genes common pathways 27909:[DB01281 DB05214] DB01281|Abatacept CD80;CD86 DB05214|KD7040 NOS2 common genes common pathways 27910:[DB01281 DB03468] DB01281|Abatacept CD80;CD86 DB03468|1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide PNMT common genes common pathways 27911:[DB01281 DB00587] DB01281|Abatacept CD80;CD86 DB00587|Cinalukast CYSLTR1 common genes common pathways GO:0007165| signal transduction CYSLTR1;CD86 27912:[DB01281 DB05939] DB01281|Abatacept CD80;CD86 DB05939|MK-0354 GPER1 common genes common pathways GO:0007165| signal transduction CD86;GPER1 GO:0002376| immune system process GPER1;CD86 GO:0008284| positive regulation of cell proliferation GPER1;CD86 27913:[DB01281 DB00272] DB01281|Abatacept CD80;CD86 DB00272|Betazole HRH2 common genes common pathways GO:0006955| immune response CD86;HRH2 GO:0007165| signal transduction CD86;HRH2 27914:[DB01281 DB00952] DB01281|Abatacept CD80;CD86 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;CD86 GO:0007165| signal transduction HTR1B;CD86;HTR1F;HTR1D;HTR1A 27915:[DB01281 DB12662] DB01281|Abatacept CD80;CD86 DB12662|Naveglitazar PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 27916:[DB01281 DB03179] DB01281|Abatacept CD80;CD86 DB03179|Sinapoyl Coenzyme A COMTD1 common genes common pathways 27917:[DB01281 DB11328] DB01281|Abatacept CD80;CD86 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways 27918:[DB01281 DB00019] DB01281|Abatacept CD80;CD86 DB00019|Pegfilgrastim CSF3R;ELANE common genes common pathways GO:0007165| signal transduction CD86;CSF3R 27919:[DB01281 DB09147] DB01281|Abatacept CD80;CD86 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways 27920:[DB01281 DB00109] DB01281|Abatacept CD80;CD86 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways 27921:[DB01281 DB02371] DB01281|Abatacept CD80;CD86 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways GO:0002376| immune system process C1S;CD86 27922:[DB01281 DB02028] DB01281|Abatacept CD80;CD86 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways 27923:[DB01281 DB07209] DB01281|Abatacept CD80;CD86 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways GO:0007165| signal transduction PPARG;CD86 GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;PPARG 27924:[DB01281 DB08583] DB01281|Abatacept CD80;CD86 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;ABL1 27925:[DB01281 DB00646] DB01281|Abatacept CD80;CD86 DB00646|Nystatin CYP3A4;SLCO1B1;SLCO1B3 common genes common pathways 27926:[DB01281 DB08462] DB01281|Abatacept CD80;CD86 DB08462|N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE SRC common genes common pathways GO:0007165| signal transduction CD86;SRC GO:0035556| intracellular signal transduction SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation SRC;CD80 GO:0016032| viral reproduction CD80;SRC;CD86 GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation CD86;SRC;CD80 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;SRC;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;SRC;CD86 27927:[DB01281 DB00721] DB01281|Abatacept CD80;CD86 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0007165| signal transduction HTR3A;CD86;CHRNA2 GO:0002376| immune system process CD86;KCNN4 27928:[DB01281 DB14507] DB01281|Abatacept CD80;CD86 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0007165| signal transduction IMPA2;IMPA1;CD86 GO:0035556| intracellular signal transduction CD80;GSK3B GO:0046854| phosphatidylinositol phosphorylation IMPA2;CD86;IMPA1;CD80 27929:[DB01281 DB03932] DB01281|Abatacept CD80;CD86 DB03932|LFA703 ITGAL common genes common pathways GO:0007165| signal transduction CD86;ITGAL 27930:[DB01281 DB11071] DB01281|Abatacept CD80;CD86 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 27931:[DB01281 DB08191] DB01281|Abatacept CD80;CD86 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways GO:0035556| intracellular signal transduction SGK1;CD80 27932:[DB01281 DB13257] DB01281|Abatacept CD80;CD86 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;PCBD1;CD86 GO:0008284| positive regulation of cell proliferation CD86;PTGS2 GO:0006955| immune response CD86;FTH1 27933:[DB01281 DB05232] DB01281|Abatacept CD80;CD86 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways 27934:[DB01281 DB03851] DB01281|Abatacept CD80;CD86 DB03851|Carbazole Butanoic Acid FABP4 common genes common pathways 27935:[DB01281 DB08478] DB01281|Abatacept CD80;CD86 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways 27936:[DB01281 DB07931] DB01281|Abatacept CD80;CD86 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR1I2;CD86;CD80;ESR1 GO:0007165| signal transduction CD86;NR1I2;ESR1;NR1I3 27937:[DB01281 DB07112] DB01281|Abatacept CD80;CD86 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways 27938:[DB01281 DB01827] DB01281|Abatacept CD80;CD86 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways GO:0002376| immune system process LGALS3;CD86 27939:[DB01281 DB11219] DB01281|Abatacept CD80;CD86 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways GO:0007165| signal transduction CD86;ESR2;PGR;AR;ESR1 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CD80;ESR2;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR 27940:[DB01281 DB03732] DB01281|Abatacept CD80;CD86 DB03732|Etheno-Nadp BST1 common genes common pathways GO:0007165| signal transduction BST1;CD86 GO:0008284| positive regulation of cell proliferation BST1;CD86 27941:[DB01281 DB05183] DB01281|Abatacept CD80;CD86 DB05183|MLN0415 IKBKB common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;IKBKB;CD86 27942:[DB01281 DB03382] DB01281|Abatacept CD80;CD86 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways 27943:[DB01281 DB06637] DB01281|Abatacept CD80;CD86 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways 27944:[DB01281 DB08790] DB01281|Abatacept CD80;CD86 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways GO:0007165| signal transduction HPGDS;CD86 27945:[DB01281 DB07940] DB01281|Abatacept CD80;CD86 DB07940|9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE BCHE common genes common pathways 27946:[DB01281 DB03935] DB01281|Abatacept CD80;CD86 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways GO:0007165| signal transduction ANXA5;FGF2;CD86 GO:0046854| phosphatidylinositol phosphorylation CD86;FGF2;CD80 GO:0008284| positive regulation of cell proliferation CD86;FGF2 GO:0051897| positive regulation of protein kinase B signaling cascade CD86;CD80;FGF2 GO:0045893| positive regulation of transcription, DNA-dependent FGF2;CD80;CD86 27947:[DB01281 DB00722] DB01281|Abatacept CD80;CD86 DB00722|Lisinopril ACE common genes common pathways 27948:[DB01281 DB01746] DB01281|Abatacept CD80;CD86 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways 27949:[DB01281 DB08052] DB01281|Abatacept CD80;CD86 DB08052|1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade SRC;CD80;CD86 GO:0045893| positive regulation of transcription, DNA-dependent SRC;CD80;CD86 GO:0002376| immune system process CD86;SRC GO:0031295| T cell costimulation CD80;SRC;CD86 GO:0035556| intracellular signal transduction CD80;SRC GO:0016032| viral reproduction CD86;SRC;CD80 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;SRC GO:0007165| signal transduction CD86;SRC 27950:[DB01281 DB09031] DB01281|Abatacept CD80;CD86 DB09031|Miltefosine ABCB1;PLD1 common genes common pathways 27951:[DB01281 DB08429] DB01281|Abatacept CD80;CD86 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways GO:0031295| T cell costimulation DPP4;CD86;CD80 GO:0008284| positive regulation of cell proliferation DPP4;CD86 GO:0046718| entry of virus into host cell CD86;DPP4;CD80 27952:[DB01281 DB02217] DB01281|Abatacept CD80;CD86 DB02217|Dpb-T NT5M common genes common pathways 27953:[DB01281 DB01406] DB01281|Abatacept CD80;CD86 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0006955| immune response CD86;CCL2 GO:0007165| signal transduction ESR1;AR;CCL2;GNRHR;CD86;PGR;GNRHR2 GO:0045893| positive regulation of transcription, DNA-dependent AR;ESR1;CD80;CD86 GO:0008284| positive regulation of cell proliferation CD86;AR 27954:[DB01281 DB09552] DB01281|Abatacept CD80;CD86 DB09552|Thonzonium ATP6V1C1 common genes common pathways 27955:[DB01281 DB03480] DB01281|Abatacept CD80;CD86 DB03480|Brequinar Analog DHODH common genes common pathways 27956:[DB01281 DB04531] DB01281|Abatacept CD80;CD86 DB04531|Benzylcysteine MGMT common genes common pathways 27957:[DB01281 DB01625] DB01281|Abatacept CD80;CD86 DB01625|Isopropamide CHRM3;CHRM4 common genes common pathways GO:0007165| signal transduction CHRM4;CD86;CHRM3 27958:[DB01281 DB05035] DB01281|Abatacept CD80;CD86 DB05035|Eprotirome THRA;THRB common genes common pathways 27959:[DB01281 DB03782] DB01281|Abatacept CD80;CD86 DB03782|N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea PLAU common genes common pathways GO:0007165| signal transduction CD86;PLAU 27960:[DB01281 DB06729] DB01281|Abatacept CD80;CD86 DB06729|Sulfaphenazole CYP2C9;CYP2B6;CYP2C8;CYP2D6 common genes common pathways 27961:[DB01281 DB01684] DB01281|Abatacept CD80;CD86 DB01684|1-Hydroxy-1-Thio-Glycerol PREP common genes common pathways 27962:[DB01281 DB11079] DB01281|Abatacept CD80;CD86 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;PTGS2 27963:[DB01281 DB02300] DB01281|Abatacept CD80;CD86 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0007165| signal transduction CD86;VDR 27964:[DB01281 DB08437] DB01281|Abatacept CD80;CD86 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;RPL23 27965:[DB01281 DB08313] DB01281|Abatacept CD80;CD86 DB08313|nocodazole HPGDS common genes common pathways GO:0007165| signal transduction HPGDS;CD86 27966:[DB01281 DB04752] DB01281|Abatacept CD80;CD86 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent NR5A1;CD80;CD86 27967:[DB01281 DB12747] DB01281|Abatacept CD80;CD86 DB12747|Tertomotide TERT common genes common pathways 27968:[DB01281 DB13170] DB01281|Abatacept CD80;CD86 DB13170|Plecanatide GUCY1A2 common genes common pathways GO:0007165| signal transduction GUCY1A2;CD86 GO:0035556| intracellular signal transduction CD80;GUCY1A2 27969:[DB01281 DB00436] DB01281|Abatacept CD80;CD86 DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways 27970:[DB01281 DB03983] DB01281|Abatacept CD80;CD86 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways 27971:[DB01281 DB00953] DB01281|Abatacept CD80;CD86 DB00953|Rizatriptan HTR1D;HTR1B;HTR1F;MAOA common genes common pathways GO:0007165| signal transduction HTR1F;CD86;HTR1B;HTR1D 27972:[DB01281 DB07974] DB01281|Abatacept CD80;CD86 DB07974|1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;F10;CD86 27973:[DB01281 DB13983] DB01281|Abatacept CD80;CD86 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0007165| signal transduction GABRA6;GABRA5;CD86 27974:[DB01281 DB08383] DB01281|Abatacept CD80;CD86 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways GO:0007165| signal transduction CD86;PDE10A 27975:[DB01281 DB02895] DB01281|Abatacept CD80;CD86 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways 27976:[DB01281 DB06766] DB01281|Abatacept CD80;CD86 DB06766|Alcaftadine HRH1 common genes common pathways GO:0007165| signal transduction HRH1;CD86 27977:[DB01281 DB02967] DB01281|Abatacept CD80;CD86 DB02967|N-Ethylmaleimide CLC common genes common pathways 27978:[DB01281 DB00484] DB01281|Abatacept CD80;CD86 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0007165| signal transduction ADRA2A;CD86;ADRA2C;ADRA2B GO:0008284| positive regulation of cell proliferation ADRA2A;CD86 27979:[DB01281 DB01954] DB01281|Abatacept CD80;CD86 DB01954|Rolipram PDE4D;PDE4B common genes common pathways GO:0007165| signal transduction CD86;PDE4B;PDE4D 27980:[DB01281 DB05207] DB01281|Abatacept CD80;CD86 DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0007165| signal transduction IL1R1;CD86 GO:0006955| immune response CD86;IL1R1;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;CD86;CD80 GO:0045893| positive regulation of transcription, DNA-dependent CD80;TNF;CD86 27981:[DB01281 DB06677] DB01281|Abatacept CD80;CD86 DB06677|Clazosentan EDNRA common genes common pathways GO:0007165| signal transduction CD86;EDNRA 27982:[DB01281 DB04258] DB01281|Abatacept CD80;CD86 DB04258|Seocalcitol VDR common genes common pathways GO:0007165| signal transduction CD86;VDR 27983:[DB01281 DB01188] DB01281|Abatacept CD80;CD86 DB01188|Ciclopirox ATP1A1 common genes common pathways 27984:[DB01281 DB11221] DB01281|Abatacept CD80;CD86 DB11221|Dioxybenzone SHBG common genes common pathways 27985:[DB01281 DB06548] DB01281|Abatacept CD80;CD86 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0016032| viral reproduction CD86;FDPS;CD80 27986:[DB01281 DB11098] DB01281|Abatacept CD80;CD86 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways 27987:[DB01281 DB00045] DB01281|Abatacept CD80;CD86 DB00045|Lyme disease vaccine (recombinant OspA) TLR2 common genes common pathways GO:0007165| signal transduction TLR2;CD86 GO:0006955| immune response CD86;TLR2 GO:0002376| immune system process CD86;TLR2 27988:[DB01281 DB01944] DB01281|Abatacept CD80;CD86 DB01944|(S)-blebbistatin MYH14 common genes common pathways 27989:[DB01281 DB04372] DB01281|Abatacept CD80;CD86 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 27990:[DB01281 DB00905] DB01281|Abatacept CD80;CD86 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;AKR1C3;CD86 GO:0008284| positive regulation of cell proliferation CD86;PTGFR;AKR1C3 GO:0007165| signal transduction CD86;PTGFR;PTGER1;PTGER3 27991:[DB01281 DB00466] DB01281|Abatacept CD80;CD86 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways 27992:[DB01281 DB01078] DB01281|Abatacept CD80;CD86 DB01078|Deslanoside ATP1A1 common genes common pathways 27993:[DB01281 DB09139] DB01281|Abatacept CD80;CD86 DB09139|Technetium Tc-99m oxidronate ALB common genes common pathways 27994:[DB01281 DB11945] DB01281|Abatacept CD80;CD86 DB11945|Avelumab CD274 common genes common pathways GO:0006955| immune response CD86;CD274 GO:0007165| signal transduction CD274;CD86 GO:0031295| T cell costimulation CD80;CD274;CD86 27995:[DB01281 DB01786] DB01281|Abatacept CD80;CD86 DB01786|D-Alanine SLC16A10 common genes common pathways 27996:[DB01281 DB04451] DB01281|Abatacept CD80;CD86 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways 27997:[DB01281 DB02101] DB01281|Abatacept CD80;CD86 DB02101|(S,R)-fidarestat AKR1B1 common genes common pathways 27998:[DB01281 DB01225] DB01281|Abatacept CD80;CD86 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;CD86;CD80 27999:[DB01281 DB06258] DB01281|Abatacept CD80;CD86 DB06258|Bimoclomol HSF1 common genes common pathways GO:0008284| positive regulation of cell proliferation HSF1;CD86 28000:[DB01281 DB01260] DB01281|Abatacept CD80;CD86 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction CD86;NR3C1 28001:[DB01281 DB05624] DB01281|Abatacept CD80;CD86 DB05624|Teverelix GNRHR common genes common pathways GO:0007165| signal transduction GNRHR;CD86 28002:[DB01281 DB02929] DB01281|Abatacept CD80;CD86 DB02929|K201 ANXA5 common genes common pathways GO:0007165| signal transduction CD86;ANXA5 28003:[DB01281 DB04020] DB01281|Abatacept CD80;CD86 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESR2;CD86;CD80 GO:0007165| signal transduction CD86;ESR2 28004:[DB01281 DB07256] DB01281|Abatacept CD80;CD86 DB07256|3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE EPHB4 common genes common pathways 28005:[DB01281 DB05119] DB01281|Abatacept CD80;CD86 DB05119|Rilapladib PLA2G7 common genes common pathways 28006:[DB01281 DB07723] DB01281|Abatacept CD80;CD86 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD86;PPARG;CD80 GO:0007165| signal transduction CD86;PPARG 28007:[DB01281 DB08038] DB01281|Abatacept CD80;CD86 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 28008:[DB01281 DB04711] DB01281|Abatacept CD80;CD86 DB04711|Iodipamide ALB common genes common pathways 28009:[DB01281 DB03510] DB01281|Abatacept CD80;CD86 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways GO:0002376| immune system process ADSSL1;CD86 28010:[DB01281 DB04830] DB01281|Abatacept CD80;CD86 DB04830|Buformin SLC22A1 common genes common pathways 28011:[DB01281 DB04664] DB01281|Abatacept CD80;CD86 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways 28012:[DB01281 DB01535] DB01281|Abatacept CD80;CD86 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007165| signal transduction OPRD1;OPRM1;CD86;OPRK1 GO:0006955| immune response CD86;OPRK1;OPRD1 28013:[DB01281 DB04534] DB01281|Abatacept CD80;CD86 DB04534|5-Nitroindazole NOS2;NOS3 common genes common pathways 28014:[DB01281 DB08480] DB01281|Abatacept CD80;CD86 DB08480|4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN MAOB common genes common pathways 28015:[DB01281 DB06897] DB01281|Abatacept CD80;CD86 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways 28016:[DB01281 DB05150] DB01281|Abatacept CD80;CD86 DB05150|CAD106 APP common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD80;APP;CD86 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;APP 28017:[DB01281 DB01381] DB01281|Abatacept CD80;CD86 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways 28018:[DB01281 DB01208] DB01281|Abatacept CD80;CD86 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways 28019:[DB01281 DB01686] DB01281|Abatacept CD80;CD86 DB01686|N,N-dimethylarginine NOS2;NOS3 common genes common pathways 28020:[DB01281 DB13083] DB01281|Abatacept CD80;CD86 DB13083|Talarozole CYP26A1 common genes common pathways 28021:[DB01281 DB04287] DB01281|Abatacept CD80;CD86 DB04287|(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid PLA2G2A common genes common pathways 28022:[DB01281 DB08354] DB01281|Abatacept CD80;CD86 DB08354|2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation CD86;CSNK2A1 GO:0007165| signal transduction CSNK2A1;CD86 28023:[DB01281 DB00403] DB01281|Abatacept CD80;CD86 DB00403|Ceruletide CCKAR common genes common pathways GO:0007165| signal transduction CCKAR;CD86 28024:[DB01281 DB04150] DB01281|Abatacept CD80;CD86 DB04150|Threonine Derivative PAM common genes common pathways 28025:[DB01281 DB04716] DB01281|Abatacept CD80;CD86 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways GO:0035556| intracellular signal transduction JAK3;CD80;TYK2;DAPK3;JAK2;JAK1 GO:0050731| positive regulation of peptidyl-tyrosine phosphorylation CD80;JAK2 GO:0007165| signal transduction JAK2;CD86 GO:0008284| positive regulation of cell proliferation CD86;JAK2 GO:0002250| adaptive immune response JAK2;CD86;JAK3 GO:0002376| immune system process JAK3;JAK2;CD86 28026:[DB01281 DB06835] DB01281|Abatacept CD80;CD86 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 28027:[DB01281 DB01003] DB01281|Abatacept CD80;CD86 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways 28028:[DB01281 DB05311] DB01281|Abatacept CD80;CD86 DB05311|Ecallantide KLKB1 common genes common pathways 28029:[DB01281 DB11597] DB01281|Abatacept CD80;CD86 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 28030:[DB01281 DB07033] DB01281|Abatacept CD80;CD86 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways GO:0035556| intracellular signal transduction CD80;PDPK1 GO:0031295| T cell costimulation PDPK1;CD86;CD80 28031:[DB01281 DB06902] DB01281|Abatacept CD80;CD86 DB06902|4-(1-methyl-1-phenylethyl)phenol ESRRG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent ESRRG;CD86;CD80 28032:[DB01281 DB11740] DB01281|Abatacept CD80;CD86 DB11740|MK-1775 WEE1 common genes common pathways 28033:[DB01281 DB03408] DB01281|Abatacept CD80;CD86 DB03408|gamma-Glutamylcysteine GSS common genes common pathways 28034:[DB01281 DB04209] DB01281|Abatacept CD80;CD86 DB04209|Dequalinium XIAP;CNGA1;KCNMA1 common genes common pathways GO:0007165| signal transduction CD86;CNGA1 28035:[DB01281 DB01830] DB01281|Abatacept CD80;CD86 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways GO:0016032| viral reproduction CD80;CD86;LCK GO:0051897| positive regulation of protein kinase B signaling cascade CD80;CD86;LCK GO:0031295| T cell costimulation CD86;LCK;CD80 GO:0046854| phosphatidylinositol phosphorylation LCK;CD86;CD80 28036:[DB01281 DB11475] DB01281|Abatacept CD80;CD86 DB11475|Tylosin CYP3A4 common genes common pathways 28037:[DB01281 DB08933] DB01281|Abatacept CD80;CD86 DB08933|Luliconazole CYP3A4;CYP2C19 common genes common pathways 28038:[DB01281 DB05465] DB01281|Abatacept CD80;CD86 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0008284| positive regulation of cell proliferation FLT3;PDGFD;CD86 28039:[DB01281 DB11632] DB01281|Abatacept CD80;CD86 DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes common pathways 28040:[DB01281 DB02398] DB01281|Abatacept CD80;CD86 DB02398|6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0007165| signal transduction PLAU;CD86 28041:[DB01281 DB00181] DB01281|Abatacept CD80;CD86 DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways GO:0007165| signal transduction GABBR1;GABBR2;CD86 28042:[DB01281 DB02676] DB01281|Abatacept CD80;CD86 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways GO:0007165| signal transduction PDE4D;CD86 28043:[DB01281 DB02555] DB01281|Abatacept CD80;CD86 DB02555|SP4160 IL2 common genes common pathways GO:0002376| immune system process IL2;CD86 GO:0002250| adaptive immune response CD86;IL2 GO:0008284| positive regulation of cell proliferation IL2;CD86 GO:0006955| immune response CD86;IL2 28044:[DB01281 DB08891] DB01281|Abatacept CD80;CD86 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways GO:0007165| signal transduction GABBR2;CD86;GABBR1 28045:[DB01281 DB08618] DB01281|Abatacept CD80;CD86 DB08618|3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER IGHG2 common genes common pathways GO:0002250| adaptive immune response IGHG2;CD86 GO:0002376| immune system process CD86;IGHG2 28046:[DB01281 DB11674] DB01281|Abatacept CD80;CD86 DB11674|Equol ESR2;SHBG common genes common pathways GO:0045893| positive regulation of transcription, DNA-dependent CD80;CD86;ESR2 GO:0007165| signal transduction CD86;ESR2 28047:[DB01281 DB01884] DB01281|Abatacept CD80;CD86 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways GO:0046718| entry of virus into host cell CD80;DPP4;CD86 GO:0008284| positive regulation of cell proliferation CD86;DPP4 GO:0031295| T cell costimulation CD80;DPP4;CD86 28048:[DB01281 DB04677] DB01281|Abatacept CD80;CD86 DB04677|N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE MAOB common genes common pathways 28049:[DB01281 DB01060] DB01281|Abatacept CD80;CD86 DB01060|Amoxicillin CYP2C19;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 28050:[DB01281 DB06160] DB01281|Abatacept CD80;CD86 DB06160|Garenoxacin CYP1A2 common genes common pathways 28051:[DB01281 DB04079] DB01281|Abatacept CD80;CD86 DB04079|Heptane-1,2,3-Triol RHO common genes common pathways GO:0007165| signal transduction RHO;CD86 28052:[DB01281 DB03087] DB01281|Abatacept CD80;CD86 DB03087|2-(Sec-Butyl)Thiazole LCN9 common genes common pathways 28053:[DB01281 DB08855] DB01281|Abatacept CD80;CD86 DB08855|Leukotriene C4 CYSLTR1;CYSLTR2;ABCC1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006955| immune response CD86;CYSLTR2 GO:0007165| signal transduction CD86;CYSLTR1;CYSLTR2 28054:[DB01281 DB03881] DB01281|Abatacept CD80;CD86 DB03881|MT-Immucillin-H PNP common genes common pathways GO:0006955| immune response PNP;CD86 28055:[DB01281 DB01276] DB01281|Abatacept CD80;CD86 DB01276|Exenatide GLP1R;ALB common genes common pathways GO:0007165| signal transduction GLP1R;CD86 28056:[DB01281 DB14040] DB01281|Abatacept CD80;CD86 DB14040|Eptinezumab CALCA;CALCB common genes common pathways GO:0007165| signal transduction CALCB;CD86 28057:[DB01281 DB01949] DB01281|Abatacept CD80;CD86 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 28058:[DB01281 DB05217] DB01281|Abatacept CD80;CD86 DB05217|GMX1777 NAMPT common genes common pathways GO:0008284| positive regulation of cell proliferation NAMPT;CD86 GO:0007165| signal transduction NAMPT;CD86 28059:[DB01281 DB03632] DB01281|Abatacept CD80;CD86 DB03632|Argifin CHIT1 common genes common pathways GO:0006955| immune response CD86;CHIT1 28060:[DB06728 DB07543] DB06728|Aniline KLK1;ALB;CYP2E1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB 28061:[DB06728 DB11730] DB06728|Aniline KLK1;ALB;CYP2E1 DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28062:[DB06728 DB00504] DB06728|Aniline KLK1;ALB;CYP2E1 DB00504|Levallorphan OPRM1 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1 28063:[DB06728 DB00413] DB06728|Aniline KLK1;ALB;CYP2E1 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0042493| response to drug DRD3;HTR2B;HTR2C;DRD2;HTR1B;CYP2E1;HTR2A;DRD1 GO:0045471| response to ethanol DRD2;HTR1B;DRD3;CYP2E1 28064:[DB06728 DB03685] DB06728|Aniline KLK1;ALB;CYP2E1 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways 28065:[DB06728 DB01224] DB06728|Aniline KLK1;ALB;CYP2E1 DB01224|Quetiapine HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP3A4;CYP2C19;CYP2D6;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0042493| response to drug HTR1B;ABCB1;DRD2;ADRA1A;HTR2C;DRD3;DRD1;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP2D6;CYP2C19;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP3A5;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A7 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;HTR3A;HTR1B;DRD2;DRD3 28066:[DB06728 DB07926] DB06728|Aniline KLK1;ALB;CYP2E1 DB07926|N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE MMP1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;MMP1 GO:0006508| proteolysis KLK1;MMP1 28067:[DB06728 DB07218] DB06728|Aniline KLK1;ALB;CYP2E1 DB07218|6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE MAPK8IP1;MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process MAPK8;ALB;MAPK8IP1 28068:[DB06728 DB06605] DB06728|Aniline KLK1;ALB;CYP2E1 DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0006508| proteolysis F10;KLK1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP2J2;CYP3A4;CYP3A5;CYP2C19;CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2C8;CYP2C19 GO:0042493| response to drug CYP2E1;CYP1A2;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP2J2;CYP3A4;CYP1A2;CYP2C9;CYP3A5;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2J2;CYP2C9;CYP2C19;CYP2C8 28069:[DB06728 DB01179] DB06728|Aniline KLK1;ALB;CYP2E1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0002576| platelet degranulation ALB;TUBA4A 28070:[DB06728 DB05127] DB06728|Aniline KLK1;ALB;CYP2E1 DB05127|ANA971 TLR7 common genes common pathways 28071:[DB06728 DB03372] DB06728|Aniline KLK1;ALB;CYP2E1 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0045471| response to ethanol CYP2E1;IL2 28072:[DB06728 DB02059] DB06728|Aniline KLK1;ALB;CYP2E1 DB02059|Adenosine-5-Diphosphoribose EEF2;GAPDH;SIRT5;SIRT3 common genes common pathways GO:0045471| response to ethanol CYP2E1;EEF2 GO:0055114| oxidation-reduction process GAPDH;CYP2E1 GO:0042493| response to drug EEF2;CYP2E1 28073:[DB06728 DB01148] DB06728|Aniline KLK1;ALB;CYP2E1 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways 28074:[DB06728 DB01594] DB06728|Aniline KLK1;ALB;CYP2E1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 28075:[DB06728 DB06698] DB06728|Aniline KLK1;ALB;CYP2E1 DB06698|Betahistine HRH1;HRH3 common genes common pathways 28076:[DB06728 DB00645] DB06728|Aniline KLK1;ALB;CYP2E1 DB00645|Dyclonine SCN10A common genes common pathways 28077:[DB06728 DB09213] DB06728|Aniline KLK1;ALB;CYP2E1 DB09213|Dexibuprofen PTGS2;PTGS1;BCL2;THBD;PLAT;FABP2;PPARG;CFTR;SLC15A1;PPARA;GP1BA;S100A7;CYP2C9;UGT1A1;UGT1A3;UGT1A9;UGT2B4;UGT2B7;CYP2C8;CYP2C19;AMACR;ALB;ABCC4;ABCC1;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLCO2B1;ABCB1 common genes ALB common pathways GO:0042493| response to drug BCL2;PTGS2;CYP2E1;ABCC4;ABCC1;UGT1A1;PPARG;ABCB1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process ABCC4;PTGS1;PTGS2;CYP2E1;CYP2C19;CYP2C8;CYP2C9 GO:0010243| response to organic nitrogen ABCC4;CYP2E1;PTGS2 GO:0002576| platelet degranulation ABCC4;ALB GO:0043066| negative regulation of apoptotic process PTGS2;BCL2;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO2B1;ALB GO:0008202| steroid metabolic process CYP2E1;UGT2B7;UGT1A1;CYP2C9;CYP2C19;CYP2C8 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLC22A6;SLC22A11;SLCO1A2;SLC22A8 GO:0009267| cellular response to starvation ALB GO:0098869| ALB;PTGS1;PTGS2 GO:0017144| drug metabolic process UGT1A9;UGT1A1;CYP2C9;CYP2C19;CYP2C8;CYP2E1;UGT1A3 GO:0006508| proteolysis PLAT;KLK1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2C9;UGT2B4;UGT1A9;PTGS1;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB 28078:[DB06728 DB06725] DB06728|Aniline KLK1;ALB;CYP2E1 DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;PTGS1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0098869| ALB;PTGS1;PTGS2 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 28079:[DB06728 DB04863] DB06728|Aniline KLK1;ALB;CYP2E1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0002576| platelet degranulation ITGA2B;ITGB3;ALB 28080:[DB06728 DB00232] DB06728|Aniline KLK1;ALB;CYP2E1 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways 28081:[DB06728 DB01580] DB06728|Aniline KLK1;ALB;CYP2E1 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 28082:[DB06728 DB00725] DB06728|Aniline KLK1;ALB;CYP2E1 DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways 28083:[DB06728 DB00838] DB06728|Aniline KLK1;ALB;CYP2E1 DB00838|Clocortolone NR3C1 common genes common pathways 28084:[DB06728 DB04722] DB06728|Aniline KLK1;ALB;CYP2E1 DB04722|2-(3-CHLORO-6-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-1-OXIDOPYRIDIN-2-YL)-N-[1-(3-CHLOROPHENYL)ETHYL]ACETAMIDE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 28085:[DB06728 DB00196] DB06728|Aniline KLK1;ALB;CYP2E1 DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP11B1;CYP3A7;CYP2C9;CYP2C19;CYP3A5 GO:0042493| response to drug CYP2E1;ABCB1 GO:0008202| steroid metabolic process CYP2C9;CYP2C19;CYP3A5;CYP3A4;CYP2E1;CYP11B1;CYP3A7 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2C19;CYP2C9 28086:[DB06728 DB06935] DB06728|Aniline KLK1;ALB;CYP2E1 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 28087:[DB06728 DB04311] DB06728|Aniline KLK1;ALB;CYP2E1 DB04311|4-Phenylbutylamine PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 28088:[DB06728 DB02789] DB06728|Aniline KLK1;ALB;CYP2E1 DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process NR1I2;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLC10A6;ALB GO:0008202| steroid metabolic process NR1I2;SULT2B1;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 28089:[DB06728 DB01833] DB06728|Aniline KLK1;ALB;CYP2E1 DB01833|L-2-Amino-4-(Guanidinooxy)Butyric Acid NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS3 28090:[DB06728 DB08911] DB06728|Aniline KLK1;ALB;CYP2E1 DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2E1 28091:[DB06728 DB00087] DB06728|Aniline KLK1;ALB;CYP2E1 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0006508| proteolysis C1QA;KLK1;C1QC;C1R;C1QB 28092:[DB06728 DB08128] DB06728|Aniline KLK1;ALB;CYP2E1 DB08128|(1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine PNMT common genes common pathways 28093:[DB06728 DB03439] DB06728|Aniline KLK1;ALB;CYP2E1 DB03439|4,6-dideoxy-4-amino-alpha-D-glucose AMY1A;AMY2A;AMY2A common genes common pathways 28094:[DB06728 DB04925] DB06728|Aniline KLK1;ALB;CYP2E1 DB04925|Desmoteplase PLG common genes common pathways GO:0002576| platelet degranulation PLG;ALB GO:0044267| cellular protein metabolic process PLG;ALB GO:0006508| proteolysis KLK1;PLG 28095:[DB06728 DB06981] DB06728|Aniline KLK1;ALB;CYP2E1 DB06981|(2S)-2-(1H-indol-3-yl)pentanoic acid SKP1 common genes common pathways GO:0043687| post-translational protein modification ALB;SKP1 28096:[DB06728 DB01415] DB06728|Aniline KLK1;ALB;CYP2E1 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLC22A6 28097:[DB06728 DB06803] DB06728|Aniline KLK1;ALB;CYP2E1 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2C9 28098:[DB06728 DB06914] DB06728|Aniline KLK1;ALB;CYP2E1 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP2E1 28099:[DB06728 DB03937] DB06728|Aniline KLK1;ALB;CYP2E1 DB03937|Erythose-4-Phosphate kdsA;GPI common genes common pathways 28100:[DB06728 DB00175] DB06728|Aniline KLK1;ALB;CYP2E1 DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes common pathways GO:0045471| response to ethanol CYP2E1;HMGCR GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1B1;ABCB11;SLCO1B3;SLCO1A2 GO:0008202| steroid metabolic process CYP2C8;HMGCR;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLC22A6;SLC22A11;SLC22A7;SLCO1A2;SLCO1B1;SLC22A8;SLCO1B3 GO:0017144| drug metabolic process CYP2E1;CYP2C8 GO:0042493| response to drug CYP2E1;ABCB1;ABCC2;ABCG2 GO:0055114| oxidation-reduction process CYP2E1;HMGCR;CYP2C8 GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 28101:[DB06728 DB00940] DB06728|Aniline KLK1;ALB;CYP2E1 DB00940|Methantheline CHRM1;HRH2 common genes common pathways 28102:[DB06728 DB01837] DB06728|Aniline KLK1;ALB;CYP2E1 DB01837|O-acetyl-L-serine PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PTGS1 GO:0098869| ALB;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 28103:[DB06728 DB05943] DB06728|Aniline KLK1;ALB;CYP2E1 DB05943|Resatorvid CSF2RB;IL2RG common genes common pathways GO:0044267| cellular protein metabolic process ALB;CSF2RB 28104:[DB06728 DB09422] DB06728|Aniline KLK1;ALB;CYP2E1 DB09422|Soybean oil PPARA common genes common pathways 28105:[DB06728 DB00098] DB06728|Aniline KLK1;ALB;CYP2E1 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways GO:0006898| receptor-mediated endocytosis FCGR2B;ALB GO:0002576| platelet degranulation ITGB3;ALB 28106:[DB06728 DB03245] DB06728|Aniline KLK1;ALB;CYP2E1 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways GO:0055114| oxidation-reduction process GCDH;CYP2E1 28107:[DB06728 DB00302] DB06728|Aniline KLK1;ALB;CYP2E1 DB00302|Tranexamic acid PLG;SLC15A2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;PLG GO:0002576| platelet degranulation ALB;PLG GO:0006508| proteolysis KLK1;PLG 28108:[DB06728 DB00816] DB06728|Aniline KLK1;ALB;CYP2E1 DB00816|Orciprenaline ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 28109:[DB06728 DB01983] DB06728|Aniline KLK1;ALB;CYP2E1 DB01983|2(S)-Amino-6-Boronohexanoic Acid ARG1 common genes common pathways GO:0042493| response to drug ARG1;CYP2E1 28110:[DB06728 DB02548] DB06728|Aniline KLK1;ALB;CYP2E1 DB02548|D-glucitol 6-phosphate GPI common genes common pathways 28111:[DB06728 DB04185] DB06728|Aniline KLK1;ALB;CYP2E1 DB04185|Norvaline OTC;GATM common genes common pathways GO:0042493| response to drug CYP2E1;OTC 28112:[DB06728 DB00543] DB06728|Aniline KLK1;ALB;CYP2E1 DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0042493| response to drug HTR2C;HTR2B;SLC6A3;HTR1B;DRD2;ADRA1A;DRD3;SLC6A2;SLC6A4;GABRG3;DRD1;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0002576| platelet degranulation ORM1;ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0045471| response to ethanol CYP2E1;DRD3;SLC6A3;HTR3A;HTR1B;DRD2 28113:[DB06728 DB08962] DB06728|Aniline KLK1;ALB;CYP2E1 DB08962|Glibornuride CYP2C9 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 28114:[DB06728 DB03903] DB06728|Aniline KLK1;ALB;CYP2E1 DB03903|Tmr ACTA1 common genes common pathways 28115:[DB06728 DB00936] DB06728|Aniline KLK1;ALB;CYP2E1 DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;AKR1C1 GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0098869| PTGS2;PTGS1;ALB GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLC22A6;SLC22A10;SLC22A7;SLC22A11;SLC22A8 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;PTGS1;CYP2E1;AKR1C1;PTGS2 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug PTGS2;CYP2E1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1;AKR1C1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28116:[DB06728 DB01165] DB06728|Aniline KLK1;ALB;CYP2E1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug ABCC2;ABCC1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 28117:[DB06728 DB00671] DB06728|Aniline KLK1;ALB;CYP2E1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 28118:[DB06728 DB03410] DB06728|Aniline KLK1;ALB;CYP2E1 DB03410|4-hydroxycoumarin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28119:[DB06728 DB06685] DB06728|Aniline KLK1;ALB;CYP2E1 DB06685|Laquinimod CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 28120:[DB06728 DB05801] DB06728|Aniline KLK1;ALB;CYP2E1 DB05801|GTI 2040 RRM2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;RRM2 28121:[DB06728 DB01959] DB06728|Aniline KLK1;ALB;CYP2E1 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways 28122:[DB06728 DB01618] DB06728|Aniline KLK1;ALB;CYP2E1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug DRD2;CYP2E1;HTR2A 28123:[DB06728 DB08894] DB06728|Aniline KLK1;ALB;CYP2E1 DB08894|Peginesatide EPOR common genes common pathways 28124:[DB06728 DB07546] DB06728|Aniline KLK1;ALB;CYP2E1 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways 28125:[DB06728 DB05111] DB06728|Aniline KLK1;ALB;CYP2E1 DB05111|Fontolizumab IFNG common genes common pathways 28126:[DB06728 DB01023] DB06728|Aniline KLK1;ALB;CYP2E1 DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP3A5;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8;CYP2C9 GO:0002576| platelet degranulation CALM1;ALB GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A5;CYP2C9;CYP3A7;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C8;CYP2C9;CYP3A7;CYP3A4;CYP2E1 28127:[DB06728 DB00617] DB06728|Aniline KLK1;ALB;CYP2E1 DB00617|Paramethadione CACNA1I;CYP2E1;CYP3A4;CYP2C9;CYP2C8 common genes CYP2E1 common pathways GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2C9 GO:0010243| response to organic nitrogen CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8;CYP2C9 GO:0018910| benzene metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 28128:[DB06728 DB03600] DB06728|Aniline KLK1;ALB;CYP2E1 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006508| proteolysis KLK1;FURIN GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process FURIN;ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug CYP2E1;PPARG GO:0043687| post-translational protein modification ALB 28129:[DB06728 DB01029] DB06728|Aniline KLK1;ALB;CYP2E1 DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0042493| response to drug JUN;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;PTGS1;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;JUN GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP2E1;CYP3A4 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A3;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;PTGS1;CYP2C9;CYP2C8 28130:[DB06728 DB01436] DB06728|Aniline KLK1;ALB;CYP2E1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;ALB GO:0055114| oxidation-reduction process CYP2E1;CYP27B1 28131:[DB06728 DB00681] DB06728|Aniline KLK1;ALB;CYP2E1 DB00681|Amphotericin B CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28132:[DB06728 DB00866] DB06728|Aniline KLK1;ALB;CYP2E1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 28133:[DB06728 DB03975] DB06728|Aniline KLK1;ALB;CYP2E1 DB03975|Mercuribenzoic Acid CA2 common genes common pathways 28134:[DB06728 DB09069] DB06728|Aniline KLK1;ALB;CYP2E1 DB09069|Trimetazidine ACAA1 common genes common pathways 28135:[DB06728 DB08256] DB06728|Aniline KLK1;ALB;CYP2E1 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;EPHX2 GO:0006805| xenobiotic metabolic process EPHX2;CYP2E1 28136:[DB06728 DB02563] DB06728|Aniline KLK1;ALB;CYP2E1 DB02563|Hexanoyl-CoA ECHS1 common genes common pathways 28137:[DB06728 DB06233] DB06728|Aniline KLK1;ALB;CYP2E1 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0009267| cellular response to starvation MTOR;ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28138:[DB06728 DB07830] DB06728|Aniline KLK1;ALB;CYP2E1 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28139:[DB06728 DB00843] DB06728|Aniline KLK1;ALB;CYP2E1 DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0042493| response to drug CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP3A4;CYP2E1 28140:[DB06728 DB02087] DB06728|Aniline KLK1;ALB;CYP2E1 DB02087|3,5-Difluorobenzenesulfonamide CA2 common genes common pathways 28141:[DB06728 DB00987] DB06728|Aniline KLK1;ALB;CYP2E1 DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol POLB;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 28142:[DB06728 DB11785] DB06728|Aniline KLK1;ALB;CYP2E1 DB11785|Anisodamine CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 28143:[DB06728 DB12450] DB06728|Aniline KLK1;ALB;CYP2E1 DB12450|Propyl Gallate ESR1 common genes common pathways 28144:[DB06728 DB05258] DB06728|Aniline KLK1;ALB;CYP2E1 DB05258|Natural alpha interferon IFNAR1 common genes common pathways 28145:[DB06728 DB07233] DB06728|Aniline KLK1;ALB;CYP2E1 DB07233|N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan ADAM17 common genes common pathways GO:0006508| proteolysis KLK1;ADAM17 GO:0042493| response to drug ADAM17;CYP2E1 28146:[DB06728 DB08864] DB06728|Aniline KLK1;ALB;CYP2E1 DB08864|Rilpivirine pol;NR1I2;CYP3A4;CYP2C19;CYP2B6;CYP2D6;ALB;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes ALB common pathways GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;NR1I2;CYP2B6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2B6;NR1I2 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2B6;CYP2C19;CYP2D6 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C19;CYP2E1 GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 GO:0055114| oxidation-reduction process CYP2B6;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB 28147:[DB06728 DB08936] DB06728|Aniline KLK1;ALB;CYP2E1 DB08936|Chlorcyclizine HRH1 common genes common pathways 28148:[DB06728 DB04608] DB06728|Aniline KLK1;ALB;CYP2E1 DB04608|9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE WEE1 common genes common pathways 28149:[DB06728 DB09160] DB06728|Aniline KLK1;ALB;CYP2E1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 28150:[DB06728 DB12872] DB06728|Aniline KLK1;ALB;CYP2E1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0002576| platelet degranulation ALB;F8 GO:0055114| oxidation-reduction process F8;CYP2E1 GO:0042493| response to drug CYP2E1;COL1A1 GO:0006508| proteolysis KLK1;ADAMTS13 28151:[DB06728 DB09371] DB06728|Aniline KLK1;ALB;CYP2E1 DB09371|Norethynodrel ESR1;AR;SHBG;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 28152:[DB06728 DB00135] DB06728|Aniline KLK1;ALB;CYP2E1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC16A2;ALB GO:0055114| oxidation-reduction process TH;CYP2E1 GO:0042493| response to drug TH;CYP2E1 GO:0045471| response to ethanol TH;CYP2E1 28153:[DB06728 DB02340] DB06728|Aniline KLK1;ALB;CYP2E1 DB02340|N-Acetyl-Serine F13A1 common genes common pathways GO:0002576| platelet degranulation F13A1;ALB 28154:[DB06728 DB07521] DB06728|Aniline KLK1;ALB;CYP2E1 DB07521|6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 28155:[DB06728 DB06477] DB06728|Aniline KLK1;ALB;CYP2E1 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 GO:0042493| response to drug DRD2;DRD3;CYP2E1 28156:[DB06728 DB08877] DB06728|Aniline KLK1;ALB;CYP2E1 DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 28157:[DB06728 DB02483] DB06728|Aniline KLK1;ALB;CYP2E1 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;LDHA GO:0042493| response to drug LDHA;CYP2E1 28158:[DB06728 DB07092] DB06728|Aniline KLK1;ALB;CYP2E1 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28159:[DB06728 DB11641] DB06728|Aniline KLK1;ALB;CYP2E1 DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;ORM1;ORM2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 28160:[DB06728 DB00654] DB06728|Aniline KLK1;ALB;CYP2E1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGFR;ALB GO:0015721| bile acid and bile salt transport SLCO2B1;ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1 28161:[DB06728 DB01211] DB06728|Aniline KLK1;ALB;CYP2E1 DB01211|Clarithromycin rplJ;KCNH2;SLCO1B1;SLCO1B3;CYP3A4;CYP3A5;CYP2C19;CYP3A7;SLC22A7;ABCB1;ABCB11 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP3A4;CYP2E1;CYP3A7 GO:0055114| oxidation-reduction process CYP2C19;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1B1;SLCO1B3;ALB GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP2C19;CYP3A5 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;SLC22A7;ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19 28162:[DB06728 DB07907] DB06728|Aniline KLK1;ALB;CYP2E1 DB07907|(2S)-2-HYDROXYOCTANOIC ACID HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HAO1 28163:[DB06728 DB02848] DB06728|Aniline KLK1;ALB;CYP2E1 DB02848|{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol FBP1 common genes common pathways 28164:[DB06728 DB04363] DB06728|Aniline KLK1;ALB;CYP2E1 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways GO:0055114| oxidation-reduction process BLVRB;CYP2E1 28165:[DB06728 DB09269] DB06728|Aniline KLK1;ALB;CYP2E1 DB09269|Phenylacetic acid CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 28166:[DB06728 DB07255] DB06728|Aniline KLK1;ALB;CYP2E1 DB07255|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3-MORPHOLIN-4-YLPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways 28167:[DB06728 DB00292] DB06728|Aniline KLK1;ALB;CYP2E1 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0008202| steroid metabolic process CYP11B1;CYP11B2;CYP2E1 GO:0055114| oxidation-reduction process CYP19A1;CYP2E1;CYP11B2;CYP11B1 GO:0042493| response to drug GABRG3;CYP2E1 28168:[DB06728 DB01218] DB06728|Aniline KLK1;ALB;CYP2E1 DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C8;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 28169:[DB06728 DB00263] DB06728|Aniline KLK1;ALB;CYP2E1 DB00263|Sulfisoxazole CYP2C9 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 28170:[DB06728 DB01099] DB06728|Aniline KLK1;ALB;CYP2E1 DB01099|Flucytosine DNMT1 common genes common pathways 28171:[DB06728 DB07458] DB06728|Aniline KLK1;ALB;CYP2E1 DB07458|3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione PRKACA common genes common pathways 28172:[DB06728 DB02857] DB06728|Aniline KLK1;ALB;CYP2E1 DB02857|Guanosine PNP common genes common pathways GO:0042493| response to drug PNP;CYP2E1 28173:[DB06728 DB01204] DB06728|Aniline KLK1;ALB;CYP2E1 DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes CYP2E1 common pathways GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2E1;CYP3A4 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1B1;CYP2E1;CYP3A4 GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1B1 GO:0042493| response to drug CYP2E1;ABCC1;ABCG2;ABCB1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1B1 28174:[DB06728 DB06267] DB06728|Aniline KLK1;ALB;CYP2E1 DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5 GO:0055114| oxidation-reduction process CYP3A5;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 28175:[DB06728 DB06660] DB06728|Aniline KLK1;ALB;CYP2E1 DB06660|Saredutant TACR2 common genes common pathways 28176:[DB06728 DB07129] DB06728|Aniline KLK1;ALB;CYP2E1 DB07129|(2R)-1-(2,6-dimethylphenoxy)propan-2-amine PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 28177:[DB06728 DB09090] DB06728|Aniline KLK1;ALB;CYP2E1 DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 28178:[DB06728 DB12836] DB06728|Aniline KLK1;ALB;CYP2E1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28179:[DB06728 DB06281] DB06728|Aniline KLK1;ALB;CYP2E1 DB06281|Torcetrapib CETP;CYP11B2 common genes common pathways GO:0034375| high-density lipoprotein particle remodeling CETP;ALB GO:0006641| triglyceride metabolic process CYP2E1;CETP GO:0008202| steroid metabolic process CETP;CYP11B2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP11B2 28180:[DB06728 DB03064] DB06728|Aniline KLK1;ALB;CYP2E1 DB03064|3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline HAO1 common genes common pathways GO:0055114| oxidation-reduction process HAO1;CYP2E1 28181:[DB06728 DB00139] DB06728|Aniline KLK1;ALB;CYP2E1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;HSD17B6 GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 GO:0042493| response to drug CYP2E1;OXCT1 GO:0055114| oxidation-reduction process SDHC;BBOX1;P3H1;ALDH5A1;P4HA1;TMLHE;CYP2E1;P3H3;SDHA;SDHD;P4HA2;P3H2;PLOD1;SDHB;PLOD3;HSD17B6;ASPH GO:0045471| response to ethanol OXCT1;CYP2E1 28182:[DB06728 DB02110] DB06728|Aniline KLK1;ALB;CYP2E1 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;CYCS;CYP2E1 GO:0098869| ALB;PTGS1 28183:[DB06728 DB01854] DB06728|Aniline KLK1;ALB;CYP2E1 DB01854|5-Bromonicotinamide ART1 common genes common pathways 28184:[DB06728 DB06156] DB06728|Aniline KLK1;ALB;CYP2E1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A3;SLC6A2;SLC6A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;SLC6A3 28185:[DB06728 DB09016] DB06728|Aniline KLK1;ALB;CYP2E1 DB09016|Butriptyline SLC6A4;HRH1;HTR2A common genes common pathways GO:0042493| response to drug CYP2E1;HTR2A;SLC6A4 28186:[DB06728 DB01430] DB06728|Aniline KLK1;ALB;CYP2E1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 28187:[DB06728 DB04234] DB06728|Aniline KLK1;ALB;CYP2E1 DB04234|N2-({[(4-Bromophenyl)Methyl]Oxy}Carbonyl)-N1-[(1s)-1-Formylpentyl]-L-Leucinamide CTSK common genes common pathways GO:0006508| proteolysis KLK1;CTSK 28188:[DB06728 DB06701] DB06728|Aniline KLK1;ALB;CYP2E1 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A4;CYP2E1;SLC6A3;SLC6A2 GO:0045471| response to ethanol SLC6A3;CYP2E1 28189:[DB06728 DB00736] DB06728|Aniline KLK1;ALB;CYP2E1 DB00736|Esomeprazole ATP4A;CYP2C19;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 28190:[DB06728 DB13164] DB06728|Aniline KLK1;ALB;CYP2E1 DB13164|Olmutinib EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;ALB 28191:[DB06728 DB01198] DB06728|Aniline KLK1;ALB;CYP2E1 DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes CYP2E1 common pathways GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug TSPO;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP2E1;CYP3A4;PTGS1 GO:0010243| response to organic nitrogen CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP2E1;CYP3A4;TSPO GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4 GO:0010193| response to ozone CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4;PTGS1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 28192:[DB06728 DB09334] DB06728|Aniline KLK1;ALB;CYP2E1 DB09334|Seractide acetate MC2R common genes common pathways 28193:[DB06728 DB03752] DB06728|Aniline KLK1;ALB;CYP2E1 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process PTGS1;CYP2E1 28194:[DB06728 DB04017] DB06728|Aniline KLK1;ALB;CYP2E1 DB04017|Clorgiline MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 28195:[DB06728 DB08291] DB06728|Aniline KLK1;ALB;CYP2E1 DB08291|N-(3-AMINOPROPYL)-2-NITROBENZENAMINE KAT2B common genes common pathways 28196:[DB06728 DB00854] DB06728|Aniline KLK1;ALB;CYP2E1 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1 28197:[DB06728 DB03150] DB06728|Aniline KLK1;ALB;CYP2E1 DB03150|2',3'-Dideoxythymidine-5'-Monophosphate DTYMK common genes common pathways 28198:[DB06728 DB04614] DB06728|Aniline KLK1;ALB;CYP2E1 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways 28199:[DB06728 DB08005] DB06728|Aniline KLK1;ALB;CYP2E1 DB08005|4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide MAPK10 common genes common pathways 28200:[DB06728 DB00493] DB06728|Aniline KLK1;ALB;CYP2E1 DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes ALB common pathways GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A11;SLC22A7;SLC22A8 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28201:[DB06728 DB06848] DB06728|Aniline KLK1;ALB;CYP2E1 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways GO:0006508| proteolysis TPSAB1;KLK1 28202:[DB06728 DB08695] DB06728|Aniline KLK1;ALB;CYP2E1 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways 28203:[DB06728 DB14050] DB06728|Aniline KLK1;ALB;CYP2E1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0042493| response to drug TRPA1;CYP2E1 GO:0010243| response to organic nitrogen TRPV1;CYP2E1 28204:[DB06728 DB01245] DB06728|Aniline KLK1;ALB;CYP2E1 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0045471| response to ethanol CHRNB2;CYP2E1 GO:0042493| response to drug CYP2E1;BCHE 28205:[DB06728 DB00622] DB06728|Aniline KLK1;ALB;CYP2E1 DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes CYP2E1 common pathways GO:0002576| platelet degranulation CALM1;ALB GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C19;CYP2C8;CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1;ADRA1A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP2B6 GO:0010243| response to organic nitrogen CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP3A5;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C8;CYP2B6 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1B1;ALB GO:0010193| response to ozone CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0045471| response to ethanol CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 28206:[DB06728 DB07145] DB06728|Aniline KLK1;ALB;CYP2E1 DB07145|(2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE ADAM17 common genes common pathways GO:0042493| response to drug CYP2E1;ADAM17 GO:0006508| proteolysis ADAM17;KLK1 28207:[DB06728 DB05785] DB06728|Aniline KLK1;ALB;CYP2E1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0045471| response to ethanol RARA;CYP2E1 GO:0043066| negative regulation of apoptotic process RARA;RARG;JUN;RARB;ALB GO:0042493| response to drug CYP2E1;JUN 28208:[DB06728 DB02580] DB06728|Aniline KLK1;ALB;CYP2E1 DB02580|Pentaglyme PFN2;gpmA;purA common genes common pathways 28209:[DB06728 DB08617] DB06728|Aniline KLK1;ALB;CYP2E1 DB08617|4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE YARS common genes common pathways 28210:[DB06728 DB00119] DB06728|Aniline KLK1;ALB;CYP2E1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0045471| response to ethanol ABAT;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PDHB GO:0042493| response to drug ABAT;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO2A1;ALB;SLC16A2 28211:[DB06728 DB00212] DB06728|Aniline KLK1;ALB;CYP2E1 DB00212|Remikiren REN common genes common pathways GO:0006508| proteolysis REN;KLK1 GO:0042493| response to drug CYP2E1;REN 28212:[DB06728 DB02623] DB06728|Aniline KLK1;ALB;CYP2E1 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways 28213:[DB06728 DB01805] DB06728|Aniline KLK1;ALB;CYP2E1 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways GO:0006508| proteolysis PRSS1;PRSS2;KLK1 28214:[DB06728 DB01232] DB06728|Aniline KLK1;ALB;CYP2E1 DB01232|Saquinavir pol;CYP3A7;CYP3A5;CYP3A4;CYP11A1;CYP2C8;CYP2D6;ORM1;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;ABCC1;ABCC2;SLCO2B1;ABCB11 common genes ALB common pathways GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1A2;ABCB11;SLCO1B1 GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1B1;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP11A1;CYP3A7;CYP3A5;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A5;CYP11A1;CYP2E1;CYP3A4;CYP3A7 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;ABCG2;ABCC2;ABCB1;ABCC1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;ORM1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP2C8;CYP2D6;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 28215:[DB06728 DB02185] DB06728|Aniline KLK1;ALB;CYP2E1 DB02185|2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One LCTL common genes common pathways 28216:[DB06728 DB08187] DB06728|Aniline KLK1;ALB;CYP2E1 DB08187|METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 28217:[DB06728 DB11201] DB06728|Aniline KLK1;ALB;CYP2E1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0098869| ALB;PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 28218:[DB06728 DB00370] DB06728|Aniline KLK1;ALB;CYP2E1 DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C9;CYP2D6;CYP2C8 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1;CYP1A2 GO:0042493| response to drug HTR2A;CYP2E1;CYP1A2;DRD1;SLC6A4;DRD3;SLC6A2;SLC6A3;HTR2B;HTR2C;ADRA1A;DRD2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C8;CYP2C9 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0045471| response to ethanol CYP2E1;OPRK1;SLC6A3;HTR3A;DRD2;DRD3 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C9;CYP2D6;CYP2C8 28219:[DB06728 DB02418] DB06728|Aniline KLK1;ALB;CYP2E1 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways 28220:[DB06728 DB11626] DB06728|Aniline KLK1;ALB;CYP2E1 DB11626|Tasonermin TNFRSF1A;TNFRSF1B common genes common pathways 28221:[DB06728 DB01118] DB06728|Aniline KLK1;ALB;CYP2E1 DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP1A1;CYP2C9 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2A6;CYP2E1;CYP2C19;CYP2C8;CYP1A1;CYP2C9 GO:0042493| response to drug PPARG;CYP1A1;ABCB1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2A6;CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C9;CYP1A1;CYP2C19;CYP2C8;CYP2D6;CYP3A5 28222:[DB06728 DB04510] DB06728|Aniline KLK1;ALB;CYP2E1 DB04510|3-phospho-D-glyceric acid PGK1;PGAM2;TPI1 common genes common pathways 28223:[DB06728 DB00392] DB06728|Aniline KLK1;ALB;CYP2E1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN3A GO:0042493| response to drug CYP2E1;BCHE 28224:[DB06728 DB08632] DB06728|Aniline KLK1;ALB;CYP2E1 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBA1;HBB GO:0098869| HBA1;HBB;ALB 28225:[DB06728 DB09559] DB06728|Aniline KLK1;ALB;CYP2E1 DB09559|Necitumumab EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 28226:[DB06728 DB00775] DB06728|Aniline KLK1;ALB;CYP2E1 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways GO:0002576| platelet degranulation ALB;ITGB3;ITGA2B 28227:[DB06728 DB00768] DB06728|Aniline KLK1;ALB;CYP2E1 DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process S100A12;CYP3A4;CYP2E1 28228:[DB06728 DB00483] DB06728|Aniline KLK1;ALB;CYP2E1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways 28229:[DB06728 DB07297] DB06728|Aniline KLK1;ALB;CYP2E1 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways GO:0042493| response to drug LCK;CYP2E1 28230:[DB06728 DB00802] DB06728|Aniline KLK1;ALB;CYP2E1 DB00802|Alfentanil OPRM1;CYP3A4;CYP3A7;CYP3A5;ORM1;ALB;ABCB1 common genes ALB common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0002576| platelet degranulation ALB;ORM1 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0045471| response to ethanol OPRM1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB 28231:[DB06728 DB03680] DB06728|Aniline KLK1;ALB;CYP2E1 DB03680|Tartronate ME2;ME3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ME3;ME2 28232:[DB06728 DB00300] DB06728|Aniline KLK1;ALB;CYP2E1 DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A8 GO:0043066| negative regulation of apoptotic process NME2;ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0042493| response to drug ABCC4;NME1;AK4;CYP2E1;ABCB1;ABCC2 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 28233:[DB06728 DB06957] DB06728|Aniline KLK1;ALB;CYP2E1 DB06957|4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 28234:[DB06728 DB00416] DB06728|Aniline KLK1;ALB;CYP2E1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways 28235:[DB06728 DB01036] DB06728|Aniline KLK1;ALB;CYP2E1 DB01036|Tolterodine CHRM3;CHRM2;CHRM5;CHRM1;CHRM4;CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 28236:[DB06728 DB01914] DB06728|Aniline KLK1;ALB;CYP2E1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC2A4 28237:[DB06728 DB02994] DB06728|Aniline KLK1;ALB;CYP2E1 DB02994|Cacodylic acid NOS3;AKR1B1;GNAT1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;NOS3;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 28238:[DB06728 DB04005] DB06728|Aniline KLK1;ALB;CYP2E1 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways 28239:[DB06728 DB03376] DB06728|Aniline KLK1;ALB;CYP2E1 DB03376|'5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 28240:[DB06728 DB06506] DB06728|Aniline KLK1;ALB;CYP2E1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 28241:[DB06728 DB00063] DB06728|Aniline KLK1;ALB;CYP2E1 DB00063|Eptifibatide ITGB3 common genes common pathways GO:0002576| platelet degranulation ALB;ITGB3 28242:[DB06728 DB04751] DB06728|Aniline KLK1;ALB;CYP2E1 DB04751|Purvalanol A SRC;CSNK1G3;RPS6KA1 common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB;RPS6KA1 GO:0042493| response to drug SRC;CYP2E1 28243:[DB06728 DB04917] DB06728|Aniline KLK1;ALB;CYP2E1 DB04917|Renzapride HTR3A;HTR4 common genes common pathways GO:0045471| response to ethanol HTR3A;CYP2E1 28244:[DB06728 DB00149] DB06728|Aniline KLK1;ALB;CYP2E1 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC16A2;ALB 28245:[DB06728 DB08251] DB06728|Aniline KLK1;ALB;CYP2E1 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways GO:0042493| response to drug CASP3;CYP2E1 GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0006508| proteolysis CASP3;KLK1 28246:[DB06728 DB00960] DB06728|Aniline KLK1;ALB;CYP2E1 DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug HTR1B;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0045471| response to ethanol HTR1B;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 28247:[DB06728 DB03575] DB06728|Aniline KLK1;ALB;CYP2E1 DB03575|Phencyclidine GRIN3A;SIGMAR1;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0017144| drug metabolic process CYP2B6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2B6 GO:0045471| response to ethanol GRIN3A;CYP2E1 28248:[DB06728 DB01917] DB06728|Aniline KLK1;ALB;CYP2E1 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 28249:[DB06728 DB06861] DB06728|Aniline KLK1;ALB;CYP2E1 DB06861|6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 28250:[DB06728 DB14568] DB06728|Aniline KLK1;ALB;CYP2E1 DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2B6;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2B6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2B6;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2B6;CYP2C8 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2C9;IDH1;CYP2B6 28251:[DB06728 DB03256] DB06728|Aniline KLK1;ALB;CYP2E1 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways 28252:[DB06728 DB08486] DB06728|Aniline KLK1;ALB;CYP2E1 DB08486|Efaproxiral HBA1;HBB common genes common pathways GO:0098869| ALB;HBA1;HBB GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 28253:[DB06728 DB08302] DB06728|Aniline KLK1;ALB;CYP2E1 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 28254:[DB06728 DB00943] DB06728|Aniline KLK1;ALB;CYP2E1 DB00943|Zalcitabine pol;DCK;ALB;SLC22A6;SLC22A7;SLC29A1;SLC29A2 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A7;ALB;SLC22A6 GO:0098869| ALB 28255:[DB06728 DB07842] DB06728|Aniline KLK1;ALB;CYP2E1 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 28256:[DB06728 DB09273] DB06728|Aniline KLK1;ALB;CYP2E1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0042493| response to drug CYP2E1;CYP1A2;ADORA2A GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 28257:[DB06728 DB05308] DB06728|Aniline KLK1;ALB;CYP2E1 DB05308|ANX-510 TYMS common genes common pathways GO:0045471| response to ethanol TYMS;CYP2E1 GO:0042493| response to drug CYP2E1;TYMS 28258:[DB06728 DB04764] DB06728|Aniline KLK1;ALB;CYP2E1 DB04764|[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE TPSB2 common genes common pathways GO:0006508| proteolysis TPSB2;KLK1 28259:[DB06728 DB08289] DB06728|Aniline KLK1;ALB;CYP2E1 DB08289|N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM-N-OXIDE IGKC common genes common pathways GO:0006508| proteolysis IGKC;KLK1 GO:0001895| retina homeostasis IGKC;ALB GO:0006898| receptor-mediated endocytosis ALB;IGKC 28260:[DB06728 DB00290] DB06728|Aniline KLK1;ALB;CYP2E1 DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0042493| response to drug CYP2E1;BLMH GO:0006508| proteolysis BLMH;KLK1 28261:[DB06728 DB00732] DB06728|Aniline KLK1;ALB;CYP2E1 DB00732|Atracurium besylate CHRNA2 common genes common pathways 28262:[DB06728 DB07302] DB06728|Aniline KLK1;ALB;CYP2E1 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 28263:[DB06728 DB02166] DB06728|Aniline KLK1;ALB;CYP2E1 DB02166|Propidium ACHE common genes common pathways 28264:[DB06728 DB14597] DB06728|Aniline KLK1;ALB;CYP2E1 DB14597|Lanadelumab KLKB1 common genes common pathways GO:0006508| proteolysis KLKB1;KLK1 28265:[DB06728 DB07047] DB06728|Aniline KLK1;ALB;CYP2E1 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 28266:[DB06728 DB08897] DB06728|Aniline KLK1;ALB;CYP2E1 DB08897|Aclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 28267:[DB06728 DB00945] DB06728|Aniline KLK1;ALB;CYP2E1 DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process NFKBIA;ALB;PRKAA1;PRKAA2;RPS6KA3;HSPA5;TP53;NFKB1;IKBKB;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19;CYP2E1 GO:0002576| platelet degranulation ALB GO:0010243| response to organic nitrogen TP53;CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2;TP53;ABCB1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP2C19;PTGS2;CYP2E1;AKR1C1;PTGS1 GO:0098869| PTGS1;PTGS2;ALB GO:0017144| drug metabolic process CYP2E1;CYP2C9;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP2E1;PRKAA2;CYP2C9;CYP2C8;CYP2C19;PRKAA1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A7 GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB;AKR1C1 GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP2E1;AKR1C1;PTGS1;CYP2C9;CYP2C19;CYP2C8 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0045471| response to ethanol CYP2E1;TP53 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 28268:[DB06728 DB09517] DB06728|Aniline KLK1;ALB;CYP2E1 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways GO:0098869| HBB;HBA1;ALB GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 28269:[DB06728 DB07144] DB06728|Aniline KLK1;ALB;CYP2E1 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP2E1 28270:[DB06728 DB06739] DB06728|Aniline KLK1;ALB;CYP2E1 DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP2A6;CYP2E1;CYP3A4 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2E1;UGT1A9;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0042493| response to drug TBXA2R;CYP2E1 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2E1;PTGS1;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0045471| response to ethanol TBXA2R;CYP2E1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP2C19;CYP2C8;UGT1A9;CYP2C9;CYP2B6 28271:[DB06728 DB00296] DB06728|Aniline KLK1;ALB;CYP2E1 DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2B6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP2B6 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2B6 GO:0017144| drug metabolic process CYP2B6;CYP2E1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6 28272:[DB06728 DB04396] DB06728|Aniline KLK1;ALB;CYP2E1 DB04396|Thiodigalactoside NCAN;LGALS1 common genes common pathways GO:0042493| response to drug LGALS1;CYP2E1 GO:0043687| post-translational protein modification LGALS1;ALB GO:0044267| cellular protein metabolic process ALB;LGALS1 28273:[DB06728 DB07670] DB06728|Aniline KLK1;ALB;CYP2E1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C18 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C18 GO:0055114| oxidation-reduction process CYP2C18;CYP2E1 28274:[DB06728 DB07643] DB06728|Aniline KLK1;ALB;CYP2E1 DB07643|5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways GO:0043069| negative regulation of programmed cell death DCPS;ALB 28275:[DB06728 DB08915] DB06728|Aniline KLK1;ALB;CYP2E1 DB08915|Aleglitazar PPARA;PPARG;NCOA1 common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;NCOA1 28276:[DB06728 DB01087] DB06728|Aniline KLK1;ALB;CYP2E1 DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;NQO2;CYP2D6;CYP1B1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;NQO2;CYP2D6;CYP1B1;CYP2E1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP1B1;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1B1;CYP2D6;CYP1A1 28277:[DB06728 DB06247] DB06728|Aniline KLK1;ALB;CYP2E1 DB06247|CX516 GRIA1 common genes common pathways 28278:[DB06728 DB07740] DB06728|Aniline KLK1;ALB;CYP2E1 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways GO:0008202| steroid metabolic process HMGCS1;CYP2E1 GO:0042493| response to drug HMGCS1;CYP2E1 28279:[DB06728 DB02404] DB06728|Aniline KLK1;ALB;CYP2E1 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways 28280:[DB06728 DB11753] DB06728|Aniline KLK1;ALB;CYP2E1 DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1B3;SLCO1B1;SLCO1A2 GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO2A1;ALB;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C8;CYP2C9;CYP2B6 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCB1;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C19;CYP2C8;CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19 28281:[DB06728 DB04469] DB06728|Aniline KLK1;ALB;CYP2E1 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 28282:[DB06728 DB01124] DB06728|Aniline KLK1;ALB;CYP2E1 DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8;CYP2E1;CYP2C18 GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP2E1;CYP2C18;CYP2C9;CYP2C8;CYP2C19 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCC8;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP2C9;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A6;ALB;SLCO2B1 GO:0017144| drug metabolic process CYP2E1;CYP2C8;CYP2C19;CYP2C9 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO2B1;ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C18;CYP2E1;CYP2C8;CYP2C19;CYP2C9 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 28283:[DB06728 DB00595] DB06728|Aniline KLK1;ALB;CYP2E1 DB00595|Oxytetracycline rpsI;rpsD;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A7;SLC22A11;SLC22A8 28284:[DB06728 DB06530] DB06728|Aniline KLK1;ALB;CYP2E1 DB06530|Resiquimod TLR7;TLR8 common genes common pathways 28285:[DB06728 DB06607] DB06728|Aniline KLK1;ALB;CYP2E1 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FCGR1A 28286:[DB06728 DB00997] DB06728|Aniline KLK1;ALB;CYP2E1 DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ABCC3;ALB;ABCB11 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;AKR1C3;CYP2D6;CYP1B1;CYP2B6 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB;AKR1C3 GO:0098869| ALB GO:0017144| drug metabolic process CBR1;CYP3A4;CYP2E1;CYP2D6;CYP2B6 GO:0042493| response to drug ABCC2;ABCG2;ABCB1;POR;ABCC1;ABCC6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;NDUFS3;XDH;AKR1C3;CBR1;NDUFS7;NOS1;NQO1;CYP2B6;AKR1A1;NOS2;NDUFS2;NOS3;CYP2D6;POR;CYP1B1;CBR3 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process NQO1;ALB;POR GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2B6;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0045471| response to ethanol NQO1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6;POR;CYP1B1;CBR3;CYP2B6;NQO1 28287:[DB06728 DB08687] DB06728|Aniline KLK1;ALB;CYP2E1 DB08687|FG-2216 EGLN1;HIF1A common genes common pathways GO:0043687| post-translational protein modification HIF1A;ALB GO:0055114| oxidation-reduction process CYP2E1;EGLN1 GO:0043066| negative regulation of apoptotic process HIF1A;ALB 28288:[DB06728 DB00122] DB06728|Aniline KLK1;ALB;CYP2E1 DB00122|Choline PCYT1B;ACHE;PCYT1A;PLD2;BCHE;PLD1;PHOSPHO1;CHRNA7;CEPT1;CHKB;CHAT;CHKA;CHDH;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC44A1;SLC44A4;SLC44A2;SLC44A3;SLC5A7 common genes common pathways GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 GO:0042493| response to drug BCHE;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CHDH 28289:[DB06728 DB04801] DB06728|Aniline KLK1;ALB;CYP2E1 DB04801|cis-Vaccenic acid PPARD common genes common pathways GO:0043066| negative regulation of apoptotic process PPARD;ALB 28290:[DB06728 DB05391] DB06728|Aniline KLK1;ALB;CYP2E1 DB05391|liposomal prostaglandin E1 GP1BA common genes common pathways 28291:[DB06728 DB00266] DB06728|Aniline KLK1;ALB;CYP2E1 DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes ALB common pathways GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0045471| response to ethanol NQO1;CYP2E1 GO:0006805| xenobiotic metabolic process NQO1;CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;VKORC1;CYP2C9 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CRYZ;NQO1;CYP2C9;CYP2E1;VKORC1 28292:[DB06728 DB08192] DB06728|Aniline KLK1;ALB;CYP2E1 DB08192|2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE SRC common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC GO:0042493| response to drug CYP2E1;SRC 28293:[DB06728 DB09421] DB06728|Aniline KLK1;ALB;CYP2E1 DB09421|Protirelin TRHR common genes common pathways 28294:[DB06728 DB07652] DB06728|Aniline KLK1;ALB;CYP2E1 DB07652|1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE POLK;rnhA common genes common pathways 28295:[DB06728 DB08561] DB06728|Aniline KLK1;ALB;CYP2E1 DB08561|BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE MMP13 common genes common pathways GO:0044267| cellular protein metabolic process MMP13;ALB GO:0006508| proteolysis KLK1;MMP13 28296:[DB06728 DB00046] DB06728|Aniline KLK1;ALB;CYP2E1 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process IGF1R;ALB 28297:[DB06728 DB13783] DB06728|Aniline KLK1;ALB;CYP2E1 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0042493| response to drug CYP2E1;PTGS2;ABCC1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS2;PTGS1 GO:0008202| steroid metabolic process CYP2E1;UGT2B7 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 28298:[DB06728 DB00800] DB06728|Aniline KLK1;ALB;CYP2E1 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0042493| response to drug CYP2E1;DRD1;ADRA1A 28299:[DB06728 DB07229] DB06728|Aniline KLK1;ALB;CYP2E1 DB07229|3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-5-METHOXY-1,1'-BIPHENYL-2-OLATE PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 28300:[DB06728 DB05676] DB06728|Aniline KLK1;ALB;CYP2E1 DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;IL2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;NOS3 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;IL2 28301:[DB06728 DB07282] DB06728|Aniline KLK1;ALB;CYP2E1 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 28302:[DB06728 DB02427] DB06728|Aniline KLK1;ALB;CYP2E1 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP2E1 28303:[DB06728 DB06694] DB06728|Aniline KLK1;ALB;CYP2E1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 28304:[DB06728 DB05289] DB06728|Aniline KLK1;ALB;CYP2E1 DB05289|Tarenflurbil IKBKG common genes common pathways 28305:[DB06728 DB00168] DB06728|Aniline KLK1;ALB;CYP2E1 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;TRPV1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A11;SLC22A8 28306:[DB06728 DB07873] DB06728|Aniline KLK1;ALB;CYP2E1 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways 28307:[DB06728 DB12307] DB06728|Aniline KLK1;ALB;CYP2E1 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP2E1;CYP3A7;CYP3A43 GO:0043066| negative regulation of apoptotic process HGF;ALB;KDR GO:0002576| platelet degranulation HGF;ALB GO:0006508| proteolysis HGF;KLK1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 28308:[DB06728 DB11587] DB06728|Aniline KLK1;ALB;CYP2E1 DB11587|Etafedrine ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 28309:[DB06728 DB05262] DB06728|Aniline KLK1;ALB;CYP2E1 DB05262|Oxypurinol XDH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;XDH 28310:[DB06728 DB12436] DB06728|Aniline KLK1;ALB;CYP2E1 DB12436|Vofopitant TACR1 common genes common pathways GO:0010193| response to ozone TACR1;CYP2E1 GO:0045471| response to ethanol TACR1;CYP2E1 28311:[DB06728 DB06920] DB06728|Aniline KLK1;ALB;CYP2E1 DB06920|Eribaxaban F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 28312:[DB06728 DB06953] DB06728|Aniline KLK1;ALB;CYP2E1 DB06953|2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE FNTA;FNTB common genes common pathways 28313:[DB06728 DB04105] DB06728|Aniline KLK1;ALB;CYP2E1 DB04105|N-Heptylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;CYP2E1 28314:[DB06728 DB05407] DB06728|Aniline KLK1;ALB;CYP2E1 DB05407|TBC-3711 EDN1 common genes common pathways GO:0042493| response to drug CYP2E1;EDN1 GO:0010193| response to ozone EDN1;CYP2E1 28315:[DB06728 DB12555] DB06728|Aniline KLK1;ALB;CYP2E1 DB12555|Nelotanserin HTR2A common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1 28316:[DB06728 DB06469] DB06728|Aniline KLK1;ALB;CYP2E1 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0010243| response to organic nitrogen FLT3;CYP2E1 28317:[DB06728 DB06741] DB06728|Aniline KLK1;ALB;CYP2E1 DB06741|Gavestinel GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;UGT1A1;UGT1A3;UGT1A9;UGT2B4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;UGT2B4;UGT1A9 GO:0045471| response to ethanol GRIN2A;GRIN1;GRIN2B;CYP2E1;UGT1A1;GRIN3A GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0042493| response to drug UGT1A1;GRIN2A;CYP2E1 GO:0017144| drug metabolic process CYP2E1;UGT1A3;UGT1A1;UGT1A9 GO:0008202| steroid metabolic process UGT1A1;CYP2E1 28318:[DB06728 DB06737] DB06728|Aniline KLK1;ALB;CYP2E1 DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;PTGS1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;PTGS1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;UGT2B7;CYP2E1 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2E1;CYP2C9 28319:[DB06728 DB08655] DB06728|Aniline KLK1;ALB;CYP2E1 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways 28320:[DB06728 DB02360] DB06728|Aniline KLK1;ALB;CYP2E1 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways GO:0044267| cellular protein metabolic process CTSG;ALB GO:0006508| proteolysis CTSG;KLK1 28321:[DB06728 DB01866] DB06728|Aniline KLK1;ALB;CYP2E1 DB01866|RU79256 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC GO:0042493| response to drug CYP2E1;SRC 28322:[DB06728 DB07053] DB06728|Aniline KLK1;ALB;CYP2E1 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 28323:[DB06728 DB14583] DB06728|Aniline KLK1;ALB;CYP2E1 DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 28324:[DB06728 DB08867] DB06728|Aniline KLK1;ALB;CYP2E1 DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ORM1;ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2 28325:[DB06728 DB01251] DB06728|Aniline KLK1;ALB;CYP2E1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0042493| response to drug CYP2E1;ABCC8 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 28326:[DB06728 DB07265] DB06728|Aniline KLK1;ALB;CYP2E1 DB07265|3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID WEE1 common genes common pathways 28327:[DB06728 DB07450] DB06728|Aniline KLK1;ALB;CYP2E1 DB07450|(R)-minalrestat AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 28328:[DB06728 DB04942] DB06728|Aniline KLK1;ALB;CYP2E1 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways GO:0043066| negative regulation of apoptotic process RARB;ALB;RARA GO:0045471| response to ethanol CYP2E1;RARA 28329:[DB06728 DB09235] DB06728|Aniline KLK1;ALB;CYP2E1 DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28330:[DB06728 DB06943] DB06728|Aniline KLK1;ALB;CYP2E1 DB06943|(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol ADAM17 common genes common pathways GO:0042493| response to drug ADAM17;CYP2E1 GO:0006508| proteolysis KLK1;ADAM17 28331:[DB06728 DB04725] DB06728|Aniline KLK1;ALB;CYP2E1 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process ALOX5;PTGS2;CYP2J2;CYP2E1;CYP2C8;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2J2;CYP2C9;CYP2C8 GO:0098869| ALB;PTGS2 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2E1;UGT1A3 GO:0008202| steroid metabolic process CYP2E1;CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP2J2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 28332:[DB06728 DB00153] DB06728|Aniline KLK1;ALB;CYP2E1 DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP24A1;CYP2E1;CYP3A4;CYP27B1;CYP2R1;CYP27A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 28333:[DB06728 DB00358] DB06728|Aniline KLK1;ALB;CYP2E1 DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBA1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0098869| HBA1;ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6;CYP19A1 GO:0042493| response to drug CYP2E1;ABCB1;ADORA2A;BCHE 28334:[DB06728 DB00735] DB06728|Aniline KLK1;ALB;CYP2E1 DB00735|Naftifine SQLE common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;SQLE 28335:[DB06728 DB02846] DB06728|Aniline KLK1;ALB;CYP2E1 DB02846|L-thioproline ANXA5 common genes common pathways GO:0043066| negative regulation of apoptotic process ANXA5;ALB GO:0002576| platelet degranulation ALB;ANXA5 28336:[DB06728 DB03673] DB06728|Aniline KLK1;ALB;CYP2E1 DB03673|Beta(2-Thienyl)Alanine PAH common genes common pathways GO:0055114| oxidation-reduction process PAH;CYP2E1 28337:[DB06728 DB04867] DB06728|Aniline KLK1;ALB;CYP2E1 DB04867|Lintitript CCKAR common genes common pathways 28338:[DB06728 DB00770] DB06728|Aniline KLK1;ALB;CYP2E1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO3A1;ALB;SLCO2B1;SLCO2A1;SLC22A6 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0055114| oxidation-reduction process ABCC4;CYP2E1 GO:0042493| response to drug ABCC4;CYP2E1 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 28339:[DB06728 DB05956] DB06728|Aniline KLK1;ALB;CYP2E1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;ALB GO:0045471| response to ethanol GRIN2B;CYP2E1 28340:[DB06728 DB09256] DB06728|Aniline KLK1;ALB;CYP2E1 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP2A6;CYP2C8 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2A6;CYP3A5;CYP2C8 GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2E1;CYP2A6;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;TYMS GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2A6;CYP2C8 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP1A2;CYP2E1 GO:0045471| response to ethanol TYMS;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 28341:[DB06728 DB07416] DB06728|Aniline KLK1;ALB;CYP2E1 DB07416|(2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE IGKC common genes common pathways GO:0001895| retina homeostasis ALB;IGKC GO:0006898| receptor-mediated endocytosis IGKC;ALB GO:0006508| proteolysis IGKC;KLK1 28342:[DB06728 DB04967] DB06728|Aniline KLK1;ALB;CYP2E1 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0042493| response to drug APEX1;TOP1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;APEX1 GO:0010243| response to organic nitrogen APEX1;CYP2E1 28343:[DB06728 DB07422] DB06728|Aniline KLK1;ALB;CYP2E1 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways 28344:[DB06728 DB07205] DB06728|Aniline KLK1;ALB;CYP2E1 DB07205|N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE YARS common genes common pathways 28345:[DB06728 DB08788] DB06728|Aniline KLK1;ALB;CYP2E1 DB08788|3,6-DIAMINO-5-CYANO-4-(4-ETHOXYPHENYL)THIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 28346:[DB06728 DB09229] DB06728|Aniline KLK1;ALB;CYP2E1 DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ORM1;ALB GO:0042493| response to drug CYP2E1;ADRA1A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 28347:[DB06728 DB06094] DB06728|Aniline KLK1;ALB;CYP2E1 DB06094|Apatorsen HSPB1 common genes common pathways GO:0001895| retina homeostasis ALB;HSPB1 GO:0043066| negative regulation of apoptotic process ALB;HSPB1 28348:[DB06728 DB09078] DB06728|Aniline KLK1;ALB;CYP2E1 DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;FGFR2 GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2B6;CYP2C19;CYP2C8 GO:0043066| negative regulation of apoptotic process FLT4;ALB;KDR GO:0042493| response to drug ABCB1;ABCG2;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C19;CYP2C9;AOX1;CYP2B6 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2C9;AOX1;CYP2B6;CYP1A2;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A8;SLCO1B1 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2D6;CYP2C19;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;ABCB11 28349:[DB06728 DB05390] DB06728|Aniline KLK1;ALB;CYP2E1 DB05390|INS 316 P2RY2 common genes common pathways 28350:[DB06728 DB02366] DB06728|Aniline KLK1;ALB;CYP2E1 DB02366|CRA_10762 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 28351:[DB06728 DB08484] DB06728|Aniline KLK1;ALB;CYP2E1 DB08484|4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE FBP1 common genes common pathways 28352:[DB06728 DB04974] DB06728|Aniline KLK1;ALB;CYP2E1 DB04974|AP1903 MTOR common genes common pathways GO:0009267| cellular response to starvation ALB;MTOR 28353:[DB06728 DB02953] DB06728|Aniline KLK1;ALB;CYP2E1 DB02953|2-Thiomethyl-3-Phenylpropanoic Acid MMP8 common genes common pathways GO:0006508| proteolysis MMP8;KLK1 28354:[DB06728 DB00417] DB06728|Aniline KLK1;ALB;CYP2E1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 28355:[DB06728 DB02234] DB06728|Aniline KLK1;ALB;CYP2E1 DB02234|S-Ethylisothiourea NOS2;NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS2;NOS3;CYP2E1 28356:[DB06728 DB11691] DB06728|Aniline KLK1;ALB;CYP2E1 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0017144| drug metabolic process UGT1A3;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0055114| oxidation-reduction process CYP3A5;CYP3A7;CYP3A4;CYP2E1;CYP3A43 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28357:[DB06728 DB04471] DB06728|Aniline KLK1;ALB;CYP2E1 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways 28358:[DB06728 DB08045] DB06728|Aniline KLK1;ALB;CYP2E1 DB08045|4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL HSP90AB1 common genes common pathways GO:0043066| negative regulation of apoptotic process HSP90AB1;ALB GO:0042493| response to drug HSP90AB1;CYP2E1 GO:0006805| xenobiotic metabolic process HSP90AB1;CYP2E1 28359:[DB06728 DB06885] DB06728|Aniline KLK1;ALB;CYP2E1 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 28360:[DB06728 DB02263] DB06728|Aniline KLK1;ALB;CYP2E1 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO2A1;ALB 28361:[DB06728 DB03072] DB06728|Aniline KLK1;ALB;CYP2E1 DB03072|2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone PARP1 common genes common pathways 28362:[DB06728 DB06311] DB06728|Aniline KLK1;ALB;CYP2E1 DB06311|Darapladib PLA2G4A common genes common pathways 28363:[DB06728 DB02696] DB06728|Aniline KLK1;ALB;CYP2E1 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways 28364:[DB06728 DB08121] DB06728|Aniline KLK1;ALB;CYP2E1 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 28365:[DB06728 DB03192] DB06728|Aniline KLK1;ALB;CYP2E1 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HSD17B4 28366:[DB06728 DB14515] DB06728|Aniline KLK1;ALB;CYP2E1 DB14515|Magnesium lactate ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 28367:[DB06728 DB06985] DB06728|Aniline KLK1;ALB;CYP2E1 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways GO:0045471| response to ethanol RBP4;CYP2E1 28368:[DB06728 DB03405] DB06728|Aniline KLK1;ALB;CYP2E1 DB03405|N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 28369:[DB06728 DB07319] DB06728|Aniline KLK1;ALB;CYP2E1 DB07319|6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 28370:[DB06728 DB11157] DB06728|Aniline KLK1;ALB;CYP2E1 DB11157|Anthralin KRT2;MAPK8IP1;KRT12 common genes common pathways GO:0043066| negative regulation of apoptotic process MAPK8IP1;ALB 28371:[DB06728 DB08550] DB06728|Aniline KLK1;ALB;CYP2E1 DB08550|7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline PNMT common genes common pathways 28372:[DB06728 DB03267] DB06728|Aniline KLK1;ALB;CYP2E1 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 28373:[DB06728 DB00536] DB06728|Aniline KLK1;ALB;CYP2E1 DB00536|Guanidine argG;GAMT;RNASE1;DLG4;ALDH2;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A8;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0055114| oxidation-reduction process ALDH2;CYP2E1 28374:[DB06728 DB00701] DB06728|Aniline KLK1;ALB;CYP2E1 DB00701|Amprenavir pol;CYP3A4;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A5;ABCB1;ABCC1;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP2B6;CYP2C9;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C19;CYP2C8;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 28375:[DB06728 DB00738] DB06728|Aniline KLK1;ALB;CYP2E1 DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6;CYP2C19;CYP2C8;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP4A11;CYP2C8;CYP2C19;CYP1A1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0055114| oxidation-reduction process CYP4A11;CYP2E1;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP1A1 GO:0008202| steroid metabolic process CYP3A5;CYP2D6;CYP2C19;CYP2C8;CYP1A1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A1;CYP2D6;CYP2C8;CYP2C19 28376:[DB06728 DB12569] DB06728|Aniline KLK1;ALB;CYP2E1 DB12569|Tonapofylline ADORA1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADORA1 28377:[DB06728 DB03008] DB06728|Aniline KLK1;ALB;CYP2E1 DB03008|5-fluoro-beta-L-gulosyl fluoride MAN2A1 common genes common pathways 28378:[DB06728 DB03841] DB06728|Aniline KLK1;ALB;CYP2E1 DB03841|Y-700 XDH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;XDH 28379:[DB06728 DB09224] DB06728|Aniline KLK1;ALB;CYP2E1 DB09224|Melperone DRD2;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0042493| response to drug DRD2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0045471| response to ethanol DRD2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 28380:[DB06728 DB03882] DB06728|Aniline KLK1;ALB;CYP2E1 DB03882|5-Alpha-Androstane-3-Beta,17beta-Diol ESR2;SHBG common genes common pathways 28381:[DB06728 DB07234] DB06728|Aniline KLK1;ALB;CYP2E1 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways 28382:[DB06728 DB01248] DB06728|Aniline KLK1;ALB;CYP2E1 DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;NR1I2;CYP1B1;CYP3A5 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport SLCO1B3;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1B1;CYP3A5;NR1I2;CYP3A7;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLC22A7;SLCO1B3;ALB GO:0042493| response to drug CYP2E1;BCL2;ABCC1;ABCG2;ABCC2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP1B1 GO:0043066| negative regulation of apoptotic process ALB;BCL2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1B1 28383:[DB06728 DB05284] DB06728|Aniline KLK1;ALB;CYP2E1 DB05284|CA4P TUBB common genes common pathways 28384:[DB06728 DB08498] DB06728|Aniline KLK1;ALB;CYP2E1 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0006508| proteolysis KLK1;CASP3 GO:0042493| response to drug CASP3;CYP2E1 GO:0043066| negative regulation of apoptotic process CASP3;ALB 28385:[DB06728 DB01969] DB06728|Aniline KLK1;ALB;CYP2E1 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 28386:[DB06728 DB00172] DB06728|Aniline KLK1;ALB;CYP2E1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PPIF GO:0055114| oxidation-reduction process P3H2;PYCR2;P4HA2;PYCR1;CYP2E1;P3H3;PRODH;P4HA1;P3H1 28387:[DB06728 DB01989] DB06728|Aniline KLK1;ALB;CYP2E1 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways GO:0006508| proteolysis TLL2;KLK1 28388:[DB06728 DB00269] DB06728|Aniline KLK1;ALB;CYP2E1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1 28389:[DB06728 DB07906] DB06728|Aniline KLK1;ALB;CYP2E1 DB07906|[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL PNMT common genes common pathways 28390:[DB06728 DB02419] DB06728|Aniline KLK1;ALB;CYP2E1 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways 28391:[DB06728 DB00497] DB06728|Aniline KLK1;ALB;CYP2E1 DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP3A5 GO:0002576| platelet degranulation ORM1;ORM2;ALB GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 28392:[DB06728 DB12128] DB06728|Aniline KLK1;ALB;CYP2E1 DB12128|Ulimorelin GHSR common genes common pathways 28393:[DB06728 DB07405] DB06728|Aniline KLK1;ALB;CYP2E1 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 28394:[DB06728 DB08746] DB06728|Aniline KLK1;ALB;CYP2E1 DB08746|1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 28395:[DB06728 DB00711] DB06728|Aniline KLK1;ALB;CYP2E1 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE GO:0055114| oxidation-reduction process PTGS1;ALOX5;CYP2E1 GO:0098869| PTGS1;ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 28396:[DB06728 DB01326] DB06728|Aniline KLK1;ALB;CYP2E1 DB01326|Cefamandole SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A7;SLC22A11;SLC22A8 28397:[DB06728 DB07627] DB06728|Aniline KLK1;ALB;CYP2E1 DB07627|(2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE CAPN1 common genes common pathways GO:0006508| proteolysis CAPN1;KLK1 28398:[DB06728 DB05420] DB06728|Aniline KLK1;ALB;CYP2E1 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0055114| oxidation-reduction process RRM1;CYP2E1 28399:[DB06728 DB08903] DB06728|Aniline KLK1;ALB;CYP2E1 DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28400:[DB06728 DB08931] DB06728|Aniline KLK1;ALB;CYP2E1 DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP2J2;CYP3A4;CYP2C8 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2C8;CYP1A1;CYP2E1;CYP3A4 GO:0098869| ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP1A1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C8;CYP1A1;CYP3A4;CYP2E1;CYP2J2 GO:0042493| response to drug CYP2E1;CYP1A1;ABCG2 GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1;CYP2E1;CYP2J2 GO:0002576| platelet degranulation ALB;ORM1 28401:[DB06728 DB03187] DB06728|Aniline KLK1;ALB;CYP2E1 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 28402:[DB06728 DB01058] DB06728|Aniline KLK1;ALB;CYP2E1 DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A43 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP2C19;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19 28403:[DB06728 DB07329] DB06728|Aniline KLK1;ALB;CYP2E1 DB07329|1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID IGHG2 common genes common pathways GO:0006508| proteolysis KLK1;IGHG2 28404:[DB06728 DB05798] DB06728|Aniline KLK1;ALB;CYP2E1 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways 28405:[DB06728 DB05533] DB06728|Aniline KLK1;ALB;CYP2E1 DB05533|QR-333 AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 28406:[DB06728 DB08194] DB06728|Aniline KLK1;ALB;CYP2E1 DB08194|4-methyl-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-amine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 28407:[DB06728 DB07733] DB06728|Aniline KLK1;ALB;CYP2E1 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways GO:0006508| proteolysis KLK1;CASP1 28408:[DB06728 DB06961] DB06728|Aniline KLK1;ALB;CYP2E1 DB06961|5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 28409:[DB06728 DB14012] DB06728|Aniline KLK1;ALB;CYP2E1 DB14012|Burosumab FGF23 common genes common pathways GO:0044267| cellular protein metabolic process FGF23;ALB GO:0043687| post-translational protein modification FGF23;ALB 28410:[DB06728 DB07978] DB06728|Aniline KLK1;ALB;CYP2E1 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0042493| response to drug CYP2E1;DHODH GO:0055114| oxidation-reduction process CYP2E1;DHODH 28411:[DB06728 DB08735] DB06728|Aniline KLK1;ALB;CYP2E1 DB08735|R,S-Warfarin alcohol ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 28412:[DB06728 DB11300] DB06728|Aniline KLK1;ALB;CYP2E1 DB11300|Thrombin F2R;F2RL3;F11;F13A1;F13B;FGA;FGB;FGG;F5;F8 common genes common pathways GO:0044267| cellular protein metabolic process FGG;ALB;F5;FGA GO:0002576| platelet degranulation FGB;F5;FGA;ALB;F13A1;F8;FGG GO:0055114| oxidation-reduction process CYP2E1;F8 GO:0043687| post-translational protein modification FGG;FGA;F5;ALB GO:0006508| proteolysis KLK1;F11 28413:[DB06728 DB00332] DB06728|Aniline KLK1;ALB;CYP2E1 DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 28414:[DB06728 DB05025] DB06728|Aniline KLK1;ALB;CYP2E1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0042493| response to drug SOD1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;SOD1 GO:0043066| negative regulation of apoptotic process ALB;SOD1 GO:0002576| platelet degranulation SOD1;ALB GO:0001895| retina homeostasis ALB;SOD1 GO:0045471| response to ethanol CYP2E1;SOD1 28415:[DB06728 DB06824] DB06728|Aniline KLK1;ALB;CYP2E1 DB06824|Triethylenetetramine GPC1 common genes common pathways 28416:[DB06728 DB07174] DB06728|Aniline KLK1;ALB;CYP2E1 DB07174|6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-4-(3-METHOXYPROPYL)-2,2-DIMETHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE REN common genes common pathways GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug CYP2E1;REN 28417:[DB06728 DB06245] DB06728|Aniline KLK1;ALB;CYP2E1 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes KLK1 common pathways GO:0006898| receptor-mediated endocytosis ALB;LRP1;CALR GO:0006508| proteolysis KLK1;F10 GO:0044267| cellular protein metabolic process FN1;LAMB1;ALB;FGA;LAMC1 GO:0002576| platelet degranulation CLEC3B;ALB;FGA;FN1 GO:0043066| negative regulation of apoptotic process ALB;PLAUR;SERPINB2 GO:0042493| response to drug CYP2E1;CALR GO:0043687| post-translational protein modification FN1;LAMB1;ALB;FGA;LAMC1 28418:[DB06728 DB06780] DB06728|Aniline KLK1;ALB;CYP2E1 DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 28419:[DB06728 DB08010] DB06728|Aniline KLK1;ALB;CYP2E1 DB08010|(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways 28420:[DB06728 DB02510] DB06728|Aniline KLK1;ALB;CYP2E1 DB02510|'5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 28421:[DB06728 DB05424] DB06728|Aniline KLK1;ALB;CYP2E1 DB05424|Canertinib EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 28422:[DB06728 DB05219] DB06728|Aniline KLK1;ALB;CYP2E1 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8;CYP2B6;CYP2C9 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2C8;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C8;CYP2B6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9;CYP2B6;CYP2C8 28423:[DB06728 DB00890] DB06728|Aniline KLK1;ALB;CYP2E1 DB00890|Dienestrol ESR1;SHBG common genes common pathways 28424:[DB06728 DB05469] DB06728|Aniline KLK1;ALB;CYP2E1 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 28425:[DB06728 DB00991] DB06728|Aniline KLK1;ALB;CYP2E1 DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;PTGS1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0098869| ALB;PTGS2;PTGS1 28426:[DB06728 DB03003] DB06728|Aniline KLK1;ALB;CYP2E1 DB03003|Glutathione Sulfonic Acid gstA;GSTM4;GSTA1;GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP2E1 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0098869| GSTP1;GSTA1;ALB 28427:[DB06728 DB02750] DB06728|Aniline KLK1;ALB;CYP2E1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 28428:[DB06728 DB11638] DB06728|Aniline KLK1;ALB;CYP2E1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes ALB common pathways GO:0001895| retina homeostasis HSPB1;PRDX1;ALB;ACTG1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006508| proteolysis NPEPPS;KLK1 GO:0045471| response to ethanol CYP2E1;G6PD GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C19;CYP2D6;CYP2E1 GO:0044267| cellular protein metabolic process LGALS1;P4HB;ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP2D6;CYP2C19;UGT2B7;CYP2E1 GO:0009267| cellular response to starvation ALB;HSPA8 GO:0043252| sodium-independent organic anion transport ALB GO:0017144| drug metabolic process UGT1A9;CYP2C19;CYP2D6;CYP2E1 GO:0098869| ALB GO:0043687| post-translational protein modification ALB;P4HB;LGALS1 GO:0055114| oxidation-reduction process FTO;LDHA;GAPDHS;G6PD;PRDX1;LDHB;CYP2C19;ALDH7A1;CYP2D6;MDH1;P4HB;CYCS;CYP2E1;GAPDH GO:0042493| response to drug LDHA;CYP2E1;SRP14;LGALS1;HNRNPD GO:0002576| platelet degranulation ALDOA;FLNA;ALB;TAGLN2 GO:0043066| negative regulation of apoptotic process RPL10;CFL1;ALB;RPS6;HNRNPK;FLNA;NPM1;HSPB1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 28429:[DB06728 DB01161] DB06728|Aniline KLK1;ALB;CYP2E1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN3A;HTR3A;SLC6A3 GO:0042493| response to drug SLC6A3;BCHE;CYP2E1 28430:[DB06728 DB01870] DB06728|Aniline KLK1;ALB;CYP2E1 DB01870|1,4-dithio-alpha-D-glucopyranose AMY2B common genes common pathways 28431:[DB06728 DB06216] DB06728|Aniline KLK1;ALB;CYP2E1 DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0042493| response to drug DRD3;ADRA1A;DRD2;HTR1B;HTR2B;HTR2C;CYP1A2;CYP2E1;HTR2A;DRD1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0017144| drug metabolic process UGT1A4;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0045471| response to ethanol DRD3;DRD2;HTR1B;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 28432:[DB06728 DB07374] DB06728|Aniline KLK1;ALB;CYP2E1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0045471| response to ethanol CYP2E1;RPL15 28433:[DB06728 DB04882] DB06728|Aniline KLK1;ALB;CYP2E1 DB04882|Edotecarin TOP1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 28434:[DB06728 DB14637] DB06728|Aniline KLK1;ALB;CYP2E1 DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 28435:[DB06728 DB06451] DB06728|Aniline KLK1;ALB;CYP2E1 DB06451|Aprinocarsen PRKCA common genes common pathways 28436:[DB06728 DB07207] DB06728|Aniline KLK1;ALB;CYP2E1 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways GO:0006508| proteolysis F7;KLK1 28437:[DB06728 DB08547] DB06728|Aniline KLK1;ALB;CYP2E1 DB08547|PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0006508| proteolysis KLK1;IGHG2 28438:[DB06728 DB07488] DB06728|Aniline KLK1;ALB;CYP2E1 DB07488|{(2Z)-4-AMINO-2-[(4-METHOXYPHENYL)IMINO]-2,3-DIHYDRO-1,3-THIAZOL-5-YL}(4-METHOXYPHENYL)METHANONE CSNK1G3 common genes common pathways 28439:[DB06728 DB07922] DB06728|Aniline KLK1;ALB;CYP2E1 DB07922|N-oxo-2-(phenylsulfonylamino)ethanamide MMP12 common genes common pathways GO:0006508| proteolysis MMP12;KLK1 28440:[DB06728 DB00663] DB06728|Aniline KLK1;ALB;CYP2E1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 28441:[DB06728 DB00801] DB06728|Aniline KLK1;ALB;CYP2E1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug CYP2E1;GABRG3 28442:[DB06728 DB01282] DB06728|Aniline KLK1;ALB;CYP2E1 DB01282|Carbetocin OXTR common genes common pathways GO:0042493| response to drug CYP2E1;OXTR 28443:[DB06728 DB01143] DB06728|Aniline KLK1;ALB;CYP2E1 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ENPP1 28444:[DB06728 DB02715] DB06728|Aniline KLK1;ALB;CYP2E1 DB02715|Compound 18 ESR1 common genes common pathways 28445:[DB06728 DB00226] DB06728|Aniline KLK1;ALB;CYP2E1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0042493| response to drug CYP2E1;SLC6A2 28446:[DB06728 DB01373] DB06728|Aniline KLK1;ALB;CYP2E1 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0006508| proteolysis KLK1;PDCD6 GO:0006805| xenobiotic metabolic process CYP2E1;AOC1 GO:0045471| response to ethanol S100A8;CYP2E1 GO:0042493| response to drug CYP2E1;AOC1 GO:0055114| oxidation-reduction process AOC1;CP;CYP2E1 GO:0043687| post-translational protein modification ALB;BMP4;CP GO:0002576| platelet degranulation CALM1;ALB GO:0043066| negative regulation of apoptotic process BMP4;ALB;COMP GO:0044267| cellular protein metabolic process CP;BMP4;ALB GO:0098869| ALB;S100A9 28447:[DB06728 DB01321] DB06728|Aniline KLK1;ALB;CYP2E1 DB01321|Josamycin rplD;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 28448:[DB06728 DB01915] DB06728|Aniline KLK1;ALB;CYP2E1 DB01915|S-Hydroxycysteine C3;GSTP1;ACAT2;GSTA1;PMP2 common genes common pathways GO:0098869| GSTP1;GSTA1;ALB GO:0044267| cellular protein metabolic process C3;ALB GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0043687| post-translational protein modification ALB;C3 GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0006508| proteolysis KLK1;C3 28449:[DB06728 DB00631] DB06728|Aniline KLK1;ALB;CYP2E1 DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;CYP2E1 GO:0055114| oxidation-reduction process RRM1;CYP2E1 28450:[DB06728 DB07593] DB06728|Aniline KLK1;ALB;CYP2E1 DB07593|1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE CTSK common genes common pathways GO:0006508| proteolysis KLK1;CTSK 28451:[DB06728 DB08361] DB06728|Aniline KLK1;ALB;CYP2E1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways 28452:[DB06728 DB11136] DB06728|Aniline KLK1;ALB;CYP2E1 DB11136|Chromium CYB5A;TF common genes common pathways GO:0001895| retina homeostasis TF;ALB GO:0044267| cellular protein metabolic process ALB;TF GO:0043687| post-translational protein modification ALB;TF GO:0055114| oxidation-reduction process CYP2E1;CYB5A GO:0002576| platelet degranulation TF;ALB 28453:[DB06728 DB07159] DB06728|Aniline KLK1;ALB;CYP2E1 DB07159|Tamatinib SYK common genes common pathways 28454:[DB06728 DB09209] DB06728|Aniline KLK1;ALB;CYP2E1 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 28455:[DB06728 DB00114] DB06728|Aniline KLK1;ALB;CYP2E1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0055114| oxidation-reduction process PNPO;CYP2E1;CBS;GLDC GO:0042493| response to drug GAD2;SRR;GAD1;ABAT;CYP2E1 GO:0043066| negative regulation of apoptotic process CTH;ALB GO:0045471| response to ethanol CYP2E1;ABAT;GOT2 28456:[DB06728 DB02931] DB06728|Aniline KLK1;ALB;CYP2E1 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways 28457:[DB06728 DB05513] DB06728|Aniline KLK1;ALB;CYP2E1 DB05513|Atiprimod IL6;TNF common genes common pathways GO:0043687| post-translational protein modification ALB;IL6 GO:0043066| negative regulation of apoptotic process IL6;ALB GO:0044267| cellular protein metabolic process ALB;IL6 28458:[DB06728 DB02269] DB06728|Aniline KLK1;ALB;CYP2E1 DB02269|[4-({[5-Benzyloxy-1-(3-Carbamimidoyl-Benzyl)-1h-Indole-2-Carbonyl]-Amino}-Methyl)-Phenyl]-Trimethyl-Ammonium PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 28459:[DB06728 DB11091] DB06728|Aniline KLK1;ALB;CYP2E1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0045471| response to ethanol CYP2E1;CAT GO:0006641| triglyceride metabolic process GPX1;CAT;CYP2E1 GO:0042493| response to drug CYP2E1;CAT GO:0055114| oxidation-reduction process GPX1;CAT;CYP2E1 GO:0043066| negative regulation of apoptotic process GPX1;CAT;ALB GO:0010193| response to ozone CAT;CYP2E1 GO:0098869| ALB;GPX1;CAT 28460:[DB06728 DB13179] DB06728|Aniline KLK1;ALB;CYP2E1 DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1;CYP2C18 GO:0055114| oxidation-reduction process CYP2C8;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP3A7;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process NR1I2;CYP2C9;CYP2C8;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C18;CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;NR1I2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 28461:[DB06728 DB13153] DB06728|Aniline KLK1;ALB;CYP2E1 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 28462:[DB06728 DB01435] DB06728|Aniline KLK1;ALB;CYP2E1 DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes CYP2E1 common pathways GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2C18;CYP1A2;CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2A6;CYP2E1;CYP2C18;CYP2B6;CYP2C9;CYP2C8;CYP2C19 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0018910| benzene metabolic process CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C18;PTGS1;CYP2E1;CYP3A4;CYP2A6;CYP1A2;PTGS2;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP2B6 GO:0098869| ALB;PTGS1;PTGS2 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2E1;CYP2A6 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2C9;CYP2A6;CYP3A4;CYP2E1;CYP1A2 GO:0010193| response to ozone CYP2E1 28463:[DB06728 DB08340] DB06728|Aniline KLK1;ALB;CYP2E1 DB08340|N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE CSNK2A1 common genes common pathways 28464:[DB06728 DB08175] DB06728|Aniline KLK1;ALB;CYP2E1 DB08175|(2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID NCOA2;RXRB;NR1H3 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 28465:[DB06728 DB11640] DB06728|Aniline KLK1;ALB;CYP2E1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;NAT2;NAT1 28466:[DB06728 DB08270] DB06728|Aniline KLK1;ALB;CYP2E1 DB08270|N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 28467:[DB06728 DB02860] DB06728|Aniline KLK1;ALB;CYP2E1 DB02860|Calyculin A PPP1CC common genes common pathways 28468:[DB06728 DB00197] DB06728|Aniline KLK1;ALB;CYP2E1 DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP2C19;CYP2C8;CYP3A5;UGT2B15;UGT1A9;CYP2B6;CYP2C9;UGT1A6;CYP3A7;CYP3A4;CYP2E1 GO:0045471| response to ethanol GSTP1;UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1;ACSL4 GO:0002576| platelet degranulation SERPINE1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8;CYP2C9;CYP1A1;CYP2B6 GO:0043066| negative regulation of apoptotic process PPARD;ALB;GSTP1 GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A5;CYP2B6;CYP19A1;CYP1A1;CYP2C9;CYP3A4;CYP2E1;CYP3A7 GO:0042493| response to drug CYP2E1;CYP1A1;PPARG;UGT1A1 GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;UGT1A4;UGT1A8;UGT1A9;CYP2C9;CYP1A1;CYP2B6;UGT1A3;UGT1A10;UGT1A6;CYP2E1;CYP3A4;UGT1A7 GO:0098869| ALB;GSTP1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process UGT1A1;UGT1A8;UGT2B15;CYP2C9;CYP1A1;CYP2B6;CYP3A5;CYP2C8;CYP2C19;CYP3A7;CYP2E1;CYP3A4;UGT2B7 GO:0015721| bile acid and bile salt transport ALB;ABCB11;SLCO1B1 28469:[DB06728 DB01186] DB06728|Aniline KLK1;ALB;CYP2E1 DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug DRD3;HTR2B;HTR2C;HTR1B;ADRA1A;DRD2;HTR2A;CYP2E1;DRD1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol HTR1B;DRD2;DRD3;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 28470:[DB06728 DB00020] DB06728|Aniline KLK1;ALB;CYP2E1 DB00020|Sargramostim CSF2RA;IL3RA;CSF2RB;SDC2;PRG2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;CSF2RB;SDC2;CSF2RA GO:0043687| post-translational protein modification SDC2;ALB 28471:[DB06728 DB03193] DB06728|Aniline KLK1;ALB;CYP2E1 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes ALB common pathways GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug CYP2E1;FABP3 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28472:[DB06728 DB02258] DB06728|Aniline KLK1;ALB;CYP2E1 DB02258|SR11254 RARG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 28473:[DB06728 DB00795] DB06728|Aniline KLK1;ALB;CYP2E1 DB00795|Sulfasalazine ALOX5;PTGS2;PTGS1;PPARG;CHUK;IKBKB;SLC7A11;ACAT1;TBXAS1;PLA2G1B;ABCG2;ABCC2;SLC46A1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB;SLCO2B1 GO:0098869| PTGS1;PTGS2;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1B3;SLCO1B1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2;IKBKB GO:0055114| oxidation-reduction process TBXAS1;ALOX5;PTGS1;PTGS2;CYP2E1 GO:0042493| response to drug ABCG2;ABCC2;PPARG;CHUK;CYP2E1;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 28474:[DB06728 DB11569] DB06728|Aniline KLK1;ALB;CYP2E1 DB11569|Ixekizumab IL17A common genes common pathways 28475:[DB06728 DB01032] DB06728|Aniline KLK1;ALB;CYP2E1 DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLC10A1;SLCO1C1;ABCC3;SLCO1A2 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLC22A7;SLC22A12;SLC22A11;SLC22A8;SLCO1A2;ALB;SLC22A10;SLC22A6;SLCO1C1 GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP2C8;CYP2C19;UGT1A1;CYP2E1;CYP3A4 GO:0098869| ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;ABCC4;CYP2C19;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug UGT1A1;ABCC6;ABCC1;ABCC2;CYP2E1;SLC22A12;ABCC4 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8;CYP2C19 GO:0002576| platelet degranulation ABCC4;ALB 28476:[DB06728 DB06345] DB06728|Aniline KLK1;ALB;CYP2E1 DB06345|AR-9281 EPHX2 common genes common pathways GO:0006805| xenobiotic metabolic process EPHX2;CYP2E1 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2E1 GO:0017144| drug metabolic process EPHX2;CYP2E1 28477:[DB06728 DB08738] DB06728|Aniline KLK1;ALB;CYP2E1 DB08738|1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one PREP common genes common pathways GO:0006508| proteolysis KLK1;PREP 28478:[DB06728 DB01130] DB06728|Aniline KLK1;ALB;CYP2E1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 28479:[DB06728 DB06151] DB06728|Aniline KLK1;ALB;CYP2E1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0006508| proteolysis ACY1;KLK1 GO:0045471| response to ethanol GRIN2B;CYP2E1;GRIN1;GRIN2A;GRIN3A GO:0006805| xenobiotic metabolic process ACY1;CYP2E1 GO:0042493| response to drug CYP2E1;GRIN2A;CHUK GO:0043066| negative regulation of apoptotic process IKBKB;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLC22A6;ALB 28480:[DB06728 DB07125] DB06728|Aniline KLK1;ALB;CYP2E1 DB07125|4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid DAPK3 common genes common pathways 28481:[DB06728 DB03704] DB06728|Aniline KLK1;ALB;CYP2E1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0055114| oxidation-reduction process ADH5;CYP2E1 28482:[DB06728 DB06634] DB06728|Aniline KLK1;ALB;CYP2E1 DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0010193| response to ozone TACR1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;TACR1 28483:[DB06728 DB05024] DB06728|Aniline KLK1;ALB;CYP2E1 DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;CYP2E1 28484:[DB06728 DB09488] DB06728|Aniline KLK1;ALB;CYP2E1 DB09488|Acrivastine HRH1 common genes common pathways 28485:[DB06728 DB00628] DB06728|Aniline KLK1;ALB;CYP2E1 DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug TSPO;CYP2E1;GABRG3 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;TSPO 28486:[DB06728 DB09089] DB06728|Aniline KLK1;ALB;CYP2E1 DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol OPRM1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28487:[DB06728 DB08869] DB06728|Aniline KLK1;ALB;CYP2E1 DB08869|Tesamorelin GHRHR common genes common pathways 28488:[DB06728 DB09570] DB06728|Aniline KLK1;ALB;CYP2E1 DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6;CYP2B6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2C8 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19 28489:[DB06728 DB08676] DB06728|Aniline KLK1;ALB;CYP2E1 DB08676|(20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways 28490:[DB06728 DB08815] DB06728|Aniline KLK1;ALB;CYP2E1 DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0042493| response to drug DRD2;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol DRD2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28491:[DB06728 DB03509] DB06728|Aniline KLK1;ALB;CYP2E1 DB03509|2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide PARP1 common genes common pathways 28492:[DB06728 DB00400] DB06728|Aniline KLK1;ALB;CYP2E1 DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 28493:[DB06728 DB07465] DB06728|Aniline KLK1;ALB;CYP2E1 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28494:[DB06728 DB02069] DB06728|Aniline KLK1;ALB;CYP2E1 DB02069|N-(2-Flouro-Benzyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways 28495:[DB06728 DB03507] DB06728|Aniline KLK1;ALB;CYP2E1 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways 28496:[DB06728 DB07662] DB06728|Aniline KLK1;ALB;CYP2E1 DB07662|N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE SRC;EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;EGFR;ALB GO:0042493| response to drug SRC;CYP2E1 28497:[DB06728 DB06422] DB06728|Aniline KLK1;ALB;CYP2E1 DB06422|Ticalopride HTR4;HTR3A common genes common pathways GO:0045471| response to ethanol CYP2E1;HTR3A 28498:[DB06728 DB05869] DB06728|Aniline KLK1;ALB;CYP2E1 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways 28499:[DB06728 DB01629] DB06728|Aniline KLK1;ALB;CYP2E1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0043066| negative regulation of apoptotic process SOD1;ALB GO:0002576| platelet degranulation SOD1;ALB GO:0055114| oxidation-reduction process CYP2E1;SOD1 GO:0042493| response to drug SOD1;CYP2E1 GO:0045471| response to ethanol CYP2E1;SOD1 GO:0001895| retina homeostasis SOD1;ALB 28500:[DB06728 DB12478] DB06728|Aniline KLK1;ALB;CYP2E1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 GO:0042493| response to drug DRD3;DRD2;CYP2E1 28501:[DB06728 DB00468] DB06728|Aniline KLK1;ALB;CYP2E1 DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes CYP2E1 common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C19;CYP1A1;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP1A1;CYP2C19;CYP2C8;CYP2D6;CYP3A5 GO:0010193| response to ozone CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9;CYP1A1;CYP2C8;CYP2C19 GO:0018910| benzene metabolic process CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP1A1;ABCB1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP2C9;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1 28502:[DB06728 DB02936] DB06728|Aniline KLK1;ALB;CYP2E1 DB02936|4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid PLA2G2A common genes common pathways 28503:[DB06728 DB02148] DB06728|Aniline KLK1;ALB;CYP2E1 DB02148|3-Amino-4-Oxybenzyl-2-Butanone CTSB common genes common pathways GO:0006508| proteolysis KLK1;CTSB 28504:[DB06728 DB02449] DB06728|Aniline KLK1;ALB;CYP2E1 DB02449|3-(1h-Indol-3-Yl)-2-[4-(4-Phenyl-Piperidin-1-Yl)-Benzenesulfonylamino]-Propionic Acid MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 28505:[DB06728 DB02335] DB06728|Aniline KLK1;ALB;CYP2E1 DB02335|2-Aminothiazoline NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 28506:[DB06728 DB07387] DB06728|Aniline KLK1;ALB;CYP2E1 DB07387|3-(BUTYLSULPHONYL)-PROPANOIC ACID TPI1 common genes common pathways 28507:[DB06728 DB01021] DB06728|Aniline KLK1;ALB;CYP2E1 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 28508:[DB06728 DB00824] DB06728|Aniline KLK1;ALB;CYP2E1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0044267| cellular protein metabolic process ADORA2B;ALB;ADORA2A GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0042493| response to drug CYP2E1;ADORA2A 28509:[DB06728 DB03175] DB06728|Aniline KLK1;ALB;CYP2E1 DB03175|Propyl alcohol LYZ common genes common pathways GO:0001895| retina homeostasis ALB;LYZ GO:0044267| cellular protein metabolic process ALB;LYZ 28510:[DB06728 DB11834] DB06728|Aniline KLK1;ALB;CYP2E1 DB11834|Guselkumab IL23A common genes common pathways 28511:[DB06728 DB08906] DB06728|Aniline KLK1;ALB;CYP2E1 DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2E1 28512:[DB06728 DB02318] DB06728|Aniline KLK1;ALB;CYP2E1 DB02318|2-deoxy-2-fluoro-alpha-D-mannosyl fluoride MAN2A1 common genes common pathways 28513:[DB06728 DB02546] DB06728|Aniline KLK1;ALB;CYP2E1 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0042493| response to drug HDAC2;CYP2E1;HDAC1 GO:0043066| negative regulation of apoptotic process HDAC2;HDAC3;ALB;HDAC1 28514:[DB06728 DB00848] DB06728|Aniline KLK1;ALB;CYP2E1 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways 28515:[DB06728 DB04947] DB06728|Aniline KLK1;ALB;CYP2E1 DB04947|Altropane SLC6A3 common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0042493| response to drug SLC6A3;CYP2E1 28516:[DB06728 DB01860] DB06728|Aniline KLK1;ALB;CYP2E1 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 28517:[DB06728 DB04080] DB06728|Aniline KLK1;ALB;CYP2E1 DB04080|RU78191 SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process SRC;ALB 28518:[DB06728 DB02917] DB06728|Aniline KLK1;ALB;CYP2E1 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways 28519:[DB06728 DB11124] DB06728|Aniline KLK1;ALB;CYP2E1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 28520:[DB06728 DB02226] DB06728|Aniline KLK1;ALB;CYP2E1 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 28521:[DB06728 DB09018] DB06728|Aniline KLK1;ALB;CYP2E1 DB09018|Bromopride DRD2 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug DRD2;CYP2E1 28522:[DB06728 DB01096] DB06728|Aniline KLK1;ALB;CYP2E1 DB01096|Oxamniquine CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 28523:[DB06728 DB06587] DB06728|Aniline KLK1;ALB;CYP2E1 DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 28524:[DB06728 DB05990] DB06728|Aniline KLK1;ALB;CYP2E1 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0043066| negative regulation of apoptotic process NR1H4;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0015721| bile acid and bile salt transport NR1H4;ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 28525:[DB06728 DB06061] DB06728|Aniline KLK1;ALB;CYP2E1 DB06061|AZD-8330 MAP3K1 common genes common pathways 28526:[DB06728 DB05797] DB06728|Aniline KLK1;ALB;CYP2E1 DB05797|TNX-901 FCER1A common genes common pathways 28527:[DB06728 DB07402] DB06728|Aniline KLK1;ALB;CYP2E1 DB07402|Azapropazone ALB common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 28528:[DB06728 DB04700] DB06728|Aniline KLK1;ALB;CYP2E1 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways GO:0055114| oxidation-reduction process GSTK1;CYP2E1 GO:0098869| ALB;GSTK1 28529:[DB06728 DB04593] DB06728|Aniline KLK1;ALB;CYP2E1 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways GO:0006508| proteolysis KLK1;F7 28530:[DB06728 DB08054] DB06728|Aniline KLK1;ALB;CYP2E1 DB08054|1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process SRC;ALB 28531:[DB06728 DB03082] DB06728|Aniline KLK1;ALB;CYP2E1 DB03082|6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 28532:[DB06728 DB02209] DB06728|Aniline KLK1;ALB;CYP2E1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0055114| oxidation-reduction process PNPO;CYP2E1 28533:[DB06728 DB05088] DB06728|Aniline KLK1;ALB;CYP2E1 DB05088|Tiomolibdate ion APP common genes common pathways GO:0043687| post-translational protein modification ALB;APP GO:0002576| platelet degranulation APP;ALB GO:0044267| cellular protein metabolic process APP;ALB 28534:[DB06728 DB09241] DB06728|Aniline KLK1;ALB;CYP2E1 DB09241|Methylene blue GUCY1A2;NOS1 common genes common pathways GO:0055114| oxidation-reduction process NOS1;CYP2E1 28535:[DB06728 DB04351] DB06728|Aniline KLK1;ALB;CYP2E1 DB04351|Aconitate Ion ACO2 common genes common pathways 28536:[DB06728 DB08590] DB06728|Aniline KLK1;ALB;CYP2E1 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways 28537:[DB06728 DB05749] DB06728|Aniline KLK1;ALB;CYP2E1 DB05749|MPI-674 CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP19A1 28538:[DB06728 DB09363] DB06728|Aniline KLK1;ALB;CYP2E1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOB;MAOA;CYP2E1 GO:0042493| response to drug CYP2E1;MAOB;SLC6A2 28539:[DB06728 DB00912] DB06728|Aniline KLK1;ALB;CYP2E1 DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 GO:0042493| response to drug PPARG;CYP2E1;ABCC8 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;ABCB11 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0098869| ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 28540:[DB06728 DB04888] DB06728|Aniline KLK1;ALB;CYP2E1 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0042493| response to drug DRD2;CYP2E1 28541:[DB06728 DB01858] DB06728|Aniline KLK1;ALB;CYP2E1 DB01858|[1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 28542:[DB06728 DB14010] DB06728|Aniline KLK1;ALB;CYP2E1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug HTR2A;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 28543:[DB06728 DB01256] DB06728|Aniline KLK1;ALB;CYP2E1 DB01256|Retapamulin rplC;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 28544:[DB06728 DB00944] DB06728|Aniline KLK1;ALB;CYP2E1 DB00944|Demecarium ACHE;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 28545:[DB06728 DB14509] DB06728|Aniline KLK1;ALB;CYP2E1 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0043066| negative regulation of apoptotic process GSK3B;ALB 28546:[DB06728 DB04345] DB06728|Aniline KLK1;ALB;CYP2E1 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways GO:0055114| oxidation-reduction process BLVRB;CYP2E1 28547:[DB06728 DB04836] DB06728|Aniline KLK1;ALB;CYP2E1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A4;CYP2E1;SLC6A2 28548:[DB06728 DB13192] DB06728|Aniline KLK1;ALB;CYP2E1 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways GO:0006508| proteolysis KLK1;PROC;F10;F9 GO:0043066| negative regulation of apoptotic process PROC;ALB GO:0043687| post-translational protein modification PROC;ALB GO:0044267| cellular protein metabolic process ALB;PROC 28549:[DB06728 DB00211] DB06728|Aniline KLK1;ALB;CYP2E1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug CYP2E1;ADRA1A GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 28550:[DB06728 DB01564] DB06728|Aniline KLK1;ALB;CYP2E1 DB01564|Calusterone AR common genes common pathways 28551:[DB06728 DB08895] DB06728|Aniline KLK1;ALB;CYP2E1 DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0098869| ALB GO:0008202| steroid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 28552:[DB06728 DB01324] DB06728|Aniline KLK1;ALB;CYP2E1 DB01324|Polythiazide SLC12A3 common genes common pathways 28553:[DB06728 DB03058] DB06728|Aniline KLK1;ALB;CYP2E1 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways GO:0002576| platelet degranulation ALB;CFD GO:0006508| proteolysis KLK1;CFD 28554:[DB06728 DB05005] DB06728|Aniline KLK1;ALB;CYP2E1 DB05005|CCX282 CCR9 common genes common pathways 28555:[DB06728 DB03759] DB06728|Aniline KLK1;ALB;CYP2E1 DB03759|FG-9041 GRIA2 common genes common pathways 28556:[DB06728 DB08008] DB06728|Aniline KLK1;ALB;CYP2E1 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0042493| response to drug DHODH;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;DHODH 28557:[DB06728 DB08063] DB06728|Aniline KLK1;ALB;CYP2E1 DB08063|1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE RXRA;NR1H3 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA 28558:[DB06728 DB01754] DB06728|Aniline KLK1;ALB;CYP2E1 DB01754|3,4-Dihydroxy-1-Methylquinolin-2(1h)-One PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;ALB 28559:[DB06728 DB14539] DB06728|Aniline KLK1;ALB;CYP2E1 DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP3A4;CYP2E1;CYP3A7;CYP11B1;CYP11B2 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB GO:0055114| oxidation-reduction process CYP3A5;HSD11B2;HSD3B1;CYP2C8;CYP3A7;CYP11B1;CYP11B2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCG2;ANXA1;HSD11B2;ABCB1 GO:0043066| negative regulation of apoptotic process ANXA1;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 28560:[DB06728 DB03686] DB06728|Aniline KLK1;ALB;CYP2E1 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0098869| ALB;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB 28561:[DB06728 DB03309] DB06728|Aniline KLK1;ALB;CYP2E1 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways GO:0008202| steroid metabolic process SULT2B1;CYP2E1 28562:[DB06728 DB08118] DB06728|Aniline KLK1;ALB;CYP2E1 DB08118|2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 28563:[DB06728 DB04003] DB06728|Aniline KLK1;ALB;CYP2E1 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways GO:0042493| response to drug CYP2E1;LCK 28564:[DB06728 DB04767] DB06728|Aniline KLK1;ALB;CYP2E1 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways GO:0006508| proteolysis F7;KLK1 28565:[DB06728 DB04579] DB06728|Aniline KLK1;ALB;CYP2E1 DB04579|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}- CTSB common genes common pathways GO:0006508| proteolysis CTSB;KLK1 28566:[DB06728 DB00863] DB06728|Aniline KLK1;ALB;CYP2E1 DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP3A5;CYP2D6;CYP2C19 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;BCHE;ABCB1 28567:[DB06728 DB12965] DB06728|Aniline KLK1;ALB;CYP2E1 DB12965|Silver MTF1;MT1HL1;MT1A;MT1B;MT1E;MT1F;MT1G;MT1H;MT1L;MT1M;MT1X;MT2A;MT3;MT4;MT1DP;TESMIN;CP;ALB;A2M common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification CP;ALB GO:0055114| oxidation-reduction process CP;CYP2E1 GO:0002576| platelet degranulation ALB;A2M GO:0043066| negative regulation of apoptotic process ALB;MT3 GO:0044267| cellular protein metabolic process ALB;CP GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB 28568:[DB06728 DB01784] DB06728|Aniline KLK1;ALB;CYP2E1 DB01784|4-Flourobenzenesulfonamide CA2 common genes common pathways 28569:[DB06728 DB07195] DB06728|Aniline KLK1;ALB;CYP2E1 DB07195|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 28570:[DB06728 DB05885] DB06728|Aniline KLK1;ALB;CYP2E1 DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28571:[DB06728 DB08430] DB06728|Aniline KLK1;ALB;CYP2E1 DB08430|PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE LCTL common genes common pathways 28572:[DB06728 DB11127] DB06728|Aniline KLK1;ALB;CYP2E1 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;GPX1 GO:0055114| oxidation-reduction process TXNRD1;GPX1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;GPX1 GO:0098869| TXNRD1;GPX1;ALB 28573:[DB06728 DB03429] DB06728|Aniline KLK1;ALB;CYP2E1 DB03429|Cardiolipin SLC25A4 common genes common pathways 28574:[DB06728 DB04417] DB06728|Aniline KLK1;ALB;CYP2E1 DB04417|P-Nitrophenol SULT1A1;AMY2B common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;SULT1A1 GO:0008202| steroid metabolic process CYP2E1;SULT1A1 28575:[DB06728 DB09204] DB06728|Aniline KLK1;ALB;CYP2E1 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;ADRA1A GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;ORM1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 28576:[DB06728 DB08388] DB06728|Aniline KLK1;ALB;CYP2E1 DB08388|5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE MMP13 common genes common pathways GO:0044267| cellular protein metabolic process MMP13;ALB GO:0006508| proteolysis KLK1;MMP13 28577:[DB06728 DB08826] DB06728|Aniline KLK1;ALB;CYP2E1 DB08826|Deferiprone UGT1A6 common genes common pathways GO:0006805| xenobiotic metabolic process UGT1A6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;UGT1A6 28578:[DB06728 DB08588] DB06728|Aniline KLK1;ALB;CYP2E1 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 28579:[DB06728 DB07415] DB06728|Aniline KLK1;ALB;CYP2E1 DB07415|4-[(1S)-1-(3-fluoro-4-methoxyphenyl)-2-(2-methoxy-5-nitrophenyl)ethyl]-1H-imidazol-2-amine BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process BACE1;ALB 28580:[DB06728 DB01205] DB06728|Aniline KLK1;ALB;CYP2E1 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug CYP2E1;GABRG3 28581:[DB06728 DB09185] DB06728|Aniline KLK1;ALB;CYP2E1 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1;SLC6A2 28582:[DB06728 DB08643] DB06728|Aniline KLK1;ALB;CYP2E1 DB08643|2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 28583:[DB06728 DB08504] DB06728|Aniline KLK1;ALB;CYP2E1 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 28584:[DB06728 DB00285] DB06728|Aniline KLK1;ALB;CYP2E1 DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C9;CYP2C19 GO:0042493| response to drug SLC6A2;ABCG2;SLC6A3;ABCB1;CYP2E1;SLC6A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9;CYP2B6;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2B6;CYP2C9;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP2C19;CYP2D6 28585:[DB06728 DB03696] DB06728|Aniline KLK1;ALB;CYP2E1 DB03696|Lanosterol LSS common genes common pathways 28586:[DB06728 DB06013] DB06728|Aniline KLK1;ALB;CYP2E1 DB06013|Aldoxorubicin TOP2A common genes common pathways 28587:[DB06728 DB05968] DB06728|Aniline KLK1;ALB;CYP2E1 DB05968|PR-104 TNF common genes common pathways 28588:[DB06728 DB01919] DB06728|Aniline KLK1;ALB;CYP2E1 DB01919|Pentanal PRKACA common genes common pathways 28589:[DB06728 DB02045] DB06728|Aniline KLK1;ALB;CYP2E1 DB02045|Amylamine PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 28590:[DB06728 DB14004] DB06728|Aniline KLK1;ALB;CYP2E1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP4A11 GO:0055114| oxidation-reduction process CYP2E1;CYP4A11 28591:[DB06728 DB00708] DB06728|Aniline KLK1;ALB;CYP2E1 DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol OPRK1;OPRM1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 28592:[DB06728 DB09148] DB06728|Aniline KLK1;ALB;CYP2E1 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2J2;CYP2E1 GO:0043687| post-translational protein modification ALB;APP GO:0055114| oxidation-reduction process CYP4F2;CYP2J2;CYP2E1 GO:0002576| platelet degranulation ALB;APP GO:0019373| epoxygenase P450 pathway CYP2J2;CYP2E1;CYP4F2 GO:0044267| cellular protein metabolic process ALB;APP GO:0017144| drug metabolic process CYP2E1;CYP4F2 28593:[DB06728 DB02401] DB06728|Aniline KLK1;ALB;CYP2E1 DB02401|4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid LDHB common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;LDHB 28594:[DB06728 DB03167] DB06728|Aniline KLK1;ALB;CYP2E1 DB03167|Pentabromophenol TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 28595:[DB06728 DB08782] DB06728|Aniline KLK1;ALB;CYP2E1 DB08782|4-(2-AMINOETHYL)BENZENESULFONAMIDE CA2 common genes common pathways 28596:[DB06728 DB00390] DB06728|Aniline KLK1;ALB;CYP2E1 DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B3;SLCO1B1;ABCB11;SLCO2B1;ALB;SLC51B;SLCO1C1;SLC51A GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP11A1 GO:0043252| sodium-independent organic anion transport SLCO4C1;ALB;SLCO2B1;SLCO1C1;SLCO4A1;SLCO1A2;SLCO1B3;SLCO1B1;SLC22A8 GO:0042493| response to drug CYP2E1;ATP1A1;ABCB1 GO:0055114| oxidation-reduction process CYP11A1;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 28597:[DB06728 DB05786] DB06728|Aniline KLK1;ALB;CYP2E1 DB05786|Irofulven FUBP1 common genes common pathways 28598:[DB06728 DB00407] DB06728|Aniline KLK1;ALB;CYP2E1 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways GO:0043687| post-translational protein modification SERPINC1;SERPIND1;ALB GO:0044267| cellular protein metabolic process SERPIND1;SERPINC1;ALB 28599:[DB06728 DB02279] DB06728|Aniline KLK1;ALB;CYP2E1 DB02279|Benzoylformic Acid HAO1 common genes common pathways GO:0055114| oxidation-reduction process HAO1;CYP2E1 28600:[DB06728 DB08338] DB06728|Aniline KLK1;ALB;CYP2E1 DB08338|19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one CSNK2A1 common genes common pathways 28601:[DB06728 DB07897] DB06728|Aniline KLK1;ALB;CYP2E1 DB07897|1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 28602:[DB06728 DB00966] DB06728|Aniline KLK1;ALB;CYP2E1 DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19 GO:0042493| response to drug CYP2E1;PPARG;ABCC2;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1;UGT1A3 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C19 28603:[DB06728 DB04172] DB06728|Aniline KLK1;ALB;CYP2E1 DB04172|[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 28604:[DB06728 DB06907] DB06728|Aniline KLK1;ALB;CYP2E1 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 28605:[DB06728 DB04217] DB06728|Aniline KLK1;ALB;CYP2E1 DB04217|L-2-amino-3-butynoic acid CTH;sufS common genes common pathways GO:0043066| negative regulation of apoptotic process CTH;ALB 28606:[DB06728 DB05014] DB06728|Aniline KLK1;ALB;CYP2E1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0043066| negative regulation of apoptotic process PDGFRB;ALB;KDR GO:0010243| response to organic nitrogen CYP2E1;FLT3 GO:0042493| response to drug RET;CYP2E1 28607:[DB06728 DB07713] DB06728|Aniline KLK1;ALB;CYP2E1 DB07713|(1S)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid MMP8 common genes common pathways GO:0006508| proteolysis MMP8;KLK1 28608:[DB06728 DB11590] DB06728|Aniline KLK1;ALB;CYP2E1 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| GPX1;ALB;GSR GO:0055114| oxidation-reduction process SOD2;GSR;CYP2E1;GPX1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB;GPX1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006641| triglyceride metabolic process GPX1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28609:[DB06728 DB08607] DB06728|Aniline KLK1;ALB;CYP2E1 DB08607|(5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE CYP2C8;FABP4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2E1 28610:[DB06728 DB02153] DB06728|Aniline KLK1;ALB;CYP2E1 DB02153|3-Sulfinoalanine PAPOLA;aroH;GSR;PRDX2;def;FABP4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PRDX2;GSR GO:0043066| negative regulation of apoptotic process ALB;PRDX2 GO:0098869| GSR;ALB 28611:[DB06728 DB06481] DB06728|Aniline KLK1;ALB;CYP2E1 DB06481|Manitimus DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHODH GO:0042493| response to drug DHODH;CYP2E1 28612:[DB06728 DB09378] DB06728|Aniline KLK1;ALB;CYP2E1 DB09378|Fluprednisolone CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 28613:[DB06728 DB12026] DB06728|Aniline KLK1;ALB;CYP2E1 DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2E1 GO:0042493| response to drug ABCG2;ABCB1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1B3 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C8 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C8 28614:[DB06728 DB00215] DB06728|Aniline KLK1;ALB;CYP2E1 DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes CYP2E1 common pathways GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2B6;CYP2E1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6;CYP2D6;CYP2C19 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2;SLC6A4;SLC6A2;HTR2C;SLC6A3;ABCB1;ADRA1A GO:0055114| oxidation-reduction process CYP2B6;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2B6;CYP2C19 GO:0018910| benzene metabolic process CYP2E1 28615:[DB06728 DB00250] DB06728|Aniline KLK1;ALB;CYP2E1 DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes CYP2E1 common pathways GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2C18;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;MPO;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP3A4;CYP2E1;MPO;PTGS1;CYP2C18;FMO3;CYP2C9;CYP2C19;CYP2C8;CYP3A5 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;CYP2C9;CYP3A7;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8;CYP2C9 GO:0098869| PTGS1;PTGS2;ALB GO:0010193| response to ozone CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2C18;PTGS1;FMO3;CYP2C9;NAT2;CYP2C19;CYP2C8;CYP3A5 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 28616:[DB06728 DB07015] DB06728|Aniline KLK1;ALB;CYP2E1 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28617:[DB06728 DB00980] DB06728|Aniline KLK1;ALB;CYP2E1 DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2C19 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 28618:[DB06728 DB00167] DB06728|Aniline KLK1;ALB;CYP2E1 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process ACADSB;CYP2E1 28619:[DB06728 DB02459] DB06728|Aniline KLK1;ALB;CYP2E1 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways GO:0006508| proteolysis CFB;KLK1 28620:[DB06728 DB03845] DB06728|Aniline KLK1;ALB;CYP2E1 DB03845|P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate DTYMK common genes common pathways 28621:[DB06728 DB00241] DB06728|Aniline KLK1;ALB;CYP2E1 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 28622:[DB06728 DB02638] DB06728|Aniline KLK1;ALB;CYP2E1 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways 28623:[DB06728 DB05159] DB06728|Aniline KLK1;ALB;CYP2E1 DB05159|CCX915 CCR2 common genes common pathways 28624:[DB06728 DB06069] DB06728|Aniline KLK1;ALB;CYP2E1 DB06069|XMT-1001 TOP1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 28625:[DB06728 DB02074] DB06728|Aniline KLK1;ALB;CYP2E1 DB02074|Butenoic Acid FABP1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;FABP1 GO:0098869| ALB;FABP1 28626:[DB06728 DB03572] DB06728|Aniline KLK1;ALB;CYP2E1 DB03572|FR230513 ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0042493| response to drug ADA;CYP2E1 28627:[DB06728 DB14033] DB06728|Aniline KLK1;ALB;CYP2E1 DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 28628:[DB06728 DB05712] DB06728|Aniline KLK1;ALB;CYP2E1 DB05712|AZD-9684 CPB2 common genes common pathways GO:0006508| proteolysis KLK1;CPB2 GO:0042493| response to drug CPB2;CYP2E1 28629:[DB06728 DB00467] DB06728|Aniline KLK1;ALB;CYP2E1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 28630:[DB06728 DB07013] DB06728|Aniline KLK1;ALB;CYP2E1 DB07013|TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE MMP13 common genes common pathways GO:0006508| proteolysis MMP13;KLK1 GO:0044267| cellular protein metabolic process ALB;MMP13 28631:[DB06728 DB08837] DB06728|Aniline KLK1;ALB;CYP2E1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB 28632:[DB06728 DB00187] DB06728|Aniline KLK1;ALB;CYP2E1 DB00187|Esmolol ADRB1;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 28633:[DB06728 DB03336] DB06728|Aniline KLK1;ALB;CYP2E1 DB03336|BIA COMT common genes common pathways GO:0042493| response to drug CYP2E1;COMT 28634:[DB06728 DB12693] DB06728|Aniline KLK1;ALB;CYP2E1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 28635:[DB06728 DB06817] DB06728|Aniline KLK1;ALB;CYP2E1 DB06817|Raltegravir pol;UGT1A1 common genes common pathways GO:0042493| response to drug UGT1A1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 28636:[DB06728 DB04715] DB06728|Aniline KLK1;ALB;CYP2E1 DB04715|IMIDAZOPYRIDAZIN 1 PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 28637:[DB06728 DB09098] DB06728|Aniline KLK1;ALB;CYP2E1 DB09098|Somatrem GHR;IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process IGF1R;ALB 28638:[DB06728 DB09124] DB06728|Aniline KLK1;ALB;CYP2E1 DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes ALB common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 28639:[DB06728 DB06892] DB06728|Aniline KLK1;ALB;CYP2E1 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways 28640:[DB06728 DB05553] DB06728|Aniline KLK1;ALB;CYP2E1 DB05553|Regrelor P2RY12 common genes common pathways 28641:[DB06728 DB14031] DB06728|Aniline KLK1;ALB;CYP2E1 DB14031|Tretamine BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 28642:[DB06728 DB00013] DB06728|Aniline KLK1;ALB;CYP2E1 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0043066| negative regulation of apoptotic process SERPINB2;PLAUR;ALB GO:0002576| platelet degranulation PLG;ALB;SERPINE1 GO:0044267| cellular protein metabolic process PLG;ALB GO:0006508| proteolysis KLK1;ST14;PLG;PLAT;PLAU GO:0006898| receptor-mediated endocytosis LRP2;ALB 28643:[DB06728 DB05045] DB06728|Aniline KLK1;ALB;CYP2E1 DB05045|Obinepitide NPY4R;NPY2R common genes common pathways 28644:[DB06728 DB08672] DB06728|Aniline KLK1;ALB;CYP2E1 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 28645:[DB06728 DB07988] DB06728|Aniline KLK1;ALB;CYP2E1 DB07988|2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2YL)-UREIDO]-N-METHYL-3-PENTAFLUOROPHENYL-PROPIONAMIDE MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 28646:[DB06728 DB01863] DB06728|Aniline KLK1;ALB;CYP2E1 DB01863|Inositol 1,3,4,5-Tetrakisphosphate AKT1;PLEKHA4;BTK;DAPP1;ITPKA;CYTH2;CYTH3;PDPK1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKT1;ALB 28647:[DB06728 DB07176] DB06728|Aniline KLK1;ALB;CYP2E1 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 28648:[DB06728 DB08515] DB06728|Aniline KLK1;ALB;CYP2E1 DB08515|(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA6;PSMA7;PSMB1;PSMB2;PSMB3;PSMB4;PSMB5;PSMB6;PSMB7 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PSMB2 GO:0043687| post-translational protein modification PSMB5;PSMB7;PSMB3;PSMB1;PSMA5;PSMA4;PSMB4;PSMB2;PSMA6;PSMA7;PSMA1;PSMB6;PSMA3;ALB;PSMA2 GO:0006508| proteolysis PSMA2;PSMA3;PSMB6;PSMA7;PSMA1;PSMA6;KLK1;PSMB2;PSMA4;PSMB4;PSMB1;PSMB3;PSMA5;PSMB7;PSMB5 28649:[DB06728 DB00206] DB06728|Aniline KLK1;ALB;CYP2E1 DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A5 GO:0043066| negative regulation of apoptotic process BIRC5;ALB GO:0042493| response to drug CYP2E1;ABCB1;ABCC2 GO:0055114| oxidation-reduction process CYP3A5;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP2E1;CYP3A5 GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;SLCO2B1;ALB 28650:[DB06728 DB01222] DB06728|Aniline KLK1;ALB;CYP2E1 DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 28651:[DB06728 DB06446] DB06728|Aniline KLK1;ALB;CYP2E1 DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug HTR2C;CYP2E1;HTR2A 28652:[DB06728 DB09383] DB06728|Aniline KLK1;ALB;CYP2E1 DB09383|Meprednisone CYP3A4;ALB common genes ALB common pathways GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 28653:[DB06728 DB04648] DB06728|Aniline KLK1;ALB;CYP2E1 DB04648|S-propylamine-L-cysteine ARG1 common genes common pathways GO:0042493| response to drug ARG1;CYP2E1 28654:[DB06728 DB03306] DB06728|Aniline KLK1;ALB;CYP2E1 DB03306|RU78300 SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;SRC 28655:[DB06728 DB14009] DB06728|Aniline KLK1;ALB;CYP2E1 DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;GPX1;CAT GO:0001895| retina homeostasis SOD1;ALB GO:0045471| response to ethanol CAT;OPRM1;HMGCR;CYP2E1;SOD1;CNR1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5;CYP1B1;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;CYP2C9;CYP1A1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0098869| PTGS2;CAT;GPX1;PTGS1;GSR;ALB GO:0010193| response to ozone CYP2E1;CAT GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;HMGCR;PTGS2;SOD1;GPX1;CAT GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP1B1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;GPX1;CAT;HMGCR;PTGS2;CYP3A7;CYP1A2;SOD1;CYP3A4;CYP2E1;CYP1B1;CYP2D6;GSR;IDO1;CYP2C19;ALOX15;CYP3A5;CYP17A1;CRYZ;CYP2C9;CYP1A1 GO:0042493| response to drug ABCC1;SMPD1;TRPA1;PPARG;CYP1A1;ABCG2;PTGS2;CYP1A2;SOD1;HTR2A;CYP2E1;CAT GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 28656:[DB06728 DB00137] DB06728|Aniline KLK1;ALB;CYP2E1 DB00137|Lutein ALB common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB 28657:[DB06728 DB08954] DB06728|Aniline KLK1;ALB;CYP2E1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0045471| response to ethanol GRIN2B;CYP2E1;GRIN1 28658:[DB06728 DB07785] DB06728|Aniline KLK1;ALB;CYP2E1 DB07785|1-{(1R,2S)-2-HYDROXY-1-[2-(2-NAPHTHYLOXY)ETHYL]PROPYL}-1H-IMIDAZONE-4-CARBOXAMIDE ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0042493| response to drug ADA;CYP2E1 28659:[DB06728 DB01345] DB06728|Aniline KLK1;ALB;CYP2E1 DB01345|Potassium cation ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 28660:[DB06728 DB11338] DB06728|Aniline KLK1;ALB;CYP2E1 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0045471| response to ethanol CYP2E1;VCAM1 GO:0042493| response to drug COL1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;VCAM1 GO:0044267| cellular protein metabolic process ALB;CSF2RA 28661:[DB06728 DB06859] DB06728|Aniline KLK1;ALB;CYP2E1 DB06859|N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 28662:[DB06728 DB00505] DB06728|Aniline KLK1;ALB;CYP2E1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways 28663:[DB06728 DB08490] DB06728|Aniline KLK1;ALB;CYP2E1 DB08490|CTS-1027 MMP13 common genes common pathways GO:0044267| cellular protein metabolic process ALB;MMP13 GO:0006508| proteolysis KLK1;MMP13 28664:[DB06728 DB08775] DB06728|Aniline KLK1;ALB;CYP2E1 DB08775|Nα-[(Benzyloxy)carbonyl]-N-[(2S)-4-fluoro-3-oxo-2-butanyl]-L-tyrosinamide CTSF common genes common pathways GO:0006508| proteolysis CTSF;KLK1 28665:[DB06728 DB09499] DB06728|Aniline KLK1;ALB;CYP2E1 DB09499|Thiosulfuric acid TST common genes common pathways 28666:[DB06728 DB00166] DB06728|Aniline KLK1;ALB;CYP2E1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0043066| negative regulation of apoptotic process POR;ALB GO:0042493| response to drug CYP2E1;POR GO:0055114| oxidation-reduction process CYP2E1;POR GO:0006805| xenobiotic metabolic process CYP2E1;POR 28667:[DB06728 DB07550] DB06728|Aniline KLK1;ALB;CYP2E1 DB07550|2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 28668:[DB06728 DB04149] DB06728|Aniline KLK1;ALB;CYP2E1 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways 28669:[DB06728 DB11635] DB06728|Aniline KLK1;ALB;CYP2E1 DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0017144| drug metabolic process CYP4F2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process APOBR;NPC1L1;CYP2E1;CYP3A4;ABCA1 GO:0042493| response to drug NPC1L1;ABCB1;ABCG5;ABCG8;CYP2E1;ABCA1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP4F2 GO:0019373| epoxygenase P450 pathway CYP4F2;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB;SCARB1 GO:0006898| receptor-mediated endocytosis APOBR;ALB;SCARB1 GO:0006641| triglyceride metabolic process CYP2E1;APOBR GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 28670:[DB06728 DB08370] DB06728|Aniline KLK1;ALB;CYP2E1 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0098869| GSTP1;ALB 28671:[DB06728 DB00837] DB06728|Aniline KLK1;ALB;CYP2E1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways 28672:[DB06728 DB06785] DB06728|Aniline KLK1;ALB;CYP2E1 DB06785|Ganirelix GNRHR common genes common pathways 28673:[DB06728 DB11235] DB06728|Aniline KLK1;ALB;CYP2E1 DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 28674:[DB06728 DB13620] DB06728|Aniline KLK1;ALB;CYP2E1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0010243| response to organic nitrogen ATP4B;CYP2E1 GO:0042493| response to drug CYP2E1;ATP1A1 28675:[DB06728 DB05137] DB06728|Aniline KLK1;ALB;CYP2E1 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways 28676:[DB06728 DB14071] DB06728|Aniline KLK1;ALB;CYP2E1 DB14071|Desmethylsertraline ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 28677:[DB06728 DB03496] DB06728|Aniline KLK1;ALB;CYP2E1 DB03496|Alvocidib CDK2;CDK5;CDK9;CDK1;CDK6;EGFR;CDK4;CDK8;CDK7;PYGM;PYGB;PYGL;UGT1A1;ABCG2 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0043066| negative regulation of apoptotic process EGFR;ALB;CDK1 GO:0010243| response to organic nitrogen CYP2E1;CDK1 GO:0042493| response to drug ABCG2;UGT1A1;CYP2E1;CDK9;CDK1;CDK4 GO:0045471| response to ethanol UGT1A1;CDK1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 28678:[DB06728 DB04459] DB06728|Aniline KLK1;ALB;CYP2E1 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways GO:0006508| proteolysis KLK1;CFD GO:0002576| platelet degranulation CFD;ALB 28679:[DB06728 DB07101] DB06728|Aniline KLK1;ALB;CYP2E1 DB07101|PD-0325901 MAP2K1 common genes common pathways 28680:[DB06728 DB04754] DB06728|Aniline KLK1;ALB;CYP2E1 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug PNP;CYP2E1 28681:[DB06728 DB03695] DB06728|Aniline KLK1;ALB;CYP2E1 DB03695|Piritrexim DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 28682:[DB06728 DB00381] DB06728|Aniline KLK1;ALB;CYP2E1 DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2A6;CYP3A7;CYP3A5;CYP2D6;CYP2C8;CYP2C9;CYP1A1;CYP2B6 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4;CYP2B6;CYP2C9;CYP1A1;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2B6;CYP2C8;CYP2E1;CYP2A6 GO:0042493| response to drug CYP2E1;SMPD1;CYP1A1;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP2B6;CYP3A5;CYP2C8;CYP2D6;CYP3A7;CYP2E1;CYP3A4;CYP2A6 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A1;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C8;CYP3A7;CYP3A4;CYP2E1 28683:[DB06728 DB01979] DB06728|Aniline KLK1;ALB;CYP2E1 DB01979|Methyl alpha-D-mannoside MBL2 common genes common pathways GO:0006508| proteolysis KLK1;MBL2 28684:[DB06728 DB02845] DB06728|Aniline KLK1;ALB;CYP2E1 DB02845|Methylphosphinic Acid BCHE;ACHE;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 28685:[DB06728 DB01173] DB06728|Aniline KLK1;ALB;CYP2E1 DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes CYP2E1 common pathways GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6 GO:0045471| response to ethanol GRIN1;CYP2E1;GRIN3A GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6 GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2B6 GO:0042493| response to drug CYP2E1;CYP1A2;SLC6A2 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A2;CYP2E1 28686:[DB06728 DB00915] DB06728|Aniline KLK1;ALB;CYP2E1 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process MAOB;CYP2E1 GO:0042493| response to drug CYP2E1;MAOB;DRD2 GO:0045471| response to ethanol CYP2E1;DRD2;MAOB;GRIN3A 28687:[DB06728 DB02877] DB06728|Aniline KLK1;ALB;CYP2E1 DB02877|Arotinoid acid RARB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARB 28688:[DB06728 DB08454] DB06728|Aniline KLK1;ALB;CYP2E1 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CAMK1D 28689:[DB06728 DB07469] DB06728|Aniline KLK1;ALB;CYP2E1 DB07469|(3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 28690:[DB06728 DB06706] DB06728|Aniline KLK1;ALB;CYP2E1 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A 28691:[DB06728 DB00238] DB06728|Aniline KLK1;ALB;CYP2E1 DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C9;CYP1A2;CYP2A6;CYP2E1 GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2A6;CYP2C9;CYP2B6;CYP3A5;CYP2D6 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2D6;CYP3A5;CYP1A2;CYP2A6;CYP2E1;CYP3A4 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP2B6 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP3A5;CYP2B6;CYP2C9 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 28692:[DB06728 DB00214] DB06728|Aniline KLK1;ALB;CYP2E1 DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C8;CYP2C9 GO:0098869| PTGS1;ALB 28693:[DB06728 DB02373] DB06728|Aniline KLK1;ALB;CYP2E1 DB02373|Adenosine Monotungstate FHIT common genes common pathways 28694:[DB06728 DB11792] DB06728|Aniline KLK1;ALB;CYP2E1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2E1;CYP3A4;CYP3A7;CYP3A43 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 28695:[DB06728 DB03856] DB06728|Aniline KLK1;ALB;CYP2E1 DB03856|L-Eflornithine ODC1 common genes common pathways 28696:[DB06728 DB01120] DB06728|Aniline KLK1;ALB;CYP2E1 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes ALB common pathways GO:0098869| ALB GO:0017144| drug metabolic process CYP2C19;CYP2C9;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2C19;CYP2C9;CYP2E1 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation VEGFA;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1 GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0042493| response to drug CYP2E1;ABCC8 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28697:[DB06728 DB07339] DB06728|Aniline KLK1;ALB;CYP2E1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process NQO2;CYP2E1 GO:0055114| oxidation-reduction process NQO2;CYP2E1 28698:[DB06728 DB06471] DB06728|Aniline KLK1;ALB;CYP2E1 DB06471|Naxifylline ADORA1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADORA1 28699:[DB06728 DB00423] DB06728|Aniline KLK1;ALB;CYP2E1 DB00423|Methocarbamol CA1 common genes common pathways 28700:[DB06728 DB02776] DB06728|Aniline KLK1;ALB;CYP2E1 DB02776|1-Hexadecanosulfonic Acid FABP4 common genes common pathways 28701:[DB06728 DB06726] DB06728|Aniline KLK1;ALB;CYP2E1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 28702:[DB06728 DB01933] DB06728|Aniline KLK1;ALB;CYP2E1 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways 28703:[DB06728 DB08365] DB06728|Aniline KLK1;ALB;CYP2E1 DB08365|8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide WEE1 common genes common pathways 28704:[DB06728 DB01748] DB06728|Aniline KLK1;ALB;CYP2E1 DB01748|N-Benzyl-4-Sulfamoyl-Benzamide CA2 common genes common pathways 28705:[DB06728 DB07994] DB06728|Aniline KLK1;ALB;CYP2E1 DB07994|N~3~-[5-(1H-INDOL-6-YL)-2-(PYRIDIN-2-YLMETHOXY)BENZYL]PYRIDINE-2,3-DIAMINE BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process BACE1;ALB 28706:[DB06728 DB03606] DB06728|Aniline KLK1;ALB;CYP2E1 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways 28707:[DB06728 DB07217] DB06728|Aniline KLK1;ALB;CYP2E1 DB07217|N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide MAPK10 common genes common pathways 28708:[DB06728 DB11477] DB06728|Aniline KLK1;ALB;CYP2E1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways 28709:[DB06728 DB00244] DB06728|Aniline KLK1;ALB;CYP2E1 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0043066| negative regulation of apoptotic process MPO;IKBKB;PTGS2;ALB GO:0042493| response to drug PPARG;PTGS2;CYP2E1;CHUK GO:0055114| oxidation-reduction process PTGS2;CYP2E1;MPO;PTGS1;ALOX5 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0098869| ALB;PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 28710:[DB06728 DB03977] DB06728|Aniline KLK1;ALB;CYP2E1 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYCS GO:0002576| platelet degranulation ALB;CALM1 28711:[DB06728 DB11274] DB06728|Aniline KLK1;ALB;CYP2E1 DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug DRD3;DRD2;CYP2E1;DRD1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 28712:[DB06728 DB08418] DB06728|Aniline KLK1;ALB;CYP2E1 DB08418|(4aS,4bR,10bS,12aS)-12a-methyl-1,3-dioxo-2-(pyridin-3-ylmethyl)-1,2,3,4,4a,4b,5,6,10b,11,12,12a-dodecahydronaphtho[2,1-f]isoquinolin-8-yl sulfamate CA2 common genes common pathways 28713:[DB06728 DB03401] DB06728|Aniline KLK1;ALB;CYP2E1 DB03401|1D-myo-inositol 1,4,5-trisphosphate CYTH2;EPN1;PLCD1;RDX;SPTBN1;ITPR1;ITPKA common genes common pathways 28714:[DB06728 DB00070] DB06728|Aniline KLK1;ALB;CYP2E1 DB00070|Hyaluronidase TGFB1;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0042493| response to drug CYP2E1;TGFB1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB;TGFB1 GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28715:[DB06728 DB00274] DB06728|Aniline KLK1;ALB;CYP2E1 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB 28716:[DB06728 DB01352] DB06728|Aniline KLK1;ALB;CYP2E1 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 28717:[DB06728 DB02255] DB06728|Aniline KLK1;ALB;CYP2E1 DB02255|GM6001 ADAM28;ACAN common genes common pathways GO:0006508| proteolysis ADAM28;KLK1;ACAN 28718:[DB06728 DB06468] DB06728|Aniline KLK1;ALB;CYP2E1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SLC9A1;MPO GO:0055114| oxidation-reduction process MPO;CYP2E1 28719:[DB06728 DB07638] DB06728|Aniline KLK1;ALB;CYP2E1 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways 28720:[DB06728 DB06833] DB06728|Aniline KLK1;ALB;CYP2E1 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways 28721:[DB06728 DB13932] DB06728|Aniline KLK1;ALB;CYP2E1 DB13932|Voretigene Neparvovec RPE65 common genes common pathways GO:0001895| retina homeostasis ALB;RPE65 GO:0055114| oxidation-reduction process RPE65;CYP2E1 28722:[DB06728 DB07967] DB06728|Aniline KLK1;ALB;CYP2E1 DB07967|9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE CTSK common genes common pathways GO:0006508| proteolysis KLK1;CTSK 28723:[DB06728 DB06358] DB06728|Aniline KLK1;ALB;CYP2E1 DB06358|Iclaprim DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP2E1 28724:[DB06728 DB14185] DB06728|Aniline KLK1;ALB;CYP2E1 DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug DRD1;HTR2A;CYP2E1;HTR2C;HTR1B;ADRA1A;DRD2;DRD3 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP3A7;CYP3A4;CYP2E1 GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2D6;CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol DRD3;HTR1B;DRD2;HTR3A;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 28725:[DB06728 DB02306] DB06728|Aniline KLK1;ALB;CYP2E1 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 28726:[DB06728 DB09276] DB06728|Aniline KLK1;ALB;CYP2E1 DB09276|Sodium aurothiomalate UGT1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0042493| response to drug UGT1A1;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1 GO:0017144| drug metabolic process UGT1A1;CYP2E1 28727:[DB06728 DB00689] DB06728|Aniline KLK1;ALB;CYP2E1 DB00689|Cephaloglycin SLC22A5 common genes common pathways 28728:[DB06728 DB08089] DB06728|Aniline KLK1;ALB;CYP2E1 DB08089|LGD-2226 AR common genes common pathways 28729:[DB06728 DB01044] DB06728|Aniline KLK1;ALB;CYP2E1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes ALB common pathways GO:0098869| ALB GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug CYP2E1;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 28730:[DB06728 DB06073] DB06728|Aniline KLK1;ALB;CYP2E1 DB06073|CTS-21166 BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis KLK1;BACE1 28731:[DB06728 DB04012] DB06728|Aniline KLK1;ALB;CYP2E1 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways 28732:[DB06728 DB02557] DB06728|Aniline KLK1;ALB;CYP2E1 DB02557|Phosphoramidon MME;KEL common genes common pathways GO:0006508| proteolysis KLK1;KEL;MME 28733:[DB06728 DB00759] DB06728|Aniline KLK1;ALB;CYP2E1 DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes ALB common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLC22A6;SLC22A11;SLC22A7;SLC22A8 GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB;PRNP GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28734:[DB06728 DB07110] DB06728|Aniline KLK1;ALB;CYP2E1 DB07110|4-(4-FLUOROBENZYL)PIPERIDINE BACE1 common genes common pathways GO:0006508| proteolysis BACE1;KLK1 GO:0044267| cellular protein metabolic process ALB;BACE1 28735:[DB06728 DB04281] DB06728|Aniline KLK1;ALB;CYP2E1 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHODH GO:0042493| response to drug DHODH;CYP2E1 28736:[DB06728 DB05171] DB06728|Aniline KLK1;ALB;CYP2E1 DB05171|E-2012 APH1A;PSENEN common genes common pathways 28737:[DB06728 DB03332] DB06728|Aniline KLK1;ALB;CYP2E1 DB03332|5,6-Cyclic-Tetrahydropteridine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 28738:[DB06728 DB04894] DB06728|Aniline KLK1;ALB;CYP2E1 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol TACR1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0010193| response to ozone CYP2E1;TACR1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 28739:[DB06728 DB00772] DB06728|Aniline KLK1;ALB;CYP2E1 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2B6 GO:0055114| oxidation-reduction process CYP2B6;CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2;BCHE GO:0017144| drug metabolic process CYP2B6;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 28740:[DB06728 DB03760] DB06728|Aniline KLK1;ALB;CYP2E1 DB03760|Dihydrolipoic Acid GCSH;DLAT;PDK3 common genes common pathways 28741:[DB06728 DB07135] DB06728|Aniline KLK1;ALB;CYP2E1 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 28742:[DB06728 DB01206] DB06728|Aniline KLK1;ALB;CYP2E1 DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 28743:[DB06728 DB09079] DB06728|Aniline KLK1;ALB;CYP2E1 DB09079|Nintedanib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FLT3;LCK;LYN;SRC;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0002576| platelet degranulation LYN;ALB GO:0043066| negative regulation of apoptotic process FLT4;ALB;KDR;SRC GO:0042493| response to drug ABCB1;LCK;LYN;SRC;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0010243| response to organic nitrogen CYP2E1;FLT3 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;FGFR2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28744:[DB06728 DB12001] DB06728|Aniline KLK1;ALB;CYP2E1 DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug OTC;CDK4;CYP2E1;ABCB1;ABCG2 GO:0002576| platelet degranulation ALB;ORM1;ORM2 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB 28745:[DB06728 DB07525] DB06728|Aniline KLK1;ALB;CYP2E1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways 28746:[DB06728 DB06993] DB06728|Aniline KLK1;ALB;CYP2E1 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28747:[DB06728 DB05667] DB06728|Aniline KLK1;ALB;CYP2E1 DB05667|Levoketoconazole CYP11B1;CYP51A1 common genes common pathways GO:0008202| steroid metabolic process CYP11B1;CYP51A1;CYP2E1 GO:0055114| oxidation-reduction process CYP51A1;CYP11B1;CYP2E1 28748:[DB06728 DB06184] DB06728|Aniline KLK1;ALB;CYP2E1 DB06184|AEG35156 XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process XIAP;ALB 28749:[DB06728 DB08953] DB06728|Aniline KLK1;ALB;CYP2E1 DB08953|Indalpine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28750:[DB06728 DB02919] DB06728|Aniline KLK1;ALB;CYP2E1 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 28751:[DB06728 DB01131] DB06728|Aniline KLK1;ALB;CYP2E1 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9;DHFR GO:0042493| response to drug CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 28752:[DB06728 DB07141] DB06728|Aniline KLK1;ALB;CYP2E1 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 28753:[DB06728 DB00421] DB06728|Aniline KLK1;ALB;CYP2E1 DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;NR1I2;CYP2E1 GO:0042493| response to drug ABCB1;ABCC2;CYP2E1;SRD5A2;SRD5A1 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;SRD5A2;SRD5A3;CYP11B2;CYP11B1;SRD5A1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;ALB GO:0008202| steroid metabolic process SRD5A1;SRD5A2;CYP2E1;CYP11B1;CYP11B2;CYP2C8;NR1I2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB;SRD5A1 GO:0017144| drug metabolic process CYP2E1;CYP2C8 28754:[DB06728 DB05078] DB06728|Aniline KLK1;ALB;CYP2E1 DB05078|AER001 IL4R;IL13RA2 common genes common pathways 28755:[DB06728 DB00572] DB06728|Aniline KLK1;ALB;CYP2E1 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0045471| response to ethanol CHRNB2;CYP2E1 28756:[DB06728 DB05332] DB06728|Aniline KLK1;ALB;CYP2E1 DB05332|Romiplostim MPL common genes common pathways 28757:[DB06728 DB05339] DB06728|Aniline KLK1;ALB;CYP2E1 DB05339|MN-305 HTR1A common genes common pathways 28758:[DB06728 DB00598] DB06728|Aniline KLK1;ALB;CYP2E1 DB00598|Labetalol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP2C19 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0042493| response to drug ADRA1A;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 28759:[DB06728 DB07036] DB06728|Aniline KLK1;ALB;CYP2E1 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways 28760:[DB06728 DB00415] DB06728|Aniline KLK1;ALB;CYP2E1 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process TEK;ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 28761:[DB06728 DB00110] DB06728|Aniline KLK1;ALB;CYP2E1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006508| proteolysis C1QB;C1R;KLK1;C1QA;C1QC GO:0006898| receptor-mediated endocytosis FCGR1A;ALB;FCGR2B 28762:[DB06728 DB03084] DB06728|Aniline KLK1;ALB;CYP2E1 DB03084|Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine MAPK10 common genes common pathways 28763:[DB06728 DB00312] DB06728|Aniline KLK1;ALB;CYP2E1 DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0045471| response to ethanol GRIN3A;CYP2E1;GRIN2B;GRIN1;GRIN2A GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19;NR1I2 GO:0008202| steroid metabolic process CYP2C19;NR1I2;CYP2A6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C19;CYP3A4;CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP2A6;CYP2E1;CYP3A4;CYP2C19 GO:0042493| response to drug GRIN2A;GABRG3;CYP2E1 28764:[DB06728 DB01094] DB06728|Aniline KLK1;ALB;CYP2E1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2;SOAT1;SOAT2 GO:0042493| response to drug CYP1A2;CYP2E1;ABCG2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 28765:[DB06728 DB05139] DB06728|Aniline KLK1;ALB;CYP2E1 DB05139|CR002 PDGFD common genes common pathways 28766:[DB06728 DB11275] DB06728|Aniline KLK1;ALB;CYP2E1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0042493| response to drug DRD1;CYP2E1;DRD2;DRD3 GO:0045471| response to ethanol CYP2E1;DRD2;DRD3 28767:[DB06728 DB00650] DB06728|Aniline KLK1;ALB;CYP2E1 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 28768:[DB06728 DB08980] DB06728|Aniline KLK1;ALB;CYP2E1 DB08980|Fendiline CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 28769:[DB06728 DB09026] DB06728|Aniline KLK1;ALB;CYP2E1 DB09026|Aliskiren REN;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug CYP2E1;REN GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 28770:[DB06728 DB07028] DB06728|Aniline KLK1;ALB;CYP2E1 DB07028|(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 28771:[DB06728 DB04738] DB06728|Aniline KLK1;ALB;CYP2E1 DB04738|Motuporin PPP1CC common genes common pathways 28772:[DB06728 DB04444] DB06728|Aniline KLK1;ALB;CYP2E1 DB04444|Tetrafluoroaluminate Ion argB;GNAI1;ATP2A1;GNAT1;CMPK1;MYH11;MYH14;recA;rbsK common genes common pathways GO:0051659| maintenance of mitochondrion location ATP2A1;ALB 28773:[DB06728 DB01247] DB06728|Aniline KLK1;ALB;CYP2E1 DB01247|Isocarboxazid MAOA;MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0042493| response to drug CYP2E1;MAOB GO:0055114| oxidation-reduction process MAOA;CYP2E1;MAOB 28774:[DB06728 DB09183] DB06728|Aniline KLK1;ALB;CYP2E1 DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0042493| response to drug ABCG2;ABCB1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 28775:[DB06728 DB08449] DB06728|Aniline KLK1;ALB;CYP2E1 DB08449|2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 28776:[DB06728 DB07542] DB06728|Aniline KLK1;ALB;CYP2E1 DB07542|5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOBUTYL-HEXANOIC ACID CTSD common genes common pathways GO:0006508| proteolysis CTSD;KLK1 28777:[DB06728 DB05001] DB06728|Aniline KLK1;ALB;CYP2E1 DB05001|PSN9301 DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28778:[DB06728 DB11973] DB06728|Aniline KLK1;ALB;CYP2E1 DB11973|Tesevatinib EGF;EPHB4;ERBB2 common genes common pathways GO:0002576| platelet degranulation ALB;EGF 28779:[DB06728 DB00111] DB06728|Aniline KLK1;ALB;CYP2E1 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FCGR1A;FCGR2B GO:0006508| proteolysis C1QC;KLK1;C1QA;C1QB;C1R GO:0043066| negative regulation of apoptotic process IL2RB;ALB 28780:[DB06728 DB06857] DB06728|Aniline KLK1;ALB;CYP2E1 DB06857|N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 28781:[DB06728 DB01030] DB06728|Aniline KLK1;ALB;CYP2E1 DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;ABCB1;ABCG2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 28782:[DB06728 DB13933] DB06728|Aniline KLK1;ALB;CYP2E1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0006508| proteolysis KLK1;F7;F10 GO:0002576| platelet degranulation F8;ALB GO:0055114| oxidation-reduction process CYP2E1;F8 28783:[DB06728 DB07325] DB06728|Aniline KLK1;ALB;CYP2E1 DB07325|N-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)METHYL]-3-{[(E)-(2-OXODIHYDROFURAN-3(2H)-YLIDENE)METHYL]AMINO}BENZENESULFONAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 28784:[DB06728 DB04796] DB06728|Aniline KLK1;ALB;CYP2E1 DB04796|Inecalcitol VDR common genes common pathways 28785:[DB06728 DB02930] DB06728|Aniline KLK1;ALB;CYP2E1 DB02930|Adenosine 5'-[γ-thio]triphosphate BST1;SYN1;BCKDK;PFKFB1;PMS2;recA;recA;recA;recQ common genes common pathways GO:0042493| response to drug PMS2;CYP2E1 28786:[DB06728 DB13948] DB06728|Aniline KLK1;ALB;CYP2E1 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1 28787:[DB06728 DB08574] DB06728|Aniline KLK1;ALB;CYP2E1 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 28788:[DB06728 DB01466] DB06728|Aniline KLK1;ALB;CYP2E1 DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2D6;POR;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2B6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2B6 GO:0043066| negative regulation of apoptotic process POR;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6 GO:0055114| oxidation-reduction process CYP2B6;CYP2D6;POR;CYP3A4;CYP2E1 GO:0042493| response to drug POR;CYP2E1 28789:[DB06728 DB00568] DB06728|Aniline KLK1;ALB;CYP2E1 DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2;DRD1;CYP1A1;DRD2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP1A1;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP1A2;CYP2B6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2A6;CYP1A2;CYP2C9;CYP1A1;CYP2B6;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C9;CYP1A1;CYP2B6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP1A1 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2B6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 28790:[DB06728 DB07768] DB06728|Aniline KLK1;ALB;CYP2E1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;AKR1C1 GO:0055114| oxidation-reduction process AKR1C1;CYP2E1;AKR1C2 GO:0008202| steroid metabolic process AKR1C2;CYP2E1 GO:0015721| bile acid and bile salt transport AKR1C1;ALB 28791:[DB06728 DB05482] DB06728|Aniline KLK1;ALB;CYP2E1 DB05482|7-ethyl-10-hydroxycamptothecin TOP1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug TOP1;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 28792:[DB06728 DB01053] DB06728|Aniline KLK1;ALB;CYP2E1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1B1 GO:0043252| sodium-independent organic anion transport SLC22A6;SLCO2B1;ALB;SLCO3A1;SLC22A8;SLCO1B1;SLC22A11;SLCO4A1 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 28793:[DB06728 DB00350] DB06728|Aniline KLK1;ALB;CYP2E1 DB00350|Minoxidil KCNJ1;PTGS1;REN;UGT1A1 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0006508| proteolysis REN;KLK1 GO:0017144| drug metabolic process CYP2E1;UGT1A1 GO:0098869| ALB;PTGS1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS1 GO:0042493| response to drug REN;UGT1A1;CYP2E1 28794:[DB06728 DB06830] DB06728|Aniline KLK1;ALB;CYP2E1 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 28795:[DB06728 DB03247] DB06728|Aniline KLK1;ALB;CYP2E1 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;POR GO:0042493| response to drug POR;DHODH;CYP2E1 GO:0055114| oxidation-reduction process POR;BLVRB;NOS1;DPYD;DHODH;PNPO;HAO2;HAO1;CYP2E1 GO:0043066| negative regulation of apoptotic process POR;ALB 28796:[DB06728 DB03907] DB06728|Aniline KLK1;ALB;CYP2E1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0042493| response to drug COMT;CYP2E1 28797:[DB06728 DB01085] DB06728|Aniline KLK1;ALB;CYP2E1 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28798:[DB06728 DB06354] DB06728|Aniline KLK1;ALB;CYP2E1 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways 28799:[DB06728 DB12773] DB06728|Aniline KLK1;ALB;CYP2E1 DB12773|Sifalimumab IFNA2 common genes common pathways 28800:[DB06728 DB00227] DB06728|Aniline KLK1;ALB;CYP2E1 DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0045471| response to ethanol UGT1A1;HMGCR;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP2C8;CYP3A7;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1A2 GO:0008202| steroid metabolic process UGT2B7;HMGCR;CYP3A7;CYP2E1;CYP3A4;CYP2C8;CYP2D6;CYP3A5;UGT1A1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP3A4;UGT1A3;CYP2C9;UGT1A1;CYP2C8;CYP2D6 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1B1;SLCO1A2;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 GO:0043066| negative regulation of apoptotic process HDAC2;HMGCR;ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A7;HMGCR;CYP2C9;CYP3A5;CYP2C8;CYP2D6 GO:0042493| response to drug ABCC2;ABCB1;UGT1A1;HDAC2;CYP2E1 28801:[DB06728 DB04893] DB06728|Aniline KLK1;ALB;CYP2E1 DB04893|AZD3409 FNTB;FNTA common genes common pathways 28802:[DB06728 DB07068] DB06728|Aniline KLK1;ALB;CYP2E1 DB07068|(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID PTPRB common genes common pathways 28803:[DB06728 DB04521] DB06728|Aniline KLK1;ALB;CYP2E1 DB04521|GSHNA GSTA3 common genes common pathways 28804:[DB06728 DB07400] DB06728|Aniline KLK1;ALB;CYP2E1 DB07400|1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 28805:[DB06728 DB04756] DB06728|Aniline KLK1;ALB;CYP2E1 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 28806:[DB06728 DB02018] DB06728|Aniline KLK1;ALB;CYP2E1 DB02018|Amido Phenyl Pyruvic Acid TPSB2 common genes common pathways GO:0006508| proteolysis TPSB2;KLK1 28807:[DB06728 DB01645] DB06728|Aniline KLK1;ALB;CYP2E1 DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes common pathways GO:0045471| response to ethanol PTK2B;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;NR1I2;CYP2C8;CYP1B1 GO:0044267| cellular protein metabolic process TTR;ALB GO:0015721| bile acid and bile salt transport NCOA1;SLCO1B1;NCOA2;SLCO2B1;ALB GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB;SLCO2B1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C8;CYP1B1;NR1I2;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP1B1;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;ABCC1;ABCB1;ABCG2;PTK2B GO:0010243| response to organic nitrogen PTK2B;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1B1;CYP2C8;CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process AKT1;ALB;PTK2B 28808:[DB06728 DB11731] DB06728|Aniline KLK1;ALB;CYP2E1 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 28809:[DB06728 DB04753] DB06728|Aniline KLK1;ALB;CYP2E1 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug CYP2E1;PNP 28810:[DB06728 DB07522] DB06728|Aniline KLK1;ALB;CYP2E1 DB07522|N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis KLK1;F2 28811:[DB06728 DB01033] DB06728|Aniline KLK1;ALB;CYP2E1 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0042493| response to drug CYP2E1;PPAT;ABCC4 GO:0055114| oxidation-reduction process IMPDH1;AOX1;XDH;CYP2E1;IMPDH2;ABCC4 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0002576| platelet degranulation ABCC4;ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 GO:0017144| drug metabolic process AOX1;CYP2E1 28812:[DB06728 DB02264] DB06728|Aniline KLK1;ALB;CYP2E1 DB02264|O2-Sulfo-Glucuronic Acid FGF1;HGF;HS3ST3A1 common genes common pathways GO:0006508| proteolysis KLK1;HGF GO:0002576| platelet degranulation ALB;HGF GO:0043066| negative regulation of apoptotic process ALB;HGF 28813:[DB06728 DB05883] DB06728|Aniline KLK1;ALB;CYP2E1 DB05883|ABX-PTH PTH common genes common pathways GO:0042493| response to drug PTH;CYP2E1 GO:0045471| response to ethanol CYP2E1;PTH 28814:[DB06728 DB08841] DB06728|Aniline KLK1;ALB;CYP2E1 DB08841|Tyramine SLC22A3 common genes common pathways 28815:[DB06728 DB08814] DB06728|Aniline KLK1;ALB;CYP2E1 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes ALB common pathways GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB;PTGS1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB;NFKB1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;PTGS1;NOS2 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 28816:[DB06728 DB00365] DB06728|Aniline KLK1;ALB;CYP2E1 DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2;ABCC2;ABCB1;ABCC1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1 28817:[DB06728 DB07443] DB06728|Aniline KLK1;ALB;CYP2E1 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHODH GO:0042493| response to drug CYP2E1;DHODH 28818:[DB06728 DB11619] DB06728|Aniline KLK1;ALB;CYP2E1 DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 28819:[DB06728 DB07032] DB06728|Aniline KLK1;ALB;CYP2E1 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways 28820:[DB06728 DB09272] DB06728|Aniline KLK1;ALB;CYP2E1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1B1;ALB GO:0042493| response to drug ABCC2;CYP2E1 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 28821:[DB06728 DB07625] DB06728|Aniline KLK1;ALB;CYP2E1 DB07625|4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 28822:[DB06728 DB00024] DB06728|Aniline KLK1;ALB;CYP2E1 DB00024|Thyrotropin alfa TSHR common genes common pathways 28823:[DB06728 DB04871] DB06728|Aniline KLK1;ALB;CYP2E1 DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2B6;CYP1A1;CYP2A6;CYP2E1;FMO1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP2B6;CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP2A6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2B6;CYP1A1;CYP1A2;CYP2A6;FMO1;CYP2E1;CYP3A4 GO:0042493| response to drug CYP1A1;HTR2C;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2A6;CYP1A1;CYP2B6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;FMO1;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2B6 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP1A1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 28824:[DB06728 DB05814] DB06728|Aniline KLK1;ALB;CYP2E1 DB05814|GPI-1485 FKBP1A;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28825:[DB06728 DB09201] DB06728|Aniline KLK1;ALB;CYP2E1 DB09201|Ciglitazone PPARG;CYP3A4;CYP2C8 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;PPARG GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 28826:[DB06728 DB03616] DB06728|Aniline KLK1;ALB;CYP2E1 DB03616|Kabiramide C ACTA1 common genes common pathways 28827:[DB06728 DB04232] DB06728|Aniline KLK1;ALB;CYP2E1 DB04232|N-Hydroxy-1-(4-Methoxyphenyl)Sulfonyl-4-Benzyloxycarbonyl-Piperazine-2-Carboxamide MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 28828:[DB06728 DB00294] DB06728|Aniline KLK1;ALB;CYP2E1 DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 28829:[DB06728 DB00657] DB06728|Aniline KLK1;ALB;CYP2E1 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0045471| response to ethanol CYP2E1;CHRNB2 28830:[DB06728 DB08844] DB06728|Aniline KLK1;ALB;CYP2E1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLC22A6 28831:[DB06728 DB07557] DB06728|Aniline KLK1;ALB;CYP2E1 DB07557|(5BETA)-PREGNANE-3,20-DIONE NCOA1;RXRA;NR1I3;AKR1D1 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA1;RXRA;ALB GO:0008202| steroid metabolic process CYP2E1;AKR1D1 GO:0055114| oxidation-reduction process AKR1D1;CYP2E1 28832:[DB06728 DB01375] DB06728|Aniline KLK1;ALB;CYP2E1 DB01375|Aluminium monostearate TNNC1;VDAC1;VDAC2;VDAC3 common genes common pathways 28833:[DB06728 DB01182] DB06728|Aniline KLK1;ALB;CYP2E1 DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1 28834:[DB06728 DB01104] DB06728|Aniline KLK1;ALB;CYP2E1 DB01104|Sertraline SLC6A4;SLC6A3;PGRMC1;SIGMAR1;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP2B6;MAOB;MAOA;CYP2B;ALB;ABCB1 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9;CYP2B6 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2D6;CYP2C19 GO:0042493| response to drug MAOB;ABCB1;SLC6A3;CYP2E1;SLC6A4 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;MAOB;CYP2D6;CYP2C19;CYP3A4;CYP2E1;MAOA GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C9;CYP2C19 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;SLC6A3;MAOB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2B6;CYP2C9 28835:[DB06728 DB07945] DB06728|Aniline KLK1;ALB;CYP2E1 DB07945|5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid FABP4 common genes common pathways 28836:[DB06728 DB09110] DB06728|Aniline KLK1;ALB;CYP2E1 DB09110|Coenzyme M GSR common genes common pathways GO:0055114| oxidation-reduction process GSR;CYP2E1 GO:0098869| GSR;ALB 28837:[DB06728 DB00810] DB06728|Aniline KLK1;ALB;CYP2E1 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 28838:[DB06728 DB08382] DB06728|Aniline KLK1;ALB;CYP2E1 DB08382|Gosogliptin DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 28839:[DB06728 DB01018] DB06728|Aniline KLK1;ALB;CYP2E1 DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 28840:[DB06728 DB09460] DB06728|Aniline KLK1;ALB;CYP2E1 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways GO:0042493| response to drug CYP2E1;CA9 28841:[DB06728 DB01405] DB06728|Aniline KLK1;ALB;CYP2E1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 28842:[DB06728 DB02613] DB06728|Aniline KLK1;ALB;CYP2E1 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0006641| triglyceride metabolic process PNLIPRP2;CYP2E1 GO:0042493| response to drug CYP2E1;DHODH GO:0055114| oxidation-reduction process DHODH;CYP2E1 28843:[DB06728 DB07324] DB06728|Aniline KLK1;ALB;CYP2E1 DB07324|3-({2-[(2-AMINO-6-METHYLPYRIMIDIN-4-YL)ETHYNYL]BENZYL}AMINO)-1,3-OXAZOL-2(3H)-ONE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 28844:[DB06728 DB13873] DB06728|Aniline KLK1;ALB;CYP2E1 DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;NR1I2 GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0042493| response to drug CYP2E1;PPARG GO:0008202| steroid metabolic process CYP2E1;NR1I2 28845:[DB06728 DB05361] DB06728|Aniline KLK1;ALB;CYP2E1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0043687| post-translational protein modification ALB;SERPINC1 GO:0044267| cellular protein metabolic process SERPINC1;ALB 28846:[DB06728 DB08875] DB06728|Aniline KLK1;ALB;CYP2E1 DB08875|Cabozantinib MET;KDR;RET;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0042493| response to drug RET;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;KDR GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 28847:[DB06728 DB01409] DB06728|Aniline KLK1;ALB;CYP2E1 DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 28848:[DB06728 DB00812] DB06728|Aniline KLK1;ALB;CYP2E1 DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2E1;PTGS1 GO:0043252| sodium-independent organic anion transport SLC22A11;SLC22A8;ALB;SLC22A6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0098869| ALB;PTGS2;PTGS1 GO:0017144| drug metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGIS;CYP2C9;PTGS1;PTGS2;CYP2E1;CYP3A4 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 28849:[DB06728 DB08784] DB06728|Aniline KLK1;ALB;CYP2E1 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 28850:[DB06728 DB02285] DB06728|Aniline KLK1;ALB;CYP2E1 DB02285|Protoporphyrin FTL common genes common pathways 28851:[DB06728 DB00038] DB06728|Aniline KLK1;ALB;CYP2E1 DB00038|Oprelvekin IL11RA common genes common pathways 28852:[DB06728 DB07249] DB06728|Aniline KLK1;ALB;CYP2E1 DB07249|N-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine EPHB4 common genes common pathways 28853:[DB06728 DB00512] DB06728|Aniline KLK1;ALB;CYP2E1 DB00512|Vancomycin ALB;ORM1;ORM2 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB;ORM1;ORM2 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB 28854:[DB06728 DB04448] DB06728|Aniline KLK1;ALB;CYP2E1 DB04448|2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;CYP2E1 28855:[DB06728 DB00865] DB06728|Aniline KLK1;ALB;CYP2E1 DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0017144| drug metabolic process CYP2B6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2B6 GO:0042493| response to drug ADRA1A;POR;SLC6A3;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;POR;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;POR GO:0006805| xenobiotic metabolic process POR;CYP2B6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;SLC6A3 28856:[DB06728 DB06231] DB06728|Aniline KLK1;ALB;CYP2E1 DB06231|Caldaret SLC8A1 common genes common pathways GO:0042493| response to drug SLC8A1;CYP2E1 28857:[DB06728 DB00733] DB06728|Aniline KLK1;ALB;CYP2E1 DB00733|Pralidoxime ACHE;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 28858:[DB06728 DB03189] DB06728|Aniline KLK1;ALB;CYP2E1 DB03189|Cu-Cyclam LYZ common genes common pathways GO:0044267| cellular protein metabolic process LYZ;ALB GO:0001895| retina homeostasis ALB;LYZ 28859:[DB06728 DB00160] DB06728|Aniline KLK1;ALB;CYP2E1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0042493| response to drug CYP2E1;ABAT GO:0045471| response to ethanol CYP2E1;ABAT 28860:[DB06728 DB04246] DB06728|Aniline KLK1;ALB;CYP2E1 DB04246|CRA_23653 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 28861:[DB06728 DB00764] DB06728|Aniline KLK1;ALB;CYP2E1 DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 28862:[DB06728 DB03020] DB06728|Aniline KLK1;ALB;CYP2E1 DB03020|5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1C 28863:[DB06728 DB00596] DB06728|Aniline KLK1;ALB;CYP2E1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways 28864:[DB06728 DB07008] DB06728|Aniline KLK1;ALB;CYP2E1 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 28865:[DB06728 DB00694] DB06728|Aniline KLK1;ALB;CYP2E1 DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0042493| response to drug POR;ABCB1;ABCG2;ABCC2;ABCC6;ABCC1;CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP3A5;CYP1B1;POR;CYP2E1;CYP3A4;XDH GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1;CYP1B1 GO:0043066| negative regulation of apoptotic process ALB;POR GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A1;CYP3A5;CYP1B1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP1B1;POR;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 28866:[DB06728 DB00094] DB06728|Aniline KLK1;ALB;CYP2E1 DB00094|Urofollitropin FSHR common genes common pathways 28867:[DB06728 DB00189] DB06728|Aniline KLK1;ALB;CYP2E1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug CYP2E1;GABRG3 28868:[DB06728 DB09395] DB06728|Aniline KLK1;ALB;CYP2E1 DB09395|Sodium acetate ACSS2 common genes common pathways 28869:[DB06728 DB11639] DB06728|Aniline KLK1;ALB;CYP2E1 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways GO:0009267| cellular response to starvation ALB;BMPR2 28870:[DB06728 DB11075] DB06728|Aniline KLK1;ALB;CYP2E1 DB11075|Hypromellose EPCAM common genes common pathways 28871:[DB06728 DB01366] DB06728|Aniline KLK1;ALB;CYP2E1 DB01366|Procaterol ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB 28872:[DB06728 DB00385] DB06728|Aniline KLK1;ALB;CYP2E1 DB00385|Valrubicin TOP2A common genes common pathways 28873:[DB06728 DB14596] DB06728|Aniline KLK1;ALB;CYP2E1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 28874:[DB06728 DB01656] DB06728|Aniline KLK1;ALB;CYP2E1 DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 28875:[DB06728 DB01440] DB06728|Aniline KLK1;ALB;CYP2E1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 28876:[DB06728 DB00920] DB06728|Aniline KLK1;ALB;CYP2E1 DB00920|Ketotifen HRH1;PGD common genes common pathways GO:0055114| oxidation-reduction process PGD;CYP2E1 28877:[DB06728 DB04207] DB06728|Aniline KLK1;ALB;CYP2E1 DB04207|N-(5-Amino-5-Carboxypentyl)Glutamic Acid AASS common genes common pathways GO:0055114| oxidation-reduction process AASS;CYP2E1 28878:[DB06728 DB07105] DB06728|Aniline KLK1;ALB;CYP2E1 DB07105|2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 28879:[DB06728 DB08874] DB06728|Aniline KLK1;ALB;CYP2E1 DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 28880:[DB06728 DB13036] DB06728|Aniline KLK1;ALB;CYP2E1 DB13036|Ramatroban PTGDR2 common genes common pathways 28881:[DB06728 DB14530] DB06728|Aniline KLK1;ALB;CYP2E1 DB14530|Chromous sulfate CYB5A;TF common genes common pathways GO:0001895| retina homeostasis TF;ALB GO:0044267| cellular protein metabolic process TF;ALB GO:0002576| platelet degranulation TF;ALB GO:0043687| post-translational protein modification TF;ALB GO:0055114| oxidation-reduction process CYP2E1;CYB5A 28882:[DB06728 DB01144] DB06728|Aniline KLK1;ALB;CYP2E1 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways GO:0045471| response to ethanol CA3;CYP2E1 28883:[DB06728 DB12781] DB06728|Aniline KLK1;ALB;CYP2E1 DB12781|Balaglitazone CYP3A4;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 28884:[DB06728 DB00558] DB06728|Aniline KLK1;ALB;CYP2E1 DB00558|Zanamivir NEU2 common genes common pathways 28885:[DB06728 DB01623] DB06728|Aniline KLK1;ALB;CYP2E1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP1A2;CYP2D6 GO:0042493| response to drug DRD2;DRD1;CYP2E1;HTR2A;CYP1A2 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP1A2;CYP2E1 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0045471| response to ethanol DRD2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP1A2 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 28886:[DB06728 DB00033] DB06728|Aniline KLK1;ALB;CYP2E1 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 28887:[DB06728 DB00857] DB06728|Aniline KLK1;ALB;CYP2E1 DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2;PTGS1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8;CYP2C19;CYP2C9 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process SQLE;PTGS1;CYP11A1;CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C8;CYP19A1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP11A1;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2D6 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19;CYP2C8 28888:[DB06728 DB04829] DB06728|Aniline KLK1;ALB;CYP2E1 DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug HTR2B;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 28889:[DB06728 DB08168] DB06728|Aniline KLK1;ALB;CYP2E1 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PPIF 28890:[DB06728 DB13997] DB06728|Aniline KLK1;ALB;CYP2E1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways GO:0017144| drug metabolic process UGT1A3;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 28891:[DB06728 DB08624] DB06728|Aniline KLK1;ALB;CYP2E1 DB08624|BENZOTHIAZOLE F2;AHR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;AHR GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process ALB;F2 28892:[DB06728 DB03958] DB06728|Aniline KLK1;ALB;CYP2E1 DB03958|7-methyl-guanosine-5'-triphosphate-5'-guanosine DCPS common genes common pathways GO:0043069| negative regulation of programmed cell death DCPS;ALB 28893:[DB06728 DB01083] DB06728|Aniline KLK1;ALB;CYP2E1 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1;LIPF GO:0055114| oxidation-reduction process FASN;LIPF;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 28894:[DB06728 DB08044] DB06728|Aniline KLK1;ALB;CYP2E1 DB08044|ABT-341 DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28895:[DB06728 DB14582] DB06728|Aniline KLK1;ALB;CYP2E1 DB14582|Patisiran ALB;ORM1;ORM2 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB;ORM2;ORM1 GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 28896:[DB06728 DB00691] DB06728|Aniline KLK1;ALB;CYP2E1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis ACE;KLK1;ACE2 28897:[DB06728 DB02322] DB06728|Aniline KLK1;ALB;CYP2E1 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways 28898:[DB06728 DB05442] DB06728|Aniline KLK1;ALB;CYP2E1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways 28899:[DB06728 DB03864] DB06728|Aniline KLK1;ALB;CYP2E1 DB03864|Monothioglycerol PREP common genes common pathways GO:0006508| proteolysis KLK1;PREP 28900:[DB06728 DB09060] DB06728|Aniline KLK1;ALB;CYP2E1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0042493| response to drug CYP2E1;ABCC2 28901:[DB06728 DB04733] DB06728|Aniline KLK1;ALB;CYP2E1 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways GO:0002576| platelet degranulation ALDOA;ALB 28902:[DB06728 DB00434] DB06728|Aniline KLK1;ALB;CYP2E1 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0017144| drug metabolic process UGT1A3;CYP2E1 GO:0042493| response to drug HTR2A;CYP2E1;HTR2C 28903:[DB06728 DB00949] DB06728|Aniline KLK1;ALB;CYP2E1 DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes CYP2E1 common pathways GO:0045471| response to ethanol GRIN2A;CYP2E1;GRIN2B;GRIN3A GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;GRIN2A GO:0010243| response to organic nitrogen CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 28904:[DB06728 DB08594] DB06728|Aniline KLK1;ALB;CYP2E1 DB08594|TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 28905:[DB06728 DB04114] DB06728|Aniline KLK1;ALB;CYP2E1 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways 28906:[DB06728 DB08912] DB06728|Aniline KLK1;ALB;CYP2E1 DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2C8;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 GO:0043066| negative regulation of apoptotic process RAF1;ALB;BRAF GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6;CYP2C9;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP2B6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2B6 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1B3;SLCO1B1;SLC22A8 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2B6;CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 28907:[DB06728 DB04008] DB06728|Aniline KLK1;ALB;CYP2E1 DB04008|Bis(5-Amidino-Benzimidazolyl)Methane Zinc PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 28908:[DB06728 DB01599] DB06728|Aniline KLK1;ALB;CYP2E1 DB01599|Probucol ABCA1;CES1 common genes common pathways GO:0008202| steroid metabolic process ABCA1;CYP2E1 GO:0042493| response to drug ABCA1;CYP2E1 GO:0006805| xenobiotic metabolic process CES1;CYP2E1 28909:[DB06728 DB12465] DB06728|Aniline KLK1;ALB;CYP2E1 DB12465|Ketanserin HTR2A common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1 28910:[DB06728 DB04559] DB06728|Aniline KLK1;ALB;CYP2E1 DB04559|N-(Chlorophenyl)-N'-Hydroxyguanidine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 28911:[DB06728 DB09258] DB06728|Aniline KLK1;ALB;CYP2E1 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways GO:0044267| cellular protein metabolic process SERPIND1;SERPINC1;ALB GO:0043687| post-translational protein modification SERPIND1;SERPINC1;ALB GO:0006508| proteolysis F10;KLK1 28912:[DB06728 DB02485] DB06728|Aniline KLK1;ALB;CYP2E1 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 28913:[DB06728 DB09046] DB06728|Aniline KLK1;ALB;CYP2E1 DB09046|Metreleptin LEPR common genes common pathways 28914:[DB06728 DB08153] DB06728|Aniline KLK1;ALB;CYP2E1 DB08153|(5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE HSP90AB1 common genes common pathways GO:0042493| response to drug CYP2E1;HSP90AB1 GO:0043066| negative regulation of apoptotic process HSP90AB1;ALB GO:0006805| xenobiotic metabolic process CYP2E1;HSP90AB1 28915:[DB06728 DB03370] DB06728|Aniline KLK1;ALB;CYP2E1 DB03370|FR239087 ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0042493| response to drug CYP2E1;ADA 28916:[DB06728 DB04250] DB06728|Aniline KLK1;ALB;CYP2E1 DB04250|Butyrylthiocholine BCHE;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 28917:[DB06728 DB05936] DB06728|Aniline KLK1;ALB;CYP2E1 DB05936|CVT-6883 ADORA2B common genes common pathways GO:0044267| cellular protein metabolic process ADORA2B;ALB 28918:[DB06728 DB08426] DB06728|Aniline KLK1;ALB;CYP2E1 DB08426|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 28919:[DB06728 DB03305] DB06728|Aniline KLK1;ALB;CYP2E1 DB03305|N5-Iminoethyl-L-Ornithine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 28920:[DB06728 DB01736] DB06728|Aniline KLK1;ALB;CYP2E1 DB01736|[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium SLC25A4 common genes common pathways 28921:[DB06728 DB03604] DB06728|Aniline KLK1;ALB;CYP2E1 DB03604|Tiratricol THRB common genes common pathways 28922:[DB06728 DB00132] DB06728|Aniline KLK1;ALB;CYP2E1 DB00132|Alpha-Linolenic Acid FADS1;FADS2;SLC8A1;TRPV1;ELOVL4;PPARA;NR1H4;PPARD;PPARG;RXRA;FABP7 common genes common pathways GO:0009267| cellular response to starvation FADS1;ALB GO:0015721| bile acid and bile salt transport ALB;RXRA;NR1H4 GO:0043066| negative regulation of apoptotic process ALB;NR1H4;PPARD GO:0010243| response to organic nitrogen TRPV1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;FADS1;FADS2 GO:0042493| response to drug PPARG;CYP2E1;SLC8A1 28923:[DB06728 DB06969] DB06728|Aniline KLK1;ALB;CYP2E1 DB06969|2-amino-4-[2,4-dichloro-5-(2-pyrrolidin-1-ylethoxy)phenyl]-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 28924:[DB06728 DB11755] DB06728|Aniline KLK1;ALB;CYP2E1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0045471| response to ethanol CNR1;CYP2E1 GO:0042493| response to drug CYP2E1;TRPA1 28925:[DB06728 DB03129] DB06728|Aniline KLK1;ALB;CYP2E1 DB03129|[3-(1,3,2-Dioxaborolan-2-Yloxy)Propyl]Guanidine PRSS3 common genes common pathways GO:0006508| proteolysis PRSS3;KLK1 28926:[DB06728 DB00378] DB06728|Aniline KLK1;ALB;CYP2E1 DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 28927:[DB06728 DB01005] DB06728|Aniline KLK1;ALB;CYP2E1 DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;RRM1;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 28928:[DB06728 DB04672] DB06728|Aniline KLK1;ALB;CYP2E1 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways 28929:[DB06728 DB06140] DB06728|Aniline KLK1;ALB;CYP2E1 DB06140|SUVN-502 HTR6 common genes common pathways 28930:[DB06728 DB08918] DB06728|Aniline KLK1;ALB;CYP2E1 DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2J2;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A4;SLC6A2;ABCB1 GO:0055114| oxidation-reduction process CYP2J2;CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CYP2J2 28931:[DB06728 DB08742] DB06728|Aniline KLK1;ALB;CYP2E1 DB08742|1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z) NCOA1;VDR common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA1 28932:[DB06728 DB00702] DB06728|Aniline KLK1;ALB;CYP2E1 DB00702|Icodextrin AMY2A common genes common pathways 28933:[DB06728 DB01425] DB06728|Aniline KLK1;ALB;CYP2E1 DB01425|Alizapride DRD2 common genes common pathways GO:0042493| response to drug CYP2E1;DRD2 GO:0045471| response to ethanol DRD2;CYP2E1 28934:[DB06728 DB01057] DB06728|Aniline KLK1;ALB;CYP2E1 DB01057|Echothiophate BCHE;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;BCHE GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB 28935:[DB06728 DB01998] DB06728|Aniline KLK1;ALB;CYP2E1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways GO:0002576| platelet degranulation ALB;SERPINA1 GO:0043687| post-translational protein modification ALB;SERPINA1 GO:0044267| cellular protein metabolic process ALB;SERPINA1 28936:[DB06728 DB13168] DB06728|Aniline KLK1;ALB;CYP2E1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process FADS1;FADS2;PTGS2;CYP2E1;ALOX5 GO:0042493| response to drug PTGS2;CYP2E1 GO:0098869| PTGS2;ALB GO:0009267| cellular response to starvation ALB;FADS1 28937:[DB06728 DB03066] DB06728|Aniline KLK1;ALB;CYP2E1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 28938:[DB06728 DB11892] DB06728|Aniline KLK1;ALB;CYP2E1 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 28939:[DB06728 DB06756] DB06728|Aniline KLK1;ALB;CYP2E1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BCL2 GO:0055114| oxidation-reduction process CYP2E1;PRODH GO:0042493| response to drug BCL2;CYP2E1;BCHE 28940:[DB06728 DB07389] DB06728|Aniline KLK1;ALB;CYP2E1 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 28941:[DB06728 DB03073] DB06728|Aniline KLK1;ALB;CYP2E1 DB03073|3-Methoxybenzamide PARP1 common genes common pathways 28942:[DB06728 DB03009] DB06728|Aniline KLK1;ALB;CYP2E1 DB03009|2-[(2-Oxo-2-Piperidin-1-Ylethyl)Thio]-6-(Trifluoromethyl)Pyrimidin-4(1h)-One FABP4 common genes common pathways 28943:[DB06728 DB00787] DB06728|Aniline KLK1;ALB;CYP2E1 DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8 GO:0015721| bile acid and bile salt transport ALB;SLC10A2 28944:[DB06728 DB09332] DB06728|Aniline KLK1;ALB;CYP2E1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0017144| drug metabolic process CYP2E1;VKORC1 GO:0044267| cellular protein metabolic process F2;ALB;PROC GO:0043066| negative regulation of apoptotic process PROC;POR;ALB GO:0002576| platelet degranulation PROS1;ALB GO:0042493| response to drug CYP2E1;POR GO:0055114| oxidation-reduction process POR;CYP2E1;VKORC1 GO:0043687| post-translational protein modification ALB;PROC GO:0006805| xenobiotic metabolic process CYP2E1;POR GO:0006508| proteolysis PROC;KLK1;F10;F9;F7;F2 28945:[DB06728 DB01170] DB06728|Aniline KLK1;ALB;CYP2E1 DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug SLC6A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28946:[DB06728 DB01750] DB06728|Aniline KLK1;ALB;CYP2E1 DB01750|1-naphthaleneacetic acid SKP1 common genes common pathways GO:0043687| post-translational protein modification SKP1;ALB 28947:[DB06728 DB02596] DB06728|Aniline KLK1;ALB;CYP2E1 DB02596|Alpha,Beta-Methyleneadenosine-5'-Triphosphate folK;panC;nadE;NMNAT3;carA common genes common pathways 28948:[DB06728 DB07143] DB06728|Aniline KLK1;ALB;CYP2E1 DB07143|D-phenylalanyl-N-benzyl-L-prolinamide F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 28949:[DB06728 DB05327] DB06728|Aniline KLK1;ALB;CYP2E1 DB05327|Ranirestat AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 28950:[DB06728 DB00029] DB06728|Aniline KLK1;ALB;CYP2E1 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0006508| proteolysis PLG;KLK1 GO:0043687| post-translational protein modification ALB;FGA GO:0002576| platelet degranulation PLG;ALB;FGA;SERPINE1 GO:0043066| negative regulation of apoptotic process ALB;PLAUR GO:0044267| cellular protein metabolic process ALB;FGA;PLG 28951:[DB06728 DB08051] DB06728|Aniline KLK1;ALB;CYP2E1 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 28952:[DB06728 DB08127] DB06728|Aniline KLK1;ALB;CYP2E1 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways 28953:[DB06728 DB03023] DB06728|Aniline KLK1;ALB;CYP2E1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1;LCK;LYN GO:0043066| negative regulation of apoptotic process ALB;SRC GO:0002576| platelet degranulation LYN;ALB 28954:[DB06728 DB02359] DB06728|Aniline KLK1;ALB;CYP2E1 DB02359|9-Butyl-8-(2,5-Dimethoxy-Benzyl)-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 28955:[DB06728 DB11779] DB06728|Aniline KLK1;ALB;CYP2E1 DB11779|Danoprevir CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28956:[DB06728 DB04930] DB06728|Aniline KLK1;ALB;CYP2E1 DB04930|Permethrin SCN1A;ESR1;NR1I2;CYP2B6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2B6 GO:0008202| steroid metabolic process NR1I2;CYP2B6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2B6;NR1I2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 28957:[DB06728 DB00550] DB06728|Aniline KLK1;ALB;CYP2E1 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP2E1;CYP1A1 GO:0098869| ALB;TPO GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;TPO;MPO;DBH;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 28958:[DB06728 DB06419] DB06728|Aniline KLK1;ALB;CYP2E1 DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP2E1 28959:[DB06728 DB07274] DB06728|Aniline KLK1;ALB;CYP2E1 DB07274|N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 28960:[DB06728 DB11960] DB06728|Aniline KLK1;ALB;CYP2E1 DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 28961:[DB06728 DB07979] DB06728|Aniline KLK1;ALB;CYP2E1 DB07979|(2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;CYP2E1 28962:[DB06728 DB07827] DB06728|Aniline KLK1;ALB;CYP2E1 DB07827|4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID MMP13 common genes common pathways GO:0006508| proteolysis KLK1;MMP13 GO:0044267| cellular protein metabolic process MMP13;ALB 28963:[DB06728 DB03344] DB06728|Aniline KLK1;ALB;CYP2E1 DB03344|Inositol-(1,3,4,5,6)-Pentakisphosphate CYTH3 common genes common pathways 28964:[DB06728 DB05130] DB06728|Aniline KLK1;ALB;CYP2E1 DB05130|INCB3284 CCR2 common genes common pathways 28965:[DB06728 DB07060] DB06728|Aniline KLK1;ALB;CYP2E1 DB07060|3-(INDOL-3-YL) LACTATE HAO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HAO1 28966:[DB06728 DB09052] DB06728|Aniline KLK1;ALB;CYP2E1 DB09052|Blinatumomab CD19;CD3D common genes common pathways 28967:[DB06728 DB08834] DB06728|Aniline KLK1;ALB;CYP2E1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 28968:[DB06728 DB01129] DB06728|Aniline KLK1;ALB;CYP2E1 DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C8;CYP2C19;CYP2C9;CYP1A1 GO:0042493| response to drug ABCG2;CYP1A1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP1A1;CYP2D6;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C9;CYP1A1;CYP2D6;CYP2C8;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4;CYP2E1 28969:[DB06728 DB07843] DB06728|Aniline KLK1;ALB;CYP2E1 DB07843|5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 28970:[DB06728 DB06589] DB06728|Aniline KLK1;ALB;CYP2E1 DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2;ABCG2;ABCB1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;KDR;FLT4;PDGFRB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0017144| drug metabolic process CYP2D6;CYP2C8;UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0043069| negative regulation of programmed cell death KIT;ALB 28971:[DB06728 DB04697] DB06728|Aniline KLK1;ALB;CYP2E1 DB04697|TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 28972:[DB06728 DB03153] DB06728|Aniline KLK1;ALB;CYP2E1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 28973:[DB06728 DB12651] DB06728|Aniline KLK1;ALB;CYP2E1 DB12651|Bardoxolone CASP8 common genes common pathways GO:0045471| response to ethanol CYP2E1;CASP8 GO:0006508| proteolysis KLK1;CASP8 28974:[DB06728 DB00298] DB06728|Aniline KLK1;ALB;CYP2E1 DB00298|Dapiprazole ADRA1A;ADRA1D;ADRA1B common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 28975:[DB06728 DB12489] DB06728|Aniline KLK1;ALB;CYP2E1 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 28976:[DB06728 DB00698] DB06728|Aniline KLK1;ALB;CYP2E1 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process POR;ALB GO:0042493| response to drug CYP2E1;POR;ABCG2 GO:0055114| oxidation-reduction process POR;CYP2E1 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0006805| xenobiotic metabolic process POR;CYP2E1 28977:[DB06728 DB01261] DB06728|Aniline KLK1;ALB;CYP2E1 DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0006508| proteolysis DPP4;KLK1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 28978:[DB06728 DB00145] DB06728|Aniline KLK1;ALB;CYP2E1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN2A GO:0006805| xenobiotic metabolic process GLYAT;CYP2E1 GO:0042493| response to drug GRIN2A;CYP2E1 GO:0055114| oxidation-reduction process PIPOX;GLDC;CYP2E1 28979:[DB06728 DB08892] DB06728|Aniline KLK1;ALB;CYP2E1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways 28980:[DB06728 DB04410] DB06728|Aniline KLK1;ALB;CYP2E1 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways GO:0006508| proteolysis PRSS2;PRSS1;KLK1 28981:[DB06728 DB00830] DB06728|Aniline KLK1;ALB;CYP2E1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A2;SLC6A3;CYP2E1 GO:0045471| response to ethanol SLC6A3;CYP2E1 28982:[DB06728 DB11805] DB06728|Aniline KLK1;ALB;CYP2E1 DB11805|Saracatinib CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 28983:[DB06728 DB01708] DB06728|Aniline KLK1;ALB;CYP2E1 DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0008202| steroid metabolic process SULT2A1;CYP2E1;CYP3A4;SULT2B1;CYP3A7;NR1I2 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug GRIN2A;GABRG3;CYP2E1 GO:0055114| oxidation-reduction process HSD17B1;CYP2E1;CYP3A4;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol GRIN2A;CYP2E1;GRIN2B;GRIN1;GRIN3A GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;NR1I2 28984:[DB06728 DB14017] DB06728|Aniline KLK1;ALB;CYP2E1 DB14017|H3B-8800 SF3B1 common genes common pathways 28985:[DB06728 DB01108] DB06728|Aniline KLK1;ALB;CYP2E1 DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process HSD3B1;HSD3B2;CYP3A4;CYP2E1 28986:[DB06728 DB06346] DB06728|Aniline KLK1;ALB;CYP2E1 DB06346|Fiboflapon ALOX5AP common genes common pathways 28987:[DB06728 DB04861] DB06728|Aniline KLK1;ALB;CYP2E1 DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 28988:[DB06728 DB00888] DB06728|Aniline KLK1;ALB;CYP2E1 DB00888|Mechlorethamine BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 28989:[DB06728 DB03918] DB06728|Aniline KLK1;ALB;CYP2E1 DB03918|6S-5,6,7,8-Tetrahydrobiopterin NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS3 28990:[DB06728 DB00052] DB06728|Aniline KLK1;ALB;CYP2E1 DB00052|Somatotropin GHR;PRLR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PRLR 28991:[DB06728 DB05967] DB06728|Aniline KLK1;ALB;CYP2E1 DB05967|ANZ-100 KISS1R common genes common pathways 28992:[DB06728 DB12243] DB06728|Aniline KLK1;ALB;CYP2E1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A8 28993:[DB06728 DB05448] DB06728|Aniline KLK1;ALB;CYP2E1 DB05448|PX-12 TXNRD1 common genes common pathways GO:0098869| ALB;TXNRD1 GO:0055114| oxidation-reduction process TXNRD1;CYP2E1 28994:[DB06728 DB09198] DB06728|Aniline KLK1;ALB;CYP2E1 DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0042493| response to drug ABCB1;PPARG;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2E1;CYP1A2 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0043252| sodium-independent organic anion transport ALB;SLCO3A1;SLCO1B1 GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 28995:[DB06728 DB11421] DB06728|Aniline KLK1;ALB;CYP2E1 DB11421|Imidacloprid CHRFAM7A common genes common pathways 28996:[DB06728 DB07151] DB06728|Aniline KLK1;ALB;CYP2E1 DB07151|4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 28997:[DB06728 DB04282] DB06728|Aniline KLK1;ALB;CYP2E1 DB04282|2-deoxy-2-fluoro-α-D-glucose LCT common genes common pathways 28998:[DB06728 DB11830] DB06728|Aniline KLK1;ALB;CYP2E1 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways GO:0042493| response to drug HDAC1;CYP2E1;HDAC2 GO:0043066| negative regulation of apoptotic process HDAC2;HDAC3;ALB;HDAC1 28999:[DB06728 DB02080] DB06728|Aniline KLK1;ALB;CYP2E1 DB02080|1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene PLA2G2A;lepB;TTPA common genes common pathways 29000:[DB06728 DB03298] DB06728|Aniline KLK1;ALB;CYP2E1 DB03298|Phenylphosphate SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug SRC;CYP2E1 29001:[DB06728 DB05532] DB06728|Aniline KLK1;ALB;CYP2E1 DB05532|BMS-488043 FFAR4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;FFAR4 29002:[DB06728 DB05449] DB06728|Aniline KLK1;ALB;CYP2E1 DB05449|FM-VP4 ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 29003:[DB06728 DB07180] DB06728|Aniline KLK1;ALB;CYP2E1 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways 29004:[DB06728 DB09348] DB06728|Aniline KLK1;ALB;CYP2E1 DB09348|Propiolactone ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 29005:[DB06728 DB14001] DB06728|Aniline KLK1;ALB;CYP2E1 DB14001|alpha-Tocopherol succinate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0008202| steroid metabolic process CYP2E1;NR1I2 GO:0098869| GSTP1;ALB;GSTO1 GO:0042493| response to drug SOD1;CYP2E1 GO:0055114| oxidation-reduction process SOD1;CYP2E1;GSTO1;HMOX1;ALOX5;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;ALB;GSTP1;SOD1;GCLC GO:0002576| platelet degranulation ALB;SOD1 GO:0001895| retina homeostasis ALB;SOD1 GO:0045471| response to ethanol SOD1;CYP2E1;NQO1;GSTP1 GO:0006805| xenobiotic metabolic process GSTP1;NQO1;NR1I2;CYP2E1 29006:[DB06728 DB04988] DB06728|Aniline KLK1;ALB;CYP2E1 DB04988|IGN311 EGFR;ERBB2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 29007:[DB06728 DB08058] DB06728|Aniline KLK1;ALB;CYP2E1 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 29008:[DB06728 DB01760] DB06728|Aniline KLK1;ALB;CYP2E1 DB01760|2-Methoxy-3-Isopropylpyrazine LCN9 common genes common pathways 29009:[DB06728 DB07739] DB06728|Aniline KLK1;ALB;CYP2E1 DB07739|(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE PNMT common genes common pathways 29010:[DB06728 DB09539] DB06728|Aniline KLK1;ALB;CYP2E1 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways GO:0008202| steroid metabolic process SOAT1;CYP2E1 29011:[DB06728 DB03953] DB06728|Aniline KLK1;ALB;CYP2E1 DB03953|L-Thiocitrulline NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 29012:[DB06728 DB06733] DB06728|Aniline KLK1;ALB;CYP2E1 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 29013:[DB06728 DB02933] DB06728|Aniline KLK1;ALB;CYP2E1 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 29014:[DB06728 DB02056] DB06728|Aniline KLK1;ALB;CYP2E1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1C3 GO:0008202| steroid metabolic process CYP2E1;AKR1C3 GO:0043252| sodium-independent organic anion transport SLCO2A1;ALB GO:0009267| cellular response to starvation ALB;AKR1C3 29015:[DB06728 DB01294] DB06728|Aniline KLK1;ALB;CYP2E1 DB01294|Bismuth Subsalicylate ALB;TF common genes ALB common pathways GO:0043687| post-translational protein modification TF;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;TF GO:0044267| cellular protein metabolic process TF;ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis TF;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 29016:[DB06728 DB04665] DB06728|Aniline KLK1;ALB;CYP2E1 DB04665|Coumarin CYP2A6;CYP2C9 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2A6;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1;CYP2A6 GO:0008202| steroid metabolic process CYP2E1;CYP2A6;CYP2C9 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 29017:[DB06728 DB06643] DB06728|Aniline KLK1;ALB;CYP2E1 DB06643|Denosumab TNFSF11 common genes common pathways 29018:[DB06728 DB04723] DB06728|Aniline KLK1;ALB;CYP2E1 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways GO:0006508| proteolysis CPB1;KLK1 29019:[DB06728 DB00105] DB06728|Aniline KLK1;ALB;CYP2E1 DB00105|Interferon Alfa-2b, Recombinant IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 29020:[DB06728 DB04821] DB06728|Aniline KLK1;ALB;CYP2E1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0045471| response to ethanol SLC6A3;MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOB;MAOA;CYP2E1;MPO GO:0042493| response to drug SLC6A4;CYP2E1;SLC6A3;SLC6A2;MAOB GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0002576| platelet degranulation ALB;ORM1 29021:[DB06728 DB04653] DB06728|Aniline KLK1;ALB;CYP2E1 DB04653|CBZ-LEU-LEU-TYR-CH2F CAPN1 common genes common pathways GO:0006508| proteolysis KLK1;CAPN1 29022:[DB06728 DB02565] DB06728|Aniline KLK1;ALB;CYP2E1 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways 29023:[DB06728 DB07048] DB06728|Aniline KLK1;ALB;CYP2E1 DB07048|N-[(2R)-5-(aminosulfonyl)-2,3-dihydro-1H-inden-2-yl]-2-propylpentanamide CA2 common genes common pathways 29024:[DB06728 DB00193] DB06728|Aniline KLK1;ALB;CYP2E1 DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2B6;CYP2D6 GO:0045471| response to ethanol OPRK1;GRIN3A;UGT1A1;CYP2E1;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2B6 GO:0042493| response to drug UGT1A1;SLC6A2;HTR2C;CYP2E1;SLC6A4 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2B6;UGT1A1;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2B6;UGT1A1;CYP2E1;CYP3A4 29025:[DB06728 DB01022] DB06728|Aniline KLK1;ALB;CYP2E1 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 29026:[DB06728 DB03166] DB06728|Aniline KLK1;ALB;CYP2E1 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1 29027:[DB06728 DB01075] DB06728|Aniline KLK1;ALB;CYP2E1 DB01075|Diphenhydramine HRH1;CHRM2;CYP2D6;CYP2C9;CYP2C19;CYP2C18;PTGS1;SLC22A2;SLC22A5 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP2C18;PTGS1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C18;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP2C18;PTGS1;CYP2E1;CYP2C19;CYP2D6;CYP2C9 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1 29028:[DB06728 DB07616] DB06728|Aniline KLK1;ALB;CYP2E1 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways 29029:[DB06728 DB07136] DB06728|Aniline KLK1;ALB;CYP2E1 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways GO:0006508| proteolysis KLK1;CPB1 29030:[DB06728 DB04576] DB06728|Aniline KLK1;ALB;CYP2E1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 29031:[DB06728 DB02337] DB06728|Aniline KLK1;ALB;CYP2E1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 29032:[DB06728 DB14641] DB06728|Aniline KLK1;ALB;CYP2E1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0042493| response to drug CYP2E1;ABCB1 29033:[DB06728 DB00116] DB06728|Aniline KLK1;ALB;CYP2E1 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process ALDH1L1;MTHFD2;MTHFD1;CYP2E1;MTHFR GO:0042493| response to drug ABCC2;MTHFR;CYP2E1 29034:[DB06728 DB02063] DB06728|Aniline KLK1;ALB;CYP2E1 DB02063|CRA_16847 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29035:[DB06728 DB02158] DB06728|Aniline KLK1;ALB;CYP2E1 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 29036:[DB06728 DB00767] DB06728|Aniline KLK1;ALB;CYP2E1 DB00767|Benzquinamide HRH1;CHRM4;CHRM1;CHRM5;CHRM2;CHRM3 common genes common pathways 29037:[DB06728 DB05033] DB06728|Aniline KLK1;ALB;CYP2E1 DB05033|INCB7839 ADAM9 common genes common pathways GO:0006508| proteolysis KLK1;ADAM9 29038:[DB06728 DB13998] DB06728|Aniline KLK1;ALB;CYP2E1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0006898| receptor-mediated endocytosis ASGR2;ALB;CALR;LRP1 GO:0006508| proteolysis F2;F9;F10;PROC;KLK1 GO:0044267| cellular protein metabolic process F2;ALB;PROC GO:0043066| negative regulation of apoptotic process PROC;HSPA5;ALB GO:0002576| platelet degranulation VWF;ALB GO:0042493| response to drug CYP2E1;CALR GO:0055114| oxidation-reduction process PHYH;CYP2E1 GO:0043687| post-translational protein modification PROC;ALB 29039:[DB06728 DB08835] DB06728|Aniline KLK1;ALB;CYP2E1 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways GO:0006508| proteolysis KLK1;FOLH1 29040:[DB06728 DB05460] DB06728|Aniline KLK1;ALB;CYP2E1 DB05460|Ezatiostat GSTP1 common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0098869| GSTP1;ALB GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 29041:[DB06728 DB03288] DB06728|Aniline KLK1;ALB;CYP2E1 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways 29042:[DB06728 DB05299] DB06728|Aniline KLK1;ALB;CYP2E1 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0045471| response to ethanol IL2;CYP2E1 29043:[DB06728 DB04877] DB06728|Aniline KLK1;ALB;CYP2E1 DB04877|Voacamine ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 29044:[DB06728 DB00611] DB06728|Aniline KLK1;ALB;CYP2E1 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 29045:[DB06728 DB03114] DB06728|Aniline KLK1;ALB;CYP2E1 DB03114|PAS219 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug CYP2E1;SRC 29046:[DB06728 DB02105] DB06728|Aniline KLK1;ALB;CYP2E1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0042493| response to drug COMT;CYP2E1 29047:[DB06728 DB04960] DB06728|Aniline KLK1;ALB;CYP2E1 DB04960|Tipifarnib FNTB common genes common pathways 29048:[DB06728 DB09072] DB06728|Aniline KLK1;ALB;CYP2E1 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways GO:0055114| oxidation-reduction process ALDH5A1;CYP2E1;ADHFE1 29049:[DB06728 DB03203] DB06728|Aniline KLK1;ALB;CYP2E1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 29050:[DB06728 DB00746] DB06728|Aniline KLK1;ALB;CYP2E1 DB00746|Deferoxamine APP;XDH common genes common pathways GO:0044267| cellular protein metabolic process ALB;APP GO:0002576| platelet degranulation APP;ALB GO:0055114| oxidation-reduction process XDH;CYP2E1 GO:0043687| post-translational protein modification APP;ALB 29051:[DB06728 DB13988] DB06728|Aniline KLK1;ALB;CYP2E1 DB13988|SB-269970 HTR7 common genes common pathways 29052:[DB06728 DB01049] DB06728|Aniline KLK1;ALB;CYP2E1 DB01049|Ergoloid mesylate DRD1;DRD5;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;CYP3A4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0042493| response to drug DRD1;HTR2A;CYP2E1;HTR1B;DRD2;ADRA1A;HTR2C;HTR2B;DRD3 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol HTR3A;DRD2;HTR1B;DRD3;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 29053:[DB06728 DB04350] DB06728|Aniline KLK1;ALB;CYP2E1 DB04350|Argadin CHIT1 common genes common pathways 29054:[DB06728 DB07358] DB06728|Aniline KLK1;ALB;CYP2E1 DB07358|2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 29055:[DB06728 DB00726] DB06728|Aniline KLK1;ALB;CYP2E1 DB00726|Trimipramine SLC6A4;SLC6A2;SLC6A3;HTR2A;HTR1A;ADRA1A;ADRA1B;DRD2;ADRA2B;HRH1;HTR2C;HTR3A;HTR1D;ADRA2A;DRD1;DRD5;ADRB1;ADRB2;ADRB3;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0045471| response to ethanol HTR3A;DRD2;SLC6A3;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0042493| response to drug HTR2C;SLC6A3;ABCB1;ADRA1A;DRD2;SLC6A2;SLC6A4;DRD1;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 29056:[DB06728 DB11726] DB06728|Aniline KLK1;ALB;CYP2E1 DB11726|Encenicline CHRNA7 common genes common pathways 29057:[DB06728 DB00011] DB06728|Aniline KLK1;ALB;CYP2E1 DB00011|Interferon alfa-n1 IFNAR2;IFNAR1 common genes common pathways 29058:[DB06728 DB02908] DB06728|Aniline KLK1;ALB;CYP2E1 DB02908|RU78783 SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;SRC 29059:[DB06728 DB07455] DB06728|Aniline KLK1;ALB;CYP2E1 DB07455|N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide GRIA2 common genes common pathways 29060:[DB06728 DB01055] DB06728|Aniline KLK1;ALB;CYP2E1 DB01055|Mimosine SHMT1;CCL2;TYR common genes common pathways GO:0055114| oxidation-reduction process TYR;CYP2E1 29061:[DB06728 DB00745] DB06728|Aniline KLK1;ALB;CYP2E1 DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C19;CYP3A5;CYP2E1;CYP3A4;CYP1A2 GO:0042493| response to drug SLC6A3;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C9;CYP2B6;CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2B6;CYP2C19 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP3A5;CYP2C19;CYP2C9;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C9;CYP2C19;CYP3A5;CYP1A2;CYP3A4;CYP2E1 GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19 29062:[DB06728 DB07841] DB06728|Aniline KLK1;ALB;CYP2E1 DB07841|Geranylgeranyl diphosphate FNTA;PGGT1B;FNTB;GGPS1;FDPS;RABGGTA;RABGGTB common genes common pathways GO:0043687| post-translational protein modification RABGGTB;RABGGTA;ALB GO:0008202| steroid metabolic process FDPS;CYP2E1 29063:[DB06728 DB04657] DB06728|Aniline KLK1;ALB;CYP2E1 DB04657|Carboxin SDHA common genes common pathways GO:0055114| oxidation-reduction process SDHA;CYP2E1 29064:[DB06728 DB00779] DB06728|Aniline KLK1;ALB;CYP2E1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process TDO2;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB 29065:[DB06728 DB01016] DB06728|Aniline KLK1;ALB;CYP2E1 DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes ALB common pathways GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 GO:0098869| ALB GO:0008202| steroid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4;ABCA1 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLC22A6;SLC22A7;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ABCC3;SLCO2B1;ALB;SLCO1A2;ABCB11 GO:0044267| cellular protein metabolic process ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C19 GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0042493| response to drug ABCG2;ABCC2;ABCB1;ABCC9;ABCC1;CPT1A;KCNJ11;CYP2E1;ABCC8;ABCA1 GO:0006641| triglyceride metabolic process CPT1A;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 29066:[DB06728 DB05928] DB06728|Aniline KLK1;ALB;CYP2E1 DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;ABCC3;SLCO1B1;SLCO1B3 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;SLCO2B1;ALB GO:0008202| steroid metabolic process CYP2C19;CYP1A1;NR1I2;UGT2B7;CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process UGT1A3;CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP1A1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP1A1 GO:0042493| response to drug CYP2E1;CYP1A2;CYP1A1;ABCG2;ABCB1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C19;NR1I2;CYP2E1;CYP3A4;CYP1A2 29067:[DB06728 DB01086] DB06728|Aniline KLK1;ALB;CYP2E1 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 29068:[DB06728 DB00858] DB06728|Aniline KLK1;ALB;CYP2E1 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1 29069:[DB06728 DB01562] DB06728|Aniline KLK1;ALB;CYP2E1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 29070:[DB06728 DB04790] DB06728|Aniline KLK1;ALB;CYP2E1 DB04790|2,5-bis-o-{3-[amino(imino)methyl]phenyl}-1,4:3,6-dianhydro-d-glucitol PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 29071:[DB06728 DB08042] DB06728|Aniline KLK1;ALB;CYP2E1 DB08042|N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB 29072:[DB06728 DB06554] DB06728|Aniline KLK1;ALB;CYP2E1 DB06554|Gaboxadol SLC36A1 common genes common pathways 29073:[DB06728 DB08363] DB06728|Aniline KLK1;ALB;CYP2E1 DB08363|1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine TP53 common genes common pathways GO:0042493| response to drug CYP2E1;TP53 GO:0010243| response to organic nitrogen CYP2E1;TP53 GO:0043066| negative regulation of apoptotic process ALB;TP53 GO:0045471| response to ethanol CYP2E1;TP53 29074:[DB06728 DB02853] DB06728|Aniline KLK1;ALB;CYP2E1 DB02853|D-Proline SLC36A1 common genes common pathways 29075:[DB06728 DB04275] DB06728|Aniline KLK1;ALB;CYP2E1 DB04275|N-acetylserotonin SPR common genes common pathways GO:0055114| oxidation-reduction process SPR;CYP2E1 29076:[DB06728 DB13952] DB06728|Aniline KLK1;ALB;CYP2E1 DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes ALB common pathways GO:0042493| response to drug CYP1A1;BECN1;UGT1A1;ABCG2;ABCB1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP1A2;HSD17B2;CYP1A1;CYP2C9;CYP3A5;CYP2C8;CYP2C19;CYP1B1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process BECN1;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP1A2;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;SLCO1A2;SLCO2B1;ALB;SLCO1C1;NCOA2 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;NR1I2;UGT1A1;CYP3A5;CYP2C8;CYP2C19;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1C1;SLCO4A1;SLC22A11;SLCO1A2;SLCO1B3;SLCO1B1;SLC22A8 GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1;CYP2C9;CYP1A1;CYP2C19;CYP2C8 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP1A1;UGT1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2C8;CYP1B1;CYP2C9;NR1I2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB 29077:[DB06728 DB00016] DB06728|Aniline KLK1;ALB;CYP2E1 DB00016|Erythropoietin EPOR common genes common pathways 29078:[DB06728 DB13875] DB06728|Aniline KLK1;ALB;CYP2E1 DB13875|Harmaline HNMT common genes common pathways 29079:[DB06728 DB06704] DB06728|Aniline KLK1;ALB;CYP2E1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0042493| response to drug CYP2E1;SLC6A2 29080:[DB06728 DB07738] DB06728|Aniline KLK1;ALB;CYP2E1 DB07738|N-[1-(5-bromo-2,3-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide BACE1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;BACE1 GO:0006508| proteolysis KLK1;BACE1 29081:[DB06728 DB06226] DB06728|Aniline KLK1;ALB;CYP2E1 DB06226|Nelipepimut-S HLA-A;HLA-A common genes common pathways 29082:[DB06728 DB03121] DB06728|Aniline KLK1;ALB;CYP2E1 DB03121|(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid PLA2G2A common genes common pathways 29083:[DB06728 DB03251] DB06728|Aniline KLK1;ALB;CYP2E1 DB03251|RWJ-51084 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29084:[DB06728 DB07757] DB06728|Aniline KLK1;ALB;CYP2E1 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways 29085:[DB06728 DB04367] DB06728|Aniline KLK1;ALB;CYP2E1 DB04367|Debromohymenialdisine TNK2;CLK1 common genes common pathways 29086:[DB06728 DB09322] DB06728|Aniline KLK1;ALB;CYP2E1 DB09322|Zinc sulfate ALPPL2 common genes common pathways 29087:[DB06728 DB08553] DB06728|Aniline KLK1;ALB;CYP2E1 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BRAF 29088:[DB06728 DB07544] DB06728|Aniline KLK1;ALB;CYP2E1 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways 29089:[DB06728 DB04178] DB06728|Aniline KLK1;ALB;CYP2E1 DB04178|Di-Stearoyl-3-Sn-Phosphatidylcholine BPI;SLC25A4 common genes common pathways 29090:[DB06728 DB00142] DB06728|Aniline KLK1;ALB;CYP2E1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0045471| response to ethanol GRIN1;GRIN2B;CYP2E1;GRIN2A;GOT2;GRIN3A;ABAT GO:0006508| proteolysis DNPEP;ENPEP;FOLH1;KLK1;CPQ GO:0043066| negative regulation of apoptotic process ALB;GCLC;ASNS GO:0042493| response to drug GAD1;ABAT;PFAS;SLC1A2;GAD2;SLC1A3;GCLM;GRIN2A;CYP2E1 GO:0055114| oxidation-reduction process AASS;ALDH18A1;GLUD1;CYP2E1;GLUD2 GO:0009267| cellular response to starvation ALB;GLUL 29091:[DB06728 DB04147] DB06728|Aniline KLK1;ALB;CYP2E1 DB04147|Lauryl Dimethylamine-N-Oxide MAOB;tesB;ctaC;IGHV3-23;DSTN;RHO;cycA;NFE2L1;PMP2;tonB;CFL1;amtB;DHODH;traF;MAOB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CFL1 GO:0042493| response to drug DHODH;CYP2E1;MAOB GO:0055114| oxidation-reduction process MAOB;CYP2E1;DHODH GO:0006898| receptor-mediated endocytosis ALB;IGHV3-23 GO:0045471| response to ethanol CYP2E1;MAOB GO:0006508| proteolysis IGHV3-23;KLK1 29092:[DB06728 DB07444] DB06728|Aniline KLK1;ALB;CYP2E1 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;DAPK1 29093:[DB06728 DB00872] DB06728|Aniline KLK1;ALB;CYP2E1 DB00872|Conivaptan AVPR1A;AVPR2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 29094:[DB06728 DB00439] DB06728|Aniline KLK1;ALB;CYP2E1 DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2B6;CYP2C9;CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C8;CYP3A7;HMGCR;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0015721| bile acid and bile salt transport ALB;ABCB11;SLCO1B1 GO:0043066| negative regulation of apoptotic process ALB;HMGCR GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C8;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1;ABCB1;ABCG2;ABCC2 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A5;CYP2B6;CYP2C9;HMGCR;CYP3A7;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP3A5 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;HMGCR;UGT1A1 29095:[DB06728 DB11842] DB06728|Aniline KLK1;ALB;CYP2E1 DB11842|Angiotensin II AGTR1 common genes common pathways 29096:[DB06728 DB06964] DB06728|Aniline KLK1;ALB;CYP2E1 DB06964|5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)ISOXAZOLE-3-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 29097:[DB06728 DB00508] DB06728|Aniline KLK1;ALB;CYP2E1 DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0042493| response to drug BCHE;HTR2B;DRD2;ABCB1;CYP2E1;DRD1 GO:0045471| response to ethanol CYP2E1;DRD2 29098:[DB06728 DB06594] DB06728|Aniline KLK1;ALB;CYP2E1 DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9 GO:0042493| response to drug HTR2C;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2;CYP2C9 29099:[DB06728 DB13173] DB06728|Aniline KLK1;ALB;CYP2E1 DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0006898| receptor-mediated endocytosis IGF2R;ALB 29100:[DB06728 DB06680] DB06728|Aniline KLK1;ALB;CYP2E1 DB06680|Asoprisnil PGR common genes common pathways 29101:[DB06728 DB05120] DB06728|Aniline KLK1;ALB;CYP2E1 DB05120|AT1391 INSR common genes common pathways 29102:[DB06728 DB09207] DB06728|Aniline KLK1;ALB;CYP2E1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 GO:0042493| response to drug CYP2E1;DRD2;DRD3 29103:[DB06728 DB04094] DB06728|Aniline KLK1;ALB;CYP2E1 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways 29104:[DB06728 DB04719] DB06728|Aniline KLK1;ALB;CYP2E1 DB04719|DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE CSNK2A1 common genes common pathways 29105:[DB06728 DB00198] DB06728|Aniline KLK1;ALB;CYP2E1 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0002576| platelet degranulation ALB;ABCC4 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0042493| response to drug CYP2E1;ABCC4 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0006805| xenobiotic metabolic process CES1;CYP2E1 29106:[DB06728 DB00188] DB06728|Aniline KLK1;ALB;CYP2E1 DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0006508| proteolysis PSMB1;PSMB5;KLK1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0043687| post-translational protein modification ALB;PSMB5;PSMB1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9;CYP2C19 29107:[DB06728 DB08871] DB06728|Aniline KLK1;ALB;CYP2E1 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0042493| response to drug CYP2E1;BCL2 29108:[DB06728 DB04462] DB06728|Aniline KLK1;ALB;CYP2E1 DB04462|Tetrabromo-2-Benzotriazole CSNK2A1 common genes common pathways 29109:[DB06728 DB05996] DB06728|Aniline KLK1;ALB;CYP2E1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways 29110:[DB06728 DB08015] DB06728|Aniline KLK1;ALB;CYP2E1 DB08015|(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways 29111:[DB06728 DB04197] DB06728|Aniline KLK1;ALB;CYP2E1 DB04197|Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0042493| response to drug CYP2E1;ARG1 29112:[DB06728 DB13894] DB06728|Aniline KLK1;ALB;CYP2E1 DB13894|Agkistrodon piscivorus antivenin PLA2G10 common genes common pathways 29113:[DB06728 DB05915] DB06728|Aniline KLK1;ALB;CYP2E1 DB05915|MYO-029 MSTN common genes common pathways GO:0045471| response to ethanol CYP2E1;MSTN 29114:[DB06728 DB00304] DB06728|Aniline KLK1;ALB;CYP2E1 DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 29115:[DB06728 DB07366] DB06728|Aniline KLK1;ALB;CYP2E1 DB07366|2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 29116:[DB06728 DB09223] DB06728|Aniline KLK1;ALB;CYP2E1 DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug HTR2A;CYP2E1;DRD3;DRD2 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 29117:[DB06728 DB03381] DB06728|Aniline KLK1;ALB;CYP2E1 DB03381|Hexadecanal RHO;DBI common genes common pathways 29118:[DB06728 DB06908] DB06728|Aniline KLK1;ALB;CYP2E1 DB06908|(2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID NCOA1;PPARG common genes common pathways GO:0015721| bile acid and bile salt transport NCOA1;ALB GO:0042493| response to drug CYP2E1;PPARG 29119:[DB06728 DB07981] DB06728|Aniline KLK1;ALB;CYP2E1 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process PTGS1;CYP2E1 29120:[DB06728 DB09285] DB06728|Aniline KLK1;ALB;CYP2E1 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0045471| response to ethanol TBXA2R;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;ALOX5 GO:0042493| response to drug PTGS2;CYP2E1;TBXA2R GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2 29121:[DB06728 DB03048] DB06728|Aniline KLK1;ALB;CYP2E1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DPYD 29122:[DB06728 DB01106] DB06728|Aniline KLK1;ALB;CYP2E1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways 29123:[DB06728 DB01210] DB06728|Aniline KLK1;ALB;CYP2E1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 29124:[DB06728 DB02556] DB06728|Aniline KLK1;ALB;CYP2E1 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:0045471| response to ethanol CRH;CYP2E1 GO:0008202| steroid metabolic process CRH;CYP2E1 GO:0042493| response to drug CRH;CYP2E1 29125:[DB06728 DB06217] DB06728|Aniline KLK1;ALB;CYP2E1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 29126:[DB06728 DB02570] DB06728|Aniline KLK1;ALB;CYP2E1 DB02570|PD150606 CAPNS1 common genes common pathways GO:0006508| proteolysis CAPNS1;KLK1 29127:[DB06728 DB07960] DB06728|Aniline KLK1;ALB;CYP2E1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways 29128:[DB06728 DB02266] DB06728|Aniline KLK1;ALB;CYP2E1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0044267| cellular protein metabolic process ALB;TTR GO:0098869| PTGS2;PTGS1;ALB GO:0008202| steroid metabolic process AKR1C3;CYP2E1 GO:0009267| cellular response to starvation ALB;AKR1C3 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug PPARG;PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;AKR1C3;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 29129:[DB06728 DB02377] DB06728|Aniline KLK1;ALB;CYP2E1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0042493| response to drug PNP;CYP2E1 29130:[DB06728 DB12305] DB06728|Aniline KLK1;ALB;CYP2E1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;SLC6A3;CYP2E1;SLC6A4 GO:0045471| response to ethanol SLC6A3;CYP2E1 29131:[DB06728 DB02463] DB06728|Aniline KLK1;ALB;CYP2E1 DB02463|2-(2-Hydroxy-Phenyl)-1h-Indole-5-Carboxamidine PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29132:[DB06728 DB01209] DB06728|Aniline KLK1;ALB;CYP2E1 DB01209|Dezocine OPRM1;OPRK1 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 29133:[DB06728 DB01619] DB06728|Aniline KLK1;ALB;CYP2E1 DB01619|Phenindamine HRH1 common genes common pathways 29134:[DB06728 DB05892] DB06728|Aniline KLK1;ALB;CYP2E1 DB05892|RI 624 NGF common genes common pathways GO:0043066| negative regulation of apoptotic process NGF;ALB 29135:[DB06728 DB07425] DB06728|Aniline KLK1;ALB;CYP2E1 DB07425|Sobetirome THRB common genes common pathways 29136:[DB06728 DB02942] DB06728|Aniline KLK1;ALB;CYP2E1 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 29137:[DB06728 DB08992] DB06728|Aniline KLK1;ALB;CYP2E1 DB08992|Eperisone CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 29138:[DB06728 DB12752] DB06728|Aniline KLK1;ALB;CYP2E1 DB12752|Bucindolol CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 29139:[DB06728 DB11251] DB06728|Aniline KLK1;ALB;CYP2E1 DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP4F2;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP4F2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;VLDLR;CYP2E1;LDLR;APOBR GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP4F2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0006898| receptor-mediated endocytosis VLDLR;SCARB1;ALB;APOBR;LDLR GO:0006641| triglyceride metabolic process CYP2E1;APOBR GO:0034375| high-density lipoprotein particle remodeling ALB;SCARB1 29140:[DB06728 DB00973] DB06728|Aniline KLK1;ALB;CYP2E1 DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ABCB11;SLCO1B1;ALB;ABCC3 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2E1;CYP3A4;UGT1A3 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process NPC1L1;CYP2C8;UGT1A1;UGT2B15;UGT2B7;SOAT1;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 GO:0042493| response to drug CYP2E1;NPC1L1;ABCG2;ABCC2;ABCB1;ABCG5;ABCG8;UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006508| proteolysis ANPEP;KLK1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;UGT2B15;CYP2C8 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 29141:[DB06728 DB01577] DB06728|Aniline KLK1;ALB;CYP2E1 DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0045471| response to ethanol CYP2E1;MAOB;SLC6A3 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A4;MAOB;SLC6A2;SLC6A3 GO:0055114| oxidation-reduction process MAOA;CYP2E1;MAOB;CYP2D6 29142:[DB06728 DB11723] DB06728|Aniline KLK1;ALB;CYP2E1 DB11723|Dutogliptin DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 29143:[DB06728 DB04153] DB06728|Aniline KLK1;ALB;CYP2E1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH5 29144:[DB06728 DB09330] DB06728|Aniline KLK1;ALB;CYP2E1 DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug ABCB1;ABCG2;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2 29145:[DB06728 DB04792] DB06728|Aniline KLK1;ALB;CYP2E1 DB04792|2,5-O,O-BIS-{4',4''-AMIDINOPHENYL}-1,4:3,6-DIANHYDRO-D-SORBITOL PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29146:[DB06728 DB02161] DB06728|Aniline KLK1;ALB;CYP2E1 DB02161|Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester CES1;CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 29147:[DB06728 DB05004] DB06728|Aniline KLK1;ALB;CYP2E1 DB05004|Peptide YY (3-36) NPY2R;NPY1R;NPY5R;NPY4R common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;NPY5R 29148:[DB06728 DB05740] DB06728|Aniline KLK1;ALB;CYP2E1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0045471| response to ethanol CYP2E1;CHRNB2 29149:[DB06728 DB06670] DB06728|Aniline KLK1;ALB;CYP2E1 DB06670|Odanacatib CTSK;CYP3A4;CYP2C8;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0006508| proteolysis KLK1;CTSK 29150:[DB06728 DB00451] DB06728|Aniline KLK1;ALB;CYP2E1 DB00451|Levothyroxine THRA;THRB;CYP2C8;UGT1A1;TTR;SERPINA7;ALB;SLCO1C1;SLC16A2;ABCB1;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4A1;SLCO4C1;SLC7A5;SLCO2B1 common genes ALB common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP2E1;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug UGT1A1;ABCB1;CYP2E1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2E1 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport SLCO1C1;SLCO4C1;ALB;SLCO2B1;SLCO1A2;SLCO1B3;SLCO1B1;SLC16A2;SLCO4A1 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;SLCO1A2;SLCO1C1;ALB;SLCO2B1 GO:0044267| cellular protein metabolic process TTR;ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 29151:[DB06728 DB03756] DB06728|Aniline KLK1;ALB;CYP2E1 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0042493| response to drug CYP2E1;SREBF1;PPARG GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0015721| bile acid and bile salt transport RXRA;ALB GO:0009267| cellular response to starvation ALB;SREBF1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9;SREBF1 GO:0017144| drug metabolic process CYP2E1;CYP2C9 29152:[DB06728 DB00399] DB06728|Aniline KLK1;ALB;CYP2E1 DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 GO:0042493| response to drug CYP2E1;ABCC1 29153:[DB06728 DB06362] DB06728|Aniline KLK1;ALB;CYP2E1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 29154:[DB06728 DB04768] DB06728|Aniline KLK1;ALB;CYP2E1 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 29155:[DB06728 DB03052] DB06728|Aniline KLK1;ALB;CYP2E1 DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process TBXAS1;CYP2E1 29156:[DB06728 DB02472] DB06728|Aniline KLK1;ALB;CYP2E1 DB02472|6-Hydroxy-7,8-Dihydro Purine Nucleoside ADA common genes common pathways GO:0042493| response to drug CYP2E1;ADA GO:0043066| negative regulation of apoptotic process ADA;ALB 29157:[DB06728 DB00437] DB06728|Aniline KLK1;ALB;CYP2E1 DB00437|Allopurinol XDH;AOX1;XDH;SLC22A8;SLC22A7 common genes common pathways GO:0055114| oxidation-reduction process AOX1;XDH;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A7;ALB GO:0017144| drug metabolic process CYP2E1;AOX1 29158:[DB06728 DB05241] DB06728|Aniline KLK1;ALB;CYP2E1 DB05241|XL765 PIK3CA;PIK3CG;PIK3CD;PIK3CB;MTOR common genes common pathways GO:0009267| cellular response to starvation MTOR;ALB 29159:[DB06728 DB01024] DB06728|Aniline KLK1;ALB;CYP2E1 DB01024|Mycophenolic acid IMPDH1;IMPDH2;UGT1A1;UGT1A9;UGT2B7;UGT1A7;UGT1A6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process UGT1A9;UGT1A6;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;UGT2B7;CYP2E1 GO:0017144| drug metabolic process UGT1A1;UGT1A9;UGT1A6;CYP2E1;UGT1A7 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0055114| oxidation-reduction process CYP2E1;IMPDH2;IMPDH1 29160:[DB06728 DB00473] DB06728|Aniline KLK1;ALB;CYP2E1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 29161:[DB06728 DB00441] DB06728|Aniline KLK1;ALB;CYP2E1 DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0045471| response to ethanol CYP2E1;TYMS GO:0055114| oxidation-reduction process CYP2E1;RRM1 GO:0042493| response to drug TYMS;ABCB1;CYP2E1 29162:[DB06728 DB02467] DB06728|Aniline KLK1;ALB;CYP2E1 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways GO:0043687| post-translational protein modification RAB5A;ALB 29163:[DB06728 DB01664] DB06728|Aniline KLK1;ALB;CYP2E1 DB01664|(S)-Des-Me-Ampa GRIA2 common genes common pathways 29164:[DB06728 DB01046] DB06728|Aniline KLK1;ALB;CYP2E1 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways GO:0017144| drug metabolic process CBR1;CYP2E1 GO:0055114| oxidation-reduction process CBR1;CYP2E1 29165:[DB06728 DB08103] DB06728|Aniline KLK1;ALB;CYP2E1 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 29166:[DB06728 DB03147] DB06728|Aniline KLK1;ALB;CYP2E1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0043066| negative regulation of apoptotic process NQO1;POR;ALB GO:0002576| platelet degranulation CYB5R1;ALB GO:0042493| response to drug CYP2E1;POR;MAOB GO:0055114| oxidation-reduction process CYP2E1;CYB5R3;MAOA;XDH;DLD;AIFM1;ACADS;DPYD;ACAD8;TXNRD1;ACOX1;NOS1;NQO1;ACADM;MAOB;NQO2;IL4I1;IVD;FDXR;DAO;GFER;GSR;NDUFA9;ERO1B;POR;CYB5R1;GCDH GO:0098869| TXNRD1;ALB;GSR GO:0008202| steroid metabolic process FDXR;CYB5R1;CYB5R3;CYP2E1 GO:0006805| xenobiotic metabolic process POR;NQO2;NQO1;CYP2E1;CYB5R3 GO:0045471| response to ethanol CYP2E1;MAOB;NQO1 GO:0006508| proteolysis KLK1;DLD 29167:[DB06728 DB00235] DB06728|Aniline KLK1;ALB;CYP2E1 DB00235|Milrinone PDE3A common genes common pathways GO:0042493| response to drug CYP2E1;PDE3A GO:0043066| negative regulation of apoptotic process PDE3A;ALB 29168:[DB06728 DB03485] DB06728|Aniline KLK1;ALB;CYP2E1 DB03485|Alpha-D-Fucose LTF common genes common pathways GO:0001895| retina homeostasis ALB;LTF GO:0006508| proteolysis KLK1;LTF GO:0044267| cellular protein metabolic process LTF;ALB GO:0043066| negative regulation of apoptotic process LTF;ALB 29169:[DB06728 DB03710] DB06728|Aniline KLK1;ALB;CYP2E1 DB03710|N5-(1-Imino-3-Butenyl)-L-Ornithine NOS1 common genes common pathways GO:0055114| oxidation-reduction process NOS1;CYP2E1 29170:[DB06728 DB14562] DB06728|Aniline KLK1;ALB;CYP2E1 DB14562|Andexanet alfa TFPI common genes common pathways 29171:[DB06728 DB08824] DB06728|Aniline KLK1;ALB;CYP2E1 DB08824|Ioflupane I-123 SLC6A3 common genes common pathways GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0042493| response to drug SLC6A3;CYP2E1 29172:[DB06728 DB05252] DB06728|Aniline KLK1;ALB;CYP2E1 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 29173:[DB06728 DB03701] DB06728|Aniline KLK1;ALB;CYP2E1 DB03701|Vanoxerine SLC6A3;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;SLC6A3 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol SLC6A3;CYP2E1 29174:[DB06728 DB05015] DB06728|Aniline KLK1;ALB;CYP2E1 DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process HDAC2;HDAC3;ALB;HDAC1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2C8 GO:0042493| response to drug HDAC5;HDAC2;CYP2E1;CYP1A2;ABCB1;HDAC1;HDAC4 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP2C8;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 29175:[DB06728 DB07168] DB06728|Aniline KLK1;ALB;CYP2E1 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways 29176:[DB06728 DB07276] DB06728|Aniline KLK1;ALB;CYP2E1 DB07276|5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MAPK8IP1;MAPK8 29177:[DB06728 DB01396] DB06728|Aniline KLK1;ALB;CYP2E1 DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO4C1;SLCO1A2 GO:0008202| steroid metabolic process CYP11A1;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP11A1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ATP1A1;CYP2E1;ABCB1 29178:[DB06728 DB01927] DB06728|Aniline KLK1;ALB;CYP2E1 DB01927|Duroquinone NQO1 common genes common pathways GO:0006805| xenobiotic metabolic process NQO1;CYP2E1 GO:0045471| response to ethanol CYP2E1;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0055114| oxidation-reduction process NQO1;CYP2E1 29179:[DB06728 DB08995] DB06728|Aniline KLK1;ALB;CYP2E1 DB08995|Diosmin AHR common genes common pathways GO:0006805| xenobiotic metabolic process AHR;CYP2E1 29180:[DB06728 DB01390] DB06728|Aniline KLK1;ALB;CYP2E1 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways 29181:[DB06728 DB06717] DB06728|Aniline KLK1;ALB;CYP2E1 DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9 29182:[DB06728 DB01851] DB06728|Aniline KLK1;ALB;CYP2E1 DB01851|Tetrabutylammonium Ion IGKC common genes common pathways GO:0001895| retina homeostasis ALB;IGKC GO:0006898| receptor-mediated endocytosis IGKC;ALB GO:0006508| proteolysis IGKC;KLK1 29183:[DB06728 DB02545] DB06728|Aniline KLK1;ALB;CYP2E1 DB02545|Fexaramine NR1H4 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NR1H4 GO:0043066| negative regulation of apoptotic process NR1H4;ALB 29184:[DB06728 DB03619] DB06728|Aniline KLK1;ALB;CYP2E1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0043066| negative regulation of apoptotic process NR1H4;ALB;GSTP1 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;NR1H4;ALB;SLC10A1;SLC10A2 GO:0098869| GSTP1;ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB 29185:[DB06728 DB06374] DB06728|Aniline KLK1;ALB;CYP2E1 DB06374|Elacestrant ESR1 common genes common pathways 29186:[DB06728 DB00404] DB06728|Aniline KLK1;ALB;CYP2E1 DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0042493| response to drug CYP2E1;GABRG3 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2C9 29187:[DB06728 DB06082] DB06728|Aniline KLK1;ALB;CYP2E1 DB06082|PX-478 HIF1A common genes common pathways GO:0043066| negative regulation of apoptotic process HIF1A;ALB GO:0043687| post-translational protein modification HIF1A;ALB 29188:[DB06728 DB01723] DB06728|Aniline KLK1;ALB;CYP2E1 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways 29189:[DB06728 DB02727] DB06728|Aniline KLK1;ALB;CYP2E1 DB02727|N-Butyl-N'-Hydroxyguanidine NOS1 common genes common pathways GO:0055114| oxidation-reduction process NOS1;CYP2E1 29190:[DB06728 DB01407] DB06728|Aniline KLK1;ALB;CYP2E1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0043066| negative regulation of apoptotic process ALB;NGF GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A1 GO:0017144| drug metabolic process CYP2E1;CYP1A1 29191:[DB06728 DB01439] DB06728|Aniline KLK1;ALB;CYP2E1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;CYP2E1 29192:[DB06728 DB11324] DB06728|Aniline KLK1;ALB;CYP2E1 DB11324|Nonivamide TRPV1 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;TRPV1 29193:[DB06728 DB00072] DB06728|Aniline KLK1;ALB;CYP2E1 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0006508| proteolysis C1S;C1QC;KLK1;C1QA;C1QB;C1R GO:0006898| receptor-mediated endocytosis FCGR1A;ALB;FCGR2B 29194:[DB06728 DB07497] DB06728|Aniline KLK1;ALB;CYP2E1 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways 29195:[DB06728 DB05737] DB06728|Aniline KLK1;ALB;CYP2E1 DB05737|Varespladib methyl PLA2G2A;PLA2G10 common genes common pathways 29196:[DB06728 DB03379] DB06728|Aniline KLK1;ALB;CYP2E1 DB03379|2-Carboxyethylphosphonic Acid TPI1 common genes common pathways 29197:[DB06728 DB07707] DB06728|Aniline KLK1;ALB;CYP2E1 DB07707|(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 29198:[DB06728 DB00959] DB06728|Aniline KLK1;ALB;CYP2E1 DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 29199:[DB06728 DB01411] DB06728|Aniline KLK1;ALB;CYP2E1 DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;NFKB1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0042493| response to drug ABCC2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1 29200:[DB06728 DB13146] DB06728|Aniline KLK1;ALB;CYP2E1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0042493| response to drug ABCB1;ABCC4;GRIN2A;CYP2E1 GO:0002576| platelet degranulation ABCC4;ALB GO:0045471| response to ethanol GRIN1;GRIN2B;CYP2E1;GRIN2A;GRIN3A 29201:[DB06728 DB09555] DB06728|Aniline KLK1;ALB;CYP2E1 DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 29202:[DB06728 DB08346] DB06728|Aniline KLK1;ALB;CYP2E1 DB08346|(5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE HSP90AB1 common genes common pathways GO:0006805| xenobiotic metabolic process HSP90AB1;CYP2E1 GO:0042493| response to drug HSP90AB1;CYP2E1 GO:0043066| negative regulation of apoptotic process HSP90AB1;ALB 29203:[DB06728 DB07678] DB06728|Aniline KLK1;ALB;CYP2E1 DB07678|(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 29204:[DB06728 DB02169] DB06728|Aniline KLK1;ALB;CYP2E1 DB02169|9,10-Deepithio-9,10-Didehydroacanthifolicin PPP1CC common genes common pathways 29205:[DB06728 DB05790] DB06728|Aniline KLK1;ALB;CYP2E1 DB05790|SR 140333 TACR1 common genes common pathways GO:0010193| response to ozone TACR1;CYP2E1 GO:0045471| response to ethanol CYP2E1;TACR1 29206:[DB06728 DB01429] DB06728|Aniline KLK1;ALB;CYP2E1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0002576| platelet degranulation ALB;ORM1;CALM1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 29207:[DB06728 DB03892] DB06728|Aniline KLK1;ALB;CYP2E1 DB03892|5-N-Allyl-Arginine NOS1 common genes common pathways GO:0055114| oxidation-reduction process NOS1;CYP2E1 29208:[DB06728 DB08080] DB06728|Aniline KLK1;ALB;CYP2E1 DB08080|LATRUNCULIN B ACTA1;MKL1;SPIRE2 common genes common pathways 29209:[DB06728 DB09338] DB06728|Aniline KLK1;ALB;CYP2E1 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;AQP1 GO:0042493| response to drug CYP2E1;AQP1 29210:[DB06728 DB00379] DB06728|Aniline KLK1;ALB;CYP2E1 DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2B6 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1;CYP1A2 GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2B6 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;AHR;CYP2B6;CYP2D6 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 29211:[DB06728 DB07315] DB06728|Aniline KLK1;ALB;CYP2E1 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways 29212:[DB06728 DB09418] DB06728|Aniline KLK1;ALB;CYP2E1 DB09418|Potassium perchlorate SLC5A5;ALB common genes ALB common pathways GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 29213:[DB06728 DB06918] DB06728|Aniline KLK1;ALB;CYP2E1 DB06918|2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 29214:[DB06728 DB00526] DB06728|Aniline KLK1;ALB;CYP2E1 DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes CYP2E1 common pathways GO:0042493| response to drug CYP2E1;SOD1;CYP1A1;ABCG2;ABCC2 GO:0055114| oxidation-reduction process CYP1B1;CYP1A1;NQO1;MPO;CYP2E1;SOD1 GO:0010243| response to organic nitrogen CYP2E1 GO:0002576| platelet degranulation ALB;SOD1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP1A1;CYP2E1 GO:0043066| negative regulation of apoptotic process NQO1;ALB;GSTP1;SOD1;MPO GO:0018910| benzene metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1B1;CYP1A1 GO:0098869| ALB;GSTT1;GSTP1 GO:0017144| drug metabolic process CYP1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2E1 GO:0045471| response to ethanol SOD1;CYP2E1;NQO1;GSTP1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP1B1;GSTP1;NQO1;CYP2E1 GO:0001895| retina homeostasis ALB;SOD1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 29215:[DB06728 DB04636] DB06728|Aniline KLK1;ALB;CYP2E1 DB04636|Glutamine t-butyl ester QPCT common genes common pathways 29216:[DB06728 DB06866] DB06728|Aniline KLK1;ALB;CYP2E1 DB06866|6-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 29217:[DB06728 DB04676] DB06728|Aniline KLK1;ALB;CYP2E1 DB04676|Dansyllysine IGHA2 common genes common pathways GO:0001895| retina homeostasis IGHA2;ALB GO:0006898| receptor-mediated endocytosis IGHA2;ALB 29218:[DB06728 DB07082] DB06728|Aniline KLK1;ALB;CYP2E1 DB07082|1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL NR1H2 common genes common pathways 29219:[DB06728 DB05254] DB06728|Aniline KLK1;ALB;CYP2E1 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways GO:0002576| platelet degranulation ALB;SERPINE1 GO:0006508| proteolysis PLAU;KLK1 29220:[DB06728 DB03276] DB06728|Aniline KLK1;ALB;CYP2E1 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways 29221:[DB06728 DB01127] DB06728|Aniline KLK1;ALB;CYP2E1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP19A1 GO:0042493| response to drug CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process NR1I2;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;NR1I2 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 29222:[DB06728 DB12952] DB06728|Aniline KLK1;ALB;CYP2E1 DB12952|Methylprednisone CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 29223:[DB06728 DB02552] DB06728|Aniline KLK1;ALB;CYP2E1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 29224:[DB06728 DB08699] DB06728|Aniline KLK1;ALB;CYP2E1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways 29225:[DB06728 DB00380] DB06728|Aniline KLK1;ALB;CYP2E1 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways 29226:[DB06728 DB07916] DB06728|Aniline KLK1;ALB;CYP2E1 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways GO:0006508| proteolysis KLK1;CASP1 29227:[DB06728 DB02218] DB06728|Aniline KLK1;ALB;CYP2E1 DB02218|N-[4-hydroxymethyl-cyclohexan-6-yl-1,2,3-triol]-4,6-dideoxy-4-aminoglucopyranoside AMY2A;AMY2B;AMY2A common genes common pathways 29228:[DB06728 DB03800] DB06728|Aniline KLK1;ALB;CYP2E1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways GO:0042493| response to drug TYMS;CYP2E1 GO:0045471| response to ethanol CYP2E1;TYMS 29229:[DB06728 DB03956] DB06728|Aniline KLK1;ALB;CYP2E1 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways 29230:[DB06728 DB02665] DB06728|Aniline KLK1;ALB;CYP2E1 DB02665|(1R,2S)-2-Phenylcyclopropanaminium PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 29231:[DB06728 DB02673] DB06728|Aniline KLK1;ALB;CYP2E1 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways 29232:[DB06728 DB07356] DB06728|Aniline KLK1;ALB;CYP2E1 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 29233:[DB06728 DB00697] DB06728|Aniline KLK1;ALB;CYP2E1 DB00697|Tizanidine ADRA2A;ADRA2B;ADRA2C;NISCH;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 29234:[DB06728 DB07946] DB06728|Aniline KLK1;ALB;CYP2E1 DB07946|N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 29235:[DB06728 DB05052] DB06728|Aniline KLK1;ALB;CYP2E1 DB05052|MF101 ESR2 common genes common pathways 29236:[DB06728 DB06243] DB06728|Aniline KLK1;ALB;CYP2E1 DB06243|Eflornithine ODC1 common genes common pathways 29237:[DB06728 DB00195] DB06728|Aniline KLK1;ALB;CYP2E1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ADRB2;ALB 29238:[DB06728 DB03032] DB06728|Aniline KLK1;ALB;CYP2E1 DB03032|S-Octylglutathione GSTM4 common genes common pathways 29239:[DB06728 DB03628] DB06728|Aniline KLK1;ALB;CYP2E1 DB03628|ISO24 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug SRC;CYP2E1 29240:[DB06728 DB04789] DB06728|Aniline KLK1;ALB;CYP2E1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0042493| response to drug ABCC2;CYP2E1 29241:[DB06728 DB07893] DB06728|Aniline KLK1;ALB;CYP2E1 DB07893|PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE IGKC common genes common pathways GO:0006508| proteolysis IGKC;KLK1 GO:0001895| retina homeostasis ALB;IGKC GO:0006898| receptor-mediated endocytosis IGKC;ALB 29242:[DB06728 DB02979] DB06728|Aniline KLK1;ALB;CYP2E1 DB02979|N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS3 29243:[DB06728 DB06448] DB06728|Aniline KLK1;ALB;CYP2E1 DB06448|Lonafarnib FNTA;IGFBP3 common genes common pathways GO:0043687| post-translational protein modification ALB;IGFBP3 GO:0044267| cellular protein metabolic process ALB;IGFBP3 29244:[DB06728 DB01452] DB06728|Aniline KLK1;ALB;CYP2E1 DB01452|Diamorphine OPRM1;OPRK1;OPRD1;CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 GO:0045471| response to ethanol OPRK1;OPRM1;CYP2E1 29245:[DB06728 DB01363] DB06728|Aniline KLK1;ALB;CYP2E1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0045471| response to ethanol CYP2E1;MAOB;SLC6A3 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0042493| response to drug CYP2E1;SLC6A4;SLC6A2;MAOB;SLC6A3 GO:0055114| oxidation-reduction process MAOA;CYP2E1;MAOB 29246:[DB06728 DB06933] DB06728|Aniline KLK1;ALB;CYP2E1 DB06933|N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide MAPK10 common genes common pathways 29247:[DB06728 DB04540] DB06728|Aniline KLK1;ALB;CYP2E1 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 GO:0006805| xenobiotic metabolic process RORA;CYP2E1 29248:[DB06728 DB12445] DB06728|Aniline KLK1;ALB;CYP2E1 DB12445|Nitroaspirin PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0055114| oxidation-reduction process CYP2E1;PTGS1 GO:0098869| ALB;PTGS1 29249:[DB06728 DB02381] DB06728|Aniline KLK1;ALB;CYP2E1 DB02381|nor-NOHA ARG1 common genes common pathways GO:0042493| response to drug CYP2E1;ARG1 29250:[DB06728 DB00499] DB06728|Aniline KLK1;ALB;CYP2E1 DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;NR1I2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP1A1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;CYP2C19;CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP1A1;CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP3A5;AHR;NR1I2;CYP1A2;CYP3A4;CYP2E1 29251:[DB06728 DB14540] DB06728|Aniline KLK1;ALB;CYP2E1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2C8;CYP3A5 GO:0043066| negative regulation of apoptotic process ALB;ANXA1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0042493| response to drug ABCB1;HSD11B2;ABCG2;ANXA1;CYP2E1 GO:0055114| oxidation-reduction process CYP11B1;CYP11B2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP3A5;HSD11B2;HSD3B1 GO:0008202| steroid metabolic process CYP3A7;CYP11B1;CYP11B2;CYP3A4;CYP2E1;CYP3A5;CYP2C8 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;ALB GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 29252:[DB06728 DB01369] DB06728|Aniline KLK1;ALB;CYP2E1 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 29253:[DB06728 DB00474] DB06728|Aniline KLK1;ALB;CYP2E1 DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 29254:[DB06728 DB13953] DB06728|Aniline KLK1;ALB;CYP2E1 DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;NCOA2;SLCO1C1;SLCO1B3;SLCO1B1;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2;SLC22A11;SLCO4A1;SLCO1C1;SLCO2B1;ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;UGT1A1;NR1I2;CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1;CYP2C9;UGT1A1;CYP2C19;CYP2C8 GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process HSD17B2;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP1B1;CYP2C19;CYP2C8;CYP3A5;CYP1A1;CYP2C9 GO:0042493| response to drug CYP2E1;CYP1A2;ABCG2;ABCB1;CYP1A1;BECN1;UGT1A1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP1B1;CYP2C8;CYP2C19;CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;BECN1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19;CYP1A1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C8;CYP2C19;CYP2C9;NR1I2;CYP1A2;CYP3A7;CYP2E1;CYP3A4 29255:[DB06728 DB09291] DB06728|Aniline KLK1;ALB;CYP2E1 DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 29256:[DB06728 DB05301] DB06728|Aniline KLK1;ALB;CYP2E1 DB05301|LAX-101 PLD1;CASP1 common genes common pathways GO:0006508| proteolysis CASP1;KLK1 29257:[DB06728 DB00557] DB06728|Aniline KLK1;ALB;CYP2E1 DB00557|Hydroxyzine HRH1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 29258:[DB06728 DB07735] DB06728|Aniline KLK1;ALB;CYP2E1 DB07735|N-[1-(2,6-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis BACE1;KLK1 29259:[DB06728 DB01351] DB06728|Aniline KLK1;ALB;CYP2E1 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2A6;CYP2E1 GO:0017144| drug metabolic process CYP2A6;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2A6 29260:[DB06728 DB07421] DB06728|Aniline KLK1;ALB;CYP2E1 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways 29261:[DB06728 DB03088] DB06728|Aniline KLK1;ALB;CYP2E1 DB03088|Pidolic Acid VEGFA;AMY2A;IGLC1;TFF2;cycA;ADAM28;KRTAP5-2;HCRT;CCL8;AMY2B;ANG;AMY1A;AMY2A common genes common pathways GO:0002576| platelet degranulation ALB;VEGFA GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0006898| receptor-mediated endocytosis IGLC1;ALB GO:0006508| proteolysis IGLC1;ADAM28;KLK1 29262:[DB06728 DB01380] DB06728|Aniline KLK1;ALB;CYP2E1 DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 29263:[DB06728 DB08173] DB06728|Aniline KLK1;ALB;CYP2E1 DB08173|5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 29264:[DB06728 DB00435] DB06728|Aniline KLK1;ALB;CYP2E1 DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process IDO1;CYP2B6;CYP3A4;CYP2E1;ALDH2;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A2;CYP2E1 29265:[DB06728 DB05509] DB06728|Aniline KLK1;ALB;CYP2E1 DB05509|LI-301 OPRM1;HTR1A common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1 29266:[DB06728 DB13872] DB06728|Aniline KLK1;ALB;CYP2E1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways 29267:[DB06728 DB04741] DB06728|Aniline KLK1;ALB;CYP2E1 DB04741|Myxothiazol UQCRC1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;UQCRC1 29268:[DB06728 DB08507] DB06728|Aniline KLK1;ALB;CYP2E1 DB08507|N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 29269:[DB06728 DB14503] DB06728|Aniline KLK1;ALB;CYP2E1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0044267| cellular protein metabolic process SLC34A1;ALB;SLC34A2 GO:0042493| response to drug CYP2E1;SLC34A1 29270:[DB06728 DB05984] DB06728|Aniline KLK1;ALB;CYP2E1 DB05984|RAF-265 KDR;BRAF common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;BRAF;ALB 29271:[DB06728 DB02029] DB06728|Aniline KLK1;ALB;CYP2E1 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP2E1 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;EPHX2 29272:[DB06728 DB05714] DB06728|Aniline KLK1;ALB;CYP2E1 DB05714|Flovagatran F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 29273:[DB06728 DB11601] DB06728|Aniline KLK1;ALB;CYP2E1 DB11601|Tuberculin Purified Protein Derivative TLR2 common genes common pathways 29274:[DB06728 DB03896] DB06728|Aniline KLK1;ALB;CYP2E1 DB03896|Triphosphoric acid PAPOLA common genes common pathways 29275:[DB06728 DB06190] DB06728|Aniline KLK1;ALB;CYP2E1 DB06190|Solabegron ADRB3 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB3;ALB 29276:[DB06728 DB06787] DB06728|Aniline KLK1;ALB;CYP2E1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 29277:[DB06728 DB03860] DB06728|Aniline KLK1;ALB;CYP2E1 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways 29278:[DB06728 DB06652] DB06728|Aniline KLK1;ALB;CYP2E1 DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A5;CYP3A4;CYP2E1 29279:[DB06728 DB06412] DB06728|Aniline KLK1;ALB;CYP2E1 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2D6;CYP3A5 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0098869| ALB GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP3A5;SRD5A1;CYP3A4;CYP2E1;CYP3A7 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation SRD5A1;ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0042493| response to drug CYP2E1;SRD5A1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process SRD5A1;CYP3A43;CYP3A4;CYP2E1;CYP3A7;MAOA;CYP2D6;CYP3A5 29280:[DB06728 DB01228] DB06728|Aniline KLK1;ALB;CYP2E1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 29281:[DB06728 DB01651] DB06728|Aniline KLK1;ALB;CYP2E1 DB01651|Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside APCS common genes common pathways GO:0044267| cellular protein metabolic process ALB;APCS 29282:[DB06728 DB02559] DB06728|Aniline KLK1;ALB;CYP2E1 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP2E1 29283:[DB06728 DB00604] DB06728|Aniline KLK1;ALB;CYP2E1 DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0045471| response to ethanol HTR3A;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP2B6;CYP2C9;CYP3A7;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP2E1;CYP2A6 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2A6;CYP3A7;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6 GO:0042493| response to drug CYP2E1;HTR2A GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP3A7;CYP2E1;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CYP2A6 29284:[DB06728 DB02222] DB06728|Aniline KLK1;ALB;CYP2E1 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways GO:0042493| response to drug PNP;CYP2E1 29285:[DB06728 DB07111] DB06728|Aniline KLK1;ALB;CYP2E1 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 29286:[DB06728 DB00707] DB06728|Aniline KLK1;ALB;CYP2E1 DB00707|Porfimer sodium LDLR;FCGR1A common genes common pathways GO:0006898| receptor-mediated endocytosis LDLR;FCGR1A;ALB GO:0008202| steroid metabolic process CYP2E1;LDLR 29287:[DB06728 DB08901] DB06728|Aniline KLK1;ALB;CYP2E1 DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0045471| response to ethanol FGFR2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5;CYP2D6;CYP2C8 GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0043066| negative regulation of apoptotic process SRC;ALB;KDR;TEK GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0002576| platelet degranulation ALB;LYN GO:0042493| response to drug LYN;ABCB1;LCK;ABCG2;CYP2E1;SRC;RET GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A5;CYP2C8;CYP2D6 GO:0010243| response to organic nitrogen FLT3;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1 29288:[DB06728 DB11581] DB06728|Aniline KLK1;ALB;CYP2E1 DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BCL2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug ABCG2;ABCB1;CYP2E1;BCL2 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 29289:[DB06728 DB03643] DB06728|Aniline KLK1;ALB;CYP2E1 DB03643|CRA_1144 PRSS1;HPN common genes common pathways GO:0006508| proteolysis PRSS1;KLK1;HPN GO:0043066| negative regulation of apoptotic process ALB;HPN 29290:[DB06728 DB06241] DB06728|Aniline KLK1;ALB;CYP2E1 DB06241|Clenoliximab CD4 common genes common pathways 29291:[DB06728 DB03135] DB06728|Aniline KLK1;ALB;CYP2E1 DB03135|[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid TPI1 common genes common pathways 29292:[DB06728 DB01138] DB06728|Aniline KLK1;ALB;CYP2E1 DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP2B6;CYP2C8;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLC22A12 GO:0008202| steroid metabolic process CYP2B6;NR1I2;CYP2C9;CYP2C8;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2C8 GO:0015721| bile acid and bile salt transport ABCC3;ALB;ABCB11 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2B6;CYP2C8 GO:0002576| platelet degranulation ABCC4;ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;ABCC4;CYP2C9;CYP2B6;CYP2C8 GO:0042493| response to drug ABCC6;ABCC1;ABCC2;CYP2E1;SLC22A12;ABCC4 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 29293:[DB06728 DB06713] DB06728|Aniline KLK1;ALB;CYP2E1 DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes ALB common pathways GO:0043687| post-translational protein modification ALB;STS GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;STS GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 29294:[DB06728 DB02126] DB06728|Aniline KLK1;ALB;CYP2E1 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis HBB;HBA1;ALB GO:0098869| HBB;HBA1;ALB 29295:[DB06728 DB00637] DB06728|Aniline KLK1;ALB;CYP2E1 DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2E1;CYP2J2;CYP3A4;CYP3A7 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP2E1;CYP2J2;CYP3A4;CYP3A7 GO:0019373| epoxygenase P450 pathway CYP2J2;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 29296:[DB06728 DB01252] DB06728|Aniline KLK1;ALB;CYP2E1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0042493| response to drug ABCC8;CYP2E1;PPARG GO:0017144| drug metabolic process CYP2E1;UGT1A3 GO:0008202| steroid metabolic process UGT2B7;CYP2E1 29297:[DB06728 DB04786] DB06728|Aniline KLK1;ALB;CYP2E1 DB04786|Suramin P2RY2;SIRT5;FSHR;RYR1;F2;PLA2G2A;ARSA;PLA2G4A common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0043687| post-translational protein modification ARSA;ALB GO:0044267| cellular protein metabolic process ALB;F2 29298:[DB06728 DB00814] DB06728|Aniline KLK1;ALB;CYP2E1 DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;PTGS1;CYP2C9;CYP2C8 GO:0002576| platelet degranulation ALB;ABCC4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process ABCC4;PTGS1;PTGS2;PGD;CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0042493| response to drug ABCC4;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1;ABCC4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP2E1;CYP3A4 GO:0098869| ALB;PTGS1;PTGS2 29299:[DB06728 DB06262] DB06728|Aniline KLK1;ALB;CYP2E1 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0042493| response to drug SLC6A2;ADRA1A;CYP2E1 GO:0055114| oxidation-reduction process PAH;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 29300:[DB06728 DB08214] DB06728|Aniline KLK1;ALB;CYP2E1 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 29301:[DB06728 DB01254] DB06728|Aniline KLK1;ALB;CYP2E1 DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0043069| negative regulation of programmed cell death KIT;ALB GO:0045471| response to ethanol FYN;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP3A5;CYP1B1;FMO3 GO:0009267| cellular response to starvation ALB;HSPA8 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1;CYP3A5;CYP1B1 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process FMO3;CYP1A1;CYP3A5;CYP1B1;CYP3A4;CYP2E1;CYP1A2 GO:0042493| response to drug ABCB1;LCK;ABCG2;CYP1A1;FYN;LYN;SRC;PPAT;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP1A1;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process SRC;NR4A3;STAT5B;PDGFRB;ALB GO:0002576| platelet degranulation ALB;LYN 29302:[DB06728 DB01059] DB06728|Aniline KLK1;ALB;CYP2E1 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP3A4;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP3A5;CYP3A4;CYP2E1;CYP3A7;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP1A1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0008202| steroid metabolic process CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP1A1;CYP3A5 GO:0017144| drug metabolic process CYP1A1;CYP2E1;CYP3A4;CYP1A2 29303:[DB06728 DB02779] DB06728|Aniline KLK1;ALB;CYP2E1 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways GO:0006641| triglyceride metabolic process PTPN11;CYP2E1 29304:[DB06728 DB08555] DB06728|Aniline KLK1;ALB;CYP2E1 DB08555|1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline MAPK10 common genes common pathways 29305:[DB06728 DB08495] DB06728|Aniline KLK1;ALB;CYP2E1 DB08495|4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 29306:[DB06728 DB05303] DB06728|Aniline KLK1;ALB;CYP2E1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways 29307:[DB06728 DB07171] DB06728|Aniline KLK1;ALB;CYP2E1 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways GO:0006508| proteolysis ECE1;KLK1 29308:[DB06728 DB00002] DB06728|Aniline KLK1;ALB;CYP2E1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0006508| proteolysis C1QC;C1S;KLK1;C1QA;C1QB;C1R 29309:[DB06728 DB00338] DB06728|Aniline KLK1;ALB;CYP2E1 DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C19;CYP2C8;CYP2D6;AHR;CYP2C9;CYP2C18;CYP1A2;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ABCC3;ALB GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP1B1;CYP3A4;CYP2E1;CYP11A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP1A1 GO:0042493| response to drug CYP1A1;ABCB1;ABCG2;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP2D6;CYP2C8;CYP2C19;CYP1B1;CYP11A1;CYP3A4;CYP2E1;CYP1A2;CYP2C18 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C8;CYP2C19;CYP1B1;CYP2E1;CYP1A2;CYP2C18 29310:[DB06728 DB03950] DB06728|Aniline KLK1;ALB;CYP2E1 DB03950|(S)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways 29311:[DB06728 DB09146] DB06728|Aniline KLK1;ALB;CYP2E1 DB09146|Iron saccharate HBA1;TF common genes common pathways GO:0002576| platelet degranulation TF;ALB GO:0043687| post-translational protein modification ALB;TF GO:0098869| HBA1;ALB GO:0044267| cellular protein metabolic process TF;ALB GO:0006898| receptor-mediated endocytosis ALB;HBA1 GO:0001895| retina homeostasis TF;ALB 29312:[DB06728 DB09449] DB06728|Aniline KLK1;ALB;CYP2E1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0044267| cellular protein metabolic process SLC34A2;ALB;SLC34A1 GO:0042493| response to drug CYP2E1;SLC34A1 29313:[DB06728 DB01964] DB06728|Aniline KLK1;ALB;CYP2E1 DB01964|AL5424 CA2 common genes common pathways 29314:[DB06728 DB00533] DB06728|Aniline KLK1;ALB;CYP2E1 DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP1A2;CYP2E1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0010243| response to organic nitrogen ABCC4;PTGS2;CYP2E1 GO:0042493| response to drug ABCC4;CYP2E1;PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;PTGS2;CYP1A2;PTGS1;ABCC4;CYP2C9;CYP2C8 GO:0098869| ALB;PTGS2;PTGS1 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C8;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;PTGS1;CYP2C9;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2 29315:[DB06728 DB05428] DB06728|Aniline KLK1;ALB;CYP2E1 DB05428|motexafin gadolinium TXNRD1;TXNRD2;RRM2 common genes common pathways GO:0055114| oxidation-reduction process TXNRD1;TXNRD2;CYP2E1;RRM2 GO:0098869| TXNRD2;TXNRD1;ALB 29316:[DB06728 DB07049] DB06728|Aniline KLK1;ALB;CYP2E1 DB07049|(2R)-1-[(4-tert-butylphenyl)sulfonyl]-2-methyl-4-(4-nitrophenyl)piperazine HSD11B1 common genes common pathways GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 GO:0008202| steroid metabolic process HSD11B1;CYP2E1 29317:[DB06728 DB00083] DB06728|Aniline KLK1;ALB;CYP2E1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 29318:[DB06728 DB08787] DB06728|Aniline KLK1;ALB;CYP2E1 DB08787|4-(2,4-dichlorophenyl)-5-phenyldiazenyl-pyrimidin-2-amine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 29319:[DB06728 DB02201] DB06728|Aniline KLK1;ALB;CYP2E1 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 29320:[DB06728 DB13269] DB06728|Aniline KLK1;ALB;CYP2E1 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0042493| response to drug SCN11A;CYP2E1 29321:[DB06728 DB07146] DB06728|Aniline KLK1;ALB;CYP2E1 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways GO:0042493| response to drug CYP2E1;LCK 29322:[DB06728 DB06772] DB06728|Aniline KLK1;ALB;CYP2E1 DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C8 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A5;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0002576| platelet degranulation ALB;TUBA4A GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 29323:[DB06728 DB07975] DB06728|Aniline KLK1;ALB;CYP2E1 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHODH GO:0042493| response to drug CYP2E1;DHODH 29324:[DB06728 DB04739] DB06728|Aniline KLK1;ALB;CYP2E1 DB04739|4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug SRC;CYP2E1 29325:[DB06728 DB13775] DB06728|Aniline KLK1;ALB;CYP2E1 DB13775|Tertatolol CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 29326:[DB06728 DB08213] DB06728|Aniline KLK1;ALB;CYP2E1 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways GO:0006508| proteolysis CASP3;KLK1 GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0042493| response to drug CYP2E1;CASP3 29327:[DB06728 DB09200] DB06728|Aniline KLK1;ALB;CYP2E1 DB09200|Rivoglitazone CYP3A4;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 29328:[DB06728 DB03555] DB06728|Aniline KLK1;ALB;CYP2E1 DB03555|CRA_11092 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 29329:[DB06728 DB13950] DB06728|Aniline KLK1;ALB;CYP2E1 DB13950|WIN 55212-2 CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 29330:[DB06728 DB02034] DB06728|Aniline KLK1;ALB;CYP2E1 DB02034|Tridolgosir MAN2A1 common genes common pathways 29331:[DB06728 DB01395] DB06728|Aniline KLK1;ALB;CYP2E1 DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| PTGS2;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2;BCHE GO:0043066| negative regulation of apoptotic process PTGS2;ALB 29332:[DB06728 DB01126] DB06728|Aniline KLK1;ALB;CYP2E1 DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0009267| cellular response to starvation SRD5A1;ALB GO:0008202| steroid metabolic process SRD5A1;CYP3A4;CYP2E1;SRD5A2 GO:0042493| response to drug SRD5A1;CYP2E1;SRD5A2 GO:0055114| oxidation-reduction process SRD5A2;CYP2E1;CYP3A4;SRD5A1 29333:[DB06728 DB02986] DB06728|Aniline KLK1;ALB;CYP2E1 DB02986|N-(2-Thienylmethyl)-2,5-Thiophenedisulfonamide CA2 common genes common pathways 29334:[DB06728 DB03693] DB06728|Aniline KLK1;ALB;CYP2E1 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways 29335:[DB06728 DB05041] DB06728|Aniline KLK1;ALB;CYP2E1 DB05041|RP101 UPP1;UPP2 common genes common pathways 29336:[DB06728 DB13866] DB06728|Aniline KLK1;ALB;CYP2E1 DB13866|Etynodiol CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 29337:[DB06728 DB02624] DB06728|Aniline KLK1;ALB;CYP2E1 DB02624|Homoserine Lactone SLC9A1 common genes common pathways GO:0043066| negative regulation of apoptotic process SLC9A1;ALB 29338:[DB06728 DB08595] DB06728|Aniline KLK1;ALB;CYP2E1 DB08595|4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 29339:[DB06728 DB11348] DB06728|Aniline KLK1;ALB;CYP2E1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB;CALB1;SLC34A2;NUCB1;SLC34A1 GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation CADPS2;ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0043687| post-translational protein modification NUCB1;ALB GO:0042493| response to drug CALR;SLC8A1;SLC34A1;CYP2E1 GO:0002576| platelet degranulation CALM1;SPARC;ALB GO:0043066| negative regulation of apoptotic process CIB1;ALB;RGN;TPT1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB;CALR;SPARC GO:0006508| proteolysis KLK1;PEF1;SRI;GCA;PDCD6 GO:0045471| response to ethanol CYP2E1;SPARC GO:0019836| hemolysis by symbiont of host erythrocytes ALB 29340:[DB06728 DB08230] DB06728|Aniline KLK1;ALB;CYP2E1 DB08230|5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;ALB 29341:[DB06728 DB07644] DB06728|Aniline KLK1;ALB;CYP2E1 DB07644|5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine DCPS common genes common pathways GO:0043069| negative regulation of programmed cell death DCPS;ALB 29342:[DB06728 DB09389] DB06728|Aniline KLK1;ALB;CYP2E1 DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0009267| cellular response to starvation ALB;SRD5A1 GO:0008202| steroid metabolic process SRD5A1;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process SRD5A1;CYP2E1;CYP3A4;CYP19A1 GO:0042493| response to drug CYP2E1;SRD5A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 29343:[DB06728 DB12191] DB06728|Aniline KLK1;ALB;CYP2E1 DB12191|Obatoclax BCL2 common genes common pathways GO:0042493| response to drug CYP2E1;BCL2 GO:0043066| negative regulation of apoptotic process BCL2;ALB 29344:[DB06728 DB03039] DB06728|Aniline KLK1;ALB;CYP2E1 DB03039|4-(Aminosulfonyl)-N-[(2,5-Difluorophenyl)Methyl]-Benzamide CA2 common genes common pathways 29345:[DB06728 DB04352] DB06728|Aniline KLK1;ALB;CYP2E1 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 29346:[DB06728 DB03626] DB06728|Aniline KLK1;ALB;CYP2E1 DB03626|5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;NQO1 GO:0055114| oxidation-reduction process CYP2E1;NQO1 GO:0006805| xenobiotic metabolic process NQO1;CYP2E1 GO:0045471| response to ethanol NQO1;CYP2E1 29347:[DB06728 DB03727] DB06728|Aniline KLK1;ALB;CYP2E1 DB03727|Coproporphyrin I UROD common genes common pathways 29348:[DB06728 DB00409] DB06728|Aniline KLK1;ALB;CYP2E1 DB00409|Remoxipride DRD2;DRD4;DRD3;HTR2A;SIGMAR1;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug HTR2A;CYP2E1;DRD3;DRD2 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0045471| response to ethanol CYP2E1;DRD2;DRD3 29349:[DB06728 DB08807] DB06728|Aniline KLK1;ALB;CYP2E1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug HTR1B;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0045471| response to ethanol CYP2E1;HTR1B 29350:[DB06728 DB08406] DB06728|Aniline KLK1;ALB;CYP2E1 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 29351:[DB06728 DB05057] DB06728|Aniline KLK1;ALB;CYP2E1 DB05057|Erdosteine ADA common genes common pathways GO:0042493| response to drug ADA;CYP2E1 GO:0043066| negative regulation of apoptotic process ADA;ALB 29352:[DB06728 DB11130] DB06728|Aniline KLK1;ALB;CYP2E1 DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB;B2M GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 GO:0098869| ALB GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process B2M;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0042493| response to drug B2M;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB 29353:[DB06728 DB06734] DB06728|Aniline KLK1;ALB;CYP2E1 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 29354:[DB06728 DB00578] DB06728|Aniline KLK1;ALB;CYP2E1 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 29355:[DB06728 DB07708] DB06728|Aniline KLK1;ALB;CYP2E1 DB07708|3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 29356:[DB06728 DB03006] DB06728|Aniline KLK1;ALB;CYP2E1 DB03006|Arsanilic acid LYZ common genes common pathways GO:0044267| cellular protein metabolic process LYZ;ALB GO:0001895| retina homeostasis ALB;LYZ 29357:[DB06728 DB05483] DB06728|Aniline KLK1;ALB;CYP2E1 DB05483|PCL-016 UBR4;ZFY common genes common pathways 29358:[DB06728 DB08461] DB06728|Aniline KLK1;ALB;CYP2E1 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways 29359:[DB06728 DB08751] DB06728|Aniline KLK1;ALB;CYP2E1 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways 29360:[DB06728 DB01153] DB06728|Aniline KLK1;ALB;CYP2E1 DB01153|Sertaconazole CYP51A1 common genes common pathways GO:0008202| steroid metabolic process CYP51A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP51A1 29361:[DB06728 DB07172] DB06728|Aniline KLK1;ALB;CYP2E1 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 29362:[DB06728 DB00589] DB06728|Aniline KLK1;ALB;CYP2E1 DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol HTR1B;DRD2;DRD3;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0042493| response to drug DRD3;HTR2C;HTR2B;HTR1B;DRD2;CYP2E1;HTR2A;DRD1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0043066| negative regulation of apoptotic process HTR2B;ALB 29363:[DB06728 DB09502] DB06728|Aniline KLK1;ALB;CYP2E1 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0045471| response to ethanol SLC2A4;CYP2E1 29364:[DB06728 DB01070] DB06728|Aniline KLK1;ALB;CYP2E1 DB01070|Dihydrotachysterol VDR common genes common pathways 29365:[DB06728 DB04683] DB06728|Aniline KLK1;ALB;CYP2E1 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways 29366:[DB06728 DB05505] DB06728|Aniline KLK1;ALB;CYP2E1 DB05505|NM-702 TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;TBXAS1 29367:[DB06728 DB01200] DB06728|Aniline KLK1;ALB;CYP2E1 DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD3;DRD2;HTR1B GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug HTR2B;HTR2C;ADRA1A;DRD2;ABCB1;HTR1B;DRD3;DRD1;HTR2A;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 29368:[DB06728 DB02763] DB06728|Aniline KLK1;ALB;CYP2E1 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways 29369:[DB06728 DB01240] DB06728|Aniline KLK1;ALB;CYP2E1 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PTGIS 29370:[DB06728 DB08847] DB06728|Aniline KLK1;ALB;CYP2E1 DB08847|Hydroxyproline SLC36A1 common genes common pathways 29371:[DB06728 DB02383] DB06728|Aniline KLK1;ALB;CYP2E1 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;AKR1A1;AKR1B10;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0008202| steroid metabolic process AKR1B10;CYP2E1 29372:[DB06728 DB11607] DB06728|Aniline KLK1;ALB;CYP2E1 DB11607|Efmoroctocog alfa VWF common genes common pathways GO:0002576| platelet degranulation VWF;ALB 29373:[DB06728 DB05039] DB06728|Aniline KLK1;ALB;CYP2E1 DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;UGT1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 29374:[DB06728 DB04825] DB06728|Aniline KLK1;ALB;CYP2E1 DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0002576| platelet degranulation CALM1;ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 29375:[DB06728 DB00152] DB06728|Aniline KLK1;ALB;CYP2E1 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0055114| oxidation-reduction process CYP4B1;CYP2E1 29376:[DB06728 DB04964] DB06728|Aniline KLK1;ALB;CYP2E1 DB04964|Oregovomab MUC16 common genes common pathways 29377:[DB06728 DB07225] DB06728|Aniline KLK1;ALB;CYP2E1 DB07225|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE CTSB common genes common pathways GO:0006508| proteolysis KLK1;CTSB 29378:[DB06728 DB05476] DB06728|Aniline KLK1;ALB;CYP2E1 DB05476|WX-UK1 PLAUR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PLAUR 29379:[DB06728 DB04727] DB06728|Aniline KLK1;ALB;CYP2E1 DB04727|N-(4-{4-AMINO-6-[4-(METHYLOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-5-YL}PHENYL)-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB 29380:[DB06728 DB00097] DB06728|Aniline KLK1;ALB;CYP2E1 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways 29381:[DB06728 DB03971] DB06728|Aniline KLK1;ALB;CYP2E1 DB03971|Acarbose Derived Hexasaccharide AMY2A;AMY2A common genes common pathways 29382:[DB06728 DB00836] DB06728|Aniline KLK1;ALB;CYP2E1 DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2B6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP2B6;CYP3A4;CYP2E1 GO:0002576| platelet degranulation CALM1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C8 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2D6;CYP2B6 GO:0042493| response to drug ABCB1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 29383:[DB06728 DB00210] DB06728|Aniline KLK1;ALB;CYP2E1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0045471| response to ethanol RARA;CYP2E1 GO:0098869| PTGS2;ALB GO:0015721| bile acid and bile salt transport RXRA;ALB GO:0043066| negative regulation of apoptotic process ALB;RARB;PTGS2;RARG;RARA GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 29384:[DB06728 DB07848] DB06728|Aniline KLK1;ALB;CYP2E1 DB07848|5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 29385:[DB06728 DB05421] DB06728|Aniline KLK1;ALB;CYP2E1 DB05421|CP-122721 TACR1 common genes common pathways GO:0045471| response to ethanol CYP2E1;TACR1 GO:0010193| response to ozone TACR1;CYP2E1 29386:[DB06728 DB12332] DB06728|Aniline KLK1;ALB;CYP2E1 DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;ALB GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C19;UGT1A1;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLC22A8;SLCO1B1;ALB;SLC22A6 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6;CYP3A5;UGT1A1;CYP2C9 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0042493| response to drug ABCC4;CYP2E1;CYP1A2;ABCG2;ABCB1;UGT1A1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A43;ABCC4;CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2C19;CYP2C8 GO:0002576| platelet degranulation ABCC4;ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;UGT1A1 29387:[DB06728 DB01155] DB06728|Aniline KLK1;ALB;CYP2E1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 29388:[DB06728 DB01800] DB06728|Aniline KLK1;ALB;CYP2E1 DB01800|N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium ARSA common genes common pathways GO:0043687| post-translational protein modification ARSA;ALB 29389:[DB06728 DB06921] DB06728|Aniline KLK1;ALB;CYP2E1 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways GO:0006508| proteolysis KLK1;CPB1 29390:[DB06728 DB05431] DB06728|Aniline KLK1;ALB;CYP2E1 DB05431|MLN-977 ALOX5 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;CYP2E1 29391:[DB06728 DB02998] DB06728|Aniline KLK1;ALB;CYP2E1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 29392:[DB06728 DB14635] DB06728|Aniline KLK1;ALB;CYP2E1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2B6;CYP3A4;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP2B6;CBR1;CYP3A4;CYP2E1;CYP1A2 GO:0098869| GSTP1;GSTA1;ALB GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CBR1;CYP2B6;CYP2C9;CYP2D6 GO:0042493| response to drug CYP1A2;CYP2E1;PPARG;ABCB1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2B6 GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;GSTP1;CYP2C9;CYP2B6;CYP2E1;CYP3A4;CYP1A2 29393:[DB06728 DB00877] DB06728|Aniline KLK1;ALB;CYP2E1 DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0042493| response to drug ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0009267| cellular response to starvation ALB;MTOR GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 29394:[DB06728 DB11712] DB06728|Aniline KLK1;ALB;CYP2E1 DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 29395:[DB06728 DB02813] DB06728|Aniline KLK1;ALB;CYP2E1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways GO:0044267| cellular protein metabolic process ALB;HEXB 29396:[DB06728 DB04318] DB06728|Aniline KLK1;ALB;CYP2E1 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways GO:0006508| proteolysis MMP11;KLK1 29397:[DB06728 DB02177] DB06728|Aniline KLK1;ALB;CYP2E1 DB02177|1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine ITGAL common genes common pathways 29398:[DB06728 DB02347] DB06728|Aniline KLK1;ALB;CYP2E1 DB02347|2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid GRIA2 common genes common pathways 29399:[DB06728 DB02142] DB06728|Aniline KLK1;ALB;CYP2E1 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways 29400:[DB06728 DB06912] DB06728|Aniline KLK1;ALB;CYP2E1 DB06912|UNDECA-3,7-DIENE-1,3,7,11-TETRACARBALDEHYDE LYZ common genes common pathways GO:0001895| retina homeostasis LYZ;ALB GO:0044267| cellular protein metabolic process LYZ;ALB 29401:[DB06728 DB12334] DB06728|Aniline KLK1;ALB;CYP2E1 DB12334|Milataxel TUBB1;TUBB common genes common pathways 29402:[DB06728 DB06157] DB06728|Aniline KLK1;ALB;CYP2E1 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;CYP2E1 29403:[DB06728 DB08082] DB06728|Aniline KLK1;ALB;CYP2E1 DB08082|N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE MAOB common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MAOB GO:0042493| response to drug CYP2E1;MAOB GO:0045471| response to ethanol MAOB;CYP2E1 29404:[DB06728 DB07462] DB06728|Aniline KLK1;ALB;CYP2E1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0042493| response to drug COMT;CYP2E1 29405:[DB06728 DB09303] DB06728|Aniline KLK1;ALB;CYP2E1 DB09303|Evolocumab PCSK9 common genes common pathways GO:0006508| proteolysis KLK1;PCSK9 GO:0006641| triglyceride metabolic process CYP2E1;PCSK9 GO:0043687| post-translational protein modification ALB;PCSK9 GO:0009267| cellular response to starvation ALB;PCSK9 GO:0008202| steroid metabolic process CYP2E1;PCSK9 GO:0044267| cellular protein metabolic process ALB;PCSK9 29406:[DB06728 DB06212] DB06728|Aniline KLK1;ALB;CYP2E1 DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 29407:[DB06728 DB01284] DB06728|Aniline KLK1;ALB;CYP2E1 DB01284|Tetracosactide MC2R common genes common pathways 29408:[DB06728 DB03484] DB06728|Aniline KLK1;ALB;CYP2E1 DB03484|L-Alpha-Glycerophosphorylethanolamine ANXA5 common genes common pathways GO:0002576| platelet degranulation ANXA5;ALB GO:0043066| negative regulation of apoptotic process ALB;ANXA5 29409:[DB06728 DB05913] DB06728|Aniline KLK1;ALB;CYP2E1 DB05913|OSI-930 KIT;FLT1 common genes common pathways GO:0043069| negative regulation of programmed cell death KIT;ALB 29410:[DB06728 DB00438] DB06728|Aniline KLK1;ALB;CYP2E1 DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 29411:[DB06728 DB04010] DB06728|Aniline KLK1;ALB;CYP2E1 DB04010|2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide PARP1 common genes common pathways 29412:[DB06728 DB06124] DB06728|Aniline KLK1;ALB;CYP2E1 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways GO:0043066| negative regulation of apoptotic process CAPN3;ALB GO:0006508| proteolysis KLK1;CAPN3 29413:[DB06728 DB12200] DB06728|Aniline KLK1;ALB;CYP2E1 DB12200|Tivantinib MET common genes common pathways 29414:[DB06728 DB06366] DB06728|Aniline KLK1;ALB;CYP2E1 DB06366|Pertuzumab ERBB2 common genes common pathways 29415:[DB06728 DB04590] DB06728|Aniline KLK1;ALB;CYP2E1 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways GO:0006508| proteolysis KLK1;F7 29416:[DB06728 DB05668] DB06728|Aniline KLK1;ALB;CYP2E1 DB05668|Palifosfamide DNMT1 common genes common pathways 29417:[DB06728 DB04758] DB06728|Aniline KLK1;ALB;CYP2E1 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0006508| proteolysis KLK1;F7 29418:[DB06728 DB05404] DB06728|Aniline KLK1;ALB;CYP2E1 DB05404|AZD 3355 TP53 common genes common pathways GO:0045471| response to ethanol TP53;CYP2E1 GO:0043066| negative regulation of apoptotic process TP53;ALB GO:0010243| response to organic nitrogen TP53;CYP2E1 GO:0042493| response to drug CYP2E1;TP53 29419:[DB06728 DB06101] DB06728|Aniline KLK1;ALB;CYP2E1 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways GO:0043066| negative regulation of apoptotic process FLT4;KDR;ALB 29420:[DB06728 DB03691] DB06728|Aniline KLK1;ALB;CYP2E1 DB03691|WRR-112 CTSF common genes common pathways GO:0006508| proteolysis KLK1;CTSF 29421:[DB06728 DB04461] DB06728|Aniline KLK1;ALB;CYP2E1 DB04461|Coproporphyrinogen III UROD common genes common pathways 29422:[DB06728 DB07039] DB06728|Aniline KLK1;ALB;CYP2E1 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways 29423:[DB06728 DB11059] DB06728|Aniline KLK1;ALB;CYP2E1 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways 29424:[DB06728 DB04325] DB06728|Aniline KLK1;ALB;CYP2E1 DB04325|Phenethylamine PRSS2;PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;PRSS2;KLK1 29425:[DB06728 DB06973] DB06728|Aniline KLK1;ALB;CYP2E1 DB06973|4,4'-PROPANE-2,2-DIYLDIPHENOL ESRRG common genes common pathways 29426:[DB06728 DB04238] DB06728|Aniline KLK1;ALB;CYP2E1 DB04238|N-Alpha-(2-Naphthylsulfonyl)-N-(3-Amidino-L-Phenylalaninyl)-D-Pipecolinic Acid PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29427:[DB06728 DB03403] DB06728|Aniline KLK1;ALB;CYP2E1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 29428:[DB06728 DB00685] DB06728|Aniline KLK1;ALB;CYP2E1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 29429:[DB06728 DB02712] DB06728|Aniline KLK1;ALB;CYP2E1 DB02712|Sorbinil AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 29430:[DB06728 DB06237] DB06728|Aniline KLK1;ALB;CYP2E1 DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 29431:[DB06728 DB08497] DB06728|Aniline KLK1;ALB;CYP2E1 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0006508| proteolysis KLK1;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0042493| response to drug CASP3;CYP2E1 29432:[DB06728 DB08155] DB06728|Aniline KLK1;ALB;CYP2E1 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways 29433:[DB06728 DB04109] DB06728|Aniline KLK1;ALB;CYP2E1 DB04109|[4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]Benzamidine PRSS3 common genes common pathways GO:0006508| proteolysis KLK1;PRSS3 29434:[DB06728 DB07428] DB06728|Aniline KLK1;ALB;CYP2E1 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBA1;HBB GO:0098869| HBB;HBA1;ALB 29435:[DB06728 DB04074] DB06728|Aniline KLK1;ALB;CYP2E1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 29436:[DB06728 DB02180] DB06728|Aniline KLK1;ALB;CYP2E1 DB02180|Myristoyl-Coa NMT1;NMT2 common genes common pathways 29437:[DB06728 DB03239] DB06728|Aniline KLK1;ALB;CYP2E1 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 29438:[DB06728 DB02354] DB06728|Aniline KLK1;ALB;CYP2E1 DB02354|4-{[1-Methyl-5-(2-Methyl-Benzoimidazol-1-Ylmethyl)-1h-Benzoimidazol-2-Ylmethyl]-Amino}-Benzamidine PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 29439:[DB06728 DB01102] DB06728|Aniline KLK1;ALB;CYP2E1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 29440:[DB06728 DB04843] DB06728|Aniline KLK1;ALB;CYP2E1 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways 29441:[DB06728 DB07548] DB06728|Aniline KLK1;ALB;CYP2E1 DB07548|2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 29442:[DB06728 DB07067] DB06728|Aniline KLK1;ALB;CYP2E1 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 29443:[DB06728 DB05191] DB06728|Aniline KLK1;ALB;CYP2E1 DB05191|Atl146e ADORA2A common genes common pathways GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0042493| response to drug ADORA2A;CYP2E1 29444:[DB06728 DB01834] DB06728|Aniline KLK1;ALB;CYP2E1 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0098869| ALB;GSTP1 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2E1 29445:[DB06728 DB00859] DB06728|Aniline KLK1;ALB;CYP2E1 DB00859|Penicillamine SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB 29446:[DB06728 DB12458] DB06728|Aniline KLK1;ALB;CYP2E1 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways 29447:[DB06728 DB11703] DB06728|Aniline KLK1;ALB;CYP2E1 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP2E1;CYP3A7;CYP3A43 29448:[DB06728 DB00655] DB06728|Aniline KLK1;ALB;CYP2E1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes CYP2E1;ALB common pathways GO:0018910| benzene metabolic process CYP2E1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2B6;CYP1B1;CYP2E1;CYP1A2;CYP4A11 GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;CYP2B6;CYP19A1;CYP1A1;CYP2C9;CYP4A11;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;CYP1A1;ABCB1;ABCG2 GO:0010243| response to organic nitrogen CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;SLCO1B1;ALB;SLCO2B1 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A5;CYP1B1;CYP2B6;CYP2C9;CYP1A1;CYP3A4;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2B6;CYP1A1;CYP2C9 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1B1;SLCO1A2 GO:0010193| response to ozone CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A5;CYP1B1;CYP2B6;CYP2C9 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 29449:[DB06728 DB03268] DB06728|Aniline KLK1;ALB;CYP2E1 DB03268|RU82197 SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process SRC;ALB 29450:[DB06728 DB03225] DB06728|Aniline KLK1;ALB;CYP2E1 DB03225|D-Tryptophan DAO;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DAO 29451:[DB06728 DB06911] DB06728|Aniline KLK1;ALB;CYP2E1 DB06911|D-leucyl-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 29452:[DB06728 DB00902] DB06728|Aniline KLK1;ALB;CYP2E1 DB00902|Methdilazine HRH1 common genes common pathways 29453:[DB06728 DB03593] DB06728|Aniline KLK1;ALB;CYP2E1 DB03593|N7-Methyl-Guanosine-5'-Monophosphate DCPS common genes common pathways GO:0043069| negative regulation of programmed cell death ALB;DCPS 29454:[DB06728 DB00696] DB06728|Aniline KLK1;ALB;CYP2E1 DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug HTR2A;CYP2E1;DRD1;SLC6A2;DRD2;ADRA1A;ABCB1;HTR1B;HTR2C;HTR2B GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol DRD2;HTR1B;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 29455:[DB06728 DB05087] DB06728|Aniline KLK1;ALB;CYP2E1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways 29456:[DB06728 DB04840] DB06728|Aniline KLK1;ALB;CYP2E1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A1;CYP2D6 GO:0042493| response to drug SLC6A2;CYP1A1;ABCB1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A1;CYP2D6 GO:0017144| drug metabolic process CYP1A1;CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 29457:[DB06728 DB04562] DB06728|Aniline KLK1;ALB;CYP2E1 DB04562|Tricarballylic Acid ACO2 common genes common pathways 29458:[DB06728 DB09304] DB06728|Aniline KLK1;ALB;CYP2E1 DB09304|Setiptiline ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7 common genes common pathways GO:0042493| response to drug HTR2C;HTR2B;HTR1B;CYP2E1;HTR2A GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0045471| response to ethanol CYP2E1;HTR1B;HTR3A 29459:[DB06728 DB00886] DB06728|Aniline KLK1;ALB;CYP2E1 DB00886|Omapatrilat ACE;MME common genes common pathways GO:0006508| proteolysis ACE;KLK1;MME 29460:[DB06728 DB08557] DB06728|Aniline KLK1;ALB;CYP2E1 DB08557|2-[(2-methoxyethyl)amino]-4-(4-oxo-1,2,3,4-tetrahydro-9H-carbazol-9-yl)benzamide HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 29461:[DB06728 DB01626] DB06728|Aniline KLK1;ALB;CYP2E1 DB01626|Pargyline MAOB;MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOB;MAOA;CYP2E1 GO:0042493| response to drug MAOB;CYP2E1 GO:0045471| response to ethanol CYP2E1;MAOB 29462:[DB06728 DB08062] DB06728|Aniline KLK1;ALB;CYP2E1 DB08062|3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 29463:[DB06728 DB05351] DB06728|Aniline KLK1;ALB;CYP2E1 DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1 GO:0010243| response to organic nitrogen ATP4B;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19 29464:[DB06728 DB14642] DB06728|Aniline KLK1;ALB;CYP2E1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0042493| response to drug ABCC2;CYP2E1 29465:[DB06728 DB00635] DB06728|Aniline KLK1;ALB;CYP2E1 DB00635|Prednisone NR3C1;HSD11B1;CYP3A4;CYP2C19;ALB;ABCB1;SLCO1A2 common genes ALB common pathways GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;HSD11B1;CYP2C19 GO:0042493| response to drug ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0008202| steroid metabolic process HSD11B1;CYP2E1;CYP3A4;CYP2C19 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 29466:[DB06728 DB04865] DB06728|Aniline KLK1;ALB;CYP2E1 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 29467:[DB06728 DB06536] DB06728|Aniline KLK1;ALB;CYP2E1 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 29468:[DB06728 DB01081] DB06728|Aniline KLK1;ALB;CYP2E1 DB01081|Diphenoxylate OPRM1;OPRD1 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1 29469:[DB06728 DB01219] DB06728|Aniline KLK1;ALB;CYP2E1 DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 29470:[DB06728 DB00845] DB06728|Aniline KLK1;ALB;CYP2E1 DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 29471:[DB06728 DB09065] DB06728|Aniline KLK1;ALB;CYP2E1 DB09065|Cobicistat CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2D6 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1B3 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP3A43;CYP3A7;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A5;CYP3A4;CYP2E1;CYP3A7 29472:[DB06728 DB09166] DB06728|Aniline KLK1;ALB;CYP2E1 DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2E1;CYP3A4;CYP2C18 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C18;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C18;CYP2E1;CYP3A4;CYP2C19 29473:[DB06728 DB08760] DB06728|Aniline KLK1;ALB;CYP2E1 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 29474:[DB06728 DB12945] DB06728|Aniline KLK1;ALB;CYP2E1 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 29475:[DB06728 DB04889] DB06728|Aniline KLK1;ALB;CYP2E1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0045471| response to ethanol CYP2E1;MAOB;DRD2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A4;MAOB;SLC6A2;DRD2 GO:0055114| oxidation-reduction process CYP2D6;MAOB;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 29476:[DB06728 DB00782] DB06728|Aniline KLK1;ALB;CYP2E1 DB00782|Propantheline CHRM1 common genes common pathways 29477:[DB06728 DB00422] DB06728|Aniline KLK1;ALB;CYP2E1 DB00422|Methylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A2;SLC6A3;CYP2E1;SLC6A4 GO:0045471| response to ethanol CYP2E1;SLC6A3 29478:[DB06728 DB07642] DB06728|Aniline KLK1;ALB;CYP2E1 DB07642|5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways GO:0043069| negative regulation of programmed cell death DCPS;ALB 29479:[DB06728 DB14508] DB06728|Aniline KLK1;ALB;CYP2E1 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0043066| negative regulation of apoptotic process GSK3B;ALB 29480:[DB06728 DB04872] DB06728|Aniline KLK1;ALB;CYP2E1 DB04872|Osanetant TACR3 common genes common pathways 29481:[DB06728 DB04187] DB06728|Aniline KLK1;ALB;CYP2E1 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways 29482:[DB06728 DB00502] DB06728|Aniline KLK1;ALB;CYP2E1 DB00502|Haloperidol DRD2;DRD1;GRIN2B;HTR2A;DRD3;MCHR1;SLC18A2;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP3A4;CBR1;UGT1A9;CYP1A1;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN2B;DRD3;DRD2 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C9;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CBR1;CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP3A5;CYP2D6;CYP2C19;CYP1A1;CYP2C9 GO:0042493| response to drug CYP1A1;DRD3;ABCB1;DRD2;CYP1A2;CYP2E1;HTR2A;DRD1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C19;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2C19;CYP2D6;CYP1A1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CBR1;CYP1A1;CYP2C9;UGT1A9;CYP2C19;CYP2D6 29483:[DB06728 DB01569] DB06728|Aniline KLK1;ALB;CYP2E1 DB01569|Formebolone HSD11B2 common genes common pathways GO:0042493| response to drug CYP2E1;HSD11B2 GO:0055114| oxidation-reduction process CYP2E1;HSD11B2 29484:[DB06728 DB03414] DB06728|Aniline KLK1;ALB;CYP2E1 DB03414|5-Thio-a/B-D-Mannopyranosylamine MAN2A1 common genes common pathways 29485:[DB06728 DB05434] DB06728|Aniline KLK1;ALB;CYP2E1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0002576| platelet degranulation ALB;HGF;VEGFA GO:0043066| negative regulation of apoptotic process VEGFA;HGF;ALB GO:0006508| proteolysis KLK1;HGF 29486:[DB06728 DB01008] DB06728|Aniline KLK1;ALB;CYP2E1 DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;MGST2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0098869| MGST2;GSTP1;GSTA1;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;MGST2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process GSTP1;ALB 29487:[DB06728 DB06731] DB06728|Aniline KLK1;ALB;CYP2E1 DB06731|Seproxetine CYP3A5;CYP3A7;CYP2C9;CYP2C19 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A7;CYP2C9;CYP3A5;CYP2C19 GO:0008202| steroid metabolic process CYP2C9;CYP3A5;CYP2C19;CYP3A7;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C9;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP2C19;CYP3A5;CYP2C9 29488:[DB06728 DB06784] DB06728|Aniline KLK1;ALB;CYP2E1 DB06784|Gallium citrate Ga 67 TFRC;TFR2;FTL;FTH1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;FTH1 GO:0006898| receptor-mediated endocytosis TFRC;TFR2;ALB 29489:[DB06728 DB04760] DB06728|Aniline KLK1;ALB;CYP2E1 DB04760|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways GO:0044267| cellular protein metabolic process ALB;MMP13 GO:0006508| proteolysis KLK1;MMP13 29490:[DB06728 DB06211] DB06728|Aniline KLK1;ALB;CYP2E1 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0006508| proteolysis KLK1;DPEP1 GO:0006805| xenobiotic metabolic process DPEP1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;DPEP1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 29491:[DB06728 DB05792] DB06728|Aniline KLK1;ALB;CYP2E1 DB05792|Arylacenamide SIGMAR1 common genes common pathways 29492:[DB06728 DB00517] DB06728|Aniline KLK1;ALB;CYP2E1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways 29493:[DB06728 DB08838] DB06728|Aniline KLK1;ALB;CYP2E1 DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;GRIN1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 29494:[DB06728 DB00131] DB06728|Aniline KLK1;ALB;CYP2E1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;ACSL1 GO:0042493| response to drug ACSL1;ADCY1;CREB1;CYP2E1 GO:0043066| negative regulation of apoptotic process PIM1;ALB;PRKAA1 GO:0008202| steroid metabolic process CYP2E1;PRKAA1 29495:[DB06728 DB00594] DB06728|Aniline KLK1;ALB;CYP2E1 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AOC1 GO:0042493| response to drug CYP2E1;AOC1 GO:0043066| negative regulation of apoptotic process ASIC2;ALB;SLC9A1 GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 GO:0006508| proteolysis PLAU;KLK1 GO:0006805| xenobiotic metabolic process CYP2E1;AOC1 29496:[DB06728 DB06288] DB06728|Aniline KLK1;ALB;CYP2E1 DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0045471| response to ethanol DRD2;DRD3;CYP2E1 GO:0042493| response to drug CYP2E1;HTR2A;DRD2;DRD3 29497:[DB06728 DB00569] DB06728|Aniline KLK1;ALB;CYP2E1 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways GO:0043687| post-translational protein modification SERPINC1;ALB GO:0044267| cellular protein metabolic process ALB;SERPINC1 GO:0006508| proteolysis F10;KLK1 29498:[DB06728 DB11358] DB06728|Aniline KLK1;ALB;CYP2E1 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways GO:0055114| oxidation-reduction process FADS2;FADS1;CYP2E1 GO:0009267| cellular response to starvation ALB;FADS1 29499:[DB06728 DB09205] DB06728|Aniline KLK1;ALB;CYP2E1 DB09205|Moxisylyte ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE;ADRA1A 29500:[DB06728 DB03059] DB06728|Aniline KLK1;ALB;CYP2E1 DB03059|Acetoacetyl-CoA HADH;ACADS;ECHS1 common genes common pathways GO:0042493| response to drug HADH;CYP2E1 GO:0055114| oxidation-reduction process ACADS;CYP2E1;HADH 29501:[DB06728 DB04066] DB06728|Aniline KLK1;ALB;CYP2E1 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways GO:0055114| oxidation-reduction process PTGR1;CYP2E1 29502:[DB06728 DB09282] DB06728|Aniline KLK1;ALB;CYP2E1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 29503:[DB06728 DB00630] DB06728|Aniline KLK1;ALB;CYP2E1 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 29504:[DB06728 DB02616] DB06728|Aniline KLK1;ALB;CYP2E1 DB02616|FR117016 ADA common genes common pathways GO:0042493| response to drug ADA;CYP2E1 GO:0043066| negative regulation of apoptotic process ADA;ALB 29505:[DB06728 DB00237] DB06728|Aniline KLK1;ALB;CYP2E1 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 29506:[DB06728 DB06098] DB06728|Aniline KLK1;ALB;CYP2E1 DB06098|PRLX 93936 VDAC2;VDAC3 common genes common pathways 29507:[DB06728 DB08326] DB06728|Aniline KLK1;ALB;CYP2E1 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways 29508:[DB06728 DB03349] DB06728|Aniline KLK1;ALB;CYP2E1 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways 29509:[DB06728 DB02872] DB06728|Aniline KLK1;ALB;CYP2E1 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways GO:0043066| negative regulation of apoptotic process MDM2;ALB GO:0042493| response to drug CYP2E1;MDM2 29510:[DB06728 DB08822] DB06728|Aniline KLK1;ALB;CYP2E1 DB08822|Azilsartan medoxomil AGTR1 common genes common pathways 29511:[DB06728 DB02837] DB06728|Aniline KLK1;ALB;CYP2E1 DB02837|O4-Sulfonylgalactose MBL2 common genes common pathways GO:0006508| proteolysis MBL2;KLK1 29512:[DB06728 DB11094] DB06728|Aniline KLK1;ALB;CYP2E1 DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP27B1;CYP2R1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 29513:[DB06728 DB05418] DB06728|Aniline KLK1;ALB;CYP2E1 DB05418|GW 597599 TACR1 common genes common pathways GO:0010193| response to ozone CYP2E1;TACR1 GO:0045471| response to ethanol CYP2E1;TACR1 29514:[DB06728 DB01080] DB06728|Aniline KLK1;ALB;CYP2E1 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0045471| response to ethanol ABAT;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0042493| response to drug CYP2E1;ABAT GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 29515:[DB06728 DB05218] DB06728|Aniline KLK1;ALB;CYP2E1 DB05218|PN0621 TNF common genes common pathways 29516:[DB06728 DB07976] DB06728|Aniline KLK1;ALB;CYP2E1 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP2E1 GO:0042493| response to drug DHODH;CYP2E1 29517:[DB06728 DB09053] DB06728|Aniline KLK1;ALB;CYP2E1 DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes ALB common pathways GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP3A5 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP3A5 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ORM1;ORM2;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB 29518:[DB06728 DB03791] DB06728|Aniline KLK1;ALB;CYP2E1 DB03791|(3-{3-[[2-Chloro-3-(Trifluoromethyl)Benzyl](2,2-Diphenylethyl)Amino]Propoxy}Phenyl)Acetic Acid NR1H2 common genes common pathways 29519:[DB06728 DB02499] DB06728|Aniline KLK1;ALB;CYP2E1 DB02499|Dinor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0042493| response to drug CYP2E1;ARG1 29520:[DB06728 DB00276] DB06728|Aniline KLK1;ALB;CYP2E1 DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ORM1;ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;ABCB1 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 29521:[DB06728 DB02109] DB06728|Aniline KLK1;ALB;CYP2E1 DB02109|Hadacidin purA;ADSSL1 common genes common pathways 29522:[DB06728 DB03415] DB06728|Aniline KLK1;ALB;CYP2E1 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways GO:0055114| oxidation-reduction process ACADM;CYP2E1 29523:[DB06728 DB05408] DB06728|Aniline KLK1;ALB;CYP2E1 DB05408|Emricasan CASP1;CASP3;CASP7 common genes common pathways GO:0042493| response to drug CYP2E1;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0006508| proteolysis CASP1;CASP7;CASP3;KLK1 29524:[DB06728 DB06999] DB06728|Aniline KLK1;ALB;CYP2E1 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways GO:0043066| negative regulation of apoptotic process BRAF;ALB 29525:[DB06728 DB07435] DB06728|Aniline KLK1;ALB;CYP2E1 DB07435|1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE POLK;polA common genes common pathways 29526:[DB06728 DB14018] DB06728|Aniline KLK1;ALB;CYP2E1 DB14018|Bromotheophylline CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 29527:[DB06728 DB03240] DB06728|Aniline KLK1;ALB;CYP2E1 DB03240|(S)-2-Amino-3-(1,3,5,7-Pentahydro-2,4-Dioxo-Cyclopenta[E]Pyrimidin-1-Yl) Proionic Acid GRIA2 common genes common pathways 29528:[DB06728 DB00405] DB06728|Aniline KLK1;ALB;CYP2E1 DB00405|Dexbrompheniramine HRH1 common genes common pathways 29529:[DB06728 DB00346] DB06728|Aniline KLK1;ALB;CYP2E1 DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ADRA1A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 29530:[DB06728 DB04883] DB06728|Aniline KLK1;ALB;CYP2E1 DB04883|Darusentan EDNRA common genes common pathways 29531:[DB06728 DB00878] DB06728|Aniline KLK1;ALB;CYP2E1 DB00878|Chlorhexidine HNMT;cat common genes common pathways 29532:[DB06728 DB09265] DB06728|Aniline KLK1;ALB;CYP2E1 DB09265|Lixisenatide GLP1R common genes common pathways 29533:[DB06728 DB11586] DB06728|Aniline KLK1;ALB;CYP2E1 DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2D6;CYP3A7;CYP2E1;CYP3A4;CYP2A6;CYP3A43 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP2B6;CYP2C9;CYP2C19 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;ALB;SLCO2B1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6;CYP2C9;CYP2B6;CYP2D6;CYP2C19 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1B3;SLCO1B1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2A6;CYP3A7;CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP2B6;CYP2C9;CYP3A7;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 29534:[DB06728 DB07621] DB06728|Aniline KLK1;ALB;CYP2E1 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2A6 GO:0017144| drug metabolic process CYP2E1;CYP2A6 GO:0055114| oxidation-reduction process CYP2A6;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6 29535:[DB06728 DB11429] DB06728|Aniline KLK1;ALB;CYP2E1 DB11429|Mibolerone AR common genes common pathways 29536:[DB06728 DB08305] DB06728|Aniline KLK1;ALB;CYP2E1 DB08305|(3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide GRIA2 common genes common pathways 29537:[DB06728 DB00675] DB06728|Aniline KLK1;ALB;CYP2E1 DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes CYP2E1 common pathways GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0045471| response to ethanol CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;FMO1;CYP3A4;CES1;CYP3A7;CYP2C9;CYP2B6;FMO3;NR1I2;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1B1;SULT1A1 GO:0008202| steroid metabolic process NR1I2;CYP2B6;CYP2C9;CYP1A1;SULT1A1;CYP1B1;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP3A7;CYP2A6;CYP3A4;CYP2E1;EBP GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2B6;CYP2C9;CYP1A1;UGT1A10;CYP2A6;FMO1;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0010193| response to ozone CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP2C9;CYP1A1;CYP2B6;CYP2C19;CYP2C8;CYP1B1 GO:0043066| negative regulation of apoptotic process PRKCI;PRKCZ;ALB GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug CYP1A1;ABCC2;ABCG2;ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A7;CYP2A6;CYP3A4;FMO1;CYP2E1;CYP1B1;CYP2D6;CYP2C8;CYP2C19;CYP3A5;FMO3;CYP2B6;CYP19A1;CYP2C9;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1 29538:[DB06728 DB14065] DB06728|Aniline KLK1;ALB;CYP2E1 DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 29539:[DB06728 DB05466] DB06728|Aniline KLK1;ALB;CYP2E1 DB05466|R673 TACR1 common genes common pathways GO:0045471| response to ethanol CYP2E1;TACR1 GO:0010193| response to ozone TACR1;CYP2E1 29540:[DB06728 DB05752] DB06728|Aniline KLK1;ALB;CYP2E1 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 29541:[DB06728 DB07804] DB06728|Aniline KLK1;ALB;CYP2E1 DB07804|5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 29542:[DB06728 DB04805] DB06728|Aniline KLK1;ALB;CYP2E1 DB04805|Virginiamycin S1 RPL37 common genes common pathways 29543:[DB06728 DB06460] DB06728|Aniline KLK1;ALB;CYP2E1 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways GO:0043066| negative regulation of apoptotic process EDNRB;ALB 29544:[DB06728 DB07742] DB06728|Aniline KLK1;ALB;CYP2E1 DB07742|N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE CA2 common genes common pathways 29545:[DB06728 DB02535] DB06728|Aniline KLK1;ALB;CYP2E1 DB02535|Aminodi(Ethyloxy)Ethylaminocarbonylbenzenesulfonamide CA2 common genes common pathways 29546:[DB06728 DB01019] DB06728|Aniline KLK1;ALB;CYP2E1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways 29547:[DB06728 DB13800] DB06728|Aniline KLK1;ALB;CYP2E1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0002576| platelet degranulation ALB;CALM1 29548:[DB06728 DB03337] DB06728|Aniline KLK1;ALB;CYP2E1 DB03337|1-(2-Amidinophenyl)-3-(Phenoxyphenyl)Urea PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29549:[DB06728 DB04527] DB06728|Aniline KLK1;ALB;CYP2E1 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways GO:0006508| proteolysis KLK1;MASP2 29550:[DB06728 DB08491] DB06728|Aniline KLK1;ALB;CYP2E1 DB08491|N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE MMP1 common genes common pathways GO:0006508| proteolysis KLK1;MMP1 GO:0044267| cellular protein metabolic process MMP1;ALB 29551:[DB06728 DB08613] DB06728|Aniline KLK1;ALB;CYP2E1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0042493| response to drug HDAC4;CYP2E1 29552:[DB06728 DB03024] DB06728|Aniline KLK1;ALB;CYP2E1 DB03024|2-Methyl-3-(2-Aminothiazolo)Propanal REN common genes common pathways GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug REN;CYP2E1 29553:[DB06728 DB01496] DB06728|Aniline KLK1;ALB;CYP2E1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 29554:[DB06728 DB05194] DB06728|Aniline KLK1;ALB;CYP2E1 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways GO:0044267| cellular protein metabolic process ALB;CSF2RA 29555:[DB06728 DB11699] DB06728|Aniline KLK1;ALB;CYP2E1 DB11699|Tropisetron HTR3A common genes common pathways GO:0045471| response to ethanol HTR3A;CYP2E1 29556:[DB06728 DB04948] DB06728|Aniline KLK1;ALB;CYP2E1 DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2;CYP2C19;CYP2D6 GO:0042493| response to drug CYP2E1;CYP1A2;HTR2C;ADRA1A GO:0055114| oxidation-reduction process CYP2E1;CYP1A2;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C19 29557:[DB06728 DB11637] DB06728|Aniline KLK1;ALB;CYP2E1 DB11637|Delamanid CYP3A4;ALB;ORM1 common genes ALB common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB;ORM1 GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 29558:[DB06728 DB07384] DB06728|Aniline KLK1;ALB;CYP2E1 DB07384|1-ACETYL-2-CARBOXYPIPERIDINE ATP5B common genes common pathways 29559:[DB06728 DB13994] DB06728|Aniline KLK1;ALB;CYP2E1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 29560:[DB06728 DB07712] DB06728|Aniline KLK1;ALB;CYP2E1 DB07712|3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 29561:[DB06728 DB07798] DB06728|Aniline KLK1;ALB;CYP2E1 DB07798|(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 29562:[DB06728 DB00414] DB06728|Aniline KLK1;ALB;CYP2E1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes ALB common pathways GO:0017144| drug metabolic process CYP2E1;CBR1;CYP2C9 GO:0098869| ALB GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CBR1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 29563:[DB06728 DB02670] DB06728|Aniline KLK1;ALB;CYP2E1 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways 29564:[DB06728 DB02755] DB06728|Aniline KLK1;ALB;CYP2E1 DB02755|1-3 Sugar Ring of Pentamannosyl 6-Phosphate M6PR common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;M6PR 29565:[DB06728 DB00565] DB06728|Aniline KLK1;ALB;CYP2E1 DB00565|Cisatracurium CHRNA2 common genes common pathways 29566:[DB06728 DB06925] DB06728|Aniline KLK1;ALB;CYP2E1 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways GO:0042493| response to drug CYP2E1;LCK 29567:[DB06728 DB08502] DB06728|Aniline KLK1;ALB;CYP2E1 DB08502|Capravirine CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 29568:[DB06728 DB05685] DB06728|Aniline KLK1;ALB;CYP2E1 DB05685|FX06 CDH5 common genes common pathways 29569:[DB06728 DB00989] DB06728|Aniline KLK1;ALB;CYP2E1 DB00989|Rivastigmine ACHE;BCHE;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug BCHE;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 29570:[DB06728 DB00494] DB06728|Aniline KLK1;ALB;CYP2E1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP2E1;COMT GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;UGT1A9;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 29571:[DB06728 DB01548] DB06728|Aniline KLK1;ALB;CYP2E1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 29572:[DB06728 DB06148] DB06728|Aniline KLK1;ALB;CYP2E1 DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0042493| response to drug SLC6A4;DRD1;CYP1A2;CYP2E1;HTR2A;ADRA1A;DRD2;HTR2B;HTR2C;SLC6A3;SLC6A2;DRD3 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2B6;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2B6 GO:0008202| steroid metabolic process CYP2D6;CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2B6;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol CYP2E1;DRD2;OPRK1;SLC6A3;DRD3 29573:[DB06728 DB06996] DB06728|Aniline KLK1;ALB;CYP2E1 DB06996|D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 29574:[DB06728 DB12093] DB06728|Aniline KLK1;ALB;CYP2E1 DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug DRD2;CYP2E1;DRD1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol DRD2;CYP2E1 29575:[DB06728 DB11256] DB06728|Aniline KLK1;ALB;CYP2E1 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways 29576:[DB06728 DB00315] DB06728|Aniline KLK1;ALB;CYP2E1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;MAOA;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;HTR1B GO:0045471| response to ethanol HTR1B;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 29577:[DB06728 DB08224] DB06728|Aniline KLK1;ALB;CYP2E1 DB08224|(1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 29578:[DB06728 DB11064] DB06728|Aniline KLK1;ALB;CYP2E1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways 29579:[DB06728 DB03152] DB06728|Aniline KLK1;ALB;CYP2E1 DB03152|B-2-Octylglucoside polA;aqpZ;TGM3;aqpZ;petB;petA;RHO common genes common pathways 29580:[DB06728 DB05044] DB06728|Aniline KLK1;ALB;CYP2E1 DB05044|PSN357 PYGL common genes common pathways 29581:[DB06728 DB03926] DB06728|Aniline KLK1;ALB;CYP2E1 DB03926|5-Alpha-Androstane-3-Beta,17-Alpha-Diol SHBG common genes common pathways 29582:[DB06728 DB07720] DB06728|Aniline KLK1;ALB;CYP2E1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0045471| response to ethanol CYP2E1;CHRNB2 29583:[DB06728 DB07694] DB06728|Aniline KLK1;ALB;CYP2E1 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 29584:[DB06728 DB05201] DB06728|Aniline KLK1;ALB;CYP2E1 DB05201|V24343 CNR1 common genes common pathways GO:0045471| response to ethanol CYP2E1;CNR1 29585:[DB06728 DB05451] DB06728|Aniline KLK1;ALB;CYP2E1 DB05451|P54 NFKB2;NFKB1 common genes common pathways GO:0043066| negative regulation of apoptotic process NFKB1;ALB 29586:[DB06728 DB03566] DB06728|Aniline KLK1;ALB;CYP2E1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0098869| TXNRD1;ALB GO:0055114| oxidation-reduction process CYP2E1;TXNRD1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 29587:[DB06728 DB09331] DB06728|Aniline KLK1;ALB;CYP2E1 DB09331|Daratumumab CD38 common genes common pathways GO:0042493| response to drug CD38;CYP2E1 GO:0043066| negative regulation of apoptotic process CD38;ALB 29588:[DB06728 DB01337] DB06728|Aniline KLK1;ALB;CYP2E1 DB01337|Pancuronium CHRNA2;CHRM2;CHRM3;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 29589:[DB06728 DB06111] DB06728|Aniline KLK1;ALB;CYP2E1 DB06111|AB192 MPO common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0055114| oxidation-reduction process MPO;CYP2E1 29590:[DB06728 DB01992] DB06728|Aniline KLK1;ALB;CYP2E1 DB01992|Coenzyme A acs;DBI;CRAT;glcB;coaD;acpS;HMGCR;KAT5;dapD;ACAT2;vatD;CS;fabH;coaA;fabH;KAT2A;KAT2B;cysE;gltA;glmU common genes common pathways GO:0045471| response to ethanol HMGCR;CYP2E1 GO:0008202| steroid metabolic process HMGCR;CYP2E1 GO:0055114| oxidation-reduction process HMGCR;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;HMGCR 29591:[DB06728 DB00008] DB06728|Aniline KLK1;ALB;CYP2E1 DB00008|Peginterferon alfa-2a IFNAR2;IFNAR1;CYP1A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 29592:[DB06728 DB04432] DB06728|Aniline KLK1;ALB;CYP2E1 DB04432|ZK-805623 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29593:[DB06728 DB04783] DB06728|Aniline KLK1;ALB;CYP2E1 DB04783|Sphinxolide B ACTA1 common genes common pathways 29594:[DB06728 DB01074] DB06728|Aniline KLK1;ALB;CYP2E1 DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;CPT1A GO:0006805| xenobiotic metabolic process CYP2D6;CYP2B6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2B6 GO:0008202| steroid metabolic process CYP2B6;CYP2D6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0042493| response to drug CPT1A;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2B6 29595:[DB06728 DB01977] DB06728|Aniline KLK1;ALB;CYP2E1 DB01977|6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 29596:[DB06728 DB04915] DB06728|Aniline KLK1;ALB;CYP2E1 DB04915|Idronoxil ENOX2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ENOX2 29597:[DB06728 DB04997] DB06728|Aniline KLK1;ALB;CYP2E1 DB04997|ATL1102 ITGA4 common genes common pathways 29598:[DB06728 DB05091] DB06728|Aniline KLK1;ALB;CYP2E1 DB05091|M0002 AVPR2 common genes common pathways 29599:[DB06728 DB00704] DB06728|Aniline KLK1;ALB;CYP2E1 DB00704|Naltrexone OPRD1;OPRM1;OPRK1;SIGMAR1;UGT1A1 common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1;CYP2E1;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1 29600:[DB06728 DB00018] DB06728|Aniline KLK1;ALB;CYP2E1 DB00018|Interferon alfa-n3 IFNAR1;IFNAR2 common genes common pathways 29601:[DB06728 DB04107] DB06728|Aniline KLK1;ALB;CYP2E1 DB04107|[(1-{2[(4-Carbamimidoyl-Phenylamino)-Methyl]-1-Methyl-1h-Benzoimidazol-5-Yl}-Cyclopropyl)-Pyridin-2-Yl-Methyleneaminooxy]-Acetic Acid Ethyl Ester PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 29602:[DB06728 DB07334] DB06728|Aniline KLK1;ALB;CYP2E1 DB07334|N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB 29603:[DB06728 DB08172] DB06728|Aniline KLK1;ALB;CYP2E1 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP2E1 GO:0042493| response to drug CYP2E1;DHODH 29604:[DB06728 DB00790] DB06728|Aniline KLK1;ALB;CYP2E1 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis ACE;KLK1 GO:0042493| response to drug CYP2E1;BCHE 29605:[DB06728 DB01962] DB06728|Aniline KLK1;ALB;CYP2E1 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways GO:0043069| negative regulation of programmed cell death KIT;ALB GO:0043066| negative regulation of apoptotic process ALB;SRC;HCK GO:0042493| response to drug SRC;CYP2E1 29606:[DB06728 DB01835] DB06728|Aniline KLK1;ALB;CYP2E1 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 29607:[DB06728 DB03419] DB06728|Aniline KLK1;ALB;CYP2E1 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DPYD 29608:[DB06728 DB01296] DB06728|Aniline KLK1;ALB;CYP2E1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes CYP2E1 common pathways GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1 GO:0042493| response to drug CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0043066| negative regulation of apoptotic process MMP9;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;CYP2E1 GO:0006508| proteolysis KLK1;MMP9 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 29609:[DB06728 DB12866] DB06728|Aniline KLK1;ALB;CYP2E1 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;ALB 29610:[DB06728 DB02974] DB06728|Aniline KLK1;ALB;CYP2E1 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6 GO:0017144| drug metabolic process CYP2E1;CYP2B6 GO:0008202| steroid metabolic process CYP2E1;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2B6 29611:[DB06728 DB00849] DB06728|Aniline KLK1;ALB;CYP2E1 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C19;NR1I2;CYP2B6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2B6 GO:0055114| oxidation-reduction process CYP2B6;CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2B6;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;NR1I2;CYP2B6;CYP2E1 29612:[DB06728 DB01412] DB06728|Aniline KLK1;ALB;CYP2E1 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes CYP2E1 common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ADORA1;ALB GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug ADORA2A;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0010243| response to organic nitrogen CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0010193| response to ozone CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 29613:[DB06728 DB04674] DB06728|Aniline KLK1;ALB;CYP2E1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0055114| oxidation-reduction process AKR1C1;CYP2E1 GO:0015721| bile acid and bile salt transport AKR1C1;ALB GO:0044267| cellular protein metabolic process ALB;TTR GO:0006805| xenobiotic metabolic process CYP2E1;AKR1C1 29614:[DB06728 DB13150] DB06728|Aniline KLK1;ALB;CYP2E1 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways GO:0006508| proteolysis KLK1;F10;F9 29615:[DB06728 DB04827] DB06728|Aniline KLK1;ALB;CYP2E1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;AOX1 GO:0055114| oxidation-reduction process MPO;CYP2E1;AOX1 GO:0043066| negative regulation of apoptotic process MPO;ALB 29616:[DB06728 DB00521] DB06728|Aniline KLK1;ALB;CYP2E1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 29617:[DB06728 DB06842] DB06728|Aniline KLK1;ALB;CYP2E1 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways 29618:[DB06728 DB00531] DB06728|Aniline KLK1;ALB;CYP2E1 DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP2B6;CYP3A5;CYP2C8;CYP2C19;CYP3A4;CYP2E1;CYP2C18 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C9;CYP2C19;CYP2C8;CYP2A6;CYP2E1;CYP2C18 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP3A5;CYP2A6;CYP3A4;CYP2E1;CYP2C18 GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP2C19;CYP2C8;CYP2A6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP3A5;CYP2B6;NR1I2;CYP2C9 29619:[DB06728 DB05419] DB06728|Aniline KLK1;ALB;CYP2E1 DB05419|ADX-10061 CALY common genes common pathways 29620:[DB06728 DB07695] DB06728|Aniline KLK1;ALB;CYP2E1 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 29621:[DB06728 DB07851] DB06728|Aniline KLK1;ALB;CYP2E1 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 29622:[DB06728 DB09296] DB06728|Aniline KLK1;ALB;CYP2E1 DB09296|Ombitasvir CYP2C8;ABCB1;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C8 GO:0042493| response to drug CYP2E1;ABCG2;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2E1 29623:[DB06728 DB06700] DB06728|Aniline KLK1;ALB;CYP2E1 DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;SLC6A4;SLC6A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 29624:[DB06728 DB06782] DB06728|Aniline KLK1;ALB;CYP2E1 DB06782|Dimercaprol APP common genes common pathways GO:0002576| platelet degranulation ALB;APP GO:0043687| post-translational protein modification APP;ALB GO:0044267| cellular protein metabolic process ALB;APP 29625:[DB06728 DB00852] DB06728|Aniline KLK1;ALB;CYP2E1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug SLC6A3;ADRA1A;FOS;SLC6A2;SLC6A4;CYP2E1;JUN GO:0055114| oxidation-reduction process CYP2E1;MAOA;CYP2D6 GO:0043066| negative regulation of apoptotic process JUN;ATF5;IL2;ALB GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0045471| response to ethanol SLC6A3;IL2;CYP2E1 29626:[DB06728 DB03083] DB06728|Aniline KLK1;ALB;CYP2E1 DB03083|IC261 CSNK1G2 common genes common pathways 29627:[DB06728 DB07765] DB06728|Aniline KLK1;ALB;CYP2E1 DB07765|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHRS4L1 29628:[DB06728 DB02773] DB06728|Aniline KLK1;ALB;CYP2E1 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0098869| PTGS1;ALB GO:0055114| oxidation-reduction process CYP2E1;PTGS1 29629:[DB06728 DB06769] DB06728|Aniline KLK1;ALB;CYP2E1 DB06769|Bendamustine CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 29630:[DB06728 DB05022] DB06728|Aniline KLK1;ALB;CYP2E1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways 29631:[DB06728 DB06972] DB06728|Aniline KLK1;ALB;CYP2E1 DB06972|7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile ITGAL common genes common pathways 29632:[DB06728 DB00192] DB06728|Aniline KLK1;ALB;CYP2E1 DB00192|Indecainide SCN5A common genes common pathways 29633:[DB06728 DB00534] DB06728|Aniline KLK1;ALB;CYP2E1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ALDH5A1 29634:[DB06728 DB02215] DB06728|Aniline KLK1;ALB;CYP2E1 DB02215|Furoyl-Leucine ADAM28 common genes common pathways GO:0006508| proteolysis KLK1;ADAM28 29635:[DB06728 DB08299] DB06728|Aniline KLK1;ALB;CYP2E1 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways 29636:[DB06728 DB00229] DB06728|Aniline KLK1;ALB;CYP2E1 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A8 29637:[DB06728 DB05210] DB06728|Aniline KLK1;ALB;CYP2E1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0009267| cellular response to starvation ALB;MTOR GO:0043066| negative regulation of apoptotic process PRKDC;ALB;PIK3R1 29638:[DB06728 DB01588] DB06728|Aniline KLK1;ALB;CYP2E1 DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug GABRG3;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 29639:[DB06728 DB00963] DB06728|Aniline KLK1;ALB;CYP2E1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;PTGS1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0098869| PTGS2;PTGS1;ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 29640:[DB06728 DB07872] DB06728|Aniline KLK1;ALB;CYP2E1 DB07872|5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 29641:[DB06728 DB00574] DB06728|Aniline KLK1;ALB;CYP2E1 DB00574|Fenfluramine SLC6A4;HTR2B;HTR2C;HTR2A;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0042493| response to drug SLC6A4;CYP2E1;HTR2A;HTR2B;HTR2C GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 29642:[DB06728 DB01819] DB06728|Aniline KLK1;ALB;CYP2E1 DB01819|Phosphoenolpyruvate aroG;kdsA;ENO3;PCK1;kdsA;SLCO2A1 common genes common pathways GO:0042493| response to drug CYP2E1;ENO3 GO:0043252| sodium-independent organic anion transport ALB;SLCO2A1 29643:[DB06728 DB00396] DB06728|Aniline KLK1;ALB;CYP2E1 DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2A6;CYP3A7;CYP17A1;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1B1;CYP2C9;CYP1A1;NR1I2 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP2A6;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;ALB;SLC10A1 GO:0002576| platelet degranulation ORM1;ALB GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C8;CYP2C19;CYP1B1;CYP2A6;CYP2E1 GO:0042493| response to drug CYP2E1;ABCG2;ABCB1;CYP1A1;ABCC1 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2E1;CYP3A7;CYP2D6;CYP2C8;CYP2C19;CYP17A1;CYP3A5;CYP1B1;CYP2C9;CYP1A1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0045471| response to ethanol CYP2E1;OPRK1 GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1B1;CYP2E1;CYP3A4;CYP3A7 29644:[DB06728 DB02803] DB06728|Aniline KLK1;ALB;CYP2E1 DB02803|3-Phenyl-1,2-Propandiol REN common genes common pathways GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug REN;CYP2E1 29645:[DB06728 DB05305] DB06728|Aniline KLK1;ALB;CYP2E1 DB05305|Cintredekin Besudotox IL13 common genes common pathways GO:0045471| response to ethanol IL13;CYP2E1 29646:[DB06728 DB01871] DB06728|Aniline KLK1;ALB;CYP2E1 DB01871|[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways GO:0006508| proteolysis CTSF;KLK1 29647:[DB06728 DB06138] DB06728|Aniline KLK1;ALB;CYP2E1 DB06138|IRL-1620 EDNRB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EDNRB 29648:[DB06728 DB07235] DB06728|Aniline KLK1;ALB;CYP2E1 DB07235|N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE PRKACA common genes common pathways 29649:[DB06728 DB00289] DB06728|Aniline KLK1;ALB;CYP2E1 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0045471| response to ethanol GRIN2B;CYP2E1;GRIN1;GRIN2A;GRIN3A;SLC6A3 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0042493| response to drug SLC6A3;SLC6A2;SLC6A4;GRIN2A;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 29650:[DB06728 DB06343] DB06728|Aniline KLK1;ALB;CYP2E1 DB06343|Teprotumumab IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process IGF1R;ALB 29651:[DB06728 DB00946] DB06728|Aniline KLK1;ALB;CYP2E1 DB00946|Phenprocoumon VKORC1;CYP2C8;CYP2C9;CYP3A4;ALB;ORM1 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0017144| drug metabolic process VKORC1;CYP2E1;CYP3A4;CYP2C9;CYP2C8 GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process VKORC1;CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0002576| platelet degranulation ALB;ORM1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB 29652:[DB06728 DB07963] DB06728|Aniline KLK1;ALB;CYP2E1 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 29653:[DB06728 DB11491] DB06728|Aniline KLK1;ALB;CYP2E1 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 29654:[DB06728 DB02635] DB06728|Aniline KLK1;ALB;CYP2E1 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways 29655:[DB06728 DB07467] DB06728|Aniline KLK1;ALB;CYP2E1 DB07467|4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide CA2 common genes common pathways 29656:[DB06728 DB06751] DB06728|Aniline KLK1;ALB;CYP2E1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways 29657:[DB06728 DB04926] DB06728|Aniline KLK1;ALB;CYP2E1 DB04926|Neramexane GRIN3A common genes common pathways GO:0045471| response to ethanol GRIN3A;CYP2E1 29658:[DB06728 DB07132] DB06728|Aniline KLK1;ALB;CYP2E1 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways 29659:[DB06728 DB01650] DB06728|Aniline KLK1;ALB;CYP2E1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 29660:[DB06728 DB03928] DB06728|Aniline KLK1;ALB;CYP2E1 DB03928|Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol CTH common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CTH 29661:[DB06728 DB05521] DB06728|Aniline KLK1;ALB;CYP2E1 DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes ALB common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1B1 GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1B1;ALB;SLCO2B1 GO:0002576| platelet degranulation ORM1;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A5 GO:0043687| post-translational protein modification ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 29662:[DB06728 DB07006] DB06728|Aniline KLK1;ALB;CYP2E1 DB07006|9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE WEE1 common genes common pathways 29663:[DB06728 DB01257] DB06728|Aniline KLK1;ALB;CYP2E1 DB01257|Eculizumab C5 common genes common pathways 29664:[DB06728 DB04392] DB06728|Aniline KLK1;ALB;CYP2E1 DB04392|Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] NQO1;azoR common genes common pathways GO:0055114| oxidation-reduction process NQO1;CYP2E1 GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0006805| xenobiotic metabolic process CYP2E1;NQO1 GO:0045471| response to ethanol CYP2E1;NQO1 29665:[DB06728 DB03611] DB06728|Aniline KLK1;ALB;CYP2E1 DB03611|L-2-amino-4-methoxy-cis-but-3-enoic acid MAT1A common genes common pathways 29666:[DB06728 DB00150] DB06728|Aniline KLK1;ALB;CYP2E1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC16A2;ALB GO:0055114| oxidation-reduction process IDO1;TPH2;TPH1;TDO2;CYP2E1 29667:[DB06728 DB02825] DB06728|Aniline KLK1;ALB;CYP2E1 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways 29668:[DB06728 DB02854] DB06728|Aniline KLK1;ALB;CYP2E1 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0006508| proteolysis IGHG2;KLK1 GO:0055114| oxidation-reduction process HSD17B11;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;SULT2A1 29669:[DB06728 DB06534] DB06728|Aniline KLK1;ALB;CYP2E1 DB06534|Thrombopoietin MPL common genes common pathways 29670:[DB06728 DB05166] DB06728|Aniline KLK1;ALB;CYP2E1 DB05166|APD668 GPR119 common genes common pathways 29671:[DB06728 DB12035] DB06728|Aniline KLK1;ALB;CYP2E1 DB12035|Sarecycline ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 29672:[DB06728 DB11577] DB06728|Aniline KLK1;ALB;CYP2E1 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;AHR GO:0042493| response to drug ADRA1A;CYP2E1 29673:[DB06728 DB01288] DB06728|Aniline KLK1;ALB;CYP2E1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 29674:[DB06728 DB04695] DB06728|Aniline KLK1;ALB;CYP2E1 DB04695|Farnesyl thiopyrophosphate ispU;GGPS1;MVK common genes common pathways GO:0008202| steroid metabolic process MVK;CYP2E1 29675:[DB06728 DB08827] DB06728|Aniline KLK1;ALB;CYP2E1 DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 29676:[DB06728 DB12077] DB06728|Aniline KLK1;ALB;CYP2E1 DB12077|Urelumab TNFRSF9 common genes common pathways 29677:[DB06728 DB06155] DB06728|Aniline KLK1;ALB;CYP2E1 DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CNR1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 29678:[DB06728 DB06274] DB06728|Aniline KLK1;ALB;CYP2E1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;CYP2E1 29679:[DB06728 DB06977] DB06728|Aniline KLK1;ALB;CYP2E1 DB06977|(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine PRKACA common genes common pathways 29680:[DB06728 DB07874] DB06728|Aniline KLK1;ALB;CYP2E1 DB07874|(6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis BACE1;KLK1 29681:[DB06728 DB11431] DB06728|Aniline KLK1;ALB;CYP2E1 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;CYP2E1;CYP3A7 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0017144| drug metabolic process CYP2E1;CYP3A4 29682:[DB06728 DB06292] DB06728|Aniline KLK1;ALB;CYP2E1 DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C9;UGT2B4;UGT1A9;CYP2E1;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CYP2D6;CYP3A4;CYP2E1;CYP2A6;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2A6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2A6;CYP1A2;UGT2B7;CYP2C9;CYP1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A9;CYP1A1;CYP2C9;CYP2D6;CYP1A2;CYP2A6;CYP2E1;CYP3A4 29683:[DB06728 DB05042] DB06728|Aniline KLK1;ALB;CYP2E1 DB05042|SGS518 HTR6 common genes common pathways 29684:[DB06728 DB00715] DB06728|Aniline KLK1;ALB;CYP2E1 DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2B6;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP2B6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C8;CYP2D6;CYP2B6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2B6;CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;HTR2A;CYP2E1;SLC6A4;SLC6A2;ABCB1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2C8;CYP2D6;CYP2B6;CYP2C9 29685:[DB06728 DB05688] DB06728|Aniline KLK1;ALB;CYP2E1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0042493| response to drug CYP2E1;SLC6A4;SLC6A2 29686:[DB06728 DB00567] DB06728|Aniline KLK1;ALB;CYP2E1 DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A8 GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 29687:[DB06728 DB04958] DB06728|Aniline KLK1;ALB;CYP2E1 DB04958|Epratuzumab CD22 common genes common pathways 29688:[DB06728 DB04166] DB06728|Aniline KLK1;ALB;CYP2E1 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways GO:0055114| oxidation-reduction process IL4I1;DAO;CYP2E1 29689:[DB06728 DB00047] DB06728|Aniline KLK1;ALB;CYP2E1 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IGF1R 29690:[DB06728 DB01483] DB06728|Aniline KLK1;ALB;CYP2E1 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19 29691:[DB06728 DB12890] DB06728|Aniline KLK1;ALB;CYP2E1 DB12890|Dihydrexidine DRD1 common genes common pathways GO:0042493| response to drug DRD1;CYP2E1 29692:[DB06728 DB00130] DB06728|Aniline KLK1;ALB;CYP2E1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0042493| response to drug CYP2E1;PPAT;CTPS1;PFAS GO:0002576| platelet degranulation ALB;F13A1 GO:0043066| negative regulation of apoptotic process ALB;ASNS GO:0017144| drug metabolic process CYP2E1;CAD GO:0009267| cellular response to starvation GLUL;ALB 29693:[DB06728 DB08413] DB06728|Aniline KLK1;ALB;CYP2E1 DB08413|METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER IGKC;ALPP common genes common pathways GO:0006508| proteolysis IGKC;KLK1 GO:0006898| receptor-mediated endocytosis ALB;IGKC GO:0001895| retina homeostasis ALB;IGKC 29694:[DB06728 DB06579] DB06728|Aniline KLK1;ALB;CYP2E1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 29695:[DB06728 DB00834] DB06728|Aniline KLK1;ALB;CYP2E1 DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes common pathways GO:0006508| proteolysis KLK1;KLK3 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP2C9;NR1I2;CYP3A5;CYP2C8;CYP2D6 GO:0044267| cellular protein metabolic process ALB;KLK3 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;NR1I2;CYP2C9;CYP2D6;CYP2C8;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C9;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C8;CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0042493| response to drug ABCC1;ABCB1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 29696:[DB06728 DB00459] DB06728|Aniline KLK1;ALB;CYP2E1 DB00459|Acitretin RXRA;RARA;RARB;RARG;RXRB;RXRG;RBP1;CYP26A1;ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process RARG;RARA;ALB;RARB GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP26A1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport RXRA;ALB GO:0045471| response to ethanol RARA;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP26A1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 29697:[DB06728 DB14069] DB06728|Aniline KLK1;ALB;CYP2E1 DB14069|ONT-093 ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 29698:[DB06728 DB07427] DB06728|Aniline KLK1;ALB;CYP2E1 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0098869| HBB;HBA1;ALB GO:0006898| receptor-mediated endocytosis ALB;HBA1;HBB 29699:[DB06728 DB03525] DB06728|Aniline KLK1;ALB;CYP2E1 DB03525|RU79073 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug CYP2E1;SRC 29700:[DB06728 DB00117] DB06728|Aniline KLK1;ALB;CYP2E1 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways 29701:[DB06728 DB03976] DB06728|Aniline KLK1;ALB;CYP2E1 DB03976|Phosphorylisopropane PRSS1;PRSS2;CTRB1;BCHE common genes common pathways GO:0006508| proteolysis PRSS2;PRSS1;CTRB1;KLK1 GO:0042493| response to drug BCHE;CYP2E1 29702:[DB06728 DB01551] DB06728|Aniline KLK1;ALB;CYP2E1 DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 29703:[DB06728 DB04472] DB06728|Aniline KLK1;ALB;CYP2E1 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways 29704:[DB06728 DB06749] DB06728|Aniline KLK1;ALB;CYP2E1 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO1B3;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B3 29705:[DB06728 DB00978] DB06728|Aniline KLK1;ALB;CYP2E1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug ABCC2;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 29706:[DB06728 DB06714] DB06728|Aniline KLK1;ALB;CYP2E1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways 29707:[DB06728 DB05034] DB06728|Aniline KLK1;ALB;CYP2E1 DB05034|Ularitide NPR1 common genes common pathways 29708:[DB06728 DB08210] DB06728|Aniline KLK1;ALB;CYP2E1 DB08210|2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE GCK common genes common pathways 29709:[DB06728 DB01463] DB06728|Aniline KLK1;ALB;CYP2E1 DB01463|Fencamfamine SLC6A3 common genes common pathways GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A3 29710:[DB06728 DB02610] DB06728|Aniline KLK1;ALB;CYP2E1 DB02610|N-(2,3,4,5,6-Pentaflouro-Benzyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways 29711:[DB06728 DB06603] DB06728|Aniline KLK1;ALB;CYP2E1 DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0042493| response to drug HDAC2;HDAC5;CYP2E1;ABCB1;HDAC1;HDAC4 GO:0043066| negative regulation of apoptotic process ALB;HDAC1;HDAC3;HDAC2 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 29712:[DB06728 DB09030] DB06728|Aniline KLK1;ALB;CYP2E1 DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2J2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2J2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2J2;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 29713:[DB06728 DB04929] DB06728|Aniline KLK1;ALB;CYP2E1 DB04929|DG031 ALOX5AP common genes common pathways 29714:[DB06728 DB04602] DB06728|Aniline KLK1;ALB;CYP2E1 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 29715:[DB06728 DB01561] DB06728|Aniline KLK1;ALB;CYP2E1 DB01561|Androstanedione HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process HSD17B1;CYP2E1 29716:[DB06728 DB08597] DB06728|Aniline KLK1;ALB;CYP2E1 DB08597|6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine ACVR1;FKBP1A common genes common pathways 29717:[DB06728 DB07605] DB06728|Aniline KLK1;ALB;CYP2E1 DB07605|2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 29718:[DB06728 DB08733] DB06728|Aniline KLK1;ALB;CYP2E1 DB08733|(2R,3R)-N^1^-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N^4^-HYDROXY-2-(2-METHYLPROPYL)-3-{[(1,3-THIAZOL-2-YLCARBONYL)AMINO]METHYL}BUTANEDIAMIDE ADAM28 common genes common pathways GO:0006508| proteolysis KLK1;ADAM28 29719:[DB06728 DB03917] DB06728|Aniline KLK1;ALB;CYP2E1 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways GO:0045471| response to ethanol CYP2E1;RBP4 29720:[DB06728 DB05290] DB06728|Aniline KLK1;ALB;CYP2E1 DB05290|SPP 301 EDNRA common genes common pathways 29721:[DB06728 DB09142] DB06728|Aniline KLK1;ALB;CYP2E1 DB09142|Sincalide SLCO1B3 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3 GO:0015721| bile acid and bile salt transport ALB;SLCO1B3 29722:[DB06728 DB06342] DB06728|Aniline KLK1;ALB;CYP2E1 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 29723:[DB06728 DB04299] DB06728|Aniline KLK1;ALB;CYP2E1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways 29724:[DB06728 DB00529] DB06728|Aniline KLK1;ALB;CYP2E1 DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 29725:[DB06728 DB03807] DB06728|Aniline KLK1;ALB;CYP2E1 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways 29726:[DB06728 DB07194] DB06728|Aniline KLK1;ALB;CYP2E1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways 29727:[DB06728 DB09108] DB06728|Aniline KLK1;ALB;CYP2E1 DB09108|Simoctocog Alfa VWF common genes common pathways GO:0002576| platelet degranulation VWF;ALB 29728:[DB06728 DB07423] DB06728|Aniline KLK1;ALB;CYP2E1 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways 29729:[DB06728 DB00537] DB06728|Aniline KLK1;ALB;CYP2E1 DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A5 29730:[DB06728 DB02323] DB06728|Aniline KLK1;ALB;CYP2E1 DB02323|EM-1745 HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process HSD17B1;CYP2E1 29731:[DB06728 DB00713] DB06728|Aniline KLK1;ALB;CYP2E1 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways 29732:[DB06728 DB14055] DB06728|Aniline KLK1;ALB;CYP2E1 DB14055|(S)-Warfarin CYP3A4;CYP2C8;CYP2C9;CYP2C18;CYP2C19 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2C18;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C18;CYP2C9;CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2C9;CYP2C18;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 29733:[DB06728 DB06984] DB06728|Aniline KLK1;ALB;CYP2E1 DB06984|(1R,2R,3R,4S,5R)-4-(BENZYLAMINO)-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL MAN2A1 common genes common pathways 29734:[DB06728 DB00305] DB06728|Aniline KLK1;ALB;CYP2E1 DB00305|Mitomycin POR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;POR GO:0042493| response to drug CYP2E1;POR GO:0055114| oxidation-reduction process CYP2E1;POR GO:0043066| negative regulation of apoptotic process POR;ALB 29735:[DB06728 DB09195] DB06728|Aniline KLK1;ALB;CYP2E1 DB09195|Lorpiprazole HTR2A;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;SLC6A4;CYP2D6;CYP3A4;ALB common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0042493| response to drug HTR2A;CYP2E1;SLC6A4;HTR2C;ADRA1A GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 29736:[DB06728 DB02542] DB06728|Aniline KLK1;ALB;CYP2E1 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways GO:0043066| negative regulation of apoptotic process UBB;ALB GO:0044267| cellular protein metabolic process ALB;UBB 29737:[DB06728 DB01047] DB06728|Aniline KLK1;ALB;CYP2E1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;SMO GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 29738:[DB06728 DB04464] DB06728|Aniline KLK1;ALB;CYP2E1 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0001895| retina homeostasis ALB;B2M GO:0006508| proteolysis CLPP;KLK1 GO:0044267| cellular protein metabolic process SERPINC1;B2M;UBC;ALB GO:0042493| response to drug B2M;MT-ND1;CYP2E1 GO:0043687| post-translational protein modification RABGGTB;SERPINC1;RABGGTA;ALB GO:0055114| oxidation-reduction process CYP2E1;MT-CO1;MT-ND1;MT-CO2 GO:0043066| negative regulation of apoptotic process UBC;ALB 29739:[DB06728 DB00619] DB06728|Aniline KLK1;ALB;CYP2E1 DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6;CYP3A5 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0044267| cellular protein metabolic process ALB;ABCA3 GO:0043066| negative regulation of apoptotic process ALB;PDGFRB;NTRK1;CSF1R GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1;CYP1A2 GO:0002576| platelet degranulation ALB;ORM1 GO:0042493| response to drug CYP2E1;ABCA3;CYP1A2;RET;NTRK1;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1;PTGS1 GO:0043687| post-translational protein modification ALB 29740:[DB06728 DB02796] DB06728|Aniline KLK1;ALB;CYP2E1 DB02796|9-Deazainosine PNP common genes common pathways GO:0042493| response to drug PNP;CYP2E1 29741:[DB06728 DB02162] DB06728|Aniline KLK1;ALB;CYP2E1 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways 29742:[DB06728 DB01263] DB06728|Aniline KLK1;ALB;CYP2E1 DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 29743:[DB06728 DB08374] DB06728|Aniline KLK1;ALB;CYP2E1 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways GO:0006508| proteolysis CTRB1;KLK1 29744:[DB06728 DB04260] DB06728|Aniline KLK1;ALB;CYP2E1 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways GO:0042493| response to drug CYP2E1;PNP 29745:[DB06728 DB08357] DB06728|Aniline KLK1;ALB;CYP2E1 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways 29746:[DB06728 DB00010] DB06728|Aniline KLK1;ALB;CYP2E1 DB00010|Sermorelin GHRHR common genes common pathways 29747:[DB06728 DB08882] DB06728|Aniline KLK1;ALB;CYP2E1 DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006508| proteolysis DPP4;KLK1 29748:[DB06728 DB08362] DB06728|Aniline KLK1;ALB;CYP2E1 DB08362|N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE CSNK2A1 common genes common pathways 29749:[DB06728 DB02049] DB06728|Aniline KLK1;ALB;CYP2E1 DB02049|2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide MMP13 common genes common pathways GO:0006508| proteolysis MMP13;KLK1 GO:0044267| cellular protein metabolic process MMP13;ALB 29750:[DB06728 DB08900] DB06728|Aniline KLK1;ALB;CYP2E1 DB08900|Teduglutide GLP2R common genes common pathways 29751:[DB06728 DB03523] DB06728|Aniline KLK1;ALB;CYP2E1 DB03523|Brequinar DHODH common genes common pathways GO:0042493| response to drug CYP2E1;DHODH GO:0055114| oxidation-reduction process CYP2E1;DHODH 29752:[DB06728 DB13167] DB06728|Aniline KLK1;ALB;CYP2E1 DB13167|Alclofenac PTGS2 common genes common pathways GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 29753:[DB06728 DB05941] DB06728|Aniline KLK1;ALB;CYP2E1 DB05941|Leronlimab CCR5 common genes common pathways 29754:[DB06728 DB00182] DB06728|Aniline KLK1;ALB;CYP2E1 DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0009267| cellular response to starvation CARTPT;ALB GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP2A6 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6 GO:0055114| oxidation-reduction process CYP2E1;CYP2A6;MAOA;CYP2D6;MAOB GO:0042493| response to drug CYP2E1;SLC6A4;SLC6A2;MAOB;SLC6A3;DRD2;ADRA1A GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0045471| response to ethanol MAOB;DRD2;SLC6A3;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 29755:[DB06728 DB13929] DB06728|Aniline KLK1;ALB;CYP2E1 DB13929|Relcovaptan OXTR;AVPR1A common genes common pathways GO:0042493| response to drug OXTR;CYP2E1 29756:[DB06728 DB03589] DB06728|Aniline KLK1;ALB;CYP2E1 DB03589|Alpha-Ketomalonic Acid ME2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ME2 29757:[DB06728 DB00921] DB06728|Aniline KLK1;ALB;CYP2E1 DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;UGT1A1;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP2C19;CYP3A5;UGT1A9;CYP2C9;CYP2C18;CYP3A7;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP2A6;UGT1A1;CYP2C9;CYP3A5;CYP2D6;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6;CYP2D6;CYP2C19;CYP2C8;UGT1A9;UGT1A1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2C18;CYP2E1;CYP2A6 GO:0055114| oxidation-reduction process CYP2C18;CYP3A7;CYP2A6;CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP2C9 GO:0042493| response to drug UGT1A1;ABCB1;ABCG2;CYP2E1 29758:[DB06728 DB02112] DB06728|Aniline KLK1;ALB;CYP2E1 DB02112|Zk-806450 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29759:[DB06728 DB01590] DB06728|Aniline KLK1;ALB;CYP2E1 DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0009267| cellular response to starvation ALB;MTOR GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 29760:[DB06728 DB00036] DB06728|Aniline KLK1;ALB;CYP2E1 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HPN GO:0006508| proteolysis F7;F10;KLK1;HPN 29761:[DB06728 DB03449] DB06728|Aniline KLK1;ALB;CYP2E1 DB03449|N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine NOS2;NOS1 common genes common pathways GO:0055114| oxidation-reduction process NOS2;NOS1;CYP2E1 29762:[DB06728 DB07160] DB06728|Aniline KLK1;ALB;CYP2E1 DB07160|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE CTSB common genes common pathways GO:0006508| proteolysis KLK1;CTSB 29763:[DB06728 DB07567] DB06728|Aniline KLK1;ALB;CYP2E1 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways 29764:[DB06728 DB02991] DB06728|Aniline KLK1;ALB;CYP2E1 DB02991|S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea NOS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS1 29765:[DB06728 DB00661] DB06728|Aniline KLK1;ALB;CYP2E1 DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;ABCC3;SLCO1A2;ABCB11;SLCO1B1 GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2D6;CYP2C19;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP2B6;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP2E1;CYP3A4;ABCC4;CYP2C18 GO:0042493| response to drug ABCC1;ABCG2;ABCC2;ADRA1A;ABCB1;CYP2E1;KCNJ11;CYP1A2;SLC6A4;ABCC4 GO:0002576| platelet degranulation ABCC4;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2E1;CYP1A2;CYP2C18 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C18 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 29766:[DB06728 DB03660] DB06728|Aniline KLK1;ALB;CYP2E1 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 29767:[DB06728 DB01367] DB06728|Aniline KLK1;ALB;CYP2E1 DB01367|Rasagiline MAOB;BCL2;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0045471| response to ethanol MAOB;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process MAOB;CYP2E1;CYP1A2 GO:0042493| response to drug MAOB;CYP2E1;CYP1A2;BCL2 GO:0043066| negative regulation of apoptotic process ALB;BCL2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 29768:[DB06728 DB06916] DB06728|Aniline KLK1;ALB;CYP2E1 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 29769:[DB06728 DB12271] DB06728|Aniline KLK1;ALB;CYP2E1 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways GO:0006508| proteolysis CPN1;CPN2;KLK1 29770:[DB06728 DB02451] DB06728|Aniline KLK1;ALB;CYP2E1 DB02451|B-nonylglucoside RHO;AQP1;CLPS;PNLIP;MIP;KCNJ3 common genes common pathways GO:0042493| response to drug CYP2E1;AQP1 GO:0043066| negative regulation of apoptotic process AQP1;ALB 29771:[DB06728 DB03060] DB06728|Aniline KLK1;ALB;CYP2E1 DB03060|Sri-9662 DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 29772:[DB06728 DB01307] DB06728|Aniline KLK1;ALB;CYP2E1 DB01307|Insulin Detemir INSR;ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 29773:[DB06728 DB02093] DB06728|Aniline KLK1;ALB;CYP2E1 DB02093|5-Phospho-D-Arabinohydroxamic Acid GPI common genes common pathways 29774:[DB06728 DB01571] DB06728|Aniline KLK1;ALB;CYP2E1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;CYP2E1 29775:[DB06728 DB03367] DB06728|Aniline KLK1;ALB;CYP2E1 DB03367|PF-00356231 MMP12 common genes common pathways GO:0006508| proteolysis KLK1;MMP12 29776:[DB06728 DB00336] DB06728|Aniline KLK1;ALB;CYP2E1 DB00336|Nitrofural gor;mdh;XDH common genes common pathways GO:0055114| oxidation-reduction process XDH;CYP2E1 29777:[DB06728 DB02143] DB06728|Aniline KLK1;ALB;CYP2E1 DB02143|N-Isopropyl-N'-Hydroxyguanidine NOS1 common genes common pathways GO:0055114| oxidation-reduction process NOS1;CYP2E1 29778:[DB06728 DB00353] DB06728|Aniline KLK1;ALB;CYP2E1 DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;DRD1;HTR2B GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB 29779:[DB06728 DB01408] DB06728|Aniline KLK1;ALB;CYP2E1 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0042493| response to drug CYP2E1;BCHE 29780:[DB06728 DB00652] DB06728|Aniline KLK1;ALB;CYP2E1 DB00652|Pentazocine OPRM1;OPRK1;SIGMAR1 common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 29781:[DB06728 DB02689] DB06728|Aniline KLK1;ALB;CYP2E1 DB02689|S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine ARG1 common genes common pathways GO:0042493| response to drug CYP2E1;ARG1 29782:[DB06728 DB00340] DB06728|Aniline KLK1;ALB;CYP2E1 DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways 29783:[DB06728 DB08737] DB06728|Aniline KLK1;ALB;CYP2E1 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways 29784:[DB06728 DB07390] DB06728|Aniline KLK1;ALB;CYP2E1 DB07390|2-[3-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YL)-UREIDO]-N-METHYL-3-PHENYL-PROPIONAMIDE MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 29785:[DB06728 DB04343] DB06728|Aniline KLK1;ALB;CYP2E1 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways 29786:[DB06728 DB08820] DB06728|Aniline KLK1;ALB;CYP2E1 DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ORM1;ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 29787:[DB06728 DB04478] DB06728|Aniline KLK1;ALB;CYP2E1 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;SORD GO:0042493| response to drug SORD;CYP2E1 29788:[DB06728 DB00324] DB06728|Aniline KLK1;ALB;CYP2E1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 29789:[DB06728 DB01955] DB06728|Aniline KLK1;ALB;CYP2E1 DB01955|1,4-Butanediol MAN1B1;PLA2G2A;PLA2G2E common genes common pathways 29790:[DB06728 DB07380] DB06728|Aniline KLK1;ALB;CYP2E1 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways GO:0006508| proteolysis CTRB1;KLK1 29791:[DB06728 DB02067] DB06728|Aniline KLK1;ALB;CYP2E1 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways 29792:[DB06728 DB02429] DB06728|Aniline KLK1;ALB;CYP2E1 DB02429|4-(Aminosulfonyl)-N-[(4-Fluorophenyl)Methyl]-Benzamide CA2 common genes common pathways 29793:[DB06728 DB03341] DB06728|Aniline KLK1;ALB;CYP2E1 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways 29794:[DB06728 DB04938] DB06728|Aniline KLK1;ALB;CYP2E1 DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2B6;CYP2C9 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2B6;CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9;CYP2B6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 29795:[DB06728 DB02477] DB06728|Aniline KLK1;ALB;CYP2E1 DB02477|[Cyclohexylethyl]-[[[[4-[2-Methyl-1-Imidazolyl-Butyl]Phenyl]Acetyl]-Seryl]-Lysinyl]-Amine NMT1 common genes common pathways 29796:[DB06728 DB05072] DB06728|Aniline KLK1;ALB;CYP2E1 DB05072|AV608 TACR1 common genes common pathways GO:0045471| response to ethanol TACR1;CYP2E1 GO:0010193| response to ozone TACR1;CYP2E1 29797:[DB06728 DB13878] DB06728|Aniline KLK1;ALB;CYP2E1 DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;UGT1A1;CYP3A5 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCG2;ABCB1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP2E1;CYP3A4;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP2E1;CYP3A4 29798:[DB06728 DB02648] DB06728|Aniline KLK1;ALB;CYP2E1 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways 29799:[DB06728 DB06406] DB06728|Aniline KLK1;ALB;CYP2E1 DB06406|Idraparinux F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 29800:[DB06728 DB02583] DB06728|Aniline KLK1;ALB;CYP2E1 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 29801:[DB06728 DB01727] DB06728|Aniline KLK1;ALB;CYP2E1 DB01727|Isocitric Acid icd;icd;ACO2;IDH2;IDH1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;IDH1;IDH2 29802:[DB06728 DB04629] DB06728|Aniline KLK1;ALB;CYP2E1 DB04629|Aplyronine A ACTA1 common genes common pathways 29803:[DB06728 DB04230] DB06728|Aniline KLK1;ALB;CYP2E1 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 29804:[DB06728 DB02078] DB06728|Aniline KLK1;ALB;CYP2E1 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways GO:0042493| response to drug FYN;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PPIF GO:0045471| response to ethanol CYP2E1;FYN 29805:[DB06728 DB13961] DB06728|Aniline KLK1;ALB;CYP2E1 DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process NFKB1;PTGS2;FFAR4;PPARD;ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;PTGS2 GO:0042493| response to drug SREBF1;PPARG;CYP2E1;PTGS2 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| PTGS2;ALB GO:0009267| cellular response to starvation ALB;SREBF1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;SREBF1 29806:[DB06728 DB00261] DB06728|Aniline KLK1;ALB;CYP2E1 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0042493| response to drug PDE3A;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 29807:[DB06728 DB00444] DB06728|Aniline KLK1;ALB;CYP2E1 DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP3A5;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C19;CYP3A5;CYP2C9 GO:0042493| response to drug CYP2E1;ABCG2;ABCC6 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1 29808:[DB06728 DB01942] DB06728|Aniline KLK1;ALB;CYP2E1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process NOS1;GPHN;CYP2E1;HMOX1;CTBP1 29809:[DB06728 DB07796] DB06728|Aniline KLK1;ALB;CYP2E1 DB07796|(3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 29810:[DB06728 DB01098] DB06728|Aniline KLK1;ALB;CYP2E1 DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19;CYP3A5 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;HMGCR GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C19 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0042493| response to drug ABCC2;ABCG2;ABCC1;ABCC4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;HMGCR;ABCC4;CYP2C9;CYP3A5;CYP2C19 GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process HMGCR;CYP2E1;CYP3A4;CYP3A5;CYP2C19;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1A2;SLCO1B1;SLC22A8;SLCO1B3 GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1A2;ABCB11;SLCO1B1;SLCO1B3 GO:0044267| cellular protein metabolic process ALB 29811:[DB06728 DB08447] DB06728|Aniline KLK1;ALB;CYP2E1 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways 29812:[DB06728 DB08258] DB06728|Aniline KLK1;ALB;CYP2E1 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;EPHX2 GO:0017144| drug metabolic process EPHX2;CYP2E1 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2E1 29813:[DB06728 DB13508] DB06728|Aniline KLK1;ALB;CYP2E1 DB13508|Cloranolol CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 29814:[DB06728 DB03056] DB06728|Aniline KLK1;ALB;CYP2E1 DB03056|4-Piperidino-Piperidine CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP2E1 29815:[DB06728 DB01007] DB06728|Aniline KLK1;ALB;CYP2E1 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4;CYP51A1 GO:0010243| response to organic nitrogen CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0018910| benzene metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP51A1;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 29816:[DB06728 DB06711] DB06728|Aniline KLK1;ALB;CYP2E1 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 29817:[DB06728 DB00513] DB06728|Aniline KLK1;ALB;CYP2E1 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways GO:0044267| cellular protein metabolic process PLG;ALB GO:0017144| drug metabolic process AOX1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;AOX1 GO:0002576| platelet degranulation ALB;PLG GO:0006508| proteolysis PLG;PLAT;LPA;KLK1 29818:[DB06728 DB03964] DB06728|Aniline KLK1;ALB;CYP2E1 DB03964|4-Hydroxy-Aconitate Ion ACO2 common genes common pathways 29819:[DB06728 DB09481] DB06728|Aniline KLK1;ALB;CYP2E1 DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0042493| response to drug CYP2E1;GRIN2A GO:0045471| response to ethanol GRIN3A;GRIN2A;GRIN1;CYP2E1;GRIN2B 29820:[DB06728 DB07666] DB06728|Aniline KLK1;ALB;CYP2E1 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 29821:[DB06728 DB04237] DB06728|Aniline KLK1;ALB;CYP2E1 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways 29822:[DB06728 DB03115] DB06728|Aniline KLK1;ALB;CYP2E1 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways 29823:[DB06728 DB03924] DB06728|Aniline KLK1;ALB;CYP2E1 DB03924|5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone CSNK2A1 common genes common pathways 29824:[DB06728 DB02489] DB06728|Aniline KLK1;ALB;CYP2E1 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 29825:[DB06728 DB13954] DB06728|Aniline KLK1;ALB;CYP2E1 DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes ALB common pathways GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19;CYP1A1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP3A5;CYP2C8;CYP2C19;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP1A1;CYP2C9;CYP2C8;CYP2C19;CYP1B1 GO:0043066| negative regulation of apoptotic process ALB;BECN1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A7;CYP1A2;HSD17B2;CYP3A4;CYP2E1;CYP1B1;CYP3A5;CYP2C19;CYP2C8;CYP1A1;CYP2C9 GO:0042493| response to drug CYP1A1;BECN1;UGT1A1;ABCG2;ABCB1;CYP2E1;CYP1A2 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1C1;SLC22A11;SLCO4A1;SLCO1A2;SLC22A8;SLCO1B1;SLCO1B3 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;NR1I2;CYP2C9;CYP1A1;UGT1A1;CYP2C19;CYP2C8;CYP3A5;CYP1B1 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2C9;CYP1A1;UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;SLCO1B3;NCOA2;SLCO1C1;ALB;SLCO2B1 29826:[DB06728 DB13746] DB06728|Aniline KLK1;ALB;CYP2E1 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP2C9 29827:[DB06728 DB03061] DB06728|Aniline KLK1;ALB;CYP2E1 DB03061|(R)-N-(1-Methyl-Hexyl)-Formamide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1C 29828:[DB06728 DB01410] DB06728|Aniline KLK1;ALB;CYP2E1 DB01410|Ciclesonide NR3C1;CYP3A4;CYP2D6;CES1;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CES1;CYP2D6 29829:[DB06728 DB03802] DB06728|Aniline KLK1;ALB;CYP2E1 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways 29830:[DB06728 DB04365] DB06728|Aniline KLK1;ALB;CYP2E1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways 29831:[DB06728 DB01593] DB06728|Aniline KLK1;ALB;CYP2E1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0044267| cellular protein metabolic process APCS;TF;APOL1;ITIH2;P4HB;GSN;APLP2;C3;SERPIND1;CP;SERPINA1;TTR;INS;APOA2;APP;APOE;APOA4;SEMG1;FN1;FGA;F2;KNG1;AHSG;ALB;APOA1;IGFALS GO:0008202| steroid metabolic process APOA1;APOBR;APOE;APOL1;CYP2E1 GO:0098869| S100A9;ALB;HBB;HBA1;APOE GO:0055114| oxidation-reduction process PRDX1;PDIA3;GAPDHS;CCS;CP;ADH1C;P4HB;SOD1;CYP2E1 GO:0043687| post-translational protein modification FN1;APOE;APP;APOA2;APOA1;ALB;AHSG;KNG1;FGA;C3;APLP2;P4HB;APOL1;ITIH2;TF;SERPINA1;CP;SERPIND1 GO:0042493| response to drug TP73;APOA1;TP53;MDM2;APOA2;HDAC1;HDAC4;NME1;SOD1;CYP2E1;MGMT GO:0010243| response to organic nitrogen TP73;TP53;CYP2E1 GO:0002576| platelet degranulation SERPINA1;A2M;TF;APLP2;SOD1;ITIH4;FGA;KNG1;SERPINA3;A1BG;AHSG;APOA1;ALB;ITIH3;APP;ALDOA;SERPINA4;CLU;ORM2;FN1 GO:0043066| negative regulation of apoptotic process SOD1;MGMT;MT3;HDAC1;MMP9;TP53;MDM2;ALB GO:0001895| retina homeostasis PRDX1;ALB;JCHAIN;TF;IGHA1;SOD1;KRT1 GO:0034375| high-density lipoprotein particle remodeling APOA2;APOA4;APOE;APOA1;ALB GO:0006641| triglyceride metabolic process CYP2E1;APOBR;APOE;APOA2 GO:0006898| receptor-mediated endocytosis APOL1;IGLV3-21;VTN;IGHA1;CFI;IGKV1-17;ALB;APOA1;JCHAIN;APOBR;APOE;HPR;HBB;HBA1 GO:0006508| proteolysis F12;CPE;IGLV3-21;BRCC3;C1QC;KLKB1;C3;CFI;C1S;DCD;KLK1;C4B;C1QB;PDIA3;C1R;MMP9;IDE;CPN1;F2;PDCD6;FCN3;CPN2;CFB;IGKV1-17 GO:0045471| response to ethanol CYP2E1;MGMT;SOD1;S100A8;GSN;TUFM;TP53 29832:[DB06728 DB00075] DB06728|Aniline KLK1;ALB;CYP2E1 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0006508| proteolysis C1QB;C1R;KLK1;C1QA;C1S;C1QC 29833:[DB06728 DB09063] DB06728|Aniline KLK1;ALB;CYP2E1 DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9 GO:0042493| response to drug ABCB1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 29834:[DB06728 DB13893] DB06728|Aniline KLK1;ALB;CYP2E1 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways GO:0006898| receptor-mediated endocytosis ENPP1;ALB 29835:[DB06728 DB04194] DB06728|Aniline KLK1;ALB;CYP2E1 DB04194|Chitotriose LYZ common genes common pathways GO:0044267| cellular protein metabolic process ALB;LYZ GO:0001895| retina homeostasis ALB;LYZ 29836:[DB06728 DB02057] DB06728|Aniline KLK1;ALB;CYP2E1 DB02057|(S)-AMPA GRIA2 common genes common pathways 29837:[DB06728 DB08387] DB06728|Aniline KLK1;ALB;CYP2E1 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 29838:[DB06728 DB00607] DB06728|Aniline KLK1;ALB;CYP2E1 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes ALB common pathways GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 29839:[DB06728 DB05932] DB06728|Aniline KLK1;ALB;CYP2E1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;FLT4;VEGFA GO:0002576| platelet degranulation ALB;VEGFA 29840:[DB06728 DB06786] DB06728|Aniline KLK1;ALB;CYP2E1 DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process SMO;ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 29841:[DB06728 DB00514] DB06728|Aniline KLK1;ALB;CYP2E1 DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes CYP2E1 common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A7;CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2C9;CYP3A4;CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2B6;CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP2C8;CYP2C19;NCF2;CYP2C9;CYBB;CYP2B6;CYBA;CYP3A7;CYP3A4;CYP2E1;NCF1;NCF4 GO:0042493| response to drug SLC6A4;CYBA;CYP2E1;SLC6A2;CYBB GO:0010243| response to organic nitrogen CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0045471| response to ethanol OPRK1;GRIN3A;CHRNB2;CYP2E1;OPRM1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP3A5;CYP2C8;CYP2C19;CYP2D6 29842:[DB06728 DB01101] DB06728|Aniline KLK1;ALB;CYP2E1 DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways GO:0045471| response to ethanol CYP2E1;TYMS GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;DPYD;CYP2E1 GO:0042493| response to drug TYMS;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 29843:[DB06728 DB07513] DB06728|Aniline KLK1;ALB;CYP2E1 DB07513|7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE MAOB common genes common pathways GO:0042493| response to drug MAOB;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;MAOB GO:0045471| response to ethanol CYP2E1;MAOB 29844:[DB06728 DB13141] DB06728|Aniline KLK1;ALB;CYP2E1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A43;CYP3A4;CYP2E1;CYP3A7 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 29845:[DB06728 DB13867] DB06728|Aniline KLK1;ALB;CYP2E1 DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 29846:[DB06728 DB07284] DB06728|Aniline KLK1;ALB;CYP2E1 DB07284|N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE BACE1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;BACE1 GO:0006508| proteolysis BACE1;KLK1 29847:[DB06728 DB05096] DB06728|Aniline KLK1;ALB;CYP2E1 DB05096|LY2140023 GRM2;GRM3 common genes common pathways 29848:[DB06728 DB01275] DB06728|Aniline KLK1;ALB;CYP2E1 DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process AOC3;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process P4HA1;AOC3;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 29849:[DB06728 DB12092] DB06728|Aniline KLK1;ALB;CYP2E1 DB12092|Naftopidil CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 29850:[DB06728 DB05343] DB06728|Aniline KLK1;ALB;CYP2E1 DB05343|Arundic acid S100B common genes common pathways 29851:[DB06728 DB00134] DB06728|Aniline KLK1;ALB;CYP2E1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0006508| proteolysis METAP2;KLK1 GO:0009267| cellular response to starvation MARS;GLUL;ALB GO:0042493| response to drug CYP2E1;MTHFR GO:0055114| oxidation-reduction process MSRB1;MSRB2;MTRR;MSRA;MTHFR;CYP2E1 29852:[DB06728 DB04973] DB06728|Aniline KLK1;ALB;CYP2E1 DB04973|LErafAON RAF1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RAF1 29853:[DB06728 DB05895] DB06728|Aniline KLK1;ALB;CYP2E1 DB05895|HGS-TR2J TNFRSF10B common genes common pathways 29854:[DB06728 DB02943] DB06728|Aniline KLK1;ALB;CYP2E1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways GO:0098869| ALB;GSTA1 29855:[DB06728 DB01327] DB06728|Aniline KLK1;ALB;CYP2E1 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes ALB common pathways GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;ABCC4 GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLC22A11 GO:0045471| response to ethanol IL2;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB 29856:[DB06728 DB07280] DB06728|Aniline KLK1;ALB;CYP2E1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 29857:[DB06728 DB03182] DB06728|Aniline KLK1;ALB;CYP2E1 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 29858:[DB06728 DB00342] DB06728|Aniline KLK1;ALB;CYP2E1 DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2J2;CYP2E1;CYP3A7;CYP3A5;CYP2D6;CYP2C8 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP3A5;CYP3A7;CYP2J2;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2J2;CYP2E1;CYP2C8 29859:[DB06728 DB02021] DB06728|Aniline KLK1;ALB;CYP2E1 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;AKR1B10;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0008202| steroid metabolic process AKR1B10;CYP2E1 29860:[DB06728 DB02164] DB06728|Aniline KLK1;ALB;CYP2E1 DB02164|N-Sulfo-Flavin Mononucleotide HAO1 common genes common pathways GO:0055114| oxidation-reduction process HAO1;CYP2E1 29861:[DB06728 DB04616] DB06728|Aniline KLK1;ALB;CYP2E1 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways 29862:[DB06728 DB00398] DB06728|Aniline KLK1;ALB;CYP2E1 DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP2B6;CYP2C9;UGT1A9 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0010243| response to organic nitrogen CYP2E1;FLT3;ABCC4 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4;ABCC4 GO:0042493| response to drug ABCC4;RET;CYP1A2;CYP2E1;ABCB1;ABCC2;ABCG2;UGT1A1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2B6;CYP2C9;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process PDGFRB;FLT4;ALB;BRAF;KDR;RAF1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2C9;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP2B6;CYP2C9;UGT1A1 29863:[DB06728 DB03879] DB06728|Aniline KLK1;ALB;CYP2E1 DB03879|alpha-L-methyl-fucose MBL2 common genes common pathways GO:0006508| proteolysis KLK1;MBL2 29864:[DB06728 DB02220] DB06728|Aniline KLK1;ALB;CYP2E1 DB02220|AL7089A CA2 common genes common pathways 29865:[DB06728 DB13923] DB06728|Aniline KLK1;ALB;CYP2E1 DB13923|Emicizumab F9;F10 common genes common pathways GO:0006508| proteolysis KLK1;F10;F9 29866:[DB06728 DB07128] DB06728|Aniline KLK1;ALB;CYP2E1 DB07128|N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINE F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis KLK1;F2 29867:[DB06728 DB01220] DB06728|Aniline KLK1;ALB;CYP2E1 DB01220|Rifaximin rpoB;NR1I2;CYP3A4;CYP2C19;CYP2C8;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;NR1I2;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process NR1I2;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6 29868:[DB06728 DB14061] DB06728|Aniline KLK1;ALB;CYP2E1 DB14061|Hycanthone ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 29869:[DB06728 DB00112] DB06728|Aniline KLK1;ALB;CYP2E1 DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0002576| platelet degranulation ALB;VEGFA GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB GO:0006508| proteolysis C1R;C1QB;C1QA;KLK1;C1QC 29870:[DB06728 DB09034] DB06728|Aniline KLK1;ALB;CYP2E1 DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 29871:[DB06728 DB05771] DB06728|Aniline KLK1;ALB;CYP2E1 DB05771|LLL-3348 IL10 common genes common pathways GO:0043066| negative regulation of apoptotic process IL10;ALB GO:0042493| response to drug IL10;CYP2E1 29872:[DB06728 DB07470] DB06728|Aniline KLK1;ALB;CYP2E1 DB07470|(3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 29873:[DB06728 DB01242] DB06728|Aniline KLK1;ALB;CYP2E1 DB01242|Clomipramine SLC6A4;HTR2A;HTR2B;HTR2C;SLC6A2;GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;ALB;ABCB1 common genes ALB common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0042493| response to drug CYP1A2;CYP2E1;HTR2A;SLC6A4;SLC6A2;ABCB1;HTR2B;HTR2C GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB;HTR2B;GSTP1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1A2;CYP2E1 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| GSTP1;ALB GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB 29874:[DB06728 DB06458] DB06728|Aniline KLK1;ALB;CYP2E1 DB06458|Remacemide CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 29875:[DB06728 DB12831] DB06728|Aniline KLK1;ALB;CYP2E1 DB12831|Gabexate KLKB1;F2;PLG;PRSS1;C1S;C1R common genes common pathways GO:0044267| cellular protein metabolic process PLG;ALB;F2 GO:0002576| platelet degranulation PLG;ALB GO:0006508| proteolysis F2;PLG;PRSS1;C1R;KLK1;C1S;KLKB1 29876:[DB06728 DB00001] DB06728|Aniline KLK1;ALB;CYP2E1 DB00001|Lepirudin F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 29877:[DB06728 DB07333] DB06728|Aniline KLK1;ALB;CYP2E1 DB07333|N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB 29878:[DB06728 DB07840] DB06728|Aniline KLK1;ALB;CYP2E1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways 29879:[DB06728 DB05235] DB06728|Aniline KLK1;ALB;CYP2E1 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0055114| oxidation-reduction process CRYM;CYP2E1 GO:0044267| cellular protein metabolic process ALB;TTR 29880:[DB06728 DB00470] DB06728|Aniline KLK1;ALB;CYP2E1 DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP1A1;CYP2C9;CYP2C19 GO:0042493| response to drug CYP1A1;ABCG2;ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2A6;PTGS1;CYP1A1;CYP2C9;CYP2C19 GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4;CYP1A1;CYP2C9;CYP2C19 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2A6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4;PTGS1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2E1;CYP3A4 GO:0045471| response to ethanol CNR1;CYP2E1 29881:[DB06728 DB01295] DB06728|Aniline KLK1;ALB;CYP2E1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0042493| response to drug ADRA1A;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 29882:[DB06728 DB08164] DB06728|Aniline KLK1;ALB;CYP2E1 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 29883:[DB06728 DB01336] DB06728|Aniline KLK1;ALB;CYP2E1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways 29884:[DB06728 DB06655] DB06728|Aniline KLK1;ALB;CYP2E1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways GO:0006508| proteolysis KLK1;MME;DPP4 29885:[DB06728 DB05268] DB06728|Aniline KLK1;ALB;CYP2E1 DB05268|iCo-007 RAF1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RAF1 29886:[DB06728 DB04539] DB06728|Aniline KLK1;ALB;CYP2E1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes ALB common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 29887:[DB06728 DB04312] DB06728|Aniline KLK1;ALB;CYP2E1 DB04312|2,3-Difluorobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;CYP2E1 29888:[DB06728 DB00559] DB06728|Aniline KLK1;ALB;CYP2E1 DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process EDNRB;ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1;CYP3A4 29889:[DB06728 DB04254] DB06728|Aniline KLK1;ALB;CYP2E1 DB04254|8-Benzo[1,3]Dioxol-,5-Ylmethyl-9-Butyl-2-Fluoro-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 29890:[DB06728 DB00162] DB06728|Aniline KLK1;ALB;CYP2E1 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes ALB common pathways GO:0042493| response to drug APOD;CYP2E1;CYP1A1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process DHRS3;RETSAT;ALDH1A1;RDH11;RDH13;RDH14;CYP26A1;CYP2E1;RDH8;RDH5;ALDH1A2;DHRS4;RDH12;ALDH1A3;CYP1A1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP1A1;DHRS4;CYP2E1 GO:0006508| proteolysis KLK1;RBP3 GO:0006805| xenobiotic metabolic process CYP26A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol RBP4;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 29891:[DB06728 DB00823] DB06728|Aniline KLK1;ALB;CYP2E1 DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 29892:[DB06728 DB05372] DB06728|Aniline KLK1;ALB;CYP2E1 DB05372|CP-945598 CNR1 common genes common pathways GO:0045471| response to ethanol CNR1;CYP2E1 29893:[DB06728 DB02643] DB06728|Aniline KLK1;ALB;CYP2E1 DB02643|N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate IGF1;MAOB common genes common pathways GO:0045471| response to ethanol CYP2E1;MAOB GO:0044267| cellular protein metabolic process IGF1;ALB GO:0002576| platelet degranulation IGF1;ALB GO:0043066| negative regulation of apoptotic process ALB;IGF1 GO:0042493| response to drug CYP2E1;MAOB GO:0055114| oxidation-reduction process MAOB;CYP2E1 29894:[DB06728 DB07908] DB06728|Aniline KLK1;ALB;CYP2E1 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways 29895:[DB06728 DB06586] DB06728|Aniline KLK1;ALB;CYP2E1 DB06586|Cetilistat PNLIP common genes common pathways 29896:[DB06728 DB02684] DB06728|Aniline KLK1;ALB;CYP2E1 DB02684|5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 29897:[DB06728 DB00174] DB06728|Aniline KLK1;ALB;CYP2E1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0006508| proteolysis KLK1;ASRGL1 GO:0043066| negative regulation of apoptotic process ASNS;ALB 29898:[DB06728 DB06942] DB06728|Aniline KLK1;ALB;CYP2E1 DB06942|N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 29899:[DB06728 DB04873] DB06728|Aniline KLK1;ALB;CYP2E1 DB04873|Piboserod HTR4 common genes common pathways 29900:[DB06728 DB01154] DB06728|Aniline KLK1;ALB;CYP2E1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes CYP2E1 common pathways GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2E1 GO:0042493| response to drug KCNJ11;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0010193| response to ozone CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 29901:[DB06728 DB07046] DB06728|Aniline KLK1;ALB;CYP2E1 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways 29902:[DB06728 DB02999] DB06728|Aniline KLK1;ALB;CYP2E1 DB02999|Quisqualate GRIA2;GRIK2 common genes common pathways 29903:[DB06728 DB01356] DB06728|Aniline KLK1;ALB;CYP2E1 DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:0043066| negative regulation of apoptotic process GSK3B;ALB 29904:[DB06728 DB02983] DB06728|Aniline KLK1;ALB;CYP2E1 DB02983|Para-Mercury-Benzenesulfonic Acid CLC;ESR2 common genes common pathways 29905:[DB06728 DB11345] DB06728|Aniline KLK1;ALB;CYP2E1 DB11345|(S)-camphor TRPV1;TRPV3;TRPA1;TRPM8 common genes common pathways GO:0010243| response to organic nitrogen TRPV1;CYP2E1 GO:0042493| response to drug TRPA1;CYP2E1 29906:[DB06728 DB01031] DB06728|Aniline KLK1;ALB;CYP2E1 DB01031|Ethinamate CA1;CA2 common genes common pathways 29907:[DB06728 DB06779] DB06728|Aniline KLK1;ALB;CYP2E1 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0043687| post-translational protein modification SERPINC1;ALB GO:0002576| platelet degranulation VEGFA;SELP;ALB GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0044267| cellular protein metabolic process SERPINC1;ALB 29908:[DB06728 DB11937] DB06728|Aniline KLK1;ALB;CYP2E1 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;AHR 29909:[DB06728 DB06159] DB06728|Aniline KLK1;ALB;CYP2E1 DB06159|Rubitecan TOP1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 29910:[DB06728 DB05501] DB06728|Aniline KLK1;ALB;CYP2E1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways 29911:[DB06728 DB07771] DB06728|Aniline KLK1;ALB;CYP2E1 DB07771|[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID KRAS;FNTA;FNTB common genes common pathways 29912:[DB06728 DB03839] DB06728|Aniline KLK1;ALB;CYP2E1 DB03839|D-Tyrosine SLC16A10 common genes common pathways 29913:[DB06728 DB06702] DB06728|Aniline KLK1;ALB;CYP2E1 DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 29914:[DB06728 DB02400] DB06728|Aniline KLK1;ALB;CYP2E1 DB02400|5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NQO1 GO:0043066| negative regulation of apoptotic process ALB;NQO1 GO:0006805| xenobiotic metabolic process CYP2E1;NQO1 GO:0045471| response to ethanol NQO1;CYP2E1 29915:[DB06728 DB06862] DB06728|Aniline KLK1;ALB;CYP2E1 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways GO:0006508| proteolysis KLK1;CASP3 GO:0042493| response to drug CYP2E1;CASP3 GO:0043066| negative regulation of apoptotic process ALB;CASP3 29916:[DB06728 DB06492] DB06728|Aniline KLK1;ALB;CYP2E1 DB06492|Mirococept C3 common genes common pathways GO:0006508| proteolysis C3;KLK1 GO:0044267| cellular protein metabolic process C3;ALB GO:0043687| post-translational protein modification C3;ALB 29917:[DB06728 DB04125] DB06728|Aniline KLK1;ALB;CYP2E1 DB04125|N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)-4-Acetyl-Piperazine PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 29918:[DB06728 DB01426] DB06728|Aniline KLK1;ALB;CYP2E1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0002576| platelet degranulation ALB;ORM1 29919:[DB06728 DB04551] DB06728|Aniline KLK1;ALB;CYP2E1 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO2A1 29920:[DB06728 DB12520] DB06728|Aniline KLK1;ALB;CYP2E1 DB12520|Plozalizumab CCR2 common genes common pathways 29921:[DB06728 DB07658] DB06728|Aniline KLK1;ALB;CYP2E1 DB07658|AC-(D)PHE-PRO-BOROLYS-OH F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 29922:[DB06728 DB07558] DB06728|Aniline KLK1;ALB;CYP2E1 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways GO:0043687| post-translational protein modification PSMA7;ALB GO:0006508| proteolysis KLK1;PSMA7 29923:[DB06728 DB05037] DB06728|Aniline KLK1;ALB;CYP2E1 DB05037|AT7519 CDK1;CDK2 common genes common pathways GO:0042493| response to drug CDK1;CYP2E1 GO:0010243| response to organic nitrogen CDK1;CYP2E1 GO:0043066| negative regulation of apoptotic process CDK1;ALB GO:0045471| response to ethanol CDK1;CYP2E1 29924:[DB06728 DB08830] DB06728|Aniline KLK1;ALB;CYP2E1 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways 29925:[DB06728 DB07958] DB06728|Aniline KLK1;ALB;CYP2E1 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways 29926:[DB06728 DB00462] DB06728|Aniline KLK1;ALB;CYP2E1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways 29927:[DB06728 DB04850] DB06728|Aniline KLK1;ALB;CYP2E1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB 29928:[DB06728 DB05142] DB06728|Aniline KLK1;ALB;CYP2E1 DB05142|ND7001 PDE2A;PDE2A common genes common pathways 29929:[DB06728 DB08949] DB06728|Aniline KLK1;ALB;CYP2E1 DB08949|Inositol nicotinate HCAR3;HCAR2;ATP5B;DGAT2;SLC5A8 common genes common pathways 29930:[DB06728 DB06266] DB06728|Aniline KLK1;ALB;CYP2E1 DB06266|Lonidamine CFTR;HK1 common genes common pathways 29931:[DB06728 DB00351] DB06728|Aniline KLK1;ALB;CYP2E1 DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 29932:[DB06728 DB04724] DB06728|Aniline KLK1;ALB;CYP2E1 DB04724|(S)-2-((S)-3-ISOBUTYL-2,5-DIOXO-4-QUINOLIN-3-YLMETHYL-[1,4]DIAZEPAN-1YL)-N-METHYL-3-NAPHTALEN-2-YL-PROPIONAMIDE ITGAL common genes common pathways 29933:[DB06728 DB04858] DB06728|Aniline KLK1;ALB;CYP2E1 DB04858|Tirapazamine CYP2E1 common genes CYP2E1 common pathways GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2E1 GO:0017144| drug metabolic process CYP2E1 GO:0008202| steroid metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 29934:[DB06728 DB03348] DB06728|Aniline KLK1;ALB;CYP2E1 DB03348|Huperzine B ACHE common genes common pathways 29935:[DB06728 DB05930] DB06728|Aniline KLK1;ALB;CYP2E1 DB05930|SB-559448 MPL common genes common pathways 29936:[DB06728 DB02742] DB06728|Aniline KLK1;ALB;CYP2E1 DB02742|Kifunensine MAN2A1;MAN1B1 common genes common pathways 29937:[DB06728 DB01864] DB06728|Aniline KLK1;ALB;CYP2E1 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways GO:0043687| post-translational protein modification ALB;RAB11A 29938:[DB06728 DB11672] DB06728|Aniline KLK1;ALB;CYP2E1 DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6;CYP2C9;CYP2D6 GO:0098869| ALB;GSTP1;GSTA1 GO:0017144| drug metabolic process CBR1;CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C9;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2B6 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0042493| response to drug PPARG;ABCB1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CBR1;CYP2E1;CYP3A4;CYP1A2;CYP2D6;CYP2C9;CYP2B6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;GSTP1;CYP2D6;CYP2C9;CYP2B6 29939:[DB06728 DB07528] DB06728|Aniline KLK1;ALB;CYP2E1 DB07528|3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB 29940:[DB06728 DB02071] DB06728|Aniline KLK1;ALB;CYP2E1 DB02071|WAY-151693 MMP13 common genes common pathways GO:0044267| cellular protein metabolic process MMP13;ALB GO:0006508| proteolysis MMP13;KLK1 29941:[DB06728 DB05457] DB06728|Aniline KLK1;ALB;CYP2E1 DB05457|OSI-7904L TYMS common genes common pathways GO:0042493| response to drug CYP2E1;TYMS GO:0045471| response to ethanol CYP2E1;TYMS 29942:[DB06728 DB02032] DB06728|Aniline KLK1;ALB;CYP2E1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways GO:0006508| proteolysis ACE;KLK1 29943:[DB06728 DB00668] DB06728|Aniline KLK1;ALB;CYP2E1 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0042493| response to drug CYP2E1;COMT;MAOB;ADRA1A GO:0055114| oxidation-reduction process CYP2C9;MAOB;CYP3A4;CYP2E1;MAOA GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;MAOB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0006898| receptor-mediated endocytosis ADRB2;ALB 29944:[DB06728 DB04489] DB06728|Aniline KLK1;ALB;CYP2E1 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways GO:0006508| proteolysis CPD;KLK1 29945:[DB06728 DB11081] DB06728|Aniline KLK1;ALB;CYP2E1 DB11081|Aluminum chloride GLUD1 common genes common pathways GO:0055114| oxidation-reduction process GLUD1;CYP2E1 29946:[DB06728 DB09295] DB06728|Aniline KLK1;ALB;CYP2E1 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 29947:[DB06728 DB00328] DB06728|Aniline KLK1;ALB;CYP2E1 DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes ALB common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2C19;AKR1C3;CYP2E1;UGT2B7 GO:0009267| cellular response to starvation ALB;AKR1C3 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A7;SLC22A11;SLCO1A2;SLC22A8;SLCO1B1 GO:0098869| PTGS1;PTGS2;ALB GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2C9;CYP2C19;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;ABCB11;SLC10A1;ALB;ABCC3 GO:0043066| negative regulation of apoptotic process GLO1;PTGS2;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0002576| platelet degranulation ALB;ABCC4 GO:0042493| response to drug PPARG;ABCC1;ABCC6;UGT1A1;ABCC2;ABCB1;CYP2E1;PTGS2;ABCC4 GO:0055114| oxidation-reduction process PTGR2;ABCC4;PTGS1;CYP2E1;AKR1C3;PTGS2;CYP2C19;CYP2C9 GO:0043687| post-translational protein modification ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1;ABCC4 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP2C19 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;PTGS1;CYP2C9;UGT1A9;CYP2C19 29948:[DB06728 DB06011] DB06728|Aniline KLK1;ALB;CYP2E1 DB06011|AMG-222 DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 29949:[DB06728 DB07711] DB06728|Aniline KLK1;ALB;CYP2E1 DB07711|(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ADA;ALB GO:0042493| response to drug ADA;CYP2E1 29950:[DB06728 DB00394] DB06728|Aniline KLK1;ALB;CYP2E1 DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 GO:0055114| oxidation-reduction process CYP3A5;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1 29951:[DB06728 DB00286] DB06728|Aniline KLK1;ALB;CYP2E1 DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0043252| sodium-independent organic anion transport SLC22A11;SLCO4A1;SLCO1A2;SLCO3A1;SLCO1B1;SLC22A8;SLCO1B3;SLCO2B1;ALB;SLCO1C1;SLC22A10;SLC22A6 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLC51A;ABCC3;SLCO1C1;SLCO2B1;ALB;SLC51B;SLC10A1;SLCO1B1;SLCO1B3;SLCO1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0055114| oxidation-reduction process ABCC4;CYP3A4;CYP2E1;CYP1A2 GO:0042493| response to drug ABCC1;COMT;ABCB1;ABCC2;ABCG2;CYP1A2;CYP2E1;ABCC4 29952:[DB06728 DB00811] DB06728|Aniline KLK1;ALB;CYP2E1 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0055114| oxidation-reduction process IMPDH1;CYP2E1;IMPDH2 GO:0017144| drug metabolic process NT5C2;CYP2E1 GO:0006898| receptor-mediated endocytosis ENPP1;ALB 29953:[DB06728 DB05395] DB06728|Aniline KLK1;ALB;CYP2E1 DB05395|Amibegron ADRB3 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB3 29954:[DB06728 DB08098] DB06728|Aniline KLK1;ALB;CYP2E1 DB08098|{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 29955:[DB06728 DB00577] DB06728|Aniline KLK1;ALB;CYP2E1 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways GO:0015721| bile acid and bile salt transport SLC10A2;ALB GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A6;ALB 29956:[DB06728 DB04468] DB06728|Aniline KLK1;ALB;CYP2E1 DB04468|Afimoxifene ESR2;ESRRG;ESR1;TFF1;ESRRA;NR1I2;SHBG common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;NR1I2 GO:0008202| steroid metabolic process NR1I2;CYP2E1 29957:[DB06728 DB00699] DB06728|Aniline KLK1;ALB;CYP2E1 DB00699|Nicergoline ADRA1A;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;ADRA1A GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 29958:[DB06728 DB01433] DB06728|Aniline KLK1;ALB;CYP2E1 DB01433|Methadyl acetate OPRM1 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1 29959:[DB06728 DB01171] DB06728|Aniline KLK1;ALB;CYP2E1 DB01171|Moclobemide MAOA;MAOA;MAOB;MAOB;MAOA;MAOB;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;MAOA;CYP2D6;CYP2C19;CYP2C9;MAOB GO:0042493| response to drug CYP2E1;MAOB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C9;CYP2E1 GO:0045471| response to ethanol MAOB;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP2E1 29960:[DB06728 DB05678] DB06728|Aniline KLK1;ALB;CYP2E1 DB05678|SLx-4090 MTTP common genes common pathways 29961:[DB06728 DB01397] DB06728|Aniline KLK1;ALB;CYP2E1 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| PTGS2;PTGS1;ALB 29962:[DB06728 DB00532] DB06728|Aniline KLK1;ALB;CYP2E1 DB00532|Mephenytoin SCN5A;NR1I2;CYP2C19;CYP2B6;CYP1A2;CYP2D6;CYP2C8;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2;CYP2C9;NR1I2;CYP2B6;CYP2D6;CYP2C8;CYP2C19 GO:0008202| steroid metabolic process NR1I2;CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP2D6;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C8;CYP2C19;CYP2B6;CYP2C9 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2B6;CYP2C8;CYP2C19 29963:[DB06728 DB06755] DB06728|Aniline KLK1;ALB;CYP2E1 DB06755|Beta carotene BCO1;VLDLR;RBP1;RBP2;RBP3;RBP4;RBP5 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;VLDLR GO:0045471| response to ethanol RBP4;CYP2E1 GO:0006508| proteolysis KLK1;RBP3 GO:0008202| steroid metabolic process VLDLR;CYP2E1 GO:0055114| oxidation-reduction process BCO1;CYP2E1 29964:[DB06728 DB01017] DB06728|Aniline KLK1;ALB;CYP2E1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0006508| proteolysis MMP9;CASP1;KLK1;CASP3 GO:0002576| platelet degranulation ALB;VEGFA GO:0043066| negative regulation of apoptotic process MMP9;ALB;VEGFA;CASP3 GO:0042493| response to drug CYP2E1;CASP3 GO:0055114| oxidation-reduction process ALOX5;CYP2E1;CYCS GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLC22A7;SLC22A11 29965:[DB06728 DB02871] DB06728|Aniline KLK1;ALB;CYP2E1 DB02871|3-Butylthiolane 1-Oxide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1C 29966:[DB06728 DB01149] DB06728|Aniline KLK1;ALB;CYP2E1 DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP3A7;CYP2E1;CYP3A4;CYP2D6;CYP3A5 GO:0042493| response to drug SLC6A4;CYP2E1;HTR2A;HTR2C;SLC6A3;ABCB1;ADRA1A;SLC6A2 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;ABCB11;SLCO1B3 GO:0008202| steroid metabolic process CYP3A5;CYP2D6;CYP2E1;CYP3A4;CYP3A7 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1B3 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP3A7;CYP2E1;CYP3A4 29967:[DB06728 DB07397] DB06728|Aniline KLK1;ALB;CYP2E1 DB07397|(5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide MMP8 common genes common pathways GO:0006508| proteolysis MMP8;KLK1 29968:[DB06728 DB03283] DB06728|Aniline KLK1;ALB;CYP2E1 DB03283|beta-L-fucose ACHE common genes common pathways 29969:[DB06728 DB03712] DB06728|Aniline KLK1;ALB;CYP2E1 DB03712|RU85053 SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 29970:[DB06728 DB04203] DB06728|Aniline KLK1;ALB;CYP2E1 DB04203|3-Mercuri-4-Aminobenzenesulfonamide CA2 common genes common pathways 29971:[DB06728 DB01728] DB06728|Aniline KLK1;ALB;CYP2E1 DB01728|3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-Glycerol RHO common genes common pathways 29972:[DB06728 DB03417] DB06728|Aniline KLK1;ALB;CYP2E1 DB03417|1-(4-Tert-Butylcarbamoyl-Piperazine-1-Carbonyl)-3-(3-Guanidino-Propyl)-4-Oxo-Azetidine-2-Carboxylic Acid PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 29973:[DB06728 DB02391] DB06728|Aniline KLK1;ALB;CYP2E1 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways GO:0042493| response to drug CYP2E1;PNP 29974:[DB06728 DB02020] DB06728|Aniline KLK1;ALB;CYP2E1 DB02020|Alrestatin AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 29975:[DB06728 DB02497] DB06728|Aniline KLK1;ALB;CYP2E1 DB02497|L-Alpha-Glycerophosphorylserine ANXA5 common genes common pathways GO:0002576| platelet degranulation ALB;ANXA5 GO:0043066| negative regulation of apoptotic process ANXA5;ALB 29976:[DB06728 DB14498] DB06728|Aniline KLK1;ALB;CYP2E1 DB14498|Potassium acetate ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 29977:[DB06728 DB05478] DB06728|Aniline KLK1;ALB;CYP2E1 DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 29978:[DB06728 DB00456] DB06728|Aniline KLK1;ALB;CYP2E1 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A7;SLC22A11;SLC22A8;ALB;SLC22A6 GO:0098869| ALB 29979:[DB06728 DB01178] DB06728|Aniline KLK1;ALB;CYP2E1 DB01178|Chlormezanone TSPO common genes common pathways GO:0008202| steroid metabolic process TSPO;CYP2E1 GO:0042493| response to drug CYP2E1;TSPO 29980:[DB06728 DB07346] DB06728|Aniline KLK1;ALB;CYP2E1 DB07346|4-(2-aminoethyl)-2-ethylphenol BACE1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;BACE1 GO:0006508| proteolysis BACE1;KLK1 29981:[DB06728 DB03214] DB06728|Aniline KLK1;ALB;CYP2E1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways GO:0055114| oxidation-reduction process IL4I1;CYP2E1 29982:[DB06728 DB06987] DB06728|Aniline KLK1;ALB;CYP2E1 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;LTF GO:0044267| cellular protein metabolic process ALB;LTF GO:0006508| proteolysis LTF;KLK1 GO:0001895| retina homeostasis LTF;ALB 29983:[DB06728 DB11623] DB06728|Aniline KLK1;ALB;CYP2E1 DB11623|Candoxatrilat MME common genes common pathways GO:0006508| proteolysis KLK1;MME 29984:[DB06728 DB02299] DB06728|Aniline KLK1;ALB;CYP2E1 DB02299|Arginineamide KCNA4 common genes common pathways 29985:[DB06728 DB11582] DB06728|Aniline KLK1;ALB;CYP2E1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 29986:[DB06728 DB03062] DB06728|Aniline KLK1;ALB;CYP2E1 DB03062|(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone NMT1;NMT1 common genes common pathways 29987:[DB06728 DB08799] DB06728|Aniline KLK1;ALB;CYP2E1 DB08799|Antazoline HRH1 common genes common pathways 29988:[DB06728 DB03934] DB06728|Aniline KLK1;ALB;CYP2E1 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways GO:0055114| oxidation-reduction process CYCS;CYP2E1 29989:[DB06728 DB06081] DB06728|Aniline KLK1;ALB;CYP2E1 DB06081|Caplacizumab VWF common genes common pathways GO:0002576| platelet degranulation VWF;ALB 29990:[DB06728 DB12637] DB06728|Aniline KLK1;ALB;CYP2E1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways 29991:[DB06728 DB07000] DB06728|Aniline KLK1;ALB;CYP2E1 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways GO:0043066| negative regulation of apoptotic process BRAF;ALB 29992:[DB06728 DB07070] DB06728|Aniline KLK1;ALB;CYP2E1 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways GO:0043066| negative regulation of apoptotic process PPARD;ALB 29993:[DB06728 DB05447] DB06728|Aniline KLK1;ALB;CYP2E1 DB05447|AVI-4557 HNF4A common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;HNF4A 29994:[DB06728 DB07485] DB06728|Aniline KLK1;ALB;CYP2E1 DB07485|4,4'-cyclohexane-1,1-diyldiphenol ESRRG common genes common pathways 29995:[DB06728 DB09298] DB06728|Aniline KLK1;ALB;CYP2E1 DB09298|Silibinin A UGT1A1;SLC22A6;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;SLC22A6;ALB;SLCO2B1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1B3;SLCO1B1 GO:0042493| response to drug UGT1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 29996:[DB06728 DB01190] DB06728|Aniline KLK1;ALB;CYP2E1 DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 29997:[DB06728 DB00982] DB06728|Aniline KLK1;ALB;CYP2E1 DB00982|Isotretinoin RARA common genes common pathways GO:0045471| response to ethanol CYP2E1;RARA GO:0043066| negative regulation of apoptotic process ALB;RARA 29998:[DB06728 DB05107] DB06728|Aniline KLK1;ALB;CYP2E1 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways GO:0045471| response to ethanol CYP2E1;G6PD GO:0055114| oxidation-reduction process CYP2E1;G6PD 29999:[DB06728 DB01990] DB06728|Aniline KLK1;ALB;CYP2E1 DB01990|Cholesterol sulfate RORA common genes common pathways GO:0006805| xenobiotic metabolic process RORA;CYP2E1 30000:[DB06728 DB03682] DB06728|Aniline KLK1;ALB;CYP2E1 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 30001:[DB06728 DB02868] DB06728|Aniline KLK1;ALB;CYP2E1 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways GO:0002576| platelet degranulation CALM1;ALB 30002:[DB06728 DB01328] DB06728|Aniline KLK1;ALB;CYP2E1 DB01328|Cefonicid mrcA;ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB 30003:[DB06728 DB04817] DB06728|Aniline KLK1;ALB;CYP2E1 DB04817|Metamizole PTGS1;CYP2B6;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2B6;PTGS1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2B6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2B6 GO:0098869| PTGS1;ALB GO:0055114| oxidation-reduction process CYP2B6;CYP2E1;CYP3A4;PTGS1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 30004:[DB06728 DB08789] DB06728|Aniline KLK1;ALB;CYP2E1 DB08789|2-AMINO-4-(2,4-DICHLOROPHENYL)-N-ETHYLTHIENO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 30005:[DB06728 DB00202] DB06728|Aniline KLK1;ALB;CYP2E1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 30006:[DB06728 DB13178] DB06728|Aniline KLK1;ALB;CYP2E1 DB13178|Inositol SLC5A3 common genes common pathways 30007:[DB06728 DB12670] DB06728|Aniline KLK1;ALB;CYP2E1 DB12670|Rolofylline ADORA1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADORA1 30008:[DB06728 DB03591] DB06728|Aniline KLK1;ALB;CYP2E1 DB03591|RU82209 SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;SRC 30009:[DB06728 DB05243] DB06728|Aniline KLK1;ALB;CYP2E1 DB05243|XL019 JAK2 common genes common pathways 30010:[DB06728 DB11692] DB06728|Aniline KLK1;ALB;CYP2E1 DB11692|Pavinetant TACR3 common genes common pathways 30011:[DB06728 DB07157] DB06728|Aniline KLK1;ALB;CYP2E1 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways GO:0006508| proteolysis CPB1;KLK1 30012:[DB06728 DB06282] DB06728|Aniline KLK1;ALB;CYP2E1 DB06282|Levocetirizine HRH1 common genes common pathways 30013:[DB06728 DB01404] DB06728|Aniline KLK1;ALB;CYP2E1 DB01404|Ginseng IL6;PTGS2;AHR common genes common pathways GO:0006805| xenobiotic metabolic process AHR;CYP2E1 GO:0043687| post-translational protein modification ALB;IL6 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;IL6;PTGS2 GO:0044267| cellular protein metabolic process ALB;IL6 GO:0098869| ALB;PTGS2 30014:[DB06728 DB08006] DB06728|Aniline KLK1;ALB;CYP2E1 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP2E1 GO:0042493| response to drug DHODH;CYP2E1 30015:[DB06728 DB06735] DB06728|Aniline KLK1;ALB;CYP2E1 DB06735|Enclomiphene CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 30016:[DB06728 DB01364] DB06728|Aniline KLK1;ALB;CYP2E1 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE;SLC6A2;ADRA1A 30017:[DB06728 DB06697] DB06728|Aniline KLK1;ALB;CYP2E1 DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP3A5;CYP2B6;CYP2C9;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP3A5;CYP2B6;CYP2C9 30018:[DB06728 DB08749] DB06728|Aniline KLK1;ALB;CYP2E1 DB08749|3-(2-AMINO-6-BENZOYLQUINAZOLIN-3(4H)-YL)-N-CYCLOHEXYL-N-METHYLPROPANAMIDE BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process ALB;BACE1 30019:[DB06728 DB03769] DB06728|Aniline KLK1;ALB;CYP2E1 DB03769|D-Eritadenine AHCY common genes common pathways 30020:[DB06728 DB04682] DB06728|Aniline KLK1;ALB;CYP2E1 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 30021:[DB06728 DB07787] DB06728|Aniline KLK1;ALB;CYP2E1 DB07787|5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE PARP1 common genes common pathways 30022:[DB06728 DB02426] DB06728|Aniline KLK1;ALB;CYP2E1 DB02426|Carboxyatractyloside SLC25A4 common genes common pathways 30023:[DB06728 DB06997] DB06728|Aniline KLK1;ALB;CYP2E1 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways 30024:[DB06728 DB07966] DB06728|Aniline KLK1;ALB;CYP2E1 DB07966|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process ALB;SRC 30025:[DB06728 DB05464] DB06728|Aniline KLK1;ALB;CYP2E1 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;NFKB1 30026:[DB06728 DB04381] DB06728|Aniline KLK1;ALB;CYP2E1 DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP2E1 30027:[DB06728 DB01095] DB06728|Aniline KLK1;ALB;CYP2E1 DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2C8;CYP2D6 GO:0045471| response to ethanol UGT1A1;HMGCR;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;HMGCR;CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP2B6;CYP2C9;CYP1A1 GO:0042493| response to drug CYP2E1;ABCC2;CYP1A1;UGT1A1 GO:0043066| negative regulation of apoptotic process ALB;HMGCR GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP1A1;CYP2C9;CYP2B6;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1B1;SLCO1B3 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C19;UGT1A1;CYP2C9;CYP1A1;CYP2B6;UGT1A3;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process UGT2B7;CYP3A4;CYP2E1;HMGCR;CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP2B6;CYP1A1;CYP2C9;UGT1A1 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB;SLCO2B1 30028:[DB06728 DB01644] DB06728|Aniline KLK1;ALB;CYP2E1 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;GSR GO:0098869| GSR;ALB 30029:[DB06728 DB03991] DB06728|Aniline KLK1;ALB;CYP2E1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways 30030:[DB06728 DB08350] DB06728|Aniline KLK1;ALB;CYP2E1 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways 30031:[DB06728 DB08743] DB06728|Aniline KLK1;ALB;CYP2E1 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 30032:[DB06728 DB05200] DB06728|Aniline KLK1;ALB;CYP2E1 DB05200|AT2220 GAA common genes common pathways 30033:[DB06728 DB02875] DB06728|Aniline KLK1;ALB;CYP2E1 DB02875|CRA_1802 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30034:[DB06728 DB01472] DB06728|Aniline KLK1;ALB;CYP2E1 DB01472|4-Methoxyamphetamine SLC6A3;SLC6A4;SLC18A2;ADRA1A;ADRA2A;MAOA;MAOB;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process MAOA;CYP2E1;MAOB;CYP2D6 GO:0042493| response to drug ADRA1A;SLC6A3;MAOB;SLC6A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0045471| response to ethanol SLC6A3;MAOB;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 30035:[DB06728 DB14707] DB06728|Aniline KLK1;ALB;CYP2E1 DB14707|Cemiplimab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PDCD1;ALB 30036:[DB06728 DB12960] DB06728|Aniline KLK1;ALB;CYP2E1 DB12960|INCB-9471 CCR5 common genes common pathways 30037:[DB06728 DB14063] DB06728|Aniline KLK1;ALB;CYP2E1 DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 30038:[DB06728 DB04953] DB06728|Aniline KLK1;ALB;CYP2E1 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;UGT1A9;NAT2 GO:0042493| response to drug UGT1A1;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1 GO:0017144| drug metabolic process UGT1A9;UGT1A4;UGT1A1;UGT1A3;CYP2E1 30039:[DB06728 DB09333] DB06728|Aniline KLK1;ALB;CYP2E1 DB09333|Iopodic acid DIO3;ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process DIO3;CYP2E1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 30040:[DB06728 DB11571] DB06728|Aniline KLK1;ALB;CYP2E1 DB11571|Human Thrombin F5;F8;F11;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0044267| cellular protein metabolic process ALB;F5;FGA;FGG GO:0043687| post-translational protein modification FGG;ALB;F5;FGA GO:0055114| oxidation-reduction process F8;CYP2E1 GO:0002576| platelet degranulation F8;FGG;F13A1;ALB;FGA;F5;FGB GO:0006508| proteolysis KLK1;F11 30041:[DB06728 DB06707] DB06728|Aniline KLK1;ALB;CYP2E1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways 30042:[DB06728 DB09143] DB06728|Aniline KLK1;ALB;CYP2E1 DB09143|Sonidegib SMO;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;SMO GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 30043:[DB06728 DB00293] DB06728|Aniline KLK1;ALB;CYP2E1 DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0045471| response to ethanol TYMS;CYP2E1 GO:0042493| response to drug CYP2E1;TYMS 30044:[DB06728 DB07602] DB06728|Aniline KLK1;ALB;CYP2E1 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 30045:[DB06728 DB04215] DB06728|Aniline KLK1;ALB;CYP2E1 DB04215|CRA_9076 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30046:[DB06728 DB12615] DB06728|Aniline KLK1;ALB;CYP2E1 DB12615|Plazomicin rpsN;rpsK;SLC47A1;SLC47A2 common genes common pathways 30047:[DB06728 DB08818] DB06728|Aniline KLK1;ALB;CYP2E1 DB08818|Hyaluronic acid CD44;ICAM1;HMMR;NCAN;VCAN;C1QBP;HAPLN1;HAPLN3;HAPLN4;HABP2;LAYN;STAB2;TNFAIP6;IMPG2;HABP4 common genes common pathways GO:0044267| cellular protein metabolic process VCAN;ALB GO:0042493| response to drug CYP2E1;ICAM1 GO:0043687| post-translational protein modification ALB;VCAN GO:0055114| oxidation-reduction process CYP2E1;STAB2 GO:0043066| negative regulation of apoptotic process ALB;CD44 GO:0002576| platelet degranulation HABP4;ALB GO:0006898| receptor-mediated endocytosis ALB;STAB2 GO:0006508| proteolysis KLK1;HABP2 GO:0045471| response to ethanol CYP2E1;ICAM1 30048:[DB06728 DB00320] DB06728|Aniline KLK1;ALB;CYP2E1 DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;HTR1B;HTR2B;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol HTR1B;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30049:[DB06728 DB07609] DB06728|Aniline KLK1;ALB;CYP2E1 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6 GO:0008202| steroid metabolic process CYP2A6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2A6 30050:[DB06728 DB00835] DB06728|Aniline KLK1;ALB;CYP2E1 DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2B6;CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8;CYP2B6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8;CYP2B6 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 30051:[DB06728 DB03323] DB06728|Aniline KLK1;ALB;CYP2E1 DB03323|Maltose AMY2B;aglA common genes common pathways 30052:[DB06728 DB04617] DB06728|Aniline KLK1;ALB;CYP2E1 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways 30053:[DB06728 DB00576] DB06728|Aniline KLK1;ALB;CYP2E1 DB00576|Sulfamethizole CYP2C9;ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 30054:[DB06728 DB08021] DB06728|Aniline KLK1;ALB;CYP2E1 DB08021|5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide MAPK10 common genes common pathways 30055:[DB06728 DB00718] DB06728|Aniline KLK1;ALB;CYP2E1 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0042493| response to drug AK4;CYP2E1;ABCC4;NME1 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0043066| negative regulation of apoptotic process NME2;ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB 30056:[DB06728 DB04463] DB06728|Aniline KLK1;ALB;CYP2E1 DB04463|3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol CBR1;CBR1 common genes common pathways GO:0017144| drug metabolic process CBR1;CYP2E1 GO:0055114| oxidation-reduction process CBR1;CYP2E1 30057:[DB06728 DB00368] DB06728|Aniline KLK1;ALB;CYP2E1 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0055114| oxidation-reduction process PAH;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A2;ADRA1A GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB 30058:[DB06728 DB04759] DB06728|Aniline KLK1;ALB;CYP2E1 DB04759|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways GO:0006508| proteolysis KLK1;MMP13 GO:0044267| cellular protein metabolic process ALB;MMP13 30059:[DB06728 DB08238] DB06728|Aniline KLK1;ALB;CYP2E1 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways 30060:[DB06728 DB03535] DB06728|Aniline KLK1;ALB;CYP2E1 DB03535|Z-Pro-Prolinal PREP common genes common pathways GO:0006508| proteolysis PREP;KLK1 30061:[DB06728 DB00151] DB06728|Aniline KLK1;ALB;CYP2E1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0045471| response to ethanol MGMT;CYP2E1;CDO1 GO:0010243| response to organic nitrogen CDO1;CYP2E1 GO:0055114| oxidation-reduction process CBS;CYP2E1;CDO1 GO:0042493| response to drug GCLM;CYP2E1;MGMT GO:0043066| negative regulation of apoptotic process ALB;GCLC;CTH;MGMT 30062:[DB06728 DB02751] DB06728|Aniline KLK1;ALB;CYP2E1 DB02751|Glycocyamine GAMT common genes common pathways 30063:[DB06728 DB03185] DB06728|Aniline KLK1;ALB;CYP2E1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 30064:[DB06728 DB03453] DB06728|Aniline KLK1;ALB;CYP2E1 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways GO:0045471| response to ethanol CYP2E1;IL2 GO:0043066| negative regulation of apoptotic process ALB;IL2 30065:[DB06728 DB09292] DB06728|Aniline KLK1;ALB;CYP2E1 DB09292|Sacubitril MME;SLCO1B1;SLCO1B3 common genes common pathways GO:0006508| proteolysis MME;KLK1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB 30066:[DB06728 DB08024] DB06728|Aniline KLK1;ALB;CYP2E1 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 30067:[DB06728 DB09038] DB06728|Aniline KLK1;ALB;CYP2E1 DB09038|Empagliflozin SLC5A2 common genes common pathways 30068:[DB06728 DB07586] DB06728|Aniline KLK1;ALB;CYP2E1 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways 30069:[DB06728 DB04416] DB06728|Aniline KLK1;ALB;CYP2E1 DB04416|R-2-{[4'-Methoxy-(1,1'-Biphenyl)-4-Yl]-Sulfonyl}-Amino-6-Methoxy-Hex-4-Ynoic Acid MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 30070:[DB06728 DB06958] DB06728|Aniline KLK1;ALB;CYP2E1 DB06958|5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 30071:[DB06728 DB07133] DB06728|Aniline KLK1;ALB;CYP2E1 DB07133|D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process ALB;F2 30072:[DB06728 DB00074] DB06728|Aniline KLK1;ALB;CYP2E1 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FCGR1A;FCGR2B GO:0006508| proteolysis C1R;C1QB;C1QC;C1S;C1QA;KLK1 GO:0043066| negative regulation of apoptotic process IL2RB;ALB 30073:[DB06728 DB02894] DB06728|Aniline KLK1;ALB;CYP2E1 DB02894|Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester CA2 common genes common pathways 30074:[DB06728 DB00755] DB06728|Aniline KLK1;ALB;CYP2E1 DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes ALB common pathways GO:0006508| proteolysis LCN1;KLK1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;RBP4;RARA GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2C9;CYP2B6;CYP2C18;CYP3A4;CYP2E1;CYP3A7;CYP26A1;CYP26B1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB;LCN1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0042493| response to drug CYP2E1;CYP1A1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A5;ALDH1A2;CYP2C8;CYP2C9;CYP1A1;CYP2B6;CYP26C1;CYP2C18;ALDH1A1;CYP2E1;CYP3A4;CYP2A6;CYP26A1;CYP4A11;CYP3A7;CYP26B1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A1;CYP2B6;CYP2C8;CYP4A11;CYP2E1;CYP2A6;CYP2C18 GO:0043066| negative regulation of apoptotic process RARG;RARA;ALB;RARB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;RXRA GO:0009267| cellular response to starvation PDK4;ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2B6;CYP1A1;CYP2C9;CYP2C8;CYP3A5;CYP3A7;CYP2A6;CYP3A4;CYP2E1 GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6;CYP2C8;CYP1A1;CYP2C9;CYP2B6 30075:[DB06728 DB03516] DB06728|Aniline KLK1;ALB;CYP2E1 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0017144| drug metabolic process AOX1;CYP2E1 GO:0055114| oxidation-reduction process AOX1;DPYD;CYP2E1;XDH 30076:[DB06728 DB00749] DB06728|Aniline KLK1;ALB;CYP2E1 DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;RXRA GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB;PTGS2;PTGS1 GO:0017144| drug metabolic process CYP2C9;UGT1A9;UGT1A3;CYP2E1;UGT1A10 GO:0008202| steroid metabolic process CYP2C9;CYP2E1;UGT2B7 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1;CYP2C9 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0002576| platelet degranulation ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C9;PTGS1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 30077:[DB06728 DB07330] DB06728|Aniline KLK1;ALB;CYP2E1 DB07330|trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium PARP1 common genes common pathways 30078:[DB06728 DB03128] DB06728|Aniline KLK1;ALB;CYP2E1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways 30079:[DB06728 DB08888] DB06728|Aniline KLK1;ALB;CYP2E1 DB08888|Ocriplasmin FN1;A2M;SERPINF2 common genes common pathways GO:0044267| cellular protein metabolic process FN1;ALB GO:0043687| post-translational protein modification ALB;FN1 GO:0002576| platelet degranulation SERPINF2;A2M;ALB;FN1 30080:[DB06728 DB03824] DB06728|Aniline KLK1;ALB;CYP2E1 DB03824|7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline PNMT common genes common pathways 30081:[DB06728 DB01306] DB06728|Aniline KLK1;ALB;CYP2E1 DB01306|Insulin Aspart INSR common genes common pathways 30082:[DB06728 DB14570] DB06728|Aniline KLK1;ALB;CYP2E1 DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30083:[DB06728 DB05773] DB06728|Aniline KLK1;ALB;CYP2E1 DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 30084:[DB06728 DB02198] DB06728|Aniline KLK1;ALB;CYP2E1 DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways GO:0098869| PTGS1;ALB GO:0055114| oxidation-reduction process CYP2E1;PTGS1 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 30085:[DB06728 DB00148] DB06728|Aniline KLK1;ALB;CYP2E1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways 30086:[DB06728 DB07780] DB06728|Aniline KLK1;ALB;CYP2E1 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways GO:0043687| post-translational protein modification ALB;RABGGTA;RABGGTB GO:0008202| steroid metabolic process FDPS;CYP2E1 30087:[DB06728 DB08053] DB06728|Aniline KLK1;ALB;CYP2E1 DB08053|1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process SRC;ALB 30088:[DB06728 DB06090] DB06728|Aniline KLK1;ALB;CYP2E1 DB06090|Bradanicline CHRNA7 common genes common pathways 30089:[DB06728 DB01614] DB06728|Aniline KLK1;ALB;CYP2E1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes ALB common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug HTR2A;CYP2E1;DRD1;DRD2;ADRA1A GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 30090:[DB06728 DB13151] DB06728|Aniline KLK1;ALB;CYP2E1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0006508| proteolysis KLK1;F2;F7;F9;F10 GO:0044267| cellular protein metabolic process ALB;F5;F2;FGA GO:0055114| oxidation-reduction process CYP2E1;F8 GO:0043687| post-translational protein modification F5;FGA;ALB GO:0002576| platelet degranulation F8;F13A1;ALB;FGA;F5;FGB 30091:[DB06728 DB00475] DB06728|Aniline KLK1;ALB;CYP2E1 DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;GABRG3 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 30092:[DB06728 DB01431] DB06728|Aniline KLK1;ALB;CYP2E1 DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30093:[DB06728 DB01610] DB06728|Aniline KLK1;ALB;CYP2E1 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways 30094:[DB06728 DB11914] DB06728|Aniline KLK1;ALB;CYP2E1 DB11914|Lebrikizumab IL13;IL13 common genes common pathways GO:0045471| response to ethanol IL13;CYP2E1 30095:[DB06728 DB04530] DB06728|Aniline KLK1;ALB;CYP2E1 DB04530|S,S-(2-Hydroxyethyl)Thiocysteine SERPINB5;PDE1B;SNX3;CYTH2;thyA;PDE4B;TYMS;PRKACA;PIM1;ARG1;icd;hemB common genes common pathways GO:0045471| response to ethanol TYMS;CYP2E1 GO:0042493| response to drug CYP2E1;ARG1;TYMS GO:0043066| negative regulation of apoptotic process ALB;PIM1 30096:[DB06728 DB01382] DB06728|Aniline KLK1;ALB;CYP2E1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC8 30097:[DB06728 DB04707] DB06728|Aniline KLK1;ALB;CYP2E1 DB04707|Hydroxyfasudil ROCK1;PRKACA;PKIA common genes common pathways 30098:[DB06728 DB07448] DB06728|Aniline KLK1;ALB;CYP2E1 DB07448|(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid LAP3 common genes common pathways GO:0006508| proteolysis LAP3;KLK1 30099:[DB06728 DB12442] DB06728|Aniline KLK1;ALB;CYP2E1 DB12442|Alvespimycin HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 30100:[DB06728 DB03279] DB06728|Aniline KLK1;ALB;CYP2E1 DB03279|Dodecyl-Alpha-D-Maltoside RARG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 30101:[DB06728 DB08836] DB06728|Aniline KLK1;ALB;CYP2E1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0006508| proteolysis KLK1;ACE GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB 30102:[DB06728 DB00165] DB06728|Aniline KLK1;ALB;CYP2E1 DB00165|Pyridoxine PDXK;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 GO:0042493| response to drug CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1 GO:0017144| drug metabolic process CYP1A1;CYP2E1 30103:[DB06728 DB07783] DB06728|Aniline KLK1;ALB;CYP2E1 DB07783|1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(3-PHENYLPROPANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0042493| response to drug CYP2E1;ADA 30104:[DB06728 DB00714] DB06728|Aniline KLK1;ALB;CYP2E1 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0045471| response to ethanol CYP2E1;HTR1B;DRD2;DRD3 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0042493| response to drug CYP2E1;HTR2A;DRD1;DRD3;HTR2C;HTR2B;DRD2;HTR1B 30105:[DB06728 DB03495] DB06728|Aniline KLK1;ALB;CYP2E1 DB03495|4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose AMY2A;AMY2A common genes common pathways 30106:[DB06728 DB01600] DB06728|Aniline KLK1;ALB;CYP2E1 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0098869| ALB;PTGS2;PTGS1 30107:[DB06728 DB09099] DB06728|Aniline KLK1;ALB;CYP2E1 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 30108:[DB06728 DB03223] DB06728|Aniline KLK1;ALB;CYP2E1 DB03223|Diphthamide EEF2 common genes common pathways GO:0042493| response to drug CYP2E1;EEF2 GO:0045471| response to ethanol EEF2;CYP2E1 30109:[DB06728 DB06843] DB06728|Aniline KLK1;ALB;CYP2E1 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug GNAS;CYP2E1 30110:[DB06728 DB08675] DB06728|Aniline KLK1;ALB;CYP2E1 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PTGIS 30111:[DB06728 DB07281] DB06728|Aniline KLK1;ALB;CYP2E1 DB07281|N~3~-BENZYLPYRIDINE-2,3-DIAMINE BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process ALB;BACE1 30112:[DB06728 DB03595] DB06728|Aniline KLK1;ALB;CYP2E1 DB03595|CRA_9785 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 30113:[DB06728 DB00926] DB06728|Aniline KLK1;ALB;CYP2E1 DB00926|Etretinate RARA;RXRA;RARB;RXRG;RXRB;RARG;CYP19A1;CYP26A1;CRABP1 common genes common pathways GO:0045471| response to ethanol CYP2E1;RARA GO:0006805| xenobiotic metabolic process CYP26A1;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;RXRA GO:0043066| negative regulation of apoptotic process RARB;ALB;RARA;RARG GO:0055114| oxidation-reduction process CYP26A1;CYP2E1;CYP19A1 30114:[DB06728 DB11611] DB06728|Aniline KLK1;ALB;CYP2E1 DB11611|Lifitegrast ITGAL;CYP2C9;SLCO1A2;SLCO2B1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;SLCO2B1 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 30115:[DB06728 DB00039] DB06728|Aniline KLK1;ALB;CYP2E1 DB00039|Palifermin FGFR2;NRP1;FGFR1;FGFR4;FGFR3;HSPG2 common genes common pathways GO:0045471| response to ethanol CYP2E1;FGFR2 GO:0006898| receptor-mediated endocytosis ALB;HSPG2 GO:0044267| cellular protein metabolic process ALB;HSPG2 30116:[DB06728 DB02966] DB06728|Aniline KLK1;ALB;CYP2E1 DB02966|Fluoro-Willardiine GRIA2 common genes common pathways 30117:[DB06728 DB06699] DB06728|Aniline KLK1;ALB;CYP2E1 DB06699|Degarelix GNRHR common genes common pathways 30118:[DB06728 DB00176] DB06728|Aniline KLK1;ALB;CYP2E1 DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes CYP2E1 common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP3A5 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP2E1;CYP1A2 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8;CYP2C19;CYP2B6;CYP2C9;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP1A1;CYP2B6 GO:0042493| response to drug CYP1A2;CYP2E1;SLC6A4;CYP1A1;ABCB1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP1A1;CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0015721| bile acid and bile salt transport ABCB11;ALB 30119:[DB06728 DB05687] DB06728|Aniline KLK1;ALB;CYP2E1 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0042493| response to drug CYP2E1;HTR2A;DRD2 30120:[DB06728 DB03314] DB06728|Aniline KLK1;ALB;CYP2E1 DB03314|Fluorotryptophane TPI1;GSTM1 common genes common pathways 30121:[DB06728 DB01400] DB06728|Aniline KLK1;ALB;CYP2E1 DB01400|Neostigmine ACHE;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 30122:[DB06728 DB04972] DB06728|Aniline KLK1;ALB;CYP2E1 DB04972|Canfosfamide GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0098869| GSTP1;ALB 30123:[DB06728 DB04774] DB06728|Aniline KLK1;ALB;CYP2E1 DB04774|Reidispongiolide A ACTA1 common genes common pathways 30124:[DB06728 DB06822] DB06728|Aniline KLK1;ALB;CYP2E1 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0006508| proteolysis KLK1;ADAMTS4 GO:0044267| cellular protein metabolic process SERPINC1;ALB GO:0043687| post-translational protein modification SERPINC1;ALB 30125:[DB06728 DB00200] DB06728|Aniline KLK1;ALB;CYP2E1 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;CUBN;AMN GO:0008202| steroid metabolic process CYP2E1;CUBN GO:0055114| oxidation-reduction process MMACHC;CYP2E1;MTRR 30126:[DB06728 DB05578] DB06728|Aniline KLK1;ALB;CYP2E1 DB05578|Ramucirumab KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 30127:[DB06728 DB07187] DB06728|Aniline KLK1;ALB;CYP2E1 DB07187|6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 30128:[DB06728 DB03974] DB06728|Aniline KLK1;ALB;CYP2E1 DB03974|L-Homoarginine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 30129:[DB06728 DB04089] DB06728|Aniline KLK1;ALB;CYP2E1 DB04089|AL5300 CA2 common genes common pathways 30130:[DB06728 DB08165] DB06728|Aniline KLK1;ALB;CYP2E1 DB08165|indane-5-sulfonamide CA2 common genes common pathways 30131:[DB06728 DB09564] DB06728|Aniline KLK1;ALB;CYP2E1 DB09564|Insulin Degludec INSR common genes common pathways 30132:[DB06728 DB14517] DB06728|Aniline KLK1;ALB;CYP2E1 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes KLK1;ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process TF;APP;ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0042493| response to drug CYP2E1;ATP1A1 GO:0043687| post-translational protein modification TF;APP;ALB GO:0002576| platelet degranulation APP;ALB;TF GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB;TF GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006508| proteolysis KLK1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 30133:[DB06728 DB01212] DB06728|Aniline KLK1;ALB;CYP2E1 DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport SLC22A11;SLC22A8;ALB;SLC22A6 GO:0009267| cellular response to starvation GLUL;ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 30134:[DB06728 DB07660] DB06728|Aniline KLK1;ALB;CYP2E1 DB07660|AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 30135:[DB06728 DB03476] DB06728|Aniline KLK1;ALB;CYP2E1 DB03476|Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 30136:[DB06728 DB11921] DB06728|Aniline KLK1;ALB;CYP2E1 DB11921|Deflazacort CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 30137:[DB06728 DB02633] DB06728|Aniline KLK1;ALB;CYP2E1 DB02633|Cibacron Blue NQO1;GSTP1 common genes common pathways GO:0098869| ALB;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB;NQO1 GO:0055114| oxidation-reduction process NQO1;CYP2E1 GO:0045471| response to ethanol CYP2E1;NQO1;GSTP1 GO:0006805| xenobiotic metabolic process NQO1;GSTP1;CYP2E1 30138:[DB06728 DB08166] DB06728|Aniline KLK1;ALB;CYP2E1 DB08166|(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 30139:[DB06728 DB06931] DB06728|Aniline KLK1;ALB;CYP2E1 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 30140:[DB06728 DB01289] DB06728|Aniline KLK1;ALB;CYP2E1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 30141:[DB06728 DB00762] DB06728|Aniline KLK1;ALB;CYP2E1 DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP3A7;CES1;CYP3A4;CYP2E1;UGT1A9;CYP2B6;CYP3A5;CES2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process UGT1A9;UGT1A1;CYP2B6;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5;UGT1A1;CYP2B6 GO:0042493| response to drug TOP1;CYP2E1;UGT1A1;BCHE;ABCC1;ABCB1;ABCG2;ABCC2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2B6 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB 30142:[DB06728 DB00357] DB06728|Aniline KLK1;ALB;CYP2E1 DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP11A1;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP19A1;CYP3A4;CYP2E1;CYP11A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 30143:[DB06728 DB08176] DB06728|Aniline KLK1;ALB;CYP2E1 DB08176|(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0042493| response to drug MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOB;CYP2E1 30144:[DB06728 DB00243] DB06728|Aniline KLK1;ALB;CYP2E1 DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 30145:[DB06728 DB13144] DB06728|Aniline KLK1;ALB;CYP2E1 DB13144|Lenograstim CSF3R common genes common pathways 30146:[DB06728 DB06191] DB06728|Aniline KLK1;ALB;CYP2E1 DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0042493| response to drug CYP2E1;ABCB1 30147:[DB06728 DB08104] DB06728|Aniline KLK1;ALB;CYP2E1 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 30148:[DB06728 DB00884] DB06728|Aniline KLK1;ALB;CYP2E1 DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 30149:[DB06728 DB01014] DB06728|Aniline KLK1;ALB;CYP2E1 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug CYP2E1;PTGS2;PPARG GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1;ALOX5 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 30150:[DB06728 DB04334] DB06728|Aniline KLK1;ALB;CYP2E1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0006805| xenobiotic metabolic process AOC3;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;AOC3 30151:[DB06728 DB14041] DB06728|Aniline KLK1;ALB;CYP2E1 DB14041|Fremanezumab CALCA;CALCB common genes common pathways 30152:[DB06728 DB07061] DB06728|Aniline KLK1;ALB;CYP2E1 DB07061|1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL NMT2 common genes common pathways 30153:[DB06728 DB05265] DB06728|Aniline KLK1;ALB;CYP2E1 DB05265|Ecabet NOXO1;ureC common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOXO1 30154:[DB06728 DB09309] DB06728|Aniline KLK1;ALB;CYP2E1 DB09309|Kitasamycin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30155:[DB06728 DB05479] DB06728|Aniline KLK1;ALB;CYP2E1 DB05479|CZEN 002 MC1R common genes common pathways 30156:[DB06728 DB00993] DB06728|Aniline KLK1;ALB;CYP2E1 DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process XDH;CYP1A2;CYP2E1 GO:0098869| ALB;GSTA1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 30157:[DB06728 DB01677] DB06728|Aniline KLK1;ALB;CYP2E1 DB01677|Fumaric Acid mdh;ME2;FAH common genes common pathways GO:0055114| oxidation-reduction process ME2;CYP2E1 30158:[DB06728 DB01056] DB06728|Aniline KLK1;ALB;CYP2E1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0098869| ALB GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP1A2;CYP2E1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 30159:[DB06728 DB04876] DB06728|Aniline KLK1;ALB;CYP2E1 DB04876|Vildagliptin DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 30160:[DB06728 DB02393] DB06728|Aniline KLK1;ALB;CYP2E1 DB02393|D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate PFKFB1 common genes common pathways 30161:[DB06728 DB00555] DB06728|Aniline KLK1;ALB;CYP2E1 DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A4;UGT1A3;CYP2E1 GO:0042493| response to drug CYP2E1;HTR2A;DRD1;GABRG3;UGT1A1;ADORA2A;ADRA1A;DRD2;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;DHFR GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;OPRK1;DRD2;HTR3A;UGT1A1 30162:[DB06728 DB08057] DB06728|Aniline KLK1;ALB;CYP2E1 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways GO:0042493| response to drug CYP2E1;LCK 30163:[DB06728 DB07766] DB06728|Aniline KLK1;ALB;CYP2E1 DB07766|(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} CAMK2A;CDK16 common genes common pathways 30164:[DB06728 DB00976] DB06728|Aniline KLK1;ALB;CYP2E1 DB00976|Telithromycin CYP3A7;CYP3A4;CYP3A5;SLCO1B1;SLCO1B3 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP3A5 30165:[DB06728 DB11077] DB06728|Aniline KLK1;ALB;CYP2E1 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0008202| steroid metabolic process SULT1A1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP4A11;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP4A11;ADH5 GO:0006898| receptor-mediated endocytosis ALB;ENPP1 GO:0006805| xenobiotic metabolic process SULT1A1;CYP2E1 30166:[DB06728 DB11487] DB06728|Aniline KLK1;ALB;CYP2E1 DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 30167:[DB06728 DB11093] DB06728|Aniline KLK1;ALB;CYP2E1 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB;CALR;SPARC GO:0006508| proteolysis KLK1;GCA;SRI;PEF1;PDCD6 GO:0045471| response to ethanol CYP2E1;SPARC GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0044267| cellular protein metabolic process CALB1;ALB;NUCB1 GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB;CADPS2 GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB;NUCB1 GO:0042493| response to drug CALR;SLC8A1;CYP2E1 GO:0002576| platelet degranulation SPARC;CALM1;ALB GO:0043066| negative regulation of apoptotic process CIB1;ALB;TPT1;RGN 30168:[DB06728 DB12110] DB06728|Aniline KLK1;ALB;CYP2E1 DB12110|m-Chlorophenylpiperazine HTR2C common genes common pathways GO:0042493| response to drug CYP2E1;HTR2C 30169:[DB06728 DB04896] DB06728|Aniline KLK1;ALB;CYP2E1 DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;GRIN2B;GRIN1;GRIN2A;GRIN3A GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug SLC6A2;GRIN2A;SLC6A4;CYP2E1 30170:[DB06728 DB08358] DB06728|Aniline KLK1;ALB;CYP2E1 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 30171:[DB06728 DB03333] DB06728|Aniline KLK1;ALB;CYP2E1 DB03333|(4-sulfamoyl-phenyl)-thiocarbamic acid O-(2-thiophen-3-yl-ethyl) ester CA2 common genes common pathways 30172:[DB06728 DB06838] DB06728|Aniline KLK1;ALB;CYP2E1 DB06838|methyl L-phenylalaninate F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 30173:[DB06728 DB01354] DB06728|Aniline KLK1;ALB;CYP2E1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 30174:[DB06728 DB03749] DB06728|Aniline KLK1;ALB;CYP2E1 DB03749|4-(1h-Imidazol-4-Yl)-3-(5-Ethyl-2,4-Dihydroxy-Phenyl)-1h-Pyrazole HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 30175:[DB06728 DB05225] DB06728|Aniline KLK1;ALB;CYP2E1 DB05225|AM103 ALOX5AP common genes common pathways 30176:[DB06728 DB11948] DB06728|Aniline KLK1;ALB;CYP2E1 DB11948|Lapachone RBP3 common genes common pathways GO:0006508| proteolysis RBP3;KLK1 30177:[DB06728 DB03672] DB06728|Aniline KLK1;ALB;CYP2E1 DB03672|9-N-Phenylmethylamino-Tacrine BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 30178:[DB06728 DB01255] DB06728|Aniline KLK1;ALB;CYP2E1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 30179:[DB06728 DB07004] DB06728|Aniline KLK1;ALB;CYP2E1 DB07004|2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide S100B common genes common pathways 30180:[DB06728 DB04327] DB06728|Aniline KLK1;ALB;CYP2E1 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0045471| response to ethanol CYP2E1;PTEN GO:0043066| negative regulation of apoptotic process ALB;PTEN GO:0042493| response to drug CYP2E1;PTEN 30181:[DB06728 DB03206] DB06728|Aniline KLK1;ALB;CYP2E1 DB03206|Duvoglustat MAN1B1;xylA common genes common pathways 30182:[DB06728 DB03389] DB06728|Aniline KLK1;ALB;CYP2E1 DB03389|alpha-D-Xylopyranose LCT common genes common pathways 30183:[DB06728 DB01253] DB06728|Aniline KLK1;ALB;CYP2E1 DB01253|Ergometrine ADRA1A;CYP3A4;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ADRA1A;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30184:[DB06728 DB08048] DB06728|Aniline KLK1;ALB;CYP2E1 DB08048|4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 30185:[DB06728 DB08688] DB06728|Aniline KLK1;ALB;CYP2E1 DB08688|undecan-2-one ACOT13 common genes common pathways 30186:[DB06728 DB01202] DB06728|Aniline KLK1;ALB;CYP2E1 DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCC2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 30187:[DB06728 DB03081] DB06728|Aniline KLK1;ALB;CYP2E1 DB03081|Crc200 (Chiron-Behring) PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30188:[DB06728 DB06880] DB06728|Aniline KLK1;ALB;CYP2E1 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 30189:[DB06728 DB04263] DB06728|Aniline KLK1;ALB;CYP2E1 DB04263|Geneticin ODC1 common genes common pathways 30190:[DB06728 DB00344] DB06728|Aniline KLK1;ALB;CYP2E1 DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A4;SLC6A2;ABCB1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 30191:[DB06728 DB00007] DB06728|Aniline KLK1;ALB;CYP2E1 DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30192:[DB06728 DB08693] DB06728|Aniline KLK1;ALB;CYP2E1 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways GO:0006508| proteolysis CTRB1;KLK1 30193:[DB06728 DB00127] DB06728|Aniline KLK1;ALB;CYP2E1 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0055114| oxidation-reduction process SMOX;XDH;CYP2E1 GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB 30194:[DB06728 DB06420] DB06728|Aniline KLK1;ALB;CYP2E1 DB06420|Annamycin TOP2A common genes common pathways 30195:[DB06728 DB09238] DB06728|Aniline KLK1;ALB;CYP2E1 DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2B6;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2B6;CYP2C9;CYP1A1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP1A1;CYP2C9;CYP2B6;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C9;CYP1A1;CYP2C19;CYP2E1 GO:0042493| response to drug CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP2B6;CYP2C19;CYP2D6;CYP2E1;CYP3A4 30196:[DB06728 DB07382] DB06728|Aniline KLK1;ALB;CYP2E1 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways 30197:[DB06728 DB01712] DB06728|Aniline KLK1;ALB;CYP2E1 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways 30198:[DB06728 DB00301] DB06728|Aniline KLK1;ALB;CYP2E1 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 30199:[DB06728 DB00547] DB06728|Aniline KLK1;ALB;CYP2E1 DB00547|Desoximetasone NR3C1 common genes common pathways 30200:[DB06728 DB04835] DB06728|Aniline KLK1;ALB;CYP2E1 DB04835|Maraviroc CCR5;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30201:[DB06728 DB00868] DB06728|Aniline KLK1;ALB;CYP2E1 DB00868|Benzonatate SCN5A common genes common pathways 30202:[DB06728 DB03844] DB06728|Aniline KLK1;ALB;CYP2E1 DB03844|N-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways 30203:[DB06728 DB07795] DB06728|Aniline KLK1;ALB;CYP2E1 DB07795|Fisetin CDK6 common genes common pathways 30204:[DB06728 DB03096] DB06728|Aniline KLK1;ALB;CYP2E1 DB03096|N-Aminoethylmorpholine CTSD common genes common pathways GO:0006508| proteolysis KLK1;CTSD 30205:[DB06728 DB09103] DB06728|Aniline KLK1;ALB;CYP2E1 DB09103|Ancestim KIT common genes common pathways GO:0043069| negative regulation of programmed cell death ALB;KIT 30206:[DB06728 DB12731] DB06728|Aniline KLK1;ALB;CYP2E1 DB12731|Daporinad NAMPT common genes common pathways 30207:[DB06728 DB00455] DB06728|Aniline KLK1;ALB;CYP2E1 DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2E1 30208:[DB06728 DB07201] DB06728|Aniline KLK1;ALB;CYP2E1 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 30209:[DB06728 DB05077] DB06728|Aniline KLK1;ALB;CYP2E1 DB05077|SLV319 CNR1 common genes common pathways GO:0045471| response to ethanol CNR1;CYP2E1 30210:[DB06728 DB05446] DB06728|Aniline KLK1;ALB;CYP2E1 DB05446|LJP 1082 APOH common genes common pathways GO:0006641| triglyceride metabolic process APOH;CYP2E1 GO:0002576| platelet degranulation ALB;APOH 30211:[DB06728 DB04573] DB06728|Aniline KLK1;ALB;CYP2E1 DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 30212:[DB06728 DB06963] DB06728|Aniline KLK1;ALB;CYP2E1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PLK1 30213:[DB06728 DB00893] DB06728|Aniline KLK1;ALB;CYP2E1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0044267| cellular protein metabolic process TF;ALB GO:0098869| HBB;HBA1;ALB GO:0043687| post-translational protein modification ALB;TF GO:0055114| oxidation-reduction process FTH1;CYP2E1 GO:0002576| platelet degranulation ALB;TF GO:0001895| retina homeostasis ALB;TF GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 30214:[DB06728 DB00128] DB06728|Aniline KLK1;ALB;CYP2E1 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0006508| proteolysis ACY1;KLK1;ASRGL1 GO:0006805| xenobiotic metabolic process CYP2E1;ACY1;ACY3 GO:0045471| response to ethanol GOT2;CYP2E1 GO:0001895| retina homeostasis LYZ;ALB GO:0055114| oxidation-reduction process ASPH;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;ASNS GO:0044267| cellular protein metabolic process LYZ;ALB GO:0017144| drug metabolic process CAD;CYP2E1 30215:[DB06728 DB06321] DB06728|Aniline KLK1;ALB;CYP2E1 DB06321|R-348 JAK3 common genes common pathways 30216:[DB06728 DB02281] DB06728|Aniline KLK1;ALB;CYP2E1 DB02281|Formycin MTAP common genes common pathways 30217:[DB06728 DB13874] DB06728|Aniline KLK1;ALB;CYP2E1 DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process UGT2B15;UGT1A9;CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2C8;CYP2D6;CYP2B6;IDH2;CYP2C9 GO:0042493| response to drug CYP2E1;CYP1A2;UGT1A1;ABCG2;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2B6 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;UGT2B7;UGT1A1;UGT2B15;CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2D6 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1B3;SLC22A8;SLCO1B1 GO:0017144| drug metabolic process CYP2C9;CYP2B6;UGT1A9;UGT1A4;UGT1A1;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CYP1A2;UGT1A3 30218:[DB06728 DB02598] DB06728|Aniline KLK1;ALB;CYP2E1 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0042493| response to drug CYP2E1;PAM GO:0055114| oxidation-reduction process PAM;CYP2E1 30219:[DB06728 DB05209] DB06728|Aniline KLK1;ALB;CYP2E1 DB05209|SYM001 RHD common genes common pathways 30220:[DB06728 DB04437] DB06728|Aniline KLK1;ALB;CYP2E1 DB04437|Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline FABP4 common genes common pathways 30221:[DB06728 DB14639] DB06728|Aniline KLK1;ALB;CYP2E1 DB14639|Boldenone undecylenate AR common genes common pathways 30222:[DB06728 DB00757] DB06728|Aniline KLK1;ALB;CYP2E1 DB00757|Dolasetron HTR3A;CYP3A4;CYP2D6;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;HTR3A GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2D6 30223:[DB06728 DB07231] DB06728|Aniline KLK1;ALB;CYP2E1 DB07231|N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE CTSB common genes common pathways GO:0006508| proteolysis CTSB;KLK1 30224:[DB06728 DB06802] DB06728|Aniline KLK1;ALB;CYP2E1 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| PTGS1;PTGS2;ALB 30225:[DB06728 DB03093] DB06728|Aniline KLK1;ALB;CYP2E1 DB03093|8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 30226:[DB06728 DB07089] DB06728|Aniline KLK1;ALB;CYP2E1 DB07089|N-[amino(imino)methyl]-2-[2-(2-chlorophenyl)-4-(4-propoxyphenyl)-3-thienyl]acetamide BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process BACE1;ALB 30227:[DB06728 DB01764] DB06728|Aniline KLK1;ALB;CYP2E1 DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 30228:[DB06728 DB06144] DB06728|Aniline KLK1;ALB;CYP2E1 DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;HTR2A;HTR2C;DRD2;ADRA1A GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 30229:[DB06728 DB00797] DB06728|Aniline KLK1;ALB;CYP2E1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A 30230:[DB06728 DB00345] DB06728|Aniline KLK1;ALB;CYP2E1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC2;ABCC1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A7;SLC22A11;SLC22A8;SLCO1B1;SLCO1A2;SLCO3A1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1A2;ALB GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 30231:[DB06728 DB02783] DB06728|Aniline KLK1;ALB;CYP2E1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways GO:0045471| response to ethanol CYP2E1;GOT2 30232:[DB06728 DB08046] DB06728|Aniline KLK1;ALB;CYP2E1 DB08046|2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide CA2 common genes common pathways 30233:[DB06728 DB07628] DB06728|Aniline KLK1;ALB;CYP2E1 DB07628|6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one PKM common genes common pathways 30234:[DB06728 DB07895] DB06728|Aniline KLK1;ALB;CYP2E1 DB07895|ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID FNTB;FNTA common genes common pathways 30235:[DB06728 DB06444] DB06728|Aniline KLK1;ALB;CYP2E1 DB06444|Dexanabinol TNF common genes common pathways 30236:[DB06728 DB05595] DB06728|Aniline KLK1;ALB;CYP2E1 DB05595|Farletuzumab FOLR1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FOLR1 30237:[DB06728 DB08174] DB06728|Aniline KLK1;ALB;CYP2E1 DB08174|5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 30238:[DB06728 DB06103] DB06728|Aniline KLK1;ALB;CYP2E1 DB06103|VX-148 IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;IMPDH2;IMPDH1 30239:[DB06728 DB00061] DB06728|Aniline KLK1;ALB;CYP2E1 DB00061|Pegademase bovine GRB2 common genes common pathways 30240:[DB06728 DB07002] DB06728|Aniline KLK1;ALB;CYP2E1 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 30241:[DB06728 DB01113] DB06728|Aniline KLK1;ALB;CYP2E1 DB01113|Papaverine PDE4B;PDE10A common genes common pathways 30242:[DB06728 DB07364] DB06728|Aniline KLK1;ALB;CYP2E1 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways 30243:[DB06728 DB14072] DB06728|Aniline KLK1;ALB;CYP2E1 DB14072|Reversin 121 ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 30244:[DB06728 DB05758] DB06728|Aniline KLK1;ALB;CYP2E1 DB05758|CYT007-TNFQb TNF common genes common pathways 30245:[DB06728 DB07081] DB06728|Aniline KLK1;ALB;CYP2E1 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 30246:[DB06728 DB07683] DB06728|Aniline KLK1;ALB;CYP2E1 DB07683|N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine MMP12 common genes common pathways GO:0006508| proteolysis MMP12;KLK1 30247:[DB06728 DB02681] DB06728|Aniline KLK1;ALB;CYP2E1 DB02681|2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium CKS1B common genes common pathways 30248:[DB06728 DB01136] DB06728|Aniline KLK1;ALB;CYP2E1 DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes CYP2E1 common pathways GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;ADRA1A;ABCB1;UGT1A1;CYP1A1 GO:0043687| post-translational protein modification ALB;HIF1A GO:0055114| oxidation-reduction process PTGS1;XDH;CYP1A2;CYP3A4;CYP2E1;VCAM1;NDUFC2;CYP2D6;CYP1A1;CYP2C9 GO:0002576| platelet degranulation VEGFA;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP1A1;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;HIF1A;VEGFA GO:0018910| benzene metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1;CYP2C9;CYP1A1;CYP2D6 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;UGT1A1;CYP1A1;CYP2C9;CYP2D6 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP1A2;CYP2E1;CYP3A4;PTGS1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6;CYP1A1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0045471| response to ethanol CYP2E1;VCAM1;UGT1A1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 30249:[DB06728 DB00205] DB06728|Aniline KLK1;ALB;CYP2E1 DB00205|Pyrimethamine DHFR;HEXB;CYP2C8;SLC47A1;SLC47A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process DHFR;CYP2C8;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C8 GO:0017144| drug metabolic process CYP2E1;CYP2C8 GO:0044267| cellular protein metabolic process ALB;HEXB GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8 30250:[DB06728 DB00717] DB06728|Aniline KLK1;ALB;CYP2E1 DB00717|Norethisterone PGR;CYP3A4;CYP3A5;CYP3A7;CYP2C19;ALB;SHBG;ABCB1 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2C19;CYP3A5 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP2C19;CYP3A5 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A7;CYP2C19;CYP3A5 30251:[DB06728 DB06495] DB06728|Aniline KLK1;ALB;CYP2E1 DB06495|Onercept TNF common genes common pathways 30252:[DB06728 DB01897] DB06728|Aniline KLK1;ALB;CYP2E1 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways 30253:[DB06728 DB01621] DB06728|Aniline KLK1;ALB;CYP2E1 DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0045471| response to ethanol CYP2E1;DRD2 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0042493| response to drug DRD2;CYP2E1;HTR2A;DRD1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 30254:[DB06728 DB11471] DB06728|Aniline KLK1;ALB;CYP2E1 DB11471|Tilmicosin CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 30255:[DB06728 DB04387] DB06728|Aniline KLK1;ALB;CYP2E1 DB04387|1-Hydroxy-2-Amino-3-Cyclohexylpropane REN common genes common pathways GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug REN;CYP2E1 30256:[DB06728 DB04844] DB06728|Aniline KLK1;ALB;CYP2E1 DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CBR1;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CBR1;CYP2E1 GO:0042493| response to drug CYP2E1;DRD2 30257:[DB06728 DB08067] DB06728|Aniline KLK1;ALB;CYP2E1 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways 30258:[DB06728 DB00425] DB06728|Aniline KLK1;ALB;CYP2E1 DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C9;CYP2E1;CYP1A2 GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6;CYP3A5 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2D6 30259:[DB06728 DB11278] DB06728|Aniline KLK1;ALB;CYP2E1 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 30260:[DB06728 DB02342] DB06728|Aniline KLK1;ALB;CYP2E1 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0006805| xenobiotic metabolic process CYP1B1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1B1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1B1;CYP1A1 GO:0043066| negative regulation of apoptotic process HIF1A;ALB GO:0055114| oxidation-reduction process CYP1B1;CYP1A1;CYP19A1;CYP2E1 GO:0043687| post-translational protein modification ALB;HIF1A GO:0042493| response to drug CYP2E1;CYP1A1;COMT 30261:[DB06728 DB14502] DB06728|Aniline KLK1;ALB;CYP2E1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0042493| response to drug SLC34A1;CYP2E1 GO:0044267| cellular protein metabolic process SLC34A2;ALB;SLC34A1 30262:[DB06728 DB02417] DB06728|Aniline KLK1;ALB;CYP2E1 DB02417|2,4,6-Tribromophenol TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 30263:[DB06728 DB14013] DB06728|Aniline KLK1;ALB;CYP2E1 DB14013|SR-9009 NR1D1;NR1D2 common genes common pathways 30264:[DB06728 DB07410] DB06728|Aniline KLK1;ALB;CYP2E1 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways 30265:[DB06728 DB03542] DB06728|Aniline KLK1;ALB;CYP2E1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 30266:[DB06728 DB11979] DB06728|Aniline KLK1;ALB;CYP2E1 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2D6;CYP2C8;CYP3A5 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A7;CYP2C8;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8 GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP3A4;CYP3A43;CYP3A5;CYP2C8;CYP2D6 GO:0042493| response to drug CYP2E1;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 30267:[DB06728 DB06510] DB06728|Aniline KLK1;ALB;CYP2E1 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP1A2 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP2E1 GO:0042493| response to drug PPARG;UGT1A1;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2;UGT1A3;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2E1;CYP1A2;CYP2C8;UGT1A1 30268:[DB06728 DB00507] DB06728|Aniline KLK1;ALB;CYP2E1 DB00507|Nitazoxanide SLC19A1 common genes common pathways 30269:[DB06728 DB03294] DB06728|Aniline KLK1;ALB;CYP2E1 DB03294|1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide CA2 common genes common pathways 30270:[DB06728 DB07776] DB06728|Aniline KLK1;ALB;CYP2E1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1B1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1B1 GO:0055114| oxidation-reduction process CYP1B1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2E1 30271:[DB06728 DB06689] DB06728|Aniline KLK1;ALB;CYP2E1 DB06689|Ethanolamine oleate F12;CYP2E1 common genes CYP2E1 common pathways GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1 GO:0055114| oxidation-reduction process CYP2E1 GO:0042493| response to drug CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0008202| steroid metabolic process CYP2E1 GO:0017144| drug metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1 GO:0006508| proteolysis KLK1;F12 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 30272:[DB06728 DB00922] DB06728|Aniline KLK1;ALB;CYP2E1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0042493| response to drug PDE3A;CYP2E1;KCNJ11 30273:[DB06728 DB01176] DB06728|Aniline KLK1;ALB;CYP2E1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;SULT1E1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 30274:[DB06728 DB00962] DB06728|Aniline KLK1;ALB;CYP2E1 DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;AOX1;CYP2E1;CYP3A4;CYP3A7 GO:0042493| response to drug CYP2E1;TSPO GO:0017144| drug metabolic process AOX1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;TSPO;CYP2E1;CYP3A7 30275:[DB06728 DB03597] DB06728|Aniline KLK1;ALB;CYP2E1 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways 30276:[DB06728 DB04857] DB06728|Aniline KLK1;ALB;CYP2E1 DB04857|Brasofensine DRD2 common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0042493| response to drug CYP2E1;DRD2 30277:[DB06728 DB02661] DB06728|Aniline KLK1;ALB;CYP2E1 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways 30278:[DB06728 DB01026] DB06728|Aniline KLK1;ALB;CYP2E1 DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP4F12;CYP2E1;CYP2A6;CYP1A2;CYP2D6;CYP2C8;CYP2C19;CYP4F2;CYP2C9;CYP1A1;CYP2B6;UGT1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLCO1B1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2A6;CYP11A1;CYP3A7;CYP51A1;CYP1A2;CYP11B1;UGT2B7;CYP1A1;CYP2C9;NR1I2;CYP2B6;CYP21A2;UGT1A1;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP1B1 GO:0015721| bile acid and bile salt transport ALB;ABCB11;SLCO1B1;SLCO1A2 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP4F12;CYP1A2;CYP2B6;CYP2C9;CYP1A1;CYP2C19;CYP2C8;CYP1B1;CYP4F2 GO:0042493| response to drug CYP2E1;CYP1A2;CYP1A1;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP4F2;CYP1B1;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP21A2;CYP1A1;CYP2C9;CYP19A1;CYP2B6;CYP1A2;CYP26A1;CYP51A1;CYP3A7;CYP11B1;CYP4F12;CYP2E1;CYP3A4;CYP11A1;CYP2A6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP26A1;CYP1A2;CYP3A7;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP1B1;CYP2C9;CYP2B6;NR1I2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1;UGT1A1 30279:[DB06728 DB08229] DB06728|Aniline KLK1;ALB;CYP2E1 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways GO:0006508| proteolysis KLK1;CASP3 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0042493| response to drug CASP3;CYP2E1 30280:[DB06728 DB02079] DB06728|Aniline KLK1;ALB;CYP2E1 DB02079|Aminooxyacetic acid AGXT common genes common pathways 30281:[DB06728 DB05524] DB06728|Aniline KLK1;ALB;CYP2E1 DB05524|Pelitinib EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;ALB 30282:[DB06728 DB00784] DB06728|Aniline KLK1;ALB;CYP2E1 DB00784|Mefenamic acid PTGS2;PTGS1;CYP2C9;CYP2C8;UGT1A9;ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1;CYP2C9;CYP2C8 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A9;CYP2E1 GO:0098869| PTGS1;PTGS2;ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1;UGT1A9;CYP2C9;CYP2C8 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 30283:[DB06728 DB11155] DB06728|Aniline KLK1;ALB;CYP2E1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP2E1;CYP1B1;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP1B1;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1B1;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1B1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 30284:[DB06728 DB00348] DB06728|Aniline KLK1;ALB;CYP2E1 DB00348|Nitisinone HPD common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HPD 30285:[DB06728 DB11644] DB06728|Aniline KLK1;ALB;CYP2E1 DB11644|Tafamidis TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 30286:[DB06728 DB03217] DB06728|Aniline KLK1;ALB;CYP2E1 DB03217|DPI59 SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 30287:[DB06728 DB11751] DB06728|Aniline KLK1;ALB;CYP2E1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8 30288:[DB06728 DB06923] DB06728|Aniline KLK1;ALB;CYP2E1 DB06923|2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30289:[DB06728 DB06840] DB06728|Aniline KLK1;ALB;CYP2E1 DB06840|diethyl [(1R)-1,5-diaminopentyl]boronate PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 30290:[DB06728 DB02076] DB06728|Aniline KLK1;ALB;CYP2E1 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways GO:0055114| oxidation-reduction process PGD;CYP2E1 30291:[DB06728 DB01203] DB06728|Aniline KLK1;ALB;CYP2E1 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 30292:[DB06728 DB08373] DB06728|Aniline KLK1;ALB;CYP2E1 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways GO:0042493| response to drug SCGB1A1;CYP2E1 GO:0010193| response to ozone CYP2E1;SCGB1A1 30293:[DB06728 DB04911] DB06728|Aniline KLK1;ALB;CYP2E1 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 30294:[DB06728 DB01048] DB06728|Aniline KLK1;ALB;CYP2E1 DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2E1 GO:0017144| drug metabolic process UGT1A1;CYP2E1 GO:0055114| oxidation-reduction process ADH6;CYP2E1 GO:0042493| response to drug UGT1A1;CYP2E1 GO:0045471| response to ethanol ADH6;UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 30295:[DB06728 DB01338] DB06728|Aniline KLK1;ALB;CYP2E1 DB01338|Pipecuronium CHRNA2;CHRM2;CHRM3;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 30296:[DB06728 DB04512] DB06728|Aniline KLK1;ALB;CYP2E1 DB04512|2-Isobutyl-3-Methoxypyrazine LCN9 common genes common pathways 30297:[DB06728 DB06228] DB06728|Aniline KLK1;ALB;CYP2E1 DB06228|Rivaroxaban F10;CYP3A4;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP2J2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006508| proteolysis F10;KLK1 GO:0019373| epoxygenase P450 pathway CYP2J2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2J2;CYP3A4;CYP3A5 GO:0042493| response to drug CYP2E1;ABCG2;ABCB1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A4 30298:[DB06728 DB06475] DB06728|Aniline KLK1;ALB;CYP2E1 DB06475|Ruplizumab CD40LG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CD40LG 30299:[DB06728 DB04659] DB06728|Aniline KLK1;ALB;CYP2E1 DB04659|(1S,2S,3R,4S,5S)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 30300:[DB06728 DB04912] DB06728|Aniline KLK1;ALB;CYP2E1 DB04912|Stannsoporfin HMOX1;HMOX2 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP2E1;HMOX2 30301:[DB06728 DB07189] DB06728|Aniline KLK1;ALB;CYP2E1 DB07189|(1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid ADAM17 common genes common pathways GO:0006508| proteolysis ADAM17;KLK1 GO:0042493| response to drug ADAM17;CYP2E1 30302:[DB06728 DB11090] DB06728|Aniline KLK1;ALB;CYP2E1 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 30303:[DB06728 DB03642] DB06728|Aniline KLK1;ALB;CYP2E1 DB03642|Benzofuran-2-Carboxylic Acid {(S)-3-Methyl-1-[3-Oxo-1-(Pyridin-2-Ylsulfonyl)Azepan-4-Ylcarbamoyl]Butyl}Amide CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 30304:[DB06728 DB02685] DB06728|Aniline KLK1;ALB;CYP2E1 DB02685|3-Methylphenylalanine CTSB common genes common pathways GO:0006508| proteolysis KLK1;CTSB 30305:[DB06728 DB01097] DB06728|Aniline KLK1;ALB;CYP2E1 DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process PTK2B;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1;CYP1A2 GO:0042493| response to drug PTK2B;ABCG2;DHODH;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process DHODH;CYP1A2;CYP2E1;CYP2C9 GO:0010243| response to organic nitrogen PTK2B;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2C9;CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0045471| response to ethanol CYP2E1;PTK2B GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2;CYP2C9;AHR 30306:[DB06728 DB00670] DB06728|Aniline KLK1;ALB;CYP2E1 DB00670|Pirenzepine CHRM1 common genes common pathways 30307:[DB06728 DB01169] DB06728|Aniline KLK1;ALB;CYP2E1 DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes ALB common pathways GO:0010243| response to organic nitrogen CCND1;CDKN1A;CYP2E1 GO:0042493| response to drug ABCC2;CDKN1A;ABCB1;HDAC1;CYP1A1;CCND1;CYP2E1;JUN GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1A1;CYP1B1;CYP2E1;CYP3A4;TXNRD1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1B1;CYP1A1 GO:0043066| negative regulation of apoptotic process JUN;AKT1;IKBKB;CDKN1A;ALB;HDAC1 GO:0002576| platelet degranulation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| TXNRD1;ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A1;CYP1B1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;CCND1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 30308:[DB06728 DB04878] DB06728|Aniline KLK1;ALB;CYP2E1 DB04878|Voglibose MGAM common genes common pathways 30309:[DB06728 DB00113] DB06728|Aniline KLK1;ALB;CYP2E1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways GO:0015721| bile acid and bile salt transport CEACAM1;ALB 30310:[DB06728 DB11132] DB06728|Aniline KLK1;ALB;CYP2E1 DB11132|Silicon dioxide MARCO common genes common pathways GO:0006898| receptor-mediated endocytosis MARCO;ALB 30311:[DB06728 DB00831] DB06728|Aniline KLK1;ALB;CYP2E1 DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug ABCB1;ADRA1A;DRD2;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;XDH;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0002576| platelet degranulation ALB;CALM1 GO:0017144| drug metabolic process CYP2E1;CYP1A2;UGT1A4 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 30312:[DB06728 DB00311] DB06728|Aniline KLK1;ALB;CYP2E1 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways GO:0045471| response to ethanol CA3;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB 30313:[DB06728 DB00308] DB06728|Aniline KLK1;ALB;CYP2E1 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0042493| response to drug KCNJ11;CYP2E1 30314:[DB06728 DB02048] DB06728|Aniline KLK1;ALB;CYP2E1 DB02048|1,2,4-Triazole-Carboxamidine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 30315:[DB06728 DB09225] DB06728|Aniline KLK1;ALB;CYP2E1 DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0042493| response to drug SLC6A2;DRD2;CYP1A2;CYP2E1;HTR2A;SLC6A4;DRD1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 30316:[DB06728 DB09237] DB06728|Aniline KLK1;ALB;CYP2E1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;NOS3;NOS2 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 30317:[DB06728 DB06869] DB06728|Aniline KLK1;ALB;CYP2E1 DB06869|1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 30318:[DB06728 DB04368] DB06728|Aniline KLK1;ALB;CYP2E1 DB04368|Bb-3497 def;PDF common genes common pathways 30319:[DB06728 DB03273] DB06728|Aniline KLK1;ALB;CYP2E1 DB03273|3'-Oxo-Adenosine AHCY common genes common pathways 30320:[DB06728 DB04214] DB06728|Aniline KLK1;ALB;CYP2E1 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 30321:[DB06728 DB03078] DB06728|Aniline KLK1;ALB;CYP2E1 DB03078|PASBN SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process SRC;ALB 30322:[DB06728 DB05382] DB06728|Aniline KLK1;ALB;CYP2E1 DB05382|Iodine MT-ND5 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MT-ND5 GO:0010243| response to organic nitrogen MT-ND5;CYP2E1 30323:[DB06728 DB06762] DB06728|Aniline KLK1;ALB;CYP2E1 DB06762|Pinacidil CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 30324:[DB06728 DB02490] DB06728|Aniline KLK1;ALB;CYP2E1 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 30325:[DB06728 DB02106] DB06728|Aniline KLK1;ALB;CYP2E1 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways 30326:[DB06728 DB08011] DB06728|Aniline KLK1;ALB;CYP2E1 DB08011|(3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways 30327:[DB06728 DB02723] DB06728|Aniline KLK1;ALB;CYP2E1 DB02723|4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-Amide F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 30328:[DB06728 DB07702] DB06728|Aniline KLK1;ALB;CYP2E1 DB07702|17alpha-Estriol NCOA5;ESR2 common genes common pathways 30329:[DB06728 DB03539] DB06728|Aniline KLK1;ALB;CYP2E1 DB03539|2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose CHIT1 common genes common pathways 30330:[DB06728 DB00570] DB06728|Aniline KLK1;ALB;CYP2E1 DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;ALB GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;JUN;ABCC6;ABCC1;ABCC2;ABCB1 GO:0043066| negative regulation of apoptotic process ALB;JUN GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 30331:[DB06728 DB02730] DB06728|Aniline KLK1;ALB;CYP2E1 DB02730|4-Methylthio-Alpha-D-Mannose AMY2B common genes common pathways 30332:[DB06728 DB04348] DB06728|Aniline KLK1;ALB;CYP2E1 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;SLCO1B3;NR1H4;SLCO1A2;SLCO2B1;ALB;SLC51B;SLC10A2;SLC10A1;FABP6;SLC51A;SLCO1C1;ABCC3 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1C1;SLC22A6;SLCO4A1;SLC22A8;SLCO1B1;SLCO1B3;SLCO1A2;SLCO3A1 GO:0055114| oxidation-reduction process ABCC4;CYP2E1 GO:0042493| response to drug ABCC1;ABCG2;ABCC2;ABCB1;CYP2E1;ABCC4 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0043066| negative regulation of apoptotic process NR1H4;ALB 30333:[DB06728 DB00463] DB06728|Aniline KLK1;ALB;CYP2E1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 30334:[DB06728 DB04771] DB06728|Aniline KLK1;ALB;CYP2E1 DB04771|1-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 30335:[DB06728 DB00680] DB06728|Aniline KLK1;ALB;CYP2E1 DB00680|Moricizine SCN5A common genes common pathways 30336:[DB06728 DB08035] DB06728|Aniline KLK1;ALB;CYP2E1 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways 30337:[DB06728 DB03338] DB06728|Aniline KLK1;ALB;CYP2E1 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PPARD 30338:[DB06728 DB00579] DB06728|Aniline KLK1;ALB;CYP2E1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0042493| response to drug SLC6A3;SLC6A2;SLC6A4;CYP2E1 30339:[DB06728 DB07354] DB06728|Aniline KLK1;ALB;CYP2E1 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 30340:[DB06728 DB04895] DB06728|Aniline KLK1;ALB;CYP2E1 DB04895|Pegaptanib NRP1 common genes common pathways 30341:[DB06728 DB14581] DB06728|Aniline KLK1;ALB;CYP2E1 DB14581|CPI-1205 EZH2 common genes common pathways 30342:[DB06728 DB14499] DB06728|Aniline KLK1;ALB;CYP2E1 DB14499|Potassium sulfate ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 30343:[DB06728 DB00678] DB06728|Aniline KLK1;ALB;CYP2E1 DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes ALB common pathways GO:0042493| response to drug CYP2E1;SLC22A12;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2C9;UGT1A1;UGT1A3;CYP2E1;CYP3A4;UGT1A10 GO:0043252| sodium-independent organic anion transport SLC22A12;ALB;SLC22A6 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C8;CYP2C19;UGT2B17;CYP2C9;UGT1A1;UGT2B7;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 30344:[DB06728 DB06695] DB06728|Aniline KLK1;ALB;CYP2E1 DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;UGT1A9 GO:0008202| steroid metabolic process UGT2B15;UGT2B7;CYP2E1 GO:0044267| cellular protein metabolic process ALB;F2 GO:0055114| oxidation-reduction process NQO2;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 GO:0006805| xenobiotic metabolic process UGT1A9;UGT2B15;NQO2;CES2;CYP2E1;CES1 GO:0006508| proteolysis KLK1;F2 30345:[DB06728 DB14538] DB06728|Aniline KLK1;ALB;CYP2E1 DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process ANXA1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP11B2;CYP11B1;CYP3A7;CYP2C8;HSD3B1;CYP3A5;HSD11B2 GO:0042493| response to drug ANXA1;ABCG2;HSD11B2;ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP11B1;CYP11B2;CYP3A7;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP2C8;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 30346:[DB06728 DB04661] DB06728|Aniline KLK1;ALB;CYP2E1 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways 30347:[DB06728 DB06283] DB06728|Aniline KLK1;ALB;CYP2E1 DB06283|Ziconotide CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 30348:[DB06728 DB02343] DB06728|Aniline KLK1;ALB;CYP2E1 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways 30349:[DB06728 DB06990] DB06728|Aniline KLK1;ALB;CYP2E1 DB06990|4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;ALB 30350:[DB06728 DB08819] DB06728|Aniline KLK1;ALB;CYP2E1 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;PTGFR;ALB GO:0098869| ALB;PTGS2 30351:[DB06728 DB01384] DB06728|Aniline KLK1;ALB;CYP2E1 DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 30352:[DB06728 DB00627] DB06728|Aniline KLK1;ALB;CYP2E1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB GO:0010243| response to organic nitrogen CYP2E1;NNMT GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0042493| response to drug CYP2E1;NNMT GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 30353:[DB06728 DB00050] DB06728|Aniline KLK1;ALB;CYP2E1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways 30354:[DB06728 DB00401] DB06728|Aniline KLK1;ALB;CYP2E1 DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A7;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 30355:[DB06728 DB06732] DB06728|Aniline KLK1;ALB;CYP2E1 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP1B1;AHR GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP1B1 GO:0055114| oxidation-reduction process CYP1B1;CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP1B1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 30356:[DB06728 DB00341] DB06728|Aniline KLK1;ALB;CYP2E1 DB00341|Cetirizine HRH1 common genes common pathways 30357:[DB06728 DB01054] DB06728|Aniline KLK1;ALB;CYP2E1 DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP2E1;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 30358:[DB06728 DB05983] DB06728|Aniline KLK1;ALB;CYP2E1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;NFKBIA 30359:[DB06728 DB09336] DB06728|Aniline KLK1;ALB;CYP2E1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways 30360:[DB06728 DB09532] DB06728|Aniline KLK1;ALB;CYP2E1 DB09532|Secretin human SCTR common genes common pathways 30361:[DB06728 DB04100] DB06728|Aniline KLK1;ALB;CYP2E1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC2 30362:[DB06728 DB03041] DB06728|Aniline KLK1;ALB;CYP2E1 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 30363:[DB06728 DB03556] DB06728|Aniline KLK1;ALB;CYP2E1 DB03556|2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 CBR1;CBR1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CBR1 GO:0055114| oxidation-reduction process CYP2E1;CBR1 30364:[DB06728 DB04151] DB06728|Aniline KLK1;ALB;CYP2E1 DB04151|4-Methyl-Histidine ACTA1 common genes common pathways 30365:[DB06728 DB07549] DB06728|Aniline KLK1;ALB;CYP2E1 DB07549|2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 30366:[DB06728 DB00126] DB06728|Aniline KLK1;ALB;CYP2E1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0055114| oxidation-reduction process OGFOD1;P3H1;P4HA1;EGLN2;EGLN1;BBOX1;EGLN3;PAM;OGFOD2;PHYH;P4HTM;PLOD3;DBH;ALKBH2;KDM5D;P3H2;PLOD1;P3H3;PLOD2;ALKBH3;TMLHE;CYP2E1 GO:0042493| response to drug CYP2E1;PAM 30367:[DB06728 DB01274] DB06728|Aniline KLK1;ALB;CYP2E1 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process CYP2A6;CYP2E1;CYP2C19;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP2A6 30368:[DB06728 DB03442] DB06728|Aniline KLK1;ALB;CYP2E1 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways 30369:[DB06728 DB09413] DB06728|Aniline KLK1;ALB;CYP2E1 DB09413|Monopotassium phosphate ALPI common genes common pathways 30370:[DB06728 DB06360] DB06728|Aniline KLK1;ALB;CYP2E1 DB06360|Lucatumumab CD40 common genes common pathways 30371:[DB06728 DB07122] DB06728|Aniline KLK1;ALB;CYP2E1 DB07122|1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 30372:[DB06728 DB03581] DB06728|Aniline KLK1;ALB;CYP2E1 DB03581|Glucose-6-Phosphate glmS;GPI;SLCO2A1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO2A1;ALB 30373:[DB06728 DB00035] DB06728|Aniline KLK1;ALB;CYP2E1 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0098869| PTGS2;PTGS1;ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 30374:[DB06728 DB02745] DB06728|Aniline KLK1;ALB;CYP2E1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 30375:[DB06728 DB04059] DB06728|Aniline KLK1;ALB;CYP2E1 DB04059|8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 30376:[DB06728 DB11660] DB06728|Aniline KLK1;ALB;CYP2E1 DB11660|Latanoprostene Bunod PTGFR;SLCO2B1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGFR GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1 30377:[DB06728 DB00669] DB06728|Aniline KLK1;ALB;CYP2E1 DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1A2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1A2 GO:0055114| oxidation-reduction process MAOA;CYP2E1 GO:0042493| response to drug CYP2E1;ABCG2;HTR1B;ABCB1 GO:0045471| response to ethanol HTR1B;CYP2E1 30378:[DB06728 DB09217] DB06728|Aniline KLK1;ALB;CYP2E1 DB09217|Firocoxib PTGS2 common genes common pathways GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 30379:[DB06728 DB00430] DB06728|Aniline KLK1;ALB;CYP2E1 DB00430|Cefpiramide mrcA;mrcA;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 30380:[DB06728 DB05017] DB06728|Aniline KLK1;ALB;CYP2E1 DB05017|YSIL6 TNF;IL6 common genes common pathways GO:0043066| negative regulation of apoptotic process IL6;ALB GO:0043687| post-translational protein modification IL6;ALB GO:0044267| cellular protein metabolic process ALB;IL6 30381:[DB06728 DB03506] DB06728|Aniline KLK1;ALB;CYP2E1 DB03506|9-Deazaadenine APRT common genes common pathways 30382:[DB06728 DB03455] DB06728|Aniline KLK1;ALB;CYP2E1 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways GO:0045471| response to ethanol CYP2E1;IL2 GO:0043066| negative regulation of apoptotic process ALB;IL2 30383:[DB06728 DB12119] DB06728|Aniline KLK1;ALB;CYP2E1 DB12119|Gevokizumab IL1B common genes common pathways 30384:[DB06728 DB07617] DB06728|Aniline KLK1;ALB;CYP2E1 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2A6 GO:0017144| drug metabolic process CYP2E1;CYP2A6 GO:0055114| oxidation-reduction process CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1 30385:[DB06728 DB13751] DB06728|Aniline KLK1;ALB;CYP2E1 DB13751|Glycyrrhizic acid HSD11B1;TNF;CASP3;NFKB2;NFKB1;LPL;AKR1C4;AKR1C3;AKR1C2;ALB;ABCB11 common genes ALB common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1;AKR1C3;AKR1C2;AKR1C4 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation AKR1C3;ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport AKR1C4;ALB;ABCB11 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process NFKB1;CASP3;ALB GO:0042493| response to drug CYP2E1;CASP3;LPL GO:0055114| oxidation-reduction process AKR1C2;AKR1C4;HSD11B1;CYP2E1;AKR1C3 GO:0043687| post-translational protein modification ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006641| triglyceride metabolic process CYP2E1;LPL GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006508| proteolysis KLK1;CASP3 30386:[DB06728 DB06636] DB06728|Aniline KLK1;ALB;CYP2E1 DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 30387:[DB06728 DB03711] DB06728|Aniline KLK1;ALB;CYP2E1 DB03711|6-Hydroxy-6-Methyl-Heptan-3-One LCN9 common genes common pathways 30388:[DB06728 DB04793] DB06728|Aniline KLK1;ALB;CYP2E1 DB04793|1,4:3,6-Dianhydro-2-O-(3-carbamimidoylphenyl)-5-O-(4-carbamimidoylphenyl)-D-glucitol PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30389:[DB06728 DB00081] DB06728|Aniline KLK1;ALB;CYP2E1 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis FCGR1A;ALB;FCGR2B GO:0006508| proteolysis C1R;C1QB;C1QA;KLK1;C1QC 30390:[DB06728 DB02587] DB06728|Aniline KLK1;ALB;CYP2E1 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;GNAS;CYP2E1 30391:[DB06728 DB08049] DB06728|Aniline KLK1;ALB;CYP2E1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0042493| response to drug COMT;CYP2E1 30392:[DB06728 DB11198] DB06728|Aniline KLK1;ALB;CYP2E1 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 30393:[DB06728 DB03040] DB06728|Aniline KLK1;ALB;CYP2E1 DB03040|Nitrilotriacetic Acid LTF common genes common pathways GO:0044267| cellular protein metabolic process LTF;ALB GO:0043066| negative regulation of apoptotic process LTF;ALB GO:0001895| retina homeostasis LTF;ALB GO:0006508| proteolysis LTF;KLK1 30394:[DB06728 DB00545] DB06728|Aniline KLK1;ALB;CYP2E1 DB00545|Pyridostigmine ACHE;BCHE;ALB;CYP3A4 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;BCHE GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 30395:[DB06728 DB01330] DB06728|Aniline KLK1;ALB;CYP2E1 DB01330|Cefotetan ALB common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 30396:[DB06728 DB00490] DB06728|Aniline KLK1;ALB;CYP2E1 DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5;CYP2D6 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0042493| response to drug ABCB1;DRD2;CYP2E1 30397:[DB06728 DB06549] DB06728|Aniline KLK1;ALB;CYP2E1 DB06549|Labradimil BDKRB2 common genes common pathways 30398:[DB06728 DB12474] DB06728|Aniline KLK1;ALB;CYP2E1 DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2C19;CYP2C9;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4 30399:[DB06728 DB01043] DB06728|Aniline KLK1;ALB;CYP2E1 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0042493| response to drug CYP2E1;GRIN2A;DRD2 GO:0055114| oxidation-reduction process CYP2B6;CYP2C19;CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP2B6;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP2A6;CYP2C19;CYP2B6 GO:0008202| steroid metabolic process CYP2B6;CYP2C19;CYP2A6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0045471| response to ethanol GRIN2A;CYP2E1;GRIN2B;GRIN1;HTR3A;DRD2;GRIN3A 30400:[DB06728 DB09472] DB06728|Aniline KLK1;ALB;CYP2E1 DB09472|Sodium sulfate CA2;CA1 common genes common pathways 30401:[DB06728 DB09194] DB06728|Aniline KLK1;ALB;CYP2E1 DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2;SLC6A3 GO:0042493| response to drug SLC6A2;SLC6A3;HTR2C;DRD2;ADRA1A;HTR2A;CYP2E1;SLC6A4 30402:[DB06728 DB00968] DB06728|Aniline KLK1;ALB;CYP2E1 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0042493| response to drug CYP2E1;COMT 30403:[DB06728 DB12163] DB06728|Aniline KLK1;ALB;CYP2E1 DB12163|Sarpogrelate HTR2C;HTR2A common genes common pathways GO:0042493| response to drug HTR2C;CYP2E1;HTR2A 30404:[DB06728 DB00910] DB06728|Aniline KLK1;ALB;CYP2E1 DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP24A1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;UGT1A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 30405:[DB06728 DB02405] DB06728|Aniline KLK1;ALB;CYP2E1 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways 30406:[DB06728 DB01711] DB06728|Aniline KLK1;ALB;CYP2E1 DB01711|2,3,4,5,6-Pentafluorobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;CYP2E1 30407:[DB06728 DB07901] DB06728|Aniline KLK1;ALB;CYP2E1 DB07901|5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE METAP1 common genes common pathways GO:0006508| proteolysis METAP1;KLK1 30408:[DB06728 DB01620] DB06728|Aniline KLK1;ALB;CYP2E1 DB01620|Pheniramine HRH1;NR1I3 common genes common pathways 30409:[DB06728 DB08952] DB06728|Aniline KLK1;ALB;CYP2E1 DB08952|Indenolol CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 30410:[DB06728 DB03637] DB06728|Aniline KLK1;ALB;CYP2E1 DB03637|Guanidine-3-Propanol PRSS3 common genes common pathways GO:0006508| proteolysis KLK1;PRSS3 30411:[DB06728 DB02010] DB06728|Aniline KLK1;ALB;CYP2E1 DB02010|Staurosporine LCK;PIM1;ITK;SYK;MAPKAPK2;GSK3B;CSK;CDK2;PIK3CG;PDPK1;PRKCQ;ZAP70;CHRM1;ABCB1 common genes common pathways GO:0043066| negative regulation of apoptotic process GSK3B;PIM1;ALB GO:0042493| response to drug CYP2E1;ABCB1;LCK 30412:[DB06728 DB09035] DB06728|Aniline KLK1;ALB;CYP2E1 DB09035|Nivolumab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PDCD1;ALB 30413:[DB06728 DB03028] DB06728|Aniline KLK1;ALB;CYP2E1 DB03028|1h-Benoximidazole-2-Carboxylic Acid CTSD common genes common pathways GO:0006508| proteolysis KLK1;CTSD 30414:[DB06728 DB12159] DB06728|Aniline KLK1;ALB;CYP2E1 DB12159|Dupilumab IL4R common genes common pathways 30415:[DB06728 DB08770] DB06728|Aniline KLK1;ALB;CYP2E1 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0042493| response to drug ADORA2A;CYP2E1 30416:[DB06728 DB01107] DB06728|Aniline KLK1;ALB;CYP2E1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 30417:[DB06728 DB02900] DB06728|Aniline KLK1;ALB;CYP2E1 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways GO:0006898| receptor-mediated endocytosis IGF2R;ALB;M6PR 30418:[DB06728 DB01076] DB06728|Aniline KLK1;ALB;CYP2E1 DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;AHR;CYP3A4;CYP2E1;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C19;CYP2D6 GO:0045471| response to ethanol UGT1A1;CYP2E1;HMGCR GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1A2;SLCO1B3;SLCO1B1;ABCB11 GO:0017144| drug metabolic process CYP2C9;CYP2B6;UGT1A1;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4;UGT1A3 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;UGT1A1;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP3A4;CYP2E1;CYP3A7;HMGCR;UGT2B7 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1A2;SLCO1B1;SLCO1B3 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0042493| response to drug ABCC1;UGT1A1;ABCC2;ABCB1;CYP2E1;ABCC4 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP3A5;HMGCR;CYP3A7;CYP3A4;CYP2E1;ABCC4 GO:0043066| negative regulation of apoptotic process ALB;HMGCR GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8;CYP2B6;CYP2C9 GO:0002576| platelet degranulation ALB;ABCC4 30419:[DB06728 DB09073] DB06728|Aniline KLK1;ALB;CYP2E1 DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 30420:[DB06728 DB08816] DB06728|Aniline KLK1;ALB;CYP2E1 DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0042493| response to drug CYP2E1;ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6 30421:[DB06728 DB07498] DB06728|Aniline KLK1;ALB;CYP2E1 DB07498|4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 30422:[DB06728 DB00424] DB06728|Aniline KLK1;ALB;CYP2E1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 30423:[DB06728 DB01946] DB06728|Aniline KLK1;ALB;CYP2E1 DB01946|3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione PDPK1;DMPK common genes common pathways 30424:[DB06728 DB09535] DB06728|Aniline KLK1;ALB;CYP2E1 DB09535|Octocrylene ESR1;ESR2 common genes common pathways 30425:[DB06728 DB01771] DB06728|Aniline KLK1;ALB;CYP2E1 DB01771|CRA_10991 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30426:[DB06728 DB04021] DB06728|Aniline KLK1;ALB;CYP2E1 DB04021|MF268 ACHE common genes common pathways 30427:[DB06728 DB09045] DB06728|Aniline KLK1;ALB;CYP2E1 DB09045|Dulaglutide GLP1R common genes common pathways 30428:[DB06728 DB04505] DB06728|Aniline KLK1;ALB;CYP2E1 DB04505|8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 30429:[DB06728 DB07556] DB06728|Aniline KLK1;ALB;CYP2E1 DB07556|N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL](3-PICOLYL)AMINO]-3-METHYLBUTANAMIDE HYDROCHLORIDE MMP12;MMP1 common genes common pathways GO:0044267| cellular protein metabolic process MMP1;ALB GO:0006508| proteolysis KLK1;MMP12;MMP1 30430:[DB06728 DB07113] DB06728|Aniline KLK1;ALB;CYP2E1 DB07113|(2S)-6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2-(3,5-DIFLUOROPHENYL)-4-(3-METHOXYPROPYL)-2H-1,4-BENZOXAZIN-3(4H)-ONE REN common genes common pathways GO:0042493| response to drug REN;CYP2E1 GO:0006508| proteolysis REN;KLK1 30431:[DB06728 DB00706] DB06728|Aniline KLK1;ALB;CYP2E1 DB00706|Tamsulosin ADRA1A;ADRA1D;ADRA1B;CYP3A4;CYP2D6;ORM1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0002576| platelet degranulation ORM1;ALB GO:0042493| response to drug ADRA1A;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 30432:[DB06728 DB06307] DB06728|Aniline KLK1;ALB;CYP2E1 DB06307|Apoptone BCL2 common genes common pathways GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0042493| response to drug BCL2;CYP2E1 30433:[DB06728 DB01418] DB06728|Aniline KLK1;ALB;CYP2E1 DB01418|Acenocoumarol VKORC1;CYP2C9;CYP1A2;CYP2C19;CYP3A4;ALB;ORM1 common genes ALB common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP1A2;VKORC1;CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1;CYP1A2 GO:0002576| platelet degranulation ALB;ORM1 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;VKORC1;CYP2C9;CYP2C19 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19;CYP2C9 30434:[DB06728 DB09105] DB06728|Aniline KLK1;ALB;CYP2E1 DB09105|Asfotase Alfa S1PR1 common genes common pathways 30435:[DB06728 DB09299] DB06728|Aniline KLK1;ALB;CYP2E1 DB09299|Tenofovir alafenamide pol;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 30436:[DB06728 DB12130] DB06728|Aniline KLK1;ALB;CYP2E1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP2E1;CYP3A5;CYP2C8;CYP2C19;CYP2B6 GO:0008202| steroid metabolic process CYP2E1;CYP2B6;CYP3A5;CYP2C19;CYP2C8 GO:0017144| drug metabolic process UGT1A3;CYP2E1;CYP2C19;CYP2C8;CYP2B6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8;CYP2C19;CYP3A5;CYP2B6 30437:[DB06728 DB09039] DB06728|Aniline KLK1;ALB;CYP2E1 DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 30438:[DB06728 DB06325] DB06728|Aniline KLK1;ALB;CYP2E1 DB06325|Pegpleranib PDGFB common genes common pathways GO:0002576| platelet degranulation ALB;PDGFB 30439:[DB06728 DB07286] DB06728|Aniline KLK1;ALB;CYP2E1 DB07286|BMS-564929 AR common genes common pathways 30440:[DB06728 DB04620] DB06728|Aniline KLK1;ALB;CYP2E1 DB04620|Cycloleucine GRIN1 common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN1 30441:[DB06728 DB07632] DB06728|Aniline KLK1;ALB;CYP2E1 DB07632|5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide CA2 common genes common pathways 30442:[DB06728 DB01332] DB06728|Aniline KLK1;ALB;CYP2E1 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8 30443:[DB06728 DB07344] DB06728|Aniline KLK1;ALB;CYP2E1 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways 30444:[DB06728 DB06016] DB06728|Aniline KLK1;ALB;CYP2E1 DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug HTR2A;CYP2E1;HTR2B;DRD2;DRD3 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 30445:[DB06728 DB03923] DB06728|Aniline KLK1;ALB;CYP2E1 DB03923|Feruloyl Coenzyme A COMTD1 common genes common pathways 30446:[DB06728 DB09289] DB06728|Aniline KLK1;ALB;CYP2E1 DB09289|Tianeptine GRIA1;OPRM1;HTR1A;DRD3;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol DRD3;OPRM1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug DRD3;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 30447:[DB06728 DB06688] DB06728|Aniline KLK1;ALB;CYP2E1 DB06688|Sipuleucel-T ACPP common genes common pathways 30448:[DB06728 DB07394] DB06728|Aniline KLK1;ALB;CYP2E1 DB07394|AUROVERTIN B ATP5B common genes common pathways 30449:[DB06728 DB05192] DB06728|Aniline KLK1;ALB;CYP2E1 DB05192|MB07811 THRB common genes common pathways 30450:[DB06728 DB09341] DB06728|Aniline KLK1;ALB;CYP2E1 DB09341|Dextrose, unspecified form HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1 common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC2A4 30451:[DB06728 DB04519] DB06728|Aniline KLK1;ALB;CYP2E1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A11;SLC22A6;ALB 30452:[DB06728 DB00322] DB06728|Aniline KLK1;ALB;CYP2E1 DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0045471| response to ethanol TYMS;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0042493| response to drug TYMS;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C9 30453:[DB06728 DB03664] DB06728|Aniline KLK1;ALB;CYP2E1 DB03664|UP5 CMPK1 common genes common pathways 30454:[DB06728 DB08088] DB06728|Aniline KLK1;ALB;CYP2E1 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways 30455:[DB06728 DB01216] DB06728|Aniline KLK1;ALB;CYP2E1 DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0009267| cellular response to starvation SRD5A1;ALB GO:0008202| steroid metabolic process CYP3A5;SRD5A1;CYP3A7;AKR1D1;SRD5A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;SRD5A2;SRD5A1 GO:0055114| oxidation-reduction process CYP3A7;AKR1D1;CYP3A4;CYP2E1;SRD5A2;SRD5A1;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 30456:[DB06728 DB08740] DB06728|Aniline KLK1;ALB;CYP2E1 DB08740|CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE CTSD common genes common pathways GO:0006508| proteolysis CTSD;KLK1 30457:[DB06728 DB06730] DB06728|Aniline KLK1;ALB;CYP2E1 DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4 30458:[DB06728 DB00191] DB06728|Aniline KLK1;ALB;CYP2E1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0045471| response to ethanol MAOB;SLC6A3;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process MAOB;MAOA;CYP1A2;CYP2E1 GO:0042493| response to drug SLC6A3;SLC6A2;MAOB;SLC6A4;CYP2E1;CYP1A2 30459:[DB06728 DB07934] DB06728|Aniline KLK1;ALB;CYP2E1 DB07934|[[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 30460:[DB06728 DB04688] DB06728|Aniline KLK1;ALB;CYP2E1 DB04688|Methylecgonine IGHG2;IGKC common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;IGKC GO:0001895| retina homeostasis ALB;IGKC GO:0006508| proteolysis IGHG2;IGKC;KLK1 30461:[DB06728 DB06650] DB06728|Aniline KLK1;ALB;CYP2E1 DB06650|Ofatumumab MS4A1 common genes common pathways 30462:[DB06728 DB00371] DB06728|Aniline KLK1;ALB;CYP2E1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes CYP2E1 common pathways GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C19 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1 GO:0042493| response to drug GABRG3;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1 GO:0010193| response to ozone CYP2E1 30463:[DB06728 DB03456] DB06728|Aniline KLK1;ALB;CYP2E1 DB03456|N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 30464:[DB06728 DB07310] DB06728|Aniline KLK1;ALB;CYP2E1 DB07310|(5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(trifluoromethyl)-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 GO:0008202| steroid metabolic process HSD11B1;CYP2E1 30465:[DB06728 DB06684] DB06728|Aniline KLK1;ALB;CYP2E1 DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0042493| response to drug SLC6A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C18;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C18;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4;CYP2C18 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 30466:[DB06728 DB04409] DB06728|Aniline KLK1;ALB;CYP2E1 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways 30467:[DB06728 DB02509] DB06728|Aniline KLK1;ALB;CYP2E1 DB02509|Farnesol MAOB;NR1H4;MAOB common genes common pathways GO:0045471| response to ethanol CYP2E1;MAOB GO:0043066| negative regulation of apoptotic process NR1H4;ALB GO:0055114| oxidation-reduction process CYP2E1;MAOB GO:0042493| response to drug MAOB;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;NR1H4 30468:[DB06728 DB08560] DB06728|Aniline KLK1;ALB;CYP2E1 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 30469:[DB06728 DB07917] DB06728|Aniline KLK1;ALB;CYP2E1 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways 30470:[DB06728 DB03384] DB06728|Aniline KLK1;ALB;CYP2E1 DB03384|Fica CASP7 common genes common pathways GO:0006508| proteolysis CASP7;KLK1 30471:[DB06728 DB07630] DB06728|Aniline KLK1;ALB;CYP2E1 DB07630|N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 30472:[DB06728 DB00283] DB06728|Aniline KLK1;ALB;CYP2E1 DB00283|Clemastine HRH1;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 30473:[DB06728 DB00530] DB06728|Aniline KLK1;ALB;CYP2E1 DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes ALB common pathways GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;UGT1A1;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1B1;CYP2C8;CYP2D6;CYP3A5;UGT1A1;NR1I2;CYP1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1 GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1 GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB;ORM1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8;CYP1A1;CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;UGT1A1;CYP1A1;ABCB1;ABCG2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP1A1;CYP1B1;CYP2D6;CYP2C8;CYP3A5 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;NR1I2;CYP1B1;CYP2C8;CYP2D6;CYP3A5 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;UGT1A1;CYP1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol CYP2E1;UGT1A1 30474:[DB06728 DB00931] DB06728|Aniline KLK1;ALB;CYP2E1 DB00931|Metacycline ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 30475:[DB06728 DB05233] DB06728|Aniline KLK1;ALB;CYP2E1 DB05233|AP1081 ESR1 common genes common pathways 30476:[DB06728 DB00903] DB06728|Aniline KLK1;ALB;CYP2E1 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0098869| GSTP1;ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043066| negative regulation of apoptotic process LEF1;ALB;GSTP1 GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;ATP1A1 30477:[DB06728 DB07789] DB06728|Aniline KLK1;ALB;CYP2E1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PLK1 30478:[DB06728 DB06945] DB06728|Aniline KLK1;ALB;CYP2E1 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways GO:0006508| proteolysis KLK1;ADAMTS5 30479:[DB06728 DB02855] DB06728|Aniline KLK1;ALB;CYP2E1 DB02855|N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline CTSB common genes common pathways GO:0006508| proteolysis CTSB;KLK1 30480:[DB06728 DB00856] DB06728|Aniline KLK1;ALB;CYP2E1 DB00856|Chlorphenesin CYP2B;CYP19A1;CYP3A4;XDH;PTGS2;BCHE common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0098869| ALB;PTGS2 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0042493| response to drug BCHE;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;XDH;CYP2E1;CYP3A4;CYP19A1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 30481:[DB06728 DB02328] DB06728|Aniline KLK1;ALB;CYP2E1 DB02328|2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid CTH common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CTH 30482:[DB06728 DB04491] DB06728|Aniline KLK1;ALB;CYP2E1 DB04491|Diisopropylphosphono Group CFB;DPP4 common genes common pathways GO:0006508| proteolysis KLK1;CFB;DPP4 30483:[DB06728 DB01089] DB06728|Aniline KLK1;ALB;CYP2E1 DB01089|Deserpidine SLC18A2 common genes common pathways 30484:[DB06728 DB13166] DB06728|Aniline KLK1;ALB;CYP2E1 DB13166|Zofenopril ACE common genes common pathways GO:0006508| proteolysis ACE;KLK1 30485:[DB06728 DB01744] DB06728|Aniline KLK1;ALB;CYP2E1 DB01744|Camphor TRPV1;TRPV3;TRPA1;TRPM8 common genes common pathways GO:0042493| response to drug TRPA1;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;TRPV1 30486:[DB06728 DB07363] DB06728|Aniline KLK1;ALB;CYP2E1 DB07363|THIOPHENE-2,5-DISULFONIC ACID 2-AMIDE-5-(4-METHYL-BENZYLAMIDE) CA2 common genes common pathways 30487:[DB06728 DB01223] DB06728|Aniline KLK1;ALB;CYP2E1 DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes CYP2E1 common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19 GO:0045471| response to ethanol CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;HDAC2;PDE3A GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP2C19 GO:0010243| response to organic nitrogen CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PDE3A;ADORA1;HDAC2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19 GO:0018910| benzene metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP3A4;CYP2E1;CYP1A2 30488:[DB06728 DB00861] DB06728|Aniline KLK1;ALB;CYP2E1 DB00861|Diflunisal PTGS2;PTGS1;UGT1A8;UGT1A9;TTR;ALB;SLC22A6 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process TTR;ALB GO:0098869| ALB;PTGS1;PTGS2 GO:0017144| drug metabolic process UGT1A8;UGT1A9;CYP2E1 GO:0008202| steroid metabolic process UGT1A8;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug CYP2E1;PTGS2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0002576| platelet degranulation ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process UGT1A9;PTGS1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 30489:[DB06728 DB00995] DB06728|Aniline KLK1;ALB;CYP2E1 DB00995|Auranofin PRDX5;IKBKB;ALB common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB;PRDX5 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;PRDX5 GO:0043066| negative regulation of apoptotic process PRDX5;IKBKB;ALB GO:0002576| platelet degranulation ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 30490:[DB06728 DB00108] DB06728|Aniline KLK1;ALB;CYP2E1 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0006508| proteolysis C1R;C1QB;C1QC;C1QA;KLK1 GO:0045471| response to ethanol ICAM1;CYP2E1 GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0042493| response to drug CYP2E1;ICAM1 30491:[DB06728 DB09236] DB06728|Aniline KLK1;ALB;CYP2E1 DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0002576| platelet degranulation ALB;ORM1 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 30492:[DB06728 DB08930] DB06728|Aniline KLK1;ALB;CYP2E1 DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes common pathways GO:0042493| response to drug CYP2E1;UGT1A1;ABCB1;ABCG2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A7;CYP3A43;CYP3A5 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLC22A6 GO:0008202| steroid metabolic process UGT1A1;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;UGT1A3;UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0006805| xenobiotic metabolic process UGT1A9;CYP3A5;CYP3A7;CYP2E1;CYP3A4 30493:[DB06728 DB11858] DB06728|Aniline KLK1;ALB;CYP2E1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways 30494:[DB06728 DB14132] DB06728|Aniline KLK1;ALB;CYP2E1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug ADORA2A;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 30495:[DB06728 DB07165] DB06728|Aniline KLK1;ALB;CYP2E1 DB07165|N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 30496:[DB06728 DB07257] DB06728|Aniline KLK1;ALB;CYP2E1 DB07257|4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione WEE1 common genes common pathways 30497:[DB06728 DB07716] DB06728|Aniline KLK1;ALB;CYP2E1 DB07716|(4Z)-2,8:7,12:11,15:14,18:17,22-PENTAANHYDRO-4,5,6,9,10,13,19,20,21-NONADEOXY-D-ARABINO-D-ALLO-D-ALLO-DOCOSA-4,9,20-TRIENITOL IGKC common genes common pathways GO:0006898| receptor-mediated endocytosis IGKC;ALB GO:0001895| retina homeostasis ALB;IGKC GO:0006508| proteolysis IGKC;KLK1 30498:[DB06728 DB09070] DB06728|Aniline KLK1;ALB;CYP2E1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;SULT1A1 GO:0008202| steroid metabolic process SULT1A1;STS;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;HSD3B2;HSD3B1 GO:0043687| post-translational protein modification ALB;STS 30499:[DB06728 DB04905] DB06728|Aniline KLK1;ALB;CYP2E1 DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP1A1 GO:0017144| drug metabolic process CYP2D6;CYP1A1;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 GO:0042493| response to drug CYP2E1;CYP1A1;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP1A1;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 30500:[DB06728 DB09479] DB06728|Aniline KLK1;ALB;CYP2E1 DB09479|Rubidium Rb-82 FXYD2;ATP1A1;ATP1B1;ATP1B2;ATP1B3;ATP1A4;ATP1A2;ATP1A3 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1;ATP1A3 30501:[DB06728 DB02462] DB06728|Aniline KLK1;ALB;CYP2E1 DB02462|Thiocoumarin NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 30502:[DB06728 DB04509] DB06728|Aniline KLK1;ALB;CYP2E1 DB04509|N-Methylnaloxonium CES1;CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CES1;CYP2E1 30503:[DB06728 DB02395] DB06728|Aniline KLK1;ALB;CYP2E1 DB02395|3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol NQO1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0006805| xenobiotic metabolic process CYP2E1;NQO1 GO:0045471| response to ethanol NQO1;CYP2E1 30504:[DB06728 DB00964] DB06728|Aniline KLK1;ALB;CYP2E1 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 30505:[DB06728 DB00487] DB06728|Aniline KLK1;ALB;CYP2E1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 30506:[DB06728 DB04549] DB06728|Aniline KLK1;ALB;CYP2E1 DB04549|4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide CA2 common genes common pathways 30507:[DB06728 DB02861] DB06728|Aniline KLK1;ALB;CYP2E1 DB02861|4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide CA2 common genes common pathways 30508:[DB06728 DB07154] DB06728|Aniline KLK1;ALB;CYP2E1 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 30509:[DB06728 DB13881] DB06728|Aniline KLK1;ALB;CYP2E1 DB13881|Tisagenlecleucel CD19 common genes common pathways 30510:[DB06728 DB04233] DB06728|Aniline KLK1;ALB;CYP2E1 DB04233|(Hydroxyethyloxy)Tri(Ethyloxy)Octane CLPS;PNLIP;RHO common genes common pathways 30511:[DB06728 DB03703] DB06728|Aniline KLK1;ALB;CYP2E1 DB03703|Cyclohexanol ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;CYP2E1 30512:[DB06728 DB09203] DB06728|Aniline KLK1;ALB;CYP2E1 DB09203|Synephrine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A 30513:[DB06728 DB02744] DB06728|Aniline KLK1;ALB;CYP2E1 DB02744|RPR131247 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 30514:[DB06728 DB13132] DB06728|Aniline KLK1;ALB;CYP2E1 DB13132|Artemisinin CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2B6 GO:0017144| drug metabolic process CYP2E1;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6 GO:0055114| oxidation-reduction process CYP2E1;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2E1 30515:[DB06728 DB04852] DB06728|Aniline KLK1;ALB;CYP2E1 DB04852|Implitapide MTTP common genes common pathways 30516:[DB06728 DB00682] DB06728|Aniline KLK1;ALB;CYP2E1 DB00682|Warfarin VKORC1;NR1I2;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2C8;CYP2C18;CYP1A1;ALB;ORM1 common genes ALB common pathways GO:0002576| platelet degranulation ALB;ORM1 GO:0019373| epoxygenase P450 pathway CYP2C18;CYP2E1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP1A1 GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP1A2;VKORC1;CYP2E1;CYP3A4;CYP2C18;CYP1A1;CYP2C9;CYP2C8;CYP2C19 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP1A2;CYP2E1;CYP1A1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2C8;NR1I2;CYP1A1;CYP2C9 GO:0017144| drug metabolic process VKORC1;CYP1A2;CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP1A1;CYP2C9 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C18;NR1I2;CYP2C9;CYP2C8;CYP2C19 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 30517:[DB06728 DB05920] DB06728|Aniline KLK1;ALB;CYP2E1 DB05920|RTA 744 TOP2A common genes common pathways 30518:[DB06728 DB08163] DB06728|Aniline KLK1;ALB;CYP2E1 DB08163|5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine AMD1 common genes common pathways 30519:[DB06728 DB03894] DB06728|Aniline KLK1;ALB;CYP2E1 DB03894|N-Propargyl-1(S)-Aminoindan MAOB;MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0042493| response to drug CYP2E1;MAOB GO:0055114| oxidation-reduction process CYP2E1;MAOB 30520:[DB06728 DB05938] DB06728|Aniline KLK1;ALB;CYP2E1 DB05938|Edonerpic APP common genes common pathways GO:0044267| cellular protein metabolic process APP;ALB GO:0002576| platelet degranulation APP;ALB GO:0043687| post-translational protein modification ALB;APP 30521:[DB06728 DB12610] DB06728|Aniline KLK1;ALB;CYP2E1 DB12610|Ebselen EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;EPHX2 GO:0006805| xenobiotic metabolic process EPHX2;CYP2E1 30522:[DB06728 DB07063] DB06728|Aniline KLK1;ALB;CYP2E1 DB07063|{3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 30523:[DB06728 DB11397] DB06728|Aniline KLK1;ALB;CYP2E1 DB11397|Dichlorvos TF;BCHE;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis TF;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation TF;ALB GO:0042493| response to drug BCHE;CYP2E1 GO:0043687| post-translational protein modification ALB;TF GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB;TF 30524:[DB06728 DB00600] DB06728|Aniline KLK1;ALB;CYP2E1 DB00600|Monobenzone TYR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;TYR 30525:[DB06728 DB03889] DB06728|Aniline KLK1;ALB;CYP2E1 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 30526:[DB06728 DB01831] DB06728|Aniline KLK1;ALB;CYP2E1 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways 30527:[DB06728 DB01589] DB06728|Aniline KLK1;ALB;CYP2E1 DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2B6;CYP2C19 GO:0042493| response to drug CYP2E1;GABRG3 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2C19 30528:[DB06728 DB14527] DB06728|Aniline KLK1;ALB;CYP2E1 DB14527|Chromic nitrate CYB5A;TF common genes common pathways GO:0001895| retina homeostasis TF;ALB GO:0044267| cellular protein metabolic process ALB;TF GO:0055114| oxidation-reduction process CYB5A;CYP2E1 GO:0043687| post-translational protein modification ALB;TF GO:0002576| platelet degranulation TF;ALB 30529:[DB06728 DB02637] DB06728|Aniline KLK1;ALB;CYP2E1 DB02637|Oxaloacetate Ion CS;mdh;SPR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;SPR 30530:[DB06728 DB08435] DB06728|Aniline KLK1;ALB;CYP2E1 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 30531:[DB06728 DB07580] DB06728|Aniline KLK1;ALB;CYP2E1 DB07580|BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE APCS common genes common pathways GO:0044267| cellular protein metabolic process ALB;APCS 30532:[DB06728 DB00104] DB06728|Aniline KLK1;ALB;CYP2E1 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;MPO GO:0043066| negative regulation of apoptotic process ALB;MPO 30533:[DB06728 DB06410] DB06728|Aniline KLK1;ALB;CYP2E1 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP27A1 30534:[DB06728 DB01064] DB06728|Aniline KLK1;ALB;CYP2E1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0045471| response to ethanol CYP2E1;SOD1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0001895| retina homeostasis SOD1;ALB GO:0043066| negative regulation of apoptotic process PIK3R1;ALB;SOD1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0002576| platelet degranulation SOD1;ALB GO:0055114| oxidation-reduction process SOD1;CYP2E1;CYP1A1 GO:0042493| response to drug SOD1;CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP2E1;CYP1A1 GO:0017144| drug metabolic process CYP2E1;CYP1A1 30535:[DB06728 DB03948] DB06728|Aniline KLK1;ALB;CYP2E1 DB03948|6-Chloropurine Riboside, 5'-Monophosphate IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;IMPDH2;IMPDH1 30536:[DB06728 DB06721] DB06728|Aniline KLK1;ALB;CYP2E1 DB06721|Gimatecan SLCO1B1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 30537:[DB06728 DB04853] DB06728|Aniline KLK1;ALB;CYP2E1 DB04853|Binodenoson ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;CYP2E1 GO:0044267| cellular protein metabolic process ALB;ADORA2A 30538:[DB06728 DB06414] DB06728|Aniline KLK1;ALB;CYP2E1 DB06414|Etravirine CYP3A4;CYP2C9;CYP2C19;ABCB1;ABCB4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1;ABCB4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19;CYP2C9 30539:[DB06728 DB01947] DB06728|Aniline KLK1;ALB;CYP2E1 DB01947|RU78262 SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 30540:[DB06728 DB02515] DB06728|Aniline KLK1;ALB;CYP2E1 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways 30541:[DB06728 DB04336] DB06728|Aniline KLK1;ALB;CYP2E1 DB04336|1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30542:[DB06728 DB03486] DB06728|Aniline KLK1;ALB;CYP2E1 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways 30543:[DB06728 DB07786] DB06728|Aniline KLK1;ALB;CYP2E1 DB07786|1-((1R,2S)-1-{2-[2-(4-CHLOROPHENYL)-1,3-BENZOXAZOL-7-YL]ETHYL}-2-HYDROXYPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ADA;ALB GO:0042493| response to drug CYP2E1;ADA 30544:[DB06728 DB07747] DB06728|Aniline KLK1;ALB;CYP2E1 DB07747|(3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 30545:[DB06728 DB14529] DB06728|Aniline KLK1;ALB;CYP2E1 DB14529|Chromium nicotinate CYB5A;TF common genes common pathways GO:0044267| cellular protein metabolic process ALB;TF GO:0002576| platelet degranulation TF;ALB GO:0055114| oxidation-reduction process CYB5A;CYP2E1 GO:0043687| post-translational protein modification ALB;TF GO:0001895| retina homeostasis ALB;TF 30546:[DB06728 DB01678] DB06728|Aniline KLK1;ALB;CYP2E1 DB01678|RU84687 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug CYP2E1;SRC 30547:[DB06728 DB10772] DB06728|Aniline KLK1;ALB;CYP2E1 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;TGFBR2 GO:0045471| response to ethanol CYP2E1;FGFR2 GO:0044267| cellular protein metabolic process ALB;IL6;CSF2RA GO:0043066| negative regulation of apoptotic process VEGFA;ALB;EGFR;IL6 GO:0002576| platelet degranulation ALB;VEGFA;TGFB1 GO:0043687| post-translational protein modification ALB;IL6 GO:0042493| response to drug TGFBR2;CYP2E1;TGFB1 30548:[DB06728 DB02107] DB06728|Aniline KLK1;ALB;CYP2E1 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 30549:[DB06728 DB08488] DB06728|Aniline KLK1;ALB;CYP2E1 DB08488|4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 30550:[DB06728 DB07087] DB06728|Aniline KLK1;ALB;CYP2E1 DB07087|4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 30551:[DB06728 DB04256] DB06728|Aniline KLK1;ALB;CYP2E1 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways 30552:[DB06728 DB06538] DB06728|Aniline KLK1;ALB;CYP2E1 DB06538|Robalzotan HTR1A common genes common pathways 30553:[DB06728 DB08156] DB06728|Aniline KLK1;ALB;CYP2E1 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways 30554:[DB06728 DB14002] DB06728|Aniline KLK1;ALB;CYP2E1 DB14002|D-alpha-Tocopherol acetate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0008202| steroid metabolic process CYP2E1;NR1I2 GO:0098869| GSTP1;ALB;GSTO1 GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB;NQO1;GCLC;SOD1 GO:0042493| response to drug CYP2E1;SOD1 GO:0055114| oxidation-reduction process ALOX5;HMOX1;GSTO1;CYP2E1;SOD1;NQO1 GO:0001895| retina homeostasis ALB;SOD1 GO:0045471| response to ethanol GSTP1;NQO1;SOD1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;NR1I2;NQO1;GSTP1 30555:[DB06728 DB08190] DB06728|Aniline KLK1;ALB;CYP2E1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways GO:0055114| oxidation-reduction process NQO2;CYP2E1 GO:0006805| xenobiotic metabolic process NQO2;CYP2E1 30556:[DB06728 DB08221] DB06728|Aniline KLK1;ALB;CYP2E1 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways GO:0043066| negative regulation of apoptotic process TEK;ALB 30557:[DB06728 DB09280] DB06728|Aniline KLK1;ALB;CYP2E1 DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP2B6;CYP2C9 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C19;CYP2C8;CYP2C9;CYP2B6 GO:0042493| response to drug CYP2E1;ABCB1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 30558:[DB06728 DB06868] DB06728|Aniline KLK1;ALB;CYP2E1 DB06868|N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 30559:[DB06728 DB00633] DB06728|Aniline KLK1;ALB;CYP2E1 DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes CYP2E1 common pathways GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP1A2 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A1;CYP1A2;CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP1A2;CYP2D6;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP1A1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP2D6;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP1A1 GO:0018910| benzene metabolic process CYP2E1 30560:[DB06728 DB04578] DB06728|Aniline KLK1;ALB;CYP2E1 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 30561:[DB06728 DB01349] DB06728|Aniline KLK1;ALB;CYP2E1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;AGTR2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 30562:[DB06728 DB11774] DB06728|Aniline KLK1;ALB;CYP2E1 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 30563:[DB06728 DB04910] DB06728|Aniline KLK1;ALB;CYP2E1 DB04910|Oxibendazole TUBB4B common genes common pathways 30564:[DB06728 DB08772] DB06728|Aniline KLK1;ALB;CYP2E1 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;AKR1B10;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0008202| steroid metabolic process CYP2E1;AKR1B10 30565:[DB06728 DB00471] DB06728|Aniline KLK1;ALB;CYP2E1 DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways GO:0055114| oxidation-reduction process ALOX5;PTGS1;CYP2A6;CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP2C9;CYP2C8 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP2A6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4;CYP2C9;CYP2C8 GO:0098869| PTGS1;ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;PTGS1;CYP2E1;CYP3A4 30566:[DB06728 DB08222] DB06728|Aniline KLK1;ALB;CYP2E1 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways 30567:[DB06728 DB01587] DB06728|Aniline KLK1;ALB;CYP2E1 DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0042493| response to drug CYP2E1;TSPO;ABCB1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;TSPO GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 30568:[DB06728 DB13500] DB06728|Aniline KLK1;ALB;CYP2E1 DB13500|Otilonium CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 30569:[DB06728 DB02131] DB06728|Aniline KLK1;ALB;CYP2E1 DB02131|N-1-Methylheptylformamide ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1C 30570:[DB06728 DB01951] DB06728|Aniline KLK1;ALB;CYP2E1 DB01951|Gpi-1046 FKBP1A common genes common pathways 30571:[DB06728 DB09154] DB06728|Aniline KLK1;ALB;CYP2E1 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 30572:[DB06728 DB00140] DB06728|Aniline KLK1;ALB;CYP2E1 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0055114| oxidation-reduction process BLVRB;MAOA;MTHFR;CYP2E1 GO:0042493| response to drug MTHFR;CYP2E1 30573:[DB06728 DB01231] DB06728|Aniline KLK1;ALB;CYP2E1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways 30574:[DB06728 DB00710] DB06728|Aniline KLK1;ALB;CYP2E1 DB00710|Ibandronate FDPS common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 30575:[DB06728 DB00144] DB06728|Aniline KLK1;ALB;CYP2E1 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;SCARB1 GO:0034375| high-density lipoprotein particle remodeling SCARB1;ALB 30576:[DB06728 DB06954] DB06728|Aniline KLK1;ALB;CYP2E1 DB06954|2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate CA2 common genes common pathways 30577:[DB06728 DB00511] DB06728|Aniline KLK1;ALB;CYP2E1 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 30578:[DB06728 DB08220] DB06728|Aniline KLK1;ALB;CYP2E1 DB08220|(8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid NCOA1;NR1H4 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NR1H4;NCOA1 GO:0043066| negative regulation of apoptotic process ALB;NR1H4 30579:[DB06728 DB00917] DB06728|Aniline KLK1;ALB;CYP2E1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP11A1 GO:0043252| sodium-independent organic anion transport SLC22A6;SLCO2A1;SLCO1C1;ALB;SLCO2B1;SLC22A8;SLCO1B1;SLCO3A1;SLCO1A2;SLCO4A1;SLC22A7;SLC22A11 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;SLCO1C1;SLC51A;SLC51B;ALB;SLCO2B1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0055114| oxidation-reduction process ABCC4;CYP11A1;CYP2E1;CYP19A1 GO:0042493| response to drug ABCC4;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 30580:[DB06728 DB01583] DB06728|Aniline KLK1;ALB;CYP2E1 DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0042493| response to drug ABCB1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 GO:0098869| ALB GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO4C1;SLCO1C1;SLC16A2;SLCO4A1;SLC22A8;SLCO1B1;SLCO1B3;SLCO1A2 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;SLCO1A2;SLCO1C1;ALB;SLC10A1 GO:0044267| cellular protein metabolic process ALB;TTR 30581:[DB06728 DB03963] DB06728|Aniline KLK1;ALB;CYP2E1 DB03963|S-(Dimethylarsenic)Cysteine TLR2;NOS3;COPG1;XRCC4;msrA common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 30582:[DB06728 DB00331] DB06728|Aniline KLK1;ALB;CYP2E1 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways 30583:[DB06728 DB08353] DB06728|Aniline KLK1;ALB;CYP2E1 DB08353|2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 30584:[DB06728 DB03292] DB06728|Aniline KLK1;ALB;CYP2E1 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways 30585:[DB06728 DB07700] DB06728|Aniline KLK1;ALB;CYP2E1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;AKR1C3 GO:0009267| cellular response to starvation ALB;AKR1C3 GO:0055114| oxidation-reduction process CYP2E1;AKR1C3 30586:[DB06728 DB01271] DB06728|Aniline KLK1;ALB;CYP2E1 DB01271|Idursulfase PLIN3 common genes common pathways 30587:[DB06728 DB09342] DB06728|Aniline KLK1;ALB;CYP2E1 DB09342|Propoxycaine CES1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 30588:[DB06728 DB07680] DB06728|Aniline KLK1;ALB;CYP2E1 DB07680|[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID CMA1 common genes common pathways GO:0006508| proteolysis CMA1;KLK1 30589:[DB06728 DB04951] DB06728|Aniline KLK1;ALB;CYP2E1 DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0044267| cellular protein metabolic process ALB;FURIN GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0006508| proteolysis FURIN;KLK1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 30590:[DB06728 DB09230] DB06728|Aniline KLK1;ALB;CYP2E1 DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30591:[DB06728 DB01264] DB06728|Aniline KLK1;ALB;CYP2E1 DB01264|Darunavir pol;CYP3A4;SLCO1B1;ABCB1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 30592:[DB06728 DB00850] DB06728|Aniline KLK1;ALB;CYP2E1 DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP2C19;CYP2C8;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2E1;CYP1A2;CYP2C18 GO:0002576| platelet degranulation CALM1;ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP1A2;CYP2C18 GO:0042493| response to drug DRD2;CYP1A2;CYP2E1;DRD1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C18;CYP2C9;CYP2B6;CYP2D6;CYP2C8;CYP2C19 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19 30593:[DB06728 DB04957] DB06728|Aniline KLK1;ALB;CYP2E1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A1;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP1A1;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A1 30594:[DB06728 DB04919] DB06728|Aniline KLK1;ALB;CYP2E1 DB04919|Alfimeprase FGA;FGB common genes common pathways GO:0044267| cellular protein metabolic process FGA;ALB GO:0002576| platelet degranulation FGB;FGA;ALB GO:0043687| post-translational protein modification ALB;FGA 30595:[DB06728 DB05679] DB06728|Aniline KLK1;ALB;CYP2E1 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways 30596:[DB06728 DB07017] DB06728|Aniline KLK1;ALB;CYP2E1 DB07017|(5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;HSD11B1 30597:[DB06728 DB13203] DB06728|Aniline KLK1;ALB;CYP2E1 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 30598:[DB06728 DB06479] DB06728|Aniline KLK1;ALB;CYP2E1 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 30599:[DB06728 DB08885] DB06728|Aniline KLK1;ALB;CYP2E1 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways GO:0002576| platelet degranulation ALB;VEGFA;VEGFB GO:0043066| negative regulation of apoptotic process ALB;VEGFA;VEGFB GO:0042493| response to drug PGF;CYP2E1;VEGFB 30600:[DB06728 DB03832] DB06728|Aniline KLK1;ALB;CYP2E1 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways 30601:[DB06728 DB02353] DB06728|Aniline KLK1;ALB;CYP2E1 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways 30602:[DB06728 DB11760] DB06728|Aniline KLK1;ALB;CYP2E1 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;CYP2E1 30603:[DB06728 DB08750] DB06728|Aniline KLK1;ALB;CYP2E1 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 30604:[DB06728 DB01456] DB06728|Aniline KLK1;ALB;CYP2E1 DB01456|5-androstenedione CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30605:[DB06728 DB02691] DB06728|Aniline KLK1;ALB;CYP2E1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1;SLCO1A2 GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B3;SLCO1B1;FABP6;ALB 30606:[DB06728 DB01889] DB06728|Aniline KLK1;ALB;CYP2E1 DB01889|16,17-Androstene-3-Ol NR1I3 common genes common pathways 30607:[DB06728 DB00614] DB06728|Aniline KLK1;ALB;CYP2E1 DB00614|Furazolidone MAOB;MAOA common genes common pathways GO:0045471| response to ethanol CYP2E1;MAOB GO:0042493| response to drug MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOB;CYP2E1;MAOA 30608:[DB06728 DB01733] DB06728|Aniline KLK1;ALB;CYP2E1 DB01733|L-Phospholactate PKM common genes common pathways 30609:[DB06728 DB01399] DB06728|Aniline KLK1;ALB;CYP2E1 DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;PTGS1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0098869| ALB;PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 30610:[DB06728 DB05514] DB06728|Aniline KLK1;ALB;CYP2E1 DB05514|Cobiprostone CLCN2 common genes common pathways 30611:[DB06728 DB07831] DB06728|Aniline KLK1;ALB;CYP2E1 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways 30612:[DB06728 DB07093] DB06728|Aniline KLK1;ALB;CYP2E1 DB07093|{3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 30613:[DB06728 DB01559] DB06728|Aniline KLK1;ALB;CYP2E1 DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2B6;CYP2C18;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;GABRG3 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C19;CYP2E1;CYP2C18 GO:0017144| drug metabolic process CYP2B6;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2B6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C18;CYP2B6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 30614:[DB06728 DB01272] DB06728|Aniline KLK1;ALB;CYP2E1 DB01272|Alglucosidase alfa M6PR common genes common pathways GO:0006898| receptor-mediated endocytosis M6PR;ALB 30615:[DB06728 DB09091] DB06728|Aniline KLK1;ALB;CYP2E1 DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0043066| negative regulation of apoptotic process HDAC2;ALB GO:0042493| response to drug CYP2E1;HDAC2 30616:[DB06728 DB07527] DB06728|Aniline KLK1;ALB;CYP2E1 DB07527|N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 30617:[DB06728 DB04394] DB06728|Aniline KLK1;ALB;CYP2E1 DB04394|3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide CA2 common genes common pathways 30618:[DB06728 DB07446] DB06728|Aniline KLK1;ALB;CYP2E1 DB07446|N-(biphenyl-4-ylsulfonyl)-D-leucine MMP12 common genes common pathways GO:0006508| proteolysis KLK1;MMP12 30619:[DB06728 DB04601] DB06728|Aniline KLK1;ALB;CYP2E1 DB04601|4-[(4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE CA2 common genes common pathways 30620:[DB06728 DB12141] DB06728|Aniline KLK1;ALB;CYP2E1 DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes ALB common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol HTR1B;HTR3A;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0042493| response to drug CYP2E1;HTR2A;HTR2C;HTR2B;ABCG2;ABCB1;HTR1B GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0010243| response to organic nitrogen FLT3;CYP2E1 GO:0043066| negative regulation of apoptotic process AXL;ALB;HTR2B GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 30621:[DB06728 DB00769] DB06728|Aniline KLK1;ALB;CYP2E1 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30622:[DB06728 DB07396] DB06728|Aniline KLK1;ALB;CYP2E1 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways 30623:[DB06728 DB05796] DB06728|Aniline KLK1;ALB;CYP2E1 DB05796|Daglutril MME common genes common pathways GO:0006508| proteolysis KLK1;MME 30624:[DB06728 DB00252] DB06728|Aniline KLK1;ALB;CYP2E1 DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP2C18;CYP3A4;CYP2E1;UGT1A6;CYP3A7;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP2B6;NR1I2;CYP2C9;UGT1A9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0098869| ALB GO:0017144| drug metabolic process CYP2B6;CYP2C9;UGT1A9;UGT1A1;CYP2D6;CYP2C8;CYP2C19;CYP3A4;CYP2E1;UGT1A6 GO:0043252| sodium-independent organic anion transport ALB;SLCO1C1 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP11B1;CYP3A7;CYP2C8;CYP2C19;CYP2D6;CYP3A5;NR1I2;CYP2B6;CYP2C9;UGT1A1 GO:0015721| bile acid and bile salt transport SLCO1C1;ALB GO:0044267| cellular protein metabolic process ALB GO:0019373| epoxygenase P450 pathway CYP2C18;CYP2E1;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0042493| response to drug ABCB1;ABCC2;UGT1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C19;CYP2C8;CYP3A7;CYP11B1;CYP3A4;CYP2E1;CYP2C18 GO:0043687| post-translational protein modification ALB 30625:[DB06728 DB00078] DB06728|Aniline KLK1;ALB;CYP2E1 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0006508| proteolysis C1QB;C1R;KLK1;C1QA;C1S;C1QC 30626:[DB06728 DB09140] DB06728|Aniline KLK1;ALB;CYP2E1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0098869| ALB;HBB;HBA1 GO:0055114| oxidation-reduction process CYP2E1;NOX1;MT-CO1 GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB 30627:[DB06728 DB04946] DB06728|Aniline KLK1;ALB;CYP2E1 DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes CYP2E1 common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0045471| response to ethanol DRD3;DRD2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0042493| response to drug DRD2;ADRA1A;DRD3;DRD1;HTR2A;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0010243| response to organic nitrogen CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 30628:[DB06728 DB01237] DB06728|Aniline KLK1;ALB;CYP2E1 DB01237|Bromodiphenhydramine HRH1;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB 30629:[DB06728 DB11614] DB06728|Aniline KLK1;ALB;CYP2E1 DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 30630:[DB06728 DB08259] DB06728|Aniline KLK1;ALB;CYP2E1 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways GO:0017144| drug metabolic process EPHX2;CYP2E1 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;EPHX2 30631:[DB06728 DB01738] DB06728|Aniline KLK1;ALB;CYP2E1 DB01738|Phosphorylcolamine PRKCB common genes common pathways 30632:[DB06728 DB14064] DB06728|Aniline KLK1;ALB;CYP2E1 DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 30633:[DB06728 DB03978] DB06728|Aniline KLK1;ALB;CYP2E1 DB03978|Tyrosinal tyrS;YARS;YARS common genes common pathways 30634:[DB06728 DB06814] DB06728|Aniline KLK1;ALB;CYP2E1 DB06814|Protokylol ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB2;ALB 30635:[DB06728 DB09239] DB06728|Aniline KLK1;ALB;CYP2E1 DB09239|Niguldipine ADRA1A;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 30636:[DB06728 DB08197] DB06728|Aniline KLK1;ALB;CYP2E1 DB08197|(5E,7S)-2-amino-7-(4-fluoro-2-pyridin-3-ylphenyl)-4-methyl-7,8-dihydroquinazolin-5(6H)-one oxime HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 30637:[DB06728 DB07919] DB06728|Aniline KLK1;ALB;CYP2E1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 30638:[DB06728 DB03945] DB06728|Aniline KLK1;ALB;CYP2E1 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways 30639:[DB06728 DB03736] DB06728|Aniline KLK1;ALB;CYP2E1 DB03736|2-Cyclopropylmethylenepropanal REN common genes common pathways GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug REN;CYP2E1 30640:[DB06728 DB09064] DB06728|Aniline KLK1;ALB;CYP2E1 DB09064|Ciprofibrate PPARA common genes common pathways 30641:[DB06728 DB06145] DB06728|Aniline KLK1;ALB;CYP2E1 DB06145|Spiramycin rplC;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30642:[DB06728 DB03451] DB06728|Aniline KLK1;ALB;CYP2E1 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways 30643:[DB06728 DB12118] DB06728|Aniline KLK1;ALB;CYP2E1 DB12118|Sotatercept ACVR2A common genes common pathways 30644:[DB06728 DB02039] DB06728|Aniline KLK1;ALB;CYP2E1 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways 30645:[DB06728 DB05234] DB06728|Aniline KLK1;ALB;CYP2E1 DB05234|LGD2941 AR common genes common pathways 30646:[DB06728 DB03016] DB06728|Aniline KLK1;ALB;CYP2E1 DB03016|CRA_1801 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 30647:[DB06728 DB05542] DB06728|Aniline KLK1;ALB;CYP2E1 DB05542|Naronapride HTR4 common genes common pathways 30648:[DB06728 DB08659] DB06728|Aniline KLK1;ALB;CYP2E1 DB08659|2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide CA2 common genes common pathways 30649:[DB06728 DB04757] DB06728|Aniline KLK1;ALB;CYP2E1 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug CYP2E1;PNP 30650:[DB06728 DB05463] DB06728|Aniline KLK1;ALB;CYP2E1 DB05463|ISS-1018 TLR9 common genes common pathways 30651:[DB06728 DB03435] DB06728|Aniline KLK1;ALB;CYP2E1 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways 30652:[DB06728 DB00773] DB06728|Aniline KLK1;ALB;CYP2E1 DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes CYP2E1 common pathways GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP1A2;CYP2C8;CYP3A5;GSTP1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1;GSTP1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;UGT1A1 GO:0010193| response to ozone CYP2E1 GO:0015721| bile acid and bile salt transport ABCC3;ALB GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1;CYP2C8 GO:0098869| GSTT1;ALB;GSTP1;PTGS2;PTGS1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A5;CYP2C8;UGT1A1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;PTGS1;CYP3A4;CYP2E1;PTGS2;CYP1A2 GO:0042493| response to drug ABCC2;ABCG2;ABCB1;ABCC1;ABCC6;UGT1A1;CYP2E1;PTGS2;CYP1A2 GO:0018910| benzene metabolic process CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB;GSTP1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1;CYP1A2 30653:[DB06728 DB04244] DB06728|Aniline KLK1;ALB;CYP2E1 DB04244|(2R)-2-(3-Biphenylyl)-N-{(2R)-2-hydroxy-3-[(2-pyridinylsulfonyl)amino]propyl}-4-methylpentanamide CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 30654:[DB06728 DB02267] DB06728|Aniline KLK1;ALB;CYP2E1 DB02267|Argininosuccinate ASL;argG common genes common pathways 30655:[DB06728 DB08159] DB06728|Aniline KLK1;ALB;CYP2E1 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 30656:[DB06728 DB08101] DB06728|Aniline KLK1;ALB;CYP2E1 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 30657:[DB06728 DB00580] DB06728|Aniline KLK1;ALB;CYP2E1 DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2E1;CYP2C9 GO:0042493| response to drug CYP2E1;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;UGT1A9;CYP2C9 GO:0098869| ALB;PTGS2 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;UGT1A9 GO:0045471| response to ethanol CA3;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 30658:[DB06728 DB00515] DB06728|Aniline KLK1;ALB;CYP2E1 DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ABCC3;ALB GO:0044267| cellular protein metabolic process ALB;TF GO:0017144| drug metabolic process CYP2E1;CYP2B6;CYP2C9 GO:0098869| PTGS2;GSTP1;ALB;GSTT1 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;SOD1;CYP4A11;PTGS2;XDH;MPO;CYP2C9;NQO1;CYP2B6 GO:0043687| post-translational protein modification ALB;TF GO:0042493| response to drug ABCC6;BCHE;ABCB1;ABCC2;ABCG2;PTGS2;SOD1;CYP2E1 GO:0002576| platelet degranulation ALB;TF;SOD1;A2M GO:0043066| negative regulation of apoptotic process MPO;PTGS2;SOD1;GSTP1;ALB;NQO1 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2C9;CYP4A11;CYP2E1 GO:0001895| retina homeostasis ALB;TF;SOD1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP2C9;NQO1;CYP2B6;GSTP1;CYP2E1 GO:0045471| response to ethanol SOD1;CYP2E1;NQO1;GSTP1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 30659:[DB06728 DB12688] DB06728|Aniline KLK1;ALB;CYP2E1 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways GO:0042493| response to drug CYP2E1;EEF2 GO:0045471| response to ethanol CYP2E1;EEF2 30660:[DB06728 DB00794] DB06728|Aniline KLK1;ALB;CYP2E1 DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19;CYP2C8;CYP2B6;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;UGT1A1;CYP2C8;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;UGT1A1;CYP2B6;CYP2C9;CYP2C8;CYP2C19 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug UGT1A1;CYP2E1;CYP1A2;GABRG3 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C19;CYP2C8;CYP2B6;CYP2C9 30661:[DB06728 DB02282] DB06728|Aniline KLK1;ALB;CYP2E1 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 30662:[DB06728 DB11869] DB06728|Aniline KLK1;ALB;CYP2E1 DB11869|Valspodar SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 30663:[DB06728 DB06039] DB06728|Aniline KLK1;ALB;CYP2E1 DB06039|PA-1050040 gag common genes common pathways 30664:[DB06728 DB02311] DB06728|Aniline KLK1;ALB;CYP2E1 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways 30665:[DB06728 DB04069] DB06728|Aniline KLK1;ALB;CYP2E1 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways GO:0043066| negative regulation of apoptotic process DAPK1;ALB 30666:[DB06728 DB00178] DB06728|Aniline KLK1;ALB;CYP2E1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis KLK1;ACE GO:0042493| response to drug BCHE;CYP2E1 30667:[DB06728 DB00592] DB06728|Aniline KLK1;ALB;CYP2E1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 30668:[DB06728 DB01160] DB06728|Aniline KLK1;ALB;CYP2E1 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A7;SLC22A11;SLCO3A1;SLC22A8;ALB;SLC22A6;SLCO2A1 GO:0043066| negative regulation of apoptotic process PTGFR;ALB 30669:[DB06728 DB13996] DB06728|Aniline KLK1;ALB;CYP2E1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;CYP2E1 30670:[DB06728 DB09571] DB06728|Aniline KLK1;ALB;CYP2E1 DB09571|Levmetamfetamine PNMT common genes common pathways 30671:[DB06728 DB09227] DB06728|Aniline KLK1;ALB;CYP2E1 DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30672:[DB06728 DB00815] DB06728|Aniline KLK1;ALB;CYP2E1 DB00815|Sodium lauryl sulfate ALB common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB 30673:[DB06728 DB00839] DB06728|Aniline KLK1;ALB;CYP2E1 DB00839|Tolazamide ABCC8;KCNJ11;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0042493| response to drug ABCC8;CYP2E1;KCNJ11 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 30674:[DB06728 DB03253] DB06728|Aniline KLK1;ALB;CYP2E1 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 30675:[DB06728 DB00925] DB06728|Aniline KLK1;ALB;CYP2E1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0002576| platelet degranulation ALB;CALM1 GO:0042493| response to drug CYP2E1;ADRA1A 30676:[DB06728 DB12418] DB06728|Aniline KLK1;ALB;CYP2E1 DB12418|Saccharin CA3 common genes common pathways GO:0045471| response to ethanol CYP2E1;CA3 30677:[DB06728 DB08162] DB06728|Aniline KLK1;ALB;CYP2E1 DB08162|Fasudil PKIA;PRKACA;ROCK1;ROCK2 common genes common pathways 30678:[DB06728 DB07837] DB06728|Aniline KLK1;ALB;CYP2E1 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways 30679:[DB06728 DB01811] DB06728|Aniline KLK1;ALB;CYP2E1 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways GO:0044267| cellular protein metabolic process LTF;ALB GO:0043066| negative regulation of apoptotic process ALB;LTF GO:0001895| retina homeostasis LTF;ALB GO:0006508| proteolysis LTF;KLK1 30680:[DB06728 DB00449] DB06728|Aniline KLK1;ALB;CYP2E1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A;BCHE GO:0006898| receptor-mediated endocytosis ADRB2;ALB 30681:[DB06728 DB12061] DB06728|Aniline KLK1;ALB;CYP2E1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0042493| response to drug CYP2E1;DRD3;DRD2 GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 30682:[DB06728 DB06215] DB06728|Aniline KLK1;ALB;CYP2E1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0044267| cellular protein metabolic process TF;ALB GO:0055114| oxidation-reduction process CYP2E1;FTH1 GO:0043687| post-translational protein modification TF;ALB GO:0002576| platelet degranulation TF;ALB GO:0001895| retina homeostasis TF;ALB 30683:[DB06728 DB01444] DB06728|Aniline KLK1;ALB;CYP2E1 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1 30684:[DB06728 DB09167] DB06728|Aniline KLK1;ALB;CYP2E1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2;CYP2C9;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C19 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP2C9 GO:0042493| response to drug ADRA1A;SLC6A2;SLC6A4;CYP1A2;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP2C9;CYP2C19;CYP2D6 30685:[DB06728 DB00446] DB06728|Aniline KLK1;ALB;CYP2E1 DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 30686:[DB06728 DB05417] DB06728|Aniline KLK1;ALB;CYP2E1 DB05417|GW 468816 GLRA1 common genes common pathways 30687:[DB06728 DB02338] DB06728|Aniline KLK1;ALB;CYP2E1 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0098869| ALB;TXNRD1 GO:0055114| oxidation-reduction process DPYD;TXNRD1;CYP2E1;AASS 30688:[DB06728 DB01973] DB06728|Aniline KLK1;ALB;CYP2E1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways GO:0006508| proteolysis KLK1;PRSS2 30689:[DB06728 DB00373] DB06728|Aniline KLK1;ALB;CYP2E1 DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C19;CYP2D6 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 30690:[DB06728 DB02508] DB06728|Aniline KLK1;ALB;CYP2E1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 30691:[DB06728 DB04113] DB06728|Aniline KLK1;ALB;CYP2E1 DB04113|N-Formylpiperidine ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;CYP2E1 30692:[DB06728 DB00319] DB06728|Aniline KLK1;ALB;CYP2E1 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A8 30693:[DB06728 DB02473] DB06728|Aniline KLK1;ALB;CYP2E1 DB02473|6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 30694:[DB06728 DB07664] DB06728|Aniline KLK1;ALB;CYP2E1 DB07664|5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE CSNK1G3;SLK;CAMK4;CLK3;ABL2 common genes common pathways 30695:[DB06728 DB08493] DB06728|Aniline KLK1;ALB;CYP2E1 DB08493|5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID MMP7 common genes common pathways GO:0006508| proteolysis KLK1;MMP7 30696:[DB06728 DB00393] DB06728|Aniline KLK1;ALB;CYP2E1 DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5;AHR GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 30697:[DB06728 DB03850] DB06728|Aniline KLK1;ALB;CYP2E1 DB03850|Jaspisamide A ACTA1 common genes common pathways 30698:[DB06728 DB09340] DB06728|Aniline KLK1;ALB;CYP2E1 DB09340|Tyropanoic acid GUSB common genes common pathways 30699:[DB06728 DB06248] DB06728|Aniline KLK1;ALB;CYP2E1 DB06248|Amelubant LTB4R2;LTB4R common genes common pathways 30700:[DB06728 DB00716] DB06728|Aniline KLK1;ALB;CYP2E1 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 30701:[DB06728 DB00825] DB06728|Aniline KLK1;ALB;CYP2E1 DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol OPRK1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;TRPA1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 30702:[DB06728 DB04685] DB06728|Aniline KLK1;ALB;CYP2E1 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways 30703:[DB06728 DB04072] DB06728|Aniline KLK1;ALB;CYP2E1 DB04072|Alpha-Methylisocitric Acid ACO2 common genes common pathways 30704:[DB06728 DB01105] DB06728|Aniline KLK1;ALB;CYP2E1 DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug SLC6A3;SLC6A2;SLC6A4;CYP2E1 GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30705:[DB06728 DB00030] DB06728|Aniline KLK1;ALB;CYP2E1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IGF1R GO:0002576| platelet degranulation SYTL4;ALB GO:0043687| post-translational protein modification ALB;IGFBP7 GO:0044267| cellular protein metabolic process IGFBP7;ALB GO:0006508| proteolysis PCSK2;CTSD;PCSK1;IDE;KLK1;CPE GO:0006898| receptor-mediated endocytosis LRP2;ALB 30706:[DB06728 DB00796] DB06728|Aniline KLK1;ALB;CYP2E1 DB00796|Candesartan cilexetil AGTR1;CYP2C9;CYP2C8;UGT1A3;PTGS1;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP2E1 GO:0017144| drug metabolic process UGT1A3;CYP2E1;CYP2C8;CYP2C9 GO:0098869| PTGS1;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;PTGS1;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 30707:[DB06728 DB00207] DB06728|Aniline KLK1;ALB;CYP2E1 DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2A6 GO:0042493| response to drug CYP2E1;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1 30708:[DB06728 DB08482] DB06728|Aniline KLK1;ALB;CYP2E1 DB08482|[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER MMP1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;MMP1 GO:0006508| proteolysis MMP1;KLK1 30709:[DB06728 DB01128] DB06728|Aniline KLK1;ALB;CYP2E1 DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 30710:[DB06728 DB06290] DB06728|Aniline KLK1;ALB;CYP2E1 DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes ALB common pathways GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;SLCO2B1;ALB GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport SLCO1B3;ABCB11;SLCO1B1;SLCO2B1;ALB;SLC10A1 GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1;ABCC2;ABCG2 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 30711:[DB06728 DB13967] DB06728|Aniline KLK1;ALB;CYP2E1 DB13967|Patent Blue ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 30712:[DB06728 DB07696] DB06728|Aniline KLK1;ALB;CYP2E1 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways GO:0006508| proteolysis KLK1;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0042493| response to drug CYP2E1;CASP3 30713:[DB06728 DB06287] DB06728|Aniline KLK1;ALB;CYP2E1 DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0009267| cellular response to starvation ALB;MTOR GO:0008202| steroid metabolic process CYP3A5;CYP2D6;CYP3A7;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP2E1;CYP2D6;CYP3A5 GO:0042493| response to drug CYP2E1;ABCB1 30714:[DB06728 DB13884] DB06728|Aniline KLK1;ALB;CYP2E1 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways GO:0002576| platelet degranulation F8;ALB GO:0055114| oxidation-reduction process CYP2E1;F8 GO:0006508| proteolysis KLK1;F10 30715:[DB06728 DB00275] DB06728|Aniline KLK1;ALB;CYP2E1 DB00275|Olmesartan AGTR1;ABCC2;SLCO1B3;SLCO1B1;ABCB11 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1B3 GO:0015721| bile acid and bile salt transport ALB;ABCB11;SLCO1B1;SLCO1B3 GO:0042493| response to drug CYP2E1;ABCC2 30716:[DB06728 DB03650] DB06728|Aniline KLK1;ALB;CYP2E1 DB03650|(3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 30717:[DB06728 DB11995] DB06728|Aniline KLK1;ALB;CYP2E1 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP2E1 GO:0042493| response to drug CYP2E1;ABCG2;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9;CYP2C8 GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 GO:0017144| drug metabolic process CYP2E1;CYP2C8;CYP2C9 30718:[DB06728 DB14600] DB06728|Aniline KLK1;ALB;CYP2E1 DB14600|Edetate disodium anhydrous ADA;CYP1A2;PON3;CYP19A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ADA;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug ADA;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP19A1;CYP1A2;CYP2E1 30719:[DB06728 DB06457] DB06728|Aniline KLK1;ALB;CYP2E1 DB06457|Tecastemizole KCNH2 common genes common pathways 30720:[DB06728 DB05413] DB06728|Aniline KLK1;ALB;CYP2E1 DB05413|Tifuvirtide SERPINA5 common genes common pathways 30721:[DB06728 DB07117] DB06728|Aniline KLK1;ALB;CYP2E1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process MMP9;ALB GO:0006508| proteolysis MMP9;KLK1 30722:[DB06728 DB06371] DB06728|Aniline KLK1;ALB;CYP2E1 DB06371|Siplizumab CD2 common genes common pathways 30723:[DB06728 DB06602] DB06728|Aniline KLK1;ALB;CYP2E1 DB06602|Reslizumab IL5 common genes common pathways 30724:[DB06728 DB04119] DB06728|Aniline KLK1;ALB;CYP2E1 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways 30725:[DB06728 DB00864] DB06728|Aniline KLK1;ALB;CYP2E1 DB00864|Tacrolimus FKBP1A;CYP3A7;CYP3A5;CYP3A4;ALB;ORM1;ABCB1;ABCA5;SLCO1B1 common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB;ABCA5 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0042493| response to drug CYP2E1;ABCB1 GO:0002576| platelet degranulation ALB;ORM1 GO:0043066| negative regulation of apoptotic process ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB 30726:[DB06728 DB07930] DB06728|Aniline KLK1;ALB;CYP2E1 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ACOX1 30727:[DB06728 DB11949] DB06728|Aniline KLK1;ALB;CYP2E1 DB11949|Vestipitant TACR1 common genes common pathways GO:0045471| response to ethanol TACR1;CYP2E1 GO:0010193| response to ozone TACR1;CYP2E1 30728:[DB06728 DB08059] DB06728|Aniline KLK1;ALB;CYP2E1 DB08059|Wortmannin PIK3CG;PLK1;PIK3R1;PIK3CA common genes common pathways GO:0043066| negative regulation of apoptotic process PLK1;ALB;PIK3R1 30729:[DB06728 DB00734] DB06728|Aniline KLK1;ALB;CYP2E1 DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug DRD3;DRD2;ADRA1A;HTR2C;CYP2E1;HTR2A;DRD1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol DRD2;DRD3;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP3A7;CYP3A4;CYP2E1 30730:[DB06728 DB07500] DB06728|Aniline KLK1;ALB;CYP2E1 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways 30731:[DB06728 DB03195] DB06728|Aniline KLK1;ALB;CYP2E1 DB03195|Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways 30732:[DB06728 DB01704] DB06728|Aniline KLK1;ALB;CYP2E1 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways GO:0006508| proteolysis KLK1;CTRB1 30733:[DB06728 DB12874] DB06728|Aniline KLK1;ALB;CYP2E1 DB12874|Quizartinib FLT3 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;FLT3 30734:[DB06728 DB08794] DB06728|Aniline KLK1;ALB;CYP2E1 DB08794|Ethyl biscoumacetate GLUL;CYP3A4 common genes common pathways GO:0009267| cellular response to starvation GLUL;ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 30735:[DB06728 DB05750] DB06728|Aniline KLK1;ALB;CYP2E1 DB05750|AVE-1625 CNR1 common genes common pathways GO:0045471| response to ethanol CYP2E1;CNR1 30736:[DB06728 DB07127] DB06728|Aniline KLK1;ALB;CYP2E1 DB07127|{4-[2,2-BIS(5-METHYL-1,2,4-OXADIAZOL-3-YL)-3-PHENYLPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways 30737:[DB06728 DB05394] DB06728|Aniline KLK1;ALB;CYP2E1 DB05394|Corticorelin DBH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DBH 30738:[DB06728 DB04115] DB06728|Aniline KLK1;ALB;CYP2E1 DB04115|Berberine BIRC5 common genes common pathways GO:0043066| negative regulation of apoptotic process BIRC5;ALB 30739:[DB06728 DB02660] DB06728|Aniline KLK1;ALB;CYP2E1 DB02660|Filaminast PDE4B common genes common pathways 30740:[DB06728 DB13781] DB06728|Aniline KLK1;ALB;CYP2E1 DB13781|Xamoterol ADRB1 common genes common pathways 30741:[DB06728 DB00465] DB06728|Aniline KLK1;ALB;CYP2E1 DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0098869| PTGS1;PTGS2;ALB 30742:[DB06728 DB00720] DB06728|Aniline KLK1;ALB;CYP2E1 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 30743:[DB06728 DB00653] DB06728|Aniline KLK1;ALB;CYP2E1 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways 30744:[DB06728 DB01147] DB06728|Aniline KLK1;ALB;CYP2E1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0009267| cellular response to starvation ALB 30745:[DB06728 DB02932] DB06728|Aniline KLK1;ALB;CYP2E1 DB02932|(R)-Bicalutamide AR common genes common pathways 30746:[DB06728 DB00573] DB06728|Aniline KLK1;ALB;CYP2E1 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;PTGS2;PTGS1 GO:0042493| response to drug PPARG;CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| PTGS1;PTGS2;ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 30747:[DB06728 DB00120] DB06728|Aniline KLK1;ALB;CYP2E1 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process TH;CYP2E1;PAH GO:0042493| response to drug CYP2E1;TH GO:0045471| response to ethanol CYP2E1;TH 30748:[DB06728 DB07677] DB06728|Aniline KLK1;ALB;CYP2E1 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 30749:[DB06728 DB09329] DB06728|Aniline KLK1;ALB;CYP2E1 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways GO:0002576| platelet degranulation VWF;ALB 30750:[DB06728 DB07592] DB06728|Aniline KLK1;ALB;CYP2E1 DB07592|(2R)-3-Methyl-1-phenyl-2-butanyl [(2S)-1-oxo-2-hexanyl]carbamate CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 30751:[DB06728 DB04117] DB06728|Aniline KLK1;ALB;CYP2E1 DB04117|4-(N,N-Dimethylamino)Cinnamoyl-Coa ECHS1 common genes common pathways 30752:[DB06728 DB02758] DB06728|Aniline KLK1;ALB;CYP2E1 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways 30753:[DB06728 DB00788] DB06728|Aniline KLK1;ALB;CYP2E1 DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2;PTGS1;CYP2C9;CYP2C8 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2;CYP2C9;UGT1A1;CYP2C8 GO:0098869| PTGS1;PTGS2;ALB GO:0008202| steroid metabolic process CYP2E1;CYP1A2;UGT2B7;CYP2C9;UGT1A1;CYP2C8 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1A2 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2;ABCB11 GO:0044267| cellular protein metabolic process ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8;CYP2C9 GO:0002576| platelet degranulation ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;PTGS1;CYP2E1;PTGS2;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP1A2;PTGS2;CYP2E1;UGT1A1 30754:[DB06728 DB07509] DB06728|Aniline KLK1;ALB;CYP2E1 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 30755:[DB06728 DB01267] DB06728|Aniline KLK1;ALB;CYP2E1 DB01267|Paliperidone HTR2A;DRD2;HRH1;ADRA1A;ADRA1B;DRD4;HTR1D;DRD3;HTR2C;ADRA2A;ADRA2B;ADRA2C;HTR1A;DRD1;HTR7;CYP3A4;CYP2D6;CYP3A5;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol DRD3;DRD2;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2D6;CYP2E1;CYP3A4 GO:0042493| response to drug HTR2C;ABCB1;ADRA1A;DRD2;DRD3;DRD1;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A5;CYP2D6 30756:[DB06728 DB00224] DB06728|Aniline KLK1;ALB;CYP2E1 DB00224|Indinavir pol;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;ABCB1;SLC22A1;ABCC1;SLCO1A2;SLCO1B1;ABCC2;SLCO2B1;ABCB11 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP3A5;UGT1A1;CYP3A4;CYP2E1;CYP3A7 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1A2;SLCO1B1 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;SLCO1A2;SLCO1B1;ABCB11 GO:0042493| response to drug CYP2E1;ABCB1;ABCC2;ABCC1;UGT1A1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2D6 GO:0045471| response to ethanol UGT1A1;CYP2E1 30757:[DB06728 DB01647] DB06728|Aniline KLK1;ALB;CYP2E1 DB01647|Daxalipram PDE4B common genes common pathways 30758:[DB06728 DB00869] DB06728|Aniline KLK1;ALB;CYP2E1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;CA3 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9 30759:[DB06728 DB02589] DB06728|Aniline KLK1;ALB;CYP2E1 DB02589|Se-Ethyl-Isoselenourea NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS3 30760:[DB06728 DB04276] DB06728|Aniline KLK1;ALB;CYP2E1 DB04276|N-[N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-Butyl]-Guanidine CAPN1 common genes common pathways GO:0006508| proteolysis CAPN1;KLK1 30761:[DB06728 DB03849] DB06728|Aniline KLK1;ALB;CYP2E1 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways 30762:[DB06728 DB07701] DB06728|Aniline KLK1;ALB;CYP2E1 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways 30763:[DB06728 DB02822] DB06728|Aniline KLK1;ALB;CYP2E1 DB02822|Para-Bromobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;CYP2E1 30764:[DB06728 DB11636] DB06728|Aniline KLK1;ALB;CYP2E1 DB11636|Nomegestrol CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 30765:[DB06728 DB07561] DB06728|Aniline KLK1;ALB;CYP2E1 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP2E1 GO:0042493| response to drug CYP2E1;DHODH 30766:[DB06728 DB00147] DB06728|Aniline KLK1;ALB;CYP2E1 DB00147|Pyridoxal PDXK common genes common pathways 30767:[DB06728 DB01541] DB06728|Aniline KLK1;ALB;CYP2E1 DB01541|Boldenone AR common genes common pathways 30768:[DB06728 DB00998] DB06728|Aniline KLK1;ALB;CYP2E1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;HTR1B GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0045471| response to ethanol HTR1B;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 30769:[DB06728 DB00133] DB06728|Aniline KLK1;ALB;CYP2E1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0042493| response to drug SRR;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CBS 30770:[DB06728 DB07252] DB06728|Aniline KLK1;ALB;CYP2E1 DB07252|3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide EPHB4 common genes common pathways 30771:[DB06728 DB05422] DB06728|Aniline KLK1;ALB;CYP2E1 DB05422|OPC-14523 SLC6A4 common genes common pathways GO:0042493| response to drug CYP2E1;SLC6A4 30772:[DB06728 DB13749] DB06728|Aniline KLK1;ALB;CYP2E1 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1;ADCY1 30773:[DB06728 DB12089] DB06728|Aniline KLK1;ALB;CYP2E1 DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30774:[DB06728 DB07173] DB06728|Aniline KLK1;ALB;CYP2E1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 30775:[DB06728 DB00539] DB06728|Aniline KLK1;ALB;CYP2E1 DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A1;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 30776:[DB06728 DB09061] DB06728|Aniline KLK1;ALB;CYP2E1 DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1B1;CYP2C9;CYP1A1;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process GPX1;CAT;PTGS2;HMGCR;SOD1;ALB;ADORA1 GO:0002576| platelet degranulation SOD1;ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 GO:0042493| response to drug CAT;CYP2E1;SOD1;HTR2A;PTGS2;CYP1A2;ABCG2;CYP1A1;PPARG;TRPA1;ABCC1;SMPD1 GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;ALOX15;CYP17A1;CYP2D6;IDO1;GSR;CYP2C19;CYP2C9;CYP1A1;CRYZ;ALOX5;GPX1;PTGS1;CAT;PTGS2;CYP3A7;CYP1A2;HMGCR;CYP3A4;CYP2E1;SOD1 GO:0098869| CAT;GPX1;PTGS1;PTGS2;GSR;ALB GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP1A1;CYP1B1;CYP2C19;CYP2D6;CYP17A1;CYP3A5;HMGCR;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0010193| response to ozone CAT;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2D6;CYP2C9;PTGS1;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0045471| response to ethanol HTR3A;CAT;CNR1;SOD1;CYP2E1;HMGCR;OPRM1 GO:0006641| triglyceride metabolic process CYP2E1;CAT;GPX1 GO:0001895| retina homeostasis SOD1;ALB 30777:[DB06728 DB08276] DB06728|Aniline KLK1;ALB;CYP2E1 DB08276|trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-) MYH14 common genes common pathways 30778:[DB06728 DB02890] DB06728|Aniline KLK1;ALB;CYP2E1 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways 30779:[DB06728 DB00066] DB06728|Aniline KLK1;ALB;CYP2E1 DB00066|Follitropin FSHR common genes common pathways 30780:[DB06728 DB01873] DB06728|Aniline KLK1;ALB;CYP2E1 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0002576| platelet degranulation ALB;TUBA4A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 30781:[DB06728 DB08809] DB06728|Aniline KLK1;ALB;CYP2E1 DB08809|Dichloroacetic Acid PDK1;GSTZ1 common genes common pathways GO:0098869| GSTZ1;ALB 30782:[DB06728 DB11595] DB06728|Aniline KLK1;ALB;CYP2E1 DB11595|Atezolizumab CD274 common genes common pathways 30783:[DB06728 DB01751] DB06728|Aniline KLK1;ALB;CYP2E1 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 30784:[DB06728 DB11135] DB06728|Aniline KLK1;ALB;CYP2E1 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways GO:0055114| oxidation-reduction process GSR;CYP2E1;TXNRD1 GO:0098869| TXNRD1;ALB;GSR 30785:[DB06728 DB01836] DB06728|Aniline KLK1;ALB;CYP2E1 DB01836|[4-(6-Chloro-Naphthalene-2-Sulfonyl)-Piperazin-1-Yl]-(3,4,5,6-Tetrahydro-2h-[1,4']Bipyridinyl-4-Yl)-Methanone PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 30786:[DB06728 DB00950] DB06728|Aniline KLK1;ALB;CYP2E1 DB00950|Fexofenadine HRH1;ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B3;SLC22A8;SLCO1B1;SLCO2B1;ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;SLCO1B3;ALB;SLCO2B1 30787:[DB06728 DB02774] DB06728|Aniline KLK1;ALB;CYP2E1 DB02774|1,3-Propandiol ARF1 common genes common pathways 30788:[DB06728 DB04856] DB06728|Aniline KLK1;ALB;CYP2E1 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5;CYP2C9 GO:0008202| steroid metabolic process CYP3A5;CYP2C9;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9 30789:[DB06728 DB01582] DB06728|Aniline KLK1;ALB;CYP2E1 DB01582|Sulfamethazine ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 30790:[DB06728 DB00397] DB06728|Aniline KLK1;ALB;CYP2E1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0042493| response to drug CYP2E1;DRD1 GO:0055114| oxidation-reduction process MAOA;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 30791:[DB06728 DB03944] DB06728|Aniline KLK1;ALB;CYP2E1 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 30792:[DB06728 DB03413] DB06728|Aniline KLK1;ALB;CYP2E1 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways 30793:[DB06728 DB04466] DB06728|Aniline KLK1;ALB;CYP2E1 DB04466|SR12813 NR1I2 common genes common pathways GO:0008202| steroid metabolic process NR1I2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;NR1I2 30794:[DB06728 DB07629] DB06728|Aniline KLK1;ALB;CYP2E1 DB07629|N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 30795:[DB06728 DB02115] DB06728|Aniline KLK1;ALB;CYP2E1 DB02115|Daidzin ALDH2;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ALDH2 GO:0042493| response to drug ABCG2;CYP2E1 30796:[DB06728 DB08786] DB06728|Aniline KLK1;ALB;CYP2E1 DB08786|4-(2-methoxyethoxy)-6-methylpyrimidin-2-amine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 30797:[DB06728 DB09310] DB06728|Aniline KLK1;ALB;CYP2E1 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 30798:[DB06728 DB03706] DB06728|Aniline KLK1;ALB;CYP2E1 DB03706|1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane GSTM4 common genes common pathways 30799:[DB06728 DB08047] DB06728|Aniline KLK1;ALB;CYP2E1 DB08047|4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 30800:[DB06728 DB05012] DB06728|Aniline KLK1;ALB;CYP2E1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0042493| response to drug CYP2E1;SLC6A2 30801:[DB06728 DB07681] DB06728|Aniline KLK1;ALB;CYP2E1 DB07681|DODECANESULFONATE ION BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 30802:[DB06728 DB07624] DB06728|Aniline KLK1;ALB;CYP2E1 DB07624|1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1 GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 30803:[DB06728 DB00728] DB06728|Aniline KLK1;ALB;CYP2E1 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0045471| response to ethanol CYP2E1;HTR3A GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 30804:[DB06728 DB02636] DB06728|Aniline KLK1;ALB;CYP2E1 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways 30805:[DB06728 DB02084] DB06728|Aniline KLK1;ALB;CYP2E1 DB02084|CRA_17312 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 30806:[DB06728 DB03026] DB06728|Aniline KLK1;ALB;CYP2E1 DB03026|Phosphoglycolohydroxamic Acid TPI1;fucA common genes common pathways 30807:[DB06728 DB03017] DB06728|Aniline KLK1;ALB;CYP2E1 DB03017|Lauric Acid ADH5;fabB;GM2A;fabH;HNF4A;PLA2G2A;VLDLR;GLTP;fabF;LTF;tonB;C8G;PLA2G2D;LY96;TLR4;PPARA;ALB common genes ALB common pathways GO:0006508| proteolysis LTF;KLK1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;HNF4A GO:0001895| retina homeostasis ALB;LTF GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis VLDLR;ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process ADH5;CYP2E1 GO:0043066| negative regulation of apoptotic process LTF;ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB;LTF GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;VLDLR GO:0098869| ALB 30808:[DB06728 DB00552] DB06728|Aniline KLK1;ALB;CYP2E1 DB00552|Pentostatin ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0042493| response to drug CYP2E1;ADA 30809:[DB06728 DB04436] DB06728|Aniline KLK1;ALB;CYP2E1 DB04436|3-Fluorotyrosine SOD2 common genes common pathways GO:0055114| oxidation-reduction process SOD2;CYP2E1 30810:[DB06728 DB03825] DB06728|Aniline KLK1;ALB;CYP2E1 DB03825|Rhodamine 6G ABCC1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1 30811:[DB06728 DB13876] DB06728|Aniline KLK1;ALB;CYP2E1 DB13876|Brofaromine MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 30812:[DB06728 DB04374] DB06728|Aniline KLK1;ALB;CYP2E1 DB04374|4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole HAO1 common genes common pathways GO:0055114| oxidation-reduction process HAO1;CYP2E1 30813:[DB06728 DB09047] DB06728|Aniline KLK1;ALB;CYP2E1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways 30814:[DB06728 DB00643] DB06728|Aniline KLK1;ALB;CYP2E1 DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0008202| steroid metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30815:[DB06728 DB00612] DB06728|Aniline KLK1;ALB;CYP2E1 DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 30816:[DB06728 DB01666] DB06728|Aniline KLK1;ALB;CYP2E1 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways 30817:[DB06728 DB04121] DB06728|Aniline KLK1;ALB;CYP2E1 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways 30818:[DB06728 DB07737] DB06728|Aniline KLK1;ALB;CYP2E1 DB07737|(2S)-4-(4-fluorobenzyl)-N-(3-sulfanylpropyl)piperazine-2-carboxamide BACE1 common genes common pathways GO:0006508| proteolysis BACE1;KLK1 GO:0044267| cellular protein metabolic process BACE1;ALB 30819:[DB06728 DB08631] DB06728|Aniline KLK1;ALB;CYP2E1 DB08631|N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 30820:[DB06728 DB06249] DB06728|Aniline KLK1;ALB;CYP2E1 DB06249|Arzoxifene ESR1;ESR2 common genes common pathways 30821:[DB06728 DB00213] DB06728|Aniline KLK1;ALB;CYP2E1 DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 30822:[DB06728 DB08564] DB06728|Aniline KLK1;ALB;CYP2E1 DB08564|(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 30823:[DB06728 DB03526] DB06728|Aniline KLK1;ALB;CYP2E1 DB03526|AL5927 CA2 common genes common pathways 30824:[DB06728 DB04941] DB06728|Aniline KLK1;ALB;CYP2E1 DB04941|Crofelemer CFTR;ANO1 common genes common pathways 30825:[DB06728 DB05897] DB06728|Aniline KLK1;ALB;CYP2E1 DB05897|rhIGFBP-3 IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process IGF1R;ALB 30826:[DB06728 DB06133] DB06728|Aniline KLK1;ALB;CYP2E1 DB06133|Dimethylcurcumin AR common genes common pathways 30827:[DB06728 DB07193] DB06728|Aniline KLK1;ALB;CYP2E1 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 30828:[DB06728 DB08922] DB06728|Aniline KLK1;ALB;CYP2E1 DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A1;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1;CYP2E1 GO:0042493| response to drug CYP1A1;ADRA1A;DRD2;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2D6;CYP1A1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A1;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A1;CYP2C8;CYP2D6 30829:[DB06728 DB07754] DB06728|Aniline KLK1;ALB;CYP2E1 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways GO:0006508| proteolysis KLK1;FOLH1 30830:[DB06728 DB12379] DB06728|Aniline KLK1;ALB;CYP2E1 DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0006805| xenobiotic metabolic process AHR;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A1 30831:[DB06728 DB01576] DB06728|Aniline KLK1;ALB;CYP2E1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0042493| response to drug SLC6A3;ADRA1A;SLC6A2;CYP2E1 30832:[DB06728 DB08329] DB06728|Aniline KLK1;ALB;CYP2E1 DB08329|Sulthiame CA2 common genes common pathways 30833:[DB06728 DB03615] DB06728|Aniline KLK1;ALB;CYP2E1 DB03615|Ribostamycin P4HB;rpsL common genes common pathways GO:0044267| cellular protein metabolic process P4HB;ALB GO:0055114| oxidation-reduction process CYP2E1;P4HB GO:0043687| post-translational protein modification ALB;P4HB 30834:[DB06728 DB00647] DB06728|Aniline KLK1;ALB;CYP2E1 DB00647|Dextropropoxyphene OPRM1;OPRD1;OPRK1;CES1;CYP3A4;CYP2D6;CYP2C8 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1;CES1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 30835:[DB06728 DB11560] DB06728|Aniline KLK1;ALB;CYP2E1 DB11560|Lesinurad SLC22A12;SLC22A11;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0042493| response to drug CYP2E1;SLC22A12 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A12;SLC22A11;ALB GO:0008202| steroid metabolic process CYP2C9;CYP2E1 30836:[DB06728 DB13999] DB06728|Aniline KLK1;ALB;CYP2E1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0006898| receptor-mediated endocytosis ASGR2;ALB;CALR;LRP1 GO:0006508| proteolysis PROC;KLK1;F9;F10;F2 GO:0044267| cellular protein metabolic process PROC;F2;ALB GO:0043066| negative regulation of apoptotic process PROC;HSPA5;ALB GO:0002576| platelet degranulation ALB;VWF GO:0055114| oxidation-reduction process CYP2E1;PHYH GO:0043687| post-translational protein modification PROC;ALB GO:0042493| response to drug CALR;CYP2E1 30837:[DB06728 DB05530] DB06728|Aniline KLK1;ALB;CYP2E1 DB05530|CPG 10101 TLR9 common genes common pathways 30838:[DB06728 DB07326] DB06728|Aniline KLK1;ALB;CYP2E1 DB07326|6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 30839:[DB06728 DB11598] DB06728|Aniline KLK1;ALB;CYP2E1 DB11598|Antithrombin III human SERPINC1 common genes common pathways GO:0044267| cellular protein metabolic process SERPINC1;ALB GO:0043687| post-translational protein modification SERPINC1;ALB 30840:[DB06728 DB06205] DB06728|Aniline KLK1;ALB;CYP2E1 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes ALB common pathways GO:0042493| response to drug TGFB1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB;TGFB1 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 30841:[DB06728 DB11450] DB06728|Aniline KLK1;ALB;CYP2E1 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 30842:[DB06728 DB01838] DB06728|Aniline KLK1;ALB;CYP2E1 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 30843:[DB06728 DB08020] DB06728|Aniline KLK1;ALB;CYP2E1 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways 30844:[DB06728 DB02236] DB06728|Aniline KLK1;ALB;CYP2E1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways 30845:[DB06728 DB00270] DB06728|Aniline KLK1;ALB;CYP2E1 DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30846:[DB06728 DB01185] DB06728|Aniline KLK1;ALB;CYP2E1 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0042493| response to drug CYP2E1;HSD11B2 GO:0055114| oxidation-reduction process HSD11B2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PRLR 30847:[DB06728 DB00606] DB06728|Aniline KLK1;ALB;CYP2E1 DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 30848:[DB06728 DB08320] DB06728|Aniline KLK1;ALB;CYP2E1 DB08320|DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 30849:[DB06728 DB01756] DB06728|Aniline KLK1;ALB;CYP2E1 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 30850:[DB06728 DB08022] DB06728|Aniline KLK1;ALB;CYP2E1 DB08022|(2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;ALB 30851:[DB06728 DB07512] DB06728|Aniline KLK1;ALB;CYP2E1 DB07512|7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE MAOB common genes common pathways GO:0042493| response to drug CYP2E1;MAOB GO:0055114| oxidation-reduction process MAOB;CYP2E1 GO:0045471| response to ethanol CYP2E1;MAOB 30852:[DB06728 DB08971] DB06728|Aniline KLK1;ALB;CYP2E1 DB08971|Fluocortolone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 30853:[DB06728 DB06926] DB06728|Aniline KLK1;ALB;CYP2E1 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 30854:[DB06728 DB00999] DB06728|Aniline KLK1;ALB;CYP2E1 DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB 30855:[DB06728 DB06691] DB06728|Aniline KLK1;ALB;CYP2E1 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 30856:[DB06728 DB13488] DB06728|Aniline KLK1;ALB;CYP2E1 DB13488|Bencyclane CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 30857:[DB06728 DB07318] DB06728|Aniline KLK1;ALB;CYP2E1 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 30858:[DB06728 DB08170] DB06728|Aniline KLK1;ALB;CYP2E1 DB08170|(1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE MMP7 common genes common pathways GO:0006508| proteolysis KLK1;MMP7 30859:[DB06728 DB08180] DB06728|Aniline KLK1;ALB;CYP2E1 DB08180|2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE FNTA;PGGT1B common genes common pathways 30860:[DB06728 DB08087] DB06728|Aniline KLK1;ALB;CYP2E1 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways 30861:[DB06728 DB00146] DB06728|Aniline KLK1;ALB;CYP2E1 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;CYP2E1;CYP27B1 30862:[DB06728 DB00741] DB06728|Aniline KLK1;ALB;CYP2E1 DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process ANXA1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP11B2;CYP11B1;CYP3A7;CYP2E1;CYP3A4;CYP2C8;HSD3B1;CYP3A5;HSD11B2 GO:0042493| response to drug ABCB1;HSD11B2;ANXA1;ABCG2;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP11B1;CYP11B2;CYP3A7;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP3A4;CYP2E1;CYP3A7 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 30863:[DB06728 DB01123] DB06728|Aniline KLK1;ALB;CYP2E1 DB01123|Proflavine F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis KLK1;F2 30864:[DB06728 DB06210] DB06728|Aniline KLK1;ALB;CYP2E1 DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2C8;UGT1A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;UGT1A9;UGT1A3;CYP2E1;CYP1A2 GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;ABCG2;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP2C8;UGT1A9 30865:[DB06728 DB08872] DB06728|Aniline KLK1;ALB;CYP2E1 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways 30866:[DB06728 DB03065] DB06728|Aniline KLK1;ALB;CYP2E1 DB03065|7-Nitroindazole-2-Carboxamidine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 30867:[DB06728 DB06421] DB06728|Aniline KLK1;ALB;CYP2E1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways 30868:[DB06728 DB13133] DB06728|Aniline KLK1;ALB;CYP2E1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0002576| platelet degranulation ALB;F8 GO:0042493| response to drug COL1A1;CYP2E1 GO:0055114| oxidation-reduction process F8;CYP2E1 GO:0006508| proteolysis KLK1;ADAMTS13 30869:[DB06728 DB07977] DB06728|Aniline KLK1;ALB;CYP2E1 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHODH GO:0042493| response to drug DHODH;CYP2E1 30870:[DB06728 DB00233] DB06728|Aniline KLK1;ALB;CYP2E1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process MPO;PTGS2;ALB GO:0055114| oxidation-reduction process CYP2E1;PTGS2;ALOX5;MPO GO:0042493| response to drug CYP2E1;PTGS2;CHUK GO:0010243| response to organic nitrogen PTGS2;CYP2E1 30871:[DB06728 DB03183] DB06728|Aniline KLK1;ALB;CYP2E1 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 30872:[DB06728 DB11606] DB06728|Aniline KLK1;ALB;CYP2E1 DB11606|Susoctocog alfa VWF common genes common pathways GO:0002576| platelet degranulation ALB;VWF 30873:[DB06728 DB05155] DB06728|Aniline KLK1;ALB;CYP2E1 DB05155|CR665 OPRK1 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRK1 30874:[DB06728 DB09080] DB06728|Aniline KLK1;ALB;CYP2E1 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C9;CYP2C8 30875:[DB06728 DB00585] DB06728|Aniline KLK1;ALB;CYP2E1 DB00585|Nizatidine HRH2;BCHE;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;BCHE;CYP2E1 30876:[DB06728 DB00561] DB06728|Aniline KLK1;ALB;CYP2E1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0042493| response to drug KCNK3;CYP2E1 30877:[DB06728 DB02144] DB06728|Aniline KLK1;ALB;CYP2E1 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways 30878:[DB06728 DB08026] DB06728|Aniline KLK1;ALB;CYP2E1 DB08026|2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide MAPK10 common genes common pathways 30879:[DB06728 DB03021] DB06728|Aniline KLK1;ALB;CYP2E1 DB03021|Ulapualide A ACTA1 common genes common pathways 30880:[DB06728 DB11455] DB06728|Aniline KLK1;ALB;CYP2E1 DB11455|Robenacoxib PTGS2 common genes common pathways GO:0098869| ALB;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 30881:[DB06728 DB01357] DB06728|Aniline KLK1;ALB;CYP2E1 DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C9;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 30882:[DB06728 DB07227] DB06728|Aniline KLK1;ALB;CYP2E1 DB07227|4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE FNTA;FNTB;PGGT1B common genes common pathways 30883:[DB06728 DB12598] DB06728|Aniline KLK1;ALB;CYP2E1 DB12598|Nafamostat F2;F10;F12;PRSS1;KLK1;ICAM1;SLC22A1;SLC22A2 common genes KLK1 common pathways GO:0045471| response to ethanol ICAM1;CYP2E1 GO:0006508| proteolysis F12;KLK1;PRSS1;F10;F2 GO:0044267| cellular protein metabolic process ALB;F2 GO:0042493| response to drug ICAM1;CYP2E1 30884:[DB06728 DB02955] DB06728|Aniline KLK1;ALB;CYP2E1 DB02955|Ricinoleic Acid CNR1;CNR2;TRPV1 common genes common pathways GO:0010243| response to organic nitrogen TRPV1;CYP2E1 GO:0045471| response to ethanol CYP2E1;CNR1 30885:[DB06728 DB13943] DB06728|Aniline KLK1;ALB;CYP2E1 DB13943|Testosterone cypionate AR;ESR1;NR3C2;CYP3A4;CYP19A1;MAOA;CYP11A1;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;SRD5A1;SRD5A2;SRD5A3;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;CYP1B1;CYP3A5;CYP2C19;CYP2C8;CYP3A7;CYP2E1;CYP2A13;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2A13;CYP2E1;CYP1B1;CYP2C8;CYP2C19;CYP2C9;CYP1A1;CYP2B6 GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;SRD5A1;SRD5A2;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A5;CYP1B1;CYP2B6;CYP2C9;CYP1A1;CYP19A1;SRD5A1;CYP3A43;CYP11A1;SRD5A2;SRD5A3;CYP2A13;CYP2E1;CYP3A4;MAOA;CYP3A7 GO:0098869| ALB GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2B6;CYP1A1;CYP2C9;CYP2E1;CYP3A4 GO:0009267| cellular response to starvation SRD5A1;ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A7;SLC22A8;SLCO1A2 GO:0008202| steroid metabolic process SRD5A1;CYP3A7;CYP11A1;SRD5A2;CYP2E1;CYP3A4;CYP1B1;CYP2C8;CYP2C19;CYP3A5;CYP2B6;CYP1A1;CYP2C9 GO:0015721| bile acid and bile salt transport ALB;SLC10A1;SLCO1A2 GO:0044267| cellular protein metabolic process ALB 30886:[DB06728 DB02553] DB06728|Aniline KLK1;ALB;CYP2E1 DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways GO:0098869| GSR;ALB GO:0055114| oxidation-reduction process CYP2E1;GSR 30887:[DB06728 DB04572] DB06728|Aniline KLK1;ALB;CYP2E1 DB04572|Thiotepa CYP2B6;CYP3A4;BCHE common genes common pathways GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2B6 GO:0042493| response to drug BCHE;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 30888:[DB06728 DB08529] DB06728|Aniline KLK1;ALB;CYP2E1 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 30889:[DB06728 DB00613] DB06728|Aniline KLK1;ALB;CYP2E1 DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C8;CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1B1;CYP2C8;CYP2D6;CYP1A1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP1B1;CYP2D6;CYP2C8;CYP1A1;CYP2C9 GO:0042493| response to drug CYP2E1;CYP1A1;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1;CYP1A1;CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2D6;CYP1B1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1;CYP2D6 30890:[DB06728 DB01197] DB06728|Aniline KLK1;ALB;CYP2E1 DB01197|Captopril ACE;MMP2;MMP9;LTA4H;BDKRB1;CYP2D6;ALB;ABCB1;SLC15A1;SLC22A6 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB;MMP9 GO:0002576| platelet degranulation ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0043687| post-translational protein modification ALB GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0044267| cellular protein metabolic process ALB;MMP2;LTA4H GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0006508| proteolysis MMP2;MMP9;KLK1;ACE;LTA4H GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 30891:[DB06728 DB09266] DB06728|Aniline KLK1;ALB;CYP2E1 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways GO:0006898| receptor-mediated endocytosis MRC1;ALB 30892:[DB06728 DB04054] DB06728|Aniline KLK1;ALB;CYP2E1 DB04054|9-Butyl-8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 30893:[DB06728 DB06641] DB06728|Aniline KLK1;ALB;CYP2E1 DB06641|Perifosine AKT1;MAPK1;PRKCA common genes common pathways GO:0043066| negative regulation of apoptotic process AKT1;ALB 30894:[DB06728 DB02011] DB06728|Aniline KLK1;ALB;CYP2E1 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways GO:0042493| response to drug CYP2E1;OTC 30895:[DB06728 DB04652] DB06728|Aniline KLK1;ALB;CYP2E1 DB04652|Corticosterone NR3C2;HSD11B1;NCOA1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;HSD11B1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process HSD11B1;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport NCOA1;ALB 30896:[DB06728 DB04709] DB06728|Aniline KLK1;ALB;CYP2E1 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways 30897:[DB06728 DB01612] DB06728|Aniline KLK1;ALB;CYP2E1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP2E1 30898:[DB06728 DB08152] DB06728|Aniline KLK1;ALB;CYP2E1 DB08152|{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 30899:[DB06728 DB01777] DB06728|Aniline KLK1;ALB;CYP2E1 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways 30900:[DB06728 DB09220] DB06728|Aniline KLK1;ALB;CYP2E1 DB09220|Nicorandil ABCC9 common genes common pathways GO:0042493| response to drug ABCC9;CYP2E1 30901:[DB06728 DB14518] DB06728|Aniline KLK1;ALB;CYP2E1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes KLK1;ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;APP;TF GO:0042493| response to drug CYP2E1;ATP1A1 GO:0043687| post-translational protein modification APP;ALB;TF GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process TF;ALB;APP GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006508| proteolysis KLK1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis TF;ALB 30902:[DB06728 DB07921] DB06728|Aniline KLK1;ALB;CYP2E1 DB07921|2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide MMP12 common genes common pathways GO:0006508| proteolysis MMP12;KLK1 30903:[DB06728 DB07684] DB06728|Aniline KLK1;ALB;CYP2E1 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways GO:0006508| proteolysis KLK1;PLAT 30904:[DB06728 DB00220] DB06728|Aniline KLK1;ALB;CYP2E1 DB00220|Nelfinavir CYP2B6;CYP2C19;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;CYP2C9;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2D6 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2D6;CYP3A7;CYP2E1;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1;ABCG2;CYP2E1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9;CYP2B6 GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;ABCB11;SLCO1B3;ALB;SLCO2B1 GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2B6;CYP2C9;CYP2D6;CYP2C19 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B3;SLCO1B1;SLCO2B1;ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2B6;CYP2C9;UGT1A1;CYP2D6;CYP2C19;CYP3A5;CYP3A4;CYP2E1;CYP3A7 30905:[DB06728 DB07300] DB06728|Aniline KLK1;ALB;CYP2E1 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways 30906:[DB06728 DB12733] DB06728|Aniline KLK1;ALB;CYP2E1 DB12733|Dipraglurant GRM5 common genes common pathways 30907:[DB06728 DB02735] DB06728|Aniline KLK1;ALB;CYP2E1 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways GO:0008202| steroid metabolic process STS;CYP2E1 GO:0043687| post-translational protein modification ALB;STS 30908:[DB06728 DB00867] DB06728|Aniline KLK1;ALB;CYP2E1 DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0055114| oxidation-reduction process PGD;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB 30909:[DB06728 DB00169] DB06728|Aniline KLK1;ALB;CYP2E1 DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C8;CYP2B6;CYP3A4;CYP2E1;CYP2J2 GO:0055114| oxidation-reduction process CYP11A1;CYP2E1;CYP2J2;CYP3A4;CYP2R1;CYP2C8;CYP2D6;CYP2B6;CYP1A1;CYP27A1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2J2;CYP2E1;CYP2C8;CYP1A1;CYP2B6 GO:0008202| steroid metabolic process CYP11A1;CYP2E1;CYP3A4;CYP2B6;CYP1A1;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2B6;CYP1A1;CYP2C8;CYP2D6 30910:[DB06728 DB02507] DB06728|Aniline KLK1;ALB;CYP2E1 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 30911:[DB06728 DB03280] DB06728|Aniline KLK1;ALB;CYP2E1 DB03280|P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate DTYMK;tmk;tmk common genes common pathways 30912:[DB06728 DB06150] DB06728|Aniline KLK1;ALB;CYP2E1 DB06150|Sulfadimethoxine CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 30913:[DB06728 DB03169] DB06728|Aniline KLK1;ALB;CYP2E1 DB03169|(S)-Hmg-Coa HMGCR common genes common pathways GO:0008202| steroid metabolic process HMGCR;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;HMGCR GO:0043066| negative regulation of apoptotic process ALB;HMGCR GO:0045471| response to ethanol CYP2E1;HMGCR 30914:[DB06728 DB11901] DB06728|Aniline KLK1;ALB;CYP2E1 DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2C9;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;GABRG3;ABCB1;ABCG2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8;CYP2C9 GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8;CYP2C9 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1B1;ALB 30915:[DB06728 DB00880] DB06728|Aniline KLK1;ALB;CYP2E1 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB 30916:[DB06728 DB04563] DB06728|Aniline KLK1;ALB;CYP2E1 DB04563|CRA_9678 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 30917:[DB06728 DB05495] DB06728|Aniline KLK1;ALB;CYP2E1 DB05495|PG-530742 MMP9 common genes common pathways GO:0006508| proteolysis KLK1;MMP9 GO:0043066| negative regulation of apoptotic process MMP9;ALB 30918:[DB06728 DB11113] DB06728|Aniline KLK1;ALB;CYP2E1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways 30919:[DB06728 DB11633] DB06728|Aniline KLK1;ALB;CYP2E1 DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5;CYP2D6;CYP2C19;CYP2C8;UGT1A9;CYP2C9;CYP2B6 GO:0042493| response to drug CYP2E1;KCNJ11;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP2B6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2B6;CYP2C9;UGT1A8;CYP2C8;CYP2C19;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2B6;UGT1A9;UGT1A8;CYP2D6;CYP2C19;CYP2C8 30920:[DB06728 DB01229] DB06728|Aniline KLK1;ALB;CYP2E1 DB01229|Paclitaxel TUBB1;BCL2;NR1I2;MAP4;MAP2;MAPT;CYP3A5;CYP3A7;CYP2C8;CYP3A4;CYP19A1;CYP1B1;ABCB11;ABCB1;ABCC1;ABCC10;SLCO1B3;ABCG2;ABCC2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP1B1;CYP19A1;CYP3A4;CYP2E1;CYP3A7 GO:0042493| response to drug ABCC1;ABCC2;ABCG2;ABCB1;CYP2E1;BCL2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1B1;CYP2C8 GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0015721| bile acid and bile salt transport SLCO1B3;ABCB11;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP1B1;NR1I2;CYP3A4;CYP2E1;CYP3A7 GO:0006805| xenobiotic metabolic process NR1I2;CYP1B1;CYP3A5;CYP2C8;CYP3A7;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 30921:[DB06728 DB12339] DB06728|Aniline KLK1;ALB;CYP2E1 DB12339|Radezolid RRBP1;NIP7 common genes common pathways 30922:[DB06728 DB11085] DB06728|Aniline KLK1;ALB;CYP2E1 DB11085|Resorcinol TPO common genes common pathways GO:0098869| TPO;ALB GO:0055114| oxidation-reduction process CYP2E1;TPO 30923:[DB06728 DB00372] DB06728|Aniline KLK1;ALB;CYP2E1 DB00372|Thiethylperazine DRD2;DRD1;DRD4 common genes common pathways GO:0042493| response to drug CYP2E1;DRD1;DRD2 GO:0045471| response to ethanol DRD2;CYP2E1 30924:[DB06728 DB07932] DB06728|Aniline KLK1;ALB;CYP2E1 DB07932|dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 30925:[DB06728 DB13772] DB06728|Aniline KLK1;ALB;CYP2E1 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 30926:[DB06728 DB12267] DB06728|Aniline KLK1;ALB;CYP2E1 DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP3A7;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0042493| response to drug ABCG2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A5;CYP3A7;CYP2E1;CYP3A4;CYP3A43 GO:0010243| response to organic nitrogen CYP2E1;FLT3 GO:0043066| negative regulation of apoptotic process ALB;EGFR;ERBB4;IGF1R GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2C8 30927:[DB06728 DB02159] DB06728|Aniline KLK1;ALB;CYP2E1 DB02159|(R)-Propylene glycol icd;LYZ common genes common pathways GO:0001895| retina homeostasis LYZ;ALB GO:0044267| cellular protein metabolic process LYZ;ALB 30928:[DB06728 DB03866] DB06728|Aniline KLK1;ALB;CYP2E1 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| PTGS2;ALB 30929:[DB06728 DB04828] DB06728|Aniline KLK1;ALB;CYP2E1 DB04828|Zomepirac PTGDR2;CYP3A4;ALB common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 30930:[DB06728 DB01926] DB06728|Aniline KLK1;ALB;CYP2E1 DB01926|Carboxymycobactin S LCN2 common genes common pathways 30931:[DB06728 DB02741] DB06728|Aniline KLK1;ALB;CYP2E1 DB02741|CD564 RARG common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 30932:[DB06728 DB07573] DB06728|Aniline KLK1;ALB;CYP2E1 DB07573|(2S)-1-(2,5-dimethylphenoxy)-3-morpholin-4-ylpropan-2-ol BACE1 common genes common pathways GO:0006508| proteolysis BACE1;KLK1 GO:0044267| cellular protein metabolic process BACE1;ALB 30933:[DB06728 DB04798] DB06728|Aniline KLK1;ALB;CYP2E1 DB04798|THIO-ATPA GRIA2 common genes common pathways 30934:[DB06728 DB06077] DB06728|Aniline KLK1;ALB;CYP2E1 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0042493| response to drug HTR2A;CYP2E1;DRD2 30935:[DB06728 DB07215] DB06728|Aniline KLK1;ALB;CYP2E1 DB07215|2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID NCOA1;PPARA common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA1 30936:[DB06728 DB03085] DB06728|Aniline KLK1;ALB;CYP2E1 DB03085|Glycolic acid G6PD;thiO common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;G6PD GO:0045471| response to ethanol CYP2E1;G6PD 30937:[DB06728 DB12579] DB06728|Aniline KLK1;ALB;CYP2E1 DB12579|JNJ-37822681 DRD2 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug DRD2;CYP2E1 30938:[DB06728 DB03773] DB06728|Aniline KLK1;ALB;CYP2E1 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways 30939:[DB06728 DB09074] DB06728|Aniline KLK1;ALB;CYP2E1 DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6 GO:0055114| oxidation-reduction process CYP2B6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2B6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 30940:[DB06728 DB07460] DB06728|Aniline KLK1;ALB;CYP2E1 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways GO:0043066| negative regulation of apoptotic process PTK2;ALB 30941:[DB06728 DB04564] DB06728|Aniline KLK1;ALB;CYP2E1 DB04564|Gluconolactone LCT common genes common pathways 30942:[DB06728 DB05116] DB06728|Aniline KLK1;ALB;CYP2E1 DB05116|Thymectacin TYMS common genes common pathways GO:0045471| response to ethanol TYMS;CYP2E1 GO:0042493| response to drug TYMS;CYP2E1 30943:[DB06728 DB00411] DB06728|Aniline KLK1;ALB;CYP2E1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways 30944:[DB06728 DB00918] DB06728|Aniline KLK1;ALB;CYP2E1 DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes CYP2E1 common pathways GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP2E1;HTR1B GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;FMO3;MAOA;CYP3A4;CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C19;FMO3 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0045471| response to ethanol HTR1B;CYP2E1 30945:[DB06728 DB00957] DB06728|Aniline KLK1;ALB;CYP2E1 DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug ABCC2;CYP2E1 30946:[DB06728 DB04860] DB06728|Aniline KLK1;ALB;CYP2E1 DB04860|Isatoribine TLR7 common genes common pathways 30947:[DB06728 DB07734] DB06728|Aniline KLK1;ALB;CYP2E1 DB07734|N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis BACE1;KLK1 30948:[DB06728 DB00291] DB06728|Aniline KLK1;ALB;CYP2E1 DB00291|Chlorambucil GSTP1;SLCO1A2 common genes common pathways GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0043252| sodium-independent organic anion transport SLCO1A2;ALB GO:0098869| GSTP1;ALB 30949:[DB06728 DB00841] DB06728|Aniline KLK1;ALB;CYP2E1 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0042493| response to drug COMT;ADRA1A;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 30950:[DB06728 DB08228] DB06728|Aniline KLK1;ALB;CYP2E1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;NQO2 GO:0055114| oxidation-reduction process CYP2E1;NQO2 30951:[DB06728 DB05046] DB06728|Aniline KLK1;ALB;CYP2E1 DB05046|V1003 OPRK1;OPRM1 common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 30952:[DB06728 DB11817] DB06728|Aniline KLK1;ALB;CYP2E1 DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;PTK2B GO:0010243| response to organic nitrogen CYP2E1;PTK2B GO:0042493| response to drug CYP2E1;PTK2B;ABCG2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process PTK2B;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B3 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1B3;SLC22A6;ALB 30953:[DB06728 DB06871] DB06728|Aniline KLK1;ALB;CYP2E1 DB06871|17-METHYL-17-ALPHA-DIHYDROEQUILENIN ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 30954:[DB06728 DB06901] DB06728|Aniline KLK1;ALB;CYP2E1 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways GO:0006508| proteolysis KLK1;CELA2A 30955:[DB06728 DB07691] DB06728|Aniline KLK1;ALB;CYP2E1 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways GO:0043066| negative regulation of apoptotic process PPARD;ALB 30956:[DB06728 DB01214] DB06728|Aniline KLK1;ALB;CYP2E1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 30957:[DB06728 DB05203] DB06728|Aniline KLK1;ALB;CYP2E1 DB05203|SPP1148 ACE2;REN common genes common pathways GO:0042493| response to drug CYP2E1;REN GO:0006508| proteolysis ACE2;KLK1;REN 30958:[DB06728 DB00044] DB06728|Aniline KLK1;ALB;CYP2E1 DB00044|Lutropin alfa LHCGR common genes common pathways 30959:[DB06728 DB08808] DB06728|Aniline KLK1;ALB;CYP2E1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 30960:[DB06728 DB09092] DB06728|Aniline KLK1;ALB;CYP2E1 DB09092|Xanthinol RPL3;NNT;GAPDH;IDH3A;OGDH;MDH2 common genes common pathways GO:0055114| oxidation-reduction process MDH2;IDH3A;CYP2E1;GAPDH;NNT;OGDH 30961:[DB06728 DB07693] DB06728|Aniline KLK1;ALB;CYP2E1 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 30962:[DB06728 DB07253] DB06728|Aniline KLK1;ALB;CYP2E1 DB07253|N'-(5-chloro-1,3-benzodioxol-4-yl)-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine EPHB4 common genes common pathways 30963:[DB06728 DB09290] DB06728|Aniline KLK1;ALB;CYP2E1 DB09290|Ramosetron HTR3A;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0045471| response to ethanol HTR3A;CYP2E1 30964:[DB06728 DB07530] DB06728|Aniline KLK1;ALB;CYP2E1 DB07530|(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol NCOA1;VDR common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA1 30965:[DB06728 DB14059] DB06728|Aniline KLK1;ALB;CYP2E1 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0098869| ALB;PTGS2 GO:0042493| response to drug PTGS2;RELA;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;NFKB1;PTGS2;RELA 30966:[DB06728 DB06064] DB06728|Aniline KLK1;ALB;CYP2E1 DB06064|KAI-1455 PRKCE common genes common pathways 30967:[DB06728 DB08025] DB06728|Aniline KLK1;ALB;CYP2E1 DB08025|N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE MAPK10 common genes common pathways 30968:[DB06728 DB07517] DB06728|Aniline KLK1;ALB;CYP2E1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB 30969:[DB06728 DB08157] DB06728|Aniline KLK1;ALB;CYP2E1 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways 30970:[DB06728 DB01309] DB06728|Aniline KLK1;ALB;CYP2E1 DB01309|Insulin Glulisine INSR common genes common pathways 30971:[DB06728 DB00040] DB06728|Aniline KLK1;ALB;CYP2E1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 30972:[DB06728 DB04016] DB06728|Aniline KLK1;ALB;CYP2E1 DB04016|2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid CTSG;CMA1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;CTSG GO:0006508| proteolysis CTSG;CMA1;KLK1 30973:[DB06728 DB00309] DB06728|Aniline KLK1;ALB;CYP2E1 DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 30974:[DB06728 DB11087] DB06728|Aniline KLK1;ALB;CYP2E1 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0006805| xenobiotic metabolic process NR1I2;CYP2E1 GO:0008202| steroid metabolic process NR1I2;CYP2E1 30975:[DB06728 DB06736] DB06728|Aniline KLK1;ALB;CYP2E1 DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2;CYP2C9 GO:0042493| response to drug PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0098869| PTGS1;PTGS2;ALB GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;PTGS1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 30976:[DB06728 DB11988] DB06728|Aniline KLK1;ALB;CYP2E1 DB11988|Ocrelizumab MS4A1 common genes common pathways 30977:[DB06728 DB00625] DB06728|Aniline KLK1;ALB;CYP2E1 DB00625|Efavirenz pol;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP2C8;UGT1A1;ALB;ABCB11;SLC22A1 common genes ALB common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP2B6;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug UGT1A1;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ABCB11;ALB 30978:[DB06728 DB01700] DB06728|Aniline KLK1;ALB;CYP2E1 DB01700|AICA ribonucleotide ATIC common genes common pathways 30979:[DB06728 DB00994] DB06728|Aniline KLK1;ALB;CYP2E1 DB00994|Neomycin rpsL;CASR common genes common pathways 30980:[DB06728 DB05455] DB06728|Aniline KLK1;ALB;CYP2E1 DB05455|SR 121463 AVPR1B common genes common pathways 30981:[DB06728 DB03329] DB06728|Aniline KLK1;ALB;CYP2E1 DB03329|2-Pyridinethiol CTSB common genes common pathways GO:0006508| proteolysis KLK1;CTSB 30982:[DB06728 DB14034] DB06728|Aniline KLK1;ALB;CYP2E1 DB14034|Darglitazone PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 30983:[DB06728 DB04269] DB06728|Aniline KLK1;ALB;CYP2E1 DB04269|Cyclotheonamide A PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 30984:[DB06728 DB03100] DB06728|Aniline KLK1;ALB;CYP2E1 DB03100|6-Nitroindazole NOS2;NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;NOS2;CYP2E1 30985:[DB06728 DB09102] DB06728|Aniline KLK1;ALB;CYP2E1 DB09102|Daclatasvir CYP3A5;CYP3A4;CYP3A43;CYP3A7;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP2E1;CYP3A7;CYP3A43 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1B3 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 30986:[DB06728 DB05959] DB06728|Aniline KLK1;ALB;CYP2E1 DB05959|ENMD-1198 TNFRSF11A;HIF1A;STAT3 common genes common pathways GO:0045471| response to ethanol CYP2E1;STAT3 GO:0043687| post-translational protein modification ALB;HIF1A GO:0042493| response to drug STAT3;CYP2E1 GO:0043066| negative regulation of apoptotic process STAT3;HIF1A;ALB 30987:[DB06728 DB07559] DB06728|Aniline KLK1;ALB;CYP2E1 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0042493| response to drug DHODH;CYP2E1 GO:0055114| oxidation-reduction process DHODH;CYP2E1 30988:[DB06728 DB00640] DB06728|Aniline KLK1;ALB;CYP2E1 DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways GO:0044267| cellular protein metabolic process ALB;ADORA2B;ADORA2A GO:0042493| response to drug CYP2E1;ADA;ADORA2A GO:0043066| negative regulation of apoptotic process ADORA1;ALB;ADA 30989:[DB06728 DB04429] DB06728|Aniline KLK1;ALB;CYP2E1 DB04429|4'-Hydroxyflavanone SHBG common genes common pathways 30990:[DB06728 DB05018] DB06728|Aniline KLK1;ALB;CYP2E1 DB05018|Migalastat GLA;UGT1A1 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1 30991:[DB06728 DB00674] DB06728|Aniline KLK1;ALB;CYP2E1 DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0042493| response to drug CYP2E1;BCHE GO:0045471| response to ethanol CHRNB2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 30992:[DB06728 DB08692] DB06728|Aniline KLK1;ALB;CYP2E1 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways GO:0006508| proteolysis KLK1;CTRB1 30993:[DB06728 DB04881] DB06728|Aniline KLK1;ALB;CYP2E1 DB04881|Elacridar ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 30994:[DB06728 DB03962] DB06728|Aniline KLK1;ALB;CYP2E1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways GO:0055114| oxidation-reduction process PGD;CYP2E1 30995:[DB06728 DB06153] DB06728|Aniline KLK1;ALB;CYP2E1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0042493| response to drug HTR2C;HTR2B;HTR1B;ADRA1A;CYP2E1;HTR2A GO:0045471| response to ethanol HTR1B;CYP2E1 30996:[DB06728 DB08099] DB06728|Aniline KLK1;ALB;CYP2E1 DB08099|6-ethyl-5-[(2S)-1-(3-methoxypropyl)-2-phenyl-1,2,3,4-tetrahydroquinolin-7-yl]pyrimidine-2,4-diamine REN common genes common pathways GO:0042493| response to drug REN;CYP2E1 GO:0006508| proteolysis KLK1;REN 30997:[DB06728 DB08736] DB06728|Aniline KLK1;ALB;CYP2E1 DB08736|S,R-Warfarin alcohol ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB 30998:[DB06728 DB00695] DB06728|Aniline KLK1;ALB;CYP2E1 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes ALB common pathways GO:0017144| drug metabolic process CYP2E1;UGT1A1 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A11;SLCO2A1;SLC22A6;ALB GO:0008202| steroid metabolic process UGT1A1;CYP2E1 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP2E1;PGD GO:0043687| post-translational protein modification ALB GO:0042493| response to drug UGT1A1;ABCC2;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 30999:[DB06728 DB00911] DB06728|Aniline KLK1;ALB;CYP2E1 DB00911|Tinidazole CYP3A4;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31000:[DB06728 DB13152] DB06728|Aniline KLK1;ALB;CYP2E1 DB13152|Coagulation Factor IX Human F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0006508| proteolysis F10;F7;F2;F11;KLK1 GO:0006898| receptor-mediated endocytosis LRP1;ALB GO:0055114| oxidation-reduction process F8;CYP2E1 GO:0002576| platelet degranulation F8;ALB GO:0044267| cellular protein metabolic process ALB;F2 31001:[DB06728 DB09129] DB06728|Aniline KLK1;ALB;CYP2E1 DB09129|Chromic chloride INSR common genes common pathways 31002:[DB06728 DB06796] DB06728|Aniline KLK1;ALB;CYP2E1 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes ALB common pathways GO:0055114| oxidation-reduction process SOD2;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;A2M GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB 31003:[DB06728 DB06533] DB06728|Aniline KLK1;ALB;CYP2E1 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 31004:[DB06728 DB06472] DB06728|Aniline KLK1;ALB;CYP2E1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0002576| platelet degranulation ITGB3;ALB;ITGA2B 31005:[DB06728 DB07247] DB06728|Aniline KLK1;ALB;CYP2E1 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways GO:0006508| proteolysis F7;KLK1 31006:[DB06728 DB07140] DB06728|Aniline KLK1;ALB;CYP2E1 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP2E1 31007:[DB06728 DB00384] DB06728|Aniline KLK1;ALB;CYP2E1 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 31008:[DB06728 DB05916] DB06728|Aniline KLK1;ALB;CYP2E1 DB05916|CT-011 PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PDCD1;ALB 31009:[DB06728 DB07814] DB06728|Aniline KLK1;ALB;CYP2E1 DB07814|Gibberellic acid AADACL2 common genes common pathways 31010:[DB06728 DB01902] DB06728|Aniline KLK1;ALB;CYP2E1 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways GO:0055114| oxidation-reduction process ERO1B;CYP2E1 31011:[DB06728 DB00060] DB06728|Aniline KLK1;ALB;CYP2E1 DB00060|Interferon beta-1a IFNAR1;IFNAR2 common genes common pathways 31012:[DB06728 DB02568] DB06728|Aniline KLK1;ALB;CYP2E1 DB02568|Peldesine PNP common genes common pathways GO:0042493| response to drug CYP2E1;PNP 31013:[DB06728 DB04446] DB06728|Aniline KLK1;ALB;CYP2E1 DB04446|Benzo[B]Thiophene-2-Carboxamidine PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 31014:[DB06728 DB00906] DB06728|Aniline KLK1;ALB;CYP2E1 DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug UGT1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0010243| response to organic nitrogen SLC6A1;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31015:[DB06728 DB04495] DB06728|Aniline KLK1;ALB;CYP2E1 DB04495|RU81843 SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 31016:[DB06728 DB02271] DB06728|Aniline KLK1;ALB;CYP2E1 DB02271|S-(2-Oxo)Pentadecylcoa NMT2 common genes common pathways 31017:[DB06728 DB07079] DB06728|Aniline KLK1;ALB;CYP2E1 DB07079|3-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}propane-1-thiol ADAM17 common genes common pathways GO:0042493| response to drug CYP2E1;ADAM17 GO:0006508| proteolysis ADAM17;KLK1 31018:[DB06728 DB02838] DB06728|Aniline KLK1;ALB;CYP2E1 DB02838|3,4-Dihydro-2h-Pyrrolium-5-Carboxylate DAO common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DAO 31019:[DB06728 DB06750] DB06728|Aniline KLK1;ALB;CYP2E1 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO1B3;ALB GO:0015721| bile acid and bile salt transport SLCO1B3;ALB 31020:[DB06728 DB00743] DB06728|Aniline KLK1;ALB;CYP2E1 DB00743|Gadobenic acid ALB common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 31021:[DB06728 DB03609] DB06728|Aniline KLK1;ALB;CYP2E1 DB03609|3-Deoxyguanosine PNP common genes common pathways GO:0042493| response to drug PNP;CYP2E1 31022:[DB06728 DB13949] DB06728|Aniline KLK1;ALB;CYP2E1 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TF GO:0002576| platelet degranulation TF;ITGB3;ALB GO:0043687| post-translational protein modification TF;ALB GO:0042493| response to drug CALR;CYP2E1 GO:0006898| receptor-mediated endocytosis TFRC;ALB;CALR GO:0001895| retina homeostasis TF;ALB 31023:[DB06728 DB04791] DB06728|Aniline KLK1;ALB;CYP2E1 DB04791|2-O-(4'-AMIDINOPHENYL)-5-O-(3''-AMIDINOPHENYL)-1,4:3,6-DIANHYDRO-D-SORBITOL PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 31024:[DB06728 DB08756] DB06728|Aniline KLK1;ALB;CYP2E1 DB08756|(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE PRKACA;PKIA;ROCK1;ROCK2 common genes common pathways 31025:[DB06728 DB04404] DB06728|Aniline KLK1;ALB;CYP2E1 DB04404|Allosamizoline CHIT1 common genes common pathways 31026:[DB06728 DB08811] DB06728|Aniline KLK1;ALB;CYP2E1 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0042493| response to drug PDE3A;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31027:[DB06728 DB01092] DB06728|Aniline KLK1;ALB;CYP2E1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1 GO:0042493| response to drug CYP2E1;ATP1A1;CYP1A1;ATP1A3 GO:0017144| drug metabolic process CYP1A1;CYP2E1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;SLCO1B1;SLCO1B3;SLCO1C1;ALB;SLCO4C1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;SLCO1A2;ALB;SLCO1C1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1 31028:[DB06728 DB01428] DB06728|Aniline KLK1;ALB;CYP2E1 DB01428|Oxybenzone PGR;AR;ESR1;ESR2 common genes common pathways 31029:[DB06728 DB07772] DB06728|Aniline KLK1;ALB;CYP2E1 DB07772|(1R)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid MMP8 common genes common pathways GO:0006508| proteolysis MMP8;KLK1 31030:[DB06728 DB01077] DB06728|Aniline KLK1;ALB;CYP2E1 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 31031:[DB06728 DB03255] DB06728|Aniline KLK1;ALB;CYP2E1 DB03255|Phenol cobT;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB 31032:[DB06728 DB07437] DB06728|Aniline KLK1;ALB;CYP2E1 DB07437|1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE UPP1 common genes common pathways 31033:[DB06728 DB07710] DB06728|Aniline KLK1;ALB;CYP2E1 DB07710|PHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE CA2 common genes common pathways 31034:[DB06728 DB05125] DB06728|Aniline KLK1;ALB;CYP2E1 DB05125|SC12267 DHODH common genes common pathways GO:0042493| response to drug DHODH;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;DHODH 31035:[DB06728 DB04892] DB06728|Aniline KLK1;ALB;CYP2E1 DB04892|Phenserine ACHE;BCHE;APP common genes common pathways GO:0002576| platelet degranulation ALB;APP GO:0042493| response to drug BCHE;CYP2E1 GO:0043687| post-translational protein modification ALB;APP GO:0044267| cellular protein metabolic process APP;ALB 31036:[DB06728 DB05487] DB06728|Aniline KLK1;ALB;CYP2E1 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways GO:0043066| negative regulation of apoptotic process NFKB1;ALB 31037:[DB06728 DB04442] DB06728|Aniline KLK1;ALB;CYP2E1 DB04442|2-(2-Oxo-1,2-Dihydro-Pyridin-3-Yl)-1h-Benzoimidazole-5-Carboxamidine PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 31038:[DB06728 DB00942] DB06728|Aniline KLK1;ALB;CYP2E1 DB00942|Cycrimine CHRM1 common genes common pathways 31039:[DB06728 DB02761] DB06728|Aniline KLK1;ALB;CYP2E1 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways 31040:[DB06728 DB08201] DB06728|Aniline KLK1;ALB;CYP2E1 DB08201|(1S)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 31041:[DB06728 DB08860] DB06728|Aniline KLK1;ALB;CYP2E1 DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0045471| response to ethanol CYP2E1;HMGCR GO:0015721| bile acid and bile salt transport SLC10A1;SLCO2B1;ALB;SLCO1B3;ABCB11;SLCO1B1 GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;UGT1A3;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2E1;HMGCR;UGT2B7;CYP2C9;CYP2C8 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1B3;SLCO1B1 GO:0042493| response to drug ABCB1;ABCG2;ABCC2;CYP2E1 GO:0055114| oxidation-reduction process HMGCR;CYP2E1;CYP2C9;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ORM1;ALB GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 31042:[DB06728 DB12010] DB06728|Aniline KLK1;ALB;CYP2E1 DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2E1;CYP3A4 GO:0009267| cellular response to starvation BMPR2;MTOR;PIK3C2B;ALB;STK24;LRRK2;STK26 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;PRKAA1;UGT1A1;PRKAA2 GO:0010243| response to organic nitrogen CYP2E1;FLT3;CDK1;PTK2B GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;ALOX5 GO:0042493| response to drug LCK;MAP2K6;ABCG2;PTK2B;UGT1A1;LYN;NTRK1;FYN;RET;SRC;CDK4;CDK1;TGFBR2;CYP2E1 GO:0043066| negative regulation of apoptotic process PLK2;RPS6KA1;PLK3;PRKAA2;PDGFRB;RPS6KA3;RIPK2;PAK2;NTRK1;IRAK1;PTK2;MAP4K4;FLT4;NUAK2;TEK;BRAF;PRKAA1;EGFR;KDR;MAPK7;PTK2B;PIM3;ALB;PIM1;HIPK3;CDK1;RAF1;AXL;LTK;CAMK1D;ERBB4;IKBKB;DAPK1;PRKCI;SRC;AURKA;HCK;CSF1R;PLK1;TGFBR1;EIF2AK2;GSK3B GO:0002576| platelet degranulation ALB;LYN GO:0006898| receptor-mediated endocytosis GAK;ALB;TGFBR2;PI4KB GO:0043069| negative regulation of programmed cell death KIT;ALB GO:0006508| proteolysis KLK1;CTSL;CTSS GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;UGT1A9 GO:0045471| response to ethanol CDK1;CYP2E1;FGFR2;UGT1A1;FYN;NTRK3;PTK2B GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1 31043:[DB06728 DB04761] DB06728|Aniline KLK1;ALB;CYP2E1 DB04761|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] MMP13 common genes common pathways GO:0044267| cellular protein metabolic process MMP13;ALB GO:0006508| proteolysis MMP13;KLK1 31044:[DB06728 DB08077] DB06728|Aniline KLK1;ALB;CYP2E1 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBA1;HBB GO:0098869| ALB;HBB;HBA1 31045:[DB06728 DB14533] DB06728|Aniline KLK1;ALB;CYP2E1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0008202| steroid metabolic process APOL1;CYP2E1;APOE;APOBR;APOA1 GO:0098869| S100A9;HBB;HBA1;APOE;ALB GO:0044267| cellular protein metabolic process F2;KNG1;FGA;ALB;APOA1;AHSG;IGFALS;APP;APOA2;APOA4;APOE;FN1;SEMG1;SERPIND1;CP;SERPINA1;TTR;INS;TF;APCS;GSN;P4HB;APOL1;ITIH2;C3;APLP2 GO:0043066| negative regulation of apoptotic process SOD1;MGMT;MT3;HDAC1;MMP9;MDM2;TP53;ALB GO:0002576| platelet degranulation A2M;SERPINA1;TF;APLP2;SOD1;ITIH4;KNG1;FGA;SERPINA3;A1BG;AHSG;ALB;APOA1;ITIH3;APP;SERPINA4;ALDOA;ORM2;CLU;FN1 GO:0042493| response to drug NME1;MGMT;CYP2E1;SOD1;TP73;APOA1;APOA2;MDM2;TP53;HDAC4;HDAC1 GO:0043687| post-translational protein modification ITIH2;APOL1;P4HB;TF;APLP2;C3;CP;SERPIND1;SERPINA1;APOE;APOA2;APP;FN1;KNG1;FGA;AHSG;ALB;APOA1 GO:0055114| oxidation-reduction process CCS;CP;ADH1C;P4HB;CYP2E1;SOD1;PRDX1;PDIA3;GAPDHS GO:0010243| response to organic nitrogen TP53;TP73;CYP2E1 GO:0006898| receptor-mediated endocytosis CFI;IGHA1;APOL1;IGLV3-21;VTN;APOBR;JCHAIN;ALB;APOA1;IGKV1-17;HBB;HBA1;HPR;APOE GO:0006641| triglyceride metabolic process APOBR;APOE;APOA2;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling APOA4;APOE;APOA2;APOA1;ALB GO:0001895| retina homeostasis ALB;JCHAIN;PRDX1;SOD1;IGHA1;TF;KRT1 GO:0045471| response to ethanol S100A8;GSN;CYP2E1;MGMT;SOD1;TUFM;TP53 GO:0006508| proteolysis CFB;IGKV1-17;PDCD6;F2;CPN2;FCN3;IDE;MMP9;CPN1;C1R;C1QB;PDIA3;KLK1;C4B;KLKB1;CFI;C3;C1QC;C1S;DCD;F12;CPE;BRCC3;IGLV3-21 31046:[DB06728 DB06837] DB06728|Aniline KLK1;ALB;CYP2E1 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways GO:0006508| proteolysis ADAMTS5;KLK1 31047:[DB06728 DB07962] DB06728|Aniline KLK1;ALB;CYP2E1 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 31048:[DB06728 DB03861] DB06728|Aniline KLK1;ALB;CYP2E1 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;HEXB 31049:[DB06728 DB07714] DB06728|Aniline KLK1;ALB;CYP2E1 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways GO:0098869| GSR;ALB GO:0055114| oxidation-reduction process GSR;CYP2E1 31050:[DB06728 DB08083] DB06728|Aniline KLK1;ALB;CYP2E1 DB08083|2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide CA2 common genes common pathways 31051:[DB06728 DB01966] DB06728|Aniline KLK1;ALB;CYP2E1 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways GO:0002576| platelet degranulation PSAP;ALB 31052:[DB06728 DB04816] DB06728|Aniline KLK1;ALB;CYP2E1 DB04816|Dantron ALB common genes ALB common pathways GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31053:[DB06728 DB04959] DB06728|Aniline KLK1;ALB;CYP2E1 DB04959|HspE7 KRT7;UBR4 common genes common pathways 31054:[DB06728 DB05076] DB06728|Aniline KLK1;ALB;CYP2E1 DB05076|Fenretinide RBP4 common genes common pathways GO:0045471| response to ethanol RBP4;CYP2E1 31055:[DB06728 DB04846] DB06728|Aniline KLK1;ALB;CYP2E1 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ADRB2;ALB;ADRB3 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 31056:[DB06728 DB01893] DB06728|Aniline KLK1;ALB;CYP2E1 DB01893|N6-Benzyl Adenosine-5'-Diphosphate SRC common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC GO:0042493| response to drug CYP2E1;SRC 31057:[DB06728 DB08660] DB06728|Aniline KLK1;ALB;CYP2E1 DB08660|1,2,5,8-tetrahydroxyanthracene-9,10-dione CSNK2A1 common genes common pathways 31058:[DB06728 DB01698] DB06728|Aniline KLK1;ALB;CYP2E1 DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2E1;AKR1C3;CBR1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CBR1;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process AKR1C3;CYP3A4;CYP2E1;CYP2C8 GO:0009267| cellular response to starvation AKR1C3;ALB 31059:[DB06728 DB05713] DB06728|Aniline KLK1;ALB;CYP2E1 DB05713|LY-517717 F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 31060:[DB06728 DB00992] DB06728|Aniline KLK1;ALB;CYP2E1 DB00992|Methyl aminolevulinate FCGR1A common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FCGR1A 31061:[DB06728 DB03994] DB06728|Aniline KLK1;ALB;CYP2E1 DB03994|Ethanolamine ANXA3 common genes common pathways 31062:[DB06728 DB04400] DB06728|Aniline KLK1;ALB;CYP2E1 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0055114| oxidation-reduction process PAH;NOS2;PCBD1;CYP2E1;TH GO:0042493| response to drug CYP2E1;TH GO:0045471| response to ethanol CYP2E1;TH 31063:[DB06728 DB01791] DB06728|Aniline KLK1;ALB;CYP2E1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways 31064:[DB06728 DB00896] DB06728|Aniline KLK1;ALB;CYP2E1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 31065:[DB06728 DB04594] DB06728|Aniline KLK1;ALB;CYP2E1 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways 31066:[DB06728 DB00967] DB06728|Aniline KLK1;ALB;CYP2E1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP1A2;CYP2C9;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C9;CYP1A2;CYP2E1 GO:0042493| response to drug ABCB1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C9;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2;CYP2C19;CYP2D6 31067:[DB06728 DB06789] DB06728|Aniline KLK1;ALB;CYP2E1 DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A5;CYP3A4;CYP2E1 31068:[DB06728 DB03645] DB06728|Aniline KLK1;ALB;CYP2E1 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways GO:0042493| response to drug CYP2E1;ENO3 31069:[DB06728 DB11827] DB06728|Aniline KLK1;ALB;CYP2E1 DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;ABCB1;ABCG2;UGT1A1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process UGT1A1;CYP2E1;UGT2B7 GO:0017144| drug metabolic process CYP2E1;UGT1A4;UGT1A1;UGT1A9 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process UGT1A9;CYP2E1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 31070:[DB06728 DB02581] DB06728|Aniline KLK1;ALB;CYP2E1 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways GO:0045471| response to ethanol CYP2E1;IL2 GO:0043066| negative regulation of apoptotic process IL2;ALB 31071:[DB06728 DB00584] DB06728|Aniline KLK1;ALB;CYP2E1 DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006508| proteolysis KLK1;ACE GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLC22A7;SLCO1A2;SLC22A8;ALB;SLC22A6 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31072:[DB06728 DB00485] DB06728|Aniline KLK1;ALB;CYP2E1 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 31073:[DB06728 DB06599] DB06728|Aniline KLK1;ALB;CYP2E1 DB06599|Lexatumumab TNFRSF10B common genes common pathways 31074:[DB06728 DB05552] DB06728|Aniline KLK1;ALB;CYP2E1 DB05552|TG100-115 PIK3CD;PIK3CG common genes common pathways 31075:[DB06728 DB07224] DB06728|Aniline KLK1;ALB;CYP2E1 DB07224|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE CTSB common genes common pathways GO:0006508| proteolysis CTSB;KLK1 31076:[DB06728 DB07148] DB06728|Aniline KLK1;ALB;CYP2E1 DB07148|(6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one PREP common genes common pathways GO:0006508| proteolysis PREP;KLK1 31077:[DB06728 DB03132] DB06728|Aniline KLK1;ALB;CYP2E1 DB03132|3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid TPI1 common genes common pathways 31078:[DB06728 DB12070] DB06728|Aniline KLK1;ALB;CYP2E1 DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP2B6;CYP2C9;CYP3A7;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2B6;UGT1A1;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4;UGT1A3 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLC22A8;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2B6;CYP2C9;UGT1A1;CYP2D6;CYP2C19;CYP2C8;CYP3A5 GO:0015721| bile acid and bile salt transport ALB;ABCB11;SLCO1B1;SLCO1B3 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2B6;CYP2C8;CYP2C19 GO:0042493| response to drug CYP2E1;ABCB1;ABCG2;ABCC2;UGT1A1 GO:0055114| oxidation-reduction process CYP3A43;CYP3A7;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP2B6;CYP2C9 31079:[DB06728 DB05471] DB06728|Aniline KLK1;ALB;CYP2E1 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways GO:0043066| negative regulation of apoptotic process NFKB1;ALB 31080:[DB06728 DB06870] DB06728|Aniline KLK1;ALB;CYP2E1 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways 31081:[DB06728 DB07395] DB06728|Aniline KLK1;ALB;CYP2E1 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways 31082:[DB06728 DB08119] DB06728|Aniline KLK1;ALB;CYP2E1 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways GO:0006508| proteolysis CTRB1;KLK1 31083:[DB06728 DB07072] DB06728|Aniline KLK1;ALB;CYP2E1 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 31084:[DB06728 DB06705] DB06728|Aniline KLK1;ALB;CYP2E1 DB06705|Gadofosveset trisodium ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31085:[DB06728 DB08934] DB06728|Aniline KLK1;ALB;CYP2E1 DB08934|Sofosbuvir CTSA;HINT1;CMPK1;NME1;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;CYP2E1;NME1 GO:0006508| proteolysis CTSA;KLK1 31086:[DB06728 DB01640] DB06728|Aniline KLK1;ALB;CYP2E1 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways 31087:[DB06728 DB02762] DB06728|Aniline KLK1;ALB;CYP2E1 DB02762|RU79072 SRC common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process SRC;ALB 31088:[DB06728 DB04136] DB06728|Aniline KLK1;ALB;CYP2E1 DB04136|Lysophosphotidylserine F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 31089:[DB06728 DB07494] DB06728|Aniline KLK1;ALB;CYP2E1 DB07494|(3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE CHRFAM7A common genes common pathways 31090:[DB06728 DB00520] DB06728|Aniline KLK1;ALB;CYP2E1 DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLCO1B1;SLCO1B3 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31091:[DB06728 DB02988] DB06728|Aniline KLK1;ALB;CYP2E1 DB02988|Imino-Tryptophan DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;CYP2E1 31092:[DB06728 DB05708] DB06728|Aniline KLK1;ALB;CYP2E1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes CYP2E1 common pathways GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 31093:[DB06728 DB08843] DB06728|Aniline KLK1;ALB;CYP2E1 DB08843|GS 0573 SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 31094:[DB06728 DB00383] DB06728|Aniline KLK1;ALB;CYP2E1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways 31095:[DB06728 DB07613] DB06728|Aniline KLK1;ALB;CYP2E1 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways 31096:[DB06728 DB07261] DB06728|Aniline KLK1;ALB;CYP2E1 DB07261|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 31097:[DB06728 DB06849] DB06728|Aniline KLK1;ALB;CYP2E1 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways GO:0006508| proteolysis KLK1;TPSAB1 31098:[DB06728 DB00616] DB06728|Aniline KLK1;ALB;CYP2E1 DB00616|Candoxatril MME;ACE common genes common pathways GO:0006508| proteolysis KLK1;ACE;MME 31099:[DB06728 DB00180] DB06728|Aniline KLK1;ALB;CYP2E1 DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 31100:[DB06728 DB08960] DB06728|Aniline KLK1;ALB;CYP2E1 DB08960|Hexamethonium CHRNA2 common genes common pathways 31101:[DB06728 DB06147] DB06728|Aniline KLK1;ALB;CYP2E1 DB06147|Sulfathiazole CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1 31102:[DB06728 DB13136] DB06728|Aniline KLK1;ALB;CYP2E1 DB13136|Fluindione CYP2C9;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2E1;CYP3A4 31103:[DB06728 DB02950] DB06728|Aniline KLK1;ALB;CYP2E1 DB02950|Hymenialdisine CDK5;CDK1;CDK2 common genes common pathways GO:0045471| response to ethanol CDK1;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;CDK1 GO:0042493| response to drug CYP2E1;CDK1 GO:0043066| negative regulation of apoptotic process ALB;CDK1 31104:[DB06728 DB06716] DB06728|Aniline KLK1;ALB;CYP2E1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB 31105:[DB06728 DB01662] DB06728|Aniline KLK1;ALB;CYP2E1 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways GO:0006508| proteolysis KLK1;CTRB1 31106:[DB06728 DB07350] DB06728|Aniline KLK1;ALB;CYP2E1 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways 31107:[DB06728 DB07849] DB06728|Aniline KLK1;ALB;CYP2E1 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0098869| GSTP1;ALB 31108:[DB06728 DB11855] DB06728|Aniline KLK1;ALB;CYP2E1 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0042493| response to drug ABCB1;ABCG2;CYP2E1 31109:[DB06728 DB00641] DB06728|Aniline KLK1;ALB;CYP2E1 DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8;CYP2C19;CYP2B6;CYP2C9 GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP3A7;HMGCR;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;ABCC2;UGT1A1;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP2C9;CYP2B6;UGT1A1;CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP3A7;HMGCR;UGT2B7 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;UGT1A1;UGT1A3;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1A2;ABCB11;SLCO1B1;ALB GO:0045471| response to ethanol UGT1A1;HMGCR;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP2B6;CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP3A5 31110:[DB06728 DB12515] DB06728|Aniline KLK1;ALB;CYP2E1 DB12515|9-aminocamptothecin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31111:[DB06728 DB03297] DB06728|Aniline KLK1;ALB;CYP2E1 DB03297|Benzylsulfinic Acid HPN;SOD2;CMA1 common genes common pathways GO:0043066| negative regulation of apoptotic process HPN;ALB GO:0055114| oxidation-reduction process CYP2E1;SOD2 GO:0006508| proteolysis KLK1;CMA1;HPN 31112:[DB06728 DB01497] DB06728|Aniline KLK1;ALB;CYP2E1 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 31113:[DB06728 DB00264] DB06728|Aniline KLK1;ALB;CYP2E1 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0006898| receptor-mediated endocytosis ADRB2;ALB 31114:[DB06728 DB12865] DB06728|Aniline KLK1;ALB;CYP2E1 DB12865|Etelcalcetide CASR common genes common pathways 31115:[DB06728 DB07007] DB06728|Aniline KLK1;ALB;CYP2E1 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 31116:[DB06728 DB09536] DB06728|Aniline KLK1;ALB;CYP2E1 DB09536|Titanium dioxide MARCO common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;MARCO 31117:[DB06728 DB03531] DB06728|Aniline KLK1;ALB;CYP2E1 DB03531|Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;CYP2E1 31118:[DB06728 DB05253] DB06728|Aniline KLK1;ALB;CYP2E1 DB05253|Proellex PGR common genes common pathways 31119:[DB06728 DB04418] DB06728|Aniline KLK1;ALB;CYP2E1 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways 31120:[DB06728 DB00523] DB06728|Aniline KLK1;ALB;CYP2E1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0045471| response to ethanol CYP2E1;RARA GO:0043066| negative regulation of apoptotic process RARB;ALB;RARA;RARG GO:0055114| oxidation-reduction process CYP2E1;CYP26C1 GO:0043687| post-translational protein modification ALB;IGFBP3 GO:0042493| response to drug ABCB1;CYP2E1 GO:0044267| cellular protein metabolic process ALB;IGFBP3 GO:0015721| bile acid and bile salt transport ALB;RXRA 31121:[DB06728 DB00259] DB06728|Aniline KLK1;ALB;CYP2E1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0010243| response to organic nitrogen CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0018910| benzene metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 31122:[DB06728 DB00306] DB06728|Aniline KLK1;ALB;CYP2E1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug CYP2E1;GABRG3 31123:[DB06728 DB00288] DB06728|Aniline KLK1;ALB;CYP2E1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ANXA1 GO:0043066| negative regulation of apoptotic process ANXA1;ALB 31124:[DB06728 DB03623] DB06728|Aniline KLK1;ALB;CYP2E1 DB03623|9-(4-Hydroxyphenyl)-2,7-Phenanthroline MAPK10 common genes common pathways 31125:[DB06728 DB08674] DB06728|Aniline KLK1;ALB;CYP2E1 DB08674|(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways 31126:[DB06728 DB00279] DB06728|Aniline KLK1;ALB;CYP2E1 DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;SLCO1B3;SLC10A1;ALB;SLCO1C1 GO:0044267| cellular protein metabolic process TTR;ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO4A1;SLCO1B3;SLC22A8;SLCO1B1;SLCO1A2;SLCO4C1;ALB;SLCO1C1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB 31127:[DB06728 DB00156] DB06728|Aniline KLK1;ALB;CYP2E1 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways 31128:[DB06728 DB03095] DB06728|Aniline KLK1;ALB;CYP2E1 DB03095|Tetramethylammonium Ion GALE common genes common pathways 31129:[DB06728 DB04975] DB06728|Aniline KLK1;ALB;CYP2E1 DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2B6;CYP1A1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2B6;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP1A1 GO:0042493| response to drug CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2B6;CYP1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2B6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 31130:[DB06728 DB13503] DB06728|Aniline KLK1;ALB;CYP2E1 DB13503|Tyrothricin ACHE common genes common pathways 31131:[DB06728 DB09279] DB06728|Aniline KLK1;ALB;CYP2E1 DB09279|Fimasartan AGTR1 common genes common pathways 31132:[DB06728 DB03124] DB06728|Aniline KLK1;ALB;CYP2E1 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways GO:0042493| response to drug CASP3;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;CASP3 GO:0006508| proteolysis KLK1;CASP3 31133:[DB06728 DB08626] DB06728|Aniline KLK1;ALB;CYP2E1 DB08626|Thiorphan MME common genes common pathways GO:0006508| proteolysis MME;KLK1 31134:[DB06728 DB05115] DB06728|Aniline KLK1;ALB;CYP2E1 DB05115|NN344 INSR common genes common pathways 31135:[DB06728 DB08345] DB06728|Aniline KLK1;ALB;CYP2E1 DB08345|4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 31136:[DB06728 DB06042] DB06728|Aniline KLK1;ALB;CYP2E1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways 31137:[DB06728 DB01832] DB06728|Aniline KLK1;ALB;CYP2E1 DB01832|4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid FAH common genes common pathways 31138:[DB06728 DB03425] DB06728|Aniline KLK1;ALB;CYP2E1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways 31139:[DB06728 DB07809] DB06728|Aniline KLK1;ALB;CYP2E1 DB07809|4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 31140:[DB06728 DB08060] DB06728|Aniline KLK1;ALB;CYP2E1 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways 31141:[DB06728 DB05264] DB06728|Aniline KLK1;ALB;CYP2E1 DB05264|NPI 32101 CSF2RB common genes common pathways GO:0044267| cellular protein metabolic process CSF2RB;ALB 31142:[DB06728 DB01742] DB06728|Aniline KLK1;ALB;CYP2E1 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways 31143:[DB06728 DB00750] DB06728|Aniline KLK1;ALB;CYP2E1 DB00750|Prilocaine SCN5A common genes common pathways 31144:[DB06728 DB05849] DB06728|Aniline KLK1;ALB;CYP2E1 DB05849|NCX 950 ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 31145:[DB06728 DB03470] DB06728|Aniline KLK1;ALB;CYP2E1 DB03470|Trypanothione TPR common genes common pathways 31146:[DB06728 DB02541] DB06728|Aniline KLK1;ALB;CYP2E1 DB02541|4-Hydroxybutan-1-Aminium PRSS3 common genes common pathways GO:0006508| proteolysis PRSS3;KLK1 31147:[DB06728 DB08510] DB06728|Aniline KLK1;ALB;CYP2E1 DB08510|5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE IGHG2 common genes common pathways GO:0006508| proteolysis IGHG2;KLK1 31148:[DB06728 DB04445] DB06728|Aniline KLK1;ALB;CYP2E1 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;SULT2A1 31149:[DB06728 DB07964] DB06728|Aniline KLK1;ALB;CYP2E1 DB07964|(3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0006508| proteolysis KLK1;ADAM17 GO:0042493| response to drug CYP2E1;ADAM17 31150:[DB06728 DB04133] DB06728|Aniline KLK1;ALB;CYP2E1 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLC22A11 31151:[DB06728 DB12923] DB06728|Aniline KLK1;ALB;CYP2E1 DB12923|Gallopamil CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31152:[DB06728 DB04934] DB06728|Aniline KLK1;ALB;CYP2E1 DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31153:[DB06728 DB00751] DB06728|Aniline KLK1;ALB;CYP2E1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2B6 GO:0042493| response to drug ABCB1;ADRA1A;CYP2E1;HTR2A GO:0017144| drug metabolic process CYP2B6;CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2B6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 31154:[DB06728 DB01537] DB06728|Aniline KLK1;ALB;CYP2E1 DB01537|4-Bromo-2,5-dimethoxyphenethylamine HTR2C;HTR2A common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1;HTR2C 31155:[DB06728 DB03666] DB06728|Aniline KLK1;ALB;CYP2E1 DB03666|3'-Azido-3'-Deoxythymidine-5'-Monophosphate DTYMK;tmk common genes common pathways 31156:[DB06728 DB09232] DB06728|Aniline KLK1;ALB;CYP2E1 DB09232|Cilnidipine CACNA1B;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 31157:[DB06728 DB00621] DB06728|Aniline KLK1;ALB;CYP2E1 DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 31158:[DB06728 DB08972] DB06728|Aniline KLK1;ALB;CYP2E1 DB08972|Flumequine CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 31159:[DB06728 DB00765] DB06728|Aniline KLK1;ALB;CYP2E1 DB00765|Metyrosine TH common genes common pathways GO:0055114| oxidation-reduction process TH;CYP2E1 GO:0042493| response to drug CYP2E1;TH GO:0045471| response to ethanol TH;CYP2E1 31160:[DB06728 DB05824] DB06728|Aniline KLK1;ALB;CYP2E1 DB05824|CNS-5161 GRIN1 common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN1 31161:[DB06728 DB01109] DB06728|Aniline KLK1;ALB;CYP2E1 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0045471| response to ethanol FGFR2;CYP2E1 GO:0006508| proteolysis KLK1;HGF;F10 GO:0043066| negative regulation of apoptotic process FGF4;HGF;ALB GO:0002576| platelet degranulation PF4;ALB;HGF;SELP GO:0043687| post-translational protein modification ALB;SERPINC1 GO:0044267| cellular protein metabolic process SERPINC1;ALB 31162:[DB06728 DB03988] DB06728|Aniline KLK1;ALB;CYP2E1 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways GO:0045471| response to ethanol ADCYAP1;CYP2E1 31163:[DB06728 DB00805] DB06728|Aniline KLK1;ALB;CYP2E1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0055114| oxidation-reduction process MAOA;CYP2E1;CYP2D6 GO:0042493| response to drug DRD1;SLC6A4;HTR2A;CYP2E1;HTR2C;HTR2B;DRD2 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 31164:[DB06728 DB11793] DB06728|Aniline KLK1;ALB;CYP2E1 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways 31165:[DB06728 DB03316] DB06728|Aniline KLK1;ALB;CYP2E1 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways GO:0002576| platelet degranulation TGFB3;ALB 31166:[DB06728 DB06185] DB06728|Aniline KLK1;ALB;CYP2E1 DB06185|Forodesine PNP common genes common pathways GO:0042493| response to drug PNP;CYP2E1 31167:[DB06728 DB00199] DB06728|Aniline KLK1;ALB;CYP2E1 DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes ALB common pathways GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2B6;CYP3A5 GO:0042493| response to drug ABCB1;CYP1A2;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP3A5;CYP2B6 GO:0017144| drug metabolic process CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ABCB11;ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2B6 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 31168:[DB06728 DB01445] DB06728|Aniline KLK1;ALB;CYP2E1 DB01445|Bufotenine MAOA;MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOA;CYP2E1;MAOB GO:0042493| response to drug CYP2E1;MAOB 31169:[DB06728 DB00374] DB06728|Aniline KLK1;ALB;CYP2E1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 31170:[DB06728 DB08445] DB06728|Aniline KLK1;ALB;CYP2E1 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 31171:[DB06728 DB03319] DB06728|Aniline KLK1;ALB;CYP2E1 DB03319|(S)-ATPA GRIA2 common genes common pathways 31172:[DB06728 DB05875] DB06728|Aniline KLK1;ALB;CYP2E1 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0098869| ALB;PTGS2 GO:0055114| oxidation-reduction process CYP19A1;CYP2E1;PTGS2 GO:0042493| response to drug BCHE;CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 31173:[DB06728 DB12285] DB06728|Aniline KLK1;ALB;CYP2E1 DB12285|Verubecestat BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process BACE1;ALB 31174:[DB06728 DB00958] DB06728|Aniline KLK1;ALB;CYP2E1 DB00958|Carboplatin XDH;MPO;GSTT1;MT1A;MT2A;SOD1;GSTP1;GSTM1;NQO1;SLC31A1;SLC31A2;ATP7A;ATP7B;ABCG2;ABCC2 common genes common pathways GO:0001895| retina homeostasis ALB;SOD1 GO:0045471| response to ethanol GSTP1;NQO1;CYP2E1;SOD1 GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1;NQO1 GO:0098869| GSTP1;GSTT1;ALB GO:0002576| platelet degranulation ALB;SOD1 GO:0043066| negative regulation of apoptotic process NQO1;ALB;GSTP1;SOD1;MPO GO:0042493| response to drug SOD1;CYP2E1;ABCC2;ABCG2 GO:0055114| oxidation-reduction process NQO1;XDH;CYP2E1;SOD1;MPO 31175:[DB06728 DB08280] DB06728|Aniline KLK1;ALB;CYP2E1 DB08280|(1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1 GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 31176:[DB06728 DB06989] DB06728|Aniline KLK1;ALB;CYP2E1 DB06989|{4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways 31177:[DB06728 DB04880] DB06728|Aniline KLK1;ALB;CYP2E1 DB04880|Enoximone PDE3A common genes common pathways GO:0042493| response to drug PDE3A;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PDE3A 31178:[DB06728 DB12007] DB06728|Aniline KLK1;ALB;CYP2E1 DB12007|Isoflavone PPARA;PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 31179:[DB06728 DB08801] DB06728|Aniline KLK1;ALB;CYP2E1 DB08801|Dimetindene HRH1;CHRM2 common genes common pathways 31180:[DB06728 DB00947] DB06728|Aniline KLK1;ALB;CYP2E1 DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;UGT1A1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 31181:[DB06728 DB00382] DB06728|Aniline KLK1;ALB;CYP2E1 DB00382|Tacrine ACHE;BCHE;CES1;CYP1A2;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug BCHE;ABCB1;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;CYP1A2 31182:[DB06728 DB06932] DB06728|Aniline KLK1;ALB;CYP2E1 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways 31183:[DB06728 DB07724] DB06728|Aniline KLK1;ALB;CYP2E1 DB07724|Indeglitazar NCOA1;PPARA;PPARD;PPARG common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA1 GO:0042493| response to drug CYP2E1;PPARG GO:0043066| negative regulation of apoptotic process ALB;PPARD 31184:[DB06728 DB01762] DB06728|Aniline KLK1;ALB;CYP2E1 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways 31185:[DB06728 DB08899] DB06728|Aniline KLK1;ALB;CYP2E1 DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2B6;CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2D6 GO:0098869| ALB GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 31186:[DB06728 DB02089] DB06728|Aniline KLK1;ALB;CYP2E1 DB02089|CP-526423 PYGL common genes common pathways 31187:[DB06728 DB01134] DB06728|Aniline KLK1;ALB;CYP2E1 DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 31188:[DB06728 DB00527] DB06728|Aniline KLK1;ALB;CYP2E1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 GO:0002576| platelet degranulation CALM1;ALB 31189:[DB06728 DB00253] DB06728|Aniline KLK1;ALB;CYP2E1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 31190:[DB06728 DB05386] DB06728|Aniline KLK1;ALB;CYP2E1 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways GO:0044267| cellular protein metabolic process ALB;CSF2RA GO:0042493| response to drug CYP2E1;BCHE 31191:[DB06728 DB03430] DB06728|Aniline KLK1;ALB;CYP2E1 DB03430|(2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile LCTL common genes common pathways 31192:[DB06728 DB07294] DB06728|Aniline KLK1;ALB;CYP2E1 DB07294|3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid RARG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 31193:[DB06728 DB05429] DB06728|Aniline KLK1;ALB;CYP2E1 DB05429|CAT-213 CCL11 common genes common pathways 31194:[DB06728 DB07689] DB06728|Aniline KLK1;ALB;CYP2E1 DB07689|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process DHRS4L1;CYP2E1 31195:[DB06728 DB06127] DB06728|Aniline KLK1;ALB;CYP2E1 DB06127|Bisegliptin DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 31196:[DB06728 DB07574] DB06728|Aniline KLK1;ALB;CYP2E1 DB07574|2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE STMN4;TUBB2B;TUBA1A;TUBA1C;TUBA1B common genes common pathways 31197:[DB06728 DB01323] DB06728|Aniline KLK1;ALB;CYP2E1 DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0042493| response to drug CYP2E1;ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 31198:[DB06728 DB09051] DB06728|Aniline KLK1;ALB;CYP2E1 DB09051|Elosulfase alfa GALNS common genes common pathways 31199:[DB06728 DB06781] DB06728|Aniline KLK1;ALB;CYP2E1 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31200:[DB06728 DB01615] DB06728|Aniline KLK1;ALB;CYP2E1 DB01615|Aceprometazine HRH1 common genes common pathways 31201:[DB06728 DB00939] DB06728|Aniline KLK1;ALB;CYP2E1 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0043252| sodium-independent organic anion transport SLC22A6;SLCO1C1;ALB GO:0098869| ALB;PTGS1;PTGS2 GO:0015721| bile acid and bile salt transport SLCO1C1;ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process ALOX5;PTGS1;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 31202:[DB06728 DB02800] DB06728|Aniline KLK1;ALB;CYP2E1 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways 31203:[DB06728 DB04931] DB06728|Aniline KLK1;ALB;CYP2E1 DB04931|Afamelanotide MC1R common genes common pathways 31204:[DB06728 DB09151] DB06728|Aniline KLK1;ALB;CYP2E1 DB09151|Flutemetamol (18F) APP common genes common pathways GO:0002576| platelet degranulation ALB;APP GO:0043687| post-translational protein modification ALB;APP GO:0044267| cellular protein metabolic process ALB;APP 31205:[DB06728 DB05945] DB06728|Aniline KLK1;ALB;CYP2E1 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways 31206:[DB06728 DB07815] DB06728|Aniline KLK1;ALB;CYP2E1 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways 31207:[DB06728 DB11131] DB06728|Aniline KLK1;ALB;CYP2E1 DB11131|Capsicum oleoresin TRPV1 common genes common pathways GO:0010243| response to organic nitrogen TRPV1;CYP2E1 31208:[DB06728 DB03478] DB06728|Aniline KLK1;ALB;CYP2E1 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways 31209:[DB06728 DB01481] DB06728|Aniline KLK1;ALB;CYP2E1 DB01481|1-Testosterone AR common genes common pathways 31210:[DB06728 DB01892] DB06728|Aniline KLK1;ALB;CYP2E1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP2E1;NR1I2 GO:0098869| ALB;PTGS1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0055114| oxidation-reduction process CYP2E1;PTGS1;ALOX5 GO:0042493| response to drug CYP2E1;ABCC2 GO:0006805| xenobiotic metabolic process NR1I2;CYP2E1;PTGS1 31211:[DB06728 DB06823] DB06728|Aniline KLK1;ALB;CYP2E1 DB06823|Tiopronin MPO common genes common pathways GO:0043066| negative regulation of apoptotic process MPO;ALB GO:0055114| oxidation-reduction process CYP2E1;MPO 31212:[DB06728 DB00369] DB06728|Aniline KLK1;ALB;CYP2E1 DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 31213:[DB06728 DB01141] DB06728|Aniline KLK1;ALB;CYP2E1 DB01141|Micafungin COMT;ARSA common genes common pathways GO:0042493| response to drug CYP2E1;COMT GO:0043687| post-translational protein modification ALB;ARSA 31214:[DB06728 DB07183] DB06728|Aniline KLK1;ALB;CYP2E1 DB07183|N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 31215:[DB06728 DB06804] DB06728|Aniline KLK1;ALB;CYP2E1 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0098869| ALB;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 31216:[DB06728 DB03968] DB06728|Aniline KLK1;ALB;CYP2E1 DB03968|1-Methyl-2-Oxy-5,5-Dimethyl Pyrrolidine REN common genes common pathways GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug REN;CYP2E1 31217:[DB06728 DB08678] DB06728|Aniline KLK1;ALB;CYP2E1 DB08678|(4-ETHYLPHENYL)SULFAMIC ACID PTPRB common genes common pathways 31218:[DB06728 DB01939] DB06728|Aniline KLK1;ALB;CYP2E1 DB01939|5-Amidino-Benzimidazole PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 31219:[DB06728 DB12131] DB06728|Aniline KLK1;ALB;CYP2E1 DB12131|Vinpocetine CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 31220:[DB06728 DB13154] DB06728|Aniline KLK1;ALB;CYP2E1 DB13154|Parachlorophenol SCN4A;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B3 GO:0043252| sodium-independent organic anion transport SLCO1B3;ALB 31221:[DB06728 DB00826] DB06728|Aniline KLK1;ALB;CYP2E1 DB00826|Natamycin CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 31222:[DB06728 DB04820] DB06728|Aniline KLK1;ALB;CYP2E1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0042493| response to drug COMT;MAOB;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;MAOA;MAOB GO:0045471| response to ethanol MAOB;CYP2E1 31223:[DB06728 DB06515] DB06728|Aniline KLK1;ALB;CYP2E1 DB06515|Resiniferatoxin TRPV1 common genes common pathways GO:0010243| response to organic nitrogen TRPV1;CYP2E1 31224:[DB06728 DB07659] DB06728|Aniline KLK1;ALB;CYP2E1 DB07659|AC-(D)PHE-PRO-BOROHOMOLYS-OH F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 31225:[DB06728 DB07182] DB06728|Aniline KLK1;ALB;CYP2E1 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways GO:0006508| proteolysis KLK1;CPB1 31226:[DB06728 DB02008] DB06728|Aniline KLK1;ALB;CYP2E1 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways 31227:[DB06728 DB06754] DB06728|Aniline KLK1;ALB;CYP2E1 DB06754|Danaparoid SERPINC1 common genes common pathways GO:0043687| post-translational protein modification ALB;SERPINC1 GO:0044267| cellular protein metabolic process ALB;SERPINC1 31228:[DB06728 DB04474] DB06728|Aniline KLK1;ALB;CYP2E1 DB04474|1-Anilino-8-Naphthalene Sulfonate murA;S100A7;FABP4;TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 31229:[DB06728 DB07537] DB06728|Aniline KLK1;ALB;CYP2E1 DB07537|N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 31230:[DB06728 DB07486] DB06728|Aniline KLK1;ALB;CYP2E1 DB07486|3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline ITGAL common genes common pathways 31231:[DB06728 DB13346] DB06728|Aniline KLK1;ALB;CYP2E1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 31232:[DB06728 DB08129] DB06728|Aniline KLK1;ALB;CYP2E1 DB08129|(1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol PNMT common genes common pathways 31233:[DB06728 DB00099] DB06728|Aniline KLK1;ALB;CYP2E1 DB00099|Filgrastim CSF3R;ELANE common genes common pathways GO:0006508| proteolysis KLK1;ELANE 31234:[DB06728 DB11742] DB06728|Aniline KLK1;ALB;CYP2E1 DB11742|Ebastine CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31235:[DB06728 DB04920] DB06728|Aniline KLK1;ALB;CYP2E1 DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes CYP2E1 common pathways GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0010193| response to ozone CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;BCHE GO:0010243| response to organic nitrogen CYP2E1 31236:[DB06728 DB06742] DB06728|Aniline KLK1;ALB;CYP2E1 DB06742|Ambroxol CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 31237:[DB06728 DB04326] DB06728|Aniline KLK1;ALB;CYP2E1 DB04326|Dihydroxyacetone phosphate ALDOA;TPI1;ALDOB;fucA common genes common pathways GO:0002576| platelet degranulation ALB;ALDOA 31238:[DB06728 DB02216] DB06728|Aniline KLK1;ALB;CYP2E1 DB02216|S-Methylcysteine CTSD;MGMT;FABP1 common genes common pathways GO:0098869| FABP1;ALB GO:0042493| response to drug MGMT;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;FABP1;MGMT GO:0006508| proteolysis KLK1;CTSD GO:0045471| response to ethanol CYP2E1;MGMT 31239:[DB06728 DB03546] DB06728|Aniline KLK1;ALB;CYP2E1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 31240:[DB06728 DB00325] DB06728|Aniline KLK1;ALB;CYP2E1 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 31241:[DB06728 DB06218] DB06728|Aniline KLK1;ALB;CYP2E1 DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C9;CYP2E1;CYP3A4 31242:[DB06728 DB00287] DB06728|Aniline KLK1;ALB;CYP2E1 DB00287|Travoprost PTGFR common genes common pathways GO:0043066| negative regulation of apoptotic process PTGFR;ALB 31243:[DB06728 DB01006] DB06728|Aniline KLK1;ALB;CYP2E1 DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2A6;CYP19A1 31244:[DB06728 DB01378] DB06728|Aniline KLK1;ALB;CYP2E1 DB01378|Magnesium cation ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;CYP2E1 31245:[DB06728 DB13931] DB06728|Aniline KLK1;ALB;CYP2E1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways 31246:[DB06728 DB04837] DB06728|Aniline KLK1;ALB;CYP2E1 DB04837|Clofedanol HRH1 common genes common pathways 31247:[DB06728 DB05161] DB06728|Aniline KLK1;ALB;CYP2E1 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0006508| proteolysis KLK1;PRTN3;ELANE GO:0043066| negative regulation of apoptotic process MPO;ALB GO:0055114| oxidation-reduction process CYP2E1;MPO 31248:[DB06728 DB07692] DB06728|Aniline KLK1;ALB;CYP2E1 DB07692|1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine PKM common genes common pathways 31249:[DB06728 DB00179] DB06728|Aniline KLK1;ALB;CYP2E1 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2J2 GO:0055114| oxidation-reduction process ALOX5;CYP2J2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2J2;CYP2E1 31250:[DB06728 DB08950] DB06728|Aniline KLK1;ALB;CYP2E1 DB08950|Indoramin ADRA1A common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A 31251:[DB06728 DB07879] DB06728|Aniline KLK1;ALB;CYP2E1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0042493| response to drug CYP2E1;HDAC4 31252:[DB06728 DB07453] DB06728|Aniline KLK1;ALB;CYP2E1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 31253:[DB06728 DB02179] DB06728|Aniline KLK1;ALB;CYP2E1 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 31254:[DB06728 DB03747] DB06728|Aniline KLK1;ALB;CYP2E1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways GO:0044267| cellular protein metabolic process ALB;HEXB 31255:[DB06728 DB06819] DB06728|Aniline KLK1;ALB;CYP2E1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 31256:[DB06728 DB07668] DB06728|Aniline KLK1;ALB;CYP2E1 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways GO:0006508| proteolysis CTRB1;KLK1 31257:[DB06728 DB07383] DB06728|Aniline KLK1;ALB;CYP2E1 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways GO:0006508| proteolysis KLK1;CTRB1 31258:[DB06728 DB08865] DB06728|Aniline KLK1;ALB;CYP2E1 DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5;CYP2B6 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP2B6;CYP3A5 GO:0017144| drug metabolic process CYP2B6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2B6;CYP3A5;CYP3A7;CYP2E1;CYP3A4;CYP3A43 31259:[DB06728 DB02611] DB06728|Aniline KLK1;ALB;CYP2E1 DB02611|Balanol Analog 1 PRKACA common genes common pathways 31260:[DB06728 DB05304] DB06728|Aniline KLK1;ALB;CYP2E1 DB05304|WX-G250 CA9;IL2 common genes common pathways GO:0045471| response to ethanol IL2;CYP2E1 GO:0042493| response to drug CA9;CYP2E1 GO:0043066| negative regulation of apoptotic process IL2;ALB 31261:[DB06728 DB04885] DB06728|Aniline KLK1;ALB;CYP2E1 DB04885|Cilansetron HTR3A common genes common pathways GO:0045471| response to ethanol CYP2E1;HTR3A 31262:[DB06728 DB00419] DB06728|Aniline KLK1;ALB;CYP2E1 DB00419|Miglustat UGCG common genes common pathways 31263:[DB06728 DB14528] DB06728|Aniline KLK1;ALB;CYP2E1 DB14528|Chromium gluconate CYB5A;TF common genes common pathways GO:0002576| platelet degranulation ALB;TF GO:0055114| oxidation-reduction process CYP2E1;CYB5A GO:0043687| post-translational protein modification ALB;TF GO:0044267| cellular protein metabolic process TF;ALB GO:0001895| retina homeostasis ALB;TF 31264:[DB06728 DB00602] DB06728|Aniline KLK1;ALB;CYP2E1 DB00602|Ivermectin GLRA3;GABRB3;CYP3A4;ABCB1;ABCC1;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1;ABCG2;ABCC2;ABCC1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 31265:[DB06728 DB01763] DB06728|Aniline KLK1;ALB;CYP2E1 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NNT 31266:[DB06728 DB00155] DB06728|Aniline KLK1;ALB;CYP2E1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0055114| oxidation-reduction process CYP2E1;NOS1;NOS2;NOS3 GO:0042493| response to drug OTC;CYP2E1 GO:0043066| negative regulation of apoptotic process DDAH2;ALB 31267:[DB06728 DB07096] DB06728|Aniline KLK1;ALB;CYP2E1 DB07096|6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE PARP1 common genes common pathways 31268:[DB06728 DB07272] DB06728|Aniline KLK1;ALB;CYP2E1 DB07272|N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MAPK8IP1;MAPK8 31269:[DB06728 DB08813] DB06728|Aniline KLK1;ALB;CYP2E1 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0042493| response to drug MYC;FOS;CYP2E1 GO:0043687| post-translational protein modification SERPINC1;ALB GO:0002576| platelet degranulation SELP;ALB GO:0043066| negative regulation of apoptotic process MYC;ALB GO:0044267| cellular protein metabolic process ALB;SERPINC1 31270:[DB06728 DB09082] DB06728|Aniline KLK1;ALB;CYP2E1 DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 31271:[DB06728 DB01091] DB06728|Aniline KLK1;ALB;CYP2E1 DB01091|Butenafine SQLE common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;SQLE 31272:[DB06728 DB07003] DB06728|Aniline KLK1;ALB;CYP2E1 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 31273:[DB06728 DB00055] DB06728|Aniline KLK1;ALB;CYP2E1 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0055114| oxidation-reduction process F8;CP;CYP2E1 GO:0043687| post-translational protein modification F5;ALB;CP GO:0002576| platelet degranulation SERPINE1;PROS1;F5;ALB;F8;PF4 GO:0044267| cellular protein metabolic process CP;ALB;F2;F5 31274:[DB06728 DB01359] DB06728|Aniline KLK1;ALB;CYP2E1 DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0002576| platelet degranulation ORM1;ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0042493| response to drug HTR1B;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0045471| response to ethanol HTR1B;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 31275:[DB06728 DB00281] DB06728|Aniline KLK1;ALB;CYP2E1 DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C18;CYP2C9;CYP2B6;CYP3A5;CYP2C8;CYP2D6 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0019373| epoxygenase P450 pathway CYP2C18;CYP2E1;CYP2A6;CYP1A2;CYP2C8;CYP2C9;CYP2B6 GO:0002576| platelet degranulation ORM1;ORM2;ALB GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2C18;CYP2A6;CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C8;CYP2D6;CYP3A5;CYP2B6;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2C8;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6;CYP1A2;CYP2C9;CYP2B6;CYP2C8;CYP2D6 31276:[DB06728 DB12340] DB06728|Aniline KLK1;ALB;CYP2E1 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways GO:0045471| response to ethanol BAD;CYP2E1 GO:0043066| negative regulation of apoptotic process BCL2;BCL2L2;ALB GO:0042493| response to drug BCL2;BAD;CYP2E1 31277:[DB06728 DB04606] DB06728|Aniline KLK1;ALB;CYP2E1 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0006508| proteolysis F7;KLK1 31278:[DB06728 DB00524] DB06728|Aniline KLK1;ALB;CYP2E1 DB00524|Metolazone SLC12A3 common genes common pathways 31279:[DB06728 DB04890] DB06728|Aniline KLK1;ALB;CYP2E1 DB04890|Bepotastine HRH1 common genes common pathways 31280:[DB06728 DB03661] DB06728|Aniline KLK1;ALB;CYP2E1 DB03661|Cysteinesulfonic Acid CTSL;def;GLIPR2;def;fabH;PTPN1;CDC25B common genes common pathways GO:0006508| proteolysis KLK1;CTSL 31281:[DB06728 DB07992] DB06728|Aniline KLK1;ALB;CYP2E1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 31282:[DB06728 DB03101] DB06728|Aniline KLK1;ALB;CYP2E1 DB03101|Ribose-1-Phosphate PNP common genes common pathways GO:0042493| response to drug PNP;CYP2E1 31283:[DB06728 DB08055] DB06728|Aniline KLK1;ALB;CYP2E1 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0042493| response to drug LCK;CYP2E1 31284:[DB06728 DB04884] DB06728|Aniline KLK1;ALB;CYP2E1 DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;HTR1B;HTR2C GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol CYP2E1;HTR1B GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 31285:[DB06728 DB13981] DB06728|Aniline KLK1;ALB;CYP2E1 DB13981|Nomegestrol acetate CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 31286:[DB06728 DB01776] DB06728|Aniline KLK1;ALB;CYP2E1 DB01776|M-Cresol INS common genes common pathways GO:0044267| cellular protein metabolic process INS;ALB 31287:[DB06728 DB03594] DB06728|Aniline KLK1;ALB;CYP2E1 DB03594|1,2,4-Triazole CA2 common genes common pathways 31288:[DB06728 DB09017] DB06728|Aniline KLK1;ALB;CYP2E1 DB09017|Brotizolam CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 31289:[DB06728 DB09087] DB06728|Aniline KLK1;ALB;CYP2E1 DB09087|Potassium alum ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB 31290:[DB06728 DB09121] DB06728|Aniline KLK1;ALB;CYP2E1 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug ADCY1;CYP2E1 31291:[DB06728 DB07342] DB06728|Aniline KLK1;ALB;CYP2E1 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP2E1 31292:[DB06728 DB04377] DB06728|Aniline KLK1;ALB;CYP2E1 DB04377|Meglutol HMGCR common genes common pathways GO:0045471| response to ethanol CYP2E1;HMGCR GO:0008202| steroid metabolic process HMGCR;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;HMGCR GO:0043066| negative regulation of apoptotic process HMGCR;ALB 31293:[DB06728 DB08206] DB06728|Aniline KLK1;ALB;CYP2E1 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 31294:[DB06728 DB03010] DB06728|Aniline KLK1;ALB;CYP2E1 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0002576| platelet degranulation ALB;TUBA4A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 31295:[DB06728 DB02147] DB06728|Aniline KLK1;ALB;CYP2E1 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways GO:0044267| cellular protein metabolic process C3;ALB GO:0043687| post-translational protein modification ALB;C3 GO:0006508| proteolysis C3;KLK1 31296:[DB06728 DB04405] DB06728|Aniline KLK1;ALB;CYP2E1 DB04405|2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid MMP12 common genes common pathways GO:0006508| proteolysis KLK1;MMP12 31297:[DB06728 DB04106] DB06728|Aniline KLK1;ALB;CYP2E1 DB04106|Fotemustine TXNRD1 common genes common pathways GO:0098869| ALB;TXNRD1 GO:0055114| oxidation-reduction process CYP2E1;TXNRD1 31298:[DB06728 DB03042] DB06728|Aniline KLK1;ALB;CYP2E1 DB03042|5-Phosphoarabinonic Acid GPI common genes common pathways 31299:[DB06728 DB00032] DB06728|Aniline KLK1;ALB;CYP2E1 DB00032|Menotropins FSHR;LHCGR common genes common pathways 31300:[DB06728 DB03104] DB06728|Aniline KLK1;ALB;CYP2E1 DB03104|RU82129 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC GO:0042493| response to drug SRC;CYP2E1 31301:[DB06728 DB01672] DB06728|Aniline KLK1;ALB;CYP2E1 DB01672|2,3-Dihydroxy-Benzoic Acid LCN2 common genes common pathways 31302:[DB06728 DB00323] DB06728|Aniline KLK1;ALB;CYP2E1 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0042493| response to drug CYP2E1;COMT GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 31303:[DB06728 DB00924] DB06728|Aniline KLK1;ALB;CYP2E1 DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0042493| response to drug HTR2A;CYP2E1;CYP1A2;UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 31304:[DB06728 DB11652] DB06728|Aniline KLK1;ALB;CYP2E1 DB11652|Tucatinib ERBB2 common genes common pathways 31305:[DB06728 DB02141] DB06728|Aniline KLK1;ALB;CYP2E1 DB02141|S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS3 31306:[DB06728 DB01591] DB06728|Aniline KLK1;ALB;CYP2E1 DB01591|Solifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31307:[DB06728 DB08615] DB06728|Aniline KLK1;ALB;CYP2E1 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways 31308:[DB06728 DB13158] DB06728|Aniline KLK1;ALB;CYP2E1 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 31309:[DB06728 DB08893] DB06728|Aniline KLK1;ALB;CYP2E1 DB08893|Mirabegron ADRB3;CYP3A4;CYP2D6;BCHE;ALB;ORM1;ABCB1;SLCO1A2 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB;ADRB3 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0042493| response to drug ABCB1;BCHE;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;ORM1 31310:[DB06728 DB04112] DB06728|Aniline KLK1;ALB;CYP2E1 DB04112|1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide PLA2G2A common genes common pathways 31311:[DB06728 DB02097] DB06728|Aniline KLK1;ALB;CYP2E1 DB02097|Cytidine UCK2 common genes common pathways 31312:[DB06728 DB14042] DB06728|Aniline KLK1;ALB;CYP2E1 DB14042|Galcanezumab CALCA;CALCB common genes common pathways 31313:[DB06728 DB05416] DB06728|Aniline KLK1;ALB;CYP2E1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PPARD 31314:[DB06728 DB05993] DB06728|Aniline KLK1;ALB;CYP2E1 DB05993|PRX-07034 HTR6 common genes common pathways 31315:[DB06728 DB13914] DB06728|Aniline KLK1;ALB;CYP2E1 DB13914|Volixibat SLC10A2 common genes common pathways GO:0015721| bile acid and bile salt transport SLC10A2;ALB 31316:[DB06728 DB03317] DB06728|Aniline KLK1;ALB;CYP2E1 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1;CYCS 31317:[DB06728 DB04027] DB06728|Aniline KLK1;ALB;CYP2E1 DB04027|D-Arginine CKM common genes common pathways 31318:[DB06728 DB06433] DB06728|Aniline KLK1;ALB;CYP2E1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0055114| oxidation-reduction process RRM1;CYP2E1 31319:[DB06728 DB04516] DB06728|Aniline KLK1;ALB;CYP2E1 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways 31320:[DB06728 DB00548] DB06728|Aniline KLK1;ALB;CYP2E1 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0042493| response to drug CYP2E1;SRD5A2 GO:0055114| oxidation-reduction process TYR;CYP2E1;SRD5A2;AKR1D1 GO:0008202| steroid metabolic process AKR1D1;SRD5A2;CYP2E1 31321:[DB06728 DB03109] DB06728|Aniline KLK1;ALB;CYP2E1 DB03109|N-Acetyl-D-Allosamine CHIT1 common genes common pathways 31322:[DB06728 DB06727] DB06728|Aniline KLK1;ALB;CYP2E1 DB06727|Sparteine CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 31323:[DB06728 DB00406] DB06728|Aniline KLK1;ALB;CYP2E1 DB00406|Gentian violet cation SLC22A1 common genes common pathways 31324:[DB06728 DB09401] DB06728|Aniline KLK1;ALB;CYP2E1 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0042493| response to drug CYP2E1;BCL2 GO:0043066| negative regulation of apoptotic process ALB;BCL2L1;BCL2;MCL1 31325:[DB06728 DB01818] DB06728|Aniline KLK1;ALB;CYP2E1 DB01818|O3-Sulfonylgalactose MBL2 common genes common pathways GO:0006508| proteolysis KLK1;MBL2 31326:[DB06728 DB05309] DB06728|Aniline KLK1;ALB;CYP2E1 DB05309|TP-508 FGF4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;FGF4 31327:[DB06728 DB03621] DB06728|Aniline KLK1;ALB;CYP2E1 DB03621|L-709,587 FKBP1A common genes common pathways 31328:[DB06728 DB12212] DB06728|Aniline KLK1;ALB;CYP2E1 DB12212|Landiolol CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 31329:[DB06728 DB06929] DB06728|Aniline KLK1;ALB;CYP2E1 DB06929|1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 31330:[DB06728 DB05050] DB06728|Aniline KLK1;ALB;CYP2E1 DB05050|ADL5859 OPRD1 common genes common pathways 31331:[DB06728 DB07348] DB06728|Aniline KLK1;ALB;CYP2E1 DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31332:[DB06728 DB00929] DB06728|Aniline KLK1;ALB;CYP2E1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways 31333:[DB06728 DB01270] DB06728|Aniline KLK1;ALB;CYP2E1 DB01270|Ranibizumab VEGFA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;VEGFA GO:0002576| platelet degranulation ALB;VEGFA 31334:[DB06728 DB00799] DB06728|Aniline KLK1;ALB;CYP2E1 DB00799|Tazarotene RARA;RXRB;RARG;RARB;CYP2C8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8 GO:0045471| response to ethanol CYP2E1;RARA GO:0017144| drug metabolic process CYP2C8;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;RARB;RARG;RARA GO:0055114| oxidation-reduction process CYP2E1;CYP2C8 31335:[DB06728 DB01581] DB06728|Aniline KLK1;ALB;CYP2E1 DB01581|Sulfamerazine ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31336:[DB06728 DB07246] DB06728|Aniline KLK1;ALB;CYP2E1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways GO:0006508| proteolysis MMP9;KLK1 GO:0043066| negative regulation of apoptotic process ALB;MMP9 31337:[DB06728 DB13385] DB06728|Aniline KLK1;ALB;CYP2E1 DB13385|Dihydroergocryptine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 31338:[DB06728 DB07474] DB06728|Aniline KLK1;ALB;CYP2E1 DB07474|3-[5-(1H-IMIDAZOL-1-YL)-7-METHYL-1H-BENZIMIDAZOL-2-YL]-4-[(PYRIDIN-2-YLMETHYL)AMINO]PYRIDIN-2(1H)-ONE IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IGF1R 31339:[DB06728 DB08810] DB06728|Aniline KLK1;ALB;CYP2E1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1 31340:[DB06728 DB09033] DB06728|Aniline KLK1;ALB;CYP2E1 DB09033|Vedolizumab ITGA4;ITGB7 common genes common pathways 31341:[DB06728 DB01000] DB06728|Aniline KLK1;ALB;CYP2E1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 31342:[DB06728 DB06154] DB06728|Aniline KLK1;ALB;CYP2E1 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBB;HBA1 GO:0055114| oxidation-reduction process NOS3;CYP2E1;ALDH2 GO:0098869| ALB;HBB;HBA1 31343:[DB06728 DB00847] DB06728|Aniline KLK1;ALB;CYP2E1 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0042493| response to drug SST;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;MPO GO:0010243| response to organic nitrogen SST;CYP2E1 31344:[DB06728 DB07029] DB06728|Aniline KLK1;ALB;CYP2E1 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 31345:[DB06728 DB06939] DB06728|Aniline KLK1;ALB;CYP2E1 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 31346:[DB06728 DB06162] DB06728|Aniline KLK1;ALB;CYP2E1 DB06162|Lumiliximab FCER2 common genes common pathways 31347:[DB06728 DB04270] DB06728|Aniline KLK1;ALB;CYP2E1 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 31348:[DB06728 DB08186] DB06728|Aniline KLK1;ALB;CYP2E1 DB08186|(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE KAT2B common genes common pathways 31349:[DB06728 DB06268] DB06728|Aniline KLK1;ALB;CYP2E1 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways GO:0043066| negative regulation of apoptotic process EDNRB;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2C19 GO:0008202| steroid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 31350:[DB06728 DB06097] DB06728|Aniline KLK1;ALB;CYP2E1 DB06097|GSK-923295 CENPE common genes common pathways 31351:[DB06728 DB09234] DB06728|Aniline KLK1;ALB;CYP2E1 DB09234|Darodipine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 31352:[DB06728 DB09459] DB06728|Aniline KLK1;ALB;CYP2E1 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HIF1AN 31353:[DB06728 DB08200] DB06728|Aniline KLK1;ALB;CYP2E1 DB08200|(1R)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 31354:[DB06728 DB08916] DB06728|Aniline KLK1;ALB;CYP2E1 DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 GO:0043066| negative regulation of apoptotic process ERBB4;EGFR;ALB 31355:[DB06728 DB05787] DB06728|Aniline KLK1;ALB;CYP2E1 DB05787|LM-609 ITGB3 common genes common pathways GO:0002576| platelet degranulation ALB;ITGB3 31356:[DB06728 DB08884] DB06728|Aniline KLK1;ALB;CYP2E1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 GO:0015721| bile acid and bile salt transport ALB;ABCC3;SLCO1B3;SLCO1B1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0055114| oxidation-reduction process ABCC4;CYP2E1 GO:0042493| response to drug ABCC4;CYP2E1;ABCC2 31357:[DB06728 DB12712] DB06728|Aniline KLK1;ALB;CYP2E1 DB12712|Pilsicainide ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;ABCB11 31358:[DB06728 DB12961] DB06728|Aniline KLK1;ALB;CYP2E1 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways 31359:[DB06728 DB05458] DB06728|Aniline KLK1;ALB;CYP2E1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways GO:0045471| response to ethanol CYP2E1;CHRNB2 31360:[DB06728 DB05109] DB06728|Aniline KLK1;ALB;CYP2E1 DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes CYP2E1 common pathways GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0045471| response to ethanol CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;PTGS1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1;PTGS1 GO:0010243| response to organic nitrogen CYP2E1 31361:[DB06728 DB05190] DB06728|Aniline KLK1;ALB;CYP2E1 DB05190|XL281 BRAF;RAF1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BRAF;RAF1 31362:[DB06728 DB08609] DB06728|Aniline KLK1;ALB;CYP2E1 DB08609|(2R)-N-{4-[Ethyl(phenyl)sulfamoyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide PDK2 common genes common pathways 31363:[DB06728 DB01437] DB06728|Aniline KLK1;ALB;CYP2E1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP11A1 GO:0042493| response to drug CYP2E1;GABRG3 GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP11A1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 31364:[DB06728 DB06778] DB06728|Aniline KLK1;ALB;CYP2E1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes ALB common pathways GO:0001895| retina homeostasis SOD1;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0045471| response to ethanol MAOB;SOD1;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0044267| cellular protein metabolic process ALB;CP GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB;CP GO:0055114| oxidation-reduction process MT-CO1;MAOB;PAH;CP;TYR;LOX;MAOA;CYP2E1;SOD1 GO:0042493| response to drug MAOB;SOD1;CYP2E1;LOX GO:0043066| negative regulation of apoptotic process ALB;SOD1 GO:0002576| platelet degranulation SOD1;ALB 31365:[DB06728 DB01038] DB06728|Aniline KLK1;ALB;CYP2E1 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0042493| response to drug DRD1;CYP2E1;DRD2 31366:[DB06728 DB06204] DB06728|Aniline KLK1;ALB;CYP2E1 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6;CYP2C19;CYP2C9;UGT1A9 GO:0045471| response to ethanol OPRM1;CYP2E1;HTR3A;OPRK1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C19;UGT1A9;CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2C9;UGT2B7;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;CYP2D6;CYP2C9 GO:0042493| response to drug CYP2E1;SLC6A4;SLC6A2 31367:[DB06728 DB09028] DB06728|Aniline KLK1;ALB;CYP2E1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0045471| response to ethanol CHRNB2;CYP2E1 31368:[DB06728 DB08234] DB06728|Aniline KLK1;ALB;CYP2E1 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 31369:[DB06728 DB00744] DB06728|Aniline KLK1;ALB;CYP2E1 DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;PTGS1;CYP2C9;UGT1A9 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2E1;CYP1A2;PTGS1;ALOX5 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2C9;UGT1A9;CYP2E1;CYP3A4;CYP1A2 GO:0098869| ALB;PTGS1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 31370:[DB06728 DB05777] DB06728|Aniline KLK1;ALB;CYP2E1 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways GO:0002576| platelet degranulation ALB;F5 GO:0043687| post-translational protein modification F5;ALB GO:0044267| cellular protein metabolic process F2;F5;ALB GO:0006508| proteolysis F2;KLK1 31371:[DB06728 DB00452] DB06728|Aniline KLK1;ALB;CYP2E1 DB00452|Framycetin rpsL;CXCR4 common genes common pathways 31372:[DB06728 DB04638] DB06728|Aniline KLK1;ALB;CYP2E1 DB04638|2,5-DI-(TERT-BUTYL)-1,4,BENZOHYDROQUINONE ATP2A1 common genes common pathways GO:0051659| maintenance of mitochondrion location ALB;ATP2A1 31373:[DB06728 DB03351] DB06728|Aniline KLK1;ALB;CYP2E1 DB03351|Sri-9439 DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 31374:[DB06728 DB00937] DB06728|Aniline KLK1;ALB;CYP2E1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0042493| response to drug CYP2E1;SLC6A3;SLC6A2 31375:[DB06728 DB01199] DB06728|Aniline KLK1;ALB;CYP2E1 DB01199|Tubocurarine CHRNA2;HTR3A;ACHE;CHRNA7;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0045471| response to ethanol HTR3A;CYP2E1 GO:0042493| response to drug BCHE;CYP2E1 31376:[DB06728 DB13191] DB06728|Aniline KLK1;ALB;CYP2E1 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways 31377:[DB06728 DB09067] DB06728|Aniline KLK1;ALB;CYP2E1 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways 31378:[DB06728 DB08605] DB06728|Aniline KLK1;ALB;CYP2E1 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DECR1 31379:[DB06728 DB05934] DB06728|Aniline KLK1;ALB;CYP2E1 DB05934|CTCE-0214 CXCL12 common genes common pathways 31380:[DB06728 DB06186] DB06728|Aniline KLK1;ALB;CYP2E1 DB06186|Ipilimumab CTLA4 common genes common pathways 31381:[DB06728 DB06408] DB06728|Aniline KLK1;ALB;CYP2E1 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0055114| oxidation-reduction process IMPDH1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;NT5C2 GO:0006898| receptor-mediated endocytosis ALB;ENPP1 31382:[DB06728 DB00247] DB06728|Aniline KLK1;ALB;CYP2E1 DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;HTR2A;HTR2C;HTR2B;HTR1B GO:0045471| response to ethanol CYP2E1;HTR1B GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31383:[DB06728 DB03515] DB06728|Aniline KLK1;ALB;CYP2E1 DB03515|Equilenin CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31384:[DB06728 DB03126] DB06728|Aniline KLK1;ALB;CYP2E1 DB03126|Mant-Adp MYH14 common genes common pathways 31385:[DB06728 DB05260] DB06728|Aniline KLK1;ALB;CYP2E1 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0043687| post-translational protein modification ALB;TF GO:0055114| oxidation-reduction process CYP2E1;RRM2 GO:0002576| platelet degranulation TF;ALB GO:0044267| cellular protein metabolic process ALB;TF GO:0001895| retina homeostasis ALB;TF GO:0006898| receptor-mediated endocytosis TFR2;TFRC;ALB 31386:[DB06728 DB04977] DB06728|Aniline KLK1;ALB;CYP2E1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes CYP2E1 common pathways GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2E1;CYP4A11 GO:0042493| response to drug CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP4A11 GO:0010193| response to ozone CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6 GO:0008202| steroid metabolic process CYP2A6;CYP2E1;CYP3A4 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 31387:[DB06728 DB01239] DB06728|Aniline KLK1;ALB;CYP2E1 DB01239|Chlorprothixene DRD2;DRD1;DRD3;HTR2A;HTR2B;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ABCB1 common genes common pathways GO:0042493| response to drug DRD3;DRD2;ABCB1;HTR2B;HTR2C;HTR2A;CYP2E1;DRD1 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0045471| response to ethanol CYP2E1;DRD3;DRD2 31388:[DB06728 DB07987] DB06728|Aniline KLK1;ALB;CYP2E1 DB07987|[2-(5-MERCAPTO-[1,3,4]THIADIAZOL-2-YLCARBAMOYL)-1-PHENYL-ETHYL]-CARBAMIC ACID BENZYL ESTER MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 31389:[DB06728 DB05931] DB06728|Aniline KLK1;ALB;CYP2E1 DB05931|Pegdinetanib KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 31390:[DB06728 DB01520] DB06728|Aniline KLK1;ALB;CYP2E1 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways GO:0042493| response to drug GRIN2A;CYP2E1 GO:0045471| response to ethanol GRIN3A;CYP2E1;GRIN2B;GRIN2A 31391:[DB06728 DB06927] DB06728|Aniline KLK1;ALB;CYP2E1 DB06927|[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE ESR2;NCOA1;ESR1 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA1;ALB 31392:[DB06728 DB00724] DB06728|Aniline KLK1;ALB;CYP2E1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 31393:[DB06728 DB06271] DB06728|Aniline KLK1;ALB;CYP2E1 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways GO:0043687| post-translational protein modification ALB;SERPINC1;SERPIND1 GO:0044267| cellular protein metabolic process SERPIND1;SERPINC1;ALB 31394:[DB06728 DB03467] DB06728|Aniline KLK1;ALB;CYP2E1 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP1B1 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;AKR1C1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2E1 GO:0055114| oxidation-reduction process AKR1C1;CYP2E1;CYP1B1;CYP19A1 GO:0042493| response to drug CYP2E1;ABCG2;ABCB1;ABCC1 GO:0006805| xenobiotic metabolic process CYP1B1;AKR1C1;CYP2E1 31395:[DB06728 DB02230] DB06728|Aniline KLK1;ALB;CYP2E1 DB02230|Immucillin-G PNP common genes common pathways GO:0042493| response to drug CYP2E1;PNP 31396:[DB06728 DB00367] DB06728|Aniline KLK1;ALB;CYP2E1 DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1;CYP3A4;SRD5A1 GO:0042493| response to drug SRD5A1;CYP2E1 GO:0009267| cellular response to starvation SRD5A1;ALB GO:0008202| steroid metabolic process SRD5A1;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31397:[DB06728 DB00364] DB06728|Aniline KLK1;ALB;CYP2E1 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation EGF;FGB;FGG;FGA;ALB GO:0043687| post-translational protein modification FGG;FGA;ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process FGG;FGA;ALB 31398:[DB06728 DB02911] DB06728|Aniline KLK1;ALB;CYP2E1 DB02911|2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS3 31399:[DB06728 DB07579] DB06728|Aniline KLK1;ALB;CYP2E1 DB07579|BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE APCS common genes common pathways GO:0044267| cellular protein metabolic process ALB;APCS 31400:[DB06728 DB07756] DB06728|Aniline KLK1;ALB;CYP2E1 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways 31401:[DB06728 DB08612] DB06728|Aniline KLK1;ALB;CYP2E1 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 31402:[DB06728 DB08347] DB06728|Aniline KLK1;ALB;CYP2E1 DB08347|4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile ADRB1 common genes common pathways 31403:[DB06728 DB13956] DB06728|Aniline KLK1;ALB;CYP2E1 DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1;UGT1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP1B1;CYP3A5;CYP2C19;CYP2C8;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;SLCO1A2;SLCO2B1;ALB;SLCO1C1;NCOA2 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLC22A8;SLCO1B3;SLCO1A2;SLC22A11;SLCO4A1;SLCO1C1;SLCO2B1;ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process UGT1A1;NR1I2;CYP1A1;CYP2C9;CYP1B1;CYP2C8;CYP2C19;CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0098869| ALB GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1;CYP1A1;CYP2C9;CYP2C19;CYP2C8 GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1;ABCG2;BECN1;UGT1A1;CYP1A1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1B1;CYP3A5;CYP2C8;CYP2C19;CYP1A1;CYP2C9;CYP3A7;CYP1A2;HSD17B2;CYP3A4;CYP2E1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9;CYP1A1;CYP2C8;CYP2C19;CYP1B1 GO:0043066| negative regulation of apoptotic process BECN1;ALB 31404:[DB06728 DB07142] DB06728|Aniline KLK1;ALB;CYP2E1 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 31405:[DB06728 DB08360] DB06728|Aniline KLK1;ALB;CYP2E1 DB08360|2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 31406:[DB06728 DB00875] DB06728|Aniline KLK1;ALB;CYP2E1 DB00875|Flupentixol DRD2;HTR2A;DRD1;ADRA1A;CHRM1;DDC;ABCB1 common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0042493| response to drug ADRA1A;DRD2;ABCB1;CYP2E1;HTR2A;DRD1 31407:[DB06728 DB02888] DB06728|Aniline KLK1;ALB;CYP2E1 DB02888|FKB-001 FKBP1A common genes common pathways 31408:[DB06728 DB03766] DB06728|Aniline KLK1;ALB;CYP2E1 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways GO:0055114| oxidation-reduction process GPHN;CYP2E1 31409:[DB06728 DB01193] DB06728|Aniline KLK1;ALB;CYP2E1 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0042493| response to drug ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 31410:[DB06728 DB01624] DB06728|Aniline KLK1;ALB;CYP2E1 DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug DRD2;ADRA1A;DRD1;HTR2A;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 31411:[DB06728 DB03552] DB06728|Aniline KLK1;ALB;CYP2E1 DB03552|3-Tyrosine TH common genes common pathways GO:0045471| response to ethanol CYP2E1;TH GO:0042493| response to drug TH;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;TH 31412:[DB06728 DB02464] DB06728|Aniline KLK1;ALB;CYP2E1 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS2;PRSS1 31413:[DB06728 DB03585] DB06728|Aniline KLK1;ALB;CYP2E1 DB03585|Oxyphenbutazone PLA2G2E;ALB;SLC22A6 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB 31414:[DB06728 DB03373] DB06728|Aniline KLK1;ALB;CYP2E1 DB03373|ZK-806711 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 31415:[DB06728 DB08208] DB06728|Aniline KLK1;ALB;CYP2E1 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways 31416:[DB06728 DB02468] DB06728|Aniline KLK1;ALB;CYP2E1 DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HMOX1 31417:[DB06728 DB08000] DB06728|Aniline KLK1;ALB;CYP2E1 DB08000|2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 31418:[DB06728 DB00171] DB06728|Aniline KLK1;ALB;CYP2E1 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0034375| high-density lipoprotein particle remodeling ABCG1;ALB GO:0006641| triglyceride metabolic process ACSL1;CYP2E1 GO:0006508| proteolysis AFG3L2;KLK1 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0008202| steroid metabolic process PRKAA1;CYP2E1;ABCA1 GO:0017144| drug metabolic process NT5C2;CYP2E1 GO:0042493| response to drug ABCC6;ABCC1;ABCC9;ABCB1;ADCY1;ACSL1;ABCC2;ABCA1;CYP2E1;ABCC8;ABCC4 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0043687| post-translational protein modification ALB;NAE1 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0043066| negative regulation of apoptotic process PRKAA1;ALB;ARAF;AKT1;ASNS GO:0002576| platelet degranulation ALB;ABCC4 31419:[DB06728 DB08184] DB06728|Aniline KLK1;ALB;CYP2E1 DB08184|2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 31420:[DB06728 DB05766] DB06728|Aniline KLK1;ALB;CYP2E1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0042493| response to drug CYP2E1;DRD2;DRD3 GO:0045471| response to ethanol CYP2E1;DRD2;DRD3 31421:[DB06728 DB00123] DB06728|Aniline KLK1;ALB;CYP2E1 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 31422:[DB06728 DB08883] DB06728|Aniline KLK1;ALB;CYP2E1 DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP3A5;CYP2B6 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP2B6;CYP2E1;CYP3A4;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2B6;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2B6;CYP3A5;CYP1A2;CYP2E1;CYP3A4 31423:[DB06728 DB01812] DB06728|Aniline KLK1;ALB;CYP2E1 DB01812|Adenosine-3'-5'-Diphosphate HS3ST1;SULT2B1;RNASE2;SULT1A1;HS3ST3A1;RNASE1;SULT2A1;SULT1E1;NDST1;acpS;SULT1B1;topA common genes common pathways GO:0008202| steroid metabolic process SULT1B1;SULT1A1;SULT1E1;SULT2A1;CYP2E1;SULT2B1 GO:0006805| xenobiotic metabolic process SULT1A1;SULT1B1;CYP2E1 31424:[DB06728 DB00352] DB06728|Aniline KLK1;ALB;CYP2E1 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC4 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0002576| platelet degranulation ALB;ABCC4 31425:[DB06728 DB03754] DB06728|Aniline KLK1;ALB;CYP2E1 DB03754|Tromethamine CANT1;NEIL1;AMD1;bioB;VEGFA;pgl;DCN common genes common pathways GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0002576| platelet degranulation VEGFA;ALB 31426:[DB06728 DB00445] DB06728|Aniline KLK1;ALB;CYP2E1 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2E1;UGT2B7 31427:[DB06728 DB07705] DB06728|Aniline KLK1;ALB;CYP2E1 DB07705|1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE CYP51A1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP51A1 GO:0055114| oxidation-reduction process CYP2E1;CYP51A1 31428:[DB06728 DB08519] DB06728|Aniline KLK1;ALB;CYP2E1 DB08519|N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 31429:[DB06728 DB04335] DB06728|Aniline KLK1;ALB;CYP2E1 DB04335|Inosine PNP;deoD;XDH;SLC28A3 common genes common pathways GO:0042493| response to drug PNP;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;XDH 31430:[DB06728 DB09066] DB06728|Aniline KLK1;ALB;CYP2E1 DB09066|Corifollitropin alfa FSHR common genes common pathways 31431:[DB06728 DB03909] DB06728|Aniline KLK1;ALB;CYP2E1 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways GO:0051659| maintenance of mitochondrion location ALB;ATP2A1 31432:[DB06728 DB07476] DB06728|Aniline KLK1;ALB;CYP2E1 DB07476|N-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE CA2 common genes common pathways 31433:[DB06728 DB02152] DB06728|Aniline KLK1;ALB;CYP2E1 DB02152|K-252a MET;MAP2K1 common genes common pathways 31434:[DB06728 DB03277] DB06728|Aniline KLK1;ALB;CYP2E1 DB03277|alpha-maltotriose AMY2B common genes common pathways 31435:[DB06728 DB06738] DB06728|Aniline KLK1;ALB;CYP2E1 DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2C9;CYP2B6;UGT1A9 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;GRIN2A GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP2E1;CYP3A4;PTGS1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2B6;CYP2C8;CYP2C19 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP2B6;CYP2C9;UGT1A9 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0045471| response to ethanol GRIN3A;OPRK1;OPRM1;GRIN1;CYP2E1;GRIN2B;GRIN2A 31436:[DB06728 DB04875] DB06728|Aniline KLK1;ALB;CYP2E1 DB04875|Pralnacasan CASP1 common genes common pathways GO:0006508| proteolysis KLK1;CASP1 31437:[DB06728 DB09215] DB06728|Aniline KLK1;ALB;CYP2E1 DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS1;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 31438:[DB06728 DB08205] DB06728|Aniline KLK1;ALB;CYP2E1 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 31439:[DB06728 DB05223] DB06728|Aniline KLK1;ALB;CYP2E1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0042493| response to drug HDAC1;HDAC2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;HDAC1;HDAC2;HDAC3 31440:[DB06728 DB03788] DB06728|Aniline KLK1;ALB;CYP2E1 DB03788|GC-24 THRB common genes common pathways 31441:[DB06728 DB11148] DB06728|Aniline KLK1;ALB;CYP2E1 DB11148|Butamben CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;BCHE;ORM1;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;KCNJ11;BCHE GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ORM1;ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31442:[DB06728 DB02678] DB06728|Aniline KLK1;ALB;CYP2E1 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways 31443:[DB06728 DB12698] DB06728|Aniline KLK1;ALB;CYP2E1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways 31444:[DB06728 DB01597] DB06728|Aniline KLK1;ALB;CYP2E1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;DPEP1 GO:0006508| proteolysis KLK1;DPEP1 GO:0043066| negative regulation of apoptotic process DPEP1;ALB GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLC22A6 31445:[DB06728 DB04048] DB06728|Aniline KLK1;ALB;CYP2E1 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PRDX2 GO:0055114| oxidation-reduction process CYP2E1;PRDX2 31446:[DB06728 DB00464] DB06728|Aniline KLK1;ALB;CYP2E1 DB00464|Sodium Tetradecyl Sulfate PROC;PROS1 common genes common pathways GO:0006508| proteolysis KLK1;PROC GO:0044267| cellular protein metabolic process ALB;PROC GO:0002576| platelet degranulation PROS1;ALB GO:0043066| negative regulation of apoptotic process ALB;PROC GO:0043687| post-translational protein modification PROC;ALB 31447:[DB06728 DB01709] DB06728|Aniline KLK1;ALB;CYP2E1 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways GO:0042493| response to drug CYP2E1;ENO3 31448:[DB06728 DB00031] DB06728|Aniline KLK1;ALB;CYP2E1 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0042493| response to drug CYP2E1;CALR GO:0043687| post-translational protein modification FGA;ALB GO:0002576| platelet degranulation FGA;ALB;CLEC3B;PLG;SERPINE1 GO:0043066| negative regulation of apoptotic process SERPINB2;ALB;PLAUR GO:0044267| cellular protein metabolic process FGA;ALB;PLG GO:0006508| proteolysis PLG;KLK1 GO:0006898| receptor-mediated endocytosis CALR;LRP1;ALB 31449:[DB06728 DB00095] DB06728|Aniline KLK1;ALB;CYP2E1 DB00095|Efalizumab ITGAL;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FCGR1A;FCGR2B GO:0006508| proteolysis C1R;C1QB;C1QC;C1QA;KLK1 31450:[DB06728 DB09526] DB06728|Aniline KLK1;ALB;CYP2E1 DB09526|Hydroquinone TYR;ALB common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process TYR;CYP2E1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31451:[DB06728 DB07456] DB06728|Aniline KLK1;ALB;CYP2E1 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways 31452:[DB06728 DB08467] DB06728|Aniline KLK1;ALB;CYP2E1 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways 31453:[DB06728 DB08304] DB06728|Aniline KLK1;ALB;CYP2E1 DB08304|(3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide GRIA2 common genes common pathways 31454:[DB06728 DB00642] DB06728|Aniline KLK1;ALB;CYP2E1 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways GO:0045471| response to ethanol CYP2E1;TYMS GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0055114| oxidation-reduction process DHFR;CYP2E1 GO:0042493| response to drug CYP2E1;TYMS 31455:[DB06728 DB09027] DB06728|Aniline KLK1;ALB;CYP2E1 DB09027|Ledipasvir ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 31456:[DB06728 DB04389] DB06728|Aniline KLK1;ALB;CYP2E1 DB04389|Ado-P-Ch2-P-Ps-Ado FHIT common genes common pathways 31457:[DB06728 DB02187] DB06728|Aniline KLK1;ALB;CYP2E1 DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;HSD17B1 31458:[DB06728 DB03013] DB06728|Aniline KLK1;ALB;CYP2E1 DB03013|Di(N-Acetyl-D-Glucosamine) LYZ;B4GALT1 common genes common pathways GO:0044267| cellular protein metabolic process LYZ;ALB GO:0001895| retina homeostasis ALB;LYZ 31459:[DB06728 DB08654] DB06728|Aniline KLK1;ALB;CYP2E1 DB08654|TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 31460:[DB06728 DB08416] DB06728|Aniline KLK1;ALB;CYP2E1 DB08416|(9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE CA2 common genes common pathways 31461:[DB06728 DB01207] DB06728|Aniline KLK1;ALB;CYP2E1 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0042493| response to drug CYP2E1;TBXA2R GO:0055114| oxidation-reduction process CYP2E1;TBXAS1 GO:0045471| response to ethanol CYP2E1;TBXA2R 31462:[DB06728 DB00043] DB06728|Aniline KLK1;ALB;CYP2E1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways 31463:[DB06728 DB02367] DB06728|Aniline KLK1;ALB;CYP2E1 DB02367|(1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 31464:[DB06728 DB01194] DB06728|Aniline KLK1;ALB;CYP2E1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CA3;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 31465:[DB06728 DB09343] DB06728|Aniline KLK1;ALB;CYP2E1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways 31466:[DB06728 DB08608] DB06728|Aniline KLK1;ALB;CYP2E1 DB08608|4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE PDK2 common genes common pathways 31467:[DB06728 DB00974] DB06728|Aniline KLK1;ALB;CYP2E1 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP19A1 GO:0042493| response to drug CYP2E1;ADA GO:0043066| negative regulation of apoptotic process ADA;ALB 31468:[DB06728 DB00240] DB06728|Aniline KLK1;ALB;CYP2E1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31469:[DB06728 DB05282] DB06728|Aniline KLK1;ALB;CYP2E1 DB05282|MCC AIFM1 common genes common pathways GO:0055114| oxidation-reduction process AIFM1;CYP2E1 31470:[DB06728 DB00954] DB06728|Aniline KLK1;ALB;CYP2E1 DB00954|Dirithromycin CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 31471:[DB06728 DB05249] DB06728|Aniline KLK1;ALB;CYP2E1 DB05249|FavId CSF3R common genes common pathways 31472:[DB06728 DB08448] DB06728|Aniline KLK1;ALB;CYP2E1 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 31473:[DB06728 DB12695] DB06728|Aniline KLK1;ALB;CYP2E1 DB12695|Phenethyl Isothiocyanate ACTA2;ACTB;ATP5B;ATP5L;CYB5B;DIABLO;FBXO41;HNRNPF;HNRNPK;HSPA4;HSPB1;HSPE1;HSPH1;MT-ND1;NUDC;PAPPA;PSMA3;PSMC3;RANBP1;S100A10;SF3A3;SMARCE1;SUCLG2;TPD52L2;TPM1;TPM3;TPM4;TUBA1A;TUBA3C;TUBA4A;TUBB1;TUBB2A;TUBB3;TUBB4B;TXN;UCHL1;USP14;VCP;VIM;YWHAB;YWHAE;YWHAH;YWHAQ;YWHAZ common genes common pathways GO:0043066| negative regulation of apoptotic process HSPB1;HNRNPK;YWHAZ;ALB GO:0002576| platelet degranulation ALB;TUBA4A GO:0043687| post-translational protein modification PSMC3;FBXO41;PSMA3;ALB GO:0055114| oxidation-reduction process CYP2E1;CYB5B;MT-ND1;TXN GO:0042493| response to drug MT-ND1;S100A10;CYP2E1 GO:0098869| TXN;ALB GO:0044267| cellular protein metabolic process ALB;PAPPA GO:0006805| xenobiotic metabolic process CYB5B;CYP2E1 GO:0006508| proteolysis PAPPA;UCHL1;USP14;PSMA3;KLK1 GO:0006898| receptor-mediated endocytosis ALB;HSPH1 GO:0001895| retina homeostasis ACTB;ALB;HSPB1 31474:[DB06728 DB03690] DB06728|Aniline KLK1;ALB;CYP2E1 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways 31475:[DB06728 DB04588] DB06728|Aniline KLK1;ALB;CYP2E1 DB04588|N-[4-(AMINOSULFONYL)BENZYL]-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 31476:[DB06728 DB02850] DB06728|Aniline KLK1;ALB;CYP2E1 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HPD 31477:[DB06728 DB03608] DB06728|Aniline KLK1;ALB;CYP2E1 DB03608|Diminazene PRDX5;PRSS1;AOC1 common genes common pathways GO:0055114| oxidation-reduction process AOC1;CYP2E1;PRDX5 GO:0042493| response to drug AOC1;CYP2E1 GO:0043066| negative regulation of apoptotic process PRDX5;ALB GO:0098869| PRDX5;ALB GO:0006508| proteolysis PRSS1;KLK1 GO:0006805| xenobiotic metabolic process AOC1;CYP2E1 31478:[DB06728 DB06600] DB06728|Aniline KLK1;ALB;CYP2E1 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 31479:[DB06728 DB06497] DB06728|Aniline KLK1;ALB;CYP2E1 DB06497|Aplaviroc CCR5 common genes common pathways 31480:[DB06728 DB08910] DB06728|Aniline KLK1;ALB;CYP2E1 DB08910|Pomalidomide CRBN;TNF;PTGS2;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP1A2;PTGS2;CYP2E1;ABCB1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2 31481:[DB06728 DB00860] DB06728|Aniline KLK1;ALB;CYP2E1 DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB 31482:[DB06728 DB08707] DB06728|Aniline KLK1;ALB;CYP2E1 DB08707|4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 31483:[DB06728 DB07717] DB06728|Aniline KLK1;ALB;CYP2E1 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways 31484:[DB06728 DB06176] DB06728|Aniline KLK1;ALB;CYP2E1 DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP3A5;CYP2B6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0042493| response to drug ABCB1;HDAC4;CYP1A1;HDAC1;ABCC1;HDAC2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2B6;CYP3A5;CYP2C19;CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process HDAC2;HDAC1;ALB GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A1;CYP2C19;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B3 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2B6;CYP1A1;CYP2C19 GO:0008202| steroid metabolic process CYP2B6;CYP1A1;CYP2C19;CYP3A5;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1B3;ALB 31485:[DB06728 DB00846] DB06728|Aniline KLK1;ALB;CYP2E1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 31486:[DB06728 DB06209] DB06728|Aniline KLK1;ALB;CYP2E1 DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9;CYP2B6 GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP2C19;CYP2B6;CYP2C9;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2B6;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9;CYP2B6 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;CES2;CYP2C19;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 31487:[DB06728 DB03243] DB06728|Aniline KLK1;ALB;CYP2E1 DB03243|4-Fluorobenzylamine PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 31488:[DB06728 DB04585] DB06728|Aniline KLK1;ALB;CYP2E1 DB04585|DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID ARG1 common genes common pathways GO:0042493| response to drug ARG1;CYP2E1 31489:[DB06728 DB01125] DB06728|Aniline KLK1;ALB;CYP2E1 DB01125|Anisindione GGCX common genes common pathways 31490:[DB06728 DB02205] DB06728|Aniline KLK1;ALB;CYP2E1 DB02205|6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One GAPDHS common genes common pathways GO:0055114| oxidation-reduction process GAPDHS;CYP2E1 31491:[DB06728 DB04175] DB06728|Aniline KLK1;ALB;CYP2E1 DB04175|Mdl-29951 FBP1 common genes common pathways 31492:[DB06728 DB00748] DB06728|Aniline KLK1;ALB;CYP2E1 DB00748|Carbinoxamine HRH1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C8 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2E1;CYP3A4 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 31493:[DB06728 DB01606] DB06728|Aniline KLK1;ALB;CYP2E1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A6;ALB 31494:[DB06728 DB00006] DB06728|Aniline KLK1;ALB;CYP2E1 DB00006|Bivalirudin F2;MPO common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process ALB;F2 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0055114| oxidation-reduction process MPO;CYP2E1 31495:[DB06728 DB00360] DB06728|Aniline KLK1;ALB;CYP2E1 DB00360|Sapropterin PAH;NOS3;TH;TPH1;PTGS2 common genes common pathways GO:0098869| PTGS2;ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PAH;NOS3;TPH1;CYP2E1;TH;PTGS2 GO:0042493| response to drug PTGS2;TH;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0045471| response to ethanol TH;CYP2E1 31496:[DB06728 DB03191] DB06728|Aniline KLK1;ALB;CYP2E1 DB03191|3-Oxiran-2ylalanine MAT1A common genes common pathways 31497:[DB06728 DB06909] DB06728|Aniline KLK1;ALB;CYP2E1 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways 31498:[DB06728 DB00851] DB06728|Aniline KLK1;ALB;CYP2E1 DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP1A1 GO:0017144| drug metabolic process CYP2E1;CYP1A2;CYP1A1 GO:0042493| response to drug CYP2E1;CYP1A2;CYP1A1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;PGD;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP1A1 GO:0018910| benzene metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 31499:[DB06728 DB00481] DB06728|Aniline KLK1;ALB;CYP2E1 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2B6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2B6;AOX1;CYP19A1;CYP2E1;CYP3A4 GO:0042493| response to drug UGT1A1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;SERPINB9 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2B6;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8;UGT1A1;AOX1;CYP2B6 31500:[DB06728 DB03598] DB06728|Aniline KLK1;ALB;CYP2E1 DB03598|Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide] CA2 common genes common pathways 31501:[DB06728 DB01009] DB06728|Aniline KLK1;ALB;CYP2E1 DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1;CYP2C9;CYP2C8 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0098869| PTGS2;PTGS1;ALB GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP2C8;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9;UGT1A1;CYP2C8 GO:0043252| sodium-independent organic anion transport SLC22A11;SLC22A7;SLCO1A2;SLC22A8;ALB;SLC22A6 GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0044267| cellular protein metabolic process ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 GO:0002576| platelet degranulation ABCC4;ALB GO:0010243| response to organic nitrogen ABCC4;PTGS2;CYP2E1 GO:0042493| response to drug UGT1A1;ABCC4;CYP2E1;PTGS2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP2E1;PTGS2;ABCC4;PTGS1 31502:[DB06728 DB01536] DB06728|Aniline KLK1;ALB;CYP2E1 DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process HSD17B1;AKR1C3;CYP3A4;CYP2E1;HSD3B1 GO:0009267| cellular response to starvation AKR1C3;ALB GO:0008202| steroid metabolic process AKR1C3;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 31503:[DB06728 DB12095] DB06728|Aniline KLK1;ALB;CYP2E1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0055114| oxidation-reduction process TPH1;TPH2;CYP2E1 31504:[DB06728 DB03233] DB06728|Aniline KLK1;ALB;CYP2E1 DB03233|Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways 31505:[DB06728 DB08806] DB06728|Aniline KLK1;ALB;CYP2E1 DB08806|Roxatidine acetate HRH2 common genes common pathways 31506:[DB06728 DB12498] DB06728|Aniline KLK1;ALB;CYP2E1 DB12498|Mogamulizumab CXCR4 common genes common pathways 31507:[DB06728 DB07388] DB06728|Aniline KLK1;ALB;CYP2E1 DB07388|ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2;NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2;NOS3 31508:[DB06728 DB00827] DB06728|Aniline KLK1;ALB;CYP2E1 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 31509:[DB06728 DB11967] DB06728|Aniline KLK1;ALB;CYP2E1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2C19 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process IL6;ALB GO:0042493| response to drug CYP1A2;CYP2E1;UGT1A1 GO:0043687| post-translational protein modification ALB;IL6 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2C19;UGT1A1 GO:0044267| cellular protein metabolic process IL6;ALB 31510:[DB06728 DB00629] DB06728|Aniline KLK1;ALB;CYP2E1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 31511:[DB06728 DB01632] DB06728|Aniline KLK1;ALB;CYP2E1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways 31512:[DB06728 DB04071] DB06728|Aniline KLK1;ALB;CYP2E1 DB04071|Cpad ADH1C common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1C 31513:[DB06728 DB00562] DB06728|Aniline KLK1;ALB;CYP2E1 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways GO:0042493| response to drug CYP2E1;CA9 31514:[DB06728 DB02821] DB06728|Aniline KLK1;ALB;CYP2E1 DB02821|Canaline OAT common genes common pathways 31515:[DB06728 DB05812] DB06728|Aniline KLK1;ALB;CYP2E1 DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes ALB common pathways GO:0055114| oxidation-reduction process CYP17A1;CYP2D6;CYP2C19;CYP2C8;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;CYP1A2;ABCC1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C19;CYP2C8;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ORM1;ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP17A1;CYP1A2;CYP3A4;CYP2E1;SULT2A1 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2C8;CYP2D6 GO:0098869| ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19;CYP2C8 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 31516:[DB06728 DB01370] DB06728|Aniline KLK1;ALB;CYP2E1 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes KLK1;ALB common pathways GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis TF;ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006508| proteolysis KLK1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process APP;ALB;TF GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation TF;APP;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug ATP1A1;CYP2E1 GO:0043687| post-translational protein modification ALB;APP;TF 31517:[DB06728 DB04818] DB06728|Aniline KLK1;ALB;CYP2E1 DB04818|Iproniazid MAOB;CYP2D6;CYP2C9 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process MAOB;CYP2C9;CYP2D6;CYP2E1 GO:0042493| response to drug MAOB;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9;CYP2D6 GO:0045471| response to ethanol MAOB;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9;CYP2D6 31518:[DB06728 DB00889] DB06728|Aniline KLK1;ALB;CYP2E1 DB00889|Granisetron HTR3A;CYP3A4;CYP1A1 common genes common pathways GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;HTR3A 31519:[DB06728 DB07019] DB06728|Aniline KLK1;ALB;CYP2E1 DB07019|N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE BACE1 common genes common pathways GO:0006508| proteolysis BACE1;KLK1 GO:0044267| cellular protein metabolic process ALB;BACE1 31520:[DB06728 DB02207] DB06728|Aniline KLK1;ALB;CYP2E1 DB02207|7-Nitroindazole NOS3;NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS3;NOS2;CYP2E1 31521:[DB06728 DB01114] DB06728|Aniline KLK1;ALB;CYP2E1 DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5;CYP2D6 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP2E1;CYP2D6;CYP3A5 GO:0042493| response to drug SLC6A4;CYP2E1;SLC6A3;SLC6A2 GO:0008202| steroid metabolic process CYP3A5;CYP2D6;CYP3A7;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 31522:[DB06728 DB03731] DB06728|Aniline KLK1;ALB;CYP2E1 DB03731|S-2-(Boronoethyl)-L-Cysteine ARG1;ARG2 common genes common pathways GO:0042493| response to drug ARG1;CYP2E1 31523:[DB06728 DB08905] DB06728|Aniline KLK1;ALB;CYP2E1 DB08905|Formestane CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31524:[DB06728 DB11294] DB06728|Aniline KLK1;ALB;CYP2E1 DB11294|Coccidioides immitis spherule HLA-A;HLA-A;HLA-B common genes common pathways 31525:[DB06728 DB08800] DB06728|Aniline KLK1;ALB;CYP2E1 DB08800|Chloropyramine HRH1 common genes common pathways 31526:[DB06728 DB07239] DB06728|Aniline KLK1;ALB;CYP2E1 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 31527:[DB06728 DB08384] DB06728|Aniline KLK1;ALB;CYP2E1 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways 31528:[DB06728 DB05398] DB06728|Aniline KLK1;ALB;CYP2E1 DB05398|C31G CD9 common genes common pathways GO:0002576| platelet degranulation CD9;ALB 31529:[DB06728 DB00054] DB06728|Aniline KLK1;ALB;CYP2E1 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:0006508| proteolysis C1QC;C1S;KLK1;C1QA;C1QB;C1R GO:0006898| receptor-mediated endocytosis VTN;FCGR2B;FCGR1A;ALB GO:0002576| platelet degranulation ITGA2B;ITGB3;ALB 31530:[DB06728 DB01277] DB06728|Aniline KLK1;ALB;CYP2E1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;IGF2R GO:0043066| negative regulation of apoptotic process IGF1R;ALB GO:0043687| post-translational protein modification IGFBP3;ALB GO:0044267| cellular protein metabolic process ALB;IGFBP3 31531:[DB06728 DB00461] DB06728|Aniline KLK1;ALB;CYP2E1 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0098869| PTGS1;PTGS2;ALB GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process PTGS2;MPO;ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS1;MPO;CYP1A2;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 31532:[DB06728 DB02746] DB06728|Aniline KLK1;ALB;CYP2E1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0042493| response to drug CYP2E1;PPARG GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0015721| bile acid and bile salt transport RXRA;SLCO2B1;ALB GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB 31533:[DB06728 DB02175] DB06728|Aniline KLK1;ALB;CYP2E1 DB02175|Malonic acid panD;SRC;SNRPA common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;SRC 31534:[DB06728 DB02118] DB06728|Aniline KLK1;ALB;CYP2E1 DB02118|CP-271485 MMP12 common genes common pathways GO:0006508| proteolysis MMP12;KLK1 31535:[DB06728 DB00892] DB06728|Aniline KLK1;ALB;CYP2E1 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 31536:[DB06728 DB02558] DB06728|Aniline KLK1;ALB;CYP2E1 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways GO:0006508| proteolysis MME;KLK1 31537:[DB06728 DB04591] DB06728|Aniline KLK1;ALB;CYP2E1 DB04591|N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 31538:[DB06728 DB08530] DB06728|Aniline KLK1;ALB;CYP2E1 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 31539:[DB06728 DB13925] DB06728|Aniline KLK1;ALB;CYP2E1 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways 31540:[DB06728 DB14060] DB06728|Aniline KLK1;ALB;CYP2E1 DB14060|NS-398 PTGS2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0098869| ALB;PTGS2 31541:[DB06728 DB07468] DB06728|Aniline KLK1;ALB;CYP2E1 DB07468|(3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 31542:[DB06728 DB01180] DB06728|Aniline KLK1;ALB;CYP2E1 DB01180|Rescinnamine ACE common genes common pathways GO:0006508| proteolysis ACE;KLK1 31543:[DB06728 DB00310] DB06728|Aniline KLK1;ALB;CYP2E1 DB00310|Chlorthalidone SLC12A1 common genes common pathways 31544:[DB06728 DB00216] DB06728|Aniline KLK1;ALB;CYP2E1 DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0045471| response to ethanol HTR1B;CYP2E1 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2C9;CYP2A6;CYP2E1;CYP3A4 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP2A6 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C9;CYP2E1;CYP2A6 GO:0042493| response to drug HTR2B;HTR1B;ABCB1;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;CYP3A4;CYP2A6;CYP2C19;CYP2D6;CYP2C9 31545:[DB06728 DB02170] DB06728|Aniline KLK1;ALB;CYP2E1 DB02170|1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One CSNK2A1 common genes common pathways 31546:[DB06728 DB00913] DB06728|Aniline KLK1;ALB;CYP2E1 DB00913|Anileridine OPRM1 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1 31547:[DB06728 DB08848] DB06728|Aniline KLK1;ALB;CYP2E1 DB08848|Guvacine SLC6A13;SLC6A1;SLC6A11;SLC6A12 common genes common pathways GO:0010243| response to organic nitrogen SLC6A1;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A11 31548:[DB06728 DB04854] DB06728|Aniline KLK1;ALB;CYP2E1 DB04854|Febuxostat XDH common genes common pathways GO:0055114| oxidation-reduction process XDH;CYP2E1 31549:[DB06728 DB00975] DB06728|Aniline KLK1;ALB;CYP2E1 DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ABCB11;ALB;SLCO2B1 GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1B1;SLCO1B3 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0042493| response to drug ABCB1;CYP2E1;ABCC4;ADA GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0002576| platelet degranulation ORM1;ALB;ABCC4 GO:0043066| negative regulation of apoptotic process ALB;ADA 31550:[DB06728 DB00528] DB06728|Aniline KLK1;ALB;CYP2E1 DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 31551:[DB06728 DB12537] DB06728|Aniline KLK1;ALB;CYP2E1 DB12537|Benzodiazepine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31552:[DB06728 DB02512] DB06728|Aniline KLK1;ALB;CYP2E1 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways GO:0002576| platelet degranulation ALB;ALDOA 31553:[DB06728 DB12589] DB06728|Aniline KLK1;ALB;CYP2E1 DB12589|Dacetuzumab CD40 common genes common pathways 31554:[DB06728 DB01012] DB06728|Aniline KLK1;ALB;CYP2E1 DB01012|Cinacalcet CASR;CYP3A4;CYP2D6;CYP1A2 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 31555:[DB06728 DB07106] DB06728|Aniline KLK1;ALB;CYP2E1 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways 31556:[DB06728 DB04961] DB06728|Aniline KLK1;ALB;CYP2E1 DB04961|Troxacitabine DCK common genes common pathways 31557:[DB06728 DB09097] DB06728|Aniline KLK1;ALB;CYP2E1 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways GO:0042493| response to drug DRD2;CYP2E1;DRD1 GO:0045471| response to ethanol CYP2E1;DRD2 31558:[DB06728 DB08629] DB06728|Aniline KLK1;ALB;CYP2E1 DB08629|N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE ATP5B common genes common pathways 31559:[DB06728 DB04886] DB06728|Aniline KLK1;ALB;CYP2E1 DB04886|Calanolide A CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31560:[DB06728 DB06936] DB06728|Aniline KLK1;ALB;CYP2E1 DB06936|N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis KLK1;F2 31561:[DB06728 DB01132] DB06728|Aniline KLK1;ALB;CYP2E1 DB01132|Pioglitazone PPARG;PPARD;PPARA;MAOB;CYP2C8;CYP3A4;PTGS1;CYP2C9;SLCO1B3;SLCO1B1 common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;PTGS1;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process PTGS1;CYP3A4;CYP2E1;CYP2C8;MAOB;CYP2C9 GO:0042493| response to drug PPARG;MAOB;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0098869| ALB;PTGS1 31562:[DB06728 DB07615] DB06728|Aniline KLK1;ALB;CYP2E1 DB07615|Tranilast HPGDS;CYP3A4;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9 31563:[DB06728 DB05075] DB06728|Aniline KLK1;ALB;CYP2E1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR;FLT4 31564:[DB06728 DB04736] DB06728|Aniline KLK1;ALB;CYP2E1 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways 31565:[DB06728 DB05364] DB06728|Aniline KLK1;ALB;CYP2E1 DB05364|ROX-888 CCL3 common genes common pathways 31566:[DB06728 DB05095] DB06728|Aniline KLK1;ALB;CYP2E1 DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0098869| PTGS2;ALB GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 31567:[DB06728 DB00278] DB06728|Aniline KLK1;ALB;CYP2E1 DB00278|Argatroban F2;CYP3A4;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5 GO:0044267| cellular protein metabolic process F2;ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0006508| proteolysis F2;KLK1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2E1;CYP3A4 31568:[DB06728 DB00067] DB06728|Aniline KLK1;ALB;CYP2E1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC2 31569:[DB06728 DB03216] DB06728|Aniline KLK1;ALB;CYP2E1 DB03216|(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine AHCY common genes common pathways 31570:[DB06728 DB00983] DB06728|Aniline KLK1;ALB;CYP2E1 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP2C9;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP2A6 GO:0055114| oxidation-reduction process CYP2A6;CYP2E1;CYP2C19;CYP2D6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP2C19;CYP2C9 GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C9;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;CYP2D6 31571:[DB06728 DB05204] DB06728|Aniline KLK1;ALB;CYP2E1 DB05204|XL418 BTK common genes common pathways 31572:[DB06728 DB02902] DB06728|Aniline KLK1;ALB;CYP2E1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;SULT1E1 31573:[DB06728 DB07116] DB06728|Aniline KLK1;ALB;CYP2E1 DB07116|1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;ALB 31574:[DB06728 DB00789] DB06728|Aniline KLK1;ALB;CYP2E1 DB00789|Gadopentetic acid PGD common genes common pathways GO:0055114| oxidation-reduction process PGD;CYP2E1 31575:[DB06728 DB07646] DB06728|Aniline KLK1;ALB;CYP2E1 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0042493| response to drug DHODH;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;DHODH 31576:[DB06728 DB04599] DB06728|Aniline KLK1;ALB;CYP2E1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0042493| response to drug DRD2;HTR2A;CYP2E1 GO:0045471| response to ethanol DRD2;CYP2E1 31577:[DB06728 DB01667] DB06728|Aniline KLK1;ALB;CYP2E1 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0042493| response to drug PNP;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 31578:[DB06728 DB00282] DB06728|Aniline KLK1;ALB;CYP2E1 DB00282|Pamidronate FDPS common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 31579:[DB06728 DB06831] DB06728|Aniline KLK1;ALB;CYP2E1 DB06831|2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE PIK3CG;PIK3CD common genes common pathways 31580:[DB06728 DB00935] DB06728|Aniline KLK1;ALB;CYP2E1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 31581:[DB06728 DB05016] DB06728|Aniline KLK1;ALB;CYP2E1 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B3;ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;SLC22A8;ALB;SLC22A6 31582:[DB06728 DB01341] DB06728|Aniline KLK1;ALB;CYP2E1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways 31583:[DB06728 DB02183] DB06728|Aniline KLK1;ALB;CYP2E1 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways 31584:[DB06728 DB00129] DB06728|Aniline KLK1;ALB;CYP2E1 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways GO:0042493| response to drug CYP2E1;OTC;ARG1 31585:[DB06728 DB05467] DB06728|Aniline KLK1;ALB;CYP2E1 DB05467|R667 RARG common genes common pathways GO:0043066| negative regulation of apoptotic process RARG;ALB 31586:[DB06728 DB08868] DB06728|Aniline KLK1;ALB;CYP2E1 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes CYP2E1 common pathways GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1 GO:0017144| drug metabolic process CYP4F12;CYP2E1;CYP4F2 GO:0008202| steroid metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;HDAC1;SPHK1 GO:0019373| epoxygenase P450 pathway CYP4F2;CYP2E1;CYP4F12 GO:0010243| response to organic nitrogen CYP2E1 GO:0055114| oxidation-reduction process CYP4F12;CYP2E1;CYP4F2 GO:0042493| response to drug HDAC1;CYP2E1 31587:[DB06728 DB00519] DB06728|Aniline KLK1;ALB;CYP2E1 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis KLK1;ACE GO:0006805| xenobiotic metabolic process CYP2E1;CES1 31588:[DB06728 DB09274] DB06728|Aniline KLK1;ALB;CYP2E1 DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP2A6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2A6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31589:[DB06728 DB03397] DB06728|Aniline KLK1;ALB;CYP2E1 DB03397|Uridine-Diphosphate-N-Acetylglucosamine glmU;UAP1;murA;GALE;glmU;EXTL2;MGAT1 common genes common pathways 31590:[DB06728 DB01908] DB06728|Aniline KLK1;ALB;CYP2E1 DB01908|RU85493 SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 31591:[DB06728 DB04140] DB06728|Aniline KLK1;ALB;CYP2E1 DB04140|1-Benzyl-3-(4-Methoxy-Benzenesulfonyl)-6-Oxo-Hexahydro-Pyrimidine-4-Carboxylic Acid Hydroxyamide MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 31592:[DB06728 DB00575] DB06728|Aniline KLK1;ALB;CYP2E1 DB00575|Clonidine ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP3A5;SLC22A3;SLC22A5;SLC22A4;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A1;CYP1A2;CYP2E1 GO:0042493| response to drug ADRA1A;ABCB1;CYP1A1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP1A1;CYP1A2;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP1A1 GO:0008202| steroid metabolic process CYP3A5;CYP2D6;CYP1A1;CYP3A4;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6;CYP1A1 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 31593:[DB06728 DB11919] DB06728|Aniline KLK1;ALB;CYP2E1 DB11919|6-O-benzylguanine CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31594:[DB06728 DB06962] DB06728|Aniline KLK1;ALB;CYP2E1 DB06962|(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone TPSB2 common genes common pathways GO:0006508| proteolysis TPSB2;KLK1 31595:[DB06728 DB06928] DB06728|Aniline KLK1;ALB;CYP2E1 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways GO:0006508| proteolysis FOLH1;KLK1 31596:[DB06728 DB08907] DB06728|Aniline KLK1;ALB;CYP2E1 DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process UGT2B4;UGT1A9;CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;UGT1A9 GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug ABCC2;ABCB1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;ORM1 31597:[DB06728 DB06376] DB06728|Aniline KLK1;ALB;CYP2E1 DB06376|CHGN111 CLK1 common genes common pathways 31598:[DB06728 DB11273] DB06728|Aniline KLK1;ALB;CYP2E1 DB11273|Dihydroergocornine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4 common genes common pathways GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;HTR3A;HTR1B GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0042493| response to drug HTR1B;ADRA1A;HTR2C;HTR2B;HTR2A;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31599:[DB06728 DB12248] DB06728|Aniline KLK1;ALB;CYP2E1 DB12248|Tulobuterol ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 31600:[DB06728 DB01438] DB06728|Aniline KLK1;ALB;CYP2E1 DB01438|Phenazopyridine SCN1A common genes common pathways 31601:[DB06728 DB02518] DB06728|Aniline KLK1;ALB;CYP2E1 DB02518|N-Acetylalanine AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 31602:[DB06728 DB11575] DB06728|Aniline KLK1;ALB;CYP2E1 DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes ALB common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;ALB GO:0044267| cellular protein metabolic process ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB;ORM1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 31603:[DB06728 DB08881] DB06728|Aniline KLK1;ALB;CYP2E1 DB08881|Vemurafenib BRAF;CYP1A2;CYP2D6;CYP3A4;CYP2C9;CYP2C8;CYP2B6;ALB;ORM1;ABCC1;ABCG2 common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C8;CYP2C9;CYP2B6 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB;ORM1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2B6;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;BRAF GO:0042493| response to drug CYP1A2;CYP2E1;ABCG2;ABCC1 GO:0055114| oxidation-reduction process CYP2C8;CYP2D6;CYP2B6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;CYP2D6 GO:0098869| ALB GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 31604:[DB06728 DB01084] DB06728|Aniline KLK1;ALB;CYP2E1 DB01084|Emedastine HRH1 common genes common pathways 31605:[DB06728 DB02759] DB06728|Aniline KLK1;ALB;CYP2E1 DB02759|4-Methylumbelliferyl Chitobiose LYZ common genes common pathways GO:0001895| retina homeostasis LYZ;ALB GO:0044267| cellular protein metabolic process LYZ;ALB 31606:[DB06728 DB11327] DB06728|Aniline KLK1;ALB;CYP2E1 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process NOS2;PTGS2;CYP2E1 31607:[DB06728 DB14542] DB06728|Aniline KLK1;ALB;CYP2E1 DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0042493| response to drug CYP2E1;HSD11B2;ANXA1;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP11B1;CYP11B2;CYP3A7;CYP2C8;CYP3A5;HSD11B2;HSD3B1 GO:0043066| negative regulation of apoptotic process ALB;ANXA1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP2E1;CYP3A4;CYP11B2;CYP11B1;CYP3A7 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 31608:[DB06728 DB06083] DB06728|Aniline KLK1;ALB;CYP2E1 DB06083|Tapinarof IL12B;IL2;IL6;CXCL8 common genes common pathways GO:0045471| response to ethanol CYP2E1;IL2 GO:0044267| cellular protein metabolic process ALB;IL6 GO:0043066| negative regulation of apoptotic process ALB;IL2;IL6 GO:0043687| post-translational protein modification ALB;IL6 31609:[DB06728 DB00626] DB06728|Aniline KLK1;ALB;CYP2E1 DB00626|Bacitracin IDE;A2M common genes common pathways GO:0002576| platelet degranulation ALB;A2M GO:0006508| proteolysis KLK1;IDE 31610:[DB06728 DB07288] DB06728|Aniline KLK1;ALB;CYP2E1 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways 31611:[DB06728 DB00541] DB06728|Aniline KLK1;ALB;CYP2E1 DB00541|Vincristine TUBB;TUBA4A;CYP3A5;CYP3A7;CYP3A4;ABCB1;ABCC3;SLC22A3;ABCC1;ABCC10;ABCC2;ABCB11;ABCG2;RALBP1;SLCO1B1;SLCO1B3 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0002576| platelet degranulation TUBA4A;ALB GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0042493| response to drug ABCC1;ABCB1;ABCC2;ABCG2;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ABCC3;ALB;SLCO1B3;ABCB11;SLCO1B1 31612:[DB06728 DB11574] DB06728|Aniline KLK1;ALB;CYP2E1 DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A43;CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0042493| response to drug CYP2E1;ABCB1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5 31613:[DB06728 DB02445] DB06728|Aniline KLK1;ALB;CYP2E1 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 31614:[DB06728 DB00583] DB06728|Aniline KLK1;ALB;CYP2E1 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 GO:0006641| triglyceride metabolic process CPT1A;CYP2E1;SLC22A4 GO:0055114| oxidation-reduction process CYP2E1;XDH;MPO GO:0042493| response to drug CPT1A;CYP2E1 GO:0043066| negative regulation of apoptotic process MPO;ALB GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1B1;ALB 31615:[DB06728 DB05212] DB06728|Aniline KLK1;ALB;CYP2E1 DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process NFKB1;ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 31616:[DB06728 DB05944] DB06728|Aniline KLK1;ALB;CYP2E1 DB05944|Varlitinib ERBB2;EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 31617:[DB06728 DB05009] DB06728|Aniline KLK1;ALB;CYP2E1 DB05009|Apadenoson ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;CYP2E1 GO:0044267| cellular protein metabolic process ALB;ADORA2A 31618:[DB06728 DB07156] DB06728|Aniline KLK1;ALB;CYP2E1 DB07156|(4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IGF1R 31619:[DB06728 DB11828] DB06728|Aniline KLK1;ALB;CYP2E1 DB11828|Neratinib EGFR;CYP3A4;FMO3;ALB;ORM1;ORM2;ABCB1 common genes ALB common pathways GO:0006805| xenobiotic metabolic process FMO3;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0055114| oxidation-reduction process FMO3;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0002576| platelet degranulation ORM2;ORM1;ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 31620:[DB06728 DB12518] DB06728|Aniline KLK1;ALB;CYP2E1 DB12518|Raclopride DRD2 common genes common pathways GO:0045471| response to ethanol DRD2;CYP2E1 GO:0042493| response to drug DRD2;CYP2E1 31621:[DB06728 DB05281] DB06728|Aniline KLK1;ALB;CYP2E1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0042493| response to drug CYP2E1;BCL2 GO:0043066| negative regulation of apoptotic process ALB;BCL2 GO:0002576| platelet degranulation ALB;TUBA4A 31622:[DB06728 DB11311] DB06728|Aniline KLK1;ALB;CYP2E1 DB11311|Prothrombin FGA;FGB;F13A1;CPB2;F10 common genes common pathways GO:0006508| proteolysis F10;CPB2;KLK1 GO:0044267| cellular protein metabolic process ALB;FGA GO:0002576| platelet degranulation ALB;F13A1;FGA;FGB GO:0043687| post-translational protein modification ALB;FGA GO:0042493| response to drug CPB2;CYP2E1 31623:[DB06728 DB08277] DB06728|Aniline KLK1;ALB;CYP2E1 DB08277|2-(2-CHLORO-4-FLUOROPHENOXY)-2-METHYL-N-[(1R,2S,3S,5S,7S)-5-(METHYLSULFONYL)-2-ADAMANTYL]PROPANAMIDE HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1 GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 31624:[DB06728 DB08391] DB06728|Aniline KLK1;ALB;CYP2E1 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 31625:[DB06728 DB07775] DB06728|Aniline KLK1;ALB;CYP2E1 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 31626:[DB06728 DB07866] DB06728|Aniline KLK1;ALB;CYP2E1 DB07866|(5S)-2-(cyclooctylamino)-5-methyl-5-propyl-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;HSD11B1 GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 31627:[DB06728 DB06439] DB06728|Aniline KLK1;ALB;CYP2E1 DB06439|Tyloxapol LPL common genes common pathways GO:0006641| triglyceride metabolic process LPL;CYP2E1 GO:0042493| response to drug LPL;CYP2E1 31628:[DB06728 DB00158] DB06728|Aniline KLK1;ALB;CYP2E1 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes CYP2E1;ALB common pathways GO:0006898| receptor-mediated endocytosis ALB;FOLR1;FOLR2 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol GGH;CYP2E1 GO:0006508| proteolysis KLK1;GGH GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1 GO:0015721| bile acid and bile salt transport ALB;ABCC3 GO:0010193| response to ozone CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0019373| epoxygenase P450 pathway CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0018910| benzene metabolic process CYP2E1 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0042493| response to drug ABCC4;GGH;MTHFR;CYP2E1;ABCG2 GO:0055114| oxidation-reduction process ABCC4;MTHFR;CYP2E1 GO:0043687| post-translational protein modification ALB 31629:[DB06728 DB12702] DB06728|Aniline KLK1;ALB;CYP2E1 DB12702|Velusetrag HTR4 common genes common pathways 31630:[DB06728 DB03554] DB06728|Aniline KLK1;ALB;CYP2E1 DB03554|5-Iodouracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP2E1 31631:[DB06728 DB08473] DB06728|Aniline KLK1;ALB;CYP2E1 DB08473|5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole CSNK2A1 common genes common pathways 31632:[DB06728 DB04356] DB06728|Aniline KLK1;ALB;CYP2E1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 31633:[DB06728 DB08056] DB06728|Aniline KLK1;ALB;CYP2E1 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0042493| response to drug CYP2E1;LCK 31634:[DB06728 DB07124] DB06728|Aniline KLK1;ALB;CYP2E1 DB07124|(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE PRKACA common genes common pathways 31635:[DB06728 DB02378] DB06728|Aniline KLK1;ALB;CYP2E1 DB02378|MMI-175 BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process ALB;BACE1 31636:[DB06728 DB00376] DB06728|Aniline KLK1;ALB;CYP2E1 DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways 31637:[DB06728 DB00901] DB06728|Aniline KLK1;ALB;CYP2E1 DB00901|Bitolterol ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 31638:[DB06728 DB00692] DB06728|Aniline KLK1;ALB;CYP2E1 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A 31639:[DB06728 DB07167] DB06728|Aniline KLK1;ALB;CYP2E1 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways GO:0043066| negative regulation of apoptotic process CSF1R;ALB 31640:[DB06728 DB01041] DB06728|Aniline KLK1;ALB;CYP2E1 DB01041|Thalidomide CRBN;TNF;NFKB1;FGFR2;PTGS2;ORM1;ORM2;CYP2C19;CYP1A1;CYP2E1;CYP2C9;PTGS1;PTGS2;CYP3A5 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0098869| PTGS2;PTGS1;ALB GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A5;CYP2C19;CYP2C9;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug CYP1A1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CYP2C19;CYP3A5;CYP2E1;PTGS2;PTGS1 GO:0043066| negative regulation of apoptotic process ALB;NFKB1;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9;CYP1A1 GO:0002576| platelet degranulation ORM1;ORM2;ALB GO:0018910| benzene metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1;CYP2C9;CYP3A5;CYP2C19 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;CYP1A1 GO:0045471| response to ethanol FGFR2;CYP2E1 31641:[DB06728 DB01303] DB06728|Aniline KLK1;ALB;CYP2E1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0043252| sodium-independent organic anion transport SLC22A7;ALB GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0043066| negative regulation of apoptotic process ALB;ADORA1;PDE3A;HDAC2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug ADORA2A;PDE3A;HDAC2;CYP2E1;CYP1A2 31642:[DB06728 DB08341] DB06728|Aniline KLK1;ALB;CYP2E1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0042493| response to drug CYP2E1;PTK2B GO:0010243| response to organic nitrogen CYP2E1;PTK2B GO:0043066| negative regulation of apoptotic process ALB;PTK2B GO:0045471| response to ethanol CYP2E1;PTK2B 31643:[DB06728 DB13627] DB06728|Aniline KLK1;ALB;CYP2E1 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 31644:[DB06728 DB07515] DB06728|Aniline KLK1;ALB;CYP2E1 DB07515|1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 31645:[DB06728 DB05036] DB06728|Aniline KLK1;ALB;CYP2E1 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways GO:0043066| negative regulation of apoptotic process TERT;ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGES3 31646:[DB06728 DB00234] DB06728|Aniline KLK1;ALB;CYP2E1 DB00234|Reboxetine SLC6A2;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0042493| response to drug CYP2E1;SLC6A2;ABCB1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 31647:[DB06728 DB07969] DB06728|Aniline KLK1;ALB;CYP2E1 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways 31648:[DB06728 DB03902] DB06728|Aniline KLK1;ALB;CYP2E1 DB03902|Oxalic Acid SRC;SLCO2B1;SLC22A8 common genes common pathways GO:0042493| response to drug SRC;CYP2E1 GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLCO2B1 31649:[DB06728 DB04249] DB06728|Aniline KLK1;ALB;CYP2E1 DB04249|Zinc Substituted Heme C CYCS common genes common pathways GO:0055114| oxidation-reduction process CYCS;CYP2E1 31650:[DB06728 DB01890] DB06728|Aniline KLK1;ALB;CYP2E1 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways GO:0002576| platelet degranulation ALB;IGF1 GO:0043066| negative regulation of apoptotic process IGF1;ALB GO:0044267| cellular protein metabolic process ALB;IGF1 31651:[DB06728 DB03220] DB06728|Aniline KLK1;ALB;CYP2E1 DB03220|FR233623 ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ADA;ALB GO:0042493| response to drug CYP2E1;ADA 31652:[DB06728 DB08237] DB06728|Aniline KLK1;ALB;CYP2E1 DB08237|2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) POLK common genes common pathways 31653:[DB06728 DB03899] DB06728|Aniline KLK1;ALB;CYP2E1 DB03899|9-Butyl-8-(4-Methoxybenzyl)-9h-Purin-6-Amine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 31654:[DB06728 DB14014] DB06728|Aniline KLK1;ALB;CYP2E1 DB14014|SR-9011 NR1D2;NR1D1 common genes common pathways 31655:[DB06728 DB00535] DB06728|Aniline KLK1;ALB;CYP2E1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A6;ALB GO:0055114| oxidation-reduction process CYP2E1;MPO GO:0043066| negative regulation of apoptotic process MPO;ALB 31656:[DB06728 DB05070] DB06728|Aniline KLK1;ALB;CYP2E1 DB05070|ADX10059 GRM5 common genes common pathways 31657:[DB06728 DB05481] DB06728|Aniline KLK1;ALB;CYP2E1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;SERPINA1 GO:0002576| platelet degranulation SERPINA1;ALB GO:0043687| post-translational protein modification SERPINA1;ALB 31658:[DB06728 DB07596] DB06728|Aniline KLK1;ALB;CYP2E1 DB07596|(17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate CA2 common genes common pathways 31659:[DB06728 DB13456] DB06728|Aniline KLK1;ALB;CYP2E1 DB13456|Midecamycin CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31660:[DB06728 DB08443] DB06728|Aniline KLK1;ALB;CYP2E1 DB08443|2-(1H-pyrrol-1-ylcarbonyl)benzene-1,3,5-triol HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 31661:[DB06728 DB14520] DB06728|Aniline KLK1;ALB;CYP2E1 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:0044267| cellular protein metabolic process TF;ALB GO:0002576| platelet degranulation TF;ALB;ITGB3 GO:0042493| response to drug CALR;CYP2E1 GO:0043687| post-translational protein modification ALB;TF GO:0006898| receptor-mediated endocytosis ALB;CALR;TFRC GO:0001895| retina homeostasis ALB;TF 31662:[DB06728 DB04991] DB06728|Aniline KLK1;ALB;CYP2E1 DB04991|XL784 ADAM10 common genes common pathways GO:0044267| cellular protein metabolic process ALB;ADAM10 GO:0043687| post-translational protein modification ALB;ADAM10 GO:0006508| proteolysis KLK1;ADAM10 31663:[DB06728 DB00723] DB06728|Aniline KLK1;ALB;CYP2E1 DB00723|Methoxamine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A 31664:[DB06728 DB11799] DB06728|Aniline KLK1;ALB;CYP2E1 DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2E1 31665:[DB06728 DB01424] DB06728|Aniline KLK1;ALB;CYP2E1 DB01424|Aminophenazone CYP2C19;CYP1A2;CYP2C8;CYP2C9;CYP2D6;CYP3A4;CYP2C18;CYP17A1;SLC22A6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2C18;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C18;CYP1A2;CYP2E1;CYP3A4;CYP17A1;CYP2C8;CYP2C19;CYP2D6;CYP2C9 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP17A1;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1;CYP1A2 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP1A2;CYP2C18 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19 31666:[DB06728 DB00025] DB06728|Aniline KLK1;ALB;CYP2E1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0044267| cellular protein metabolic process PROC;F2;ALB GO:0055114| oxidation-reduction process CYP2E1;PHYH GO:0043687| post-translational protein modification ALB;PROC GO:0042493| response to drug CYP2E1;CALR GO:0002576| platelet degranulation ALB;VWF GO:0043066| negative regulation of apoptotic process PROC;ALB;HSPA5 GO:0006898| receptor-mediated endocytosis CALR;LRP1;ALB;ASGR2 GO:0006508| proteolysis KLK1;PROC;F2;F9;F10 31667:[DB06728 DB07086] DB06728|Aniline KLK1;ALB;CYP2E1 DB07086|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL NCOA2;ESR1 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 31668:[DB06728 DB12329] DB06728|Aniline KLK1;ALB;CYP2E1 DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;MAOA GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 31669:[DB06728 DB01365] DB06728|Aniline KLK1;ALB;CYP2E1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB 31670:[DB06728 DB02644] DB06728|Aniline KLK1;ALB;CYP2E1 DB02644|N-Omega-Propyl-L-Arginine NOS2;NOS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2;NOS1 31671:[DB06728 DB01157] DB06728|Aniline KLK1;ALB;CYP2E1 DB01157|Trimetrexate DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP2E1 31672:[DB06728 DB07853] DB06728|Aniline KLK1;ALB;CYP2E1 DB07853|[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE SLK;CAMK2D;STK26 common genes common pathways GO:0009267| cellular response to starvation STK26;ALB 31673:[DB06728 DB05085] DB06728|Aniline KLK1;ALB;CYP2E1 DB05085|TM30339 NPY4R common genes common pathways 31674:[DB06728 DB09211] DB06728|Aniline KLK1;ALB;CYP2E1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways 31675:[DB06728 DB03120] DB06728|Aniline KLK1;ALB;CYP2E1 DB03120|Para-Toluene Sulfonate LYZ;CTSH common genes common pathways GO:0001895| retina homeostasis LYZ;ALB GO:0006508| proteolysis KLK1;CTSH GO:0044267| cellular protein metabolic process CTSH;ALB;LYZ GO:0043066| negative regulation of apoptotic process ALB;CTSH 31676:[DB06728 DB00219] DB06728|Aniline KLK1;ALB;CYP2E1 DB00219|Oxyphenonium CHRM1 common genes common pathways 31677:[DB06728 DB13928] DB06728|Aniline KLK1;ALB;CYP2E1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes ALB common pathways GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug LPL;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006641| triglyceride metabolic process CYP2E1;LPL GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006508| proteolysis KLK1;MME;DPP4 31678:[DB06728 DB06771] DB06728|Aniline KLK1;ALB;CYP2E1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 31679:[DB06728 DB06800] DB06728|Aniline KLK1;ALB;CYP2E1 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 31680:[DB06728 DB13139] DB06728|Aniline KLK1;ALB;CYP2E1 DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 31681:[DB06728 DB03347] DB06728|Aniline KLK1;ALB;CYP2E1 DB03347|Triethyl Phosphate TP53 common genes common pathways GO:0043066| negative regulation of apoptotic process TP53;ALB GO:0010243| response to organic nitrogen CYP2E1;TP53 GO:0042493| response to drug TP53;CYP2E1 GO:0045471| response to ethanol CYP2E1;TP53 31682:[DB06728 DB05146] DB06728|Aniline KLK1;ALB;CYP2E1 DB05146|XL820 KDR;KIT;PDGFRA;PDGFRB common genes common pathways GO:0043066| negative regulation of apoptotic process PDGFRB;ALB;KDR GO:0043069| negative regulation of programmed cell death ALB;KIT 31683:[DB06728 DB01152] DB06728|Aniline KLK1;ALB;CYP2E1 DB01152|Candicidin CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31684:[DB06728 DB00313] DB06728|Aniline KLK1;ALB;CYP2E1 DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes ALB common pathways GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process UGT1A3;CYP2A6;CYP2E1;CYP3A4;UGT1A10;CYP1A2;UGT1A6;CYP2C19;CYP2C8;CYP2B6;CYP2C9;UGT1A4;UGT1A1;UGT1A9;UGT1A8 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A7;SLC22A6;ALB;SLCO2B1 GO:0008202| steroid metabolic process UGT2B7;CYP2E1;CYP3A4;CYP2A6;CYP1A2;CYP3A5;CYP2C19;CYP2C8;CYP2C9;CYP2B6;UGT1A1;UGT1A8;UGT2B15 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB GO:0044267| cellular protein metabolic process ALB GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP1A2;CYP2C18;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;PPARD;HDAC2 GO:0002576| platelet degranulation ALB GO:0042493| response to drug ABAT;PPARG;UGT1A1;HDAC2;CYP2E1;SCN11A;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP2C8;ALDH5A1;CYP2C9;CYP2B6;ACADSB;CYP2C18;OGDH;PTGS1;CYP2E1;CYP3A4;CYP2A6;CYP1A2 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;UGT1A9;UGT2B15;CYP3A5;CYP2C8;CYP2C19;CYP3A4;CYP2E1;UGT1A6;CYP1A2;CYP2C18;PTGS1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;UGT1A1 GO:0045471| response to ethanol ABAT;UGT1A1;CYP2E1 31685:[DB06728 DB00354] DB06728|Aniline KLK1;ALB;CYP2E1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways 31686:[DB06728 DB04218] DB06728|Aniline KLK1;ALB;CYP2E1 DB04218|1-Deaza-Adenosine ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0042493| response to drug ADA;CYP2E1 31687:[DB06728 DB00476] DB06728|Aniline KLK1;ALB;CYP2E1 DB00476|Duloxetine SLC6A4;SLC6A2;SLC6A3;CYP1A2;CYP2D6;CYP3A4 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0042493| response to drug SLC6A2;SLC6A3;CYP1A2;CYP2E1;SLC6A4 GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 31688:[DB06728 DB04831] DB06728|Aniline KLK1;ALB;CYP2E1 DB04831|Tienilic acid CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 31689:[DB06728 DB05399] DB06728|Aniline KLK1;ALB;CYP2E1 DB05399|Succinobucol VCAM1 common genes common pathways GO:0045471| response to ethanol CYP2E1;VCAM1 GO:0055114| oxidation-reduction process CYP2E1;VCAM1 31690:[DB06728 DB11963] DB06728|Aniline KLK1;ALB;CYP2E1 DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0042493| response to drug UGT1A1;ABCB1;ABCG2;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2D6 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2C9;UGT1A1;CYP2D6;CYP2E1;CYP3A4 GO:0098869| ALB GO:0017144| drug metabolic process CYP2C9;UGT1A1;CYP2D6;CYP3A4;CYP2E1 31691:[DB06728 DB07321] DB06728|Aniline KLK1;ALB;CYP2E1 DB07321|2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE FBP1 common genes common pathways 31692:[DB06728 DB02698] DB06728|Aniline KLK1;ALB;CYP2E1 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0044267| cellular protein metabolic process TTR;ALB 31693:[DB06728 DB08342] DB06728|Aniline KLK1;ALB;CYP2E1 DB08342|S-PALMITOYL-L-CYSTEINE TRAPPC6A;TRAPPC3;TRAPPC6B;TRAPPC5;TRAPPC4;TRAPPC1 common genes common pathways 31694:[DB06728 DB02918] DB06728|Aniline KLK1;ALB;CYP2E1 DB02918|Zardaverine PDE4D common genes common pathways 31695:[DB06728 DB14512] DB06728|Aniline KLK1;ALB;CYP2E1 DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 31696:[DB06728 DB01752] DB06728|Aniline KLK1;ALB;CYP2E1 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways GO:0045471| response to ethanol CYP2E1;SETD7 31697:[DB06728 DB08610] DB06728|Aniline KLK1;ALB;CYP2E1 DB08610|N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE PDK2 common genes common pathways 31698:[DB06728 DB04379] DB06728|Aniline KLK1;ALB;CYP2E1 DB04379|N-Methyl-N-(Methylbenzyl)Formamide REN;CYP2E1 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2E1 GO:0017144| drug metabolic process CYP2E1 GO:0055114| oxidation-reduction process CYP2E1 GO:0042493| response to drug CYP2E1;REN GO:0010243| response to organic nitrogen CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006508| proteolysis KLK1;REN GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 31699:[DB06728 DB01970] DB06728|Aniline KLK1;ALB;CYP2E1 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways 31700:[DB06728 DB07162] DB06728|Aniline KLK1;ALB;CYP2E1 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways 31701:[DB06728 DB00185] DB06728|Aniline KLK1;ALB;CYP2E1 DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways GO:0017144| drug metabolic process FMO1;CYP2E1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1;FMO1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;FMO1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 31702:[DB06728 DB01419] DB06728|Aniline KLK1;ALB;CYP2E1 DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0098869| PTGS1;PTGS2;ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 31703:[DB06728 DB09123] DB06728|Aniline KLK1;ALB;CYP2E1 DB09123|Dienogest PGR;AR;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 31704:[DB06728 DB07190] DB06728|Aniline KLK1;ALB;CYP2E1 DB07190|3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 31705:[DB06728 DB00887] DB06728|Aniline KLK1;ALB;CYP2E1 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug SLC12A5;PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0015721| bile acid and bile salt transport ALB;SLC10A1;SLCO1A2 GO:0098869| PTGS2;ALB GO:0043252| sodium-independent organic anion transport SLC22A7;SLC22A11;SLC22A8;SLCO1A2;ALB;SLC22A6 31706:[DB06728 DB00756] DB06728|Aniline KLK1;ALB;CYP2E1 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;SDHD;GLUD1 31707:[DB06728 DB04450] DB06728|Aniline KLK1;ALB;CYP2E1 DB04450|Heptyl 1-Thiohexopyranoside RHO;fpr;acpP common genes common pathways 31708:[DB06728 DB04000] DB06728|Aniline KLK1;ALB;CYP2E1 DB04000|Bromo-Willardiine GRIA2 common genes common pathways 31709:[DB06728 DB03622] DB06728|Aniline KLK1;ALB;CYP2E1 DB03622|2-Hydroxy-5-[4-(2-Hydroxy-Ethyl)-Piperidin-1-Yl]-5-Phenyl-1h-Pyrimidine-4,6-Dione MMP8 common genes common pathways GO:0006508| proteolysis KLK1;MMP8 31710:[DB06728 DB09228] DB06728|Aniline KLK1;ALB;CYP2E1 DB09228|Conestat alfa C1R;C1S;KLKB1;F12;F2;F11;PLAT common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis C1R;F2;PLAT;F12;KLKB1;C1S;KLK1;F11 31711:[DB06728 DB07626] DB06728|Aniline KLK1;ALB;CYP2E1 DB07626|4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 31712:[DB06728 DB01689] DB06728|Aniline KLK1;ALB;CYP2E1 DB01689|Inhibitor Idd 384 AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 31713:[DB06728 DB09325] DB06728|Aniline KLK1;ALB;CYP2E1 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways GO:0055114| oxidation-reduction process MT-CO1;CYP2E1 31714:[DB06728 DB00115] DB06728|Aniline KLK1;ALB;CYP2E1 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0006898| receptor-mediated endocytosis AMN;CUBN;ALB GO:0008202| steroid metabolic process CYP2E1;CUBN GO:0055114| oxidation-reduction process MTRR;MTHFR;CYP2E1;MMACHC GO:0042493| response to drug CYP2E1;MTHFR 31715:[DB06728 DB08257] DB06728|Aniline KLK1;ALB;CYP2E1 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways GO:0019373| epoxygenase P450 pathway EPHX2;CYP2E1 GO:0017144| drug metabolic process EPHX2;CYP2E1 GO:0006805| xenobiotic metabolic process EPHX2;CYP2E1 31716:[DB06728 DB06626] DB06728|Aniline KLK1;ALB;CYP2E1 DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process FLT4;ALB;KDR GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;UGT1A1;CYP2C19 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP3A5;CYP2C19;UGT1A1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C19 31717:[DB06728 DB04721] DB06728|Aniline KLK1;ALB;CYP2E1 DB04721|N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways 31718:[DB06728 DB07991] DB06728|Aniline KLK1;ALB;CYP2E1 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways 31719:[DB06728 DB06635] DB06728|Aniline KLK1;ALB;CYP2E1 DB06635|Otamixaban F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 31720:[DB06728 DB05298] DB06728|Aniline KLK1;ALB;CYP2E1 DB05298|Tetomilast PDE4D common genes common pathways 31721:[DB06728 DB03328] DB06728|Aniline KLK1;ALB;CYP2E1 DB03328|dioxothiomolybdenum(VI) ion XDH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;XDH 31722:[DB06728 DB07030] DB06728|Aniline KLK1;ALB;CYP2E1 DB07030|(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 31723:[DB06728 DB05562] DB06728|Aniline KLK1;ALB;CYP2E1 DB05562|Naluzotan HTR1A common genes common pathways 31724:[DB06728 DB04339] DB06728|Aniline KLK1;ALB;CYP2E1 DB04339|Carbocisteine GSTP1 common genes common pathways GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0006805| xenobiotic metabolic process GSTP1;CYP2E1 GO:0043066| negative regulation of apoptotic process GSTP1;ALB GO:0098869| ALB;GSTP1 31725:[DB06728 DB05101] DB06728|Aniline KLK1;ALB;CYP2E1 DB05101|Matuzumab EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;ALB 31726:[DB06728 DB07242] DB06728|Aniline KLK1;ALB;CYP2E1 DB07242|(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile DAPK3;PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 31727:[DB06728 DB07508] DB06728|Aniline KLK1;ALB;CYP2E1 DB07508|4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 31728:[DB06728 DB06454] DB06728|Aniline KLK1;ALB;CYP2E1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0045471| response to ethanol DRD2;DRD3;CYP2E1 GO:0042493| response to drug CYP2E1;DRD3;DRD2 31729:[DB06728 DB14126] DB06728|Aniline KLK1;ALB;CYP2E1 DB14126|Tenofovir ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 31730:[DB06728 DB08389] DB06728|Aniline KLK1;ALB;CYP2E1 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 31731:[DB06728 DB00677] DB06728|Aniline KLK1;ALB;CYP2E1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB;TF GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0042493| response to drug CYP2E1;BCHE GO:0043687| post-translational protein modification ALB;TF GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation TF;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis TF;ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31732:[DB06728 DB00136] DB06728|Aniline KLK1;ALB;CYP2E1 DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 31733:[DB06728 DB05806] DB06728|Aniline KLK1;ALB;CYP2E1 DB05806|Cositecan TOP1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 31734:[DB06728 DB04633] DB06728|Aniline KLK1;ALB;CYP2E1 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways 31735:[DB06728 DB13926] DB06728|Aniline KLK1;ALB;CYP2E1 DB13926|Cenegermin NTRK1 common genes common pathways GO:0042493| response to drug CYP2E1;NTRK1 GO:0043066| negative regulation of apoptotic process NTRK1;ALB 31736:[DB06728 DB00776] DB06728|Aniline KLK1;ALB;CYP2E1 DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP3A5 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0002576| platelet degranulation ALB GO:0042493| response to drug UGT1A1;ABCB1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5;CYP2C19 GO:0098869| ALB GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A5;CYP2C19;UGT1A1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 31737:[DB06728 DB11323] DB06728|Aniline KLK1;ALB;CYP2E1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0098869| ALB;PTGS1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 31738:[DB06728 DB03957] DB06728|Aniline KLK1;ALB;CYP2E1 DB03957|SP2456 IL2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IL2 GO:0045471| response to ethanol CYP2E1;IL2 31739:[DB06728 DB14544] DB06728|Aniline KLK1;ALB;CYP2E1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A7;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;ANXA1 GO:0055114| oxidation-reduction process CYP3A5;HSD11B2;HSD3B1;CYP2C8;CYP3A7;CYP11B1;CYP11B2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1;ANXA1;ABCG2;HSD11B2 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A7;CYP11B2;CYP11B1;CYP3A5;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB 31740:[DB06728 DB14481] DB06728|Aniline KLK1;ALB;CYP2E1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes ALB common pathways GO:0044267| cellular protein metabolic process SLC34A1;NUCB1;SLC34A2;ALB;CALB1 GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation CADPS2;ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0042493| response to drug CALR;SLC34A1;SLC8A1;CYP2E1 GO:0043687| post-translational protein modification ALB;NUCB1 GO:0002576| platelet degranulation CALM1;SPARC;ALB GO:0043066| negative regulation of apoptotic process CIB1;ALB;TPT1;RGN GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis SPARC;ALB;CALR GO:0006508| proteolysis PEF1;SRI;GCA;KLK1;PDCD6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol CYP2E1;SPARC 31741:[DB06728 DB06401] DB06728|Aniline KLK1;ALB;CYP2E1 DB06401|Bazedoxifene ESR1;ESR2;UGT1A8;UGT1A10 common genes common pathways GO:0008202| steroid metabolic process UGT1A8;CYP2E1 GO:0017144| drug metabolic process UGT1A8;UGT1A10;CYP2E1 31742:[DB06728 DB08102] DB06728|Aniline KLK1;ALB;CYP2E1 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 31743:[DB06728 DB08030] DB06728|Aniline KLK1;ALB;CYP2E1 DB08030|3-[(4'-cyanobiphenyl-4-yl)oxy]-N-hydroxypropanamide MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 31744:[DB06728 DB07020] DB06728|Aniline KLK1;ALB;CYP2E1 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways 31745:[DB06728 DB05739] DB06728|Aniline KLK1;ALB;CYP2E1 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways GO:0010243| response to organic nitrogen AGTR2;CYP2E1 31746:[DB06728 DB09308] DB06728|Aniline KLK1;ALB;CYP2E1 DB09308|Solithromycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 31747:[DB06728 DB08927] DB06728|Aniline KLK1;ALB;CYP2E1 DB08927|Amperozide HTR2A common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1 31748:[DB06728 DB05966] DB06728|Aniline KLK1;ALB;CYP2E1 DB05966|TAS-108 ESR1;ESR2 common genes common pathways 31749:[DB06728 DB01346] DB06728|Aniline KLK1;ALB;CYP2E1 DB01346|Quinidine barbiturate GABRA1;GABRA2;SCN5A;KCNK1;GRIA2 common genes common pathways 31750:[DB06728 DB00017] DB06728|Aniline KLK1;ALB;CYP2E1 DB00017|Salmon Calcitonin CALCR common genes common pathways 31751:[DB06728 DB07741] DB06728|Aniline KLK1;ALB;CYP2E1 DB07741|4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 31752:[DB06728 DB04200] DB06728|Aniline KLK1;ALB;CYP2E1 DB04200|Matairesinol DHRS4L2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHRS4L2 31753:[DB06728 DB08263] DB06728|Aniline KLK1;ALB;CYP2E1 DB08263|N-(carboxycarbonyl)-D-phenylalanine HIF1AN common genes common pathways GO:0055114| oxidation-reduction process HIF1AN;CYP2E1 31754:[DB06728 DB05266] DB06728|Aniline KLK1;ALB;CYP2E1 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0042493| response to drug CYP2E1;PDE3A 31755:[DB06728 DB08487] DB06728|Aniline KLK1;ALB;CYP2E1 DB08487|3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 31756:[DB06728 DB13757] DB06728|Aniline KLK1;ALB;CYP2E1 DB13757|Epanolol CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 31757:[DB06728 DB07306] DB06728|Aniline KLK1;ALB;CYP2E1 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 31758:[DB06728 DB01071] DB06728|Aniline KLK1;ALB;CYP2E1 DB01071|Mequitazine HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 31759:[DB06728 DB01427] DB06728|Aniline KLK1;ALB;CYP2E1 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0043066| negative regulation of apoptotic process PDE3A;ALB GO:0042493| response to drug CYP2E1;PDE3A 31760:[DB06728 DB00349] DB06728|Aniline KLK1;ALB;CYP2E1 DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP2B6;CYP2C18;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0010243| response to organic nitrogen CYP2E1;SLC6A1 GO:0042493| response to drug GABRG3;CYP2E1;ABCB1;SLC6A11 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C18;CYP2B6;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C18;CYP2E1;CYP2C19;CYP2B6 GO:0017144| drug metabolic process CYP2B6;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2B6 31761:[DB06728 DB05229] DB06728|Aniline KLK1;ALB;CYP2E1 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C8 31762:[DB06728 DB12319] DB06728|Aniline KLK1;ALB;CYP2E1 DB12319|Benzbromarone CYP2C9;CYP2C19;CYP2C19;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP2C9;CYP2C19 GO:0015721| bile acid and bile salt transport SLCO1B1;ABCB11;SLCO2B1;ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C9;CYP2E1 31763:[DB06728 DB05488] DB06728|Aniline KLK1;ALB;CYP2E1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 31764:[DB06728 DB03428] DB06728|Aniline KLK1;ALB;CYP2E1 DB03428|SU9516 CDK5;CDK1;CDK2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CDK1 GO:0042493| response to drug CDK1;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;CDK1 GO:0045471| response to ethanol CYP2E1;CDK1 31765:[DB06728 DB14541] DB06728|Aniline KLK1;ALB;CYP2E1 DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;ANXA1 GO:0042493| response to drug ABCB1;HSD11B2;ANXA1;ABCG2;CYP2E1 GO:0055114| oxidation-reduction process HSD11B2;CYP3A5;HSD3B1;CYP2C8;CYP3A7;CYP11B1;CYP11B2;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1A2;SLC22A8;ALB GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP11B2;CYP11B1;CYP3A7;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 31766:[DB06728 DB05032] DB06728|Aniline KLK1;ALB;CYP2E1 DB05032|REV131 HRH4 common genes common pathways 31767:[DB06728 DB03577] DB06728|Aniline KLK1;ALB;CYP2E1 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways 31768:[DB06728 DB06525] DB06728|Aniline KLK1;ALB;CYP2E1 DB06525|Ganstigmine ACHE common genes common pathways 31769:[DB06728 DB00173] DB06728|Aniline KLK1;ALB;CYP2E1 DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0042493| response to drug CYP2E1;ACACB;UGT1A1 GO:0055114| oxidation-reduction process CYP2E1;PECR 31770:[DB06728 DB00927] DB06728|Aniline KLK1;ALB;CYP2E1 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0008202| steroid metabolic process CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1 31771:[DB06728 DB09006] DB06728|Aniline KLK1;ALB;CYP2E1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0043066| negative regulation of apoptotic process PPARD;ALB GO:0042493| response to drug CYP2E1;PPARG 31772:[DB06728 DB01268] DB06728|Aniline KLK1;ALB;CYP2E1 DB01268|Sunitinib PDGFRB;FLT1;KIT;KDR;FLT4;FLT3;CSF1R;PDGFRA;CYP3A5;CYP3A7;CYP3A4;ABCC4;ABCB1;ABCC2;ABCG2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR;FLT4;PDGFRB;CSF1R GO:0002576| platelet degranulation ALB;ABCC4 GO:0010243| response to organic nitrogen FLT3;CYP2E1;ABCC4 GO:0055114| oxidation-reduction process ABCC4;CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0042493| response to drug ABCG2;ABCC2;ABCB1;ABCC4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0043069| negative regulation of programmed cell death ALB;KIT 31773:[DB06728 DB00979] DB06728|Aniline KLK1;ALB;CYP2E1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 31774:[DB06728 DB07577] DB06728|Aniline KLK1;ALB;CYP2E1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0045471| response to ethanol CYP2E1;TYMS GO:0042493| response to drug TYMS;CYP2E1 31775:[DB06728 DB09318] DB06728|Aniline KLK1;ALB;CYP2E1 DB09318|Synthetic Conjugated Estrogens, B ESR1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31776:[DB06728 DB08604] DB06728|Aniline KLK1;ALB;CYP2E1 DB08604|Triclosan fabI;fabI;fabI;fabI;NR1I2;AR;NR1I3;PPARG;TPO common genes common pathways GO:0098869| TPO;ALB GO:0008202| steroid metabolic process CYP2E1;NR1I2 GO:0055114| oxidation-reduction process TPO;CYP2E1 GO:0042493| response to drug CYP2E1;PPARG GO:0006805| xenobiotic metabolic process CYP2E1;NR1I2 31777:[DB06728 DB07489] DB06728|Aniline KLK1;ALB;CYP2E1 DB07489|4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium CSNK1G3 common genes common pathways 31778:[DB06728 DB02811] DB06728|Aniline KLK1;ALB;CYP2E1 DB02811|Diethylphosphono Group BCHE;fbpC;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 31779:[DB06728 DB00928] DB06728|Aniline KLK1;ALB;CYP2E1 DB00928|Azacitidine DNMT1;CDA common genes common pathways 31780:[DB06728 DB04847] DB06728|Aniline KLK1;ALB;CYP2E1 DB04847|Roxadustat EGLN1;EGLN2;EGLN3 common genes common pathways GO:0055114| oxidation-reduction process EGLN1;EGLN3;EGLN2;CYP2E1 31781:[DB06728 DB09369] DB06728|Aniline KLK1;ALB;CYP2E1 DB09369|Polyestradiol phosphate ESR1 common genes common pathways 31782:[DB06728 DB08734] DB06728|Aniline KLK1;ALB;CYP2E1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug CYP2E1;TYMS GO:0045471| response to ethanol CYP2E1;TYMS 31783:[DB06728 DB09116] DB06728|Aniline KLK1;ALB;CYP2E1 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0043066| negative regulation of apoptotic process CAT;ALB GO:0055114| oxidation-reduction process ALDH3B2;CYP2E1;CAT GO:0042493| response to drug CYP2E1;CAT GO:0098869| ALB;CAT GO:0010193| response to ozone CYP2E1;CAT GO:0045471| response to ethanol CYP2E1;CAT GO:0006641| triglyceride metabolic process CAT;CYP2E1 31784:[DB06728 DB09347] DB06728|Aniline KLK1;ALB;CYP2E1 DB09347|Acetrizoic acid ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 31785:[DB06728 DB09109] DB06728|Aniline KLK1;ALB;CYP2E1 DB09109|Turoctocog alfa F9;F10;F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis KLK1;F2;F10;F9 31786:[DB06728 DB05029] DB06728|Aniline KLK1;ALB;CYP2E1 DB05029|Lancovutide PLA2G4A common genes common pathways 31787:[DB06728 DB00564] DB06728|Aniline KLK1;ALB;CYP2E1 DB00564|Carbamazepine SCN5A;CHRNA4;CHRNB2;NR1I2;CYP3A4;CYP2C8;CYP1A2;CYP2C9;CYP2C19;CYP2B6;CYP3A5;CYP3A7;UGT2B7;UGT1A1;ABCB1;RALBP1;ABCC2 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;CYP2C9;CYP2B6;NR1I2;UGT1A1;UGT2B7;CYP3A4;CYP2E1;CYP3A7;CYP1A2 GO:0042493| response to drug UGT1A1;ABCC2;ABCB1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP2C8;CYP2B6;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP3A5;CYP2B6;NR1I2;CYP2C9;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol UGT1A1;CHRNB2;CYP2E1 31788:[DB06728 DB00262] DB06728|Aniline KLK1;ALB;CYP2E1 DB00262|Carmustine GSR;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0098869| GSR;ALB GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process GSR;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 31789:[DB06728 DB13520] DB06728|Aniline KLK1;ALB;CYP2E1 DB13520|Metergoline SCN2A common genes common pathways 31790:[DB06728 DB08369] DB06728|Aniline KLK1;ALB;CYP2E1 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6 GO:0055114| oxidation-reduction process CYP2E1;CYP2B6 GO:0017144| drug metabolic process CYP2B6;CYP2E1 GO:0008202| steroid metabolic process CYP2B6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2B6 31791:[DB06728 DB08348] DB06728|Aniline KLK1;ALB;CYP2E1 DB08348|N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE EEF2;PARP3;PARP15 common genes common pathways GO:0045471| response to ethanol CYP2E1;EEF2 GO:0042493| response to drug EEF2;CYP2E1 31792:[DB06728 DB07219] DB06728|Aniline KLK1;ALB;CYP2E1 DB07219|BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE CTSB common genes common pathways GO:0006508| proteolysis CTSB;KLK1 31793:[DB06728 DB05876] DB06728|Aniline KLK1;ALB;CYP2E1 DB05876|PDE4 PDE4A common genes common pathways 31794:[DB06728 DB06441] DB06728|Aniline KLK1;ALB;CYP2E1 DB06441|Cangrelor P2RY12 common genes common pathways 31795:[DB06728 DB08645] DB06728|Aniline KLK1;ALB;CYP2E1 DB08645|6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE CA2 common genes common pathways 31796:[DB06728 DB02431] DB06728|Aniline KLK1;ALB;CYP2E1 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways 31797:[DB06728 DB00601] DB06728|Aniline KLK1;ALB;CYP2E1 DB00601|Linezolid MAOA;MAOB common genes common pathways GO:0042493| response to drug CYP2E1;MAOB GO:0055114| oxidation-reduction process MAOA;CYP2E1;MAOB GO:0045471| response to ethanol CYP2E1;MAOB 31798:[DB06728 DB14019] DB06728|Aniline KLK1;ALB;CYP2E1 DB14019|Fosnetupitant CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 31799:[DB06728 DB09059] DB06728|Aniline KLK1;ALB;CYP2E1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0042493| response to drug CYP2E1;OXTR 31800:[DB06728 DB07902] DB06728|Aniline KLK1;ALB;CYP2E1 DB07902|TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE METAP1 common genes common pathways GO:0006508| proteolysis KLK1;METAP1 31801:[DB06728 DB08805] DB06728|Aniline KLK1;ALB;CYP2E1 DB08805|Metiamide HRH2 common genes common pathways 31802:[DB06728 DB01454] DB06728|Aniline KLK1;ALB;CYP2E1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug HTR2C;HTR2B;SLC6A3;SLC6A2;SLC6A4;CYP2E1;HTR2A GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0045471| response to ethanol CYP2E1;SLC6A3 31803:[DB06728 DB00204] DB06728|Aniline KLK1;ALB;CYP2E1 DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 31804:[DB06728 DB05459] DB06728|Aniline KLK1;ALB;CYP2E1 DB05459|Briakinumab IL12B;IL23A common genes common pathways 31805:[DB06728 DB00813] DB06728|Aniline KLK1;ALB;CYP2E1 DB00813|Fentanyl OPRM1;OPRD1;OPRK1;ABCB1;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0042493| response to drug ABCB1;CYP2E1 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 31806:[DB06728 DB13003] DB06728|Aniline KLK1;ALB;CYP2E1 DB13003|Cortivazol NR3C1 common genes common pathways 31807:[DB06728 DB08072] DB06728|Aniline KLK1;ALB;CYP2E1 DB08072|4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 31808:[DB06728 DB00914] DB06728|Aniline KLK1;ALB;CYP2E1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PRKAA1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process PRKAA1;CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 31809:[DB06728 DB03221] DB06728|Aniline KLK1;ALB;CYP2E1 DB03221|AL7099A CA2 common genes common pathways 31810:[DB06728 DB07221] DB06728|Aniline KLK1;ALB;CYP2E1 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways 31811:[DB06728 DB01956] DB06728|Aniline KLK1;ALB;CYP2E1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0045471| response to ethanol GRIN2B;CYP2E1 GO:0042493| response to drug GABRG3;CYP2E1 31812:[DB06728 DB02889] DB06728|Aniline KLK1;ALB;CYP2E1 DB02889|4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose AMY2A;AMY2A common genes common pathways 31813:[DB06728 DB00469] DB06728|Aniline KLK1;ALB;CYP2E1 DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1;PTGS1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1;CYP2C9 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0098869| PTGS2;PTGS1;ALB 31814:[DB06728 DB01780] DB06728|Aniline KLK1;ALB;CYP2E1 DB01780|Fusicoccin YWHAE common genes common pathways 31815:[DB06728 DB04465] DB06728|Aniline KLK1;ALB;CYP2E1 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways 31816:[DB06728 DB01717] DB06728|Aniline KLK1;ALB;CYP2E1 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways 31817:[DB06728 DB07181] DB06728|Aniline KLK1;ALB;CYP2E1 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 31818:[DB06728 DB12887] DB06728|Aniline KLK1;ALB;CYP2E1 DB12887|Tazemetostat EZH2 common genes common pathways 31819:[DB06728 DB04763] DB06728|Aniline KLK1;ALB;CYP2E1 DB04763|1-N-(4-SULFAMOYLPHENYL-ETHYL)-2,4,6-TRIMETHYLPYRIDINIUM CA2 common genes common pathways 31820:[DB06728 DB00620] DB06728|Aniline KLK1;ALB;CYP2E1 DB00620|Triamcinolone NR3C1;CYP3A4;PTGS2;BCHE;SERPINA6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2;BCHE GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0098869| ALB;PTGS2 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 31821:[DB06728 DB11831] DB06728|Aniline KLK1;ALB;CYP2E1 DB11831|Dinitrochlorobenzene MGMT;GSTP1 common genes common pathways GO:0006805| xenobiotic metabolic process GSTP1;CYP2E1 GO:0045471| response to ethanol GSTP1;MGMT;CYP2E1 GO:0042493| response to drug CYP2E1;MGMT GO:0043066| negative regulation of apoptotic process MGMT;GSTP1;ALB GO:0098869| ALB;GSTP1 31822:[DB06728 DB02628] DB06728|Aniline KLK1;ALB;CYP2E1 DB02628|1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process XIAP;ALB 31823:[DB06728 DB05744] DB06728|Aniline KLK1;ALB;CYP2E1 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways GO:0043687| post-translational protein modification ALB;IL6 GO:0042493| response to drug IL10;CYP2E1 GO:0043066| negative regulation of apoptotic process IL6;ALB;IL10 GO:0044267| cellular protein metabolic process IL6;ALB 31824:[DB06728 DB08078] DB06728|Aniline KLK1;ALB;CYP2E1 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways GO:0043066| negative regulation of apoptotic process PPARD;ALB 31825:[DB06728 DB00454] DB06728|Aniline KLK1;ALB;CYP2E1 DB00454|Meperidine OPRK1;GRIN1;GRIN2B;GRIN2A;GRIN2C;GRIN2D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;OPRM1;SLC6A3;SLC6A2;SLC6A4;CES1;CYP3A4;CYP2C19;CYP2B6;CYP2D6;CYP1A2;ALB;ORM1 common genes ALB common pathways GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2B6;CYP2D6;CYP2C19 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2B6;CYP2D6;CYP2C19 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ORM1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2B6;CYP2C19 GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug SLC6A3;SLC6A2;SLC6A4;GRIN2A;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2B6 GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP2B6;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1;CES1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol GRIN2A;OPRM1;GRIN1;CYP2E1;GRIN2B;SLC6A3;OPRK1 31826:[DB06728 DB02866] DB06728|Aniline KLK1;ALB;CYP2E1 DB02866|Dansylamide CA2 common genes common pathways 31827:[DB06728 DB05867] DB06728|Aniline KLK1;ALB;CYP2E1 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 31828:[DB06728 DB12228] DB06728|Aniline KLK1;ALB;CYP2E1 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways 31829:[DB06728 DB00489] DB06728|Aniline KLK1;ALB;CYP2E1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 31830:[DB06728 DB01015] DB06728|Aniline KLK1;ALB;CYP2E1 DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes ALB common pathways GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;UGT1A9;CYP2C8;NAT2;NAT1;GSTP1;CYP3A4;CYP2E1;PTGS1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process PTGS1;CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0008202| steroid metabolic process CYP2C9;CYP2C8;CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A9;CYP2E1;CYP3A4 GO:0098869| PTGS1;GSTP1;ALB 31831:[DB06728 DB05003] DB06728|Aniline KLK1;ALB;CYP2E1 DB05003|Imexon RRM2;RRM1 common genes common pathways GO:0055114| oxidation-reduction process RRM2;RRM1;CYP2E1 31832:[DB06728 DB03667] DB06728|Aniline KLK1;ALB;CYP2E1 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PTGS1 GO:0098869| ALB;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 31833:[DB06728 DB02261] DB06728|Aniline KLK1;ALB;CYP2E1 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 31834:[DB06728 DB02562] DB06728|Aniline KLK1;ALB;CYP2E1 DB02562|Quinonoid 7,8-Tetrahydrobiopterin PAH common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PAH 31835:[DB06728 DB00248] DB06728|Aniline KLK1;ALB;CYP2E1 DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug DRD1;CYP2E1;HTR2A;DRD2;ADRA1A;ABCB1;HTR1B;HTR2C;HTR2B;DRD3 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol DRD3;DRD2;HTR1B;CYP2E1 31836:[DB06728 DB00209] DB06728|Aniline KLK1;ALB;CYP2E1 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 31837:[DB06728 DB00730] DB06728|Aniline KLK1;ALB;CYP2E1 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A1;CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP1A1 31838:[DB06728 DB01963] DB06728|Aniline KLK1;ALB;CYP2E1 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways GO:0006508| proteolysis KLK1;CTRB1 31839:[DB06728 DB03359] DB06728|Aniline KLK1;ALB;CYP2E1 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways 31840:[DB06728 DB04978] DB06728|Aniline KLK1;ALB;CYP2E1 DB04978|SP1049C TOP2A common genes common pathways 31841:[DB06728 DB04419] DB06728|Aniline KLK1;ALB;CYP2E1 DB04419|D-norleucine PTH;HNF1A;PAH common genes common pathways GO:0045471| response to ethanol CYP2E1;PTH GO:0055114| oxidation-reduction process PAH;CYP2E1 GO:0042493| response to drug CYP2E1;PTH 31842:[DB06728 DB05205] DB06728|Aniline KLK1;ALB;CYP2E1 DB05205|CX157 MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 31843:[DB06728 DB00359] DB06728|Aniline KLK1;ALB;CYP2E1 DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0018910| benzene metabolic process CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C9 GO:0010193| response to ozone CYP2E1 31844:[DB06728 DB04090] DB06728|Aniline KLK1;ALB;CYP2E1 DB04090|RH-1 NQO1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;NQO1 GO:0045471| response to ethanol NQO1;CYP2E1 GO:0055114| oxidation-reduction process NQO1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;NQO1 31845:[DB06728 DB08293] DB06728|Aniline KLK1;ALB;CYP2E1 DB08293|(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0043066| negative regulation of apoptotic process HSP90AB1;ALB GO:0042493| response to drug CYP2E1;HSP90AB1 GO:0006805| xenobiotic metabolic process CYP2E1;HSP90AB1 31846:[DB06728 DB00673] DB06728|Aniline KLK1;ALB;CYP2E1 DB00673|Aprepitant TACR1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9 common genes common pathways GO:0010193| response to ozone TACR1;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP2C19;CYP2C9;CYP3A7;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP2C19;CYP3A5;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2C19;CYP3A7;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;TACR1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 31847:[DB06728 DB02132] DB06728|Aniline KLK1;ALB;CYP2E1 DB02132|Zenarestat AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 31848:[DB06728 DB00761] DB06728|Aniline KLK1;ALB;CYP2E1 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0042493| response to drug SLC12A5;CYP2E1 31849:[DB06728 DB04426] DB06728|Aniline KLK1;ALB;CYP2E1 DB04426|Alpha-Methyl-N-Acetyl-D-Glucosamine MBL2 common genes common pathways GO:0006508| proteolysis KLK1;MBL2 31850:[DB06728 DB07251] DB06728|Aniline KLK1;ALB;CYP2E1 DB07251|N'-(3-CHLORO-4-METHOXY-PHENYL)-N-(3,4,5-TRIMETHOXYPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE EPHB4 common genes common pathways 31851:[DB06728 DB04983] DB06728|Aniline KLK1;ALB;CYP2E1 DB04983|Denufosol P2RY2 common genes common pathways 31852:[DB06728 DB06137] DB06728|Aniline KLK1;ALB;CYP2E1 DB06137|KX-01 SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 31853:[DB06728 DB04271] DB06728|Aniline KLK1;ALB;CYP2E1 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways 31854:[DB06728 DB11714] DB06728|Aniline KLK1;ALB;CYP2E1 DB11714|Durvalumab CD274;CD80 common genes common pathways 31855:[DB06728 DB03753] DB06728|Aniline KLK1;ALB;CYP2E1 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process PTGS1;CYP2E1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 31856:[DB06728 DB14025] DB06728|Aniline KLK1;ALB;CYP2E1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2;CYP2C19;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C9 31857:[DB06728 DB14634] DB06728|Aniline KLK1;ALB;CYP2E1 DB14634|Fluprednidene acetate CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31858:[DB06728 DB08455] DB06728|Aniline KLK1;ALB;CYP2E1 DB08455|Ro 12-7310 CRABP2 common genes common pathways 31859:[DB06728 DB04690] DB06728|Aniline KLK1;ALB;CYP2E1 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug TOP1;CYP2E1;ABCB1;ABCG2 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 31860:[DB06728 DB03499] DB06728|Aniline KLK1;ALB;CYP2E1 DB03499|Malate Ion fumC;glcB;ME2;CS common genes common pathways GO:0055114| oxidation-reduction process ME2;CYP2E1 31861:[DB06728 DB02486] DB06728|Aniline KLK1;ALB;CYP2E1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways GO:0098869| ALB;GSTA1 31862:[DB06728 DB06543] DB06728|Aniline KLK1;ALB;CYP2E1 DB06543|Astaxanthin NFKBIA common genes common pathways GO:0043066| negative regulation of apoptotic process NFKBIA;ALB 31863:[DB06728 DB06994] DB06728|Aniline KLK1;ALB;CYP2E1 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 31864:[DB06728 DB07604] DB06728|Aniline KLK1;ALB;CYP2E1 DB07604|(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE ATP2A1 common genes common pathways GO:0051659| maintenance of mitochondrion location ATP2A1;ALB 31865:[DB06728 DB00154] DB06728|Aniline KLK1;ALB;CYP2E1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0098869| PTGS2;PTGS1;ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0042493| response to drug PTGS2;CYP2E1 31866:[DB06728 DB12278] DB06728|Aniline KLK1;ALB;CYP2E1 DB12278|Propiverine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CACNA1C;ADRA1A;CYP3A4;FMO1;FMO3;CYP2B common genes common pathways GO:0017144| drug metabolic process CYP2E1;FMO1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ADRA1A GO:0055114| oxidation-reduction process FMO3;CYP3A4;FMO1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;FMO1;FMO3 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 31867:[DB06728 DB00221] DB06728|Aniline KLK1;ALB;CYP2E1 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 31868:[DB06728 DB05227] DB06728|Aniline KLK1;ALB;CYP2E1 DB05227|APD791 HTR2A common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1 31869:[DB06728 DB03487] DB06728|Aniline KLK1;ALB;CYP2E1 DB03487|3-Aminosuccinimide LYZ common genes common pathways GO:0044267| cellular protein metabolic process LYZ;ALB GO:0001895| retina homeostasis ALB;LYZ 31870:[DB06728 DB08908] DB06728|Aniline KLK1;ALB;CYP2E1 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RELA GO:0042493| response to drug CYP2E1;RELA GO:0043687| post-translational protein modification ALB;KEAP1 31871:[DB06728 DB05104] DB06728|Aniline KLK1;ALB;CYP2E1 DB05104|Asimadoline OPRK1 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRK1 31872:[DB06728 DB09071] DB06728|Aniline KLK1;ALB;CYP2E1 DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 31873:[DB06728 DB04297] DB06728|Aniline KLK1;ALB;CYP2E1 DB04297|7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide HDAC8;HDAC7 common genes common pathways 31874:[DB06728 DB06841] DB06728|Aniline KLK1;ALB;CYP2E1 DB06841|D-phenylalanyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl)butyl]-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 31875:[DB06728 DB02090] DB06728|Aniline KLK1;ALB;CYP2E1 DB02090|A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 31876:[DB06728 DB05013] DB06728|Aniline KLK1;ALB;CYP2E1 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways 31877:[DB06728 DB04803] DB06728|Aniline KLK1;ALB;CYP2E1 DB04803|Verdoheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP2E1 31878:[DB06728 DB00712] DB06728|Aniline KLK1;ALB;CYP2E1 DB00712|Flurbiprofen PTGS1;PTGS2;CYP2C9;UGT2B7;UGT1A1;UGT1A3;UGT1A9;UGT2B4;ALB;ABCC4;SLC22A6 common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1;ABCC4;CYP2C9 GO:0042493| response to drug UGT1A1;ABCC4;CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1;ABCC4 GO:0002576| platelet degranulation ALB;ABCC4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0008202| steroid metabolic process CYP2E1;UGT2B7;UGT1A1;CYP2C9 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2C9;UGT1A3;CYP2E1 GO:0098869| PTGS2;PTGS1;ALB GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process UGT1A9;UGT2B4;CYP2C9;PTGS1;CYP2E1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB 31879:[DB06728 DB05706] DB06728|Aniline KLK1;ALB;CYP2E1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways 31880:[DB06728 DB04487] DB06728|Aniline KLK1;ALB;CYP2E1 DB04487|N-Methylleucine CXCL10 common genes common pathways 31881:[DB06728 DB08167] DB06728|Aniline KLK1;ALB;CYP2E1 DB08167|Methylthioninium ACHE common genes common pathways 31882:[DB06728 DB06075] DB06728|Aniline KLK1;ALB;CYP2E1 DB06075|Linsitinib IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IGF1R 31883:[DB06728 DB11584] DB06728|Aniline KLK1;ALB;CYP2E1 DB11584|Pipradrol DRD1;DRD5 common genes common pathways GO:0042493| response to drug DRD1;CYP2E1 31884:[DB06728 DB08658] DB06728|Aniline KLK1;ALB;CYP2E1 DB08658|ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 31885:[DB06728 DB02221] DB06728|Aniline KLK1;ALB;CYP2E1 DB02221|4-(Aminosulfonyl)-N-[(2,4,6-Trifluorophenyl)Methyl]-Benzamide CA2 common genes common pathways 31886:[DB06728 DB05492] DB06728|Aniline KLK1;ALB;CYP2E1 DB05492|Epicept NP-1 OPRM1;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;OPRL1 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1 GO:0042493| response to drug HTR2B;HTR2C;ADRA1A;CYP2E1;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;ALB 31887:[DB06728 DB02498] DB06728|Aniline KLK1;ALB;CYP2E1 DB02498|Carba-Nicotinamide-Adenine-Dinucleotide PARP1 common genes common pathways 31888:[DB06728 DB02123] DB06728|Aniline KLK1;ALB;CYP2E1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0015721| bile acid and bile salt transport ABCB11;SLCO1A2;ALB;SLC10A2;SLC10A1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 31889:[DB06728 DB05890] DB06728|Aniline KLK1;ALB;CYP2E1 DB05890|VEGF-AS VEGFA common genes common pathways GO:0043066| negative regulation of apoptotic process VEGFA;ALB GO:0002576| platelet degranulation ALB;VEGFA 31890:[DB06728 DB07779] DB06728|Aniline KLK1;ALB;CYP2E1 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 31891:[DB06728 DB06335] DB06728|Aniline KLK1;ALB;CYP2E1 DB06335|Saxagliptin DPP4;CYP3A4;CYP3A5;ABCC1;SLCO4C1;SLC22A8 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug ABCC1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLCO4C1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5 31892:[DB06728 DB12328] DB06728|Aniline KLK1;ALB;CYP2E1 DB12328|Cantharidin AHR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;AHR 31893:[DB06728 DB08043] DB06728|Aniline KLK1;ALB;CYP2E1 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways 31894:[DB06728 DB00034] DB06728|Aniline KLK1;ALB;CYP2E1 DB00034|Interferon Alfa-2a, Recombinant IFNAR1;IFNAR2 common genes common pathways 31895:[DB06728 DB00817] DB06728|Aniline KLK1;ALB;CYP2E1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 31896:[DB06728 DB07623] DB06728|Aniline KLK1;ALB;CYP2E1 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2A6 GO:0008202| steroid metabolic process CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1 GO:0055114| oxidation-reduction process CYP2A6;CYP2E1 31897:[DB06728 DB07524] DB06728|Aniline KLK1;ALB;CYP2E1 DB07524|N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;ALB 31898:[DB06728 DB07248] DB06728|Aniline KLK1;ALB;CYP2E1 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways GO:0043066| negative regulation of apoptotic process PTK2;ALB 31899:[DB06728 DB02778] DB06728|Aniline KLK1;ALB;CYP2E1 DB02778|2,5-Anhydroglucitol-1,6-Biphosphate FBP1 common genes common pathways 31900:[DB06728 DB00900] DB06728|Aniline KLK1;ALB;CYP2E1 DB00900|Didanosine pol;PNP;ALB;SLC22A6;SLC29A1;SLC29A2 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0098869| ALB GO:0042493| response to drug CYP2E1;PNP GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 31901:[DB06728 DB03951] DB06728|Aniline KLK1;ALB;CYP2E1 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 31902:[DB06728 DB05319] DB06728|Aniline KLK1;ALB;CYP2E1 DB05319|Oportuzumab monatox EPCAM common genes common pathways 31903:[DB06728 DB02812] DB06728|Aniline KLK1;ALB;CYP2E1 DB02812|(2s,4r)-1-Acetyl-N-[(1s)-4-[(Aminoiminomethyl)Amino]-1-(2-Benzothiazolylcarbonyl)Butyl]-4-Hydroxy-2-Pyrrolidinecarboxamide PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 31904:[DB06728 DB07254] DB06728|Aniline KLK1;ALB;CYP2E1 DB07254|N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL]AMINO]PHENYL]METHANESULFONAMIDE EPHB4 common genes common pathways 31905:[DB06728 DB09076] DB06728|Aniline KLK1;ALB;CYP2E1 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 31906:[DB06728 DB08804] DB06728|Aniline KLK1;ALB;CYP2E1 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0042493| response to drug CYP2E1;MAOB GO:0055114| oxidation-reduction process CYP19A1;MAOB;CYP2E1;MAOA 31907:[DB06728 DB08516] DB06728|Aniline KLK1;ALB;CYP2E1 DB08516|(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] MAOB common genes common pathways GO:0042493| response to drug MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOB;CYP2E1 GO:0045471| response to ethanol MAOB;CYP2E1 31908:[DB06728 DB00665] DB06728|Aniline KLK1;ALB;CYP2E1 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C19;CYP2C8;POR GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2E1 GO:0043066| negative regulation of apoptotic process POR;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0042493| response to drug CYP2E1;POR GO:0055114| oxidation-reduction process POR;CYP2C19;CYP2C8;CYP2E1 31909:[DB06728 DB01342] DB06728|Aniline KLK1;ALB;CYP2E1 DB01342|Forasartan AGTR1 common genes common pathways 31910:[DB06728 DB05049] DB06728|Aniline KLK1;ALB;CYP2E1 DB05049|DDP733 HTR3A common genes common pathways GO:0045471| response to ethanol HTR3A;CYP2E1 31911:[DB06728 DB07821] DB06728|Aniline KLK1;ALB;CYP2E1 DB07821|(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate CES1;PAFAH1B3;PLA2G7 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 31912:[DB06728 DB03553] DB06728|Aniline KLK1;ALB;CYP2E1 DB03553|Glutaric Acid ilvE;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6;SLC22A11;SLC22A7;SLC22A8 31913:[DB06728 DB00977] DB06728|Aniline KLK1;ALB;CYP2E1 DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process NR1I2;CYP2C8;CYP3A4;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;UGT1A1;ABCC2;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLC10A1;ABCB11 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;NR1I2;CYP2E1;CYP3A4 31914:[DB06728 DB00246] DB06728|Aniline KLK1;ALB;CYP2E1 DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug DRD1;CYP2E1;HTR2A;CYP1A2;HTR2C;HTR1B;DRD2;ADRA1A;DRD3 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1;DRD3;HTR1B;DRD2;HTR3A GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A5;CYP3A4;CYP2E1;CYP3A7;CYP1A2 31915:[DB06728 DB07900] DB06728|Aniline KLK1;ALB;CYP2E1 DB07900|3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE MMP8 common genes common pathways GO:0006508| proteolysis KLK1;MMP8 31916:[DB06728 DB00907] DB06728|Aniline KLK1;ALB;CYP2E1 DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C8;CYP3A7;CYP3A4;CYP2E1;CES1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2D6;CYP2C8 GO:0042493| response to drug SLC6A4;SCN11A;CYP2E1;SLC6A3;BCHE;SLC6A2 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2D6;CYP3A7;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2C8;CYP3A4;CYP2E1 31917:[DB06728 DB00605] DB06728|Aniline KLK1;ALB;CYP2E1 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process AKR1B10;CYP1A1;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0098869| PTGS2;PTGS1;ALB GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0042493| response to drug CYP1A1;CYP2E1;PTGS2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1;AKR1B10;AKR1B1;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PPARD;PTGS2;ALB;AKR1B1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0002576| platelet degranulation ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 31918:[DB06728 DB03796] DB06728|Aniline KLK1;ALB;CYP2E1 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C8;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP2C8 GO:0042493| response to drug FABP3;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0043066| negative regulation of apoptotic process PPT1;ALB GO:0002576| platelet degranulation ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB;PPT1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31919:[DB06728 DB07847] DB06728|Aniline KLK1;ALB;CYP2E1 DB07847|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 31920:[DB06728 DB05187] DB06728|Aniline KLK1;ALB;CYP2E1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PPARD 31921:[DB06728 DB05838] DB06728|Aniline KLK1;ALB;CYP2E1 DB05838|OPC-51803 AVPR2 common genes common pathways 31922:[DB06728 DB03107] DB06728|Aniline KLK1;ALB;CYP2E1 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways 31923:[DB06728 DB07026] DB06728|Aniline KLK1;ALB;CYP2E1 DB07026|(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE MMP12 common genes common pathways GO:0006508| proteolysis MMP12;KLK1 31924:[DB06728 DB01355] DB06728|Aniline KLK1;ALB;CYP2E1 DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes CYP2E1 common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2C19;CYP2E1;CYP3A4;PTGS1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C19 GO:0018910| benzene metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19 31925:[DB06728 DB03729] DB06728|Aniline KLK1;ALB;CYP2E1 DB03729|2-Amino-5-Hydroxy-Benzimidazole PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 31926:[DB06728 DB07270] DB06728|Aniline KLK1;ALB;CYP2E1 DB07270|N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE FBP1 common genes common pathways 31927:[DB06728 DB04454] DB06728|Aniline KLK1;ALB;CYP2E1 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways GO:0002576| platelet degranulation EGF;ALB 31928:[DB06728 DB00754] DB06728|Aniline KLK1;ALB;CYP2E1 DB00754|Ethotoin SCN5A;NR1I2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;NR1I2 GO:0008202| steroid metabolic process CYP2E1;NR1I2 31929:[DB06728 DB02705] DB06728|Aniline KLK1;ALB;CYP2E1 DB02705|6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 31930:[DB06728 DB04775] DB06728|Aniline KLK1;ALB;CYP2E1 DB04775|Reidispongiolide C ACTA1 common genes common pathways 31931:[DB06728 DB06080] DB06728|Aniline KLK1;ALB;CYP2E1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR;FLT4;CSF1R GO:0010243| response to organic nitrogen CYP2E1;FLT3 GO:0043069| negative regulation of programmed cell death KIT;ALB 31932:[DB06728 DB00651] DB06728|Aniline KLK1;ALB;CYP2E1 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0044267| cellular protein metabolic process ALB;ADORA2A GO:0042493| response to drug CYP2E1;ADORA2A GO:0043066| negative regulation of apoptotic process ADORA1;ALB 31933:[DB06728 DB06230] DB06728|Aniline KLK1;ALB;CYP2E1 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 GO:0008202| steroid metabolic process UGT2B7;CYP2E1;UGT1A8 GO:0017144| drug metabolic process UGT1A8;UGT1A3;CYP2E1 31934:[DB06728 DB06642] DB06728|Aniline KLK1;ALB;CYP2E1 DB06642|Bevasiranib VEGFA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;VEGFA GO:0002576| platelet degranulation ALB;VEGFA 31935:[DB06728 DB11182] DB06728|Aniline KLK1;ALB;CYP2E1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes ALB common pathways GO:0044267| cellular protein metabolic process TF;LTF;LYZ;ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB;TF GO:0002576| platelet degranulation TF;ALB GO:0043066| negative regulation of apoptotic process LTF;ALB GO:0001895| retina homeostasis TF;LTF;LYZ;ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006508| proteolysis LTF;KLK1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 31936:[DB06728 DB08708] DB06728|Aniline KLK1;ALB;CYP2E1 DB08708|N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;ALB 31937:[DB06728 DB07482] DB06728|Aniline KLK1;ALB;CYP2E1 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 31938:[DB06728 DB03940] DB06728|Aniline KLK1;ALB;CYP2E1 DB03940|Oxamic Acid LDHA;LDHB;SLC16A3 common genes common pathways GO:0042493| response to drug LDHA;CYP2E1 GO:0055114| oxidation-reduction process LDHB;LDHA;CYP2E1 31939:[DB06728 DB04770] DB06728|Aniline KLK1;ALB;CYP2E1 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways 31940:[DB06728 DB06709] DB06728|Aniline KLK1;ALB;CYP2E1 DB06709|Methacholine CHRM3 common genes common pathways 31941:[DB06728 DB04014] DB06728|Aniline KLK1;ALB;CYP2E1 DB04014|Alsterpaullone CDK5;CDK1;GSK3B common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CDK1;GSK3B GO:0010243| response to organic nitrogen CYP2E1;CDK1 GO:0042493| response to drug CYP2E1;CDK1 GO:0045471| response to ethanol CYP2E1;CDK1 31942:[DB06728 DB02532] DB06728|Aniline KLK1;ALB;CYP2E1 DB02532|2,4,6-Triaminoquinazoline DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHRS4L1 31943:[DB06728 DB00457] DB06728|Aniline KLK1;ALB;CYP2E1 DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0042493| response to drug CYP1A1;ABCG2;ADRA1A;ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A1 GO:0002576| platelet degranulation ORM1;ALB GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 31944:[DB06728 DB06813] DB06728|Aniline KLK1;ALB;CYP2E1 DB06813|Pralatrexate DHFR;TYMS;FPGS;SLC19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR GO:0042493| response to drug TYMS;CYP2E1 GO:0045471| response to ethanol TYMS;CYP2E1 31945:[DB06728 DB09048] DB06728|Aniline KLK1;ALB;CYP2E1 DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;TACR1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6 GO:0055114| oxidation-reduction process CYP3A43;CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0010193| response to ozone TACR1;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP3A4;CYP2E1 31946:[DB06728 DB08339] DB06728|Aniline KLK1;ALB;CYP2E1 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways 31947:[DB06728 DB05362] DB06728|Aniline KLK1;ALB;CYP2E1 DB05362|SSR-126517E F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 31948:[DB06728 DB05069] DB06728|Aniline KLK1;ALB;CYP2E1 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways 31949:[DB06728 DB02243] DB06728|Aniline KLK1;ALB;CYP2E1 DB02243|4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide CTSF common genes common pathways GO:0006508| proteolysis KLK1;CTSF 31950:[DB06728 DB14007] DB06728|Aniline KLK1;ALB;CYP2E1 DB14007|Pentetic acid SERPINA1 common genes common pathways GO:0044267| cellular protein metabolic process SERPINA1;ALB GO:0043687| post-translational protein modification ALB;SERPINA1 GO:0002576| platelet degranulation SERPINA1;ALB 31951:[DB06728 DB08526] DB06728|Aniline KLK1;ALB;CYP2E1 DB08526|CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE CTSH common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CTSH GO:0044267| cellular protein metabolic process CTSH;ALB GO:0006508| proteolysis CTSH;KLK1 31952:[DB06728 DB06956] DB06728|Aniline KLK1;ALB;CYP2E1 DB06956|N-(4-ACETYLPHENYL)-5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 31953:[DB06728 DB06229] DB06728|Aniline KLK1;ALB;CYP2E1 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1;HTR2B;HTR2C;ADRA1A;DRD2 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0045471| response to ethanol CYP2E1;DRD2 31954:[DB06728 DB04018] DB06728|Aniline KLK1;ALB;CYP2E1 DB04018|S-Isopropyl-Isothiourea NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 31955:[DB06728 DB02551] DB06728|Aniline KLK1;ALB;CYP2E1 DB02551|6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 31956:[DB06728 DB05630] DB06728|Aniline KLK1;ALB;CYP2E1 DB05630|Sodium stibogluconate TOP1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 31957:[DB06728 DB07056] DB06728|Aniline KLK1;ALB;CYP2E1 DB07056|2-(6-{[(3-chloro-2-methylphenyl)sulfonyl]amino}pyridin-2-yl)-N,N-diethylacetamide HSD11B1 common genes common pathways GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 GO:0008202| steroid metabolic process HSD11B1;CYP2E1 31958:[DB06728 DB02527] DB06728|Aniline KLK1;ALB;CYP2E1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0002576| platelet degranulation ALB;ABCC4 GO:0055114| oxidation-reduction process ABCC4;CYP2E1 GO:0042493| response to drug ABCC4;CYP2E1 GO:0010243| response to organic nitrogen ABCC4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLC22A7 31959:[DB06728 DB09216] DB06728|Aniline KLK1;ALB;CYP2E1 DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;PTGS2 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| PTGS2;PTGS1;ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process PTGS1;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 31960:[DB06728 DB03536] DB06728|Aniline KLK1;ALB;CYP2E1 DB03536|Benzoyl-Arginine-Alanine-Methyl Ketone CTSF common genes common pathways GO:0006508| proteolysis KLK1;CTSF 31961:[DB06728 DB00820] DB06728|Aniline KLK1;ALB;CYP2E1 DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A5;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5 31962:[DB06728 DB07954] DB06728|Aniline KLK1;ALB;CYP2E1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways 31963:[DB06728 DB04795] DB06728|Aniline KLK1;ALB;CYP2E1 DB04795|Thenoyltrifluoroacetone CES1;SDHA common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CES1 GO:0055114| oxidation-reduction process CYP2E1;SDHA 31964:[DB06728 DB11363] DB06728|Aniline KLK1;ALB;CYP2E1 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;CYP2E1 31965:[DB06728 DB05168] DB06728|Aniline KLK1;ALB;CYP2E1 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;FOLR1;FOLR2 31966:[DB06728 DB08889] DB06728|Aniline KLK1;ALB;CYP2E1 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways GO:0010243| response to organic nitrogen PSMB2;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 GO:0043687| post-translational protein modification ALB;PSMB8;PSMB10;PSMB5;PSMB1;PSMB2;PSMB9 GO:0006508| proteolysis PSMB8;PSMB9;PSMB2;PSMB1;PSMB5;KLK1;PSMB10 31967:[DB06728 DB00984] DB06728|Aniline KLK1;ALB;CYP2E1 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP19A1 31968:[DB06728 DB11605] DB06728|Aniline KLK1;ALB;CYP2E1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0015721| bile acid and bile salt transport NR1H4;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5;NR1I2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A7;CYP3A43;CYP3A5 GO:0043066| negative regulation of apoptotic process NR1H4;ALB GO:0006805| xenobiotic metabolic process NR1I2;CYP3A5;CYP3A7;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 31969:[DB06728 DB08602] DB06728|Aniline KLK1;ALB;CYP2E1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways 31970:[DB06728 DB00522] DB06728|Aniline KLK1;ALB;CYP2E1 DB00522|Bentiromide HPN common genes common pathways GO:0006508| proteolysis HPN;KLK1 GO:0043066| negative regulation of apoptotic process HPN;ALB 31971:[DB06728 DB02004] DB06728|Aniline KLK1;ALB;CYP2E1 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 31972:[DB06728 DB00687] DB06728|Aniline KLK1;ALB;CYP2E1 DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 31973:[DB06728 DB09301] DB06728|Aniline KLK1;ALB;CYP2E1 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;GDNF;VEGFA GO:0002576| platelet degranulation ALB;VEGFA GO:0043687| post-translational protein modification ARSB;ALB GO:0044267| cellular protein metabolic process HEXB;ALB 31974:[DB06728 DB01137] DB06728|Aniline KLK1;ALB;CYP2E1 DB01137|Levofloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;ABCB1;SLC22A6;SLC22A2;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2 31975:[DB06728 DB08771] DB06728|Aniline KLK1;ALB;CYP2E1 DB08771|(5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1,3-thiazol-4(5H)-one HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1 GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 31976:[DB06728 DB05047] DB06728|Aniline KLK1;ALB;CYP2E1 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways 31977:[DB06728 DB07614] DB06728|Aniline KLK1;ALB;CYP2E1 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways 31978:[DB06728 DB07838] DB06728|Aniline KLK1;ALB;CYP2E1 DB07838|(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE NMT2 common genes common pathways 31979:[DB06728 DB00876] DB06728|Aniline KLK1;ALB;CYP2E1 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC2 31980:[DB06728 DB04126] DB06728|Aniline KLK1;ALB;CYP2E1 DB04126|N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-2-Methyl-Butane CTSB;CTSH common genes common pathways GO:0006508| proteolysis CTSH;CTSB;KLK1 GO:0044267| cellular protein metabolic process ALB;CTSH GO:0043066| negative regulation of apoptotic process ALB;CTSH 31981:[DB06728 DB07636] DB06728|Aniline KLK1;ALB;CYP2E1 DB07636|5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE MT-CYB;UQCRFS1;CYC1;UQCRB;UQCR10 common genes common pathways GO:0045471| response to ethanol MT-CYB;CYP2E1 GO:0010243| response to organic nitrogen MT-CYB;CYP2E1 GO:0042493| response to drug MT-CYB;UQCRFS1;CYP2E1 GO:0055114| oxidation-reduction process UQCR10;UQCRFS1;CYP2E1;UQCRB;CYC1;MT-CYB 31982:[DB06728 DB05316] DB06728|Aniline KLK1;ALB;CYP2E1 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0042493| response to drug DRD2;HTR2A;CYP2E1 GO:0045471| response to ethanol DRD2;CYP2E1 31983:[DB06728 DB05607] DB06728|Aniline KLK1;ALB;CYP2E1 DB05607|PRX-08066 HTR2B common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0042493| response to drug HTR2B;CYP2E1 31984:[DB06728 DB03955] DB06728|Aniline KLK1;ALB;CYP2E1 DB03955|1-deoxymannojirimycin MAN2A1 common genes common pathways 31985:[DB06728 DB01414] DB06728|Aniline KLK1;ALB;CYP2E1 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A6;ALB 31986:[DB06728 DB08647] DB06728|Aniline KLK1;ALB;CYP2E1 DB08647|TRAZEOLIDE IGKC common genes common pathways GO:0006898| receptor-mediated endocytosis IGKC;ALB GO:0001895| retina homeostasis IGKC;ALB GO:0006508| proteolysis KLK1;IGKC 31987:[DB06728 DB02935] DB06728|Aniline KLK1;ALB;CYP2E1 DB02935|Diglyme HSP90B1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90B1;ALB GO:0043687| post-translational protein modification HSP90B1;ALB GO:0043066| negative regulation of apoptotic process HSP90B1;ALB GO:0044267| cellular protein metabolic process ALB;HSP90B1 31988:[DB06728 DB07050] DB06728|Aniline KLK1;ALB;CYP2E1 DB07050|5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide CA2 common genes common pathways 31989:[DB06728 DB03125] DB06728|Aniline KLK1;ALB;CYP2E1 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 31990:[DB06728 DB01192] DB06728|Aniline KLK1;ALB;CYP2E1 DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0045471| response to ethanol OPRM1;CYP2E1 31991:[DB06728 DB08861] DB06728|Aniline KLK1;ALB;CYP2E1 DB08861|DPDPE SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO1B3;ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;ALB 31992:[DB06728 DB00339] DB06728|Aniline KLK1;ALB;CYP2E1 DB00339|Pyrazinamide XDH;AOX1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process AOX1;XDH;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process AOX1;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 31993:[DB06728 DB02140] DB06728|Aniline KLK1;ALB;CYP2E1 DB02140|N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide CTSH common genes common pathways GO:0006508| proteolysis CTSH;KLK1 GO:0044267| cellular protein metabolic process ALB;CTSH GO:0043066| negative regulation of apoptotic process CTSH;ALB 31994:[DB06728 DB04743] DB06728|Aniline KLK1;ALB;CYP2E1 DB04743|Nimesulide PTGS2;PLA2G2E;LTF;CYP3A4 common genes common pathways GO:0001895| retina homeostasis LTF;ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0006508| proteolysis KLK1;LTF GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0098869| PTGS2;ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0044267| cellular protein metabolic process ALB;LTF GO:0043066| negative regulation of apoptotic process ALB;PTGS2;LTF GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 31995:[DB06728 DB04714] DB06728|Aniline KLK1;ALB;CYP2E1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0008202| steroid metabolic process CYP2E1;FDPS 31996:[DB06728 DB06979] DB06728|Aniline KLK1;ALB;CYP2E1 DB06979|5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid HAO1 common genes common pathways GO:0055114| oxidation-reduction process HAO1;CYP2E1 31997:[DB06728 DB09477] DB06728|Aniline KLK1;ALB;CYP2E1 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways GO:0006508| proteolysis ACE;KLK1 31998:[DB06728 DB08402] DB06728|Aniline KLK1;ALB;CYP2E1 DB08402|2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID PPARG;NCOA2;RXRA common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB GO:0042493| response to drug CYP2E1;PPARG 31999:[DB06728 DB08795] DB06728|Aniline KLK1;ALB;CYP2E1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 32000:[DB06728 DB06930] DB06728|Aniline KLK1;ALB;CYP2E1 DB06930|N-[amino(imino)methyl]-2-(2,5-diphenyl-1H-pyrrol-1-yl)acetamide BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis KLK1;BACE1 32001:[DB06728 DB07340] DB06728|Aniline KLK1;ALB;CYP2E1 DB07340|N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine AURKB;INCENP common genes common pathways 32002:[DB06728 DB09240] DB06728|Aniline KLK1;ALB;CYP2E1 DB09240|Niludipine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32003:[DB06728 DB13421] DB06728|Aniline KLK1;ALB;CYP2E1 DB13421|Edoxudine ALB common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 32004:[DB06728 DB12023] DB06728|Aniline KLK1;ALB;CYP2E1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways 32005:[DB06728 DB13879] DB06728|Aniline KLK1;ALB;CYP2E1 DB13879|Glecaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A7;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0042493| response to drug ABCG2;ABCB1;UGT1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP3A43;CYP3A5 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5;UGT1A1 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB 32006:[DB06728 DB05423] DB06728|Aniline KLK1;ALB;CYP2E1 DB05423|ORG-34517 NR3C1 common genes common pathways 32007:[DB06728 DB06898] DB06728|Aniline KLK1;ALB;CYP2E1 DB06898|4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 32008:[DB06728 DB04477] DB06728|Aniline KLK1;ALB;CYP2E1 DB04477|N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process GAPDHS;CYP2E1 32009:[DB06728 DB05415] DB06728|Aniline KLK1;ALB;CYP2E1 DB05415|OSI-461 PDE5A common genes common pathways 32010:[DB06728 DB00571] DB06728|Aniline KLK1;ALB;CYP2E1 DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A7;MAOA;CYP1A2;CYP3A4;CYP2E1;CYP1A1;CYP3A5;CYP2D6;CYP2C19 GO:0042493| response to drug CYP2E1;CYP1A2;CYP1A1;ABCB1;HTR1B GO:0002576| platelet degranulation ALB;ORM1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C19;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A1;CYP3A5;CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP3A7;CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0045471| response to ethanol CYP2E1;HTR1B GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB 32011:[DB06728 DB04618] DB06728|Aniline KLK1;ALB;CYP2E1 DB04618|4,6-DIDEOXY-4-{[4-[(4-O-HEXOPYRANOSYLHEXOPYRANOSYL)OXY]-5,6-DIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}HEXOPYRANOSYL-(1->4)HEXOPYRANOSYL-(1->4)HEXOPYRANOSE AMY2A common genes common pathways 32012:[DB06728 DB00431] DB06728|Aniline KLK1;ALB;CYP2E1 DB00431|Lindane GABRB1;GLRA1;GLRA2;GLRA3;GLRB;GABRB3;GABRR1;PGR;ESR1;NR1I2 common genes common pathways GO:0008202| steroid metabolic process NR1I2;CYP2E1 GO:0006805| xenobiotic metabolic process NR1I2;CYP2E1 32013:[DB06728 DB06896] DB06728|Aniline KLK1;ALB;CYP2E1 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways 32014:[DB06728 DB03981] DB06728|Aniline KLK1;ALB;CYP2E1 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways GO:0002576| platelet degranulation ANXA5;ALB GO:0043066| negative regulation of apoptotic process ALB;ANXA5 32015:[DB06728 DB07736] DB06728|Aniline KLK1;ALB;CYP2E1 DB07736|(2S)-4-(4-fluorobenzyl)-N-(2-sulfanylethyl)piperazine-2-carboxamide BACE1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;BACE1 GO:0006508| proteolysis BACE1;KLK1 32016:[DB06728 DB07968] DB06728|Aniline KLK1;ALB;CYP2E1 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways 32017:[DB06728 DB03987] DB06728|Aniline KLK1;ALB;CYP2E1 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 32018:[DB06728 DB04076] DB06728|Aniline KLK1;ALB;CYP2E1 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2;PNP GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 32019:[DB06728 DB06512] DB06728|Aniline KLK1;ALB;CYP2E1 DB06512|Deramciclane HTR2A;HTR2C;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0042493| response to drug HTR2A;CYP2E1;HTR2C 32020:[DB06728 DB07403] DB06728|Aniline KLK1;ALB;CYP2E1 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways 32021:[DB06728 DB05971] DB06728|Aniline KLK1;ALB;CYP2E1 DB05971|Archexin AKT1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKT1;ALB 32022:[DB06728 DB02996] DB06728|Aniline KLK1;ALB;CYP2E1 DB02996|2-(Thiomethylene)-4-Methylpentanoic Acid ADAM28 common genes common pathways GO:0006508| proteolysis KLK1;ADAM28 32023:[DB06728 DB12629] DB06728|Aniline KLK1;ALB;CYP2E1 DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32024:[DB06728 DB06240] DB06728|Aniline KLK1;ALB;CYP2E1 DB06240|Tariquidar ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 32025:[DB06728 DB07665] DB06728|Aniline KLK1;ALB;CYP2E1 DB07665|N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 32026:[DB06728 DB03821] DB06728|Aniline KLK1;ALB;CYP2E1 DB03821|2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid ARSA;ARSA common genes common pathways GO:0043687| post-translational protein modification ARSA;ALB 32027:[DB06728 DB00806] DB06728|Aniline KLK1;ALB;CYP2E1 DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2;ADORA2A 32028:[DB06728 DB08303] DB06728|Aniline KLK1;ALB;CYP2E1 DB08303|(3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide GRIA2 common genes common pathways 32029:[DB06728 DB07999] DB06728|Aniline KLK1;ALB;CYP2E1 DB07999|{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 32030:[DB06728 DB04470] DB06728|Aniline KLK1;ALB;CYP2E1 DB04470|CRA_10656 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32031:[DB06728 DB01273] DB06728|Aniline KLK1;ALB;CYP2E1 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways GO:0045471| response to ethanol CYP2E1;CHRNB2 32032:[DB06728 DB08856] DB06728|Aniline KLK1;ALB;CYP2E1 DB08856|DADLE SLCO1B1 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0015721| bile acid and bile salt transport SLCO1B1;ALB 32033:[DB06728 DB07447] DB06728|Aniline KLK1;ALB;CYP2E1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;AKR1D1 GO:0055114| oxidation-reduction process AKR1D1;CYP2E1 32034:[DB06728 DB08729] DB06728|Aniline KLK1;ALB;CYP2E1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways 32035:[DB06728 DB09037] DB06728|Aniline KLK1;ALB;CYP2E1 DB09037|Pembrolizumab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PDCD1 32036:[DB06728 DB11752] DB06728|Aniline KLK1;ALB;CYP2E1 DB11752|Bryostatin 1 CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 32037:[DB06728 DB00498] DB06728|Aniline KLK1;ALB;CYP2E1 DB00498|Phenindione VKORC1 common genes common pathways GO:0055114| oxidation-reduction process VKORC1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;VKORC1 32038:[DB06728 DB03194] DB06728|Aniline KLK1;ALB;CYP2E1 DB03194|beta-L-methyl-fucose MBL2 common genes common pathways GO:0006508| proteolysis MBL2;KLK1 32039:[DB06728 DB08878] DB06728|Aniline KLK1;ALB;CYP2E1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 32040:[DB06728 DB14146] DB06728|Aniline KLK1;ALB;CYP2E1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 32041:[DB06728 DB14029] DB06728|Aniline KLK1;ALB;CYP2E1 DB14029|Furafylline CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 32042:[DB06728 DB00808] DB06728|Aniline KLK1;ALB;CYP2E1 DB00808|Indapamide SLC12A3;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 32043:[DB06728 DB09107] DB06728|Aniline KLK1;ALB;CYP2E1 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways 32044:[DB06728 DB03005] DB06728|Aniline KLK1;ALB;CYP2E1 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways 32045:[DB06728 DB00159] DB06728|Aniline KLK1;ALB;CYP2E1 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes ALB common pathways GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006641| triglyceride metabolic process ACSL4;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB;FADS1 GO:0098869| ALB;PTGS2;PTGS1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process PTGS2;PPARD;ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;PTGS2;PTGS1;FADS1 GO:0042493| response to drug PPARG;SLC8A1;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen TRPV1;CYP2E1;PTGS2 32046:[DB06728 DB08442] DB06728|Aniline KLK1;ALB;CYP2E1 DB08442|4-{[(2R)-2-(2-methylphenyl)pyrrolidin-1-yl]carbonyl}benzene-1,3-diol HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 32047:[DB06728 DB04903] DB06728|Aniline KLK1;ALB;CYP2E1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways 32048:[DB06728 DB04273] DB06728|Aniline KLK1;ALB;CYP2E1 DB04273|8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine PNMT common genes common pathways 32049:[DB06728 DB02831] DB06728|Aniline KLK1;ALB;CYP2E1 DB02831|Dihydrogenphosphate DCXR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DCXR 32050:[DB06728 DB00649] DB06728|Aniline KLK1;ALB;CYP2E1 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0098869| ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB 32051:[DB06728 DB07495] DB06728|Aniline KLK1;ALB;CYP2E1 DB07495|5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 32052:[DB06728 DB13200] DB06728|Aniline KLK1;ALB;CYP2E1 DB13200|Lipegfilgrastim CSF3R common genes common pathways 32053:[DB06728 DB07406] DB06728|Aniline KLK1;ALB;CYP2E1 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways 32054:[DB06728 DB00985] DB06728|Aniline KLK1;ALB;CYP2E1 DB00985|Dimenhydrinate HRH1 common genes common pathways 32055:[DB06728 DB01643] DB06728|Aniline KLK1;ALB;CYP2E1 DB01643|Thymidine monophosphate tmk;DTYMK;dnaQ;TYMS;thyA;topA common genes common pathways GO:0042493| response to drug TYMS;CYP2E1 GO:0045471| response to ethanol CYP2E1;TYMS 32056:[DB06728 DB00727] DB06728|Aniline KLK1;ALB;CYP2E1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ALDH2 32057:[DB06728 DB00785] DB06728|Aniline KLK1;ALB;CYP2E1 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways 32058:[DB06728 DB11952] DB06728|Aniline KLK1;ALB;CYP2E1 DB11952|Duvelisib PIK3CG;PIK3CD;CYP3A4;ABCB1;ABCG2 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32059:[DB06728 DB13014] DB06728|Aniline KLK1;ALB;CYP2E1 DB13014|Hypericin GSTA1;GSTP1;ALB common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| GSTP1;GSTA1;ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB;GSTP1 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0045471| response to ethanol CYP2E1;GSTP1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 32060:[DB06728 DB08061] DB06728|Aniline KLK1;ALB;CYP2E1 DB08061|4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process ALB;F2 32061:[DB06728 DB05197] DB06728|Aniline KLK1;ALB;CYP2E1 DB05197|Sofalcone CBR1 common genes common pathways GO:0017144| drug metabolic process CBR1;CYP2E1 GO:0055114| oxidation-reduction process CBR1;CYP2E1 32062:[DB06728 DB03092] DB06728|Aniline KLK1;ALB;CYP2E1 DB03092|5-Hydroxymethyl-Chonduritol AMY1A;AMY2A;AMY2B;AMY2A common genes common pathways 32063:[DB06728 DB07369] DB06728|Aniline KLK1;ALB;CYP2E1 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways 32064:[DB06728 DB00988] DB06728|Aniline KLK1;ALB;CYP2E1 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0045471| response to ethanol SLC6A3;HTR3A;DRD2;DRD3;MAOB;SOD1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C19 GO:0001895| retina homeostasis ALB;SOD1 GO:0055114| oxidation-reduction process DBH;MAOA;CYP2E1;SOD1;CYP2C19;MAOB GO:0042493| response to drug SOD1;CYP2E1;DRD1;SLC6A4;DRD3;SLC6A2;MAOB;COMT;SLC6A3;DRD2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0043066| negative regulation of apoptotic process ALB;SOD1 GO:0002576| platelet degranulation ALB;SOD1 GO:0008202| steroid metabolic process CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1 32065:[DB06728 DB00450] DB06728|Aniline KLK1;ALB;CYP2E1 DB00450|Droperidol DRD2;ADRA1A common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug DRD2;ADRA1A;CYP2E1 32066:[DB06728 DB12742] DB06728|Aniline KLK1;ALB;CYP2E1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0043069| negative regulation of programmed cell death KIT;ALB GO:0010243| response to organic nitrogen FLT3;CYP2E1 GO:0042493| response to drug CYP2E1;RET;RAD51 32067:[DB06728 DB00317] DB06728|Aniline KLK1;ALB;CYP2E1 DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0042493| response to drug CYP2E1;ABCB1;ABCG2;CYP1A1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP1A1;CYP2C19;CYP2D6;CYP3A5;CYP2E1;CYP3A4 GO:0002576| platelet degranulation ORM1;ALB GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2C9;CYP2C19;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A5;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A1;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 32068:[DB06728 DB07920] DB06728|Aniline KLK1;ALB;CYP2E1 DB07920|N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide MMP12 common genes common pathways GO:0006508| proteolysis MMP12;KLK1 32069:[DB06728 DB00737] DB06728|Aniline KLK1;ALB;CYP2E1 DB00737|Meclizine HRH1;NR1I3 common genes common pathways 32070:[DB06728 DB03809] DB06728|Aniline KLK1;ALB;CYP2E1 DB03809|9-Butyl-8-(3-Methoxybenzyl)-9h-Purin-6-Amine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 32071:[DB06728 DB03828] DB06728|Aniline KLK1;ALB;CYP2E1 DB03828|RU78299 SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process ALB;SRC 32072:[DB06728 DB00433] DB06728|Aniline KLK1;ALB;CYP2E1 DB00433|Prochlorperazine DRD2;CYP2D6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;DRD2 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0045471| response to ethanol DRD2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 32073:[DB06728 DB02296] DB06728|Aniline KLK1;ALB;CYP2E1 DB02296|Isoamyl alcohol REN common genes common pathways GO:0006508| proteolysis REN;KLK1 GO:0042493| response to drug REN;CYP2E1 32074:[DB06728 DB04098] DB06728|Aniline KLK1;ALB;CYP2E1 DB04098|Balanol PRKACA common genes common pathways 32075:[DB06728 DB01184] DB06728|Aniline KLK1;ALB;CYP2E1 DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2D6;CYP2B6;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 GO:0045471| response to ethanol CYP2E1;DRD2;DRD3 GO:0042493| response to drug CYP2E1;CYP1A2;DRD2;ABCB1;DRD3 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP1A2;CYP2B6;CYP2D6;CYP2C8;CYP3A5 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6;CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2B6;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2B6;CYP3A5;CYP2C8;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4 32076:[DB06728 DB02818] DB06728|Aniline KLK1;ALB;CYP2E1 DB02818|Iodo-Willardiine GRIA2 common genes common pathways 32077:[DB06728 DB02240] DB06728|Aniline KLK1;ALB;CYP2E1 DB02240|Quinacrine mustard TPR common genes common pathways 32078:[DB06728 DB03015] DB06728|Aniline KLK1;ALB;CYP2E1 DB03015|6-Hydroxy-1,6-Dihydro Purine Nucleoside ADA common genes common pathways GO:0042493| response to drug CYP2E1;ADA GO:0043066| negative regulation of apoptotic process ADA;ALB 32079:[DB06728 DB01877] DB06728|Aniline KLK1;ALB;CYP2E1 DB01877|N-Hydroxy 1n(4-Methoxyphenyl)Sulfonyl-4-(Z,E-N-Methoxyimino)Pyrrolidine-2r-Carboxamide MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 32080:[DB06728 DB08240] DB06728|Aniline KLK1;ALB;CYP2E1 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways GO:0002576| platelet degranulation ALDOA;ALB 32081:[DB06728 DB11915] DB06728|Aniline KLK1;ALB;CYP2E1 DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 32082:[DB06728 DB08028] DB06728|Aniline KLK1;ALB;CYP2E1 DB08028|BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE MMP8 common genes common pathways GO:0006508| proteolysis MMP8;KLK1 32083:[DB06728 DB08697] DB06728|Aniline KLK1;ALB;CYP2E1 DB08697|4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 32084:[DB06728 DB06043] DB06728|Aniline KLK1;ALB;CYP2E1 DB06043|Olaratumab PDGFRA common genes common pathways 32085:[DB06728 DB08513] DB06728|Aniline KLK1;ALB;CYP2E1 DB08513|[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID MAPK1;INSR;IRS1 common genes common pathways 32086:[DB06728 DB01579] DB06728|Aniline KLK1;ALB;CYP2E1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0042493| response to drug SLC6A2;ADRA1A;CYP2E1 32087:[DB06728 DB03848] DB06728|Aniline KLK1;ALB;CYP2E1 DB03848|Benzenesulfinic acid NR1H2 common genes common pathways 32088:[DB06728 DB05964] DB06728|Aniline KLK1;ALB;CYP2E1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0042493| response to drug SLC6A4;CYP2E1;DRD2;SLC6A2 GO:0045471| response to ethanol CYP2E1;DRD2 32089:[DB06728 DB01262] DB06728|Aniline KLK1;ALB;CYP2E1 DB01262|Decitabine DNMT1;DCK common genes common pathways 32090:[DB06728 DB05129] DB06728|Aniline KLK1;ALB;CYP2E1 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 32091:[DB06728 DB07359] DB06728|Aniline KLK1;ALB;CYP2E1 DB07359|3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide GCK common genes common pathways 32092:[DB06728 DB06663] DB06728|Aniline KLK1;ALB;CYP2E1 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32093:[DB06728 DB07753] DB06728|Aniline KLK1;ALB;CYP2E1 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 32094:[DB06728 DB00082] DB06728|Aniline KLK1;ALB;CYP2E1 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C18;CYP2E1;CYP3A4;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0009267| cellular response to starvation GLUL;ALB GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP4A11;CYP2E1;CYP2C18 GO:0042493| response to drug BCHE;CYP2E1 GO:0055114| oxidation-reduction process CYP27A1;CYP2C19;CYP4A11;CYP2E1;CYP3A4;CYP2C18 32095:[DB06728 DB07875] DB06728|Aniline KLK1;ALB;CYP2E1 DB07875|5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 32096:[DB06728 DB01034] DB06728|Aniline KLK1;ALB;CYP2E1 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;FASN 32097:[DB06728 DB07555] DB06728|Aniline KLK1;ALB;CYP2E1 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways 32098:[DB06728 DB07011] DB06728|Aniline KLK1;ALB;CYP2E1 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;CYP2E1 32099:[DB06728 DB04600] DB06728|Aniline KLK1;ALB;CYP2E1 DB04600|4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE CA2 common genes common pathways 32100:[DB06728 DB08773] DB06728|Aniline KLK1;ALB;CYP2E1 DB08773|RALOXIFENE CORE ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;NCOA2 32101:[DB06728 DB07491] DB06728|Aniline KLK1;ALB;CYP2E1 DB07491|5-amino-2,4,6-tribromobenzene-1,3-dicarboxylic acid PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32102:[DB06728 DB03867] DB06728|Aniline KLK1;ALB;CYP2E1 DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;GSR GO:0098869| GSR;ALB 32103:[DB06728 DB08422] DB06728|Aniline KLK1;ALB;CYP2E1 DB08422|[PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 32104:[DB06728 DB03568] DB06728|Aniline KLK1;ALB;CYP2E1 DB03568|Butyric Acid BCHE;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 32105:[DB06728 DB01861] DB06728|Aniline KLK1;ALB;CYP2E1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 32106:[DB06728 DB09137] DB06728|Aniline KLK1;ALB;CYP2E1 DB09137|Technetium Tc-99m mebrofenin SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B3;SLCO1B1 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB 32107:[DB06728 DB03046] DB06728|Aniline KLK1;ALB;CYP2E1 DB03046|7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 32108:[DB06728 DB04557] DB06728|Aniline KLK1;ALB;CYP2E1 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport RXRA;ALB;NR1H4 GO:0043252| sodium-independent organic anion transport ALB;SLCO2A1 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;CYP2C9 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;NR1H4 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1;CYP2C9 32109:[DB06728 DB01692] DB06728|Aniline KLK1;ALB;CYP2E1 DB01692|Dithioerythritol prfA;TK1 common genes common pathways 32110:[DB06728 DB09300] DB06728|Aniline KLK1;ALB;CYP2E1 DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways 32111:[DB06728 DB03884] DB06728|Aniline KLK1;ALB;CYP2E1 DB03884|Phenylpyruvic acid HAO1;SLC16A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;HAO1 32112:[DB06728 DB02082] DB06728|Aniline KLK1;ALB;CYP2E1 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways 32113:[DB06728 DB05831] DB06728|Aniline KLK1;ALB;CYP2E1 DB05831|ING-1 EPCAM common genes common pathways 32114:[DB06728 DB06995] DB06728|Aniline KLK1;ALB;CYP2E1 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways 32115:[DB06728 DB07929] DB06728|Aniline KLK1;ALB;CYP2E1 DB07929|N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE NR1H3;RXRB common genes common pathways 32116:[DB06728 DB07479] DB06728|Aniline KLK1;ALB;CYP2E1 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways GO:0045471| response to ethanol CYP2E1;POLB 32117:[DB06728 DB00870] DB06728|Aniline KLK1;ALB;CYP2E1 DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;PTGS1;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0098869| PTGS1;PTGS2;ALB GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP2C9 GO:0008202| steroid metabolic process UGT2B7;CYP2E1;UGT1A1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug UGT1A1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;PTGS2;CYP2E1;PTGS1 32118:[DB06728 DB03784] DB06728|Aniline KLK1;ALB;CYP2E1 DB03784|Elaidoylamide PLA2G2A common genes common pathways 32119:[DB06728 DB06199] DB06728|Aniline KLK1;ALB;CYP2E1 DB06199|Atrasentan EDNRA common genes common pathways 32120:[DB06728 DB01741] DB06728|Aniline KLK1;ALB;CYP2E1 DB01741|CRA_17693 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32121:[DB06728 DB08130] DB06728|Aniline KLK1;ALB;CYP2E1 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways 32122:[DB06728 DB00028] DB06728|Aniline KLK1;ALB;CYP2E1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:0043687| post-translational protein modification C3;ALB;C4A GO:0044267| cellular protein metabolic process C4A;ALB;C3 GO:0006508| proteolysis C3;C4B;KLK1;C4A GO:0006898| receptor-mediated endocytosis FCGR2B;FCGR1A;ALB;FCGR1B 32123:[DB06728 DB04622] DB06728|Aniline KLK1;ALB;CYP2E1 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways 32124:[DB06728 DB06196] DB06728|Aniline KLK1;ALB;CYP2E1 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways GO:0006508| proteolysis ANPEP;KLK1 32125:[DB06728 DB14057] DB06728|Aniline KLK1;ALB;CYP2E1 DB14057|Valinomycin ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;ABCB11 32126:[DB06728 DB01246] DB06728|Aniline KLK1;ALB;CYP2E1 DB01246|Alimemazine HRH1;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 32127:[DB06728 DB00366] DB06728|Aniline KLK1;ALB;CYP2E1 DB00366|Doxylamine HRH1;CHRM1;NR1I3;CYP2B common genes common pathways 32128:[DB06728 DB01442] DB06728|Aniline KLK1;ALB;CYP2E1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC6A3;MAOB GO:0042493| response to drug HTR2A;CYP2E1;SLC6A4;SLC6A2;MAOB;SLC6A3 GO:0055114| oxidation-reduction process MAOB;MAOA;CYP2E1 32129:[DB06728 DB06980] DB06728|Aniline KLK1;ALB;CYP2E1 DB06980|(2S)-2-(1H-indol-3-yl)hexanoic acid SKP1 common genes common pathways GO:0043687| post-translational protein modification ALB;SKP1 32130:[DB06728 DB07139] DB06728|Aniline KLK1;ALB;CYP2E1 DB07139|3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 32131:[DB06728 DB07760] DB06728|Aniline KLK1;ALB;CYP2E1 DB07760|3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;ALB 32132:[DB06728 DB06900] DB06728|Aniline KLK1;ALB;CYP2E1 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways GO:0006508| proteolysis PRSS8;KLK1 32133:[DB06728 DB06971] DB06728|Aniline KLK1;ALB;CYP2E1 DB06971|N-{2-[(4'-CYANO-1,1'-BIPHENYL-4-YL)OXY]ETHYL}-N'-HYDROXY-N-METHYLUREA MMP8 common genes common pathways GO:0006508| proteolysis MMP8;KLK1 32134:[DB06728 DB00899] DB06728|Aniline KLK1;ALB;CYP2E1 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 32135:[DB06728 DB00218] DB06728|Aniline KLK1;ALB;CYP2E1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 32136:[DB06728 DB13530] DB06728|Aniline KLK1;ALB;CYP2E1 DB13530|Mepindolol CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 32137:[DB06728 DB08842] DB06728|Aniline KLK1;ALB;CYP2E1 DB08842|Acetylcarnitine SLC22A5 common genes common pathways 32138:[DB06728 DB03708] DB06728|Aniline KLK1;ALB;CYP2E1 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways 32139:[DB06728 DB05199] DB06728|Aniline KLK1;ALB;CYP2E1 DB05199|LX1031 TPH1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;TPH1 32140:[DB06728 DB01103] DB06728|Aniline KLK1;ALB;CYP2E1 DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 32141:[DB06728 DB05882] DB06728|Aniline KLK1;ALB;CYP2E1 DB05882|CHF 4227 ESR1;ESR2 common genes common pathways 32142:[DB06728 DB08249] DB06728|Aniline KLK1;ALB;CYP2E1 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHODH GO:0042493| response to drug DHODH;CYP2E1 32143:[DB06728 DB13165] DB06728|Aniline KLK1;ALB;CYP2E1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways 32144:[DB06728 DB04779] DB06728|Aniline KLK1;ALB;CYP2E1 DB04779|ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 32145:[DB06728 DB03346] DB06728|Aniline KLK1;ALB;CYP2E1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR GO:0008202| steroid metabolic process CYP2E1;SULT1E1 32146:[DB06728 DB00686] DB06728|Aniline KLK1;ALB;CYP2E1 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;FGF4 32147:[DB06728 DB07208] DB06728|Aniline KLK1;ALB;CYP2E1 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 32148:[DB06728 DB09093] DB06728|Aniline KLK1;ALB;CYP2E1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB 32149:[DB06728 DB07744] DB06728|Aniline KLK1;ALB;CYP2E1 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways GO:0006508| proteolysis CASP1;KLK1 32150:[DB06728 DB06203] DB06728|Aniline KLK1;ALB;CYP2E1 DB06203|Alogliptin DPP4;CYP3A4;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006508| proteolysis KLK1;DPP4 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 32151:[DB06728 DB13443] DB06728|Aniline KLK1;ALB;CYP2E1 DB13443|Esatenolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 32152:[DB06728 DB05642] DB06728|Aniline KLK1;ALB;CYP2E1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0045471| response to ethanol HTR3A;CYP2E1 GO:0042493| response to drug SLC6A2;CYP2E1 32153:[DB06728 DB08584] DB06728|Aniline KLK1;ALB;CYP2E1 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways 32154:[DB06728 DB04859] DB06728|Aniline KLK1;ALB;CYP2E1 DB04859|Zanapezil ACHE common genes common pathways 32155:[DB06728 DB12548] DB06728|Aniline KLK1;ALB;CYP2E1 DB12548|Sparsentan AGT;EDNRA common genes common pathways 32156:[DB06728 DB00245] DB06728|Aniline KLK1;ALB;CYP2E1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0042493| response to drug SLC6A3;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6;CYP2C19 GO:0045471| response to ethanol CYP2E1;SLC6A3 32157:[DB06728 DB07269] DB06728|Aniline KLK1;ALB;CYP2E1 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways GO:0006508| proteolysis CPB1;KLK1 32158:[DB06728 DB00792] DB06728|Aniline KLK1;ALB;CYP2E1 DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 32159:[DB06728 DB14070] DB06728|Aniline KLK1;ALB;CYP2E1 DB14070|HM-30181 ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 32160:[DB06728 DB04447] DB06728|Aniline KLK1;ALB;CYP2E1 DB04447|1,4-Dithiothreitol acpS;hisD;aroE;LGALS1;CAMK2A;rpmA;ALDH1A1;TRPM7;moaA;MSRA;AXIN1;PPIB;thyA;TPI1;GSTZ1;HMGCR;prfA common genes common pathways GO:0008202| steroid metabolic process HMGCR;CYP2E1 GO:0098869| ALB;GSTZ1 GO:0044267| cellular protein metabolic process ALB;LGALS1 GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0055114| oxidation-reduction process ALDH1A1;MSRA;HMGCR;CYP2E1 GO:0043687| post-translational protein modification LGALS1;ALB GO:0042493| response to drug LGALS1;CYP2E1 GO:0045471| response to ethanol CYP2E1;HMGCR 32161:[DB06728 DB05736] DB06728|Aniline KLK1;ALB;CYP2E1 DB05736|MIV-701 CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 32162:[DB06728 DB07115] DB06728|Aniline KLK1;ALB;CYP2E1 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 32163:[DB06728 DB03477] DB06728|Aniline KLK1;ALB;CYP2E1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0098869| PTGS2;ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 32164:[DB06728 DB00091] DB06728|Aniline KLK1;ALB;CYP2E1 DB00091|Ciclosporin CAMLG;PPP3R2;PPIA;PPIF;CYP3A7;CYP3A5;CYP3A4;CYP2C19;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCC3;ABCB11;ABCC1;SLCO1A2;SLC10A2;SLC10A1;SLC22A6;ABCC10;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1;ABCC2;ABCG2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;PPIF GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2C19;CYP2E1 GO:0015721| bile acid and bile salt transport ABCC3;SLC10A1;SLC10A2;ALB;SLCO1A2;ABCB11;SLCO1B1;SLCO1B3 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A5 GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;SLCO1A2;ALB;SLC22A6 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP2C9;CYP2E1;CYP3A4;CYP3A7 32165:[DB06728 DB05295] DB06728|Aniline KLK1;ALB;CYP2E1 DB05295|Eldecalcitol VDR common genes common pathways 32166:[DB06728 DB08566] DB06728|Aniline KLK1;ALB;CYP2E1 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways GO:0006508| proteolysis CTRB1;KLK1 32167:[DB06728 DB01665] DB06728|Aniline KLK1;ALB;CYP2E1 DB01665|ZK-800270 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32168:[DB06728 DB11156] DB06728|Aniline KLK1;ALB;CYP2E1 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP4A11 GO:0055114| oxidation-reduction process CYP2E1;CYP4A11 32169:[DB06728 DB08935] DB06728|Aniline KLK1;ALB;CYP2E1 DB08935|Obinutuzumab MS4A1 common genes common pathways 32170:[DB06728 DB03878] DB06728|Aniline KLK1;ALB;CYP2E1 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways 32171:[DB06728 DB05131] DB06728|Aniline KLK1;ALB;CYP2E1 DB05131|TTP889 F9 common genes common pathways GO:0006508| proteolysis F9;KLK1 32172:[DB06728 DB05518] DB06728|Aniline KLK1;ALB;CYP2E1 DB05518|Managlinat dialanetil FBP1 common genes common pathways 32173:[DB06728 DB09257] DB06728|Aniline KLK1;ALB;CYP2E1 DB09257|Gimeracil DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP2E1 32174:[DB06728 DB07328] DB06728|Aniline KLK1;ALB;CYP2E1 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 32175:[DB06728 DB08705] DB06728|Aniline KLK1;ALB;CYP2E1 DB08705|6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 32176:[DB06728 DB03434] DB06728|Aniline KLK1;ALB;CYP2E1 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways 32177:[DB06728 DB00429] DB06728|Aniline KLK1;ALB;CYP2E1 DB00429|Carboprost tromethamine PTGER1 common genes common pathways 32178:[DB06728 DB07899] DB06728|Aniline KLK1;ALB;CYP2E1 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways GO:0006508| proteolysis KLK1;CTRB1 32179:[DB06728 DB03262] DB06728|Aniline KLK1;ALB;CYP2E1 DB03262|Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide] CA2 common genes common pathways 32180:[DB06728 DB09546] DB06728|Aniline KLK1;ALB;CYP2E1 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;CYP2E1 32181:[DB06728 DB08964] DB06728|Aniline KLK1;ALB;CYP2E1 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways 32182:[DB06728 DB00981] DB06728|Aniline KLK1;ALB;CYP2E1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0045471| response to ethanol CYP2E1;CHRNB2 32183:[DB06728 DB04772] DB06728|Aniline KLK1;ALB;CYP2E1 DB04772|1-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 32184:[DB06728 DB05507] DB06728|Aniline KLK1;ALB;CYP2E1 DB05507|VX-765 CASP1;IL1B common genes common pathways GO:0006508| proteolysis KLK1;CASP1 32185:[DB06728 DB08496] DB06728|Aniline KLK1;ALB;CYP2E1 DB08496|(R)-warfarin CYP2C8;CYP2C9;CYP2C18;CYP2C19;CYP1A2;CYP1A1;CYP3A4;ALB common genes ALB common pathways GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C18;CYP2C9;CYP1A1;CYP2C8;CYP2C19 GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug CYP1A1;CYP2E1;CYP1A2 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP2C18;CYP1A1;CYP2C9;CYP2C19;CYP2C8 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP2C8 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C18;CYP2C9;CYP2C8;CYP2C19 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 32186:[DB06728 DB03588] DB06728|Aniline KLK1;ALB;CYP2E1 DB03588|Diphenylacetic Acid CTSB common genes common pathways GO:0006508| proteolysis KLK1;CTSB 32187:[DB06728 DB01133] DB06728|Aniline KLK1;ALB;CYP2E1 DB01133|Tiludronic acid ATP6V1A;PTPN1 common genes common pathways 32188:[DB06728 DB08879] DB06728|Aniline KLK1;ALB;CYP2E1 DB08879|Belimumab TNFSF13B common genes common pathways 32189:[DB06728 DB02103] DB06728|Aniline KLK1;ALB;CYP2E1 DB02103|2-Chlorodideoxyadenosine HSP90B1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90B1;ALB GO:0043687| post-translational protein modification HSP90B1;ALB GO:0043066| negative regulation of apoptotic process HSP90B1;ALB GO:0044267| cellular protein metabolic process HSP90B1;ALB 32190:[DB06728 DB02134] DB06728|Aniline KLK1;ALB;CYP2E1 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 32191:[DB06728 DB07846] DB06728|Aniline KLK1;ALB;CYP2E1 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways 32192:[DB06728 DB06550] DB06728|Aniline KLK1;ALB;CYP2E1 DB06550|Bivatuzumab CD44 common genes common pathways GO:0043066| negative regulation of apoptotic process CD44;ALB 32193:[DB06728 DB08023] DB06728|Aniline KLK1;ALB;CYP2E1 DB08023|N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine MAPK10 common genes common pathways 32194:[DB06728 DB05804] DB06728|Aniline KLK1;ALB;CYP2E1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A7 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP19A1;CYP2E1;CYP3A7;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0015721| bile acid and bile salt transport SLCO1A2;ABCB11;SLCO1B1;SLCO1B3;SLC10A6;SLCO2B1;ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1A2;SLCO1B3;SLC22A8;SLCO1B1 GO:0008202| steroid metabolic process CYP3A7;CYP2E1 GO:0098869| PTGS2;ALB 32195:[DB06728 DB03226] DB06728|Aniline KLK1;ALB;CYP2E1 DB03226|Trifluoroethanol ADH1C;HRAS common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1C 32196:[DB06728 DB00970] DB06728|Aniline KLK1;ALB;CYP2E1 DB00970|Dactinomycin TOP2A;TOP2B;SLC22A5;ABCB1;ABCC6;ABCC1;ABCG2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1;ABCG2;ABCC1;ABCC6 32197:[DB06728 DB04144] DB06728|Aniline KLK1;ALB;CYP2E1 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways GO:0042493| response to drug CYP2E1;MDM2 GO:0043066| negative regulation of apoptotic process ALB;MDM2 32198:[DB06728 DB07430] DB06728|Aniline KLK1;ALB;CYP2E1 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways 32199:[DB06728 DB13074] DB06728|Aniline KLK1;ALB;CYP2E1 DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 32200:[DB06728 DB03639] DB06728|Aniline KLK1;ALB;CYP2E1 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways 32201:[DB06728 DB07563] DB06728|Aniline KLK1;ALB;CYP2E1 DB07563|1-{7-cyclohexyl-6-[4-(4-methylpiperazin-1-yl)benzyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine CTSK common genes common pathways GO:0006508| proteolysis KLK1;CTSK 32202:[DB06728 DB11133] DB06728|Aniline KLK1;ALB;CYP2E1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1;PPARG;SREBF1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;ALOX5 GO:0098869| PTGS2;ALB GO:0009267| cellular response to starvation ALB;SREBF1 GO:0008202| steroid metabolic process CYP2E1;SREBF1 32203:[DB06728 DB02376] DB06728|Aniline KLK1;ALB;CYP2E1 DB02376|D-gluconhydroximo-1,5-lactam LCT common genes common pathways 32204:[DB06728 DB01325] DB06728|Aniline KLK1;ALB;CYP2E1 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways 32205:[DB06728 DB01353] DB06728|Aniline KLK1;ALB;CYP2E1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 32206:[DB06728 DB07845] DB06728|Aniline KLK1;ALB;CYP2E1 DB07845|2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process MAPK8;ALB 32207:[DB06728 DB04537] DB06728|Aniline KLK1;ALB;CYP2E1 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways 32208:[DB06728 DB13934] DB06728|Aniline KLK1;ALB;CYP2E1 DB13934|Ligandrol AR common genes common pathways 32209:[DB06728 DB00230] DB06728|Aniline KLK1;ALB;CYP2E1 DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 32210:[DB06728 DB04985] DB06728|Aniline KLK1;ALB;CYP2E1 DB04985|Tigapotide RPSA common genes common pathways 32211:[DB06728 DB01162] DB06728|Aniline KLK1;ALB;CYP2E1 DB01162|Terazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A;CYP2E1 32212:[DB06728 DB05141] DB06728|Aniline KLK1;ALB;CYP2E1 DB05141|LY2181308 BIRC5 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BIRC5 32213:[DB06728 DB00395] DB06728|Aniline KLK1;ALB;CYP2E1 DB00395|Carisoprodol GABRA1;GABRB2;GABRG2;CYP2C19 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 32214:[DB06728 DB00058] DB06728|Aniline KLK1;ALB;CYP2E1 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways GO:0006508| proteolysis ELANE;KLK1 32215:[DB06728 DB12301] DB06728|Aniline KLK1;ALB;CYP2E1 DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 32216:[DB06728 DB00758] DB06728|Aniline KLK1;ALB;CYP2E1 DB00758|Clopidogrel P2RY12;CYP3A4;CYP2B6;CYP3A5;CYP2C19;CYP2C9;CYP1A2;CYP2C8;CES1;ABCB1;SLC22A1;SLC22A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A5;CYP2B6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2C9;CYP2B6 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A5;CYP2B6;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;CYP1A2;ABCB1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8;CYP2C19;CYP2B6;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CES1;CYP3A5;CYP2C19;CYP2C8;CYP2C9;CYP2B6 32217:[DB06728 DB04398] DB06728|Aniline KLK1;ALB;CYP2E1 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO2A1;SLCO2B1;ALB GO:0015721| bile acid and bile salt transport SLCO2B1;ALB 32218:[DB06728 DB06883] DB06728|Aniline KLK1;ALB;CYP2E1 DB06883|1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 32219:[DB06728 DB00100] DB06728|Aniline KLK1;ALB;CYP2E1 DB00100|Coagulation Factor IX (Recombinant) F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0006508| proteolysis F7;F2;F10;KLK1;F11 GO:0006898| receptor-mediated endocytosis LRP1;ALB GO:0002576| platelet degranulation F8;ALB GO:0055114| oxidation-reduction process CYP2E1;F8 GO:0044267| cellular protein metabolic process ALB;F2 32220:[DB06728 DB05099] DB06728|Aniline KLK1;ALB;CYP2E1 DB05099|Ancrod FGA common genes common pathways GO:0044267| cellular protein metabolic process FGA;ALB GO:0002576| platelet degranulation FGA;ALB GO:0043687| post-translational protein modification ALB;FGA 32221:[DB06728 DB07031] DB06728|Aniline KLK1;ALB;CYP2E1 DB07031|3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid RARG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 32222:[DB06728 DB11359] DB06728|Aniline KLK1;ALB;CYP2E1 DB11359|Guaiacol ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 32223:[DB06728 DB07161] DB06728|Aniline KLK1;ALB;CYP2E1 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways 32224:[DB06728 DB03777] DB06728|Aniline KLK1;ALB;CYP2E1 DB03777|Rbt205 Inhibitor PIM1;PDPK1;PRKCI common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;PRKCI;ALB 32225:[DB06728 DB03677] DB06728|Aniline KLK1;ALB;CYP2E1 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways GO:0006805| xenobiotic metabolic process EPHX2;CYP2E1 GO:0017144| drug metabolic process EPHX2;CYP2E1 GO:0019373| epoxygenase P450 pathway EPHX2;CYP2E1 32226:[DB06728 DB11738] DB06728|Aniline KLK1;ALB;CYP2E1 DB11738|Rilmenidine ADRA2A common genes common pathways 32227:[DB06728 DB08009] DB06728|Aniline KLK1;ALB;CYP2E1 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways 32228:[DB06728 DB03886] DB06728|Aniline KLK1;ALB;CYP2E1 DB03886|Biopterin SPR;PTS;DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;SPR;DHFR 32229:[DB06728 DB02530] DB06728|Aniline KLK1;ALB;CYP2E1 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways 32230:[DB06728 DB05879] DB06728|Aniline KLK1;ALB;CYP2E1 DB05879|AME-527 TNF common genes common pathways 32231:[DB06728 DB00588] DB06728|Aniline KLK1;ALB;CYP2E1 DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A7;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2C8 GO:0042493| response to drug ABCB1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP3A7;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 32232:[DB06728 DB11186] DB06728|Aniline KLK1;ALB;CYP2E1 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1;OPRM1 32233:[DB06728 DB13877] DB06728|Aniline KLK1;ALB;CYP2E1 DB13877|Iniparib PARP1 common genes common pathways 32234:[DB06728 DB04476] DB06728|Aniline KLK1;ALB;CYP2E1 DB04476|Trencam-3,2-Hopo LCN2 common genes common pathways 32235:[DB06728 DB08828] DB06728|Aniline KLK1;ALB;CYP2E1 DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes ALB common pathways GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2C8 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB;SMO GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2C8;CYP2E1 GO:0002576| platelet degranulation ORM1;ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8;CYP2C19 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB 32236:[DB06728 DB08325] DB06728|Aniline KLK1;ALB;CYP2E1 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways 32237:[DB06728 DB07449] DB06728|Aniline KLK1;ALB;CYP2E1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 32238:[DB06728 DB01279] DB06728|Aniline KLK1;ALB;CYP2E1 DB01279|Galsulfase PLIN3 common genes common pathways 32239:[DB06728 DB07005] DB06728|Aniline KLK1;ALB;CYP2E1 DB07005|D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 32240:[DB06728 DB00391] DB06728|Aniline KLK1;ALB;CYP2E1 DB00391|Sulpiride DRD2;DRD3;CA2;CA3;BCHE common genes common pathways GO:0042493| response to drug DRD3;BCHE;DRD2;CYP2E1 GO:0045471| response to ethanol CYP2E1;CA3;DRD3;DRD2 32241:[DB06728 DB00388] DB06728|Aniline KLK1;ALB;CYP2E1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug ADRA1A;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process MAOA;CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 32242:[DB06728 DB07933] DB06728|Aniline KLK1;ALB;CYP2E1 DB07933|Erteberel ESR2;ESR1 common genes common pathways 32243:[DB06728 DB07283] DB06728|Aniline KLK1;ALB;CYP2E1 DB07283|9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid FABP4 common genes common pathways 32244:[DB06728 DB00819] DB06728|Aniline KLK1;ALB;CYP2E1 DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0043066| negative regulation of apoptotic process ALB;AQP1 GO:0042493| response to drug CYP2E1;AQP1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;CA3 32245:[DB06728 DB00284] DB06728|Aniline KLK1;ALB;CYP2E1 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 32246:[DB06728 DB01067] DB06728|Aniline KLK1;ALB;CYP2E1 DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;UGT1A1 GO:0017144| drug metabolic process CYP2C9;UGT1A1;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0042493| response to drug CYP2E1;ABCC8;PPARG;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2E1 32247:[DB06728 DB01401] DB06728|Aniline KLK1;ALB;CYP2E1 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| PTGS2;PTGS1;ALB 32248:[DB06728 DB08739] DB06728|Aniline KLK1;ALB;CYP2E1 DB08739|2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dione PREP common genes common pathways GO:0006508| proteolysis PREP;KLK1 32249:[DB06728 DB09085] DB06728|Aniline KLK1;ALB;CYP2E1 DB09085|Tetracaine RYR1;RYR2 common genes common pathways 32250:[DB06728 DB06560] DB06728|Aniline KLK1;ALB;CYP2E1 DB06560|Pascolizumab IL4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;IL4 32251:[DB06728 DB05889] DB06728|Aniline KLK1;ALB;CYP2E1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 32252:[DB06728 DB05367] DB06728|Aniline KLK1;ALB;CYP2E1 DB05367|Actelion-1 EDNRA common genes common pathways 32253:[DB06728 DB01004] DB06728|Aniline KLK1;ALB;CYP2E1 DB01004|Ganciclovir SLC22A1;SLC22A6;SLC22A8;SLC22A7;SLC47A1;SLC47A2 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLC22A7 32254:[DB06728 DB00719] DB06728|Aniline KLK1;ALB;CYP2E1 DB00719|Azatadine HRH1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32255:[DB06728 DB08499] DB06728|Aniline KLK1;ALB;CYP2E1 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways GO:0043066| negative regulation of apoptotic process CASP3;ALB GO:0042493| response to drug CASP3;CYP2E1 GO:0006508| proteolysis KLK1;CASP3 32256:[DB06728 DB01013] DB06728|Aniline KLK1;ALB;CYP2E1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A1 32257:[DB06728 DB08880] DB06728|Aniline KLK1;ALB;CYP2E1 DB08880|Teriflunomide DHODH;CYP2C8;CYP1A2;ABCG2;SLCO1B1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2;CYP2C8 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP2E1;CYP1A2;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP1A2;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2;DHODH;CYP2C8 GO:0042493| response to drug ABCG2;CYP2E1;CYP1A2;DHODH 32258:[DB06728 DB00427] DB06728|Aniline KLK1;ALB;CYP2E1 DB00427|Triprolidine HRH1 common genes common pathways 32259:[DB06728 DB04868] DB06728|Aniline KLK1;ALB;CYP2E1 DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C9;CYP2B6 GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2B6;CYP2C8 GO:0042493| response to drug UGT1A1;ABCG2;ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP2C8;CYP2D6 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2B6;CYP2C9;UGT1A1 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP2B6;CYP2C9;UGT1A1;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 32260:[DB06728 DB04369] DB06728|Aniline KLK1;ALB;CYP2E1 DB04369|1,3,2-Dioxaborolan-2-Ol PRSS3 common genes common pathways GO:0006508| proteolysis PRSS3;KLK1 32261:[DB06728 DB12020] DB06728|Aniline KLK1;ALB;CYP2E1 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A4;CYP2E1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1 32262:[DB06728 DB07120] DB06728|Aniline KLK1;ALB;CYP2E1 DB07120|N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINE F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis KLK1;F2 32263:[DB06728 DB06235] DB06728|Aniline KLK1;ALB;CYP2E1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;UGT1A9 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2;UGT2B7 GO:0017144| drug metabolic process UGT1A9;CYP2E1;CYP1A2 32264:[DB06728 DB04971] DB06728|Aniline KLK1;ALB;CYP2E1 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 32265:[DB06728 DB14066] DB06728|Aniline KLK1;ALB;CYP2E1 DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 32266:[DB06728 DB06919] DB06728|Aniline KLK1;ALB;CYP2E1 DB06919|D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis F2;KLK1 32267:[DB06728 DB00337] DB06728|Aniline KLK1;ALB;CYP2E1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB;MTOR GO:0008202| steroid metabolic process CYP2E1;CYP3A4 32268:[DB06728 DB01069] DB06728|Aniline KLK1;ALB;CYP2E1 DB01069|Promethazine HRH1;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;HTR2A;CALM1;HRH2;CYP2D6;CYP2B6;CYP2C9;ABCB1 common genes common pathways GO:0002576| platelet degranulation ALB;CALM1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6;CYP2B6;CYP2C9 GO:0042493| response to drug HTR2A;CYP2E1;ABCB1;DRD2;ADRA1A GO:0008202| steroid metabolic process CYP2E1;CYP2B6;CYP2C9;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP2D6;CYP2C9;CYP2B6 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6;CYP2C9;CYP2B6 32269:[DB06728 DB06470] DB06728|Aniline KLK1;ALB;CYP2E1 DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2A6;CYP2C19;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP2C19;CYP2B6 GO:0008202| steroid metabolic process CYP2C19;CYP2B6;CYP3A4;CYP2E1;CYP2A6 GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4;CYP2B6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2B6;CYP2E1;CYP3A4 32270:[DB06728 DB05092] DB06728|Aniline KLK1;ALB;CYP2E1 DB05092|CDP323 ITGA4 common genes common pathways 32271:[DB06728 DB01340] DB06728|Aniline KLK1;ALB;CYP2E1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis KLK1;ACE GO:0042493| response to drug CYP2E1;ABCB1 32272:[DB06728 DB01177] DB06728|Aniline KLK1;ALB;CYP2E1 DB01177|Idarubicin TOP2A;CYP2C9;CYP2D6;ABCC1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6;CYP2C9 GO:0042493| response to drug CYP2E1;ABCC1 32273:[DB06728 DB01042] DB06728|Aniline KLK1;ALB;CYP2E1 DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways 32274:[DB06728 DB05297] DB06728|Aniline KLK1;ALB;CYP2E1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0043066| negative regulation of apoptotic process BCL2;ALB GO:0042493| response to drug CYP2E1;BCL2 32275:[DB06728 DB03738] DB06728|Aniline KLK1;ALB;CYP2E1 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 32276:[DB06728 DB00009] DB06728|Aniline KLK1;ALB;CYP2E1 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0006508| proteolysis KLK1;PLG GO:0044267| cellular protein metabolic process FGA;ALB;PLG GO:0043687| post-translational protein modification FGA;ALB GO:0043066| negative regulation of apoptotic process PLAUR;ALB GO:0002576| platelet degranulation PLG;ALB;FGA;SERPINE1 32277:[DB06728 DB08890] DB06728|Aniline KLK1;ALB;CYP2E1 DB08890|Linaclotide GUCY2C common genes common pathways 32278:[DB06728 DB08436] DB06728|Aniline KLK1;ALB;CYP2E1 DB08436|8-BENZO[1,3]DIOXOL-,5-YLMETHYL-9-BUTYL-9H- HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 32279:[DB06728 DB12364] DB06728|Aniline KLK1;ALB;CYP2E1 DB12364|Betrixaban F10;F2;ABCB1;KCNH2 common genes common pathways GO:0006508| proteolysis KLK1;F2;F10 GO:0042493| response to drug ABCB1;CYP2E1 GO:0044267| cellular protein metabolic process ALB;F2 32280:[DB06728 DB11134] DB06728|Aniline KLK1;ALB;CYP2E1 DB11134|Cupric oxide ALB;CP common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB;CP GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0055114| oxidation-reduction process CP;CYP2E1 GO:0043687| post-translational protein modification ALB;CP GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 32281:[DB06728 DB07285] DB06728|Aniline KLK1;ALB;CYP2E1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MMP9 GO:0006508| proteolysis KLK1;MMP9 32282:[DB06728 DB03390] DB06728|Aniline KLK1;ALB;CYP2E1 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways 32283:[DB06728 DB07206] DB06728|Aniline KLK1;ALB;CYP2E1 DB07206|6-[2-(1H-INDOL-6-YL)ETHYL]PYRIDIN-2-AMINE BACE1 common genes common pathways GO:0044267| cellular protein metabolic process ALB;BACE1 GO:0006508| proteolysis KLK1;BACE1 32284:[DB06728 DB07502] DB06728|Aniline KLK1;ALB;CYP2E1 DB07502|4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 32285:[DB06728 DB07419] DB06728|Aniline KLK1;ALB;CYP2E1 DB07419|S-23 AR common genes common pathways 32286:[DB06728 DB01001] DB06728|Aniline KLK1;ALB;CYP2E1 DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 32287:[DB06728 DB07876] DB06728|Aniline KLK1;ALB;CYP2E1 DB07876|(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE PRKACA;PKIA;ROCK1 common genes common pathways 32288:[DB06728 DB04689] DB06728|Aniline KLK1;ALB;CYP2E1 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 32289:[DB06728 DB01002] DB06728|Aniline KLK1;ALB;CYP2E1 DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4 32290:[DB06728 DB04842] DB06728|Aniline KLK1;ALB;CYP2E1 DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug DRD2;HTR2A;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 32291:[DB06728 DB04577] DB06728|Aniline KLK1;ALB;CYP2E1 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 32292:[DB06728 DB04099] DB06728|Aniline KLK1;ALB;CYP2E1 DB04099|Deamido-Nad+ nadE;NMNAT1;nadD;NMNAT3;nadE;nadE common genes common pathways 32293:[DB06728 DB10770] DB06728|Aniline KLK1;ALB;CYP2E1 DB10770|Foreskin fibroblast (neonatal) IL6;FLT1;IL1R1;TGFBR2;FGF1;IFNG;FGFR2;CSF2RA;PDGFRB;TGFB1;TNF common genes common pathways GO:0045471| response to ethanol CYP2E1;FGFR2 GO:0006898| receptor-mediated endocytosis TGFBR2;ALB GO:0043066| negative regulation of apoptotic process ALB;IL6;PDGFRB GO:0002576| platelet degranulation TGFB1;ALB GO:0043687| post-translational protein modification ALB;IL6 GO:0042493| response to drug CYP2E1;TGFBR2;TGFB1 GO:0044267| cellular protein metabolic process ALB;IL6;CSF2RA 32294:[DB06728 DB07069] DB06728|Aniline KLK1;ALB;CYP2E1 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 32295:[DB06728 DB07728] DB06728|Aniline KLK1;ALB;CYP2E1 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways 32296:[DB06728 DB00509] DB06728|Aniline KLK1;ALB;CYP2E1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0055114| oxidation-reduction process TPO;CYP2E1 GO:0098869| TPO;ALB GO:0043252| sodium-independent organic anion transport SLCO4C1;ALB;SLCO1C1;SLCO4A1;SLCO1B1 GO:0015721| bile acid and bile salt transport ALB;SLCO1C1;SLCO1B1 32297:[DB06728 DB11118] DB06728|Aniline KLK1;ALB;CYP2E1 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways GO:0009267| cellular response to starvation GLUL;ALB GO:0042493| response to drug CYP2E1;CPS1 GO:0006508| proteolysis CPS1;KLK1 32298:[DB06728 DB01392] DB06728|Aniline KLK1;ALB;CYP2E1 DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol HTR1B;DRD2;DRD3;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug DRD3;DRD2;HTR1B;HTR2C;HTR2B;HTR2A;CYP2E1;KCNJ11 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 32299:[DB06728 DB07882] DB06728|Aniline KLK1;ALB;CYP2E1 DB07882|4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID IGKC common genes common pathways GO:0001895| retina homeostasis IGKC;ALB GO:0006898| receptor-mediated endocytosis ALB;IGKC GO:0006508| proteolysis KLK1;IGKC 32300:[DB06728 DB08766] DB06728|Aniline KLK1;ALB;CYP2E1 DB08766|Zofenoprilat LAP3 common genes common pathways GO:0006508| proteolysis LAP3;KLK1 32301:[DB06728 DB01809] DB06728|Aniline KLK1;ALB;CYP2E1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0042493| response to drug RET;CYP2E1 GO:0043066| negative regulation of apoptotic process HCK;ALB 32302:[DB06728 DB00833] DB06728|Aniline KLK1;ALB;CYP2E1 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0043066| negative regulation of apoptotic process MPO;ALB GO:0055114| oxidation-reduction process MPO;CYP2E1 32303:[DB06728 DB00591] DB06728|Aniline KLK1;ALB;CYP2E1 DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ANXA1 GO:0043066| negative regulation of apoptotic process ANXA5;ANXA4;ALB;ANXA1 GO:0002576| platelet degranulation ANXA5;ALB 32304:[DB06728 DB08763] DB06728|Aniline KLK1;ALB;CYP2E1 DB08763|[N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32305:[DB06728 DB02326] DB06728|Aniline KLK1;ALB;CYP2E1 DB02326|1-Hydroxyamine-2-Isobutylmalonic Acid MMP8 common genes common pathways GO:0006508| proteolysis KLK1;MMP8 32306:[DB06728 DB01765] DB06728|Aniline KLK1;ALB;CYP2E1 DB01765|(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid CSNK2A1 common genes common pathways 32307:[DB06728 DB00554] DB06728|Aniline KLK1;ALB;CYP2E1 DB00554|Piroxicam PTGS2;PTGS1;CYP2C9;CYP2C8;ALB;SLC22A6;SLC22A8;SLC22A11;SLCO2B1 common genes ALB common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A11;SLC22A6;SLCO2B1;ALB GO:0017144| drug metabolic process CYP2E1;CYP2C9;CYP2C8 GO:0098869| ALB;PTGS1;PTGS2 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1;CYP2C8;CYP2C9 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1;CYP2C8;CYP2C9 32308:[DB06728 DB01549] DB06728|Aniline KLK1;ALB;CYP2E1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN3A;DRD2 GO:0042493| response to drug CYP2E1;DRD2 32309:[DB06728 DB06788] DB06728|Aniline KLK1;ALB;CYP2E1 DB06788|Histrelin GNRHR common genes common pathways 32310:[DB06728 DB03612] DB06728|Aniline KLK1;ALB;CYP2E1 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0055114| oxidation-reduction process HADH;CYP2E1 GO:0042493| response to drug HADH;CYP2E1 32311:[DB06728 DB01142] DB06728|Aniline KLK1;ALB;CYP2E1 DB01142|Doxepin HRH1;HRH2;SLC6A2;SLC6A4;HTR2A;HTR2B;HTR2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR1A;ADRA2A;ADRA2B;ADRA2C;DRD2;HTR6;HRH4;KCNH2;CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;ORM1;ABCB1 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0042493| response to drug ABCB1;DRD2;ADRA1A;HTR2C;HTR2B;SLC6A2;SLC6A4;CYP1A2;CYP2E1;HTR2A GO:0002576| platelet degranulation ALB;ORM1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C19;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C9;CYP2D6;CYP2C19 32312:[DB06728 DB05271] DB06728|Aniline KLK1;ALB;CYP2E1 DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2;DRD3 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0042493| response to drug DRD3;DRD2;CYP2E1;DRD1 32313:[DB06728 DB08399] DB06728|Aniline KLK1;ALB;CYP2E1 DB08399|PICEATANNOL ATP5B common genes common pathways 32314:[DB06728 DB06693] DB06728|Aniline KLK1;ALB;CYP2E1 DB06693|Mevastatin HMGCR;CES1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HMGCR GO:0055114| oxidation-reduction process CYP2E1;HMGCR GO:0008202| steroid metabolic process HMGCR;CYP2E1 GO:0045471| response to ethanol HMGCR;CYP2E1 GO:0006805| xenobiotic metabolic process CES1;CYP2E1 32315:[DB06728 DB02422] DB06728|Aniline KLK1;ALB;CYP2E1 DB02422|Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside MAN1B1 common genes common pathways 32316:[DB06728 DB07597] DB06728|Aniline KLK1;ALB;CYP2E1 DB07597|CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 32317:[DB06728 DB08287] DB06728|Aniline KLK1;ALB;CYP2E1 DB08287|(1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 32318:[DB06728 DB00904] DB06728|Aniline KLK1;ALB;CYP2E1 DB00904|Ondansetron HTR3A;HTR4;OPRM1;HTR1A;HTR1B;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP2C9;CYP2E1 common genes CYP2E1 common pathways GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0045471| response to ethanol HTR3A;HTR1B;CYP2E1;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0010193| response to ozone CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug HTR1B;CYP1A2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 32319:[DB06728 DB02457] DB06728|Aniline KLK1;ALB;CYP2E1 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;LIPF GO:0055114| oxidation-reduction process CYP2E1;LIPF 32320:[DB06728 DB04057] DB06728|Aniline KLK1;ALB;CYP2E1 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways 32321:[DB06728 DB08831] DB06728|Aniline KLK1;ALB;CYP2E1 DB08831|2-deoxyglucose SLC2A1 common genes common pathways 32322:[DB06728 DB12323] DB06728|Aniline KLK1;ALB;CYP2E1 DB12323|Radotinib ABL1 common genes common pathways 32323:[DB06728 DB01840] DB06728|Aniline KLK1;ALB;CYP2E1 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways 32324:[DB06728 DB02308] DB06728|Aniline KLK1;ALB;CYP2E1 DB02308|4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-Aminium PRSS3 common genes common pathways GO:0006508| proteolysis KLK1;PRSS3 32325:[DB06728 DB02358] DB06728|Aniline KLK1;ALB;CYP2E1 DB02358|LY374571 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MTHFD1 32326:[DB06728 DB12483] DB06728|Aniline KLK1;ALB;CYP2E1 DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP3A4;CYP3A43;CYP3A5 GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A7;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB 32327:[DB06728 DB04864] DB06728|Aniline KLK1;ALB;CYP2E1 DB04864|Huperzine A ACHE common genes common pathways 32328:[DB06728 DB11693] DB06728|Aniline KLK1;ALB;CYP2E1 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 32329:[DB06728 DB06834] DB06728|Aniline KLK1;ALB;CYP2E1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways 32330:[DB06728 DB07715] DB06728|Aniline KLK1;ALB;CYP2E1 DB07715|Emodin CSNK2A1;fabZ;AHR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;AHR 32331:[DB06728 DB08691] DB06728|Aniline KLK1;ALB;CYP2E1 DB08691|ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate CLK1;CLK3 common genes common pathways 32332:[DB06728 DB00161] DB06728|Aniline KLK1;ALB;CYP2E1 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways 32333:[DB06728 DB00553] DB06728|Aniline KLK1;ALB;CYP2E1 DB00553|Methoxsalen CYP1A2;CYP2A6;CYP1A1;CYP2A13 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP2A13 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP1A2;CYP2A6;CYP2E1;CYP2A13 GO:0042493| response to drug CYP1A1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A1;CYP2A6;CYP2A13;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A1;CYP2A6;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP1A2;CYP2E1;CYP2A6 32334:[DB06728 DB06612] DB06728|Aniline KLK1;ALB;CYP2E1 DB06612|Mepolizumab IL5 common genes common pathways 32335:[DB06728 DB05152] DB06728|Aniline KLK1;ALB;CYP2E1 DB05152|NGX267 CHRM1 common genes common pathways 32336:[DB06728 DB11529] DB06728|Aniline KLK1;ALB;CYP2E1 DB11529|Melengestrol CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 32337:[DB06728 DB01940] DB06728|Aniline KLK1;ALB;CYP2E1 DB01940|Balanol Analog 2 PRKACA common genes common pathways 32338:[DB06728 DB01931] DB06728|Aniline KLK1;ALB;CYP2E1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways GO:0045471| response to ethanol CYP2E1;GRIN1 32339:[DB06728 DB03368] DB06728|Aniline KLK1;ALB;CYP2E1 DB03368|5-Methyl-5-(4-Phenoxy-Phenyl)-Pyrimidine-2,4,6-Trione MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 32340:[DB06728 DB04954] DB06728|Aniline KLK1;ALB;CYP2E1 DB04954|Tecadenoson ADORA1 common genes common pathways GO:0043066| negative regulation of apoptotic process ADORA1;ALB 32341:[DB06728 DB02659] DB06728|Aniline KLK1;ALB;CYP2E1 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0043066| negative regulation of apoptotic process NR1H4;FABP1;ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0055114| oxidation-reduction process MT-CO1;MT-CO2;ABCC4;ADH1C;CYP2E1 GO:0042493| response to drug CYP2E1;ABCC4;FECH;ABCC1;ABCC2;ABCB1 GO:0098869| ALB;FABP1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A7;SLC22A8;SLCO1B1;SLCO1B3;SLCO1A2 GO:0015721| bile acid and bile salt transport NR1H4;SLCO1A2;ABCB11;SLCO1B1;SLCO1B3;SLC10A1;SLC10A2;ALB;ABCC3;FABP6 GO:0006805| xenobiotic metabolic process CES1;CYP2E1 GO:0045471| response to ethanol CYP2E1;FECH 32342:[DB06728 DB01189] DB06728|Aniline KLK1;ALB;CYP2E1 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0055114| oxidation-reduction process MT-ND1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;GABRG3;MT-ND1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB 32343:[DB06728 DB05110] DB06728|Aniline KLK1;ALB;CYP2E1 DB05110|VIR201 IFNG common genes common pathways 32344:[DB06728 DB04301] DB06728|Aniline KLK1;ALB;CYP2E1 DB04301|Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone Hydrate PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32345:[DB06728 DB04307] DB06728|Aniline KLK1;ALB;CYP2E1 DB04307|5-Hydroxy-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0045471| response to ethanol CYP2E1;MAOB GO:0055114| oxidation-reduction process MAOB;CYP2E1 GO:0042493| response to drug MAOB;CYP2E1 32346:[DB06728 DB04899] DB06728|Aniline KLK1;ALB;CYP2E1 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways 32347:[DB06728 DB00432] DB06728|Aniline KLK1;ALB;CYP2E1 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0045471| response to ethanol TYMS;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;TYMS GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB 32348:[DB06728 DB05829] DB06728|Aniline KLK1;ALB;CYP2E1 DB05829|Parathyroid hormone PTH1R;PTH2R common genes common pathways 32349:[DB06728 DB06194] DB06728|Aniline KLK1;ALB;CYP2E1 DB06194|Elocalcitol VDR common genes common pathways 32350:[DB06728 DB12116] DB06728|Aniline KLK1;ALB;CYP2E1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;AHR 32351:[DB06728 DB02104] DB06728|Aniline KLK1;ALB;CYP2E1 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHFR 32352:[DB06728 DB05846] DB06728|Aniline KLK1;ALB;CYP2E1 DB05846|Mito-4509 APP common genes common pathways GO:0044267| cellular protein metabolic process ALB;APP GO:0002576| platelet degranulation ALB;APP GO:0043687| post-translational protein modification APP;ALB 32353:[DB06728 DB04129] DB06728|Aniline KLK1;ALB;CYP2E1 DB04129|Willardiine GRIA2 common genes common pathways 32354:[DB06728 DB08802] DB06728|Aniline KLK1;ALB;CYP2E1 DB08802|Isothipendyl HRH1 common genes common pathways 32355:[DB06728 DB02035] DB06728|Aniline KLK1;ALB;CYP2E1 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways GO:0043066| negative regulation of apoptotic process PPT1;ALB GO:0006898| receptor-mediated endocytosis PPT1;ALB 32356:[DB06728 DB00307] DB06728|Aniline KLK1;ALB;CYP2E1 DB00307|Bexarotene RXRA;RXRB;RXRG;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;RXRA GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4;CYP2E1 32357:[DB06728 DB01051] DB06728|Aniline KLK1;ALB;CYP2E1 DB01051|Novobiocin gyrB;topA;SLC22A6;SLC22A8;SLC22A11;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCG2 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;ALB;SLCO2B1 GO:0043252| sodium-independent organic anion transport SLC22A6;SLCO2B1;ALB;SLCO1B3;SLCO1B1;SLC22A8;SLC22A11 32358:[DB06728 DB13919] DB06728|Aniline KLK1;ALB;CYP2E1 DB13919|Candesartan AGTR1;CYP2C8;CYP2C9;UGT1A3;PTGS1;ABCB1;SLCO1B1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;PTGS1;CYP2C9;CYP2C8 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0008202| steroid metabolic process CYP2E1;CYP2C8;CYP2C9 GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process CYP2C8;CYP2C9;UGT1A3;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1;CYP2C9;CYP2C8 32359:[DB06728 DB07986] DB06728|Aniline KLK1;ALB;CYP2E1 DB07986|[4-(4-PHENYL-PIPERIDIN-1-YL)-BENZENESULFONYLAMINO]-ACETIC ACID MMP3 common genes common pathways GO:0006508| proteolysis KLK1;MMP3 32360:[DB06728 DB04891] DB06728|Aniline KLK1;ALB;CYP2E1 DB04891|Becocalcidiol MED1;VDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;MED1 32361:[DB06728 DB00610] DB06728|Aniline KLK1;ALB;CYP2E1 DB00610|Metaraminol ADRA1A common genes common pathways GO:0042493| response to drug ADRA1A;CYP2E1 32362:[DB06728 DB02597] DB06728|Aniline KLK1;ALB;CYP2E1 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways GO:0006508| proteolysis KLK1;MME 32363:[DB06728 DB02309] DB06728|Aniline KLK1;ALB;CYP2E1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 32364:[DB06728 DB13978] DB06728|Aniline KLK1;ALB;CYP2E1 DB13978|Selisistat SIRT1 common genes common pathways GO:0009267| cellular response to starvation SIRT1;ALB GO:0043066| negative regulation of apoptotic process SIRT1;ALB 32365:[DB06728 DB02547] DB06728|Aniline KLK1;ALB;CYP2E1 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 32366:[DB06728 DB02292] DB06728|Aniline KLK1;ALB;CYP2E1 DB02292|Irosustat CA2;STS common genes common pathways GO:0043687| post-translational protein modification STS;ALB GO:0008202| steroid metabolic process STS;CYP2E1 32367:[DB06728 DB03573] DB06728|Aniline KLK1;ALB;CYP2E1 DB03573|WRR-99 CTSF common genes common pathways GO:0006508| proteolysis CTSF;KLK1 32368:[DB06728 DB06429] DB06728|Aniline KLK1;ALB;CYP2E1 DB06429|Talnetant TACR3 common genes common pathways 32369:[DB06728 DB00731] DB06728|Aniline KLK1;ALB;CYP2E1 DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes ALB common pathways GO:0002576| platelet degranulation ABCC4;ORM1;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP3A5;CYP2D6;CYP2E1;CYP3A4;CYP3A7;PTGS1;ABCC4 GO:0042493| response to drug PPARG;ABCC4;ABCC8;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2C9;UGT1A9 GO:0098869| ALB;PTGS1 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1;CYP3A4;CYP3A7;CYP3A5;CYP2D6;CYP2C9;UGT1A9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 32370:[DB06728 DB04932] DB06728|Aniline KLK1;ALB;CYP2E1 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADORA1 GO:0042493| response to drug CYP2E1;ADORA2A GO:0044267| cellular protein metabolic process ADORA2B;ALB;ADORA2A 32371:[DB06728 DB00644] DB06728|Aniline KLK1;ALB;CYP2E1 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways 32372:[DB06728 DB04927] DB06728|Aniline KLK1;ALB;CYP2E1 DB04927|NM100060 SQLE common genes common pathways GO:0055114| oxidation-reduction process SQLE;CYP2E1 32373:[DB06728 DB02834] DB06728|Aniline KLK1;ALB;CYP2E1 DB02834|IDD552 AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 32374:[DB06728 DB00334] DB06728|Aniline KLK1;ALB;CYP2E1 DB00334|Olanzapine HTR2A;DRD2;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR5A;DRD1;DRD5;HRH2;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;ADRB1;ADRB2;ADRB3;CYP1A2;CYP2D6;FMO3;CYP2C19;CYP3A4;UGT1A1;ALB;ORM1;ABCB1 common genes ALB common pathways GO:0045471| response to ethanol HTR3A;DRD2;HTR1B;DRD3;UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;UGT1A1;CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;FMO3 GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ADRB2;ADRB3;ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process FMO3;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug DRD1;GABRG3;CYP1A2;HTR2A;CYP2E1;DRD2;ADRA1A;ABCB1;HTR1B;HTR2C;HTR2B;UGT1A1;DRD3 GO:0002576| platelet degranulation ALB;ORM1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C19 GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C19;CYP2D6;UGT1A1;CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;UGT1A1 GO:0098869| ALB 32375:[DB06728 DB00783] DB06728|Aniline KLK1;ALB;CYP2E1 DB00783|Estradiol ESR1;ESR2;NR1I2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP3A4;CYP1A2;CYP3A5;CYP3A7;UGT1A1;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes ALB common pathways GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;NR1I2;CYP2C9;CYP1B1;CYP2C8;CYP2C19;CYP3A5 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19;UGT1A1;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B1;SLCO1B3;ALB;SLCO2B1;SLCO1C1;NCOA2 GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP1A1;CYP2C9;UGT1A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4;CYP1A2 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO2B1;SLCO1C1;SLCO4A1;SLC22A11;SLCO1B3;SLCO1B1;SLC22A8;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP1A1;CYP2C9;NR1I2;UGT1A1;CYP3A5;CYP2C19;CYP2C8;CYP1B1;CYP2E1;CYP3A4;CYP1A2;CYP3A7 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1A1;CYP2C9;CYP3A5;CYP2C19;CYP2C8;CYP1B1;CYP3A4;CYP2E1;CYP3A7;CYP1A2;HSD17B2 GO:0042493| response to drug CYP1A1;BECN1;UGT1A1;ABCG2;ABCB1;CYP2E1;CYP1A2 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8;CYP2C19;CYP2C9;CYP1A1;CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;BECN1 32376:[DB06728 DB14543] DB06728|Aniline KLK1;ALB;CYP2E1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1;ABCG2;ANXA1;HSD11B2 GO:0055114| oxidation-reduction process HSD3B1;CYP3A5;HSD11B2;CYP2C8;CYP3A7;CYP11B2;CYP11B1;CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process ANXA1;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP11B1;CYP11B2;CYP3A7;CYP2C8;CYP3A5 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;ALB GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2E1;CYP3A4;CYP3A7 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32377:[DB06728 DB01221] DB06728|Aniline KLK1;ALB;CYP2E1 DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1;SLC6A2;BCHE;HTR2B;HTR2C;HTR1B;DRD2 GO:0055114| oxidation-reduction process CYP2C9;NOS1;CYP2B6;CYP2C8;CYP3A4;CYP2E1;PTGS1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8;CYP2C9;CYP2B6 GO:0010193| response to ozone TACR1;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2C8 GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process CYP2C8;CYP2B6;CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0045471| response to ethanol OPRM1;TACR1;CYP2E1;HTR1B;DRD2;HTR3A;OPRK1;GRIN3A GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP2B6;PTGS1;CYP2E1;CYP3A4 32378:[DB06728 DB07641] DB06728|Aniline KLK1;ALB;CYP2E1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MAOA 32379:[DB06728 DB01876] DB06728|Aniline KLK1;ALB;CYP2E1 DB01876|Bis(5-Amidino-2-Benzimidazolyl)Methanone PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32380:[DB06728 DB04235] DB06728|Aniline KLK1;ALB;CYP2E1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0045471| response to ethanol CYP2E1;ABAT GO:0042493| response to drug ABAT;CYP2E1 32381:[DB06728 DB05541] DB06728|Aniline KLK1;ALB;CYP2E1 DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C9;CYP2B6 GO:0042493| response to drug SCN11A;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2B6;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2B6;CYP2C9 32382:[DB06728 DB00389] DB06728|Aniline KLK1;ALB;CYP2E1 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways GO:0098869| TPO;ALB GO:0055114| oxidation-reduction process CYP2E1;CYP19A1;TPO 32383:[DB06728 DB01164] DB06728|Aniline KLK1;ALB;CYP2E1 DB01164|Calcium Chloride S100A13 common genes common pathways 32384:[DB06728 DB06678] DB06728|Aniline KLK1;ALB;CYP2E1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0042493| response to drug HTR2A;CYP2E1;HTR2B;HTR2C GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 32385:[DB06728 DB08703] DB06728|Aniline KLK1;ALB;CYP2E1 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways 32386:[DB06728 DB04391] DB06728|Aniline KLK1;ALB;CYP2E1 DB04391|Aeruginosin 98-B PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32387:[DB06728 DB09283] DB06728|Aniline KLK1;ALB;CYP2E1 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0042493| response to drug PDE3A;CYP2E1 GO:0043066| negative regulation of apoptotic process PDE3A;ALB 32388:[DB06728 DB00740] DB06728|Aniline KLK1;ALB;CYP2E1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2;CYP1A1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A1;CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;CYP1A1;ABCG2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A1;CYP1A2;CYP2E1 32389:[DB06728 DB07303] DB06728|Aniline KLK1;ALB;CYP2E1 DB07303|N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis KLK1;BACE1 32390:[DB06728 DB09317] DB06728|Aniline KLK1;ALB;CYP2E1 DB09317|Synthetic Conjugated Estrogens, A ESR1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 32391:[DB06728 DB06941] DB06728|Aniline KLK1;ALB;CYP2E1 DB06941|(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide S100B common genes common pathways 32392:[DB06728 DB07268] DB06728|Aniline KLK1;ALB;CYP2E1 DB07268|2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process MAPK8;ALB 32393:[DB06728 DB01482] DB06728|Aniline KLK1;ALB;CYP2E1 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 32394:[DB06728 DB01297] DB06728|Aniline KLK1;ALB;CYP2E1 DB01297|Practolol ADRB1;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1 32395:[DB06728 DB11772] DB06728|Aniline KLK1;ALB;CYP2E1 DB11772|Pilaralisib PIK3CA common genes common pathways 32396:[DB06728 DB14067] DB06728|Aniline KLK1;ALB;CYP2E1 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 32397:[DB06728 DB02095] DB06728|Aniline KLK1;ALB;CYP2E1 DB02095|Isatin MAOB;MAOB common genes common pathways GO:0042493| response to drug MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOB;CYP2E1 GO:0045471| response to ethanol CYP2E1;MAOB 32398:[DB06728 DB09568] DB06728|Aniline KLK1;ALB;CYP2E1 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes common pathways GO:0042493| response to drug HADH;CYP2E1;LPL GO:0055114| oxidation-reduction process CYP3A5;CYP4F2;CYP3A43;CYP3A4;HADH;CYP2E1;HSD17B10;CYP3A7 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP4F2 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0017144| drug metabolic process CYP4F2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0006641| triglyceride metabolic process LPL;CYP2E1 32399:[DB06728 DB00297] DB06728|Aniline KLK1;ALB;CYP2E1 DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 32400:[DB06728 DB02249] DB06728|Aniline KLK1;ALB;CYP2E1 DB02249|2-Ethoxyethanol ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;CYP2E1 32401:[DB06728 DB04841] DB06728|Aniline KLK1;ALB;CYP2E1 DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1;CYP2D6 GO:0017144| drug metabolic process CYP1A1;CYP2C9;CYP2D6;CYP1A2;CYP2A6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2D6;CYP3A4;CYP2E1;CYP2A6;CYP1A2 GO:0042493| response to drug CYP1A1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2A6;CYP3A4;CYP2E1;CYP2D6;CYP1A1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2A6;CYP2E1;CYP1A2;CYP1A1;CYP2C9 GO:0002576| platelet degranulation CALM1;ALB 32402:[DB06728 DB05903] DB06728|Aniline KLK1;ALB;CYP2E1 DB05903|KOS-1584 CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 32403:[DB06728 DB00491] DB06728|Aniline KLK1;ALB;CYP2E1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 32404:[DB06728 DB04556] DB06728|Aniline KLK1;ALB;CYP2E1 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways 32405:[DB06728 DB07368] DB06728|Aniline KLK1;ALB;CYP2E1 DB07368|4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32406:[DB06728 DB09008] DB06728|Aniline KLK1;ALB;CYP2E1 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLC22A6 32407:[DB06728 DB06436] DB06728|Aniline KLK1;ALB;CYP2E1 DB06436|Semaxanib KDR;PTGS2 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;KDR;PTGS2 GO:0098869| PTGS2;ALB 32408:[DB06728 DB00853] DB06728|Aniline KLK1;ALB;CYP2E1 DB00853|Temozolomide CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 32409:[DB06728 DB04970] DB06728|Aniline KLK1;ALB;CYP2E1 DB04970|Lesopitron HTR1A common genes common pathways 32410:[DB06728 DB08546] DB06728|Aniline KLK1;ALB;CYP2E1 DB08546|4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 32411:[DB06728 DB01319] DB06728|Aniline KLK1;ALB;CYP2E1 DB01319|Fosamprenavir pol;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32412:[DB06728 DB00335] DB06728|Aniline KLK1;ALB;CYP2E1 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB2;ALB GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 32413:[DB06728 DB06867] DB06728|Aniline KLK1;ALB;CYP2E1 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways 32414:[DB06728 DB07412] DB06728|Aniline KLK1;ALB;CYP2E1 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 32415:[DB06728 DB02710] DB06728|Aniline KLK1;ALB;CYP2E1 DB02710|2,3,-Dihydroxybenzoylserine LCN2 common genes common pathways 32416:[DB06728 DB14068] DB06728|Aniline KLK1;ALB;CYP2E1 DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1 32417:[DB06728 DB01681] DB06728|Aniline KLK1;ALB;CYP2E1 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways 32418:[DB06728 DB08492] DB06728|Aniline KLK1;ALB;CYP2E1 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways GO:0055114| oxidation-reduction process ALOX15;CYP2E1 32419:[DB06728 DB02504] DB06728|Aniline KLK1;ALB;CYP2E1 DB02504|[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid PLA2G2A common genes common pathways 32420:[DB06728 DB01285] DB06728|Aniline KLK1;ALB;CYP2E1 DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CRH;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process HSD3B2;CYP27B1;CYP3A4;CYP2E1;CYP24A1 GO:0042493| response to drug CYP2E1;CRH GO:0045471| response to ethanol CRH;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32421:[DB06728 DB07076] DB06728|Aniline KLK1;ALB;CYP2E1 DB07076|6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 32422:[DB06728 DB08896] DB06728|Aniline KLK1;ALB;CYP2E1 DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0043069| negative regulation of programmed cell death ALB;KIT GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;UGT1A9;CYP2B6;CYP2C9;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1 GO:0045471| response to ethanol FGFR2;CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP2C9;CYP2B6;UGT1A9;UGT1A1;CYP2C8;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2B6;CYP2C9;UGT1A1;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2B6;CYP2E1 GO:0043066| negative regulation of apoptotic process PDGFRB;FLT4;NTRK1;BRAF;TEK;KDR;ALB;RAF1 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;NTRK1;RET;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2B6 32423:[DB06728 DB00015] DB06728|Aniline KLK1;ALB;CYP2E1 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0043687| post-translational protein modification ALB;FGA GO:0002576| platelet degranulation SERPINE1;PLG;ALB;FGA GO:0043066| negative regulation of apoptotic process PLAUR;ALB GO:0044267| cellular protein metabolic process FGA;ALB;PLG GO:0006508| proteolysis KLK1;PLG 32424:[DB06728 DB08651] DB06728|Aniline KLK1;ALB;CYP2E1 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways 32425:[DB06728 DB07271] DB06728|Aniline KLK1;ALB;CYP2E1 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 32426:[DB06728 DB00231] DB06728|Aniline KLK1;ALB;CYP2E1 DB00231|Temazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP3A4;CYP2B6;CYP2C8;CYP2C9 common genes common pathways GO:0042493| response to drug CYP2E1;TSPO;GABRG3 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8;CYP2C19;CYP2B6;CYP2C9 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C8;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;TSPO;CYP2C19;CYP2C8;CYP2C9;CYP2B6 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9 32427:[DB06728 DB09013] DB06728|Aniline KLK1;ALB;CYP2E1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 32428:[DB06728 DB00277] DB06728|Aniline KLK1;ALB;CYP2E1 DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes CYP2E1 common pathways GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP1A1;CYP2D6 GO:0045471| response to ethanol CYP2E1 GO:0006805| xenobiotic metabolic process CYP1B1;CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006508| proteolysis KLK1;CPNE1;HM13 GO:0043252| sodium-independent organic anion transport SLC22A7;ALB GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP1B1;CYP2D6;CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C8;CYP1A1 GO:0044267| cellular protein metabolic process ALB;ADORA2B;ADORA2A GO:0010193| response to ozone CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1B1;CYP1A1;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process PDE3A;ADORA1;ALB;ADA;HDAC2 GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug ADORA2A;CYP1A1;PDE3A;CYP2E1;CYP1A2;HDAC2;ADA GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP1B1;CYP2C8;CYP2D6;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1 32429:[DB06728 DB06856] DB06728|Aniline KLK1;ALB;CYP2E1 DB06856|6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE PLAU common genes common pathways GO:0006508| proteolysis PLAU;KLK1 32430:[DB06728 DB04612] DB06728|Aniline KLK1;ALB;CYP2E1 DB04612|N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process XIAP;ALB 32431:[DB06728 DB03181] DB06728|Aniline KLK1;ALB;CYP2E1 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways 32432:[DB06728 DB09302] DB06728|Aniline KLK1;ALB;CYP2E1 DB09302|Alirocumab PCSK9 common genes common pathways GO:0006508| proteolysis KLK1;PCSK9 GO:0006641| triglyceride metabolic process CYP2E1;PCSK9 GO:0043687| post-translational protein modification PCSK9;ALB GO:0044267| cellular protein metabolic process ALB;PCSK9 GO:0008202| steroid metabolic process PCSK9;CYP2E1 GO:0009267| cellular response to starvation ALB;PCSK9 32433:[DB06728 DB03906] DB06728|Aniline KLK1;ALB;CYP2E1 DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process HMOX1;CYP2E1 32434:[DB06728 DB13044] DB06728|Aniline KLK1;ALB;CYP2E1 DB13044|Gossypol BCL2L1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BCL2L1 32435:[DB06728 DB12789] DB06728|Aniline KLK1;ALB;CYP2E1 DB12789|Dinoprost PTGDR2 common genes common pathways 32436:[DB06728 DB08321] DB06728|Aniline KLK1;ALB;CYP2E1 DB08321|(1S,2S,3R,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol MAN2A1 common genes common pathways 32437:[DB06728 DB01852] DB06728|Aniline KLK1;ALB;CYP2E1 DB01852|Kaempherol UGT3A1 common genes common pathways 32438:[DB06728 DB02235] DB06728|Aniline KLK1;ALB;CYP2E1 DB02235|L-methionine (R)-S-oxide APP common genes common pathways GO:0044267| cellular protein metabolic process ALB;APP GO:0043687| post-translational protein modification APP;ALB GO:0002576| platelet degranulation ALB;APP 32439:[DB06728 DB01244] DB06728|Aniline KLK1;ALB;CYP2E1 DB01244|Bepridil CACNA1A;CACNA1H;CACNA2D2;ATP1A1;KCNQ1;TNNC1;CALM1;PDE1B;PDE1A;KCNH2;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1;ATP1A1 GO:0002576| platelet degranulation ALB;CALM1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 32440:[DB06728 DB05147] DB06728|Aniline KLK1;ALB;CYP2E1 DB05147|CYT997 TUBA1A;TUBA1B;TUBA1C;TUBA4A;TUBA3C;TUBA3E;TUBA4B;TUBB1;TUBB2A;TUBB2B;TUBB4B;TUBB3;TUBB4A;TUBB;TUBB6 common genes common pathways GO:0002576| platelet degranulation ALB;TUBA4A 32441:[DB06728 DB03551] DB06728|Aniline KLK1;ALB;CYP2E1 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways GO:0042493| response to drug PNP;CYP2E1 32442:[DB06728 DB04043] DB06728|Aniline KLK1;ALB;CYP2E1 DB04043|Carboxymycobactin T LCN2 common genes common pathways 32443:[DB06728 DB01175] DB06728|Aniline KLK1;ALB;CYP2E1 DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0042493| response to drug SLC6A2;ADRA1A;SLC6A3;CYP2E1;SLC6A4 GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 32444:[DB06728 DB13940] DB06728|Aniline KLK1;ALB;CYP2E1 DB13940|2,5-Dimethoxy-4-ethylthioamphetamine HTR2A;HTR2C common genes common pathways GO:0042493| response to drug HTR2A;CYP2E1;HTR2C 32445:[DB06728 DB05073] DB06728|Aniline KLK1;ALB;CYP2E1 DB05073|SRT501 SIRT1 common genes common pathways GO:0043066| negative regulation of apoptotic process SIRT1;ALB GO:0009267| cellular response to starvation ALB;SIRT1 32446:[DB06728 DB07950] DB06728|Aniline KLK1;ALB;CYP2E1 DB07950|Indoleacetic acid PLA2G2E;SKP1;CCBL1 common genes common pathways GO:0043687| post-translational protein modification SKP1;ALB 32447:[DB06728 DB05010] DB06728|Aniline KLK1;ALB;CYP2E1 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways 32448:[DB06728 DB00295] DB06728|Aniline KLK1;ALB;CYP2E1 DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C8;CYP2D6 GO:0008202| steroid metabolic process UGT2B15;UGT1A8;UGT1A1;CYP2D6;CYP2C8;CYP3A4;CYP2E1;UGT2B7 GO:0017144| drug metabolic process UGT1A3;CYP2E1;CYP3A4;CYP2C8;CYP2D6;UGT1A1;UGT1A8 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4;CYP2E1 GO:0045471| response to ethanol UGT1A1;OPRK1;CYP2E1;OPRM1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;UGT2B4;UGT2B15;CYP2C8;CYP2D6 32449:[DB06728 DB05374] DB06728|Aniline KLK1;ALB;CYP2E1 DB05374|Rindopepimut EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;ALB 32450:[DB06728 DB01393] DB06728|Aniline KLK1;ALB;CYP2E1 DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP1A1;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;NR1I2;CYP1A1 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0015721| bile acid and bile salt transport RXRA;ALB;SLCO1B1 GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0019373| epoxygenase P450 pathway CYP2C8;CYP1A1;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A1;PPARG GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A1;CYP2C8 GO:0006805| xenobiotic metabolic process CYP2C8;NR1I2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A1 32451:[DB06728 DB00089] DB06728|Aniline KLK1;ALB;CYP2E1 DB00089|Capromab pendetide FOLH1 common genes common pathways GO:0006508| proteolysis FOLH1;KLK1 32452:[DB06728 DB04583] DB06728|Aniline KLK1;ALB;CYP2E1 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;CYP2E1 GO:0042493| response to drug CYP2E1;DHODH 32453:[DB06728 DB04851] DB06728|Aniline KLK1;ALB;CYP2E1 DB04851|Biricodar dicitrate ABCB5;ABCC1;ABCG2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCG2;ABCC1 32454:[DB06728 DB01675] DB06728|Aniline KLK1;ALB;CYP2E1 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways GO:0055114| oxidation-reduction process ACAD8;CYP2E1 32455:[DB06728 DB09326] DB06728|Aniline KLK1;ALB;CYP2E1 DB09326|Ammonia N-13 NAGS;RHCG common genes common pathways 32456:[DB06728 DB00894] DB06728|Aniline KLK1;ALB;CYP2E1 DB00894|Testolactone CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1 32457:[DB06728 DB07457] DB06728|Aniline KLK1;ALB;CYP2E1 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways 32458:[DB06728 DB07970] DB06728|Aniline KLK1;ALB;CYP2E1 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways 32459:[DB06728 DB07844] DB06728|Aniline KLK1;ALB;CYP2E1 DB07844|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 32460:[DB06728 DB07051] DB06728|Aniline KLK1;ALB;CYP2E1 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways 32461:[DB06728 DB08207] DB06728|Aniline KLK1;ALB;CYP2E1 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 32462:[DB06728 DB02924] DB06728|Aniline KLK1;ALB;CYP2E1 DB02924|(4R)-limonene 1α,2α-epoxide LCN9 common genes common pathways 32463:[DB06728 DB00086] DB06728|Aniline KLK1;ALB;CYP2E1 DB00086|Streptokinase PLG;F2R;PLA2G4A common genes common pathways GO:0006508| proteolysis KLK1;PLG GO:0044267| cellular protein metabolic process PLG;ALB GO:0002576| platelet degranulation PLG;ALB 32464:[DB06728 DB13995] DB06728|Aniline KLK1;ALB;CYP2E1 DB13995|Ferric pyrophosphate citrate FTL;FTH1;HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBB;HBA1 GO:0055114| oxidation-reduction process FTH1;CYP2E1 GO:0098869| HBB;HBA1;ALB 32465:[DB06728 DB11572] DB06728|Aniline KLK1;ALB;CYP2E1 DB11572|Thrombin Alfa F11;F8;F5;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0044267| cellular protein metabolic process FGG;F5;FGA;ALB GO:0002576| platelet degranulation ALB;F13A1;FGA;F5;FGG;F8;FGB GO:0055114| oxidation-reduction process F8;CYP2E1 GO:0043687| post-translational protein modification FGG;F5;FGA;ALB GO:0006508| proteolysis F11;KLK1 32466:[DB06728 DB06795] DB06728|Aniline KLK1;ALB;CYP2E1 DB06795|Mafenide CA6 common genes common pathways 32467:[DB06728 DB00447] DB06728|Aniline KLK1;ALB;CYP2E1 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways 32468:[DB06728 DB05854] DB06728|Aniline KLK1;ALB;CYP2E1 DB05854|CLX-0921 PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 32469:[DB06728 DB00492] DB06728|Aniline KLK1;ALB;CYP2E1 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis ACE;KLK1 32470:[DB06728 DB03213] DB06728|Aniline KLK1;ALB;CYP2E1 DB03213|Bis(5-Amidino-2-Benzimidazolyl)Methane Ketone PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32471:[DB06728 DB00986] DB06728|Aniline KLK1;ALB;CYP2E1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways 32472:[DB06728 DB05443] DB06728|Aniline KLK1;ALB;CYP2E1 DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;CYP2E1 32473:[DB06728 DB05098] DB06728|Aniline KLK1;ALB;CYP2E1 DB05098|Leptin LEPR common genes common pathways 32474:[DB06728 DB00563] DB06728|Aniline KLK1;ALB;CYP2E1 DB00563|Methotrexate DHFR;DHFR;AOX1;MTHFR;PGD;FPGS;TYMS;ATIC;GGH;CYP3A4;ALB;ABCC3;ABCC4;ABCC1;SLC22A6;ABCC10;SLC22A8;ABCC2;ABCB1;SLCO1A2;SLC16A1;ABCC11;SLCO1B3;SLC22A11;SLCO1C1;SLCO3A1;ABCG2;SLC22A7;SLC46A1;SLCO1B1;SLCO4C1;SLC19A1;FOLR1 common genes ALB common pathways GO:0002576| platelet degranulation ALB;ABCC4 GO:0043066| negative regulation of apoptotic process ALB GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process AOX1;DHFR;CYP2E1;CYP3A4;PGD;MTHFR;ABCC4 GO:0042493| response to drug CYP2E1;MTHFR;GGH;ABCC4;TYMS;ABCC1;ABCG2;ABCC2;ABCB1 GO:0017144| drug metabolic process AOX1;CYP2E1;CYP3A4 GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO4C1;SLCO1C1;SLC22A6;SLC22A11;SLC22A7;SLCO1B1;SLC22A8;SLCO1B3;SLCO3A1;SLCO1A2 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;SLCO1A2;ABCC3;SLCO1C1;ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;GGH;TYMS GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006508| proteolysis GGH;KLK1 GO:0006898| receptor-mediated endocytosis ALB;FOLR1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 32475:[DB06728 DB00217] DB06728|Aniline KLK1;ALB;CYP2E1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 32476:[DB06728 DB09101] DB06728|Aniline KLK1;ALB;CYP2E1 DB09101|Elvitegravir pol;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 32477:[DB06728 DB09344] DB06728|Aniline KLK1;ALB;CYP2E1 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways 32478:[DB06728 DB12202] DB06728|Aniline KLK1;ALB;CYP2E1 DB12202|Zalutumumab EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 32479:[DB06728 DB00709] DB06728|Aniline KLK1;ALB;CYP2E1 DB00709|Lamivudine pol;DCK;CMPK1;PGK1;NME1;NME2;PCYT1A;PCYT2;NT5C;ALB;ABCC1;SLC22A6;ABCG2;SLC22A1;SLC22A2;SLC22A3;ABCB1;ABCC4;ABCC3;ABCC2 common genes ALB common pathways GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;ABCC3 GO:0002576| platelet degranulation ALB;ABCC4 GO:0043066| negative regulation of apoptotic process NME2;ALB GO:0042493| response to drug ABCC4;NME1;CYP2E1;ABCB1;ABCG2;ABCC2;ABCC1 GO:0055114| oxidation-reduction process CYP2E1;ABCC4 GO:0043687| post-translational protein modification ALB GO:0010243| response to organic nitrogen CYP2E1;ABCC4 32480:[DB06728 DB01090] DB06728|Aniline KLK1;ALB;CYP2E1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 32481:[DB06728 DB00361] DB06728|Aniline KLK1;ALB;CYP2E1 DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 32482:[DB06728 DB12140] DB06728|Aniline KLK1;ALB;CYP2E1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0044267| cellular protein metabolic process IL6;ALB GO:0043687| post-translational protein modification IL6;ALB GO:0043066| negative regulation of apoptotic process IL6;ALB 32483:[DB06728 DB08520] DB06728|Aniline KLK1;ALB;CYP2E1 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways 32484:[DB06728 DB01291] DB06728|Aniline KLK1;ALB;CYP2E1 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB2 32485:[DB06728 DB02054] DB06728|Aniline KLK1;ALB;CYP2E1 DB02054|Gabaculine OAT common genes common pathways 32486:[DB06728 DB01646] DB06728|Aniline KLK1;ALB;CYP2E1 DB01646|N-Acetylmethionine RHO common genes common pathways 32487:[DB06728 DB00183] DB06728|Aniline KLK1;ALB;CYP2E1 DB00183|Pentagastrin CCKBR;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 32488:[DB06728 DB00495] DB06728|Aniline KLK1;ALB;CYP2E1 DB00495|Zidovudine pol;TERT;CYP2A6;CYP2C8;CYP2C9;CYP3A4;TK1;UGT2B7;UGT1A1;ALB;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLC28A1;SLC29A2;ABCB1;ABCC4;ABCC5;ABCG2 common genes ALB common pathways GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C8 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0098869| ALB GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;CYP2E1;CYP3A4;CYP2A6 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP2C8;CYP2A6;CYP2E1;CYP3A4;UGT2B7 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLC22A11;SLC22A7 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB;ABCC4 GO:0043066| negative regulation of apoptotic process TERT;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6;CYP2C9;CYP2C8 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0042493| response to drug UGT1A1;ABCB1;ABCG2;CYP2E1;ABCC4 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4;CYP2E1;CYP2A6;ABCC4 32489:[DB06728 DB09262] DB06728|Aniline KLK1;ALB;CYP2E1 DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes ALB common pathways GO:0002576| platelet degranulation ORM2;ORM1;ALB GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process UGT1A4;CYP3A4;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 32490:[DB06728 DB01088] DB06728|Aniline KLK1;ALB;CYP2E1 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0015721| bile acid and bile salt transport SLCO2B1;ALB GO:0043252| sodium-independent organic anion transport SLCO2A1;SLCO2B1;ALB;SLCO3A1 GO:0006508| proteolysis PLAT;KLK1 32491:[DB06728 DB05294] DB06728|Aniline KLK1;ALB;CYP2E1 DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;FMO1;CYP3A4;FMO3 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1;FMO1 GO:0042493| response to drug RET;CYP2E1;ABCG2;ABCC1 GO:0055114| oxidation-reduction process FMO1;CYP2E1;CYP3A4;FMO3 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process VEGFA;TEK;EGFR;ALB GO:0002576| platelet degranulation ALB;ORM1;VEGFA 32492:[DB06728 DB02884] DB06728|Aniline KLK1;ALB;CYP2E1 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways 32493:[DB06728 DB04845] DB06728|Aniline KLK1;ALB;CYP2E1 DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32494:[DB06728 DB08575] DB06728|Aniline KLK1;ALB;CYP2E1 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways GO:0006508| proteolysis MME;KLK1 32495:[DB06728 DB02852] DB06728|Aniline KLK1;ALB;CYP2E1 DB02852|Domoic Acid GRIK2 common genes common pathways 32496:[DB06728 DB06413] DB06728|Aniline KLK1;ALB;CYP2E1 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0045471| response to ethanol CYP2E1;SLC6A3 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2B6;CYP2C9;CYP2C19;CYP3A5 GO:0008202| steroid metabolic process CYP3A5;CYP2C19;CYP2C9;CYP2B6;CYP2E1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2B6;CYP2C9;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C19;CYP3A5;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;SLC6A3 32497:[DB06728 DB08085] DB06728|Aniline KLK1;ALB;CYP2E1 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways 32498:[DB06728 DB07802] DB06728|Aniline KLK1;ALB;CYP2E1 DB07802|3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE CSNK2A1 common genes common pathways 32499:[DB06728 DB08356] DB06728|Aniline KLK1;ALB;CYP2E1 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways GO:0009267| cellular response to starvation ALB;PDK4 32500:[DB06728 DB00544] DB06728|Aniline KLK1;ALB;CYP2E1 DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0045471| response to ethanol CYP2E1;TYMS GO:0015721| bile acid and bile salt transport ALB;ABCC3 GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP2A6;CYP2E1;CYP1A2 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB;SLC22A7 GO:0008202| steroid metabolic process CYP2E1;CYP2A6;CYP1A2;CYP2C8;CYP2C9 GO:0010243| response to organic nitrogen CYP2E1;ABCC4 GO:0042493| response to drug ABCC4;PPAT;CYP1A2;MTHFR;CYP2E1;ABCG2;TYMS GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process ABCC4;DPYD;CYP2A6;CYP2E1;MTHFR;CYP1A2;CYP2C8;CYP2C9 GO:0002576| platelet degranulation ABCC4;ALB GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2A6;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB 32501:[DB06728 DB02350] DB06728|Aniline KLK1;ALB;CYP2E1 DB02350|N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 32502:[DB06728 DB09149] DB06728|Aniline KLK1;ALB;CYP2E1 DB09149|Florbetapir (18F) APP common genes common pathways GO:0044267| cellular protein metabolic process ALB;APP GO:0002576| platelet degranulation ALB;APP GO:0043687| post-translational protein modification ALB;APP 32503:[DB06728 DB00542] DB06728|Aniline KLK1;ALB;CYP2E1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis ACE;KLK1 GO:0055114| oxidation-reduction process MTHFR;CYP2E1 GO:0042493| response to drug CYP2E1;MTHFR 32504:[DB06728 DB00742] DB06728|Aniline KLK1;ALB;CYP2E1 DB00742|Mannitol ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 32505:[DB06728 DB00879] DB06728|Aniline KLK1;ALB;CYP2E1 DB00879|Emtricitabine pol;DCK;ALB common genes ALB common pathways GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 32506:[DB06728 DB12391] DB06728|Aniline KLK1;ALB;CYP2E1 DB12391|Sagopilone CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 32507:[DB06728 DB13261] DB06728|Aniline KLK1;ALB;CYP2E1 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 32508:[DB06728 DB01790] DB06728|Aniline KLK1;ALB;CYP2E1 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways 32509:[DB06728 DB08565] DB06728|Aniline KLK1;ALB;CYP2E1 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways GO:0006508| proteolysis KLK1;CTRB1 32510:[DB06728 DB03471] DB06728|Aniline KLK1;ALB;CYP2E1 DB03471|6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid PLA2G2A common genes common pathways 32511:[DB06728 DB07749] DB06728|Aniline KLK1;ALB;CYP2E1 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways GO:0006508| proteolysis CTRB1;KLK1 32512:[DB06728 DB03207] DB06728|Aniline KLK1;ALB;CYP2E1 DB03207|2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid MMP8 common genes common pathways GO:0006508| proteolysis KLK1;MMP8 32513:[DB06728 DB02435] DB06728|Aniline KLK1;ALB;CYP2E1 DB02435|Aminomethylcyclohexane murA;PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32514:[DB06728 DB01093] DB06728|Aniline KLK1;ALB;CYP2E1 DB01093|Dimethyl sulfoxide CYP2C19;CYP2D6;CYP3A4;TTR common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0044267| cellular protein metabolic process ALB;TTR GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19 32515:[DB06728 DB09120] DB06728|Aniline KLK1;ALB;CYP2E1 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes CYP2E1 common pathways GO:0045471| response to ethanol CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP1A2;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C9;CYP2E1;CYP1A2 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2;CYP2C9;CYP2C19 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0010243| response to organic nitrogen CYP2E1;TRPV1 GO:0008202| steroid metabolic process CYP2E1;CYP1A2;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2C9;CYP2E1;CYP1A2 GO:0010193| response to ozone CYP2E1 32516:[DB06728 DB06116] DB06728|Aniline KLK1;ALB;CYP2E1 DB06116|Eldelumab CXCL10 common genes common pathways 32517:[DB06728 DB05848] DB06728|Aniline KLK1;ALB;CYP2E1 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways 32518:[DB06728 DB04036] DB06728|Aniline KLK1;ALB;CYP2E1 DB04036|Coenzyme a Persulfide IVD common genes common pathways GO:0055114| oxidation-reduction process IVD;CYP2E1 32519:[DB06728 DB07240] DB06728|Aniline KLK1;ALB;CYP2E1 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 32520:[DB06728 DB07944] DB06728|Aniline KLK1;ALB;CYP2E1 DB07944|N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process ALB;F2 32521:[DB06728 DB00143] DB06728|Aniline KLK1;ALB;CYP2E1 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0006641| triglyceride metabolic process CYP2E1;GPX1 GO:0006508| proteolysis KLK1;GGT1;MMP9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0006805| xenobiotic metabolic process GSTA4;GSTP1;MGST1;MGST2;GGT1;CYP3A4;CYP2E1;GSTO2;MGST3 GO:0015721| bile acid and bile salt transport ALB;ABCC3 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0098869| MGST3;GSTK1;GPX2;GPX1;GSTO2;GSTO1;GPX5;GPX3;GPX8;MGST2;GPX4;LTC4S;GPX6;GSTT1;ALB;GSR;MGST1;GSTZ1;GSTA1;GSTP1;GSTM2;GPX7 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCC4;ABCC1;MGST1;ABCC2 GO:0055114| oxidation-reduction process GPX8;CYP3A4;GPX3;GPX5;GSTO1;CYP2E1;GPX4;GLRX;TXNDC12;GPX2;GSTK1;ABCC4;GSTO2;GPX1;GLRX2;GPX7;AKR1B1;MGST1;GSR;GPX6 GO:0010243| response to organic nitrogen ABCC4;MGST3;MGST2;CYP2E1;MGST1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0043066| negative regulation of apoptotic process ALB;GSTP1;MMP9;AKR1B1;GPX1;GLO1 32522:[DB06728 DB07345] DB06728|Aniline KLK1;ALB;CYP2E1 DB07345|4-(2-aminoethyl)-2-cyclohexylphenol BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process BACE1;ALB 32523:[DB06728 DB03466] DB06728|Aniline KLK1;ALB;CYP2E1 DB03466|BMS184394 RARG common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;RARG 32524:[DB06728 DB04834] DB06728|Aniline KLK1;ALB;CYP2E1 DB04834|Rapacuronium CHRM2 common genes common pathways 32525:[DB06728 DB03176] DB06728|Aniline KLK1;ALB;CYP2E1 DB03176|KB-141 THRB;THRA common genes common pathways 32526:[DB06728 DB08870] DB06728|Aniline KLK1;ALB;CYP2E1 DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 32527:[DB06728 DB03697] DB06728|Aniline KLK1;ALB;CYP2E1 DB03697|4-Sulfonamide-[1-(4-Aminobutane)]Benzamide CA2 common genes common pathways 32528:[DB06728 DB01785] DB06728|Aniline KLK1;ALB;CYP2E1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0008202| steroid metabolic process CYP2E1;IDI1;FDPS 32529:[DB06728 DB14039] DB06728|Aniline KLK1;ALB;CYP2E1 DB14039|Erenumab CALCRL common genes common pathways 32530:[DB06728 DB03683] DB06728|Aniline KLK1;ALB;CYP2E1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways GO:0006508| proteolysis MMP9;KLK1 GO:0043066| negative regulation of apoptotic process ALB;MMP9 32531:[DB06728 DB03393] DB06728|Aniline KLK1;ALB;CYP2E1 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways 32532:[DB06728 DB01025] DB06728|Aniline KLK1;ALB;CYP2E1 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;S100A12 32533:[DB06728 DB03744] DB06728|Aniline KLK1;ALB;CYP2E1 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways 32534:[DB06728 DB08873] DB06728|Aniline KLK1;ALB;CYP2E1 DB08873|Boceprevir CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP3A5 GO:0055114| oxidation-reduction process CYP3A5;CYP3A4;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1 32535:[DB06728 DB02329] DB06728|Aniline KLK1;ALB;CYP2E1 DB02329|Carbenoxolone HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;HSD11B1 32536:[DB06728 DB01613] DB06728|Aniline KLK1;ALB;CYP2E1 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways 32537:[DB06728 DB01413] DB06728|Aniline KLK1;ALB;CYP2E1 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 32538:[DB06728 DB02016] DB06728|Aniline KLK1;ALB;CYP2E1 DB02016|R048-8071 LSS common genes common pathways 32539:[DB06728 DB02211] DB06728|Aniline KLK1;ALB;CYP2E1 DB02211|N-Methyl-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0042493| response to drug MAOB;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;MAOB GO:0045471| response to ethanol CYP2E1;MAOB 32540:[DB06728 DB01878] DB06728|Aniline KLK1;ALB;CYP2E1 DB01878|Benzophenone ESR1;ESR2 common genes common pathways 32541:[DB06728 DB05383] DB06728|Aniline KLK1;ALB;CYP2E1 DB05383|Pimagedine NOS2;AKR1B1;TIMP3;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;AKR1B1;CYP2E1 GO:0002576| platelet degranulation TIMP3;ALB GO:0043066| negative regulation of apoptotic process AKR1B1;ALB 32542:[DB06728 DB03070] DB06728|Aniline KLK1;ALB;CYP2E1 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;IMPDH2 32543:[DB06728 DB09212] DB06728|Aniline KLK1;ALB;CYP2E1 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0098869| PTGS1;PTGS2;ALB 32544:[DB06728 DB06089] DB06728|Aniline KLK1;ALB;CYP2E1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways 32545:[DB06728 DB00012] DB06728|Aniline KLK1;ALB;CYP2E1 DB00012|Darbepoetin alfa EPOR common genes common pathways 32546:[DB06728 DB09119] DB06728|Aniline KLK1;ALB;CYP2E1 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug CYP2E1;UGT1A1 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0045471| response to ethanol UGT1A1;CYP2E1 32547:[DB06728 DB03929] DB06728|Aniline KLK1;ALB;CYP2E1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0045471| response to ethanol GRIN1;CYP2E1 32548:[DB06728 DB00201] DB06728|Aniline KLK1;ALB;CYP2E1 DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes CYP2E1 common pathways GO:0018910| benzene metabolic process CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PDE3A;ADORA1;PRKDC GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8;CYP2C9;CYP1A1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP1B1;CYP3A5;CYP2C8;CYP2D6;CYP1A1;CYP2C9 GO:0042493| response to drug CYP1A2;CYP2E1;PDE3A;ADORA2A;CYP1A1;ABCB1 GO:0010243| response to organic nitrogen CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP3A5;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP2C9;CYP1A1;CYP2E1;CYP3A4;CYP1A2 GO:0044267| cellular protein metabolic process ADORA2A;ALB GO:0010193| response to ozone CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A7;CYP1A2;CYP3A4;CYP2E1;CYP1B1;CYP3A5;CYP2D6;CYP2C8;CYP2C9 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 32549:[DB06728 DB08100] DB06728|Aniline KLK1;ALB;CYP2E1 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 32550:[DB06728 DB04523] DB06728|Aniline KLK1;ALB;CYP2E1 DB04523|Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 32551:[DB06728 DB04673] DB06728|Aniline KLK1;ALB;CYP2E1 DB04673|4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 32552:[DB06728 DB01685] DB06728|Aniline KLK1;ALB;CYP2E1 DB01685|Topiroxostat XDH;CYP2C8;CYP2C9;CYP1A1;CYP3A4;CYP2C19;UGT1A9;ALB;ORM1;ABCG2;SLC22A8;SLC22A6 common genes ALB common pathways GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C9;CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19;CYP2C9 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2C9;CYP1A1;UGT1A9;CYP3A4;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLC22A6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP1A1;CYP2C9 GO:0042493| response to drug CYP1A1;ABCG2;CYP2E1 GO:0055114| oxidation-reduction process XDH;CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP1A1;CYP2C9 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB;ORM1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8;CYP2C9;CYP1A1 GO:0043066| negative regulation of apoptotic process ALB 32553:[DB06728 DB04924] DB06728|Aniline KLK1;ALB;CYP2E1 DB04924|Itopride DRD2;ACHE common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug DRD2;CYP2E1 32554:[DB06728 DB12455] DB06728|Aniline KLK1;ALB;CYP2E1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 32555:[DB06728 DB00774] DB06728|Aniline KLK1;ALB;CYP2E1 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:0042493| response to drug ATP1A1;CYP2E1;CA9 32556:[DB06728 DB04322] DB06728|Aniline KLK1;ALB;CYP2E1 DB04322|LY249543 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MTHFD1 32557:[DB06728 DB04575] DB06728|Aniline KLK1;ALB;CYP2E1 DB04575|Quinestrol ESR1 common genes common pathways 32558:[DB06728 DB12783] DB06728|Aniline KLK1;ALB;CYP2E1 DB12783|Benserazide DDC common genes common pathways 32559:[DB06728 DB05023] DB06728|Aniline KLK1;ALB;CYP2E1 DB05023|ATL1101 IGF1R common genes common pathways GO:0043066| negative regulation of apoptotic process IGF1R;ALB 32560:[DB06728 DB06350] DB06728|Aniline KLK1;ALB;CYP2E1 DB06350|Elinogrel P2RY12 common genes common pathways 32561:[DB06728 DB00402] DB06728|Aniline KLK1;ALB;CYP2E1 DB00402|Eszopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4;PTGS1 GO:0008202| steroid metabolic process TSPO;CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP2C8;CYP2C9;CYP2E1;CYP3A4 GO:0098869| PTGS1;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP2E1;CYP3A4;PTGS1 GO:0042493| response to drug TSPO;CYP2E1;GABRG3 32562:[DB06728 DB08039] DB06728|Aniline KLK1;ALB;CYP2E1 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways GO:0002576| platelet degranulation CALM1;ALB 32563:[DB06728 DB13985] DB06728|Aniline KLK1;ALB;CYP2E1 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways 32564:[DB06728 DB04615] DB06728|Aniline KLK1;ALB;CYP2E1 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways 32565:[DB06728 DB01567] DB06728|Aniline KLK1;ALB;CYP2E1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 32566:[DB06728 DB08323] DB06728|Aniline KLK1;ALB;CYP2E1 DB08323|3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE IGHG2 common genes common pathways GO:0006508| proteolysis IGHG2;KLK1 32567:[DB06728 DB03636] DB06728|Aniline KLK1;ALB;CYP2E1 DB03636|Glycinamid MMP8 common genes common pathways GO:0006508| proteolysis MMP8;KLK1 32568:[DB06728 DB00480] DB06728|Aniline KLK1;ALB;CYP2E1 DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 32569:[DB06728 DB04376] DB06728|Aniline KLK1;ALB;CYP2E1 DB04376|13-Acetylphorbol PRKCD common genes common pathways 32570:[DB06728 DB00771] DB06728|Aniline KLK1;ALB;CYP2E1 DB00771|Clidinium CHRM1 common genes common pathways 32571:[DB06728 DB05468] DB06728|Aniline KLK1;ALB;CYP2E1 DB05468|R411 ITGA4 common genes common pathways 32572:[DB06728 DB00700] DB06728|Aniline KLK1;ALB;CYP2E1 DB00700|Eplerenone NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP11B2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP11B2;CYP3A7;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP11B2;CYP3A7;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 32573:[DB06728 DB07021] DB06728|Aniline KLK1;ALB;CYP2E1 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 32574:[DB06728 DB07226] DB06728|Aniline KLK1;ALB;CYP2E1 DB07226|N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE WEE1 common genes common pathways 32575:[DB06728 DB06367] DB06728|Aniline KLK1;ALB;CYP2E1 DB06367|Relacatib CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 32576:[DB06728 DB07202] DB06728|Aniline KLK1;ALB;CYP2E1 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;CSF1R 32577:[DB06728 DB08791] DB06728|Aniline KLK1;ALB;CYP2E1 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways 32578:[DB06728 DB06891] DB06728|Aniline KLK1;ALB;CYP2E1 DB06891|5-{[(4-AMINO-3-CHLORO-5-FLUOROPHENYL)SULFONYL]AMINO}-1,3,4-THIADIAZOLE-2-SULFONAMIDE CA2 common genes common pathways 32579:[DB06728 DB08398] DB06728|Aniline KLK1;ALB;CYP2E1 DB08398|2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine ESR1;NCOA2 common genes common pathways GO:0015721| bile acid and bile salt transport NCOA2;ALB 32580:[DB06728 DB00107] DB06728|Aniline KLK1;ALB;CYP2E1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0006508| proteolysis KLK1;PREP GO:0042493| response to drug OXTR;CYP2E1 32581:[DB06728 DB00177] DB06728|Aniline KLK1;ALB;CYP2E1 DB00177|Valsartan AGTR1;CYP2C9;ALB;SLCO1B3;SLCO1B1 common genes ALB common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0098869| ALB GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB 32582:[DB06728 DB09214] DB06728|Aniline KLK1;ALB;CYP2E1 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0098869| PTGS1;PTGS2;ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 32583:[DB06728 DB08292] DB06728|Aniline KLK1;ALB;CYP2E1 DB08292|(5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0006805| xenobiotic metabolic process HSP90AB1;CYP2E1 GO:0042493| response to drug CYP2E1;HSP90AB1 GO:0043066| negative regulation of apoptotic process ALB;HSP90AB1 32584:[DB06728 DB00659] DB06728|Aniline KLK1;ALB;CYP2E1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0042493| response to drug CYP2E1;GRIN2A;GABRG3 GO:0045471| response to ethanol GRIN3A;GRIN2A;GRIN1;GRIN2B;CYP2E1 32585:[DB06728 DB01609] DB06728|Aniline KLK1;ALB;CYP2E1 DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C8;UGT1A9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C8 GO:0042493| response to drug CYP2E1;CYP1A2;UGT1A1 GO:0055114| oxidation-reduction process CYP2C8;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP1A2;UGT1A1;CYP2C8 GO:0017144| drug metabolic process UGT1A3;CYP1A2;CYP2E1;CYP3A4;CYP2C8;UGT1A1;UGT1A9 32586:[DB06728 DB05540] DB06728|Aniline KLK1;ALB;CYP2E1 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways 32587:[DB06728 DB07353] DB06728|Aniline KLK1;ALB;CYP2E1 DB07353|4-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOL F2 common genes common pathways GO:0006508| proteolysis F2;KLK1 GO:0044267| cellular protein metabolic process F2;ALB 32588:[DB06728 DB03331] DB06728|Aniline KLK1;ALB;CYP2E1 DB03331|N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process GAPDHS;CYP2E1 32589:[DB06728 DB09043] DB06728|Aniline KLK1;ALB;CYP2E1 DB09043|Albiglutide GLP1R common genes common pathways 32590:[DB06728 DB00239] DB06728|Aniline KLK1;ALB;CYP2E1 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;NR1I2;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C19;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19;NR1I2 GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 32591:[DB06728 DB00666] DB06728|Aniline KLK1;ALB;CYP2E1 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways 32592:[DB06728 DB00412] DB06728|Aniline KLK1;ALB;CYP2E1 DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;PTGS1;CYP2C9;CYP2C8;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006641| triglyceride metabolic process CYP2E1;ACSL4 GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2A6;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0042493| response to drug CYP2E1;CYP1A2;PPARG GO:0055114| oxidation-reduction process PTGS1;CYP1A2;CYP2A6;CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C9 GO:0043687| post-translational protein modification ALB GO:0098869| ALB;PTGS1 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2C8;CYP1A2;CYP3A4;CYP2E1;CYP2A6 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP2C9;CYP2A6;CYP2E1;CYP3A4;CYP1A2 GO:0015721| bile acid and bile salt transport ALB;RXRA;SLCO1B1;ABCB11 GO:0044267| cellular protein metabolic process ALB 32593:[DB06728 DB07697] DB06728|Aniline KLK1;ALB;CYP2E1 DB07697|1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine PKM common genes common pathways 32594:[DB06728 DB03959] DB06728|Aniline KLK1;ALB;CYP2E1 DB03959|N,O6-Disulfo-Glucosamine FGF2;FGF1;HS3ST3A1;HGF;ANXA5 common genes common pathways GO:0006508| proteolysis KLK1;HGF GO:0002576| platelet degranulation ALB;HGF;ANXA5 GO:0043066| negative regulation of apoptotic process ALB;HGF;ANXA5 32595:[DB06728 DB01608] DB06728|Aniline KLK1;ALB;CYP2E1 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0042493| response to drug DRD1;CYP2E1 32596:[DB06728 DB06982] DB06728|Aniline KLK1;ALB;CYP2E1 DB06982|(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid SKP1 common genes common pathways GO:0043687| post-translational protein modification SKP1;ALB 32597:[DB06728 DB04224] DB06728|Aniline KLK1;ALB;CYP2E1 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport RXRA;ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB;FABP1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug FABP3;PPARG;CYP2E1 GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process PPARD;FABP1;ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 32598:[DB06728 DB06719] DB06728|Aniline KLK1;ALB;CYP2E1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP2E1 32599:[DB06728 DB14487] DB06728|Aniline KLK1;ALB;CYP2E1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0001895| retina homeostasis PRDX1;ALB;JCHAIN;KRT1;TF;IGHA1;SOD1 GO:0034375| high-density lipoprotein particle remodeling APOE;APOA4;APOA2;APOA1;ALB GO:0006641| triglyceride metabolic process APOBR;APOE;APOA2;CYP2E1 GO:0006898| receptor-mediated endocytosis APOE;HBA1;HBB;HPR;JCHAIN;APOBR;ALB;APOA1;IGKV1-17;VTN;APOL1;IGLV3-21;CFI;IGHA1 GO:0006508| proteolysis F12;CPE;BRCC3;IGLV3-21;KLKB1;CFI;C3;C1QC;C1S;DCD;KLK1;C4B;C1R;C1QB;PDIA3;IDE;MMP9;CPN1;PDCD6;F2;CPN2;FCN3;CFB;IGKV1-17 GO:0045471| response to ethanol SOD1;MGMT;CYP2E1;S100A8;GSN;TUFM;TP53 GO:0044267| cellular protein metabolic process APLP2;C3;APCS;TF;ITIH2;APOL1;GSN;P4HB;SERPINA1;INS;TTR;SERPIND1;CP;SEMG1;FN1;APOA2;APP;APOE;APOA4;AHSG;APOA1;ALB;IGFALS;KNG1;F2;FGA GO:0008202| steroid metabolic process APOE;APOA1;APOBR;CYP2E1;APOL1 GO:0098869| ALB;APOE;HBA1;HBB;S100A9 GO:0055114| oxidation-reduction process P4HB;CYP2E1;SOD1;CP;CCS;ADH1C;PDIA3;GAPDHS;PRDX1 GO:0043687| post-translational protein modification FGA;KNG1;APOA1;ALB;AHSG;APP;APOA2;APOE;FN1;SERPIND1;CP;SERPINA1;TF;P4HB;ITIH2;APOL1;C3;APLP2 GO:0042493| response to drug TP73;APOA1;APOA2;MDM2;TP53;HDAC4;HDAC1;NME1;MGMT;CYP2E1;SOD1 GO:0010243| response to organic nitrogen TP73;TP53;CYP2E1 GO:0043066| negative regulation of apoptotic process MT3;SOD1;MGMT;ALB;MMP9;HDAC1;TP53;MDM2 GO:0002576| platelet degranulation AHSG;APOA1;ALB;ITIH3;KNG1;FGA;SERPINA3;A1BG;FN1;APP;SERPINA4;ALDOA;CLU;ORM2;A2M;SERPINA1;APLP2;SOD1;ITIH4;TF 32600:[DB06728 DB01119] DB06728|Aniline KLK1;ALB;CYP2E1 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0042493| response to drug ATP1A1;CYP2E1;KCNJ11 GO:0009267| cellular response to starvation ALB;GLUL 32601:[DB06728 DB05490] DB06728|Aniline KLK1;ALB;CYP2E1 DB05490|T131 PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 32602:[DB06728 DB01671] DB06728|Aniline KLK1;ALB;CYP2E1 DB01671|4-(Hydroxymercury)Benzoic Acid CA2 common genes common pathways 32603:[DB06728 DB04908] DB06728|Aniline KLK1;ALB;CYP2E1 DB04908|Flibanserin HTR1A;HTR2A;DRD4;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;HTR2A GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 32604:[DB06728 DB00842] DB06728|Aniline KLK1;ALB;CYP2E1 DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;UGT2B15;UGT1A9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A43 GO:0042493| response to drug CYP2E1;GABRG3 GO:0017144| drug metabolic process UGT1A9;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process UGT2B7;CYP2E1;CYP3A4;UGT2B15 32605:[DB06728 DB04552] DB06728|Aniline KLK1;ALB;CYP2E1 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0098869| ALB;PTGS1;PTGS2 GO:0017144| drug metabolic process UGT1A9;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1;UGT1A9 32606:[DB06728 DB11217] DB06728|Aniline KLK1;ALB;CYP2E1 DB11217|Arbutin TYR;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0055114| oxidation-reduction process TYR;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 32607:[DB06728 DB03967] DB06728|Aniline KLK1;ALB;CYP2E1 DB03967|Dodecyl sulfate LYZ common genes common pathways GO:0001895| retina homeostasis ALB;LYZ GO:0044267| cellular protein metabolic process ALB;LYZ 32608:[DB06728 DB03541] DB06728|Aniline KLK1;ALB;CYP2E1 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;DHRS4L1;NQO2 GO:0042493| response to drug TYMS;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;NQO2 GO:0045471| response to ethanol CYP2E1;TYMS 32609:[DB06728 DB00138] DB06728|Aniline KLK1;ALB;CYP2E1 DB00138|Cystine SLC7A11;CTNS;SLC7A9;SLC3A1;SLC16A10 common genes common pathways 32610:[DB06728 DB05992] DB06728|Aniline KLK1;ALB;CYP2E1 DB05992|Plinabulin TNF common genes common pathways 32611:[DB06728 DB01010] DB06728|Aniline KLK1;ALB;CYP2E1 DB01010|Edrophonium ACHE;BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 32612:[DB06728 DB01063] DB06728|Aniline KLK1;ALB;CYP2E1 DB01063|Acetophenazine DRD2;DRD1;AR common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug DRD1;CYP2E1;DRD2 32613:[DB06728 DB00440] DB06728|Aniline KLK1;ALB;CYP2E1 DB00440|Trimethoprim TYMS;DHFR;CYP3A4;CYP2C8;CYP2C9;ABCB1;SLC22A2 common genes common pathways GO:0045471| response to ethanol CYP2E1;TYMS GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2C8;DHFR;CYP2C9;CYP3A4;CYP2E1 GO:0042493| response to drug TYMS;ABCB1;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 32614:[DB06728 DB06777] DB06728|Aniline KLK1;ALB;CYP2E1 DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process AKR1C2;NR1I2;UGT2B7;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;NR1H4 GO:0043066| negative regulation of apoptotic process ALB;NR1H4 GO:0055114| oxidation-reduction process CYP27A1;AKR1C2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process NR1I2;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32615:[DB06728 DB04310] DB06728|Aniline KLK1;ALB;CYP2E1 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways 32616:[DB06728 DB06333] DB06728|Aniline KLK1;ALB;CYP2E1 DB06333|Trodusquemine PTPN1;SLC6A3;SLC6A2 common genes common pathways GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0042493| response to drug SLC6A2;SLC6A3;CYP2E1 32617:[DB06728 DB08479] DB06728|Aniline KLK1;ALB;CYP2E1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0045471| response to ethanol CYP2E1;TYMS GO:0042493| response to drug CYP2E1;TYMS 32618:[DB06728 DB04630] DB06728|Aniline KLK1;ALB;CYP2E1 DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP17A1;CYP11B2;CYP11B1;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2 GO:0008202| steroid metabolic process CYP17A1;CYP11B1;CYP11B2;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1A2;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32619:[DB06728 DB02757] DB06728|Aniline KLK1;ALB;CYP2E1 DB02757|Pyrazole ADH1C;ESR1;ESR2 common genes common pathways GO:0055114| oxidation-reduction process ADH1C;CYP2E1 32620:[DB06728 DB02108] DB06728|Aniline KLK1;ALB;CYP2E1 DB02108|2-Aminoethanimidic Acid CTSB common genes common pathways GO:0006508| proteolysis CTSB;KLK1 32621:[DB06728 DB00482] DB06728|Aniline KLK1;ALB;CYP2E1 DB00482|Celecoxib PTGS2;PDPK1;CA2;CA3;ABCB5;ABCG2;ABCB1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;ABCC4;ABCB11 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C8;CYP2C9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2D6 GO:0045471| response to ethanol CA3;CYP2E1 GO:0002576| platelet degranulation ALB;ABCC4 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C9;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2;ABCC4 GO:0042493| response to drug ABCC4;PTGS2;CYP2E1;ABCB1;ABCG2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2E1;ABCC4;CYP2C9;CYP2D6;CYP2C8 GO:0098869| ALB;PTGS2 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C8 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C8;CYP2D6 GO:0015721| bile acid and bile salt transport ALB;ABCB11 32622:[DB06728 DB01695] DB06728|Aniline KLK1;ALB;CYP2E1 DB01695|N-Hydroxy-4-Phosphono-Butanamide TPI1 common genes common pathways 32623:[DB06728 DB01525] DB06728|Aniline KLK1;ALB;CYP2E1 DB01525|Ecgonine BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 32624:[DB06728 DB01035] DB06728|Aniline KLK1;ALB;CYP2E1 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug BCHE;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1;SLC22A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 32625:[DB06728 DB11591] DB06728|Aniline KLK1;ALB;CYP2E1 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways GO:0043252| sodium-independent organic anion transport SLCO1A2;SLCO2B1;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO2B1;SLCO1A2 32626:[DB06728 DB01810] DB06728|Aniline KLK1;ALB;CYP2E1 DB01810|[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways GO:0006508| proteolysis CTSF;KLK1 32627:[DB06728 DB05352] DB06728|Aniline KLK1;ALB;CYP2E1 DB05352|Fx-1006A TTR common genes common pathways GO:0044267| cellular protein metabolic process ALB;TTR 32628:[DB06728 DB06775] DB06728|Aniline KLK1;ALB;CYP2E1 DB06775|Carglumic acid CPS1 common genes common pathways GO:0042493| response to drug CYP2E1;CPS1 GO:0006508| proteolysis CPS1;KLK1 32629:[DB06728 DB05969] DB06728|Aniline KLK1;ALB;CYP2E1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0002576| platelet degranulation VEGFA;ALB GO:0043066| negative regulation of apoptotic process ALB;VEGFA 32630:[DB06728 DB00809] DB06728|Aniline KLK1;ALB;CYP2E1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways 32631:[DB06728 DB00648] DB06728|Aniline KLK1;ALB;CYP2E1 DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process FDX1;CYP2E1;CYP3A4;CYP11B1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process FDX1;CYP3A4;CYP2E1;CYP11B1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32632:[DB06728 DB02047] DB06728|Aniline KLK1;ALB;CYP2E1 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process CYP2E1;PTGS1 32633:[DB06728 DB04879] DB06728|Aniline KLK1;ALB;CYP2E1 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB;FLT4 32634:[DB06728 DB02303] DB06728|Aniline KLK1;ALB;CYP2E1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways GO:0055114| oxidation-reduction process DPYD;CYP2E1 32635:[DB06728 DB00004] DB06728|Aniline KLK1;ALB;CYP2E1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0043066| negative regulation of apoptotic process IL2RB;ALB 32636:[DB06728 DB05461] DB06728|Aniline KLK1;ALB;CYP2E1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug HTR2B;CYP2E1 GO:0043066| negative regulation of apoptotic process HTR2B;ALB 32637:[DB06728 DB01238] DB06728|Aniline KLK1;ALB;CYP2E1 DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;CYP2E1;HTR2A;HTR2C;DRD2;ADRA1A;HTR1B;DRD3 GO:0055114| oxidation-reduction process CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2D6;CYP3A5 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A5;CYP3A7;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0045471| response to ethanol HTR3A;DRD2;HTR1B;DRD3;CYP2E1 32638:[DB06728 DB04849] DB06728|Aniline KLK1;ALB;CYP2E1 DB04849|Cediranib KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB 32639:[DB06728 DB02690] DB06728|Aniline KLK1;ALB;CYP2E1 DB02690|NU1025 PARP1 common genes common pathways 32640:[DB06728 DB07312] DB06728|Aniline KLK1;ALB;CYP2E1 DB07312|2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE FBP1 common genes common pathways 32641:[DB06728 DB01705] DB06728|Aniline KLK1;ALB;CYP2E1 DB01705|Bis(5-Amidino-Benzimidazolyl)Methane PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32642:[DB06728 DB02901] DB06728|Aniline KLK1;ALB;CYP2E1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process HSD17B1;CYP2E1;CYP11A1;CYP17A1;CYP19A1 GO:0008202| steroid metabolic process CYP11A1;CYP2E1;CYP17A1 32643:[DB06728 DB06710] DB06728|Aniline KLK1;ALB;CYP2E1 DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes ALB common pathways GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2B6;CYP19A1 GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2B6 GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1A2 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1A2;SLC22A8 GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2B6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2B6 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB 32644:[DB06728 DB07100] DB06728|Aniline KLK1;ALB;CYP2E1 DB07100|4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 32645:[DB06728 DB00163] DB06728|Aniline KLK1;ALB;CYP2E1 DB00163|Vitamin E NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;SEC14L4;SEC14L3;SEC14L2;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1;NQO1;NR1I2 GO:0045471| response to ethanol GSTP1;NQO1;SOD1;CYP2E1 GO:0001895| retina homeostasis SOD1;ALB GO:0043066| negative regulation of apoptotic process GCLC;SOD1;GSTP1;ALB;NQO1 GO:0002576| platelet degranulation SOD1;ALB GO:0042493| response to drug SOD1;CYP2E1 GO:0055114| oxidation-reduction process ALOX5;HMOX1;GSTO1;CYP2E1;SOD1;NQO1 GO:0098869| GSTO1;GSTP1;ALB GO:0008202| steroid metabolic process CYP2E1;NR1I2 32646:[DB06728 DB03910] DB06728|Aniline KLK1;ALB;CYP2E1 DB03910|S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS3 32647:[DB06728 DB04838] DB06728|Aniline KLK1;ALB;CYP2E1 DB04838|Cyclandelate CACNA2D1;CES1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CES1;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 32648:[DB06728 DB06202] DB06728|Aniline KLK1;ALB;CYP2E1 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes common pathways 32649:[DB06728 DB08798] DB06728|Aniline KLK1;ALB;CYP2E1 DB08798|Sulfamoxole CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 32650:[DB06728 DB05905] DB06728|Aniline KLK1;ALB;CYP2E1 DB05905|TD-2749 HTR4 common genes common pathways 32651:[DB06728 DB07477] DB06728|Aniline KLK1;ALB;CYP2E1 DB07477|Felbinac CTSL common genes common pathways GO:0006508| proteolysis KLK1;CTSL 32652:[DB06728 DB07619] DB06728|Aniline KLK1;ALB;CYP2E1 DB07619|N-cyclopropyl-N-(trans-4-pyridin-3-ylcyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide HSD11B1 common genes common pathways GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 GO:0008202| steroid metabolic process HSD11B1;CYP2E1 32653:[DB06728 DB01156] DB06728|Aniline KLK1;ALB;CYP2E1 DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP2C8;CYP2B6;CYP2C9;CYP2A6;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP2C9;CYP2B6;CYP2E1;CYP3A4;CYP2A6 GO:0042493| response to drug SLC6A3;SLC6A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2C8;CYP2D6;CYP2E1;CYP3A4;CYP2A6 GO:0010243| response to organic nitrogen CYP2E1 GO:0002576| platelet degranulation ORM1;ALB GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2B6;CYP2C9;CYP2A6;CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP2E1;CYP3A4 GO:0045471| response to ethanol SLC6A3;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP2C8;CYP2D6 32654:[DB06728 DB00496] DB06728|Aniline KLK1;ALB;CYP2E1 DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 32655:[DB06728 DB04070] DB06728|Aniline KLK1;ALB;CYP2E1 DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 32656:[DB06728 DB00807] DB06728|Aniline KLK1;ALB;CYP2E1 DB00807|Proparacaine SCN10A common genes common pathways 32657:[DB06728 DB07784] DB06728|Aniline KLK1;ALB;CYP2E1 DB07784|[4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID IGKC common genes common pathways GO:0006898| receptor-mediated endocytosis IGKC;ALB GO:0001895| retina homeostasis IGKC;ALB GO:0006508| proteolysis IGKC;KLK1 32658:[DB06728 DB07121] DB06728|Aniline KLK1;ALB;CYP2E1 DB07121|4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0006508| proteolysis ADAM17;KLK1 GO:0042493| response to drug ADAM17;CYP2E1 32659:[DB06728 DB00318] DB06728|Aniline KLK1;ALB;CYP2E1 DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2D6;CYP3A5;UGT2B4 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2D6 GO:0045471| response to ethanol OPRK1;UGT1A1;OPRM1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT2B7;CYP2E1;CYP3A4;CYP3A7;CYP2D6;CYP3A5;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP3A7;CYP3A4;CYP2E1 32660:[DB06728 DB00443] DB06728|Aniline KLK1;ALB;CYP2E1 DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP19A1 GO:0042493| response to drug CYP2E1;ABCB1 32661:[DB06728 DB01972] DB06728|Aniline KLK1;ALB;CYP2E1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0055114| oxidation-reduction process GMPR;CYP2E1 32662:[DB06728 DB01217] DB06728|Aniline KLK1;ALB;CYP2E1 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP19A1;CYP2C9 32663:[DB06728 DB05662] DB06728|Aniline KLK1;ALB;CYP2E1 DB05662|NP-50301 ESR1 common genes common pathways 32664:[DB06728 DB02621] DB06728|Aniline KLK1;ALB;CYP2E1 DB02621|Latrunculin A ACTA1;GSN common genes common pathways GO:0045471| response to ethanol CYP2E1;GSN GO:0044267| cellular protein metabolic process ALB;GSN 32665:[DB06728 DB05511] DB06728|Aniline KLK1;ALB;CYP2E1 DB05511|Piclidenoson ADORA3 common genes common pathways 32666:[DB06728 DB06879] DB06728|Aniline KLK1;ALB;CYP2E1 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 32667:[DB06728 DB07637] DB06728|Aniline KLK1;ALB;CYP2E1 DB07637|Dibromotyrosine EPOR common genes common pathways 32668:[DB06728 DB06791] DB06728|Aniline KLK1;ALB;CYP2E1 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32669:[DB06728 DB03158] DB06728|Aniline KLK1;ALB;CYP2E1 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways 32670:[DB06728 DB05202] DB06728|Aniline KLK1;ALB;CYP2E1 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways GO:0002576| platelet degranulation VWF;ALB 32671:[DB06728 DB01622] DB06728|Aniline KLK1;ALB;CYP2E1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes ALB common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ADRA1A;DRD2;CYP2E1;HTR2A;DRD1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 32672:[DB06728 DB09286] DB06728|Aniline KLK1;ALB;CYP2E1 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0042493| response to drug DRD3;HTR2B;ADRA1A;DRD2;CYP2E1;HTR2A;DRD1 GO:0045471| response to ethanol DRD3;DRD2;CYP2E1 32673:[DB06728 DB01062] DB06728|Aniline KLK1;ALB;CYP2E1 DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C8;CYP2D6;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C8;CYP2D6;CYP2E1;CYP3A4 32674:[DB06728 DB00693] DB06728|Aniline KLK1;ALB;CYP2E1 DB00693|Fluorescein CYP1A1;SLC22A6;ABCB11;ABCC1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A1 GO:0042493| response to drug CYP1A1;ABCC1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP1A1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 32675:[DB06728 DB05188] DB06728|Aniline KLK1;ALB;CYP2E1 DB05188|KD3010 PPARD common genes common pathways GO:0043066| negative regulation of apoptotic process PPARD;ALB 32676:[DB06728 DB05767] DB06728|Aniline KLK1;ALB;CYP2E1 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0043687| post-translational protein modification IL6;ALB GO:0043066| negative regulation of apoptotic process IL6;ALB;NFKB1 GO:0044267| cellular protein metabolic process IL6;ALB 32677:[DB06728 DB06820] DB06728|Aniline KLK1;ALB;CYP2E1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C9;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C9 32678:[DB06728 DB01320] DB06728|Aniline KLK1;ALB;CYP2E1 DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP2C9;CYP2B6 GO:0002576| platelet degranulation ALB GO:0042493| response to drug CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2B6;CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C19;CYP2D6;UGT1A9;CYP2B6;CYP2C9;CYP1A2;UGT1A6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;UGT1A6;CYP2C9;CYP2B6;UGT1A9;CYP2C19;CYP2D6 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB 32679:[DB06728 DB04268] DB06728|Aniline KLK1;ALB;CYP2E1 DB04268|Methylumbelliferyl Chitotriose LYZ common genes common pathways GO:0001895| retina homeostasis ALB;LYZ GO:0044267| cellular protein metabolic process LYZ;ALB 32680:[DB06728 DB05080] DB06728|Aniline KLK1;ALB;CYP2E1 DB05080|OBE101 HRH1;HRH3 common genes common pathways 32681:[DB06728 DB03504] DB06728|Aniline KLK1;ALB;CYP2E1 DB03504|9-Butyl-8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 32682:[DB06728 DB00871] DB06728|Aniline KLK1;ALB;CYP2E1 DB00871|Terbutaline ADRB2;ADRB3;ADRB1;BCHE common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 GO:0042493| response to drug BCHE;CYP2E1 32683:[DB06728 DB00933] DB06728|Aniline KLK1;ALB;CYP2E1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6 GO:0042493| response to drug CYP2E1;HTR2A;DRD2 GO:0008202| steroid metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2E1 32684:[DB06728 DB00500] DB06728|Aniline KLK1;ALB;CYP2E1 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2;MPO GO:0055114| oxidation-reduction process PTGS2;CYP2E1;TDO2;PTGS1;MPO GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0098869| PTGS2;PTGS1;ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 32685:[DB06728 DB00069] DB06728|Aniline KLK1;ALB;CYP2E1 DB00069|Interferon alfacon-1 IFNAR1;IFNAR2 common genes common pathways 32686:[DB06728 DB13869] DB06728|Aniline KLK1;ALB;CYP2E1 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways 32687:[DB06728 DB08143] DB06728|Aniline KLK1;ALB;CYP2E1 DB08143|5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 32688:[DB06728 DB00804] DB06728|Aniline KLK1;ALB;CYP2E1 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A1 GO:0042493| response to drug CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP2E1;CYP1A1 GO:0017144| drug metabolic process CYP2E1;CYP1A1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 32689:[DB06728 DB02820] DB06728|Aniline KLK1;ALB;CYP2E1 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways GO:0055114| oxidation-reduction process HSD17B10;CYP2E1 32690:[DB06728 DB02155] DB06728|Aniline KLK1;ALB;CYP2E1 DB02155|Balanol Analog 8 PRKACA common genes common pathways 32691:[DB06728 DB09498] DB06728|Aniline KLK1;ALB;CYP2E1 DB09498|Strontium chloride Sr-89 ALPPL2;ALPL;SLC8A1;CACNA1I common genes common pathways GO:0042493| response to drug SLC8A1;CYP2E1 32692:[DB06728 DB00223] DB06728|Aniline KLK1;ALB;CYP2E1 DB00223|Diflorasone NR3C1 common genes common pathways 32693:[DB06728 DB02432] DB06728|Aniline KLK1;ALB;CYP2E1 DB02432|RU90395 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug CYP2E1;SRC 32694:[DB06728 DB02481] DB06728|Aniline KLK1;ALB;CYP2E1 DB02481|N-Benzylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1B 32695:[DB06728 DB01388] DB06728|Aniline KLK1;ALB;CYP2E1 DB01388|Mibefradil CACNA1G;CACNA1H;CACNA1C;CACNA1D;CACNA1F;CACNA1I;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP1A1;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP11B2;CYP11B1;CYP2E1;CYP3A4;CYP3A5;CYP2D6;CYP1A1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A7;CYP11B2;CYP11B1;CYP2E1;CYP3A4;CYP1A1;CYP3A5;CYP2D6 GO:0042493| response to drug ABCB1;CYP1A1;CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP3A4;CYP2E1;CYP1A2 32696:[DB06728 DB00106] DB06728|Aniline KLK1;ALB;CYP2E1 DB00106|Abarelix GNRHR common genes common pathways 32697:[DB06728 DB06947] DB06728|Aniline KLK1;ALB;CYP2E1 DB06947|1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide F2 common genes common pathways GO:0044267| cellular protein metabolic process F2;ALB GO:0006508| proteolysis KLK1;F2 32698:[DB06728 DB00014] DB06728|Aniline KLK1;ALB;CYP2E1 DB00014|Goserelin LHCGR;GNRHR common genes common pathways 32699:[DB06728 DB14062] DB06728|Aniline KLK1;ALB;CYP2E1 DB14062|Concanamycin A ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 32700:[DB06728 DB03596] DB06728|Aniline KLK1;ALB;CYP2E1 DB03596|N-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide CA2 common genes common pathways 32701:[DB06728 DB09118] DB06728|Aniline KLK1;ALB;CYP2E1 DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C19;CYP2C9 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1;CYP2C19;CYP2C9 GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;LDHB;CYP2C9;LDHA;CYP2E1;CYP3A4;CYP1A2 GO:0042493| response to drug GABRG3;CYP2E1;CYP1A2;LDHA 32702:[DB06728 DB14514] DB06728|Aniline KLK1;ALB;CYP2E1 DB14514|Magnesium levulinate ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 32703:[DB06728 DB04278] DB06728|Aniline KLK1;ALB;CYP2E1 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0045471| response to ethanol CYP2E1;IL2 32704:[DB06728 DB04787] DB06728|Aniline KLK1;ALB;CYP2E1 DB04787|Tanaproget PGR common genes common pathways 32705:[DB06728 DB07001] DB06728|Aniline KLK1;ALB;CYP2E1 DB07001|(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;CYP2E1 32706:[DB06728 DB01116] DB06728|Aniline KLK1;ALB;CYP2E1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 32707:[DB06728 DB00729] DB06728|Aniline KLK1;ALB;CYP2E1 DB00729|Diphemanil Methylsulfate CHRM3 common genes common pathways 32708:[DB06728 DB08932] DB06728|Aniline KLK1;ALB;CYP2E1 DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2C19;CYP2E1;CYP3A4 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0043066| negative regulation of apoptotic process EDNRB;ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0098869| ALB GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 32709:[DB06728 DB09086] DB06728|Aniline KLK1;ALB;CYP2E1 DB09086|Eugenol ESR1;ESR2;AR;TRPV3 common genes common pathways 32710:[DB06728 DB07675] DB06728|Aniline KLK1;ALB;CYP2E1 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 32711:[DB06728 DB05038] DB06728|Aniline KLK1;ALB;CYP2E1 DB05038|Anatibant BDKRB2 common genes common pathways 32712:[DB06728 DB13975] DB06728|Aniline KLK1;ALB;CYP2E1 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9 32713:[DB06728 DB07250] DB06728|Aniline KLK1;ALB;CYP2E1 DB07250|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5- TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways 32714:[DB06728 DB06213] DB06728|Aniline KLK1;ALB;CYP2E1 DB06213|Regadenoson ADORA2A common genes common pathways GO:0042493| response to drug ADORA2A;CYP2E1 GO:0044267| cellular protein metabolic process ADORA2A;ALB 32715:[DB06728 DB09327] DB06728|Aniline KLK1;ALB;CYP2E1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0045471| response to ethanol CYP2E1;TYMS GO:0017144| drug metabolic process CYP2A6;CYP2E1 GO:0008202| steroid metabolic process CYP2A6;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A7;ALB GO:0042493| response to drug CYP2E1;TYMS GO:0055114| oxidation-reduction process DPYD;CYP2E1;CYP2A6 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2A6 32716:[DB06728 DB00042] DB06728|Aniline KLK1;ALB;CYP2E1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 32717:[DB06728 DB08386] DB06728|Aniline KLK1;ALB;CYP2E1 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 32718:[DB06728 DB00891] DB06728|Aniline KLK1;ALB;CYP2E1 DB00891|Sulfapyridine CYP2C9 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 32719:[DB06728 DB09374] DB06728|Aniline KLK1;ALB;CYP2E1 DB09374|Indocyanine green acid form IDH1;GLS;ABCC2;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0055114| oxidation-reduction process CYP2E1;IDH1 GO:0042493| response to drug CYP2E1;ABCC2 32720:[DB06728 DB00254] DB06728|Aniline KLK1;ALB;CYP2E1 DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0001895| retina homeostasis B2M;ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB;SLC22A8;SLC22A11 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process B2M;ALB GO:0042493| response to drug CYP2E1;B2M GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 32721:[DB06728 DB04655] DB06728|Aniline KLK1;ALB;CYP2E1 DB04655|Metoprine HNMT common genes common pathways 32722:[DB06728 DB08744] DB06728|Aniline KLK1;ALB;CYP2E1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;NQO2 GO:0055114| oxidation-reduction process CYP2E1;NQO2 32723:[DB06728 DB07175] DB06728|Aniline KLK1;ALB;CYP2E1 DB07175|N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide BACE1 common genes common pathways GO:0006508| proteolysis BACE1;KLK1 GO:0044267| cellular protein metabolic process BACE1;ALB 32724:[DB06728 DB04253] DB06728|Aniline KLK1;ALB;CYP2E1 DB04253|Tretazicar NQO2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NQO2 GO:0006805| xenobiotic metabolic process CYP2E1;NQO2 32725:[DB06728 DB06314] DB06728|Aniline KLK1;ALB;CYP2E1 DB06314|SGX-523 MET common genes common pathways 32726:[DB06728 DB06246] DB06728|Aniline KLK1;ALB;CYP2E1 DB06246|Exisulind PDE4D;PDE4C;PDE5A;PDE2A;GSTP1;AKR1B1;AKR1B10 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;GSTP1 GO:0045471| response to ethanol GSTP1;CYP2E1 GO:0098869| ALB;GSTP1 GO:0008202| steroid metabolic process CYP2E1;AKR1B10 GO:0055114| oxidation-reduction process CYP2E1;AKR1B1;AKR1B10 GO:0043066| negative regulation of apoptotic process GSTP1;ALB;AKR1B1 32727:[DB06728 DB11811] DB06728|Aniline KLK1;ALB;CYP2E1 DB11811|Arhalofenate PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 32728:[DB06728 DB05246] DB06728|Aniline KLK1;ALB;CYP2E1 DB05246|Methsuximide CACNA1G;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19 GO:0008202| steroid metabolic process CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP2C19 32729:[DB06728 DB06096] DB06728|Aniline KLK1;ALB;CYP2E1 DB06096|NXN-188 NOS1;HTR1B;HTR1D common genes common pathways GO:0045471| response to ethanol HTR1B;CYP2E1 GO:0042493| response to drug CYP2E1;HTR1B GO:0055114| oxidation-reduction process CYP2E1;NOS1 32730:[DB06728 DB03227] DB06728|Aniline KLK1;ALB;CYP2E1 DB03227|Nicotinamide Mononucleotide NMNAT1;NMNAT3;BST1;ligA common genes common pathways 32731:[DB06728 DB00938] DB06728|Aniline KLK1;ALB;CYP2E1 DB00938|Salmeterol ADRB2;ADRB1;ADRB3;CYP3A4;CYP3A5;CYP3A7;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0006898| receptor-mediated endocytosis ADRB3;ALB;ADRB2 GO:0006805| xenobiotic metabolic process CYP2C8;CYP3A5;CYP3A7;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 32732:[DB06728 DB07461] DB06728|Aniline KLK1;ALB;CYP2E1 DB07461|3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process ALB;F2 32733:[DB06728 DB05259] DB06728|Aniline KLK1;ALB;CYP2E1 DB05259|Glatiramer HLA-DRB1 common genes common pathways 32734:[DB06728 DB13955] DB06728|Aniline KLK1;ALB;CYP2E1 DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport SLCO1A2;SLCO1B3;SLCO1B1;SLCO1C1;NCOA2;ALB;SLCO2B1 GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP1A1;CYP2C9;UGT1A1;CYP3A4;CYP2E1;CYP1A2 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1C1;ALB;SLCO2B1;SLCO1B3;SLCO1B1;SLC22A8;SLCO1A2;SLCO4A1;SLC22A11 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP1A2;NR1I2;CYP1A1;CYP2C9;UGT1A1;CYP2C8;CYP2C19;CYP3A5;CYP1B1 GO:0055114| oxidation-reduction process CYP1B1;CYP2C8;CYP2C19;CYP3A5;CYP2C9;CYP1A1;HSD17B2;CYP3A7;CYP1A2;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug CYP1A1;BECN1;UGT1A1;ABCG2;ABCB1;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP2C8;CYP1B1;CYP1A1;CYP2C9 GO:0043066| negative regulation of apoptotic process BECN1;ALB GO:0002576| platelet degranulation ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP3A5;CYP2C19;CYP2C8;CYP1B1;CYP2C9;NR1I2 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2C9;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP1A1;UGT1A1 32735:[DB06728 DB07385] DB06728|Aniline KLK1;ALB;CYP2E1 DB07385|3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE NQO1 common genes common pathways GO:0055114| oxidation-reduction process NQO1;CYP2E1 GO:0043066| negative regulation of apoptotic process NQO1;ALB GO:0006805| xenobiotic metabolic process NQO1;CYP2E1 GO:0045471| response to ethanol NQO1;CYP2E1 32736:[DB06728 DB00546] DB06728|Aniline KLK1;ALB;CYP2E1 DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0042493| response to drug GABRG3;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C19 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C19 32737:[DB06728 DB11254] DB06728|Aniline KLK1;ALB;CYP2E1 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 GO:0055114| oxidation-reduction process TYR;CYP2E1 32738:[DB06728 DB14700] DB06728|Aniline KLK1;ALB;CYP2E1 DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;F8 GO:0002576| platelet degranulation ALB;F8 32739:[DB06728 DB01158] DB06728|Aniline KLK1;ALB;CYP2E1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;CYP2E1 32740:[DB06728 DB09381] DB06728|Aniline KLK1;ALB;CYP2E1 DB09381|Estrogens, esterified CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 32741:[DB06728 DB02336] DB06728|Aniline KLK1;ALB;CYP2E1 DB02336|RU83876 SRC common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;SRC GO:0042493| response to drug SRC;CYP2E1 32742:[DB06728 DB00418] DB06728|Aniline KLK1;ALB;CYP2E1 DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C8;CYP2C19;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP1A2;CYP2E1 GO:0045471| response to ethanol GRIN3A;GRIN2A;GRIN1;GRIN2B;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;CYP2C9;CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP2C19;CYP2C8;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP1A2;CYP2E1 GO:0042493| response to drug GRIN2A;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP2C9;CYP2C19;CYP2C8 32743:[DB06728 DB06752] DB06728|Aniline KLK1;ALB;CYP2E1 DB06752|Chymopapain PRG2 common genes common pathways 32744:[DB06728 DB09095] DB06728|Aniline KLK1;ALB;CYP2E1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32745:[DB06728 DB02386] DB06728|Aniline KLK1;ALB;CYP2E1 DB02386|Leucine Phosphonic Acid LAP3 common genes common pathways GO:0006508| proteolysis KLK1;LAP3 32746:[DB06728 DB13345] DB06728|Aniline KLK1;ALB;CYP2E1 DB13345|Dihydroergocristine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD1;DRD5;DRD2;DRD3;DRD4;CYP3A4;ABCB11 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;HTR2B GO:0042493| response to drug DRD1;CYP2E1;HTR2A;ADRA1A;DRD2;HTR1B;HTR2B;HTR2C;DRD3 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol DRD3;HTR3A;HTR1B;DRD2;CYP2E1 GO:0006898| receptor-mediated endocytosis ALB;ADRB3;ADRB2 32747:[DB06728 DB07903] DB06728|Aniline KLK1;ALB;CYP2E1 DB07903|3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE METAP1 common genes common pathways GO:0006508| proteolysis KLK1;METAP1 32748:[DB06728 DB06558] DB06728|Aniline KLK1;ALB;CYP2E1 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways GO:0043066| negative regulation of apoptotic process EDNRB;ALB 32749:[DB06728 DB13915] DB06728|Aniline KLK1;ALB;CYP2E1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways 32750:[DB06728 DB06623] DB06728|Aniline KLK1;ALB;CYP2E1 DB06623|Flupirtine ADRA2A common genes common pathways 32751:[DB06728 DB05793] DB06728|Aniline KLK1;ALB;CYP2E1 DB05793|PRO-542 FFAR4 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;FFAR4 32752:[DB06728 DB09244] DB06728|Aniline KLK1;ALB;CYP2E1 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;MAOA 32753:[DB06728 DB00387] DB06728|Aniline KLK1;ALB;CYP2E1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways 32754:[DB06728 DB04081] DB06728|Aniline KLK1;ALB;CYP2E1 DB04081|(4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide CA2 common genes common pathways 32755:[DB06728 DB03270] DB06728|Aniline KLK1;ALB;CYP2E1 DB03270|2,6-Difluorobenzenesulfonamide CA2 common genes common pathways 32756:[DB06728 DB11718] DB06728|Aniline KLK1;ALB;CYP2E1 DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BRAF GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0010243| response to organic nitrogen CCND1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0042493| response to drug CYP2E1;CCND1 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0045471| response to ethanol CCND1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 32757:[DB06728 DB05133] DB06728|Aniline KLK1;ALB;CYP2E1 DB05133|VP025 IL1B common genes common pathways 32758:[DB06728 DB00956] DB06728|Aniline KLK1;ALB;CYP2E1 DB00956|Hydrocodone OPRM1;OPRD1;CYP2D6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0045471| response to ethanol OPRM1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 32759:[DB06728 DB01235] DB06728|Aniline KLK1;ALB;CYP2E1 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0042493| response to drug DRD3;DRD2;CYP2E1;DRD1 GO:0045471| response to ethanol CYP2E1;DRD2;DRD3 32760:[DB06728 DB03742] DB06728|Aniline KLK1;ALB;CYP2E1 DB03742|Compound 4-D ESR1 common genes common pathways 32761:[DB06728 DB02709] DB06728|Aniline KLK1;ALB;CYP2E1 DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes ALB common pathways GO:0006805| xenobiotic metabolic process CYP1B1;NR1I2;AHR;NQO2;PTGS1;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1 GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019373| epoxygenase P450 pathway CYP1A1;CYP1B1;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;SNCA;AKT1;PTGS2 GO:0002576| platelet degranulation APP;ALB;ITGB3 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug PPARG;CYP1A1;SNCA;PTGS2;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1B1;ALOX15;SNCA;NQO2;CYP1A1;ALOX5;PTGS1;CBR1;PTGS2;CYP1A2;CYP3A4;CYP2E1 GO:0043687| post-translational protein modification APP;ALB GO:0098869| PTGS1;PTGS2;ALB GO:0017144| drug metabolic process CYP1A1;CBR1;CYP2E1;CYP3A4;CYP1A2 GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;NR1I2;CYP1A1;CYP1B1 GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process TTR;APP;ALB;SNCA 32762:[DB06728 DB00590] DB06728|Aniline KLK1;ALB;CYP2E1 DB00590|Doxazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;CYP2C19;CYP2D6;CYP3A4;ORM1;ABCB1;SLC22A1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0002576| platelet degranulation ORM1;ALB GO:0055114| oxidation-reduction process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;ABCB1;ADRA1A GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 32763:[DB06728 DB01278] DB06728|Aniline KLK1;ALB;CYP2E1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways 32764:[DB06728 DB02721] DB06728|Aniline KLK1;ALB;CYP2E1 DB02721|4-Iodopyrazole ADH1C;ADH1B;ADH1A common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ADH1C;ADH1B;ADH1A GO:0017144| drug metabolic process ADH1A;CYP2E1 32765:[DB06728 DB01269] DB06728|Aniline KLK1;ALB;CYP2E1 DB01269|Panitumumab EGFR common genes common pathways GO:0043066| negative regulation of apoptotic process EGFR;ALB 32766:[DB06728 DB05053] DB06728|Aniline KLK1;ALB;CYP2E1 DB05053|MB-07803 FBP1 common genes common pathways 32767:[DB06728 DB01737] DB06728|Aniline KLK1;ALB;CYP2E1 DB01737|Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32768:[DB06728 DB09126] DB06728|Aniline KLK1;ALB;CYP2E1 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways 32769:[DB06728 DB00333] DB06728|Aniline KLK1;ALB;CYP2E1 DB00333|Methadone OPRM1;GRIN3A;CHRNA10;OPRD1;HTR3A;LY96;ORM2;CYP3A4;CYP2C19;CYP3A5;CYP3A7;CYP2D6;CYP2B6;CYP2C8;CYP19A1;CYP1A2;CYP2C18;CYP2C9;ABCB1 common genes common pathways GO:0002576| platelet degranulation ALB;ORM2 GO:0019373| epoxygenase P450 pathway CYP2C18;CYP1A2;CYP2E1;CYP2C19;CYP2C8;CYP2B6;CYP2C9 GO:0042493| response to drug ABCB1;CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP19A1;CYP2C8;CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C18 GO:0008202| steroid metabolic process CYP1A2;CYP3A7;CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP3A5;CYP2C19;CYP2C8;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0045471| response to ethanol HTR3A;GRIN3A;CYP2E1;OPRM1 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2C8;CYP2D6;CYP2C9;CYP2B6;CYP2C18;CYP2E1;CYP3A4;CYP1A2;CYP3A7 32770:[DB06728 DB05369] DB06728|Aniline KLK1;ALB;CYP2E1 DB05369|HZT-501 HRH2 common genes common pathways 32771:[DB06728 DB01348] DB06728|Aniline KLK1;ALB;CYP2E1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006508| proteolysis KLK1;ACE 32772:[DB06728 DB00961] DB06728|Aniline KLK1;ALB;CYP2E1 DB00961|Mepivacaine SCN10A common genes common pathways 32773:[DB06728 DB09054] DB06728|Aniline KLK1;ALB;CYP2E1 DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C19;CYP2C8;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP2C19;CYP2C8;CYP3A5;CYP2B6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;AOX1;CYP2B6;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;CYP3A5;CYP2B6;AOX1;CYP3A43;CYP3A7;CYP2E1;CYP3A4 GO:0042493| response to drug ABCG2;ABCB1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2B6;CYP2E1 32774:[DB06728 DB09186] DB06728|Aniline KLK1;ALB;CYP2E1 DB09186|Nisoxetine SLC6A4 common genes common pathways GO:0042493| response to drug CYP2E1;SLC6A4 32775:[DB06728 DB04703] DB06728|Aniline KLK1;ALB;CYP2E1 DB04703|Hesperidin AURKB common genes common pathways 32776:[DB06728 DB06825] DB06728|Aniline KLK1;ALB;CYP2E1 DB06825|Triptorelin GNRHR common genes common pathways 32777:[DB06728 DB07216] DB06728|Aniline KLK1;ALB;CYP2E1 DB07216|(11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE FNTA;FNTB common genes common pathways 32778:[DB06728 DB01941] DB06728|Aniline KLK1;ALB;CYP2E1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways 32779:[DB06728 DB01565] DB06728|Aniline KLK1;ALB;CYP2E1 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 32780:[DB06728 DB02096] DB06728|Aniline KLK1;ALB;CYP2E1 DB02096|FR221647 ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ADA;ALB GO:0042493| response to drug CYP2E1;ADA 32781:[DB06728 DB01611] DB06728|Aniline KLK1;ALB;CYP2E1 DB01611|Hydroxychloroquine TLR7;TLR9;CYP2D6;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 32782:[DB06728 DB14575] DB06728|Aniline KLK1;ALB;CYP2E1 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0045471| response to ethanol UGT1A1;CYP2E1 32783:[DB06728 DB01601] DB06728|Aniline KLK1;ALB;CYP2E1 DB01601|Lopinavir pol;CYP3A4;CYP2D6;CYP2C19;CYP2B6;CYP2C9;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP2B6;CYP2C9 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB GO:0017144| drug metabolic process CYP2D6;CYP2C19;CYP2C8;CYP2C9;CYP2B6;CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ABCB11;SLCO1B1;SLCO1B3;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2B6;CYP2C8;CYP2C19 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A4;CYP2E1;CYP3A43;CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP3A5 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2D6;CYP2C19;CYP2C8;CYP2C9;CYP2B6;CYP3A4;CYP2E1;CYP3A7 32784:[DB06728 DB01694] DB06728|Aniline KLK1;ALB;CYP2E1 DB01694|D-tartaric acid B3GAT1;TREM1;DDX6;HIF1AN;serA;lpxA;ATP6V1C1;phnA common genes common pathways GO:0055114| oxidation-reduction process HIF1AN;CYP2E1 32785:[DB06728 DB07514] DB06728|Aniline KLK1;ALB;CYP2E1 DB07514|3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one KDR common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;KDR 32786:[DB06728 DB09270] DB06728|Aniline KLK1;ALB;CYP2E1 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways GO:0006898| receptor-mediated endocytosis VLDLR;LDLR;ALB GO:0045471| response to ethanol HMGCR;CYP2E1 GO:0008202| steroid metabolic process HMGCR;VLDLR;CYP2E1;LDLR GO:0043066| negative regulation of apoptotic process HMGCR;ALB GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process NDUFV3;CYP2E1;SDHA;HMGCR 32787:[DB06728 DB13149] DB06728|Aniline KLK1;ALB;CYP2E1 DB13149|Protein S human F5;F10;PROC common genes common pathways GO:0002576| platelet degranulation ALB;F5 GO:0043066| negative regulation of apoptotic process PROC;ALB GO:0043687| post-translational protein modification ALB;F5;PROC GO:0044267| cellular protein metabolic process F5;ALB;PROC GO:0006508| proteolysis PROC;KLK1;F10 32788:[DB06728 DB12406] DB06728|Aniline KLK1;ALB;CYP2E1 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 32789:[DB06728 DB09199] DB06728|Aniline KLK1;ALB;CYP2E1 DB09199|Netoglitazone CYP3A4;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 32790:[DB06728 DB07393] DB06728|Aniline KLK1;ALB;CYP2E1 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways GO:0098869| GSR;ALB GO:0055114| oxidation-reduction process GSR;CYP2E1 32791:[DB06728 DB01839] DB06728|Aniline KLK1;ALB;CYP2E1 DB01839|Propylene glycol F13A1 common genes common pathways GO:0002576| platelet degranulation F13A1;ALB 32792:[DB06728 DB05675] DB06728|Aniline KLK1;ALB;CYP2E1 DB05675|EP-2104R FGA common genes common pathways GO:0044267| cellular protein metabolic process ALB;FGA GO:0002576| platelet degranulation FGA;ALB GO:0043687| post-translational protein modification FGA;ALB 32793:[DB06728 DB08996] DB06728|Aniline KLK1;ALB;CYP2E1 DB08996|Dimetacrine ACHE common genes common pathways 32794:[DB06728 DB02262] DB06728|Aniline KLK1;ALB;CYP2E1 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0042493| response to drug DHODH;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;DHODH 32795:[DB06728 DB03035] DB06728|Aniline KLK1;ALB;CYP2E1 DB03035|1,8-Di-Hydroxy-4-Nitro-Anthraquinone CSNK2A1 common genes common pathways 32796:[DB06728 DB01135] DB06728|Aniline KLK1;ALB;CYP2E1 DB01135|Doxacurium CHRNA2;CHRM2;BCHE common genes common pathways GO:0042493| response to drug BCHE;CYP2E1 32797:[DB06728 DB08084] DB06728|Aniline KLK1;ALB;CYP2E1 DB08084|IDD594 AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;AKR1B1 GO:0043066| negative regulation of apoptotic process ALB;AKR1B1 32798:[DB06728 DB03222] DB06728|Aniline KLK1;ALB;CYP2E1 DB03222|dATP POLB;recA;recA common genes common pathways GO:0045471| response to ethanol CYP2E1;POLB 32799:[DB06728 DB00327] DB06728|Aniline KLK1;ALB;CYP2E1 DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C9;CYP2E1;CYP3A4;PTGS1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;OPRM1;OPRK1 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2C9;UGT1A9;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process PTGS1;CYP2E1;CYP3A4;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 32800:[DB06728 DB04776] DB06728|Aniline KLK1;ALB;CYP2E1 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways 32801:[DB06728 DB02494] DB06728|Aniline KLK1;ALB;CYP2E1 DB02494|Alpha-Hydroxy-Beta-Phenyl-Propionic Acid RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13;CPA1 common genes common pathways GO:0045471| response to ethanol CYP2E1;RPL15 GO:0006508| proteolysis CPA1;KLK1 32802:[DB06728 DB07379] DB06728|Aniline KLK1;ALB;CYP2E1 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways 32803:[DB06728 DB05255] DB06728|Aniline KLK1;ALB;CYP2E1 DB05255|Ronacaleret CASR;ADGRF1 common genes common pathways 32804:[DB06728 DB08202] DB06728|Aniline KLK1;ALB;CYP2E1 DB08202|4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE CA2 common genes common pathways 32805:[DB06728 DB08439] DB06728|Aniline KLK1;ALB;CYP2E1 DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0098869| PTGS2;ALB GO:0017144| drug metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0044267| cellular protein metabolic process LTF;ALB GO:0043066| negative regulation of apoptotic process ALB;LTF;PTGS2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2E1;CYP2C9 GO:0001895| retina homeostasis LTF;ALB GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 GO:0006508| proteolysis KLK1;LTF 32806:[DB06728 DB08601] DB06728|Aniline KLK1;ALB;CYP2E1 DB08601|tributylstannanyl NCOA2;RXRA common genes common pathways GO:0015721| bile acid and bile salt transport RXRA;NCOA2;ALB 32807:[DB06728 DB07645] DB06728|Aniline KLK1;ALB;CYP2E1 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBB;HBA1 GO:0098869| HBA1;HBB;ALB 32808:[DB06728 DB04660] DB06728|Aniline KLK1;ALB;CYP2E1 DB04660|Choline alfoscerate GM2A common genes common pathways 32809:[DB06728 DB00073] DB06728|Aniline KLK1;ALB;CYP2E1 DB00073|Rituximab MS4A1 common genes common pathways 32810:[DB06728 DB06494] DB06728|Aniline KLK1;ALB;CYP2E1 DB06494|Sufugolix GNRHR common genes common pathways 32811:[DB06728 DB07108] DB06728|Aniline KLK1;ALB;CYP2E1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;BCL2L1 32812:[DB06728 DB08642] DB06728|Aniline KLK1;ALB;CYP2E1 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;CYP2E1 32813:[DB06728 DB09409] DB06728|Aniline KLK1;ALB;CYP2E1 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways GO:0042493| response to drug GRIN2A;CYP2E1 GO:0045471| response to ethanol CYP2E1;GRIN2B;GRIN1;GRIN2A;GRIN3A 32814:[DB06728 DB00048] DB06728|Aniline KLK1;ALB;CYP2E1 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways GO:0042493| response to drug COL1A1;CYP2E1 32815:[DB06728 DB00102] DB06728|Aniline KLK1;ALB;CYP2E1 DB00102|Becaplermin PDGFRB;PDGFRA;A2M common genes common pathways GO:0002576| platelet degranulation ALB;A2M GO:0043066| negative regulation of apoptotic process ALB;PDGFRB 32816:[DB06728 DB06967] DB06728|Aniline KLK1;ALB;CYP2E1 DB06967|6-ETHYL-5-[9-(3-METHOXYPROPYL)-9H-CARBAZOL-2-YL]PYRIMIDINE-2,4-DIAMINE REN common genes common pathways GO:0006508| proteolysis REN;KLK1 GO:0042493| response to drug CYP2E1;REN 32817:[DB06728 DB05239] DB06728|Aniline KLK1;ALB;CYP2E1 DB05239|Cobimetinib MAP2K1;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0042493| response to drug ABCG2;ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 32818:[DB06728 DB00941] DB06728|Aniline KLK1;ALB;CYP2E1 DB00941|Hexafluronium BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 32819:[DB06728 DB02910] DB06728|Aniline KLK1;ALB;CYP2E1 DB02910|Octanoyl-Coenzyme A ECHS1;ECI1;ACADM common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;ACADM 32820:[DB06728 DB02830] DB06728|Aniline KLK1;ALB;CYP2E1 DB02830|FR236913 ADA common genes common pathways GO:0042493| response to drug ADA;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;ADA 32821:[DB06728 DB02388] DB06728|Aniline KLK1;ALB;CYP2E1 DB02388|Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine MAPK10 common genes common pathways 32822:[DB06728 DB03127] DB06728|Aniline KLK1;ALB;CYP2E1 DB03127|Benzamidine KLK6;PRSS2;PRSS3;ATOX1;ECI1;ST14;PLAU;PRSS1;CSNK2A1;KLK1 common genes KLK1 common pathways GO:0006508| proteolysis KLK1;ST14;PRSS3;KLK6;PLAU;PRSS1;PRSS2 32823:[DB06728 DB02703] DB06728|Aniline KLK1;ALB;CYP2E1 DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0042493| response to drug CYP2E1;ABCG2;ABCC2;UGT1A1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;ABCB11 32824:[DB06728 DB04581] DB06728|Aniline KLK1;ALB;CYP2E1 DB04581|1-benzylimidazole QPCT common genes common pathways 32825:[DB06728 DB02046] DB06728|Aniline KLK1;ALB;CYP2E1 DB02046|N-[(Furan-2-Yl)Carbonyl]-(S)-Leucyl-(R)-[1-Amino-2(1h-Indol-3-Yl)Ethyl]-Phosphonic Acid ADAM28 common genes common pathways GO:0006508| proteolysis ADAM28;KLK1 32826:[DB06728 DB06264] DB06728|Aniline KLK1;ALB;CYP2E1 DB06264|Tolperisone CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1 GO:0042493| response to drug CYP2E1;CYP1A2 32827:[DB06728 DB02989] DB06728|Aniline KLK1;ALB;CYP2E1 DB02989|CRA_10972 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32828:[DB06728 DB00068] DB06728|Aniline KLK1;ALB;CYP2E1 DB00068|Interferon beta-1b IFNAR1;IFNAR2 common genes common pathways 32829:[DB06728 DB00518] DB06728|Aniline KLK1;ALB;CYP2E1 DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;CYP1A1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP1A1;CYP1A2;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2C19;CYP1A1 GO:0055114| oxidation-reduction process CYP2C19;CYP1A1;CYP3A4;CYP2E1;CYP1A2 GO:0042493| response to drug CYP1A1;ABCB1;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP1A1;CYP1A2;CYP2E1 32830:[DB06728 DB13835] DB06728|Aniline KLK1;ALB;CYP2E1 DB13835|Caroverine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 32831:[DB06728 DB08378] DB06728|Aniline KLK1;ALB;CYP2E1 DB08378|4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID MYL6B;MYL12A;MYH7 common genes common pathways 32832:[DB06728 DB01227] DB06728|Aniline KLK1;ALB;CYP2E1 DB01227|Levacetylmethadol OPRM1;CHRNB4;CHRNA3;CYP3A5;CYP3A7;CYP3A4;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP3A7;CYP19A1;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5 GO:0006805| xenobiotic metabolic process CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0045471| response to ethanol CYP2E1;OPRM1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 32833:[DB06728 DB01699] DB06728|Aniline KLK1;ALB;CYP2E1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0042493| response to drug CYP2E1;ABAT GO:0045471| response to ethanol ABAT;CYP2E1 32834:[DB06728 DB00268] DB06728|Aniline KLK1;ALB;CYP2E1 DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug DRD1;CYP1A2;CYP2E1;HTR2A;DRD2;HTR1B;HTR2C;HTR2B;DRD3 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process HTR2B;ALB GO:0045471| response to ethanol CYP2E1;DRD3;DRD2;HTR1B GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP1A2;CYP2D6 32835:[DB06728 DB01196] DB06728|Aniline KLK1;ALB;CYP2E1 DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 32836:[DB06728 DB06937] DB06728|Aniline KLK1;ALB;CYP2E1 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways 32837:[DB06728 DB07800] DB06728|Aniline KLK1;ALB;CYP2E1 DB07800|N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE F10 common genes common pathways GO:0006508| proteolysis KLK1;F10 32838:[DB06728 DB08169] DB06728|Aniline KLK1;ALB;CYP2E1 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0042493| response to drug DHODH;CYP2E1 GO:0055114| oxidation-reduction process DHODH;CYP2E1 32839:[DB06728 DB11362] DB06728|Aniline KLK1;ALB;CYP2E1 DB11362|Selexipag PTGIR;CES1;CYP2C8;CYP3A4;SLCO1B1;SLCO1B3;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2E1;CYP3A4;CES1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2C8 GO:0042493| response to drug CYP2E1;ABCB1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB GO:0017144| drug metabolic process CYP2C8;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2C8 GO:0043252| sodium-independent organic anion transport SLCO1B1;SLCO1B3;ALB 32840:[DB06728 DB01039] DB06728|Aniline KLK1;ALB;CYP2E1 DB01039|Fenofibrate PPARA;PPARG;PPARD;NR1I2;CYP2C8;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0015721| bile acid and bile salt transport ABCB11;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;NR1I2;UGT1A1;CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C9;CYP2C8 GO:0042493| response to drug UGT1A1;PPARG;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;PPARD GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C9;NR1I2;CYP3A4;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1;CYP3A4 32841:[DB06728 DB06263] DB06728|Aniline KLK1;ALB;CYP2E1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0006805| xenobiotic metabolic process POR;CYP2E1 GO:0055114| oxidation-reduction process POR;CBR1;CYP2E1 GO:0042493| response to drug CYP2E1;POR GO:0043066| negative regulation of apoptotic process POR;ALB GO:0017144| drug metabolic process CBR1;CYP2E1 32842:[DB06728 DB00186] DB06728|Aniline KLK1;ALB;CYP2E1 DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process UGT2B15;CYP3A4;TSPO;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug GABRG3;TSPO;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;UGT2B15 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 32843:[DB06728 DB08709] DB06728|Aniline KLK1;ALB;CYP2E1 DB08709|2,3-diphenyl-1H-indole-7-carboxylic acid PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PIM1 32844:[DB06728 DB03725] DB06728|Aniline KLK1;ALB;CYP2E1 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways 32845:[DB06728 DB06938] DB06728|Aniline KLK1;ALB;CYP2E1 DB06938|4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;ALB 32846:[DB06728 DB05710] DB06728|Aniline KLK1;ALB;CYP2E1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways 32847:[DB06728 DB08301] DB06728|Aniline KLK1;ALB;CYP2E1 DB08301|N-({[4-(AMINOSULFONYL)PHENYL]AMINO}CARBONYL)-4-METHYLBENZENESULFONAMIDE CA2 common genes common pathways 32848:[DB06728 DB04898] DB06728|Aniline KLK1;ALB;CYP2E1 DB04898|Ximelagatran F2;CYP2C9 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0044267| cellular protein metabolic process ALB;F2 GO:0017144| drug metabolic process CYP2E1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2E1 32849:[DB06728 DB00426] DB06728|Aniline KLK1;ALB;CYP2E1 DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;AOX1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;AOX1 32850:[DB06728 DB06809] DB06728|Aniline KLK1;ALB;CYP2E1 DB06809|Plerixafor CXCR4 common genes common pathways 32851:[DB06728 DB14545] DB06728|Aniline KLK1;ALB;CYP2E1 DB14545|Hydrocortisone succinate CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP11B1;CYP11B2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0055114| oxidation-reduction process CYP3A7;CYP11B2;CYP11B1;CYP2E1;CYP3A4;CYP3A5;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP11B1;CYP11B2;CYP3A7;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C8 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2C8 32852:[DB06728 DB02740] DB06728|Aniline KLK1;ALB;CYP2E1 DB02740|3-Indolebutyric Acid tyrB;B2M;TRAC;TRBC1;HLA-A common genes common pathways GO:0042493| response to drug CYP2E1;B2M GO:0044267| cellular protein metabolic process B2M;ALB GO:0001895| retina homeostasis B2M;ALB 32853:[DB06728 DB09068] DB06728|Aniline KLK1;ALB;CYP2E1 DB09068|Vortioxetine SLC6A4;HTR3A;HTR7;HTR1B;HTR1A;ADRB1;CYP2D6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2A6;CYP2C8;CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2A6;CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2D6 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP2E1;CYP2A6 GO:0042493| response to drug HTR1B;CYP2E1;SLC6A4 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;CYP3A5;CYP2B6;CYP2C9;CYP2A6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2D6;CYP2C19 GO:0045471| response to ethanol CYP2E1;HTR1B;HTR3A GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP3A5;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6 32854:[DB06728 DB03173] DB06728|Aniline KLK1;ALB;CYP2E1 DB03173|CRA_10433 PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 32855:[DB06728 DB02165] DB06728|Aniline KLK1;ALB;CYP2E1 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways 32856:[DB06728 DB01082] DB06728|Aniline KLK1;ALB;CYP2E1 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 32857:[DB06728 DB02824] DB06728|Aniline KLK1;ALB;CYP2E1 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways 32858:[DB06728 DB06757] DB06728|Aniline KLK1;ALB;CYP2E1 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0001895| retina homeostasis ALB;TF GO:0002576| platelet degranulation TF;ALB GO:0055114| oxidation-reduction process IDH3A;IDH3G;CYP2E1 GO:0043687| post-translational protein modification TF;ALB GO:0042493| response to drug CYP2E1;ARG1 GO:0044267| cellular protein metabolic process TF;ALB 32859:[DB06728 DB06878] DB06728|Aniline KLK1;ALB;CYP2E1 DB06878|1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 32860:[DB06728 DB14526] DB06728|Aniline KLK1;ALB;CYP2E1 DB14526|Chromic citrate CYB5A;TF common genes common pathways GO:0002576| platelet degranulation ALB;TF GO:0043687| post-translational protein modification ALB;TF GO:0055114| oxidation-reduction process CYB5A;CYP2E1 GO:0044267| cellular protein metabolic process ALB;TF GO:0001895| retina homeostasis ALB;TF 32861:[DB06728 DB01140] DB06728|Aniline KLK1;ALB;CYP2E1 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport SLC22A8;SLC22A6;ALB 32862:[DB06728 DB12161] DB06728|Aniline KLK1;ALB;CYP2E1 DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;CYP3A4;CBR3;CYP2D6;CYP3A5 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP3A5 GO:0017144| drug metabolic process CYP2D6;CBR1;CYP3A4;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CBR3;CYP2E1;CYP3A4;CYP1A2;CBR1 32863:[DB06728 DB00121] DB06728|Aniline KLK1;ALB;CYP2E1 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP1B1 GO:0055114| oxidation-reduction process CYP2E1;CYP1B1 GO:0042493| response to drug CYP2E1;ACACB GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2E1 GO:0008202| steroid metabolic process CYP1B1;CYP2E1 32864:[DB06728 DB05432] DB06728|Aniline KLK1;ALB;CYP2E1 DB05432|DAS-431 IV CALY common genes common pathways 32865:[DB06728 DB08909] DB06728|Aniline KLK1;ALB;CYP2E1 DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 32866:[DB06728 DB03443] DB06728|Aniline KLK1;ALB;CYP2E1 DB03443|Bis(5-Amidino-Benzimidazolyl)Methanone Zinc PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32867:[DB06728 DB13125] DB06728|Aniline KLK1;ALB;CYP2E1 DB13125|Lusutrombopag MPL;CYP4A11;ABCB1;ABCG2 common genes common pathways GO:0055114| oxidation-reduction process CYP4A11;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB1;ABCG2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP4A11 32868:[DB06728 DB01201] DB06728|Aniline KLK1;ALB;CYP2E1 DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C8;CYP2C19;CYP2B6;CYP2C9;CYP3A43;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP2C9;CYP2B6;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2B6;CYP2C8;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4 32869:[DB06728 DB05389] DB06728|Aniline KLK1;ALB;CYP2E1 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways GO:0006898| receptor-mediated endocytosis CD163;ALB 32870:[DB06728 DB00688] DB06728|Aniline KLK1;ALB;CYP2E1 DB00688|Mycophenolate mofetil IMPDH1;IMPDH2;UGT1A1;UGT1A7;UGT1A6;UGT1A9;UGT2B7;UGT1A8;UGT1A10;CES1;CES2;CYP3A4;CYP3A5;CYP2C8;ALB;SLCO1B1;SLCO1B3;ABCC2;ABCG2;ABCB1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 GO:0044267| cellular protein metabolic process ALB GO:0017144| drug metabolic process CYP2C8;UGT1A8;UGT1A9;UGT1A1;UGT1A6;UGT1A10;UGT1A7;CYP3A4;CYP2E1 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO1B3;SLCO1B1;ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT2B7;UGT1A8;UGT1A1;CYP2C8;CYP3A5 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process IMPDH2;CYP2E1;CYP3A4;CYP2C8;CYP3A5;IMPDH1 GO:0042493| response to drug CYP2E1;ABCC2;ABCG2;ABCB1;UGT1A1 GO:0002576| platelet degranulation ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0006898| receptor-mediated endocytosis ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006805| xenobiotic metabolic process UGT1A9;CES2;CYP3A5;CYP2C8;CYP2E1;CYP3A4;CES1;UGT1A6 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB 32871:[DB06728 DB04901] DB06728|Aniline KLK1;ALB;CYP2E1 DB04901|Galiximab CD80 common genes common pathways 32872:[DB06728 DB04574] DB06728|Aniline KLK1;ALB;CYP2E1 DB04574|Estrone sulfate ESR1;ESR2;CYP3A4;CYP1A2;CYP2C9;SHBG;ALB;SLC47A1;SLC47A2 common genes ALB common pathways GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C9;CYP1A2;CYP2E1 GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP2C9 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C9 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C9 GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP1A2;CYP3A4;CYP2E1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB 32873:[DB06728 DB06393] DB06728|Aniline KLK1;ALB;CYP2E1 DB06393|Xaliproden HTR1A common genes common pathways 32874:[DB06728 DB00747] DB06728|Aniline KLK1;ALB;CYP2E1 DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 GO:0045471| response to ethanol CYP2E1;CHRNB2 32875:[DB06728 DB04173] DB06728|Aniline KLK1;ALB;CYP2E1 DB04173|Fructose FHIT common genes common pathways 32876:[DB06728 DB01117] DB06728|Aniline KLK1;ALB;CYP2E1 DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways GO:0045471| response to ethanol CYP2E1;MT-CYB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;DHODH;CYP2C9;MT-CYB GO:0042493| response to drug DHODH;CYP2E1;MT-CYB GO:0010243| response to organic nitrogen MT-CYB;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2E1 32877:[DB06728 DB12582] DB06728|Aniline KLK1;ALB;CYP2E1 DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2C9;NR1I2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;NR1I2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2E1 32878:[DB06728 DB04855] DB06728|Aniline KLK1;ALB;CYP2E1 DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes ALB common pathways GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0008202| steroid metabolic process CYP2D6;CYP2E1;CYP3A4 GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0042493| response to drug ABCB1;ADRA1A;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1;CYP3A4 GO:0043687| post-translational protein modification ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2D6;CYP3A4;CYP2E1 32879:[DB06728 DB04213] DB06728|Aniline KLK1;ALB;CYP2E1 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;EPHX2 GO:0019373| epoxygenase P450 pathway CYP2E1;EPHX2 GO:0017144| drug metabolic process CYP2E1;EPHX2 32880:[DB06728 DB02869] DB06728|Aniline KLK1;ALB;CYP2E1 DB02869|3-amino-5-phenylpentane CTSV;CTSK common genes common pathways GO:0006508| proteolysis CTSV;KLK1;CTSK GO:0009267| cellular response to starvation ALB;CTSV 32881:[DB06728 DB03722] DB06728|Aniline KLK1;ALB;CYP2E1 DB03722|3,4-Dihydro-5-Methyl-Isoquinolinone PARP1 common genes common pathways 32882:[DB06728 DB07232] DB06728|Aniline KLK1;ALB;CYP2E1 DB07232|Veliparib PARP1;PARP2 common genes common pathways 32883:[DB06728 DB05855] DB06728|Aniline KLK1;ALB;CYP2E1 DB05855|Rivanicline CHRNB2;CXCL8 common genes common pathways GO:0045471| response to ethanol CYP2E1;CHRNB2 32884:[DB06728 DB13909] DB06728|Aniline KLK1;ALB;CYP2E1 DB13909|Bismuth subgallate ALB common genes ALB common pathways GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0043687| post-translational protein modification ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 32885:[DB06728 DB03893] DB06728|Aniline KLK1;ALB;CYP2E1 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways GO:0055114| oxidation-reduction process GAPDH;CYP2E1 32886:[DB06728 DB08262] DB06728|Aniline KLK1;ALB;CYP2E1 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HBB;HBA1 GO:0098869| HBB;HBA1;ALB 32887:[DB06728 DB08745] DB06728|Aniline KLK1;ALB;CYP2E1 DB08745|4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 32888:[DB06728 DB00343] DB06728|Aniline KLK1;ALB;CYP2E1 DB00343|Diltiazem CACNG1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2D6;CYP2C8;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP2D6;CYP3A5;CYP2E1;CYP3A4;CYP3A7 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process CYP2D6;CYP2C19;CYP2C8;CYP3A5;CYP3A4;CYP2E1;CYP3A7 GO:0042493| response to drug CYP2E1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP3A7;CYP3A5;CYP2D6;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A4 32889:[DB06728 DB07519] DB06728|Aniline KLK1;ALB;CYP2E1 DB07519|(6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis BACE1;KLK1 32890:[DB06728 DB01922] DB06728|Aniline KLK1;ALB;CYP2E1 DB01922|Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam AMY2A;AMY2A common genes common pathways 32891:[DB06728 DB05122] DB06728|Aniline KLK1;ALB;CYP2E1 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways 32892:[DB06728 DB02585] DB06728|Aniline KLK1;ALB;CYP2E1 DB02585|4-(Hydroxymethyl)Benzamidine PRSS3 common genes common pathways GO:0006508| proteolysis KLK1;PRSS3 32893:[DB06728 DB04065] DB06728|Aniline KLK1;ALB;CYP2E1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0017144| drug metabolic process CYP2E1;ADH1A GO:0055114| oxidation-reduction process CYP2E1;ADH1A 32894:[DB06728 DB09075] DB06728|Aniline KLK1;ALB;CYP2E1 DB09075|Edoxaban F10;ABCB1 common genes common pathways GO:0006508| proteolysis F10;KLK1 GO:0042493| response to drug CYP2E1;ABCB1 32895:[DB06728 DB04720] DB06728|Aniline KLK1;ALB;CYP2E1 DB04720|S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways 32896:[DB06728 DB04002] DB06728|Aniline KLK1;ALB;CYP2E1 DB04002|4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide CA2 common genes common pathways 32897:[DB06728 DB00844] DB06728|Aniline KLK1;ALB;CYP2E1 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1 32898:[DB06728 DB00624] DB06728|Aniline KLK1;ALB;CYP2E1 DB00624|Testosterone AR;ESR1;NR3C2;CYP3A5;CYP19A1;CYP11A1;MAOA;CYP3A7;CYP3A4;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes ALB common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A1;CYP2C19 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2A13;CYP3A4;CYP3A7;CYP2C19;CYP2C8;CYP3A5;CYP1B1;CYP2B6;CYP2C9 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 GO:0042493| response to drug ABCB1;ABCG2;CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process MAOA;CYP3A7;CYP11A1;CYP2A13;CYP2E1;CYP3A4;CYP3A43;CYP2B6;CYP1A1;CYP2C9;CYP19A1;CYP1B1;CYP2C8;CYP2C19;CYP3A5 GO:0043687| post-translational protein modification ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2C8;CYP1B1;CYP2B6;CYP2C9;CYP1A1;CYP2E1;CYP2A13 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;ALB;SLC10A1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP11A1;CYP3A7;CYP2C9;CYP1A1;CYP2B6;CYP3A5;CYP2C19;CYP2C8;CYP1B1 GO:0043252| sodium-independent organic anion transport SLC22A8;SLCO1A2;SLC22A7;ALB GO:0009267| cellular response to starvation ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A1;CYP2C9;CYP2B6;CYP2C19;CYP2C8 32899:[DB06728 DB07965] DB06728|Aniline KLK1;ALB;CYP2E1 DB07965|6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)-ethyl]-9H-purine-2-carbonitrile CTSK common genes common pathways GO:0006508| proteolysis KLK1;CTSK 32900:[DB06728 DB08689] DB06728|Aniline KLK1;ALB;CYP2E1 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways GO:0055114| oxidation-reduction process SDHC;CYP2E1;SDHA;SDHD;SDHB 32901:[DB06728 DB01112] DB06728|Aniline KLK1;ALB;CYP2E1 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways 32902:[DB06728 DB04453] DB06728|Aniline KLK1;ALB;CYP2E1 DB04453|4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose AMY2A;AMY2A common genes common pathways 32903:[DB06728 DB00934] DB06728|Aniline KLK1;ALB;CYP2E1 DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP1A2;CYP2E1 GO:0042493| response to drug ADRA1A;DRD2;HTR2C;SLC6A2;CYP1A2;HTR2A;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2;CYP2D6 GO:0002576| platelet degranulation ORM1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2D6;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP1A2;CYP2D6 GO:0045471| response to ethanol CYP2E1;DRD2 32904:[DB06728 DB05079] DB06728|Aniline KLK1;ALB;CYP2E1 DB05079|HY10275 HRH1;HTR2A common genes common pathways GO:0042493| response to drug CYP2E1;HTR2A 32905:[DB06728 DB05403] DB06728|Aniline KLK1;ALB;CYP2E1 DB05403|CEP-1347 MAPK12 common genes common pathways 32906:[DB06728 DB05961] DB06728|Aniline KLK1;ALB;CYP2E1 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways GO:0002576| platelet degranulation SERPING1;ALB;SERPINA1 GO:0043687| post-translational protein modification SERPINA1;ALB GO:0044267| cellular protein metabolic process ALB;SERPINA1 32907:[DB06728 DB04982] DB06728|Aniline KLK1;ALB;CYP2E1 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways 32908:[DB06728 DB11386] DB06728|Aniline KLK1;ALB;CYP2E1 DB11386|Chlorobutanol KCNH2 common genes common pathways 32909:[DB06728 DB06021] DB06728|Aniline KLK1;ALB;CYP2E1 DB06021|AV-412 EGFR;ERBB2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;EGFR 32910:[DB06728 DB04869] DB06728|Aniline KLK1;ALB;CYP2E1 DB04869|Olcegepant CALCA;CALCRL common genes common pathways 32911:[DB06728 DB00932] DB06728|Aniline KLK1;ALB;CYP2E1 DB00932|Tipranavir pol;CYP3A4;CYP2D6;CYP2C19;UGT1A1;ABCB11;SLCO2B1;SLCO1B1;SLCO1B3 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;UGT1A1;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2D6 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1B1;SLCO1B3 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6;CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2D6;CYP2E1;CYP3A4 GO:0015721| bile acid and bile salt transport SLCO2B1;ALB;ABCB11;SLCO1B1;SLCO1B3 32912:[DB06728 DB13951] DB06728|Aniline KLK1;ALB;CYP2E1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process HSD17B1;CYP2E1;CYP11A1;CYP17A1;CYP19A1 GO:0008202| steroid metabolic process CYP11A1;CYP2E1;CYP17A1 32913:[DB06728 DB14003] DB06728|Aniline KLK1;ALB;CYP2E1 DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;VLDLR;CYP2E1;LDLR;APOBR GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP4F2 GO:0055114| oxidation-reduction process CYP4F2;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP4F2;CYP2E1 GO:0034375| high-density lipoprotein particle remodeling SCARB1;ALB GO:0006641| triglyceride metabolic process APOBR;CYP2E1 GO:0006898| receptor-mediated endocytosis LDLR;ALB;APOBR;SCARB1;VLDLR GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 32914:[DB06728 DB09128] DB06728|Aniline KLK1;ALB;CYP2E1 DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1 GO:0042493| response to drug DRD2;HTR2A;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol CYP2E1;DRD2 GO:0016098| monoterpenoid metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2D6 32915:[DB06728 DB02288] DB06728|Aniline KLK1;ALB;CYP2E1 DB02288|CRA_9334 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32916:[DB06728 DB09202] DB06728|Aniline KLK1;ALB;CYP2E1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug CYP2E1;ADRA1A 32917:[DB06728 DB09161] DB06728|Aniline KLK1;ALB;CYP2E1 DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1;ABCB1 32918:[DB06728 DB11642] DB06728|Aniline KLK1;ALB;CYP2E1 DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP2B6;CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP2B6;CYP2E1;CYP3A4;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2B6;CYP2D6;CYP1A2;CYP3A4;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2B6;CYP3A4;CYP2E1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2;CYP2D6 32919:[DB06728 DB00141] DB06728|Aniline KLK1;ALB;CYP2E1 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways 32920:[DB06728 DB03904] DB06728|Aniline KLK1;ALB;CYP2E1 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways GO:0042493| response to drug ARG1;CTNNB1;CYP2E1 32921:[DB06728 DB07177] DB06728|Aniline KLK1;ALB;CYP2E1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PTGR2;PTGR1 32922:[DB06728 DB03793] DB06728|Aniline KLK1;ALB;CYP2E1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0043066| negative regulation of apoptotic process PRDX5;ALB GO:0055114| oxidation-reduction process DAO;PRDX5;CYP2E1 GO:0098869| PRDX5;ALB GO:0043252| sodium-independent organic anion transport SLC22A8;ALB;SLCO2B1 GO:0015721| bile acid and bile salt transport ALB;SLCO2B1 32923:[DB06728 DB02925] DB06728|Aniline KLK1;ALB;CYP2E1 DB02925|Piretanide SLC12A1 common genes common pathways 32924:[DB06728 DB08232] DB06728|Aniline KLK1;ALB;CYP2E1 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways GO:0006508| proteolysis F7;KLK1 32925:[DB06728 DB13501] DB06728|Aniline KLK1;ALB;CYP2E1 DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 32926:[DB06728 DB00603] DB06728|Aniline KLK1;ALB;CYP2E1 DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C9 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C9;CYP2C8 GO:0055114| oxidation-reduction process CYP2C9;CYP2C8;CYP3A4;CYP2E1;HSD3B2 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2C8;CYP2E1;CYP3A4 32927:[DB06728 DB02731] DB06728|Aniline KLK1;ALB;CYP2E1 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways GO:0045471| response to ethanol OXCT1;CYP2E1 GO:0042493| response to drug OXCT1;CYP2E1 32928:[DB06728 DB07984] DB06728|Aniline KLK1;ALB;CYP2E1 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0098869| ALB;PTGS1 GO:0055114| oxidation-reduction process CYP2E1;PTGS1 GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 32929:[DB06728 DB13892] DB06728|Aniline KLK1;ALB;CYP2E1 DB13892|Crotalus atrox antivenin PLA2G10;CYP4A11 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP4A11 GO:0019373| epoxygenase P450 pathway CYP4A11;CYP2E1 32930:[DB06728 DB06480] DB06728|Aniline KLK1;ALB;CYP2E1 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes ALB common pathways GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0098869| ALB GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0002576| platelet degranulation ALB GO:0043066| negative regulation of apoptotic process ALB GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043687| post-translational protein modification ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 32931:[DB06728 DB04216] DB06728|Aniline KLK1;ALB;CYP2E1 DB04216|Quercetin HCK;PIK3CG;UGT3A1;ATP5B;PIM1;HIBCH;fabZ;STK17B;ESR1;ESR2;NQO2;AHR;CYP1B1;ACTB;CSNK2A1;CSNK2B;EIF3F;HSP90AA1;HSPA2;RUVBL2;SF3B3;UBA1;SHBG;CBR1;CEBPB;NR1I2;CYP2C8;ALB;ABCC1;ABCC2;SLC16A7;SLCO2B1;ABCB1;SLC16A1;ABCG2;SLCO1B1 common genes ALB common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1B1;CYP2C8 GO:0043066| negative regulation of apoptotic process ALB;HCK;PIM1 GO:0002576| platelet degranulation ALB GO:0055114| oxidation-reduction process NQO2;CYP1B1;CYP2C8;CYP2E1;CBR1 GO:0043687| post-translational protein modification ALB GO:0042493| response to drug ABCG2;ABCC2;ABCB1;ABCC1;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CBR1;CYP2E1 GO:0098869| ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport SLCO2B1;ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP2C8;CYP1B1;NR1I2;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO2B1;ALB GO:0044267| cellular protein metabolic process ALB GO:0006805| xenobiotic metabolic process CYP1B1;CYP2C8;AHR;NQO2;NR1I2;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006508| proteolysis EIF3F;KLK1 GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0001895| retina homeostasis ALB;ACTB GO:0034375| high-density lipoprotein particle remodeling ALB 32932:[DB06728 DB07983] DB06728|Aniline KLK1;ALB;CYP2E1 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;PTGS1 GO:0055114| oxidation-reduction process CYP2E1;PTGS1 GO:0098869| PTGS1;ALB 32933:[DB06728 DB13293] DB06728|Aniline KLK1;ALB;CYP2E1 DB13293|Ipecac CYP2D6;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2D6 32934:[DB06728 DB01616] DB06728|Aniline KLK1;ALB;CYP2E1 DB01616|Alverine HTR1A common genes common pathways 32935:[DB06728 DB07769] DB06728|Aniline KLK1;ALB;CYP2E1 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways 32936:[DB06728 DB00472] DB06728|Aniline KLK1;ALB;CYP2E1 DB00472|Fluoxetine SLC6A4;KCNH2;HTR2C;CKS1B;CHRNA2;CHRNA3;CHRNB4;CYP2C19;CYP2D6;CYP2C9;CYP2B;CYP1A2;CYP3A4;CYP2B6;CYP3A5;ALB;ORM1;ABCB1 common genes ALB common pathways GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB GO:0098869| ALB GO:0017144| drug metabolic process CYP2C19;CYP2D6;CYP2B6;CYP2C9;CYP2E1;CYP3A4;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP3A5;CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0042493| response to drug HTR2C;ABCB1;CYP2E1;CYP1A2;SLC6A4 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP3A5;CYP2D6;CYP2C19;CYP2C9;CYP2B6 GO:0002576| platelet degranulation ALB;ORM1 GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2B6;CYP2C9;CYP2E1;CYP1A2 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP3A5 GO:0046483| heterocycle metabolic process CYP2D6;CYP2C19;CYP1A2;CYP3A4;CYP2E1 GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP3A4;CYP2C19;CYP2D6;CYP2C9 32937:[DB06728 DB01250] DB06728|Aniline KLK1;ALB;CYP2E1 DB01250|Olsalazine TPMT;IFNG common genes common pathways 32938:[DB06728 DB00881] DB06728|Aniline KLK1;ALB;CYP2E1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 GO:0006508| proteolysis KLK1;ACE 32939:[DB06728 DB07454] DB06728|Aniline KLK1;ALB;CYP2E1 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways 32940:[DB06728 DB08489] DB06728|Aniline KLK1;ALB;CYP2E1 DB08489|N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YL)-SUCCINAMIDE MMP7 common genes common pathways GO:0006508| proteolysis MMP7;KLK1 32941:[DB06728 DB09117] DB06728|Aniline KLK1;ALB;CYP2E1 DB09117|Paraldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process ALDH2;CYP2E1 32942:[DB06728 DB00170] DB06728|Aniline KLK1;ALB;CYP2E1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes CYP2E1 common pathways GO:0010193| response to ozone CYP2E1 GO:0044267| cellular protein metabolic process PROC;ALB;F2 GO:0017144| drug metabolic process VKORC1;CYP1A2;CYP2A6;CYP2E1;AOX1;CYP1A1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2A6;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1 GO:0042493| response to drug CYP1A1;CYP1A2;MTHFR;CYP2E1 GO:0043687| post-translational protein modification PROC;ALB GO:0055114| oxidation-reduction process CYP2A6;CYP2E1;MTHFR;XDH;VKORC1;CYP1A2;VKORC1L1;AOX1;CYP1A1;NQO1;NQO2 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2A6;CYP2E1;CYP1A2 GO:0043066| negative regulation of apoptotic process PROC;ALB;NQO1 GO:0002576| platelet degranulation ALB;PROS1 GO:0018910| benzene metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006508| proteolysis PROC;KLK1;F9;PROZ;F10;F7;F2 GO:0006805| xenobiotic metabolic process NQO2;NQO1;CYP1A2;CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP1A2;CYP2E1 GO:0045471| response to ethanol CYP2E1;NQO1 32943:[DB06728 DB06403] DB06728|Aniline KLK1;ALB;CYP2E1 DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;CYP3A5;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0043066| negative regulation of apoptotic process EDNRB;ALB GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 GO:0017144| drug metabolic process UGT1A3;CYP2E1;CYP3A4;CYP2C19;UGT1A9 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1B3 GO:0008202| steroid metabolic process CYP3A5;CYP2C19;UGT2B7;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process UGT1A9;CYP2C19;CYP3A5;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 32944:[DB06728 DB08577] DB06728|Aniline KLK1;ALB;CYP2E1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways 32945:[DB06728 DB01333] DB06728|Aniline KLK1;ALB;CYP2E1 DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 32946:[DB06728 DB07347] DB06728|Aniline KLK1;ALB;CYP2E1 DB07347|4-(2-Aminoethyl)Benzenesulfonyl Fluoride GAPDH;ATP6V1B2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;GAPDH 32947:[DB06728 DB01339] DB06728|Aniline KLK1;ALB;CYP2E1 DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCB1 32948:[DB06728 DB03891] DB06728|Aniline KLK1;ALB;CYP2E1 DB03891|1,5-Bis(N-Benzyloxycarbonyl-L-Leucinyl)Carbohydrazide CTSK common genes common pathways GO:0006508| proteolysis CTSK;KLK1 32949:[DB06728 DB08420] DB06728|Aniline KLK1;ALB;CYP2E1 DB08420|1-{[1-(2-AMINO-3-PHENYL-PROPIONYL)-PYRROLIDINE-2-CARBONYL]-AMINO}-2-(3-CYANO-PHENYL)-ETHANEBORONIC ACID PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 32950:[DB06728 DB05214] DB06728|Aniline KLK1;ALB;CYP2E1 DB05214|KD7040 NOS2 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;NOS2 32951:[DB06728 DB03468] DB06728|Aniline KLK1;ALB;CYP2E1 DB03468|1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide PNMT common genes common pathways 32952:[DB06728 DB07316] DB06728|Aniline KLK1;ALB;CYP2E1 DB07316|N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide HSD11B1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;HSD11B1 GO:0055114| oxidation-reduction process HSD11B1;CYP2E1 32953:[DB06728 DB13857] DB06728|Aniline KLK1;ALB;CYP2E1 DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 32954:[DB06728 DB00587] DB06728|Aniline KLK1;ALB;CYP2E1 DB00587|Cinalukast CYSLTR1 common genes common pathways 32955:[DB06728 DB05939] DB06728|Aniline KLK1;ALB;CYP2E1 DB05939|MK-0354 GPER1 common genes common pathways 32956:[DB06728 DB04180] DB06728|Aniline KLK1;ALB;CYP2E1 DB04180|4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide CA2 common genes common pathways 32957:[DB06728 DB00272] DB06728|Aniline KLK1;ALB;CYP2E1 DB00272|Betazole HRH2 common genes common pathways 32958:[DB06728 DB00952] DB06728|Aniline KLK1;ALB;CYP2E1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0045471| response to ethanol CYP2E1;HTR1B GO:0055114| oxidation-reduction process MAOA;CYP2E1 GO:0042493| response to drug HTR1B;CYP2E1 32959:[DB06728 DB12662] DB06728|Aniline KLK1;ALB;CYP2E1 DB12662|Naveglitazar PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 32960:[DB06728 DB03179] DB06728|Aniline KLK1;ALB;CYP2E1 DB03179|Sinapoyl Coenzyme A COMTD1 common genes common pathways 32961:[DB06728 DB11328] DB06728|Aniline KLK1;ALB;CYP2E1 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways 32962:[DB06728 DB00019] DB06728|Aniline KLK1;ALB;CYP2E1 DB00019|Pegfilgrastim CSF3R;ELANE common genes common pathways GO:0006508| proteolysis KLK1;ELANE 32963:[DB06728 DB13615] DB06728|Aniline KLK1;ALB;CYP2E1 DB13615|Mifamurtide TLR4;NOD2 common genes common pathways 32964:[DB06728 DB00909] DB06728|Aniline KLK1;ALB;CYP2E1 DB00909|Zonisamide SCN1A;SCN2A;SCN3A;SCN4A;SCN5A;SCN9A;SCN11A;SCN1B;SCN2B;SCN3B;SCN4B;CACNA1G;CACNA1H;CACNA1I;CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA8;CA9;CA10;CA11;CA12;CA13;CA14;MAOB;MAOA;CYP3A4;AOX1;CYP2C19;UGT1A1;CYP3A5 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;UGT1A1;CYP2C19 GO:0045471| response to ethanol CYP2E1;CA3;MAOB;UGT1A1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5;CYP2C19 GO:0042493| response to drug MAOB;UGT1A1;CA9;CYP2E1;SCN11A GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;MAOB;AOX1;MAOA;CYP3A4;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1;CYP3A5;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2C19;UGT1A1;AOX1 32965:[DB06728 DB08029] DB06728|Aniline KLK1;ALB;CYP2E1 DB08029|N~2~-(biphenyl-4-ylsulfonyl)-N-hydroxy-N~2~-(2-hydroxyethyl)glycinamide MMP3 common genes common pathways GO:0006508| proteolysis MMP3;KLK1 32966:[DB06728 DB09147] DB06728|Aniline KLK1;ALB;CYP2E1 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways GO:0006898| receptor-mediated endocytosis HBA1;HBB;ALB GO:0098869| ALB;HBB;HBA1 32967:[DB06728 DB00109] DB06728|Aniline KLK1;ALB;CYP2E1 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes CYP2E1 common pathways GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0045471| response to ethanol CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;CYP2E1 GO:0010193| response to ozone CYP2E1 32968:[DB06728 DB02371] DB06728|Aniline KLK1;ALB;CYP2E1 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways GO:0006508| proteolysis C1S;KLK1 32969:[DB06728 DB02028] DB06728|Aniline KLK1;ALB;CYP2E1 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways 32970:[DB06728 DB07209] DB06728|Aniline KLK1;ALB;CYP2E1 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways GO:0042493| response to drug CYP2E1;PPARG 32971:[DB06728 DB08583] DB06728|Aniline KLK1;ALB;CYP2E1 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways 32972:[DB06728 DB00646] DB06728|Aniline KLK1;ALB;CYP2E1 DB00646|Nystatin CYP3A4;SLCO1B1;SLCO1B3 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B3;SLCO1B1;ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 32973:[DB06728 DB00222] DB06728|Aniline KLK1;ALB;CYP2E1 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0042493| response to drug ABCC8;KCNJ11;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0015721| bile acid and bile salt transport ALB;ABCB11 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 32974:[DB06728 DB08462] DB06728|Aniline KLK1;ALB;CYP2E1 DB08462|N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE SRC common genes common pathways GO:0042493| response to drug CYP2E1;SRC GO:0043066| negative regulation of apoptotic process SRC;ALB 32975:[DB06728 DB00721] DB06728|Aniline KLK1;ALB;CYP2E1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0042493| response to drug BCHE;MAOB;SLC6A3;CYP2E1 GO:0055114| oxidation-reduction process MAOA;CYP2E1;MAOB GO:0045471| response to ethanol CYP2E1;HTR3A;SLC6A3;MAOB;GRIN3A 32976:[DB06728 DB00273] DB06728|Aniline KLK1;ALB;CYP2E1 DB00273|Topiramate GABRA1;SCN1A;GRIK1;CA2;CA4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CA1;CA3;CYP2C19;CYP3A4 common genes common pathways GO:0045471| response to ethanol CA3;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0055114| oxidation-reduction process CYP2C19;CYP2E1;CYP3A4 GO:0042493| response to drug GABRG3;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 32977:[DB06728 DB14507] DB06728|Aniline KLK1;ALB;CYP2E1 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;GSK3B 32978:[DB06728 DB03932] DB06728|Aniline KLK1;ALB;CYP2E1 DB03932|LFA703 ITGAL common genes common pathways 32979:[DB06728 DB03395] DB06728|Aniline KLK1;ALB;CYP2E1 DB03395|Enalkiren REN common genes common pathways GO:0042493| response to drug CYP2E1;REN GO:0006508| proteolysis KLK1;REN 32980:[DB06728 DB04152] DB06728|Aniline KLK1;ALB;CYP2E1 DB04152|2-Amino-3-(3-Hydroxy-7,8-Dihydro-6h-Cyclohepta[D]-4-Isoxazolyl)Propionic Acid GRIA2 common genes common pathways 32981:[DB06728 DB01195] DB06728|Aniline KLK1;ALB;CYP2E1 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2D6;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP2E1 32982:[DB06728 DB11071] DB06728|Aniline KLK1;ALB;CYP2E1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;PTGS1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS2;PTGS1 32983:[DB06728 DB08191] DB06728|Aniline KLK1;ALB;CYP2E1 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways 32984:[DB06728 DB13257] DB06728|Aniline KLK1;ALB;CYP2E1 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes common pathways GO:0098869| ALB;PTGS1;CAT;PTGS2 GO:0010193| response to ozone CAT;CYP2E1 GO:0044267| cellular protein metabolic process TF;CP;ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2;MPO;CAT GO:0019373| epoxygenase P450 pathway CYP4A11;CYP2E1 GO:0002576| platelet degranulation TF;ALB GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process XDH;CYP4A11;PTGS2;SDHA;CYP2E1;TMLHE;CP;PTGS1;MPO;PCBD1;FTH1;CAT;NDUFS8;NOS2;RRM1;TPH1;P4HA1;SUOX GO:0043687| post-translational protein modification ALB;CP;TF GO:0042493| response to drug CAT;CYP2E1;PTGS2 GO:0006641| triglyceride metabolic process CYP2E1;CAT GO:0001895| retina homeostasis TF;ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 GO:0045471| response to ethanol CYP2E1;CAT 32985:[DB06728 DB05232] DB06728|Aniline KLK1;ALB;CYP2E1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways 32986:[DB06728 DB04440] DB06728|Aniline KLK1;ALB;CYP2E1 DB04440|Nebularine ADA common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;ADA GO:0042493| response to drug ADA;CYP2E1 32987:[DB06728 DB03851] DB06728|Aniline KLK1;ALB;CYP2E1 DB03851|Carbazole Butanoic Acid FABP4 common genes common pathways 32988:[DB06728 DB00056] DB06728|Aniline KLK1;ALB;CYP2E1 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0006898| receptor-mediated endocytosis FCGR2B;ALB;FCGR1A GO:0006508| proteolysis C1R;C1QB;C1QC;C1S;C1QA;KLK1 32989:[DB06728 DB08478] DB06728|Aniline KLK1;ALB;CYP2E1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug TYMS;CYP2E1 GO:0045471| response to ethanol CYP2E1;TYMS 32990:[DB06728 DB07931] DB06728|Aniline KLK1;ALB;CYP2E1 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0006805| xenobiotic metabolic process AKR1C1;CYP2E1;NR1I2 GO:0055114| oxidation-reduction process AKR1C1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;NR1I2 GO:0015721| bile acid and bile salt transport AKR1C1;ALB 32991:[DB06728 DB05950] DB06728|Aniline KLK1;ALB;CYP2E1 DB05950|Contulakin-G CACNA1B common genes common pathways 32992:[DB06728 DB04371] DB06728|Aniline KLK1;ALB;CYP2E1 DB04371|AL6528 CA2 common genes common pathways 32993:[DB06728 DB07112] DB06728|Aniline KLK1;ALB;CYP2E1 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways GO:0055114| oxidation-reduction process EGLN1;CYP2E1 32994:[DB06728 DB02479] DB06728|Aniline KLK1;ALB;CYP2E1 DB02479|(R)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide CA2 common genes common pathways 32995:[DB06728 DB01827] DB06728|Aniline KLK1;ALB;CYP2E1 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways 32996:[DB06728 DB00996] DB06728|Aniline KLK1;ALB;CYP2E1 DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0045471| response to ethanol GRIN2A;GRIN1;CYP2E1;GRIN2B;GRIN3A GO:0042493| response to drug CYP2E1;GRIN2A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0043066| negative regulation of apoptotic process ADORA1;ALB GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 32997:[DB06728 DB11219] DB06728|Aniline KLK1;ALB;CYP2E1 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways 32998:[DB06728 DB07016] DB06728|Aniline KLK1;ALB;CYP2E1 DB07016|(3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 32999:[DB06728 DB03732] DB06728|Aniline KLK1;ALB;CYP2E1 DB03732|Etheno-Nadp BST1 common genes common pathways 33000:[DB06728 DB05183] DB06728|Aniline KLK1;ALB;CYP2E1 DB05183|MLN0415 IKBKB common genes common pathways GO:0043066| negative regulation of apoptotic process IKBKB;ALB 33001:[DB06728 DB08970] DB06728|Aniline KLK1;ALB;CYP2E1 DB08970|Fluprednidene CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 33002:[DB06728 DB03382] DB06728|Aniline KLK1;ALB;CYP2E1 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;SOD1 GO:0042493| response to drug SOD1;CYP2E1 GO:0002576| platelet degranulation SOD1;ALB GO:0043066| negative regulation of apoptotic process ALB;SOD1 GO:0006508| proteolysis PREP;KLK1 GO:0045471| response to ethanol SOD1;CYP2E1 GO:0001895| retina homeostasis SOD1;ALB 33003:[DB06728 DB06637] DB06728|Aniline KLK1;ALB;CYP2E1 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes CYP2E1 common pathways GO:0008202| steroid metabolic process CYP2E1 GO:0017144| drug metabolic process CYP2E1 GO:0010193| response to ozone CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2E1 GO:0018910| benzene metabolic process CYP2E1 GO:0042493| response to drug CYP2E1 GO:0055114| oxidation-reduction process CYP2E1 GO:0010243| response to organic nitrogen CYP2E1 GO:0006641| triglyceride metabolic process CYP2E1 GO:0018885| carbon tetrachloride metabolic process CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1 GO:0045471| response to ethanol KCNC2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1 GO:0042197| halogenated hydrocarbon metabolic process CYP2E1 33004:[DB06728 DB08790] DB06728|Aniline KLK1;ALB;CYP2E1 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways 33005:[DB06728 DB07940] DB06728|Aniline KLK1;ALB;CYP2E1 DB07940|9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE BCHE common genes common pathways GO:0042493| response to drug CYP2E1;BCHE 33006:[DB06728 DB03935] DB06728|Aniline KLK1;ALB;CYP2E1 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways GO:0002576| platelet degranulation ALB;ANXA5 GO:0043066| negative regulation of apoptotic process ANXA5;ALB 33007:[DB06728 DB00722] DB06728|Aniline KLK1;ALB;CYP2E1 DB00722|Lisinopril ACE common genes common pathways GO:0006508| proteolysis ACE;KLK1 33008:[DB06728 DB01746] DB06728|Aniline KLK1;ALB;CYP2E1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways 33009:[DB06728 DB06207] DB06728|Aniline KLK1;ALB;CYP2E1 DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0008202| steroid metabolic process UGT2B7;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;ABCB4;ABCB1;ADRA1A GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 33010:[DB06728 DB08558] DB06728|Aniline KLK1;ALB;CYP2E1 DB08558|2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL lpxA;fbpC;ADRB1;LCT common genes common pathways 33011:[DB06728 DB08052] DB06728|Aniline KLK1;ALB;CYP2E1 DB08052|1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0043066| negative regulation of apoptotic process SRC;ALB GO:0042493| response to drug CYP2E1;SRC 33012:[DB06728 DB01259] DB06728|Aniline KLK1;ALB;CYP2E1 DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2C8;CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2C8;CYP2C19;CYP3A5 GO:0042493| response to drug CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2C19;CYP2E1;CYP3A4 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0043066| negative regulation of apoptotic process EGFR;ALB GO:0006805| xenobiotic metabolic process CYP2C19;CYP2C8;CYP3A5;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2C19 33013:[DB06728 DB07598] DB06728|Aniline KLK1;ALB;CYP2E1 DB07598|2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE GRIA2 common genes common pathways 33014:[DB06728 DB09031] DB06728|Aniline KLK1;ALB;CYP2E1 DB09031|Miltefosine ABCB1;PLD1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1 33015:[DB06728 DB08429] DB06728|Aniline KLK1;ALB;CYP2E1 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways GO:0006508| proteolysis KLK1;DPP4 33016:[DB06728 DB02217] DB06728|Aniline KLK1;ALB;CYP2E1 DB02217|Dpb-T NT5M common genes common pathways 33017:[DB06728 DB01406] DB06728|Aniline KLK1;ALB;CYP2E1 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP19A1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 33018:[DB06728 DB00862] DB06728|Aniline KLK1;ALB;CYP2E1 DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A5 GO:0042493| response to drug ABCB1;CYP2E1 33019:[DB06728 DB09552] DB06728|Aniline KLK1;ALB;CYP2E1 DB09552|Thonzonium ATP6V1C1 common genes common pathways 33020:[DB06728 DB03480] DB06728|Aniline KLK1;ALB;CYP2E1 DB03480|Brequinar Analog DHODH common genes common pathways GO:0042493| response to drug DHODH;CYP2E1 GO:0055114| oxidation-reduction process DHODH;CYP2E1 33021:[DB06728 DB04531] DB06728|Aniline KLK1;ALB;CYP2E1 DB04531|Benzylcysteine MGMT common genes common pathways GO:0042493| response to drug MGMT;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;MGMT GO:0045471| response to ethanol CYP2E1;MGMT 33022:[DB06728 DB01215] DB06728|Aniline KLK1;ALB;CYP2E1 DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0042493| response to drug CYP2E1;GABRG3 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 33023:[DB06728 DB00448] DB06728|Aniline KLK1;ALB;CYP2E1 DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP2C18;CYP3A4;CYP2E1;CYP1B1;CYP2D6;CYP2C8;CYP2C19;CYP1A1;CYP2C9 GO:0042493| response to drug CYP1A1;ABCB1;ABCG2;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C8;CYP2C19;CYP2C9;CYP1A1;CYP2C18;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2D6;CYP2C8;CYP2C19;CYP3A4;CYP2E1 GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP1A1;CYP2C9;CYP1B1;CYP2C19;CYP2C8;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2C18;CYP2E1;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP1B1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 GO:0046483| heterocycle metabolic process CYP1A1;CYP2D6;CYP2C19;CYP3A4;CYP2E1 33024:[DB06728 DB01181] DB06728|Aniline KLK1;ALB;CYP2E1 DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways GO:0008202| steroid metabolic process CYP2A6;CYP2E1;CYP3A4;CYP2B6;NR1I2;CYP2C9;CYP2C8;CYP2C19;CYP3A5 GO:0098869| PTGS1;ALB GO:0017144| drug metabolic process CYP2A6;CYP2E1;CYP3A4;CYP2B6;CYP2C9;CYP2C19;CYP2C8 GO:0055114| oxidation-reduction process PTGS1;CYP2C18;CYP3A4;CYP2E1;CYP2A6;CYP3A5;CYP2C19;CYP2C8;CYP2C9;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2C18;CYP2A6;CYP2E1;CYP2C19;CYP2C8;CYP2B6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19;CYP2C9 GO:0006805| xenobiotic metabolic process CYP3A5;CYP2C19;CYP2C8;CYP2C9;NR1I2;CYP2B6;PTGS1;CYP2C18;CYP2E1;CYP3A4 33025:[DB06728 DB06708] DB06728|Aniline KLK1;ALB;CYP2E1 DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2D6;CYP2E1;CYP3A4 33026:[DB06728 DB01625] DB06728|Aniline KLK1;ALB;CYP2E1 DB01625|Isopropamide CHRM3;CHRM4 common genes common pathways 33027:[DB06728 DB05035] DB06728|Aniline KLK1;ALB;CYP2E1 DB05035|Eprotirome THRA;THRB common genes common pathways 33028:[DB06728 DB00672] DB06728|Aniline KLK1;ALB;CYP2E1 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A6 GO:0008202| steroid metabolic process CYP2E1;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP2C9;CYP2C19;CYP2E1 GO:0098869| ALB;PTGS1 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9;CYP2C19 GO:0055114| oxidation-reduction process CYP2E1;PTGS1;CYP2C9;CYP2C19 GO:0042493| response to drug ABCC8;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2E1;PTGS1 33029:[DB06728 DB03782] DB06728|Aniline KLK1;ALB;CYP2E1 DB03782|N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 33030:[DB06728 DB06729] DB06728|Aniline KLK1;ALB;CYP2E1 DB06729|Sulfaphenazole CYP2C9;CYP2B6;CYP2C8;CYP2D6 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2D6;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP2E1 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2B6;CYP2C8;CYP2E1 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2C8;CYP2D6;CYP2E1 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP2B6;CYP2C9;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2D6;CYP2C8;CYP2B6;CYP2C9 33031:[DB06728 DB01684] DB06728|Aniline KLK1;ALB;CYP2E1 DB01684|1-Hydroxy-1-Thio-Glycerol PREP common genes common pathways GO:0006508| proteolysis KLK1;PREP 33032:[DB06728 DB11079] DB06728|Aniline KLK1;ALB;CYP2E1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2E1;PTGS1 GO:0042493| response to drug PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| PTGS2;PTGS1;ALB GO:0006805| xenobiotic metabolic process PTGS1;CYP2E1 33033:[DB06728 DB02300] DB06728|Aniline KLK1;ALB;CYP2E1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP24A1;MPO GO:0043066| negative regulation of apoptotic process MPO;ALB 33034:[DB06728 DB08437] DB06728|Aniline KLK1;ALB;CYP2E1 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways GO:0045471| response to ethanol RPL15;CYP2E1 33035:[DB06728 DB03137] DB06728|Aniline KLK1;ALB;CYP2E1 DB03137|8-(2,5-Dimethoxy-Benzyl)-2-Fluoro-9-Pent-9h-Purin-6-Ylamine HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 33036:[DB06728 DB08313] DB06728|Aniline KLK1;ALB;CYP2E1 DB08313|nocodazole HPGDS common genes common pathways 33037:[DB06728 DB04752] DB06728|Aniline KLK1;ALB;CYP2E1 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways 33038:[DB06728 DB12747] DB06728|Aniline KLK1;ALB;CYP2E1 DB12747|Tertomotide TERT common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;TERT 33039:[DB06728 DB13170] DB06728|Aniline KLK1;ALB;CYP2E1 DB13170|Plecanatide GUCY1A2 common genes common pathways 33040:[DB06728 DB05307] DB06728|Aniline KLK1;ALB;CYP2E1 DB05307|CHF-1512 DDC common genes common pathways 33041:[DB06728 DB01073] DB06728|Aniline KLK1;ALB;CYP2E1 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;RRM1 33042:[DB06728 DB00436] DB06728|Aniline KLK1;ALB;CYP2E1 DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways 33043:[DB06728 DB03983] DB06728|Aniline KLK1;ALB;CYP2E1 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways GO:0055114| oxidation-reduction process SUOX;CYP2E1 33044:[DB06728 DB00092] DB06728|Aniline KLK1;ALB;CYP2E1 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways GO:0006508| proteolysis C1QC;KLK1;C1QA;C1QB;C1R GO:0006898| receptor-mediated endocytosis FCGR1A;ALB;FCGR2B 33045:[DB06728 DB00953] DB06728|Aniline KLK1;ALB;CYP2E1 DB00953|Rizatriptan HTR1D;HTR1B;HTR1F;MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;CYP2E1 GO:0042493| response to drug CYP2E1;HTR1B GO:0045471| response to ethanol HTR1B;CYP2E1 33046:[DB06728 DB00777] DB06728|Aniline KLK1;ALB;CYP2E1 DB00777|Propiomazine HRH1;HTR2A;HTR2C;DRD2;DRD1;DRD4;ADRA1A;ADRA1B;ADRA1D;CHRM3;CHRM5;CHRM2;CHRM4;CHRM1 common genes common pathways GO:0045471| response to ethanol CYP2E1;DRD2 GO:0042493| response to drug HTR2C;ADRA1A;DRD2;DRD1;HTR2A;CYP2E1 33047:[DB06728 DB07317] DB06728|Aniline KLK1;ALB;CYP2E1 DB07317|(3E)-3-[(phenylamino)methylidene]dihydrofuran-2(3H)-one HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 33048:[DB06728 DB07974] DB06728|Aniline KLK1;ALB;CYP2E1 DB07974|1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE F10 common genes common pathways GO:0006508| proteolysis F10;KLK1 33049:[DB06728 DB13983] DB06728|Aniline KLK1;ALB;CYP2E1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1 33050:[DB06728 DB08383] DB06728|Aniline KLK1;ALB;CYP2E1 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways 33051:[DB06728 DB00990] DB06728|Aniline KLK1;ALB;CYP2E1 DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 33052:[DB06728 DB02602] DB06728|Aniline KLK1;ALB;CYP2E1 DB02602|AL7182 CA2 common genes common pathways 33053:[DB06728 DB02895] DB06728|Aniline KLK1;ALB;CYP2E1 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways GO:0098869| ALB;GSR GO:0055114| oxidation-reduction process CYP2E1;GSR 33054:[DB06728 DB11750] DB06728|Aniline KLK1;ALB;CYP2E1 DB11750|Clobetasol CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 33055:[DB06728 DB06766] DB06728|Aniline KLK1;ALB;CYP2E1 DB06766|Alcaftadine HRH1 common genes common pathways 33056:[DB06728 DB07279] DB06728|Aniline KLK1;ALB;CYP2E1 DB07279|N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE F2 common genes common pathways GO:0006508| proteolysis KLK1;F2 GO:0044267| cellular protein metabolic process F2;ALB 33057:[DB06728 DB02967] DB06728|Aniline KLK1;ALB;CYP2E1 DB02967|N-Ethylmaleimide CLC common genes common pathways 33058:[DB06728 DB07147] DB06728|Aniline KLK1;ALB;CYP2E1 DB07147|methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate ADAM17 common genes common pathways GO:0006508| proteolysis ADAM17;KLK1 GO:0042493| response to drug CYP2E1;ADAM17 33059:[DB06728 DB00484] DB06728|Aniline KLK1;ALB;CYP2E1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;AOX1 GO:0055114| oxidation-reduction process CYP2E1;AOX1 33060:[DB06728 DB01954] DB06728|Aniline KLK1;ALB;CYP2E1 DB01954|Rolipram PDE4D;PDE4B common genes common pathways 33061:[DB06728 DB08599] DB06728|Aniline KLK1;ALB;CYP2E1 DB08599|N-[(4-methoxyphenyl)sulfonyl]-D-alanine MMP12 common genes common pathways GO:0006508| proteolysis KLK1;MMP12 33062:[DB06728 DB05207] DB06728|Aniline KLK1;ALB;CYP2E1 DB05207|SD118 TNF;IL1R1 common genes common pathways 33063:[DB06728 DB06677] DB06728|Aniline KLK1;ALB;CYP2E1 DB06677|Clazosentan EDNRA common genes common pathways 33064:[DB06728 DB07223] DB06728|Aniline KLK1;ALB;CYP2E1 DB07223|METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE CTSB common genes common pathways GO:0006508| proteolysis CTSB;KLK1 33065:[DB06728 DB04258] DB06728|Aniline KLK1;ALB;CYP2E1 DB04258|Seocalcitol VDR common genes common pathways 33066:[DB06728 DB01188] DB06728|Aniline KLK1;ALB;CYP2E1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;CYP2E1 33067:[DB06728 DB08476] DB06728|Aniline KLK1;ALB;CYP2E1 DB08476|3-AMINO-AZACYCLOTRIDECAN-2-ONE MMP8 common genes common pathways GO:0006508| proteolysis KLK1;MMP8 33068:[DB06728 DB11737] DB06728|Aniline KLK1;ALB;CYP2E1 DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A4;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP1A2;CYP3A5 GO:0042493| response to drug CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;EGFR GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4;CYP1A2;CYP3A5 33069:[DB06728 DB11221] DB06728|Aniline KLK1;ALB;CYP2E1 DB11221|Dioxybenzone SHBG common genes common pathways 33070:[DB06728 DB06548] DB06728|Aniline KLK1;ALB;CYP2E1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2E1 33071:[DB06728 DB11098] DB06728|Aniline KLK1;ALB;CYP2E1 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways 33072:[DB06728 DB00045] DB06728|Aniline KLK1;ALB;CYP2E1 DB00045|Lyme disease vaccine (recombinant OspA) TLR2 common genes common pathways 33073:[DB06728 DB02492] DB06728|Aniline KLK1;ALB;CYP2E1 DB02492|Ghavamiol MAN2A1 common genes common pathways 33074:[DB06728 DB07993] DB06728|Aniline KLK1;ALB;CYP2E1 DB07993|N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE BACE1 common genes common pathways GO:0044267| cellular protein metabolic process BACE1;ALB GO:0006508| proteolysis BACE1;KLK1 33075:[DB06728 DB01944] DB06728|Aniline KLK1;ALB;CYP2E1 DB01944|(S)-blebbistatin MYH14 common genes common pathways 33076:[DB06728 DB09297] DB06728|Aniline KLK1;ALB;CYP2E1 DB09297|Paritaprevir CYP3A4;CYP3A5;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0015721| bile acid and bile salt transport ALB;SLCO1B1;SLCO1B3 GO:0043252| sodium-independent organic anion transport ALB;SLCO1B1;SLCO1B3 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP3A5 GO:0042493| response to drug ABCG2;ABCB1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP3A5 33077:[DB06728 DB04372] DB06728|Aniline KLK1;ALB;CYP2E1 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 33078:[DB06728 DB00905] DB06728|Aniline KLK1;ALB;CYP2E1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0055114| oxidation-reduction process AKR1C3;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGFR;ALB GO:0009267| cellular response to starvation AKR1C3;ALB GO:0008202| steroid metabolic process AKR1C3;CYP2E1 33079:[DB06728 DB00466] DB06728|Aniline KLK1;ALB;CYP2E1 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;CYP1A1 GO:0019373| epoxygenase P450 pathway CYP1A1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP1A1 GO:0042493| response to drug CYP1A1;CYP2E1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1 GO:0009267| cellular response to starvation ALB;GLUL GO:0017144| drug metabolic process CYP1A1;CYP2E1 33080:[DB06728 DB01078] DB06728|Aniline KLK1;ALB;CYP2E1 DB01078|Deslanoside ATP1A1 common genes common pathways GO:0042493| response to drug CYP2E1;ATP1A1 33081:[DB06728 DB09139] DB06728|Aniline KLK1;ALB;CYP2E1 DB09139|Technetium Tc-99m oxidronate ALB common genes ALB common pathways GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0019836| hemolysis by symbiont of host erythrocytes ALB 33082:[DB06728 DB11945] DB06728|Aniline KLK1;ALB;CYP2E1 DB11945|Avelumab CD274 common genes common pathways 33083:[DB06728 DB01786] DB06728|Aniline KLK1;ALB;CYP2E1 DB01786|D-Alanine SLC16A10 common genes common pathways 33084:[DB06728 DB04451] DB06728|Aniline KLK1;ALB;CYP2E1 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways GO:0006508| proteolysis CTSV;KLK1 GO:0009267| cellular response to starvation ALB;CTSV 33085:[DB06728 DB13946] DB06728|Aniline KLK1;ALB;CYP2E1 DB13946|Testosterone undecanoate AR;ESR1;NR3C2;CYP3A4;CYP19A1;MAOA;CYP11A1;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;SRD5A1;SRD5A2;SRD5A3;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2C9;CYP2C8;CYP2C19;CYP3A5;CYP1B1;CYP2A13;CYP2E1;CYP3A4;CYP3A7 GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0006898| receptor-mediated endocytosis ALB GO:0006641| triglyceride metabolic process SLC22A4;CYP2E1 GO:0042493| response to drug SRD5A2;CYP2E1;SRD5A1;CYP1A1;ABCG2;ABCB1 GO:0043687| post-translational protein modification ALB GO:0055114| oxidation-reduction process CYP2B6;CYP19A1;CYP1A1;CYP2C9;CYP1B1;CYP2C8;CYP2C19;CYP3A5;CYP3A7;MAOA;SRD5A3;SRD5A2;CYP11A1;CYP3A4;CYP2A13;CYP2E1;CYP3A43;SRD5A1 GO:0043066| negative regulation of apoptotic process ALB GO:0019373| epoxygenase P450 pathway CYP1B1;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP2B6;CYP2E1;CYP2A13 GO:0002576| platelet degranulation ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport SLCO1A2;SLC10A1;ALB GO:0008202| steroid metabolic process CYP1B1;CYP3A5;CYP2C19;CYP2C8;CYP1A1;CYP2C9;CYP2B6;SRD5A1;CYP3A7;CYP2E1;CYP3A4;CYP11A1;SRD5A2 GO:0043252| sodium-independent organic anion transport ALB;SLC22A8;SLCO1A2;SLC22A7 GO:0009267| cellular response to starvation ALB;SRD5A1 GO:0098869| ALB GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2B6;CYP2C8;CYP2C19;CYP2E1;CYP3A4 33086:[DB06728 DB02101] DB06728|Aniline KLK1;ALB;CYP2E1 DB02101|(S,R)-fidarestat AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;ALB GO:0055114| oxidation-reduction process AKR1B1;CYP2E1 33087:[DB06728 DB01225] DB06728|Aniline KLK1;ALB;CYP2E1 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways GO:0006508| proteolysis F10;KLK1 GO:0044267| cellular protein metabolic process SERPINC1;ALB GO:0043066| negative regulation of apoptotic process MPO;ALB GO:0055114| oxidation-reduction process CYP2E1;MPO GO:0043687| post-translational protein modification SERPINC1;ALB 33088:[DB06728 DB01020] DB06728|Aniline KLK1;ALB;CYP2E1 DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 33089:[DB06728 DB06258] DB06728|Aniline KLK1;ALB;CYP2E1 DB06258|Bimoclomol HSF1 common genes common pathways GO:0010243| response to organic nitrogen HSF1;CYP2E1 33090:[DB06728 DB01260] DB06728|Aniline KLK1;ALB;CYP2E1 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4 33091:[DB06728 DB05624] DB06728|Aniline KLK1;ALB;CYP2E1 DB05624|Teverelix GNRHR common genes common pathways 33092:[DB06728 DB02929] DB06728|Aniline KLK1;ALB;CYP2E1 DB02929|K201 ANXA5 common genes common pathways GO:0043066| negative regulation of apoptotic process ANXA5;ALB GO:0002576| platelet degranulation ANXA5;ALB 33093:[DB06728 DB04020] DB06728|Aniline KLK1;ALB;CYP2E1 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways 33094:[DB06728 DB07256] DB06728|Aniline KLK1;ALB;CYP2E1 DB07256|3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE EPHB4 common genes common pathways 33095:[DB06728 DB07245] DB06728|Aniline KLK1;ALB;CYP2E1 DB07245|6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE BACE1 common genes common pathways GO:0006508| proteolysis KLK1;BACE1 GO:0044267| cellular protein metabolic process ALB;BACE1 33096:[DB06728 DB05119] DB06728|Aniline KLK1;ALB;CYP2E1 DB05119|Rilapladib PLA2G7 common genes common pathways 33097:[DB06728 DB11770] DB06728|Aniline KLK1;ALB;CYP2E1 DB11770|Talinolol CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP2D6 GO:0008202| steroid metabolic process CYP2E1;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2E1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2D6 33098:[DB06728 DB02840] DB06728|Aniline KLK1;ALB;CYP2E1 DB02840|4-(1,3-Benzodioxol-5-Yl)-5-(5-Ethyl-2,4-Dihydroxyphenyl)-2h-Pyrazole-3-Carboxylic Acid HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis HSP90AA1;ALB 33099:[DB06728 DB07027] DB06728|Aniline KLK1;ALB;CYP2E1 DB07027|D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide F2 common genes common pathways GO:0044267| cellular protein metabolic process ALB;F2 GO:0006508| proteolysis F2;KLK1 33100:[DB06728 DB07723] DB06728|Aniline KLK1;ALB;CYP2E1 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways GO:0042493| response to drug PPARG;CYP2E1 33101:[DB06728 DB08038] DB06728|Aniline KLK1;ALB;CYP2E1 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways GO:0006508| proteolysis KLK7;KLK1 33102:[DB06728 DB04711] DB06728|Aniline KLK1;ALB;CYP2E1 DB04711|Iodipamide ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0043069| negative regulation of programmed cell death ALB GO:0051659| maintenance of mitochondrion location ALB GO:0006898| receptor-mediated endocytosis ALB GO:0001895| retina homeostasis ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0009267| cellular response to starvation ALB GO:0043252| sodium-independent organic anion transport ALB GO:0098869| ALB GO:0044267| cellular protein metabolic process ALB GO:0015721| bile acid and bile salt transport ALB 33103:[DB06728 DB03510] DB06728|Aniline KLK1;ALB;CYP2E1 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways 33104:[DB06728 DB01065] DB06728|Aniline KLK1;ALB;CYP2E1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;CYP1A1;CALR GO:0055114| oxidation-reduction process CYP1A2;EPX;CYP2E1;MPO;NQO2;CYP2C9;CYP1A1;CYP19A1;CYP1B1;CYP2C19;IDO1 GO:0002576| platelet degranulation CALM1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19;CYP1B1;CYP2C9;CYP1A1 GO:0043066| negative regulation of apoptotic process ALB;MPO GO:0043252| sodium-independent organic anion transport SLC22A8;ALB GO:0008202| steroid metabolic process CYP2E1;CYP1A2;CYP2C9;CYP1A1;CYP2C19;CYP1B1 GO:0098869| EPX;ALB GO:0017144| drug metabolic process CYP2C9;CYP1A1;CYP2C19;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2;CYP2C19;CYP1A1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2C9;CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1;NQO2;CYP2C9;CYP1B1;CYP2C19 GO:0006898| receptor-mediated endocytosis CALR;ALB 33105:[DB06728 DB04830] DB06728|Aniline KLK1;ALB;CYP2E1 DB04830|Buformin SLC22A1 common genes common pathways 33106:[DB06728 DB06681] DB06728|Aniline KLK1;ALB;CYP2E1 DB06681|Belatacept CD86;CD80 common genes common pathways 33107:[DB06728 DB04664] DB06728|Aniline KLK1;ALB;CYP2E1 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2B6 GO:0017144| drug metabolic process CYP2B6;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 GO:0006805| xenobiotic metabolic process CYP2B6;CYP2E1 33108:[DB06728 DB01535] DB06728|Aniline KLK1;ALB;CYP2E1 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRM1;CYP2E1;OPRK1 33109:[DB06728 DB04534] DB06728|Aniline KLK1;ALB;CYP2E1 DB04534|5-Nitroindazole NOS2;NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS2;NOS3;CYP2E1 33110:[DB06728 DB08480] DB06728|Aniline KLK1;ALB;CYP2E1 DB08480|4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN MAOB common genes common pathways GO:0045471| response to ethanol CYP2E1;MAOB GO:0042493| response to drug CYP2E1;MAOB GO:0055114| oxidation-reduction process MAOB;CYP2E1 33111:[DB06728 DB00280] DB06728|Aniline KLK1;ALB;CYP2E1 DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0006805| xenobiotic metabolic process CYP1A2;CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1;CYP1A2 GO:0002576| platelet degranulation ORM2;ORM1;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP3A4 33112:[DB06728 DB06897] DB06728|Aniline KLK1;ALB;CYP2E1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PLK1 33113:[DB06728 DB05150] DB06728|Aniline KLK1;ALB;CYP2E1 DB05150|CAD106 APP common genes common pathways GO:0044267| cellular protein metabolic process APP;ALB GO:0002576| platelet degranulation APP;ALB GO:0043687| post-translational protein modification APP;ALB 33114:[DB06728 DB01381] DB06728|Aniline KLK1;ALB;CYP2E1 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C9 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C9 GO:0042493| response to drug SLC6A2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2E1 33115:[DB06728 DB01208] DB06728|Aniline KLK1;ALB;CYP2E1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP1A2;CYP2E1 GO:0042493| response to drug CYP1A2;CYP2E1;ABCB1;ABCC2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP1A2 33116:[DB06728 DB01686] DB06728|Aniline KLK1;ALB;CYP2E1 DB01686|N,N-dimethylarginine NOS2;NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;NOS2;CYP2E1 33117:[DB06728 DB06899] DB06728|Aniline KLK1;ALB;CYP2E1 DB06899|N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOTHIAZIN-4-YL]ETHYL}ACETAMIDE REN common genes common pathways GO:0006508| proteolysis KLK1;REN GO:0042493| response to drug REN;CYP2E1 33118:[DB06728 DB08620] DB06728|Aniline KLK1;ALB;CYP2E1 DB08620|{(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide CHRFAM7A common genes common pathways 33119:[DB06728 DB13083] DB06728|Aniline KLK1;ALB;CYP2E1 DB13083|Talarozole CYP26A1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2E1;CYP26A1 GO:0055114| oxidation-reduction process CYP26A1;CYP2E1 33120:[DB06728 DB04287] DB06728|Aniline KLK1;ALB;CYP2E1 DB04287|(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid PLA2G2A common genes common pathways 33121:[DB06728 DB01283] DB06728|Aniline KLK1;ALB;CYP2E1 DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways GO:0006805| xenobiotic metabolic process PTGS1;CYP1A2;CYP2E1;CYP2C19;UGT1A9;CYP2C9 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1;CYP2C19 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;CYP2C9;PTGS1;CYP1A2;PTGS2;CYP2E1 GO:0042493| response to drug PTGS2;CYP1A2;CYP2E1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C9;CYP2C19 GO:0017144| drug metabolic process CYP1A2;CYP2E1;UGT1A9;CYP2C9;CYP2C19 GO:0098869| ALB;PTGS2;PTGS1 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;CYP2C9;CYP2C19 33122:[DB06728 DB08354] DB06728|Aniline KLK1;ALB;CYP2E1 DB08354|2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways 33123:[DB06728 DB01745] DB06728|Aniline KLK1;ALB;CYP2E1 DB01745|N-Alpha-(2-Naphthylsulfonyl)-N(3-Amidino-L-Phenylalaninyl)Isopipecolinic Acid Methyl Ester PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 33124:[DB06728 DB00403] DB06728|Aniline KLK1;ALB;CYP2E1 DB00403|Ceruletide CCKAR common genes common pathways 33125:[DB06728 DB07985] DB06728|Aniline KLK1;ALB;CYP2E1 DB07985|+/-METHYL 4-(AMINOIMINOMETHYL)-BETA-[3- INH (AMINOIMINO)PHENYL]BENZENE PENTANOATE PRSS1 common genes common pathways GO:0006508| proteolysis KLK1;PRSS1 33126:[DB06728 DB04150] DB06728|Aniline KLK1;ALB;CYP2E1 DB04150|Threonine Derivative PAM common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;PAM GO:0042493| response to drug PAM;CYP2E1 33127:[DB06728 DB01166] DB06728|Aniline KLK1;ALB;CYP2E1 DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PDE3A GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2;CYP2C19 GO:0042493| response to drug CYP1A2;CYP2E1;PDE3A GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP1A2;CYP3A7;CYP2C19;CYP2D6;CYP3A5 GO:0008202| steroid metabolic process CYP3A5;CYP2C19;CYP2D6;CYP1A2;CYP3A7;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2D6;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;CYP2D6;CYP1A2;CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP2C19;CYP2D6;CYP3A5;CYP1A2;CYP3A7;CYP2E1;CYP3A4 33128:[DB06728 DB04716] DB06728|Aniline KLK1;ALB;CYP2E1 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways 33129:[DB06728 DB06835] DB06728|Aniline KLK1;ALB;CYP2E1 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways GO:0006508| proteolysis CPB1;KLK1 33130:[DB06728 DB01003] DB06728|Aniline KLK1;ALB;CYP2E1 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways 33131:[DB06728 DB05311] DB06728|Aniline KLK1;ALB;CYP2E1 DB05311|Ecallantide KLKB1 common genes common pathways GO:0006508| proteolysis KLKB1;KLK1 33132:[DB06728 DB11597] DB06728|Aniline KLK1;ALB;CYP2E1 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 33133:[DB06728 DB07535] DB06728|Aniline KLK1;ALB;CYP2E1 DB07535|2-amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin-4(3H)-one BACE1 common genes common pathways GO:0006508| proteolysis BACE1;KLK1 GO:0044267| cellular protein metabolic process ALB;BACE1 33134:[DB06728 DB07033] DB06728|Aniline KLK1;ALB;CYP2E1 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways 33135:[DB06728 DB06902] DB06728|Aniline KLK1;ALB;CYP2E1 DB06902|4-(1-methyl-1-phenylethyl)phenol ESRRG common genes common pathways 33136:[DB06728 DB01241] DB06728|Aniline KLK1;ALB;CYP2E1 DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:0042493| response to drug UGT1A1;CYP1A2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;CYP3A4;CYP2C9;CYP2C8;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C8;CYP2C19;CYP2C9;CYP1A2;CYP2E1 GO:0015721| bile acid and bile salt transport ALB;SLCO1B1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;UGT1A1;CYP2C9;CYP1A2;CYP2E1;CYP3A4 GO:0043252| sodium-independent organic anion transport SLCO1B1;ALB GO:0017144| drug metabolic process CYP1A2;CYP2E1;CYP3A4;UGT1A3;UGT1A1;CYP2C9;CYP2C8;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP1A2;UGT1A1;CYP2C19 GO:0016098| monoterpenoid metabolic process CYP2C9;CYP2C19;CYP3A4;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0006805| xenobiotic metabolic process CYP2C9;CYP2C19;CYP2C8;CYP1A2;CYP3A4;CYP2E1 33137:[DB06728 DB00551] DB06728|Aniline KLK1;ALB;CYP2E1 DB00551|Acetohydroxamic acid ureC;MMP12 common genes common pathways GO:0006508| proteolysis KLK1;MMP12 33138:[DB06728 DB00656] DB06728|Aniline KLK1;ALB;CYP2E1 DB00656|Trazodone HTR2A;HTR2C;SLC6A4;HTR1A;HRH1;ADRA1A;ADRA2A;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ORM1;ABCB1 common genes common pathways GO:0006805| xenobiotic metabolic process CYP3A7;CYP2E1;CYP3A4;CYP3A5;CYP2D6 GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2D6 GO:0017144| drug metabolic process CYP2E1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A7;CYP3A4;CYP2E1;CYP3A5;CYP2D6 GO:0002576| platelet degranulation ALB;ORM1 GO:0055114| oxidation-reduction process CYP3A5;CYP2D6;CYP3A7;CYP2E1;CYP3A4 GO:0042493| response to drug HTR2C;ADRA1A;ABCB1;CYP2E1;HTR2A;SLC6A4 33139:[DB06728 DB11740] DB06728|Aniline KLK1;ALB;CYP2E1 DB11740|MK-1775 WEE1 common genes common pathways 33140:[DB06728 DB00778] DB06728|Aniline KLK1;ALB;CYP2E1 DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2B6 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;CYP2B6 GO:0017144| drug metabolic process CYP3A4;CYP2E1;CYP2B6 GO:0042493| response to drug ABCB1;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;CYP2B6 GO:0019373| epoxygenase P450 pathway CYP2B6;CYP2E1 33141:[DB06728 DB00022] DB06728|Aniline KLK1;ALB;CYP2E1 DB00022|Peginterferon alfa-2b IFNAR1;IFNAR2;CYP1A2;CYP2D6;CYP2C9 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2D6;CYP2C9;CYP1A2;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2;CYP2C9;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2E1;CYP1A2 GO:0019373| epoxygenase P450 pathway CYP2C9;CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP2E1;CYP1A2 33142:[DB06728 DB03408] DB06728|Aniline KLK1;ALB;CYP2E1 DB03408|gamma-Glutamylcysteine GSS common genes common pathways 33143:[DB06728 DB04209] DB06728|Aniline KLK1;ALB;CYP2E1 DB04209|Dequalinium XIAP;CNGA1;KCNMA1 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;XIAP 33144:[DB06728 DB01830] DB06728|Aniline KLK1;ALB;CYP2E1 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways GO:0042493| response to drug LCK;CYP2E1 33145:[DB06728 DB11475] DB06728|Aniline KLK1;ALB;CYP2E1 DB11475|Tylosin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP2E1;CYP3A4 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 33146:[DB06728 DB08933] DB06728|Aniline KLK1;ALB;CYP2E1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP3A4;CYP2C19 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP3A4;CYP2E1;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2C19;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2E1 GO:0017144| drug metabolic process CYP2C19;CYP3A4;CYP2E1 33147:[DB06728 DB04424] DB06728|Aniline KLK1;ALB;CYP2E1 DB04424|RPR128515 PRSS1 common genes common pathways GO:0006508| proteolysis PRSS1;KLK1 33148:[DB06728 DB05465] DB06728|Aniline KLK1;ALB;CYP2E1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0010243| response to organic nitrogen FLT3;CYP2E1 33149:[DB06728 DB11632] DB06728|Aniline KLK1;ALB;CYP2E1 DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes common pathways GO:0016098| monoterpenoid metabolic process CYP2E1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0006805| xenobiotic metabolic process CYP2C8;CYP2C19;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C8;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP2C19;CYP2C8 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19;CYP2C8 GO:0042493| response to drug CYP2E1;COMT GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;CYP2C8 33150:[DB06728 DB07376] DB06728|Aniline KLK1;ALB;CYP2E1 DB07376|5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID) F2;F7 common genes common pathways GO:0006508| proteolysis KLK1;F2;F7 GO:0044267| cellular protein metabolic process ALB;F2 33151:[DB06728 DB02398] DB06728|Aniline KLK1;ALB;CYP2E1 DB02398|6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0006508| proteolysis KLK1;PLAU 33152:[DB06728 DB00181] DB06728|Aniline KLK1;ALB;CYP2E1 DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways GO:0043252| sodium-independent organic anion transport ALB;SLC22A8 33153:[DB06728 DB02676] DB06728|Aniline KLK1;ALB;CYP2E1 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways 33154:[DB06728 DB05064] DB06728|Aniline KLK1;ALB;CYP2E1 DB05064|INCB13739 HSD11B1 common genes common pathways GO:0008202| steroid metabolic process HSD11B1;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;HSD11B1 33155:[DB06728 DB02555] DB06728|Aniline KLK1;ALB;CYP2E1 DB02555|SP4160 IL2 common genes common pathways GO:0043066| negative regulation of apoptotic process IL2;ALB GO:0045471| response to ethanol CYP2E1;IL2 33156:[DB06728 DB08891] DB06728|Aniline KLK1;ALB;CYP2E1 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways 33157:[DB06728 DB08618] DB06728|Aniline KLK1;ALB;CYP2E1 DB08618|3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER IGHG2 common genes common pathways GO:0006508| proteolysis IGHG2;KLK1 33158:[DB06728 DB11674] DB06728|Aniline KLK1;ALB;CYP2E1 DB11674|Equol ESR2;SHBG common genes common pathways 33159:[DB06728 DB01884] DB06728|Aniline KLK1;ALB;CYP2E1 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways GO:0006508| proteolysis DPP4;KLK1 33160:[DB06728 DB07913] DB06728|Aniline KLK1;ALB;CYP2E1 DB07913|HOMOPHENYLALANINYLMETHANE CTSF common genes common pathways GO:0006508| proteolysis CTSF;KLK1 33161:[DB06728 DB04677] DB06728|Aniline KLK1;ALB;CYP2E1 DB04677|N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE MAOB common genes common pathways GO:0045471| response to ethanol MAOB;CYP2E1 GO:0055114| oxidation-reduction process MAOB;CYP2E1 GO:0042493| response to drug MAOB;CYP2E1 33162:[DB06728 DB01060] DB06728|Aniline KLK1;ALB;CYP2E1 DB01060|Amoxicillin CYP2C19;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006805| xenobiotic metabolic process CYP2C19;CYP2E1 GO:0016098| monoterpenoid metabolic process CYP2C19;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19 GO:0017144| drug metabolic process CYP2E1;CYP2C19 GO:0043252| sodium-independent organic anion transport SLC22A6;ALB GO:0008202| steroid metabolic process CYP2E1;CYP2C19 GO:0019373| epoxygenase P450 pathway CYP2E1;CYP2C19 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19 33163:[DB06728 DB06160] DB06728|Aniline KLK1;ALB;CYP2E1 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0019373| epoxygenase P450 pathway CYP2E1;CYP1A2 GO:0042493| response to drug CYP2E1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP1A2 GO:0016098| monoterpenoid metabolic process CYP1A2;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2E1 GO:0006805| xenobiotic metabolic process CYP1A2;CYP2E1 33164:[DB06728 DB04079] DB06728|Aniline KLK1;ALB;CYP2E1 DB04079|Heptane-1,2,3-Triol RHO common genes common pathways 33165:[DB06728 DB03087] DB06728|Aniline KLK1;ALB;CYP2E1 DB03087|2-(Sec-Butyl)Thiazole LCN9 common genes common pathways 33166:[DB06728 DB04839] DB06728|Aniline KLK1;ALB;CYP2E1 DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2E1;CYP3A4;CYP19A1 GO:0044267| cellular protein metabolic process ALB;KLK3 GO:0017144| drug metabolic process CYP3A4;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1 GO:0006508| proteolysis KLK1;KLK3 GO:0006805| xenobiotic metabolic process CYP2E1;CYP3A4 GO:0016098| monoterpenoid metabolic process CYP3A4;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP3A4 33167:[DB06728 DB08855] DB06728|Aniline KLK1;ALB;CYP2E1 DB08855|Leukotriene C4 CYSLTR1;CYSLTR2;ABCC1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC1;CYP2E1 GO:0015721| bile acid and bile salt transport SLCO1B1;SLCO1B3;ALB GO:0043252| sodium-independent organic anion transport ALB;SLCO1B3;SLCO1B1 33168:[DB06728 DB03881] DB06728|Aniline KLK1;ALB;CYP2E1 DB03881|MT-Immucillin-H PNP common genes common pathways GO:0042493| response to drug CYP2E1;PNP 33169:[DB06728 DB01276] DB06728|Aniline KLK1;ALB;CYP2E1 DB01276|Exenatide GLP1R;ALB common genes ALB common pathways GO:0019836| hemolysis by symbiont of host erythrocytes ALB GO:0006898| receptor-mediated endocytosis ALB GO:0051659| maintenance of mitochondrion location ALB GO:0043069| negative regulation of programmed cell death ALB GO:0034375| high-density lipoprotein particle remodeling ALB GO:0001895| retina homeostasis ALB GO:0043066| negative regulation of apoptotic process ALB GO:0002576| platelet degranulation ALB GO:0043687| post-translational protein modification ALB GO:0098869| ALB GO:0043252| sodium-independent organic anion transport ALB GO:0009267| cellular response to starvation ALB GO:0015721| bile acid and bile salt transport ALB GO:0044267| cellular protein metabolic process ALB 33170:[DB06728 DB14040] DB06728|Aniline KLK1;ALB;CYP2E1 DB14040|Eptinezumab CALCA;CALCB common genes common pathways 33171:[DB06728 DB01949] DB06728|Aniline KLK1;ALB;CYP2E1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process MMP9;ALB GO:0006508| proteolysis MMP9;KLK1 33172:[DB06728 DB05217] DB06728|Aniline KLK1;ALB;CYP2E1 DB05217|GMX1777 NAMPT common genes common pathways 33173:[DB06728 DB07601] DB06728|Aniline KLK1;ALB;CYP2E1 DB07601|4-chloro-6-{5-[(2-morpholin-4-ylethyl)amino]-1,2-benzisoxazol-3-yl}benzene-1,3-diol HSP90AA1 common genes common pathways GO:0006898| receptor-mediated endocytosis ALB;HSP90AA1 33174:[DB06728 DB03632] DB06728|Aniline KLK1;ALB;CYP2E1 DB03632|Argifin CHIT1 common genes common pathways 33175:[DB05630 DB07543] DB05630|Sodium stibogluconate TOP1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways 33176:[DB05630 DB11730] DB05630|Sodium stibogluconate TOP1 DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0007623| circadian rhythm CDK4;TOP1 GO:0042493| response to drug TOP1;CDK4 GO:0016310| phosphorylation CDK4;TOP1;CDK6 33177:[DB05630 DB00413] DB05630|Sodium stibogluconate TOP1 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation TOP1;HTR2B GO:0042493| response to drug DRD1;HTR2A;TOP1;HTR2B;HTR2C;HTR1B;DRD2;DRD3 GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 GO:0048511| rhythmic process TOP1;DRD4 33178:[DB05630 DB01224] DB05630|Sodium stibogluconate TOP1 DB01224|Quetiapine HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP3A4;CYP2C19;CYP2D6;ABCB1 common genes common pathways GO:0048511| rhythmic process DRD4;TOP1 GO:0042493| response to drug HTR2C;DRD2;ADRA1A;ABCB1;HTR1B;DRD3;DRD1;HTR2A;TOP1 GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0007623| circadian rhythm TOP1;HTR7 GO:0016032| viral reproduction HTR2A;TOP1 33179:[DB05630 DB06605] DB05630|Sodium stibogluconate TOP1 DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;ABCB1;ABCG2 33180:[DB05630 DB01179] DB05630|Sodium stibogluconate TOP1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0048511| rhythmic process TOP2A;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP1 GO:0040016| embryonic cleavage TOP1;TOP2A 33181:[DB05630 DB05127] DB05630|Sodium stibogluconate TOP1 DB05127|ANA971 TLR7 common genes common pathways 33182:[DB05630 DB01148] DB05630|Sodium stibogluconate TOP1 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways 33183:[DB05630 DB01594] DB05630|Sodium stibogluconate TOP1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;TOP1 33184:[DB05630 DB00645] DB05630|Sodium stibogluconate TOP1 DB00645|Dyclonine SCN10A common genes common pathways 33185:[DB05630 DB06725] DB05630|Sodium stibogluconate TOP1 DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 33186:[DB05630 DB04863] DB05630|Sodium stibogluconate TOP1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction TOP1;ITGB3 33187:[DB05630 DB00232] DB05630|Sodium stibogluconate TOP1 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways 33188:[DB05630 DB01580] DB05630|Sodium stibogluconate TOP1 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways 33189:[DB05630 DB00838] DB05630|Sodium stibogluconate TOP1 DB00838|Clocortolone NR3C1 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 33190:[DB05630 DB00196] DB05630|Sodium stibogluconate TOP1 DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33191:[DB05630 DB02789] DB05630|Sodium stibogluconate TOP1 DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways 33192:[DB05630 DB08911] DB05630|Sodium stibogluconate TOP1 DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0016310| phosphorylation MAP2K1;MAP2K2;TOP1 33193:[DB05630 DB00087] DB05630|Sodium stibogluconate TOP1 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction TOP1;FCGR2B 33194:[DB05630 DB01415] DB05630|Sodium stibogluconate TOP1 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 33195:[DB05630 DB06803] DB05630|Sodium stibogluconate TOP1 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33196:[DB05630 DB00175] DB05630|Sodium stibogluconate TOP1 DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC2;ABCG2;ABCB1;TOP1 33197:[DB05630 DB00940] DB05630|Sodium stibogluconate TOP1 DB00940|Methantheline CHRM1;HRH2 common genes common pathways 33198:[DB05630 DB09422] DB05630|Sodium stibogluconate TOP1 DB09422|Soybean oil PPARA common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0048511| rhythmic process PPARA;TOP1 33199:[DB05630 DB00098] DB05630|Sodium stibogluconate TOP1 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways GO:0016032| viral reproduction ITGB3;CD86;FCGR2B;ITGAV;ITGB1;CD4;TOP1 33200:[DB05630 DB00816] DB05630|Sodium stibogluconate TOP1 DB00816|Orciprenaline ADRB2 common genes common pathways 33201:[DB05630 DB00543] DB05630|Sodium stibogluconate TOP1 DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0048511| rhythmic process DRD4;TOP1 GO:0007623| circadian rhythm SLC6A4;TOP1;HTR7 GO:0042493| response to drug SLC6A2;DRD3;DRD2;ADRA1A;HTR1B;HTR2C;HTR2B;SLC6A3;TOP1;HTR2A;SLC6A4;DRD1;GABRG3 GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 33202:[DB05630 DB00936] DB05630|Sodium stibogluconate TOP1 DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 33203:[DB05630 DB01165] DB05630|Sodium stibogluconate TOP1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0007059| chromosome segregation TOP2A;TOP1 GO:0016925| protein sumoylation TOP2A;TOP1 GO:0042493| response to drug CYP1A2;TOP1;ABCC1;ABCC2 GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP1 33204:[DB05630 DB00671] DB05630|Sodium stibogluconate TOP1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 33205:[DB05630 DB03410] DB05630|Sodium stibogluconate TOP1 DB03410|4-hydroxycoumarin CYP3A4 common genes common pathways 33206:[DB05630 DB06685] DB05630|Sodium stibogluconate TOP1 DB06685|Laquinimod CYP3A4 common genes common pathways 33207:[DB05630 DB01618] DB05630|Sodium stibogluconate TOP1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0042493| response to drug DRD2;TOP1;HTR2A GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0016032| viral reproduction HTR2A;TOP1 33208:[DB05630 DB08894] DB05630|Sodium stibogluconate TOP1 DB08894|Peginesatide EPOR common genes common pathways 33209:[DB05630 DB05111] DB05630|Sodium stibogluconate TOP1 DB05111|Fontolizumab IFNG common genes common pathways 33210:[DB05630 DB01023] DB05630|Sodium stibogluconate TOP1 DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33211:[DB05630 DB00617] DB05630|Sodium stibogluconate TOP1 DB00617|Paramethadione CACNA1I;CYP2E1;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 33212:[DB05630 DB01029] DB05630|Sodium stibogluconate TOP1 DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;JUN GO:0007623| circadian rhythm JUN;TOP1 33213:[DB05630 DB01436] DB05630|Sodium stibogluconate TOP1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0016032| viral reproduction TOP1;RXRA 33214:[DB05630 DB00681] DB05630|Sodium stibogluconate TOP1 DB00681|Amphotericin B CYP3A4 common genes common pathways 33215:[DB05630 DB00866] DB05630|Sodium stibogluconate TOP1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways 33216:[DB05630 DB06233] DB05630|Sodium stibogluconate TOP1 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0016310| phosphorylation MTOR;TOP1 GO:0018105| peptidyl-serine phosphorylation TOP1;MTOR 33217:[DB05630 DB00843] DB05630|Sodium stibogluconate TOP1 DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;HTR2A GO:0006260| DNA replication ACHE;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 33218:[DB05630 DB00987] DB05630|Sodium stibogluconate TOP1 DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0016310| phosphorylation TOP1;DCK GO:0006260| DNA replication POLB;TOP1 33219:[DB05630 DB11785] DB05630|Sodium stibogluconate TOP1 DB11785|Anisodamine CYP2D6 common genes common pathways 33220:[DB05630 DB05258] DB05630|Sodium stibogluconate TOP1 DB05258|Natural alpha interferon IFNAR1 common genes common pathways 33221:[DB05630 DB09160] DB05630|Sodium stibogluconate TOP1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33222:[DB05630 DB12872] DB05630|Sodium stibogluconate TOP1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0042493| response to drug TOP1;COL1A1 33223:[DB05630 DB00135] DB05630|Sodium stibogluconate TOP1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0042493| response to drug TH;TOP1 33224:[DB05630 DB08877] DB05630|Sodium stibogluconate TOP1 DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0016310| phosphorylation JAK1;JAK2;TOP1 33225:[DB05630 DB11641] DB05630|Sodium stibogluconate TOP1 DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33226:[DB05630 DB00654] DB05630|Sodium stibogluconate TOP1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways 33227:[DB05630 DB01211] DB05630|Sodium stibogluconate TOP1 DB01211|Clarithromycin rplJ;KCNH2;SLCO1B1;SLCO1B3;CYP3A4;CYP3A5;CYP2C19;CYP3A7;SLC22A7;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33228:[DB05630 DB00292] DB05630|Sodium stibogluconate TOP1 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 33229:[DB05630 DB01218] DB05630|Sodium stibogluconate TOP1 DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways 33230:[DB05630 DB01099] DB05630|Sodium stibogluconate TOP1 DB01099|Flucytosine DNMT1 common genes common pathways 33231:[DB05630 DB01204] DB05630|Sodium stibogluconate TOP1 DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP2A;TOP1 GO:0042493| response to drug ABCC1;ABCG2;ABCB1;CYP2E1;TOP1 GO:0048511| rhythmic process TOP1;TOP2A 33232:[DB05630 DB06267] DB05630|Sodium stibogluconate TOP1 DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways 33233:[DB05630 DB06660] DB05630|Sodium stibogluconate TOP1 DB06660|Saredutant TACR2 common genes common pathways 33234:[DB05630 DB09090] DB05630|Sodium stibogluconate TOP1 DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways 33235:[DB05630 DB12836] DB05630|Sodium stibogluconate TOP1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33236:[DB05630 DB00139] DB05630|Sodium stibogluconate TOP1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0042493| response to drug OXCT1;TOP1 33237:[DB05630 DB06156] DB05630|Sodium stibogluconate TOP1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug TOP1;SLC6A4;SLC6A2;SLC6A3 GO:0007623| circadian rhythm TOP1;SLC6A4 33238:[DB05630 DB01430] DB05630|Sodium stibogluconate TOP1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 33239:[DB05630 DB06701] DB05630|Sodium stibogluconate TOP1 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug TOP1;SLC6A4;SLC6A2;SLC6A3 GO:0007623| circadian rhythm TOP1;SLC6A4 33240:[DB05630 DB00736] DB05630|Sodium stibogluconate TOP1 DB00736|Esomeprazole ATP4A;CYP2C19;CYP3A4 common genes common pathways 33241:[DB05630 DB01198] DB05630|Sodium stibogluconate TOP1 DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0042493| response to drug TSPO;CYP2E1;TOP1 33242:[DB05630 DB04017] DB05630|Sodium stibogluconate TOP1 DB04017|Clorgiline MAOA common genes common pathways 33243:[DB05630 DB00854] DB05630|Sodium stibogluconate TOP1 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways 33244:[DB05630 DB00493] DB05630|Sodium stibogluconate TOP1 DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 33245:[DB05630 DB00623] DB05630|Sodium stibogluconate TOP1 DB00623|Fluphenazine DRD2;DRD1;CALM1;AR;HTR2A;HTR2C;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug ABCB1;DRD2;HTR2C;DRD1;TOP1;CYP2E1;HTR2A 33246:[DB05630 DB14050] DB05630|Sodium stibogluconate TOP1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0042493| response to drug TOP1;TRPA1 33247:[DB05630 DB01245] DB05630|Sodium stibogluconate TOP1 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0006260| DNA replication ACHE;TOP1 GO:0042493| response to drug BCHE;TOP1 33248:[DB05630 DB00622] DB05630|Sodium stibogluconate TOP1 DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A;CYP2E1;TOP1 33249:[DB05630 DB05785] DB05630|Sodium stibogluconate TOP1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0042493| response to drug TOP1;JUN GO:0007623| circadian rhythm JUN;TOP1 33250:[DB05630 DB00119] DB05630|Sodium stibogluconate TOP1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0012501| programmed cell death TOP1;PKM GO:0042493| response to drug TOP1;ABAT GO:0016310| phosphorylation PKLR;PKM;TOP1 33251:[DB05630 DB11201] DB05630|Sodium stibogluconate TOP1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 33252:[DB05630 DB00370] DB05630|Sodium stibogluconate TOP1 DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4;HTR7 GO:0032922| circadian regulation of gene expression DRD2;DRD3;TOP1 GO:0042493| response to drug DRD3;SLC6A2;SLC6A3;HTR2C;HTR2B;DRD2;ADRA1A;HTR2A;TOP1;CYP1A2;DRD1;SLC6A4 GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 33253:[DB05630 DB01118] DB05630|Sodium stibogluconate TOP1 DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;ABCB1;CYP1A1;PPARG GO:0048511| rhythmic process TOP1;PPARG 33254:[DB05630 DB00392] DB05630|Sodium stibogluconate TOP1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0042493| response to drug TOP1;BCHE 33255:[DB05630 DB00775] DB05630|Sodium stibogluconate TOP1 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction TOP1;ITGB3 33256:[DB05630 DB00768] DB05630|Sodium stibogluconate TOP1 DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways 33257:[DB05630 DB00483] DB05630|Sodium stibogluconate TOP1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0006260| DNA replication TOP1;ACHE 33258:[DB05630 DB00300] DB05630|Sodium stibogluconate TOP1 DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC2;AK4;TOP1;ABCC4;NME1 GO:0016310| phosphorylation NME2;NME1;TOP1;AK4;AK2 33259:[DB05630 DB00416] DB05630|Sodium stibogluconate TOP1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways 33260:[DB05630 DB01036] DB05630|Sodium stibogluconate TOP1 DB01036|Tolterodine CHRM3;CHRM2;CHRM5;CHRM1;CHRM4;CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways 33261:[DB05630 DB01914] DB05630|Sodium stibogluconate TOP1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0016310| phosphorylation HK1;GCK;TOP1 33262:[DB05630 DB06506] DB05630|Sodium stibogluconate TOP1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways 33263:[DB05630 DB00063] DB05630|Sodium stibogluconate TOP1 DB00063|Eptifibatide ITGB3 common genes common pathways GO:0016032| viral reproduction ITGB3;TOP1 33264:[DB05630 DB00960] DB05630|Sodium stibogluconate TOP1 DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0042493| response to drug TOP1;HTR1B 33265:[DB05630 DB14568] DB05630|Sodium stibogluconate TOP1 DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33266:[DB05630 DB09273] DB05630|Sodium stibogluconate TOP1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;ADORA2A 33267:[DB05630 DB05308] DB05630|Sodium stibogluconate TOP1 DB05308|ANX-510 TYMS common genes common pathways GO:0007623| circadian rhythm TOP1;TYMS GO:0042493| response to drug TYMS;TOP1 33268:[DB05630 DB00290] DB05630|Sodium stibogluconate TOP1 DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0042493| response to drug TOP1;BLMH GO:0006260| DNA replication LIG1;TOP1;LIG3 33269:[DB05630 DB00732] DB05630|Sodium stibogluconate TOP1 DB00732|Atracurium besylate CHRNA2 common genes common pathways 33270:[DB05630 DB14597] DB05630|Sodium stibogluconate TOP1 DB14597|Lanadelumab KLKB1 common genes common pathways 33271:[DB05630 DB00945] DB05630|Sodium stibogluconate TOP1 DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0012501| programmed cell death TOP1;TP53 GO:0048511| rhythmic process PRKAA1;NFKB2;PRKAA2;TP53;TOP1 GO:0042493| response to drug ABCB1;TP53;PTGS2;TOP1 GO:0016310| phosphorylation TOP1;IKBKB;PRKAA2;RPS6KA3;PRKAA1 GO:0016032| viral reproduction NFKBIA;TP53;TOP1 GO:0018105| peptidyl-serine phosphorylation IKBKB;TOP1;RPS6KA3 33272:[DB05630 DB06739] DB05630|Sodium stibogluconate TOP1 DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0042493| response to drug TOP1;TBXA2R 33273:[DB05630 DB00296] DB05630|Sodium stibogluconate TOP1 DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33274:[DB05630 DB07670] DB05630|Sodium stibogluconate TOP1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways 33275:[DB05630 DB01079] DB05630|Sodium stibogluconate TOP1 DB01079|Tegaserod HTR4;HTR2B;HTR2C;HTR2A;CYP1A2;CYP2C8;CYP2D6;CYP2E1;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A4;CYP1A2;TOP1;CYP2E1;HTR2A;HTR2C;HTR2B GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 33276:[DB05630 DB01087] DB05630|Sodium stibogluconate TOP1 DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;CYP1A1;ABCB1 GO:0016032| viral reproduction TOP1;KRT7 33277:[DB05630 DB06247] DB05630|Sodium stibogluconate TOP1 DB06247|CX516 GRIA1 common genes common pathways 33278:[DB05630 DB11753] DB05630|Sodium stibogluconate TOP1 DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;ABCB1 33279:[DB05630 DB01124] DB05630|Sodium stibogluconate TOP1 DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0042493| response to drug TOP1;ABCC8 33280:[DB05630 DB00997] DB05630|Sodium stibogluconate TOP1 DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes common pathways GO:0007059| chromosome segregation TOP1;TOP2A GO:0007623| circadian rhythm TOP1;NOS2 GO:0042493| response to drug ABCC6;ABCC1;ABCC2;ABCG2;POR;ABCB1;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP1;TOP2A 33281:[DB05630 DB00266] DB05630|Sodium stibogluconate TOP1 DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways 33282:[DB05630 DB13783] DB05630|Sodium stibogluconate TOP1 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways GO:0042493| response to drug TOP1;PTGS2;ABCC1 33283:[DB05630 DB00800] DB05630|Sodium stibogluconate TOP1 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0042493| response to drug DRD1;TOP1;ADRA1A 33284:[DB05630 DB05676] DB05630|Sodium stibogluconate TOP1 DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways 33285:[DB05630 DB06694] DB05630|Sodium stibogluconate TOP1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 33286:[DB05630 DB11587] DB05630|Sodium stibogluconate TOP1 DB11587|Etafedrine ADRB2 common genes common pathways 33287:[DB05630 DB12555] DB05630|Sodium stibogluconate TOP1 DB12555|Nelotanserin HTR2A common genes common pathways GO:0042493| response to drug TOP1;HTR2A GO:0016032| viral reproduction HTR2A;TOP1 33288:[DB05630 DB06469] DB05630|Sodium stibogluconate TOP1 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0016310| phosphorylation FLT3;TOP1 33289:[DB05630 DB06737] DB05630|Sodium stibogluconate TOP1 DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways 33290:[DB05630 DB14583] DB05630|Sodium stibogluconate TOP1 DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 33291:[DB05630 DB08867] DB05630|Sodium stibogluconate TOP1 DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug TOP1;CYP1A2 33292:[DB05630 DB01251] DB05630|Sodium stibogluconate TOP1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0042493| response to drug ABCC8;TOP1 33293:[DB05630 DB09235] DB05630|Sodium stibogluconate TOP1 DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways 33294:[DB05630 DB04725] DB05630|Sodium stibogluconate TOP1 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 33295:[DB05630 DB00153] DB05630|Sodium stibogluconate TOP1 DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways 33296:[DB05630 DB00358] DB05630|Sodium stibogluconate TOP1 DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;BCHE;ADORA2A GO:0006260| DNA replication TOP1;ACHE 33297:[DB05630 DB00770] DB05630|Sodium stibogluconate TOP1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0042493| response to drug ABCC4;TOP1 33298:[DB05630 DB05956] DB05630|Sodium stibogluconate TOP1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0016032| viral reproduction TOP1;RXRA 33299:[DB05630 DB09256] DB05630|Sodium stibogluconate TOP1 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0042493| response to drug TYMS;CYP2E1;TOP1;CYP1A2 GO:0007623| circadian rhythm TOP1;TYMS 33300:[DB05630 DB09229] DB05630|Sodium stibogluconate TOP1 DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0042493| response to drug ADRA1A;TOP1 33301:[DB05630 DB09078] DB05630|Sodium stibogluconate TOP1 DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0016032| viral reproduction TOP1;KDR GO:0016310| phosphorylation KIT;FGFR2;TOP1;FLT1;FGFR1;KDR;FGFR4;FGFR3;FLT4 GO:0042493| response to drug TOP1;CYP1A2;ABCG2;ABCB1 33302:[DB05630 DB04974] DB05630|Sodium stibogluconate TOP1 DB04974|AP1903 MTOR common genes common pathways GO:0018105| peptidyl-serine phosphorylation MTOR;TOP1 GO:0016310| phosphorylation TOP1;MTOR 33303:[DB05630 DB00417] DB05630|Sodium stibogluconate TOP1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 33304:[DB05630 DB11691] DB05630|Sodium stibogluconate TOP1 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways 33305:[DB05630 DB06311] DB05630|Sodium stibogluconate TOP1 DB06311|Darapladib PLA2G4A common genes common pathways 33306:[DB05630 DB14515] DB05630|Sodium stibogluconate TOP1 DB14515|Magnesium lactate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 33307:[DB05630 DB00701] DB05630|Sodium stibogluconate TOP1 DB00701|Amprenavir pol;CYP3A4;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A5;ABCB1;ABCC1;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;TOP1 33308:[DB05630 DB00738] DB05630|Sodium stibogluconate TOP1 DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0042493| response to drug TOP1;CYP1A1 33309:[DB05630 DB00882] DB05630|Sodium stibogluconate TOP1 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;TOP1;CYP1A2;CYP2E1 GO:0006338| chromatin remodeling ESR1;TOP1 33310:[DB05630 DB09224] DB05630|Sodium stibogluconate TOP1 DB09224|Melperone DRD2;CYP2D6 common genes common pathways GO:0042493| response to drug DRD2;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 33311:[DB05630 DB01248] DB05630|Sodium stibogluconate TOP1 DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0018105| peptidyl-serine phosphorylation BCL2;TOP1 GO:0042493| response to drug TOP1;BCL2;ABCC1;ABCB1;ABCC2;ABCG2 33312:[DB05630 DB00172] DB05630|Sodium stibogluconate TOP1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0012501| programmed cell death PPIF;TOP1 GO:0016032| viral reproduction TOP1;PPIA 33313:[DB05630 DB00269] DB05630|Sodium stibogluconate TOP1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 33314:[DB05630 DB00497] DB05630|Sodium stibogluconate TOP1 DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways 33315:[DB05630 DB12128] DB05630|Sodium stibogluconate TOP1 DB12128|Ulimorelin GHSR common genes common pathways 33316:[DB05630 DB05420] DB05630|Sodium stibogluconate TOP1 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0006260| DNA replication TOP1;RRM1 33317:[DB05630 DB08903] DB05630|Sodium stibogluconate TOP1 DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways 33318:[DB05630 DB08931] DB05630|Sodium stibogluconate TOP1 DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;CYP1A1;TOP1 33319:[DB05630 DB01058] DB05630|Sodium stibogluconate TOP1 DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33320:[DB05630 DB08735] DB05630|Sodium stibogluconate TOP1 DB08735|R,S-Warfarin alcohol ALB common genes common pathways 33321:[DB05630 DB00332] DB05630|Sodium stibogluconate TOP1 DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways 33322:[DB05630 DB05025] DB05630|Sodium stibogluconate TOP1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0042493| response to drug SOD1;TOP1 33323:[DB05630 DB06824] DB05630|Sodium stibogluconate TOP1 DB06824|Triethylenetetramine GPC1 common genes common pathways 33324:[DB05630 DB06780] DB05630|Sodium stibogluconate TOP1 DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways 33325:[DB05630 DB00991] DB05630|Sodium stibogluconate TOP1 DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 33326:[DB05630 DB02750] DB05630|Sodium stibogluconate TOP1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 33327:[DB05630 DB11638] DB05630|Sodium stibogluconate TOP1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0012501| programmed cell death TOP1;PKM GO:0048511| rhythmic process HNRNPD;TOP1;SFPQ;DDX5 GO:0042493| response to drug LDHA;LGALS1;HNRNPD;SRP14;TOP1 GO:0016310| phosphorylation TOP1;PKM;PGK1 GO:0016032| viral reproduction HNRNPK;PPIA;NPM1;HSPA8;ZYX;TOP1;VIM 33328:[DB05630 DB01161] DB05630|Sodium stibogluconate TOP1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0042493| response to drug TOP1;BCHE;SLC6A3 33329:[DB05630 DB06216] DB05630|Sodium stibogluconate TOP1 DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0007623| circadian rhythm TOP1;HTR7 GO:0042493| response to drug DRD3;HTR2B;HTR2C;ADRA1A;DRD2;HTR1B;HTR2A;TOP1;CYP1A2;DRD1 GO:0032922| circadian regulation of gene expression DRD2;DRD3;TOP1 GO:0048511| rhythmic process TOP1;DRD4 GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation HTR2B;TOP1 33330:[DB05630 DB07374] DB05630|Sodium stibogluconate TOP1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways 33331:[DB05630 DB14637] DB05630|Sodium stibogluconate TOP1 DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways 33332:[DB05630 DB00228] DB05630|Sodium stibogluconate TOP1 DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0042493| response to drug GABRG3;TOP1;CYP2E1 33333:[DB05630 DB00663] DB05630|Sodium stibogluconate TOP1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 33334:[DB05630 DB00801] DB05630|Sodium stibogluconate TOP1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;TOP1 33335:[DB05630 DB01282] DB05630|Sodium stibogluconate TOP1 DB01282|Carbetocin OXTR common genes common pathways GO:0042493| response to drug OXTR;TOP1 33336:[DB05630 DB00477] DB05630|Sodium stibogluconate TOP1 DB00477|Chlorpromazine DRD2;DRD1;HTR1A;HTR2A;ADRA1A;ADRA1B;HRH1;KCNH2;DRD1;DRD5;DRD3;DRD4;DRD5;HTR2C;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM3;SMPD1;CALM1;ORM1;ORM2;HTR6;HTR7;HRH4;CYP2D6;CYP1A2;CYP2E1;CYP3A4;BCHE;ALB;ABCB1;ABCB11 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0016310| phosphorylation TOP1;HTR2B GO:0032922| circadian regulation of gene expression TOP1;DRD3;DRD2 GO:0042493| response to drug DRD2;ADRA1A;ABCB1;HTR2C;HTR2B;SMPD1;BCHE;DRD3;DRD1;TOP1;CYP1A2;HTR2A;CYP2E1 GO:0007623| circadian rhythm HTR7;TOP1 GO:0048511| rhythmic process DRD4;TOP1 33337:[DB05630 DB00226] DB05630|Sodium stibogluconate TOP1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0042493| response to drug TOP1;SLC6A2 33338:[DB05630 DB01373] DB05630|Sodium stibogluconate TOP1 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0042493| response to drug TOP1;AOC1 33339:[DB05630 DB01321] DB05630|Sodium stibogluconate TOP1 DB01321|Josamycin rplD;CYP3A4 common genes common pathways 33340:[DB05630 DB00631] DB05630|Sodium stibogluconate TOP1 DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0016310| phosphorylation TOP1;DCK GO:0016032| viral reproduction POLA1;TOP1 GO:0006260| DNA replication RRM1;TOP1;POLA1 GO:0042493| response to drug TOP1;ABCG2 33341:[DB05630 DB08361] DB05630|Sodium stibogluconate TOP1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways GO:0016310| phosphorylation TOP1;SYK GO:0018105| peptidyl-serine phosphorylation SYK;TOP1 GO:0016032| viral reproduction TOP1;SYK 33342:[DB05630 DB07159] DB05630|Sodium stibogluconate TOP1 DB07159|Tamatinib SYK common genes common pathways GO:0016032| viral reproduction TOP1;SYK GO:0018105| peptidyl-serine phosphorylation TOP1;SYK GO:0016310| phosphorylation TOP1;SYK 33343:[DB05630 DB09209] DB05630|Sodium stibogluconate TOP1 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways 33344:[DB05630 DB00114] DB05630|Sodium stibogluconate TOP1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0042493| response to drug GAD2;SRR;GAD1;ABAT;TOP1 GO:0007623| circadian rhythm TOP1;DDC 33345:[DB05630 DB11091] DB05630|Sodium stibogluconate TOP1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0042493| response to drug TOP1;CAT 33346:[DB05630 DB13179] DB05630|Sodium stibogluconate TOP1 DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33347:[DB05630 DB01435] DB05630|Sodium stibogluconate TOP1 DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways GO:0042493| response to drug PTGS2;CYP1A2;TOP1;CYP2E1 33348:[DB05630 DB11640] DB05630|Sodium stibogluconate TOP1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways 33349:[DB05630 DB00898] DB05630|Sodium stibogluconate TOP1 DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0042493| response to drug GABRG3;CYP1A2;TOP1;CYP2E1;CYP1A1 GO:0016032| viral reproduction VCAM1;TOP1 33350:[DB05630 DB00197] DB05630|Sodium stibogluconate TOP1 DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;PPARG;CYP1A1;UGT1A1 GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0007623| circadian rhythm TOP1;SERPINE1 GO:0048511| rhythmic process PPARG;PPARA;TOP1 33351:[DB05630 DB01186] DB05630|Sodium stibogluconate TOP1 DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation TOP1;HTR2B GO:0032922| circadian regulation of gene expression TOP1;DRD3;DRD2 GO:0042493| response to drug DRD3;HTR2C;HTR2B;DRD2;ADRA1A;HTR1B;HTR2A;TOP1;DRD1 GO:0048511| rhythmic process DRD4;TOP1 33352:[DB05630 DB00795] DB05630|Sodium stibogluconate TOP1 DB00795|Sulfasalazine ALOX5;PTGS2;PTGS1;PPARG;CHUK;IKBKB;SLC7A11;ACAT1;TBXAS1;PLA2G1B;ABCG2;ABCC2;SLC46A1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0016310| phosphorylation CHUK;TOP1;IKBKB GO:0018105| peptidyl-serine phosphorylation TOP1;IKBKB;CHUK GO:0048511| rhythmic process PPARG;TOP1 GO:0042493| response to drug ABCG2;ABCC2;PPARG;CHUK;PTGS2;TOP1 33353:[DB05630 DB11569] DB05630|Sodium stibogluconate TOP1 DB11569|Ixekizumab IL17A common genes common pathways 33354:[DB05630 DB01032] DB05630|Sodium stibogluconate TOP1 DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0042493| response to drug TOP1;SLC22A12;ABCC4;UGT1A1;ABCC1;ABCC6;ABCC2 GO:0016032| viral reproduction SLC10A1;TOP1 33355:[DB05630 DB01130] DB05630|Sodium stibogluconate TOP1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 33356:[DB05630 DB06151] DB05630|Sodium stibogluconate TOP1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0018105| peptidyl-serine phosphorylation CHUK;IKBKB;TOP1 GO:0016310| phosphorylation TOP1;IKBKB;CHUK GO:0042493| response to drug GRIN2A;CHUK;TOP1 33357:[DB05630 DB03704] DB05630|Sodium stibogluconate TOP1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways 33358:[DB05630 DB06634] DB05630|Sodium stibogluconate TOP1 DB06634|Casopitant CYP3A4;TACR1 common genes common pathways 33359:[DB05630 DB00628] DB05630|Sodium stibogluconate TOP1 DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;TSPO;GABRG3 33360:[DB05630 DB09089] DB05630|Sodium stibogluconate TOP1 DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways 33361:[DB05630 DB09570] DB05630|Sodium stibogluconate TOP1 DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33362:[DB05630 DB08815] DB05630|Sodium stibogluconate TOP1 DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug DRD2;HTR2A;TOP1 GO:0007623| circadian rhythm HTR7;TOP1 GO:0016032| viral reproduction HTR2A;TOP1 33363:[DB05630 DB00400] DB05630|Sodium stibogluconate TOP1 DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33364:[DB05630 DB01629] DB05630|Sodium stibogluconate TOP1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0042493| response to drug TOP1;SOD1 33365:[DB05630 DB12478] DB05630|Sodium stibogluconate TOP1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 GO:0042493| response to drug TOP1;DRD3;DRD2 33366:[DB05630 DB00468] DB05630|Sodium stibogluconate TOP1 DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;CYP2E1;CYP1A1;ABCB1 33367:[DB05630 DB00208] DB05630|Sodium stibogluconate TOP1 DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1;CYP1A2;CYP1A1 33368:[DB05630 DB01021] DB05630|Sodium stibogluconate TOP1 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways GO:0042493| response to drug TOP1;ATP1A1 33369:[DB05630 DB00824] DB05630|Sodium stibogluconate TOP1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0042493| response to drug ADORA2A;TOP1 33370:[DB05630 DB11834] DB05630|Sodium stibogluconate TOP1 DB11834|Guselkumab IL23A common genes common pathways 33371:[DB05630 DB08906] DB05630|Sodium stibogluconate TOP1 DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 GO:0042493| response to drug ABCB1;TOP1 33372:[DB05630 DB02546] DB05630|Sodium stibogluconate TOP1 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0006338| chromatin remodeling TOP1;HDAC2;HDAC1 GO:0048511| rhythmic process HDAC1;TOP1;HDAC2 GO:0007623| circadian rhythm TOP1;HDAC3 GO:0032922| circadian regulation of gene expression HDAC1;TOP1;HDAC2 GO:0042493| response to drug HDAC1;TOP1;HDAC2 GO:0016032| viral reproduction TOP1;HDAC1 33373:[DB05630 DB11124] DB05630|Sodium stibogluconate TOP1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0042493| response to drug ADRA1A;TOP1 33374:[DB05630 DB01096] DB05630|Sodium stibogluconate TOP1 DB01096|Oxamniquine CYP2D6 common genes common pathways 33375:[DB05630 DB06587] DB05630|Sodium stibogluconate TOP1 DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways 33376:[DB05630 DB07402] DB05630|Sodium stibogluconate TOP1 DB07402|Azapropazone ALB common genes common pathways 33377:[DB05630 DB02209] DB05630|Sodium stibogluconate TOP1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways 33378:[DB05630 DB05749] DB05630|Sodium stibogluconate TOP1 DB05749|MPI-674 CYP19A1 common genes common pathways 33379:[DB05630 DB09363] DB05630|Sodium stibogluconate TOP1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0042493| response to drug TOP1;SLC6A2;MAOB 33380:[DB05630 DB00912] DB05630|Sodium stibogluconate TOP1 DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCC8;TOP1;PPARG GO:0048511| rhythmic process TOP1;PPARG 33381:[DB05630 DB04888] DB05630|Sodium stibogluconate TOP1 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug TOP1;DRD2 33382:[DB05630 DB14010] DB05630|Sodium stibogluconate TOP1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0042493| response to drug HTR2A;TOP1 33383:[DB05630 DB01256] DB05630|Sodium stibogluconate TOP1 DB01256|Retapamulin rplC;CYP3A4 common genes common pathways 33384:[DB05630 DB14509] DB05630|Sodium stibogluconate TOP1 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0048511| rhythmic process GSK3B;TOP1 GO:0007623| circadian rhythm GSK3B;TOP1 GO:0016310| phosphorylation TOP1;GSK3B GO:0018105| peptidyl-serine phosphorylation GSK3B;TOP1 33385:[DB05630 DB04836] DB05630|Sodium stibogluconate TOP1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug TOP1;SLC6A4;SLC6A2 33386:[DB05630 DB00211] DB05630|Sodium stibogluconate TOP1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 33387:[DB05630 DB08895] DB05630|Sodium stibogluconate TOP1 DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0016310| phosphorylation TYK2;TOP1;JAK3;JAK1;JAK2 33388:[DB05630 DB01324] DB05630|Sodium stibogluconate TOP1 DB01324|Polythiazide SLC12A3 common genes common pathways 33389:[DB05630 DB14539] DB05630|Sodium stibogluconate TOP1 DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0042493| response to drug HSD11B2;ANXA1;ABCG2;ABCB1;TOP1 GO:0007059| chromosome segregation TOP1;NR3C1 33390:[DB05630 DB00863] DB05630|Sodium stibogluconate TOP1 DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0042493| response to drug ABCB1;BCHE;TOP1;CYP1A2 GO:0006260| DNA replication ACHE;TOP1 33391:[DB05630 DB05885] DB05630|Sodium stibogluconate TOP1 DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways 33392:[DB05630 DB11127] DB05630|Sodium stibogluconate TOP1 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways 33393:[DB05630 DB09204] DB05630|Sodium stibogluconate TOP1 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0042493| response to drug ADRA1A;TOP1 33394:[DB05630 DB08826] DB05630|Sodium stibogluconate TOP1 DB08826|Deferiprone UGT1A6 common genes common pathways 33395:[DB05630 DB01205] DB05630|Sodium stibogluconate TOP1 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug TOP1;GABRG3 33396:[DB05630 DB09185] DB05630|Sodium stibogluconate TOP1 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;SLC6A2 33397:[DB05630 DB00285] DB05630|Sodium stibogluconate TOP1 DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug SLC6A2;ABCG2;SLC6A3;ABCB1;TOP1;SLC6A4 GO:0007623| circadian rhythm SLC6A4;TOP1 33398:[DB05630 DB06013] DB05630|Sodium stibogluconate TOP1 DB06013|Aldoxorubicin TOP2A common genes common pathways GO:0048511| rhythmic process TOP1;TOP2A GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP1;TOP2A GO:0006265| DNA topological change TOP1;TOP2A GO:0040016| embryonic cleavage TOP1;TOP2A 33399:[DB05630 DB05968] DB05630|Sodium stibogluconate TOP1 DB05968|PR-104 TNF common genes common pathways 33400:[DB05630 DB14004] DB05630|Sodium stibogluconate TOP1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways 33401:[DB05630 DB00708] DB05630|Sodium stibogluconate TOP1 DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways 33402:[DB05630 DB09148] DB05630|Sodium stibogluconate TOP1 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways 33403:[DB05630 DB00390] DB05630|Sodium stibogluconate TOP1 DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1;ABCB1 33404:[DB05630 DB00407] DB05630|Sodium stibogluconate TOP1 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 33405:[DB05630 DB00822] DB05630|Sodium stibogluconate TOP1 DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 33406:[DB05630 DB00966] DB05630|Sodium stibogluconate TOP1 DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways GO:0042493| response to drug PPARG;ABCG2;ABCC2;ABCB1;TOP1 GO:0048511| rhythmic process PPARG;TOP1 33407:[DB05630 DB05014] DB05630|Sodium stibogluconate TOP1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0042493| response to drug TOP1;RET GO:0016310| phosphorylation RET;TOP1;FGFR1;FLT3;KDR;FGFR3;PDGFRB GO:0016032| viral reproduction TOP1;KDR 33408:[DB05630 DB09378] DB05630|Sodium stibogluconate TOP1 DB09378|Fluprednisolone CYP3A4 common genes common pathways 33409:[DB05630 DB12026] DB05630|Sodium stibogluconate TOP1 DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;TOP1;CYP1A2 33410:[DB05630 DB00215] DB05630|Sodium stibogluconate TOP1 DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A2;ADRA1A;ABCB1;HTR2C;SLC6A3;CYP1A2;TOP1;CYP2E1;SLC6A4 GO:0007623| circadian rhythm TOP1;SLC6A4 33411:[DB05630 DB00250] DB05630|Sodium stibogluconate TOP1 DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways GO:0042493| response to drug TOP1;PTGS2;CYP2E1 33412:[DB05630 DB00980] DB05630|Sodium stibogluconate TOP1 DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 GO:0007623| circadian rhythm TOP1;MTNR1A;MTNR1B 33413:[DB05630 DB00241] DB05630|Sodium stibogluconate TOP1 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;TOP1 33414:[DB05630 DB00467] DB05630|Sodium stibogluconate TOP1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0048511| rhythmic process TOP2A;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0042493| response to drug CYP1A2;TOP1 GO:0016925| protein sumoylation TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP1 GO:0040016| embryonic cleavage TOP1;TOP2A 33415:[DB05630 DB08837] DB05630|Sodium stibogluconate TOP1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways 33416:[DB05630 DB03336] DB05630|Sodium stibogluconate TOP1 DB03336|BIA COMT common genes common pathways GO:0042493| response to drug COMT;TOP1 33417:[DB05630 DB12693] DB05630|Sodium stibogluconate TOP1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0042493| response to drug TOP1;HTR2A 33418:[DB05630 DB09124] DB05630|Sodium stibogluconate TOP1 DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways 33419:[DB05630 DB00013] DB05630|Sodium stibogluconate TOP1 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0007623| circadian rhythm TOP1;SERPINE1 33420:[DB05630 DB00206] DB05630|Sodium stibogluconate TOP1 DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0042493| response to drug ABCC2;ABCB1;TOP1 GO:0016925| protein sumoylation BIRC5;TOP1 GO:0007059| chromosome segregation TOP1;BIRC5 33421:[DB05630 DB01222] DB05630|Sodium stibogluconate TOP1 DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 33422:[DB05630 DB06446] DB05630|Sodium stibogluconate TOP1 DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2A;TOP1;HTR2C GO:0016032| viral reproduction HTR2A;TOP1 33423:[DB05630 DB09383] DB05630|Sodium stibogluconate TOP1 DB09383|Meprednisone CYP3A4;ALB common genes common pathways 33424:[DB05630 DB01403] DB05630|Sodium stibogluconate TOP1 DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0048511| rhythmic process TOP1;DRD4 GO:0032922| circadian regulation of gene expression DRD2;DRD3;TOP1 GO:0042493| response to drug DRD3;HTR2C;DRD2;ADRA1A;HTR2A;CYP2E1;TOP1;DRD1 GO:0016032| viral reproduction HTR2A;TOP1 33425:[DB05630 DB14009] DB05630|Sodium stibogluconate TOP1 DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0048511| rhythmic process AANAT;TOP1;PPARG GO:0042493| response to drug CAT;HTR2A;SOD1;TOP1;CYP1A2;PTGS2;ABCG2;TRPA1;PPARG;CYP1A1;SMPD1;ABCC1 GO:0007623| circadian rhythm AANAT;TOP1 GO:0016032| viral reproduction VDAC1;TOP1;HTR2A 33426:[DB05630 DB00137] DB05630|Sodium stibogluconate TOP1 DB00137|Lutein ALB common genes common pathways 33427:[DB05630 DB08954] DB05630|Sodium stibogluconate TOP1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways 33428:[DB05630 DB01345] DB05630|Sodium stibogluconate TOP1 DB01345|Potassium cation ATP1A1 common genes common pathways GO:0042493| response to drug TOP1;ATP1A1 33429:[DB05630 DB11338] DB05630|Sodium stibogluconate TOP1 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0042493| response to drug COL1A1;TOP1 GO:0016032| viral reproduction VCAM1;TOP1 33430:[DB05630 DB00505] DB05630|Sodium stibogluconate TOP1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways 33431:[DB05630 DB00166] DB05630|Sodium stibogluconate TOP1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0042493| response to drug POR;TOP1 33432:[DB05630 DB11635] DB05630|Sodium stibogluconate TOP1 DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0016032| viral reproduction SCARB1;TOP1 GO:0042493| response to drug ABCA1;TOP1;ABCG8;ABCG5;ABCB1;NPC1L1 33433:[DB05630 DB00837] DB05630|Sodium stibogluconate TOP1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways 33434:[DB05630 DB06785] DB05630|Sodium stibogluconate TOP1 DB06785|Ganirelix GNRHR common genes common pathways 33435:[DB05630 DB13620] DB05630|Sodium stibogluconate TOP1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0042493| response to drug TOP1;ATP1A1 33436:[DB05630 DB14071] DB05630|Sodium stibogluconate TOP1 DB14071|Desmethylsertraline ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33437:[DB05630 DB00381] DB05630|Sodium stibogluconate TOP1 DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;SMPD1;TOP1 33438:[DB05630 DB01173] DB05630|Sodium stibogluconate TOP1 DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0042493| response to drug SLC6A2;CYP1A2;TOP1;CYP2E1 33439:[DB05630 DB00915] DB05630|Sodium stibogluconate TOP1 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0007623| circadian rhythm TOP1;DDC GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug TOP1;DRD2;MAOB 33440:[DB05630 DB06706] DB05630|Sodium stibogluconate TOP1 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 33441:[DB05630 DB00214] DB05630|Sodium stibogluconate TOP1 DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways 33442:[DB05630 DB11792] DB05630|Sodium stibogluconate TOP1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 33443:[DB05630 DB03856] DB05630|Sodium stibogluconate TOP1 DB03856|L-Eflornithine ODC1 common genes common pathways 33444:[DB05630 DB01120] DB05630|Sodium stibogluconate TOP1 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0042493| response to drug TOP1;ABCC8 33445:[DB05630 DB07339] DB05630|Sodium stibogluconate TOP1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways 33446:[DB05630 DB04956] DB05630|Sodium stibogluconate TOP1 DB04956|Afelimomab TNF common genes common pathways 33447:[DB05630 DB00423] DB05630|Sodium stibogluconate TOP1 DB00423|Methocarbamol CA1 common genes common pathways 33448:[DB05630 DB06726] DB05630|Sodium stibogluconate TOP1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways 33449:[DB05630 DB11477] DB05630|Sodium stibogluconate TOP1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways 33450:[DB05630 DB00244] DB05630|Sodium stibogluconate TOP1 DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;IKBKB;CHUK GO:0016310| phosphorylation TOP1;IKBKB;CHUK GO:0042493| response to drug PPARG;CHUK;PTGS2;TOP1 GO:0048511| rhythmic process TOP1;PPARG 33451:[DB05630 DB11274] DB05630|Sodium stibogluconate TOP1 DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0042493| response to drug DRD3;DRD2;TOP1;DRD1 GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 33452:[DB05630 DB00274] DB05630|Sodium stibogluconate TOP1 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways 33453:[DB05630 DB01352] DB05630|Sodium stibogluconate TOP1 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways 33454:[DB05630 DB06468] DB05630|Sodium stibogluconate TOP1 DB06468|Cariporide SLC9A1;MPO common genes common pathways 33455:[DB05630 DB14185] DB05630|Sodium stibogluconate TOP1 DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0048511| rhythmic process TOP1;DRD4 GO:0007623| circadian rhythm HTR7;TOP1 GO:0032922| circadian regulation of gene expression TOP1;DRD3;DRD2 GO:0042493| response to drug TOP1;HTR2A;DRD1;DRD3;ADRA1A;DRD2;HTR1B;HTR2C GO:0016032| viral reproduction TOP1;HTR2A 33456:[DB05630 DB01044] DB05630|Sodium stibogluconate TOP1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33457:[DB05630 DB00759] DB05630|Sodium stibogluconate TOP1 DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways GO:0006338| chromatin remodeling PADI4;TOP1 33458:[DB05630 DB04894] DB05630|Sodium stibogluconate TOP1 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways 33459:[DB05630 DB01206] DB05630|Sodium stibogluconate TOP1 DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways 33460:[DB05630 DB09079] DB05630|Sodium stibogluconate TOP1 DB09079|Nintedanib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FLT3;LCK;LYN;SRC;CYP3A4;ABCB1 common genes common pathways GO:0016032| viral reproduction KDR;LCK;LYN;SRC;TOP1 GO:0018105| peptidyl-serine phosphorylation SRC;TOP1 GO:0016310| phosphorylation SRC;FGFR2;FLT1;TOP1;FGFR1;FLT3;LCK;KDR;FGFR3;FLT4;LYN GO:0042493| response to drug SRC;TOP1;ABCB1;LCK;LYN 33461:[DB05630 DB12001] DB05630|Sodium stibogluconate TOP1 DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0016310| phosphorylation CDK6;CDK4;TOP1 GO:0042493| response to drug OTC;TOP1;CDK4;ABCG2;ABCB1 GO:0007623| circadian rhythm CDK4;TOP1 33462:[DB05630 DB07525] DB05630|Sodium stibogluconate TOP1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways GO:0016310| phosphorylation FGFR1;TOP1 33463:[DB05630 DB08953] DB05630|Sodium stibogluconate TOP1 DB08953|Indalpine CYP3A4 common genes common pathways 33464:[DB05630 DB01131] DB05630|Sodium stibogluconate TOP1 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 33465:[DB05630 DB00421] DB05630|Sodium stibogluconate TOP1 DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug TOP1;SRD5A2;SRD5A1;ABCB1;ABCC2 33466:[DB05630 DB00572] DB05630|Sodium stibogluconate TOP1 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways 33467:[DB05630 DB01045] DB05630|Sodium stibogluconate TOP1 DB01045|Rifampicin rpoB;rpoC;NR1I2;SLCO1B1;SLCO1A2;SLCO1B3;CYP51A1;ALB;SLCO2B1;CYP2C9;CYP1A2;CYP2C8;CYP3A4;CYP2B6;UGT1A1;CYP2C19;CYP2A6;CYP2E1;CYP3A43;CYP3A7;CYP4A11;CYP2D6;ABCB1;SLCO1B3;ABCC1;SLCO2B1;ABCB11;SLCO1A2;SLC22A7;SLCO1B1;ABCC5;ABCC2;ABCC3;SLC22A6;SLC22A8 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;CYP2E1;ABCB1;ABCC2;ABCC1;UGT1A1 33468:[DB05630 DB05339] DB05630|Sodium stibogluconate TOP1 DB05339|MN-305 HTR1A common genes common pathways 33469:[DB05630 DB00415] DB05630|Sodium stibogluconate TOP1 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0016310| phosphorylation TEK;TOP1 33470:[DB05630 DB00110] DB05630|Sodium stibogluconate TOP1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction TOP1;FCGR2B 33471:[DB05630 DB00312] DB05630|Sodium stibogluconate TOP1 DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0042493| response to drug GABRG3;GRIN2A;TOP1 33472:[DB05630 DB01094] DB05630|Sodium stibogluconate TOP1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;TOP1;CYP1A2 33473:[DB05630 DB05139] DB05630|Sodium stibogluconate TOP1 DB05139|CR002 PDGFD common genes common pathways 33474:[DB05630 DB11275] DB05630|Sodium stibogluconate TOP1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0042493| response to drug DRD1;TOP1;DRD2;DRD3 GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0048511| rhythmic process TOP1;DRD4 33475:[DB05630 DB00650] DB05630|Sodium stibogluconate TOP1 DB00650|Leucovorin SLC22A8 common genes common pathways 33476:[DB05630 DB08980] DB05630|Sodium stibogluconate TOP1 DB08980|Fendiline CYP3A4 common genes common pathways 33477:[DB05630 DB09183] DB05630|Sodium stibogluconate TOP1 DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;TOP1 33478:[DB05630 DB00111] DB05630|Sodium stibogluconate TOP1 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction IL2RB;FCGR2B;TOP1 33479:[DB05630 DB01030] DB05630|Sodium stibogluconate TOP1 DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes TOP1 common pathways GO:0006265| DNA topological change TOP1MT;TOP1 GO:0016310| phosphorylation TOP1 GO:0016032| viral reproduction TOP1 GO:0040016| embryonic cleavage TOP1 GO:0006260| DNA replication TOP1MT;TOP1 GO:0018105| peptidyl-serine phosphorylation TOP1 GO:0012501| programmed cell death TOP1 GO:0048511| rhythmic process TOP1 GO:0006338| chromatin remodeling TOP1MT;TOP1 GO:0032922| circadian regulation of gene expression TOP1 GO:0016925| protein sumoylation TOP1 GO:0042493| response to drug ABCG2;ABCB1;TOP1 GO:0007059| chromosome segregation TOP1MT;TOP1 GO:0007623| circadian rhythm TOP1 33480:[DB05630 DB13933] DB05630|Sodium stibogluconate TOP1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0007623| circadian rhythm TOP1;F7 33481:[DB05630 DB13948] DB05630|Sodium stibogluconate TOP1 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0042493| response to drug TOP1;HTR2A 33482:[DB05630 DB01466] DB05630|Sodium stibogluconate TOP1 DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug POR;TOP1 33483:[DB05630 DB00568] DB05630|Sodium stibogluconate TOP1 DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug DRD2;CYP1A1;DRD1;TOP1;CYP1A2 33484:[DB05630 DB07768] DB05630|Sodium stibogluconate TOP1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways 33485:[DB05630 DB05482] DB05630|Sodium stibogluconate TOP1 DB05482|7-ethyl-10-hydroxycamptothecin TOP1;CYP3A4 common genes TOP1 common pathways GO:0016032| viral reproduction TOP1 GO:0040016| embryonic cleavage TOP1 GO:0006260| DNA replication TOP1 GO:0018105| peptidyl-serine phosphorylation TOP1 GO:0006265| DNA topological change TOP1 GO:0016310| phosphorylation TOP1 GO:0032922| circadian regulation of gene expression TOP1 GO:0016925| protein sumoylation TOP1 GO:0042493| response to drug TOP1 GO:0007059| chromosome segregation TOP1 GO:0007623| circadian rhythm TOP1 GO:0012501| programmed cell death TOP1 GO:0048511| rhythmic process TOP1 GO:0006338| chromatin remodeling TOP1 33486:[DB05630 DB01053] DB05630|Sodium stibogluconate TOP1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways 33487:[DB05630 DB03907] DB05630|Sodium stibogluconate TOP1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0042493| response to drug TOP1;COMT 33488:[DB05630 DB01085] DB05630|Sodium stibogluconate TOP1 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 33489:[DB05630 DB12773] DB05630|Sodium stibogluconate TOP1 DB12773|Sifalimumab IFNA2 common genes common pathways 33490:[DB05630 DB00227] DB05630|Sodium stibogluconate TOP1 DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0006338| chromatin remodeling HDAC2;TOP1 GO:0048511| rhythmic process TOP1;HDAC2 GO:0042493| response to drug HDAC2;TOP1;ABCB1;ABCC2;UGT1A1 GO:0032922| circadian regulation of gene expression TOP1;HDAC2 33491:[DB05630 DB01645] DB05630|Sodium stibogluconate TOP1 DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes common pathways GO:0006265| DNA topological change TOP2A;TOP1 GO:0016310| phosphorylation TOP1;AKT1;PTK2B GO:0040016| embryonic cleavage TOP1;TOP2A GO:0018105| peptidyl-serine phosphorylation AKT1;TOP1 GO:0048511| rhythmic process TOP1;TOP2A;NCOA2 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0042493| response to drug ABCC1;ABCB1;PTK2B;ABCG2;TOP1;CYP1A2 GO:0016925| protein sumoylation TOP1;TOP2A GO:0032922| circadian regulation of gene expression TOP1;NCOA2 GO:0007623| circadian rhythm NCOA2;TOP1 GO:0007059| chromosome segregation TOP2A;TOP1 33492:[DB05630 DB00883] DB05630|Sodium stibogluconate TOP1 DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 33493:[DB05630 DB01033] DB05630|Sodium stibogluconate TOP1 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0042493| response to drug TOP1;PPAT;ABCC4 GO:0007623| circadian rhythm IMPDH2;TOP1 33494:[DB05630 DB06372] DB05630|Sodium stibogluconate TOP1 DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways 33495:[DB05630 DB08814] DB05630|Sodium stibogluconate TOP1 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0007623| circadian rhythm TOP1;NOS2 33496:[DB05630 DB00365] DB05630|Sodium stibogluconate TOP1 DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;ABCC1;ABCB1;ABCC2 33497:[DB05630 DB11619] DB05630|Sodium stibogluconate TOP1 DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0007059| chromosome segregation NR3C1;TOP1 33498:[DB05630 DB09272] DB05630|Sodium stibogluconate TOP1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0042493| response to drug ABCC2;TOP1 33499:[DB05630 DB04871] DB05630|Sodium stibogluconate TOP1 DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;HTR2C;CYP1A1 33500:[DB05630 DB00294] DB05630|Sodium stibogluconate TOP1 DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 33501:[DB05630 DB00657] DB05630|Sodium stibogluconate TOP1 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways 33502:[DB05630 DB08844] DB05630|Sodium stibogluconate TOP1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways 33503:[DB05630 DB01182] DB05630|Sodium stibogluconate TOP1 DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;ABCB1 33504:[DB05630 DB01104] DB05630|Sodium stibogluconate TOP1 DB01104|Sertraline SLC6A4;SLC6A3;PGRMC1;SIGMAR1;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP2B6;MAOB;MAOA;CYP2B;ALB;ABCB1 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug MAOB;ABCB1;SLC6A3;TOP1;SLC6A4 33505:[DB05630 DB00810] DB05630|Sodium stibogluconate TOP1 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways 33506:[DB05630 DB01018] DB05630|Sodium stibogluconate TOP1 DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways 33507:[DB05630 DB01405] DB05630|Sodium stibogluconate TOP1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33508:[DB05630 DB13873] DB05630|Sodium stibogluconate TOP1 DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes common pathways GO:0048511| rhythmic process TOP1;PPARA;PPARG GO:0042493| response to drug PPARG;TOP1 GO:0032922| circadian regulation of gene expression TOP1;PPARA 33509:[DB05630 DB05361] DB05630|Sodium stibogluconate TOP1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways 33510:[DB05630 DB01409] DB05630|Sodium stibogluconate TOP1 DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways 33511:[DB05630 DB00812] DB05630|Sodium stibogluconate TOP1 DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 33512:[DB05630 DB00512] DB05630|Sodium stibogluconate TOP1 DB00512|Vancomycin ALB;ORM1;ORM2 common genes common pathways 33513:[DB05630 DB00865] DB05630|Sodium stibogluconate TOP1 DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0042493| response to drug ADRA1A;POR;SLC6A3;TOP1 33514:[DB05630 DB13941] DB05630|Sodium stibogluconate TOP1 DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 33515:[DB05630 DB00160] DB05630|Sodium stibogluconate TOP1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0042493| response to drug ABAT;TOP1 33516:[DB05630 DB00764] DB05630|Sodium stibogluconate TOP1 DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 33517:[DB05630 DB00596] DB05630|Sodium stibogluconate TOP1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 33518:[DB05630 DB00694] DB05630|Sodium stibogluconate TOP1 DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP2B;TOP1 GO:0042493| response to drug ABCB1;POR;ABCC2;ABCG2;ABCC1;ABCC6;CYP1A1;TOP1 GO:0016925| protein sumoylation TOP2A;TOP1;TOP2B GO:0007059| chromosome segregation TOP1;TOP2A GO:0048511| rhythmic process TOP2A;TOP1 33519:[DB05630 DB00094] DB05630|Sodium stibogluconate TOP1 DB00094|Urofollitropin FSHR common genes common pathways 33520:[DB05630 DB00189] DB05630|Sodium stibogluconate TOP1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;TOP1 33521:[DB05630 DB09395] DB05630|Sodium stibogluconate TOP1 DB09395|Sodium acetate ACSS2 common genes common pathways 33522:[DB05630 DB01366] DB05630|Sodium stibogluconate TOP1 DB01366|Procaterol ADRB2 common genes common pathways 33523:[DB05630 DB00385] DB05630|Sodium stibogluconate TOP1 DB00385|Valrubicin TOP2A common genes common pathways GO:0016925| protein sumoylation TOP2A;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP1;TOP2A 33524:[DB05630 DB14596] DB05630|Sodium stibogluconate TOP1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 33525:[DB05630 DB01656] DB05630|Sodium stibogluconate TOP1 DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways 33526:[DB05630 DB01440] DB05630|Sodium stibogluconate TOP1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 33527:[DB05630 DB08874] DB05630|Sodium stibogluconate TOP1 DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33528:[DB05630 DB13036] DB05630|Sodium stibogluconate TOP1 DB13036|Ramatroban PTGDR2 common genes common pathways 33529:[DB05630 DB01144] DB05630|Sodium stibogluconate TOP1 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 33530:[DB05630 DB12781] DB05630|Sodium stibogluconate TOP1 DB12781|Balaglitazone CYP3A4;CYP2C8 common genes common pathways 33531:[DB05630 DB00558] DB05630|Sodium stibogluconate TOP1 DB00558|Zanamivir NEU2 common genes common pathways 33532:[DB05630 DB01623] DB05630|Sodium stibogluconate TOP1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0042493| response to drug DRD2;CYP1A2;TOP1;HTR2A;DRD1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0016032| viral reproduction HTR2A;TOP1 33533:[DB05630 DB00033] DB05630|Sodium stibogluconate TOP1 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 33534:[DB05630 DB00857] DB05630|Sodium stibogluconate TOP1 DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33535:[DB05630 DB04829] DB05630|Sodium stibogluconate TOP1 DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2B;TOP1 GO:0016310| phosphorylation HTR2B;TOP1 33536:[DB05630 DB13997] DB05630|Sodium stibogluconate TOP1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways 33537:[DB05630 DB01083] DB05630|Sodium stibogluconate TOP1 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways 33538:[DB05630 DB14582] DB05630|Sodium stibogluconate TOP1 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways 33539:[DB05630 DB00691] DB05630|Sodium stibogluconate TOP1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0016032| viral reproduction ACE2;TOP1 33540:[DB05630 DB05442] DB05630|Sodium stibogluconate TOP1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways 33541:[DB05630 DB09060] DB05630|Sodium stibogluconate TOP1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0042493| response to drug TOP1;ABCC2 33542:[DB05630 DB00434] DB05630|Sodium stibogluconate TOP1 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0007623| circadian rhythm TOP1;HTR7 GO:0042493| response to drug TOP1;HTR2A;HTR2C GO:0016032| viral reproduction TOP1;HTR2A 33543:[DB05630 DB00949] DB05630|Sodium stibogluconate TOP1 DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0042493| response to drug GRIN2A;CYP2E1;TOP1 33544:[DB05630 DB08912] DB05630|Sodium stibogluconate TOP1 DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;TOP1 GO:0048511| rhythmic process SIK1;TOP1 GO:0016310| phosphorylation LIMK1;NEK11;BRAF;TOP1;RAF1;SIK1 33545:[DB05630 DB12465] DB05630|Sodium stibogluconate TOP1 DB12465|Ketanserin HTR2A common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0042493| response to drug HTR2A;TOP1 33546:[DB05630 DB09258] DB05630|Sodium stibogluconate TOP1 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways 33547:[DB05630 DB09046] DB05630|Sodium stibogluconate TOP1 DB09046|Metreleptin LEPR common genes common pathways 33548:[DB05630 DB05936] DB05630|Sodium stibogluconate TOP1 DB05936|CVT-6883 ADORA2B common genes common pathways 33549:[DB05630 DB00347] DB05630|Sodium stibogluconate TOP1 DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 33550:[DB05630 DB11755] DB05630|Sodium stibogluconate TOP1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0042493| response to drug TRPA1;TOP1 33551:[DB05630 DB00378] DB05630|Sodium stibogluconate TOP1 DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways 33552:[DB05630 DB01005] DB05630|Sodium stibogluconate TOP1 DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways GO:0006260| DNA replication RRM1;TOP1 33553:[DB05630 DB08918] DB05630|Sodium stibogluconate TOP1 DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;SLC6A4;TOP1 GO:0007623| circadian rhythm TOP1;SLC6A4 33554:[DB05630 DB01998] DB05630|Sodium stibogluconate TOP1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways 33555:[DB05630 DB13168] DB05630|Sodium stibogluconate TOP1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 33556:[DB05630 DB03066] DB05630|Sodium stibogluconate TOP1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 33557:[DB05630 DB11892] DB05630|Sodium stibogluconate TOP1 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33558:[DB05630 DB06756] DB05630|Sodium stibogluconate TOP1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0042493| response to drug BCHE;TOP1;BCL2 GO:0018105| peptidyl-serine phosphorylation TOP1;BCL2 33559:[DB05630 DB00787] DB05630|Sodium stibogluconate TOP1 DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways 33560:[DB05630 DB09332] DB05630|Sodium stibogluconate TOP1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0042493| response to drug POR;TOP1 GO:0007623| circadian rhythm TOP1;F7 33561:[DB05630 DB01170] DB05630|Sodium stibogluconate TOP1 DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways GO:0042493| response to drug SLC6A2;TOP1 33562:[DB05630 DB00029] DB05630|Sodium stibogluconate TOP1 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm TOP1;SERPINE1 33563:[DB05630 DB03023] DB05630|Sodium stibogluconate TOP1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;SRC GO:0016032| viral reproduction SRC;TOP1;LCK;LYN GO:0016310| phosphorylation LYN;LCK;TOP1;SRC GO:0042493| response to drug LCK;LYN;SRC;TOP1 33564:[DB05630 DB11779] DB05630|Sodium stibogluconate TOP1 DB11779|Danoprevir CYP3A4 common genes common pathways 33565:[DB05630 DB00550] DB05630|Sodium stibogluconate TOP1 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A1 33566:[DB05630 DB06419] DB05630|Sodium stibogluconate TOP1 DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways 33567:[DB05630 DB11960] DB05630|Sodium stibogluconate TOP1 DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways 33568:[DB05630 DB09052] DB05630|Sodium stibogluconate TOP1 DB09052|Blinatumomab CD19;CD3D common genes common pathways 33569:[DB05630 DB08834] DB05630|Sodium stibogluconate TOP1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways 33570:[DB05630 DB01129] DB05630|Sodium stibogluconate TOP1 DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;CYP1A1;TOP1;CYP1A2 33571:[DB05630 DB06589] DB05630|Sodium stibogluconate TOP1 DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;UGT1A1;ABCB1;ABCG2 GO:0016310| phosphorylation KIT;ITK;TOP1;FLT1;KDR;PDGFRA;FLT4;PDGFRB;FGFR3 GO:0016032| viral reproduction TOP1;PDGFRA;KDR 33572:[DB05630 DB03153] DB05630|Sodium stibogluconate TOP1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 33573:[DB05630 DB12489] DB05630|Sodium stibogluconate TOP1 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways 33574:[DB05630 DB00698] DB05630|Sodium stibogluconate TOP1 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0042493| response to drug ABCG2;POR;TOP1 33575:[DB05630 DB01261] DB05630|Sodium stibogluconate TOP1 DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33576:[DB05630 DB00145] DB05630|Sodium stibogluconate TOP1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0042493| response to drug GRIN2A;TOP1 33577:[DB05630 DB08892] DB05630|Sodium stibogluconate TOP1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways 33578:[DB05630 DB00830] DB05630|Sodium stibogluconate TOP1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A2;SLC6A3;TOP1 33579:[DB05630 DB11805] DB05630|Sodium stibogluconate TOP1 DB11805|Saracatinib CYP3A4 common genes common pathways 33580:[DB05630 DB01708] DB05630|Sodium stibogluconate TOP1 DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug GRIN2A;GABRG3;TOP1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process TOP1;PPARA 33581:[DB05630 DB01108] DB05630|Sodium stibogluconate TOP1 DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 33582:[DB05630 DB04861] DB05630|Sodium stibogluconate TOP1 DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways 33583:[DB05630 DB00052] DB05630|Sodium stibogluconate TOP1 DB00052|Somatotropin GHR;PRLR common genes common pathways 33584:[DB05630 DB12243] DB05630|Sodium stibogluconate TOP1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways 33585:[DB05630 DB09198] DB05630|Sodium stibogluconate TOP1 DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG;TOP1;CYP1A2 GO:0048511| rhythmic process PPARG;TOP1 33586:[DB05630 DB05449] DB05630|Sodium stibogluconate TOP1 DB05449|FM-VP4 ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33587:[DB05630 DB09348] DB05630|Sodium stibogluconate TOP1 DB09348|Propiolactone ALB common genes common pathways 33588:[DB05630 DB06733] DB05630|Sodium stibogluconate TOP1 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 33589:[DB05630 DB02056] DB05630|Sodium stibogluconate TOP1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways 33590:[DB05630 DB01294] DB05630|Sodium stibogluconate TOP1 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 33591:[DB05630 DB04665] DB05630|Sodium stibogluconate TOP1 DB04665|Coumarin CYP2A6;CYP2C9 common genes common pathways 33592:[DB05630 DB06643] DB05630|Sodium stibogluconate TOP1 DB06643|Denosumab TNFSF11 common genes common pathways 33593:[DB05630 DB04821] DB05630|Sodium stibogluconate TOP1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug SLC6A3;MAOB;SLC6A2;SLC6A4;TOP1 33594:[DB05630 DB00193] DB05630|Sodium stibogluconate TOP1 DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug SLC6A2;UGT1A1;HTR2C;TOP1;SLC6A4 33595:[DB05630 DB01022] DB05630|Sodium stibogluconate TOP1 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 33596:[DB05630 DB01075] DB05630|Sodium stibogluconate TOP1 DB01075|Diphenhydramine HRH1;CHRM2;CYP2D6;CYP2C9;CYP2C19;CYP2C18;PTGS1;SLC22A2;SLC22A5 common genes common pathways 33597:[DB05630 DB04576] DB05630|Sodium stibogluconate TOP1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0007059| chromosome segregation TOP2A;TOP1 GO:0016925| protein sumoylation TOP2A;TOP1 GO:0042493| response to drug CYP1A2;TOP1 GO:0048511| rhythmic process TOP2A;TOP1 GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP1;TOP2A 33598:[DB05630 DB02337] DB05630|Sodium stibogluconate TOP1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 33599:[DB05630 DB14641] DB05630|Sodium stibogluconate TOP1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0006338| chromatin remodeling TOP1;ESR1 33600:[DB05630 DB13998] DB05630|Sodium stibogluconate TOP1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0042493| response to drug CALR;TOP1 33601:[DB05630 DB04877] DB05630|Sodium stibogluconate TOP1 DB04877|Voacamine ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33602:[DB05630 DB00611] DB05630|Sodium stibogluconate TOP1 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways 33603:[DB05630 DB02105] DB05630|Sodium stibogluconate TOP1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0042493| response to drug TOP1;COMT 33604:[DB05630 DB09072] DB05630|Sodium stibogluconate TOP1 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways 33605:[DB05630 DB03203] DB05630|Sodium stibogluconate TOP1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0016032| viral reproduction TOP1;PVR 33606:[DB05630 DB13988] DB05630|Sodium stibogluconate TOP1 DB13988|SB-269970 HTR7 common genes common pathways GO:0007623| circadian rhythm TOP1;HTR7 33607:[DB05630 DB01049] DB05630|Sodium stibogluconate TOP1 DB01049|Ergoloid mesylate DRD1;DRD5;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;CYP3A4 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation TOP1;HTR2B GO:0042493| response to drug TOP1;HTR2A;DRD1;DRD3;HTR1B;DRD2;ADRA1A;HTR2C;HTR2B GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0007623| circadian rhythm HTR7;TOP1 GO:0048511| rhythmic process DRD4;TOP1 33608:[DB05630 DB00726] DB05630|Sodium stibogluconate TOP1 DB00726|Trimipramine SLC6A4;SLC6A2;SLC6A3;HTR2A;HTR1A;ADRA1A;ADRA1B;DRD2;ADRA2B;HRH1;HTR2C;HTR3A;HTR1D;ADRA2A;DRD1;DRD5;ADRB1;ADRB2;ADRB3;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug ABCB1;DRD2;ADRA1A;HTR2C;SLC6A3;SLC6A2;SLC6A4;DRD1;TOP1;HTR2A GO:0016032| viral reproduction HTR2A;TOP1 33609:[DB05630 DB11726] DB05630|Sodium stibogluconate TOP1 DB11726|Encenicline CHRNA7 common genes common pathways 33610:[DB05630 DB00745] DB05630|Sodium stibogluconate TOP1 DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;SLC6A3 33611:[DB05630 DB06770] DB05630|Sodium stibogluconate TOP1 DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;CYP2E1;CYP1A1 33612:[DB05630 DB01234] DB05630|Sodium stibogluconate TOP1 DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0007623| circadian rhythm NOS2;TOP1 GO:0042493| response to drug CYP2E1;TOP1;ABCC2;ABCG2;ANXA1;ABCB1;CYP1A1 33613:[DB05630 DB00779] DB05630|Sodium stibogluconate TOP1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways 33614:[DB05630 DB01016] DB05630|Sodium stibogluconate TOP1 DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes common pathways GO:0007623| circadian rhythm TOP1;CPT1A GO:0042493| response to drug ABCC8;KCNJ11;ABCA1;TOP1;CPT1A;ABCC9;ABCC1;ABCC2;ABCG2;ABCB1 33615:[DB05630 DB05928] DB05630|Sodium stibogluconate TOP1 DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;CYP1A2;TOP1 33616:[DB05630 DB01562] DB05630|Sodium stibogluconate TOP1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways 33617:[DB05630 DB13952] DB05630|Sodium stibogluconate TOP1 DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;BECN1;UGT1A1;CYP1A1;ABCB1;ABCG2 GO:0032922| circadian regulation of gene expression TOP1;NCOA2 GO:0007623| circadian rhythm NCOA2;TOP1 GO:0048511| rhythmic process TOP1;NCOA2 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0016032| viral reproduction TOP1;BECN1 33618:[DB05630 DB00016] DB05630|Sodium stibogluconate TOP1 DB00016|Erythropoietin EPOR common genes common pathways 33619:[DB05630 DB06704] DB05630|Sodium stibogluconate TOP1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0042493| response to drug TOP1;SLC6A2 33620:[DB05630 DB00142] DB05630|Sodium stibogluconate TOP1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0042493| response to drug GCLM;SLC1A2;GAD2;SLC1A3;GAD1;ABAT;PFAS;TOP1;GRIN2A GO:0016310| phosphorylation TOP1;ALDH18A1 33621:[DB05630 DB00872] DB05630|Sodium stibogluconate TOP1 DB00872|Conivaptan AVPR1A;AVPR2;CYP3A4 common genes common pathways 33622:[DB05630 DB00439] DB05630|Sodium stibogluconate TOP1 DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCG2;ABCC2;ABCB1;UGT1A1;TOP1 33623:[DB05630 DB00593] DB05630|Sodium stibogluconate TOP1 DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 33624:[DB05630 DB00508] DB05630|Sodium stibogluconate TOP1 DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0042493| response to drug BCHE;DRD2;ABCB1;HTR2B;TOP1;DRD1 GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0016310| phosphorylation TOP1;HTR2B 33625:[DB05630 DB06594] DB05630|Sodium stibogluconate TOP1 DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0042493| response to drug HTR2C;CYP1A2;TOP1 GO:0007623| circadian rhythm TOP1;MTNR1A;MTNR1B 33626:[DB05630 DB13173] DB05630|Sodium stibogluconate TOP1 DB13173|Cerliponase alfa IGF2R common genes common pathways 33627:[DB05630 DB06680] DB05630|Sodium stibogluconate TOP1 DB06680|Asoprisnil PGR common genes common pathways 33628:[DB05630 DB00486] DB05630|Sodium stibogluconate TOP1 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 33629:[DB05630 DB05120] DB05630|Sodium stibogluconate TOP1 DB05120|AT1391 INSR common genes common pathways GO:0016310| phosphorylation INSR;TOP1 33630:[DB05630 DB09207] DB05630|Sodium stibogluconate TOP1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 GO:0042493| response to drug DRD3;DRD2;TOP1 33631:[DB05630 DB00198] DB05630|Sodium stibogluconate TOP1 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0042493| response to drug TOP1;ABCC4 33632:[DB05630 DB00188] DB05630|Sodium stibogluconate TOP1 DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 GO:0016032| viral reproduction TOP1;PSMB1;PSMB5 33633:[DB05630 DB08871] DB05630|Sodium stibogluconate TOP1 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0018105| peptidyl-serine phosphorylation BCL2;TOP1 GO:0042493| response to drug TOP1;BCL2 33634:[DB05630 DB05996] DB05630|Sodium stibogluconate TOP1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways 33635:[DB05630 DB05915] DB05630|Sodium stibogluconate TOP1 DB05915|MYO-029 MSTN common genes common pathways 33636:[DB05630 DB00304] DB05630|Sodium stibogluconate TOP1 DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 33637:[DB05630 DB09223] DB05630|Sodium stibogluconate TOP1 DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0042493| response to drug DRD3;DRD2;TOP1;HTR2A GO:0016032| viral reproduction HTR2A;TOP1 33638:[DB05630 DB09285] DB05630|Sodium stibogluconate TOP1 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2;TBXA2R 33639:[DB05630 DB03048] DB05630|Sodium stibogluconate TOP1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways 33640:[DB05630 DB01106] DB05630|Sodium stibogluconate TOP1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways 33641:[DB05630 DB01210] DB05630|Sodium stibogluconate TOP1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways 33642:[DB05630 DB06217] DB05630|Sodium stibogluconate TOP1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways 33643:[DB05630 DB07960] DB05630|Sodium stibogluconate TOP1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways 33644:[DB05630 DB02266] DB05630|Sodium stibogluconate TOP1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0048511| rhythmic process TOP1;PPARA;PPARG GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0042493| response to drug PTGS2;TOP1;PPARG 33645:[DB05630 DB02377] DB05630|Sodium stibogluconate TOP1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0042493| response to drug PNP;TOP1 33646:[DB05630 DB12305] DB05630|Sodium stibogluconate TOP1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug TOP1;SLC6A4;SLC6A2;SLC6A3 33647:[DB05630 DB01209] DB05630|Sodium stibogluconate TOP1 DB01209|Dezocine OPRM1;OPRK1 common genes common pathways 33648:[DB05630 DB01174] DB05630|Sodium stibogluconate TOP1 DB01174|Phenobarbital GABRA1;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP2C19;CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2;CYP2A6;CYP2E1;CYP3A5;CYP4A11;CYP1A1;CYP1B1;CYP2C18;CYP3A7;CYP4B1;UGT1A1;UGT2B7;ABCB1;ABCC3;ABCB11;ABCC1;SLCO2A1;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;CYP2E1;GRIN2A;ABCC1;UGT1A1;CYP1A1;ABCB1;ABCC2 33649:[DB05630 DB08992] DB05630|Sodium stibogluconate TOP1 DB08992|Eperisone CYP3A4 common genes common pathways 33650:[DB05630 DB12752] DB05630|Sodium stibogluconate TOP1 DB12752|Bucindolol CYP2D6 common genes common pathways 33651:[DB05630 DB11251] DB05630|Sodium stibogluconate TOP1 DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0016032| viral reproduction LDLR;TOP1;SCARB1 33652:[DB05630 DB00973] DB05630|Sodium stibogluconate TOP1 DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;ABCG5;ABCG8;NPC1L1;ABCG2;ABCC2;UGT1A1;TOP1 GO:0016032| viral reproduction ANPEP;TOP1 33653:[DB05630 DB01577] DB05630|Sodium stibogluconate TOP1 DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug SLC6A3;SLC6A2;MAOB;SLC6A4;TOP1 33654:[DB05630 DB04153] DB05630|Sodium stibogluconate TOP1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways 33655:[DB05630 DB09330] DB05630|Sodium stibogluconate TOP1 DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;TOP1;CYP1A2 GO:0007623| circadian rhythm TOP1;EGFR GO:0016310| phosphorylation TOP1;EGFR 33656:[DB05630 DB00051] DB05630|Sodium stibogluconate TOP1 DB00051|Adalimumab TNF common genes common pathways 33657:[DB05630 DB05740] DB05630|Sodium stibogluconate TOP1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways 33658:[DB05630 DB00451] DB05630|Sodium stibogluconate TOP1 DB00451|Levothyroxine THRA;THRB;CYP2C8;UGT1A1;TTR;SERPINA7;ALB;SLCO1C1;SLC16A2;ABCB1;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4A1;SLCO4C1;SLC7A5;SLCO2B1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;TOP1 33659:[DB05630 DB03756] DB05630|Sodium stibogluconate TOP1 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0007623| circadian rhythm SREBF1;TOP1 GO:0042493| response to drug PPARG;SREBF1;TOP1 GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0048511| rhythmic process PPARA;TOP1;PPARG GO:0016032| viral reproduction TOP1;RXRA 33660:[DB05630 DB06362] DB05630|Sodium stibogluconate TOP1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP2B;TOP1;TOP2A GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP2B;TOP1;TOP2A GO:0048511| rhythmic process TOP1;TOP2A 33661:[DB05630 DB03052] DB05630|Sodium stibogluconate TOP1 DB03052|Dazoxiben TBXAS1 common genes common pathways 33662:[DB05630 DB01024] DB05630|Sodium stibogluconate TOP1 DB01024|Mycophenolic acid IMPDH1;IMPDH2;UGT1A1;UGT1A9;UGT2B7;UGT1A7;UGT1A6 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1 GO:0007623| circadian rhythm IMPDH2;TOP1 33663:[DB05630 DB00473] DB05630|Sodium stibogluconate TOP1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 33664:[DB05630 DB00441] DB05630|Sodium stibogluconate TOP1 DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0016310| phosphorylation TOP1;CMPK1;DCK GO:0006260| DNA replication TOP1;RRM1 GO:0042493| response to drug ABCB1;TYMS;TOP1 GO:0007623| circadian rhythm TYMS;TOP1 33665:[DB05630 DB01046] DB05630|Sodium stibogluconate TOP1 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways 33666:[DB05630 DB03147] DB05630|Sodium stibogluconate TOP1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0016032| viral reproduction TPR;TOP1 GO:0007623| circadian rhythm TOP1;NDUFA9 GO:0042493| response to drug POR;MAOB;TOP1 GO:0016925| protein sumoylation TPR;TOP1 33667:[DB05630 DB00235] DB05630|Sodium stibogluconate TOP1 DB00235|Milrinone PDE3A common genes common pathways GO:0042493| response to drug TOP1;PDE3A 33668:[DB05630 DB00540] DB05630|Sodium stibogluconate TOP1 DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug SLC6A2;HTR2C;ADRA1A;DRD2;HTR2A;CYP2E1;TOP1;CYP1A2;SLC6A4 GO:0007623| circadian rhythm TOP1;SLC6A4 33669:[DB05630 DB05015] DB05630|Sodium stibogluconate TOP1 DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0007623| circadian rhythm TOP1;HDAC3 GO:0032922| circadian regulation of gene expression HDAC1;TOP1;HDAC2 GO:0016925| protein sumoylation HDAC7;TOP1 GO:0042493| response to drug ABCB1;HDAC4;HDAC1;HDAC5;HDAC2;CYP1A2;TOP1 GO:0006338| chromatin remodeling HDAC5;HDAC2;TOP1;HDAC4;HDAC1 GO:0048511| rhythmic process TOP1;HDAC2;HDAC1 GO:0016032| viral reproduction TOP1;HDAC1 33670:[DB05630 DB01396] DB05630|Sodium stibogluconate TOP1 DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1;ABCB1 33671:[DB05630 DB01390] DB05630|Sodium stibogluconate TOP1 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways 33672:[DB05630 DB06717] DB05630|Sodium stibogluconate TOP1 DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways 33673:[DB05630 DB03619] DB05630|Sodium stibogluconate TOP1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction SLC10A1;TOP1 33674:[DB05630 DB00404] DB05630|Sodium stibogluconate TOP1 DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 33675:[DB05630 DB01407] DB05630|Sodium stibogluconate TOP1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1 33676:[DB05630 DB01439] DB05630|Sodium stibogluconate TOP1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 33677:[DB05630 DB00072] DB05630|Sodium stibogluconate TOP1 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0007623| circadian rhythm TOP1;EGFR GO:0016032| viral reproduction TOP1;FCGR2B GO:0016310| phosphorylation EGFR;ERBB2;TOP1 33678:[DB05630 DB00959] DB05630|Sodium stibogluconate TOP1 DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0007059| chromosome segregation TOP1;NR3C1 33679:[DB05630 DB01411] DB05630|Sodium stibogluconate TOP1 DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;ABCC2 33680:[DB05630 DB00041] DB05630|Sodium stibogluconate TOP1 DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0042493| response to drug PTGS2;TOP1;CYP2E1 GO:0016032| viral reproduction IL2RB;TOP1;IL2RG 33681:[DB05630 DB13146] DB05630|Sodium stibogluconate TOP1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0016032| viral reproduction TOP1;SLC1A5 GO:0042493| response to drug ABCB1;TOP1;ABCC4;GRIN2A 33682:[DB05630 DB09555] DB05630|Sodium stibogluconate TOP1 DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways 33683:[DB05630 DB01429] DB05630|Sodium stibogluconate TOP1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways 33684:[DB05630 DB09338] DB05630|Sodium stibogluconate TOP1 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0042493| response to drug TOP1;AQP1 33685:[DB05630 DB00379] DB05630|Sodium stibogluconate TOP1 DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0048511| rhythmic process AHR;TOP1 GO:0032922| circadian regulation of gene expression AHR;TOP1 GO:0042493| response to drug CYP2E1;CYP1A2;TOP1 33686:[DB05630 DB09418] DB05630|Sodium stibogluconate TOP1 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways 33687:[DB05630 DB00526] DB05630|Sodium stibogluconate TOP1 DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0042493| response to drug CYP2E1;SOD1;TOP1;CYP1A1;ABCG2;ABCC2 33688:[DB05630 DB05254] DB05630|Sodium stibogluconate TOP1 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways GO:0007623| circadian rhythm SERPINE1;TOP1 33689:[DB05630 DB01127] DB05630|Sodium stibogluconate TOP1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 33690:[DB05630 DB12952] DB05630|Sodium stibogluconate TOP1 DB12952|Methylprednisone CYP3A4 common genes common pathways 33691:[DB05630 DB02552] DB05630|Sodium stibogluconate TOP1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0016032| viral reproduction FDPS;TOP1 33692:[DB05630 DB08699] DB05630|Sodium stibogluconate TOP1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways GO:0018105| peptidyl-serine phosphorylation CAMK2G;TOP1 GO:0016310| phosphorylation CAMK2G;TOP1 33693:[DB05630 DB00380] DB05630|Sodium stibogluconate TOP1 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP2A;TOP1;TOP2B GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP1;TOP2B;TOP2A 33694:[DB05630 DB03800] DB05630|Sodium stibogluconate TOP1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways GO:0042493| response to drug TYMS;TOP1 GO:0007623| circadian rhythm TOP1;TYMS 33695:[DB05630 DB06243] DB05630|Sodium stibogluconate TOP1 DB06243|Eflornithine ODC1 common genes common pathways 33696:[DB05630 DB00195] DB05630|Sodium stibogluconate TOP1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33697:[DB05630 DB04789] DB05630|Sodium stibogluconate TOP1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0042493| response to drug ABCC2;TOP1 33698:[DB05630 DB09288] DB05630|Sodium stibogluconate TOP1 DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes common pathways GO:0042493| response to drug PTGS2;CYP1A2;TOP1;CYP2E1;BCHE;UGT1A1 33699:[DB05630 DB01363] DB05630|Sodium stibogluconate TOP1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug SLC6A3;SLC6A2;MAOB;SLC6A4;TOP1 33700:[DB05630 DB00499] DB05630|Sodium stibogluconate TOP1 DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0048511| rhythmic process TOP1;AHR GO:0042493| response to drug TOP1;CYP1A2;CYP1A1 GO:0032922| circadian regulation of gene expression TOP1;AHR 33701:[DB05630 DB14540] DB05630|Sodium stibogluconate TOP1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;HSD11B2;ANXA1;ABCG2 GO:0007059| chromosome segregation NR3C1;TOP1 33702:[DB05630 DB01369] DB05630|Sodium stibogluconate TOP1 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways 33703:[DB05630 DB00474] DB05630|Sodium stibogluconate TOP1 DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways 33704:[DB05630 DB13953] DB05630|Sodium stibogluconate TOP1 DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0048511| rhythmic process TOP1;NCOA2 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0032922| circadian regulation of gene expression NCOA2;TOP1 GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;BECN1;UGT1A1;CYP1A2;TOP1 GO:0007623| circadian rhythm TOP1;NCOA2 GO:0016032| viral reproduction TOP1;BECN1 33705:[DB05630 DB09291] DB05630|Sodium stibogluconate TOP1 DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;ABCB1 33706:[DB05630 DB01351] DB05630|Sodium stibogluconate TOP1 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways 33707:[DB05630 DB01380] DB05630|Sodium stibogluconate TOP1 DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 33708:[DB05630 DB00435] DB05630|Sodium stibogluconate TOP1 DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33709:[DB05630 DB13872] DB05630|Sodium stibogluconate TOP1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways 33710:[DB05630 DB14503] DB05630|Sodium stibogluconate TOP1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction TOP1;SLC20A2 GO:0042493| response to drug SLC34A1;TOP1 33711:[DB05630 DB06190] DB05630|Sodium stibogluconate TOP1 DB06190|Solabegron ADRB3 common genes common pathways 33712:[DB05630 DB06787] DB05630|Sodium stibogluconate TOP1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 33713:[DB05630 DB06652] DB05630|Sodium stibogluconate TOP1 DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0016032| viral reproduction TOP1;CCR5 33714:[DB05630 DB06412] DB05630|Sodium stibogluconate TOP1 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0042493| response to drug TOP1;SRD5A1 33715:[DB05630 DB01228] DB05630|Sodium stibogluconate TOP1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways 33716:[DB05630 DB00604] DB05630|Sodium stibogluconate TOP1 DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0042493| response to drug TOP1;HTR2A 33717:[DB05630 DB08901] DB05630|Sodium stibogluconate TOP1 DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;LCK;LYN;SRC;RET;TOP1 GO:0016310| phosphorylation FGFR3;LYN;TEK;LCK;KDR;PDGFRA;ABL1;FGFR4;TOP1;FGFR1;FLT3;BCR;SRC;RET;KIT;FGFR2 GO:0016032| viral reproduction LYN;LCK;KDR;PDGFRA;TOP1;SRC GO:0018105| peptidyl-serine phosphorylation SRC;TOP1 33718:[DB05630 DB11581] DB05630|Sodium stibogluconate TOP1 DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;BCL2;TOP1 GO:0018105| peptidyl-serine phosphorylation BCL2;TOP1 33719:[DB05630 DB01138] DB05630|Sodium stibogluconate TOP1 DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0042493| response to drug ABCC2;ABCC6;ABCC1;SLC22A12;ABCC4;TOP1 33720:[DB05630 DB06713] DB05630|Sodium stibogluconate TOP1 DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways 33721:[DB05630 DB00637] DB05630|Sodium stibogluconate TOP1 DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33722:[DB05630 DB01252] DB05630|Sodium stibogluconate TOP1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0048511| rhythmic process TOP1;PPARG GO:0042493| response to drug PPARG;TOP1;ABCC8 33723:[DB05630 DB00814] DB05630|Sodium stibogluconate TOP1 DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways GO:0042493| response to drug PTGS2;TOP1;ABCC4 33724:[DB05630 DB06262] DB05630|Sodium stibogluconate TOP1 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0042493| response to drug ADRA1A;SLC6A2;TOP1 GO:0007623| circadian rhythm TOP1;DDC 33725:[DB05630 DB01254] DB05630|Sodium stibogluconate TOP1 DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;SRC;PPAT;LYN;CYP1A1;FYN;LCK;ABCB1;ABCG2 GO:0016032| viral reproduction EPHA2;LYN;FYN;HSPA8;LCK;TOP1;SRC GO:0018105| peptidyl-serine phosphorylation MAPK14;SRC;TOP1 GO:0016310| phosphorylation EPHA5;LCK;ABL1;YES1;CSK;FRK;PDGFRB;MAPK14;FYN;EPHB4;EPHA2;LYN;SRC;BCR;KIT;BTK;TOP1;FGR;ABL2 33726:[DB05630 DB01059] DB05630|Sodium stibogluconate TOP1 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;CYP1A1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0007059| chromosome segregation TOP2A;TOP1 GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP1 33727:[DB05630 DB05303] DB05630|Sodium stibogluconate TOP1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways 33728:[DB05630 DB00002] DB05630|Sodium stibogluconate TOP1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007623| circadian rhythm EGFR;TOP1 GO:0016310| phosphorylation TOP1;EGFR GO:0016032| viral reproduction TOP1;FCGR2B 33729:[DB05630 DB02701] DB05630|Sodium stibogluconate TOP1 DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1;LDHA 33730:[DB05630 DB00338] DB05630|Sodium stibogluconate TOP1 DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;AHR GO:0042493| response to drug CYP1A1;ABCB1;ABCG2;TOP1;CYP1A2 GO:0048511| rhythmic process TOP1;AHR 33731:[DB05630 DB09146] DB05630|Sodium stibogluconate TOP1 DB09146|Iron saccharate HBA1;TF common genes common pathways 33732:[DB05630 DB09449] DB05630|Sodium stibogluconate TOP1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction TOP1;SLC20A2 GO:0042493| response to drug TOP1;SLC34A1 33733:[DB05630 DB00533] DB05630|Sodium stibogluconate TOP1 DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0042493| response to drug ABCC4;CYP1A2;PTGS2;TOP1 33734:[DB05630 DB00083] DB05630|Sodium stibogluconate TOP1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 33735:[DB05630 DB13269] DB05630|Sodium stibogluconate TOP1 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0042493| response to drug TOP1;SCN11A 33736:[DB05630 DB06772] DB05630|Sodium stibogluconate TOP1 DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;ABCG2 33737:[DB05630 DB13775] DB05630|Sodium stibogluconate TOP1 DB13775|Tertatolol CYP2D6 common genes common pathways 33738:[DB05630 DB09200] DB05630|Sodium stibogluconate TOP1 DB09200|Rivoglitazone CYP3A4;CYP2C8 common genes common pathways 33739:[DB05630 DB13950] DB05630|Sodium stibogluconate TOP1 DB13950|WIN 55212-2 CYP3A4 common genes common pathways 33740:[DB05630 DB01395] DB05630|Sodium stibogluconate TOP1 DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways GO:0042493| response to drug BCHE;TOP1;PTGS2 33741:[DB05630 DB01126] DB05630|Sodium stibogluconate TOP1 DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0042493| response to drug SRD5A1;SRD5A2;TOP1 33742:[DB05630 DB06370] DB05630|Sodium stibogluconate TOP1 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 33743:[DB05630 DB13866] DB05630|Sodium stibogluconate TOP1 DB13866|Etynodiol CYP3A4 common genes common pathways 33744:[DB05630 DB11348] DB05630|Sodium stibogluconate TOP1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0016032| viral reproduction SLC20A2;TOP1 GO:0042493| response to drug CALR;TOP1;SLC34A1;SLC8A1 33745:[DB05630 DB09389] DB05630|Sodium stibogluconate TOP1 DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0042493| response to drug SRD5A1;TOP1 33746:[DB05630 DB12191] DB05630|Sodium stibogluconate TOP1 DB12191|Obatoclax BCL2 common genes common pathways GO:0018105| peptidyl-serine phosphorylation BCL2;TOP1 GO:0042493| response to drug BCL2;TOP1 33747:[DB05630 DB08807] DB05630|Sodium stibogluconate TOP1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0042493| response to drug TOP1;HTR1B 33748:[DB05630 DB11130] DB05630|Sodium stibogluconate TOP1 DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0042493| response to drug B2M;TOP1 33749:[DB05630 DB06734] DB05630|Sodium stibogluconate TOP1 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 33750:[DB05630 DB00589] DB05630|Sodium stibogluconate TOP1 DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2A;TOP1;DRD1;DRD3;HTR2B;HTR2C;DRD2;HTR1B GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0007623| circadian rhythm TOP1;HTR7 GO:0048511| rhythmic process TOP1;DRD4 GO:0016032| viral reproduction HTR2A;TOP1 GO:0016310| phosphorylation TOP1;HTR2B 33751:[DB05630 DB09502] DB05630|Sodium stibogluconate TOP1 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0016310| phosphorylation HK1;TOP1 33752:[DB05630 DB05505] DB05630|Sodium stibogluconate TOP1 DB05505|NM-702 TBXAS1 common genes common pathways 33753:[DB05630 DB01200] DB05630|Sodium stibogluconate TOP1 DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0016310| phosphorylation TOP1;HTR2B GO:0007623| circadian rhythm HTR7;TOP1 GO:0042493| response to drug TOP1;HTR2A;DRD1;DRD3;HTR1B;ABCB1;DRD2;ADRA1A;HTR2C;HTR2B GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 GO:0048511| rhythmic process DRD4;TOP1 33754:[DB05630 DB01240] DB05630|Sodium stibogluconate TOP1 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways 33755:[DB05630 DB11607] DB05630|Sodium stibogluconate TOP1 DB11607|Efmoroctocog alfa VWF common genes common pathways 33756:[DB05630 DB05039] DB05630|Sodium stibogluconate TOP1 DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1;TOP1 33757:[DB05630 DB04825] DB05630|Sodium stibogluconate TOP1 DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0018105| peptidyl-serine phosphorylation MYLK2;TOP1 GO:0016310| phosphorylation MYLK2;TOP1 33758:[DB05630 DB04964] DB05630|Sodium stibogluconate TOP1 DB04964|Oregovomab MUC16 common genes common pathways 33759:[DB05630 DB05476] DB05630|Sodium stibogluconate TOP1 DB05476|WX-UK1 PLAUR common genes common pathways 33760:[DB05630 DB09029] DB05630|Sodium stibogluconate TOP1 DB09029|Secukinumab IL17A common genes common pathways 33761:[DB05630 DB00836] DB05630|Sodium stibogluconate TOP1 DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33762:[DB05630 DB00210] DB05630|Sodium stibogluconate TOP1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 GO:0016032| viral reproduction RXRA;TOP1 33763:[DB05630 DB12332] DB05630|Sodium stibogluconate TOP1 DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;ABCC4;TOP1;CYP1A2 33764:[DB05630 DB01155] DB05630|Sodium stibogluconate TOP1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33765:[DB05630 DB05431] DB05630|Sodium stibogluconate TOP1 DB05431|MLN-977 ALOX5 common genes common pathways 33766:[DB05630 DB02998] DB05630|Sodium stibogluconate TOP1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0007623| circadian rhythm NCOA2;TOP1 GO:0032922| circadian regulation of gene expression TOP1;NCOA2 GO:0048511| rhythmic process TOP1;NCOA2 33767:[DB05630 DB14635] DB05630|Sodium stibogluconate TOP1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;PPARG;TOP1;CYP1A2 GO:0048511| rhythmic process PPARG;TOP1 33768:[DB05630 DB00877] DB05630|Sodium stibogluconate TOP1 DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0016310| phosphorylation MTOR;TOP1 GO:0018105| peptidyl-serine phosphorylation MTOR;TOP1 GO:0042493| response to drug TOP1;ABCB1 33769:[DB05630 DB11712] DB05630|Sodium stibogluconate TOP1 DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways 33770:[DB05630 DB02813] DB05630|Sodium stibogluconate TOP1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways 33771:[DB05630 DB12334] DB05630|Sodium stibogluconate TOP1 DB12334|Milataxel TUBB1;TUBB common genes common pathways 33772:[DB05630 DB07462] DB05630|Sodium stibogluconate TOP1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0042493| response to drug TOP1;COMT 33773:[DB05630 DB09303] DB05630|Sodium stibogluconate TOP1 DB09303|Evolocumab PCSK9 common genes common pathways 33774:[DB05630 DB06212] DB05630|Sodium stibogluconate TOP1 DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33775:[DB05630 DB00438] DB05630|Sodium stibogluconate TOP1 DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 33776:[DB05630 DB05668] DB05630|Sodium stibogluconate TOP1 DB05668|Palifosfamide DNMT1 common genes common pathways 33777:[DB05630 DB03403] DB05630|Sodium stibogluconate TOP1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways GO:0016310| phosphorylation UCK2;TOP1;CMPK1 33778:[DB05630 DB00685] DB05630|Sodium stibogluconate TOP1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP1 GO:0042493| response to drug CYP1A2;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0007059| chromosome segregation TOP2A;TOP1 GO:0048511| rhythmic process TOP1;TOP2A 33779:[DB05630 DB06237] DB05630|Sodium stibogluconate TOP1 DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways 33780:[DB05630 DB04074] DB05630|Sodium stibogluconate TOP1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 33781:[DB05630 DB01102] DB05630|Sodium stibogluconate TOP1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways 33782:[DB05630 DB04843] DB05630|Sodium stibogluconate TOP1 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways 33783:[DB05630 DB11703] DB05630|Sodium stibogluconate TOP1 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0016310| phosphorylation TOP1;BTK 33784:[DB05630 DB00655] DB05630|Sodium stibogluconate TOP1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0042493| response to drug CYP2E1;TOP1;CYP1A2;ABCG2;ABCB1;CYP1A1 33785:[DB05630 DB00696] DB05630|Sodium stibogluconate TOP1 DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug DRD1;TOP1;HTR2A;HTR1B;ABCB1;ADRA1A;DRD2;HTR2B;HTR2C;SLC6A2 GO:0016310| phosphorylation TOP1;HTR2B GO:0016032| viral reproduction TOP1;HTR2A 33786:[DB05630 DB05087] DB05630|Sodium stibogluconate TOP1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways 33787:[DB05630 DB04840] DB05630|Sodium stibogluconate TOP1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;CYP1A1;TOP1 33788:[DB05630 DB00886] DB05630|Sodium stibogluconate TOP1 DB00886|Omapatrilat ACE;MME common genes common pathways 33789:[DB05630 DB05351] DB05630|Sodium stibogluconate TOP1 DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways 33790:[DB05630 DB14642] DB05630|Sodium stibogluconate TOP1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0042493| response to drug ABCC2;TOP1 33791:[DB05630 DB00635] DB05630|Sodium stibogluconate TOP1 DB00635|Prednisone NR3C1;HSD11B1;CYP3A4;CYP2C19;ALB;ABCB1;SLCO1A2 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0007059| chromosome segregation NR3C1;TOP1 33792:[DB05630 DB06536] DB05630|Sodium stibogluconate TOP1 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug TOP1;PPARG GO:0048511| rhythmic process TOP1;PPARA;PPARG 33793:[DB05630 DB01219] DB05630|Sodium stibogluconate TOP1 DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways 33794:[DB05630 DB00845] DB05630|Sodium stibogluconate TOP1 DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33795:[DB05630 DB09166] DB05630|Sodium stibogluconate TOP1 DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways 33796:[DB05630 DB12945] DB05630|Sodium stibogluconate TOP1 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33797:[DB05630 DB04889] DB05630|Sodium stibogluconate TOP1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug MAOB;SLC6A2;DRD2;TOP1;SLC6A4 GO:0032922| circadian regulation of gene expression DRD2;TOP1 33798:[DB05630 DB00782] DB05630|Sodium stibogluconate TOP1 DB00782|Propantheline CHRM1 common genes common pathways 33799:[DB05630 DB00422] DB05630|Sodium stibogluconate TOP1 DB00422|Methylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A2;SLC6A3;TOP1;SLC6A4 GO:0007623| circadian rhythm SLC6A4;TOP1 33800:[DB05630 DB14508] DB05630|Sodium stibogluconate TOP1 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;GSK3B GO:0016310| phosphorylation GSK3B;TOP1 GO:0007623| circadian rhythm GSK3B;TOP1 GO:0048511| rhythmic process GSK3B;TOP1 33801:[DB05630 DB04872] DB05630|Sodium stibogluconate TOP1 DB04872|Osanetant TACR3 common genes common pathways 33802:[DB05630 DB00502] DB05630|Sodium stibogluconate TOP1 DB00502|Haloperidol DRD2;DRD1;GRIN2B;HTR2A;DRD3;MCHR1;SLC18A2;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP3A4;CBR1;UGT1A9;CYP1A1;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A1;DRD3;DRD2;ABCB1;CYP1A2;TOP1;HTR2A;DRD1 GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 33803:[DB05630 DB05434] DB05630|Sodium stibogluconate TOP1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways 33804:[DB05630 DB01008] DB05630|Sodium stibogluconate TOP1 DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways 33805:[DB05630 DB06211] DB05630|Sodium stibogluconate TOP1 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways 33806:[DB05630 DB00517] DB05630|Sodium stibogluconate TOP1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways 33807:[DB05630 DB08838] DB05630|Sodium stibogluconate TOP1 DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways 33808:[DB05630 DB00131] DB05630|Sodium stibogluconate TOP1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0042493| response to drug ACSL1;ADCY1;CREB1;TOP1 GO:0007623| circadian rhythm TOP1;CREB1;ADCY1 GO:0048511| rhythmic process TOP1;PRKAA1;ADCY1;CREB1 GO:0016032| viral reproduction CREB1;TOP1 GO:0016310| phosphorylation ADK;TOP1;PIM1;PRKAA1 33809:[DB05630 DB00594] DB05630|Sodium stibogluconate TOP1 DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0042493| response to drug AOC1;TOP1 33810:[DB05630 DB06288] DB05630|Sodium stibogluconate TOP1 DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD3;DRD2 GO:0042493| response to drug DRD3;DRD2;TOP1;HTR2A GO:0007623| circadian rhythm HTR7;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 33811:[DB05630 DB00569] DB05630|Sodium stibogluconate TOP1 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways 33812:[DB05630 DB11358] DB05630|Sodium stibogluconate TOP1 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways 33813:[DB05630 DB09282] DB05630|Sodium stibogluconate TOP1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 33814:[DB05630 DB00630] DB05630|Sodium stibogluconate TOP1 DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways GO:0016032| viral reproduction FDPS;TOP1 33815:[DB05630 DB00237] DB05630|Sodium stibogluconate TOP1 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 33816:[DB05630 DB11094] DB05630|Sodium stibogluconate TOP1 DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways 33817:[DB05630 DB01080] DB05630|Sodium stibogluconate TOP1 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0042493| response to drug ABAT;TOP1 33818:[DB05630 DB05218] DB05630|Sodium stibogluconate TOP1 DB05218|PN0621 TNF common genes common pathways 33819:[DB05630 DB09053] DB05630|Sodium stibogluconate TOP1 DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0016310| phosphorylation BTK;TOP1 33820:[DB05630 DB00276] DB05630|Sodium stibogluconate TOP1 DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0042493| response to drug ABCB1;TOP1 GO:0007059| chromosome segregation TOP2A;TOP1 GO:0048511| rhythmic process TOP2A;TOP1 33821:[DB05630 DB00458] DB05630|Sodium stibogluconate TOP1 DB00458|Imipramine SLC6A2;HTR2A;SLC6A4;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCND2;KCND3;HTR2C;ADRA1B;HTR7;DRD1;DRD5;DRD2;KCNH2;SLC6A3;HTR1A;HTR6;KCNH1;ORM2;CYP2C19;CYP2D6;CYP1A2;CYP3A4;CYP3A7;CYP2B6;CYP2C18;CYP2E1;ORM1;ALB;ABCB1;SLC22A2;SLC22A3;SLC22A4 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0007623| circadian rhythm SLC6A4;TOP1;HTR7 GO:0042493| response to drug TOP1;CYP1A2;HTR2A;CYP2E1;DRD1;SLC6A4;SLC6A2;ADRA1A;DRD2;ABCB1;SLC6A3;HTR2C GO:0032922| circadian regulation of gene expression TOP1;DRD2 33822:[DB05630 DB14018] DB05630|Sodium stibogluconate TOP1 DB14018|Bromotheophylline CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33823:[DB05630 DB00346] DB05630|Sodium stibogluconate TOP1 DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 33824:[DB05630 DB09265] DB05630|Sodium stibogluconate TOP1 DB09265|Lixisenatide GLP1R common genes common pathways 33825:[DB05630 DB11586] DB05630|Sodium stibogluconate TOP1 DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33826:[DB05630 DB00675] DB05630|Sodium stibogluconate TOP1 DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;PRKCE;PRKCB;PRKCI;PRKCZ;PRKCG;PRKCD;PRKCQ;PRKCA GO:0016310| phosphorylation PRKCE;TOP1;PRKCG;PRKCB;PRKCI;PRKCZ;PRKCD;PRKCA;PRKCQ GO:0042493| response to drug ABCB1;ABCC2;ABCG2;CYP1A1;TOP1;CYP2E1 GO:0048511| rhythmic process PRKCG;TOP1 GO:0006338| chromatin remodeling TOP1;ESR1 33827:[DB05630 DB14065] DB05630|Sodium stibogluconate TOP1 DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33828:[DB05630 DB01019] DB05630|Sodium stibogluconate TOP1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways 33829:[DB05630 DB13800] DB05630|Sodium stibogluconate TOP1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways 33830:[DB05630 DB08613] DB05630|Sodium stibogluconate TOP1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0006338| chromatin remodeling TOP1;HDAC4 GO:0042493| response to drug HDAC4;TOP1 33831:[DB05630 DB01496] DB05630|Sodium stibogluconate TOP1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 33832:[DB05630 DB04948] DB05630|Sodium stibogluconate TOP1 DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;ADRA1A;HTR2C GO:0007623| circadian rhythm HTR7;TOP1 33833:[DB05630 DB11637] DB05630|Sodium stibogluconate TOP1 DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways 33834:[DB05630 DB13994] DB05630|Sodium stibogluconate TOP1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 33835:[DB05630 DB00414] DB05630|Sodium stibogluconate TOP1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways 33836:[DB05630 DB00565] DB05630|Sodium stibogluconate TOP1 DB00565|Cisatracurium CHRNA2 common genes common pathways 33837:[DB05630 DB08502] DB05630|Sodium stibogluconate TOP1 DB08502|Capravirine CYP3A4 common genes common pathways 33838:[DB05630 DB00494] DB05630|Sodium stibogluconate TOP1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0042493| response to drug COMT;TOP1 33839:[DB05630 DB01548] DB05630|Sodium stibogluconate TOP1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways 33840:[DB05630 DB06148] DB05630|Sodium stibogluconate TOP1 DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1;HTR7 GO:0042493| response to drug TOP1;CYP1A2;HTR2A;DRD1;SLC6A4;SLC6A2;DRD3;ADRA1A;DRD2;SLC6A3;HTR2B;HTR2C GO:0032922| circadian regulation of gene expression TOP1;DRD3;DRD2 GO:0016310| phosphorylation TOP1;HTR2B GO:0016032| viral reproduction HTR2A;TOP1 33841:[DB05630 DB12093] DB05630|Sodium stibogluconate TOP1 DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;TOP1;DRD2 GO:0032922| circadian regulation of gene expression DRD2;TOP1 33842:[DB05630 DB00315] DB05630|Sodium stibogluconate TOP1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0042493| response to drug HTR1B;CYP1A2;TOP1 33843:[DB05630 DB11064] DB05630|Sodium stibogluconate TOP1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 33844:[DB05630 DB07720] DB05630|Sodium stibogluconate TOP1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways 33845:[DB05630 DB05201] DB05630|Sodium stibogluconate TOP1 DB05201|V24343 CNR1 common genes common pathways 33846:[DB05630 DB03566] DB05630|Sodium stibogluconate TOP1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways 33847:[DB05630 DB09331] DB05630|Sodium stibogluconate TOP1 DB09331|Daratumumab CD38 common genes common pathways GO:0042493| response to drug TOP1;CD38 33848:[DB05630 DB06111] DB05630|Sodium stibogluconate TOP1 DB06111|AB192 MPO common genes common pathways 33849:[DB05630 DB01074] DB05630|Sodium stibogluconate TOP1 DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0007623| circadian rhythm TOP1;CPT1A GO:0042493| response to drug TOP1;CPT1A 33850:[DB05630 DB05091] DB05630|Sodium stibogluconate TOP1 DB05091|M0002 AVPR2 common genes common pathways 33851:[DB05630 DB06595] DB05630|Sodium stibogluconate TOP1 DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;CYP2E1 GO:0018105| peptidyl-serine phosphorylation PRKCA;TOP1 GO:0016032| viral reproduction TOP1;KDR;PDGFRA GO:0016310| phosphorylation TOP1;FLT3;KIT;PDGFRB;KDR;PDGFRA;PRKCA 33852:[DB05630 DB00790] DB05630|Sodium stibogluconate TOP1 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug BCHE;TOP1 33853:[DB05630 DB01296] DB05630|Sodium stibogluconate TOP1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0048511| rhythmic process TOP1;NFKB2 GO:0042493| response to drug CYP2E1;TOP1 33854:[DB05630 DB12866] DB05630|Sodium stibogluconate TOP1 DB12866|Pradigastat SLC22A8 common genes common pathways 33855:[DB05630 DB00849] DB05630|Sodium stibogluconate TOP1 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways 33856:[DB05630 DB01412] DB05630|Sodium stibogluconate TOP1 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;CYP2E1;ADORA2A 33857:[DB05630 DB04674] DB05630|Sodium stibogluconate TOP1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways 33858:[DB05630 DB04827] DB05630|Sodium stibogluconate TOP1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways 33859:[DB05630 DB00521] DB05630|Sodium stibogluconate TOP1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways 33860:[DB05630 DB00549] DB05630|Sodium stibogluconate TOP1 DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;TOP1;CYP1A2;CYP2E1 33861:[DB05630 DB00531] DB05630|Sodium stibogluconate TOP1 DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways 33862:[DB05630 DB05419] DB05630|Sodium stibogluconate TOP1 DB05419|ADX-10061 CALY common genes common pathways 33863:[DB05630 DB06700] DB05630|Sodium stibogluconate TOP1 DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0042493| response to drug SLC6A4;TOP1;SLC6A2 GO:0007623| circadian rhythm TOP1;SLC6A4 33864:[DB05630 DB00852] DB05630|Sodium stibogluconate TOP1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0007623| circadian rhythm JUN;TOP1;ATF4;SLC6A4;ATF5 GO:0042493| response to drug SLC6A4;JUN;TOP1;SLC6A3;ADRA1A;FOS;SLC6A2 GO:0032922| circadian regulation of gene expression TOP1;ATF4 GO:0048511| rhythmic process TOP1;ATF4 GO:0016032| viral reproduction TOP1;ATF7 33865:[DB05630 DB06769] DB05630|Sodium stibogluconate TOP1 DB06769|Bendamustine CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33866:[DB05630 DB05022] DB05630|Sodium stibogluconate TOP1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP1;TOP2B;TOP2A GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP2B;TOP1 33867:[DB05630 DB00192] DB05630|Sodium stibogluconate TOP1 DB00192|Indecainide SCN5A common genes common pathways 33868:[DB05630 DB00534] DB05630|Sodium stibogluconate TOP1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways 33869:[DB05630 DB00229] DB05630|Sodium stibogluconate TOP1 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways 33870:[DB05630 DB05210] DB05630|Sodium stibogluconate TOP1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0048511| rhythmic process TOP1;PRKDC GO:0016310| phosphorylation PRKDC;TOP1;MTOR GO:0018105| peptidyl-serine phosphorylation MTOR;PRKDC;TOP1 GO:0016032| viral reproduction PIK3R1;TOP1 33871:[DB05630 DB01588] DB05630|Sodium stibogluconate TOP1 DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 33872:[DB05630 DB00963] DB05630|Sodium stibogluconate TOP1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 33873:[DB05630 DB00396] DB05630|Sodium stibogluconate TOP1 DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0016032| viral reproduction SLC10A1;TOP1 GO:0007059| chromosome segregation TOP1;NR3C1 GO:0042493| response to drug ABCG2;ABCB1;CYP1A1;ABCC1;TOP1 GO:0006338| chromatin remodeling TOP1;ESR1 33874:[DB05630 DB06138] DB05630|Sodium stibogluconate TOP1 DB06138|IRL-1620 EDNRB common genes common pathways 33875:[DB05630 DB00289] DB05630|Sodium stibogluconate TOP1 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug SLC6A4;GRIN2A;TOP1;SLC6A3;SLC6A2 GO:0007623| circadian rhythm TOP1;SLC6A4 33876:[DB05630 DB00946] DB05630|Sodium stibogluconate TOP1 DB00946|Phenprocoumon VKORC1;CYP2C8;CYP2C9;CYP3A4;ALB;ORM1 common genes common pathways 33877:[DB05630 DB11491] DB05630|Sodium stibogluconate TOP1 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33878:[DB05630 DB06751] DB05630|Sodium stibogluconate TOP1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways 33879:[DB05630 DB04926] DB05630|Sodium stibogluconate TOP1 DB04926|Neramexane GRIN3A common genes common pathways 33880:[DB05630 DB01650] DB05630|Sodium stibogluconate TOP1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways 33881:[DB05630 DB01257] DB05630|Sodium stibogluconate TOP1 DB01257|Eculizumab C5 common genes common pathways 33882:[DB05630 DB00150] DB05630|Sodium stibogluconate TOP1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0007623| circadian rhythm TPH1;TPH2;DDC;TOP1 33883:[DB05630 DB12035] DB05630|Sodium stibogluconate TOP1 DB12035|Sarecycline ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33884:[DB05630 DB11577] DB05630|Sodium stibogluconate TOP1 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0048511| rhythmic process TOP1;AHR GO:0032922| circadian regulation of gene expression TOP1;AHR GO:0042493| response to drug TOP1;ADRA1A 33885:[DB05630 DB01288] DB05630|Sodium stibogluconate TOP1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways 33886:[DB05630 DB08827] DB05630|Sodium stibogluconate TOP1 DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33887:[DB05630 DB06155] DB05630|Sodium stibogluconate TOP1 DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways 33888:[DB05630 DB06274] DB05630|Sodium stibogluconate TOP1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways 33889:[DB05630 DB11431] DB05630|Sodium stibogluconate TOP1 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;TOP1 33890:[DB05630 DB06292] DB05630|Sodium stibogluconate TOP1 DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;ABCB1;CYP1A1 33891:[DB05630 DB00715] DB05630|Sodium stibogluconate TOP1 DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug SLC6A4;TOP1;CYP1A2;HTR2A;ABCB1;SLC6A2 33892:[DB05630 DB05688] DB05630|Sodium stibogluconate TOP1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0042493| response to drug SLC6A2;SLC6A4;TOP1 GO:0007623| circadian rhythm TOP1;SLC6A4 33893:[DB05630 DB00567] DB05630|Sodium stibogluconate TOP1 DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways 33894:[DB05630 DB04958] DB05630|Sodium stibogluconate TOP1 DB04958|Epratuzumab CD22 common genes common pathways 33895:[DB05630 DB01483] DB05630|Sodium stibogluconate TOP1 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways 33896:[DB05630 DB00130] DB05630|Sodium stibogluconate TOP1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0016032| viral reproduction SLC1A5;TOP1 GO:0042493| response to drug PFAS;CTPS1;PPAT;TOP1 33897:[DB05630 DB06579] DB05630|Sodium stibogluconate TOP1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 33898:[DB05630 DB00834] DB05630|Sodium stibogluconate TOP1 DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;ABCC1;ABCB1 GO:0007059| chromosome segregation NR3C1;TOP1 33899:[DB05630 DB14069] DB05630|Sodium stibogluconate TOP1 DB14069|ONT-093 ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33900:[DB05630 DB01551] DB05630|Sodium stibogluconate TOP1 DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways 33901:[DB05630 DB00978] DB05630|Sodium stibogluconate TOP1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0006265| DNA topological change TOP1;TOP2A GO:0040016| embryonic cleavage TOP1;TOP2A GO:0048511| rhythmic process TOP1;TOP2A GO:0007059| chromosome segregation TOP2A;TOP1 GO:0042493| response to drug TOP1;CYP1A2;ABCC2 GO:0016925| protein sumoylation TOP1;TOP2A 33902:[DB05630 DB06714] DB05630|Sodium stibogluconate TOP1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways 33903:[DB05630 DB05034] DB05630|Sodium stibogluconate TOP1 DB05034|Ularitide NPR1 common genes common pathways 33904:[DB05630 DB06603] DB05630|Sodium stibogluconate TOP1 DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0016032| viral reproduction TOP1;HDAC1 GO:0007623| circadian rhythm HDAC3;TOP1 GO:0032922| circadian regulation of gene expression TOP1;HDAC2;HDAC1 GO:0016925| protein sumoylation TOP1;HDAC7 GO:0042493| response to drug ABCB1;HDAC1;HDAC4;HDAC2;HDAC5;TOP1 GO:0006338| chromatin remodeling HDAC5;HDAC2;TOP1;HDAC4;HDAC1 GO:0048511| rhythmic process HDAC1;HDAC2;TOP1 33905:[DB05630 DB09030] DB05630|Sodium stibogluconate TOP1 DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways 33906:[DB05630 DB06342] DB05630|Sodium stibogluconate TOP1 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways 33907:[DB05630 DB04299] DB05630|Sodium stibogluconate TOP1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0016032| viral reproduction TOP1;TPR GO:0016925| protein sumoylation TPR;TOP1 33908:[DB05630 DB00529] DB05630|Sodium stibogluconate TOP1 DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways 33909:[DB05630 DB07194] DB05630|Sodium stibogluconate TOP1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways GO:0016310| phosphorylation TOP1;SYK GO:0018105| peptidyl-serine phosphorylation SYK;TOP1 GO:0016032| viral reproduction SYK;TOP1 33910:[DB05630 DB09108] DB05630|Sodium stibogluconate TOP1 DB09108|Simoctocog Alfa VWF common genes common pathways 33911:[DB05630 DB00537] DB05630|Sodium stibogluconate TOP1 DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0016925| protein sumoylation TOP2A;TOP1 GO:0042493| response to drug ABCB1;CYP1A2;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP1 33912:[DB05630 DB00713] DB05630|Sodium stibogluconate TOP1 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways 33913:[DB05630 DB14055] DB05630|Sodium stibogluconate TOP1 DB14055|(S)-Warfarin CYP3A4;CYP2C8;CYP2C9;CYP2C18;CYP2C19 common genes common pathways 33914:[DB05630 DB00305] DB05630|Sodium stibogluconate TOP1 DB00305|Mitomycin POR common genes common pathways GO:0042493| response to drug TOP1;POR 33915:[DB05630 DB09195] DB05630|Sodium stibogluconate TOP1 DB09195|Lorpiprazole HTR2A;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;SLC6A4;CYP2D6;CYP3A4;ALB common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug ADRA1A;HTR2C;TOP1;HTR2A;SLC6A4 33916:[DB05630 DB01047] DB05630|Sodium stibogluconate TOP1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 33917:[DB05630 DB00501] DB05630|Sodium stibogluconate TOP1 DB00501|Cimetidine HRH2;CYP1A2;CYP2C19;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP11B1;CYP2C8;CYP2C9;CYP2E1;FMO3;FMO1;ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A6;SLC22A8;SLC47A1;SLC22A4;SLC22A11;SLC22A7;ABCB11;SLC47A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1;CYP1A2;TOP1 33918:[DB05630 DB00619] DB05630|Sodium stibogluconate TOP1 DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0016310| phosphorylation PDGFRB;NTRK1;DDR1;ABL1;PDGFRA;TOP1;RET;CSF1R;KIT GO:0016032| viral reproduction PDGFRA;TOP1 GO:0007623| circadian rhythm TOP1;NTRK1 GO:0042493| response to drug NTRK1;ABCB1;ABCG2;TOP1;ABCA3;CYP1A2;RET 33919:[DB05630 DB01263] DB05630|Sodium stibogluconate TOP1 DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33920:[DB05630 DB08904] DB05630|Sodium stibogluconate TOP1 DB08904|Certolizumab pegol TNF common genes common pathways 33921:[DB05630 DB08882] DB05630|Sodium stibogluconate TOP1 DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33922:[DB05630 DB08900] DB05630|Sodium stibogluconate TOP1 DB08900|Teduglutide GLP2R common genes common pathways 33923:[DB05630 DB13167] DB05630|Sodium stibogluconate TOP1 DB13167|Alclofenac PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 33924:[DB05630 DB00182] DB05630|Sodium stibogluconate TOP1 DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0042493| response to drug SLC6A3;ADRA1A;DRD2;MAOB;SLC6A2;SLC6A4;TOP1 GO:0032922| circadian regulation of gene expression DRD2;CARTPT;TOP1 GO:0007623| circadian rhythm SLC6A4;TOP1 33925:[DB05630 DB00921] DB05630|Sodium stibogluconate TOP1 DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;ABCB1;UGT1A1 33926:[DB05630 DB01590] DB05630|Sodium stibogluconate TOP1 DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;MTOR GO:0016310| phosphorylation MTOR;TOP1 33927:[DB05630 DB00661] DB05630|Sodium stibogluconate TOP1 DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A;ABCB1;ABCG2;ABCC2;CYP1A2;TOP1;KCNJ11;ABCC4;SLC6A4 GO:0007623| circadian rhythm TOP1;SLC6A4 33928:[DB05630 DB01367] DB05630|Sodium stibogluconate TOP1 DB01367|Rasagiline MAOB;BCL2;CYP1A2 common genes common pathways GO:0042493| response to drug MAOB;TOP1;BCL2;CYP1A2 GO:0018105| peptidyl-serine phosphorylation TOP1;BCL2 33929:[DB05630 DB01307] DB05630|Sodium stibogluconate TOP1 DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0016310| phosphorylation TOP1;INSR 33930:[DB05630 DB01571] DB05630|Sodium stibogluconate TOP1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 33931:[DB05630 DB00353] DB05630|Sodium stibogluconate TOP1 DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;TOP1;HTR2B GO:0016310| phosphorylation HTR2B;TOP1 33932:[DB05630 DB01408] DB05630|Sodium stibogluconate TOP1 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0042493| response to drug BCHE;TOP1 33933:[DB05630 DB08820] DB05630|Sodium stibogluconate TOP1 DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 33934:[DB05630 DB00324] DB05630|Sodium stibogluconate TOP1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 33935:[DB05630 DB04938] DB05630|Sodium stibogluconate TOP1 DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 33936:[DB05630 DB13878] DB05630|Sodium stibogluconate TOP1 DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;UGT1A1;TOP1 33937:[DB05630 DB13961] DB05630|Sodium stibogluconate TOP1 DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0007623| circadian rhythm SREBF1;TOP1 GO:0042493| response to drug TOP1;PTGS2;PPARG;SREBF1 GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0048511| rhythmic process PPARA;TOP1;NFKB2;PPARG 33938:[DB05630 DB00261] DB05630|Sodium stibogluconate TOP1 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;PDE3A 33939:[DB05630 DB00444] DB05630|Sodium stibogluconate TOP1 DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0006265| DNA topological change TOP1;TOP2A GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0048511| rhythmic process TOP2A;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP1;TOP2A GO:0042493| response to drug TOP1;ABCG2;ABCC6 33940:[DB05630 DB01942] DB05630|Sodium stibogluconate TOP1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0016310| phosphorylation CASK;TOP1 GO:0016032| viral reproduction TOP1;CTBP1 33941:[DB05630 DB01098] DB05630|Sodium stibogluconate TOP1 DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways GO:0042493| response to drug ABCC1;ABCG2;ABCC2;TOP1;ABCC4 33942:[DB05630 DB13508] DB05630|Sodium stibogluconate TOP1 DB13508|Cloranolol CYP2D6 common genes common pathways 33943:[DB05630 DB01236] DB05630|Sodium stibogluconate TOP1 DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:0042493| response to drug GABRG3;TOP1;CYP2E1;MT-ND1 33944:[DB05630 DB09481] DB05630|Sodium stibogluconate TOP1 DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0016310| phosphorylation TRPM6;TOP1;TRPM7 GO:0012501| programmed cell death TRPM7;TOP1 GO:0042493| response to drug GRIN2A;TOP1 33945:[DB05630 DB02489] DB05630|Sodium stibogluconate TOP1 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 33946:[DB05630 DB13954] DB05630|Sodium stibogluconate TOP1 DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0032922| circadian regulation of gene expression NCOA2;TOP1 GO:0042493| response to drug CYP1A1;BECN1;UGT1A1;ABCG2;ABCB1;TOP1;CYP1A2 GO:0007623| circadian rhythm NCOA2;TOP1 GO:0048511| rhythmic process TOP1;NCOA2 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0016032| viral reproduction TOP1;BECN1 33947:[DB05630 DB04365] DB05630|Sodium stibogluconate TOP1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways 33948:[DB05630 DB01593] DB05630|Sodium stibogluconate TOP1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0032922| circadian regulation of gene expression HDAC1;TOP1 GO:0042493| response to drug TP73;APOA1;MDM2;TP53;APOA2;HDAC4;HDAC1;NME1;TOP1;MGMT;SOD1 GO:0016925| protein sumoylation MDM2;TOP1 GO:0048511| rhythmic process TP53;HDAC1;TOP1 GO:0012501| programmed cell death TP53;TOP1 GO:0006338| chromatin remodeling ESR1;TOP1;HDAC4;HDAC1 GO:0016032| viral reproduction SIVA1;TOP1;CFH;TP73;TP53;MDM2;APOA2;HDAC1;IDE GO:0016310| phosphorylation NME1;TOP1 33949:[DB05630 DB00075] DB05630|Sodium stibogluconate TOP1 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FCGR2B;CD247;TOP1 33950:[DB05630 DB09063] DB05630|Sodium stibogluconate TOP1 DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0016310| phosphorylation TOP1;ALK 33951:[DB05630 DB00607] DB05630|Sodium stibogluconate TOP1 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 33952:[DB05630 DB05932] DB05630|Sodium stibogluconate TOP1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0016310| phosphorylation FLT4;TOP1;FLT1 33953:[DB05630 DB06786] DB05630|Sodium stibogluconate TOP1 DB06786|Halcinonide SMO;CYP3A4 common genes common pathways 33954:[DB05630 DB00514] DB05630|Sodium stibogluconate TOP1 DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug CYP2E1;TOP1;CYBA;SLC6A4;CYBB;SLC6A2 33955:[DB05630 DB01101] DB05630|Sodium stibogluconate TOP1 DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways GO:0007623| circadian rhythm TYMS;TOP1 GO:0042493| response to drug TOP1;TYMS 33956:[DB05630 DB13141] DB05630|Sodium stibogluconate TOP1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 33957:[DB05630 DB13867] DB05630|Sodium stibogluconate TOP1 DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33958:[DB05630 DB01275] DB05630|Sodium stibogluconate TOP1 DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways 33959:[DB05630 DB12092] DB05630|Sodium stibogluconate TOP1 DB12092|Naftopidil CYP3A4 common genes common pathways 33960:[DB05630 DB00134] DB05630|Sodium stibogluconate TOP1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0042493| response to drug TOP1;MTHFR 33961:[DB05630 DB02943] DB05630|Sodium stibogluconate TOP1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways 33962:[DB05630 DB01327] DB05630|Sodium stibogluconate TOP1 DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0042493| response to drug ABCC4;TOP1 33963:[DB05630 DB07280] DB05630|Sodium stibogluconate TOP1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways GO:0016310| phosphorylation ADK;TOP1 33964:[DB05630 DB00342] DB05630|Sodium stibogluconate TOP1 DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33965:[DB05630 DB00398] DB05630|Sodium stibogluconate TOP1 DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0016032| viral reproduction TOP1;KDR GO:0016310| phosphorylation TOP1;RAF1;FLT1;FLT3;FGFR1;KIT;RET;FLT4;PDGFRB;KDR;BRAF GO:0042493| response to drug UGT1A1;ABCC2;ABCG2;ABCB1;TOP1;CYP1A2;ABCC4;RET 33966:[DB05630 DB13923] DB05630|Sodium stibogluconate TOP1 DB13923|Emicizumab F9;F10 common genes common pathways 33967:[DB05630 DB14061] DB05630|Sodium stibogluconate TOP1 DB14061|Hycanthone ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33968:[DB05630 DB00112] DB05630|Sodium stibogluconate TOP1 DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction TOP1;FCGR2B 33969:[DB05630 DB09034] DB05630|Sodium stibogluconate TOP1 DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways 33970:[DB05630 DB01242] DB05630|Sodium stibogluconate TOP1 DB01242|Clomipramine SLC6A4;HTR2A;HTR2B;HTR2C;SLC6A2;GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;ALB;ABCB1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug TOP1;CYP1A2;HTR2A;SLC6A4;SLC6A2;ABCB1;HTR2C;HTR2B GO:0016032| viral reproduction HTR2A;TOP1 GO:0016310| phosphorylation TOP1;HTR2B 33971:[DB05630 DB06458] DB05630|Sodium stibogluconate TOP1 DB06458|Remacemide CYP3A4 common genes common pathways 33972:[DB05630 DB07840] DB05630|Sodium stibogluconate TOP1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways GO:0016310| phosphorylation FGFR1;TOP1 33973:[DB05630 DB00470] DB05630|Sodium stibogluconate TOP1 DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A1;ABCB1;ABCG2;TOP1 33974:[DB05630 DB01295] DB05630|Sodium stibogluconate TOP1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0042493| response to drug ADRA1A;TOP1 33975:[DB05630 DB01336] DB05630|Sodium stibogluconate TOP1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways 33976:[DB05630 DB06655] DB05630|Sodium stibogluconate TOP1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways 33977:[DB05630 DB04539] DB05630|Sodium stibogluconate TOP1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways 33978:[DB05630 DB00559] DB05630|Sodium stibogluconate TOP1 DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways 33979:[DB05630 DB00823] DB05630|Sodium stibogluconate TOP1 DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 33980:[DB05630 DB05372] DB05630|Sodium stibogluconate TOP1 DB05372|CP-945598 CNR1 common genes common pathways 33981:[DB05630 DB00174] DB05630|Sodium stibogluconate TOP1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0016032| viral reproduction TOP1;SLC1A5 33982:[DB05630 DB01154] DB05630|Sodium stibogluconate TOP1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;KCNJ11;TOP1 33983:[DB05630 DB01356] DB05630|Sodium stibogluconate TOP1 DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:0018105| peptidyl-serine phosphorylation GSK3B;TOP1 GO:0016310| phosphorylation GSK3B;TOP1 GO:0007623| circadian rhythm TOP1;GSK3B GO:0048511| rhythmic process TOP1;GSK3B 33984:[DB05630 DB06779] DB05630|Sodium stibogluconate TOP1 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways 33985:[DB05630 DB05501] DB05630|Sodium stibogluconate TOP1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0016032| viral reproduction TOP1;CXCR4;CCR5 33986:[DB05630 DB06702] DB05630|Sodium stibogluconate TOP1 DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 33987:[DB05630 DB01426] DB05630|Sodium stibogluconate TOP1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways 33988:[DB05630 DB00462] DB05630|Sodium stibogluconate TOP1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways 33989:[DB05630 DB04850] DB05630|Sodium stibogluconate TOP1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways 33990:[DB05630 DB06266] DB05630|Sodium stibogluconate TOP1 DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0016310| phosphorylation HK1;TOP1 33991:[DB05630 DB00351] DB05630|Sodium stibogluconate TOP1 DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0007059| chromosome segregation NR3C1;TOP1 33992:[DB05630 DB04858] DB05630|Sodium stibogluconate TOP1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 33993:[DB05630 DB11672] DB05630|Sodium stibogluconate TOP1 DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0048511| rhythmic process PPARG;TOP1 GO:0042493| response to drug TOP1;CYP1A2;ABCB1;PPARG 33994:[DB05630 DB05457] DB05630|Sodium stibogluconate TOP1 DB05457|OSI-7904L TYMS common genes common pathways GO:0007623| circadian rhythm TYMS;TOP1 GO:0042493| response to drug TYMS;TOP1 33995:[DB05630 DB02032] DB05630|Sodium stibogluconate TOP1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 33996:[DB05630 DB00668] DB05630|Sodium stibogluconate TOP1 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0042493| response to drug ADRA1A;COMT;MAOB;TOP1 33997:[DB05630 DB09295] DB05630|Sodium stibogluconate TOP1 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 33998:[DB05630 DB00328] DB05630|Sodium stibogluconate TOP1 DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes common pathways GO:0016032| viral reproduction SLC10A1;TOP1 GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug ABCB1;ABCC2;UGT1A1;ABCC1;ABCC6;PPARG;ABCC4;PTGS2;TOP1 GO:0048511| rhythmic process PPARA;TOP1;PPARG 33999:[DB05630 DB00394] DB05630|Sodium stibogluconate TOP1 DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34000:[DB05630 DB00286] DB05630|Sodium stibogluconate TOP1 DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0042493| response to drug ABCC1;COMT;ABCB1;ABCC2;ABCG2;TOP1;CYP1A2;ABCC4 GO:0016032| viral reproduction TOP1;SLC10A1 34001:[DB05630 DB05395] DB05630|Sodium stibogluconate TOP1 DB05395|Amibegron ADRB3 common genes common pathways 34002:[DB05630 DB00577] DB05630|Sodium stibogluconate TOP1 DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways 34003:[DB05630 DB01397] DB05630|Sodium stibogluconate TOP1 DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34004:[DB05630 DB00532] DB05630|Sodium stibogluconate TOP1 DB00532|Mephenytoin SCN5A;NR1I2;CYP2C19;CYP2B6;CYP1A2;CYP2D6;CYP2C8;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34005:[DB05630 DB01017] DB05630|Sodium stibogluconate TOP1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0042493| response to drug CASP3;TOP1 34006:[DB05630 DB01149] DB05630|Sodium stibogluconate TOP1 DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0042493| response to drug SLC6A2;ADRA1A;ABCB1;SLC6A3;HTR2C;TOP1;HTR2A;SLC6A4 GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0016032| viral reproduction TOP1;HTR2A 34007:[DB05630 DB14498] DB05630|Sodium stibogluconate TOP1 DB14498|Potassium acetate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 34008:[DB05630 DB05478] DB05630|Sodium stibogluconate TOP1 DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways 34009:[DB05630 DB00456] DB05630|Sodium stibogluconate TOP1 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 34010:[DB05630 DB03214] DB05630|Sodium stibogluconate TOP1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways 34011:[DB05630 DB11582] DB05630|Sodium stibogluconate TOP1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 34012:[DB05630 DB06081] DB05630|Sodium stibogluconate TOP1 DB06081|Caplacizumab VWF common genes common pathways 34013:[DB05630 DB12637] DB05630|Sodium stibogluconate TOP1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 34014:[DB05630 DB01190] DB05630|Sodium stibogluconate TOP1 DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways 34015:[DB05630 DB00982] DB05630|Sodium stibogluconate TOP1 DB00982|Isotretinoin RARA common genes common pathways 34016:[DB05630 DB01328] DB05630|Sodium stibogluconate TOP1 DB01328|Cefonicid mrcA;ALB common genes common pathways 34017:[DB05630 DB04817] DB05630|Sodium stibogluconate TOP1 DB04817|Metamizole PTGS1;CYP2B6;CYP3A4 common genes common pathways 34018:[DB05630 DB00202] DB05630|Sodium stibogluconate TOP1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0042493| response to drug BCHE;TOP1 34019:[DB05630 DB13178] DB05630|Sodium stibogluconate TOP1 DB13178|Inositol SLC5A3 common genes common pathways 34020:[DB05630 DB11692] DB05630|Sodium stibogluconate TOP1 DB11692|Pavinetant TACR3 common genes common pathways 34021:[DB05630 DB06735] DB05630|Sodium stibogluconate TOP1 DB06735|Enclomiphene CYP2D6 common genes common pathways 34022:[DB05630 DB01364] DB05630|Sodium stibogluconate TOP1 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0006260| DNA replication ACHE;TOP1 GO:0042493| response to drug BCHE;SLC6A2;ADRA1A;TOP1 34023:[DB05630 DB06697] DB05630|Sodium stibogluconate TOP1 DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways 34024:[DB05630 DB04381] DB05630|Sodium stibogluconate TOP1 DB04381|Crotonaldehyde ALDH2 common genes common pathways 34025:[DB05630 DB01095] DB05630|Sodium stibogluconate TOP1 DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;ABCC2;CYP1A1;UGT1A1 34026:[DB05630 DB03991] DB05630|Sodium stibogluconate TOP1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways 34027:[DB05630 DB05200] DB05630|Sodium stibogluconate TOP1 DB05200|AT2220 GAA common genes common pathways 34028:[DB05630 DB14063] DB05630|Sodium stibogluconate TOP1 DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34029:[DB05630 DB04953] DB05630|Sodium stibogluconate TOP1 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1 34030:[DB05630 DB06707] DB05630|Sodium stibogluconate TOP1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways 34031:[DB05630 DB09143] DB05630|Sodium stibogluconate TOP1 DB09143|Sonidegib SMO;CYP3A4 common genes common pathways 34032:[DB05630 DB00293] DB05630|Sodium stibogluconate TOP1 DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0007623| circadian rhythm TOP1;TYMS GO:0042493| response to drug TOP1;TYMS 34033:[DB05630 DB00320] DB05630|Sodium stibogluconate TOP1 DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;HTR2B;ABCB1;HTR1B GO:0016310| phosphorylation HTR2B;TOP1 34034:[DB05630 DB00835] DB05630|Sodium stibogluconate TOP1 DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 34035:[DB05630 DB00576] DB05630|Sodium stibogluconate TOP1 DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways 34036:[DB05630 DB01213] DB05630|Sodium stibogluconate TOP1 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;CAT 34037:[DB05630 DB00718] DB05630|Sodium stibogluconate TOP1 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0042493| response to drug NME1;ABCC4;TOP1;AK4 GO:0016310| phosphorylation NME2;NME1;AK2;TOP1;AK4 34038:[DB05630 DB00368] DB05630|Sodium stibogluconate TOP1 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0042493| response to drug ADRA1A;SLC6A2;TOP1 34039:[DB05630 DB00151] DB05630|Sodium stibogluconate TOP1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0042493| response to drug TOP1;MGMT;GCLM 34040:[DB05630 DB02751] DB05630|Sodium stibogluconate TOP1 DB02751|Glycocyamine GAMT common genes common pathways 34041:[DB05630 DB03185] DB05630|Sodium stibogluconate TOP1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 34042:[DB05630 DB09038] DB05630|Sodium stibogluconate TOP1 DB09038|Empagliflozin SLC5A2 common genes common pathways 34043:[DB05630 DB00074] DB05630|Sodium stibogluconate TOP1 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0016032| viral reproduction FCGR2B;IL2RB;TOP1 34044:[DB05630 DB00755] DB05630|Sodium stibogluconate TOP1 DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes common pathways GO:0016032| viral reproduction TOP1;RXRA GO:0016310| phosphorylation TOP1;PDK4 GO:0042493| response to drug CYP1A1;TOP1 34045:[DB05630 DB00749] DB05630|Sodium stibogluconate TOP1 DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways GO:0016032| viral reproduction RXRA;TOP1 GO:0042493| response to drug TOP1;PTGS2 34046:[DB05630 DB03128] DB05630|Sodium stibogluconate TOP1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0006260| DNA replication ACHE;TOP1 34047:[DB05630 DB01306] DB05630|Sodium stibogluconate TOP1 DB01306|Insulin Aspart INSR common genes common pathways GO:0016310| phosphorylation TOP1;INSR 34048:[DB05630 DB14570] DB05630|Sodium stibogluconate TOP1 DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways 34049:[DB05630 DB05773] DB05630|Sodium stibogluconate TOP1 DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0016310| phosphorylation ERBB2;TOP1 34050:[DB05630 DB00148] DB05630|Sodium stibogluconate TOP1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0016310| phosphorylation CKMT1A;CKM;CKB;CKMT2;TOP1 34051:[DB05630 DB06090] DB05630|Sodium stibogluconate TOP1 DB06090|Bradanicline CHRNA7 common genes common pathways 34052:[DB05630 DB01614] DB05630|Sodium stibogluconate TOP1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0042493| response to drug HTR2A;TOP1;DRD1;ADRA1A;DRD2 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 34053:[DB05630 DB13151] DB05630|Sodium stibogluconate TOP1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0007623| circadian rhythm TOP1;F7 34054:[DB05630 DB00475] DB05630|Sodium stibogluconate TOP1 DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;TOP1 34055:[DB05630 DB01431] DB05630|Sodium stibogluconate TOP1 DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 34056:[DB05630 DB01610] DB05630|Sodium stibogluconate TOP1 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways 34057:[DB05630 DB01382] DB05630|Sodium stibogluconate TOP1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0042493| response to drug ABCC8;TOP1 34058:[DB05630 DB08836] DB05630|Sodium stibogluconate TOP1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways 34059:[DB05630 DB00165] DB05630|Sodium stibogluconate TOP1 DB00165|Pyridoxine PDXK;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1 GO:0016310| phosphorylation PDXK;TOP1 34060:[DB05630 DB00714] DB05630|Sodium stibogluconate TOP1 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0048511| rhythmic process TOP1;DRD4 GO:0042493| response to drug DRD1;TOP1;HTR2A;HTR1B;DRD2;HTR2B;HTR2C;DRD3 GO:0032922| circadian regulation of gene expression DRD2;DRD3;TOP1 GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 34061:[DB05630 DB01600] DB05630|Sodium stibogluconate TOP1 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34062:[DB05630 DB09099] DB05630|Sodium stibogluconate TOP1 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34063:[DB05630 DB06699] DB05630|Sodium stibogluconate TOP1 DB06699|Degarelix GNRHR common genes common pathways 34064:[DB05630 DB00176] DB05630|Sodium stibogluconate TOP1 DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A1;SLC6A4;CYP2E1;TOP1;CYP1A2 GO:0007623| circadian rhythm SLC6A4;TOP1 34065:[DB05630 DB05687] DB05630|Sodium stibogluconate TOP1 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug HTR2A;TOP1;DRD2 34066:[DB05630 DB06822] DB05630|Sodium stibogluconate TOP1 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways 34067:[DB05630 DB00200] DB05630|Sodium stibogluconate TOP1 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways 34068:[DB05630 DB09564] DB05630|Sodium stibogluconate TOP1 DB09564|Insulin Degludec INSR common genes common pathways GO:0016310| phosphorylation TOP1;INSR 34069:[DB05630 DB14517] DB05630|Sodium stibogluconate TOP1 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 34070:[DB05630 DB01212] DB05630|Sodium stibogluconate TOP1 DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 34071:[DB05630 DB11921] DB05630|Sodium stibogluconate TOP1 DB11921|Deflazacort CYP3A4 common genes common pathways 34072:[DB05630 DB01289] DB05630|Sodium stibogluconate TOP1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways 34073:[DB05630 DB00762] DB05630|Sodium stibogluconate TOP1 DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes TOP1 common pathways GO:0007623| circadian rhythm TOP1 GO:0007059| chromosome segregation TOP1;TOP1MT GO:0016925| protein sumoylation TOP1 GO:0042493| response to drug TOP1;UGT1A1;BCHE;ABCC1;ABCB1;ABCG2;ABCC2 GO:0032922| circadian regulation of gene expression TOP1 GO:0006338| chromatin remodeling TOP1MT;TOP1 GO:0048511| rhythmic process TOP1 GO:0012501| programmed cell death TOP1 GO:0018105| peptidyl-serine phosphorylation TOP1 GO:0006260| DNA replication TOP1MT;TOP1 GO:0040016| embryonic cleavage TOP1 GO:0016032| viral reproduction TOP1 GO:0016310| phosphorylation TOP1 GO:0006265| DNA topological change TOP1MT;TOP1 34074:[DB05630 DB00357] DB05630|Sodium stibogluconate TOP1 DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways 34075:[DB05630 DB00243] DB05630|Sodium stibogluconate TOP1 DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways 34076:[DB05630 DB06191] DB05630|Sodium stibogluconate TOP1 DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34077:[DB05630 DB00884] DB05630|Sodium stibogluconate TOP1 DB00884|Risedronate FDPS;PTGS2 common genes common pathways GO:0016032| viral reproduction TOP1;FDPS GO:0042493| response to drug PTGS2;TOP1 34078:[DB05630 DB01014] DB05630|Sodium stibogluconate TOP1 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0042493| response to drug PPARG;TOP1;PTGS2 GO:0048511| rhythmic process PPARG;TOP1 34079:[DB05630 DB04334] DB05630|Sodium stibogluconate TOP1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways 34080:[DB05630 DB09309] DB05630|Sodium stibogluconate TOP1 DB09309|Kitasamycin CYP3A4 common genes common pathways 34081:[DB05630 DB00993] DB05630|Sodium stibogluconate TOP1 DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34082:[DB05630 DB01056] DB05630|Sodium stibogluconate TOP1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34083:[DB05630 DB00555] DB05630|Sodium stibogluconate TOP1 DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug ADORA2A;UGT1A1;ABCB1;DRD2;ADRA1A;HTR2A;TOP1;GABRG3;DRD1 GO:0016032| viral reproduction TOP1;HTR2A 34084:[DB05630 DB11077] DB05630|Sodium stibogluconate TOP1 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways 34085:[DB05630 DB11487] DB05630|Sodium stibogluconate TOP1 DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways 34086:[DB05630 DB04896] DB05630|Sodium stibogluconate TOP1 DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug TOP1;GRIN2A;SLC6A4;SLC6A2 34087:[DB05630 DB01354] DB05630|Sodium stibogluconate TOP1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 34088:[DB05630 DB01255] DB05630|Sodium stibogluconate TOP1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways 34089:[DB05630 DB01253] DB05630|Sodium stibogluconate TOP1 DB01253|Ergometrine ADRA1A;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ADRA1A;TOP1 34090:[DB05630 DB01202] DB05630|Sodium stibogluconate TOP1 DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;ABCC2;ABCB1 34091:[DB05630 DB04263] DB05630|Sodium stibogluconate TOP1 DB04263|Geneticin ODC1 common genes common pathways 34092:[DB05630 DB00344] DB05630|Sodium stibogluconate TOP1 DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;SLC6A4;SLC6A2;ABCB1 GO:0007623| circadian rhythm SLC6A4;TOP1 34093:[DB05630 DB00007] DB05630|Sodium stibogluconate TOP1 DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways 34094:[DB05630 DB06420] DB05630|Sodium stibogluconate TOP1 DB06420|Annamycin TOP2A common genes common pathways GO:0016925| protein sumoylation TOP1;TOP2A GO:0007059| chromosome segregation TOP2A;TOP1 GO:0048511| rhythmic process TOP2A;TOP1 GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP1;TOP2A 34095:[DB05630 DB09238] DB05630|Sodium stibogluconate TOP1 DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1 34096:[DB05630 DB00301] DB05630|Sodium stibogluconate TOP1 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways 34097:[DB05630 DB00547] DB05630|Sodium stibogluconate TOP1 DB00547|Desoximetasone NR3C1 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 34098:[DB05630 DB00868] DB05630|Sodium stibogluconate TOP1 DB00868|Benzonatate SCN5A common genes common pathways 34099:[DB05630 DB00255] DB05630|Sodium stibogluconate TOP1 DB00255|Diethylstilbestrol ESR1;ESRRG;ESR2;ESRRA;ESRRB;NCOA2;NR1I2;AR;SHBG;COMT;CYP19A1;CYP3A4;CYP2C8;CYP2C9;CYP2E1;TTR;ABCG2;ABCB1;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0048511| rhythmic process TOP1;NCOA2 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0032922| circadian regulation of gene expression NCOA2;TOP1 GO:0042493| response to drug COMT;ABCG2;ABCB1;CYP2E1;TOP1 GO:0007623| circadian rhythm NCOA2;TOP1 34100:[DB05630 DB09103] DB05630|Sodium stibogluconate TOP1 DB09103|Ancestim KIT common genes common pathways GO:0016310| phosphorylation KIT;TOP1 34101:[DB05630 DB00455] DB05630|Sodium stibogluconate TOP1 DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34102:[DB05630 DB05077] DB05630|Sodium stibogluconate TOP1 DB05077|SLV319 CNR1 common genes common pathways 34103:[DB05630 DB04573] DB05630|Sodium stibogluconate TOP1 DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0006338| chromatin remodeling TOP1;ESR1 34104:[DB05630 DB06963] DB05630|Sodium stibogluconate TOP1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0016310| phosphorylation TOP1;PLK1 GO:0018105| peptidyl-serine phosphorylation TOP1;PLK1 34105:[DB05630 DB00893] DB05630|Sodium stibogluconate TOP1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways 34106:[DB05630 DB13874] DB05630|Sodium stibogluconate TOP1 DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;ABCB1;ABCG2;UGT1A1 34107:[DB05630 DB06802] DB05630|Sodium stibogluconate TOP1 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34108:[DB05630 DB01764] DB05630|Sodium stibogluconate TOP1 DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways 34109:[DB05630 DB06144] DB05630|Sodium stibogluconate TOP1 DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0042493| response to drug ADRA1A;DRD2;HTR2C;TOP1;HTR2A GO:0032922| circadian regulation of gene expression DRD2;TOP1 34110:[DB05630 DB00797] DB05630|Sodium stibogluconate TOP1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug ADRA1A;TOP1 34111:[DB05630 DB00345] DB05630|Sodium stibogluconate TOP1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways GO:0042493| response to drug TOP1;ABCC2;ABCC1 34112:[DB05630 DB02783] DB05630|Sodium stibogluconate TOP1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 34113:[DB05630 DB06444] DB05630|Sodium stibogluconate TOP1 DB06444|Dexanabinol TNF common genes common pathways 34114:[DB05630 DB14072] DB05630|Sodium stibogluconate TOP1 DB14072|Reversin 121 ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34115:[DB05630 DB05758] DB05630|Sodium stibogluconate TOP1 DB05758|CYT007-TNFQb TNF common genes common pathways 34116:[DB05630 DB01136] DB05630|Sodium stibogluconate TOP1 DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes common pathways GO:0016032| viral reproduction TOP1;VCAM1 GO:0042493| response to drug TOP1;CYP1A2;CYP2E1;UGT1A1;CYP1A1;ADRA1A;ABCB1 34117:[DB05630 DB00717] DB05630|Sodium stibogluconate TOP1 DB00717|Norethisterone PGR;CYP3A4;CYP3A5;CYP3A7;CYP2C19;ALB;SHBG;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34118:[DB05630 DB06495] DB05630|Sodium stibogluconate TOP1 DB06495|Onercept TNF common genes common pathways 34119:[DB05630 DB01621] DB05630|Sodium stibogluconate TOP1 DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug DRD2;TOP1;HTR2A;DRD1 GO:0016032| viral reproduction HTR2A;TOP1 34120:[DB05630 DB11471] DB05630|Sodium stibogluconate TOP1 DB11471|Tilmicosin CYP3A4 common genes common pathways 34121:[DB05630 DB04844] DB05630|Sodium stibogluconate TOP1 DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug TOP1;DRD2 34122:[DB05630 DB00425] DB05630|Sodium stibogluconate TOP1 DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34123:[DB05630 DB11278] DB05630|Sodium stibogluconate TOP1 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 34124:[DB05630 DB14502] DB05630|Sodium stibogluconate TOP1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction TOP1;SLC20A2 GO:0042493| response to drug SLC34A1;TOP1 34125:[DB05630 DB09036] DB05630|Sodium stibogluconate TOP1 DB09036|Siltuximab IL6;CYP3A4 common genes common pathways 34126:[DB05630 DB03542] DB05630|Sodium stibogluconate TOP1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 34127:[DB05630 DB11979] DB05630|Sodium stibogluconate TOP1 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34128:[DB05630 DB06510] DB05630|Sodium stibogluconate TOP1 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;PPARG;UGT1A1 GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0048511| rhythmic process TOP1;PPARA;PPARG 34129:[DB05630 DB07776] DB05630|Sodium stibogluconate TOP1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways 34130:[DB05630 DB00922] DB05630|Sodium stibogluconate TOP1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0042493| response to drug KCNJ11;TOP1;PDE3A 34131:[DB05630 DB01176] DB05630|Sodium stibogluconate TOP1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways 34132:[DB05630 DB00962] DB05630|Sodium stibogluconate TOP1 DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0042493| response to drug TSPO;TOP1 34133:[DB05630 DB09328] DB05630|Sodium stibogluconate TOP1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;CYP2E1 34134:[DB05630 DB01026] DB05630|Sodium stibogluconate TOP1 DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;ABCB1;CYP1A1;UGT1A1 34135:[DB05630 DB00784] DB05630|Sodium stibogluconate TOP1 DB00784|Mefenamic acid PTGS2;PTGS1;CYP2C9;CYP2C8;UGT1A9;ALB common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34136:[DB05630 DB11155] DB05630|Sodium stibogluconate TOP1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A1 34137:[DB05630 DB11751] DB05630|Sodium stibogluconate TOP1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways 34138:[DB05630 DB01203] DB05630|Sodium stibogluconate TOP1 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34139:[DB05630 DB04911] DB05630|Sodium stibogluconate TOP1 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways 34140:[DB05630 DB06228] DB05630|Sodium stibogluconate TOP1 DB06228|Rivaroxaban F10;CYP3A4;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;TOP1 34141:[DB05630 DB11090] DB05630|Sodium stibogluconate TOP1 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 34142:[DB05630 DB01097] DB05630|Sodium stibogluconate TOP1 DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0042493| response to drug DHODH;CYP1A2;TOP1;ABCG2;PTK2B GO:0032922| circadian regulation of gene expression TOP1;AHR GO:0048511| rhythmic process TOP1;AHR GO:0016310| phosphorylation TOP1;PTK2B 34143:[DB05630 DB00670] DB05630|Sodium stibogluconate TOP1 DB00670|Pirenzepine CHRM1 common genes common pathways 34144:[DB05630 DB01169] DB05630|Sodium stibogluconate TOP1 DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0007623| circadian rhythm TOP1;JUN GO:0042493| response to drug CCND1;CYP1A1;HDAC1;ABCB1;CDKN1A;ABCC2;JUN;TOP1 GO:0032922| circadian regulation of gene expression PML;TOP1;HDAC1 GO:0006338| chromatin remodeling TOP1;HDAC1 GO:0048511| rhythmic process PML;TOP1;HDAC1 GO:0018105| peptidyl-serine phosphorylation MAPK1;IKBKB;AKT1;TOP1;MAPK3 GO:0016032| viral reproduction PML;TOP1;MAPK3;HDAC1;MAPK1 GO:0016310| phosphorylation MAPK3;AKT1;TOP1;IKBKB;MAPK1 34145:[DB05630 DB04878] DB05630|Sodium stibogluconate TOP1 DB04878|Voglibose MGAM common genes common pathways 34146:[DB05630 DB00113] DB05630|Sodium stibogluconate TOP1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways 34147:[DB05630 DB00831] DB05630|Sodium stibogluconate TOP1 DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0042493| response to drug DRD2;ADRA1A;ABCB1;CYP1A2;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 34148:[DB05630 DB00311] DB05630|Sodium stibogluconate TOP1 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways 34149:[DB05630 DB00308] DB05630|Sodium stibogluconate TOP1 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0042493| response to drug TOP1;KCNJ11 34150:[DB05630 DB09225] DB05630|Sodium stibogluconate TOP1 DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug TOP1;CYP1A2;HTR2A;DRD1;SLC6A4;SLC6A2;DRD2 GO:0007623| circadian rhythm HTR7;SLC6A4;TOP1 34151:[DB05630 DB09237] DB05630|Sodium stibogluconate TOP1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0007623| circadian rhythm TOP1;NOS2 34152:[DB05630 DB06762] DB05630|Sodium stibogluconate TOP1 DB06762|Pinacidil CYP3A4 common genes common pathways 34153:[DB05630 DB00570] DB05630|Sodium stibogluconate TOP1 DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCC2;ABCB1;ABCC6;ABCC1;JUN;TOP1 GO:0007623| circadian rhythm TOP1;JUN 34154:[DB05630 DB04348] DB05630|Sodium stibogluconate TOP1 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0042493| response to drug ABCC4;TOP1;ABCC2;ABCG2;ABCB1;ABCC1 GO:0016032| viral reproduction TOP1;SLC10A1 34155:[DB05630 DB00463] DB05630|Sodium stibogluconate TOP1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;TOP1 34156:[DB05630 DB00680] DB05630|Sodium stibogluconate TOP1 DB00680|Moricizine SCN5A common genes common pathways 34157:[DB05630 DB00579] DB05630|Sodium stibogluconate TOP1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug SLC6A2;SLC6A3;TOP1;SLC6A4 34158:[DB05630 DB04895] DB05630|Sodium stibogluconate TOP1 DB04895|Pegaptanib NRP1 common genes common pathways 34159:[DB05630 DB14499] DB05630|Sodium stibogluconate TOP1 DB14499|Potassium sulfate ATP1A1 common genes common pathways GO:0042493| response to drug TOP1;ATP1A1 34160:[DB05630 DB00678] DB05630|Sodium stibogluconate TOP1 DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;SLC22A12;TOP1 34161:[DB05630 DB06695] DB05630|Sodium stibogluconate TOP1 DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34162:[DB05630 DB14538] DB05630|Sodium stibogluconate TOP1 DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 GO:0042493| response to drug TOP1;ANXA1;ABCG2;HSD11B2;ABCB1 34163:[DB05630 DB06283] DB05630|Sodium stibogluconate TOP1 DB06283|Ziconotide CYP3A4 common genes common pathways 34164:[DB05630 DB08819] DB05630|Sodium stibogluconate TOP1 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34165:[DB05630 DB01384] DB05630|Sodium stibogluconate TOP1 DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34166:[DB05630 DB06712] DB05630|Sodium stibogluconate TOP1 DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 34167:[DB05630 DB00627] DB05630|Sodium stibogluconate TOP1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0042493| response to drug TOP1;NNMT 34168:[DB05630 DB00050] DB05630|Sodium stibogluconate TOP1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways 34169:[DB05630 DB00401] DB05630|Sodium stibogluconate TOP1 DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34170:[DB05630 DB01054] DB05630|Sodium stibogluconate TOP1 DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34171:[DB05630 DB05983] DB05630|Sodium stibogluconate TOP1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0016032| viral reproduction NFKBIA;TOP1 34172:[DB05630 DB09336] DB05630|Sodium stibogluconate TOP1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways 34173:[DB05630 DB04100] DB05630|Sodium stibogluconate TOP1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0042493| response to drug TOP1;ABCC2 34174:[DB05630 DB00126] DB05630|Sodium stibogluconate TOP1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0042493| response to drug PAM;TOP1 34175:[DB05630 DB01274] DB05630|Sodium stibogluconate TOP1 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways 34176:[DB05630 DB09413] DB05630|Sodium stibogluconate TOP1 DB09413|Monopotassium phosphate ALPI common genes common pathways 34177:[DB05630 DB06360] DB05630|Sodium stibogluconate TOP1 DB06360|Lucatumumab CD40 common genes common pathways 34178:[DB05630 DB00035] DB05630|Sodium stibogluconate TOP1 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34179:[DB05630 DB02745] DB05630|Sodium stibogluconate TOP1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 34180:[DB05630 DB00669] DB05630|Sodium stibogluconate TOP1 DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;HTR1B;ABCG2 34181:[DB05630 DB09217] DB05630|Sodium stibogluconate TOP1 DB09217|Firocoxib PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34182:[DB05630 DB01151] DB05630|Sodium stibogluconate TOP1 DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug SLC6A4;CYP1A2;TOP1;CYP2E1;HTR2A;ABCB1;ADRA1A;DRD2;HTR2C;SMPD1;SLC6A2 GO:0007623| circadian rhythm SLC6A4;TOP1 34183:[DB05630 DB00430] DB05630|Sodium stibogluconate TOP1 DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways 34184:[DB05630 DB03506] DB05630|Sodium stibogluconate TOP1 DB03506|9-Deazaadenine APRT common genes common pathways 34185:[DB05630 DB12119] DB05630|Sodium stibogluconate TOP1 DB12119|Gevokizumab IL1B common genes common pathways 34186:[DB05630 DB06636] DB05630|Sodium stibogluconate TOP1 DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34187:[DB05630 DB00081] DB05630|Sodium stibogluconate TOP1 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FCGR2B;TOP1 34188:[DB05630 DB08049] DB05630|Sodium stibogluconate TOP1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0042493| response to drug TOP1;COMT 34189:[DB05630 DB11198] DB05630|Sodium stibogluconate TOP1 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34190:[DB05630 DB01330] DB05630|Sodium stibogluconate TOP1 DB01330|Cefotetan ALB common genes common pathways 34191:[DB05630 DB00490] DB05630|Sodium stibogluconate TOP1 DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug TOP1;ABCB1;DRD2 34192:[DB05630 DB12474] DB05630|Sodium stibogluconate TOP1 DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways 34193:[DB05630 DB01043] DB05630|Sodium stibogluconate TOP1 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0042493| response to drug DRD2;GRIN2A;TOP1 GO:0032922| circadian regulation of gene expression TOP1;DRD2 34194:[DB05630 DB09194] DB05630|Sodium stibogluconate TOP1 DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug TOP1;HTR2A;SLC6A4;SLC6A2;DRD2;ADRA1A;HTR2C;SLC6A3 GO:0007623| circadian rhythm TOP1;SLC6A4 34195:[DB05630 DB00968] DB05630|Sodium stibogluconate TOP1 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0042493| response to drug COMT;TOP1 GO:0007623| circadian rhythm TOP1;DDC 34196:[DB05630 DB00910] DB05630|Sodium stibogluconate TOP1 DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways 34197:[DB05630 DB08952] DB05630|Sodium stibogluconate TOP1 DB08952|Indenolol CYP2D6 common genes common pathways 34198:[DB05630 DB01107] DB05630|Sodium stibogluconate TOP1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;TOP1 34199:[DB05630 DB01076] DB05630|Sodium stibogluconate TOP1 DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0048511| rhythmic process AHR;TOP1 GO:0042493| response to drug ABCC4;TOP1;ABCC2;ABCB1;UGT1A1;ABCC1 GO:0032922| circadian regulation of gene expression TOP1;AHR 34200:[DB05630 DB09073] DB05630|Sodium stibogluconate TOP1 DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0016310| phosphorylation TOP1;CDK4;CDK6 GO:0042493| response to drug TOP1;CDK4 GO:0007623| circadian rhythm TOP1;CDK4 34201:[DB05630 DB08816] DB05630|Sodium stibogluconate TOP1 DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34202:[DB05630 DB00424] DB05630|Sodium stibogluconate TOP1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 34203:[DB05630 DB09045] DB05630|Sodium stibogluconate TOP1 DB09045|Dulaglutide GLP1R common genes common pathways 34204:[DB05630 DB00706] DB05630|Sodium stibogluconate TOP1 DB00706|Tamsulosin ADRA1A;ADRA1D;ADRA1B;CYP3A4;CYP2D6;ORM1 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 34205:[DB05630 DB06307] DB05630|Sodium stibogluconate TOP1 DB06307|Apoptone BCL2 common genes common pathways GO:0018105| peptidyl-serine phosphorylation BCL2;TOP1 GO:0042493| response to drug TOP1;BCL2 34206:[DB05630 DB01418] DB05630|Sodium stibogluconate TOP1 DB01418|Acenocoumarol VKORC1;CYP2C9;CYP1A2;CYP2C19;CYP3A4;ALB;ORM1 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34207:[DB05630 DB09105] DB05630|Sodium stibogluconate TOP1 DB09105|Asfotase Alfa S1PR1 common genes common pathways 34208:[DB05630 DB09299] DB05630|Sodium stibogluconate TOP1 DB09299|Tenofovir alafenamide pol;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34209:[DB05630 DB12130] DB05630|Sodium stibogluconate TOP1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0016310| phosphorylation TOP1;ALK 34210:[DB05630 DB00356] DB05630|Sodium stibogluconate TOP1 DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A2;TOP1;CYP1A1 34211:[DB05630 DB09039] DB05630|Sodium stibogluconate TOP1 DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways 34212:[DB05630 DB04620] DB05630|Sodium stibogluconate TOP1 DB04620|Cycloleucine GRIN1 common genes common pathways 34213:[DB05630 DB01332] DB05630|Sodium stibogluconate TOP1 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways 34214:[DB05630 DB06016] DB05630|Sodium stibogluconate TOP1 DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0042493| response to drug TOP1;HTR2A;DRD2;HTR2B;DRD3 GO:0016310| phosphorylation TOP1;HTR2B GO:0016032| viral reproduction HTR2A;TOP1 34215:[DB05630 DB09289] DB05630|Sodium stibogluconate TOP1 DB09289|Tianeptine GRIA1;OPRM1;HTR1A;DRD3;CYP3A4 common genes common pathways GO:0042493| response to drug DRD3;TOP1 GO:0032922| circadian regulation of gene expression TOP1;DRD3 34216:[DB05630 DB04519] DB05630|Sodium stibogluconate TOP1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0048511| rhythmic process PPARA;TOP1 GO:0032922| circadian regulation of gene expression PPARA;TOP1 34217:[DB05630 DB00322] DB05630|Sodium stibogluconate TOP1 DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0007623| circadian rhythm TYMS;TOP1 GO:0042493| response to drug TYMS;TOP1 34218:[DB05630 DB03664] DB05630|Sodium stibogluconate TOP1 DB03664|UP5 CMPK1 common genes common pathways GO:0016310| phosphorylation TOP1;CMPK1 34219:[DB05630 DB01216] DB05630|Sodium stibogluconate TOP1 DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0042493| response to drug SRD5A1;SRD5A2;TOP1 34220:[DB05630 DB06730] DB05630|Sodium stibogluconate TOP1 DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways 34221:[DB05630 DB00191] DB05630|Sodium stibogluconate TOP1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug CYP1A2;TOP1;SLC6A4;MAOB;SLC6A2;SLC6A3 34222:[DB05630 DB06650] DB05630|Sodium stibogluconate TOP1 DB06650|Ofatumumab MS4A1 common genes common pathways 34223:[DB05630 DB00371] DB05630|Sodium stibogluconate TOP1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1;TOP1 34224:[DB05630 DB06684] DB05630|Sodium stibogluconate TOP1 DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A4;TOP1 GO:0007623| circadian rhythm TOP1;SLC6A4 34225:[DB05630 DB00530] DB05630|Sodium stibogluconate TOP1 DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0016310| phosphorylation TOP1;EGFR GO:0007623| circadian rhythm TOP1;EGFR GO:0042493| response to drug CYP1A1;UGT1A1;ABCG2;ABCB1;TOP1;CYP1A2 34226:[DB05630 DB00931] DB05630|Sodium stibogluconate TOP1 DB00931|Metacycline ALB common genes common pathways 34227:[DB05630 DB00903] DB05630|Sodium stibogluconate TOP1 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 34228:[DB05630 DB07789] DB05630|Sodium stibogluconate TOP1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;PLK1 GO:0016310| phosphorylation PLK1;TOP1 34229:[DB05630 DB01089] DB05630|Sodium stibogluconate TOP1 DB01089|Deserpidine SLC18A2 common genes common pathways 34230:[DB05630 DB13166] DB05630|Sodium stibogluconate TOP1 DB13166|Zofenopril ACE common genes common pathways 34231:[DB05630 DB01223] DB05630|Sodium stibogluconate TOP1 DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;CYP2E1;HDAC2;PDE3A GO:0032922| circadian regulation of gene expression TOP1;HDAC2 GO:0048511| rhythmic process HDAC2;TOP1 GO:0006338| chromatin remodeling HDAC2;TOP1 34232:[DB05630 DB00995] DB05630|Sodium stibogluconate TOP1 DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways GO:0016310| phosphorylation TOP1;IKBKB GO:0018105| peptidyl-serine phosphorylation TOP1;IKBKB 34233:[DB05630 DB00108] DB05630|Sodium stibogluconate TOP1 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0042493| response to drug ICAM1;TOP1 GO:0016032| viral reproduction FCGR2B;ICAM1;TOP1 34234:[DB05630 DB09236] DB05630|Sodium stibogluconate TOP1 DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways 34235:[DB05630 DB11858] DB05630|Sodium stibogluconate TOP1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways 34236:[DB05630 DB14132] DB05630|Sodium stibogluconate TOP1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0042493| response to drug ADORA2A;TOP1;CYP1A2 34237:[DB05630 DB09070] DB05630|Sodium stibogluconate TOP1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 34238:[DB05630 DB04905] DB05630|Sodium stibogluconate TOP1 DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;CYP1A1 34239:[DB05630 DB00487] DB05630|Sodium stibogluconate TOP1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0048511| rhythmic process TOP1;TOP2A GO:0042493| response to drug CYP1A2;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0007059| chromosome segregation TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP1 GO:0040016| embryonic cleavage TOP1;TOP2A 34240:[DB05630 DB13881] DB05630|Sodium stibogluconate TOP1 DB13881|Tisagenlecleucel CD19 common genes common pathways 34241:[DB05630 DB00682] DB05630|Sodium stibogluconate TOP1 DB00682|Warfarin VKORC1;NR1I2;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2C8;CYP2C18;CYP1A1;ALB;ORM1 common genes common pathways GO:0042493| response to drug CYP1A1;CYP1A2;TOP1 34242:[DB05630 DB05920] DB05630|Sodium stibogluconate TOP1 DB05920|RTA 744 TOP2A common genes common pathways GO:0006265| DNA topological change TOP1;TOP2A GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0048511| rhythmic process TOP1;TOP2A GO:0007059| chromosome segregation TOP2A;TOP1 GO:0016925| protein sumoylation TOP2A;TOP1 34243:[DB05630 DB11397] DB05630|Sodium stibogluconate TOP1 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0042493| response to drug BCHE;TOP1 34244:[DB05630 DB01589] DB05630|Sodium stibogluconate TOP1 DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 34245:[DB05630 DB00104] DB05630|Sodium stibogluconate TOP1 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways 34246:[DB05630 DB01064] DB05630|Sodium stibogluconate TOP1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0042493| response to drug TOP1;SOD1;CYP1A1 GO:0018105| peptidyl-serine phosphorylation TOP1;MAPK1 GO:0016032| viral reproduction TOP1;MAPK1;PIK3R1 GO:0016310| phosphorylation TOP1;MAPK1 34247:[DB05630 DB06538] DB05630|Sodium stibogluconate TOP1 DB06538|Robalzotan HTR1A common genes common pathways 34248:[DB05630 DB08190] DB05630|Sodium stibogluconate TOP1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways 34249:[DB05630 DB09280] DB05630|Sodium stibogluconate TOP1 DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34250:[DB05630 DB00633] DB05630|Sodium stibogluconate TOP1 DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1;CYP1A2;CYP1A1 34251:[DB05630 DB01349] DB05630|Sodium stibogluconate TOP1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways 34252:[DB05630 DB11774] DB05630|Sodium stibogluconate TOP1 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34253:[DB05630 DB00471] DB05630|Sodium stibogluconate TOP1 DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways 34254:[DB05630 DB01587] DB05630|Sodium stibogluconate TOP1 DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1;TSPO 34255:[DB05630 DB13500] DB05630|Sodium stibogluconate TOP1 DB13500|Otilonium CYP3A4 common genes common pathways 34256:[DB05630 DB09154] DB05630|Sodium stibogluconate TOP1 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 34257:[DB05630 DB01231] DB05630|Sodium stibogluconate TOP1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways 34258:[DB05630 DB00710] DB05630|Sodium stibogluconate TOP1 DB00710|Ibandronate FDPS common genes common pathways GO:0016032| viral reproduction FDPS;TOP1 34259:[DB05630 DB00511] DB05630|Sodium stibogluconate TOP1 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 34260:[DB05630 DB00917] DB05630|Sodium stibogluconate TOP1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;ABCC4 34261:[DB05630 DB01583] DB05630|Sodium stibogluconate TOP1 DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0016032| viral reproduction SLC10A1;TOP1 34262:[DB05630 DB00331] DB05630|Sodium stibogluconate TOP1 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways 34263:[DB05630 DB07700] DB05630|Sodium stibogluconate TOP1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways 34264:[DB05630 DB04951] DB05630|Sodium stibogluconate TOP1 DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34265:[DB05630 DB09230] DB05630|Sodium stibogluconate TOP1 DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways 34266:[DB05630 DB00850] DB05630|Sodium stibogluconate TOP1 DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;DRD1;DRD2 GO:0032922| circadian regulation of gene expression TOP1;DRD2 34267:[DB05630 DB04957] DB05630|Sodium stibogluconate TOP1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1 34268:[DB05630 DB05679] DB05630|Sodium stibogluconate TOP1 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways 34269:[DB05630 DB13203] DB05630|Sodium stibogluconate TOP1 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34270:[DB05630 DB06479] DB05630|Sodium stibogluconate TOP1 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34271:[DB05630 DB11760] DB05630|Sodium stibogluconate TOP1 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;TOP1 34272:[DB05630 DB01456] DB05630|Sodium stibogluconate TOP1 DB01456|5-androstenedione CYP3A4 common genes common pathways 34273:[DB05630 DB02691] DB05630|Sodium stibogluconate TOP1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways 34274:[DB05630 DB01399] DB05630|Sodium stibogluconate TOP1 DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34275:[DB05630 DB05514] DB05630|Sodium stibogluconate TOP1 DB05514|Cobiprostone CLCN2 common genes common pathways 34276:[DB05630 DB01559] DB05630|Sodium stibogluconate TOP1 DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 34277:[DB05630 DB09091] DB05630|Sodium stibogluconate TOP1 DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0006338| chromatin remodeling HDAC2;TOP1 GO:0048511| rhythmic process HDAC2;TOP1 GO:0007059| chromosome segregation TOP1;NR3C1 GO:0042493| response to drug TOP1;HDAC2 GO:0032922| circadian regulation of gene expression HDAC2;TOP1 34278:[DB05630 DB04794] DB05630|Sodium stibogluconate TOP1 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 34279:[DB05630 DB12141] DB05630|Sodium stibogluconate TOP1 DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1;AXL GO:0016310| phosphorylation FLT3;ALK;AXL;TOP1;HTR2B GO:0007623| circadian rhythm TOP1;HTR7 GO:0042493| response to drug TOP1;HTR2A;ABCB1;HTR1B;HTR2B;HTR2C;ABCG2 34280:[DB05630 DB00769] DB05630|Sodium stibogluconate TOP1 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 34281:[DB05630 DB00252] DB05630|Sodium stibogluconate TOP1 DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1;ABCC2;ABCB1 34282:[DB05630 DB00078] DB05630|Sodium stibogluconate TOP1 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction TOP1;FCGR2B 34283:[DB05630 DB09140] DB05630|Sodium stibogluconate TOP1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways 34284:[DB05630 DB04946] DB05630|Sodium stibogluconate TOP1 DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0032922| circadian regulation of gene expression TOP1;DRD3;DRD2 GO:0042493| response to drug DRD1;CYP2E1;HTR2A;TOP1;ADRA1A;DRD2;DRD3 GO:0007623| circadian rhythm TOP1;HTR7 GO:0048511| rhythmic process DRD4;TOP1 34285:[DB05630 DB11614] DB05630|Sodium stibogluconate TOP1 DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways 34286:[DB05630 DB14064] DB05630|Sodium stibogluconate TOP1 DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34287:[DB05630 DB06814] DB05630|Sodium stibogluconate TOP1 DB06814|Protokylol ADRB2 common genes common pathways 34288:[DB05630 DB07919] DB05630|Sodium stibogluconate TOP1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways 34289:[DB05630 DB09064] DB05630|Sodium stibogluconate TOP1 DB09064|Ciprofibrate PPARA common genes common pathways GO:0048511| rhythmic process PPARA;TOP1 GO:0032922| circadian regulation of gene expression PPARA;TOP1 34290:[DB05630 DB06145] DB05630|Sodium stibogluconate TOP1 DB06145|Spiramycin rplC;CYP3A4 common genes common pathways 34291:[DB05630 DB12118] DB05630|Sodium stibogluconate TOP1 DB12118|Sotatercept ACVR2A common genes common pathways GO:0016310| phosphorylation ACVR2A;TOP1 34292:[DB05630 DB00773] DB05630|Sodium stibogluconate TOP1 DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes common pathways GO:0006265| DNA topological change TOP2A;TOP1;TOP2B GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0048511| rhythmic process TOP1;TOP2A GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP2B;TOP1;TOP2A GO:0042493| response to drug ABCG2;ABCC2;ABCB1;UGT1A1;ABCC1;ABCC6;CYP2E1;PTGS2;CYP1A2;TOP1 34293:[DB05630 DB00580] DB05630|Sodium stibogluconate TOP1 DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34294:[DB05630 DB00515] DB05630|Sodium stibogluconate TOP1 DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes common pathways GO:0042493| response to drug ABCC6;BCHE;ABCB1;ABCC2;ABCG2;TOP1;PTGS2;SOD1 34295:[DB05630 DB00794] DB05630|Sodium stibogluconate TOP1 DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;GABRG3;UGT1A1 34296:[DB05630 DB00178] DB05630|Sodium stibogluconate TOP1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug BCHE;TOP1 34297:[DB05630 DB00592] DB05630|Sodium stibogluconate TOP1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways 34298:[DB05630 DB13996] DB05630|Sodium stibogluconate TOP1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0042493| response to drug TOP1;ATP1A1 34299:[DB05630 DB09227] DB05630|Sodium stibogluconate TOP1 DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways 34300:[DB05630 DB00815] DB05630|Sodium stibogluconate TOP1 DB00815|Sodium lauryl sulfate ALB common genes common pathways 34301:[DB05630 DB00839] DB05630|Sodium stibogluconate TOP1 DB00839|Tolazamide ABCC8;KCNJ11;CYP2C9 common genes common pathways GO:0042493| response to drug KCNJ11;ABCC8;TOP1 34302:[DB05630 DB00925] DB05630|Sodium stibogluconate TOP1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0042493| response to drug ADRA1A;TOP1 34303:[DB05630 DB12418] DB05630|Sodium stibogluconate TOP1 DB12418|Saccharin CA3 common genes common pathways 34304:[DB05630 DB00449] DB05630|Sodium stibogluconate TOP1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0006260| DNA replication TOP1;ACHE GO:0042493| response to drug TOP1;ADRA1A;BCHE 34305:[DB05630 DB12061] DB05630|Sodium stibogluconate TOP1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;DRD3;TOP1 GO:0042493| response to drug TOP1;DRD2;DRD3 GO:0048511| rhythmic process DRD4;TOP1 34306:[DB05630 DB06215] DB05630|Sodium stibogluconate TOP1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways 34307:[DB05630 DB09167] DB05630|Sodium stibogluconate TOP1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;HTR2A;SLC6A4;SLC6A2;ADRA1A GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 34308:[DB05630 DB00446] DB05630|Sodium stibogluconate TOP1 DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways GO:0016032| viral reproduction TOP1;CD55 34309:[DB05630 DB01973] DB05630|Sodium stibogluconate TOP1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 34310:[DB05630 DB00373] DB05630|Sodium stibogluconate TOP1 DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34311:[DB05630 DB09462] DB05630|Sodium stibogluconate TOP1 DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;TGFBR2;TOP1 GO:0016310| phosphorylation PAPSS1;TOP1;TGFBR2 GO:0018105| peptidyl-serine phosphorylation TGFBR2;TOP1 34312:[DB05630 DB02508] DB05630|Sodium stibogluconate TOP1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0016032| viral reproduction FDPS;TOP1 34313:[DB05630 DB00319] DB05630|Sodium stibogluconate TOP1 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways 34314:[DB05630 DB00393] DB05630|Sodium stibogluconate TOP1 DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0048511| rhythmic process AHR;TOP1 GO:0032922| circadian regulation of gene expression AHR;TOP1 34315:[DB05630 DB00716] DB05630|Sodium stibogluconate TOP1 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways 34316:[DB05630 DB00825] DB05630|Sodium stibogluconate TOP1 DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0042493| response to drug TRPA1;TOP1 34317:[DB05630 DB01105] DB05630|Sodium stibogluconate TOP1 DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug TOP1;SLC6A4;SLC6A2;SLC6A3 34318:[DB05630 DB00030] DB05630|Sodium stibogluconate TOP1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0006338| chromatin remodeling TOP1;RB1 GO:0016032| viral reproduction RB1;TOP1;IDE GO:0016310| phosphorylation TOP1;IGF1R;INSR 34319:[DB05630 DB00207] DB05630|Sodium stibogluconate TOP1 DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0006338| chromatin remodeling TOP1;PADI4 34320:[DB05630 DB01128] DB05630|Sodium stibogluconate TOP1 DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways 34321:[DB05630 DB13967] DB05630|Sodium stibogluconate TOP1 DB13967|Patent Blue ALB common genes common pathways 34322:[DB05630 DB06287] DB05630|Sodium stibogluconate TOP1 DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;MTOR GO:0016310| phosphorylation TOP1;MTOR GO:0042493| response to drug ABCB1;TOP1 34323:[DB05630 DB13884] DB05630|Sodium stibogluconate TOP1 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways 34324:[DB05630 DB11995] DB05630|Sodium stibogluconate TOP1 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug ABCG2;ABCB1;TOP1 34325:[DB05630 DB06457] DB05630|Sodium stibogluconate TOP1 DB06457|Tecastemizole KCNH2 common genes common pathways 34326:[DB05630 DB07117] DB05630|Sodium stibogluconate TOP1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 34327:[DB05630 DB00829] DB05630|Sodium stibogluconate TOP1 DB00829|Diazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9;CYP2B6;CYP2C18;CYP2C8;PTGS1;CYP2E1;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;GABRG3;TOP1;TSPO;CYP2E1 34328:[DB05630 DB06602] DB05630|Sodium stibogluconate TOP1 DB06602|Reslizumab IL5 common genes common pathways 34329:[DB05630 DB00864] DB05630|Sodium stibogluconate TOP1 DB00864|Tacrolimus FKBP1A;CYP3A7;CYP3A5;CYP3A4;ALB;ORM1;ABCB1;ABCA5;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34330:[DB05630 DB08059] DB05630|Sodium stibogluconate TOP1 DB08059|Wortmannin PIK3CG;PLK1;PIK3R1;PIK3CA common genes common pathways GO:0016310| phosphorylation TOP1;PIK3CA;PLK1;PIK3CG GO:0016032| viral reproduction TOP1;PIK3R1 GO:0018105| peptidyl-serine phosphorylation TOP1;PLK1 34331:[DB05630 DB00734] DB05630|Sodium stibogluconate TOP1 DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0048511| rhythmic process DRD4;TOP1 GO:0042493| response to drug DRD1;HTR2A;TOP1;HTR2C;DRD2;ADRA1A;DRD3 GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0007623| circadian rhythm HTR7;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 34332:[DB05630 DB12874] DB05630|Sodium stibogluconate TOP1 DB12874|Quizartinib FLT3 common genes common pathways GO:0016310| phosphorylation TOP1;FLT3 34333:[DB05630 DB08794] DB05630|Sodium stibogluconate TOP1 DB08794|Ethyl biscoumacetate GLUL;CYP3A4 common genes common pathways 34334:[DB05630 DB05750] DB05630|Sodium stibogluconate TOP1 DB05750|AVE-1625 CNR1 common genes common pathways 34335:[DB05630 DB00465] DB05630|Sodium stibogluconate TOP1 DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34336:[DB05630 DB00720] DB05630|Sodium stibogluconate TOP1 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0016032| viral reproduction SLC25A5;SLC25A4;TOP1;SLC25A6 GO:0007059| chromosome segregation SLC25A5;TOP1 GO:0042493| response to drug PTGS2;TOP1 34337:[DB05630 DB00653] DB05630|Sodium stibogluconate TOP1 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways 34338:[DB05630 DB01147] DB05630|Sodium stibogluconate TOP1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 34339:[DB05630 DB00573] DB05630|Sodium stibogluconate TOP1 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug TOP1;PTGS2;PPARG GO:0048511| rhythmic process PPARG;TOP1;PPARA 34340:[DB05630 DB00120] DB05630|Sodium stibogluconate TOP1 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0042493| response to drug TOP1;TH 34341:[DB05630 DB09329] DB05630|Sodium stibogluconate TOP1 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways 34342:[DB05630 DB00788] DB05630|Sodium stibogluconate TOP1 DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways GO:0042493| response to drug CYP1A2;PTGS2;TOP1;UGT1A1 34343:[DB05630 DB01267] DB05630|Sodium stibogluconate TOP1 DB01267|Paliperidone HTR2A;DRD2;HRH1;ADRA1A;ADRA1B;DRD4;HTR1D;DRD3;HTR2C;ADRA2A;ADRA2B;ADRA2C;HTR1A;DRD1;HTR7;CYP3A4;CYP2D6;CYP3A5;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0048511| rhythmic process TOP1;DRD4 GO:0042493| response to drug DRD1;HTR2A;TOP1;HTR2C;ABCB1;ADRA1A;DRD2;DRD3 GO:0032922| circadian regulation of gene expression DRD2;DRD3;TOP1 GO:0007623| circadian rhythm HTR7;TOP1 34344:[DB05630 DB00869] DB05630|Sodium stibogluconate TOP1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways 34345:[DB05630 DB06674] DB05630|Sodium stibogluconate TOP1 DB06674|Golimumab TNF common genes common pathways 34346:[DB05630 DB11636] DB05630|Sodium stibogluconate TOP1 DB11636|Nomegestrol CYP3A4 common genes common pathways 34347:[DB05630 DB00998] DB05630|Sodium stibogluconate TOP1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;HTR1B 34348:[DB05630 DB00133] DB05630|Sodium stibogluconate TOP1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0042493| response to drug SRR;TOP1 34349:[DB05630 DB13749] DB05630|Sodium stibogluconate TOP1 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0048511| rhythmic process ADCY1;TOP1 GO:0007623| circadian rhythm TOP1;ADCY1 GO:0042493| response to drug ATP1A1;TOP1;ADCY1 GO:0016310| phosphorylation PFKFB1;TOP1;CKB;ABL1 34350:[DB05630 DB12089] DB05630|Sodium stibogluconate TOP1 DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways 34351:[DB05630 DB07173] DB05630|Sodium stibogluconate TOP1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways GO:0016310| phosphorylation TOP1;ADK 34352:[DB05630 DB00539] DB05630|Sodium stibogluconate TOP1 DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A1;ABCB1 GO:0006338| chromatin remodeling ESR1;TOP1 34353:[DB05630 DB09061] DB05630|Sodium stibogluconate TOP1 DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0016032| viral reproduction VDAC1;HTR2A;TOP1 GO:0007623| circadian rhythm AANAT;TOP1 GO:0042493| response to drug SMPD1;ABCC1;TRPA1;CYP1A1;PPARG;ABCG2;TOP1;CYP1A2;PTGS2;HTR2A;SOD1;CAT GO:0048511| rhythmic process PPARG;AANAT;TOP1 34354:[DB05630 DB00066] DB05630|Sodium stibogluconate TOP1 DB00066|Follitropin FSHR common genes common pathways 34355:[DB05630 DB01873] DB05630|Sodium stibogluconate TOP1 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 34356:[DB05630 DB11595] DB05630|Sodium stibogluconate TOP1 DB11595|Atezolizumab CD274 common genes common pathways 34357:[DB05630 DB11135] DB05630|Sodium stibogluconate TOP1 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways 34358:[DB05630 DB00950] DB05630|Sodium stibogluconate TOP1 DB00950|Fexofenadine HRH1;ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34359:[DB05630 DB01582] DB05630|Sodium stibogluconate TOP1 DB01582|Sulfamethazine ALB common genes common pathways 34360:[DB05630 DB00397] DB05630|Sodium stibogluconate TOP1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0042493| response to drug TOP1;DRD1 34361:[DB05630 DB00908] DB05630|Sodium stibogluconate TOP1 DB00908|Quinidine SCN5A;KCNK1;KCNK6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A7;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP2B6;CYP2C9;CYP2C8;ORM1;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A8;ABCC2;SLC22A4;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2;CYP2E1;ADRA1A;ABCB1;ABCC2;CYP1A1 34362:[DB05630 DB05012] DB05630|Sodium stibogluconate TOP1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0042493| response to drug TOP1;SLC6A2 34363:[DB05630 DB00728] DB05630|Sodium stibogluconate TOP1 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways 34364:[DB05630 DB13876] DB05630|Sodium stibogluconate TOP1 DB13876|Brofaromine MAOA common genes common pathways 34365:[DB05630 DB09047] DB05630|Sodium stibogluconate TOP1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP1 GO:0007059| chromosome segregation TOP2A;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0048511| rhythmic process TOP1;TOP2A 34366:[DB05630 DB00643] DB05630|Sodium stibogluconate TOP1 DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1 34367:[DB05630 DB00612] DB05630|Sodium stibogluconate TOP1 DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways 34368:[DB05630 DB00213] DB05630|Sodium stibogluconate TOP1 DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;ABCG2 34369:[DB05630 DB08922] DB05630|Sodium stibogluconate TOP1 DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;DRD2;ADRA1A;TOP1;HTR2A GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0048511| rhythmic process TOP1;DRD4 GO:0016032| viral reproduction HTR2A;TOP1 34370:[DB05630 DB01576] DB05630|Sodium stibogluconate TOP1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0042493| response to drug SLC6A3;ADRA1A;SLC6A2;TOP1 34371:[DB05630 DB01068] DB05630|Sodium stibogluconate TOP1 DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1;TSPO;TOP1 34372:[DB05630 DB03615] DB05630|Sodium stibogluconate TOP1 DB03615|Ribostamycin P4HB;rpsL common genes common pathways 34373:[DB05630 DB00647] DB05630|Sodium stibogluconate TOP1 DB00647|Dextropropoxyphene OPRM1;OPRD1;OPRK1;CES1;CYP3A4;CYP2D6;CYP2C8 common genes common pathways 34374:[DB05630 DB11560] DB05630|Sodium stibogluconate TOP1 DB11560|Lesinurad SLC22A12;SLC22A11;CYP2C9 common genes common pathways GO:0042493| response to drug SLC22A12;TOP1 34375:[DB05630 DB13999] DB05630|Sodium stibogluconate TOP1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0042493| response to drug CALR;TOP1 34376:[DB05630 DB11598] DB05630|Sodium stibogluconate TOP1 DB11598|Antithrombin III human SERPINC1 common genes common pathways 34377:[DB05630 DB11450] DB05630|Sodium stibogluconate TOP1 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34378:[DB05630 DB02236] DB05630|Sodium stibogluconate TOP1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways 34379:[DB05630 DB00270] DB05630|Sodium stibogluconate TOP1 DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways 34380:[DB05630 DB00606] DB05630|Sodium stibogluconate TOP1 DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways 34381:[DB05630 DB08971] DB05630|Sodium stibogluconate TOP1 DB08971|Fluocortolone CYP3A4 common genes common pathways 34382:[DB05630 DB00999] DB05630|Sodium stibogluconate TOP1 DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways 34383:[DB05630 DB06691] DB05630|Sodium stibogluconate TOP1 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways 34384:[DB05630 DB13488] DB05630|Sodium stibogluconate TOP1 DB13488|Bencyclane CYP3A4 common genes common pathways 34385:[DB05630 DB00741] DB05630|Sodium stibogluconate TOP1 DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug ABCB1;ABCG2;ANXA1;HSD11B2;TOP1 34386:[DB05630 DB06210] DB05630|Sodium stibogluconate TOP1 DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;UGT1A1;ABCG2 34387:[DB05630 DB08872] DB05630|Sodium stibogluconate TOP1 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways 34388:[DB05630 DB06421] DB05630|Sodium stibogluconate TOP1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways GO:0006265| DNA topological change TOP2A;TOP2B;TOP1 GO:0040016| embryonic cleavage TOP1;TOP2A GO:0048511| rhythmic process TOP1;TOP2A GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP2B;TOP1;TOP2A 34389:[DB05630 DB13133] DB05630|Sodium stibogluconate TOP1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0042493| response to drug COL1A1;TOP1 34390:[DB05630 DB00233] DB05630|Sodium stibogluconate TOP1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0016310| phosphorylation CHUK;TOP1 GO:0018105| peptidyl-serine phosphorylation TOP1;CHUK GO:0042493| response to drug CHUK;TOP1;PTGS2 34391:[DB05630 DB11606] DB05630|Sodium stibogluconate TOP1 DB11606|Susoctocog alfa VWF common genes common pathways 34392:[DB05630 DB05155] DB05630|Sodium stibogluconate TOP1 DB05155|CR665 OPRK1 common genes common pathways 34393:[DB05630 DB09080] DB05630|Sodium stibogluconate TOP1 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways 34394:[DB05630 DB00561] DB05630|Sodium stibogluconate TOP1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0042493| response to drug TOP1;KCNK3 34395:[DB05630 DB11455] DB05630|Sodium stibogluconate TOP1 DB11455|Robenacoxib PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34396:[DB05630 DB01357] DB05630|Sodium stibogluconate TOP1 DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 34397:[DB05630 DB06654] DB05630|Sodium stibogluconate TOP1 DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0042493| response to drug CYP1A1;MAOB;ABCG2;CYP2E1;TOP1;CYP1A2 34398:[DB05630 DB00613] DB05630|Sodium stibogluconate TOP1 DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;CYP1A1 34399:[DB05630 DB01612] DB05630|Sodium stibogluconate TOP1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways 34400:[DB05630 DB09220] DB05630|Sodium stibogluconate TOP1 DB09220|Nicorandil ABCC9 common genes common pathways GO:0042493| response to drug ABCC9;TOP1 34401:[DB05630 DB14518] DB05630|Sodium stibogluconate TOP1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 34402:[DB05630 DB00867] DB05630|Sodium stibogluconate TOP1 DB00867|Ritodrine ADRB2;PGD common genes common pathways 34403:[DB05630 DB00169] DB05630|Sodium stibogluconate TOP1 DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0042493| response to drug TOP1;CYP1A1 34404:[DB05630 DB11901] DB05630|Sodium stibogluconate TOP1 DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0042493| response to drug GABRG3;TOP1;ABCG2;ABCB1 34405:[DB05630 DB01586] DB05630|Sodium stibogluconate TOP1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0042493| response to drug ABCC2;ABCC4;TOP1;CYP2E1 GO:0016032| viral reproduction TOP1;SLC10A1 34406:[DB05630 DB00880] DB05630|Sodium stibogluconate TOP1 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways 34407:[DB05630 DB05495] DB05630|Sodium stibogluconate TOP1 DB05495|PG-530742 MMP9 common genes common pathways 34408:[DB05630 DB11113] DB05630|Sodium stibogluconate TOP1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways 34409:[DB05630 DB11633] DB05630|Sodium stibogluconate TOP1 DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0042493| response to drug TOP1;KCNJ11;ABCB1;ABCG2 34410:[DB05630 DB01229] DB05630|Sodium stibogluconate TOP1 DB01229|Paclitaxel TUBB1;BCL2;NR1I2;MAP4;MAP2;MAPT;CYP3A5;CYP3A7;CYP2C8;CYP3A4;CYP19A1;CYP1B1;ABCB11;ABCB1;ABCC1;ABCC10;SLCO1B3;ABCG2;ABCC2 common genes common pathways GO:0018105| peptidyl-serine phosphorylation BCL2;TOP1 GO:0042493| response to drug TOP1;BCL2;ABCB1;ABCC2;ABCG2;ABCC1 34411:[DB05630 DB13772] DB05630|Sodium stibogluconate TOP1 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34412:[DB05630 DB12267] DB05630|Sodium stibogluconate TOP1 DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0042493| response to drug TOP1;ABCG2 GO:0007623| circadian rhythm TOP1;EGFR GO:0016310| phosphorylation ERBB2;IGF1R;MET;ALK;TOP1;FLT3;ERBB4;EGFR;ABL1;INSR 34413:[DB05630 DB03866] DB05630|Sodium stibogluconate TOP1 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34414:[DB05630 DB04828] DB05630|Sodium stibogluconate TOP1 DB04828|Zomepirac PTGDR2;CYP3A4;ALB common genes common pathways 34415:[DB05630 DB06077] DB05630|Sodium stibogluconate TOP1 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0042493| response to drug HTR2A;TOP1;DRD2 GO:0032922| circadian regulation of gene expression DRD2;TOP1 34416:[DB05630 DB09074] DB05630|Sodium stibogluconate TOP1 DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways 34417:[DB05630 DB05116] DB05630|Sodium stibogluconate TOP1 DB05116|Thymectacin TYMS common genes common pathways GO:0042493| response to drug TOP1;TYMS GO:0007623| circadian rhythm TYMS;TOP1 34418:[DB05630 DB00411] DB05630|Sodium stibogluconate TOP1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0006260| DNA replication TOP1;ACHE 34419:[DB05630 DB00918] DB05630|Sodium stibogluconate TOP1 DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes common pathways GO:0042493| response to drug HTR1B;CYP2E1;TOP1 34420:[DB05630 DB00957] DB05630|Sodium stibogluconate TOP1 DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0042493| response to drug ABCC2;TOP1 GO:0006338| chromatin remodeling TOP1;ESR1 34421:[DB05630 DB04860] DB05630|Sodium stibogluconate TOP1 DB04860|Isatoribine TLR7 common genes common pathways 34422:[DB05630 DB00291] DB05630|Sodium stibogluconate TOP1 DB00291|Chlorambucil GSTP1;SLCO1A2 common genes common pathways 34423:[DB05630 DB00841] DB05630|Sodium stibogluconate TOP1 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0042493| response to drug ADRA1A;COMT;TOP1 34424:[DB05630 DB08228] DB05630|Sodium stibogluconate TOP1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways 34425:[DB05630 DB05046] DB05630|Sodium stibogluconate TOP1 DB05046|V1003 OPRK1;OPRM1 common genes common pathways 34426:[DB05630 DB11817] DB05630|Sodium stibogluconate TOP1 DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0016310| phosphorylation PTK2B;JAK1;JAK2;JAK3;TOP1 GO:0042493| response to drug PTK2B;ABCG2;TOP1 34427:[DB05630 DB01214] DB05630|Sodium stibogluconate TOP1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways 34428:[DB05630 DB08808] DB05630|Sodium stibogluconate TOP1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways 34429:[DB05630 DB14059] DB05630|Sodium stibogluconate TOP1 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0042493| response to drug TOP1;PTGS2;RELA GO:0048511| rhythmic process NFKB2;TOP1 GO:0016032| viral reproduction TOP1;RELA 34430:[DB05630 DB07517] DB05630|Sodium stibogluconate TOP1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways 34431:[DB05630 DB01309] DB05630|Sodium stibogluconate TOP1 DB01309|Insulin Glulisine INSR common genes common pathways GO:0016310| phosphorylation TOP1;INSR 34432:[DB05630 DB00040] DB05630|Sodium stibogluconate TOP1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 34433:[DB05630 DB00309] DB05630|Sodium stibogluconate TOP1 DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways 34434:[DB05630 DB06736] DB05630|Sodium stibogluconate TOP1 DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34435:[DB05630 DB11988] DB05630|Sodium stibogluconate TOP1 DB11988|Ocrelizumab MS4A1 common genes common pathways 34436:[DB05630 DB05018] DB05630|Sodium stibogluconate TOP1 DB05018|Migalastat GLA;UGT1A1 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1 34437:[DB05630 DB00674] DB05630|Sodium stibogluconate TOP1 DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0006260| DNA replication TOP1;ACHE GO:0042493| response to drug BCHE;TOP1 34438:[DB05630 DB04881] DB05630|Sodium stibogluconate TOP1 DB04881|Elacridar ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;ABCG2 34439:[DB05630 DB03962] DB05630|Sodium stibogluconate TOP1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways 34440:[DB05630 DB06153] DB05630|Sodium stibogluconate TOP1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0042493| response to drug HTR2A;TOP1;HTR2C;HTR2B;ADRA1A;HTR1B GO:0016310| phosphorylation TOP1;HTR2B GO:0016032| viral reproduction TOP1;HTR2A 34441:[DB05630 DB08736] DB05630|Sodium stibogluconate TOP1 DB08736|S,R-Warfarin alcohol ALB common genes common pathways 34442:[DB05630 DB00695] DB05630|Sodium stibogluconate TOP1 DB00695|Furosemide SLC12A1;CA2;PGD;UGT1A1;ALB;SLC22A6;SLC22A5;SLC22A8;ABCC2;SLCO2A1;SLC22A11 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1;ABCC2 34443:[DB05630 DB00911] DB05630|Sodium stibogluconate TOP1 DB00911|Tinidazole CYP3A4;ABCB11 common genes common pathways 34444:[DB05630 DB09129] DB05630|Sodium stibogluconate TOP1 DB09129|Chromic chloride INSR common genes common pathways GO:0016310| phosphorylation TOP1;INSR 34445:[DB05630 DB06796] DB05630|Sodium stibogluconate TOP1 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways 34446:[DB05630 DB06533] DB05630|Sodium stibogluconate TOP1 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0048511| rhythmic process PPARG;TOP1;PPARA GO:0042493| response to drug PPARG;TOP1 GO:0032922| circadian regulation of gene expression TOP1;PPARA 34447:[DB05630 DB06472] DB05630|Sodium stibogluconate TOP1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction TOP1;ITGB3 34448:[DB05630 DB00384] DB05630|Sodium stibogluconate TOP1 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34449:[DB05630 DB00906] DB05630|Sodium stibogluconate TOP1 DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1 34450:[DB05630 DB00743] DB05630|Sodium stibogluconate TOP1 DB00743|Gadobenic acid ALB common genes common pathways 34451:[DB05630 DB08811] DB05630|Sodium stibogluconate TOP1 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0042493| response to drug PDE3A;TOP1 34452:[DB05630 DB01092] DB05630|Sodium stibogluconate TOP1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1;CYP1A1;ATP1A3 34453:[DB05630 DB01077] DB05630|Sodium stibogluconate TOP1 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 34454:[DB05630 DB03255] DB05630|Sodium stibogluconate TOP1 DB03255|Phenol cobT;ALB common genes common pathways 34455:[DB05630 DB00942] DB05630|Sodium stibogluconate TOP1 DB00942|Cycrimine CHRM1 common genes common pathways 34456:[DB05630 DB08860] DB05630|Sodium stibogluconate TOP1 DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;ABCC2;ABCB1 GO:0016032| viral reproduction TOP1;SLC10A1 34457:[DB05630 DB12010] DB05630|Sodium stibogluconate TOP1 DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0016310| phosphorylation MUSK;MAP2K6;LCK;STK10;COQ8B;KDR;EPHA6;TESK1;PIK3C2B;MAPK10;CHEK2;YES1;LIMK1;RIPK4;GSK3A;RPS6KA6;RPS6KA1;DDR1;MARK2;PAK5;PRKCD;JAK2;MINK1;PLK2;PHKG1;MYLK3;EPHA7;FLT4;PTK2;NUAK2;TNNI3K;PDPK1;FER;PKN1;CASK;MERTK;ITK;DAPK2;TNIK;KIT;CSF1R;MYLK2;MAPKAPK5;CDK16;STK33;PRKCI;AAK1;GSK3B;NUAK1;MAP2K5;TAOK2;CDKL2;CLK3;MST1R;DAPK3;ERBB2;MAPK15;MAP3K2;CAMK1G;CDK4;AXL;STK16;NEK2;PRKG2;TGFBR2;JAK3;MARK3;ACVR1B;STK38L;DAPK1;ULK3;ICK;CAMK2G;MAST1;FGFR1;LTK;MAP3K19;EGFR;PDGFRA;TLK1;STK36;MAP3K10;NEK9;RIOK2;MAP4K2;DCLK3;DCLK2;PTK2B;TYRO3;BMP2K;AURKC;HIPK2;CSNK1A1;MYLK;RIOK1;IRAK4;PIP4K2C;PIP4K2B;SYK;TAOK3;STK38;PAK1;ZAP70;MYO3A;MAP3K6;HCK;PRPF4B;INSRR;MAP3K11;CHEK1;SRC;TTK;RET;OXSR1;EIF2AK2;TYK2;MAP4K3;SBK1;RIPK1;DYRK1B;PRKCG;TOP1;TNK1;EIF2AK1;ALK;DYRK1A;PLK4;RAF1;FLT1;ACVR1;CAMK2B;CDKL1;PIM1;PAK6;PRKACA;PI4KB;IKBKB;PAK3;IRAK3;ANKK1;MAP3K9;TSSK1B;PRKCQ;NEK3;EPHA5;SRMS;MAP3K12;ULK2;NIM1K;MKNK2;GAK;PRKAA1;NEK11;BRAF;STK24;MARK1;MAP3K3;SNRK;CAMKK2;MAPK7;ROS1;SIK2;SBK3;PIM3;MARK4;SLK;STK17B;MTOR;STK3;LATS1;PLK3;EPHA3;PRKACB;NEK4;BMX;ERN1;IRAK1;TAOK1;BMPR2;NTRK2;WEE1;RPS6KA3;PRKAA2;PDGFRB;MAPK14;DCLK1;PIK3CG;PAK2;EPHA8;NEK1;MATK;EPHB1;MAPK4;SGK3;BTK;CAMK2A;AURKA;STK26;TBK1;BMPR1B;TEC;LIMK2;TGFBR1;PLK1;FGFR2;EPHA4;MAP3K4;CSNK2A1;MAP3K13;PTK6;HIPK3;TNK2;CAMK1D;EIF2AK4;FGR;MAPK9;MAP4K1;CLK2;STK17A;JAK1;SIK3;MAP3K15;TEK;TIE1;CSK;PRKD1;FRK;ULK1;ABL1;RIOK3;AURKB;MELK;EPHB2;CSNK2A2;STK39;INSR;MKNK1;FGFR3;CAMKK1;TLK2;PIK3CD;CLK4;CDC42BPG;PKMYT1;NTRK1;EPHB4;MAP4K4;EPHA2;TXK;LYN;NTRK3;NEK5;ROCK2;MAPK13;FYN;RIPK2;MAP3K1;CDK17;CIT;MYLK4;STK32A;MAP2K3;MAP2K2;SIK1;IKBKE;COQ8A;CAMK1;LRRK2;CLK1;CDK1;BLK;MET;STK35;PIK3C2G;PAK4;ERBB4;ABL2;FLT3;MAP4K5;CAMK2D;FES;CDK15;PKN2;DDR2;PRKCE;EPHA1 GO:0018105| peptidyl-serine phosphorylation STK38;SYK;CSNK1A1;HIPK2;DCLK2;DCLK3;MAP3K10;IKBKB;PRKACA;CAMK2B;DYRK1A;TOP1;PRKCG;SBK1;TTK;SRC;PKN1;PDPK1;MYLK3;PLK2;PHKG1;PRKCD;CHEK2;MAST1;CAMK2G;STK38L;TGFBR2;CAMK1G;DAPK3;GSK3B;PRKCI;STK33;MAPKAPK5;MYLK2;DAPK2;MAPK13;TLK2;CAMKK1;MKNK1;STK39;ULK1;PRKD1;PRKCE;PKN2;CAMK2D;CDK1;CLK1;LRRK2;IKBKE;STK32A;MYLK4;PAK2;DCLK1;MAPK14;RPS6KA3;MTOR;MAPK7;CAMKK2;MKNK2;MAP3K12;PRKCQ;MAP4K1;MAPK9;CAMK1D;HIPK3;PLK1;TGFBR1;TBK1;CAMK2A;SGK3 GO:0016032| viral reproduction EIF2AK2;RIPK1;HCK;SRC;TOP1;DYRK1A;PDGFRA;SYK;TYRO3;AXL;LCK;KDR;EPHA2;LYN;FYN;TBK1;EIF2AK4;IRAK1;PAK2 GO:0006260| DNA replication CHEK1;TOP1;CDK1 GO:0012501| programmed cell death STK17B;RIPK1;TOP1 GO:0048511| rhythmic process CSNK2A1;MAPK9;PRKAA2;PRKAA1;SIK1;ROCK2;GSK3B;MAPK10;TOP1;PRKCG GO:0007059| chromosome segregation TOP1;NEK2;RIOK3;TLK2 GO:0007623| circadian rhythm TOP1;DYRK1A;EGFR;GSK3B;CDK4;NTRK3;NTRK1;NTRK2 GO:0016925| protein sumoylation TOP1;AURKB GO:0042493| response to drug NTRK1;LYN;FYN;CDK1;LCK;MAP2K6;ABCG2;UGT1A1;CDK4;TGFBR2;PTK2B;RET;SRC;TOP1 34458:[DB05630 DB14533] DB05630|Sodium stibogluconate TOP1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0016032| viral reproduction APOA2;MDM2;CFH;HDAC1;TP53;TP73;TOP1;IDE;SIVA1 GO:0016310| phosphorylation NME1;TOP1 GO:0042493| response to drug HDAC4;APOA2;MDM2;MGMT;TP73;HDAC1;TP53;SOD1;TOP1;APOA1;NME1 GO:0016925| protein sumoylation MDM2;TOP1 GO:0032922| circadian regulation of gene expression HDAC1;TOP1 GO:0006338| chromatin remodeling HDAC4;ESR1;HDAC1;TOP1 GO:0048511| rhythmic process TOP1;HDAC1;TP53 GO:0012501| programmed cell death TOP1;TP53 34459:[DB05630 DB00690] DB05630|Sodium stibogluconate TOP1 DB00690|Flurazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP2E1;CYP2A6;CYP3A4;ABCB1;SLC22A2 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;ABCB1;GABRG3 34460:[DB05630 DB04816] DB05630|Sodium stibogluconate TOP1 DB04816|Dantron ALB common genes common pathways 34461:[DB05630 DB04846] DB05630|Sodium stibogluconate TOP1 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways 34462:[DB05630 DB01698] DB05630|Sodium stibogluconate TOP1 DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways 34463:[DB05630 DB01791] DB05630|Sodium stibogluconate TOP1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways 34464:[DB05630 DB00896] DB05630|Sodium stibogluconate TOP1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 34465:[DB05630 DB00967] DB05630|Sodium stibogluconate TOP1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;TOP1 34466:[DB05630 DB06789] DB05630|Sodium stibogluconate TOP1 DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways 34467:[DB05630 DB11827] DB05630|Sodium stibogluconate TOP1 DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;TOP1 34468:[DB05630 DB00584] DB05630|Sodium stibogluconate TOP1 DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34469:[DB05630 DB00485] DB05630|Sodium stibogluconate TOP1 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways 34470:[DB05630 DB12070] DB05630|Sodium stibogluconate TOP1 DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways GO:0042493| response to drug UGT1A1;ABCG2;TOP1;ABCB1;ABCC2 34471:[DB05630 DB06705] DB05630|Sodium stibogluconate TOP1 DB06705|Gadofosveset trisodium ALB common genes common pathways 34472:[DB05630 DB00520] DB05630|Sodium stibogluconate TOP1 DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34473:[DB05630 DB05708] DB05630|Sodium stibogluconate TOP1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;CYP1A2 34474:[DB05630 DB00383] DB05630|Sodium stibogluconate TOP1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways 34475:[DB05630 DB00616] DB05630|Sodium stibogluconate TOP1 DB00616|Candoxatril MME;ACE common genes common pathways 34476:[DB05630 DB00180] DB05630|Sodium stibogluconate TOP1 DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34477:[DB05630 DB08960] DB05630|Sodium stibogluconate TOP1 DB08960|Hexamethonium CHRNA2 common genes common pathways 34478:[DB05630 DB06147] DB05630|Sodium stibogluconate TOP1 DB06147|Sulfathiazole CYP19A1 common genes common pathways 34479:[DB05630 DB13136] DB05630|Sodium stibogluconate TOP1 DB13136|Fluindione CYP2C9;CYP3A4 common genes common pathways 34480:[DB05630 DB06716] DB05630|Sodium stibogluconate TOP1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways 34481:[DB05630 DB11855] DB05630|Sodium stibogluconate TOP1 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;TOP1;ABCB1 34482:[DB05630 DB00641] DB05630|Sodium stibogluconate TOP1 DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0042493| response to drug UGT1A1;TOP1;ABCB1;ABCC2 34483:[DB05630 DB12515] DB05630|Sodium stibogluconate TOP1 DB12515|9-aminocamptothecin CYP3A4 common genes common pathways 34484:[DB05630 DB01497] DB05630|Sodium stibogluconate TOP1 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways 34485:[DB05630 DB00264] DB05630|Sodium stibogluconate TOP1 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34486:[DB05630 DB05253] DB05630|Sodium stibogluconate TOP1 DB05253|Proellex PGR common genes common pathways 34487:[DB05630 DB00523] DB05630|Sodium stibogluconate TOP1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0016032| viral reproduction RXRA;TOP1 34488:[DB05630 DB00259] DB05630|Sodium stibogluconate TOP1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 34489:[DB05630 DB00683] DB05630|Sodium stibogluconate TOP1 DB00683|Midazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRB1;GABRB3;GABRB2;GABRA6;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP4B1;UGT1A4;CYP2E1;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;GABRG3;CYP2E1;TOP1 34490:[DB05630 DB00306] DB05630|Sodium stibogluconate TOP1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;TOP1 34491:[DB05630 DB00288] DB05630|Sodium stibogluconate TOP1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0042493| response to drug ANXA1;TOP1 GO:0007059| chromosome segregation NR3C1;TOP1 34492:[DB05630 DB00279] DB05630|Sodium stibogluconate TOP1 DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0016032| viral reproduction SLC10A1;TOP1 GO:0006260| DNA replication PCNA;TOP1 GO:0042493| response to drug TOP1;ABCB1 GO:0016925| protein sumoylation PCNA;TOP1 34493:[DB05630 DB04975] DB05630|Sodium stibogluconate TOP1 DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0007059| chromosome segregation TOP2A;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0042493| response to drug CYP1A1;TOP1 GO:0048511| rhythmic process TOP2A;TOP1 GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP1 34494:[DB05630 DB00818] DB05630|Sodium stibogluconate TOP1 DB00818|Propofol GABRB2;GABRB3;SCN4A;SCN2A;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP2B6;UGT1A8;UGT1A9;UGT1A1;FAAH;CYP2E1;CYP1B1;CYP1A1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;UGT1A6;ALB common genes common pathways GO:0042493| response to drug UGT1A1;CYP1A1;TOP1;CYP2E1;GABRG3;CYP1A2 34495:[DB05630 DB00636] DB05630|Sodium stibogluconate TOP1 DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0048511| rhythmic process TOP1;PPARA GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0042493| response to drug CYP1A1;CYP2E1;TOP1 34496:[DB05630 DB05115] DB05630|Sodium stibogluconate TOP1 DB05115|NN344 INSR common genes common pathways GO:0016310| phosphorylation TOP1;INSR 34497:[DB05630 DB06042] DB05630|Sodium stibogluconate TOP1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways GO:0048511| rhythmic process TOP2A;TOP1 GO:0007059| chromosome segregation TOP2A;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A;TOP2B GO:0006265| DNA topological change TOP2A;TOP1;TOP2B GO:0040016| embryonic cleavage TOP1;TOP2A 34498:[DB05630 DB14724] DB05630|Sodium stibogluconate TOP1 DB14724|Emapalumab IFNG common genes common pathways 34499:[DB05630 DB03425] DB05630|Sodium stibogluconate TOP1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways 34500:[DB05630 DB00750] DB05630|Sodium stibogluconate TOP1 DB00750|Prilocaine SCN5A common genes common pathways 34501:[DB05630 DB05849] DB05630|Sodium stibogluconate TOP1 DB05849|NCX 950 ADRB2 common genes common pathways 34502:[DB05630 DB04445] DB05630|Sodium stibogluconate TOP1 DB04445|Mercuric iodide SULT2A1 common genes common pathways 34503:[DB05630 DB12923] DB05630|Sodium stibogluconate TOP1 DB12923|Gallopamil CYP3A4 common genes common pathways 34504:[DB05630 DB04934] DB05630|Sodium stibogluconate TOP1 DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways 34505:[DB05630 DB00751] DB05630|Sodium stibogluconate TOP1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0007623| circadian rhythm HTR7;TOP1 GO:0042493| response to drug TOP1;HTR2A;ADRA1A;ABCB1 34506:[DB05630 DB08972] DB05630|Sodium stibogluconate TOP1 DB08972|Flumequine CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34507:[DB05630 DB00765] DB05630|Sodium stibogluconate TOP1 DB00765|Metyrosine TH common genes common pathways GO:0042493| response to drug TH;TOP1 34508:[DB05630 DB05824] DB05630|Sodium stibogluconate TOP1 DB05824|CNS-5161 GRIN1 common genes common pathways 34509:[DB05630 DB01109] DB05630|Sodium stibogluconate TOP1 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0016310| phosphorylation FGFR2;FGFR4;FGFR1;TOP1 34510:[DB05630 DB00805] DB05630|Sodium stibogluconate TOP1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0006260| DNA replication ACHE;TOP1 GO:0016310| phosphorylation TOP1;HTR2B GO:0042493| response to drug SLC6A4;HTR2C;HTR2B;DRD2;DRD1;TOP1;HTR2A GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0007623| circadian rhythm SLC6A4;TOP1 34511:[DB05630 DB06201] DB05630|Sodium stibogluconate TOP1 DB06201|Rufinamide GRM5;SCN9A;CES1;CYP2E1;CYP3A4;ALB common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 34512:[DB05630 DB00199] DB05630|Sodium stibogluconate TOP1 DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;CYP1A2 34513:[DB05630 DB00374] DB05630|Sodium stibogluconate TOP1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways 34514:[DB05630 DB00958] DB05630|Sodium stibogluconate TOP1 DB00958|Carboplatin XDH;MPO;GSTT1;MT1A;MT2A;SOD1;GSTP1;GSTM1;NQO1;SLC31A1;SLC31A2;ATP7A;ATP7B;ABCG2;ABCC2 common genes common pathways GO:0042493| response to drug ABCG2;TOP1;SOD1;ABCC2 34515:[DB05630 DB04880] DB05630|Sodium stibogluconate TOP1 DB04880|Enoximone PDE3A common genes common pathways GO:0042493| response to drug PDE3A;TOP1 34516:[DB05630 DB12007] DB05630|Sodium stibogluconate TOP1 DB12007|Isoflavone PPARA;PPARG common genes common pathways GO:0048511| rhythmic process TOP1;PPARG;PPARA GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug TOP1;PPARG 34517:[DB05630 DB00947] DB05630|Sodium stibogluconate TOP1 DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1 GO:0006338| chromatin remodeling ESR1;TOP1 34518:[DB05630 DB08899] DB05630|Sodium stibogluconate TOP1 DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34519:[DB05630 DB01134] DB05630|Sodium stibogluconate TOP1 DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways 34520:[DB05630 DB00527] DB05630|Sodium stibogluconate TOP1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0042493| response to drug TOP1;BCHE 34521:[DB05630 DB00253] DB05630|Sodium stibogluconate TOP1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34522:[DB05630 DB01323] DB05630|Sodium stibogluconate TOP1 DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34523:[DB05630 DB06781] DB05630|Sodium stibogluconate TOP1 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 34524:[DB05630 DB00939] DB05630|Sodium stibogluconate TOP1 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34525:[DB05630 DB01892] DB05630|Sodium stibogluconate TOP1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCC2;TOP1 34526:[DB05630 DB06823] DB05630|Sodium stibogluconate TOP1 DB06823|Tiopronin MPO common genes common pathways 34527:[DB05630 DB00369] DB05630|Sodium stibogluconate TOP1 DB00369|Cidofovir TYMP;SLC22A6 common genes common pathways 34528:[DB05630 DB06804] DB05630|Sodium stibogluconate TOP1 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34529:[DB05630 DB00969] DB05630|Sodium stibogluconate TOP1 DB00969|Alosetron HTR3A;CYP2C9;CYP3A4;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;CYP1A2 34530:[DB05630 DB12131] DB05630|Sodium stibogluconate TOP1 DB12131|Vinpocetine CYP3A4 common genes common pathways 34531:[DB05630 DB00826] DB05630|Sodium stibogluconate TOP1 DB00826|Natamycin CYP3A4 common genes common pathways 34532:[DB05630 DB04820] DB05630|Sodium stibogluconate TOP1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0042493| response to drug COMT;TOP1;MAOB 34533:[DB05630 DB06754] DB05630|Sodium stibogluconate TOP1 DB06754|Danaparoid SERPINC1 common genes common pathways 34534:[DB05630 DB13346] DB05630|Sodium stibogluconate TOP1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34535:[DB05630 DB11742] DB05630|Sodium stibogluconate TOP1 DB11742|Ebastine CYP3A4 common genes common pathways 34536:[DB05630 DB04920] DB05630|Sodium stibogluconate TOP1 DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways GO:0042493| response to drug BCHE;TOP1;CYP2E1 34537:[DB05630 DB06742] DB05630|Sodium stibogluconate TOP1 DB06742|Ambroxol CYP3A4 common genes common pathways 34538:[DB05630 DB03546] DB05630|Sodium stibogluconate TOP1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 34539:[DB05630 DB00325] DB05630|Sodium stibogluconate TOP1 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A1 34540:[DB05630 DB06218] DB05630|Sodium stibogluconate TOP1 DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways 34541:[DB05630 DB01006] DB05630|Sodium stibogluconate TOP1 DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways 34542:[DB05630 DB01378] DB05630|Sodium stibogluconate TOP1 DB01378|Magnesium cation ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 34543:[DB05630 DB13931] DB05630|Sodium stibogluconate TOP1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:0048511| rhythmic process TOP1;ROCK2 GO:0016310| phosphorylation ROCK1;TOP1;ROCK2 34544:[DB05630 DB07879] DB05630|Sodium stibogluconate TOP1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0042493| response to drug HDAC4;TOP1 GO:0006338| chromatin remodeling HDAC4;TOP1 34545:[DB05630 DB07453] DB05630|Sodium stibogluconate TOP1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34546:[DB05630 DB00257] DB05630|Sodium stibogluconate TOP1 DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1;ABCC2;ABCB1 34547:[DB05630 DB03747] DB05630|Sodium stibogluconate TOP1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways 34548:[DB05630 DB06819] DB05630|Sodium stibogluconate TOP1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways 34549:[DB05630 DB08865] DB05630|Sodium stibogluconate TOP1 DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0016310| phosphorylation ALK;TOP1;MET 34550:[DB05630 DB00602] DB05630|Sodium stibogluconate TOP1 DB00602|Ivermectin GLRA3;GABRB3;CYP3A4;ABCB1;ABCC1;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;ABCC1;ABCC2;ABCB1 34551:[DB05630 DB00155] DB05630|Sodium stibogluconate TOP1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0006338| chromatin remodeling TOP1;PADI4 GO:0007623| circadian rhythm TOP1;NOS2;ASS1 GO:0042493| response to drug TOP1;OTC 34552:[DB05630 DB08813] DB05630|Sodium stibogluconate TOP1 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0006338| chromatin remodeling MYC;TOP1 GO:0042493| response to drug TOP1;MYC;FOS 34553:[DB05630 DB09082] DB05630|Sodium stibogluconate TOP1 DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways 34554:[DB05630 DB00055] DB05630|Sodium stibogluconate TOP1 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0007623| circadian rhythm TOP1;SERPINE1 34555:[DB05630 DB01359] DB05630|Sodium stibogluconate TOP1 DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0042493| response to drug TOP1;HTR1B 34556:[DB05630 DB00281] DB05630|Sodium stibogluconate TOP1 DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0007623| circadian rhythm EGFR;TOP1 GO:0042493| response to drug TOP1;ABCB1;CYP1A2 GO:0016310| phosphorylation EGFR;TOP1 34557:[DB05630 DB00524] DB05630|Sodium stibogluconate TOP1 DB00524|Metolazone SLC12A3 common genes common pathways 34558:[DB05630 DB01110] DB05630|Sodium stibogluconate TOP1 DB01110|Miconazole NOS3;NOS2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;KCNH2;KCNH6;KCNH7;NR1I2;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP11B1;CYP51A1;CYP19A1;ABCB1 common genes common pathways GO:0007623| circadian rhythm TOP1;NOS2 GO:0042493| response to drug CYP2E1;TOP1;ABCB1 34559:[DB05630 DB07992] DB05630|Sodium stibogluconate TOP1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways 34560:[DB05630 DB04884] DB05630|Sodium stibogluconate TOP1 DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug TOP1;HTR2C;HTR1B 34561:[DB05630 DB13981] DB05630|Sodium stibogluconate TOP1 DB13981|Nomegestrol acetate CYP3A4 common genes common pathways 34562:[DB05630 DB09017] DB05630|Sodium stibogluconate TOP1 DB09017|Brotizolam CYP3A4 common genes common pathways 34563:[DB05630 DB09087] DB05630|Sodium stibogluconate TOP1 DB09087|Potassium alum ALB common genes common pathways 34564:[DB05630 DB09121] DB05630|Sodium stibogluconate TOP1 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug TOP1;ADCY1 GO:0007623| circadian rhythm ADCY1;TOP1 GO:0048511| rhythmic process ADCY1;TOP1 34565:[DB05630 DB03010] DB05630|Sodium stibogluconate TOP1 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 34566:[DB05630 DB00323] DB05630|Sodium stibogluconate TOP1 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways GO:0042493| response to drug COMT;TOP1 34567:[DB05630 DB00924] DB05630|Sodium stibogluconate TOP1 DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0042493| response to drug HTR2A;TOP1;UGT1A1;CYP1A2 GO:0016032| viral reproduction TOP1;HTR2A 34568:[DB05630 DB01591] DB05630|Sodium stibogluconate TOP1 DB01591|Solifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4 common genes common pathways 34569:[DB05630 DB13158] DB05630|Sodium stibogluconate TOP1 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34570:[DB05630 DB08893] DB05630|Sodium stibogluconate TOP1 DB08893|Mirabegron ADRB3;CYP3A4;CYP2D6;BCHE;ALB;ORM1;ABCB1;SLCO1A2 common genes common pathways GO:0042493| response to drug BCHE;ABCB1;TOP1 34571:[DB05630 DB05416] DB05630|Sodium stibogluconate TOP1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0048511| rhythmic process TOP1;PPARA 34572:[DB05630 DB06433] DB05630|Sodium stibogluconate TOP1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0006260| DNA replication TOP1;RRM1 34573:[DB05630 DB00548] DB05630|Sodium stibogluconate TOP1 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0042493| response to drug TOP1;SRD5A2 34574:[DB05630 DB06727] DB05630|Sodium stibogluconate TOP1 DB06727|Sparteine CYP2D6 common genes common pathways 34575:[DB05630 DB00406] DB05630|Sodium stibogluconate TOP1 DB00406|Gentian violet cation SLC22A1 common genes common pathways 34576:[DB05630 DB09401] DB05630|Sodium stibogluconate TOP1 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0042493| response to drug BCL2;TOP1 GO:0018105| peptidyl-serine phosphorylation BCL2;TOP1 34577:[DB05630 DB05309] DB05630|Sodium stibogluconate TOP1 DB05309|TP-508 FGF4 common genes common pathways 34578:[DB05630 DB12212] DB05630|Sodium stibogluconate TOP1 DB12212|Landiolol CYP2D6 common genes common pathways 34579:[DB05630 DB05050] DB05630|Sodium stibogluconate TOP1 DB05050|ADL5859 OPRD1 common genes common pathways 34580:[DB05630 DB07348] DB05630|Sodium stibogluconate TOP1 DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways 34581:[DB05630 DB00929] DB05630|Sodium stibogluconate TOP1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways 34582:[DB05630 DB01581] DB05630|Sodium stibogluconate TOP1 DB01581|Sulfamerazine ALB common genes common pathways 34583:[DB05630 DB07246] DB05630|Sodium stibogluconate TOP1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 34584:[DB05630 DB13385] DB05630|Sodium stibogluconate TOP1 DB13385|Dihydroergocryptine CYP3A4 common genes common pathways 34585:[DB05630 DB08810] DB05630|Sodium stibogluconate TOP1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0042493| response to drug HTR2A;TOP1 34586:[DB05630 DB01000] DB05630|Sodium stibogluconate TOP1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 34587:[DB05630 DB06154] DB05630|Sodium stibogluconate TOP1 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways 34588:[DB05630 DB06162] DB05630|Sodium stibogluconate TOP1 DB06162|Lumiliximab FCER2 common genes common pathways 34589:[DB05630 DB06268] DB05630|Sodium stibogluconate TOP1 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways 34590:[DB05630 DB09234] DB05630|Sodium stibogluconate TOP1 DB09234|Darodipine CYP3A4 common genes common pathways 34591:[DB05630 DB08916] DB05630|Sodium stibogluconate TOP1 DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways GO:0007623| circadian rhythm EGFR;TOP1 GO:0042493| response to drug TOP1;ABCG2;ABCB1 GO:0016310| phosphorylation EGFR;TOP1;ERBB2;ERBB4 34592:[DB05630 DB05787] DB05630|Sodium stibogluconate TOP1 DB05787|LM-609 ITGB3 common genes common pathways GO:0016032| viral reproduction TOP1;ITGB3 34593:[DB05630 DB08884] DB05630|Sodium stibogluconate TOP1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0042493| response to drug ABCC4;ABCC2;TOP1 34594:[DB05630 DB05458] DB05630|Sodium stibogluconate TOP1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways 34595:[DB05630 DB05109] DB05630|Sodium stibogluconate TOP1 DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 34596:[DB05630 DB01437] DB05630|Sodium stibogluconate TOP1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0042493| response to drug GABRG3;TOP1 34597:[DB05630 DB06778] DB05630|Sodium stibogluconate TOP1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes common pathways GO:0042493| response to drug MAOB;TOP1;SOD1;LOX 34598:[DB05630 DB06204] DB05630|Sodium stibogluconate TOP1 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0042493| response to drug SLC6A4;SLC6A2;TOP1 GO:0007623| circadian rhythm SLC6A4;TOP1 34599:[DB05630 DB09028] DB05630|Sodium stibogluconate TOP1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways 34600:[DB05630 DB00744] DB05630|Sodium stibogluconate TOP1 DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34601:[DB05630 DB00452] DB05630|Sodium stibogluconate TOP1 DB00452|Framycetin rpsL;CXCR4 common genes common pathways GO:0016032| viral reproduction CXCR4;TOP1 34602:[DB05630 DB00937] DB05630|Sodium stibogluconate TOP1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A3;TOP1;SLC6A2 34603:[DB05630 DB13191] DB05630|Sodium stibogluconate TOP1 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways GO:0016310| phosphorylation TOP1;CKMT2;CKMT1A;CKB;CKM 34604:[DB05630 DB06186] DB05630|Sodium stibogluconate TOP1 DB06186|Ipilimumab CTLA4 common genes common pathways 34605:[DB05630 DB00247] DB05630|Sodium stibogluconate TOP1 DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0016310| phosphorylation TOP1;HTR2B GO:0016032| viral reproduction HTR2A;TOP1 GO:0007623| circadian rhythm TOP1;HTR7 GO:0042493| response to drug HTR2C;HTR1B;TOP1;HTR2A;HTR2B 34606:[DB05630 DB03515] DB05630|Sodium stibogluconate TOP1 DB03515|Equilenin CYP3A4 common genes common pathways 34607:[DB05630 DB05260] DB05630|Sodium stibogluconate TOP1 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0006260| DNA replication RRM2;TOP1 GO:0016032| viral reproduction TOP1;TFRC 34608:[DB05630 DB04977] DB05630|Sodium stibogluconate TOP1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 34609:[DB05630 DB01239] DB05630|Sodium stibogluconate TOP1 DB01239|Chlorprothixene DRD2;DRD1;DRD3;HTR2A;HTR2B;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ABCB1 common genes common pathways GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction TOP1;HTR2A GO:0042493| response to drug ABCB1;DRD3;HTR2C;HTR2B;DRD2;DRD1;TOP1;HTR2A GO:0032922| circadian regulation of gene expression DRD2;TOP1;DRD3 34610:[DB05630 DB00724] DB05630|Sodium stibogluconate TOP1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways 34611:[DB05630 DB06271] DB05630|Sodium stibogluconate TOP1 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 34612:[DB05630 DB00367] DB05630|Sodium stibogluconate TOP1 DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 GO:0042493| response to drug SRD5A1;TOP1 34613:[DB05630 DB00364] DB05630|Sodium stibogluconate TOP1 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways GO:0006260| DNA replication EGF;TOP1 34614:[DB05630 DB13956] DB05630|Sodium stibogluconate TOP1 DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0016032| viral reproduction TOP1;BECN1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process NCOA2;TOP1 GO:0007623| circadian rhythm NCOA2;TOP1 GO:0032922| circadian regulation of gene expression TOP1;NCOA2 GO:0042493| response to drug ABCG2;UGT1A1;TOP1;CYP1A1;BECN1;ABCB1;CYP1A2 34615:[DB05630 DB00875] DB05630|Sodium stibogluconate TOP1 DB00875|Flupentixol DRD2;HTR2A;DRD1;ADRA1A;CHRM1;DDC;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0007623| circadian rhythm DDC;TOP1 GO:0042493| response to drug ABCB1;ADRA1A;DRD2;TOP1;HTR2A;DRD1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 34616:[DB05630 DB01193] DB05630|Sodium stibogluconate TOP1 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34617:[DB05630 DB01624] DB05630|Sodium stibogluconate TOP1 DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug DRD2;ADRA1A;TOP1;HTR2A;DRD1 GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0016032| viral reproduction TOP1;HTR2A 34618:[DB05630 DB03552] DB05630|Sodium stibogluconate TOP1 DB03552|3-Tyrosine TH common genes common pathways GO:0042493| response to drug TOP1;TH 34619:[DB05630 DB00171] DB05630|Sodium stibogluconate TOP1 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0048511| rhythmic process TOP1;CSNK2A1;PRKAA1;ADCY1 GO:0042493| response to drug ABCC8;ABCC9;ABCC1;TOP1;ABCC6;ABCA1;ABCC2;ADCY1;ABCB1;ABCC4;ACSL1 GO:0007623| circadian rhythm ASS1;ADCY1;TOP1 GO:0016310| phosphorylation ABL1;CDK15;ABL2;PRKAA1;CSNK2A1;TNK2;ACVRL1;ALK;AMHR2;TOP1;ACVR1;NT5C2;PIK3CA;ARAF;AKT1;ACVR1B;ADK GO:0016032| viral reproduction SLC25A4;TOP1 GO:0018105| peptidyl-serine phosphorylation AKT1;TOP1 34620:[DB05630 DB05766] DB05630|Sodium stibogluconate TOP1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;TOP1;DRD3 GO:0042493| response to drug DRD2;TOP1;DRD3 34621:[DB05630 DB08883] DB05630|Sodium stibogluconate TOP1 DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34622:[DB05630 DB00352] DB05630|Sodium stibogluconate TOP1 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0042493| response to drug TOP1;ABCC4 34623:[DB05630 DB00445] DB05630|Sodium stibogluconate TOP1 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes common pathways GO:0006265| DNA topological change TOP1;TOP2A GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006338| chromatin remodeling TOP1;CHD1 GO:0048511| rhythmic process TOP2A;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0042493| response to drug TOP1;ABCC1 GO:0016925| protein sumoylation TOP1;TOP2A 34624:[DB05630 DB09066] DB05630|Sodium stibogluconate TOP1 DB09066|Corifollitropin alfa FSHR common genes common pathways 34625:[DB05630 DB06738] DB05630|Sodium stibogluconate TOP1 DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0042493| response to drug TOP1;GRIN2A 34626:[DB05630 DB09215] DB05630|Sodium stibogluconate TOP1 DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34627:[DB05630 DB05223] DB05630|Sodium stibogluconate TOP1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0048511| rhythmic process HDAC2;TOP1;HDAC1 GO:0006338| chromatin remodeling HDAC2;TOP1;HDAC1 GO:0032922| circadian regulation of gene expression TOP1;HDAC1;HDAC2 GO:0042493| response to drug HDAC1;TOP1;HDAC2 GO:0007623| circadian rhythm HDAC3;TOP1 GO:0016032| viral reproduction TOP1;HDAC1 34628:[DB05630 DB12698] DB05630|Sodium stibogluconate TOP1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0016032| viral reproduction CCR5;CD4;CXCR4;TOP1 34629:[DB05630 DB01597] DB05630|Sodium stibogluconate TOP1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways 34630:[DB05630 DB00031] DB05630|Sodium stibogluconate TOP1 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0042493| response to drug TOP1;CALR GO:0007623| circadian rhythm TOP1;SERPINE1 GO:0016032| viral reproduction KRT8;TOP1 34631:[DB05630 DB00642] DB05630|Sodium stibogluconate TOP1 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways GO:0007623| circadian rhythm TYMS;TOP1 GO:0042493| response to drug TYMS;TOP1 GO:0016310| phosphorylation DCK;TOP1 34632:[DB05630 DB09027] DB05630|Sodium stibogluconate TOP1 DB09027|Ledipasvir ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;ABCB1 34633:[DB05630 DB02187] DB05630|Sodium stibogluconate TOP1 DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 34634:[DB05630 DB01207] DB05630|Sodium stibogluconate TOP1 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0042493| response to drug TBXA2R;TOP1 34635:[DB05630 DB00043] DB05630|Sodium stibogluconate TOP1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways 34636:[DB05630 DB01194] DB05630|Sodium stibogluconate TOP1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways 34637:[DB05630 DB09343] DB05630|Sodium stibogluconate TOP1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways 34638:[DB05630 DB00240] DB05630|Sodium stibogluconate TOP1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34639:[DB05630 DB00954] DB05630|Sodium stibogluconate TOP1 DB00954|Dirithromycin CYP3A4 common genes common pathways 34640:[DB05630 DB06600] DB05630|Sodium stibogluconate TOP1 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34641:[DB05630 DB08910] DB05630|Sodium stibogluconate TOP1 DB08910|Pomalidomide CRBN;TNF;PTGS2;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;TOP1 34642:[DB05630 DB00860] DB05630|Sodium stibogluconate TOP1 DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0007059| chromosome segregation NR3C1;TOP1 34643:[DB05630 DB06176] DB05630|Sodium stibogluconate TOP1 DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes common pathways GO:0006338| chromatin remodeling HDAC4;HDAC1;TOP1;HDAC2 GO:0048511| rhythmic process TOP1;HDAC1;HDAC2 GO:0032922| circadian regulation of gene expression TOP1;HDAC1;HDAC2 GO:0042493| response to drug CYP1A1;HDAC1;TOP1;ABCC1;HDAC2;HDAC4;ABCB1 GO:0016032| viral reproduction HDAC1;TOP1 34644:[DB05630 DB00846] DB05630|Sodium stibogluconate TOP1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34645:[DB05630 DB06209] DB05630|Sodium stibogluconate TOP1 DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes common pathways 34646:[DB05630 DB01125] DB05630|Sodium stibogluconate TOP1 DB01125|Anisindione GGCX common genes common pathways 34647:[DB05630 DB00748] DB05630|Sodium stibogluconate TOP1 DB00748|Carbinoxamine HRH1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 34648:[DB05630 DB01606] DB05630|Sodium stibogluconate TOP1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways 34649:[DB05630 DB00360] DB05630|Sodium stibogluconate TOP1 DB00360|Sapropterin PAH;NOS3;TH;TPH1;PTGS2 common genes common pathways GO:0007623| circadian rhythm TOP1;TPH1 GO:0042493| response to drug PTGS2;TH;TOP1 34650:[DB05630 DB00851] DB05630|Sodium stibogluconate TOP1 DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0006260| DNA replication POLA2;TOP1 GO:0042493| response to drug TOP1;CYP2E1;CYP1A1;CYP1A2 34651:[DB05630 DB00481] DB05630|Sodium stibogluconate TOP1 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0042493| response to drug TOP1;UGT1A1 34652:[DB05630 DB01009] DB05630|Sodium stibogluconate TOP1 DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0042493| response to drug ABCC4;PTGS2;UGT1A1;TOP1 34653:[DB05630 DB01536] DB05630|Sodium stibogluconate TOP1 DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways 34654:[DB05630 DB12095] DB05630|Sodium stibogluconate TOP1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0007623| circadian rhythm TPH1;TPH2;TOP1 34655:[DB05630 DB08806] DB05630|Sodium stibogluconate TOP1 DB08806|Roxatidine acetate HRH2 common genes common pathways 34656:[DB05630 DB12498] DB05630|Sodium stibogluconate TOP1 DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0016032| viral reproduction TOP1;CXCR4 34657:[DB05630 DB11967] DB05630|Sodium stibogluconate TOP1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0042493| response to drug UGT1A1;TOP1;CYP1A2 GO:0016310| phosphorylation MAP3K1;MAP2K2;TOP1 34658:[DB05630 DB00629] DB05630|Sodium stibogluconate TOP1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34659:[DB05630 DB01632] DB05630|Sodium stibogluconate TOP1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0016032| viral reproduction UCKL1;TOP1 GO:0016310| phosphorylation TOP1;UCKL1 34660:[DB05630 DB00562] DB05630|Sodium stibogluconate TOP1 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways GO:0042493| response to drug TOP1;CA9 34661:[DB05630 DB05812] DB05630|Sodium stibogluconate TOP1 DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes common pathways GO:0042493| response to drug TOP1;ABCC1;CYP1A2 34662:[DB05630 DB01370] DB05630|Sodium stibogluconate TOP1 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 34663:[DB05630 DB01114] DB05630|Sodium stibogluconate TOP1 DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0042493| response to drug TOP1;SLC6A3;SLC6A2;SLC6A4 GO:0007623| circadian rhythm SLC6A4;TOP1 34664:[DB05630 DB08905] DB05630|Sodium stibogluconate TOP1 DB08905|Formestane CYP3A4 common genes common pathways 34665:[DB05630 DB00054] DB05630|Sodium stibogluconate TOP1 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:0016032| viral reproduction FCGR2B;TOP1;ITGB3 34666:[DB05630 DB01277] DB05630|Sodium stibogluconate TOP1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0016310| phosphorylation INSR;IGF1R;TOP1 34667:[DB05630 DB00461] DB05630|Sodium stibogluconate TOP1 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2;CYP1A2 34668:[DB05630 DB02746] DB05630|Sodium stibogluconate TOP1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0048511| rhythmic process TOP1;PPARG;PPARA GO:0042493| response to drug PPARG;TOP1 GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0016032| viral reproduction RXRA;TOP1 34669:[DB05630 DB14060] DB05630|Sodium stibogluconate TOP1 DB14060|NS-398 PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34670:[DB05630 DB00005] DB05630|Sodium stibogluconate TOP1 DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0042493| response to drug TOP1;LTA GO:0016032| viral reproduction FCGR2B;TOP1 34671:[DB05630 DB01180] DB05630|Sodium stibogluconate TOP1 DB01180|Rescinnamine ACE common genes common pathways 34672:[DB05630 DB00310] DB05630|Sodium stibogluconate TOP1 DB00310|Chlorthalidone SLC12A1 common genes common pathways 34673:[DB05630 DB00216] DB05630|Sodium stibogluconate TOP1 DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0016310| phosphorylation HTR2B;TOP1 GO:0007623| circadian rhythm TOP1;HTR7 GO:0042493| response to drug ABCB1;HTR1B;HTR2B;TOP1 34674:[DB05630 DB00975] DB05630|Sodium stibogluconate TOP1 DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCC4;ABCB1;TOP1;ADA 34675:[DB05630 DB00528] DB05630|Sodium stibogluconate TOP1 DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways 34676:[DB05630 DB12537] DB05630|Sodium stibogluconate TOP1 DB12537|Benzodiazepine CYP3A4 common genes common pathways 34677:[DB05630 DB12589] DB05630|Sodium stibogluconate TOP1 DB12589|Dacetuzumab CD40 common genes common pathways 34678:[DB05630 DB04886] DB05630|Sodium stibogluconate TOP1 DB04886|Calanolide A CYP3A4 common genes common pathways 34679:[DB05630 DB07615] DB05630|Sodium stibogluconate TOP1 DB07615|Tranilast HPGDS;CYP3A4;CYP2C9 common genes common pathways 34680:[DB05630 DB05075] DB05630|Sodium stibogluconate TOP1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0016032| viral reproduction KDR;TOP1 GO:0016310| phosphorylation FLT4;KDR;TOP1;FLT1;CSK 34681:[DB05630 DB05095] DB05630|Sodium stibogluconate TOP1 DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34682:[DB05630 DB01100] DB05630|Sodium stibogluconate TOP1 DB01100|Pimozide DRD2;DRD3;KCNH2;CALM1;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;DRD2;DRD3;ABCB1;CYP1A2 GO:0032922| circadian regulation of gene expression DRD3;TOP1;DRD2 34683:[DB05630 DB00067] DB05630|Sodium stibogluconate TOP1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;ABCC2 34684:[DB05630 DB00983] DB05630|Sodium stibogluconate TOP1 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways 34685:[DB05630 DB02902] DB05630|Sodium stibogluconate TOP1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways 34686:[DB05630 DB00789] DB05630|Sodium stibogluconate TOP1 DB00789|Gadopentetic acid PGD common genes common pathways 34687:[DB05630 DB04599] DB05630|Sodium stibogluconate TOP1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug HTR2A;TOP1;DRD2 GO:0016032| viral reproduction TOP1;HTR2A 34688:[DB05630 DB01667] DB05630|Sodium stibogluconate TOP1 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0042493| response to drug PNP;CYP1A2;TOP1 34689:[DB05630 DB00282] DB05630|Sodium stibogluconate TOP1 DB00282|Pamidronate FDPS common genes common pathways GO:0016032| viral reproduction TOP1;FDPS 34690:[DB05630 DB00935] DB05630|Sodium stibogluconate TOP1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 34691:[DB05630 DB01341] DB05630|Sodium stibogluconate TOP1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways 34692:[DB05630 DB00763] DB05630|Sodium stibogluconate TOP1 DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;TOP1 34693:[DB05630 DB08868] DB05630|Sodium stibogluconate TOP1 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0048511| rhythmic process HDAC1;TOP1 GO:0006338| chromatin remodeling HDAC1;TOP1 GO:0042493| response to drug HDAC1;CYP2E1;TOP1 GO:0032922| circadian regulation of gene expression TOP1;HDAC1 GO:0016310| phosphorylation SPHK1;TOP1 GO:0016032| viral reproduction TOP1;HDAC1 34694:[DB05630 DB09274] DB05630|Sodium stibogluconate TOP1 DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways 34695:[DB05630 DB00575] DB05630|Sodium stibogluconate TOP1 DB00575|Clonidine ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP3A5;SLC22A3;SLC22A5;SLC22A4;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;TOP1;ADRA1A;CYP1A1 34696:[DB05630 DB11919] DB05630|Sodium stibogluconate TOP1 DB11919|6-O-benzylguanine CYP3A4 common genes common pathways 34697:[DB05630 DB08907] DB05630|Sodium stibogluconate TOP1 DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;ABCC2 34698:[DB05630 DB12248] DB05630|Sodium stibogluconate TOP1 DB12248|Tulobuterol ADRB2 common genes common pathways 34699:[DB05630 DB11575] DB05630|Sodium stibogluconate TOP1 DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34700:[DB05630 DB08881] DB05630|Sodium stibogluconate TOP1 DB08881|Vemurafenib BRAF;CYP1A2;CYP2D6;CYP3A4;CYP2C9;CYP2C8;CYP2B6;ALB;ORM1;ABCC1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCC1;ABCG2;TOP1 GO:0016310| phosphorylation BRAF;TOP1 34701:[DB05630 DB11327] DB05630|Sodium stibogluconate TOP1 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 GO:0007623| circadian rhythm NOS2;TOP1 34702:[DB05630 DB14542] DB05630|Sodium stibogluconate TOP1 DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0042493| response to drug ANXA1;HSD11B2;ABCB1;TOP1;ABCG2 GO:0007059| chromosome segregation TOP1;NR3C1 34703:[DB05630 DB00626] DB05630|Sodium stibogluconate TOP1 DB00626|Bacitracin IDE;A2M common genes common pathways GO:0016032| viral reproduction IDE;TOP1 34704:[DB05630 DB00541] DB05630|Sodium stibogluconate TOP1 DB00541|Vincristine TUBB;TUBA4A;CYP3A5;CYP3A7;CYP3A4;ABCB1;ABCC3;SLC22A3;ABCC1;ABCC10;ABCC2;ABCB11;ABCG2;RALBP1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC1;ABCG2;TOP1;ABCC2;ABCB1 34705:[DB05630 DB11574] DB05630|Sodium stibogluconate TOP1 DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34706:[DB05630 DB00583] DB05630|Sodium stibogluconate TOP1 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0042493| response to drug CPT1A;TOP1 GO:0007623| circadian rhythm CPT1A;TOP1 34707:[DB05630 DB05212] DB05630|Sodium stibogluconate TOP1 DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways GO:0048511| rhythmic process NFKB2;TOP1 34708:[DB05630 DB11828] DB05630|Sodium stibogluconate TOP1 DB11828|Neratinib EGFR;CYP3A4;FMO3;ALB;ORM1;ORM2;ABCB1 common genes common pathways GO:0007623| circadian rhythm EGFR;TOP1 GO:0042493| response to drug ABCB1;TOP1 GO:0016310| phosphorylation EGFR;TOP1 34709:[DB05630 DB05281] DB05630|Sodium stibogluconate TOP1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0042493| response to drug TOP1;BCL2 GO:0018105| peptidyl-serine phosphorylation TOP1;BCL2 34710:[DB05630 DB00158] DB05630|Sodium stibogluconate TOP1 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0042493| response to drug MTHFR;ABCC4;TOP1;GGH;CYP2E1;ABCG2 34711:[DB05630 DB03554] DB05630|Sodium stibogluconate TOP1 DB03554|5-Iodouracil DPYD common genes common pathways 34712:[DB05630 DB04356] DB05630|Sodium stibogluconate TOP1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34713:[DB05630 DB00901] DB05630|Sodium stibogluconate TOP1 DB00901|Bitolterol ADRB2 common genes common pathways 34714:[DB05630 DB00692] DB05630|Sodium stibogluconate TOP1 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ADRA1A;TOP1 34715:[DB05630 DB01041] DB05630|Sodium stibogluconate TOP1 DB01041|Thalidomide CRBN;TNF;NFKB1;FGFR2;PTGS2;ORM1;ORM2;CYP2C19;CYP1A1;CYP2E1;CYP2C9;PTGS1;PTGS2;CYP3A5 common genes common pathways GO:0042493| response to drug PTGS2;CYP2E1;TOP1;CYP1A1 GO:0016310| phosphorylation TOP1;FGFR2 34716:[DB05630 DB01303] DB05630|Sodium stibogluconate TOP1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0006338| chromatin remodeling TOP1;HDAC2 GO:0048511| rhythmic process TOP1;HDAC2 GO:0042493| response to drug CYP1A2;PDE3A;TOP1;ADORA2A;HDAC2 GO:0032922| circadian regulation of gene expression TOP1;HDAC2 34717:[DB05630 DB08341] DB05630|Sodium stibogluconate TOP1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0042493| response to drug TOP1;PTK2B GO:0016310| phosphorylation TOP1;PTK2B 34718:[DB05630 DB13627] DB05630|Sodium stibogluconate TOP1 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34719:[DB05630 DB00234] DB05630|Sodium stibogluconate TOP1 DB00234|Reboxetine SLC6A2;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1;SLC6A2 34720:[DB05630 DB00535] DB05630|Sodium stibogluconate TOP1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 34721:[DB05630 DB05481] DB05630|Sodium stibogluconate TOP1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways 34722:[DB05630 DB13456] DB05630|Sodium stibogluconate TOP1 DB13456|Midecamycin CYP3A4 common genes common pathways 34723:[DB05630 DB11799] DB05630|Sodium stibogluconate TOP1 DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0042493| response to drug UGT1A1;TOP1 34724:[DB05630 DB00025] DB05630|Sodium stibogluconate TOP1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0042493| response to drug CALR;TOP1 34725:[DB05630 DB12329] DB05630|Sodium stibogluconate TOP1 DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways 34726:[DB05630 DB01365] DB05630|Sodium stibogluconate TOP1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 34727:[DB05630 DB09211] DB05630|Sodium stibogluconate TOP1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways 34728:[DB05630 DB01011] DB05630|Sodium stibogluconate TOP1 DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 34729:[DB05630 DB00219] DB05630|Sodium stibogluconate TOP1 DB00219|Oxyphenonium CHRM1 common genes common pathways 34730:[DB05630 DB13928] DB05630|Sodium stibogluconate TOP1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug LPL;TOP1 34731:[DB05630 DB06771] DB05630|Sodium stibogluconate TOP1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34732:[DB05630 DB06800] DB05630|Sodium stibogluconate TOP1 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways 34733:[DB05630 DB13139] DB05630|Sodium stibogluconate TOP1 DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways 34734:[DB05630 DB01152] DB05630|Sodium stibogluconate TOP1 DB01152|Candicidin CYP3A4 common genes common pathways 34735:[DB05630 DB00313] DB05630|Sodium stibogluconate TOP1 DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes common pathways GO:0032922| circadian regulation of gene expression HDAC2;TOP1;PPARA GO:0042493| response to drug SCN11A;PPARG;ABAT;CYP1A2;HDAC2;UGT1A1;TOP1 GO:0048511| rhythmic process PPARA;PPARG;TOP1;HDAC2 GO:0006338| chromatin remodeling HDAC2;TOP1 34736:[DB05630 DB00354] DB05630|Sodium stibogluconate TOP1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways 34737:[DB05630 DB00476] DB05630|Sodium stibogluconate TOP1 DB00476|Duloxetine SLC6A4;SLC6A2;SLC6A3;CYP1A2;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug SLC6A2;SLC6A3;TOP1;SLC6A4;CYP1A2 GO:0007623| circadian rhythm TOP1;SLC6A4 34738:[DB05630 DB11963] DB05630|Sodium stibogluconate TOP1 DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1;ABCG2;ABCB1 GO:0007623| circadian rhythm EGFR;TOP1 GO:0016310| phosphorylation EGFR;TOP1 34739:[DB05630 DB00586] DB05630|Sodium stibogluconate TOP1 DB00586|Diclofenac PTGS2;PTGS1;ALOX5;SCN4A;ASIC1;KCNQ2;KCNQ3;PLA2G2A;CYP2C9;CYP2C19;CYP1A2;CYP2C8;UGT1A1;UGT2B7;PTGS1;CYP3A4;CYP1A1;CYP2B6;CYP2C18;CYP2E1;TTR;ALB;ABCC4;ABCB1;ABCC1;SLC22A6;SLC22A8;SLCO1C1;SLC22A11;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;ABCC4;PTGS2;UGT1A1;ABCC1;TOP1;CYP2E1;CYP1A1 34740:[DB05630 DB14512] DB05630|Sodium stibogluconate TOP1 DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 34741:[DB05630 DB00185] DB05630|Sodium stibogluconate TOP1 DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways 34742:[DB05630 DB01419] DB05630|Sodium stibogluconate TOP1 DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34743:[DB05630 DB09123] DB05630|Sodium stibogluconate TOP1 DB09123|Dienogest PGR;AR;CYP3A4 common genes common pathways 34744:[DB05630 DB00887] DB05630|Sodium stibogluconate TOP1 DB00887|Bumetanide SLC12A1;SLC12A2;SLC12A4;SLC12A5;CFTR;PTGS2;SLC10A1;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO1A2 common genes common pathways GO:0016032| viral reproduction SLC10A1;TOP1 GO:0042493| response to drug PTGS2;TOP1;SLC12A5 34745:[DB05630 DB09325] DB05630|Sodium stibogluconate TOP1 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 34746:[DB05630 DB00115] DB05630|Sodium stibogluconate TOP1 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0042493| response to drug MTHFR;TOP1 34747:[DB05630 DB06626] DB05630|Sodium stibogluconate TOP1 DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug UGT1A1;TOP1;ABCB1;CYP1A2 GO:0016032| viral reproduction KDR;TOP1 GO:0016310| phosphorylation TOP1;FLT1;KDR;FLT4 34748:[DB05630 DB05562] DB05630|Sodium stibogluconate TOP1 DB05562|Naluzotan HTR1A common genes common pathways 34749:[DB05630 DB06454] DB05630|Sodium stibogluconate TOP1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0042493| response to drug TOP1;DRD2;DRD3 34750:[DB05630 DB14126] DB05630|Sodium stibogluconate TOP1 DB14126|Tenofovir ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34751:[DB05630 DB00677] DB05630|Sodium stibogluconate TOP1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0006260| DNA replication TOP1;ACHE GO:0042493| response to drug BCHE;TOP1 34752:[DB05630 DB00136] DB05630|Sodium stibogluconate TOP1 DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways 34753:[DB05630 DB00776] DB05630|Sodium stibogluconate TOP1 DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1;ABCB1 34754:[DB05630 DB11323] DB05630|Sodium stibogluconate TOP1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34755:[DB05630 DB14544] DB05630|Sodium stibogluconate TOP1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug ABCG2;TOP1;ABCB1;ANXA1;HSD11B2 34756:[DB05630 DB14481] DB05630|Sodium stibogluconate TOP1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0042493| response to drug SLC8A1;TOP1;CALR;SLC34A1 GO:0016032| viral reproduction SLC20A2;TOP1 34757:[DB05630 DB09308] DB05630|Sodium stibogluconate TOP1 DB09308|Solithromycin CYP3A4 common genes common pathways 34758:[DB05630 DB08927] DB05630|Sodium stibogluconate TOP1 DB08927|Amperozide HTR2A common genes common pathways GO:0042493| response to drug HTR2A;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 34759:[DB05630 DB00017] DB05630|Sodium stibogluconate TOP1 DB00017|Salmon Calcitonin CALCR common genes common pathways 34760:[DB05630 DB05266] DB05630|Sodium stibogluconate TOP1 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0042493| response to drug TOP1;PDE3A 34761:[DB05630 DB13757] DB05630|Sodium stibogluconate TOP1 DB13757|Epanolol CYP2D6 common genes common pathways 34762:[DB05630 DB01071] DB05630|Sodium stibogluconate TOP1 DB01071|Mequitazine HRH1;CYP2D6;CYP3A4 common genes common pathways 34763:[DB05630 DB01427] DB05630|Sodium stibogluconate TOP1 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0042493| response to drug TOP1;PDE3A 34764:[DB05630 DB00349] DB05630|Sodium stibogluconate TOP1 DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;SLC6A11;GABRG3;ABCB1 34765:[DB05630 DB05229] DB05630|Sodium stibogluconate TOP1 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways 34766:[DB05630 DB05488] DB05630|Sodium stibogluconate TOP1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 GO:0016925| protein sumoylation TOP1;TOP2B GO:0006265| DNA topological change TOP1;TOP2B 34767:[DB05630 DB01394] DB05630|Sodium stibogluconate TOP1 DB01394|Colchicine TUBB1;TUBB;CYP3A4;CYP2B6;CYP2C8;CYP2E1;ABCB4;SLC22A3;ABCB1;ABCC1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;CYP2E1;TOP1;ABCB4 GO:0007623| circadian rhythm ABCB4;TOP1 34768:[DB05630 DB14541] DB05630|Sodium stibogluconate TOP1 DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug TOP1;ABCG2;ANXA1;HSD11B2;ABCB1 34769:[DB05630 DB01037] DB05630|Sodium stibogluconate TOP1 DB01037|Selegiline MAOB;MAOA;CYP2B6;CYP3A4;CYP2A6;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;CYP2E1;TOP1;MAOB 34770:[DB05630 DB00927] DB05630|Sodium stibogluconate TOP1 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways 34771:[DB05630 DB09006] DB05630|Sodium stibogluconate TOP1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug TOP1;PPARG GO:0048511| rhythmic process PPARA;PPARG;TOP1 34772:[DB05630 DB01268] DB05630|Sodium stibogluconate TOP1 DB01268|Sunitinib PDGFRB;FLT1;KIT;KDR;FLT4;FLT3;CSF1R;PDGFRA;CYP3A5;CYP3A7;CYP3A4;ABCC4;ABCB1;ABCC2;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;TOP1;ABCC2;ABCB1;ABCC4 GO:0016032| viral reproduction TOP1;PDGFRA;KDR GO:0016310| phosphorylation TOP1;FLT1;PDGFRA;CSF1R;KIT;KDR;FLT4;FLT3;PDGFRB 34773:[DB05630 DB00979] DB05630|Sodium stibogluconate TOP1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0042493| response to drug TOP1;BCHE 34774:[DB05630 DB00363] DB05630|Sodium stibogluconate TOP1 DB00363|Clozapine DRD2;HTR2A;DRD1;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;HRH4;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALY;GSTP1;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2C19;CYP2A6;CYP2C8;FMO3;UGT1A4;CYP2E1;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0032922| circadian regulation of gene expression DRD3;TOP1;DRD2 GO:0042493| response to drug DRD1;CYP2E1;HTR2A;TOP1;ADRA1A;DRD2;CYP1A1;HTR1B;ABCB1;DRD3;CYP1A2;HTR2C GO:0007623| circadian rhythm HTR7;TOP1 GO:0048511| rhythmic process TOP1;DRD4 34775:[DB05630 DB07577] DB05630|Sodium stibogluconate TOP1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug TYMS;TOP1 GO:0007623| circadian rhythm TYMS;TOP1 34776:[DB05630 DB09318] DB05630|Sodium stibogluconate TOP1 DB09318|Synthetic Conjugated Estrogens, B ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 34777:[DB05630 DB00928] DB05630|Sodium stibogluconate TOP1 DB00928|Azacitidine DNMT1;CDA common genes common pathways 34778:[DB05630 DB08734] DB05630|Sodium stibogluconate TOP1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug TOP1;TYMS GO:0007623| circadian rhythm TYMS;TOP1 34779:[DB05630 DB09116] DB05630|Sodium stibogluconate TOP1 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0042493| response to drug TOP1;CAT 34780:[DB05630 DB09347] DB05630|Sodium stibogluconate TOP1 DB09347|Acetrizoic acid ALB common genes common pathways 34781:[DB05630 DB05029] DB05630|Sodium stibogluconate TOP1 DB05029|Lancovutide PLA2G4A common genes common pathways 34782:[DB05630 DB00564] DB05630|Sodium stibogluconate TOP1 DB00564|Carbamazepine SCN5A;CHRNA4;CHRNB2;NR1I2;CYP3A4;CYP2C8;CYP1A2;CYP2C9;CYP2C19;CYP2B6;CYP3A5;CYP3A7;UGT2B7;UGT1A1;ABCB1;RALBP1;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1;CYP1A2;ABCC2;ABCB1 34783:[DB05630 DB00262] DB05630|Sodium stibogluconate TOP1 DB00262|Carmustine GSR;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34784:[DB05630 DB13520] DB05630|Sodium stibogluconate TOP1 DB13520|Metergoline SCN2A common genes common pathways 34785:[DB05630 DB14019] DB05630|Sodium stibogluconate TOP1 DB14019|Fosnetupitant CYP3A4 common genes common pathways 34786:[DB05630 DB09059] DB05630|Sodium stibogluconate TOP1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0042493| response to drug TOP1;OXTR 34787:[DB05630 DB08805] DB05630|Sodium stibogluconate TOP1 DB08805|Metiamide HRH2 common genes common pathways 34788:[DB05630 DB01454] DB05630|Sodium stibogluconate TOP1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug SLC6A4;HTR2C;SLC6A2;HTR2B;SLC6A3;HTR2A;TOP1 GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 34789:[DB05630 DB00204] DB05630|Sodium stibogluconate TOP1 DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways 34790:[DB05630 DB05459] DB05630|Sodium stibogluconate TOP1 DB05459|Briakinumab IL12B;IL23A common genes common pathways 34791:[DB05630 DB00813] DB05630|Sodium stibogluconate TOP1 DB00813|Fentanyl OPRM1;OPRD1;OPRK1;ABCB1;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34792:[DB05630 DB13003] DB05630|Sodium stibogluconate TOP1 DB13003|Cortivazol NR3C1 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34793:[DB05630 DB00914] DB05630|Sodium stibogluconate TOP1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0016310| phosphorylation TOP1;PRKAA1 GO:0048511| rhythmic process PRKAA1;TOP1 34794:[DB05630 DB01956] DB05630|Sodium stibogluconate TOP1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0042493| response to drug GABRG3;TOP1 34795:[DB05630 DB00469] DB05630|Sodium stibogluconate TOP1 DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34796:[DB05630 DB00620] DB05630|Sodium stibogluconate TOP1 DB00620|Triamcinolone NR3C1;CYP3A4;PTGS2;BCHE;SERPINA6 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 GO:0042493| response to drug TOP1;PTGS2;BCHE 34797:[DB05630 DB00454] DB05630|Sodium stibogluconate TOP1 DB00454|Meperidine OPRK1;GRIN1;GRIN2B;GRIN2A;GRIN2C;GRIN2D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;OPRM1;SLC6A3;SLC6A2;SLC6A4;CES1;CYP3A4;CYP2C19;CYP2B6;CYP2D6;CYP1A2;ALB;ORM1 common genes common pathways GO:0042493| response to drug SLC6A2;TOP1;SLC6A3;GRIN2A;SLC6A4;CYP1A2 GO:0007623| circadian rhythm TOP1;SLC6A4 34798:[DB05630 DB00489] DB05630|Sodium stibogluconate TOP1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways 34799:[DB05630 DB01015] DB05630|Sodium stibogluconate TOP1 DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes common pathways 34800:[DB05630 DB00321] DB05630|Sodium stibogluconate TOP1 DB00321|Amitriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;OPRD1;OPRK1;NTRK1;NTRK2;ADRA1A;ADRA1D;ADRA2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCNQ2;KCNA1;KCND2;KCND3;HRH2;HRH4;SIGMAR1;HTR2C;ADRA1B;HTR7;HTR1D;OPRM1;HTR1B;HTR6;KCNQ3;ADRB1;ADRB2;ADRB3;CYP2D6;CYP1A2;CYP2C19;CYP2C9;CYP3A4;CYP3A5;CYP2B6;CYP2C8;CYP2E1;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0007623| circadian rhythm NTRK2;HTR7;SLC6A4;NTRK1;TOP1 GO:0042493| response to drug CYP2E1;HTR2A;TOP1;ADRA1A;UGT1A1;SLC6A2;CYP1A2;HTR2C;NTRK1;SLC6A4;ABCB1;HTR1B GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation TOP1;NTRK2;NTRK1 34801:[DB05630 DB02261] DB05630|Sodium stibogluconate TOP1 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34802:[DB05630 DB00248] DB05630|Sodium stibogluconate TOP1 DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0048511| rhythmic process DRD4;TOP1 GO:0007623| circadian rhythm HTR7;TOP1 GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0042493| response to drug HTR2B;ADRA1A;DRD2;HTR2A;TOP1;DRD1;DRD3;HTR1B;ABCB1;HTR2C GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction HTR2A;TOP1 34803:[DB05630 DB00209] DB05630|Sodium stibogluconate TOP1 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways 34804:[DB05630 DB00730] DB05630|Sodium stibogluconate TOP1 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1;CYP1A2 34805:[DB05630 DB04978] DB05630|Sodium stibogluconate TOP1 DB04978|SP1049C TOP2A common genes common pathways GO:0048511| rhythmic process TOP1;TOP2A GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP1 GO:0040016| embryonic cleavage TOP2A;TOP1 34806:[DB05630 DB05205] DB05630|Sodium stibogluconate TOP1 DB05205|CX157 MAOA common genes common pathways 34807:[DB05630 DB00359] DB05630|Sodium stibogluconate TOP1 DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 34808:[DB05630 DB00761] DB05630|Sodium stibogluconate TOP1 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0042493| response to drug SLC12A5;TOP1 34809:[DB05630 DB01028] DB05630|Sodium stibogluconate TOP1 DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;MT-ND1;GABRG3;CYP1A2 34810:[DB05630 DB11714] DB05630|Sodium stibogluconate TOP1 DB11714|Durvalumab CD274;CD80 common genes common pathways GO:0016032| viral reproduction TOP1;CD80 34811:[DB05630 DB14025] DB05630|Sodium stibogluconate TOP1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34812:[DB05630 DB14634] DB05630|Sodium stibogluconate TOP1 DB14634|Fluprednidene acetate CYP3A4 common genes common pathways 34813:[DB05630 DB04690] DB05630|Sodium stibogluconate TOP1 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes TOP1 common pathways GO:0016310| phosphorylation TOP1 GO:0006265| DNA topological change TOP1 GO:0018105| peptidyl-serine phosphorylation TOP1 GO:0006260| DNA replication TOP1 GO:0040016| embryonic cleavage TOP1 GO:0016032| viral reproduction TOP1 GO:0006338| chromatin remodeling TOP1 GO:0048511| rhythmic process TOP1 GO:0012501| programmed cell death TOP1 GO:0007059| chromosome segregation TOP1 GO:0007623| circadian rhythm TOP1 GO:0032922| circadian regulation of gene expression TOP1 GO:0016925| protein sumoylation TOP1 GO:0042493| response to drug TOP1;ABCG2;ABCB1 34814:[DB05630 DB02486] DB05630|Sodium stibogluconate TOP1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways 34815:[DB05630 DB06543] DB05630|Sodium stibogluconate TOP1 DB06543|Astaxanthin NFKBIA common genes common pathways GO:0016032| viral reproduction TOP1;NFKBIA 34816:[DB05630 DB00154] DB05630|Sodium stibogluconate TOP1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34817:[DB05630 DB12278] DB05630|Sodium stibogluconate TOP1 DB12278|Propiverine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CACNA1C;ADRA1A;CYP3A4;FMO1;FMO3;CYP2B common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 34818:[DB05630 DB00221] DB05630|Sodium stibogluconate TOP1 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways 34819:[DB05630 DB05227] DB05630|Sodium stibogluconate TOP1 DB05227|APD791 HTR2A common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0042493| response to drug HTR2A;TOP1 34820:[DB05630 DB08908] DB05630|Sodium stibogluconate TOP1 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0042493| response to drug RELA;TOP1 GO:0016032| viral reproduction TOP1;RELA 34821:[DB05630 DB05104] DB05630|Sodium stibogluconate TOP1 DB05104|Asimadoline OPRK1 common genes common pathways 34822:[DB05630 DB09071] DB05630|Sodium stibogluconate TOP1 DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0007623| circadian rhythm MTNR1A;MTNR1B;TOP1 GO:0042493| response to drug TOP1;CYP1A2 34823:[DB05630 DB00712] DB05630|Sodium stibogluconate TOP1 DB00712|Flurbiprofen PTGS1;PTGS2;CYP2C9;UGT2B7;UGT1A1;UGT1A3;UGT1A9;UGT2B4;ALB;ABCC4;SLC22A6 common genes common pathways GO:0042493| response to drug PTGS2;UGT1A1;TOP1;ABCC4 34824:[DB05630 DB05706] DB05630|Sodium stibogluconate TOP1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways GO:0007059| chromosome segregation TOP1;TOP2A GO:0016925| protein sumoylation TOP1;TOP2A GO:0048511| rhythmic process TOP2A;TOP1 GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP2A;TOP1 34825:[DB05630 DB04487] DB05630|Sodium stibogluconate TOP1 DB04487|N-Methylleucine CXCL10 common genes common pathways 34826:[DB05630 DB02123] DB05630|Sodium stibogluconate TOP1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction TOP1;SLC10A1 34827:[DB05630 DB06335] DB05630|Sodium stibogluconate TOP1 DB06335|Saxagliptin DPP4;CYP3A4;CYP3A5;ABCC1;SLCO4C1;SLC22A8 common genes common pathways GO:0042493| response to drug ABCC1;TOP1 34828:[DB05630 DB00817] DB05630|Sodium stibogluconate TOP1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34829:[DB05630 DB09076] DB05630|Sodium stibogluconate TOP1 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34830:[DB05630 DB00665] DB05630|Sodium stibogluconate TOP1 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0042493| response to drug TOP1;POR 34831:[DB05630 DB00977] DB05630|Sodium stibogluconate TOP1 DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0016032| viral reproduction TOP1;SLC10A1 GO:0042493| response to drug UGT1A1;TOP1;ABCB1;ABCC2 GO:0006338| chromatin remodeling TOP1;ESR1 34832:[DB05630 DB00246] DB05630|Sodium stibogluconate TOP1 DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0048511| rhythmic process DRD4;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1;DRD3 GO:0042493| response to drug HTR2C;CYP1A2;HTR1B;DRD3;DRD2;ADRA1A;DRD1;HTR2A;TOP1 GO:0007623| circadian rhythm HTR7;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 34833:[DB05630 DB00907] DB05630|Sodium stibogluconate TOP1 DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0042493| response to drug TOP1;SLC6A3;SLC6A2;BCHE;SLC6A4;SCN11A GO:0007623| circadian rhythm SLC6A4;TOP1 34834:[DB05630 DB00605] DB05630|Sodium stibogluconate TOP1 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0016310| phosphorylation TOP1;MAPK3 GO:0018105| peptidyl-serine phosphorylation TOP1;MAPK3 GO:0016032| viral reproduction MAPK3;TOP1 GO:0042493| response to drug CYP1A1;TOP1;PTGS2 34835:[DB05630 DB05187] DB05630|Sodium stibogluconate TOP1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0048511| rhythmic process TOP1;PPARA;PPARG GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug PPARG;TOP1 34836:[DB05630 DB05838] DB05630|Sodium stibogluconate TOP1 DB05838|OPC-51803 AVPR2 common genes common pathways 34837:[DB05630 DB01355] DB05630|Sodium stibogluconate TOP1 DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 34838:[DB05630 DB06080] DB05630|Sodium stibogluconate TOP1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0016032| viral reproduction KDR;TOP1 GO:0016310| phosphorylation TOP1;FLT1;KDR;FLT4;CSF1R;KIT;FLT3 34839:[DB05630 DB00651] DB05630|Sodium stibogluconate TOP1 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0042493| response to drug TOP1;ADORA2A 34840:[DB05630 DB06230] DB05630|Sodium stibogluconate TOP1 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways 34841:[DB05630 DB11182] DB05630|Sodium stibogluconate TOP1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways 34842:[DB05630 DB00457] DB05630|Sodium stibogluconate TOP1 DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;CYP1A1;ADRA1A;TOP1 34843:[DB05630 DB09048] DB05630|Sodium stibogluconate TOP1 DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways 34844:[DB05630 DB14007] DB05630|Sodium stibogluconate TOP1 DB14007|Pentetic acid SERPINA1 common genes common pathways 34845:[DB05630 DB02527] DB05630|Sodium stibogluconate TOP1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0042493| response to drug ABCC4;TOP1 34846:[DB05630 DB09216] DB05630|Sodium stibogluconate TOP1 DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34847:[DB05630 DB00820] DB05630|Sodium stibogluconate TOP1 DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways 34848:[DB05630 DB07954] DB05630|Sodium stibogluconate TOP1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways 34849:[DB05630 DB11363] DB05630|Sodium stibogluconate TOP1 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;TOP1 GO:0016310| phosphorylation ALK;TOP1 34850:[DB05630 DB08889] DB05630|Sodium stibogluconate TOP1 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0016032| viral reproduction PSMB8;PSMB2;TOP1;PSMB1;PSMB10;PSMB9;PSMB5 34851:[DB05630 DB11605] DB05630|Sodium stibogluconate TOP1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0048511| rhythmic process TOP1;PPARA 34852:[DB05630 DB08602] DB05630|Sodium stibogluconate TOP1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways 34853:[DB05630 DB00687] DB05630|Sodium stibogluconate TOP1 DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 34854:[DB05630 DB09301] DB05630|Sodium stibogluconate TOP1 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways 34855:[DB05630 DB01137] DB05630|Sodium stibogluconate TOP1 DB01137|Levofloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;ABCB1;SLC22A6;SLC22A2;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0016925| protein sumoylation TOP2A;TOP1 GO:0042493| response to drug TOP1;ABCB1;CYP1A2 GO:0007059| chromosome segregation TOP2A;TOP1 GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP1;TOP2A 34856:[DB05630 DB00876] DB05630|Sodium stibogluconate TOP1 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0042493| response to drug TOP1;ABCC2 34857:[DB05630 DB01544] DB05630|Sodium stibogluconate TOP1 DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0042493| response to drug UGT1A1;CYP2E1;TOP1;TSPO 34858:[DB05630 DB05316] DB05630|Sodium stibogluconate TOP1 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;DRD2 GO:0042493| response to drug HTR2A;TOP1;DRD2 GO:0016032| viral reproduction HTR2A;TOP1 34859:[DB05630 DB01414] DB05630|Sodium stibogluconate TOP1 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways 34860:[DB05630 DB01192] DB05630|Sodium stibogluconate TOP1 DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways 34861:[DB05630 DB00339] DB05630|Sodium stibogluconate TOP1 DB00339|Pyrazinamide XDH;AOX1;CYP3A4 common genes common pathways 34862:[DB05630 DB04743] DB05630|Sodium stibogluconate TOP1 DB04743|Nimesulide PTGS2;PLA2G2E;LTF;CYP3A4 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34863:[DB05630 DB04714] DB05630|Sodium stibogluconate TOP1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0016032| viral reproduction TOP1;FDPS 34864:[DB05630 DB09477] DB05630|Sodium stibogluconate TOP1 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways 34865:[DB05630 DB08795] DB05630|Sodium stibogluconate TOP1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways 34866:[DB05630 DB09240] DB05630|Sodium stibogluconate TOP1 DB09240|Niludipine CYP3A4 common genes common pathways 34867:[DB05630 DB13421] DB05630|Sodium stibogluconate TOP1 DB13421|Edoxudine ALB common genes common pathways 34868:[DB05630 DB12023] DB05630|Sodium stibogluconate TOP1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways 34869:[DB05630 DB13879] DB05630|Sodium stibogluconate TOP1 DB13879|Glecaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1;ABCG2;ABCB1 34870:[DB05630 DB05423] DB05630|Sodium stibogluconate TOP1 DB05423|ORG-34517 NR3C1 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 34871:[DB05630 DB05415] DB05630|Sodium stibogluconate TOP1 DB05415|OSI-461 PDE5A common genes common pathways 34872:[DB05630 DB00571] DB05630|Sodium stibogluconate TOP1 DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A1;HTR1B;ABCB1;CYP1A2 34873:[DB05630 DB04076] DB05630|Sodium stibogluconate TOP1 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;PNP;CYP1A2 34874:[DB05630 DB05971] DB05630|Sodium stibogluconate TOP1 DB05971|Archexin AKT1 common genes common pathways GO:0016310| phosphorylation TOP1;AKT1 GO:0018105| peptidyl-serine phosphorylation AKT1;TOP1 34875:[DB05630 DB12629] DB05630|Sodium stibogluconate TOP1 DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways 34876:[DB05630 DB06240] DB05630|Sodium stibogluconate TOP1 DB06240|Tariquidar ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34877:[DB05630 DB00806] DB05630|Sodium stibogluconate TOP1 DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;ADORA2A;CYP1A2 34878:[DB05630 DB01273] DB05630|Sodium stibogluconate TOP1 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways 34879:[DB05630 DB07447] DB05630|Sodium stibogluconate TOP1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways 34880:[DB05630 DB08729] DB05630|Sodium stibogluconate TOP1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways 34881:[DB05630 DB11752] DB05630|Sodium stibogluconate TOP1 DB11752|Bryostatin 1 CYP3A4 common genes common pathways 34882:[DB05630 DB00498] DB05630|Sodium stibogluconate TOP1 DB00498|Phenindione VKORC1 common genes common pathways 34883:[DB05630 DB08878] DB05630|Sodium stibogluconate TOP1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways 34884:[DB05630 DB14146] DB05630|Sodium stibogluconate TOP1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34885:[DB05630 DB14029] DB05630|Sodium stibogluconate TOP1 DB14029|Furafylline CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34886:[DB05630 DB00808] DB05630|Sodium stibogluconate TOP1 DB00808|Indapamide SLC12A3;CYP3A4 common genes common pathways 34887:[DB05630 DB09107] DB05630|Sodium stibogluconate TOP1 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways 34888:[DB05630 DB00159] DB05630|Sodium stibogluconate TOP1 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug PTGS2;TOP1;SLC8A1;PPARG GO:0048511| rhythmic process PPARA;PPARG;TOP1 34889:[DB05630 DB04903] DB05630|Sodium stibogluconate TOP1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways 34890:[DB05630 DB00727] DB05630|Sodium stibogluconate TOP1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways 34891:[DB05630 DB13014] DB05630|Sodium stibogluconate TOP1 DB13014|Hypericin GSTA1;GSTP1;ALB common genes common pathways 34892:[DB05630 DB00951] DB05630|Sodium stibogluconate TOP1 DB00951|Isoniazid katG;CYP2C8;CYP1A2;CYP3A4;CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2D6;CYP2C19;NAT2;CYP2A6;CYP2C8;ALB common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;TOP1 34893:[DB05630 DB00988] DB05630|Sodium stibogluconate TOP1 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0048511| rhythmic process TOP1;DRD4 GO:0007623| circadian rhythm TOP1;SLC6A4;HTR7 GO:0042493| response to drug COMT;SLC6A4;DRD3;DRD1;TOP1;SOD1;DRD2;SLC6A3;MAOB;SLC6A2 GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 34894:[DB05630 DB12742] DB05630|Sodium stibogluconate TOP1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0016032| viral reproduction PDGFRA;TOP1 GO:0016310| phosphorylation KIT;PDGFRA;RET;TOP1;FLT3;MET GO:0042493| response to drug RAD51;TOP1;RET 34895:[DB05630 DB00317] DB05630|Sodium stibogluconate TOP1 DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0016310| phosphorylation TOP1;EGFR GO:0007623| circadian rhythm TOP1;EGFR GO:0042493| response to drug CYP1A1;TOP1;ABCG2;ABCB1 34896:[DB05630 DB00433] DB05630|Sodium stibogluconate TOP1 DB00433|Prochlorperazine DRD2;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;DRD2 GO:0032922| circadian regulation of gene expression DRD2;TOP1 34897:[DB05630 DB01184] DB05630|Sodium stibogluconate TOP1 DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes common pathways GO:0032922| circadian regulation of gene expression DRD3;TOP1;DRD2 GO:0042493| response to drug DRD2;TOP1;ABCB1;DRD3;CYP1A2 34898:[DB05630 DB11915] DB05630|Sodium stibogluconate TOP1 DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways 34899:[DB05630 DB01579] DB05630|Sodium stibogluconate TOP1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0042493| response to drug TOP1;ADRA1A;SLC6A2 34900:[DB05630 DB05964] DB05630|Sodium stibogluconate TOP1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug SLC6A2;DRD2;TOP1;SLC6A4 GO:0007623| circadian rhythm SLC6A4;TOP1 34901:[DB05630 DB06663] DB05630|Sodium stibogluconate TOP1 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways 34902:[DB05630 DB00082] DB05630|Sodium stibogluconate TOP1 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0042493| response to drug TOP1;BCHE 34903:[DB05630 DB01861] DB05630|Sodium stibogluconate TOP1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 34904:[DB05630 DB04557] DB05630|Sodium stibogluconate TOP1 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes common pathways GO:0048511| rhythmic process PPARA;TOP1 GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0016032| viral reproduction TOP1;RXRA 34905:[DB05630 DB00870] DB05630|Sodium stibogluconate TOP1 DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes common pathways GO:0042493| response to drug PTGS2;UGT1A1;TOP1 34906:[DB05630 DB00028] DB05630|Sodium stibogluconate TOP1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:0016032| viral reproduction TOP1;FCGR2B 34907:[DB05630 DB06196] DB05630|Sodium stibogluconate TOP1 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways GO:0016032| viral reproduction ANPEP;TOP1 34908:[DB05630 DB01246] DB05630|Sodium stibogluconate TOP1 DB01246|Alimemazine HRH1;CYP3A4 common genes common pathways 34909:[DB05630 DB01442] DB05630|Sodium stibogluconate TOP1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug SLC6A4;MAOB;SLC6A3;HTR2A;TOP1;SLC6A2 GO:0016032| viral reproduction TOP1;HTR2A 34910:[DB05630 DB00899] DB05630|Sodium stibogluconate TOP1 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways 34911:[DB05630 DB00218] DB05630|Sodium stibogluconate TOP1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0007059| chromosome segregation TOP1;TOP2A GO:0042493| response to drug TOP1;CYP1A2 GO:0016925| protein sumoylation TOP2A;TOP1 GO:0048511| rhythmic process TOP2A;TOP1 GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP1;TOP2A 34912:[DB05630 DB13530] DB05630|Sodium stibogluconate TOP1 DB13530|Mepindolol CYP2D6 common genes common pathways 34913:[DB05630 DB05199] DB05630|Sodium stibogluconate TOP1 DB05199|LX1031 TPH1 common genes common pathways GO:0007623| circadian rhythm TOP1;TPH1 34914:[DB05630 DB01103] DB05630|Sodium stibogluconate TOP1 DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34915:[DB05630 DB13165] DB05630|Sodium stibogluconate TOP1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:0048511| rhythmic process TOP1;ROCK2 GO:0016310| phosphorylation TOP1;ROCK1;ROCK2 34916:[DB05630 DB03346] DB05630|Sodium stibogluconate TOP1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways 34917:[DB05630 DB00686] DB05630|Sodium stibogluconate TOP1 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways 34918:[DB05630 DB09093] DB05630|Sodium stibogluconate TOP1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways 34919:[DB05630 DB06203] DB05630|Sodium stibogluconate TOP1 DB06203|Alogliptin DPP4;CYP3A4;CYP2D6 common genes common pathways 34920:[DB05630 DB13443] DB05630|Sodium stibogluconate TOP1 DB13443|Esatenolol CYP2D6 common genes common pathways 34921:[DB05630 DB05642] DB05630|Sodium stibogluconate TOP1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0042493| response to drug TOP1;SLC6A2 34922:[DB05630 DB00245] DB05630|Sodium stibogluconate TOP1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0042493| response to drug TOP1;SLC6A3 34923:[DB05630 DB14070] DB05630|Sodium stibogluconate TOP1 DB14070|HM-30181 ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34924:[DB05630 DB03477] DB05630|Sodium stibogluconate TOP1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34925:[DB05630 DB00091] DB05630|Sodium stibogluconate TOP1 DB00091|Ciclosporin CAMLG;PPP3R2;PPIA;PPIF;CYP3A7;CYP3A5;CYP3A4;CYP2C19;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCC3;ABCB11;ABCC1;SLCO1A2;SLC10A2;SLC10A1;SLC22A6;ABCC10;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0016032| viral reproduction SLC10A1;PPIA;TOP1;CAMLG GO:0042493| response to drug TOP1;ABCC1;ABCG2;ABCC2;ABCB1 GO:0012501| programmed cell death PPIF;TOP1 34926:[DB05630 DB11156] DB05630|Sodium stibogluconate TOP1 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways 34927:[DB05630 DB08935] DB05630|Sodium stibogluconate TOP1 DB08935|Obinutuzumab MS4A1 common genes common pathways 34928:[DB05630 DB05131] DB05630|Sodium stibogluconate TOP1 DB05131|TTP889 F9 common genes common pathways 34929:[DB05630 DB09257] DB05630|Sodium stibogluconate TOP1 DB09257|Gimeracil DPYD common genes common pathways 34930:[DB05630 DB09546] DB05630|Sodium stibogluconate TOP1 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;TOP1 34931:[DB05630 DB08964] DB05630|Sodium stibogluconate TOP1 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways 34932:[DB05630 DB00981] DB05630|Sodium stibogluconate TOP1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0006260| DNA replication ACHE;TOP1 34933:[DB05630 DB08496] DB05630|Sodium stibogluconate TOP1 DB08496|(R)-warfarin CYP2C8;CYP2C9;CYP2C18;CYP2C19;CYP1A2;CYP1A1;CYP3A4;ALB common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;CYP1A1 34934:[DB05630 DB08879] DB05630|Sodium stibogluconate TOP1 DB08879|Belimumab TNFSF13B common genes common pathways 34935:[DB05630 DB02134] DB05630|Sodium stibogluconate TOP1 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34936:[DB05630 DB05804] DB05630|Sodium stibogluconate TOP1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 34937:[DB05630 DB00970] DB05630|Sodium stibogluconate TOP1 DB00970|Dactinomycin TOP2A;TOP2B;SLC22A5;ABCB1;ABCC6;ABCC1;ABCG2 common genes common pathways GO:0007059| chromosome segregation TOP2A;TOP1 GO:0042493| response to drug ABCB1;ABCC1;ABCG2;ABCC6;TOP1 GO:0016925| protein sumoylation TOP2B;TOP2A;TOP1 GO:0048511| rhythmic process TOP1;TOP2A GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0006265| DNA topological change TOP2B;TOP2A;TOP1 34938:[DB05630 DB13074] DB05630|Sodium stibogluconate TOP1 DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways 34939:[DB05630 DB11133] DB05630|Sodium stibogluconate TOP1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0007623| circadian rhythm TOP1;SREBF1 GO:0042493| response to drug TOP1;SREBF1;PTGS2;PPARG GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0048511| rhythmic process PPARG;PPARA;TOP1 34940:[DB05630 DB01325] DB05630|Sodium stibogluconate TOP1 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways 34941:[DB05630 DB01353] DB05630|Sodium stibogluconate TOP1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 34942:[DB05630 DB00230] DB05630|Sodium stibogluconate TOP1 DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways 34943:[DB05630 DB01162] DB05630|Sodium stibogluconate TOP1 DB01162|Terazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A;ABCB1 34944:[DB05630 DB00395] DB05630|Sodium stibogluconate TOP1 DB00395|Carisoprodol GABRA1;GABRB2;GABRG2;CYP2C19 common genes common pathways 34945:[DB05630 DB12301] DB05630|Sodium stibogluconate TOP1 DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways 34946:[DB05630 DB00758] DB05630|Sodium stibogluconate TOP1 DB00758|Clopidogrel P2RY12;CYP3A4;CYP2B6;CYP3A5;CYP2C19;CYP2C9;CYP1A2;CYP2C8;CES1;ABCB1;SLC22A1;SLC22A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;TOP1 34947:[DB05630 DB13174] DB05630|Sodium stibogluconate TOP1 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;TOP1 34948:[DB05630 DB05099] DB05630|Sodium stibogluconate TOP1 DB05099|Ancrod FGA common genes common pathways 34949:[DB05630 DB11359] DB05630|Sodium stibogluconate TOP1 DB11359|Guaiacol ALB common genes common pathways 34950:[DB05630 DB11738] DB05630|Sodium stibogluconate TOP1 DB11738|Rilmenidine ADRA2A common genes common pathways 34951:[DB05630 DB05879] DB05630|Sodium stibogluconate TOP1 DB05879|AME-527 TNF common genes common pathways 34952:[DB05630 DB00588] DB05630|Sodium stibogluconate TOP1 DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug TOP1;ABCB1 34953:[DB05630 DB08828] DB05630|Sodium stibogluconate TOP1 DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;TOP1;ABCG2 34954:[DB05630 DB07449] DB05630|Sodium stibogluconate TOP1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways GO:0006338| chromatin remodeling PADI4;TOP1 34955:[DB05630 DB00388] DB05630|Sodium stibogluconate TOP1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ADRA1A;TOP1 34956:[DB05630 DB00819] DB05630|Sodium stibogluconate TOP1 DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways GO:0042493| response to drug TOP1;AQP1 34957:[DB05630 DB00284] DB05630|Sodium stibogluconate TOP1 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 34958:[DB05630 DB01067] DB05630|Sodium stibogluconate TOP1 DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0042493| response to drug PPARG;TOP1;UGT1A1;ABCC8 GO:0048511| rhythmic process PPARG;TOP1 34959:[DB05630 DB01401] DB05630|Sodium stibogluconate TOP1 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 34960:[DB05630 DB01159] DB05630|Sodium stibogluconate TOP1 DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0042493| response to drug CYP2E1;TOP1;MT-ND1;GABRG3;GRIN2A;KCNK3 34961:[DB05630 DB09085] DB05630|Sodium stibogluconate TOP1 DB09085|Tetracaine RYR1;RYR2 common genes common pathways 34962:[DB05630 DB05889] DB05630|Sodium stibogluconate TOP1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34963:[DB05630 DB00719] DB05630|Sodium stibogluconate TOP1 DB00719|Azatadine HRH1;CYP3A4 common genes common pathways 34964:[DB05630 DB01013] DB05630|Sodium stibogluconate TOP1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug TOP1;CYP1A1 34965:[DB05630 DB04868] DB05630|Sodium stibogluconate TOP1 DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0016310| phosphorylation KIT;TOP1;ABL1 GO:0042493| response to drug TOP1;ABCG2;UGT1A1;ABCB1 34966:[DB05630 DB06235] DB05630|Sodium stibogluconate TOP1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 34967:[DB05630 DB04971] DB05630|Sodium stibogluconate TOP1 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0048511| rhythmic process TOP1;PPARG;PPARA GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0042493| response to drug PPARG;TOP1 34968:[DB05630 DB14066] DB05630|Sodium stibogluconate TOP1 DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 34969:[DB05630 DB00703] DB05630|Sodium stibogluconate TOP1 DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1 34970:[DB05630 DB00337] DB05630|Sodium stibogluconate TOP1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0018105| peptidyl-serine phosphorylation MTOR;TOP1 GO:0016310| phosphorylation TOP1;MTOR 34971:[DB05630 DB01069] DB05630|Sodium stibogluconate TOP1 DB01069|Promethazine HRH1;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;HTR2A;CALM1;HRH2;CYP2D6;CYP2B6;CYP2C9;ABCB1 common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug ABCB1;HTR2A;TOP1;DRD2;ADRA1A GO:0016032| viral reproduction TOP1;HTR2A 34972:[DB05630 DB00203] DB05630|Sodium stibogluconate TOP1 DB00203|Sildenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2D6;CYP1A1;CYP2E1;ABCC4;ABCC5;ABCC10;SLCO1B1;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1;CYP2E1;ABCB1;ABCC4 34973:[DB05630 DB06470] DB05630|Sodium stibogluconate TOP1 DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways 34974:[DB05630 DB01340] DB05630|Sodium stibogluconate TOP1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 34975:[DB05630 DB01042] DB05630|Sodium stibogluconate TOP1 DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways 34976:[DB05630 DB05297] DB05630|Sodium stibogluconate TOP1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;BCL2 GO:0042493| response to drug BCL2;TOP1 34977:[DB05630 DB00009] DB05630|Sodium stibogluconate TOP1 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm SERPINE1;TOP1 34978:[DB05630 DB08890] DB05630|Sodium stibogluconate TOP1 DB08890|Linaclotide GUCY2C common genes common pathways 34979:[DB05630 DB07285] DB05630|Sodium stibogluconate TOP1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 34980:[DB05630 DB01628] DB05630|Sodium stibogluconate TOP1 DB01628|Etoricoxib PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1;PTGS2;CYP1A2 34981:[DB05630 DB01001] DB05630|Sodium stibogluconate TOP1 DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways 34982:[DB05630 DB01002] DB05630|Sodium stibogluconate TOP1 DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 34983:[DB05630 DB04842] DB05630|Sodium stibogluconate TOP1 DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0042493| response to drug DRD2;TOP1;HTR2A GO:0032922| circadian regulation of gene expression DRD2;TOP1 34984:[DB05630 DB00509] DB05630|Sodium stibogluconate TOP1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways 34985:[DB05630 DB01392] DB05630|Sodium stibogluconate TOP1 DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction TOP1;HTR2A GO:0042493| response to drug HTR2B;KCNJ11;DRD2;HTR2A;TOP1;DRD3;HTR1B;HTR2C GO:0032922| circadian regulation of gene expression DRD3;TOP1;DRD2 34986:[DB05630 DB01809] DB05630|Sodium stibogluconate TOP1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0042493| response to drug TOP1;RET GO:0016032| viral reproduction HCK;TOP1 GO:0016310| phosphorylation RET;HCK;TOP1 34987:[DB05630 DB00833] DB05630|Sodium stibogluconate TOP1 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways 34988:[DB05630 DB00591] DB05630|Sodium stibogluconate TOP1 DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0042493| response to drug ANXA1;TOP1 GO:0007059| chromosome segregation NR3C1;TOP1 34989:[DB05630 DB01549] DB05630|Sodium stibogluconate TOP1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug TOP1;DRD2 34990:[DB05630 DB06788] DB05630|Sodium stibogluconate TOP1 DB06788|Histrelin GNRHR common genes common pathways 34991:[DB05630 DB01142] DB05630|Sodium stibogluconate TOP1 DB01142|Doxepin HRH1;HRH2;SLC6A2;SLC6A4;HTR2A;HTR2B;HTR2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR1A;ADRA2A;ADRA2B;ADRA2C;DRD2;HTR6;HRH4;KCNH2;CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;ORM1;ABCB1 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug HTR2C;CYP1A2;ABCB1;SLC6A4;DRD2;ADRA1A;TOP1;HTR2A;HTR2B;SLC6A2 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0016310| phosphorylation TOP1;HTR2B GO:0016032| viral reproduction TOP1;HTR2A 34992:[DB05630 DB05271] DB05630|Sodium stibogluconate TOP1 DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0048511| rhythmic process TOP1;DRD4 GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 GO:0042493| response to drug DRD3;TOP1;DRD1;DRD2 34993:[DB05630 DB00904] DB05630|Sodium stibogluconate TOP1 DB00904|Ondansetron HTR3A;HTR4;OPRM1;HTR1A;HTR1B;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP2C9;CYP2E1 common genes common pathways GO:0042493| response to drug HTR1B;CYP1A2;TOP1;CYP2E1 34994:[DB05630 DB12483] DB05630|Sodium stibogluconate TOP1 DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways GO:0016310| phosphorylation TOP1;PIK3CA;PIK3CD GO:0042493| response to drug ABCG2;TOP1;ABCB1 34995:[DB05630 DB11693] DB05630|Sodium stibogluconate TOP1 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 34996:[DB05630 DB06834] DB05630|Sodium stibogluconate TOP1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways GO:0018105| peptidyl-serine phosphorylation SYK;TOP1 GO:0016032| viral reproduction SYK;TOP1 GO:0016310| phosphorylation SYK;TOP1 34997:[DB05630 DB06612] DB05630|Sodium stibogluconate TOP1 DB06612|Mepolizumab IL5 common genes common pathways 34998:[DB05630 DB05152] DB05630|Sodium stibogluconate TOP1 DB05152|NGX267 CHRM1 common genes common pathways 34999:[DB05630 DB11529] DB05630|Sodium stibogluconate TOP1 DB11529|Melengestrol CYP3A4 common genes common pathways 35000:[DB05630 DB01931] DB05630|Sodium stibogluconate TOP1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways 35001:[DB05630 DB02659] DB05630|Sodium stibogluconate TOP1 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC1;TOP1;FECH;ABCB1;ABCC2;ABCC4 GO:0016032| viral reproduction SLC10A1;TOP1 35002:[DB05630 DB01189] DB05630|Sodium stibogluconate TOP1 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes common pathways GO:0042493| response to drug GABRG3;MT-ND1;TOP1 35003:[DB05630 DB05110] DB05630|Sodium stibogluconate TOP1 DB05110|VIR201 IFNG common genes common pathways 35004:[DB05630 DB00432] DB05630|Sodium stibogluconate TOP1 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways GO:0007623| circadian rhythm TOP1;TYMS GO:0042493| response to drug TYMS;TOP1 GO:0016310| phosphorylation TK1;TOP1 35005:[DB05630 DB12116] DB05630|Sodium stibogluconate TOP1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0032922| circadian regulation of gene expression AHR;TOP1 GO:0048511| rhythmic process AHR;TOP1 35006:[DB05630 DB00307] DB05630|Sodium stibogluconate TOP1 DB00307|Bexarotene RXRA;RXRB;RXRG;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0016032| viral reproduction TOP1;RXRA 35007:[DB05630 DB02309] DB05630|Sodium stibogluconate TOP1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 35008:[DB05630 DB06429] DB05630|Sodium stibogluconate TOP1 DB06429|Talnetant TACR3 common genes common pathways 35009:[DB05630 DB00731] DB05630|Sodium stibogluconate TOP1 DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0048511| rhythmic process PPARG;TOP1 GO:0042493| response to drug ABCC8;TOP1;PPARG;ABCC4 35010:[DB05630 DB04932] DB05630|Sodium stibogluconate TOP1 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0042493| response to drug ADORA2A;TOP1 35011:[DB05630 DB00334] DB05630|Sodium stibogluconate TOP1 DB00334|Olanzapine HTR2A;DRD2;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR5A;DRD1;DRD5;HRH2;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;ADRB1;ADRB2;ADRB3;CYP1A2;CYP2D6;FMO3;CYP2C19;CYP3A4;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0007623| circadian rhythm TOP1;HTR7 GO:0042493| response to drug DRD2;ADRA1A;HTR2A;TOP1;DRD1;UGT1A1;HTR2B;HTR2C;CYP1A2;DRD3;ABCB1;HTR1B;GABRG3 GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 GO:0048511| rhythmic process TOP1;DRD4 GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation HTR2B;TOP1 35012:[DB05630 DB00783] DB05630|Sodium stibogluconate TOP1 DB00783|Estradiol ESR1;ESR2;NR1I2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP3A4;CYP1A2;CYP3A5;CYP3A7;UGT1A1;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0007623| circadian rhythm NCOA2;TOP1 GO:0042493| response to drug ABCB1;CYP1A2;ABCG2;UGT1A1;BECN1;CYP1A1;TOP1 GO:0032922| circadian regulation of gene expression TOP1;NCOA2 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process NCOA2;TOP1 GO:0016032| viral reproduction TOP1;BECN1 35013:[DB05630 DB14543] DB05630|Sodium stibogluconate TOP1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0042493| response to drug ABCG2;TOP1;ABCB1;ANXA1;HSD11B2 GO:0007059| chromosome segregation NR3C1;TOP1 35014:[DB05630 DB01221] DB05630|Sodium stibogluconate TOP1 DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0016310| phosphorylation HTR2B;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug HTR1B;HTR2C;BCHE;HTR2B;SLC6A2;DRD2;HTR2A;TOP1 35015:[DB05630 DB07641] DB05630|Sodium stibogluconate TOP1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways 35016:[DB05630 DB04235] DB05630|Sodium stibogluconate TOP1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0042493| response to drug ABAT;TOP1 35017:[DB05630 DB05541] DB05630|Sodium stibogluconate TOP1 DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;SCN11A 35018:[DB05630 DB00389] DB05630|Sodium stibogluconate TOP1 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways 35019:[DB05630 DB01164] DB05630|Sodium stibogluconate TOP1 DB01164|Calcium Chloride S100A13 common genes common pathways 35020:[DB05630 DB06678] DB05630|Sodium stibogluconate TOP1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0016310| phosphorylation TOP1;HTR2B GO:0016032| viral reproduction HTR2A;TOP1 GO:0042493| response to drug TOP1;HTR2A;HTR2B;HTR2C 35021:[DB05630 DB09283] DB05630|Sodium stibogluconate TOP1 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0042493| response to drug TOP1;PDE3A 35022:[DB05630 DB00740] DB05630|Sodium stibogluconate TOP1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;TOP1;CYP1A1;CYP1A2 35023:[DB05630 DB09317] DB05630|Sodium stibogluconate TOP1 DB09317|Synthetic Conjugated Estrogens, A ESR1;CYP3A4 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 35024:[DB05630 DB01482] DB05630|Sodium stibogluconate TOP1 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35025:[DB05630 DB11772] DB05630|Sodium stibogluconate TOP1 DB11772|Pilaralisib PIK3CA common genes common pathways GO:0016310| phosphorylation TOP1;PIK3CA 35026:[DB05630 DB14067] DB05630|Sodium stibogluconate TOP1 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35027:[DB05630 DB00297] DB05630|Sodium stibogluconate TOP1 DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways 35028:[DB05630 DB11994] DB05630|Sodium stibogluconate TOP1 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;TOP1 35029:[DB05630 DB04841] DB05630|Sodium stibogluconate TOP1 DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP1A1;CYP1A2 35030:[DB05630 DB05903] DB05630|Sodium stibogluconate TOP1 DB05903|KOS-1584 CYP3A4 common genes common pathways 35031:[DB05630 DB00491] DB05630|Sodium stibogluconate TOP1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 35032:[DB05630 DB09008] DB05630|Sodium stibogluconate TOP1 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways 35033:[DB05630 DB00853] DB05630|Sodium stibogluconate TOP1 DB00853|Temozolomide CYP3A4 common genes common pathways 35034:[DB05630 DB04970] DB05630|Sodium stibogluconate TOP1 DB04970|Lesopitron HTR1A common genes common pathways 35035:[DB05630 DB00335] DB05630|Sodium stibogluconate TOP1 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 35036:[DB05630 DB14068] DB05630|Sodium stibogluconate TOP1 DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35037:[DB05630 DB01285] DB05630|Sodium stibogluconate TOP1 DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CRH 35038:[DB05630 DB08896] DB05630|Sodium stibogluconate TOP1 DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0016310| phosphorylation FLT1;RAF1;TOP1;RET;PDGFRA;FGFR1;KIT;FLT4;KDR;DDR2;MAPK11;EPHA2;NTRK1;TEK;ABL1;FRK;FGFR2;PDGFRB;BRAF GO:0016032| viral reproduction TOP1;PDGFRA;KDR;EPHA2 GO:0007623| circadian rhythm TOP1;NTRK1 GO:0042493| response to drug NTRK1;ABCB1;TOP1;RET;UGT1A1;ABCG2 35039:[DB05630 DB00015] DB05630|Sodium stibogluconate TOP1 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0007623| circadian rhythm TOP1;SERPINE1 35040:[DB05630 DB00752] DB05630|Sodium stibogluconate TOP1 DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways GO:0042493| response to drug MAOB;CYP2E1;TOP1;CYP1A2 35041:[DB05630 DB09013] DB05630|Sodium stibogluconate TOP1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways 35042:[DB05630 DB00277] DB05630|Sodium stibogluconate TOP1 DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0006338| chromatin remodeling TOP1;HDAC2 GO:0048511| rhythmic process HDAC2;TOP1 GO:0032922| circadian regulation of gene expression HDAC2;TOP1 GO:0042493| response to drug ADORA2A;HDAC2;CYP1A1;PDE3A;CYP2E1;TOP1;ADA;CYP1A2 35043:[DB05630 DB09302] DB05630|Sodium stibogluconate TOP1 DB09302|Alirocumab PCSK9 common genes common pathways 35044:[DB05630 DB13044] DB05630|Sodium stibogluconate TOP1 DB13044|Gossypol BCL2L1 common genes common pathways 35045:[DB05630 DB12789] DB05630|Sodium stibogluconate TOP1 DB12789|Dinoprost PTGDR2 common genes common pathways 35046:[DB05630 DB01244] DB05630|Sodium stibogluconate TOP1 DB01244|Bepridil CACNA1A;CACNA1H;CACNA2D2;ATP1A1;KCNQ1;TNNC1;CALM1;PDE1B;PDE1A;KCNH2;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1;ABCB1 35047:[DB05630 DB01175] DB05630|Sodium stibogluconate TOP1 DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0042493| response to drug SLC6A2;TOP1;ADRA1A;SLC6A3;SLC6A4 35048:[DB05630 DB00295] DB05630|Sodium stibogluconate TOP1 DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;TOP1 35049:[DB05630 DB01393] DB05630|Sodium stibogluconate TOP1 DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0048511| rhythmic process PPARG;PPARA;TOP1 GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0042493| response to drug PPARG;CYP1A1;TOP1 GO:0016032| viral reproduction TOP1;RXRA 35050:[DB05630 DB00894] DB05630|Sodium stibogluconate TOP1 DB00894|Testolactone CYP19A1 common genes common pathways 35051:[DB05630 DB00447] DB05630|Sodium stibogluconate TOP1 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways 35052:[DB05630 DB00492] DB05630|Sodium stibogluconate TOP1 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways 35053:[DB05630 DB00986] DB05630|Sodium stibogluconate TOP1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways 35054:[DB05630 DB05443] DB05630|Sodium stibogluconate TOP1 DB05443|ADL 10-0101 OPRK1 common genes common pathways 35055:[DB05630 DB05098] DB05630|Sodium stibogluconate TOP1 DB05098|Leptin LEPR common genes common pathways 35056:[DB05630 DB00563] DB05630|Sodium stibogluconate TOP1 DB00563|Methotrexate DHFR;DHFR;AOX1;MTHFR;PGD;FPGS;TYMS;ATIC;GGH;CYP3A4;ALB;ABCC3;ABCC4;ABCC1;SLC22A6;ABCC10;SLC22A8;ABCC2;ABCB1;SLCO1A2;SLC16A1;ABCC11;SLCO1B3;SLC22A11;SLCO1C1;SLCO3A1;ABCG2;SLC22A7;SLC46A1;SLCO1B1;SLCO4C1;SLC19A1;FOLR1 common genes common pathways GO:0042493| response to drug ABCC4;MTHFR;ABCB1;ABCC2;TOP1;GGH;TYMS;ABCG2;ABCC1 GO:0007623| circadian rhythm TYMS;TOP1 35057:[DB05630 DB00217] DB05630|Sodium stibogluconate TOP1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways 35058:[DB05630 DB09101] DB05630|Sodium stibogluconate TOP1 DB09101|Elvitegravir pol;CYP3A4 common genes common pathways 35059:[DB05630 DB09344] DB05630|Sodium stibogluconate TOP1 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways GO:0016310| phosphorylation GCK;TOP1 35060:[DB05630 DB01090] DB05630|Sodium stibogluconate TOP1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 35061:[DB05630 DB00361] DB05630|Sodium stibogluconate TOP1 DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 35062:[DB05630 DB12140] DB05630|Sodium stibogluconate TOP1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways 35063:[DB05630 DB01291] DB05630|Sodium stibogluconate TOP1 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways 35064:[DB05630 DB09262] DB05630|Sodium stibogluconate TOP1 DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways 35065:[DB05630 DB01088] DB05630|Sodium stibogluconate TOP1 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways 35066:[DB05630 DB05294] DB05630|Sodium stibogluconate TOP1 DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes common pathways GO:0007623| circadian rhythm EGFR;TOP1 GO:0042493| response to drug TOP1;RET;ABCC1;ABCG2 GO:0016310| phosphorylation EGFR;TOP1;RET;PTK6;TEK 35067:[DB05630 DB04845] DB05630|Sodium stibogluconate TOP1 DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways 35068:[DB05630 DB02852] DB05630|Sodium stibogluconate TOP1 DB02852|Domoic Acid GRIK2 common genes common pathways 35069:[DB05630 DB06413] DB05630|Sodium stibogluconate TOP1 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0042493| response to drug CYP1A2;SLC6A3;TOP1 35070:[DB05630 DB00544] DB05630|Sodium stibogluconate TOP1 DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0007623| circadian rhythm TOP1;TYMS GO:0042493| response to drug ABCC4;MTHFR;CYP1A2;ABCG2;PPAT;TOP1;TYMS 35071:[DB05630 DB00542] DB05630|Sodium stibogluconate TOP1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug TOP1;MTHFR 35072:[DB05630 DB00742] DB05630|Sodium stibogluconate TOP1 DB00742|Mannitol ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35073:[DB05630 DB12391] DB05630|Sodium stibogluconate TOP1 DB12391|Sagopilone CYP3A4 common genes common pathways 35074:[DB05630 DB13261] DB05630|Sodium stibogluconate TOP1 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35075:[DB05630 DB01093] DB05630|Sodium stibogluconate TOP1 DB01093|Dimethyl sulfoxide CYP2C19;CYP2D6;CYP3A4;TTR common genes common pathways 35076:[DB05630 DB06116] DB05630|Sodium stibogluconate TOP1 DB06116|Eldelumab CXCL10 common genes common pathways 35077:[DB05630 DB08870] DB05630|Sodium stibogluconate TOP1 DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways 35078:[DB05630 DB01785] DB05630|Sodium stibogluconate TOP1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0016032| viral reproduction TOP1;FDPS 35079:[DB05630 DB03683] DB05630|Sodium stibogluconate TOP1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 35080:[DB05630 DB01413] DB05630|Sodium stibogluconate TOP1 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 35081:[DB05630 DB09212] DB05630|Sodium stibogluconate TOP1 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 35082:[DB05630 DB06089] DB05630|Sodium stibogluconate TOP1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways 35083:[DB05630 DB00012] DB05630|Sodium stibogluconate TOP1 DB00012|Darbepoetin alfa EPOR common genes common pathways 35084:[DB05630 DB09119] DB05630|Sodium stibogluconate TOP1 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug UGT1A1;TOP1 35085:[DB05630 DB03929] DB05630|Sodium stibogluconate TOP1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways 35086:[DB05630 DB00201] DB05630|Sodium stibogluconate TOP1 DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes common pathways GO:0016310| phosphorylation PIK3CD;PRKDC;PIK3CA;TOP1;ATM;PIK3CB GO:0040016| embryonic cleavage TOP1;PIK3CB GO:0006260| DNA replication ATM;TOP1 GO:0018105| peptidyl-serine phosphorylation ATM;TOP1;PRKDC GO:0048511| rhythmic process PRKDC;TOP1 GO:0042493| response to drug CYP2E1;TOP1;CYP1A1;PDE3A;ADORA2A;CYP1A2;ABCB1 35087:[DB05630 DB00972] DB05630|Sodium stibogluconate TOP1 DB00972|Azelastine HRH1;CYP1A2;CYP3A4;CYP2C19;CYP1A1;CYP3A5;CYP2C9;CYP2C8;CYP2D6;CYP2A6;CYP2B6;CYP2E1;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1;CYP2E1;CYP1A2;ABCB1 35088:[DB05630 DB12455] DB05630|Sodium stibogluconate TOP1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35089:[DB05630 DB00774] DB05630|Sodium stibogluconate TOP1 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:0042493| response to drug CA9;ATP1A1;TOP1 35090:[DB05630 DB00402] DB05630|Sodium stibogluconate TOP1 DB00402|Eszopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0042493| response to drug TOP1;TSPO;GABRG3 35091:[DB05630 DB01567] DB05630|Sodium stibogluconate TOP1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 35092:[DB05630 DB00480] DB05630|Sodium stibogluconate TOP1 DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways GO:0042493| response to drug PTGS2;TOP1;ABCB1 35093:[DB05630 DB00771] DB05630|Sodium stibogluconate TOP1 DB00771|Clidinium CHRM1 common genes common pathways 35094:[DB05630 DB00700] DB05630|Sodium stibogluconate TOP1 DB00700|Eplerenone NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP11B2 common genes common pathways 35095:[DB05630 DB00107] DB05630|Sodium stibogluconate TOP1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0042493| response to drug TOP1;OXTR 35096:[DB05630 DB09214] DB05630|Sodium stibogluconate TOP1 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 35097:[DB05630 DB00659] DB05630|Sodium stibogluconate TOP1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0042493| response to drug TOP1;GRIN2A;GABRG3 35098:[DB05630 DB01609] DB05630|Sodium stibogluconate TOP1 DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1;UGT1A1 35099:[DB05630 DB09043] DB05630|Sodium stibogluconate TOP1 DB09043|Albiglutide GLP1R common genes common pathways 35100:[DB05630 DB00412] DB05630|Sodium stibogluconate TOP1 DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0016032| viral reproduction TOP1;RXRA GO:0048511| rhythmic process TOP1;PPARA;PPARG GO:0032922| circadian regulation of gene expression PPARA;TOP1 GO:0042493| response to drug PPARG;CYP1A2;TOP1 35101:[DB05630 DB01608] DB05630|Sodium stibogluconate TOP1 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0042493| response to drug DRD1;TOP1 35102:[DB05630 DB06719] DB05630|Sodium stibogluconate TOP1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways 35103:[DB05630 DB14487] DB05630|Sodium stibogluconate TOP1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0016032| viral reproduction CFH;MDM2;APOA2;IDE;SIVA1;TP73;HDAC1;TP53;TOP1 GO:0016310| phosphorylation TOP1;NME1 GO:0032922| circadian regulation of gene expression HDAC1;TOP1 GO:0016925| protein sumoylation TOP1;MDM2 GO:0042493| response to drug HDAC4;APOA2;MDM2;MGMT;TP73;HDAC1;TP53;SOD1;TOP1;APOA1;NME1 GO:0006338| chromatin remodeling HDAC4;ESR1;HDAC1;TOP1 GO:0012501| programmed cell death TP53;TOP1 GO:0048511| rhythmic process HDAC1;TP53;TOP1 35104:[DB05630 DB01119] DB05630|Sodium stibogluconate TOP1 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0042493| response to drug KCNJ11;ATP1A1;TOP1 35105:[DB05630 DB00026] DB05630|Sodium stibogluconate TOP1 DB00026|Anakinra IL1R1 common genes common pathways 35106:[DB05630 DB04908] DB05630|Sodium stibogluconate TOP1 DB04908|Flibanserin HTR1A;HTR2A;DRD4;CYP3A4 common genes common pathways GO:0048511| rhythmic process DRD4;TOP1 GO:0042493| response to drug TOP1;HTR2A GO:0016032| viral reproduction TOP1;HTR2A 35107:[DB05630 DB00842] DB05630|Sodium stibogluconate TOP1 DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 35108:[DB05630 DB04552] DB05630|Sodium stibogluconate TOP1 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 35109:[DB05630 DB05992] DB05630|Sodium stibogluconate TOP1 DB05992|Plinabulin TNF common genes common pathways 35110:[DB05630 DB00440] DB05630|Sodium stibogluconate TOP1 DB00440|Trimethoprim TYMS;DHFR;CYP3A4;CYP2C8;CYP2C9;ABCB1;SLC22A2 common genes common pathways GO:0007623| circadian rhythm TOP1;TYMS GO:0042493| response to drug TYMS;TOP1;ABCB1 35111:[DB05630 DB00184] DB05630|Sodium stibogluconate TOP1 DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0042493| response to drug CYP1A2;CYP1A1;MAOB;CYP2E1;TOP1 35112:[DB05630 DB06777] DB05630|Sodium stibogluconate TOP1 DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways 35113:[DB05630 DB08479] DB05630|Sodium stibogluconate TOP1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0007623| circadian rhythm TOP1;TYMS GO:0042493| response to drug TYMS;TOP1 35114:[DB05630 DB04630] DB05630|Sodium stibogluconate TOP1 DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug TOP1;ABCB1 35115:[DB05630 DB00482] DB05630|Sodium stibogluconate TOP1 DB00482|Celecoxib PTGS2;PDPK1;CA2;CA3;ABCB5;ABCG2;ABCB1;CYP3A4;CYP2C9;CYP2D6;CYP2C8;ABCC4;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;PTGS2;ABCC4;ABCB1 GO:0016310| phosphorylation PDPK1;TOP1 GO:0018105| peptidyl-serine phosphorylation PDPK1;TOP1 35116:[DB05630 DB01035] DB05630|Sodium stibogluconate TOP1 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0042493| response to drug TOP1;BCHE 35117:[DB05630 DB05969] DB05630|Sodium stibogluconate TOP1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0016310| phosphorylation TOP1;CDK7 35118:[DB05630 DB00809] DB05630|Sodium stibogluconate TOP1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways 35119:[DB05630 DB00648] DB05630|Sodium stibogluconate TOP1 DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 35120:[DB05630 DB02303] DB05630|Sodium stibogluconate TOP1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways 35121:[DB05630 DB00004] DB05630|Sodium stibogluconate TOP1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0016032| viral reproduction IL2RG;IL2RB;TOP1 35122:[DB05630 DB05461] DB05630|Sodium stibogluconate TOP1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug TOP1;HTR2B GO:0016310| phosphorylation TOP1;HTR2B 35123:[DB05630 DB01238] DB05630|Sodium stibogluconate TOP1 DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0048511| rhythmic process TOP1;DRD4 GO:0007623| circadian rhythm HTR7;TOP1 GO:0032922| circadian regulation of gene expression DRD3;TOP1;DRD2 GO:0042493| response to drug DRD2;ADRA1A;DRD1;TOP1;HTR2A;HTR2C;HTR1B;DRD3 GO:0016032| viral reproduction HTR2A;TOP1 35124:[DB05630 DB02901] DB05630|Sodium stibogluconate TOP1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0006338| chromatin remodeling TOP1;ESR1 35125:[DB05630 DB06710] DB05630|Sodium stibogluconate TOP1 DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 35126:[DB05630 DB04838] DB05630|Sodium stibogluconate TOP1 DB04838|Cyclandelate CACNA2D1;CES1;CYP3A4 common genes common pathways 35127:[DB05630 DB07477] DB05630|Sodium stibogluconate TOP1 DB07477|Felbinac CTSL common genes common pathways 35128:[DB05630 DB01156] DB05630|Sodium stibogluconate TOP1 DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1;SLC6A3;SLC6A2 35129:[DB05630 DB00496] DB05630|Sodium stibogluconate TOP1 DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways 35130:[DB05630 DB04070] DB05630|Sodium stibogluconate TOP1 DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways 35131:[DB05630 DB00807] DB05630|Sodium stibogluconate TOP1 DB00807|Proparacaine SCN10A common genes common pathways 35132:[DB05630 DB00318] DB05630|Sodium stibogluconate TOP1 DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0042493| response to drug TOP1;UGT1A1 35133:[DB05630 DB00443] DB05630|Sodium stibogluconate TOP1 DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 GO:0042493| response to drug ABCB1;TOP1 35134:[DB05630 DB01972] DB05630|Sodium stibogluconate TOP1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0016310| phosphorylation GUK1;TOP1 35135:[DB05630 DB01217] DB05630|Sodium stibogluconate TOP1 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35136:[DB05630 DB07637] DB05630|Sodium stibogluconate TOP1 DB07637|Dibromotyrosine EPOR common genes common pathways 35137:[DB05630 DB06791] DB05630|Sodium stibogluconate TOP1 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways 35138:[DB05630 DB01622] DB05630|Sodium stibogluconate TOP1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0016032| viral reproduction TOP1;HTR2A GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug DRD1;TOP1;HTR2A;DRD2;ADRA1A 35139:[DB05630 DB09286] DB05630|Sodium stibogluconate TOP1 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0042493| response to drug DRD3;DRD2;ADRA1A;HTR2A;TOP1;DRD1;HTR2B GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0048511| rhythmic process DRD4;TOP1 GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation HTR2B;TOP1 35140:[DB05630 DB01062] DB05630|Sodium stibogluconate TOP1 DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways 35141:[DB05630 DB00780] DB05630|Sodium stibogluconate TOP1 DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways GO:0042493| response to drug ABAT;MAOB;TOP1;CYP2E1 35142:[DB05630 DB05767] DB05630|Sodium stibogluconate TOP1 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0048511| rhythmic process TOP1;NFKB2 35143:[DB05630 DB06820] DB05630|Sodium stibogluconate TOP1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 35144:[DB05630 DB01320] DB05630|Sodium stibogluconate TOP1 DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35145:[DB05630 DB00871] DB05630|Sodium stibogluconate TOP1 DB00871|Terbutaline ADRB2;ADRB3;ADRB1;BCHE common genes common pathways GO:0042493| response to drug TOP1;BCHE 35146:[DB05630 DB00933] DB05630|Sodium stibogluconate TOP1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug TOP1;HTR2A;DRD2 35147:[DB05630 DB00500] DB05630|Sodium stibogluconate TOP1 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 35148:[DB05630 DB00804] DB05630|Sodium stibogluconate TOP1 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;TOP1 35149:[DB05630 DB00223] DB05630|Sodium stibogluconate TOP1 DB00223|Diflorasone NR3C1 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 35150:[DB05630 DB01388] DB05630|Sodium stibogluconate TOP1 DB01388|Mibefradil CACNA1G;CACNA1H;CACNA1C;CACNA1D;CACNA1F;CACNA1I;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP1A1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;TOP1;CYP1A1 35151:[DB05630 DB00106] DB05630|Sodium stibogluconate TOP1 DB00106|Abarelix GNRHR common genes common pathways 35152:[DB05630 DB00014] DB05630|Sodium stibogluconate TOP1 DB00014|Goserelin LHCGR;GNRHR common genes common pathways 35153:[DB05630 DB01115] DB05630|Sodium stibogluconate TOP1 DB01115|Nifedipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CALM1;KCNA1;CACNA1H;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2A6;CYP2C8;CYP2D6;CYP2E1;CYP1A1;CYP2B6;ABCC3;ABCB1;ABCC2;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;CYP1A1;CYP1A2;ABCB1;ABCC2 35154:[DB05630 DB14062] DB05630|Sodium stibogluconate TOP1 DB14062|Concanamycin A ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35155:[DB05630 DB09118] DB05630|Sodium stibogluconate TOP1 DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0042493| response to drug LDHA;TOP1;GABRG3;CYP1A2 35156:[DB05630 DB14514] DB05630|Sodium stibogluconate TOP1 DB14514|Magnesium levulinate ATP1A1 common genes common pathways GO:0042493| response to drug TOP1;ATP1A1 35157:[DB05630 DB04787] DB05630|Sodium stibogluconate TOP1 DB04787|Tanaproget PGR common genes common pathways 35158:[DB05630 DB01116] DB05630|Sodium stibogluconate TOP1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0042493| response to drug TOP1;BCHE 35159:[DB05630 DB11943] DB05630|Sodium stibogluconate TOP1 DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways GO:0042493| response to drug ABCG2;UGT1A1;CYP2E1;TOP1 35160:[DB05630 DB01558] DB05630|Sodium stibogluconate TOP1 DB01558|Bromazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug TOP1;CYP2E1;CYP1A2;GABRG3 35161:[DB05630 DB08932] DB05630|Sodium stibogluconate TOP1 DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes common pathways 35162:[DB05630 DB13975] DB05630|Sodium stibogluconate TOP1 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 35163:[DB05630 DB09327] DB05630|Sodium stibogluconate TOP1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0042493| response to drug TOP1;TYMS GO:0007623| circadian rhythm TYMS;TOP1 35164:[DB05630 DB00042] DB05630|Sodium stibogluconate TOP1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 35165:[DB05630 DB00254] DB05630|Sodium stibogluconate TOP1 DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006338| chromatin remodeling TOP1;PADI4 GO:0042493| response to drug B2M;TOP1 35166:[DB05630 DB08744] DB05630|Sodium stibogluconate TOP1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways 35167:[DB05630 DB04253] DB05630|Sodium stibogluconate TOP1 DB04253|Tretazicar NQO2 common genes common pathways 35168:[DB05630 DB05246] DB05630|Sodium stibogluconate TOP1 DB05246|Methsuximide CACNA1G;CYP2C19 common genes common pathways 35169:[DB05630 DB00938] DB05630|Sodium stibogluconate TOP1 DB00938|Salmeterol ADRB2;ADRB1;ADRB3;CYP3A4;CYP3A5;CYP3A7;CYP2C8 common genes common pathways 35170:[DB05630 DB05259] DB05630|Sodium stibogluconate TOP1 DB05259|Glatiramer HLA-DRB1 common genes common pathways 35171:[DB05630 DB13955] DB05630|Sodium stibogluconate TOP1 DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0016032| viral reproduction TOP1;BECN1 GO:0007623| circadian rhythm NCOA2;TOP1 GO:0032922| circadian regulation of gene expression NCOA2;TOP1 GO:0042493| response to drug ABCG2;UGT1A1;CYP1A1;BECN1;TOP1;ABCB1;CYP1A2 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process NCOA2;TOP1 35172:[DB05630 DB00546] DB05630|Sodium stibogluconate TOP1 DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 35173:[DB05630 DB14700] DB05630|Sodium stibogluconate TOP1 DB14700|Damoctocog alfa pegol F8 common genes common pathways 35174:[DB05630 DB01158] DB05630|Sodium stibogluconate TOP1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 35175:[DB05630 DB09381] DB05630|Sodium stibogluconate TOP1 DB09381|Estrogens, esterified CYP3A4 common genes common pathways 35176:[DB05630 DB00418] DB05630|Sodium stibogluconate TOP1 DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0042493| response to drug GRIN2A;CYP1A2;TOP1 35177:[DB05630 DB09095] DB05630|Sodium stibogluconate TOP1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation NR3C1;TOP1 35178:[DB05630 DB13345] DB05630|Sodium stibogluconate TOP1 DB13345|Dihydroergocristine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD1;DRD5;DRD2;DRD3;DRD4;CYP3A4;ABCB11 common genes common pathways GO:0007623| circadian rhythm TOP1;HTR7 GO:0042493| response to drug HTR2C;DRD3;HTR1B;DRD2;ADRA1A;HTR2A;TOP1;DRD1;HTR2B GO:0032922| circadian regulation of gene expression DRD3;DRD2;TOP1 GO:0048511| rhythmic process TOP1;DRD4 GO:0016032| viral reproduction TOP1;HTR2A GO:0016310| phosphorylation HTR2B;TOP1 35179:[DB05630 DB13915] DB05630|Sodium stibogluconate TOP1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways 35180:[DB05630 DB06623] DB05630|Sodium stibogluconate TOP1 DB06623|Flupirtine ADRA2A common genes common pathways 35181:[DB05630 DB00428] DB05630|Sodium stibogluconate TOP1 DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;TOP1;CYP2E1 35182:[DB05630 DB09244] DB05630|Sodium stibogluconate TOP1 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways 35183:[DB05630 DB00387] DB05630|Sodium stibogluconate TOP1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways 35184:[DB05630 DB11718] DB05630|Sodium stibogluconate TOP1 DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0016310| phosphorylation BRAF;TOP1 GO:0042493| response to drug TOP1;CCND1 35185:[DB05630 DB05133] DB05630|Sodium stibogluconate TOP1 DB05133|VP025 IL1B common genes common pathways 35186:[DB05630 DB00956] DB05630|Sodium stibogluconate TOP1 DB00956|Hydrocodone OPRM1;OPRD1;CYP2D6;CYP3A4 common genes common pathways 35187:[DB05630 DB01235] DB05630|Sodium stibogluconate TOP1 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0048511| rhythmic process TOP1;DRD4 GO:0042493| response to drug DRD3;DRD2;TOP1;DRD1 GO:0032922| circadian regulation of gene expression DRD2;TOP1;DRD3 GO:0007623| circadian rhythm TOP1;DDC 35188:[DB05630 DB02709] DB05630|Sodium stibogluconate TOP1 DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 GO:0048511| rhythmic process TOP1;AHR;CSNK2A1;PPARA;PPARG GO:0007623| circadian rhythm MTNR1A;MTNR1B;TOP1 GO:0042493| response to drug SNCA;PTGS2;CYP1A1;TOP1;PPARG;CYP1A2 GO:0032922| circadian regulation of gene expression TOP1;AHR;PPARA GO:0016310| phosphorylation PI4K2B;CSNK2A1;TOP1;AKT1 GO:0018105| peptidyl-serine phosphorylation AKT1;TOP1 GO:0016032| viral reproduction ITGA5;TOP1;ITGB3 35189:[DB05630 DB00590] DB05630|Sodium stibogluconate TOP1 DB00590|Doxazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;CYP2C19;CYP2D6;CYP3A4;ORM1;ABCB1;SLC22A1 common genes common pathways GO:0042493| response to drug ADRA1A;TOP1;ABCB1 35190:[DB05630 DB01278] DB05630|Sodium stibogluconate TOP1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways 35191:[DB05630 DB00333] DB05630|Sodium stibogluconate TOP1 DB00333|Methadone OPRM1;GRIN3A;CHRNA10;OPRD1;HTR3A;LY96;ORM2;CYP3A4;CYP2C19;CYP3A5;CYP3A7;CYP2D6;CYP2B6;CYP2C8;CYP19A1;CYP1A2;CYP2C18;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1;CYP1A2 35192:[DB05630 DB05369] DB05630|Sodium stibogluconate TOP1 DB05369|HZT-501 HRH2 common genes common pathways 35193:[DB05630 DB01348] DB05630|Sodium stibogluconate TOP1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways 35194:[DB05630 DB00961] DB05630|Sodium stibogluconate TOP1 DB00961|Mepivacaine SCN10A common genes common pathways 35195:[DB05630 DB09054] DB05630|Sodium stibogluconate TOP1 DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;ABCB1 35196:[DB05630 DB06825] DB05630|Sodium stibogluconate TOP1 DB06825|Triptorelin GNRHR common genes common pathways 35197:[DB05630 DB01941] DB05630|Sodium stibogluconate TOP1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways 35198:[DB05630 DB01565] DB05630|Sodium stibogluconate TOP1 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways 35199:[DB05630 DB14575] DB05630|Sodium stibogluconate TOP1 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug UGT1A1;TOP1 35200:[DB05630 DB09270] DB05630|Sodium stibogluconate TOP1 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 GO:0016032| viral reproduction TOP1;LDLR 35201:[DB05630 DB12406] DB05630|Sodium stibogluconate TOP1 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35202:[DB05630 DB09199] DB05630|Sodium stibogluconate TOP1 DB09199|Netoglitazone CYP3A4;CYP2C8 common genes common pathways 35203:[DB05630 DB05675] DB05630|Sodium stibogluconate TOP1 DB05675|EP-2104R FGA common genes common pathways 35204:[DB05630 DB00327] DB05630|Sodium stibogluconate TOP1 DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways 35205:[DB05630 DB08439] DB05630|Sodium stibogluconate TOP1 DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 35206:[DB05630 DB00073] DB05630|Sodium stibogluconate TOP1 DB00073|Rituximab MS4A1 common genes common pathways 35207:[DB05630 DB06494] DB05630|Sodium stibogluconate TOP1 DB06494|Sufugolix GNRHR common genes common pathways 35208:[DB05630 DB07108] DB05630|Sodium stibogluconate TOP1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways 35209:[DB05630 DB05239] DB05630|Sodium stibogluconate TOP1 DB05239|Cobimetinib MAP2K1;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0016310| phosphorylation TOP1;MAP2K1 GO:0042493| response to drug ABCB1;ABCG2;TOP1 35210:[DB05630 DB02703] DB05630|Sodium stibogluconate TOP1 DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCG2;TOP1;ABCC2 35211:[DB05630 DB06264] DB05630|Sodium stibogluconate TOP1 DB06264|Tolperisone CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35212:[DB05630 DB00518] DB05630|Sodium stibogluconate TOP1 DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;TOP1;CYP1A1 35213:[DB05630 DB13835] DB05630|Sodium stibogluconate TOP1 DB13835|Caroverine CYP3A4 common genes common pathways 35214:[DB05630 DB01227] DB05630|Sodium stibogluconate TOP1 DB01227|Levacetylmethadol OPRM1;CHRNB4;CHRNA3;CYP3A5;CYP3A7;CYP3A4;CYP19A1 common genes common pathways 35215:[DB05630 DB01699] DB05630|Sodium stibogluconate TOP1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0042493| response to drug TOP1;ABAT 35216:[DB05630 DB00268] DB05630|Sodium stibogluconate TOP1 DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0016310| phosphorylation HTR2B;TOP1 GO:0016032| viral reproduction HTR2A;TOP1 GO:0048511| rhythmic process DRD4;TOP1 GO:0032922| circadian regulation of gene expression TOP1;DRD2;DRD3 GO:0042493| response to drug CYP1A2;HTR2C;HTR1B;DRD3;DRD1;TOP1;HTR2A;DRD2;HTR2B 35217:[DB05630 DB01196] DB05630|Sodium stibogluconate TOP1 DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0042493| response to drug ABCB1;TOP1 35218:[DB05630 DB11362] DB05630|Sodium stibogluconate TOP1 DB11362|Selexipag PTGIR;CES1;CYP2C8;CYP3A4;SLCO1B1;SLCO1B3;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35219:[DB05630 DB01039] DB05630|Sodium stibogluconate TOP1 DB01039|Fenofibrate PPARA;PPARG;PPARD;NR1I2;CYP2C8;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0042493| response to drug UGT1A1;TOP1;PPARG GO:0032922| circadian regulation of gene expression TOP1;PPARA GO:0048511| rhythmic process TOP1;PPARG;PPARA 35220:[DB05630 DB06263] DB05630|Sodium stibogluconate TOP1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0040016| embryonic cleavage TOP1;TOP2A GO:0006265| DNA topological change TOP2A;TOP1 GO:0016925| protein sumoylation TOP1;TOP2A GO:0042493| response to drug POR;TOP1 GO:0007059| chromosome segregation TOP1;TOP2A GO:0048511| rhythmic process TOP2A;TOP1 35221:[DB05630 DB00186] DB05630|Sodium stibogluconate TOP1 DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0042493| response to drug TSPO;GABRG3;TOP1 35222:[DB05630 DB05710] DB05630|Sodium stibogluconate TOP1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways 35223:[DB05630 DB00426] DB05630|Sodium stibogluconate TOP1 DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways 35224:[DB05630 DB06809] DB05630|Sodium stibogluconate TOP1 DB06809|Plerixafor CXCR4 common genes common pathways GO:0016032| viral reproduction TOP1;CXCR4 35225:[DB05630 DB09068] DB05630|Sodium stibogluconate TOP1 DB09068|Vortioxetine SLC6A4;HTR3A;HTR7;HTR1B;HTR1A;ADRB1;CYP2D6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2A6;CYP2C8;CYP2B6 common genes common pathways GO:0007623| circadian rhythm TOP1;HTR7;SLC6A4 GO:0042493| response to drug TOP1;SLC6A4;HTR1B 35226:[DB05630 DB01082] DB05630|Sodium stibogluconate TOP1 DB01082|Streptomycin rpsL;PADI4;SLC22A6 common genes common pathways GO:0006338| chromatin remodeling PADI4;TOP1 35227:[DB05630 DB00753] DB05630|Sodium stibogluconate TOP1 DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0042493| response to drug MT-ND1;GABRG3;TOP1;CYP2E1 35228:[DB05630 DB01140] DB05630|Sodium stibogluconate TOP1 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways 35229:[DB05630 DB12161] DB05630|Sodium stibogluconate TOP1 DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;TOP1 35230:[DB05630 DB05432] DB05630|Sodium stibogluconate TOP1 DB05432|DAS-431 IV CALY common genes common pathways 35231:[DB05630 DB08909] DB05630|Sodium stibogluconate TOP1 DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways 35232:[DB05630 DB13125] DB05630|Sodium stibogluconate TOP1 DB13125|Lusutrombopag MPL;CYP4A11;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug TOP1;ABCG2;ABCB1 35233:[DB05630 DB01201] DB05630|Sodium stibogluconate TOP1 DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways 35234:[DB05630 DB00688] DB05630|Sodium stibogluconate TOP1 DB00688|Mycophenolate mofetil IMPDH1;IMPDH2;UGT1A1;UGT1A7;UGT1A6;UGT1A9;UGT2B7;UGT1A8;UGT1A10;CES1;CES2;CYP3A4;CYP3A5;CYP2C8;ALB;SLCO1B1;SLCO1B3;ABCC2;ABCG2;ABCB1 common genes common pathways GO:0007623| circadian rhythm IMPDH2;TOP1 GO:0042493| response to drug TOP1;ABCG2;UGT1A1;ABCB1;ABCC2 35235:[DB05630 DB04901] DB05630|Sodium stibogluconate TOP1 DB04901|Galiximab CD80 common genes common pathways GO:0016032| viral reproduction TOP1;CD80 35236:[DB05630 DB06393] DB05630|Sodium stibogluconate TOP1 DB06393|Xaliproden HTR1A common genes common pathways 35237:[DB05630 DB00747] DB05630|Sodium stibogluconate TOP1 DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35238:[DB05630 DB01117] DB05630|Sodium stibogluconate TOP1 DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways GO:0042493| response to drug TOP1;DHODH;MT-CYB 35239:[DB05630 DB04855] DB05630|Sodium stibogluconate TOP1 DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ADRA1A;ABCB1 35240:[DB05630 DB13909] DB05630|Sodium stibogluconate TOP1 DB13909|Bismuth subgallate ALB common genes common pathways 35241:[DB05630 DB00343] DB05630|Sodium stibogluconate TOP1 DB00343|Diltiazem CACNG1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2D6;CYP2C8;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 35242:[DB05630 DB04065] DB05630|Sodium stibogluconate TOP1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways 35243:[DB05630 DB00844] DB05630|Sodium stibogluconate TOP1 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways 35244:[DB05630 DB00624] DB05630|Sodium stibogluconate TOP1 DB00624|Testosterone AR;ESR1;NR3C2;CYP3A5;CYP19A1;CYP11A1;MAOA;CYP3A7;CYP3A4;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes common pathways GO:0016032| viral reproduction TOP1;SLC10A1 GO:0006338| chromatin remodeling ESR1;TOP1 GO:0042493| response to drug ABCG2;CYP1A1;TOP1;ABCB1 35245:[DB05630 DB01112] DB05630|Sodium stibogluconate TOP1 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways 35246:[DB05630 DB00934] DB05630|Sodium stibogluconate TOP1 DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0007623| circadian rhythm TOP1;HTR7 GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0042493| response to drug DRD2;ADRA1A;TOP1;HTR2A;SLC6A2;HTR2C;CYP1A2 GO:0016032| viral reproduction HTR2A;TOP1 35247:[DB05630 DB11386] DB05630|Sodium stibogluconate TOP1 DB11386|Chlorobutanol KCNH2 common genes common pathways 35248:[DB05630 DB13951] DB05630|Sodium stibogluconate TOP1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0006338| chromatin remodeling TOP1;ESR1 35249:[DB05630 DB14003] DB05630|Sodium stibogluconate TOP1 DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0016032| viral reproduction SCARB1;TOP1;LDLR 35250:[DB05630 DB09128] DB05630|Sodium stibogluconate TOP1 DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug DRD2;TOP1;HTR2A GO:0032922| circadian regulation of gene expression DRD2;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 35251:[DB05630 DB09202] DB05630|Sodium stibogluconate TOP1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug TOP1;ADRA1A 35252:[DB05630 DB11642] DB05630|Sodium stibogluconate TOP1 DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35253:[DB05630 DB07177] DB05630|Sodium stibogluconate TOP1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 35254:[DB05630 DB03793] DB05630|Sodium stibogluconate TOP1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways 35255:[DB05630 DB02925] DB05630|Sodium stibogluconate TOP1 DB02925|Piretanide SLC12A1 common genes common pathways 35256:[DB05630 DB06273] DB05630|Sodium stibogluconate TOP1 DB06273|Tocilizumab IL6R;CYP3A4 common genes common pathways 35257:[DB05630 DB13501] DB05630|Sodium stibogluconate TOP1 DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 35258:[DB05630 DB00603] DB05630|Sodium stibogluconate TOP1 DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 35259:[DB05630 DB06480] DB05630|Sodium stibogluconate TOP1 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 35260:[DB05630 DB04216] DB05630|Sodium stibogluconate TOP1 DB04216|Quercetin HCK;PIK3CG;UGT3A1;ATP5B;PIM1;HIBCH;fabZ;STK17B;ESR1;ESR2;NQO2;AHR;CYP1B1;ACTB;CSNK2A1;CSNK2B;EIF3F;HSP90AA1;HSPA2;RUVBL2;SF3B3;UBA1;SHBG;CBR1;CEBPB;NR1I2;CYP2C8;ALB;ABCC1;ABCC2;SLC16A7;SLCO2B1;ABCB1;SLC16A1;ABCG2;SLCO1B1 common genes common pathways GO:0016032| viral reproduction TOP1;HCK GO:0016310| phosphorylation HCK;PIM1;TOP1;CSNK2A1;STK17B;PIK3CG GO:0032922| circadian regulation of gene expression AHR;TOP1 GO:0042493| response to drug TOP1;ABCC1;ABCG2;ABCB1;ABCC2 GO:0006338| chromatin remodeling TOP1;RUVBL2;ESR1 GO:0012501| programmed cell death STK17B;TOP1 GO:0048511| rhythmic process CSNK2A1;AHR;TOP1 35261:[DB05630 DB13293] DB05630|Sodium stibogluconate TOP1 DB13293|Ipecac CYP2D6;CYP3A4 common genes common pathways 35262:[DB05630 DB01616] DB05630|Sodium stibogluconate TOP1 DB01616|Alverine HTR1A common genes common pathways 35263:[DB05630 DB00472] DB05630|Sodium stibogluconate TOP1 DB00472|Fluoxetine SLC6A4;KCNH2;HTR2C;CKS1B;CHRNA2;CHRNA3;CHRNB4;CYP2C19;CYP2D6;CYP2C9;CYP2B;CYP1A2;CYP3A4;CYP2B6;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0007623| circadian rhythm TOP1;SLC6A4 GO:0042493| response to drug ABCB1;SLC6A4;HTR2C;CYP1A2;TOP1 35264:[DB05630 DB01250] DB05630|Sodium stibogluconate TOP1 DB01250|Olsalazine TPMT;IFNG common genes common pathways 35265:[DB05630 DB00881] DB05630|Sodium stibogluconate TOP1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways 35266:[DB05630 DB09117] DB05630|Sodium stibogluconate TOP1 DB09117|Paraldehyde ALDH2 common genes common pathways 35267:[DB05630 DB00170] DB05630|Sodium stibogluconate TOP1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0042493| response to drug MTHFR;CYP1A2;TOP1;CYP2E1;CYP1A1 GO:0007623| circadian rhythm TOP1;F7 35268:[DB05630 DB06403] DB05630|Sodium stibogluconate TOP1 DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 35269:[DB05630 DB08577] DB05630|Sodium stibogluconate TOP1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways GO:0016310| phosphorylation TOP1;FGFR1 35270:[DB05630 DB01333] DB05630|Sodium stibogluconate TOP1 DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways 35271:[DB05630 DB01339] DB05630|Sodium stibogluconate TOP1 DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways GO:0042493| response to drug TOP1;ABCB1 35272:[DB05630 DB00065] DB05630|Sodium stibogluconate TOP1 DB00065|Infliximab TNF common genes common pathways 35273:[DB05630 DB13857] DB05630|Sodium stibogluconate TOP1 DB13857|Demegestone PGR;CYP3A4 common genes common pathways 35274:[DB05630 DB05939] DB05630|Sodium stibogluconate TOP1 DB05939|MK-0354 GPER1 common genes common pathways 35275:[DB05630 DB06168] DB05630|Sodium stibogluconate TOP1 DB06168|Canakinumab IL1B common genes common pathways 35276:[DB05630 DB00272] DB05630|Sodium stibogluconate TOP1 DB00272|Betazole HRH2 common genes common pathways 35277:[DB05630 DB00952] DB05630|Sodium stibogluconate TOP1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0042493| response to drug HTR1B;TOP1 35278:[DB05630 DB11328] DB05630|Sodium stibogluconate TOP1 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways 35279:[DB05630 DB00909] DB05630|Sodium stibogluconate TOP1 DB00909|Zonisamide SCN1A;SCN2A;SCN3A;SCN4A;SCN5A;SCN9A;SCN11A;SCN1B;SCN2B;SCN3B;SCN4B;CACNA1G;CACNA1H;CACNA1I;CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA8;CA9;CA10;CA11;CA12;CA13;CA14;MAOB;MAOA;CYP3A4;AOX1;CYP2C19;UGT1A1;CYP3A5 common genes common pathways GO:0042493| response to drug SCN11A;TOP1;CA9;MAOB;UGT1A1 35280:[DB05630 DB00109] DB05630|Sodium stibogluconate TOP1 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 35281:[DB05630 DB00646] DB05630|Sodium stibogluconate TOP1 DB00646|Nystatin CYP3A4;SLCO1B1;SLCO1B3 common genes common pathways 35282:[DB05630 DB00222] DB05630|Sodium stibogluconate TOP1 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0042493| response to drug KCNJ11;ABCC8;TOP1 35283:[DB05630 DB00721] DB05630|Sodium stibogluconate TOP1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0042493| response to drug BCHE;MAOB;SLC6A3;TOP1 35284:[DB05630 DB00273] DB05630|Sodium stibogluconate TOP1 DB00273|Topiramate GABRA1;SCN1A;GRIK1;CA2;CA4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CA1;CA3;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;TOP1 35285:[DB05630 DB14507] DB05630|Sodium stibogluconate TOP1 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0018105| peptidyl-serine phosphorylation TOP1;GSK3B GO:0016310| phosphorylation GSK3B;TOP1 GO:0007623| circadian rhythm TOP1;GSK3B GO:0048511| rhythmic process GSK3B;TOP1 35286:[DB05630 DB01195] DB05630|Sodium stibogluconate TOP1 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways 35287:[DB05630 DB11071] DB05630|Sodium stibogluconate TOP1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug TOP1;PTGS2 35288:[DB05630 DB05232] DB05630|Sodium stibogluconate TOP1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways 35289:[DB05630 DB00056] DB05630|Sodium stibogluconate TOP1 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FCGR2B;TOP1 35290:[DB05630 DB08478] DB05630|Sodium stibogluconate TOP1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug TYMS;TOP1 GO:0007623| circadian rhythm TYMS;TOP1 35291:[DB05630 DB07931] DB05630|Sodium stibogluconate TOP1 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 35292:[DB05630 DB00996] DB05630|Sodium stibogluconate TOP1 DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0042493| response to drug GRIN2A;TOP1 35293:[DB05630 DB08970] DB05630|Sodium stibogluconate TOP1 DB08970|Fluprednidene CYP3A4 common genes common pathways 35294:[DB05630 DB06637] DB05630|Sodium stibogluconate TOP1 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0042493| response to drug CYP2E1;TOP1 35295:[DB05630 DB00722] DB05630|Sodium stibogluconate TOP1 DB00722|Lisinopril ACE common genes common pathways 35296:[DB05630 DB01746] DB05630|Sodium stibogluconate TOP1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways 35297:[DB05630 DB06207] DB05630|Sodium stibogluconate TOP1 DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0042493| response to drug ABCB1;TOP1;ABCB4;ADRA1A GO:0007623| circadian rhythm ABCB4;TOP1 35298:[DB05630 DB01259] DB05630|Sodium stibogluconate TOP1 DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 GO:0007623| circadian rhythm EGFR;TOP1 GO:0016310| phosphorylation ERBB2;TOP1;EGFR GO:0016032| viral reproduction TOP1;TAP1 35299:[DB05630 DB01406] DB05630|Sodium stibogluconate TOP1 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0006338| chromatin remodeling ESR1;TOP1 35300:[DB05630 DB00862] DB05630|Sodium stibogluconate TOP1 DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 35301:[DB05630 DB01215] DB05630|Sodium stibogluconate TOP1 DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;TOP1 35302:[DB05630 DB00448] DB05630|Sodium stibogluconate TOP1 DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0042493| response to drug ABCB1;TOP1;CYP1A1;ABCG2 35303:[DB05630 DB01181] DB05630|Sodium stibogluconate TOP1 DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways 35304:[DB05630 DB06708] DB05630|Sodium stibogluconate TOP1 DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways 35305:[DB05630 DB00672] DB05630|Sodium stibogluconate TOP1 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0042493| response to drug TOP1;ABCC8 35306:[DB05630 DB11079] DB05630|Sodium stibogluconate TOP1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1 35307:[DB05630 DB02300] DB05630|Sodium stibogluconate TOP1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways 35308:[DB05630 DB08437] DB05630|Sodium stibogluconate TOP1 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways 35309:[DB05630 DB12747] DB05630|Sodium stibogluconate TOP1 DB12747|Tertomotide TERT common genes common pathways 35310:[DB05630 DB13170] DB05630|Sodium stibogluconate TOP1 DB13170|Plecanatide GUCY1A2 common genes common pathways 35311:[DB05630 DB01073] DB05630|Sodium stibogluconate TOP1 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0016310| phosphorylation TOP1;DCK GO:0006260| DNA replication TOP1;POLA1;RRM1 GO:0016032| viral reproduction POLA1;TOP1 35312:[DB05630 DB00436] DB05630|Sodium stibogluconate TOP1 DB00436|Bendroflumethiazide SLC12A3;KCNMA1;CA1;CA2;CA4;TPMT common genes common pathways 35313:[DB05630 DB00092] DB05630|Sodium stibogluconate TOP1 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways GO:0016032| viral reproduction FCGR2B;TOP1 35314:[DB05630 DB00953] DB05630|Sodium stibogluconate TOP1 DB00953|Rizatriptan HTR1D;HTR1B;HTR1F;MAOA common genes common pathways GO:0042493| response to drug HTR1B;TOP1 35315:[DB05630 DB13983] DB05630|Sodium stibogluconate TOP1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug TOP1;GABRG3 35316:[DB05630 DB00990] DB05630|Sodium stibogluconate TOP1 DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways 35317:[DB05630 DB11750] DB05630|Sodium stibogluconate TOP1 DB11750|Clobetasol CYP3A4 common genes common pathways 35318:[DB05630 DB00484] DB05630|Sodium stibogluconate TOP1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways 35319:[DB05630 DB05207] DB05630|Sodium stibogluconate TOP1 DB05207|SD118 TNF;IL1R1 common genes common pathways 35320:[DB05630 DB01188] DB05630|Sodium stibogluconate TOP1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;TOP1 35321:[DB05630 DB11737] DB05630|Sodium stibogluconate TOP1 DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0007623| circadian rhythm EGFR;TOP1 GO:0042493| response to drug TOP1;CYP1A2 GO:0016310| phosphorylation EGFR;TOP1 35322:[DB05630 DB06548] DB05630|Sodium stibogluconate TOP1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0016032| viral reproduction TOP1;FDPS 35323:[DB05630 DB11098] DB05630|Sodium stibogluconate TOP1 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways 35324:[DB05630 DB00316] DB05630|Sodium stibogluconate TOP1 DB00316|Acetaminophen PTGS2;PTGS1;FAAH;TRPV1;GSTP1;CYP2E1;CYP1A2;CYP3A4;CYP2D6;CYP1A1;CYP2A6;CYP2C8;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9;SLC22A6;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;TOP1;CYP2E1;UGT1A1;PTGS2 35325:[DB05630 DB09297] DB05630|Sodium stibogluconate TOP1 DB09297|Paritaprevir CYP3A4;CYP3A5;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;TOP1 35326:[DB05630 DB00905] DB05630|Sodium stibogluconate TOP1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways 35327:[DB05630 DB01078] DB05630|Sodium stibogluconate TOP1 DB01078|Deslanoside ATP1A1 common genes common pathways GO:0042493| response to drug TOP1;ATP1A1 35328:[DB05630 DB09139] DB05630|Sodium stibogluconate TOP1 DB09139|Technetium Tc-99m oxidronate ALB common genes common pathways 35329:[DB05630 DB11945] DB05630|Sodium stibogluconate TOP1 DB11945|Avelumab CD274 common genes common pathways 35330:[DB05630 DB01225] DB05630|Sodium stibogluconate TOP1 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways 35331:[DB05630 DB01020] DB05630|Sodium stibogluconate TOP1 DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways 35332:[DB05630 DB01260] DB05630|Sodium stibogluconate TOP1 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0007059| chromosome segregation TOP1;NR3C1 35333:[DB05630 DB05624] DB05630|Sodium stibogluconate TOP1 DB05624|Teverelix GNRHR common genes common pathways 35334:[DB05630 DB11770] DB05630|Sodium stibogluconate TOP1 DB11770|Talinolol CYP2D6 common genes common pathways 35335:[DB05630 DB04711] DB05630|Sodium stibogluconate TOP1 DB04711|Iodipamide ALB common genes common pathways 35336:[DB05630 DB01065] DB05630|Sodium stibogluconate TOP1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0006338| chromatin remodeling TOP1;ESR1 GO:0048511| rhythmic process RORB;TOP1 GO:0007623| circadian rhythm MTNR1A;MTNR1B;TOP1 GO:0042493| response to drug CYP1A2;CYP1A1;TOP1;CALR 35337:[DB05630 DB04830] DB05630|Sodium stibogluconate TOP1 DB04830|Buformin SLC22A1 common genes common pathways 35338:[DB05630 DB06681] DB05630|Sodium stibogluconate TOP1 DB06681|Belatacept CD86;CD80 common genes common pathways GO:0016032| viral reproduction CD86;CD80;TOP1 35339:[DB05630 DB01535] DB05630|Sodium stibogluconate TOP1 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways 35340:[DB05630 DB00679] DB05630|Sodium stibogluconate TOP1 DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0016032| viral reproduction HTR2A;TOP1 GO:0042493| response to drug TOP1;CYP2E1;HTR2A;DRD1;ADRA1A;DRD2 GO:0032922| circadian regulation of gene expression TOP1;DRD2 35341:[DB05630 DB00280] DB05630|Sodium stibogluconate TOP1 DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35342:[DB05630 DB06897] DB05630|Sodium stibogluconate TOP1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways GO:0016310| phosphorylation TOP1;PLK1 GO:0018105| peptidyl-serine phosphorylation TOP1;PLK1 35343:[DB05630 DB01381] DB05630|Sodium stibogluconate TOP1 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0042493| response to drug SLC6A2;TOP1 35344:[DB05630 DB01208] DB05630|Sodium stibogluconate TOP1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0006265| DNA topological change TOP2A;TOP1 GO:0040016| embryonic cleavage TOP2A;TOP1 GO:0048511| rhythmic process TOP2A;TOP1 GO:0016925| protein sumoylation TOP2A;TOP1 GO:0042493| response to drug CYP1A2;ABCC2;ABCB1;TOP1 GO:0007059| chromosome segregation TOP2A;TOP1 35345:[DB05630 DB01283] DB05630|Sodium stibogluconate TOP1 DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways GO:0042493| response to drug PTGS2;TOP1;CYP1A2 35346:[DB05630 DB01166] DB05630|Sodium stibogluconate TOP1 DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0042493| response to drug PDE3A;TOP1;CYP1A2 35347:[DB05630 DB05311] DB05630|Sodium stibogluconate TOP1 DB05311|Ecallantide KLKB1 common genes common pathways 35348:[DB05630 DB01241] DB05630|Sodium stibogluconate TOP1 DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:0048511| rhythmic process TOP1;PPARA GO:0042493| response to drug TOP1;UGT1A1;CYP1A2 GO:0032922| circadian regulation of gene expression TOP1;PPARA 35349:[DB05630 DB00656] DB05630|Sodium stibogluconate TOP1 DB00656|Trazodone HTR2A;HTR2C;SLC6A4;HTR1A;HRH1;ADRA1A;ADRA2A;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ORM1;ABCB1 common genes common pathways GO:0042493| response to drug HTR2A;TOP1;ADRA1A;SLC6A4;ABCB1;HTR2C GO:0007623| circadian rhythm SLC6A4;TOP1 GO:0016032| viral reproduction TOP1;HTR2A 35350:[DB05630 DB00778] DB05630|Sodium stibogluconate TOP1 DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways GO:0042493| response to drug ABCB1;TOP1 35351:[DB05630 DB11475] DB05630|Sodium stibogluconate TOP1 DB11475|Tylosin CYP3A4 common genes common pathways 35352:[DB05630 DB08933] DB05630|Sodium stibogluconate TOP1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes common pathways 35353:[DB05630 DB05465] DB05630|Sodium stibogluconate TOP1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0016310| phosphorylation TOP1;FLT3 35354:[DB05630 DB00181] DB05630|Sodium stibogluconate TOP1 DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways 35355:[DB05630 DB06160] DB05630|Sodium stibogluconate TOP1 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0042493| response to drug TOP1;CYP1A2 35356:[DB05630 DB04839] DB05630|Sodium stibogluconate TOP1 DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways 35357:[DB05630 DB01276] DB05630|Sodium stibogluconate TOP1 DB01276|Exenatide GLP1R;ALB common genes common pathways 35358:[DB05630 DB01949] DB05630|Sodium stibogluconate TOP1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 35359:[DB06817 DB07543] DB06817|Raltegravir pol;UGT1A1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways 35360:[DB06817 DB11730] DB06817|Raltegravir pol;UGT1A1 DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;UGT1A1 GO:0010033| response to organic substance UGT1A1;CDK4 GO:0031100| organ regeneration UGT1A1;CDK4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35361:[DB06817 DB01179] DB06817|Raltegravir pol;UGT1A1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways 35362:[DB06817 DB05127] DB06817|Raltegravir pol;UGT1A1 DB05127|ANA971 TLR7 common genes common pathways 35363:[DB06817 DB01148] DB06817|Raltegravir pol;UGT1A1 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways 35364:[DB06817 DB01594] DB06817|Raltegravir pol;UGT1A1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;UGT1A1 35365:[DB06817 DB00645] DB06817|Raltegravir pol;UGT1A1 DB00645|Dyclonine SCN10A common genes common pathways 35366:[DB06817 DB06725] DB06817|Raltegravir pol;UGT1A1 DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 35367:[DB06817 DB04863] DB06817|Raltegravir pol;UGT1A1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways 35368:[DB06817 DB00232] DB06817|Raltegravir pol;UGT1A1 DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0010033| response to organic substance UGT1A1;CA2 35369:[DB06817 DB00838] DB06817|Raltegravir pol;UGT1A1 DB00838|Clocortolone NR3C1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 35370:[DB06817 DB02789] DB06817|Raltegravir pol;UGT1A1 DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;SULT2B1;NR1I2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35371:[DB06817 DB08911] DB06817|Raltegravir pol;UGT1A1 DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35372:[DB06817 DB00087] DB06817|Raltegravir pol;UGT1A1 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 35373:[DB06817 DB01415] DB06817|Raltegravir pol;UGT1A1 DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 35374:[DB06817 DB09422] DB06817|Raltegravir pol;UGT1A1 DB09422|Soybean oil PPARA common genes common pathways 35375:[DB06817 DB00098] DB06817|Raltegravir pol;UGT1A1 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways 35376:[DB06817 DB00816] DB06817|Raltegravir pol;UGT1A1 DB00816|Orciprenaline ADRB2 common genes common pathways 35377:[DB06817 DB00543] DB06817|Raltegravir pol;UGT1A1 DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0045471| response to ethanol SLC6A3;DRD2;HTR3A;UGT1A1;DRD3;HTR1B GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0006953| acute-phase response UGT1A1;ORM1 GO:0042493| response to drug DRD3;HTR1B;GABRG3;SLC6A4;HTR2C;SLC6A2;UGT1A1;HTR2B;DRD2;ADRA1A;SLC6A3;HTR2A;DRD1 GO:0007586| digestion UGT1A1;CHRM3 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 35378:[DB06817 DB00936] DB06817|Raltegravir pol;UGT1A1 DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0007586| digestion UGT1A1;AKR1C1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 35379:[DB06817 DB03410] DB06817|Raltegravir pol;UGT1A1 DB03410|4-hydroxycoumarin CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35380:[DB06817 DB06685] DB06817|Raltegravir pol;UGT1A1 DB06685|Laquinimod CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35381:[DB06817 DB01618] DB06817|Raltegravir pol;UGT1A1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1 GO:0042493| response to drug UGT1A1;DRD2;HTR2A 35382:[DB06817 DB08894] DB06817|Raltegravir pol;UGT1A1 DB08894|Peginesatide EPOR common genes common pathways 35383:[DB06817 DB05111] DB06817|Raltegravir pol;UGT1A1 DB05111|Fontolizumab IFNG common genes common pathways 35384:[DB06817 DB00617] DB06817|Raltegravir pol;UGT1A1 DB00617|Paramethadione CACNA1I;CYP2E1;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0042493| response to drug UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2E1;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1;UGT1A1;CYP2C8 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;UGT1A1 35385:[DB06817 DB01436] DB06817|Raltegravir pol;UGT1A1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;CYP27B1 35386:[DB06817 DB00866] DB06817|Raltegravir pol;UGT1A1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 35387:[DB06817 DB06233] DB06817|Raltegravir pol;UGT1A1 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0007584| response to nutrient MTOR;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35388:[DB06817 DB00843] DB06817|Raltegravir pol;UGT1A1 DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug HTR2A;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 35389:[DB06817 DB11785] DB06817|Raltegravir pol;UGT1A1 DB11785|Anisodamine CYP2D6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 35390:[DB06817 DB12450] DB06817|Raltegravir pol;UGT1A1 DB12450|Propyl Gallate ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 35391:[DB06817 DB05258] DB06817|Raltegravir pol;UGT1A1 DB05258|Natural alpha interferon IFNAR1 common genes common pathways GO:0032496| response to lipopolysaccharide IFNAR1;UGT1A1 35392:[DB06817 DB09160] DB06817|Raltegravir pol;UGT1A1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 35393:[DB06817 DB12872] DB06817|Raltegravir pol;UGT1A1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0007584| response to nutrient UGT1A1;COL1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;COL1A1 GO:0042493| response to drug COL1A1;UGT1A1 GO:0006953| acute-phase response UGT1A1;F8 35394:[DB06817 DB00135] DB06817|Raltegravir pol;UGT1A1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;TAT GO:0014070| response to organic cyclic compound TH;UGT1A1;TAT GO:0045471| response to ethanol UGT1A1;TH GO:0048545| response to steroid hormone stimulus TH;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TH GO:0042493| response to drug TH;UGT1A1 35395:[DB06817 DB08877] DB06817|Raltegravir pol;UGT1A1 DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;JAK2 35396:[DB06817 DB11641] DB06817|Raltegravir pol;UGT1A1 DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1 GO:0006953| acute-phase response UGT1A1;ORM2;ORM1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35397:[DB06817 DB00654] DB06817|Raltegravir pol;UGT1A1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGFR;UGT1A1 35398:[DB06817 DB00292] DB06817|Raltegravir pol;UGT1A1 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0032870| cellular response to hormone stimulus CYP11B1;UGT1A1;CYP11B2 GO:0042493| response to drug UGT1A1;GABRG3 GO:0008202| steroid metabolic process CYP11B1;UGT1A1;CYP11B2 35399:[DB06817 DB06267] DB06817|Raltegravir pol;UGT1A1 DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008152| metabolic process UGT1A1;PDE5A GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP3A5 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35400:[DB06817 DB06660] DB06817|Raltegravir pol;UGT1A1 DB06660|Saredutant TACR2 common genes common pathways 35401:[DB06817 DB09090] DB06817|Raltegravir pol;UGT1A1 DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35402:[DB06817 DB12836] DB06817|Raltegravir pol;UGT1A1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGER4 35403:[DB06817 DB00139] DB06817|Raltegravir pol;UGT1A1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0007584| response to nutrient OXCT1;UGT1A1 GO:0032870| cellular response to hormone stimulus PLOD3;UGT1A1 GO:0008152| metabolic process ALDH5A1;OXCT2;UGT1A1;SUCLG1;SUCLA2;SUCLG2;OXCT1 GO:0045471| response to ethanol UGT1A1;OXCT1 GO:0008202| steroid metabolic process UGT1A1;HSD17B6 GO:0042493| response to drug UGT1A1;OXCT1 GO:0042594| response to starvation UGT1A1;OXCT1 35404:[DB06817 DB06156] DB06817|Raltegravir pol;UGT1A1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0042493| response to drug SLC6A4;UGT1A1;SLC6A2;SLC6A3 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0045471| response to ethanol UGT1A1;SLC6A3 35405:[DB06817 DB01430] DB06817|Raltegravir pol;UGT1A1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0042493| response to drug UGT1A1;ATP1A1 35406:[DB06817 DB06701] DB06817|Raltegravir pol;UGT1A1 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0045471| response to ethanol SLC6A3;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0042493| response to drug SLC6A4;SLC6A2;UGT1A1;SLC6A3 35407:[DB06817 DB04017] DB06817|Raltegravir pol;UGT1A1 DB04017|Clorgiline MAOA common genes common pathways 35408:[DB06817 DB00854] DB06817|Raltegravir pol;UGT1A1 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 35409:[DB06817 DB14050] DB06817|Raltegravir pol;UGT1A1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0010033| response to organic substance UGT1A1;TRPA1 GO:0042493| response to drug TRPA1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;TRPA1 35410:[DB06817 DB01245] DB06817|Raltegravir pol;UGT1A1 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0042493| response to drug UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0045471| response to ethanol CHRNB2;UGT1A1 35411:[DB06817 DB05785] DB06817|Raltegravir pol;UGT1A1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0010033| response to organic substance UGT1A1;JUN GO:0032496| response to lipopolysaccharide JUN;UGT1A1 GO:0042493| response to drug UGT1A1;JUN GO:0032870| cellular response to hormone stimulus JUN;UGT1A1 GO:0014070| response to organic cyclic compound JUN;UGT1A1 GO:0001889| liver development UGT1A1;RARA;JUN GO:0045471| response to ethanol UGT1A1;RARA 35412:[DB06817 DB00119] DB06817|Raltegravir pol;UGT1A1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0008152| metabolic process PDHB;UGT1A1;PKM;PC;PKLR GO:0045471| response to ethanol UGT1A1;ABAT GO:0001889| liver development UGT1A1;PKM GO:0007584| response to nutrient UGT1A1;PKM;PKLR GO:0042493| response to drug UGT1A1;ABAT GO:0010033| response to organic substance PKM;UGT1A1 GO:0031100| organ regeneration UGT1A1;PKM 35413:[DB06817 DB11201] DB06817|Raltegravir pol;UGT1A1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 35414:[DB06817 DB00392] DB06817|Raltegravir pol;UGT1A1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0045471| response to ethanol GRIN3A;UGT1A1 GO:0042493| response to drug BCHE;UGT1A1 35415:[DB06817 DB00775] DB06817|Raltegravir pol;UGT1A1 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways 35416:[DB06817 DB00768] DB06817|Raltegravir pol;UGT1A1 DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0051384| response to glucocorticoid stimulus UGT1A1;S100B 35417:[DB06817 DB00483] DB06817|Raltegravir pol;UGT1A1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways 35418:[DB06817 DB00300] DB06817|Raltegravir pol;UGT1A1 DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes pol common pathways GO:0042493| response to drug AK4;UGT1A1;NME1;ABCC4;ABCB1;ABCC2 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0010033| response to organic substance ABCC4;UGT1A1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0001889| liver development UGT1A1;AK4 GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 35419:[DB06817 DB00416] DB06817|Raltegravir pol;UGT1A1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways 35420:[DB06817 DB01914] DB06817|Raltegravir pol;UGT1A1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0045471| response to ethanol UGT1A1;SLC2A4 GO:0008152| metabolic process HK1;UGT1A1;GCK 35421:[DB06817 DB06506] DB06817|Raltegravir pol;UGT1A1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 35422:[DB06817 DB00063] DB06817|Raltegravir pol;UGT1A1 DB00063|Eptifibatide ITGB3 common genes common pathways 35423:[DB06817 DB14568] DB06817|Raltegravir pol;UGT1A1 DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2B6;UGT1A1;CYP2C8 GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP3A4;UGT1A1;CYP2C8 GO:0048545| response to steroid hormone stimulus UGT1A1;IDH1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;IDH1 35424:[DB06817 DB09273] DB06817|Raltegravir pol;UGT1A1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0008152| metabolic process UGT1A1;PDE2A GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;ADORA2A;CYP1A2 35425:[DB06817 DB05308] DB06817|Raltegravir pol;UGT1A1 DB05308|ANX-510 TYMS common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0045471| response to ethanol UGT1A1;TYMS GO:0042493| response to drug UGT1A1;TYMS 35426:[DB06817 DB00732] DB06817|Raltegravir pol;UGT1A1 DB00732|Atracurium besylate CHRNA2 common genes common pathways 35427:[DB06817 DB14597] DB06817|Raltegravir pol;UGT1A1 DB14597|Lanadelumab KLKB1 common genes common pathways 35428:[DB06817 DB00945] DB06817|Raltegravir pol;UGT1A1 DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2C9 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP2C9;PRKAA2;PRKAA1 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0007586| digestion UGT1A1;AKR1C1 GO:0032496| response to lipopolysaccharide RPS6KA3;NFKBIA;UGT1A1;NFKB2;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2;TP53;ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;TP53 GO:0071361| cellular response to ethanol UGT1A1;PRKAA1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19 GO:0045471| response to ethanol UGT1A1;TP53 35429:[DB06817 DB06739] DB06817|Raltegravir pol;UGT1A1 DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;TBXA2R GO:1904224| UGT1A9;UGT1A1 GO:0042493| response to drug UGT1A1;TBXA2R GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4;CYP2A6;UGT1A9;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2A6;CYP3A4;UGT1A1;CYP2C8;CYP2C19 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0008152| metabolic process UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0045471| response to ethanol TBXA2R;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9 GO:0052695| cellular glucuronidation UGT1A1;UGT1A9 GO:0007584| response to nutrient TBXA2R;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9 35430:[DB06817 DB00296] DB06817|Raltegravir pol;UGT1A1 DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP2B6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;CYP2B6;CYP3A4;UGT1A1 35431:[DB06817 DB07670] DB06817|Raltegravir pol;UGT1A1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways 35432:[DB06817 DB01079] DB06817|Raltegravir pol;UGT1A1 DB01079|Tegaserod HTR4;HTR2B;HTR2C;HTR2A;CYP1A2;CYP2C8;CYP2D6;CYP2E1;SLC6A4 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug HTR2A;CYP2E1;UGT1A1;HTR2B;HTR2C;CYP1A2;SLC6A4 GO:0017144| drug metabolic process CYP1A2;CYP2D6;UGT1A1;CYP2C8;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2D6;CYP2C8;UGT1A1;CYP2E1 GO:0010033| response to organic substance CYP1A2;SLC6A4;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP1A2;CYP2D6 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 35433:[DB06817 DB06247] DB06817|Raltegravir pol;UGT1A1 DB06247|CX516 GRIA1 common genes common pathways 35434:[DB06817 DB11753] DB06817|Raltegravir pol;UGT1A1 DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;ABCB1;CYP1A2 GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2D6;CYP2C9;CYP2B6;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP2D6;CYP1A2;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A2 35435:[DB06817 DB00266] DB06817|Raltegravir pol;UGT1A1 DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways GO:0017144| drug metabolic process VKORC1;CYP2C9;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;UGT1A1 GO:0007584| response to nutrient NQO1;UGT1A1 GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0045471| response to ethanol UGT1A1;NQO1 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 35436:[DB06817 DB13783] DB06817|Raltegravir pol;UGT1A1 DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0008202| steroid metabolic process UGT2B7;UGT1A1 GO:0042493| response to drug UGT1A1;ABCC1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0052695| cellular glucuronidation UGT2B7;UGT1A1 GO:0008152| metabolic process UGT2B7;UGT1A1 35437:[DB06817 DB00800] DB06817|Raltegravir pol;UGT1A1 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0042493| response to drug ADRA1A;DRD1;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 35438:[DB06817 DB05676] DB06817|Raltegravir pol;UGT1A1 DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol IL2;UGT1A1 GO:0010033| response to organic substance UGT1A1;TNF GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35439:[DB06817 DB06694] DB06817|Raltegravir pol;UGT1A1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug UGT1A1;ADRA1A 35440:[DB06817 DB11587] DB06817|Raltegravir pol;UGT1A1 DB11587|Etafedrine ADRB2 common genes common pathways 35441:[DB06817 DB12555] DB06817|Raltegravir pol;UGT1A1 DB12555|Nelotanserin HTR2A common genes common pathways GO:0042493| response to drug UGT1A1;HTR2A 35442:[DB06817 DB06469] DB06817|Raltegravir pol;UGT1A1 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0031100| organ regeneration FLT3;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35443:[DB06817 DB06737] DB06817|Raltegravir pol;UGT1A1 DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;UGT1A1;UGT2B7 GO:0052695| cellular glucuronidation UGT1A1;UGT2B7 GO:0008152| metabolic process UGT2B7;UGT1A1 35444:[DB06817 DB14583] DB06817|Raltegravir pol;UGT1A1 DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 35445:[DB06817 DB01251] DB06817|Raltegravir pol;UGT1A1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;ABCC8;KCNJ8 GO:0042493| response to drug ABCC8;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;UGT1A1 35446:[DB06817 DB09235] DB06817|Raltegravir pol;UGT1A1 DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35447:[DB06817 DB04725] DB06817|Raltegravir pol;UGT1A1 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:1904224| UGT1A3;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9 GO:0017144| drug metabolic process UGT1A3;CYP2C9;UGT1A1;CYP2C8 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A3;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A3 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 GO:0052695| cellular glucuronidation UGT1A3;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A3 35448:[DB06817 DB00153] DB06817|Raltegravir pol;UGT1A1 DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;CYP27B1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35449:[DB06817 DB00770] DB06817|Raltegravir pol;UGT1A1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0032496| response to lipopolysaccharide PTGER1;UGT1A1;PTGER2 GO:0042493| response to drug UGT1A1;ABCC4 GO:0010033| response to organic substance UGT1A1;ABCC4 35450:[DB06817 DB05956] DB06817|Raltegravir pol;UGT1A1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0045471| response to ethanol GRIN2B;UGT1A1 35451:[DB06817 DB09256] DB06817|Raltegravir pol;UGT1A1 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;TYMS;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2E1;CYP3A5;CYP2A6;CYP1A2 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2E1;CYP2A6;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0045471| response to ethanol TYMS;CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1;CYP2E1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0014070| response to organic cyclic compound CYP1A2;TYMS;UGT1A1 35452:[DB06817 DB09229] DB06817|Raltegravir pol;UGT1A1 DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug ADRA1A;UGT1A1 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35453:[DB06817 DB09078] DB06817|Raltegravir pol;UGT1A1 DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;ABCG2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;FGFR2;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4;CYP1A2;CYP2C9;CYP2B6;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2C8;CYP2C19;AOX1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP1A2;CYP2D6;CYP3A4 GO:0045471| response to ethanol FGFR2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 35454:[DB06817 DB04974] DB06817|Raltegravir pol;UGT1A1 DB04974|AP1903 MTOR common genes common pathways GO:0007584| response to nutrient UGT1A1;MTOR 35455:[DB06817 DB00417] DB06817|Raltegravir pol;UGT1A1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 35456:[DB06817 DB11691] DB06817|Raltegravir pol;UGT1A1 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP3A7;CYP3A5 GO:0017144| drug metabolic process UGT1A1;UGT1A3;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 GO:1904224| UGT1A3;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 GO:0052695| cellular glucuronidation UGT1A1;UGT1A3 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0045471| response to ethanol UGT1A1;OPRM1;OPRK1 GO:0008152| metabolic process UGT1A1;UGT1A3 35457:[DB06817 DB04471] DB06817|Raltegravir pol;UGT1A1 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 35458:[DB06817 DB06311] DB06817|Raltegravir pol;UGT1A1 DB06311|Darapladib PLA2G4A common genes common pathways GO:0008152| metabolic process PLA2G4A;UGT1A1 35459:[DB06817 DB09224] DB06817|Raltegravir pol;UGT1A1 DB09224|Melperone DRD2;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0045471| response to ethanol UGT1A1;DRD2 GO:0042493| response to drug DRD2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;UGT1A1 35460:[DB06817 DB00172] DB06817|Raltegravir pol;UGT1A1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0008152| metabolic process UGT1A1;EPRS 35461:[DB06817 DB00269] DB06817|Raltegravir pol;UGT1A1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 35462:[DB06817 DB12128] DB06817|Raltegravir pol;UGT1A1 DB12128|Ulimorelin GHSR common genes common pathways 35463:[DB06817 DB05420] DB06817|Raltegravir pol;UGT1A1 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0008152| metabolic process UGT1A1;RRM1 35464:[DB06817 DB08931] DB06817|Raltegravir pol;UGT1A1 DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP3A4 GO:0001889| liver development UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A1;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0042493| response to drug CYP1A1;UGT1A1;ABCG2 35465:[DB06817 DB08735] DB06817|Raltegravir pol;UGT1A1 DB08735|R,S-Warfarin alcohol ALB common genes common pathways 35466:[DB06817 DB05025] DB06817|Raltegravir pol;UGT1A1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0045471| response to ethanol UGT1A1;SOD1 GO:0042493| response to drug SOD1;UGT1A1 GO:0010033| response to organic substance SOD1;UGT1A1 35467:[DB06817 DB06824] DB06817|Raltegravir pol;UGT1A1 DB06824|Triethylenetetramine GPC1 common genes common pathways 35468:[DB06817 DB06780] DB06817|Raltegravir pol;UGT1A1 DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35469:[DB06817 DB00991] DB06817|Raltegravir pol;UGT1A1 DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 35470:[DB06817 DB02750] DB06817|Raltegravir pol;UGT1A1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 35471:[DB06817 DB11638] DB06817|Raltegravir pol;UGT1A1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0014070| response to organic cyclic compound G6PD;UGT1A1;LDHA GO:0007584| response to nutrient UGT1A1;LDHA;PKM GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP2C19 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0045471| response to ethanol UGT1A1;G6PD GO:0001889| liver development UGT1A1;HNRNPD;DDX39B;PKM GO:0008152| metabolic process TPI1;UGT2B7;UGT1A1;PGAM1;ALDH7A1;PKM;UGT1A9 GO:0043086| negative regulation of catalytic activity ANXA2;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A1;UGT2B7;UGT1A9 GO:0008202| steroid metabolic process UGT2B7;UGT1A1;CYP2C19;CYP2D6 GO:0071392| cellular response to estradiol stimulus HNRNPD;UGT1A1 GO:0031100| organ regeneration UGT1A1;PKM GO:0017144| drug metabolic process CYP2D6;UGT1A9;CYP2C19;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0010033| response to organic substance PKM;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:1904224| UGT1A1;UGT1A9 GO:0042493| response to drug SRP14;UGT1A1;LDHA;HNRNPD;LGALS1 35472:[DB06817 DB01161] DB06817|Raltegravir pol;UGT1A1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0007584| response to nutrient UGT1A1;BCHE GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0045471| response to ethanol SLC6A3;HTR3A;GRIN3A;UGT1A1 GO:0042493| response to drug SLC6A3;UGT1A1;BCHE 35473:[DB06817 DB07374] DB06817|Raltegravir pol;UGT1A1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0045471| response to ethanol UGT1A1;RPL15 35474:[DB06817 DB14637] DB06817|Raltegravir pol;UGT1A1 DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35475:[DB06817 DB00663] DB06817|Raltegravir pol;UGT1A1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 35476:[DB06817 DB00801] DB06817|Raltegravir pol;UGT1A1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 35477:[DB06817 DB01282] DB06817|Raltegravir pol;UGT1A1 DB01282|Carbetocin OXTR common genes common pathways GO:0042493| response to drug OXTR;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;OXTR GO:0032870| cellular response to hormone stimulus UGT1A1;OXTR GO:0014070| response to organic cyclic compound OXTR;UGT1A1 35478:[DB06817 DB02715] DB06817|Raltegravir pol;UGT1A1 DB02715|Compound 18 ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 35479:[DB06817 DB00226] DB06817|Raltegravir pol;UGT1A1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0042493| response to drug UGT1A1;SLC6A2 35480:[DB06817 DB01321] DB06817|Raltegravir pol;UGT1A1 DB01321|Josamycin rplD;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35481:[DB06817 DB00631] DB06817|Raltegravir pol;UGT1A1 DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0042493| response to drug UGT1A1;ABCG2 GO:0008152| metabolic process UGT1A1;RRM1 35482:[DB06817 DB08361] DB06817|Raltegravir pol;UGT1A1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways 35483:[DB06817 DB07159] DB06817|Raltegravir pol;UGT1A1 DB07159|Tamatinib SYK common genes common pathways 35484:[DB06817 DB09209] DB06817|Raltegravir pol;UGT1A1 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 35485:[DB06817 DB00114] DB06817|Raltegravir pol;UGT1A1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0008210| estrogen metabolic process UGT1A1;SGPL1 GO:0042493| response to drug GAD2;UGT1A1;GAD1;SRR;ABAT GO:0032496| response to lipopolysaccharide SRR;UGT1A1 GO:0008152| metabolic process GCAT;ALAS2;CBS;PYGL;FTCD;SRR;SPTLC2;BCAT1;UGT1A1;ALAS1;BCAT2;SPTLC3;PYGB;PDXP;PYGM GO:0045471| response to ethanol UGT1A1;GOT2;ABAT GO:0014070| response to organic cyclic compound UGT1A1;TAT;SRR GO:0051384| response to glucocorticoid stimulus UGT1A1;AGXT;GOT1;TAT 35486:[DB06817 DB11091] DB06817|Raltegravir pol;UGT1A1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0042493| response to drug UGT1A1;CAT GO:0045471| response to ethanol CAT;UGT1A1 GO:0008152| metabolic process ALPPL2;UGT1A1 35487:[DB06817 DB13179] DB06817|Raltegravir pol;UGT1A1 DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;UGT1A1 GO:0042493| response to drug UGT1A1;ABCB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35488:[DB06817 DB01435] DB06817|Raltegravir pol;UGT1A1 DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP1A2;CYP2C9;CYP2B6;CYP2D6;UGT1A1;CYP2C8;CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;UGT1A1;CYP2E1;CYP2A6;CYP3A4;CYP2D6;CYP2B6;CYP2C9;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1;PTGS2;CYP2E1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;CYP1A2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4;CYP1A2;CYP2D6 GO:0045471| response to ethanol UGT1A1;CYP2E1 35489:[DB06817 DB11640] DB06817|Raltegravir pol;UGT1A1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0008152| metabolic process NAT2;UGT1A1;NAT1 35490:[DB06817 DB00197] DB06817|Raltegravir pol;UGT1A1 DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes UGT1A1 common pathways GO:0042167| heme catabolic process UGT1A4;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A8;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0014070| response to organic cyclic compound PPARG;CYP1A1;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A3;UGT1A9;UGT1A7;UGT1A8 GO:0007584| response to nutrient ACSL4;UGT1A1;PPARG GO:0051552| flavone metabolic process UGT1A1;UGT1A10;UGT1A9;UGT1A7;UGT1A8 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A1;CYP2C19;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1;GSTP1 GO:0008152| metabolic process UGT1A4;GSTP1;ACSL4;UGT1A10;UGT2B7;UGT1A1;UGT2B15;UGT1A6;UGT1A8;UGT1A7;UGT1A9;UGT1A3 GO:0071361| cellular response to ethanol UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1;UGT1A7;UGT1A8 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A6;UGT1A4;UGT1A10;UGT1A9;UGT1A3;UGT1A8;UGT1A7 GO:0052695| cellular glucuronidation UGT2B15;UGT1A1;UGT1A6;UGT1A4;UGT1A10;UGT2B7;UGT1A9;UGT1A3;UGT1A8;UGT1A7 GO:0006789| bilirubin conjugation UGT1A1;UGT1A4 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;UGT1A8;CYP3A4;CYP1A1;CYP3A5;CYP3A7;UGT2B7;UGT2B15;UGT1A1;CYP2C19;CYP2C8 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0031100| organ regeneration GSTP1;UGT1A1;PPARG GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A4;CYP1A1;UGT1A10;CYP2C8;CYP2C19;UGT1A1;UGT1A6;UGT1A8;CYP2B6;CYP2C9;UGT1A7;UGT1A9;UGT1A3;CYP3A4 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A6;UGT1A4;UGT1A10;UGT1A9;UGT1A3;UGT1A8;UGT1A7 GO:0045922| negative regulation of fatty acid metabolic process UGT1A6;UGT1A1;UGT1A10;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A8 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A6;UGT1A4;UGT1A10;UGT1A9;UGT1A3;UGT1A8;UGT1A7 GO:0010033| response to organic substance PPARD;PPARG;CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:1904224| UGT1A8;UGT1A7;UGT1A9;UGT1A3;UGT1A4;UGT1A10;UGT1A1;UGT1A6 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug PPARG;UGT1A1;CYP1A1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 35491:[DB06817 DB01186] DB06817|Raltegravir pol;UGT1A1 DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0045471| response to ethanol DRD3;HTR1B;DRD2;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0042493| response to drug HTR2B;UGT1A1;DRD1;HTR2A;ADRA1A;DRD2;HTR1B;DRD3;HTR2C 35492:[DB06817 DB11569] DB06817|Raltegravir pol;UGT1A1 DB11569|Ixekizumab IL17A common genes common pathways 35493:[DB06817 DB01130] DB06817|Raltegravir pol;UGT1A1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35494:[DB06817 DB06151] DB06817|Raltegravir pol;UGT1A1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0010033| response to organic substance UGT1A1;CHUK GO:0042493| response to drug UGT1A1;GRIN2A;CHUK GO:0032496| response to lipopolysaccharide CHUK;UGT1A1 GO:0045471| response to ethanol GRIN3A;UGT1A1;GRIN1;GRIN2A;GRIN2B GO:0008152| metabolic process ACY1;UGT1A1 35495:[DB06817 DB03704] DB06817|Raltegravir pol;UGT1A1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;ADH5 35496:[DB06817 DB06634] DB06817|Raltegravir pol;UGT1A1 DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0014070| response to organic cyclic compound TACR1;UGT1A1 GO:0045471| response to ethanol TACR1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35497:[DB06817 DB09089] DB06817|Raltegravir pol;UGT1A1 DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0007586| digestion UGT1A1;CHRM3 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0071361| cellular response to ethanol KCNMB1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol OPRM1;UGT1A1 35498:[DB06817 DB09570] DB06817|Raltegravir pol;UGT1A1 DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;CYP3A4;UGT1A1;CYP2C19 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP2D6;UGT1A1;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2C8;CYP2C19;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 35499:[DB06817 DB08815] DB06817|Raltegravir pol;UGT1A1 DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol DRD2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug HTR2A;DRD2;UGT1A1 35500:[DB06817 DB01629] DB06817|Raltegravir pol;UGT1A1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0045471| response to ethanol UGT1A1;SOD1 GO:0042493| response to drug SOD1;UGT1A1 GO:0010033| response to organic substance SOD1;UGT1A1 35501:[DB06817 DB12478] DB06817|Raltegravir pol;UGT1A1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD2;UGT1A1;DRD3 GO:0045471| response to ethanol DRD3;UGT1A1;DRD2 35502:[DB06817 DB00208] DB06817|Raltegravir pol;UGT1A1 DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2E1;CYP1A1;CYP3A4;CYP1A2;CYP2D6 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP2E1;UGT1A1;CYP2C8;CYP2C19;CYP2B6;CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2E1;CYP1A1;CYP3A4;CYP1A2;CYP2D6;CYP2C9;CYP2B6 GO:0010033| response to organic substance UGT1A1;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;MPO;CYP1A1 GO:0042493| response to drug CYP1A1;CYP2E1;UGT1A1;CYP1A2 35503:[DB06817 DB01021] DB06817|Raltegravir pol;UGT1A1 DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways GO:0042493| response to drug UGT1A1;ATP1A1 GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:0010033| response to organic substance CA2;UGT1A1 35504:[DB06817 DB00824] DB06817|Raltegravir pol;UGT1A1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0042493| response to drug UGT1A1;ADORA2A 35505:[DB06817 DB11834] DB06817|Raltegravir pol;UGT1A1 DB11834|Guselkumab IL23A common genes common pathways 35506:[DB06817 DB08906] DB06817|Raltegravir pol;UGT1A1 DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35507:[DB06817 DB11124] DB06817|Raltegravir pol;UGT1A1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0042493| response to drug ADRA1A;UGT1A1 35508:[DB06817 DB06587] DB06817|Raltegravir pol;UGT1A1 DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0007586| digestion UGT1A1;MLNR GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 35509:[DB06817 DB07402] DB06817|Raltegravir pol;UGT1A1 DB07402|Azapropazone ALB common genes common pathways 35510:[DB06817 DB02209] DB06817|Raltegravir pol;UGT1A1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways 35511:[DB06817 DB05749] DB06817|Raltegravir pol;UGT1A1 DB05749|MPI-674 CYP19A1 common genes common pathways 35512:[DB06817 DB09363] DB06817|Raltegravir pol;UGT1A1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;MAOB GO:0042493| response to drug SLC6A2;UGT1A1;MAOB GO:0045471| response to ethanol MAOB;UGT1A1 35513:[DB06817 DB04888] DB06817|Raltegravir pol;UGT1A1 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1 GO:0042493| response to drug DRD2;UGT1A1 35514:[DB06817 DB14010] DB06817|Raltegravir pol;UGT1A1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0042493| response to drug HTR2A;UGT1A1 35515:[DB06817 DB01256] DB06817|Raltegravir pol;UGT1A1 DB01256|Retapamulin rplC;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35516:[DB06817 DB14509] DB06817|Raltegravir pol;UGT1A1 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways 35517:[DB06817 DB04836] DB06817|Raltegravir pol;UGT1A1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0042493| response to drug SLC6A4;SLC6A2;UGT1A1 GO:0010033| response to organic substance SLC6A4;UGT1A1 35518:[DB06817 DB00211] DB06817|Raltegravir pol;UGT1A1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 GO:0042493| response to drug ADRA1A;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 35519:[DB06817 DB08895] DB06817|Raltegravir pol;UGT1A1 DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0032496| response to lipopolysaccharide JAK2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 35520:[DB06817 DB01324] DB06817|Raltegravir pol;UGT1A1 DB01324|Polythiazide SLC12A3 common genes common pathways 35521:[DB06817 DB14539] DB06817|Raltegravir pol;UGT1A1 DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008152| metabolic process HSD3B1;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;ANXA1;HSD11B2 GO:0032870| cellular response to hormone stimulus UGT1A1;CYP11B2;CYP11B1 GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0042493| response to drug UGT1A1;ABCG2;ABCB1;HSD11B2;ANXA1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1;ANXA1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP11B2;CYP3A5;CYP11B1;CYP3A7;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0048545| response to steroid hormone stimulus HSD11B2;UGT1A1 35522:[DB06817 DB05885] DB06817|Raltegravir pol;UGT1A1 DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35523:[DB06817 DB11127] DB06817|Raltegravir pol;UGT1A1 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways 35524:[DB06817 DB09204] DB06817|Raltegravir pol;UGT1A1 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0006953| acute-phase response UGT1A1;ORM1 GO:0042493| response to drug ADRA1A;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 35525:[DB06817 DB08826] DB06817|Raltegravir pol;UGT1A1 DB08826|Deferiprone UGT1A6 common genes common pathways GO:1904224| UGT1A1;UGT1A6 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A6 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A6 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A6 GO:0017144| drug metabolic process UGT1A6;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A6 GO:0052695| cellular glucuronidation UGT1A1;UGT1A6 GO:0008152| metabolic process UGT1A6;UGT1A1 35526:[DB06817 DB01205] DB06817|Raltegravir pol;UGT1A1 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 35527:[DB06817 DB09185] DB06817|Raltegravir pol;UGT1A1 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug SLC6A2;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 35528:[DB06817 DB06013] DB06817|Raltegravir pol;UGT1A1 DB06013|Aldoxorubicin TOP2A common genes common pathways 35529:[DB06817 DB05968] DB06817|Raltegravir pol;UGT1A1 DB05968|PR-104 TNF common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0010033| response to organic substance TNF;UGT1A1 35530:[DB06817 DB14004] DB06817|Raltegravir pol;UGT1A1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0010033| response to organic substance IL12B;UGT1A1 35531:[DB06817 DB09148] DB06817|Raltegravir pol;UGT1A1 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0017144| drug metabolic process CYP4F2;UGT1A1 35532:[DB06817 DB00407] DB06817|Raltegravir pol;UGT1A1 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways GO:0007584| response to nutrient SERPINC1;UGT1A1 35533:[DB06817 DB05014] DB06817|Raltegravir pol;UGT1A1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PDGFRB GO:0031100| organ regeneration UGT1A1;FLT3 GO:0042493| response to drug UGT1A1;RET GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;FLT3 35534:[DB06817 DB09378] DB06817|Raltegravir pol;UGT1A1 DB09378|Fluprednisolone CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35535:[DB06817 DB12026] DB06817|Raltegravir pol;UGT1A1 DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug UGT1A1;ABCG2;CYP1A2;ABCB1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C8 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 35536:[DB06817 DB00980] DB06817|Raltegravir pol;UGT1A1 DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP1A2;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP1A2;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP1A2;CYP3A4;UGT1A1;CYP2C19 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 35537:[DB06817 DB00241] DB06817|Raltegravir pol;UGT1A1 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 35538:[DB06817 DB00467] DB06817|Raltegravir pol;UGT1A1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 35539:[DB06817 DB08837] DB06817|Raltegravir pol;UGT1A1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways 35540:[DB06817 DB03336] DB06817|Raltegravir pol;UGT1A1 DB03336|BIA COMT common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;COMT GO:0032496| response to lipopolysaccharide COMT;UGT1A1 GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0042493| response to drug UGT1A1;COMT 35541:[DB06817 DB12693] DB06817|Raltegravir pol;UGT1A1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0042493| response to drug UGT1A1;HTR2A GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 35542:[DB06817 DB09124] DB06817|Raltegravir pol;UGT1A1 DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35543:[DB06817 DB00013] DB06817|Raltegravir pol;UGT1A1 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways 35544:[DB06817 DB00206] DB06817|Raltegravir pol;UGT1A1 DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0008202| steroid metabolic process CYP3A5;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1 GO:0042493| response to drug ABCB1;ABCC2;UGT1A1 35545:[DB06817 DB06446] DB06817|Raltegravir pol;UGT1A1 DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug HTR2A;UGT1A1;HTR2C GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35546:[DB06817 DB09383] DB06817|Raltegravir pol;UGT1A1 DB09383|Meprednisone CYP3A4;ALB common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35547:[DB06817 DB01403] DB06817|Raltegravir pol;UGT1A1 DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP2D6 GO:0007586| digestion CHRM3;UGT1A1 GO:0042493| response to drug UGT1A1;CYP2E1;HTR2A;DRD1;DRD2;ADRA1A;DRD3;HTR2C GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0046483| heterocycle metabolic process CYP2D6;CYP2E1;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1;DRD2;DRD3 35548:[DB06817 DB14009] DB06817|Raltegravir pol;UGT1A1 DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0031100| organ regeneration UGT1A1;PPARG GO:0017144| drug metabolic process CYP1A1;UGT1A1;CYP2C19;CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process HMGCR;UGT1A1;CYP2C19;CYP3A7;CYP1A1;CYP17A1;CYP3A5;CYP3A4;CYP1B1;CYP1A2;CYP2C9;CYP2D6 GO:0010033| response to organic substance PTGS2;UGT1A1;SOD1;CYP1A1;TRPA1;PPARG;CYP1A2 GO:0042594| response to starvation PPARG;UGT1A1;ACAT1 GO:0032496| response to lipopolysaccharide OPRM1;CNR1;CYP1A2;IDO1;UGT1A1;PTGS2;CYP1A1;CNR2 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0042493| response to drug CYP1A1;HTR2A;SOD1;ABCG2;UGT1A1;ABCC1;SMPD1;PTGS2;CAT;CYP1A2;PPARG;TRPA1 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0007584| response to nutrient UGT1A1;HMGCR;PPARG;CNR1 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;TRPA1;CYP1A1;ACAT1;UGT1A1;AANAT;PTGS2 GO:0008152| metabolic process ACAT1;UGT1A1;SMPD1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;UGT1A1;CYP2D6;CYP1A2;CYP3A4 GO:0045471| response to ethanol SOD1;UGT1A1;HMGCR;CAT;OPRM1;CNR1 GO:0001889| liver development ACAT1;CYP1A1;UGT1A1 35549:[DB06817 DB00137] DB06817|Raltegravir pol;UGT1A1 DB00137|Lutein ALB common genes common pathways 35550:[DB06817 DB08954] DB06817|Raltegravir pol;UGT1A1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0045471| response to ethanol GRIN2B;UGT1A1;GRIN1 35551:[DB06817 DB11338] DB06817|Raltegravir pol;UGT1A1 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0048545| response to steroid hormone stimulus COL1A1;UGT1A1 GO:0042493| response to drug COL1A1;UGT1A1 GO:0032496| response to lipopolysaccharide VCAM1;CXCL10;UGT1A1 GO:0007584| response to nutrient UGT1A1;VCAM1;COL1A1 GO:0045471| response to ethanol UGT1A1;VCAM1 35552:[DB06817 DB00505] DB06817|Raltegravir pol;UGT1A1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 35553:[DB06817 DB00166] DB06817|Raltegravir pol;UGT1A1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0032496| response to lipopolysaccharide LIAS;UGT1A1 GO:0042493| response to drug POR;UGT1A1 GO:0007584| response to nutrient UGT1A1;POR 35554:[DB06817 DB11635] DB06817|Raltegravir pol;UGT1A1 DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0007584| response to nutrient ABCA1;ABCG8;UGT1A1;ABCG5;TTPA GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process ABCA1;CYP3A4;APOBR;NPC1L1;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP4F2;UGT1A1 GO:0042493| response to drug ABCA1;ABCB1;ABCG8;UGT1A1;NPC1L1;ABCG5 35555:[DB06817 DB00837] DB06817|Raltegravir pol;UGT1A1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways 35556:[DB06817 DB06785] DB06817|Raltegravir pol;UGT1A1 DB06785|Ganirelix GNRHR common genes common pathways 35557:[DB06817 DB13620] DB06817|Raltegravir pol;UGT1A1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0032496| response to lipopolysaccharide ATP4B;UGT1A1 GO:0042493| response to drug ATP1A1;UGT1A1 35558:[DB06817 DB14071] DB06817|Raltegravir pol;UGT1A1 DB14071|Desmethylsertraline ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 35559:[DB06817 DB01173] DB06817|Raltegravir pol;UGT1A1 DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2B6;CYP3A4;CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2B6;UGT1A1;CYP2E1 GO:0042493| response to drug CYP2E1;SLC6A2;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0045471| response to ethanol CYP2E1;GRIN1;GRIN3A;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP2E1;UGT1A1 35560:[DB06817 DB06706] DB06817|Raltegravir pol;UGT1A1 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0042493| response to drug ADRA1A;UGT1A1 35561:[DB06817 DB11792] DB06817|Raltegravir pol;UGT1A1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A5;CYP3A7;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35562:[DB06817 DB03856] DB06817|Raltegravir pol;UGT1A1 DB03856|L-Eflornithine ODC1 common genes common pathways 35563:[DB06817 DB07339] DB06817|Raltegravir pol;UGT1A1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways 35564:[DB06817 DB04956] DB06817|Raltegravir pol;UGT1A1 DB04956|Afelimomab TNF common genes common pathways GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0010033| response to organic substance UGT1A1;TNF 35565:[DB06817 DB00423] DB06817|Raltegravir pol;UGT1A1 DB00423|Methocarbamol CA1 common genes common pathways 35566:[DB06817 DB06726] DB06817|Raltegravir pol;UGT1A1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 35567:[DB06817 DB11477] DB06817|Raltegravir pol;UGT1A1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 35568:[DB06817 DB11274] DB06817|Raltegravir pol;UGT1A1 DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0045471| response to ethanol DRD3;UGT1A1;DRD2 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug DRD3;DRD2;DRD1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35569:[DB06817 DB00274] DB06817|Raltegravir pol;UGT1A1 DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 35570:[DB06817 DB01352] DB06817|Raltegravir pol;UGT1A1 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35571:[DB06817 DB06468] DB06817|Raltegravir pol;UGT1A1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0014070| response to organic cyclic compound SLC9A1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;MPO 35572:[DB06817 DB14185] DB06817|Raltegravir pol;UGT1A1 DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 GO:0042493| response to drug HTR2C;DRD3;HTR1B;DRD2;ADRA1A;HTR2A;DRD1;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0045471| response to ethanol UGT1A1;HTR3A;DRD2;DRD3;HTR1B GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 35573:[DB06817 DB01044] DB06817|Raltegravir pol;UGT1A1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 35574:[DB06817 DB00759] DB06817|Raltegravir pol;UGT1A1 DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways GO:0043086| negative regulation of catalytic activity PRNP;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008152| metabolic process PRNP;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35575:[DB06817 DB04894] DB06817|Raltegravir pol;UGT1A1 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound TACR1;UGT1A1 GO:0007584| response to nutrient SSTR2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0045471| response to ethanol TACR1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;SSTR2 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;SSTR2;SSTR5 GO:0007586| digestion UGT1A1;SSTR2 GO:0042594| response to starvation UGT1A1;SSTR2 35576:[DB06817 DB01206] DB06817|Raltegravir pol;UGT1A1 DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 35577:[DB06817 DB09079] DB06817|Raltegravir pol;UGT1A1 DB09079|Nintedanib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FLT3;LCK;LYN;SRC;CYP3A4;ABCB1 common genes common pathways GO:0032496| response to lipopolysaccharide FGFR2;UGT1A1 GO:0042493| response to drug LYN;ABCB1;SRC;UGT1A1;LCK GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0031100| organ regeneration FLT3;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol UGT1A1;FGFR2 GO:0014070| response to organic cyclic compound LYN;UGT1A1 35578:[DB06817 DB12001] DB06817|Raltegravir pol;UGT1A1 DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0001889| liver development UGT1A1;OTC GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0031100| organ regeneration CDK4;UGT1A1 GO:0010033| response to organic substance CDK4;UGT1A1 GO:0042493| response to drug ABCB1;OTC;ABCG2;UGT1A1;CDK4 GO:0006953| acute-phase response UGT1A1;ORM2;ORM1 35579:[DB06817 DB07525] DB06817|Raltegravir pol;UGT1A1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways 35580:[DB06817 DB08953] DB06817|Raltegravir pol;UGT1A1 DB08953|Indalpine CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35581:[DB06817 DB05339] DB06817|Raltegravir pol;UGT1A1 DB05339|MN-305 HTR1A common genes common pathways 35582:[DB06817 DB00110] DB06817|Raltegravir pol;UGT1A1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 35583:[DB06817 DB00312] DB06817|Raltegravir pol;UGT1A1 DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0045471| response to ethanol GRIN1;GRIN3A;UGT1A1;GRIN2B;GRIN2A GO:0042493| response to drug GABRG3;GRIN2A;UGT1A1 GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;NR1I2;CYP2C19;UGT1A1 35584:[DB06817 DB01094] DB06817|Raltegravir pol;UGT1A1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;SOAT2;SOAT1;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1;ABCG2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 35585:[DB06817 DB05139] DB06817|Raltegravir pol;UGT1A1 DB05139|CR002 PDGFD common genes common pathways 35586:[DB06817 DB11275] DB06817|Raltegravir pol;UGT1A1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0045471| response to ethanol DRD3;DRD2;UGT1A1 GO:0042493| response to drug DRD3;UGT1A1;DRD2;DRD1 35587:[DB06817 DB00650] DB06817|Raltegravir pol;UGT1A1 DB00650|Leucovorin SLC22A8 common genes common pathways 35588:[DB06817 DB08980] DB06817|Raltegravir pol;UGT1A1 DB08980|Fendiline CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 35589:[DB06817 DB00111] DB06817|Raltegravir pol;UGT1A1 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 35590:[DB06817 DB13933] DB06817|Raltegravir pol;UGT1A1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0006953| acute-phase response UGT1A1;F8 GO:0031100| organ regeneration F7;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;F7 35591:[DB06817 DB13948] DB06817|Raltegravir pol;UGT1A1 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0042493| response to drug UGT1A1;HTR2A 35592:[DB06817 DB01466] DB06817|Raltegravir pol;UGT1A1 DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0045471| response to ethanol OPRM1;UGT1A1 GO:0007584| response to nutrient UGT1A1;POR GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:0042493| response to drug POR;UGT1A1 GO:0017144| drug metabolic process CYP2B6;CYP2D6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP2B6;CYP2D6;CYP3A4;UGT1A1 35593:[DB06817 DB00568] DB06817|Raltegravir pol;UGT1A1 DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;UGT1A1;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0045471| response to ethanol UGT1A1;DRD2 GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2D6;CYP2B6;CYP2C9;CYP1A2;UGT1A1;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C9;CYP2B6;UGT1A1;CYP1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1;CYP1A2 GO:0007586| digestion CHRM3;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;CYP1A1 GO:0042493| response to drug UGT1A1;CYP1A1;DRD2;DRD1;CYP1A2 35594:[DB06817 DB07768] DB06817|Raltegravir pol;UGT1A1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0007586| digestion AKR1C2;AKR1C1;UGT1A1 GO:0008202| steroid metabolic process AKR1C2;UGT1A1 35595:[DB06817 DB05482] DB06817|Raltegravir pol;UGT1A1 DB05482|7-ethyl-10-hydroxycamptothecin TOP1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug UGT1A1;TOP1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35596:[DB06817 DB01053] DB06817|Raltegravir pol;UGT1A1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 35597:[DB06817 DB03907] DB06817|Raltegravir pol;UGT1A1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0014070| response to organic cyclic compound COMT;UGT1A1 GO:0042493| response to drug COMT;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0032496| response to lipopolysaccharide COMT;UGT1A1 35598:[DB06817 DB12773] DB06817|Raltegravir pol;UGT1A1 DB12773|Sifalimumab IFNA2 common genes common pathways 35599:[DB06817 DB01645] DB06817|Raltegravir pol;UGT1A1 DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCC1;ABCG2;PTK2B;ABCB1;CYP1A2 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance AKT1;UGT1A1;CYP1A2 GO:0071392| cellular response to estradiol stimulus UGT1A1;GPER1;ESR1;ESR2 GO:0008202| steroid metabolic process CYP1B1;CYP3A4;CYP2C9;NR1I2;CYP1A2;UGT1A1;CYP2C8 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2C9;CYP1A2 GO:0045471| response to ethanol UGT1A1;PTK2B GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1;NCOA1 35600:[DB06817 DB06372] DB06817|Raltegravir pol;UGT1A1 DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways GO:0006953| acute-phase response UGT1A1;IL1RN GO:0032496| response to lipopolysaccharide UGT1A1;IL1B GO:0051384| response to glucocorticoid stimulus IL1RN;UGT1A1 35601:[DB06817 DB08814] DB06817|Raltegravir pol;UGT1A1 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0008152| metabolic process UGT1A1;PDE10A GO:0032496| response to lipopolysaccharide UGT1A1;NOS2 35602:[DB06817 DB00365] DB06817|Raltegravir pol;UGT1A1 DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;ABCC2;CYP1A2;ABCC1;UGT1A1 GO:0032496| response to lipopolysaccharide ABCC2;CYP1A2;UGT1A1 35603:[DB06817 DB11619] DB06817|Raltegravir pol;UGT1A1 DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35604:[DB06817 DB09272] DB06817|Raltegravir pol;UGT1A1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0042493| response to drug ABCC2;UGT1A1 GO:0032496| response to lipopolysaccharide ABCC2;OPRM1;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 35605:[DB06817 DB04871] DB06817|Raltegravir pol;UGT1A1 DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes common pathways GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2D6;CYP2B6;CYP2A6;CYP3A4;CYP1A1;CYP2C19;UGT1A1 GO:0017144| drug metabolic process CYP1A1;FMO1;CYP2C19;UGT1A1;CYP2D6;CYP2B6;CYP1A2;CYP3A4;CYP2A6 GO:0042493| response to drug HTR2C;CYP1A2;CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;FMO1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP1A1;CYP3A4;CYP2D6;CYP1A2 35606:[DB06817 DB00657] DB06817|Raltegravir pol;UGT1A1 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0045471| response to ethanol CHRNB2;UGT1A1 35607:[DB06817 DB08844] DB06817|Raltegravir pol;UGT1A1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways GO:0008152| metabolic process PYGL;UGT1A1 35608:[DB06817 DB01018] DB06817|Raltegravir pol;UGT1A1 DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19 35609:[DB06817 DB01405] DB06817|Raltegravir pol;UGT1A1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 35610:[DB06817 DB05361] DB06817|Raltegravir pol;UGT1A1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;F2R GO:0007584| response to nutrient SERPINC1;UGT1A1 35611:[DB06817 DB08875] DB06817|Raltegravir pol;UGT1A1 DB08875|Cabozantinib MET;KDR;RET;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C9;CYP3A4 GO:0042493| response to drug RET;UGT1A1 35612:[DB06817 DB01409] DB06817|Raltegravir pol;UGT1A1 DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0007586| digestion CHRM3;UGT1A1 35613:[DB06817 DB00812] DB06817|Raltegravir pol;UGT1A1 DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2C9 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2C9 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 35614:[DB06817 DB00865] DB06817|Raltegravir pol;UGT1A1 DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0045471| response to ethanol UGT1A1;SLC6A3 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0007584| response to nutrient POR;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0042493| response to drug POR;ADRA1A;SLC6A3;UGT1A1 GO:0017144| drug metabolic process CYP2B6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;UGT1A1 35615:[DB06817 DB06231] DB06817|Raltegravir pol;UGT1A1 DB06231|Caldaret SLC8A1 common genes common pathways GO:0042493| response to drug UGT1A1;SLC8A1 GO:0007584| response to nutrient SLC8A1;UGT1A1 35616:[DB06817 DB13941] DB06817|Raltegravir pol;UGT1A1 DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2E1;CYP3A4;CYP2B6;CYP2C9 GO:0008202| steroid metabolic process CYP2E1;CYP2C19;UGT1A1;CYP2C9;CYP2B6;CYP3A4 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1;CYP2E1 35617:[DB06817 DB00160] DB06817|Raltegravir pol;UGT1A1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0045471| response to ethanol UGT1A1;ABAT GO:0051384| response to glucocorticoid stimulus UGT1A1;AGXT GO:0042493| response to drug ABAT;UGT1A1 35618:[DB06817 DB00596] DB06817|Raltegravir pol;UGT1A1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 35619:[DB06817 DB00094] DB06817|Raltegravir pol;UGT1A1 DB00094|Urofollitropin FSHR common genes common pathways 35620:[DB06817 DB00189] DB06817|Raltegravir pol;UGT1A1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;UGT1A1 35621:[DB06817 DB09395] DB06817|Raltegravir pol;UGT1A1 DB09395|Sodium acetate ACSS2 common genes common pathways GO:0008152| metabolic process UGT1A1;ACSS2 35622:[DB06817 DB01366] DB06817|Raltegravir pol;UGT1A1 DB01366|Procaterol ADRB2 common genes common pathways 35623:[DB06817 DB00385] DB06817|Raltegravir pol;UGT1A1 DB00385|Valrubicin TOP2A common genes common pathways 35624:[DB06817 DB14596] DB06817|Raltegravir pol;UGT1A1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35625:[DB06817 DB01656] DB06817|Raltegravir pol;UGT1A1 DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35626:[DB06817 DB01440] DB06817|Raltegravir pol;UGT1A1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 35627:[DB06817 DB08874] DB06817|Raltegravir pol;UGT1A1 DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35628:[DB06817 DB13036] DB06817|Raltegravir pol;UGT1A1 DB13036|Ramatroban PTGDR2 common genes common pathways 35629:[DB06817 DB01144] DB06817|Raltegravir pol;UGT1A1 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways GO:0010033| response to organic substance CA2;UGT1A1 GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:0045471| response to ethanol UGT1A1;CA3 35630:[DB06817 DB12781] DB06817|Raltegravir pol;UGT1A1 DB12781|Balaglitazone CYP3A4;CYP2C8 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35631:[DB06817 DB01623] DB06817|Raltegravir pol;UGT1A1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP2D6 GO:0045471| response to ethanol UGT1A1;DRD2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;DRD2;DRD1;HTR2A;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP1A2 35632:[DB06817 DB00033] DB06817|Raltegravir pol;UGT1A1 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 35633:[DB06817 DB13997] DB06817|Raltegravir pol;UGT1A1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A3;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:1904224| UGT1A1;UGT1A3 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 GO:0052695| cellular glucuronidation UGT1A3;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A3 GO:0008152| metabolic process UGT1A1;UGT1A3 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35634:[DB06817 DB14582] DB06817|Raltegravir pol;UGT1A1 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways GO:0006953| acute-phase response UGT1A1;ORM2;ORM1 35635:[DB06817 DB00691] DB06817|Raltegravir pol;UGT1A1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 35636:[DB06817 DB05442] DB06817|Raltegravir pol;UGT1A1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0032496| response to lipopolysaccharide IL1B;UGT1A1 35637:[DB06817 DB09060] DB06817|Raltegravir pol;UGT1A1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0042493| response to drug ABCC2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 35638:[DB06817 DB00434] DB06817|Raltegravir pol;UGT1A1 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 GO:1904224| UGT1A3;UGT1A1 GO:0042493| response to drug HTR2A;UGT1A1;HTR2C GO:0017144| drug metabolic process UGT1A3;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A3;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0008152| metabolic process UGT1A3;UGT1A1 GO:0052695| cellular glucuronidation UGT1A3;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 35639:[DB06817 DB00949] DB06817|Raltegravir pol;UGT1A1 DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0042493| response to drug CYP2E1;UGT1A1;GRIN2A GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4;CYP2C9 GO:0045471| response to ethanol GRIN2B;GRIN2A;CYP2E1;GRIN3A;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4 35640:[DB06817 DB08912] DB06817|Raltegravir pol;UGT1A1 DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;CYP2B6;CYP2C9 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2B6;CYP2C9;CYP3A4 GO:0042493| response to drug ABCG2;UGT1A1;ABCB1 GO:0032870| cellular response to hormone stimulus SIK1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35641:[DB06817 DB12465] DB06817|Raltegravir pol;UGT1A1 DB12465|Ketanserin HTR2A common genes common pathways GO:0042493| response to drug HTR2A;UGT1A1 35642:[DB06817 DB09258] DB06817|Raltegravir pol;UGT1A1 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways GO:0007584| response to nutrient UGT1A1;SERPINC1 35643:[DB06817 DB09046] DB06817|Raltegravir pol;UGT1A1 DB09046|Metreleptin LEPR common genes common pathways 35644:[DB06817 DB05936] DB06817|Raltegravir pol;UGT1A1 DB05936|CVT-6883 ADORA2B common genes common pathways 35645:[DB06817 DB00347] DB06817|Raltegravir pol;UGT1A1 DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C19;CYP2C8;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2C19;CYP2C8;UGT1A1;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1 35646:[DB06817 DB11755] DB06817|Raltegravir pol;UGT1A1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0045471| response to ethanol CNR1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;TRPA1 GO:0007584| response to nutrient CNR1;UGT1A1 GO:0042493| response to drug UGT1A1;TRPA1 GO:0032496| response to lipopolysaccharide CNR1;CNR2;UGT1A1 GO:0010033| response to organic substance UGT1A1;TRPA1 35647:[DB06817 DB08918] DB06817|Raltegravir pol;UGT1A1 DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1;CYP2C19 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0042493| response to drug UGT1A1;SLC6A2;SLC6A4;ABCB1 GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP2D6;CYP3A4 GO:0010033| response to organic substance UGT1A1;SLC6A4 35648:[DB06817 DB01998] DB06817|Raltegravir pol;UGT1A1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways GO:0006953| acute-phase response SERPINA1;UGT1A1 35649:[DB06817 DB13168] DB06817|Raltegravir pol;UGT1A1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 35650:[DB06817 DB03066] DB06817|Raltegravir pol;UGT1A1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 35651:[DB06817 DB11892] DB06817|Raltegravir pol;UGT1A1 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 35652:[DB06817 DB06756] DB06817|Raltegravir pol;UGT1A1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;BCL2 GO:0042493| response to drug BCL2;BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE;BCL2 GO:0007584| response to nutrient UGT1A1;BCHE 35653:[DB06817 DB09332] DB06817|Raltegravir pol;UGT1A1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0017144| drug metabolic process VKORC1;UGT1A1 GO:0031100| organ regeneration UGT1A1;F7 GO:0006953| acute-phase response UGT1A1;F2 GO:0042493| response to drug UGT1A1;POR GO:0007584| response to nutrient UGT1A1;POR GO:0014070| response to organic cyclic compound F7;UGT1A1 GO:0001889| liver development PROC;UGT1A1 35654:[DB06817 DB01170] DB06817|Raltegravir pol;UGT1A1 DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug UGT1A1;SLC6A2 35655:[DB06817 DB00029] DB06817|Raltegravir pol;UGT1A1 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 35656:[DB06817 DB03023] DB06817|Raltegravir pol;UGT1A1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0042493| response to drug UGT1A1;LCK;SRC;LYN GO:0014070| response to organic cyclic compound LYN;UGT1A1 35657:[DB06817 DB11779] DB06817|Raltegravir pol;UGT1A1 DB11779|Danoprevir CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35658:[DB06817 DB06419] DB06817|Raltegravir pol;UGT1A1 DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP3A5 35659:[DB06817 DB11960] DB06817|Raltegravir pol;UGT1A1 DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 35660:[DB06817 DB09052] DB06817|Raltegravir pol;UGT1A1 DB09052|Blinatumomab CD19;CD3D common genes common pathways 35661:[DB06817 DB08834] DB06817|Raltegravir pol;UGT1A1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways 35662:[DB06817 DB03153] DB06817|Raltegravir pol;UGT1A1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 35663:[DB06817 DB12489] DB06817|Raltegravir pol;UGT1A1 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35664:[DB06817 DB00145] DB06817|Raltegravir pol;UGT1A1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0031100| organ regeneration BAAT;UGT1A1 GO:0042493| response to drug GRIN2A;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;AGXT GO:0001889| liver development BAAT;UGT1A1 GO:0045471| response to ethanol GRIN2A;UGT1A1 GO:0008152| metabolic process UGT1A1;ALAS1;GCAT;ALAS2 GO:0071361| cellular response to ethanol UGT1A1;GLRA2;GLRA1 35665:[DB06817 DB08892] DB06817|Raltegravir pol;UGT1A1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways 35666:[DB06817 DB00830] DB06817|Raltegravir pol;UGT1A1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0045471| response to ethanol SLC6A3;UGT1A1 GO:0042493| response to drug UGT1A1;SLC6A2;SLC6A3 35667:[DB06817 DB11805] DB06817|Raltegravir pol;UGT1A1 DB11805|Saracatinib CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35668:[DB06817 DB01708] DB06817|Raltegravir pol;UGT1A1 DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0008202| steroid metabolic process NR1I2;SULT2B1;SULT2A1;CYP3A4;CYP3A7;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug GRIN2A;GABRG3;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;HSD17B1 GO:0007586| digestion SULT2A1;UGT1A1 GO:0045471| response to ethanol GRIN2B;GRIN2A;GRIN1;GRIN3A;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35669:[DB06817 DB01108] DB06817|Raltegravir pol;UGT1A1 DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008152| metabolic process HSD3B2;UGT1A1;HSD3B1 GO:0071392| cellular response to estradiol stimulus ESR2;ESR1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35670:[DB06817 DB12243] DB06817|Raltegravir pol;UGT1A1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways 35671:[DB06817 DB09198] DB06817|Raltegravir pol;UGT1A1 DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes common pathways GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1;CYP2C19 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;UGT1A1;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;UGT1A1 GO:0010033| response to organic substance PPARG;CYP1A2;UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PPARG;UGT1A1 35672:[DB06817 DB05449] DB06817|Raltegravir pol;UGT1A1 DB05449|FM-VP4 ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 35673:[DB06817 DB09348] DB06817|Raltegravir pol;UGT1A1 DB09348|Propiolactone ALB common genes common pathways 35674:[DB06817 DB06733] DB06817|Raltegravir pol;UGT1A1 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 35675:[DB06817 DB02056] DB06817|Raltegravir pol;UGT1A1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0007584| response to nutrient UGT1A1;AKR1C3 GO:0008202| steroid metabolic process UGT1A1;AKR1C3 35676:[DB06817 DB01294] DB06817|Raltegravir pol;UGT1A1 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 35677:[DB06817 DB04665] DB06817|Raltegravir pol;UGT1A1 DB04665|Coumarin CYP2A6;CYP2C9 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2A6;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2A6;UGT1A1 35678:[DB06817 DB04821] DB06817|Raltegravir pol;UGT1A1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;MPO;MAOB GO:0006953| acute-phase response UGT1A1;ORM1 GO:0042493| response to drug SLC6A3;MAOB;SLC6A2;UGT1A1;SLC6A4 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0045471| response to ethanol MAOB;SLC6A3;UGT1A1 35679:[DB06817 DB01022] DB06817|Raltegravir pol;UGT1A1 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 35680:[DB06817 DB04576] DB06817|Raltegravir pol;UGT1A1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 35681:[DB06817 DB02337] DB06817|Raltegravir pol;UGT1A1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 35682:[DB06817 DB14641] DB06817|Raltegravir pol;UGT1A1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1;ESR2 35683:[DB06817 DB13998] DB06817|Raltegravir pol;UGT1A1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0001889| liver development UGT1A1;PROC GO:0010033| response to organic substance CALR;UGT1A1 GO:0006953| acute-phase response UGT1A1;F2 GO:0042493| response to drug UGT1A1;CALR 35684:[DB06817 DB04877] DB06817|Raltegravir pol;UGT1A1 DB04877|Voacamine ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 35685:[DB06817 DB00611] DB06817|Raltegravir pol;UGT1A1 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 35686:[DB06817 DB02105] DB06817|Raltegravir pol;UGT1A1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;COMT GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0042493| response to drug COMT;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;COMT 35687:[DB06817 DB09072] DB06817|Raltegravir pol;UGT1A1 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways GO:0008152| metabolic process UGT1A1;ALDH5A1 35688:[DB06817 DB03203] DB06817|Raltegravir pol;UGT1A1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 35689:[DB06817 DB13988] DB06817|Raltegravir pol;UGT1A1 DB13988|SB-269970 HTR7 common genes common pathways 35690:[DB06817 DB01049] DB06817|Raltegravir pol;UGT1A1 DB01049|Ergoloid mesylate DRD1;DRD5;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;CYP3A4 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0045471| response to ethanol DRD3;HTR1B;HTR3A;DRD2;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug DRD3;HTR1B;HTR2C;UGT1A1;HTR2B;DRD2;ADRA1A;HTR2A;DRD1 35691:[DB06817 DB11726] DB06817|Raltegravir pol;UGT1A1 DB11726|Encenicline CHRNA7 common genes common pathways 35692:[DB06817 DB06770] DB06817|Raltegravir pol;UGT1A1 DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;UGT1A1;CYP1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0008152| metabolic process UGT1A1;ALDH2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0042493| response to drug CYP1A2;UGT1A1;CYP1A1;CYP2E1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;CYP1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2D6;CYP2C8;UGT1A1;CYP2E1;CYP1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2E1;CYP1A1;CYP1A2;CYP2D6 35693:[DB06817 DB00779] DB06817|Raltegravir pol;UGT1A1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways 35694:[DB06817 DB01016] DB06817|Raltegravir pol;UGT1A1 DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes common pathways GO:0042493| response to drug KCNJ11;ABCC8;ABCC9;UGT1A1;ABCC1;ABCG2;ABCA1;ABCC2;ABCB1;CPT1A GO:0032496| response to lipopolysaccharide KCNJ8;ABCC2;ABCC8;UGT1A1 GO:0007586| digestion SLC15A1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;ABCA1;CYP2C9;CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2C9 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0014070| response to organic cyclic compound CPT1A;UGT1A1 GO:0007584| response to nutrient ABCA1;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 35695:[DB06817 DB05928] DB06817|Raltegravir pol;UGT1A1 DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP1A1;UGT2B7;CYP3A4;NR1I2;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP1A1;CYP3A4;UGT1A3;CYP1A2 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:1904224| UGT1A3;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A1;UGT1A1;ABCG2;CYP1A2;ABCB1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A3 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;UGT1A1;CYP2C19 GO:0008152| metabolic process UGT1A3;UGT2B7;UGT1A1 GO:0052695| cellular glucuronidation UGT1A3;UGT2B7;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 35696:[DB06817 DB01562] DB06817|Raltegravir pol;UGT1A1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;UGT1A1 35697:[DB06817 DB13952] DB06817|Raltegravir pol;UGT1A1 DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes UGT1A1 common pathways GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;CYP1A1;UGT1A1;CYP2C19 GO:0051552| flavone metabolic process UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;CYP1A2 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0042493| response to drug ABCG2;UGT1A1;BECN1;CYP1A1;ABCB1;CYP1A2 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion FABP2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;CYP1A2 GO:1904224| UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1;CYP1A2 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;UGT1A1;CYP1A1;CYP3A4;CYP1A2;CYP2C9 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A7;CYP1A1;CYP3A5;UGT1A1;CYP2C8;CYP2C19;CYP1A2;NR1I2;CYP2C9;CYP3A4;CYP1B1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR2;GPER1;ESR1 35698:[DB06817 DB00016] DB06817|Raltegravir pol;UGT1A1 DB00016|Erythropoietin EPOR common genes common pathways 35699:[DB06817 DB06704] DB06817|Raltegravir pol;UGT1A1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;UGT1A1 35700:[DB06817 DB00142] DB06817|Raltegravir pol;UGT1A1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0031100| organ regeneration UGT1A1;FPGS GO:0042493| response to drug ABAT;GRIN2A;GAD1;PFAS;SLC1A2;SLC1A3;UGT1A1;GAD2;GCLM GO:0007584| response to nutrient GCLC;GCLM;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;TAT GO:0032870| cellular response to hormone stimulus ASNS;UGT1A1 GO:0051384| response to glucocorticoid stimulus GOT1;UGT1A1;TAT GO:0008152| metabolic process BCAT2;FOLH1;UGT1A1;ALDH18A1;EPRS;FTCD;BCAT1;AASS GO:0045471| response to ethanol GOT2;ABAT;GRIN2B;GRIN2A;GRIN1;UGT1A1;GRIN3A GO:0001889| liver development FPGS;ASNS;UGT1A1 35701:[DB06817 DB00872] DB06817|Raltegravir pol;UGT1A1 DB00872|Conivaptan AVPR1A;AVPR2;CYP3A4 common genes common pathways GO:0010033| response to organic substance AVPR1A;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032870| cellular response to hormone stimulus AVPR1A;AVPR2;UGT1A1 35702:[DB06817 DB00508] DB06817|Raltegravir pol;UGT1A1 DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0045471| response to ethanol UGT1A1;DRD2 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0042493| response to drug DRD2;DRD1;UGT1A1;HTR2B;BCHE;ABCB1 35703:[DB06817 DB13173] DB06817|Raltegravir pol;UGT1A1 DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0001889| liver development UGT1A1;IGF2R GO:0031100| organ regeneration UGT1A1;IGF2R 35704:[DB06817 DB06680] DB06817|Raltegravir pol;UGT1A1 DB06680|Asoprisnil PGR common genes common pathways 35705:[DB06817 DB00486] DB06817|Raltegravir pol;UGT1A1 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2E1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2C8;UGT1A1;CYP2E1 GO:0042493| response to drug UGT1A1;CYP2E1 GO:0032496| response to lipopolysaccharide CNR1;UGT1A1;CNR2 GO:0007584| response to nutrient UGT1A1;CNR1 GO:0045471| response to ethanol CNR1;UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 35706:[DB06817 DB05120] DB06817|Raltegravir pol;UGT1A1 DB05120|AT1391 INSR common genes common pathways 35707:[DB06817 DB09207] DB06817|Raltegravir pol;UGT1A1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0045471| response to ethanol UGT1A1;DRD2;DRD3 GO:0042493| response to drug DRD3;UGT1A1;DRD2 35708:[DB06817 DB08871] DB06817|Raltegravir pol;UGT1A1 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0042493| response to drug UGT1A1;BCL2 GO:0048545| response to steroid hormone stimulus UGT1A1;BCL2 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2 35709:[DB06817 DB05996] DB06817|Raltegravir pol;UGT1A1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways 35710:[DB06817 DB05915] DB06817|Raltegravir pol;UGT1A1 DB05915|MYO-029 MSTN common genes common pathways GO:0051384| response to glucocorticoid stimulus MSTN;UGT1A1 GO:0045471| response to ethanol UGT1A1;MSTN 35711:[DB06817 DB09223] DB06817|Raltegravir pol;UGT1A1 DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0045471| response to ethanol DRD3;UGT1A1;DRD2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug DRD3;UGT1A1;DRD2;HTR2A GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 35712:[DB06817 DB09285] DB06817|Raltegravir pol;UGT1A1 DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0042493| response to drug TBXA2R;UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide TBXA2R;PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0045471| response to ethanol TBXA2R;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0007584| response to nutrient TBXA2R;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 35713:[DB06817 DB03048] DB06817|Raltegravir pol;UGT1A1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways 35714:[DB06817 DB01106] DB06817|Raltegravir pol;UGT1A1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways 35715:[DB06817 DB01210] DB06817|Raltegravir pol;UGT1A1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 35716:[DB06817 DB06217] DB06817|Raltegravir pol;UGT1A1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0010033| response to organic substance KCNA5;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 35717:[DB06817 DB07960] DB06817|Raltegravir pol;UGT1A1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways GO:0008152| metabolic process UGT1A1;NEU2 35718:[DB06817 DB02266] DB06817|Raltegravir pol;UGT1A1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0042493| response to drug UGT1A1;PTGS2;PPARG GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042594| response to starvation UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PTGS2;PPARG GO:0008202| steroid metabolic process AKR1C3;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0014070| response to organic cyclic compound PPARG;PTGS2;UGT1A1 GO:0007584| response to nutrient AKR1C3;PPARG;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 35719:[DB06817 DB02377] DB06817|Raltegravir pol;UGT1A1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0008152| metabolic process GCH1;UGT1A1 GO:0032496| response to lipopolysaccharide GCH1;UGT1A1 GO:0042493| response to drug UGT1A1;PNP 35720:[DB06817 DB12305] DB06817|Raltegravir pol;UGT1A1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0045471| response to ethanol UGT1A1;SLC6A3 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0042493| response to drug SLC6A3;SLC6A2;UGT1A1;SLC6A4 35721:[DB06817 DB01209] DB06817|Raltegravir pol;UGT1A1 DB01209|Dezocine OPRM1;OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 35722:[DB06817 DB08992] DB06817|Raltegravir pol;UGT1A1 DB08992|Eperisone CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35723:[DB06817 DB12752] DB06817|Raltegravir pol;UGT1A1 DB12752|Bucindolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 35724:[DB06817 DB11251] DB06817|Raltegravir pol;UGT1A1 DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0017144| drug metabolic process CYP4F2;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;VLDLR;UGT1A1;APOBR;LDLR GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0007584| response to nutrient TTPA;UGT1A1 35725:[DB06817 DB04153] DB06817|Raltegravir pol;UGT1A1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0032496| response to lipopolysaccharide ADH5;UGT1A1 35726:[DB06817 DB09330] DB06817|Raltegravir pol;UGT1A1 DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;ABCG2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0071392| cellular response to estradiol stimulus UGT1A1;EGFR GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0001889| liver development EGFR;UGT1A1 GO:0014070| response to organic cyclic compound EGFR;UGT1A1;CYP1A2 35727:[DB06817 DB00051] DB06817|Raltegravir pol;UGT1A1 DB00051|Adalimumab TNF common genes common pathways GO:0010033| response to organic substance TNF;UGT1A1 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 35728:[DB06817 DB05740] DB06817|Raltegravir pol;UGT1A1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0045471| response to ethanol UGT1A1;CHRNB2 35729:[DB06817 DB03756] DB06817|Raltegravir pol;UGT1A1 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0007584| response to nutrient PPARG;UGT1A1 GO:0014070| response to organic cyclic compound SREBF1;UGT1A1;PPARG GO:0042493| response to drug UGT1A1;SREBF1;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;SREBF1;UGT1A1 35730:[DB06817 DB06362] DB06817|Raltegravir pol;UGT1A1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 35731:[DB06817 DB03052] DB06817|Raltegravir pol;UGT1A1 DB03052|Dazoxiben TBXAS1 common genes common pathways 35732:[DB06817 DB01024] DB06817|Raltegravir pol;UGT1A1 DB01024|Mycophenolic acid IMPDH1;IMPDH2;UGT1A1;UGT1A9;UGT2B7;UGT1A7;UGT1A6 common genes UGT1A1 common pathways GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A7;UGT1A9;UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0051552| flavone metabolic process UGT1A7;UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A7;UGT1A9;UGT2B7;UGT1A1;UGT1A6 GO:0071361| cellular response to ethanol UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A6;UGT1A1;UGT1A9;UGT1A7 GO:0043086| negative regulation of catalytic activity UGT1A7;UGT1A1 GO:0052695| cellular glucuronidation UGT1A7;UGT1A9;UGT2B7;UGT1A1;UGT1A6 GO:0006789| bilirubin conjugation UGT1A1 GO:0008202| steroid metabolic process UGT2B7;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A6;UGT1A9;UGT1A7 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A7;UGT1A1;UGT1A6 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A6;UGT1A7;UGT1A9 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A6;UGT1A9;UGT1A7 GO:0010033| response to organic substance UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:1904224| UGT1A9;UGT1A7;UGT1A1;UGT1A6 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0042493| response to drug UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 35733:[DB06817 DB00473] DB06817|Raltegravir pol;UGT1A1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 35734:[DB06817 DB01046] DB06817|Raltegravir pol;UGT1A1 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CBR1 35735:[DB06817 DB03147] DB06817|Raltegravir pol;UGT1A1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;AIFM1 GO:0008202| steroid metabolic process UGT1A1;CYB5R3;CYB5R1;FDXR GO:0032496| response to lipopolysaccharide MAOB;UGT1A1 GO:0042493| response to drug UGT1A1;MAOB;POR GO:0007584| response to nutrient UGT1A1;NQO1;POR GO:0014070| response to organic cyclic compound NQO1;UGT1A1 GO:0008152| metabolic process ACADS;ACOX1;IVD;UGT1A1;ACAD8;GCDH;ACADM GO:0001889| liver development GFER;UGT1A1 GO:0045471| response to ethanol UGT1A1;MAOB;NQO1 GO:0043086| negative regulation of catalytic activity NQO1;UGT1A1 35736:[DB06817 DB00235] DB06817|Raltegravir pol;UGT1A1 DB00235|Milrinone PDE3A common genes common pathways GO:0042493| response to drug UGT1A1;PDE3A 35737:[DB06817 DB05015] DB06817|Raltegravir pol;UGT1A1 DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0010033| response to organic substance CYP1A2;HDAC6;UGT1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP1A2;UGT1A1;CYP2C8 GO:0042493| response to drug HDAC2;UGT1A1;HDAC1;HDAC5;ABCB1;CYP1A2;HDAC4 GO:0032496| response to lipopolysaccharide UGT1A1;HDAC2;HDAC1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 35738:[DB06817 DB01396] DB06817|Raltegravir pol;UGT1A1 DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP11A1;CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug ATP1A1;UGT1A1;ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35739:[DB06817 DB06717] DB06817|Raltegravir pol;UGT1A1 DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP3A4 35740:[DB06817 DB03619] DB06817|Raltegravir pol;UGT1A1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0008152| metabolic process UGT1A1;GSTP1 GO:0045471| response to ethanol UGT1A1;GSTP1 35741:[DB06817 DB06374] DB06817|Raltegravir pol;UGT1A1 DB06374|Elacestrant ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 35742:[DB06817 DB01407] DB06817|Raltegravir pol;UGT1A1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0042493| response to drug CYP1A1;UGT1A1 GO:0017144| drug metabolic process CYP1A1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A1 GO:0010033| response to organic substance CYP1A1;TNF;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 35743:[DB06817 DB01439] DB06817|Raltegravir pol;UGT1A1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 35744:[DB06817 DB00072] DB06817|Raltegravir pol;UGT1A1 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0001889| liver development UGT1A1;EGFR GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1 35745:[DB06817 DB01411] DB06817|Raltegravir pol;UGT1A1 DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0017144| drug metabolic process CYP2C9;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT1A1 GO:0010033| response to organic substance TNF;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0042493| response to drug UGT1A1;ABCC2 35746:[DB06817 DB00041] DB06817|Raltegravir pol;UGT1A1 DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0008152| metabolic process UGT1A1;PLA2G4A GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 35747:[DB06817 DB13146] DB06817|Raltegravir pol;UGT1A1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0045471| response to ethanol GRIN2B;GRIN2A;GRIN1;UGT1A1;GRIN3A GO:0010033| response to organic substance ABCC4;UGT1A1 GO:0042493| response to drug UGT1A1;ABCC4;GRIN2A;ABCB1 35748:[DB06817 DB09555] DB06817|Raltegravir pol;UGT1A1 DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1 35749:[DB06817 DB01429] DB06817|Raltegravir pol;UGT1A1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 35750:[DB06817 DB09338] DB06817|Raltegravir pol;UGT1A1 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0008152| metabolic process UGT1A1;ALPL GO:0051384| response to glucocorticoid stimulus ALPL;UGT1A1 GO:0032496| response to lipopolysaccharide ALPL;PCK1;UGT1A1 GO:0042493| response to drug AQP1;UGT1A1 35751:[DB06817 DB09418] DB06817|Raltegravir pol;UGT1A1 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways 35752:[DB06817 DB05254] DB06817|Raltegravir pol;UGT1A1 DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways 35753:[DB06817 DB01127] DB06817|Raltegravir pol;UGT1A1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;NR1I2;UGT1A1;CYP2E1 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP3A4 GO:0045471| response to ethanol CYP2E1;UGT1A1 35754:[DB06817 DB12952] DB06817|Raltegravir pol;UGT1A1 DB12952|Methylprednisone CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35755:[DB06817 DB02552] DB06817|Raltegravir pol;UGT1A1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;FDPS 35756:[DB06817 DB08699] DB06817|Raltegravir pol;UGT1A1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways 35757:[DB06817 DB00380] DB06817|Raltegravir pol;UGT1A1 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways 35758:[DB06817 DB03800] DB06817|Raltegravir pol;UGT1A1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes pol common pathways GO:0045471| response to ethanol UGT1A1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0042493| response to drug UGT1A1;TYMS 35759:[DB06817 DB00195] DB06817|Raltegravir pol;UGT1A1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP2D6 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 35760:[DB06817 DB04789] DB06817|Raltegravir pol;UGT1A1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0042493| response to drug ABCC2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 35761:[DB06817 DB09288] DB06817|Raltegravir pol;UGT1A1 DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes UGT1A1 common pathways GO:0008152| metabolic process NAT2;UGT1A9;UGT1A1;UGT2B15;UGT1A6;UGT1A10 GO:0071361| cellular response to ethanol UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;UGT1A1;CYP2E1 GO:0051552| flavone metabolic process UGT1A9;UGT1A10;UGT1A1 GO:0045471| response to ethanol CNR1;UGT1A1;CYP2E1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A6;UGT1A1;UGT1A10;UGT1A9 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A9;UGT1A10;UGT1A6;UGT2B15;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1;BCHE GO:0042167| heme catabolic process UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE;CNR1 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;CYP1A2 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion SULT2A1;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1;CYP1A2;CNR1 GO:1904224| UGT1A6;UGT1A1;UGT1A10;UGT1A9 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process SULT1E1;UGT1A1;SULT1A1 GO:0006953| acute-phase response UGT1A1 GO:0042493| response to drug BCHE;CYP1A2;CYP2E1;UGT1A1;PTGS2 GO:0031100| organ regeneration UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A6;UGT1A1;CYP2E1;UGT1A10;CYP3A4;UGT1A9;CYP1A2;CYP2D6;CYP2C9 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1;UGT2B15;SULT1A1;SULT1A3;SULT1E1;CYP2C9;CYP2D6;CYP1A2;CYP3A4;SULT2A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0010033| response to organic substance CYP1A2;PTGS2;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A10;UGT1A1;UGT1A6;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A6;UGT1A10;UGT1A9 GO:0052697| xenobiotic glucuronidation UGT1A10;UGT1A6;UGT1A1;UGT1A9 35762:[DB06817 DB01363] DB06817|Raltegravir pol;UGT1A1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0045471| response to ethanol MAOB;SLC6A3;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0042493| response to drug SLC6A4;SLC6A2;UGT1A1;SLC6A3;MAOB GO:0032496| response to lipopolysaccharide MAOB;UGT1A1 35763:[DB06817 DB00499] DB06817|Raltegravir pol;UGT1A1 DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP1A1;CYP2C19;UGT1A1;NR1I2;CYP1A2;CYP1B1;CYP3A4 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP1A1;CYP3A4;CYP1A2 GO:0010033| response to organic substance CYP1A2;CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;UGT1A1 GO:0042493| response to drug CYP1A2;CYP1A1;UGT1A1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;UGT1A1;CYP1A1 GO:0001889| liver development CYP1A1;UGT1A1 35764:[DB06817 DB14540] DB06817|Raltegravir pol;UGT1A1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0008152| metabolic process UGT1A1;HSD3B1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;CYP11B2;CYP11B1 GO:0051384| response to glucocorticoid stimulus UGT1A1;HSD11B2;ANXA1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1;ANXA1 GO:0042493| response to drug UGT1A1;ABCG2;ANXA1;HSD11B2;ABCB1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0048545| response to steroid hormone stimulus HSD11B2;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP11B2;CYP3A5;CYP11B1;CYP3A7 35765:[DB06817 DB01369] DB06817|Raltegravir pol;UGT1A1 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35766:[DB06817 DB00474] DB06817|Raltegravir pol;UGT1A1 DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP2C19;UGT1A1 GO:0017144| drug metabolic process CYP2C19;UGT1A1 35767:[DB06817 DB13953] DB06817|Raltegravir pol;UGT1A1 DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes UGT1A1 common pathways GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP2C19;CYP1A2;CYP3A4 GO:0001889| liver development UGT1A1;CYP1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP3A5;CYP1A1;CYP3A7;CYP1B1;CYP3A4;NR1I2;CYP2C9;CYP1A2 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;GPER1;ESR1;ESR2 GO:0031100| organ regeneration UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP1A2;UGT1A1;CYP2C19;CYP2C8;CYP1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1;CYP1A2 GO:1904224| UGT1A1 GO:0007586| digestion UGT1A1;FABP2 GO:0042594| response to starvation UGT1A1 GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;BECN1;ABCG2;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 35768:[DB06817 DB09291] DB06817|Raltegravir pol;UGT1A1 DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;ABCG2 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 35769:[DB06817 DB01351] DB06817|Raltegravir pol;UGT1A1 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2A6;UGT1A1 GO:0017144| drug metabolic process CYP2A6;UGT1A1 35770:[DB06817 DB01380] DB06817|Raltegravir pol;UGT1A1 DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35771:[DB06817 DB00435] DB06817|Raltegravir pol;UGT1A1 DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0008152| metabolic process UGT1A1;ALDH2 GO:0008202| steroid metabolic process CYP1A2;CYP2B6;CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP2B6;CYP1A2;CYP3A4;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;IDO1 GO:0042493| response to drug CYP1A2;UGT1A1 35772:[DB06817 DB13872] DB06817|Raltegravir pol;UGT1A1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways 35773:[DB06817 DB14503] DB06817|Raltegravir pol;UGT1A1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0007584| response to nutrient UGT1A1;SLC34A1 GO:0042493| response to drug SLC34A1;UGT1A1 35774:[DB06817 DB06190] DB06817|Raltegravir pol;UGT1A1 DB06190|Solabegron ADRB3 common genes common pathways 35775:[DB06817 DB06787] DB06817|Raltegravir pol;UGT1A1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 35776:[DB06817 DB06652] DB06817|Raltegravir pol;UGT1A1 DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A5;UGT1A1;CYP2C9;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35777:[DB06817 DB06412] DB06817|Raltegravir pol;UGT1A1 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0001889| liver development SRD5A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0014070| response to organic cyclic compound SRD5A1;UGT1A1 GO:0042493| response to drug UGT1A1;SRD5A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;SRD5A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A5;CYP3A7;SRD5A1;CYP3A4;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 35778:[DB06817 DB01228] DB06817|Raltegravir pol;UGT1A1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 35779:[DB06817 DB08901] DB06817|Raltegravir pol;UGT1A1 DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0010033| response to organic substance UGT1A1;TEK GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1;CYP3A5 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0031100| organ regeneration UGT1A1;FLT3 GO:0042493| response to drug LCK;ABCG2;UGT1A1;RET;SRC;ABCB1;LYN GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0032496| response to lipopolysaccharide FGFR2;BCR;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;LYN GO:0045471| response to ethanol FGFR2;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 35780:[DB06817 DB11581] DB06817|Raltegravir pol;UGT1A1 DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;BCL2;ABCG2;UGT1A1 GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2 35781:[DB06817 DB06241] DB06817|Raltegravir pol;UGT1A1 DB06241|Clenoliximab CD4 common genes common pathways 35782:[DB06817 DB01138] DB06817|Raltegravir pol;UGT1A1 DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0010033| response to organic substance UGT1A1;ABCC4 GO:0008202| steroid metabolic process CYP2B6;NR1I2;CYP2C9;CYP3A4;CYP2C8;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2B6;CYP2C9 GO:0042493| response to drug SLC22A12;ABCC1;UGT1A1;ABCC6;ABCC2;ABCC4 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0007586| digestion UGT1A1;FABP2 35783:[DB06817 DB01252] DB06817|Raltegravir pol;UGT1A1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0010033| response to organic substance PPARG;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A3;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0017144| drug metabolic process UGT1A1;UGT1A3 GO:0031100| organ regeneration UGT1A1;PPARG GO:0008202| steroid metabolic process UGT1A1;UGT2B7 GO:0042493| response to drug PPARG;ABCC8;UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:1904224| UGT1A3;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC8 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0052695| cellular glucuronidation UGT2B7;UGT1A1;UGT1A3 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A3 GO:0008152| metabolic process UGT1A3;UGT1A1;UGT2B7 35784:[DB06817 DB00814] DB06817|Raltegravir pol;UGT1A1 DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways GO:0014070| response to organic cyclic compound ABCC4;PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0010033| response to organic substance PTGS2;UGT1A1;ABCC4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT1A1;CYP2C8 GO:0042493| response to drug PTGS2;UGT1A1;ABCC4 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 35785:[DB06817 DB06262] DB06817|Raltegravir pol;UGT1A1 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0008152| metabolic process UGT1A1;PAH GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug ADRA1A;UGT1A1;SLC6A2 35786:[DB06817 DB05303] DB06817|Raltegravir pol;UGT1A1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0010033| response to organic substance UGT1A1;TNF GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 35787:[DB06817 DB00002] DB06817|Raltegravir pol;UGT1A1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;EGFR GO:0001889| liver development UGT1A1;EGFR GO:0014070| response to organic cyclic compound EGFR;UGT1A1 35788:[DB06817 DB09146] DB06817|Raltegravir pol;UGT1A1 DB09146|Iron saccharate HBA1;TF common genes common pathways 35789:[DB06817 DB09449] DB06817|Raltegravir pol;UGT1A1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0007584| response to nutrient SLC34A1;UGT1A1 GO:0042493| response to drug SLC34A1;UGT1A1 35790:[DB06817 DB00533] DB06817|Raltegravir pol;UGT1A1 DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4;CYP1A2;CYP2C9 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9;CYP1A2;CYP3A4 GO:0010033| response to organic substance UGT1A1;PTGS2;ABCC4;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1;ABCC4;CYP1A2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound ABCC4;CYP1A2;PTGS2;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 35791:[DB06817 DB00083] DB06817|Raltegravir pol;UGT1A1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 35792:[DB06817 DB13269] DB06817|Raltegravir pol;UGT1A1 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0042493| response to drug UGT1A1;SCN11A 35793:[DB06817 DB06772] DB06817|Raltegravir pol;UGT1A1 DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCG2;UGT1A1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1;CYP3A5 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35794:[DB06817 DB13775] DB06817|Raltegravir pol;UGT1A1 DB13775|Tertatolol CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 35795:[DB06817 DB09200] DB06817|Raltegravir pol;UGT1A1 DB09200|Rivoglitazone CYP3A4;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35796:[DB06817 DB13950] DB06817|Raltegravir pol;UGT1A1 DB13950|WIN 55212-2 CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35797:[DB06817 DB06370] DB06817|Raltegravir pol;UGT1A1 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0042493| response to drug CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP3A4;CYP2E1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1;CYP3A4;CYP2C9;CYP2D6 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP2D6;CYP3A4 GO:0045471| response to ethanol UGT1A1;CYP2E1 35798:[DB06817 DB13866] DB06817|Raltegravir pol;UGT1A1 DB13866|Etynodiol CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35799:[DB06817 DB11348] DB06817|Raltegravir pol;UGT1A1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0010033| response to organic substance UGT1A1;CALR;CASQ1 GO:0032496| response to lipopolysaccharide UGT1A1;SPARC GO:0042493| response to drug SLC34A1;UGT1A1;CALR;SLC8A1 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;SPARC;S100B GO:0007584| response to nutrient SLC34A1;UGT1A1;SLC8A1 GO:0014070| response to organic cyclic compound UGT1A1;CASR GO:0045471| response to ethanol UGT1A1;SPARC GO:0001889| liver development RGN;UGT1A1 35800:[DB06817 DB12191] DB06817|Raltegravir pol;UGT1A1 DB12191|Obatoclax BCL2 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2 GO:0048545| response to steroid hormone stimulus UGT1A1;BCL2 GO:0042493| response to drug UGT1A1;BCL2 35801:[DB06817 DB08807] DB06817|Raltegravir pol;UGT1A1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0042493| response to drug UGT1A1;HTR1B GO:0045471| response to ethanol UGT1A1;HTR1B GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 35802:[DB06817 DB11130] DB06817|Raltegravir pol;UGT1A1 DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0042493| response to drug B2M;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 35803:[DB06817 DB06734] DB06817|Raltegravir pol;UGT1A1 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 35804:[DB06817 DB00589] DB06817|Raltegravir pol;UGT1A1 DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0042493| response to drug DRD3;HTR1B;HTR2C;UGT1A1;HTR2B;HTR2A;DRD1;DRD2 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0045471| response to ethanol DRD2;UGT1A1;DRD3;HTR1B GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 35805:[DB06817 DB09502] DB06817|Raltegravir pol;UGT1A1 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0045471| response to ethanol SLC2A4;UGT1A1 GO:0008152| metabolic process HK1;UGT1A1 35806:[DB06817 DB05505] DB06817|Raltegravir pol;UGT1A1 DB05505|NM-702 TBXAS1 common genes common pathways 35807:[DB06817 DB01200] DB06817|Raltegravir pol;UGT1A1 DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0045471| response to ethanol UGT1A1;DRD2;DRD3;HTR1B GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug DRD1;HTR2A;DRD2;ADRA1A;HTR2B;UGT1A1;HTR2C;ABCB1;HTR1B;DRD3 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35808:[DB06817 DB01240] DB06817|Raltegravir pol;UGT1A1 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;PTGIR 35809:[DB06817 DB11607] DB06817|Raltegravir pol;UGT1A1 DB11607|Efmoroctocog alfa VWF common genes common pathways 35810:[DB06817 DB05039] DB06817|Raltegravir pol;UGT1A1 DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes UGT1A1 common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 35811:[DB06817 DB04825] DB06817|Raltegravir pol;UGT1A1 DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35812:[DB06817 DB04964] DB06817|Raltegravir pol;UGT1A1 DB04964|Oregovomab MUC16 common genes common pathways 35813:[DB06817 DB05476] DB06817|Raltegravir pol;UGT1A1 DB05476|WX-UK1 PLAUR common genes common pathways 35814:[DB06817 DB09029] DB06817|Raltegravir pol;UGT1A1 DB09029|Secukinumab IL17A common genes common pathways 35815:[DB06817 DB00097] DB06817|Raltegravir pol;UGT1A1 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways 35816:[DB06817 DB00210] DB06817|Raltegravir pol;UGT1A1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0001889| liver development UGT1A1;RARA GO:0045471| response to ethanol RARA;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 35817:[DB06817 DB01155] DB06817|Raltegravir pol;UGT1A1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 35818:[DB06817 DB05431] DB06817|Raltegravir pol;UGT1A1 DB05431|MLN-977 ALOX5 common genes common pathways 35819:[DB06817 DB02998] DB06817|Raltegravir pol;UGT1A1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 35820:[DB06817 DB14635] DB06817|Raltegravir pol;UGT1A1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP1A2;CYP2D6;CYP2C9;CYP2B6;CYP3A4 GO:0031100| organ regeneration PPARG;GSTP1;UGT1A1 GO:0017144| drug metabolic process CYP2D6;CYP2B6;CYP2C9;CYP1A2;CYP3A4;UGT1A1;CBR1 GO:0010033| response to organic substance UGT1A1;PPARG;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug CYP1A2;ABCB1;PPARG;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2;CYP2D6 GO:0045471| response to ethanol UGT1A1;GSTP1 GO:0008152| metabolic process GSTP1;UGT1A1;GSTA1;GSTM1 35821:[DB06817 DB11712] DB06817|Raltegravir pol;UGT1A1 DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35822:[DB06817 DB02813] DB06817|Raltegravir pol;UGT1A1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways GO:0008152| metabolic process HEXB;UGT1A1 35823:[DB06817 DB12334] DB06817|Raltegravir pol;UGT1A1 DB12334|Milataxel TUBB1;TUBB common genes common pathways 35824:[DB06817 DB07462] DB06817|Raltegravir pol;UGT1A1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;COMT GO:0042493| response to drug COMT;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0014070| response to organic cyclic compound COMT;UGT1A1 35825:[DB06817 DB09303] DB06817|Raltegravir pol;UGT1A1 DB09303|Evolocumab PCSK9 common genes common pathways GO:0001889| liver development PCSK9;UGT1A1 GO:0008202| steroid metabolic process PCSK9;UGT1A1 35826:[DB06817 DB06212] DB06817|Raltegravir pol;UGT1A1 DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways GO:0010033| response to organic substance AVPR1A;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug UGT1A1;ABCB1 GO:0032870| cellular response to hormone stimulus AVPR2;AVPR1A;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35827:[DB06817 DB05668] DB06817|Raltegravir pol;UGT1A1 DB05668|Palifosfamide DNMT1 common genes common pathways 35828:[DB06817 DB03403] DB06817|Raltegravir pol;UGT1A1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways GO:0008152| metabolic process UGT1A1;UCK2 35829:[DB06817 DB00685] DB06817|Raltegravir pol;UGT1A1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 35830:[DB06817 DB06237] DB06817|Raltegravir pol;UGT1A1 DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0008152| metabolic process UGT1A1;PDE5A GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35831:[DB06817 DB04074] DB06817|Raltegravir pol;UGT1A1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0008152| metabolic process BCAT2;UGT1A1 35832:[DB06817 DB01102] DB06817|Raltegravir pol;UGT1A1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways 35833:[DB06817 DB04843] DB06817|Raltegravir pol;UGT1A1 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 35834:[DB06817 DB11703] DB06817|Raltegravir pol;UGT1A1 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP3A5;CYP3A7 GO:0010033| response to organic substance BTK;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35835:[DB06817 DB00655] DB06817|Raltegravir pol;UGT1A1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1;ESR2 GO:0008202| steroid metabolic process CYP1A2;CYP2C9;CYP2B6;CYP3A4;CYP1B1;CYP2E1;CYP3A5;CYP1A1;UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP2B6;CYP2C9;CYP3A4;CYP2E1;CYP1A1;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;UGT1A1 GO:0042493| response to drug ABCG2;UGT1A1;CYP1A1;CYP2E1;ABCB1;CYP1A2 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP1A1;CYP3A4;CYP1A2 35836:[DB06817 DB05087] DB06817|Raltegravir pol;UGT1A1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways 35837:[DB06817 DB04840] DB06817|Raltegravir pol;UGT1A1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0008202| steroid metabolic process CYP2D6;CYP1A1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP2D6 GO:0042493| response to drug ABCB1;CYP1A1;SLC6A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP2D6 GO:0001889| liver development CYP1A1;UGT1A1 35838:[DB06817 DB00886] DB06817|Raltegravir pol;UGT1A1 DB00886|Omapatrilat ACE;MME common genes common pathways 35839:[DB06817 DB14642] DB06817|Raltegravir pol;UGT1A1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0010033| response to organic substance AVPR1A;UGT1A1 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1 GO:0042493| response to drug UGT1A1;ABCC2 GO:0032870| cellular response to hormone stimulus AVPR1A;ABCC2;AVPR2;AVPR1B;UGT1A1 35840:[DB06817 DB06536] DB06817|Raltegravir pol;UGT1A1 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0042594| response to starvation PPARG;UGT1A1 GO:0042493| response to drug UGT1A1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0010033| response to organic substance PPARG;UGT1A1 35841:[DB06817 DB01219] DB06817|Raltegravir pol;UGT1A1 DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 35842:[DB06817 DB09166] DB06817|Raltegravir pol;UGT1A1 DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0032496| response to lipopolysaccharide UGT1A1;PTAFR GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 35843:[DB06817 DB12945] DB06817|Raltegravir pol;UGT1A1 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 35844:[DB06817 DB04889] DB06817|Raltegravir pol;UGT1A1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0032496| response to lipopolysaccharide MAOB;UGT1A1 GO:0042493| response to drug SLC6A4;SLC6A2;UGT1A1;MAOB;DRD2 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0045471| response to ethanol UGT1A1;MAOB;DRD2 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 35845:[DB06817 DB00782] DB06817|Raltegravir pol;UGT1A1 DB00782|Propantheline CHRM1 common genes common pathways 35846:[DB06817 DB14508] DB06817|Raltegravir pol;UGT1A1 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways 35847:[DB06817 DB04872] DB06817|Raltegravir pol;UGT1A1 DB04872|Osanetant TACR3 common genes common pathways 35848:[DB06817 DB05434] DB06817|Raltegravir pol;UGT1A1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0031100| organ regeneration UGT1A1;HGF GO:0001889| liver development HGF;UGT1A1 35849:[DB06817 DB01008] DB06817|Raltegravir pol;UGT1A1 DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol GSTP1;UGT1A1 GO:0008152| metabolic process GSTP1;GSTA2;GSTA1;UGT1A1;GSTM1 GO:0032496| response to lipopolysaccharide MGST2;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35850:[DB06817 DB06211] DB06817|Raltegravir pol;UGT1A1 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways 35851:[DB06817 DB00517] DB06817|Raltegravir pol;UGT1A1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 35852:[DB06817 DB08838] DB06817|Raltegravir pol;UGT1A1 DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol UGT1A1;GRIN1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 35853:[DB06817 DB00131] DB06817|Raltegravir pol;UGT1A1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0042493| response to drug UGT1A1;CREB1;ADCY1;ACSL1 GO:0010033| response to organic substance AMPD1;ACSL1;UGT1A1;CREB1 GO:0008202| steroid metabolic process UGT1A1;PRKAA1 GO:0008152| metabolic process ACSS1;PYGL;ACSS2;ACSL1;UGT1A1;FBP1 GO:0071361| cellular response to ethanol PRKAA1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;ACSL1 GO:0007584| response to nutrient UGT1A1;ACSL1 35854:[DB06817 DB00569] DB06817|Raltegravir pol;UGT1A1 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways GO:0007584| response to nutrient UGT1A1;SERPINC1 35855:[DB06817 DB11358] DB06817|Raltegravir pol;UGT1A1 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways 35856:[DB06817 DB09282] DB06817|Raltegravir pol;UGT1A1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0008152| metabolic process UGT1A1;PDE5A 35857:[DB06817 DB00237] DB06817|Raltegravir pol;UGT1A1 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 35858:[DB06817 DB03349] DB06817|Raltegravir pol;UGT1A1 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways 35859:[DB06817 DB11094] DB06817|Raltegravir pol;UGT1A1 DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways GO:0032496| response to lipopolysaccharide CYP27B1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35860:[DB06817 DB05218] DB06817|Raltegravir pol;UGT1A1 DB05218|PN0621 TNF common genes common pathways GO:0010033| response to organic substance TNF;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF 35861:[DB06817 DB09053] DB06817|Raltegravir pol;UGT1A1 DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0006953| acute-phase response ORM1;ORM2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;UGT1A1;CYP3A5 GO:0010033| response to organic substance UGT1A1;BTK GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 35862:[DB06817 DB00276] DB06817|Raltegravir pol;UGT1A1 DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0006953| acute-phase response UGT1A1;ORM1 35863:[DB06817 DB14018] DB06817|Raltegravir pol;UGT1A1 DB14018|Bromotheophylline CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 35864:[DB06817 DB09265] DB06817|Raltegravir pol;UGT1A1 DB09265|Lixisenatide GLP1R common genes common pathways 35865:[DB06817 DB11586] DB06817|Raltegravir pol;UGT1A1 DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6 GO:0042493| response to drug ABCB1;UGT1A1 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2D6;CYP2A6;CYP3A4;CYP3A5;CYP3A7;UGT1A1;CYP2C19 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP2B6;CYP2C19;UGT1A1 35866:[DB06817 DB14065] DB06817|Raltegravir pol;UGT1A1 DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1 35867:[DB06817 DB06460] DB06817|Raltegravir pol;UGT1A1 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways GO:0014070| response to organic cyclic compound EDNRB;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;EDNRB 35868:[DB06817 DB01019] DB06817|Raltegravir pol;UGT1A1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 35869:[DB06817 DB13800] DB06817|Raltegravir pol;UGT1A1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CASQ1 35870:[DB06817 DB08613] DB06817|Raltegravir pol;UGT1A1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0042493| response to drug HDAC4;UGT1A1 35871:[DB06817 DB01496] DB06817|Raltegravir pol;UGT1A1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 35872:[DB06817 DB04948] DB06817|Raltegravir pol;UGT1A1 DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug ADRA1A;UGT1A1;CYP1A2;HTR2C GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP2D6;CYP1A2 GO:0017144| drug metabolic process CYP2D6;CYP1A2;UGT1A1;CYP2C19 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2C19;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 35873:[DB06817 DB11637] DB06817|Raltegravir pol;UGT1A1 DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0006953| acute-phase response UGT1A1;ORM1 35874:[DB06817 DB13994] DB06817|Raltegravir pol;UGT1A1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 35875:[DB06817 DB00414] DB06817|Raltegravir pol;UGT1A1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways GO:0017144| drug metabolic process CYP2C9;CBR1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C9 35876:[DB06817 DB00565] DB06817|Raltegravir pol;UGT1A1 DB00565|Cisatracurium CHRNA2 common genes common pathways 35877:[DB06817 DB08502] DB06817|Raltegravir pol;UGT1A1 DB08502|Capravirine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35878:[DB06817 DB00494] DB06817|Raltegravir pol;UGT1A1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP2D6 GO:0042493| response to drug COMT;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0032496| response to lipopolysaccharide UGT1A1;COMT GO:1904224| UGT1A1;UGT1A9 GO:0014070| response to organic cyclic compound UGT1A1;COMT GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9 GO:0052695| cellular glucuronidation UGT1A9;UGT1A1 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0008152| metabolic process UGT1A1;UGT1A9 35879:[DB06817 DB01548] DB06817|Raltegravir pol;UGT1A1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 GO:0045471| response to ethanol UGT1A1;OPRM1;OPRK1 35880:[DB06817 DB12093] DB06817|Raltegravir pol;UGT1A1 DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;DRD2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol UGT1A1;DRD2 35881:[DB06817 DB00315] DB06817|Raltegravir pol;UGT1A1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0045471| response to ethanol UGT1A1;HTR1B GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug HTR1B;CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 35882:[DB06817 DB11064] DB06817|Raltegravir pol;UGT1A1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 35883:[DB06817 DB07720] DB06817|Raltegravir pol;UGT1A1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0045471| response to ethanol UGT1A1;CHRNB2 35884:[DB06817 DB05201] DB06817|Raltegravir pol;UGT1A1 DB05201|V24343 CNR1 common genes common pathways GO:0045471| response to ethanol UGT1A1;CNR1 GO:0007584| response to nutrient UGT1A1;CNR1 GO:0032496| response to lipopolysaccharide CNR1;UGT1A1 35885:[DB06817 DB03566] DB06817|Raltegravir pol;UGT1A1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways 35886:[DB06817 DB09331] DB06817|Raltegravir pol;UGT1A1 DB09331|Daratumumab CD38 common genes common pathways GO:0042493| response to drug CD38;UGT1A1 35887:[DB06817 DB06111] DB06817|Raltegravir pol;UGT1A1 DB06111|AB192 MPO common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;MPO 35888:[DB06817 DB01074] DB06817|Raltegravir pol;UGT1A1 DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP2B6;CYP2D6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2B6;CYP2D6;CYP3A4 GO:0042493| response to drug CPT1A;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CPT1A GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 35889:[DB06817 DB05091] DB06817|Raltegravir pol;UGT1A1 DB05091|M0002 AVPR2 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;AVPR2 35890:[DB06817 DB06595] DB06817|Raltegravir pol;UGT1A1 DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP3A4;CYP3A7;CYP2E1;CYP3A5;CYP2C8;CYP2C19;UGT1A1 GO:0031100| organ regeneration UGT1A1;FLT3 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP2B6;CYP1A2;CYP3A4;CYP2E1;CYP2C8;CYP2C19;UGT1A1 GO:0042493| response to drug CYP1A2;CYP2E1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PDGFRB;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;UGT1A1;CYP2C19;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 35891:[DB06817 DB01296] DB06817|Raltegravir pol;UGT1A1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0010033| response to organic substance TNF;UGT1A1 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP2E1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;NFKB2 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;UGT1A1 35892:[DB06817 DB12866] DB06817|Raltegravir pol;UGT1A1 DB12866|Pradigastat SLC22A8 common genes common pathways 35893:[DB06817 DB00849] DB06817|Raltegravir pol;UGT1A1 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP2B6;NR1I2;UGT1A1;CYP2C19 GO:0017144| drug metabolic process CYP2B6;UGT1A1;CYP2C19 35894:[DB06817 DB01412] DB06817|Raltegravir pol;UGT1A1 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP1A2 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1;ADORA2A;CYP2E1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2E1;UGT1A1 35895:[DB06817 DB04674] DB06817|Raltegravir pol;UGT1A1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0007586| digestion AKR1C1;UGT1A1 35896:[DB06817 DB04827] DB06817|Raltegravir pol;UGT1A1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0008152| metabolic process UGT1A1;PLA2G4A GO:0032496| response to lipopolysaccharide UGT1A1;MPO GO:0017144| drug metabolic process UGT1A1;AOX1 35897:[DB06817 DB00521] DB06817|Raltegravir pol;UGT1A1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 35898:[DB06817 DB00549] DB06817|Raltegravir pol;UGT1A1 DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;UGT1A1;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1;ABCG2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2C8;UGT1A1;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP1A2;CYP2C19;CYP2C8;UGT1A1;CYP2E1 GO:0010033| response to organic substance CYP1A2;UGT1A1 35899:[DB06817 DB05419] DB06817|Raltegravir pol;UGT1A1 DB05419|ADX-10061 CALY common genes common pathways 35900:[DB06817 DB06700] DB06817|Raltegravir pol;UGT1A1 DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug SLC6A4;SLC6A2;UGT1A1 35901:[DB06817 DB00852] DB06817|Raltegravir pol;UGT1A1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0042493| response to drug UGT1A1;SLC6A2;FOS;ADRA1A;SLC6A3;JUN;SLC6A4 GO:0032496| response to lipopolysaccharide UGT1A1;JUN;FOS GO:0010033| response to organic substance SLC6A4;UGT1A1;TNF;JUN GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0045471| response to ethanol IL2;SLC6A3;UGT1A1 GO:0001889| liver development JUN;UGT1A1 GO:0014070| response to organic cyclic compound JUN;ATF1;FOS;SLC6A3;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;FOS;JUN;ADRA2A 35902:[DB06817 DB06769] DB06817|Raltegravir pol;UGT1A1 DB06769|Bendamustine CYP1A2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 35903:[DB06817 DB05022] DB06817|Raltegravir pol;UGT1A1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways 35904:[DB06817 DB00192] DB06817|Raltegravir pol;UGT1A1 DB00192|Indecainide SCN5A common genes common pathways 35905:[DB06817 DB00534] DB06817|Raltegravir pol;UGT1A1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0008152| metabolic process ALDH5A1;UGT1A1 35906:[DB06817 DB00229] DB06817|Raltegravir pol;UGT1A1 DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways 35907:[DB06817 DB05210] DB06817|Raltegravir pol;UGT1A1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0007584| response to nutrient UGT1A1;MTOR 35908:[DB06817 DB01588] DB06817|Raltegravir pol;UGT1A1 DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35909:[DB06817 DB00963] DB06817|Raltegravir pol;UGT1A1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 35910:[DB06817 DB00396] DB06817|Raltegravir pol;UGT1A1 DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0045471| response to ethanol OPRK1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP1A1;CYP3A4;CYP2D6 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0008202| steroid metabolic process CYP3A7;CYP17A1;CYP3A5;CYP1A1;CYP2C8;CYP2C19;UGT1A1;CYP2D6;CYP2C9;NR1I2;CYP3A4;CYP2A6;CYP1B1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C8;CYP1A1;CYP3A4;CYP2A6;CYP2C9;CYP2D6 GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0042493| response to drug ABCB1;CYP1A1;ABCC1;UGT1A1;ABCG2 GO:0006953| acute-phase response UGT1A1;ORM1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 35911:[DB06817 DB06138] DB06817|Raltegravir pol;UGT1A1 DB06138|IRL-1620 EDNRB common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;EDNRB GO:0014070| response to organic cyclic compound EDNRB;UGT1A1 35912:[DB06817 DB00289] DB06817|Raltegravir pol;UGT1A1 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0045471| response to ethanol GRIN1;SLC6A3;UGT1A1;GRIN3A;GRIN2A;GRIN2B GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0042493| response to drug GRIN2A;SLC6A4;SLC6A3;SLC6A2;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1;CYP2C19 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2D6 GO:0010033| response to organic substance UGT1A1;SLC6A4 35913:[DB06817 DB11491] DB06817|Raltegravir pol;UGT1A1 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 35914:[DB06817 DB06751] DB06817|Raltegravir pol;UGT1A1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways 35915:[DB06817 DB04926] DB06817|Raltegravir pol;UGT1A1 DB04926|Neramexane GRIN3A common genes common pathways GO:0045471| response to ethanol UGT1A1;GRIN3A 35916:[DB06817 DB01650] DB06817|Raltegravir pol;UGT1A1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways 35917:[DB06817 DB01257] DB06817|Raltegravir pol;UGT1A1 DB01257|Eculizumab C5 common genes common pathways 35918:[DB06817 DB00150] DB06817|Raltegravir pol;UGT1A1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0032496| response to lipopolysaccharide IDO1;UGT1A1 GO:0051384| response to glucocorticoid stimulus TPH2;UGT1A1 35919:[DB06817 DB12035] DB06817|Raltegravir pol;UGT1A1 DB12035|Sarecycline ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 35920:[DB06817 DB11577] DB06817|Raltegravir pol;UGT1A1 DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug UGT1A1;ADRA1A GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 35921:[DB06817 DB01288] DB06817|Raltegravir pol;UGT1A1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways 35922:[DB06817 DB08827] DB06817|Raltegravir pol;UGT1A1 DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35923:[DB06817 DB06155] DB06817|Raltegravir pol;UGT1A1 DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways GO:0007584| response to nutrient UGT1A1;CNR1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol CNR1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0032496| response to lipopolysaccharide UGT1A1;CNR1 35924:[DB06817 DB06274] DB06817|Raltegravir pol;UGT1A1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRM1;OPRK1 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 35925:[DB06817 DB11431] DB06817|Raltegravir pol;UGT1A1 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;UGT1A1;CYP3A4 35926:[DB06817 DB06292] DB06817|Raltegravir pol;UGT1A1 DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A1;UGT2B7;UGT1A9;UGT2B4 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;UGT1A1;CYP1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0008152| metabolic process UGT2B7;UGT1A1;UGT2B4;UGT1A9 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0042493| response to drug CYP1A1;UGT1A1;CYP1A2;ABCB1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;CYP1A1 GO:1904224| UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;UGT2B7;UGT1A1;CYP2D6;CYP2C9;CYP1A2;CYP2A6;CYP3A4 GO:0017144| drug metabolic process UGT1A9;CYP2A6;CYP3A4;CYP2D6;CYP2C9;CYP1A2;UGT1A1;CYP1A1 35927:[DB06817 DB05688] DB06817|Raltegravir pol;UGT1A1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0042493| response to drug SLC6A2;UGT1A1;SLC6A4 GO:0010033| response to organic substance UGT1A1;SLC6A4 35928:[DB06817 DB00567] DB06817|Raltegravir pol;UGT1A1 DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35929:[DB06817 DB04958] DB06817|Raltegravir pol;UGT1A1 DB04958|Epratuzumab CD22 common genes common pathways 35930:[DB06817 DB01483] DB06817|Raltegravir pol;UGT1A1 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;UGT1A1 35931:[DB06817 DB00130] DB06817|Raltegravir pol;UGT1A1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CAD GO:0031100| organ regeneration CAD;UGT1A1;PPAT GO:0042594| response to starvation UGT1A1;CAD GO:0042493| response to drug PFAS;PPAT;CTPS1;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ASNS GO:0001889| liver development CAD;UGT1A1;ASNS GO:0008152| metabolic process CAD;UGT1A1;PPAT 35932:[DB06817 DB06579] DB06817|Raltegravir pol;UGT1A1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 35933:[DB06817 DB14069] DB06817|Raltegravir pol;UGT1A1 DB14069|ONT-093 ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 35934:[DB06817 DB00978] DB06817|Raltegravir pol;UGT1A1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;ABCC2;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2;ABCC2 35935:[DB06817 DB06714] DB06817|Raltegravir pol;UGT1A1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways 35936:[DB06817 DB05034] DB06817|Raltegravir pol;UGT1A1 DB05034|Ularitide NPR1 common genes common pathways 35937:[DB06817 DB06603] DB06817|Raltegravir pol;UGT1A1 DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0042493| response to drug HDAC4;HDAC5;ABCB1;HDAC1;HDAC2;UGT1A1 GO:0032496| response to lipopolysaccharide HDAC2;UGT1A1;HDAC1 GO:0010033| response to organic substance HDAC6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;UGT1A1 35938:[DB06817 DB09030] DB06817|Raltegravir pol;UGT1A1 DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways GO:0032496| response to lipopolysaccharide F2R;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35939:[DB06817 DB06342] DB06817|Raltegravir pol;UGT1A1 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35940:[DB06817 DB04299] DB06817|Raltegravir pol;UGT1A1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0051384| response to glucocorticoid stimulus GOT1;UGT1A1 35941:[DB06817 DB07194] DB06817|Raltegravir pol;UGT1A1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways 35942:[DB06817 DB09108] DB06817|Raltegravir pol;UGT1A1 DB09108|Simoctocog Alfa VWF common genes common pathways 35943:[DB06817 DB00713] DB06817|Raltegravir pol;UGT1A1 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 35944:[DB06817 DB14055] DB06817|Raltegravir pol;UGT1A1 DB14055|(S)-Warfarin CYP3A4;CYP2C8;CYP2C9;CYP2C18;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0017144| drug metabolic process CYP2C9;CYP3A4;UGT1A1;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4;CYP2C9 35945:[DB06817 DB00305] DB06817|Raltegravir pol;UGT1A1 DB00305|Mitomycin POR common genes common pathways GO:0042493| response to drug POR;UGT1A1 GO:0007584| response to nutrient POR;UGT1A1 35946:[DB06817 DB09195] DB06817|Raltegravir pol;UGT1A1 DB09195|Lorpiprazole HTR2A;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;SLC6A4;CYP2D6;CYP3A4;ALB common genes common pathways GO:0042493| response to drug ADRA1A;HTR2A;UGT1A1;HTR2C;SLC6A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007584| response to nutrient SLC6A4;UGT1A1 35947:[DB06817 DB01047] DB06817|Raltegravir pol;UGT1A1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 35948:[DB06817 DB08904] DB06817|Raltegravir pol;UGT1A1 DB08904|Certolizumab pegol TNF common genes common pathways GO:0010033| response to organic substance TNF;UGT1A1 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 35949:[DB06817 DB08900] DB06817|Raltegravir pol;UGT1A1 DB08900|Teduglutide GLP2R common genes common pathways 35950:[DB06817 DB13167] DB06817|Raltegravir pol;UGT1A1 DB13167|Alclofenac PTGS2 common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 35951:[DB06817 DB07567] DB06817|Raltegravir pol;UGT1A1 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 35952:[DB06817 DB01307] DB06817|Raltegravir pol;UGT1A1 DB01307|Insulin Detemir INSR;ALB common genes common pathways 35953:[DB06817 DB01571] DB06817|Raltegravir pol;UGT1A1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 35954:[DB06817 DB00353] DB06817|Raltegravir pol;UGT1A1 DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug UGT1A1;HTR2B;DRD1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35955:[DB06817 DB01408] DB06817|Raltegravir pol;UGT1A1 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0007584| response to nutrient UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0042493| response to drug BCHE;UGT1A1 35956:[DB06817 DB08737] DB06817|Raltegravir pol;UGT1A1 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 35957:[DB06817 DB08820] DB06817|Raltegravir pol;UGT1A1 DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP3A5;UGT1A1 GO:0006953| acute-phase response UGT1A1;ORM1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35958:[DB06817 DB00324] DB06817|Raltegravir pol;UGT1A1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 35959:[DB06817 DB04938] DB06817|Raltegravir pol;UGT1A1 DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2D6;CYP3A4;UGT1A1;CYP2C19 GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2D6;CYP3A4;UGT1A1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP3A4 35960:[DB06817 DB13961] DB06817|Raltegravir pol;UGT1A1 DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;FFAR4 GO:0014070| response to organic cyclic compound UGT1A1;SREBF1;PTGS2;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0032496| response to lipopolysaccharide PTGS2;NFKB2;UGT1A1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0042493| response to drug PPARG;UGT1A1;SREBF1;PTGS2 GO:0008202| steroid metabolic process UGT1A1;SREBF1;CYP3A4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0010033| response to organic substance PPARG;PPARD;UGT1A1;PTGS2 35961:[DB06817 DB00261] DB06817|Raltegravir pol;UGT1A1 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;PDE3A;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 35962:[DB06817 DB00444] DB06817|Raltegravir pol;UGT1A1 DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0042493| response to drug ABCC6;UGT1A1;ABCG2 GO:0008202| steroid metabolic process CYP3A5;UGT1A1;CYP2C19;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2C9 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 35963:[DB06817 DB01942] DB06817|Raltegravir pol;UGT1A1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0042167| heme catabolic process HMOX1;UGT1A1 GO:0008152| metabolic process CTBP1;GPHN;UGT1A1 GO:0010033| response to organic substance UGT1A1;CA2 GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 35964:[DB06817 DB13508] DB06817|Raltegravir pol;UGT1A1 DB13508|Cloranolol CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 35965:[DB06817 DB06711] DB06817|Raltegravir pol;UGT1A1 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways GO:0042493| response to drug ADRA1A;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 35966:[DB06817 DB02489] DB06817|Raltegravir pol;UGT1A1 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 35967:[DB06817 DB13954] DB06817|Raltegravir pol;UGT1A1 DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes UGT1A1 common pathways GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2C19;UGT1A1;CYP1A2;CYP3A4 GO:0001889| liver development UGT1A1;CYP1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP2C9;CYP1A2;CYP3A4;CYP1A1;UGT1A1;CYP2C8;CYP2C19 GO:0008202| steroid metabolic process CYP1A2;CYP2C9;NR1I2;CYP3A4;CYP1B1;CYP3A7;CYP1A1;CYP3A5;UGT1A1;CYP2C19;CYP2C8 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR2;ESR1;GPER1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0042493| response to drug CYP1A2;ABCB1;BECN1;CYP1A1;ABCG2;UGT1A1 GO:0007586| digestion FABP2;UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;CYP1A2 GO:1904224| UGT1A1 35968:[DB06817 DB03802] DB06817|Raltegravir pol;UGT1A1 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 35969:[DB06817 DB04365] DB06817|Raltegravir pol;UGT1A1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 35970:[DB06817 DB00075] DB06817|Raltegravir pol;UGT1A1 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007584| response to nutrient CD3E;UGT1A1 35971:[DB06817 DB09063] DB06817|Raltegravir pol;UGT1A1 DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35972:[DB06817 DB00607] DB06817|Raltegravir pol;UGT1A1 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 35973:[DB06817 DB05932] DB06817|Raltegravir pol;UGT1A1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways 35974:[DB06817 DB06786] DB06817|Raltegravir pol;UGT1A1 DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 35975:[DB06817 DB00514] DB06817|Raltegravir pol;UGT1A1 DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2D6;CYP3A4;CYP3A7;CYP2E1;CYP3A5;UGT1A1;CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP2D6;CYP3A4;CYP2E1;UGT1A1;CYP2C8;CYP2C19 GO:0042493| response to drug CYBA;UGT1A1;SLC6A2;CYBB;CYP2E1;SLC6A4 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 GO:0007584| response to nutrient SLC6A4;CYBB;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2E1;CYP3A4;CYP2D6 GO:0045471| response to ethanol UGT1A1;GRIN3A;CYP2E1;OPRM1;OPRK1;CHRNB2 GO:0071361| cellular response to ethanol CYBB;UGT1A1 35976:[DB06817 DB13141] DB06817|Raltegravir pol;UGT1A1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP3A7;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35977:[DB06817 DB13867] DB06817|Raltegravir pol;UGT1A1 DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 35978:[DB06817 DB12092] DB06817|Raltegravir pol;UGT1A1 DB12092|Naftopidil CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 35979:[DB06817 DB00134] DB06817|Raltegravir pol;UGT1A1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0042493| response to drug UGT1A1;MTHFR GO:0008152| metabolic process MTHFR;UGT1A1 35980:[DB06817 DB02943] DB06817|Raltegravir pol;UGT1A1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways GO:0008152| metabolic process UGT1A1;GSTA1 35981:[DB06817 DB07280] DB06817|Raltegravir pol;UGT1A1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 35982:[DB06817 DB13923] DB06817|Raltegravir pol;UGT1A1 DB13923|Emicizumab F9;F10 common genes common pathways 35983:[DB06817 DB14061] DB06817|Raltegravir pol;UGT1A1 DB14061|Hycanthone ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 35984:[DB06817 DB00112] DB06817|Raltegravir pol;UGT1A1 DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 35985:[DB06817 DB09034] DB06817|Raltegravir pol;UGT1A1 DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways GO:0032870| cellular response to hormone stimulus HCRTR1;UGT1A1;HCRTR2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35986:[DB06817 DB06458] DB06817|Raltegravir pol;UGT1A1 DB06458|Remacemide CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 35987:[DB06817 DB07840] DB06817|Raltegravir pol;UGT1A1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways 35988:[DB06817 DB01295] DB06817|Raltegravir pol;UGT1A1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0042493| response to drug UGT1A1;ADRA1A 35989:[DB06817 DB01336] DB06817|Raltegravir pol;UGT1A1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways 35990:[DB06817 DB04539] DB06817|Raltegravir pol;UGT1A1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways 35991:[DB06817 DB00823] DB06817|Raltegravir pol;UGT1A1 DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 35992:[DB06817 DB05372] DB06817|Raltegravir pol;UGT1A1 DB05372|CP-945598 CNR1 common genes common pathways GO:0007584| response to nutrient CNR1;UGT1A1 GO:0045471| response to ethanol CNR1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CNR1 35993:[DB06817 DB00174] DB06817|Raltegravir pol;UGT1A1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0032870| cellular response to hormone stimulus ASNS;UGT1A1 GO:0001889| liver development UGT1A1;ASNS 35994:[DB06817 DB04873] DB06817|Raltegravir pol;UGT1A1 DB04873|Piboserod HTR4 common genes common pathways 35995:[DB06817 DB01154] DB06817|Raltegravir pol;UGT1A1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1;KCNJ11 GO:0032496| response to lipopolysaccharide KCNJ8;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP2C9;CYP3A4 35996:[DB06817 DB05501] DB06817|Raltegravir pol;UGT1A1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways 35997:[DB06817 DB01426] DB06817|Raltegravir pol;UGT1A1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0006953| acute-phase response UGT1A1;ORM1 35998:[DB06817 DB00462] DB06817|Raltegravir pol;UGT1A1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 35999:[DB06817 DB04850] DB06817|Raltegravir pol;UGT1A1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways 36000:[DB06817 DB06266] DB06817|Raltegravir pol;UGT1A1 DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0008152| metabolic process HK1;UGT1A1 36001:[DB06817 DB04858] DB06817|Raltegravir pol;UGT1A1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1 36002:[DB06817 DB11672] DB06817|Raltegravir pol;UGT1A1 DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0010033| response to organic substance PPARG;CYP1A2;UGT1A1 GO:0031100| organ regeneration UGT1A1;GSTP1;PPARG GO:0017144| drug metabolic process CYP2D6;CYP2B6;CYP2C9;CYP1A2;CYP3A4;UGT1A1;CBR1 GO:0008202| steroid metabolic process CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0042493| response to drug CYP1A2;PPARG;ABCB1;UGT1A1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG;CYP1A2 GO:0008152| metabolic process GSTA1;UGT1A1;GSTP1;GSTM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2;CYP2D6 GO:0045471| response to ethanol GSTP1;UGT1A1 36003:[DB06817 DB05457] DB06817|Raltegravir pol;UGT1A1 DB05457|OSI-7904L TYMS common genes common pathways GO:0042493| response to drug TYMS;UGT1A1 GO:0045471| response to ethanol TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0014070| response to organic cyclic compound TYMS;UGT1A1 36004:[DB06817 DB02032] DB06817|Raltegravir pol;UGT1A1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 36005:[DB06817 DB00668] DB06817|Raltegravir pol;UGT1A1 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0017144| drug metabolic process CYP2C9;CYP3A4;UGT1A1 GO:0010033| response to organic substance TNF;UGT1A1 GO:0032496| response to lipopolysaccharide COMT;MAOB;UGT1A1 GO:0042493| response to drug COMT;ADRA1A;MAOB;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0014070| response to organic cyclic compound UGT1A1;COMT GO:0045471| response to ethanol UGT1A1;MAOB GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36006:[DB06817 DB09295] DB06817|Raltegravir pol;UGT1A1 DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 36007:[DB06817 DB00328] DB06817|Raltegravir pol;UGT1A1 DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes UGT1A1 common pathways GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2;PPARG;ABCC4 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0008202| steroid metabolic process AKR1C3;CYP2C9;UGT1A1;CYP2C19;UGT2B7 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A9;CYP2C9;CYP2C19;UGT1A1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug ABCB1;ABCC2;PPARG;ABCC4;PTGS2;UGT1A1;ABCC1;ABCC6 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:1904224| UGT1A1;UGT1A9 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;ABCC2 GO:0042594| response to starvation UGT1A1;PPARG GO:0007586| digestion UGT1A1 GO:0014070| response to organic cyclic compound ABCC4;PPARG;PTGS2;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0007584| response to nutrient UGT1A1;AKR1C3;PPARG GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0052695| cellular glucuronidation UGT1A9;UGT2B7;UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9 GO:0001889| liver development UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A9;UGT2B7;CES1;UGT1A1 36008:[DB06817 DB00394] DB06817|Raltegravir pol;UGT1A1 DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0008202| steroid metabolic process CYP3A5;UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36009:[DB06817 DB00286] DB06817|Raltegravir pol;UGT1A1 DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;COMT;ABCC4;CYP1A2 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0042493| response to drug ABCB1;ABCC2;COMT;CYP1A2;ABCC4;ABCC1;UGT1A1;ABCG2 GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2;COMT;CYP1A2 GO:0010033| response to organic substance CYP1A2;ABCC4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP3A4 36010:[DB06817 DB05395] DB06817|Raltegravir pol;UGT1A1 DB05395|Amibegron ADRB3 common genes common pathways 36011:[DB06817 DB00532] DB06817|Raltegravir pol;UGT1A1 DB00532|Mephenytoin SCN5A;NR1I2;CYP2C19;CYP2B6;CYP1A2;CYP2D6;CYP2C8;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;UGT1A1;CYP2C19 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP2C8;CYP2C19;UGT1A1;CYP1A2;CYP2D6;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2C9;NR1I2;CYP2B6;CYP2D6;CYP1A2;UGT1A1;CYP2C8;CYP2C19 36012:[DB06817 DB14498] DB06817|Raltegravir pol;UGT1A1 DB14498|Potassium acetate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;UGT1A1 36013:[DB06817 DB05478] DB06817|Raltegravir pol;UGT1A1 DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36014:[DB06817 DB00456] DB06817|Raltegravir pol;UGT1A1 DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 36015:[DB06817 DB03214] DB06817|Raltegravir pol;UGT1A1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways 36016:[DB06817 DB11623] DB06817|Raltegravir pol;UGT1A1 DB11623|Candoxatrilat MME common genes common pathways 36017:[DB06817 DB11582] DB06817|Raltegravir pol;UGT1A1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0042493| response to drug GABRG3;UGT1A1 36018:[DB06817 DB06081] DB06817|Raltegravir pol;UGT1A1 DB06081|Caplacizumab VWF common genes common pathways 36019:[DB06817 DB12637] DB06817|Raltegravir pol;UGT1A1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 36020:[DB06817 DB05447] DB06817|Raltegravir pol;UGT1A1 DB05447|AVI-4557 HNF4A common genes common pathways 36021:[DB06817 DB01328] DB06817|Raltegravir pol;UGT1A1 DB01328|Cefonicid mrcA;ALB common genes common pathways 36022:[DB06817 DB04817] DB06817|Raltegravir pol;UGT1A1 DB04817|Metamizole PTGS1;CYP2B6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2B6;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2B6 36023:[DB06817 DB00202] DB06817|Raltegravir pol;UGT1A1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 GO:0042493| response to drug UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 36024:[DB06817 DB13178] DB06817|Raltegravir pol;UGT1A1 DB13178|Inositol SLC5A3 common genes common pathways 36025:[DB06817 DB11692] DB06817|Raltegravir pol;UGT1A1 DB11692|Pavinetant TACR3 common genes common pathways 36026:[DB06817 DB06735] DB06817|Raltegravir pol;UGT1A1 DB06735|Enclomiphene CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 36027:[DB06817 DB06697] DB06817|Raltegravir pol;UGT1A1 DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP3A5;CYP3A4;CYP2B6;CYP2C9;CYP2D6 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6;CYP2B6;CYP2C9 36028:[DB06817 DB04381] DB06817|Raltegravir pol;UGT1A1 DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0008152| metabolic process UGT1A1;ALDH2 36029:[DB06817 DB03991] DB06817|Raltegravir pol;UGT1A1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways GO:0008152| metabolic process NEU2;UGT1A1 36030:[DB06817 DB05200] DB06817|Raltegravir pol;UGT1A1 DB05200|AT2220 GAA common genes common pathways GO:0008152| metabolic process UGT1A1;GAA 36031:[DB06817 DB14063] DB06817|Raltegravir pol;UGT1A1 DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36032:[DB06817 DB04953] DB06817|Raltegravir pol;UGT1A1 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes UGT1A1 common pathways GO:0014070| response to organic cyclic compound UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9;UGT1A3 GO:0007584| response to nutrient UGT1A1 GO:0042167| heme catabolic process UGT1A1;UGT1A4 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A4;UGT1A1;UGT1A3;UGT1A9 GO:0052695| cellular glucuronidation UGT1A9;UGT1A3;UGT1A1;UGT1A4 GO:0006789| bilirubin conjugation UGT1A4;UGT1A1 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A4;UGT1A3;UGT1A9;NAT2 GO:0071361| cellular response to ethanol UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A4;UGT1A9;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A4;UGT1A1;UGT1A3;UGT1A9 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A9;UGT1A1;UGT1A4 GO:0010033| response to organic substance UGT1A1 GO:0008202| steroid metabolic process UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A4;UGT1A1;UGT1A3;UGT1A9 GO:0042493| response to drug UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:1904224| UGT1A3;UGT1A9;UGT1A4;UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 36033:[DB06817 DB06707] DB06817|Raltegravir pol;UGT1A1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 36034:[DB06817 DB09143] DB06817|Raltegravir pol;UGT1A1 DB09143|Sonidegib SMO;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36035:[DB06817 DB00293] DB06817|Raltegravir pol;UGT1A1 DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0031100| organ regeneration UGT1A1;FPGS GO:0042493| response to drug TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0045471| response to ethanol UGT1A1;TYMS GO:0001889| liver development FPGS;UGT1A1 36036:[DB06817 DB00835] DB06817|Raltegravir pol;UGT1A1 DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0007586| digestion CHRM3;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP2C8;CYP2C19;CYP2B6;CYP3A4 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2E1;UGT1A1;CYP2C8;CYP2C19 36037:[DB06817 DB00576] DB06817|Raltegravir pol;UGT1A1 DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;UGT1A1 36038:[DB06817 DB01213] DB06817|Raltegravir pol;UGT1A1 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1;CAT GO:0008202| steroid metabolic process CYP2A6;UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;ADH1A;CYP2A6 GO:0042493| response to drug CYP2E1;UGT1A1;CAT 36039:[DB06817 DB00718] DB06817|Raltegravir pol;UGT1A1 DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0001889| liver development UGT1A1;AK4 GO:0010033| response to organic substance UGT1A1;ABCC4 GO:0042493| response to drug ABCC4;AK4;NME1;UGT1A1 36040:[DB06817 DB00368] DB06817|Raltegravir pol;UGT1A1 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0008152| metabolic process UGT1A1;PAH GO:0042493| response to drug SLC6A2;UGT1A1;ADRA1A 36041:[DB06817 DB00151] DB06817|Raltegravir pol;UGT1A1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0045471| response to ethanol MGMT;UGT1A1;CDO1 GO:0008152| metabolic process UGT1A1;CBS GO:0014070| response to organic cyclic compound MGMT;UGT1A1 GO:0007584| response to nutrient UGT1A1;GCLM;GCLC GO:0051384| response to glucocorticoid stimulus CDO1;UGT1A1;GOT1 GO:0042493| response to drug GCLM;UGT1A1;MGMT 36042:[DB06817 DB02751] DB06817|Raltegravir pol;UGT1A1 DB02751|Glycocyamine GAMT common genes common pathways 36043:[DB06817 DB03185] DB06817|Raltegravir pol;UGT1A1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 36044:[DB06817 DB00074] DB06817|Raltegravir pol;UGT1A1 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways 36045:[DB06817 DB00755] DB06817|Raltegravir pol;UGT1A1 DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes common pathways GO:0042573| retinoic acid metabolic process ALDH1A2;CYP26B1;CYP26A1;UGT1A1;CRABP2 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0008152| metabolic process UGT1A1;ALDH1A2;ALDH1A1 GO:0001889| liver development CYP1A1;UGT1A1;RARA;ALDH1A2 GO:0045471| response to ethanol UGT1A1;RARA;RBP4 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP1A1;CYP2A6;CYP3A4;CYP2B6;CYP2C9 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A1;CYP3A5;CYP3A7;CYP2A6;CYP3A4;CYP2B6;CYP2C9 GO:0042493| response to drug UGT1A1;CYP1A1 GO:0042594| response to starvation PDK4;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1 36046:[DB06817 DB03516] DB06817|Raltegravir pol;UGT1A1 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0017144| drug metabolic process UGT1A1;AOX1 36047:[DB06817 DB00749] DB06817|Raltegravir pol;UGT1A1 DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways GO:0017144| drug metabolic process UGT1A9;UGT1A3;CYP2C9;UGT1A1;UGT1A10 GO:0008202| steroid metabolic process CYP2C9;UGT2B7;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A3;UGT1A1;UGT1A10 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A9;UGT1A10;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A10;UGT1A9;UGT1A3 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:1904224| UGT1A1;UGT1A10;UGT1A9;UGT1A3 GO:0042493| response to drug PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A3;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008152| metabolic process UGT1A10;UGT2B7;UGT1A1;UGT1A9;UGT1A3 GO:0051552| flavone metabolic process UGT1A1;UGT1A10;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A10;UGT1A9;UGT1A3 GO:0052695| cellular glucuronidation UGT2B7;UGT1A10;UGT1A1;UGT1A3;UGT1A9 36048:[DB06817 DB03128] DB06817|Raltegravir pol;UGT1A1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 36049:[DB06817 DB01306] DB06817|Raltegravir pol;UGT1A1 DB01306|Insulin Aspart INSR common genes common pathways 36050:[DB06817 DB14570] DB06817|Raltegravir pol;UGT1A1 DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36051:[DB06817 DB05773] DB06817|Raltegravir pol;UGT1A1 DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A5;UGT1A1 GO:0042493| response to drug UGT1A1;ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36052:[DB06817 DB00148] DB06817|Raltegravir pol;UGT1A1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways 36053:[DB06817 DB06090] DB06817|Raltegravir pol;UGT1A1 DB06090|Bradanicline CHRNA7 common genes common pathways 36054:[DB06817 DB01614] DB06817|Raltegravir pol;UGT1A1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1 GO:0042493| response to drug DRD1;HTR2A;DRD2;ADRA1A;UGT1A1 36055:[DB06817 DB13151] DB06817|Raltegravir pol;UGT1A1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0014070| response to organic cyclic compound F7;UGT1A1 GO:0006953| acute-phase response UGT1A1;F2;F8 GO:0031100| organ regeneration F7;UGT1A1 36056:[DB06817 DB01431] DB06817|Raltegravir pol;UGT1A1 DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36057:[DB06817 DB01610] DB06817|Raltegravir pol;UGT1A1 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 36058:[DB06817 DB01382] DB06817|Raltegravir pol;UGT1A1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0042493| response to drug UGT1A1;ABCC8 GO:0032496| response to lipopolysaccharide ABCC8;UGT1A1 36059:[DB06817 DB08836] DB06817|Raltegravir pol;UGT1A1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 36060:[DB06817 DB01600] DB06817|Raltegravir pol;UGT1A1 DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 36061:[DB06817 DB09099] DB06817|Raltegravir pol;UGT1A1 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0007584| response to nutrient SSTR2;SSTR1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0071392| cellular response to estradiol stimulus UGT1A1;SSTR2;SSTR1;SSTR3 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0007586| digestion SSTR2;SSTR1;UGT1A1 GO:0042594| response to starvation SSTR3;SSTR2;SSTR1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus SSTR2;UGT1A1;SSTR5;SSTR4;SSTR3 GO:0042493| response to drug UGT1A1;ABCB1 36062:[DB06817 DB06699] DB06817|Raltegravir pol;UGT1A1 DB06699|Degarelix GNRHR common genes common pathways 36063:[DB06817 DB05687] DB06817|Raltegravir pol;UGT1A1 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1 GO:0042493| response to drug DRD2;HTR2A;UGT1A1 36064:[DB06817 DB06822] DB06817|Raltegravir pol;UGT1A1 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0031100| organ regeneration CXCL12;UGT1A1 GO:0007584| response to nutrient SERPINC1;UGT1A1 36065:[DB06817 DB00200] DB06817|Raltegravir pol;UGT1A1 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0008152| metabolic process UGT1A1;MUT GO:0008202| steroid metabolic process CUBN;UGT1A1 36066:[DB06817 DB09564] DB06817|Raltegravir pol;UGT1A1 DB09564|Insulin Degludec INSR common genes common pathways 36067:[DB06817 DB11921] DB06817|Raltegravir pol;UGT1A1 DB11921|Deflazacort CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36068:[DB06817 DB01289] DB06817|Raltegravir pol;UGT1A1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C9 GO:0032496| response to lipopolysaccharide UGT1A1;KCNJ8 36069:[DB06817 DB00357] DB06817|Raltegravir pol;UGT1A1 DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP11A1;CYP3A4;CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4 36070:[DB06817 DB06191] DB06817|Raltegravir pol;UGT1A1 DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 36071:[DB06817 DB01014] DB06817|Raltegravir pol;UGT1A1 DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0042594| response to starvation UGT1A1;PPARG GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug PPARG;UGT1A1;PTGS2 GO:0031100| organ regeneration UGT1A1;PPARG GO:0010033| response to organic substance PTGS2;UGT1A1;PPARG GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;PPARG 36072:[DB06817 DB04334] DB06817|Raltegravir pol;UGT1A1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways 36073:[DB06817 DB09309] DB06817|Raltegravir pol;UGT1A1 DB09309|Kitasamycin CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36074:[DB06817 DB01056] DB06817|Raltegravir pol;UGT1A1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 36075:[DB06817 DB11077] DB06817|Raltegravir pol;UGT1A1 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;ADH5 GO:0008210| estrogen metabolic process UGT1A1;SULT1A1 GO:0008202| steroid metabolic process UGT1A1;SULT1A1 GO:0008152| metabolic process ENPP1;UGT1A1 36076:[DB06817 DB11487] DB06817|Raltegravir pol;UGT1A1 DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36077:[DB06817 DB01354] DB06817|Raltegravir pol;UGT1A1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 36078:[DB06817 DB01255] DB06817|Raltegravir pol;UGT1A1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0007586| digestion SLC15A1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;UGT1A1 36079:[DB06817 DB01253] DB06817|Raltegravir pol;UGT1A1 DB01253|Ergometrine ADRA1A;CYP3A4;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;ADRA1A GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36080:[DB06817 DB04263] DB06817|Raltegravir pol;UGT1A1 DB04263|Geneticin ODC1 common genes common pathways 36081:[DB06817 DB00344] DB06817|Raltegravir pol;UGT1A1 DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0042493| response to drug SLC6A4;ABCB1;UGT1A1;SLC6A2 36082:[DB06817 DB06420] DB06817|Raltegravir pol;UGT1A1 DB06420|Annamycin TOP2A common genes common pathways 36083:[DB06817 DB09238] DB06817|Raltegravir pol;UGT1A1 DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP2C19;CYP2D6;CYP3A4 GO:0001889| liver development CYP1A1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;CACNA1H GO:0042493| response to drug CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1 GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2D6;CYP3A4;CYP1A1;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP1A1;UGT1A1;CYP2C19;CYP2C9;CYP2B6;CYP2D6;CYP3A4 36084:[DB06817 DB00547] DB06817|Raltegravir pol;UGT1A1 DB00547|Desoximetasone NR3C1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 36085:[DB06817 DB00868] DB06817|Raltegravir pol;UGT1A1 DB00868|Benzonatate SCN5A common genes common pathways 36086:[DB06817 DB00255] DB06817|Raltegravir pol;UGT1A1 DB00255|Diethylstilbestrol ESR1;ESRRG;ESR2;ESRRA;ESRRB;NCOA2;NR1I2;AR;SHBG;COMT;CYP19A1;CYP3A4;CYP2C8;CYP2C9;CYP2E1;TTR;ABCG2;ABCB1;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound COMT;UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2E1;CYP3A4;CYP2C9 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1;ESR2 GO:0008202| steroid metabolic process CYP2C9;NR1I2;CYP3A4;CYP2E1;UGT1A1;CYP2C8 GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0042493| response to drug CYP2E1;ABCG2;UGT1A1;COMT;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;COMT 36087:[DB06817 DB09103] DB06817|Raltegravir pol;UGT1A1 DB09103|Ancestim KIT common genes common pathways 36088:[DB06817 DB05077] DB06817|Raltegravir pol;UGT1A1 DB05077|SLV319 CNR1 common genes common pathways GO:0007584| response to nutrient CNR1;UGT1A1 GO:0045471| response to ethanol CNR1;UGT1A1 GO:0032496| response to lipopolysaccharide CNR1;UGT1A1 36089:[DB06817 DB04573] DB06817|Raltegravir pol;UGT1A1 DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1;ESR2 GO:0042493| response to drug UGT1A1;ABCB1 36090:[DB06817 DB06963] DB06817|Raltegravir pol;UGT1A1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways 36091:[DB06817 DB00893] DB06817|Raltegravir pol;UGT1A1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways 36092:[DB06817 DB06802] DB06817|Raltegravir pol;UGT1A1 DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 36093:[DB06817 DB01764] DB06817|Raltegravir pol;UGT1A1 DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36094:[DB06817 DB06144] DB06817|Raltegravir pol;UGT1A1 DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0045471| response to ethanol UGT1A1;DRD2 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0042493| response to drug HTR2A;ADRA1A;DRD2;UGT1A1;HTR2C GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 36095:[DB06817 DB00797] DB06817|Raltegravir pol;UGT1A1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug UGT1A1;ADRA1A 36096:[DB06817 DB00345] DB06817|Raltegravir pol;UGT1A1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0042493| response to drug ABCC1;UGT1A1;ABCC2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 36097:[DB06817 DB02783] DB06817|Raltegravir pol;UGT1A1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways GO:0045471| response to ethanol UGT1A1;GOT2 36098:[DB06817 DB06444] DB06817|Raltegravir pol;UGT1A1 DB06444|Dexanabinol TNF common genes common pathways GO:0010033| response to organic substance UGT1A1;TNF GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF 36099:[DB06817 DB14072] DB06817|Raltegravir pol;UGT1A1 DB14072|Reversin 121 ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 36100:[DB06817 DB05758] DB06817|Raltegravir pol;UGT1A1 DB05758|CYT007-TNFQb TNF common genes common pathways GO:0010033| response to organic substance UGT1A1;TNF GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 36101:[DB06817 DB06495] DB06817|Raltegravir pol;UGT1A1 DB06495|Onercept TNF common genes common pathways GO:0010033| response to organic substance TNF;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF 36102:[DB06817 DB11471] DB06817|Raltegravir pol;UGT1A1 DB11471|Tilmicosin CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36103:[DB06817 DB04844] DB06817|Raltegravir pol;UGT1A1 DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CBR1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0042493| response to drug UGT1A1;DRD2 GO:0045471| response to ethanol DRD2;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 36104:[DB06817 DB11278] DB06817|Raltegravir pol;UGT1A1 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug UGT1A1;ADRA1A GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 36105:[DB06817 DB14502] DB06817|Raltegravir pol;UGT1A1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0007584| response to nutrient UGT1A1;SLC34A1 GO:0042493| response to drug SLC34A1;UGT1A1 36106:[DB06817 DB09036] DB06817|Raltegravir pol;UGT1A1 DB09036|Siltuximab IL6;CYP3A4 common genes common pathways GO:0006953| acute-phase response UGT1A1;IL6 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;IL6 36107:[DB06817 DB03542] DB06817|Raltegravir pol;UGT1A1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 36108:[DB06817 DB11979] DB06817|Raltegravir pol;UGT1A1 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1;CYP3A5;CYP3A7 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 36109:[DB06817 DB06510] DB06817|Raltegravir pol;UGT1A1 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes UGT1A1 common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2C8;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A3;CYP2C8;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A3;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:0010033| response to organic substance PPARG;CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:1904224| UGT1A3;UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug CYP1A2;PPARG;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2;PPARG GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A3 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A3;UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A3 GO:0052695| cellular glucuronidation UGT1A1;UGT1A3 GO:0006789| bilirubin conjugation UGT1A1 36110:[DB06817 DB07776] DB06817|Raltegravir pol;UGT1A1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0008202| steroid metabolic process UGT1A1;CYP1B1 36111:[DB06817 DB00922] DB06817|Raltegravir pol;UGT1A1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0032496| response to lipopolysaccharide KCNJ8;UGT1A1 GO:0042493| response to drug UGT1A1;KCNJ11;PDE3A 36112:[DB06817 DB01176] DB06817|Raltegravir pol;UGT1A1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;SULT1E1;CYP2C9 GO:0008210| estrogen metabolic process SULT1E1;UGT1A1 36113:[DB06817 DB09328] DB06817|Raltegravir pol;UGT1A1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042594| response to starvation UGT1A1;ACAT1 GO:0042493| response to drug CYP1A2;CYP2E1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;ACAT1;CYP1A2 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0001889| liver development ACAT1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP1A2 GO:0008152| metabolic process ACAT1;UGT1A1;ACAA1 36114:[DB06817 DB11155] DB06817|Raltegravir pol;UGT1A1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0042493| response to drug CYP1A1;UGT1A1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0008202| steroid metabolic process CYP1B1;UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP1A1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 36115:[DB06817 DB11751] DB06817|Raltegravir pol;UGT1A1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways 36116:[DB06817 DB01203] DB06817|Raltegravir pol;UGT1A1 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 36117:[DB06817 DB04911] DB06817|Raltegravir pol;UGT1A1 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2C9;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C9;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1;CYP2C19 36118:[DB06817 DB11090] DB06817|Raltegravir pol;UGT1A1 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 36119:[DB06817 DB00670] DB06817|Raltegravir pol;UGT1A1 DB00670|Pirenzepine CHRM1 common genes common pathways 36120:[DB06817 DB01169] DB06817|Raltegravir pol;UGT1A1 DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;JUN;HDAC1;CYP1A1;ABCC2;MAPK1;MAPK3 GO:0042493| response to drug CCND1;CYP1A1;HDAC1;JUN;UGT1A1;CDKN1A;ABCC2;ABCB1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0008202| steroid metabolic process CYP1A1;UGT1A1;CYP3A4;CYP1B1 GO:0031100| organ regeneration CCND1;UGT1A1;CDKN1A GO:0017144| drug metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0048545| response to steroid hormone stimulus ABCC2;CCND1;UGT1A1 GO:0010033| response to organic substance CYP1A1;CCND1;JUN;UGT1A1;AKT1;CDKN1A GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1 GO:0001889| liver development CYP1A1;CCND1;JUN;UGT1A1 GO:0045471| response to ethanol CCND1;UGT1A1 GO:0051384| response to glucocorticoid stimulus CDKN1A;CCND1;UGT1A1 GO:0032870| cellular response to hormone stimulus JUN;UGT1A1;ABCC2 GO:0014070| response to organic cyclic compound CDKN1A;JUN;CCND1;CYP1A1;UGT1A1 36121:[DB06817 DB04878] DB06817|Raltegravir pol;UGT1A1 DB04878|Voglibose MGAM common genes common pathways GO:0008152| metabolic process MGAM;UGT1A1 36122:[DB06817 DB00113] DB06817|Raltegravir pol;UGT1A1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways 36123:[DB06817 DB00831] DB06817|Raltegravir pol;UGT1A1 DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ADRA1A;DRD2;ABCB1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:1904224| UGT1A1;UGT1A4 GO:0052696| flavonoid glucuronidation UGT1A4;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A4;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A4 GO:0017144| drug metabolic process CYP1A2;UGT1A1;UGT1A4 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A4 GO:0052695| cellular glucuronidation UGT1A4;UGT1A1 GO:0006789| bilirubin conjugation UGT1A4;UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A4 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0045471| response to ethanol UGT1A1;DRD2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042167| heme catabolic process UGT1A1;UGT1A4 36124:[DB06817 DB00311] DB06817|Raltegravir pol;UGT1A1 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways GO:0045471| response to ethanol CA3;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0010033| response to organic substance CA2;UGT1A1 36125:[DB06817 DB00308] DB06817|Raltegravir pol;UGT1A1 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0042493| response to drug KCNJ11;UGT1A1 36126:[DB06817 DB09237] DB06817|Raltegravir pol;UGT1A1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0032496| response to lipopolysaccharide NOS2;UGT1A1 36127:[DB06817 DB06762] DB06817|Raltegravir pol;UGT1A1 DB06762|Pinacidil CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36128:[DB06817 DB04348] DB06817|Raltegravir pol;UGT1A1 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0042493| response to drug ABCG2;UGT1A1;ABCC1;ABCC4;ABCB1;ABCC2 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0010033| response to organic substance ABCC4;UGT1A1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 36129:[DB06817 DB00463] DB06817|Raltegravir pol;UGT1A1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 36130:[DB06817 DB00680] DB06817|Raltegravir pol;UGT1A1 DB00680|Moricizine SCN5A common genes common pathways 36131:[DB06817 DB00579] DB06817|Raltegravir pol;UGT1A1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0045471| response to ethanol SLC6A3;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0042493| response to drug SLC6A4;SLC6A3;SLC6A2;UGT1A1 36132:[DB06817 DB04895] DB06817|Raltegravir pol;UGT1A1 DB04895|Pegaptanib NRP1 common genes common pathways 36133:[DB06817 DB14499] DB06817|Raltegravir pol;UGT1A1 DB14499|Potassium sulfate ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;UGT1A1 36134:[DB06817 DB06695] DB06817|Raltegravir pol;UGT1A1 DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9 GO:0008152| metabolic process UGT1A9;UGT2B15;UGT1A1;CES1;UGT2B7 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A9;UGT2B7;UGT2B15;UGT1A1 GO:0017144| drug metabolic process UGT1A9;UGT1A1 GO:0008202| steroid metabolic process UGT2B15;UGT1A1;UGT2B7 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 GO:1904224| UGT1A9;UGT1A1 GO:0006953| acute-phase response F2;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1 36135:[DB06817 DB14538] DB06817|Raltegravir pol;UGT1A1 DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008152| metabolic process UGT1A1;HSD3B1 GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0051384| response to glucocorticoid stimulus ANXA1;HSD11B2;UGT1A1 GO:0032870| cellular response to hormone stimulus CYP11B1;CYP11B2;UGT1A1 GO:0042493| response to drug ABCG2;UGT1A1;HSD11B2;ANXA1;ABCB1 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;UGT1A1;NR3C1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP11B2;CYP3A5;CYP3A7;CYP11B1 GO:0048545| response to steroid hormone stimulus HSD11B2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 36136:[DB06817 DB06283] DB06817|Raltegravir pol;UGT1A1 DB06283|Ziconotide CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36137:[DB06817 DB08819] DB06817|Raltegravir pol;UGT1A1 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1;PTGFR GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36138:[DB06817 DB01384] DB06817|Raltegravir pol;UGT1A1 DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36139:[DB06817 DB06712] DB06817|Raltegravir pol;UGT1A1 DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;UGT1A1;CYP2C8;CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP2C19;CYP2C8;CYP2A6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 36140:[DB06817 DB00050] DB06817|Raltegravir pol;UGT1A1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways 36141:[DB06817 DB05983] DB06817|Raltegravir pol;UGT1A1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;NFKBIA 36142:[DB06817 DB09336] DB06817|Raltegravir pol;UGT1A1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways 36143:[DB06817 DB04100] DB06817|Raltegravir pol;UGT1A1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1 GO:0042493| response to drug ABCC2;UGT1A1 36144:[DB06817 DB00126] DB06817|Raltegravir pol;UGT1A1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0008152| metabolic process LCT;UGT1A1;PAM GO:0051384| response to glucocorticoid stimulus UGT1A1;PAM GO:0032870| cellular response to hormone stimulus UGT1A1;PLOD3 GO:0042493| response to drug UGT1A1;PAM 36145:[DB06817 DB01274] DB06817|Raltegravir pol;UGT1A1 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2A6;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP2A6;UGT1A1;CYP2C19 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP2C19 36146:[DB06817 DB09413] DB06817|Raltegravir pol;UGT1A1 DB09413|Monopotassium phosphate ALPI common genes common pathways GO:0008152| metabolic process ALPI;UGT1A1 GO:0007586| digestion UGT1A1;ALPI 36147:[DB06817 DB06360] DB06817|Raltegravir pol;UGT1A1 DB06360|Lucatumumab CD40 common genes common pathways GO:0032496| response to lipopolysaccharide CD40;UGT1A1 36148:[DB06817 DB00035] DB06817|Raltegravir pol;UGT1A1 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0032870| cellular response to hormone stimulus AVPR1B;UGT1A1;AVPR1A;AVPR2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2;AVPR1A GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 36149:[DB06817 DB02745] DB06817|Raltegravir pol;UGT1A1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 36150:[DB06817 DB09217] DB06817|Raltegravir pol;UGT1A1 DB09217|Firocoxib PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 36151:[DB06817 DB00430] DB06817|Raltegravir pol;UGT1A1 DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways 36152:[DB06817 DB03506] DB06817|Raltegravir pol;UGT1A1 DB03506|9-Deazaadenine APRT common genes common pathways 36153:[DB06817 DB12119] DB06817|Raltegravir pol;UGT1A1 DB12119|Gevokizumab IL1B common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;IL1B 36154:[DB06817 DB06636] DB06817|Raltegravir pol;UGT1A1 DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36155:[DB06817 DB00081] DB06817|Raltegravir pol;UGT1A1 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 36156:[DB06817 DB08049] DB06817|Raltegravir pol;UGT1A1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0042493| response to drug COMT;UGT1A1 GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0032496| response to lipopolysaccharide COMT;UGT1A1 GO:0014070| response to organic cyclic compound COMT;UGT1A1 36157:[DB06817 DB11198] DB06817|Raltegravir pol;UGT1A1 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 36158:[DB06817 DB01330] DB06817|Raltegravir pol;UGT1A1 DB01330|Cefotetan ALB common genes common pathways 36159:[DB06817 DB12474] DB06817|Raltegravir pol;UGT1A1 DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C9;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT1A1;CYP2C19 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 36160:[DB06817 DB01043] DB06817|Raltegravir pol;UGT1A1 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0042493| response to drug UGT1A1;DRD2;GRIN2A GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP2A6;CYP2B6 GO:0017144| drug metabolic process CYP2A6;CYP2B6;CYP2C19;UGT1A1 GO:0045471| response to ethanol GRIN2A;GRIN2B;DRD2;HTR3A;GRIN1;UGT1A1;GRIN3A GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19 36161:[DB06817 DB09194] DB06817|Raltegravir pol;UGT1A1 DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A2;UGT1A1;SLC6A3;DRD2;ADRA1A;HTR2A;SLC6A4;HTR2C GO:0007586| digestion CHRM3;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0045471| response to ethanol SLC6A3;DRD2;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 36162:[DB06817 DB00910] DB06817|Raltegravir pol;UGT1A1 DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways GO:0042167| heme catabolic process UGT1A1;UGT1A4 GO:0052695| cellular glucuronidation UGT1A1;UGT1A4 GO:0006789| bilirubin conjugation UGT1A1;UGT1A4 GO:2001030| negative regulation of cellular glucuronidation UGT1A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008152| metabolic process UGT1A4;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A4 GO:0045922| negative regulation of fatty acid metabolic process UGT1A4;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A4;CYP3A4 GO:1904224| UGT1A1;UGT1A4 36163:[DB06817 DB08952] DB06817|Raltegravir pol;UGT1A1 DB08952|Indenolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 36164:[DB06817 DB01107] DB06817|Raltegravir pol;UGT1A1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 36165:[DB06817 DB09073] DB06817|Raltegravir pol;UGT1A1 DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug CDK4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0031100| organ regeneration CDK4;UGT1A1 GO:0010033| response to organic substance CDK4;UGT1A1 36166:[DB06817 DB00424] DB06817|Raltegravir pol;UGT1A1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 36167:[DB06817 DB09045] DB06817|Raltegravir pol;UGT1A1 DB09045|Dulaglutide GLP1R common genes common pathways 36168:[DB06817 DB06307] DB06817|Raltegravir pol;UGT1A1 DB06307|Apoptone BCL2 common genes common pathways GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0042493| response to drug UGT1A1;BCL2 GO:0051384| response to glucocorticoid stimulus BCL2;UGT1A1 36169:[DB06817 DB09105] DB06817|Raltegravir pol;UGT1A1 DB09105|Asfotase Alfa S1PR1 common genes common pathways 36170:[DB06817 DB09299] DB06817|Raltegravir pol;UGT1A1 DB09299|Tenofovir alafenamide pol;ABCB1 common genes pol common pathways GO:0042493| response to drug UGT1A1;ABCB1 36171:[DB06817 DB12130] DB06817|Raltegravir pol;UGT1A1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;UGT1A3;CYP2B6 GO:0008202| steroid metabolic process CYP2B6;CYP3A5;UGT1A1;CYP2C8;CYP2C19 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:1904224| UGT1A1;UGT1A3 GO:0042573| retinoic acid metabolic process UGT1A3;UGT1A1 GO:0008152| metabolic process UGT1A3;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19 GO:0052695| cellular glucuronidation UGT1A3;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A3 36172:[DB06817 DB00356] DB06817|Raltegravir pol;UGT1A1 DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug CYP2E1;CYP1A1;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;CYP1A1 GO:0010033| response to organic substance CYP1A2;CYP1A1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP2E1;CYP3A4;CYP2A6;CYP2D6;CYP1A2 GO:0017144| drug metabolic process CYP2A6;CYP3A4;CYP2D6;CYP1A2;UGT1A1;CYP1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP1A1;CYP2E1;UGT1A1;CYP2D6;CYP1A2;CYP3A4 GO:0001889| liver development CYP1A1;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;UGT1A1 36173:[DB06817 DB09039] DB06817|Raltegravir pol;UGT1A1 DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 36174:[DB06817 DB04620] DB06817|Raltegravir pol;UGT1A1 DB04620|Cycloleucine GRIN1 common genes common pathways GO:0045471| response to ethanol UGT1A1;GRIN1 36175:[DB06817 DB01332] DB06817|Raltegravir pol;UGT1A1 DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 36176:[DB06817 DB06016] DB06817|Raltegravir pol;UGT1A1 DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1;DRD3 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0042493| response to drug UGT1A1;HTR2B;HTR2A;DRD2;DRD3 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 36177:[DB06817 DB04519] DB06817|Raltegravir pol;UGT1A1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 36178:[DB06817 DB00322] DB06817|Raltegravir pol;UGT1A1 DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0008152| metabolic process TYMP;UGT1A1 GO:0045471| response to ethanol TYMS;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0008202| steroid metabolic process UGT1A1;CYP2C9 GO:0042493| response to drug UGT1A1;TYMS 36179:[DB06817 DB03664] DB06817|Raltegravir pol;UGT1A1 DB03664|UP5 CMPK1 common genes common pathways 36180:[DB06817 DB00191] DB06817|Raltegravir pol;UGT1A1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;SLC6A4;MAOB;SLC6A3;SLC6A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;MAOB;UGT1A1 GO:0010033| response to organic substance CYP1A2;SLC6A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0045471| response to ethanol SLC6A3;MAOB;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;SLC6A3;UGT1A1 36181:[DB06817 DB06650] DB06817|Raltegravir pol;UGT1A1 DB06650|Ofatumumab MS4A1 common genes common pathways 36182:[DB06817 DB00371] DB06817|Raltegravir pol;UGT1A1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug GABRG3;CYP2E1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP2C19 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;UGT1A1 36183:[DB06817 DB06684] DB06817|Raltegravir pol;UGT1A1 DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0042493| response to drug SLC6A4;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1 36184:[DB06817 DB00931] DB06817|Raltegravir pol;UGT1A1 DB00931|Metacycline ALB common genes common pathways 36185:[DB06817 DB05233] DB06817|Raltegravir pol;UGT1A1 DB05233|AP1081 ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 36186:[DB06817 DB00903] DB06817|Raltegravir pol;UGT1A1 DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0008152| metabolic process UGT1A1;GSTA2;GSTP1 GO:0045471| response to ethanol UGT1A1;GSTP1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:0042493| response to drug ATP1A1;UGT1A1 GO:0031100| organ regeneration GSTP1;UGT1A1 36187:[DB06817 DB07789] DB06817|Raltegravir pol;UGT1A1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways 36188:[DB06817 DB01089] DB06817|Raltegravir pol;UGT1A1 DB01089|Deserpidine SLC18A2 common genes common pathways 36189:[DB06817 DB13166] DB06817|Raltegravir pol;UGT1A1 DB13166|Zofenopril ACE common genes common pathways 36190:[DB06817 DB01223] DB06817|Raltegravir pol;UGT1A1 DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;UGT1A1;CYP1A2;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP2C19;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;HDAC2;UGT1A1;CYP2E1;PDE3A GO:0032496| response to lipopolysaccharide UGT1A1;HDAC2;CYP1A2 36191:[DB06817 DB00995] DB06817|Raltegravir pol;UGT1A1 DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways 36192:[DB06817 DB00108] DB06817|Raltegravir pol;UGT1A1 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0042493| response to drug ICAM1;UGT1A1 GO:0032496| response to lipopolysaccharide ICAM1;UGT1A1 GO:0045471| response to ethanol ICAM1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;ICAM1 36193:[DB06817 DB11858] DB06817|Raltegravir pol;UGT1A1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways 36194:[DB06817 DB14132] DB06817|Raltegravir pol;UGT1A1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1;ADORA2A GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 36195:[DB06817 DB09070] DB06817|Raltegravir pol;UGT1A1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process STS;UGT1A1;SULT1A1 GO:0008210| estrogen metabolic process UGT1A1;SULT1A1 GO:0008152| metabolic process HSD3B1;UGT1A1;HSD3B2;STS 36196:[DB06817 DB04905] DB06817|Raltegravir pol;UGT1A1 DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;CYP1A1;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0042493| response to drug UGT1A1;CYP1A1;ABCB1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1;CYP1A1 36197:[DB06817 DB00487] DB06817|Raltegravir pol;UGT1A1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 36198:[DB06817 DB13881] DB06817|Raltegravir pol;UGT1A1 DB13881|Tisagenlecleucel CD19 common genes common pathways 36199:[DB06817 DB05920] DB06817|Raltegravir pol;UGT1A1 DB05920|RTA 744 TOP2A common genes common pathways 36200:[DB06817 DB11397] DB06817|Raltegravir pol;UGT1A1 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0042493| response to drug BCHE;UGT1A1 36201:[DB06817 DB01589] DB06817|Raltegravir pol;UGT1A1 DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C9;CYP2B6;CYP3A4 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP2B6;CYP2C9;CYP3A4 GO:0042493| response to drug UGT1A1;GABRG3 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 36202:[DB06817 DB00104] DB06817|Raltegravir pol;UGT1A1 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;SSTR2;SSTR1 GO:0042594| response to starvation SSTR1;SSTR2;UGT1A1 GO:0007586| digestion SSTR1;SSTR2;UGT1A1 GO:0032496| response to lipopolysaccharide MPO;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;SSTR2;SSTR5 GO:0007584| response to nutrient SSTR1;SSTR2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36203:[DB06817 DB01064] DB06817|Raltegravir pol;UGT1A1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1;MAPK1 GO:0042493| response to drug UGT1A1;CYP1A1;SOD1 GO:0008202| steroid metabolic process UGT1A1;CYP1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1;SOD1 GO:0045471| response to ethanol UGT1A1;SOD1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 36204:[DB06817 DB06538] DB06817|Raltegravir pol;UGT1A1 DB06538|Robalzotan HTR1A common genes common pathways 36205:[DB06817 DB08190] DB06817|Raltegravir pol;UGT1A1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways 36206:[DB06817 DB09280] DB06817|Raltegravir pol;UGT1A1 DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP3A4;CYP2C19;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2B6;CYP2C9;CYP2C19;CYP2C8;UGT1A1 36207:[DB06817 DB01349] DB06817|Raltegravir pol;UGT1A1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36208:[DB06817 DB11774] DB06817|Raltegravir pol;UGT1A1 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 36209:[DB06817 DB01587] DB06817|Raltegravir pol;UGT1A1 DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;TSPO;UGT1A1 GO:0042493| response to drug ABCB1;TSPO;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36210:[DB06817 DB13500] DB06817|Raltegravir pol;UGT1A1 DB13500|Otilonium CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36211:[DB06817 DB09154] DB06817|Raltegravir pol;UGT1A1 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 36212:[DB06817 DB01231] DB06817|Raltegravir pol;UGT1A1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 36213:[DB06817 DB00511] DB06817|Raltegravir pol;UGT1A1 DB00511|Acetyldigitoxin ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;UGT1A1 36214:[DB06817 DB00917] DB06817|Raltegravir pol;UGT1A1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 GO:0042493| response to drug UGT1A1;ABCC4 GO:0032496| response to lipopolysaccharide PTGER2;PTGER4;PTGER1;UGT1A1 GO:0010033| response to organic substance UGT1A1;ABCC4 GO:0008202| steroid metabolic process CYP11A1;UGT1A1 36215:[DB06817 DB01583] DB06817|Raltegravir pol;UGT1A1 DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36216:[DB06817 DB07700] DB06817|Raltegravir pol;UGT1A1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0007584| response to nutrient AKR1C3;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;AKR1C3 36217:[DB06817 DB04951] DB06817|Raltegravir pol;UGT1A1 DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 36218:[DB06817 DB09230] DB06817|Raltegravir pol;UGT1A1 DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36219:[DB06817 DB04957] DB06817|Raltegravir pol;UGT1A1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0001889| liver development CYP1A1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1 GO:0042493| response to drug CYP1A1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP1A1;CYP3A5 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1 36220:[DB06817 DB05679] DB06817|Raltegravir pol;UGT1A1 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways GO:0010033| response to organic substance UGT1A1;IL12B 36221:[DB06817 DB13203] DB06817|Raltegravir pol;UGT1A1 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 36222:[DB06817 DB06479] DB06817|Raltegravir pol;UGT1A1 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 36223:[DB06817 DB11760] DB06817|Raltegravir pol;UGT1A1 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;ABCG2 36224:[DB06817 DB01456] DB06817|Raltegravir pol;UGT1A1 DB01456|5-androstenedione CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36225:[DB06817 DB02691] DB06817|Raltegravir pol;UGT1A1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways 36226:[DB06817 DB01399] DB06817|Raltegravir pol;UGT1A1 DB01399|Salsalate PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 36227:[DB06817 DB05514] DB06817|Raltegravir pol;UGT1A1 DB05514|Cobiprostone CLCN2 common genes common pathways 36228:[DB06817 DB01559] DB06817|Raltegravir pol;UGT1A1 DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2B6;CYP3A4 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2C19;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19 36229:[DB06817 DB09091] DB06817|Raltegravir pol;UGT1A1 DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0042493| response to drug HDAC2;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0032496| response to lipopolysaccharide HDAC2;UGT1A1 36230:[DB06817 DB04794] DB06817|Raltegravir pol;UGT1A1 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP3A4 GO:0045471| response to ethanol UGT1A1;CYP2E1 36231:[DB06817 DB12141] DB06817|Raltegravir pol;UGT1A1 DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0042493| response to drug UGT1A1;HTR2B;ABCG2;HTR2A;ABCB1;HTR1B;HTR2C GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0031100| organ regeneration UGT1A1;AXL;FLT3 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0045471| response to ethanol HTR1B;HTR3A;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36232:[DB06817 DB00769] DB06817|Raltegravir pol;UGT1A1 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 36233:[DB06817 DB05796] DB06817|Raltegravir pol;UGT1A1 DB05796|Daglutril MME common genes common pathways 36234:[DB06817 DB00078] DB06817|Raltegravir pol;UGT1A1 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 36235:[DB06817 DB09140] DB06817|Raltegravir pol;UGT1A1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways 36236:[DB06817 DB11614] DB06817|Raltegravir pol;UGT1A1 DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0032496| response to lipopolysaccharide PTAFR;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C9;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6;CYP2C9 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2D6 36237:[DB06817 DB01738] DB06817|Raltegravir pol;UGT1A1 DB01738|Phosphorylcolamine PRKCB common genes common pathways 36238:[DB06817 DB14064] DB06817|Raltegravir pol;UGT1A1 DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1 36239:[DB06817 DB06814] DB06817|Raltegravir pol;UGT1A1 DB06814|Protokylol ADRB2 common genes common pathways 36240:[DB06817 DB07919] DB06817|Raltegravir pol;UGT1A1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways 36241:[DB06817 DB06145] DB06817|Raltegravir pol;UGT1A1 DB06145|Spiramycin rplC;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36242:[DB06817 DB12118] DB06817|Raltegravir pol;UGT1A1 DB12118|Sotatercept ACVR2A common genes common pathways 36243:[DB06817 DB05542] DB06817|Raltegravir pol;UGT1A1 DB05542|Naronapride HTR4 common genes common pathways 36244:[DB06817 DB00580] DB06817|Raltegravir pol;UGT1A1 DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways GO:0052695| cellular glucuronidation UGT1A9;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9 GO:0045471| response to ethanol CA3;UGT1A1 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A9 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:1904224| UGT1A1;UGT1A9 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:0010033| response to organic substance CA2;UGT1A1;PTGS2 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP3A4;UGT1A9 36245:[DB06817 DB00592] DB06817|Raltegravir pol;UGT1A1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6 36246:[DB06817 DB13996] DB06817|Raltegravir pol;UGT1A1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0042493| response to drug UGT1A1;ATP1A1 36247:[DB06817 DB09227] DB06817|Raltegravir pol;UGT1A1 DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36248:[DB06817 DB00815] DB06817|Raltegravir pol;UGT1A1 DB00815|Sodium lauryl sulfate ALB common genes common pathways 36249:[DB06817 DB00839] DB06817|Raltegravir pol;UGT1A1 DB00839|Tolazamide ABCC8;KCNJ11;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0032496| response to lipopolysaccharide ABCC8;UGT1A1 GO:0042493| response to drug UGT1A1;ABCC8;KCNJ11 36250:[DB06817 DB00925] DB06817|Raltegravir pol;UGT1A1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0042493| response to drug UGT1A1;ADRA1A GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 36251:[DB06817 DB12418] DB06817|Raltegravir pol;UGT1A1 DB12418|Saccharin CA3 common genes common pathways GO:0045471| response to ethanol UGT1A1;CA3 36252:[DB06817 DB00449] DB06817|Raltegravir pol;UGT1A1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0042493| response to drug BCHE;ADRA1A;UGT1A1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE 36253:[DB06817 DB12061] DB06817|Raltegravir pol;UGT1A1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0045471| response to ethanol DRD3;DRD2;UGT1A1 GO:0042493| response to drug DRD3;DRD2;UGT1A1 36254:[DB06817 DB06215] DB06817|Raltegravir pol;UGT1A1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways 36255:[DB06817 DB09167] DB06817|Raltegravir pol;UGT1A1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP2C19;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug SLC6A4;CYP1A2;SLC6A2;UGT1A1;HTR2A;ADRA1A GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0007586| digestion CHRM3;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C9;CYP2D6;CYP1A2 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP1A2;UGT1A1;CYP2C19 36256:[DB06817 DB01973] DB06817|Raltegravir pol;UGT1A1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways GO:0007586| digestion PRSS2;UGT1A1 36257:[DB06817 DB09462] DB06817|Raltegravir pol;UGT1A1 DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0042493| response to drug UGT1A1;TGFBR2;CYP2E1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 GO:0010033| response to organic substance UGT1A1;TGFBR2;PPARD GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;TGFBR2 GO:0031100| organ regeneration GSTP1;TGFBR2;UGT1A1 GO:0045471| response to ethanol CYP2E1;GSTP1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1 GO:0008152| metabolic process GSTP1;NAGA;UGT1A1;ALDH1A1;PAPSS1 GO:0014070| response to organic cyclic compound TGFBR2;UGT1A1 GO:0007584| response to nutrient UGT1A1;TGFBR2 36258:[DB06817 DB02508] DB06817|Raltegravir pol;UGT1A1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0008202| steroid metabolic process UGT1A1;FDPS 36259:[DB06817 DB00319] DB06817|Raltegravir pol;UGT1A1 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways 36260:[DB06817 DB00393] DB06817|Raltegravir pol;UGT1A1 DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A5;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36261:[DB06817 DB00716] DB06817|Raltegravir pol;UGT1A1 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways 36262:[DB06817 DB01105] DB06817|Raltegravir pol;UGT1A1 DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug SLC6A3;UGT1A1;SLC6A2;SLC6A4 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0045471| response to ethanol SLC6A3;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36263:[DB06817 DB00030] DB06817|Raltegravir pol;UGT1A1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0071466| cellular response to xenobiotic stimulus RB1;UGT1A1 GO:0032870| cellular response to hormone stimulus IGFBP7;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;IGFBP7 GO:0008152| metabolic process CPE;PCSK1;UGT1A1;IDE 36264:[DB06817 DB01128] DB06817|Raltegravir pol;UGT1A1 DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP3A4;UGT1A1;CYP2C19 36265:[DB06817 DB13967] DB06817|Raltegravir pol;UGT1A1 DB13967|Patent Blue ALB common genes common pathways 36266:[DB06817 DB13884] DB06817|Raltegravir pol;UGT1A1 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways GO:0006953| acute-phase response F8;UGT1A1 36267:[DB06817 DB11995] DB06817|Raltegravir pol;UGT1A1 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C9 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP2C9 GO:0042493| response to drug ABCG2;UGT1A1;ABCB1 36268:[DB06817 DB06457] DB06817|Raltegravir pol;UGT1A1 DB06457|Tecastemizole KCNH2 common genes common pathways 36269:[DB06817 DB07117] DB06817|Raltegravir pol;UGT1A1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 36270:[DB06817 DB06371] DB06817|Raltegravir pol;UGT1A1 DB06371|Siplizumab CD2 common genes common pathways 36271:[DB06817 DB06602] DB06817|Raltegravir pol;UGT1A1 DB06602|Reslizumab IL5 common genes common pathways 36272:[DB06817 DB08059] DB06817|Raltegravir pol;UGT1A1 DB08059|Wortmannin PIK3CG;PLK1;PIK3R1;PIK3CA common genes common pathways GO:0001889| liver development UGT1A1;PIK3CA 36273:[DB06817 DB12874] DB06817|Raltegravir pol;UGT1A1 DB12874|Quizartinib FLT3 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0031100| organ regeneration FLT3;UGT1A1 36274:[DB06817 DB08794] DB06817|Raltegravir pol;UGT1A1 DB08794|Ethyl biscoumacetate GLUL;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36275:[DB06817 DB05750] DB06817|Raltegravir pol;UGT1A1 DB05750|AVE-1625 CNR1 common genes common pathways GO:0032496| response to lipopolysaccharide CNR1;UGT1A1 GO:0045471| response to ethanol UGT1A1;CNR1 GO:0007584| response to nutrient CNR1;UGT1A1 36276:[DB06817 DB00465] DB06817|Raltegravir pol;UGT1A1 DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36277:[DB06817 DB00720] DB06817|Raltegravir pol;UGT1A1 DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 36278:[DB06817 DB00573] DB06817|Raltegravir pol;UGT1A1 DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug PPARG;UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0014070| response to organic cyclic compound PPARG;UGT1A1;PTGS2 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36279:[DB06817 DB00120] DB06817|Raltegravir pol;UGT1A1 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0014070| response to organic cyclic compound TAT;UGT1A1;TH GO:0051384| response to glucocorticoid stimulus UGT1A1;TAT GO:0008152| metabolic process PAH;UGT1A1 GO:0045471| response to ethanol UGT1A1;TH GO:0048545| response to steroid hormone stimulus UGT1A1;TH GO:0042493| response to drug TH;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TH 36280:[DB06817 DB09329] DB06817|Raltegravir pol;UGT1A1 DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways 36281:[DB06817 DB00869] DB06817|Raltegravir pol;UGT1A1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0017144| drug metabolic process CYP2C9;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C9;CYP3A4 GO:0010033| response to organic substance UGT1A1;CA2 GO:0045471| response to ethanol CA3;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36282:[DB06817 DB06674] DB06817|Raltegravir pol;UGT1A1 DB06674|Golimumab TNF common genes common pathways GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0010033| response to organic substance UGT1A1;TNF 36283:[DB06817 DB11636] DB06817|Raltegravir pol;UGT1A1 DB11636|Nomegestrol CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36284:[DB06817 DB00998] DB06817|Raltegravir pol;UGT1A1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2;HTR1B GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0045471| response to ethanol UGT1A1;HTR1B GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 36285:[DB06817 DB00133] DB06817|Raltegravir pol;UGT1A1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0042493| response to drug UGT1A1;SRR GO:0032496| response to lipopolysaccharide UGT1A1;SRR GO:0014070| response to organic cyclic compound SRR;UGT1A1 GO:0051384| response to glucocorticoid stimulus AGXT;UGT1A1 GO:0008152| metabolic process UGT1A1;SPTLC2;CBS;SRR 36286:[DB06817 DB12089] DB06817|Raltegravir pol;UGT1A1 DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36287:[DB06817 DB07173] DB06817|Raltegravir pol;UGT1A1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 36288:[DB06817 DB09061] DB06817|Raltegravir pol;UGT1A1 DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0010033| response to organic substance CYP1A2;TRPA1;PPARG;SOD1;CYP1A1;PTGS2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;CYP2C9;CYP2D6;CYP3A4;CYP1B1;CYP3A7;CYP1A1;CYP17A1;CYP3A5;HMGCR;UGT1A1;CYP2C19 GO:0017144| drug metabolic process CYP1A1;UGT1A1;CYP2C19;CYP1A2;CYP2C9;CYP2D6;CYP3A4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug PPARG;TRPA1;CYP1A2;CAT;PTGS2;UGT1A1;SMPD1;ABCC1;ABCG2;SOD1;HTR2A;CYP1A1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR1;CNR2;CYP1A1;PTGS2;UGT1A1;IDO1 GO:0042594| response to starvation ACAT1;UGT1A1;PPARG GO:0014070| response to organic cyclic compound TRPA1;PPARG;CYP1A2;UGT1A1;PTGS2;AANAT;CYP1A1;ACAT1 GO:0007584| response to nutrient CNR1;PPARG;HMGCR;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0001889| liver development CYP1A1;ACAT1;UGT1A1 GO:0045471| response to ethanol UGT1A1;HMGCR;HTR3A;SOD1;OPRM1;CNR1;CAT GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;CYP3A4;CYP1A1;UGT1A1;CYP2C19 GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0008152| metabolic process UGT1A1;SMPD1;ACAT1 36289:[DB06817 DB00066] DB06817|Raltegravir pol;UGT1A1 DB00066|Follitropin FSHR common genes common pathways 36290:[DB06817 DB01873] DB06817|Raltegravir pol;UGT1A1 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36291:[DB06817 DB11595] DB06817|Raltegravir pol;UGT1A1 DB11595|Atezolizumab CD274 common genes common pathways 36292:[DB06817 DB01582] DB06817|Raltegravir pol;UGT1A1 DB01582|Sulfamethazine ALB common genes common pathways 36293:[DB06817 DB00397] DB06817|Raltegravir pol;UGT1A1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug DRD1;UGT1A1 36294:[DB06817 DB05012] DB06817|Raltegravir pol;UGT1A1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0042493| response to drug UGT1A1;SLC6A2 36295:[DB06817 DB13876] DB06817|Raltegravir pol;UGT1A1 DB13876|Brofaromine MAOA common genes common pathways 36296:[DB06817 DB09047] DB06817|Raltegravir pol;UGT1A1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways 36297:[DB06817 DB08922] DB06817|Raltegravir pol;UGT1A1 DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C8;UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP1A1;CYP2C8;UGT1A1;CYP2D6;CYP3A4 GO:0010033| response to organic substance CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1 GO:0042493| response to drug CYP1A1;DRD2;ADRA1A;HTR2A;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0045471| response to ethanol UGT1A1;DRD2 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP2D6;CYP3A4 36298:[DB06817 DB01576] DB06817|Raltegravir pol;UGT1A1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0045471| response to ethanol SLC6A3;UGT1A1 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0042493| response to drug SLC6A3;ADRA1A;SLC6A2;UGT1A1 36299:[DB06817 DB03615] DB06817|Raltegravir pol;UGT1A1 DB03615|Ribostamycin P4HB;rpsL common genes common pathways 36300:[DB06817 DB11560] DB06817|Raltegravir pol;UGT1A1 DB11560|Lesinurad SLC22A12;SLC22A11;CYP2C9 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;UGT1A1 GO:0042493| response to drug UGT1A1;SLC22A12 36301:[DB06817 DB13999] DB06817|Raltegravir pol;UGT1A1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0001889| liver development PROC;UGT1A1 GO:0042493| response to drug UGT1A1;CALR GO:0006953| acute-phase response UGT1A1;F2 GO:0010033| response to organic substance CALR;UGT1A1 36302:[DB06817 DB11598] DB06817|Raltegravir pol;UGT1A1 DB11598|Antithrombin III human SERPINC1 common genes common pathways GO:0007584| response to nutrient SERPINC1;UGT1A1 36303:[DB06817 DB11450] DB06817|Raltegravir pol;UGT1A1 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 36304:[DB06817 DB02236] DB06817|Raltegravir pol;UGT1A1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways GO:0010033| response to organic substance UGT1A1;GART GO:0008152| metabolic process GART;UGT1A1 36305:[DB06817 DB00270] DB06817|Raltegravir pol;UGT1A1 DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36306:[DB06817 DB00606] DB06817|Raltegravir pol;UGT1A1 DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways GO:0010033| response to organic substance CA2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 36307:[DB06817 DB08971] DB06817|Raltegravir pol;UGT1A1 DB08971|Fluocortolone CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36308:[DB06817 DB06691] DB06817|Raltegravir pol;UGT1A1 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 36309:[DB06817 DB13488] DB06817|Raltegravir pol;UGT1A1 DB13488|Bencyclane CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36310:[DB06817 DB08872] DB06817|Raltegravir pol;UGT1A1 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways 36311:[DB06817 DB06421] DB06817|Raltegravir pol;UGT1A1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways 36312:[DB06817 DB13133] DB06817|Raltegravir pol;UGT1A1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;COL1A1 GO:0042493| response to drug COL1A1;UGT1A1 GO:0006953| acute-phase response F8;UGT1A1 GO:0007584| response to nutrient UGT1A1;COL1A1 36313:[DB06817 DB00233] DB06817|Raltegravir pol;UGT1A1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0010033| response to organic substance CHUK;PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide CHUK;UGT1A1;PTGS2;MPO GO:0042493| response to drug UGT1A1;PTGS2;CHUK GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 36314:[DB06817 DB11606] DB06817|Raltegravir pol;UGT1A1 DB11606|Susoctocog alfa VWF common genes common pathways 36315:[DB06817 DB05155] DB06817|Raltegravir pol;UGT1A1 DB05155|CR665 OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1 36316:[DB06817 DB09080] DB06817|Raltegravir pol;UGT1A1 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2C9 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9 36317:[DB06817 DB00561] DB06817|Raltegravir pol;UGT1A1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0042493| response to drug UGT1A1;KCNK3 36318:[DB06817 DB11455] DB06817|Raltegravir pol;UGT1A1 DB11455|Robenacoxib PTGS2 common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 36319:[DB06817 DB01357] DB06817|Raltegravir pol;UGT1A1 DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP2C9;CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4;CYP2C9 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 36320:[DB06817 DB06654] DB06817|Raltegravir pol;UGT1A1 DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0045471| response to ethanol MAOB;CYP2E1;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;CYP2C19;UGT1A1 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0017144| drug metabolic process CYP1A1;CYP2E1;UGT1A1;CYP2C19;CYP2C9;CYP2B6;CYP2D6;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP1A1;CYP2E1;CYP2C19;UGT1A1;CYP2D6;CYP2B6;CYP2C9;CYP1A2;CYP3A4 GO:0010033| response to organic substance CYP1A2;CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide MAOB;CYP1A1;UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP1A1;MAOB;CYP2E1;UGT1A1;ABCG2 36321:[DB06817 DB01612] DB06817|Raltegravir pol;UGT1A1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0008152| metabolic process ALDH2;UGT1A1 36322:[DB06817 DB14518] DB06817|Raltegravir pol;UGT1A1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug UGT1A1;ATP1A1 36323:[DB06817 DB00867] DB06817|Raltegravir pol;UGT1A1 DB00867|Ritodrine ADRB2;PGD common genes common pathways 36324:[DB06817 DB00169] DB06817|Raltegravir pol;UGT1A1 DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1 GO:0042493| response to drug UGT1A1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2C8;UGT1A1;CYP2D6;CYP2B6;CYP11A1;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP2B6;CYP3A4;CYP1A1;CYP2C8;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1 36325:[DB06817 DB11901] DB06817|Raltegravir pol;UGT1A1 DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0017144| drug metabolic process CYP2C9;CYP3A4;UGT1A1;CYP2C8;CYP2C19 GO:0042493| response to drug ABCB1;GABRG3;ABCG2;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 36326:[DB06817 DB01586] DB06817|Raltegravir pol;UGT1A1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0042493| response to drug CYP2E1;UGT1A1;ABCC4;ABCC2 GO:0007586| digestion UGT1A1;AKR1C2 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1 GO:0010033| response to organic substance UGT1A1;ABCC4 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1;AKR1C2 36327:[DB06817 DB00880] DB06817|Raltegravir pol;UGT1A1 DB00880|Chlorothiazide SLC12A3;CA1;CA2;SLC22A6 common genes common pathways GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CA2 36328:[DB06817 DB05495] DB06817|Raltegravir pol;UGT1A1 DB05495|PG-530742 MMP9 common genes common pathways 36329:[DB06817 DB11113] DB06817|Raltegravir pol;UGT1A1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;PTGER4 36330:[DB06817 DB11633] DB06817|Raltegravir pol;UGT1A1 DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0045939| negative regulation of steroid metabolic process UGT1A1;UGT1A8 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9;UGT1A8 GO:0008152| metabolic process UGT1A9;UGT1A8;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6 GO:0051552| flavone metabolic process UGT1A9;UGT1A8;UGT1A1 GO:0052695| cellular glucuronidation UGT1A1;UGT1A9;UGT1A8 GO:0043086| negative regulation of catalytic activity UGT1A1;UGT1A8 GO:2001030| negative regulation of cellular glucuronidation UGT1A8;UGT1A9;UGT1A1 GO:0017144| drug metabolic process CYP2C8;CYP2C19;UGT1A1;UGT1A9;CYP3A4;CYP2D6;CYP2C9;CYP2B6;UGT1A8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP3A5;CYP3A4;CYP2B6;CYP2C9;UGT1A8;CYP2D6 GO:0010033| response to organic substance UGT1A1;KCNA5 GO:0052696| flavonoid glucuronidation UGT1A8;UGT1A9;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A8;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9;UGT1A8 GO:1904224| UGT1A9;UGT1A8;UGT1A1 GO:0042493| response to drug ABCB1;KCNJ11;ABCG2;UGT1A1 36331:[DB06817 DB13772] DB06817|Raltegravir pol;UGT1A1 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 36332:[DB06817 DB12267] DB06817|Raltegravir pol;UGT1A1 DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0031100| organ regeneration UGT1A1;FLT3 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP3A5;CYP2C8;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0042493| response to drug ABCG2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0001889| liver development UGT1A1;EGFR GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36333:[DB06817 DB03866] DB06817|Raltegravir pol;UGT1A1 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36334:[DB06817 DB04828] DB06817|Raltegravir pol;UGT1A1 DB04828|Zomepirac PTGDR2;CYP3A4;ALB common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36335:[DB06817 DB06077] DB06817|Raltegravir pol;UGT1A1 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:0045471| response to ethanol UGT1A1;DRD2 GO:0042493| response to drug UGT1A1;DRD2;HTR2A 36336:[DB06817 DB09074] DB06817|Raltegravir pol;UGT1A1 DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP2B6;CYP3A4;UGT1A1 36337:[DB06817 DB05116] DB06817|Raltegravir pol;UGT1A1 DB05116|Thymectacin TYMS common genes common pathways GO:0045471| response to ethanol UGT1A1;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0042493| response to drug UGT1A1;TYMS 36338:[DB06817 DB00411] DB06817|Raltegravir pol;UGT1A1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0008152| metabolic process PLA2G4A;UGT1A1 GO:0007586| digestion CHRM3;UGT1A1 36339:[DB06817 DB04860] DB06817|Raltegravir pol;UGT1A1 DB04860|Isatoribine TLR7 common genes common pathways 36340:[DB06817 DB00841] DB06817|Raltegravir pol;UGT1A1 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;COMT GO:0032496| response to lipopolysaccharide UGT1A1;COMT GO:0042493| response to drug COMT;UGT1A1;ADRA1A GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 36341:[DB06817 DB08228] DB06817|Raltegravir pol;UGT1A1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways 36342:[DB06817 DB05046] DB06817|Raltegravir pol;UGT1A1 DB05046|V1003 OPRK1;OPRM1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:0045471| response to ethanol OPRM1;OPRK1;UGT1A1 36343:[DB06817 DB11817] DB06817|Raltegravir pol;UGT1A1 DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0045471| response to ethanol PTK2B;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug UGT1A1;ABCG2;PTK2B GO:0032496| response to lipopolysaccharide JAK2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36344:[DB06817 DB01214] DB06817|Raltegravir pol;UGT1A1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 36345:[DB06817 DB08808] DB06817|Raltegravir pol;UGT1A1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 36346:[DB06817 DB14059] DB06817|Raltegravir pol;UGT1A1 DB14059|SC-236 PTGS2;NFKB2;NFKB1;RELA common genes common pathways GO:0001889| liver development RELA;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound RELA;UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide NFKB2;UGT1A1;PTGS2;RELA GO:0042493| response to drug PTGS2;UGT1A1;RELA GO:0010033| response to organic substance UGT1A1;PTGS2;RELA 36347:[DB06817 DB07517] DB06817|Raltegravir pol;UGT1A1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways 36348:[DB06817 DB01309] DB06817|Raltegravir pol;UGT1A1 DB01309|Insulin Glulisine INSR common genes common pathways 36349:[DB06817 DB00040] DB06817|Raltegravir pol;UGT1A1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways GO:0042594| response to starvation GCGR;UGT1A1 GO:0007584| response to nutrient UGT1A1;GCGR 36350:[DB06817 DB00309] DB06817|Raltegravir pol;UGT1A1 DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36351:[DB06817 DB06736] DB06817|Raltegravir pol;UGT1A1 DB06736|Aceclofenac PTGS2;PTGS1;CYP2C9 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0010033| response to organic substance PTGS2;UGT1A1 36352:[DB06817 DB11988] DB06817|Raltegravir pol;UGT1A1 DB11988|Ocrelizumab MS4A1 common genes common pathways 36353:[DB06817 DB05018] DB06817|Raltegravir pol;UGT1A1 DB05018|Migalastat GLA;UGT1A1 common genes UGT1A1 common pathways GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process GLA;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0042493| response to drug UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1 GO:0031100| organ regeneration UGT1A1 36354:[DB06817 DB00674] DB06817|Raltegravir pol;UGT1A1 DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0042493| response to drug BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0045471| response to ethanol UGT1A1;CHRNB2 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 36355:[DB06817 DB04881] DB06817|Raltegravir pol;UGT1A1 DB04881|Elacridar ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1;ABCG2 36356:[DB06817 DB03962] DB06817|Raltegravir pol;UGT1A1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways 36357:[DB06817 DB06153] DB06817|Raltegravir pol;UGT1A1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 GO:0042493| response to drug HTR2A;ADRA1A;HTR2B;UGT1A1;HTR2C;HTR1B GO:0045471| response to ethanol UGT1A1;HTR1B GO:0008152| metabolic process UGT1A1;UGT2B10 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 36358:[DB06817 DB08736] DB06817|Raltegravir pol;UGT1A1 DB08736|S,R-Warfarin alcohol ALB common genes common pathways 36359:[DB06817 DB00911] DB06817|Raltegravir pol;UGT1A1 DB00911|Tinidazole CYP3A4;ABCB11 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36360:[DB06817 DB09129] DB06817|Raltegravir pol;UGT1A1 DB09129|Chromic chloride INSR common genes common pathways 36361:[DB06817 DB06796] DB06817|Raltegravir pol;UGT1A1 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways 36362:[DB06817 DB06533] DB06817|Raltegravir pol;UGT1A1 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance PPARG;UGT1A1 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug UGT1A1;PPARG GO:0042594| response to starvation PPARG;UGT1A1 36363:[DB06817 DB06472] DB06817|Raltegravir pol;UGT1A1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways 36364:[DB06817 DB00384] DB06817|Raltegravir pol;UGT1A1 DB00384|Triamterene SCNN1G;SCNN1A;SCNN1B;SCNN1D;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 36365:[DB06817 DB00906] DB06817|Raltegravir pol;UGT1A1 DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes UGT1A1 common pathways GO:0042594| response to starvation UGT1A1 GO:0007586| digestion UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0042493| response to drug UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound SLC6A1;UGT1A1 36366:[DB06817 DB00743] DB06817|Raltegravir pol;UGT1A1 DB00743|Gadobenic acid ALB common genes common pathways 36367:[DB06817 DB08811] DB06817|Raltegravir pol;UGT1A1 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0008152| metabolic process UGT1A1;PDE2A;PDE10A GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug UGT1A1;PDE3A GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36368:[DB06817 DB01092] DB06817|Raltegravir pol;UGT1A1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0042493| response to drug CYP1A1;ATP1A1;UGT1A1;ATP1A3 GO:0008202| steroid metabolic process CYP1A1;UGT1A1 GO:0017144| drug metabolic process CYP1A1;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1 36369:[DB06817 DB01077] DB06817|Raltegravir pol;UGT1A1 DB01077|Etidronic acid PTPRS;ATP6V1A common genes common pathways 36370:[DB06817 DB03255] DB06817|Raltegravir pol;UGT1A1 DB03255|Phenol cobT;ALB common genes common pathways 36371:[DB06817 DB05487] DB06817|Raltegravir pol;UGT1A1 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0032496| response to lipopolysaccharide NFKB2;UGT1A1 36372:[DB06817 DB00942] DB06817|Raltegravir pol;UGT1A1 DB00942|Cycrimine CHRM1 common genes common pathways 36373:[DB06817 DB03861] DB06817|Raltegravir pol;UGT1A1 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways GO:0008152| metabolic process UGT1A1;HEXB 36374:[DB06817 DB04816] DB06817|Raltegravir pol;UGT1A1 DB04816|Dantron ALB common genes common pathways 36375:[DB06817 DB04846] DB06817|Raltegravir pol;UGT1A1 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 36376:[DB06817 DB01698] DB06817|Raltegravir pol;UGT1A1 DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;AKR1C3;CYP2C8;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CBR1;CYP3A4 GO:0007584| response to nutrient UGT1A1;AKR1C3 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36377:[DB06817 DB01791] DB06817|Raltegravir pol;UGT1A1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways 36378:[DB06817 DB00896] DB06817|Raltegravir pol;UGT1A1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 36379:[DB06817 DB00967] DB06817|Raltegravir pol;UGT1A1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2;ABCB1 GO:0008202| steroid metabolic process CYP1A2;CYP2C9;CYP2D6;UGT1A1;CYP2C19 GO:0017144| drug metabolic process CYP1A2;CYP2C9;CYP2D6;UGT1A1;CYP2C19 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 36380:[DB06817 DB06789] DB06817|Raltegravir pol;UGT1A1 DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;UGT1A1;CYP3A5 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C19 36381:[DB06817 DB00485] DB06817|Raltegravir pol;UGT1A1 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0007586| digestion SLC15A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36382:[DB06817 DB12070] DB06817|Raltegravir pol;UGT1A1 DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes UGT1A1 common pathways GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A3 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0052695| cellular glucuronidation UGT1A1;UGT1A3 GO:0006789| bilirubin conjugation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A3 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP3A4 GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2C19;CYP3A4;UGT1A3;CYP2B6;CYP2C9;CYP2D6 GO:0031100| organ regeneration UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP2C8;CYP2C19;UGT1A1;CYP2D6;CYP2C9;CYP2B6;CYP3A4 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0042493| response to drug ABCG2;UGT1A1;ABCC2;ABCB1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:1904224| UGT1A1;UGT1A3 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1 36383:[DB06817 DB06705] DB06817|Raltegravir pol;UGT1A1 DB06705|Gadofosveset trisodium ALB common genes common pathways 36384:[DB06817 DB05708] DB06817|Raltegravir pol;UGT1A1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;CYP2E1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2E1;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 36385:[DB06817 DB00383] DB06817|Raltegravir pol;UGT1A1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 36386:[DB06817 DB00616] DB06817|Raltegravir pol;UGT1A1 DB00616|Candoxatril MME;ACE common genes common pathways 36387:[DB06817 DB00180] DB06817|Raltegravir pol;UGT1A1 DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36388:[DB06817 DB08960] DB06817|Raltegravir pol;UGT1A1 DB08960|Hexamethonium CHRNA2 common genes common pathways 36389:[DB06817 DB06147] DB06817|Raltegravir pol;UGT1A1 DB06147|Sulfathiazole CYP19A1 common genes common pathways 36390:[DB06817 DB13136] DB06817|Raltegravir pol;UGT1A1 DB13136|Fluindione CYP2C9;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2C9 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP3A4 36391:[DB06817 DB06716] DB06817|Raltegravir pol;UGT1A1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0008152| metabolic process ALPL;UGT1A1 GO:0051384| response to glucocorticoid stimulus ALPL;UGT1A1 GO:0032496| response to lipopolysaccharide ALPL;UGT1A1 36392:[DB06817 DB11855] DB06817|Raltegravir pol;UGT1A1 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0007586| digestion CHRM3;UGT1A1 GO:0042493| response to drug UGT1A1;ABCG2;ABCB1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 36393:[DB06817 DB12515] DB06817|Raltegravir pol;UGT1A1 DB12515|9-aminocamptothecin CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36394:[DB06817 DB01497] DB06817|Raltegravir pol;UGT1A1 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 36395:[DB06817 DB05253] DB06817|Raltegravir pol;UGT1A1 DB05253|Proellex PGR common genes common pathways 36396:[DB06817 DB00523] DB06817|Raltegravir pol;UGT1A1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0042573| retinoic acid metabolic process CRABP2;UGT1A1 GO:0045471| response to ethanol UGT1A1;RARA GO:0001889| liver development RARA;UGT1A1 36397:[DB06817 DB00259] DB06817|Raltegravir pol;UGT1A1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1;CYP2C19;CYP2E1 GO:0017144| drug metabolic process CYP2E1;CYP2C19;UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1;CYP2E1 GO:0042493| response to drug UGT1A1;CYP2E1 36398:[DB06817 DB00306] DB06817|Raltegravir pol;UGT1A1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 36399:[DB06817 DB00288] DB06817|Raltegravir pol;UGT1A1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;UGT1A1;NR3C1 GO:0042493| response to drug ANXA1;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;ANXA1 GO:0014070| response to organic cyclic compound UGT1A1;ANXA1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36400:[DB06817 DB00279] DB06817|Raltegravir pol;UGT1A1 DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug UGT1A1;ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36401:[DB06817 DB04975] DB06817|Raltegravir pol;UGT1A1 DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP3A4;CYP2B6 GO:0008202| steroid metabolic process CYP1A1;UGT1A1;CYP2B6;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP1A1 36402:[DB06817 DB08626] DB06817|Raltegravir pol;UGT1A1 DB08626|Thiorphan MME common genes common pathways 36403:[DB06817 DB05115] DB06817|Raltegravir pol;UGT1A1 DB05115|NN344 INSR common genes common pathways 36404:[DB06817 DB06042] DB06817|Raltegravir pol;UGT1A1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways 36405:[DB06817 DB14724] DB06817|Raltegravir pol;UGT1A1 DB14724|Emapalumab IFNG common genes common pathways 36406:[DB06817 DB03425] DB06817|Raltegravir pol;UGT1A1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways 36407:[DB06817 DB00750] DB06817|Raltegravir pol;UGT1A1 DB00750|Prilocaine SCN5A common genes common pathways 36408:[DB06817 DB05849] DB06817|Raltegravir pol;UGT1A1 DB05849|NCX 950 ADRB2 common genes common pathways 36409:[DB06817 DB04445] DB06817|Raltegravir pol;UGT1A1 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0007586| digestion SULT2A1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;SULT2A1 36410:[DB06817 DB12923] DB06817|Raltegravir pol;UGT1A1 DB12923|Gallopamil CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36411:[DB06817 DB04934] DB06817|Raltegravir pol;UGT1A1 DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36412:[DB06817 DB00751] DB06817|Raltegravir pol;UGT1A1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP2B6;CYP3A4 GO:0017144| drug metabolic process CYP2B6;CYP2D6;CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;ADRA1A;HTR2A;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 36413:[DB06817 DB08972] DB06817|Raltegravir pol;UGT1A1 DB08972|Flumequine CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 36414:[DB06817 DB00765] DB06817|Raltegravir pol;UGT1A1 DB00765|Metyrosine TH common genes common pathways GO:0048545| response to steroid hormone stimulus UGT1A1;TH GO:0032496| response to lipopolysaccharide TH;UGT1A1 GO:0042493| response to drug UGT1A1;TH GO:0014070| response to organic cyclic compound TH;UGT1A1 GO:0045471| response to ethanol UGT1A1;TH 36415:[DB06817 DB05824] DB06817|Raltegravir pol;UGT1A1 DB05824|CNS-5161 GRIN1 common genes common pathways GO:0045471| response to ethanol GRIN1;UGT1A1 36416:[DB06817 DB00805] DB06817|Raltegravir pol;UGT1A1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0042493| response to drug DRD2;DRD1;HTR2A;HTR2B;UGT1A1;HTR2C;SLC6A4 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0045471| response to ethanol DRD2;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 36417:[DB06817 DB06201] DB06817|Raltegravir pol;UGT1A1 DB06201|Rufinamide GRM5;SCN9A;CES1;CYP2E1;CYP3A4;ALB common genes common pathways GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP3A4 GO:0008152| metabolic process UGT1A1;CES1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP2E1;UGT1A1;CYP3A4 GO:0042493| response to drug UGT1A1;CYP2E1 36418:[DB06817 DB00374] DB06817|Raltegravir pol;UGT1A1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0010033| response to organic substance PPARD;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0008202| steroid metabolic process UGT1A1;CYP2C9 GO:0032496| response to lipopolysaccharide PTGIR;UGT1A1 36419:[DB06817 DB05875] DB06817|Raltegravir pol;UGT1A1 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes common pathways GO:0007584| response to nutrient BCHE;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1;PTGS2 GO:0042493| response to drug BCHE;PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 36420:[DB06817 DB04880] DB06817|Raltegravir pol;UGT1A1 DB04880|Enoximone PDE3A common genes common pathways GO:0042493| response to drug UGT1A1;PDE3A 36421:[DB06817 DB12007] DB06817|Raltegravir pol;UGT1A1 DB12007|Isoflavone PPARA;PPARG common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0007584| response to nutrient UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0042493| response to drug PPARG;UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG 36422:[DB06817 DB00947] DB06817|Raltegravir pol;UGT1A1 DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes UGT1A1 common pathways GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0042493| response to drug UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 36423:[DB06817 DB08899] DB06817|Raltegravir pol;UGT1A1 DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A5;CYP3A4;CYP2C9;CYP2B6;CYP2D6 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C9;CYP2B6;CYP2C19;CYP2C8;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP3A4 36424:[DB06817 DB01134] DB06817|Raltegravir pol;UGT1A1 DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36425:[DB06817 DB00527] DB06817|Raltegravir pol;UGT1A1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0042493| response to drug BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE 36426:[DB06817 DB00253] DB06817|Raltegravir pol;UGT1A1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 36427:[DB06817 DB01323] DB06817|Raltegravir pol;UGT1A1 DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2D6 GO:0042493| response to drug ABCB1;UGT1A1 36428:[DB06817 DB06781] DB06817|Raltegravir pol;UGT1A1 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 36429:[DB06817 DB00939] DB06817|Raltegravir pol;UGT1A1 DB00939|Meclofenamic acid PTGS1;PTGS2;ALOX5;KCNQ2;KCNQ3;SLC22A6;SLCO1C1 common genes common pathways GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36430:[DB06817 DB01892] DB06817|Raltegravir pol;UGT1A1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0008202| steroid metabolic process NR1I2;UGT1A1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1 GO:0042493| response to drug ABCC2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 36431:[DB06817 DB06823] DB06817|Raltegravir pol;UGT1A1 DB06823|Tiopronin MPO common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;MPO 36432:[DB06817 DB06804] DB06817|Raltegravir pol;UGT1A1 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 36433:[DB06817 DB12131] DB06817|Raltegravir pol;UGT1A1 DB12131|Vinpocetine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36434:[DB06817 DB00826] DB06817|Raltegravir pol;UGT1A1 DB00826|Natamycin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36435:[DB06817 DB04820] DB06817|Raltegravir pol;UGT1A1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;UGT1A1;COMT GO:0042493| response to drug UGT1A1;MAOB;COMT GO:0008210| estrogen metabolic process COMT;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0045471| response to ethanol UGT1A1;MAOB GO:0014070| response to organic cyclic compound COMT;UGT1A1 36436:[DB06817 DB06754] DB06817|Raltegravir pol;UGT1A1 DB06754|Danaparoid SERPINC1 common genes common pathways GO:0007584| response to nutrient UGT1A1;SERPINC1 36437:[DB06817 DB13346] DB06817|Raltegravir pol;UGT1A1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0010033| response to organic substance HDAC6;PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 36438:[DB06817 DB11742] DB06817|Raltegravir pol;UGT1A1 DB11742|Ebastine CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36439:[DB06817 DB04920] DB06817|Raltegravir pol;UGT1A1 DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1;CYP2E1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 GO:0042493| response to drug BCHE;UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4;CYP2D6;CYP2C9 36440:[DB06817 DB06742] DB06817|Raltegravir pol;UGT1A1 DB06742|Ambroxol CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36441:[DB06817 DB03546] DB06817|Raltegravir pol;UGT1A1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways GO:0008152| metabolic process UGT1A1;GART GO:0010033| response to organic substance UGT1A1;GART 36442:[DB06817 DB00325] DB06817|Raltegravir pol;UGT1A1 DB00325|Nitroprusside NPR1;CYP1A1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP1A1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 36443:[DB06817 DB13931] DB06817|Raltegravir pol;UGT1A1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways 36444:[DB06817 DB00179] DB06817|Raltegravir pol;UGT1A1 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways 36445:[DB06817 DB07879] DB06817|Raltegravir pol;UGT1A1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0042493| response to drug HDAC4;UGT1A1 36446:[DB06817 DB07453] DB06817|Raltegravir pol;UGT1A1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 36447:[DB06817 DB00257] DB06817|Raltegravir pol;UGT1A1 DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1;CYP11B1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1;CYP2E1 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0017144| drug metabolic process CYP2C9;CYP2B6;CYP2D6;CYP3A4;CYP2A6;CYP2E1;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;NR1I2;CYP2D6;CYP11A1;CYP3A4;CYP2A6;CYP3A7;CYP11B1;CYP2E1;UGT1A1;CYP2C8 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1;ABCB1;ABCC2 36448:[DB06817 DB03747] DB06817|Raltegravir pol;UGT1A1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways GO:0008152| metabolic process HEXB;UGT1A1 36449:[DB06817 DB06819] DB06817|Raltegravir pol;UGT1A1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process CYP2D6;UGT1A1 36450:[DB06817 DB08865] DB06817|Raltegravir pol;UGT1A1 DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP3A5;CYP3A7;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2B6 GO:0042493| response to drug UGT1A1;ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36451:[DB06817 DB00155] DB06817|Raltegravir pol;UGT1A1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0001889| liver development UGT1A1;OTC GO:0042493| response to drug OTC;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;NOS2 36452:[DB06817 DB08813] DB06817|Raltegravir pol;UGT1A1 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0042493| response to drug FOS;MYC;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;FOS;SELP GO:0014070| response to organic cyclic compound UGT1A1;FOS GO:0007584| response to nutrient SERPINC1;UGT1A1 GO:0032870| cellular response to hormone stimulus FOS;UGT1A1 36453:[DB06817 DB09082] DB06817|Raltegravir pol;UGT1A1 DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36454:[DB06817 DB00055] DB06817|Raltegravir pol;UGT1A1 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways GO:0032496| response to lipopolysaccharide THBD;UGT1A1;PF4 GO:0006953| acute-phase response F8;F2;UGT1A1 36455:[DB06817 DB01359] DB06817|Raltegravir pol;UGT1A1 DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0042493| response to drug HTR1B;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0045471| response to ethanol HTR1B;UGT1A1 36456:[DB06817 DB07992] DB06817|Raltegravir pol;UGT1A1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways 36457:[DB06817 DB04884] DB06817|Raltegravir pol;UGT1A1 DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways GO:0045471| response to ethanol HTR1B;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0042493| response to drug UGT1A1;HTR2C;HTR1B GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2D6 36458:[DB06817 DB13981] DB06817|Raltegravir pol;UGT1A1 DB13981|Nomegestrol acetate CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36459:[DB06817 DB09017] DB06817|Raltegravir pol;UGT1A1 DB09017|Brotizolam CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36460:[DB06817 DB09121] DB06817|Raltegravir pol;UGT1A1 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug ADCY1;UGT1A1 36461:[DB06817 DB03010] DB06817|Raltegravir pol;UGT1A1 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36462:[DB06817 DB00032] DB06817|Raltegravir pol;UGT1A1 DB00032|Menotropins FSHR;LHCGR common genes common pathways 36463:[DB06817 DB00323] DB06817|Raltegravir pol;UGT1A1 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways GO:0014070| response to organic cyclic compound COMT;UGT1A1 GO:0042493| response to drug COMT;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;COMT GO:0032496| response to lipopolysaccharide UGT1A1;COMT GO:0008202| steroid metabolic process UGT1A1;CYP2C9 GO:0017144| drug metabolic process CYP2C9;UGT1A1 36464:[DB06817 DB00924] DB06817|Raltegravir pol;UGT1A1 DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes UGT1A1 common pathways GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2;CYP2D6 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0042493| response to drug HTR2A;UGT1A1;CYP1A2 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:1904224| UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP1A2;CYP2D6 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP1A2;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1 36465:[DB06817 DB13158] DB06817|Raltegravir pol;UGT1A1 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36466:[DB06817 DB05416] DB06817|Raltegravir pol;UGT1A1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0010033| response to organic substance PPARD;UGT1A1 36467:[DB06817 DB06433] DB06817|Raltegravir pol;UGT1A1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0008152| metabolic process TYMP;RRM1;UGT1A1 36468:[DB06817 DB00548] DB06817|Raltegravir pol;UGT1A1 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0008152| metabolic process TYR;UGT1A1 GO:0014070| response to organic cyclic compound SRD5A2;UGT1A1 GO:0007586| digestion AKR1D1;UGT1A1 GO:0042493| response to drug SRD5A2;UGT1A1 GO:0048545| response to steroid hormone stimulus SRD5A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;SRD5A2;AKR1D1 GO:0010033| response to organic substance SRD5A2;UGT1A1 36469:[DB06817 DB06727] DB06817|Raltegravir pol;UGT1A1 DB06727|Sparteine CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 36470:[DB06817 DB00406] DB06817|Raltegravir pol;UGT1A1 DB00406|Gentian violet cation SLC22A1 common genes common pathways 36471:[DB06817 DB09401] DB06817|Raltegravir pol;UGT1A1 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0042493| response to drug BCL2;UGT1A1 GO:0051384| response to glucocorticoid stimulus BCL2;UGT1A1 36472:[DB06817 DB05309] DB06817|Raltegravir pol;UGT1A1 DB05309|TP-508 FGF4 common genes common pathways 36473:[DB06817 DB12212] DB06817|Raltegravir pol;UGT1A1 DB12212|Landiolol CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 36474:[DB06817 DB05050] DB06817|Raltegravir pol;UGT1A1 DB05050|ADL5859 OPRD1 common genes common pathways 36475:[DB06817 DB07348] DB06817|Raltegravir pol;UGT1A1 DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36476:[DB06817 DB01581] DB06817|Raltegravir pol;UGT1A1 DB01581|Sulfamerazine ALB common genes common pathways 36477:[DB06817 DB07246] DB06817|Raltegravir pol;UGT1A1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 36478:[DB06817 DB13385] DB06817|Raltegravir pol;UGT1A1 DB13385|Dihydroergocryptine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36479:[DB06817 DB08810] DB06817|Raltegravir pol;UGT1A1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0042493| response to drug UGT1A1;HTR2A 36480:[DB06817 DB01000] DB06817|Raltegravir pol;UGT1A1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 36481:[DB06817 DB06154] DB06817|Raltegravir pol;UGT1A1 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways GO:0008152| metabolic process UGT1A1;ALDH2 36482:[DB06817 DB06162] DB06817|Raltegravir pol;UGT1A1 DB06162|Lumiliximab FCER2 common genes common pathways 36483:[DB06817 DB06268] DB06817|Raltegravir pol;UGT1A1 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;EDNRB GO:0032496| response to lipopolysaccharide EDNRB;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2C9 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2C9 36484:[DB06817 DB09234] DB06817|Raltegravir pol;UGT1A1 DB09234|Darodipine CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36485:[DB06817 DB08916] DB06817|Raltegravir pol;UGT1A1 DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0001889| liver development UGT1A1;EGFR GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1 GO:0042493| response to drug ABCG2;UGT1A1;ABCB1 36486:[DB06817 DB05787] DB06817|Raltegravir pol;UGT1A1 DB05787|LM-609 ITGB3 common genes common pathways 36487:[DB06817 DB08884] DB06817|Raltegravir pol;UGT1A1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0010033| response to organic substance UGT1A1;ABCC4 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0042493| response to drug UGT1A1;ABCC4;ABCC2 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 36488:[DB06817 DB05458] DB06817|Raltegravir pol;UGT1A1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways GO:0045471| response to ethanol CHRNB2;UGT1A1 36489:[DB06817 DB01437] DB06817|Raltegravir pol;UGT1A1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0042493| response to drug UGT1A1;GABRG3 GO:0008202| steroid metabolic process CYP2D6;CYP11A1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 36490:[DB06817 DB06778] DB06817|Raltegravir pol;UGT1A1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes common pathways GO:0010033| response to organic substance SOD1;UGT1A1 GO:0048545| response to steroid hormone stimulus LOX;MAOB;UGT1A1 GO:0042493| response to drug MAOB;SOD1;UGT1A1;LOX GO:0032496| response to lipopolysaccharide MAOB;UGT1A1 GO:0045471| response to ethanol UGT1A1;MAOB;SOD1 GO:0008152| metabolic process PAH;UGT1A1;TYR 36491:[DB06817 DB06204] DB06817|Raltegravir pol;UGT1A1 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0052695| cellular glucuronidation UGT2B7;UGT1A1;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0008152| metabolic process UGT2B7;UGT1A1;UGT1A9 GO:0045471| response to ethanol OPRK1;OPRM1;HTR3A;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2D6 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C9;CYP2D6;UGT1A9 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;UGT2B7;UGT1A1;CYP2C19 GO:0042493| response to drug UGT1A1;SLC6A2;SLC6A4 GO:1904224| UGT1A1;UGT1A9 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 36492:[DB06817 DB09028] DB06817|Raltegravir pol;UGT1A1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0045471| response to ethanol UGT1A1;CHRNB2 36493:[DB06817 DB00744] DB06817|Raltegravir pol;UGT1A1 DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0052695| cellular glucuronidation UGT1A1;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9 GO:0008152| metabolic process UGT1A9;UGT1A1 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1 GO:1904224| UGT1A1;UGT1A9 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP1A2;UGT1A9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP1A2;UGT1A1 36494:[DB06817 DB00452] DB06817|Raltegravir pol;UGT1A1 DB00452|Framycetin rpsL;CXCR4 common genes common pathways 36495:[DB06817 DB00937] DB06817|Raltegravir pol;UGT1A1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0045471| response to ethanol UGT1A1;SLC6A3 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 GO:0042493| response to drug SLC6A3;UGT1A1;SLC6A2 36496:[DB06817 DB13191] DB06817|Raltegravir pol;UGT1A1 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways 36497:[DB06817 DB06186] DB06817|Raltegravir pol;UGT1A1 DB06186|Ipilimumab CTLA4 common genes common pathways 36498:[DB06817 DB00247] DB06817|Raltegravir pol;UGT1A1 DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug HTR1B;HTR2C;UGT1A1;HTR2B;HTR2A GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0045471| response to ethanol UGT1A1;HTR1B 36499:[DB06817 DB03515] DB06817|Raltegravir pol;UGT1A1 DB03515|Equilenin CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36500:[DB06817 DB05260] DB06817|Raltegravir pol;UGT1A1 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0006953| acute-phase response TFR2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;IL1B 36501:[DB06817 DB04977] DB06817|Raltegravir pol;UGT1A1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP3A4;CYP2A6;UGT1A1;CYP2E1 GO:0042493| response to drug UGT1A1;CYP2E1 36502:[DB06817 DB01239] DB06817|Raltegravir pol;UGT1A1 DB01239|Chlorprothixene DRD2;DRD1;DRD3;HTR2A;HTR2B;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ABCB1 common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1;DRD3 GO:0007586| digestion UGT1A1;CHRM3 GO:0042493| response to drug HTR2B;UGT1A1;DRD2;DRD1;HTR2A;ABCB1;DRD3;HTR2C 36503:[DB06817 DB00724] DB06817|Raltegravir pol;UGT1A1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36504:[DB06817 DB06271] DB06817|Raltegravir pol;UGT1A1 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways GO:0007584| response to nutrient UGT1A1;SERPINC1 36505:[DB06817 DB13956] DB06817|Raltegravir pol;UGT1A1 DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes UGT1A1 common pathways GO:0001889| liver development CYP1A1;UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP1A1;CYP3A4;CYP1A2 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1;NCOA2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;CYP1A2 GO:0007586| digestion FABP2;UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0042493| response to drug ABCG2;UGT1A1;BECN1;CYP1A1;ABCB1;CYP1A2 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR2;ESR1;GPER1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP1B1;CYP3A4;CYP2C9;NR1I2;CYP1A2 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP1A2;UGT1A1;CYP2C19;CYP2C8;CYP1A1 GO:0031100| organ regeneration UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1 36506:[DB06817 DB00875] DB06817|Raltegravir pol;UGT1A1 DB00875|Flupentixol DRD2;HTR2A;DRD1;ADRA1A;CHRM1;DDC;ABCB1 common genes common pathways GO:0045471| response to ethanol UGT1A1;DRD2 GO:0042493| response to drug ABCB1;UGT1A1;ADRA1A;DRD2;HTR2A;DRD1 36507:[DB06817 DB01193] DB06817|Raltegravir pol;UGT1A1 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 36508:[DB06817 DB03552] DB06817|Raltegravir pol;UGT1A1 DB03552|3-Tyrosine TH common genes common pathways GO:0048545| response to steroid hormone stimulus TH;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;TH GO:0042493| response to drug UGT1A1;TH GO:0014070| response to organic cyclic compound UGT1A1;TH GO:0045471| response to ethanol TH;UGT1A1 36509:[DB06817 DB00171] DB06817|Raltegravir pol;UGT1A1 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes common pathways GO:0008202| steroid metabolic process UGT1A1;ABCA1;PRKAA1 GO:0017144| drug metabolic process UGT1A1;NT5C2 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0010033| response to organic substance AKT1;UGT1A1;ABCC4;ABCG1;ACSL1 GO:0032496| response to lipopolysaccharide ABCC8;UGT1A1;ABCC2 GO:0042493| response to drug ACSL1;ABCC4;ADCY1;ABCB1;ABCC2;ABCA1;ABCC6;ABCC1;UGT1A1;ABCC9;ABCC8 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1;ASNS GO:0014070| response to organic cyclic compound ACSL1;ABCC4;UGT1A1 GO:0007584| response to nutrient UGT1A1;ACSL1;APAF1;ABCA1 GO:0001889| liver development ASNS;UGT1A1;PIK3CA GO:0008152| metabolic process UGT1A1;NT5C2;ACSL1;ACSS2;ACSS1 GO:0071361| cellular response to ethanol PRKAA1;UGT1A1 36510:[DB06817 DB05766] DB06817|Raltegravir pol;UGT1A1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1;DRD3 GO:0042493| response to drug DRD3;UGT1A1;DRD2 36511:[DB06817 DB08883] DB06817|Raltegravir pol;UGT1A1 DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP2B6;CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;CYP1A2;UGT1A1;CYP3A5 36512:[DB06817 DB00352] DB06817|Raltegravir pol;UGT1A1 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0010033| response to organic substance UGT1A1;ABCC4 GO:0042493| response to drug UGT1A1;ABCC4 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 36513:[DB06817 DB09066] DB06817|Raltegravir pol;UGT1A1 DB09066|Corifollitropin alfa FSHR common genes common pathways 36514:[DB06817 DB06738] DB06817|Raltegravir pol;UGT1A1 DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0008152| metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0045471| response to ethanol OPRM1;GRIN2B;GRIN2A;OPRK1;UGT1A1;GRIN3A;GRIN1 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A9;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:1904224| UGT1A1;UGT1A9 GO:0042493| response to drug GRIN2A;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4;UGT1A9;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;UGT1A1;CYP3A4;CYP2B6;CYP2C9 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 36515:[DB06817 DB09215] DB06817|Raltegravir pol;UGT1A1 DB09215|Droxicam PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 36516:[DB06817 DB05223] DB06817|Raltegravir pol;UGT1A1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0010033| response to organic substance UGT1A1;HDAC6 GO:0032496| response to lipopolysaccharide HDAC1;UGT1A1;HDAC2 GO:0042493| response to drug HDAC1;UGT1A1;HDAC2 36517:[DB06817 DB12698] DB06817|Raltegravir pol;UGT1A1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways 36518:[DB06817 DB01597] DB06817|Raltegravir pol;UGT1A1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways 36519:[DB06817 DB00031] DB06817|Raltegravir pol;UGT1A1 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0043086| negative regulation of catalytic activity UGT1A1;ANXA2 GO:0010033| response to organic substance CALR;UGT1A1 GO:0042493| response to drug CALR;UGT1A1 36520:[DB06817 DB00642] DB06817|Raltegravir pol;UGT1A1 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0008152| metabolic process UGT1A1;ATIC;GART GO:0045471| response to ethanol TYMS;UGT1A1 GO:0031100| organ regeneration UGT1A1;ATIC GO:0010033| response to organic substance GART;UGT1A1 GO:0042493| response to drug UGT1A1;TYMS 36521:[DB06817 DB09027] DB06817|Raltegravir pol;UGT1A1 DB09027|Ledipasvir ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug UGT1A1;ABCG2;ABCB1 36522:[DB06817 DB02187] DB06817|Raltegravir pol;UGT1A1 DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0008210| estrogen metabolic process UGT1A1;HSD17B1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36523:[DB06817 DB01207] DB06817|Raltegravir pol;UGT1A1 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0007584| response to nutrient UGT1A1;TBXA2R GO:0045471| response to ethanol TBXA2R;UGT1A1 GO:0042493| response to drug TBXA2R;UGT1A1 GO:0032496| response to lipopolysaccharide TBXA2R;UGT1A1 36524:[DB06817 DB00043] DB06817|Raltegravir pol;UGT1A1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways 36525:[DB06817 DB01194] DB06817|Raltegravir pol;UGT1A1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0010033| response to organic substance UGT1A1;CA2 GO:0045471| response to ethanol CA3;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36526:[DB06817 DB09343] DB06817|Raltegravir pol;UGT1A1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0008152| metabolic process TYMP;UGT1A1 36527:[DB06817 DB00240] DB06817|Raltegravir pol;UGT1A1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36528:[DB06817 DB00954] DB06817|Raltegravir pol;UGT1A1 DB00954|Dirithromycin CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36529:[DB06817 DB06600] DB06817|Raltegravir pol;UGT1A1 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 36530:[DB06817 DB08910] DB06817|Raltegravir pol;UGT1A1 DB08910|Pomalidomide CRBN;TNF;PTGS2;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0010033| response to organic substance TNF;UGT1A1;PTGS2;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1;TNF GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;CYP1A2 36531:[DB06817 DB06176] DB06817|Raltegravir pol;UGT1A1 DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes common pathways GO:0010033| response to organic substance HDAC6;CYP1A1;UGT1A1 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP3A5;CYP1A1;CYP2C19;UGT1A1 GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP1A1;CYP2C19;UGT1A1 GO:0042493| response to drug ABCB1;HDAC4;HDAC2;ABCC1;UGT1A1;HDAC1;CYP1A1 GO:0032496| response to lipopolysaccharide UGT1A1;HDAC2;HDAC1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP1A1;CYP3A4 36532:[DB06817 DB00846] DB06817|Raltegravir pol;UGT1A1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 36533:[DB06817 DB01125] DB06817|Raltegravir pol;UGT1A1 DB01125|Anisindione GGCX common genes common pathways 36534:[DB06817 DB00748] DB06817|Raltegravir pol;UGT1A1 DB00748|Carbinoxamine HRH1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0042493| response to drug CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2E1;UGT1A1;CYP2C19;CYP2C8 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C19;CYP2C8;CYP2E1 36535:[DB06817 DB01606] DB06817|Raltegravir pol;UGT1A1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways 36536:[DB06817 DB00360] DB06817|Raltegravir pol;UGT1A1 DB00360|Sapropterin PAH;NOS3;TH;TPH1;PTGS2 common genes common pathways GO:0032496| response to lipopolysaccharide TH;PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;TH;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;TH GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0008152| metabolic process UGT1A1;PAH GO:0045471| response to ethanol TH;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound TH;PTGS2;UGT1A1 36537:[DB06817 DB00481] DB06817|Raltegravir pol;UGT1A1 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes UGT1A1 common pathways GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0042493| response to drug UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion TFF1;UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0017144| drug metabolic process CYP2B6;CYP3A4;CYP2C8;AOX1;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR2;ESR1;UGT1A1 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2C8;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0051552| flavone metabolic process UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 36538:[DB06817 DB01009] DB06817|Raltegravir pol;UGT1A1 DB01009|Ketoprofen PTGS1;PTGS2;CXCR1;CYP2C9;CYP2C8;UGT1A1;ALB;ABCC4;SLCO1A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes UGT1A1 common pathways GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0001889| liver development UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0014070| response to organic cyclic compound ABCC4;PTGS2;UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0042493| response to drug ABCC4;UGT1A1;PTGS2 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C9 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2C9 GO:0031100| organ regeneration UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance ABCC4;PTGS2;UGT1A1 36539:[DB06817 DB01536] DB06817|Raltegravir pol;UGT1A1 DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;AKR1C3;CYP3A4 GO:0008210| estrogen metabolic process HSD17B1;UGT1A1 GO:0007584| response to nutrient UGT1A1;AKR1C3 GO:0008152| metabolic process HSD3B1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36540:[DB06817 DB12095] DB06817|Raltegravir pol;UGT1A1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;TPH2 36541:[DB06817 DB12498] DB06817|Raltegravir pol;UGT1A1 DB12498|Mogamulizumab CXCR4 common genes common pathways 36542:[DB06817 DB11967] DB06817|Raltegravir pol;UGT1A1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes UGT1A1 common pathways GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0001889| liver development UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2C19;UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus IL6;UGT1A1;TNF GO:0042167| heme catabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0006953| acute-phase response UGT1A1;IL6 GO:0008210| estrogen metabolic process UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide IL1B;CYP1A2;UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;TNF GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP2C19;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 36543:[DB06817 DB00629] DB06817|Raltegravir pol;UGT1A1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 36544:[DB06817 DB01632] DB06817|Raltegravir pol;UGT1A1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0008152| metabolic process UCKL1;UGT1A1 36545:[DB06817 DB00562] DB06817|Raltegravir pol;UGT1A1 DB00562|Benzthiazide SLC12A3;CA1;CA2;CA4;CA9;CA12 common genes common pathways GO:0042493| response to drug UGT1A1;CA9 GO:0010033| response to organic substance CA2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 36546:[DB06817 DB05812] DB06817|Raltegravir pol;UGT1A1 DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0006953| acute-phase response UGT1A1;ORM1 GO:0042493| response to drug ABCC1;UGT1A1;CYP1A2 GO:0007586| digestion UGT1A1;SULT2A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0008202| steroid metabolic process CYP17A1;UGT1A1;CYP2C8;CYP2C19;CYP1A2;CYP2C9;CYP2D6;CYP3A4;SULT2A1 36547:[DB06817 DB00054] DB06817|Raltegravir pol;UGT1A1 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways 36548:[DB06817 DB01277] DB06817|Raltegravir pol;UGT1A1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0031100| organ regeneration IGF2R;UGT1A1 GO:0001889| liver development IGF2R;UGT1A1 36549:[DB06817 DB00461] DB06817|Raltegravir pol;UGT1A1 DB00461|Nabumetone PTGS2;PTGS1;MPO;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide MPO;UGT1A1;PTGS2;CYP1A2 GO:0042493| response to drug UGT1A1;PTGS2;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1;PTGS2 36550:[DB06817 DB02746] DB06817|Raltegravir pol;UGT1A1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0042594| response to starvation UGT1A1;PPARG GO:0042493| response to drug PPARG;UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;ESR2;UGT1A1 GO:0031100| organ regeneration UGT1A1;PPARG GO:0010033| response to organic substance PPARG;PPARD;UGT1A1 36551:[DB06817 DB02558] DB06817|Raltegravir pol;UGT1A1 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways 36552:[DB06817 DB14060] DB06817|Raltegravir pol;UGT1A1 DB14060|NS-398 PTGS2 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 36553:[DB06817 DB00005] DB06817|Raltegravir pol;UGT1A1 DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0007584| response to nutrient UGT1A1;LTA GO:0010033| response to organic substance UGT1A1;TNF GO:0032496| response to lipopolysaccharide TNFRSF1B;LTA;UGT1A1 GO:0042493| response to drug LTA;UGT1A1 36554:[DB06817 DB01180] DB06817|Raltegravir pol;UGT1A1 DB01180|Rescinnamine ACE common genes common pathways 36555:[DB06817 DB00310] DB06817|Raltegravir pol;UGT1A1 DB00310|Chlorthalidone SLC12A1 common genes common pathways 36556:[DB06817 DB00216] DB06817|Raltegravir pol;UGT1A1 DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP3A4 GO:0045471| response to ethanol HTR1B;UGT1A1 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2A6;CYP2D6;CYP2C9 GO:0017144| drug metabolic process CYP2C9;CYP2D6;CYP2A6;CYP3A4;UGT1A1;CYP2C19 GO:0042493| response to drug UGT1A1;HTR2B;ABCB1;HTR1B 36557:[DB06817 DB12537] DB06817|Raltegravir pol;UGT1A1 DB12537|Benzodiazepine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36558:[DB06817 DB12589] DB06817|Raltegravir pol;UGT1A1 DB12589|Dacetuzumab CD40 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;CD40 36559:[DB06817 DB04886] DB06817|Raltegravir pol;UGT1A1 DB04886|Calanolide A CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36560:[DB06817 DB07615] DB06817|Raltegravir pol;UGT1A1 DB07615|Tranilast HPGDS;CYP3A4;CYP2C9 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36561:[DB06817 DB05075] DB06817|Raltegravir pol;UGT1A1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways 36562:[DB06817 DB05095] DB06817|Raltegravir pol;UGT1A1 DB05095|Cimicoxib PTGS2;PTGS2 common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 36563:[DB06817 DB00067] DB06817|Raltegravir pol;UGT1A1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0010033| response to organic substance AVPR1A;UGT1A1 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0042493| response to drug UGT1A1;ABCC2 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0032870| cellular response to hormone stimulus AVPR1B;UGT1A1;AVPR1A;ABCC2;AVPR2 36564:[DB06817 DB02902] DB06817|Raltegravir pol;UGT1A1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways GO:0008202| steroid metabolic process SULT1E1;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;SULT1E1 36565:[DB06817 DB00789] DB06817|Raltegravir pol;UGT1A1 DB00789|Gadopentetic acid PGD common genes common pathways 36566:[DB06817 DB04599] DB06817|Raltegravir pol;UGT1A1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1 GO:0042493| response to drug UGT1A1;DRD2;HTR2A 36567:[DB06817 DB01667] DB06817|Raltegravir pol;UGT1A1 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2;PNP GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 36568:[DB06817 DB00935] DB06817|Raltegravir pol;UGT1A1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug UGT1A1;ADRA1A 36569:[DB06817 DB01341] DB06817|Raltegravir pol;UGT1A1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways 36570:[DB06817 DB00763] DB06817|Raltegravir pol;UGT1A1 DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;CYP2C19;UGT1A1;CYP2E1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;CYP2E1;UGT1A1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1;CYP2C19;CYP1A2;CYP2C9;CYP2B6;CYP2D6;CYP3A4;CYP2A6 GO:0017144| drug metabolic process CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP2A6;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 36571:[DB06817 DB08868] DB06817|Raltegravir pol;UGT1A1 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0008152| metabolic process SPHK1;UGT1A1 GO:0042493| response to drug UGT1A1;HDAC1;CYP2E1 GO:0032496| response to lipopolysaccharide UGT1A1;HDAC1 GO:0008202| steroid metabolic process CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP4F2;CYP4F12 36572:[DB06817 DB09274] DB06817|Raltegravir pol;UGT1A1 DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2A6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2A6;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36573:[DB06817 DB11919] DB06817|Raltegravir pol;UGT1A1 DB11919|6-O-benzylguanine CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36574:[DB06817 DB08907] DB06817|Raltegravir pol;UGT1A1 DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008152| metabolic process UGT1A1;UGT2B4;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A9;UGT2B4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP3A4 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:1904224| UGT1A9;UGT1A1 GO:0042493| response to drug ABCC2;ABCB1;UGT1A1 GO:0006953| acute-phase response ORM1;UGT1A1 36575:[DB06817 DB12248] DB06817|Raltegravir pol;UGT1A1 DB12248|Tulobuterol ADRB2 common genes common pathways 36576:[DB06817 DB11575] DB06817|Raltegravir pol;UGT1A1 DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36577:[DB06817 DB08881] DB06817|Raltegravir pol;UGT1A1 DB08881|Vemurafenib BRAF;CYP1A2;CYP2D6;CYP3A4;CYP2C9;CYP2C8;CYP2B6;ALB;ORM1;ABCC1;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug ABCC1;UGT1A1;ABCG2;CYP1A2 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;CYP2D6;CYP2C9;CYP2B6;CYP3A4;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP2D6;CYP1A2;CYP3A4;UGT1A1;CYP2C8 GO:0010033| response to organic substance CYP1A2;UGT1A1 36578:[DB06817 DB11327] DB06817|Raltegravir pol;UGT1A1 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;NOS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 36579:[DB06817 DB14542] DB06817|Raltegravir pol;UGT1A1 DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;ANXA1 GO:0032870| cellular response to hormone stimulus UGT1A1;CYP11B2;CYP11B1 GO:0051384| response to glucocorticoid stimulus UGT1A1;HSD11B2;ANXA1 GO:0008152| metabolic process UGT1A1;HSD3B1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1;HSD11B2 GO:0008202| steroid metabolic process CYP3A4;UGT1A1;CYP2C8;CYP11B2;CYP3A5;CYP3A7;CYP11B1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1;ANXA1 GO:0042493| response to drug ABCB1;HSD11B2;ANXA1;ABCG2;UGT1A1 36580:[DB06817 DB00626] DB06817|Raltegravir pol;UGT1A1 DB00626|Bacitracin IDE;A2M common genes common pathways GO:0008152| metabolic process IDE;UGT1A1 36581:[DB06817 DB11574] DB06817|Raltegravir pol;UGT1A1 DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36582:[DB06817 DB00583] DB06817|Raltegravir pol;UGT1A1 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0008152| metabolic process CES1;UGT1A1 GO:0014070| response to organic cyclic compound CPT1A;UGT1A1 GO:0042493| response to drug UGT1A1;CPT1A GO:0032496| response to lipopolysaccharide MPO;UGT1A1 36583:[DB06817 DB05212] DB06817|Raltegravir pol;UGT1A1 DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;NFKB2 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36584:[DB06817 DB11828] DB06817|Raltegravir pol;UGT1A1 DB11828|Neratinib EGFR;CYP3A4;FMO3;ALB;ORM1;ORM2;ABCB1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1 GO:0006953| acute-phase response ORM2;UGT1A1;ORM1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0014070| response to organic cyclic compound EGFR;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0001889| liver development EGFR;UGT1A1 36585:[DB06817 DB05281] DB06817|Raltegravir pol;UGT1A1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0051384| response to glucocorticoid stimulus BCL2;UGT1A1 GO:0048545| response to steroid hormone stimulus BCL2;UGT1A1 GO:0042493| response to drug BCL2;UGT1A1 36586:[DB06817 DB06439] DB06817|Raltegravir pol;UGT1A1 DB06439|Tyloxapol LPL common genes common pathways GO:0042493| response to drug LPL;UGT1A1 36587:[DB06817 DB12702] DB06817|Raltegravir pol;UGT1A1 DB12702|Velusetrag HTR4 common genes common pathways 36588:[DB06817 DB03554] DB06817|Raltegravir pol;UGT1A1 DB03554|5-Iodouracil DPYD common genes common pathways 36589:[DB06817 DB04356] DB06817|Raltegravir pol;UGT1A1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 36590:[DB06817 DB00901] DB06817|Raltegravir pol;UGT1A1 DB00901|Bitolterol ADRB2 common genes common pathways 36591:[DB06817 DB00692] DB06817|Raltegravir pol;UGT1A1 DB00692|Phentolamine ADRA2A;ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0042493| response to drug ADRA1A;UGT1A1 36592:[DB06817 DB01303] DB06817|Raltegravir pol;UGT1A1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;HDAC2;UGT1A1 GO:0042493| response to drug ADORA2A;UGT1A1;HDAC2;PDE3A;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 36593:[DB06817 DB08341] DB06817|Raltegravir pol;UGT1A1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0045471| response to ethanol PTK2B;UGT1A1 GO:0042493| response to drug PTK2B;UGT1A1 36594:[DB06817 DB13627] DB06817|Raltegravir pol;UGT1A1 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 36595:[DB06817 DB00535] DB06817|Raltegravir pol;UGT1A1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0032496| response to lipopolysaccharide MPO;UGT1A1 GO:0007586| digestion SLC15A1;UGT1A1 36596:[DB06817 DB05481] DB06817|Raltegravir pol;UGT1A1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways GO:0006953| acute-phase response UGT1A1;SERPINA1 36597:[DB06817 DB13456] DB06817|Raltegravir pol;UGT1A1 DB13456|Midecamycin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36598:[DB06817 DB14520] DB06817|Raltegravir pol;UGT1A1 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:0010033| response to organic substance UGT1A1;CALR GO:0042493| response to drug CALR;UGT1A1 36599:[DB06817 DB11799] DB06817|Raltegravir pol;UGT1A1 DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes pol;UGT1A1 common pathways GO:0042594| response to starvation UGT1A1 GO:0007586| digestion UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:1904224| UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0042493| response to drug UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 36600:[DB06817 DB00025] DB06817|Raltegravir pol;UGT1A1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0010033| response to organic substance UGT1A1;CALR GO:0042493| response to drug CALR;UGT1A1 GO:0006953| acute-phase response F2;UGT1A1 GO:0001889| liver development UGT1A1;PROC 36601:[DB06817 DB12329] DB06817|Raltegravir pol;UGT1A1 DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36602:[DB06817 DB01365] DB06817|Raltegravir pol;UGT1A1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug ADRA1A;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 36603:[DB06817 DB09211] DB06817|Raltegravir pol;UGT1A1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;PTGER1;PTGER4;PTGER2 36604:[DB06817 DB01011] DB06817|Raltegravir pol;UGT1A1 DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2E1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0032870| cellular response to hormone stimulus UGT1A1;CYP11B2;CYP11B1 GO:0042493| response to drug UGT1A1;CYP2E1 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4;CYP2A6 GO:0008202| steroid metabolic process CYP11B1;CYP2E1;UGT1A1;CYP11B2;CYP3A4;CYP2A6 36605:[DB06817 DB00219] DB06817|Raltegravir pol;UGT1A1 DB00219|Oxyphenonium CHRM1 common genes common pathways 36606:[DB06817 DB13928] DB06817|Raltegravir pol;UGT1A1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug UGT1A1;LPL GO:0007586| digestion UGT1A1;AMY1A GO:0008152| metabolic process AMY1A;UGT1A1 36607:[DB06817 DB06771] DB06817|Raltegravir pol;UGT1A1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 36608:[DB06817 DB06800] DB06817|Raltegravir pol;UGT1A1 DB06800|Methylnaltrexone OPRM1;OPRK1 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRM1;OPRK1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 36609:[DB06817 DB13139] DB06817|Raltegravir pol;UGT1A1 DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 36610:[DB06817 DB01152] DB06817|Raltegravir pol;UGT1A1 DB01152|Candicidin CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36611:[DB06817 DB00354] DB06817|Raltegravir pol;UGT1A1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways 36612:[DB06817 DB14512] DB06817|Raltegravir pol;UGT1A1 DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36613:[DB06817 DB00185] DB06817|Raltegravir pol;UGT1A1 DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4;FMO1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0007586| digestion CHRM3;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;FMO1 36614:[DB06817 DB01419] DB06817|Raltegravir pol;UGT1A1 DB01419|Antrafenine PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36615:[DB06817 DB09123] DB06817|Raltegravir pol;UGT1A1 DB09123|Dienogest PGR;AR;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36616:[DB06817 DB09325] DB06817|Raltegravir pol;UGT1A1 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 36617:[DB06817 DB06626] DB06817|Raltegravir pol;UGT1A1 DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes UGT1A1 common pathways GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0008152| metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4;CYP1A2 GO:0001889| liver development UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP3A4;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C19;CYP3A5 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:1904224| UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2;ABCB1 36618:[DB06817 DB07991] DB06817|Raltegravir pol;UGT1A1 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 36619:[DB06817 DB05562] DB06817|Raltegravir pol;UGT1A1 DB05562|Naluzotan HTR1A common genes common pathways 36620:[DB06817 DB06454] DB06817|Raltegravir pol;UGT1A1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD2;UGT1A1;DRD3 GO:0045471| response to ethanol DRD3;UGT1A1;DRD2 36621:[DB06817 DB14126] DB06817|Raltegravir pol;UGT1A1 DB14126|Tenofovir ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 36622:[DB06817 DB00677] DB06817|Raltegravir pol;UGT1A1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0042493| response to drug UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 36623:[DB06817 DB00136] DB06817|Raltegravir pol;UGT1A1 DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36624:[DB06817 DB11323] DB06817|Raltegravir pol;UGT1A1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 36625:[DB06817 DB14544] DB06817|Raltegravir pol;UGT1A1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0008152| metabolic process UGT1A1;HSD3B1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;ANXA1 GO:0032870| cellular response to hormone stimulus CYP11B2;UGT1A1;CYP11B1 GO:0051384| response to glucocorticoid stimulus ANXA1;HSD11B2;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;NR3C1;UGT1A1 GO:0042493| response to drug ANXA1;HSD11B2;ABCB1;ABCG2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;HSD11B2 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP11B2;CYP3A5;CYP11B1;CYP3A7;CYP3A4 36626:[DB06817 DB14481] DB06817|Raltegravir pol;UGT1A1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0010033| response to organic substance CASQ1;CALR;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;SPARC GO:0042493| response to drug SLC8A1;SLC34A1;CALR;UGT1A1 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0051384| response to glucocorticoid stimulus S100B;SPARC;UGT1A1 GO:0007584| response to nutrient UGT1A1;SLC34A1;SLC8A1 GO:0014070| response to organic cyclic compound CASR;UGT1A1 GO:0045471| response to ethanol UGT1A1;SPARC GO:0001889| liver development UGT1A1;RGN 36627:[DB06817 DB09308] DB06817|Raltegravir pol;UGT1A1 DB09308|Solithromycin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36628:[DB06817 DB08927] DB06817|Raltegravir pol;UGT1A1 DB08927|Amperozide HTR2A common genes common pathways GO:0042493| response to drug HTR2A;UGT1A1 36629:[DB06817 DB00017] DB06817|Raltegravir pol;UGT1A1 DB00017|Salmon Calcitonin CALCR common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;CALCR 36630:[DB06817 DB05266] DB06817|Raltegravir pol;UGT1A1 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0042493| response to drug UGT1A1;PDE3A 36631:[DB06817 DB13757] DB06817|Raltegravir pol;UGT1A1 DB13757|Epanolol CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 36632:[DB06817 DB01071] DB06817|Raltegravir pol;UGT1A1 DB01071|Mequitazine HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 36633:[DB06817 DB01427] DB06817|Raltegravir pol;UGT1A1 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 GO:0010033| response to organic substance TNF;UGT1A1 GO:0042493| response to drug UGT1A1;PDE3A 36634:[DB06817 DB00349] DB06817|Raltegravir pol;UGT1A1 DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways GO:0042493| response to drug SLC6A11;UGT1A1;GABRG3;ABCB1 GO:0010033| response to organic substance UGT1A1;SLC6A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2B6;CYP2D6;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2B6;CYP2D6 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A1 36635:[DB06817 DB05229] DB06817|Raltegravir pol;UGT1A1 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;PTGIR GO:0008202| steroid metabolic process CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP2C8;UGT1A1 36636:[DB06817 DB05488] DB06817|Raltegravir pol;UGT1A1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 36637:[DB06817 DB14541] DB06817|Raltegravir pol;UGT1A1 DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0048545| response to steroid hormone stimulus UGT1A1;HSD11B2 GO:0008202| steroid metabolic process CYP3A4;CYP11B2;UGT1A1;CYP2C8;CYP3A7;CYP11B1;CYP3A5 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;NR3C1;UGT1A1 GO:0042493| response to drug ANXA1;HSD11B2;ABCB1;ABCG2;UGT1A1 GO:0032870| cellular response to hormone stimulus CYP11B2;UGT1A1;CYP11B1 GO:0051384| response to glucocorticoid stimulus HSD11B2;ANXA1;UGT1A1 GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0008152| metabolic process UGT1A1;HSD3B1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36638:[DB06817 DB01037] DB06817|Raltegravir pol;UGT1A1 DB01037|Selegiline MAOB;MAOA;CYP2B6;CYP3A4;CYP2A6;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0045471| response to ethanol UGT1A1;MAOB;CYP2E1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;UGT1A1;CYP2C19;CYP2E1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0017144| drug metabolic process CYP2B6;CYP2C9;CYP2D6;CYP1A2;CYP2A6;CYP3A4;CYP2E1;UGT1A1;CYP2C8;CYP2C19 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C9;CYP2B6;CYP2C19;CYP2C8;UGT1A1;CYP2E1 GO:0042493| response to drug ABCB1;CYP1A2;UGT1A1;MAOB;CYP2E1 GO:0032496| response to lipopolysaccharide UGT1A1;MAOB;CYP1A2 36639:[DB06817 DB09006] DB06817|Raltegravir pol;UGT1A1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0042493| response to drug PPARG;UGT1A1 GO:0042594| response to starvation PPARG;UGT1A1 GO:0010033| response to organic substance UGT1A1;PPARG;PPARD GO:0031100| organ regeneration UGT1A1;PPARG GO:0014070| response to organic cyclic compound PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG 36640:[DB06817 DB00979] DB06817|Raltegravir pol;UGT1A1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0042493| response to drug BCHE;UGT1A1 GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0007584| response to nutrient BCHE;UGT1A1 36641:[DB06817 DB07577] DB06817|Raltegravir pol;UGT1A1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug UGT1A1;TYMS GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0045471| response to ethanol UGT1A1;TYMS 36642:[DB06817 DB09318] DB06817|Raltegravir pol;UGT1A1 DB09318|Synthetic Conjugated Estrogens, B ESR1;CYP3A4 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36643:[DB06817 DB00928] DB06817|Raltegravir pol;UGT1A1 DB00928|Azacitidine DNMT1;CDA common genes common pathways 36644:[DB06817 DB09369] DB06817|Raltegravir pol;UGT1A1 DB09369|Polyestradiol phosphate ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 36645:[DB06817 DB08734] DB06817|Raltegravir pol;UGT1A1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0042493| response to drug TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus TYMS;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0045471| response to ethanol UGT1A1;TYMS 36646:[DB06817 DB09116] DB06817|Raltegravir pol;UGT1A1 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0042493| response to drug CAT;UGT1A1 GO:0008152| metabolic process UGT1A1;ALDH3B2 GO:0045471| response to ethanol CAT;UGT1A1 36647:[DB06817 DB09347] DB06817|Raltegravir pol;UGT1A1 DB09347|Acetrizoic acid ALB common genes common pathways 36648:[DB06817 DB05029] DB06817|Raltegravir pol;UGT1A1 DB05029|Lancovutide PLA2G4A common genes common pathways GO:0008152| metabolic process PLA2G4A;UGT1A1 36649:[DB06817 DB00262] DB06817|Raltegravir pol;UGT1A1 DB00262|Carmustine GSR;CYP1A2 common genes common pathways GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 36650:[DB06817 DB13520] DB06817|Raltegravir pol;UGT1A1 DB13520|Metergoline SCN2A common genes common pathways 36651:[DB06817 DB14019] DB06817|Raltegravir pol;UGT1A1 DB14019|Fosnetupitant CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36652:[DB06817 DB09059] DB06817|Raltegravir pol;UGT1A1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0042493| response to drug UGT1A1;OXTR GO:0048545| response to steroid hormone stimulus OXTR;UGT1A1 GO:0010033| response to organic substance UGT1A1;AVPR1A GO:0032870| cellular response to hormone stimulus AVPR1B;UGT1A1;AVPR2;AVPR1A;OXTR GO:0014070| response to organic cyclic compound OXTR;UGT1A1 36653:[DB06817 DB01454] DB06817|Raltegravir pol;UGT1A1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0042493| response to drug SLC6A4;HTR2C;HTR2B;UGT1A1;SLC6A2;SLC6A3;HTR2A GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0045471| response to ethanol SLC6A3;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0007584| response to nutrient UGT1A1;SLC6A4 36654:[DB06817 DB00204] DB06817|Raltegravir pol;UGT1A1 DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36655:[DB06817 DB05459] DB06817|Raltegravir pol;UGT1A1 DB05459|Briakinumab IL12B;IL23A common genes common pathways GO:0010033| response to organic substance UGT1A1;IL12B 36656:[DB06817 DB13003] DB06817|Raltegravir pol;UGT1A1 DB13003|Cortivazol NR3C1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 36657:[DB06817 DB00914] DB06817|Raltegravir pol;UGT1A1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;KCNJ8 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;PRKAA1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0071361| cellular response to ethanol UGT1A1;PRKAA1 36658:[DB06817 DB01956] DB06817|Raltegravir pol;UGT1A1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0001889| liver development BAAT;UGT1A1 GO:0045471| response to ethanol UGT1A1;GRIN2B GO:0071361| cellular response to ethanol GLRA1;GLRA2;UGT1A1 GO:0031100| organ regeneration UGT1A1;BAAT GO:0042493| response to drug UGT1A1;GABRG3 GO:0007586| digestion SLC15A1;UGT1A1 36659:[DB06817 DB00469] DB06817|Raltegravir pol;UGT1A1 DB00469|Tenoxicam PTGS2;PTGS1;CYP2C9;SLC22A8 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C9 GO:0017144| drug metabolic process UGT1A1;CYP2C9 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 36660:[DB06817 DB00489] DB06817|Raltegravir pol;UGT1A1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 36661:[DB06817 DB02261] DB06817|Raltegravir pol;UGT1A1 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0032496| response to lipopolysaccharide PTAFR;UGT1A1 36662:[DB06817 DB00248] DB06817|Raltegravir pol;UGT1A1 DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol UGT1A1;DRD2;HTR1B;DRD3 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug HTR2C;DRD3;HTR1B;ABCB1;ADRA1A;DRD2;HTR2A;DRD1;UGT1A1;HTR2B 36663:[DB06817 DB00730] DB06817|Raltegravir pol;UGT1A1 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A1;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;CYP1A2 GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP1A2;CYP1A1;UGT1A1 36664:[DB06817 DB04978] DB06817|Raltegravir pol;UGT1A1 DB04978|SP1049C TOP2A common genes common pathways 36665:[DB06817 DB05205] DB06817|Raltegravir pol;UGT1A1 DB05205|CX157 MAOA common genes common pathways 36666:[DB06817 DB00761] DB06817|Raltegravir pol;UGT1A1 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0042493| response to drug UGT1A1;SLC12A5 36667:[DB06817 DB01028] DB06817|Raltegravir pol;UGT1A1 DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;CYP3A4;CYP2E1;UGT1A1 GO:0071361| cellular response to ethanol GLRA1;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;MT-ND1;CYP1A2 GO:0042493| response to drug CYP2E1;UGT1A1;CYP1A2;MT-ND1;GABRG3 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2E1;CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C9;CYP2B6 GO:0017144| drug metabolic process CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C9;CYP2B6;UGT1A1;CYP2E1 36668:[DB06817 DB11714] DB06817|Raltegravir pol;UGT1A1 DB11714|Durvalumab CD274;CD80 common genes common pathways 36669:[DB06817 DB14025] DB06817|Raltegravir pol;UGT1A1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP1A2;CYP2C9;CYP2D6 GO:0017144| drug metabolic process CYP2D6;CYP2C9;CYP1A2;CYP2C19;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 36670:[DB06817 DB14634] DB06817|Raltegravir pol;UGT1A1 DB14634|Fluprednidene acetate CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36671:[DB06817 DB04690] DB06817|Raltegravir pol;UGT1A1 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug UGT1A1;ABCG2;TOP1;ABCB1 36672:[DB06817 DB02486] DB06817|Raltegravir pol;UGT1A1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways GO:0008152| metabolic process GSTA1;UGT1A1 36673:[DB06817 DB06543] DB06817|Raltegravir pol;UGT1A1 DB06543|Astaxanthin NFKBIA common genes common pathways GO:0032496| response to lipopolysaccharide NFKBIA;UGT1A1 36674:[DB06817 DB00154] DB06817|Raltegravir pol;UGT1A1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 36675:[DB06817 DB12278] DB06817|Raltegravir pol;UGT1A1 DB12278|Propiverine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CACNA1C;ADRA1A;CYP3A4;FMO1;FMO3;CYP2B common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;FMO1;CYP3A4 GO:0042493| response to drug ADRA1A;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;FMO1 GO:0007586| digestion UGT1A1;CHRM3 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36676:[DB06817 DB00221] DB06817|Raltegravir pol;UGT1A1 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways 36677:[DB06817 DB05227] DB06817|Raltegravir pol;UGT1A1 DB05227|APD791 HTR2A common genes common pathways GO:0042493| response to drug UGT1A1;HTR2A 36678:[DB06817 DB08908] DB06817|Raltegravir pol;UGT1A1 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0032496| response to lipopolysaccharide RELA;UGT1A1 GO:0042493| response to drug RELA;UGT1A1 GO:0010033| response to organic substance UGT1A1;RELA GO:0001889| liver development RELA;UGT1A1 GO:0014070| response to organic cyclic compound RELA;UGT1A1 36679:[DB06817 DB05104] DB06817|Raltegravir pol;UGT1A1 DB05104|Asimadoline OPRK1 common genes common pathways GO:0045471| response to ethanol OPRK1;UGT1A1 36680:[DB06817 DB09071] DB06817|Raltegravir pol;UGT1A1 DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 36681:[DB06817 DB05706] DB06817|Raltegravir pol;UGT1A1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways 36682:[DB06817 DB04487] DB06817|Raltegravir pol;UGT1A1 DB04487|N-Methylleucine CXCL10 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;CXCL10 36683:[DB06817 DB02123] DB06817|Raltegravir pol;UGT1A1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways 36684:[DB06817 DB00817] DB06817|Raltegravir pol;UGT1A1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 36685:[DB06817 DB09076] DB06817|Raltegravir pol;UGT1A1 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0007586| digestion UGT1A1;CHRM3 GO:0042493| response to drug UGT1A1;ABCB1 36686:[DB06817 DB00665] DB06817|Raltegravir pol;UGT1A1 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2C19 GO:0042493| response to drug UGT1A1;POR GO:0007584| response to nutrient POR;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19 36687:[DB06817 DB00605] DB06817|Raltegravir pol;UGT1A1 DB00605|Sulindac PTGS2;PTGS1;AKR1B1;MAPK3;PPARD;PTGDR2;AKR1B10;CYP1A1;ALB;SLC22A6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP1A1 GO:0008202| steroid metabolic process AKR1B10;UGT1A1;CYP1A1 GO:0010033| response to organic substance UGT1A1;AKR1B1;PTGS2;CYP1A1;PPARD GO:0007586| digestion AKR1B10;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2;UGT1A1;MAPK3 GO:0042493| response to drug CYP1A1;PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1 36688:[DB06817 DB05187] DB06817|Raltegravir pol;UGT1A1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0042493| response to drug PPARG;UGT1A1 GO:0042594| response to starvation UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG;PPARD GO:0031100| organ regeneration PPARG;UGT1A1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound UGT1A1;PPARG 36689:[DB06817 DB05838] DB06817|Raltegravir pol;UGT1A1 DB05838|OPC-51803 AVPR2 common genes common pathways GO:0032870| cellular response to hormone stimulus AVPR2;UGT1A1 36690:[DB06817 DB01355] DB06817|Raltegravir pol;UGT1A1 DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;CYP2C19;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1 36691:[DB06817 DB06080] DB06817|Raltegravir pol;UGT1A1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0031100| organ regeneration UGT1A1;FLT3 36692:[DB06817 DB00651] DB06817|Raltegravir pol;UGT1A1 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0042493| response to drug ADORA2A;UGT1A1 36693:[DB06817 DB06230] DB06817|Raltegravir pol;UGT1A1 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0051552| flavone metabolic process UGT1A8;UGT1A1 GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 GO:0008152| metabolic process UGT1A3;UGT1A8;UGT1A1;UGT2B7 GO:0043086| negative regulation of catalytic activity UGT1A8;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A8;UGT1A3;UGT1A1 GO:0052695| cellular glucuronidation UGT2B7;UGT1A1;UGT1A8;UGT1A3 GO:0045939| negative regulation of steroid metabolic process UGT1A8;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A8;UGT1A3 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 GO:1904224| UGT1A1;UGT1A8;UGT1A3 GO:0008202| steroid metabolic process UGT2B7;UGT1A1;UGT1A8 GO:0017144| drug metabolic process UGT1A1;UGT1A8;UGT1A3 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3;UGT1A8 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A8;UGT1A3 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A8;UGT1A3 36694:[DB06817 DB11182] DB06817|Raltegravir pol;UGT1A1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways GO:0008152| metabolic process UGT1A1;LYZ 36695:[DB06817 DB09048] DB06817|Raltegravir pol;UGT1A1 DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C9;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP3A4;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;TACR1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0045471| response to ethanol UGT1A1;TACR1 36696:[DB06817 DB14007] DB06817|Raltegravir pol;UGT1A1 DB14007|Pentetic acid SERPINA1 common genes common pathways GO:0006953| acute-phase response SERPINA1;UGT1A1 36697:[DB06817 DB02527] DB06817|Raltegravir pol;UGT1A1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0010033| response to organic substance ABCC4;UGT1A1 GO:0042493| response to drug UGT1A1;ABCC4 GO:0014070| response to organic cyclic compound ABCC4;UGT1A1 36698:[DB06817 DB09216] DB06817|Raltegravir pol;UGT1A1 DB09216|Tolfenamic Acid PTGS1;PTGS2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36699:[DB06817 DB07954] DB06817|Raltegravir pol;UGT1A1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0043086| negative regulation of catalytic activity PDE6G;UGT1A1 GO:0008152| metabolic process PDE2A;PDE5A;UGT1A1 36700:[DB06817 DB11363] DB06817|Raltegravir pol;UGT1A1 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug UGT1A1;ABCG2;ABCB1 36701:[DB06817 DB08889] DB06817|Raltegravir pol;UGT1A1 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0014070| response to organic cyclic compound UGT1A1;PSMB2 36702:[DB06817 DB11605] DB06817|Raltegravir pol;UGT1A1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A7;CYP3A5;CYP3A4;NR1I2 36703:[DB06817 DB08602] DB06817|Raltegravir pol;UGT1A1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways 36704:[DB06817 DB09301] DB06817|Raltegravir pol;UGT1A1 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways GO:0007584| response to nutrient UGT1A1;ARSB GO:0008152| metabolic process IDUA;UGT1A1;ARSB;GUSB;HEXB;GALNS;IDS 36705:[DB06817 DB05316] DB06817|Raltegravir pol;UGT1A1 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1 GO:0042493| response to drug HTR2A;DRD2;UGT1A1 36706:[DB06817 DB01414] DB06817|Raltegravir pol;UGT1A1 DB01414|Cefacetrile mrcA;SLC22A6;SLC22A8 common genes common pathways 36707:[DB06817 DB01192] DB06817|Raltegravir pol;UGT1A1 DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0045471| response to ethanol UGT1A1;OPRM1 36708:[DB06817 DB04714] DB06817|Raltegravir pol;UGT1A1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0008202| steroid metabolic process FDPS;UGT1A1 36709:[DB06817 DB09477] DB06817|Raltegravir pol;UGT1A1 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways GO:0032496| response to lipopolysaccharide BDKRB1;UGT1A1 36710:[DB06817 DB08795] DB06817|Raltegravir pol;UGT1A1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 36711:[DB06817 DB09240] DB06817|Raltegravir pol;UGT1A1 DB09240|Niludipine CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36712:[DB06817 DB13421] DB06817|Raltegravir pol;UGT1A1 DB13421|Edoxudine ALB common genes common pathways 36713:[DB06817 DB12023] DB06817|Raltegravir pol;UGT1A1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways 36714:[DB06817 DB05423] DB06817|Raltegravir pol;UGT1A1 DB05423|ORG-34517 NR3C1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 36715:[DB06817 DB05415] DB06817|Raltegravir pol;UGT1A1 DB05415|OSI-461 PDE5A common genes common pathways GO:0008152| metabolic process UGT1A1;PDE5A 36716:[DB06817 DB04076] DB06817|Raltegravir pol;UGT1A1 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;PNP;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;UGT1A1 36717:[DB06817 DB05971] DB06817|Raltegravir pol;UGT1A1 DB05971|Archexin AKT1 common genes common pathways GO:0010033| response to organic substance UGT1A1;AKT1 36718:[DB06817 DB12629] DB06817|Raltegravir pol;UGT1A1 DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36719:[DB06817 DB06240] DB06817|Raltegravir pol;UGT1A1 DB06240|Tariquidar ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 36720:[DB06817 DB07447] DB06817|Raltegravir pol;UGT1A1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0008202| steroid metabolic process AKR1D1;UGT1A1 GO:0007586| digestion UGT1A1;AKR1D1 36721:[DB06817 DB08729] DB06817|Raltegravir pol;UGT1A1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways GO:0008152| metabolic process PDE5A;UGT1A1 36722:[DB06817 DB11752] DB06817|Raltegravir pol;UGT1A1 DB11752|Bryostatin 1 CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36723:[DB06817 DB00498] DB06817|Raltegravir pol;UGT1A1 DB00498|Phenindione VKORC1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;VKORC1 36724:[DB06817 DB08878] DB06817|Raltegravir pol;UGT1A1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways 36725:[DB06817 DB14146] DB06817|Raltegravir pol;UGT1A1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 36726:[DB06817 DB14029] DB06817|Raltegravir pol;UGT1A1 DB14029|Furafylline CYP1A2 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 36727:[DB06817 DB09107] DB06817|Raltegravir pol;UGT1A1 DB09107|Methoxy polyethylene glycol-epoetin beta EPOR common genes common pathways 36728:[DB06817 DB00159] DB06817|Raltegravir pol;UGT1A1 DB00159|Icosapent PTGS2;PTGS1;PPARG;PPARD;FADS1;ACSL4;ACSL3;FFAR1;SLC8A1;TRPV1;PPARA;FABP7;ALB common genes common pathways GO:0031100| organ regeneration PPARG;UGT1A1 GO:0010033| response to organic substance PPARD;PPARG;PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0042493| response to drug PPARG;SLC8A1;PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;ACSL3;PPARG GO:0007584| response to nutrient UGT1A1;SLC8A1;ACSL4;ACSL3;PPARG GO:0008152| metabolic process UGT1A1;ACSL4;ACSL3 36729:[DB06817 DB04903] DB06817|Raltegravir pol;UGT1A1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways 36730:[DB06817 DB00727] DB06817|Raltegravir pol;UGT1A1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0008152| metabolic process UGT1A1;ALDH2 36731:[DB06817 DB13014] DB06817|Raltegravir pol;UGT1A1 DB13014|Hypericin GSTA1;GSTP1;ALB common genes common pathways GO:0045471| response to ethanol UGT1A1;GSTP1 GO:0008152| metabolic process UGT1A1;GSTA1;GSTP1 GO:0031100| organ regeneration UGT1A1;GSTP1 GO:0071385| cellular response to glucocorticoid stimulus GSTP1;UGT1A1 36732:[DB06817 DB12742] DB06817|Raltegravir pol;UGT1A1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0014070| response to organic cyclic compound RAD51;UGT1A1 GO:0031100| organ regeneration FLT3;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0042493| response to drug RET;UGT1A1;RAD51 36733:[DB06817 DB11915] DB06817|Raltegravir pol;UGT1A1 DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;UGT1A1;CYP3A5 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 36734:[DB06817 DB01579] DB06817|Raltegravir pol;UGT1A1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0042493| response to drug SLC6A2;UGT1A1;ADRA1A 36735:[DB06817 DB05964] DB06817|Raltegravir pol;UGT1A1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0042493| response to drug SLC6A4;DRD2;SLC6A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0045471| response to ethanol UGT1A1;DRD2 GO:0007584| response to nutrient UGT1A1;SLC6A4 36736:[DB06817 DB06663] DB06817|Raltegravir pol;UGT1A1 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0042594| response to starvation SSTR3;SSTR2;SSTR1;UGT1A1 GO:0007586| digestion SSTR1;SSTR2;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;SSTR2;SSTR3;SSTR5 GO:0071392| cellular response to estradiol stimulus UGT1A1;SSTR1;SSTR2;SSTR3 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0007584| response to nutrient SSTR1;SSTR2;UGT1A1 36737:[DB06817 DB00082] DB06817|Raltegravir pol;UGT1A1 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0042493| response to drug BCHE;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0032870| cellular response to hormone stimulus GHR;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCHE GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 36738:[DB06817 DB01861] DB06817|Raltegravir pol;UGT1A1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 36739:[DB06817 DB04557] DB06817|Raltegravir pol;UGT1A1 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes common pathways GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C9 GO:0007586| digestion UGT1A1;FABP2 36740:[DB06817 DB00870] DB06817|Raltegravir pol;UGT1A1 DB00870|Suprofen PTGS1;PTGS2;CYP2C9;UGT1A1;UGT2B7 common genes UGT1A1 common pathways GO:0042493| response to drug PTGS2;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:1904224| UGT1A1 GO:0007586| digestion UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process UGT2B7;UGT1A1;CYP2C9 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP2C9;UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT2B7;UGT1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0001889| liver development UGT1A1 GO:0008152| metabolic process UGT1A1;UGT2B7 GO:0071361| cellular response to ethanol UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042167| heme catabolic process UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 36741:[DB06817 DB00028] DB06817|Raltegravir pol;UGT1A1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways 36742:[DB06817 DB06196] DB06817|Raltegravir pol;UGT1A1 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways 36743:[DB06817 DB01246] DB06817|Raltegravir pol;UGT1A1 DB01246|Alimemazine HRH1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36744:[DB06817 DB01442] DB06817|Raltegravir pol;UGT1A1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;MAOB GO:0042493| response to drug UGT1A1;SLC6A2;MAOB;SLC6A3;HTR2A;SLC6A4 GO:0048545| response to steroid hormone stimulus MAOB;UGT1A1 GO:0010033| response to organic substance SLC6A4;UGT1A1 GO:0045471| response to ethanol UGT1A1;MAOB;SLC6A3 GO:0007584| response to nutrient SLC6A4;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 36745:[DB06817 DB00899] DB06817|Raltegravir pol;UGT1A1 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 GO:0032496| response to lipopolysaccharide UGT1A1;OPRM1 36746:[DB06817 DB13530] DB06817|Raltegravir pol;UGT1A1 DB13530|Mepindolol CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 36747:[DB06817 DB05199] DB06817|Raltegravir pol;UGT1A1 DB05199|LX1031 TPH1 common genes common pathways 36748:[DB06817 DB01103] DB06817|Raltegravir pol;UGT1A1 DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP3A5;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug ABCB1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008152| metabolic process PLA2G6;UGT1A1;PLA2G4A 36749:[DB06817 DB13165] DB06817|Raltegravir pol;UGT1A1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways 36750:[DB06817 DB03346] DB06817|Raltegravir pol;UGT1A1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0008202| steroid metabolic process UGT1A1;SULT1E1 GO:0008210| estrogen metabolic process SULT1E1;UGT1A1 36751:[DB06817 DB00686] DB06817|Raltegravir pol;UGT1A1 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways 36752:[DB06817 DB09093] DB06817|Raltegravir pol;UGT1A1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways 36753:[DB06817 DB06203] DB06817|Raltegravir pol;UGT1A1 DB06203|Alogliptin DPP4;CYP3A4;CYP2D6 common genes common pathways GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 36754:[DB06817 DB13443] DB06817|Raltegravir pol;UGT1A1 DB13443|Esatenolol CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process CYP2D6;UGT1A1 36755:[DB06817 DB05642] DB06817|Raltegravir pol;UGT1A1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;UGT1A1 GO:0045471| response to ethanol HTR3A;UGT1A1 36756:[DB06817 DB00245] DB06817|Raltegravir pol;UGT1A1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0042493| response to drug SLC6A3;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2D6 GO:0045471| response to ethanol UGT1A1;SLC6A3 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1;CYP2C19 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1 36757:[DB06817 DB14070] DB06817|Raltegravir pol;UGT1A1 DB14070|HM-30181 ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 36758:[DB06817 DB03477] DB06817|Raltegravir pol;UGT1A1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 36759:[DB06817 DB11156] DB06817|Raltegravir pol;UGT1A1 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways 36760:[DB06817 DB08935] DB06817|Raltegravir pol;UGT1A1 DB08935|Obinutuzumab MS4A1 common genes common pathways 36761:[DB06817 DB05131] DB06817|Raltegravir pol;UGT1A1 DB05131|TTP889 F9 common genes common pathways 36762:[DB06817 DB09257] DB06817|Raltegravir pol;UGT1A1 DB09257|Gimeracil DPYD common genes common pathways 36763:[DB06817 DB09546] DB06817|Raltegravir pol;UGT1A1 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0042493| response to drug UGT1A1;SLC6A2 36764:[DB06817 DB08964] DB06817|Raltegravir pol;UGT1A1 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;PTGER2 36765:[DB06817 DB00981] DB06817|Raltegravir pol;UGT1A1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0045471| response to ethanol CHRNB2;UGT1A1 36766:[DB06817 DB08496] DB06817|Raltegravir pol;UGT1A1 DB08496|(R)-warfarin CYP2C8;CYP2C9;CYP2C18;CYP2C19;CYP1A2;CYP1A1;CYP3A4;ALB common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2C9;UGT1A1;CYP2C19;CYP2C8;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;UGT1A1;CYP2C8;CYP2C19;CYP1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;CYP1A1 GO:0042493| response to drug CYP1A2;CYP1A1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C19;CYP1A1 36767:[DB06817 DB08879] DB06817|Raltegravir pol;UGT1A1 DB08879|Belimumab TNFSF13B common genes common pathways 36768:[DB06817 DB02134] DB06817|Raltegravir pol;UGT1A1 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 36769:[DB06817 DB05804] DB06817|Raltegravir pol;UGT1A1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A7 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 36770:[DB06817 DB13074] DB06817|Raltegravir pol;UGT1A1 DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36771:[DB06817 DB11133] DB06817|Raltegravir pol;UGT1A1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0042493| response to drug PPARG;UGT1A1;SREBF1;PTGS2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1;PPARG GO:0031100| organ regeneration PPARG;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;SREBF1 GO:0007584| response to nutrient UGT1A1;PPARG GO:0014070| response to organic cyclic compound PTGS2;SREBF1;UGT1A1;PPARG GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36772:[DB06817 DB01325] DB06817|Raltegravir pol;UGT1A1 DB01325|Quinethazone CA1;CA2;SLC12A1;SLC12A2;SLC12A3 common genes common pathways GO:0010033| response to organic substance CA2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 36773:[DB06817 DB01353] DB06817|Raltegravir pol;UGT1A1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways 36774:[DB06817 DB00395] DB06817|Raltegravir pol;UGT1A1 DB00395|Carisoprodol GABRA1;GABRB2;GABRG2;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19 36775:[DB06817 DB12301] DB06817|Raltegravir pol;UGT1A1 DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes pol common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A5;UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36776:[DB06817 DB13174] DB06817|Raltegravir pol;UGT1A1 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1;CYP1A2;CYP2D6;CYP3A4 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A5;UGT1A1;CYP1A2;CYP2D6;CYP2C9;CYP3A4 GO:0042493| response to drug UGT1A1;CYP2E1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 36777:[DB06817 DB05099] DB06817|Raltegravir pol;UGT1A1 DB05099|Ancrod FGA common genes common pathways 36778:[DB06817 DB11359] DB06817|Raltegravir pol;UGT1A1 DB11359|Guaiacol ALB common genes common pathways 36779:[DB06817 DB11738] DB06817|Raltegravir pol;UGT1A1 DB11738|Rilmenidine ADRA2A common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 36780:[DB06817 DB05879] DB06817|Raltegravir pol;UGT1A1 DB05879|AME-527 TNF common genes common pathways GO:0010033| response to organic substance UGT1A1;TNF GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF 36781:[DB06817 DB00588] DB06817|Raltegravir pol;UGT1A1 DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP3A5;CYP3A7;CYP2C8;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008152| metabolic process UGT1A1;PLA2G4A 36782:[DB06817 DB08828] DB06817|Raltegravir pol;UGT1A1 DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;UGT1A1;CYP2C9;CYP3A4 GO:0006953| acute-phase response ORM1;UGT1A1 GO:0042493| response to drug UGT1A1;ABCG2;ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2C19;UGT1A1 36783:[DB06817 DB07449] DB06817|Raltegravir pol;UGT1A1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 36784:[DB06817 DB00388] DB06817|Raltegravir pol;UGT1A1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ADRA1A;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 36785:[DB06817 DB01401] DB06817|Raltegravir pol;UGT1A1 DB01401|Choline magnesium trisalicylate PTGS1;PTGS2 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 36786:[DB06817 DB05889] DB06817|Raltegravir pol;UGT1A1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 36787:[DB06817 DB00719] DB06817|Raltegravir pol;UGT1A1 DB00719|Azatadine HRH1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36788:[DB06817 DB01013] DB06817|Raltegravir pol;UGT1A1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0042493| response to drug UGT1A1;CYP1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A1;UGT1A1 GO:0008202| steroid metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0010033| response to organic substance CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1;CYP3A4 GO:0001889| liver development UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 36789:[DB06817 DB06235] DB06817|Raltegravir pol;UGT1A1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:1904224| UGT1A1;UGT1A9 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT2B7;UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;UGT1A9;CYP1A2 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0008152| metabolic process UGT1A1;UGT2B7;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A9;UGT1A1;UGT2B7 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 36790:[DB06817 DB04971] DB06817|Raltegravir pol;UGT1A1 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0007584| response to nutrient PPARG;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PPARG GO:0010033| response to organic substance UGT1A1;PPARG GO:0031100| organ regeneration UGT1A1;PPARG GO:0042493| response to drug UGT1A1;PPARG GO:0042594| response to starvation UGT1A1;PPARG 36791:[DB06817 DB14066] DB06817|Raltegravir pol;UGT1A1 DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug ABCB1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36792:[DB06817 DB00703] DB06817|Raltegravir pol;UGT1A1 DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways GO:0045471| response to ethanol CYP2E1;CA3;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2E1;CYP3A4;CYP2D6 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0017144| drug metabolic process CYP2E1;CYP2C19;UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2E1;CYP3A4;CYP2D6 GO:0010033| response to organic substance CA2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP2E1 36793:[DB06817 DB00337] DB06817|Raltegravir pol;UGT1A1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0007584| response to nutrient UGT1A1;MTOR GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36794:[DB06817 DB06470] DB06817|Raltegravir pol;UGT1A1 DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP2B6;CYP2A6;CYP3A4 GO:0008202| steroid metabolic process CYP2B6;CYP3A4;CYP2A6;CYP2C19;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 36795:[DB06817 DB01042] DB06817|Raltegravir pol;UGT1A1 DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways 36796:[DB06817 DB05297] DB06817|Raltegravir pol;UGT1A1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0042493| response to drug BCL2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;BCL2 GO:0051384| response to glucocorticoid stimulus UGT1A1;BCL2 36797:[DB06817 DB00009] DB06817|Raltegravir pol;UGT1A1 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 36798:[DB06817 DB08890] DB06817|Raltegravir pol;UGT1A1 DB08890|Linaclotide GUCY2C common genes common pathways GO:0007586| digestion GUCY2C;UGT1A1 36799:[DB06817 DB07285] DB06817|Raltegravir pol;UGT1A1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 36800:[DB06817 DB01628] DB06817|Raltegravir pol;UGT1A1 DB01628|Etoricoxib PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;UGT1A1;PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2;UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP2E1;CYP2C19;UGT1A1;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;CYP3A4;CYP2E1;CYP2C19;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 36801:[DB06817 DB01002] DB06817|Raltegravir pol;UGT1A1 DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;UGT1A1 36802:[DB06817 DB04842] DB06817|Raltegravir pol;UGT1A1 DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2A;DRD2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol DRD2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36803:[DB06817 DB00509] DB06817|Raltegravir pol;UGT1A1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways 36804:[DB06817 DB01392] DB06817|Raltegravir pol;UGT1A1 DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0045471| response to ethanol DRD2;UGT1A1;DRD3;HTR1B GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;KCNJ8 GO:0042493| response to drug HTR2B;UGT1A1;KCNJ11;DRD2;HTR2A;HTR1B;DRD3;HTR2C GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 36805:[DB06817 DB01809] DB06817|Raltegravir pol;UGT1A1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0042493| response to drug UGT1A1;RET 36806:[DB06817 DB00833] DB06817|Raltegravir pol;UGT1A1 DB00833|Cefaclor MPO;SLC15A1;SLC15A2;SLC22A8;ABCB11 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;MPO GO:0007586| digestion UGT1A1;SLC15A1 36807:[DB06817 DB00591] DB06817|Raltegravir pol;UGT1A1 DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0014070| response to organic cyclic compound ANXA1;UGT1A1 GO:0051384| response to glucocorticoid stimulus ANXA3;UGT1A1;ANXA1 GO:0043086| negative regulation of catalytic activity ANXA4;ANXA2;ANXA3;UGT1A1;ANXA5 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0010033| response to organic substance UGT1A1;ANXA5 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0031100| organ regeneration UGT1A1;ANXA3 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug ANXA1;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;UGT1A1;NR3C1 36808:[DB06817 DB01549] DB06817|Raltegravir pol;UGT1A1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0042493| response to drug DRD2;UGT1A1 GO:0045471| response to ethanol DRD2;GRIN3A;UGT1A1 36809:[DB06817 DB06788] DB06817|Raltegravir pol;UGT1A1 DB06788|Histrelin GNRHR common genes common pathways 36810:[DB06817 DB05271] DB06817|Raltegravir pol;UGT1A1 DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0045471| response to ethanol DRD2;UGT1A1;DRD3 GO:0042493| response to drug DRD3;UGT1A1;DRD2;DRD1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 36811:[DB06817 DB12483] DB06817|Raltegravir pol;UGT1A1 DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A7;UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1 GO:0001889| liver development UGT1A1;PIK3CA GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36812:[DB06817 DB11693] DB06817|Raltegravir pol;UGT1A1 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 36813:[DB06817 DB06834] DB06817|Raltegravir pol;UGT1A1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways 36814:[DB06817 DB06612] DB06817|Raltegravir pol;UGT1A1 DB06612|Mepolizumab IL5 common genes common pathways 36815:[DB06817 DB05152] DB06817|Raltegravir pol;UGT1A1 DB05152|NGX267 CHRM1 common genes common pathways 36816:[DB06817 DB11529] DB06817|Raltegravir pol;UGT1A1 DB11529|Melengestrol CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36817:[DB06817 DB01931] DB06817|Raltegravir pol;UGT1A1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways GO:0045471| response to ethanol UGT1A1;GRIN1 36818:[DB06817 DB02659] DB06817|Raltegravir pol;UGT1A1 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;ABCC2 GO:0042493| response to drug ABCC1;UGT1A1;FECH;ABCC2;ABCB1;ABCC4 GO:0048545| response to steroid hormone stimulus ABCC2;UGT1A1 GO:0010033| response to organic substance UGT1A1;ABCC4 GO:0045471| response to ethanol UGT1A1;FECH GO:0008152| metabolic process CES1;UGT1A1 GO:0032870| cellular response to hormone stimulus ABCC2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;ABCC4 GO:0007584| response to nutrient UGT1A1;COX4I1 36819:[DB06817 DB05110] DB06817|Raltegravir pol;UGT1A1 DB05110|VIR201 IFNG common genes common pathways 36820:[DB06817 DB04899] DB06817|Raltegravir pol;UGT1A1 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways 36821:[DB06817 DB00432] DB06817|Raltegravir pol;UGT1A1 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways GO:0042493| response to drug TYMS;UGT1A1 GO:0008152| metabolic process UGT1A1;TYMP GO:0045471| response to ethanol TYMS;UGT1A1 GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS 36822:[DB06817 DB12116] DB06817|Raltegravir pol;UGT1A1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways 36823:[DB06817 DB02597] DB06817|Raltegravir pol;UGT1A1 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways 36824:[DB06817 DB02309] DB06817|Raltegravir pol;UGT1A1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways GO:0031100| organ regeneration UGT1A1;ATIC GO:0008152| metabolic process UGT1A1;ATIC 36825:[DB06817 DB06429] DB06817|Raltegravir pol;UGT1A1 DB06429|Talnetant TACR3 common genes common pathways 36826:[DB06817 DB04932] DB06817|Raltegravir pol;UGT1A1 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0042493| response to drug ADORA2A;UGT1A1 36827:[DB06817 DB14543] DB06817|Raltegravir pol;UGT1A1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0008152| metabolic process HSD3B1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032870| cellular response to hormone stimulus CYP11B1;UGT1A1;CYP11B2 GO:0051384| response to glucocorticoid stimulus UGT1A1;ANXA1;HSD11B2 GO:0014070| response to organic cyclic compound UGT1A1;ANXA1 GO:0071385| cellular response to glucocorticoid stimulus ANXA1;NR3C1;UGT1A1 GO:0042493| response to drug UGT1A1;ABCG2;ABCB1;HSD11B2;ANXA1 GO:0048545| response to steroid hormone stimulus HSD11B2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP2C8;UGT1A1;CYP11B2 36828:[DB06817 DB07641] DB06817|Raltegravir pol;UGT1A1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways 36829:[DB06817 DB04235] DB06817|Raltegravir pol;UGT1A1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0045471| response to ethanol ABAT;UGT1A1 GO:0042493| response to drug ABAT;UGT1A1 36830:[DB06817 DB05541] DB06817|Raltegravir pol;UGT1A1 DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0042493| response to drug SCN11A;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2B6;CYP2C9;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP3A4;CYP2C9;CYP2B6 36831:[DB06817 DB01164] DB06817|Raltegravir pol;UGT1A1 DB01164|Calcium Chloride S100A13 common genes common pathways 36832:[DB06817 DB06678] DB06817|Raltegravir pol;UGT1A1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0042493| response to drug UGT1A1;HTR2B;HTR2A;HTR2C GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 36833:[DB06817 DB09283] DB06817|Raltegravir pol;UGT1A1 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0008152| metabolic process UGT1A1;PDE11A;PDE5A;PDE2A;PDE10A GO:0042493| response to drug PDE3A;UGT1A1 36834:[DB06817 DB00740] DB06817|Raltegravir pol;UGT1A1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP1A1;UGT1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP1A1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP1A2 GO:0042493| response to drug UGT1A1;ABCG2;CYP1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;UGT1A1 36835:[DB06817 DB09317] DB06817|Raltegravir pol;UGT1A1 DB09317|Synthetic Conjugated Estrogens, A ESR1;CYP3A4 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36836:[DB06817 DB01482] DB06817|Raltegravir pol;UGT1A1 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 36837:[DB06817 DB11772] DB06817|Raltegravir pol;UGT1A1 DB11772|Pilaralisib PIK3CA common genes common pathways GO:0001889| liver development UGT1A1;PIK3CA 36838:[DB06817 DB14067] DB06817|Raltegravir pol;UGT1A1 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 36839:[DB06817 DB11994] DB06817|Raltegravir pol;UGT1A1 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;UGT1A1;CYP2E1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1;CYP2E1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP2E1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4;CYP1A2;CYP2C9;CYP2D6 36840:[DB06817 DB04841] DB06817|Raltegravir pol;UGT1A1 DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP1A1;UGT1A1;CYP2C9;CYP2D6;CYP1A2;CYP2A6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP1A2;UGT1A1;CYP1A1 GO:0010033| response to organic substance CYP1A2;CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;UGT1A1 GO:0042493| response to drug CYP1A1;UGT1A1;CYP1A2 GO:0032870| cellular response to hormone stimulus CACNA1H;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;UGT1A1;CYP1A1 GO:0001889| liver development CYP1A1;UGT1A1 36841:[DB06817 DB05903] DB06817|Raltegravir pol;UGT1A1 DB05903|KOS-1584 CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36842:[DB06817 DB00491] DB06817|Raltegravir pol;UGT1A1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways GO:0008152| metabolic process UGT1A1;GANC;GAA;MGAM;AMY2A;GANAB 36843:[DB06817 DB09008] DB06817|Raltegravir pol;UGT1A1 DB09008|Cefaloridine SLC22A6;SLC22A8 common genes common pathways 36844:[DB06817 DB00853] DB06817|Raltegravir pol;UGT1A1 DB00853|Temozolomide CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36845:[DB06817 DB04970] DB06817|Raltegravir pol;UGT1A1 DB04970|Lesopitron HTR1A common genes common pathways 36846:[DB06817 DB14068] DB06817|Raltegravir pol;UGT1A1 DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0042493| response to drug ABCB1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36847:[DB06817 DB01285] DB06817|Raltegravir pol;UGT1A1 DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CRH;UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug CRH;UGT1A1 GO:0032496| response to lipopolysaccharide CYP27B1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0045471| response to ethanol CRH;UGT1A1 GO:0008152| metabolic process HSD3B2;UGT1A1 36848:[DB06817 DB00015] DB06817|Raltegravir pol;UGT1A1 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 36849:[DB06817 DB09013] DB06817|Raltegravir pol;UGT1A1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process UGT1A1;CYP2D6 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6 36850:[DB06817 DB09302] DB06817|Raltegravir pol;UGT1A1 DB09302|Alirocumab PCSK9 common genes common pathways GO:0001889| liver development UGT1A1;PCSK9 GO:0008202| steroid metabolic process PCSK9;UGT1A1 36851:[DB06817 DB13044] DB06817|Raltegravir pol;UGT1A1 DB13044|Gossypol BCL2L1 common genes common pathways 36852:[DB06817 DB12789] DB06817|Raltegravir pol;UGT1A1 DB12789|Dinoprost PTGDR2 common genes common pathways 36853:[DB06817 DB01852] DB06817|Raltegravir pol;UGT1A1 DB01852|Kaempherol UGT3A1 common genes common pathways GO:0008152| metabolic process UGT1A1;UGT3A1 36854:[DB06817 DB00894] DB06817|Raltegravir pol;UGT1A1 DB00894|Testolactone CYP19A1 common genes common pathways 36855:[DB06817 DB00447] DB06817|Raltegravir pol;UGT1A1 DB00447|Loracarbef SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 36856:[DB06817 DB00492] DB06817|Raltegravir pol;UGT1A1 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 36857:[DB06817 DB00986] DB06817|Raltegravir pol;UGT1A1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 36858:[DB06817 DB05443] DB06817|Raltegravir pol;UGT1A1 DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0045471| response to ethanol UGT1A1;OPRK1 36859:[DB06817 DB05098] DB06817|Raltegravir pol;UGT1A1 DB05098|Leptin LEPR common genes common pathways 36860:[DB06817 DB00217] DB06817|Raltegravir pol;UGT1A1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 36861:[DB06817 DB09101] DB06817|Raltegravir pol;UGT1A1 DB09101|Elvitegravir pol;CYP3A4 common genes pol common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36862:[DB06817 DB09344] DB06817|Raltegravir pol;UGT1A1 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways GO:0008152| metabolic process GCK;UGT1A1 36863:[DB06817 DB01090] DB06817|Raltegravir pol;UGT1A1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 36864:[DB06817 DB00361] DB06817|Raltegravir pol;UGT1A1 DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0042493| response to drug UGT1A1;ABCB1 36865:[DB06817 DB12140] DB06817|Raltegravir pol;UGT1A1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0051384| response to glucocorticoid stimulus IL6;TNF;UGT1A1 GO:0006953| acute-phase response UGT1A1;IL6 GO:0032496| response to lipopolysaccharide UGT1A1;IL1B GO:0010033| response to organic substance TNF;UGT1A1 36866:[DB06817 DB01291] DB06817|Raltegravir pol;UGT1A1 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways 36867:[DB06817 DB09262] DB06817|Raltegravir pol;UGT1A1 DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways GO:0045922| negative regulation of fatty acid metabolic process UGT1A4;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A4;UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A4;UGT1A1;CYP3A4 GO:0006953| acute-phase response ORM2;UGT1A1;ORM1 GO:1904224| UGT1A4;UGT1A1 GO:0007586| digestion CHRM3;UGT1A1 GO:0042167| heme catabolic process UGT1A1;UGT1A4 GO:0052695| cellular glucuronidation UGT1A4;UGT1A1 GO:0006789| bilirubin conjugation UGT1A4;UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008152| metabolic process UGT1A4;UGT1A1 36868:[DB06817 DB05294] DB06817|Raltegravir pol;UGT1A1 DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;EGFR GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0001889| liver development UGT1A1;EGFR GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1 GO:0017144| drug metabolic process UGT1A1;FMO1;CYP3A4 GO:0010033| response to organic substance UGT1A1;TEK GO:0032496| response to lipopolysaccharide UGT1A1;FMO1 GO:0042493| response to drug UGT1A1;ABCC1;ABCG2;RET GO:0006953| acute-phase response ORM1;UGT1A1 36869:[DB06817 DB04845] DB06817|Raltegravir pol;UGT1A1 DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36870:[DB06817 DB08575] DB06817|Raltegravir pol;UGT1A1 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways 36871:[DB06817 DB02852] DB06817|Raltegravir pol;UGT1A1 DB02852|Domoic Acid GRIK2 common genes common pathways 36872:[DB06817 DB06413] DB06817|Raltegravir pol;UGT1A1 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2C19;UGT1A1 GO:0045471| response to ethanol UGT1A1;SLC6A3 GO:0014070| response to organic cyclic compound SLC6A3;UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;SLC6A3;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2B6;CYP1A2;CYP2C19;UGT1A1;CYP3A5 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4;CYP1A2;CYP2C9;CYP2B6 36873:[DB06817 DB00542] DB06817|Raltegravir pol;UGT1A1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 GO:0042493| response to drug MTHFR;UGT1A1 GO:0008152| metabolic process MTHFR;UGT1A1 36874:[DB06817 DB12391] DB06817|Raltegravir pol;UGT1A1 DB12391|Sagopilone CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36875:[DB06817 DB13261] DB06817|Raltegravir pol;UGT1A1 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 36876:[DB06817 DB01093] DB06817|Raltegravir pol;UGT1A1 DB01093|Dimethyl sulfoxide CYP2C19;CYP2D6;CYP3A4;TTR common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1;CYP2C19 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP2D6;CYP3A4 36877:[DB06817 DB06116] DB06817|Raltegravir pol;UGT1A1 DB06116|Eldelumab CXCL10 common genes common pathways GO:0032496| response to lipopolysaccharide CXCL10;UGT1A1 36878:[DB06817 DB04834] DB06817|Raltegravir pol;UGT1A1 DB04834|Rapacuronium CHRM2 common genes common pathways 36879:[DB06817 DB08870] DB06817|Raltegravir pol;UGT1A1 DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;TNFRSF8 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36880:[DB06817 DB01785] DB06817|Raltegravir pol;UGT1A1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0008202| steroid metabolic process FDPS;UGT1A1;IDI1 36881:[DB06817 DB03683] DB06817|Raltegravir pol;UGT1A1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 36882:[DB06817 DB01413] DB06817|Raltegravir pol;UGT1A1 DB01413|Cefepime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 36883:[DB06817 DB09212] DB06817|Raltegravir pol;UGT1A1 DB09212|Loxoprofen PTGS2;PTGS1;PTGS1;PTGS2 common genes common pathways GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 36884:[DB06817 DB06089] DB06817|Raltegravir pol;UGT1A1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways 36885:[DB06817 DB00012] DB06817|Raltegravir pol;UGT1A1 DB00012|Darbepoetin alfa EPOR common genes common pathways 36886:[DB06817 DB09119] DB06817|Raltegravir pol;UGT1A1 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes UGT1A1 common pathways GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0042493| response to drug UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:1904224| UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0031100| organ regeneration UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0051552| flavone metabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 36887:[DB06817 DB03929] DB06817|Raltegravir pol;UGT1A1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0071361| cellular response to ethanol UGT1A1;GLRA1 GO:0045471| response to ethanol UGT1A1;GRIN1 GO:0043086| negative regulation of catalytic activity UGT1A1;SERPINB3 36888:[DB06817 DB00201] DB06817|Raltegravir pol;UGT1A1 DB00201|Caffeine ADORA1;ADORA2A;PDE4B;RYR1;PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B;PRKDC;PIK3CD;PIK3CA;PIK3CB;ITPR1;ITPR2;ITPR3;ATM;CYP3A5;CYP1A2;CYP3A7;CYP3A4;CYP2E1;CYP2C8;CYP2C9;CYP1A1;CYP1B1;CYP2D6;ABCB1 common genes common pathways GO:0010033| response to organic substance CYP1A2;CYP1A1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A1;CYP3A5;CYP2E1;CYP3A7;CYP1B1;CYP3A4;CYP2C9;CYP2D6;CYP1A2 GO:0017144| drug metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;UGT1A1;CYP2C8;CYP1A1;CYP2E1 GO:0042493| response to drug CYP2E1;PDE3A;CYP1A1;UGT1A1;ADORA2A;CYP1A2;ABCB1 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2 GO:0001889| liver development UGT1A1;CYP1A1;PIK3CA GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP1A1;CYP3A4;CYP1A2;CYP2D6 GO:0071361| cellular response to ethanol UGT1A1;ITPR2 GO:0008152| metabolic process PDE10A;PDE5A;PDE2A;PDE11A;UGT1A1 36889:[DB06817 DB00972] DB06817|Raltegravir pol;UGT1A1 DB00972|Azelastine HRH1;CYP1A2;CYP3A4;CYP2C19;CYP1A1;CYP3A5;CYP2C9;CYP2C8;CYP2D6;CYP2A6;CYP2B6;CYP2E1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP3A5;CYP1A1;CYP2C19;CYP2C8;UGT1A1;CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP2A6;CYP3A4 GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;CYP1A1;CYP2E1;CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP2B6;CYP1A2 GO:0010033| response to organic substance CYP1A2;CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;UGT1A1 GO:0042493| response to drug CYP1A2;ABCB1;CYP2E1;CYP1A1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP1A1;CYP2E1;CYP3A4;CYP2D6;CYP1A2 36890:[DB06817 DB12455] DB06817|Raltegravir pol;UGT1A1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 36891:[DB06817 DB00774] DB06817|Raltegravir pol;UGT1A1 DB00774|Hydroflumethiazide SLC12A1;CA1;CA2;CA4;CA9;CA12;ATP1A1;KCNMA1 common genes common pathways GO:0042493| response to drug UGT1A1;ATP1A1;CA9 GO:0048545| response to steroid hormone stimulus CA2;UGT1A1 GO:0010033| response to organic substance CA2;UGT1A1 36892:[DB06817 DB04575] DB06817|Raltegravir pol;UGT1A1 DB04575|Quinestrol ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 36893:[DB06817 DB00402] DB06817|Raltegravir pol;UGT1A1 DB00402|Eszopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug GABRG3;TSPO;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C8;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C9;TSPO;CYP3A4 36894:[DB06817 DB01567] DB06817|Raltegravir pol;UGT1A1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 36895:[DB06817 DB00480] DB06817|Raltegravir pol;UGT1A1 DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 common genes common pathways GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36896:[DB06817 DB00771] DB06817|Raltegravir pol;UGT1A1 DB00771|Clidinium CHRM1 common genes common pathways 36897:[DB06817 DB00700] DB06817|Raltegravir pol;UGT1A1 DB00700|Eplerenone NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP11B2 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0032870| cellular response to hormone stimulus CYP11B2;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP3A5;CYP11B2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36898:[DB06817 DB09214] DB06817|Raltegravir pol;UGT1A1 DB09214|Dexketoprofen PTGS1;PTGS2;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 36899:[DB06817 DB00659] DB06817|Raltegravir pol;UGT1A1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0042493| response to drug GRIN2A;GABRG3;UGT1A1 GO:0045471| response to ethanol GRIN2B;GRIN2A;GRIN1;UGT1A1;GRIN3A 36900:[DB06817 DB09043] DB06817|Raltegravir pol;UGT1A1 DB09043|Albiglutide GLP1R common genes common pathways 36901:[DB06817 DB01608] DB06817|Raltegravir pol;UGT1A1 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0042493| response to drug UGT1A1;DRD1 36902:[DB06817 DB06719] DB06817|Raltegravir pol;UGT1A1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways 36903:[DB06817 DB01119] DB06817|Raltegravir pol;UGT1A1 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0010033| response to organic substance UGT1A1;CA2 GO:0048545| response to steroid hormone stimulus UGT1A1;CA2 GO:0042493| response to drug ATP1A1;KCNJ11;UGT1A1 36904:[DB06817 DB00026] DB06817|Raltegravir pol;UGT1A1 DB00026|Anakinra IL1R1 common genes common pathways 36905:[DB06817 DB04552] DB06817|Raltegravir pol;UGT1A1 DB04552|Niflumic Acid PLA2G1B;PTGS2;CLCNKA;PTGS1;PLA2G4A;UGT1A9;UGT1A9;SLC16A7;SLC16A1 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:1904224| UGT1A9;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1 GO:0017144| drug metabolic process UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A9 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A9;PLA2G4A GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9 GO:0052695| cellular glucuronidation UGT1A9;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 36906:[DB06817 DB05992] DB06817|Raltegravir pol;UGT1A1 DB05992|Plinabulin TNF common genes common pathways GO:0010033| response to organic substance UGT1A1;TNF GO:0051384| response to glucocorticoid stimulus UGT1A1;TNF 36907:[DB06817 DB00184] DB06817|Raltegravir pol;UGT1A1 DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;MAOB;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1;MAOB;CYP1A1;CYP2E1 GO:0008202| steroid metabolic process CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP2A6;CYP3A4;CYP2E1;CYP1A1;CYP2C19;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP2A6;CYP3A4;CYP2E1;CYP1A1;CYP2C19;CYP2C8;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0045471| response to ethanol CHRNB2;MAOB;CYP2E1;UGT1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;CYP3A4;CYP2E1;CYP1A1;CYP2C19;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;UGT1A1 36908:[DB06817 DB06777] DB06817|Raltegravir pol;UGT1A1 DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways GO:0052695| cellular glucuronidation UGT1A1;UGT2B7 GO:0008152| metabolic process UGT1A1;UGT2B7 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;UGT2B7;AKR1C2;CYP3A4;NR1I2 GO:0007586| digestion AKR1C2;UGT1A1 36909:[DB06817 DB08479] DB06817|Raltegravir pol;UGT1A1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug TYMS;UGT1A1 GO:0045471| response to ethanol TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS 36910:[DB06817 DB04630] DB06817|Raltegravir pol;UGT1A1 DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0008202| steroid metabolic process CYP17A1;CYP11B1;UGT1A1;CYP11B2;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0032870| cellular response to hormone stimulus CYP11B2;UGT1A1;CYP11B1 36911:[DB06817 DB05969] DB06817|Raltegravir pol;UGT1A1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways 36912:[DB06817 DB00809] DB06817|Raltegravir pol;UGT1A1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 36913:[DB06817 DB00648] DB06817|Raltegravir pol;UGT1A1 DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;CYP11B1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP11B1;FDX1;UGT1A1;CYP3A4 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36914:[DB06817 DB02303] DB06817|Raltegravir pol;UGT1A1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways 36915:[DB06817 DB00004] DB06817|Raltegravir pol;UGT1A1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways 36916:[DB06817 DB05461] DB06817|Raltegravir pol;UGT1A1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug HTR2B;UGT1A1 36917:[DB06817 DB02901] DB06817|Raltegravir pol;UGT1A1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0008210| estrogen metabolic process UGT1A1;HSD17B1 GO:0042493| response to drug UGT1A1;ABCB1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP17A1;CYP11A1 36918:[DB06817 DB06710] DB06817|Raltegravir pol;UGT1A1 DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2B6;UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2B6 36919:[DB06817 DB04838] DB06817|Raltegravir pol;UGT1A1 DB04838|Cyclandelate CACNA2D1;CES1;CYP3A4 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0008152| metabolic process CES1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36920:[DB06817 DB05905] DB06817|Raltegravir pol;UGT1A1 DB05905|TD-2749 HTR4 common genes common pathways 36921:[DB06817 DB07477] DB06817|Raltegravir pol;UGT1A1 DB07477|Felbinac CTSL common genes common pathways 36922:[DB06817 DB04070] DB06817|Raltegravir pol;UGT1A1 DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36923:[DB06817 DB00807] DB06817|Raltegravir pol;UGT1A1 DB00807|Proparacaine SCN10A common genes common pathways 36924:[DB06817 DB01972] DB06817|Raltegravir pol;UGT1A1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0031100| organ regeneration ATIC;UGT1A1 GO:0008152| metabolic process PDE5A;ATIC;UGT1A1 36925:[DB06817 DB05662] DB06817|Raltegravir pol;UGT1A1 DB05662|NP-50301 ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 36926:[DB06817 DB07637] DB06817|Raltegravir pol;UGT1A1 DB07637|Dibromotyrosine EPOR common genes common pathways 36927:[DB06817 DB06791] DB06817|Raltegravir pol;UGT1A1 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus SSTR2;UGT1A1;SSTR5 GO:0007586| digestion UGT1A1;SSTR2 GO:0042594| response to starvation SSTR2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0071392| cellular response to estradiol stimulus SSTR2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0007584| response to nutrient SSTR2;UGT1A1 36928:[DB06817 DB01622] DB06817|Raltegravir pol;UGT1A1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0042493| response to drug UGT1A1;HTR2A;DRD1;DRD2;ADRA1A GO:0045471| response to ethanol DRD2;UGT1A1 36929:[DB06817 DB09286] DB06817|Raltegravir pol;UGT1A1 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0045471| response to ethanol DRD2;UGT1A1;DRD3 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug DRD1;HTR2A;DRD2;ADRA1A;HTR2B;UGT1A1;DRD3 36930:[DB06817 DB05767] DB06817|Raltegravir pol;UGT1A1 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways GO:0032496| response to lipopolysaccharide NFKB2;UGT1A1;IL1B GO:0006953| acute-phase response IL6;UGT1A1 GO:0010033| response to organic substance UGT1A1;TNF GO:0051384| response to glucocorticoid stimulus IL6;TNF;UGT1A1 36931:[DB06817 DB06820] DB06817|Raltegravir pol;UGT1A1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP1A2;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP2D6;CYP2C9 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 36932:[DB06817 DB01320] DB06817|Raltegravir pol;UGT1A1 DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0008152| metabolic process UGT1A6;UGT1A1;UGT1A9 GO:0051552| flavone metabolic process UGT1A9;UGT1A1 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP2D6;CYP1A2;CYP3A4 GO:0052695| cellular glucuronidation UGT1A1;UGT1A6;UGT1A9 GO:2001030| negative regulation of cellular glucuronidation UGT1A6;UGT1A1;UGT1A9 GO:0017144| drug metabolic process UGT1A6;CYP2C19;UGT1A1;CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP3A4;UGT1A9 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;CYP2C9;CYP2D6;CYP1A2;UGT1A1;CYP2C19 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A6;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A1;UGT1A6 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A6;UGT1A1 GO:1904224| UGT1A9;UGT1A1;UGT1A6 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 36933:[DB06817 DB00871] DB06817|Raltegravir pol;UGT1A1 DB00871|Terbutaline ADRB2;ADRB3;ADRB1;BCHE common genes common pathways GO:0007584| response to nutrient UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 GO:0042493| response to drug BCHE;UGT1A1 36934:[DB06817 DB00933] DB06817|Raltegravir pol;UGT1A1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0045471| response to ethanol UGT1A1;DRD2 GO:0042493| response to drug UGT1A1;DRD2;HTR2A GO:0017144| drug metabolic process CYP2D6;UGT1A1 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 36935:[DB06817 DB00500] DB06817|Raltegravir pol;UGT1A1 DB00500|Tolmetin PTGS2;PTGS1;TDO2;MPO;ALB;SLC22A6 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide MPO;UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 36936:[DB06817 DB00804] DB06817|Raltegravir pol;UGT1A1 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A1 GO:0010033| response to organic substance UGT1A1;CYP1A1 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1 GO:0042493| response to drug CYP1A1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A1;UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 36937:[DB06817 DB00223] DB06817|Raltegravir pol;UGT1A1 DB00223|Diflorasone NR3C1 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 36938:[DB06817 DB01388] DB06817|Raltegravir pol;UGT1A1 DB01388|Mibefradil CACNA1G;CACNA1H;CACNA1C;CACNA1D;CACNA1F;CACNA1I;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP1A1;ABCB1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;UGT1A1 GO:0032870| cellular response to hormone stimulus CYP11B2;CACNA1H;UGT1A1;CYP11B1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;UGT1A1;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1 GO:0017144| drug metabolic process UGT1A1;CYP1A1;CYP3A4;CYP2D6;CYP1A2 GO:0008202| steroid metabolic process CYP3A7;CYP11B1;CYP3A5;CYP1A1;CYP11B2;UGT1A1;CYP1A2;CYP2D6;CYP3A4 GO:0042493| response to drug CYP1A1;UGT1A1;CYP1A2;ABCB1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;CYP1A1 36939:[DB06817 DB00106] DB06817|Raltegravir pol;UGT1A1 DB00106|Abarelix GNRHR common genes common pathways 36940:[DB06817 DB14062] DB06817|Raltegravir pol;UGT1A1 DB14062|Concanamycin A ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 36941:[DB06817 DB09118] DB06817|Raltegravir pol;UGT1A1 DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;CYP1A2;CYP2C19;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;LDHA;UGT1A1 GO:0007584| response to nutrient LDHA;UGT1A1 GO:0042493| response to drug UGT1A1;LDHA;CYP1A2;GABRG3 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;CYP1A2;CYP2C19;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;UGT1A1;CYP2C19 36942:[DB06817 DB04787] DB06817|Raltegravir pol;UGT1A1 DB04787|Tanaproget PGR common genes common pathways 36943:[DB06817 DB01116] DB06817|Raltegravir pol;UGT1A1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0042493| response to drug BCHE;UGT1A1 GO:0007584| response to nutrient UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 36944:[DB06817 DB11943] DB06817|Raltegravir pol;UGT1A1 DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes UGT1A1 common pathways GO:0010033| response to organic substance UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1;UGT1A3 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A3 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2E1;CYP3A4;UGT1A3;CYP2C9 GO:0031100| organ regeneration UGT1A1 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;CYP2E1;UGT2B15;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0042493| response to drug CYP2E1;ABCG2;UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion UGT1A1 GO:1904224| UGT1A1;UGT1A3 GO:0032496| response to lipopolysaccharide UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A3 GO:0014070| response to organic cyclic compound UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1;UGT2B15;UGT1A3 GO:2001030| negative regulation of cellular glucuronidation UGT1A3;UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT2B15;UGT1A1;UGT1A3 GO:0045471| response to ethanol UGT1A1;CYP2E1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2E1;CYP3A4 GO:0051552| flavone metabolic process UGT1A1 36945:[DB06817 DB13975] DB06817|Raltegravir pol;UGT1A1 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C9;CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;CYP1A2;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP2D6;CYP1A2 36946:[DB06817 DB09327] DB06817|Raltegravir pol;UGT1A1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0045471| response to ethanol UGT1A1;TYMS GO:0014070| response to organic cyclic compound UGT1A1;TYMS GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS GO:0042493| response to drug UGT1A1;TYMS GO:0008202| steroid metabolic process UGT1A1;CYP2A6 GO:0017144| drug metabolic process CYP2A6;UGT1A1 36947:[DB06817 DB00042] DB06817|Raltegravir pol;UGT1A1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 36948:[DB06817 DB08744] DB06817|Raltegravir pol;UGT1A1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways 36949:[DB06817 DB04253] DB06817|Raltegravir pol;UGT1A1 DB04253|Tretazicar NQO2 common genes common pathways 36950:[DB06817 DB05246] DB06817|Raltegravir pol;UGT1A1 DB05246|Methsuximide CACNA1G;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19 GO:0008202| steroid metabolic process CYP2C19;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19 36951:[DB06817 DB05259] DB06817|Raltegravir pol;UGT1A1 DB05259|Glatiramer HLA-DRB1 common genes common pathways 36952:[DB06817 DB13955] DB06817|Raltegravir pol;UGT1A1 DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes UGT1A1 common pathways GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;CYP1A2 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion UGT1A1;FABP2 GO:0042493| response to drug CYP1A2;ABCB1;BECN1;CYP1A1;UGT1A1;ABCG2 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR2;ESR1;GPER1;UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1B1;CYP1A2;NR1I2;CYP2C9;UGT1A1;CYP2C8;CYP2C19;CYP3A7;CYP1A1;CYP3A5 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process CYP1A2;CYP2C9;CYP3A4;CYP1A1;UGT1A1;CYP2C19;CYP2C8 GO:0031100| organ regeneration UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1;CYP1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;UGT1A1;CYP2C19;CYP1A1 GO:0051552| flavone metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus NCOA2;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 36953:[DB06817 DB00546] DB06817|Raltegravir pol;UGT1A1 DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0042493| response to drug GABRG3;UGT1A1 GO:0017144| drug metabolic process CYP2C19;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;UGT1A1 36954:[DB06817 DB14700] DB06817|Raltegravir pol;UGT1A1 DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0006953| acute-phase response UGT1A1;F8 36955:[DB06817 DB01158] DB06817|Raltegravir pol;UGT1A1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;UGT1A1 36956:[DB06817 DB09381] DB06817|Raltegravir pol;UGT1A1 DB09381|Estrogens, esterified CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 36957:[DB06817 DB00418] DB06817|Raltegravir pol;UGT1A1 DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP2C19;UGT1A1 GO:0045471| response to ethanol GRIN1;GRIN3A;UGT1A1;GRIN2A;GRIN2B GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug GRIN2A;CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;CYP1A2;CYP2C19;CYP2C8;UGT1A1 GO:0017144| drug metabolic process CYP2C9;CYP1A2;CYP2C19;CYP2C8;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 36958:[DB06817 DB09095] DB06817|Raltegravir pol;UGT1A1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0043086| negative regulation of catalytic activity ANXA3;UGT1A1 GO:0051384| response to glucocorticoid stimulus ANXA3;UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;NR3C1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0031100| organ regeneration UGT1A1;ANXA3 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 36959:[DB06817 DB13345] DB06817|Raltegravir pol;UGT1A1 DB13345|Dihydroergocristine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD1;DRD5;DRD2;DRD3;DRD4;CYP3A4;ABCB11 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug HTR1B;DRD3;HTR2C;HTR2B;UGT1A1;DRD1;HTR2A;ADRA1A;DRD2 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0045471| response to ethanol HTR1B;DRD3;HTR3A;DRD2;UGT1A1 36960:[DB06817 DB06558] DB06817|Raltegravir pol;UGT1A1 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways GO:0014070| response to organic cyclic compound EDNRB;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;EDNRB 36961:[DB06817 DB13915] DB06817|Raltegravir pol;UGT1A1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways 36962:[DB06817 DB06623] DB06817|Raltegravir pol;UGT1A1 DB06623|Flupirtine ADRA2A common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A 36963:[DB06817 DB00428] DB06817|Raltegravir pol;UGT1A1 DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;CYP1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2E1;CYP1A2 GO:0001889| liver development UGT1A1;CYP1A1 GO:0045471| response to ethanol CYP2E1;UGT1A1 GO:0008152| metabolic process MGEA5;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP2E1;CYP1A2 GO:0017144| drug metabolic process CYP1A2;CYP1A1;CYP2E1;UGT1A1 GO:0010033| response to organic substance CYP1A1;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;UGT1A1;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;CYP2E1;CYP1A1;UGT1A1 36964:[DB06817 DB09244] DB06817|Raltegravir pol;UGT1A1 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 36965:[DB06817 DB00387] DB06817|Raltegravir pol;UGT1A1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways GO:0007586| digestion CHRM3;UGT1A1 36966:[DB06817 DB11718] DB06817|Raltegravir pol;UGT1A1 DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0001889| liver development CCND1;UGT1A1 GO:0045471| response to ethanol CCND1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;CYP2D6;UGT1A1;CYP2C19 GO:0014070| response to organic cyclic compound CCND1;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;CCND1 GO:0042493| response to drug UGT1A1;CCND1 GO:0010033| response to organic substance UGT1A1;CCND1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2D6;CYP3A4 GO:0048545| response to steroid hormone stimulus CCND1;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2D6;CYP2C19;UGT1A1 GO:0031100| organ regeneration UGT1A1;CCND1 36967:[DB06817 DB05133] DB06817|Raltegravir pol;UGT1A1 DB05133|VP025 IL1B common genes common pathways GO:0032496| response to lipopolysaccharide IL1B;UGT1A1 36968:[DB06817 DB03742] DB06817|Raltegravir pol;UGT1A1 DB03742|Compound 4-D ESR1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 36969:[DB06817 DB02709] DB06817|Raltegravir pol;UGT1A1 DB02709|Resveratrol NQO2;CSNK2A1;PTGS1;PTGS2;ALOX15;ALOX5;AHR;PI4K2B;ITGA5;ITGB3;APP;SNCA;ESR1;MTNR1A;MTNR1B;CLEC14A;NR1I2;NR1I3;SLC2A1;CBR1;PPARA;PPARG;AKT1;KHSRP;YARS;CYP1A2;CYP1A1;CYP1B1;CYP3A4;TTR;ALB common genes common pathways GO:0001889| liver development CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP3A4;CYP1A2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0007584| response to nutrient PPARG;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;CYP1A1;PPARG;CYP1A2 GO:0042594| response to starvation PPARG;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;SNCA;UGT1A1;CYP1A1;CYP1A2 GO:0008210| estrogen metabolic process CYP1B1;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1;SNCA;CYP1A1;PPARG;CYP1A2 GO:0017144| drug metabolic process CYP1A1;UGT1A1;CBR1;CYP1A2;CYP3A4 GO:0031100| organ regeneration PPARG;UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A1;CYP3A4;CYP1B1;CYP1A2;NR1I2 GO:0010033| response to organic substance PPARG;CYP1A2;PTGS2;AKT1;UGT1A1;CYP1A1 36970:[DB06817 DB01278] DB06817|Raltegravir pol;UGT1A1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;RAMP3 GO:0051384| response to glucocorticoid stimulus CALCR;UGT1A1 GO:0032870| cellular response to hormone stimulus RAMP2;UGT1A1 36971:[DB06817 DB05369] DB06817|Raltegravir pol;UGT1A1 DB05369|HZT-501 HRH2 common genes common pathways 36972:[DB06817 DB01348] DB06817|Raltegravir pol;UGT1A1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 36973:[DB06817 DB00961] DB06817|Raltegravir pol;UGT1A1 DB00961|Mepivacaine SCN10A common genes common pathways 36974:[DB06817 DB09054] DB06817|Raltegravir pol;UGT1A1 DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCG2;UGT1A1;ABCB1 GO:0017144| drug metabolic process CYP2B6;CYP3A4;UGT1A1;AOX1;CYP2C19;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP3A7;CYP3A5;CYP3A4;CYP2B6 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1;CYP3A4 36975:[DB06817 DB06825] DB06817|Raltegravir pol;UGT1A1 DB06825|Triptorelin GNRHR common genes common pathways 36976:[DB06817 DB01941] DB06817|Raltegravir pol;UGT1A1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways 36977:[DB06817 DB01565] DB06817|Raltegravir pol;UGT1A1 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 36978:[DB06817 DB14575] DB06817|Raltegravir pol;UGT1A1 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes UGT1A1 common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0031100| organ regeneration UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1 GO:0010033| response to organic substance UGT1A1 GO:0052696| flavonoid glucuronidation UGT1A1 GO:1904224| UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1 GO:0042594| response to starvation UGT1A1 GO:0007586| digestion UGT1A1 GO:0042493| response to drug UGT1A1 GO:0008210| estrogen metabolic process UGT1A1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0042573| retinoic acid metabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0001889| liver development UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1;CYP2C19 GO:0051552| flavone metabolic process UGT1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process UGT1A1 GO:0006789| bilirubin conjugation UGT1A1 GO:0052695| cellular glucuronidation UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 36979:[DB06817 DB12406] DB06817|Raltegravir pol;UGT1A1 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 36980:[DB06817 DB09199] DB06817|Raltegravir pol;UGT1A1 DB09199|Netoglitazone CYP3A4;CYP2C8 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1;CYP2C8 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP3A4 36981:[DB06817 DB05675] DB06817|Raltegravir pol;UGT1A1 DB05675|EP-2104R FGA common genes common pathways 36982:[DB06817 DB08439] DB06817|Raltegravir pol;UGT1A1 DB08439|Parecoxib PTGS2;LTF;CYP3A4;CYP2C9 common genes common pathways GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0008202| steroid metabolic process CYP2C9;CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2C9 GO:0042493| response to drug UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 36983:[DB06817 DB06494] DB06817|Raltegravir pol;UGT1A1 DB06494|Sufugolix GNRHR common genes common pathways 36984:[DB06817 DB07108] DB06817|Raltegravir pol;UGT1A1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways 36985:[DB06817 DB05239] DB06817|Raltegravir pol;UGT1A1 DB05239|Cobimetinib MAP2K1;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;ABCG2 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 36986:[DB06817 DB06264] DB06817|Raltegravir pol;UGT1A1 DB06264|Tolperisone CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 36987:[DB06817 DB13835] DB06817|Raltegravir pol;UGT1A1 DB13835|Caroverine CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 36988:[DB06817 DB01227] DB06817|Raltegravir pol;UGT1A1 DB01227|Levacetylmethadol OPRM1;CHRNB4;CHRNA3;CYP3A5;CYP3A7;CYP3A4;CYP19A1 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A7;CYP3A5;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:0045471| response to ethanol OPRM1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 36989:[DB06817 DB01699] DB06817|Raltegravir pol;UGT1A1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0045471| response to ethanol UGT1A1;ABAT GO:0042493| response to drug UGT1A1;ABAT 36990:[DB06817 DB11362] DB06817|Raltegravir pol;UGT1A1 DB11362|Selexipag PTGIR;CES1;CYP2C8;CYP3A4;SLCO1B1;SLCO1B3;ABCB1 common genes common pathways GO:0008152| metabolic process UGT1A1;CES1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C8;UGT1A1 GO:0032496| response to lipopolysaccharide PTGIR;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1 36991:[DB06817 DB06263] DB06817|Raltegravir pol;UGT1A1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0017144| drug metabolic process CBR1;UGT1A1 GO:0042493| response to drug UGT1A1;POR GO:0007584| response to nutrient POR;UGT1A1 36992:[DB06817 DB05710] DB06817|Raltegravir pol;UGT1A1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways 36993:[DB06817 DB06809] DB06817|Raltegravir pol;UGT1A1 DB06809|Plerixafor CXCR4 common genes common pathways 36994:[DB06817 DB09068] DB06817|Raltegravir pol;UGT1A1 DB09068|Vortioxetine SLC6A4;HTR3A;HTR7;HTR1B;HTR1A;ADRB1;CYP2D6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2A6;CYP2C8;CYP2B6 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP2D6;CYP3A4 GO:0045471| response to ethanol HTR1B;UGT1A1;HTR3A GO:0007584| response to nutrient UGT1A1;SLC6A4 GO:0042493| response to drug SLC6A4;HTR1B;UGT1A1 GO:0010033| response to organic substance UGT1A1;SLC6A4 GO:0017144| drug metabolic process CYP2C19;CYP2C8;UGT1A1;CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP2B6 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2D6;CYP2B6;CYP2C9;CYP2C19;CYP2C8;UGT1A1;CYP3A5 36995:[DB06817 DB01140] DB06817|Raltegravir pol;UGT1A1 DB01140|Cefadroxil SLC15A1;SLC22A5;SLC22A6;SLC15A2;SLC22A8 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 36996:[DB06817 DB12161] DB06817|Raltegravir pol;UGT1A1 DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;CYP3A4;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;CYP2D6;UGT1A1;CYP3A5 GO:0017144| drug metabolic process CYP3A4;CYP1A2;CYP2D6;CBR1;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 36997:[DB06817 DB05432] DB06817|Raltegravir pol;UGT1A1 DB05432|DAS-431 IV CALY common genes common pathways 36998:[DB06817 DB08909] DB06817|Raltegravir pol;UGT1A1 DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 36999:[DB06817 DB13125] DB06817|Raltegravir pol;UGT1A1 DB13125|Lusutrombopag MPL;CYP4A11;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;UGT1A1 37000:[DB06817 DB04901] DB06817|Raltegravir pol;UGT1A1 DB04901|Galiximab CD80 common genes common pathways 37001:[DB06817 DB06393] DB06817|Raltegravir pol;UGT1A1 DB06393|Xaliproden HTR1A common genes common pathways 37002:[DB06817 DB00747] DB06817|Raltegravir pol;UGT1A1 DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0007586| digestion UGT1A1;CHRM3 GO:0042493| response to drug UGT1A1;ABCB1 GO:0008152| metabolic process SI;UGT1A1 GO:0045471| response to ethanol CHRNB2;UGT1A1 37003:[DB06817 DB04855] DB06817|Raltegravir pol;UGT1A1 DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4;CYP2D6 GO:0042493| response to drug UGT1A1;ADRA1A;ABCB1 GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0046483| heterocycle metabolic process CYP2D6;CYP3A4;UGT1A1 37004:[DB06817 DB13909] DB06817|Raltegravir pol;UGT1A1 DB13909|Bismuth subgallate ALB common genes common pathways 37005:[DB06817 DB04065] DB06817|Raltegravir pol;UGT1A1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0017144| drug metabolic process ADH1A;UGT1A1 37006:[DB06817 DB00844] DB06817|Raltegravir pol;UGT1A1 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0045471| response to ethanol OPRK1;OPRM1;UGT1A1 GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 37007:[DB06817 DB01112] DB06817|Raltegravir pol;UGT1A1 DB01112|Cefuroxime SLC15A1;SLC15A2 common genes common pathways GO:0007586| digestion SLC15A1;UGT1A1 37008:[DB06817 DB11386] DB06817|Raltegravir pol;UGT1A1 DB11386|Chlorobutanol KCNH2 common genes common pathways 37009:[DB06817 DB13951] DB06817|Raltegravir pol;UGT1A1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0008210| estrogen metabolic process HSD17B1;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0008202| steroid metabolic process CYP17A1;UGT1A1;CYP11A1 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 37010:[DB06817 DB14003] DB06817|Raltegravir pol;UGT1A1 DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP4F2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;APOBR;LDLR;VLDLR;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1 GO:0007584| response to nutrient UGT1A1;TTPA GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 37011:[DB06817 DB09128] DB06817|Raltegravir pol;UGT1A1 DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug UGT1A1;HTR2A;DRD2 GO:0008202| steroid metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0017144| drug metabolic process CYP2D6;CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP2D6;CYP3A4 GO:0045471| response to ethanol UGT1A1;DRD2 37012:[DB06817 DB09202] DB06817|Raltegravir pol;UGT1A1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0032870| cellular response to hormone stimulus UGT1A1;ADRA2A GO:0042493| response to drug ADRA1A;UGT1A1 37013:[DB06817 DB11642] DB06817|Raltegravir pol;UGT1A1 DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4;CYP1A2;CYP2D6 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP1A2;CYP2D6;CYP2B6 GO:0017144| drug metabolic process CYP1A2;CYP2D6;CYP2B6;CYP3A4;UGT1A1 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1 37014:[DB06817 DB07177] DB06817|Raltegravir pol;UGT1A1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways 37015:[DB06817 DB03793] DB06817|Raltegravir pol;UGT1A1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0007586| digestion UGT1A1;SLC15A1 37016:[DB06817 DB02925] DB06817|Raltegravir pol;UGT1A1 DB02925|Piretanide SLC12A1 common genes common pathways 37017:[DB06817 DB06273] DB06817|Raltegravir pol;UGT1A1 DB06273|Tocilizumab IL6R;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0006953| acute-phase response UGT1A1;IL6R 37018:[DB06817 DB13501] DB06817|Raltegravir pol;UGT1A1 DB13501|Bendazac PTGS1;PTGS2 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 37019:[DB06817 DB00603] DB06817|Raltegravir pol;UGT1A1 DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways GO:0017144| drug metabolic process CYP2C8;UGT1A1;CYP3A4;CYP2C9 GO:0071392| cellular response to estradiol stimulus UGT1A1;ESR1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP2C9;CYP3A4 GO:0008152| metabolic process UGT1A1;HSD3B2 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 37020:[DB06817 DB01616] DB06817|Raltegravir pol;UGT1A1 DB01616|Alverine HTR1A common genes common pathways 37021:[DB06817 DB01250] DB06817|Raltegravir pol;UGT1A1 DB01250|Olsalazine TPMT;IFNG common genes common pathways 37022:[DB06817 DB09117] DB06817|Raltegravir pol;UGT1A1 DB09117|Paraldehyde ALDH2 common genes common pathways GO:0008152| metabolic process UGT1A1;ALDH2 37023:[DB06817 DB00170] DB06817|Raltegravir pol;UGT1A1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0007584| response to nutrient UGT1A1;NQO1 GO:0014070| response to organic cyclic compound CYP1A1;UGT1A1;CYP1A2;NQO1;F7 GO:0008152| metabolic process UGT1A1;MTHFR GO:0046483| heterocycle metabolic process UGT1A1;CYP1A1;CYP2E1;CYP1A2 GO:0045471| response to ethanol CYP2E1;UGT1A1;NQO1 GO:0001889| liver development PROC;UGT1A1;CYP1A1 GO:0043086| negative regulation of catalytic activity UGT1A1;NQO1 GO:0031100| organ regeneration F7;UGT1A1 GO:0017144| drug metabolic process AOX1;UGT1A1;CYP2E1;CYP1A1;CYP2A6;VKORC1;CYP1A2 GO:0008202| steroid metabolic process CYP2A6;CYP1A2;UGT1A1;CYP1A1;CYP2E1 GO:0010033| response to organic substance CYP1A2;CYP1A1;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A1;CYP1A2 GO:0006953| acute-phase response UGT1A1;F2 GO:0042493| response to drug CYP2E1;CYP1A1;UGT1A1;CYP1A2;MTHFR 37024:[DB06817 DB06403] DB06817|Raltegravir pol;UGT1A1 DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCB1;UGT1A1 GO:1904224| UGT1A9;UGT1A3;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;EDNRB GO:0052696| flavonoid glucuronidation UGT1A3;UGT1A9;UGT1A1 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A3;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A3;UGT1A9;UGT1A1 GO:0017144| drug metabolic process UGT1A9;UGT1A3;CYP3A4;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP3A5;UGT2B7;UGT1A1;CYP2C19 GO:0052695| cellular glucuronidation UGT2B7;UGT1A1;UGT1A9;UGT1A3 GO:2001030| negative regulation of cellular glucuronidation UGT1A1;UGT1A9;UGT1A3 GO:0008152| metabolic process UGT1A3;UGT1A9;UGT2B7;UGT1A1 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9;UGT1A3 GO:0014070| response to organic cyclic compound EDNRB;UGT1A1 37025:[DB06817 DB08577] DB06817|Raltegravir pol;UGT1A1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways 37026:[DB06817 DB01333] DB06817|Raltegravir pol;UGT1A1 DB01333|Cefradine mrcA;CYP3A4;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0007586| digestion UGT1A1;SLC15A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 37027:[DB06817 DB01339] DB06817|Raltegravir pol;UGT1A1 DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCB1 37028:[DB06817 DB13857] DB06817|Raltegravir pol;UGT1A1 DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 37029:[DB06817 DB05939] DB06817|Raltegravir pol;UGT1A1 DB05939|MK-0354 GPER1 common genes common pathways GO:0071392| cellular response to estradiol stimulus UGT1A1;GPER1 37030:[DB06817 DB06168] DB06817|Raltegravir pol;UGT1A1 DB06168|Canakinumab IL1B common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;IL1B 37031:[DB06817 DB00272] DB06817|Raltegravir pol;UGT1A1 DB00272|Betazole HRH2 common genes common pathways 37032:[DB06817 DB00952] DB06817|Raltegravir pol;UGT1A1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0045471| response to ethanol UGT1A1;HTR1B GO:0042493| response to drug HTR1B;UGT1A1 37033:[DB06817 DB11328] DB06817|Raltegravir pol;UGT1A1 DB11328|Tetradecyl hydrogen sulfate (ester) PROCR common genes common pathways 37034:[DB06817 DB00721] DB06817|Raltegravir pol;UGT1A1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0042493| response to drug BCHE;MAOB;SLC6A3;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;MAOB GO:0048545| response to steroid hormone stimulus UGT1A1;MAOB GO:0045471| response to ethanol SLC6A3;HTR3A;MAOB;GRIN3A;UGT1A1 GO:0071361| cellular response to ethanol UGT1A1;KCNMB1 GO:0014070| response to organic cyclic compound UGT1A1;SLC6A3 GO:0007584| response to nutrient UGT1A1;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;UGT1A1 37035:[DB06817 DB14507] DB06817|Raltegravir pol;UGT1A1 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways 37036:[DB06817 DB11071] DB06817|Raltegravir pol;UGT1A1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 37037:[DB06817 DB05232] DB06817|Raltegravir pol;UGT1A1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways 37038:[DB06817 DB00056] DB06817|Raltegravir pol;UGT1A1 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways 37039:[DB06817 DB08478] DB06817|Raltegravir pol;UGT1A1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0042493| response to drug TYMS;UGT1A1 GO:0045471| response to ethanol TYMS;UGT1A1 GO:0014070| response to organic cyclic compound TYMS;UGT1A1 GO:0051384| response to glucocorticoid stimulus UGT1A1;TYMS 37040:[DB06817 DB07931] DB06817|Raltegravir pol;UGT1A1 DB07931|Hexestrol AKR1C1;ESR1;NR1I2;NR1I3 common genes common pathways GO:0007586| digestion AKR1C1;UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0008202| steroid metabolic process NR1I2;UGT1A1 37041:[DB06817 DB08970] DB06817|Raltegravir pol;UGT1A1 DB08970|Fluprednidene CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process CYP3A4;UGT1A1 37042:[DB06817 DB06637] DB06817|Raltegravir pol;UGT1A1 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0014070| response to organic cyclic compound KCNC2;UGT1A1 GO:0045471| response to ethanol UGT1A1;KCNC2;CYP2E1 GO:0046483| heterocycle metabolic process CYP2E1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2E1 GO:0017144| drug metabolic process CYP2E1;UGT1A1 GO:0010033| response to organic substance KCNA5;UGT1A1 GO:0042493| response to drug CYP2E1;UGT1A1 37043:[DB06817 DB01746] DB06817|Raltegravir pol;UGT1A1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways 37044:[DB06817 DB06207] DB06817|Raltegravir pol;UGT1A1 DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0014070| response to organic cyclic compound ABCB4;UGT1A1 GO:0052695| cellular glucuronidation UGT2B7;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 GO:0008152| metabolic process UGT2B7;UGT1A1 GO:0010033| response to organic substance UGT1A1;ABCB4 GO:0008202| steroid metabolic process UGT1A1;UGT2B7;CYP3A4 GO:0071392| cellular response to estradiol stimulus ABCB4;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0042493| response to drug ABCB1;UGT1A1;ADRA1A;ABCB4 GO:0032496| response to lipopolysaccharide UGT1A1;ABCB4 37045:[DB06817 DB01406] DB06817|Raltegravir pol;UGT1A1 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 37046:[DB06817 DB00672] DB06817|Raltegravir pol;UGT1A1 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0017144| drug metabolic process CYP2C9;CYP2C19;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C9 GO:0042493| response to drug ABCC8;UGT1A1 GO:0007586| digestion UGT1A1;SLC15A1 GO:0032496| response to lipopolysaccharide UGT1A1;ABCC8 GO:0046483| heterocycle metabolic process CYP2C19;UGT1A1 37047:[DB06817 DB11079] DB06817|Raltegravir pol;UGT1A1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 37048:[DB06817 DB02300] DB06817|Raltegravir pol;UGT1A1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0032496| response to lipopolysaccharide UGT1A1;MPO 37049:[DB06817 DB08437] DB06817|Raltegravir pol;UGT1A1 DB08437|Puromycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;aat common genes common pathways GO:0045471| response to ethanol RPL15;UGT1A1 37050:[DB06817 DB12747] DB06817|Raltegravir pol;UGT1A1 DB12747|Tertomotide TERT common genes common pathways 37051:[DB06817 DB13170] DB06817|Raltegravir pol;UGT1A1 DB13170|Plecanatide GUCY1A2 common genes common pathways 37052:[DB06817 DB00092] DB06817|Raltegravir pol;UGT1A1 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways 37053:[DB06817 DB13983] DB06817|Raltegravir pol;UGT1A1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug UGT1A1;GABRG3 37054:[DB06817 DB11750] DB06817|Raltegravir pol;UGT1A1 DB11750|Clobetasol CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process UGT1A1;CYP3A4 37055:[DB06817 DB00484] DB06817|Raltegravir pol;UGT1A1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0017144| drug metabolic process AOX1;UGT1A1 GO:0032870| cellular response to hormone stimulus ADRA2A;UGT1A1 37056:[DB06817 DB05207] DB06817|Raltegravir pol;UGT1A1 DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0010033| response to organic substance TNF;UGT1A1 GO:0051384| response to glucocorticoid stimulus TNF;UGT1A1 37057:[DB06817 DB01188] DB06817|Raltegravir pol;UGT1A1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0042493| response to drug UGT1A1;ATP1A1 37058:[DB06817 DB11737] DB06817|Raltegravir pol;UGT1A1 DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0046483| heterocycle metabolic process CYP1A2;CYP3A4;UGT1A1 GO:0001889| liver development UGT1A1;EGFR GO:0014070| response to organic cyclic compound CYP1A2;EGFR;UGT1A1 GO:0042493| response to drug CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance UGT1A1;CYP1A2 GO:0017144| drug metabolic process UGT1A1;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP1A2;CYP3A4;CYP3A5;UGT1A1 GO:0071392| cellular response to estradiol stimulus EGFR;UGT1A1 37059:[DB06817 DB06548] DB06817|Raltegravir pol;UGT1A1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0008202| steroid metabolic process FDPS;UGT1A1 37060:[DB06817 DB11098] DB06817|Raltegravir pol;UGT1A1 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways 37061:[DB06817 DB00316] DB06817|Raltegravir pol;UGT1A1 DB00316|Acetaminophen PTGS2;PTGS1;FAAH;TRPV1;GSTP1;CYP2E1;CYP1A2;CYP3A4;CYP2D6;CYP1A1;CYP2A6;CYP2C8;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9;SLC22A6;ABCB1 common genes UGT1A1 common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;UGT1A1;CYP1A1 GO:0042573| retinoic acid metabolic process UGT1A9;UGT1A1 GO:0007584| response to nutrient UGT1A1 GO:0045939| negative regulation of steroid metabolic process UGT1A1 GO:0042167| heme catabolic process UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0032870| cellular response to hormone stimulus UGT1A1 GO:0052695| cellular glucuronidation UGT1A9;UGT1A1;UGT2B15;UGT1A6;UGT1A10 GO:0006789| bilirubin conjugation UGT1A1 GO:0043086| negative regulation of catalytic activity UGT1A1 GO:2001030| negative regulation of cellular glucuronidation UGT1A6;UGT1A1;UGT1A10;UGT1A9 GO:0001889| liver development CYP1A1;UGT1A1 GO:0070980| biphenyl catabolic process UGT1A1 GO:0045471| response to ethanol UGT1A1;CYP2E1;GSTP1 GO:0051552| flavone metabolic process UGT1A10;UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process CYP3A4;CYP1A2;CYP2D6;UGT1A1;CYP2E1;CYP1A1 GO:0071361| cellular response to ethanol UGT1A1 GO:0008152| metabolic process NAT2;UGT1A9;GSTP1;UGT1A10;UGT2B15;UGT1A1;UGT1A6 GO:0052697| xenobiotic glucuronidation UGT1A9;UGT1A10;UGT1A6;UGT1A1 GO:0045922| negative regulation of fatty acid metabolic process UGT1A9;UGT1A1;UGT1A6;UGT1A10 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A6;UGT1A1;UGT1A10 GO:0010033| response to organic substance UGT1A1;PTGS2;CYP1A1;CYP1A2 GO:0071392| cellular response to estradiol stimulus UGT1A1 GO:0008202| steroid metabolic process SULT1A3;CYP2C8;SULT1A1;UGT1A1;UGT2B15;CYP2E1;CYP1A1;SULT2A1;CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C9;SULT1E1 GO:0071466| cellular response to xenobiotic stimulus UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1 GO:0017144| drug metabolic process UGT1A6;UGT1A1;CYP2C8;UGT1A10;CYP2E1;CYP1A1;CYP2A6;CYP3A4;UGT1A9;CYP1A2;CYP2C9;CYP2D6 GO:0031100| organ regeneration GSTP1;UGT1A1 GO:0042493| response to drug CYP1A2;ABCB1;CYP2E1;CYP1A1;PTGS2;UGT1A1 GO:0008210| estrogen metabolic process SULT1A1;UGT1A1;SULT1E1 GO:0006953| acute-phase response UGT1A1 GO:0071385| cellular response to glucocorticoid stimulus UGT1A1;GSTP1 GO:1904224| UGT1A10;UGT1A1;UGT1A6;UGT1A9 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;CYP1A1;CYP1A2 GO:0007586| digestion SULT2A1;UGT1A1 GO:0042594| response to starvation UGT1A1 37062:[DB06817 DB00905] DB06817|Raltegravir pol;UGT1A1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0007584| response to nutrient UGT1A1;AKR1C3 GO:0008202| steroid metabolic process UGT1A1;AKR1C3 GO:0032496| response to lipopolysaccharide PTGER1;UGT1A1;PTGFR 37063:[DB06817 DB01078] DB06817|Raltegravir pol;UGT1A1 DB01078|Deslanoside ATP1A1 common genes common pathways GO:0042493| response to drug ATP1A1;UGT1A1 37064:[DB06817 DB09139] DB06817|Raltegravir pol;UGT1A1 DB09139|Technetium Tc-99m oxidronate ALB common genes common pathways 37065:[DB06817 DB11945] DB06817|Raltegravir pol;UGT1A1 DB11945|Avelumab CD274 common genes common pathways 37066:[DB06817 DB01020] DB06817|Raltegravir pol;UGT1A1 DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP3A4 37067:[DB06817 DB01260] DB06817|Raltegravir pol;UGT1A1 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus NR3C1;UGT1A1 GO:0017144| drug metabolic process CYP3A4;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;UGT1A1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 37068:[DB06817 DB05624] DB06817|Raltegravir pol;UGT1A1 DB05624|Teverelix GNRHR common genes common pathways 37069:[DB06817 DB11770] DB06817|Raltegravir pol;UGT1A1 DB11770|Talinolol CYP2D6 common genes common pathways GO:0046483| heterocycle metabolic process CYP2D6;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;UGT1A1 37070:[DB06817 DB04711] DB06817|Raltegravir pol;UGT1A1 DB04711|Iodipamide ALB common genes common pathways 37071:[DB06817 DB01065] DB06817|Raltegravir pol;UGT1A1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0010033| response to organic substance CYP1A1;CALR;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP2C9;CYP1A2;CYP1B1;CYP1A1;UGT1A1;CYP2C19 GO:0071392| cellular response to estradiol stimulus ESR1;UGT1A1 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP1A1;CYP2C9;CYP1A2 GO:0042493| response to drug CYP1A2;CYP1A1;CALR;UGT1A1 GO:0008210| estrogen metabolic process UGT1A1;CYP1B1 GO:0032496| response to lipopolysaccharide CYP1A2;MPO;CYP1A1;IDO1;UGT1A1 GO:0014070| response to organic cyclic compound CYP1A2;CYP1A1;UGT1A1 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1;CYP2C19;CYP1A1 GO:0001889| liver development UGT1A1;CYP1A1 37072:[DB06817 DB04830] DB06817|Raltegravir pol;UGT1A1 DB04830|Buformin SLC22A1 common genes common pathways 37073:[DB06817 DB06681] DB06817|Raltegravir pol;UGT1A1 DB06681|Belatacept CD86;CD80 common genes common pathways 37074:[DB06817 DB01535] DB06817|Raltegravir pol;UGT1A1 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;UGT1A1 GO:0045471| response to ethanol UGT1A1;OPRK1;OPRM1 37075:[DB06817 DB06897] DB06817|Raltegravir pol;UGT1A1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways 37076:[DB06817 DB01208] DB06817|Raltegravir pol;UGT1A1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;ABCC2;UGT1A1 GO:0042493| response to drug CYP1A2;ABCC2;ABCB1;UGT1A1 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0048545| response to steroid hormone stimulus UGT1A1;ABCC2 GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0046483| heterocycle metabolic process UGT1A1;CYP1A2 GO:0032870| cellular response to hormone stimulus UGT1A1;ABCC2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1 37077:[DB06817 DB01283] DB06817|Raltegravir pol;UGT1A1 DB01283|Lumiracoxib PTGS2;PTGS1;CYP2C9;CYP2C19;UGT1A9;CYP1A2 common genes common pathways GO:2001030| negative regulation of cellular glucuronidation UGT1A9;UGT1A1 GO:0052695| cellular glucuronidation UGT1A9;UGT1A1 GO:0051552| flavone metabolic process UGT1A1;UGT1A9 GO:0046483| heterocycle metabolic process CYP1A2;CYP2C19;UGT1A1 GO:0008152| metabolic process UGT1A1;UGT1A9 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;CYP1A2 GO:0042573| retinoic acid metabolic process UGT1A1;UGT1A9 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;UGT1A1;PTGS2 GO:1904224| UGT1A1;UGT1A9 GO:0052697| xenobiotic glucuronidation UGT1A1;UGT1A9 GO:0045922| negative regulation of fatty acid metabolic process UGT1A1;UGT1A9 GO:0052696| flavonoid glucuronidation UGT1A9;UGT1A1 GO:0010033| response to organic substance UGT1A1;PTGS2;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;CYP2C9;UGT1A1;CYP2C19 GO:0017144| drug metabolic process UGT1A9;CYP2C9;CYP1A2;CYP2C19;UGT1A1 37078:[DB06817 DB01166] DB06817|Raltegravir pol;UGT1A1 DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;PDE3A;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;UGT1A1;CYP2C19;CYP2D6;CYP1A2;CYP3A4 GO:0017144| drug metabolic process CYP1A2;CYP2D6;CYP3A4;UGT1A1;CYP2C19 GO:0046483| heterocycle metabolic process CYP1A2;CYP2D6;CYP3A4;CYP2C19;UGT1A1 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 37079:[DB06817 DB05311] DB06817|Raltegravir pol;UGT1A1 DB05311|Ecallantide KLKB1 common genes common pathways 37080:[DB06817 DB00778] DB06817|Raltegravir pol;UGT1A1 DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2B6;UGT1A1 GO:0017144| drug metabolic process CYP3A4;CYP2B6;UGT1A1 GO:0042493| response to drug UGT1A1;ABCB1 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 37081:[DB06817 DB11475] DB06817|Raltegravir pol;UGT1A1 DB11475|Tylosin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP3A4 GO:0046483| heterocycle metabolic process CYP3A4;UGT1A1 37082:[DB06817 DB08933] DB06817|Raltegravir pol;UGT1A1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes common pathways GO:0046483| heterocycle metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0017144| drug metabolic process UGT1A1;CYP2C19;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C19;UGT1A1 37083:[DB06817 DB05465] DB06817|Raltegravir pol;UGT1A1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0071385| cellular response to glucocorticoid stimulus FLT3;UGT1A1 GO:0031100| organ regeneration FLT3;UGT1A1 37084:[DB06817 DB06160] DB06817|Raltegravir pol;UGT1A1 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0017144| drug metabolic process UGT1A1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;UGT1A1 GO:0010033| response to organic substance CYP1A2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;CYP1A2 GO:0042493| response to drug UGT1A1;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;CYP1A2 GO:0046483| heterocycle metabolic process CYP1A2;UGT1A1 37085:[DB06817 DB01949] DB06817|Raltegravir pol;UGT1A1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 37086:[DB00480 DB07543] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 37087:[DB00480 DB11730] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042127| regulation of cell proliferation CDK6;PTGS2;CDK4 GO:0008284| positive regulation of cell proliferation PTGS2;CDK4 GO:0045786| negative regulation of cell cycle PTGS2;CDK6 GO:0010033| response to organic substance PTGS2;CDK4 GO:0007275| multicellular organismal development TNFSF11;CDK4 GO:0043065| positive regulation of apoptotic process CDK4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDK6;CDH5 GO:0030154| cell differentiation TNFSF11;CDK6 37088:[DB00480 DB00504] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00504|Levallorphan OPRM1 common genes common pathways GO:0019233| sensory perception of pain OPRM1;PTGS2 GO:0009314| response to radiation PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 37089:[DB00480 DB03685] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03685|Uridine monophosphate UCKL1;thyA;GLT6D1;LSM6;upp;B4GALT1;ISG20;pyrF;upp common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;B4GALT1 GO:0008285| negative regulation of cell proliferation B4GALT1;CDH5;PTGS2 GO:0042127| regulation of cell proliferation B4GALT1;PTGS2 GO:0007155| cell adhesion B4GALT1;CDH5 GO:0051260| protein homooligomerization B4GALT1;TNFSF11 37090:[DB00480 DB07926] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07926|N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE MMP1 common genes common pathways 37091:[DB00480 DB07218] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07218|6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE MAPK8IP1;MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process MAPK8;PTGS2;MAPK8IP1 GO:0043065| positive regulation of apoptotic process MAPK8;PTGS2 GO:0071260| cellular response to mechanical stimulus MAPK8;PTGS2 37092:[DB00480 DB01179] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBA4A;TUBB GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 37093:[DB00480 DB05127] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05127|ANA971 TLR7 common genes common pathways GO:0006954| inflammatory response TLR7;PTGS2 GO:0006955| immune response TLR7;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR7 37094:[DB00480 DB03372] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03372|3-Mercapto-1-(1,3,4,9-Tetrahydro-B-Carbolin-2-Yl)-Propan-1-One IL2 common genes common pathways GO:0006955| immune response TNFSF11;IL2 GO:0010469| regulation of receptor activity TNFSF11;IL2 GO:0050728| negative regulation of inflammatory response IL2;CDH5 GO:0007155| cell adhesion CDH5;IL2 GO:0043066| negative regulation of apoptotic process PTGS2;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL2 GO:0008284| positive regulation of cell proliferation IL2;PTGS2 37095:[DB00480 DB02059] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02059|Adenosine-5-Diphosphoribose EEF2;GAPDH;SIRT5;SIRT3 common genes common pathways GO:0055114| oxidation-reduction process GAPDH;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;EEF2 GO:0007568| aging EEF2;SIRT3;PTGS2 GO:0032355| response to estradiol stimulus EEF2;PTGS2 37096:[DB00480 DB01594] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0006810| transport GABRR1;GABRB1;GABRD;GABRR2;GABRB2;GABRA3;GABRA5;GABRG2;ABCB1;GABRB3;GABRA1 GO:0042493| response to drug ABCB1;GABRG3;PTGS2 37097:[DB00480 DB00645] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00645|Dyclonine SCN10A common genes common pathways GO:0019233| sensory perception of pain SCN10A;PTGS2 GO:0055085| transmembrane transport ABCB1;SCN10A 37098:[DB00480 DB04863] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0007155| cell adhesion ITGB3;ITGA2B;CDH5 37099:[DB00480 DB01580] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0007568| aging PTGS2;ADRB3 GO:0055085| transmembrane transport ABCB1;SLC22A2 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1;ADRB3 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 37100:[DB00480 DB00725] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00725|Homatropine Methylbromide CHRM2;CHRM1;CHRM4;CHRM5;CHRM3 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 37101:[DB00480 DB00838] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00838|Clocortolone NR3C1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 37102:[DB00480 DB06935] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06935|2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport ABCB1;TTR 37103:[DB00480 DB02789] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0055085| transmembrane transport SLC10A6;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008285| negative regulation of cell proliferation CDH5;SULT2B1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;SULT2B1 37104:[DB00480 DB01833] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01833|L-2-Amino-4-(Guanidinooxy)Butyric Acid NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0001525| angiogenesis NOS3;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;NOS3;PTGS2 37105:[DB00480 DB08128] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08128|(1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine PNMT common genes common pathways 37106:[DB00480 DB03439] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03439|4,6-dideoxy-4-amino-alpha-D-glucose AMY1A;AMY2A;AMY2A common genes common pathways 37107:[DB00480 DB06981] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06981|(2S)-2-(1H-indol-3-yl)pentanoic acid SKP1 common genes common pathways GO:0016567| protein ubiquitination SKP1;CRBN GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;SKP1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;SKP1 37108:[DB00480 DB06803] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2C9 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP2C9 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 37109:[DB00480 DB06914] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06914|1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE HMOX1 common genes common pathways GO:0006979| response to oxidative stress HMOX1;PTGS2 GO:0051260| protein homooligomerization TNFSF11;HMOX1 GO:0034605| cellular response to heat HMOX1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;HMOX1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMOX1 GO:0055114| oxidation-reduction process HMOX1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;HMOX1;PTGS2 GO:0008217| regulation of blood pressure HMOX1;PTGS2 GO:0043065| positive regulation of apoptotic process HMOX1;PTGS2 GO:0001525| angiogenesis HMOX1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HMOX1 37110:[DB00480 DB03937] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03937|Erythose-4-Phosphate kdsA;GPI common genes common pathways GO:0010469| regulation of receptor activity GPI;TNFSF11 GO:0032355| response to estradiol stimulus GPI;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;PTGS2 GO:0001525| angiogenesis GPI;PTGS2 37111:[DB00480 DB00940] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00940|Methantheline CHRM1;HRH2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0006955| immune response HRH2;TNFSF11 GO:0007613| memory HRH2;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH2 37112:[DB00480 DB01837] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01837|O-acetyl-L-serine PTGS1 common genes common pathways GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 37113:[DB00480 DB05943] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05943|Resatorvid CSF2RB;IL2RG common genes common pathways GO:0032496| response to lipopolysaccharide CSF2RB;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;CSF2RB GO:0006955| immune response IL2RG;TNFSF11 37114:[DB00480 DB09422] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09422|Soybean oil PPARA common genes common pathways GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;TNFSF11 GO:0006629| lipid metabolic process PTGS2;PPARA 37115:[DB00480 DB03245] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03245|S-4-Nitrobutyryl-Coa GCDH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GCDH 37116:[DB00480 DB00816] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00816|Orciprenaline ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 37117:[DB00480 DB01983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01983|2(S)-Amino-6-Boronohexanoic Acid ARG1 common genes common pathways GO:0032496| response to lipopolysaccharide ARG1;PTGS2 GO:0042493| response to drug ABCB1;ARG1;PTGS2 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0007568| aging ARG1;PTGS2 37118:[DB00480 DB02548] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02548|D-glucitol 6-phosphate GPI common genes common pathways GO:0010469| regulation of receptor activity GPI;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;GPI GO:0001525| angiogenesis PTGS2;GPI GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPI 37119:[DB00480 DB04185] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04185|Norvaline OTC;GATM common genes common pathways GO:0042493| response to drug OTC;ABCB1;PTGS2 GO:0007275| multicellular organismal development GATM;TNFSF11 37120:[DB00480 DB08962] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08962|Glibornuride CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;PTGS2 37121:[DB00480 DB03903] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03903|Tmr ACTA1 common genes common pathways GO:0010226| response to lithium ion PTGS2;ACTA1 37122:[DB00480 DB01165] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;ABCC2;CYP1A2;PTGS2;ABCC1 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0032496| response to lipopolysaccharide CYP1A2;ABCC2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0055085| transmembrane transport ABCC1;SLC22A5;ABCB11;SLC22A6;SLC22A4;ABCC2;ABCB1 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006810| transport ABCB1;ABCC2;ABCB11;ABCC1 GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1;SLC22A5 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 37123:[DB00480 DB00671] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC15A2;SLC22A5 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 37124:[DB00480 DB06685] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06685|Laquinimod CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 37125:[DB00480 DB05801] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05801|GTI 2040 RRM2 common genes common pathways GO:0055114| oxidation-reduction process RRM2;PTGS2 37126:[DB00480 DB01959] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01959|3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B;PDE4D common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity TNFSF11;PDE4D 37127:[DB00480 DB01618] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0008284| positive regulation of cell proliferation CHRM1;HTR1A;PTGS2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0042493| response to drug DRD2;HTR2A;PTGS2;ABCB1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2 GO:0019233| sensory perception of pain PTGS2;HTR2A 37128:[DB00480 DB07546] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07546|[1-(6-{6-[(1-methylethyl)amino]-1H-indazol-1-yl}pyrazin-2-yl)-1H-pyrrol-3-yl]acetic acid CSNK2A2 common genes common pathways 37129:[DB00480 DB05111] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05111|Fontolizumab IFNG common genes common pathways GO:0008284| positive regulation of cell proliferation IFNG;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;IFNG GO:0010469| regulation of receptor activity IFNG;TNFSF11 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;IFNG GO:0006955| immune response TNFSF11;IFNG 37130:[DB00480 DB00617] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00617|Paramethadione CACNA1I;CYP2E1;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0006810| transport CACNA1I;ABCB1 GO:0055085| transmembrane transport ABCB1;CACNA1I GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2E1;PTGS2;CYP2C8 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 37131:[DB00480 DB03600] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03600|Capric acid fabB;FURIN;GLTP;lipB;PPARG;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0098869| ALB;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FURIN GO:0010033| response to organic substance PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG 37132:[DB00480 DB01029] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;JUN GO:0010033| response to organic substance JUN;PTGS2 GO:0007568| aging PTGS2;JUN GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;PTGS1;CYP3A4;CYP2C9 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug JUN;PTGS2;ABCB1 GO:0048661| positive regulation of smooth muscle cell proliferation JUN;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;JUN;AGTR1;PTGS1 GO:0007612| learning PTGS2;JUN GO:0032496| response to lipopolysaccharide PTGS2;JUN GO:0034097| response to cytokine stimulus JUN;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;JUN GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;JUN GO:0008284| positive regulation of cell proliferation PTGS2;JUN GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound JUN;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;JUN GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0019722| calcium-mediated signaling AGTR1;TNFSF11 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0001525| angiogenesis JUN;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;CYP3A4 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0043065| positive regulation of apoptotic process JUN;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0009314| response to radiation JUN;PTGS2 37133:[DB00480 DB01436] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0007275| multicellular organismal development TNFSF11;VDR GO:0055074| calcium ion homeostasis TNFSF11;CYP27B1 GO:0007566| embryo implantation RXRA;PTGS2 GO:0033280| response to vitamin D PTGS2;CYP27B1 GO:0008285| negative regulation of cell proliferation CYP27B1;PTGS2;VDR;CDH5 GO:0032496| response to lipopolysaccharide PTGS2;CYP27B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;RXRA;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP27B1 GO:0046697| decidualization VDR;CYP27B1;PTGS2 GO:0030282| bone mineralization CYP27B1;PTGS2 GO:0009887| organ morphogenesis VDR;TNFSF11 37134:[DB00480 DB00866] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0045453| bone resorption ADRB2;TNFSF11 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;ADRB3;PTGS2;ADRB1 GO:0007568| aging PTGS2;ADRB3 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 37135:[DB00480 DB09069] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09069|Trimetazidine ACAA1 common genes common pathways GO:0006631| fatty acid metabolic process ACAA1;PTGS2 GO:0006629| lipid metabolic process ACAA1;PTGS2 37136:[DB00480 DB08256] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08256|N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE EPHX2 common genes common pathways GO:0006954| inflammatory response EPHX2;PTGS2 GO:0006629| lipid metabolic process EPHX2;PTGS2 GO:0008217| regulation of blood pressure EPHX2;PTGS2 37137:[DB00480 DB02563] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02563|Hexanoyl-CoA ECHS1 common genes common pathways GO:0006631| fatty acid metabolic process PTGS2;ECHS1 GO:0006629| lipid metabolic process PTGS2;ECHS1 37138:[DB00480 DB06233] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0010942| positive regulation of cell death MTOR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;MTOR GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;MTOR GO:0071456| cellular response to hypoxia MTOR;PTGS2 GO:0045670| regulation of osteoclast differentiation MTOR;TNFSF11 37139:[DB00480 DB07830] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07830|(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion DPP4;CDH5 37140:[DB00480 DB00843] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0007155| cell adhesion CDH5;ACHE GO:0042493| response to drug PTGS2;HTR2A;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2D6;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 37141:[DB00480 DB11785] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11785|Anisodamine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 37142:[DB00480 DB12450] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12450|Propyl Gallate ESR1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 37143:[DB00480 DB07233] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07233|N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan ADAM17 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;ADAM17 GO:0008284| positive regulation of cell proliferation ADAM17;PTGS2 GO:0007155| cell adhesion CDH5;ADAM17 GO:0032496| response to lipopolysaccharide ADAM17;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;ADAM17 37144:[DB00480 DB08936] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08936|Chlorcyclizine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 37145:[DB00480 DB04608] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04608|9-HYDROXY-4-PHENYL-6H-PYRROLO[3,4-C]CARBAZOLE-1,3-DIONE WEE1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle WEE1;ABCB1 37146:[DB00480 DB09160] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 37147:[DB00480 DB12872] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways GO:0034612| response to tumor necrosis factor PTGS2;ADAMTS13 GO:0032355| response to estradiol stimulus PTGS2;COL1A1 GO:0055114| oxidation-reduction process PTGS2;F8 GO:0042493| response to drug COL1A1;ABCB1;PTGS2 GO:0071260| cellular response to mechanical stimulus COL1A1;PTGS2 GO:0001503| ossification TNFSF11;COL1A1 37148:[DB00480 DB09371] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09371|Norethynodrel ESR1;AR;SHBG;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11;ESR1 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1;AR GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0006810| transport ABCB1;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 37149:[DB00480 DB00135] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;TH GO:0006631| fatty acid metabolic process PTGS2;TH GO:0042493| response to drug ABCB1;TH;PTGS2 GO:0007612| learning TH;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;TH GO:0055085| transmembrane transport SLC16A2;SLC16A10;ABCB1 GO:0009887| organ morphogenesis TNFSF11;TH GO:0006810| transport SLC16A2;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;TH GO:0006979| response to oxidative stress TAT;PTGS2 GO:0014070| response to organic cyclic compound TAT;PTGS2;TH GO:0007613| memory PTGS2;TH GO:0051384| response to glucocorticoid stimulus TAT;PTGS2 37150:[DB00480 DB02340] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02340|N-Acetyl-Serine F13A1 common genes common pathways 37151:[DB00480 DB06477] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06477|Sumanirole DRD2;DRD3;DRD4 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0007612| learning PTGS2;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD3;DRD2 GO:0008284| positive regulation of cell proliferation PTGS2;DRD3 GO:0042493| response to drug PTGS2;DRD2;DRD3;ABCB1 37152:[DB00480 DB02483] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02483|Etheno-Nad LDHA;BST1 common genes common pathways GO:0008284| positive regulation of cell proliferation BST1;PTGS2 GO:0042493| response to drug LDHA;PTGS2;ABCB1 GO:0055114| oxidation-reduction process LDHA;PTGS2 GO:0050727| regulation of inflammatory response BST1;PTGS2 GO:0043065| positive regulation of apoptotic process LDHA;PTGS2 GO:0014070| response to organic cyclic compound LDHA;PTGS2 37153:[DB00480 DB07092] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07092|(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 37154:[DB00480 DB11641] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 GO:0055085| transmembrane transport ABCB5;ABCB1 GO:0006810| transport ABCB1 GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:1901529| ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0006855| drug transmembrane transport ABCB1;ABCB5 GO:0030154| cell differentiation ABCB5;TNFSF11 GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006954| inflammatory response PTGS2;ORM1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37155:[DB00480 DB00654] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0008284| positive regulation of cell proliferation PTGFR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGFR;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;PTGFR GO:0055085| transmembrane transport SLCO2B1;ABCB1;SLC22A1 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0032355| response to estradiol stimulus PTGFR;PTGS2 37156:[DB00480 DB07907] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07907|(2S)-2-HYDROXYOCTANOIC ACID HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;PTGS2 GO:0055114| oxidation-reduction process HAO1;PTGS2 37157:[DB00480 DB02848] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02848|{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol FBP1 common genes common pathways 37158:[DB00480 DB04363] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04363|Mesobiliverdin Iv Alpha BLVRB common genes common pathways GO:0055114| oxidation-reduction process BLVRB;PTGS2 37159:[DB00480 DB09269] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09269|Phenylacetic acid CES1 common genes common pathways 37160:[DB00480 DB07255] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07255|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3-MORPHOLIN-4-YLPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0007155| cell adhesion CDH5;EPHB4 GO:0001525| angiogenesis EPHB4;PTGS2 GO:0007275| multicellular organismal development EPHB4;TNFSF11 37161:[DB00480 DB01218] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;PTGS2;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCB1;KCNH2 37162:[DB00480 DB00263] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00263|Sulfisoxazole CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 37163:[DB00480 DB07458] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07458|3-(1H-indol-3-yl)-4-{1-[2-(1-methylpyrrolidin-2-yl)ethyl]-1H-indol-3-yl}-1H-pyrrole-2,5-dione PRKACA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle PRKACA;ABCB1 GO:0034605| cellular response to heat PTGS2;PRKACA 37164:[DB00480 DB02857] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02857|Guanosine PNP common genes common pathways GO:0006955| immune response TNFSF11;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0042493| response to drug ABCB1;PNP;PTGS2 37165:[DB00480 DB06267] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A5;CYP3A4 GO:0043406| positive regulation of MAP kinase activity TNFSF11;PDE5A GO:0006629| lipid metabolic process PTGS2;CYP3A4 37166:[DB00480 DB06660] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06660|Saredutant TACR2 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction TACR2;PTGS2 37167:[DB00480 DB07129] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07129|(2R)-1-(2,6-dimethylphenoxy)propan-2-amine PLAU common genes common pathways GO:0010469| regulation of receptor activity PLAU;TNFSF11 GO:0042127| regulation of cell proliferation PLAU;PTGS2 37168:[DB00480 DB09090] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0055085| transmembrane transport ABCB1;CACNA1S GO:0006629| lipid metabolic process PTGS2;CYP3A4 37169:[DB00480 DB12836] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes ABCB1 common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;PTGER4 GO:0006955| immune response PTGER4;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;PTGER4 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGER4;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0042493| response to drug PTGS2;ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0050728| negative regulation of inflammatory response PTGER4;CDH5 GO:0006810| transport ABCB1 GO:0098869| PTGS2;ALB GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 37170:[DB00480 DB06281] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06281|Torcetrapib CETP;CYP11B2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP11B2 GO:0006629| lipid metabolic process CYP11B2;PTGS2;CETP 37171:[DB00480 DB03064] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03064|3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline HAO1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HAO1 GO:0006979| response to oxidative stress HAO1;PTGS2 37172:[DB00480 DB00139] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0008285| negative regulation of cell proliferation P3H1;PTGS2;CDH5;P3H3;P3H2;ASPH GO:0006629| lipid metabolic process PTGS2;HSD17B6 GO:0006810| transport ABCB1;SLC13A2 GO:0055085| transmembrane transport SLC13A3;SLC22A8;SLC13A1;SLC13A2;ABCB1 GO:0042493| response to drug ABCB1;OXCT1;PTGS2 GO:0055114| oxidation-reduction process SDHB;ASPH;P3H3;P3H2;PLOD1;ALDH5A1;TMLHE;SDHA;P4HA2;P3H1;P4HA1;PLOD3;BBOX1;SDHC;HSD17B6;SDHD;PTGS2 37173:[DB00480 DB02110] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02110|Protoporphyrin Ix Containing Co PTGS1;CYCS common genes common pathways GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS2;CYCS;PTGS1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 37174:[DB00480 DB01854] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01854|5-Bromonicotinamide ART1 common genes common pathways 37175:[DB00480 DB06156] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0007613| memory PTGS2;SLC6A4 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0007568| aging PTGS2;SLC6A3 GO:0006810| transport ABCB1;SLC6A2 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;SLC6A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0042493| response to drug PTGS2;SLC6A2;SLC6A3;SLC6A4;ABCB1 37176:[DB00480 DB09016] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09016|Butriptyline SLC6A4;HRH1;HTR2A common genes common pathways GO:0042493| response to drug PTGS2;HTR2A;ABCB1;SLC6A4 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0007568| aging HTR2A;PTGS2 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0006954| inflammatory response HRH1;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2;HRH1;SLC6A4 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;HTR2A 37177:[DB00480 DB01430] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01430|Almitrine ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0042493| response to drug ATP1A1;PTGS2;ABCB1 37178:[DB00480 DB04234] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04234|N2-({[(4-Bromophenyl)Methyl]Oxy}Carbonyl)-N1-[(1s)-1-Formylpentyl]-L-Leucinamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 37179:[DB00480 DB06701] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A2;SLC6A3;SLC6A4;ABCB1 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0007568| aging PTGS2;SLC6A3 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A4;ABCB1;PTGS2;SLC6A2;SLC6A3 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 GO:0007613| memory PTGS2;SLC6A4 37180:[DB00480 DB13164] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13164|Olmutinib EGFR common genes common pathways GO:0008284| positive regulation of cell proliferation EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGFR GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0006979| response to oxidative stress EGFR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0098609| CDH5;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0001503| ossification EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0014070| response to organic cyclic compound EGFR;PTGS2 37181:[DB00480 DB01198] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0043065| positive regulation of apoptotic process TSPO;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C8;PTGS2;CYP2E1;PTGS1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug ABCB1;TSPO;PTGS2;CYP2E1 GO:0010042| response to manganese ion TSPO;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0006810| transport GABRA5;GABRA3;GABRA1;ABCB1 GO:0007568| aging PTGS2;TSPO GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 37182:[DB00480 DB09334] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09334|Seractide acetate MC2R common genes common pathways 37183:[DB00480 DB03752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03752|P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid PTGS1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS2;PTGS1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 37184:[DB00480 DB04017] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04017|Clorgiline MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 37185:[DB00480 DB08291] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08291|N-(3-AMINOPROPYL)-2-NITROBENZENAMINE KAT2B common genes common pathways GO:0008285| negative regulation of cell proliferation KAT2B;PTGS2;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter KAT2B;TNFSF11 37186:[DB00480 DB00854] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0006955| immune response TNFSF11;OPRK1;OPRD1 GO:0019233| sensory perception of pain OPRM1;OPRK1;OPRD1;PTGS2 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 37187:[DB00480 DB03150] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03150|2',3'-Dideoxythymidine-5'-Monophosphate DTYMK common genes common pathways 37188:[DB00480 DB04614] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04614|(R)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 37189:[DB00480 DB08005] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08005|4-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-N-ethylpiperidine-1-carboxamide MAPK10 common genes common pathways 37190:[DB00480 DB06848] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06848|1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanamine TPSAB1 common genes common pathways 37191:[DB00480 DB08695] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08695|3-(4-nitrophenyl)-1H-pyrazole HPGDS common genes common pathways GO:0006693| prostaglandin metabolic process HPGDS;PTGS2 GO:0006629| lipid metabolic process PTGS2;HPGDS GO:0019371| cyclooxygenase pathway PTGS2;HPGDS GO:0006633| fatty acid biosynthetic process HPGDS;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS GO:0006631| fatty acid metabolic process HPGDS;PTGS2 37192:[DB00480 DB14050] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0006954| inflammatory response PTGS2;TRPV1 GO:0019233| sensory perception of pain TRPA1;PTGS2;TRPV1 GO:0043065| positive regulation of apoptotic process PTGS2;TRPV1 GO:0006629| lipid metabolic process PTGS2;DAGLA;TRPV1 GO:0014070| response to organic cyclic compound PTGS2;TRPA1 GO:0042493| response to drug PTGS2;TRPA1;ABCB1 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2 GO:0055085| transmembrane transport TRPA1;ABCB1;TRPV2;TRPV1 GO:0010033| response to organic substance TRPA1;PTGS2 GO:0034605| cellular response to heat TRPV1;PTGS2 GO:0006810| transport ABCB1;TRPV2;TRPV1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TRPV1 37193:[DB00480 DB01245] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0019233| sensory perception of pain CHRNB2;CHRNA4;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0007613| memory PTGS2;CHRNB2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0042493| response to drug PTGS2;ABCB1;BCHE GO:0007612| learning BCHE;CHRNB2;PTGS2 GO:0007155| cell adhesion ACHE;CDH5 GO:0006979| response to oxidative stress PTGS2;CHRNA4 37194:[DB00480 DB07145] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07145|(2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE ADAM17 common genes common pathways GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;ADAM17 GO:0007155| cell adhesion CDH5;ADAM17 GO:0008284| positive regulation of cell proliferation ADAM17;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;ADAM17 GO:0042493| response to drug ADAM17;ABCB1;PTGS2 37195:[DB00480 DB05785] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0032355| response to estradiol stimulus RARA;PTGS2 GO:0007568| aging JUN;PTGS2 GO:1990830| TNFSF11;RARG GO:0010033| response to organic substance PTGS2;JUN GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;JUN GO:0043066| negative regulation of apoptotic process JUN;RARG;PTGS2;RARA;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARB;TNFSF11;RARA;RARG;JUN GO:0008284| positive regulation of cell proliferation PTGS2;RARA;JUN;RARG;RARB GO:0034097| response to cytokine stimulus JUN;RARA;PTGS2 GO:0007612| learning PTGS2;JUN GO:0042127| regulation of cell proliferation PTGS2;JUN GO:0032496| response to lipopolysaccharide PTGS2;JUN GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;JUN GO:0042493| response to drug ABCB1;PTGS2;JUN GO:0008285| negative regulation of cell proliferation RARA;PTGS2;RARG;JUN;RARB;CDH5 GO:0014070| response to organic cyclic compound JUN;PTGS2 GO:0043065| positive regulation of apoptotic process RARB;PTGS2;JUN;RARG GO:0009314| response to radiation JUN;PTGS2 GO:0001525| angiogenesis PTGS2;JUN 37196:[DB00480 DB02580] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02580|Pentaglyme PFN2;gpmA;purA common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PFN2;PTGS2 37197:[DB00480 DB08617] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08617|4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE YARS common genes common pathways 37198:[DB00480 DB00119] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0010226| response to lithium ion PKLR;PTGS2 GO:0006629| lipid metabolic process SLC16A1;PC;PTGS2 GO:0010033| response to organic substance PTGS2;PKM GO:0055085| transmembrane transport SLC16A3;SLC16A5;SLC16A8;SLCO2A1;SLC16A6;SLC16A1;SLC16A2;SLC16A7;SLC16A4;ABCB1;SLC16A10 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;AGXT2 GO:0007568| aging ABAT;PTGS2 GO:0006810| transport SLC16A2;ABCB1 GO:0042493| response to drug PTGS2;ABCB1;ABAT GO:0055114| oxidation-reduction process PDHB;PTGS2 37199:[DB00480 DB02623] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02623|Aminophosphonic Acid-Guanylate Ester CDC42 common genes common pathways GO:0030154| cell differentiation CDC42;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation CDC42;PTGS2 GO:0098609| CDC42;CDH5 GO:0016567| protein ubiquitination CRBN;CDC42 GO:0034332| adherens junction organization CDC42;CDH5 GO:0046330| positive regulation of JNK cascade TNFSF11;CDC42 37200:[DB00480 DB01805] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01805|Monoisopropylphosphorylserine PRSS2;PRSS1;ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 37201:[DB00480 DB02185] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02185|2,4-Dihydroxy-7-(Methyloxy)-2h-1,4-Benzoxazin-3(4h)-One LCTL common genes common pathways 37202:[DB00480 DB11201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes PTGS2 common pathways GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:1902219| PTGS2 GO:0007568| aging PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0042493| response to drug PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:1990776| PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 37203:[DB00480 DB00370] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11;ADRB2;DRD3 GO:0008284| positive regulation of cell proliferation ADRA2A;ADRA1D;DRD3;HTR2A;HTR2B;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0007612| learning PTGS2;DRD1;DRD3;DRD5 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0042493| response to drug HTR2C;CYP1A2;DRD3;ABCB1;SLC6A4;ADRA1A;DRD2;SLC6A3;HTR2A;DRD1;SLC6A2;HTR2B;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0055114| oxidation-reduction process CYP1A2;CYP2C9;CYP2D6;CYP3A4;PTGS2;CYP2C8 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0032355| response to estradiol stimulus CYP1A2;SLC6A4;PTGS2 GO:0006810| transport ABCB1;SLC6A2 GO:0007568| aging PTGS2;HTR2A;SLC6A3;ADRA1A GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;ADRA2A;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0010033| response to organic substance SLC6A4;CYP1A2;PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;SLC6A2 GO:0009314| response to radiation OPRK1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6;CYP2C9;CYP1A2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0019233| sensory perception of pain PTGS2;HTR2A;OPRK1 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0006954| inflammatory response PTGS2;HRH1 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0006955| immune response OPRK1;TNFSF11 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;HTR2A;ADRA1A;ADRA1D;ADRA2C;HRH1 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0007613| memory PTGS2;HTR2A;DRD1;SLC6A4;HRH1 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1B;PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;DRD2;CDH5 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;SLC6A3 37204:[DB00480 DB02418] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02418|(R,R)-2,3-Butanediol UBE2D2 common genes common pathways GO:0016567| protein ubiquitination CRBN;UBE2D2 37205:[DB00480 DB11626] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11626|Tasonermin TNFRSF1A;TNFRSF1B common genes common pathways GO:0006955| immune response TNFRSF1A;TNFSF11;TNFRSF1B GO:0006954| inflammatory response TNFRSF1A;PTGS2;TNFRSF1B GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;TNFRSF1B GO:0006693| prostaglandin metabolic process TNFRSF1A;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;TNFRSF1A GO:0007275| multicellular organismal development TNFRSF1B;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNFRSF1A GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNFRSF1B;TNFRSF1A GO:0007568| aging TNFRSF1B;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;TNFRSF1B;TNFRSF1A GO:0019221| cytokine-mediated signaling pathway TNFSF11;TNFRSF1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFRSF1A;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;TNFRSF1A;TNFRSF1B GO:0032496| response to lipopolysaccharide PTGS2;TNFRSF1A;TNFRSF1B 37206:[DB00480 DB04510] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04510|3-phospho-D-glyceric acid PGK1;PGAM2;TPI1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;TPI1 GO:0071456| cellular response to hypoxia PTGS2;PGK1 37207:[DB00480 DB00392] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug PTGS2;BCHE;ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE 37208:[DB00480 DB08632] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08632|1,3,5-BENZENETRICARBOXYLIC ACID HBA1;HBB common genes common pathways GO:0010942| positive regulation of cell death HBB;PTGS2;HBA1 GO:0008217| regulation of blood pressure PTGS2;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB GO:0098869| HBB;HBA1;PTGS2 37209:[DB00480 DB09559] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09559|Necitumumab EGFR common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;EGFR GO:0043066| negative regulation of apoptotic process EGFR;PTGS2 GO:0008284| positive regulation of cell proliferation EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR GO:0098609| EGFR;CDH5 GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0006979| response to oxidative stress EGFR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR GO:0007275| multicellular organismal development TNFSF11;EGFR GO:0042327| positive regulation of phosphorylation TNFSF11;EGFR GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification EGFR;TNFSF11 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0014070| response to organic cyclic compound EGFR;PTGS2 37210:[DB00480 DB00768] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0051384| response to glucocorticoid stimulus PTGS2;S100B GO:0007613| memory HRH1;S100B;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A12;TNFSF11 GO:0006954| inflammatory response S100A12;PTGS2;HRH1 GO:0043065| positive regulation of apoptotic process PTGS2;S100B GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;S100B;S100A13;S100A12 GO:0043406| positive regulation of MAP kinase activity TNFSF11;S100A12 GO:0071456| cellular response to hypoxia S100B;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0002548| monocyte chemotaxis S100A12;TNFSF11 GO:0008284| positive regulation of cell proliferation S100B;S100A13;PTGS2 37211:[DB00480 DB00483] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0007155| cell adhesion CDH5;ACHE GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 37212:[DB00480 DB07297] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07297|5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE LCK common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade LCK;TNFSF11 GO:0042493| response to drug ABCB1;LCK;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;LCK GO:0050870| positive regulation of T cell activation TNFSF11;LCK 37213:[DB00480 DB00802] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00802|Alfentanil OPRM1;CYP3A4;CYP3A7;CYP3A5;ORM1;ALB;ABCB1 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0009314| response to radiation PTGS2;OPRM1 GO:0019233| sensory perception of pain OPRM1;PTGS2 GO:0006954| inflammatory response PTGS2;ORM1 GO:0098869| ALB;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;CYP3A5;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 37214:[DB00480 DB03680] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03680|Tartronate ME2;ME3 common genes common pathways GO:0055114| oxidation-reduction process ME3;ME2;PTGS2 37215:[DB00480 DB00416] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways 37216:[DB00480 DB01914] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0055085| transmembrane transport SLC2A12;SLC2A8;SLC2A11;SLC2A5;SLC2A2;SLC2A3;SLC2A7;SLC2A9;SLC2A1;SLC2A6;SLC2A4;SLC2A10;ABCB1;SLC5A1;SLC5A2 GO:0071456| cellular response to hypoxia SLC2A4;PTGS2 GO:0006810| transport ABCB1;SLC5A2 GO:0009750| response to fructose stimulus PTGS2;SLC2A5 GO:0042908| xenobiotic transport ABCB1;SLC2A1 GO:0050873| brown fat cell differentiation PTGS2;SLC2A4 GO:0071260| cellular response to mechanical stimulus SLC2A1;PTGS2 37217:[DB00480 DB04005] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04005|Uridine 5'-triphosphate UCK2 common genes common pathways 37218:[DB00480 DB03376] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03376|'5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 37219:[DB00480 DB06506] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 37220:[DB00480 DB04917] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04917|Renzapride HTR3A;HTR4 common genes common pathways 37221:[DB00480 DB00149] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00149|L-Leucine LARS2;BCAT2;BCAT1;LCMT2;LCMT1;LARS;SLC16A10;SLC16A2 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle LCMT1;ABCB1 GO:0055085| transmembrane transport SLC16A2;SLC16A10;ABCB1 GO:1990830| BCAT2;TNFSF11 GO:0006810| transport ABCB1;SLC16A2 37222:[DB00480 DB08251] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08251|4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID CASP3 common genes common pathways GO:0014070| response to organic cyclic compound CASP3;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2 GO:0010033| response to organic substance CASP3;PTGS2 GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0042493| response to drug ABCB1;CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process CASP3;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0032496| response to lipopolysaccharide PTGS2;CASP3 37223:[DB00480 DB03575] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03575|Phencyclidine GRIN3A;SIGMAR1;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2B6 37224:[DB00480 DB01917] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01917|Putrescine ODC1;AMD1;potF;ADRB1;ADRB2;SLC22A4 common genes common pathways GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0008284| positive regulation of cell proliferation PTGS2;ODC1 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0055085| transmembrane transport SLC22A4;ABCB1 37225:[DB00480 DB03256] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03256|(6R)-Folinic acid glyA;FTCD common genes common pathways 37226:[DB00480 DB08486] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08486|Efaproxiral HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB GO:0098869| HBB;PTGS2;HBA1 GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB GO:0008217| regulation of blood pressure HBB;PTGS2 37227:[DB00480 DB08302] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08302|3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid PPARG common genes common pathways GO:0010033| response to organic substance PTGS2;PPARG GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG 37228:[DB00480 DB00943] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00943|Zalcitabine pol;DCK;ALB;SLC22A6;SLC22A7;SLC29A1;SLC29A2 common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SLC29A1 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0098869| ALB;PTGS2 GO:0055085| transmembrane transport SLC22A7;SLC22A6;ABCB1 37229:[DB00480 DB07842] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07842|(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG 37230:[DB00480 DB09273] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0008285| negative regulation of cell proliferation ADORA2A;PTGS2;CDH5 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;ADORA2A GO:0006954| inflammatory response ADORA2A;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0071260| cellular response to mechanical stimulus PDE2A;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;ADORA2A;CYP1A2;ABCB1 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0050728| negative regulation of inflammatory response ADORA2A;CDH5 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 37231:[DB00480 DB05308] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05308|ANX-510 TYMS common genes common pathways GO:0042493| response to drug TYMS;PTGS2;ABCB1 GO:0034097| response to cytokine stimulus PTGS2;TYMS GO:0007568| aging TYMS;PTGS2 GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 37232:[DB00480 DB04764] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04764|[4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE TPSB2 common genes common pathways 37233:[DB00480 DB08289] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08289|N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM-N-OXIDE IGKC common genes common pathways GO:0006955| immune response IGKC;TNFSF11 37234:[DB00480 DB00732] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00732|Atracurium besylate CHRNA2 common genes common pathways 37235:[DB00480 DB07302] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07302|(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid PPARG common genes common pathways GO:0010033| response to organic substance PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 37236:[DB00480 DB02166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02166|Propidium ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 37237:[DB00480 DB14597] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14597|Lanadelumab KLKB1 common genes common pathways GO:0006954| inflammatory response KLKB1;PTGS2 37238:[DB00480 DB07047] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07047|2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0010469| regulation of receptor activity TTR;TNFSF11 37239:[DB00480 DB09517] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09517|Sodium ferric gluconate complex FTL;HBA1;HBB common genes common pathways GO:0008217| regulation of blood pressure HBB;PTGS2 GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;PTGS2 GO:0098869| HBB;PTGS2;HBA1 37240:[DB00480 DB07144] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07144|5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 37241:[DB00480 DB06739] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide TBXA2R;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug TBXA2R;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2C8;PTGS1;CYP3A4;CYP2A6;CYP2C9;CYP2B6 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;CYP3A4 GO:0006954| inflammatory response PTGS1;PTGS2;TBXA2R GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0045907| positive regulation of vasoconstriction TBXA2R;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TBXA2R GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 37242:[DB00480 DB04396] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04396|Thiodigalactoside NCAN;LGALS1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;LGALS1 GO:0007155| cell adhesion NCAN;CDH5 GO:0042493| response to drug LGALS1;ABCB1;PTGS2 37243:[DB00480 DB07670] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2C18 37244:[DB00480 DB07643] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07643|5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 37245:[DB00480 DB01079] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01079|Tegaserod HTR4;HTR2B;HTR2C;HTR2A;CYP1A2;CYP2C8;CYP2D6;CYP2E1;SLC6A4 common genes common pathways GO:0007613| memory HTR2A;PTGS2;SLC6A4 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;PTGS2 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0007568| aging PTGS2;HTR2A GO:0032355| response to estradiol stimulus CYP1A2;SLC6A4;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0010033| response to organic substance PTGS2;CYP1A2;SLC6A4 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A;HTR2B GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2B;HTR2A GO:0055114| oxidation-reduction process CYP2D6;CYP1A2;CYP2C8;PTGS2;CYP2E1 GO:0042493| response to drug HTR2C;CYP1A2;ABCB1;SLC6A4;CYP2E1;HTR2A;HTR2B;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 37246:[DB00480 DB08915] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08915|Aleglitazar PPARA;PPARG;NCOA1 common genes common pathways GO:0010033| response to organic substance PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA1;TNFSF11;PPARG;PPARA GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;NCOA1;PPARG GO:0006629| lipid metabolic process PPARG;PPARA;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 37247:[DB00480 DB06247] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06247|CX516 GRIA1 common genes common pathways 37248:[DB00480 DB07740] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07740|(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid HMGCS1 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;HMGCS1 GO:0006629| lipid metabolic process HMGCS1;PTGS2 GO:0010033| response to organic substance HMGCS1;PTGS2 GO:0042493| response to drug ABCB1;HMGCS1;PTGS2 37249:[DB00480 DB02404] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02404|1-Deoxy-1-Thio-Heptaethylene Glycol ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 37250:[DB00480 DB04469] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04469|1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007568| aging PDE4D;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;PDE4D 37251:[DB00480 DB00595] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00595|Oxytetracycline rpsI;rpsD;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC22A11;SLC22A6;SLC22A8;SLC22A7 37252:[DB00480 DB06530] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06530|Resiquimod TLR7;TLR8 common genes common pathways GO:0006955| immune response TNFSF11;TLR7 GO:0006954| inflammatory response PTGS2;TLR7;TLR8 GO:0071260| cellular response to mechanical stimulus TLR8;TLR7;PTGS2 37253:[DB00480 DB06607] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06607|Catumaxomab EPCAM;FCGR2A;FCGR3A;FCGR3B;CD3E;FCGR1A common genes common pathways GO:0006955| immune response FCGR3A;FCGR3B;TNFSF11;FCGR1A GO:0050870| positive regulation of T cell activation TNFSF11;CD3E GO:0008284| positive regulation of cell proliferation EPCAM;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EPCAM;TNFSF11 GO:0098609| CDH5;EPCAM GO:0051260| protein homooligomerization TNFSF11;CD3E 37254:[DB00480 DB08687] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08687|FG-2216 EGLN1;HIF1A common genes common pathways GO:0001525| angiogenesis HIF1A;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production HIF1A;PTGS2 GO:0030154| cell differentiation HIF1A;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;EGLN1 GO:0016567| protein ubiquitination HIF1A;CRBN GO:0042127| regulation of cell proliferation PTGS2;HIF1A GO:0043066| negative regulation of apoptotic process HIF1A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGLN1;HIF1A;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;HIF1A 37255:[DB00480 DB00122] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00122|Choline PCYT1B;ACHE;PCYT1A;PLD2;BCHE;PLD1;PHOSPHO1;CHRNA7;CEPT1;CHKB;CHAT;CHKA;CHDH;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC44A1;SLC44A4;SLC44A2;SLC44A3;SLC5A7 common genes common pathways GO:0006855| drug transmembrane transport SLC22A3;ABCB1;SLC22A1;SLC22A2;SLC22A5 GO:0008285| negative regulation of cell proliferation CDH5;BCHE;PTGS2 GO:0007613| memory PTGS2;CHRNA7 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;SLC44A2 GO:0006629| lipid metabolic process PCYT1A;PLD1;PLD2;PTGS2;CHKA;CHKB;PCYT1B;CEPT1 GO:0055085| transmembrane transport SLC22A2;SLC5A7;SLC44A1;SLC22A5;SLC44A3;SLC22A3;ABCB1;SLC44A2;SLC22A1;SLC44A4;SLC22A4 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0055114| oxidation-reduction process PTGS2;CHDH GO:0042493| response to drug ABCB1;BCHE;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0007155| cell adhesion ACHE;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 37256:[DB00480 DB04801] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04801|cis-Vaccenic acid PPARD common genes common pathways GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;PPARD GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0050728| negative regulation of inflammatory response PPARD;CDH5 GO:0046697| decidualization PPARD;PTGS2 GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0010033| response to organic substance PPARD;PTGS2 GO:0006629| lipid metabolic process PPARD;PTGS2 GO:0007566| embryo implantation PPARD;PTGS2 GO:0030154| cell differentiation TNFSF11;PPARD 37257:[DB00480 DB05391] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05391|liposomal prostaglandin E1 GP1BA common genes common pathways GO:0007155| cell adhesion GP1BA;CDH5 GO:0019221| cytokine-mediated signaling pathway TNFSF11;GP1BA 37258:[DB00480 DB08192] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08192|2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE SRC common genes common pathways GO:1902533| TNFSF11;SRC GO:0098609| SRC;CDH5 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0034332| adherens junction organization CDH5;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0070542| response to fatty acid PTGS2;SRC GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 37259:[DB00480 DB09421] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09421|Protirelin TRHR common genes common pathways 37260:[DB00480 DB07652] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07652|1-[2-DEOXYRIBOFURANOSYL]-2,4-DIFLUORO-5-METHYL-BENZENE-5'MONOPHOSPHATE POLK;rnhA common genes common pathways GO:0034644| cellular response to UV PTGS2;POLK 37261:[DB00480 DB08561] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08561|BENZYL 6-BENZYL-5,7-DIOXO-6,7-DIHYDRO-5H-[1,3]THIAZOLO[3,2-C]PYRIMIDINE-2-CARBOXYLATE MMP13 common genes common pathways GO:0030282| bone mineralization MMP13;PTGS2 37262:[DB00480 DB00046] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00046|Insulin Lispro INSR;IGF1R common genes common pathways GO:0007613| memory PTGS2;INSR GO:0006955| immune response TNFSF11;IGF1R GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;PTGS2 GO:0009887| organ morphogenesis INSR;TNFSF11 GO:0007612| learning PTGS2;INSR GO:0008284| positive regulation of cell proliferation IGF1R;PTGS2;INSR GO:0043066| negative regulation of apoptotic process IGF1R;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 37263:[DB00480 DB07282] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07282|3-({[(1Z)-(2-methoxyphenyl)methylidene]amino}oxy)propanoic acid TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport TTR;ABCB1 37264:[DB00480 DB02427] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02427|2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 37265:[DB00480 DB06694] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D GO:0045907| positive regulation of vasoconstriction ADRA2C;ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA1D;ADRA2A GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0007568| aging PTGS2;ADRA1A GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A 37266:[DB00480 DB05289] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05289|Tarenflurbil IKBKG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKG;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKG;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity IKBKG;TNFSF11 GO:0006954| inflammatory response PTGS2;IKBKG GO:0006955| immune response TNFSF11;IKBKG 37267:[DB00480 DB00168] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00168|Aspartame TRPV1;TAS1R2;TAS1R3;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071318| cellular response to ATP TRPV1;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC22A8;SLC22A6;TRPV1;SLC22A11 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TRPV1 GO:0034605| cellular response to heat PTGS2;TRPV1 GO:0006810| transport TRPV1;ABCB1 GO:0006954| inflammatory response TRPV1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;TRPV1 GO:0006629| lipid metabolic process TRPV1;PTGS2 GO:0019233| sensory perception of pain TRPV1;PTGS2 37268:[DB00480 DB07873] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07873|Lauryl alcohol diphosphonic acid GGPS1 common genes common pathways 37269:[DB00480 DB12307] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12307|Foretinib HGF;KDR;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0010469| regulation of receptor activity HGF;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP3A5;CYP3A43;CYP3A4 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;HGF GO:0050728| negative regulation of inflammatory response CDH5;HGF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HGF GO:0008284| positive regulation of cell proliferation PTGS2;HGF;KDR GO:0043066| negative regulation of apoptotic process PTGS2;HGF;KDR GO:0030154| cell differentiation TNFSF11;KDR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process HGF;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0001525| angiogenesis KDR;PTGS2 GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37270:[DB00480 DB05262] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05262|Oxypurinol XDH common genes common pathways GO:0055114| oxidation-reduction process XDH;PTGS2 37271:[DB00480 DB12436] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12436|Vofopitant TACR1 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;TACR1 GO:0008217| regulation of blood pressure TACR1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TACR1 GO:0014070| response to organic cyclic compound TACR1;PTGS2 GO:0019233| sensory perception of pain TACR1;PTGS2 GO:0006954| inflammatory response TACR1;PTGS2 GO:0032355| response to estradiol stimulus TACR1;PTGS2 37272:[DB00480 DB06920] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06920|Eribaxaban F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 37273:[DB00480 DB06953] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06953|2-CHLORO-5-(3-CHLORO-PHENYL)-6-[(4-CYANO-PHENYL)-(3-METHYL-3H-IMIDAZOL-4-YL)- METHOXYMETHYL]-NICOTINONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FNTA GO:0042127| regulation of cell proliferation FNTB;PTGS2 37274:[DB00480 DB04105] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04105|N-Heptylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process ADH1B;PTGS2 37275:[DB00480 DB05407] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05407|TBC-3711 EDN1 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;EDN1 GO:0001516| prostaglandin biosynthetic process EDN1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;EDN1 GO:0008217| regulation of blood pressure PTGS2;EDN1 GO:0019233| sensory perception of pain EDN1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;EDN1 GO:0010469| regulation of receptor activity EDN1;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;EDN1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EDN1 GO:0043406| positive regulation of MAP kinase activity EDN1;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;EDN1 GO:0008284| positive regulation of cell proliferation PTGS2;EDN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EDN1 GO:0042493| response to drug EDN1;ABCB1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation EDN1;PTGS2 37276:[DB00480 DB12555] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12555|Nelotanserin HTR2A common genes common pathways GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging HTR2A;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;HTR2A GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0007613| memory PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A 37277:[DB00480 DB06469] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0030154| cell differentiation FLT3;TNFSF11 GO:0008284| positive regulation of cell proliferation FLT3;PTGS2 GO:0010243| response to organic nitrogen FLT3;PTGS2 GO:0019221| cytokine-mediated signaling pathway FLT3;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0043406| positive regulation of MAP kinase activity FLT3;TNFSF11 37278:[DB00480 DB06741] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06741|Gavestinel GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;UGT1A1;UGT1A3;UGT1A9;UGT2B4 common genes common pathways GO:0007612| learning PTGS2;GRIN1;GRIN2A GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;GRIN1 GO:0042493| response to drug ABCB1;GRIN2A;UGT1A1;PTGS2 GO:0006810| transport GRIN2A;GRIN2B;ABCB1;GRIN2C GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0019233| sensory perception of pain GRIN2A;PTGS2;GRIN1 GO:0043065| positive regulation of apoptotic process GRIN1;PTGS2;GRIN2A GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0007613| memory PTGS2;GRIN1;GRIN2A GO:0019722| calcium-mediated signaling GRIN2C;GRIN1;GRIN2A;GRIN2B;GRIN2D;TNFSF11 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 37279:[DB00480 DB08655] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08655|9-ACETYL-2,3,4,9-TETRAHYDRO-1H-CARBAZOL-1-ONE CREBBP common genes common pathways GO:0034644| cellular response to UV CREBBP;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREBBP;TNFSF11 37280:[DB00480 DB02360] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02360|Bis-Napthyl Beta-Ketophosphonic Acid CTSG common genes common pathways GO:0006955| immune response CTSG;TNFSF11 GO:0032496| response to lipopolysaccharide CTSG;PTGS2 37281:[DB00480 DB01866] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01866|RU79256 SRC common genes common pathways GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| CDH5;SRC GO:1902533| TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC 37282:[DB00480 DB07053] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07053|2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0010033| response to organic substance PTGS2;PPARG 37283:[DB00480 DB14583] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0038001| paracrine signaling TNFSF11;PGR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;NR3C1;PGR;TNFSF11 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006810| transport ABCB1;AR 37284:[DB00480 DB08867] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006954| inflammatory response ORM1;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0098869| ALB;PTGS2 GO:0006810| transport AR;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR;PGR;NR3C1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 37285:[DB00480 DB01251] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0007613| memory PTGS2;ABCC8 GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0055085| transmembrane transport ABCC8;ABCB1 GO:0032496| response to lipopolysaccharide ABCC8;PTGS2;KCNJ8 GO:0042493| response to drug ABCB1;PTGS2;ABCC8 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 37286:[DB00480 DB07265] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07265|3-(9-HYDROXY-1,3-DIOXO-4-PHENYL-2,3-DIHYDROPYRROLO[3,4-C]CARBAZOL-6(1H)-YL)PROPANOIC ACID WEE1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle WEE1;ABCB1 37287:[DB00480 DB07450] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07450|(R)-minalrestat AKR1B1 common genes common pathways GO:0010033| response to organic substance PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 37288:[DB00480 DB04942] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04942|Tamibarotene RARA;RARB;CRABP1 common genes common pathways GO:0034097| response to cytokine stimulus PTGS2;RARA GO:0043066| negative regulation of apoptotic process RARB;RARA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;RARB;TNFSF11 GO:0008284| positive regulation of cell proliferation RARB;RARA;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;RARA GO:0043065| positive regulation of apoptotic process RARB;PTGS2 GO:0007275| multicellular organismal development TNFSF11;CRABP1 GO:0008285| negative regulation of cell proliferation RARB;CDH5;PTGS2;RARA 37289:[DB00480 DB06943] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06943|(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol ADAM17 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;ADAM17 GO:0032496| response to lipopolysaccharide ADAM17;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;ADAM17 GO:0007155| cell adhesion ADAM17;CDH5 GO:0033209| tumor necrosis factor-mediated signaling pathway ADAM17;TNFSF11 37290:[DB00480 DB04725] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes PTGS2 common pathways GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0055114| oxidation-reduction process CYP2J2;CYP2C9;PTGS2;CYP2C8;ALOX5 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0007568| aging PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:1990776| PTGS2 GO:0006629| lipid metabolic process PTGS2;PLA2G2E;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0006954| inflammatory response ALOX5;PTGS2;PLA2G2E GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0008217| regulation of blood pressure PTGS2 37291:[DB00480 DB00153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP24A1;CYP2R1;PTGS2;CYP27B1;CYP27A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 GO:0032496| response to lipopolysaccharide CYP27B1;PTGS2 GO:0009887| organ morphogenesis TNFSF11;VDR GO:0030282| bone mineralization CYP27B1;PTGS2 GO:0046697| decidualization VDR;PTGS2;CYP27B1 GO:0055074| calcium ion homeostasis TNFSF11;CYP27B1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007275| multicellular organismal development TNFSF11;VDR GO:0008285| negative regulation of cell proliferation CDH5;CYP27B1;PTGS2;VDR GO:0033280| response to vitamin D CYP24A1;CYP27B1;PTGS2 37292:[DB00480 DB00735] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00735|Naftifine SQLE common genes common pathways GO:0055114| oxidation-reduction process SQLE;PTGS2 GO:0010033| response to organic substance PTGS2;SQLE 37293:[DB00480 DB02846] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02846|L-thioproline ANXA5 common genes common pathways GO:0010033| response to organic substance PTGS2;ANXA5 GO:0043066| negative regulation of apoptotic process ANXA5;PTGS2 37294:[DB00480 DB03673] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03673|Beta(2-Thienyl)Alanine PAH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;PAH 37295:[DB00480 DB04867] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04867|Lintitript CCKAR common genes common pathways 37296:[DB00480 DB00770] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;ABCC4 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2 GO:0055114| oxidation-reduction process ABCC4;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;ABCC4 GO:0042127| regulation of cell proliferation PTGER2;PTGS2 GO:0032496| response to lipopolysaccharide PTGER2;PTGER1;PTGS2 GO:0010033| response to organic substance ABCC4;PTGS2 GO:0055085| transmembrane transport ABCC5;ABCB1;ABCC4;SLCO2A1;SLCO3A1;SLCO2B1;SLC22A6 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006810| transport ABCC5;ABCB1 GO:0006955| immune response PTGDR2;TNFSF11 GO:0014070| response to organic cyclic compound ABCC4;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;PTGDR2 37297:[DB00480 DB05956] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RXRA GO:0006810| transport GRIN2B;ABCB1 GO:0019722| calcium-mediated signaling GRIN2B;TNFSF11 GO:0007566| embryo implantation RXRA;PTGS2 37298:[DB00480 DB07416] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07416|(2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE IGKC common genes common pathways GO:0006955| immune response IGKC;TNFSF11 37299:[DB00480 DB04967] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04967|Lucanthone TOP2A;APEX1;TOP1 common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0007568| aging APEX1;PTGS2 GO:0010243| response to organic nitrogen APEX1;PTGS2 GO:0055114| oxidation-reduction process APEX1;PTGS2 GO:0042493| response to drug ABCB1;APEX1;PTGS2;TOP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A 37300:[DB00480 DB07422] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07422|(2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0006810| transport ABCB1;AR 37301:[DB00480 DB07205] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07205|N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE YARS common genes common pathways 37302:[DB00480 DB09229] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2;ADRA1B;ADRA2C;ADRA1D GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0007275| multicellular organismal development ADRA1D;TNFSF11;ADRA1B GO:0006954| inflammatory response PTGS2;ORM1 GO:0098869| ALB;PTGS2 GO:0007568| aging PTGS2;ADRA1A GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0055085| transmembrane transport CACNA1F;ABCB1;CACNA1S;CACNA1C;CACNA1D GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A 37303:[DB00480 DB06094] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06094|Apatorsen HSPB1 common genes common pathways GO:0043066| negative regulation of apoptotic process HSPB1;PTGS2 37304:[DB00480 DB09078] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1B1;SLC22A8;ABCB11;SLC22A2;SLC22A6;ABCG2;ABCB1 GO:0009887| organ morphogenesis TNFSF11;FGFR2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0043406| positive regulation of MAP kinase activity FLT1;FGFR1;KIT;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006810| transport ABCB1;ABCB11;ABCG2 GO:0030282| bone mineralization PTGS2;FGFR2;FGFR3 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0042493| response to drug CYP1A2;ABCB1;ABCG2;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP2D6;PTGS2;AOX1;CYP2C8;CYP2C19 GO:0002548| monocyte chemotaxis FLT1;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation FGFR2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade KIT;FGFR1;FGFR2;FGFR4;TNFSF11;FGFR3 GO:0019221| cytokine-mediated signaling pathway TNFSF11;KIT GO:0042127| regulation of cell proliferation KIT;PTGS2;FGFR1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide FGFR2;CYP1A2;PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;FLT4 GO:0043066| negative regulation of apoptotic process KDR;FLT4;PTGS2 GO:0008284| positive regulation of cell proliferation FLT4;KDR;PTGS2;FGFR1;KIT;FLT1;FGFR4;FGFR2;FGFR3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;FGFR2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2;SLC22A2 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0030154| cell differentiation TNFSF11;KDR;FLT1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;KIT GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0006954| inflammatory response PTGS2;KIT GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4 GO:0007275| multicellular organismal development TNFSF11;KDR;FLT1 GO:0001525| angiogenesis FGFR2;KDR;FLT4;PTGS2;FGFR1;FLT1 GO:0009314| response to radiation KIT;PTGS2 GO:0006629| lipid metabolic process CYP1A2;CYP2D6;CYP2C9;CYP3A4;PTGS2 37305:[DB00480 DB05390] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05390|INS 316 P2RY2 common genes common pathways 37306:[DB00480 DB08484] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08484|4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE FBP1 common genes common pathways 37307:[DB00480 DB04974] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04974|AP1903 MTOR common genes common pathways GO:0010942| positive regulation of cell death MTOR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;MTOR GO:0071456| cellular response to hypoxia PTGS2;MTOR GO:0045670| regulation of osteoclast differentiation TNFSF11;MTOR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;MTOR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;MTOR 37308:[DB00480 DB02953] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02953|2-Thiomethyl-3-Phenylpropanoic Acid MMP8 common genes common pathways 37309:[DB00480 DB00417] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC15A1 GO:0006810| transport ABCB1;SLC15A1 37310:[DB00480 DB02234] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02234|S-Ethylisothiourea NOS2;NOS3 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;NOS3;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0055114| oxidation-reduction process PTGS2;NOS2;NOS3 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 37311:[DB00480 DB04471] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04471|2-Phenyl-1-[4-(2-Piperidin-1-Yl-Ethoxy)-Phenyl]-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 37312:[DB00480 DB08045] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08045|4-{4-[4-(3-AMINOPROPOXY)PHENYL]-1H-PYRAZOL-5-YL}-6-CHLOROBENZENE-1,3-DIOL HSP90AB1 common genes common pathways GO:0010033| response to organic substance PTGS2;HSP90AB1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AB1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;HSP90AB1 GO:0043066| negative regulation of apoptotic process HSP90AB1;PTGS2 37313:[DB00480 DB06885] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06885|3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0010469| regulation of receptor activity TTR;TNFSF11 37314:[DB00480 DB02263] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02263|Glyceraldehyde-3-Phosphate SLCO2A1 common genes common pathways GO:0055085| transmembrane transport SLCO2A1;ABCB1 37315:[DB00480 DB03072] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03072|2-{3-[4-(4-Fluorophenyl)-3,6-Dihydro-1(2h)-Pyridinyl]Propyl}-8-Methyl-4(3h)-Quinazolinone PARP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 37316:[DB00480 DB06311] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06311|Darapladib PLA2G4A common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLA2G4A GO:0006629| lipid metabolic process PTGS2;PLA2G4A 37317:[DB00480 DB02696] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02696|6-Aminohexyl-Uridine-C1,5'-Diphosphate B4GALT1 common genes common pathways GO:0043065| positive regulation of apoptotic process B4GALT1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;B4GALT1;PTGS2 GO:0007155| cell adhesion B4GALT1;CDH5 GO:0042127| regulation of cell proliferation PTGS2;B4GALT1 GO:0051260| protein homooligomerization B4GALT1;TNFSF11 37318:[DB00480 DB08121] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08121|(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0010033| response to organic substance PPARG;PTGS2 GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 37319:[DB00480 DB03192] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03192|3r-Hydroxydecanoyl-Coa HSD17B4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HSD17B4 GO:0006631| fatty acid metabolic process PTGS2;HSD17B4 GO:0006629| lipid metabolic process HSD17B4;PTGS2 37320:[DB00480 DB14515] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14515|Magnesium lactate ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0008217| regulation of blood pressure PTGS2;ATP1A1 GO:0042493| response to drug ATP1A1;PTGS2;ABCB1 37321:[DB00480 DB06985] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06985|2-[({4-[2-(trifluoromethyl)phenyl]piperidin-1-yl}carbonyl)amino]benzoic acid RBP4 common genes common pathways 37322:[DB00480 DB03405] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03405|N2-[(Benzyloxy)carbonyl]-N-[(3R)-1-{N-[(benzyloxy)carbonyl]-L-leucyl}-4-oxo-3-pyrrolidinyl]-L-leucinamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 37323:[DB00480 DB11157] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11157|Anthralin KRT2;MAPK8IP1;KRT12 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;MAPK8IP1 37324:[DB00480 DB08550] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08550|7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline PNMT common genes common pathways 37325:[DB00480 DB03267] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03267|1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0032496| response to lipopolysaccharide PCK1;PTGS2 GO:0007568| aging PTGS2;PCK1 GO:0071456| cellular response to hypoxia PCK1;PTGS2 GO:0006629| lipid metabolic process PTGS2;PCK1 37326:[DB00480 DB00536] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00536|Guanidine argG;GAMT;RNASE1;DLG4;ALDH2;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A8;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0055085| transmembrane transport SLC22A8;SLC22A5;SLC22A2;SLC47A1;SLC22A3;SLC47A2;SLC22A4;DLG4;ABCB1;SLC22A1 GO:0009887| organ morphogenesis GAMT;TNFSF11 GO:0007612| learning PTGS2;DLG4 GO:0055114| oxidation-reduction process PTGS2;ALDH2 GO:0006855| drug transmembrane transport ABCB1;SLC22A1;SLC47A2;SLC47A1;SLC22A3;SLC22A2;SLC22A5 37327:[DB00480 DB12569] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12569|Tonapofylline ADORA1 common genes common pathways GO:0050728| negative regulation of inflammatory response CDH5;ADORA1 GO:0043066| negative regulation of apoptotic process PTGS2;ADORA1 GO:0097756| ADORA1;PTGS2 GO:0006954| inflammatory response PTGS2;ADORA1 GO:0008285| negative regulation of cell proliferation CDH5;ADORA1;PTGS2 37328:[DB00480 DB03008] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03008|5-fluoro-beta-L-gulosyl fluoride MAN2A1 common genes common pathways 37329:[DB00480 DB00882] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes ABCB1 common pathways GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP11A1;CYP1A2;CYP19A1;PTGS2;CYP2E1;CYP1A1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;CYP1A1;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;CYP1A1;PTGS2 GO:1901529| ABCB1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0010033| response to organic substance CYP1A1;PTGS2;CYP1A2 GO:0007568| aging CYP1A1;PTGS2 GO:0006810| transport ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0006629| lipid metabolic process CYP11A1;CYP1A2;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;CYP1A1 GO:0042908| xenobiotic transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 37330:[DB00480 DB03841] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03841|Y-700 XDH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;XDH 37331:[DB00480 DB03882] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03882|5-Alpha-Androstane-3-Beta,17beta-Diol ESR2;SHBG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2 37332:[DB00480 DB07234] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07234|3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione MAPKAPK2 common genes common pathways GO:0006954| inflammatory response PTGS2;MAPKAPK2 GO:0032496| response to lipopolysaccharide PTGS2;MAPKAPK2 GO:0034097| response to cytokine stimulus PTGS2;MAPKAPK2 37333:[DB00480 DB05284] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05284|CA4P TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 37334:[DB00480 DB08498] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08498|(1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0010033| response to organic substance CASP3;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;PTGS2 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CASP3 GO:0042493| response to drug ABCB1;CASP3;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0014070| response to organic cyclic compound CASP3;PTGS2 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2 37335:[DB00480 DB01969] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01969|Trifluoroacetonyl Coenzyme A CS common genes common pathways 37336:[DB00480 DB00172] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways GO:0010942| positive regulation of cell death PRODH;PTGS2 GO:0008285| negative regulation of cell proliferation P3H2;P3H3;CDH5;PTGS2;P3H1 GO:0055114| oxidation-reduction process P4HA1;P3H1;PYCR1;PTGS2;P3H3;P3H2;PRODH;P4HA2;PYCR2 GO:0043066| negative regulation of apoptotic process PPIF;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC16A10;SLC6A14 GO:0006979| response to oxidative stress PTGS2;PPIF GO:0006810| transport SLC6A7;SLC6A14;ABCB1 37337:[DB00480 DB01989] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01989|Carbobenzoxy-Pro-Lys-Phe-Y(Po2)-Ala-Pro-Ome TLL2 common genes common pathways GO:0007275| multicellular organismal development TLL2;TNFSF11 GO:0030154| cell differentiation TLL2;TNFSF11 37338:[DB00480 DB07906] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07906|[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL PNMT common genes common pathways 37339:[DB00480 DB02419] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02419|Ethyl Oxo(Piperidin-1-Yl)Acetate PPIA common genes common pathways 37340:[DB00480 DB00497] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0006955| immune response TNFSF11;OPRK1;OPRD1 GO:0006954| inflammatory response PTGS2;ORM1 GO:0019233| sensory perception of pain PTGS2;OPRD1;OPRK1;OPRM1 GO:0009314| response to radiation PTGS2;OPRM1;OPRK1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2;CYP3A5 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 37341:[DB00480 DB12128] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12128|Ulimorelin GHSR common genes common pathways GO:0050728| negative regulation of inflammatory response GHSR;CDH5 GO:0032355| response to estradiol stimulus GHSR;PTGS2 GO:0046697| decidualization GHSR;PTGS2 37342:[DB00480 DB07405] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07405|1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0055114| oxidation-reduction process NOS2;PTGS2 37343:[DB00480 DB08746] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08746|1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 37344:[DB00480 DB00711] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00711|Diethylcarbamazine ALOX5;PTGS1;BCHE common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning BCHE;PTGS2 GO:0019372| lipoxygenase pathway ALOX5;PTGS2 GO:0055114| oxidation-reduction process PTGS2;ALOX5;PTGS1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 37345:[DB00480 DB07627] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07627|(2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CAPN1 37346:[DB00480 DB05420] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05420|Gallium maltolate RRM1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;RRM1 37347:[DB00480 DB08903] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 37348:[DB00480 DB08931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0007568| aging PTGS2;CYP1A1 GO:0006810| transport ABCG2;ABCB1 GO:0098869| PTGS2;ALB GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0042493| response to drug CYP1A1;PTGS2;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP2J2;CYP3A4;CYP1A1;PTGS2;CYP2C8 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006954| inflammatory response PTGS2;ORM1 37349:[DB00480 DB03187] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03187|6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid GCSH common genes common pathways 37350:[DB00480 DB01058] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP3A7;CYP3A5;CYP3A4;CYP3A43;CYP1A2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PTGS2 37351:[DB00480 DB07329] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07329|1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID IGHG2 common genes common pathways 37352:[DB00480 DB05798] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05798|GEM-231 PRKAR2A;PRKAR1A common genes common pathways 37353:[DB00480 DB05533] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05533|QR-333 AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0010033| response to organic substance AKR1B1;PTGS2 37354:[DB00480 DB07733] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07733|1-METHYL-3-TRIFLUOROMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID (2-MERCAPTO-ETHYL)-AMIDE CASP1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CASP1 GO:0050727| regulation of inflammatory response PTGS2;CASP1 GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;TNFSF11 37355:[DB00480 DB14012] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14012|Burosumab FGF23 common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;FGF23 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGF23 GO:0030154| cell differentiation TNFSF11;FGF23 37356:[DB00480 DB07978] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07978|2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0042493| response to drug PTGS2;DHODH;ABCB1 GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0043065| positive regulation of apoptotic process PTGS2;DHODH 37357:[DB00480 DB08735] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08735|R,S-Warfarin alcohol ALB common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 37358:[DB00480 DB11300] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11300|Thrombin F2R;F2RL3;F11;F13A1;F13B;FGA;FGB;FGG;F5;F8 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;F2R GO:0008285| negative regulation of cell proliferation PTGS2;F2R;CDH5 GO:0045907| positive regulation of vasoconstriction FGB;F2R;FGA;PTGS2;FGG GO:0006954| inflammatory response F2R;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;F2R GO:0055114| oxidation-reduction process PTGS2;F8 GO:0008284| positive regulation of cell proliferation F2R;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;F2R 37359:[DB00480 DB00332] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0055085| transmembrane transport SLC22A5;SLC22A4;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 37360:[DB00480 DB05025] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0006979| response to oxidative stress PTGS2;SOD1 GO:0007568| aging PTGS2;SOD1 GO:0010033| response to organic substance SOD1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;SOD1 GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0042493| response to drug ABCB1;SOD1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;SOD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0008217| regulation of blood pressure SOD1;PTGS2 GO:0043065| positive regulation of apoptotic process SOD1;PTGS2 37361:[DB00480 DB06245] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06245|Lanoteplase PLAUR;FGA;KLK1;LAMA5;F10;FN1;SERPINB2;CLEC3B;KRT8;ANXA2;LAMB1;LAMC1;LAMA1;CALR;CANX;LRP1;LAMA3 common genes common pathways GO:0030154| cell differentiation LAMA5;TNFSF11 GO:0045907| positive regulation of vasoconstriction FGA;PTGS2 GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0001525| angiogenesis LAMA5;PTGS2;FN1;ANXA2 GO:0007275| multicellular organismal development LRP1;TNFSF11 GO:0001503| ossification CLEC3B;TNFSF11 GO:0006629| lipid metabolic process PTGS2;LRP1 GO:0009887| organ morphogenesis LAMA5;TNFSF11 GO:0010033| response to organic substance PTGS2;CALR GO:0032355| response to estradiol stimulus PTGS2;CALR GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;KRT8 GO:0098609| ANXA2;CDH5 GO:0030282| bone mineralization CLEC3B;PTGS2 GO:0007568| aging CANX;LRP1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;CALR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 GO:0042127| regulation of cell proliferation PTGS2;LAMA5 GO:0008284| positive regulation of cell proliferation CALR;PTGS2;FN1 GO:0043066| negative regulation of apoptotic process SERPINB2;PLAUR;PTGS2 GO:0007155| cell adhesion CDH5;LAMB1;LAMC1;LAMA1;FN1;LAMA5;LAMA3 37362:[DB00480 DB06780] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37363:[DB00480 DB08010] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08010|(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways 37364:[DB00480 DB02510] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02510|'5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 37365:[DB00480 DB05424] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05424|Canertinib EGFR common genes common pathways GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0001503| ossification EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0014070| response to organic cyclic compound EGFR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGFR GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0006979| response to oxidative stress PTGS2;EGFR GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;EGFR GO:0098609| CDH5;EGFR GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR 37366:[DB00480 DB05219] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05219|Crisaborole PDE4A;PDE4B;PDE4C;PDE4D;CYP2B6;CYP2C8;CYP2C9 common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity PDE4D;TNFSF11 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP2C9;CYP2B6 GO:0006629| lipid metabolic process PTGS2;CYP2C9 37367:[DB00480 DB05469] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05469|R450 ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0045907| positive regulation of vasoconstriction ADRA1D;ADRA1B;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;PTGS2;ADRA1B GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D GO:0007568| aging ADRA1A;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA1D GO:0042493| response to drug PTGS2;ADRA1A;ABCB1 37368:[DB00480 DB03003] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03003|Glutathione Sulfonic Acid gstA;GSTM4;GSTA1;GSTP1 common genes common pathways GO:0098869| GSTA1;PTGS2;GSTP1 GO:0032355| response to estradiol stimulus GSTP1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;GSTP1 37369:[DB00480 DB02750] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways GO:0030154| cell differentiation SLC7A5;TNFSF11 GO:0007275| multicellular organismal development SLC7A5;TNFSF11 GO:0006810| transport SLC7A8;SLC7A5;ABCB1 37370:[DB00480 DB11638] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0010033| response to organic substance PKM;PTGS2 GO:0043406| positive regulation of MAP kinase activity IQGAP1;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;ZYX GO:0000086| G2/M transition of mitotic cell cycle TUBB4A;TUBB;ABCB1;TUBA1A GO:0098869| PTGS2;ALB GO:0006979| response to oxidative stress PRDX1;PTGS2 GO:0098609| ANXA2;CDH5;MYH9;DSP GO:0010469| regulation of receptor activity TNFSF11;GPI GO:0032355| response to estradiol stimulus PTGS2;HNRNPD;GPI GO:0071456| cellular response to hypoxia HP1BP3;PTGS2;PGK1;P4HB;NPEPPS GO:0042493| response to drug PTGS2;HNRNPD;LDHA;SRP14;LGALS1;ABCB1 GO:0034332| adherens junction organization CDH5;DSP GO:0055114| oxidation-reduction process G6PD;GAPDHS;ALDH7A1;CYP2D6;P4HB;LDHB;PRDX1;CYP2C19;LDHA;MDH1;PTGS2;CYCS;FTO;GAPDH GO:0002548| monocyte chemotaxis RPS19;TNFSF11 GO:0043066| negative regulation of apoptotic process RPL10;HNRNPK;FLNA;CFL1;PTGS2;HSPB1;NPM1;ALB;RPS6 GO:0008284| positive regulation of cell proliferation PTGS2;RPS9;NPM1;SHMT2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NPM1;HNRNPK;TNFSF11;SFPQ GO:0007155| cell adhesion CDH5;MYH9;ZYX GO:0042127| regulation of cell proliferation HP1BP3;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;NPM1 GO:0014070| response to organic cyclic compound LDHA;PTGS2;G6PD GO:0034644| cellular response to UV PTGS2;NPM1 GO:0030154| cell differentiation TNFSF11;DPYSL2 GO:0051092| positive regulation of NF-kappaB transcription factor activity NPM1;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;PTGS2 GO:1990776| PTGS2;IQGAP1 GO:0043065| positive regulation of apoptotic process LDHA;PTGS2;RPS6 GO:0050727| regulation of inflammatory response ZYX;PTGS2 GO:0006629| lipid metabolic process G6PD;CYP2D6;PTGS2;UGT2B7 GO:0007275| multicellular organismal development RPL10;TNFSF11;TPI1;DPYSL2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FLNA;LGALS1 GO:0001525| angiogenesis GPI;ANXA2;MYH9;PTGS2 37371:[DB00480 DB01161] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0007612| learning PTGS2;BCHE GO:0042127| regulation of cell proliferation PTGS2;CHRNA10 GO:0042493| response to drug BCHE;ABCB1;SLC6A3;PTGS2 GO:0007568| aging SLC6A3;PTGS2 GO:0055085| transmembrane transport SCN10A;SLC6A3;ABCB1 GO:0019233| sensory perception of pain PTGS2;SCN10A GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 37372:[DB00480 DB01870] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01870|1,4-dithio-alpha-D-glucopyranose AMY2B common genes common pathways 37373:[DB00480 DB06216] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;HTR5A;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11;HTR2B;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HTR2B;HTR2A;DRD3;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2;DRD3;DRD2 GO:0007612| learning PTGS2;DRD1;DRD3 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP1A2;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug HTR2B;PTGS2;ADRA1A;DRD2;DRD1;HTR2A;ABCB1;HTR1B;DRD3;HTR2C;CYP1A2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;HRH2;ADRA1A;HRH1;ADRA2C GO:0045453| bone resorption ADRB2;TNFSF11 GO:0007613| memory DRD1;HTR2A;HRH2;PTGS2;HRH1 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP1A2;CYP3A4 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0006955| immune response HRH2;TNFSF11 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0006954| inflammatory response PTGS2;HRH1 37374:[DB00480 DB07374] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RPL23 GO:0008284| positive regulation of cell proliferation PTGS2;RPL23 37375:[DB00480 DB04882] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04882|Edotecarin TOP1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;TOP1 37376:[DB00480 DB14637] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37377:[DB00480 DB06451] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06451|Aprinocarsen PRKCA common genes common pathways GO:0001525| angiogenesis PRKCA;PTGS2 GO:0045780| positive regulation of bone resorption PRKCA;TNFSF11 GO:0007155| cell adhesion CDH5;PRKCA 37378:[DB00480 DB00228] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ATP2C1 GO:0045332| phospholipid translocation ABCB1;KCNN4 GO:0042493| response to drug GABRG3;ABCB1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055085| transmembrane transport ABCB1;KCNA1 GO:0006810| transport GABRB3;GABRA1;GABRG2;ABCB1;GABRA5;GABRA3;GABRB2;GABRB1;GABRA6;GABRA4;GABRD GO:0051260| protein homooligomerization TNFSF11;GLRA1;KCNA1 GO:0098869| PTGS2;ALB 37379:[DB00480 DB07207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07207|2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE F7;F3 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0051897| positive regulation of protein kinase B signaling cascade F7;TNFSF11;F3 GO:0019221| cytokine-mediated signaling pathway F3;TNFSF11 GO:0014070| response to organic cyclic compound F7;PTGS2 37380:[DB00480 DB08547] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08547|PROGESTERONE-11-ALPHA-OL-HEMISUCCINATE IGHG2 common genes common pathways 37381:[DB00480 DB07488] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07488|{(2Z)-4-AMINO-2-[(4-METHOXYPHENYL)IMINO]-2,3-DIHYDRO-1,3-THIAZOL-5-YL}(4-METHOXYPHENYL)METHANONE CSNK1G3 common genes common pathways 37382:[DB00480 DB07922] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07922|N-oxo-2-(phenylsulfonylamino)ethanamide MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;TNFSF11 37383:[DB00480 DB00663] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37384:[DB00480 DB00801] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;GABRG3 GO:0006810| transport GABRA3;GABRA5;GABRB2;GABRB1;GABRA4;GABRR1;GABRA6;GABRR2;GABRD;GABRB3;GABRA1;GABRG2;ABCB1 37385:[DB00480 DB01282] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01282|Carbetocin OXTR common genes common pathways GO:0032355| response to estradiol stimulus OXTR;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;OXTR GO:0034097| response to cytokine stimulus OXTR;PTGS2 GO:0042493| response to drug OXTR;ABCB1;PTGS2 GO:0045907| positive regulation of vasoconstriction OXTR;PTGS2 GO:0007613| memory OXTR;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;OXTR GO:0070371| ERK1 and ERK2 cascade OXTR;TNFSF11 37386:[DB00480 DB01143] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01143|Amifostine ALPPL2;ENPP1;ALPL common genes common pathways GO:0032496| response to lipopolysaccharide ALPL;PTGS2 GO:0006955| immune response TNFSF11;ENPP1 GO:0033280| response to vitamin D PTGS2;ALPL GO:0051384| response to glucocorticoid stimulus ALPL;PTGS2 37387:[DB00480 DB02715] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02715|Compound 18 ESR1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 37388:[DB00480 DB00226] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0042493| response to drug ABCB1;SLC6A2;PTGS2 37389:[DB00480 DB01373] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0001503| ossification MGP;TNFSF11;BMP4 GO:0050727| regulation of inflammatory response PTGS2;S100A9;S100A8 GO:0043065| positive regulation of apoptotic process S100B;BMP4;PTGS2 GO:0007275| multicellular organismal development TNFSF11;BMP4;MGP GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100A13;TNFSF11;S100B;ATP2C1 GO:0001525| angiogenesis PTGS2;PDCD6;BMP4 GO:0010942| positive regulation of cell death BMP4;PTGS2 GO:0006954| inflammatory response S100A8;S100A9;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;S100A8;S100A9 GO:0007613| memory PTGS2;S100B GO:0030154| cell differentiation MGP;TNFSF11;BMP4 GO:0051384| response to glucocorticoid stimulus S100B;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;BMP4;CDH5 GO:0007155| cell adhesion COMP;CDH5;PCDH19 GO:0043066| negative regulation of apoptotic process PTGS2;BMP4;COMP GO:0045786| negative regulation of cell cycle BMP4;PTGS2 GO:0008284| positive regulation of cell proliferation BMP4;S100B;PTGS2;S100A13 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;BMP4 GO:0032496| response to lipopolysaccharide PTGS2;S100A8 GO:0007156| homophilic cell adhesion CDH5;PCDH19 GO:0048661| positive regulation of smooth muscle cell proliferation BMP4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AOC1;CP GO:0042493| response to drug ABCB1;AOC1;PTGS2 GO:0098869| PTGS2;S100A9 GO:0071456| cellular response to hypoxia PTGS2;S100B GO:0034605| cellular response to heat PDCD6;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;BMP4 GO:0009887| organ morphogenesis TNFSF11;COMP GO:0055085| transmembrane transport ABCB1;CACNA1C;CALM1 37390:[DB00480 DB01321] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01321|Josamycin rplD;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37391:[DB00480 DB01915] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01915|S-Hydroxycysteine C3;GSTP1;ACAT2;GSTA1;PMP2 common genes common pathways GO:0006954| inflammatory response PTGS2;C3 GO:0006955| immune response TNFSF11;C3 GO:0010575| positive regulation vascular endothelial growth factor production C3;PTGS2 GO:0006629| lipid metabolic process ACAT2;C3;PTGS2 GO:0032355| response to estradiol stimulus GSTP1;PTGS2 GO:0098869| GSTP1;PTGS2;GSTA1 GO:0006631| fatty acid metabolic process PTGS2;C3 GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2 37392:[DB00480 DB07593] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07593|1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 37393:[DB00480 DB08361] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways GO:0006954| inflammatory response SYK;PTGS2 GO:0001525| angiogenesis PTGS2;SYK GO:0007257| activation of JUN kinase activity SYK;TNFSF11 GO:0009887| organ morphogenesis SYK;TNFSF11 GO:0045780| positive regulation of bone resorption TNFSF11;SYK 37394:[DB00480 DB07159] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07159|Tamatinib SYK common genes common pathways GO:0007257| activation of JUN kinase activity TNFSF11;SYK GO:0001525| angiogenesis PTGS2;SYK GO:0006954| inflammatory response PTGS2;SYK GO:0045780| positive regulation of bone resorption SYK;TNFSF11 GO:0009887| organ morphogenesis TNFSF11;SYK 37395:[DB00480 DB00114] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0055114| oxidation-reduction process CBS;GLDC;PNPO;PTGS2 GO:0042493| response to drug SRR;GAD1;ABCB1;ABAT;GAD2;PTGS2 GO:0006631| fatty acid metabolic process SGPL1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;SRR GO:0071318| cellular response to ATP PDXP;PTGS2 GO:0008284| positive regulation of cell proliferation ODC1;PTGS2;SHMT2 GO:0043066| negative regulation of apoptotic process CTH;PTGS2 GO:1990830| BCAT2;TNFSF11;SHMT1;CTH;GLDC GO:0007568| aging PTGS2;SRR;ABAT GO:0006979| response to oxidative stress TAT;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;AGXT2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CTH GO:0007275| multicellular organismal development IGSF10;TNFSF11 GO:0001503| ossification TNFSF11;IGSF10 GO:0006629| lipid metabolic process SPTLC3;PTGS2;SPTLC2;SPTLC1;SGPL1 GO:0014070| response to organic cyclic compound PTGS2;SRR;TAT GO:0030154| cell differentiation TNFSF11;IGSF10 GO:0051384| response to glucocorticoid stimulus TAT;AGXT;PTGS2;GOT1 37396:[DB00480 DB02931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02931|Coa-S-Acetyl Tryptamine AANAT common genes common pathways GO:0014070| response to organic cyclic compound AANAT;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT 37397:[DB00480 DB05513] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05513|Atiprimod IL6;TNF common genes common pathways GO:0008285| negative regulation of cell proliferation IL6;CDH5;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;TNF;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;TNF;IL6 GO:0006955| immune response TNF;IL6;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;IL6;TNF GO:0006954| inflammatory response PTGS2;TNF;IL6 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IL6;TNFSF11 GO:0043065| positive regulation of apoptotic process TNF;PTGS2;IL6 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0007275| multicellular organismal development TNFSF11;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0010469| regulation of receptor activity IL6;TNFSF11;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL6 GO:0048661| positive regulation of smooth muscle cell proliferation IL6;TNF;PTGS2 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0002548| monocyte chemotaxis IL6;TNFSF11 GO:0043066| negative regulation of apoptotic process IL6;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;IL6;TNFSF11 GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;TNF 37398:[DB00480 DB11091] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0070542| response to fatty acid PTGS2;CAT GO:0006629| lipid metabolic process GPX1;PTGS2 GO:0009314| response to radiation CAT;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0098869| PTGS2;GPX1;CAT GO:0006979| response to oxidative stress PTGS2;GPX1;CAT GO:0007568| aging PTGS2;CAT GO:0032355| response to estradiol stimulus PTGS2;CAT GO:0043066| negative regulation of apoptotic process CAT;GPX1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNFSF11 GO:0019372| lipoxygenase pathway PTGS2;GPX1 GO:0055114| oxidation-reduction process PTGS2;CAT;GPX1 GO:0042493| response to drug ABCB1;CAT;PTGS2 37399:[DB00480 DB13153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13153|Levomenol SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 37400:[DB00480 DB08340] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08340|N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 37401:[DB00480 DB11640] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNA1 GO:0051260| protein homooligomerization TNFSF11;KCNA1 37402:[DB00480 DB08270] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08270|N-(2-AMINOETHYL)-N~2~-{(1S)-1-[4'-(AMINOSULFONYL)BIPHENYL-4-YL]-2,2,2-TRIFLUOROETHYL}-L-LEUCINAMIDE CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 37403:[DB00480 DB02860] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02860|Calyculin A PPP1CC common genes common pathways 37404:[DB00480 DB00898] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0030154| cell differentiation L1CAM;TNFSF11 GO:0007613| memory PTGS2;CHRNA7;CHRNB2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2C9;CYP3A4 GO:0007275| multicellular organismal development L1CAM;TNFSF11 GO:0019233| sensory perception of pain PTGS2;CHRNA4;CHRNB2 GO:0051260| protein homooligomerization GLRA1;TNFSF11 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0071456| cellular response to hypoxia SLC29A1;PTGS2 GO:0007568| aging VCAM1;PTGS2;CYP1A1 GO:0006810| transport CHRNB3;ABCB1;GABRA1;GABRB3;GRIA4;GABRA6;GABRA4;CHRNA6;GRIA3;CACNG2;GABRB1;GABRD;CACNB1;CACNG1;GABRB2;GABRA3;GABRA5 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0098609| CDH5;VCAM1 GO:0010033| response to organic substance CYP1A1;PTGS2;CYP1A2 GO:0055085| transmembrane transport CACNA1D;CACNA1C;CACNA1S;ABCB1 GO:0007155| cell adhesion L1CAM;CDH5;VCAM1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;CHRNA10 GO:0007612| learning PTGS2;CHRNB2 GO:0032496| response to lipopolysaccharide CYP1A1;VCAM1;PTGS2;CYP1A2;ADH5 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP1A2;ADH1A;ADH5;CYP3A4;ADH1C;ADH4;ADH6;CYP1A1;ADH7;CYP4A11;CYP2E1;ADH1B;AKR1A1;CYP2C19;PTGS2;VCAM1 GO:0042493| response to drug ABCB1;GABRG3;CYP1A2;PTGS2;CYP1A1;CYP2E1 GO:0006631| fatty acid metabolic process PTGS2;CYP4A11 37405:[DB00480 DB00197] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0001525| angiogenesis PTGS2;SERPINE1 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PPARA;PPARD;PPARG;UGT2B7;ACSL4;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;CYP1A1;PPARG GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0030154| cell differentiation TNFSF11;PPARD GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0007566| embryo implantation PPARD;PTGS2 GO:0055114| oxidation-reduction process CYP3A7;CYP3A5;CYP1A1;PTGS2;CYP2C8;CYP2C19;CYP19A1;CYP2C9;CYP2B6;CYP3A4 GO:0042493| response to drug CYP1A1;PTGS2;UGT1A1;PPARG;ABCB1 GO:0006631| fatty acid metabolic process UGT1A7;UGT1A8;PPARA;ACSL4;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA;PPARD GO:0042127| regulation of cell proliferation ESRRA;PTGS2;PPARD GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;CYP1A1 GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINE1;ESRRG;ESRRA;PPARA;PPARG;TNFSF11 GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2;PPARD GO:0055085| transmembrane transport ABCB1;SLCO1B1;ABCB11 GO:0010033| response to organic substance PPARG;PPARD;CYP1A1;UGT1A1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SLC29A1;PPARD GO:0007568| aging PTGS2;CYP1A1 GO:0046697| decidualization PPARD;PTGS2 GO:0006810| transport ABCB11;ABCB1 GO:0032355| response to estradiol stimulus GSTP1;ESRRA;PTGS2 GO:0010469| regulation of receptor activity SERPINE1;TNFSF11 GO:0045670| regulation of osteoclast differentiation ESRRA;TNFSF11 GO:0098869| PTGS2;GSTP1 37406:[DB00480 DB01186] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2A;HTR2B GO:0007568| aging PTGS2;HTR2A;ADRA1A GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug HTR2A;DRD1;DRD2;ADRA1A;PTGS2;HTR2B;HTR2C;DRD3;HTR1B;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11;DRD3 GO:0008284| positive regulation of cell proliferation ADRA1D;DRD3;ADRA2A;HTR2B;PTGS2;HTR1A;HTR2A GO:0007612| learning PTGS2;DRD1;DRD5;DRD3 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;ADRA1B;PTGS2;ADRA1D GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction ADRA1D;ADRA2C;PTGS2;ADRA1B;HTR2A;ADRA1A GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0007613| memory PTGS2;HTR2A;DRD1 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 37407:[DB00480 DB00020] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00020|Sargramostim CSF2RA;IL3RA;CSF2RB;SDC2;PRG2 common genes common pathways GO:0032496| response to lipopolysaccharide CSF2RB;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;CSF2RA;CSF2RB;IL3RA GO:0030154| cell differentiation SDC2;TNFSF11 GO:0006955| immune response TNFSF11;PRG2 37408:[DB00480 DB03193] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03193|Stearic acid PLA2G2D;PPARA;FABP3;ALB common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0006631| fatty acid metabolic process FABP3;PPARA;PTGS2 GO:0042493| response to drug ABCB1;FABP3;PTGS2 GO:0070542| response to fatty acid PTGS2;FABP3 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;FABP3 GO:0006629| lipid metabolic process PTGS2;PLA2G2D;PPARA GO:0006954| inflammatory response PTGS2;PLA2G2D 37409:[DB00480 DB02258] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02258|SR11254 RARG common genes common pathways GO:1990830| TNFSF11;RARG GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;RARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RARG 37410:[DB00480 DB11569] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11569|Ixekizumab IL17A common genes common pathways GO:0045672| positive regulation of osteoclast differentiation IL17A;TNFSF11 GO:0006955| immune response IL17A;TNFSF11 GO:0006954| inflammatory response IL17A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL17A;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;IL17A 37411:[DB00480 DB06345] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06345|AR-9281 EPHX2 common genes common pathways GO:0006954| inflammatory response PTGS2;EPHX2 GO:0006629| lipid metabolic process EPHX2;PTGS2 GO:0008217| regulation of blood pressure EPHX2;PTGS2 37412:[DB00480 DB08738] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08738|1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one PREP common genes common pathways 37413:[DB00480 DB01130] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 37414:[DB00480 DB06151] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0010033| response to organic substance CHUK;PTGS2 GO:0055085| transmembrane transport SLC22A6;SLCO1B1;ABCB1 GO:0034612| response to tumor necrosis factor PTGS2;GSS GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006979| response to oxidative stress SLC7A11;PTGS2;GSS GO:0006810| transport ABCB1;GRIN2B;GRIN2A GO:0007568| aging PTGS2;GSS GO:0033209| tumor necrosis factor-mediated signaling pathway IKBKB;CHUK;TNFSF11 GO:0042493| response to drug CHUK;GRIN2A;ABCB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;CHUK;IKBKB;GRIN1 GO:0043066| negative regulation of apoptotic process PTGS2;IKBKB GO:0032496| response to lipopolysaccharide CHUK;PTGS2 GO:0007612| learning GRIN1;PTGS2;GRIN2A GO:0007613| memory GRIN2A;GRIN1;PTGS2 GO:0019722| calcium-mediated signaling GRIN1;GRIN2D;TNFSF11;GRIN2B;GRIN2A GO:0006954| inflammatory response PTGS2;IKBKB;CHUK GO:0051092| positive regulation of NF-kappaB transcription factor activity CHUK;TNFSF11;IKBKB GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0006955| immune response CHUK;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;GRIN1;GRIN2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IKBKB;TNFSF11;CHUK GO:0019233| sensory perception of pain GRIN2A;PTGS2;GRIN1 37415:[DB00480 DB07125] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07125|4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid DAPK3 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;DAPK3 37416:[DB00480 DB03704] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03704|12-Hydroxydodecanoic Acid ADH5 common genes common pathways GO:0055114| oxidation-reduction process ADH5;PTGS2 GO:0032496| response to lipopolysaccharide ADH5;PTGS2 37417:[DB00480 DB06634] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;TACR1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0008217| regulation of blood pressure TACR1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;TACR1 GO:0045907| positive regulation of vasoconstriction TACR1;PTGS2 GO:0006954| inflammatory response PTGS2;TACR1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0019233| sensory perception of pain PTGS2;TACR1 37418:[DB00480 DB05024] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05024|CTA018 CYP24A1;VDR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 GO:0055114| oxidation-reduction process CYP24A1;PTGS2 GO:0046697| decidualization PTGS2;VDR GO:0009887| organ morphogenesis TNFSF11;VDR GO:0007275| multicellular organismal development TNFSF11;VDR GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;VDR GO:0033280| response to vitamin D PTGS2;CYP24A1 37419:[DB00480 DB08869] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08869|Tesamorelin GHRHR common genes common pathways GO:0008284| positive regulation of cell proliferation GHRHR;PTGS2 GO:0051384| response to glucocorticoid stimulus GHRHR;PTGS2 37420:[DB00480 DB08676] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08676|(20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIAZACYCLONOADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CDH5 GO:0042127| regulation of cell proliferation PTGS2;FNTB 37421:[DB00480 DB08815] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2A GO:0007568| aging PTGS2;HTR2A GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug HTR2A;DRD2;PTGS2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HTR2A;ADRA2A GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction ADRA2C;HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A 37422:[DB00480 DB03509] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03509|2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide PARP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5 37423:[DB00480 DB00400] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;CYP2D6;CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 37424:[DB00480 DB07465] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07465|(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion CDH5;DPP4 37425:[DB00480 DB03507] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03507|6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One TNFRSF1A common genes common pathways GO:0006954| inflammatory response PTGS2;TNFRSF1A GO:0006955| immune response TNFRSF1A;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFRSF1A;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;TNFRSF1A GO:0006693| prostaglandin metabolic process TNFRSF1A;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNFRSF1A GO:0019221| cytokine-mediated signaling pathway TNFRSF1A;TNFSF11 GO:0050728| negative regulation of inflammatory response TNFRSF1A;CDH5 GO:0032496| response to lipopolysaccharide TNFRSF1A;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;TNFRSF1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TNFRSF1A 37426:[DB00480 DB07662] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07662|N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE SRC;EGFR common genes common pathways GO:0042327| positive regulation of phosphorylation TNFSF11;EGFR GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification EGFR;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;EGFR GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0045453| bone resorption TNFSF11;SRC GO:0070542| response to fatty acid PTGS2;SRC GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0014070| response to organic cyclic compound PTGS2;EGFR GO:0043066| negative regulation of apoptotic process SRC;EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0007155| cell adhesion SRC;CDH5 GO:0042127| regulation of cell proliferation PTGS2;EGFR;SRC GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR;SRC GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0034332| adherens junction organization CDH5;SRC GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0006979| response to oxidative stress EGFR;PTGS2 GO:1902533| TNFSF11;SRC GO:0098609| EGFR;SRC;CDH5 GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0032355| response to estradiol stimulus PTGS2;EGFR GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC;EGFR GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 37427:[DB00480 DB06422] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06422|Ticalopride HTR4;HTR3A common genes common pathways 37428:[DB00480 DB05869] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05869|Ethyl pyruvate TNF;HMGB1 common genes common pathways GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0010033| response to organic substance PTGS2;TNF GO:0010469| regulation of receptor activity TNFSF11;TNF;HMGB1 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2 GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0046330| positive regulation of JNK cascade HMGB1;TNF;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HMGB1;TNF;TNFSF11 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0006954| inflammatory response HMGB1;TNF;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0006955| immune response TNF;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0043065| positive regulation of apoptotic process TNF;PTGS2;HMGB1 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0045672| positive regulation of osteoclast differentiation TNF;TNFSF11 37429:[DB00480 DB01629] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0010033| response to organic substance PTGS2;SOD1 GO:0006979| response to oxidative stress SOD1;PTGS2 GO:0007568| aging SOD1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;SOD1 GO:0042493| response to drug PTGS2;SOD1;ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;SOD1 GO:0071318| cellular response to ATP SOD1;PTGS2 GO:0008217| regulation of blood pressure SOD1;PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0043065| positive regulation of apoptotic process SOD1;PTGS2 37430:[DB00480 DB12478] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0042493| response to drug DRD3;ABCB1;PTGS2;DRD2 GO:0007612| learning PTGS2;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;DRD3 37431:[DB00480 DB02936] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02936|4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;PTGS2 37432:[DB00480 DB02148] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02148|3-Amino-4-Oxybenzyl-2-Butanone CTSB common genes common pathways GO:0046697| decidualization CTSB;PTGS2 37433:[DB00480 DB02335] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02335|2-Aminothiazoline NOS3 common genes common pathways GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 37434:[DB00480 DB07387] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07387|3-(BUTYLSULPHONYL)-PROPANOIC ACID TPI1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;TPI1 37435:[DB00480 DB00824] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2 GO:0006954| inflammatory response ADORA3;PTGS2;ADORA2A;ADORA1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;ADORA2B GO:0008285| negative regulation of cell proliferation ADORA3;ADORA2A;PTGS2;CDH5;ADORA1 GO:0042493| response to drug ADORA2A;PTGS2;ABCB1 GO:0050728| negative regulation of inflammatory response CDH5;ADORA1;ADORA2A GO:0043066| negative regulation of apoptotic process PTGS2;ADORA1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0097756| ADORA1;PTGS2 37436:[DB00480 DB03175] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03175|Propyl alcohol LYZ common genes common pathways GO:0006954| inflammatory response LYZ;PTGS2 37437:[DB00480 DB11834] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11834|Guselkumab IL23A common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;IL23A GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL23A;TNFSF11 GO:0006955| immune response TNFSF11;IL23A GO:0006954| inflammatory response IL23A;PTGS2 GO:0045672| positive regulation of osteoclast differentiation IL23A;TNFSF11 37438:[DB00480 DB02318] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02318|2-deoxy-2-fluoro-alpha-D-mannosyl fluoride MAN2A1 common genes common pathways 37439:[DB00480 DB00848] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00848|Levamisole CHRNA3;ALPPL2 common genes common pathways 37440:[DB00480 DB04947] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04947|Altropane SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A3;PTGS2;ABCB1 GO:0007568| aging SLC6A3;PTGS2 GO:0055085| transmembrane transport SLC6A3;ABCB1 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 37441:[DB00480 DB01860] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01860|Cordycepin Triphosphate PAPOLA common genes common pathways 37442:[DB00480 DB04080] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04080|RU78191 SRC common genes common pathways GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0034332| adherens junction organization SRC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0098609| CDH5;SRC GO:0071456| cellular response to hypoxia PTGS2;SRC GO:1902533| SRC;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0070542| response to fatty acid SRC;PTGS2 37443:[DB00480 DB02917] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02917|N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide HDAC8 common genes common pathways 37444:[DB00480 DB11124] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0045453| bone resorption TNFSF11;ADRB2 GO:0045907| positive regulation of vasoconstriction ADRA1D;ADRA2C;ADRA1B;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1B;PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0050873| brown fat cell differentiation ADRB3;PTGS2;ADRB1;ADRB2 GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D GO:0007568| aging PTGS2;ADRA1A;ADRB3 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA2A;ADRA1D;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0042493| response to drug PTGS2;ADRA1A;ABCB1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 37445:[DB00480 DB02226] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02226|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 37446:[DB00480 DB09018] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09018|Bromopride DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0042493| response to drug PTGS2;DRD2;ABCB1 37447:[DB00480 DB01096] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01096|Oxamniquine CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006629| lipid metabolic process PTGS2;CYP2D6 37448:[DB00480 DB06587] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37449:[DB00480 DB05990] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05990|Obeticholic acid NR1H4;BAAT;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2;BAAT GO:0006954| inflammatory response NR1H4;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;NR1H4 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0050728| negative regulation of inflammatory response NR1H4;CDH5 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0006631| fatty acid metabolic process BAAT;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0007043| cell-cell junction assembly NR1H4;CDH5 37450:[DB00480 DB06061] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06061|AZD-8330 MAP3K1 common genes common pathways GO:0071260| cellular response to mechanical stimulus MAP3K1;PTGS2 37451:[DB00480 DB05797] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05797|TNX-901 FCER1A common genes common pathways 37452:[DB00480 DB04700] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04700|GLUTATHIONE SULFINATE GSTK1 common genes common pathways GO:0098869| GSTK1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;GSTK1 37453:[DB00480 DB04593] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04593|3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F7 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0014070| response to organic cyclic compound F7;PTGS2 37454:[DB00480 DB08054] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08054|1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:1902533| SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN 37455:[DB00480 DB03082] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03082|6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide PLAU common genes common pathways GO:0042127| regulation of cell proliferation PLAU;PTGS2 GO:0010469| regulation of receptor activity PLAU;TNFSF11 37456:[DB00480 DB02209] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways GO:0008284| positive regulation of cell proliferation ODC1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;PNPO 37457:[DB00480 DB05088] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05088|Tiomolibdate ion APP common genes common pathways GO:0051260| protein homooligomerization APP;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;APP GO:0006979| response to oxidative stress PTGS2;APP GO:0007155| cell adhesion APP;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;APP GO:0046330| positive regulation of JNK cascade TNFSF11;APP GO:0007612| learning APP;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;APP GO:0007613| memory PTGS2;APP GO:0019722| calcium-mediated signaling APP;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;APP;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP 37458:[DB00480 DB04351] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04351|Aconitate Ion ACO2 common genes common pathways 37459:[DB00480 DB08590] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08590|1-(3-HYDROXYPROPYL)-2-[(3-NITROBENZOYL)AMINO]-1H-BENZIMIDAZOL-5-YL PIVALATE IRAK4 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;IRAK4 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IRAK4 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IRAK4 GO:0048661| positive regulation of smooth muscle cell proliferation IRAK4;PTGS2 37460:[DB00480 DB05749] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05749|MPI-674 CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP19A1 37461:[DB00480 DB09363] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC18A2;SLC6A2;ABCB1 GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0042493| response to drug PTGS2;SLC6A2;MAOB;ABCB1 GO:0055114| oxidation-reduction process MAOB;MAOA;PTGS2 37462:[DB00480 DB00912] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0098869| ALB;PTGS2 GO:0006810| transport ABCB1;ABCB11 GO:0010033| response to organic substance PPARG;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCC8;ABCB11;SLCO1B1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0032496| response to lipopolysaccharide PTGS2;ABCC8 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP3A4 GO:0042493| response to drug ABCB1;PPARG;PTGS2;ABCC8 GO:0007613| memory ABCC8;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 37463:[DB00480 DB04888] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0042493| response to drug DRD2;PTGS2;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 37464:[DB00480 DB01858] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01858|[1-(4-Fluorobenzyl)Cyclobutyl]Methyl (1s)-1-[Oxo(1h-Pyrazol-5-Ylamino)Acetyl]Pentylcarbamate CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 37465:[DB00480 DB14010] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0042493| response to drug HTR2A;PTGS2;ABCB1 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging PTGS2;HTR2A GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0007613| memory HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A 37466:[DB00480 DB01256] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01256|Retapamulin rplC;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37467:[DB00480 DB00944] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00944|Demecarium ACHE;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0007155| cell adhesion ACHE;CDH5 37468:[DB00480 DB04345] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04345|7,8-dimethylalloxazine BLVRB common genes common pathways GO:0055114| oxidation-reduction process PTGS2;BLVRB 37469:[DB00480 DB04836] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0007613| memory SLC6A4;PTGS2 GO:0042493| response to drug SLC6A4;ABCB1;PTGS2;SLC6A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 37470:[DB00480 DB13192] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13192|Antihemophilic factor human F9;F10;PROC common genes common pathways GO:0043066| negative regulation of apoptotic process PROC;PTGS2 GO:0050728| negative regulation of inflammatory response PROC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 GO:1903142| CDH5;PROC 37471:[DB00480 DB00211] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2;ADRA1B;ADRA1D GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction ADRA1A;ADRA1B;PTGS2;ADRA1D GO:0042493| response to drug ABCB1;ADRA1A;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0008284| positive regulation of cell proliferation ADRA1D;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC15A1 GO:0007568| aging PTGS2;ADRA1A GO:0006810| transport SLC15A1;ABCB1 37472:[DB00480 DB01564] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01564|Calusterone AR common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0006810| transport ABCB1;AR GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR 37473:[DB00480 DB03058] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03058|2-Aminobenzyl alcohol CFD common genes common pathways 37474:[DB00480 DB05005] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05005|CCX282 CCR9 common genes common pathways GO:0006955| immune response CCR9;TNFSF11 37475:[DB00480 DB08008] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08008|5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHODH GO:0042493| response to drug ABCB1;DHODH;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 37476:[DB00480 DB08063] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08063|1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE RXRA;NR1H3 common genes common pathways GO:0007566| embryo implantation RXRA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;TNFSF11;RXRA GO:0050728| negative regulation of inflammatory response NR1H3;CDH5 37477:[DB00480 DB01754] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01754|3,4-Dihydroxy-1-Methylquinolin-2(1h)-One PIM1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2 37478:[DB00480 DB03686] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03686|S-(P-Nitrobenzyl)Glutathione GSTP1 common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;GSTP1 GO:0098869| GSTP1;PTGS2 37479:[DB00480 DB03309] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03309|N-Cyclohexyltaurine EN2;rph;SULT2B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EN2 GO:0007275| multicellular organismal development TNFSF11;EN2 GO:0006629| lipid metabolic process SULT2B1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;SULT2B1;PTGS2 37480:[DB00480 DB08118] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08118|2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 37481:[DB00480 DB04003] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04003|{4-[(2S)-2-Acetamido-3-({(1S)-1-[3-carbamoyl-4-(cyclohexylmethoxy)phenyl]ethyl}amino)-3-oxopropyl]-2-phosphonophenoxy}acetic acid LCK common genes common pathways GO:0042493| response to drug PTGS2;LCK;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade LCK;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;LCK GO:0050870| positive regulation of T cell activation LCK;TNFSF11 37482:[DB00480 DB04767] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04767|N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID F7 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;F7 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0051897| positive regulation of protein kinase B signaling cascade F7;TNFSF11 37483:[DB00480 DB04579] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04579|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}- CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 37484:[DB00480 DB07195] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07195|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11;NCOA2 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 37485:[DB00480 DB05885] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0008217| regulation of blood pressure CACNA1B;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0051260| protein homooligomerization GLRA1;TNFSF11 GO:0006810| transport CACNA1B;ABCB1 GO:0055085| transmembrane transport ABCB1;SV2A;CACNA1B 37486:[DB00480 DB08430] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08430|PARA-NITROPHENYL 1-THIO-BETA-D-GLUCOPYRANOSIDE LCTL common genes common pathways 37487:[DB00480 DB03429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03429|Cardiolipin SLC25A4 common genes common pathways GO:0006810| transport SLC25A4;ABCB1 GO:0055085| transmembrane transport SLC25A4;ABCB1 37488:[DB00480 DB04417] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04417|P-Nitrophenol SULT1A1;AMY2B common genes common pathways GO:0006629| lipid metabolic process PTGS2;SULT1A1 37489:[DB00480 DB08388] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08388|5-(2-ETHOXYETHYL)-5-[4-(4-FLUOROPHENOXY)PHENOXY]PYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13 37490:[DB00480 DB08588] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08588|2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 37491:[DB00480 DB08504] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08504|6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion CDH5;DPP4 37492:[DB00480 DB03696] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03696|Lanosterol LSS common genes common pathways GO:0006629| lipid metabolic process LSS;PTGS2 37493:[DB00480 DB06013] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06013|Aldoxorubicin TOP2A common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 37494:[DB00480 DB05968] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05968|PR-104 TNF common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0006954| inflammatory response PTGS2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TNFSF11 GO:0006955| immune response TNF;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0043065| positive regulation of apoptotic process PTGS2;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNF;TNFSF11 GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0010033| response to organic substance PTGS2;TNF GO:0009887| organ morphogenesis TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0010469| regulation of receptor activity TNF;TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;TNFSF11 GO:0046330| positive regulation of JNK cascade TNFSF11;TNF GO:0042127| regulation of cell proliferation PTGS2;TNF 37495:[DB00480 DB01919] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01919|Pentanal PRKACA common genes common pathways GO:0034605| cellular response to heat PTGS2;PRKACA GO:0000086| G2/M transition of mitotic cell cycle PRKACA;ABCB1 37496:[DB00480 DB14004] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0006631| fatty acid metabolic process CYP4A11;PTGS2 GO:0055114| oxidation-reduction process CYP4A11;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL23A;TNFSF11 GO:0010033| response to organic substance PTGS2;IL12B GO:0010469| regulation of receptor activity TNFSF11;IL23A;IL12B GO:0006954| inflammatory response IL23A;PTGS2 GO:0006955| immune response TNFSF11;IL23A GO:0019233| sensory perception of pain PTGS2;IL12B GO:0045672| positive regulation of osteoclast differentiation IL12B;TNFSF11;IL23A 37497:[DB00480 DB00708] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006955| immune response TNFSF11;OPRK1;OPRD1 GO:0019233| sensory perception of pain PTGS2;OPRD1;OPRM1;OPRK1 GO:0009314| response to radiation PTGS2;OPRM1;OPRK1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37498:[DB00480 DB02401] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02401|4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid LDHB common genes common pathways GO:0055114| oxidation-reduction process LDHB;PTGS2 37499:[DB00480 DB03167] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03167|Pentabromophenol TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TTR;TNFSF11 37500:[DB00480 DB05786] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05786|Irofulven FUBP1 common genes common pathways 37501:[DB00480 DB02279] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02279|Benzoylformic Acid HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;PTGS2 GO:0055114| oxidation-reduction process HAO1;PTGS2 37502:[DB00480 DB00822] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;ALDH2;CYP2E1;DBH;CYP3A5;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0042127| regulation of cell proliferation DBH;PTGS2 GO:0055085| transmembrane transport ABCB11;ABCB1 GO:0006810| transport ABCB11;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007613| memory DBH;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;DBH 37503:[DB00480 DB08338] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08338|19-(cyclopropylamino)-4,6,7,15-tetrahydro-5H-16,1-(azenometheno)-10,14-(metheno)pyrazolo[4,3-o][1,3,9]triazacyclohexadecin-8(9H)-one CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 GO:0008284| positive regulation of cell proliferation CSNK2A1;PTGS2 37504:[DB00480 DB04172] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04172|[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine PLAU common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PLAU GO:0042127| regulation of cell proliferation PTGS2;PLAU 37505:[DB00480 DB06907] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06907|2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport ABCB1;TTR 37506:[DB00480 DB04217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04217|L-2-amino-3-butynoic acid CTH;sufS common genes common pathways GO:1990830| TNFSF11;CTH GO:0043066| negative regulation of apoptotic process PTGS2;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CTH 37507:[DB00480 DB05014] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0010243| response to organic nitrogen PTGS2;FLT3 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PDGFRB GO:0007156| homophilic cell adhesion RET;CDH5 GO:0019221| cytokine-mediated signaling pathway TNFSF11;FLT3 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGFR3;PDGFRB;FGFR1 GO:0042493| response to drug ABCB1;RET;PTGS2 GO:0008284| positive regulation of cell proliferation KDR;FGFR1;PTGS2;PDGFRB;FGFR3;FLT3 GO:0043066| negative regulation of apoptotic process PDGFRB;PTGS2;KDR GO:0007155| cell adhesion RET;CDH5 GO:0042127| regulation of cell proliferation PTGS2;FGFR1 GO:0043406| positive regulation of MAP kinase activity FGFR1;PDGFRB;TNFSF11;FLT3 GO:0032355| response to estradiol stimulus PDGFRB;PTGS2 GO:0030282| bone mineralization PTGS2;FGFR3 GO:0007568| aging PTGS2;PDGFRB GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0043065| positive regulation of apoptotic process PTGS2;PDGFRB GO:0001525| angiogenesis PTGS2;FGFR1;KDR GO:0007275| multicellular organismal development KDR;TNFSF11;PDGFRB GO:0014070| response to organic cyclic compound PDGFRB;PTGS2 GO:0030154| cell differentiation TNFSF11;FLT3;KDR 37508:[DB00480 DB07713] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07713|(1S)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid MMP8 common genes common pathways 37509:[DB00480 DB11590] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11590|Thimerosal MTR;SLC7A11;FXYD2;GSR;GPX1;SOD2;ALB;ITPR1 common genes common pathways GO:0006629| lipid metabolic process GPX1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0008217| regulation of blood pressure SOD2;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;SOD2 GO:0042127| regulation of cell proliferation PTGS2;FXYD2 GO:0043066| negative regulation of apoptotic process GPX1;PTGS2;ALB GO:0055114| oxidation-reduction process GPX1;GSR;PTGS2;SOD2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;GPX1 GO:0019372| lipoxygenase pathway PTGS2;GPX1 GO:0006810| transport FXYD2;ABCB1 GO:0098869| ALB;PTGS2;GSR;GPX1 GO:0006979| response to oxidative stress PTGS2;SLC7A11;GPX1 GO:0055085| transmembrane transport ABCB1;ITPR1 37510:[DB00480 DB08607] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08607|(5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE CYP2C8;FABP4 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0055114| oxidation-reduction process PTGS2;CYP2C8 37511:[DB00480 DB02153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02153|3-Sulfinoalanine PAPOLA;aroH;GSR;PRDX2;def;FABP4 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0055114| oxidation-reduction process GSR;PRDX2;PTGS2 GO:0043066| negative regulation of apoptotic process PRDX2;PTGS2 GO:0006979| response to oxidative stress PRDX2;PTGS2 GO:0098869| GSR;PTGS2 37512:[DB00480 DB06481] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06481|Manitimus DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0042493| response to drug ABCB1;DHODH;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0014070| response to organic cyclic compound DHODH;PTGS2 37513:[DB00480 DB00215] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes ABCB1 common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A;HRH1 GO:0007613| memory PTGS2;HRH1;SLC6A4 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2;CYP2D6 GO:0006954| inflammatory response PTGS2;HRH1 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0007568| aging ADRA1A;SLC6A3;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;SLC6A4 GO:0010033| response to organic substance PTGS2;CYP1A2;SLC6A4 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLC6A3;SLC6A2;SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;PTGS2;CYP2B6;CYP2D6;CYP1A2;CYP3A4 GO:0042493| response to drug SLC6A4;ABCB1;CYP1A2;HTR2C;PTGS2;SLC6A2;CYP2E1;SLC6A3;ADRA1A 37514:[DB00480 DB00250] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes PTGS2 common pathways GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0032496| response to lipopolysaccharide PTGS2;MPO GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;MPO GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP3A5;FMO3;MPO;PTGS1;CYP2E1;CYP3A7;CYP2C19;CYP2C8;CYP2C18;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging PTGS2;MPO GO:0006979| response to oxidative stress MPO;PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2;PTGS1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 37515:[DB00480 DB07015] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07015|(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion DPP4;CDH5 37516:[DB00480 DB00167] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00167|L-Isoleucine IARS2;ACADSB;BCAT1;BCAT2;IARS;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:1990830| BCAT2;TNFSF11 GO:0055114| oxidation-reduction process ACADSB;PTGS2 GO:0006631| fatty acid metabolic process ACADSB;PTGS2 GO:0006629| lipid metabolic process PTGS2;ACADSB 37517:[DB00480 DB02459] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02459|4-Guanidinobenzoic Acid CFB common genes common pathways 37518:[DB00480 DB03845] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03845|P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate DTYMK common genes common pathways 37519:[DB00480 DB00241] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007613| memory PTGS2;CHRNA7 GO:0019233| sensory perception of pain CHRNA4;PTGS2 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0006810| transport GABRA3;GABRA5;GABRB2;GABRD;GABRB1;GABRA6;GRIK2;GABRA4;GABRB3;GABRA1;ABCB1;GABRG2 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0042493| response to drug ABCB1;GABRG3;PTGS2 37520:[DB00480 DB02638] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02638|Terlipressin AVPR2;AVPR1B;AVPR1A common genes common pathways GO:0045907| positive regulation of vasoconstriction AVPR2;AVPR1A;PTGS2;AVPR1B GO:0019722| calcium-mediated signaling TNFSF11;AVPR1A GO:0031394| positive regulation of prostaglandin biosynthetic process AVPR1A;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;AVPR1A;AVPR2 GO:0034097| response to cytokine stimulus AVPR2;PTGS2 GO:0010033| response to organic substance AVPR1A;PTGS2 37521:[DB00480 DB05159] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05159|CCX915 CCR2 common genes common pathways GO:0019221| cytokine-mediated signaling pathway TNFSF11;CCR2 GO:0002548| monocyte chemotaxis CCR2;TNFSF11 GO:0019233| sensory perception of pain PTGS2;CCR2 GO:0006954| inflammatory response CCR2;PTGS2 GO:0006955| immune response CCR2;TNFSF11 GO:0050870| positive regulation of T cell activation CCR2;TNFSF11 37522:[DB00480 DB06069] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06069|XMT-1001 TOP1 common genes common pathways GO:0042493| response to drug PTGS2;TOP1;ABCB1 37523:[DB00480 DB02074] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02074|Butenoic Acid FABP1 common genes common pathways GO:0043066| negative regulation of apoptotic process FABP1;PTGS2 GO:0098869| FABP1;PTGS2 GO:0071456| cellular response to hypoxia FABP1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process FABP1;PTGS2 37524:[DB00480 DB14033] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14033|Acetyl sulfisoxazole CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2C9 37525:[DB00480 DB05712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05712|AZD-9684 CPB2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;CPB2 37526:[DB00480 DB00467] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 37527:[DB00480 DB07013] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07013|TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE MMP13 common genes common pathways GO:0030282| bone mineralization MMP13;PTGS2 37528:[DB00480 DB08837] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A3;SLC47A1;SLC22A1;ABCB1;SLC22A5;SLC22A2 GO:0051260| protein homooligomerization KCNA1;SLC22A1;TNFSF11 GO:0055085| transmembrane transport SLC22A5;SLC22A8;SLC22A2;SLC22A4;SLC22A1;KCNA1;ABCB1;SLC22A3;SLC47A1 37529:[DB00480 DB00187] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00187|Esmolol ADRB1;CYP2D6 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;ADRB1 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 37530:[DB00480 DB03336] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03336|BIA COMT common genes common pathways GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0007612| learning COMT;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;COMT GO:0014070| response to organic cyclic compound COMT;PTGS2 37531:[DB00480 DB12693] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory PTGS2;HTR2A GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging HTR2A;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0042493| response to drug ABCB1;HTR2A;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A 37532:[DB00480 DB04715] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04715|IMIDAZOPYRIDAZIN 1 PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PIM1 GO:0007275| multicellular organismal development PIM1;TNFSF11 37533:[DB00480 DB09124] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11 GO:0098869| ALB;PTGS2 GO:0038001| paracrine signaling TNFSF11;PGR GO:0006629| lipid metabolic process PTGS2;CYP3A4 37534:[DB00480 DB06892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06892|(5S)-4,5-difluoro-6-[(2-fluoro-4-iodophenyl)imino]-N-(2-hydroxyethoxy)cyclohexa-1,3-diene-1-carboxamide MAP2K1 common genes common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAP2K1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;MAP2K1 37535:[DB00480 DB05553] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05553|Regrelor P2RY12 common genes common pathways GO:0071318| cellular response to ATP P2RY12;PTGS2 37536:[DB00480 DB14031] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14031|Tretamine BCHE common genes common pathways GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 37537:[DB00480 DB05045] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05045|Obinepitide NPY4R;NPY2R common genes common pathways GO:0007568| aging NPY2R;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;NPY2R 37538:[DB00480 DB08672] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08672|4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion DPP4;CDH5 37539:[DB00480 DB01863] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01863|Inositol 1,3,4,5-Tetrakisphosphate AKT1;PLEKHA4;BTK;DAPP1;ITPKA;CYTH2;CYTH3;PDPK1 common genes common pathways GO:0016567| protein ubiquitination AKT1;CRBN GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKT1 GO:0042127| regulation of cell proliferation PTGS2;BTK GO:0043066| negative regulation of apoptotic process AKT1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;AKT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AKT1 GO:0010033| response to organic substance AKT1;PTGS2;BTK GO:0007568| aging PTGS2;AKT1 GO:0071456| cellular response to hypoxia PTGS2;AKT1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;AKT1 GO:0006979| response to oxidative stress AKT1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;AKT1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;AKT1 GO:0006954| inflammatory response PTGS2;AKT1 GO:0051092| positive regulation of NF-kappaB transcription factor activity BTK;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;AKT1 GO:0071260| cellular response to mechanical stimulus AKT1;PTGS2 GO:0043065| positive regulation of apoptotic process AKT1;PTGS2 GO:0030154| cell differentiation AKT1;TNFSF11 GO:0019722| calcium-mediated signaling PDPK1;TNFSF11;BTK GO:0033138| positive regulation of peptidyl-serine phosphorylation AKT1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;AKT1 37540:[DB00480 DB07176] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07176|5-aminonaphthalene-1-sulfonic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TNFSF11;TTR 37541:[DB00480 DB08515] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08515|(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE PSMA1;PSMA2;PSMA3;PSMA4;PSMA5;PSMA6;PSMA7;PSMB1;PSMB2;PSMB3;PSMB4;PSMB5;PSMB6;PSMB7 common genes common pathways GO:0010243| response to organic nitrogen PSMB2;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway PSMA3;TNFSF11;PSMA6;PSMA4;PSMB5;PSMA7;PSMA1;PSMA2;PSMB6;PSMB2;PSMB4;PSMB3;PSMB1;PSMA5;PSMB7 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;PSMB4;PSMB2;PSMB6;PSMA2;PSMA7;PSMA1;PSMB7;PSMB3;PSMB1;PSMA5;PSMA3;PSMB5;PSMA4;PSMA6 GO:0006979| response to oxidative stress PSMB5;PTGS2 GO:0055085| transmembrane transport PSMB7;PSMA5;PSMB1;PSMB3;PSMB4;PSMB2;PSMA1;PSMA7;PSMA2;PSMB6;PSMA4;PSMB5;PSMA6;ABCB1;PSMA3 GO:0050727| regulation of inflammatory response PTGS2;PSMA6 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;PSMA6 GO:0014070| response to organic cyclic compound PSMB2;PTGS2 37542:[DB00480 DB06446] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0055085| transmembrane transport CACNA1A;ABCB1 GO:0007568| aging HTR2A;PTGS2 GO:0042493| response to drug ABCB1;HTR2C;PTGS2;HTR2A GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0019233| sensory perception of pain PTGS2;HTR2A 37543:[DB00480 DB01403] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;DRD2;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1A;ADRA1D;CHRM3 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B;ADRA1A;HTR2A;ADRA1D;ADRA2C;HRH1 GO:0007613| memory DRD1;HTR2A;PTGS2;HRH1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP2D6 GO:0042493| response to drug PTGS2;DRD2;ADRA1A;HTR2A;CYP2E1;DRD1;DRD3;ABCB1;HTR2C GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2;ADRA2A;ADRA1D;DRD3;CHRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0007612| learning DRD3;DRD5;DRD1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007568| aging PTGS2;HTR2A;ADRA1A 37544:[DB00480 DB04648] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04648|S-propylamine-L-cysteine ARG1 common genes common pathways GO:0010042| response to manganese ion PTGS2;ARG1 GO:0042493| response to drug ARG1;PTGS2;ABCB1 GO:0032496| response to lipopolysaccharide ARG1;PTGS2 GO:0007568| aging ARG1;PTGS2 37545:[DB00480 DB03306] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03306|RU78300 SRC common genes common pathways GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:1902533| SRC;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| SRC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug ABCB1;PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;SRC 37546:[DB00480 DB14009] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes PTGS2 common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;TNFSF11 GO:0006954| inflammatory response PTGS2;IDO1;PTGS1;ALOX5;CNR2;TRPV1;ALOX15 GO:0010942| positive regulation of cell death PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0006955| immune response TNFSF11;OPRD1;CNR2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;PPARG;CNR1;IDO1;SMPD1;PTGS2;TRPV1;SOD1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation CAT;OPRM1;PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:1990776| PTGS2 GO:0001503| ossification ALOX15;TNFSF11 GO:0006629| lipid metabolic process CYP1A2;CYP2D6;ALOX15;CYP2C9;GPX1;CYP3A4;PLA2G1B;PPARG;PTGS1;DAGLA;TRPV1;NAAA;NAPEPLD;HMGCR;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain TRPV1;HTR2A;CNR2;OPRD1;PTGS2;TRPA1;CNR1;OPRM1 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation CYP1B1;PPARG;OPRM1;CDH5;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1;SOD1;PPARG GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PPARG;TRPA1;CYP1A1;ACAT1;PTGS2;AANAT GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0045453| bone resorption TNFSF11;GPR55 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0006633| fatty acid biosynthetic process PLA2G1B;PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0010226| response to lithium ion PTGS2 GO:0047484| regulation of response to osmotic stress TRPV4;ABCB1 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory CNR1;HTR2A;PTGS2;CHRNA7 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;CNR2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;GPX1 GO:0009750| response to fructose stimulus PTGS2 GO:0042493| response to drug PTGS2;ABCG2;SMPD1;ABCC1;SOD1;HTR2A;CYP1A1;ABCB1;PPARG;TRPA1;CAT;CYP1A2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2;ALOX15 GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP2C19;IDO1;PTGS1;ALOX5;SOD1;CYP3A7;CYP17A1;CYP3A5;CYP1A1;GPX1;CYP3A4;GSR;CYP1B1;CAT;CYP1A2;CYP2D6;ALOX15;CRYZ;CYP2C9 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;TNFSF11 GO:0008284| positive regulation of cell proliferation CHRNA7;HMGCR;PTGS2;HTR1A;HTR2A GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR;SOD1;GPX1;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0007155| cell adhesion CDH5;CYP1B1 GO:0007612| learning PTGS2;VDAC1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;CNR1;OPRM1;CYP1A1;CNR2;IDO1;PTGS2 GO:0071318| cellular response to ATP PTGS2;TRPV1;SOD1 GO:0046330| positive regulation of JNK cascade TNFSF11;TRPV4 GO:0071284| cellular response to lead ion PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0010033| response to organic substance CYP1A1;SOD1;PTGS2;CYP1A2;TRPA1;PPARG GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport ABCC1;TRPM8;ABCG2;TRPV4;TRPV3;CACNA1H;TRPV2;TRPV1;TRPA1;ABCB1;CACNA1G;CACNA1I;VDAC1 GO:0007043| cell-cell junction assembly TRPV4;CDH5 GO:0051260| protein homooligomerization ACAT1;TNFSF11;GLRA3;GLRA1 GO:0006979| response to oxidative stress GPX1;CAT;PTGS2;SOD1;PTGS1 GO:0098869| PTGS2;PTGS1;GSR;GPX1;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TRPV1;OPRM1 GO:0032355| response to estradiol stimulus CAT;CYP1A2;PTGS2 GO:1902219| PTGS2 GO:0034605| cellular response to heat TRPV1;PTGS2;TRPV4 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;SLC29A1 GO:0097756| HMGCR;PTGS2 GO:0007568| aging HMGCR;PTGS2;NAPEPLD;CYP1A1;HTR2A;SOD1;CNR1;CAT GO:0030282| bone mineralization PTGS2;ALOX15 GO:0006810| transport ABCG2;ABCC1;TRPV2;TRPV1;ABCB1;CACNA1I GO:0046697| decidualization PTGS2 37547:[DB00480 DB00137] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00137|Lutein ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS2 37548:[DB00480 DB08954] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0007612| learning GRIN1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 GO:0006810| transport GRIN2B;ABCB1 GO:0019233| sensory perception of pain PTGS2;GRIN1 GO:0043065| positive regulation of apoptotic process PTGS2;GRIN1 GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0019722| calcium-mediated signaling GRIN2B;TNFSF11;GRIN1 GO:0007613| memory GRIN1;PTGS2 37549:[DB00480 DB01345] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01345|Potassium cation ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0008217| regulation of blood pressure PTGS2;ATP1A1 GO:0042493| response to drug ABCB1;ATP1A1;PTGS2 37550:[DB00480 DB00505] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 37551:[DB00480 DB08490] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08490|CTS-1027 MMP13 common genes common pathways GO:0030282| bone mineralization MMP13;PTGS2 37552:[DB00480 DB08775] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08775|Nα-[(Benzyloxy)carbonyl]-N-[(2S)-4-fluoro-3-oxo-2-butanyl]-L-tyrosinamide CTSF common genes common pathways 37553:[DB00480 DB09499] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09499|Thiosulfuric acid TST common genes common pathways 37554:[DB00480 DB00166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways GO:0006810| transport ABCB1;SLC5A6 GO:0006979| response to oxidative stress LIAS;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC5A6 GO:0032496| response to lipopolysaccharide LIAS;PTGS2 GO:0043066| negative regulation of apoptotic process POR;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;POR GO:0055114| oxidation-reduction process PTGS2;POR GO:0006629| lipid metabolic process PTGS2;LIPT1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;POR GO:0006954| inflammatory response LIAS;PTGS2 37555:[DB00480 DB04149] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04149|(R)-Rolipram PDE4B;PDE4D common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PDE4D GO:0007568| aging PDE4D;PTGS2 37556:[DB00480 DB11635] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes ABCB1 common pathways GO:0006810| transport TTPA;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG8;ABCB1;ABCA1;ABCG5 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP4F2;PTGS2;CYP3A4 GO:0099040| ABCB1 GO:0042493| response to drug ABCG5;NPC1L1;PTGS2;ABCB1;ABCA1;ABCG8 GO:0042908| xenobiotic transport ABCB1 GO:0045332| phospholipid translocation ABCA1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0008217| regulation of blood pressure CYP4F2;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCG5 GO:0006629| lipid metabolic process NPC1L1;PTGS2;APOBR;TTPA;CYP3A4;ABCA1 37557:[DB00480 DB08370] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08370|S-(4-BROMOBENZYL)CYSTEINE GSTP1 common genes common pathways GO:0098869| GSTP1;PTGS2 GO:0032355| response to estradiol stimulus GSTP1;PTGS2 GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2 37558:[DB00480 DB00837] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0006810| transport ABCB1;GABRA1 37559:[DB00480 DB06785] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06785|Ganirelix GNRHR common genes common pathways GO:0007275| multicellular organismal development GNRHR;TNFSF11 37560:[DB00480 DB11235] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11235|Thonzylamine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0006954| inflammatory response PTGS2;HRH1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory PTGS2;HRH1 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 37561:[DB00480 DB13620] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;ATP4B GO:0042493| response to drug ATP1A1;PTGS2;ABCB1 GO:0007155| cell adhesion CDH5;ATP4B GO:0032496| response to lipopolysaccharide PTGS2;ATP4B GO:0042127| regulation of cell proliferation FXYD2;PTGS2 GO:0055085| transmembrane transport SLC12A1;ABCB1 GO:0006810| transport ABCB1;FXYD2;ATP4A;SLC12A1 37562:[DB00480 DB01191] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01191|Dexfenfluramine SLC6A4;HTR2C;CYP2D6;CYP1A2;CYP2E1 common genes common pathways GO:0007613| memory SLC6A4;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2;SLC6A4 GO:0010033| response to organic substance CYP1A2;SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP2D6;CYP1A2 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1;SLC6A4;HTR2C;CYP1A2 37563:[DB00480 DB05137] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05137|Lobeline CHRNA9;CHRNA10;CHRNA7 common genes common pathways GO:0007613| memory CHRNA7;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0042127| regulation of cell proliferation CHRNA10;PTGS2 37564:[DB00480 DB03496] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03496|Alvocidib CDK2;CDK5;CDK9;CDK1;CDK6;EGFR;CDK4;CDK8;CDK7;PYGM;PYGB;PYGL;UGT1A1;ABCG2 common genes common pathways GO:0042127| regulation of cell proliferation CDK4;PTGS2;CDK6;EGFR GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;CDK7;CDK9;EGFR;CDK8 GO:0008284| positive regulation of cell proliferation CDK4;PTGS2;CDK2;EGFR GO:0045786| negative regulation of cell cycle PTGS2;CDK6;CDK5 GO:0043066| negative regulation of apoptotic process EGFR;PTGS2;CDK1 GO:0042493| response to drug UGT1A1;ABCG2;CDK4;PTGS2;CDK1;ABCB1;CDK9 GO:0010243| response to organic nitrogen CDK1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0032355| response to estradiol stimulus PTGS2;EGFR GO:0098609| EGFR;CDH5 GO:0006810| transport ABCG2;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0006979| response to oxidative stress PTGS2;EGFR GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;CDK1 GO:0000086| G2/M transition of mitotic cell cycle CDK2;CDK1;CDK7;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0043406| positive regulation of MAP kinase activity EGFR;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0010033| response to organic substance UGT1A1;CDK2;CDK4;PTGS2 GO:0007275| multicellular organismal development CDK2;CDK4;EGFR;TNFSF11 GO:0019233| sensory perception of pain PTGS2;CDK5 GO:0043065| positive regulation of apoptotic process CDK4;PTGS2 GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0001503| ossification TNFSF11;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0030154| cell differentiation TNFSF11;CDK6 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0014070| response to organic cyclic compound CDK1;EGFR;UGT1A1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;CDK6 37565:[DB00480 DB04459] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04459|3,4-Dichloroisocoumarin CFD common genes common pathways 37566:[DB00480 DB07101] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07101|PD-0325901 MAP2K1 common genes common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAP2K1 GO:0008285| negative regulation of cell proliferation PTGS2;MAP2K1;CDH5 37567:[DB00480 DB04754] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04754|GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006955| immune response PNP;TNFSF11 37568:[DB00480 DB03695] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03695|Piritrexim DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 37569:[DB00480 DB01979] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01979|Methyl alpha-D-mannoside MBL2 common genes common pathways GO:0006979| response to oxidative stress MBL2;PTGS2 37570:[DB00480 DB02845] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02845|Methylphosphinic Acid BCHE;ACHE;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0007612| learning PTGS2;BCHE GO:0007155| cell adhesion CDH5;ACHE GO:0042493| response to drug ABCB1;BCHE;PTGS2 37571:[DB00480 DB01173] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0019233| sensory perception of pain PTGS2;SCN10A;GRIN1 GO:0043065| positive regulation of apoptotic process PTGS2;GRIN1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP3A4 GO:0055074| calcium ion homeostasis GRIN1;TNFSF11 GO:0006954| inflammatory response PTGS2;HRH1 GO:0019722| calcium-mediated signaling TNFSF11;GRIN2D;GRIN1 GO:0007613| memory HRH1;PTGS2;GRIN1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0007612| learning PTGS2;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;GRIN1 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;SLC6A2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP3A4;CYP2B6;CYP1A2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A2;SCN10A GO:0010033| response to organic substance PTGS2;CYP1A2 37572:[DB00480 DB02877] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02877|Arotinoid acid RARB common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RARB GO:0043066| negative regulation of apoptotic process PTGS2;RARB GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;RARB GO:0043065| positive regulation of apoptotic process RARB;PTGS2 37573:[DB00480 DB08454] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08454|N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE CAMK1D common genes common pathways GO:0043066| negative regulation of apoptotic process CAMK1D;PTGS2 GO:0006954| inflammatory response PTGS2;CAMK1D GO:0043065| positive regulation of apoptotic process CAMK1D;PTGS2 37574:[DB00480 DB07469] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07469|(3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 37575:[DB00480 DB06706] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0007568| aging PTGS2;ADRA1A GO:0055085| transmembrane transport ABCB1;SLC18A2 GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;PTGS2 37576:[DB00480 DB00238] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2;CYP2C9;CYP2D6 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0098869| PTGS2;ALB GO:0055085| transmembrane transport ABCB1;SLC22A1 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process CYP3A5;PTGS2;CYP1A2;CYP2D6;CYP2C9;CYP2B6;CYP3A4;CYP2A6 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 37577:[DB00480 DB02373] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02373|Adenosine Monotungstate FHIT common genes common pathways 37578:[DB00480 DB11792] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A43;CYP3A4;CYP3A7;CYP3A5;PTGS2 37579:[DB00480 DB03856] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03856|L-Eflornithine ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;ODC1 37580:[DB00480 DB01120] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;VEGFA GO:0055085| transmembrane transport ABCB1;ABCC8 GO:0098869| ALB;PTGS2 GO:0010469| regulation of receptor activity VEGFA;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0042493| response to drug PTGS2;ABCC8;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;PTGS2;VEGFA GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VEGFA GO:0060749| mammary gland alveolus development VEGFA;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;ABCC8 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA GO:0030154| cell differentiation VEGFA;TNFSF11 GO:0007613| memory ABCC8;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0042327| positive regulation of phosphorylation VEGFA;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0007275| multicellular organismal development TNFSF11;VEGFA GO:0001525| angiogenesis PTGS2;VEGFA 37581:[DB00480 DB07339] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways GO:0055114| oxidation-reduction process NQO2;PTGS2 37582:[DB00480 DB06471] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06471|Naxifylline ADORA1 common genes common pathways GO:0006954| inflammatory response PTGS2;ADORA1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;ADORA1 GO:0043066| negative regulation of apoptotic process ADORA1;PTGS2 GO:0050728| negative regulation of inflammatory response ADORA1;CDH5 GO:0097756| PTGS2;ADORA1 37583:[DB00480 DB00423] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00423|Methocarbamol CA1 common genes common pathways 37584:[DB00480 DB02776] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02776|1-Hexadecanosulfonic Acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0050873| brown fat cell differentiation PTGS2;FABP4 37585:[DB00480 DB06726] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0045453| bone resorption ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2;ADRB3 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0007568| aging PTGS2;ADRB3 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 37586:[DB00480 DB01933] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01933|7-Hydroxystaurosporine PDPK1 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;PDPK1 37587:[DB00480 DB08365] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08365|8-bromo-4-(2-chlorophenyl)-N-(2-hydroxyethyl)-6-methyl-1,3-dioxo-1,2,3,6-tetrahydropyrrolo[3,4-e]indole-7-carboxamide WEE1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle WEE1;ABCB1 37588:[DB00480 DB03606] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03606|(S)-Rolipram PDE4D;PDE4B common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity TNFSF11;PDE4D 37589:[DB00480 DB07217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07217|N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-fluorobenzamide MAPK10 common genes common pathways 37590:[DB00480 DB11477] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA2C 37591:[DB00480 DB03977] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03977|N-Trimethyllysine CYCS;CALM1 common genes common pathways GO:0055085| transmembrane transport CALM1;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYCS 37592:[DB00480 DB11274] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042493| response to drug PTGS2;DRD1;DRD2;DRD3;ABCB1 GO:0007612| learning PTGS2;DRD1;DRD3;DRD5 GO:0008284| positive regulation of cell proliferation PTGS2;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0007613| memory DRD1;PTGS2 37593:[DB00480 DB00070] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00070|Hyaluronidase TGFB1;ALB common genes common pathways GO:0033280| response to vitamin D TGFB1;PTGS2 GO:0014070| response to organic cyclic compound TGFB1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;TGFB1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TGFB1 GO:0006954| inflammatory response PTGS2;TGFB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TGFB1;TNFSF11 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;TGFB1 GO:0071260| cellular response to mechanical stimulus TGFB1;PTGS2 GO:0009314| response to radiation PTGS2;TGFB1 GO:0042307| positive regulation of protein import into nucleus TGFB1;PTGS2 GO:0043065| positive regulation of apoptotic process TGFB1;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;TGFB1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;TGFB1 GO:0010033| response to organic substance TGFB1;PTGS2 GO:0007568| aging PTGS2;TGFB1 GO:0010469| regulation of receptor activity TNFSF11;TGFB1 GO:0032355| response to estradiol stimulus PTGS2;TGFB1 GO:0098869| PTGS2;ALB GO:0042493| response to drug ABCB1;TGFB1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TGFB1;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;TGFB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TGFB1 GO:0008284| positive regulation of cell proliferation PTGS2;TGFB1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0045786| negative regulation of cell cycle TGFB1;PTGS2 37594:[DB00480 DB01352] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0007613| memory PTGS2;CHRNA7 GO:0019233| sensory perception of pain CHRNA4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport ABCB1;GABRA1;GRIK2;GABRA6;GABRA4;GABRA3;GABRA5 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 37595:[DB00480 DB02255] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02255|GM6001 ADAM28;ACAN common genes common pathways GO:0007155| cell adhesion CDH5;ACAN 37596:[DB00480 DB06468] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0030154| cell differentiation SLC9A1;TNFSF11 GO:0014070| response to organic cyclic compound PTGS2;SLC9A1 GO:0043065| positive regulation of apoptotic process SLC9A1;PTGS2 GO:0071260| cellular response to mechanical stimulus SLC9A1;PTGS2 GO:0006979| response to oxidative stress PTGS2;MPO GO:1902533| SLC9A1;TNFSF11 GO:0071456| cellular response to hypoxia SLC9A1;PTGS2 GO:0007568| aging PTGS2;MPO GO:0055085| transmembrane transport SLC9A1;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;SLC9A1 GO:0043066| negative regulation of apoptotic process SLC9A1;MPO;PTGS2 GO:0032496| response to lipopolysaccharide MPO;PTGS2 GO:0055114| oxidation-reduction process MPO;PTGS2 37597:[DB00480 DB07638] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07638|(3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR1;ESR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;ESR2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 37598:[DB00480 DB06833] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06833|1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE ESRRA common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;ESRRA GO:0045670| regulation of osteoclast differentiation ESRRA;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESRRA GO:0042127| regulation of cell proliferation ESRRA;PTGS2 37599:[DB00480 DB13932] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13932|Voretigene Neparvovec RPE65 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;RPE65 37600:[DB00480 DB07967] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07967|9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 37601:[DB00480 DB06358] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06358|Iclaprim DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 37602:[DB00480 DB14185] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2;CYP3A7;CYP3A5 GO:0042493| response to drug PTGS2;ADRA1A;DRD2;HTR2A;DRD1;DRD3;HTR1B;ABCB1;HTR2C GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0007612| learning DRD1;PTGS2;DRD5;DRD3 GO:0008284| positive regulation of cell proliferation ADRA2A;DRD3;CHRM1;HTR2A;PTGS2;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD3;DRD2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0098869| ALB;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0007275| multicellular organismal development ADRA1B;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction CHRM3;ADRA1A;PTGS2;ADRA1B GO:0007613| memory PTGS2;HTR2A;DRD1;HRH1 GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;ADRA1A;HTR2A;HRH1;ADRA2C 37603:[DB00480 DB02306] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02306|Palmitoyl-Linoleoyl Phosphatidylcholine PCTP common genes common pathways 37604:[DB00480 DB08089] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08089|LGD-2226 AR common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0006810| transport AR;ABCB1 37605:[DB00480 DB01044] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0098869| PTGS2;ALB GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 37606:[DB00480 DB04012] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04012|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Leucine FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A 37607:[DB00480 DB02557] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02557|Phosphoramidon MME;KEL common genes common pathways GO:0019233| sensory perception of pain PTGS2;MME 37608:[DB00480 DB04281] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04281|2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone DHODH common genes common pathways GO:0042493| response to drug DHODH;PTGS2;ABCB1 GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 37609:[DB00480 DB05171] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05171|E-2012 APH1A;PSENEN common genes common pathways GO:0043065| positive regulation of apoptotic process PSENEN;APH1A;PTGS2 37610:[DB00480 DB03332] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03332|5,6-Cyclic-Tetrahydropteridine NOS3 common genes common pathways GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process PTGS2;NOS3 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;NOS3;CDH5 GO:0001525| angiogenesis NOS3;PTGS2 37611:[DB00480 DB04894] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0019233| sensory perception of pain TACR1;PTGS2 GO:0006954| inflammatory response TACR1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;TACR1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TACR1 GO:0008285| negative regulation of cell proliferation PTGS2;SSTR2;SSTR5;CDH5 GO:0008217| regulation of blood pressure PTGS2;TACR1 GO:0014070| response to organic cyclic compound TACR1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0032355| response to estradiol stimulus PTGS2;TACR1 37612:[DB00480 DB00772] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00772|Malathion BCHE;CYP1A2;CYP2B6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;BCHE;CYP1A2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP2B6 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 37613:[DB00480 DB03760] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03760|Dihydrolipoic Acid GCSH;DLAT;PDK3 common genes common pathways 37614:[DB00480 DB07135] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07135|(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion DPP4;CDH5 37615:[DB00480 DB09079] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09079|Nintedanib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FLT3;LCK;LYN;SRC;CYP3A4;ABCB1 common genes ABCB1 common pathways GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0050870| positive regulation of T cell activation TNFSF11;LCK GO:0070542| response to fatty acid PTGS2;SRC GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0030154| cell differentiation TNFSF11;FLT3;FLT1;KDR GO:0042908| xenobiotic transport ABCB1 GO:0008285| negative regulation of cell proliferation LYN;CDH5;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0006855| drug transmembrane transport ABCB1 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0050727| regulation of inflammatory response LYN;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;LYN GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4 GO:0001525| angiogenesis FGFR2;FLT1;FLT4;KDR;FGFR1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;FLT1;KDR GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0006954| inflammatory response PTGS2;LYN GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:1902533| TNFSF11;SRC GO:0098609| CDH5;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0006810| transport ABCB1 GO:0030282| bone mineralization PTGS2;FGFR2;FGFR3 GO:0009887| organ morphogenesis TNFSF11;FGFR2 GO:0043406| positive regulation of MAP kinase activity SRC;FLT1;FGFR1;TNFSF11;FLT3 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0008284| positive regulation of cell proliferation FGFR2;FLT3;FGFR3;LYN;PTGS2;FGFR1;KDR;FLT4;FLT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;FLT4;KDR;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0042127| regulation of cell proliferation LCK;PTGS2;FGFR1;SRC GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;FGFR2 GO:0046330| positive regulation of JNK cascade FLT4;TNFSF11 GO:0010243| response to organic nitrogen PTGS2;FLT3 GO:0048661| positive regulation of smooth muscle cell proliferation FGFR2;PTGS2 GO:0019221| cytokine-mediated signaling pathway FLT3;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGFR3;FGFR2;SRC;FGFR1;LCK GO:0042493| response to drug SRC;LCK;PTGS2;LYN;ABCB1 GO:0002548| monocyte chemotaxis TNFSF11;FLT1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0034332| adherens junction organization SRC;CDH5 GO:0099040| ABCB1 37616:[DB00480 DB07525] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;FGFR1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGFR1 GO:0042127| regulation of cell proliferation PTGS2;FGFR1 GO:0008284| positive regulation of cell proliferation PTGS2;FGFR1 GO:0001525| angiogenesis FGFR1;PTGS2 37617:[DB00480 DB06993] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06993|(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion CDH5;DPP4 37618:[DB00480 DB05667] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05667|Levoketoconazole CYP11B1;CYP51A1 common genes common pathways GO:0006629| lipid metabolic process CYP51A1;PTGS2;CYP11B1 GO:0006955| immune response CYP11B1;TNFSF11 GO:0008217| regulation of blood pressure CYP11B1;PTGS2 GO:0055114| oxidation-reduction process CYP51A1;PTGS2;CYP11B1 37619:[DB00480 DB06184] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06184|AEG35156 XIAP common genes common pathways GO:0050727| regulation of inflammatory response XIAP;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;XIAP GO:0042127| regulation of cell proliferation XIAP;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;XIAP GO:0016567| protein ubiquitination CRBN;XIAP 37620:[DB00480 DB08953] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08953|Indalpine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37621:[DB00480 DB02919] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02919|2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 37622:[DB00480 DB01131] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9;CYP2D6 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2D6;PTGS2;DHFR;CYP2C19;CYP2E1 GO:0042493| response to drug CYP2E1;PTGS2;ABCB1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 37623:[DB00480 DB07141] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07141|5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 37624:[DB00480 DB05078] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05078|AER001 IL4R;IL13RA2 common genes common pathways GO:0030728| ovulation IL4R;PTGS2 GO:0006955| immune response IL4R;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;IL4R GO:0019221| cytokine-mediated signaling pathway IL4R;TNFSF11;IL13RA2 37625:[DB00480 DB00572] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0007612| learning CHRNB2;PTGS2 GO:0051260| protein homooligomerization GLRA1;TNFSF11 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0006810| transport ABCB11;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0019233| sensory perception of pain CHRNA4;PTGS2;CHRNB2 GO:0007613| memory CHRNB2;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 37626:[DB00480 DB05332] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05332|Romiplostim MPL common genes common pathways GO:0019221| cytokine-mediated signaling pathway MPL;TNFSF11 37627:[DB00480 DB05339] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05339|MN-305 HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 37628:[DB00480 DB07036] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07036|(3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2 37629:[DB00480 DB00110] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0010469| regulation of receptor activity FCGR2B;TNFSF11 GO:0046330| positive regulation of JNK cascade TNFSF11;FCGR2B GO:0006954| inflammatory response FCGR2B;PTGS2 GO:0006955| immune response C1R;FCGR3B;FCGR1A;TNFSF11;FCGR3A;C1QC;FCGR2B;FCGR2C 37630:[DB00480 DB03084] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03084|Cyclopropyl-{4-[5-(3,4-Dichlorophenyl)-2-[(1-Methyl)-Piperidin]-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine MAPK10 common genes common pathways 37631:[DB00480 DB01094] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;MTTP;PTGS2;SOAT1;SOAT2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;ABCG2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0006810| transport ABCG2;ABCB1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 37632:[DB00480 DB05139] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05139|CR002 PDGFD common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PDGFD GO:0008284| positive regulation of cell proliferation PDGFD;PTGS2 GO:0043406| positive regulation of MAP kinase activity PDGFD;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;PDGFD GO:0007275| multicellular organismal development TNFSF11;PDGFD 37633:[DB00480 DB11275] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0007613| memory PTGS2;DRD1 GO:0042493| response to drug PTGS2;DRD1;DRD2;ABCB1;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;PTGS2 GO:0007612| learning PTGS2;DRD1;DRD3;DRD5 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 37634:[DB00480 DB00650] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 37635:[DB00480 DB08980] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08980|Fendiline CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37636:[DB00480 DB09026] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09026|Aliskiren REN;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0008217| regulation of blood pressure PTGS2;REN GO:0032496| response to lipopolysaccharide PTGS2;REN GO:0042493| response to drug ABCB1;REN;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0010033| response to organic substance REN;PTGS2 37637:[DB00480 DB07028] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07028|(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0010033| response to organic substance AKR1B1;PTGS2 37638:[DB00480 DB04738] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04738|Motuporin PPP1CC common genes common pathways 37639:[DB00480 DB01247] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01247|Isocarboxazid MAOA;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0042493| response to drug PTGS2;MAOB;ABCB1 GO:0055114| oxidation-reduction process MAOA;PTGS2;MAOB 37640:[DB00480 DB09183] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCG2;ABCB5;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0030154| cell differentiation ABCB5;TNFSF11 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCB5 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB5;ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0042493| response to drug ABCB1;PTGS2;ABCG2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2;CYP2C8 GO:0099040| ABCB1 GO:1901529| ABCB1 37641:[DB00480 DB08449] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08449|2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid AKR1B1 common genes common pathways GO:0010033| response to organic substance PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 37642:[DB00480 DB07542] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07542|5-AMINO-6-CYCLOHEXYL-4-HYDROXY-2-ISOBUTYL-HEXANOIC ACID CTSD common genes common pathways 37643:[DB00480 DB05001] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05001|PSN9301 DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion CDH5;DPP4 37644:[DB00480 DB11973] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11973|Tesevatinib EGF;EPHB4;ERBB2 common genes common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;EGF GO:0042327| positive regulation of phosphorylation TNFSF11;EGF GO:0001525| angiogenesis EPHB4;PTGS2;EGF GO:0007275| multicellular organismal development TNFSF11;EPHB4 GO:0043406| positive regulation of MAP kinase activity EGF;ERBB2;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGF;ERBB2 GO:0060749| mammary gland alveolus development EGF;TNFSF11 GO:0007155| cell adhesion CDH5;EPHB4 GO:0008284| positive regulation of cell proliferation EGF;PTGS2 37645:[DB00480 DB06857] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06857|N-(4-CARBAMIMIDOYL-3-CHORO-PHENYL)-2-HYDROXY-3-IODO-5-METHYL-BENZAMIDE PLAU common genes common pathways GO:0042127| regulation of cell proliferation PLAU;PTGS2 GO:0010469| regulation of receptor activity PLAU;TNFSF11 37646:[DB00480 DB13933] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0032355| response to estradiol stimulus F7;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade F7;TNFSF11;F10 GO:0055114| oxidation-reduction process PTGS2;F8 GO:0014070| response to organic cyclic compound F7;PTGS2 37647:[DB00480 DB04796] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04796|Inecalcitol VDR common genes common pathways GO:0046697| decidualization VDR;PTGS2 GO:0009887| organ morphogenesis VDR;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;VDR GO:0007275| multicellular organismal development VDR;TNFSF11 37648:[DB00480 DB02930] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02930|Adenosine 5'-[γ-thio]triphosphate BST1;SYN1;BCKDK;PFKFB1;PMS2;recA;recA;recA;recQ common genes common pathways GO:0042493| response to drug ABCB1;PMS2;PTGS2 GO:0008284| positive regulation of cell proliferation BST1;PTGS2 GO:0050727| regulation of inflammatory response BST1;PTGS2 GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 37649:[DB00480 DB13948] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0007613| memory PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0007568| aging PTGS2;HTR2A GO:0042493| response to drug ABCB1;PTGS2;HTR2A GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2 37650:[DB00480 DB08574] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08574|(5R)-2-SULFANYL-5-[4-(TRIFLUOROMETHYL)BENZYL]-1,3-THIAZOL-4-ONE MLLT4 common genes common pathways 37651:[DB00480 DB01466] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2D6;POR;CYP3A4;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;POR GO:0043066| negative regulation of apoptotic process POR;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;POR GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0009314| response to radiation OPRM1;PTGS2 GO:0019233| sensory perception of pain OPRM1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 37652:[DB00480 DB00568] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2D6;CYP2C9;CYP3A4 GO:0006954| inflammatory response HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;DRD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2;CYP1A2 GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2;CYP1A2 GO:0007612| learning DRD1;PTGS2;DRD5 GO:0055114| oxidation-reduction process CYP1A1;PTGS2;CYP2B6;CYP2C9;CYP2D6;CYP1A2;CYP2A6;CYP3A4 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;DRD1;DRD2;CYP1A1 GO:0006810| transport ABCB1;CACNA1I GO:0007568| aging CYP1A1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0010033| response to organic substance CYP1A2;CYP1A1;PTGS2 GO:0055085| transmembrane transport ABCB1;CACNA1F;CACNA1I;CACNA1G;CACNA1S;CACNA1H;CACNA1D;CACNA1C 37653:[DB00480 DB07768] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0006693| prostaglandin metabolic process AKR1C2;PTGS2 GO:0006629| lipid metabolic process AKR1C2;PTGS2 GO:0051260| protein homooligomerization AKR1C1;TNFSF11 GO:0055114| oxidation-reduction process AKR1C2;AKR1C1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;AKR1C2 GO:0008284| positive regulation of cell proliferation AKR1C2;PTGS2 37654:[DB00480 DB05482] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05482|7-ethyl-10-hydroxycamptothecin TOP1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;TOP1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 37655:[DB00480 DB01053] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0055085| transmembrane transport SLC15A1;SLC22A4;ABCB1;SLCO4A1;SLCO1B1;SLC22A5;SLC15A2;SLC22A8;SLCO2B1;SLC22A6;SLC22A11;SLCO3A1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 37656:[DB00480 DB00350] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00350|Minoxidil KCNJ1;PTGS1;REN;UGT1A1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide REN;UGT1A1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;PTGS1 GO:0042493| response to drug REN;ABCB1;UGT1A1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0010033| response to organic substance REN;PTGS2;UGT1A1 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1;REN 37657:[DB00480 DB06830] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06830|(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 37658:[DB00480 DB03247] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03247|Flavin mononucleotide RPS6KA4;HAO2;POR;PPCDC;pdxH;aroC;BLVRB;HAO1;PNPO;RFK;NOS1;pyrD;DPYD;DHODH;azoR;azoR;aroC;SGK1;POR common genes common pathways GO:0006979| response to oxidative stress PTGS2;HAO1 GO:0042127| regulation of cell proliferation PTGS2;SGK1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RPS6KA4;NOS1 GO:0043066| negative regulation of apoptotic process POR;PTGS2 GO:0055114| oxidation-reduction process NOS1;BLVRB;DPYD;POR;PNPO;PTGS2;HAO2;DHODH;HAO1 GO:0042493| response to drug PTGS2;DHODH;ABCB1;POR GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0014070| response to organic cyclic compound DHODH;PTGS2 GO:0008217| regulation of blood pressure PTGS2;SGK1 GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process POR;PTGS2 GO:0006954| inflammatory response RPS6KA4;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;RPS6KA4 37659:[DB00480 DB03907] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0042493| response to drug COMT;ABCB1;PTGS2 GO:0007612| learning PTGS2;COMT GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0014070| response to organic cyclic compound COMT;PTGS2 37660:[DB00480 DB01085] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP3A4;CYP2A6 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 37661:[DB00480 DB06354] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06354|Tezampanel GRIK1;GABBR1 common genes common pathways GO:0006810| transport ABCB1;GRIK1 GO:0055085| transmembrane transport ABCB1;GRIK1 37662:[DB00480 DB12773] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12773|Sifalimumab IFNA2 common genes common pathways GO:0006954| inflammatory response IFNA2;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;IFNA2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IFNA2 GO:0010469| regulation of receptor activity TNFSF11;IFNA2 37663:[DB00480 DB04893] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04893|AZD3409 FNTB;FNTA common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;FNTB GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CDH5 37664:[DB00480 DB07068] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07068|(4-{4-[(TERT-BUTOXYCARBONYL)AMINO]-2,2-BIS(ETHOXYCARBONYL)BUTYL}PHENYL)SULFAMIC ACID PTPRB common genes common pathways GO:0001525| angiogenesis PTGS2;PTPRB 37665:[DB00480 DB04521] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04521|GSHNA GSTA3 common genes common pathways 37666:[DB00480 DB04756] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04756|2-[(3,5-Dichloro-4-trioxidanylphenyl)amino]benzoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TTR;TNFSF11 37667:[DB00480 DB02018] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02018|Amido Phenyl Pyruvic Acid TPSB2 common genes common pathways 37668:[DB00480 DB11731] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11731|Depatuxizumab mafodotin EGFR;TUBB common genes common pathways GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification TNFSF11;EGFR GO:0007275| multicellular organismal development TNFSF11;EGFR GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0014070| response to organic cyclic compound PTGS2;EGFR GO:0043066| negative regulation of apoptotic process EGFR;PTGS2 GO:0008284| positive regulation of cell proliferation EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0006979| response to oxidative stress PTGS2;EGFR GO:0098609| CDH5;EGFR GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0032355| response to estradiol stimulus PTGS2;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 37669:[DB00480 DB04753] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04753|9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006955| immune response PNP;TNFSF11 GO:0042493| response to drug PNP;ABCB1;PTGS2 37670:[DB00480 DB00883] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 GO:0008217| regulation of blood pressure NPR1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37671:[DB00480 DB02264] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02264|O2-Sulfo-Glucuronic Acid FGF1;HGF;HS3ST3A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;HGF GO:0007275| multicellular organismal development TNFSF11;FGF1 GO:0001525| angiogenesis FGF1;PTGS2 GO:0030154| cell differentiation TNFSF11;FGF1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGF1;HGF GO:0050728| negative regulation of inflammatory response CDH5;HGF GO:0043066| negative regulation of apoptotic process HGF;PTGS2 GO:0008284| positive regulation of cell proliferation HGF;PTGS2;FGF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;TNFSF11;HGF GO:0043406| positive regulation of MAP kinase activity TNFSF11;FGF1 GO:0034605| cellular response to heat FGF1;PTGS2 GO:0010469| regulation of receptor activity FGF1;TNFSF11;HGF GO:1902533| TNFSF11;FGF1 37672:[DB00480 DB05883] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05883|ABX-PTH PTH common genes common pathways GO:0045453| bone resorption TNFSF11;PTH GO:0033280| response to vitamin D PTH;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PTH;TNFSF11 GO:0042493| response to drug PTGS2;ABCB1;PTH GO:0010469| regulation of receptor activity PTH;TNFSF11 37673:[DB00480 DB08841] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08841|Tyramine SLC22A3 common genes common pathways GO:0006855| drug transmembrane transport SLC22A3;ABCB1 GO:0055085| transmembrane transport SLC22A3;ABCB1 37674:[DB00480 DB07443] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07443|(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0014070| response to organic cyclic compound DHODH;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0042493| response to drug DHODH;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;DHODH 37675:[DB00480 DB11619] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0006810| transport ABCB1;AR GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0060749| mammary gland alveolus development TNFSF11;ESR1;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;NR3C1;TNFSF11;ESR1 GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0038001| paracrine signaling TNFSF11;PGR GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0007275| multicellular organismal development GNRHR;TNFSF11 37676:[DB00480 DB07032] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07032|2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TNFSF11 37677:[DB00480 DB09272] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;ABCC2 GO:0032496| response to lipopolysaccharide OPRM1;ABCC2;PTGS2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLC22A8;SLCO1B1 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0006810| transport ABCB1;ABCC2 GO:0006955| immune response OPRD1;OPRK1;TNFSF11 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRM1;OPRK1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 37678:[DB00480 DB07625] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07625|4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PLAU GO:0042127| regulation of cell proliferation PLAU;PTGS2 37679:[DB00480 DB00024] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00024|Thyrotropin alfa TSHR common genes common pathways GO:0008284| positive regulation of cell proliferation TSHR;PTGS2 37680:[DB00480 DB05814] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05814|GPI-1485 FKBP1A;CYP3A4 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CDH5 37681:[DB00480 DB09201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09201|Ciglitazone PPARG;CYP3A4;CYP2C8 common genes common pathways GO:0042493| response to drug ABCB1;PPARG;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0010033| response to organic substance PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG;CYP3A4 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 37682:[DB00480 DB03616] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03616|Kabiramide C ACTA1 common genes common pathways GO:0010226| response to lithium ion PTGS2;ACTA1 37683:[DB00480 DB08844] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0055085| transmembrane transport SLC22A6;SLC22A8;ABCB1;SLC2A9 37684:[DB00480 DB07557] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07557|(5BETA)-PREGNANE-3,20-DIONE NCOA1;RXRA;NR1I3;AKR1D1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;RXRA;TNFSF11;NCOA1 GO:0055114| oxidation-reduction process PTGS2;AKR1D1 GO:0043065| positive regulation of apoptotic process NCOA1;PTGS2 GO:0006629| lipid metabolic process PTGS2;AKR1D1 GO:0007566| embryo implantation RXRA;PTGS2 37685:[DB00480 DB01375] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01375|Aluminium monostearate TNNC1;VDAC1;VDAC2;VDAC3 common genes common pathways GO:0055085| transmembrane transport ABCB1;VDAC3;VDAC2;VDAC1 GO:0007612| learning VDAC3;VDAC1;PTGS2 37686:[DB00480 DB07945] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07945|5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0050873| brown fat cell differentiation FABP4;PTGS2 37687:[DB00480 DB09110] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09110|Coenzyme M GSR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GSR GO:0098869| PTGS2;GSR 37688:[DB00480 DB00810] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 37689:[DB00480 DB08382] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08382|Gosogliptin DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion CDH5;DPP4 37690:[DB00480 DB09460] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09460|Sodium carbonate CA1;CA2;CA4;CA9 common genes common pathways GO:0045780| positive regulation of bone resorption CA2;TNFSF11 GO:0010033| response to organic substance PTGS2;CA2 GO:0042493| response to drug ABCB1;CA9;PTGS2 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 37691:[DB00480 DB01405] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 37692:[DB00480 DB02613] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02613|Decylamine-N,N-Dimethyl-N-Oxide DHODH;PNLIPRP2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0006629| lipid metabolic process PTGS2;PNLIPRP2 GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0042493| response to drug DHODH;PTGS2;ABCB1 37693:[DB00480 DB05361] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;F2R GO:0008284| positive regulation of cell proliferation F2R;PTGS2 GO:0045907| positive regulation of vasoconstriction F2R;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;F2R GO:0008285| negative regulation of cell proliferation PTGS2;F2R;CDH5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade F2R;TNFSF11 GO:0006954| inflammatory response F2R;PTGS2 37694:[DB00480 DB08875] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08875|Cabozantinib MET;KDR;RET;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0042493| response to drug ABCB1;RET;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP2C9;CYP3A4 GO:0007156| homophilic cell adhesion CDH5;RET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 GO:0008284| positive regulation of cell proliferation KDR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0007155| cell adhesion RET;CDH5 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0001525| angiogenesis PTGS2;KDR GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS2 GO:0030154| cell differentiation TNFSF11;KDR 37695:[DB00480 DB08784] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08784|2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID NMRAL1 common genes common pathways 37696:[DB00480 DB02285] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02285|Protoporphyrin FTL common genes common pathways 37697:[DB00480 DB00038] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00038|Oprelvekin IL11RA common genes common pathways GO:0007566| embryo implantation PTGS2;IL11RA GO:0019221| cytokine-mediated signaling pathway IL11RA;TNFSF11 37698:[DB00480 DB07249] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07249|N-(5-chloro-1,3-benzodioxol-4-yl)-6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-amine EPHB4 common genes common pathways GO:0001525| angiogenesis EPHB4;PTGS2 GO:0007275| multicellular organismal development TNFSF11;EPHB4 GO:0007155| cell adhesion CDH5;EPHB4 37699:[DB00480 DB04448] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04448|2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;PTGS2 37700:[DB00480 DB00865] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;POR GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0043066| negative regulation of apoptotic process POR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA2A GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;POR;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug ABCB1;POR;PTGS2;ADRA1A;SLC6A3 GO:0007568| aging ADRA1A;SLC6A3;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC18A2 37701:[DB00480 DB06231] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06231|Caldaret SLC8A1 common genes common pathways GO:0055074| calcium ion homeostasis TNFSF11;SLC8A1 GO:0071456| cellular response to hypoxia PTGS2;SLC8A1 GO:0055085| transmembrane transport SLC8A1;ABCB1 GO:0042493| response to drug PTGS2;SLC8A1;ABCB1 37702:[DB00480 DB13941] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP3A4;CYP2E1;PTGS2;CYP2C19 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 37703:[DB00480 DB03189] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03189|Cu-Cyclam LYZ common genes common pathways GO:0006954| inflammatory response PTGS2;LYZ 37704:[DB00480 DB00160] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways GO:0042493| response to drug ABAT;ABCB1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;AGXT2 GO:0006810| transport SLC7A8;ABCB1 GO:0007568| aging PTGS2;ABAT GO:0055085| transmembrane transport SLC36A1;SLC16A10;ABCB1;SLC1A4 GO:0051384| response to glucocorticoid stimulus AGXT;PTGS2 37705:[DB00480 DB03020] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03020|5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 37706:[DB00480 DB00596] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 37707:[DB00480 DB07008] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07008|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 37708:[DB00480 DB00094] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00094|Urofollitropin FSHR common genes common pathways GO:0045670| regulation of osteoclast differentiation FSHR;TNFSF11 37709:[DB00480 DB00189] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRG2;ABCB1;GABRA1;GABRB3;GABRB1;GABRA6;GABRA4;GABRD;GABRA3;GABRA5;GABRB2 GO:0042493| response to drug PTGS2;GABRG3;ABCB1 37710:[DB00480 DB11639] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11639|Dibotermin alfa BMPR2;BMPR1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;BMPR1A GO:0042127| regulation of cell proliferation BMPR2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter BMPR2;BMPR1A;TNFSF11 GO:0030154| cell differentiation TNFSF11;BMPR1A GO:0006955| immune response TNFSF11;BMPR1A 37711:[DB00480 DB11075] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11075|Hypromellose EPCAM common genes common pathways GO:0098609| CDH5;EPCAM GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EPCAM GO:0008284| positive regulation of cell proliferation PTGS2;EPCAM 37712:[DB00480 DB01366] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01366|Procaterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0050873| brown fat cell differentiation PTGS2;ADRB2 37713:[DB00480 DB00385] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00385|Valrubicin TOP2A common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 37714:[DB00480 DB14596] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0070542| response to fatty acid PTGS2;PON1 GO:0006629| lipid metabolic process PTGS2;PON1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0019372| lipoxygenase pathway PTGS2;PON1 37715:[DB00480 DB01440] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process PTGS2;SLC16A1 GO:0006810| transport GABRB1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC16A7;SLC16A1;SLC16A3 37716:[DB00480 DB00920] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00920|Ketotifen HRH1;PGD common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0055114| oxidation-reduction process PGD;PTGS2 37717:[DB00480 DB04207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04207|N-(5-Amino-5-Carboxypentyl)Glutamic Acid AASS common genes common pathways GO:0055114| oxidation-reduction process PTGS2;AASS 37718:[DB00480 DB12781] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12781|Balaglitazone CYP3A4;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A4 37719:[DB00480 DB01623] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0007613| memory DRD1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process CYP1A2;CYP2D6;PTGS2 GO:0055085| transmembrane transport SLC22A1;ABCB1 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0007568| aging HTR2A;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0098869| ALB;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;HTR2A;DRD1;DRD2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;CYP2D6;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0007612| learning DRD1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0043066| negative regulation of apoptotic process PTGS2;ALB 37720:[DB00480 DB00857] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;CYP2C9;CYP2D6;CYP11A1;CYP1A2;SQLE;CYP2C8;CYP2C19;PTGS2;PTGS1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;SQLE;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP11A1;CYP1A2;CYP3A4;PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 37721:[DB00480 DB04829] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2B GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0042493| response to drug ABCB1;PTGS2;HTR2B GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HTR2B GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 37722:[DB00480 DB08168] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08168|7-AMINO-4-METHYL-CHROMEN-2-ONE PPIF;HDAC8 common genes common pathways GO:0043066| negative regulation of apoptotic process PPIF;PTGS2 GO:0006979| response to oxidative stress PTGS2;PPIF 37723:[DB00480 DB13997] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0055085| transmembrane transport ABCB5;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006855| drug transmembrane transport ABCB5;ABCB1 GO:0042908| xenobiotic transport ABCB5;ABCB1 GO:0030154| cell differentiation TNFSF11;ABCB5 37724:[DB00480 DB03958] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03958|7-methyl-guanosine-5'-triphosphate-5'-guanosine DCPS common genes common pathways 37725:[DB00480 DB01083] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;PNLIP;FASN;CYP3A4;LIPF;PTGS2 GO:0006633| fatty acid biosynthetic process FASN;PTGS2 GO:0042127| regulation of cell proliferation PLA2G4A;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;FASN GO:0055114| oxidation-reduction process LIPF;PTGS2;FASN;CYP3A4 37726:[DB00480 DB08044] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08044|ABT-341 DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion CDH5;DPP4 37727:[DB00480 DB14582] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways GO:0006954| inflammatory response PTGS2;ORM1 GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 37728:[DB00480 DB00691] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0042127| regulation of cell proliferation ACE2;PTGS2 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC15A2 GO:0050727| regulation of inflammatory response PTGS2;ACE2 GO:0008217| regulation of blood pressure PTGS2;ACE 37729:[DB00480 DB02322] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02322|Heparin Disaccharide I-S CCL5 common genes common pathways GO:0034112| positive regulation of homotypic cell-cell adhesion TNFSF11;CCL5 GO:0048661| positive regulation of smooth muscle cell proliferation CCL5;PTGS2 GO:0002548| monocyte chemotaxis CCL5;TNFSF11 GO:0034097| response to cytokine stimulus PTGS2;CCL5 GO:0034612| response to tumor necrosis factor CCL5;PTGS2 GO:0010469| regulation of receptor activity CCL5;TNFSF11 GO:0006954| inflammatory response CCL5;PTGS2 GO:0006955| immune response TNFSF11;CCL5 GO:0042327| positive regulation of phosphorylation CCL5;TNFSF11 37730:[DB00480 DB05442] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0019221| cytokine-mediated signaling pathway IL1B;TNFSF11 GO:0046330| positive regulation of JNK cascade TNFSF11;IL1B GO:0032496| response to lipopolysaccharide IL1B;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;TNFSF11 GO:0010469| regulation of receptor activity IL1B;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process IL1B;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;TNFSF11 GO:0006954| inflammatory response IL1B;PTGS2 GO:0006955| immune response IL1B;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;TNFSF11 GO:0031622| positive regulation of fever generation IL1B;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production IL1B;PTGS2 GO:0071260| cellular response to mechanical stimulus IL1B;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;IL1B;PTGS2 GO:0007566| embryo implantation PTGS2;IL1B 37731:[DB00480 DB03864] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03864|Monothioglycerol PREP common genes common pathways 37732:[DB00480 DB09060] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0055085| transmembrane transport SLC22A8;ABCB1;ABCC2 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0006810| transport ABCC2;ABCB1 GO:0042493| response to drug PTGS2;ABCB1;ABCC2 GO:0032496| response to lipopolysaccharide ABCC2;PTGS2 37733:[DB00480 DB04733] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04733|1,6-DI-O-PHOSPHONO-D-MANNITOL ALDOA common genes common pathways 37734:[DB00480 DB00434] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A;CHRM1 GO:0042493| response to drug ABCB1;HTR2C;PTGS2;HTR2A GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0007613| memory HRH1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;HTR2A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 37735:[DB00480 DB00949] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0007612| learning PTGS2;GRIN2A GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2C19;PTGS2;CYP2E1 GO:0042493| response to drug GRIN2A;ABCB1;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0006810| transport ABCB1;GRIN2A;GRIN2B GO:0019233| sensory perception of pain PTGS2;GRIN2A GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP3A4 GO:0043065| positive regulation of apoptotic process PTGS2;GRIN2A GO:0007613| memory GRIN2A;PTGS2 GO:0019722| calcium-mediated signaling GRIN2B;GRIN2A;TNFSF11 37736:[DB00480 DB08594] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08594|TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 37737:[DB00480 DB04114] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04114|3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 37738:[DB00480 DB08912] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes ABCB1 common pathways GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS2 GO:0007275| multicellular organismal development RAF1;SIK1;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;RAF1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BRAF;RAF1;PTGS2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0030154| cell differentiation RAF1;TNFSF11;SIK1;BRAF GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0008285| negative regulation of cell proliferation CDH5;RAF1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0043066| negative regulation of apoptotic process RAF1;PTGS2;BRAF GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;BRAF GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2B6;CYP2C8;PTGS2 GO:0042493| response to drug PTGS2;ABCG2;ABCB1 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006810| transport ABCB1;ABCG2 GO:0009887| organ morphogenesis BRAF;TNFSF11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLC22A6;SLCO1B1;SLC22A8;ABCG2 37739:[DB00480 DB01599] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01599|Probucol ABCA1;CES1 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;ABCA1 GO:0055085| transmembrane transport ABCA1;ABCB1 GO:0006629| lipid metabolic process ABCA1;PTGS2 GO:0045332| phospholipid translocation ABCA1;ABCB1 37740:[DB00480 DB04559] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04559|N-(Chlorophenyl)-N'-Hydroxyguanidine NOS3 common genes common pathways GO:0001525| angiogenesis NOS3;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;NOS3 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process NOS3;PTGS2 37741:[DB00480 DB02485] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02485|Cytidine-5'-Monophosphate-5-N-Acetylneuraminic Acid CMAS common genes common pathways 37742:[DB00480 DB09046] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09046|Metreleptin LEPR common genes common pathways GO:0007275| multicellular organismal development TNFSF11;LEPR GO:0001525| angiogenesis PTGS2;LEPR 37743:[DB00480 DB08153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08153|(5E)-14-CHLORO-15,17-DIHYDROXY-4,7,8,9,10,11-HEXAHYDRO-2-BENZOXACYCLOPENTADECINE-1,12(3H,13H)-DIONE HSP90AB1 common genes common pathways GO:0042493| response to drug ABCB1;HSP90AB1;PTGS2 GO:0043066| negative regulation of apoptotic process HSP90AB1;PTGS2 GO:0010033| response to organic substance PTGS2;HSP90AB1 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AB1;PTGS2 37744:[DB00480 DB04250] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04250|Butyrylthiocholine BCHE;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0007612| learning BCHE;PTGS2 GO:0042493| response to drug BCHE;ABCB1;PTGS2 37745:[DB00480 DB05936] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05936|CVT-6883 ADORA2B common genes common pathways GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;ADORA2B 37746:[DB00480 DB08426] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08426|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 37747:[DB00480 DB00347] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP3A4 GO:0055085| transmembrane transport ABCB1;CACNA1G GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2E1;CYP2C8;CYP2C19;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 37748:[DB00480 DB03305] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03305|N5-Iminoethyl-L-Ornithine NOS3 common genes common pathways GO:0001525| angiogenesis PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;NOS3;CDH5 GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 37749:[DB00480 DB01736] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01736|[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium SLC25A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC25A4 GO:0006810| transport ABCB1;SLC25A4 37750:[DB00480 DB03604] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03604|Tiratricol THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TNFSF11 GO:0009887| organ morphogenesis TNFSF11;THRB 37751:[DB00480 DB00132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00132|Alpha-Linolenic Acid FADS1;FADS2;SLC8A1;TRPV1;ELOVL4;PPARA;NR1H4;PPARD;PPARG;RXRA;FABP7 common genes common pathways GO:0071318| cellular response to ATP TRPV1;PTGS2 GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0043066| negative regulation of apoptotic process PPARD;NR1H4;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG;RXRA;PPARA;NR1H4 GO:0055114| oxidation-reduction process FADS2;PTGS2;FADS1 GO:0006631| fatty acid metabolic process FADS2;PTGS2;ELOVL4;PPARA;FADS1 GO:0042493| response to drug PTGS2;SLC8A1;ABCB1;PPARG GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0050728| negative regulation of inflammatory response PPARA;PPARD;CDH5;NR1H4 GO:0046697| decidualization PTGS2;PPARD GO:0006810| transport ABCB1;TRPV1 GO:0071456| cellular response to hypoxia PPARD;PTGS2;SLC8A1 GO:0034605| cellular response to heat PTGS2;TRPV1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2 GO:0007043| cell-cell junction assembly CDH5;NR1H4 GO:0055085| transmembrane transport ABCB1;TRPV1;SLC8A1 GO:0010033| response to organic substance PTGS2;PPARG;PPARD GO:0019233| sensory perception of pain TRPV1;PTGS2 GO:0006629| lipid metabolic process TRPV1;FADS2;PTGS2;ELOVL4;PPARG;FADS1;PPARD;PPARA GO:0043065| positive regulation of apoptotic process PPARG;TRPV1;PTGS2 GO:0055074| calcium ion homeostasis TNFSF11;SLC8A1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0006954| inflammatory response NR1H4;TRPV1;PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0007566| embryo implantation PPARD;RXRA;PTGS2 GO:0006633| fatty acid biosynthetic process ELOVL4;FADS1;FADS2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;FABP7;CDH5;PPARG 37752:[DB00480 DB11755] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0042493| response to drug ABCB1;TRPA1;PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;CDH5 GO:0032496| response to lipopolysaccharide CNR1;PTGS2;CNR2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 GO:0055085| transmembrane transport TRPV2;TRPM8;ABCB1;TRPA1 GO:0010033| response to organic substance PTGS2;TRPA1 GO:0006810| transport TRPV2;ABCB1 GO:0007568| aging CNR1;PTGS2 GO:0006955| immune response CNR2;TNFSF11 GO:0006954| inflammatory response CNR2;PTGS2 GO:0019233| sensory perception of pain PTGS2;CNR2;CNR1;TRPA1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0043065| positive regulation of apoptotic process CNR1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;TRPA1 GO:0007613| memory CNR1;PTGS2 GO:0045453| bone resorption TNFSF11;GPR55 37753:[DB00480 DB03129] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03129|[3-(1,3,2-Dioxaborolan-2-Yloxy)Propyl]Guanidine PRSS3 common genes common pathways 37754:[DB00480 DB00378] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11 37755:[DB00480 DB04672] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04672|cyclic 3',5'-thymidine monophosphate NT5M common genes common pathways 37756:[DB00480 DB06140] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06140|SUVN-502 HTR6 common genes common pathways 37757:[DB00480 DB00702] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00702|Icodextrin AMY2A common genes common pathways 37758:[DB00480 DB01425] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01425|Alizapride DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0042493| response to drug DRD2;PTGS2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 37759:[DB00480 DB01057] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01057|Echothiophate BCHE;ALB common genes common pathways GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0098869| ALB;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;BCHE;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE 37760:[DB00480 DB01998] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways 37761:[DB00480 DB13168] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes PTGS2 common pathways GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response ALOX5;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process FADS2;PTGS2;FADS1 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process FADS2;PTGS2;FADS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process FADS1;FADS2;ALOX5;PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0006631| fatty acid metabolic process FADS2;PTGS2;FADS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 37762:[DB00480 DB03066] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A3;SLC16A7;SLC16A1;ABCB1 GO:0006629| lipid metabolic process PTGS2;SLC16A1 37763:[DB00480 DB11892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11892|Prulifloxacin CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 37764:[DB00480 DB06756] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;CDH5;BCL2;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BCL2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCL2;BCHE GO:0010942| positive regulation of cell death PRODH;PTGS2 GO:0009314| response to radiation PTGS2;BCL2 GO:0001503| ossification BCL2;TNFSF11 GO:0009887| organ morphogenesis TNFSF11;BCL2 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0006979| response to oxidative stress PTGS2;BCL2 GO:0098609| CDH5;BCL2 GO:0071456| cellular response to hypoxia PTGS2;BCL2 GO:0042493| response to drug PTGS2;ABCB1;BCHE;BCL2 GO:0055114| oxidation-reduction process PTGS2;PRODH GO:0008284| positive regulation of cell proliferation PTGS2;BCL2 GO:0043066| negative regulation of apoptotic process BCL2;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;BCL2 GO:0007612| learning PTGS2;BCHE 37765:[DB00480 DB07389] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07389|N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE NOS2 common genes common pathways GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0055114| oxidation-reduction process PTGS2;NOS2 37766:[DB00480 DB03073] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03073|3-Methoxybenzamide PARP1 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 37767:[DB00480 DB03009] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03009|2-[(2-Oxo-2-Piperidin-1-Ylethyl)Thio]-6-(Trifluoromethyl)Pyrimidin-4(1h)-One FABP4 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;FABP4 GO:0050873| brown fat cell differentiation FABP4;PTGS2 37768:[DB00480 DB09332] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0008284| positive regulation of cell proliferation F2;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;POR;PROC GO:0055114| oxidation-reduction process PTGS2;VKORC1;POR GO:0042493| response to drug POR;ABCB1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11;F7 GO:0050728| negative regulation of inflammatory response PROC;CDH5 GO:0010469| regulation of receptor activity F2;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0007275| multicellular organismal development F2;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process POR;PTGS2 GO:1903142| PROC;CDH5 GO:0014070| response to organic cyclic compound F7;PTGS2 37769:[DB00480 DB01750] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01750|1-naphthaleneacetic acid SKP1 common genes common pathways GO:0016567| protein ubiquitination SKP1;CRBN GO:0000086| G2/M transition of mitotic cell cycle ABCB1;SKP1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;SKP1 37770:[DB00480 DB02596] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02596|Alpha,Beta-Methyleneadenosine-5'-Triphosphate folK;panC;nadE;NMNAT3;carA common genes common pathways 37771:[DB00480 DB05327] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05327|Ranirestat AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0010033| response to organic substance PTGS2;AKR1B1 37772:[DB00480 DB08051] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08051|(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion DPP4;CDH5 37773:[DB00480 DB08127] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08127|1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene CRABP2 common genes common pathways 37774:[DB00480 DB03023] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:1902533| SRC;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0034605| cellular response to heat LYN;PTGS2 GO:0098609| SRC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;LCK;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug ABCB1;LYN;LCK;PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0008284| positive regulation of cell proliferation PTGS2;LYN GO:0042127| regulation of cell proliferation SRC;PTGS2;LCK GO:0008285| negative regulation of cell proliferation PTGS2;LYN;CDH5 GO:0014070| response to organic cyclic compound PTGS2;LYN GO:0070542| response to fatty acid SRC;PTGS2 GO:0050870| positive regulation of T cell activation TNFSF11;LCK GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption TNFSF11;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0006954| inflammatory response PTGS2;LYN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0042327| positive regulation of phosphorylation LYN;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;LYN GO:0043065| positive regulation of apoptotic process PTGS2;SRC 37775:[DB00480 DB11779] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11779|Danoprevir CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37776:[DB00480 DB04930] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04930|Permethrin SCN1A;ESR1;NR1I2;CYP2B6;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN1A GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0055114| oxidation-reduction process CYP2B6;CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2;ESR1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37777:[DB00480 DB06419] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP3A5 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37778:[DB00480 DB07274] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07274|N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide KDR common genes common pathways GO:0030154| cell differentiation TNFSF11;KDR GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0001525| angiogenesis KDR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0008284| positive regulation of cell proliferation PTGS2;KDR 37779:[DB00480 DB11960] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37780:[DB00480 DB07979] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07979|(2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID DAO common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DAO 37781:[DB00480 DB07827] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07827|4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13 37782:[DB00480 DB03344] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03344|Inositol-(1,3,4,5,6)-Pentakisphosphate CYTH3 common genes common pathways 37783:[DB00480 DB05130] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05130|INCB3284 CCR2 common genes common pathways GO:0002548| monocyte chemotaxis TNFSF11;CCR2 GO:0019221| cytokine-mediated signaling pathway CCR2;TNFSF11 GO:0050870| positive regulation of T cell activation CCR2;TNFSF11 GO:0019233| sensory perception of pain PTGS2;CCR2 GO:0006954| inflammatory response PTGS2;CCR2 GO:0006955| immune response TNFSF11;CCR2 37784:[DB00480 DB07060] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07060|3-(INDOL-3-YL) LACTATE HAO1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HAO1 GO:0006979| response to oxidative stress PTGS2;HAO1 37785:[DB00480 DB08834] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCB1 GO:0006979| response to oxidative stress PTGS2;SLC7A11 37786:[DB00480 DB07843] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07843|5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 37787:[DB00480 DB03153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 37788:[DB00480 DB12651] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12651|Bardoxolone CASP8 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP8;TNFSF11 GO:0071260| cellular response to mechanical stimulus CASP8;PTGS2 GO:0032355| response to estradiol stimulus CASP8;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;CASP8 GO:0032496| response to lipopolysaccharide PTGS2;CASP8 37789:[DB00480 DB00298] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00298|Dapiprazole ADRA1A;ADRA1D;ADRA1B common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;PTGS2;ADRA1B GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B;ADRA1A;ADRA1D GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0007568| aging ADRA1A;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0008284| positive regulation of cell proliferation ADRA1D;PTGS2 37790:[DB00480 DB12489] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37791:[DB00480 DB00145] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0008284| positive regulation of cell proliferation SHMT2;PTGS2 GO:0007612| learning PTGS2;GRIN2A GO:0055114| oxidation-reduction process PTGS2;PIPOX;GLDC GO:0006631| fatty acid metabolic process PTGS2;BAAT GO:0042493| response to drug ABCB1;GRIN2A;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process AGXT2;PTGS2 GO:0006979| response to oxidative stress PTGS2;GSS GO:0051260| protein homooligomerization TNFSF11;GLRA3;GLRA1 GO:0006810| transport ABCB1;GRIN2A;GRIN2C;SLC6A5;SLC6A9 GO:0007568| aging SLC32A1;PTGS2;GSS GO:1990830| SHMT1;GLDC;TNFSF11 GO:0055085| transmembrane transport SLC6A9;SLC36A1;SLC6A5;ABCB1;SLC16A10 GO:0034612| response to tumor necrosis factor GSS;PTGS2 GO:0006629| lipid metabolic process BAAT;PTGS2 GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2 GO:0019233| sensory perception of pain GRIN2A;PTGS2 GO:0007275| multicellular organismal development TNFSF11;GATM GO:0007613| memory PTGS2;GRIN2A GO:0019722| calcium-mediated signaling GRIN2C;TNFSF11;GRIN2A GO:0051384| response to glucocorticoid stimulus AGXT;PTGS2 37792:[DB00480 DB08892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A1 GO:0006629| lipid metabolic process SLC16A1;PTGS2 37793:[DB00480 DB04410] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04410|3-Phenylpropylamine PRSS2;PRSS1 common genes common pathways 37794:[DB00480 DB00830] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0007568| aging PTGS2;SLC6A3 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A3;SLC6A2 GO:0042493| response to drug ABCB1;SLC6A3;PTGS2;SLC6A2 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 37795:[DB00480 DB11805] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11805|Saracatinib CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 37796:[DB00480 DB01708] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0042493| response to drug PTGS2;GABRG3;GRIN2A;ABCB1 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;HSD17B1;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0007612| learning GRIN1;PTGS2;GRIN2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2;ESR1;PPARA;ESR2;GRIN1;AR;NR1I3 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development AR;ESR1;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0006810| transport GRIN2C;GABRD;GABRB1;GABRA4;GABRA6;GABRA5;GABRA3;GABRB2;AR;ABCB1;GABRG2;GRIN2B;GRIN2A;GABRA1;GABRB3 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1;TNFSF11 GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0019233| sensory perception of pain GRIN1;PTGS2;GRIN2A GO:0043065| positive regulation of apoptotic process PTGS2;GRIN1;GRIN2A GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0006629| lipid metabolic process SULT2A1;PPARA;CYP3A4;SULT2B1;HSD17B1;PTGS2 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5;SULT2B1 GO:0019722| calcium-mediated signaling GRIN2C;GRIN1;GRIN2A;GRIN2B;TNFSF11;GRIN2D GO:0007613| memory GRIN2A;GRIN1;PTGS2 GO:0042908| xenobiotic transport NR1I2;ABCB1 37797:[DB00480 DB14017] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14017|H3B-8800 SF3B1 common genes common pathways 37798:[DB00480 DB06346] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06346|Fiboflapon ALOX5AP common genes common pathways GO:0019372| lipoxygenase pathway PTGS2;ALOX5AP 37799:[DB00480 DB04861] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP3A4 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 37800:[DB00480 DB03918] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03918|6S-5,6,7,8-Tetrahydrobiopterin NOS3 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS3 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;NOS3;CDH5 GO:0001525| angiogenesis NOS3;PTGS2 37801:[DB00480 DB00052] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00052|Somatotropin GHR;PRLR common genes common pathways GO:0060749| mammary gland alveolus development PRLR;TNFSF11 GO:0043066| negative regulation of apoptotic process PRLR;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;GHR GO:0019221| cytokine-mediated signaling pathway GHR;TNFSF11 GO:0032355| response to estradiol stimulus GHR;PTGS2 GO:0007566| embryo implantation PRLR;PTGS2 37802:[DB00480 DB05967] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05967|ANZ-100 KISS1R common genes common pathways 37803:[DB00480 DB12243] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A8 37804:[DB00480 DB05448] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05448|PX-12 TXNRD1 common genes common pathways GO:0098869| TXNRD1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;TXNRD1 37805:[DB00480 DB09198] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes ABCB1 common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:1901529| ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0042493| response to drug CYP1A2;ABCB1;PPARG;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;CYP2C9;CYP3A4;PTGS2;CYP2C19;CYP2C8 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO3A1;SLCO1B1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance PTGS2;PPARG;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2C9;CYP3A4;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0014070| response to organic cyclic compound PTGS2;PPARG;CYP1A2 GO:0006855| drug transmembrane transport ABCB1 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG 37806:[DB00480 DB11421] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11421|Imidacloprid CHRFAM7A common genes common pathways 37807:[DB00480 DB07151] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07151|4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one PIM1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2 37808:[DB00480 DB04282] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04282|2-deoxy-2-fluoro-α-D-glucose LCT common genes common pathways 37809:[DB00480 DB11830] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11830|Mocetinostat HDAC1;HDAC3;HDAC2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;HDAC2;HDAC1 GO:0008284| positive regulation of cell proliferation HDAC2;PTGS2;HDAC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;HDAC1;HDAC3;TNFSF11 GO:0043066| negative regulation of apoptotic process HDAC2;PTGS2;HDAC1;HDAC3 GO:0032496| response to lipopolysaccharide HDAC1;PTGS2;HDAC2 GO:0034605| cellular response to heat PTGS2;HDAC2 GO:0071498| cellular response to fluid shear stress PTGS2;HDAC3 GO:0008285| negative regulation of cell proliferation PTGS2;HDAC1;CDH5 37810:[DB00480 DB02080] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02080|1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene PLA2G2A;lepB;TTPA common genes common pathways GO:0006810| transport ABCB1;TTPA GO:0006629| lipid metabolic process PTGS2;TTPA;PLA2G2A 37811:[DB00480 DB03298] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03298|Phenylphosphate SRC common genes common pathways GO:0070542| response to fatty acid SRC;PTGS2 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC 37812:[DB00480 DB05532] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05532|BMS-488043 FFAR4 common genes common pathways GO:0050728| negative regulation of inflammatory response FFAR4;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;FFAR4 37813:[DB00480 DB05449] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05449|FM-VP4 ABCB1 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 37814:[DB00480 DB07180] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07180|5-[(Z)-(5-Chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N,2,4-trimethyl-1H-pyrrole-3-carboxamide NEK2 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle NEK2;ABCB1 37815:[DB00480 DB09348] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09348|Propiolactone ALB common genes common pathways GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB 37816:[DB00480 DB14001] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14001|alpha-Tocopherol succinate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0043065| positive regulation of apoptotic process SOD1;HMOX1;PTGS2 GO:0071260| cellular response to mechanical stimulus GCLC;PTGS2 GO:0006629| lipid metabolic process PTGS2;TTPA GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;PRKCB;HMOX1 GO:0001525| angiogenesis PRKCA;HMOX1;PTGS2 GO:0006954| inflammatory response ALOX5;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;PRKCB GO:0007566| embryo implantation PTGS2;SOD1 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0008217| regulation of blood pressure SOD1;HMOX1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;HMOX1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;NQO1 GO:0043066| negative regulation of apoptotic process SOD1;GSTP1;PTGS2;GCLC;NQO1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2 GO:0007155| cell adhesion CDH5;PRKCA GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMOX1 GO:0042493| response to drug SOD1;PTGS2;ABCB1 GO:0055114| oxidation-reduction process ALOX5;SOD1;HMOX1;PTGS2;GSTO1;NQO1 GO:0098869| GSTO1;GSTP1;PTGS2 GO:0006979| response to oxidative stress NQO1;GCLC;HMOX1;SOD1;PTGS2 GO:0051260| protein homooligomerization TNFSF11;HMOX1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process PPP2CB;CRBN GO:0034605| cellular response to heat PTGS2;HMOX1 GO:0045780| positive regulation of bone resorption TNFSF11;PRKCA GO:0032355| response to estradiol stimulus GSTP1;PTGS2;NQO1 GO:0006810| transport ABCB1;TTPA GO:0007568| aging PTGS2;SOD1;GCLC;NQO1 GO:0071456| cellular response to hypoxia PTGS2;HMOX1 GO:0010033| response to organic substance PPP2CA;PTGS2;SOD1 37817:[DB00480 DB04988] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04988|IGN311 EGFR;ERBB2 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;ERBB2;EGFR GO:0008284| positive regulation of cell proliferation EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity ERBB2;EGFR;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0006979| response to oxidative stress EGFR;PTGS2 GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0098609| CDH5;EGFR GO:0042327| positive regulation of phosphorylation TNFSF11;EGFR GO:0001503| ossification EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0014070| response to organic cyclic compound PTGS2;EGFR GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 37818:[DB00480 DB08058] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08058|4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one PARP3 common genes common pathways 37819:[DB00480 DB01760] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01760|2-Methoxy-3-Isopropylpyrazine LCN9 common genes common pathways 37820:[DB00480 DB07739] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07739|(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE PNMT common genes common pathways 37821:[DB00480 DB09539] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09539|Omega-3-acid ethyl esters SOAT1 common genes common pathways GO:0006629| lipid metabolic process SOAT1;PTGS2 37822:[DB00480 DB03953] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03953|L-Thiocitrulline NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;NOS2 37823:[DB00480 DB02933] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02933|5'-Deoxy-5'-(Methylthio)-Tubercidin MTAP common genes common pathways 37824:[DB00480 DB02056] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;AKR1C3 GO:0055114| oxidation-reduction process PTGS2;AKR1C3 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;AKR1C3 GO:0055085| transmembrane transport ABCB1;SLCO2A1 GO:0006693| prostaglandin metabolic process AKR1C3;PTGS2 GO:0019371| cyclooxygenase pathway AKR1C3;PTGS2 GO:0010942| positive regulation of cell death AKR1C3;PTGS2 GO:0006955| immune response TNFSF11;PTGDR2 GO:0019722| calcium-mediated signaling TNFSF11;PTGDR2 37825:[DB00480 DB01294] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 37826:[DB00480 DB04723] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04723|2-(3-GUANIDINOPHENYL)-3-MERCAPTOPROPANOIC ACID CPB1 common genes common pathways 37827:[DB00480 DB04821] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0007613| memory SLC6A4;PTGS2 GO:0006954| inflammatory response ORM1;PTGS2 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A2;SLC18A2;SLC6A3 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0006979| response to oxidative stress PTGS2;MPO GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0007568| aging PTGS2;MPO;SLC6A3 GO:0006810| transport SLC6A2;ABCB1 GO:0042493| response to drug SLC6A4;ABCB1;SLC6A3;MAOB;PTGS2;SLC6A2 GO:0055114| oxidation-reduction process MAOB;MPO;PTGS2;MAOA GO:0043066| negative regulation of apoptotic process MPO;PTGS2 GO:0032496| response to lipopolysaccharide MPO;MAOB;PTGS2 37828:[DB00480 DB04653] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04653|CBZ-LEU-LEU-TYR-CH2F CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPN1;PTGS2 37829:[DB00480 DB02565] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02565|4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide HDAC8 common genes common pathways 37830:[DB00480 DB03166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03166|Acetic acid SLCO2B1;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;SLC16A1 GO:0055085| transmembrane transport SLC16A1;ABCB1;SLCO2B1 37831:[DB00480 DB01075] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01075|Diphenhydramine HRH1;CHRM2;CYP2D6;CYP2C9;CYP2C19;CYP2C18;PTGS1;SLC22A2;SLC22A5 common genes common pathways GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0055085| transmembrane transport SLC22A5;SLC22A2;ABCB1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP2C19;PTGS2;CYP2C18;PTGS1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5;SLC22A2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;PTGS2;HRH1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 37832:[DB00480 DB07616] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07616|4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid HPGDS common genes common pathways GO:0019371| cyclooxygenase pathway PTGS2;HPGDS GO:0006693| prostaglandin metabolic process HPGDS;PTGS2 GO:0006629| lipid metabolic process HPGDS;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0006631| fatty acid metabolic process HPGDS;PTGS2 37833:[DB00480 DB07136] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07136|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(R)-HYDROXY[(1R)-2-METHYL-1-{[(3-PHENYLPROPYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 37834:[DB00480 DB04576] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 37835:[DB00480 DB02337] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 37836:[DB00480 DB14641] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0006810| transport ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;ESR2 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 37837:[DB00480 DB00116] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00116|Tetrahydrofolic acid MTHFD1;MTHFD2;AMT;ALDH1L1;MTR;FTCD;ATIC;SHMT1;SHMT2;MTHFR;MTFMT;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0006810| transport ABCC2;ABCB1 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:1990830| SHMT1;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:0008284| positive regulation of cell proliferation PTGS2;SHMT2 GO:0042493| response to drug PTGS2;MTHFR;ABCB1;ABCC2 GO:0055114| oxidation-reduction process PTGS2;ALDH1L1;MTHFD1;MTHFD2;MTHFR 37838:[DB00480 DB02158] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02158|(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol MTAP common genes common pathways 37839:[DB00480 DB05033] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05033|INCB7839 ADAM9 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;ADAM9 GO:0034612| response to tumor necrosis factor ADAM9;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;ADAM9 GO:0007155| cell adhesion ADAM9;CDH5 GO:0010042| response to manganese ion ADAM9;PTGS2 37840:[DB00480 DB13998] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0051260| protein homooligomerization TNFSF11;VWF GO:0010469| regulation of receptor activity F2;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;CALR GO:0030282| bone mineralization ASGR2;PTGS2 GO:0007568| aging PTGS2;LRP1;CANX GO:0010033| response to organic substance PTGS2;CALR GO:0008284| positive regulation of cell proliferation CALR;F2;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HSPA5;PROC GO:0007155| cell adhesion VWF;CDH5 GO:0050728| negative regulation of inflammatory response PROC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 GO:0042493| response to drug ABCB1;CALR;PTGS2 GO:0006631| fatty acid metabolic process PHYH;PTGS2 GO:0055114| oxidation-reduction process PHYH;PTGS2 GO:1903142| CDH5;PROC GO:0009314| response to radiation PTGS2;HSPA5 GO:0006629| lipid metabolic process PTGS2;LRP1 GO:0007275| multicellular organismal development TNFSF11;LRP1;F2 GO:0010942| positive regulation of cell death PTGS2;LRP1 37841:[DB00480 DB08835] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08835|Spaglumic Acid FOLH1;SLC36A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC36A1 37842:[DB00480 DB05460] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05460|Ezatiostat GSTP1 common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2 GO:0098869| GSTP1;PTGS2 GO:0032355| response to estradiol stimulus GSTP1;PTGS2 37843:[DB00480 DB03288] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03288|5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide PYGL common genes common pathways 37844:[DB00480 DB05299] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05299|keyhole limpet hemocyanin IL2 common genes common pathways GO:0050728| negative regulation of inflammatory response IL2;CDH5 GO:0007155| cell adhesion CDH5;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;TNFSF11 GO:0008284| positive regulation of cell proliferation IL2;PTGS2 GO:0043066| negative regulation of apoptotic process IL2;PTGS2 GO:0010469| regulation of receptor activity IL2;TNFSF11 GO:0006955| immune response TNFSF11;IL2 37845:[DB00480 DB00611] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 37846:[DB00480 DB03114] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03114|PAS219 SRC common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0070542| response to fatty acid PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0034332| adherens junction organization CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:1902533| TNFSF11;SRC GO:0098609| SRC;CDH5 GO:0071456| cellular response to hypoxia SRC;PTGS2 37847:[DB00480 DB02105] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0007612| learning PTGS2;COMT GO:0042493| response to drug ABCB1;COMT;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;COMT 37848:[DB00480 DB09072] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADHFE1;ALDH5A1 37849:[DB00480 DB03203] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes ABCB1 common pathways GO:0099040| ABCB1 GO:0034332| adherens junction organization CDH5;PVR GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:0007156| homophilic cell adhesion CDH5;PVR GO:1901529| ABCB1 GO:0007155| cell adhesion CDH5;PVR GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 37850:[DB00480 DB13988] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13988|SB-269970 HTR7 common genes common pathways 37851:[DB00480 DB01049] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01049|Ergoloid mesylate DRD1;DRD5;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;CYP3A4 common genes common pathways GO:0007612| learning DRD3;DRD5;PTGS2;DRD1 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11;ADRB2;DRD3 GO:0008284| positive regulation of cell proliferation ADRA2A;ADRA1D;DRD3;HTR2A;PTGS2;HTR1A;HTR2B GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug ADRA1A;DRD2;DRD1;HTR2A;HTR2B;PTGS2;HTR2C;ABCB1;HTR1B;DRD3 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0007568| aging HTR2A;ADRA1A;ADRB3;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0043406| positive regulation of MAP kinase activity HTR2B;HTR2A;ADRA2A;TNFSF11 GO:0007275| multicellular organismal development ADRA1D;TNFSF11;ADRA1B GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0050873| brown fat cell differentiation ADRB2;ADRB3;ADRB1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0007613| memory PTGS2;DRD1;HTR2A GO:0045907| positive regulation of vasoconstriction ADRA1D;ADRA2C;PTGS2;ADRA1B;ADRA1A;HTR2A GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;PTGS2;ADRA1B;ADRA1A GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;ADRA1A 37852:[DB00480 DB04350] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04350|Argadin CHIT1 common genes common pathways GO:0006955| immune response TNFSF11;CHIT1 37853:[DB00480 DB07358] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07358|2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide GCK common genes common pathways 37854:[DB00480 DB11726] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11726|Encenicline CHRNA7 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0007613| memory CHRNA7;PTGS2 37855:[DB00480 DB02908] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02908|RU78783 SRC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| CDH5;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption TNFSF11;SRC 37856:[DB00480 DB01055] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01055|Mimosine SHMT1;CCL2;TYR common genes common pathways GO:0033280| response to vitamin D TYR;PTGS2 GO:0050870| positive regulation of T cell activation CCL2;TNFSF11 GO:0006955| immune response CCL2;TNFSF11 GO:0006954| inflammatory response CCL2;PTGS2 GO:0001525| angiogenesis CCL2;PTGS2 GO:1990830| TNFSF11;SHMT1 GO:0009887| organ morphogenesis CCL2;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;CCL2 GO:0055114| oxidation-reduction process TYR;PTGS2 GO:0002548| monocyte chemotaxis TNFSF11;CCL2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;CCL2 GO:0007155| cell adhesion CCL2;CDH5 37857:[DB00480 DB00745] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;ADRA1B GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2;CYP2C9 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2;CYP1A2 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2B6;CYP1A2;CYP2C19;PTGS2;CYP3A5 GO:0042493| response to drug CYP1A2;ABCB1;SLC6A3;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0007568| aging PTGS2;SLC6A3 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 37858:[DB00480 DB07841] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07841|Geranylgeranyl diphosphate FNTA;PGGT1B;FNTB;GGPS1;FDPS;RABGGTA;RABGGTB common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;FNTB GO:0034097| response to cytokine stimulus PTGS2;PGGT1B GO:0008284| positive regulation of cell proliferation PTGS2;PGGT1B GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FNTA GO:0006629| lipid metabolic process PTGS2;FDPS 37859:[DB00480 DB04657] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04657|Carboxin SDHA common genes common pathways GO:0055114| oxidation-reduction process SDHA;PTGS2 37860:[DB00480 DB00779] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;TDO2 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC22A6 37861:[DB00480 DB01086] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01086|Benzocaine SCN10A;CES1;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0019233| sensory perception of pain SCN10A;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SCN10A;ABCB1 GO:0006810| transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 37862:[DB00480 DB00858] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00858|Drostanolone AR;CYP19A1;SHBG common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0055114| oxidation-reduction process PTGS2;CYP19A1 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0006810| transport AR;ABCB1 37863:[DB00480 DB01562] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 37864:[DB00480 DB08042] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08042|N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0007275| multicellular organismal development TNFSF11;KDR GO:0001525| angiogenesis PTGS2;KDR GO:0030154| cell differentiation TNFSF11;KDR 37865:[DB00480 DB06554] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06554|Gaboxadol SLC36A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC36A1 37866:[DB00480 DB08363] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08363|1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine TP53 common genes common pathways GO:0034644| cellular response to UV PTGS2;TP53 GO:0030154| cell differentiation TNFSF11;TP53 GO:0008285| negative regulation of cell proliferation PTGS2;TP53;CDH5 GO:0014070| response to organic cyclic compound PTGS2;TP53 GO:0043065| positive regulation of apoptotic process TP53;PTGS2 GO:0007275| multicellular organismal development TP53;TNFSF11 GO:0006979| response to oxidative stress TP53;PTGS2 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process TP53;CRBN GO:0034605| cellular response to heat PTGS2;TP53 GO:0007568| aging PTGS2;TP53 GO:0071456| cellular response to hypoxia PTGS2;TP53 GO:0043066| negative regulation of apoptotic process PTGS2;TP53 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TP53;TNFSF11 GO:0034097| response to cytokine stimulus PTGS2;TP53 GO:0010243| response to organic nitrogen PTGS2;TP53 GO:0042493| response to drug ABCB1;PTGS2;TP53 37867:[DB00480 DB02853] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02853|D-Proline SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 37868:[DB00480 DB04275] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04275|N-acetylserotonin SPR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;SPR 37869:[DB00480 DB13875] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13875|Harmaline HNMT common genes common pathways 37870:[DB00480 DB06704] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;PTGS2 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport ABCB1;SLC6A2 37871:[DB00480 DB06226] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06226|Nelipepimut-S HLA-A;HLA-A common genes common pathways GO:0006955| immune response TNFSF11;HLA-A 37872:[DB00480 DB03121] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03121|(1-Benzyl-5-methoxy-2-methyl-1H-indol-3-yl)acetic acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PLA2G2A;PTGS2 37873:[DB00480 DB07757] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07757|(9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TNFSF11 37874:[DB00480 DB04367] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04367|Debromohymenialdisine TNK2;CLK1 common genes common pathways GO:0030154| cell differentiation TNK2;TNFSF11 GO:0042127| regulation of cell proliferation TNK2;PTGS2 37875:[DB00480 DB09322] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09322|Zinc sulfate ALPPL2 common genes common pathways 37876:[DB00480 DB08553] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08553|(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime BRAF common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;BRAF GO:0043066| negative regulation of apoptotic process PTGS2;BRAF GO:0009887| organ morphogenesis TNFSF11;BRAF GO:0030154| cell differentiation BRAF;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation BRAF;PTGS2 37877:[DB00480 DB07544] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07544|N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE BCAT1 common genes common pathways 37878:[DB00480 DB04178] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04178|Di-Stearoyl-3-Sn-Phosphatidylcholine BPI;SLC25A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC25A4 GO:0006810| transport SLC25A4;ABCB1 GO:0006955| immune response TNFSF11;BPI 37879:[DB00480 DB00142] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;TAT GO:0007613| memory GRIN2A;GRIN1;PTGS2 GO:0019722| calcium-mediated signaling GRIN2A;GRIN2B;GRIN2D;TNFSF11;GRIN2C;GRIN1 GO:0051384| response to glucocorticoid stimulus TAT;GOT1;PTGS2 GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0019233| sensory perception of pain GRIN1;GRM1;PTGS2;GRIN2A GO:0001525| angiogenesis PTGS2;ENPEP GO:0071260| cellular response to mechanical stimulus GCLC;PTGS2 GO:0006629| lipid metabolic process SLC16A1;PTGS2 GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;PTGS2 GO:0055085| transmembrane transport SLC16A1;SLC16A10;SLC25A22;ABCB1;GRIK4;SLC1A7;GRIK5;GRIK2;GRIK1;SLC25A18;GRIK3 GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:1990830| TNFSF11;GCLM;BCAT2 GO:0006810| transport GRIN2C;GRIK2;GRIA3;GRIK1;GRID2;GRIK4;ABCB1;GRIN2B;GRIN2A;GRIA4 GO:0007568| aging ABAT;GCLC;GCLM;PTGS2 GO:0006979| response to oxidative stress GCLM;SLC7A11;PTGS2;GCLC;TAT GO:0051260| protein homooligomerization GLUL;TNFSF11;SLC1A1 GO:0055114| oxidation-reduction process ALDH18A1;PTGS2;GLUD1;AASS;GLUD2 GO:0042493| response to drug SLC1A3;SLC1A2;GAD1;PFAS;ABAT;ABCB1;GRIN2A;GCLM;GAD2;PTGS2 GO:0007612| learning GRIN2A;PTGS2;GRIN1 GO:0043066| negative regulation of apoptotic process ASNS;PTGS2;GCLC GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 37880:[DB00480 DB07444] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07444|6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE DAPK1 common genes common pathways GO:0043066| negative regulation of apoptotic process DAPK1;PTGS2 37881:[DB00480 DB00439] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCG2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;HMGCR;PTGS2 GO:0097756| PTGS2;HMGCR GO:0006810| transport ABCB11;ABCG2;ABCC2;ABCB1 GO:0007568| aging PTGS2;HMGCR GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide ABCC2;UGT1A1;PTGS2 GO:1901529| ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2 GO:0055114| oxidation-reduction process HMGCR;PTGS2;CYP2C8;CYP3A7;CYP3A5;CYP3A4;CYP2D6;CYP2B6;CYP2C9 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCC2;ABCB1;ABCG2;UGT1A1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 37882:[DB00480 DB00593] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP3A4;CYP3A43 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055085| transmembrane transport CACNA1G;ABCB1 37883:[DB00480 DB11842] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11842|Angiotensin II AGTR1 common genes common pathways GO:0042127| regulation of cell proliferation AGTR1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0019722| calcium-mediated signaling TNFSF11;AGTR1 37884:[DB00480 DB06594] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP2C9 GO:0042493| response to drug ABCB1;HTR2C;CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 37885:[DB00480 DB00599] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00599|Thiopental GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;FAAH;CHRM3;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0019233| sensory perception of pain CHRNA4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0007613| memory PTGS2;CHRNA7 GO:0042493| response to drug CYP2E1;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport GABRA1;ABCB1;GABRA5;GABRA3;GABRA4;GABRA6;GRIK2 GO:0006979| response to oxidative stress CHRNA4;PTGS2 37886:[DB00480 DB13173] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;IGF2R 37887:[DB00480 DB06680] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06680|Asoprisnil PGR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11 GO:0038001| paracrine signaling PGR;TNFSF11 37888:[DB00480 DB00486] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0007568| aging CNR1;PTGS2 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP2E1;CYP2C9 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0050728| negative regulation of inflammatory response CNR2;CDH5 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CNR1 GO:0007613| memory CNR1;PTGS2 GO:0006954| inflammatory response CNR2;PTGS2 GO:0006955| immune response CNR2;TNFSF11 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain CNR2;PTGS2;CNR1 GO:0043065| positive regulation of apoptotic process CNR1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2C9 37889:[DB00480 DB05120] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05120|AT1391 INSR common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR GO:0009887| organ morphogenesis TNFSF11;INSR GO:0007612| learning PTGS2;INSR GO:0008284| positive regulation of cell proliferation INSR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 GO:0007613| memory PTGS2;INSR 37890:[DB00480 DB09207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0042493| response to drug PTGS2;DRD2;ABCB1;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11;DRD3 GO:0008284| positive regulation of cell proliferation DRD3;PTGS2 GO:0007612| learning PTGS2;DRD3 GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 37891:[DB00480 DB04094] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04094|4-Hydroxy-2-Butanone FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A GO:0019221| cytokine-mediated signaling pathway FKBP1A;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A 37892:[DB00480 DB04719] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04719|DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 37893:[DB00480 DB04462] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04462|Tetrabromo-2-Benzotriazole CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 37894:[DB00480 DB05996] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05996|Glembatumumab vedotin GPNMB common genes common pathways GO:0007155| cell adhesion GPNMB;CDH5 GO:0010469| regulation of receptor activity TNFSF11;GPNMB GO:0030282| bone mineralization GPNMB;PTGS2 GO:0008285| negative regulation of cell proliferation GPNMB;CDH5;PTGS2 37895:[DB00480 DB08015] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08015|(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways 37896:[DB00480 DB04197] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04197|Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0007568| aging PTGS2;ARG1 GO:0032496| response to lipopolysaccharide ARG1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ARG1 GO:0010042| response to manganese ion ARG1;PTGS2 37897:[DB00480 DB13894] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13894|Agkistrodon piscivorus antivenin PLA2G10 common genes common pathways GO:1990830| TNFSF11;PLA2G10 GO:0006629| lipid metabolic process PLA2G10;PTGS2 37898:[DB00480 DB05915] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05915|MYO-029 MSTN common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;MSTN GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;MSTN GO:0051384| response to glucocorticoid stimulus MSTN;PTGS2 37899:[DB00480 DB00304] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 37900:[DB00480 DB03381] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03381|Hexadecanal RHO;DBI common genes common pathways 37901:[DB00480 DB07981] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07981|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS1;PTGS2 37902:[DB00480 DB03048] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03048|6-Carboxymethyluracil DPYD common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DPYD 37903:[DB00480 DB01106] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways GO:0007613| memory PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 37904:[DB00480 DB01210] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0045453| bone resorption ADRB2;TNFSF11 37905:[DB00480 DB02556] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02556|D-Phenylalanine CCBL1;CRH;SLC16A10;SLC7A5 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 GO:0006810| transport ABCB1;SLC7A5 GO:0042493| response to drug ABCB1;CRH;PTGS2 GO:0008284| positive regulation of cell proliferation CRH;PTGS2 GO:0030154| cell differentiation SLC7A5;TNFSF11 GO:0006954| inflammatory response PTGS2;CRH GO:0010942| positive regulation of cell death CRH;PTGS2 GO:0007275| multicellular organismal development TNFSF11;SLC7A5 37906:[DB00480 DB06217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0051260| protein homooligomerization KCND3;TNFSF11;KCNA5 GO:0055085| transmembrane transport ABCB1;KCND3;KCNH2;KCNA5;SCN5A GO:0010033| response to organic substance PTGS2;KCNA5 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 37907:[DB00480 DB02570] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02570|PD150606 CAPNS1 common genes common pathways GO:0008284| positive regulation of cell proliferation CAPNS1;PTGS2 37908:[DB00480 DB07960] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways GO:0006629| lipid metabolic process NEU2;PTGS2 37909:[DB00480 DB02266] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes PTGS2 common pathways GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0019371| cyclooxygenase pathway AKR1C3;PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0010942| positive regulation of cell death AKR1C3;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;PPARA;PPARG GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2;AKR1C3 GO:1990776| PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PPARG;AR;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0055114| oxidation-reduction process PTGS2;PTGS1;AKR1C3 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1;PPARA GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;AKR1C3 GO:0009750| response to fructose stimulus PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0034097| response to cytokine stimulus PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11;PPARA;PPARG GO:0008284| positive regulation of cell proliferation AKR1C3;AR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0030282| bone mineralization PTGS2 GO:0006810| transport TTR;ABCB1;AR GO:0046697| decidualization PTGS2 GO:0007568| aging PTGS2 GO:1902219| PTGS2 GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 37910:[DB00480 DB02377] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0051260| protein homooligomerization GCH1;TNFSF11 GO:0034612| response to tumor necrosis factor GCH1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;GCH1 GO:0042493| response to drug PNP;ABCB1;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0008217| regulation of blood pressure GCH1;PTGS2 GO:0006955| immune response TNFSF11;PNP 37911:[DB00480 DB12305] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0006810| transport ABCB1;SLC6A2 GO:0007568| aging SLC6A3;PTGS2 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;SLC6A2 GO:0042493| response to drug PTGS2;SLC6A2;SLC6A3;SLC6A4;ABCB1 GO:0007613| memory SLC6A4;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 37912:[DB00480 DB01209] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01209|Dezocine OPRM1;OPRK1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0019233| sensory perception of pain OPRM1;OPRK1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 37913:[DB00480 DB01619] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01619|Phenindamine HRH1 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 37914:[DB00480 DB05892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05892|RI 624 NGF common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process NGF;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;NGF GO:0043066| negative regulation of apoptotic process PTGS2;NGF GO:0010469| regulation of receptor activity NGF;TNFSF11 37915:[DB00480 DB07425] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07425|Sobetirome THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TNFSF11 GO:0009887| organ morphogenesis THRB;TNFSF11 37916:[DB00480 DB02942] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02942|Inositol 1,3-Bisphosphate EEA1 common genes common pathways 37917:[DB00480 DB08992] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08992|Eperisone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 37918:[DB00480 DB12752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12752|Bucindolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 37919:[DB00480 DB00973] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes ABCB1 common pathways GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCG8;ABCB1;ABCC2;ABCG5;ABCG2;NPC1L1;UGT1A1;PTGS2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;ABCC2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;ABCG5;SLCO1B1;ABCB11;ABCC2;ABCB1;ABCG8;ABCC3 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0006810| transport ABCC3;ABCC2;ABCB1;ABCB11;ABCG2 GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0007275| multicellular organismal development TNFSF11;ANPEP GO:0001525| angiogenesis ANPEP;PTGS2 GO:0006629| lipid metabolic process CYP3A4;SOAT1;PTGS2;NPC1L1;UGT2B7 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC3;ABCG2;ABCG5 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0008217| regulation of blood pressure ANPEP;PTGS2 GO:0042908| xenobiotic transport ABCB1;ABCC3;ABCG2 GO:0030154| cell differentiation TNFSF11;ANPEP GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0072089| stem cell proliferation ABCB1 37920:[DB00480 DB11723] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11723|Dutogliptin DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 37921:[DB00480 DB04153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04153|S-Hydroxymethyl Glutathione ADH5 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH5 GO:0032496| response to lipopolysaccharide ADH5;PTGS2 37922:[DB00480 DB09330] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0006979| response to oxidative stress EGFR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0032355| response to estradiol stimulus EGFR;PTGS2;CYP1A2 GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0098609| EGFR;CDH5 GO:0006810| transport ABCG2;ABCB1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0008284| positive regulation of cell proliferation EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;TNFSF11 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;ABCG2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP1A2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0014070| response to organic cyclic compound CYP1A2;EGFR;PTGS2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0001503| ossification TNFSF11;EGFR GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PTGS2 GO:0007275| multicellular organismal development EGFR;TNFSF11 37923:[DB00480 DB02161] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02161|Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester CES1;CES1 common genes common pathways 37924:[DB00480 DB05004] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05004|Peptide YY (3-36) NPY2R;NPY1R;NPY5R;NPY4R common genes common pathways GO:0007568| aging NPY2R;NPY5R;PTGS2 GO:0043066| negative regulation of apoptotic process NPY5R;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;NPY5R GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;NPY5R GO:0008217| regulation of blood pressure NPY1R;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;NPY2R GO:0019233| sensory perception of pain PTGS2;NPY1R 37925:[DB00480 DB05740] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0019233| sensory perception of pain CHRNB2;CHRNA4;PTGS2 GO:0007613| memory CHRNB2;PTGS2;CHRNA7 GO:0007612| learning CHRNB2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;CHRNA10 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0006979| response to oxidative stress PTGS2;CHRNA4 37926:[DB00480 DB06670] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06670|Odanacatib CTSK;CYP3A4;CYP2C8;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0045453| bone resorption CTSK;TNFSF11 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGS2 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:1901529| ABCB1 37927:[DB00480 DB03756] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0007566| embryo implantation PTGS2;RXRA GO:0070542| response to fatty acid SREBF1;PTGS2 GO:0014070| response to organic cyclic compound SREBF1;PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;FABP7;PPARG;CDH5 GO:0006629| lipid metabolic process CYP2C9;PPARA;PPARG;PTGS2;SREBF1 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0007568| aging PTGS2;SREBF1 GO:0010033| response to organic substance PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRG;SREBF1;TNFSF11;RXRB;PPARA;RXRA;PPARG GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0042493| response to drug PPARG;ABCB1;PTGS2;SREBF1 GO:0050728| negative regulation of inflammatory response PPARA;CDH5 37928:[DB00480 DB06362] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 37929:[DB00480 DB04768] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04768|Pyrithiamine Pyrophosphate TPK1 common genes common pathways 37930:[DB00480 DB03052] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0001516| prostaglandin biosynthetic process TBXAS1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;TBXAS1 GO:0019371| cyclooxygenase pathway PTGS2;TBXAS1 GO:0006693| prostaglandin metabolic process PTGS2;TBXAS1 GO:0006629| lipid metabolic process TBXAS1;PTGS2 GO:0006631| fatty acid metabolic process TBXAS1;PTGS2 GO:0055114| oxidation-reduction process TBXAS1;PTGS2 37931:[DB00480 DB05241] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05241|XL765 PIK3CA;PIK3CG;PIK3CD;PIK3CB;MTOR common genes common pathways GO:0007155| cell adhesion PIK3CB;CDH5 GO:0007156| homophilic cell adhesion CDH5;PIK3CB GO:0048661| positive regulation of smooth muscle cell proliferation MTOR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CA;PIK3CB;PIK3CD;TNFSF11;MTOR;PIK3CG GO:0045670| regulation of osteoclast differentiation TNFSF11;MTOR GO:0071456| cellular response to hypoxia MTOR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process MTOR;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;PIK3CG GO:0001525| angiogenesis PIK3CG;PIK3CA;PTGS2 GO:0006954| inflammatory response PIK3CA;PTGS2;PIK3CB;PIK3CD;PIK3CG GO:0010942| positive regulation of cell death PTGS2;MTOR GO:0030154| cell differentiation PIK3CD;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation PIK3CA;PTGS2 37932:[DB00480 DB00473] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways GO:0019233| sensory perception of pain PTGS2;SCN10A GO:0055085| transmembrane transport SCN5A;SCN10A;ABCB1 37933:[DB00480 DB02467] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02467|L-methionine (S)-S-oxide RAB5A;thyA common genes common pathways 37934:[DB00480 DB08103] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08103|2,6-dibromo-4-phenoxyphenol TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport TTR;ABCB1 37935:[DB00480 DB03147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0014070| response to organic cyclic compound NQO1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYB5R3;ACADM;ACAD8;FDXR;ACOX1;ACADS;CYB5R1 GO:0006693| prostaglandin metabolic process ACOX1;PTGS2 GO:0042307| positive regulation of protein import into nucleus TPR;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;AIFM1 GO:0010942| positive regulation of cell death PTGS2;AIFM1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;POR GO:0098869| PTGS2;TXNRD1;GSR GO:0006979| response to oxidative stress NQO1;PTGS2 GO:0007568| aging NQO1;DLD;PTGS2 GO:0034605| cellular response to heat TPR;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;GFER GO:0032355| response to estradiol stimulus NQO1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;POR;NQO1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NOS1 GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0055114| oxidation-reduction process GCDH;ERO1B;ACADM;MAOB;ACAD8;XDH;NDUFA9;DAO;IL4I1;PTGS2;MAOA;CYB5R3;CYB5R1;POR;GFER;TXNRD1;AIFM1;GSR;IVD;FDXR;NQO2;ACOX1;NOS1;NQO1;DPYD;ACADS;DLD GO:0006631| fatty acid metabolic process ACADS;ACOX1;PTGS2;ACADM GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0042493| response to drug PTGS2;MAOB;ABCB1;POR 37936:[DB00480 DB03485] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03485|Alpha-D-Fucose LTF common genes common pathways GO:0043066| negative regulation of apoptotic process LTF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;TNFSF11 GO:0001503| ossification TNFSF11;LTF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;LTF 37937:[DB00480 DB00540] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB3;ADRB2 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1;CYP3A4;CYP1A2;CYP2D6 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response HRH1;ORM1;PTGS1;PTGS2 GO:0007613| memory SLC6A4;HRH1;PTGS2;HTR2A GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA2C;HRH1;ADRA1D;ADRA1A;HTR2A;ADRA1B;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;ADRA1A GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D;CHRM3 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2;DRD2 GO:0008284| positive regulation of cell proliferation ADRA2A;ADRA1D;CHRM1;HTR2A;HTR1A;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP3A5;PTGS1;CYP2E1;CYP3A4;CYP2D6;CYP1A2 GO:0042493| response to drug DRD2;ADRA1A;CYP2E1;HTR2A;SLC6A2;PTGS2;HTR2C;CYP1A2;ABCB1;SLC6A4 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0007568| aging PTGS2;HTR2A;ADRB3;ADRA1A GO:0006810| transport SLC6A2;ABCB1 GO:0032355| response to estradiol stimulus SLC6A4;CYP1A2;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0098869| PTGS1;ALB;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2A GO:0010033| response to organic substance PTGS2;SLC6A4;CYP1A2 37938:[DB00480 DB03710] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03710|N5-(1-Imino-3-Butenyl)-L-Ornithine NOS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;TNFSF11 37939:[DB00480 DB14562] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14562|Andexanet alfa TFPI common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;TFPI GO:0032355| response to estradiol stimulus PTGS2;TFPI 37940:[DB00480 DB05252] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05252|Fenoxaprop-ethyl NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0055114| oxidation-reduction process NOS2;PTGS2 37941:[DB00480 DB03701] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03701|Vanoxerine SLC6A3;CYP3A4 common genes common pathways GO:0055085| transmembrane transport SLC6A3;ABCB1 GO:0007568| aging SLC6A3;PTGS2 GO:0042493| response to drug PTGS2;SLC6A3;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 37942:[DB00480 DB07168] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07168|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile CAMK2B common genes common pathways GO:0030154| cell differentiation TNFSF11;CAMK2B GO:0007275| multicellular organismal development CAMK2B;TNFSF11 37943:[DB00480 DB07276] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07276|5-CYANO-N-(2,5-DIMETHOXYBENZYL)-6-ETHOXYPYRIDINE-2-CARBOXAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0043065| positive regulation of apoptotic process MAPK8;PTGS2 GO:0071260| cellular response to mechanical stimulus MAPK8;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;MAPK8;MAPK8IP1 37944:[DB00480 DB01927] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01927|Duroquinone NQO1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;NQO1 GO:0055114| oxidation-reduction process PTGS2;NQO1 GO:0006979| response to oxidative stress NQO1;PTGS2 GO:0032355| response to estradiol stimulus NQO1;PTGS2 GO:0007568| aging NQO1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;NQO1 37945:[DB00480 DB08995] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08995|Diosmin AHR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AHR 37946:[DB00480 DB01390] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways GO:0006810| transport ABCB1;SLC4A4 GO:0055085| transmembrane transport SLC4A4;SLC4A7;SLC4A8;ABCB1 37947:[DB00480 DB06717] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS2 37948:[DB00480 DB01851] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01851|Tetrabutylammonium Ion IGKC common genes common pathways GO:0006955| immune response TNFSF11;IGKC 37949:[DB00480 DB02545] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02545|Fexaramine NR1H4 common genes common pathways GO:0006954| inflammatory response PTGS2;NR1H4 GO:0050728| negative regulation of inflammatory response CDH5;NR1H4 GO:0043066| negative regulation of apoptotic process NR1H4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1H4 GO:0007043| cell-cell junction assembly CDH5;NR1H4 37950:[DB00480 DB03619] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0006954| inflammatory response PTGS2;NR1H4 GO:0050728| negative regulation of inflammatory response NR1H4;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1H4 GO:0043066| negative regulation of apoptotic process NR1H4;GSTP1;PTGS2 GO:0055085| transmembrane transport SLC10A2;SLC10A1;ABCB1;ABCB11;SLCO1A2 GO:0007043| cell-cell junction assembly NR1H4;CDH5 GO:0098869| GSTP1;PTGS2 GO:0006810| transport ABCB11;ABCB1;SLC10A2;SLC10A1 GO:0032355| response to estradiol stimulus GSTP1;PTGS2 37951:[DB00480 DB06374] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06374|Elacestrant ESR1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 37952:[DB00480 DB06082] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06082|PX-478 HIF1A common genes common pathways GO:0071456| cellular response to hypoxia HIF1A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HIF1A;TNFSF11 GO:0043066| negative regulation of apoptotic process HIF1A;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;HIF1A GO:0016567| protein ubiquitination HIF1A;CRBN GO:0030154| cell differentiation HIF1A;TNFSF11 GO:0001525| angiogenesis HIF1A;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;HIF1A 37953:[DB00480 DB01723] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01723|{3-[3-(3,4-Dimethoxy-Phenyl)-1-(1-{1-[2-(3,4,5-Trimethoxy-Phenyl)-Butyryl]-Piperidin-2yl}-Vinyloxy)-Propyl]-Phenoxy}-Acetic Acid FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TNFSF11 GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CDH5 37954:[DB00480 DB02727] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02727|N-Butyl-N'-Hydroxyguanidine NOS1 common genes common pathways GO:0055114| oxidation-reduction process NOS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NOS1 37955:[DB00480 DB01407] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;ADRB2;TNFSF11 GO:0043066| negative regulation of apoptotic process NGF;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0042493| response to drug ABCB1;PTGS2;CYP1A1 GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0010469| regulation of receptor activity NGF;TNF;TNFSF11 GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0007568| aging PTGS2;CYP1A1;ADRB3 GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0010033| response to organic substance CYP1A1;PTGS2;TNF GO:0043065| positive regulation of apoptotic process PTGS2;NGF;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050873| brown fat cell differentiation ADRB2;ADRB3;ADRB1;PTGS2 GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0006954| inflammatory response TNF;PTGS2 GO:0006955| immune response TNFSF11;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;NGF GO:0045453| bone resorption TNFSF11;ADRB2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 37956:[DB00480 DB01439] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11;OPRD1 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0019233| sensory perception of pain OPRK1;OPRM1;PTGS2;OPRD1 37957:[DB00480 DB11324] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11324|Nonivamide TRPV1 common genes common pathways GO:0071318| cellular response to ATP PTGS2;TRPV1 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0034605| cellular response to heat PTGS2;TRPV1 GO:0006810| transport TRPV1;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TRPV1 GO:0055085| transmembrane transport TRPV1;ABCB1 GO:0019233| sensory perception of pain PTGS2;TRPV1 GO:0043065| positive regulation of apoptotic process PTGS2;TRPV1 GO:0006629| lipid metabolic process PTGS2;TRPV1 GO:0006954| inflammatory response PTGS2;TRPV1 37958:[DB00480 DB07497] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07497|5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL PC common genes common pathways GO:0006629| lipid metabolic process PC;PTGS2 37959:[DB00480 DB05737] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05737|Varespladib methyl PLA2G2A;PLA2G10 common genes common pathways GO:1990830| TNFSF11;PLA2G10 GO:0006629| lipid metabolic process PTGS2;PLA2G10;PLA2G2A 37960:[DB00480 DB03379] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03379|2-Carboxyethylphosphonic Acid TPI1 common genes common pathways GO:0007275| multicellular organismal development TPI1;TNFSF11 37961:[DB00480 DB07707] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07707|(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TNFSF11;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 37962:[DB00480 DB01411] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0042493| response to drug PTGS2;ABCC2;ABCB1 GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP2C9;CYP3A4 GO:0050728| negative regulation of inflammatory response CDH5;NFKB1 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2 GO:0019221| cytokine-mediated signaling pathway IL5;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0032496| response to lipopolysaccharide ABCC2;PTGS2 GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;IL5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;NFKB1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;NFKB1 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0010033| response to organic substance TNF;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0010469| regulation of receptor activity TNF;IL5;TNFSF11 GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0006810| transport ABCC2;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;NFKB1;TNFSF11 GO:0006954| inflammatory response TNF;IL5;PTGS2;NFKB1 GO:0006955| immune response TNF;IL5;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;IL5;TNFSF11 GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0043065| positive regulation of apoptotic process TNF;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF 37963:[DB00480 DB13146] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes ABCB1 common pathways GO:0014070| response to organic cyclic compound PTGS2;ABCC4 GO:0006855| drug transmembrane transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0019722| calcium-mediated signaling GRIN2C;GRIN1;GRIN2A;GRIN2B;TNFSF11;GRIN2D GO:0045332| phospholipid translocation ABCB1 GO:0007613| memory GRIN1;PTGS2;GRIN2A GO:0042908| xenobiotic transport ABCB1 GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0019233| sensory perception of pain GRIN1;PTGS2;GRIN2A GO:0043065| positive regulation of apoptotic process GRIN2A;GRIN1;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCC4 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance ABCC4;PTGS2 GO:0006810| transport GRIN2A;GRIN2B;ABCB1;GRIA4;GRIA3;GRIN2C;SLC7A7 GO:0042493| response to drug ABCB1;GRIN2A;ABCC4;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process ABCC4;PTGS2 GO:0099040| ABCB1 GO:0010243| response to organic nitrogen ABCC4;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2 GO:1901529| ABCB1 GO:0007612| learning GRIN1;PTGS2;GRIN2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 37964:[DB00480 DB09555] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0006954| inflammatory response PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory PTGS2;HRH1 GO:0006855| drug transmembrane transport SLC22A2;SLC22A1;ABCB1 37965:[DB00480 DB08346] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08346|(5Z)-13-CHLORO-14,16-DIHYDROXY-3,4,7,8,9,10-HEXAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,11(12H)-DIONE HSP90AB1 common genes common pathways GO:0042493| response to drug ABCB1;HSP90AB1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HSP90AB1 GO:0010033| response to organic substance PTGS2;HSP90AB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HSP90AB1 37966:[DB00480 DB07678] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07678|(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL ESR1;NCOA2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11;NCOA2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 37967:[DB00480 DB02169] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02169|9,10-Deepithio-9,10-Didehydroacanthifolicin PPP1CC common genes common pathways 37968:[DB00480 DB05790] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05790|SR 140333 TACR1 common genes common pathways GO:0006954| inflammatory response PTGS2;TACR1 GO:0019233| sensory perception of pain PTGS2;TACR1 GO:0008217| regulation of blood pressure PTGS2;TACR1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TACR1 GO:0014070| response to organic cyclic compound PTGS2;TACR1 GO:0045907| positive regulation of vasoconstriction PTGS2;TACR1 GO:0032355| response to estradiol stimulus PTGS2;TACR1 37969:[DB00480 DB01429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0006954| inflammatory response PTGS2;ORM1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0055085| transmembrane transport SCN5A;CALM1;ABCB1 37970:[DB00480 DB03892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03892|5-N-Allyl-Arginine NOS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS1 GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;TNFSF11 37971:[DB00480 DB08080] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08080|LATRUNCULIN B ACTA1;MKL1;SPIRE2 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MKL1 37972:[DB00480 DB00379] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0055085| transmembrane transport ABCB1;SCN5A GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP2B6;CYP2D6;CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;CYP2E1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AHR GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 37973:[DB00480 DB07315] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07315|5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide PYGL common genes common pathways 37974:[DB00480 DB04636] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04636|Glutamine t-butyl ester QPCT common genes common pathways 37975:[DB00480 DB04676] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04676|Dansyllysine IGHA2 common genes common pathways GO:0006955| immune response IGHA2;TNFSF11 37976:[DB00480 DB07082] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07082|1,1,1,3,3,3-HEXAFLUORO-2-{4-[(2,2,2-TRIFLUOROETHYL)AMINO]PHENYL}PROPAN-2-OL NR1H2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1H2 37977:[DB00480 DB03276] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03276|4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid GRB2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;GRB2 GO:0042127| regulation of cell proliferation GRB2;PTGS2 GO:0007568| aging GRB2;PTGS2 GO:0030154| cell differentiation TNFSF11;GRB2 37978:[DB00480 DB01127] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP19A1;CYP3A4 GO:0042493| response to drug CYP2E1;PTGS2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0042908| xenobiotic transport ABCB1;NR1I2 37979:[DB00480 DB12952] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12952|Methylprednisone CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 37980:[DB00480 DB02552] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;FDPS 37981:[DB00480 DB08699] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways GO:0030154| cell differentiation CAMK2G;TNFSF11 GO:0007275| multicellular organismal development CAMK2G;TNFSF11 37982:[DB00480 DB07916] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07916|3-{6-[(8-HYDROXY-QUINOLINE-2-CARBONYL)-AMINO]-2-THIOPHEN-2-YL-HEXANOYLAMINO}-4-OXO-BUTYRI ACID CASP1 common genes common pathways GO:0032496| response to lipopolysaccharide CASP1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;TNFSF11 GO:0071260| cellular response to mechanical stimulus CASP1;PTGS2 GO:0050727| regulation of inflammatory response CASP1;PTGS2 37983:[DB00480 DB03800] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways GO:0007568| aging PTGS2;TYMS GO:0042493| response to drug PTGS2;TYMS;ABCB1 GO:0034097| response to cytokine stimulus TYMS;PTGS2 GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 37984:[DB00480 DB03956] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03956|Inositol 2,4,5-trisphosphate PLCD1 common genes common pathways GO:0001525| angiogenesis PLCD1;PTGS2 GO:0006629| lipid metabolic process PTGS2;PLCD1 GO:0042127| regulation of cell proliferation PTGS2;PLCD1 37985:[DB00480 DB02673] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02673|(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 37986:[DB00480 DB07356] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07356|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 37987:[DB00480 DB00697] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00697|Tizanidine ADRA2A;ADRA2B;ADRA2C;NISCH;CYP1A2 common genes common pathways GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0045907| positive regulation of vasoconstriction ADRA2C;PTGS2 GO:0008217| regulation of blood pressure NISCH;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 37988:[DB00480 DB05052] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05052|MF101 ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2 37989:[DB00480 DB06243] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06243|Eflornithine ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation ODC1;PTGS2 37990:[DB00480 DB00195] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB2 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 37991:[DB00480 DB03032] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03032|S-Octylglutathione GSTM4 common genes common pathways 37992:[DB00480 DB03628] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03628|ISO24 SRC common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0070542| response to fatty acid SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0034332| adherens junction organization SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:1902533| TNFSF11;SRC GO:0098609| SRC;CDH5 GO:0071456| cellular response to hypoxia SRC;PTGS2 37993:[DB00480 DB04789] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways GO:0042493| response to drug ABCB1;ABCC2;PTGS2 GO:0032496| response to lipopolysaccharide ABCC2;PTGS2 GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0006810| transport ABCC2;ABCB1 GO:0006855| drug transmembrane transport ABCC2;ABCB1 37994:[DB00480 DB07893] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07893|PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE IGKC common genes common pathways GO:0006955| immune response TNFSF11;IGKC 37995:[DB00480 DB02979] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02979|N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane NOS3 common genes common pathways GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;NOS3;CDH5 GO:0001525| angiogenesis PTGS2;NOS3 37996:[DB00480 DB01452] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01452|Diamorphine OPRM1;OPRK1;OPRD1;CES1 common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;OPRK1 GO:0006955| immune response OPRD1;TNFSF11;OPRK1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 37997:[DB00480 DB01363] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA2C GO:0045453| bone resorption ADRB2;TNFSF11 GO:0007613| memory PTGS2;SLC6A4 GO:0006855| drug transmembrane transport ABCB1;SLC18A1 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB3;ADRB2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0006810| transport ABCB1;SLC6A2 GO:0007568| aging ADRB3;SLC6A3;PTGS2 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0055085| transmembrane transport SLC6A3;SLC18A2;SLC18A1;SLC6A2;SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;MAOA;MAOB GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug ABCB1;SLC6A4;SLC6A2;PTGS2;SLC6A3;MAOB 37998:[DB00480 DB06933] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06933|N-(tert-butyl)-4-[5-(pyridin-2-ylamino)quinolin-3-yl]benzenesulfonamide MAPK10 common genes common pathways 37999:[DB00480 DB04540] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04540|Cholesterol RORA;NR1I3;VDR;CLEC4E;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0071456| cellular response to hypoxia RORA;PTGS2 GO:0006810| transport ABCG2;ABCB1 GO:0046697| decidualization VDR;PTGS2 GO:0009887| organ morphogenesis TNFSF11;VDR GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;VDR;TNFSF11;RORA GO:1901529| ABCB1 GO:0050728| negative regulation of inflammatory response RORA;CDH5 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;VDR GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0001525| angiogenesis PTGS2;RORA GO:0007275| multicellular organismal development VDR;TNFSF11 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;RORA GO:0006955| immune response TNFSF11;CLEC4E 38000:[DB00480 DB02381] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02381|nor-NOHA ARG1 common genes common pathways GO:0032496| response to lipopolysaccharide ARG1;PTGS2 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ARG1 GO:0007568| aging ARG1;PTGS2 38001:[DB00480 DB14540] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0032355| response to estradiol stimulus PTGS2;ANXA1 GO:0098609| CDH5;ANXA1 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2;SLCO1A2;SLC22A8 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation ANXA1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 GO:0043066| negative regulation of apoptotic process PTGS2;ANXA1 GO:0042493| response to drug ABCB1;HSD11B2;ANXA1;ABCG2;PTGS2 GO:0002548| monocyte chemotaxis ANXA1;TNFSF11 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process HSD11B2;CYP3A4;CYP11B1;CYP3A7;HSD3B1;CYP3A5;CYP11B2;PTGS2;CYP2C8 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;ANXA1;HSD11B2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0014070| response to organic cyclic compound PTGS2;ANXA1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0031394| positive regulation of prostaglandin biosynthetic process ANXA1;PTGS2 GO:0008217| regulation of blood pressure CYP11B1;PTGS2 GO:0043065| positive regulation of apoptotic process ANXA1;PTGS2 GO:0050727| regulation of inflammatory response ANXA1;PTGS2 GO:0006629| lipid metabolic process CYP11B1;PTGS2;CYP11B2;CYP3A4 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ANXA1 GO:0006954| inflammatory response ANXA1;PTGS2 GO:0006955| immune response TNFSF11;CYP11B1 38002:[DB00480 DB01369] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38003:[DB00480 DB00474] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;PTGS2 GO:0006810| transport GABRA1;ABCB1 38004:[DB00480 DB05301] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05301|LAX-101 PLD1;CASP1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;TNFSF11 GO:0050727| regulation of inflammatory response CASP1;PTGS2 GO:0006629| lipid metabolic process PLD1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0032496| response to lipopolysaccharide PTGS2;CASP1 38005:[DB00480 DB00557] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00557|Hydroxyzine HRH1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006954| inflammatory response HRH1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 38006:[DB00480 DB01351] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0019233| sensory perception of pain CHRNA4;PTGS2 GO:0007613| memory CHRNA7;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0055114| oxidation-reduction process CYP2A6;PTGS2 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0006810| transport GABRA5;GABRA3;GRIK2;GABRA6;GABRA4;GABRA1;ABCB1 GO:0055085| transmembrane transport GRIK2;ABCB1 38007:[DB00480 DB07421] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07421|4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile AR common genes common pathways GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0006810| transport ABCB1;AR 38008:[DB00480 DB03088] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03088|Pidolic Acid VEGFA;AMY2A;IGLC1;TFF2;cycA;ADAM28;KRTAP5-2;HCRT;CCL8;AMY2B;ANG;AMY1A;AMY2A common genes common pathways GO:0002548| monocyte chemotaxis TNFSF11;CCL8 GO:0034332| adherens junction organization ANG;CDH5 GO:0060749| mammary gland alveolus development VEGFA;TNFSF11 GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VEGFA GO:0043066| negative regulation of apoptotic process VEGFA;PTGS2 GO:0043406| positive regulation of MAP kinase activity VEGFA;TNFSF11 GO:0071456| cellular response to hypoxia VEGFA;PTGS2 GO:0010469| regulation of receptor activity CCL8;TNFSF11;HCRT;VEGFA GO:0006954| inflammatory response PTGS2;CCL8 GO:0006955| immune response IGLC1;TNFSF11;CCL8 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;ANG;VEGFA GO:0001525| angiogenesis PTGS2;ANG;VEGFA GO:0007275| multicellular organismal development TNFSF11;ANG;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA GO:0030154| cell differentiation TNFSF11;ANG;VEGFA 38009:[DB00480 DB08173] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08173|5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 38010:[DB00480 DB05509] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05509|LI-301 OPRM1;HTR1A common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0019233| sensory perception of pain PTGS2;OPRM1 GO:0009314| response to radiation PTGS2;OPRM1 38011:[DB00480 DB13872] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0006810| transport GABRA1;GABRG2;ABCB1;GABRA5;GABRA3 38012:[DB00480 DB04741] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04741|Myxothiazol UQCRC1 common genes common pathways GO:0055114| oxidation-reduction process UQCRC1;PTGS2 38013:[DB00480 DB14503] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;TNFSF11 GO:0001503| ossification SLC34A1;TNFSF11 GO:0055085| transmembrane transport SLC20A2;SLC34A2;SLC20A1;SLC34A3;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;SLC34A1 GO:0006810| transport ABCB1;SLC20A1;SLC20A2 GO:0051260| protein homooligomerization SLC34A1;TNFSF11 GO:0042493| response to drug PTGS2;SLC34A1;ABCB1 38014:[DB00480 DB05984] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05984|RAF-265 KDR;BRAF common genes common pathways GO:0009887| organ morphogenesis BRAF;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process KDR;PTGS2;BRAF GO:0042127| regulation of cell proliferation BRAF;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BRAF GO:0030154| cell differentiation BRAF;TNFSF11;KDR GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0001525| angiogenesis KDR;PTGS2 GO:0007275| multicellular organismal development TNFSF11;KDR 38015:[DB00480 DB02029] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02029|N-Cyclohexyl-N'-(4-Iodophenyl)Urea EPHX2 common genes common pathways GO:0008217| regulation of blood pressure EPHX2;PTGS2 GO:0006629| lipid metabolic process EPHX2;PTGS2 GO:0006954| inflammatory response PTGS2;EPHX2 38016:[DB00480 DB11601] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11601|Tuberculin Purified Protein Derivative TLR2 common genes common pathways GO:0070542| response to fatty acid TLR2;PTGS2 GO:0008285| negative regulation of cell proliferation TLR2;PTGS2;CDH5 GO:0006955| immune response TLR2;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR2;TNFSF11 GO:0006954| inflammatory response TLR2;PTGS2 GO:0007612| learning TLR2;PTGS2 GO:0032496| response to lipopolysaccharide TLR2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TLR2 38017:[DB00480 DB03896] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03896|Triphosphoric acid PAPOLA common genes common pathways 38018:[DB00480 DB06190] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06190|Solabegron ADRB3 common genes common pathways GO:0007568| aging PTGS2;ADRB3 GO:0050873| brown fat cell differentiation ADRB3;PTGS2 38019:[DB00480 DB06787] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 38020:[DB00480 DB03860] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03860|N-Butyl-11-[(7r,8r,9s,13s,14s,17s)-3,17-Dihydroxy-13-Methyl-7,8,9,11,12,13,14,15,16,17-Decahydro-6h-Cyclopenta[a]Phenanthren-7-Yl]-N-Methylundecanamide ESR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;TNFSF11 38021:[DB00480 DB06652] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9 GO:0006954| inflammatory response PTGS2;CCR5 GO:0006955| immune response CCR5;TNFSF11 GO:0019722| calcium-mediated signaling TNFSF11;CCR5 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;PTGS2;CYP3A5 38022:[DB00480 DB06412] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0006629| lipid metabolic process PTGS2;SRD5A1;CYP3A4;CYP2D6 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0030154| cell differentiation TNFSF11;SRD5A1 GO:0014070| response to organic cyclic compound PTGS2;SRD5A1 GO:0008217| regulation of blood pressure PTGS2;NPPB GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0055114| oxidation-reduction process MAOA;PTGS2;CYP3A5;SRD5A1;CYP3A7;CYP3A43;CYP3A4;CYP2D6 GO:0042493| response to drug ABCB1;PTGS2;SRD5A1 GO:0006810| transport ABCB1;AR GO:0010469| regulation of receptor activity TNFSF11;NPPB GO:0032355| response to estradiol stimulus PTGS2;SRD5A1 GO:0098869| ALB;PTGS2 38023:[DB00480 DB01228] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0055085| transmembrane transport SCN5A;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 38024:[DB00480 DB01651] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01651|Methyl 4,6-O-[(1r)-1-Carboxyethylidene]-Beta-D-Galactopyranoside APCS common genes common pathways 38025:[DB00480 DB02559] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02559|6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 38026:[DB00480 DB00604] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging HTR2A;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP2B6;CYP3A4;CYP2A6;CYP3A5;CYP3A7;CYP2C8;CYP2C19;PTGS2 GO:0042493| response to drug HTR2A;PTGS2;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0007613| memory PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6;CYP2C9 38027:[DB00480 DB02222] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02222|2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine PNP common genes common pathways GO:0006955| immune response PNP;TNFSF11 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0042493| response to drug PTGS2;ABCB1;PNP 38028:[DB00480 DB07111] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07111|(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid PPARG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0010033| response to organic substance PPARG;PTGS2 38029:[DB00480 DB00707] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00707|Porfimer sodium LDLR;FCGR1A common genes common pathways GO:0006955| immune response FCGR1A;TNFSF11 GO:0006629| lipid metabolic process LDLR;PTGS2 38030:[DB00480 DB06241] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06241|Clenoliximab CD4 common genes common pathways GO:0006955| immune response CD4;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CD4 GO:0033280| response to vitamin D PTGS2;CD4 GO:0050870| positive regulation of T cell activation TNFSF11;CD4 GO:0007155| cell adhesion CDH5;CD4 GO:0032355| response to estradiol stimulus PTGS2;CD4 38031:[DB00480 DB03135] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03135|[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid TPI1 common genes common pathways GO:0007275| multicellular organismal development TPI1;TNFSF11 38032:[DB00480 DB06713] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0098869| ALB;PTGS2 GO:0006810| transport ABCB1;AR GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0006629| lipid metabolic process PTGS2;CYP3A4;STS GO:0038001| paracrine signaling PGR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 38033:[DB00480 DB02126] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02126|4-Carboxycinnamic Acid HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;PTGS2 GO:0098869| HBB;PTGS2;HBA1 GO:0008217| regulation of blood pressure PTGS2;HBB GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB 38034:[DB00480 DB01252] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process UGT2B7;PTGS2;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0007613| memory PTGS2;ABCC8 GO:0042493| response to drug PTGS2;ABCC8;ABCB1;PPARG GO:0032496| response to lipopolysaccharide PTGS2;ABCC8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0055085| transmembrane transport ABCB1;ABCC8 GO:0010033| response to organic substance PTGS2;PPARG 38035:[DB00480 DB08214] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08214|4-(1H-IMIDAZOL-1-YL)PHENOL NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;PTGS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 38036:[DB00480 DB01059] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;PTGS2;CYP1A1;CYP3A5;CYP3A7 GO:0042493| response to drug CYP1A1;PTGS2;CYP1A2;ABCB1 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0055085| transmembrane transport ABCB1;SLC22A5;SLC22A6 GO:0010033| response to organic substance PTGS2;CYP1A1;CYP1A2 GO:0007568| aging PTGS2;CYP1A1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2 GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1;CYP1A2 38037:[DB00480 DB02779] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02779|Dodecane-Trimethylamine PTPN11 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade PTPN11;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTPN11;PTGS2 GO:0006629| lipid metabolic process PTGS2;PTPN11 38038:[DB00480 DB08555] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08555|1-(3-bromophenyl)-7-chloro-6-methoxy-3,4-dihydroisoquinoline MAPK10 common genes common pathways 38039:[DB00480 DB08495] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08495|4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 38040:[DB00480 DB05303] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0006954| inflammatory response PTGS2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;TNFSF11 GO:0006955| immune response IL1R1;TNF;TNFSF11 GO:0050727| regulation of inflammatory response IL1R1;TNF;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0043065| positive regulation of apoptotic process TNF;PTGS2 GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0019221| cytokine-mediated signaling pathway IL1R1;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TNF GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0009887| organ morphogenesis TNFSF11;TNF GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 38041:[DB00480 DB07171] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07171|5-(2-hydroxyethyl)nonane-1,9-diol ECE1 common genes common pathways 38042:[DB00480 DB00002] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0010469| regulation of receptor activity FCGR2B;TNFSF11 GO:0098609| EGFR;CDH5 GO:0006979| response to oxidative stress PTGS2;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0046330| positive regulation of JNK cascade TNFSF11;FCGR2B GO:0042127| regulation of cell proliferation PTGS2;EGFR GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;EGFR GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0001503| ossification EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0006954| inflammatory response FCGR2B;PTGS2 GO:0006955| immune response FCGR3B;C1R;TNFSF11;FCGR1A;C1QC;FCGR3A;FCGR2C;FCGR2B 38043:[DB00480 DB02701] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 GO:0008284| positive regulation of cell proliferation BST1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;TNFSF11 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2;LDHA;CYP2E1 GO:0042493| response to drug CYP2E1;PTGS2;LDHA;ABCB1 GO:0014070| response to organic cyclic compound LDHA;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0043065| positive regulation of apoptotic process LDHA;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;BST1 38044:[DB00480 DB09146] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09146|Iron saccharate HBA1;TF common genes common pathways GO:0098869| HBA1;PTGS2 GO:0010942| positive regulation of cell death PTGS2;HBA1 38045:[DB00480 DB09449] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0042493| response to drug PTGS2;SLC34A1;ABCB1 GO:0055085| transmembrane transport SLC20A1;SLC20A2;SLC34A2;SLC34A3;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;SLC34A1 GO:0006810| transport ABCB1;SLC20A1;SLC20A2 GO:0051260| protein homooligomerization TNFSF11;SLC34A1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;SLC20A1 GO:0001503| ossification TNFSF11;SLC34A1 38046:[DB00480 DB05428] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05428|motexafin gadolinium TXNRD1;TXNRD2;RRM2 common genes common pathways GO:0098869| PTGS2;TXNRD2;TXNRD1 GO:0055114| oxidation-reduction process RRM2;TXNRD1;TXNRD2;PTGS2 38047:[DB00480 DB00083] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways GO:0001525| angiogenesis PTGS2;RHOB GO:0007275| multicellular organismal development RHOB;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;RHOB GO:0030154| cell differentiation RHOB;TNFSF11 GO:0007155| cell adhesion RHOB;CDH5 GO:0045786| negative regulation of cell cycle RHOB;PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2;SNAP25 38048:[DB00480 DB02201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02201|Malonate Ion aroH;SDF2 common genes common pathways 38049:[DB00480 DB07146] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07146|2,3-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-B]PYRIDIN-4-AMINE LCK common genes common pathways GO:0042127| regulation of cell proliferation LCK;PTGS2 GO:0042493| response to drug LCK;PTGS2;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;LCK GO:0050870| positive regulation of T cell activation LCK;TNFSF11 38050:[DB00480 DB07975] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07975|2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0042493| response to drug DHODH;PTGS2;ABCB1 GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 38051:[DB00480 DB04739] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04739|4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE SRC common genes common pathways GO:0070542| response to fatty acid SRC;PTGS2 GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug SRC;PTGS2;ABCB1 38052:[DB00480 DB13775] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13775|Tertatolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;PTGS2 38053:[DB00480 DB08213] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08213|1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE CASP3 common genes common pathways GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2 GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0010033| response to organic substance PTGS2;CASP3 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;PTGS2 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CASP3 GO:0042493| response to drug ABCB1;PTGS2;CASP3 38054:[DB00480 DB09200] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09200|Rivoglitazone CYP3A4;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP3A4 38055:[DB00480 DB13950] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13950|WIN 55212-2 CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 38056:[DB00480 DB02034] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02034|Tridolgosir MAN2A1 common genes common pathways 38057:[DB00480 DB01126] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process SRD5A2;PTGS2;SRD5A1;CYP3A4 GO:0014070| response to organic cyclic compound SRD5A1;SRD5A2;PTGS2 GO:0030154| cell differentiation TNFSF11;SRD5A2;SRD5A1 GO:0055114| oxidation-reduction process SRD5A1;PTGS2;SRD5A2;CYP3A4 GO:0042493| response to drug SRD5A2;PTGS2;SRD5A1;ABCB1 GO:0010033| response to organic substance PTGS2;SRD5A2 GO:0032355| response to estradiol stimulus SRD5A1;PTGS2 38058:[DB00480 DB06370] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP3A4;CYP2D6;CYP2C9 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 38059:[DB00480 DB03693] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03693|N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide CSNK1G2 common genes common pathways 38060:[DB00480 DB05041] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05041|RP101 UPP1;UPP2 common genes common pathways 38061:[DB00480 DB13866] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13866|Etynodiol CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38062:[DB00480 DB02624] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02624|Homoserine Lactone SLC9A1 common genes common pathways GO:0055085| transmembrane transport SLC9A1;ABCB1 GO:1902533| TNFSF11;SLC9A1 GO:0071456| cellular response to hypoxia PTGS2;SLC9A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;SLC9A1 GO:0014070| response to organic cyclic compound PTGS2;SLC9A1 GO:0030154| cell differentiation SLC9A1;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;SLC9A1 GO:0043065| positive regulation of apoptotic process PTGS2;SLC9A1 38063:[DB00480 DB08595] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08595|4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 38064:[DB00480 DB11348] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0098869| PTGS2;ALB GO:0051260| protein homooligomerization SLC34A1;TNFSF11 GO:0034605| cellular response to heat PTGS2;PDCD6 GO:0032355| response to estradiol stimulus PTGS2;SLC34A1;CALR GO:0007568| aging PTGS2;CANX;RGN GO:0006810| transport SLC20A2;SRI;CACNB4;SLC20A1;CACNB1;CACNB3;CACNA1I;CACNA1E;ABCB1 GO:0071456| cellular response to hypoxia CASR;SLC8A1;PTGS2;S100B GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;NRXN1 GO:0010033| response to organic substance CASQ1;CALR;PTGS2 GO:0055085| transmembrane transport CACNA1A;CACNA1I;CACNA1G;CACNA1E;TRPV6;ABCB1;CACNA1F;CATSPER1;SLC34A3;RYR1;SLC34A2;TRPV5;RYR3;SLC8A1;CACNA1D;CACNA1C;SLC20A2;RYR2;CACNA1S;CALM1;CACNA1H;SLC20A1 GO:0043066| negative regulation of apoptotic process ALB;TPT1;PTGS2;CIB1;RGN GO:0008284| positive regulation of cell proliferation CASR;CALR;S100A13;PTGS2;CIB1;S100B GO:0007155| cell adhesion CDH5;CIB1;NRXN1 GO:0034097| response to cytokine stimulus PTGS2;SPARC GO:0071318| cellular response to ATP CIB2;RYR3;PTGS2 GO:0042127| regulation of cell proliferation CIB1;SPARC;PTGS2 GO:0007612| learning PTGS2;NRXN1 GO:0032496| response to lipopolysaccharide PTGS2;SPARC GO:0042493| response to drug ABCB1;CALR;PTGS2;SLC34A1;SLC8A1 GO:0045907| positive regulation of vasoconstriction PTGS2;CASR GO:0019722| calcium-mediated signaling RYR2;TNFSF11 GO:0051384| response to glucocorticoid stimulus S100B;SPARC;PTGS2 GO:0030154| cell differentiation TPT1;TNFSF11;CIB1;CALR3;CATSPER1 GO:0007613| memory PTGS2;S100B GO:0008285| negative regulation of cell proliferation CIB1;CDH5;PTGS2 GO:0014070| response to organic cyclic compound CASR;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;S100B GO:0001503| ossification SLC34A1;SPARC;CASR;TNFSF11 GO:0007275| multicellular organismal development RYR2;TNFSF11;CATSPER1;RYR1 GO:0001525| angiogenesis PTGS2;PDCD6;CIB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100A13;SLC20A1;S100B;TNFSF11 GO:0055074| calcium ion homeostasis TNFSF11;CALB1;TRPV6;SLC8A1;CIB2;TRPV5 GO:0051092| positive regulation of NF-kappaB transcription factor activity CIB1;TNFSF11 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;CIB1 38065:[DB00480 DB08230] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08230|5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;PTGS2 GO:0007275| multicellular organismal development PIM1;TNFSF11 38066:[DB00480 DB07644] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07644|5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine DCPS common genes common pathways 38067:[DB00480 DB09389] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0014070| response to organic cyclic compound SRD5A1;PTGS2 GO:0030154| cell differentiation SRD5A1;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;SRD5A1;CYP3A4 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006810| transport ABCB1;AR GO:0032355| response to estradiol stimulus SRD5A1;PTGS2 GO:0055114| oxidation-reduction process SRD5A1;PTGS2;CYP19A1;CYP3A4 GO:0042493| response to drug ABCB1;SRD5A1;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PGR;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 38068:[DB00480 DB12191] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12191|Obatoclax BCL2 common genes common pathways GO:0009314| response to radiation BCL2;PTGS2 GO:0001503| ossification BCL2;TNFSF11 GO:0008285| negative regulation of cell proliferation BCL2;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;PTGS2 GO:0042493| response to drug BCL2;ABCB1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;BCL2 GO:0043066| negative regulation of apoptotic process BCL2;PTGS2 GO:0034097| response to cytokine stimulus BCL2;PTGS2 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0009887| organ morphogenesis TNFSF11;BCL2 GO:0098609| BCL2;CDH5 GO:0071456| cellular response to hypoxia BCL2;PTGS2 GO:0006979| response to oxidative stress PTGS2;BCL2 38069:[DB00480 DB04352] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04352|beta-D-Ribose-5-phosphate NUDT9 common genes common pathways 38070:[DB00480 DB03626] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03626|5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NQO1 GO:0043066| negative regulation of apoptotic process PTGS2;NQO1 GO:0006979| response to oxidative stress NQO1;PTGS2 GO:0007568| aging PTGS2;NQO1 GO:0032355| response to estradiol stimulus PTGS2;NQO1 GO:0014070| response to organic cyclic compound PTGS2;NQO1 38071:[DB00480 DB03727] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03727|Coproporphyrin I UROD common genes common pathways 38072:[DB00480 DB00409] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00409|Remoxipride DRD2;DRD4;DRD3;HTR2A;SIGMAR1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory PTGS2;HTR2A GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;HTR2A;PTGS2 GO:0007612| learning PTGS2;DRD3 GO:0042493| response to drug DRD2;HTR2A;PTGS2;DRD3;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 38073:[DB00480 DB08807] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0042493| response to drug PTGS2;ABCB1;HTR1B GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0007568| aging ADRB3;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;ADRB3;ADRB1;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 38074:[DB00480 DB08406] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08406|[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 38075:[DB00480 DB00578] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00578|Carbenicillin PLA2G4A;SLC22A6 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLA2G4A GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0006629| lipid metabolic process PTGS2;PLA2G4A 38076:[DB00480 DB07708] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07708|3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 38077:[DB00480 DB03006] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03006|Arsanilic acid LYZ common genes common pathways GO:0006954| inflammatory response LYZ;PTGS2 38078:[DB00480 DB05483] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05483|PCL-016 UBR4;ZFY common genes common pathways GO:0007275| multicellular organismal development ZFY;TNFSF11 GO:0016567| protein ubiquitination CRBN;UBR4 38079:[DB00480 DB08461] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08461|3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL AR common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0006810| transport AR;ABCB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 38080:[DB00480 DB08751] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08751|N,N'-DIMETHYL-N-(ACETYL)-N'-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)ETHYLENEDIAMINE HRAS common genes common pathways GO:0046330| positive regulation of JNK cascade HRAS;TNFSF11 GO:0008284| positive regulation of cell proliferation HRAS;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HRAS;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HRAS GO:0009887| organ morphogenesis HRAS;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;HRAS 38081:[DB00480 DB01153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01153|Sertaconazole CYP51A1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP51A1 GO:0006629| lipid metabolic process PTGS2;CYP51A1 38082:[DB00480 DB07172] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07172|(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid PPARG common genes common pathways GO:0010033| response to organic substance PTGS2;PPARG GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 38083:[DB00480 DB00589] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2B;HTR2A;TNFSF11;ADRA2A GO:0007568| aging PTGS2;HTR2A GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP3A4 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug DRD2;DRD1;HTR2A;HTR2B;PTGS2;HTR2C;ABCB1;HTR1B;DRD3 GO:0007612| learning DRD5;DRD3;PTGS2;DRD1 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2B;PTGS2;HTR1A;HTR2A;DRD3;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0007613| memory PTGS2;DRD1;HTR2A GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;ADRA2C GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 38084:[DB00480 DB01070] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01070|Dihydrotachysterol VDR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 GO:0046697| decidualization PTGS2;VDR GO:0009887| organ morphogenesis VDR;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;VDR GO:0008285| negative regulation of cell proliferation CDH5;VDR;PTGS2 38085:[DB00480 DB04683] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04683|(2R)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(9E)-HEXADEC-9-ENOYLOXY]PROPYL (9E)-OCTADEC-9-ENOATE NR5A1 common genes common pathways GO:0030154| cell differentiation TNFSF11;NR5A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR5A1;TNFSF11 38086:[DB00480 DB05505] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05505|NM-702 TBXAS1 common genes common pathways GO:0055114| oxidation-reduction process TBXAS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;TBXAS1 GO:0019371| cyclooxygenase pathway TBXAS1;PTGS2 GO:0006629| lipid metabolic process TBXAS1;PTGS2 GO:0006693| prostaglandin metabolic process TBXAS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;TBXAS1 GO:0006633| fatty acid biosynthetic process TBXAS1;PTGS2 38087:[DB00480 DB02763] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02763|5-Mercapto-2-Nitro-Benzoic Acid arsC;IL12B common genes common pathways GO:0010033| response to organic substance IL12B;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;IL12B GO:0019233| sensory perception of pain IL12B;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;IL12B 38088:[DB00480 DB08847] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08847|Hydroxyproline SLC36A1 common genes common pathways GO:0055085| transmembrane transport SLC36A1;ABCB1 38089:[DB00480 DB02383] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02383|Tolrestat AKR1B1;AKR1A1;AKR1B10 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B10;AKR1A1;AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0010033| response to organic substance PTGS2;AKR1B1 38090:[DB00480 DB11607] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11607|Efmoroctocog alfa VWF common genes common pathways GO:0007155| cell adhesion CDH5;VWF GO:0051260| protein homooligomerization VWF;TNFSF11 38091:[DB00480 DB05039] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0006810| transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;UGT1A1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 38092:[DB00480 DB04825] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCB1;CALM1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38093:[DB00480 DB00152] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00152|Thiamine TPK1;SLC19A2;CYP4B1;SLC22A2;SLC22A1;SLC22A5 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0055085| transmembrane transport SLC22A2;SLC22A5;ABCB1;SLC22A1 GO:0055114| oxidation-reduction process CYP4B1;PTGS2 GO:0006855| drug transmembrane transport SLC22A2;SLC22A5;ABCB1;SLC22A1 38094:[DB00480 DB04964] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04964|Oregovomab MUC16 common genes common pathways GO:0007155| cell adhesion CDH5;MUC16 38095:[DB00480 DB07225] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07225|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE CTSB common genes common pathways GO:0046697| decidualization CTSB;PTGS2 38096:[DB00480 DB05476] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05476|WX-UK1 PLAUR common genes common pathways GO:0043066| negative regulation of apoptotic process PLAUR;PTGS2 38097:[DB00480 DB04727] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04727|N-(4-{4-AMINO-6-[4-(METHYLOXY)PHENYL]FURO[2,3-D]PYRIMIDIN-5-YL}PHENYL)-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA KDR common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;PTGS2 GO:0043066| negative regulation of apoptotic process KDR;PTGS2 GO:0030154| cell differentiation KDR;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0001525| angiogenesis PTGS2;KDR GO:0007275| multicellular organismal development TNFSF11;KDR 38098:[DB00480 DB00097] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00097|Choriogonadotropin alfa LHCGR;FSHR common genes common pathways GO:0045670| regulation of osteoclast differentiation LHCGR;TNFSF11;FSHR 38099:[DB00480 DB03971] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03971|Acarbose Derived Hexasaccharide AMY2A;AMY2A common genes common pathways 38100:[DB00480 DB00210] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes PTGS2 common pathways GO:0055114| oxidation-reduction process PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0009750| response to fructose stimulus PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0034097| response to cytokine stimulus RARA;PTGS2 GO:0043066| negative regulation of apoptotic process RARG;PTGS2;RARA;RARB GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARA;RARG;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RXRB;RARB;RXRA;RARG;RXRG;RARA GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:1990830| TNFSF11;RARG GO:0007568| aging PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0032355| response to estradiol stimulus PTGS2;RARA GO:1902219| PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process RARB;PTGS2;RARG GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;RARB;RARG;PTGS2;RARA GO:0008217| regulation of blood pressure PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0007566| embryo implantation PTGS2;RXRA GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 38101:[DB00480 DB07848] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07848|5-Chloro-N-{(3S)-1-[(2S)-1-(4-morpholinyl)-1-oxo-2-propanyl]-2-oxo-3-pyrrolidinyl}-1H-indole-2-sulfonamide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 38102:[DB00480 DB05421] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05421|CP-122721 TACR1 common genes common pathways GO:0032355| response to estradiol stimulus TACR1;PTGS2 GO:0019233| sensory perception of pain PTGS2;TACR1 GO:0006954| inflammatory response TACR1;PTGS2 GO:0045907| positive regulation of vasoconstriction TACR1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0008217| regulation of blood pressure TACR1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;TACR1 38103:[DB00480 DB01155] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 38104:[DB00480 DB01800] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01800|N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium ARSA common genes common pathways 38105:[DB00480 DB06921] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06921|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 38106:[DB00480 DB05431] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05431|MLN-977 ALOX5 common genes common pathways GO:0006954| inflammatory response ALOX5;PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0055114| oxidation-reduction process PTGS2;ALOX5 38107:[DB00480 DB02998] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0006810| transport ABCB1;AR GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;NCOA2;TNFSF11 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 38108:[DB00480 DB14635] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes ABCB1 common pathways GO:0010033| response to organic substance PTGS2;PPARG;CYP1A2 GO:0009887| organ morphogenesis VDR;TNFSF11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCC5;ABCB1 GO:0098869| PTGS2;GSTA1;GSTP1 GO:0046697| decidualization PTGS2;VDR GO:0006810| transport ABCB1;ABCC5 GO:0032355| response to estradiol stimulus PTGS2;GSTP1;CYP1A2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP1A2;CYP2C9;CYP2B6;CYP2D6;CYP3A4;PTGS2;CBR1 GO:0042493| response to drug PTGS2;CYP1A2;PPARG;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11;PPARG GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:1901529| ABCB1 GO:0008285| negative regulation of cell proliferation VDR;PTGS2;PPARG;CDH5 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound PPARG;CYP1A2;PTGS2 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0019371| cyclooxygenase pathway CBR1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP2C9;CYP1A2;PPARG;CYP3A4 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0007275| multicellular organismal development VDR;TNFSF11 38109:[DB00480 DB11712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055085| transmembrane transport CFTR;ABCB1 GO:0098869| ALB;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP3A5;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 38110:[DB00480 DB02813] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter HEXB;TNFSF11 38111:[DB00480 DB04318] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04318|Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide MMP11 common genes common pathways GO:0007275| multicellular organismal development MMP11;TNFSF11 38112:[DB00480 DB02177] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02177|1-Acetyl-4-(4-{4-[(2-Ethoxyphenyl)Thio]-3-Nitrophenyl}Pyridin-2-Yl)Piperazine ITGAL common genes common pathways GO:0098609| CDH5;ITGAL GO:0007155| cell adhesion CDH5;ITGAL GO:0006954| inflammatory response PTGS2;ITGAL 38113:[DB00480 DB02142] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02142|Pyridoxamine-5'-Phosphate hisC;dat;CCBL1;hisC;BCAT2 common genes common pathways GO:1990830| BCAT2;TNFSF11 38114:[DB00480 DB06912] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06912|UNDECA-3,7-DIENE-1,3,7,11-TETRACARBALDEHYDE LYZ common genes common pathways GO:0006954| inflammatory response PTGS2;LYZ 38115:[DB00480 DB12334] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12334|Milataxel TUBB1;TUBB common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB;ABCB1 38116:[DB00480 DB06157] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06157|Istaroxime ATP2A2;ATP1A1 common genes common pathways GO:0007155| cell adhesion ATP2A2;CDH5 GO:0042493| response to drug PTGS2;ATP1A1;ABCB1 GO:0008217| regulation of blood pressure PTGS2;ATP1A1 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 38117:[DB00480 DB08082] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08082|N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0042493| response to drug MAOB;PTGS2;ABCB1 GO:0055114| oxidation-reduction process MAOB;PTGS2 38118:[DB00480 DB07462] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0042493| response to drug PTGS2;COMT;ABCB1 GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0007612| learning PTGS2;COMT GO:0014070| response to organic cyclic compound COMT;PTGS2 38119:[DB00480 DB09303] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09303|Evolocumab PCSK9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PCSK9 GO:0010469| regulation of receptor activity PCSK9;TNFSF11 38120:[DB00480 DB01284] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01284|Tetracosactide MC2R common genes common pathways 38121:[DB00480 DB03484] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03484|L-Alpha-Glycerophosphorylethanolamine ANXA5 common genes common pathways GO:0010033| response to organic substance ANXA5;PTGS2 GO:0043066| negative regulation of apoptotic process ANXA5;PTGS2 38122:[DB00480 DB05913] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05913|OSI-930 KIT;FLT1 common genes common pathways GO:0002548| monocyte chemotaxis TNFSF11;FLT1 GO:0019221| cytokine-mediated signaling pathway TNFSF11;KIT GO:0051897| positive regulation of protein kinase B signaling cascade KIT;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;KIT GO:0008284| positive regulation of cell proliferation FLT1;PTGS2;KIT GO:0043406| positive regulation of MAP kinase activity TNFSF11;FLT1;KIT GO:0006954| inflammatory response PTGS2;KIT GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;KIT GO:0001525| angiogenesis FLT1;PTGS2 GO:0007275| multicellular organismal development FLT1;TNFSF11 GO:0009314| response to radiation KIT;PTGS2 GO:0030154| cell differentiation FLT1;TNFSF11 38123:[DB00480 DB04010] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04010|2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide PARP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 38124:[DB00480 DB06124] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06124|L-aminocarnityl-succinyl-leucyl-argininal-diethylacetal CAPN3 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CAPN3 GO:0043066| negative regulation of apoptotic process CAPN3;PTGS2 38125:[DB00480 DB12200] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12200|Tivantinib MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 38126:[DB00480 DB06366] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06366|Pertuzumab ERBB2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;ERBB2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ERBB2 38127:[DB00480 DB04590] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04590|(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F7 GO:0032355| response to estradiol stimulus F7;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;F7 38128:[DB00480 DB05668] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05668|Palifosfamide DNMT1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;DNMT1 38129:[DB00480 DB04758] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04758|2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;F7 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0051897| positive regulation of protein kinase B signaling cascade F7;TNFSF11 38130:[DB00480 DB05404] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05404|AZD 3355 TP53 common genes common pathways GO:0007568| aging TP53;PTGS2 GO:0071456| cellular response to hypoxia TP53;PTGS2 GO:0034605| cellular response to heat PTGS2;TP53 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;TP53 GO:0006979| response to oxidative stress TP53;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;TP53 GO:0043066| negative regulation of apoptotic process PTGS2;TP53 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TP53;TNFSF11 GO:0042493| response to drug TP53;PTGS2;ABCB1 GO:0010243| response to organic nitrogen TP53;PTGS2 GO:0030154| cell differentiation TNFSF11;TP53 GO:0034644| cellular response to UV PTGS2;TP53 GO:0014070| response to organic cyclic compound TP53;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;TP53;PTGS2 GO:0007275| multicellular organismal development TNFSF11;TP53 GO:0043065| positive regulation of apoptotic process TP53;PTGS2 38131:[DB00480 DB06101] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06101|IMC-1C11 FLT1;KDR;FLT4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;FLT1 GO:0043066| negative regulation of apoptotic process PTGS2;FLT4;KDR GO:0008284| positive regulation of cell proliferation FLT1;KDR;FLT4;PTGS2 GO:0046330| positive regulation of JNK cascade FLT4;TNFSF11 GO:0002548| monocyte chemotaxis FLT1;TNFSF11 GO:0030154| cell differentiation KDR;FLT1;TNFSF11 GO:0007275| multicellular organismal development KDR;FLT1;TNFSF11 GO:0001525| angiogenesis PTGS2;FLT4;KDR;FLT1 GO:0010575| positive regulation vascular endothelial growth factor production FLT4;PTGS2 GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 38132:[DB00480 DB03691] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03691|WRR-112 CTSF common genes common pathways 38133:[DB00480 DB04461] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04461|Coproporphyrinogen III UROD common genes common pathways 38134:[DB00480 DB07039] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07039|(2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide AR common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0006810| transport AR;ABCB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 38135:[DB00480 DB11059] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11059|Carboxymethylcellulose SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLC2A1;ABCB1 GO:0071260| cellular response to mechanical stimulus PTGS2;SLC2A1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 38136:[DB00480 DB04325] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04325|Phenethylamine PRSS2;PRSS1 common genes common pathways 38137:[DB00480 DB06973] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06973|4,4'-PROPANE-2,2-DIYLDIPHENOL ESRRG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;TNFSF11 38138:[DB00480 DB03403] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 38139:[DB00480 DB00685] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 38140:[DB00480 DB02712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02712|Sorbinil AKR1B1 common genes common pathways GO:0010033| response to organic substance PTGS2;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 38141:[DB00480 DB06237] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0043406| positive regulation of MAP kinase activity PDE5A;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38142:[DB00480 DB08497] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08497|(1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate CASP3 common genes common pathways GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0010033| response to organic substance PTGS2;CASP3 GO:0032496| response to lipopolysaccharide PTGS2;CASP3 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process PTGS2;CASP3 GO:0042493| response to drug ABCB1;PTGS2;CASP3 GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0014070| response to organic cyclic compound CASP3;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CASP3 38143:[DB00480 DB08155] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08155|N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE CA1;CA2 common genes common pathways GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0010033| response to organic substance PTGS2;CA2 GO:0045780| positive regulation of bone resorption CA2;TNFSF11 38144:[DB00480 DB04109] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04109|[4-(1,3,2-Dioxaborolan-2-Yloxy)Methyl]Benzamidine PRSS3 common genes common pathways 38145:[DB00480 DB07428] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07428|4-[(5-methoxy-2-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB GO:0008217| regulation of blood pressure HBB;PTGS2 GO:0098869| HBB;HBA1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB 38146:[DB00480 DB04074] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:1990830| TNFSF11;BCAT2 GO:0055085| transmembrane transport SLC16A7;SLC16A1;ABCB1;SLC16A3 GO:0006629| lipid metabolic process PTGS2;SLC16A1 38147:[DB00480 DB02180] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02180|Myristoyl-Coa NMT1;NMT2 common genes common pathways 38148:[DB00480 DB03239] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03239|3',5'-Dinitro-N-Acetyl-L-Thyronine TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport TTR;ABCB1 38149:[DB00480 DB01102] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007568| aging ADRB3;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1;ADRB3 38150:[DB00480 DB04843] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 38151:[DB00480 DB07067] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07067|(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion DPP4;CDH5 38152:[DB00480 DB05191] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05191|Atl146e ADORA2A common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;ADORA2A GO:0006954| inflammatory response ADORA2A;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;ADORA2A;CDH5 GO:0042493| response to drug ABCB1;ADORA2A;PTGS2 GO:0050728| negative regulation of inflammatory response ADORA2A;CDH5 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 38153:[DB00480 DB01834] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01834|(9R,10R)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTP1;GSTM1 common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2 GO:0098869| PTGS2;GSTP1 GO:0032355| response to estradiol stimulus PTGS2;GSTP1 38154:[DB00480 DB12458] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12458|Muscimol GABRA1;GABRB3;GABRG2 common genes common pathways GO:0006810| transport GABRB3;GABRA1;ABCB1;GABRG2 38155:[DB00480 DB11703] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;BTK GO:0055114| oxidation-reduction process CYP3A7;CYP3A5;PTGS2;CYP3A43;CYP3A4 GO:0010033| response to organic substance PTGS2;BTK GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;BTK GO:0019722| calcium-mediated signaling TNFSF11;BTK 38156:[DB00480 DB03268] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03268|RU82197 SRC common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| CDH5;SRC GO:1902533| TNFSF11;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 38157:[DB00480 DB03225] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03225|D-Tryptophan DAO;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 GO:0055114| oxidation-reduction process PTGS2;DAO 38158:[DB00480 DB00902] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00902|Methdilazine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 38159:[DB00480 DB03593] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03593|N7-Methyl-Guanosine-5'-Monophosphate DCPS common genes common pathways 38160:[DB00480 DB05087] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0006810| transport GABRA4;GABRA6;GABRA5;GABRA3;ABCB1;GABRA1 38161:[DB00480 DB04840] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging PTGS2;CYP1A1 GO:0042493| response to drug ABCB1;PTGS2;SLC6A2;CYP1A1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2;CYP1A1 GO:2001225| regulation of chloride transport ABCB1 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:1901529| ABCB1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0006855| drug transmembrane transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP2D6 38162:[DB00480 DB04562] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04562|Tricarballylic Acid ACO2 common genes common pathways 38163:[DB00480 DB09304] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09304|Setiptiline ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7 common genes common pathways GO:0042493| response to drug HTR2B;PTGS2;HTR2A;ABCB1;HTR1B;HTR2C GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA2A;HTR2B;PTGS2;HTR1A;HTR2A GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;ADRA2A;TNFSF11 GO:0007568| aging PTGS2;HTR2A GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0007613| memory PTGS2;HTR2A GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;ADRA2C 38164:[DB00480 DB00886] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00886|Omapatrilat ACE;MME common genes common pathways GO:0019233| sensory perception of pain MME;PTGS2 GO:0008217| regulation of blood pressure ACE;PTGS2 38165:[DB00480 DB01626] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01626|Pargyline MAOB;MAOA common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0042493| response to drug PTGS2;MAOB;ABCB1 GO:0055114| oxidation-reduction process PTGS2;MAOA;MAOB 38166:[DB00480 DB05351] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways GO:0006810| transport ABCB1;ATP4A GO:0032496| response to lipopolysaccharide ATP4B;PTGS2 GO:0007155| cell adhesion ATP4B;CDH5 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;PTGS2 GO:0010243| response to organic nitrogen ATP4B;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38167:[DB00480 DB14642] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0010033| response to organic substance AVPR1A;PTGS2 GO:0006810| transport ABCC2;ABCB1 GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0042493| response to drug PTGS2;ABCB1;ABCC2 GO:0032496| response to lipopolysaccharide ABCC2;PTGS2 GO:0034097| response to cytokine stimulus AVPR2;PTGS2 GO:0008284| positive regulation of cell proliferation AVPR1A;AVPR2;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process AVPR1A;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0019722| calcium-mediated signaling AVPR1A;TNFSF11 GO:0045907| positive regulation of vasoconstriction AVPR1A;AVPR2;PTGS2;AVPR1B 38168:[DB00480 DB04865] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04865|Omacetaxine mepesuccinate RPL3 common genes common pathways 38169:[DB00480 DB06536] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0006629| lipid metabolic process PPARG;PPARA;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0050728| negative regulation of inflammatory response PPARA;CDH5 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0042493| response to drug ABCB1;PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PPARA;TNFSF11 38170:[DB00480 DB01081] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01081|Diphenoxylate OPRM1;OPRD1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0006955| immune response TNFSF11;OPRD1 GO:0009314| response to radiation PTGS2;OPRM1 GO:0019233| sensory perception of pain OPRM1;PTGS2;OPRD1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 38171:[DB00480 DB01219] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007275| multicellular organismal development TNFSF11;RYR1 GO:0055085| transmembrane transport ABCB1;RYR1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38172:[DB00480 DB09166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0006810| transport GABRA3;GABRA1;GABRG2;ABCB1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PTAFR GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C18;CYP2C19 GO:0032496| response to lipopolysaccharide PTAFR;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTAFR;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;PTAFR GO:0006954| inflammatory response PTAFR;PTGS2 GO:0006955| immune response PTAFR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38173:[DB00480 DB08760] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08760|(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid PPARG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0010033| response to organic substance PTGS2;PPARG 38174:[DB00480 DB12945] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12945|Dihydralazine CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 38175:[DB00480 DB04889] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0007613| memory SLC6A4;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0042493| response to drug SLC6A2;PTGS2;MAOB;DRD2;ABCB1;SLC6A4 GO:0055114| oxidation-reduction process MAOB;PTGS2;CYP2D6 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0006810| transport ABCB1;SLC6A2 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2 38176:[DB00480 DB07642] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07642|5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine DCPS common genes common pathways 38177:[DB00480 DB04872] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04872|Osanetant TACR3 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;TACR3 GO:0007568| aging TACR3;PTGS2 38178:[DB00480 DB04187] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04187|(9S,10S)-9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene GSTM1 common genes common pathways 38179:[DB00480 DB01569] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01569|Formebolone HSD11B2 common genes common pathways GO:0042493| response to drug PTGS2;HSD11B2;ABCB1 GO:0055114| oxidation-reduction process HSD11B2;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;HSD11B2 38180:[DB00480 DB03414] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03414|5-Thio-a/B-D-Mannopyranosylamine MAN2A1 common genes common pathways 38181:[DB00480 DB05434] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0008285| negative regulation of cell proliferation CXCL8;CDH5;PTGS2 GO:0072089| stem cell proliferation FGF2;ABCB1 GO:0019722| calcium-mediated signaling CXCL8;TNFSF11 GO:0030154| cell differentiation VEGFA;FGF2;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;HGF;PTGS2 GO:0006954| inflammatory response CXCL8;PTGS2 GO:0006955| immune response CXCL8;TNFSF11 GO:0001525| angiogenesis CXCL8;FGF2;PTGS2;VEGFA GO:0007275| multicellular organismal development VEGFA;TNFSF11;FGF2 GO:0042327| positive regulation of phosphorylation TNFSF11;VEGFA GO:0009887| organ morphogenesis TNFSF11;FGF2 GO:0043406| positive regulation of MAP kinase activity FGF2;TNFSF11;VEGFA GO:0010469| regulation of receptor activity VEGFA;HGF;CXCL8;TNFSF11;FGF2 GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0050728| negative regulation of inflammatory response CDH5;HGF GO:0051897| positive regulation of protein kinase B signaling cascade HGF;FGF2;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;TNFSF11;HGF;VEGFA GO:0008284| positive regulation of cell proliferation FGF2;VEGFA;HGF;PTGS2 GO:0043066| negative regulation of apoptotic process VEGFA;PTGS2;HGF GO:0060749| mammary gland alveolus development TNFSF11;VEGFA 38182:[DB00480 DB06731] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06731|Seproxetine CYP3A5;CYP3A7;CYP2C9;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP3A7;CYP3A5;CYP2C9 38183:[DB00480 DB04760] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04760|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(4-FLUORO-3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways GO:0030282| bone mineralization MMP13;PTGS2 38184:[DB00480 DB05792] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05792|Arylacenamide SIGMAR1 common genes common pathways 38185:[DB00480 DB00517] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 38186:[DB00480 DB08838] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0055074| calcium ion homeostasis GRIN1;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;GRIN1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0019233| sensory perception of pain PTGS2;GRIN1 GO:0008217| regulation of blood pressure CACNA1B;PTGS2;NISCH GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A3;SLC22A2 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA2C GO:0019722| calcium-mediated signaling TNFSF11;GRIN1 GO:0007613| memory GRIN1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 GO:0007612| learning GRIN1;PTGS2 GO:0055085| transmembrane transport CACNA1B;SLC22A2;ABCB1;SLC22A1;SLC22A3 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0006810| transport SLC7A7;CHRNA1;CACNA1B;ASIC3;ABCB1 38187:[DB00480 DB00131] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PDE4D GO:0071456| cellular response to hypoxia PTGS2;PRKAA1 GO:0007568| aging CREB1;PTGS2;PDE4D GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;CREB1 GO:1990830| TNFSF11;CREB1 GO:0010033| response to organic substance PTGS2;CREB1;ACSL1;AMPD1 GO:0008284| positive regulation of cell proliferation PTGS2;PRKAA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;CREB1 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2;PRKAA1 GO:0042493| response to drug ADCY1;ABCB1;ACSL1;PTGS2;CREB1 GO:0006631| fatty acid metabolic process PTGS2;PRKAA1;PRKAB2;ACSL1;PRKAB1 GO:0010226| response to lithium ion PTGS2;ADCY1 GO:0007613| memory CREB1;PTGS2 GO:0030154| cell differentiation CREB1;TNFSF11 GO:0006633| fatty acid biosynthetic process PTGS2;PRKAB2;PRKAA1;PRKAB1 GO:0014070| response to organic cyclic compound ACSL1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;PIM1 GO:0045672| positive regulation of osteoclast differentiation CREB1;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;CREB1 GO:0006629| lipid metabolic process PTGS2;PRKAB2;PRKAA1;PRKAB1;ACSL1 38188:[DB00480 DB06288] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0042493| response to drug DRD3;ABCB1;PTGS2;HTR2A;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11 GO:0008284| positive regulation of cell proliferation DRD3;HTR2A;PTGS2 GO:0007612| learning PTGS2;DRD3 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging HTR2A;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory PTGS2;HTR2A 38189:[DB00480 DB03059] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03059|Acetoacetyl-CoA HADH;ACADS;ECHS1 common genes common pathways GO:0006629| lipid metabolic process ECHS1;PTGS2;HADH;ACADS GO:0055114| oxidation-reduction process PTGS2;HADH;ACADS GO:0006631| fatty acid metabolic process HADH;ACADS;ECHS1;PTGS2 GO:0042493| response to drug ABCB1;HADH;PTGS2 38190:[DB00480 DB04066] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04066|para-Coumaric Acid PTGR1;hutH common genes common pathways GO:0055114| oxidation-reduction process PTGR1;PTGS2 GO:0006693| prostaglandin metabolic process PTGR1;PTGS2 38191:[DB00480 DB09282] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0043406| positive regulation of MAP kinase activity PDE5A;TNFSF11 38192:[DB00480 DB06098] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06098|PRLX 93936 VDAC2;VDAC3 common genes common pathways GO:0055085| transmembrane transport ABCB1;VDAC2;VDAC3 GO:0007612| learning PTGS2;VDAC3 38193:[DB00480 DB08326] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08326|2-(6-HYDROXY-1,3-BENZOTHIAZOL-2-YL)-1,3-THIAZOL-4(5H)-ONE ACSBG1 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;ACSBG1 GO:0006629| lipid metabolic process PTGS2;ACSBG1 GO:0006631| fatty acid metabolic process ACSBG1;PTGS2 38194:[DB00480 DB08846] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08846|Ellagic Acid CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA9;CA12;CA14;CSNK2A1;PRKACA;PRKCA;PRKCB;SYK;SQLE;CYP1A1;CYP2E1;SLC22A6;SLC22A11 common genes common pathways GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PRKCB;TNFSF11 GO:0001525| angiogenesis PRKCA;SYK;PTGS2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0006954| inflammatory response PTGS2;SYK GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCB;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0007257| activation of JUN kinase activity TNFSF11;SYK GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0007155| cell adhesion PRKCA;CDH5 GO:0008284| positive regulation of cell proliferation CSNK2A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;CYP1A1;PTGS2;SQLE GO:2001225| regulation of chloride transport ABCB1;CA2;CA7 GO:0042493| response to drug ABCB1;CYP1A1;CA9;CYP2E1;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006979| response to oxidative stress PTGS2;CA3 GO:0007568| aging PTGS2;CYP1A1 GO:0045780| positive regulation of bone resorption SYK;CA2;PRKCA;TNFSF11 GO:0034605| cellular response to heat PTGS2;PRKACA GO:0010033| response to organic substance CYP1A1;CA2;PTGS2;SQLE GO:0009887| organ morphogenesis TNFSF11;SYK GO:0055085| transmembrane transport SLC22A6;SLC22A11;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA 38195:[DB00480 DB03349] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03349|8-Bromo-Adenosine-5'-Monophosphate PDE4B;HINT1 common genes common pathways 38196:[DB00480 DB02872] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02872|Cis-[4,5-Bis-(4-Bromophenyl)-2-(2-Ethoxy-4-Methoxyphenyl)-4,5-Dihydroimidazol-1-Yl]-[4-(2-Hydroxyethyl)Piperazin-1-Yl]Methanone MDM2 common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;MDM2 GO:0042493| response to drug PTGS2;ABCB1;MDM2 GO:0016567| protein ubiquitination CRBN;MDM2 GO:0043066| negative regulation of apoptotic process MDM2;PTGS2 GO:0008284| positive regulation of cell proliferation MDM2;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;MDM2 38197:[DB00480 DB08822] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08822|Azilsartan medoxomil AGTR1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;AGTR1 GO:0019722| calcium-mediated signaling TNFSF11;AGTR1 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 38198:[DB00480 DB02837] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02837|O4-Sulfonylgalactose MBL2 common genes common pathways GO:0006979| response to oxidative stress MBL2;PTGS2 38199:[DB00480 DB11094] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;VDR;CYP27B1;PTGS2 GO:0033280| response to vitamin D PTGS2;CYP27B1 GO:0055074| calcium ion homeostasis CYP27B1;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007275| multicellular organismal development TNFSF11;VDR GO:0009887| organ morphogenesis TNFSF11;VDR GO:0030282| bone mineralization PTGS2;CYP27B1 GO:0046697| decidualization PTGS2;CYP27B1;VDR GO:0055114| oxidation-reduction process CYP3A4;CYP2R1;CYP27B1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VDR GO:0032496| response to lipopolysaccharide CYP27B1;PTGS2 38200:[DB00480 DB05418] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05418|GW 597599 TACR1 common genes common pathways GO:0032355| response to estradiol stimulus TACR1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;TACR1 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;TACR1 GO:0014070| response to organic cyclic compound PTGS2;TACR1 GO:0019233| sensory perception of pain PTGS2;TACR1 GO:0006954| inflammatory response PTGS2;TACR1 38201:[DB00480 DB01080] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0007568| aging ABAT;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC36A1 GO:0042493| response to drug ABAT;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PTGS2 38202:[DB00480 DB05218] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05218|PN0621 TNF common genes common pathways GO:0007275| multicellular organismal development TNFSF11;TNF GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0006955| immune response TNF;TNFSF11 GO:0006954| inflammatory response TNF;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;TNFSF11 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2 GO:0010033| response to organic substance PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0009887| organ morphogenesis TNF;TNFSF11 38203:[DB00480 DB07976] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07976|3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0042493| response to drug DHODH;PTGS2;ABCB1 GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;DHODH 38204:[DB00480 DB03791] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03791|(3-{3-[[2-Chloro-3-(Trifluoromethyl)Benzyl](2,2-Diphenylethyl)Amino]Propoxy}Phenyl)Acetic Acid NR1H2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H2;TNFSF11 38205:[DB00480 DB02499] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02499|Dinor-N(Omega)-Hydroxy-L-Arginine ARG1 common genes common pathways GO:0007568| aging PTGS2;ARG1 GO:0042493| response to drug ARG1;PTGS2;ABCB1 GO:0010042| response to manganese ion PTGS2;ARG1 GO:0032496| response to lipopolysaccharide ARG1;PTGS2 38206:[DB00480 DB02109] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02109|Hadacidin purA;ADSSL1 common genes common pathways 38207:[DB00480 DB03415] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03415|3-Thiaoctanoyl-Coenzyme A ACADM common genes common pathways GO:0006629| lipid metabolic process ACADM;PTGS2 GO:0006631| fatty acid metabolic process ACADM;PTGS2 GO:0055114| oxidation-reduction process PTGS2;ACADM 38208:[DB00480 DB05408] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05408|Emricasan CASP1;CASP3;CASP7 common genes common pathways GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0010033| response to organic substance CASP3;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CASP3 GO:0042493| response to drug PTGS2;CASP3;ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;CASP3;CASP1 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;CASP3 GO:0014070| response to organic cyclic compound PTGS2;CASP3 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CASP1 GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0050727| regulation of inflammatory response CASP1;PTGS2 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2 38209:[DB00480 DB06999] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06999|N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide BRAF common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;BRAF GO:0043066| negative regulation of apoptotic process PTGS2;BRAF GO:0009887| organ morphogenesis BRAF;TNFSF11 GO:0030154| cell differentiation BRAF;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BRAF 38210:[DB00480 DB07435] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07435|1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE POLK;polA common genes common pathways GO:0034644| cellular response to UV POLK;PTGS2 38211:[DB00480 DB00405] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00405|Dexbrompheniramine HRH1 common genes common pathways GO:0006954| inflammatory response PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 38212:[DB00480 DB00346] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0007275| multicellular organismal development ADRA1D;TNFSF11;ADRA1B GO:0045987| positive regulation of smooth muscle contraction ADRA1A;ADRA1B;PTGS2;ADRA1D GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction ADRA1A;ADRA1B;PTGS2;ADRA1D GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA1D GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0007568| aging PTGS2;ADRA1A 38213:[DB00480 DB04883] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04883|Darusentan EDNRA common genes common pathways GO:0008217| regulation of blood pressure EDNRA;PTGS2 38214:[DB00480 DB00878] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00878|Chlorhexidine HNMT;cat common genes common pathways 38215:[DB00480 DB11586] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP2C9;CYP3A4 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLCO1B1;SLCO2B1 GO:1901529| ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP3A7;CYP3A5;PTGS2;CYP2C19;CYP2B6;CYP2C9;CYP2D6;CYP2A6;CYP3A4;CYP3A43 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 38216:[DB00480 DB07621] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07621|(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2A6 38217:[DB00480 DB11429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11429|Mibolerone AR common genes common pathways GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0006810| transport AR;ABCB1 38218:[DB00480 DB05466] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05466|R673 TACR1 common genes common pathways GO:0032355| response to estradiol stimulus TACR1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;TACR1 GO:0014070| response to organic cyclic compound TACR1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0008217| regulation of blood pressure TACR1;PTGS2 GO:0019233| sensory perception of pain PTGS2;TACR1 GO:0006954| inflammatory response PTGS2;TACR1 38219:[DB00480 DB05752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05752|ALKS 27 CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 38220:[DB00480 DB07804] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07804|5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 38221:[DB00480 DB04805] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04805|Virginiamycin S1 RPL37 common genes common pathways 38222:[DB00480 DB06460] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06460|Enrasentan EDNRA;EDNRB common genes common pathways GO:0008217| regulation of blood pressure EDNRB;PTGS2;EDNRA GO:0014070| response to organic cyclic compound PTGS2;EDNRB GO:0019722| calcium-mediated signaling TNFSF11;EDNRB GO:0019233| sensory perception of pain PTGS2;EDNRB GO:0007568| aging EDNRB;PTGS2 GO:0008284| positive regulation of cell proliferation EDNRB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;EDNRB GO:0032496| response to lipopolysaccharide PTGS2;EDNRB 38223:[DB00480 DB01019] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 38224:[DB00480 DB13800] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0055085| transmembrane transport ABCB1;CALM1 GO:0010033| response to organic substance PTGS2;CASQ1 38225:[DB00480 DB04527] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04527|Beta-Hydroxyasparagine MASP2 common genes common pathways 38226:[DB00480 DB08491] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08491|N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE MMP1 common genes common pathways 38227:[DB00480 DB08613] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;HDAC4;PTGS2 GO:0006954| inflammatory response HDAC4;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;TNFSF11 GO:0071260| cellular response to mechanical stimulus HDAC4;PTGS2 GO:0042493| response to drug PTGS2;HDAC4;ABCB1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HDAC4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC4;TNFSF11 GO:0008284| positive regulation of cell proliferation HDAC4;PTGS2 38228:[DB00480 DB01496] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0006810| transport GABRA3;GABRA5;GABRA4;GABRA6;GRIK2;GABRA1;ABCB1 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0019233| sensory perception of pain PTGS2;CHRNA4 GO:0007613| memory CHRNA7;PTGS2 38229:[DB00480 DB05194] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05194|KB002 CSF2RA;CSF2;CSF2RA common genes common pathways GO:0006955| immune response CSF2;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;CSF2 GO:0019221| cytokine-mediated signaling pathway CSF2RA;TNFSF11 GO:0042127| regulation of cell proliferation CSF2;PTGS2 GO:0008284| positive regulation of cell proliferation CSF2;PTGS2 38230:[DB00480 DB11637] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2 GO:0006954| inflammatory response ORM1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38231:[DB00480 DB07384] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07384|1-ACETYL-2-CARBOXYPIPERIDINE ATP5B common genes common pathways GO:0006629| lipid metabolic process PTGS2;ATP5B GO:0001525| angiogenesis PTGS2;ATP5B 38232:[DB00480 DB13994] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways GO:0006810| transport ABCB1;GABRA3 38233:[DB00480 DB07712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07712|3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL ESR1;NCOA2 common genes common pathways GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;NCOA2 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 38234:[DB00480 DB07798] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07798|(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 38235:[DB00480 DB00414] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways GO:0019371| cyclooxygenase pathway PTGS2;CBR1 GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process CBR1;PTGS2;CYP2C9 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 38236:[DB00480 DB02670] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02670|4-Deoxy-Alpha-D-Glucose SMARCA5 common genes common pathways GO:1990830| TNFSF11;SMARCA5 38237:[DB00480 DB02755] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02755|1-3 Sugar Ring of Pentamannosyl 6-Phosphate M6PR common genes common pathways 38238:[DB00480 DB00565] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00565|Cisatracurium CHRNA2 common genes common pathways 38239:[DB00480 DB06925] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06925|3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE LCK common genes common pathways GO:0042127| regulation of cell proliferation LCK;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;LCK GO:0042493| response to drug PTGS2;LCK;ABCB1 GO:0050870| positive regulation of T cell activation TNFSF11;LCK 38240:[DB00480 DB08502] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08502|Capravirine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38241:[DB00480 DB05685] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05685|FX06 CDH5 common genes CDH5 common pathways GO:1903142| CDH5 GO:0001955| blood vessel maturation CDH5 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0007155| cell adhesion CDH5 GO:0007156| homophilic cell adhesion CDH5 GO:0050728| negative regulation of inflammatory response CDH5 GO:0034332| adherens junction organization CDH5 GO:0098609| CDH5 GO:2000114| regulation of establishment of cell polarity CDH5 GO:0007043| cell-cell junction assembly CDH5 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5 38242:[DB00480 DB00989] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00989|Rivastigmine ACHE;BCHE;CYP3A4 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007155| cell adhesion ACHE;CDH5 GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug PTGS2;BCHE;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 38243:[DB00480 DB00494] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0014070| response to organic cyclic compound COMT;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0042493| response to drug PTGS2;COMT;ABCB1 GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0007612| learning COMT;PTGS2 38244:[DB00480 DB01548] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0009314| response to radiation PTGS2;OPRK1;OPRM1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TRIM13;TNFSF11 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TRIM13;TNFSF11 GO:0010942| positive regulation of cell death TRIM13;PTGS2 GO:0006955| immune response OPRD1;TNFSF11;OPRK1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process TRIM13;CRBN GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0016567| protein ubiquitination TRIM13;CRBN 38245:[DB00480 DB06148] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0032355| response to estradiol stimulus SLC6A4;CYP1A2;PTGS2 GO:0007568| aging HTR2A;SLC6A3;ADRA1A;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLC6A4 GO:0043406| positive regulation of MAP kinase activity HTR2B;HTR2A;ADRA2A;TNFSF11 GO:0010033| response to organic substance CYP1A2;SLC6A4;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007612| learning DRD5;DRD3;DRD1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11;DRD3 GO:0008284| positive regulation of cell proliferation HTR2B;PTGS2;HTR1A;HTR2A;ADRA1D;DRD3;ADRA2A GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0042493| response to drug DRD3;ABCB1;SLC6A4;HTR2C;CYP1A2;SLC6A2;HTR2B;PTGS2;SLC6A3;ADRA1A;DRD2;HTR2A;DRD1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6;CYP2B6;CYP1A2 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0007613| memory HRH1;SLC6A4;DRD1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;ADRA1A;PTGS2;ADRA1B;ADRA2C;HRH1;ADRA1D GO:0014070| response to organic cyclic compound PTGS2;SLC6A3;CYP1A2 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;ADRA1A;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0019233| sensory perception of pain PTGS2;HTR2A;OPRK1 GO:0009314| response to radiation OPRK1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2D6;CYP3A4 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0006954| inflammatory response HRH1;HRH4;PTGS2 GO:0006955| immune response OPRK1;TNFSF11 38246:[DB00480 DB12093] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007613| memory PTGS2;DRD1 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0007612| learning PTGS2;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug DRD2;DRD1;PTGS2;ABCB1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 38247:[DB00480 DB11256] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11256|Levomefolic acid MTR;SLC46A1;SLC19A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC46A1 38248:[DB00480 DB00315] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;MAOA;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;HTR1B;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 38249:[DB00480 DB08224] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08224|(1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL CES1 common genes common pathways 38250:[DB00480 DB11064] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;AR;PGR GO:0060749| mammary gland alveolus development AR;ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0006810| transport ABCB1;AR 38251:[DB00480 DB03152] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03152|B-2-Octylglucoside polA;aqpZ;TGM3;aqpZ;petB;petA;RHO common genes common pathways 38252:[DB00480 DB05044] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05044|PSN357 PYGL common genes common pathways 38253:[DB00480 DB03926] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03926|5-Alpha-Androstane-3-Beta,17-Alpha-Diol SHBG common genes common pathways 38254:[DB00480 DB07720] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0019233| sensory perception of pain CHRNA4;PTGS2;CHRNB2 GO:0007613| memory CHRNB2;PTGS2;CHRNA7 GO:0007612| learning PTGS2;CHRNB2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0006979| response to oxidative stress PTGS2;CHRNA4 38255:[DB00480 DB07694] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07694|2,5-dichloro-N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport ABCB1;TTR 38256:[DB00480 DB05201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05201|V24343 CNR1 common genes common pathways GO:0007568| aging PTGS2;CNR1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2 GO:0007613| memory CNR1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain CNR1;PTGS2 38257:[DB00480 DB05451] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05451|P54 NFKB2;NFKB1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0006954| inflammatory response NFKB2;PTGS2;NFKB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB1;NFKB2;TNFSF11 GO:0007568| aging NFKB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NFKB1;NFKB2 GO:0043066| negative regulation of apoptotic process NFKB1;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;NFKB2 GO:0032496| response to lipopolysaccharide PTGS2;NFKB2 GO:0050728| negative regulation of inflammatory response CDH5;NFKB1 38258:[DB00480 DB03566] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0055114| oxidation-reduction process TXNRD1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC22A4 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0098869| PTGS2;TXNRD1 38259:[DB00480 DB09331] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09331|Daratumumab CD38 common genes common pathways GO:0045907| positive regulation of vasoconstriction CD38;PTGS2 GO:0032355| response to estradiol stimulus CD38;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;CD38 GO:0043066| negative regulation of apoptotic process CD38;PTGS2 GO:0042493| response to drug ABCB1;CD38;PTGS2 38260:[DB00480 DB01337] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01337|Pancuronium CHRNA2;CHRM2;CHRM3;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0006855| drug transmembrane transport SLC22A2;SLC22A1;ABCB1 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0007612| learning BCHE;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;BCHE 38261:[DB00480 DB06111] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06111|AB192 MPO common genes common pathways GO:0055114| oxidation-reduction process MPO;PTGS2 GO:0043066| negative regulation of apoptotic process MPO;PTGS2 GO:0032496| response to lipopolysaccharide MPO;PTGS2 GO:0006979| response to oxidative stress MPO;PTGS2 GO:0007568| aging MPO;PTGS2 38262:[DB00480 DB04783] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04783|Sphinxolide B ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 38263:[DB00480 DB01074] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound CPT1A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CPT2;CYP2D6;CPT1A GO:0051260| protein homooligomerization CPT1A;TNFSF11 GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0006631| fatty acid metabolic process CPT1A;CPT2;PTGS2 GO:0042493| response to drug CPT1A;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;CYP2D6;PTGS2 38264:[DB00480 DB01977] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01977|6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0042127| regulation of cell proliferation PLAU;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;PLAU 38265:[DB00480 DB04915] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04915|Idronoxil ENOX2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ENOX2 38266:[DB00480 DB04997] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04997|ATL1102 ITGA4 common genes common pathways GO:0007155| cell adhesion CDH5;ITGA4 38267:[DB00480 DB05091] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05091|M0002 AVPR2 common genes common pathways GO:0034097| response to cytokine stimulus AVPR2;PTGS2 GO:0008284| positive regulation of cell proliferation AVPR2;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;AVPR2 38268:[DB00480 DB00704] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00704|Naltrexone OPRD1;OPRM1;OPRK1;SIGMAR1;UGT1A1 common genes common pathways GO:0019233| sensory perception of pain OPRK1;OPRM1;PTGS2;OPRD1 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11;OPRD1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2;UGT1A1 GO:0042493| response to drug PTGS2;UGT1A1;ABCB1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 38269:[DB00480 DB06595] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0043065| positive regulation of apoptotic process PDGFRB;PTGS2 GO:0009314| response to radiation KIT;PTGS2 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP1A2;CYP3A4;PTGS2 GO:0007275| multicellular organismal development TNFSF11;PDGFRB;PDGFRA;KDR GO:0001525| angiogenesis PRKCA;PTGS2;KDR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0006954| inflammatory response KIT;PTGS2 GO:0030154| cell differentiation KDR;FLT3;TNFSF11 GO:0014070| response to organic cyclic compound PDGFRB;CYP1A2;PTGS2 GO:0043066| negative regulation of apoptotic process PDGFRB;KDR;PTGS2 GO:0008284| positive regulation of cell proliferation PDGFRA;PTGS2;KIT;KDR;FLT3;PDGFRB GO:0007155| cell adhesion PRKCA;CDH5 GO:0042127| regulation of cell proliferation PTGS2;KIT GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PDGFRB GO:0010243| response to organic nitrogen PTGS2;CYP2E1;FLT3 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PDGFRB;PDGFRA;KIT GO:0019221| cytokine-mediated signaling pathway FLT3;TNFSF11;KIT GO:0042493| response to drug PTGS2;CYP2E1;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP2B6;CYP2D6;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP2E1;CYP3A7;CYP2C8;CYP2C19;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;PDGFRB;CYP1A2 GO:0045780| positive regulation of bone resorption TNFSF11;PRKCA GO:0007568| aging PTGS2;PDGFRB GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0043406| positive regulation of MAP kinase activity KIT;PDGFRB;TNFSF11;FLT3 38270:[DB00480 DB07334] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07334|N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE KDR common genes common pathways GO:0008284| positive regulation of cell proliferation KDR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0030154| cell differentiation KDR;TNFSF11 GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0001525| angiogenesis KDR;PTGS2 GO:0007275| multicellular organismal development TNFSF11;KDR 38271:[DB00480 DB08172] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08172|(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0042493| response to drug DHODH;PTGS2;ABCB1 38272:[DB00480 DB01962] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01962|Phosphonotyrosine HCK;SRC;KIT common genes common pathways GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0034332| adherens junction organization CDH5;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;KIT;SRC GO:0019221| cytokine-mediated signaling pathway TNFSF11;KIT;HCK GO:0042127| regulation of cell proliferation SRC;KIT;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;SRC;HCK GO:0008284| positive regulation of cell proliferation PTGS2;KIT;HCK GO:0007155| cell adhesion CDH5;HCK;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;KIT;SRC GO:0098609| CDH5;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:1902533| SRC;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;TNFSF11 GO:0006954| inflammatory response KIT;PTGS2;HCK GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0050727| regulation of inflammatory response PTGS2;HCK GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0009314| response to radiation KIT;PTGS2 GO:0030154| cell differentiation HCK;TNFSF11 GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0070542| response to fatty acid SRC;PTGS2 38273:[DB00480 DB01835] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01835|4r-Fluoro-N6-Ethanimidoyl-L-Lysine NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 38274:[DB00480 DB03419] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03419|Uracil DPYD;UCKL1;udg common genes common pathways GO:0055114| oxidation-reduction process DPYD;PTGS2 38275:[DB00480 DB01296] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0046330| positive regulation of JNK cascade TNFSF11;TNF GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0032496| response to lipopolysaccharide NFKB2;PTGS2 GO:0034097| response to cytokine stimulus NFKB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TNF;NFKB2 GO:0008284| positive regulation of cell proliferation IFNG;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;MMP9 GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0007568| aging NFKB2;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;TNF;IFNG GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2;IFNG GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0010033| response to organic substance TNF;PTGS2 GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0001503| ossification MMP9;TNFSF11 GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0045672| positive regulation of osteoclast differentiation IFNG;TNF;TNFSF11 GO:0043065| positive regulation of apoptotic process MMP9;PTGS2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;NFKB2;TNFSF11 GO:0006954| inflammatory response PTGS2;NFKB2;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0006955| immune response IFNG;TNF;TNFSF11 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0007566| embryo implantation MMP9;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 38276:[DB00480 DB12866] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8 38277:[DB00480 DB02974] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02974|4-(4-Chlorophenyl)Imidazole CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2B6 38278:[DB00480 DB00849] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0006810| transport GABRA5;GABRA3;GRIK2;GABRA6;GABRA4;GABRA1;ABCB1 GO:0055114| oxidation-reduction process CYP2B6;PTGS2;CYP2C19 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0007613| memory PTGS2;CHRNA7 GO:0019233| sensory perception of pain PTGS2;CHRNA4 38279:[DB00480 DB04674] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0008217| regulation of blood pressure EDNRA;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AKR1C1 GO:0006810| transport TTR;ABCB1 GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0051260| protein homooligomerization AKR1C1;TNFSF11 38280:[DB00480 DB13150] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13150|Coagulation factor VII human F3;F10;F9 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F3;TNFSF11;F10 GO:0019221| cytokine-mediated signaling pathway TNFSF11;F3 38281:[DB00480 DB04827] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G4A GO:0042127| regulation of cell proliferation PLA2G4A;PTGS2 GO:0032496| response to lipopolysaccharide MPO;PTGS2 GO:0043066| negative regulation of apoptotic process MPO;PTGS2 GO:0055114| oxidation-reduction process MPO;PTGS2;AOX1 GO:0007568| aging PTGS2;MPO GO:0006979| response to oxidative stress MPO;PTGS2 38282:[DB00480 DB00521] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 38283:[DB00480 DB06842] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06842|(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one PDE4A;PDE4D common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity TNFSF11;PDE4D 38284:[DB00480 DB00549] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0006810| transport ABCG2;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;CYP2C9;CYP3A4;CYP2E1;PTGS1;PTGS2;CYP2C8;CYP2C19 GO:0042493| response to drug CYP2E1;PTGS2;ABCG2;CYP1A2;ABCB1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;PTGS2;PTGS1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 38285:[DB00480 DB05419] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05419|ADX-10061 CALY common genes common pathways 38286:[DB00480 DB07695] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07695|N-(3,5-dibromo-4-hydroxyphenyl)-4-hydroxy-3,5-dimethylbenzamide TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TNFSF11;TTR 38287:[DB00480 DB07851] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07851|(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 38288:[DB00480 DB09296] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09296|Ombitasvir CYP2C8;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0006810| transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:1901529| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2;ABCG2 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 38289:[DB00480 DB00852] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0043065| positive regulation of apoptotic process JUN;ATF4;TNF;PTGS2;ATF6 GO:0045672| positive regulation of osteoclast differentiation TNF;FOS;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0009314| response to radiation JUN;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;ATF4 GO:0001525| angiogenesis PTGS2;JUN GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0007275| multicellular organismal development TNFSF11;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0006954| inflammatory response PTGS2;TNF;FOS GO:0006955| immune response TNFSF11;IL2;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ATF2;TNF GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF GO:0034644| cellular response to UV PTGS2;ATF4 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0007613| memory PTGS2;SLC6A4 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0008285| negative regulation of cell proliferation JUN;ADRA1A;PTGS2;CDH5;ATF5 GO:0014070| response to organic cyclic compound PTGS2;ATF1;JUN;SLC6A3;FOS GO:0008284| positive regulation of cell proliferation ATF3;JUN;PTGS2;IL2;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;ATF1;ATF4;JUN;FOS;ATF3;NFATC1;ATF5;ATF2;ATF6;ADRB2;TNFSF11;IL2 GO:0043066| negative regulation of apoptotic process IL2;ATF5;JUN;PTGS2 GO:0007155| cell adhesion IL2;CDH5 GO:0034097| response to cytokine stimulus FOS;JUN;PTGS2 GO:0042127| regulation of cell proliferation JUN;PTGS2;TNF GO:0007612| learning PTGS2;JUN GO:0032496| response to lipopolysaccharide JUN;FOS;PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;TNF GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0050728| negative regulation of inflammatory response IL2;CDH5 GO:0048661| positive regulation of smooth muscle cell proliferation JUN;TNF;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0042493| response to drug SLC6A3;ADRA1A;FOS;JUN;SLC6A2;PTGS2;ABCB1;SLC6A4 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;MAOA;CYP2D6 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0010469| regulation of receptor activity IL2;TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0007568| aging PTGS2;FOS;SLC6A3;ADRA1A;JUN GO:0006810| transport SLC6A2;ABCB1 GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNF;ADRA2A;TNFSF11 GO:0010033| response to organic substance JUN;PTGS2;TNF;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A3;SLC6A2;ABCB1;SLC6A4 GO:0007179| transforming growth factor beta receptor signaling pathway JUN;FOS;CDH5 38290:[DB00480 DB03083] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03083|IC261 CSNK1G2 common genes common pathways 38291:[DB00480 DB07765] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07765|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHRS4L1 38292:[DB00480 DB02773] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02773|(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid PTGS1 common genes common pathways GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 38293:[DB00480 DB05022] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A 38294:[DB00480 DB06972] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06972|7A-[(4-cyanophenyl)methyl]-6-(3,5-dichlorophenyl)-5-oxo-2,3,5,7A-tetrahydro-1H-pyrrolo[1,2-A]pyrrole-7-carbonitrile ITGAL common genes common pathways GO:0098609| ITGAL;CDH5 GO:0007155| cell adhesion ITGAL;CDH5 GO:0006954| inflammatory response ITGAL;PTGS2 38295:[DB00480 DB00192] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00192|Indecainide SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 38296:[DB00480 DB00534] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC12A1 GO:0006810| transport SLC12A1;ABCB1 GO:0055114| oxidation-reduction process ALDH5A1;PTGS2 38297:[DB00480 DB02215] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02215|Furoyl-Leucine ADAM28 common genes common pathways 38298:[DB00480 DB08299] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08299|4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid PDE4A;PDE4B;PDE4D common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity PDE4D;TNFSF11 38299:[DB00480 DB05210] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0043066| negative regulation of apoptotic process PIK3R1;PRKDC;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PIK3R1;PRKDC;PIK3R2;TNFSF11 GO:0016567| protein ubiquitination PRKDC;CRBN GO:0051897| positive regulation of protein kinase B signaling cascade PIK3R2;TNFSF11;MTOR;PIK3R1 GO:0048661| positive regulation of smooth muscle cell proliferation MTOR;PTGS2 GO:0071456| cellular response to hypoxia MTOR;PTGS2 GO:0045670| regulation of osteoclast differentiation TNFSF11;MTOR GO:0045429| positive regulation of nitric oxide biosynthetic process MTOR;PTGS2 GO:0043065| positive regulation of apoptotic process PRKDC;PTGS2 GO:0010942| positive regulation of cell death MTOR;PTGS2 GO:0034644| cellular response to UV PTGS2;PIK3R1 38300:[DB00480 DB01588] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006810| transport GABRA1;GABRB3;ABCB1;GABRG2;GABRA5;GABRA3;GABRB2;GABRR2;GABRD;GABRB1;GABRA6;GABRR1;GABRA4 GO:0042493| response to drug ABCB1;GABRG3;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38301:[DB00480 DB00963] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes PTGS2 common pathways GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:1902219| PTGS2 GO:0007568| aging PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:1990776| PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 38302:[DB00480 DB07872] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07872|5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 38303:[DB00480 DB00574] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00574|Fenfluramine SLC6A4;HTR2B;HTR2C;HTR2A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A;SLC6A4 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR2A;HTR2B;PTGS2 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0042493| response to drug HTR2C;ABCB1;SLC6A4;HTR2A;HTR2B;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0007568| aging HTR2A;PTGS2 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A;HTR2B GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 38304:[DB00480 DB01819] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01819|Phosphoenolpyruvate aroG;kdsA;ENO3;PCK1;kdsA;SLCO2A1 common genes common pathways GO:0007568| aging PCK1;ENO3;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;PCK1 GO:0055085| transmembrane transport ABCB1;SLCO2A1 GO:0032496| response to lipopolysaccharide PCK1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ENO3 GO:0006629| lipid metabolic process PTGS2;PCK1 38305:[DB00480 DB05305] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05305|Cintredekin Besudotox IL13 common genes common pathways GO:0071260| cellular response to mechanical stimulus IL13;PTGS2 GO:0006954| inflammatory response PTGS2;IL13 GO:0006955| immune response TNFSF11;IL13 GO:0032496| response to lipopolysaccharide PTGS2;IL13 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;IL13 GO:0010469| regulation of receptor activity TNFSF11;IL13 38306:[DB00480 DB01871] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01871|[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways 38307:[DB00480 DB06138] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06138|IRL-1620 EDNRB common genes common pathways GO:0032496| response to lipopolysaccharide EDNRB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;EDNRB GO:0008284| positive regulation of cell proliferation PTGS2;EDNRB GO:0007568| aging PTGS2;EDNRB GO:0019233| sensory perception of pain EDNRB;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;EDNRB GO:0014070| response to organic cyclic compound EDNRB;PTGS2 GO:0008217| regulation of blood pressure EDNRB;PTGS2 38308:[DB00480 DB07235] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07235|N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE PRKACA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA GO:0034605| cellular response to heat PRKACA;PTGS2 38309:[DB00480 DB00289] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0019233| sensory perception of pain GRIN1;PTGS2;GRIN2A GO:0043065| positive regulation of apoptotic process GRIN1;PTGS2;GRIN2A GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0019722| calcium-mediated signaling GRIN2C;GRIN1;GRIN2B;GRIN2A;GRIN2D;TNFSF11 GO:0007613| memory GRIN2A;SLC6A4;PTGS2;GRIN1 GO:0042493| response to drug ABCB1;GRIN2A;SLC6A4;SLC6A2;PTGS2;SLC6A3 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;PTGS2;CYP2C19 GO:0007612| learning GRIN2A;PTGS2;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;GRIN1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLC6A4 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0006810| transport GRIN2A;GRIN2B;ABCB1;SLC6A2;GRIN2C GO:0007568| aging PTGS2;SLC6A3 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 38310:[DB00480 DB07963] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07963|N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINE TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport ABCB1;TTR 38311:[DB00480 DB11491] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11491|Sarafloxacin CYP1A2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 38312:[DB00480 DB02635] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02635|N-[O-Phosphono-Pyridoxyl]-Isoleucine BCAT2 common genes common pathways GO:1990830| TNFSF11;BCAT2 38313:[DB00480 DB06751] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0055085| transmembrane transport ABCB1;CACNA1C 38314:[DB00480 DB04926] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04926|Neramexane GRIN3A common genes common pathways 38315:[DB00480 DB07132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07132|1-{2-OXO-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-5-YL}UREA PDPK1 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;PDPK1 38316:[DB00480 DB01650] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;ABCB1 38317:[DB00480 DB03928] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03928|Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol CTH common genes common pathways GO:1990830| TNFSF11;CTH GO:0043066| negative regulation of apoptotic process PTGS2;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTH;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CTH 38318:[DB00480 DB07006] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07006|9-HYDROXY-6-(3-HYDROXYPROPYL)-4-(2-METHOXYPHENYL)PYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE WEE1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle WEE1;ABCB1 38319:[DB00480 DB04392] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04392|Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] NQO1;azoR common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;NQO1 GO:0007568| aging PTGS2;NQO1 GO:0006979| response to oxidative stress NQO1;PTGS2 GO:0043066| negative regulation of apoptotic process NQO1;PTGS2 GO:0055114| oxidation-reduction process NQO1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;NQO1 38320:[DB00480 DB03611] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03611|L-2-amino-4-methoxy-cis-but-3-enoic acid MAT1A common genes common pathways 38321:[DB00480 DB00150] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0060749| mammary gland alveolus development TNFSF11;TPH1 GO:0032496| response to lipopolysaccharide IDO1;PTGS2 GO:0055114| oxidation-reduction process TPH1;TDO2;IDO1;TPH2;PTGS2 GO:0006810| transport ABCB1;SLC16A2 GO:0055085| transmembrane transport SLC16A2;SLC16A10;ABCB1 GO:0043065| positive regulation of apoptotic process IDO1;PTGS2 GO:0001525| angiogenesis PTGS2;WARS GO:0006954| inflammatory response PTGS2;IDO1 GO:0051384| response to glucocorticoid stimulus PTGS2;TPH2 GO:0008285| negative regulation of cell proliferation WARS;CDH5;PTGS2 38322:[DB00480 DB02825] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02825|Methylphosphonic Acid Ester Group ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 38323:[DB00480 DB02854] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02854|Aetiocholanolone SULT2A1;HSD17B11;IGHG2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HSD17B11 GO:0006629| lipid metabolic process PTGS2;SULT2A1;HSD17B11 38324:[DB00480 DB06534] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06534|Thrombopoietin MPL common genes common pathways GO:0019221| cytokine-mediated signaling pathway MPL;TNFSF11 38325:[DB00480 DB05166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05166|APD668 GPR119 common genes common pathways 38326:[DB00480 DB01288] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0007568| aging ADRB3;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0050873| brown fat cell differentiation ADRB2;ADRB3;ADRB1;PTGS2 38327:[DB00480 DB04695] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04695|Farnesyl thiopyrophosphate ispU;GGPS1;MVK common genes common pathways GO:0006629| lipid metabolic process MVK;PTGS2 GO:0050728| negative regulation of inflammatory response MVK;CDH5 38328:[DB00480 DB12077] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12077|Urelumab TNFRSF9 common genes common pathways GO:0032496| response to lipopolysaccharide TNFRSF9;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;TNFRSF9 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFRSF9;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;TNFRSF9 GO:0006954| inflammatory response TNFRSF9;PTGS2 GO:0006955| immune response TNFSF11;TNFRSF9 GO:0008285| negative regulation of cell proliferation CDH5;TNFRSF9;PTGS2 38329:[DB00480 DB06155] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways GO:0007613| memory PTGS2;CNR1 GO:0045453| bone resorption GPR55;TNFSF11 GO:0019233| sensory perception of pain CNR1;PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CNR1 GO:0007568| aging CNR1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CNR1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 38330:[DB00480 DB06274] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0019233| sensory perception of pain PTGS2;OPRD1;OPRK1;OPRM1 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0006955| immune response OPRD1;OPRK1;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 38331:[DB00480 DB06977] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06977|(2S)-1-{[5-(1H-Indazol-5-yl)-3-pyridinyl]oxy}-3-(7aH-indol-3-yl)-2-propanamine PRKACA common genes common pathways GO:0034605| cellular response to heat PRKACA;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA 38332:[DB00480 DB11431] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0042493| response to drug ABCB1;ABCG2;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A7;PTGS2;CYP3A4;CYP3A43 GO:0099040| ABCB1 GO:1901529| ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1;ABCG2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 38333:[DB00480 DB05042] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05042|SGS518 HTR6 common genes common pathways 38334:[DB00480 DB05688] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0006810| transport ABCB1;SLC6A2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A2 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0042493| response to drug ABCB1;SLC6A4;SLC6A2;PTGS2 GO:0007613| memory SLC6A4;PTGS2 38335:[DB00480 DB04958] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04958|Epratuzumab CD22 common genes common pathways GO:0007155| cell adhesion CD22;CDH5 38336:[DB00480 DB04166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04166|Anthranilic acid IL4I1;DAO common genes common pathways GO:0055114| oxidation-reduction process IL4I1;DAO;PTGS2 38337:[DB00480 DB00047] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00047|Insulin Glargine INSR;IGF1R common genes common pathways GO:0007613| memory PTGS2;INSR GO:0006955| immune response IGF1R;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;PTGS2 GO:0009887| organ morphogenesis TNFSF11;INSR GO:0007612| learning INSR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;IGF1R GO:0008284| positive regulation of cell proliferation INSR;IGF1R;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 38338:[DB00480 DB01483] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP3A4 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0006810| transport GABRA4;GABRA6;GRIK2;GABRA3;GABRA5;ABCB1;GABRA1 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0019233| sensory perception of pain PTGS2;CHRNA4 GO:0007613| memory PTGS2;CHRNA7 38339:[DB00480 DB12890] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12890|Dihydrexidine DRD1 common genes common pathways GO:0007613| memory DRD1;PTGS2 GO:0042493| response to drug ABCB1;DRD1;PTGS2 GO:0007612| learning DRD1;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 38340:[DB00480 DB00130] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TGM2 GO:0043065| positive regulation of apoptotic process PTGS2;TGM2 GO:0055085| transmembrane transport ABCB1;SLC38A3;SLC16A10 GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:1990830| GFPT2;TNFSF11 GO:0006810| transport SLC7A8;ABCB1 GO:0051260| protein homooligomerization GLUL;TNFSF11;TGM2 GO:0042493| response to drug PTGS2;PPAT;CTPS1;ABCB1;PFAS GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TGM2 GO:0043066| negative regulation of apoptotic process ASNS;PTGS2 38341:[DB00480 DB08413] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08413|METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER IGKC;ALPP common genes common pathways GO:0006955| immune response TNFSF11;IGKC 38342:[DB00480 DB06579] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0006810| transport GABRA5;GABRA3;GABRA6;GABRA4;GABRA1;ABCB1;GABRG2 GO:0042493| response to drug PTGS2;GABRG3;ABCB1 38343:[DB00480 DB00459] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00459|Acitretin RXRA;RARA;RARB;RARG;RXRB;RXRG;RBP1;CYP26A1;ALB common genes common pathways GO:0007566| embryo implantation PTGS2;RXRA GO:0008285| negative regulation of cell proliferation CDH5;RARB;RARG;RARA;PTGS2 GO:0043065| positive regulation of apoptotic process RARG;PTGS2;RARB GO:0032355| response to estradiol stimulus PTGS2;RARA GO:0098869| PTGS2;ALB GO:1990830| TNFSF11;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARB;RXRA;TNFSF11;RXRB;RARA;RARG;RXRG GO:0008284| positive regulation of cell proliferation RARB;RARG;RARA;PTGS2 GO:0043066| negative regulation of apoptotic process RARB;PTGS2;RARA;ALB;RARG GO:0034097| response to cytokine stimulus RARA;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP26A1 38344:[DB00480 DB07427] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07427|2-[(2-methoxy-5-methylphenoxy)methyl]pyridine HBA1;HBB common genes common pathways GO:0098869| PTGS2;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;PTGS2 GO:0008217| regulation of blood pressure HBB;PTGS2 GO:0010942| positive regulation of cell death HBB;PTGS2;HBA1 38345:[DB00480 DB03525] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03525|RU79073 SRC common genes common pathways GO:1902533| SRC;TNFSF11 GO:0098609| SRC;CDH5 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0007155| cell adhesion CDH5;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042493| response to drug ABCB1;PTGS2;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0070542| response to fatty acid PTGS2;SRC GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 38346:[DB00480 DB00117] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00117|Histidine HDC;HARS;SLC38A3;HAL;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC38A3;SLC16A10 38347:[DB00480 DB03976] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03976|Phosphorylisopropane PRSS1;PRSS2;CTRB1;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 38348:[DB00480 DB01551] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 38349:[DB00480 DB04472] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04472|(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol LGALS9 common genes common pathways GO:0006954| inflammatory response PTGS2;LGALS9 GO:0051092| positive regulation of NF-kappaB transcription factor activity LGALS9;TNFSF11 GO:0070371| ERK1 and ERK2 cascade LGALS9;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;LGALS9 GO:0071636| positive regulation of transforming growth factor beta production PTGS2;LGALS9 GO:0032496| response to lipopolysaccharide LGALS9;PTGS2 38350:[DB00480 DB06749] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06749|ginsenoside Rb1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3 38351:[DB00480 DB00978] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0006810| transport ABCB1;ABCC2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCC2;SLC22A5 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide ABCC2;CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;ABCC2;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCC2;SLC22A5 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A 38352:[DB00480 DB06714] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC18A2 38353:[DB00480 DB08210] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08210|2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE GCK common genes common pathways 38354:[DB00480 DB01463] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01463|Fencamfamine SLC6A3 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0042493| response to drug PTGS2;SLC6A3;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0007568| aging PTGS2;SLC6A3 38355:[DB00480 DB04929] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04929|DG031 ALOX5AP common genes common pathways GO:0019372| lipoxygenase pathway ALOX5AP;PTGS2 38356:[DB00480 DB04602] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04602|PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE RPL37 common genes common pathways 38357:[DB00480 DB01561] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01561|Androstanedione HSD17B1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;HSD17B1 GO:0055114| oxidation-reduction process HSD17B1;PTGS2 38358:[DB00480 DB08597] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08597|6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine ACVR1;FKBP1A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ACVR1 GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;ACVR1;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A 38359:[DB00480 DB07605] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07605|2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 38360:[DB00480 DB08733] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08733|(2R,3R)-N^1^-[(1S)-2,2-DIMETHYL-1-(METHYLCARBAMOYL)PROPYL]-N^4^-HYDROXY-2-(2-METHYLPROPYL)-3-{[(1,3-THIAZOL-2-YLCARBONYL)AMINO]METHYL}BUTANEDIAMIDE ADAM28 common genes common pathways 38361:[DB00480 DB03917] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03917|N-Ethyl Retinamide RBP4 common genes common pathways 38362:[DB00480 DB05290] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05290|SPP 301 EDNRA common genes common pathways GO:0008217| regulation of blood pressure EDNRA;PTGS2 38363:[DB00480 DB09142] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09142|Sincalide SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCB1 38364:[DB00480 DB06342] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0051897| positive regulation of protein kinase B signaling cascade CD19;TNFSF11 38365:[DB00480 DB04299] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0042307| positive regulation of protein import into nucleus TPR;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;GOT1 GO:0034605| cellular response to heat PTGS2;TPR 38366:[DB00480 DB03807] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03807|1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4B common genes common pathways 38367:[DB00480 DB07194] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways GO:0045780| positive regulation of bone resorption TNFSF11;SYK GO:0009887| organ morphogenesis TNFSF11;SYK GO:0001525| angiogenesis PTGS2;SYK GO:0006954| inflammatory response PTGS2;SYK GO:0007257| activation of JUN kinase activity SYK;TNFSF11 38368:[DB00480 DB09108] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09108|Simoctocog Alfa VWF common genes common pathways GO:0051260| protein homooligomerization VWF;TNFSF11 GO:0007155| cell adhesion VWF;CDH5 38369:[DB00480 DB07423] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07423|(2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide AR common genes common pathways GO:0006810| transport ABCB1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR 38370:[DB00480 DB02323] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02323|EM-1745 HSD17B1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HSD17B1 GO:0006629| lipid metabolic process HSD17B1;PTGS2 38371:[DB00480 DB06984] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06984|(1R,2R,3R,4S,5R)-4-(BENZYLAMINO)-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL MAN2A1 common genes common pathways 38372:[DB00480 DB02542] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02542|(4s)-5-Fluoro-L-Leucine UBB common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade UBB;TNFSF11 GO:0043065| positive regulation of apoptotic process UBB;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;UBB GO:0045944| positive regulation of transcription from RNA polymerase II promoter UBB;TNFSF11 GO:0043066| negative regulation of apoptotic process UBB;PTGS2 GO:0016567| protein ubiquitination UBB;CRBN GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;UBB GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;UBB GO:0000086| G2/M transition of mitotic cell cycle ABCB1;UBB GO:0055085| transmembrane transport UBB;ABCB1 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;UBB 38373:[DB00480 DB01047] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0042307| positive regulation of protein import into nucleus SMO;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0001503| ossification SMO;TNFSF11 GO:0007275| multicellular organismal development SMO;TNFSF11 GO:0043066| negative regulation of apoptotic process SMO;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;SMO;NR3C1 GO:0008284| positive regulation of cell proliferation SMO;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38374:[DB00480 DB04464] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04464|N-Formylmethionine RNASE1;CLPP;RABGGTA;RABGGTB;SERPINC1;B2M;MT-ND1;HLA-B;S100G;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;fmt;S100B;UBC;atpH common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity UBC;TNFSF11 GO:0006955| immune response TNFSF11;B2M;HLA-B GO:0043065| positive regulation of apoptotic process S100B;PTGS2;UBC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;TNFSF11;UBC GO:0014070| response to organic cyclic compound MT-ND1;PTGS2 GO:0007613| memory S100B;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;S100B GO:0055114| oxidation-reduction process MT-CO1;MT-ND1;MT-CO2;PTGS2 GO:0016567| protein ubiquitination UBC;CRBN GO:0042493| response to drug PTGS2;MT-ND1;ABCB1;B2M GO:0008284| positive regulation of cell proliferation PTGS2;S100B GO:0045944| positive regulation of transcription from RNA polymerase II promoter UBC;TNFSF11 GO:0043066| negative regulation of apoptotic process UBC;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle UBC;ABCB1 GO:0055085| transmembrane transport UBC;ABCB1 GO:0007179| transforming growth factor beta receptor signaling pathway UBC;CDH5 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process UBC;CRBN GO:0051260| protein homooligomerization TNFSF11;CLPP GO:0006979| response to oxidative stress PTGS2;MT-CO1 GO:0071456| cellular response to hypoxia PTGS2;S100B GO:0007568| aging PTGS2;MT-CO1 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;UBC 38375:[DB00480 DB02796] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02796|9-Deazainosine PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1;PTGS2 GO:0006955| immune response PNP;TNFSF11 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 38376:[DB00480 DB02162] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02162|5'-O-(N-Ethyl-Sulfamoyl)Adenosine HINT1 common genes common pathways 38377:[DB00480 DB08374] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08374|Phenylalanylmethylchloride CTRB1 common genes common pathways 38378:[DB00480 DB04260] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04260|9-(5,5-Difluoro-5-Phosphonopentyl)Guanine PNP common genes common pathways GO:0006955| immune response PNP;TNFSF11 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0042493| response to drug PNP;ABCB1;PTGS2 38379:[DB00480 DB08357] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08357|1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE ACHE;nagZ common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 38380:[DB00480 DB00010] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00010|Sermorelin GHRHR common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;GHRHR GO:0008284| positive regulation of cell proliferation GHRHR;PTGS2 38381:[DB00480 DB08362] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08362|N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZIN-2-YLAMINO)PHENYL)ACETAMIDE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 38382:[DB00480 DB02049] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02049|2-{4-[4-(4-Chloro-Phenoxy)-Benzenesulfonyl]-Tetrahydro-Pyran-4-Yl}-N-Hydroxy-Acetamide MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13 38383:[DB00480 DB05941] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05941|Leronlimab CCR5 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;CCR5 GO:0006955| immune response CCR5;TNFSF11 GO:0006954| inflammatory response PTGS2;CCR5 38384:[DB00480 DB03589] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03589|Alpha-Ketomalonic Acid ME2 common genes common pathways GO:0055114| oxidation-reduction process ME2;PTGS2 38385:[DB00480 DB00036] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00036|Coagulation factor VIIa Recombinant Human F10;HPN;TFPI;GGCX;F7;F3 common genes common pathways GO:0014070| response to organic cyclic compound F7;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;F7;TFPI GO:0032496| response to lipopolysaccharide PTGS2;TFPI GO:0043066| negative regulation of apoptotic process PTGS2;HPN GO:0051897| positive regulation of protein kinase B signaling cascade F3;TNFSF11;F7;F10 GO:0019221| cytokine-mediated signaling pathway F3;TNFSF11 38386:[DB00480 DB03449] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03449|N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine NOS2;NOS1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0055114| oxidation-reduction process NOS1;PTGS2;NOS2 GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 38387:[DB00480 DB07160] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07160|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 38388:[DB00480 DB07567] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07567|(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL ESR1 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 38389:[DB00480 DB02991] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02991|S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea NOS1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS1 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;TNFSF11 38390:[DB00480 DB03660] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03660|4-Iodo-L-phenylalanine DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 38391:[DB00480 DB06916] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06916|N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 GO:0055114| oxidation-reduction process PTGS2;NOS2 38392:[DB00480 DB12271] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12271|ORE-1001 CPN1;CPN2 common genes common pathways GO:0051384| response to glucocorticoid stimulus CPN1;PTGS2 38393:[DB00480 DB02451] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02451|B-nonylglucoside RHO;AQP1;CLPS;PNLIP;MIP;KCNJ3 common genes common pathways GO:0034644| cellular response to UV PTGS2;AQP1 GO:0071260| cellular response to mechanical stimulus AQP1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CLPS;PNLIP GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process AQP1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;AQP1 GO:0055085| transmembrane transport AQP1;ABCB1;MIP GO:0043066| negative regulation of apoptotic process AQP1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;AQP1 38394:[DB00480 DB03060] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03060|Sri-9662 DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 38395:[DB00480 DB01307] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0007613| memory PTGS2;INSR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;INSR GO:0007612| learning PTGS2;INSR GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;INSR GO:0009887| organ morphogenesis INSR;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR GO:0098869| PTGS2;ALB 38396:[DB00480 DB02093] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02093|5-Phospho-D-Arabinohydroxamic Acid GPI common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPI GO:0001525| angiogenesis PTGS2;GPI GO:0010469| regulation of receptor activity GPI;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;GPI 38397:[DB00480 DB01571] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0006955| immune response OPRD1;OPRK1;TNFSF11 GO:0009314| response to radiation PTGS2;OPRK1;OPRM1 GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRK1;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 38398:[DB00480 DB03367] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03367|PF-00356231 MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 38399:[DB00480 DB00336] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00336|Nitrofural gor;mdh;XDH common genes common pathways GO:0055114| oxidation-reduction process XDH;PTGS2 38400:[DB00480 DB02143] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02143|N-Isopropyl-N'-Hydroxyguanidine NOS1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NOS1 GO:0055114| oxidation-reduction process NOS1;PTGS2 GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 38401:[DB00480 DB00353] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007613| memory DRD1;PTGS2 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042493| response to drug PTGS2;HTR2B;DRD1;ABCB1 GO:0007612| learning DRD1;PTGS2 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2B;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2B 38402:[DB00480 DB01408] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0042493| response to drug ABCB1;BCHE;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0045453| bone resorption TNFSF11;ADRB2 38403:[DB00480 DB02689] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02689|S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine ARG1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;ARG1 GO:0010042| response to manganese ion PTGS2;ARG1 GO:0042493| response to drug ARG1;PTGS2;ABCB1 GO:0007568| aging ARG1;PTGS2 38404:[DB00480 DB00340] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00340|Metixene CHRM1;CHRM4;CHRM5;CHRM2;CHRM3 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 38405:[DB00480 DB08737] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08737|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL ESR1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 38406:[DB00480 DB04343] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04343|Glyoxylic acid glcB;glcB;SLC16A3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A3 38407:[DB00480 DB04478] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04478|Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine SORD common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;SORD GO:0055114| oxidation-reduction process SORD;PTGS2 38408:[DB00480 DB00324] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 38409:[DB00480 DB01955] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01955|1,4-Butanediol MAN1B1;PLA2G2A;PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;PTGS2 GO:0006629| lipid metabolic process PLA2G2A;PLA2G2E;PTGS2 38410:[DB00480 DB07380] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07380|1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 38411:[DB00480 DB02067] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02067|Triglu-5-Formyl-Tetrahydrofolate SHMT1 common genes common pathways GO:1990830| SHMT1;TNFSF11 38412:[DB00480 DB03341] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03341|Coa-S-Acetyl 5-Bromotryptamine AANAT common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;AANAT GO:0034097| response to cytokine stimulus AANAT;PTGS2 38413:[DB00480 DB04938] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP3A4;CYP2B6;CYP2C9;CYP2D6 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP3A4;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;ESR1 38414:[DB00480 DB02477] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02477|[Cyclohexylethyl]-[[[[4-[2-Methyl-1-Imidazolyl-Butyl]Phenyl]Acetyl]-Seryl]-Lysinyl]-Amine NMT1 common genes common pathways 38415:[DB00480 DB05072] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05072|AV608 TACR1 common genes common pathways GO:0032355| response to estradiol stimulus TACR1;PTGS2 GO:0014070| response to organic cyclic compound TACR1;PTGS2 GO:0008217| regulation of blood pressure TACR1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0045907| positive regulation of vasoconstriction TACR1;PTGS2 GO:0006954| inflammatory response PTGS2;TACR1 GO:0019233| sensory perception of pain TACR1;PTGS2 38416:[DB00480 DB02648] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02648|(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium CRAT;CROT common genes common pathways GO:0006631| fatty acid metabolic process CRAT;PTGS2;CROT GO:0006629| lipid metabolic process CROT;PTGS2;CRAT 38417:[DB00480 DB02583] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02583|N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 38418:[DB00480 DB01727] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01727|Isocitric Acid icd;icd;ACO2;IDH2;IDH1 common genes common pathways GO:0006979| response to oxidative stress PTGS2;IDH1 GO:0055114| oxidation-reduction process PTGS2;IDH2;IDH1 GO:0014070| response to organic cyclic compound PTGS2;IDH1 38419:[DB00480 DB04629] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04629|Aplyronine A ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 38420:[DB00480 DB04230] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04230|Nitromethyldethia Coenzyme A CS common genes common pathways 38421:[DB00480 DB02078] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02078|Triglyme PFN2;cysE;FYN;PPIF common genes common pathways GO:0007275| multicellular organismal development TNFSF11;FYN GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FYN GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;PFN2 GO:0030154| cell differentiation TNFSF11;FYN GO:0051897| positive regulation of protein kinase B signaling cascade FYN;TNFSF11 GO:0042493| response to drug FYN;ABCB1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;PPIF GO:0007612| learning FYN;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;FYN GO:0006979| response to oxidative stress PPIF;PTGS2 38422:[DB00480 DB13961] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes PTGS2 common pathways GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound SREBF1;PTGS2;PPARG GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid PTGS2;SREBF1 GO:0034644| cellular response to UV PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PPARD;PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007613| memory PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0006954| inflammatory response NFKB1;PTGS2;NFKB2 GO:0010942| positive regulation of cell death PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;NFKB2;NFKB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:1990776| PTGS2 GO:0071260| cellular response to mechanical stimulus NFKB1;PTGS2 GO:0006629| lipid metabolic process PPARG;DGAT2;CYP3A4;PPARA;PPARD;SREBF1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PPARD;PPARG;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0055085| transmembrane transport ABCB1;CACNA1F;CACNA1S;CACNA1D;CACNA1C GO:0006979| response to oxidative stress PTGS2 GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0097756| PTGS2 GO:0030282| bone mineralization PTGS2 GO:0006810| transport ABCB1;CACNB4;CACNB1;CACNB3 GO:0046697| decidualization PTGS2;PPARD GO:0007568| aging SREBF1;NFKB2;PTGS2 GO:0050728| negative regulation of inflammatory response NFKB1;FFAR4;PPARD;PPARA;CDH5 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0042493| response to drug PPARG;ABCB1;SREBF1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TNFSF11;SREBF1;NFKB2;NFKB1 GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process NFKB1;PTGS2;PPARD;FFAR4 GO:0034097| response to cytokine stimulus PTGS2;NFKB2 GO:0032496| response to lipopolysaccharide NFKB2;PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0071284| cellular response to lead ion PTGS2 38423:[DB00480 DB01942] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGF1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMOX1 GO:0055114| oxidation-reduction process CTBP1;NOS1;GPHN;HMOX1;PTGS2 GO:2001225| regulation of chloride transport CA2;ABCB1 GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0007155| cell adhesion CDH5;CASK GO:0008284| positive regulation of cell proliferation PTGS2;FGF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CASK;NOS1;TNFSF11;FGF1 GO:0043406| positive regulation of MAP kinase activity FGF1;TNFSF11 GO:0010033| response to organic substance CA2;PTGS2 GO:0055085| transmembrane transport SLC16A3;ABCB1 GO:1902533| FGF1;TNFSF11 GO:0051260| protein homooligomerization HMOX1;TNFSF11 GO:0006979| response to oxidative stress PTGS2;HMOX1 GO:0071456| cellular response to hypoxia HMOX1;PTGS2 GO:0010469| regulation of receptor activity FGF1;TNFSF11 GO:0045780| positive regulation of bone resorption TNFSF11;CA2 GO:0034605| cellular response to heat FGF1;HMOX1;PTGS2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;TNFSF11 GO:0001525| angiogenesis PTGS2;HMOX1;FGF1 GO:0007275| multicellular organismal development TNFSF11;FGF1 GO:0008217| regulation of blood pressure HMOX1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;HMOX1;CTBP1;CDH5 GO:0030154| cell differentiation CTBP1;TNFSF11;FGF1 38424:[DB00480 DB08447] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08447|3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;PTGS2 GO:0006629| lipid metabolic process PLA2G2E;PTGS2 38425:[DB00480 DB08258] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08258|6-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEXANOIC ACID EPHX2 common genes common pathways GO:0008217| regulation of blood pressure EPHX2;PTGS2 GO:0006954| inflammatory response EPHX2;PTGS2 GO:0006629| lipid metabolic process EPHX2;PTGS2 38426:[DB00480 DB13508] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13508|Cloranolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;PTGS2 38427:[DB00480 DB03056] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03056|4-Piperidino-Piperidine CES1 common genes common pathways 38428:[DB00480 DB01007] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01007|Tioconazole CYP51A1;CYP19A1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2;CYP51A1 GO:0055114| oxidation-reduction process CYP2E1;CYP51A1;PTGS2;CYP2C8;CYP2C19;CYP19A1;CYP3A4 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 38429:[DB00480 DB06711] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06711|Naphazoline ADRA1A;ADRA2A common genes common pathways GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug ABCB1;ADRA1A;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA2A GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0007568| aging ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A 38430:[DB00480 DB00513] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00513|Aminocaproic Acid PLG;PLAT;LPA;AOX1 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;PLG GO:0006629| lipid metabolic process LPA;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AOX1 38431:[DB00480 DB03964] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03964|4-Hydroxy-Aconitate Ion ACO2 common genes common pathways 38432:[DB00480 DB07666] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07666|(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion DPP4;CDH5 38433:[DB00480 DB04237] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04237|Tris(Hydroxyethyl)Aminomethane AMY1A common genes common pathways 38434:[DB00480 DB03115] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03115|5-Bromo-N-(2,3-Dihydroxypropoxy)-3,4-Difluoro-2-[(2-Fluoro-4-Iodophenyl)Amino]Benzamide MAP2K1 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;CDH5;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAP2K1 38435:[DB00480 DB03924] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03924|5,8-Di-Amino-1,4-Dihydroxy-Anthraquinone CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 38436:[DB00480 DB02489] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 38437:[DB00480 DB13746] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13746|Bioallethrin CACNA1G;CACNA1H;CACNA1I;CACNA1A;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP2C8;CYP2C9;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9 GO:0006810| transport ABCB1;CACNA1I;CACNB4;CACNB3;CACNB1 GO:0055085| transmembrane transport CACNA1I;CACNA1A;CACNA1G;ABCB1;CACNA1F;CACNA1D;CACNA1C;CACNA1S;CACNA1H GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;PTGS2;CYP2C9;CYP3A4 38438:[DB00480 DB03061] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03061|(R)-N-(1-Methyl-Hexyl)-Formamide ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 38439:[DB00480 DB03802] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03802|1-[4-(Octahydro-Pyrido[1,2-a]Pyrazin-2-Yl)-Phenyl]-2-Phenyl-1,2,3,4-Tetrahydro-Isoquinolin-6-Ol ESR1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 38440:[DB00480 DB04365] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04365|Arecoline CHRM1;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 38441:[DB00480 DB01593] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0030154| cell differentiation TP53;KRT6A;NME1;TNFSF11 GO:0007613| memory APP;PTGS2 GO:0051384| response to glucocorticoid stimulus CPN1;PTGS2;APOA2 GO:0019722| calcium-mediated signaling APP;TNFSF11 GO:0007566| embryo implantation SOD1;PTGS2;MMP9 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation INS;PTGS2 GO:0034644| cellular response to UV TP73;TP53;PTGS2 GO:0070542| response to fatty acid PTGS2;PON1 GO:0032463| negative regulation of protein homooligomerization CLU;CRBN GO:0045907| positive regulation of vasoconstriction FGA;PTGS2 GO:0042633| hair cycle KRT14;PTGS2;KRT16 GO:0014070| response to organic cyclic compound MGMT;PTGS2;TP53 GO:0008285| negative regulation of cell proliferation APP;CDH5;HDAC4;NME1;PTGS2;TP73;HDAC1;TP53 GO:0008217| regulation of blood pressure SOD1;PTGS2;AGT;HBB GO:0001525| angiogenesis S100A7;PDCD6;PTGS2;FN1 GO:0007275| multicellular organismal development TNFSF11;F2;TP53;HRNR;TPI1 GO:0019233| sensory perception of pain BDKRB1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production C5;PTGS2;C3 GO:0001503| ossification MMP9;TNFSF11;AHSG GO:0006629| lipid metabolic process APOBR;APOE;APOL1;APOA1;C3;PON1;PTGS2;CLU GO:0071260| cellular response to mechanical stimulus HDAC4;AGT;PTGS2 GO:0043065| positive regulation of apoptotic process TP53;TP73;SOD1;PTGS2;MMP9;CLU;APP;KNG1 GO:0050727| regulation of inflammatory response AHSG;PTGS2;S100A9;S100A8;PGLYRP2;ESR1 GO:0042307| positive regulation of protein import into nucleus PTGS2;JUP GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;MT3;MDM2 GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A9;INS;APP;CLU;TNFSF11;S100A8;AGT GO:0070371| ERK1 and ERK2 cascade APOA1;MT3;TNFSF11;AGT GO:0006954| inflammatory response C5;C4B;BDKRB1;KNG1;SERPINA3;S100A8;KLKB1;HDAC4;S100A9;PTGS2;C3;KRT16 GO:0010942| positive regulation of cell death PTGS2;MT3;HBA1;HBB GO:0006955| immune response C8A;C1R;TNFSF11;IGLV3-21;IGKV1-17;VTN;C3;C1QC;IL3;JCHAIN;IGHA1;C8B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;JUP;HDAC4;ESR1;APP GO:0097756| PTGS2;INS GO:0071456| cellular response to hypoxia PTGS2;MT3;TP53;MDM2;P4HB GO:0007568| aging AGT;GSN;KRT16;PTGS2;TP53;KRT14;SOD1 GO:0006810| transport ABCB1;TTR GO:0032355| response to estradiol stimulus PTGS2;ESR1;AGT GO:0010469| regulation of receptor activity F2;DAND5;IL3;TNFSF11;AGT;TTR;INS GO:0098609| DSP;JUP;CDH5 GO:0034605| cellular response to heat PTGS2;TP53;PDCD6 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process TP53;CRBN GO:0051260| protein homooligomerization TNFSF11;APP;GLRA1;IDE GO:0098869| S100A9;PTGS2;APOE;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;INS;CLU;APP;AGT;HBB;PTGS2 GO:0006979| response to oxidative stress APP;APOE;TP53;SOD1;PRDX1;KRT1;MT3;PTGS2 GO:0055085| transmembrane transport APOA1;ABCB1 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5;APOA1 GO:0010033| response to organic substance PTGS2;SOD1 GO:0009887| organ morphogenesis APLP1;TNFSF11 GO:0046330| positive regulation of JNK cascade APP;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;AGT;JUP GO:0007612| learning APP;PTGS2 GO:0032496| response to lipopolysaccharide BDKRB1;S100A8;PTGS2;S100A7;HDAC1 GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0034097| response to cytokine stimulus PTGS2;ITIH4;TP53 GO:0007155| cell adhesion VTN;APP;APLP1;FN1;CDH5;IGFALS;JUP GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TP73;TP53;HDAC1;PARP1;ESR1;APP;TNFSF11;HDAC4 GO:0008284| positive regulation of cell proliferation HDAC4;AGT;FN1;MDM2;INS;HDAC1;KRT6A;F2;IL3;PTGS2 GO:0043066| negative regulation of apoptotic process HDAC1;TP53;SOD1;PTGS2;MT3;MMP9;MDM2;MGMT GO:0055114| oxidation-reduction process P4HB;GAPDHS;CP;CCS;ADH1C;PDIA3;SOD1;PRDX1;PTGS2 GO:0034332| adherens junction organization DSP;CDH5;JUP GO:0016567| protein ubiquitination CRBN;MDM2 GO:0042493| response to drug SOD1;TP73;HDAC1;TP53;NME1;PTGS2;APOA1;HDAC4;APOA2;MGMT;ABCB1;MDM2 GO:0006631| fatty acid metabolic process C3;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL3 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;APP;INS GO:0050728| negative regulation of inflammatory response APOA1;KRT1;APOE;CDH5 GO:0010243| response to organic nitrogen TP53;TP73;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HDAC4;PTGS2 GO:0019372| lipoxygenase pathway PON1;PTGS2 38442:[DB00480 DB09063] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation PTGS2;ALK GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2C9 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP3A4 GO:0051092| positive regulation of NF-kappaB transcription factor activity ALK;TNFSF11 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport ABCB1 38443:[DB00480 DB13893] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13893|Crotalus adamanteus antivenin PLA2G10;ENPP1;PLA2G10 common genes common pathways GO:0006955| immune response TNFSF11;ENPP1 GO:0006629| lipid metabolic process PTGS2;PLA2G10 GO:1990830| TNFSF11;PLA2G10 38444:[DB00480 DB04194] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04194|Chitotriose LYZ common genes common pathways GO:0006954| inflammatory response PTGS2;LYZ 38445:[DB00480 DB08387] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08387|2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 38446:[DB00480 DB00607] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;PTGS2 GO:0098869| PTGS2;ALB GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0055085| transmembrane transport SLC22A6;ABCB1 38447:[DB00480 DB05932] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0046330| positive regulation of JNK cascade TNFSF11;FLT4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VEGFA GO:0008284| positive regulation of cell proliferation FLT4;PTGS2;VEGFA;FLT1 GO:0043066| negative regulation of apoptotic process VEGFA;PTGS2;FLT4 GO:0060749| mammary gland alveolus development TNFSF11;VEGFA GO:0002548| monocyte chemotaxis FLT1;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;VEGFA GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0043406| positive regulation of MAP kinase activity VEGFA;FLT1;TNFSF11 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4 GO:0001525| angiogenesis PTGS2;FLT4;VEGFA;FLT1 GO:0007275| multicellular organismal development FLT1;VEGFA;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA GO:0030154| cell differentiation VEGFA;FLT1;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2 38448:[DB00480 DB06786] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0043066| negative regulation of apoptotic process SMO;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;SMO GO:0045944| positive regulation of transcription from RNA polymerase II promoter SMO;TNFSF11 GO:0042307| positive regulation of protein import into nucleus SMO;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0001503| ossification SMO;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;SMO 38449:[DB00480 DB00514] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0006954| inflammatory response RAC1;CYBA;PTGS2;CYBB GO:0006955| immune response NCF4;TNFSF11;OPRK1;OPRD1 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9;CYP2D6 GO:0071260| cellular response to mechanical stimulus RAC1;CYBA;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;RAC1 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:1990776| PTGS2;CYBB GO:0019233| sensory perception of pain CHRNA4;PTGS2;OPRD1;CHRNB2;OPRK1;OPRM1 GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0008217| regulation of blood pressure PTGS2;CYBA GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0045453| bone resorption RAC1;TNFSF11;RAC2 GO:0007613| memory PTGS2;CHRNA7;CHRNB2;SLC6A4 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0048661| positive regulation of smooth muscle cell proliferation CYBA;PTGS2 GO:0055114| oxidation-reduction process CYP3A5;CYP2E1;CYP3A7;CYP2C19;CYP2C8;CYBB;CYBA;PTGS2;CYP2D6;CYP2C9;CYP2B6;NCF2;NCF4;CYP3A4;NCF1 GO:0042493| response to drug SLC6A2;CYBB;PTGS2;CYBA;CYP2E1;ABCB1;SLC6A4 GO:0007155| cell adhesion CDH5;RAC1 GO:0008284| positive regulation of cell proliferation RAC2;PTGS2;CHRNA7 GO:0046330| positive regulation of JNK cascade NCF1;TNFSF11 GO:0007612| learning PTGS2;CHRNB2 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A2;ABCB1;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0071456| cellular response to hypoxia OPRD1;PTGS2;CYBB GO:0006810| transport ABCB1;SLC6A2 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 38450:[DB00480 DB07513] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07513|7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE MAOB common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOB GO:0042493| response to drug ABCB1;MAOB;PTGS2 GO:0032496| response to lipopolysaccharide MAOB;PTGS2 38451:[DB00480 DB13141] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP3A5;CYP3A4;CYP3A43 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38452:[DB00480 DB05096] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05096|LY2140023 GRM2;GRM3 common genes common pathways 38453:[DB00480 DB05343] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05343|Arundic acid S100B common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;TNFSF11 GO:0043065| positive regulation of apoptotic process S100B;PTGS2 GO:0007613| memory S100B;PTGS2 GO:0051384| response to glucocorticoid stimulus S100B;PTGS2 GO:0008284| positive regulation of cell proliferation S100B;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;S100B 38454:[DB00480 DB00134] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0042493| response to drug MTHFR;ABCB1;PTGS2 GO:0055114| oxidation-reduction process MTHFR;MSRA;MSRB1;MSRB2;MTRR;PTGS2 GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:1990830| TNFSF11;MAT2A GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:0006979| response to oxidative stress MSRB2;PTGS2;MSRA;MSRB1 GO:0051260| protein homooligomerization GLUL;TNFSF11 38455:[DB00480 DB04973] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04973|LErafAON RAF1 common genes common pathways GO:0043066| negative regulation of apoptotic process RAF1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;RAF1 GO:0030154| cell differentiation TNFSF11;RAF1 GO:0008285| negative regulation of cell proliferation PTGS2;RAF1;CDH5 GO:0007275| multicellular organismal development RAF1;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;RAF1 38456:[DB00480 DB05895] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05895|HGS-TR2J TNFRSF10B common genes common pathways GO:0032496| response to lipopolysaccharide TNFRSF10B;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;TNFRSF10B GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNFRSF10B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFRSF10B;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;TNFRSF10B GO:0071260| cellular response to mechanical stimulus TNFRSF10B;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;TNFRSF10B GO:0006954| inflammatory response TNFRSF10B;PTGS2 GO:0006955| immune response TNFRSF10B;TNFSF11 38457:[DB00480 DB02943] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways GO:0098869| GSTA1;PTGS2 38458:[DB00480 DB07280] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 38459:[DB00480 DB03182] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03182|Alpha-Fluoro-Carboxymethyldethia Coenzyme a Complex CS common genes common pathways 38460:[DB00480 DB02021] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02021|Fidarestat AKR1B1;AKR1B10 common genes common pathways GO:0055114| oxidation-reduction process AKR1B10;AKR1B1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0010033| response to organic substance PTGS2;AKR1B1 38461:[DB00480 DB02164] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02164|N-Sulfo-Flavin Mononucleotide HAO1 common genes common pathways GO:0006979| response to oxidative stress HAO1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;HAO1 38462:[DB00480 DB04616] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04616|TACRINE(8)-4-AMINOQUINOLINE ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 38463:[DB00480 DB03879] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03879|alpha-L-methyl-fucose MBL2 common genes common pathways GO:0006979| response to oxidative stress MBL2;PTGS2 38464:[DB00480 DB13923] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13923|Emicizumab F9;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 38465:[DB00480 DB01220] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01220|Rifaximin rpoB;NR1I2;CYP3A4;CYP2C19;CYP2C8;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP2C19;CYP3A4;CYP2D6 38466:[DB00480 DB05771] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05771|LLL-3348 IL10 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;IL10 GO:0043066| negative regulation of apoptotic process IL10;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL10 GO:0042493| response to drug ABCB1;PTGS2;IL10 GO:0050728| negative regulation of inflammatory response IL10;CDH5 GO:0007568| aging PTGS2;IL10 GO:0010033| response to organic substance IL10;PTGS2 GO:0006955| immune response TNFSF11;IL10 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL10;TNFSF11 GO:0006954| inflammatory response PTGS2;IL10 GO:0051384| response to glucocorticoid stimulus PTGS2;IL10 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;IL10 38467:[DB00480 DB07470] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07470|(3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 38468:[DB00480 DB06458] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06458|Remacemide CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38469:[DB00480 DB07333] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07333|N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE KDR common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process KDR;PTGS2 GO:0001525| angiogenesis KDR;PTGS2 GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0030154| cell differentiation TNFSF11;KDR 38470:[DB00480 DB07840] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways GO:0001525| angiogenesis FGFR1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;FGFR1 GO:0042127| regulation of cell proliferation PTGS2;FGFR1 GO:0008284| positive regulation of cell proliferation FGFR1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade FGFR1;TNFSF11 38471:[DB00480 DB05235] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05235|NRP409 CRYM;THRA;TTR;SERPINA7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;TNFSF11 GO:0055114| oxidation-reduction process CRYM;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport ABCB1;TTR GO:0009887| organ morphogenesis TNFSF11;THRA GO:0001503| ossification THRA;TNFSF11 38472:[DB00480 DB01295] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0042493| response to drug ABCB1;ADRA1A;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0007568| aging ADRA1A;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 38473:[DB00480 DB08164] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08164|(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 38474:[DB00480 DB01336] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways 38475:[DB00480 DB06655] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion CDH5;DPP4 GO:0019233| sensory perception of pain PTGS2;MME 38476:[DB00480 DB05268] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05268|iCo-007 RAF1 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RAF1;CDH5 GO:0030154| cell differentiation RAF1;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation RAF1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;RAF1 GO:0007275| multicellular organismal development TNFSF11;RAF1 GO:0043066| negative regulation of apoptotic process PTGS2;RAF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RAF1 38477:[DB00480 DB04539] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP19A1 GO:0098869| ALB;PTGS2 38478:[DB00480 DB04312] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04312|2,3-Difluorobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 38479:[DB00480 DB00559] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;EDNRB GO:0008217| regulation of blood pressure EDNRB;PTGS2;EDNRA GO:0014070| response to organic cyclic compound PTGS2;EDNRB GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 GO:0019233| sensory perception of pain PTGS2;EDNRB GO:0007568| aging EDNRB;PTGS2 GO:0006810| transport ABCB11;ABCB1 GO:0055085| transmembrane transport ABCB11;ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;EDNRB GO:0008284| positive regulation of cell proliferation EDNRB;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;EDNRB GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS2 38480:[DB00480 DB00162] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00162|Vitamin A RDH12;DHRS3;ALDH1A3;RETSAT;RDH11;DHRS4;RDH14;RDH8;LRAT;RBP1;RDH5;RDH13;RBP3;ALDH1A2;ALDH1A1;RLBP1;APOD;HPGDS;CYP1A1;CYP26A1;RBP5;RBP7;RBP4;RBP2;ALB common genes common pathways GO:1990830| LRAT;TNFSF11 GO:0010033| response to organic substance CYP1A1;PTGS2 GO:0098869| ALB;PTGS2 GO:0032355| response to estradiol stimulus ALDH1A2;PTGS2 GO:0007568| aging APOD;PTGS2;CYP1A1 GO:0042493| response to drug CYP1A1;PTGS2;APOD;ABCB1 GO:0006631| fatty acid metabolic process HPGDS;PTGS2 GO:0055114| oxidation-reduction process RDH14;DHRS3;RETSAT;RDH11;ALDH1A2;ALDH1A1;RDH13;RDH12;ALDH1A3;RDH8;CYP26A1;PTGS2;RDH5;CYP1A1;DHRS4 GO:0008284| positive regulation of cell proliferation PTGS2;ALDH1A2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0034097| response to cytokine stimulus PTGS2;ALDH1A2 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;ALDH1A2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS GO:0006633| fatty acid biosynthetic process HPGDS;PTGS2 GO:0019371| cyclooxygenase pathway HPGDS;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;ALDH1A2;ALDH1A3 GO:0006693| prostaglandin metabolic process PTGS2;HPGDS GO:0006629| lipid metabolic process HPGDS;APOD;PTGS2;RBP3 GO:0001525| angiogenesis PTGS2;APOD 38481:[DB00480 DB00823] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;ESR1;TNFSF11 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38482:[DB00480 DB05372] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05372|CP-945598 CNR1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CNR1 GO:0007568| aging CNR1;PTGS2 GO:0019233| sensory perception of pain PTGS2;CNR1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0043065| positive regulation of apoptotic process CNR1;PTGS2 GO:0007613| memory CNR1;PTGS2 38483:[DB00480 DB02643] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02643|N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate IGF1;MAOB common genes common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;IGF1 GO:0010469| regulation of receptor activity TNFSF11;IGF1 GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0043066| negative regulation of apoptotic process IGF1;PTGS2 GO:0008284| positive regulation of cell proliferation IGF1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IGF1;TNFSF11 GO:0055114| oxidation-reduction process MAOB;PTGS2 GO:0042493| response to drug MAOB;PTGS2;ABCB1 GO:0048661| positive regulation of smooth muscle cell proliferation IGF1;PTGS2 38484:[DB00480 DB07908] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07908|7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN PFN1 common genes common pathways 38485:[DB00480 DB06586] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06586|Cetilistat PNLIP common genes common pathways GO:0006629| lipid metabolic process PTGS2;PNLIP 38486:[DB00480 DB02684] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02684|5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine EPRS common genes common pathways 38487:[DB00480 DB00174] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC38A3;SLC16A10;ABCB1 GO:0043066| negative regulation of apoptotic process ASNS;PTGS2 38488:[DB00480 DB04873] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04873|Piboserod HTR4 common genes common pathways 38489:[DB00480 DB01154] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;KCNJ8 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2E1;PTGS2 GO:0042493| response to drug ABCB1;KCNJ11;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0006810| transport ABCB1;GABRA1 GO:0032355| response to estradiol stimulus PTGS2;KCNJ11 GO:0055085| transmembrane transport ABCB1;KCNJ11 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 38490:[DB00480 DB07046] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07046|2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide MAP2K1 common genes common pathways GO:0070371| ERK1 and ERK2 cascade MAP2K1;TNFSF11 GO:0008285| negative regulation of cell proliferation MAP2K1;CDH5;PTGS2 38491:[DB00480 DB02999] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02999|Quisqualate GRIA2;GRIK2 common genes common pathways GO:0006810| transport GRIK2;ABCB1 GO:0055085| transmembrane transport GRIK2;ABCB1 38492:[DB00480 DB02983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02983|Para-Mercury-Benzenesulfonic Acid CLC;ESR2 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;CLC GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2 38493:[DB00480 DB01031] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01031|Ethinamate CA1;CA2 common genes common pathways GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0045780| positive regulation of bone resorption CA2;TNFSF11 GO:0010033| response to organic substance CA2;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 38494:[DB00480 DB11937] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11937|Kynurenic Acid AHR;GPR35 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AHR 38495:[DB00480 DB06159] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06159|Rubitecan TOP1 common genes common pathways GO:0042493| response to drug TOP1;PTGS2;ABCB1 38496:[DB00480 DB05501] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0019722| calcium-mediated signaling CXCR4;CCR5;TNFSF11 GO:0006954| inflammatory response CCR5;PTGS2;CXCR4 GO:0006955| immune response CCR5;TNFSF11 38497:[DB00480 DB07771] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07771|[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID KRAS;FNTA;FNTB common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;KRAS GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;KRAS GO:0043406| positive regulation of MAP kinase activity KRAS;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CDH5 GO:0019221| cytokine-mediated signaling pathway KRAS;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;KRAS GO:0042127| regulation of cell proliferation PTGS2;FNTB 38498:[DB00480 DB03839] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03839|D-Tyrosine SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 38499:[DB00480 DB02400] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02400|5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione NQO1 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;NQO1 GO:0032355| response to estradiol stimulus PTGS2;NQO1 GO:0007568| aging NQO1;PTGS2 GO:0006979| response to oxidative stress PTGS2;NQO1 GO:0055114| oxidation-reduction process PTGS2;NQO1 GO:0043066| negative regulation of apoptotic process PTGS2;NQO1 38500:[DB00480 DB06862] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06862|2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID CASP3 common genes common pathways GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CASP3 GO:0042493| response to drug PTGS2;CASP3;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CASP3 GO:0010033| response to organic substance PTGS2;CASP3 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2 GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0014070| response to organic cyclic compound CASP3;PTGS2 38501:[DB00480 DB06492] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06492|Mirococept C3 common genes common pathways GO:0006631| fatty acid metabolic process PTGS2;C3 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;C3 GO:0006629| lipid metabolic process C3;PTGS2 GO:0006954| inflammatory response C3;PTGS2 GO:0006955| immune response C3;TNFSF11 38502:[DB00480 DB01426] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A GO:0006954| inflammatory response PTGS2;ORM1 38503:[DB00480 DB04551] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04551|beta-D-fructofuranose 1,6-bisphosphate glpK;PKLR;SLCO2A1 common genes common pathways GO:0010226| response to lithium ion PTGS2;PKLR GO:0055085| transmembrane transport ABCB1;SLCO2A1 38504:[DB00480 DB12520] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12520|Plozalizumab CCR2 common genes common pathways GO:0050870| positive regulation of T cell activation TNFSF11;CCR2 GO:0019233| sensory perception of pain PTGS2;CCR2 GO:0006955| immune response TNFSF11;CCR2 GO:0006954| inflammatory response CCR2;PTGS2 GO:0019221| cytokine-mediated signaling pathway CCR2;TNFSF11 GO:0002548| monocyte chemotaxis TNFSF11;CCR2 38505:[DB00480 DB07558] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07558|acetylleucyl-leucyl-norleucinal PSMA7 common genes common pathways GO:0055085| transmembrane transport ABCB1;PSMA7 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;PSMA7 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;PSMA7 38506:[DB00480 DB08830] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08830|Dehydroascorbic Acid SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLC2A1;ABCB1 GO:0071260| cellular response to mechanical stimulus SLC2A1;PTGS2 GO:0042908| xenobiotic transport SLC2A1;ABCB1 38507:[DB00480 DB07958] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07958|(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID PLA2G2E common genes common pathways GO:0006954| inflammatory response PTGS2;PLA2G2E GO:0006629| lipid metabolic process PLA2G2E;PTGS2 38508:[DB00480 DB00462] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 38509:[DB00480 DB04850] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1 GO:0055114| oxidation-reduction process MAOA;PTGS2 38510:[DB00480 DB05142] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05142|ND7001 PDE2A;PDE2A common genes common pathways GO:0071260| cellular response to mechanical stimulus PDE2A;PTGS2 38511:[DB00480 DB08949] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08949|Inositol nicotinate HCAR3;HCAR2;ATP5B;DGAT2;SLC5A8 common genes common pathways GO:0055085| transmembrane transport SLC5A8;ABCB1 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway SLC5A8;PTGS2 GO:0001525| angiogenesis ATP5B;PTGS2 GO:0006629| lipid metabolic process PTGS2;ATP5B;DGAT2 38512:[DB00480 DB06266] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CFTR 38513:[DB00480 DB04724] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04724|(S)-2-((S)-3-ISOBUTYL-2,5-DIOXO-4-QUINOLIN-3-YLMETHYL-[1,4]DIAZEPAN-1YL)-N-METHYL-3-NAPHTALEN-2-YL-PROPIONAMIDE ITGAL common genes common pathways GO:0007155| cell adhesion ITGAL;CDH5 GO:0098609| ITGAL;CDH5 GO:0006954| inflammatory response ITGAL;PTGS2 38514:[DB00480 DB04858] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 38515:[DB00480 DB03348] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03348|Huperzine B ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 38516:[DB00480 DB05930] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05930|SB-559448 MPL common genes common pathways GO:0019221| cytokine-mediated signaling pathway MPL;TNFSF11 38517:[DB00480 DB01864] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01864|5'-Guanosine-Diphosphate-Monothiophosphate ARF6;TGM3;ftsZ;RAB11A common genes common pathways GO:0030154| cell differentiation ARF6;TNFSF11 GO:0007155| cell adhesion ARF6;CDH5 38518:[DB00480 DB07528] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07528|3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one KDR common genes common pathways GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0001525| angiogenesis KDR;PTGS2 GO:0030154| cell differentiation TNFSF11;KDR GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0008284| positive regulation of cell proliferation PTGS2;KDR 38519:[DB00480 DB02071] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02071|WAY-151693 MMP13 common genes common pathways GO:0030282| bone mineralization MMP13;PTGS2 38520:[DB00480 DB05457] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05457|OSI-7904L TYMS common genes common pathways GO:0034097| response to cytokine stimulus TYMS;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;TYMS GO:0007568| aging TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;TYMS 38521:[DB00480 DB02032] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways GO:0008217| regulation of blood pressure PTGS2;ACE 38522:[DB00480 DB00668] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process TNF;PTGS2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS2 GO:0007275| multicellular organismal development TNF;ADRA1B;TNFSF11;ADRA1D GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0006955| immune response TNFSF11;TNF GO:0006954| inflammatory response TNF;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0045907| positive regulation of vasoconstriction ADRA1D;PTGS2;ADRA1B;ADRA1A GO:0045453| bone resorption TNFSF11;ADRB2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1A;ADRA1D GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0014070| response to organic cyclic compound PTGS2;COMT GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA1D;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11;TNF GO:0032496| response to lipopolysaccharide MAOB;PTGS2;COMT GO:0007612| learning COMT;PTGS2 GO:0042127| regulation of cell proliferation TNF;PTGS2 GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug PTGS2;ADRA1A;MAOB;ABCB1;COMT GO:0055114| oxidation-reduction process MAOB;PTGS2;MAOA;CYP2C9;CYP3A4 GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0010469| regulation of receptor activity TNF;TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0007568| aging PTGS2;ADRA1A GO:0009887| organ morphogenesis TNFSF11;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;TNF GO:0055085| transmembrane transport ABCB1;SLC22A1;SLC22A2 38523:[DB00480 DB04489] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04489|Guanidinoethylmercaptosuccinic acid CPD common genes common pathways 38524:[DB00480 DB11081] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11081|Aluminum chloride GLUD1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GLUD1 38525:[DB00480 DB06011] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06011|AMG-222 DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 38526:[DB00480 DB05395] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05395|Amibegron ADRB3 common genes common pathways GO:0050873| brown fat cell differentiation ADRB3;PTGS2 GO:0007568| aging ADRB3;PTGS2 38527:[DB00480 DB08098] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08098|{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0010033| response to organic substance AKR1B1;PTGS2 38528:[DB00480 DB00699] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00699|Nicergoline ADRA1A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0007568| aging ADRA1A;PTGS2 38529:[DB00480 DB01433] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01433|Methadyl acetate OPRM1 common genes common pathways GO:0009314| response to radiation OPRM1;PTGS2 GO:0019233| sensory perception of pain PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 38530:[DB00480 DB01171] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01171|Moclobemide MAOA;MAOA;MAOB;MAOB;MAOA;MAOB;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP2D6 GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0042493| response to drug PTGS2;MAOB;ABCB1 GO:0055114| oxidation-reduction process MAOA;PTGS2;CYP2C19;MAOB;CYP2C9;CYP2D6 38531:[DB00480 DB05678] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05678|SLx-4090 MTTP common genes common pathways GO:0006629| lipid metabolic process MTTP;PTGS2 38532:[DB00480 DB00532] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00532|Mephenytoin SCN5A;NR1I2;CYP2C19;CYP2B6;CYP1A2;CYP2D6;CYP2C8;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2D6;CYP2C9 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP2C19;CYP1A2;CYP2B6;CYP2C9;CYP2D6 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2 GO:0055085| transmembrane transport SCN5A;ABCB1 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 38533:[DB00480 DB06755] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06755|Beta carotene BCO1;VLDLR;RBP1;RBP2;RBP3;RBP4;RBP5 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;BCO1 GO:0006629| lipid metabolic process VLDLR;RBP3;PTGS2 GO:0007613| memory VLDLR;PTGS2 38534:[DB00480 DB01017] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0001503| ossification MMP9;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B;CASP1 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2;MMP9 GO:0050727| regulation of inflammatory response PTGS2;CASP1 GO:0042327| positive regulation of phosphorylation TNFSF11;VEGFA GO:0031622| positive regulation of fever generation PTGS2;IL1B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;IL1B;TNFSF11 GO:0001525| angiogenesis PTGS2;VEGFA GO:0007275| multicellular organismal development TNFSF11;VEGFA GO:0010575| positive regulation vascular endothelial growth factor production IL1B;PTGS2 GO:0006954| inflammatory response ALOX5;PTGS2;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity IL1B;TNFSF11 GO:0006955| immune response IL1B;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;TNFSF11 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2 GO:0030154| cell differentiation VEGFA;TNFSF11 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0007566| embryo implantation IL1B;MMP9;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;IL1B;CDH5 GO:0014070| response to organic cyclic compound CASP3;PTGS2 GO:0060749| mammary gland alveolus development VEGFA;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL1B;VEGFA GO:0008284| positive regulation of cell proliferation PTGS2;VEGFA;IL1B GO:0043066| negative regulation of apoptotic process PTGS2;VEGFA;CASP3;MMP9 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;IL1B GO:0032496| response to lipopolysaccharide CASP1;IL1B;CASP3;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL1B GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0055114| oxidation-reduction process CYCS;PTGS2;ALOX5 GO:0042493| response to drug CASP3;PTGS2;ABCB1 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process IL1B;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0010469| regulation of receptor activity IL1B;TNFSF11;VEGFA GO:0032355| response to estradiol stimulus PTGS2;CASP3 GO:0043406| positive regulation of MAP kinase activity VEGFA;TNFSF11 GO:0010033| response to organic substance CASP3;PTGS2 GO:0055085| transmembrane transport SLC22A11;SLC22A7;SLC22A8;SLC22A6;ABCB1 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 38535:[DB00480 DB02871] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02871|3-Butylthiolane 1-Oxide ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 38536:[DB00480 DB07397] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07397|(5S)-5-(2-amino-2-oxoethyl)-4-oxo-N-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)methyl]-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidine-2-carboxamide MMP8 common genes common pathways 38537:[DB00480 DB03283] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03283|beta-L-fucose ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 38538:[DB00480 DB03712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03712|RU85053 SRC common genes common pathways GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| CDH5;SRC GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0070542| response to fatty acid SRC;PTGS2 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption TNFSF11;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC 38539:[DB00480 DB01728] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01728|3-[Aminoethylphosphoryl]-[1,2-Di-Palmitoyl]-Sn-Glycerol RHO common genes common pathways 38540:[DB00480 DB02391] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02391|2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One PNP common genes common pathways GO:0042493| response to drug PNP;ABCB1;PTGS2 GO:0006955| immune response TNFSF11;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP 38541:[DB00480 DB02020] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02020|Alrestatin AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0010033| response to organic substance AKR1B1;PTGS2 38542:[DB00480 DB02497] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02497|L-Alpha-Glycerophosphorylserine ANXA5 common genes common pathways GO:0010033| response to organic substance PTGS2;ANXA5 GO:0043066| negative regulation of apoptotic process PTGS2;ANXA5 38543:[DB00480 DB05478] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38544:[DB00480 DB01178] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01178|Chlormezanone TSPO common genes common pathways GO:0007568| aging PTGS2;TSPO GO:0010042| response to manganese ion PTGS2;TSPO GO:0042493| response to drug TSPO;ABCB1;PTGS2 GO:0043065| positive regulation of apoptotic process TSPO;PTGS2 38545:[DB00480 DB03214] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;IL4I1 38546:[DB00480 DB06987] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06987|(R)-Atenolol LTF;PLA2G2E common genes common pathways GO:0043066| negative regulation of apoptotic process LTF;PTGS2 GO:0001503| ossification TNFSF11;LTF GO:0006629| lipid metabolic process PTGS2;PLA2G2E GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;LTF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;LTF GO:0006954| inflammatory response PLA2G2E;PTGS2 38547:[DB00480 DB11623] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11623|Candoxatrilat MME common genes common pathways GO:0019233| sensory perception of pain MME;PTGS2 38548:[DB00480 DB02299] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02299|Arginineamide KCNA4 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;KCNA4 GO:0055085| transmembrane transport ABCB1;KCNA4 38549:[DB00480 DB11582] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes TNFSF11 common pathways GO:0030154| cell differentiation TNFSF11 GO:0071847| TNFSF11-mediated signaling pathway TNFSF11 GO:0071812| positive regulation of fever generation by positive regulation of prostaglandin secretion TNFSF11 GO:0019722| calcium-mediated signaling TNFSF11 GO:0071848| positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling TNFSF11 GO:0050870| positive regulation of T cell activation TNFSF11 GO:0045453| bone resorption TNFSF11 GO:0007257| activation of JUN kinase activity TNFSF11 GO:0051466| positive regulation of corticotropin-releasing hormone secretion TNFSF11 GO:0002158| osteoclast proliferation TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11 GO:0007275| multicellular organismal development TNFSF11 GO:0001503| ossification TNFSF11 GO:0038001| paracrine signaling TNFSF11 GO:0045672| positive regulation of osteoclast differentiation TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11 GO:0033598| mammary gland epithelial cell proliferation TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11 GO:0055074| calcium ion homeostasis TNFSF11 GO:0006955| immune response TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11 GO:0006810| transport GABRB1;GABRA6;GABRA4;GABRD;GABRA5;GABRA3;GABRB2;GABRG2;ABCB1;GABRA1;GABRB3 GO:0010469| regulation of receptor activity TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11 GO:0045780| positive regulation of bone resorption TNFSF11 GO:0045670| regulation of osteoclast differentiation TNFSF11 GO:2001206| positive regulation of osteoclast development TNFSF11 GO:1902533| TNFSF11 GO:0051260| protein homooligomerization GLRA1;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11 GO:1990830| TNFSF11 GO:0009887| organ morphogenesis TNFSF11 GO:0046330| positive regulation of JNK cascade TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11 GO:0002548| monocyte chemotaxis TNFSF11 GO:0030316| osteoclast differentiation TNFSF11 GO:0042493| response to drug ABCB1;GABRG3;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11 GO:0034112| positive regulation of homotypic cell-cell adhesion TNFSF11 38550:[DB00480 DB03062] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03062|(1-Methyl-1h-Imidazol-2-Yl)-(3-Methyl-4-{3-[(Pyridin-3-Ylmethyl)-Amino]-Propoxy}-Benzofuran-2-Yl)-Methanone NMT1;NMT1 common genes common pathways 38551:[DB00480 DB08799] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08799|Antazoline HRH1 common genes common pathways GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 38552:[DB00480 DB03934] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03934|Protoporphyrin Ix Containing Zn CYCS common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYCS 38553:[DB00480 DB06081] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06081|Caplacizumab VWF common genes common pathways GO:0051260| protein homooligomerization VWF;TNFSF11 GO:0007155| cell adhesion CDH5;VWF 38554:[DB00480 DB12637] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 38555:[DB00480 DB07000] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07000|N-{2,4-difluoro-3-[(5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]phenyl}ethanesulfonamide BRAF common genes common pathways GO:0009887| organ morphogenesis TNFSF11;BRAF GO:0042127| regulation of cell proliferation BRAF;PTGS2 GO:0043066| negative regulation of apoptotic process BRAF;PTGS2 GO:0030154| cell differentiation BRAF;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BRAF 38556:[DB00480 DB07070] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07070|(2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid PPARD common genes common pathways GO:0007566| embryo implantation PPARD;PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0006629| lipid metabolic process PPARD;PTGS2 GO:0010033| response to organic substance PPARD;PTGS2 GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0046697| decidualization PTGS2;PPARD GO:0050728| negative regulation of inflammatory response PPARD;CDH5 GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0043066| negative regulation of apoptotic process PPARD;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PPARD 38557:[DB00480 DB05447] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05447|AVI-4557 HNF4A common genes common pathways GO:0008285| negative regulation of cell proliferation HNF4A;PTGS2;CDH5 GO:0006629| lipid metabolic process PTGS2;HNF4A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HNF4A 38558:[DB00480 DB07485] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07485|4,4'-cyclohexane-1,1-diyldiphenol ESRRG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;TNFSF11 38559:[DB00480 DB01190] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38560:[DB00480 DB05107] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05107|16-Bromoepiandrosterone G6PD common genes common pathways GO:0055114| oxidation-reduction process PTGS2;G6PD GO:0006629| lipid metabolic process PTGS2;G6PD GO:0014070| response to organic cyclic compound PTGS2;G6PD 38561:[DB00480 DB01990] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01990|Cholesterol sulfate RORA common genes common pathways GO:0001525| angiogenesis PTGS2;RORA GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;RORA GO:0071456| cellular response to hypoxia PTGS2;RORA GO:0045944| positive regulation of transcription from RNA polymerase II promoter RORA;TNFSF11 GO:0050728| negative regulation of inflammatory response CDH5;RORA 38562:[DB00480 DB03682] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03682|Dibenzofuran-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TTR;TNFSF11 38563:[DB00480 DB02868] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02868|3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine CALM1 common genes common pathways GO:0055085| transmembrane transport CALM1;ABCB1 38564:[DB00480 DB00202] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0007613| memory CHRNA7;PTGS2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;CHRM1 GO:0007612| learning PTGS2;BCHE GO:0042127| regulation of cell proliferation PTGS2;CHRNA10 GO:0042493| response to drug ABCB1;BCHE;PTGS2 38565:[DB00480 DB03591] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03591|RU82209 SRC common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| CDH5;SRC GO:1902533| TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC 38566:[DB00480 DB05243] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05243|XL019 JAK2 common genes common pathways GO:0019221| cytokine-mediated signaling pathway TNFSF11;JAK2 GO:0008284| positive regulation of cell proliferation PTGS2;JAK2 GO:0042127| regulation of cell proliferation JAK2;PTGS2 GO:0032496| response to lipopolysaccharide JAK2;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;JAK2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;JAK2 GO:0006979| response to oxidative stress PTGS2;JAK2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;JAK2 GO:0043065| positive regulation of apoptotic process PTGS2;JAK2 GO:0050727| regulation of inflammatory response JAK2;PTGS2 GO:0008285| negative regulation of cell proliferation JAK2;PTGS2;CDH5 GO:0030154| cell differentiation JAK2;TNFSF11 38567:[DB00480 DB11692] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11692|Pavinetant TACR3 common genes common pathways GO:0007568| aging PTGS2;TACR3 GO:0032355| response to estradiol stimulus TACR3;PTGS2 38568:[DB00480 DB07157] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07157|(5R,6S,8S)-8-[3-(AMINOMETHYL)PHENYL]-6-HYDROXY-5-ISOPROPYL-3-OXO-1-PHENYL-2,7-DIOXA-4-AZA-6-PHOSPHANONAN-9-OIC ACID 6-OXIDE CPB1 common genes common pathways 38569:[DB00480 DB01404] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01404|Ginseng IL6;PTGS2;AHR common genes PTGS2 common pathways GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0010469| regulation of receptor activity TNFSF11;IL6 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation IL6;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL6 GO:0009750| response to fructose stimulus PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0002548| monocyte chemotaxis TNFSF11;IL6 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS2 GO:0008284| positive regulation of cell proliferation IL6;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;TNFSF11;AHR GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process IL6;PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;IL6;CDH5 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;IL6 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;IL6 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response IL6;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity IL6;TNFSF11 GO:0006955| immune response IL6;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;IL6 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;IL6 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain PTGS2 38570:[DB00480 DB08006] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08006|N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine DHODH common genes common pathways GO:0042493| response to drug PTGS2;DHODH;ABCB1 GO:0055114| oxidation-reduction process PTGS2;DHODH GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0014070| response to organic cyclic compound DHODH;PTGS2 38571:[DB00480 DB06735] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06735|Enclomiphene CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006629| lipid metabolic process PTGS2;CYP2D6 38572:[DB00480 DB01364] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;BCHE;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0042493| response to drug ABCB1;BCHE;SLC6A2;PTGS2;ADRA1A GO:0007155| cell adhesion ACHE;CDH5 GO:0007612| learning PTGS2;BCHE GO:0055085| transmembrane transport SLC18A2;SLC6A2;ABCB1 GO:0007568| aging PTGS2;ADRA1A GO:0006810| transport ABCB1;SLC6A2 38573:[DB00480 DB06697] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2B6;CYP2D6;PTGS2;CYP2C19;CYP3A5 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4;PTGS2 38574:[DB00480 DB03769] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03769|D-Eritadenine AHCY common genes common pathways 38575:[DB00480 DB04682] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04682|Octylphenoxy polyethoxyethanol TNNC2 common genes common pathways 38576:[DB00480 DB07787] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07787|5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE PARP1 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 38577:[DB00480 DB02426] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02426|Carboxyatractyloside SLC25A4 common genes common pathways GO:0006810| transport ABCB1;SLC25A4 GO:0055085| transmembrane transport ABCB1;SLC25A4 38578:[DB00480 DB06997] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06997|2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET 38579:[DB00480 DB07966] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07966|[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile SRC common genes common pathways GO:0070542| response to fatty acid SRC;PTGS2 GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug ABCB1;SRC;PTGS2 38580:[DB00480 DB05464] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05464|NOX-700 NFKB2;NFKB1 common genes common pathways GO:0032496| response to lipopolysaccharide NFKB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NFKB2;NFKB1 GO:0043066| negative regulation of apoptotic process NFKB1;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;NFKB2 GO:0050728| negative regulation of inflammatory response NFKB1;CDH5 GO:0007568| aging PTGS2;NFKB2 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;NFKB1;NFKB2 GO:0006954| inflammatory response NFKB1;NFKB2;PTGS2 38581:[DB00480 DB04381] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04381|Crotonaldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ALDH2 38582:[DB00480 DB01644] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01644|3,6-Dihydroxy-Xanthene-9-Propionic Acid GSR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GSR GO:0098869| PTGS2;GSR 38583:[DB00480 DB03991] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;NEU2 38584:[DB00480 DB08350] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08350|5-[3-(2-METHOXYPHENYL)-1H-PYRROLO[2,3-B]PYRIDIN-5-YL]-N,N-DIMETHYLPYRIDINE-3-CARBOXAMIDE ABL1 common genes common pathways GO:0042127| regulation of cell proliferation ABL1;PTGS2 GO:0007155| cell adhesion CDH5;ABL1 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;PTGS2 38585:[DB00480 DB08743] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08743|2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 38586:[DB00480 DB05200] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05200|AT2220 GAA common genes common pathways 38587:[DB00480 DB01472] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01472|4-Methoxyamphetamine SLC6A3;SLC6A4;SLC18A2;ADRA1A;ADRA2A;MAOA;MAOB;CYP2D6 common genes common pathways GO:0007568| aging SLC6A3;ADRA1A;PTGS2 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;SLC18A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA2A GO:0055114| oxidation-reduction process MAOA;PTGS2;MAOB;CYP2D6 GO:0042493| response to drug PTGS2;ADRA1A;SLC6A3;MAOB;ABCB1;SLC6A4 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0007613| memory PTGS2;SLC6A4 GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 38588:[DB00480 DB14707] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14707|Cemiplimab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PDCD1 GO:0007275| multicellular organismal development PDCD1;TNFSF11 GO:0043065| positive regulation of apoptotic process PDCD1;PTGS2 38589:[DB00480 DB12960] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12960|INCB-9471 CCR5 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;CCR5 GO:0006955| immune response CCR5;TNFSF11 GO:0006954| inflammatory response CCR5;PTGS2 38590:[DB00480 DB09333] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09333|Iopodic acid DIO3;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process PTGS2;DIO3 GO:0098869| ALB;PTGS2 38591:[DB00480 DB11571] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11571|Human Thrombin F5;F8;F11;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0055114| oxidation-reduction process PTGS2;F8 GO:0045907| positive regulation of vasoconstriction FGG;PTGS2;FGA;FGB 38592:[DB00480 DB06707] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA2C GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 38593:[DB00480 DB09143] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09143|Sonidegib SMO;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter SMO;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;SMO GO:0043066| negative regulation of apoptotic process SMO;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0007275| multicellular organismal development TNFSF11;SMO GO:0001503| ossification SMO;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0042307| positive regulation of protein import into nucleus PTGS2;SMO 38594:[DB00480 DB07602] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07602|S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE EGFR common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0014070| response to organic cyclic compound PTGS2;EGFR GO:0007275| multicellular organismal development TNFSF11;EGFR GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification TNFSF11;EGFR GO:0098609| CDH5;EGFR GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0006979| response to oxidative stress EGFR;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity EGFR;TNFSF11 GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0043066| negative regulation of apoptotic process EGFR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;TNFSF11 38595:[DB00480 DB08818] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08818|Hyaluronic acid CD44;ICAM1;HMMR;NCAN;VCAN;C1QBP;HAPLN1;HAPLN3;HAPLN4;HABP2;LAYN;STAB2;TNFAIP6;IMPG2;HABP4 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;CD44 GO:0007155| cell adhesion CD44;STAB2;ICAM1;NCAN;HAPLN4;HABP2;CDH5;HAPLN1;HAPLN3;TNFAIP6;VCAN GO:0032496| response to lipopolysaccharide ICAM1;PTGS2 GO:0050728| negative regulation of inflammatory response TNFAIP6;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade C1QBP;TNFSF11 GO:0042493| response to drug ICAM1;ABCB1;PTGS2 GO:0051926| negative regulation of calcium ion transport ICAM1;PTGS2 GO:0055114| oxidation-reduction process STAB2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ICAM1 GO:0098609| CD44;ICAM1;CDH5 GO:0071456| cellular response to hypoxia ICAM1;PTGS2 GO:1990830| TNFSF11;ICAM1 GO:0043065| positive regulation of apoptotic process PTGS2;C1QBP GO:0030728| ovulation PTGS2;TNFAIP6 GO:0071260| cellular response to mechanical stimulus HABP4;PTGS2 GO:0001525| angiogenesis PTGS2;STAB2 GO:0007275| multicellular organismal development VCAN;TNFSF11 GO:0006954| inflammatory response TNFAIP6;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity ICAM1;TNFSF11 GO:0006955| immune response TNFSF11;C1QBP GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CD44 GO:0045907| positive regulation of vasoconstriction ICAM1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;CD44 GO:0014070| response to organic cyclic compound PTGS2;ICAM1 38596:[DB00480 DB07609] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07609|N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;PTGS2 38597:[DB00480 DB00835] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006954| inflammatory response PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;CYP2C19;CYP2C8;PTGS2;CYP2B6;CYP3A4 38598:[DB00480 DB03323] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03323|Maltose AMY2B;aglA common genes common pathways 38599:[DB00480 DB04617] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04617|(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 38600:[DB00480 DB00576] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0098869| ALB;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 38601:[DB00480 DB08021] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08021|5-bromo-N-(3-chloro-2-(4-(prop-2-ynyl)piperazin-1-yl)phenyl)furan-2-carboxamide MAPK10 common genes common pathways 38602:[DB00480 DB04463] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04463|3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol CBR1;CBR1 common genes common pathways GO:0019371| cyclooxygenase pathway CBR1;PTGS2 GO:0055114| oxidation-reduction process CBR1;PTGS2 38603:[DB00480 DB00368] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter POU5F1;TNFSF11;ADRB2 GO:0008284| positive regulation of cell proliferation PTGS2;ADRA2A;ADRA1D GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug ADRA1A;PTGS2;SLC6A2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;PAH GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging ADRB3;ADRA1A;PTGS2 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0055085| transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2;SLC22A5;SLC6A2;SLC18A1;SLC18A2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0007275| multicellular organismal development ADRA1B;TNFSF11;POU5F1;ADRA1D GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB3;ADRB2 GO:0045907| positive regulation of vasoconstriction ADRA2C;ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0006855| drug transmembrane transport ABCB1;SLC22A1;SLC22A3;SLC18A1;SLC22A5;SLC22A2 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;PTGS2;ADRA1B;ADRA1A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 38604:[DB00480 DB04759] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04759|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-(3-METHYL-BENZYLAMIDE) MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13 38605:[DB00480 DB08238] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08238|5-AMINO-NAPHTALENE-2-MONOSULFONATE FGF1 common genes common pathways GO:0043406| positive regulation of MAP kinase activity FGF1;TNFSF11 GO:0034605| cellular response to heat PTGS2;FGF1 GO:0010469| regulation of receptor activity TNFSF11;FGF1 GO:1902533| TNFSF11;FGF1 GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;TNFSF11 GO:0008284| positive regulation of cell proliferation FGF1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;TNFSF11 GO:0030154| cell differentiation FGF1;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;FGF1 GO:0001525| angiogenesis PTGS2;FGF1 38606:[DB00480 DB03535] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03535|Z-Pro-Prolinal PREP common genes common pathways 38607:[DB00480 DB00151] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways GO:0006979| response to oxidative stress GSS;GCLC;PTGS2;GCLM GO:0007568| aging GSS;GCLC;PTGS2;GCLM GO:1990830| GCLM;CTH;TNFSF11 GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:0034612| response to tumor necrosis factor PTGS2;GSS GO:0043066| negative regulation of apoptotic process GCLC;CTH;MGMT;PTGS2 GO:0010243| response to organic nitrogen CDO1;PTGS2 GO:0055114| oxidation-reduction process CBS;CDO1;PTGS2 GO:0042493| response to drug PTGS2;GCLM;ABCB1;MGMT GO:0051384| response to glucocorticoid stimulus CDO1;PTGS2;GOT1 GO:0014070| response to organic cyclic compound MGMT;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;GCLC GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CTH GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CTH GO:0006954| inflammatory response CDO1;PTGS2 38608:[DB00480 DB02751] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02751|Glycocyamine GAMT common genes common pathways GO:0009887| organ morphogenesis GAMT;TNFSF11 38609:[DB00480 DB03185] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways 38610:[DB00480 DB03453] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03453|(R)—N[2-[1-(aminoiminomethyl)-3-piperidinyl]-1-oxoethyl]-4-(phenylethynyl)-l-phenylalanine methylester IL2 common genes common pathways GO:0006955| immune response TNFSF11;IL2 GO:0050728| negative regulation of inflammatory response CDH5;IL2 GO:0043066| negative regulation of apoptotic process IL2;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;TNFSF11 GO:0007155| cell adhesion IL2;CDH5 GO:0010469| regulation of receptor activity IL2;TNFSF11 38611:[DB00480 DB08024] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08024|1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion CDH5;DPP4 38612:[DB00480 DB07586] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07586|5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE HDAC8 common genes common pathways 38613:[DB00480 DB03516] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03516|Eniluracil DPYD;AOX1;XDH common genes common pathways GO:0055114| oxidation-reduction process XDH;PTGS2;AOX1;DPYD 38614:[DB00480 DB07330] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07330|trans-4-(7-carbamoyl-1H-benzimidazol-2-yl)-1-propylpiperidinium PARP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 38615:[DB00480 DB03128] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2;CHRM1 GO:0055085| transmembrane transport ABCB1;SLC22A1;SLC22A5 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A5 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0007613| memory PTGS2;CHRNA7 38616:[DB00480 DB08888] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08888|Ocriplasmin FN1;A2M;SERPINF2 common genes common pathways GO:0001525| angiogenesis PTGS2;FN1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;SERPINF2 GO:0071636| positive regulation of transforming growth factor beta production SERPINF2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter SERPINF2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;FN1 GO:0007155| cell adhesion FN1;CDH5 GO:0046330| positive regulation of JNK cascade TNFSF11;SERPINF2 GO:0010033| response to organic substance PTGS2;SERPINF2 38617:[DB00480 DB03824] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03824|7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline PNMT common genes common pathways 38618:[DB00480 DB01306] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01306|Insulin Aspart INSR common genes common pathways GO:0007613| memory INSR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;INSR GO:0007612| learning PTGS2;INSR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR GO:0009887| organ morphogenesis INSR;TNFSF11 38619:[DB00480 DB14570] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38620:[DB00480 DB02198] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02198|2-Bromoacetyl Group PTGS1 common genes common pathways GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 38621:[DB00480 DB00148] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0009887| organ morphogenesis GAMT;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC22A5;SLC6A8 GO:0006810| transport SLC6A8;ABCB1 38622:[DB00480 DB07780] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07780|Farnesyl diphosphate FNTA;FNTB;KRAS;FDPS;ispU;GGPS1;RABGGTA;RABGGTB common genes common pathways GO:0043406| positive regulation of MAP kinase activity KRAS;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FNTA GO:0008284| positive regulation of cell proliferation PTGS2;KRAS GO:0042127| regulation of cell proliferation FNTB;PTGS2 GO:0019221| cytokine-mediated signaling pathway KRAS;TNFSF11 GO:0051384| response to glucocorticoid stimulus KRAS;PTGS2 GO:0006629| lipid metabolic process FDPS;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;KRAS 38623:[DB00480 DB08053] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08053|1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:1902533| TNFSF11;SRC GO:0098609| CDH5;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0034332| adherens junction organization CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0070542| response to fatty acid SRC;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 38624:[DB00480 DB06090] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06090|Bradanicline CHRNA7 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0007613| memory PTGS2;CHRNA7 38625:[DB00480 DB01614] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0042493| response to drug HTR2A;DRD1;ADRA1A;DRD2;PTGS2;ABCB1 GO:0007612| learning DRD1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging ADRA1A;HTR2A;PTGS2 GO:0098869| ALB;PTGS2 GO:0007275| multicellular organismal development ADRA1B;TNFSF11 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2;ADRA1B GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;DRD2;PTGS2 GO:0007613| memory HTR2A;DRD1;PTGS2 GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;ADRA1A;HTR2A 38626:[DB00480 DB13151] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0010469| regulation of receptor activity F2;TNFSF11 GO:0032355| response to estradiol stimulus F7;PTGS2 GO:0008284| positive regulation of cell proliferation F2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;F8 GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11;F7 GO:0045907| positive regulation of vasoconstriction FGB;PTGS2;FGA GO:0014070| response to organic cyclic compound PTGS2;F7 GO:0007275| multicellular organismal development F2;TNFSF11 38627:[DB00480 DB00475] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006810| transport GABRA4;GABRA6;GABRB1;GABRD;GABRB2;GABRA5;GABRA3;GABRG2;ABCB1;GABRA1;GABRB3 GO:0042493| response to drug GABRG3;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38628:[DB00480 DB11914] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11914|Lebrikizumab IL13;IL13 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;IL13 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;IL13 GO:0010469| regulation of receptor activity TNFSF11;IL13 GO:0071260| cellular response to mechanical stimulus PTGS2;IL13 GO:0006955| immune response TNFSF11;IL13 GO:0006954| inflammatory response PTGS2;IL13 38629:[DB00480 DB01382] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0007613| memory ABCC8;PTGS2 GO:0032496| response to lipopolysaccharide ABCC8;PTGS2 GO:0042493| response to drug ABCC8;PTGS2;ABCB1 GO:0055085| transmembrane transport ABCC8;ABCB1 38630:[DB00480 DB07448] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07448|(2S)-3-[(R)-[(1S)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]-2-benzylpropanoic acid LAP3 common genes common pathways 38631:[DB00480 DB03279] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03279|Dodecyl-Alpha-D-Maltoside RARG common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;RARG;CDH5 GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:1990830| TNFSF11;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RARG GO:0008284| positive regulation of cell proliferation RARG;PTGS2 38632:[DB00480 DB08836] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0008217| regulation of blood pressure ACE;PTGS2 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC15A1 GO:0006810| transport ABCB1;SLC15A1 38633:[DB00480 DB00714] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11;HTR2A;HTR2B GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007612| learning DRD5;DRD3;DRD1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR2A;HTR2B;HTR1A;PTGS2;ADRA2A;DRD3 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0042493| response to drug HTR1B;ABCB1;DRD3;HTR2C;PTGS2;HTR2B;DRD1;HTR2A;DRD2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0007613| memory PTGS2;DRD1;HTR2A GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA2C;HTR2A;PTGS2 GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B 38634:[DB00480 DB03495] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03495|4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose AMY2A;AMY2A common genes common pathways 38635:[DB00480 DB09099] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:1990830| SSTR1;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0008285| negative regulation of cell proliferation SSTR3;SSTR4;SSTR5;CDH5;PTGS2;SSTR2;SSTR1 38636:[DB00480 DB03223] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03223|Diphthamide EEF2 common genes common pathways GO:0042493| response to drug PTGS2;EEF2;ABCB1 GO:0007568| aging EEF2;PTGS2 GO:0032355| response to estradiol stimulus EEF2;PTGS2 38637:[DB00480 DB06843] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06843|2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE GNAS;ADCY2;ADCY5 common genes common pathways GO:0045672| positive regulation of osteoclast differentiation TNFSF11;GNAS GO:0042493| response to drug PTGS2;GNAS;ABCB1 38638:[DB00480 DB08675] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08675|(5Z)-7-{(1R,4S,5R,6R)-6-[(1E)-1-Octen-1-yl]-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl}-5-heptenoic acid PTGIS common genes common pathways GO:0001516| prostaglandin biosynthetic process PTGS2;PTGIS GO:0007566| embryo implantation PTGS2;PTGIS GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGIS;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGIS GO:0019371| cyclooxygenase pathway PTGS2;PTGIS GO:0006693| prostaglandin metabolic process PTGIS;PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGIS GO:0046697| decidualization PTGS2;PTGIS GO:0071456| cellular response to hypoxia PTGIS;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGIS GO:0055114| oxidation-reduction process PTGS2;PTGIS GO:0050728| negative regulation of inflammatory response PTGIS;CDH5 38639:[DB00480 DB00926] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00926|Etretinate RARA;RXRA;RARB;RXRG;RXRB;RARG;CYP19A1;CYP26A1;CRABP1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;PTGS2;CYP26A1 GO:0043066| negative regulation of apoptotic process RARG;RARA;PTGS2;RARB GO:0008284| positive regulation of cell proliferation RARG;RARA;PTGS2;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RXRB;RXRA;RARB;RARG;RXRG;RARA GO:0034097| response to cytokine stimulus RARA;PTGS2 GO:1990830| TNFSF11;RARG GO:0032355| response to estradiol stimulus PTGS2;RARA GO:0007275| multicellular organismal development CRABP1;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;RARG;RARB GO:0008285| negative regulation of cell proliferation PTGS2;RARA;RARG;RARB;CDH5 GO:0007566| embryo implantation RXRA;PTGS2 38640:[DB00480 DB11611] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11611|Lifitegrast ITGAL;CYP2C9;SLCO1A2;SLCO2B1 common genes common pathways GO:0007155| cell adhesion CDH5;ITGAL GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0098609| CDH5;ITGAL GO:0055085| transmembrane transport SLCO2B1;SLCO1A2;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0006954| inflammatory response ITGAL;PTGS2 38641:[DB00480 DB06699] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06699|Degarelix GNRHR common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GNRHR 38642:[DB00480 DB05687] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging PTGS2;HTR2A GO:0042493| response to drug PTGS2;HTR2A;DRD2;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0007613| memory PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0019233| sensory perception of pain PTGS2;HTR2A 38643:[DB00480 DB03314] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03314|Fluorotryptophane TPI1;GSTM1 common genes common pathways GO:0007275| multicellular organismal development TPI1;TNFSF11 38644:[DB00480 DB01400] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01400|Neostigmine ACHE;BCHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE 38645:[DB00480 DB04972] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04972|Canfosfamide GSTP1 common genes common pathways GO:0098869| PTGS2;GSTP1 GO:0032355| response to estradiol stimulus PTGS2;GSTP1 GO:0043066| negative regulation of apoptotic process PTGS2;GSTP1 38646:[DB00480 DB04774] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04774|Reidispongiolide A ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 38647:[DB00480 DB05578] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05578|Ramucirumab KDR common genes common pathways GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0001525| angiogenesis KDR;PTGS2 GO:0030154| cell differentiation TNFSF11;KDR GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0008284| positive regulation of cell proliferation PTGS2;KDR 38648:[DB00480 DB07187] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07187|6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 38649:[DB00480 DB03974] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03974|L-Homoarginine NOS3 common genes common pathways GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process NOS3;PTGS2 38650:[DB00480 DB09564] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09564|Insulin Degludec INSR common genes common pathways GO:0007613| memory INSR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR GO:0009887| organ morphogenesis INSR;TNFSF11 GO:0008284| positive regulation of cell proliferation INSR;PTGS2 GO:0007612| learning PTGS2;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 38651:[DB00480 DB14517] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TNFSF11 GO:0007613| memory PTGS2;APP GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;APP GO:0008285| negative regulation of cell proliferation PTGS2;APP;CDH5 GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0046330| positive regulation of JNK cascade APP;TNFSF11 GO:0007612| learning PTGS2;APP GO:0007155| cell adhesion CDH5;APP GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;APP GO:0042493| response to drug PTGS2;ATP1A1;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;APP GO:0006979| response to oxidative stress PTGS2;APP GO:0098869| ALB;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;PTGS2 GO:0051260| protein homooligomerization TNFSF11;APP 38652:[DB00480 DB03476] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03476|Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine PLAU common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PLAU GO:0042127| regulation of cell proliferation PLAU;PTGS2 38653:[DB00480 DB02633] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02633|Cibacron Blue NQO1;GSTP1 common genes common pathways GO:0006979| response to oxidative stress NQO1;PTGS2 GO:0098869| PTGS2;GSTP1 GO:0032355| response to estradiol stimulus NQO1;PTGS2;GSTP1 GO:0007568| aging NQO1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;GSTP1;NQO1 GO:0055114| oxidation-reduction process PTGS2;NQO1 GO:0014070| response to organic cyclic compound PTGS2;NQO1 38654:[DB00480 DB08166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08166|(4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;PTGS2 GO:0007275| multicellular organismal development PIM1;TNFSF11 38655:[DB00480 DB06931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06931|(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 38656:[DB00480 DB01289] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways GO:0032496| response to lipopolysaccharide KCNJ8;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;PTGS2 GO:0006629| lipid metabolic process CYP2C9;PTGS2 38657:[DB00480 DB00357] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP11A1;PTGS2 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP19A1;CYP11A1;CYP3A4 38658:[DB00480 DB08176] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08176|(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE MAOB common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOB GO:0042493| response to drug ABCB1;PTGS2;MAOB GO:0032496| response to lipopolysaccharide PTGS2;MAOB 38659:[DB00480 DB13144] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13144|Lenograstim CSF3R common genes common pathways GO:0007155| cell adhesion CDH5;CSF3R GO:0019221| cytokine-mediated signaling pathway CSF3R;TNFSF11 38660:[DB00480 DB08104] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08104|N-(3,5-dibromo-4-hydroxyphenyl)benzamide TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport ABCB1;TTR 38661:[DB00480 DB04334] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;AOC3 GO:0007155| cell adhesion AOC3;CDH5 GO:0006954| inflammatory response PTGS2;AOC3 38662:[DB00480 DB14041] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14041|Fremanezumab CALCA;CALCB common genes common pathways GO:0008217| regulation of blood pressure CALCA;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;CALCB;CALCA 38663:[DB00480 DB07061] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07061|1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL NMT2 common genes common pathways 38664:[DB00480 DB05265] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05265|Ecabet NOXO1;ureC common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOXO1 38665:[DB00480 DB09309] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09309|Kitasamycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38666:[DB00480 DB05479] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05479|CZEN 002 MC1R common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MC1R GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;MC1R GO:0007275| multicellular organismal development MC1R;TNFSF11 38667:[DB00480 DB01677] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01677|Fumaric Acid mdh;ME2;FAH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ME2 38668:[DB00480 DB01056] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0098869| PTGS2;ALB GO:0055085| transmembrane transport ABCB1;SCN5A GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 38669:[DB00480 DB04876] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04876|Vildagliptin DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 38670:[DB00480 DB02393] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02393|D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate PFKFB1 common genes common pathways GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 38671:[DB00480 DB08057] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08057|N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine LCK common genes common pathways GO:0050870| positive regulation of T cell activation LCK;TNFSF11 GO:0042493| response to drug LCK;PTGS2;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade LCK;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;LCK 38672:[DB00480 DB07766] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07766|(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} CAMK2A;CDK16 common genes common pathways GO:0030154| cell differentiation CAMK2A;TNFSF11;CDK16 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CAMK2A 38673:[DB00480 DB00976] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00976|Telithromycin CYP3A7;CYP3A4;CYP3A5;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP3A5;CYP3A7 GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1B1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38674:[DB00480 DB11093] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11093|Calcium Citrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;CIB1;PTGS2 GO:0014070| response to organic cyclic compound CASR;PTGS2 GO:0045907| positive regulation of vasoconstriction CASR;PTGS2 GO:0019722| calcium-mediated signaling RYR2;TNFSF11 GO:0051384| response to glucocorticoid stimulus S100B;SPARC;PTGS2 GO:0030154| cell differentiation TPT1;CIB1;TNFSF11;CATSPER1;CALR3 GO:0007613| memory S100B;PTGS2 GO:0055074| calcium ion homeostasis TNFSF11;CALB1;TRPV6;SLC8A1;CIB2;TRPV5 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CIB1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis CIB1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;S100B GO:0001503| ossification CASR;SPARC;TNFSF11 GO:0007275| multicellular organismal development RYR2;RYR1;CATSPER1;TNFSF11 GO:0001525| angiogenesis PDCD6;PTGS2;CIB1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100A13;S100B;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;NRXN1 GO:0010033| response to organic substance CASQ1;PTGS2;CALR GO:0055085| transmembrane transport CACNA1G;CACNA1E;TRPV6;CACNA1I;CACNA1A;CATSPER1;ABCB1;CACNA1F;RYR1;TRPV5;RYR3;CACNA1D;SLC8A1;CACNA1C;CACNA1S;RYR2;CACNA1H;CALM1 GO:0098869| ALB;PTGS2 GO:0034605| cellular response to heat PTGS2;PDCD6 GO:0032355| response to estradiol stimulus PTGS2;CALR GO:0007568| aging RGN;CANX;PTGS2 GO:0006810| transport SRI;CACNB1;CACNB3;CACNB4;CACNA1I;CACNA1E;ABCB1 GO:0071456| cellular response to hypoxia S100B;PTGS2;SLC8A1;CASR GO:0042493| response to drug CALR;PTGS2;SLC8A1;ABCB1 GO:0043066| negative regulation of apoptotic process CIB1;RGN;ALB;PTGS2;TPT1 GO:0008284| positive regulation of cell proliferation S100A13;PTGS2;CALR;CASR;S100B;CIB1 GO:0007155| cell adhesion CDH5;CIB1;NRXN1 GO:0034097| response to cytokine stimulus SPARC;PTGS2 GO:0071318| cellular response to ATP PTGS2;RYR3;CIB2 GO:0042127| regulation of cell proliferation CIB1;PTGS2;SPARC GO:0007612| learning PTGS2;NRXN1 GO:0032496| response to lipopolysaccharide PTGS2;SPARC 38675:[DB00480 DB12110] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12110|m-Chlorophenylpiperazine HTR2C common genes common pathways GO:0042493| response to drug HTR2C;ABCB1;PTGS2 38676:[DB00480 DB08358] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08358|2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0032496| response to lipopolysaccharide MAPKAPK2;PTGS2;MAPKAPK3 GO:0034097| response to cytokine stimulus MAPKAPK3;MAPKAPK2;PTGS2 GO:0006954| inflammatory response MAPKAPK2;PTGS2 38677:[DB00480 DB01354] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007613| memory PTGS2;CHRNA7 GO:0019233| sensory perception of pain PTGS2;CHRNA4 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0006810| transport GRIK2;GABRA6;GABRA4;GABRA3;GABRA5;ABCB1;GABRA1 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 38678:[DB00480 DB05225] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05225|AM103 ALOX5AP common genes common pathways GO:0019372| lipoxygenase pathway ALOX5AP;PTGS2 38679:[DB00480 DB11948] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11948|Lapachone RBP3 common genes common pathways GO:0006629| lipid metabolic process RBP3;PTGS2 38680:[DB00480 DB03672] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03672|9-N-Phenylmethylamino-Tacrine BCHE common genes common pathways GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 38681:[DB00480 DB01255] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006810| transport SLC15A1;ABCB1 GO:0055085| transmembrane transport SLC15A1;ABCB1 38682:[DB00480 DB07004] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07004|2-[(5-hex-1-yn-1-ylfuran-2-yl)carbonyl]-N-methylhydrazinecarbothioamide S100B common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;S100B GO:0051384| response to glucocorticoid stimulus PTGS2;S100B GO:0007613| memory S100B;PTGS2 GO:0008284| positive regulation of cell proliferation S100B;PTGS2 GO:0071456| cellular response to hypoxia S100B;PTGS2 38683:[DB00480 DB04327] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04327|Phosphatidylethanolamine PROCR;PTEN common genes common pathways GO:0007613| memory PTEN;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PTEN GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;PTEN GO:0001525| angiogenesis PTGS2;PTEN GO:0006629| lipid metabolic process PTEN;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PTEN GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PTEN;TNFSF11 GO:0007568| aging PTGS2;PTEN GO:0071456| cellular response to hypoxia PTEN;PTGS2 GO:0032355| response to estradiol stimulus PTEN;PTGS2 GO:0010033| response to organic substance PTGS2;PTEN GO:0043066| negative regulation of apoptotic process PTGS2;PTEN GO:0008284| positive regulation of cell proliferation PTEN;PTGS2 GO:0042493| response to drug ABCB1;PTEN;PTGS2 38684:[DB00480 DB03206] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03206|Duvoglustat MAN1B1;xylA common genes common pathways 38685:[DB00480 DB03389] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03389|alpha-D-Xylopyranose LCT common genes common pathways 38686:[DB00480 DB08048] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08048|4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL ESR1;NCOA2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;NCOA2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 38687:[DB00480 DB08688] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08688|undecan-2-one ACOT13 common genes common pathways 38688:[DB00480 DB01202] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes ABCB1 common pathways GO:0006810| transport CACNA1B;ABCC2;ABCB1 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0055085| transmembrane transport SV2A;CACNA1B;ABCB1;ABCC2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:1901529| ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCC2;ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0008217| regulation of blood pressure CACNA1B;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38689:[DB00480 DB06880] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06880|(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion DPP4;CDH5 38690:[DB00480 DB08693] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08693|L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 38691:[DB00480 DB00127] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00127|Spermine SMS;SMOX;ODC1;CASR;ADRB1;ADRB2;XDH;SAT1;SAT2;SLC22A4;SLC22A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A1;SLC22A4 GO:0071456| cellular response to hypoxia PTGS2;CASR GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0055114| oxidation-reduction process SMOX;PTGS2;XDH GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0042127| regulation of cell proliferation SAT1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0008284| positive regulation of cell proliferation ODC1;CASR;PTGS2 GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0014070| response to organic cyclic compound PTGS2;CASR GO:0045907| positive regulation of vasoconstriction CASR;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0050873| brown fat cell differentiation ADRB1;PTGS2;ADRB2 GO:0001525| angiogenesis PTGS2;SAT1 GO:0001503| ossification CASR;TNFSF11 38692:[DB00480 DB09238] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP2C9;CYP3A4 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0042493| response to drug ABCB1;PTGS2;CYP1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP2B6;CYP2C9;CYP2C19;PTGS2;CYP1A1 GO:0006810| transport CACNB3;CACNB1;CACNB4;CACNA1I;ABCB1 GO:0007568| aging CYP1A1;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0055085| transmembrane transport CACNA1I;CACNA1G;ABCB1;CACNA1F;CACNA1D;CACNA1C;CACNA1H;CACNA1S 38693:[DB00480 DB07382] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07382|N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine ERN1 common genes common pathways GO:0007257| activation of JUN kinase activity TNFSF11;ERN1 38694:[DB00480 DB01712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01712|(3r)-4-(P-Toluenesulfonyl)-1,4-Thiazane-3-Carboxylicacid-L-Phenylalanine Ethyl Ester FKBP1A common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TNFSF11 38695:[DB00480 DB00301] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0006810| transport ABCB11;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38696:[DB00480 DB00547] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00547|Desoximetasone NR3C1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 38697:[DB00480 DB04835] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04835|Maraviroc CCR5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006955| immune response TNFSF11;CCR5 GO:0006954| inflammatory response PTGS2;CCR5 GO:0019722| calcium-mediated signaling TNFSF11;CCR5 38698:[DB00480 DB00868] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00868|Benzonatate SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 38699:[DB00480 DB07795] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07795|Fisetin CDK6 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;CDK6;PTGS2 GO:0030154| cell differentiation CDK6;TNFSF11 GO:0045786| negative regulation of cell cycle CDK6;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;CDK6 38700:[DB00480 DB03096] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03096|N-Aminoethylmorpholine CTSD common genes common pathways 38701:[DB00480 DB12731] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12731|Daporinad NAMPT common genes common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway NAMPT;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;NAMPT GO:0010469| regulation of receptor activity NAMPT;TNFSF11 GO:0008284| positive regulation of cell proliferation NAMPT;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NAMPT GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;NAMPT 38702:[DB00480 DB07201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07201|(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TNFSF11;TTR 38703:[DB00480 DB05077] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05077|SLV319 CNR1 common genes common pathways GO:0019233| sensory perception of pain CNR1;PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0043065| positive regulation of apoptotic process CNR1;PTGS2 GO:0007613| memory PTGS2;CNR1 GO:0032496| response to lipopolysaccharide CNR1;PTGS2 GO:0007568| aging CNR1;PTGS2 38704:[DB00480 DB05446] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05446|LJP 1082 APOH common genes common pathways 38705:[DB00480 DB06963] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 GO:0016567| protein ubiquitination CRBN;PLK1 GO:0043066| negative regulation of apoptotic process PTGS2;PLK1 38706:[DB00480 DB00893] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways GO:0006955| immune response FTH1;TNFSF11 GO:0010942| positive regulation of cell death HBB;PTGS2;HBA1 GO:0008285| negative regulation of cell proliferation FTH1;PTGS2;CDH5 GO:0008217| regulation of blood pressure HBB;PTGS2 GO:0055114| oxidation-reduction process PTGS2;FTH1 GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;PTGS2 GO:0098869| HBB;PTGS2;HBA1 38707:[DB00480 DB00128] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00128|L-Aspartic Acid RNASE1;LYZ;SLC25A13;GOT1;ASPA;ASNS;ASS1;ACY1;GOT2;DARS;SLC25A12;ASPH;PAICS;CAD;ADSS;SLC1A1;GIG18;ASS;DARS2;ASRGL1;ADSSL1;ACY3;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC25A13;SLC16A10;SLC25A12;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process ASS1;PTGS2 GO:0051260| protein homooligomerization SLC1A1;TNFSF11 GO:0055114| oxidation-reduction process ASPH;PTGS2 GO:0043066| negative regulation of apoptotic process ASNS;PTGS2 GO:0008285| negative regulation of cell proliferation ASPH;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus GOT1;PTGS2 GO:0006954| inflammatory response LYZ;PTGS2 38708:[DB00480 DB06321] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06321|R-348 JAK3 common genes common pathways GO:0006954| inflammatory response JAK3;PTGS2 38709:[DB00480 DB02281] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02281|Formycin MTAP common genes common pathways 38710:[DB00480 DB02598] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02598|N-Alpha-Acetyl-3,5-Diiodotyrosylglycine PAM common genes common pathways GO:0051260| protein homooligomerization PAM;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;PAM GO:0055114| oxidation-reduction process PAM;PTGS2 GO:0042493| response to drug PAM;ABCB1;PTGS2 GO:0051384| response to glucocorticoid stimulus PAM;PTGS2 38711:[DB00480 DB05209] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05209|SYM001 RHD common genes common pathways 38712:[DB00480 DB04437] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04437|Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline FABP4 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0050727| regulation of inflammatory response FABP4;PTGS2 38713:[DB00480 DB14639] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14639|Boldenone undecylenate AR common genes common pathways GO:0006810| transport ABCB1;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 38714:[DB00480 DB00757] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00757|Dolasetron HTR3A;CYP3A4;CYP2D6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6;CYP2C9 38715:[DB00480 DB07231] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07231|N-({(2S,3S)-3-[(BENZYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINE CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 38716:[DB00480 DB06802] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06802|Nepafenac PTGS1;PTGS2 common genes PTGS2 common pathways GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0098869| PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 38717:[DB00480 DB01764] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38718:[DB00480 DB06144] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0055085| transmembrane transport KCNH2;ABCB1 GO:0007568| aging PTGS2;HTR2A;ADRA1A GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0042493| response to drug HTR2A;DRD2;ADRA1A;PTGS2;HTR2C;ABCB1 GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2;ADRA1D GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;DRD2;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0045907| positive regulation of vasoconstriction ADRA1D;PTGS2;ADRA1B;ADRA1A;HTR2A GO:0007613| memory HTR2A;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D GO:0019233| sensory perception of pain PTGS2;HTR2A 38719:[DB00480 DB00797] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;ADRA2A GO:0042493| response to drug ABCB1;ADRA1A;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0007568| aging ADRA1A;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0006954| inflammatory response HRH1;PTGS2 GO:0006955| immune response HRH2;TNFSF11 GO:0007613| memory HRH2;PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A;HRH2;ADRA2C;HRH1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 38720:[DB00480 DB00345] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2;ABCC2;ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:0055085| transmembrane transport SLC22A4;ABCB1;ABCC2;SLC16A1;SLCO3A1;SLCO1A2;SLC22A11;ABCC1;SLC22A5;SLC22A8;SLCO1B1;SLC22A7;SLC22A6;SLC22A2 GO:0006810| transport ABCC1;ABCC2;ABCB1 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006629| lipid metabolic process SLC16A1;PTGS2 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A5;ABCC2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 38721:[DB00480 DB02783] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 38722:[DB00480 DB07628] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07628|6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one PKM common genes common pathways GO:0010033| response to organic substance PKM;PTGS2 38723:[DB00480 DB07895] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07895|ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID FNTB;FNTA common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;FNTB GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CDH5 38724:[DB00480 DB06444] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06444|Dexanabinol TNF common genes common pathways GO:0009887| organ morphogenesis TNFSF11;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2 GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0010469| regulation of receptor activity TNF;TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TNF GO:0042127| regulation of cell proliferation TNF;PTGS2 GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0006955| immune response TNF;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0006954| inflammatory response TNF;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;TNF GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0007275| multicellular organismal development TNFSF11;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0031622| positive regulation of fever generation TNF;PTGS2 38725:[DB00480 DB05595] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05595|Farletuzumab FOLR1 common genes common pathways 38726:[DB00480 DB08174] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08174|5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 38727:[DB00480 DB06103] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06103|VX-148 IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process IMPDH2;PTGS2;IMPDH1 38728:[DB00480 DB00061] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00061|Pegademase bovine GRB2 common genes common pathways GO:0030154| cell differentiation TNFSF11;GRB2 GO:0007568| aging GRB2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GRB2;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;GRB2 38729:[DB00480 DB07002] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07002|4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;PTGS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 38730:[DB00480 DB01113] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01113|Papaverine PDE4B;PDE10A common genes common pathways 38731:[DB00480 DB07364] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07364|6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE CDK5;CDK5R1 common genes common pathways GO:0045786| negative regulation of cell cycle CDK5;PTGS2 GO:0019233| sensory perception of pain CDK5;PTGS2 38732:[DB00480 DB05758] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05758|CYT007-TNFQb TNF common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;TNF GO:0043065| positive regulation of apoptotic process PTGS2;TNF GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0006954| inflammatory response TNF;PTGS2 GO:0006955| immune response TNF;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0010469| regulation of receptor activity TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0009887| organ morphogenesis TNFSF11;TNF GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;TNFSF11 GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF 38733:[DB00480 DB07081] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07081|(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion CDH5;DPP4 38734:[DB00480 DB07683] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07683|N-(dibenzo[b,d]thiophen-3-ylsulfonyl)-L-valine MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 38735:[DB00480 DB02681] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02681|2,8-bis[oxido(oxo)vanadio]-1,1,1,3,5,5,7,7,9,9,9-undecaoxopentavanadoxane-2,8-diium CKS1B common genes common pathways 38736:[DB00480 DB00205] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00205|Pyrimethamine DHFR;HEXB;CYP2C8;SLC47A1;SLC47A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HEXB GO:0055114| oxidation-reduction process PTGS2;DHFR;CYP2C8 GO:0055085| transmembrane transport SLC47A1;SLC47A2;ABCB1 GO:0006855| drug transmembrane transport SLC47A1;ABCB1;SLC47A2 38737:[DB00480 DB06495] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06495|Onercept TNF common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0010033| response to organic substance PTGS2;TNF GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0046330| positive regulation of JNK cascade TNFSF11;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TNF GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0006954| inflammatory response PTGS2;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0006955| immune response TNFSF11;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF 38738:[DB00480 DB01897] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01897|2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride HPGDS common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0001516| prostaglandin biosynthetic process HPGDS;PTGS2 GO:0006629| lipid metabolic process HPGDS;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;HPGDS GO:0019371| cyclooxygenase pathway HPGDS;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;HPGDS 38739:[DB00480 DB01621] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory PTGS2;HTR2A;DRD1 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0098869| PTGS2;ALB GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0007568| aging PTGS2;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC22A1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2;HTR1A GO:0007612| learning DRD1;PTGS2 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP2D6;CYP3A4 GO:0042493| response to drug ABCB1;HTR2A;DRD1;DRD2;PTGS2 38740:[DB00480 DB11471] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11471|Tilmicosin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38741:[DB00480 DB04844] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0055085| transmembrane transport SLC18A2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0042493| response to drug ABCB1;PTGS2;DRD2 GO:0055114| oxidation-reduction process CYP2D6;CBR1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0019371| cyclooxygenase pathway CBR1;PTGS2 38742:[DB00480 DB08067] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08067|4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM JAK2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;JAK2 GO:0050727| regulation of inflammatory response PTGS2;JAK2 GO:0008285| negative regulation of cell proliferation JAK2;PTGS2;CDH5 GO:0030154| cell differentiation JAK2;TNFSF11 GO:0019221| cytokine-mediated signaling pathway TNFSF11;JAK2 GO:0032496| response to lipopolysaccharide JAK2;PTGS2 GO:0042127| regulation of cell proliferation JAK2;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;JAK2 GO:0034612| response to tumor necrosis factor PTGS2;JAK2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;JAK2 GO:0045429| positive regulation of nitric oxide biosynthetic process JAK2;PTGS2 GO:0006979| response to oxidative stress PTGS2;JAK2 38743:[DB00480 DB00425] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0098869| PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006810| transport GABRA3;GABRB3;GABRA1;ABCB1;GABRG2 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2D6;CYP2C9;PTGS2;CYP2C19;PTGS1;CYP3A7;CYP3A5 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process CYP1A2;CYP2D6;CYP2C9;CYP3A4;PTGS1;PTGS2 38744:[DB00480 DB02342] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02342|2-Methoxyestradiol HIF1A;COMT;CYP1A1;CYP1B1;CYP19A1;SHBG common genes common pathways GO:0010033| response to organic substance CYP1A1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;HIF1A GO:0007568| aging PTGS2;CYP1A1 GO:0016567| protein ubiquitination CRBN;HIF1A GO:0042493| response to drug COMT;ABCB1;CYP1A1;PTGS2 GO:0055114| oxidation-reduction process CYP19A1;CYP1B1;CYP1A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HIF1A GO:0043066| negative regulation of apoptotic process PTGS2;HIF1A GO:0007155| cell adhesion CYP1B1;CDH5 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2;COMT GO:0007612| learning COMT;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;HIF1A GO:0008285| negative regulation of cell proliferation PTGS2;CYP1B1;CDH5 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1;COMT GO:0030154| cell differentiation TNFSF11;HIF1A GO:0043065| positive regulation of apoptotic process PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production HIF1A;PTGS2;CYP1B1 GO:0001525| angiogenesis CYP1B1;PTGS2;HIF1A 38745:[DB00480 DB14502] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade SLC20A1;TNFSF11 GO:0001503| ossification TNFSF11;SLC34A1 GO:0042493| response to drug PTGS2;SLC34A1;ABCB1 GO:0006810| transport ABCB1;SLC20A2;SLC20A1 GO:0032355| response to estradiol stimulus PTGS2;SLC34A1 GO:0051260| protein homooligomerization SLC34A1;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC34A3;SLC34A2;SLC20A2;SLC20A1 38746:[DB00480 DB02417] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02417|2,4,6-Tribromophenol TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport ABCB1;TTR 38747:[DB00480 DB14013] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14013|SR-9009 NR1D1;NR1D2 common genes common pathways GO:0050727| regulation of inflammatory response NR1D2;PTGS2 GO:0030154| cell differentiation TNFSF11;NR1D1 38748:[DB00480 DB07410] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07410|[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID GGPS1;ispU common genes common pathways 38749:[DB00480 DB03542] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 38750:[DB00480 DB11979] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes ABCB1 common pathways GO:0007275| multicellular organismal development GNRHR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP3A43;CYP2D6;CYP2C8;PTGS2;CYP3A5;CYP3A7 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport SLCO1B1;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 38751:[DB00480 DB06510] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP1A2 GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0042493| response to drug PTGS2;UGT1A1;ABCB1;PPARG;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TNFSF11 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2;UGT1A1 GO:0010033| response to organic substance CYP1A2;PPARG;UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG;PPARA;CYP1A2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0014070| response to organic cyclic compound PPARG;CYP1A2;PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 38752:[DB00480 DB00507] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00507|Nitazoxanide SLC19A1 common genes common pathways 38753:[DB00480 DB07776] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0045670| regulation of osteoclast differentiation ESRRA;TNFSF11 GO:0032355| response to estradiol stimulus ESRRA;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1B1 GO:0007155| cell adhesion CDH5;CYP1B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRA;ESRRB;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;ESRRA GO:0008285| negative regulation of cell proliferation CYP1B1;CDH5;PTGS2 GO:0043065| positive regulation of apoptotic process CYP1B1;PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 38754:[DB00480 DB06689] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06689|Ethanolamine oleate F12;CYP2E1 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1 GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 38755:[DB00480 DB00922] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0042493| response to drug ABCB1;PDE3A;PTGS2;KCNJ11 GO:0032496| response to lipopolysaccharide PTGS2;KCNJ8 GO:0043066| negative regulation of apoptotic process PDE3A;PTGS2 GO:0055085| transmembrane transport ABCB1;KCNJ11 GO:0032355| response to estradiol stimulus PTGS2;KCNJ11 GO:0006629| lipid metabolic process PTGS2;PDE3A 38756:[DB00480 DB01176] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 38757:[DB00480 DB09328] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0014070| response to organic cyclic compound ACAT1;PTGS2;CYP1A2 GO:0006633| fatty acid biosynthetic process FADS1;ELOVL4;PTGS2 GO:0006629| lipid metabolic process FADS1;CYP1A2;ACAA1;ELOVL4;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0051260| protein homooligomerization TNFSF11;ACAT1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0006631| fatty acid metabolic process ACAA1;ELOVL4;FADS1;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP1A2;FADS1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 38758:[DB00480 DB03597] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03597|Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine PDE9A;PDE5A;GSTM4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity PDE5A;TNFSF11 38759:[DB00480 DB04857] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04857|Brasofensine DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 38760:[DB00480 DB02661] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02661|Adenosine-5'-Diphosphate-2',3'-Vanadate PAPSS1 common genes common pathways 38761:[DB00480 DB08229] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08229|[N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID CASP3 common genes common pathways GO:0032496| response to lipopolysaccharide CASP3;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process CASP3;PTGS2 GO:0042493| response to drug ABCB1;CASP3;PTGS2 GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0010033| response to organic substance PTGS2;CASP3 GO:0043065| positive regulation of apoptotic process PTGS2;CASP3 GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CASP3 38762:[DB00480 DB02079] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02079|Aminooxyacetic acid AGXT common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;AGXT 38763:[DB00480 DB05524] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05524|Pelitinib EGFR common genes common pathways GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 GO:0014070| response to organic cyclic compound EGFR;PTGS2 GO:0007275| multicellular organismal development TNFSF11;EGFR GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification EGFR;TNFSF11 GO:0098609| CDH5;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0006979| response to oxidative stress PTGS2;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;EGFR GO:0043066| negative regulation of apoptotic process EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR 38764:[DB00480 DB11155] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0007568| aging CYP1A1;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0007155| cell adhesion CYP1B1;CDH5 GO:0042493| response to drug ABCB1;CYP1A1;PTGS2 GO:0055114| oxidation-reduction process CYP1A1;PTGS2;CYP1B1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0008285| negative regulation of cell proliferation CDH5;CYP1B1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CYP1B1 38765:[DB00480 DB00348] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00348|Nitisinone HPD common genes common pathways GO:0055114| oxidation-reduction process HPD;PTGS2 38766:[DB00480 DB11644] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11644|Tafamidis TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport ABCB1;TTR 38767:[DB00480 DB03217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03217|DPI59 SRC common genes common pathways GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| CDH5;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC 38768:[DB00480 DB11751] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCB1 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 38769:[DB00480 DB02076] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02076|6-phospho-D-gluconic acid PGD;GPI common genes common pathways GO:0032355| response to estradiol stimulus GPI;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;GPI GO:0055114| oxidation-reduction process PTGS2;PGD GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPI GO:0001525| angiogenesis PTGS2;GPI 38770:[DB00480 DB08373] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08373|4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL SCGB1A1 common genes common pathways GO:0010033| response to organic substance PTGS2;SCGB1A1 GO:0042493| response to drug ABCB1;SCGB1A1;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;SCGB1A1 GO:0032496| response to lipopolysaccharide SCGB1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;SCGB1A1 GO:0007566| embryo implantation PTGS2;SCGB1A1 GO:0050727| regulation of inflammatory response PTGS2;SCGB1A1 38771:[DB00480 DB04911] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP3A4;PTGS2;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;PTGS2 38772:[DB00480 DB01338] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01338|Pipecuronium CHRNA2;CHRM2;CHRM3;BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE 38773:[DB00480 DB04512] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04512|2-Isobutyl-3-Methoxypyrazine LCN9 common genes common pathways 38774:[DB00480 DB06475] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06475|Ruplizumab CD40LG common genes common pathways GO:0006954| inflammatory response PTGS2;CD40LG GO:0051092| positive regulation of NF-kappaB transcription factor activity CD40LG;TNFSF11 GO:0006955| immune response TNFSF11;CD40LG GO:0007257| activation of JUN kinase activity TNFSF11;CD40LG GO:0043066| negative regulation of apoptotic process PTGS2;CD40LG GO:0010469| regulation of receptor activity TNFSF11;CD40LG GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;CD40LG 38775:[DB00480 DB04659] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04659|(1S,2S,3R,4S,5S)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 38776:[DB00480 DB04912] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04912|Stannsoporfin HMOX1;HMOX2 common genes common pathways GO:0008217| regulation of blood pressure HMOX1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;TNFSF11 GO:0001525| angiogenesis PTGS2;HMOX1 GO:0043065| positive regulation of apoptotic process PTGS2;HMOX1 GO:0071456| cellular response to hypoxia PTGS2;HMOX1 GO:0034605| cellular response to heat PTGS2;HMOX1 GO:0006979| response to oxidative stress HMOX1;PTGS2;HMOX2 GO:0051260| protein homooligomerization TNFSF11;HMOX1 GO:0055114| oxidation-reduction process HMOX1;PTGS2;HMOX2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMOX1 38777:[DB00480 DB07189] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07189|(1S,3R,6S)-4-oxo-6-{4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-5-azaspiro[2.4]heptane-1-carboxylic acid ADAM17 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;ADAM17 GO:0007155| cell adhesion ADAM17;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;ADAM17 GO:0032496| response to lipopolysaccharide PTGS2;ADAM17 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;ADAM17 38778:[DB00480 DB03642] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03642|Benzofuran-2-Carboxylic Acid {(S)-3-Methyl-1-[3-Oxo-1-(Pyridin-2-Ylsulfonyl)Azepan-4-Ylcarbamoyl]Butyl}Amide CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 38779:[DB00480 DB02685] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02685|3-Methylphenylalanine CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 38780:[DB00480 DB00670] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00670|Pirenzepine CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 38781:[DB00480 DB04878] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04878|Voglibose MGAM common genes common pathways 38782:[DB00480 DB00113] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways GO:0007156| homophilic cell adhesion CEACAM1;CDH5 GO:0007155| cell adhesion CDH5;CEACAM1 GO:0001525| angiogenesis PTGS2;CEACAM1 38783:[DB00480 DB11132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11132|Silicon dioxide MARCO common genes common pathways 38784:[DB00480 DB02048] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02048|1,2,4-Triazole-Carboxamidine NOS3 common genes common pathways GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 38785:[DB00480 DB09225] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory SLC6A4;DRD1;HTR2A;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging HTR2A;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4;CYP1A2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0010033| response to organic substance CYP1A2;SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC6A2;SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0007612| learning DRD5;PTGS2;DRD1 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;PTGS2 GO:0042493| response to drug DRD2;DRD1;HTR2A;SLC6A2;PTGS2;CYP1A2;ABCB1;SLC6A4 38786:[DB00480 DB09237] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;NOS2;NOS3;CYP3A4 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055085| transmembrane transport ABCB1;CACNA1C GO:0001525| angiogenesis PTGS2;NOS3 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 38787:[DB00480 DB04368] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04368|Bb-3497 def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;PDF 38788:[DB00480 DB03273] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03273|3'-Oxo-Adenosine AHCY common genes common pathways 38789:[DB00480 DB04214] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04214|4-Nitrophenyl Phosphate ACP1;DUSP23 common genes common pathways 38790:[DB00480 DB03078] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03078|PASBN SRC common genes common pathways GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0070542| response to fatty acid PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0098609| CDH5;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:1902533| SRC;TNFSF11 GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0034332| adherens junction organization SRC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0007155| cell adhesion SRC;CDH5 38791:[DB00480 DB05382] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05382|Iodine MT-ND5 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MT-ND5 GO:0010243| response to organic nitrogen MT-ND5;PTGS2 38792:[DB00480 DB06762] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06762|Pinacidil CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38793:[DB00480 DB02490] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02490|(Diaminomethyl-Methyl-Amino)-Acetic Acid CKM common genes common pathways 38794:[DB00480 DB02106] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02106|[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;THRB GO:0009887| organ morphogenesis THRB;TNFSF11 38795:[DB00480 DB08011] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08011|(3E)-5-fluoro-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-1H-indole-2,3-dione 3-oxime MAPK10 common genes common pathways 38796:[DB00480 DB07702] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07702|17alpha-Estriol NCOA5;ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;TNFSF11 38797:[DB00480 DB03539] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03539|2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose CHIT1 common genes common pathways GO:0006955| immune response CHIT1;TNFSF11 38798:[DB00480 DB02730] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02730|4-Methylthio-Alpha-D-Mannose AMY2B common genes common pathways 38799:[DB00480 DB00463] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007613| memory PTGS2;CHRNA7 GO:0019233| sensory perception of pain PTGS2;CHRNA4 GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport GABRA6;GRIK2;GABRA4;GABRB1;GABRD;GABRB2;GABRA5;GABRA3;GABRG2;ABCB1;GABRA1;GABRB3 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0042493| response to drug GABRG3;ABCB1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 38800:[DB00480 DB00680] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00680|Moricizine SCN5A common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCB1 38801:[DB00480 DB08035] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08035|1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE AR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 38802:[DB00480 DB03338] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03338|Heptyl-Beta-D-Glucopyranoside PPARD;FKBP1A common genes common pathways GO:0050728| negative regulation of inflammatory response PPARD;CDH5 GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0043066| negative regulation of apoptotic process PPARD;PTGS2 GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0010033| response to organic substance PPARD;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0046697| decidualization PPARD;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARD GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A GO:0007566| embryo implantation PPARD;PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 38803:[DB00480 DB00579] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging SLC6A3;PTGS2 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport SLC18A2;SLC6A2;SLC6A3;SLC6A4;ABCB1 GO:0042493| response to drug ABCB1;SLC6A4;SLC6A2;PTGS2;SLC6A3 GO:0007613| memory SLC6A4;PTGS2 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 38804:[DB00480 DB07354] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07354|2,3-DIMETHOXY-12H-[1,3]DIOXOLO[5,6]INDENO[1,2-C]ISOQUINOLIN-6-IUM TOP1 common genes common pathways GO:0042493| response to drug PTGS2;TOP1;ABCB1 38805:[DB00480 DB14581] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14581|CPI-1205 EZH2 common genes common pathways GO:0042127| regulation of cell proliferation EZH2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;EZH2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;EZH2 38806:[DB00480 DB04661] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04661|Cis-tetracosenoyl sulfatide CD1D common genes common pathways 38807:[DB00480 DB06283] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06283|Ziconotide CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38808:[DB00480 DB02343] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02343|3,6,9,12,15-Pentaoxaheptadecane murI;ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 38809:[DB00480 DB06990] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06990|4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;PTGS2 38810:[DB00480 DB08819] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08819|Tafluprost PTGFR;PTGS2 common genes PTGS2 common pathways GO:0006979| response to oxidative stress PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0032355| response to estradiol stimulus PTGFR;PTGS2 GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0007568| aging PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0008284| positive regulation of cell proliferation PTGFR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;PTGFR GO:0045786| negative regulation of cell cycle PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;PTGFR GO:0071318| cellular response to ATP PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0055114| oxidation-reduction process PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0008217| regulation of blood pressure PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 38811:[DB00480 DB06712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP2C19;CYP2C8;CYP2A6;CYP3A4 GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 GO:0055085| transmembrane transport CACNA1D;CACNA1C;CACNA1S;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38812:[DB00480 DB00627] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC5A8;SLCO2B1;SLC16A3;SLC22A5;SLC16A1;ABCB1 GO:0010243| response to organic nitrogen PTGS2;NNMT GO:0042493| response to drug NNMT;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway NNMT;SLC5A8;PTGS2 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006629| lipid metabolic process PTGS2;SLC16A1;CYP2D6 38813:[DB00480 DB00050] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GNRHR GO:0045670| regulation of osteoclast differentiation TNFSF11;LHCGR 38814:[DB00480 DB06732] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06732|beta-Naphthoflavone ESR1;ESRRA;NR2F1;AHR;CYP1B1;CYP1A2 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;ESRRA GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0007155| cell adhesion CDH5;CYP1B1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;ESRRA;AHR;NR2F1 GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP1B1 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0032355| response to estradiol stimulus CYP1A2;ESR1;ESRRA;PTGS2 GO:0045670| regulation of osteoclast differentiation ESRRA;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;CYP1B1 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0043065| positive regulation of apoptotic process CYP1B1;PTGS2 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;CYP1B1 38815:[DB00480 DB00341] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00341|Cetirizine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2 38816:[DB00480 DB05983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;NFKBIA GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKBIA;TNFSF11 GO:0043066| negative regulation of apoptotic process NFKBIA;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NFKBIA GO:0032496| response to lipopolysaccharide NFKBIA;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway NFKBIA;TNFSF11 38817:[DB00480 DB09336] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways GO:0098609| CDH5;EPCAM GO:0008284| positive regulation of cell proliferation EPCAM;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EPCAM 38818:[DB00480 DB09532] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09532|Secretin human SCTR common genes common pathways 38819:[DB00480 DB04100] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0006810| transport ABCC2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0032496| response to lipopolysaccharide ABCC2;PTGS2 GO:0042493| response to drug ABCB1;ABCC2;PTGS2 38820:[DB00480 DB03041] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03041|UDP-alpha-D-glucuronic acid B3GAT3;GALE common genes common pathways 38821:[DB00480 DB03556] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03556|2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 CBR1;CBR1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CBR1 GO:0019371| cyclooxygenase pathway CBR1;PTGS2 38822:[DB00480 DB04151] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04151|4-Methyl-Histidine ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 38823:[DB00480 DB00126] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;DBH GO:0051384| response to glucocorticoid stimulus PAM;PTGS2 GO:0007613| memory DBH;PTGS2 GO:0008285| negative regulation of cell proliferation P3H1;PTGS2;CDH5;P3H2;P3H3 GO:0051260| protein homooligomerization TNFSF11;PAM GO:0032355| response to estradiol stimulus PAM;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC23A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGLN1;TNFSF11 GO:0042127| regulation of cell proliferation EGLN3;PTGS2;DBH GO:0006631| fatty acid metabolic process PTGS2;PHYH GO:0042493| response to drug PTGS2;PAM;ABCB1 GO:0055114| oxidation-reduction process P3H3;PLOD1;P3H2;OGFOD1;EGLN2;P4HTM;TMLHE;PAM;ALKBH2;DBH;PLOD3;PLOD2;EGLN1;P4HA1;P3H1;ALKBH3;PTGS2;KDM5D;EGLN3;BBOX1;PHYH;OGFOD2 38824:[DB00480 DB03442] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03442|2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid ATIC common genes common pathways 38825:[DB00480 DB09413] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09413|Monopotassium phosphate ALPI common genes common pathways 38826:[DB00480 DB06360] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06360|Lucatumumab CD40 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;CD40 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;CD40 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;CD40 GO:0032496| response to lipopolysaccharide CD40;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;CD40 GO:0006954| inflammatory response CD40;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CD40 GO:0006955| immune response CD40;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;CD40 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CD40;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;CD40 38827:[DB00480 DB07122] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07122|1-[4-(2-oxo-2-phenylethyl)phenyl]guanidine PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLAU GO:0010469| regulation of receptor activity TNFSF11;PLAU 38828:[DB00480 DB03581] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03581|Glucose-6-Phosphate glmS;GPI;SLCO2A1 common genes common pathways GO:0010469| regulation of receptor activity GPI;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;GPI GO:0055085| transmembrane transport ABCB1;SLCO2A1 GO:0001525| angiogenesis PTGS2;GPI GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPI 38829:[DB00480 DB02745] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;SLC29A1 38830:[DB00480 DB04059] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04059|8-(Pyrimidin-2-Ylamino)Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0010469| regulation of receptor activity PLAU;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;PLAU 38831:[DB00480 DB11660] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11660|Latanoprostene Bunod PTGFR;SLCO2B1 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;PTGFR GO:0055085| transmembrane transport SLCO2B1;ABCB1 GO:0032496| response to lipopolysaccharide PTGFR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGFR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;PTGFR 38832:[DB00480 DB05017] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05017|YSIL6 TNF;IL6 common genes common pathways GO:0008285| negative regulation of cell proliferation IL6;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;TNF;IL6 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;TNF;PTGS2 GO:0006954| inflammatory response PTGS2;TNF;IL6 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;IL6;TNFSF11 GO:0006955| immune response IL6;TNFSF11;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;TNFSF11;IL6 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0007275| multicellular organismal development TNFSF11;TNF GO:0043065| positive regulation of apoptotic process TNF;PTGS2;IL6 GO:0045672| positive regulation of osteoclast differentiation TNF;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0010469| regulation of receptor activity IL6;TNFSF11;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0002548| monocyte chemotaxis IL6;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF;IL6 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL6 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0008284| positive regulation of cell proliferation IL6;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;TNFSF11;TNF GO:0043066| negative regulation of apoptotic process PTGS2;IL6 38833:[DB00480 DB03506] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03506|9-Deazaadenine APRT common genes common pathways 38834:[DB00480 DB03455] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03455|(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid IL2 common genes common pathways GO:0050728| negative regulation of inflammatory response IL2;CDH5 GO:0007155| cell adhesion CDH5;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;IL2 GO:0043066| negative regulation of apoptotic process IL2;PTGS2 GO:0010469| regulation of receptor activity IL2;TNFSF11 GO:0006955| immune response IL2;TNFSF11 38835:[DB00480 DB12119] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12119|Gevokizumab IL1B common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;IL1B GO:0010469| regulation of receptor activity TNFSF11;IL1B GO:0019221| cytokine-mediated signaling pathway IL1B;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;IL1B GO:0032496| response to lipopolysaccharide PTGS2;IL1B GO:0046330| positive regulation of JNK cascade TNFSF11;IL1B GO:0008285| negative regulation of cell proliferation CDH5;IL1B;PTGS2 GO:0007566| embryo implantation PTGS2;IL1B GO:0006955| immune response IL1B;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IL1B GO:0006954| inflammatory response PTGS2;IL1B GO:0071260| cellular response to mechanical stimulus IL1B;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production IL1B;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;IL1B GO:0031622| positive regulation of fever generation PTGS2;IL1B 38836:[DB00480 DB07617] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07617|N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2A6 38837:[DB00480 DB13751] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13751|Glycyrrhizic acid HSD11B1;TNF;CASP3;NFKB2;NFKB1;LPL;AKR1C4;AKR1C3;AKR1C2;ALB;ABCB11 common genes common pathways GO:0019371| cyclooxygenase pathway AKR1C3;PTGS2 GO:0010942| positive regulation of cell death AKR1C3;PTGS2 GO:0006954| inflammatory response NFKB2;TNF;PTGS2;NFKB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;NFKB1;TNF;NFKB2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0006955| immune response TNF;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0007275| multicellular organismal development TNFSF11;TNF GO:0071260| cellular response to mechanical stimulus NFKB1;PTGS2 GO:0006629| lipid metabolic process LPL;AKR1C2;HSD11B1;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNF;TNFSF11 GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;TNF;CASP3 GO:0006693| prostaglandin metabolic process PTGS2;AKR1C2;AKR1C3 GO:0014070| response to organic cyclic compound PTGS2;CASP3 GO:0051384| response to glucocorticoid stimulus CASP3;TNF;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;LPL GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0055114| oxidation-reduction process PTGS2;HSD11B1;AKR1C4;AKR1C2;AKR1C3 GO:0042493| response to drug LPL;ABCB1;CASP3;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;AKR1C2;AKR1C3;TNFSF11 GO:0050728| negative regulation of inflammatory response NFKB1;CDH5 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0032496| response to lipopolysaccharide NFKB2;PTGS2;CASP3 GO:0042127| regulation of cell proliferation TNF;PTGS2 GO:0034097| response to cytokine stimulus NFKB2;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;AKR1C2;AKR1C3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;NFKB2;NFKB1;TNFSF11 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process ALB;PTGS2;NFKB1;CASP3 GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0010033| response to organic substance CASP3;PTGS2;TNF GO:0009887| organ morphogenesis TNFSF11;TNF GO:0006810| transport ABCB1;ABCB11 GO:0007568| aging NFKB2;PTGS2 GO:0010469| regulation of receptor activity TNF;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;CASP3 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0098869| PTGS2;ALB 38838:[DB00480 DB03711] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03711|6-Hydroxy-6-Methyl-Heptan-3-One LCN9 common genes common pathways 38839:[DB00480 DB02587] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02587|Colforsin ADCY2;GNAS;ADCY5;CFTR;ABCB1 common genes ABCB1 common pathways GO:0045672| positive regulation of osteoclast differentiation TNFSF11;GNAS GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;GNAS;PTGS2 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport CFTR;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 38840:[DB00480 DB08049] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0042493| response to drug ABCB1;COMT;PTGS2 GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0007612| learning COMT;PTGS2 GO:0014070| response to organic cyclic compound COMT;PTGS2 38841:[DB00480 DB11198] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;PTGS2 38842:[DB00480 DB03040] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03040|Nitrilotriacetic Acid LTF common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;LTF GO:0001503| ossification LTF;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;LTF GO:0043066| negative regulation of apoptotic process PTGS2;LTF 38843:[DB00480 DB00545] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00545|Pyridostigmine ACHE;BCHE;ALB;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation CDH5;BCHE;PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0007155| cell adhesion CDH5;ACHE GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0098869| PTGS2;ALB 38844:[DB00480 DB06549] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06549|Labradimil BDKRB2 common genes common pathways GO:1902219| BDKRB2;PTGS2 GO:0006954| inflammatory response PTGS2;BDKRB2 38845:[DB00480 DB12474] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C19;PTGS2 38846:[DB00480 DB00910] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;VDR GO:0033280| response to vitamin D CYP24A1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007275| multicellular organismal development TNFSF11;VDR GO:0009887| organ morphogenesis TNFSF11;VDR GO:0046697| decidualization PTGS2;VDR GO:0055114| oxidation-reduction process CYP3A4;CYP24A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VDR 38847:[DB00480 DB02405] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02405|12-Bromododecanoic Acid PAEP common genes common pathways GO:0007275| multicellular organismal development PAEP;TNFSF11 38848:[DB00480 DB01711] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01711|2,3,4,5,6-Pentafluorobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 38849:[DB00480 DB07901] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07901|5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE METAP1 common genes common pathways 38850:[DB00480 DB01620] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01620|Pheniramine HRH1;NR1I3 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0007613| memory PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I3 38851:[DB00480 DB08952] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08952|Indenolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006629| lipid metabolic process PTGS2;CYP2D6 38852:[DB00480 DB03637] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03637|Guanidine-3-Propanol PRSS3 common genes common pathways 38853:[DB00480 DB09035] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09035|Nivolumab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PDCD1 GO:0043065| positive regulation of apoptotic process PDCD1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;PDCD1 38854:[DB00480 DB03028] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03028|1h-Benoximidazole-2-Carboxylic Acid CTSD common genes common pathways 38855:[DB00480 DB12159] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12159|Dupilumab IL4R common genes common pathways GO:0042127| regulation of cell proliferation IL4R;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL4R GO:0030728| ovulation PTGS2;IL4R GO:0006955| immune response IL4R;TNFSF11 38856:[DB00480 DB08770] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08770|4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol ADORA2A common genes common pathways GO:0050728| negative regulation of inflammatory response CDH5;ADORA2A GO:0042493| response to drug ABCB1;PTGS2;ADORA2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0006954| inflammatory response PTGS2;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;ADORA2A GO:0008285| negative regulation of cell proliferation PTGS2;ADORA2A;CDH5 38857:[DB00480 DB01107] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug ABCB1;GABRG3;PTGS2 GO:0006810| transport GABRG2;ABCB1;GABRB3;GABRA1;GABRA4;GABRA6;GABRB1;GABRD;GABRB2;GABRA3;GABRA5 38858:[DB00480 DB02900] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02900|alpha-D-mannose 6-phosphate IGF2R;M6PR common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;IGF2R 38859:[DB00480 DB07498] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07498|4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 38860:[DB00480 DB00424] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 38861:[DB00480 DB01946] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01946|3-[1-(3-Aminopropyl)-1h-Indol-3-Yl]-4-(1-Methyl-1h-Indol-3-Yl)-1h-Pyrrole-2,5-Dione PDPK1;DMPK common genes common pathways GO:0019722| calcium-mediated signaling PDPK1;TNFSF11 38862:[DB00480 DB09535] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09535|Octocrylene ESR1;ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 38863:[DB00480 DB04021] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04021|MF268 ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 38864:[DB00480 DB09045] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09045|Dulaglutide GLP1R common genes common pathways 38865:[DB00480 DB06307] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06307|Apoptone BCL2 common genes common pathways GO:0009887| organ morphogenesis TNFSF11;BCL2 GO:0055085| transmembrane transport ABCB1;BCL2 GO:0006979| response to oxidative stress BCL2;PTGS2 GO:0098609| CDH5;BCL2 GO:0071456| cellular response to hypoxia PTGS2;BCL2 GO:0042493| response to drug BCL2;ABCB1;PTGS2 GO:0043066| negative regulation of apoptotic process BCL2;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;BCL2 GO:0034097| response to cytokine stimulus BCL2;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BCL2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCL2 GO:0009314| response to radiation PTGS2;BCL2 GO:0001503| ossification TNFSF11;BCL2 38866:[DB00480 DB09105] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09105|Asfotase Alfa S1PR1 common genes common pathways GO:0001525| angiogenesis S1PR1;PTGS2 GO:0001955| blood vessel maturation CDH5;S1PR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;S1PR1 GO:0008284| positive regulation of cell proliferation PTGS2;S1PR1 GO:0007155| cell adhesion S1PR1;CDH5 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;S1PR1 38867:[DB00480 DB12130] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;ALK GO:0042127| regulation of cell proliferation ALK;PTGS2 GO:0055114| oxidation-reduction process CYP3A5;CYP2C8;CYP2C19;PTGS2;CYP2B6 38868:[DB00480 DB06325] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06325|Pegpleranib PDGFB common genes common pathways GO:0007275| multicellular organismal development TNFSF11;PDGFB GO:0038001| paracrine signaling TNFSF11;PDGFB GO:0043406| positive regulation of MAP kinase activity PDGFB;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;PDGFB GO:0002548| monocyte chemotaxis PDGFB;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PDGFB GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PDGFB GO:0008284| positive regulation of cell proliferation PTGS2;PDGFB 38869:[DB00480 DB07286] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07286|BMS-564929 AR common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AR 38870:[DB00480 DB04620] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04620|Cycloleucine GRIN1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 GO:0007612| learning PTGS2;GRIN1 GO:0043065| positive regulation of apoptotic process PTGS2;GRIN1 GO:0019233| sensory perception of pain GRIN1;PTGS2 GO:0055074| calcium ion homeostasis GRIN1;TNFSF11 GO:0007613| memory PTGS2;GRIN1 GO:0019722| calcium-mediated signaling GRIN1;TNFSF11 38871:[DB00480 DB07344] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07344|3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL MCAT common genes common pathways GO:0006631| fatty acid metabolic process PTGS2;MCAT GO:0006629| lipid metabolic process PTGS2;MCAT GO:0006633| fatty acid biosynthetic process PTGS2;MCAT 38872:[DB00480 DB06016] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction HRH1;HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2;HRH1 GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0008284| positive regulation of cell proliferation DRD3;HTR2A;HTR2B;HTR1A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0007612| learning PTGS2;DRD3 GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP3A4 GO:0042493| response to drug DRD2;HTR2A;HTR2B;PTGS2;ABCB1;DRD3 GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A;HTR2B 38873:[DB00480 DB03923] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03923|Feruloyl Coenzyme A COMTD1 common genes common pathways 38874:[DB00480 DB09289] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09289|Tianeptine GRIA1;OPRM1;HTR1A;DRD3;CYP3A4 common genes common pathways GO:0019233| sensory perception of pain PTGS2;OPRM1 GO:0009314| response to radiation PTGS2;OPRM1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0042493| response to drug PTGS2;DRD3;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0007612| learning DRD3;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD3 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;DRD3 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 38875:[DB00480 DB07394] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07394|AUROVERTIN B ATP5B common genes common pathways GO:0006629| lipid metabolic process PTGS2;ATP5B GO:0001525| angiogenesis PTGS2;ATP5B 38876:[DB00480 DB05192] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05192|MB07811 THRB common genes common pathways GO:0009887| organ morphogenesis TNFSF11;THRB GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TNFSF11 38877:[DB00480 DB09341] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09341|Dextrose, unspecified form HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1 common genes common pathways GO:0071456| cellular response to hypoxia SLC2A4;PTGS2 GO:0055085| transmembrane transport SLC2A10;ABCB1;SLC2A4;SLC2A6;SLC2A9;SLC2A1;SLC5A1;SLC2A2;SLC2A11;SLC2A12;SLC2A8;SLC2A7;SLC2A3 GO:0042908| xenobiotic transport ABCB1;SLC2A1 GO:0071260| cellular response to mechanical stimulus PTGS2;SLC2A1 GO:0050873| brown fat cell differentiation PTGS2;SLC2A4 38878:[DB00480 DB04519] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006629| lipid metabolic process PPARA;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC22A8;SLC22A6;SLC22A11 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 38879:[DB00480 DB03664] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03664|UP5 CMPK1 common genes common pathways 38880:[DB00480 DB08088] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08088|2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile AR common genes common pathways GO:0006810| transport AR;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 38881:[DB00480 DB01216] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;SRD5A2;AKR1D1;PTGS2;SRD5A1 GO:0030154| cell differentiation SRD5A2;SRD5A1;TNFSF11 GO:0014070| response to organic cyclic compound SRD5A1;SRD5A2;PTGS2 GO:0055114| oxidation-reduction process CYP3A5;SRD5A1;CYP3A7;PTGS2;AKR1D1;SRD5A2;CYP3A4 GO:0042493| response to drug ABCB1;SRD5A1;SRD5A2;PTGS2 GO:0032355| response to estradiol stimulus SRD5A1;PTGS2 GO:0010033| response to organic substance PTGS2;SRD5A2 38882:[DB00480 DB08740] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08740|CYCLOHEXYLMETHYL-2,3-DIHYDROXY-5-METHYL-HEXYLAMIDE CTSD common genes common pathways 38883:[DB00480 DB06730] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP3A7;CYP3A5;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0038001| paracrine signaling PGR;TNFSF11 38884:[DB00480 DB00191] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A3;PTGS2;CYP1A2 GO:0007613| memory PTGS2;SLC6A4 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0010033| response to organic substance CYP1A2;SLC6A4;PTGS2 GO:0007568| aging SLC6A3;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0032355| response to estradiol stimulus CYP1A2;SLC6A4;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0055114| oxidation-reduction process MAOB;PTGS2;MAOA;CYP1A2 GO:0042493| response to drug MAOB;SLC6A3;SLC6A2;PTGS2;CYP1A2;ABCB1;SLC6A4 GO:0032496| response to lipopolysaccharide PTGS2;MAOB;CYP1A2 38885:[DB00480 DB06650] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06650|Ofatumumab MS4A1 common genes common pathways 38886:[DB00480 DB00371] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0006810| transport GABRD;GABRA4;GABRA6;GABRB1;GABRB2;GABRA5;GABRA3;ABCB1;GABRG2;GABRA1;GABRB3 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2E1 GO:0042493| response to drug CYP2E1;PTGS2;GABRG3;ABCB1 38887:[DB00480 DB03456] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03456|N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 38888:[DB00480 DB06684] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0007613| memory PTGS2;SLC6A4 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0042493| response to drug SLC6A4;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2C18;PTGS2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 38889:[DB00480 DB04409] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04409|Naphthalene Trisulfonate FGF1 common genes common pathways GO:0043406| positive regulation of MAP kinase activity FGF1;TNFSF11 GO:0034605| cellular response to heat FGF1;PTGS2 GO:0010469| regulation of receptor activity FGF1;TNFSF11 GO:1902533| TNFSF11;FGF1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGF1 GO:0008284| positive regulation of cell proliferation PTGS2;FGF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;FGF1 GO:0030154| cell differentiation TNFSF11;FGF1 GO:0007275| multicellular organismal development TNFSF11;FGF1 GO:0001525| angiogenesis PTGS2;FGF1 38890:[DB00480 DB02509] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02509|Farnesol MAOB;NR1H4;MAOB common genes common pathways GO:0007043| cell-cell junction assembly CDH5;NR1H4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;NR1H4 GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0050728| negative regulation of inflammatory response NR1H4;CDH5 GO:0042493| response to drug ABCB1;PTGS2;MAOB GO:0055114| oxidation-reduction process PTGS2;MAOB GO:0006954| inflammatory response NR1H4;PTGS2 38891:[DB00480 DB08560] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08560|3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE PPARG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0010033| response to organic substance PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 38892:[DB00480 DB07917] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07917|4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE HPGDS common genes common pathways GO:0006631| fatty acid metabolic process HPGDS;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0001516| prostaglandin biosynthetic process HPGDS;PTGS2 GO:0006629| lipid metabolic process HPGDS;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;HPGDS GO:0019371| cyclooxygenase pathway HPGDS;PTGS2 38893:[DB00480 DB03384] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03384|Fica CASP7 common genes common pathways 38894:[DB00480 DB07630] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07630|N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 38895:[DB00480 DB00283] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00283|Clemastine HRH1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 38896:[DB00480 DB00931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00931|Metacycline ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| PTGS2;ALB 38897:[DB00480 DB05233] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05233|AP1081 ESR1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1 38898:[DB00480 DB07789] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle PLK1;ABCB1 GO:0016567| protein ubiquitination CRBN;PLK1 GO:0043066| negative regulation of apoptotic process PTGS2;PLK1 38899:[DB00480 DB06945] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06945|N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide ADAMTS5 common genes common pathways 38900:[DB00480 DB02855] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02855|N-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline CTSB common genes common pathways GO:0046697| decidualization CTSB;PTGS2 38901:[DB00480 DB00856] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00856|Chlorphenesin CYP2B;CYP19A1;CYP3A4;XDH;PTGS2;BCHE common genes PTGS2 common pathways GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP19A1;PTGS2;XDH GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0006954| inflammatory response PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38902:[DB00480 DB02328] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02328|2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid CTH common genes common pathways GO:0043066| negative regulation of apoptotic process CTH;PTGS2 GO:1990830| TNFSF11;CTH GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CTH GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CTH 38903:[DB00480 DB04491] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04491|Diisopropylphosphono Group CFB;DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 38904:[DB00480 DB01089] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01089|Deserpidine SLC18A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC18A2 38905:[DB00480 DB13166] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13166|Zofenopril ACE common genes common pathways GO:0008217| regulation of blood pressure ACE;PTGS2 38906:[DB00480 DB01223] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2;HDAC2 GO:0043066| negative regulation of apoptotic process ADORA1;PDE3A;HDAC2;PTGS2 GO:0008284| positive regulation of cell proliferation HDAC2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;TNFSF11 GO:0055114| oxidation-reduction process CYP1A2;CYP3A4;CYP2E1;CYP2C19;PTGS2 GO:0042493| response to drug PTGS2;HDAC2;PDE3A;CYP2E1;ABCB1;CYP1A2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0050728| negative regulation of inflammatory response ADORA1;CDH5 GO:0097756| ADORA1;PTGS2 GO:0034605| cellular response to heat PTGS2;HDAC2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;PDE3A;CYP3A4;CYP1A2 GO:0006954| inflammatory response ADORA3;PTGS2;ADORA1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0008285| negative regulation of cell proliferation ADORA1;CDH5;PTGS2;ADORA3 38907:[DB00480 DB09236] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways GO:0055085| transmembrane transport CACNA1D;CACNA1C;CACNA1S;ABCB1;CACNA1F GO:0098869| PTGS2;ALB GO:0006810| transport ABCB1;CACNB1;CACNB3;CACNB4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0006954| inflammatory response PTGS2;ORM1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38908:[DB00480 DB08930] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes ABCB1 common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0006855| drug transmembrane transport ABCG2;SLC22A2;ABCB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0042493| response to drug ABCG2;UGT1A1;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP3A43;CYP3A4;CYP3A5;CYP3A7;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:1901529| ABCB1 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A2;SLC22A8;ABCG2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006810| transport ABCG2;ABCB1 38909:[DB00480 DB11858] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways GO:0010942| positive regulation of cell death PTGS2;CYSLTR2 GO:0006955| immune response TNFSF11;CYSLTR2 38910:[DB00480 DB14132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;ADORA2A GO:0042493| response to drug CYP1A2;ABCB1;ADORA2A;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADORA2A GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006954| inflammatory response PTGS2;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;ADORA2A GO:0006629| lipid metabolic process CYP1A2;PTGS2 38911:[DB00480 DB07257] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07257|4-(2-chlorophenyl)-8-(2-hydroxyethyl)-6-methylpyrrolo[3,4-e]indole-1,3(2H,6H)-dione WEE1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle WEE1;ABCB1 38912:[DB00480 DB07716] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07716|(4Z)-2,8:7,12:11,15:14,18:17,22-PENTAANHYDRO-4,5,6,9,10,13,19,20,21-NONADEOXY-D-ARABINO-D-ALLO-D-ALLO-DOCOSA-4,9,20-TRIENITOL IGKC common genes common pathways GO:0006955| immune response IGKC;TNFSF11 38913:[DB00480 DB09479] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09479|Rubidium Rb-82 FXYD2;ATP1A1;ATP1B1;ATP1B2;ATP1B3;ATP1A4;ATP1A2;ATP1A3 common genes common pathways GO:0007613| memory ATP1A3;PTGS2 GO:0008217| regulation of blood pressure ATP1A2;PTGS2;ATP1A1 GO:0071260| cellular response to mechanical stimulus ATP1A2;ATP1A1;PTGS2 GO:0006810| transport ATP1B3;FXYD2;ABCB1;ATP1B2 GO:0042127| regulation of cell proliferation FXYD2;PTGS2 GO:0007155| cell adhesion ATP1B2;ATP1B1;CDH5 GO:0042493| response to drug ABCB1;ATP1A1;PTGS2;ATP1A3 38914:[DB00480 DB02462] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02462|Thiocoumarin NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 38915:[DB00480 DB04509] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04509|N-Methylnaloxonium CES1;CES1 common genes common pathways 38916:[DB00480 DB02395] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02395|3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol NQO1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;PTGS2 GO:0006979| response to oxidative stress NQO1;PTGS2 GO:0007568| aging NQO1;PTGS2 GO:0032355| response to estradiol stimulus NQO1;PTGS2 GO:0014070| response to organic cyclic compound NQO1;PTGS2 38917:[DB00480 DB00964] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00964|Apraclonidine ADRA2A;ADRA1A;ADRA2B common genes common pathways GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug ADRA1A;PTGS2;ABCB1 GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0007568| aging ADRA1A;PTGS2 38918:[DB00480 DB00487] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A 38919:[DB00480 DB07154] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07154|(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion CDH5;DPP4 38920:[DB00480 DB13881] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13881|Tisagenlecleucel CD19 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD19;TNFSF11 38921:[DB00480 DB04233] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04233|(Hydroxyethyloxy)Tri(Ethyloxy)Octane CLPS;PNLIP;RHO common genes common pathways GO:0006629| lipid metabolic process PNLIP;PTGS2;CLPS 38922:[DB00480 DB03703] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03703|Cyclohexanol ADH1B common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1B 38923:[DB00480 DB09203] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09203|Synephrine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;ADRA1D GO:0042493| response to drug ADRA1A;PTGS2;ABCB1 GO:0007568| aging PTGS2;ADRA1A GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0045907| positive regulation of vasoconstriction ADRA1D;ADRA1B;PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;PTGS2;ADRA1B;ADRA1A 38924:[DB00480 DB13132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13132|Artemisinin CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2B6 38925:[DB00480 DB04852] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04852|Implitapide MTTP common genes common pathways GO:0006629| lipid metabolic process PTGS2;MTTP 38926:[DB00480 DB05920] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05920|RTA 744 TOP2A common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A 38927:[DB00480 DB08163] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08163|5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine AMD1 common genes common pathways 38928:[DB00480 DB03894] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03894|N-Propargyl-1(S)-Aminoindan MAOB;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0042493| response to drug PTGS2;MAOB;ABCB1 GO:0055114| oxidation-reduction process PTGS2;MAOB 38929:[DB00480 DB05938] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05938|Edonerpic APP common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0007613| memory APP;PTGS2 GO:0008285| negative regulation of cell proliferation APP;CDH5;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;TNFSF11 GO:0007155| cell adhesion APP;CDH5 GO:0007612| learning APP;PTGS2 GO:0046330| positive regulation of JNK cascade APP;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade APP;TNFSF11 GO:0051260| protein homooligomerization APP;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;APP GO:0006979| response to oxidative stress PTGS2;APP 38930:[DB00480 DB12610] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12610|Ebselen EPHX2 common genes common pathways GO:0008217| regulation of blood pressure EPHX2;PTGS2 GO:0006954| inflammatory response EPHX2;PTGS2 GO:0006629| lipid metabolic process EPHX2;PTGS2 38931:[DB00480 DB07063] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07063|{3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 38932:[DB00480 DB11397] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0098869| ALB;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;BCHE GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0007612| learning PTGS2;BCHE 38933:[DB00480 DB00600] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00600|Monobenzone TYR common genes common pathways GO:0033280| response to vitamin D PTGS2;TYR GO:0055114| oxidation-reduction process TYR;PTGS2 38934:[DB00480 DB03889] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03889|S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione HAGH common genes common pathways 38935:[DB00480 DB01831] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01831|Tryptophanyl-5'amp WARS;trpS common genes common pathways GO:0001525| angiogenesis WARS;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;WARS;PTGS2 38936:[DB00480 DB01589] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0006810| transport GABRB3;GABRA1;ABCB1;GABRG2;GABRB2;GABRA5;GABRA3;GABRD;GABRR2;GABRR1;GABRA6;GABRA4;GABRB1 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP3A4;CYP2B6;CYP2C9 GO:0042493| response to drug GABRG3;ABCB1;PTGS2 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS2 38937:[DB00480 DB02637] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02637|Oxaloacetate Ion CS;mdh;SPR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;SPR 38938:[DB00480 DB08435] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08435|(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid PPARG common genes common pathways GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG 38939:[DB00480 DB07580] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07580|BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE APCS common genes common pathways 38940:[DB00480 DB00104] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;SSTR1;SSTR2;SSTR5;CDH5 GO:0055114| oxidation-reduction process MPO;PTGS2;CYP3A4 GO:0043066| negative regulation of apoptotic process MPO;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;MPO GO:1990830| TNFSF11;SSTR1 GO:0006979| response to oxidative stress PTGS2;MPO GO:0007568| aging MPO;PTGS2 38941:[DB00480 DB06410] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06410|Doxercalciferol VDR;CYP27A1 common genes common pathways GO:0007275| multicellular organismal development VDR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VDR GO:0055114| oxidation-reduction process CYP27A1;PTGS2 GO:0046697| decidualization VDR;PTGS2 GO:0009887| organ morphogenesis VDR;TNFSF11 38942:[DB00480 DB01064] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade PIK3R1;TNFSF11;PIK3R2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;SOD1;CYP1A1 GO:0042493| response to drug SOD1;CYP1A1;PTGS2;ABCB1 GO:0043066| negative regulation of apoptotic process PIK3R1;PTGS2;SOD1 GO:0008284| positive regulation of cell proliferation MAPK1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PIK3R2;ADRB2;TNFSF11;PIK3R1 GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2;MAPK1 GO:0010033| response to organic substance PTGS2;SOD1;CYP1A1 GO:0009887| organ morphogenesis TNFSF11;MAPK1 GO:0006979| response to oxidative stress PTGS2;SOD1 GO:0007568| aging SOD1;CYP1A1;ADRB3;PTGS2 GO:0033598| mammary gland epithelial cell proliferation MAPK1;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAPK1 GO:0043065| positive regulation of apoptotic process SOD1;PTGS2 GO:0019233| sensory perception of pain PTGS2;MAPK1 GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2;ADRB3 GO:0008217| regulation of blood pressure SOD1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0034644| cellular response to UV PTGS2;PIK3R1 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0007566| embryo implantation SOD1;PTGS2 38943:[DB00480 DB03948] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03948|6-Chloropurine Riboside, 5'-Monophosphate IMPDH1;IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process IMPDH1;PTGS2;IMPDH2 38944:[DB00480 DB06721] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06721|Gimatecan SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;ABCB1 38945:[DB00480 DB04853] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04853|Binodenoson ADORA2A common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;ADORA2A GO:0006954| inflammatory response ADORA2A;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0042493| response to drug ADORA2A;PTGS2;ABCB1 GO:0050728| negative regulation of inflammatory response CDH5;ADORA2A 38946:[DB00480 DB01947] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01947|RU78262 SRC common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| SRC;CDH5 GO:1902533| SRC;TNFSF11 GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug ABCB1;PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC 38947:[DB00480 DB02515] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02515|3-Phosphoglycerol PFKFB1;ALDOB;pdxJ common genes common pathways GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 38948:[DB00480 DB03486] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03486|Phosphomethylphosphonic Acid Guanosyl Ester CANT1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CANT1;TNFSF11 38949:[DB00480 DB07747] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07747|(3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 38950:[DB00480 DB01678] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01678|RU84687 SRC common genes common pathways GO:0070542| response to fatty acid SRC;PTGS2 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0045453| bone resorption SRC;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:1902533| TNFSF11;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug ABCB1;PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process SRC;PTGS2 38951:[DB00480 DB10772] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB10772|Foreskin keratinocyte (neonatal) FGF1;EGFR;CSF2RA;IL1B;IL6;IFNG;FGFR2;PDGFRA;TGFBR2;TGFB1;TNF;VEGFA common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway TGFB1;CDH5;TGFBR2 GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0010033| response to organic substance TGFB1;TGFBR2;PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNF;VEGFA;EGFR;TGFB1;FGF1;TNFSF11 GO:0009887| organ morphogenesis FGFR2;TNFSF11;TGFBR2;TNF GO:0030282| bone mineralization FGFR2;PTGS2 GO:0007568| aging TGFB1;PTGS2;TGFBR2 GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0034605| cellular response to heat PTGS2;FGF1 GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0098609| CDH5;EGFR GO:0010469| regulation of receptor activity IFNG;VEGFA;TNF;TNFSF11;FGF1;TGFB1;IL6;IL1B GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2;TGFB1 GO:1902533| TNFSF11;FGF1 GO:0045429| positive regulation of nitric oxide biosynthetic process IFNG;EGFR;PTGS2;TNF;IL1B GO:0006979| response to oxidative stress PTGS2;EGFR GO:0002548| monocyte chemotaxis TNFSF11;IL6 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0042493| response to drug TGFB1;ABCB1;PTGS2;TGFBR2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;EGFR;PDGFRA;TGFB1;FGFR2;TNFSF11;FGF1 GO:0019221| cytokine-mediated signaling pathway CSF2RA;TNFSF11;IL1B;IL6 GO:0048661| positive regulation of smooth muscle cell proliferation IL6;FGFR2;TNF;PTGS2;TGFBR2;EGFR GO:0046330| positive regulation of JNK cascade TNFSF11;IL1B;TNF GO:0032496| response to lipopolysaccharide PTGS2;FGFR2;IL1B GO:0042127| regulation of cell proliferation TNF;PTGS2;TGFBR2;EGFR;TGFB1 GO:0060749| mammary gland alveolus development VEGFA;TNFSF11 GO:0045786| negative regulation of cell cycle TGFB1;PTGS2 GO:0043066| negative regulation of apoptotic process VEGFA;EGFR;PTGS2;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;EGFR;VEGFA;IL6;IL1B;TGFB1;FGFR2;TNFSF11;FGF1 GO:0008284| positive regulation of cell proliferation FGF1;IL6;IL1B;FGFR2;TGFB1;EGFR;PDGFRA;IFNG;VEGFA;PTGS2;TGFBR2 GO:0014070| response to organic cyclic compound TGFBR2;PTGS2;EGFR;TGFB1 GO:0033280| response to vitamin D TGFB1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;TGFB1;IL1B;IL6;TGFBR2;PTGS2 GO:0030154| cell differentiation TNFSF11;FGF1;VEGFA;TGFBR2 GO:0007566| embryo implantation TGFBR2;PTGS2;IL1B GO:0051384| response to glucocorticoid stimulus IL6;TNF;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;TGFB1;EGFR;VEGFA;TNF;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA GO:0006955| immune response TNFSF11;IL1B;IL6;IFNG;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;IL1B;IL6;TNF GO:0006954| inflammatory response IL6;IL1B;TGFB1;TNF;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity IL6;IL1B;TGFB1;TNFSF11;TNF GO:0007275| multicellular organismal development TNF;PDGFRA;EGFR;VEGFA;FGF1;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;IL1B;TNFSF11 GO:0031622| positive regulation of fever generation IL1B;TNF;PTGS2 GO:0001525| angiogenesis PTGS2;VEGFA;FGFR2;FGF1 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;TGFB1;IL1B GO:0071260| cellular response to mechanical stimulus IL1B;TGFB1;PTGS2;EGFR GO:0001503| ossification EGFR;TNFSF11 GO:0042327| positive regulation of phosphorylation VEGFA;EGFR;TNFSF11 GO:0009314| response to radiation PTGS2;TGFB1 GO:0042307| positive regulation of protein import into nucleus TGFB1;PTGS2 GO:0043065| positive regulation of apoptotic process TGFB1;IL6;PTGS2;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;IFNG;TNF 38952:[DB00480 DB02107] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02107|Leucine - Reduced Carbonyl SPINK6 common genes common pathways 38953:[DB00480 DB08488] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08488|4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 38954:[DB00480 DB07087] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07087|4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL ESR1;NCOA2 common genes common pathways GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11;NCOA2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 38955:[DB00480 DB04256] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04256|4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid GRM1 common genes common pathways GO:0019233| sensory perception of pain GRM1;PTGS2 38956:[DB00480 DB06538] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06538|Robalzotan HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A 38957:[DB00480 DB08156] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08156|3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID CA1;CA2 common genes common pathways GO:0045780| positive regulation of bone resorption TNFSF11;CA2 GO:0010033| response to organic substance CA2;PTGS2 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 38958:[DB00480 DB14002] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14002|D-alpha-Tocopherol acetate SEC14L4;SEC14L3;SEC14L2;NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0010033| response to organic substance SOD1;PTGS2;PPP2CA GO:0034605| cellular response to heat PTGS2;HMOX1 GO:0032355| response to estradiol stimulus GSTP1;PTGS2;NQO1 GO:0045780| positive regulation of bone resorption PRKCA;TNFSF11 GO:0006810| transport TTPA;ABCB1 GO:0007568| aging PTGS2;SOD1;NQO1;GCLC GO:0071456| cellular response to hypoxia PTGS2;HMOX1 GO:0006979| response to oxidative stress HMOX1;SOD1;PTGS2;NQO1;GCLC GO:0098869| PTGS2;GSTP1;GSTO1 GO:0051260| protein homooligomerization HMOX1;TNFSF11 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process PPP2CB;CRBN GO:0042493| response to drug PTGS2;SOD1;ABCB1 GO:0055114| oxidation-reduction process GSTO1;NQO1;SOD1;HMOX1;ALOX5;PTGS2 GO:0019372| lipoxygenase pathway ALOX5;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2 GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0043066| negative regulation of apoptotic process SOD1;GSTP1;PTGS2;GCLC;NQO1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TNFSF11 GO:0007155| cell adhesion PRKCA;CDH5 GO:0014070| response to organic cyclic compound NQO1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;HMOX1;SOD1 GO:0008285| negative regulation of cell proliferation CDH5;HMOX1;PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0006954| inflammatory response PTGS2;ALOX5 GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCB;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;TNFSF11;PRKCB GO:0001525| angiogenesis HMOX1;PTGS2;PRKCA GO:0043065| positive regulation of apoptotic process SOD1;HMOX1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;GCLC GO:0006629| lipid metabolic process TTPA;PTGS2 38959:[DB00480 DB08190] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NQO2 38960:[DB00480 DB08221] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08221|N-{4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]PHENYL}-3-(TRIFLUOROMETHYL)BENZAMIDE TEK common genes common pathways GO:0010033| response to organic substance PTGS2;TEK GO:1902533| TEK;TNFSF11 GO:0050728| negative regulation of inflammatory response CDH5;TEK GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TEK GO:0043066| negative regulation of apoptotic process TEK;PTGS2 GO:0001525| angiogenesis TEK;PTGS2 38961:[DB00480 DB04578] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04578|(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 38962:[DB00480 DB01349] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;AGTR1 GO:0008217| regulation of blood pressure AGTR2;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006954| inflammatory response AGTR2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process AGTR2;PTGS2 GO:0042127| regulation of cell proliferation AGTR1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;AGTR2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0010243| response to organic nitrogen PTGS2;AGTR2 38963:[DB00480 DB11774] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11774|Pazufloxacin CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 38964:[DB00480 DB04910] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04910|Oxibendazole TUBB4B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4B 38965:[DB00480 DB08772] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08772|3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID AKR1B10;AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B10;AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0010033| response to organic substance AKR1B1;PTGS2 38966:[DB00480 DB00471] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport SLCO2B1;ABCB1 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0019372| lipoxygenase pathway ALOX5;PTGS2 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;ALOX5;PTGS1;CYP3A4;CYP2A6;CYP2C9 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0006954| inflammatory response ALOX5;PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1;CYP3A4;CYP2C9 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 38967:[DB00480 DB08222] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08222|METHOXYUNDECYLPHOSPHINIC ACID CLPS;PNLIP common genes common pathways GO:0006629| lipid metabolic process PNLIP;PTGS2;CLPS 38968:[DB00480 DB13500] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13500|Otilonium CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 38969:[DB00480 DB02131] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02131|N-1-Methylheptylformamide ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;PTGS2 38970:[DB00480 DB01951] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01951|Gpi-1046 FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CDH5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TNFSF11 38971:[DB00480 DB00140] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00140|Riboflavin RFK;BLVRB;MAOA;MTHFR;SLC22A6 common genes common pathways GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0042493| response to drug PTGS2;MTHFR;ABCB1 GO:0055114| oxidation-reduction process PTGS2;MAOA;BLVRB;MTHFR 38972:[DB00480 DB01231] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 38973:[DB00480 DB00144] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00144|Phosphatidyl serine DGKG;DGKD;PTDSS2;SMPD4;SMPD3;ATP8A1;PRKCA;PTDSS1;PISD;SCARB1 common genes common pathways GO:0001525| angiogenesis PTGS2;PRKCA GO:0007275| multicellular organismal development TNFSF11;DGKD;SMPD3 GO:0006629| lipid metabolic process PISD;PTDSS2;PTDSS1;PTGS2;SMPD3 GO:0045332| phospholipid translocation ABCB1;ATP8A1 GO:0007612| learning PTGS2;ATP8A1 GO:0007155| cell adhesion CDH5;PRKCA GO:0045780| positive regulation of bone resorption TNFSF11;PRKCA GO:0051260| protein homooligomerization TNFSF11;DGKD GO:0010033| response to organic substance DGKD;PTGS2 38974:[DB00480 DB00917] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGER4;PTGER2;PTGER1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGER2 GO:0050728| negative regulation of inflammatory response PTGER4;CDH5 GO:0010243| response to organic nitrogen ABCC4;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;ABCC4 GO:0042493| response to drug PTGS2;ABCC4;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP19A1;CYP11A1;ABCC4 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0006810| transport ABCB1;ABCC5 GO:0010033| response to organic substance ABCC4;PTGS2 GO:0055085| transmembrane transport SLCO2A1;SLC51B;SLCO3A1;SLCO1A2;SLC22A11;SLC22A6;SLC22A2;SLCO2B1;SLC22A8;SLCO1B1;SLCO4A1;SLC22A7;SLC51A;SLCO1C1;ABCC5;ABCB1;ABCC4 GO:0071260| cellular response to mechanical stimulus PTGS2;PTGER4 GO:0006629| lipid metabolic process CYP11A1;PTGS2 GO:0031622| positive regulation of fever generation PTGER3;PTGS2 GO:0070371| ERK1 and ERK2 cascade PTGER4;TNFSF11 GO:0006955| immune response PTGER4;PTGDR2;TNFSF11 GO:0019722| calcium-mediated signaling TNFSF11;PTGDR2 GO:0014070| response to organic cyclic compound PTGS2;ABCC4 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 38975:[DB00480 DB03963] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03963|S-(Dimethylarsenic)Cysteine TLR2;NOS3;COPG1;XRCC4;msrA common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS3 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0007612| learning PTGS2;TLR2 GO:0032496| response to lipopolysaccharide TLR2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TLR2 GO:0008285| negative regulation of cell proliferation TLR2;PTGS2;NOS3;CDH5 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0070542| response to fatty acid TLR2;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TLR2 GO:0006954| inflammatory response PTGS2;TLR2 GO:0006955| immune response TLR2;TNFSF11 GO:0001525| angiogenesis PTGS2;NOS3 38976:[DB00480 DB08353] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08353|2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 38977:[DB00480 DB03292] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03292|3-Phosphono-D-alanine PSPH common genes common pathways 38978:[DB00480 DB07700] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0006693| prostaglandin metabolic process AKR1C3;PTGS2 GO:0010942| positive regulation of cell death AKR1C3;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;AKR1C3 GO:0008284| positive regulation of cell proliferation PTGS2;AKR1C3 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;AKR1C3 38979:[DB00480 DB01271] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01271|Idursulfase PLIN3 common genes common pathways 38980:[DB00480 DB09342] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09342|Propoxycaine CES1 common genes common pathways 38981:[DB00480 DB07680] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07680|[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID CMA1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;CMA1 38982:[DB00480 DB09230] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006810| transport ABCB1;CACNB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38983:[DB00480 DB00850] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0007613| memory PTGS2;DRD1 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0055085| transmembrane transport ABCB1;CALM1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;DRD1;DRD2;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2D6;CYP2C9;CYP2B6;CYP2C18;PTGS2;CYP2C19;CYP2C8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0007612| learning PTGS2;DRD1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 38984:[DB00480 DB04957] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0055085| transmembrane transport ABCB1;KCNH2;KCNQ1 GO:0007568| aging CYP1A1;PTGS2 GO:0042493| response to drug ABCB1;CYP1A1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP3A5;CYP1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 38985:[DB00480 DB04919] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04919|Alfimeprase FGA;FGB common genes common pathways GO:0045907| positive regulation of vasoconstriction FGB;PTGS2;FGA 38986:[DB00480 DB01595] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01595|Nitrazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;SCN1A;CYP3A4;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006810| transport GABRR2;GABRD;GABRB1;GABRA6;GABRR1;GABRA4;GABRA5;GABRA3;GABRB2;ABCB1;GABRG2;GABRA1;GABRB3 GO:0055085| transmembrane transport SCN1A;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2E1;PTGS2 GO:0042493| response to drug ABCB1;GABRG3;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 38987:[DB00480 DB13203] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13203|Bamifylline CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 38988:[DB00480 DB06479] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 38989:[DB00480 DB08885] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08885|Aflibercept VEGFA;PGF;VEGFB common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;VEGFA;PGF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VEGFA GO:0043066| negative regulation of apoptotic process VEGFA;PTGS2;VEGFB GO:0060749| mammary gland alveolus development VEGFA;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade VEGFB;TNFSF11 GO:0042493| response to drug VEGFB;ABCB1;PTGS2;PGF GO:0010469| regulation of receptor activity VEGFB;TNFSF11;PGF;VEGFA GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0043406| positive regulation of MAP kinase activity VEGFA;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;VEGFA GO:0001525| angiogenesis PTGS2;PGF;VEGFA;VEGFB GO:0007275| multicellular organismal development VEGFA;PGF;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis VEGFA;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA GO:0030154| cell differentiation TNFSF11;PGF;VEGFA 38990:[DB00480 DB03832] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03832|3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium CROT common genes common pathways GO:0006629| lipid metabolic process CROT;PTGS2 GO:0006631| fatty acid metabolic process CROT;PTGS2 38991:[DB00480 DB02353] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02353|Heparin Disaccharide Iii-S CCL5 common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;CCL5 GO:0034612| response to tumor necrosis factor PTGS2;CCL5 GO:0034097| response to cytokine stimulus CCL5;PTGS2 GO:0034112| positive regulation of homotypic cell-cell adhesion CCL5;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;CCL5 GO:0002548| monocyte chemotaxis TNFSF11;CCL5 GO:0042327| positive regulation of phosphorylation TNFSF11;CCL5 GO:0006954| inflammatory response CCL5;PTGS2 GO:0006955| immune response TNFSF11;CCL5 38992:[DB00480 DB11760] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;ABCG2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 38993:[DB00480 DB08750] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08750|1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 38994:[DB00480 DB01456] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01456|5-androstenedione CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 38995:[DB00480 DB02691] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B1;SLCO1A2;SLCO1B3;ABCB1 GO:0008285| negative regulation of cell proliferation FABP6;CDH5;PTGS2 GO:0006629| lipid metabolic process FABP6;PTGS2 38996:[DB00480 DB01889] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01889|16,17-Androstene-3-Ol NR1I3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;TNFSF11 38997:[DB00480 DB00614] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00614|Furazolidone MAOB;MAOA common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0055114| oxidation-reduction process MAOA;PTGS2;MAOB GO:0042493| response to drug ABCB1;PTGS2;MAOB 38998:[DB00480 DB01733] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01733|L-Phospholactate PKM common genes common pathways GO:0010033| response to organic substance PTGS2;PKM 38999:[DB00480 DB05514] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05514|Cobiprostone CLCN2 common genes common pathways GO:0055085| transmembrane transport ABCB1;CLCN2 GO:0006810| transport CLCN2;ABCB1 39000:[DB00480 DB07831] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07831|2-{[(6-OXO-1,6-DIHYDROPYRIDIN-3-YL)METHYL]AMINO}-N-[4-PROPYL-3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE ABL1 common genes common pathways GO:0007155| cell adhesion CDH5;ABL1 GO:0042127| regulation of cell proliferation PTGS2;ABL1 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ABL1 39001:[DB00480 DB07093] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07093|{3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0010033| response to organic substance PTGS2;AKR1B1 39002:[DB00480 DB01559] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP2C18;CYP2B6;CYP3A4 GO:0006810| transport ABCB1;GABRG2;GABRA1;GABRB3;GABRD;GABRR2;GABRR1;GABRB1;GABRB2;GABRA3;GABRA5 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39003:[DB00480 DB01272] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01272|Alglucosidase alfa M6PR common genes common pathways 39004:[DB00480 DB04794] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP3A4;CYP2B6;CYP19A1 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 39005:[DB00480 DB07446] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07446|N-(biphenyl-4-ylsulfonyl)-D-leucine MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 39006:[DB00480 DB12141] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0007613| memory PTGS2;HTR2A GO:0030154| cell differentiation TNFSF11;FLT3;AXL GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0006855| drug transmembrane transport ABCB1;SLC22A1;SLC47A1;ABCG2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006954| inflammatory response PTGS2;AXL GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity ALK;TNFSF11 GO:0006810| transport ABCB1;ABCG2 GO:0007568| aging PTGS2;HTR2A GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0098869| PTGS2;ALB GO:0055085| transmembrane transport ABCG2;ABCB1;SLC22A1;SLC47A1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0043406| positive regulation of MAP kinase activity HTR2B;HTR2A;FLT3;TNFSF11 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation ALK;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR2B;HTR1A;PTGS2;FLT3 GO:0043066| negative regulation of apoptotic process PTGS2;AXL;HTR2B;ALB GO:0042493| response to drug ABCB1;HTR1B;HTR2C;PTGS2;ABCG2;HTR2B;HTR2A GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0010243| response to organic nitrogen FLT3;PTGS2 GO:0019221| cytokine-mediated signaling pathway FLT3;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade AXL;TNFSF11 39007:[DB00480 DB00769] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 39008:[DB00480 DB07396] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07396|1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid PYGL common genes common pathways 39009:[DB00480 DB05796] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05796|Daglutril MME common genes common pathways GO:0019233| sensory perception of pain MME;PTGS2 39010:[DB00480 DB09140] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0007568| aging MT-CO1;PTGS2 GO:0098869| HBB;HBA1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;PTGS2 GO:0006979| response to oxidative stress MT-CO1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;MT-CO1;NOX1 GO:0048661| positive regulation of smooth muscle cell proliferation NOX1;PTGS2 GO:0046330| positive regulation of JNK cascade NOX1;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;NOX1 GO:0008217| regulation of blood pressure HBB;NOX1;PTGS2 GO:0006954| inflammatory response NOX1;PTGS2 GO:0010942| positive regulation of cell death HBA1;PTGS2;HBB GO:0010575| positive regulation vascular endothelial growth factor production NOX1;PTGS2 GO:0001525| angiogenesis PTGS2;NOX1 39011:[DB00480 DB04946] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP3A7;CYP2E1;CYP3A5;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1;HTR2A;DRD1;DRD2;ADRA1A;DRD3;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;PTGS2;DRD3 GO:0007612| learning PTGS2;DRD1;DRD3 GO:0008285| negative regulation of cell proliferation ADRA1A;DRD2;PTGS2;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A;HTR2A;ADRA2C;HRH1 GO:0007613| memory HRH1;HTR2A;DRD1;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A 39012:[DB00480 DB01237] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01237|Bromodiphenhydramine HRH1;SLC22A6 common genes common pathways GO:0007613| memory PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0055085| transmembrane transport ABCB1;SLC22A6 39013:[DB00480 DB11614] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;PTAFR GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;CYP3A4;CYP2C19;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PTAFR GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;PTAFR;HRH1 GO:0045987| positive regulation of smooth muscle contraction PTAFR;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1;PTAFR GO:0006955| immune response TNFSF11;PTAFR 39014:[DB00480 DB08259] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08259|7-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}HEPTANOIC ACID EPHX2 common genes common pathways GO:0006954| inflammatory response EPHX2;PTGS2 GO:0006629| lipid metabolic process EPHX2;PTGS2 GO:0008217| regulation of blood pressure PTGS2;EPHX2 39015:[DB00480 DB01738] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01738|Phosphorylcolamine PRKCB common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;PRKCB GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;PRKCB 39016:[DB00480 DB03978] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03978|Tyrosinal tyrS;YARS;YARS common genes common pathways 39017:[DB00480 DB06814] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06814|Protokylol ADRB2 common genes common pathways GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 39018:[DB00480 DB07919] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOA 39019:[DB00480 DB03945] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03945|N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium CRP;ELSPBP1 common genes common pathways GO:0006954| inflammatory response PTGS2;CRP GO:0097756| CRP;PTGS2 39020:[DB00480 DB09064] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09064|Ciprofibrate PPARA common genes common pathways GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA GO:0006629| lipid metabolic process PTGS2;PPARA 39021:[DB00480 DB06145] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06145|Spiramycin rplC;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39022:[DB00480 DB03451] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03451|1-alpha, 25-dihydroxyl-20-epi-22-oxa-24, 26 ,27-trihomovitamin D3 VDR common genes common pathways GO:0007275| multicellular organismal development TNFSF11;VDR GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 GO:0046697| decidualization VDR;PTGS2 GO:0009887| organ morphogenesis TNFSF11;VDR 39023:[DB00480 DB12118] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12118|Sotatercept ACVR2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ACVR2A 39024:[DB00480 DB02039] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02039|S-Acetyl-Cysteine KAT5;fabH common genes common pathways GO:0043161| proteasomal ubiquitin-dependent protein catabolic process KAT5;CRBN GO:0045944| positive regulation of transcription from RNA polymerase II promoter KAT5;TNFSF11 39025:[DB00480 DB05234] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05234|LGD2941 AR common genes common pathways GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR 39026:[DB00480 DB05542] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05542|Naronapride HTR4 common genes common pathways 39027:[DB00480 DB04757] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04757|GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE PNP common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;PNP GO:0006955| immune response PNP;TNFSF11 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 39028:[DB00480 DB03435] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03435|Uridine-5'-Diphosphate EXTL2;GLT6D1;CMPK1;B3GAT3;ABO;pol;B3GAT1;otsA;GYG1 common genes common pathways 39029:[DB00480 DB04244] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04244|(2R)-2-(3-Biphenylyl)-N-{(2R)-2-hydroxy-3-[(2-pyridinylsulfonyl)amino]propyl}-4-methylpentanamide CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 39030:[DB00480 DB02267] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02267|Argininosuccinate ASL;argG common genes common pathways 39031:[DB00480 DB08159] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08159|4-(5,11-DIOXO-5H-INDENO[1,2-C]ISOQUINOLIN-6(11H)-YL)BUTANOATE TOP1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;TOP1 39032:[DB00480 DB08101] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08101|2,6-dibromo-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport ABCB1;TTR 39033:[DB00480 DB12688] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12688|Moxetumomab Pasudotox CD22;EEF2 common genes common pathways GO:0007568| aging EEF2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;EEF2 GO:0007155| cell adhesion CDH5;CD22 GO:0042493| response to drug EEF2;PTGS2;ABCB1 39034:[DB00480 DB00794] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;CYP1A2 GO:0007613| memory CHRNA7;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0019233| sensory perception of pain PTGS2;CHRNA4 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2;CYP2C9 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0010033| response to organic substance UGT1A1;PTGS2;CYP1A2 GO:0006810| transport GABRA1;GABRB3;GABRG2;ABCB1;GABRB2;GABRA5;GABRA3;GRIK2;GABRA6;GABRA4;GABRB1;GABRD GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0055114| oxidation-reduction process CYP1A2;CYP2C9;CYP2B6;CYP3A4;PTGS2;CYP2C19;CYP2C8 GO:0042493| response to drug CYP1A2;ABCB1;GABRG3;UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1;CYP1A2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 39035:[DB00480 DB02282] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02282|5'-Deoxy-5'-Methylthioadenosine MTAP common genes common pathways 39036:[DB00480 DB06039] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06039|PA-1050040 gag common genes common pathways 39037:[DB00480 DB02311] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02311|Methyl Methylsulfinylmethyl Sulfide FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A GO:0019221| cytokine-mediated signaling pathway FKBP1A;TNFSF11 39038:[DB00480 DB04069] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04069|5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine DAPK1 common genes common pathways GO:0043066| negative regulation of apoptotic process DAPK1;PTGS2 39039:[DB00480 DB00178] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0006954| inflammatory response PTGS2;BDKRB1 GO:0019233| sensory perception of pain PTGS2;BDKRB1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0008217| regulation of blood pressure PTGS2;ACE GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0032496| response to lipopolysaccharide PTGS2;BDKRB1 GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 39040:[DB00480 DB00592] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0006810| transport ABCB1;GABRB3 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 39041:[DB00480 DB01160] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01160|Dinoprost Tromethamine PTGFR;PTGIR;SLC22A2;SLC22A6;SLC22A7;SLC22A8;SLC22A11;SLCO2A1;SLCO3A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0032496| response to lipopolysaccharide PTGIR;PTGS2;PTGFR GO:0008284| positive regulation of cell proliferation PTGFR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGFR;PTGS2 GO:0032355| response to estradiol stimulus PTGFR;PTGS2 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLCO2A1;SLC22A11;SLCO3A1;SLC22A2;SLC22A6;SLC22A7;SLC22A8 39042:[DB00480 DB13996] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13996|Magnesium acetate ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1;PTGS2 GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 39043:[DB00480 DB09571] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09571|Levmetamfetamine PNMT common genes common pathways 39044:[DB00480 DB09227] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0055085| transmembrane transport CACNA1C;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39045:[DB00480 DB00815] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00815|Sodium lauryl sulfate ALB common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| PTGS2;ALB 39046:[DB00480 DB03253] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03253|(2s)-Pyrrolidin-2-Ylmethylamine DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 39047:[DB00480 DB00925] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1D;PTGS2;ADRA1B;ADRA1A GO:0006855| drug transmembrane transport SLC22A2;SLC22A1;ABCB1;SLC22A3 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B;ADRA1A;ADRA1D;ADRA2C GO:0045453| bone resorption ADRB2;TNFSF11 GO:0007275| multicellular organismal development ADRA1D;TNFSF11;ADRA1B GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0055085| transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2;CALM1 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0007568| aging ADRA1A;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug PTGS2;ADRA1A;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0008284| positive regulation of cell proliferation ADRA2A;ADRA1D;PTGS2 39048:[DB00480 DB12418] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12418|Saccharin CA3 common genes common pathways GO:0006979| response to oxidative stress CA3;PTGS2 39049:[DB00480 DB08162] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08162|Fasudil PKIA;PRKACA;ROCK1;ROCK2 common genes common pathways GO:2000114| regulation of establishment of cell polarity CDH5;ROCK2;ROCK1 GO:0034605| cellular response to heat PRKACA;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle PRKACA;ABCB1 39050:[DB00480 DB07837] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07837|[4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid SGK1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;SGK1 GO:0008217| regulation of blood pressure SGK1;PTGS2 39051:[DB00480 DB01811] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01811|3h-Indole-5,6-Diol LTF common genes common pathways GO:0001503| ossification LTF;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;LTF GO:0051092| positive regulation of NF-kappaB transcription factor activity LTF;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;LTF 39052:[DB00480 DB00449] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0007568| aging ADRA1A;PTGS2 GO:0042493| response to drug ADRA1A;PTGS2;BCHE;ABCB1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0007155| cell adhesion CDH5;ACHE GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5;BCHE GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A GO:0050873| brown fat cell differentiation ADRB2;PTGS2 39053:[DB00480 DB12061] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD3;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;HTR1A;PTGS2 GO:0007612| learning PTGS2;DRD3 GO:0042493| response to drug DRD3;ABCB1;DRD2;PTGS2 39054:[DB00480 DB06215] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;FTH1;PTGS2 GO:0006955| immune response FTH1;TNFSF11 GO:0055114| oxidation-reduction process FTH1;PTGS2 39055:[DB00480 DB01444] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01444|Dimethylthiambutene OPRM1;OPRD1 common genes common pathways GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006955| immune response TNFSF11;OPRD1 GO:0009314| response to radiation OPRM1;PTGS2 GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 39056:[DB00480 DB09167] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0010033| response to organic substance CYP1A2;SLC6A4;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2A GO:0055085| transmembrane transport SLC6A2;SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0006810| transport ABCB1;SLC6A2 GO:0007568| aging ADRA1A;HTR2A;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP1A2;CYP2D6;CYP2C9 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug SLC6A2;PTGS2;ADRA1A;HTR2A;ABCB1;SLC6A4;CYP1A2 GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;PTGS2;ADRA2A;CHRM1;ADRA1D GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D;CHRM3 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;ADRA2C;ADRA1D;HTR2A;ADRA1A;PTGS2;ADRA1B GO:0007613| memory SLC6A4;HRH1;PTGS2;HTR2A GO:0006954| inflammatory response HRH1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP2D6;CYP1A2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D 39057:[DB00480 DB05417] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05417|GW 468816 GLRA1 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;GLRA1 39058:[DB00480 DB02338] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02338|Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate TXNRD1;zwf;DPYD;AASS common genes common pathways GO:0055114| oxidation-reduction process PTGS2;TXNRD1;AASS;DPYD GO:0098869| PTGS2;TXNRD1 39059:[DB00480 DB01973] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 39060:[DB00480 DB02508] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways GO:0006629| lipid metabolic process PTGS2;FDPS 39061:[DB00480 DB04113] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04113|N-Formylpiperidine ADH1C common genes common pathways GO:0055114| oxidation-reduction process ADH1C;PTGS2 39062:[DB00480 DB02473] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02473|6-[N-(1-Isopropyl-3,4-Dihydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PLAU GO:0042127| regulation of cell proliferation PLAU;PTGS2 39063:[DB00480 DB07664] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07664|5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE CSNK1G3;SLK;CAMK4;CLK3;ABL2 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;ABL2 GO:0007155| cell adhesion ABL2;CDH5 GO:0045670| regulation of osteoclast differentiation TNFSF11;CAMK4 GO:0006954| inflammatory response PTGS2;CAMK4 39064:[DB00480 DB08493] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08493|5-METHYL-3-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YLCARBAMOYL)-HEXANOIC ACID MMP7 common genes common pathways GO:0007568| aging MMP7;PTGS2 GO:0071260| cellular response to mechanical stimulus MMP7;PTGS2 39065:[DB00480 DB03850] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03850|Jaspisamide A ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 39066:[DB00480 DB09340] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09340|Tyropanoic acid GUSB common genes common pathways 39067:[DB00480 DB06248] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06248|Amelubant LTB4R2;LTB4R common genes common pathways GO:0006954| inflammatory response LTB4R;PTGS2 GO:0006955| immune response LTB4R;TNFSF11 39068:[DB00480 DB00825] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;TRPA1 GO:0010033| response to organic substance PTGS2;TRPA1 GO:0055085| transmembrane transport ABCB1;CACNA1F;TRPA1;TRPV3;TRPM8;CACNA1S;CACNA1D;CACNA1C GO:0006810| transport ABCB1;CACNB4;CACNB3;CACNB1 GO:0006955| immune response TNFSF11;OPRK1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0009314| response to radiation PTGS2;OPRK1 GO:0019233| sensory perception of pain TRPA1;OPRK1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;TRPA1 39069:[DB00480 DB04685] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04685|1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE DUT common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;DUT 39070:[DB00480 DB04072] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04072|Alpha-Methylisocitric Acid ACO2 common genes common pathways 39071:[DB00480 DB00030] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0007566| embryo implantation IGFBP7;PTGS2 GO:0007613| memory PTGS2;INSR GO:0014070| response to organic cyclic compound IGFBP7;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;RB1;IGFBP7;CDH5 GO:0001525| angiogenesis NOV;PTGS2 GO:0006629| lipid metabolic process LRP2;PTGS2 GO:0006955| immune response TNFSF11;IGF1R GO:0010469| regulation of receptor activity NOV;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR GO:0051260| protein homooligomerization TNFSF11;IDE GO:0009887| organ morphogenesis INSR;TNFSF11 GO:0007612| learning PTGS2;INSR GO:0045786| negative regulation of cell cycle RB1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;IGF1R GO:0008284| positive regulation of cell proliferation IGF1R;PTGS2;INSR GO:0045944| positive regulation of transcription from RNA polymerase II promoter RB1;TNFSF11 GO:0007155| cell adhesion CDH5;IGFBP7 GO:0050728| negative regulation of inflammatory response NOV;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;INSR 39072:[DB00480 DB00796] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00796|Candesartan cilexetil AGTR1;CYP2C9;CYP2C8;UGT1A3;PTGS1;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0006810| transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C9;PTGS1;PTGS2;CYP2C8 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation PTGS2;AGTR1;PTGS1 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006855| drug transmembrane transport ABCB1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0019722| calcium-mediated signaling AGTR1;TNFSF11 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9 39073:[DB00480 DB08482] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08482|[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER MMP1 common genes common pathways 39074:[DB00480 DB07696] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07696|methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate CASP3 common genes common pathways GO:0014070| response to organic cyclic compound CASP3;PTGS2 GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CASP3 GO:0010033| response to organic substance PTGS2;CASP3 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0042493| response to drug ABCB1;CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process CASP3;PTGS2 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0032496| response to lipopolysaccharide CASP3;PTGS2 39075:[DB00480 DB03650] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03650|(3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One PIM1 common genes common pathways GO:0007275| multicellular organismal development PIM1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;PIM1 39076:[DB00480 DB11995] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A8;ABCG2 GO:0006810| transport ABCB1;ABCG2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;MPL GO:0099040| ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP2C9 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCG2;ABCB1 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP2C9 39077:[DB00480 DB06457] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06457|Tecastemizole KCNH2 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2 39078:[DB00480 DB05413] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05413|Tifuvirtide SERPINA5 common genes common pathways 39079:[DB00480 DB07117] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;MMP9 GO:0001503| ossification MMP9;TNFSF11 GO:0007566| embryo implantation PTGS2;MMP9 GO:0043066| negative regulation of apoptotic process MMP9;PTGS2 39080:[DB00480 DB06371] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06371|Siplizumab CD2 common genes common pathways GO:0007155| cell adhesion CD2;CDH5 GO:0098609| CD2;CDH5 39081:[DB00480 DB06602] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06602|Reslizumab IL5 common genes common pathways GO:0010469| regulation of receptor activity IL5;TNFSF11 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL5 GO:0008284| positive regulation of cell proliferation IL5;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL5;TNFSF11 GO:0006955| immune response IL5;TNFSF11 GO:0006954| inflammatory response IL5;PTGS2 39082:[DB00480 DB04119] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04119|Hexatantalum Dodecabromide CAMK2A;UBA1 common genes common pathways GO:0030154| cell differentiation TNFSF11;CAMK2A GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CAMK2A GO:0016567| protein ubiquitination CRBN;UBA1 39083:[DB00480 DB07930] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07930|(3R)-3-HYDROXYDODECANOIC ACID ACOX1 common genes common pathways GO:0006693| prostaglandin metabolic process ACOX1;PTGS2 GO:0006629| lipid metabolic process PTGS2;ACOX1 GO:0006631| fatty acid metabolic process PTGS2;ACOX1 GO:0055114| oxidation-reduction process PTGS2;ACOX1 39084:[DB00480 DB11949] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11949|Vestipitant TACR1 common genes common pathways GO:0014070| response to organic cyclic compound TACR1;PTGS2 GO:0008217| regulation of blood pressure TACR1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;TACR1 GO:0045907| positive regulation of vasoconstriction PTGS2;TACR1 GO:0006954| inflammatory response TACR1;PTGS2 GO:0019233| sensory perception of pain TACR1;PTGS2 GO:0032355| response to estradiol stimulus TACR1;PTGS2 39085:[DB00480 DB00734] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0007613| memory DRD1;HTR2A;PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HTR2A;ADRA1A;PTGS2;ADRA1B;HRH1;ADRA2C GO:0008285| negative regulation of cell proliferation DRD2;ADRA1A;PTGS2;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;ADRA1B;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0007275| multicellular organismal development TNFSF11;ADRA1B GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0007568| aging ADRA1A;HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11;ADRA2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007612| learning PTGS2;DRD1;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11 GO:0008284| positive regulation of cell proliferation DRD3;ADRA2A;HTR1A;PTGS2;HTR2A GO:0055114| oxidation-reduction process PTGS2;CYP3A5;CYP3A7;CYP3A4;CYP2D6 GO:0042493| response to drug DRD3;ABCB1;HTR2C;PTGS2;DRD2;ADRA1A;HTR2A;DRD1 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A 39086:[DB00480 DB07500] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07500|(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;PTGS2 GO:0006629| lipid metabolic process PLA2G2E;PTGS2 39087:[DB00480 DB03195] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03195|Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways 39088:[DB00480 DB01704] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01704|2,4-Dihydroxy-Trans Cinnamic Acid CTRB1 common genes common pathways 39089:[DB00480 DB12874] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12874|Quizartinib FLT3 common genes common pathways GO:0030154| cell differentiation FLT3;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;FLT3 GO:0019221| cytokine-mediated signaling pathway TNFSF11;FLT3 GO:0010243| response to organic nitrogen PTGS2;FLT3 GO:0008284| positive regulation of cell proliferation FLT3;PTGS2 39090:[DB00480 DB05750] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05750|AVE-1625 CNR1 common genes common pathways GO:0032496| response to lipopolysaccharide CNR1;PTGS2 GO:0007568| aging PTGS2;CNR1 GO:0043065| positive regulation of apoptotic process CNR1;PTGS2 GO:0031622| positive regulation of fever generation CNR1;PTGS2 GO:0019233| sensory perception of pain PTGS2;CNR1 GO:0007613| memory PTGS2;CNR1 39091:[DB00480 DB07127] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07127|{4-[2,2-BIS(5-METHYL-1,2,4-OXADIAZOL-3-YL)-3-PHENYLPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways GO:0001525| angiogenesis PTPRB;PTGS2 39092:[DB00480 DB05394] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05394|Corticorelin DBH common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;DBH GO:0007613| memory DBH;PTGS2 GO:0042127| regulation of cell proliferation DBH;PTGS2 GO:0055114| oxidation-reduction process DBH;PTGS2 39093:[DB00480 DB04115] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04115|Berberine BIRC5 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process BIRC5;PTGS2 GO:0016567| protein ubiquitination BIRC5;CRBN GO:0043066| negative regulation of apoptotic process PTGS2;BIRC5 GO:0008284| positive regulation of cell proliferation BIRC5;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;BIRC5 39094:[DB00480 DB02660] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02660|Filaminast PDE4B common genes common pathways 39095:[DB00480 DB13781] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13781|Xamoterol ADRB1 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;ADRB1 39096:[DB00480 DB00653] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways GO:0006810| transport CACNG1;CACNB1;ABCB1 GO:0055085| transmembrane transport ABCB1;CACNA1C;CACNA1S 39097:[DB00480 DB01147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0098869| ALB;PTGS2 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport SLC22A6;SLC15A2;SLC15A1;ABCB1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 39098:[DB00480 DB02932] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02932|(R)-Bicalutamide AR common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development TNFSF11;AR 39099:[DB00480 DB07677] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07677|2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one PARP3 common genes common pathways 39100:[DB00480 DB07592] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07592|(2R)-3-Methyl-1-phenyl-2-butanyl [(2S)-1-oxo-2-hexanyl]carbamate CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 39101:[DB00480 DB04117] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04117|4-(N,N-Dimethylamino)Cinnamoyl-Coa ECHS1 common genes common pathways GO:0006629| lipid metabolic process ECHS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;ECHS1 39102:[DB00480 DB02758] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02758|Indolylpropionic Acid tyrB;PLA2G2E common genes common pathways GO:0006954| inflammatory response PLA2G2E;PTGS2 GO:0006629| lipid metabolic process PLA2G2E;PTGS2 39103:[DB00480 DB07509] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07509|difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron PPARG common genes common pathways GO:0010033| response to organic substance PTGS2;PPARG GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;PTGS2 39104:[DB00480 DB01647] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01647|Daxalipram PDE4B common genes common pathways 39105:[DB00480 DB00869] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP3A4 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0045780| positive regulation of bone resorption TNFSF11;CA2 GO:0006979| response to oxidative stress CA3;PTGS2 GO:0010033| response to organic substance PTGS2;CA2 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS2 39106:[DB00480 DB02589] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02589|Se-Ethyl-Isoselenourea NOS3 common genes common pathways GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation CDH5;NOS3;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 39107:[DB00480 DB04276] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04276|N-[N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-Butyl]-Guanidine CAPN1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CAPN1 39108:[DB00480 DB03849] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03849|Cilomilast PDE4D;PDE4B common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity PDE4D;TNFSF11 39109:[DB00480 DB07701] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07701|1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 39110:[DB00480 DB02822] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02822|Para-Bromobenzyl Alcohol ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 39111:[DB00480 DB11636] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11636|Nomegestrol CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39112:[DB00480 DB07561] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07561|(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0042493| response to drug PTGS2;DHODH;ABCB1 39113:[DB00480 DB00147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00147|Pyridoxal PDXK common genes common pathways 39114:[DB00480 DB01541] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01541|Boldenone AR common genes common pathways GO:0006810| transport ABCB1;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0042327| positive regulation of phosphorylation AR;TNFSF11 39115:[DB00480 DB00998] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;HTR1B;ABCB1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 39116:[DB00480 DB00133] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1 GO:0007568| aging PTGS2;SRR GO:0042493| response to drug PTGS2;SRR;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CBS GO:0032496| response to lipopolysaccharide PTGS2;SRR GO:0014070| response to organic cyclic compound SRR;PTGS2 GO:0051384| response to glucocorticoid stimulus AGXT;PTGS2 GO:0006629| lipid metabolic process PTGS2;SPTLC1;SPTLC2 39117:[DB00480 DB07252] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07252|3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide EPHB4 common genes common pathways GO:0007155| cell adhesion EPHB4;CDH5 GO:0007275| multicellular organismal development TNFSF11;EPHB4 GO:0001525| angiogenesis PTGS2;EPHB4 39118:[DB00480 DB05422] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05422|OPC-14523 SLC6A4 common genes common pathways GO:0007613| memory PTGS2;SLC6A4 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0055085| transmembrane transport SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0042493| response to drug ABCB1;SLC6A4;PTGS2 39119:[DB00480 DB13749] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0010226| response to lithium ion ADCY1;PTGS2 GO:0051384| response to glucocorticoid stimulus PFKFB1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;ATP1A1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ABL1 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0043065| positive regulation of apoptotic process ABL1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1 GO:0007155| cell adhesion CDH5;ABL1 GO:0042493| response to drug ABCB1;ADCY1;PTGS2;ATP1A1 39120:[DB00480 DB12089] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39121:[DB00480 DB07173] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 39122:[DB00480 DB09061] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes PTGS2 common pathways GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A1;SOD1;PPARG;TRPA1;CYP1A2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007043| cell-cell junction assembly TRPV4;CDH5 GO:0055085| transmembrane transport TRPV1;ABCC1;TRPV4;ABCG2;TRPM8;CACNA1H;TRPV3;TRPV2;CACNA1G;VDAC1;CACNA1I;TRPA1;ABCB1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0098869| PTGS1;PTGS2;CAT;GSR;GPX1 GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2;OPRM1 GO:0006979| response to oxidative stress CAT;GPX1;PTGS1;SOD1;PTGS2 GO:0051260| protein homooligomerization ACAT1;GLRA3;GLRA1;TNFSF11 GO:0007568| aging CNR1;CAT;HMGCR;PTGS2;NAPEPLD;CYP1A1;SOD1;HTR2A GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization ALOX15;PTGS2 GO:0006810| transport ABCG2;ABCC1;TRPV2;TRPV1;ABCB1;CACNA1I GO:0097756| ADORA1;PTGS2;HMGCR GO:0071456| cellular response to hypoxia PTGS2;OPRD1;SLC29A1 GO:0034605| cellular response to heat TRPV4;PTGS2;TRPV1 GO:0032355| response to estradiol stimulus PTGS2;CAT;CYP1A2 GO:1902219| PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMGCR GO:0019372| lipoxygenase pathway ALOX15;GPX1;ALOX5;PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0050728| negative regulation of inflammatory response ADORA1;CDH5;CNR2 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process IDO1;CYP2C19;PTGS2;HMGCR;CYP1A1;CYP3A5;CYP17A1;CYP3A7;SOD1;ALOX5;PTGS1;CYP1B1;GSR;CYP3A4;GPX1;CYP2C9;CRYZ;ALOX15;CYP2D6;CYP1A2;CAT GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process ALOX15;PTGS1;PTGS2 GO:0042493| response to drug SOD1;HTR2A;CYP1A1;PTGS2;SMPD1;ABCC1;ABCG2;CYP1A2;CAT;TRPA1;PPARG;ABCB1 GO:0034097| response to cytokine stimulus AANAT;PTGS2 GO:0007155| cell adhesion CDH5;CYP1B1 GO:0043066| negative regulation of apoptotic process GPX1;ADORA1;CAT;PTGS2;HMGCR;SOD1 GO:0045786| negative regulation of cell cycle PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PLA2G1B;PPARG;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR1A;HMGCR;PTGS2;CHRNA7;HTR2A GO:0046330| positive regulation of JNK cascade TNFSF11;TRPV4 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2;TRPV1;SOD1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2;VDAC1 GO:0032496| response to lipopolysaccharide CYP1A2;OPRM1;CNR1;CNR2;CYP1A1;PTGS2;IDO1 GO:0008285| negative regulation of cell proliferation ADORA1;CDH5;OPRM1;PPARG;CYP1B1;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS1;SOD1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 GO:0014070| response to organic cyclic compound PTGS2;AANAT;ACAT1;CYP1A1;PPARG;TRPA1;CYP1A2 GO:0033280| response to vitamin D PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2;CAT GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1;PLA2G1B GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0045453| bone resorption TNFSF11;GPR55 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory CNR1;CHRNA7;PTGS2;HTR2A GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation SOD1;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1;TRPV4 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006955| immune response TNFSF11;CNR2;OPRD1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity PLA2G1B;CAT;TNFSF11 GO:0006954| inflammatory response ALOX15;ADORA1;PTGS1;ALOX5;CNR2;TRPV1;PTGS2;IDO1 GO:0010942| positive regulation of cell death PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;GPX1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006629| lipid metabolic process CYP1A2;CYP2D6;ALOX15;CYP2C9;GPX1;CYP3A4;PLA2G1B;PPARG;PTGS1;DAGLA;TRPV1;NAAA;NAPEPLD;HMGCR;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0001503| ossification TNFSF11;ALOX15 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0043065| positive regulation of apoptotic process SOD1;TRPV1;PTGS2;SMPD1;IDO1;CNR1;PPARG;CYP1B1 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2;OPRM1;CAT GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0019233| sensory perception of pain TRPA1;OPRM1;CNR1;OPRD1;PTGS2;TRPV1;CNR2;HTR2A GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 39123:[DB00480 DB08276] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08276|trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-) MYH14 common genes common pathways 39124:[DB00480 DB02890] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02890|6-Hydroxyuridine-5'-Phosphate UMPS;pyrF common genes common pathways 39125:[DB00480 DB00066] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00066|Follitropin FSHR common genes common pathways GO:0045670| regulation of osteoclast differentiation TNFSF11;FSHR 39126:[DB00480 DB01873] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0000086| G2/M transition of mitotic cell cycle TUBA4A;ABCB1;TUBA1A;TUBB4A;TUBB4B;TUBB GO:0006629| lipid metabolic process CYP3A4;PTGS2 39127:[DB00480 DB08809] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08809|Dichloroacetic Acid PDK1;GSTZ1 common genes common pathways GO:0098869| GSTZ1;PTGS2 39128:[DB00480 DB11595] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11595|Atezolizumab CD274 common genes common pathways GO:0034097| response to cytokine stimulus CD274;PTGS2 GO:0006955| immune response TNFSF11;CD274 39129:[DB00480 DB01751] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01751|3,3',5,5'-Tetraiodothyroacetic Acid TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport TTR;ABCB1 39130:[DB00480 DB02774] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02774|1,3-Propandiol ARF1 common genes common pathways 39131:[DB00480 DB04856] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04856|Dexloxiglumide CCKAR;CYP3A5;CYP3A4;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP3A5;PTGS2 39132:[DB00480 DB01582] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01582|Sulfamethazine ALB common genes common pathways GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB 39133:[DB00480 DB00397] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0007613| memory PTGS2;DRD1 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA2C;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;MAOA GO:0042493| response to drug DRD1;PTGS2;ABCB1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0007612| learning DRD1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 39134:[DB00480 DB03944] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03944|5-[1-(3,4-Dimethoxy-Benzoyl)-1,2,3,4-Tetrahydro-Quinolin-6-Yl]-6-Methyl-3,6-Dihydro-[1,3,4]Thiadiazin-2-One TNNC1 common genes common pathways 39135:[DB00480 DB03413] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03413|Deoxyuridine-5'-Diphosphate DUT;dut;dut;pol common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;DUT 39136:[DB00480 DB04466] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04466|SR12813 NR1I2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TNFSF11 39137:[DB00480 DB07629] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07629|N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 39138:[DB00480 DB02115] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02115|Daidzin ALDH2;ABCG2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0042493| response to drug ABCG2;PTGS2;ABCB1 GO:0055114| oxidation-reduction process ALDH2;PTGS2 39139:[DB00480 DB09310] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09310|Coagulation Factor XIII A-Subunit (Recombinant) F13B common genes common pathways 39140:[DB00480 DB03706] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03706|1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane GSTM4 common genes common pathways 39141:[DB00480 DB08047] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08047|4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol ESR1;NCOA2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;NCOA2 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 39142:[DB00480 DB05012] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0042493| response to drug SLC6A2;PTGS2;ABCB1 39143:[DB00480 DB07681] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07681|DODECANESULFONATE ION BCHE common genes common pathways GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug PTGS2;BCHE;ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 39144:[DB00480 DB00728] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0055085| transmembrane transport SLCO1A2;ABCB1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 39145:[DB00480 DB02636] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02636|9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid PLA2G2E common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;PTGS2 GO:0006954| inflammatory response PTGS2;PLA2G2E 39146:[DB00480 DB03026] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03026|Phosphoglycolohydroxamic Acid TPI1;fucA common genes common pathways GO:0007275| multicellular organismal development TNFSF11;TPI1 39147:[DB00480 DB03017] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03017|Lauric Acid ADH5;fabB;GM2A;fabH;HNF4A;PLA2G2A;VLDLR;GLTP;fabF;LTF;tonB;C8G;PLA2G2D;LY96;TLR4;PPARA;ALB common genes common pathways GO:0050727| regulation of inflammatory response TLR4;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;TLR4 GO:0006629| lipid metabolic process PLA2G2D;HNF4A;PTGS2;VLDLR;PPARA;GM2A;PLA2G2A GO:0001503| ossification TNFSF11;LTF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;LTF;TNFSF11 GO:0006955| immune response TNFSF11;TLR4 GO:0006954| inflammatory response TLR4;PLA2G2D;PTGS2;LY96 GO:0051092| positive regulation of NF-kappaB transcription factor activity TLR4;TNFSF11;LTF GO:0007613| memory PTGS2;VLDLR GO:0008285| negative regulation of cell proliferation HNF4A;PTGS2;CDH5 GO:0043066| negative regulation of apoptotic process LTF;ALB;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;TNFSF11;TLR4;HNF4A GO:0032496| response to lipopolysaccharide LY96;ADH5;TLR4;PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;TLR4 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0055114| oxidation-reduction process PTGS2;ADH5 GO:0098869| PTGS2;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TLR4 39148:[DB00480 DB04436] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04436|3-Fluorotyrosine SOD2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;SOD2 GO:0008285| negative regulation of cell proliferation PTGS2;SOD2;CDH5 GO:0008217| regulation of blood pressure SOD2;PTGS2 39149:[DB00480 DB03825] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03825|Rhodamine 6G ABCC1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 39150:[DB00480 DB13876] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13876|Brofaromine MAOA common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2 39151:[DB00480 DB04374] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04374|4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole HAO1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HAO1 GO:0006979| response to oxidative stress PTGS2;HAO1 39152:[DB00480 DB09047] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 39153:[DB00480 DB00643] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP1A1 GO:0042493| response to drug PTGS2;CYP1A1;ABCB1 GO:0007568| aging CYP1A1;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle TUBB4B;TUBA1A;ABCB1 GO:0010033| response to organic substance CYP1A1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 39154:[DB00480 DB01666] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01666|D-Myo-Inositol-Hexasulphate FST common genes common pathways 39155:[DB00480 DB04121] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04121|Guanosine-3'-Monophosphate-5'-Diphosphate ARF1 common genes common pathways 39156:[DB00480 DB08631] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08631|N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE PNMT common genes common pathways 39157:[DB00480 DB06249] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06249|Arzoxifene ESR1;ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 39158:[DB00480 DB08564] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08564|(2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide SRC common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0007155| cell adhesion CDH5;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0034332| adherens junction organization CDH5;SRC GO:1902533| TNFSF11;SRC GO:0098609| CDH5;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0070542| response to fatty acid PTGS2;SRC 39159:[DB00480 DB04941] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04941|Crofelemer CFTR;ANO1 common genes common pathways GO:0055085| transmembrane transport ABCB1;CFTR GO:0034605| cellular response to heat PTGS2;ANO1 GO:0007275| multicellular organismal development TNFSF11;ANO1 39160:[DB00480 DB06133] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06133|Dimethylcurcumin AR common genes common pathways GO:0006810| transport AR;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR 39161:[DB00480 DB07193] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07193|(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion DPP4;CDH5 39162:[DB00480 DB08922] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A;HTR2A;ADRA1D GO:0042493| response to drug PTGS2;CYP1A1;DRD2;ADRA1A;HTR2A;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP1A1;CYP3A4;CYP2D6 GO:0007568| aging PTGS2;CYP1A1;ADRA1A;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0006954| inflammatory response PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction ADRA1D;HRH1;PTGS2;ADRA1B;HTR2A;ADRA1A GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1A;ADRA1D GO:0008285| negative regulation of cell proliferation CDH5;DRD2;ADRA1A;PTGS2 39163:[DB00480 DB07754] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07754|N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acid FOLH1 common genes common pathways 39164:[DB00480 DB12379] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12379|Indirubin CYP1A1;AHR common genes common pathways GO:0042493| response to drug PTGS2;CYP1A1;ABCB1 GO:0055114| oxidation-reduction process CYP1A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AHR GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0007568| aging PTGS2;CYP1A1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 39165:[DB00480 DB01576] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging PTGS2;SLC6A3;ADRA1A GO:0055085| transmembrane transport SLC6A2;SLC18A2;SLC6A3;ABCB1 GO:0042493| response to drug ABCB1;SLC6A2;PTGS2;ADRA1A;SLC6A3 GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;ADRA1B;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0007275| multicellular organismal development ADRA1B;TNFSF11 39166:[DB00480 DB00647] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00647|Dextropropoxyphene OPRM1;OPRD1;OPRK1;CES1;CYP3A4;CYP2D6;CYP2C8 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP2D6;CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11;OPRD1 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0009314| response to radiation PTGS2;OPRM1;OPRK1 GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRK1;OPRM1 39167:[DB00480 DB13999] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0042493| response to drug PTGS2;CALR;ABCB1 GO:0006631| fatty acid metabolic process PTGS2;PHYH GO:0055114| oxidation-reduction process PTGS2;PHYH GO:0050728| negative regulation of inflammatory response PROC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;CALR;F2 GO:0043066| negative regulation of apoptotic process PROC;HSPA5;PTGS2 GO:0007155| cell adhesion VWF;CDH5 GO:0010033| response to organic substance CALR;PTGS2 GO:0010469| regulation of receptor activity F2;TNFSF11 GO:0032355| response to estradiol stimulus CALR;PTGS2 GO:0030282| bone mineralization PTGS2;ASGR2 GO:0007568| aging LRP1;CANX;PTGS2 GO:0051260| protein homooligomerization VWF;TNFSF11 GO:0010942| positive regulation of cell death PTGS2;LRP1 GO:0007275| multicellular organismal development LRP1;F2;TNFSF11 GO:0009314| response to radiation PTGS2;HSPA5 GO:0006629| lipid metabolic process LRP1;PTGS2 GO:1903142| PROC;CDH5 39168:[DB00480 DB07326] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07326|6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide KDR common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0001525| angiogenesis PTGS2;KDR GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0030154| cell differentiation TNFSF11;KDR 39169:[DB00480 DB06205] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06205|Hyaluronidase (Human Recombinant) TGFB1;ALB common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;TGFB1 GO:0010033| response to organic substance TGFB1;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;TGFB1 GO:0098869| PTGS2;ALB GO:0010469| regulation of receptor activity TNFSF11;TGFB1 GO:0032355| response to estradiol stimulus TGFB1;PTGS2 GO:0007568| aging PTGS2;TGFB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TGFB1 GO:0042493| response to drug TGFB1;ABCB1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;TGFB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TGFB1 GO:0045786| negative regulation of cell cycle TGFB1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0042127| regulation of cell proliferation TGFB1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;TGFB1;CDH5 GO:0033280| response to vitamin D TGFB1;PTGS2 GO:0014070| response to organic cyclic compound TGFB1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TGFB1;PTGS2 GO:0006954| inflammatory response TGFB1;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TGFB1;TNFSF11 GO:0042307| positive regulation of protein import into nucleus PTGS2;TGFB1 GO:0009314| response to radiation TGFB1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;TGFB1 GO:0071260| cellular response to mechanical stimulus TGFB1;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production TGFB1;PTGS2 39170:[DB00480 DB11450] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11450|Pimobendan CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 39171:[DB00480 DB01838] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01838|6,4'-Dihydroxy-3-Methyl-3',5'-Dibromoflavone TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TTR;TNFSF11 39172:[DB00480 DB08020] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08020|(3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL ESR2;ESR1 common genes common pathways GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1;ESR2 39173:[DB00480 DB02236] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways GO:0010033| response to organic substance GART;PTGS2 39174:[DB00480 DB01185] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01185|Fluoxymesterone AR;ESR1;PRLR;NR3C1;HSD11B2;SHBG common genes common pathways GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0007566| embryo implantation PTGS2;PRLR GO:0051384| response to glucocorticoid stimulus HSD11B2;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0043066| negative regulation of apoptotic process PRLR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;AR;NR3C1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11;PRLR;AR GO:0042493| response to drug HSD11B2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process HSD11B2;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0006810| transport AR;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 39175:[DB00480 DB08320] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08320|DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE ESR1;NCOA2 common genes common pathways GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TNFSF11;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 39176:[DB00480 DB01756] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01756|4-phospho-L-threonic acid RPIA common genes common pathways 39177:[DB00480 DB08022] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08022|(2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile PIM1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;PIM1 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2 39178:[DB00480 DB07512] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07512|7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;MAOB GO:0055114| oxidation-reduction process PTGS2;MAOB 39179:[DB00480 DB06926] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06926|(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid PPARG common genes common pathways GO:0010033| response to organic substance PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG 39180:[DB00480 DB06691] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A4;SLC22A5 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 39181:[DB00480 DB13488] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13488|Bencyclane CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39182:[DB00480 DB07318] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07318|N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 39183:[DB00480 DB08170] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08170|(1R)-N,6-DIHYDROXY-7-METHOXY-2-[(4-METHOXYPHENYL)SULFONYL]-1,2,3,4-TETRAHYDROISOQUINOLINE-1-CARBOXAMIDE MMP7 common genes common pathways GO:0007568| aging MMP7;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;MMP7 39184:[DB00480 DB08180] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08180|2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE FNTA;PGGT1B common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;PGGT1B GO:0034097| response to cytokine stimulus PGGT1B;PTGS2 39185:[DB00480 DB08087] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08087|4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE AR common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AR 39186:[DB00480 DB00146] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00146|Calcifediol VDR;CYP27B1;CYP24A1 common genes common pathways GO:0055114| oxidation-reduction process CYP24A1;PTGS2;CYP27B1 GO:0032496| response to lipopolysaccharide PTGS2;CYP27B1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VDR GO:0009887| organ morphogenesis VDR;TNFSF11 GO:0046697| decidualization VDR;CYP27B1;PTGS2 GO:0030282| bone mineralization CYP27B1;PTGS2 GO:0055074| calcium ion homeostasis TNFSF11;CYP27B1 GO:0007275| multicellular organismal development VDR;TNFSF11 GO:0033280| response to vitamin D PTGS2;CYP27B1;CYP24A1 GO:0008285| negative regulation of cell proliferation CYP27B1;PTGS2;VDR;CDH5 39187:[DB00480 DB06210] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;CYP1A2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;SLCO1B1;ABCB1 GO:0010033| response to organic substance CYP1A2;PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;CYP1A2 GO:0042493| response to drug UGT1A1;ABCG2;PTGS2;CYP1A2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP1A2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;MPL 39188:[DB00480 DB03065] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03065|7-Nitroindazole-2-Carboxamidine NOS3 common genes common pathways GO:0001525| angiogenesis PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;NOS3;CDH5 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 39189:[DB00480 DB06421] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 39190:[DB00480 DB13133] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways GO:0001503| ossification TNFSF11;COL1A1 GO:0071260| cellular response to mechanical stimulus COL1A1;PTGS2 GO:0055114| oxidation-reduction process F8;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;COL1A1 GO:0032355| response to estradiol stimulus PTGS2;COL1A1 GO:0034612| response to tumor necrosis factor PTGS2;ADAMTS13 39191:[DB00480 DB07977] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07977|3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID DHODH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHODH GO:0042493| response to drug PTGS2;DHODH;ABCB1 GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;DHODH 39192:[DB00480 DB00233] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes PTGS2 common pathways GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS2;ALOX5;PLA2G2E;CHUK GO:0010942| positive regulation of cell death PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity CHUK;TNFSF11 GO:0006955| immune response CHUK;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CHUK GO:0031622| positive regulation of fever generation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2;PLA2G2E GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:1990776| PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0055114| oxidation-reduction process PTGS2;ALOX5;MPO GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CHUK GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway ALOX5;PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide MPO;PTGS2;CHUK GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;MPO GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PTGS2;CHUK GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging PTGS2;MPO GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;CHUK GO:0034605| cellular response to heat PTGS2 GO:0006979| response to oxidative stress PTGS2;MPO GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 39193:[DB00480 DB03183] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03183|1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007568| aging PDE4D;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;PDE4D 39194:[DB00480 DB11606] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11606|Susoctocog alfa VWF common genes common pathways GO:0051260| protein homooligomerization TNFSF11;VWF GO:0007155| cell adhesion CDH5;VWF 39195:[DB00480 DB05155] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05155|CR665 OPRK1 common genes common pathways GO:0019233| sensory perception of pain OPRK1;PTGS2 GO:0009314| response to radiation OPRK1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11 39196:[DB00480 DB09080] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0050873| brown fat cell differentiation PTGS2;ADRB2 GO:0006629| lipid metabolic process CYP2C9;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP2C9 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 39197:[DB00480 DB00585] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00585|Nizatidine HRH2;BCHE;ABCB1 common genes ABCB1 common pathways GO:0006955| immune response HRH2;TNFSF11 GO:0006855| drug transmembrane transport ABCB1 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0007613| memory PTGS2;HRH2 GO:0042908| xenobiotic transport ABCB1 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH2 GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0007612| learning PTGS2;BCHE GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 39198:[DB00480 DB00561] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0010469| regulation of receptor activity KCNK3;TNFSF11 GO:0071456| cellular response to hypoxia KCNK3;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;KCNK3 39199:[DB00480 DB02144] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02144|1,2-diacyl-sn-glycero-3-phosphoinositol PITPNA common genes common pathways GO:0006629| lipid metabolic process PITPNA;PTGS2 39200:[DB00480 DB08026] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08026|2-{4-[(4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]piperidin-1-yl}-N-methylacetamide MAPK10 common genes common pathways 39201:[DB00480 DB03021] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03021|Ulapualide A ACTA1 common genes common pathways GO:0010226| response to lithium ion ACTA1;PTGS2 39202:[DB00480 DB06654] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2;CYP1A1 GO:0055085| transmembrane transport SLCO3A1;ABCG2;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0007568| aging PTGS2;CYP1A1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;CYP2B6;CYP2D6;CYP1A2;CYP2C19;MAOA;PTGS2;MAOB;CYP1A1;CYP3A5;CYP2E1 GO:0042493| response to drug ABCG2;PTGS2;CYP1A1;MAOB;CYP2E1;ABCB1;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A1;MAOB;PTGS2;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2;CYP1A2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP2C9;CYP1A2;CYP3A4 39203:[DB00480 DB07227] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07227|4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE FNTA;FNTB;PGGT1B common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway FNTA;CDH5 GO:0034097| response to cytokine stimulus PTGS2;PGGT1B GO:0008284| positive regulation of cell proliferation PGGT1B;PTGS2 GO:0042127| regulation of cell proliferation FNTB;PTGS2 39204:[DB00480 DB02955] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02955|Ricinoleic Acid CNR1;CNR2;TRPV1 common genes common pathways GO:0007613| memory CNR1;PTGS2 GO:0006629| lipid metabolic process TRPV1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;TRPV1;CNR1 GO:0031622| positive regulation of fever generation PTGS2;CNR1 GO:0019233| sensory perception of pain CNR1;TRPV1;CNR2;PTGS2 GO:0006954| inflammatory response CNR2;TRPV1;PTGS2 GO:0006955| immune response CNR2;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TRPV1 GO:0007568| aging CNR1;PTGS2 GO:0006810| transport ABCB1;TRPV1 GO:0034605| cellular response to heat PTGS2;TRPV1 GO:0055085| transmembrane transport ABCB1;TRPV1 GO:0032496| response to lipopolysaccharide PTGS2;CNR2;CNR1 GO:0071318| cellular response to ATP PTGS2;TRPV1 GO:0010243| response to organic nitrogen TRPV1;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;CNR2 39205:[DB00480 DB02553] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02553|Glutathionylspermidine Disulfide GSR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GSR GO:0098869| GSR;PTGS2 39206:[DB00480 DB08529] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08529|(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID) GGPS1 common genes common pathways 39207:[DB00480 DB09266] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09266|Technetium Tc-99m tilmanocept MRC1 common genes common pathways 39208:[DB00480 DB02011] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02011|N-(Phosphonoacetyl)-L-Ornithine OTC common genes common pathways GO:0042493| response to drug PTGS2;OTC;ABCB1 39209:[DB00480 DB04652] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04652|Corticosterone NR3C2;HSD11B1;NCOA1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NCOA1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;HSD11B1 GO:0006629| lipid metabolic process PTGS2;HSD11B1;CYP3A4 GO:0043065| positive regulation of apoptotic process NCOA1;PTGS2 39210:[DB00480 DB04709] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04709|(3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE AR common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0006810| transport AR;ABCB1 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR 39211:[DB00480 DB01612] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways GO:0008217| regulation of blood pressure PTGS2;NPR1 GO:0055114| oxidation-reduction process ALDH2;PTGS2 39212:[DB00480 DB01777] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01777|Coa-S-Trimethylene-Acetyl-Tryptamine AANAT common genes common pathways GO:0034097| response to cytokine stimulus PTGS2;AANAT GO:0014070| response to organic cyclic compound AANAT;PTGS2 39213:[DB00480 DB14518] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0046330| positive regulation of JNK cascade TNFSF11;APP GO:0007612| learning PTGS2;APP GO:0007155| cell adhesion APP;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0042493| response to drug ATP1A1;PTGS2;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;APP GO:0051260| protein homooligomerization TNFSF11;APP GO:0006979| response to oxidative stress PTGS2;APP GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;APP GO:0098869| ALB;PTGS2 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0042327| positive regulation of phosphorylation TNFSF11;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP GO:0007613| memory PTGS2;APP GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;APP GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0008285| negative regulation of cell proliferation APP;CDH5;PTGS2 39214:[DB00480 DB07921] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07921|2-[(4-fluorophenyl)sulfonylamino]-N-oxo-ethanamide MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 39215:[DB00480 DB07684] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07684|5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID PLAT common genes common pathways 39216:[DB00480 DB07300] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07300|2-(1H-imidazol-1-yl)-9-methoxy-8-(2-methoxyethoxy)benzo[c][2,7]naphthyridin-4-amine PDPK1 common genes common pathways GO:0019722| calcium-mediated signaling PDPK1;TNFSF11 39217:[DB00480 DB12733] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12733|Dipraglurant GRM5 common genes common pathways GO:0007612| learning GRM5;PTGS2 39218:[DB00480 DB02735] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02735|2-Amino-3-Oxo-4-Sulfo-Butyric Acid STS common genes common pathways GO:0006629| lipid metabolic process STS;PTGS2 39219:[DB00480 DB00867] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00867|Ritodrine ADRB2;PGD common genes common pathways GO:0055114| oxidation-reduction process PTGS2;PGD GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 39220:[DB00480 DB00169] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00169|Cholecalciferol VDR;CYP2R1;CYP27A1;CYP2J2;CYP3A4;CYP11A1;CYP1A1;CYP2B6;CYP2C8;CYP2D6;GC common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP11A1;CYP2D6;PTGS2 GO:0007275| multicellular organismal development VDR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;VDR;PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0042493| response to drug ABCB1;CYP1A1;PTGS2 GO:0055114| oxidation-reduction process CYP2B6;CYP2D6;CYP2R1;CYP11A1;CYP2J2;CYP3A4;CYP1A1;CYP27A1;CYP2C8;PTGS2 GO:0046697| decidualization PTGS2;VDR GO:0007568| aging CYP1A1;PTGS2 GO:0009887| organ morphogenesis VDR;TNFSF11 GO:0010033| response to organic substance PTGS2;CYP1A1 39221:[DB00480 DB02507] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02507|4-Hydroxy-3-[(1s)-3-Oxo-1-Phenylbutyl]-2h-Chromen-2-One CYP2C9;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;PTGS2 39222:[DB00480 DB03280] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03280|P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate DTYMK;tmk;tmk common genes common pathways 39223:[DB00480 DB06150] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06150|Sulfadimethoxine CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 39224:[DB00480 DB03169] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03169|(S)-Hmg-Coa HMGCR common genes common pathways GO:0006629| lipid metabolic process PTGS2;HMGCR GO:0055114| oxidation-reduction process PTGS2;HMGCR GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR GO:0007568| aging HMGCR;PTGS2 GO:0097756| HMGCR;PTGS2 39225:[DB00480 DB01586] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0010033| response to organic substance PTGS2;ABCC4 GO:0055085| transmembrane transport ABCC2;ABCB1;ABCC4;SLC10A2;SLC10A1;SLCO1A2;ABCB11 GO:0007043| cell-cell junction assembly NR1H4;CDH5 GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0006810| transport SLC10A1;SLC10A2;ABCC2;ABCB1;ABCB11 GO:0050728| negative regulation of inflammatory response NR1H4;CDH5 GO:0010243| response to organic nitrogen ABCC4;CYP2E1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;ABCC4 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C2;TNFSF11 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1;ABCC2;ABCC4 GO:0055114| oxidation-reduction process AKR1C2;ABCC4;PTGS2;CYP2E1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AKR1C2 GO:0043066| negative regulation of apoptotic process PTGS2;NR1H4 GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:0014070| response to organic cyclic compound ABCC4;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0006954| inflammatory response NR1H4;PTGS2 GO:0006693| prostaglandin metabolic process AKR1C2;PTGS2 GO:0006629| lipid metabolic process AKR1C2;PTGS2 39226:[DB00480 DB05495] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05495|PG-530742 MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process MMP9;PTGS2 GO:0043065| positive regulation of apoptotic process MMP9;PTGS2 GO:0001503| ossification MMP9;TNFSF11 GO:0007566| embryo implantation PTGS2;MMP9 39227:[DB00480 DB11113] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11113|Castor oil PTGER3;PTGER4 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;PTGER4 GO:0050728| negative regulation of inflammatory response CDH5;PTGER4 GO:0031622| positive regulation of fever generation PTGS2;PTGER3 GO:0071260| cellular response to mechanical stimulus PTGER4;PTGS2 GO:0006955| immune response PTGER4;TNFSF11 GO:0070371| ERK1 and ERK2 cascade PTGER4;TNFSF11 39228:[DB00480 DB12339] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12339|Radezolid RRBP1;NIP7 common genes common pathways 39229:[DB00480 DB11085] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11085|Resorcinol TPO common genes common pathways GO:0055114| oxidation-reduction process PTGS2;TPO GO:0006979| response to oxidative stress TPO;PTGS2 GO:0098869| TPO;PTGS2 39230:[DB00480 DB07932] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07932|dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate ESR1;NCOA2 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 39231:[DB00480 DB13772] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13772|Rufloxacin CYP1A2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 39232:[DB00480 DB12267] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0042493| response to drug ABCG2;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A5;CYP3A7;CYP3A43;CYP3A4 GO:0010243| response to organic nitrogen PTGS2;FLT3 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2 GO:0019221| cytokine-mediated signaling pathway FLT3;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;ERBB4;MET;TNFSF11;ERBB2;EGFR GO:0042127| regulation of cell proliferation ABL1;ALK;EGFR;PTGS2 GO:0007612| learning PTGS2;INSR GO:0008284| positive regulation of cell proliferation ERBB4;FLT3;INSR;PTGS2;IGF1R;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11;MET GO:0043066| negative regulation of apoptotic process ERBB4;PTGS2;EGFR;IGF1R GO:0007155| cell adhesion ABL1;CDH5 GO:0060749| mammary gland alveolus development TNFSF11;ERBB4 GO:0055085| transmembrane transport SLC22A1;ABCB1;SLC47A2;SLC47A1;ABCG2;ABCB5 GO:0009887| organ morphogenesis TNFSF11;INSR GO:0043406| positive regulation of MAP kinase activity FLT3;TNFSF11;EGFR;ERBB2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0098609| EGFR;CDH5 GO:0006810| transport ABCB1;ABCG2 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;EGFR;PTGS2 GO:0006979| response to oxidative stress PTGS2;EGFR;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;ALK GO:0006955| immune response IGF1R;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ABL1 GO:0007275| multicellular organismal development TNFSF11;ERBB4;EGFR GO:0043065| positive regulation of apoptotic process PTGS2;ERBB4;ABL1 GO:0042327| positive regulation of phosphorylation TNFSF11;EGFR GO:0001503| ossification TNFSF11;EGFR GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0014070| response to organic cyclic compound EGFR;PTGS2 GO:0006855| drug transmembrane transport SLC47A1;SLC47A2;SLC22A1;ABCB1;ABCB5;ABCG2 GO:0008285| negative regulation of cell proliferation ERBB4;CDH5;PTGS2 GO:0030154| cell differentiation TNFSF11;FLT3;ABCB5 GO:0007613| memory PTGS2;INSR GO:0042908| xenobiotic transport ABCG2;ABCB5;ABCB1 GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 39233:[DB00480 DB02159] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02159|(R)-Propylene glycol icd;LYZ common genes common pathways GO:0006954| inflammatory response LYZ;PTGS2 39234:[DB00480 DB03866] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03866|Prostaglandin G2 PTGS2 common genes PTGS2 common pathways GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:1990776| PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0008217| regulation of blood pressure PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0055114| oxidation-reduction process PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0007568| aging PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:1902219| PTGS2 39235:[DB00480 DB01926] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01926|Carboxymycobactin S LCN2 common genes common pathways 39236:[DB00480 DB02741] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02741|CD564 RARG common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;RARG GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNFSF11 GO:1990830| TNFSF11;RARG 39237:[DB00480 DB06077] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06077|Lumateperone HTR2A;DRD2 common genes common pathways GO:0007613| memory HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2 GO:0042493| response to drug ABCB1;DRD2;HTR2A;PTGS2 39238:[DB00480 DB07215] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07215|2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID NCOA1;PPARA common genes common pathways GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NCOA1;PPARA GO:0043065| positive regulation of apoptotic process NCOA1;PTGS2 GO:0006629| lipid metabolic process PPARA;PTGS2 39239:[DB00480 DB03085] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03085|Glycolic acid G6PD;thiO common genes common pathways GO:0055114| oxidation-reduction process PTGS2;G6PD GO:0014070| response to organic cyclic compound G6PD;PTGS2 GO:0006629| lipid metabolic process G6PD;PTGS2 39240:[DB00480 DB12579] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12579|JNJ-37822681 DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0042493| response to drug DRD2;PTGS2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 39241:[DB00480 DB03773] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03773|alpha-D-quinovopyranose AMY2A;AMY2A;SLC16A7;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;SLC16A1 GO:0055085| transmembrane transport ABCB1;SLC16A1;SLC16A7 39242:[DB00480 DB07460] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07460|2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE PTK2 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PTK2 GO:0008284| positive regulation of cell proliferation PTGS2;PTK2 GO:0043066| negative regulation of apoptotic process PTK2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PTK2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PTK2 GO:0001525| angiogenesis PTK2;PTGS2 GO:0007275| multicellular organismal development PTK2;TNFSF11 39243:[DB00480 DB04564] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04564|Gluconolactone LCT common genes common pathways 39244:[DB00480 DB05116] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05116|Thymectacin TYMS common genes common pathways GO:0007568| aging PTGS2;TYMS GO:0042493| response to drug ABCB1;TYMS;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;TYMS GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS 39245:[DB00480 DB00411] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0006629| lipid metabolic process PTGS2;PLA2G4A GO:0042127| regulation of cell proliferation PTGS2;PLA2G4A GO:0007155| cell adhesion CDH5;ACHE GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 39246:[DB00480 DB00957] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0006810| transport ABCB1;ABCC2;AR GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0060749| mammary gland alveolus development AR;ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;TNFSF11;ESR1 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug ABCC2;ABCB1;PTGS2 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0038001| paracrine signaling TNFSF11;PGR GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 39247:[DB00480 DB04860] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04860|Isatoribine TLR7 common genes common pathways GO:0006955| immune response TNFSF11;TLR7 GO:0006954| inflammatory response TLR7;PTGS2 GO:0071260| cellular response to mechanical stimulus TLR7;PTGS2 39248:[DB00480 DB08228] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08228|5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one NQO2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NQO2 39249:[DB00480 DB05046] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05046|V1003 OPRK1;OPRM1 common genes common pathways GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0019233| sensory perception of pain PTGS2;OPRK1;OPRM1 GO:0006955| immune response OPRK1;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 39250:[DB00480 DB06871] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06871|17-METHYL-17-ALPHA-DIHYDROEQUILENIN ESR1;NCOA2 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TNFSF11;ESR1 39251:[DB00480 DB06901] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06901|2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL CELA2A common genes common pathways 39252:[DB00480 DB07691] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07691|2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid PPARD common genes common pathways GO:0006629| lipid metabolic process PPARD;PTGS2 GO:0007566| embryo implantation PTGS2;PPARD GO:0030154| cell differentiation TNFSF11;PPARD GO:0042127| regulation of cell proliferation PTGS2;PPARD GO:0043066| negative regulation of apoptotic process PTGS2;PPARD GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0050728| negative regulation of inflammatory response PPARD;CDH5 GO:0046697| decidualization PPARD;PTGS2 GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0010033| response to organic substance PPARD;PTGS2 39253:[DB00480 DB01214] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0045453| bone resorption ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 39254:[DB00480 DB00044] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00044|Lutropin alfa LHCGR common genes common pathways GO:0045670| regulation of osteoclast differentiation LHCGR;TNFSF11 39255:[DB00480 DB08808] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0045453| bone resorption ADRB2;TNFSF11 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0050873| brown fat cell differentiation ADRB3;PTGS2;ADRB1;ADRB2 GO:0007568| aging ADRB3;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 39256:[DB00480 DB09092] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09092|Xanthinol RPL3;NNT;GAPDH;IDH3A;OGDH;MDH2 common genes common pathways GO:0055114| oxidation-reduction process NNT;OGDH;GAPDH;IDH3A;PTGS2;MDH2 39257:[DB00480 DB07693] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07693|N-(3,5-dibromo-4-hydroxyphenyl)-2,6-dimethylbenzamide TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport TTR;ABCB1 39258:[DB00480 DB07253] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07253|N'-(5-chloro-1,3-benzodioxol-4-yl)-N-(3-methylsulfonylphenyl)pyrimidine-2,4-diamine EPHB4 common genes common pathways GO:0007275| multicellular organismal development EPHB4;TNFSF11 GO:0001525| angiogenesis PTGS2;EPHB4 GO:0007155| cell adhesion EPHB4;CDH5 39259:[DB00480 DB09290] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09290|Ramosetron HTR3A;CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 39260:[DB00480 DB06064] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06064|KAI-1455 PRKCE common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;PRKCE GO:0007155| cell adhesion CDH5;PRKCE GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;PRKCE 39261:[DB00480 DB08025] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08025|N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE MAPK10 common genes common pathways 39262:[DB00480 DB07517] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07517|3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS2 39263:[DB00480 DB08157] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08157|ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE CA1;CA2 common genes common pathways GO:0045672| positive regulation of osteoclast differentiation TNFSF11;CA2 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0045780| positive regulation of bone resorption CA2;TNFSF11 GO:0010033| response to organic substance CA2;PTGS2 GO:2001225| regulation of chloride transport ABCB1;CA2 39264:[DB00480 DB01309] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01309|Insulin Glulisine INSR common genes common pathways GO:0007613| memory INSR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 GO:0008284| positive regulation of cell proliferation INSR;PTGS2 GO:0007612| learning INSR;PTGS2 GO:0009887| organ morphogenesis TNFSF11;INSR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR 39265:[DB00480 DB00040] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways GO:0008217| regulation of blood pressure PTGS2;GCGR GO:0008284| positive regulation of cell proliferation PTGS2;GLP2R 39266:[DB00480 DB04016] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04016|2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid CTSG;CMA1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CTSG GO:0006955| immune response CTSG;TNFSF11 GO:0050727| regulation of inflammatory response CMA1;PTGS2 39267:[DB00480 DB11087] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11087|Pyrethrum extract NR1I2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TNFSF11 GO:0042908| xenobiotic transport ABCB1;NR1I2 39268:[DB00480 DB00625] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00625|Efavirenz pol;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP2C8;UGT1A1;ALB;ABCB11;SLC22A1 common genes common pathways GO:0010033| response to organic substance CYP1A2;UGT1A1;PTGS2 GO:0055085| transmembrane transport ABCB11;SLC22A1;ABCB1 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0098869| PTGS2;ALB GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006810| transport ABCB11;ABCB1 GO:0042493| response to drug PTGS2;UGT1A1;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;PTGS2;CYP3A5;CYP3A7;CYP3A4;CYP2D6;CYP2B6;CYP2C9;CYP1A2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;CYP1A2 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;CYP1A2;PTGS2 39269:[DB00480 DB01700] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01700|AICA ribonucleotide ATIC common genes common pathways 39270:[DB00480 DB05455] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05455|SR 121463 AVPR1B common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;AVPR1B 39271:[DB00480 DB03329] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03329|2-Pyridinethiol CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 39272:[DB00480 DB14034] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14034|Darglitazone PPARG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0010033| response to organic substance PTGS2;PPARG 39273:[DB00480 DB03100] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03100|6-Nitroindazole NOS2;NOS3 common genes common pathways GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 GO:0055114| oxidation-reduction process PTGS2;NOS2;NOS3 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;NOS3;CDH5 GO:0008217| regulation of blood pressure NOS3;PTGS2 39274:[DB00480 DB05959] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05959|ENMD-1198 TNFRSF11A;HIF1A;STAT3 common genes common pathways GO:0008285| negative regulation of cell proliferation STAT3;CDH5;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;STAT3 GO:0071848| positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling TNFRSF11A;TNFSF11 GO:0071812| positive regulation of fever generation by positive regulation of prostaglandin secretion TNFSF11;TNFRSF11A GO:0030154| cell differentiation HIF1A;TNFSF11 GO:0071847| TNFSF11-mediated signaling pathway TNFSF11;TNFRSF11A GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNFRSF11A GO:0006954| inflammatory response STAT3;PTGS2;TNFRSF11A GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFRSF11A;TNFSF11 GO:0009314| response to radiation PTGS2;TNFRSF11A GO:0001503| ossification TNFRSF11A;TNFSF11 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;HIF1A GO:0001525| angiogenesis HIF1A;PTGS2 GO:0007275| multicellular organismal development TNFRSF11A;TNFSF11 GO:0010033| response to organic substance STAT3;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;TNFRSF11A GO:0033209| tumor necrosis factor-mediated signaling pathway TNFRSF11A;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;STAT3 GO:0071456| cellular response to hypoxia PTGS2;HIF1A GO:0007568| aging PTGS2;STAT3 GO:0019221| cytokine-mediated signaling pathway TNFSF11;STAT3 GO:0016567| protein ubiquitination CRBN;HIF1A GO:0042493| response to drug STAT3;ABCB1;PTGS2 GO:0030316| osteoclast differentiation TNFSF11;TNFRSF11A GO:0002548| monocyte chemotaxis TNFRSF11A;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;TNFRSF11A;STAT3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;STAT3;HIF1A GO:0043066| negative regulation of apoptotic process STAT3;HIF1A;PTGS2 GO:0034097| response to cytokine stimulus TNFRSF11A;PTGS2;STAT3 GO:0060749| mammary gland alveolus development TNFRSF11A;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;HIF1A GO:0032496| response to lipopolysaccharide TNFRSF11A;PTGS2 39275:[DB00480 DB07559] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07559|(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide DHODH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHODH GO:0042493| response to drug ABCB1;DHODH;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0014070| response to organic cyclic compound DHODH;PTGS2 39276:[DB00480 DB00640] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00640|Adenosine ADORA2A;ADORA2B;ADORA3;ADORA1;ADA;ADK;SLC28A3 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;ADA;ADORA1 GO:0007155| cell adhesion ADA;CDH5 GO:0050728| negative regulation of inflammatory response ADA;ADORA2A;CDH5;ADORA1 GO:0042493| response to drug ABCB1;ADA;ADORA2A;PTGS2 GO:0097756| PTGS2;ADORA1 GO:0007568| aging ADA;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;ADORA2A GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;ADORA2B GO:0006954| inflammatory response ADORA2A;PTGS2;ADORA3;ADORA1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2 GO:0050870| positive regulation of T cell activation ADA;TNFSF11 GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;ADORA1;ADORA3;ADORA2A;PTGS2 39277:[DB00480 DB04429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04429|4'-Hydroxyflavanone SHBG common genes common pathways 39278:[DB00480 DB08692] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08692|D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acid CTRB1 common genes common pathways 39279:[DB00480 DB03962] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03962|Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate PGD common genes common pathways GO:0055114| oxidation-reduction process PTGS2;PGD 39280:[DB00480 DB06153] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0006954| inflammatory response PTGS2;HRH1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process UGT2B10;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D;CHRM3 GO:0007613| memory HRH1;HTR2A;PTGS2 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;HTR2A;ADRA1A;ADRA1D;HRH1;ADRA2C GO:0042493| response to drug HTR2C;ABCB1;HTR1B;ADRA1A;HTR2A;HTR2B;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2;HTR1A;HTR2B;ADRA2A;CHRM1;ADRA1D GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;TNFSF11;ADRA2A GO:0007568| aging PTGS2;ADRA1A;HTR2A 39281:[DB00480 DB08736] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08736|S,R-Warfarin alcohol ALB common genes common pathways GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2 39282:[DB00480 DB13152] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13152|Coagulation Factor IX Human F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F7;F10 GO:0055114| oxidation-reduction process F8;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;F2 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0010469| regulation of receptor activity TNFSF11;F2 GO:0007568| aging PTGS2;LRP1 GO:0010942| positive regulation of cell death PTGS2;LRP1 GO:0006629| lipid metabolic process LRP1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;LRP1;F2 GO:0014070| response to organic cyclic compound F7;PTGS2 39283:[DB00480 DB06533] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06533|Ragaglitazar PPARA;PPARG common genes common pathways GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0006629| lipid metabolic process PTGS2;PPARA;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0042493| response to drug ABCB1;PPARG;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA;PPARG 39284:[DB00480 DB06472] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0007155| cell adhesion ITGB3;ITGA2B;CDH5 39285:[DB00480 DB07247] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07247|[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA F7;F3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F3;TNFSF11;F7 GO:0019221| cytokine-mediated signaling pathway TNFSF11;F3 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0014070| response to organic cyclic compound F7;PTGS2 39286:[DB00480 DB07140] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07140|5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 39287:[DB00480 DB05916] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05916|CT-011 PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PDCD1 GO:0043065| positive regulation of apoptotic process PDCD1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;PDCD1 39288:[DB00480 DB07814] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07814|Gibberellic acid AADACL2 common genes common pathways 39289:[DB00480 DB01902] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01902|1-Ethyl-Pyrrolidine-2,5-Dione NSF;ERO1B common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ERO1B 39290:[DB00480 DB00060] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00060|Interferon beta-1a IFNAR1;IFNAR2 common genes common pathways GO:0032496| response to lipopolysaccharide IFNAR1;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IFNAR1 39291:[DB00480 DB02568] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02568|Peldesine PNP common genes common pathways GO:0042493| response to drug ABCB1;PNP;PTGS2 GO:0006955| immune response TNFSF11;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP 39292:[DB00480 DB00906] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes common pathways GO:0051260| protein homooligomerization SLC6A1;TNFSF11 GO:0006810| transport ABCB1;SLC6A1 GO:0032355| response to estradiol stimulus PTGS2;SLC6A1 GO:0010033| response to organic substance PTGS2;UGT1A1;SLC6A1 GO:0055085| transmembrane transport SLC6A1;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0007612| learning PTGS2;SLC6A1 GO:0010243| response to organic nitrogen PTGS2;SLC6A1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug UGT1A1;PTGS2;ABCB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;SLC6A1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39293:[DB00480 DB04495] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04495|RU81843 SRC common genes common pathways GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0070542| response to fatty acid SRC;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:1902533| TNFSF11;SRC GO:0098609| SRC;CDH5 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0007155| cell adhesion SRC;CDH5 GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0034332| adherens junction organization CDH5;SRC 39294:[DB00480 DB02271] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02271|S-(2-Oxo)Pentadecylcoa NMT2 common genes common pathways 39295:[DB00480 DB07079] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07079|3-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}propane-1-thiol ADAM17 common genes common pathways GO:0032496| response to lipopolysaccharide ADAM17;PTGS2 GO:0007155| cell adhesion ADAM17;CDH5 GO:0008284| positive regulation of cell proliferation ADAM17;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;ADAM17 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;ADAM17 39296:[DB00480 DB02838] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02838|3,4-Dihydro-2h-Pyrrolium-5-Carboxylate DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;PTGS2 39297:[DB00480 DB06750] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06750|Ginsenoside Rg1 SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3 39298:[DB00480 DB03609] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03609|3-Deoxyguanosine PNP common genes common pathways GO:0042493| response to drug PTGS2;PNP;ABCB1 GO:0006955| immune response TNFSF11;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP 39299:[DB00480 DB13949] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13949|Ferric cation TFRC;TF;ITGB3;CALR common genes common pathways GO:0010033| response to organic substance PTGS2;CALR GO:1990830| TNFSF11;TFRC GO:0045780| positive regulation of bone resorption TFRC;TNFSF11 GO:0032355| response to estradiol stimulus CALR;PTGS2 GO:0030316| osteoclast differentiation TFRC;TNFSF11 GO:0042493| response to drug ABCB1;CALR;PTGS2 GO:0007155| cell adhesion ITGB3;CDH5 GO:0008284| positive regulation of cell proliferation CALR;PTGS2 GO:0042127| regulation of cell proliferation TFRC;PTGS2 39300:[DB00480 DB08756] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08756|(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE PRKACA;PKIA;ROCK1;ROCK2 common genes common pathways GO:0034605| cellular response to heat PRKACA;PTGS2 GO:2000114| regulation of establishment of cell polarity ROCK1;ROCK2;CDH5 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA 39301:[DB00480 DB04404] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04404|Allosamizoline CHIT1 common genes common pathways GO:0006955| immune response CHIT1;TNFSF11 39302:[DB00480 DB08811] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0071260| cellular response to mechanical stimulus PDE2A;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2;PDE3A GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042493| response to drug ABCB1;PTGS2;PDE3A GO:0043066| negative regulation of apoptotic process PDE3A;PTGS2 39303:[DB00480 DB01092] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0007568| aging PTGS2;CYP1A1 GO:0055085| transmembrane transport SLC22A8;SLCO1B1;SLCO1A2;SLCO1B3;SLCO1C1;SLCO4C1;ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0055114| oxidation-reduction process PTGS2;CYP1A1 GO:0042493| response to drug ABCB1;ATP1A3;PTGS2;CYP1A1;ATP1A1 GO:0007613| memory ATP1A3;PTGS2 GO:0030154| cell differentiation TNFSF11;SLCO4C1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0008217| regulation of blood pressure ATP1A1;PTGS2;ATP1A2 GO:0007275| multicellular organismal development SLCO4C1;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1;ATP1A2 39304:[DB00480 DB07772] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07772|(1R)-1-{[(4'-methoxy-1,1'-biphenyl-4-yl)sulfonyl]amino}-2-methylpropylphosphonic acid MMP8 common genes common pathways 39305:[DB00480 DB03255] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03255|Phenol cobT;ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS2 39306:[DB00480 DB07437] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07437|1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE UPP1 common genes common pathways 39307:[DB00480 DB05125] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05125|SC12267 DHODH common genes common pathways GO:0042493| response to drug ABCB1;DHODH;PTGS2 GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0014070| response to organic cyclic compound DHODH;PTGS2 39308:[DB00480 DB04892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04892|Phenserine ACHE;BCHE;APP common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5;APP GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0007613| memory APP;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2 GO:0042493| response to drug ABCB1;BCHE;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;APP GO:0007612| learning APP;BCHE;PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;APP GO:0007155| cell adhesion APP;CDH5;ACHE GO:0051260| protein homooligomerization TNFSF11;APP GO:0006979| response to oxidative stress APP;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;PTGS2 39309:[DB00480 DB05487] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05487|Custirsen ESR1;NFKB2;NFKB1 common genes common pathways GO:0006954| inflammatory response NFKB1;NFKB2;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity NFKB2;NFKB1;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0007568| aging NFKB2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0050728| negative regulation of inflammatory response NFKB1;CDH5 GO:0032496| response to lipopolysaccharide NFKB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB2;NFKB1;ESR1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;NFKB1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0034097| response to cytokine stimulus NFKB2;PTGS2 39310:[DB00480 DB00942] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00942|Cycrimine CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 39311:[DB00480 DB02761] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02761|S-Mercaptocysteine sseA;TST;sufS common genes common pathways 39312:[DB00480 DB08201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08201|(1S)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0007612| learning BCHE;PTGS2 GO:0042493| response to drug PTGS2;BCHE;ABCB1 39313:[DB00480 DB12010] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0050728| negative regulation of inflammatory response MAPK7;TEK;CDH5;PRKCD;TYRO3 GO:0010243| response to organic nitrogen PTK2B;PTGS2;FLT3;CDK1 GO:0048661| positive regulation of smooth muscle cell proliferation MTOR;PDGFRB;IRAK1;FGFR2;EGFR;IRAK4;PTGS2;TGFBR2 GO:0007156| homophilic cell adhesion RET;CDH5 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0019221| cytokine-mediated signaling pathway IRAK4;HCK;IRAK3;FER;JAK2;KIT;CSF1R;FLT3;TNFSF11;IRAK1 GO:0051897| positive regulation of protein kinase B signaling cascade TGFBR1;FGFR2;MTOR;STK3;PDGFRB;PIK3CG;MET;TNFSF11;ERBB4;PIK3CD;INSR;FGFR3;FYN;TEK;AXL;FGFR1;KIT;MST1R;ERBB2;PTK2;LCK;SRC;EGFR;PDGFRA GO:0016567| protein ubiquitination PLK1;CRBN GO:0042493| response to drug SRC;RET;PTK2B;TGFBR2;PTGS2;CDK4;UGT1A1;ABCG2;MAP2K6;LCK;CDK1;FYN;LYN;NTRK1;ABCB1 GO:0006631| fatty acid metabolic process PRKAG1;PTGS2;PRKAG3;PRKAB2;PRKAA2;PRKAA1;PRKAG2;PRKAB1 GO:0002548| monocyte chemotaxis FLT1;TNFSF11 GO:0030316| osteoclast differentiation CSF1R;MAPK14;EPHA2;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;ALOX5;CYP3A4 GO:0034332| adherens junction organization SRC;CDH5;CSK GO:0045944| positive regulation of transcription from RNA polymerase II promoter MAPK7;BMPR2;MAPK14;RPS6KA3;BMPR1B;TBK1;FGFR2;PRKD1;TXK;RIPK2;CAMK1;TNFSF11;MET;YES1;CASK;RPS6KA1;MAP2K5;ACVR1B;STK16;EGFR;HIPK2;RIPK1;IKBKB;RAF1;ACVR1 GO:0008284| positive regulation of cell proliferation DDR2;EPHA1;ERBB4;FLT3;NTRK3;LYN;INSR;FGFR3;FGFR2;TGFBR1;MATK;CSNK2A1;PRKAA1;PDGFRB;NTRK2;TTK;HCK;FLT1;PTK2B;PDGFRA;EGFR;PAK1;HIPK2;MST1R;KIT;CSF1R;FGFR1;TGFBR2;PTGS2;CDK4;KDR;FER;FLT4;PTK2;JAK2 GO:0043066| negative regulation of apoptotic process PTGS2;AXL;LTK;DAPK1;PRKCI;CSF1R;GSK3B;PLK2;RPS6KA1;FLT4;PTK2;NUAK2;KDR;PIM1;RAF1;IKBKB;SRC;HCK;EIF2AK2;EGFR;PTK2B;HIPK3;CAMK1D;AURKA;TGFBR1;PLK1;PLK3;RPS6KA3;PRKAA2;PDGFRB;PAK2;IRAK1;PRKAA1;BRAF;MAPK7;PIM3;CDK1;ERBB4;RIPK2;MAP4K4;NTRK1;TEK GO:0007155| cell adhesion TYRO3;PTK2B;SRC;RET;HCK;DDR1;CASK;FER;NUAK1;EPHA2;EPHB4;CDH5;ABL1;EPHA1;DDR2;PRKCE;PKN2;ABL2;BMX;EPHA3;EPHB1;EPHA8;EPHA4 GO:0060749| mammary gland alveolus development ERBB4;TNFSF11;DDR1 GO:0042127| regulation of cell proliferation NUAK1;ITK;KIT;TGFBR2;FGFR1;CDK4;PTGS2;YES1;LCK;PTK2;JAK2;TYK2;SRC;TNK1;ALK;PTK2B;EGFR;ZAP70;TEC;BTK;SGK3;FGR;PTK6;TNK2;SRMS;BRAF;BMPR2;BMX;ABL2;FES;BLK;CSK;ABL1;JAK1;TXK;FYN GO:0007612| learning NTRK2;EIF2AK4;INSR;EPHB2;FYN;PAK5;PTGS2 GO:0032496| response to lipopolysaccharide MAPK14;RPS6KA3;IRAK1;FGFR2;JAK2;UGT1A1;FER;PTGS2;IRAK3 GO:0046330| positive regulation of JNK cascade TAOK2;FLT4;MINK1;RIPK1;MAP3K11;PTK2B;MAP4K2;MAP3K10;TAOK3;HIPK2;TAOK1;STK3;TNFSF11;RIPK2 GO:0009887| organ morphogenesis FGFR2;BRAF;TNFSF11;EPHB2;INSR;TGFBR2;SYK GO:0043406| positive regulation of MAP kinase activity FLT1;SRC;EGFR;FGFR1;KIT;MST1R;ERBB2;TNFSF11;FLT3;LRRK2;CSK;PDE5A;PDGFRB;PIK3CG;IRAK1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTK2B;EGFR;PTGS2;NTRK1 GO:0010033| response to organic substance PAK1;UGT1A1;TGFBR2;CDK4;PTGS2;CLK2;TEK;BTK GO:0031915| positive regulation of synaptic plasticity PTGS2;EPHB2 GO:0000086| G2/M transition of mitotic cell cycle PLK4;PRKACA;NEK2;CLASP1;CHEK2;CDK1;CIT;PKMYT1;MELK;AURKA;PLK1;LATS1;PLK3;WEE1;ABCB1 GO:0055085| transmembrane transport CSN3;ABCB1;ABCB5;ABCG2 GO:0034612| response to tumor necrosis factor RIPK1;MAP4K3;JAK2;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;TGFBR1;HIPK2;ACVR1;SRC;PTK2;TGFBR2 GO:0051260| protein homooligomerization RIPK1;IKBKE;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTK2B;EGFR;PTGS2;JAK2;INSR;MTOR GO:0006979| response to oxidative stress JAK2;PTGS2;EGFR;OXSR1;ABL1;LRRK2 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process GSK3A;GSK3B;CSNK1A1;CRBN;CDK1 GO:1902533| SRC;TNFSF11;TEK GO:0033209| tumor necrosis factor-mediated signaling pathway RIPK1;IKBKB;PTK2B;JAK2;TNFSF11 GO:0045780| positive regulation of bone resorption TNFSF11;SYK;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2;PDGFRB GO:2000114| regulation of establishment of cell polarity ROCK2;CDH5;PTK2B GO:0010469| regulation of receptor activity TNFSF11;PRKCD GO:0098609| EGFR;SRC;CDH5;PAK4 GO:0034605| cellular response to heat PRKACA;PTGS2;LYN;IRAK1 GO:0045670| regulation of osteoclast differentiation TNFSF11;MTOR GO:0071456| cellular response to hypoxia PRKCE;IRAK1;MTOR;PRKAA1;SLC29A1;SRC;HIPK2;PTGS2 GO:0007568| aging IRAK1;PDGFRB;AURKB;NTRK1;PTGS2;TGFBR2 GO:0030282| bone mineralization FGFR2;FGFR3;PTGS2 GO:0006810| transport ABCB1;ABCG2 GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11;MAP2K2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCQ;IRAK1;CAMK2A;BTK;MAP3K13;PRKD1;RIPK2;NTRK1;TNFSF11;RIPK4;FER;PRKCI;IRAK4;RIPK1;EIF2AK2;ALK;IKBKB;IRAK3 GO:0006954| inflammatory response KIT;CSF1R;JAK3;PTGS2;AXL;ADORA3;SYK;ALOX5;HCK;IKBKB;PRKCQ;PIK3CG;TBK1;BMPR1B;CAMK1D;PRKD1;RIPK2;LYN;PIK3CD;MAP2K3 GO:0010942| positive regulation of cell death RIPK2;MTOR;RIPK1;PTGS2 GO:0006955| immune response TNFSF11;IKBKE;CTSS;ZAP70;MAP4K2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity STK3;TNFSF11;DDR2;KIT;JAK2;HIPK2 GO:0071498| cellular response to fluid shear stress PTK2B;SRC;PTGS2 GO:0033598| mammary gland epithelial cell proliferation EPHA2;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process RAF1;SRC;RPS6KA1;PTGS2;MAP2K5;RPS6KA3;CSNK2A1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043065| positive regulation of apoptotic process PDGFRB;STK3;LATS1;CAMK1D;MAPK9;TGFBR1;NTRK3;RIPK2;ABL1;MELK;STK17A;ERBB4;EPHA7;JAK2;MAP2K6;CDK4;PTGS2;DAPK3;MAP3K10;MAP3K9;RIPK1;MAP3K11;SRC GO:0050727| regulation of inflammatory response LYN;STK39;PTGS2;JAK2;HCK GO:0009314| response to radiation NTRK1;PLK3;PTGS2;KIT GO:0042307| positive regulation of protein import into nucleus MAPK14;PTGS2;PRKCD GO:0042327| positive regulation of phosphorylation LYN;TNFSF11;EGFR;RIPK1 GO:0001503| ossification EGFR;DDR2;TNFSF11 GO:0006629| lipid metabolic process PRKAG3;PRKAG1;PTGS2;PRKAB1;PRKAG2;PRKAA1;PRKAA2;PRKAB2;CYP3A4 GO:0071260| cellular response to mechanical stimulus MAP3K1;CHEK1;EGFR;PTGS2;MAP3K2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4 GO:0001525| angiogenesis SYK;PTK2B;FLT1;PTK2;FLT4;KDR;PTGS2;FGFR1;EPHB2;EPHB4;EPHA2;TIE1;TEK;PRKD1;EPHA1;PIK3CG;MAPK14;EPHB1;FGFR2;TGFBR1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade MAP3K3;IRAK1;TBK1;ABL1;PRKD1;RIPK2;FYN;IKBKE;TNFSF11;PRKCE;PLK2;IRAK4;RIPK1;IKBKB GO:0007275| multicellular organismal development EPHA8;EPHA4;NTRK2;PDGFRB;DCLK1;CIT;SIK1;CAMK1;TNFSF11;ERBB4;FES;EPHB2;EPHB4;NTRK1;EPHA2;NTRK3;FYN;CSF1R;GSK3B;CDK4;ICK;CAMK2G;MUSK;KDR;MARK2;MINK1;EPHA7;PTK2;RAF1;FLT1;CAMK2B;PIM1;PAK3;TSSK1B;PDGFRA;EGFR;STK36 GO:0019233| sensory perception of pain NTRK1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;FRK;CSK;LYN;NTRK1;ERBB4;STK3;PTK2B;ADORA3;EIF2AK2;EIF2AK1;RAF1;JAK2;DDR1;CSF1R;PTGS2;TGFBR2 GO:0008217| regulation of blood pressure STK39;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;TGFBR2;UGT1A1;EGFR;PDGFRB;CDK1;LYN GO:0006855| drug transmembrane transport ABCG2;ABCB5;ABCB1 GO:0007257| activation of JUN kinase activity TNFSF11;MAP4K5;ERN1;TAOK1;MAP4K1;MAP3K6;SYK;MAP3K10;MAP4K2;MAP3K9;MAP3K11;RIPK1;PKN1;MAP3K2;TAOK2 GO:0045453| bone resorption TNFSF11;PTK2B;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN;RIOK3 GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PAK1;RAF1;PTGS2;PRKD1;RIPK2;NTRK3;CAMK1;BRAF;LATS1;NTRK2;TBK1 GO:0006633| fatty acid biosynthetic process PRKAG3;PTGS2;PRKAG1;PRKAG2;PRKAB1;PRKAA2;PRKAA1;PRKAB2 GO:0090336| positive regulation of brown fat cell differentiation MAPK14;PTGS2 GO:0050870| positive regulation of T cell activation TNFSF11;PRKCQ;LCK GO:0034644| cellular response to UV AURKB;EIF2AK4;PTGS2 GO:0070542| response to fatty acid PTGS2;SRC GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0010226| response to lithium ion PTK2B;PTGS2 GO:0019722| calcium-mediated signaling PDPK1;CAMKK2;BTK;LRRK2;TNFSF11 GO:0007566| embryo implantation PTGS2;TGFBR2;DDR1 GO:0030154| cell differentiation JAK2;MARK2;FER;KDR;MUSK;YES1;AXL;CAMK2G;TGFBR2;CDK16;GSK3B;PTK2B;CAMK2B;FLT1;RAF1;TNK1;TSSK1B;HCK;ABCB5;TYK2;DCLK1;NTRK2;BRAF;SRMS;ROS1;MAPK7;TNK2;FGR;CAMK2A;MATK;TGFBR1;TEC;BMPR1B;PIK3CD;FYN;NTRK3;TXK;EPHA2;NTRK1;JAK1;FRK;PRKD1;CSK;BLK;TNFSF11;CAMK2D;FLT3;CIT;LRRK2;CAMK1;SIK1 GO:0007613| memory PTGS2;MUSK;PLK2;PAK5;INSR GO:0042908| xenobiotic transport ABCB1;ABCB5;ABCG2 39314:[DB00480 DB04761] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04761|PYRIMIDINE-4,6-DICARBOXYLIC ACID BIS-[(PYRIDIN-3-YLMETHYL)-AMIDE] MMP13 common genes common pathways GO:0030282| bone mineralization PTGS2;MMP13 39315:[DB00480 DB08077] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08077|2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB GO:0098869| HBB;HBA1;PTGS2 GO:0010942| positive regulation of cell death PTGS2;HBA1;HBB GO:0008217| regulation of blood pressure HBB;PTGS2 39316:[DB00480 DB14533] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;HDAC4;AGT GO:0006629| lipid metabolic process CLU;APOA1;C3;PON1;PTGS2;APOBR;APOE;APOL1 GO:0001503| ossification AHSG;MMP9;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;APP GO:0042307| positive regulation of protein import into nucleus PTGS2;JUP GO:0043065| positive regulation of apoptotic process PTGS2;TP73;TP53;SOD1;KNG1;APP;CLU;MMP9 GO:0050727| regulation of inflammatory response S100A8;ESR1;PGLYRP2;AHSG;S100A9;PTGS2 GO:0019233| sensory perception of pain PTGS2;BDKRB1 GO:0007275| multicellular organismal development TNFSF11;TPI1;HRNR;TP53;F2 GO:0001525| angiogenesis S100A7;PDCD6;PTGS2;FN1 GO:0010575| positive regulation vascular endothelial growth factor production C5;C3;PTGS2 GO:0006955| immune response JCHAIN;IL3;C3;C1QC;VTN;C8B;IGHA1;C1R;C8A;IGKV1-17;IGLV3-21;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;APP;TNFSF11;JUP;HDAC4 GO:0006954| inflammatory response C3;S100A9;PTGS2;KRT16;KLKB1;S100A8;HDAC4;C5;C4B;BDKRB1;KNG1;SERPINA3 GO:0010942| positive regulation of cell death PTGS2;MT3;HBA1;HBB GO:0070371| ERK1 and ERK2 cascade AGT;TNFSF11;MT3;APOA1 GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A9;CLU;APP;INS;S100A8;TNFSF11;AGT GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;MT3;MDM2 GO:0070542| response to fatty acid PTGS2;PON1 GO:0034644| cellular response to UV TP73;TP53;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2;INS GO:0045907| positive regulation of vasoconstriction FGA;PTGS2 GO:0032463| negative regulation of protein homooligomerization CRBN;CLU GO:0030154| cell differentiation TNFSF11;KRT6A;TP53;NME1 GO:0007613| memory APP;PTGS2 GO:0019722| calcium-mediated signaling APP;TNFSF11 GO:0007566| embryo implantation MMP9;PTGS2;SOD1 GO:0051384| response to glucocorticoid stimulus CPN1;PTGS2;APOA2 GO:0008217| regulation of blood pressure SOD1;PTGS2;HBB;AGT GO:0008285| negative regulation of cell proliferation PTGS2;NME1;HDAC1;TP53;TP73;APP;HDAC4;CDH5 GO:0042633| hair cycle KRT16;PTGS2;KRT14 GO:0014070| response to organic cyclic compound MGMT;PTGS2;TP53 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0034097| response to cytokine stimulus ITIH4;PTGS2;TP53 GO:0007155| cell adhesion VTN;APP;FN1;APLP1;JUP;CDH5;IGFALS GO:0043066| negative regulation of apoptotic process MMP9;MGMT;MDM2;SOD1;HDAC1;TP53;PTGS2;MT3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HDAC4;ESR1;PARP1;APP;TP73;HDAC1;TP53 GO:0008284| positive regulation of cell proliferation AGT;HDAC4;INS;MDM2;FN1;KRT6A;HDAC1;PTGS2;IL3;F2 GO:0046330| positive regulation of JNK cascade TNFSF11;APP GO:0071318| cellular response to ATP SOD1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;HDAC1;S100A7;BDKRB1;S100A8 GO:0042127| regulation of cell proliferation PTGS2;JUP;AGT GO:0007612| learning APP;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade INS;APP;TNFSF11 GO:0019221| cytokine-mediated signaling pathway IL3;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HDAC4 GO:0019372| lipoxygenase pathway PON1;PTGS2 GO:0050728| negative regulation of inflammatory response APOA1;KRT1;APOE;CDH5 GO:0010243| response to organic nitrogen TP73;TP53;PTGS2 GO:0034332| adherens junction organization JUP;CDH5;DSP GO:0055114| oxidation-reduction process SOD1;PDIA3;PTGS2;PRDX1;P4HB;CP;CCS;ADH1C;GAPDHS GO:0006631| fatty acid metabolic process PTGS2;C3 GO:0042493| response to drug MGMT;ABCB1;MDM2;APOA2;HDAC4;NME1;PTGS2;APOA1;SOD1;TP73;TP53;HDAC1 GO:0016567| protein ubiquitination MDM2;CRBN GO:0043161| proteasomal ubiquitin-dependent protein catabolic process TP53;CRBN GO:0098869| HBA1;APOE;PTGS2;S100A9;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;INS;CLU;APP;AGT;HBB;PTGS2 GO:0006979| response to oxidative stress PTGS2;MT3;KRT1;PRDX1;SOD1;TP53;APOE;APP GO:0051260| protein homooligomerization TNFSF11;APP;GLRA1;IDE GO:0006810| transport ABCB1;TTR GO:0007568| aging GSN;AGT;KRT14;TP53;SOD1;KRT16;PTGS2 GO:0097756| PTGS2;INS GO:0071456| cellular response to hypoxia MDM2;P4HB;MT3;PTGS2;TP53 GO:0034605| cellular response to heat PTGS2;TP53;PDCD6 GO:0098609| DSP;CDH5;JUP GO:0010469| regulation of receptor activity INS;TTR;AGT;TNFSF11;F2;DAND5;IL3 GO:0032355| response to estradiol stimulus ESR1;AGT;PTGS2 GO:0010033| response to organic substance SOD1;PTGS2 GO:0009887| organ morphogenesis APLP1;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway APOA1;CDH5;PARP1 GO:0055085| transmembrane transport ABCB1;APOA1 39317:[DB00480 DB06837] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06837|(2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide ADAMTS5 common genes common pathways 39318:[DB00480 DB07962] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07962|METHYL N-[(2',4'-DIFLUORO-4-HYDROXY-5-IODOBIPHENYL-3-YL)CARBONYL]-BETA-ALANINATE TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport ABCB1;TTR 39319:[DB00480 DB03861] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03861|(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium HEXB;KCNMB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HEXB 39320:[DB00480 DB07714] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07714|6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID GSR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GSR GO:0098869| PTGS2;GSR 39321:[DB00480 DB01966] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01966|Di-Stearoyl-3-Sn-Phosphatidylethanolamine PSAP common genes common pathways GO:0006629| lipid metabolic process PSAP;PTGS2 39322:[DB00480 DB04816] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04816|Dantron ALB common genes common pathways GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB 39323:[DB00480 DB04959] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04959|HspE7 KRT7;UBR4 common genes common pathways GO:0016567| protein ubiquitination UBR4;CRBN 39324:[DB00480 DB05076] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05076|Fenretinide RBP4 common genes common pathways 39325:[DB00480 DB04846] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0007568| aging ADRB3;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;ADRB3;ADRB1;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA2C GO:0045453| bone resorption ADRB2;TNFSF11 39326:[DB00480 DB01893] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01893|N6-Benzyl Adenosine-5'-Diphosphate SRC common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug ABCB1;PTGS2;SRC GO:1902533| SRC;TNFSF11 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC 39327:[DB00480 DB08660] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08660|1,2,5,8-tetrahydroxyanthracene-9,10-dione CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0008284| positive regulation of cell proliferation CSNK2A1;PTGS2 39328:[DB00480 DB01698] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006693| prostaglandin metabolic process PTGS2;AKR1C3 GO:0010942| positive regulation of cell death PTGS2;AKR1C3 GO:0019371| cyclooxygenase pathway PTGS2;CBR1;AKR1C3 GO:0008284| positive regulation of cell proliferation PTGS2;AKR1C3 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;AKR1C3 GO:0055114| oxidation-reduction process PTGS2;CBR1;CYP2C8;AKR1C3;CYP3A4 39329:[DB00480 DB05713] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05713|LY-517717 F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 39330:[DB00480 DB00992] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00992|Methyl aminolevulinate FCGR1A common genes common pathways GO:0006955| immune response FCGR1A;TNFSF11 39331:[DB00480 DB03994] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03994|Ethanolamine ANXA3 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;ANXA3 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ANXA3;TNFSF11 39332:[DB00480 DB04400] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04400|L-erythro-7,8-dihydrobiopterin TH;PCBD1;PAH;NOS2;folB common genes common pathways GO:0009887| organ morphogenesis TH;TNFSF11 GO:0032355| response to estradiol stimulus TH;PTGS2 GO:0055114| oxidation-reduction process PTGS2;TH;NOS2;PCBD1;PAH GO:0042493| response to drug TH;PTGS2;ABCB1 GO:0006631| fatty acid metabolic process TH;PTGS2 GO:0032496| response to lipopolysaccharide NOS2;TH;PTGS2 GO:0007612| learning TH;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 GO:0014070| response to organic cyclic compound TH;PTGS2 GO:0007613| memory PTGS2;TH 39333:[DB00480 DB01791] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01791|Piclamilast PDE4A;PDE4B;PDE4C;PDE4D common genes common pathways GO:0007568| aging PDE4D;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;PDE4D 39334:[DB00480 DB00896] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 39335:[DB00480 DB04594] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04594|3-hydroxyglutaric acid HMGCL common genes common pathways GO:0006629| lipid metabolic process HMGCL;PTGS2 GO:0070542| response to fatty acid PTGS2;HMGCL 39336:[DB00480 DB00967] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes ABCB1 common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP1A2;CYP2C19;PTGS2 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0006810| transport ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP1A2;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 39337:[DB00480 DB06789] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0038001| paracrine signaling TNFSF11;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP3A5;CYP3A4 39338:[DB00480 DB03645] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03645|Phosphonoacetohydroxamic Acid ENO3 common genes common pathways GO:0042493| response to drug PTGS2;ENO3;ABCB1 GO:0007568| aging PTGS2;ENO3 39339:[DB00480 DB02581] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02581|5-[2,3-Dichloro-4-(5-{1-[2-(2-Guanidino-4-Methyl-Pentanoylamino)-Acetyl]-Piperidin-4-Yl}-1-Methyl-1h-Pyrazol-3-Yl)-Phenoxymethyl]-Furan-2-Carboxylic Acid IL2 common genes common pathways GO:0050728| negative regulation of inflammatory response CDH5;IL2 GO:0007155| cell adhesion IL2;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;IL2 GO:0008284| positive regulation of cell proliferation IL2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL2 GO:0010469| regulation of receptor activity IL2;TNFSF11 GO:0006955| immune response IL2;TNFSF11 39340:[DB00480 DB00584] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0008217| regulation of blood pressure PTGS2;ACE GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLC22A6;SLC22A8;SLC22A7;SLCO1A2;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0042493| response to drug PTGS2;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:1901529| ABCB1 39341:[DB00480 DB00485] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport SLC15A2;ABCB1;SLC15A1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39342:[DB00480 DB06599] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06599|Lexatumumab TNFRSF10B common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;TNFRSF10B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFRSF10B;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;TNFRSF10B GO:0006954| inflammatory response PTGS2;TNFRSF10B GO:0006955| immune response TNFRSF10B;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process TNFRSF10B;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;TNFRSF10B GO:0042127| regulation of cell proliferation PTGS2;TNFRSF10B GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNFRSF10B 39343:[DB00480 DB05552] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05552|TG100-115 PIK3CD;PIK3CG common genes common pathways GO:0006954| inflammatory response PTGS2;PIK3CG;PIK3CD GO:0001525| angiogenesis PTGS2;PIK3CG GO:0030154| cell differentiation TNFSF11;PIK3CD GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CD;TNFSF11;PIK3CG GO:0043406| positive regulation of MAP kinase activity PIK3CG;TNFSF11 39344:[DB00480 DB07224] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07224|N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ALANINE CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 39345:[DB00480 DB07148] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07148|(6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one PREP common genes common pathways 39346:[DB00480 DB03132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03132|3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid TPI1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;TPI1 39347:[DB00480 DB05471] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05471|SGN-30 NFKB1;NFKB2 common genes common pathways GO:0006954| inflammatory response NFKB1;PTGS2;NFKB2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;NFKB1;NFKB2 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0007568| aging NFKB2;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;NFKB1 GO:0032496| response to lipopolysaccharide PTGS2;NFKB2 GO:0043066| negative regulation of apoptotic process NFKB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;NFKB2;TNFSF11 GO:0034097| response to cytokine stimulus NFKB2;PTGS2 39348:[DB00480 DB06870] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06870|17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA-4,9,11-TRIEN-3-ONE AR common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 39349:[DB00480 DB07395] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07395|4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid PYGL common genes common pathways 39350:[DB00480 DB08119] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08119|1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE) CTRB1 common genes common pathways 39351:[DB00480 DB07072] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07072|(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 39352:[DB00480 DB01640] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01640|(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One PDE3B common genes common pathways GO:0001525| angiogenesis PDE3B;PTGS2 39353:[DB00480 DB02762] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02762|RU79072 SRC common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| SRC;CDH5 GO:1902533| SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 39354:[DB00480 DB07494] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07494|(3-EXO)-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8,8-DIMETHYL-8-AZONIABICYCLO[3.2.1]OCTANE CHRFAM7A common genes common pathways 39355:[DB00480 DB00520] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes ABCB1 common pathways GO:1901529| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:2001225| regulation of chloride transport ABCB1 GO:0051260| protein homooligomerization TNFSF11;SLC22A1;SLC22A6 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A1;SLCO1B3;SLC22A6;SLCO1B1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 39356:[DB00480 DB02988] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02988|Imino-Tryptophan DAO common genes common pathways GO:0055114| oxidation-reduction process DAO;PTGS2 39357:[DB00480 DB05708] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP1A2;CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0007613| memory PTGS2;CHRNA7 GO:0006629| lipid metabolic process CYP1A2;PTGS2 39358:[DB00480 DB08843] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08843|GS 0573 SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 39359:[DB00480 DB00383] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 39360:[DB00480 DB07613] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07613|3-phenyl-5-(1H-pyrazol-3-yl)isoxazole HPGDS common genes common pathways GO:0006631| fatty acid metabolic process HPGDS;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0019371| cyclooxygenase pathway PTGS2;HPGDS GO:0006629| lipid metabolic process PTGS2;HPGDS GO:0006693| prostaglandin metabolic process HPGDS;PTGS2 39361:[DB00480 DB07261] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07261|THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 39362:[DB00480 DB06849] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06849|1-[1'-(3-phenylacryloyl)spiro[1-benzofuran-3,4'-piperidin]-5-yl]methanamine TPSAB1 common genes common pathways 39363:[DB00480 DB00616] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00616|Candoxatril MME;ACE common genes common pathways GO:0008217| regulation of blood pressure ACE;PTGS2 GO:0019233| sensory perception of pain MME;PTGS2 39364:[DB00480 DB08960] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08960|Hexamethonium CHRNA2 common genes common pathways 39365:[DB00480 DB06147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06147|Sulfathiazole CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP19A1 39366:[DB00480 DB02950] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02950|Hymenialdisine CDK5;CDK1;CDK2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CDK1 GO:0007275| multicellular organismal development TNFSF11;CDK2 GO:0019233| sensory perception of pain PTGS2;CDK5 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;CDK1 GO:0010033| response to organic substance PTGS2;CDK2 GO:0000086| G2/M transition of mitotic cell cycle CDK1;ABCB1;CDK2 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2 GO:0045786| negative regulation of cell cycle CDK5;PTGS2 GO:0043066| negative regulation of apoptotic process CDK1;PTGS2 GO:0010243| response to organic nitrogen CDK1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CDK1 39367:[DB00480 DB06716] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;ALPL GO:0033280| response to vitamin D ALPL;PTGS2 GO:0098869| ALB;PTGS2 GO:0006810| transport GABRB2;GABRB3;ABCB1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;ALPL 39368:[DB00480 DB01662] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01662|Trans-O-Hydroxy-Alpha-Methyl Cinnamate CTRB1 common genes common pathways 39369:[DB00480 DB07350] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07350|(2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide HDAC8 common genes common pathways 39370:[DB00480 DB07849] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07849|S-NONYL-CYSTEINE GSTP1 common genes common pathways GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;GSTP1 GO:0098869| GSTP1;PTGS2 39371:[DB00480 DB11855] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0006810| transport ABCB1;ABCG2 GO:0098869| PTGS2;ALB GO:0055085| transmembrane transport ABCB1;SLCO1B3;ABCG2;SLCO1B1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:1901529| ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ABCG2;ABCB1 39372:[DB00480 DB12515] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12515|9-aminocamptothecin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39373:[DB00480 DB03297] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03297|Benzylsulfinic Acid HPN;SOD2;CMA1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;HPN GO:0055114| oxidation-reduction process SOD2;PTGS2 GO:0008217| regulation of blood pressure PTGS2;SOD2 GO:0008285| negative regulation of cell proliferation CDH5;SOD2;PTGS2 GO:0050727| regulation of inflammatory response CMA1;PTGS2 39374:[DB00480 DB01497] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways GO:0016567| protein ubiquitination CRBN;TRIM13 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;POMC GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process TRIM13;CRBN GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0032355| response to estradiol stimulus PTGS2;OPRL1 GO:0010469| regulation of receptor activity TNFSF11;POMC GO:0051092| positive regulation of NF-kappaB transcription factor activity TRIM13;TNFSF11 GO:0010942| positive regulation of cell death TRIM13;PTGS2 GO:0006955| immune response OPRD1;OPRK1;TNFSF11 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TRIM13 GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRM1;OPRK1;OPRL1 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0008217| regulation of blood pressure POMC;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 39375:[DB00480 DB00264] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes ABCB1 common pathways GO:0045453| bone resorption TNFSF11;ADRB2 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB2 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport SLC22A2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:1901529| ABCB1 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2;CYP2C19 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 39376:[DB00480 DB07007] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07007|(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0055114| oxidation-reduction process NOS2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 39377:[DB00480 DB09536] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09536|Titanium dioxide MARCO common genes common pathways 39378:[DB00480 DB03531] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03531|Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone DAO common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DAO 39379:[DB00480 DB05253] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05253|Proellex PGR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11 GO:0038001| paracrine signaling TNFSF11;PGR 39380:[DB00480 DB04418] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04418|Adenylosuccinic Acid ADSSL1 common genes common pathways 39381:[DB00480 DB00523] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes ABCB1 common pathways GO:0034097| response to cytokine stimulus PTGS2;RARA GO:0008284| positive regulation of cell proliferation PTGS2;RARA;RARG;RARB GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARA;RARG;RXRG;RXRA;RARB;TNFSF11;RXRB GO:0043066| negative regulation of apoptotic process RARG;PTGS2;RARA;RARB GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP26C1 GO:0042493| response to drug PTGS2;ABCB1 GO:0006810| transport ABCB1 GO:0032355| response to estradiol stimulus RARA;PTGS2 GO:1990830| TNFSF11;RARG GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0043065| positive regulation of apoptotic process PTGS2;RARG;IGFBP3;RARB GO:0007275| multicellular organismal development CRABP1;TNFSF11 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0007566| embryo implantation PTGS2;RXRA GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008285| negative regulation of cell proliferation RARB;CDH5;PTGS2;RARA;IGFBP3;RARG GO:0006855| drug transmembrane transport ABCB1 39382:[DB00480 DB00259] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2E1;CYP2C19;PTGS2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 39383:[DB00480 DB00306] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0019233| sensory perception of pain CHRNA4;PTGS2 GO:0007613| memory CHRNA7;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0042493| response to drug GABRG3;ABCB1;PTGS2 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0006810| transport GABRB1;GABRA6;GRIK2;GABRA4;GABRD;GABRA5;GABRA3;GABRB2;GABRG2;ABCB1;GABRA1;GABRB3 GO:0055085| transmembrane transport GRIK2;ABCB1 39384:[DB00480 DB00288] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0098609| CDH5;ANXA1 GO:0032355| response to estradiol stimulus PTGS2;ANXA1 GO:0043066| negative regulation of apoptotic process ANXA1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 GO:0042127| regulation of cell proliferation ANXA1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;ANXA1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0002548| monocyte chemotaxis TNFSF11;ANXA1 GO:0051384| response to glucocorticoid stimulus PTGS2;ANXA1 GO:0014070| response to organic cyclic compound PTGS2;ANXA1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;ANXA1 GO:0050727| regulation of inflammatory response PTGS2;ANXA1 GO:0043065| positive regulation of apoptotic process ANXA1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006954| inflammatory response PTGS2;ANXA1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;PTGS2 39385:[DB00480 DB03623] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03623|9-(4-Hydroxyphenyl)-2,7-Phenanthroline MAPK10 common genes common pathways 39386:[DB00480 DB08674] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08674|(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE FNTA;FNTB common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FNTA GO:0042127| regulation of cell proliferation FNTB;PTGS2 39387:[DB00480 DB00156] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00156|L-Threonine THNSL1;TARS;TARS2;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 39388:[DB00480 DB03095] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03095|Tetramethylammonium Ion GALE common genes common pathways 39389:[DB00480 DB04975] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0007568| aging PTGS2;CYP1A1 GO:0055114| oxidation-reduction process PTGS2;CYP1A1;CYP3A4;CYP2B6 GO:0042493| response to drug CYP1A1;PTGS2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 39390:[DB00480 DB13503] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13503|Tyrothricin ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 39391:[DB00480 DB09279] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09279|Fimasartan AGTR1 common genes common pathways GO:0042127| regulation of cell proliferation AGTR1;PTGS2 GO:0019722| calcium-mediated signaling AGTR1;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 39392:[DB00480 DB03124] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03124|5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid CASP3 common genes common pathways GO:0042493| response to drug ABCB1;CASP3;PTGS2 GO:0045786| negative regulation of cell cycle CASP3;PTGS2 GO:0043066| negative regulation of apoptotic process CASP3;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CASP3 GO:0010033| response to organic substance CASP3;PTGS2 GO:0034612| response to tumor necrosis factor CASP3;PTGS2 GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;CASP3 GO:0014070| response to organic cyclic compound PTGS2;CASP3 GO:0051384| response to glucocorticoid stimulus CASP3;PTGS2 39393:[DB00480 DB00636] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0006631| fatty acid metabolic process PPARA;CYP4A11;PTGS2 GO:0042493| response to drug PTGS2;CYP2E1;CYP1A1;ABCB1 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP2B6;PTGS2;CYP2E1;CYP4A11;CYP1A1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;TNFSF11 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0007568| aging PTGS2;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;PPARA;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 39394:[DB00480 DB08626] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08626|Thiorphan MME common genes common pathways GO:0019233| sensory perception of pain PTGS2;MME 39395:[DB00480 DB05115] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05115|NN344 INSR common genes common pathways GO:0009887| organ morphogenesis INSR;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 GO:0007612| learning PTGS2;INSR GO:0008284| positive regulation of cell proliferation INSR;PTGS2 GO:0007613| memory PTGS2;INSR 39396:[DB00480 DB08345] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08345|4-(2-(1H-IMIDAZOL-4-YL)ETHYLAMINO)-2-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 39397:[DB00480 DB06042] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0000086| G2/M transition of mitotic cell cycle ABCB1;TUBB4A;TUBB 39398:[DB00480 DB14724] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14724|Emapalumab IFNG common genes common pathways GO:0006955| immune response TNFSF11;IFNG GO:0045672| positive regulation of osteoclast differentiation IFNG;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;IFNG GO:0010469| regulation of receptor activity TNFSF11;IFNG GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;IFNG 39399:[DB00480 DB01832] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01832|4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid FAH common genes common pathways 39400:[DB00480 DB03425] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03425|2s,4r-4-Methylglutamate GRIK2 common genes common pathways GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0006810| transport ABCB1;GRIK2 39401:[DB00480 DB08060] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08060|4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID AGXT common genes common pathways GO:0051384| response to glucocorticoid stimulus AGXT;PTGS2 39402:[DB00480 DB05264] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05264|NPI 32101 CSF2RB common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CSF2RB GO:0019221| cytokine-mediated signaling pathway TNFSF11;CSF2RB 39403:[DB00480 DB01742] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01742|(3r)-1-Acetyl-3-Methylpiperidine PPIA common genes common pathways 39404:[DB00480 DB00750] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00750|Prilocaine SCN5A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN5A 39405:[DB00480 DB05849] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05849|NCX 950 ADRB2 common genes common pathways GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 39406:[DB00480 DB03470] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03470|Trypanothione TPR common genes common pathways GO:0034605| cellular response to heat TPR;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2;TPR 39407:[DB00480 DB02541] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02541|4-Hydroxybutan-1-Aminium PRSS3 common genes common pathways 39408:[DB00480 DB08510] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08510|5-ALPHA-PREGNANE-3-BETA-OL-HEMISUCCINATE IGHG2 common genes common pathways 39409:[DB00480 DB04445] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0006629| lipid metabolic process SULT2A1;PTGS2 39410:[DB00480 DB07964] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07964|(3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0033209| tumor necrosis factor-mediated signaling pathway ADAM17;TNFSF11 GO:0042493| response to drug ABCB1;ADAM17;PTGS2 GO:0032496| response to lipopolysaccharide ADAM17;PTGS2 GO:0007155| cell adhesion CDH5;ADAM17 GO:0008284| positive regulation of cell proliferation ADAM17;PTGS2 39411:[DB00480 DB04133] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04133|Degraded Cephaloridine SLC22A5;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0055085| transmembrane transport SLC22A5;SLC22A8;SLC22A6;SLC22A11;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 39412:[DB00480 DB04934] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39413:[DB00480 DB00751] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes ABCB1 common pathways GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2B6;CYP2D6;CYP3A4 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ADRA1A;HTR2A;ABCB1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:1901529| ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A;ADRA2A GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2A GO:0006810| transport ABCB1 GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0006955| immune response TNFSF11;HRH2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0007613| memory HRH1;PTGS2;HRH2;HTR2A GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A;HRH2;HTR2A;HRH1 39414:[DB00480 DB01537] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01537|4-Bromo-2,5-dimethoxyphenethylamine HTR2C;HTR2A common genes common pathways GO:0042493| response to drug HTR2C;ABCB1;HTR2A;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging PTGS2;HTR2A GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A 39415:[DB00480 DB03666] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03666|3'-Azido-3'-Deoxythymidine-5'-Monophosphate DTYMK;tmk common genes common pathways 39416:[DB00480 DB09232] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09232|Cilnidipine CACNA1B;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0006810| transport CACNB1;CACNB3;CACNB4;CACNA1B;ABCB1 GO:0055085| transmembrane transport CACNA1F;ABCB1;CACNA1B;CACNA1S;CACNA1C;CACNA1D GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0008217| regulation of blood pressure CACNA1B;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39417:[DB00480 DB00621] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00621|Oxandrolone AR;CYP2C9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0006810| transport AR;ABCB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 39418:[DB00480 DB08972] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08972|Flumequine CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 39419:[DB00480 DB00765] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00765|Metyrosine TH common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;TH GO:0007613| memory TH;PTGS2 GO:0042493| response to drug PTGS2;TH;ABCB1 GO:0006631| fatty acid metabolic process PTGS2;TH GO:0055114| oxidation-reduction process PTGS2;TH GO:0032496| response to lipopolysaccharide TH;PTGS2 GO:0007612| learning PTGS2;TH GO:0009887| organ morphogenesis TH;TNFSF11 GO:0032355| response to estradiol stimulus TH;PTGS2 39420:[DB00480 DB05824] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05824|CNS-5161 GRIN1 common genes common pathways GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0019233| sensory perception of pain GRIN1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;GRIN1 GO:0007613| memory GRIN1;PTGS2 GO:0019722| calcium-mediated signaling GRIN1;TNFSF11 GO:0007612| learning PTGS2;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 39421:[DB00480 DB03988] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03988|2,6-Diamino-Hexanoic Acid Amide ADCYAP1 common genes common pathways GO:0019233| sensory perception of pain ADCYAP1;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADCYAP1;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;ADCYAP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADCYAP1;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;ADCYAP1 GO:0045786| negative regulation of cell cycle ADCYAP1;PTGS2 39422:[DB00480 DB00805] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0007612| learning PTGS2;DRD1 GO:0007155| cell adhesion ACHE;CDH5 GO:0008284| positive regulation of cell proliferation CHRM1;HTR2A;HTR2B;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0055114| oxidation-reduction process CYP2D6;MAOA;PTGS2 GO:0042493| response to drug SLC6A4;ABCB1;HTR2C;PTGS2;HTR2B;HTR2A;DRD1;DRD2 GO:0007568| aging PTGS2;HTR2A GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0055085| transmembrane transport SLC6A4;ABCB1 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A;HTR2B GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0007613| memory SLC6A4;HTR2A;DRD1;PTGS2 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 39423:[DB00480 DB11793] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11793|Niraparib PARP1;PARP2;GUSB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 39424:[DB00480 DB03316] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03316|1,4-Diethylene Dioxide TNFSF13B;EPN1;TGFB3 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;TNFSF13B GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TGFB3 GO:0007568| aging TGFB3;PTGS2 GO:0010469| regulation of receptor activity TNFSF13B;TGFB3;TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNFSF13B GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;TGFB3 GO:0043065| positive regulation of apoptotic process TGFB3;PTGS2 GO:0006955| immune response TNFSF13B;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;TGFB3;CDH5 39425:[DB00480 DB06201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06201|Rufinamide GRM5;SCN9A;CES1;CYP2E1;CYP3A4;ALB common genes common pathways GO:0006954| inflammatory response SCN9A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0019233| sensory perception of pain SCN9A;PTGS2 GO:0055085| transmembrane transport ABCB1;SCN9A GO:0098869| PTGS2;ALB GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP3A4 GO:0042493| response to drug ABCB1;PTGS2;CYP2E1 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0007612| learning PTGS2;GRM5 39426:[DB00480 DB06185] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06185|Forodesine PNP common genes common pathways GO:0006955| immune response PNP;TNFSF11 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0042493| response to drug ABCB1;PNP;PTGS2 39427:[DB00480 DB01445] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01445|Bufotenine MAOA;MAOB common genes common pathways GO:0042493| response to drug MAOB;PTGS2;ABCB1 GO:0055114| oxidation-reduction process MAOB;MAOA;PTGS2 GO:0032496| response to lipopolysaccharide MAOB;PTGS2 39428:[DB00480 DB00374] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PPARD;CYP2C9 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0007566| embryo implantation PTGS2;PPARD GO:0071318| cellular response to ATP PTGS2;P2RY12 GO:0032496| response to lipopolysaccharide PTGS2;PTGIR GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;PPARD GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0050728| negative regulation of inflammatory response CDH5;PPARD GO:0046697| decidualization PTGS2;PPARD GO:0071456| cellular response to hypoxia PTGS2;PPARD GO:0010033| response to organic substance PPARD;PTGS2 39429:[DB00480 DB08445] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08445|(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 39430:[DB00480 DB05875] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05875|substance P CYP19A1;BCHE;PTGS2 common genes PTGS2 common pathways GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0042493| response to drug PTGS2;BCHE;ABCB1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP19A1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:1902219| PTGS2 GO:0007568| aging PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0006954| inflammatory response PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0008217| regulation of blood pressure PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 39431:[DB00480 DB06989] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06989|{4-[2-BENZYL-3-METHOXY-2-(METHOXYCARBONYL)-3-OXOPROPYL]PHENYL}SULFAMIC ACID PTPRB common genes common pathways GO:0001525| angiogenesis PTPRB;PTGS2 39432:[DB00480 DB04880] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04880|Enoximone PDE3A common genes common pathways GO:0043066| negative regulation of apoptotic process PDE3A;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;PDE3A GO:0006629| lipid metabolic process PDE3A;PTGS2 39433:[DB00480 DB08801] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08801|Dimetindene HRH1;CHRM2 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 39434:[DB00480 DB00947] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;UGT1A1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 39435:[DB00480 DB00382] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00382|Tacrine ACHE;BCHE;CES1;CYP1A2;ABCB1 common genes ABCB1 common pathways GO:0006810| transport ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0007155| cell adhesion ACHE;CDH5 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0007612| learning PTGS2;BCHE GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug BCHE;CYP1A2;ABCB1;PTGS2 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 39436:[DB00480 DB06932] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06932|10,11-dimethoxy-4-methyldibenzo[c,f]-2,7-naphthyridine-3,6-diamine PDPK1 common genes common pathways GO:0019722| calcium-mediated signaling PDPK1;TNFSF11 39437:[DB00480 DB07724] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07724|Indeglitazar NCOA1;PPARA;PPARD;PPARG common genes common pathways GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0043066| negative regulation of apoptotic process PPARD;PTGS2 GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA1;TNFSF11;PPARG;PPARA GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA;PPARD GO:0046697| decidualization PPARD;PTGS2 GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG;PPARD GO:0006629| lipid metabolic process PPARG;PPARD;PPARA;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;NCOA1;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0030154| cell differentiation TNFSF11;PPARD GO:0007566| embryo implantation PPARD;PTGS2 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 39438:[DB00480 DB01762] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01762|Acetoacetic Acid FAH;SLC16A7;SLC16A1;SLC16A3;SLC5A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A7;SLC16A1;SLC16A3;SLC5A8 GO:0006629| lipid metabolic process SLC16A1;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;SLC5A8 39439:[DB00480 DB02089] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02089|CP-526423 PYGL common genes common pathways 39440:[DB00480 DB01134] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39441:[DB00480 DB00527] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00527|Cinchocaine SCN10A;SCN5A;CALM1;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0019233| sensory perception of pain PTGS2;SCN10A GO:0055085| transmembrane transport ABCB1;CALM1;SCN5A;SCN10A GO:0042493| response to drug PTGS2;ABCB1;BCHE GO:0007612| learning PTGS2;BCHE 39442:[DB00480 DB00253] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39443:[DB00480 DB05386] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05386|recombinant human GM-CSF CSF2RA;CSF2RA;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;BCHE GO:0019221| cytokine-mediated signaling pathway CSF2RA;TNFSF11 GO:0007612| learning PTGS2;BCHE 39444:[DB00480 DB03430] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03430|(2s)-Hydroxy(4-Hydroxyphenyl)Ethanenitrile LCTL common genes common pathways 39445:[DB00480 DB07294] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07294|3-fluoro-4-[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-naphtalen-2-yl)-acetylamino]-benzoic acid RARG common genes common pathways GO:0008285| negative regulation of cell proliferation RARG;PTGS2;CDH5 GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:1990830| RARG;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;RARG 39446:[DB00480 DB05429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05429|CAT-213 CCL11 common genes common pathways GO:0006955| immune response CCL11;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;CCL11 GO:0006954| inflammatory response CCL11;PTGS2 GO:0009314| response to radiation PTGS2;CCL11 GO:0010469| regulation of receptor activity CCL11;TNFSF11 GO:0002548| monocyte chemotaxis TNFSF11;CCL11 GO:0007155| cell adhesion CDH5;CCL11 39447:[DB00480 DB07689] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07689|METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL]AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHRS4L1 39448:[DB00480 DB06127] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06127|Bisegliptin DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 39449:[DB00480 DB07574] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07574|2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE STMN4;TUBB2B;TUBA1A;TUBA1C;TUBA1B common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBA1A;ABCB1 39450:[DB00480 DB09051] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09051|Elosulfase alfa GALNS common genes common pathways 39451:[DB00480 DB06781] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39452:[DB00480 DB01615] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01615|Aceprometazine HRH1 common genes common pathways GO:0007613| memory PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 39453:[DB00480 DB02800] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02800|5-Hydroxymethylene-6-Hydrofolic Acid SHMT1 common genes common pathways GO:1990830| SHMT1;TNFSF11 39454:[DB00480 DB04931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04931|Afamelanotide MC1R common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MC1R;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;MC1R GO:0007275| multicellular organismal development MC1R;TNFSF11 39455:[DB00480 DB09151] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09151|Flutemetamol (18F) APP common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0007613| memory PTGS2;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;APP GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;APP GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0043065| positive regulation of apoptotic process APP;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;PTGS2 GO:0006979| response to oxidative stress APP;PTGS2 GO:0051260| protein homooligomerization TNFSF11;APP GO:0007612| learning PTGS2;APP GO:0046330| positive regulation of JNK cascade APP;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;TNFSF11 GO:0007155| cell adhesion CDH5;APP GO:0051897| positive regulation of protein kinase B signaling cascade APP;TNFSF11 39456:[DB00480 DB05945] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05945|MDX-1303 ANTXR2;ANTXR1 common genes common pathways 39457:[DB00480 DB07815] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07815|GIBBERELLIN A4 AADACL2 common genes common pathways 39458:[DB00480 DB11131] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11131|Capsicum oleoresin TRPV1 common genes common pathways GO:0055085| transmembrane transport TRPV1;ABCB1 GO:0034605| cellular response to heat PTGS2;TRPV1 GO:0006810| transport TRPV1;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TRPV1 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0071318| cellular response to ATP PTGS2;TRPV1 GO:0006954| inflammatory response PTGS2;TRPV1 GO:0019233| sensory perception of pain PTGS2;TRPV1 GO:0043065| positive regulation of apoptotic process TRPV1;PTGS2 GO:0006629| lipid metabolic process PTGS2;TRPV1 39459:[DB00480 DB03478] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03478|2'-O-Acetyl Adenosine-5-Diphosphoribose SIRT5 common genes common pathways 39460:[DB00480 DB01481] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01481|1-Testosterone AR common genes common pathways GO:0006810| transport AR;ABCB1 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 39461:[DB00480 DB01892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;ALOX5;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2 GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug PTGS2;ABCC2;ABCB1 GO:0055114| oxidation-reduction process ALOX5;PTGS1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0006979| response to oxidative stress ABCC2;PTGS2;PTGS1 GO:0006810| transport ABCB1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLCO1B1 39462:[DB00480 DB01141] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01141|Micafungin COMT;ARSA common genes common pathways GO:0042493| response to drug ABCB1;COMT;PTGS2 GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0007612| learning COMT;PTGS2 GO:0014070| response to organic cyclic compound COMT;PTGS2 39463:[DB00480 DB07183] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07183|N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide KDR common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process KDR;PTGS2 GO:0001525| angiogenesis PTGS2;KDR GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0030154| cell differentiation TNFSF11;KDR 39464:[DB00480 DB06804] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06804|Nonoxynol-9 PTGS2 common genes PTGS2 common pathways GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0071318| cellular response to ATP PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 39465:[DB00480 DB08678] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08678|(4-ETHYLPHENYL)SULFAMIC ACID PTPRB common genes common pathways GO:0001525| angiogenesis PTGS2;PTPRB 39466:[DB00480 DB00969] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00969|Alosetron HTR3A;CYP2C9;CYP3A4;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP3A4;CYP2C9;CYP1A2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;CYP1A2;CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 39467:[DB00480 DB12131] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12131|Vinpocetine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39468:[DB00480 DB00826] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00826|Natamycin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 39469:[DB00480 DB04820] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;COMT GO:0042493| response to drug PTGS2;MAOB;ABCB1;COMT GO:0055114| oxidation-reduction process MAOA;PTGS2;MAOB GO:0032496| response to lipopolysaccharide PTGS2;MAOB;COMT GO:0007612| learning PTGS2;COMT 39470:[DB00480 DB06515] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06515|Resiniferatoxin TRPV1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process TRPV1;PTGS2 GO:0006810| transport TRPV1;ABCB1 GO:0034605| cellular response to heat TRPV1;PTGS2 GO:0055085| transmembrane transport TRPV1;ABCB1 GO:0071318| cellular response to ATP PTGS2;TRPV1 GO:0010243| response to organic nitrogen PTGS2;TRPV1 GO:0006629| lipid metabolic process TRPV1;PTGS2 GO:0043065| positive regulation of apoptotic process TRPV1;PTGS2 GO:0019233| sensory perception of pain TRPV1;PTGS2 GO:0006954| inflammatory response PTGS2;TRPV1 39471:[DB00480 DB07182] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07182|(2S)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-[(S)-HYDROXY(3-PHENYLPROPYL)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 39472:[DB00480 DB02008] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02008|1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine PCK1 common genes common pathways GO:0032496| response to lipopolysaccharide PCK1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;PCK1 GO:0007568| aging PCK1;PTGS2 GO:0006629| lipid metabolic process PCK1;PTGS2 39473:[DB00480 DB07537] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07537|N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide KDR common genes common pathways GO:0001525| angiogenesis KDR;PTGS2 GO:0007275| multicellular organismal development TNFSF11;KDR GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0030154| cell differentiation KDR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process PTGS2;KDR 39474:[DB00480 DB07486] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07486|3-({4-[(1E)-3-morpholin-4-yl-3-oxoprop-1-en-1-yl]-2,3-bis(trifluoromethyl)phenyl}sulfanyl)aniline ITGAL common genes common pathways GO:0006954| inflammatory response ITGAL;PTGS2 GO:0007155| cell adhesion CDH5;ITGAL GO:0098609| ITGAL;CDH5 39475:[DB00480 DB13346] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes PTGS2 common pathways GO:0019233| sensory perception of pain PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:1990776| PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0034097| response to cytokine stimulus PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0009750| response to fructose stimulus PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0034605| cellular response to heat PTGS2 GO:1902219| PTGS2 GO:0010469| regulation of receptor activity HDAC6;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PTGS2;HDAC6 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 39476:[DB00480 DB08129] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08129|(1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol PNMT common genes common pathways 39477:[DB00480 DB00099] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00099|Filgrastim CSF3R;ELANE common genes common pathways GO:0043406| positive regulation of MAP kinase activity ELANE;TNFSF11 GO:0007155| cell adhesion CSF3R;CDH5 GO:0032496| response to lipopolysaccharide PTGS2;ELANE GO:0048661| positive regulation of smooth muscle cell proliferation ELANE;PTGS2 GO:0050728| negative regulation of inflammatory response ELANE;CDH5 GO:0019221| cytokine-mediated signaling pathway TNFSF11;CSF3R 39478:[DB00480 DB11742] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11742|Ebastine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39479:[DB00480 DB06742] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06742|Ambroxol CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39480:[DB00480 DB04326] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04326|Dihydroxyacetone phosphate ALDOA;TPI1;ALDOB;fucA common genes common pathways GO:0007275| multicellular organismal development TNFSF11;TPI1 39481:[DB00480 DB02216] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02216|S-Methylcysteine CTSD;MGMT;FABP1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process FABP1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;MGMT GO:0043066| negative regulation of apoptotic process PTGS2;FABP1;MGMT GO:0042493| response to drug PTGS2;MGMT;ABCB1 GO:0071456| cellular response to hypoxia FABP1;PTGS2 GO:0098869| FABP1;PTGS2 39482:[DB00480 DB03546] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways GO:0010033| response to organic substance PTGS2;GART 39483:[DB00480 DB06218] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 GO:0019233| sensory perception of pain SCN10A;PTGS2;SCN9A GO:0006954| inflammatory response SCN9A;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP2C19;PTGS2 GO:0055085| transmembrane transport ABCB1;SCN9A;SCN3A;SCN10A 39484:[DB00480 DB00287] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00287|Travoprost PTGFR common genes common pathways GO:0032496| response to lipopolysaccharide PTGFR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGFR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGFR;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;PTGFR 39485:[DB00480 DB01006] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP19A1;CYP2A6;CYP3A4;PTGS2 39486:[DB00480 DB01378] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01378|Magnesium cation ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0042493| response to drug PTGS2;ATP1A1;ABCB1 39487:[DB00480 DB13931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways GO:2000114| regulation of establishment of cell polarity CDH5;ROCK2;ROCK1 39488:[DB00480 DB04837] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04837|Clofedanol HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0007613| memory PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 39489:[DB00480 DB05161] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05161|Elafin ELANE;PRTN3;MPO common genes common pathways GO:0007568| aging MPO;PTGS2 GO:0006979| response to oxidative stress MPO;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ELANE GO:0032496| response to lipopolysaccharide MPO;ELANE;PTGS2 GO:0043066| negative regulation of apoptotic process MPO;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;PRTN3 GO:0055114| oxidation-reduction process MPO;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation ELANE;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;ELANE 39490:[DB00480 DB07692] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07692|1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine PKM common genes common pathways GO:0010033| response to organic substance PTGS2;PKM 39491:[DB00480 DB00179] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00179|Masoprocol ALOX5;SHBG;CYP2J2 common genes common pathways GO:0006954| inflammatory response ALOX5;PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0055114| oxidation-reduction process CYP2J2;ALOX5;PTGS2 39492:[DB00480 DB08950] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08950|Indoramin ADRA1A common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0042493| response to drug ABCB1;ADRA1A;PTGS2 GO:0007568| aging PTGS2;ADRA1A 39493:[DB00480 DB07879] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;HDAC4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;TNFSF11 GO:0006954| inflammatory response PTGS2;HDAC4 GO:0008285| negative regulation of cell proliferation PTGS2;HDAC4;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC4;TNFSF11 GO:0008284| positive regulation of cell proliferation HDAC4;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HDAC4 GO:0042493| response to drug PTGS2;ABCB1;HDAC4 39494:[DB00480 DB07453] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07453|2-PHENYL-4H-BENZO[H]CHROMEN-4-ONE CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 39495:[DB00480 DB02179] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02179|O-Trifluoromethylphenyl Anthranilic Acid TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0010469| regulation of receptor activity TTR;TNFSF11 39496:[DB00480 DB03747] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03747|3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol HEXB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HEXB 39497:[DB00480 DB06819] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06819|Phenylbutyric acid tyrB;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;PTGS2 39498:[DB00480 DB07668] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07668|3-(4-DIETHYLAMINO-2-HYDROXY-PHENYL)-2-METHYL-PROPIONIC ACID CTRB1 common genes common pathways 39499:[DB00480 DB07383] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07383|N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE CTRB1 common genes common pathways 39500:[DB00480 DB02611] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02611|Balanol Analog 1 PRKACA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA GO:0034605| cellular response to heat PTGS2;PRKACA 39501:[DB00480 DB05304] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05304|WX-G250 CA9;IL2 common genes common pathways GO:0006955| immune response TNFSF11;IL2 GO:0010469| regulation of receptor activity TNFSF11;IL2 GO:0042493| response to drug CA9;PTGS2;ABCB1 GO:0050728| negative regulation of inflammatory response IL2;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;IL2 GO:0007155| cell adhesion CDH5;IL2 39502:[DB00480 DB04885] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04885|Cilansetron HTR3A common genes common pathways 39503:[DB00480 DB00419] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00419|Miglustat UGCG common genes common pathways GO:0006629| lipid metabolic process PTGS2;UGCG 39504:[DB00480 DB01763] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01763|7-thionicotinamide-adenine-dinucleotide phosphate NNT common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NNT 39505:[DB00480 DB00155] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0043066| negative regulation of apoptotic process DDAH2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;TNFSF11 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0055114| oxidation-reduction process NOS3;NOS1;NOS2;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1;NOS3 GO:0042493| response to drug PTGS2;OTC;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process DDAH1;DDAH2;ASS1;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:1990830| TNFSF11;PADI2 GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0001525| angiogenesis PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;DDAH1;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 39506:[DB00480 DB07096] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07096|6-AMINO-BENZO[DE]ISOQUINOLINE-1,3-DIONE PARP1 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;TNFSF11 39507:[DB00480 DB07272] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07272|N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE MAPK8IP1;MAPK8 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;MAPK8 GO:0071260| cellular response to mechanical stimulus MAPK8;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;MAPK8;MAPK8IP1 39508:[DB00480 DB01091] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01091|Butenafine SQLE common genes common pathways GO:0055114| oxidation-reduction process PTGS2;SQLE GO:0010033| response to organic substance SQLE;PTGS2 39509:[DB00480 DB07003] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07003|(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine NOS2 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;NOS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0055114| oxidation-reduction process NOS2;PTGS2 39510:[DB00480 DB12340] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12340|Navitoclax BCL2;BCL2L2;BAD common genes common pathways GO:0051384| response to glucocorticoid stimulus BAD;BCL2;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BCL2 GO:0014070| response to organic cyclic compound BAD;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;BCL2;CDH5 GO:0001503| ossification TNFSF11;BCL2 GO:0071260| cellular response to mechanical stimulus PTGS2;BAD GO:0009314| response to radiation BCL2;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;BAD GO:0071456| cellular response to hypoxia BCL2;BAD;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;BAD GO:0098609| CDH5;BCL2 GO:0006979| response to oxidative stress PTGS2;BCL2 GO:0055085| transmembrane transport ABCB1;BCL2 GO:0010033| response to organic substance BAD;PTGS2 GO:0009887| organ morphogenesis TNFSF11;BCL2 GO:0034097| response to cytokine stimulus PTGS2;BCL2 GO:0008284| positive regulation of cell proliferation BCL2;PTGS2 GO:0043066| negative regulation of apoptotic process BCL2;PTGS2;BCL2L2 GO:0042493| response to drug PTGS2;ABCB1;BCL2;BAD GO:0019221| cytokine-mediated signaling pathway BAD;TNFSF11 39511:[DB00480 DB04606] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04606|2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE) F7 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F7;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0014070| response to organic cyclic compound F7;PTGS2 39512:[DB00480 DB04890] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04890|Bepotastine HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory PTGS2;HRH1 39513:[DB00480 DB03661] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03661|Cysteinesulfonic Acid CTSL;def;GLIPR2;def;fabH;PTPN1;CDC25B common genes common pathways GO:0007257| activation of JUN kinase activity PTPN1;TNFSF11 GO:0008284| positive regulation of cell proliferation CDC25B;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle CDC25B;ABCB1 39514:[DB00480 DB07992] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07992|3-SULFOOXY-1H-INDOLE ALB common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 39515:[DB00480 DB03101] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03101|Ribose-1-Phosphate PNP common genes common pathways GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006955| immune response PNP;TNFSF11 GO:0042493| response to drug PTGS2;ABCB1;PNP 39516:[DB00480 DB08055] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08055|N-(2-chlorophenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade LCK;TNFSF11 GO:0042493| response to drug ABCB1;LCK;PTGS2 GO:0042127| regulation of cell proliferation LCK;PTGS2 GO:0050870| positive regulation of T cell activation LCK;TNFSF11 39517:[DB00480 DB04884] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0042493| response to drug HTR1B;ABCB1;HTR2C;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP3A4 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 39518:[DB00480 DB13981] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13981|Nomegestrol acetate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39519:[DB00480 DB01776] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01776|M-Cresol INS common genes common pathways GO:0008284| positive regulation of cell proliferation INS;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;INS GO:0097756| INS;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;INS GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INS GO:0051092| positive regulation of NF-kappaB transcription factor activity INS;TNFSF11 GO:0090336| positive regulation of brown fat cell differentiation INS;PTGS2 39520:[DB00480 DB09017] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09017|Brotizolam CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39521:[DB00480 DB09087] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09087|Potassium alum ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS2 39522:[DB00480 DB07342] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07342|1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone HMOX1 common genes common pathways GO:0043065| positive regulation of apoptotic process HMOX1;PTGS2 GO:0001525| angiogenesis PTGS2;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;TNFSF11 GO:0008285| negative regulation of cell proliferation HMOX1;PTGS2;CDH5 GO:0008217| regulation of blood pressure PTGS2;HMOX1 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2 GO:0055114| oxidation-reduction process HMOX1;PTGS2 GO:0051260| protein homooligomerization HMOX1;TNFSF11 GO:0006979| response to oxidative stress HMOX1;PTGS2 GO:0034605| cellular response to heat HMOX1;PTGS2 GO:0071456| cellular response to hypoxia HMOX1;PTGS2 39523:[DB00480 DB04377] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04377|Meglutol HMGCR common genes common pathways GO:0006629| lipid metabolic process PTGS2;HMGCR GO:0097756| PTGS2;HMGCR GO:0007568| aging HMGCR;PTGS2 GO:0055114| oxidation-reduction process HMGCR;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR 39524:[DB00480 DB08206] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08206|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0010469| regulation of receptor activity TTR;TNFSF11 39525:[DB00480 DB03010] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle TUBB4A;TUBB;TUBB4B;TUBA4A;ABCB1;TUBA1A 39526:[DB00480 DB02147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02147|Cyclo-Tetrametavanadate C3 common genes common pathways GO:0006631| fatty acid metabolic process C3;PTGS2 GO:0006629| lipid metabolic process C3;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;C3 GO:0006955| immune response TNFSF11;C3 GO:0006954| inflammatory response PTGS2;C3 39527:[DB00480 DB04405] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04405|2-[2-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Ethyl]-4-(4'-Ethoxy-1,1'-Biphenyl-4-Yl)-4-Oxobutanoic Acid MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;TNFSF11 39528:[DB00480 DB04106] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04106|Fotemustine TXNRD1 common genes common pathways GO:0098869| PTGS2;TXNRD1 GO:0055114| oxidation-reduction process PTGS2;TXNRD1 39529:[DB00480 DB03042] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03042|5-Phosphoarabinonic Acid GPI common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPI;PTGS2 GO:0001525| angiogenesis GPI;PTGS2 GO:0010469| regulation of receptor activity GPI;TNFSF11 GO:0032355| response to estradiol stimulus GPI;PTGS2 39530:[DB00480 DB00032] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00032|Menotropins FSHR;LHCGR common genes common pathways GO:0045670| regulation of osteoclast differentiation LHCGR;FSHR;TNFSF11 39531:[DB00480 DB03104] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03104|RU82129 SRC common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:1902533| TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization CRBN;SRC 39532:[DB00480 DB01672] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01672|2,3-Dihydroxy-Benzoic Acid LCN2 common genes common pathways 39533:[DB00480 DB00924] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2D6;CYP3A4 GO:0007613| memory PTGS2;HTR2A GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1;CYP1A2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6;CYP1A2 GO:0042493| response to drug UGT1A1;PTGS2;HTR2A;ABCB1;CYP1A2 GO:0007568| aging PTGS2;HTR2A GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance UGT1A1;PTGS2;CYP1A2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A 39534:[DB00480 DB11652] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11652|Tucatinib ERBB2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade ERBB2;TNFSF11 GO:0043406| positive regulation of MAP kinase activity ERBB2;TNFSF11 39535:[DB00480 DB02141] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02141|S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0001525| angiogenesis PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 39536:[DB00480 DB01591] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01591|Solifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39537:[DB00480 DB08615] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08615|2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 39538:[DB00480 DB13158] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 39539:[DB00480 DB04112] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04112|1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G2A 39540:[DB00480 DB02097] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02097|Cytidine UCK2 common genes common pathways 39541:[DB00480 DB14042] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14042|Galcanezumab CALCA;CALCB common genes common pathways GO:0008217| regulation of blood pressure PTGS2;CALCA GO:0010469| regulation of receptor activity CALCA;TNFSF11;CALCB 39542:[DB00480 DB05416] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0071456| cellular response to hypoxia PTGS2;PPARD GO:0046697| decidualization PTGS2;PPARD GO:0010033| response to organic substance PTGS2;PPARD GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA GO:0043066| negative regulation of apoptotic process PTGS2;PPARD GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARD;PPARA GO:0030154| cell differentiation TNFSF11;PPARD GO:0007566| embryo implantation PTGS2;PPARD GO:0006629| lipid metabolic process PPARD;PPARA;PTGS2 39543:[DB00480 DB05993] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05993|PRX-07034 HTR6 common genes common pathways 39544:[DB00480 DB13914] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13914|Volixibat SLC10A2 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC10A2 GO:0006810| transport SLC10A2;ABCB1 39545:[DB00480 DB03317] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03317|Heme C cycA;cycM;CYP2C9;ccpA;cycA;CYCS common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PTGS2 GO:0055114| oxidation-reduction process CYCS;PTGS2;CYP2C9 39546:[DB00480 DB04027] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04027|D-Arginine CKM common genes common pathways 39547:[DB00480 DB06433] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways GO:0001525| angiogenesis PTGS2;TYMP GO:0007275| multicellular organismal development TNFSF11;TYMP GO:0030154| cell differentiation TNFSF11;TYMP GO:0055114| oxidation-reduction process PTGS2;RRM1 GO:0010469| regulation of receptor activity TNFSF11;TYMP 39548:[DB00480 DB04516] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04516|2-Deoxy-Glucitol-6-Phosphate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;ISYNA1 39549:[DB00480 DB03109] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03109|N-Acetyl-D-Allosamine CHIT1 common genes common pathways GO:0006955| immune response TNFSF11;CHIT1 39550:[DB00480 DB06727] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06727|Sparteine CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 39551:[DB00480 DB00406] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00406|Gentian violet cation SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;ABCB1 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0006855| drug transmembrane transport SLC22A1;ABCB1 39552:[DB00480 DB01818] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01818|O3-Sulfonylgalactose MBL2 common genes common pathways GO:0006979| response to oxidative stress MBL2;PTGS2 39553:[DB00480 DB05309] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05309|TP-508 FGF4 common genes common pathways GO:0030154| cell differentiation TNFSF11;FGF4 GO:0007275| multicellular organismal development FGF4;TNFSF11 GO:0010469| regulation of receptor activity FGF4;TNFSF11 GO:1990830| TNFSF11;FGF4 GO:0043066| negative regulation of apoptotic process PTGS2;FGF4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;FGF4 GO:0008284| positive regulation of cell proliferation PTGS2;FGF4 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGF4 39554:[DB00480 DB03621] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03621|L-709,587 FKBP1A common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A GO:0019221| cytokine-mediated signaling pathway FKBP1A;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A 39555:[DB00480 DB12212] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12212|Landiolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 39556:[DB00480 DB05050] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05050|ADL5859 OPRD1 common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006955| immune response TNFSF11;OPRD1 GO:0019233| sensory perception of pain OPRD1;PTGS2 39557:[DB00480 DB00929] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways GO:0070371| ERK1 and ERK2 cascade PTGER4;TNFSF11 GO:0006955| immune response PTGER4;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;PTGER4 GO:0031622| positive regulation of fever generation PTGS2;PTGER3 GO:0050728| negative regulation of inflammatory response CDH5;PTGER4 GO:0032496| response to lipopolysaccharide PTGER2;PTGER4;PTGS2 GO:0042127| regulation of cell proliferation PTGER2;PTGS2 39558:[DB00480 DB01270] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01270|Ranibizumab VEGFA common genes common pathways GO:0030154| cell differentiation VEGFA;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2 GO:0001525| angiogenesis VEGFA;PTGS2 GO:0007275| multicellular organismal development TNFSF11;VEGFA GO:0042327| positive regulation of phosphorylation TNFSF11;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0010469| regulation of receptor activity VEGFA;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;VEGFA GO:0060749| mammary gland alveolus development TNFSF11;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VEGFA GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;VEGFA 39559:[DB00480 DB00799] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00799|Tazarotene RARA;RXRB;RARG;RARB;CYP2C8 common genes common pathways GO:1990830| RARG;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;RARA GO:0055114| oxidation-reduction process PTGS2;CYP2C8 GO:0034097| response to cytokine stimulus PTGS2;RARA GO:0043066| negative regulation of apoptotic process RARB;RARA;PTGS2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;TNFSF11;RARB;RARG;RARA GO:0008284| positive regulation of cell proliferation RARB;RARG;PTGS2;RARA GO:0008285| negative regulation of cell proliferation RARG;RARA;PTGS2;CDH5;RARB GO:0043065| positive regulation of apoptotic process RARB;PTGS2;RARG 39560:[DB00480 DB01581] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01581|Sulfamerazine ALB common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2 39561:[DB00480 DB07246] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process MMP9;PTGS2 GO:0007566| embryo implantation MMP9;PTGS2 GO:0043065| positive regulation of apoptotic process MMP9;PTGS2 GO:0001503| ossification TNFSF11;MMP9 39562:[DB00480 DB13385] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13385|Dihydroergocryptine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39563:[DB00480 DB08810] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0007568| aging PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0008284| positive regulation of cell proliferation HTR2A;HTR1A;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A 39564:[DB00480 DB01000] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0055085| transmembrane transport SLC15A2;SLC22A5;ABCB1;SLC15A1 GO:0006855| drug transmembrane transport SLC22A5;ABCB1 39565:[DB00480 DB00847] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00847|Cysteamine SST;NPY2R;MPO common genes common pathways GO:0006979| response to oxidative stress MPO;PTGS2 GO:0007568| aging MPO;NPY2R;PTGS2 GO:0010469| regulation of receptor activity SST;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;MPO GO:0032496| response to lipopolysaccharide PTGS2;MPO GO:0010243| response to organic nitrogen PTGS2;SST GO:0055114| oxidation-reduction process MPO;PTGS2 GO:0042493| response to drug PTGS2;SST;ABCB1 GO:0008285| negative regulation of cell proliferation PTGS2;SST;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2;NPY2R 39566:[DB00480 DB07029] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07029|4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 39567:[DB00480 DB06939] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06939|N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion DPP4;CDH5 39568:[DB00480 DB06162] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06162|Lumiliximab FCER2 common genes common pathways 39569:[DB00480 DB04270] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04270|(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid PPARG common genes common pathways GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0010033| response to organic substance PTGS2;PPARG 39570:[DB00480 DB08186] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08186|(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE KAT2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter KAT2B;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;KAT2B;PTGS2 39571:[DB00480 DB06268] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways GO:0019722| calcium-mediated signaling EDNRB;TNFSF11 GO:0014070| response to organic cyclic compound EDNRB;PTGS2 GO:0008217| regulation of blood pressure EDNRB;EDNRA;PTGS2 GO:0019233| sensory perception of pain EDNRB;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP3A4 GO:0007568| aging PTGS2;EDNRB GO:0032496| response to lipopolysaccharide PTGS2;EDNRB GO:0043066| negative regulation of apoptotic process PTGS2;EDNRB GO:0008284| positive regulation of cell proliferation PTGS2;EDNRB GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS2;CYP2C19 39572:[DB00480 DB06097] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06097|GSK-923295 CENPE common genes common pathways GO:0007275| multicellular organismal development TNFSF11;CENPE 39573:[DB00480 DB09234] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09234|Darodipine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39574:[DB00480 DB09459] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09459|L-tartaric acid B3GAT1;HIF1AN common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HIF1AN 39575:[DB00480 DB08200] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08200|(1R)-menthyl hexyl phosphonate group BCHE common genes common pathways GO:0042493| response to drug PTGS2;BCHE;ABCB1 GO:0007612| learning PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE 39576:[DB00480 DB05787] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05787|LM-609 ITGB3 common genes common pathways GO:0007155| cell adhesion ITGB3;CDH5 39577:[DB00480 DB08884] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0042493| response to drug ABCC4;ABCC2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process ABCC4;PTGS2 GO:0010243| response to organic nitrogen ABCC4;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;PTGS2 GO:0032496| response to lipopolysaccharide ABCC2;PTGS2 GO:0055085| transmembrane transport SLCO1B1;ABCC3;SLCO1B3;ABCC4;ABCB1;ABCC2 GO:0010033| response to organic substance ABCC4;PTGS2 GO:0006810| transport ABCC3;ABCC2;ABCB1 GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0014070| response to organic cyclic compound ABCC4;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC3 GO:0042908| xenobiotic transport ABCB1;ABCC3 39578:[DB00480 DB12712] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12712|Pilsicainide ABCB11 common genes common pathways GO:0006810| transport ABCB1;ABCB11 GO:0055085| transmembrane transport ABCB1;ABCB11 39579:[DB00480 DB12961] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12961|Leukotriene B4 LTB4R;LTB4R2;PPARA common genes common pathways GO:0006954| inflammatory response LTB4R;PTGS2 GO:0006955| immune response TNFSF11;LTB4R GO:0006629| lipid metabolic process PPARA;PTGS2 GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0050728| negative regulation of inflammatory response PPARA;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;TNFSF11 39580:[DB00480 DB05458] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05458|Pozanicline CHRNA4;CHRNB2 common genes common pathways GO:0007612| learning CHRNB2;PTGS2 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0019233| sensory perception of pain PTGS2;CHRNA4;CHRNB2 GO:0007613| memory PTGS2;CHRNB2 39581:[DB00480 DB05190] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05190|XL281 BRAF;RAF1 common genes common pathways GO:0007275| multicellular organismal development RAF1;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;RAF1 GO:0033138| positive regulation of peptidyl-serine phosphorylation BRAF;PTGS2;RAF1 GO:0030154| cell differentiation RAF1;BRAF;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;RAF1;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RAF1 GO:0043066| negative regulation of apoptotic process BRAF;PTGS2;RAF1 GO:0042127| regulation of cell proliferation BRAF;PTGS2 GO:0009887| organ morphogenesis BRAF;TNFSF11 39582:[DB00480 DB08609] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08609|(2R)-N-{4-[Ethyl(phenyl)sulfamoyl]-2-methylphenyl}-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide PDK2 common genes common pathways 39583:[DB00480 DB01437] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP11A1;CYP2D6 GO:0006810| transport GABRB1;GABRA6;GABRA4;GABRD;GABRA3;GABRA5;GABRB2;GABRG2;ABCB1;GABRA1;GABRB3 GO:0042493| response to drug ABCB1;GABRG3;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;CYP11A1;PTGS2 39584:[DB00480 DB06778] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06778|Cupric sulfate PAH;SOD1;MAOA;MAOB;LOX;MT-CO1;TYR;ALB;CP common genes common pathways GO:0043065| positive regulation of apoptotic process SOD1;PTGS2 GO:0033280| response to vitamin D PTGS2;TYR GO:0008217| regulation of blood pressure PTGS2;SOD1 GO:0007566| embryo implantation SOD1;PTGS2 GO:0055114| oxidation-reduction process MT-CO1;LOX;CP;PAH;PTGS2;MAOA;TYR;MAOB;SOD1 GO:0042493| response to drug MAOB;SOD1;PTGS2;ABCB1;LOX GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0043066| negative regulation of apoptotic process ALB;PTGS2;SOD1 GO:0010033| response to organic substance PTGS2;SOD1 GO:0007568| aging SOD1;PTGS2;MT-CO1 GO:0006979| response to oxidative stress SOD1;PTGS2;MT-CO1 GO:0098869| ALB;PTGS2 39585:[DB00480 DB01038] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01038|Carphenazine DRD2;DRD1;DRD5 common genes common pathways GO:0007613| memory DRD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0007612| learning DRD1;PTGS2;DRD5 GO:0042493| response to drug PTGS2;DRD1;DRD2;ABCB1 39586:[DB00480 DB06204] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0006810| transport ABCB1;SLC6A2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP2C19;PTGS2 GO:0042493| response to drug SLC6A2;PTGS2;ABCB1;SLC6A4 GO:0007613| memory PTGS2;SLC6A4 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0019233| sensory perception of pain OPRM1;OPRK1;PTGS2;OPRD1 GO:0006629| lipid metabolic process PTGS2;UGT2B7;CYP2C9;CYP2D6 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0006955| immune response TNFSF11;OPRK1;OPRD1 39587:[DB00480 DB09028] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0006810| transport CHRNA6;ABCB1 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0007612| learning PTGS2;CHRNB2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0007613| memory CHRNB2;PTGS2;CHRNA7 GO:0019233| sensory perception of pain CHRNB2;CHRNA4;PTGS2 39588:[DB00480 DB08234] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08234|5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 39589:[DB00480 DB00744] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0098869| PTGS1;ALB;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process CYP2C9;CYP1A2;CYP3A4;ALOX5;PTGS1;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0006954| inflammatory response PTGS2;ALOX5;PTGS1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1;CYP3A4;CYP1A2;CYP2C9 39590:[DB00480 DB05777] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05777|Thrombomodulin Alfa F2;F5 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;F2 GO:0010469| regulation of receptor activity F2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;F2 39591:[DB00480 DB04638] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04638|2,5-DI-(TERT-BUTYL)-1,4,BENZOHYDROQUINONE ATP2A1 common genes common pathways 39592:[DB00480 DB03351] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03351|Sri-9439 DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 39593:[DB00480 DB00937] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug ABCB1;SLC6A3;PTGS2;SLC6A2 GO:0007568| aging SLC6A3;PTGS2 GO:0006810| transport ABCB1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;SLC6A3;ABCB1 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 39594:[DB00480 DB01199] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01199|Tubocurarine CHRNA2;HTR3A;ACHE;CHRNA7;BCHE;SLC22A1;SLC22A2 common genes common pathways GO:0007613| memory PTGS2;CHRNA7 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0006855| drug transmembrane transport SLC22A2;SLC22A1;ABCB1 GO:0007155| cell adhesion ACHE;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug PTGS2;BCHE;ABCB1 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0055085| transmembrane transport SLC22A2;SLC22A1;ABCB1 39595:[DB00480 DB09067] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09067|Corticorelin ovine triflutate CRHR1 common genes common pathways GO:0006955| immune response CRHR1;TNFSF11 39596:[DB00480 DB08605] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08605|6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL DECR1;fabI common genes common pathways GO:0006629| lipid metabolic process PTGS2;DECR1 GO:0006631| fatty acid metabolic process DECR1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;DECR1 39597:[DB00480 DB05934] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05934|CTCE-0214 CXCL12 common genes common pathways GO:0008284| positive regulation of cell proliferation CXCL12;PTGS2 GO:0007155| cell adhesion CXCL12;CDH5 GO:0010469| regulation of receptor activity TNFSF11;CXCL12 GO:0009314| response to radiation PTGS2;CXCL12 GO:0006955| immune response CXCL12;TNFSF11 39598:[DB00480 DB06408] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06408|Taribavirin PB1;NT5C2;IMPDH1;ENPP1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;IMPDH1 GO:0006955| immune response ENPP1;TNFSF11 39599:[DB00480 DB00247] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A;HTR2B GO:0007568| aging HTR2A;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug HTR2B;PTGS2;HTR2A;ABCB1;HTR1B;HTR2C GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A;HTR2B;HTR2A GO:0007613| memory HTR2A;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0006629| lipid metabolic process CYP3A4;PTGS2 39600:[DB00480 DB03515] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03515|Equilenin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39601:[DB00480 DB03126] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03126|Mant-Adp MYH14 common genes common pathways 39602:[DB00480 DB04977] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2E1;CYP4A11;CYP2A6;CYP3A4 GO:0006631| fatty acid metabolic process PTGS2;CYP4A11 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39603:[DB00480 DB05931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05931|Pegdinetanib KDR common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0008284| positive regulation of cell proliferation KDR;PTGS2 GO:0030154| cell differentiation KDR;TNFSF11 GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0001525| angiogenesis KDR;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR 39604:[DB00480 DB01520] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01520|Tenocyclidine GRIN3A;GRIN3B;GRIN2A;GRIN2C;GRIN2B;GRIN2D;CHRNA7 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;GRIN2A GO:0019233| sensory perception of pain PTGS2;GRIN2A GO:0019722| calcium-mediated signaling GRIN2C;GRIN2D;TNFSF11;GRIN2A;GRIN2B GO:0007613| memory GRIN2A;CHRNA7;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;GRIN2A GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 GO:0007612| learning PTGS2;GRIN2A GO:0006810| transport GRIN2B;GRIN2A;ABCB1;GRIN2C 39605:[DB00480 DB00724] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006955| immune response TLR7;TNFSF11 GO:0006954| inflammatory response TLR8;TLR7;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071260| cellular response to mechanical stimulus TLR8;TLR7;PTGS2 39606:[DB00480 DB03467] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03467|Naringenin ESR1;AKR1C1;CYP1B1;KANSL3;SHBG;CYP19A1;ESR2;SLCO2B1;ABCB1;ABCC1;ABCG2 common genes ABCB1 common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;TNFSF11 GO:0007155| cell adhesion CDH5;CYP1B1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:1901529| ABCB1 GO:0042493| response to drug ABCB1;ABCC1;ABCG2;PTGS2 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process PTGS2;AKR1C1;CYP19A1;CYP1B1 GO:2001225| regulation of chloride transport ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0051260| protein homooligomerization AKR1C1;TNFSF11 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO2B1;ABCC1;ABCG2 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0043065| positive regulation of apoptotic process PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1;TNFSF11 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;CYP1B1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 39607:[DB00480 DB02230] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02230|Immucillin-G PNP common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006955| immune response TNFSF11;PNP 39608:[DB00480 DB00367] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;SRD5A1;CYP3A4 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0030154| cell differentiation SRD5A1;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0014070| response to organic cyclic compound SRD5A1;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;AR;PGR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0055114| oxidation-reduction process SRD5A1;PTGS2;CYP19A1;CYP3A4 GO:0042493| response to drug SRD5A1;PTGS2;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0006810| transport AR;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;SRD5A1;ESR1 39609:[DB00480 DB02911] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02911|2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine NOS3 common genes common pathways GO:0001525| angiogenesis PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0055114| oxidation-reduction process PTGS2;NOS3 GO:0051926| negative regulation of calcium ion transport PTGS2;NOS3 39610:[DB00480 DB07579] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07579|BIS-1,2-{[(Z)-2-CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBAMOYL}-ETHANE APCS common genes common pathways 39611:[DB00480 DB07756] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07756|1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 39612:[DB00480 DB08612] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08612|1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE CES1P1 common genes common pathways 39613:[DB00480 DB08347] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08347|4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile ADRB1 common genes common pathways GO:0050873| brown fat cell differentiation ADRB1;PTGS2 39614:[DB00480 DB07142] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07142|5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 39615:[DB00480 DB08360] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08360|2-(4-ETHYLPIPERAZIN-1-YL)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 39616:[DB00480 DB02888] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02888|FKB-001 FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0007179| transforming growth factor beta receptor signaling pathway FKBP1A;CDH5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A 39617:[DB00480 DB03766] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03766|Propanoic acid cpo;GPHN;FABP4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GPHN GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0050727| regulation of inflammatory response FABP4;PTGS2 39618:[DB00480 DB01193] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0006810| transport ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:1901529| ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0050873| brown fat cell differentiation ADRB1;PTGS2;ADRB2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 39619:[DB00480 DB01624] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0006954| inflammatory response PTGS2;HRH1 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;DRD2;PTGS2 GO:0007613| memory HRH1;DRD1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;HTR2A;ADRA1A;PTGS2 GO:0042493| response to drug DRD1;HTR2A;ADRA1A;DRD2;PTGS2;ABCB1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0007612| learning PTGS2;DRD1;DRD5 GO:0008284| positive regulation of cell proliferation ADRA2A;HTR2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007568| aging PTGS2;ADRA1A;HTR2A 39620:[DB00480 DB03552] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03552|3-Tyrosine TH common genes common pathways GO:0032496| response to lipopolysaccharide TH;PTGS2 GO:0007612| learning PTGS2;TH GO:0055114| oxidation-reduction process TH;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;TH GO:0042493| response to drug TH;PTGS2;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;TH GO:0009887| organ morphogenesis TNFSF11;TH GO:0007613| memory PTGS2;TH GO:0014070| response to organic cyclic compound TH;PTGS2 39621:[DB00480 DB02464] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02464|Benzylamine PRSS2;PRSS1 common genes common pathways 39622:[DB00480 DB08208] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08208|2-[(4-ETHYNYL-2-FLUOROPHENYL)AMINO]-3,4-DIFLUORO-N-(2-HYDROXYETHOXY)BENZAMIDE MAP2K1 common genes common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAP2K1 GO:0008285| negative regulation of cell proliferation CDH5;MAP2K1;PTGS2 39623:[DB00480 DB02468] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02468|12-Phenylheme HMOX1 common genes common pathways GO:0051260| protein homooligomerization HMOX1;TNFSF11 GO:0006979| response to oxidative stress HMOX1;PTGS2 GO:0071456| cellular response to hypoxia HMOX1;PTGS2 GO:0034605| cellular response to heat HMOX1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;HMOX1 GO:0008217| regulation of blood pressure PTGS2;HMOX1 GO:0008285| negative regulation of cell proliferation CDH5;HMOX1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HMOX1;TNFSF11 GO:0001525| angiogenesis HMOX1;PTGS2 39624:[DB00480 DB08000] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08000|2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0010033| response to organic substance AKR1B1;PTGS2 39625:[DB00480 DB00171] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00171|ATP ABL2;ABCB1;ABCG1;ABCC2;ABCA1;ACSS2;ALK;NAE1;PRKAA1;ARAF;ACVRL1;ACSL1;NT5C2;ASNA1;ABCC9;AKT1;ADRBK1;APAF1;ACSS1;ACVR1B;ACVR1;ABCB11;ASNS;CDK15;SLC25A4;ABCC8;ASS1;AFG3L2;ADRBK2;AMHR2;TNK2;ABL1;ADCY1;ABCC6;ABCC4;ABCC1;CFTR;PIK3CA;CSNK2A1;CSNK2B;P2RY11;PPP5C;ADK common genes ABCB1 common pathways GO:0043066| negative regulation of apoptotic process AKT1;PTGS2;ASNS;ARAF;PRKAA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ACVRL1;TNFSF11;AKT1;ACVR1B;ACVR1 GO:0008284| positive regulation of cell proliferation PTGS2;AKT1;PRKAA1;CSNK2A1 GO:0007155| cell adhesion ABL2;CDH5;ABL1 GO:0071318| cellular response to ATP P2RY11;PTGS2 GO:0032496| response to lipopolysaccharide ABCC2;PTGS2;ABCC8 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation PTGS2;ALK;TNK2;ABL2;ABL1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKT1;ABCC4 GO:0010243| response to organic nitrogen ABCC4;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PIK3CA GO:0006631| fatty acid metabolic process PTGS2;PRKAA1;ACSL1 GO:0042493| response to drug ABCC1;ABCC9;PTGS2;ABCC8;ABCC6;ADCY1;ABCB1;ABCC2;ABCA1;ACSL1;ABCC4 GO:0016567| protein ubiquitination AKT1;CRBN GO:0099040| ABCB1 GO:0055114| oxidation-reduction process ABCC4;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0006979| response to oxidative stress AKT1;PTGS2;ABCC2;ABL1 GO:0045429| positive regulation of nitric oxide biosynthetic process ASS1;AKT1;PTGS2 GO:0051260| protein homooligomerization TNFSF11;APAF1 GO:0006810| transport ASNA1;ABCB1;ABCC2;ABCB11;ABCC6;SLC25A4;ABCC1 GO:0007568| aging PTGS2;AKT1;APAF1 GO:0071456| cellular response to hypoxia PTGS2;AKT1;PRKAA1 GO:0010033| response to organic substance ACSL1;ABCG1;ABCC4;AKT1;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway AMHR2;ACVR1;CDH5;ACVRL1 GO:0055085| transmembrane transport CFTR;SLC25A4;ABCC6;ABCB11;ABCC9;ABCC1;ABCC8;ABCG1;ABCC4;ABCC2;ABCB1;ABCA1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0043065| positive regulation of apoptotic process APAF1;ABL1;PTGS2;AKT1 GO:0071260| cellular response to mechanical stimulus AKT1;PTGS2 GO:0006629| lipid metabolic process ACSL1;PRKAA1;ABCA1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;APAF1;AKT1;ARAF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade PPP5C;TNFSF11;ABL1 GO:0001525| angiogenesis PTGS2;PIK3CA;ACVRL1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;AKT1 GO:0006954| inflammatory response PIK3CA;AKT1;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity ALK;TNFSF11 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;AKT1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;AKT1 GO:0006633| fatty acid biosynthetic process PRKAA1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PIK3CA;AKT1;PTGS2;ARAF GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1;ABCA1 GO:0010226| response to lithium ion ADCY1;PTGS2 GO:0019722| calcium-mediated signaling P2RY11;TNFSF11 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0007613| memory ABCC8;PTGS2 GO:0030154| cell differentiation ARAF;AKT1;TNFSF11;APAF1;TNK2 GO:0001955| blood vessel maturation CDH5;ACVRL1 GO:0008217| regulation of blood pressure PTGS2;ACVRL1 GO:0008285| negative regulation of cell proliferation PTGS2;ACVRL1;CSNK2B;CDH5 GO:0014070| response to organic cyclic compound PTGS2;ACSL1;ABCC4 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1 39626:[DB00480 DB05766] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0042493| response to drug PTGS2;DRD2;ABCB1;DRD3 GO:0007612| learning DRD3;PTGS2 GO:0008284| positive regulation of cell proliferation DRD3;CHRM1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11 39627:[DB00480 DB00123] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00123|L-Lysine SLC7A1;SLC7A4;SLC7A3;SLC7A2;KARS;SLC16A10;SLC22A4 common genes common pathways GO:0033209| tumor necrosis factor-mediated signaling pathway KARS;TNFSF11 GO:0006810| transport SLC7A2;SLC7A1;ABCB1;SLC7A4 GO:0055085| transmembrane transport SLC22A4;SLC16A10;ABCB1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;KARS GO:0050727| regulation of inflammatory response SLC7A2;PTGS2 GO:0070371| ERK1 and ERK2 cascade KARS;TNFSF11 39628:[DB00480 DB08883] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP2B6;CYP1A2;CYP3A4;CYP3A5;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2 39629:[DB00480 DB01812] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01812|Adenosine-3'-5'-Diphosphate HS3ST1;SULT2B1;RNASE2;SULT1A1;HS3ST3A1;RNASE1;SULT2A1;SULT1E1;NDST1;acpS;SULT1B1;topA common genes common pathways GO:0009887| organ morphogenesis TNFSF11;NDST1 GO:0006954| inflammatory response PTGS2;NDST1 GO:0006629| lipid metabolic process SULT1B1;SULT2A1;SULT2B1;SULT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;SULT2B1;CDH5 39630:[DB00480 DB03754] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03754|Tromethamine CANT1;NEIL1;AMD1;bioB;VEGFA;pgl;DCN common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA GO:0030154| cell differentiation VEGFA;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;VEGFA GO:0001525| angiogenesis PTGS2;VEGFA GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CANT1;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;VEGFA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process VEGFA;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0006979| response to oxidative stress PTGS2;NEIL1 GO:0010469| regulation of receptor activity VEGFA;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0007568| aging DCN;PTGS2 GO:0009887| organ morphogenesis TNFSF11;DCN GO:0043406| positive regulation of MAP kinase activity VEGFA;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VEGFA;DCN GO:0008284| positive regulation of cell proliferation PTGS2;VEGFA GO:0043066| negative regulation of apoptotic process PTGS2;VEGFA GO:0060749| mammary gland alveolus development VEGFA;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;DCN GO:0019221| cytokine-mediated signaling pathway TNFSF11;DCN 39631:[DB00480 DB07705] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07705|1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE CYP51A1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP51A1 GO:0006629| lipid metabolic process PTGS2;CYP51A1 39632:[DB00480 DB08519] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08519|N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine KDR common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process KDR;PTGS2 GO:0030154| cell differentiation TNFSF11;KDR GO:0001525| angiogenesis PTGS2;KDR GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR 39633:[DB00480 DB04335] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04335|Inosine PNP;deoD;XDH;SLC28A3 common genes common pathways GO:0006955| immune response TNFSF11;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0055114| oxidation-reduction process XDH;PTGS2 GO:0042493| response to drug ABCB1;PNP;PTGS2 39634:[DB00480 DB03909] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03909|Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate murC;INSR;ATP2A1;PDXK;PGK1;rbsK;KIF1A common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 GO:0007612| learning PTGS2;INSR GO:0008284| positive regulation of cell proliferation PTGS2;INSR GO:0009887| organ morphogenesis TNFSF11;INSR GO:0071456| cellular response to hypoxia PGK1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;PTGS2 GO:0007613| memory PTGS2;INSR 39635:[DB00480 DB02152] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02152|K-252a MET;MAP2K1 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;CDH5;PTGS2 GO:0070371| ERK1 and ERK2 cascade MAP2K1;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET 39636:[DB00480 DB03277] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03277|alpha-maltotriose AMY2B common genes common pathways 39637:[DB00480 DB06738] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0019722| calcium-mediated signaling GRIN1;GRIN2C;GRIN2D;TNFSF11;GRIN2A;GRIN2B GO:0007613| memory GRIN2A;GRIN1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0019233| sensory perception of pain OPRM1;GRIN2A;OPRK1;GRIN1;PTGS2;OPRD1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2;GRIN1 GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0006955| immune response TNFSF11;OPRK1;OPRD1 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0006810| transport ABCB1;GRIN2A;GRIN2B;GRIN2C GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0098869| PTGS2;PTGS1 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0007612| learning PTGS2;GRIN1;GRIN2A GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug GRIN2A;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;CYP2C9;CYP2C19;CYP2C8;PTGS2;PTGS1 39638:[DB00480 DB04875] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04875|Pralnacasan CASP1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;CASP1 GO:0071260| cellular response to mechanical stimulus CASP1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CASP1;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;CASP1 39639:[DB00480 DB08205] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08205|4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport ABCB1;TTR 39640:[DB00480 DB05223] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0010033| response to organic substance HDAC6;PTGS2 GO:0034605| cellular response to heat PTGS2;HDAC2 GO:0010469| regulation of receptor activity TNFSF11;HDAC6 GO:0042493| response to drug ABCB1;PTGS2;HDAC2;HDAC1 GO:0043066| negative regulation of apoptotic process HDAC2;PTGS2;HDAC1;HDAC3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;HDAC2;TNFSF11;HDAC3 GO:0008284| positive regulation of cell proliferation HDAC1;PTGS2;HDAC2 GO:0032496| response to lipopolysaccharide PTGS2;HDAC2;HDAC1 GO:0008285| negative regulation of cell proliferation CDH5;HDAC1;PTGS2 GO:0071498| cellular response to fluid shear stress HDAC3;PTGS2 39641:[DB00480 DB03788] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03788|GC-24 THRB common genes common pathways GO:0009887| organ morphogenesis THRB;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;THRB 39642:[DB00480 DB11148] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11148|Butamben CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;BCHE;ORM1;ALB common genes common pathways GO:0042493| response to drug ABCB1;BCHE;KCNJ11;PTGS2 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0032496| response to lipopolysaccharide KCNJ8;PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0055085| transmembrane transport CACNA1C;CACNA1D;CACNA1H;CACNA1B;KCNJ11;CACNA1S;CACNA1I;CACNA1A;CACNA1G;CACNA1F;ABCB1 GO:0098869| ALB;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;KCNJ11 GO:0006810| transport ABCB1;CACNA1I;CACNB4;CACNA1B;CACNB1;CACNB3;CACNG1 GO:0006954| inflammatory response ORM1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;CACNA1B GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE 39643:[DB00480 DB02678] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02678|2-Deoxy-2-Aminogalactose LGALS7 common genes common pathways 39644:[DB00480 DB12698] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0033280| response to vitamin D PTGS2;CD4 GO:0019722| calcium-mediated signaling TNFSF11;CCR5;CXCR4 GO:0050870| positive regulation of T cell activation TNFSF11;CD4 GO:0006955| immune response CD4;TNFSF11;CCR5 GO:0006954| inflammatory response CCR5;CXCR4;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CD4 GO:0032355| response to estradiol stimulus CD4;PTGS2 GO:0007155| cell adhesion CD4;CDH5 39645:[DB00480 DB01597] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process DPEP1;PTGS2 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0055085| transmembrane transport ABCB1;SLC22A6;SLC22A8 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process DPEP1;PTGS2 39646:[DB00480 DB04048] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04048|N-Carbamoyl-Alanine PRDX2 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PRDX2 GO:0055114| oxidation-reduction process PRDX2;PTGS2 GO:0006979| response to oxidative stress PTGS2;PRDX2 39647:[DB00480 DB00464] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00464|Sodium Tetradecyl Sulfate PROC;PROS1 common genes common pathways GO:1903142| CDH5;PROC GO:0043066| negative regulation of apoptotic process PTGS2;PROC GO:0050728| negative regulation of inflammatory response PROC;CDH5 39648:[DB00480 DB01709] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01709|2-phospho-D-glyceric acid kdsA;ENO3 common genes common pathways GO:0042493| response to drug ABCB1;ENO3;PTGS2 GO:0007568| aging PTGS2;ENO3 39649:[DB00480 DB09526] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09526|Hydroquinone TYR;ALB common genes common pathways GO:0033280| response to vitamin D TYR;PTGS2 GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process TYR;PTGS2 39650:[DB00480 DB07456] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07456|3-(1H-indol-3-yl)-4-(1-{2-[(2S)-1-methylpyrrolidinyl]ethyl}-1H-indol-3-yl)-1H-pyrrole-2,5-dione PDPK1 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;PDPK1 39651:[DB00480 DB08467] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08467|6-(2,3,4,5,6,7-HEXAHYDRO-2,4,4-TRIMETHYL-1-METYLENEINDEN-2-YL)-3-METHYLHEXA-2,4-DIENOIC ACID CRABP2 common genes common pathways 39652:[DB00480 DB04389] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04389|Ado-P-Ch2-P-Ps-Ado FHIT common genes common pathways 39653:[DB00480 DB02187] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0006629| lipid metabolic process PTGS2;HSD17B1;CYP3A4 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;HSD17B1;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 39654:[DB00480 DB08654] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08654|TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 39655:[DB00480 DB00043] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways GO:0006955| immune response MS4A2;TNFSF11 GO:0006954| inflammatory response PTGS2;MS4A2 39656:[DB00480 DB01194] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways GO:0006979| response to oxidative stress CA3;PTGS2 GO:0045780| positive regulation of bone resorption TNFSF11;CA2 GO:0010033| response to organic substance PTGS2;CA2 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 39657:[DB00480 DB09343] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0001525| angiogenesis PTGS2;TYMP GO:0007275| multicellular organismal development TYMP;TNFSF11 GO:0006855| drug transmembrane transport SLC22A2;SLC47A1;ABCB1 GO:0030154| cell differentiation TYMP;TNFSF11 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC47A1 GO:0010469| regulation of receptor activity TNFSF11;TYMP 39658:[DB00480 DB08608] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08608|4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE PDK2 common genes common pathways 39659:[DB00480 DB00974] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00974|Edetic Acid ADA;PON3;CYP19A1 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0050870| positive regulation of T cell activation TNFSF11;ADA GO:0007568| aging PTGS2;ADA GO:0042493| response to drug ADA;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP19A1 GO:0050728| negative regulation of inflammatory response ADA;CDH5 GO:0019372| lipoxygenase pathway PTGS2;PON3 GO:0043066| negative regulation of apoptotic process ADA;PTGS2 GO:0007155| cell adhesion ADA;CDH5 39660:[DB00480 DB00240] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 39661:[DB00480 DB05282] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05282|MCC AIFM1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;AIFM1 GO:0010942| positive regulation of cell death AIFM1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;AIFM1 39662:[DB00480 DB00954] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00954|Dirithromycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39663:[DB00480 DB05249] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05249|FavId CSF3R common genes common pathways GO:0007155| cell adhesion CDH5;CSF3R GO:0019221| cytokine-mediated signaling pathway CSF3R;TNFSF11 39664:[DB00480 DB08448] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08448|(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 39665:[DB00480 DB03690] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03690|(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide PITPNA common genes common pathways GO:0006629| lipid metabolic process PITPNA;PTGS2 39666:[DB00480 DB02850] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02850|(1-Tert-Butyl-5-Hydroxy-1h-Pyrazol-4-Yl)-(6-Methanesulfonyl-4'-Methoxy-2-Methyl-Biphenyl-3-Yl)-Methanone HPD common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HPD 39667:[DB00480 DB03608] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03608|Diminazene PRDX5;PRSS1;AOC1 common genes common pathways GO:0006954| inflammatory response PRDX5;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;PRDX5 GO:0055114| oxidation-reduction process AOC1;PRDX5;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;AOC1 GO:0043066| negative regulation of apoptotic process PRDX5;PTGS2 GO:0098869| PTGS2;PRDX5 GO:0006979| response to oxidative stress PTGS2;PRDX5 39668:[DB00480 DB06600] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06600|Nemonoxacin CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 39669:[DB00480 DB06497] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06497|Aplaviroc CCR5 common genes common pathways GO:0006955| immune response CCR5;TNFSF11 GO:0006954| inflammatory response PTGS2;CCR5 GO:0019722| calcium-mediated signaling TNFSF11;CCR5 39670:[DB00480 DB08707] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08707|4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine PIM1 common genes common pathways GO:0007275| multicellular organismal development PIM1;TNFSF11 GO:0043066| negative regulation of apoptotic process PIM1;PTGS2 39671:[DB00480 DB07717] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07717|(5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE AR common genes common pathways GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11 39672:[DB00480 DB06176] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes ABCB1 common pathways GO:0008285| negative regulation of cell proliferation CDH5;HDAC4;HDAC1;PTGS2 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006954| inflammatory response HDAC4;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity HDAC4;TNFSF11 GO:0071260| cellular response to mechanical stimulus HDAC4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0010033| response to organic substance HDAC6;CYP1A1;PTGS2 GO:0055085| transmembrane transport ABCC1;ABCB1;SLCO1B3 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0007568| aging PTGS2;CYP1A1 GO:0010469| regulation of receptor activity TNFSF11;HDAC6 GO:0034605| cellular response to heat HDAC2;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation HDAC4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;PTGS2;CYP2C19;CYP1A1;CYP3A5 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;HDAC4;ABCC1;HDAC2;PTGS2;HDAC1;CYP1A1 GO:0008284| positive regulation of cell proliferation HDAC2;PTGS2;HDAC1;HDAC4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;HDAC2;TNFSF11;HDAC4 GO:0043066| negative regulation of apoptotic process PTGS2;HDAC2;HDAC1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide HDAC1;CYP1A1;PTGS2;HDAC2 39673:[DB00480 DB00846] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39674:[DB00480 DB04585] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04585|DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID ARG1 common genes common pathways GO:0007568| aging PTGS2;ARG1 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0042493| response to drug PTGS2;ARG1;ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;ARG1 39675:[DB00480 DB01125] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01125|Anisindione GGCX common genes common pathways 39676:[DB00480 DB02205] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02205|6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One GAPDHS common genes common pathways GO:0055114| oxidation-reduction process GAPDHS;PTGS2 39677:[DB00480 DB04175] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04175|Mdl-29951 FBP1 common genes common pathways 39678:[DB00480 DB00748] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00748|Carbinoxamine HRH1;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C8;CYP2C19;CYP2E1 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 39679:[DB00480 DB01606] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A8;SLC22A6 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 39680:[DB00480 DB03191] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03191|3-Oxiran-2ylalanine MAT1A common genes common pathways 39681:[DB00480 DB06909] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06909|1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide PDE4B common genes common pathways 39682:[DB00480 DB00481] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;TFF1;CDH5 GO:0030154| cell differentiation TFF1;TNFSF11 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SERPINB9;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;ESR1;TNFSF11 GO:0006955| immune response SERPINB9;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0010469| regulation of receptor activity TFF1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;AOX1;CYP3A4;CYP19A1;CYP2B6 GO:0042493| response to drug ABCB1;PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;SERPINB9 39683:[DB00480 DB01536] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;AKR1C3 GO:0055114| oxidation-reduction process HSD3B1;HSD17B1;PTGS2;AKR1C3;CYP3A4 GO:0008284| positive regulation of cell proliferation AKR1C3;PTGS2 GO:0010942| positive regulation of cell death PTGS2;AKR1C3 GO:0019371| cyclooxygenase pathway PTGS2;AKR1C3 GO:0006629| lipid metabolic process CYP3A4;PTGS2;HSD17B1 GO:0006693| prostaglandin metabolic process AKR1C3;PTGS2 39684:[DB00480 DB12095] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12095|Telotristat ethyl TPH2;TPH1 common genes common pathways GO:0060749| mammary gland alveolus development TPH1;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;TPH2;TPH1 GO:0051384| response to glucocorticoid stimulus TPH2;PTGS2 39685:[DB00480 DB03233] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03233|Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester DTYMK common genes common pathways 39686:[DB00480 DB08806] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08806|Roxatidine acetate HRH2 common genes common pathways GO:0006955| immune response HRH2;TNFSF11 GO:0045907| positive regulation of vasoconstriction HRH2;PTGS2 GO:0007613| memory PTGS2;HRH2 39687:[DB00480 DB12498] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;CXCR4 GO:0006954| inflammatory response CXCR4;PTGS2 39688:[DB00480 DB07388] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07388|ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2;NOS3 common genes common pathways GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0001525| angiogenesis NOS3;PTGS2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process NOS3;PTGS2;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 39689:[DB00480 DB00827] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00827|Cinoxacin gyrA;CYP1A2;SLC22A6 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0055085| transmembrane transport SLC22A6;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 39690:[DB00480 DB11967] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;UGT1A1;PTGS2 GO:0002548| monocyte chemotaxis TNFSF11;IL6 GO:0030316| osteoclast differentiation TNF;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP1A2 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2;IL6 GO:0019221| cytokine-mediated signaling pathway IL1B;IL6;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0042127| regulation of cell proliferation TNF;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;UGT1A1;CYP1A2;IL1B GO:0046330| positive regulation of JNK cascade TNF;TNFSF11;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL1B;IL6;TNF GO:0008284| positive regulation of cell proliferation IL6;IL1B;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;IL6 GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0010033| response to organic substance UGT1A1;TNF;PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0010469| regulation of receptor activity TNFSF11;IL6;IL1B;TNF GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IL1B;IL6;TNF GO:0070371| ERK1 and ERK2 cascade MAP2K2;TNFSF11 GO:0006954| inflammatory response TNF;PTGS2;IL1B;IL6 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;IL1B;IL6;TNFSF11 GO:0006955| immune response TNF;IL6;IL1B;TNFSF11 GO:0010575| positive regulation vascular endothelial growth factor production IL1B;PTGS2 GO:0031622| positive regulation of fever generation TNF;PTGS2;IL1B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;IL1B;TNF GO:0007275| multicellular organismal development TNFSF11;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0043065| positive regulation of apoptotic process TNF;PTGS2;IL6 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B;MAP3K1 GO:0014070| response to organic cyclic compound CYP1A2;UGT1A1;PTGS2 GO:0008285| negative regulation of cell proliferation IL6;IL1B;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus IL6;PTGS2;TNF;UGT1A1 GO:0007566| embryo implantation IL1B;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation IL6;TNF;PTGS2 39691:[DB00480 DB00629] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 39692:[DB00480 DB01632] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways 39693:[DB00480 DB04071] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04071|Cpad ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 39694:[DB00480 DB02821] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02821|Canaline OAT common genes common pathways 39695:[DB00480 DB05812] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes common pathways GO:0006810| transport ABCC1;ABCB1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0098869| ALB;PTGS2 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP1A2;CYP3A4;CYP17A1;CYP2C8;CYP2C19;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP1A2;SULT2A1;CYP3A4;PTGS2 GO:0006954| inflammatory response ORM1;PTGS2 39696:[DB00480 DB01370] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01370|Aluminium TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0046330| positive regulation of JNK cascade TNFSF11;APP GO:0007612| learning APP;PTGS2 GO:0007155| cell adhesion CDH5;APP GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;APP GO:0042493| response to drug ABCB1;ATP1A1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade APP;TNFSF11 GO:0006979| response to oxidative stress APP;PTGS2 GO:0098869| PTGS2;ALB GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;APP GO:0051260| protein homooligomerization APP;TNFSF11 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;APP GO:0007613| memory PTGS2;APP GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;APP GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;APP;CDH5 39697:[DB00480 DB04818] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04818|Iproniazid MAOB;CYP2D6;CYP2C9 common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0042493| response to drug MAOB;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP2C9;CYP2D6;PTGS2;MAOB GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP2C9 39698:[DB00480 DB00889] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00889|Granisetron HTR3A;CYP3A4;CYP1A1 common genes common pathways GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0007568| aging CYP1A1;PTGS2 GO:0042493| response to drug ABCB1;CYP1A1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A1;CYP3A4 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39699:[DB00480 DB02207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02207|7-Nitroindazole NOS3;NOS2 common genes common pathways GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process NOS3;PTGS2;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0001525| angiogenesis NOS3;PTGS2 39700:[DB00480 DB01114] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory PTGS2;SLC6A4;HRH1 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0051260| protein homooligomerization SLC22A1;SLC6A4;TNFSF11 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0007568| aging PTGS2;SLC6A3 GO:0006810| transport ABCB1;SLC6A2 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0055085| transmembrane transport ABCB1;SLC22A1;SLC6A4;SLC6A3;SLC22A2;SLC6A2 GO:0042493| response to drug SLC6A4;ABCB1;SLC6A3;PTGS2;SLC6A2 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP3A5;CYP3A4;CYP2D6 39701:[DB00480 DB03731] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03731|S-2-(Boronoethyl)-L-Cysteine ARG1;ARG2 common genes common pathways GO:0042493| response to drug PTGS2;ARG1;ABCB1 GO:0010042| response to manganese ion ARG1;PTGS2 GO:0032496| response to lipopolysaccharide ARG1;PTGS2 GO:0007568| aging PTGS2;ARG1 39702:[DB00480 DB11294] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11294|Coccidioides immitis spherule HLA-A;HLA-A;HLA-B common genes common pathways GO:0006955| immune response HLA-B;TNFSF11;HLA-A 39703:[DB00480 DB08800] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08800|Chloropyramine HRH1 common genes common pathways GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory PTGS2;HRH1 GO:0006954| inflammatory response HRH1;PTGS2 39704:[DB00480 DB07239] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07239|7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion DPP4;CDH5 39705:[DB00480 DB08384] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08384|2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline PDE10A common genes common pathways 39706:[DB00480 DB05398] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05398|C31G CD9 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;CD9;CDH5 GO:0007155| cell adhesion CD9;CDH5 39707:[DB00480 DB01277] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways GO:0043065| positive regulation of apoptotic process IGFBP3;IGF2R;PTGS2 GO:0006955| immune response TNFSF11;IGF1R GO:0007613| memory PTGS2;INSR GO:0008285| negative regulation of cell proliferation CDH5;IGFBP3;PTGS2 GO:0008284| positive regulation of cell proliferation IGF1R;PTGS2;INSR GO:0043066| negative regulation of apoptotic process IGF1R;PTGS2 GO:0007612| learning PTGS2;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process INSR;PTGS2 GO:0009887| organ morphogenesis TNFSF11;INSR 39708:[DB00480 DB02746] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0007566| embryo implantation PPARD;RXRA;PTGS2 GO:0030154| cell differentiation TNFSF11;PPARD GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0038001| paracrine signaling TNFSF11;PGR GO:0006629| lipid metabolic process PTGS2;PPARD;PPARA;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;PPARG;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0071456| cellular response to hypoxia PTGS2;PPARD GO:0046697| decidualization PPARD;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG;PPARD GO:0055085| transmembrane transport ABCB1;SLCO2B1 GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRG;PGR;TNFSF11;RXRB;ESR1;PPARA;ESR2;PPARG;RXRA GO:0043066| negative regulation of apoptotic process PTGS2;PPARD GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;PPARD GO:0050728| negative regulation of inflammatory response PPARD;PPARA;CDH5 GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0006631| fatty acid metabolic process PPARA;PTGS2 39709:[DB00480 DB02175] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02175|Malonic acid panD;SRC;SNRPA common genes common pathways GO:0098609| SRC;CDH5 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:1902533| TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0034332| adherens junction organization CDH5;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0070542| response to fatty acid SRC;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC 39710:[DB00480 DB02118] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02118|CP-271485 MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 39711:[DB00480 DB00892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00892|Oxybuprocaine SCN10A;BCHE common genes common pathways GO:0019233| sensory perception of pain SCN10A;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug PTGS2;BCHE;ABCB1 GO:0055085| transmembrane transport ABCB1;SCN10A 39712:[DB00480 DB02558] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02558|N-(3-Phenyl-2-Sulfanylpropanoyl)Phenylalanylalanine MME common genes common pathways GO:0019233| sensory perception of pain PTGS2;MME 39713:[DB00480 DB08530] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08530|7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 39714:[DB00480 DB13925] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13925|Dotatate gallium Ga-68 SSTR2 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;SSTR2;PTGS2 39715:[DB00480 DB07468] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07468|(3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one MYH14 common genes common pathways 39716:[DB00480 DB01180] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01180|Rescinnamine ACE common genes common pathways GO:0008217| regulation of blood pressure ACE;PTGS2 39717:[DB00480 DB00216] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2B GO:0006810| transport ABCB1 GO:0098869| PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP2A6;CYP3A4;PTGS1;PTGS2;CYP2C19 GO:0099040| ABCB1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0042493| response to drug HTR1B;ABCB1;HTR2B;PTGS2 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2B;HTR1A;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0072089| stem cell proliferation ABCB1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;CYP2D6;CYP3A4 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 39718:[DB00480 DB02170] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02170|1,8-Di-Hydroxy-4-Nitro-Xanthen-9-One CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0008284| positive regulation of cell proliferation CSNK2A1;PTGS2 39719:[DB00480 DB00913] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00913|Anileridine OPRM1 common genes common pathways GO:0009314| response to radiation OPRM1;PTGS2 GO:0019233| sensory perception of pain PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 39720:[DB00480 DB08848] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08848|Guvacine SLC6A13;SLC6A1;SLC6A11;SLC6A12 common genes common pathways GO:0014070| response to organic cyclic compound SLC6A1;PTGS2 GO:0010243| response to organic nitrogen SLC6A1;PTGS2 GO:0042493| response to drug PTGS2;SLC6A11;ABCB1 GO:0007612| learning PTGS2;SLC6A1 GO:0010033| response to organic substance PTGS2;SLC6A1 GO:0055085| transmembrane transport SLC6A1;SLC6A13;SLC6A12;ABCB1;SLC6A11 GO:0051260| protein homooligomerization SLC6A1;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;SLC6A1 GO:0006810| transport SLC6A1;ABCB1;SLC6A12 39721:[DB00480 DB04854] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04854|Febuxostat XDH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;XDH 39722:[DB00480 DB00528] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways GO:0006810| transport ABCB1;CACNG1 GO:0055114| oxidation-reduction process CYP3A5;CYP3A7;PTGS2;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 39723:[DB00480 DB12537] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12537|Benzodiazepine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39724:[DB00480 DB02512] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02512|1,6-Fructose Diphosphate (Linear Form) ALDOA;ALDOB common genes common pathways 39725:[DB00480 DB12589] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12589|Dacetuzumab CD40 common genes common pathways GO:0071260| cellular response to mechanical stimulus CD40;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CD40 GO:0007275| multicellular organismal development CD40;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity CD40;TNFSF11 GO:0006954| inflammatory response CD40;PTGS2 GO:0006955| immune response TNFSF11;CD40 GO:0033209| tumor necrosis factor-mediated signaling pathway CD40;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;CD40 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;CD40 GO:0042127| regulation of cell proliferation CD40;PTGS2 GO:0032496| response to lipopolysaccharide CD40;PTGS2 39726:[DB00480 DB01012] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01012|Cinacalcet CASR;CYP3A4;CYP2D6;CYP1A2 common genes common pathways GO:0045907| positive regulation of vasoconstriction CASR;PTGS2 GO:0014070| response to organic cyclic compound CASR;PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP1A2;CYP3A4 GO:0001503| ossification CASR;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;CASR GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0008284| positive regulation of cell proliferation CASR;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 39727:[DB00480 DB07106] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07106|4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE HNMT common genes common pathways 39728:[DB00480 DB09097] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09097|Quinagolide DRD2;DRD1;DRD5 common genes common pathways GO:0042493| response to drug PTGS2;DRD2;DRD1;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0007612| learning DRD1;PTGS2;DRD5 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0007613| memory DRD1;PTGS2 39729:[DB00480 DB08629] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08629|N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE ATP5B common genes common pathways GO:0001525| angiogenesis ATP5B;PTGS2 GO:0006629| lipid metabolic process ATP5B;PTGS2 39730:[DB00480 DB04886] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04886|Calanolide A CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39731:[DB00480 DB01132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01132|Pioglitazone PPARG;PPARD;PPARA;MAOB;CYP2C8;CYP3A4;PTGS1;CYP2C9;SLCO1B3;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;CYP3A4;PPARA;PPARD;PPARG;PTGS1;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0030154| cell differentiation TNFSF11;PPARD GO:0007566| embryo implantation PPARD;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG;PPARA GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0043066| negative regulation of apoptotic process PPARD;PTGS2 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;MAOB;PTGS1;CYP2C8;PTGS2 GO:0042493| response to drug ABCB1;PPARG;MAOB;PTGS2 GO:0006631| fatty acid metabolic process PPARA;PTGS1;PTGS2 GO:0050728| negative regulation of inflammatory response PPARA;PPARD;CDH5 GO:0071456| cellular response to hypoxia PTGS2;PPARD GO:0046697| decidualization PPARD;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0098869| PTGS1;PTGS2 GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLCO1B1 GO:0010033| response to organic substance PPARG;PPARD;PTGS2 39732:[DB00480 DB05075] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4 GO:0007275| multicellular organismal development TNFSF11;KDR;FLT1 GO:0001525| angiogenesis FLT1;PTGS2;FLT4;KDR GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;CSK GO:0030154| cell differentiation KDR;FLT1;TNFSF11;CSK GO:0034332| adherens junction organization CSK;CDH5 GO:0002548| monocyte chemotaxis FLT1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;FLT4;KDR GO:0008284| positive regulation of cell proliferation PTGS2;KDR;FLT4;FLT1 GO:0042127| regulation of cell proliferation PTGS2;CSK GO:0046330| positive regulation of JNK cascade FLT4;TNFSF11 GO:0043406| positive regulation of MAP kinase activity CSK;TNFSF11;FLT1 39733:[DB00480 DB04736] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04736|2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINE PGLYRP3 common genes common pathways 39734:[DB00480 DB05364] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05364|ROX-888 CCL3 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;CCL3 GO:0006954| inflammatory response PTGS2;CCL3 GO:0006955| immune response CCL3;TNFSF11 GO:0010469| regulation of receptor activity CCL3;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;CCL3 GO:0002548| monocyte chemotaxis TNFSF11;CCL3 39735:[DB00480 DB00067] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0045907| positive regulation of vasoconstriction AVPR2;AVPR1A;AVPR1B;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;AVPR1A GO:0031394| positive regulation of prostaglandin biosynthetic process AVPR1A;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCC2 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0006810| transport ABCC2;ABCB1 GO:0010033| response to organic substance PTGS2;AVPR1A GO:0055085| transmembrane transport ABCB1;ABCC2 GO:0008284| positive regulation of cell proliferation PTGS2;AVPR2;AVPR1A GO:0034097| response to cytokine stimulus PTGS2;AVPR2 GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:0042493| response to drug PTGS2;ABCB1;ABCC2 39736:[DB00480 DB03216] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03216|(1'R,2'S)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-yl)Adenine AHCY common genes common pathways 39737:[DB00480 DB00983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0007568| aging PTGS2;ADRB3 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP2D6;CYP2C9;CYP2A6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP2C9 GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB3;ADRB2 39738:[DB00480 DB05204] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05204|XL418 BTK common genes common pathways GO:0010033| response to organic substance BTK;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;BTK GO:0019722| calcium-mediated signaling BTK;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity BTK;TNFSF11 39739:[DB00480 DB02902] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways 39740:[DB00480 DB07116] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07116|1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-4-METHYL-1H-INDOLE UNG common genes common pathways GO:0043066| negative regulation of apoptotic process UNG;PTGS2 39741:[DB00480 DB07646] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07646|UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE B1;DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0042493| response to drug ABCB1;PTGS2;DHODH GO:0055114| oxidation-reduction process DHODH;PTGS2 39742:[DB00480 DB04599] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006810| transport GRIA3;ABCB1 GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0042493| response to drug ABCB1;DRD2;HTR2A;PTGS2 39743:[DB00480 DB01667] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01667|8-azaguanine PNP;CYP1A2 common genes common pathways GO:0006955| immune response TNFSF11;PNP GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;PNP;ABCB1;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 39744:[DB00480 DB06831] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06831|2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE PIK3CG;PIK3CD common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CG;PIK3CD;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;PIK3CG GO:0001525| angiogenesis PTGS2;PIK3CG GO:0006954| inflammatory response PTGS2;PIK3CG;PIK3CD GO:0030154| cell differentiation PIK3CD;TNFSF11 39745:[DB00480 DB00935] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0045907| positive regulation of vasoconstriction ADRA2C;ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;ADRA1B;PTGS2 GO:0007275| multicellular organismal development ADRA1D;TNFSF11;ADRA1B GO:0007568| aging PTGS2;ADRA1A GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0008284| positive regulation of cell proliferation PTGS2;ADRA2A;ADRA1D GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A 39746:[DB00480 DB05016] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05016|Ataluren SLC22A6;SLC22A8;SLCO1B3 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLC22A6;SLC22A8 39747:[DB00480 DB01341] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways GO:0006810| transport ABCB1;GABRA1 39748:[DB00480 DB02183] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02183|Adenosine-5'-Ditungstate HINT1 common genes common pathways 39749:[DB00480 DB00129] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00129|Ornithine OAT;OTC;ARG1;OAZ1;SLC7A2;SLC25A2;SLC7A4;SLC7A1;ARG2;SLC25A15;SLC7A3;OAZ2;GATM;OAZ3 common genes common pathways GO:0050727| regulation of inflammatory response SLC7A2;PTGS2 GO:0007275| multicellular organismal development GATM;TNFSF11 GO:0010042| response to manganese ion PTGS2;ARG1 GO:0042493| response to drug PTGS2;ARG1;OTC;ABCB1 GO:0032496| response to lipopolysaccharide ARG1;PTGS2 GO:0007568| aging PTGS2;ARG1 GO:0006810| transport SLC7A2;ABCB1;SLC7A1;SLC7A4 39750:[DB00480 DB05467] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05467|R667 RARG common genes common pathways GO:1990830| RARG;TNFSF11 GO:0008284| positive regulation of cell proliferation RARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RARG GO:0043066| negative regulation of apoptotic process PTGS2;RARG GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;RARG GO:0043065| positive regulation of apoptotic process PTGS2;RARG 39751:[DB00480 DB00519] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00519|Trandolapril ACE;CES1;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0008217| regulation of blood pressure ACE;PTGS2 39752:[DB00480 DB09274] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39753:[DB00480 DB03397] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03397|Uridine-Diphosphate-N-Acetylglucosamine glmU;UAP1;murA;GALE;glmU;EXTL2;MGAT1 common genes common pathways 39754:[DB00480 DB01908] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01908|RU85493 SRC common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug ABCB1;PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| SRC;CDH5 GO:1902533| SRC;TNFSF11 39755:[DB00480 DB11919] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11919|6-O-benzylguanine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 39756:[DB00480 DB06962] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06962|(5-(aminomethyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)(5-(phenylethynyl)furan-2-yl)methanone TPSB2 common genes common pathways 39757:[DB00480 DB06928] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06928|(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACID FOLH1 common genes common pathways 39758:[DB00480 DB06376] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06376|CHGN111 CLK1 common genes common pathways 39759:[DB00480 DB11273] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11273|Dihydroergocornine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4 common genes common pathways GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0007613| memory PTGS2;HTR2A GO:0045453| bone resorption TNFSF11;ADRB2 GO:0045907| positive regulation of vasoconstriction ADRA2C;ADRA1D;ADRA1A;HTR2A;PTGS2;ADRA1B GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;PTGS2;ADRA1B GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;PTGS2 GO:0050873| brown fat cell differentiation ADRB3;PTGS2;ADRB1;ADRB2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0007568| aging HTR2A;ADRA1A;ADRB3;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11;HTR2A;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HTR2B;HTR2A;ADRA1D;ADRA2A GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0042493| response to drug HTR2A;ADRA1A;PTGS2;HTR2B;HTR2C;ABCB1;HTR1B GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 39760:[DB00480 DB12248] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12248|Tulobuterol ADRB2 common genes common pathways GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 39761:[DB00480 DB02518] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02518|N-Acetylalanine AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 39762:[DB00480 DB11575] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes ABCB1 common pathways GO:0098869| ALB;PTGS2 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1B1;ABCB1;SLCO1B3 GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:1901529| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006954| inflammatory response PTGS2;ORM1 39763:[DB00480 DB01084] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01084|Emedastine HRH1 common genes common pathways GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 39764:[DB00480 DB02759] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02759|4-Methylumbelliferyl Chitobiose LYZ common genes common pathways GO:0006954| inflammatory response PTGS2;LYZ 39765:[DB00480 DB11327] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11327|Dipyrithione NOS2;PTGS2 common genes PTGS2 common pathways GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0006954| inflammatory response PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0034605| cellular response to heat PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process NOS2;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 GO:0007612| learning PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034097| response to cytokine stimulus PTGS2 39766:[DB00480 DB14542] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0051384| response to glucocorticoid stimulus ANXA1;HSD11B2;PTGS2 GO:0072089| stem cell proliferation ABCB1 GO:0008217| regulation of blood pressure CYP11B1;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process ANXA1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0014070| response to organic cyclic compound PTGS2;ANXA1 GO:0006629| lipid metabolic process CYP3A4;CYP11B1;PTGS2;CYP11B2 GO:0043065| positive regulation of apoptotic process ANXA1;PTGS2 GO:0050727| regulation of inflammatory response ANXA1;PTGS2 GO:0006955| immune response CYP11B1;TNFSF11 GO:0006954| inflammatory response PTGS2;ANXA1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;PTGS2 GO:0006810| transport ABCB1;ABCG2 GO:0098609| ANXA1;CDH5 GO:0032355| response to estradiol stimulus ANXA1;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1A2;ABCG2;SLC22A8;ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:0042127| regulation of cell proliferation ANXA1;PTGS2 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A4;HSD11B2;CYP2C8;CYP11B2;PTGS2;HSD3B1;CYP3A5;CYP11B1;CYP3A7 GO:0099040| ABCB1 GO:0002548| monocyte chemotaxis ANXA1;TNFSF11 GO:0042493| response to drug ABCG2;PTGS2;ABCB1;HSD11B2;ANXA1 39767:[DB00480 DB06083] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06083|Tapinarof IL12B;IL2;IL6;CXCL8 common genes common pathways GO:0010033| response to organic substance IL12B;PTGS2 GO:0010469| regulation of receptor activity IL6;TNFSF11;IL2;CXCL8;IL12B GO:0002548| monocyte chemotaxis TNFSF11;IL6 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL6 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;IL6 GO:0050728| negative regulation of inflammatory response IL2;CDH5 GO:0007155| cell adhesion CDH5;IL2 GO:0043066| negative regulation of apoptotic process PTGS2;IL6;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL2;IL6 GO:0008284| positive regulation of cell proliferation IL2;IL6;PTGS2 GO:0008285| negative regulation of cell proliferation CXCL8;CDH5;IL6;PTGS2 GO:0019722| calcium-mediated signaling CXCL8;TNFSF11 GO:0051384| response to glucocorticoid stimulus PTGS2;IL6 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;IL6 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;IL6 GO:0006955| immune response CXCL8;IL2;TNFSF11;IL6 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IL6 GO:0006954| inflammatory response CXCL8;IL6;PTGS2 GO:0019233| sensory perception of pain IL12B;PTGS2 GO:0001525| angiogenesis PTGS2;CXCL8 GO:0045672| positive regulation of osteoclast differentiation IL12B;TNFSF11 GO:0043065| positive regulation of apoptotic process IL6;PTGS2 39768:[DB00480 DB07288] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07288|N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide FLT1 common genes common pathways GO:0002548| monocyte chemotaxis TNFSF11;FLT1 GO:0008284| positive regulation of cell proliferation PTGS2;FLT1 GO:0043406| positive regulation of MAP kinase activity FLT1;TNFSF11 GO:0001525| angiogenesis PTGS2;FLT1 GO:0007275| multicellular organismal development FLT1;TNFSF11 GO:0030154| cell differentiation TNFSF11;FLT1 39769:[DB00480 DB11574] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes ABCB1 common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP3A43;PTGS2;CYP3A5;CYP3A7 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 39770:[DB00480 DB02445] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02445|2-Deoxy-2-Amino Glucitol-6-Phosphate GNPDA1;glmS common genes common pathways 39771:[DB00480 DB05212] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NFKB2;NFKB1 GO:0043066| negative regulation of apoptotic process NFKB1;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;NFKB2 GO:0032496| response to lipopolysaccharide PTGS2;NFKB2 GO:0050728| negative regulation of inflammatory response CDH5;NFKB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0007568| aging PTGS2;NFKB2 GO:0071260| cellular response to mechanical stimulus PTGS2;NFKB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006954| inflammatory response NFKB2;PTGS2;NFKB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;NFKB1;NFKB2 39772:[DB00480 DB05944] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05944|Varlitinib ERBB2;EGFR common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;EGFR GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0001503| ossification EGFR;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0043406| positive regulation of MAP kinase activity ERBB2;EGFR;TNFSF11 GO:0006979| response to oxidative stress PTGS2;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0098609| EGFR;CDH5 GO:0032355| response to estradiol stimulus PTGS2;EGFR GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;ERBB2;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0008284| positive regulation of cell proliferation EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS2 39773:[DB00480 DB05009] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05009|Apadenoson ADORA2A common genes common pathways GO:0006954| inflammatory response ADORA2A;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADORA2A GO:0050728| negative regulation of inflammatory response ADORA2A;CDH5 GO:0042493| response to drug ADORA2A;PTGS2;ABCB1 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 39774:[DB00480 DB12518] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12518|Raclopride DRD2 common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2 39775:[DB00480 DB05281] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0042493| response to drug BCL2;ABCB1;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;BCL2 GO:0008284| positive regulation of cell proliferation BCL2;PTGS2 GO:0043066| negative regulation of apoptotic process BCL2;PTGS2 GO:0055085| transmembrane transport ABCB1;BCL2 GO:0000086| G2/M transition of mitotic cell cycle TUBA4A;ABCB1 GO:0009887| organ morphogenesis BCL2;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;BCL2 GO:0098609| BCL2;CDH5 GO:0006979| response to oxidative stress PTGS2;BCL2 GO:0001503| ossification TNFSF11;BCL2 GO:0009314| response to radiation PTGS2;BCL2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCL2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation BCL2;PTGS2 39776:[DB00480 DB11311] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11311|Prothrombin FGA;FGB;F13A1;CPB2;F10 common genes common pathways GO:0042493| response to drug CPB2;PTGS2;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 GO:0045907| positive regulation of vasoconstriction FGA;PTGS2;FGB 39777:[DB00480 DB08391] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08391|6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 39778:[DB00480 DB07775] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07775|3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0010469| regulation of receptor activity TTR;TNFSF11 39779:[DB00480 DB06439] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06439|Tyloxapol LPL common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS2;LPL GO:0006629| lipid metabolic process PTGS2;LPL GO:0042493| response to drug ABCB1;LPL;PTGS2 39780:[DB00480 DB12702] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12702|Velusetrag HTR4 common genes common pathways 39781:[DB00480 DB03554] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03554|5-Iodouracil DPYD common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DPYD 39782:[DB00480 DB08473] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08473|5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 39783:[DB00480 DB04356] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 39784:[DB00480 DB08056] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08056|N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine LCK common genes common pathways GO:0050870| positive regulation of T cell activation TNFSF11;LCK GO:0042127| regulation of cell proliferation PTGS2;LCK GO:0042493| response to drug PTGS2;LCK;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;LCK 39785:[DB00480 DB07124] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07124|(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE PRKACA common genes common pathways GO:0034605| cellular response to heat PRKACA;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle PRKACA;ABCB1 39786:[DB00480 DB00376] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00376|Trihexyphenidyl CHRM1;CHRM2;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 39787:[DB00480 DB00901] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00901|Bitolterol ADRB2 common genes common pathways GO:0050873| brown fat cell differentiation ADRB2;PTGS2 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 39788:[DB00480 DB07167] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07167|5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE CSF1R common genes common pathways GO:0030316| osteoclast differentiation TNFSF11;CSF1R GO:0019221| cytokine-mediated signaling pathway TNFSF11;CSF1R GO:0008284| positive regulation of cell proliferation PTGS2;CSF1R GO:0043066| negative regulation of apoptotic process CSF1R;PTGS2 GO:0006954| inflammatory response PTGS2;CSF1R GO:0007275| multicellular organismal development TNFSF11;CSF1R GO:0008285| negative regulation of cell proliferation CDH5;CSF1R;PTGS2 39789:[DB00480 DB01303] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0050728| negative regulation of inflammatory response ADORA2A;ADORA1;CDH5 GO:0042493| response to drug CYP1A2;ABCB1;PDE3A;ADORA2A;PTGS2;HDAC2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0043066| negative regulation of apoptotic process ADORA1;PDE3A;PTGS2;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;HDAC2 GO:0032496| response to lipopolysaccharide HDAC2;PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC22A7 GO:0034605| cellular response to heat HDAC2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0097756| PTGS2;ADORA1 GO:0006954| inflammatory response PTGS2;ADORA2A;ADORA1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2;PDE3A GO:0008285| negative regulation of cell proliferation CDH5;ADORA1;ADORA2A;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 39790:[DB00480 DB08341] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;PTK2B;CDH5 GO:0010226| response to lithium ion PTGS2;PTK2B GO:0030154| cell differentiation TNFSF11;PTK2B GO:0045453| bone resorption PTK2B;TNFSF11 GO:0071498| cellular response to fluid shear stress PTK2B;PTGS2 GO:0001525| angiogenesis PTGS2;PTK2B GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;PTK2B GO:0033209| tumor necrosis factor-mediated signaling pathway PTK2B;TNFSF11 GO:2000114| regulation of establishment of cell polarity PTK2B;CDH5 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;PTK2B GO:0042493| response to drug PTK2B;PTGS2;ABCB1 GO:0010243| response to organic nitrogen PTGS2;PTK2B GO:0042127| regulation of cell proliferation PTGS2;PTK2B GO:0046330| positive regulation of JNK cascade PTK2B;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;PTK2B GO:0043066| negative regulation of apoptotic process PTGS2;PTK2B GO:0007155| cell adhesion CDH5;PTK2B 39791:[DB00480 DB13627] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13627|Oxolinic acid CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 39792:[DB00480 DB05036] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05036|Grn163l SMG6;SCYL1;PTGES3;TERT common genes common pathways GO:0043066| negative regulation of apoptotic process TERT;PTGS2 GO:0006631| fatty acid metabolic process PTGES3;PTGS2 GO:0071456| cellular response to hypoxia TERT;PTGS2 GO:0006629| lipid metabolic process PTGES3;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;PTGES3 GO:0006693| prostaglandin metabolic process PTGES3;PTGS2 GO:0019371| cyclooxygenase pathway PTGES3;PTGS2 GO:0006633| fatty acid biosynthetic process PTGES3;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGES3 39793:[DB00480 DB07969] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07969|3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET 39794:[DB00480 DB03902] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03902|Oxalic Acid SRC;SLCO2B1;SLC22A8 common genes common pathways GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0055085| transmembrane transport SLC22A8;SLCO2B1;ABCB1 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0045453| bone resorption TNFSF11;SRC 39795:[DB00480 DB04249] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04249|Zinc Substituted Heme C CYCS common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYCS 39796:[DB00480 DB01890] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01890|N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide IGF1;PPARA common genes common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;IGF1 GO:0006629| lipid metabolic process PTGS2;PPARA GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;IGF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA;IGF1 GO:0008284| positive regulation of cell proliferation PTGS2;IGF1 GO:0043066| negative regulation of apoptotic process PTGS2;IGF1 GO:0010469| regulation of receptor activity IGF1;TNFSF11 39797:[DB00480 DB08237] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08237|2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) POLK common genes common pathways GO:0034644| cellular response to UV POLK;PTGS2 39798:[DB00480 DB14014] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14014|SR-9011 NR1D2;NR1D1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;NR1D2 GO:0030154| cell differentiation TNFSF11;NR1D1 39799:[DB00480 DB00535] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0055085| transmembrane transport SLC22A5;SLC15A2;SLC22A8;SLC22A6;SLC15A1;ABCB1 GO:0006979| response to oxidative stress PTGS2;MPO GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006810| transport SLC15A1;ABCB1;SLC15A2 GO:0007568| aging PTGS2;MPO GO:0055114| oxidation-reduction process MPO;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;MPO GO:0032496| response to lipopolysaccharide MPO;PTGS2 39800:[DB00480 DB05070] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05070|ADX10059 GRM5 common genes common pathways GO:0007612| learning GRM5;PTGS2 39801:[DB00480 DB05481] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05481|Recombinant alpha 1-antitrypsin SERPINA1 common genes common pathways 39802:[DB00480 DB13456] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13456|Midecamycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 39803:[DB00480 DB14520] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14520|Tetraferric tricitrate decahydrate TFRC;TF;ITGB3;CALR common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;CALR GO:0045780| positive regulation of bone resorption TNFSF11;TFRC GO:0010033| response to organic substance PTGS2;CALR GO:1990830| TNFSF11;TFRC GO:0042127| regulation of cell proliferation TFRC;PTGS2 GO:0007155| cell adhesion ITGB3;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;CALR GO:0030316| osteoclast differentiation TFRC;TNFSF11 GO:0042493| response to drug PTGS2;CALR;ABCB1 39804:[DB00480 DB04991] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04991|XL784 ADAM10 common genes common pathways GO:0034612| response to tumor necrosis factor ADAM10;PTGS2 GO:0008284| positive regulation of cell proliferation ADAM10;PTGS2 39805:[DB00480 DB00723] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00723|Methoxamine ADRA1A;ADRA1B;ADRA1D common genes common pathways GO:0045907| positive regulation of vasoconstriction ADRA1D;ADRA1B;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2;ADRA1B;ADRA1D GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;PTGS2 GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0007568| aging PTGS2;ADRA1A GO:0008284| positive regulation of cell proliferation PTGS2;ADRA1D GO:0042493| response to drug ABCB1;ADRA1A;PTGS2 39806:[DB00480 DB11799] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC47A1 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0055085| transmembrane transport ABCB1;SLC47A1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042493| response to drug PTGS2;UGT1A1;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;POU2F2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 39807:[DB00480 DB00025] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00025|Antihemophilic factor, human recombinant F10;F9;VWF;PHYH;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;F2;PROC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 GO:0050728| negative regulation of inflammatory response CDH5;PROC GO:0055114| oxidation-reduction process PHYH;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PHYH GO:0042493| response to drug ABCB1;PTGS2;CALR GO:0007155| cell adhesion VWF;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;HSPA5;PROC GO:0008284| positive regulation of cell proliferation F2;CALR;PTGS2 GO:0010033| response to organic substance CALR;PTGS2 GO:0051260| protein homooligomerization VWF;TNFSF11 GO:0007568| aging PTGS2;CANX;LRP1 GO:0030282| bone mineralization PTGS2;ASGR2 GO:0032355| response to estradiol stimulus PTGS2;CALR GO:0010469| regulation of receptor activity TNFSF11;F2 GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0006629| lipid metabolic process LRP1;PTGS2 GO:0009314| response to radiation HSPA5;PTGS2 GO:0007275| multicellular organismal development TNFSF11;LRP1;F2 GO:1903142| CDH5;PROC 39808:[DB00480 DB07086] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07086|4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL NCOA2;ESR1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 39809:[DB00480 DB12329] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;MAOA;CYP3A4 39810:[DB00480 DB01365] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1;ADRB3 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA1D;ADRA2C;ADRA1B;PTGS2;ADRA1A GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0008284| positive regulation of cell proliferation PTGS2;ADRA2A;ADRA1D GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0007568| aging ADRB3;ADRA1A;PTGS2 39811:[DB00480 DB02644] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02644|N-Omega-Propyl-L-Arginine NOS2;NOS1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;NOS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;TNFSF11 GO:0051926| negative regulation of calcium ion transport NOS1;PTGS2 GO:0055114| oxidation-reduction process NOS2;PTGS2;NOS1 39812:[DB00480 DB07853] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07853|[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE SLK;CAMK2D;STK26 common genes common pathways GO:0030154| cell differentiation CAMK2D;TNFSF11 39813:[DB00480 DB05085] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05085|TM30339 NPY4R common genes common pathways 39814:[DB00480 DB09211] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09211|Limaprost PTGER1;PTGER2;PTGER3;PTGER4 common genes common pathways GO:0050728| negative regulation of inflammatory response CDH5;PTGER4 GO:0042127| regulation of cell proliferation PTGER2;PTGS2 GO:0032496| response to lipopolysaccharide PTGER4;PTGER2;PTGER1;PTGS2 GO:0006955| immune response TNFSF11;PTGER4 GO:0070371| ERK1 and ERK2 cascade PTGER4;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2;PTGER3 GO:0071260| cellular response to mechanical stimulus PTGER4;PTGS2 39815:[DB00480 DB00219] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00219|Oxyphenonium CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 39816:[DB00480 DB13928] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS2;LPL GO:0019233| sensory perception of pain MME;PTGS2 GO:0006629| lipid metabolic process PTGS2;LPL GO:0098869| ALB;PTGS2 GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1B1 GO:0007155| cell adhesion CDH5;DPP4 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0042493| response to drug PTGS2;LPL;ABCB1 39817:[DB00480 DB06771] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06771|Besifloxacin parC;parC;gyrA;gyrA;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 39818:[DB00480 DB03347] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03347|Triethyl Phosphate TP53 common genes common pathways GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;TP53 GO:0006979| response to oxidative stress PTGS2;TP53 GO:0007568| aging TP53;PTGS2 GO:0071456| cellular response to hypoxia TP53;PTGS2 GO:0034605| cellular response to heat TP53;PTGS2 GO:0010243| response to organic nitrogen PTGS2;TP53 GO:0042493| response to drug PTGS2;TP53;ABCB1 GO:0034097| response to cytokine stimulus TP53;PTGS2 GO:0043066| negative regulation of apoptotic process TP53;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TP53;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;TP53 GO:0014070| response to organic cyclic compound TP53;PTGS2 GO:0034644| cellular response to UV TP53;PTGS2 GO:0030154| cell differentiation TNFSF11;TP53 GO:0043065| positive regulation of apoptotic process TP53;PTGS2 GO:0007275| multicellular organismal development TNFSF11;TP53 39819:[DB00480 DB05146] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05146|XL820 KDR;KIT;PDGFRA;PDGFRB common genes common pathways GO:0043406| positive regulation of MAP kinase activity KIT;PDGFRB;TNFSF11 GO:0007568| aging PDGFRB;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;PDGFRB GO:0019221| cytokine-mediated signaling pathway KIT;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade KIT;PDGFRA;PDGFRB;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PDGFRB GO:0042127| regulation of cell proliferation KIT;PTGS2 GO:0008284| positive regulation of cell proliferation PDGFRB;PTGS2;KIT;KDR;PDGFRA GO:0043066| negative regulation of apoptotic process KDR;PTGS2;PDGFRB GO:0014070| response to organic cyclic compound PTGS2;PDGFRB GO:0030154| cell differentiation TNFSF11;KDR GO:0006954| inflammatory response PTGS2;KIT GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;TNFSF11 GO:0001525| angiogenesis PTGS2;KDR GO:0007275| multicellular organismal development PDGFRB;TNFSF11;KDR;PDGFRA GO:0009314| response to radiation PTGS2;KIT GO:0043065| positive regulation of apoptotic process PDGFRB;PTGS2 39820:[DB00480 DB01152] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01152|Candicidin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39821:[DB00480 DB00313] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes common pathways GO:0007566| embryo implantation PTGS2;PPARD GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PPARG;CYP1A2;PTGS2;UGT1A1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 GO:0008217| regulation of blood pressure PPARG;PTGS1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0019233| sensory perception of pain SCN10A;PTGS2;SCN3B;SCN9A GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;ACADSB;UGT2B7;PTGS1;PPARG;CYP3A4;PPARA;PPARD;CYP2C9;CYP1A2;SLC16A1 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis HDAC9;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0006954| inflammatory response PTGS2;SCN9A;HDAC9;PTGS1 GO:0034605| cellular response to heat PTGS2;HDAC2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0046697| decidualization PTGS2;PPARD GO:0007568| aging ABAT;PTGS2 GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2;ALB GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0055085| transmembrane transport SLC22A7;SCN1A;SLC22A5;SLC22A8;SCN9A;SLCO2B1;SCN3A;SLC22A6;SCN5A;SCN4A;SCN10A;SCN7A;SLC16A1;SCN8A;SCN2A;SCN11A;ABCB1 GO:0010033| response to organic substance PPARD;PPARG;CYP1A2;PTGS2;UGT1A1 GO:0032496| response to lipopolysaccharide HDAC2;PTGS2;UGT1A1;CYP1A2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1;PPARD GO:0043066| negative regulation of apoptotic process PTGS2;HDAC2;ALB;PPARD GO:0008284| positive regulation of cell proliferation PTGS2;HDAC2;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA;PPARG;HDAC2 GO:0007155| cell adhesion CDH5;SCN1B GO:0006631| fatty acid metabolic process UGT1A8;PPARA;ACADSB;PTGS1;PTGS2 GO:0042493| response to drug UGT1A1;HDAC2;PTGS2;CYP1A2;ABCB1;ABAT;PPARG;SCN11A GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;ALDH5A1;OGDH;CYP1A2;CYP2B6;CYP2C9;CYP2C18;PTGS2;CYP2C8;CYP2C19;ACADSB;PTGS1;CYP3A5 GO:0050728| negative regulation of inflammatory response CDH5;PPARD;PPARA 39822:[DB00480 DB00354] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2 39823:[DB00480 DB05399] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05399|Succinobucol VCAM1 common genes common pathways GO:0007155| cell adhesion CDH5;VCAM1 GO:0032496| response to lipopolysaccharide VCAM1;PTGS2 GO:0055114| oxidation-reduction process VCAM1;PTGS2 GO:0098609| VCAM1;CDH5 GO:0007568| aging PTGS2;VCAM1 39824:[DB00480 DB07321] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07321|2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE FBP1 common genes common pathways 39825:[DB00480 DB02698] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02698|N-(M-Trifluoromethylphenyl) Phenoxazine-4,6-Dicarboxylic Acid TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport TTR;ABCB1 39826:[DB00480 DB08342] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08342|S-PALMITOYL-L-CYSTEINE TRAPPC6A;TRAPPC3;TRAPPC6B;TRAPPC5;TRAPPC4;TRAPPC1 common genes common pathways 39827:[DB00480 DB02918] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02918|Zardaverine PDE4D common genes common pathways GO:0007568| aging PDE4D;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;PDE4D 39828:[DB00480 DB01752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01752|S-adenosyl-L-homocysteine prmC;PCMT1;PNMT;prmC;PRMT3;HNMT;TRDMT1;GNMT;trmL;PRMT1;cysG;SETD7;trmD;DPH5;trmD;cobA;pcm;COMTD1;GAMT;HNMT common genes common pathways GO:0009887| organ morphogenesis GAMT;TNFSF11 GO:0008284| positive regulation of cell proliferation PRMT1;PTGS2 39829:[DB00480 DB08610] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08610|N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE PDK2 common genes common pathways 39830:[DB00480 DB04379] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04379|N-Methyl-N-(Methylbenzyl)Formamide REN;CYP2E1 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2 GO:0042493| response to drug REN;ABCB1;CYP2E1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;REN GO:0010033| response to organic substance PTGS2;REN GO:0008217| regulation of blood pressure PTGS2;REN 39831:[DB00480 DB01970] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01970|Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide PDE3B common genes common pathways GO:0001525| angiogenesis PTGS2;PDE3B 39832:[DB00480 DB07162] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07162|4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide JAK2 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;JAK2;CDH5 GO:0030154| cell differentiation TNFSF11;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;JAK2 GO:0050727| regulation of inflammatory response PTGS2;JAK2 GO:0043065| positive regulation of apoptotic process PTGS2;JAK2 GO:0034612| response to tumor necrosis factor JAK2;PTGS2 GO:0006979| response to oxidative stress JAK2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process JAK2;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway JAK2;TNFSF11 GO:0019221| cytokine-mediated signaling pathway JAK2;TNFSF11 GO:0008284| positive regulation of cell proliferation JAK2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;JAK2 GO:0042127| regulation of cell proliferation PTGS2;JAK2 39833:[DB00480 DB00756] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00756|Hexachlorophene SDHD;GLUD1;ESR1 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;SDHD;GLUD1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response ESR1;PTGS2 39834:[DB00480 DB04450] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04450|Heptyl 1-Thiohexopyranoside RHO;fpr;acpP common genes common pathways 39835:[DB00480 DB03622] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03622|2-Hydroxy-5-[4-(2-Hydroxy-Ethyl)-Piperidin-1-Yl]-5-Phenyl-1h-Pyrimidine-4,6-Dione MMP8 common genes common pathways 39836:[DB00480 DB07626] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07626|4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0010469| regulation of receptor activity PLAU;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;PLAU 39837:[DB00480 DB01689] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01689|Inhibitor Idd 384 AKR1B1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0010033| response to organic substance AKR1B1;PTGS2 39838:[DB00480 DB08257] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08257|4-{[(CYCLOHEXYLAMINO)CARBONYL]AMINO}BUTANOIC ACID EPHX2 common genes common pathways GO:0008217| regulation of blood pressure PTGS2;EPHX2 GO:0006954| inflammatory response EPHX2;PTGS2 GO:0006629| lipid metabolic process EPHX2;PTGS2 39839:[DB00480 DB06626] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes ABCB1 common pathways GO:0042493| response to drug UGT1A1;PTGS2;ABCB1;CYP1A2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP3A5;CYP2C19;PTGS2;CYP1A2;CYP3A4 GO:0099040| ABCB1 GO:0002548| monocyte chemotaxis FLT1;TNFSF11 GO:0043066| negative regulation of apoptotic process FLT4;KDR;PTGS2 GO:0008284| positive regulation of cell proliferation FLT1;FLT4;KDR;PTGS2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2;UGT1A1 GO:0046330| positive regulation of JNK cascade FLT4;TNFSF11 GO:0010033| response to organic substance CYP1A2;UGT1A1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;FLT1 GO:0055085| transmembrane transport SLCO1B1;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006810| transport ABCB1 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0006629| lipid metabolic process CYP1A2;CYP3A4;PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4 GO:0007275| multicellular organismal development FLT1;KDR;TNFSF11 GO:0001525| angiogenesis FLT1;PTGS2;FLT4;KDR GO:0014070| response to organic cyclic compound PTGS2;UGT1A1;CYP1A2 GO:0006855| drug transmembrane transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042908| xenobiotic transport ABCB1 GO:0030154| cell differentiation FLT1;KDR;TNFSF11 39840:[DB00480 DB04721] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04721|N1,N2-ETHYLENE-2-METHYLAMINO-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 GO:0008284| positive regulation of cell proliferation CSNK2A1;PTGS2 39841:[DB00480 DB07991] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07991|N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]-2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE ESR1 common genes common pathways GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 39842:[DB00480 DB05298] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05298|Tetomilast PDE4D common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity TNFSF11;PDE4D 39843:[DB00480 DB03328] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03328|dioxothiomolybdenum(VI) ion XDH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;XDH 39844:[DB00480 DB07030] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07030|(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0010033| response to organic substance AKR1B1;PTGS2 39845:[DB00480 DB05562] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05562|Naluzotan HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 39846:[DB00480 DB04339] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04339|Carbocisteine GSTP1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;GSTP1 GO:0032355| response to estradiol stimulus GSTP1;PTGS2 GO:0098869| GSTP1;PTGS2 39847:[DB00480 DB05101] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05101|Matuzumab EGFR common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGFR GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;TNFSF11 GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0098609| CDH5;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0006979| response to oxidative stress EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity EGFR;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;EGFR GO:0001503| ossification EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 GO:0014070| response to organic cyclic compound EGFR;PTGS2 39848:[DB00480 DB07242] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07242|(4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile DAPK3;PIM1 common genes common pathways GO:0043065| positive regulation of apoptotic process DAPK3;PTGS2 GO:0007275| multicellular organismal development PIM1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;PIM1 39849:[DB00480 DB06454] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD3;ABCB1;DRD2;PTGS2 GO:0007612| learning DRD3;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation DRD3;PTGS2;HTR1A GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2 39850:[DB00480 DB08389] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08389|6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE PDE10A common genes common pathways 39851:[DB00480 DB00677] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0007612| learning BCHE;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;BCHE GO:0098869| PTGS2;ALB GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;BCHE;PTGS2 39852:[DB00480 DB00136] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0007275| multicellular organismal development VDR;HOXA10;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0033280| response to vitamin D PTGS2;CYP24A1 GO:0008285| negative regulation of cell proliferation CDH5;VDR;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP24A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HOXA10;VDR GO:0009887| organ morphogenesis TNFSF11;VDR GO:0046697| decidualization VDR;PTGS2 39853:[DB00480 DB05806] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05806|Cositecan TOP1 common genes common pathways GO:0042493| response to drug TOP1;PTGS2;ABCB1 39854:[DB00480 DB04633] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04633|N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine SAT1 common genes common pathways GO:0001525| angiogenesis PTGS2;SAT1 GO:0042127| regulation of cell proliferation SAT1;PTGS2 39855:[DB00480 DB13926] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13926|Cenegermin NTRK1 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity NTRK1;TNFSF11 GO:0009314| response to radiation NTRK1;PTGS2 GO:0019233| sensory perception of pain NTRK1;PTGS2 GO:0007275| multicellular organismal development NTRK1;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;NTRK1 GO:0030154| cell differentiation NTRK1;TNFSF11 GO:0042493| response to drug ABCB1;NTRK1;PTGS2 GO:0043066| negative regulation of apoptotic process NTRK1;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic NTRK1;PTGS2 GO:0007568| aging NTRK1;PTGS2 39856:[DB00480 DB11323] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes PTGS2 common pathways GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2;PTGS1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 39857:[DB00480 DB03957] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03957|SP2456 IL2 common genes common pathways GO:0010469| regulation of receptor activity IL2;TNFSF11 GO:0007155| cell adhesion CDH5;IL2 GO:0043066| negative regulation of apoptotic process IL2;PTGS2 GO:0008284| positive regulation of cell proliferation IL2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL2 GO:0050728| negative regulation of inflammatory response CDH5;IL2 GO:0006955| immune response IL2;TNFSF11 39858:[DB00480 DB14544] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0006810| transport ABCB1;ABCG2 GO:0098609| ANXA1;CDH5 GO:0032355| response to estradiol stimulus PTGS2;ANXA1 GO:0055085| transmembrane transport ABCB1;ABCG2;SLCO1A2;SLC22A8 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation PTGS2;ANXA1 GO:0055114| oxidation-reduction process CYP3A4;HSD11B2;CYP2C8;PTGS2;CYP11B2;CYP3A5;HSD3B1;CYP3A7;CYP11B1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0002548| monocyte chemotaxis TNFSF11;ANXA1 GO:0042493| response to drug PTGS2;ABCG2;ANXA1;HSD11B2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;HSD11B2;ANXA1 GO:0008217| regulation of blood pressure PTGS2;CYP11B1 GO:0031394| positive regulation of prostaglandin biosynthetic process ANXA1;PTGS2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0014070| response to organic cyclic compound ANXA1;PTGS2 GO:0006629| lipid metabolic process CYP11B1;CYP11B2;PTGS2;CYP3A4 GO:0050727| regulation of inflammatory response PTGS2;ANXA1 GO:0043065| positive regulation of apoptotic process PTGS2;ANXA1 GO:0006955| immune response CYP11B1;TNFSF11 GO:0006954| inflammatory response ANXA1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;PTGS2 39859:[DB00480 DB14481] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0055085| transmembrane transport CACNA1I;CACNA1A;TRPV6;CACNA1E;CACNA1G;RYR1;SLC34A3;CACNA1F;ABCB1;CATSPER1;SLC20A2;CACNA1C;CACNA1D;SLC8A1;SLC34A2;RYR3;TRPV5;CALM1;SLC20A1;CACNA1H;RYR2;CACNA1S GO:0010033| response to organic substance PTGS2;CALR;CASQ1 GO:0051968| positive regulation of synaptic transmission, glutamatergic NRXN1;PTGS2 GO:0032355| response to estradiol stimulus CALR;PTGS2;SLC34A1 GO:0034605| cellular response to heat PDCD6;PTGS2 GO:0071456| cellular response to hypoxia S100B;CASR;SLC8A1;PTGS2 GO:0006810| transport ABCB1;CACNA1I;CACNA1E;CACNB4;SLC20A1;CACNB1;CACNB3;SLC20A2;SRI GO:0007568| aging PTGS2;CANX;RGN GO:0051260| protein homooligomerization TNFSF11;SLC34A1 GO:0098869| PTGS2;ALB GO:0042493| response to drug SLC8A1;PTGS2;SLC34A1;CALR;ABCB1 GO:0032496| response to lipopolysaccharide SPARC;PTGS2 GO:0007612| learning NRXN1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;SPARC;CIB1 GO:0071318| cellular response to ATP PTGS2;CIB2;RYR3 GO:0008284| positive regulation of cell proliferation CASR;CALR;S100A13;PTGS2;CIB1;S100B GO:0043066| negative regulation of apoptotic process CIB1;RGN;ALB;PTGS2;TPT1 GO:0034097| response to cytokine stimulus SPARC;PTGS2 GO:0007155| cell adhesion NRXN1;CIB1;CDH5 GO:0014070| response to organic cyclic compound PTGS2;CASR GO:0008285| negative regulation of cell proliferation CDH5;CIB1;PTGS2 GO:0051384| response to glucocorticoid stimulus SPARC;PTGS2;S100B GO:0019722| calcium-mediated signaling RYR2;TNFSF11 GO:0007613| memory PTGS2;S100B GO:0030154| cell differentiation TPT1;TNFSF11;CIB1;CALR3;CATSPER1 GO:0045907| positive regulation of vasoconstriction PTGS2;CASR GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;CIB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CIB1;TNFSF11 GO:0055074| calcium ion homeostasis CIB2;TRPV5;SLC8A1;TRPV6;CALB1;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100B;TNFSF11;S100A13;SLC20A1 GO:0001525| angiogenesis CIB1;PTGS2;PDCD6 GO:0007275| multicellular organismal development CATSPER1;RYR1;TNFSF11;RYR2 GO:0043065| positive regulation of apoptotic process S100B;PTGS2 GO:0001503| ossification TNFSF11;CASR;SLC34A1;SPARC 39860:[DB00480 DB06401] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06401|Bazedoxifene ESR1;ESR2;UGT1A8;UGT1A10 common genes common pathways GO:0006631| fatty acid metabolic process PTGS2;UGT1A8 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 39861:[DB00480 DB08102] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08102|3,5-dibromobiphenyl-4-ol TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TNFSF11;TTR 39862:[DB00480 DB07020] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07020|N-{3-[5-(1H-1,2,4-triazol-3-yl)-1H-indazol-3-yl]phenyl}furan-2-carboxamide MAPK9 common genes common pathways GO:0043065| positive regulation of apoptotic process MAPK9;PTGS2 39863:[DB00480 DB05739] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05739|CYT006-AngQb AGTR1;AGTR2 common genes common pathways GO:0050727| regulation of inflammatory response AGTR1;PTGS2 GO:0006954| inflammatory response PTGS2;AGTR2 GO:0019722| calcium-mediated signaling TNFSF11;AGTR1 GO:0008217| regulation of blood pressure AGTR2;PTGS2 GO:0008284| positive regulation of cell proliferation AGTR2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;AGTR1 GO:0010243| response to organic nitrogen AGTR2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;AGTR2 39864:[DB00480 DB09308] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09308|Solithromycin CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39865:[DB00480 DB08927] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08927|Amperozide HTR2A common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;HTR2A GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging HTR2A;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 39866:[DB00480 DB05966] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05966|TAS-108 ESR1;ESR2 common genes common pathways GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;ESR2 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 39867:[DB00480 DB04200] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04200|Matairesinol DHRS4L2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHRS4L2 39868:[DB00480 DB08263] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08263|N-(carboxycarbonyl)-D-phenylalanine HIF1AN common genes common pathways GO:0055114| oxidation-reduction process HIF1AN;PTGS2 39869:[DB00480 DB08487] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08487|3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 39870:[DB00480 DB13757] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13757|Epanolol CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 39871:[DB00480 DB07306] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07306|ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 39872:[DB00480 DB01071] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01071|Mequitazine HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory PTGS2;HRH1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2 39873:[DB00480 DB12319] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12319|Benzbromarone CYP2C9;CYP2C19;CYP2C19;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2C9 GO:0055085| transmembrane transport ABCB1;SLCO1B1;ABCB11;SLCO2B1 GO:0006810| transport ABCB11;ABCB1 GO:0006629| lipid metabolic process CYP2C9;PTGS2 39874:[DB00480 DB05488] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 39875:[DB00480 DB03428] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03428|SU9516 CDK5;CDK1;CDK2 common genes common pathways GO:0014070| response to organic cyclic compound CDK1;PTGS2 GO:0019233| sensory perception of pain PTGS2;CDK5 GO:0007275| multicellular organismal development CDK2;TNFSF11 GO:0010033| response to organic substance PTGS2;CDK2 GO:0000086| G2/M transition of mitotic cell cycle CDK2;CDK1;ABCB1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;CDK1 GO:0010243| response to organic nitrogen CDK1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CDK1 GO:0008284| positive regulation of cell proliferation PTGS2;CDK2 GO:0043066| negative regulation of apoptotic process CDK1;PTGS2 GO:0045786| negative regulation of cell cycle CDK5;PTGS2 39876:[DB00480 DB14541] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0006954| inflammatory response PTGS2;ANXA1 GO:0006955| immune response CYP11B1;TNFSF11 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ANXA1;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP11B1;PTGS2;CYP11B2 GO:0050727| regulation of inflammatory response ANXA1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;ANXA1 GO:0008217| regulation of blood pressure PTGS2;CYP11B1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0031394| positive regulation of prostaglandin biosynthetic process ANXA1;PTGS2 GO:0014070| response to organic cyclic compound ANXA1;PTGS2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0051384| response to glucocorticoid stimulus ANXA1;HSD11B2;PTGS2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0002548| monocyte chemotaxis TNFSF11;ANXA1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process HSD11B2;CYP3A4;CYP3A7;CYP11B1;CYP3A5;HSD3B1;PTGS2;CYP11B2;CYP2C8 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCG2;PTGS2;ANXA1;HSD11B2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;ANXA1 GO:0042127| regulation of cell proliferation ANXA1;PTGS2 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCG2;SLCO1A2;SLC22A8;ABCB1 GO:0006810| transport ABCG2;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;ANXA1 GO:0098609| CDH5;ANXA1 39877:[DB00480 DB05032] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05032|REV131 HRH4 common genes common pathways GO:0006954| inflammatory response HRH4;PTGS2 39878:[DB00480 DB03577] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03577|Alpha-Benzyl-Aminobenzyl-Phosphonic Acid ACPP common genes common pathways 39879:[DB00480 DB06525] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06525|Ganstigmine ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 39880:[DB00480 DB00173] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00173|Adenine APRT;ACACB;ACP1;PECR;SRPK2;ruvB;MTAP;cobT;UGT1A1 common genes common pathways GO:0006629| lipid metabolic process ACACB;PTGS2;PECR GO:0001525| angiogenesis SRPK2;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;ACACB;PECR GO:0030154| cell differentiation TNFSF11;SRPK2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0014070| response to organic cyclic compound PTGS2;ACACB;UGT1A1 GO:0008284| positive regulation of cell proliferation SRPK2;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0055114| oxidation-reduction process PECR;PTGS2 GO:0042493| response to drug ACACB;PTGS2;UGT1A1;ABCB1 GO:0006631| fatty acid metabolic process PECR;PTGS2;ACACB GO:0010033| response to organic substance UGT1A1;PTGS2 39881:[DB00480 DB00927] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;PTGS2 GO:0055085| transmembrane transport SLC22A8;SLC22A2;ABCB1 GO:0006955| immune response TNFSF11;HRH2 GO:0006855| drug transmembrane transport SLC22A2;ABCB1 GO:0045907| positive regulation of vasoconstriction HRH2;PTGS2 GO:0007613| memory HRH2;PTGS2 39882:[DB00480 DB09006] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0046697| decidualization PPARD;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;PPARD GO:0010033| response to organic substance PTGS2;PPARG;PPARD GO:0042127| regulation of cell proliferation PPARD;PTGS2 GO:0043066| negative regulation of apoptotic process PPARD;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA;PPARG GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0050728| negative regulation of inflammatory response CDH5;PPARD;PPARA GO:0007566| embryo implantation PPARD;PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PPARD;PPARA;PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG 39883:[DB00480 DB00979] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00979|Cyclopentolate CHRM1;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0007612| learning BCHE;PTGS2 GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;BCHE 39884:[DB00480 DB07577] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07577|6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE TYMS common genes common pathways GO:0034097| response to cytokine stimulus PTGS2;TYMS GO:0042493| response to drug PTGS2;TYMS;ABCB1 GO:0007568| aging PTGS2;TYMS GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;TYMS 39885:[DB00480 DB08604] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08604|Triclosan fabI;fabI;fabI;fabI;NR1I2;AR;NR1I3;PPARG;TPO common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0008285| negative regulation of cell proliferation CDH5;PPARG;AR;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0098869| PTGS2;TPO GO:0006979| response to oxidative stress PTGS2;TPO GO:0006810| transport AR;ABCB1 GO:0010033| response to organic substance PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;AR;PPARG;TNFSF11;NR1I2 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0055114| oxidation-reduction process PTGS2;TPO 39886:[DB00480 DB07489] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07489|4-Amino-2-[(3-chlorophenyl)amino]-5-(4-fluorobenzoyl)-1,3-thiazol-3-ium CSNK1G3 common genes common pathways 39887:[DB00480 DB02811] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02811|Diethylphosphono Group BCHE;fbpC;BCHE common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0007612| learning BCHE;PTGS2 39888:[DB00480 DB04847] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04847|Roxadustat EGLN1;EGLN2;EGLN3 common genes common pathways GO:0055114| oxidation-reduction process EGLN1;PTGS2;EGLN3;EGLN2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGLN1;TNFSF11 GO:0042127| regulation of cell proliferation EGLN3;PTGS2 39889:[DB00480 DB08734] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08734|6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE TYMS common genes common pathways GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0042493| response to drug ABCB1;TYMS;PTGS2 GO:0034097| response to cytokine stimulus TYMS;PTGS2 GO:0007568| aging TYMS;PTGS2 39890:[DB00480 DB09116] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09116|Calcium carbimide ALDH3B2;CAT common genes common pathways GO:0070542| response to fatty acid PTGS2;CAT GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNFSF11 GO:0009314| response to radiation CAT;PTGS2 GO:0006629| lipid metabolic process ALDH3B2;PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2 GO:0007568| aging PTGS2;CAT GO:0006979| response to oxidative stress CAT;PTGS2 GO:0098869| PTGS2;CAT GO:0042493| response to drug PTGS2;ABCB1;CAT GO:0055114| oxidation-reduction process CAT;ALDH3B2;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;CAT 39891:[DB00480 DB09347] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09347|Acetrizoic acid ALB common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| PTGS2;ALB 39892:[DB00480 DB09109] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09109|Turoctocog alfa F9;F10;F2 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;F2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 GO:0010469| regulation of receptor activity F2;TNFSF11 GO:0007275| multicellular organismal development F2;TNFSF11 39893:[DB00480 DB05029] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05029|Lancovutide PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PLA2G4A 39894:[DB00480 DB13520] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13520|Metergoline SCN2A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN2A 39895:[DB00480 DB08369] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08369|1-(biphenyl-4-ylmethyl)-1H-imidazole CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;PTGS2 39896:[DB00480 DB08348] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08348|N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE EEF2;PARP3;PARP15 common genes common pathways GO:0042493| response to drug PTGS2;EEF2;ABCB1 GO:0007568| aging PTGS2;EEF2 GO:0032355| response to estradiol stimulus EEF2;PTGS2 39897:[DB00480 DB07219] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07219|BENZYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 39898:[DB00480 DB05876] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05876|PDE4 PDE4A common genes common pathways 39899:[DB00480 DB02431] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02431|Cytidine-5'-Triphosphate rfbF;UCK2;coaBC common genes common pathways 39900:[DB00480 DB14019] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14019|Fosnetupitant CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 39901:[DB00480 DB09059] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0014070| response to organic cyclic compound OXTR;PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;AVPR1A GO:0045907| positive regulation of vasoconstriction PTGS2;AVPR1B;AVPR2;AVPR1A;OXTR GO:0019722| calcium-mediated signaling TNFSF11;AVPR1A GO:0007613| memory OXTR;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;OXTR GO:0010033| response to organic substance AVPR1A;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic OXTR;PTGS2 GO:0032355| response to estradiol stimulus OXTR;PTGS2 GO:0042493| response to drug OXTR;ABCB1;PTGS2 GO:0008284| positive regulation of cell proliferation AVPR2;AVPR1A;PTGS2 GO:0034097| response to cytokine stimulus AVPR2;OXTR;PTGS2 39902:[DB00480 DB07902] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07902|TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE METAP1 common genes common pathways 39903:[DB00480 DB08805] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08805|Metiamide HRH2 common genes common pathways GO:0045907| positive regulation of vasoconstriction HRH2;PTGS2 GO:0007613| memory PTGS2;HRH2 GO:0006955| immune response HRH2;TNFSF11 39904:[DB00480 DB01454] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0007613| memory SLC6A4;HTR2A;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2B;HTR2A GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0042493| response to drug ABCB1;SLC6A4;HTR2C;HTR2B;SLC6A2;PTGS2;SLC6A3;HTR2A GO:0007568| aging PTGS2;HTR2A;SLC6A3 GO:0006810| transport SLC6A2;ABCB1 GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0055085| transmembrane transport SLC6A2;SLC18A2;SLC6A3;ABCB1;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;TNFSF11 39905:[DB00480 DB00204] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0007613| memory PTGS2;KCNK2 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0010942| positive regulation of cell death PTGS2;KCNK2 GO:0071456| cellular response to hypoxia PTGS2;KCNK2 GO:0055085| transmembrane transport SLC22A2;KCNH2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 39906:[DB00480 DB08072] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08072|4-(2-AMINOETHOXY)-3,5-DICHLORO-N-[3-(1-METHYLETHOXY)PHENYL]BENZAMIDE PLAU common genes common pathways GO:0010469| regulation of receptor activity PLAU;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;PLAU 39907:[DB00480 DB00914] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0071456| cellular response to hypoxia PRKAA1;PTGS2 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0055085| transmembrane transport SLC22A2;ABCB1;SLC22A1 GO:0032496| response to lipopolysaccharide PTGS2;KCNJ8 GO:0008284| positive regulation of cell proliferation PTGS2;PRKAA1 GO:0043066| negative regulation of apoptotic process PTGS2;PRKAA1 GO:0006631| fatty acid metabolic process PTGS2;PRKAA1 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006633| fatty acid biosynthetic process PRKAA1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;SLC22A1;SLC22A2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;PRKAA1 39908:[DB00480 DB07221] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07221|(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM GGPS1 common genes common pathways 39909:[DB00480 DB01956] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01956|Taurine GLRA1;GRIN2B;GLRA2;GLRA3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABBR1;TGM6;BAAT;SLC36A1;SLC6A6;SLC15A1 common genes common pathways GO:0006631| fatty acid metabolic process PTGS2;BAAT GO:0042493| response to drug GABRG3;ABCB1;PTGS2 GO:0006810| transport GABRD;GABRB1;SLC6A6;GABRA6;GABRA4;GABRA3;GABRA5;GABRB2;ABCB1;GABRG2;GRIN2B;SLC15A1;GABRB3;GABRA1 GO:0051260| protein homooligomerization TNFSF11;GLRA1;GLRA3 GO:0055085| transmembrane transport SLC36A1;SLC15A1;ABCB1 GO:0006629| lipid metabolic process BAAT;PTGS2 GO:0019722| calcium-mediated signaling GRIN2B;TNFSF11 39910:[DB00480 DB02889] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02889|4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose AMY2A;AMY2A common genes common pathways 39911:[DB00480 DB01780] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01780|Fusicoccin YWHAE common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;YWHAE GO:0034605| cellular response to heat YWHAE;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;YWHAE 39912:[DB00480 DB04465] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04465|Lactose GLT6D1;GLTP;LGALS3 common genes common pathways GO:0002548| monocyte chemotaxis LGALS3;TNFSF11 GO:0030154| cell differentiation LGALS3;TNFSF11 39913:[DB00480 DB01717] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01717|Bis(Adenosine)-5'-Pentaphosphate adk;adk;adk;AK2;AK8;adk;AK1 common genes common pathways 39914:[DB00480 DB07181] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07181|4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion DPP4;CDH5 39915:[DB00480 DB12887] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12887|Tazemetostat EZH2 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;EZH2 GO:0032355| response to estradiol stimulus EZH2;PTGS2 GO:0042127| regulation of cell proliferation EZH2;PTGS2 39916:[DB00480 DB11831] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11831|Dinitrochlorobenzene MGMT;GSTP1 common genes common pathways GO:0014070| response to organic cyclic compound MGMT;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;GSTP1 GO:0098869| PTGS2;GSTP1 GO:0042493| response to drug ABCB1;MGMT;PTGS2 GO:0043066| negative regulation of apoptotic process MGMT;GSTP1;PTGS2 39917:[DB00480 DB02628] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02628|1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;XIAP GO:0042127| regulation of cell proliferation PTGS2;XIAP GO:0016567| protein ubiquitination CRBN;XIAP GO:0050727| regulation of inflammatory response XIAP;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process XIAP;PTGS2 39918:[DB00480 DB05744] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05744|CRx-139 TNF;IL6;CRP;IL10 common genes common pathways GO:0006955| immune response TNF;IL10;IL6;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;IL10;IL6;TNFSF11 GO:0006954| inflammatory response IL6;PTGS2;TNF;CRP;IL10 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IL6;TNF GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0043065| positive regulation of apoptotic process TNF;PTGS2;IL6 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0008285| negative regulation of cell proliferation PTGS2;IL10;IL6;CDH5 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2;IL10;IL6 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF;IL6 GO:0042493| response to drug ABCB1;IL10;PTGS2 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0002548| monocyte chemotaxis TNFSF11;IL6 GO:0048661| positive regulation of smooth muscle cell proliferation IL6;TNF;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;IL10 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;TNF GO:0019221| cytokine-mediated signaling pathway IL6;TNFSF11 GO:0032496| response to lipopolysaccharide IL10;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0043066| negative regulation of apoptotic process IL6;PTGS2;IL10 GO:0008284| positive regulation of cell proliferation PTGS2;IL6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL10;TNF;TNFSF11;IL6 GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0010033| response to organic substance IL10;TNF;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;IL6;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0007568| aging IL10;PTGS2 GO:0097756| CRP;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF 39919:[DB00480 DB08078] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08078|{4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid PPARD common genes common pathways GO:0010033| response to organic substance PTGS2;PPARD GO:0071456| cellular response to hypoxia PTGS2;PPARD GO:0046697| decidualization PTGS2;PPARD GO:0050728| negative regulation of inflammatory response CDH5;PPARD GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0043066| negative regulation of apoptotic process PPARD;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PPARD GO:0007566| embryo implantation PPARD;PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0006629| lipid metabolic process PPARD;PTGS2 39920:[DB00480 DB05867] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05867|99mTc-14 F7 Mab ST3GAL5 common genes common pathways 39921:[DB00480 DB12228] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12228|Telcagepant CALCA;CALCB;CALCRL common genes common pathways GO:0001525| angiogenesis PTGS2;CALCRL GO:0008217| regulation of blood pressure CALCA;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CALCRL GO:0050728| negative regulation of inflammatory response CDH5;CALCRL GO:0045986| negative regulation of smooth muscle contraction PTGS2;CALCRL GO:0048661| positive regulation of smooth muscle cell proliferation CALCRL;PTGS2 GO:0010469| regulation of receptor activity CALCA;CALCB;TNFSF11 39922:[DB00480 DB00489] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0055085| transmembrane transport ABCB1;KCNH2 GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 39923:[DB00480 DB05003] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05003|Imexon RRM2;RRM1 common genes common pathways GO:0055114| oxidation-reduction process RRM1;RRM2;PTGS2 39924:[DB00480 DB03667] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03667|Acetic Acid Salicyloyl-Amino-Ester PTGS1 common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS2;PTGS1 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;PTGS1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 39925:[DB00480 DB02562] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02562|Quinonoid 7,8-Tetrahydrobiopterin PAH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;PAH 39926:[DB00480 DB00248] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes ABCB1 common pathways GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A;HTR2B;HTR2A;ADRA1D;DRD3;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11;ADRB2 GO:1901529| ABCB1 GO:0007612| learning DRD5;DRD3;DRD1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug HTR1B;ABCB1;DRD3;HTR2C;HTR2B;PTGS2;DRD2;ADRA1A;DRD1;HTR2A GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0099040| ABCB1 GO:0006810| transport ABCB1 GO:0007568| aging PTGS2;HTR2A;ADRA1A GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11;HTR2B;HTR2A GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0007275| multicellular organismal development TNFSF11;ADRA1D;ADRA1B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA2C;ADRA1D;ADRA1A;HTR2A;PTGS2;ADRA1B GO:0045453| bone resorption ADRB2;TNFSF11 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0007613| memory PTGS2;DRD1;HTR2A GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1A;PTGS2;ADRA1B GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;DRD2;PTGS2 GO:0006855| drug transmembrane transport ABCB1 39927:[DB00480 DB00209] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0006629| lipid metabolic process PTGS2;CYP2D6 39928:[DB00480 DB01963] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01963|Phenylethane Boronic Acid CTRB1 common genes common pathways 39929:[DB00480 DB03359] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03359|M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 39930:[DB00480 DB04978] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04978|SP1049C TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A 39931:[DB00480 DB04419] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04419|D-norleucine PTH;HNF1A;PAH common genes common pathways GO:0033280| response to vitamin D PTH;PTGS2 GO:0045453| bone resorption PTH;TNFSF11 GO:0010469| regulation of receptor activity PTH;TNFSF11 GO:0042493| response to drug ABCB1;PTH;PTGS2 GO:0055114| oxidation-reduction process PTGS2;PAH GO:0045944| positive regulation of transcription from RNA polymerase II promoter PTH;TNFSF11;HNF1A 39932:[DB00480 DB05205] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05205|CX157 MAOA common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOA 39933:[DB00480 DB04090] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04090|RH-1 NQO1 common genes common pathways GO:0006979| response to oxidative stress PTGS2;NQO1 GO:0032355| response to estradiol stimulus NQO1;PTGS2 GO:0007568| aging PTGS2;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;NQO1 GO:0014070| response to organic cyclic compound NQO1;PTGS2 39934:[DB00480 DB08293] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08293|(5E)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HSP90AB1 GO:0010033| response to organic substance HSP90AB1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HSP90AB1 GO:0042493| response to drug PTGS2;ABCB1;HSP90AB1 39935:[DB00480 DB00673] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00673|Aprepitant TACR1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;TACR1 GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;CYP3A5;CYP3A7;CYP2C19;PTGS2 GO:0045907| positive regulation of vasoconstriction TACR1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction TACR1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;TACR1 GO:0014070| response to organic cyclic compound TACR1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9 GO:0019233| sensory perception of pain PTGS2;TACR1 GO:0006954| inflammatory response TACR1;PTGS2 39936:[DB00480 DB02132] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02132|Zenarestat AKR1B1 common genes common pathways GO:0010033| response to organic substance PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 39937:[DB00480 DB04426] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04426|Alpha-Methyl-N-Acetyl-D-Glucosamine MBL2 common genes common pathways GO:0006979| response to oxidative stress PTGS2;MBL2 39938:[DB00480 DB07251] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07251|N'-(3-CHLORO-4-METHOXY-PHENYL)-N-(3,4,5-TRIMETHOXYPHENYL)-1,3,5-TRIAZINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0007155| cell adhesion CDH5;EPHB4 GO:0001525| angiogenesis EPHB4;PTGS2 GO:0007275| multicellular organismal development EPHB4;TNFSF11 39939:[DB00480 DB01028] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;MT-ND1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ATP2C1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C9;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006810| transport GABRB3;GABRA1;ABCB1;GABRG2;GABRA5;GABRA3;GABRB2;GABRD;GABRB1;GABRA4;GABRA6 GO:0051260| protein homooligomerization GLRA1;KCNA1;TNFSF11 GO:0055085| transmembrane transport KCNA1;ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;MT-ND1;ABCB1;GABRG3;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2E1;MT-ND1;CYP3A4;CYP2A6;CYP2C9;CYP2B6;CYP2D6;CYP1A2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 39940:[DB00480 DB04983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04983|Denufosol P2RY2 common genes common pathways 39941:[DB00480 DB06137] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06137|KX-01 SRC common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:1902533| TNFSF11;SRC GO:0071456| cellular response to hypoxia PTGS2;SRC GO:0098609| SRC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade SRC;TNFSF11 GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug PTGS2;SRC;ABCB1 GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 39942:[DB00480 DB04271] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04271|3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester PDE4D common genes common pathways GO:0007568| aging PDE4D;PTGS2 GO:0010469| regulation of receptor activity PDE4D;TNFSF11 39943:[DB00480 DB11714] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11714|Durvalumab CD274;CD80 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;CD80 GO:0034097| response to cytokine stimulus CD274;PTGS2 GO:0006955| immune response TNFSF11;CD274 39944:[DB00480 DB03753] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03753|Flurbiprofen Methyl Ester PTGS1 common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS2;PTGS1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 39945:[DB00480 DB14025] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;CYP2C9;CYP2D6;PTGS2;CYP2C19 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;CYP2C9;CYP2D6;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 39946:[DB00480 DB14634] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14634|Fluprednidene acetate CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 39947:[DB00480 DB08455] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08455|Ro 12-7310 CRABP2 common genes common pathways 39948:[DB00480 DB04690] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04690|Camptothecin TOP1;ALB;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0098869| ALB;PTGS2 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:1901529| ABCB1 GO:0042493| response to drug ABCB1;TOP1;PTGS2;ABCG2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 39949:[DB00480 DB03499] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03499|Malate Ion fumC;glcB;ME2;CS common genes common pathways GO:0055114| oxidation-reduction process ME2;PTGS2 39950:[DB00480 DB02486] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02486|2-Hydroxyethyl Disulfide GSTA1;GSTA1 common genes common pathways GO:0098869| GSTA1;PTGS2 39951:[DB00480 DB06994] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06994|(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion DPP4;CDH5 39952:[DB00480 DB07604] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07604|(6AR,11AS,11BR)-10-ACETYL-9-HYDROXY-7,7-DIMETHYL-2,6,6A,7,11A,11B-HEXAHYDRO-11H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-11-ONE ATP2A1 common genes common pathways 39953:[DB00480 DB00154] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes PTGS2 common pathways GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0042493| response to drug PTGS2;ABCB1 GO:0009750| response to fructose stimulus PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0007612| learning PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0007568| aging PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:1902219| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0019233| sensory perception of pain PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0030728| ovulation PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0008285| negative regulation of cell proliferation FABP7;PTGS2;CDH5 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 39954:[DB00480 DB00221] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00221|Isoetarine ADRB1;ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0050873| brown fat cell differentiation ADRB2;ADRB1;PTGS2 GO:0045453| bone resorption ADRB2;TNFSF11 39955:[DB00480 DB05227] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05227|APD791 HTR2A common genes common pathways GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A GO:0042493| response to drug HTR2A;PTGS2;ABCB1 GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0007568| aging HTR2A;PTGS2 39956:[DB00480 DB03487] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03487|3-Aminosuccinimide LYZ common genes common pathways GO:0006954| inflammatory response PTGS2;LYZ 39957:[DB00480 DB05104] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05104|Asimadoline OPRK1 common genes common pathways GO:0009314| response to radiation OPRK1;PTGS2 GO:0019233| sensory perception of pain PTGS2;OPRK1 GO:0006955| immune response TNFSF11;OPRK1 39958:[DB00480 DB04297] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04297|7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide HDAC8;HDAC7 common genes common pathways GO:0007043| cell-cell junction assembly CDH5;HDAC7 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;HDAC7 39959:[DB00480 DB05013] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05013|Ingenol Mebutate PRKCD;PRKCA common genes common pathways GO:0045780| positive regulation of bone resorption PRKCA;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;PRKCD GO:0007155| cell adhesion PRKCA;CDH5 GO:0050728| negative regulation of inflammatory response CDH5;PRKCD GO:0001525| angiogenesis PRKCA;PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2;PRKCD 39960:[DB00480 DB04803] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04803|Verdoheme HMOX1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HMOX1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMOX1 GO:0034605| cellular response to heat HMOX1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;HMOX1 GO:0051260| protein homooligomerization TNFSF11;HMOX1 GO:0006979| response to oxidative stress PTGS2;HMOX1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HMOX1 GO:0001525| angiogenesis PTGS2;HMOX1 GO:0043065| positive regulation of apoptotic process PTGS2;HMOX1 GO:0008217| regulation of blood pressure PTGS2;HMOX1 GO:0008285| negative regulation of cell proliferation CDH5;HMOX1;PTGS2 39961:[DB00480 DB05706] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A 39962:[DB00480 DB04487] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04487|N-Methylleucine CXCL10 common genes common pathways GO:0006954| inflammatory response PTGS2;CXCL10 GO:0006955| immune response TNFSF11;CXCL10 GO:0033280| response to vitamin D CXCL10;PTGS2 GO:0042127| regulation of cell proliferation CXCL10;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CXCL10 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CXCL10;TNFSF11 GO:0008284| positive regulation of cell proliferation CXCL10;PTGS2 GO:0010469| regulation of receptor activity CXCL10;TNFSF11 GO:0034605| cellular response to heat CXCL10;PTGS2 39963:[DB00480 DB08167] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08167|Methylthioninium ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 39964:[DB00480 DB11584] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11584|Pipradrol DRD1;DRD5 common genes common pathways GO:0007613| memory PTGS2;DRD1 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0007612| learning PTGS2;DRD1;DRD5 GO:0042493| response to drug ABCB1;PTGS2;DRD1 39965:[DB00480 DB08658] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08658|ETHYL HYDROGEN DIETHYLAMIDOPHOSPHATE BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug ABCB1;BCHE;PTGS2 39966:[DB00480 DB05492] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05492|Epicept NP-1 OPRM1;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;OPRL1 common genes common pathways GO:0042493| response to drug ADRA1A;HTR2A;HTR2B;PTGS2;HTR2C;ABCB1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;PTGS2;HTR2B;HTR2A GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2A;HTR2B GO:0032355| response to estradiol stimulus OPRL1;PTGS2 GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0019233| sensory perception of pain PTGS2;HTR2A;OPRM1;OPRL1 GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0009314| response to radiation PTGS2;OPRM1 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2;ADRA1A GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0007613| memory HRH1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction ADRA1A;HTR2A;ADRA1B;PTGS2;HRH1;ADRA2C;ADRA1D 39967:[DB00480 DB02498] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02498|Carba-Nicotinamide-Adenine-Dinucleotide PARP1 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;TNFSF11 39968:[DB00480 DB02123] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCB11;ABCB1;SLC10A2;SLC10A1 GO:0006810| transport ABCB11;SLC10A2;SLC10A1;ABCB1 39969:[DB00480 DB05890] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05890|VEGF-AS VEGFA common genes common pathways GO:0030154| cell differentiation TNFSF11;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2 GO:0001525| angiogenesis PTGS2;VEGFA GO:0007275| multicellular organismal development TNFSF11;VEGFA GO:0042327| positive regulation of phosphorylation VEGFA;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0010469| regulation of receptor activity TNFSF11;VEGFA GO:0043406| positive regulation of MAP kinase activity TNFSF11;VEGFA GO:0060749| mammary gland alveolus development TNFSF11;VEGFA GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VEGFA GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;VEGFA 39970:[DB00480 DB07779] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07779|N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 39971:[DB00480 DB12328] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12328|Cantharidin AHR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AHR 39972:[DB00480 DB08043] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08043|1-[4-(PYRIDIN-4-YLOXY)PHENYL]-3-[3-(TRIFLUOROMETHYL)PHENYL]UREA ABL1 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;ABL1 GO:0007155| cell adhesion ABL1;CDH5 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNFSF11 GO:0043065| positive regulation of apoptotic process ABL1;PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 39973:[DB00480 DB00817] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00817|Rosoxacin gyrB;parC;CYP1A2 common genes common pathways GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 39974:[DB00480 DB07623] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07623|4,4'-DIPYRIDYL DISULFIDE CYP2A6 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2A6 39975:[DB00480 DB07524] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07524|N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PIM1 GO:0007275| multicellular organismal development TNFSF11;PIM1 39976:[DB00480 DB07248] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07248|7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE PTK2 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PTK2 GO:0008284| positive regulation of cell proliferation PTGS2;PTK2 GO:0042127| regulation of cell proliferation PTK2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PTK2 GO:0007179| transforming growth factor beta receptor signaling pathway PTK2;CDH5 GO:0007275| multicellular organismal development TNFSF11;PTK2 GO:0001525| angiogenesis PTK2;PTGS2 39977:[DB00480 DB02778] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02778|2,5-Anhydroglucitol-1,6-Biphosphate FBP1 common genes common pathways 39978:[DB00480 DB03951] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03951|N-acetyl-D-glucosamine-6-phosphate GNPDA1 common genes common pathways 39979:[DB00480 DB05319] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05319|Oportuzumab monatox EPCAM common genes common pathways GO:0098609| EPCAM;CDH5 GO:0008284| positive regulation of cell proliferation EPCAM;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EPCAM 39980:[DB00480 DB07254] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07254|N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL]AMINO]PHENYL]METHANESULFONAMIDE EPHB4 common genes common pathways GO:0001525| angiogenesis PTGS2;EPHB4 GO:0007275| multicellular organismal development TNFSF11;EPHB4 GO:0007155| cell adhesion EPHB4;CDH5 39981:[DB00480 DB09076] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:1901529| ABCB1 GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 39982:[DB00480 DB08804] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08804|Nandrolone decanoate AR;CYP19A1;MAOB;MAOA common genes common pathways GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0055114| oxidation-reduction process CYP19A1;MAOA;PTGS2;MAOB GO:0042493| response to drug ABCB1;MAOB;PTGS2 GO:0006810| transport ABCB1;AR 39983:[DB00480 DB08516] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08516|(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE] MAOB common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOB GO:0042493| response to drug ABCB1;PTGS2;MAOB GO:0032496| response to lipopolysaccharide MAOB;PTGS2 39984:[DB00480 DB01342] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01342|Forasartan AGTR1 common genes common pathways GO:0042127| regulation of cell proliferation AGTR1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0019722| calcium-mediated signaling TNFSF11;AGTR1 39985:[DB00480 DB05049] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05049|DDP733 HTR3A common genes common pathways 39986:[DB00480 DB03553] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03553|Glutaric Acid ilvE;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0055085| transmembrane transport SLC22A11;SLC22A6;SLC22A8;SLC22A7;ABCB1 39987:[DB00480 DB00246] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0007612| learning DRD1;PTGS2;DRD5;DRD3 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation CHRM1;DRD3;ADRA2A;PTGS2;HTR1A;HTR2A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug HTR2A;DRD1;DRD2;ADRA1A;PTGS2;CYP1A2;HTR2C;DRD3;ABCB1;HTR1B GO:0055114| oxidation-reduction process CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0007568| aging PTGS2;ADRA1A;HTR2A GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11;HTR2A GO:0007275| multicellular organismal development ADRA1B;TNFSF11 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 GO:0007613| memory HRH1;DRD1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;ADRA2C;HTR2A;ADRA1A;PTGS2;ADRA1B GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0045987| positive regulation of smooth muscle contraction CHRM3;ADRA1A;ADRA1B;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;ADRA1A 39988:[DB00480 DB07900] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07900|3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE MMP8 common genes common pathways 39989:[DB00480 DB00907] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0032355| response to estradiol stimulus SLC6A4;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0007568| aging SLC6A3;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0055085| transmembrane transport SLC6A3;SLC22A2;SLC6A2;SCN10A;SCN5A;ABCB1;SLC6A4;SCN11A GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0007612| learning PTGS2;BCHE GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0042493| response to drug BCHE;ABCB1;SLC6A4;SCN11A;SLC6A3;SLC6A2;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C8;PTGS2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0007613| memory SLC6A4;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0019233| sensory perception of pain PTGS2;SCN10A GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 39990:[DB00480 DB03796] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03796|Palmitic Acid PAEP;HNF4G;CYP2C8;TRAPPC3;RHO;SEC14L2;PPT1;PMP2;LALBA;PPARA;FABP4;FABP5;FABP3;FABP2;ALB common genes common pathways GO:0070542| response to fatty acid FABP3;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;FABP3;CDH5 GO:0007275| multicellular organismal development PAEP;TNFSF11 GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0006629| lipid metabolic process PTGS2;FABP5;PPARA GO:0098869| PTGS2;ALB GO:0043066| negative regulation of apoptotic process ALB;PTGS2;PPT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA;HNF4G GO:0006631| fatty acid metabolic process PTGS2;PPARA;FABP3 GO:0042493| response to drug PTGS2;ABCB1;FABP3 GO:0055114| oxidation-reduction process PTGS2;CYP2C8 GO:0050728| negative regulation of inflammatory response PPARA;CDH5 39991:[DB00480 DB07847] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07847|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 39992:[DB00480 DB05187] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0050728| negative regulation of inflammatory response PPARA;PPARD;CDH5 GO:0042127| regulation of cell proliferation PTGS2;PPARD GO:0043066| negative regulation of apoptotic process PTGS2;PPARD GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG;PPARA GO:0010033| response to organic substance PTGS2;PPARG;PPARD GO:0046697| decidualization PTGS2;PPARD GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;PPARA;PPARD;PTGS2 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0007566| embryo implantation PPARD;PTGS2 GO:0030154| cell differentiation PPARD;TNFSF11 39993:[DB00480 DB05838] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05838|OPC-51803 AVPR2 common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;AVPR2 GO:0008284| positive regulation of cell proliferation AVPR2;PTGS2 GO:0034097| response to cytokine stimulus AVPR2;PTGS2 39994:[DB00480 DB03107] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03107|Beta-Alanine panC;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 39995:[DB00480 DB07026] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07026|(1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 39996:[DB00480 DB01355] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0019233| sensory perception of pain PTGS2;CHRNA4 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1;CYP3A4;CYP2C9 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0007613| memory PTGS2;CHRNA7 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C9;PTGS2;CYP2C19;CYP2E1;PTGS1 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0006810| transport GRIK2;GABRA6;GABRA4;GABRA5;GABRA3;ABCB1;GABRA1 GO:0006979| response to oxidative stress PTGS1;PTGS2;CHRNA4 GO:0098869| PTGS2;PTGS1 GO:0055085| transmembrane transport ABCB1;GRIK2 39997:[DB00480 DB03729] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03729|2-Amino-5-Hydroxy-Benzimidazole PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLAU GO:0010469| regulation of receptor activity TNFSF11;PLAU 39998:[DB00480 DB07270] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07270|N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE FBP1 common genes common pathways 39999:[DB00480 DB04454] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04454|Alpha-Aminobutyric Acid EGF;GATM common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGF GO:0051897| positive regulation of protein kinase B signaling cascade EGF;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;EGF GO:0060749| mammary gland alveolus development TNFSF11;EGF GO:0070371| ERK1 and ERK2 cascade TNFSF11;EGF GO:0042327| positive regulation of phosphorylation EGF;TNFSF11 GO:0007275| multicellular organismal development TNFSF11;GATM GO:0001525| angiogenesis PTGS2;EGF 40000:[DB00480 DB00754] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00754|Ethotoin SCN5A;NR1I2 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TNFSF11 GO:0055085| transmembrane transport ABCB1;SCN5A 40001:[DB00480 DB02705] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02705|6-[N-(1-Isopropyl-1,2,3,4-Tetrahydro-7-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PLAU GO:0042127| regulation of cell proliferation PLAU;PTGS2 40002:[DB00480 DB04775] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04775|Reidispongiolide C ACTA1 common genes common pathways GO:0010226| response to lithium ion PTGS2;ACTA1 40003:[DB00480 DB06080] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06080|ABT-869 FLT3;FLT1;KDR;FLT4;KIT;CSF1R common genes common pathways GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;FLT4 GO:0001525| angiogenesis PTGS2;KDR;FLT4;FLT1 GO:0007275| multicellular organismal development FLT1;KDR;CSF1R;TNFSF11 GO:0009314| response to radiation KIT;PTGS2 GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0006954| inflammatory response CSF1R;KIT;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;KIT GO:0030154| cell differentiation FLT1;KDR;TNFSF11;FLT3 GO:0008285| negative regulation of cell proliferation CSF1R;PTGS2;CDH5 GO:0042127| regulation of cell proliferation KIT;PTGS2 GO:0046330| positive regulation of JNK cascade FLT4;TNFSF11 GO:0008284| positive regulation of cell proliferation FLT1;KDR;FLT4;CSF1R;KIT;PTGS2;FLT3 GO:0043066| negative regulation of apoptotic process CSF1R;PTGS2;KDR;FLT4 GO:0002548| monocyte chemotaxis TNFSF11;FLT1 GO:0030316| osteoclast differentiation TNFSF11;CSF1R GO:0010243| response to organic nitrogen PTGS2;FLT3 GO:0019221| cytokine-mediated signaling pathway TNFSF11;FLT3;CSF1R;KIT GO:0051897| positive regulation of protein kinase B signaling cascade KIT;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;FLT3;KIT;FLT1 40004:[DB00480 DB06642] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06642|Bevasiranib VEGFA common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;VEGFA GO:0071456| cellular response to hypoxia PTGS2;VEGFA GO:0010469| regulation of receptor activity TNFSF11;VEGFA GO:0060749| mammary gland alveolus development VEGFA;TNFSF11 GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;VEGFA GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;VEGFA GO:0030154| cell differentiation VEGFA;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0042327| positive regulation of phosphorylation VEGFA;TNFSF11 GO:0001525| angiogenesis PTGS2;VEGFA GO:0007275| multicellular organismal development VEGFA;TNFSF11 40005:[DB00480 DB11182] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process LTF;PTGS2;ALB GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LTF;TNFSF11 GO:0001503| ossification LTF;TNFSF11 GO:0006954| inflammatory response LYZ;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;LTF 40006:[DB00480 DB08708] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08708|N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;PTGS2 GO:0007275| multicellular organismal development PIM1;TNFSF11 40007:[DB00480 DB07482] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07482|(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 40008:[DB00480 DB03940] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03940|Oxamic Acid LDHA;LDHB;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A3;ABCB1 GO:0042493| response to drug ABCB1;LDHA;PTGS2 GO:0055114| oxidation-reduction process PTGS2;LDHB;LDHA GO:0014070| response to organic cyclic compound PTGS2;LDHA GO:0043065| positive regulation of apoptotic process LDHA;PTGS2 40009:[DB00480 DB04770] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04770|O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL PDXK common genes common pathways 40010:[DB00480 DB06709] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06709|Methacholine CHRM3 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 40011:[DB00480 DB04014] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04014|Alsterpaullone CDK5;CDK1;GSK3B common genes common pathways GO:0030154| cell differentiation TNFSF11;GSK3B GO:0014070| response to organic cyclic compound PTGS2;CDK1 GO:0007275| multicellular organismal development TNFSF11;GSK3B GO:0019233| sensory perception of pain CDK5;PTGS2 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;GSK3B;CDK1 GO:0000086| G2/M transition of mitotic cell cycle CDK1;ABCB1 GO:0043066| negative regulation of apoptotic process CDK1;GSK3B;PTGS2 GO:0045786| negative regulation of cell cycle CDK5;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CDK1 GO:0042493| response to drug CDK1;ABCB1;PTGS2 40012:[DB00480 DB02532] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02532|2,4,6-Triaminoquinazoline DHRS4L1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHRS4L1 40013:[DB00480 DB08339] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08339|6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE ABL1 common genes common pathways GO:0007155| cell adhesion ABL1;CDH5 GO:0042127| regulation of cell proliferation ABL1;PTGS2 GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNFSF11 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 40014:[DB00480 DB05362] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05362|SSR-126517E F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 40015:[DB00480 DB05069] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05069|ATG003 CHRNA10;CHRNA9 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;CHRNA10 40016:[DB00480 DB02243] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02243|4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-Amide CTSF common genes common pathways 40017:[DB00480 DB08526] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08526|CARBOBENZYLOXY-(L)-LEUCINYL-(L)LEUCINYL METHOXYMETHYLKETONE CTSH common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CTSH GO:0043066| negative regulation of apoptotic process CTSH;PTGS2 GO:0070371| ERK1 and ERK2 cascade CTSH;TNFSF11 40018:[DB00480 DB06229] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06229|Ocaperidone DRD2;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA1D;ADRA2B;ADRA2C;HTR2A;HTR2B;HTR2C common genes common pathways GO:0006954| inflammatory response PTGS2;HRH1 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;ADRA1A;CDH5 GO:0045987| positive regulation of smooth muscle contraction PTGS2;ADRA1B;ADRA1A;ADRA1D GO:0007613| memory PTGS2;HTR2A;HRH1 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B;HTR2A;ADRA1A;ADRA1D;ADRA2C;HRH1 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug ABCB1;HTR2C;PTGS2;HTR2B;HTR2A;ADRA1A;DRD2 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation ADRA1D;ADRA2A;HTR2B;PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2B;HTR2A GO:0007568| aging HTR2A;ADRA1A;PTGS2 40019:[DB00480 DB04018] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04018|S-Isopropyl-Isothiourea NOS3 common genes common pathways GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;NOS3;CDH5 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 40020:[DB00480 DB02551] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02551|6-[N-(4-Ethyl-1,2,3,4-Tetrahydro-6-Isoquinolinyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLAU GO:0010469| regulation of receptor activity PLAU;TNFSF11 40021:[DB00480 DB02527] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02527|Cyclic Adenosine Monophosphate HCN2;PRKAR1A;PRKAR2B;ABCC4;ABCC5;ABCC11;SLC22A6;SLC22A8;SLC22A7 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;ABCC4 GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0006810| transport ABCB1;ABCC5 GO:0010033| response to organic substance PTGS2;ABCC4 GO:0000086| G2/M transition of mitotic cell cycle PRKAR2B;ABCB1 GO:0055085| transmembrane transport SLC22A7;SLC22A8;SLC22A6;ABCC4;HCN2;ABCC5;ABCB1;ABCC11 GO:0007612| learning PTGS2;PRKAR2B GO:0010243| response to organic nitrogen PTGS2;ABCC4 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;ABCC4 GO:0055114| oxidation-reduction process PTGS2;ABCC4 GO:0042493| response to drug ABCC4;ABCB1;PTGS2 GO:0006631| fatty acid metabolic process PRKAR2B;PTGS2 40022:[DB00480 DB03536] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03536|Benzoyl-Arginine-Alanine-Methyl Ketone CTSF common genes common pathways 40023:[DB00480 DB07954] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways GO:0010469| regulation of receptor activity PDE4D;TNFSF11 GO:0007568| aging PDE4D;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;PDE5A GO:0071260| cellular response to mechanical stimulus PTGS2;PDE2A GO:0001525| angiogenesis PDE3B;PTGS2 40024:[DB00480 DB04795] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04795|Thenoyltrifluoroacetone CES1;SDHA common genes common pathways GO:0055114| oxidation-reduction process PTGS2;SDHA 40025:[DB00480 DB05168] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05168|Vintafolide FOLR2;FOLR3;FOLR1 common genes common pathways GO:0002548| monocyte chemotaxis FOLR2;TNFSF11 GO:0008284| positive regulation of cell proliferation FOLR2;PTGS2 GO:0006954| inflammatory response FOLR2;PTGS2 40026:[DB00480 DB00984] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00984|Nandrolone phenpropionate AR;CYP19A1 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006810| transport AR;ABCB1 GO:0055114| oxidation-reduction process CYP19A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11 40027:[DB00480 DB11605] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0006629| lipid metabolic process PPARA;CYP3A4;PTGS2 GO:0006954| inflammatory response PTGS2;NR1H4 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;PPARA;NR1I2;TNFSF11 GO:0043066| negative regulation of apoptotic process NR1H4;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA;NR1H4 GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP3A5;CYP3A4;CYP3A43 GO:0007043| cell-cell junction assembly CDH5;NR1H4 40028:[DB00480 DB08602] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08602|3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one PDE7A common genes common pathways 40029:[DB00480 DB00522] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00522|Bentiromide HPN common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;HPN 40030:[DB00480 DB02004] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02004|5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 40031:[DB00480 DB05047] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05047|CX717 GRIA4;BDNF;GRIA1;GRIA2;GRIA3 common genes common pathways GO:0010469| regulation of receptor activity BDNF;TNFSF11 GO:0006810| transport GRIA3;ABCB1;GRIA4 40032:[DB00480 DB07614] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07614|PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE HPGDS common genes common pathways GO:0006631| fatty acid metabolic process HPGDS;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;HPGDS GO:0006629| lipid metabolic process HPGDS;PTGS2 GO:0019371| cyclooxygenase pathway HPGDS;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0001516| prostaglandin biosynthetic process HPGDS;PTGS2 40033:[DB00480 DB07838] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07838|(Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE NMT2 common genes common pathways 40034:[DB00480 DB00876] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00876|Eprosartan AGTR1;ABCC2 common genes common pathways GO:0006810| transport ABCB1;ABCC2 GO:0006979| response to oxidative stress ABCC2;PTGS2 GO:0055085| transmembrane transport ABCC2;ABCB1 GO:0042127| regulation of cell proliferation AGTR1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;ABCC2 GO:0042493| response to drug PTGS2;ABCB1;ABCC2 GO:0019722| calcium-mediated signaling AGTR1;TNFSF11 GO:0006855| drug transmembrane transport ABCC2;ABCB1 GO:0050727| regulation of inflammatory response AGTR1;PTGS2 40035:[DB00480 DB01544] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0006810| transport GABRA3;GABRA5;GABRA4;GABRA6;GABRB3;GABRA1;GABRG2;ABCB1 GO:0007568| aging PTGS2;TSPO GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0010042| response to manganese ion PTGS2;TSPO GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP2A6 GO:0042493| response to drug ABCB1;TSPO;UGT1A1;PTGS2;CYP2E1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0006629| lipid metabolic process PTGS2;UGT2B7;CYP3A4;CYP2C9 GO:0043065| positive regulation of apoptotic process TSPO;PTGS2 40036:[DB00480 DB05316] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05316|Pimavanserin HTR2A;DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0007568| aging PTGS2;HTR2A GO:0042493| response to drug PTGS2;HTR2A;DRD2;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 40037:[DB00480 DB05607] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05607|PRX-08066 HTR2B common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2B GO:0042493| response to drug HTR2B;PTGS2;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2B GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 40038:[DB00480 DB03955] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03955|1-deoxymannojirimycin MAN2A1 common genes common pathways 40039:[DB00480 DB08647] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08647|TRAZEOLIDE IGKC common genes common pathways GO:0006955| immune response TNFSF11;IGKC 40040:[DB00480 DB02935] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02935|Diglyme HSP90B1 common genes common pathways GO:0043066| negative regulation of apoptotic process HSP90B1;PTGS2 GO:0071318| cellular response to ATP PTGS2;HSP90B1 40041:[DB00480 DB03125] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03125|2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 40042:[DB00480 DB01192] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP3A4 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0009314| response to radiation PTGS2;OPRM1 GO:0019233| sensory perception of pain PTGS2;OPRD1;OPRM1 GO:0006955| immune response OPRD1;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 40043:[DB00480 DB08861] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08861|DPDPE SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3 40044:[DB00480 DB02140] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02140|N1-(1-Dimethylcarbamoyl-2-Phenyl-Ethyl)-2-Oxo-N4-(2-Pyridin-2-Yl-Ethyl)-Succinamide CTSH common genes common pathways GO:0008284| positive regulation of cell proliferation CTSH;PTGS2 GO:0043066| negative regulation of apoptotic process CTSH;PTGS2 GO:0070371| ERK1 and ERK2 cascade CTSH;TNFSF11 40045:[DB00480 DB04714] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04714|ISOPENTENYL PYROPHOSPHATE ispU;FDPS;GGPS1;ispH common genes common pathways GO:0006629| lipid metabolic process PTGS2;FDPS 40046:[DB00480 DB06979] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06979|5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid HAO1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HAO1 GO:0006979| response to oxidative stress HAO1;PTGS2 40047:[DB00480 DB08402] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08402|2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID PPARG;NCOA2;RXRA common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0007566| embryo implantation RXRA;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RXRA;PPARG;NCOA2 GO:0042493| response to drug PTGS2;ABCB1;PPARG GO:0010033| response to organic substance PTGS2;PPARG 40048:[DB00480 DB08795] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCB1 GO:0006810| transport SLC15A2;ABCB1;SLC15A1 GO:0055085| transmembrane transport SLC15A2;SLC22A5;SLC15A1;ABCB1 40049:[DB00480 DB07340] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07340|N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine AURKB;INCENP common genes common pathways GO:0034644| cellular response to UV AURKB;PTGS2 GO:0007568| aging PTGS2;AURKB 40050:[DB00480 DB09240] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09240|Niludipine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 40051:[DB00480 DB13421] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13421|Edoxudine ALB common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2 40052:[DB00480 DB12023] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12023|Benralizumab IL5RA;FCGR3A common genes common pathways GO:0006955| immune response FCGR3A;TNFSF11 GO:0019221| cytokine-mediated signaling pathway IL5RA;TNFSF11 40053:[DB00480 DB05423] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05423|ORG-34517 NR3C1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 40054:[DB00480 DB06898] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06898|4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol ESR1;NCOA2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11;NCOA2 40055:[DB00480 DB04477] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04477|N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GAPDHS 40056:[DB00480 DB05415] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05415|OSI-461 PDE5A common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;PDE5A 40057:[DB00480 DB04618] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04618|4,6-DIDEOXY-4-{[4-[(4-O-HEXOPYRANOSYLHEXOPYRANOSYL)OXY]-5,6-DIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}HEXOPYRANOSYL-(1->4)HEXOPYRANOSYL-(1->4)HEXOPYRANOSE AMY2A common genes common pathways 40058:[DB00480 DB00431] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00431|Lindane GABRB1;GLRA1;GLRA2;GLRA3;GLRB;GABRB3;GABRR1;PGR;ESR1;NR1I2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0051260| protein homooligomerization TNFSF11;GLRA3;GLRA1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0006810| transport ABCB1;GABRB3;GABRB1;GABRR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;ESR1;NR1I2;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 40059:[DB00480 DB06896] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06896|1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridine-3-carboxamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET 40060:[DB00480 DB03981] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03981|1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid ANXA5;FGF2;HS3ST3A1 common genes common pathways GO:0010469| regulation of receptor activity FGF2;TNFSF11 GO:0043406| positive regulation of MAP kinase activity FGF2;TNFSF11 GO:0010033| response to organic substance ANXA5;PTGS2 GO:0009887| organ morphogenesis FGF2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;FGF2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;FGF2 GO:0043066| negative regulation of apoptotic process ANXA5;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade FGF2;TNFSF11 GO:0030154| cell differentiation TNFSF11;FGF2 GO:0072089| stem cell proliferation ABCB1;FGF2 GO:0001525| angiogenesis FGF2;PTGS2 GO:0007275| multicellular organismal development TNFSF11;FGF2 40061:[DB00480 DB07968] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07968|N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA PYGL common genes common pathways 40062:[DB00480 DB03987] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03987|2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 40063:[DB00480 DB04076] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04076|Hypoxanthine PNP;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0006955| immune response TNFSF11;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;PNP;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 40064:[DB00480 DB06512] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06512|Deramciclane HTR2A;HTR2C;CYP2D6 common genes common pathways GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0007613| memory HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0042493| response to drug HTR2C;ABCB1;HTR2A;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0007568| aging PTGS2;HTR2A 40065:[DB00480 DB07403] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07403|4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE PDK1 common genes common pathways 40066:[DB00480 DB05971] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05971|Archexin AKT1 common genes common pathways GO:0030154| cell differentiation TNFSF11;AKT1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;AKT1 GO:0045907| positive regulation of vasoconstriction AKT1;PTGS2 GO:0007275| multicellular organismal development AKT1;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;AKT1 GO:0043065| positive regulation of apoptotic process PTGS2;AKT1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process AKT1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;AKT1 GO:0006954| inflammatory response PTGS2;AKT1 GO:0007568| aging PTGS2;AKT1 GO:0071456| cellular response to hypoxia AKT1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;AKT1 GO:0006979| response to oxidative stress PTGS2;AKT1 GO:0010033| response to organic substance AKT1;PTGS2 GO:0043066| negative regulation of apoptotic process AKT1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AKT1;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AKT1 GO:0016567| protein ubiquitination CRBN;AKT1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKT1 40067:[DB00480 DB02996] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02996|2-(Thiomethylene)-4-Methylpentanoic Acid ADAM28 common genes common pathways 40068:[DB00480 DB12629] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 40069:[DB00480 DB03821] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03821|2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid ARSA;ARSA common genes common pathways 40070:[DB00480 DB07999] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07999|{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0010033| response to organic substance AKR1B1;PTGS2 40071:[DB00480 DB08856] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08856|DADLE SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1 40072:[DB00480 DB07447] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0006629| lipid metabolic process AKR1D1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AKR1D1 40073:[DB00480 DB08729] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08729|5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide PDE5A common genes common pathways GO:0043406| positive regulation of MAP kinase activity PDE5A;TNFSF11 40074:[DB00480 DB09037] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09037|Pembrolizumab PDCD1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PDCD1 GO:0043065| positive regulation of apoptotic process PTGS2;PDCD1 GO:0007275| multicellular organismal development PDCD1;TNFSF11 40075:[DB00480 DB11752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11752|Bryostatin 1 CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40076:[DB00480 DB03194] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03194|beta-L-methyl-fucose MBL2 common genes common pathways GO:0006979| response to oxidative stress MBL2;PTGS2 40077:[DB00480 DB08878] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08878|Aminopterin DHFR;SLC46A1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR GO:0055085| transmembrane transport ABCB1;SLC46A1 40078:[DB00480 DB14146] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes ABCB1 common pathways GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;PTGS2 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11;OPRD1 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0006810| transport ABCB1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 40079:[DB00480 DB14029] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14029|Furafylline CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 40080:[DB00480 DB03005] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03005|3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 40081:[DB00480 DB04903] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways GO:0006810| transport ABCB1;GABRA3 40082:[DB00480 DB04273] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04273|8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine PNMT common genes common pathways 40083:[DB00480 DB02831] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02831|Dihydrogenphosphate DCXR common genes common pathways GO:0055114| oxidation-reduction process DCXR;PTGS2 40084:[DB00480 DB00649] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00649|Stavudine pol;ALB;SLC22A6;SLC28A1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC22A6 GO:0098869| PTGS2;ALB GO:0051260| protein homooligomerization SLC22A6;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 40085:[DB00480 DB07406] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07406|(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE MAPKAPK2 common genes common pathways GO:0034097| response to cytokine stimulus MAPKAPK2;PTGS2 GO:0032496| response to lipopolysaccharide MAPKAPK2;PTGS2 GO:0006954| inflammatory response MAPKAPK2;PTGS2 40086:[DB00480 DB00985] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00985|Dimenhydrinate HRH1 common genes common pathways GO:0006954| inflammatory response HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 40087:[DB00480 DB01643] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01643|Thymidine monophosphate tmk;DTYMK;dnaQ;TYMS;thyA;topA common genes common pathways GO:0042493| response to drug ABCB1;TYMS;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;TYMS GO:0007568| aging PTGS2;TYMS GO:0014070| response to organic cyclic compound PTGS2;TYMS GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS 40088:[DB00480 DB00727] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways GO:0008217| regulation of blood pressure NPR1;PTGS2 GO:0055114| oxidation-reduction process ALDH2;PTGS2 40089:[DB00480 DB00785] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00785|Cryptenamine CHRM2;CHRM1;CHRM3;CHRM4;CHRM5 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 40090:[DB00480 DB11952] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11952|Duvelisib PIK3CG;PIK3CD;CYP3A4;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0006810| transport ABCB1;ABCG2 GO:0043406| positive regulation of MAP kinase activity PIK3CG;TNFSF11 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:1901529| ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PIK3CD;PIK3CG GO:0042493| response to drug PTGS2;ABCG2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0030154| cell differentiation TNFSF11;PIK3CD GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0001525| angiogenesis PTGS2;PIK3CG GO:0006954| inflammatory response PIK3CG;PIK3CD;PTGS2 40091:[DB00480 DB05197] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05197|Sofalcone CBR1 common genes common pathways GO:0055114| oxidation-reduction process CBR1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;CBR1 40092:[DB00480 DB07369] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07369|N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;MET 40093:[DB00480 DB00450] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00450|Droperidol DRD2;ADRA1A common genes common pathways GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0042493| response to drug ADRA1A;DRD2;PTGS2;ABCB1 GO:0007568| aging ADRA1A;PTGS2 40094:[DB00480 DB12742] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12742|Amuvatinib KIT;MET;RET;PDGFRA;FLT3;RAD51 common genes common pathways GO:0014070| response to organic cyclic compound RAD51;PTGS2 GO:0030154| cell differentiation TNFSF11;FLT3 GO:0006954| inflammatory response KIT;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity KIT;TNFSF11 GO:0009314| response to radiation KIT;PTGS2 GO:0007275| multicellular organismal development TNFSF11;PDGFRA GO:0043406| positive regulation of MAP kinase activity KIT;FLT3;TNFSF11 GO:0051260| protein homooligomerization RAD51;TNFSF11 GO:0019221| cytokine-mediated signaling pathway KIT;FLT3;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11;PDGFRA;KIT GO:0010243| response to organic nitrogen PTGS2;FLT3 GO:0007156| homophilic cell adhesion CDH5;RET GO:0042493| response to drug ABCB1;RAD51;PTGS2;RET GO:0007155| cell adhesion RET;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET GO:0008284| positive regulation of cell proliferation PTGS2;KIT;PDGFRA;FLT3 GO:0042127| regulation of cell proliferation PTGS2;KIT 40095:[DB00480 DB07920] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07920|N-oxo-2-[(4-phenylphenyl)sulfonylamino]ethanamide MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 40096:[DB00480 DB00737] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00737|Meclizine HRH1;NR1I3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I3 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 40097:[DB00480 DB03828] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03828|RU78299 SRC common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;SRC GO:0034332| adherens junction organization CDH5;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0098609| CDH5;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:1902533| TNFSF11;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0070542| response to fatty acid PTGS2;SRC 40098:[DB00480 DB00433] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00433|Prochlorperazine DRD2;CYP2D6;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0042493| response to drug DRD2;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 40099:[DB00480 DB04098] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04098|Balanol PRKACA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA GO:0034605| cellular response to heat PRKACA;PTGS2 40100:[DB00480 DB01184] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes ABCB1 common pathways GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP1A2;CYP3A4 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:1901529| ABCB1 GO:0007612| learning PTGS2;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;DRD3 GO:0042493| response to drug CYP1A2;ABCB1;DRD3;DRD2;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A7;CYP3A5;PTGS2;CYP2C8;CYP1A2;CYP2D6;CYP2B6;CYP3A4 40101:[DB00480 DB02240] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02240|Quinacrine mustard TPR common genes common pathways GO:0042307| positive regulation of protein import into nucleus PTGS2;TPR GO:0034605| cellular response to heat TPR;PTGS2 40102:[DB00480 DB08240] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08240|N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE ALDOA common genes common pathways 40103:[DB00480 DB08028] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08028|BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE MMP8 common genes common pathways 40104:[DB00480 DB08697] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08697|4-(2-aminoethoxy)-N-(3-chloro-5-piperidin-1-ylphenyl)-3,5-dimethylbenzamide PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLAU GO:0010469| regulation of receptor activity PLAU;TNFSF11 40105:[DB00480 DB06043] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06043|Olaratumab PDGFRA common genes common pathways GO:0007275| multicellular organismal development TNFSF11;PDGFRA GO:0008284| positive regulation of cell proliferation PDGFRA;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRA;TNFSF11 40106:[DB00480 DB08513] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08513|[4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID MAPK1;INSR;IRS1 common genes common pathways GO:0019233| sensory perception of pain PTGS2;MAPK1 GO:0033598| mammary gland epithelial cell proliferation TNFSF11;MAPK1 GO:0070371| ERK1 and ERK2 cascade MAPK1;TNFSF11 GO:0007613| memory INSR;PTGS2 GO:0008284| positive regulation of cell proliferation IRS1;PTGS2;INSR;MAPK1 GO:0032496| response to lipopolysaccharide MAPK1;PTGS2 GO:0007612| learning INSR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade IRS1;INSR;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;INSR GO:0009887| organ morphogenesis MAPK1;TNFSF11;INSR 40107:[DB00480 DB01579] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0042493| response to drug ABCB1;SLC6A2;PTGS2;ADRA1A GO:0007568| aging ADRA1A;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A2;ABCB1 GO:0007275| multicellular organismal development ADRA1B;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;CDH5 40108:[DB00480 DB03848] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03848|Benzenesulfinic acid NR1H2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H2;TNFSF11 40109:[DB00480 DB05964] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0007613| memory SLC6A4;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0042493| response to drug ABCB1;SLC6A4;DRD2;SLC6A2;PTGS2 GO:0006810| transport ABCB1;SLC6A2 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0010033| response to organic substance PTGS2;SLC6A4 40110:[DB00480 DB05129] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05129|Elsamitrucin TOP1;TOP2A common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;TOP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A 40111:[DB00480 DB07359] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07359|3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide GCK common genes common pathways 40112:[DB00480 DB06663] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;SSTR5;SSTR3;SSTR1;SSTR2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:1990830| TNFSF11;SSTR1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 40113:[DB00480 DB07753] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07753|3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TTR;TNFSF11 40114:[DB00480 DB00082] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0019221| cytokine-mediated signaling pathway GHR;TNFSF11 GO:0006631| fatty acid metabolic process GHR;PTGS2;CYP4A11 GO:0042493| response to drug ABCB1;BCHE;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C18;PTGS2;CYP2C19;CYP27A1;CYP4A11 GO:0007612| learning PTGS2;BCHE GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:0051260| protein homooligomerization GLUL;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;GHR GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 40115:[DB00480 DB07875] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07875|5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 40116:[DB00480 DB01034] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01034|Cerulenin fabB;fabF;fabH;FASN common genes common pathways GO:0006631| fatty acid metabolic process FASN;PTGS2 GO:0055114| oxidation-reduction process PTGS2;FASN GO:0006629| lipid metabolic process PTGS2;FASN GO:0006633| fatty acid biosynthetic process FASN;PTGS2 40117:[DB00480 DB07555] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07555|Hydroxy(oxo)(2-{(1S)-2,2,2-trifluoro-1-[2-(trimethylarsonio)ethoxy]ethyl}phenyl)ammonium ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 40118:[DB00480 DB07011] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07011|(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 40119:[DB00480 DB08773] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08773|RALOXIFENE CORE ESR1;NCOA2 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;ESR1;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 40120:[DB00480 DB03867] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03867|Meta-Nitro-Tyrosine GSR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GSR GO:0098869| PTGS2;GSR 40121:[DB00480 DB03568] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03568|Butyric Acid BCHE;BCHE common genes common pathways GO:0007612| learning BCHE;PTGS2 GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;BCHE 40122:[DB00480 DB01861] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01861|Uridine diphosphate glucose GYG1;otsA;GALE;GLT6D1 common genes common pathways 40123:[DB00480 DB03046] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03046|7-Methoxy-8-[1-(Methylsulfonyl)-1h-Pyrazol-4-Yl]Naphthalene-2-Carboximidamide PLAU common genes common pathways GO:0042127| regulation of cell proliferation PLAU;PTGS2 GO:0010469| regulation of receptor activity PLAU;TNFSF11 40124:[DB00480 DB04557] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04557|Arachidonic Acid PTGS1;PPARA;NR1H4;RXRA;CYP2C9;FABP4;ALB;FABP2;SLCO2A1 common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0007566| embryo implantation PTGS2;RXRA GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;PPARA GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0006954| inflammatory response NR1H4;PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| ALB;PTGS2;PTGS1 GO:0007043| cell-cell junction assembly NR1H4;CDH5 GO:0055085| transmembrane transport ABCB1;SLCO2A1 GO:0043066| negative regulation of apoptotic process NR1H4;ALB;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARA;RXRA;NR1H4 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0050728| negative regulation of inflammatory response NR1H4;PPARA;CDH5 GO:0006631| fatty acid metabolic process PPARA;PTGS1;PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2;CYP2C9 40125:[DB00480 DB01692] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01692|Dithioerythritol prfA;TK1 common genes common pathways 40126:[DB00480 DB09300] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09300|Butylscopolamine CHRM3;CHRM2 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 40127:[DB00480 DB03884] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03884|Phenylpyruvic acid HAO1;SLC16A3 common genes common pathways GO:0006979| response to oxidative stress HAO1;PTGS2 GO:0055085| transmembrane transport SLC16A3;ABCB1 GO:0055114| oxidation-reduction process PTGS2;HAO1 40128:[DB00480 DB02082] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02082|Phosphoaminophosphonic Acid Guanylate Ester RAB8B common genes common pathways GO:0034332| adherens junction organization CDH5;RAB8B 40129:[DB00480 DB05831] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05831|ING-1 EPCAM common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EPCAM;TNFSF11 GO:0008284| positive regulation of cell proliferation EPCAM;PTGS2 GO:0098609| CDH5;EPCAM 40130:[DB00480 DB06995] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06995|N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNFSF11 40131:[DB00480 DB07929] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07929|N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE NR1H3;RXRB common genes common pathways GO:0050728| negative regulation of inflammatory response NR1H3;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;TNFSF11;RXRB 40132:[DB00480 DB07479] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07479|(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL POLB common genes common pathways GO:0007568| aging POLB;PTGS2 GO:0006954| inflammatory response PTGS2;POLB 40133:[DB00480 DB03784] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03784|Elaidoylamide PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G2A 40134:[DB00480 DB06199] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06199|Atrasentan EDNRA common genes common pathways GO:0008217| regulation of blood pressure PTGS2;EDNRA 40135:[DB00480 DB08130] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08130|N-(5-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}-1,3,4-oxadiazol-2-yl)ethane-1,2-diamine MAP2K1 common genes common pathways GO:0008285| negative regulation of cell proliferation MAP2K1;CDH5;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAP2K1 40136:[DB00480 DB00028] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00028|Immune Globulin Human FCGR1A;FCGR1B;FCGR2A;FCGR2B;FCGR2C;FCGR3A;FCGR3B;C3;C4A;C4B;C5 common genes common pathways GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;C3;C5 GO:0006629| lipid metabolic process C3;PTGS2 GO:0006955| immune response C3;FCGR3A;FCGR2B;FCGR2C;FCGR3B;FCGR1A;FCGR1B;TNFSF11 GO:0006954| inflammatory response C4A;C5;C4B;FCGR2B;C3;PTGS2 GO:0010469| regulation of receptor activity FCGR2B;TNFSF11 GO:0046330| positive regulation of JNK cascade FCGR2B;TNFSF11 GO:0006631| fatty acid metabolic process PTGS2;C3 40137:[DB00480 DB04622] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04622|N-ACETYLHISTAMINE QPCT common genes common pathways 40138:[DB00480 DB01246] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01246|Alimemazine HRH1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory PTGS2;HRH1 40139:[DB00480 DB00366] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00366|Doxylamine HRH1;CHRM1;NR1I3;CYP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0006954| inflammatory response HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 40140:[DB00480 DB01442] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOA;PTGS2;MAOB GO:0042493| response to drug SLC6A2;PTGS2;MAOB;SLC6A3;HTR2A;ABCB1;SLC6A4 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0010033| response to organic substance PTGS2;SLC6A4 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A2;SLC18A2;SLC18A1;SLC6A3 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2;SLC6A4 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0007568| aging PTGS2;SLC6A3;HTR2A GO:0006810| transport ABCB1;SLC6A2 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006855| drug transmembrane transport SLC18A1;ABCB1 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory SLC6A4;HTR2A;PTGS2 40141:[DB00480 DB06980] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06980|(2S)-2-(1H-indol-3-yl)hexanoic acid SKP1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle SKP1;ABCB1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process SKP1;CRBN GO:0016567| protein ubiquitination SKP1;CRBN 40142:[DB00480 DB07139] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07139|3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid AKR1B1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0010033| response to organic substance PTGS2;AKR1B1 40143:[DB00480 DB07760] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07760|3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid UNG common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;UNG 40144:[DB00480 DB06900] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06900|1-[4-(hydroxymethyl)phenyl]guanidine PRSS8 common genes common pathways 40145:[DB00480 DB06971] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06971|N-{2-[(4'-CYANO-1,1'-BIPHENYL-4-YL)OXY]ETHYL}-N'-HYDROXY-N-METHYLUREA MMP8 common genes common pathways 40146:[DB00480 DB00899] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0009314| response to radiation PTGS2;OPRK1;OPRM1 GO:0019233| sensory perception of pain OPRM1;OPRK1;OPRD1;PTGS2 GO:0006955| immune response TNFSF11;OPRK1;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 40147:[DB00480 DB00218] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 40148:[DB00480 DB13530] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13530|Mepindolol CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 40149:[DB00480 DB08842] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08842|Acetylcarnitine SLC22A5 common genes common pathways GO:0055085| transmembrane transport SLC22A5;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A5 40150:[DB00480 DB03708] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03708|Adenosine 5'-phosphosulfate PAPSS1 common genes common pathways 40151:[DB00480 DB05199] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05199|LX1031 TPH1 common genes common pathways GO:0060749| mammary gland alveolus development TNFSF11;TPH1 GO:0055114| oxidation-reduction process PTGS2;TPH1 40152:[DB00480 DB05882] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05882|CHF 4227 ESR1;ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;ESR2;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;TNFSF11 40153:[DB00480 DB08249] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08249|3,6,9,12,15-PENTAOXATRICOSAN-1-OL DHODH;fadB;fadA common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0014070| response to organic cyclic compound DHODH;PTGS2 GO:0055114| oxidation-reduction process PTGS2;DHODH GO:0042493| response to drug PTGS2;DHODH;ABCB1 40154:[DB00480 DB13165] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways GO:2000114| regulation of establishment of cell polarity ROCK1;CDH5;ROCK2 40155:[DB00480 DB04779] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04779|ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE LCT common genes common pathways 40156:[DB00480 DB03346] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03346|3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol SULT1E1;TTR common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;TTR GO:0006810| transport ABCB1;TTR 40157:[DB00480 DB07208] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07208|(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid PPARG common genes common pathways GO:0010033| response to organic substance PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG 40158:[DB00480 DB09093] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09093|Chlortetracycline rpsC;rpsH;rpsS;rpsN;rpsG;ALB common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 40159:[DB00480 DB07744] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07744|Z-Val-Ala-Asp fluoromethyl ketone CASP1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CASP1 GO:0050727| regulation of inflammatory response CASP1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;CASP1 40160:[DB00480 DB13443] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13443|Esatenolol CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 40161:[DB00480 DB05642] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05642|DDP-225 HTR3A;SLC6A2 common genes common pathways GO:0042493| response to drug PTGS2;SLC6A2;ABCB1 GO:0006810| transport SLC6A2;ABCB1 GO:0055085| transmembrane transport SLC6A2;ABCB1 40162:[DB00480 DB08584] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08584|6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline MET common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNFSF11 40163:[DB00480 DB04859] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04859|Zanapezil ACHE common genes common pathways GO:0007155| cell adhesion ACHE;CDH5 40164:[DB00480 DB12548] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12548|Sparsentan AGT;EDNRA common genes common pathways GO:0070371| ERK1 and ERK2 cascade AGT;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AGT GO:0071260| cellular response to mechanical stimulus AGT;PTGS2 GO:0008217| regulation of blood pressure PTGS2;EDNRA;AGT GO:0008284| positive regulation of cell proliferation PTGS2;AGT GO:0042127| regulation of cell proliferation AGT;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;AGT GO:0010469| regulation of receptor activity TNFSF11;AGT GO:0032355| response to estradiol stimulus PTGS2;AGT GO:0007568| aging AGT;PTGS2 40165:[DB00480 DB00245] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0007568| aging PTGS2;SLC6A3 GO:0055085| transmembrane transport SLC6A3;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2D6 GO:0042493| response to drug SLC6A3;PTGS2;ABCB1 40166:[DB00480 DB07269] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07269|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID CPB1 common genes common pathways 40167:[DB00480 DB00792] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00792|Tripelennamine HRH1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0007613| memory PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006629| lipid metabolic process CYP2D6;PTGS2 GO:0006954| inflammatory response PTGS2;HRH1 40168:[DB00480 DB04447] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04447|1,4-Dithiothreitol acpS;hisD;aroE;LGALS1;CAMK2A;rpmA;ALDH1A1;TRPM7;moaA;MSRA;AXIN1;PPIB;thyA;TPI1;GSTZ1;HMGCR;prfA common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;CAMK2A GO:0006629| lipid metabolic process PTGS2;HMGCR GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade LGALS1;TNFSF11 GO:0007275| multicellular organismal development TPI1;AXIN1;TNFSF11 GO:0007257| activation of JUN kinase activity TNFSF11;AXIN1 GO:0033138| positive regulation of peptidyl-serine phosphorylation AXIN1;PTGS2 GO:0030154| cell differentiation CAMK2A;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0055114| oxidation-reduction process PTGS2;HMGCR;ALDH1A1;MSRA GO:0042493| response to drug ABCB1;LGALS1;PTGS2 GO:0008284| positive regulation of cell proliferation HMGCR;PTGS2 GO:0043066| negative regulation of apoptotic process HMGCR;PTGS2 GO:0046330| positive regulation of JNK cascade AXIN1;TNFSF11 GO:0055085| transmembrane transport ABCB1;TRPM7 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process AXIN1;CRBN GO:0006979| response to oxidative stress PTGS2;MSRA GO:0098869| GSTZ1;PTGS2 GO:0097756| HMGCR;PTGS2 GO:0007568| aging PTGS2;HMGCR 40169:[DB00480 DB05736] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05736|MIV-701 CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 40170:[DB00480 DB07115] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07115|N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide CA13 common genes common pathways 40171:[DB00480 DB03477] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes PTGS2 common pathways GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0034605| cellular response to heat PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug PTGS2;ABCB1 GO:0034097| response to cytokine stimulus PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 40172:[DB00480 DB05295] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05295|Eldecalcitol VDR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VDR GO:0046697| decidualization PTGS2;VDR GO:0009887| organ morphogenesis TNFSF11;VDR GO:0007275| multicellular organismal development VDR;TNFSF11 GO:0008285| negative regulation of cell proliferation PTGS2;VDR;CDH5 40173:[DB00480 DB08566] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08566|D-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 40174:[DB00480 DB03878] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03878|N-[4-Methyl-3-[[4-(3-Pyridinyl)-2-Pyrimidinyl]Amino]Phenyl]-3-Pyridinecarboxamide ABL1 common genes common pathways GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;ABL1 GO:0007155| cell adhesion CDH5;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ABL1;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1 40175:[DB00480 DB05131] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05131|TTP889 F9 common genes common pathways 40176:[DB00480 DB05518] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05518|Managlinat dialanetil FBP1 common genes common pathways 40177:[DB00480 DB07328] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07328|METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 40178:[DB00480 DB08705] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08705|6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PIM1 GO:0007275| multicellular organismal development TNFSF11;PIM1 40179:[DB00480 DB03434] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03434|3[N-Morpholino]Propane Sulfonic Acid GNLY common genes common pathways 40180:[DB00480 DB00429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00429|Carboprost tromethamine PTGER1 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;PTGER1 40181:[DB00480 DB07899] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07899|(2S) N-acetyl-L-alanyl-αL-phenylalanyl-chloroethylketone CTRB1 common genes common pathways 40182:[DB00480 DB00981] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00981|Physostigmine ACHE;CHRNA4;CHRNB2 common genes common pathways GO:0007613| memory CHRNB2;PTGS2 GO:0019233| sensory perception of pain CHRNB2;PTGS2;CHRNA4 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0007612| learning PTGS2;CHRNB2 GO:0007155| cell adhesion CDH5;ACHE 40183:[DB00480 DB05507] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05507|VX-765 CASP1;IL1B common genes common pathways GO:0006954| inflammatory response PTGS2;IL1B GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IL1B GO:0006955| immune response TNFSF11;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;TNFSF11 GO:0050727| regulation of inflammatory response CASP1;PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2;CASP1;IL1B GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;IL1B GO:0031622| positive regulation of fever generation IL1B;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;IL1B;CASP1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;IL1B GO:0007566| embryo implantation PTGS2;IL1B GO:0019221| cytokine-mediated signaling pathway IL1B;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL1B GO:0008284| positive regulation of cell proliferation IL1B;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CASP1;IL1B GO:0046330| positive regulation of JNK cascade TNFSF11;IL1B GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;IL1B GO:0010469| regulation of receptor activity TNFSF11;IL1B 40184:[DB00480 DB03588] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03588|Diphenylacetic Acid CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 40185:[DB00480 DB02103] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02103|2-Chlorodideoxyadenosine HSP90B1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;HSP90B1 GO:0071318| cellular response to ATP PTGS2;HSP90B1 40186:[DB00480 DB02134] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02134|Xanthine gpt;CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 40187:[DB00480 DB07846] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07846|1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 40188:[DB00480 DB06550] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06550|Bivatuzumab CD44 common genes common pathways GO:0007155| cell adhesion CDH5;CD44 GO:0043066| negative regulation of apoptotic process PTGS2;CD44 GO:0098609| CD44;CDH5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CD44 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;CD44 40189:[DB00480 DB08023] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08023|N-cyclohexyl-4-imidazo[1,2-a]pyridin-3-yl-N-methylpyrimidin-2-amine MAPK10 common genes common pathways 40190:[DB00480 DB05804] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes PTGS2 common pathways GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1A2;SLC10A6;SLCO2B1;SLC22A8;ABCB11;SLCO1B1 GO:0034612| response to tumor necrosis factor PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0034605| cellular response to heat PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0046697| decidualization PTGS2 GO:0006810| transport ABCB1;ABCB11 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process CYP3A7;PTGS2;CYP19A1 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 40191:[DB00480 DB04144] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04144|Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone MDM2 common genes common pathways GO:0042493| response to drug PTGS2;MDM2;ABCB1 GO:0016567| protein ubiquitination MDM2;CRBN GO:0008284| positive regulation of cell proliferation PTGS2;MDM2 GO:0043066| negative regulation of apoptotic process MDM2;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;MDM2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;PTGS2 40192:[DB00480 DB07430] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07430|(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one MAPKAPK2 common genes common pathways GO:0006954| inflammatory response PTGS2;MAPKAPK2 GO:0032496| response to lipopolysaccharide PTGS2;MAPKAPK2 GO:0034097| response to cytokine stimulus PTGS2;MAPKAPK2 40193:[DB00480 DB13074] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0050728| negative regulation of inflammatory response CDH5;GHSR GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0046697| decidualization GHSR;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;GHSR 40194:[DB00480 DB03639] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03639|1-Guanidinium-7-Aminoheptane DHPS common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DHPS 40195:[DB00480 DB07563] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07563|1-{7-cyclohexyl-6-[4-(4-methylpiperazin-1-yl)benzyl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl}methanamine CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 40196:[DB00480 DB11133] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes PTGS2 common pathways GO:0071498| cellular response to fluid shear stress PTGS2 GO:0006954| inflammatory response ALOX5;PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0006629| lipid metabolic process PPARA;PPARG;PTGS2;SREBF1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0050727| regulation of inflammatory response PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:1990776| PTGS2 GO:0030728| ovulation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound SREBF1;PTGS2;PPARG GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid SREBF1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0010243| response to organic nitrogen PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process ALOX5;PTGS2 GO:0042493| response to drug PTGS2;SREBF1;PPARG;ABCB1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0034097| response to cytokine stimulus PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;PPARG;TNFSF11;SREBF1 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PPARG;PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0098869| PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0007568| aging SREBF1;PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:1902219| PTGS2 GO:0034605| cellular response to heat PTGS2 40197:[DB00480 DB02376] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02376|D-gluconhydroximo-1,5-lactam LCT common genes common pathways 40198:[DB00480 DB01353] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRNA7;PTGS2 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0006810| transport ABCB1;GABRA1;GABRA4;GABRA6;GRIK2;GABRA5;GABRA3 GO:0055085| transmembrane transport ABCB1;GRIK2 GO:0019233| sensory perception of pain PTGS2;CHRNA4 GO:0007613| memory CHRNA7;PTGS2 40199:[DB00480 DB07845] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07845|2-fluoro-6-{[2-({2-methoxy-4-[(methylsulfonyl)methyl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}benzamide MAPK8 common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;MAPK8 GO:0071260| cellular response to mechanical stimulus PTGS2;MAPK8 GO:0043066| negative regulation of apoptotic process PTGS2;MAPK8 40200:[DB00480 DB04537] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04537|L-Tryptophanamide trpS;WARS common genes common pathways GO:0001525| angiogenesis PTGS2;WARS GO:0008285| negative regulation of cell proliferation WARS;CDH5;PTGS2 40201:[DB00480 DB13934] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13934|Ligandrol AR common genes common pathways GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0006810| transport ABCB1;AR 40202:[DB00480 DB04985] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04985|Tigapotide RPSA common genes common pathways GO:0007155| cell adhesion RPSA;CDH5 40203:[DB00480 DB05141] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05141|LY2181308 BIRC5 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;BIRC5 GO:0008284| positive regulation of cell proliferation BIRC5;PTGS2 GO:0016567| protein ubiquitination CRBN;BIRC5 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;BIRC5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process BIRC5;PTGS2 40204:[DB00480 DB00395] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00395|Carisoprodol GABRA1;GABRB2;GABRG2;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2C19 GO:0006810| transport ABCB1;GABRG2;GABRA1;GABRB2 40205:[DB00480 DB00058] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00058|Alpha-1-proteinase inhibitor ELANE common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;ELANE GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;ELANE GO:0050728| negative regulation of inflammatory response CDH5;ELANE GO:0032496| response to lipopolysaccharide ELANE;PTGS2 40206:[DB00480 DB12301] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP3A5 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40207:[DB00480 DB04398] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04398|Lactic Acid putA;SLC16A7;SLCO2B1;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A10;ABCB1;SLC16A7;SLC16A1;SLCO2A1;SLC16A3;SLCO2B1 GO:0006629| lipid metabolic process PTGS2;SLC16A1 40208:[DB00480 DB06883] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06883|1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea SRC common genes common pathways GO:0098609| SRC;CDH5 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:1902533| SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0034332| adherens junction organization SRC;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0045453| bone resorption SRC;TNFSF11 GO:0070542| response to fatty acid SRC;PTGS2 GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 40209:[DB00480 DB13174] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0050728| negative regulation of inflammatory response NR1H3;CDH5 GO:0019372| lipoxygenase pathway ALOX5;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A7;CYP2E1;ALOX5;CYP3A5;CYP3A4;CYP3A43;CYP1A2;CYP2C9;CYP2D6 GO:0042493| response to drug PTGS2;CYP2E1;ABCB1;CYP1A2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;TNFSF11;NR1H2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006954| inflammatory response PTGS2;ALOX5 GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP2D6;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 40210:[DB00480 DB00100] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00100|Coagulation Factor IX (Recombinant) F10;F11;F7;F8;F2;LRP1;GGCX common genes common pathways GO:0010942| positive regulation of cell death LRP1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;F2;LRP1 GO:0006629| lipid metabolic process LRP1;PTGS2 GO:0014070| response to organic cyclic compound F7;PTGS2 GO:0055114| oxidation-reduction process PTGS2;F8 GO:0051897| positive regulation of protein kinase B signaling cascade F7;TNFSF11;F10 GO:0008284| positive regulation of cell proliferation PTGS2;F2 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0010469| regulation of receptor activity TNFSF11;F2 GO:0007568| aging PTGS2;LRP1 40211:[DB00480 DB07031] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07031|3-Fluoro-4-{[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-2-naphthalenyl)acetyl]amino}benzoic acid RARG common genes common pathways GO:0043065| positive regulation of apoptotic process RARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;RARG;CDH5 GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNFSF11 GO:1990830| RARG;TNFSF11 40212:[DB00480 DB11359] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11359|Guaiacol ALB common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 40213:[DB00480 DB07161] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07161|5-phenyl-1H-indazol-3-amine JAK2 common genes common pathways GO:0030154| cell differentiation TNFSF11;JAK2 GO:0008285| negative regulation of cell proliferation PTGS2;JAK2;CDH5 GO:0050727| regulation of inflammatory response JAK2;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;JAK2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;JAK2 GO:0006979| response to oxidative stress JAK2;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process JAK2;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;JAK2 GO:0042127| regulation of cell proliferation JAK2;PTGS2 GO:0032496| response to lipopolysaccharide JAK2;PTGS2 GO:0008284| positive regulation of cell proliferation JAK2;PTGS2 GO:0019221| cytokine-mediated signaling pathway JAK2;TNFSF11 40214:[DB00480 DB03777] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03777|Rbt205 Inhibitor PIM1;PDPK1;PRKCI common genes common pathways GO:0043066| negative regulation of apoptotic process PIM1;PRKCI;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity PRKCI;TNFSF11 GO:0007275| multicellular organismal development PIM1;TNFSF11 GO:0019722| calcium-mediated signaling TNFSF11;PDPK1 40215:[DB00480 DB03677] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03677|N-Cyclohexyl-N'-Decylurea EPHX2 common genes common pathways GO:0006629| lipid metabolic process EPHX2;PTGS2 GO:0006954| inflammatory response PTGS2;EPHX2 GO:0008217| regulation of blood pressure EPHX2;PTGS2 40216:[DB00480 DB11738] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11738|Rilmenidine ADRA2A common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 40217:[DB00480 DB08009] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08009|5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE CAMK1G common genes common pathways 40218:[DB00480 DB03886] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03886|Biopterin SPR;PTS;DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR;SPR 40219:[DB00480 DB02530] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02530|gamma-Aminobutyric acid GATM;GABBR1;GABBR2;SLC36A1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GATM GO:0055085| transmembrane transport ABCB1;SLC36A1 40220:[DB00480 DB05879] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05879|AME-527 TNF common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TNF GO:0046330| positive regulation of JNK cascade TNFSF11;TNF GO:0042127| regulation of cell proliferation PTGS2;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0010469| regulation of receptor activity TNF;TNFSF11 GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNF;TNFSF11 GO:0010033| response to organic substance PTGS2;TNF GO:0009887| organ morphogenesis TNFSF11;TNF GO:0043065| positive regulation of apoptotic process TNF;PTGS2 GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNF;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TNF GO:0006954| inflammatory response TNF;PTGS2 GO:0006955| immune response TNF;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNF;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;TNF 40221:[DB00480 DB11186] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11186|Pentoxyverine SIGMAR1;KCNH2;OPRK1;OPRM1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0055085| transmembrane transport KCNH2;ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0009314| response to radiation PTGS2;OPRK1;OPRM1 GO:0019233| sensory perception of pain OPRM1;OPRK1;PTGS2 GO:0006955| immune response OPRK1;TNFSF11 40222:[DB00480 DB13877] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13877|Iniparib PARP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5 40223:[DB00480 DB04476] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04476|Trencam-3,2-Hopo LCN2 common genes common pathways 40224:[DB00480 DB08828] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes ABCB1 common pathways GO:0006954| inflammatory response PTGS2;ORM1 GO:0007275| multicellular organismal development TNFSF11;SMO GO:0042307| positive regulation of protein import into nucleus PTGS2;SMO GO:0001503| ossification SMO;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0042493| response to drug ABCG2;PTGS2;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;CYP2C19;PTGS2;CYP3A4;CYP2C9 GO:1901529| ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;SMO GO:0008284| positive regulation of cell proliferation PTGS2;SMO GO:0043066| negative regulation of apoptotic process PTGS2;ALB;SMO GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;ABCG2 GO:0006810| transport ABCB1;ABCG2 GO:0098869| PTGS2;ALB 40225:[DB00480 DB08325] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08325|2-(2-HYDROXYETHYLAMINO)-6-(3-CHLOROANILINO)-9-ISOPROPYLPURINE CSNK1G1;MERTK common genes common pathways 40226:[DB00480 DB07449] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 40227:[DB00480 DB01279] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01279|Galsulfase PLIN3 common genes common pathways 40228:[DB00480 DB00391] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00391|Sulpiride DRD2;DRD3;CA2;CA3;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;DRD2;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;CA2 GO:0071498| cellular response to fluid shear stress PTGS2;CA2 GO:0006979| response to oxidative stress CA3;PTGS2 GO:0045780| positive regulation of bone resorption CA2;TNFSF11 GO:0010033| response to organic substance PTGS2;CA2 GO:0008284| positive regulation of cell proliferation PTGS2;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD3;DRD2 GO:0007612| learning DRD3;BCHE;PTGS2 GO:0042493| response to drug BCHE;ABCB1;DRD3;DRD2;PTGS2 GO:2001225| regulation of chloride transport ABCB1;CA2 40229:[DB00480 DB00388] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;ADRA1B;PTGS2;ADRA1D GO:0045907| positive regulation of vasoconstriction ADRA1A;ADRA1B;PTGS2;ADRA1D GO:0055114| oxidation-reduction process CYP1A2;PTGS2;MAOA GO:0042493| response to drug CYP1A2;ABCB1;ADRA1A;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0008284| positive regulation of cell proliferation ADRA1D;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0007568| aging ADRA1A;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 40230:[DB00480 DB07933] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07933|Erteberel ESR2;ESR1 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1;ESR2 GO:0050727| regulation of inflammatory response PTGS2;ESR1 40231:[DB00480 DB07283] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07283|9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid FABP4 common genes common pathways GO:0050873| brown fat cell differentiation FABP4;PTGS2 GO:0050727| regulation of inflammatory response FABP4;PTGS2 40232:[DB00480 DB08739] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08739|2-{3-[(2S)-4,4-difluoro-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]-3-oxopropyl}-isoindole-1,3(2H)-dione PREP common genes common pathways 40233:[DB00480 DB01159] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0055085| transmembrane transport KCNMA1;ABCB1 GO:0098869| ALB;PTGS2 GO:0051260| protein homooligomerization TNFSF11;GLRA1 GO:0006810| transport ABCB1;GABRG2;GRIN2A;GABRA1;GABRB3;GABRD;GABRB1;GABRA6;GABRA4;GABRA3;GABRA5;GABRB2 GO:0071456| cellular response to hypoxia PTGS2;KCNK3 GO:0010469| regulation of receptor activity KCNK3;TNFSF11 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0055114| oxidation-reduction process MT-ND1;CYP2A6;CYP3A4;CYP2B6;CYP2C9;PTGS2;CYP2E1 GO:0042493| response to drug CYP2E1;PTGS2;KCNK3;ABCB1;MT-ND1;GABRG3;GRIN2A GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0007612| learning PTGS2;GRIN2A GO:0014070| response to organic cyclic compound PTGS2;MT-ND1 GO:0007613| memory PTGS2;GRIN2A GO:0045332| phospholipid translocation KCNN4;ABCB1 GO:0019722| calcium-mediated signaling TNFSF11;GRIN2A GO:0006629| lipid metabolic process CYP3A4;CYP2C9;PTGS2 GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2;KCNMA1 GO:0019233| sensory perception of pain PTGS2;GRIN2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;TNFSF11 40234:[DB00480 DB09085] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09085|Tetracaine RYR1;RYR2 common genes common pathways GO:0007275| multicellular organismal development RYR2;RYR1;TNFSF11 GO:0019722| calcium-mediated signaling RYR2;TNFSF11 GO:0055085| transmembrane transport RYR2;ABCB1;RYR1 40235:[DB00480 DB06560] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06560|Pascolizumab IL4 common genes common pathways GO:0006955| immune response TNFSF11;IL4 GO:0010469| regulation of receptor activity TNFSF11;IL4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL4;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;IL4 40236:[DB00480 DB05889] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes ABCB1 common pathways GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0007155| cell adhesion CDH5;CD22 GO:0042493| response to drug ABCB1;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 40237:[DB00480 DB05367] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05367|Actelion-1 EDNRA common genes common pathways GO:0008217| regulation of blood pressure PTGS2;EDNRA 40238:[DB00480 DB00719] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00719|Azatadine HRH1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory HRH1;PTGS2 40239:[DB00480 DB08499] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08499|N-[3-(2-fluoroethoxy)phenyl]-N'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide CASP3 common genes common pathways GO:0010033| response to organic substance CASP3;PTGS2 GO:0034612| response to tumor necrosis factor PTGS2;CASP3 GO:0032355| response to estradiol stimulus CASP3;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;CASP3 GO:0045786| negative regulation of cell cycle PTGS2;CASP3 GO:0043066| negative regulation of apoptotic process PTGS2;CASP3 GO:0032496| response to lipopolysaccharide CASP3;PTGS2 GO:0014070| response to organic cyclic compound CASP3;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;CASP3 GO:0043065| positive regulation of apoptotic process CASP3;PTGS2 40240:[DB00480 DB01013] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0007568| aging CYP1A1;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;PTGS2;CYP3A4 GO:0042493| response to drug PTGS2;CYP1A1;ABCB1 40241:[DB00480 DB00427] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00427|Triprolidine HRH1 common genes common pathways GO:0006954| inflammatory response PTGS2;HRH1 GO:0007613| memory PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 40242:[DB00480 DB04369] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04369|1,3,2-Dioxaborolan-2-Ol PRSS3 common genes common pathways 40243:[DB00480 DB12020] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12020|Tecovirimat UGT1A1;UGT1A4 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0042493| response to drug UGT1A1;PTGS2;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 40244:[DB00480 DB06235] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;UGT2B7;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 40245:[DB00480 DB04971] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04971|Reglixane PPARA;PPARG common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG;PPARA GO:0010033| response to organic substance PPARG;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;PPARA GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0006631| fatty acid metabolic process PTGS2;PPARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG;PPARA 40246:[DB00480 DB00337] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A GO:0045670| regulation of osteoclast differentiation MTOR;TNFSF11 GO:0071456| cellular response to hypoxia MTOR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process MTOR;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;MTOR GO:0019221| cytokine-mediated signaling pathway TNFSF11;FKBP1A GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;TNFSF11 GO:0010942| positive regulation of cell death PTGS2;MTOR GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade FKBP1A;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40247:[DB00480 DB06470] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2A6;CYP2B6;PTGS2;CYP2C19 GO:0006810| transport ABCB1;GABRA1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40248:[DB00480 DB05092] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05092|CDP323 ITGA4 common genes common pathways GO:0007155| cell adhesion ITGA4;CDH5 40249:[DB00480 DB01340] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0008217| regulation of blood pressure ACE;PTGS2 GO:0042908| xenobiotic transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:1901529| ABCB1 40250:[DB00480 DB05297] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0043066| negative regulation of apoptotic process BCL2;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;BCL2 GO:0034097| response to cytokine stimulus PTGS2;BCL2 GO:0042493| response to drug ABCB1;BCL2;PTGS2 GO:0098609| BCL2;CDH5 GO:0071456| cellular response to hypoxia BCL2;PTGS2 GO:0006979| response to oxidative stress BCL2;PTGS2 GO:0055085| transmembrane transport BCL2;ABCB1 GO:0009887| organ morphogenesis TNFSF11;BCL2 GO:0009314| response to radiation BCL2;PTGS2 GO:0001503| ossification BCL2;TNFSF11 GO:0051384| response to glucocorticoid stimulus PTGS2;BCL2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BCL2 GO:0008285| negative regulation of cell proliferation CDH5;BCL2;PTGS2 40251:[DB00480 DB03738] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03738|Pantothenoylaminoethenethiol PPCDC common genes common pathways 40252:[DB00480 DB08890] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08890|Linaclotide GUCY2C common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;GUCY2C 40253:[DB00480 DB11134] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11134|Cupric oxide ALB;CP common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CP GO:0098869| ALB;PTGS2 40254:[DB00480 DB07285] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways GO:0007566| embryo implantation PTGS2;MMP9 GO:0001503| ossification MMP9;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;MMP9 GO:0043066| negative regulation of apoptotic process MMP9;PTGS2 40255:[DB00480 DB03390] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03390|N-Propyl-Tartramic Acid ACPP common genes common pathways 40256:[DB00480 DB07419] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07419|S-23 AR common genes common pathways GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0006810| transport ABCB1;AR 40257:[DB00480 DB04689] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04689|2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID PPARG common genes common pathways GO:0010033| response to organic substance PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0042493| response to drug ABCB1;PPARG;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG 40258:[DB00480 DB04842] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042493| response to drug ABCB1;DRD2;HTR2A;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0006810| transport CACNG1;ABCB1 GO:0007568| aging HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory HTR2A;PTGS2 40259:[DB00480 DB04577] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04577|1-(1-phenylcyclopentyl)methylamine DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 GO:0007155| cell adhesion CDH5;DPP4 40260:[DB00480 DB04099] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04099|Deamido-Nad+ nadE;NMNAT1;nadD;NMNAT3;nadE;nadE common genes common pathways 40261:[DB00480 DB07069] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07069|3-Hydroxyhippuric acid KYNU common genes common pathways 40262:[DB00480 DB07728] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07728|2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE MAPKAPK2;MAPKAPK3 common genes common pathways GO:0006954| inflammatory response MAPKAPK2;PTGS2 GO:0034097| response to cytokine stimulus MAPKAPK3;MAPKAPK2;PTGS2 GO:0032496| response to lipopolysaccharide MAPKAPK3;MAPKAPK2;PTGS2 40263:[DB00480 DB00509] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00509|Dextrothyroxine THRA;THRB;TPO;SLCO1B1;SLCO1C1;SLCO4A1;SLCO4C1;SLC7A5 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;SLC7A5;SLCO4C1 GO:0001503| ossification THRA;TNFSF11 GO:0030154| cell differentiation TNFSF11;SLC7A5;SLCO4C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TNFSF11;THRA GO:0055114| oxidation-reduction process PTGS2;TPO GO:0006810| transport ABCB1;SLC7A5 GO:0006979| response to oxidative stress TPO;PTGS2 GO:0098869| TPO;PTGS2 GO:0055085| transmembrane transport SLCO1B1;SLCO4A1;SLCO1C1;SLCO4C1;ABCB1 GO:0009887| organ morphogenesis THRA;TNFSF11;THRB 40264:[DB00480 DB11118] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11118|Ammonia GLS2;GLUL;CPS1 common genes common pathways GO:0051384| response to glucocorticoid stimulus CPS1;PTGS2 GO:0032496| response to lipopolysaccharide CPS1;PTGS2 GO:0042493| response to drug CPS1;PTGS2;ABCB1 GO:0051260| protein homooligomerization TNFSF11;GLUL GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;GLUL 40265:[DB00480 DB07882] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07882|4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID IGKC common genes common pathways GO:0006955| immune response IGKC;TNFSF11 40266:[DB00480 DB08766] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08766|Zofenoprilat LAP3 common genes common pathways 40267:[DB00480 DB01809] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0030154| cell differentiation HCK;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;HCK GO:0006954| inflammatory response HCK;PTGS2 GO:0007155| cell adhesion CDH5;RET;HCK GO:0008284| positive regulation of cell proliferation HCK;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HCK GO:0019221| cytokine-mediated signaling pathway TNFSF11;HCK GO:0007156| homophilic cell adhesion RET;CDH5 GO:0042493| response to drug PTGS2;RET;ABCB1 40268:[DB00480 DB02326] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02326|1-Hydroxyamine-2-Isobutylmalonic Acid MMP8 common genes common pathways 40269:[DB00480 DB01765] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01765|(5-Oxo-5,6-Dihydro-Indolo[1,2-a]Quinazolin-7-Yl)-Acetic Acid CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 40270:[DB00480 DB01549] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0042493| response to drug ABCB1;PTGS2;DRD2 40271:[DB00480 DB06788] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06788|Histrelin GNRHR common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GNRHR 40272:[DB00480 DB03612] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03612|3-Hydroxybutyryl-Coenzyme A HADH common genes common pathways GO:0006629| lipid metabolic process HADH;PTGS2 GO:0006631| fatty acid metabolic process HADH;PTGS2 GO:0042493| response to drug ABCB1;HADH;PTGS2 GO:0055114| oxidation-reduction process HADH;PTGS2 40273:[DB00480 DB05271] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0008285| negative regulation of cell proliferation DRD2;PTGS2;CDH5 GO:0007613| memory PTGS2;DRD1 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0042493| response to drug PTGS2;DRD2;DRD1;DRD3;ABCB1 GO:0007612| learning DRD1;PTGS2;DRD3;DRD5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A;DRD3 40274:[DB00480 DB08399] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08399|PICEATANNOL ATP5B common genes common pathways GO:0001525| angiogenesis ATP5B;PTGS2 GO:0006629| lipid metabolic process PTGS2;ATP5B 40275:[DB00480 DB02422] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02422|Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside MAN1B1 common genes common pathways 40276:[DB00480 DB07597] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07597|CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL PNMT common genes common pathways 40277:[DB00480 DB08287] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08287|(1R,2R)-N-(2-Aminoethyl)-2-{[(4-methoxyphenyl)sulfonyl]methyl}cyclohexanecarboxamide CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 40278:[DB00480 DB00904] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00904|Ondansetron HTR3A;HTR4;OPRM1;HTR1A;HTR1B;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP2C9;CYP2E1 common genes common pathways GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;CYP3A7;CYP3A5;PTGS2;CYP1A2;CYP2C9;CYP2D6;CYP3A4 GO:0042493| response to drug PTGS2;CYP2E1;HTR1B;ABCB1;CYP1A2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2;OPRM1 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;CYP1A2;PTGS2 GO:0009314| response to radiation OPRM1;PTGS2 GO:0019233| sensory perception of pain PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 40279:[DB00480 DB02457] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02457|Undecyl-Phosphinic Acid Butyl Ester LIPF common genes common pathways GO:0055114| oxidation-reduction process LIPF;PTGS2 GO:0006629| lipid metabolic process LIPF;PTGS2 40280:[DB00480 DB04057] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04057|Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor ATIC common genes common pathways 40281:[DB00480 DB08831] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08831|2-deoxyglucose SLC2A1 common genes common pathways GO:0055085| transmembrane transport SLC2A1;ABCB1 GO:0042908| xenobiotic transport SLC2A1;ABCB1 GO:0071260| cellular response to mechanical stimulus PTGS2;SLC2A1 40282:[DB00480 DB12323] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12323|Radotinib ABL1 common genes common pathways GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ABL1 GO:0043065| positive regulation of apoptotic process PTGS2;ABL1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ABL1 GO:0006979| response to oxidative stress ABL1;PTGS2 GO:0042127| regulation of cell proliferation ABL1;PTGS2 GO:0007155| cell adhesion CDH5;ABL1 40283:[DB00480 DB01840] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01840|2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate ISYNA1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;ISYNA1 40284:[DB00480 DB02308] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02308|4-(1,3,2-Dioxaborolan-2-Yloxy)Butan-1-Aminium PRSS3 common genes common pathways 40285:[DB00480 DB02358] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02358|LY374571 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MTHFD1 40286:[DB00480 DB12483] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes ABCB1 common pathways GO:0098869| ALB;PTGS2 GO:0006810| transport ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLC47A2;ABCB1;ABCG2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:1901529| ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CA;TNFSF11;PIK3CD GO:0055114| oxidation-reduction process CYP3A7;CYP3A5;PTGS2;CYP3A43;CYP3A4 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCG2;PTGS2;ABCB1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PIK3CA;PTGS2 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0030154| cell differentiation PIK3CD;TNFSF11 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC47A2;ABCG2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0001525| angiogenesis PIK3CA;PTGS2 GO:0006954| inflammatory response PIK3CA;PTGS2;PIK3CD 40287:[DB00480 DB04864] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04864|Huperzine A ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 40288:[DB00480 DB06834] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06834|N-(2-hydroxy-1,1-dimethylethyl)-1-methyl-3-(1H-pyrrolo[2,3-b]pyridin-2-yl)-1H-indole-5-carboxamide SYK common genes common pathways GO:0009887| organ morphogenesis TNFSF11;SYK GO:0045780| positive regulation of bone resorption TNFSF11;SYK GO:0006954| inflammatory response PTGS2;SYK GO:0001525| angiogenesis PTGS2;SYK GO:0007257| activation of JUN kinase activity TNFSF11;SYK 40289:[DB00480 DB07715] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07715|Emodin CSNK2A1;fabZ;AHR common genes common pathways GO:0008284| positive regulation of cell proliferation CSNK2A1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AHR GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 40290:[DB00480 DB08691] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08691|ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate CLK1;CLK3 common genes common pathways 40291:[DB00480 DB00161] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00161|L-Valine PCCB;BCAT1;VARS;VARS;PCCB;BCAT1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 40292:[DB00480 DB05152] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05152|NGX267 CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 40293:[DB00480 DB01940] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01940|Balanol Analog 2 PRKACA common genes common pathways GO:0034605| cellular response to heat PTGS2;PRKACA GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PRKACA 40294:[DB00480 DB01931] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways GO:0019722| calcium-mediated signaling GRIN1;TNFSF11 GO:0007613| memory GRIN1;PTGS2 GO:0055074| calcium ion homeostasis GRIN1;TNFSF11 GO:0043065| positive regulation of apoptotic process GRIN1;PTGS2 GO:0019233| sensory perception of pain PTGS2;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 GO:0007612| learning GRIN1;PTGS2 40295:[DB00480 DB04954] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04954|Tecadenoson ADORA1 common genes common pathways GO:0006954| inflammatory response ADORA1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;ADORA1;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;ADORA1 GO:0050728| negative regulation of inflammatory response CDH5;ADORA1 GO:0097756| PTGS2;ADORA1 40296:[DB00480 DB01189] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes common pathways GO:0014070| response to organic cyclic compound MT-ND1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;TNFSF11 GO:0055085| transmembrane transport KCNA1;ABCB1 GO:0006810| transport GABRA1;GABRB3;ABCB1;GABRG2;GABRB2;GABRA5;GABRA3;GABRD;GABRA6;GABRA4;GABRB1 GO:0051260| protein homooligomerization TNFSF11;KCNA1;GLRA1 GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process MT-ND1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;MT-ND1;GABRG3 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 40297:[DB00480 DB05110] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05110|VIR201 IFNG common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process IFNG;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;IFNG GO:0008284| positive regulation of cell proliferation PTGS2;IFNG GO:0006955| immune response IFNG;TNFSF11 GO:0045672| positive regulation of osteoclast differentiation IFNG;TNFSF11 40298:[DB00480 DB04307] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04307|5-Hydroxy-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0042493| response to drug MAOB;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;MAOB 40299:[DB00480 DB04899] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04899|Nesiritide NPR1;NPR2;NPR3 common genes common pathways GO:0001503| ossification TNFSF11;NPR2 GO:0008217| regulation of blood pressure NPR2;NPR1;NPR3;PTGS2 GO:0002158| osteoclast proliferation TNFSF11;NPR3 40300:[DB00480 DB05829] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05829|Parathyroid hormone PTH1R;PTH2R common genes common pathways GO:0008284| positive regulation of cell proliferation PTH1R;PTGS2 GO:0030282| bone mineralization PTH1R;PTGS2 GO:0007568| aging PTGS2;PTH1R GO:0001503| ossification PTH1R;TNFSF11 GO:0045453| bone resorption PTH1R;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;PTH1R 40301:[DB00480 DB06194] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06194|Elocalcitol VDR common genes common pathways GO:0008285| negative regulation of cell proliferation VDR;PTGS2;CDH5 GO:0007275| multicellular organismal development VDR;TNFSF11 GO:0046697| decidualization PTGS2;VDR GO:0009887| organ morphogenesis TNFSF11;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 40302:[DB00480 DB12116] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AHR GO:0042127| regulation of cell proliferation PTGS2;DNMT1 40303:[DB00480 DB02104] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02104|2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine DHFR common genes common pathways GO:0055114| oxidation-reduction process DHFR;PTGS2 40304:[DB00480 DB05846] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05846|Mito-4509 APP common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;APP GO:0019722| calcium-mediated signaling APP;TNFSF11 GO:0007613| memory PTGS2;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TNFSF11 GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0006979| response to oxidative stress APP;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;PTGS2 GO:0051260| protein homooligomerization APP;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade APP;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;TNFSF11 GO:0007155| cell adhesion APP;CDH5 GO:0007612| learning PTGS2;APP GO:0046330| positive regulation of JNK cascade APP;TNFSF11 40305:[DB00480 DB08802] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08802|Isothipendyl HRH1 common genes common pathways GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 40306:[DB00480 DB02035] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02035|1-Hexadecylsulfonyl Fluoride PPT1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PPT1 40307:[DB00480 DB01051] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01051|Novobiocin gyrB;topA;SLC22A6;SLC22A8;SLC22A11;ABCG2;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0042493| response to drug ABCB1;ABCG2;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006810| transport ABCG2;ABCB1 GO:0055085| transmembrane transport SLC22A11;ABCG2;SLCO1B1;SLC22A8;SLC22A6;SLCO2B1;ABCB1;SLCO1B3 40308:[DB00480 DB13919] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13919|Candesartan AGTR1;CYP2C8;CYP2C9;UGT1A3;PTGS1;ABCB1;SLCO1B1 common genes ABCB1 common pathways GO:0098869| PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0006810| transport ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1B1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation PTGS2;AGTR1;PTGS1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP2C9;PTGS1;PTGS2;CYP2C8 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0019722| calcium-mediated signaling TNFSF11;AGTR1 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1;CYP2C9 GO:0050727| regulation of inflammatory response PTGS2;AGTR1 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 40309:[DB00480 DB04891] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04891|Becocalcidiol MED1;VDR common genes common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;MED1 GO:0033598| mammary gland epithelial cell proliferation TNFSF11;MED1 GO:0007275| multicellular organismal development MED1;TNFSF11;VDR GO:0001525| angiogenesis MED1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;VDR;PTGS2 GO:0016567| protein ubiquitination CRBN;MED1 GO:0043066| negative regulation of apoptotic process MED1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;MED1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11;MED1 GO:0009887| organ morphogenesis VDR;MED1;TNFSF11 GO:0046697| decidualization PTGS2;VDR 40310:[DB00480 DB00610] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00610|Metaraminol ADRA1A common genes common pathways GO:0007568| aging PTGS2;ADRA1A GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0045907| positive regulation of vasoconstriction ADRA1A;PTGS2 GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 40311:[DB00480 DB02597] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02597|[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala MME common genes common pathways GO:0019233| sensory perception of pain MME;PTGS2 40312:[DB00480 DB02309] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 40313:[DB00480 DB13978] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13978|Selisistat SIRT1 common genes common pathways GO:0016567| protein ubiquitination SIRT1;CRBN GO:0042127| regulation of cell proliferation SIRT1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;SIRT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;SIRT1 GO:0043066| negative regulation of apoptotic process PTGS2;SIRT1 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SIRT1 GO:1990830| TNFSF11;SIRT1 GO:0071456| cellular response to hypoxia PTGS2;SIRT1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process SIRT1;CRBN GO:0006979| response to oxidative stress PTGS2;SIRT1 GO:0001525| angiogenesis SIRT1;PTGS2 GO:0007275| multicellular organismal development SIRT1;TNFSF11 GO:0043065| positive regulation of apoptotic process SIRT1;PTGS2 GO:0030154| cell differentiation SIRT1;TNFSF11 40314:[DB00480 DB02547] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02547|Guanosine-5'-Diphosphate-Rhamnose GMDS common genes common pathways 40315:[DB00480 DB03573] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03573|WRR-99 CTSF common genes common pathways 40316:[DB00480 DB06429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06429|Talnetant TACR3 common genes common pathways GO:0007568| aging PTGS2;TACR3 GO:0032355| response to estradiol stimulus TACR3;PTGS2 40317:[DB00480 DB00644] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00644|Gonadorelin GNRHR;GNRHR2 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GNRHR 40318:[DB00480 DB04927] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04927|NM100060 SQLE common genes common pathways GO:0010033| response to organic substance SQLE;PTGS2 GO:0055114| oxidation-reduction process PTGS2;SQLE 40319:[DB00480 DB02834] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02834|IDD552 AKR1B1 common genes common pathways GO:0010033| response to organic substance AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 40320:[DB00480 DB14543] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes ABCB1 common pathways GO:0042493| response to drug ANXA1;HSD11B2;ABCB1;ABCG2;PTGS2 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP11B2;PTGS2;CYP2C8;CYP11B1;CYP3A7;HSD3B1;CYP3A5;CYP3A4;HSD11B2 GO:2001225| regulation of chloride transport ABCB1 GO:0002548| monocyte chemotaxis ANXA1;TNFSF11 GO:1901529| ABCB1 GO:0042127| regulation of cell proliferation ANXA1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCG2;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0098609| ANXA1;CDH5 GO:0032355| response to estradiol stimulus ANXA1;PTGS2 GO:0006810| transport ABCB1;ABCG2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;ANXA1 GO:0006955| immune response CYP11B1;TNFSF11 GO:0006954| inflammatory response PTGS2;ANXA1 GO:0050727| regulation of inflammatory response PTGS2;ANXA1 GO:0043065| positive regulation of apoptotic process ANXA1;PTGS2 GO:0006629| lipid metabolic process CYP11B1;CYP11B2;PTGS2;CYP3A4 GO:0014070| response to organic cyclic compound PTGS2;ANXA1 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2;ANXA1 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0008217| regulation of blood pressure PTGS2;CYP11B1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0051384| response to glucocorticoid stimulus ANXA1;HSD11B2;PTGS2 GO:0042908| xenobiotic transport ABCG2;ABCB1 40321:[DB00480 DB07641] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07641|Decyl(dimethyl)phosphine oxide MAOA common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOA 40322:[DB00480 DB04235] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04235|4-Amino Hexanoic Acid ABAT common genes common pathways GO:0042493| response to drug ABCB1;ABAT;PTGS2 GO:0007568| aging ABAT;PTGS2 40323:[DB00480 DB00389] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00389|Carbimazole TPO;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process TPO;CYP19A1;PTGS2 GO:0098869| PTGS2;TPO GO:0006979| response to oxidative stress TPO;PTGS2 40324:[DB00480 DB01164] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01164|Calcium Chloride S100A13 common genes common pathways GO:0008284| positive regulation of cell proliferation S100A13;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;S100A13 40325:[DB00480 DB06678] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0006954| inflammatory response PTGS2;HRH1 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;HRH1;ADRA2C GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0007613| memory HRH1;HTR2A;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug HTR2A;HTR2B;PTGS2;HTR2C;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0008284| positive regulation of cell proliferation ADRA2A;HTR2B;PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;ADRA2A;TNFSF11 GO:0007568| aging PTGS2;HTR2A 40326:[DB00480 DB08703] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08703|12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one MAP3K9 common genes common pathways GO:0007257| activation of JUN kinase activity MAP3K9;TNFSF11 GO:0043065| positive regulation of apoptotic process MAP3K9;PTGS2 40327:[DB00480 DB00740] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0006979| response to oxidative stress PTGS2;SLC7A11 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0007568| aging CYP1A1;PTGS2 GO:0006810| transport ABCG2;ABCB1 GO:0010033| response to organic substance CYP1A2;CYP1A1;PTGS2 GO:0055085| transmembrane transport ABCG2;SCN5A;ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;ABCG2;PTGS2;CYP1A1 GO:0055114| oxidation-reduction process CYP1A1;PTGS2;CYP1A2 40328:[DB00480 DB06941] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06941|(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide S100B common genes common pathways GO:0008284| positive regulation of cell proliferation S100B;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;S100B GO:0043065| positive regulation of apoptotic process PTGS2;S100B GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;S100B GO:0051384| response to glucocorticoid stimulus S100B;PTGS2 GO:0007613| memory S100B;PTGS2 40329:[DB00480 DB07268] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07268|2-({2-[(3-HYDROXYPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)BENZAMIDE MAPK8 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;MAPK8 GO:0043065| positive regulation of apoptotic process PTGS2;MAPK8 GO:0071260| cellular response to mechanical stimulus MAPK8;PTGS2 40330:[DB00480 DB01482] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01482|Fenethylline CYP1A2 common genes common pathways GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 40331:[DB00480 DB01297] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01297|Practolol ADRB1;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0050873| brown fat cell differentiation ADRB1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 40332:[DB00480 DB11772] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11772|Pilaralisib PIK3CA common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PIK3CA GO:0001525| angiogenesis PTGS2;PIK3CA GO:0006954| inflammatory response PIK3CA;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;PIK3CA 40333:[DB00480 DB02095] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02095|Isatin MAOB;MAOB common genes common pathways GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0055114| oxidation-reduction process MAOB;PTGS2 GO:0042493| response to drug MAOB;PTGS2;ABCB1 40334:[DB00480 DB09568] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09568|Omega-3-carboxylic acids DGAT2;HSD17B10;ECHS1;HADH;ELOVL4;LPL;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP4F2;PCTP;PEBP1 common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;LPL;HADH GO:0006631| fatty acid metabolic process ELOVL4;HADH;PTGS2;ECHS1 GO:0055114| oxidation-reduction process CYP3A7;CYP4F2;CYP3A5;PTGS2;HADH;CYP3A4;HSD17B10;CYP3A43 GO:0006629| lipid metabolic process ELOVL4;HADH;DGAT2;LPL;HSD17B10;CYP3A4;ECHS1;PTGS2 GO:0008217| regulation of blood pressure CYP4F2;PTGS2 GO:0006633| fatty acid biosynthetic process ELOVL4;LPL;PTGS2 40335:[DB00480 DB00297] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP3A4;CYP2C19;PTGS2 GO:0032496| response to lipopolysaccharide PTGER1;PTGS2 GO:0019233| sensory perception of pain SCN10A;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 40336:[DB00480 DB02249] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02249|2-Ethoxyethanol ADH1C common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1C 40337:[DB00480 DB11994] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006954| inflammatory response ALOX5;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2D6;CYP2C9;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0019372| lipoxygenase pathway PTGS2;ALOX5 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0050728| negative regulation of inflammatory response CDH5;NR1H3 GO:0042493| response to drug CYP2E1;PTGS2;CYP1A2;ABCB1 GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP1A2;CYP3A43;CYP3A4;CYP3A5;ALOX5;CYP2E1;CYP3A7;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H3;NR1H2;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 40338:[DB00480 DB04841] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A1;PTGS2;CYP1A2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH1 GO:0007613| memory PTGS2;HRH1 GO:0006954| inflammatory response PTGS2;HRH1 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP1A2;CYP2D6;CYP2C9 GO:0010033| response to organic substance CYP1A2;PTGS2;CYP1A1 GO:0055085| transmembrane transport CACNA1H;CALM1;ABCB1;CACNA1G;CACNA1I GO:0006810| transport ABCB1;CACNA1I GO:0007568| aging CYP1A1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP1A1;CYP3A4;CYP2A6;CYP1A2;CYP2D6;CYP2C9 GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1;CYP1A2 40339:[DB00480 DB05903] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05903|KOS-1584 CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 40340:[DB00480 DB00491] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 40341:[DB00480 DB04556] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04556|3-[(1s)-1-(Dimethylamino)Ethyl]Phenol ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 40342:[DB00480 DB06436] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06436|Semaxanib KDR;PTGS2 common genes PTGS2 common pathways GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0030154| cell differentiation TNFSF11;KDR GO:0007613| memory PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0008217| regulation of blood pressure PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2 GO:0030728| ovulation PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2;KDR GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0007275| multicellular organismal development TNFSF11;KDR GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0019371| cyclooxygenase pathway PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2 GO:0006979| response to oxidative stress PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0045786| negative regulation of cell cycle PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS2 GO:0007612| learning PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 40343:[DB00480 DB04970] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04970|Lesopitron HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A 40344:[DB00480 DB00335] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB11;ABCB1 GO:0006810| transport ABCB1;ABCB11 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:1901529| ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0050873| brown fat cell differentiation PTGS2;ADRB1;ADRB2 40345:[DB00480 DB06867] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06867|3,6,9,12,15,18-HEXAOXAICOSANE PIN1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PIN1 40346:[DB00480 DB07412] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07412|1-biphenyl-2-ylmethanamine DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 40347:[DB00480 DB02710] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02710|2,3,-Dihydroxybenzoylserine LCN2 common genes common pathways 40348:[DB00480 DB01681] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01681|Benzene Hexacarboxylic Acid PGAM2 common genes common pathways 40349:[DB00480 DB08492] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08492|(2E)-3-(2-OCT-1-YN-1-YLPHENYL)ACRYLIC ACID ALOX15 common genes common pathways GO:0006954| inflammatory response PTGS2;ALOX15 GO:0001503| ossification TNFSF11;ALOX15 GO:0006629| lipid metabolic process ALOX15;PTGS2 GO:0030282| bone mineralization PTGS2;ALOX15 GO:0019372| lipoxygenase pathway PTGS2;ALOX15 GO:0055114| oxidation-reduction process PTGS2;ALOX15 GO:0006631| fatty acid metabolic process ALOX15;PTGS2 40350:[DB00480 DB02504] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02504|[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G2A 40351:[DB00480 DB07076] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07076|6-[(Z)-AMINO(IMINO)METHYL]-N-[3-(CYCLOPENTYLOXY)PHENYL]-2-NAPHTHAMIDE PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLAU GO:0010469| regulation of receptor activity PLAU;TNFSF11 40352:[DB00480 DB08651] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08651|3'-THIO-THYMIDINE-5'-PHOSPHATE TOP2B common genes common pathways 40353:[DB00480 DB07271] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07271|4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one DPP4 common genes common pathways GO:0007155| cell adhesion DPP4;CDH5 GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 40354:[DB00480 DB00752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;MAOB;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;MAOB;CYP2E1 GO:0055114| oxidation-reduction process CYP2C19;MAOA;PTGS2;MAOB;CYP2E1;CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 40355:[DB00480 DB09013] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0050873| brown fat cell differentiation ADRB1;PTGS2;ADRB2 GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 40356:[DB00480 DB00277] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5 GO:0055085| transmembrane transport SLC22A7;ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A1;CYP1A2 GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;PDE5A GO:0007568| aging ADA;CYP1A1;PTGS2 GO:0097756| ADORA1;PTGS2 GO:0034605| cellular response to heat PTGS2;HDAC2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP1B1;CYP1A2;CYP2D6;PTGS2;CYP2C8;CYP2E1;CYP1A1 GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;PDE3A;ADA;CYP2E1;ADORA2A;HDAC2;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade CPNE1;TNFSF11 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 GO:0050728| negative regulation of inflammatory response ADA;ADORA2A;ADORA1;CDH5 GO:0032496| response to lipopolysaccharide PTGS2;HDAC2;CYP1A1;CYP1A2 GO:0007155| cell adhesion ADA;CYP1B1;CDH5 GO:0043066| negative regulation of apoptotic process ADORA1;PDE3A;ADA;PTGS2;HDAC2 GO:0008284| positive regulation of cell proliferation PTGS2;HDAC2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1;HDAC2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1;CYP1A2 GO:0008285| negative regulation of cell proliferation CYP1B1;ADORA1;CDH5;ADORA2A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADA;PTGS2 GO:0030154| cell differentiation TNFSF11;CPNE1 GO:0050870| positive regulation of T cell activation TNFSF11;ADA GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ADORA2A;PTGS2 GO:0006954| inflammatory response ADORA2A;PTGS2;ADORA1 GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2;ADORA2B GO:0006629| lipid metabolic process PTGS2;PDE3A;CYP3A4;CPNE1;CYP1A2;CYP2D6 GO:0043065| positive regulation of apoptotic process PTGS2;CYP1B1 40357:[DB00480 DB06856] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06856|6-FLUORO-2-[2-HYDROXY-3-(2-METHYL-CYCLOHEXYLOXY)-PHENYL]-1H-INDOLE-5-CARBOXAMIDINE PLAU common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;PLAU GO:0042127| regulation of cell proliferation PLAU;PTGS2 40358:[DB00480 DB04612] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04612|N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE XIAP common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;XIAP GO:0042127| regulation of cell proliferation XIAP;PTGS2 GO:0016567| protein ubiquitination XIAP;CRBN GO:0050727| regulation of inflammatory response XIAP;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;XIAP 40359:[DB00480 DB03181] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03181|2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TNFSF11 GO:0009887| organ morphogenesis THRB;TNFSF11 40360:[DB00480 DB09302] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09302|Alirocumab PCSK9 common genes common pathways GO:0010469| regulation of receptor activity PCSK9;TNFSF11 GO:0006629| lipid metabolic process PTGS2;PCSK9 40361:[DB00480 DB03906] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03906|2-Phenylheme HMOX1 common genes common pathways GO:0034605| cellular response to heat HMOX1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;HMOX1 GO:0006979| response to oxidative stress HMOX1;PTGS2 GO:0051260| protein homooligomerization HMOX1;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;HMOX1 GO:0048661| positive regulation of smooth muscle cell proliferation HMOX1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;HMOX1 GO:0008285| negative regulation of cell proliferation PTGS2;HMOX1;CDH5 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HMOX1 GO:0001525| angiogenesis HMOX1;PTGS2 GO:0043065| positive regulation of apoptotic process HMOX1;PTGS2 40362:[DB00480 DB13044] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13044|Gossypol BCL2L1 common genes common pathways GO:0043065| positive regulation of apoptotic process BCL2L1;PTGS2 GO:0009314| response to radiation PTGS2;BCL2L1 GO:0034097| response to cytokine stimulus BCL2L1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;BCL2L1 GO:0043066| negative regulation of apoptotic process PTGS2;BCL2L1 40363:[DB00480 DB12789] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12789|Dinoprost PTGDR2 common genes common pathways GO:0006955| immune response TNFSF11;PTGDR2 GO:0019722| calcium-mediated signaling PTGDR2;TNFSF11 40364:[DB00480 DB08321] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08321|(1S,2S,3R,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol MAN2A1 common genes common pathways 40365:[DB00480 DB01852] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01852|Kaempherol UGT3A1 common genes common pathways 40366:[DB00480 DB02235] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02235|L-methionine (R)-S-oxide APP common genes common pathways GO:0007612| learning PTGS2;APP GO:0046330| positive regulation of JNK cascade TNFSF11;APP GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;APP GO:0007155| cell adhesion APP;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;APP GO:0006979| response to oxidative stress PTGS2;APP GO:0045429| positive regulation of nitric oxide biosynthetic process APP;PTGS2 GO:0051260| protein homooligomerization TNFSF11;APP GO:0042327| positive regulation of phosphorylation TNFSF11;APP GO:0043065| positive regulation of apoptotic process PTGS2;APP GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity APP;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TNFSF11 GO:0019722| calcium-mediated signaling APP;TNFSF11 GO:0007613| memory PTGS2;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2 GO:0008285| negative regulation of cell proliferation APP;CDH5;PTGS2 40367:[DB00480 DB05147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05147|CYT997 TUBA1A;TUBA1B;TUBA1C;TUBA4A;TUBA3C;TUBA3E;TUBA4B;TUBB1;TUBB2A;TUBB2B;TUBB4B;TUBB3;TUBB4A;TUBB;TUBB6 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle TUBB4A;TUBB;TUBB4B;TUBA4A;ABCB1;TUBA1A 40368:[DB00480 DB03551] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03551|(3R,4R)-3-Hydroxy-4-(hydroxymethyl)-1-[(4-oxo-4,4a,5,7a-tetrahydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]pyrrolidinium PNP;punA common genes common pathways GO:0006955| immune response TNFSF11;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PNP;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;PNP 40369:[DB00480 DB04043] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04043|Carboxymycobactin T LCN2 common genes common pathways 40370:[DB00480 DB01175] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2;ADRA1A GO:0007613| memory HRH1;SLC6A4;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2D6 GO:0006954| inflammatory response HRH1;PTGS2 GO:0051260| protein homooligomerization SLC6A4;TNFSF11 GO:0007568| aging ADRA1A;SLC6A3;PTGS2 GO:0006810| transport SLC6A2;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A3;SLC6A2 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2D6;CYP3A4 GO:0042493| response to drug SLC6A4;ABCB1;SLC6A3;ADRA1A;PTGS2;SLC6A2 40371:[DB00480 DB13940] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13940|2,5-Dimethoxy-4-ethylthioamphetamine HTR2A;HTR2C common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0042493| response to drug HTR2A;PTGS2;HTR2C;ABCB1 GO:0007568| aging PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A GO:0007613| memory HTR2A;PTGS2 40372:[DB00480 DB05073] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05073|SRT501 SIRT1 common genes common pathways GO:0016567| protein ubiquitination SIRT1;CRBN GO:0042127| regulation of cell proliferation PTGS2;SIRT1 GO:0043066| negative regulation of apoptotic process PTGS2;SIRT1 GO:0008284| positive regulation of cell proliferation SIRT1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;SIRT1 GO:0007179| transforming growth factor beta receptor signaling pathway SIRT1;CDH5 GO:1990830| SIRT1;TNFSF11 GO:0071456| cellular response to hypoxia PTGS2;SIRT1 GO:0006979| response to oxidative stress SIRT1;PTGS2 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process SIRT1;CRBN GO:0007275| multicellular organismal development TNFSF11;SIRT1 GO:0001525| angiogenesis SIRT1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;SIRT1 GO:0030154| cell differentiation TNFSF11;SIRT1 40373:[DB00480 DB07950] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07950|Indoleacetic acid PLA2G2E;SKP1;CCBL1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle SKP1;ABCB1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process SKP1;CRBN GO:0016567| protein ubiquitination CRBN;SKP1 GO:0006954| inflammatory response PLA2G2E;PTGS2 GO:0006629| lipid metabolic process PLA2G2E;PTGS2 40374:[DB00480 DB05010] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05010|SGS-742 GABBR1;GABBR2 common genes common pathways 40375:[DB00480 DB00295] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes ABCB1 common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2;UGT2B7 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;PTGS2 GO:0006954| inflammatory response LY96;PTGS2 GO:0006955| immune response OPRD1;TNFSF11;OPRK1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0042908| xenobiotic transport ABCB1 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0008285| negative regulation of cell proliferation OPRM1;CDH5;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide OPRM1;LY96;PTGS2;UGT1A1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP2D6;CYP3A4 GO:0042493| response to drug ABCB1;PTGS2;UGT1A1 GO:0006631| fatty acid metabolic process PTGS2;UGT1A8 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0006810| transport ABCB1 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 40376:[DB00480 DB01393] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PPARD GO:0043066| negative regulation of apoptotic process PTGS2;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2;RXRB;PPARA;RXRA;PPARG;RXRG GO:0008284| positive regulation of cell proliferation PTGS2;PPARD GO:0006631| fatty acid metabolic process PPARA;PTGS2 GO:0042493| response to drug CYP1A1;PTGS2;PPARG;ABCB1 GO:0055114| oxidation-reduction process CYP1A1;PTGS2;CYP2C8;CYP3A4 GO:0050728| negative regulation of inflammatory response CDH5;PPARD;PPARA GO:0046697| decidualization PPARD;PTGS2 GO:0007568| aging CYP1A1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;PPARD GO:0055085| transmembrane transport SLCO1B1;ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A1;PPARD;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PTGS2;PPARG;PPARD;PPARA;CYP3A4 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0007566| embryo implantation PTGS2;RXRA;PPARD GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0030154| cell differentiation PPARD;TNFSF11 GO:0014070| response to organic cyclic compound PTGS2;CYP1A1;PPARG GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG 40377:[DB00480 DB00089] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00089|Capromab pendetide FOLH1 common genes common pathways 40378:[DB00480 DB04583] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04583|5-Carbamoyl-1,1':4',1''-terphenyl-3-carboxylic acid DHODH common genes common pathways GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 GO:0014070| response to organic cyclic compound DHODH;PTGS2 GO:0042493| response to drug ABCB1;DHODH;PTGS2 GO:0055114| oxidation-reduction process PTGS2;DHODH 40379:[DB00480 DB01675] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01675|Methacrylyl-Coenzyme A ACAD8 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ACAD8 GO:0006629| lipid metabolic process PTGS2;ACAD8 40380:[DB00480 DB09326] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09326|Ammonia N-13 NAGS;RHCG common genes common pathways 40381:[DB00480 DB07457] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07457|3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE PDPK1 common genes common pathways GO:0019722| calcium-mediated signaling TNFSF11;PDPK1 40382:[DB00480 DB07970] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07970|5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide EPHA7 common genes common pathways GO:0007275| multicellular organismal development EPHA7;TNFSF11 GO:0043065| positive regulation of apoptotic process EPHA7;PTGS2 40383:[DB00480 DB07844] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07844|6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 40384:[DB00480 DB07051] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07051|3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER PDE4D common genes common pathways GO:0010469| regulation of receptor activity PDE4D;TNFSF11 GO:0007568| aging PDE4D;PTGS2 40385:[DB00480 DB08207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08207|2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TTR;TNFSF11 40386:[DB00480 DB02924] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02924|(4R)-limonene 1α,2α-epoxide LCN9 common genes common pathways 40387:[DB00480 DB13995] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13995|Ferric pyrophosphate citrate FTL;FTH1;HBA1;HBB common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB GO:0098869| HBB;HBA1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;FTH1 GO:0008285| negative regulation of cell proliferation CDH5;FTH1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;HBB GO:0006955| immune response FTH1;TNFSF11 GO:0010942| positive regulation of cell death HBB;PTGS2;HBA1 40388:[DB00480 DB11572] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11572|Thrombin Alfa F11;F8;F5;F13A1;F13B;FGA;FGB;FGG common genes common pathways GO:0045907| positive regulation of vasoconstriction FGB;FGG;FGA;PTGS2 GO:0055114| oxidation-reduction process PTGS2;F8 40389:[DB00480 DB06795] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06795|Mafenide CA6 common genes common pathways 40390:[DB00480 DB05854] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05854|CLX-0921 PPARG common genes common pathways GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0010033| response to organic substance PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0042493| response to drug ABCB1;PPARG;PTGS2 40391:[DB00480 DB00986] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 40392:[DB00480 DB05443] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05443|ADL 10-0101 OPRK1 common genes common pathways GO:0006955| immune response OPRK1;TNFSF11 GO:0019233| sensory perception of pain OPRK1;PTGS2 GO:0009314| response to radiation OPRK1;PTGS2 40393:[DB00480 DB05098] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05098|Leptin LEPR common genes common pathways GO:0007275| multicellular organismal development LEPR;TNFSF11 GO:0001525| angiogenesis PTGS2;LEPR 40394:[DB00480 DB00217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0045453| bone resorption ADRB2;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA2C GO:0050873| brown fat cell differentiation ADRB2;ADRB3;PTGS2;ADRB1 GO:0007568| aging ADRB3;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 40395:[DB00480 DB09101] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09101|Elvitegravir pol;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40396:[DB00480 DB12202] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12202|Zalutumumab EGFR common genes common pathways GO:0042327| positive regulation of phosphorylation TNFSF11;EGFR GO:0001503| ossification EGFR;TNFSF11 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 GO:0014070| response to organic cyclic compound EGFR;PTGS2 GO:0008284| positive regulation of cell proliferation EGFR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0042127| regulation of cell proliferation PTGS2;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR GO:0006979| response to oxidative stress PTGS2;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0098609| CDH5;EGFR GO:0043406| positive regulation of MAP kinase activity EGFR;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR 40397:[DB00480 DB01090] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;CHRNA10 40398:[DB00480 DB12140] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways GO:0006955| immune response TNF;TNFSF11;IL6;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;IL6;IL1B;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity IL6;IL1B;TNFSF11;TNF GO:0006954| inflammatory response PTGS2;TNF;IL1B;IL6 GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B GO:0043065| positive regulation of apoptotic process TNF;PTGS2;IL6 GO:0045672| positive regulation of osteoclast differentiation TNFSF11;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2 GO:0007275| multicellular organismal development TNFSF11;TNF GO:0031622| positive regulation of fever generation IL1B;TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;IL1B;TNF GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;IL1B GO:0008285| negative regulation of cell proliferation IL1B;IL6;CDH5;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2;IL6 GO:0007566| embryo implantation PTGS2;IL1B GO:0051384| response to glucocorticoid stimulus TNF;PTGS2;IL6 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0019221| cytokine-mediated signaling pathway IL6;IL1B;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2;IL6 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0002548| monocyte chemotaxis TNFSF11;IL6 GO:0043066| negative regulation of apoptotic process PTGS2;IL6 GO:0008284| positive regulation of cell proliferation PTGS2;IL6;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL6;IL1B;TNF GO:0046330| positive regulation of JNK cascade IL1B;TNFSF11;TNF GO:0042127| regulation of cell proliferation TNF;PTGS2 GO:0032496| response to lipopolysaccharide IL1B;PTGS2 GO:0010033| response to organic substance PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0009887| organ morphogenesis TNF;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2;IL1B GO:0045670| regulation of osteoclast differentiation TNFSF11;TNF GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0010469| regulation of receptor activity IL1B;IL6;TNFSF11;TNF 40399:[DB00480 DB08520] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08520|(21S)-1AZA-4,4-DIMETHYL-6,19-DIOXA-2,3,7,20-TETRAOXOBICYCLO[19.4.0] PENTACOSANE FKBP1A common genes common pathways GO:0019221| cytokine-mediated signaling pathway FKBP1A;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FKBP1A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;FKBP1A 40400:[DB00480 DB01291] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01291|Pirbuterol ADRB2;ADRB1 common genes common pathways GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;TNFSF11 GO:0050873| brown fat cell differentiation ADRB2;PTGS2;ADRB1 GO:0045453| bone resorption ADRB2;TNFSF11 40401:[DB00480 DB02054] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02054|Gabaculine OAT common genes common pathways 40402:[DB00480 DB01646] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01646|N-Acetylmethionine RHO common genes common pathways 40403:[DB00480 DB00183] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00183|Pentagastrin CCKBR;BCHE common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;BCHE GO:0007612| learning PTGS2;BCHE GO:0008284| positive regulation of cell proliferation CCKBR;PTGS2 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE 40404:[DB00480 DB02884] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02884|Beta-Cyclohexyl-Alanine ZFY common genes common pathways GO:0007275| multicellular organismal development TNFSF11;ZFY 40405:[DB00480 DB08575] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08575|2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM MME common genes common pathways GO:0019233| sensory perception of pain PTGS2;MME 40406:[DB00480 DB02852] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02852|Domoic Acid GRIK2 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCB1 GO:0006810| transport ABCB1;GRIK2 40407:[DB00480 DB06413] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;CYP2C9;CYP3A4;PTGS2 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;CYP2C9;CYP2B6;CYP3A4;CYP3A5;PTGS2;CYP2C19 GO:0042493| response to drug SLC6A3;PTGS2;CYP1A2;ABCB1 GO:0007568| aging SLC6A3;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC6A3 GO:0010033| response to organic substance CYP1A2;PTGS2 40408:[DB00480 DB08085] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08085|1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE THRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRB;TNFSF11 GO:0009887| organ morphogenesis THRB;TNFSF11 40409:[DB00480 DB07802] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07802|3,8-DIBROMO-7-HYDROXY-4-METHYL-2H-CHROMEN-2-ONE CSNK2A1 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 GO:0008284| positive regulation of cell proliferation CSNK2A1;PTGS2 40410:[DB00480 DB08356] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08356|4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol PDK4 common genes common pathways 40411:[DB00480 DB00542] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug PTGS2;MTHFR;ABCB1 GO:0055114| oxidation-reduction process PTGS2;MTHFR GO:0006810| transport SLC15A2;SLC15A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2 GO:0008217| regulation of blood pressure PTGS2;ACE 40412:[DB00480 DB12391] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12391|Sagopilone CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40413:[DB00480 DB13261] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13261|Sitafloxacin CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 40414:[DB00480 DB01790] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01790|Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate PRKAR1A common genes common pathways 40415:[DB00480 DB08565] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08565|L-1-naphthyl-2-acetamido-ethane boronic acid CTRB1 common genes common pathways 40416:[DB00480 DB03471] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03471|6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G2A 40417:[DB00480 DB07749] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07749|2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE CTRB1 common genes common pathways 40418:[DB00480 DB03207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03207|2-(Biphenyl-4-Sulfonyl)-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid MMP8 common genes common pathways 40419:[DB00480 DB09120] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09120|Zucapsaicin TRPV1;CYP1A2;CYP2C19;CYP2C9;CYP2E1 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0019233| sensory perception of pain PTGS2;TRPV1 GO:0006629| lipid metabolic process TRPV1;PTGS2;CYP1A2;CYP2C9 GO:0043065| positive regulation of apoptotic process PTGS2;TRPV1 GO:0006954| inflammatory response PTGS2;TRPV1 GO:0006810| transport TRPV1;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0034605| cellular response to heat TRPV1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TRPV1 GO:0055085| transmembrane transport ABCB1;TRPV1 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A2 GO:0071318| cellular response to ATP PTGS2;TRPV1 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP2E1;CYP2C9;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2;CYP2E1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1;TRPV1 40420:[DB00480 DB06116] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06116|Eldelumab CXCL10 common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;CXCL10 GO:0042127| regulation of cell proliferation PTGS2;CXCL10 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CXCL10;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;CXCL10 GO:0034605| cellular response to heat PTGS2;CXCL10 GO:0010469| regulation of receptor activity CXCL10;TNFSF11 GO:0006955| immune response TNFSF11;CXCL10 GO:0006954| inflammatory response CXCL10;PTGS2 GO:0033280| response to vitamin D CXCL10;PTGS2 40421:[DB00480 DB05848] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05848|humanized SMART Anti-IL-12 Antibody IL12B common genes common pathways GO:0019233| sensory perception of pain PTGS2;IL12B GO:0045672| positive regulation of osteoclast differentiation TNFSF11;IL12B GO:0010033| response to organic substance IL12B;PTGS2 GO:0010469| regulation of receptor activity IL12B;TNFSF11 40422:[DB00480 DB04036] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04036|Coenzyme a Persulfide IVD common genes common pathways GO:0055114| oxidation-reduction process IVD;PTGS2 40423:[DB00480 DB07240] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07240|3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid TTR common genes common pathways GO:0006810| transport ABCB1;TTR GO:0010469| regulation of receptor activity TNFSF11;TTR 40424:[DB00480 DB00143] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00143|Glutathione MGST3;HPGDS;TXNDC12;GSTA1;GSTA2;MGST1;ESD;GGT1;GSTM2;GLRX;GPX4;GSTM5;GPX6;HAGH;GPX1;GPX8;GPX7;MGST2;GSTO2;GLRX2;GLO1;LTC4S;GSR;GSS;GSTM1;GSTK1;GSTA3;GSTM3;GSTA4;GSTM4;GSTA5;GSTP1;GSTO1;GPX1;GPX2;GSTT1;GSTZ1;GPX5;GPX3;AKR1B1;MMP9;CYP3A4;GSTA2;GSTA1;ABCC1;ABCC2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;GPX1 GO:0019372| lipoxygenase pathway GPX1;LTC4S;GPX4;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation ABCC4;AKR1B1;PTGS2 GO:0010243| response to organic nitrogen MGST3;PTGS2;MGST2;MGST1;ABCC4 GO:0055114| oxidation-reduction process TXNDC12;PTGS2;GPX4;GLRX;GPX3;GPX8;GLRX2;GSTK1;AKR1B1;GPX6;ABCC4;GSTO2;GPX5;CYP3A4;GSTO1;GPX1;GPX2;GPX7;MGST1;GSR GO:0030316| osteoclast differentiation TNFSF11;GLO1 GO:0006631| fatty acid metabolic process PTGS2;GGT1;HPGDS GO:0042493| response to drug ABCC4;ABCB1;ABCC2;MGST1;ABCC1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1;GLO1;GSTP1;GPX1;MMP9 GO:0032496| response to lipopolysaccharide MGST1;ABCC2;PTGS2;MGST2 GO:0010033| response to organic substance ABCC4;AKR1B1;GLRX2;PTGS2 GO:0055085| transmembrane transport ABCC1;ABCC4;ABCC3;ABCB1;ABCC2;ABCC5 GO:0034612| response to tumor necrosis factor PTGS2;GSS GO:0098869| PTGS2;GPX4;GPX3;GPX8;GSTK1;MGST3;GSTM2;GSTA1;GPX6;MGST2;GSTP1;GPX5;GSTO1;GPX1;GPX2;GPX7;GSTZ1;GSTT1;MGST1;GSR;GSTO2;LTC4S GO:0006979| response to oxidative stress GPX3;GPX8;PTGS2;GPX4;GPX6;GPX2;GPX1;GPX5;ABCC2;GSS;GPX7 GO:0006810| transport ABCC5;ABCC2;ABCB1;ABCC3;ABCC1 GO:0007568| aging GLRX2;PTGS2;GSS GO:0032355| response to estradiol stimulus GSTP1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GPX1;PTGS2 GO:0019371| cyclooxygenase pathway HPGDS;PTGS2 GO:0006629| lipid metabolic process MGST2;PTGS2;MGST3;CYP3A4;GPX5;HPGDS;GPX1 GO:0001503| ossification TNFSF11;MMP9 GO:0006693| prostaglandin metabolic process PTGS2;HPGDS GO:0043065| positive regulation of apoptotic process MMP9;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;GGT1 GO:0007275| multicellular organismal development GPX4;TNFSF11 GO:0001516| prostaglandin biosynthetic process HPGDS;PTGS2 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2;ABCC3 GO:0014070| response to organic cyclic compound ABCC4;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0042908| xenobiotic transport ABCC1;ABCC3;ABCB1 GO:0030154| cell differentiation TNFSF11;TXNDC12;GLRX2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0007566| embryo implantation MMP9;PTGS2 40425:[DB00480 DB03466] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03466|BMS184394 RARG common genes common pathways GO:0043065| positive regulation of apoptotic process PTGS2;RARG GO:0008285| negative regulation of cell proliferation RARG;PTGS2;CDH5 GO:0043066| negative regulation of apoptotic process RARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;RARG GO:1990830| TNFSF11;RARG 40426:[DB00480 DB04834] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04834|Rapacuronium CHRM2 common genes common pathways 40427:[DB00480 DB03176] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03176|KB-141 THRB;THRA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;THRB;TNFSF11 GO:0009887| organ morphogenesis THRB;TNFSF11;THRA GO:0001503| ossification THRA;TNFSF11 40428:[DB00480 DB01785] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01785|Dimethylallyl Diphosphate FDPS;IDI1;ispH common genes common pathways GO:0006629| lipid metabolic process FDPS;PTGS2;IDI1 40429:[DB00480 DB14039] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14039|Erenumab CALCRL common genes common pathways GO:0001525| angiogenesis PTGS2;CALCRL GO:0045986| negative regulation of smooth muscle contraction CALCRL;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;CALCRL GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;CALCRL GO:0008284| positive regulation of cell proliferation PTGS2;CALCRL 40430:[DB00480 DB03683] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;MMP9 GO:0007566| embryo implantation MMP9;PTGS2 GO:0043065| positive regulation of apoptotic process MMP9;PTGS2 GO:0001503| ossification TNFSF11;MMP9 40431:[DB00480 DB03393] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03393|(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl- PPIA common genes common pathways 40432:[DB00480 DB01025] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01025|Amlexanox S100A12;S100A13;IL3;FGF1 common genes common pathways GO:0010469| regulation of receptor activity FGF1;TNFSF11;IL3 GO:0034605| cellular response to heat FGF1;PTGS2 GO:1902533| FGF1;TNFSF11 GO:0043406| positive regulation of MAP kinase activity FGF1;TNFSF11;S100A12 GO:0008284| positive regulation of cell proliferation IL3;S100A13;PTGS2;FGF1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;TNFSF11 GO:0002548| monocyte chemotaxis TNFSF11;S100A12 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL3 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGF1 GO:0030154| cell differentiation FGF1;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade S100A13;S100A12;TNFSF11 GO:0001525| angiogenesis PTGS2;FGF1 GO:0007275| multicellular organismal development FGF1;TNFSF11 GO:0006954| inflammatory response S100A12;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity S100A12;TNFSF11 GO:0006955| immune response IL3;TNFSF11 40433:[DB00480 DB03744] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03744|Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate PYGL common genes common pathways 40434:[DB00480 DB01613] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01613|Erythrityl tetranitrate NPR1;NPR2 common genes common pathways GO:0001503| ossification NPR2;TNFSF11 GO:0008217| regulation of blood pressure PTGS2;NPR1;NPR2 40435:[DB00480 DB02016] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02016|R048-8071 LSS common genes common pathways GO:0006629| lipid metabolic process PTGS2;LSS 40436:[DB00480 DB02211] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02211|N-Methyl-N-Propargyl-1(R)-Aminoindan MAOB;MAOB common genes common pathways GO:0055114| oxidation-reduction process PTGS2;MAOB GO:0042493| response to drug PTGS2;MAOB;ABCB1 GO:0032496| response to lipopolysaccharide MAOB;PTGS2 40437:[DB00480 DB01878] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01878|Benzophenone ESR1;ESR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1;ESR2 40438:[DB00480 DB05383] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05383|Pimagedine NOS2;AKR1B1;TIMP3;SLC22A2 common genes common pathways GO:0010033| response to organic substance TIMP3;AKR1B1;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC22A2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation NOS2;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process NOS2;AKR1B1;PTGS2 GO:0006855| drug transmembrane transport ABCB1;SLC22A2 40439:[DB00480 DB03070] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03070|Selenazole-4-Carboxyamide-Adenine Dinucleotide IMPDH2 common genes common pathways GO:0055114| oxidation-reduction process IMPDH2;PTGS2 40440:[DB00480 DB06089] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06089|ICA-105665 KCNQ1;KCNQ3;KCNQ4;KCNQ5;KCNQ2 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNQ3;KCNQ5;KCNQ1;KCNQ4;KCNQ2 40441:[DB00480 DB09119] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0019233| sensory perception of pain P2RX4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0019722| calcium-mediated signaling P2RX4;TNFSF11 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0008217| regulation of blood pressure PTGS2;P2RX4 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 GO:0071318| cellular response to ATP PTGS2;P2RX4 GO:0042493| response to drug ABCB1;PTGS2;UGT1A1 GO:0055114| oxidation-reduction process CYP3A4;CYP2C19;PTGS2 GO:0051260| protein homooligomerization TNFSF11;P2RX4 GO:0045429| positive regulation of nitric oxide biosynthetic process P2RX4;PTGS2 GO:0010033| response to organic substance PTGS2;UGT1A1 40442:[DB00480 DB03929] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0007612| learning PTGS2;GRIN1 GO:0008284| positive regulation of cell proliferation SERPINB3;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;GRIN1 GO:0006810| transport ABCB1;SLC6A14 GO:0051260| protein homooligomerization TNFSF11;GLRA1 GO:0055085| transmembrane transport SLC6A14;SLC16A10;ABCB1 GO:0019233| sensory perception of pain GRIN1;PTGS2 GO:0038001| paracrine signaling SERPINB3;TNFSF11 GO:0043065| positive regulation of apoptotic process GRIN1;PTGS2 GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0007613| memory PTGS2;GRIN1 GO:0019722| calcium-mediated signaling TNFSF11;GRIN1 40443:[DB00480 DB08100] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08100|2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol TTR common genes common pathways GO:0010469| regulation of receptor activity TTR;TNFSF11 GO:0006810| transport TTR;ABCB1 40444:[DB00480 DB04523] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04523|Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 40445:[DB00480 DB04673] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04673|4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 40446:[DB00480 DB04924] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04924|Itopride DRD2;ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0042493| response to drug ABCB1;DRD2;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2 40447:[DB00480 DB12455] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes ABCB1 common pathways GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:0098869| PTGS2;ALB GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:1901529| ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 40448:[DB00480 DB04322] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04322|LY249543 MTHFD1 common genes common pathways GO:0055114| oxidation-reduction process MTHFD1;PTGS2 40449:[DB00480 DB06350] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06350|Elinogrel P2RY12 common genes common pathways GO:0071318| cellular response to ATP P2RY12;PTGS2 40450:[DB00480 DB08039] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08039|(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE CALM1;CAMK2D common genes common pathways GO:0030154| cell differentiation CAMK2D;TNFSF11 GO:0055085| transmembrane transport CALM1;ABCB1 40451:[DB00480 DB13985] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13985|Lutetium Lu 177 dotatate SSTR2;SSTR1;SSTR3;SSTR4;SSTR5 common genes common pathways GO:0008285| negative regulation of cell proliferation SSTR2;SSTR1;PTGS2;CDH5;SSTR5;SSTR4;SSTR3 GO:1990830| TNFSF11;SSTR1 40452:[DB00480 DB04615] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04615|(S)-tacrine(10)-hupyridone ACHE common genes common pathways GO:0007155| cell adhesion CDH5;ACHE 40453:[DB00480 DB01567] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0006810| transport GABRG2;ABCB1;GABRA1;GABRB3;GABRB1;GABRR1;GABRR2;GABRD;GABRA5;GABRA3;GABRB2 GO:0042493| response to drug PTGS2;GABRG3;ABCB1 40454:[DB00480 DB08323] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08323|3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE IGHG2 common genes common pathways 40455:[DB00480 DB03636] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03636|Glycinamid MMP8 common genes common pathways 40456:[DB00480 DB04376] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04376|13-Acetylphorbol PRKCD common genes common pathways GO:0050728| negative regulation of inflammatory response CDH5;PRKCD GO:0010469| regulation of receptor activity TNFSF11;PRKCD GO:0042307| positive regulation of protein import into nucleus PTGS2;PRKCD 40457:[DB00480 DB00771] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00771|Clidinium CHRM1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 40458:[DB00480 DB05468] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05468|R411 ITGA4 common genes common pathways GO:0007155| cell adhesion ITGA4;CDH5 40459:[DB00480 DB07021] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07021|(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation PTGS2;DPP4 40460:[DB00480 DB07226] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07226|N-[4-(2-CHLOROPHENYL)-1,3-DIOXO-1,2,3,6-TETRAHYDROPYRROLO[3,4-C]CARBAZOL-9-YL]FORMAMIDE WEE1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle WEE1;ABCB1 40461:[DB00480 DB06367] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06367|Relacatib CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 40462:[DB00480 DB07202] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07202|6-CHLORO-3-(3-METHYLISOXAZOL-5-YL)-4-PHENYLQUINOLIN-2(1H)-ONE CSF1R common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;CSF1R;CDH5 GO:0006954| inflammatory response PTGS2;CSF1R GO:0007275| multicellular organismal development CSF1R;TNFSF11 GO:0030316| osteoclast differentiation CSF1R;TNFSF11 GO:0019221| cytokine-mediated signaling pathway CSF1R;TNFSF11 GO:0043066| negative regulation of apoptotic process CSF1R;PTGS2 GO:0008284| positive regulation of cell proliferation CSF1R;PTGS2 40463:[DB00480 DB08791] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08791|1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;MET 40464:[DB00480 DB08398] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08398|2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine ESR1;NCOA2 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;NCOA2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 40465:[DB00480 DB00107] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;OXT;OXTR GO:0045907| positive regulation of vasoconstriction PTGS2;OXTR GO:0007613| memory PTGS2;OXT;OXTR GO:0051384| response to glucocorticoid stimulus PTGS2;OXT GO:0070371| ERK1 and ERK2 cascade TNFSF11;OXTR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;OXTR GO:0032355| response to estradiol stimulus OXTR;OXT;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;OXT GO:0042493| response to drug PTGS2;OXTR;ABCB1 GO:0034097| response to cytokine stimulus OXTR;PTGS2 40466:[DB00480 DB00177] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00177|Valsartan AGTR1;CYP2C9;ALB;SLCO1B3;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLCO1B1 GO:0098869| PTGS2;ALB GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0042127| regulation of cell proliferation PTGS2;AGTR1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0019722| calcium-mediated signaling AGTR1;TNFSF11 GO:0050727| regulation of inflammatory response AGTR1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2C9 40467:[DB00480 DB08292] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08292|(5Z)-12-CHLORO-13,15-DIHYDROXY-4,7,8,9-TETRAHYDRO-2-BENZOXACYCLOTRIDECINE-1,10(3H,11H)-DIONE HSP90AB1 common genes common pathways GO:0010033| response to organic substance HSP90AB1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process HSP90AB1;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;HSP90AB1 GO:0043066| negative regulation of apoptotic process PTGS2;HSP90AB1 40468:[DB00480 DB00659] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0019233| sensory perception of pain GRIN2A;PTGS2;GRIN1 GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2;GRIN1 GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 GO:0007613| memory PTGS2;GRIN1;GRIN2A GO:0019722| calcium-mediated signaling GRIN2B;GRIN2A;GRIN2D;TNFSF11;GRIN2C;GRIN1 GO:0007612| learning GRIN2A;PTGS2;GRM5;GRIN1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 GO:0042493| response to drug GABRG3;GRIN2A;ABCB1;PTGS2 GO:0006810| transport GRIN2A;GABRG2;GRIN2B;ABCB1;GABRB3;GABRA1;GABRB1;GABRA4;GABRA6;GRIN2C;GABRD;GABRA3;GABRA5;GABRB2 GO:0055085| transmembrane transport SLC36A1;ABCB1 40469:[DB00480 DB01609] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01609|Deferasirox CYP3A4;UGT1A1;UGT1A3;UGT1A9;CYP2C8;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP3A4 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2;CYP1A2 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP1A2;CYP3A4 GO:0042493| response to drug UGT1A1;PTGS2;CYP1A2;ABCB1 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;CYP1A2 GO:0010033| response to organic substance CYP1A2;PTGS2;UGT1A1 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 40470:[DB00480 DB05540] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05540|Alanosine ADSS;ADSSL1;pyrB;SLC7A11 common genes common pathways GO:0006979| response to oxidative stress PTGS2;SLC7A11 40471:[DB00480 DB03331] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03331|N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine GAPDHS common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GAPDHS 40472:[DB00480 DB09043] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09043|Albiglutide GLP1R common genes common pathways 40473:[DB00480 DB00239] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00239|Oxiconazole NR1I2;CYP3A4;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0042908| xenobiotic transport NR1I2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR1I2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C19 40474:[DB00480 DB00666] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00666|Nafarelin GNRHR;GNRHR2 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GNRHR 40475:[DB00480 DB07697] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07697|1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine PKM common genes common pathways GO:0010033| response to organic substance PKM;PTGS2 40476:[DB00480 DB03959] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03959|N,O6-Disulfo-Glucosamine FGF2;FGF1;HS3ST3A1;HGF;ANXA5 common genes common pathways GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process HGF;PTGS2 GO:0001525| angiogenesis PTGS2;FGF1;FGF2 GO:0007275| multicellular organismal development FGF2;TNFSF11;FGF1 GO:0030154| cell differentiation FGF2;TNFSF11;FGF1 GO:0072089| stem cell proliferation FGF2;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGF2;FGF1;HGF GO:0050728| negative regulation of inflammatory response CDH5;HGF GO:0008284| positive regulation of cell proliferation FGF1;FGF2;PTGS2;HGF GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF1;TNFSF11;FGF2;HGF GO:0043066| negative regulation of apoptotic process HGF;ANXA5;PTGS2 GO:0043406| positive regulation of MAP kinase activity FGF1;FGF2;TNFSF11 GO:0010033| response to organic substance PTGS2;ANXA5 GO:0009887| organ morphogenesis TNFSF11;FGF2 GO:1902533| FGF1;TNFSF11 GO:0010469| regulation of receptor activity HGF;TNFSF11;FGF2;FGF1 GO:0034605| cellular response to heat PTGS2;FGF1 40477:[DB00480 DB01608] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0042493| response to drug PTGS2;DRD1;ABCB1 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation ADRA2A;AR;PTGS2 GO:0007612| learning PTGS2;DRD1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0006810| transport AR;ABCB1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0007275| multicellular organismal development ADRA1B;TNFSF11 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B GO:0007613| memory PTGS2;DRD1 40478:[DB00480 DB06982] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06982|(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid SKP1 common genes common pathways GO:0016567| protein ubiquitination CRBN;SKP1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1;SKP1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;SKP1 40479:[DB00480 DB04224] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04224|Oleic Acid GLTP;PMP2;PPARA;PPARD;RXRA;PPARG;FABP7;FABP4;FABP3;FABP1;ALB;GC common genes common pathways GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation FABP7;PTGS2;CDH5;FABP3;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0070542| response to fatty acid FABP3;PTGS2 GO:0007566| embryo implantation PTGS2;PPARD;RXRA GO:0030154| cell differentiation TNFSF11;PPARD GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process FABP1;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0006629| lipid metabolic process PPARA;PPARD;PPARG;PTGS2 GO:0050873| brown fat cell differentiation PTGS2;FABP4 GO:0010033| response to organic substance PPARG;PPARD;PTGS2 GO:0098869| PTGS2;FABP1;ALB GO:0046697| decidualization PTGS2;PPARD GO:0071456| cellular response to hypoxia PPARD;PTGS2;FABP1 GO:0050728| negative regulation of inflammatory response PPARA;PPARD;CDH5 GO:0006631| fatty acid metabolic process PTGS2;FABP3;PPARA GO:0042493| response to drug ABCB1;FABP3;PPARG;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;FABP1;ALB;PPARD GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;RXRA;PPARG;TNFSF11 GO:0042127| regulation of cell proliferation PPARD;PTGS2 40480:[DB00480 DB06719] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0007275| multicellular organismal development GNRHR;TNFSF11 GO:0045670| regulation of osteoclast differentiation LHCGR;TNFSF11 GO:0055114| oxidation-reduction process CYP19A1;PTGS2 40481:[DB00480 DB14487] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0008217| regulation of blood pressure HBB;AGT;SOD1;PTGS2 GO:0008285| negative regulation of cell proliferation APP;HDAC4;CDH5;PTGS2;NME1;TP53;HDAC1;TP73 GO:0014070| response to organic cyclic compound MGMT;TP53;PTGS2 GO:0042633| hair cycle KRT14;PTGS2;KRT16 GO:0045907| positive regulation of vasoconstriction FGA;PTGS2 GO:0032463| negative regulation of protein homooligomerization CRBN;CLU GO:0070542| response to fatty acid PON1;PTGS2 GO:0034644| cellular response to UV TP73;TP53;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation INS;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0007566| embryo implantation MMP9;PTGS2;SOD1 GO:0051384| response to glucocorticoid stimulus CPN1;PTGS2;APOA2 GO:0030154| cell differentiation TP53;KRT6A;NME1;TNFSF11 GO:0007613| memory APP;PTGS2 GO:0006955| immune response IGKV1-17;IGLV3-21;TNFSF11;C1R;C8A;C8B;IGHA1;JCHAIN;IL3;VTN;C1QC;C3 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JUP;TNFSF11;HDAC4;ESR1;APP GO:0010942| positive regulation of cell death HBA1;PTGS2;MT3;HBB GO:0006954| inflammatory response KNG1;SERPINA3;BDKRB1;C4B;C5;HDAC4;KLKB1;S100A8;KRT16;C3;S100A9;PTGS2 GO:0070371| ERK1 and ERK2 cascade MT3;APOA1;TNFSF11;AGT GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;CLU;INS;AGT;TNFSF11;S100A8;S100A9 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process MDM2;MT3;PTGS2 GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0042307| positive regulation of protein import into nucleus JUP;PTGS2 GO:0043065| positive regulation of apoptotic process MMP9;CLU;APP;KNG1;SOD1;TP53;TP73;PTGS2 GO:0050727| regulation of inflammatory response AHSG;S100A9;PTGS2;S100A8;ESR1;PGLYRP2 GO:0071260| cellular response to mechanical stimulus PTGS2;AGT;HDAC4 GO:0006629| lipid metabolic process APOBR;APOE;APOL1;APOA1;C3;PON1;PTGS2;CLU GO:0001503| ossification AHSG;MMP9;TNFSF11 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2;C3;C5 GO:0019233| sensory perception of pain BDKRB1;PTGS2 GO:0007275| multicellular organismal development TNFSF11;TPI1;HRNR;TP53;F2 GO:0001525| angiogenesis PTGS2;PDCD6;S100A7;FN1 GO:0009887| organ morphogenesis TNFSF11;APLP1 GO:0010033| response to organic substance PTGS2;SOD1 GO:0007179| transforming growth factor beta receptor signaling pathway APOA1;CDH5;PARP1 GO:0055085| transmembrane transport APOA1;ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB;AGT;APP;CLU;ESR1;INS GO:0098869| APOE;HBA1;S100A9;PTGS2;HBB GO:0006979| response to oxidative stress APP;MT3;KRT1;PTGS2;PRDX1;SOD1;TP53;APOE GO:0051260| protein homooligomerization IDE;TNFSF11;GLRA1;APP GO:0043161| proteasomal ubiquitin-dependent protein catabolic process TP53;CRBN GO:0034605| cellular response to heat PTGS2;TP53;PDCD6 GO:0098609| DSP;JUP;CDH5 GO:0010469| regulation of receptor activity INS;TTR;AGT;TNFSF11;DAND5;IL3;F2 GO:0032355| response to estradiol stimulus PTGS2;AGT;ESR1 GO:0006810| transport TTR;ABCB1 GO:0007568| aging SOD1;KRT14;TP53;PTGS2;KRT16;GSN;AGT GO:0097756| INS;PTGS2 GO:0071456| cellular response to hypoxia TP53;MT3;PTGS2;P4HB;MDM2 GO:0019372| lipoxygenase pathway PON1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HDAC4 GO:0010243| response to organic nitrogen TP73;TP53;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;KRT1;APOA1;APOE GO:0051897| positive regulation of protein kinase B signaling cascade APP;INS;TNFSF11 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL3 GO:0006631| fatty acid metabolic process C3;PTGS2 GO:0016567| protein ubiquitination MDM2;CRBN GO:0042493| response to drug APOA2;HDAC4;ABCB1;MDM2;MGMT;TP73;TP53;HDAC1;SOD1;APOA1;NME1;PTGS2 GO:0055114| oxidation-reduction process P4HB;GAPDHS;CCS;CP;ADH1C;PDIA3;SOD1;PRDX1;PTGS2 GO:0034332| adherens junction organization JUP;CDH5;DSP GO:0043066| negative regulation of apoptotic process SOD1;HDAC1;TP53;PTGS2;MT3;MMP9;MGMT;MDM2 GO:0008284| positive regulation of cell proliferation AGT;HDAC4;INS;FN1;MDM2;KRT6A;HDAC1;IL3;PTGS2;F2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;ESR1;APP;TNFSF11;HDAC4;TP53;HDAC1;TP73 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0007155| cell adhesion VTN;CDH5;IGFALS;JUP;FN1;APLP1;APP GO:0034097| response to cytokine stimulus TP53;ITIH4;PTGS2 GO:0071318| cellular response to ATP SOD1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;S100A7;HDAC1;BDKRB1;S100A8 GO:0042127| regulation of cell proliferation AGT;JUP;PTGS2 GO:0007612| learning APP;PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;APP 40482:[DB00480 DB05490] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05490|T131 PPARG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0042493| response to drug ABCB1;PPARG;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 40483:[DB00480 DB11217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11217|Arbutin TYR;ALB common genes common pathways GO:0055114| oxidation-reduction process TYR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0098869| ALB;PTGS2 GO:0033280| response to vitamin D PTGS2;TYR 40484:[DB00480 DB03967] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03967|Dodecyl sulfate LYZ common genes common pathways GO:0006954| inflammatory response PTGS2;LYZ 40485:[DB00480 DB03541] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03541|10-Propargyl-5,8-Dideazafolic Acid thyA;thyA;NQO2;TYMS;DHRS4L1 common genes common pathways GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0042493| response to drug TYMS;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;DHRS4L1;NQO2 GO:0034097| response to cytokine stimulus PTGS2;TYMS GO:0007568| aging TYMS;PTGS2 40486:[DB00480 DB00138] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00138|Cystine SLC7A11;CTNS;SLC7A9;SLC3A1;SLC16A10 common genes common pathways GO:0055085| transmembrane transport CTNS;SLC16A10;ABCB1 GO:0006979| response to oxidative stress SLC7A11;PTGS2 40487:[DB00480 DB05992] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05992|Plinabulin TNF common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;TNF GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNF;TNFSF11 GO:0010469| regulation of receptor activity TNFSF11;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0009887| organ morphogenesis TNFSF11;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TNF GO:0046330| positive regulation of JNK cascade TNF;TNFSF11 GO:0042127| regulation of cell proliferation TNF;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation TNF;PTGS2 GO:0030316| osteoclast differentiation TNFSF11;TNF GO:0033138| positive regulation of peptidyl-serine phosphorylation TNF;PTGS2 GO:0051384| response to glucocorticoid stimulus TNF;PTGS2 GO:0043065| positive regulation of apoptotic process TNF;PTGS2 GO:0045672| positive regulation of osteoclast differentiation TNF;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;TNF GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0031622| positive regulation of fever generation TNF;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNF;TNFSF11 GO:0006955| immune response TNFSF11;TNF GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TNFSF11 GO:0006954| inflammatory response TNF;PTGS2 40488:[DB00480 DB01063] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01063|Acetophenazine DRD2;DRD1;AR common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;AR GO:0007613| memory DRD1;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0006810| transport AR;ABCB1 GO:0042493| response to drug PTGS2;DRD2;DRD1;ABCB1 GO:0007612| learning DRD1;PTGS2 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;DRD2;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;AR 40489:[DB00480 DB00184] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2;CYP1A1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A3;SLC22A5;SLC22A2 GO:0007613| memory CHRNA7;PTGS2;CHRNB2 GO:0019233| sensory perception of pain CHRNB2;CHRNA4;PTGS2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP2C9;CYP2D6;PTGS2 GO:0055085| transmembrane transport SLC22A4;SLC22A1;ABCB1;SLC22A3;SLC22A5;SLC22A2 GO:0010033| response to organic substance CYP1A1;PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0007568| aging CYP1A1;PTGS2 GO:0006810| transport CHRNA6;CHRNB3;ABCB1 GO:0006979| response to oxidative stress CHRNA4;PTGS2 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0042493| response to drug CYP1A2;ABCB1;CYP2E1;CYP1A1;MAOB;PTGS2 GO:0055114| oxidation-reduction process CYP2A6;CYP3A4;CYP1A2;CYP2B6;CYP19A1;CYP2C9;CYP2D6;PTGS2;MAOA;CYP2A13;CYP2C8;CYP2C19;CYP2E1;MAOB;CYP1A1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0042127| regulation of cell proliferation CHRNA10;PTGS2 GO:0007612| learning CHRNB2;PTGS2 GO:0032496| response to lipopolysaccharide MAOB;CYP1A1;PTGS2;CYP1A2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRNA7 40490:[DB00480 DB06777] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways GO:0008284| positive regulation of cell proliferation AKR1C2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1H4;TNFSF11;NR1I2 GO:0043066| negative regulation of apoptotic process PTGS2;NR1H4 GO:0055114| oxidation-reduction process CYP27A1;PTGS2;AKR1C2;CYP3A4 GO:0050728| negative regulation of inflammatory response NR1H4;CDH5 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C2;TNFSF11 GO:0007043| cell-cell junction assembly NR1H4;CDH5 GO:0006693| prostaglandin metabolic process PTGS2;AKR1C2 GO:0006629| lipid metabolic process UGT2B7;PTGS2;CYP3A4;AKR1C2 GO:0006954| inflammatory response NR1H4;PTGS2 GO:0042908| xenobiotic transport ABCB1;NR1I2 40491:[DB00480 DB04310] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04310|2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide def;def;def;def;def;def;def;PDF common genes common pathways GO:0008284| positive regulation of cell proliferation PDF;PTGS2 40492:[DB00480 DB06333] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06333|Trodusquemine PTPN1;SLC6A3;SLC6A2 common genes common pathways GO:0055085| transmembrane transport SLC6A3;SLC6A2;ABCB1 GO:0006810| transport ABCB1;SLC6A2 GO:0007568| aging SLC6A3;PTGS2 GO:0042493| response to drug ABCB1;SLC6A3;PTGS2;SLC6A2 GO:0007257| activation of JUN kinase activity PTPN1;TNFSF11 GO:0014070| response to organic cyclic compound SLC6A3;PTGS2 40493:[DB00480 DB08479] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08479|N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide TYMS common genes common pathways GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0007568| aging PTGS2;TYMS GO:0042493| response to drug ABCB1;TYMS;PTGS2 GO:0034097| response to cytokine stimulus TYMS;PTGS2 40494:[DB00480 DB02108] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02108|2-Aminoethanimidic Acid CTSB common genes common pathways GO:0046697| decidualization PTGS2;CTSB 40495:[DB00480 DB01695] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01695|N-Hydroxy-4-Phosphono-Butanamide TPI1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;TPI1 40496:[DB00480 DB01525] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01525|Ecgonine BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;BCHE;PTGS2 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 40497:[DB00480 DB11591] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11591|Bilastine HRH1;ABCB5;SLCO1A2;SLCO2B1 common genes common pathways GO:0055085| transmembrane transport SLCO2B1;ABCB5;SLCO1A2;ABCB1 GO:0006954| inflammatory response PTGS2;HRH1 GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0030154| cell differentiation ABCB5;TNFSF11 GO:0007613| memory HRH1;PTGS2 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0006855| drug transmembrane transport ABCB5;ABCB1 40498:[DB00480 DB01810] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01810|[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl Ester CTSF common genes common pathways 40499:[DB00480 DB05352] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05352|Fx-1006A TTR common genes common pathways GO:0006810| transport TTR;ABCB1 GO:0010469| regulation of receptor activity TTR;TNFSF11 40500:[DB00480 DB06775] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06775|Carglumic acid CPS1 common genes common pathways GO:0032496| response to lipopolysaccharide CPS1;PTGS2 GO:0042493| response to drug PTGS2;CPS1;ABCB1 GO:0051384| response to glucocorticoid stimulus CPS1;PTGS2 40501:[DB00480 DB05969] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;VEGFA GO:0008284| positive regulation of cell proliferation VEGFA;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;TNFSF11;CDK7 GO:0060749| mammary gland alveolus development TNFSF11;VEGFA GO:0043406| positive regulation of MAP kinase activity TNFSF11;VEGFA GO:0000086| G2/M transition of mitotic cell cycle ABCB1;CDK7 GO:0010469| regulation of receptor activity VEGFA;TNFSF11 GO:0071456| cellular response to hypoxia VEGFA;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;VEGFA GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2;VEGFA GO:0042327| positive regulation of phosphorylation TNFSF11;VEGFA GO:0007275| multicellular organismal development TNFSF11;VEGFA GO:0001525| angiogenesis VEGFA;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation VEGFA;PTGS2 GO:0030154| cell differentiation TNFSF11;VEGFA 40502:[DB00480 DB00809] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 40503:[DB00480 DB02047] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02047|2-(1,1'-Biphenyl-4-Yl)Propanoic Acid PTGS1 common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS2;PTGS1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 40504:[DB00480 DB04879] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04879|Vatalanib FLT1;KDR;FLT4 common genes common pathways GO:0043406| positive regulation of MAP kinase activity TNFSF11;FLT1 GO:0002548| monocyte chemotaxis FLT1;TNFSF11 GO:0046330| positive regulation of JNK cascade FLT4;TNFSF11 GO:0008284| positive regulation of cell proliferation FLT1;PTGS2;FLT4;KDR GO:0043066| negative regulation of apoptotic process KDR;FLT4;PTGS2 GO:0030154| cell differentiation FLT1;KDR;TNFSF11 GO:0070371| ERK1 and ERK2 cascade TNFSF11;KDR GO:0001525| angiogenesis FLT1;FLT4;KDR;PTGS2 GO:0007275| multicellular organismal development TNFSF11;KDR;FLT1 GO:0010575| positive regulation vascular endothelial growth factor production FLT4;PTGS2 40505:[DB00480 DB02303] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02303|(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione DPYD common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DPYD 40506:[DB00480 DB00004] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00004|Denileukin diftitox IL2RA;IL2RB;IL2RG common genes common pathways GO:0006954| inflammatory response IL2RA;PTGS2 GO:0006955| immune response IL2RA;TNFSF11;IL2RG GO:0043066| negative regulation of apoptotic process PTGS2;IL2RB GO:0050728| negative regulation of inflammatory response IL2RA;CDH5 GO:0019221| cytokine-mediated signaling pathway IL2RB;TNFSF11 40507:[DB00480 DB05461] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05461|OPC-28326 HTR2B;ADRA2C;ADRA2B common genes common pathways GO:0045907| positive regulation of vasoconstriction ADRA2C;PTGS2 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2B GO:0008284| positive regulation of cell proliferation PTGS2;HTR2B GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0042493| response to drug ABCB1;PTGS2;HTR2B 40508:[DB00480 DB01238] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;ADRA1B GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 GO:0006954| inflammatory response HRH1;PTGS2 GO:0007613| memory DRD1;HTR2A;PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;ADRA2C;PTGS2;ADRA1B;ADRA1A;HTR2A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2;ADRA1B;CHRM3 GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;DRD2;PTGS2 GO:0007612| learning DRD5;DRD3;PTGS2;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD3;DRD2 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HTR2A;CHRM1;DRD3;ADRA2A GO:0042493| response to drug DRD3;ABCB1;HTR1B;HTR2C;PTGS2;HTR2A;DRD1;ADRA1A;DRD2 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0055114| oxidation-reduction process PTGS2;CYP3A5;CYP3A7;CYP3A4;CYP2D6 GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;ADRA2A;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 40509:[DB00480 DB04849] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04849|Cediranib KDR common genes common pathways GO:0043066| negative regulation of apoptotic process KDR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0030154| cell differentiation KDR;TNFSF11 GO:0007275| multicellular organismal development KDR;TNFSF11 GO:0001525| angiogenesis PTGS2;KDR GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 40510:[DB00480 DB02690] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02690|NU1025 PARP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 40511:[DB00480 DB07312] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07312|2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE FBP1 common genes common pathways 40512:[DB00480 DB02901] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes ABCB1 common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0006629| lipid metabolic process HSD17B1;PTGS2;CYP11A1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006855| drug transmembrane transport ABCB1 GO:0008285| negative regulation of cell proliferation CDH5;AR;PTGS2 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0055114| oxidation-reduction process CYP11A1;CYP19A1;CYP17A1;PTGS2;HSD17B1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:1901529| ABCB1 GO:0060749| mammary gland alveolus development AR;ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11;AR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport AR;ABCB1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 40513:[DB00480 DB00163] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00163|Vitamin E NR1I2;PRKCB;ALOX5;PRKCA;DGKA;PPP2CB;PPP2CA;SEC14L4;SEC14L3;SEC14L2;GSTA2;GSTP1;GSTO1;GSTM3;GCLC;NQO1;HMOX1;SOD1;TTPA common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;PRKCB GO:0006954| inflammatory response ALOX5;PTGS2 GO:0001525| angiogenesis PTGS2;HMOX1;PRKCA GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;PRKCB;HMOX1 GO:0006629| lipid metabolic process PTGS2;TTPA GO:0071260| cellular response to mechanical stimulus GCLC;PTGS2 GO:0043065| positive regulation of apoptotic process HMOX1;SOD1;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;NQO1 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;HMOX1 GO:0008217| regulation of blood pressure PTGS2;SOD1;HMOX1 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0007566| embryo implantation PTGS2;SOD1 GO:0055114| oxidation-reduction process NQO1;GSTO1;PTGS2;ALOX5;SOD1;HMOX1 GO:0042493| response to drug SOD1;PTGS2;ABCB1 GO:0019372| lipoxygenase pathway ALOX5;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;HMOX1 GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0007155| cell adhesion PRKCA;CDH5 GO:0043066| negative regulation of apoptotic process NQO1;GCLC;PTGS2;GSTP1;SOD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TNFSF11 GO:0010033| response to organic substance SOD1;PPP2CA;PTGS2 GO:0007568| aging SOD1;PTGS2;NQO1;GCLC GO:0006810| transport TTPA;ABCB1 GO:0071456| cellular response to hypoxia HMOX1;PTGS2 GO:0034605| cellular response to heat HMOX1;PTGS2 GO:0045780| positive regulation of bone resorption PRKCA;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;GSTP1;NQO1 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process PPP2CB;CRBN GO:0098869| GSTO1;PTGS2;GSTP1 GO:0006979| response to oxidative stress PTGS2;HMOX1;SOD1;GCLC;NQO1 GO:0051260| protein homooligomerization HMOX1;TNFSF11 40514:[DB00480 DB03910] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03910|S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea NOS3 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS3 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0001525| angiogenesis PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation CDH5;NOS3;PTGS2 GO:0008217| regulation of blood pressure NOS3;PTGS2 40515:[DB00480 DB04838] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04838|Cyclandelate CACNA2D1;CES1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 40516:[DB00480 DB06202] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06202|Lasofoxifene ESR1;ESR2;CNR2 common genes common pathways GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0019233| sensory perception of pain PTGS2;CNR2 GO:0006955| immune response CNR2;TNFSF11 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2;ESR1 GO:0006954| inflammatory response CNR2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;ESR2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0032496| response to lipopolysaccharide CNR2;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;CNR2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0032355| response to estradiol stimulus ESR1;PTGS2 40517:[DB00480 DB08798] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08798|Sulfamoxole CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 40518:[DB00480 DB05905] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05905|TD-2749 HTR4 common genes common pathways 40519:[DB00480 DB00496] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;CHRM1 40520:[DB00480 DB04070] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40521:[DB00480 DB00807] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00807|Proparacaine SCN10A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN10A GO:0019233| sensory perception of pain SCN10A;PTGS2 40522:[DB00480 DB07784] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07784|[4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID IGKC common genes common pathways GO:0006955| immune response IGKC;TNFSF11 40523:[DB00480 DB07121] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07121|4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE ADAM17 common genes common pathways GO:0033209| tumor necrosis factor-mediated signaling pathway ADAM17;TNFSF11 GO:0007155| cell adhesion CDH5;ADAM17 GO:0008284| positive regulation of cell proliferation ADAM17;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;ADAM17 GO:0042493| response to drug ADAM17;ABCB1;PTGS2 40524:[DB00480 DB00318] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC22A1 GO:0051260| protein homooligomerization SLC22A1;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0042493| response to drug UGT1A1;PTGS2;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2;CYP3A7;CYP3A5 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2;OPRM1 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0006855| drug transmembrane transport ABCB1;SLC22A1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0006955| immune response OPRD1;OPRK1;TNFSF11 GO:0009314| response to radiation PTGS2;OPRM1;OPRK1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2;UGT2B7 GO:0019233| sensory perception of pain OPRM1;OPRK1;OPRD1;PTGS2 40525:[DB00480 DB01972] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01972|Guanosine-5'-Monophosphate GUK1;pleD;DLG4;GMPR;PDE5A;HINT1;ATIC;purF;TGM3;gpt;purF common genes common pathways GO:0043406| positive regulation of MAP kinase activity PDE5A;TNFSF11 GO:0055085| transmembrane transport DLG4;ABCB1 GO:0055114| oxidation-reduction process PTGS2;GMPR GO:0007612| learning DLG4;PTGS2 40526:[DB00480 DB01217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2C9;CYP3A4 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP19A1;CYP2C9;CYP1A2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 40527:[DB00480 DB05662] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05662|NP-50301 ESR1 common genes common pathways GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;TNFSF11 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 40528:[DB00480 DB02621] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02621|Latrunculin A ACTA1;GSN common genes common pathways GO:0007568| aging PTGS2;GSN GO:0010226| response to lithium ion ACTA1;PTGS2 40529:[DB00480 DB05511] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05511|Piclidenoson ADORA3 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADORA3 GO:0006954| inflammatory response PTGS2;ADORA3 40530:[DB00480 DB06879] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06879|5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE NOS2 common genes common pathways GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 GO:0055114| oxidation-reduction process PTGS2;NOS2 40531:[DB00480 DB07637] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07637|Dibromotyrosine EPOR common genes common pathways GO:0019221| cytokine-mediated signaling pathway TNFSF11;EPOR GO:0046697| decidualization EPOR;PTGS2 40532:[DB00480 DB06791] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0008285| negative regulation of cell proliferation PTGS2;SSTR2;CDH5;SSTR5 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40533:[DB00480 DB03158] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03158|D-Myo-Inositol-1,4-Bisphosphate INPP5B common genes common pathways 40534:[DB00480 DB05202] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05202|Egaptivon pegol VWF;GP1BA common genes common pathways GO:0007155| cell adhesion VWF;CDH5;GP1BA GO:0019221| cytokine-mediated signaling pathway GP1BA;TNFSF11 GO:0051260| protein homooligomerization VWF;TNFSF11 40535:[DB00480 DB01622] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;ADRA1B;ADRA1A;HTR2A GO:0007613| memory HTR2A;DRD1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;ADRA1B;PTGS2 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0007275| multicellular organismal development ADRA1B;TNFSF11 GO:0098869| PTGS2;ALB GO:0007568| aging PTGS2;ADRA1A;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0008284| positive regulation of cell proliferation HTR2A;PTGS2;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0007612| learning PTGS2;DRD1 GO:0042493| response to drug HTR2A;DRD1;DRD2;ADRA1A;PTGS2;ABCB1 40536:[DB00480 DB09286] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;ADRA2A;HTR2B;HTR2A GO:0007612| learning DRD3;PTGS2;DRD1 GO:0043066| negative regulation of apoptotic process HTR2B;PTGS2 GO:0008284| positive regulation of cell proliferation ADRA2A;DRD3;ADRA1D;HTR2A;PTGS2;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0042493| response to drug ABCB1;DRD3;PTGS2;HTR2B;DRD1;HTR2A;DRD2;ADRA1A GO:0007613| memory DRD1;HTR2A;PTGS2 GO:0019722| calcium-mediated signaling HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction ADRA1D;PTGS2;ADRA1B;HTR2A;ADRA1A GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADRA1A;DRD2 GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 40537:[DB00480 DB01062] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP3A5;CYP3A4;CYP2D6 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 40538:[DB00480 DB00693] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00693|Fluorescein CYP1A1;SLC22A6;ABCB11;ABCC1 common genes common pathways GO:0055114| oxidation-reduction process CYP1A1;PTGS2 GO:0042493| response to drug ABCB1;CYP1A1;PTGS2;ABCC1 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCC1;ABCB11;SLC22A6 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0006810| transport ABCB1;ABCC1;ABCB11 GO:0007568| aging CYP1A1;PTGS2 GO:0051260| protein homooligomerization TNFSF11;SLC22A6 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 40539:[DB00480 DB05188] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05188|KD3010 PPARD common genes common pathways GO:0030154| cell differentiation TNFSF11;PPARD GO:0007566| embryo implantation PPARD;PTGS2 GO:0006629| lipid metabolic process PPARD;PTGS2 GO:0010033| response to organic substance PTGS2;PPARD GO:0046697| decidualization PTGS2;PPARD GO:0071456| cellular response to hypoxia PPARD;PTGS2 GO:0050728| negative regulation of inflammatory response PPARD;CDH5 GO:0043066| negative regulation of apoptotic process PPARD;PTGS2 GO:0008284| positive regulation of cell proliferation PPARD;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PPARD 40540:[DB00480 DB06820] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2;CYP2D6;CYP2C9 GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;CYP1A2;PTGS2 40541:[DB00480 DB01320] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0055085| transmembrane transport ABCB1;SCN5A GO:0098869| ALB;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP2D6;CYP2C9;CYP2B6;CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9;CYP2D6;CYP1A2 40542:[DB00480 DB04268] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04268|Methylumbelliferyl Chitotriose LYZ common genes common pathways GO:0006954| inflammatory response LYZ;PTGS2 40543:[DB00480 DB00933] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0019233| sensory perception of pain PTGS2;HTR2A GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2 GO:0007613| memory PTGS2;HTR2A GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0055114| oxidation-reduction process CYP2D6;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;HTR2A;DRD2 GO:0007568| aging PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A 40544:[DB00480 DB13869] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13869|2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol ESR2;ESR1 common genes common pathways GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;TNFSF11 GO:0060749| mammary gland alveolus development TNFSF11;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 40545:[DB00480 DB08143] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08143|5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 40546:[DB00480 DB02820] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02820|1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct HSD17B10 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HSD17B10 GO:0006629| lipid metabolic process PTGS2;HSD17B10 40547:[DB00480 DB02155] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02155|Balanol Analog 8 PRKACA common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle PRKACA;ABCB1 GO:0034605| cellular response to heat PRKACA;PTGS2 40548:[DB00480 DB09498] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09498|Strontium chloride Sr-89 ALPPL2;ALPL;SLC8A1;CACNA1I common genes common pathways GO:0055074| calcium ion homeostasis TNFSF11;SLC8A1 GO:0051384| response to glucocorticoid stimulus ALPL;PTGS2 GO:0033280| response to vitamin D ALPL;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;ALPL GO:0042493| response to drug PTGS2;SLC8A1;ABCB1 GO:0006810| transport CACNA1I;ABCB1 GO:0071456| cellular response to hypoxia PTGS2;SLC8A1 GO:0055085| transmembrane transport CACNA1I;ABCB1;SLC8A1 40549:[DB00480 DB00223] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00223|Diflorasone NR3C1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 40550:[DB00480 DB02432] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02432|RU90395 SRC common genes common pathways GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0070542| response to fatty acid PTGS2;SRC GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0045453| bone resorption SRC;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;SRC GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| SRC;CDH5 GO:1902533| SRC;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway SRC;CDH5 GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 40551:[DB00480 DB02481] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02481|N-Benzylformamide ADH1B common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1B 40552:[DB00480 DB00106] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00106|Abarelix GNRHR common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GNRHR 40553:[DB00480 DB14514] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14514|Magnesium levulinate ATP1A1 common genes common pathways GO:0008217| regulation of blood pressure ATP1A1;PTGS2 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0042493| response to drug ABCB1;ATP1A1;PTGS2 40554:[DB00480 DB04278] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04278|2-[2-(2-Cyclohexyl-2-Guanidino-Acetylamino)-Acetylamino]-N-(3-Mercapto-Propyl)-Propionamide IL2 common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;IL2 GO:0050728| negative regulation of inflammatory response CDH5;IL2 GO:0007155| cell adhesion IL2;CDH5 GO:0043066| negative regulation of apoptotic process PTGS2;IL2 GO:0008284| positive regulation of cell proliferation PTGS2;IL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL2 GO:0006955| immune response TNFSF11;IL2 40555:[DB00480 DB04787] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04787|Tanaproget PGR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;TNFSF11 GO:0038001| paracrine signaling PGR;TNFSF11 40556:[DB00480 DB07001] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07001|(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine NOS3 common genes common pathways GO:0001525| angiogenesis NOS3;PTGS2 GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;NOS3 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process PTGS2;NOS3 40557:[DB00480 DB01116] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01116|Trimethaphan CHRNA10;BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;BCHE GO:0008285| negative regulation of cell proliferation CDH5;BCHE;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;CHRNA10 GO:0007612| learning PTGS2;BCHE GO:0042493| response to drug PTGS2;ABCB1;BCHE 40558:[DB00480 DB00729] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00729|Diphemanil Methylsulfate CHRM3 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 40559:[DB00480 DB09086] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09086|Eugenol ESR1;ESR2;AR;TRPV3 common genes common pathways GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0055085| transmembrane transport ABCB1;TRPV3 GO:0006810| transport ABCB1;AR GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;ESR1;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11;ESR2;ESR1 GO:0008284| positive regulation of cell proliferation AR;PTGS2 40560:[DB00480 DB07675] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07675|(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID PPARG common genes common pathways GO:0042493| response to drug ABCB1;PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0010033| response to organic substance PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0008217| regulation of blood pressure PPARG;PTGS2 40561:[DB00480 DB05038] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05038|Anatibant BDKRB2 common genes common pathways GO:0006954| inflammatory response PTGS2;BDKRB2 GO:1902219| BDKRB2;PTGS2 40562:[DB00480 DB13975] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2C9;CYP2D6;CYP3A4 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP2C9;CYP1A2;CYP3A4 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 40563:[DB00480 DB07250] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07250|N'-(5-CHLORO-1,3-BENZODIOXOL-4-YL)-N-(3,4,5- TRIMETHOXYPHENYL)PYRIMIDINE-2,4-DIAMINE EPHB4 common genes common pathways GO:0007155| cell adhesion EPHB4;CDH5 GO:0007275| multicellular organismal development TNFSF11;EPHB4 GO:0001525| angiogenesis PTGS2;EPHB4 40564:[DB00480 DB06213] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06213|Regadenoson ADORA2A common genes common pathways GO:0051968| positive regulation of synaptic transmission, glutamatergic ADORA2A;PTGS2 GO:0042493| response to drug ABCB1;ADORA2A;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;ADORA2A GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;ADORA2A GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;ADORA2A GO:0006954| inflammatory response PTGS2;ADORA2A 40565:[DB00480 DB09327] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09327|Tegafur-uracil DPYD;TYMS;CYP2A6;DPYD;SLC22A7;SLC29A1;SLC29A2;SLC28A1;SLC28A2;SLC28A3 common genes common pathways GO:0051384| response to glucocorticoid stimulus PTGS2;TYMS GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0034097| response to cytokine stimulus PTGS2;TYMS GO:0042493| response to drug ABCB1;PTGS2;TYMS GO:0055114| oxidation-reduction process PTGS2;CYP2A6;DPYD GO:0071456| cellular response to hypoxia PTGS2;SLC29A1 GO:0007568| aging TYMS;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC22A7 40566:[DB00480 DB00042] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways GO:0030154| cell differentiation SYT2;TNFSF11 40567:[DB00480 DB08386] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08386|2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline PDE10A common genes common pathways 40568:[DB00480 DB00891] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00891|Sulfapyridine CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9 GO:0055114| oxidation-reduction process CYP2C9;PTGS2 40569:[DB00480 DB04655] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04655|Metoprine HNMT common genes common pathways 40570:[DB00480 DB08744] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08744|6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one NQO2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NQO2 40571:[DB00480 DB04253] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04253|Tretazicar NQO2 common genes common pathways GO:0055114| oxidation-reduction process NQO2;PTGS2 40572:[DB00480 DB06314] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06314|SGX-523 MET common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;MET 40573:[DB00480 DB06246] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06246|Exisulind PDE4D;PDE4C;PDE5A;PDE2A;GSTP1;AKR1B1;AKR1B10 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0055114| oxidation-reduction process AKR1B10;AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process GSTP1;PTGS2;AKR1B1 GO:0010033| response to organic substance PTGS2;AKR1B1 GO:0043406| positive regulation of MAP kinase activity PDE5A;TNFSF11 GO:0098869| PTGS2;GSTP1 GO:0032355| response to estradiol stimulus GSTP1;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;PDE4D GO:0007568| aging PTGS2;PDE4D GO:0071260| cellular response to mechanical stimulus PDE2A;PTGS2 40574:[DB00480 DB11811] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11811|Arhalofenate PPARG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0042493| response to drug ABCB1;PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0010033| response to organic substance PPARG;PTGS2 40575:[DB00480 DB05246] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05246|Methsuximide CACNA1G;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2C19 GO:0055085| transmembrane transport CACNA1G;ABCB1 40576:[DB00480 DB06096] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06096|NXN-188 NOS1;HTR1B;HTR1D common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NOS1 GO:0055114| oxidation-reduction process PTGS2;NOS1 GO:0042493| response to drug PTGS2;ABCB1;HTR1B GO:0051926| negative regulation of calcium ion transport PTGS2;NOS1 40577:[DB00480 DB03227] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03227|Nicotinamide Mononucleotide NMNAT1;NMNAT3;BST1;ligA common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;BST1 GO:0050727| regulation of inflammatory response PTGS2;BST1 40578:[DB00480 DB00938] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00938|Salmeterol ADRB2;ADRB1;ADRB3;CYP3A4;CYP3A5;CYP3A7;CYP2C8 common genes common pathways GO:0045453| bone resorption TNFSF11;ADRB2 GO:0050873| brown fat cell differentiation ADRB2;ADRB3;PTGS2;ADRB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0007568| aging ADRB3;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ADRB2 GO:0055114| oxidation-reduction process CYP3A4;CYP2C8;PTGS2;CYP3A5;CYP3A7 GO:0045986| negative regulation of smooth muscle contraction PTGS2;ADRB2 40579:[DB00480 DB07385] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07385|3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE NQO1 common genes common pathways GO:0014070| response to organic cyclic compound NQO1;PTGS2 GO:0006979| response to oxidative stress NQO1;PTGS2 GO:0032355| response to estradiol stimulus NQO1;PTGS2 GO:0007568| aging PTGS2;NQO1 GO:0043066| negative regulation of apoptotic process NQO1;PTGS2 GO:0055114| oxidation-reduction process NQO1;PTGS2 40580:[DB00480 DB00546] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0042493| response to drug PTGS2;GABRG3;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2;CYP2C19 GO:0006810| transport GABRA1;GABRB3;ABCB1;GABRG2;GABRA5;GABRA3;GABRB2;GABRR2;GABRD;GABRB1;GABRR1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40581:[DB00480 DB11254] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11254|Hexylresorcinol TOP1;TGM2;TYR common genes common pathways GO:0051260| protein homooligomerization TNFSF11;TGM2 GO:0055114| oxidation-reduction process TYR;PTGS2 GO:0042493| response to drug ABCB1;TOP1;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TGM2 GO:0033280| response to vitamin D PTGS2;TYR GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TGM2 GO:0043065| positive regulation of apoptotic process TGM2;PTGS2 40582:[DB00480 DB14700] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14700|Damoctocog alfa pegol F8 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;F8 40583:[DB00480 DB01158] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01158|Bretylium ATP1A1 common genes common pathways GO:0071260| cellular response to mechanical stimulus PTGS2;ATP1A1 GO:0008217| regulation of blood pressure PTGS2;ATP1A1 GO:0042493| response to drug PTGS2;ATP1A1;ABCB1 40584:[DB00480 DB02336] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02336|RU83876 SRC common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity SRC;TNFSF11 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| CDH5;SRC GO:1902533| TNFSF11;SRC GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug SRC;PTGS2;ABCB1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process PTGS2;SRC GO:0070542| response to fatty acid PTGS2;SRC GO:0045453| bone resorption SRC;TNFSF11 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC 40585:[DB00480 DB06752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06752|Chymopapain PRG2 common genes common pathways GO:0006955| immune response PRG2;TNFSF11 40586:[DB00480 DB09095] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR3C1 GO:0051384| response to glucocorticoid stimulus ANXA3;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ANXA3 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40587:[DB00480 DB02386] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02386|Leucine Phosphonic Acid LAP3 common genes common pathways 40588:[DB00480 DB13345] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13345|Dihydroergocristine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD1;DRD5;DRD2;DRD3;DRD4;CYP3A4;ABCB11 common genes common pathways GO:0007568| aging PTGS2;ADRB3;ADRA1A;HTR2A GO:0006810| transport ABCB11;ABCB1 GO:0043406| positive regulation of MAP kinase activity HTR2B;HTR2A;ADRA2A;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCB11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;ADRB2;TNFSF11 GO:0008284| positive regulation of cell proliferation ADRA2A;DRD3;ADRA1D;HTR2A;HTR2B;HTR1A;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0007612| learning DRD5;DRD3;DRD1;PTGS2 GO:0045986| negative regulation of smooth muscle contraction ADRB2;PTGS2 GO:0042493| response to drug PTGS2;HTR2B;HTR2A;DRD1;DRD2;ADRA1A;DRD3;ABCB1;HTR1B;HTR2C GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0045453| bone resorption TNFSF11;ADRB2 GO:0045907| positive regulation of vasoconstriction ADRA2C;ADRA1D;HTR2A;ADRA1A;ADRA1B;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0007613| memory DRD1;HTR2A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2;ADRA1B;ADRA1D GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;DRD2;CDH5 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0050873| brown fat cell differentiation ADRB3;ADRB1;PTGS2;ADRB2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;HTR2B GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0070371| ERK1 and ERK2 cascade TNFSF11;HTR2B 40589:[DB00480 DB07903] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07903|3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE METAP1 common genes common pathways 40590:[DB00480 DB06558] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06558|Tezosentan EDNRA;EDNRB common genes common pathways GO:0043066| negative regulation of apoptotic process EDNRB;PTGS2 GO:0008284| positive regulation of cell proliferation EDNRB;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;EDNRB GO:0007568| aging PTGS2;EDNRB GO:0019233| sensory perception of pain EDNRB;PTGS2 GO:0019722| calcium-mediated signaling TNFSF11;EDNRB GO:0008217| regulation of blood pressure EDNRB;EDNRA;PTGS2 GO:0014070| response to organic cyclic compound EDNRB;PTGS2 40591:[DB00480 DB13915] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13915|Axicabtagene ciloleucel CD19 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD19;TNFSF11 40592:[DB00480 DB05793] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05793|PRO-542 FFAR4 common genes common pathways GO:0043066| negative regulation of apoptotic process FFAR4;PTGS2 GO:0050728| negative regulation of inflammatory response CDH5;FFAR4 40593:[DB00480 DB00387] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways GO:0008284| positive regulation of cell proliferation CHRM1;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2;CHRM3 40594:[DB00480 DB11718] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CCND1 GO:0051384| response to glucocorticoid stimulus CCND1;PTGS2 GO:0030154| cell differentiation BRAF;TNFSF11 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;BRAF GO:0033598| mammary gland epithelial cell proliferation CCND1;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;PTGS2 GO:0009887| organ morphogenesis BRAF;TNFSF11 GO:0010033| response to organic substance PTGS2;CCND1 GO:0032355| response to estradiol stimulus PTGS2;CCND1 GO:0042493| response to drug ABCB1;PTGS2;CCND1 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2D6;CYP3A4 GO:0010243| response to organic nitrogen PTGS2;CCND1 GO:0042127| regulation of cell proliferation PTGS2;BRAF GO:0043066| negative regulation of apoptotic process PTGS2;BRAF GO:0008284| positive regulation of cell proliferation PTGS2;CCND1 GO:0060749| mammary gland alveolus development TNFSF11;CCND1 40595:[DB00480 DB05133] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05133|VP025 IL1B common genes common pathways GO:0019221| cytokine-mediated signaling pathway IL1B;TNFSF11 GO:0008284| positive regulation of cell proliferation IL1B;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;TNFSF11 GO:0032496| response to lipopolysaccharide IL1B;PTGS2 GO:0046330| positive regulation of JNK cascade IL1B;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;IL1B GO:0010469| regulation of receptor activity TNFSF11;IL1B GO:0006955| immune response TNFSF11;IL1B GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity IL1B;TNFSF11 GO:0006954| inflammatory response IL1B;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IL1B GO:0071260| cellular response to mechanical stimulus PTGS2;IL1B GO:0010575| positive regulation vascular endothelial growth factor production IL1B;PTGS2 GO:0031622| positive regulation of fever generation IL1B;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade IL1B;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;IL1B;PTGS2 GO:0007566| embryo implantation IL1B;PTGS2 40596:[DB00480 DB00956] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00956|Hydrocodone OPRM1;OPRD1;CYP2D6;CYP3A4 common genes common pathways GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2D6;CYP3A4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0009314| response to radiation OPRM1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0019233| sensory perception of pain PTGS2;OPRD1;OPRM1 GO:0006955| immune response TNFSF11;OPRD1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;OPRM1;CDH5 40597:[DB00480 DB01235] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0007612| learning DRD1;PTGS2;DRD3;DRD5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation PTGS2;DRD3 GO:0042493| response to drug ABCB1;DRD3;PTGS2;DRD1;DRD2 GO:0006810| transport SLC7A8;SLC15A1;SLC7A5;ABCB1 GO:0055085| transmembrane transport SLC15A1;SLC16A10;ABCB1 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007275| multicellular organismal development SLC7A5;TNFSF11 GO:0007613| memory PTGS2;DRD1 GO:0030154| cell differentiation SLC7A5;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 40598:[DB00480 DB03742] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03742|Compound 4-D ESR1 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0050727| regulation of inflammatory response PTGS2;ESR1 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 40599:[DB00480 DB01278] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CALCR;RAMP3;TNFSF11 GO:0032355| response to estradiol stimulus RAMP2;PTGS2 GO:0001525| angiogenesis PTGS2;RAMP2;RAMP1 GO:0010942| positive regulation of cell death PTGS2;RAMP3;CALCR GO:0033138| positive regulation of peptidyl-serine phosphorylation CALCR;RAMP3;PTGS2 GO:0051384| response to glucocorticoid stimulus CALCR;PTGS2 GO:0008217| regulation of blood pressure RAMP2;PTGS2 40600:[DB00480 DB02721] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02721|4-Iodopyrazole ADH1C;ADH1B;ADH1A common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ADH1B;ADH1C;ADH1A 40601:[DB00480 DB01269] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01269|Panitumumab EGFR common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;EGFR GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0014070| response to organic cyclic compound EGFR;PTGS2 GO:0001503| ossification TNFSF11;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;EGFR GO:0006979| response to oxidative stress PTGS2;EGFR GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0032355| response to estradiol stimulus EGFR;PTGS2 GO:0098609| CDH5;EGFR GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0042127| regulation of cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;EGFR GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR 40602:[DB00480 DB05053] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05053|MB-07803 FBP1 common genes common pathways 40603:[DB00480 DB09126] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09126|Chorionic Gonadotropin (Human) LHCGR common genes common pathways GO:0045670| regulation of osteoclast differentiation TNFSF11;LHCGR 40604:[DB00480 DB05369] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05369|HZT-501 HRH2 common genes common pathways GO:0006955| immune response TNFSF11;HRH2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH2 GO:0007613| memory HRH2;PTGS2 40605:[DB00480 DB01348] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport SLC15A2;SLC15A1;ABCB1 GO:0008217| regulation of blood pressure ACE;PTGS2 40606:[DB00480 DB09186] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09186|Nisoxetine SLC6A4 common genes common pathways GO:0042493| response to drug PTGS2;SLC6A4;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A4 GO:0032227| negative regulation of synaptic transmission, dopaminergic SLC6A4;PTGS2 GO:0010033| response to organic substance SLC6A4;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;SLC6A4 GO:0051260| protein homooligomerization TNFSF11;SLC6A4 GO:0007613| memory PTGS2;SLC6A4 40607:[DB00480 DB04703] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04703|Hesperidin AURKB common genes common pathways GO:0034644| cellular response to UV PTGS2;AURKB GO:0007568| aging PTGS2;AURKB 40608:[DB00480 DB06825] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06825|Triptorelin GNRHR common genes common pathways GO:0007275| multicellular organismal development GNRHR;TNFSF11 40609:[DB00480 DB07216] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07216|(11S)-8-CHLORO-11-[1-(METHYLSULFONYL)PIPERIDIN-4-YL]-6-PIPERAZIN-1-YL-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE FNTA;FNTB common genes common pathways GO:0042127| regulation of cell proliferation FNTB;PTGS2 GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;FNTA 40610:[DB00480 DB01941] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01941|6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid RXRB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;RXRB 40611:[DB00480 DB01565] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways GO:0016567| protein ubiquitination CRBN;TRIM13 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;POMC GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CRBN;TRIM13 GO:0010469| regulation of receptor activity TNFSF11;POMC GO:0071456| cellular response to hypoxia PTGS2;OPRD1 GO:0006955| immune response OPRD1;OPRK1;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity TRIM13;TNFSF11 GO:0010942| positive regulation of cell death TRIM13;PTGS2 GO:0009314| response to radiation OPRK1;OPRM1;PTGS2 GO:0019233| sensory perception of pain OPRK1;OPRM1;OPRD1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TRIM13;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0008217| regulation of blood pressure POMC;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 40612:[DB00480 DB14575] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;UGT1A1 GO:0008217| regulation of blood pressure P2RX4;PTGS2 GO:0019722| calcium-mediated signaling P2RX4;TNFSF11 GO:0051384| response to glucocorticoid stimulus PTGS2;UGT1A1 GO:0019233| sensory perception of pain P2RX4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0010033| response to organic substance PTGS2;UGT1A1 GO:0045429| positive regulation of nitric oxide biosynthetic process P2RX4;PTGS2 GO:0051260| protein homooligomerization TNFSF11;P2RX4 GO:0042493| response to drug UGT1A1;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP3A4 GO:0071318| cellular response to ATP P2RX4;PTGS2 GO:0032496| response to lipopolysaccharide UGT1A1;PTGS2 40613:[DB00480 DB01694] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01694|D-tartaric acid B3GAT1;TREM1;DDX6;HIF1AN;serA;lpxA;ATP6V1C1;phnA common genes common pathways GO:0055114| oxidation-reduction process PTGS2;HIF1AN 40614:[DB00480 DB07514] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07514|3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one KDR common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process PTGS2;KDR GO:0030154| cell differentiation KDR;TNFSF11 GO:0001525| angiogenesis KDR;PTGS2 GO:0007275| multicellular organismal development TNFSF11;KDR GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 40615:[DB00480 DB09270] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes ABCB1 common pathways GO:0097756| HMGCR;PTGS2 GO:0006810| transport ABCB1 GO:0007568| aging HMGCR;PTGS2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:1901529| ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HMGCR GO:0043066| negative regulation of apoptotic process PTGS2;HMGCR GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process HMGCR;PTGS2;SDHA;NDUFV3 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0048661| positive regulation of smooth muscle cell proliferation HMGCR;PTGS2 GO:0007613| memory PTGS2;VLDLR GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0006629| lipid metabolic process LDLR;VLDLR;PTGS2;HMGCR 40616:[DB00480 DB12406] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12406|Lisofylline CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process CYP1A2;PTGS2 GO:0042493| response to drug CYP1A2;ABCB1;PTGS2 40617:[DB00480 DB09199] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09199|Netoglitazone CYP3A4;CYP2C8 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP2C8;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40618:[DB00480 DB07393] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07393|2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE GSR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GSR GO:0098869| PTGS2;GSR 40619:[DB00480 DB01839] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01839|Propylene glycol F13A1 common genes common pathways 40620:[DB00480 DB05675] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05675|EP-2104R FGA common genes common pathways GO:0045907| positive regulation of vasoconstriction PTGS2;FGA 40621:[DB00480 DB02262] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02262|Orotic Acid pyrE;DHODH;pyrD;pyrC common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHODH GO:0042493| response to drug PTGS2;DHODH;ABCB1 GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0043065| positive regulation of apoptotic process PTGS2;DHODH 40622:[DB00480 DB03035] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03035|1,8-Di-Hydroxy-4-Nitro-Anthraquinone CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 40623:[DB00480 DB08084] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08084|IDD594 AKR1B1 common genes common pathways GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;AKR1B1 GO:0055114| oxidation-reduction process AKR1B1;PTGS2 GO:0043066| negative regulation of apoptotic process AKR1B1;PTGS2 GO:0010033| response to organic substance AKR1B1;PTGS2 40624:[DB00480 DB03222] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03222|dATP POLB;recA;recA common genes common pathways GO:0006954| inflammatory response POLB;PTGS2 GO:0007568| aging POLB;PTGS2 40625:[DB00480 DB00327] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways GO:0055114| oxidation-reduction process CYP2C9;CYP3A4;PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0006955| immune response OPRD1;OPRK1;TNFSF11 GO:0019233| sensory perception of pain OPRM1;OPRK1;OPRD1;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;CYP2C9;CYP3A4 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation OPRD1;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 40626:[DB00480 DB04776] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04776|(2R)-2-({6-[benzyl(methyl)amino]-9-isopropyl-9H-purin-2-yl}amino)butan-1-ol PDXK common genes common pathways 40627:[DB00480 DB02494] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02494|Alpha-Hydroxy-Beta-Phenyl-Propionic Acid RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13;CPA1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RPL23;TNFSF11 GO:0008284| positive regulation of cell proliferation RPL23;PTGS2 40628:[DB00480 DB07379] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07379|(2S)-2-({6-[(3-amino-5-chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)-3-methylbutan-1-ol CDK6 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;CDK6 GO:0030154| cell differentiation CDK6;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;CDK6 GO:0045786| negative regulation of cell cycle CDK6;PTGS2 40629:[DB00480 DB08601] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08601|tributylstannanyl NCOA2;RXRA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NCOA2;TNFSF11;RXRA GO:0007566| embryo implantation RXRA;PTGS2 40630:[DB00480 DB07645] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07645|SEBACIC ACID HBA1;HBB common genes common pathways GO:0098869| PTGS2;HBA1;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB GO:0010942| positive regulation of cell death HBB;PTGS2;HBA1 GO:0008217| regulation of blood pressure HBB;PTGS2 40631:[DB00480 DB04660] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04660|Choline alfoscerate GM2A common genes common pathways GO:0006629| lipid metabolic process GM2A;PTGS2 40632:[DB00480 DB06494] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06494|Sufugolix GNRHR common genes common pathways GO:0007275| multicellular organismal development TNFSF11;GNRHR 40633:[DB00480 DB07108] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07108|4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID BCL2L1 common genes common pathways GO:0043065| positive regulation of apoptotic process BCL2L1;PTGS2 GO:0009314| response to radiation PTGS2;BCL2L1 GO:0034097| response to cytokine stimulus PTGS2;BCL2L1 GO:0008284| positive regulation of cell proliferation BCL2L1;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;BCL2L1 40634:[DB00480 DB08642] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08642|(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine DHFR common genes common pathways GO:0055114| oxidation-reduction process PTGS2;DHFR 40635:[DB00480 DB09409] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09409|Magnesium acetate tetrahydrate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B common genes common pathways GO:0006810| transport GRIN2C;GRIN2A;GRIN2B;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;GRIN1 GO:0007612| learning GRIN2A;PTGS2;GRIN1 GO:0042493| response to drug ABCB1;GRIN2A;PTGS2 GO:0019722| calcium-mediated signaling GRIN2D;TNFSF11;GRIN2A;GRIN2B;GRIN1;GRIN2C GO:0007613| memory GRIN2A;PTGS2;GRIN1 GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2;GRIN1 GO:0019233| sensory perception of pain PTGS2;GRIN1;GRIN2A GO:0055074| calcium ion homeostasis TNFSF11;GRIN1 40636:[DB00480 DB00048] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00048|Collagenase clostridium histolyticum COL1A1;COL2A1;COL3A1;COL1A2 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;COL3A1;COL1A2 GO:0007568| aging PTGS2;COL3A1 GO:0032355| response to estradiol stimulus PTGS2;COL1A1 GO:0042493| response to drug PTGS2;COL1A1;ABCB1 GO:0034097| response to cytokine stimulus COL3A1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;COL1A2 GO:0071260| cellular response to mechanical stimulus PTGS2;COL1A1 GO:0001503| ossification COL2A1;COL1A1;TNFSF11 GO:0009314| response to radiation COL3A1;PTGS2 40637:[DB00480 DB00102] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00102|Becaplermin PDGFRB;PDGFRA;A2M common genes common pathways GO:0007275| multicellular organismal development PDGFRA;TNFSF11;PDGFRB GO:0043065| positive regulation of apoptotic process PTGS2;PDGFRB GO:0014070| response to organic cyclic compound PDGFRB;PTGS2 GO:0008284| positive regulation of cell proliferation PDGFRA;PTGS2;PDGFRB GO:0043066| negative regulation of apoptotic process PDGFRB;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;PDGFRB GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;PDGFRB;PDGFRA GO:0032355| response to estradiol stimulus PDGFRB;PTGS2 GO:0007568| aging PTGS2;PDGFRB GO:0043406| positive regulation of MAP kinase activity TNFSF11;PDGFRB 40638:[DB00480 DB05239] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05239|Cobimetinib MAP2K1;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes ABCB1 common pathways GO:0070371| ERK1 and ERK2 cascade TNFSF11;MAP2K1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0006855| drug transmembrane transport ABCG2;ABCB1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;MAP2K1 GO:0042908| xenobiotic transport ABCB1;ABCG2 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042493| response to drug ABCB1;PTGS2;ABCG2 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLCO1B1;ABCG2 GO:0006810| transport ABCB1;ABCG2 40639:[DB00480 DB00941] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00941|Hexafluronium BCHE common genes common pathways GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0007612| learning BCHE;PTGS2 GO:0042493| response to drug BCHE;ABCB1;PTGS2 40640:[DB00480 DB02910] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02910|Octanoyl-Coenzyme A ECHS1;ECI1;ACADM common genes common pathways GO:0006631| fatty acid metabolic process PTGS2;ECI1;ACADM;ECHS1 GO:0055114| oxidation-reduction process PTGS2;ACADM GO:0006629| lipid metabolic process ECI1;ECHS1;ACADM;PTGS2 40641:[DB00480 DB02388] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02388|Cyclohexyl-{4-[5-(3,4-Dichlorophenyl)-2-Piperidin-4-Yl-3-Propyl-3h-Imidazol-4-Yl]-Pyrimidin-2-Yl}Amine MAPK10 common genes common pathways 40642:[DB00480 DB02703] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0032496| response to lipopolysaccharide ABCC2;PTGS2;UGT1A1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0042493| response to drug ABCB1;ABCC2;ABCG2;UGT1A1;PTGS2 GO:0006810| transport ABCB11;ABCG2;ABCC2;ABCB1 GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCC2;ABCB11;SLCO1B1;ABCG2 GO:0010033| response to organic substance UGT1A1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 GO:0042908| xenobiotic transport ABCG2;ABCB1 GO:0051384| response to glucocorticoid stimulus UGT1A1;PTGS2 GO:0006855| drug transmembrane transport ABCG2;ABCC2;ABCB1 GO:0014070| response to organic cyclic compound UGT1A1;PTGS2 40643:[DB00480 DB04581] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04581|1-benzylimidazole QPCT common genes common pathways 40644:[DB00480 DB02046] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02046|N-[(Furan-2-Yl)Carbonyl]-(S)-Leucyl-(R)-[1-Amino-2(1h-Indol-3-Yl)Ethyl]-Phosphonic Acid ADAM28 common genes common pathways 40645:[DB00480 DB06264] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06264|Tolperisone CYP1A2 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;PTGS2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0042493| response to drug ABCB1;CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 40646:[DB00480 DB13835] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13835|Caroverine CYP3A4 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40647:[DB00480 DB08378] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08378|4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID MYL6B;MYL12A;MYH7 common genes common pathways 40648:[DB00480 DB01227] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01227|Levacetylmethadol OPRM1;CHRNB4;CHRNA3;CYP3A5;CYP3A7;CYP3A4;CYP19A1 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;OPRM1;PTGS2 GO:0019233| sensory perception of pain PTGS2;OPRM1 GO:0009314| response to radiation OPRM1;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0055114| oxidation-reduction process CYP3A7;CYP3A5;PTGS2;CYP19A1;CYP3A4 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 40649:[DB00480 DB01699] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01699|(4e)-4-Aminohex-4-Enoic Acid ABAT common genes common pathways GO:0007568| aging PTGS2;ABAT GO:0042493| response to drug PTGS2;ABAT;ABCB1 40650:[DB00480 DB00268] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;HTR2B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11;DRD3 GO:0008284| positive regulation of cell proliferation HTR2A;HTR2B;PTGS2;HTR1A;ADRA2A;DRD3 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0007612| learning PTGS2;DRD1;DRD5;DRD3 GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0042493| response to drug DRD3;HTR1B;ABCB1;CYP1A2;HTR2C;PTGS2;HTR2B;HTR2A;DRD1;DRD2 GO:0055114| oxidation-reduction process CYP3A4;CYP1A2;CYP2D6;PTGS2 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0007568| aging HTR2A;PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0043406| positive regulation of MAP kinase activity HTR2A;HTR2B;ADRA2A;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP1A2;CYP3A4 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade HTR2B;TNFSF11 GO:0070371| ERK1 and ERK2 cascade HTR2B;TNFSF11 GO:0045907| positive regulation of vasoconstriction PTGS2;HTR2A;ADRA2C GO:0019722| calcium-mediated signaling TNFSF11;HTR2B GO:0007613| memory PTGS2;DRD1;HTR2A GO:0008285| negative regulation of cell proliferation PTGS2;DRD2;CDH5 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 40651:[DB00480 DB06937] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06937|4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL ESR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR2 40652:[DB00480 DB07800] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07800|N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 40653:[DB00480 DB08169] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08169|(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide DHODH common genes common pathways GO:0042493| response to drug DHODH;PTGS2;ABCB1 GO:0055114| oxidation-reduction process DHODH;PTGS2 GO:0014070| response to organic cyclic compound DHODH;PTGS2 GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 40654:[DB00480 DB11362] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11362|Selexipag PTGIR;CES1;CYP2C8;CYP3A4;SLCO1B1;SLCO1B3;ABCB1 common genes ABCB1 common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1B3;SLCO1B1 GO:0006810| transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP2C8;PTGS2;CYP3A4 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGIR;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40655:[DB00480 DB06263] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0030154| cell differentiation TNFSF11;ABCB5 GO:0042908| xenobiotic transport ABCB1;ABCB5 GO:0006855| drug transmembrane transport ABCB1;ABCB5 GO:0043065| positive regulation of apoptotic process TOP2A;PTGS2 GO:0019371| cyclooxygenase pathway CBR1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;POR GO:0055085| transmembrane transport ABCB5;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TOP2A GO:0043066| negative regulation of apoptotic process POR;PTGS2 GO:0042493| response to drug PTGS2;POR;ABCB1 GO:0055114| oxidation-reduction process POR;CBR1;PTGS2 40656:[DB00480 DB08709] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08709|2,3-diphenyl-1H-indole-7-carboxylic acid PIM1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PIM1 GO:0007275| multicellular organismal development PIM1;TNFSF11 40657:[DB00480 DB03725] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03725|Phosphomethylphosphonic Acid-Guanylate Ester PCK1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PCK1 GO:0032496| response to lipopolysaccharide PCK1;PTGS2 GO:0007568| aging PTGS2;PCK1 GO:0071456| cellular response to hypoxia PTGS2;PCK1 40658:[DB00480 DB06938] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06938|4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide KDR common genes common pathways GO:0001525| angiogenesis KDR;PTGS2 GO:0007275| multicellular organismal development TNFSF11;KDR GO:0070371| ERK1 and ERK2 cascade KDR;TNFSF11 GO:0030154| cell differentiation KDR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;KDR GO:0043066| negative regulation of apoptotic process KDR;PTGS2 40659:[DB00480 DB05710] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways 40660:[DB00480 DB00426] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0055114| oxidation-reduction process CYP3A4;AOX1;PTGS2 40661:[DB00480 DB02740] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02740|3-Indolebutyric Acid tyrB;B2M;TRAC;TRBC1;HLA-A common genes common pathways GO:0042493| response to drug B2M;ABCB1;PTGS2 GO:0006955| immune response TRBC1;B2M;TNFSF11;HLA-A 40662:[DB00480 DB02165] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02165|Zinc Trihydroxide GSTM1 common genes common pathways 40663:[DB00480 DB02824] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02824|N-Pyridoxyl-Glycine-5-Monophosphate glyA;SHMT1;ODC1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;ODC1 GO:1990830| SHMT1;TNFSF11 40664:[DB00480 DB06757] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06757|Manganese IDH3A;IDH3G;TAB1;ARG1;TF;ACO1 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TAB1;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;ARG1 GO:0010042| response to manganese ion PTGS2;ARG1 GO:0042493| response to drug ARG1;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;IDH3G;IDH3A GO:0007568| aging ARG1;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;TAB1 GO:0007179| transforming growth factor beta receptor signaling pathway TAB1;CDH5 40665:[DB00480 DB00753] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0019233| sensory perception of pain CHRNA4;PTGS2;CHRNB2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade ATP2C1;TNFSF11 GO:0007613| memory PTGS2;CHRNB2 GO:0014070| response to organic cyclic compound MT-ND1;PTGS2 GO:0007612| learning PTGS2;CHRNB2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP2B6;MT-ND1 GO:0042493| response to drug ABCB1;MT-ND1;GABRG3;CYP2E1;PTGS2 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0006810| transport GABRB1;GABRA4;GABRA6;GABRD;GABRA5;GABRA3;GABRB2;GABRG2;ABCB1;GABRA1;GABRB3 GO:0006979| response to oxidative stress PTGS2;CHRNA4 GO:0098869| PTGS2;ALB GO:0051260| protein homooligomerization KCNA1;GLRA1;TNFSF11 GO:0055085| transmembrane transport KCNA1;ABCB1;CALM1 40666:[DB00480 DB00121] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00121|Biotin PCCB;HLCS;SLC5A6;MCCC2;ACACB;MCCC1;PC;PCCA;ACACA;CYP1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC5A6 GO:0006810| transport SLC5A6;ABCB1 GO:0055114| oxidation-reduction process CYP1B1;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;ACACB GO:0006631| fatty acid metabolic process ACACA;PTGS2;ACACB GO:0007155| cell adhesion CYP1B1;CDH5 GO:0014070| response to organic cyclic compound ACACB;PTGS2 GO:0008285| negative regulation of cell proliferation CYP1B1;CDH5;PTGS2 GO:0006633| fatty acid biosynthetic process ACACA;PTGS2;ACACB GO:0001525| angiogenesis PTGS2;CYP1B1 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0006629| lipid metabolic process ACACA;PTGS2;ACACB;PC GO:0043065| positive regulation of apoptotic process CYP1B1;PTGS2 40667:[DB00480 DB05432] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05432|DAS-431 IV CALY common genes common pathways 40668:[DB00480 DB01201] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;CYP2C9;CYP2D6;CYP3A4;CYP3A43;CYP2C19;CYP2C8;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP2D6;CYP3A4 40669:[DB00480 DB05389] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05389|Tetrachlorodecaoxide MAEA;CD163 common genes common pathways GO:0007155| cell adhesion CDH5;MAEA GO:0043161| proteasomal ubiquitin-dependent protein catabolic process MAEA;CRBN GO:0006954| inflammatory response PTGS2;CD163 40670:[DB00480 DB04901] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04901|Galiximab CD80 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;CD80 40671:[DB00480 DB06393] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06393|Xaliproden HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2 40672:[DB00480 DB04173] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04173|Fructose FHIT common genes common pathways 40673:[DB00480 DB01117] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;DHODH;MT-CYB GO:0006629| lipid metabolic process PTGS2;CYP3A4;CYP2C9 GO:0043065| positive regulation of apoptotic process PTGS2;DHODH GO:0055114| oxidation-reduction process PTGS2;DHODH;MT-CYB;CYP3A4;CYP2C9 GO:0042493| response to drug PTGS2;DHODH;MT-CYB;ABCB1 GO:0010243| response to organic nitrogen MT-CYB;PTGS2 40674:[DB00480 DB12582] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12582|Piperine NR1I2;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;PTGS2 GO:0042908| xenobiotic transport ABCB1;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 40675:[DB00480 DB04213] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04213|N-Cyclohexyl-N'-(Propyl)Phenyl Urea EPHX2 common genes common pathways GO:0008217| regulation of blood pressure PTGS2;EPHX2 GO:0006629| lipid metabolic process EPHX2;PTGS2 GO:0006954| inflammatory response EPHX2;PTGS2 40676:[DB00480 DB02869] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02869|3-amino-5-phenylpentane CTSV;CTSK common genes common pathways GO:0051384| response to glucocorticoid stimulus CTSV;PTGS2 GO:0045453| bone resorption TNFSF11;CTSK GO:0014070| response to organic cyclic compound CTSV;PTGS2 GO:0046697| decidualization CTSV;PTGS2 40677:[DB00480 DB03722] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03722|3,4-Dihydro-5-Methyl-Isoquinolinone PARP1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;TNFSF11 GO:0007179| transforming growth factor beta receptor signaling pathway PARP1;CDH5 40678:[DB00480 DB07232] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07232|Veliparib PARP1;PARP2 common genes common pathways GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;PARP1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PARP1 40679:[DB00480 DB05855] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05855|Rivanicline CHRNB2;CXCL8 common genes common pathways GO:0001525| angiogenesis CXCL8;PTGS2 GO:0019233| sensory perception of pain CHRNB2;PTGS2 GO:0006954| inflammatory response CXCL8;PTGS2 GO:0006955| immune response TNFSF11;CXCL8 GO:0019722| calcium-mediated signaling TNFSF11;CXCL8 GO:0007613| memory CHRNB2;PTGS2 GO:0008285| negative regulation of cell proliferation CXCL8;CDH5;PTGS2 GO:0007612| learning CHRNB2;PTGS2 GO:0010469| regulation of receptor activity TNFSF11;CXCL8 40680:[DB00480 DB03893] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03893|Thionicotinamide-Adenine-Dinucleotide GAPDH common genes common pathways GO:0055114| oxidation-reduction process PTGS2;GAPDH 40681:[DB00480 DB08262] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08262|2,6-dicarboxynaphthalene HBA1;HBB common genes common pathways GO:0008217| regulation of blood pressure HBB;PTGS2 GO:0010942| positive regulation of cell death HBB;PTGS2;HBA1 GO:0098869| HBA1;PTGS2;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process HBB;PTGS2 40682:[DB00480 DB08745] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08745|4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;TNFSF11 40683:[DB00480 DB01922] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01922|Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam AMY2A;AMY2A common genes common pathways 40684:[DB00480 DB05122] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05122|R1295 ITGA4;ITGB4;ITGB7 common genes common pathways GO:0007155| cell adhesion ITGB7;CDH5;ITGA4;ITGB4 40685:[DB00480 DB02585] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02585|4-(Hydroxymethyl)Benzamidine PRSS3 common genes common pathways 40686:[DB00480 DB04065] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways GO:0055114| oxidation-reduction process ADH1A;PTGS2 40687:[DB00480 DB04720] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04720|S-METHYL-4,5,6,7-TETRABROMO-BENZIMIDAZOLE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process CSNK2A1;PTGS2 40688:[DB00480 DB00844] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;OPRM1 GO:0032496| response to lipopolysaccharide PTGS2;OPRM1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:0019233| sensory perception of pain PTGS2;OPRD1;OPRM1;OPRK1 GO:0009314| response to radiation OPRM1;OPRK1;PTGS2 GO:0006955| immune response OPRD1;TNFSF11;OPRK1 40689:[DB00480 DB07965] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07965|6-(cyclohexylamino)-9-[2-(4-methylpiperazin-1-yl)-ethyl]-9H-purine-2-carbonitrile CTSK common genes common pathways GO:0045453| bone resorption CTSK;TNFSF11 40690:[DB00480 DB08689] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08689|UBIQUINONE-1 SDHA;SDHB;SDHD;SDHC common genes common pathways GO:0055114| oxidation-reduction process SDHA;SDHB;SDHD;PTGS2;SDHC 40691:[DB00480 DB04453] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04453|4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose AMY2A;AMY2A common genes common pathways 40692:[DB00480 DB05079] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05079|HY10275 HRH1;HTR2A common genes common pathways GO:0042493| response to drug PTGS2;HTR2A;ABCB1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0007568| aging PTGS2;HTR2A GO:0006954| inflammatory response PTGS2;HRH1 GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;PTGS2;HRH1 GO:0007613| memory HRH1;HTR2A;PTGS2 40693:[DB00480 DB05403] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05403|CEP-1347 MAPK12 common genes common pathways GO:0045786| negative regulation of cell cycle MAPK12;PTGS2 40694:[DB00480 DB05961] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05961|PPL-100 SERPING1;SERPINA5;SERPINA1 common genes common pathways GO:0007568| aging PTGS2;SERPING1 40695:[DB00480 DB04982] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04982|Talampanel GRIA1;GRIA2;GRIA3;GRIA4 common genes common pathways GO:0006810| transport GRIA4;ABCB1;GRIA3 40696:[DB00480 DB11386] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11386|Chlorobutanol KCNH2 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCB1 40697:[DB00480 DB06021] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06021|AV-412 EGFR;ERBB2 common genes common pathways GO:0014070| response to organic cyclic compound EGFR;PTGS2 GO:0045907| positive regulation of vasoconstriction EGFR;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0001503| ossification TNFSF11;EGFR GO:0071260| cellular response to mechanical stimulus EGFR;PTGS2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR;ERBB2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;EGFR GO:0032355| response to estradiol stimulus PTGS2;EGFR GO:0045780| positive regulation of bone resorption EGFR;TNFSF11 GO:0098609| CDH5;EGFR GO:0006979| response to oxidative stress PTGS2;EGFR GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation EGFR;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;ERBB2;EGFR GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGFR GO:0043066| negative regulation of apoptotic process PTGS2;EGFR 40698:[DB00480 DB04869] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04869|Olcegepant CALCA;CALCRL common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CALCRL GO:0045986| negative regulation of smooth muscle contraction CALCRL;PTGS2 GO:0050728| negative regulation of inflammatory response CALCRL;CDH5 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;CALCRL GO:0010469| regulation of receptor activity TNFSF11;CALCA GO:0001525| angiogenesis PTGS2;CALCRL GO:0008217| regulation of blood pressure PTGS2;CALCA 40699:[DB00480 DB13951] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes ABCB1 common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0006629| lipid metabolic process PTGS2;HSD17B1;CYP11A1 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0006855| drug transmembrane transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP11A1;CYP19A1;CYP17A1;PTGS2;HSD17B1 GO:0099040| ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11;ESR1 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0060749| mammary gland alveolus development TNFSF11;ESR1;AR GO:1901529| ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0006810| transport ABCB1;AR 40700:[DB00480 DB14003] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes ABCB1 common pathways GO:0006810| transport ABCB1;TTPA GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:1901529| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0055114| oxidation-reduction process CYP4F2;PTGS2;CYP3A4 GO:0099040| ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:0007613| memory PTGS2;VLDLR GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:0008217| regulation of blood pressure CYP4F2;PTGS2 GO:0006629| lipid metabolic process CYP3A4;VLDLR;PTGS2;APOBR;TTPA;LDLR 40701:[DB00480 DB09128] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0007568| aging HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0008284| positive regulation of cell proliferation HTR1A;PTGS2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0042493| response to drug DRD2;HTR2A;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4;CYP2D6 GO:0007613| memory HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction HTR2A;ADRA1B;PTGS2;ADRA2C GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;DRD2;PTGS2 GO:0007275| multicellular organismal development TNFSF11;ADRA1B GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP3A4 40702:[DB00480 DB09202] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug ABCB1;PTGS2;ADRA1A GO:0051926| negative regulation of calcium ion transport PTGS2;ADRA2A GO:0008284| positive regulation of cell proliferation PTGS2;ADRA1D;ADRA2A GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0007568| aging ADRA1A;PTGS2 GO:0007275| multicellular organismal development ADRA1D;TNFSF11;ADRA1B GO:0045987| positive regulation of smooth muscle contraction ADRA1D;PTGS2;ADRA1B;ADRA1A GO:0008285| negative regulation of cell proliferation ADRA1A;PTGS2;CDH5 GO:0045907| positive regulation of vasoconstriction ADRA2C;ADRA1D;ADRA1A;PTGS2;ADRA1B 40703:[DB00480 DB09161] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09161|Technetium Tc-99m sestamibi ABCB1;ABCC1 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug PTGS2;ABCC1;ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:1901529| ABCB1 40704:[DB00480 DB00141] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00141|N-Acetylglucosamine B4GALT3;B4GALT4;B4GALT2;NAGK;NAGPA;NAGLU;RENBP;B4GALT1 common genes common pathways GO:0007613| memory B4GALT2;PTGS2 GO:0008217| regulation of blood pressure RENBP;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;B4GALT1;CDH5 GO:0043065| positive regulation of apoptotic process PTGS2;B4GALT1 GO:0051260| protein homooligomerization TNFSF11;B4GALT1 GO:0042127| regulation of cell proliferation B4GALT1;PTGS2 GO:0007155| cell adhesion CDH5;B4GALT1 40705:[DB00480 DB03904] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03904|Urea ARG1;CA2;CTNNB1;SLC14A2;SLC14A1 common genes common pathways GO:0010042| response to manganese ion PTGS2;ARG1 GO:0042493| response to drug PTGS2;ARG1;CTNNB1;ABCB1 GO:0030316| osteoclast differentiation TNFSF11;CTNNB1 GO:0034332| adherens junction organization CTNNB1;CDH5 GO:2001225| regulation of chloride transport ABCB1;CA2 GO:0008284| positive regulation of cell proliferation CTNNB1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CTNNB1;TNFSF11 GO:0007155| cell adhesion CDH5;CTNNB1 GO:0032496| response to lipopolysaccharide PTGS2;ARG1 GO:0042127| regulation of cell proliferation CTNNB1;PTGS2 GO:0010033| response to organic substance CA2;PTGS2 GO:0055085| transmembrane transport SLC14A1;ABCB1;SLC14A2 GO:0043161| proteasomal ubiquitin-dependent protein catabolic process CTNNB1;CRBN GO:0032355| response to estradiol stimulus PTGS2;CTNNB1 GO:0045780| positive regulation of bone resorption CA2;TNFSF11 GO:0045670| regulation of osteoclast differentiation TNFSF11;CTNNB1 GO:0098609| CDH5;CTNNB1 GO:0007568| aging PTGS2;ARG1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;CTNNB1 GO:0071498| cellular response to fluid shear stress CA2;PTGS2 GO:0045672| positive regulation of osteoclast differentiation CA2;TNFSF11 GO:0043065| positive regulation of apoptotic process CTNNB1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade CTNNB1;TNFSF11 GO:0008285| negative regulation of cell proliferation CTNNB1;PTGS2;CDH5 GO:0045453| bone resorption CTNNB1;TNFSF11 GO:0030154| cell differentiation CTNNB1;TNFSF11 40706:[DB00480 DB07177] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0055114| oxidation-reduction process PTGR1;PTGS2;PTGR2 GO:0006693| prostaglandin metabolic process PTGR1;PTGS2;PTGR2 40707:[DB00480 DB03793] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process PTGS2;SLC16A1 GO:0006954| inflammatory response PTGS2;PRDX5 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;PRDX5 GO:0043066| negative regulation of apoptotic process PRDX5;PTGS2 GO:0055114| oxidation-reduction process PRDX5;PTGS2;DAO GO:0006979| response to oxidative stress PTGS2;PRDX5 GO:0098869| PRDX5;PTGS2 GO:0006810| transport SLC15A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC16A1;SLCO2B1;SLC22A8 40708:[DB00480 DB08232] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08232|[5-(5-Amino-1H-pyrrolo[3,2-b]pyridin-2-yl)-6-hydroxy-3'-nitro-3-biphenylyl]acetic acid F7;F3 common genes common pathways GO:0014070| response to organic cyclic compound F7;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;F7 GO:0051897| positive regulation of protein kinase B signaling cascade F7;TNFSF11;F3 GO:0019221| cytokine-mediated signaling pathway TNFSF11;F3 40709:[DB00480 DB02731] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02731|Ethylmercurithiosalicylic acid OXCT1 common genes common pathways GO:0042493| response to drug OXCT1;PTGS2;ABCB1 40710:[DB00480 DB07984] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07984|2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide PTGS1 common genes common pathways GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0055114| oxidation-reduction process PTGS2;PTGS1 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 40711:[DB00480 DB13892] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13892|Crotalus atrox antivenin PLA2G10;CYP4A11 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G10 GO:0055114| oxidation-reduction process PTGS2;CYP4A11 GO:0006631| fatty acid metabolic process CYP4A11;PTGS2 GO:1990830| TNFSF11;PLA2G10 40712:[DB00480 DB06480] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes ABCB1 common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;ALB GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:0006810| transport ABCB1 GO:0098869| ALB;PTGS2 GO:0055085| transmembrane transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 40713:[DB00480 DB07983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07983|1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID PTGS1 common genes common pathways GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS1;PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0098869| PTGS1;PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;PTGS1 40714:[DB00480 DB01616] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01616|Alverine HTR1A common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A 40715:[DB00480 DB07769] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07769|S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0006810| transport AR;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;AR GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR 40716:[DB00480 DB00881] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0008217| regulation of blood pressure PTGS2;ACE GO:0006810| transport ABCB1;SLC15A1;SLC15A2 GO:0055085| transmembrane transport ABCB1;SLC15A1;SLC15A2;SLC22A8 40717:[DB00480 DB07454] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07454|(R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE AR common genes common pathways GO:0006810| transport AR;ABCB1 GO:0060749| mammary gland alveolus development TNFSF11;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0008285| negative regulation of cell proliferation PTGS2;AR;CDH5 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 40718:[DB00480 DB08489] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08489|N4-HYDROXY-2-ISOBUTYL-N1-(9-OXO-1,8-DIAZA-TRICYCLO[10.6.1.013,18]NONADECA-12(19),13,15,17-TETRAEN-10-YL)-SUCCINAMIDE MMP7 common genes common pathways GO:0007568| aging MMP7;PTGS2 GO:0071260| cellular response to mechanical stimulus MMP7;PTGS2 40719:[DB00480 DB09117] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09117|Paraldehyde ALDH2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;ALDH2 40720:[DB00480 DB00170] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0014070| response to organic cyclic compound CYP1A2;F7;NQO1;CYP1A1;PTGS2 GO:1903142| PROC;CDH5 GO:0007275| multicellular organismal development F2;TNFSF11 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0010033| response to organic substance CYP1A2;CYP1A1;PTGS2 GO:0010469| regulation of receptor activity F2;TNFSF11 GO:0032355| response to estradiol stimulus F7;NQO1;CYP1A2;PTGS2 GO:0007568| aging CYP1A1;PTGS2;NQO1 GO:0006979| response to oxidative stress PTGS2;NQO1 GO:0042493| response to drug CYP1A2;MTHFR;ABCB1;CYP2E1;CYP1A1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AOX1;CYP2E1;XDH;VKORC1L1;CYP1A1;CYP2A6;VKORC1;NQO1;NQO2;CYP1A2;MTHFR GO:0050728| negative regulation of inflammatory response CDH5;PROC GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F7;F10 GO:0032496| response to lipopolysaccharide CYP1A1;PTGS2;CYP1A2 GO:0008284| positive regulation of cell proliferation PTGS2;F2 GO:0043066| negative regulation of apoptotic process PTGS2;PROC;NQO1 40721:[DB00480 DB06403] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes ABCB1 common pathways GO:0019233| sensory perception of pain EDNRB;PTGS2 GO:0006629| lipid metabolic process PTGS2;UGT2B7;CYP3A4 GO:0006855| drug transmembrane transport ABCB1 GO:0014070| response to organic cyclic compound EDNRB;PTGS2 GO:0008217| regulation of blood pressure EDNRB;EDNRA;PTGS2 GO:0042908| xenobiotic transport ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0019722| calcium-mediated signaling TNFSF11;EDNRB GO:0072089| stem cell proliferation ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A5;PTGS2;CYP2C19;CYP3A4 GO:0042493| response to drug ABCB1;PTGS2 GO:0032496| response to lipopolysaccharide PTGS2;EDNRB GO:1901529| ABCB1 GO:0043066| negative regulation of apoptotic process PTGS2;EDNRB GO:0008284| positive regulation of cell proliferation PTGS2;EDNRB GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0006810| transport ABCB1 GO:0007568| aging PTGS2;EDNRB 40722:[DB00480 DB08577] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08577|3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE FGFR1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;FGFR1 GO:0042127| regulation of cell proliferation FGFR1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;FGFR1 GO:0043406| positive regulation of MAP kinase activity FGFR1;TNFSF11 GO:0001525| angiogenesis PTGS2;FGFR1 40723:[DB00480 DB07347] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07347|4-(2-Aminoethyl)Benzenesulfonyl Fluoride GAPDH;ATP6V1B2 common genes common pathways GO:0055114| oxidation-reduction process GAPDH;PTGS2 40724:[DB00480 DB01339] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01339|Vecuronium CHRNA2;ABCB1 common genes ABCB1 common pathways GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0006855| drug transmembrane transport ABCB1 GO:1901529| ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0006810| transport ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 40725:[DB00480 DB03891] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03891|1,5-Bis(N-Benzyloxycarbonyl-L-Leucinyl)Carbohydrazide CTSK common genes common pathways GO:0045453| bone resorption TNFSF11;CTSK 40726:[DB00480 DB05214] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05214|KD7040 NOS2 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;NOS2 GO:0032496| response to lipopolysaccharide PTGS2;NOS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 40727:[DB00480 DB03468] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03468|1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide PNMT common genes common pathways 40728:[DB00480 DB13857] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PGR GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0038001| paracrine signaling PGR;TNFSF11 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40729:[DB00480 DB00587] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00587|Cinalukast CYSLTR1 common genes common pathways 40730:[DB00480 DB05939] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05939|MK-0354 GPER1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;GPER1 GO:0008284| positive regulation of cell proliferation PTGS2;GPER1 GO:0050728| negative regulation of inflammatory response CDH5;GPER1 GO:0043065| positive regulation of apoptotic process GPER1;PTGS2 GO:0006954| inflammatory response PTGS2;GPER1 GO:0030154| cell differentiation TNFSF11;GPER1 GO:0008285| negative regulation of cell proliferation PTGS2;GPER1;CDH5 40731:[DB00480 DB00272] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00272|Betazole HRH2 common genes common pathways GO:0007613| memory HRH2;PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2;HRH2 GO:0006955| immune response HRH2;TNFSF11 40732:[DB00480 DB00952] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;HTR1A GO:0042493| response to drug PTGS2;ABCB1;HTR1B GO:0055114| oxidation-reduction process PTGS2;MAOA 40733:[DB00480 DB12662] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12662|Naveglitazar PPARG common genes common pathways GO:0010033| response to organic substance PTGS2;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;PPARG GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0008285| negative regulation of cell proliferation PPARG;CDH5;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity PPARG;TNFSF11 40734:[DB00480 DB03179] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03179|Sinapoyl Coenzyme A COMTD1 common genes common pathways 40735:[DB00480 DB00019] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00019|Pegfilgrastim CSF3R;ELANE common genes common pathways GO:0019221| cytokine-mediated signaling pathway CSF3R;TNFSF11 GO:0050728| negative regulation of inflammatory response ELANE;CDH5 GO:0048661| positive regulation of smooth muscle cell proliferation ELANE;PTGS2 GO:0007155| cell adhesion CDH5;CSF3R GO:0032496| response to lipopolysaccharide PTGS2;ELANE GO:0043406| positive regulation of MAP kinase activity TNFSF11;ELANE 40736:[DB00480 DB13615] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13615|Mifamurtide TLR4;NOD2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOD2;TNFSF11;TLR4 GO:0008284| positive regulation of cell proliferation PTGS2;NOD2 GO:0032496| response to lipopolysaccharide TLR4;PTGS2 GO:0046330| positive regulation of JNK cascade TNFSF11;NOD2;TLR4 GO:0043406| positive regulation of MAP kinase activity NOD2;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process TLR4;PTGS2 GO:0006955| immune response TLR4;TNFSF11 GO:0006954| inflammatory response PTGS2;TLR4 GO:0051092| positive regulation of NF-kappaB transcription factor activity NOD2;TNFSF11;TLR4 GO:0050727| regulation of inflammatory response NOD2;PTGS2;TLR4 GO:0071260| cellular response to mechanical stimulus TLR4;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TLR4;NOD2;TNFSF11 40737:[DB00480 DB09147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09147|Ferric pyrophosphate FTL;HBA1;HBB common genes common pathways GO:0008217| regulation of blood pressure HBB;PTGS2 GO:0010942| positive regulation of cell death HBB;HBA1;PTGS2 GO:0098869| HBA1;PTGS2;HBB GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;HBB 40738:[DB00480 DB00109] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00109|Enfuvirtide CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug ABCB1;CYP2E1;PTGS2 GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP2C19 GO:0010243| response to organic nitrogen CYP2E1;PTGS2 40739:[DB00480 DB02371] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02371|2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid C1S common genes common pathways 40740:[DB00480 DB02028] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02028|(1R,2R,3S,4R,6S)-3,4,6-Trihydroxy-5-{[(S)-hydroxy(3-hydroxy-2-oxopropoxy)phosphoryl]oxy}-1,2-cyclohexanediyl bis[dihydrogen (phosphate)] TUB common genes common pathways 40741:[DB00480 DB07209] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07209|(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid PPARG common genes common pathways GO:0043065| positive regulation of apoptotic process PPARG;PTGS2 GO:0006629| lipid metabolic process PPARG;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;PPARG;CDH5 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0042493| response to drug PPARG;ABCB1;PTGS2 GO:0010033| response to organic substance PTGS2;PPARG 40742:[DB00480 DB08583] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08583|2-amino-5-[3-(1-ethyl-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethylbenzamide ABL1 common genes common pathways GO:0006979| response to oxidative stress PTGS2;ABL1 GO:0042127| regulation of cell proliferation PTGS2;ABL1 GO:0007155| cell adhesion ABL1;CDH5 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis ABL1;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;ABL1 GO:0043065| positive regulation of apoptotic process ABL1;PTGS2 40743:[DB00480 DB00646] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00646|Nystatin CYP3A4;SLCO1B1;SLCO1B3 common genes common pathways GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0055085| transmembrane transport SLCO1B1;SLCO1B3;ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 40744:[DB00480 DB00222] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0007613| memory ABCC8;PTGS2 GO:0006629| lipid metabolic process CYP2C9;PTGS2 GO:0055085| transmembrane transport ABCB1;ABCC8;KCNJ11;ABCB11 GO:0006810| transport ABCB1;ABCB11 GO:0032355| response to estradiol stimulus PTGS2;KCNJ11 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0042493| response to drug ABCB1;PTGS2;ABCC8;KCNJ11 GO:0032496| response to lipopolysaccharide ABCC8;PTGS2 40745:[DB00480 DB08462] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08462|N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE SRC common genes common pathways GO:0042127| regulation of cell proliferation SRC;PTGS2 GO:0007155| cell adhesion CDH5;SRC GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0034332| adherens junction organization SRC;CDH5 GO:0042493| response to drug ABCB1;PTGS2;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| CDH5;SRC GO:1902533| TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0043065| positive regulation of apoptotic process SRC;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process SRC;PTGS2 GO:0071498| cellular response to fluid shear stress SRC;PTGS2 GO:0070542| response to fatty acid SRC;PTGS2 GO:0032463| negative regulation of protein homooligomerization SRC;CRBN GO:0045453| bone resorption SRC;TNFSF11 40746:[DB00480 DB00721] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0019233| sensory perception of pain PTGS2;SCN10A GO:0043065| positive regulation of apoptotic process KCNMA1;PTGS2 GO:0045332| phospholipid translocation KCNN4;ABCB1 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;SLC6A3 GO:0008285| negative regulation of cell proliferation BCHE;CDH5;PTGS2 GO:0007612| learning BCHE;PTGS2 GO:0032496| response to lipopolysaccharide MAOB;PTGS2 GO:0055114| oxidation-reduction process MAOB;MAOA;PTGS2 GO:0042493| response to drug ABCB1;BCHE;PTGS2;SLC6A3;MAOB GO:0007568| aging KCNMB1;PTGS2;SLC6A3 GO:0071456| cellular response to hypoxia KCNMB1;PTGS2 GO:0055085| transmembrane transport SCN10A;SLC6A3;KCNMA1;ABCB1 40747:[DB00480 DB03932] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03932|LFA703 ITGAL common genes common pathways GO:0006954| inflammatory response ITGAL;PTGS2 GO:0098609| ITGAL;CDH5 GO:0007155| cell adhesion ITGAL;CDH5 40748:[DB00480 DB01195] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2C9;CYP2D6 GO:0055114| oxidation-reduction process PTGS2;CYP2C9;CYP2D6 GO:0055085| transmembrane transport SCN4A;SCN5A;ABCB1;KCNH2 40749:[DB00480 DB11071] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes PTGS2 common pathways GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0007566| embryo implantation PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:1990776| PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:0009314| response to radiation PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2;PTGS1 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0046697| decidualization PTGS2 GO:0030282| bone mineralization PTGS2 GO:0007568| aging PTGS2 GO:0097756| PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0034605| cellular response to heat PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0010033| response to organic substance PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0042127| regulation of cell proliferation PTGS1;PTGS2 GO:0007612| learning PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0006631| fatty acid metabolic process PTGS2;PTGS1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCB1;PTGS2 40750:[DB00480 DB08191] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08191|4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid SGK1 common genes common pathways GO:0008217| regulation of blood pressure PTGS2;SGK1 GO:0042127| regulation of cell proliferation SGK1;PTGS2 40751:[DB00480 DB13257] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13257|Ferrous sulfate anhydrous NDUFS8;SDHA;XDH;ACO2;CYP4A11;SUOX;MPO;CAT;NOS2;PTGS1;PTGS2;TPH1;P4HA1;RRM1;PCBD1;TMLHE;CP;TF;FTL;FTH1;fbpA common genes PTGS2 common pathways GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0019233| sensory perception of pain PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0001525| angiogenesis PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2;CAT GO:0006629| lipid metabolic process PTGS2;PTGS1 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS1;PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0006955| immune response TNFSF11;FTH1 GO:0051092| positive regulation of NF-kappaB transcription factor activity CAT;TNFSF11 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS1;PTGS2 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0070542| response to fatty acid CAT;PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS1;PTGS2 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0008285| negative regulation of cell proliferation FTH1;PTGS2;CDH5 GO:0008217| regulation of blood pressure PTGS1;PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2;PTGS1 GO:0032496| response to lipopolysaccharide NOS2;PTGS2;MPO GO:0071284| cellular response to lead ion PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;MPO;CAT GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034097| response to cytokine stimulus PTGS2 GO:0060749| mammary gland alveolus development TNFSF11;TPH1 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0006631| fatty acid metabolic process CYP4A11;PTGS1;PTGS2 GO:0042493| response to drug CAT;ABCB1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;NOS2;XDH;CYP4A11;FTH1;MPO;PTGS1;NDUFS8;P4HA1;SDHA;TMLHE;CP;PCBD1;CAT;RRM1;TPH1;SUOX GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0034605| cellular response to heat PTGS2 GO:0032355| response to estradiol stimulus CAT;PTGS2 GO:1902219| PTGS2 GO:0007568| aging MPO;PTGS2;CAT GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0006979| response to oxidative stress NDUFS8;PTGS1;MPO;PTGS2;CAT GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| CAT;PTGS1;PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 40752:[DB00480 DB05232] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways GO:0055085| transmembrane transport ABCB1;SCN2A;SCN8A;SCN3A;SCN1A 40753:[DB00480 DB03851] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03851|Carbazole Butanoic Acid FABP4 common genes common pathways GO:0050727| regulation of inflammatory response FABP4;PTGS2 GO:0050873| brown fat cell differentiation PTGS2;FABP4 40754:[DB00480 DB08478] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08478|N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide TYMS common genes common pathways GO:0014070| response to organic cyclic compound TYMS;PTGS2 GO:0051384| response to glucocorticoid stimulus TYMS;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;TYMS GO:0034097| response to cytokine stimulus TYMS;PTGS2 GO:0007568| aging TYMS;PTGS2 40755:[DB00480 DB05950] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05950|Contulakin-G CACNA1B common genes common pathways GO:0008217| regulation of blood pressure PTGS2;CACNA1B GO:0055085| transmembrane transport CACNA1B;ABCB1 GO:0006810| transport CACNA1B;ABCB1 40756:[DB00480 DB07112] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07112|N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE EGLN1 common genes common pathways GO:0055114| oxidation-reduction process EGLN1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;EGLN1 40757:[DB00480 DB01827] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01827|2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide LGALS3 common genes common pathways GO:0002548| monocyte chemotaxis LGALS3;TNFSF11 GO:0030154| cell differentiation TNFSF11;LGALS3 40758:[DB00480 DB00996] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0043065| positive regulation of apoptotic process GRIN2A;PTGS2;GRIN1 GO:0019233| sensory perception of pain GRIN1;PTGS2;GRIN2A GO:0006954| inflammatory response PTGS2;ADORA1 GO:0055074| calcium ion homeostasis GRIN1;TNFSF11 GO:0007613| memory GRIN2A;GRIN1;PTGS2 GO:0019722| calcium-mediated signaling GRIN2C;GRIN1;GRIN2B;GRIN2A;TNFSF11;GRIN2D GO:0008217| regulation of blood pressure CACNA1B;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;ADORA1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;TNFSF11 GO:0043066| negative regulation of apoptotic process PTGS2;ADORA1 GO:0007612| learning PTGS2;GRIN1;GRIN2A GO:0050728| negative regulation of inflammatory response CDH5;ADORA1 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 GO:0042493| response to drug PTGS2;ABCB1;GRIN2A GO:0097756| ADORA1;PTGS2 GO:0006810| transport GRIN2C;CACNA1B;ABCB1;GRIN2A;GRIN2B GO:0055085| transmembrane transport CACNA1B;ABCB1 40759:[DB00480 DB11219] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11219|Enzacamene PGR;AR;ESR2;ESR1 common genes common pathways GO:0006810| transport ABCB1;AR GO:0032355| response to estradiol stimulus ESR1;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2;ESR1 GO:0060749| mammary gland alveolus development AR;TNFSF11;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2;ESR1;AR;PGR GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;AR GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1;ESR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0038001| paracrine signaling PGR;TNFSF11 GO:0042327| positive regulation of phosphorylation AR;TNFSF11 GO:0050727| regulation of inflammatory response PTGS2;ESR1 40760:[DB00480 DB03732] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03732|Etheno-Nadp BST1 common genes common pathways GO:0050727| regulation of inflammatory response BST1;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;BST1 40761:[DB00480 DB05183] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05183|MLN0415 IKBKB common genes common pathways GO:0033209| tumor necrosis factor-mediated signaling pathway IKBKB;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKB;TNFSF11 GO:0043066| negative regulation of apoptotic process IKBKB;PTGS2 GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;IKBKB GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;IKBKB GO:0006954| inflammatory response PTGS2;IKBKB 40762:[DB00480 DB03382] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03382|S-oxy-L-cysteine panD;PREP;SOD1 common genes common pathways GO:0055114| oxidation-reduction process SOD1;PTGS2 GO:0042493| response to drug PTGS2;SOD1;ABCB1 GO:0043066| negative regulation of apoptotic process SOD1;PTGS2 GO:0071318| cellular response to ATP PTGS2;SOD1 GO:0010033| response to organic substance SOD1;PTGS2 GO:0006979| response to oxidative stress PTGS2;SOD1 GO:0007568| aging PTGS2;SOD1 GO:0043065| positive regulation of apoptotic process SOD1;PTGS2 GO:0008217| regulation of blood pressure SOD1;PTGS2 GO:0007566| embryo implantation PTGS2;SOD1 40763:[DB00480 DB08790] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08790|1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID HPGDS common genes common pathways GO:0006693| prostaglandin metabolic process PTGS2;HPGDS GO:0006629| lipid metabolic process HPGDS;PTGS2 GO:0019371| cyclooxygenase pathway HPGDS;PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS GO:0006631| fatty acid metabolic process HPGDS;PTGS2 40764:[DB00480 DB07940] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07940|9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCB1;PTGS2 GO:0007612| learning PTGS2;BCHE GO:0008285| negative regulation of cell proliferation PTGS2;BCHE;CDH5 GO:0051384| response to glucocorticoid stimulus BCHE;PTGS2 40765:[DB00480 DB03935] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03935|1,4-Dideoxy-O2-Sulfo-Glucuronic Acid FGF2;ANXA5 common genes common pathways GO:0001525| angiogenesis FGF2;PTGS2 GO:0007275| multicellular organismal development TNFSF11;FGF2 GO:0030154| cell differentiation FGF2;TNFSF11 GO:0072089| stem cell proliferation FGF2;ABCB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;FGF2 GO:0008284| positive regulation of cell proliferation FGF2;PTGS2 GO:0043066| negative regulation of apoptotic process ANXA5;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade FGF2;TNFSF11 GO:0010469| regulation of receptor activity FGF2;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;FGF2 GO:0010033| response to organic substance PTGS2;ANXA5 GO:0009887| organ morphogenesis TNFSF11;FGF2 40766:[DB00480 DB01746] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01746|D-Leucine SLC16A10;SLC7A5 common genes common pathways GO:0007275| multicellular organismal development SLC7A5;TNFSF11 GO:0030154| cell differentiation TNFSF11;SLC7A5 GO:0006810| transport SLC7A5;ABCB1 GO:0055085| transmembrane transport SLC16A10;ABCB1 40767:[DB00480 DB06207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB4;ABCB1 GO:0014070| response to organic cyclic compound ABCB4;PTGS2 GO:0033280| response to vitamin D ABCB4;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;ADRA1A;PTGS2 GO:0045987| positive regulation of smooth muscle contraction ADRA1D;ADRA1B;PTGS2;ADRA1A GO:0042908| xenobiotic transport ABCB4;ABCB1 GO:0035633| maintenance of blood-brain barrier ABCB4;PTGS2 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCB4 GO:0072089| stem cell proliferation ABCB1 GO:0045907| positive regulation of vasoconstriction ADRA1D;PTGS2;ADRA1B;ADRA1A GO:0007275| multicellular organismal development ADRA1B;ADRA1D;TNFSF11 GO:0006629| lipid metabolic process PTGS2;UGT2B7;ABCB4;CYP3A4 GO:0055085| transmembrane transport ABCB4;ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance PTGS2;ABCB4 GO:0006810| transport ABCB4;ABCB1 GO:0007568| aging PTGS2;ADRA1A GO:0032355| response to estradiol stimulus PTGS2;ABCB4 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB4;ABCB1 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0042493| response to drug PTGS2;ADRA1A;ABCB4;ABCB1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide PTGS2;ABCB4 GO:0008284| positive regulation of cell proliferation ADRA1D;PTGS2 40768:[DB00480 DB08052] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08052|1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine SRC common genes common pathways GO:0070542| response to fatty acid SRC;PTGS2 GO:0045453| bone resorption TNFSF11;SRC GO:0032463| negative regulation of protein homooligomerization CRBN;SRC GO:0071498| cellular response to fluid shear stress PTGS2;SRC GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;SRC GO:0043065| positive regulation of apoptotic process PTGS2;SRC GO:0043406| positive regulation of MAP kinase activity TNFSF11;SRC GO:0007179| transforming growth factor beta receptor signaling pathway CDH5;SRC GO:1902533| SRC;TNFSF11 GO:0071456| cellular response to hypoxia SRC;PTGS2 GO:0098609| CDH5;SRC GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;SRC GO:0034332| adherens junction organization CDH5;SRC GO:0042493| response to drug ABCB1;SRC;PTGS2 GO:0007155| cell adhesion SRC;CDH5 GO:0043066| negative regulation of apoptotic process SRC;PTGS2 GO:0042127| regulation of cell proliferation SRC;PTGS2 40769:[DB00480 DB09031] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09031|Miltefosine ABCB1;PLD1 common genes ABCB1 common pathways GO:0006629| lipid metabolic process PLD1;PTGS2 GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0099040| ABCB1 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug PTGS2;ABCB1 GO:1901529| ABCB1 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0006810| transport ABCB1 40770:[DB00480 DB08429] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08429|N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide DPP4 common genes common pathways GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 GO:0007155| cell adhesion CDH5;DPP4 40771:[DB00480 DB02217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02217|Dpb-T NT5M common genes common pathways 40772:[DB00480 DB01406] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR1;TNFSF11 GO:0006955| immune response CCL2;TNFSF11 GO:0006954| inflammatory response CCL2;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity AR;TNFSF11 GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0038001| paracrine signaling TNFSF11;PGR GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0007275| multicellular organismal development TNFSF11;GNRHR GO:0001525| angiogenesis CCL2;PTGS2 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0050870| positive regulation of T cell activation CCL2;TNFSF11 GO:0019221| cytokine-mediated signaling pathway CCL2;TNFSF11 GO:0055114| oxidation-reduction process PTGS2;CYP19A1;CYP3A4 GO:0002548| monocyte chemotaxis CCL2;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;AR;PGR GO:0060749| mammary gland alveolus development ESR1;TNFSF11;AR GO:0007155| cell adhesion CCL2;CDH5 GO:0009887| organ morphogenesis CCL2;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0010469| regulation of receptor activity CCL2;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;ESR1 GO:0006810| transport AR;ABCB1 40773:[DB00480 DB09552] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB09552|Thonzonium ATP6V1C1 common genes common pathways 40774:[DB00480 DB03480] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03480|Brequinar Analog DHODH common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;DHODH GO:0043065| positive regulation of apoptotic process DHODH;PTGS2 GO:0055114| oxidation-reduction process PTGS2;DHODH GO:0042493| response to drug DHODH;PTGS2;ABCB1 40775:[DB00480 DB04531] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04531|Benzylcysteine MGMT common genes common pathways GO:0014070| response to organic cyclic compound MGMT;PTGS2 GO:0042493| response to drug ABCB1;MGMT;PTGS2 GO:0043066| negative regulation of apoptotic process MGMT;PTGS2 40776:[DB00480 DB06708] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP3A4;CYP2D6;PTGS2 GO:0006629| lipid metabolic process CYP2D6;CYP3A4;PTGS2 40777:[DB00480 DB01625] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01625|Isopropamide CHRM3;CHRM4 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction CHRM3;PTGS2 40778:[DB00480 DB05035] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05035|Eprotirome THRA;THRB common genes common pathways GO:0009887| organ morphogenesis TNFSF11;THRB;THRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;THRB;TNFSF11 GO:0001503| ossification THRA;TNFSF11 40779:[DB00480 DB03782] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03782|N-(1-Adamantyl)-N'-(4-Guanidinobenzyl)Urea PLAU common genes common pathways GO:0042127| regulation of cell proliferation PTGS2;PLAU GO:0010469| regulation of receptor activity PLAU;TNFSF11 40780:[DB00480 DB06729] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06729|Sulfaphenazole CYP2C9;CYP2B6;CYP2C8;CYP2D6 common genes common pathways GO:0055114| oxidation-reduction process CYP2D6;CYP2C9;CYP2B6;CYP2C8;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6;CYP2C9 40781:[DB00480 DB01684] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01684|1-Hydroxy-1-Thio-Glycerol PREP common genes common pathways 40782:[DB00480 DB11079] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes PTGS2 common pathways GO:0090050| positive regulation of cell migration involved in sprouting angiogenesis PTGS2 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2 GO:0090271| positive regulation of fibroblast growth factor production PTGS2 GO:0019371| cyclooxygenase pathway PTGS2;PTGS1 GO:0071498| cellular response to fluid shear stress PTGS2 GO:0010942| positive regulation of cell death PTGS2 GO:0006954| inflammatory response PTGS2;PTGS1 GO:0019233| sensory perception of pain PTGS2 GO:0031622| positive regulation of fever generation PTGS2 GO:0050873| brown fat cell differentiation PTGS2 GO:0090362| positive regulation of platelet-derived growth factor production PTGS2 GO:0001525| angiogenesis PTGS2 GO:0010575| positive regulation vascular endothelial growth factor production PTGS2 GO:0071260| cellular response to mechanical stimulus PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2 GO:0006693| prostaglandin metabolic process PTGS2;PTGS1 GO:0030728| ovulation PTGS2 GO:1990776| PTGS2 GO:0042307| positive regulation of protein import into nucleus PTGS2 GO:0009314| response to radiation PTGS2 GO:0050727| regulation of inflammatory response PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2 GO:0042633| hair cycle PTGS2 GO:0031394| positive regulation of prostaglandin biosynthetic process PTGS2 GO:0001516| prostaglandin biosynthetic process PTGS2;PTGS1 GO:0014070| response to organic cyclic compound PTGS2 GO:0033280| response to vitamin D PTGS2 GO:0008217| regulation of blood pressure PTGS2;PTGS1 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2 GO:0045987| positive regulation of smooth muscle contraction PTGS2 GO:0071471| cellular response to non-ionic osmotic stress PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2 GO:0007613| memory PTGS2 GO:0035633| maintenance of blood-brain barrier PTGS2 GO:0007566| embryo implantation PTGS2 GO:0010226| response to lithium ion PTGS2 GO:0051384| response to glucocorticoid stimulus PTGS2 GO:0070542| response to fatty acid PTGS2 GO:0034644| cellular response to UV PTGS2 GO:0090336| positive regulation of brown fat cell differentiation PTGS2 GO:0006633| fatty acid biosynthetic process PTGS2;PTGS1 GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2 GO:0045907| positive regulation of vasoconstriction PTGS2 GO:0055114| oxidation-reduction process PTGS1;PTGS2 GO:0071636| positive regulation of transforming growth factor beta production PTGS2 GO:0006631| fatty acid metabolic process PTGS1;PTGS2 GO:0051926| negative regulation of calcium ion transport PTGS2 GO:0042493| response to drug ABCB1;PTGS2 GO:0009750| response to fructose stimulus PTGS2 GO:0019372| lipoxygenase pathway PTGS2 GO:0010042| response to manganese ion PTGS2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2 GO:0010243| response to organic nitrogen PTGS2 GO:0045986| negative regulation of smooth muscle contraction PTGS2 GO:0071284| cellular response to lead ion PTGS2 GO:0071318| cellular response to ATP PTGS2 GO:0032496| response to lipopolysaccharide PTGS2 GO:0007612| learning PTGS2 GO:0042127| regulation of cell proliferation PTGS2;PTGS1 GO:0034097| response to cytokine stimulus PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2 GO:0045786| negative regulation of cell cycle PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2 GO:0034612| response to tumor necrosis factor PTGS2 GO:0032227| negative regulation of synaptic transmission, dopaminergic PTGS2 GO:0031915| positive regulation of synaptic plasticity PTGS2 GO:0010033| response to organic substance PTGS2 GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2 GO:0030282| bone mineralization PTGS2 GO:0046697| decidualization PTGS2 GO:0007568| aging PTGS2 GO:0071456| cellular response to hypoxia PTGS2 GO:0097756| PTGS2 GO:0034605| cellular response to heat PTGS2 GO:1902219| PTGS2 GO:0032355| response to estradiol stimulus PTGS2 GO:0006979| response to oxidative stress PTGS2;PTGS1 GO:0045429| positive regulation of nitric oxide biosynthetic process PTGS2 GO:0098869| PTGS2;PTGS1 40783:[DB00480 DB02300] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02300|Calcipotriol VDR;MPO;CYP24A1 common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;VDR;PTGS2 GO:0033280| response to vitamin D PTGS2;CYP24A1 GO:0007275| multicellular organismal development TNFSF11;VDR GO:0009887| organ morphogenesis TNFSF11;VDR GO:0006979| response to oxidative stress MPO;PTGS2 GO:0046697| decidualization PTGS2;VDR GO:0007568| aging PTGS2;MPO GO:0055114| oxidation-reduction process CYP24A1;PTGS2;MPO GO:0043066| negative regulation of apoptotic process MPO;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;TNFSF11 GO:0032496| response to lipopolysaccharide PTGS2;MPO 40784:[DB00480 DB08313] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08313|nocodazole HPGDS common genes common pathways GO:0001516| prostaglandin biosynthetic process PTGS2;HPGDS GO:0006633| fatty acid biosynthetic process PTGS2;HPGDS GO:0019371| cyclooxygenase pathway HPGDS;PTGS2 GO:0006629| lipid metabolic process PTGS2;HPGDS GO:0006693| prostaglandin metabolic process HPGDS;PTGS2 GO:0006631| fatty acid metabolic process HPGDS;PTGS2 40785:[DB00480 DB04752] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04752|Phosphatidyl ethanol NR5A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NR5A1 GO:0030154| cell differentiation TNFSF11;NR5A1 40786:[DB00480 DB12747] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB12747|Tertomotide TERT common genes common pathways GO:0043066| negative regulation of apoptotic process TERT;PTGS2 GO:0071456| cellular response to hypoxia TERT;PTGS2 40787:[DB00480 DB13170] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13170|Plecanatide GUCY1A2 common genes common pathways 40788:[DB00480 DB05307] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05307|CHF-1512 DDC common genes common pathways 40789:[DB00480 DB03983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03983|(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V) SUOX common genes common pathways GO:0055114| oxidation-reduction process SUOX;PTGS2 40790:[DB00480 DB00777] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00777|Propiomazine HRH1;HTR2A;HTR2C;DRD2;DRD1;DRD4;ADRA1A;ADRA1B;ADRA1D;CHRM3;CHRM5;CHRM2;CHRM4;CHRM1 common genes common pathways GO:0045987| positive regulation of smooth muscle contraction ADRA1B;PTGS2;ADRA1A;ADRA1D;CHRM3 GO:0008285| negative regulation of cell proliferation PTGS2;ADRA1A;DRD2;CDH5 GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;HTR2A;ADRA1A;ADRA1D;HRH1 GO:0007613| memory DRD1;HTR2A;PTGS2;HRH1 GO:0006954| inflammatory response HRH1;PTGS2 GO:0007275| multicellular organismal development ADRA1B;TNFSF11;ADRA1D GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0043406| positive regulation of MAP kinase activity HTR2A;TNFSF11 GO:0051968| positive regulation of synaptic transmission, glutamatergic DRD1;PTGS2 GO:0007568| aging HTR2A;ADRA1A;PTGS2 GO:0042493| response to drug ABCB1;HTR2C;PTGS2;HTR2A;DRD1;DRD2;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;DRD2 GO:0008284| positive regulation of cell proliferation ADRA1D;CHRM1;HTR2A;PTGS2 GO:0007612| learning DRD1;PTGS2 40791:[DB00480 DB07974] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07974|1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;F10 40792:[DB00480 DB13983] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug ABCB1;GABRG3;PTGS2 GO:0006810| transport GABRA3;GABRA5;GABRA4;GABRA6;GABRA1;GABRG2;ABCB1 40793:[DB00480 DB08383] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08383|4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole PDE10A common genes common pathways 40794:[DB00480 DB00990] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways GO:0055114| oxidation-reduction process CYP19A1;CYP3A4;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40795:[DB00480 DB02895] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02895|3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol GSR common genes common pathways GO:0098869| PTGS2;GSR GO:0055114| oxidation-reduction process PTGS2;GSR 40796:[DB00480 DB06766] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06766|Alcaftadine HRH1 common genes common pathways GO:0006954| inflammatory response PTGS2;HRH1 GO:0045907| positive regulation of vasoconstriction HRH1;PTGS2 GO:0007613| memory HRH1;PTGS2 40797:[DB00480 DB02967] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02967|N-Ethylmaleimide CLC common genes common pathways GO:0007275| multicellular organismal development CLC;TNFSF11 40798:[DB00480 DB07147] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07147|methyl (1R,2S)-2-(hydroxycarbamoyl)-1-{4-[(2-methylquinolin-4-yl)methoxy]benzyl}cyclopropanecarboxylate ADAM17 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;ADAM17 GO:0007155| cell adhesion ADAM17;CDH5 GO:0032496| response to lipopolysaccharide ADAM17;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;ADAM17 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;ADAM17 40799:[DB00480 DB00484] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways GO:0045907| positive regulation of vasoconstriction ADRA2C;PTGS2 GO:0043406| positive regulation of MAP kinase activity ADRA2A;TNFSF11 GO:0008284| positive regulation of cell proliferation ADRA2A;PTGS2 GO:0055114| oxidation-reduction process AOX1;PTGS2 GO:0051926| negative regulation of calcium ion transport ADRA2A;PTGS2 40800:[DB00480 DB01954] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01954|Rolipram PDE4D;PDE4B common genes common pathways GO:0007568| aging PTGS2;PDE4D GO:0010469| regulation of receptor activity PDE4D;TNFSF11 40801:[DB00480 DB08599] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08599|N-[(4-methoxyphenyl)sulfonyl]-D-alanine MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MMP12;TNFSF11 40802:[DB00480 DB05207] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05207|SD118 TNF;IL1R1 common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;TNF GO:0051384| response to glucocorticoid stimulus PTGS2;TNF GO:0043065| positive regulation of apoptotic process PTGS2;TNF GO:0050727| regulation of inflammatory response TNF;PTGS2;IL1R1 GO:0045672| positive regulation of osteoclast differentiation TNF;TNFSF11 GO:0031622| positive regulation of fever generation PTGS2;TNF GO:0043123| positive regulation of I-kappaB kinase/NF-kappaB cascade TNFSF11;TNF GO:0007275| multicellular organismal development TNF;TNFSF11 GO:0006954| inflammatory response TNF;PTGS2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNF;TNFSF11 GO:0006955| immune response TNFSF11;TNF;IL1R1 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;TNF GO:0045429| positive regulation of nitric oxide biosynthetic process TNF;PTGS2 GO:0010469| regulation of receptor activity TNF;TNFSF11 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;TNF GO:0045670| regulation of osteoclast differentiation TNF;TNFSF11 GO:0043406| positive regulation of MAP kinase activity TNFSF11;TNF GO:0010033| response to organic substance PTGS2;TNF GO:0009887| organ morphogenesis TNFSF11;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;TNFSF11 GO:0046330| positive regulation of JNK cascade TNFSF11;TNF GO:0042127| regulation of cell proliferation TNF;PTGS2 GO:0019221| cytokine-mediated signaling pathway TNFSF11;IL1R1 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;TNFSF11 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;TNF GO:0030316| osteoclast differentiation TNF;TNFSF11 40803:[DB00480 DB06677] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06677|Clazosentan EDNRA common genes common pathways GO:0008217| regulation of blood pressure PTGS2;EDNRA 40804:[DB00480 DB07223] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07223|METHYL N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE CTSB common genes common pathways GO:0046697| decidualization CTSB;PTGS2 40805:[DB00480 DB04258] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04258|Seocalcitol VDR common genes common pathways GO:0008285| negative regulation of cell proliferation CDH5;VDR;PTGS2 GO:0007275| multicellular organismal development VDR;TNFSF11 GO:0009887| organ morphogenesis VDR;TNFSF11 GO:0046697| decidualization PTGS2;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;VDR 40806:[DB00480 DB01188] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01188|Ciclopirox ATP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ATP1A1;PTGS2 GO:0071260| cellular response to mechanical stimulus ATP1A1;PTGS2 GO:0008217| regulation of blood pressure PTGS2;ATP1A1 40807:[DB00480 DB08476] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08476|3-AMINO-AZACYCLOTRIDECAN-2-ONE MMP8 common genes common pathways 40808:[DB00480 DB11737] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0051968| positive regulation of synaptic transmission, glutamatergic EGFR;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0043406| positive regulation of MAP kinase activity TNFSF11;EGFR GO:0098609| CDH5;EGFR GO:0045780| positive regulation of bone resorption TNFSF11;EGFR GO:0032355| response to estradiol stimulus CYP1A2;EGFR;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process EGFR;PTGS2 GO:0006979| response to oxidative stress EGFR;PTGS2 GO:0042493| response to drug PTGS2;ABCB1;CYP1A2 GO:0055114| oxidation-reduction process PTGS2;CYP3A5;CYP3A4;CYP1A2 GO:0048661| positive regulation of smooth muscle cell proliferation PTGS2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;TNFSF11 GO:0042127| regulation of cell proliferation EGFR;PTGS2 GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGFR;TNFSF11 GO:0008284| positive regulation of cell proliferation PTGS2;EGFR GO:0014070| response to organic cyclic compound PTGS2;EGFR;CYP1A2 GO:0045907| positive regulation of vasoconstriction PTGS2;EGFR GO:0033138| positive regulation of peptidyl-serine phosphorylation EGFR;PTGS2 GO:0007275| multicellular organismal development EGFR;TNFSF11 GO:0042327| positive regulation of phosphorylation EGFR;TNFSF11 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP3A4 GO:0071260| cellular response to mechanical stimulus PTGS2;EGFR GO:0001503| ossification EGFR;TNFSF11 40809:[DB00480 DB11221] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11221|Dioxybenzone SHBG common genes common pathways 40810:[DB00480 DB06548] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06548|Minodronic acid FDPS;GGPS1 common genes common pathways GO:0006629| lipid metabolic process FDPS;PTGS2 40811:[DB00480 DB00045] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00045|Lyme disease vaccine (recombinant OspA) TLR2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;TLR2 GO:0032496| response to lipopolysaccharide TLR2;PTGS2 GO:0007612| learning PTGS2;TLR2 GO:0070542| response to fatty acid PTGS2;TLR2 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;TLR2 GO:0006955| immune response TLR2;TNFSF11 GO:0006954| inflammatory response PTGS2;TLR2 GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;TLR2 40812:[DB00480 DB02492] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02492|Ghavamiol MAN2A1 common genes common pathways 40813:[DB00480 DB01944] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01944|(S)-blebbistatin MYH14 common genes common pathways 40814:[DB00480 DB04372] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04372|Di-Linoleoyl-3-Sn-Phosphatidylcholine PCTP common genes common pathways 40815:[DB00480 DB00905] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0006693| prostaglandin metabolic process PTGS2;AKR1C3 GO:0031622| positive regulation of fever generation PTGER3;PTGS2 GO:0010942| positive regulation of cell death PTGS2;AKR1C3 GO:0019371| cyclooxygenase pathway PTGS2;AKR1C3 GO:0008284| positive regulation of cell proliferation AKR1C3;PTGFR;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;PTGFR GO:0032496| response to lipopolysaccharide PTGFR;PTGER1;PTGS2 GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;TNFSF11 GO:0055114| oxidation-reduction process AKR1C3;PTGS2 GO:0032355| response to estradiol stimulus PTGS2;PTGFR 40816:[DB00480 DB00466] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00466|Picrotoxin GABRR1;GABRA1;GLRA2;GLRA3;GLRA1;CYP1A1;GLUL common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CYP1A1 GO:0042493| response to drug ABCB1;CYP1A1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A1 GO:0032496| response to lipopolysaccharide PTGS2;CYP1A1 GO:0051968| positive regulation of synaptic transmission, glutamatergic GLUL;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A1 GO:0007568| aging CYP1A1;PTGS2 GO:0006810| transport GABRR1;GABRA1;ABCB1 GO:0051260| protein homooligomerization TNFSF11;GLRA1;GLRA3;GLUL 40817:[DB00480 DB11945] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11945|Avelumab CD274 common genes common pathways GO:0006955| immune response TNFSF11;CD274 GO:0034097| response to cytokine stimulus CD274;PTGS2 40818:[DB00480 DB01786] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01786|D-Alanine SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC16A10 40819:[DB00480 DB04451] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04451|4-Methylpiperazin-1-Yl Carbonyl Group CTSV common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;CTSV GO:0051384| response to glucocorticoid stimulus CTSV;PTGS2 GO:0046697| decidualization CTSV;PTGS2 40820:[DB00480 DB02101] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02101|(S,R)-fidarestat AKR1B1 common genes common pathways GO:0010033| response to organic substance PTGS2;AKR1B1 GO:0043066| negative regulation of apoptotic process PTGS2;AKR1B1 GO:0048661| positive regulation of smooth muscle cell proliferation AKR1B1;PTGS2 GO:0055114| oxidation-reduction process PTGS2;AKR1B1 40821:[DB00480 DB06258] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06258|Bimoclomol HSF1 common genes common pathways GO:0010243| response to organic nitrogen PTGS2;HSF1 GO:0008284| positive regulation of cell proliferation HSF1;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;HSF1 GO:0032496| response to lipopolysaccharide PTGS2;HSF1 GO:0051260| protein homooligomerization TNFSF11;HSF1 GO:0032355| response to estradiol stimulus HSF1;PTGS2 GO:0034605| cellular response to heat PTGS2;HSF1 GO:0008285| negative regulation of cell proliferation CDH5;HSF1;PTGS2 GO:0014070| response to organic cyclic compound HSF1;PTGS2 40822:[DB00480 DB01260] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process CYP3A4;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;TNFSF11 40823:[DB00480 DB05624] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05624|Teverelix GNRHR common genes common pathways GO:0007275| multicellular organismal development GNRHR;TNFSF11 40824:[DB00480 DB02929] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02929|K201 ANXA5 common genes common pathways GO:0010033| response to organic substance ANXA5;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ANXA5 40825:[DB00480 DB04020] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04020|4-(2-{[4-{[3-(4-Chlorophenyl)Propyl]Sulfanyl}-6-(1-Piperazinyl)-1,3,5-Triazin-2-Yl]Amino}Ethyl)Phenol ESR2 common genes common pathways GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity ESR2;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR2 40826:[DB00480 DB07256] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07256|3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE EPHB4 common genes common pathways GO:0007155| cell adhesion EPHB4;CDH5 GO:0001525| angiogenesis PTGS2;EPHB4 GO:0007275| multicellular organismal development TNFSF11;EPHB4 40827:[DB00480 DB05119] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05119|Rilapladib PLA2G7 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G7 40828:[DB00480 DB11770] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11770|Talinolol CYP2D6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0055114| oxidation-reduction process CYP2D6;PTGS2 40829:[DB00480 DB07723] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07723|3-(5-methoxy-1H-indol-3-yl)propanoic acid PPARG common genes common pathways GO:0010033| response to organic substance PPARG;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;TNFSF11 GO:0042493| response to drug PTGS2;PPARG;ABCB1 GO:0014070| response to organic cyclic compound PPARG;PTGS2 GO:0008285| negative regulation of cell proliferation CDH5;PPARG;PTGS2 GO:0008217| regulation of blood pressure PPARG;PTGS2 GO:0043065| positive regulation of apoptotic process PTGS2;PPARG GO:0006629| lipid metabolic process PTGS2;PPARG GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;PPARG 40830:[DB00480 DB08038] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08038|L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide KLK7 common genes common pathways 40831:[DB00480 DB04711] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04711|Iodipamide ALB common genes common pathways GO:0043066| negative regulation of apoptotic process ALB;PTGS2 GO:0098869| ALB;PTGS2 40832:[DB00480 DB03510] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03510|6-O-Phosphoryl Inosine Monophosphate ADSSL1 common genes common pathways 40833:[DB00480 DB01065] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;MPO GO:0008284| positive regulation of cell proliferation PTGS2;CALR GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESR1;RORB GO:0007155| cell adhesion CYP1B1;CDH5 GO:0060749| mammary gland alveolus development ESR1;TNFSF11 GO:0032496| response to lipopolysaccharide CYP1A2;MPO;CYP1A1;PTGS2;IDO1 GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;CALR;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;IDO1;MPO;CYP1A1;CYP1B1;NQO2;CYP1A2;EPX;CYP2C9;CYP19A1 GO:0006979| response to oxidative stress EPX;MPO;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process ESR1;PTGS2 GO:0098869| PTGS2;EPX GO:0032355| response to estradiol stimulus PTGS2;CALR;ESR1;CYP1A2 GO:0007568| aging CYP1A1;MPO;PTGS2 GO:0010033| response to organic substance CYP1A2;CYP1A1;CALR;PTGS2 GO:0055085| transmembrane transport ABCB1;SLC22A8;CALM1 GO:0050727| regulation of inflammatory response ESR1;PTGS2 GO:0043065| positive regulation of apoptotic process IDO1;PTGS2;CYP1B1 GO:0006629| lipid metabolic process PTGS2;CYP1A2;CYP2C9 GO:0010575| positive regulation vascular endothelial growth factor production CYP1B1;PTGS2 GO:0007275| multicellular organismal development RORB;TNFSF11 GO:0001525| angiogenesis CYP1B1;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;ESR1 GO:0006954| inflammatory response PTGS2;IDO1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;CYP1B1 GO:0014070| response to organic cyclic compound CYP1A1;PTGS2;CYP1A2 40834:[DB00480 DB04830] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04830|Buformin SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1 GO:0051260| protein homooligomerization TNFSF11;SLC22A1 GO:0055085| transmembrane transport SLC22A1;ABCB1 40835:[DB00480 DB04664] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04664|Cyclohexyl-pentyl-maltoside CYP2B6 common genes common pathways GO:0055114| oxidation-reduction process CYP2B6;PTGS2 40836:[DB00480 DB01535] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways GO:0033138| positive regulation of peptidyl-serine phosphorylation PTGS2;OPRD1 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;OPRM1 GO:0009314| response to radiation PTGS2;OPRK1;OPRM1 GO:0019233| sensory perception of pain OPRD1;PTGS2;OPRK1;OPRM1 GO:0006955| immune response TNFSF11;OPRK1;OPRD1 GO:0045429| positive regulation of nitric oxide biosynthetic process OPRM1;PTGS2 GO:0071456| cellular response to hypoxia OPRD1;PTGS2 GO:0032496| response to lipopolysaccharide OPRM1;PTGS2 40837:[DB00480 DB04534] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04534|5-Nitroindazole NOS2;NOS3 common genes common pathways GO:0001525| angiogenesis NOS3;PTGS2 GO:0008217| regulation of blood pressure PTGS2;NOS3 GO:0008285| negative regulation of cell proliferation NOS3;CDH5;PTGS2 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process NOS2;PTGS2;NOS3 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 40838:[DB00480 DB00679] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0007275| multicellular organismal development TNFSF11;ADRA1B GO:0019233| sensory perception of pain HTR2A;PTGS2 GO:0006629| lipid metabolic process PTGS2;CYP2D6 GO:0008285| negative regulation of cell proliferation CDH5;PTGS2;DRD2;ADRA1A GO:0045987| positive regulation of smooth muscle contraction ADRA1A;PTGS2;ADRA1B GO:0007613| memory DRD1;HTR2A;PTGS2 GO:0045907| positive regulation of vasoconstriction ADRA1B;PTGS2;HTR2A;ADRA1A GO:0055114| oxidation-reduction process CYP2E1;PTGS2;CYP2C19;CYP2C8;CYP2D6 GO:0042493| response to drug PTGS2;ADRA1A;DRD2;HTR2A;CYP2E1;DRD1;ABCB1 GO:0010243| response to organic nitrogen PTGS2;CYP2E1 GO:0007612| learning PTGS2;DRD1 GO:0008284| positive regulation of cell proliferation PTGS2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;TNFSF11 GO:0055085| transmembrane transport KCNH2;ABCB1 GO:0043406| positive regulation of MAP kinase activity TNFSF11;HTR2A GO:0051968| positive regulation of synaptic transmission, glutamatergic PTGS2;DRD1 GO:0007568| aging ADRA1A;HTR2A;PTGS2 40839:[DB00480 DB08480] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08480|4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN MAOB common genes common pathways GO:0055114| oxidation-reduction process MAOB;PTGS2 GO:0042493| response to drug ABCB1;PTGS2;MAOB GO:0032496| response to lipopolysaccharide PTGS2;MAOB 40840:[DB00480 DB06897] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways GO:0043066| negative regulation of apoptotic process PTGS2;PLK1 GO:0016567| protein ubiquitination PLK1;CRBN GO:0000086| G2/M transition of mitotic cell cycle ABCB1;PLK1 40841:[DB00480 DB05150] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05150|CAD106 APP common genes common pathways GO:0006979| response to oxidative stress APP;PTGS2 GO:0045429| positive regulation of nitric oxide biosynthetic process APP;PTGS2 GO:0051260| protein homooligomerization APP;TNFSF11 GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;APP GO:0007612| learning APP;PTGS2 GO:0046330| positive regulation of JNK cascade APP;TNFSF11 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;APP GO:0007155| cell adhesion CDH5;APP GO:0008285| negative regulation of cell proliferation PTGS2;APP;CDH5 GO:0019722| calcium-mediated signaling TNFSF11;APP GO:0007613| memory PTGS2;APP GO:0033138| positive regulation of peptidyl-serine phosphorylation APP;PTGS2 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity TNFSF11;APP GO:0051092| positive regulation of NF-kappaB transcription factor activity APP;TNFSF11 GO:0042327| positive regulation of phosphorylation APP;TNFSF11 GO:0043065| positive regulation of apoptotic process APP;PTGS2 40842:[DB00480 DB01381] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0042493| response to drug SLC6A2;PTGS2;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C9 GO:0055085| transmembrane transport ABCB1;SLC6A2 GO:0006810| transport GABRB2;SLC6A2;GABRA1;ABCB1;GABRG2 GO:0051260| protein homooligomerization GLRA1;TNFSF11 GO:0006629| lipid metabolic process CYP2C9;PLA2G2A;PTGS2 40843:[DB00480 DB01208] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes ABCB1 common pathways GO:0043065| positive regulation of apoptotic process PTGS2;TOP2A GO:0006629| lipid metabolic process PTGS2;CYP1A2 GO:0072089| stem cell proliferation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 GO:0006855| drug transmembrane transport SLC22A5;ABCC2;ABCB1 GO:1901529| ABCB1 GO:0032496| response to lipopolysaccharide ABCC2;CYP1A2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;TNFSF11 GO:0042493| response to drug ABCB1;ABCC2;CYP1A2;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0032355| response to estradiol stimulus PTGS2;CYP1A2 GO:0006810| transport ABCC2;ABCB1 GO:0006979| response to oxidative stress PTGS2;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLC22A5 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0010033| response to organic substance PTGS2;CYP1A2 40844:[DB00480 DB01686] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01686|N,N-dimethylarginine NOS2;NOS3 common genes common pathways GO:0001525| angiogenesis PTGS2;NOS3 GO:0008217| regulation of blood pressure NOS3;PTGS2 GO:0008285| negative regulation of cell proliferation PTGS2;CDH5;NOS3 GO:0051926| negative regulation of calcium ion transport NOS3;PTGS2 GO:0055114| oxidation-reduction process NOS3;PTGS2;NOS2 GO:0032496| response to lipopolysaccharide NOS2;PTGS2 GO:0042127| regulation of cell proliferation PTGS2;NOS2 40845:[DB00480 DB08620] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08620|{(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide CHRFAM7A common genes common pathways 40846:[DB00480 DB13083] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB13083|Talarozole CYP26A1 common genes common pathways GO:0055114| oxidation-reduction process CYP26A1;PTGS2 40847:[DB00480 DB04287] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04287|(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid PLA2G2A common genes common pathways GO:0006629| lipid metabolic process PTGS2;PLA2G2A 40848:[DB00480 DB08354] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08354|2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE CSNK2A1 common genes common pathways GO:0008284| positive regulation of cell proliferation PTGS2;CSNK2A1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;CSNK2A1 40849:[DB00480 DB00403] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00403|Ceruletide CCKAR common genes common pathways 40850:[DB00480 DB04150] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04150|Threonine Derivative PAM common genes common pathways GO:0042493| response to drug ABCB1;PAM;PTGS2 GO:0055114| oxidation-reduction process PTGS2;PAM GO:0051260| protein homooligomerization PAM;TNFSF11 GO:0032355| response to estradiol stimulus PTGS2;PAM GO:0051384| response to glucocorticoid stimulus PAM;PTGS2 40851:[DB00480 DB04716] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04716|2-(1,1-DIMETHYLETHYL)9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLIN-7-ONE JAK2;DAPK3;JAK1;JAK3;TYK2 common genes common pathways GO:0043065| positive regulation of apoptotic process JAK2;PTGS2;DAPK3 GO:0050727| regulation of inflammatory response PTGS2;JAK2 GO:0006954| inflammatory response PTGS2;JAK3 GO:0051091| positive regulation of sequence-specific DNA binding transcription factor activity JAK2;TNFSF11 GO:0030154| cell differentiation JAK2;TYK2;JAK1;TNFSF11 GO:0008285| negative regulation of cell proliferation CDH5;JAK2;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;JAK2 GO:0042127| regulation of cell proliferation TYK2;JAK2;PTGS2;JAK1 GO:0032496| response to lipopolysaccharide PTGS2;JAK2 GO:0019221| cytokine-mediated signaling pathway JAK2;TNFSF11 GO:0045429| positive regulation of nitric oxide biosynthetic process JAK2;PTGS2 GO:0006979| response to oxidative stress JAK2;PTGS2 GO:0033209| tumor necrosis factor-mediated signaling pathway TNFSF11;JAK2 GO:0034612| response to tumor necrosis factor JAK2;PTGS2 40852:[DB00480 DB06835] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06835|(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID CPB1 common genes common pathways 40853:[DB00480 DB01003] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01003|Cromoglicic acid KCNMA1;S100P common genes common pathways GO:0010033| response to organic substance S100P;PTGS2 GO:0055085| transmembrane transport ABCB1;KCNMA1 GO:0043065| positive regulation of apoptotic process KCNMA1;PTGS2 40854:[DB00480 DB05311] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05311|Ecallantide KLKB1 common genes common pathways GO:0006954| inflammatory response PTGS2;KLKB1 40855:[DB00480 DB11597] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11597|Human Rho(D) immune globulin RHD common genes common pathways 40856:[DB00480 DB07033] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07033|5-HYDROXY-3-[(1R)-1-(1H-PYRROL-2-YL)ETHYL]-2H-INDOL-2-ONE PDPK1 common genes common pathways GO:0019722| calcium-mediated signaling PDPK1;TNFSF11 40857:[DB00480 DB06902] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06902|4-(1-methyl-1-phenylethyl)phenol ESRRG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;ESRRG 40858:[DB00480 DB00551] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00551|Acetohydroxamic acid ureC;MMP12 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MMP12 40859:[DB00480 DB11740] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11740|MK-1775 WEE1 common genes common pathways GO:0000086| G2/M transition of mitotic cell cycle ABCB1;WEE1 40860:[DB00480 DB00778] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes ABCB1 common pathways GO:0006855| drug transmembrane transport ABCB1 GO:0042908| xenobiotic transport ABCB1 GO:0072089| stem cell proliferation ABCB1 GO:0045332| phospholipid translocation ABCB1 GO:0047484| regulation of response to osmotic stress ABCB1 GO:0006629| lipid metabolic process CYP3A4;PTGS2 GO:0000086| G2/M transition of mitotic cell cycle ABCB1 GO:0055085| transmembrane transport ABCB1 GO:0006810| transport ABCB1 GO:0099040| ABCB1 GO:0055114| oxidation-reduction process CYP3A4;CYP2B6;PTGS2 GO:2001225| regulation of chloride transport ABCB1 GO:0042493| response to drug ABCB1;PTGS2 GO:1901529| ABCB1 40861:[DB00480 DB03408] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03408|gamma-Glutamylcysteine GSS common genes common pathways GO:0034612| response to tumor necrosis factor GSS;PTGS2 GO:0006979| response to oxidative stress PTGS2;GSS GO:0007568| aging GSS;PTGS2 40862:[DB00480 DB04209] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04209|Dequalinium XIAP;CNGA1;KCNMA1 common genes common pathways GO:0016567| protein ubiquitination XIAP;CRBN GO:0043066| negative regulation of apoptotic process PTGS2;XIAP GO:0042127| regulation of cell proliferation PTGS2;XIAP GO:0055085| transmembrane transport CNGA1;ABCB1;KCNMA1 GO:0006810| transport CNGA1;ABCB1 GO:0043154| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process PTGS2;XIAP GO:0043065| positive regulation of apoptotic process KCNMA1;PTGS2 GO:0050727| regulation of inflammatory response PTGS2;XIAP 40863:[DB00480 DB01830] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01830|{4-[2-Acetylamino-2-(3-Carbamoyl-2-Cyclohexylmethoxy-6,7,8,9-Tetrahydro-5h-Benzocyclohepten-5ylcarbamoyl)-Ethyl]-2-Phosphono-Phenyl}-Phosphonic Acid LCK common genes common pathways GO:0050870| positive regulation of T cell activation LCK;TNFSF11 GO:0042127| regulation of cell proliferation PTGS2;LCK GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;LCK GO:0042493| response to drug ABCB1;PTGS2;LCK 40864:[DB00480 DB11475] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11475|Tylosin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0055114| oxidation-reduction process PTGS2;CYP3A4 40865:[DB00480 DB08933] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08933|Luliconazole CYP3A4;CYP2C19 common genes common pathways GO:0055114| oxidation-reduction process CYP2C19;PTGS2;CYP3A4 GO:0006629| lipid metabolic process PTGS2;CYP3A4 40866:[DB00480 DB05465] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways GO:0007275| multicellular organismal development PDGFD;TNFSF11 GO:0030154| cell differentiation TNFSF11;FLT3 GO:0019221| cytokine-mediated signaling pathway FLT3;TNFSF11 GO:0010243| response to organic nitrogen PTGS2;FLT3 GO:0048661| positive regulation of smooth muscle cell proliferation PDGFD;PTGS2 GO:0008284| positive regulation of cell proliferation PTGS2;PDGFD;FLT3 GO:0043406| positive regulation of MAP kinase activity PDGFD;TNFSF11;FLT3 GO:0010469| regulation of receptor activity TNFSF11;PDGFD 40867:[DB00480 DB11632] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB11632|Opicapone COMT;CYP2C19;CYP2C8 common genes common pathways GO:0014070| response to organic cyclic compound PTGS2;COMT GO:0042493| response to drug PTGS2;COMT;ABCB1 GO:0055114| oxidation-reduction process PTGS2;CYP2C19;CYP2C8 GO:0032496| response to lipopolysaccharide COMT;PTGS2 GO:0007612| learning PTGS2;COMT 40868:[DB00480 DB02398] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02398|6-[N-(4-(Aminomethyl)Phenyl)Carbamyl]-2-Naphthalenecarboxamidine PLAU common genes common pathways GO:0010469| regulation of receptor activity PLAU;TNFSF11 GO:0042127| regulation of cell proliferation PLAU;PTGS2 40869:[DB00480 DB02676] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02676|2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol PDE4D common genes common pathways GO:0010469| regulation of receptor activity PDE4D;TNFSF11 GO:0007568| aging PTGS2;PDE4D 40870:[DB00480 DB02555] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB02555|SP4160 IL2 common genes common pathways GO:0006955| immune response IL2;TNFSF11 GO:0010469| regulation of receptor activity IL2;TNFSF11 GO:0050728| negative regulation of inflammatory response CDH5;IL2 GO:0007155| cell adhesion IL2;CDH5 GO:0043066| negative regulation of apoptotic process IL2;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;IL2 GO:0008284| positive regulation of cell proliferation PTGS2;IL2 40871:[DB00480 DB08891] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08891|Arbaclofen GABBR1;GABBR2 common genes common pathways 40872:[DB00480 DB08618] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08618|3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER IGHG2 common genes common pathways 40873:[DB00480 DB01884] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01884|2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One DPP4 common genes common pathways GO:0007155| cell adhesion CDH5;DPP4 GO:0008284| positive regulation of cell proliferation DPP4;PTGS2 40874:[DB00480 DB07913] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB07913|HOMOPHENYLALANINYLMETHANE CTSF common genes common pathways 40875:[DB00480 DB04677] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04677|N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE MAOB common genes common pathways GO:0032496| response to lipopolysaccharide PTGS2;MAOB GO:0055114| oxidation-reduction process PTGS2;MAOB GO:0042493| response to drug ABCB1;PTGS2;MAOB 40876:[DB00480 DB06160] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB06160|Garenoxacin CYP1A2 common genes common pathways GO:0032496| response to lipopolysaccharide CYP1A2;PTGS2 GO:0055114| oxidation-reduction process PTGS2;CYP1A2 GO:0042493| response to drug PTGS2;CYP1A2;ABCB1 GO:0032355| response to estradiol stimulus CYP1A2;PTGS2 GO:0010033| response to organic substance PTGS2;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;PTGS2 GO:0014070| response to organic cyclic compound PTGS2;CYP1A2 40877:[DB00480 DB04079] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04079|Heptane-1,2,3-Triol RHO common genes common pathways 40878:[DB00480 DB03087] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03087|2-(Sec-Butyl)Thiazole LCN9 common genes common pathways 40879:[DB00480 DB04839] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0051092| positive regulation of NF-kappaB transcription factor activity TNFSF11;AR GO:0042327| positive regulation of phosphorylation TNFSF11;AR GO:0006629| lipid metabolic process PTGS2;CYP3A4 GO:0008285| negative regulation of cell proliferation AR;PTGS2;CDH5 GO:0055114| oxidation-reduction process PTGS2;CYP19A1;CYP3A4 GO:0008284| positive regulation of cell proliferation AR;PTGS2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;TNFSF11 GO:0060749| mammary gland alveolus development AR;TNFSF11 GO:0006810| transport ABCB1;AR 40880:[DB00480 DB08855] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB08855|Leukotriene C4 CYSLTR1;CYSLTR2;ABCC1;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLCO1B1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;PTGS2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0010942| positive regulation of cell death CYSLTR2;PTGS2 GO:0006955| immune response TNFSF11;CYSLTR2 40881:[DB00480 DB03881] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03881|MT-Immucillin-H PNP common genes common pathways GO:0042493| response to drug PTGS2;ABCB1;PNP GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;PNP GO:0006955| immune response PNP;TNFSF11 40882:[DB00480 DB01276] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01276|Exenatide GLP1R;ALB common genes common pathways GO:0098869| ALB;PTGS2 GO:0043066| negative regulation of apoptotic process PTGS2;ALB 40883:[DB00480 DB14040] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB14040|Eptinezumab CALCA;CALCB common genes common pathways GO:0008217| regulation of blood pressure CALCA;PTGS2 GO:0010469| regulation of receptor activity CALCB;TNFSF11;CALCA 40884:[DB00480 DB01949] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways GO:0007566| embryo implantation PTGS2;MMP9 GO:0043065| positive regulation of apoptotic process PTGS2;MMP9 GO:0001503| ossification MMP9;TNFSF11 GO:0043066| negative regulation of apoptotic process MMP9;PTGS2 40885:[DB00480 DB05217] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB05217|GMX1777 NAMPT common genes common pathways GO:0010469| regulation of receptor activity TNFSF11;NAMPT GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;NAMPT GO:0008284| positive regulation of cell proliferation PTGS2;NAMPT GO:0048661| positive regulation of smooth muscle cell proliferation NAMPT;PTGS2 GO:0034356| NAD biosynthesis via nicotinamide riboside salvage pathway PTGS2;NAMPT GO:0014070| response to organic cyclic compound PTGS2;NAMPT 40886:[DB00480 DB03632] DB00480|Lenalidomide CRBN;TNFSF11;CDH5;PTGS2;ABCB1 DB03632|Argifin CHIT1 common genes common pathways GO:0006955| immune response CHIT1;TNFSF11 40887:[DB00399 DB07543] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways 40888:[DB00399 DB11730] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0042493| response to drug CDK4;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 40889:[DB00399 DB00413] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;SLC22A2;ABCC1 GO:0042493| response to drug DRD1;HTR2A;DRD2;HTR2B;ABCC1;HTR2C;HTR1B;DRD3 GO:0006855| drug transmembrane transport SLC22A2;ABCC1;SLC22A1 GO:0016032| viral reproduction FDPS;HTR2A 40890:[DB00399 DB01224] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01224|Quetiapine HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP3A4;CYP2C19;CYP2D6;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0016032| viral reproduction FDPS;HTR2A GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP2C19;FDPS;CYP2D6;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug HTR2C;DRD3;ABCB1;HTR1B;HTR2A;DRD1;ADRA1A;DRD2;ABCC1 40891:[DB00399 DB06605] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2C9;CYP3A4;CYP3A5;CYP2C8;CYP2C19 GO:0042493| response to drug ABCG2;ABCC1;ABCB1;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2C9 40892:[DB00399 DB01179] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways 40893:[DB00399 DB05127] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05127|ANA971 TLR7 common genes common pathways 40894:[DB00399 DB01148] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways 40895:[DB00399 DB01594] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;ABCC1 GO:0006810| transport GABRG2;GABRB3;GABRA1;GABRB1;GABRR1;ABCC1;GABRR2;GABRD;GABRA5;GABRA3;GABRB2 40896:[DB00399 DB00645] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00645|Dyclonine SCN10A common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCC1 40897:[DB00399 DB04863] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction FDPS;ITGB3 40898:[DB00399 DB01580] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2 GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0055085| transmembrane transport ABCC1;SLC22A2 GO:0008202| steroid metabolic process FDPS;CYP2D6 40899:[DB00399 DB00196] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS;CYP11B1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP11B1 GO:0042493| response to drug ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;FDPS;CYP2C19;CYP3A5;CYP11B1;CYP3A7 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 40900:[DB00399 DB02789] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCC1 GO:0006629| lipid metabolic process SULT2B1;FDPS;CYP3A4 GO:0008202| steroid metabolic process NR1I2;FDPS;SULT2B1;CYP3A4 GO:0055085| transmembrane transport SLC10A6;ABCC1 GO:0008203| cholesterol metabolic process SULT2B1;FDPS 40901:[DB00399 DB08911] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process FDPS;CYP3A4 40902:[DB00399 DB00087] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FCGR2B;FDPS 40903:[DB00399 DB06803] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;CYP1A2;FDPS GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2C9 40904:[DB00399 DB00175] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes common pathways GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0006629| lipid metabolic process HMGCR;SLC16A1;FDPS GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006694| steroid biosynthetic process FDPS;HMGCR GO:0042493| response to drug ABCG2;ABCC1;ABCB1;ABCC2 GO:0099133| ABCC1;ABCC2 GO:0008203| cholesterol metabolic process HMGCR;FDPS GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1;FDPS GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0055085| transmembrane transport ABCB11;SLC22A8;SLCO1B1;SLC22A7;SLC22A6;SLCO2B1;SLCO1A2;SLC22A11;ABCC1;ABCG2;SLCO1B3;SLC16A1;ABCB1;ABCC2 GO:0008299| isoprenoid biosynthetic process GGPS1;FDPS;HMGCR GO:0008202| steroid metabolic process FDPS;CYP2C8;HMGCR GO:0006810| transport ABCB11;ABCG2;ABCC1;ABCC2;ABCB1 40905:[DB00399 DB00940] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00940|Methantheline CHRM1;HRH2 common genes common pathways 40906:[DB00399 DB00098] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways GO:0016032| viral reproduction CD86;ITGB1;ITGAV;FDPS;ITGB3;CD4;FCGR2B 40907:[DB00399 DB00816] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00816|Orciprenaline ADRB2 common genes common pathways 40908:[DB00399 DB00543] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0016032| viral reproduction HTR2A;FDPS GO:0042493| response to drug HTR2C;GABRG3;SLC6A4;DRD3;HTR1B;HTR2A;DRD1;DRD2;ADRA1A;SLC6A3;SLC6A2;ABCC1;HTR2B GO:0006810| transport GABRG2;GABRA1;GABRB3;SLC6A2;ABCC1;GABRD;GABRB1;GABRA4;GABRA6;GABRA5;GABRA3;GABRB2 GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCC1;SLC6A3 40909:[DB00399 DB01165] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes ABCC1 common pathways GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC1;ABCC2;CYP1A2 GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC1;ABCB11;ABCC2 GO:0055085| transmembrane transport SLC22A5;ABCB11;SLC22A6;ABCC1;SLC22A4;ABCC2 GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0034775| glutathione transmembrane transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1 GO:0006855| drug transmembrane transport ABCC1;SLC22A5;ABCC2 40910:[DB00399 DB00671] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCC1 GO:0055085| transmembrane transport SLC15A1;ABCC1;SLC15A2;SLC22A5 GO:0006810| transport SLC15A1;ABCC1;SLC15A2 40911:[DB00399 DB03410] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03410|4-hydroxycoumarin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 40912:[DB00399 DB06685] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06685|Laquinimod CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 40913:[DB00399 DB01618] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0042493| response to drug ABCC1;HTR2A;DRD2 GO:0016032| viral reproduction FDPS;HTR2A 40914:[DB00399 DB05111] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05111|Fontolizumab IFNG common genes common pathways 40915:[DB00399 DB01023] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB1;CACNA1C;CACNA1D;ABCB11;CALM1;CACNA1H;ABCC1;CACNA1S 40916:[DB00399 DB01029] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C9;CYP2C8 GO:0060326| cell chemotaxis AGTR1;ABCC1 GO:0042493| response to drug JUN;ABCC1 GO:0006629| lipid metabolic process PTGS1;FDPS;CYP2C9;CYP3A4 40917:[DB00399 DB00866] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;FDPS 40918:[DB00399 DB06233] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 40919:[DB00399 DB00843] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0042493| response to drug ABCC1;HTR2A GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS GO:0016032| viral reproduction HTR2A;FDPS 40920:[DB00399 DB00987] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport SLC22A1;ABCC10;ABCC1 GO:0099133| ABCC10;ABCC1 40921:[DB00399 DB05258] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05258|Natural alpha interferon IFNAR1 common genes common pathways 40922:[DB00399 DB09160] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 40923:[DB00399 DB08877] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 40924:[DB00399 DB11641] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB5;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB5;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB5;ABCB1 40925:[DB00399 DB01211] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01211|Clarithromycin rplJ;KCNH2;SLCO1B1;SLCO1B3;CYP3A4;CYP3A5;CYP2C19;CYP3A7;SLC22A7;ABCB1;ABCB11 common genes common pathways GO:0055085| transmembrane transport SLC22A7;ABCB11;SLCO1B1;ABCC1;SLCO1B3;KCNH2;ABCB1 GO:0006810| transport ABCB1;ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP2C19;CYP3A5;CYP3A7;CYP3A4;FDPS GO:0042493| response to drug ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS 40926:[DB00399 DB00292] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0042908| xenobiotic transport SLC2A1;ABCC1 GO:0006629| lipid metabolic process CYP11B1;CYP11B2;FDPS GO:0055085| transmembrane transport ABCC1;SLC2A1 GO:0006810| transport GABRG2;GABRB3;GABRA1;GABRD;ABCC1;GABRA4;GABRA6;GABRB1;GABRB2;GABRA3;GABRA5 GO:0008202| steroid metabolic process FDPS;CYP11B2;CYP11B1 GO:0042493| response to drug ABCC1;GABRG3 GO:0006694| steroid biosynthetic process FDPS;CYP19A1;CYP11B1;CYP11B2 40927:[DB00399 DB01218] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4;CYP3A5;CYP2C8 GO:0055085| transmembrane transport KCNH2;ABCC1 40928:[DB00399 DB01099] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01099|Flucytosine DNMT1 common genes common pathways 40929:[DB00399 DB01204] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes ABCC1 common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0034775| glutathione transmembrane transport ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0060326| cell chemotaxis ABCC1 GO:0099133| ABCC1 GO:0042493| response to drug ABCB1;CYP2E1;ABCG2;ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP2E1;FDPS;CYP1B1;CYP3A4 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport ABCG2;ABCC1;ABCB1 40930:[DB00399 DB06267] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5 40931:[DB00399 DB06660] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06660|Saredutant TACR2 common genes common pathways 40932:[DB00399 DB09090] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CACNA1S;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 40933:[DB00399 DB12836] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 40934:[DB00399 DB00139] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process HSD17B6;FDPS GO:0042493| response to drug ABCC1;OXCT1 GO:0055085| transmembrane transport SLC13A2;ABCC1;SLC13A1;SLC22A8;SLC13A3 GO:0008202| steroid metabolic process HSD17B6;FDPS GO:0006810| transport SLC13A2;ABCC1 40935:[DB00399 DB00736] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00736|Esomeprazole ATP4A;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP2C19;CYP3A4;FDPS GO:0006810| transport ATP4A;ABCC1 40936:[DB00399 DB01198] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;FDPS;CYP2C9;CYP3A4 GO:0006810| transport GABRA1;ABCC1;GABRA5;GABRA3 GO:0008202| steroid metabolic process CYP2E1;CYP2C8;CYP2C9;FDPS;TSPO;CYP3A4 GO:0042493| response to drug CYP2E1;ABCC1;TSPO GO:0006694| steroid biosynthetic process TSPO;FDPS 40937:[DB00399 DB00854] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways 40938:[DB00399 DB00623] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00623|Fluphenazine DRD2;DRD1;CALM1;AR;HTR2A;HTR2C;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042493| response to drug ABCC1;DRD2;DRD1;CYP2E1;HTR2A;ABCB1;HTR2C GO:0055085| transmembrane transport ABCC1;CALM1;ABCB1 GO:0006810| transport ABCC1;AR;ABCB1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP2E1 40939:[DB00399 DB14050] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0006629| lipid metabolic process DAGLA;TRPV1;FDPS GO:0006810| transport ABCC1;TRPV2;TRPV1 GO:0055085| transmembrane transport TRPA1;TRPV2;ABCC1;TRPV1 GO:0042493| response to drug ABCC1;TRPA1 40940:[DB00399 DB00622] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;CYP2E1;ADRA1A;ABCC1 GO:0008202| steroid metabolic process CYP2D6;CYP2B6;FDPS;CYP3A4;CYP3A5;CYP2E1;CYP2C19;CYP2C8 GO:0006810| transport ABCB1;ABCC1;ABCB11 GO:0055085| transmembrane transport ABCB1;ABCB11;SLCO1B1;CACNA1D;CACNA1C;CALM1;ABCC1 40941:[DB00399 DB00119] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process FDPS;SLC16A1;PC GO:0042493| response to drug ABAT;ABCC1 GO:0055085| transmembrane transport SLC16A10;SLC16A4;SLC16A7;SLC16A2;SLC16A1;ABCC1;SLCO2A1;SLC16A8;SLC16A6;SLC16A5;SLC16A3 GO:0006810| transport SLC16A2;ABCC1 40942:[DB00399 DB11201] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCC1 GO:0006629| lipid metabolic process FDPS;PTGS1;PTGS2 40943:[DB00399 DB00370] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0006810| transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP2C8;CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 GO:0055085| transmembrane transport ABCC1;SLC6A2;SLC6A3;SLC6A4 GO:0042493| response to drug CYP1A2;HTR2C;SLC6A4;DRD3;DRD1;HTR2A;ADRA1A;DRD2;SLC6A3;HTR2B;SLC6A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2 GO:0016032| viral reproduction HTR2A;FDPS 40944:[DB00399 DB01118] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4;PPARG GO:0006855| drug transmembrane transport SLC22A2;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug CYP1A1;ABCC1;CYP1A2;PPARG;ABCB1 GO:0055085| transmembrane transport KCNH2;ABCB1;ABCB11;SLC22A2;CACNA1H;ABCC1 GO:0006810| transport ABCB1;ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A7;CYP1A1;CYP3A5;CYP2A6;CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6 40945:[DB00399 DB00392] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCC1 40946:[DB00399 DB00775] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction ITGB3;FDPS 40947:[DB00399 DB00768] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 40948:[DB00399 DB00483] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways 40949:[DB00399 DB00416] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00416|Metocurine Iodide CHRNA2 common genes common pathways 40950:[DB00399 DB01036] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01036|Tolterodine CHRM3;CHRM2;CHRM5;CHRM1;CHRM4;CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2C9;CYP2D6;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS 40951:[DB00399 DB06506] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process FDPS;CYP2D6 40952:[DB00399 DB00960] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0042493| response to drug HTR1B;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2D6 40953:[DB00399 DB14568] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;FDPS;CYP2B6;CYP2C9 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport SLC22A8;ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 40954:[DB00399 DB09273] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0042493| response to drug ADORA2A;ABCC1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS 40955:[DB00399 DB00290] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways GO:0042493| response to drug ABCC1;BLMH 40956:[DB00399 DB00732] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00732|Atracurium besylate CHRNA2 common genes common pathways 40957:[DB00399 DB14597] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14597|Lanadelumab KLKB1 common genes common pathways 40958:[DB00399 DB06739] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0042493| response to drug ABCC1;TBXA2R GO:0008202| steroid metabolic process CYP3A4;CYP2A6;FDPS;CYP2C9;CYP2B6;CYP2C8;CYP2C19 GO:0006629| lipid metabolic process PTGS1;CYP3A4;FDPS;CYP2C9 40959:[DB00399 DB00296] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCC1;SCN10A GO:0008202| steroid metabolic process CYP3A4;CYP2B6;CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS 40960:[DB00399 DB07670] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways 40961:[DB00399 DB01087] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS;CYP1A2 GO:0016032| viral reproduction FDPS;KRT7 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;ABCC1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP1A2;CYP1B1;CYP3A4;CYP1A1 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 40962:[DB00399 DB11753] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;SLCO2A1;ABCC1;SLCO1B1;SLCO2B1;ABCB1;SLC47A1;SLCO1B3 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2B6;CYP2C9;CYP2C8;CYP2C19 GO:0042493| response to drug ABCC1;CYP1A2;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;SLC47A1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6 40963:[DB00399 DB01124] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0099133| ABCC1;ABCC8 GO:0042493| response to drug ABCC1;ABCC8 GO:0055085| transmembrane transport SLC15A1;ABCC8;SLCO1A2;ABCC1;SLC15A2;SLCO2B1;SLC22A6 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;FDPS;CYP2C9 GO:0006810| transport SLC15A1;ABCC1;SLC15A2 GO:0006629| lipid metabolic process CYP2C9;FDPS 40964:[DB00399 DB00997] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes ABCC1 common pathways GO:0099133| ABCC10;ABCC6;ABCC1;ABCC3;ABCC2 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug POR;ABCB1;ABCC2;ABCC6;ABCG2;ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0055085| transmembrane transport SLC22A16;ABCC3;ABCB1;ABCC2;ABCC10;ABCB11;RALBP1;ABCC6;ABCB8;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP2B6;CYP2D6;AKR1C3;FDPS;CYP1B1;CYP3A4 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC6;ABCB11;ABCC1;ABCG2;ABCB8;ABCC3;ABCB1;ABCC2 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006855| drug transmembrane transport ABCC3;ABCC2;ABCB1;RALBP1;ABCG2;ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1;ABCC3 40965:[DB00399 DB00266] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;FDPS 40966:[DB00399 DB00800] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A;DRD1 40967:[DB00399 DB05676] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 40968:[DB00399 DB06694] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A 40969:[DB00399 DB11587] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11587|Etafedrine ADRB2 common genes common pathways 40970:[DB00399 DB06469] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 40971:[DB00399 DB14583] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0006810| transport ABCC1;AR GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 40972:[DB00399 DB08867] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0042493| response to drug ABCC1;CYP1A2 GO:0006810| transport AR;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2 40973:[DB00399 DB01251] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0099133| ABCC8;ABCC1 GO:0042493| response to drug ABCC8;ABCC1 GO:0055085| transmembrane transport ABCC8;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;FDPS 40974:[DB00399 DB09235] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport CACNA1I;ABCC1 GO:0055085| transmembrane transport CACNA1C;ABCC1;CACNA1I GO:0006629| lipid metabolic process FDPS;CYP3A4 40975:[DB00399 DB04725] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways GO:0006691| leukotriene metabolic process ABCC1;ALOX5 GO:0042493| response to drug ABCC1;PTGS2 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;FDPS GO:0006629| lipid metabolic process PTGS2;PLA2G2E;FDPS;CYP2C9 40976:[DB00399 DB00153] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 40977:[DB00399 DB00358] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ADORA2A;ABCC1;BCHE;ABCB1 GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 40978:[DB00399 DB00770] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0042493| response to drug ABCC1;ABCC4 GO:0099133| ABCC5;ABCC4;ABCC1 GO:0055085| transmembrane transport ABCC4;ABCC5;SLC22A6;SLCO2B1;ABCC1;SLCO2A1;SLCO3A1 GO:0006810| transport ABCC5;ABCC1 40979:[DB00399 DB09256] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;TYMS;CYP2E1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2A6;CYP3A5;CYP2E1;CYP2C8 40980:[DB00399 DB09229] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0055085| transmembrane transport CACNA1S;ABCC1;CACNA1D;CACNA1C;CACNA1F GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0042493| response to drug ABCC1;ADRA1A GO:0006629| lipid metabolic process CYP3A4;FDPS 40981:[DB00399 DB09078] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0006810| transport ABCG2;ABCC1;ABCB11;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2D6;CYP2B6;CYP2C9;FDPS;CYP1A2 GO:0055085| transmembrane transport SLC22A2;SLC22A6;ABCB11;SLC22A8;SLCO1B1;ABCG2;ABCC1;ABCB1 GO:0060326| cell chemotaxis KIT;ABCC1 GO:0042493| response to drug ABCC1;ABCG2;CYP1A2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;ABCG2;ABCC1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 GO:0016032| viral reproduction FDPS;KDR 40982:[DB00399 DB00417] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways GO:0006810| transport ABCC1;SLC15A1 GO:0055085| transmembrane transport ABCC1;SLC15A1 40983:[DB00399 DB11691] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP3A4;FDPS GO:0055085| transmembrane transport ABCB5;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCC1;ABCB5 GO:0006855| drug transmembrane transport ABCC1;ABCB5 40984:[DB00399 DB06311] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06311|Darapladib PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;FDPS 40985:[DB00399 DB00701] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00701|Amprenavir pol;CYP3A4;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A5;ABCB1;ABCC1;SLCO1B1 common genes ABCC1 common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP2C9;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1;SLCO1B1 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C8 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0099133| ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC1;ABCB1 GO:0060326| cell chemotaxis ABCC1 40986:[DB00399 DB00882] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP11A1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1;CYP1A2;CYP11A1;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1;CYP1A1;CYP2E1 GO:0006694| steroid biosynthetic process CYP19A1;CYP11A1;FDPS GO:0008203| cholesterol metabolic process FDPS;CYP11A1 40987:[DB00399 DB01248] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes ABCC1 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1;ABCC2 GO:0042908| xenobiotic transport ABCB1;NR1I2;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0099133| ABCC2;ABCC1;ABCC10 GO:0042493| response to drug BCL2;ABCB1;ABCC2;ABCC1;ABCG2 GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0055085| transmembrane transport BCL2;SLCO1B3;ABCB1;ABCC2;ABCC10;SLC22A7;ABCC1;ABCG2 GO:0006810| transport ABCC2;ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process FDPS;NR1I2;CYP3A4;CYP1B1;CYP3A7;CYP3A5 GO:0009235| cobalamin metabolic process ABCC1 40988:[DB00399 DB00269] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0006694| steroid biosynthetic process CYP19A1;FDPS 40989:[DB00399 DB00497] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4;CYP3A5 40990:[DB00399 DB05420] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05420|Gallium maltolate RRM1 common genes common pathways 40991:[DB00399 DB08903] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 40992:[DB00399 DB08931] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0042493| response to drug ABCC1;ABCG2;CYP1A1 GO:0055085| transmembrane transport ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP1A1;CYP3A4;FDPS GO:0006810| transport ABCC1;ABCG2 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCC1 40993:[DB00399 DB01058] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP3A4;CYP3A5;CYP3A7;CYP2C19 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4 40994:[DB00399 DB00332] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0055085| transmembrane transport ABCC1;SLC22A5;SLC22A4 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;SLC22A5 40995:[DB00399 DB05025] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05025|Arimoclomol SOD1 common genes common pathways GO:0042493| response to drug SOD1;ABCC1 40996:[DB00399 DB06824] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06824|Triethylenetetramine GPC1 common genes common pathways 40997:[DB00399 DB06780] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 40998:[DB00399 DB02750] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways GO:0006810| transport SLC7A8;ABCC1;SLC7A5 40999:[DB00399 DB11638] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;UGT2B7;CYP2D6;FDPS GO:0042493| response to drug LGALS1;SRP14;HNRNPD;ABCC1;LDHA GO:0006695| cholesterol biosynthetic process GGPS1;G6PD;FDPS GO:0016032| viral reproduction FDPS;HNRNPK;HSPA8;PPIA;VIM;ZYX;NPM1 GO:0006629| lipid metabolic process FDPS;CYP2D6;G6PD;UGT2B7 41000:[DB00399 DB06216] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP1A2;FDPS GO:0042493| response to drug HTR2A;DRD1;ADRA1A;DRD2;ABCC1;HTR2B;CYP1A2;HTR2C;DRD3;HTR1B 41001:[DB00399 DB07374] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways 41002:[DB00399 DB14637] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41003:[DB00399 DB00228] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0045332| phospholipid translocation KCNN4;ABCC1 GO:0042493| response to drug ABCC1;CYP2E1;GABRG3 GO:0008202| steroid metabolic process CYP2E1;FDPS GO:0006810| transport GABRB3;GABRA1;GABRG2;GABRB2;GABRA5;GABRA3;GABRA6;GABRA4;GABRB1;GABRD;ABCC1 GO:0055085| transmembrane transport KCNA1;ABCC1 41004:[DB00399 DB00663] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41005:[DB00399 DB00801] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRB2;GABRA5;GABRA3;GABRA4;GABRR1;GABRA6;GABRB1;GABRD;GABRR2;ABCC1;GABRA1;GABRB3;GABRG2 GO:0042493| response to drug ABCC1;GABRG3 41006:[DB00399 DB01282] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01282|Carbetocin OXTR common genes common pathways GO:0042493| response to drug OXTR;ABCC1 41007:[DB00399 DB00477] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00477|Chlorpromazine DRD2;DRD1;HTR1A;HTR2A;ADRA1A;ADRA1B;HRH1;KCNH2;DRD1;DRD5;DRD3;DRD4;DRD5;HTR2C;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM3;SMPD1;CALM1;ORM1;ORM2;HTR6;HTR7;HRH4;CYP2D6;CYP1A2;CYP2E1;CYP3A4;BCHE;ALB;ABCB1;ABCB11 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP1A2;CYP3A4 GO:0016032| viral reproduction HTR2A;FDPS GO:0008202| steroid metabolic process CYP2E1;CYP3A4;FDPS;CYP1A2;CYP2D6 GO:0006810| transport ABCB1;ABCB11;ABCC1 GO:0055085| transmembrane transport KCNH2;ABCB1;CALM1;ABCC1;ABCB11 GO:0042493| response to drug SMPD1;ABCC1;HTR2B;ADRA1A;DRD2;HTR2A;CYP2E1;DRD1;DRD3;ABCB1;BCHE;HTR2C;CYP1A2 41008:[DB00399 DB00226] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00226|Guanadrel SLC6A2 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCC1 GO:0006810| transport SLC6A2;ABCC1 GO:0042493| response to drug ABCC1;SLC6A2 41009:[DB00399 DB01321] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01321|Josamycin rplD;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41010:[DB00399 DB00631] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0016032| viral reproduction FDPS;POLA1 GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0042493| response to drug ABCC1;ABCG2 GO:0055085| transmembrane transport ABCG2;ABCC1 GO:0006810| transport ABCG2;ABCC1 41011:[DB00399 DB09209] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways 41012:[DB00399 DB00114] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0042493| response to drug ABAT;SRR;GAD1;ABCC1;GAD2 GO:0006629| lipid metabolic process SPTLC2;FDPS;SPTLC1;SGPL1;SPTLC3 41013:[DB00399 DB11091] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0008203| cholesterol metabolic process CAT;FDPS GO:0042493| response to drug ABCC1;CAT GO:0006629| lipid metabolic process FDPS;GPX1 41014:[DB00399 DB13179] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;NR1I2;CYP2C9;CYP2C8;CYP3A7;CYP3A5 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;NR1I2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 41015:[DB00399 DB11640] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways GO:0055085| transmembrane transport KCNA1;ABCC1 41016:[DB00399 DB00898] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0055085| transmembrane transport CACNA1D;CACNA1C;CACNA1S;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2B6;CYP2C19;CYP2E1;CYP1A1 GO:0006810| transport GABRA6;CHRNA6;GABRA4;GRIA3;CACNG2;GABRB1;GABRD;ABCC1;CACNB1;CACNG1;GABRB2;GABRA3;GABRA5;CHRNB3;GABRA1;GABRB3;GRIA4 GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 GO:0042493| response to drug ABCC1;CYP2E1;CYP1A1;GABRG3;CYP1A2 GO:0060326| cell chemotaxis ABCC1;VCAM1 GO:0016032| viral reproduction VCAM1;FDPS GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9 41017:[DB00399 DB00197] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process UGT2B7;ACSL4;PPARD;CYP3A4;PPARA;PPARG;FDPS;CYP2C9 GO:0008202| steroid metabolic process UGT1A8;CYP2C9;CYP2B6;FDPS;CYP3A4;CYP3A5;CYP1A1;UGT2B7;CYP3A7;CYP2C19;CYP2C8;UGT1A1;UGT2B15 GO:0006810| transport ABCB11;ABCC1 GO:0055085| transmembrane transport ABCC1;SLCO1B1;ABCB11 GO:0008203| cholesterol metabolic process FDPS;PPARD GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0042493| response to drug ABCC1;UGT1A1;CYP1A1;PPARG 41018:[DB00399 DB01186] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042493| response to drug HTR2A;DRD1;DRD2;ADRA1A;ABCC1;HTR2B;HTR2C;DRD3;HTR1B GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 41019:[DB00399 DB11569] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11569|Ixekizumab IL17A common genes common pathways 41020:[DB00399 DB01032] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes ABCC1 common pathways GO:0042908| xenobiotic transport ABCC3;ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCC2;SLC22A1;ABCC3;ABCC1;SLC22A2;SLC22A5 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP3A4;SLC16A1;FDPS GO:0016032| viral reproduction SLC10A1;FDPS GO:0006810| transport ABCC2;ABCC5;ABCC3;SLC10A1;ABCC1;ABCC6 GO:0008202| steroid metabolic process FDPS;CYP3A4;UGT1A1;CYP2C19;CYP2C8 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport SLCO1A2;SLC22A11;SLC22A12;ABCC1;SLC22A8;SLC22A5;SLC22A7;ABCC6;SLC22A6;SLC22A10;SLC22A2;SLC2A9;SLC22A1;SLCO1C1;ABCC2;ABCC5;ABCC11;SLC16A7;SLC16A1;ABCC4;ABCC3;PANX1;SLC10A1 GO:0099133| ABCC3;ABCC4;ABCC2;ABCC5;ABCC11;ABCC6;ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC4;ABCC2;ABCC6;SLC22A12;UGT1A1;ABCC1 GO:0060326| cell chemotaxis ABCC1 41021:[DB00399 DB01130] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41022:[DB00399 DB06634] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41023:[DB00399 DB00628] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;TSPO;ABCC1 GO:0006694| steroid biosynthetic process TSPO;FDPS GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRA3;GABRA5;GABRB2;ABCC1;GABRD;GABRB1;GABRA4;GABRA6 GO:0008202| steroid metabolic process FDPS;TSPO;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41024:[DB00399 DB09089] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CACNA1I;CACNA1G;CACNA1F;CACNA1C;CACNA1D;KCNMA1;ABCC1;CACNA1S;CACNA1H GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport CACNA1I;ABCC1;CACNB3;CACNB1;CACNB4 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0045332| phospholipid translocation KCNN4;ABCC1 41025:[DB00399 DB09570] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP3A4 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 41026:[DB00399 DB08815] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction FDPS;HTR2A GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug DRD2;HTR2A;ABCC1 41027:[DB00399 DB00400] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP1A2;FDPS GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;ABCC1 41028:[DB00399 DB01629] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01629|5-Fluorouridine SOD1 common genes common pathways GO:0042493| response to drug ABCC1;SOD1 41029:[DB00399 DB12478] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD2;ABCC1;DRD3 41030:[DB00399 DB00468] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation KCNN4;ABCC1;ABCB1 GO:0006855| drug transmembrane transport SLC22A5;SLC22A2;ABCC1;SLC22A1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9;CYP2C19;CYP2C8;CYP2E1;CYP3A7;CYP3A5;CYP1A1 GO:0055085| transmembrane transport SLC22A4;SLC22A1;ABCB1;SLCO1A2;ABCC1;SLC22A5;SLCO1B1;SLC22A2 GO:0042493| response to drug CYP2E1;CYP1A1;ABCC1;CYP1A2;ABCB1 41031:[DB00399 DB00208] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0042493| response to drug CYP1A2;CYP1A1;CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2B6;CYP2C9;FDPS;CYP1A2;CYP2C19;CYP2C8;CYP1A1;CYP2E1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 41032:[DB00399 DB00824] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0042493| response to drug ADORA2A;ABCC1 41033:[DB00399 DB11834] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11834|Guselkumab IL23A common genes common pathways 41034:[DB00399 DB08906] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1;SLCO1B1 41035:[DB00399 DB02546] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0016032| viral reproduction FDPS;HDAC1 GO:0042493| response to drug HDAC2;ABCC1;HDAC1 41036:[DB00399 DB11124] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A 41037:[DB00399 DB06587] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41038:[DB00399 DB09363] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC18A2;ABCC1;SLC6A2 GO:0042493| response to drug MAOB;SLC6A2;ABCC1 41039:[DB00399 DB00912] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C8 GO:0055085| transmembrane transport SLCO1B1;ABCB11;ABCC1;ABCC8 GO:0099133| ABCC8;ABCC1 GO:0042493| response to drug ABCC8;ABCC1;PPARG 41040:[DB00399 DB14010] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0016032| viral reproduction HTR2A;FDPS GO:0042493| response to drug ABCC1;HTR2A GO:0008202| steroid metabolic process FDPS;CYP2D6 41041:[DB00399 DB01256] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01256|Retapamulin rplC;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41042:[DB00399 DB14509] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006810| transport GRIA3;ABCC1 41043:[DB00399 DB04836] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A4;ABCC1;SLC6A2 GO:0042493| response to drug ABCC1;SLC6A2;SLC6A4 41044:[DB00399 DB00211] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006810| transport SLC15A1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC15A1 GO:0042493| response to drug ADRA1A;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6 41045:[DB00399 DB08895] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2C19 41046:[DB00399 DB14539] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP11B2;CYP11B1 GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCG2;ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5;CYP11B1;CYP3A7;CYP2C8;CYP11B2 GO:0006694| steroid biosynthetic process CYP11B1;HSD3B1;CYP11B2;FDPS GO:0042493| response to drug HSD11B2;ANXA1;ABCB1;ABCC1;ABCG2 41047:[DB00399 DB00863] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCB1;SLC22A1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP3A4 GO:0055085| transmembrane transport SLC22A8;SLC22A6;SLC22A2;ABCC1;SLC22A1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP3A5;CYP3A4;CYP2D6;CYP1A2;FDPS GO:0042493| response to drug ABCC1;BCHE;CYP1A2;ABCB1 41048:[DB00399 DB05885] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport CACNA1B;ABCC1 GO:0055085| transmembrane transport SV2A;ABCC1;CACNA1B GO:0006629| lipid metabolic process CYP3A4;FDPS 41049:[DB00399 DB11127] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0006629| lipid metabolic process GPX1;FDPS 41050:[DB00399 DB09204] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0042493| response to drug ADRA1A;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006629| lipid metabolic process FDPS;CYP2D6 41051:[DB00399 DB08826] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08826|Deferiprone UGT1A6 common genes common pathways 41052:[DB00399 DB01205] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRG2;GABRA1;GABRB3;GABRB1;GABRA4;GABRA6;ABCC1;GABRD;GABRA3;GABRA5;GABRB2 GO:0042493| response to drug GABRG3;ABCC1 41053:[DB00399 DB09185] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport ABCC1;SLC6A2 GO:0042493| response to drug CYP1A2;ABCC1;SLC6A2 GO:0006629| lipid metabolic process FDPS;CYP1A2 41054:[DB00399 DB00285] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9;CYP2B6;CYP2C19 GO:0006810| transport ABCB1;SLC6A2;ABCC1;ABCG2 GO:0055085| transmembrane transport SLC6A4;ABCB1;ABCG2;SLC6A2;ABCC1;SLC6A3 GO:0042493| response to drug ABCB1;SLC6A4;SLC6A3;ABCG2;ABCC1;SLC6A2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4 41055:[DB00399 DB06013] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06013|Aldoxorubicin TOP2A common genes common pathways 41056:[DB00399 DB14004] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0006691| leukotriene metabolic process ABCC1;CYP4A11 41057:[DB00399 DB00708] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41058:[DB00399 DB09148] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0006691| leukotriene metabolic process ABCC1;CYP4F2 GO:0008203| cholesterol metabolic process FDPS;APP 41059:[DB00399 DB00390] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0008203| cholesterol metabolic process FDPS;CYP11A1 GO:0042493| response to drug ABCC1;ATP1A1;ABCB1 GO:0006694| steroid biosynthetic process CYP11A1;FDPS GO:0006810| transport ABCC1;ABCB11;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP11A1;FDPS GO:0055085| transmembrane transport SLCO1B3;SLC51A;SLCO1C1;SLCO4C1;ABCB1;SLC22A8;ABCB11;SLCO1B1;SLCO4A1;SLCO2B1;SLCO1A2;ABCC1;SLC51B GO:0006629| lipid metabolic process CYP11A1;FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41060:[DB00399 DB00407] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 41061:[DB00399 DB00822] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB11;ABCC1 GO:0006810| transport ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP2E1;CYP3A5;FDPS;CYP3A4 GO:0042493| response to drug ABCC1;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41062:[DB00399 DB00966] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways GO:0060326| cell chemotaxis ABCC1;AGTR1 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC1;ABCG2;PPARG;ABCB1;ABCC2 GO:0055085| transmembrane transport ABCB11;ABCC1;ABCG2;ABCC2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP2C19 GO:0006810| transport ABCG2;ABCC1;ABCB11;ABCC2;ABCB1 GO:0006629| lipid metabolic process FDPS;PPARG GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 41063:[DB00399 DB05014] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0060326| cell chemotaxis ABCC1;PDGFRB GO:0042493| response to drug RET;ABCC1 GO:0016032| viral reproduction KDR;FDPS 41064:[DB00399 DB09378] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09378|Fluprednisolone CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41065:[DB00399 DB12026] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC1;ABCG2;CYP1A2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP3A4;CYP2C8 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1B3;ABCG2;ABCC1;SLCO1B1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 41066:[DB00399 DB00215] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS;CYP1A2 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug HTR2C;CYP1A2;ABCB1;SLC6A4;ADRA1A;SLC6A3;CYP2E1;ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A3;ABCC1;SLC6A2 GO:0006810| transport ABCB1;ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP2B6;CYP2D6;CYP1A2;FDPS;CYP3A4;CYP2E1;CYP2C19 41067:[DB00399 DB00250] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A5;CYP2C19;CYP2C8;FDPS;CYP2C9;CYP3A4 GO:0042493| response to drug ABCC1;PTGS2;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS;PTGS2;PTGS1 41068:[DB00399 DB00980] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP3A4;FDPS;CYP1A2;CYP2C9 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2C9 41069:[DB00399 DB00241] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug GABRG3;ABCC1 GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRB2;GABRA3;GABRA5;GABRA4;GRIK2;GABRA6;GABRB1;GABRD;ABCC1 41070:[DB00399 DB00467] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS 41071:[DB00399 DB03336] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03336|BIA COMT common genes common pathways GO:0042493| response to drug COMT;ABCC1 41072:[DB00399 DB12693] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0016032| viral reproduction HTR2A;FDPS GO:0042493| response to drug ABCC1;HTR2A GO:0008202| steroid metabolic process CYP2D6;FDPS 41073:[DB00399 DB09124] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41074:[DB00399 DB00013] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0006629| lipid metabolic process LRP2;FDPS 41075:[DB00399 DB00206] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0042493| response to drug ABCC2;ABCB1;ABCC1 GO:0099133| ABCC1;ABCC2 GO:0055085| transmembrane transport SLC18A1;SLC18A2;ABCC1;SLCO1B1;ABCB11;SLCO2B1;SLC22A2;ABCB1;ABCC2;SLC22A1 GO:0008202| steroid metabolic process CYP3A5;FDPS GO:0006810| transport ABCB1;ABCC2;ABCC1;ABCB11 GO:0006855| drug transmembrane transport SLC22A1;ABCC2;ABCB1;SLC22A2;ABCC1;SLC18A1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41076:[DB00399 DB01222] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS GO:0006810| transport ABCB11;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41077:[DB00399 DB06446] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport CACNA1A;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;HTR2A;HTR2C 41078:[DB00399 DB09383] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09383|Meprednisone CYP3A4;ALB common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41079:[DB00399 DB01403] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP2E1 GO:0042493| response to drug DRD3;HTR2C;ABCC1;DRD1;CYP2E1;HTR2A;DRD2;ADRA1A GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process FDPS;CYP2D6 41080:[DB00399 DB14009] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes ABCC1 common pathways GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0016032| viral reproduction FDPS;VDAC1;HTR2A GO:0006629| lipid metabolic process PTGS1;DAGLA;TRPV1;NAPEPLD;PTGS2;HMGCR;NAAA;CYP1A2;FDPS;CYP2C9;ALOX15;CYP2D6;CYP3A4;GPX1;PPARG;PLA2G1B GO:0034775| glutathione transmembrane transport ABCC1 GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0055085| transmembrane transport TRPV1;TRPM8;ABCG2;TRPV4;ABCC1;TRPV2;TRPV3;CACNA1H;VDAC1;CACNA1I;CACNA1G;TRPA1 GO:0008299| isoprenoid biosynthetic process HMGCR;FDPS;GGPS1 GO:0006810| transport ABCC1;ABCG2;TRPV2;TRPV1;CACNA1I GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A7;CYP1A1;CYP17A1;CYP3A5;HMGCR;CYP2C19;CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4;CYP1B1 GO:0006691| leukotriene metabolic process ALOX15;ALOX5;ABCC1 GO:0042493| response to drug CYP1A1;HTR2A;SOD1;SMPD1;ABCC1;ABCG2;PTGS2;CYP1A2;CAT;PPARG;TRPA1 GO:0099133| ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP17A1;HMGCR GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0008203| cholesterol metabolic process HMGCR;FDPS;CAT 41081:[DB00399 DB08954] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0006810| transport ABCC1;GRIN2B 41082:[DB00399 DB11338] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0016032| viral reproduction VCAM1;FDPS GO:0060326| cell chemotaxis ABCC1;VCAM1 GO:0042493| response to drug COL1A1;ABCC1 41083:[DB00399 DB00505] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways 41084:[DB00399 DB11635] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways GO:0006810| transport ABCC1;TTPA;ABCB1 GO:0008202| steroid metabolic process APOBR;NPC1L1;FDPS;CYP3A4;ABCA1 GO:0045540| regulation of cholesterol biosynthetic process FDPS;GGPS1;SEC14L2 GO:0055085| transmembrane transport ABCG8;ABCA1;ABCB1;ABCG5;ABCC1 GO:0006695| cholesterol biosynthetic process FDPS;GGPS1;NPC1L1 GO:0008203| cholesterol metabolic process ABCA1;FDPS;NPC1L1;APOBR GO:0042493| response to drug ABCG8;ABCA1;ABCB1;ABCG5;NPC1L1;ABCC1 GO:0006691| leukotriene metabolic process ABCC1;CYP4F2 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCA1;ABCC1 GO:0006855| drug transmembrane transport ABCG5;ABCC1;ABCB1 GO:0006629| lipid metabolic process TTPA;APOBR;NPC1L1;FDPS;CYP3A4;ABCA1 GO:0016032| viral reproduction SCARB1;FDPS 41085:[DB00399 DB00837] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0006810| transport GABRA1;ABCC1 41086:[DB00399 DB06785] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06785|Ganirelix GNRHR common genes common pathways 41087:[DB00399 DB13620] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways GO:0042493| response to drug ATP1A1;ABCC1 GO:0055085| transmembrane transport SLC12A1;ABCC1 GO:0006810| transport SLC12A1;ABCC1;ATP4A;FXYD2 41088:[DB00399 DB14071] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14071|Desmethylsertraline ABCB1 common genes common pathways GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41089:[DB00399 DB00381] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug ABCB1;SMPD1;ABCC1;CYP1A1 GO:0055085| transmembrane transport ABCB1;CACNA1D;CACNA1C;CACNA1B;CACNA1S;ABCC1 GO:0006810| transport CACNB1;ABCC1;CACNA1B;ABCB1 GO:0008202| steroid metabolic process CYP3A7;CYP1A1;CYP3A5;CYP2C8;FDPS;CYP2C9;CYP2B6;CYP2D6;CYP3A4;CYP2A6 41090:[DB00399 DB01173] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0042493| response to drug ABCC1;SLC6A2;CYP2E1;CYP1A2 GO:0055085| transmembrane transport SLC6A2;ABCC1;SCN10A GO:0006810| transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2B6;FDPS;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4 41091:[DB00399 DB00915] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A1 GO:0042493| response to drug DRD2;MAOB;ABCC1 GO:0055085| transmembrane transport SLC22A2;ABCC1;SLC22A1 41092:[DB00399 DB11792] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41093:[DB00399 DB01120] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0042493| response to drug ABCC1;ABCC8 GO:0099133| ABCC8;ABCC1 GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP2C9 GO:0055085| transmembrane transport ABCC1;ABCC8 GO:0006629| lipid metabolic process FDPS;CYP2C9 41094:[DB00399 DB00423] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00423|Methocarbamol CA1 common genes common pathways 41095:[DB00399 DB06726] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006629| lipid metabolic process FDPS;CYP2D6 41096:[DB00399 DB11477] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways 41097:[DB00399 DB11274] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0042493| response to drug DRD2;DRD1;ABCC1;DRD3 41098:[DB00399 DB01352] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport GABRA5;GABRA3;ABCC1;GABRA4;GABRA6;GRIK2;GABRA1 GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41099:[DB00399 DB06468] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0055085| transmembrane transport SLC9A1;ABCC1 41100:[DB00399 DB14185] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP3A5;CYP3A7 GO:0042493| response to drug HTR2C;HTR1B;DRD3;DRD1;HTR2A;ADRA1A;DRD2;ABCC1 41101:[DB00399 DB01044] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0008202| steroid metabolic process FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;ABCC1 41102:[DB00399 DB00759] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport SLC22A6;SLCO2B1;SLC22A8;SLC22A7;ABCC1;SLC22A11 GO:0006629| lipid metabolic process CYP3A4;FDPS 41103:[DB00399 DB04894] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41104:[DB00399 DB01206] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 41105:[DB00399 DB12001] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC47A2;SLC47A1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCG2;ABCC1;SLC47A2;ABCB1;SLC47A1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCG2;CDK4;ABCB1;OTC 41106:[DB00399 DB08953] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08953|Indalpine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41107:[DB00399 DB01131] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP2C19;CYP2E1 GO:0042493| response to drug CYP2E1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;CYP2D6 41108:[DB00399 DB00572] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB11 GO:0006810| transport ABCB11;ABCC1 41109:[DB00399 DB01045] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01045|Rifampicin rpoB;rpoC;NR1I2;SLCO1B1;SLCO1A2;SLCO1B3;CYP51A1;ALB;SLCO2B1;CYP2C9;CYP1A2;CYP2C8;CYP3A4;CYP2B6;UGT1A1;CYP2C19;CYP2A6;CYP2E1;CYP3A43;CYP3A7;CYP4A11;CYP2D6;ABCB1;SLCO1B3;ABCC1;SLCO2B1;ABCB11;SLCO1A2;SLC22A7;SLCO1B1;ABCC5;ABCC2;ABCC3;SLC22A6;SLC22A8 common genes ABCC1 common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2C9;CYP2B6;NR1I2;CYP2D6;CYP3A4;CYP2A6;CYP3A7;CYP2E1;CYP51A1;UGT1A1;CYP2C19;CYP2C8 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC5;ABCC2;ABCB1;ABCC3;ABCC1;ABCB11 GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;CYP51A1 GO:0055085| transmembrane transport SLCO1B3;ABCC3;ABCB1;ABCC2;ABCC5;SLC22A7;SLCO1B1;ABCB11;SLC22A8;SLCO2B1;SLC22A6;SLCO1A2;ABCC1 GO:0008203| cholesterol metabolic process CYP51A1;FDPS GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CYP51A1 GO:0099133| ABCC1;ABCC3;ABCC5;ABCC2 GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 GO:0042493| response to drug CYP1A2;ABCC2;ABCB1;CYP2E1;ABCC1;UGT1A1 GO:0006694| steroid biosynthetic process FDPS;CYP51A1 GO:0060326| cell chemotaxis ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;NR1I2;ABCC3;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCB1;ABCC3 GO:0016126| sterol biosynthetic process FDPS;CYP51A1 GO:0006629| lipid metabolic process CYP51A1;CYP2C9;CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 41110:[DB00399 DB00415] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0006810| transport ABCC1;SLC15A2;SLC15A1 GO:0055085| transmembrane transport SLC15A2;SLC22A5;ABCC1;SLC15A1;SLC16A1 GO:0006855| drug transmembrane transport ABCC1;SLC22A5 GO:0006629| lipid metabolic process SLC16A1;FDPS 41111:[DB00399 DB00312] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0042493| response to drug ABCC1;GRIN2A;GABRG3 GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0006810| transport GRIN2A;GRIN2B;GABRG2;GABRB3;GABRA1;GABRA6;GRIK2;GABRA4;GABRB1;GABRD;GRIN2C;ABCC1;GABRB2;GABRA3;GABRA5 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;NR1I2;FDPS;CYP2C19 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042908| xenobiotic transport NR1I2;ABCC1 41112:[DB00399 DB00650] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00650|Leucovorin SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC22A8 41113:[DB00399 DB08980] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08980|Fendiline CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41114:[DB00399 DB09183] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC1;ABCB5 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;FDPS;CYP2D6 GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0042493| response to drug ABCB1;ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCB5;ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB5;ABCB1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS 41115:[DB00399 DB00111] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction IL2RB;FCGR2B;FDPS 41116:[DB00399 DB01030] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0042493| response to drug TOP1;ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCC1;ABCB1;SLC47A2;SLC47A1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0016032| viral reproduction TOP1;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport SLC47A2;ABCB1;SLC47A1;ABCC1;ABCG2 41117:[DB00399 DB13933] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways 41118:[DB00399 DB01466] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug POR;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2B6;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41119:[DB00399 DB00568] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCC1;CACNA1S;CACNA1H;CACNA1C;CACNA1D;CACNA1F;CACNA1G;CACNA1I GO:0006810| transport ABCC1;CACNA1I GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2B6;FDPS;CYP1A2;CYP3A4;CYP2A6;CYP1A1 GO:0042493| response to drug ABCC1;CYP1A1;DRD2;DRD1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6 41120:[DB00399 DB01053] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLC22A4;SLC15A1;ABCC1;SLCO3A1;SLC22A11;SLC22A6;SLCO2B1;SLCO1B1;SLC22A8;SLC15A2;SLC22A5;SLCO4A1 GO:0006810| transport SLC15A1;ABCC1;SLC15A2 GO:0006855| drug transmembrane transport SLC22A5;ABCC1 41121:[DB00399 DB03907] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways GO:0042493| response to drug COMT;ABCC1 41122:[DB00399 DB01085] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2E1;FDPS;CYP3A4;CYP2A6 GO:0006629| lipid metabolic process CYP3A4;FDPS 41123:[DB00399 DB00227] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCB1 GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0006629| lipid metabolic process UGT2B7;HMGCR;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;UGT2B7;CYP3A7;CYP2C8;UGT1A1;HMGCR;CYP2D6;CYP2C9;FDPS;CYP3A4 GO:0006810| transport ABCC2;ABCB1;ABCB11;ABCC1 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;FDPS;GGPS1 GO:0055085| transmembrane transport ABCB1;ABCC2;ABCC1;SLCO1A2;ABCB11;SLCO1B1 GO:0008299| isoprenoid biosynthetic process HMGCR;FDPS;GGPS1 GO:0008203| cholesterol metabolic process FDPS;HMGCR GO:0006695| cholesterol biosynthetic process HMGCR;FDPS;GGPS1 GO:0042493| response to drug HDAC2;ABCC1;UGT1A1;ABCC2;ABCB1 GO:0099133| ABCC1;ABCC2 GO:0006694| steroid biosynthetic process FDPS;HMGCR 41124:[DB00399 DB01645] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes ABCC1 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS;CYP1A2 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport NR1I2;ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0099133| ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC1;ABCG2;PTK2B;ABCB1;CYP1A2 GO:0060326| cell chemotaxis ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;FDPS;NR1I2;CYP2C9;CYP3A4;CYP1B1 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCG2;ABCC1;ABCB1;TTR GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC1;SLCO2B1;SLCO1B1 41125:[DB00399 DB00883] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2E1 GO:0042493| response to drug ABCC1;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41126:[DB00399 DB01033] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0099133| ABCC4;ABCC5;ABCC1 GO:0042493| response to drug ABCC1;PPAT;ABCC4 GO:0055085| transmembrane transport ABCC5;ABCC4;ABCC1;SLC22A8 GO:0006810| transport ABCC1;ABCC5 41127:[DB00399 DB06372] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways GO:0006629| lipid metabolic process FDPS;IL1RN 41128:[DB00399 DB08814] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0006629| lipid metabolic process PTGS1;FDPS 41129:[DB00399 DB00365] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes ABCC1 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0099039| ABCC1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1;SLC22A2;SLC22A5 GO:0060326| cell chemotaxis ABCC1 GO:0042493| response to drug ABCC1;CYP1A2;ABCC2;ABCB1 GO:0006691| leukotriene metabolic process ABCC1 GO:0099133| ABCC1;ABCC2 GO:0006810| transport ABCB1;ABCC2;ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2 GO:0055085| transmembrane transport ABCC2;ABCB1;SLC22A6;SLC22A2;SLC22A5;ABCC1 41130:[DB00399 DB11619] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006810| transport AR;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 41131:[DB00399 DB09272] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0006810| transport ABCC1;ABCC2 GO:0055085| transmembrane transport ABCC1;SLC22A8;SLCO1B1;ABCC2 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC1;ABCC2 GO:0006855| drug transmembrane transport ABCC2;ABCC1 41132:[DB00399 DB04871] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;ABCC1;HTR2C;CYP1A2 GO:0008202| steroid metabolic process CYP2C19;CYP1A1;CYP3A4;CYP2A6;CYP2B6;CYP2D6;CYP1A2;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6 41133:[DB00399 DB00294] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41134:[DB00399 DB00657] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways 41135:[DB00399 DB01182] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6 GO:0055085| transmembrane transport ABCB1;KCNH2;ABCC1;SCN5A GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP1A2;FDPS;CYP2C8 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1 41136:[DB00399 DB01104] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01104|Sertraline SLC6A4;SLC6A3;PGRMC1;SIGMAR1;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP2B6;MAOB;MAOA;CYP2B;ALB;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC6A3;SLC6A4;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2B6;CYP2C9;CYP2C19 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;SLC6A3;MAOB;ABCB1;SLC6A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;CYP2D6 41137:[DB00399 DB00810] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process CYP2D6;FDPS 41138:[DB00399 DB01018] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;FDPS 41139:[DB00399 DB05361] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05361|SR-123781A SERPINC1;F2R common genes common pathways 41140:[DB00399 DB01409] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0055085| transmembrane transport SLC22A5;ABCC1;SLC22A4 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0006855| drug transmembrane transport SLC22A5;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41141:[DB00399 DB00865] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2B6;FDPS GO:0055085| transmembrane transport SLC6A3;ABCC1;SLC18A2 GO:0042493| response to drug POR;ABCC1;SLC6A3;ADRA1A GO:0006629| lipid metabolic process FDPS;CYP3A4 41142:[DB00399 DB13941] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2C19;FDPS;CYP2B6;CYP2C9;CYP3A4 GO:0042493| response to drug CYP2E1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 41143:[DB00399 DB00764] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2C8 GO:0006629| lipid metabolic process FDPS;CYP3A4 41144:[DB00399 DB00694] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes ABCC1 common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCG2;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0060326| cell chemotaxis ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC2;ABCB1;POR;ABCC1;ABCG2;CYP1A1;ABCC6 GO:0099133| ABCC2;ABCC1;ABCC6;ABCC10 GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB11;ABCC10;ABCC6;ABCC2;ABCB1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1B1;CYP3A4;CYP1A1;CYP3A5 GO:0006810| transport ABCG2;ABCC1;ABCC6;ABCB11;ABCC2;ABCB1 41145:[DB00399 DB00189] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRG2;GABRA1;GABRB3;ABCC1;GABRD;GABRB1;GABRA6;GABRA4;GABRA5;GABRA3;GABRB2 GO:0042493| response to drug GABRG3;ABCC1 41146:[DB00399 DB09395] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09395|Sodium acetate ACSS2 common genes common pathways 41147:[DB00399 DB01366] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01366|Procaterol ADRB2 common genes common pathways 41148:[DB00399 DB00385] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00385|Valrubicin TOP2A common genes common pathways 41149:[DB00399 DB14596] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0008203| cholesterol metabolic process FDPS;PON1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;PON1 41150:[DB00399 DB01656] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41151:[DB00399 DB01440] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A1;SLC16A7;ABCC1;SLC16A3 GO:0006810| transport GABRB1;ABCC1 GO:0006629| lipid metabolic process SLC16A1;FDPS 41152:[DB00399 DB08874] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41153:[DB00399 DB13036] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13036|Ramatroban PTGDR2 common genes common pathways 41154:[DB00399 DB01144] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 41155:[DB00399 DB01623] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP1A2;FDPS GO:0055085| transmembrane transport ABCC1;SLC22A1 GO:0042493| response to drug CYP1A2;DRD1;HTR2A;DRD2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;SLC22A1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6 GO:0016032| viral reproduction HTR2A;FDPS 41156:[DB00399 DB00033] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways 41157:[DB00399 DB00857] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP11A1;CYP2D6;CYP2C9;CYP3A4;PTGS1 GO:0016126| sterol biosynthetic process SQLE;FDPS GO:0006695| cholesterol biosynthetic process FDPS;SQLE;GGPS1 GO:0008203| cholesterol metabolic process FDPS;SQLE;CYP11A1 GO:0006694| steroid biosynthetic process FDPS;CYP11A1;CYP19A1 GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP11A1;CYP3A4;CYP2C8;CYP2C19 GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;SQLE 41158:[DB00399 DB04829] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug HTR2B;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS 41159:[DB00399 DB13997] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways GO:0055085| transmembrane transport ABCB5;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB5 GO:0042908| xenobiotic transport ABCB5;ABCC1 41160:[DB00399 DB01083] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FASN;FDPS;PNLIP;PLA2G4A;LIPF GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0045540| regulation of cholesterol biosynthetic process FDPS;GGPS1;FASN 41161:[DB00399 DB00691] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways GO:0016032| viral reproduction FDPS;ACE2 GO:0055085| transmembrane transport ABCC1;SLC15A2;SLC15A1 GO:0006810| transport SLC15A1;SLC15A2;ABCC1 41162:[DB00399 DB05442] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05442|Etiprednol dicloacetate IL1B common genes common pathways 41163:[DB00399 DB09060] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug ABCC2;ABCC1 GO:0006810| transport ABCC1;ABCC2 GO:0055085| transmembrane transport ABCC2;SLC22A8;ABCC1 GO:0006855| drug transmembrane transport ABCC2;ABCC1 41164:[DB00399 DB00434] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0016032| viral reproduction HTR2A;FDPS GO:0042493| response to drug ABCC1;HTR2A;HTR2C 41165:[DB00399 DB00949] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0008202| steroid metabolic process CYP2C19;CYP2E1;CYP3A4;FDPS;CYP2C9 GO:0006810| transport ABCC1;GRIN2B;GRIN2A GO:0042493| response to drug GRIN2A;CYP2E1;ABCC1 41166:[DB00399 DB08912] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP2B6;CYP2C9;FDPS;CYP3A4 GO:0055085| transmembrane transport SLC22A6;SLC22A8;SLCO1B1;ABCC1;ABCG2;SLCO1B3;ABCB1 GO:0042493| response to drug ABCB1;ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 41167:[DB00399 DB09258] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways 41168:[DB00399 DB09046] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09046|Metreleptin LEPR common genes common pathways GO:0008203| cholesterol metabolic process LEPR;FDPS 41169:[DB00399 DB05936] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05936|CVT-6883 ADORA2B common genes common pathways 41170:[DB00399 DB00347] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP3A4;CYP2E1;CYP2C19;CYP2C8 GO:0055085| transmembrane transport CACNA1G;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 41171:[DB00399 DB11755] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0042493| response to drug TRPA1;ABCC1 GO:0006810| transport TRPV2;ABCC1 GO:0055085| transmembrane transport TRPV2;ABCC1;TRPM8;TRPA1 41172:[DB00399 DB00378] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41173:[DB00399 DB01005] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process CYP2D6;FDPS 41174:[DB00399 DB08918] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4;CYP2C19;CYP2C8 GO:0006810| transport SLC6A2;ABCC1;ABCB1 GO:0055085| transmembrane transport SLC6A4;ABCB1;SLC6A2;ABCC1 GO:0042493| response to drug ABCB1;SLC6A4;ABCC1;SLC6A2 41175:[DB00399 DB13168] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006691| leukotriene metabolic process ALOX5;ABCC1 GO:0006629| lipid metabolic process FADS1;FDPS;PTGS2;FADS2 41176:[DB00399 DB03066] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A3;ABCC1;SLC16A7;SLC16A1 GO:0006629| lipid metabolic process FDPS;SLC16A1 41177:[DB00399 DB01170] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCC1 GO:0042493| response to drug ABCC1;SLC6A2 41178:[DB00399 DB00029] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 41179:[DB00399 DB03023] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0042493| response to drug LCK;ABCC1;SRC;LYN GO:0016032| viral reproduction LCK;SRC;LYN;FDPS 41180:[DB00399 DB11779] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11779|Danoprevir CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41181:[DB00399 DB00550] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP1A1 GO:0042493| response to drug ABCC1;CYP1A1 41182:[DB00399 DB06419] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41183:[DB00399 DB11960] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41184:[DB00399 DB09052] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09052|Blinatumomab CD19;CD3D common genes common pathways 41185:[DB00399 DB08834] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCC1 41186:[DB00399 DB01129] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0042493| response to drug CYP1A2;ABCC1;ABCG2;CYP1A1 GO:0006810| transport ABCG2;ABCC1;ATP4A GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;FDPS;CYP2C19;CYP2C8;CYP1A1 GO:0055085| transmembrane transport ABCG2;ABCC1 41187:[DB00399 DB12489] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41188:[DB00399 DB00698] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways GO:0006810| transport ABCG2;ABCC1;ABCB11 GO:0055085| transmembrane transport ABCG2;ABCC1;ABCB11 GO:0042493| response to drug POR;ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCG2;ABCC1 41189:[DB00399 DB01261] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport SLC22A8;ABCC1;ABCB1 41190:[DB00399 DB00145] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0042493| response to drug ABCC1;GRIN2A GO:0055085| transmembrane transport SLC36A1;SLC6A9;ABCC1;SLC6A5;SLC16A10 GO:0006810| transport GRIN2A;GRIN2C;ABCC1;SLC6A5;SLC6A9 GO:0006629| lipid metabolic process BAAT;FDPS 41191:[DB00399 DB08892] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways GO:0055085| transmembrane transport SLC16A1;ABCC1 GO:0006629| lipid metabolic process FDPS;SLC16A1 41192:[DB00399 DB00830] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways GO:0042493| response to drug SLC6A3;SLC6A2;ABCC1 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A3;SLC6A2;ABCC1 41193:[DB00399 DB11805] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11805|Saracatinib CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41194:[DB00399 DB01708] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0008203| cholesterol metabolic process FDPS;SULT2B1 GO:0042493| response to drug GRIN2A;GABRG3;ABCC1 GO:0006694| steroid biosynthetic process FDPS;HSD17B1 GO:0008202| steroid metabolic process CYP3A7;NR1I2;FDPS;SULT2B1;SULT2A1;CYP3A4 GO:0006810| transport GRIN2A;GRIN2B;GABRG2;GABRB3;GABRA1;GABRD;ABCC1;GRIN2C;GABRA4;GABRA6;GABRB1;GABRB2;GABRA5;GABRA3;AR GO:0006629| lipid metabolic process SULT2A1;CYP3A4;PPARA;FDPS;SULT2B1;HSD17B1 GO:0042908| xenobiotic transport ABCC1;NR1I2 41195:[DB00399 DB01108] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006694| steroid biosynthetic process FDPS;HSD3B1;HSD3B2 41196:[DB00399 DB04861] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 41197:[DB00399 DB12243] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCC1 41198:[DB00399 DB09198] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process PPARG;CYP3A4;CYP2C9;CYP1A2;FDPS GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;CYP1A2;ABCB1;PPARG GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP1A2;FDPS;CYP2C8;CYP2C19 GO:0055085| transmembrane transport SLCO1B1;ABCC1;SLCO3A1;ABCB1 41199:[DB00399 DB05449] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05449|FM-VP4 ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41200:[DB00399 DB06733] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06733|Bafilomycin A1 ATP6V1A common genes common pathways GO:0006810| transport ATP6V1A;ABCC1 41201:[DB00399 DB02056] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLCO2A1 GO:0008202| steroid metabolic process AKR1C3;FDPS 41202:[DB00399 DB01294] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 41203:[DB00399 DB04821] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways GO:0042493| response to drug ABCC1;SLC6A2;MAOB;SLC6A3;SLC6A4 GO:0055085| transmembrane transport SLC6A4;SLC6A3;SLC18A2;SLC6A2;ABCC1 GO:0006810| transport SLC6A2;ABCC1 41204:[DB00399 DB00193] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2B6;UGT1A1 GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A4 GO:0042493| response to drug HTR2C;SLC6A4;ABCC1;SLC6A2;UGT1A1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41205:[DB00399 DB01022] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 41206:[DB00399 DB04576] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ABCC1 41207:[DB00399 DB02337] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 41208:[DB00399 DB04877] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04877|Voacamine ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 41209:[DB00399 DB00611] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways 41210:[DB00399 DB02105] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02105|3,5-Dinitrocatechol COMT common genes common pathways GO:0042493| response to drug COMT;ABCC1 41211:[DB00399 DB09072] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways 41212:[DB00399 DB03203] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0016032| viral reproduction FDPS;PVR GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 41213:[DB00399 DB13988] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13988|SB-269970 HTR7 common genes common pathways 41214:[DB00399 DB00726] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00726|Trimipramine SLC6A4;SLC6A2;SLC6A3;HTR2A;HTR1A;ADRA1A;ADRA1B;DRD2;ADRA2B;HRH1;HTR2C;HTR3A;HTR1D;ADRA2A;DRD1;DRD5;ADRB1;ADRB2;ADRB3;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A3;ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4;CYP2C19 GO:0006810| transport ABCB1;ABCC1;SLC6A2 GO:0042493| response to drug ABCC1;SLC6A2;ADRA1A;DRD2;SLC6A3;HTR2A;DRD1;ABCB1;SLC6A4;HTR2C 41215:[DB00399 DB00745] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2B6;CYP2C19;CYP3A5 GO:0055085| transmembrane transport ABCC1;SLC6A3 GO:0042493| response to drug CYP1A2;ABCC1;SLC6A3 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9 41216:[DB00399 DB06770] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;ABCC1;CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP2C8;CYP1A1;CYP2E1;CYP2D6;FDPS;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP1A2 41217:[DB00399 DB01234] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP11A1;CYP2D6;CYP3A4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;NR1I2;ABCB1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCG2;ABCC1 GO:0008203| cholesterol metabolic process CYP11A1;FDPS GO:0006694| steroid biosynthetic process CYP17A1;NR0B1;CYP11A1;FDPS;CYP19A1 GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 GO:0042493| response to drug CYP2E1;CYP1A1;ABCG2;ABCC1;ANXA1;ABCC2;ABCB1 GO:0099133| ABCC2;ABCC1 GO:0008202| steroid metabolic process CYP1B1;CYP2A6;CYP3A4;CYP2D6;CYP2B6;NR1I2;FDPS;CYP11A1;CYP2C8;CYP2C19;CYP17A1;CYP3A5;CYP1A1;CYP3A7;CYP2E1 GO:0006810| transport ABCB1;ABCC2;ABCB11;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC2;ABCG2;ABCC1;SLCO1A2;ABCB11 41218:[DB00399 DB00779] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCC1 41219:[DB00399 DB01016] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes ABCC1 common pathways GO:0060326| cell chemotaxis ABCC1 GO:0042493| response to drug ABCB1;ABCC2;ABCA1;CPT1A;ABCG2;ABCC1;ABCC9;KCNJ11;ABCC8 GO:0006691| leukotriene metabolic process ABCC1 GO:0099133| ABCC2;ABCC3;ABCC9;ABCC1;ABCC8;CFTR GO:0008203| cholesterol metabolic process ABCA1;FDPS GO:0006695| cholesterol biosynthetic process CFTR;FDPS;GGPS1 GO:0055085| transmembrane transport ABCB11;SLC15A2;SLC22A7;SLC22A6;CFTR;SLCO2B1;KCNJ11;ABCC8;SLCO1A2;ABCC9;ABCC1;ABCG2;SLC15A1;ABCC3;ABCA1;ABCC2;ABCB1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP2C9;FDPS;ABCA1;CYP3A4;CYP2C19 GO:0006810| transport SLC15A1;ABCC3;ABCC2;ABCB1;SLC15A2;ABCB11;ABCG2;ABCC1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CPT1A;FDPS;CYP2C9;CYP3A4;ABCA1 GO:0006855| drug transmembrane transport ABCC3;ABCC2;ABCB1;ABCG2;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1;ABCA1 GO:0099039| ABCC1 GO:0042908| xenobiotic transport ABCC3;ABCB1;ABCC1;ABCG2 41220:[DB00399 DB05928] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC3;ABCB1;ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCC3;NR1I2;ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;UGT2B7 GO:0055085| transmembrane transport SLCO2B1;SLCO1B1;ABCC1;ABCG2;ABCC3;SLCO1B3;ABCB1 GO:0006810| transport ABCB1;ABCC3;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP1A1;UGT2B7;CYP2C19;NR1I2;CYP1A2;FDPS;CYP3A4 GO:0099133| ABCC3;ABCC1 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1;ABCG2;CYP1A1 41221:[DB00399 DB13952] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A2;ABCB1;SLC22A1;SLC22A3 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;NR1I2;ABCB1 GO:0016032| viral reproduction FDPS;BECN1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;HSD17B2;CYP3A4 GO:0055085| transmembrane transport SLCO1B1;ABCC10;SLC22A8;SLCO4A1;SLCO2B1;SLC22A2;SLCO1A2;SLC22A11;ABCC1;ABCG2;SLCO1B3;SLC22A3;SLCO1C1;SLC22A1;ABCB1 GO:0008202| steroid metabolic process CYP2C9;NR1I2;FDPS;CYP1A2;CYP1B1;CYP3A4;CYP3A5;CYP1A1;CYP3A7;CYP2C19;CYP2C8;UGT1A1 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0006694| steroid biosynthetic process HSD17B2;FDPS GO:0099133| ABCC10;ABCC1 GO:0042493| response to drug ABCG2;UGT1A1;ABCC1;BECN1;CYP1A1;ABCB1;CYP1A2 41222:[DB00399 DB06704] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06704|Iobenguane SLC6A2 common genes common pathways GO:0042493| response to drug SLC6A2;ABCC1 GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A2;ABCC1 41223:[DB00399 DB00142] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0006629| lipid metabolic process FDPS;SLC16A1 GO:0042493| response to drug SLC1A3;SLC1A2;PFAS;GAD1;ABAT;GRIN2A;GCLM;ABCC1;GAD2 GO:0006810| transport GRIK4;GRIN2A;GRIN2B;GRIA4;GRIN2C;ABCC1;GRIK1;GRIA3;GRIK2;GRID2 GO:0055085| transmembrane transport SLC25A18;GRIK3;ABCC1;GRIK1;GRIK2;GRIK5;SLC1A7;GRIK4;SLC25A22;SLC16A10;SLC16A1 41224:[DB00399 DB00439] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;HMGCR GO:0045540| regulation of cholesterol biosynthetic process HMGCR;FDPS;GGPS1 GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB11;SLCO1B1;ABCC2;ABCB1 GO:0008299| isoprenoid biosynthetic process HMGCR;GGPS1;FDPS GO:0008202| steroid metabolic process CYP2C8;UGT1A1;HMGCR;CYP3A5;CYP3A7;CYP3A4;CYP2D6;CYP2B6;CYP2C9;FDPS GO:0006810| transport ABCB11;ABCG2;ABCC1;ABCC2;ABCB1 GO:0042493| response to drug ABCB1;ABCC2;ABCG2;UGT1A1;ABCC1 GO:0099133| ABCC1;ABCC2 GO:0006694| steroid biosynthetic process FDPS;HMGCR GO:0008203| cholesterol metabolic process HMGCR;FDPS GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1;FDPS 41225:[DB00399 DB00593] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP2E1;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;CACNA1G GO:0042493| response to drug CYP2E1;ABCC1 41226:[DB00399 DB00508] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0042493| response to drug HTR2B;ABCC1;DRD1;DRD2;ABCB1;BCHE GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 41227:[DB00399 DB06594] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2C9 GO:0042493| response to drug ABCC1;HTR2C;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2C9 41228:[DB00399 DB00486] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0042493| response to drug ABCC1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C8;CYP2C9;FDPS GO:0006629| lipid metabolic process FDPS;CYP2C9 41229:[DB00399 DB05120] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05120|AT1391 INSR common genes common pathways 41230:[DB00399 DB09207] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0042493| response to drug DRD3;ABCC1;DRD2 41231:[DB00399 DB00198] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CES1 GO:0042493| response to drug ABCC4;ABCC1 GO:0099133| ABCC1;ABCC4 GO:0006810| transport SLC15A1;ABCC1 GO:0055085| transmembrane transport ABCC4;SLC15A1;ABCC1;SLC22A8 GO:0006629| lipid metabolic process FDPS;NEU2;NEU1 41232:[DB00399 DB00188] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6;CYP2C19 GO:0055085| transmembrane transport PSMB5;PSMB1;ABCC1 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 GO:0016032| viral reproduction PSMB5;FDPS;PSMB1 41233:[DB00399 DB08871] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;BCL2 GO:0042493| response to drug ABCC1;BCL2 41234:[DB00399 DB00304] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41235:[DB00399 DB09223] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0042493| response to drug DRD2;HTR2A;ABCC1;DRD3 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process FDPS;CYP3A4 41236:[DB00399 DB01106] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01106|Levocabastine HRH1;NTSR2 common genes common pathways 41237:[DB00399 DB01210] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006629| lipid metabolic process CYP2D6;FDPS 41238:[DB00399 DB06217] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0055085| transmembrane transport KCNA5;ABCC1;SCN5A;KCND3;KCNH2 GO:0008202| steroid metabolic process CYP2D6;FDPS 41239:[DB00399 DB02377] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02377|Guanine PNP;gpt;GCH1 common genes common pathways GO:0042493| response to drug ABCC1;PNP 41240:[DB00399 DB01174] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01174|Phenobarbital GABRA1;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP2C19;CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2;CYP2A6;CYP2E1;CYP3A5;CYP4A11;CYP1A1;CYP1B1;CYP2C18;CYP3A7;CYP4B1;UGT1A1;UGT2B7;ABCB1;ABCC3;ABCB11;ABCC1;SLCO2A1;ABCC2 common genes ABCC1 common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS;CYP1A2;UGT2B7 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCC3;ABCB1;ABCC2 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1;NR1I2;ABCC3 GO:0060326| cell chemotaxis ABCC1 GO:0099133| ABCC1;ABCC2;ABCC3 GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 GO:0042493| response to drug CYP1A2;ABCC2;ABCB1;GRIN2A;CYP1A1;CYP2E1;UGT1A1;ABCC1 GO:0055085| transmembrane transport SLCO2A1;ABCC1;GRIK2;ABCB11;ABCB1;ABCC2;ABCC3 GO:0008202| steroid metabolic process CYP1B1;CYP2A6;CYP3A4;NR1I2;CYP2B6;CYP2C9;CYP1A2;FDPS;UGT1A1;CYP2C19;CYP2C8;CYP1A1;CYP3A5;CYP3A7;CYP2E1;UGT2B7 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC3;GABRA1;ABCC2;ABCB1;GRIN2A;GRIN2B;ABCB11;GRIN2C;ABCC1;GRIK2 41241:[DB00399 DB08992] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08992|Eperisone CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41242:[DB00399 DB11251] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0045540| regulation of cholesterol biosynthetic process FDPS;SEC14L2;GGPS1 GO:0008202| steroid metabolic process CYP3A4;FDPS;VLDLR;LDLR;APOBR GO:0006810| transport ABCB1;ABCC1;TTPA GO:0006691| leukotriene metabolic process CYP4F2;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0008203| cholesterol metabolic process FDPS;VLDLR;LDLR;APOBR GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0016032| viral reproduction SCARB1;LDLR;FDPS GO:0006629| lipid metabolic process TTPA;LDLR;APOBR;VLDLR;FDPS;CYP3A4 41243:[DB00399 DB00973] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0042493| response to drug ABCG8;ABCB1;ABCC2;ABCG5;NPC1L1;ABCG2;ABCC1;UGT1A1 GO:0099133| ABCC3;ABCC2;ABCC1 GO:0008203| cholesterol metabolic process FDPS;NPC1L1;SOAT1 GO:0006695| cholesterol biosynthetic process FDPS;GGPS1;NPC1L1 GO:0055085| transmembrane transport SLCO1B1;ABCB11;ABCC1;ABCG5;ABCG2;ABCC3;ABCG8;ABCB1;ABCC2 GO:0008202| steroid metabolic process SOAT1;UGT1A1;UGT2B15;NPC1L1;CYP2C8;UGT2B7;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC2;ABCC3;ABCG2;ABCC1;ABCB11 GO:0016032| viral reproduction FDPS;ANPEP GO:0006629| lipid metabolic process CYP3A4;FDPS;SOAT1;NPC1L1;UGT2B7 GO:0006855| drug transmembrane transport ABCC3;ABCB1;ABCC2;ABCG5;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC3;ABCC1;ABCG2 41244:[DB00399 DB01577] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0006855| drug transmembrane transport SLC22A3;SLC22A5;SLC18A1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC22A5;SLC6A3;SLC18A2;SLC18A1;SLC6A2;ABCC1;SLC22A3;SLC6A4 GO:0042493| response to drug SLC6A4;SLC6A3;MAOB;ABCC1;SLC6A2 41245:[DB00399 DB09330] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 GO:0042493| response to drug ABCG2;ABCC1;ABCB1;CYP1A2 GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB1 41246:[DB00399 DB05740] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways 41247:[DB00399 DB00451] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00451|Levothyroxine THRA;THRB;CYP2C8;UGT1A1;TTR;SERPINA7;ALB;SLCO1C1;SLC16A2;ABCB1;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4A1;SLCO4C1;SLC7A5;SLCO2B1 common genes common pathways GO:0006810| transport ABCC1;SLC16A2;TTR;ABCB1;SLC7A5 GO:0008202| steroid metabolic process FDPS;CYP2C8;UGT1A1 GO:0055085| transmembrane transport SLCO1A2;ABCC1;SLCO1B1;SLCO4A1;SLCO2B1;SLCO1C1;ABCB1;SLCO4C1;SLCO1B3;SLC16A2 GO:0042493| response to drug ABCB1;ABCC1;UGT1A1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41248:[DB00399 DB06362] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06362|Becatecarin TOP2A;TOP2B common genes common pathways 41249:[DB00399 DB03052] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03052|Dazoxiben TBXAS1 common genes common pathways GO:0006629| lipid metabolic process TBXAS1;FDPS 41250:[DB00399 DB00473] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCC1;SCN10A 41251:[DB00399 DB00441] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug TYMS;ABCC1;ABCB1 GO:0099133| ABCC10;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1;ABCC10 41252:[DB00399 DB01046] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways GO:0006810| transport CLCN2;ABCC1 GO:0055085| transmembrane transport CLCN2;ABCC1 41253:[DB00399 DB00235] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00235|Milrinone PDE3A common genes common pathways GO:0006629| lipid metabolic process PDE3A;FDPS GO:0042493| response to drug ABCC1;PDE3A 41254:[DB00399 DB00540] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2D6;CYP3A4;PTGS1 GO:0016032| viral reproduction HTR2A;FDPS GO:0042493| response to drug HTR2A;CYP2E1;DRD2;ADRA1A;ABCC1;SLC6A2;CYP1A2;HTR2C;SLC6A4 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP2C19;CYP2D6;FDPS;CYP1A2;CYP3A4 GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A4 41255:[DB00399 DB05015] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;HDAC2;HDAC1;ABCB1;HDAC5;HDAC4;CYP1A2 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP1A2;CYP2C8 GO:0006810| transport ABCC1;ABCB1 GO:0016032| viral reproduction HDAC1;FDPS GO:0006629| lipid metabolic process CYP2C9;CYP1A2;FDPS GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41256:[DB00399 DB01396] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP11A1;FDPS;CYP3A4 GO:0055085| transmembrane transport SLCO1A2;ABCC1;ABCB1;SLCO4C1 GO:0008202| steroid metabolic process CYP3A4;CYP11A1;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ATP1A1;ABCB1 GO:0006694| steroid biosynthetic process CYP11A1;FDPS GO:0008203| cholesterol metabolic process CYP11A1;FDPS 41257:[DB00399 DB06717] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP3A4 41258:[DB00399 DB03619] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0016032| viral reproduction SLC10A1;FDPS GO:0006810| transport SLC10A1;SLC10A2;ABCC1;ABCB11 GO:0055085| transmembrane transport SLCO1A2;ABCC1;ABCB11;SLC10A2;SLC10A1 41259:[DB00399 DB00404] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 GO:0042493| response to drug GABRG3;ABCC1 GO:0006810| transport GABRA3;GABRA5;GABRB2;ABCC1;GABRD;GABRB1;GABRA4;GABRA6;GABRB3;GABRA1;GABRG2 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP2C9;FDPS;CYP3A4 41260:[DB00399 DB01407] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0008202| steroid metabolic process CYP1A1;FDPS GO:0042493| response to drug CYP1A1;ABCC1 41261:[DB00399 DB01439] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 41262:[DB00399 DB00072] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0016032| viral reproduction FDPS;FCGR2B GO:0006694| steroid biosynthetic process CYP19A1;FDPS 41263:[DB00399 DB00959] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 41264:[DB00399 DB01411] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug ABCC1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP3A4 GO:0006810| transport ABCC1;ABCC2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0006855| drug transmembrane transport ABCC2;ABCC1 41265:[DB00399 DB00041] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1;PTGS2 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2E1 GO:0006629| lipid metabolic process FDPS;PLA2G4A;CYP3A4;PTGS2 GO:0016032| viral reproduction IL2RB;FDPS;IL2RG 41266:[DB00399 DB13146] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC4;ABCC1 GO:0006810| transport ABCB1;GRIN2A;GRIN2B;GRIA4;GRIN2C;ABCC1;GRIA3;SLC7A7 GO:0042493| response to drug ABCC4;ABCB1;GRIN2A;ABCC1 GO:0099133| ABCC4;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0016032| viral reproduction SLC1A5;FDPS 41267:[DB00399 DB09555] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0055085| transmembrane transport SLC22A1;ABCC1;SLC22A2 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A1 41268:[DB00399 DB01429] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0055085| transmembrane transport CALM1;SCN5A;ABCC1 41269:[DB00399 DB09338] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways GO:0055085| transmembrane transport SLC16A1;AQP1;ABCC1 GO:0042493| response to drug ABCC1;AQP1 GO:0006629| lipid metabolic process PCK1;SLC16A1;FDPS 41270:[DB00399 DB00379] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2B6;CYP2E1 GO:0042493| response to drug CYP2E1;ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6 41271:[DB00399 DB09418] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways GO:0006810| transport SLC5A5;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC5A5 41272:[DB00399 DB00526] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0055085| transmembrane transport SLC22A3;ABCC2;SLC22A2;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP1B1;FDPS;CYP2E1;CYP1A1 GO:0006810| transport ABCC2;ABCG2;ABCC1 GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug ABCC2;CYP1A1;SOD1;CYP2E1;ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A2;SLC31A1;ABCC2;SLC22A3 GO:0042908| xenobiotic transport ABCC1;ABCG2 41273:[DB00399 DB01127] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCC1;CYP2E1 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0008202| steroid metabolic process NR1I2;FDPS;CYP3A4;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042908| xenobiotic transport NR1I2;ABCC1 41274:[DB00399 DB12952] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12952|Methylprednisone CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41275:[DB00399 DB00380] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways 41276:[DB00399 DB00195] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ABCC1 41277:[DB00399 DB01363] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0042493| response to drug SLC6A4;SLC6A2;ABCC1;SLC6A3;MAOB GO:0055085| transmembrane transport ABCC1;SLC6A2;SLC18A2;SLC18A1;SLC6A3;SLC6A4 GO:0006810| transport ABCC1;SLC6A2 GO:0006855| drug transmembrane transport ABCC1;SLC18A1 41278:[DB00399 DB00499] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2 GO:0006810| transport ABCC1;AR GO:0008202| steroid metabolic process CYP3A4;CYP1B1;CYP1A2;FDPS;NR1I2;CYP2C19;CYP1A1;CYP3A5 GO:0042493| response to drug CYP1A2;ABCC1;CYP1A1 41279:[DB00399 DB14540] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP11B2;CYP2C8;CYP3A7;CYP11B1;CYP3A5 GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1A2;ABCG2;ABCC1;SLC22A8 GO:0042493| response to drug ANXA1;HSD11B2;ABCB1;ABCG2;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP11B2;CYP11B1;HSD3B1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4;CYP11B1;CYP11B2 41280:[DB00399 DB01369] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41281:[DB00399 DB00474] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways GO:0006810| transport GABRA1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2C19 41282:[DB00399 DB13953] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0055085| transmembrane transport SLC22A3;SLCO1B3;SLC22A1;SLCO1C1;ABCB1;SLCO1B1;ABCC10;SLC22A8;SLCO4A1;SLCO2B1;SLC22A2;SLCO1A2;SLC22A11;ABCC1;ABCG2 GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;UGT1A1;CYP3A5;CYP1A1;CYP3A7;CYP1B1;CYP3A4;NR1I2;CYP2C9;FDPS;CYP1A2 GO:0006694| steroid biosynthetic process HSD17B2;FDPS GO:0042493| response to drug ABCB1;CYP1A2;ABCG2;UGT1A1;ABCC1;CYP1A1;BECN1 GO:0099133| ABCC10;ABCC1 GO:0006855| drug transmembrane transport ABCB1;SLC22A1;SLC22A3;ABCG2;ABCC1;SLC22A2 GO:0042908| xenobiotic transport ABCB1;NR1I2;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0016032| viral reproduction BECN1;FDPS GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2C9;CYP3A4;HSD17B2 41283:[DB00399 DB09291] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 41284:[DB00399 DB01351] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0006810| transport GABRA1;ABCC1;GABRA4;GABRA6;GRIK2;GABRA5;GABRA3 GO:0008202| steroid metabolic process FDPS;CYP2A6 GO:0055085| transmembrane transport ABCC1;GRIK2 41285:[DB00399 DB01380] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41286:[DB00399 DB00435] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2B6 GO:0042493| response to drug CYP1A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS 41287:[DB00399 DB13872] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0006810| transport GABRG2;GABRA1;ABCC1;GABRA5;GABRA3 41288:[DB00399 DB14503] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction FDPS;SLC20A2 GO:0006810| transport SLC20A2;SLC20A1;ABCC1 GO:0055085| transmembrane transport SLC20A2;SLC34A2;SLC20A1;ABCC1;SLC34A3 GO:0042493| response to drug SLC34A1;ABCC1 41289:[DB00399 DB06190] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06190|Solabegron ADRB3 common genes common pathways 41290:[DB00399 DB06787] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 41291:[DB00399 DB06652] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP3A4;CYP3A5 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 GO:0016032| viral reproduction CCR5;FDPS 41292:[DB00399 DB06412] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0006810| transport AR;ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;SRD5A1;CYP2D6;FDPS;CYP3A4 GO:0042493| response to drug ABCC1;SRD5A1 GO:0006694| steroid biosynthetic process SRD5A1;FDPS GO:0006629| lipid metabolic process SRD5A1;CYP2D6;FDPS;CYP3A4 41293:[DB00399 DB01228] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01228|Encainide SCN5A;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0055085| transmembrane transport ABCC1;SCN5A GO:0006629| lipid metabolic process FDPS;CYP2D6 41294:[DB00399 DB00604] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;CYP2D6 GO:0016032| viral reproduction HTR2A;FDPS GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP3A5;CYP3A7;CYP2A6;CYP3A4;CYP2D6;CYP2B6;CYP2C9;FDPS GO:0055085| transmembrane transport ABCC1;KCNH2 GO:0042493| response to drug ABCC1;HTR2A 41295:[DB00399 DB08901] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP2C8;FDPS;CYP2D6;CYP3A4 GO:0060326| cell chemotaxis PDGFRA;ABCC1;KIT GO:0042493| response to drug ABCB1;LYN;ABCC1;ABCG2;LCK;SRC;RET GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0016032| viral reproduction LYN;FDPS;PDGFRA;SRC;LCK;KDR GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 41296:[DB00399 DB11581] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;BCL2;ABCG2;ABCC1;SLCO1B1 GO:0042493| response to drug ABCB1;BCL2;ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41297:[DB00399 DB01138] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes ABCC1 common pathways GO:0042908| xenobiotic transport ABCC1;ABCC3;NR1I2 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCC3;ABCC2;ABCC1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 GO:0006810| transport ABCC1;ABCB11;ABCC6;ABCC2;ABCC5;ABCC3 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;NR1I2;FDPS;CYP3A4;CYP2C8 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport ABCB11;ABCC6;SLC22A12;ABCC1;ABCC4;ABCC3;ABCC2;ABCC5 GO:0099133| ABCC6;ABCC1;ABCC3;ABCC4;ABCC5;ABCC2 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC4;ABCC2;ABCC6;SLC22A12;ABCC1 GO:0060326| cell chemotaxis ABCC1 41298:[DB00399 DB06713] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process STS;FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS;STS GO:0006810| transport AR;ABCC1 41299:[DB00399 DB00637] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCB1;KCNH2;KCNH1;ABCC1;ABCB11 GO:0006810| transport ABCB1;ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4;CYP3A5;CYP3A7 GO:0042493| response to drug ABCC1;ABCB1 41300:[DB00399 DB01252] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0055085| transmembrane transport ABCC8;ABCC1 GO:0008202| steroid metabolic process UGT2B7;FDPS GO:0042493| response to drug ABCC1;ABCC8;PPARG GO:0099133| ABCC8;ABCC1 GO:0006629| lipid metabolic process FDPS;PPARG;UGT2B7 41301:[DB00399 DB06262] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0042493| response to drug ADRA1A;SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC16A10;ABCC1;SLC6A2 GO:0006810| transport SLC6A2;ABCC1 41302:[DB00399 DB01254] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 GO:0016032| viral reproduction FDPS;HSPA8;LYN;EPHA2;FYN;LCK;SRC GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 GO:0060326| cell chemotaxis EPHA2;PDGFRB;ABCC1;KIT GO:0042493| response to drug CYP1A1;SRC;PPAT;ABCC1;LCK;ABCG2;LYN;FYN;CYP1A2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP3A4;CYP1B1;CYP3A5;CYP1A1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB1 41303:[DB00399 DB01059] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A5 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP1A1;CYP3A5;CYP1A2;FDPS;CYP3A4 GO:0055085| transmembrane transport SLC22A5;SLC22A6;ABCC1 GO:0042493| response to drug CYP1A2;ABCC1;CYP1A1 41304:[DB00399 DB05303] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05303|OMS-103HP TNF;IL1R1 common genes common pathways 41305:[DB00399 DB00002] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FCGR2B;FDPS 41306:[DB00399 DB02701] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042493| response to drug CYP2E1;LDHA;ABCC1 GO:0008202| steroid metabolic process CYP2E1;CYP2D6;FDPS;CYP3A4 41307:[DB00399 DB00338] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0008203| cholesterol metabolic process CYP11A1;FDPS GO:0099133| ABCC1;ABCC3 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1;ABCG2;CYP1A1 GO:0006694| steroid biosynthetic process CYP11A1;FDPS GO:0006810| transport ATP4A;ABCC3;ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP1A1;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP1A2;CYP11A1;FDPS;CYP1B1;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCC3;ABCG2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;CYP11A1;FDPS;CYP2C9;CYP2D6 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1;ABCC3 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1;ABCC3 41308:[DB00399 DB09449] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction FDPS;SLC20A2 GO:0006810| transport SLC20A1;ABCC1;SLC20A2 GO:0055085| transmembrane transport SLC20A2;SLC34A2;SLC20A1;ABCC1;SLC34A3 GO:0042493| response to drug ABCC1;SLC34A1 41309:[DB00399 DB00083] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 41310:[DB00399 DB13269] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways GO:0055085| transmembrane transport SCN5A;SCN10A;ABCC1;SCN4A;SCN9A;SCN1A;SCN3A;SCN11A;SCN8A;SCN7A;SCN2A GO:0042493| response to drug ABCC1;SCN11A 41311:[DB00399 DB06772] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLCO1B3;ABCC1;ABCG2;SLCO1B1 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCG2;ABCC1 41312:[DB00399 DB13950] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13950|WIN 55212-2 CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41313:[DB00399 DB01126] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways GO:0042493| response to drug SRD5A2;ABCC1;SRD5A1 GO:0006694| steroid biosynthetic process FDPS;SRD5A2;SRD5A1 GO:0008202| steroid metabolic process SRD5A1;SRD5A2;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;SRD5A2;SRD5A1 41314:[DB00399 DB06370] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2D6;FDPS;CYP2E1 GO:0042493| response to drug ABCC1;CYP2E1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP2C9;CYP3A4 41315:[DB00399 DB13866] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13866|Etynodiol CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41316:[DB00399 DB09389] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0006810| transport AR;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4;SRD5A1 GO:0006694| steroid biosynthetic process CYP19A1;FDPS;SRD5A1 GO:0042493| response to drug SRD5A1;ABCC1 GO:0006629| lipid metabolic process SRD5A1;CYP3A4;FDPS 41317:[DB00399 DB12191] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12191|Obatoclax BCL2 common genes common pathways GO:0055085| transmembrane transport BCL2;ABCC1 GO:0042493| response to drug BCL2;ABCC1 41318:[DB00399 DB08807] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0042493| response to drug ABCC1;HTR1B GO:0006629| lipid metabolic process CYP2D6;FDPS 41319:[DB00399 DB11130] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0042493| response to drug B2M;ABCC1 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 41320:[DB00399 DB06734] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06734|Bafilomycin B1 ATP6V1A common genes common pathways GO:0006810| transport ABCC1;ATP6V1A 41321:[DB00399 DB00589] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0016032| viral reproduction FDPS;HTR2A GO:0042493| response to drug HTR2C;DRD3;HTR1B;DRD2;HTR2A;DRD1;ABCC1;HTR2B GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 41322:[DB00399 DB09502] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0055085| transmembrane transport SLC2A8;SLC2A12;SLC2A11;ABCC1;SLC2A2;SLC2A5;SLC2A3;SLC2A7;SLC2A1;SLC2A9;SLC2A6;SLC2A4;SLC2A10 GO:0042908| xenobiotic transport SLC2A1;ABCC1 41323:[DB00399 DB05505] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05505|NM-702 TBXAS1 common genes common pathways GO:0006629| lipid metabolic process TBXAS1;FDPS 41324:[DB00399 DB01200] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug HTR1B;ABCB1;DRD3;HTR2C;HTR2B;ABCC1;DRD2;ADRA1A;DRD1;HTR2A GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction HTR2A;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41325:[DB00399 DB01240] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0006629| lipid metabolic process PTGIS;FDPS 41326:[DB00399 DB05039] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process UGT1A1;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;UGT1A1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41327:[DB00399 DB04825] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport CALM1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 41328:[DB00399 DB05476] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05476|WX-UK1 PLAUR common genes common pathways 41329:[DB00399 DB09029] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09029|Secukinumab IL17A common genes common pathways 41330:[DB00399 DB00836] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;CALM1;ABCB1;CACNA1A GO:0008202| steroid metabolic process CYP2C8;CYP2B6;CYP2D6;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41331:[DB00399 DB00210] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0006629| lipid metabolic process FDPS;PTGS2 GO:0016032| viral reproduction FDPS;RXRA GO:0008203| cholesterol metabolic process FDPS;RXRA GO:0042493| response to drug PTGS2;ABCC1 41332:[DB00399 DB12332] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC47A1;SLC47A2;ABCB1;SLC22A1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 GO:0055085| transmembrane transport SLC22A6;SLCO1B1;SLC22A8;ABCG2;ABCC1;ABCC4;SLC47A1;SLCO1B3;ABCB1;SLC22A1;SLC47A2 GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;UGT1A1;CYP2C19;CYP2C8;CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0042493| response to drug ABCC4;CYP1A2;ABCB1;ABCG2;UGT1A1;ABCC1 GO:0099133| ABCC4;ABCC1 41333:[DB00399 DB05431] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05431|MLN-977 ALOX5 common genes common pathways GO:0006691| leukotriene metabolic process ABCC1;ALOX5 41334:[DB00399 DB02998] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0006810| transport AR;ABCC1 41335:[DB00399 DB14635] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP1A2;FDPS;PPARG;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCC5;ABCC1 GO:0006810| transport ABCB1;ABCC5;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;CYP2B6;FDPS;CYP1A2 GO:0042493| response to drug ABCC1;CYP1A2;PPARG;ABCB1 GO:0099133| ABCC1;ABCC5 41336:[DB00399 DB00877] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;SLC47A1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;SLC47A1;ABCC1;SLCO1B1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5;CYP3A7 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 41337:[DB00399 DB11712] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006695| cholesterol biosynthetic process CFTR;FDPS;GGPS1 GO:0099133| CFTR;ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;CFTR 41338:[DB00399 DB12334] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12334|Milataxel TUBB1;TUBB common genes common pathways 41339:[DB00399 DB07462] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways GO:0042493| response to drug ABCC1;COMT 41340:[DB00399 DB05668] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05668|Palifosfamide DNMT1 common genes common pathways 41341:[DB00399 DB03403] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways 41342:[DB00399 DB00685] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0042493| response to drug ABCC1;CYP1A2 GO:0008202| steroid metabolic process FDPS;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;FDPS 41343:[DB00399 DB06237] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41344:[DB00399 DB04074] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0055085| transmembrane transport SLC16A1;SLC16A7;ABCC1;SLC16A3 GO:0006629| lipid metabolic process SLC16A1;FDPS 41345:[DB00399 DB01102] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways 41346:[DB00399 DB11703] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP3A5;CYP3A7 41347:[DB00399 DB00655] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP1A2;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC22A8;SLCO1B1;SLCO2B1;SLCO1A2;ABCC1;ABCG2 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2C9;CYP2B6;CYP3A4;CYP1B1;CYP2E1;CYP3A5;CYP1A1 GO:0006810| transport ABCB1;ABCC1;ABCG2;AR GO:0006691| leukotriene metabolic process ABCC1;CYP4A11 GO:0042493| response to drug ABCC1;ABCG2;CYP1A1;CYP2E1;ABCB1;CYP1A2 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 41348:[DB00399 DB00696] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A2;ABCC1 GO:0006810| transport SLC6A2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug HTR2C;ABCB1;HTR1B;HTR2A;DRD1;DRD2;ADRA1A;ABCC1;SLC6A2;HTR2B GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41349:[DB00399 DB05087] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0006810| transport GABRA6;GABRA4;ABCC1;GABRA3;GABRA5;GABRA1 41350:[DB00399 DB04840] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0055085| transmembrane transport ABCB1;ABCC1;SLC6A2 GO:0006810| transport SLC6A2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP1A1;CYP2D6;FDPS GO:0042493| response to drug ABCC1;SLC6A2;CYP1A1;ABCB1 41351:[DB00399 DB00886] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00886|Omapatrilat ACE;MME common genes common pathways 41352:[DB00399 DB05351] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP2C19;CYP3A4;FDPS GO:0006810| transport ABCC1;ATP4A 41353:[DB00399 DB14642] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCC2 GO:0006810| transport ABCC2;ABCC1 GO:0055085| transmembrane transport ABCC2;ABCC1 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC2;ABCC1 41354:[DB00399 DB01219] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport RYR1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS 41355:[DB00399 DB00845] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006810| transport ABCB11;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB11;ABCC1;ABCB1 41356:[DB00399 DB09166] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0006810| transport GABRA1;GABRG2;GABRA3;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;FDPS 41357:[DB00399 DB04889] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0006810| transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCC1 GO:0042493| response to drug SLC6A4;ABCC1;SLC6A2;MAOB;DRD2 GO:0006629| lipid metabolic process CYP2D6;FDPS 41358:[DB00399 DB00782] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00782|Propantheline CHRM1 common genes common pathways 41359:[DB00399 DB14508] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006810| transport GRIA3;ABCC1 41360:[DB00399 DB00502] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00502|Haloperidol DRD2;DRD1;GRIN2B;HTR2A;DRD3;MCHR1;SLC18A2;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP3A4;CBR1;UGT1A9;CYP1A1;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCC1;SLC18A2 GO:0006810| transport ABCB1;GRIN2B;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2;CYP2C19;CYP3A5;CYP1A1;CYP3A7 GO:0042493| response to drug ABCB1;DRD3;CYP1A2;ABCC1;DRD2;CYP1A1;DRD1;HTR2A 41361:[DB00399 DB01008] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006691| leukotriene metabolic process MGST2;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4;MGST2 41362:[DB00399 DB06211] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways GO:0006691| leukotriene metabolic process DPEP1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A8 41363:[DB00399 DB00517] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways 41364:[DB00399 DB08838] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport SLC7A7;CHRNA1;ASIC3;ABCC1;CACNA1B GO:0055085| transmembrane transport SLC22A1;SLC22A3;CACNA1B;ABCC1;SLC22A2 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A1;SLC22A3 41365:[DB00399 DB00131] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0008202| steroid metabolic process PRKAA1;FDPS GO:0006695| cholesterol biosynthetic process PRKAA1;GGPS1;FDPS GO:0008203| cholesterol metabolic process PRKAA1;FDPS GO:0042493| response to drug ADCY1;ACSL1;CREB1;ABCC1 GO:0006694| steroid biosynthetic process PRKAA1;FDPS GO:0006629| lipid metabolic process ACSL1;FDPS;PRKAB1;PRKAA1;PRKAB2 GO:0016126| sterol biosynthetic process FDPS;PRKAA1 GO:0016032| viral reproduction FDPS;CREB1 41366:[DB00399 DB06288] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0042493| response to drug DRD3;HTR2A;DRD2;ABCC1 41367:[DB00399 DB00569] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00569|Fondaparinux SERPINC1;F10 common genes common pathways 41368:[DB00399 DB11358] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways GO:0006629| lipid metabolic process ELOVL5;FADS2;FADS1;FDPS 41369:[DB00399 DB09282] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways 41370:[DB00399 DB00237] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0042493| response to drug ABCC1;GABRG3 GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRA5;GABRA3;GABRB2;GABRB1;GRIK2;GABRA6;GABRA4;ABCC1;GABRD GO:0055085| transmembrane transport GRIK2;ABCC1 41371:[DB00399 DB11094] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41372:[DB00399 DB01080] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9 GO:0008202| steroid metabolic process FDPS;CYP2C9 GO:0055085| transmembrane transport ABCC1;SLC36A1 GO:0042493| response to drug ABCC1;ABAT 41373:[DB00399 DB09053] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4;CYP3A5 41374:[DB00399 DB00276] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;KCNH2;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 41375:[DB00399 DB00458] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00458|Imipramine SLC6A2;HTR2A;SLC6A4;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCND2;KCND3;HTR2C;ADRA1B;HTR7;DRD1;DRD5;DRD2;KCNH2;SLC6A3;HTR1A;HTR6;KCNH1;ORM2;CYP2C19;CYP2D6;CYP1A2;CYP3A4;CYP3A7;CYP2B6;CYP2C18;CYP2E1;ORM1;ALB;ABCB1;SLC22A2;SLC22A3;SLC22A4 common genes common pathways GO:0006810| transport ABCB1;SLC6A2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2B6;CYP2D6;CYP2C19;CYP2E1;CYP3A7 GO:0055085| transmembrane transport ABCB1;KCNH2;SLC22A4;KCND3;SLC6A4;SLC22A3;KCNH1;SLC6A2;ABCC1;SLC6A3;SLC22A2;KCND2 GO:0042493| response to drug ABCB1;SLC6A4;HTR2C;CYP1A2;SLC6A2;ABCC1;DRD2;ADRA1A;SLC6A3;DRD1;HTR2A;CYP2E1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC22A3;ABCC1;SLC22A2 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2D6;CYP3A4 GO:0016032| viral reproduction FDPS;HTR2A 41376:[DB00399 DB00346] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport KCNH2;ABCC1 GO:0042493| response to drug ADRA1A;ABCC1 41377:[DB00399 DB09265] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09265|Lixisenatide GLP1R common genes common pathways 41378:[DB00399 DB11586] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9 GO:0055085| transmembrane transport SLCO2B1;SLCO1B1;ABCC1;SLCO1B3;ABCB1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2B6;CYP2C9;CYP2D6;FDPS;CYP2C19;CYP3A5;CYP3A7 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 41379:[DB00399 DB00675] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0008202| steroid metabolic process CYP1B1;CYP3A4;CYP2A6;CYP2C9;CYP2B6;NR1I2;CYP2D6;FDPS;SULT1A1;CYP2C8;CYP2C19;EBP;CYP1A1;CYP3A5;CYP3A7;CYP2E1 GO:0006810| transport ABCC1;ABCG2;ABCB11;AR;ABCB1;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCC2;KCNH2;ABCC1;ABCG2;ABCB11 GO:0008203| cholesterol metabolic process FDPS;EBP GO:0006695| cholesterol biosynthetic process CES1;EBP;FDPS;GGPS1 GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug ABCB1;ABCC2;CYP2E1;CYP1A1;ABCG2;ABCC1 GO:0006694| steroid biosynthetic process EBP;FDPS;CYP19A1 GO:0060326| cell chemotaxis PRKCD;ABCC1;PRKCQ GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1;NR1I2 GO:0006855| drug transmembrane transport ABCC2;ABCB1;EBP;ABCG2;ABCC1 GO:0016126| sterol biosynthetic process FDPS;EBP GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;FDPS;SULT1A1;EBP 41380:[DB00399 DB14065] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41381:[DB00399 DB01019] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways 41382:[DB00399 DB08613] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0042493| response to drug ABCC1;HDAC4 41383:[DB00399 DB01496] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0006810| transport GABRA1;GABRA3;GABRA5;GABRA4;GABRA6;GRIK2;ABCC1 GO:0055085| transmembrane transport GRIK2;ABCC1 41384:[DB00399 DB04948] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0055085| transmembrane transport SLC47A1;ABCC1;ABCB5 GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP1A2;CYP2D6 GO:0042493| response to drug HTR2C;CYP1A2;ABCC1;ADRA1A GO:0006855| drug transmembrane transport ABCB5;ABCC1;SLC47A1 GO:0042908| xenobiotic transport ABCC1;ABCB5 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6 41385:[DB00399 DB11637] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41386:[DB00399 DB13994] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways GO:0006810| transport GABRA3;ABCC1 41387:[DB00399 DB00414] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS GO:0008202| steroid metabolic process CYP2C9;FDPS 41388:[DB00399 DB00565] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00565|Cisatracurium CHRNA2 common genes common pathways 41389:[DB00399 DB08502] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08502|Capravirine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41390:[DB00399 DB00494] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0042493| response to drug ABCC1;COMT GO:0008202| steroid metabolic process CYP2D6;FDPS 41391:[DB00399 DB01548] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways 41392:[DB00399 DB06148] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0055085| transmembrane transport SLC6A4;SLC6A2;ABCC1;SLC6A3 GO:0006810| transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2D6;CYP2B6;CYP3A4 GO:0042493| response to drug HTR2A;DRD1;SLC6A3;ADRA1A;DRD2;SLC6A2;ABCC1;HTR2B;CYP1A2;HTR2C;SLC6A4;DRD3 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP3A4 41393:[DB00399 DB12093] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0042493| response to drug ABCC1;DRD2;DRD1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41394:[DB00399 DB00315] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0042493| response to drug CYP1A2;HTR1B;ABCC1 41395:[DB00399 DB11064] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0006810| transport AR;ABCC1 41396:[DB00399 DB07720] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways 41397:[DB00399 DB05201] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05201|V24343 CNR1 common genes common pathways 41398:[DB00399 DB03566] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A1;SLC22A4 41399:[DB00399 DB01074] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways GO:0042493| response to drug CPT1A;ABCC1 GO:0055085| transmembrane transport ABCC1;KCNH2 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2B6;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS;CPT1A;CYP2D6;CPT2 41400:[DB00399 DB05091] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05091|M0002 AVPR2 common genes common pathways 41401:[DB00399 DB06595] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP3A4;CYP3A7;CYP2E1;CYP3A5;CYP2C19;CYP2C8 GO:0042493| response to drug CYP1A2;CYP2E1;ABCC1 GO:0060326| cell chemotaxis ABCC1;KIT;PDGFRA;PDGFRB GO:0016032| viral reproduction PDGFRA;KDR;FDPS GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6 41402:[DB00399 DB00790] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug ABCC1;BCHE GO:0006810| transport SLC15A1;SLC15A2;ABCC1 GO:0055085| transmembrane transport SLC15A1;SLC15A2;ABCC1 41403:[DB00399 DB01296] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2C19;CYP2E1 GO:0042493| response to drug ABCC1;CYP2E1 41404:[DB00399 DB12866] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12866|Pradigastat SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC22A8 41405:[DB00399 DB00849] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCC1 GO:0055085| transmembrane transport ABCC1;GRIK2 GO:0006810| transport GABRA1;GABRA3;GABRA5;GRIK2;GABRA6;GABRA4;ABCC1 GO:0008202| steroid metabolic process CYP2C19;NR1I2;CYP2B6;FDPS 41406:[DB00399 DB01412] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;ADORA2A;ABCC1;CYP2E1 41407:[DB00399 DB04674] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0006810| transport ABCC1;TTR 41408:[DB00399 DB04827] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways GO:0006629| lipid metabolic process FDPS;PLA2G4A 41409:[DB00399 DB00521] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process FDPS;CYP2D6 41410:[DB00399 DB00549] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2C9;CYP3A4;CYP2E1;CYP2C19;CYP2C8 GO:0006810| transport ABCC1;ABCG2 GO:0055085| transmembrane transport ABCC1;ABCG2 GO:0042493| response to drug CYP2E1;ABCC1;ABCG2;CYP1A2 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP3A4;PTGS1 41411:[DB00399 DB00531] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;NR1I2;CYP2B6;CYP2C9;FDPS;CYP2A6;CYP3A4 GO:0042908| xenobiotic transport ABCC1;NR1I2 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 41412:[DB00399 DB06700] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A4 GO:0042493| response to drug SLC6A4;ABCC1;SLC6A2 41413:[DB00399 DB00852] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0055085| transmembrane transport SLC6A3;SLC6A2;ABCC1;SLC6A4 GO:0006810| transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0042493| response to drug FOS;SLC6A3;ADRA1A;JUN;SLC6A2;ABCC1;SLC6A4 GO:0016032| viral reproduction FDPS;ATF7 GO:0006629| lipid metabolic process FDPS;CYP2D6 41414:[DB00399 DB05022] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05022|Amonafide TOP2A;TOP2B common genes common pathways 41415:[DB00399 DB00534] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways GO:0006810| transport SLC12A1;ABCC1 GO:0055085| transmembrane transport SLC12A1;ABCC1 41416:[DB00399 DB01588] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRA5;GABRA3;GABRB2;ABCC1;GABRR2;GABRD;GABRB1;GABRA6;GABRR1;GABRA4 GO:0042493| response to drug GABRG3;ABCC1 41417:[DB00399 DB00963] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1;FDPS 41418:[DB00399 DB00396] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes ABCC1 common pathways GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;NR1I2;ABCG2;ABCC1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A3;ABCC1;ABCG2;SLC22A2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS GO:0034775| glutathione transmembrane transport ABCC1 GO:0016032| viral reproduction FDPS;SLC10A1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP3A7;CYP1A1;CYP3A5;CYP17A1;CYP2A6;CYP3A4;CYP1B1;FDPS;NR1I2;CYP2C9;CYP2D6 GO:0006810| transport ABCB11;AR;ABCC1;ABCG2;SLC10A1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A1;SLC22A3;SLC10A1;ABCG2;ABCC1;SLCO1B1;ABCB11;SLC22A2 GO:0006694| steroid biosynthetic process FDPS;CYP17A1 GO:0060326| cell chemotaxis ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCB1;CYP1A1;ABCC1;ABCG2 GO:0099133| ABCC1 41419:[DB00399 DB06138] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06138|IRL-1620 EDNRB common genes common pathways 41420:[DB00399 DB00289] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0042493| response to drug SLC6A4;GRIN2A;SLC6A3;SLC6A2;ABCC1 GO:0006810| transport GRIN2C;SLC6A2;ABCC1;GRIN2A;GRIN2B GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP2C19 GO:0055085| transmembrane transport SLC6A4;ABCC1;SLC6A2;SLC6A3 41421:[DB00399 DB00946] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00946|Phenprocoumon VKORC1;CYP2C8;CYP2C9;CYP3A4;ALB;ORM1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP3A4;CYP2C8 41422:[DB00399 DB06751] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0055085| transmembrane transport CACNA1C;ABCC1 41423:[DB00399 DB04926] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04926|Neramexane GRIN3A common genes common pathways 41424:[DB00399 DB01650] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;ABCC1 41425:[DB00399 DB05521] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A5;FDPS;CYP3A4 GO:0055085| transmembrane transport SLCO1B1;SLCO2B1;ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 41426:[DB00399 DB01257] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01257|Eculizumab C5 common genes common pathways GO:0060326| cell chemotaxis ABCC1;C5 41427:[DB00399 DB00150] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways GO:0006810| transport ABCC1;SLC16A2 GO:0055085| transmembrane transport SLC16A10;SLC16A2;ABCC1 41428:[DB00399 DB12035] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12035|Sarecycline ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41429:[DB00399 DB01288] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways 41430:[DB00399 DB08827] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process MTTP;CYP3A4;FDPS 41431:[DB00399 DB06155] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41432:[DB00399 DB06274] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways 41433:[DB00399 DB11431] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042493| response to drug ABCB1;ABCG2;ABCC1 41434:[DB00399 DB06292] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process UGT2B7;CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCC1;SLC5A2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2A6;UGT2B7;CYP1A1 GO:0006810| transport ABCC1;SLC5A2;ABCB1 GO:0042493| response to drug ABCC1;CYP1A1;ABCB1;CYP1A2 41435:[DB00399 DB00715] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0055085| transmembrane transport SLC6A4;ABCB1;ABCC1;SLC6A2 GO:0006810| transport SLC6A2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP1A2;FDPS;CYP2C9;CYP2B6;CYP2D6;CYP3A4 GO:0042493| response to drug HTR2A;ABCC1;SLC6A2;CYP1A2;SLC6A4;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 41436:[DB00399 DB05688] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways GO:0042493| response to drug SLC6A2;ABCC1;SLC6A4 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A4 41437:[DB00399 DB01483] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;FDPS GO:0006810| transport GABRA3;GABRA5;ABCC1;GRIK2;GABRA6;GABRA4;GABRA1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41438:[DB00399 DB06579] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0006810| transport ABCC1;GABRA6;GABRA4;GABRA3;GABRA5;GABRG2;GABRA1 GO:0042493| response to drug ABCC1;GABRG3 41439:[DB00399 DB00834] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes ABCC1 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport NR1I2;ABCB1;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0060326| cell chemotaxis ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0099133| ABCC1 GO:0055085| transmembrane transport ABCB1;ABCB11;ABCC1 GO:0006810| transport ABCC1;ABCB11;ABCB1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP3A7;CYP3A5;CYP3A4;FDPS;CYP2D6;NR1I2;CYP2C9 41440:[DB00399 DB14069] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14069|ONT-093 ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 41441:[DB00399 DB01551] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 41442:[DB00399 DB00978] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCC2 GO:0042493| response to drug ABCC1;CYP1A2;ABCC2 GO:0099133| ABCC2;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A5;ABCC2 GO:0006810| transport ABCC2;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 41443:[DB00399 DB05034] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05034|Ularitide NPR1 common genes common pathways 41444:[DB00399 DB06603] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0016032| viral reproduction HDAC1;FDPS GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug HDAC2;ABCC1;HDAC1;HDAC5;ABCB1;HDAC4 41445:[DB00399 DB09030] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41446:[DB00399 DB06342] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41447:[DB00399 DB04299] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways GO:0016032| viral reproduction FDPS;TPR 41448:[DB00399 DB00537] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP3A4;CYP3A5;CYP3A7 GO:0055085| transmembrane transport SLC47A1;ABCB1;SLC47A2;KCNH2;ABCC1 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;SLC47A2;SLC47A1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 41449:[DB00399 DB00713] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport SLC15A1;ABCC1;SLC15A2 GO:0006810| transport SLC15A1;ABCC1;SLC15A2 41450:[DB00399 DB14055] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14055|(S)-Warfarin CYP3A4;CYP2C8;CYP2C9;CYP2C18;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2C9;FDPS;CYP3A4 41451:[DB00399 DB00305] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00305|Mitomycin POR common genes common pathways GO:0042493| response to drug POR;ABCC1 41452:[DB00399 DB01047] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41453:[DB00399 DB00501] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00501|Cimetidine HRH2;CYP1A2;CYP2C19;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP11B1;CYP2C8;CYP2C9;CYP2E1;FMO3;FMO1;ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A6;SLC22A8;SLC47A1;SLC22A4;SLC22A11;SLC22A7;ABCB11;SLC47A2 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2E1;CYP3A7;CYP11B1;CYP3A5;CYP2C19;CYP2C8 GO:0006810| transport ABCB11;ABCC1;ABCB1 GO:0055085| transmembrane transport SLC22A6;SLC22A2;ABCB11;SLC22A5;SLC22A8;SLC22A7;ABCC1;SLC22A11;SLC22A3;SLC47A1;SLC22A1;ABCB1;SLC22A4;SLC47A2 GO:0006694| steroid biosynthetic process CYP11B1;FDPS GO:0042493| response to drug CYP2E1;ABCC1;CYP1A2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A5;ABCB1;SLC22A1;SLC47A2;SLC47A1;SLC22A3 GO:0006629| lipid metabolic process CYP11B1;CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 41454:[DB00399 DB00619] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0016032| viral reproduction PDGFRA;FDPS GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;FDPS;PTGS1 GO:0006855| drug transmembrane transport SLC22A1;ABCB1;SLC22A2;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0042493| response to drug RET;ABCA3;ABCG2;ABCC1;CYP1A2;NTRK1;ABCB1 GO:0060326| cell chemotaxis PDGFRB;PDGFRA;ABCC1;KIT GO:0055085| transmembrane transport SLC22A1;ABCB1;ABCC1;ABCG2;ABCA3;SLC22A2;ABCB11 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP2C19;CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0006810| transport ABCB1;ABCG2;ABCC1;ABCA3;ABCB11 41455:[DB00399 DB01263] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;ABCB1 41456:[DB00399 DB08882] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 41457:[DB00399 DB08900] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08900|Teduglutide GLP2R common genes common pathways 41458:[DB00399 DB00182] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0006855| drug transmembrane transport SLC22A5;ABCC1;SLC22A3 GO:0042493| response to drug ABCC1;SLC6A2;DRD2;ADRA1A;SLC6A3;MAOB;SLC6A4 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC18A2;SLC6A3;SLC22A5;SLC6A4;SLC22A3 GO:0006810| transport SLC6A2;ABCC1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP2A6 41459:[DB00399 DB00921] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;FDPS GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1;UGT1A1;ABCG2 GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP2C19;CYP2C8;UGT1A1;FDPS;CYP2D6;CYP2C9;CYP3A4;CYP2A6 41460:[DB00399 DB01590] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport SLCO1B3;SLCO1B1;SLCO1A2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS 41461:[DB00399 DB00661] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes ABCC1 common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;FDPS GO:0034775| glutathione transmembrane transport ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC3;ABCC1;ABCG2 GO:0006855| drug transmembrane transport SLC22A5;ABCG2;ABCC1;ABCC3;ABCC2;ABCB1;SLC22A1 GO:0060326| cell chemotaxis ABCC1 GO:0042493| response to drug CYP1A2;ABCC4;SLC6A4;ABCB1;ABCC2;ADRA1A;KCNJ11;ABCC1;ABCG2 GO:0006691| leukotriene metabolic process ABCC1 GO:0099133| ABCC4;ABCC3;ABCC2;ABCC10;ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP3A7;CYP3A5 GO:0006810| transport ABCB11;CACNB3;ABCC1;ABCG2;CACNB1;CACNA1B;CACNB4;ABCC3;CACNA1I;ABCC2;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCC1;CACNA1S;SCN5A;SLCO1A2;CACNA1B;KCNJ11;CACNA1C;CACNA1D;SLC22A5;ABCB11;ABCC10;SLCO1B1;CACNA1F;ABCB1;ABCC2;SLC22A1;SLC6A4;SLC22A4;KCNH2;CACNA1I;CACNA1A;ABCC3;CACNA1G;ABCC4 41462:[DB00399 DB01367] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01367|Rasagiline MAOB;BCL2;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;BCL2;ABCC1;MAOB GO:0008202| steroid metabolic process FDPS;CYP1A2 GO:0055085| transmembrane transport ABCC1;BCL2 GO:0006629| lipid metabolic process FDPS;CYP1A2 41463:[DB00399 DB01307] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01307|Insulin Detemir INSR;ALB common genes common pathways 41464:[DB00399 DB01571] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways 41465:[DB00399 DB00353] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;HTR2B;DRD1 GO:0008202| steroid metabolic process FDPS;CYP3A4 41466:[DB00399 DB08820] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099133| ABCC1;CFTR GO:0042493| response to drug ABCB1;ABCC1 GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CFTR GO:0055085| transmembrane transport ABCB1;ABCC1;CFTR GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5 41467:[DB00399 DB00324] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41468:[DB00399 DB04938] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;CYP2D6 GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP3A4 41469:[DB00399 DB13878] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A7;UGT1A1;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCG2;ABCC1;SLCO1B1;ABCB1;SLCO1B3 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41470:[DB00399 DB13961] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PPARG;DGAT2;CYP3A4;PPARA;PPARD;FDPS;SREBF1;PTGS2 GO:0055085| transmembrane transport CACNA1S;ABCC1;CACNA1D;CACNA1C;CACNA1F GO:0045540| regulation of cholesterol biosynthetic process SREBF1;FDPS;GGPS1 GO:0006810| transport CACNB4;CACNB1;CACNB3;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4;SREBF1 GO:0042493| response to drug PPARG;ABCC1;SREBF1;PTGS2 GO:0008203| cholesterol metabolic process FDPS;PPARD;SREBF1 41471:[DB00399 DB00261] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;PDE3A GO:0042493| response to drug CYP1A2;PDE3A;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 41472:[DB00399 DB00444] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0055085| transmembrane transport ABCC6;ABCC1;ABCG2 GO:0006810| transport ABCC1;ABCG2;ABCC6 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;FDPS;CYP2C19;CYP3A5 GO:0099133| ABCC6;ABCC1 GO:0042493| response to drug ABCC6;ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4 41473:[DB00399 DB01098] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes ABCC1 common pathways GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2 GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4;HMGCR GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C9;HMGCR;CYP2C19;CYP3A5 GO:0006810| transport ABCC1;ABCG2;ABCB11;ABCC2 GO:0055085| transmembrane transport ABCC4;SLCO1B3;ABCC2;SLCO2B1;SLCO1B1;SLC22A8;ABCB11;ABCG2;ABCC1;SLCO1A2 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;FDPS;GGPS1 GO:0008299| isoprenoid biosynthetic process HMGCR;FDPS;GGPS1 GO:0008203| cholesterol metabolic process HMGCR;FDPS GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0042493| response to drug ABCG2;ABCC1;ABCC2;ABCC4 GO:0006691| leukotriene metabolic process ABCC1 GO:0099133| ABCC1;ABCC2;ABCC4 GO:0006694| steroid biosynthetic process HMGCR;FDPS GO:0060326| cell chemotaxis ABCC1 41474:[DB00399 DB01236] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:0042493| response to drug ABCC1;CYP2E1;GABRG3;MT-ND1 GO:0055085| transmembrane transport ABCC1;KCNA1 GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRA5;GABRA3;GABRB2;ABCC1;GABRD;GABRB1;GABRA4;GABRA6 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2B6;FDPS;CYP2E1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41475:[DB00399 DB13954] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;NR1I2;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2;ABCC1;ABCG2 GO:0006629| lipid metabolic process HSD17B2;CYP3A4;FDPS;CYP1A2;CYP2C9 GO:0016032| viral reproduction FDPS;BECN1 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP1B1;CYP3A4;CYP2C9;NR1I2;FDPS;CYP1A2;CYP2C8;CYP2C19;UGT1A1;CYP3A5;CYP1A1;CYP3A7 GO:0055085| transmembrane transport SLCO1C1;SLC22A1;ABCB1;SLCO1B3;SLC22A3;SLCO1A2;SLC22A11;ABCC1;ABCG2;SLCO1B1;ABCC10;SLC22A8;SLCO4A1;SLCO2B1;SLC22A2 GO:0006694| steroid biosynthetic process FDPS;HSD17B2 GO:0042493| response to drug CYP1A1;BECN1;ABCG2;UGT1A1;ABCC1;CYP1A2;ABCB1 GO:0099133| ABCC10;ABCC1 41476:[DB00399 DB01593] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0055085| transmembrane transport APOA1;ABCC1 GO:0008202| steroid metabolic process FDPS;APOL1;APOE;APOBR;APOA1 GO:0006810| transport ABCC1;TTR GO:0060326| cell chemotaxis ABCC1;C5 GO:0042493| response to drug SOD1;HDAC1;TP53;TP73;NME1;ABCC1;APOA1;HDAC4;APOA2;MGMT;MDM2 GO:0008203| cholesterol metabolic process FDPS;APOA2;APOA4;APP;APOL1;APOBR;APOE;PON1;APOA1 GO:0006695| cholesterol biosynthetic process APOA1;GGPS1;APOA4;FDPS GO:0016032| viral reproduction APOA2;FDPS;CFH;MDM2;TP73;HDAC1;TP53;IDE;SIVA1 GO:0006629| lipid metabolic process CLU;FDPS;PON1;C3;APOA1;APOL1;APOE;APOBR 41477:[DB00399 DB00075] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction CD247;FCGR2B;FDPS 41478:[DB00399 DB09063] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 41479:[DB00399 DB00607] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2 GO:0055085| transmembrane transport ABCC1;SLC22A6 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP3A4 GO:0042493| response to drug ABCC1;CYP1A2 41480:[DB00399 DB05932] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways 41481:[DB00399 DB06786] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41482:[DB00399 DB00514] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC6A2;SLC6A4 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A5;CYP3A7;CYP2E1;CYP3A4;CYP2D6;CYP2B6;CYP2C9;FDPS GO:0006810| transport ABCC1;SLC6A2 GO:0042493| response to drug SLC6A4;CYBB;ABCC1;SLC6A2;CYBA;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS 41483:[DB00399 DB01101] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;FDPS;GGPS1 GO:0042493| response to drug TYMS;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;FDPS 41484:[DB00399 DB13141] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A7;FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41485:[DB00399 DB13867] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;SLCO1B1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 41486:[DB00399 DB01275] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41487:[DB00399 DB12092] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12092|Naftopidil CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41488:[DB00399 DB07280] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways 41489:[DB00399 DB00342] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A7;CYP3A5;CYP3A4;FDPS;CYP2D6 GO:0006810| transport ABCB1;ABCB11;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB11;ABCB1;KCNH2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 41490:[DB00399 DB00398] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0006810| transport ABCC2;ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP2C19;CYP2C8;UGT1A1;CYP2D6;CYP2B6;CYP2C9;FDPS;CYP1A2;CYP3A4 GO:0055085| transmembrane transport ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1;ABCG2;ABCC1 GO:0060326| cell chemotaxis PDGFRB;ABCC1;KIT GO:0042493| response to drug RET;ABCG2;ABCC1;UGT1A1;ABCC4;CYP1A2;ABCB1;ABCC2 GO:0099133| ABCC2;ABCC4;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCG2;ABCC1;RALBP1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2 GO:0016032| viral reproduction FDPS;KDR 41491:[DB00399 DB14061] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14061|Hycanthone ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 41492:[DB00399 DB09034] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41493:[DB00399 DB01242] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01242|Clomipramine SLC6A4;HTR2A;HTR2B;HTR2C;SLC6A2;GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;ALB;ABCB1 common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug ABCB1;SLC6A4;HTR2C;CYP1A2;ABCC1;SLC6A2;HTR2B;HTR2A GO:0055085| transmembrane transport SLC6A2;ABCC1;ABCB1;SLC6A4 GO:0006810| transport SLC6A2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6;CYP2C19 41494:[DB00399 DB06458] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06458|Remacemide CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41495:[DB00399 DB00470] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A1;ABCG2;ABCC1;ABCB1 GO:0055085| transmembrane transport ABCG2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;FDPS;CYP2C9;CYP2C19;CYP1A1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0006629| lipid metabolic process PTGS1;CYP3A4;CYP2C9;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 41496:[DB00399 DB01336] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways 41497:[DB00399 DB06655] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways 41498:[DB00399 DB04539] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways GO:0006694| steroid biosynthetic process FDPS;CYP19A1 41499:[DB00399 DB00559] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 GO:0055085| transmembrane transport ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;FDPS GO:0006810| transport ABCC1;ABCB11 41500:[DB00399 DB00823] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41501:[DB00399 DB05372] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05372|CP-945598 CNR1 common genes common pathways 41502:[DB00399 DB01154] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0055085| transmembrane transport KCNJ11;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;FDPS;CYP2E1 GO:0006810| transport GABRA1;ABCC1 GO:0042493| response to drug CYP2E1;KCNJ11;ABCC1 41503:[DB00399 DB06779] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways 41504:[DB00399 DB05501] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0016032| viral reproduction CXCR4;FDPS;CCR5 41505:[DB00399 DB06702] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41506:[DB00399 DB01426] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01426|Ajmaline SCN5A;ORM1 common genes common pathways GO:0055085| transmembrane transport ABCC1;SCN5A 41507:[DB00399 DB00462] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways 41508:[DB00399 DB00351] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 41509:[DB00399 DB04858] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04858|Tirapazamine CYP2E1 common genes common pathways GO:0042493| response to drug ABCC1;CYP2E1 GO:0008202| steroid metabolic process FDPS;CYP2E1 41510:[DB00399 DB11672] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4;PPARG GO:0006810| transport ABCC1;ABCC5;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9;CYP2B6 GO:0055085| transmembrane transport ABCC1;ABCB1;ABCC5 GO:0099133| ABCC5;ABCC1 GO:0042493| response to drug CYP1A2;ABCB1;PPARG;ABCC1 41511:[DB00399 DB02032] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 41512:[DB00399 DB00668] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;SLC22A2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C9 GO:0042493| response to drug ADRA1A;MAOB;ABCC1;COMT GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A1 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 41513:[DB00399 DB00394] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5 41514:[DB00399 DB00286] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes ABCC1 common pathways GO:0042493| response to drug ABCG2;ABCC1;COMT;ABCC4;CYP1A2;ABCC2;ABCB1 GO:0006691| leukotriene metabolic process ABCC1 GO:0099133| ABCC4;ABCC3;ABCC11;ABCC2;ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC11;ABCC2;SLCO1C1;SLC51A;ABCC4;SLCO1B3;SLC10A1;ABCC3;SLC22A11;SLCO1A2;SLCO3A1;ABCG2;SLC51B;ABCC1;SLCO4A1;SLC22A8;SLCO1B1;SLCO2B1;SLC22A10;SLC22A6 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2 GO:0006810| transport ABCC2;ABCB1;SLC10A1;ABCC3;ABCG2;ABCC1 GO:0016032| viral reproduction SLC10A1;FDPS GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2;ABCB1;ABCC3 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC3;ABCG2;ABCC1 41515:[DB00399 DB00811] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways 41516:[DB00399 DB05395] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05395|Amibegron ADRB3 common genes common pathways 41517:[DB00399 DB01017] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC22A11;SLC22A6;SLC22A7;SLC22A8 GO:0006691| leukotriene metabolic process ALOX5;ABCC1 GO:0042493| response to drug CASP3;ABCC1 41518:[DB00399 DB01149] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLC6A4;KCNH2;SLC6A3;SLCO2B1;ABCB11;ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP3A5;CYP3A7 GO:0006810| transport ABCB11;SLC6A2;ABCC1;ABCB1 GO:0042493| response to drug ADRA1A;SLC6A3;HTR2A;ABCC1;SLC6A2;HTR2C;ABCB1;SLC6A4 41519:[DB00399 DB05478] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41520:[DB00399 DB11582] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0042493| response to drug GABRG3;ABCC1 GO:0006810| transport GABRG2;GABRB3;GABRA1;GABRB1;GABRA6;GABRA4;ABCC1;GABRD;GABRA3;GABRA5;GABRB2 41521:[DB00399 DB01190] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41522:[DB00399 DB00982] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00982|Isotretinoin RARA common genes common pathways 41523:[DB00399 DB00202] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0042493| response to drug BCHE;ABCC1 41524:[DB00399 DB13178] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13178|Inositol SLC5A3 common genes common pathways GO:0006810| transport SLC5A3;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC5A3 41525:[DB00399 DB01364] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0042493| response to drug BCHE;ADRA1A;ABCC1;SLC6A2 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC18A2;SLC6A2;ABCC1 41526:[DB00399 DB06697] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;FDPS GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2B6;CYP2D6;FDPS;CYP2C19;CYP3A5 41527:[DB00399 DB01095] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCC2 GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0006629| lipid metabolic process HMGCR;UGT2B7;CYP3A4;FDPS;CYP2C9;CYP2D6 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;GGPS1;FDPS GO:0055085| transmembrane transport ABCC1;SLCO2B1;SLCO1B1;ABCC2;SLC15A1;SLCO1B3 GO:0008299| isoprenoid biosynthetic process FDPS;GGPS1;HMGCR GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2B6;CYP2C9;CYP2D6;HMGCR;UGT1A1;CYP2C19;CYP2C8;UGT2B7;CYP1A1;CYP3A5 GO:0006810| transport SLC15A1;ABCC2;ABCC1 GO:0042493| response to drug CYP1A1;ABCC1;UGT1A1;ABCC2 GO:0099133| ABCC1;ABCC2 GO:0006694| steroid biosynthetic process HMGCR;FDPS GO:0008203| cholesterol metabolic process FDPS;HMGCR GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;HMGCR 41528:[DB00399 DB14063] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41529:[DB00399 DB04953] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways GO:0042493| response to drug UGT1A1;ABCC1 GO:0008202| steroid metabolic process FDPS;UGT1A1 GO:0055085| transmembrane transport KCNQ5;KCNQ3;KCNQ4;KCNQ2;ABCC1 41530:[DB00399 DB06707] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways 41531:[DB00399 DB09143] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09143|Sonidegib SMO;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41532:[DB00399 DB00293] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0042493| response to drug ABCC1;TYMS 41533:[DB00399 DB00320] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;HTR2B;ABCB1;HTR1B GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41534:[DB00399 DB00835] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP2E1;CYP3A4;FDPS;CYP2B6 GO:0042493| response to drug ABCC1;CYP2E1 41535:[DB00399 DB01213] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;CYP2A6;FDPS GO:0042493| response to drug CAT;ABCC1;CYP2E1 GO:0008203| cholesterol metabolic process CAT;FDPS 41536:[DB00399 DB00368] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0055085| transmembrane transport SLC22A5;SLC22A2;SLC18A2;SLC18A1;SLC6A2;ABCC1;SLC22A3;SLC22A1 GO:0006810| transport ABCC1;SLC6A2 GO:0042493| response to drug ADRA1A;ABCC1;SLC6A2 GO:0006855| drug transmembrane transport SLC22A1;SLC22A3;SLC18A1;ABCC1;SLC22A5;SLC22A2 41537:[DB00399 DB02751] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02751|Glycocyamine GAMT common genes common pathways 41538:[DB00399 DB00074] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0016032| viral reproduction FCGR2B;IL2RB;FDPS 41539:[DB00399 DB00755] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes common pathways GO:0008203| cholesterol metabolic process RXRA;FDPS GO:0006694| steroid biosynthetic process NR0B1;FDPS GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 GO:0042493| response to drug ABCC1;CYP1A1 GO:0008202| steroid metabolic process CYP2C8;CYP3A7;CYP3A5;CYP1A1;CYP3A4;CYP2A6;FDPS;CYP2C9;CYP2B6 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4;HPGDS GO:0016032| viral reproduction RXRA;FDPS 41540:[DB00399 DB03128] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;SLC22A5;ABCC1 GO:0006855| drug transmembrane transport SLC22A1;ABCC1;SLC22A5 41541:[DB00399 DB01306] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01306|Insulin Aspart INSR common genes common pathways 41542:[DB00399 DB14570] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41543:[DB00399 DB05773] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP3A5 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 41544:[DB00399 DB00148] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0055085| transmembrane transport SLC6A8;SLC22A5;ABCC1 GO:0006810| transport SLC6A8;ABCC1 GO:0006855| drug transmembrane transport SLC22A5;ABCC1 41545:[DB00399 DB01614] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0042493| response to drug ABCC1;DRD1;HTR2A;DRD2;ADRA1A 41546:[DB00399 DB13151] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways 41547:[DB00399 DB00475] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;GABRD;GABRB1;GABRA6;GABRA4;GABRA5;GABRA3;GABRB2;GABRG2;GABRB3;GABRA1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug GABRG3;ABCC1 41548:[DB00399 DB01431] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41549:[DB00399 DB01610] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways GO:0006810| transport SLC15A2;ABCC1;SLC15A1;SLC6A14 GO:0055085| transmembrane transport ABCC1;SLC15A2;SLC6A14;SLC15A1 41550:[DB00399 DB01382] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0099133| ABCC1;ABCC8 GO:0042493| response to drug ABCC1;ABCC8 GO:0055085| transmembrane transport ABCC8;ABCC1 41551:[DB00399 DB08836] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways GO:0006810| transport ABCC1;SLC15A1 GO:0055085| transmembrane transport ABCC1;SLCO1A2;SLC15A1 41552:[DB00399 DB00714] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0042493| response to drug HTR2B;ABCC1;DRD1;HTR2A;DRD2;HTR1B;DRD3;HTR2C 41553:[DB00399 DB09099] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41554:[DB00399 DB06699] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06699|Degarelix GNRHR common genes common pathways 41555:[DB00399 DB00176] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug CYP1A1;CYP2E1;ABCC1;CYP1A2;ABCB1;SLC6A4 GO:0008202| steroid metabolic process CYP3A5;CYP1A1;CYP3A7;CYP2E1;CYP2C8;CYP2C19;CYP2D6;CYP2C9;CYP2B6;FDPS;CYP1A2;CYP3A4 GO:0006810| transport ABCB11;ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB11;ABCC1;ABCB1;SLC6A4;KCNH2 41556:[DB00399 DB06822] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0060326| cell chemotaxis ABCC1;CXCL12 41557:[DB00399 DB00200] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways GO:0015889| cobalamin transport TCN1;TCN2;ABCC1;CUBN;AMN GO:0006629| lipid metabolic process CUBN;FDPS GO:0009235| cobalamin metabolic process TCN2;TCN1;MTRR;ABCC1;MTR;CUBN;AMN;MUT;MMAB;MMACHC;MMAA GO:0008202| steroid metabolic process FDPS;CUBN GO:0008203| cholesterol metabolic process CUBN;FDPS 41558:[DB00399 DB09564] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09564|Insulin Degludec INSR common genes common pathways 41559:[DB00399 DB11921] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11921|Deflazacort CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41560:[DB00399 DB01289] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;FDPS GO:0006629| lipid metabolic process CYP2C9;FDPS 41561:[DB00399 DB00762] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes ABCC1 common pathways GO:0006810| transport ABCC2;ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;UGT1A1;FDPS;CYP2B6;CYP3A4 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport SLC22A3;ABCB1;ABCC2;SLCO1B1;ABCC1;ABCG2 GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CES1 GO:0099133| ABCC1;ABCC2 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug BCHE;ABCC2;ABCB1;TOP1;ABCC1;UGT1A1;ABCG2 GO:0060326| cell chemotaxis ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;SLC22A3;ABCB1;ABCC2 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 GO:0016032| viral reproduction FDPS;TOP1 41562:[DB00399 DB00243] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0006810| transport ABCB11;ABCC1 GO:0055085| transmembrane transport SCN9A;ABCB11;SCN5A;ABCC1 41563:[DB00399 DB06191] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1;SLCO1B1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 41564:[DB00399 DB04334] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04334|6-hydroxydopa quinone AOC3 common genes common pathways 41565:[DB00399 DB09309] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09309|Kitasamycin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41566:[DB00399 DB00993] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 41567:[DB00399 DB01056] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0055085| transmembrane transport SCN5A;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0042493| response to drug ABCC1;CYP1A2 41568:[DB00399 DB00555] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0006810| transport GABRD;ABCC1;GABRA4;GABRA6;GABRB1;GABRB2;GABRA5;GABRA3;ABCB1;GABRG2;CACNA1E;GABRA1;GABRB3 GO:0008202| steroid metabolic process FDPS;UGT1A1 GO:0055085| transmembrane transport SLC22A2;ABCC1;CACNA1E;SCN2A;ABCB1 GO:0042493| response to drug ADORA2A;ABCC1;UGT1A1;ADRA1A;DRD2;DRD1;HTR2A;ABCB1;GABRG3 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;ABCC1 GO:0016032| viral reproduction FDPS;HTR2A 41569:[DB00399 DB11077] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways GO:0006629| lipid metabolic process FDPS;SULT1A1 GO:0006691| leukotriene metabolic process ABCC1;CYP4A11 GO:0008202| steroid metabolic process SULT1A1;FDPS 41570:[DB00399 DB11487] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41571:[DB00399 DB04896] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0042493| response to drug ABCC1;SLC6A2;SLC6A4;GRIN2A GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport GRIN2B;GRIN2A;GRIN2C;ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41572:[DB00399 DB01354] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0006810| transport GABRA1;GABRA4;GABRA6;GRIK2;ABCC1;GABRA3;GABRA5 41573:[DB00399 DB01255] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0006810| transport ABCC1;SLC15A1 GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0055085| transmembrane transport ABCC1;SLC15A1 GO:0006629| lipid metabolic process FDPS;CYP2D6 41574:[DB00399 DB01253] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01253|Ergometrine ADRA1A;CYP3A4;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ADRA1A;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41575:[DB00399 DB01202] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways GO:0055085| transmembrane transport CACNA1B;SV2A;ABCC1;ABCC2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport CACNA1B;ABCC1;ABCB1;ABCC2 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCB1;ABCC2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCC2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41576:[DB00399 DB00344] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;SLC6A2;SLC6A4;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC6A4;SLC6A2;ABCC1 GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006810| transport SLC6A2;ABCC1;ABCB1 41577:[DB00399 DB00007] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41578:[DB00399 DB06420] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06420|Annamycin TOP2A common genes common pathways 41579:[DB00399 DB09238] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4 GO:0042493| response to drug ABCC1;CYP1A1 GO:0006810| transport ABCC1;CACNB3;CACNB1;CACNB4;CACNA1I GO:0008202| steroid metabolic process CYP1A1;CYP2C19;CYP2D6;CYP2C9;CYP2B6;FDPS;CYP3A4 GO:0055085| transmembrane transport CACNA1C;CACNA1D;ABCC1;CACNA1S;CACNA1H;CACNA1G;CACNA1I;CACNA1F 41580:[DB00399 DB00301] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways GO:0006810| transport ABCC1;ABCB11 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB11;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41581:[DB00399 DB00255] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00255|Diethylstilbestrol ESR1;ESRRG;ESR2;ESRRA;ESRRB;NCOA2;NR1I2;AR;SHBG;COMT;CYP19A1;CYP3A4;CYP2C8;CYP2C9;CYP2E1;TTR;ABCG2;ABCB1;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0042493| response to drug COMT;ABCB1;CYP2E1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCG2;ABCC1;ABCB11;SLCO1B1;SLCO2B1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4;FDPS;NR1I2;CYP2C9 GO:0006810| transport AR;ABCB11;ABCG2;ABCC1;TTR;ABCB1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;NR1I2;ABCG2;ABCC1 41582:[DB00399 DB00455] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB11;ABCB1;KCNH2 GO:0006810| transport ABCB1;ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C8;CYP2C19 GO:0042493| response to drug ABCB1;ABCC1 41583:[DB00399 DB05077] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05077|SLV319 CNR1 common genes common pathways 41584:[DB00399 DB06963] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways 41585:[DB00399 DB00893] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways 41586:[DB00399 DB13874] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways GO:0042493| response to drug ABCC1;UGT1A1;ABCG2;CYP1A2;ABCB1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP2B6;CYP2C9;CYP2D6;CYP1A2;FDPS;CYP3A4;UGT2B7;UGT2B15;UGT1A1;CYP2C8;CYP2C19 GO:0055085| transmembrane transport ABCC1;ABCG2;SLCO1B1;SLC22A8;SLC22A6;SLC22A2;ABCB1;SLCO1B3 GO:0006629| lipid metabolic process UGT2B7;CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;ABCG2;ABCC1 41587:[DB00399 DB01764] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41588:[DB00399 DB06144] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug ABCC1;HTR2A;ADRA1A;DRD2;HTR2C GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0055085| transmembrane transport KCNH2;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0016032| viral reproduction FDPS;HTR2A 41589:[DB00399 DB00797] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A 41590:[DB00399 DB14072] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14072|Reversin 121 ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 41591:[DB00399 DB01136] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process PTGS1;CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2 GO:0016032| viral reproduction VCAM1;FDPS GO:0006810| transport ABCB1;ABCC1;GJA1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2;UGT1A1;CYP1A1;CYP2E1 GO:0055085| transmembrane transport ABCC1;GJA1;ABCB1;KCNH2 GO:0060326| cell chemotaxis ABCC1;VCAM1 GO:0042493| response to drug CYP2E1;ADRA1A;CYP1A1;ABCC1;UGT1A1;CYP1A2;ABCB1 41592:[DB00399 DB00717] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00717|Norethisterone PGR;CYP3A4;CYP3A5;CYP3A7;CYP2C19;ALB;SHBG;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5;CYP3A7;CYP2C19 GO:0006810| transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41593:[DB00399 DB01621] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;ABCC1 GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP2D6;CYP3A4 GO:0042493| response to drug DRD1;HTR2A;DRD2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;SLC22A1 GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41594:[DB00399 DB11471] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11471|Tilmicosin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41595:[DB00399 DB00425] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006810| transport GABRG2;GABRB3;GABRA1;ABCC1;GABRA3 GO:0008202| steroid metabolic process CYP2C19;CYP3A7;CYP3A5;CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 41596:[DB00399 DB11278] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug ADRA1A;ABCC1 41597:[DB00399 DB14502] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0016032| viral reproduction SLC20A2;FDPS GO:0055085| transmembrane transport SLC20A1;ABCC1;SLC20A2;SLC34A2;SLC34A3 GO:0006810| transport ABCC1;SLC20A1;SLC20A2 GO:0042493| response to drug SLC34A1;ABCC1 41598:[DB00399 DB03542] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways 41599:[DB00399 DB11979] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0055085| transmembrane transport SLCO1B1;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP2C8;FDPS;CYP2D6;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 41600:[DB00399 DB06510] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0042493| response to drug PPARG;CYP1A2;ABCC1;UGT1A1 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;FDPS;CYP1A2 GO:0006629| lipid metabolic process PPARA;PPARG;CYP1A2;FDPS 41601:[DB00399 DB07776] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP1B1 41602:[DB00399 DB00922] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0042493| response to drug PDE3A;KCNJ11;ABCC1 GO:0055085| transmembrane transport KCNJ11;ABCC1 GO:0006629| lipid metabolic process PDE3A;FDPS 41603:[DB00399 DB01176] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS GO:0008202| steroid metabolic process CYP2C9;SULT1E1;FDPS 41604:[DB00399 DB00962] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process TSPO;FDPS;CYP3A4;CYP3A5;CYP3A7 GO:0006810| transport GABRA1;ABCC1 GO:0042493| response to drug ABCC1;TSPO GO:0006694| steroid biosynthetic process TSPO;FDPS 41605:[DB00399 DB09328] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways GO:0006629| lipid metabolic process ELOVL4;CYP1A2;FDPS;ACAA1;FADS1 GO:0008202| steroid metabolic process CYP2E1;FDPS;CYP1A2 GO:0042493| response to drug ABCC1;CYP2E1;CYP1A2 41606:[DB00399 DB01026] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process CYP51A1;CYP11B1;UGT2B7;CYP3A4;CYP2C9;CYP2D6;CYP11A1;CYP1A2;FDPS GO:0016126| sterol biosynthetic process CYP51A1;FDPS GO:0042908| xenobiotic transport ABCC1;ABCB1;NR1I2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CYP51A1 GO:0008203| cholesterol metabolic process CYP51A1;FDPS;CYP11A1 GO:0006691| leukotriene metabolic process ABCC1;CYP4F2 GO:0042493| response to drug UGT1A1;ABCC1;CYP1A1;ABCB1;CYP1A2 GO:0006694| steroid biosynthetic process CYP19A1;FDPS;CYP11A1;CYP51A1;CYP21A2;CYP11B1 GO:0006810| transport ABCB1;ABCB11;AR;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;UGT1A1;CYP51A1;CYP3A5;CYP21A2;CYP1A1;UGT2B7;CYP3A7;CYP11B1;CYP1B1;CYP3A4;CYP2A6;CYP2D6;CYP2C9;CYP2B6;NR1I2;FDPS;CYP1A2;CYP11A1 GO:0055085| transmembrane transport ABCB1;KCNH2;ABCB11;SLCO1B1;ABCC1;SLCO1A2 GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;CYP51A1 41607:[DB00399 DB11751] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCC1 41608:[DB00399 DB01203] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;FDPS 41609:[DB00399 DB04911] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;FDPS GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP2C19 41610:[DB00399 DB06228] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06228|Rivaroxaban F10;CYP3A4;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042493| response to drug ABCB1;ABCC1;ABCG2 41611:[DB00399 DB11090] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCC1 41612:[DB00399 DB01097] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0055085| transmembrane transport ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP1A2 GO:0006810| transport ABCC1;ABCG2 GO:0042493| response to drug CYP1A2;ABCC1;ABCG2;DHODH;PTK2B GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP2C9;CYP1A2;FDPS 41613:[DB00399 DB00670] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00670|Pirenzepine CHRM1 common genes common pathways 41614:[DB00399 DB01169] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC2;ABCC1 GO:0008202| steroid metabolic process CYP1A1;CYP1B1;CYP3A4;FDPS GO:0006810| transport ABCC2;ABCB1;ABCC1 GO:0042493| response to drug ABCC2;ABCB1;CDKN1A;ABCC1;CYP1A1;CCND1;HDAC1;JUN GO:0099133| ABCC2;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0016032| viral reproduction HDAC1;MAPK1;PML;MAPK3;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41615:[DB00399 DB04878] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04878|Voglibose MGAM common genes common pathways 41616:[DB00399 DB00831] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A;DRD2;ABCB1;CYP1A2 GO:0055085| transmembrane transport ABCB1;ABCC1;CALM1 GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41617:[DB00399 DB00311] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways GO:0055085| transmembrane transport SLC22A6;ABCC1 41618:[DB00399 DB00308] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways GO:0006810| transport CACNB1;ABCC1;CACNG1 GO:0055085| transmembrane transport KCNH2;KCNH6;KCNJ11;ABCC1;CACNA1C;KCNH7 GO:0042493| response to drug ABCC1;KCNJ11 41619:[DB00399 DB09225] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS GO:0016032| viral reproduction HTR2A;FDPS GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP3A4 GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC6A2;SLC6A4 GO:0042493| response to drug SLC6A4;CYP1A2;ABCC1;SLC6A2;HTR2A;DRD1;DRD2 41620:[DB00399 DB09237] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;CACNA1C 41621:[DB00399 DB06762] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06762|Pinacidil CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41622:[DB00399 DB00570] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes ABCC1 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2 GO:0099133| ABCC6;ABCC1;ABCC2 GO:0042493| response to drug ABCB1;ABCC2;ABCC1;JUN;ABCC6 GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0006810| transport ABCB11;ABCC6;ABCC1;ABCC2;ABCB1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport ABCC6;ABCB11;SLCO1B1;ABCC1;ABCC2;ABCB1 41623:[DB00399 DB04348] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes ABCC1 common pathways GO:0006810| transport SLC10A1;SLC10A2;ABCC3;ABCC2;ABCB1;ABCB11;ABCG2;ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport SLC51B;ABCG2;ABCC1;SLCO1A2;SLCO3A1;SLCO2B1;SLC22A6;SLCO4A1;SLC22A8;ABCB11;SLCO1B1;ABCC10;ABCC11;ABCB1;ABCC2;SLCO1C1;SLC51A;SLC10A1;SLC10A2;ABCC3;ABCC4;SLC16A1;SLCO1B3 GO:0099133| ABCC4;ABCC3;ABCC2;ABCC11;ABCC10;ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC4;ABCC2;ABCB1;ABCG2;ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCC3;ABCB1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2;ABCB1;ABCC3 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process SLC16A1;FDPS;FABP6;CEL GO:0016032| viral reproduction SLC10A1;FDPS 41624:[DB00399 DB00463] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0042493| response to drug ABCC1;GABRG3 GO:0055085| transmembrane transport ABCC1;GRIK2 GO:0006810| transport GABRB3;GABRA1;GABRG2;GABRB2;GABRA5;GABRA3;GABRD;ABCC1;GABRA4;GABRA6;GRIK2;GABRB1 41625:[DB00399 DB00579] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways GO:0042493| response to drug SLC6A2;ABCC1;SLC6A3;SLC6A4 GO:0055085| transmembrane transport SLC18A2;SLC6A2;ABCC1;SLC6A3;SLC6A4 GO:0006810| transport ABCC1;SLC6A2 41626:[DB00399 DB04895] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04895|Pegaptanib NRP1 common genes common pathways 41627:[DB00399 DB00678] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4;UGT2B7 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0060326| cell chemotaxis AGTR1;ABCC1 GO:0042493| response to drug ABCB1;UGT1A1;ABCC1;SLC22A12 GO:0006810| transport ABCB11;ABCC1;ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;UGT2B17;UGT2B7;CYP3A4;CYP2C9;FDPS GO:0055085| transmembrane transport ABCB11;SLC22A6;SLC22A12;ABCC1;SLC2A9;ABCB1 41628:[DB00399 DB14538] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process CYP11B1;CYP11B2;FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0042493| response to drug ABCB1;ANXA1;HSD11B2;ABCG2;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP11B1;HSD3B1;CYP11B2 GO:0055085| transmembrane transport SLC22A8;SLCO1A2;ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP11B1;CYP2C8;CYP11B2;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1;ABCG2 41629:[DB00399 DB06283] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06283|Ziconotide CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41630:[DB00399 DB08819] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process FDPS;PTGS2 41631:[DB00399 DB01384] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41632:[DB00399 DB06712] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug CYP2E1;ABCC1 GO:0055085| transmembrane transport CACNA1C;CACNA1D;ABCC1;CACNA1S GO:0008202| steroid metabolic process FDPS;CYP2A6;CYP3A4;CYP2E1;CYP2C8;CYP2C19 41633:[DB00399 DB00627] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;SLC16A1;FDPS GO:0006855| drug transmembrane transport ABCC1;SLC22A5 GO:0042493| response to drug NNMT;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A5;SLC16A3;SLCO2B1;SLC5A8;SLC16A1 GO:0008202| steroid metabolic process FDPS;CYP2D6 41634:[DB00399 DB00401] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;CACNA1S;CACNA1C;CACNA1D;ABCB1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 41635:[DB00399 DB01054] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;CACNA1H;CACNA1S;ABCC1;ABCB11;CACNA1D;CACNA1C GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP3A4;FDPS GO:0006810| transport ABCC1;CACNG1;ABCB11;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41636:[DB00399 DB05983] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0016032| viral reproduction NFKBIA;FDPS 41637:[DB00399 DB09336] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways 41638:[DB00399 DB04100] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCC2 GO:0006810| transport ABCC2;ABCC1 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC1;ABCC2 GO:0006855| drug transmembrane transport ABCC2;ABCC1 41639:[DB00399 DB00126] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC23A1 GO:0042493| response to drug ABCC1;PAM GO:0006720| isoprenoid metabolic process GGPS1;PHYH 41640:[DB00399 DB01274] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS GO:0008202| steroid metabolic process CYP2C19;CYP2A6;CYP2C9;CYP2D6;FDPS 41641:[DB00399 DB09413] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09413|Monopotassium phosphate ALPI common genes common pathways 41642:[DB00399 DB00035] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process FDPS;PTGS1;PTGS2 41643:[DB00399 DB02745] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02745|Uridine LSM6;SLC29A1 common genes common pathways 41644:[DB00399 DB00669] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug HTR1B;ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCB1;SLCO1B1;SLCO1A2;ABCC1;ABCG2 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 41645:[DB00399 DB01151] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A5;ABCB1;SLC22A1;SLC22A3 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0042493| response to drug HTR2C;CYP1A2;ABCB1;SLC6A4;ADRA1A;DRD2;HTR2A;CYP2E1;SMPD1;SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A4;SLC22A4;ABCB1;SLC22A1;SLC22A3;ABCC1;SLC6A2;SLC22A5;SLC22A2 GO:0008202| steroid metabolic process CYP2D6;CYP2B6;FDPS;CYP1A2;CYP3A4;CYP2A6;CYP2E1;CYP2C19 GO:0006810| transport SLC6A2;ABCC1;ABCB1 41646:[DB00399 DB03506] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03506|9-Deazaadenine APRT common genes common pathways 41647:[DB00399 DB12119] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12119|Gevokizumab IL1B common genes common pathways 41648:[DB00399 DB06636] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 41649:[DB00399 DB00081] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FDPS;FCGR2B 41650:[DB00399 DB08049] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways GO:0042493| response to drug ABCC1;COMT 41651:[DB00399 DB11198] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 41652:[DB00399 DB00490] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4;CYP3A7;CYP3A5 GO:0042493| response to drug ABCB1;DRD2;ABCC1 41653:[DB00399 DB12474] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9;FDPS;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 41654:[DB00399 DB01043] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2 GO:0006810| transport GRIN2A;GRIN2B;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP2A6;FDPS;CYP2B6 GO:0055085| transmembrane transport ABCC1;SLC22A2 GO:0042493| response to drug DRD2;ABCC1;GRIN2A 41655:[DB00399 DB09194] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A4;SLC6A3;ABCC1;SLC6A2 GO:0042493| response to drug ABCC1;SLC6A2;DRD2;ADRA1A;SLC6A3;HTR2A;SLC6A4;HTR2C 41656:[DB00399 DB00968] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0042493| response to drug COMT;ABCC1 GO:0055085| transmembrane transport SLC15A1;ABCC1 GO:0006810| transport SLC15A1;ABCC1 41657:[DB00399 DB00910] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41658:[DB00399 DB01107] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRB2;GABRA3;GABRA5;GABRD;ABCC1;GABRA4;GABRA6;GABRB1 GO:0042493| response to drug GABRG3;ABCC1 41659:[DB00399 DB01076] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes ABCC1 common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP2D6;CYP3A4;UGT2B7;HMGCR GO:0034775| glutathione transmembrane transport ABCC1 GO:0016126| sterol biosynthetic process FDPS;HMGCR GO:0006810| transport ABCB11;ABCC1;ABCB1;ABCC2;ABCC5 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP2C9;CYP2B6;CYP3A4;UGT2B7;CYP3A7;CYP3A5;HMGCR;CYP2C8;CYP2C19;UGT1A1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008299| isoprenoid biosynthetic process GGPS1;FDPS;HMGCR GO:0055085| transmembrane transport ABCC4;SLCO1B3;ABCC2;ABCC5;ABCB1;SLCO2B1;SLCO1B1;ABCB11;ABCC1;SLCO1A2 GO:0045540| regulation of cholesterol biosynthetic process HMGCR;GGPS1;FDPS GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1;FDPS GO:0008203| cholesterol metabolic process HMGCR;FDPS GO:0099133| ABCC2;ABCC5;ABCC4;ABCC1 GO:0042493| response to drug ABCC1;UGT1A1;ABCC4;ABCB1;ABCC2 GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0006694| steroid biosynthetic process FDPS;HMGCR 41660:[DB00399 DB09073] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug CDK4;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41661:[DB00399 DB08816] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS 41662:[DB00399 DB00424] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways 41663:[DB00399 DB09045] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09045|Dulaglutide GLP1R common genes common pathways 41664:[DB00399 DB00706] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00706|Tamsulosin ADRA1A;ADRA1D;ADRA1B;CYP3A4;CYP2D6;ORM1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0042493| response to drug ADRA1A;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41665:[DB00399 DB06307] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06307|Apoptone BCL2 common genes common pathways GO:0042493| response to drug ABCC1;BCL2 GO:0055085| transmembrane transport BCL2;ABCC1 41666:[DB00399 DB01418] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01418|Acenocoumarol VKORC1;CYP2C9;CYP1A2;CYP2C19;CYP3A4;ALB;ORM1 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;CYP1A2;FDPS;CYP3A4 GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2C19 41667:[DB00399 DB12130] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A5;FDPS;CYP2B6 41668:[DB00399 DB00356] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0042493| response to drug CYP1A2;ABCC1;CYP1A1;CYP2E1 GO:0055085| transmembrane transport KCNMA1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2D6;CYP1A2;FDPS;CYP1A1;CYP2E1 41669:[DB00399 DB09039] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6;UGCG 41670:[DB00399 DB04620] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04620|Cycloleucine GRIN1 common genes common pathways 41671:[DB00399 DB06016] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0042493| response to drug DRD2;HTR2A;HTR2B;ABCC1;DRD3 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0016032| viral reproduction FDPS;HTR2A 41672:[DB00399 DB09289] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09289|Tianeptine GRIA1;OPRM1;HTR1A;DRD3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;DRD3 GO:0008202| steroid metabolic process FDPS;CYP3A4 41673:[DB00399 DB00322] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;FDPS GO:0042493| response to drug ABCC1;TYMS GO:0006629| lipid metabolic process FDPS;CYP2C9 41674:[DB00399 DB03664] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03664|UP5 CMPK1 common genes common pathways 41675:[DB00399 DB01216] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process SRD5A2;AKR1D1;CYP3A7;SRD5A1;CYP3A5;CYP3A4;FDPS GO:0042493| response to drug SRD5A1;ABCC1;SRD5A2 GO:0006694| steroid biosynthetic process FDPS;SRD5A1;SRD5A2 GO:0006629| lipid metabolic process SRD5A1;AKR1D1;SRD5A2;FDPS;CYP3A4 41676:[DB00399 DB06730] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41677:[DB00399 DB00191] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways GO:0042493| response to drug SLC6A3;MAOB;SLC6A2;ABCC1;CYP1A2;SLC6A4 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A3;SLC6A4 GO:0008202| steroid metabolic process FDPS;CYP1A2 GO:0006810| transport ABCC1;SLC6A2 GO:0006629| lipid metabolic process CYP1A2;FDPS 41678:[DB00399 DB06650] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06650|Ofatumumab MS4A1 common genes common pathways 41679:[DB00399 DB00371] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug ABCC1;CYP2E1;GABRG3 GO:0008202| steroid metabolic process FDPS;CYP2C19;CYP2E1 GO:0006810| transport GABRA3;GABRA5;GABRB2;ABCC1;GABRD;GABRB1;GABRA4;GABRA6;GABRA1;GABRB3;GABRG2 41680:[DB00399 DB06684] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC6A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0042493| response to drug SLC6A4;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS 41681:[DB00399 DB00530] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;UGT1A1;ABCC1;ABCG2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP1A1;CYP3A5;CYP1B1;CYP3A4;NR1I2;CYP2D6;CYP1A2;FDPS GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0055085| transmembrane transport ABCB1;SLCO2B1;ABCG2;ABCC1 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport NR1I2;ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 41682:[DB00399 DB07789] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways 41683:[DB00399 DB01089] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01089|Deserpidine SLC18A2 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC18A2 41684:[DB00399 DB13166] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13166|Zofenopril ACE common genes common pathways 41685:[DB00399 DB01223] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;PDE3A GO:0042493| response to drug CYP1A2;ABCC1;HDAC2;PDE3A;CYP2E1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2C19;CYP2E1 41686:[DB00399 DB00108] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0016032| viral reproduction FCGR2B;FDPS;ICAM1 GO:0042493| response to drug ICAM1;ABCC1 41687:[DB00399 DB09236] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport CACNA1C;CACNA1D;ABCC1;CACNA1S;CACNA1F GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport CACNB1;CACNB3;ABCC1;CACNB4 41688:[DB00399 DB09070] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0006694| steroid biosynthetic process HSD3B2;HSD3B1;FDPS GO:0008202| steroid metabolic process SULT1A1;FDPS;STS GO:0006629| lipid metabolic process STS;FDPS;SULT1A1 41689:[DB00399 DB04905] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;CYP1A1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP1A1;CYP3A4;FDPS;CYP2D6 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41690:[DB00399 DB00487] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process FDPS;CYP1A2 41691:[DB00399 DB00682] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00682|Warfarin VKORC1;NR1I2;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2C8;CYP2C18;CYP1A1;ALB;ORM1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;NR1I2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9 GO:0008202| steroid metabolic process FDPS;CYP1A2;NR1I2;CYP2C9;CYP3A4;CYP1A1;CYP2C19;CYP2C8 GO:0042493| response to drug CYP1A2;CYP1A1;ABCC1 41692:[DB00399 DB05920] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05920|RTA 744 TOP2A common genes common pathways 41693:[DB00399 DB11397] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways GO:0042493| response to drug BCHE;ABCC1 41694:[DB00399 DB01589] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0006810| transport GABRB3;GABRA1;GABRG2;GABRB2;GABRA5;GABRA3;GABRD;GABRR2;ABCC1;GABRA4;GABRA6;GABRR1;GABRB1 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2C9;CYP2B6;FDPS GO:0042493| response to drug GABRG3;ABCC1 41695:[DB00399 DB00104] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41696:[DB00399 DB01064] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0016032| viral reproduction FDPS;MAPK1;PIK3R1 GO:0042493| response to drug ABCC1;CYP1A1;SOD1 GO:0008202| steroid metabolic process CYP1A1;FDPS 41697:[DB00399 DB09280] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A4;CYP2B6;CYP2C9;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1;CFTR GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CFTR GO:0042493| response to drug ABCB1;ABCC1 GO:0099133| CFTR;ABCC1 41698:[DB00399 DB00633] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;CYP1A1;CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP1A2;CYP1A1;CYP2E1 41699:[DB00399 DB01349] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0060326| cell chemotaxis ABCC1;AGTR1 GO:0008202| steroid metabolic process FDPS;CYP3A4 41700:[DB00399 DB00471] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways GO:0006691| leukotriene metabolic process ABCC1;ALOX5 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;FDPS;CYP2A6;CYP3A4 GO:0055085| transmembrane transport ABCC1;SLCO2B1 GO:0006629| lipid metabolic process PTGS1;FDPS;CYP2C9;CYP3A4 41701:[DB00399 DB01587] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process TSPO;FDPS;CYP3A4 GO:0006810| transport GABRB1;ABCC1;GABRD;GABRA1;ABCB1 GO:0006694| steroid biosynthetic process FDPS;TSPO GO:0042493| response to drug TSPO;ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41702:[DB00399 DB13500] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13500|Otilonium CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41703:[DB00399 DB09154] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways GO:0006810| transport ABCC1;SLC13A2 GO:0055085| transmembrane transport SLC13A2;SLC25A21;ABCC1;SLC13A5;SLC25A1 41704:[DB00399 DB01231] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways 41705:[DB00399 DB00917] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP11A1 GO:0006855| drug transmembrane transport ABCC1;SLC22A2 GO:0006694| steroid biosynthetic process FDPS;CYP11A1;CYP19A1 GO:0042493| response to drug ABCC1;ABCC4 GO:0099133| ABCC1;ABCC5;ABCC4 GO:0008203| cholesterol metabolic process CYP11A1;FDPS GO:0055085| transmembrane transport SLCO4A1;SLC22A7;SLCO1B1;SLC22A8;SLCO2B1;SLC22A2;SLC22A6;SLC22A11;SLCO3A1;SLCO1A2;SLC51B;ABCC1;SLCO2A1;ABCC4;ABCC5;SLC51A;SLCO1C1 GO:0008202| steroid metabolic process CYP11A1;FDPS GO:0006810| transport ABCC5;ABCC1 41706:[DB00399 DB01583] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0016032| viral reproduction FDPS;SLC10A1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLCO1A2;SLCO4A1;SLC22A8;SLCO1B1;SLCO4C1;ABCB1;SLCO1C1;SLC16A10;SLC10A1;SLC16A2;SLCO1B3 GO:0006810| transport ABCC1;SLC10A1;TTR;SLC16A2;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;FDPS 41707:[DB00399 DB00331] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0006629| lipid metabolic process PRKAB1;FDPS GO:0006855| drug transmembrane transport SLC47A2;SLC22A1;SLC47A1;SLC22A3;ABCC1;SLC22A2 GO:0055085| transmembrane transport ABCC1;SLC22A2;SLC29A4;SLC22A1;SLC47A2;SLC22A3;SLC47A1 41708:[DB00399 DB07700] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0008202| steroid metabolic process AKR1C3;FDPS 41709:[DB00399 DB04951] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0042493| response to drug ABCC1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS 41710:[DB00399 DB09230] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways GO:0006810| transport CACNB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41711:[DB00399 DB00850] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 GO:0042493| response to drug ABCC1;DRD1;DRD2;CYP1A2 GO:0055085| transmembrane transport CALM1;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP3A4;CYP2C19;CYP2C8 41712:[DB00399 DB04957] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A1;CYP3A5 GO:0055085| transmembrane transport KCNQ1;ABCC1;KCNH2 GO:0042493| response to drug ABCC1;CYP1A1 41713:[DB00399 DB05679] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways 41714:[DB00399 DB01456] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01456|5-androstenedione CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41715:[DB00399 DB05514] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05514|Cobiprostone CLCN2 common genes common pathways GO:0006810| transport ABCC1;CLCN2 GO:0055085| transmembrane transport ABCC1;CLCN2 41716:[DB00399 DB01559] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP2B6;CYP3A4 GO:0006810| transport GABRG2;GABRB3;GABRA1;GABRB1;GABRR1;ABCC1;GABRR2;GABRD;GABRA3;GABRA5;GABRB2 GO:0042493| response to drug GABRG3;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41717:[DB00399 DB09091] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0042493| response to drug HDAC2;ABCC1 41718:[DB00399 DB04794] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;CYP2E1 GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0008202| steroid metabolic process CYP2E1;CYP2B6;FDPS;CYP3A4 41719:[DB00399 DB12141] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;ABCG2;SLC47A1;SLC22A1;ABCB1 GO:0042493| response to drug ABCB1;HTR1B;HTR2C;ABCG2;HTR2B;ABCC1;HTR2A GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1;SLC22A1;SLC47A1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0016032| viral reproduction AXL;HTR2A;FDPS 41720:[DB00399 DB00769] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41721:[DB00399 DB00252] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9;CYP11B1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2 GO:0042908| xenobiotic transport ABCC1;ABCB1;NR1I2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006694| steroid biosynthetic process CYP11B1;FDPS GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug ABCC1;UGT1A1;ABCB1;ABCC2 GO:0055085| transmembrane transport SLCO1C1;ABCC2;ABCB1;SCN3A;SCN1A;ABCC1;SCN5A GO:0006810| transport ABCB1;ABCC2;ABCC1 GO:0008202| steroid metabolic process CYP2D6;NR1I2;CYP2B6;CYP2C9;FDPS;CYP3A4;CYP3A5;CYP11B1;CYP3A7;CYP2C19;CYP2C8;UGT1A1 41722:[DB00399 DB00078] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FDPS;FCGR2B 41723:[DB00399 DB09140] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways 41724:[DB00399 DB04946] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2E1;CYP3A7;CYP3A5 GO:0042493| response to drug DRD3;DRD2;ADRA1A;HTR2A;CYP2E1;DRD1;ABCC1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41725:[DB00399 DB11614] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9 GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP2D6;CYP3A4;CYP2C19 41726:[DB00399 DB14064] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 41727:[DB00399 DB06814] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06814|Protokylol ADRB2 common genes common pathways 41728:[DB00399 DB06145] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06145|Spiramycin rplC;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41729:[DB00399 DB00773] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes ABCC1 common pathways GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4;PTGS1;PTGS2 GO:0006855| drug transmembrane transport ABCC3;ABCC2;ABCB1;ABCC1;ABCG2 GO:0042908| xenobiotic transport ABCC3;ABCB1;ABCC1;ABCG2 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCG2;UGT1A1;ABCC1;PTGS2;ABCC6;CYP2E1;ABCB1;ABCC2;CYP1A2 GO:0099133| ABCC10;ABCC6;ABCC1;ABCC3;ABCC2 GO:0060326| cell chemotaxis ABCC1 GO:0055085| transmembrane transport ABCC1;ABCG2;ABCC6;ABCC10;ABCC2;ABCB1;ABCC3 GO:0006810| transport ABCC1;ABCG2;ABCC6;ABCC2;ABCB1;ABCC3 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;UGT1A1;CYP2C8;CYP1A2;FDPS;CYP3A4 41730:[DB00399 DB00794] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0042493| response to drug CYP1A2;GABRG3;UGT1A1;ABCC1 GO:0055085| transmembrane transport ABCC1;GRIK2 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP1A2;FDPS;CYP2B6;CYP2C9;CYP3A4 GO:0006810| transport GABRG2;GABRA1;GABRB3;ABCC1;GABRD;GABRB1;GABRA4;GABRA6;GRIK2;GABRA3;GABRA5;GABRB2 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP3A4 41731:[DB00399 DB00178] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport ABCC1;SLC15A2;SLC15A1 GO:0055085| transmembrane transport SLC15A2;ABCC1;SLC15A1 GO:0042493| response to drug BCHE;ABCC1 41732:[DB00399 DB00592] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006810| transport ABCC1;GABRB3 41733:[DB00399 DB09227] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CACNA1C;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41734:[DB00399 DB00925] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;ABCC1;SLC22A3;SLC22A1 GO:0055085| transmembrane transport SLC22A3;SLC22A1;SLC22A2;CALM1;ABCC1 GO:0042493| response to drug ABCC1;ADRA1A 41735:[DB00399 DB12418] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12418|Saccharin CA3 common genes common pathways 41736:[DB00399 DB00449] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A;BCHE 41737:[DB00399 DB12061] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0042493| response to drug DRD3;DRD2;ABCC1 41738:[DB00399 DB06215] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways 41739:[DB00399 DB09167] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0042493| response to drug ADRA1A;HTR2A;SLC6A2;ABCC1;CYP1A2;SLC6A4 GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A4 GO:0006810| transport SLC6A2;ABCC1 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP1A2;FDPS;CYP2C19 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP1A2;FDPS 41740:[DB00399 DB00446] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC22A6 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A7;CYP3A5;CYP3A4;FDPS GO:0016032| viral reproduction FDPS;CD55 GO:0006629| lipid metabolic process CYP3A4;FDPS 41741:[DB00399 DB01973] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 41742:[DB00399 DB00373] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP2D6;FDPS GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;FDPS 41743:[DB00399 DB09462] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0008203| cholesterol metabolic process PPARD;FDPS GO:0042493| response to drug CYP2E1;ABCC1;TGFBR2 GO:0008202| steroid metabolic process FDPS;CYP2E1 GO:0055085| transmembrane transport ABCC1;ITPR1 GO:0006629| lipid metabolic process FDPS;PPARD;HPGDS;ISYNA1;PLA2G2E 41744:[DB00399 DB02508] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes FDPS common pathways GO:0045337| farnesyl diphosphate biosynthetic process FDPS;GGPS1 GO:0006695| cholesterol biosynthetic process GGPS1;FDPS GO:0008203| cholesterol metabolic process FDPS GO:0006694| steroid biosynthetic process FDPS GO:0008202| steroid metabolic process FDPS GO:0033384| geranyl diphosphate biosynthetic process FDPS;GGPS1 GO:0008299| isoprenoid biosynthetic process FDPS;GGPS1 GO:0045540| regulation of cholesterol biosynthetic process FDPS;GGPS1 GO:0006629| lipid metabolic process FDPS GO:0016126| sterol biosynthetic process FDPS GO:0016032| viral reproduction FDPS 41745:[DB00399 DB00319] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC22A6;SLC22A8 41746:[DB00399 DB00393] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0055085| transmembrane transport CACNA1S;ABCC1;CACNA1D;CACNA1C;CACNA1F GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP3A5 GO:0006810| transport CACNB3;ABCC1;CACNB1;CACNB4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41747:[DB00399 DB00716] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0060326| cell chemotaxis FPR1;ABCC1 41748:[DB00399 DB00825] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0055085| transmembrane transport CACNA1D;CACNA1C;TRPM8;CACNA1S;ABCC1;TRPV3;CACNA1F;TRPA1 GO:0006810| transport CACNB3;ABCC1;CACNB1;CACNB4 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0042493| response to drug ABCC1;TRPA1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41749:[DB00399 DB01105] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways GO:0042493| response to drug ABCC1;SLC6A2;SLC6A3;SLC6A4 GO:0055085| transmembrane transport ABCC1;SLC6A2;SLC6A3;SLC6A4 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;SLC6A2 GO:0006629| lipid metabolic process CYP3A4;FDPS 41750:[DB00399 DB00030] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0006629| lipid metabolic process FDPS;LRP2 GO:0016032| viral reproduction RB1;IDE;FDPS GO:0060326| cell chemotaxis NOV;ABCC1 41751:[DB00399 DB00207] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 41752:[DB00399 DB01128] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4;CYP2C19 GO:0006810| transport ABCC1;AR GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4 41753:[DB00399 DB06290] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCG2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2 GO:0016032| viral reproduction SLC10A1;FDPS GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS GO:0006810| transport ABCC2;ABCB1;SLC10A1;ABCG2;ABCC1;ABCB11 GO:0055085| transmembrane transport SLCO1B3;SLC10A1;ABCC2;ABCB1;SLCO1B1;ABCB11;SLCO2B1;ABCC1;ABCG2 GO:0042493| response to drug CYP1A2;ABCB1;ABCC2;ABCG2;ABCC1 GO:0099133| ABCC2;ABCC1 41754:[DB00399 DB06287] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP3A5;CYP3A7 GO:0006810| transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 41755:[DB00399 DB13884] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways 41756:[DB00399 DB11995] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042493| response to drug ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP2C8;FDPS;CYP2C9 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC22A8;ABCG2;ABCC1 41757:[DB00399 DB06457] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06457|Tecastemizole KCNH2 common genes common pathways GO:0055085| transmembrane transport ABCC1;KCNH2 41758:[DB00399 DB07117] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 41759:[DB00399 DB00829] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00829|Diazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9;CYP2B6;CYP2C18;CYP2C8;PTGS1;CYP2E1;ALB;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process PTGS1;CYP2C9;FDPS;CYP3A4 GO:0006810| transport GABRA3;GABRA5;GABRB2;GABRB1;GABRA6;GABRR1;GABRA4;GABRR2;ABCC1;GABRD;GABRA1;GABRB3;GABRG2;ABCB1 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A7;CYP2C19;CYP2C8;CYP2C9;CYP2B6;TSPO;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug GABRG3;ABCB1;TSPO;ABCC1;CYP2E1 GO:0006694| steroid biosynthetic process TSPO;FDPS 41760:[DB00399 DB00734] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0016032| viral reproduction FDPS;HTR2A GO:0042493| response to drug DRD3;HTR2C;ABCC1;DRD2;ADRA1A;HTR2A;DRD1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP3A7;CYP3A5 41761:[DB00399 DB08794] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08794|Ethyl biscoumacetate GLUL;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41762:[DB00399 DB05750] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05750|AVE-1625 CNR1 common genes common pathways 41763:[DB00399 DB01147] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC15A2;SLC22A6;SLC15A1 GO:0006810| transport SLC15A2;ABCC1;SLC15A1 41764:[DB00399 DB00120] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC16A10 GO:0006810| transport ABCC1;SLC7A8 GO:0042493| response to drug ABCC1;TH 41765:[DB00399 DB01267] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01267|Paliperidone HTR2A;DRD2;HRH1;ADRA1A;ADRA1B;DRD4;HTR1D;DRD3;HTR2C;ADRA2A;ADRA2B;ADRA2C;HTR1A;DRD1;HTR7;CYP3A4;CYP2D6;CYP3A5;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP3A5 GO:0042493| response to drug DRD3;ABCB1;HTR2C;ABCC1;DRD2;ADRA1A;HTR2A;DRD1 41766:[DB00399 DB00869] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 41767:[DB00399 DB11636] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11636|Nomegestrol CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41768:[DB00399 DB00998] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;HTR1B;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 41769:[DB00399 DB12089] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41770:[DB00399 DB07173] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways 41771:[DB00399 DB00539] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug CYP1A1;ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41772:[DB00399 DB09061] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes ABCC1 common pathways GO:0008203| cholesterol metabolic process FDPS;CAT;HMGCR GO:0006695| cholesterol biosynthetic process HMGCR;FDPS;GGPS1 GO:0006694| steroid biosynthetic process FDPS;HMGCR;CYP17A1 GO:0060326| cell chemotaxis ABCC1 GO:0042493| response to drug CAT;CYP1A2;TRPA1;PPARG;SOD1;HTR2A;CYP1A1;PTGS2;ABCG2;SMPD1;ABCC1 GO:0006691| leukotriene metabolic process ALOX15;ALOX5;ABCC1 GO:0099133| ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP17A1;CYP1A1;HMGCR;CYP2C19;FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP1B1 GO:0006810| transport TRPV2;ABCG2;ABCC1;TRPV1;CACNA1I GO:0055085| transmembrane transport TRPV2;TRPV3;CACNA1H;TRPM8;ABCG2;TRPV4;ABCC1;TRPV1;TRPA1;VDAC1;CACNA1I;CACNA1G GO:0045540| regulation of cholesterol biosynthetic process HMGCR;FDPS;GGPS1 GO:0008299| isoprenoid biosynthetic process GGPS1;FDPS;HMGCR GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0006629| lipid metabolic process DAGLA;TRPV1;PTGS1;NAPEPLD;PTGS2;HMGCR;NAAA;CYP2C9;ALOX15;CYP2D6;CYP1A2;FDPS;PPARG;PLA2G1B;CYP3A4;GPX1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0016032| viral reproduction HTR2A;FDPS;VDAC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 41773:[DB00399 DB01873] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41774:[DB00399 DB11135] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways 41775:[DB00399 DB00950] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00950|Fexofenadine HRH1;ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3;SLC22A8 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport SLC22A8;SLCO1B1;SLCO2B1;SLCO1A2;ABCC1;SLCO1B3;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 41776:[DB00399 DB00397] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0042493| response to drug ABCC1;DRD1 41777:[DB00399 DB00908] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00908|Quinidine SCN5A;KCNK1;KCNK6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A7;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP2B6;CYP2C9;CYP2C8;ORM1;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A8;ABCC2;SLC22A4;SLCO1B1;ABCB11 common genes common pathways GO:0055085| transmembrane transport SLC22A1;ABCB1;ABCC2;SLC22A4;KCNH2;SLC22A2;SLCO1B1;SLC22A5;ABCB11;SLC22A8;ABCC1;SLCO1A2;SCN5A GO:0006810| transport ABCC2;ABCB1;ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP1A1;CYP2C8;CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP3A4 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCB1;ABCC2;CYP1A2;ABCC1;CYP2E1;CYP1A1;ADRA1A GO:0006855| drug transmembrane transport SLC22A2;SLC22A5;ABCC1;ABCC2;ABCB1;SLC22A1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 41778:[DB00399 DB05012] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05012|XEN2174 SLC6A2 common genes common pathways GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport ABCC1;SLC6A2 GO:0042493| response to drug SLC6A2;ABCC1 41779:[DB00399 DB00728] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCC1;SLC22A1 GO:0006855| drug transmembrane transport SLC22A1;ABCC1 41780:[DB00399 DB09047] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways 41781:[DB00399 DB00643] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP1A1 GO:0042493| response to drug ABCC1;CYP1A1 41782:[DB00399 DB00612] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 41783:[DB00399 DB00213] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;ABCG2 GO:0055085| transmembrane transport SLCO1B1;ABCG2;ABCC1;ABCB1 GO:0006810| transport ATP4A;ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 41784:[DB00399 DB08922] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0042493| response to drug HTR2A;DRD2;ADRA1A;CYP1A1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C8;CYP1A1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0016032| viral reproduction FDPS;HTR2A 41785:[DB00399 DB01576] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC18A2;ABCC1;SLC6A2;SLC6A3 GO:0042493| response to drug SLC6A2;ABCC1;ADRA1A;SLC6A3 41786:[DB00399 DB01068] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0006694| steroid biosynthetic process FDPS;TSPO GO:0042493| response to drug CYP2E1;ABCC1;TSPO;GABRG3 GO:0006810| transport GABRA5;GABRA3;GABRB2;ABCC1;GABRD;GABRB1;GABRA6;GABRA4;GABRA1;GABRB3;GABRG2 GO:0008202| steroid metabolic process CYP3A4;FDPS;TSPO;NR1I2;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042908| xenobiotic transport ABCC1;NR1I2 41787:[DB00399 DB00647] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00647|Dextropropoxyphene OPRM1;OPRD1;OPRK1;CES1;CYP3A4;CYP2D6;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;FDPS;CYP2D6 GO:0006695| cholesterol biosynthetic process CES1;GGPS1;FDPS 41788:[DB00399 DB11598] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11598|Antithrombin III human SERPINC1 common genes common pathways 41789:[DB00399 DB02236] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02236|Glycinamide Ribonucleotide GART common genes common pathways 41790:[DB00399 DB00270] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB11;CACNA1D;CACNA1C;CACNA1S;ABCC1;CACNA1H GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCB11;ABCC1 41791:[DB00399 DB08971] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08971|Fluocortolone CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 41792:[DB00399 DB13488] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13488|Bencyclane CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41793:[DB00399 DB00741] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042493| response to drug ABCG2;ABCC1;HSD11B2;ANXA1;ABCB1 GO:0006694| steroid biosynthetic process FDPS;CYP11B2;CYP11B1;HSD3B1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP11B1;CYP3A7;CYP3A5;CYP11B2;CYP2C8 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport SLCO1A2;ABCC1;ABCG2;SLC22A8;ABCB1 41794:[DB00399 DB08872] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways GO:0006810| transport SLC5A6;ABCC1 GO:0055085| transmembrane transport SLC5A6;ABCC1;SLC5A8 41795:[DB00399 DB06421] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06421|Declopramide TOP2A;TOP2B common genes common pathways 41796:[DB00399 DB00233] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0006629| lipid metabolic process PLA2G2E;FDPS;PTGS2 GO:0006691| leukotriene metabolic process ALOX5;ABCC1 GO:0042493| response to drug ABCC1;PTGS2;CHUK 41797:[DB00399 DB05155] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05155|CR665 OPRK1 common genes common pathways 41798:[DB00399 DB09080] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09080|Olodaterol ADRB2;CYP2C9;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP2C8 GO:0006629| lipid metabolic process CYP2C9;FDPS 41799:[DB00399 DB00561] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00561|Doxapram KCNK3;KCNK9 common genes common pathways GO:0042493| response to drug ABCC1;KCNK3 41800:[DB00399 DB01357] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01357|Mestranol ESR1;CYP2C9;CYP3A4;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2C9;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4 41801:[DB00399 DB06654] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06654|Safinamide MAOB;MAOA;CYP3A4;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2E1;CYP3A5;ABCG2;SLCO3A1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 GO:0042493| response to drug CYP2E1;MAOB;CYP1A1;ABCC1;ABCG2;CYP1A2 GO:0006810| transport ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2B6;CYP2C9;FDPS;CYP1A2;CYP2C19;CYP3A5;CYP1A1;CYP2E1 GO:0055085| transmembrane transport ABCG2;ABCC1;SLCO3A1 41802:[DB00399 DB00613] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00613|Amodiaquine HNMT;CYP2C8;CYP1A1;CYP1B1;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;CYP1A1;ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;FDPS;CYP1B1;CYP1A1;CYP2C8 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41803:[DB00399 DB01612] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01612|Amyl Nitrite NPR1;ALDH2 common genes common pathways 41804:[DB00399 DB09220] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09220|Nicorandil ABCC9 common genes common pathways GO:0042493| response to drug ABCC9;ABCC1 GO:0099133| ABCC1;ABCC9 GO:0055085| transmembrane transport ABCC9;ABCC1 41805:[DB00399 DB14518] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14518|Aluminum acetate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0042493| response to drug ATP1A1;ABCC1 GO:0008203| cholesterol metabolic process APP;FDPS 41806:[DB00399 DB00867] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00867|Ritodrine ADRB2;PGD common genes common pathways 41807:[DB00399 DB11901] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11901|Apalutamide AR;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C19;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLC22A2;SLC22A8;SLC47A2 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport SLC22A2;ABCC1;ABCG2;ABCB1;SLC47A2 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP3A4;CYP2C8;CYP2C19 GO:0006810| transport GABRG2;ABCB1;GABRB3;GABRA1;GABRB1;GABRA4;GABRA6;ABCG2;ABCC1;GABRD;AR;GABRA5;GABRA3;GABRB2 GO:0055085| transmembrane transport SLCO1B1;SLC22A8;SLC22A2;ABCG2;ABCC1;SLC47A2;ABCB1 GO:0042493| response to drug GABRG3;ABCB1;ABCG2;ABCC1 41808:[DB00399 DB01586] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01586|Ursodeoxycholic acid AKR1C2;NR1H4;CYP2E1;ABCB11;SLCO1A2;ABCC2;ABCC4;SLC10A2;SLC10A1 common genes common pathways GO:0006629| lipid metabolic process AKR1C2;FDPS GO:0016032| viral reproduction FDPS;SLC10A1 GO:0006855| drug transmembrane transport ABCC2;ABCC1 GO:0042493| response to drug CYP2E1;ABCC1;ABCC4;ABCC2 GO:0099133| ABCC1;ABCC2;ABCC4 GO:0008202| steroid metabolic process CYP2E1;AKR1C2;FDPS GO:0006810| transport ABCC2;SLC10A2;SLC10A1;ABCC1;ABCB11 GO:0055085| transmembrane transport SLCO1A2;ABCC1;ABCB11;ABCC2;ABCC4;SLC10A2;SLC10A1 41809:[DB00399 DB05495] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05495|PG-530742 MMP9 common genes common pathways 41810:[DB00399 DB11633] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11633|Isavuconazole KCNH2;CACNA1C;KCNJ6;KCNJ9;KCNJ11;KCNA5;KCND3;KCNQ1;SCN5A;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A9;UGT1A8;ABCB1;ABCG2;SLC22A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;ABCG2;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9 GO:0055085| transmembrane transport KCNQ1;SLC22A2;CACNA1C;KCNA5;ABCG2;ABCC1;SCN5A;KCNJ11;ABCB1;KCND3;KCNH2 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;UGT1A8;CYP2C9;CYP2B6;CYP2D6;FDPS;CYP2C19;CYP2C8;CYP3A5 GO:0042493| response to drug ABCB1;KCNJ11;ABCG2;ABCC1 41811:[DB00399 DB01229] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01229|Paclitaxel TUBB1;BCL2;NR1I2;MAP4;MAP2;MAPT;CYP3A5;CYP3A7;CYP2C8;CYP3A4;CYP19A1;CYP1B1;ABCB11;ABCB1;ABCC1;ABCC10;SLCO1B3;ABCG2;ABCC2 common genes ABCC1 common pathways GO:0006810| transport ABCC1;ABCG2;ABCB11;ABCB1;ABCC2 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP1B1;CYP3A4;NR1I2;FDPS;CYP2C8;CYP3A5;CYP3A7 GO:0055085| transmembrane transport BCL2;SLCO1B3;ABCB1;ABCC2;ABCC10;ABCB11;ABCC1;ABCG2 GO:0060326| cell chemotaxis ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC1;ABCG2;ABCC2;ABCB1;BCL2 GO:0099133| ABCC1;ABCC10;ABCC2 GO:0042908| xenobiotic transport NR1I2;ABCB1;ABCC1;ABCG2 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1;ABCG2 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 41812:[DB00399 DB12267] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12267|Brigatinib ALK;EGFR;ABL1;IGF1R;FLT3;INSR;MET;ERBB4;ERBB2;CYP2C8;CYP3A4;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB5;ABCG2;SLC22A1;SLC47A1;SLC47A2 common genes common pathways GO:0055085| transmembrane transport SLC47A1;SLC22A1;SLC47A2;ABCB5;ABCG2;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5;CYP3A7;CYP2C8 GO:0006810| transport ABCC1;ABCG2 GO:0042493| response to drug ABCG2;ABCC1 GO:0006855| drug transmembrane transport SLC22A1;SLC47A2;SLC47A1;ABCG2;ABCC1;ABCB5 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB5 GO:0006629| lipid metabolic process FDPS;CYP3A4 41813:[DB00399 DB03866] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03866|Prostaglandin G2 PTGS2 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process PTGS2;FDPS 41814:[DB00399 DB09074] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09074|Olaparib PARP1;PARP2;PARP3;CYP3A4;CYP2B6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP2B6;CYP3A4 41815:[DB00399 DB00411] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00411|Carbamoylcholine CHRM1;CHRM2;CHRNA2;ACHE;CHRM3;CHRM4;PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;FDPS 41816:[DB00399 DB00918] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00918|Almotriptan HTR1B;HTR1D;MAOA;CYP3A4;CYP2D6;FMO3;CYP2C19;CYP2E1;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0042493| response to drug HTR1B;ABCC1;CYP2E1 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4;CYP2E1;CYP2C19;CYP2C8 41817:[DB00399 DB00957] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00957|Norgestimate PGR;ESR1;AR;CYP3A4;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCC2 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCC2;ABCC1;AR GO:0055085| transmembrane transport ABCC2;ABCC1 GO:0042493| response to drug ABCC2;ABCC1 GO:0099133| ABCC2;ABCC1 41818:[DB00399 DB04860] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04860|Isatoribine TLR7 common genes common pathways 41819:[DB00399 DB00841] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00841|Dobutamine ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;ESR1;COMT common genes common pathways GO:0042493| response to drug COMT;ADRA1A;ABCC1 41820:[DB00399 DB11817] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11817|Baricitinib JAK1;JAK2;PTK2B;JAK3;CYP3A4;SLC22A8;ABCG2;SLC47A2;SLC22A6;SLC22A2;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC1;ABCG2;PTK2B GO:0055085| transmembrane transport ABCG2;ABCC1;SLC22A2;SLC22A6;SLC22A8;SLC47A2;SLCO1B3 GO:0006810| transport ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCG2;SLC22A2;SLC47A2 GO:0042908| xenobiotic transport ABCG2;ABCC1 41821:[DB00399 DB01214] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01214|Metipranolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0008202| steroid metabolic process FDPS;CYP2D6 41822:[DB00399 DB08808] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08808|Bupranolol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006629| lipid metabolic process CYP2D6;FDPS 41823:[DB00399 DB01309] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01309|Insulin Glulisine INSR common genes common pathways 41824:[DB00399 DB00040] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00040|Glucagon GCGR;GLP2R;GLP1R common genes common pathways 41825:[DB00399 DB00309] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00309|Vindesine TUBB1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41826:[DB00399 DB11988] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11988|Ocrelizumab MS4A1 common genes common pathways 41827:[DB00399 DB09102] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09102|Daclatasvir CYP3A5;CYP3A4;CYP3A43;CYP3A7;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;ABCG2 GO:0055085| transmembrane transport ABCG2;ABCC1;SLCO1B1;ABCB1;SLCO1B3 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP3A7;CYP3A5 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 41828:[DB00399 DB05018] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05018|Migalastat GLA;UGT1A1 common genes common pathways GO:0042493| response to drug UGT1A1;ABCC1 GO:0008202| steroid metabolic process FDPS;UGT1A1 41829:[DB00399 DB00674] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00674|Galantamine ACHE;CHRNA1;CHRNB1;CHRND;CHRNG;CHRNE;CHRNA2;CHRNA3;CHRNA4;CHRNA5;CHRNA6;CHRNA7;CHRNA9;CHRNA10;CHRNB2;CHRNB3;CHRNB4;BCHE;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0006810| transport ABCC1;CHRNA6;CHRNA1;CHRND;CHRNG;CHRNB3;CHRNE GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0042493| response to drug ABCC1;BCHE 41830:[DB00399 DB06153] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06153|Pizotifen CHRM1;CHRM2;CHRM3;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;UGT2B10 common genes common pathways GO:0006629| lipid metabolic process UGT2B10;FDPS GO:0016032| viral reproduction HTR2A;FDPS GO:0042493| response to drug HTR2B;ABCC1;ADRA1A;HTR2A;HTR1B;HTR2C 41831:[DB00399 DB00911] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00911|Tinidazole CYP3A4;ABCB11 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB11;ABCC1 41832:[DB00399 DB09129] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09129|Chromic chloride INSR common genes common pathways 41833:[DB00399 DB06796] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06796|Mangafodipir SOD2;A2M;ALB;SLC11A2 common genes common pathways 41834:[DB00399 DB06472] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06472|Fradafiban ITGA2B;ITGB3 common genes common pathways GO:0016032| viral reproduction FDPS;ITGB3 41835:[DB00399 DB00906] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00906|Tiagabine SLC6A1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug ABCC1;UGT1A1 GO:0008202| steroid metabolic process FDPS;CYP3A4;UGT1A1 GO:0006810| transport ABCC1;SLC6A1 GO:0055085| transmembrane transport ABCC1;SLC6A1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41836:[DB00399 DB08811] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08811|Tofisopam PDE4A;PDE10A;PDE3A;PDE2A;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;PDE3A GO:0006629| lipid metabolic process PDE3A;FDPS;CYP3A4 41837:[DB00399 DB01092] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01092|Ouabain ATP1A1;ATP1A2;ATP1A3;CYP1A1;SLCO1A2;SLC22A8;SLCO4C1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport SLCO1A2;ABCC1;SLCO1B1;SLC22A8;SLCO1C1;SLCO4C1;SLCO1B3 GO:0008202| steroid metabolic process FDPS;CYP1A1 GO:0042493| response to drug ATP1A1;CYP1A1;ATP1A3;ABCC1 41838:[DB00399 DB00942] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00942|Cycrimine CHRM1 common genes common pathways 41839:[DB00399 DB08860] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08860|Pitavastatin HMGCR;UGT2B7;UGT1A3;CYP2C9;CYP2C8;ALB;ORM1;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A1;ABCG2;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0016032| viral reproduction SLC10A1;FDPS GO:0006629| lipid metabolic process CYP2C9;FDPS;HMGCR;UGT2B7 GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0045540| regulation of cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0055085| transmembrane transport SLCO1B1;ABCB11;SLCO2B1;ABCG2;ABCC1;SLCO1B3;SLC10A1;ABCC2;ABCB1 GO:0008299| isoprenoid biosynthetic process GGPS1;FDPS;HMGCR GO:0006810| transport ABCG2;ABCC1;ABCB11;ABCC2;ABCB1;SLC10A1 GO:0008202| steroid metabolic process UGT2B7;HMGCR;CYP2C8;FDPS;CYP2C9 GO:0006694| steroid biosynthetic process FDPS;HMGCR GO:0042493| response to drug ABCB1;ABCC2;ABCC1;ABCG2 GO:0099133| ABCC2;ABCC1 GO:0006695| cholesterol biosynthetic process FDPS;GGPS1;HMGCR GO:0008203| cholesterol metabolic process HMGCR;FDPS 41840:[DB00399 DB12010] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12010|Fostamatinib SYK;ADORA3;VMAT2;FAAH;SLC29A1;UGT1A1;PDE5A;ALOX5;CTSS;CTSL;ABL1;RPS6KA6;TYK2;COQ8A;JAK1;MET;NIM1K;STK26;PRKACA;STK24;STK3;TEC;STK33;STK35;STK36;STK38;STK38L;STK39;TAOK1;TAOK2;TAOK3;TBK1;TEK;TESK1;TGFBR1;TGFBR2;TIE1;TLK1;TLK2;TNIK;TNK1;TNK2;TNNI3K;TSSK1B;TTK;TXK;TYRO3;ULK1;ULK2;ULK3;WEE1;YES1;MAP3K19;ZAP70;AAK1;ABL2;ACVR1;ACVR1B;COQ8B;ALK;ANKK1;AURKA;AURKB;AURKC;AXL;BLK;BMP2K;BMPR1B;BMPR2;BMX;BRAF;BTK;CAMK1;CAMK1D;CAMK1G;CAMK2A;CAMK2B;CAMK2D;CAMK2G;CAMKK1;CAMKK2;CASK;CSN3;CDK1;CDC42BPG;CDK4;CDKL1;CDKL2;CHEK1;CHEK2;CIT;CLK1;CLK2;CLK3;CLK4;CSF1R;CSK;CSNK1A1;CSNK2A1;CSNK2A2;DAPK1;DAPK2;DAPK3;DCLK1;DCLK2;DCLK3;DDR1;DDR2;DYRK1A;DYRK1B;EGFR;EIF2AK1;EIF2AK2;EIF2AK4;EPHA1;EPHA2;EPHA3;EPHA4;EPHA5;EPHA6;EPHA7;EPHA8;EPHB1;EPHB2;EPHB4;EPHB6;ERBB2;ERBB4;ERN1;FER;FES;FGFR1;FGFR2;FGFR3;FGR;FLT1;FLT3;FLT4;MTOR;FRK;FYN;GAK;GSK3A;GSK3B;HCK;HIPK2;HIPK3;ICK;IKBKB;IKBKE;INSR;INSRR;IRAK1;IRAK3;IRAK4;ITK;JAK2;JAK3;KDR;SIK3;KIT;LATS1;LCK;LIMK1;LIMK2;LRRK2;LTK;LYN;MAP2K2;MAP2K3;MAP2K5;MAP2K6;MAP3K1;MAP3K10;MAP3K11;MAP3K12;MAP3K13;MAP3K15;MAP3K2;MAP3K3;MAP3K4;MAP3K6;MAP3K9;MAP4K1;MAP4K2;MAP4K3;MAP4K4;MAP4K5;MAPK10;MAPK13;MAPK14;MAPK15;MAPK4;MAPK7;MAPK9;MAPKAPK5;MARK1;MARK2;MARK3;MARK4;CLASP1;MAST1;MATK;MELK;MERTK;MINK1;MKNK1;MKNK2;MST1R;MUSK;MYLK;MYLK2;MYLK3;MYLK4;MYO3A;NEK1;NEK11;NEK2;NEK3;NEK4;NEK5;NEK9;NTRK1;NTRK2;NTRK3;NUAK1;NUAK2;OXSR1;PAK1;PAK2;PAK3;PAK4;PAK6;PAK5;CDK16;CDK17;PDGFRA;PDGFRB;PDPK1;CDK15;PHKG1;PI4KB;PIK3C2B;PIK3C2G;PIK3CD;PIK3CG;PIM1;PIM3;PIP4K2B;PIP4K2C;PKMYT1;PKN1;PKN2;PLK1;PLK2;PLK3;PLK4;PRKAA1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;PRKACB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKD1;PRKG2;PRPF4B;PTK2;PTK2B;PTK6;RAF1;RET;RIOK1;RIOK2;RIOK3;RIPK1;RIPK2;RIPK4;ROCK2;ROS1;RPS6KA1;RPS6KA3;SBK1;SBK3;SGK3;SIK1;SIK2;SLK;SNRK;SRC;SRMS;STK10;STK16;STK17A;STK17B;STK32A;CYP3A4;UGT1A9;ABCG2;ABCB5 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB5 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB5 GO:0006629| lipid metabolic process CYP3A4;PRKAB2;PRKAA2;PRKAA1;PRKAG2;FDPS;PRKAB1;PRKAG1;PRKAG3 GO:0016126| sterol biosynthetic process FDPS;PRKAG2;PRKAA1;PRKAA2 GO:0016032| viral reproduction LYN;EPHA2;FYN;FDPS;IRAK1;PAK2;EIF2AK4;TBK1;SYK;TYRO3;PDGFRA;DYRK1A;EIF2AK2;RIPK1;HCK;SRC;LCK;KDR;AXL GO:0006810| transport ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;PRKAA1;PRKAA2;FDPS;UGT1A1 GO:0055085| transmembrane transport ABCG2;ABCC1;ABCB5;CSN3 GO:0006695| cholesterol biosynthetic process PRKAA1;GGPS1;PRKAA2;FDPS GO:0008203| cholesterol metabolic process PRKAA2;PRKAA1;FDPS GO:0060326| cell chemotaxis EPHB1;PDGFRB;PRKCQ;EPHA2;KIT;PRKCD;ABCC1;PDGFRA GO:0006694| steroid biosynthetic process FDPS;PRKAA2;PRKAA1 GO:0042493| response to drug PTK2B;RET;SRC;ABCC1;UGT1A1;ABCG2;MAP2K6;LCK;TGFBR2;CDK4;LYN;NTRK1;FYN;CDK1 GO:0006691| leukotriene metabolic process ALOX5;ABCC1 41841:[DB00399 DB14533] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14533|Zinc chloride BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0008202| steroid metabolic process FDPS;APOA1;APOBR;APOE;APOL1 GO:0006810| transport ABCC1;TTR GO:0055085| transmembrane transport ABCC1;APOA1 GO:0008203| cholesterol metabolic process APOA1;PON1;APOE;APOBR;APOL1;APP;APOA4;APOA2;FDPS GO:0006695| cholesterol biosynthetic process FDPS;APOA4;GGPS1;APOA1 GO:0042493| response to drug MDM2;MGMT;APOA2;HDAC4;ABCC1;APOA1;NME1;TP53;HDAC1;TP73;SOD1 GO:0060326| cell chemotaxis ABCC1;C5 GO:0006629| lipid metabolic process APOA1;PON1;C3;APOBR;APOE;APOL1;CLU;FDPS GO:0016032| viral reproduction TP73;TP53;HDAC1;SIVA1;IDE;FDPS;APOA2;CFH;MDM2 41842:[DB00399 DB00690] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00690|Flurazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP2E1;CYP2A6;CYP3A4;ABCB1;SLC22A2 common genes common pathways GO:0042493| response to drug GABRG3;ABCB1;ABCC1;CYP2E1 GO:0055085| transmembrane transport ABCB1;ABCC1;SLC22A2 GO:0008202| steroid metabolic process FDPS;CYP2A6;CYP3A4;CYP2E1 GO:0006810| transport GABRD;GABRR2;ABCC1;GABRA6;GABRR1;GABRA4;GABRB1;GABRB2;GABRA5;GABRA3;ABCB1;GABRG2;GABRB3;GABRA1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;SLC22A2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41843:[DB00399 DB04846] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04846|Celiprolol ADRB1;ADRB2;ADRB3;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process CYP2D6;FDPS 41844:[DB00399 DB01698] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01698|Rutin AKR1C3;CBR1;CYP2C8;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;FDPS;AKR1C3 41845:[DB00399 DB00896] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00896|Rimexolone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41846:[DB00399 DB00967] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00967|Desloratadine HRH1;CYP2C19;CYP1A2;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1;CYP1A2 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP2C19 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41847:[DB00399 DB06789] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06789|Hydroxyprogesterone caproate PGR;CYP3A4;CYP3A5;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP2C19;FDPS;CYP3A4 41848:[DB00399 DB11827] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11827|Ertugliflozin SLC5A2;UGT1A9;UGT2B7;UGT1A1;UGT1A4;ALB;ABCB1;ABCG2 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006629| lipid metabolic process UGT2B7;FDPS GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB1;SLC5A2 GO:0008202| steroid metabolic process UGT1A1;UGT2B7;FDPS GO:0006810| transport ABCC1;ABCG2;ABCB1;SLC5A2 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;ABCC1 41849:[DB00399 DB00584] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00584|Enalapril ACE;CYP3A4;ABCB1;SLC15A1;SLC22A6;SLC22A8;SLC22A7;SLCO1A2 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1;SLC15A1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport SLC15A1;ABCB1;SLC22A6;SLC22A7;SLC22A8;ABCC1;SLCO1A2 GO:0042493| response to drug ABCB1;ABCC1 41850:[DB00399 DB00485] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00485|Dicloxacillin CYP3A4;SLC15A1;SLC15A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport SLC15A2;ABCC1;SLC15A1 GO:0055085| transmembrane transport SLC15A2;ABCC1;SLC15A1 41851:[DB00399 DB12070] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12070|Letermovir UGT1A1;UGT1A3;CYP2D6;CYP2C8;CYP2C19;CYP2C9;CYP2B6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;SLCO1B1;SLCO1B3;ABCB1;ABCG2;ABCB11;SLC22A8;ABCC2 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2B6;CYP2C9;FDPS;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C8;UGT1A1 GO:0006810| transport ABCC2;ABCB1;ABCG2;ABCC1;ABCB11 GO:0055085| transmembrane transport SLC22A8;ABCB11;SLCO1B1;ABCC1;ABCG2;SLCO1B3;ABCB1;ABCC2 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC2;ABCB1;UGT1A1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;FDPS 41852:[DB00399 DB08934] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08934|Sofosbuvir CTSA;HINT1;CMPK1;NME1;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCB1;NME1;ABCG2;ABCC1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 41853:[DB00399 DB00520] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00520|Caspofungin CYP3A4;SLC22A1;ABCB1;SLC22A6;SLCO1B1;SLCO1B3 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;SLC22A1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport SLCO1B1;SLC22A6;ABCC1;SLCO1B3;ABCB1;SLC22A1 GO:0042493| response to drug ABCB1;ABCC1 41854:[DB00399 DB05708] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05708|GTS-21 CHRNA7;CYP1A2;CYP2E1 common genes common pathways GO:0042493| response to drug ABCC1;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2E1 GO:0006629| lipid metabolic process FDPS;CYP1A2 41855:[DB00399 DB00383] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00383|Oxyphencyclimine CHRM3;CHRM1;CHRM2 common genes common pathways 41856:[DB00399 DB00616] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00616|Candoxatril MME;ACE common genes common pathways 41857:[DB00399 DB00180] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00180|Flunisolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41858:[DB00399 DB08960] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08960|Hexamethonium CHRNA2 common genes common pathways 41859:[DB00399 DB13136] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13136|Fluindione CYP2C9;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;FDPS 41860:[DB00399 DB06716] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06716|Fospropofol GABRB2;GABRB3;ALPL;ALB common genes common pathways GO:0006810| transport GABRB2;ABCC1;GABRB3 41861:[DB00399 DB11855] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11855|Revefenacin CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ALB;SLCO1B1;SLCO1B3;ABCB1;ABCG2 common genes common pathways GO:0042493| response to drug ABCC1;ABCG2;ABCB1 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLCO1B1;ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 41862:[DB00399 DB00641] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00641|Simvastatin HMGCR;ITGB2;ITGAL;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0042493| response to drug ABCC1;UGT1A1;ABCC2;ABCB1 GO:0099133| ABCC1;ABCC2 GO:0006694| steroid biosynthetic process FDPS;HMGCR GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;HMGCR GO:0008203| cholesterol metabolic process HMGCR;FDPS GO:0045540| regulation of cholesterol biosynthetic process HMGCR;GGPS1;FDPS GO:0055085| transmembrane transport SLCO1B1;ABCB11;ABCC1;SLCO1A2;ABCB1;ABCC2 GO:0008299| isoprenoid biosynthetic process FDPS;GGPS1;HMGCR GO:0006810| transport ABCC2;ABCB1;ABCC1;ABCB11 GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP2B6;CYP2D6;CYP3A4;CYP3A7;UGT2B7;CYP3A5;HMGCR;UGT1A1;CYP2C19;CYP2C8 GO:0006629| lipid metabolic process HMGCR;UGT2B7;CYP3A4;CYP2D6;CYP2C9;FDPS GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 41863:[DB00399 DB12515] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12515|9-aminocamptothecin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41864:[DB00399 DB01497] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01497|Etorphine OPRM1;OPRD1;OPRK1;OPRL1;TRIM13;POMC common genes common pathways 41865:[DB00399 DB00264] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00264|Metoprolol ADRB1;ADRB2;CYP2D6;CYP2C19;SLC22A2;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A2;ABCB1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP2C19 GO:0006810| transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0006855| drug transmembrane transport SLC22A2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 41866:[DB00399 DB00523] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00523|Alitretinoin RARA;RXRA;RARB;RXRB;RARG;RXRG;IGFBP3;PSG5;CYP26C1;CRABP2;CRABP1;ABCB1 common genes common pathways GO:0008203| cholesterol metabolic process RXRA;FDPS GO:0042493| response to drug ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0016032| viral reproduction FDPS;RXRA GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 41867:[DB00399 DB00259] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00259|Sulfanilamide CYP2C19;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0042493| response to drug ABCC1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;CYP2C19;CYP2D6;FDPS;CYP3A4 41868:[DB00399 DB00683] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00683|Midazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRB1;GABRB3;GABRB2;GABRA6;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP4B1;UGT1A4;CYP2E1;ABCB1;ABCB11 common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1;GABRG3;ABCB1 GO:0055085| transmembrane transport ABCB11;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2E1;CYP3A7;CYP3A5;FDPS;CYP2B6;CYP3A4 GO:0006810| transport ABCB11;GABRB2;GABRA5;GABRA3;GABRA4;GABRA6;GABRR1;GABRB1;GABRD;ABCC1;GABRR2;GABRB3;GABRA1;GABRG2;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 41869:[DB00399 DB00306] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00306|Talbutal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0006810| transport GABRB2;GABRA3;GABRA5;GRIK2;GABRA6;GABRA4;GABRB1;GABRD;ABCC1;GABRB3;GABRA1;GABRG2 GO:0042493| response to drug ABCC1;GABRG3 41870:[DB00399 DB00288] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00288|Amcinonide NR3C1;ANXA1;CYP3A4 common genes common pathways GO:0042493| response to drug ANXA1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41871:[DB00399 DB00279] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00279|Liothyronine THRA;THRB;PCNA;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A10;ABCB1;SLC7A5 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0016032| viral reproduction SLC10A1;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport SLC10A1;SLCO1B3;ABCB1;SLCO4C1;SLCO1C1;SLC16A10;SLCO4A1;SLC22A8;SLCO1B1;ABCC1;SLCO1A2 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCB1;SLC7A5;TTR;SLC10A1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 41872:[DB00399 DB04975] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04975|Banoxantrone TOP2A;CYP1A1;CYP3A4;CYP2B6 common genes common pathways GO:0042493| response to drug ABCC1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;FDPS;CYP2B6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41873:[DB00399 DB00818] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00818|Propofol GABRB2;GABRB3;SCN4A;SCN2A;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP2B6;UGT1A8;UGT1A9;UGT1A1;FAAH;CYP2E1;CYP1B1;CYP1A1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;UGT1A6;ALB common genes common pathways GO:0055085| transmembrane transport SCN2A;ABCC1;SCN4A GO:0006810| transport GABRG2;GABRA1;GABRB3;GABRA6;GABRA4;GABRB1;GABRD;ABCC1;GABRB2;GABRA3;GABRA5 GO:0008202| steroid metabolic process CYP1B1;FDPS;CYP1A2;UGT1A8;CYP2C9;CYP2B6;CYP2C8;CYP2C19;UGT1A1;CYP2E1;CYP1A1 GO:0042493| response to drug ABCC1;UGT1A1;CYP2E1;CYP1A1;GABRG3;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;CYP1A2;FDPS 41874:[DB00399 DB00636] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00636|Clofibrate PPARA;CYP2E1;GSTA2;CYP3A4;CYP1A1;CYP2A6;CYP2B6;CYP4A11 common genes common pathways GO:0006629| lipid metabolic process FDPS;PPARA;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP2B6;CYP2A6;CYP3A4;CYP2E1;CYP1A1 GO:0042493| response to drug ABCC1;CYP1A1;CYP2E1 GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 41875:[DB00399 DB05115] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05115|NN344 INSR common genes common pathways 41876:[DB00399 DB06042] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06042|ZEN-012 TUBB;TUBB1;TUBB3;TUBB4A;TOP2A;TOP2B common genes common pathways 41877:[DB00399 DB14724] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14724|Emapalumab IFNG common genes common pathways 41878:[DB00399 DB05849] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05849|NCX 950 ADRB2 common genes common pathways 41879:[DB00399 DB04445] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04445|Mercuric iodide SULT2A1 common genes common pathways GO:0006629| lipid metabolic process SULT2A1;FDPS GO:0008202| steroid metabolic process FDPS;SULT2A1 41880:[DB00399 DB12923] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12923|Gallopamil CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41881:[DB00399 DB04934] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04934|Rifalazil rpoB;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41882:[DB00399 DB00751] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00751|Epinastine HRH1;HRH2;ADRA1A;ADRA2A;HTR2A;HTR7;CYP2B6;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP2B6;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ADRA1A;HTR2A;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0016032| viral reproduction HTR2A;FDPS 41883:[DB00399 DB00765] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00765|Metyrosine TH common genes common pathways GO:0042493| response to drug TH;ABCC1 41884:[DB00399 DB05824] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05824|CNS-5161 GRIN1 common genes common pathways 41885:[DB00399 DB01109] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01109|Heparin SERPINC1;F10;SELP;FGFR4;FGF4;FGF19;FGFR1;FGF1;FGFR2;FGF2;PF4;HGF;HPSE common genes common pathways GO:0060326| cell chemotaxis ABCC1;HGF 41886:[DB00399 DB00805] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00805|Minaprine MAOA;HTR2B;HTR2A;HTR2C;ACHE;SLC6A4;DRD1;DRD2;CHRM1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0016032| viral reproduction HTR2A;FDPS GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0055085| transmembrane transport SLC6A4;ABCC1 GO:0042493| response to drug HTR2B;ABCC1;DRD2;DRD1;HTR2A;SLC6A4;HTR2C 41887:[DB00399 DB06201] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06201|Rufinamide GRM5;SCN9A;CES1;CYP2E1;CYP3A4;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP2E1;CYP3A4;FDPS GO:0055085| transmembrane transport SCN9A;ABCC1 GO:0006695| cholesterol biosynthetic process FDPS;GGPS1;CES1 GO:0042493| response to drug ABCC1;CYP2E1 41888:[DB00399 DB00199] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00199|Erythromycin MLNR;KCNH2;ALB;CYP3A4;CYP3A7;CYP3A5;CYP2B6;CYP1A2;ABCB1;SLCO1B1;SLCO1B3;ABCB11 common genes common pathways GO:0006810| transport ABCB11;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2B6;CYP1A2;FDPS;CYP3A4;CYP3A5;CYP3A7 GO:0055085| transmembrane transport ABCB1;KCNH2;SLCO1B3;ABCC1;SLCO1B1;ABCB11 GO:0042493| response to drug ABCC1;CYP1A2;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2 41889:[DB00399 DB00374] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00374|Treprostinil PTGIR;PPARD;P2RY12;CYP2C9 common genes common pathways GO:0008203| cholesterol metabolic process PPARD;FDPS GO:0008202| steroid metabolic process CYP2C9;FDPS GO:0006629| lipid metabolic process FDPS;CYP2C9;PPARD 41890:[DB00399 DB04880] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04880|Enoximone PDE3A common genes common pathways GO:0006629| lipid metabolic process PDE3A;FDPS GO:0042493| response to drug ABCC1;PDE3A 41891:[DB00399 DB00947] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00947|Fulvestrant ESR1;CYP3A4;UGT1A1 common genes common pathways GO:0042493| response to drug ABCC1;UGT1A1 GO:0008202| steroid metabolic process UGT1A1;FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41892:[DB00399 DB08899] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08899|Enzalutamide AR;CYP2C8;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6;CYP3A5;ALB;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP2C9;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2B6;FDPS;CYP3A4;CYP3A5;CYP2C19;CYP2C8 GO:0006810| transport ABCB1;ABCC1;AR GO:0042493| response to drug ABCB1;ABCC1 41893:[DB00399 DB01134] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01134|Desoxycorticosterone pivalate NR3C2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41894:[DB00399 DB00253] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00253|Medrysone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41895:[DB00399 DB01323] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01323|St. John's Wort CYP3A4;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP2D6;CYP3A4 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 41896:[DB00399 DB06781] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06781|Difluprednate NR3C1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41897:[DB00399 DB01892] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01892|Hyperforin PTGS1;NR1I2;ALOX5;ABCC2;SLCO1B1 common genes common pathways GO:0042908| xenobiotic transport NR1I2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCC2 GO:0006629| lipid metabolic process PTGS1;FDPS GO:0006810| transport ABCC1;ABCC2 GO:0008202| steroid metabolic process FDPS;NR1I2 GO:0055085| transmembrane transport ABCC2;SLCO1B1;ABCC1 GO:0006691| leukotriene metabolic process ALOX5;ABCC1 GO:0042493| response to drug ABCC1;ABCC2 GO:0099133| ABCC1;ABCC2 41898:[DB00399 DB06804] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06804|Nonoxynol-9 PTGS2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;FDPS GO:0042493| response to drug PTGS2;ABCC1 41899:[DB00399 DB00969] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00969|Alosetron HTR3A;CYP2C9;CYP3A4;CYP1A2;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process CYP2E1;FDPS;CYP1A2;CYP2C9;CYP3A4 GO:0042493| response to drug CYP1A2;CYP2E1;ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP3A4 41900:[DB00399 DB12131] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12131|Vinpocetine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41901:[DB00399 DB00826] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00826|Natamycin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41902:[DB00399 DB04820] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04820|Nialamide MAOB;MAOA;COMT common genes common pathways GO:0042493| response to drug COMT;ABCC1;MAOB 41903:[DB00399 DB06754] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06754|Danaparoid SERPINC1 common genes common pathways 41904:[DB00399 DB13346] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13346|Bufexamac PTGS1;PTGS2;HDAC6;HDAC10 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process PTGS1;PTGS2;FDPS 41905:[DB00399 DB11742] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11742|Ebastine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41906:[DB00399 DB04920] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04920|Clevidipine CACNA1F;CACNA1S;CACNA1D;CACNA1C;CYP2C9;CYP2D6;CYP2E1;CYP2C19;CYP3A4;BCHE common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9;CYP2C19;CYP2E1 GO:0055085| transmembrane transport CACNA1D;CACNA1C;CACNA1S;ABCC1;CACNA1F GO:0042493| response to drug BCHE;ABCC1;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS 41907:[DB00399 DB06742] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06742|Ambroxol CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41908:[DB00399 DB03546] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03546|N-({4-[(1R)-4-[(2R,4S,5S)-2,4-diamino-6-oxohexahydropyrimidin-5-yl]-1-(2,2,2-trifluoro-1,1-dihydroxyethyl)butyl]phenyl}carbonyl)-L-glutamic acid GART common genes common pathways 41909:[DB00399 DB06218] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06218|Lacosamide SCN9A;SCN3A;SCN10A;CYP2C19;CYP2C9;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0055085| transmembrane transport ABCC1;SCN10A;SCN3A;SCN9A GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C9;CYP2C19 41910:[DB00399 DB01006] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01006|Letrozole CYP19A1;CYP19A1;CYP3A4;CYP2A6 common genes common pathways GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0008202| steroid metabolic process FDPS;CYP2A6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41911:[DB00399 DB13931] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13931|Netarsudil ROCK1;ROCK2 common genes common pathways 41912:[DB00399 DB07879] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07879|N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide HDAC4 common genes common pathways GO:0042493| response to drug ABCC1;HDAC4 41913:[DB00399 DB00257] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00257|Clotrimazole KCNN4;NR1I2;NR1I3;CYP2C8;CYP3A4;CYP2B6;CYP11A1;CYP2D6;CYP11B1;CYP19A1;CYP2A6;CYP2C9;CYP2E1;CYP3A7;ABCC3;ABCB1;ABCC2;ABCB11 common genes common pathways GO:0006629| lipid metabolic process CYP11B1;CYP2D6;CYP2C9;FDPS;CYP11A1;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC3;NR1I2;ABCC1 GO:0045332| phospholipid translocation KCNN4;ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC3;ABCC1 GO:0008203| cholesterol metabolic process FDPS;CYP11A1 GO:0006694| steroid biosynthetic process FDPS;CYP11A1;CYP19A1;CYP11B1 GO:0042493| response to drug ABCC2;ABCB1;ABCC1;CYP2E1 GO:0099133| ABCC1;ABCC3;ABCC2 GO:0006810| transport ABCC3;ABCC2;ABCB1;ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP2D6;CYP2B6;NR1I2;CYP2C9;FDPS;CYP11A1;CYP2C8;CYP11B1;CYP3A7;CYP2E1 GO:0055085| transmembrane transport ABCC2;ABCB1;ABCC3;ABCC1;ABCB11 41914:[DB00399 DB08865] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08865|Crizotinib ALK;MET;CYP3A4;CYP3A5;CYP2B6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;FDPS;CYP3A5;CYP3A7 GO:0042493| response to drug ABCB1;ABCC1 41915:[DB00399 DB00602] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00602|Ivermectin GLRA3;GABRB3;CYP3A4;ABCB1;ABCC1;ABCC2;ABCG2;SLCO1B1;SLCO1B3 common genes ABCC1 common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC1;ABCG2;GABRB3;ABCB1;ABCC2 GO:0055085| transmembrane transport ABCB1;ABCC2;SLCO1B3;ABCC1;ABCG2;SLCO1B1 GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug ABCC1;ABCG2;ABCC2;ABCB1 GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1;ABCG2 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41916:[DB00399 DB00155] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00155|L-Citrulline ASS1;DDAH2;ASS;DDAH1;OTC;NOS1;NOS2;NOS3;PADI6;PADI1;PADI3;PADI2;PADI4;SLC22A6 common genes common pathways GO:0042493| response to drug OTC;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A6 41917:[DB00399 DB08813] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08813|Nadroparin SERPINC1;SELP;FOS;MYC common genes common pathways GO:0042493| response to drug MYC;FOS;ABCC1 41918:[DB00399 DB09082] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09082|Vilanterol ADRB2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41919:[DB00399 DB00055] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00055|Drotrecogin alfa F8;F5;SERPINE1;THBD;PROS1;CP;F2;PF4;SERPINA5;SERPINB6;GGCX;PROCR common genes common pathways 41920:[DB00399 DB01359] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01359|Penbutolol ADRB1;ADRB2;HTR1A;HTR1B;CYP2D6;ORM1 common genes common pathways GO:0042493| response to drug HTR1B;ABCC1 GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006629| lipid metabolic process CYP2D6;FDPS 41921:[DB00399 DB00281] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00281|Lidocaine SCN10A;SCN9A;SCN5A;EGFR;SCN4A;ORM1;ORM2;CYP3A4;CYP2D6;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C18;CYP2A6;CYP2B6;SLC22A5;ABCB1 common genes common pathways GO:0055085| transmembrane transport SCN5A;ABCC1;SCN10A;SCN4A;SCN9A;SLC22A5;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP2A6;CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1 GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 41922:[DB00399 DB01110] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01110|Miconazole NOS3;NOS2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;KCNH2;KCNH6;KCNH7;NR1I2;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP11B1;CYP51A1;CYP19A1;ABCB1 common genes common pathways GO:0016126| sterol biosynthetic process FDPS;CYP51A1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP2C9;CYP3A4;CYP11B1;CYP51A1 GO:0045332| phospholipid translocation ABCC1;KCNN4;ABCB1 GO:0042908| xenobiotic transport ABCB1;NR1I2;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0008203| cholesterol metabolic process FDPS;CYP51A1 GO:0006695| cholesterol biosynthetic process CYP51A1;FDPS;GGPS1 GO:0006694| steroid biosynthetic process FDPS;CYP19A1;CYP51A1;CYP11B1 GO:0042493| response to drug ABCB1;CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP51A1;CYP11B1;CYP2E1;CYP2A6;CYP3A4;CYP2B6;NR1I2;CYP2C9;CYP2D6;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport KCNH7;KCNMA1;ABCC1;KCNH6;ABCB1;KCNH2 GO:0045540| regulation of cholesterol biosynthetic process FDPS;GGPS1;CYP51A1 41923:[DB00399 DB04884] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04884|Dapoxetine HTR1A;HTR1B;HTR2C;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 GO:0042493| response to drug HTR2C;HTR1B;ABCC1 41924:[DB00399 DB13981] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13981|Nomegestrol acetate CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41925:[DB00399 DB09017] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09017|Brotizolam CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41926:[DB00399 DB09121] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09121|Aurothioglucose ADCY1;ADCY2;ADCY5 common genes common pathways GO:0042493| response to drug ABCC1;ADCY1 41927:[DB00399 DB03010] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03010|Patupilone TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41928:[DB00399 DB00323] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00323|Tolcapone COMT;CYP2C9 common genes common pathways GO:0042493| response to drug COMT;ABCC1 GO:0008202| steroid metabolic process CYP2C9;FDPS GO:0006629| lipid metabolic process CYP2C9;FDPS 41929:[DB00399 DB00924] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00924|Cyclobenzaprine HTR2A;CYP1A2;CYP3A4;CYP2D6;UGT1A1 common genes common pathways GO:0042493| response to drug HTR2A;UGT1A1;ABCC1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP1A2;FDPS;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6 GO:0016032| viral reproduction FDPS;HTR2A 41930:[DB00399 DB01591] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01591|Solifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41931:[DB00399 DB13158] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13158|Clobetasone NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 41932:[DB00399 DB08893] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08893|Mirabegron ADRB3;CYP3A4;CYP2D6;BCHE;ALB;ORM1;ABCB1;SLCO1A2 common genes common pathways GO:0042493| response to drug ABCC1;BCHE;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0055085| transmembrane transport ABCC1;SLCO1A2;ABCB1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 41933:[DB00399 DB05416] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05416|Cardarine PPARD;PPARA common genes common pathways GO:0008203| cholesterol metabolic process PPARD;FDPS GO:0006629| lipid metabolic process FDPS;PPARA;PPARD 41934:[DB00399 DB06433] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06433|Tezacitabine RRM1;TYMP common genes common pathways 41935:[DB00399 DB00548] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00548|Azelaic acid trxB;AKR1D1;SRD5A2;TYR;polA common genes common pathways GO:0008202| steroid metabolic process FDPS;SRD5A2;AKR1D1 GO:0042493| response to drug SRD5A2;ABCC1 GO:0006694| steroid biosynthetic process SRD5A2;FDPS GO:0006629| lipid metabolic process FDPS;AKR1D1;SRD5A2 41936:[DB00399 DB00406] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00406|Gentian violet cation SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A1 GO:0055085| transmembrane transport SLC22A1;ABCC1 41937:[DB00399 DB09401] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09401|Isosorbide BCL2;BCL2L1;MCL1 common genes common pathways GO:0055085| transmembrane transport ABCC1;BCL2 GO:0042493| response to drug ABCC1;BCL2 41938:[DB00399 DB05309] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05309|TP-508 FGF4 common genes common pathways 41939:[DB00399 DB05050] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05050|ADL5859 OPRD1 common genes common pathways 41940:[DB00399 DB07348] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07348|Brefeldin A CYTH2;ARF1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 41941:[DB00399 DB00929] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00929|Misoprostol PTGER3;PTGER2;PTGER4 common genes common pathways 41942:[DB00399 DB07246] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07246|(2R)-2-AMINO-3,3,3-TRIFLUORO-N-HYDROXY-2-{[(4-PHENOXYPHENYL)SULFONYL]METHYL}PROPANAMIDE MMP9 common genes common pathways 41943:[DB00399 DB13385] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13385|Dihydroergocryptine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41944:[DB00399 DB08810] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08810|Cinitapride HTR1A;HTR2A;HTR4 common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0042493| response to drug ABCC1;HTR2A 41945:[DB00399 DB01000] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01000|Cyclacillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCC1 GO:0006810| transport SLC15A1;ABCC1;SLC15A2 GO:0055085| transmembrane transport SLC15A1;ABCC1;SLC15A2;SLC22A5 41946:[DB00399 DB06154] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06154|Pentaerythritol tetranitrate HBA1;HBB;GUCY1A2;NOS3;ALDH2 common genes common pathways 41947:[DB00399 DB06268] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06268|Sitaxentan EDNRA;EDNRB;CYP2C9;CYP3A4;CYP2C19 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP3A4;CYP2C19 41948:[DB00399 DB09234] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09234|Darodipine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41949:[DB00399 DB08916] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08916|Afatinib EGFR;ERBB2;ERBB4;ABCB1;ABCG2 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042493| response to drug ABCB1;ABCC1;ABCG2 41950:[DB00399 DB08884] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08884|Gadoxetic acid SLCO1B1;SLCO1B3;ABCC3;ABCC2;ABCC4 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCC3;ABCC1 GO:0042908| xenobiotic transport ABCC3;ABCC1 GO:0042493| response to drug ABCC1;ABCC4;ABCC2 GO:0099133| ABCC1;ABCC2;ABCC3;ABCC4 GO:0055085| transmembrane transport ABCC2;SLCO1B3;ABCC4;ABCC3;ABCC1;SLCO1B1 GO:0006810| transport ABCC2;ABCC3;ABCC1 41951:[DB00399 DB05109] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05109|Trabectedin CYP3A4;CYP2C9;CYP2D6;CYP2E1;CYP2C19;PTGS1 common genes common pathways GO:0006629| lipid metabolic process PTGS1;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;FDPS;CYP3A4;CYP2E1;CYP2C19 GO:0042493| response to drug ABCC1;CYP2E1 41952:[DB00399 DB01437] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01437|Glutethimide GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11A1;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP11A1;FDPS GO:0006810| transport GABRA3;GABRA5;GABRB2;GABRB1;GABRA6;GABRA4;ABCC1;GABRD;GABRB3;GABRA1;GABRG2 GO:0006694| steroid biosynthetic process CYP11A1;FDPS GO:0042493| response to drug ABCC1;GABRG3 GO:0008203| cholesterol metabolic process FDPS;CYP11A1 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP11A1 41953:[DB00399 DB06204] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06204|Tapentadol OPRM1;SLC6A2;OPRK1;OPRD1;HTR3A;SLC6A4;UGT1A9;UGT2B7;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP2D6;CYP2C19;UGT2B7 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport ABCC1;SLC6A2;SLC6A4 GO:0042493| response to drug SLC6A2;ABCC1;SLC6A4 GO:0006629| lipid metabolic process UGT2B7;FDPS;CYP2D6;CYP2C9 41954:[DB00399 DB09028] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09028|Cytisine CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2 common genes common pathways GO:0006810| transport ABCC1;CHRNA6 41955:[DB00399 DB00744] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00744|Zileuton ALOX5;CYP2C9;CYP1A2;CYP3A4;PTGS1;UGT1A9;ALB common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2C9;FDPS;CYP1A2 GO:0006691| leukotriene metabolic process ABCC1;ALOX5 GO:0042493| response to drug CYP1A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS;CYP1A2;PTGS1 41956:[DB00399 DB00937] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00937|Diethylpropion SLC6A2;SLC6A3 common genes common pathways GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A3;ABCC1;SLC6A2 GO:0042493| response to drug SLC6A3;SLC6A2;ABCC1 41957:[DB00399 DB13191] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13191|Phosphocreatine GAMT;SLC6A8;CKM;CKMT1A;CKMT2;CKB common genes common pathways GO:0006810| transport ABCC1;SLC6A8 GO:0055085| transmembrane transport ABCC1;SLC6A8 41958:[DB00399 DB06186] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06186|Ipilimumab CTLA4 common genes common pathways 41959:[DB00399 DB00247] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00247|Methysergide HTR2B;HTR2C;HTR2A;HTR1A;HTR7;HTR1B;HTR1F;HTR1E;CYP3A4 common genes common pathways GO:0042493| response to drug HTR2A;ABCC1;HTR2B;HTR2C;HTR1B GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0016032| viral reproduction HTR2A;FDPS 41960:[DB00399 DB03515] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03515|Equilenin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41961:[DB00399 DB05260] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05260|Gallium nitrate RRM2;ATP6V1B2;BGLAP;IL1B;TF;TFRC;TFR2 common genes common pathways GO:0016032| viral reproduction TFRC;FDPS 41962:[DB00399 DB04977] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04977|Plitidepsin CYP3A4;CYP2A6;CYP2E1;CYP4A11 common genes common pathways GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 GO:0042493| response to drug CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2A6;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41963:[DB00399 DB01239] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01239|Chlorprothixene DRD2;DRD1;DRD3;HTR2A;HTR2B;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0016032| viral reproduction FDPS;HTR2A GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug HTR2C;ABCB1;DRD3;DRD2;DRD1;HTR2A;HTR2B;ABCC1 41964:[DB00399 DB00724] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00724|Imiquimod TLR7;TLR8;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 41965:[DB00399 DB06271] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06271|Sulodexide SERPIND1;SERPINC1 common genes common pathways 41966:[DB00399 DB00367] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00367|Levonorgestrel PGR;SRD5A1;ESR1;AR;SHBG;CYP3A4;CYP19A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;SRD5A1 GO:0006694| steroid biosynthetic process SRD5A1;CYP19A1;FDPS GO:0042493| response to drug ABCC1;SRD5A1 GO:0006810| transport AR;ABCC1 GO:0008202| steroid metabolic process SRD5A1;FDPS;CYP3A4 41967:[DB00399 DB00364] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00364|Sucralfate FGF2;EGF;FGA;FGB;FGG;ALB common genes common pathways 41968:[DB00399 DB13956] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13956|Estradiol valerate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0099133| ABCC1;ABCC10 GO:0042493| response to drug ABCB1;CYP1A2;UGT1A1;ABCC1;ABCG2;CYP1A1;BECN1 GO:0006694| steroid biosynthetic process HSD17B2;FDPS GO:0055085| transmembrane transport SLC22A3;SLCO1B3;ABCB1;SLCO1C1;SLC22A1;SLCO4A1;ABCC10;SLCO1B1;SLC22A8;SLCO2B1;SLC22A2;SLC22A11;SLCO1A2;ABCG2;ABCC1 GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C9;NR1I2;FDPS;CYP1A2;CYP1B1;CYP3A4;CYP3A5;CYP1A1;CYP3A7;CYP2C8;CYP2C19;UGT1A1 GO:0016032| viral reproduction FDPS;BECN1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2C9;HSD17B2;CYP3A4 GO:0006855| drug transmembrane transport SLC22A2;ABCC1;ABCG2;SLC22A3;SLC22A1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1;NR1I2 GO:0045332| phospholipid translocation ABCB1;ABCC1 41969:[DB00399 DB01193] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01193|Acebutolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP2D6 41970:[DB00399 DB01624] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01624|Zuclopenthixol DRD1;DRD5;DRD2;ADRA1A;ADRA2A;HTR2A;HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042493| response to drug ABCC1;ADRA1A;DRD2;HTR2A;DRD1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 41971:[DB00399 DB03552] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03552|3-Tyrosine TH common genes common pathways GO:0042493| response to drug TH;ABCC1 41972:[DB00399 DB05766] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05766|ACP-104 CHRM1;DRD2;DRD3 common genes common pathways GO:0042493| response to drug ABCC1;DRD2;DRD3 41973:[DB00399 DB08883] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08883|Perampanel GRIA1;CYP3A4;CYP3A5;CYP1A2;CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS;CYP1A2;CYP2B6 GO:0042493| response to drug CYP1A2;ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4 41974:[DB00399 DB00352] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00352|Tioguanine HPRT1;ABCC4 common genes common pathways GO:0099133| ABCC1;ABCC4 GO:0042493| response to drug ABCC4;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCC4 41975:[DB00399 DB00445] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00445|Epirubicin CHD1;TOP2A;UGT2B7;PLA2G4A;ABCC1 common genes ABCC1 common pathways GO:0006855| drug transmembrane transport ABCC1 GO:0042908| xenobiotic transport ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process PLA2G4A;FDPS;UGT2B7 GO:0055085| transmembrane transport ABCC1 GO:0006810| transport ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process UGT2B7;FDPS GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCC1 GO:0099133| ABCC1 GO:0060326| cell chemotaxis ABCC1 41976:[DB00399 DB06738] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06738|Ketobemidone OPRM1;OPRK1;OPRD1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;PTGS1;CYP2C9;CYP3A4;UGT1A9;CYP2B6;CYP2C19;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;PTGS1 GO:0042493| response to drug GRIN2A;ABCC1 GO:0006810| transport GRIN2A;GRIN2B;ABCC1;GRIN2C GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2B6;CYP2C9;CYP2C8;CYP2C19 41977:[DB00399 DB05223] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05223|Pracinostat HDAC1;HDAC2;HDAC3;HDAC6 common genes common pathways GO:0016032| viral reproduction FDPS;HDAC1 GO:0042493| response to drug HDAC1;HDAC2;ABCC1 41978:[DB00399 DB12698] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12698|Ibalizumab CD4;CCR5;CXCR4 common genes common pathways GO:0016032| viral reproduction CD4;CXCR4;CCR5;FDPS 41979:[DB00399 DB01597] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01597|Cilastatin DPEP1;SLC22A6;SLC22A8 common genes common pathways GO:0006691| leukotriene metabolic process DPEP1;ABCC1 GO:0055085| transmembrane transport SLC22A8;SLC22A6;ABCC1 41980:[DB00399 DB00031] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00031|Tenecteplase PLG;FGA;PLAUR;SERPINE1;SERPINB2;CLEC3B;KRT8;ANXA2;CALR;CANX;LRP1 common genes common pathways GO:0042493| response to drug CALR;ABCC1 GO:0006629| lipid metabolic process LRP1;FDPS GO:0016032| viral reproduction KRT8;FDPS 41981:[DB00399 DB00642] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00642|Pemetrexed TYMS;ATIC;DHFR;GART;DCK;SLC29A1;SLC22A8 common genes common pathways GO:0042493| response to drug TYMS;ABCC1 GO:0055085| transmembrane transport SLC22A8;ABCC1 41982:[DB00399 DB02187] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02187|Equilin HSD17B1;ESR1;CYP3A4 common genes common pathways GO:0006694| steroid biosynthetic process HSD17B1;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process HSD17B1;CYP3A4;FDPS 41983:[DB00399 DB01207] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01207|Ridogrel TBXA2R;TBXAS1 common genes common pathways GO:0042493| response to drug TBXA2R;ABCC1 GO:0006629| lipid metabolic process FDPS;TBXAS1 41984:[DB00399 DB00043] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00043|Omalizumab FCER1A;MS4A2 common genes common pathways 41985:[DB00399 DB01194] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01194|Brinzolamide CA2;CA1;CA4;CA5A;CA3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 41986:[DB00399 DB09343] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09343|Tipiracil TYMP;SLC22A2;SLC47A1;SLC22A2;SLC47A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;ABCC1;SLC47A1 GO:0055085| transmembrane transport SLC22A2;ABCC1;SLC47A1 41987:[DB00399 DB00240] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00240|Alclometasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 41988:[DB00399 DB00954] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00954|Dirithromycin CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 41989:[DB00399 DB00860] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00860|Prednisolone NR3C1;CYP3A4;SERPINA6;SLCO1A2;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;SLCO1A2;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 41990:[DB00399 DB06176] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06176|Romidepsin HDAC1;HDAC2;HDAC4;HDAC6;ABCC1;CYP3A4;CYP3A5;CYP1A1;CYP2B6;CYP2C19;ABCB1;SLCO1B3 common genes ABCC1 common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3;ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP1A1;CYP3A5;CYP3A4;FDPS;CYP2B6 GO:0006810| transport ABCB1;ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug HDAC1;CYP1A1;HDAC2;ABCC1;HDAC4;ABCB1 GO:0099133| ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0016032| viral reproduction FDPS;HDAC1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 41991:[DB00399 DB00846] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00846|Flurandrenolide NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 41992:[DB00399 DB06209] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06209|Prasugrel P2RY12;CES2;CYP3A4;CYP2B6;CYP2C9;CYP2C19;ALB common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP3A4;FDPS;CYP2B6;CYP2C9 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4 41993:[DB00399 DB01125] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01125|Anisindione GGCX common genes common pathways 41994:[DB00399 DB01606] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01606|Tazobactam bla;bla;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC22A8;SLC22A6 41995:[DB00399 DB00851] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00851|Dacarbazine POLA2;PGD;CYP1A1;CYP1A2;CYP2E1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP1A1;CYP2E1 GO:0042493| response to drug CYP1A2;CYP1A1;CYP2E1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP1A2 41996:[DB00399 DB00481] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00481|Raloxifene ESR1;ESR2;SERPINB9;TFF1;CYP2B6;CYP2C8;AOX1;CYP19A1;CYP3A4;UGT1A1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042493| response to drug ABCC1;UGT1A1 GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2B6;CYP2C8;UGT1A1 41997:[DB00399 DB01536] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01536|Androstenedione HSD17B1;HSD3B1;AKR1C3;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process HSD17B1;FDPS;CYP3A4 GO:0006694| steroid biosynthetic process FDPS;HSD3B1;HSD17B1 GO:0008202| steroid metabolic process CYP3A4;AKR1C3;FDPS 41998:[DB00399 DB12498] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12498|Mogamulizumab CXCR4 common genes common pathways GO:0016032| viral reproduction CXCR4;FDPS 41999:[DB00399 DB11967] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11967|Binimetinib IL6;TNF;IL1B;MAP3K1;MAP2K2;UGT1A1;CYP1A2;CYP2C19 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS;UGT1A1;CYP2C19 GO:0042493| response to drug CYP1A2;UGT1A1;ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS 42000:[DB00399 DB00629] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00629|Guanabenz ADRA2A;ADRA2B;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP1A2 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process FDPS;CYP1A2 42001:[DB00399 DB01632] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01632|5-O-phosphono-alpha-D-ribofuranosyl diphosphate APRT;trpD;HPRT1;pyrE;UCKL1 common genes common pathways GO:0016032| viral reproduction FDPS;UCKL1 42002:[DB00399 DB05812] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05812|Abiraterone CYP17A1;CYP3A4;SULT2A1;CYP2D6;CYP2C8;CYP1A2;CYP2C19;CYP2C9;ALB;ORM1;ABCC1 common genes ABCC1 common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4;SULT2A1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006855| drug transmembrane transport ABCC1 GO:0042908| xenobiotic transport ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006691| leukotriene metabolic process ABCC1 GO:0099133| ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0006694| steroid biosynthetic process CYP17A1;FDPS GO:0055085| transmembrane transport ABCC1 GO:0006810| transport ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP2C9;CYP2D6;CYP1A2;FDPS;CYP3A4;SULT2A1;CYP17A1;CYP2C8;CYP2C19 42003:[DB00399 DB01114] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01114|Chlorphenamine HRH1;SLC6A4;SLC6A2;SLC6A3;CYP3A7;CYP3A4;CYP2D6;CYP3A5;SLC22A2;SLC22A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A1 GO:0042493| response to drug SLC6A4;ABCC1;SLC6A2;SLC6A3 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;FDPS;CYP2D6;CYP3A4 GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC22A2;SLC6A3;ABCC1;SLC6A2;SLC6A4;SLC22A1 42004:[DB00399 DB08905] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08905|Formestane CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42005:[DB00399 DB00054] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00054|Abciximab ITGB3;ITGA2B;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;VTN common genes common pathways GO:0016032| viral reproduction FCGR2B;ITGB3;FDPS 42006:[DB00399 DB01277] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01277|Mecasermin IGF1R;IGFBP3;INSR;IGF2R common genes common pathways 42007:[DB00399 DB02746] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02746|Phthalic Acid nadC;ESR1;PGR;ESR2;PPARA;PPARD;PPARG;RXRA;RXRB;RXRG;SLCO2B1 common genes common pathways GO:0006629| lipid metabolic process FDPS;PPARA;PPARD;PPARG GO:0016032| viral reproduction RXRA;FDPS GO:0008203| cholesterol metabolic process FDPS;PPARD;RXRA GO:0042493| response to drug ABCC1;PPARG GO:0055085| transmembrane transport SLCO2B1;ABCC1 42008:[DB00399 DB00005] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00005|Etanercept TNF;TNFRSF1B;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;LTA;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0016032| viral reproduction FCGR2B;FDPS GO:0042493| response to drug LTA;ABCC1 42009:[DB00399 DB01180] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01180|Rescinnamine ACE common genes common pathways 42010:[DB00399 DB00216] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00216|Eletriptan HTR1D;HTR1B;HTR1F;HTR1A;HTR1E;HTR2B;HTR7;CYP3A4;CYP2D6;CYP2C9;CYP2C19;PTGS1;CYP2A6;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2A6;CYP2C9;CYP2D6;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;HTR1B;ABCC1;HTR2B GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process PTGS1;CYP2D6;CYP2C9;FDPS;CYP3A4 42011:[DB00399 DB00975] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00975|Dipyridamole PDE10A;ADA;PDE5A;PDE4A;RCAN1;ORM1;ABCC4;ABCC5;ABCB1;SLCO1B1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0099133| ABCC1;ABCC4;ABCC5 GO:0042493| response to drug ABCC1;ADA;ABCB1;ABCC4 GO:0055085| transmembrane transport ABCB1;ABCC5;ABCC4;SLCO1B3;ABCC1;SLCO2B1;ABCB11;SLCO1B1 GO:0006810| transport ABCC5;ABCB1;ABCC1;ABCB11 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 42012:[DB00399 DB00528] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00528|Lercanidipine CACNG1;CYP3A7;CYP3A4;CYP3A5;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP2D6;FDPS;CYP3A4 GO:0006810| transport CACNG1;ABCC1 42013:[DB00399 DB12537] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12537|Benzodiazepine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 42014:[DB00399 DB04886] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04886|Calanolide A CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42015:[DB00399 DB07615] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07615|Tranilast HPGDS;CYP3A4;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP2C9;FDPS;HPGDS;CYP3A4 42016:[DB00399 DB05075] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05075|TG-100801 FLT1;KDR;FLT4;CSK common genes common pathways GO:0016032| viral reproduction KDR;FDPS 42017:[DB00399 DB01100] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01100|Pimozide DRD2;DRD3;KCNH2;CALM1;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP1A2;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042493| response to drug ABCC1;DRD2;CYP2E1;DRD3;ABCB1;CYP1A2 GO:0055085| transmembrane transport KCNH2;ABCB1;CALM1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4;CYP3A5;CYP3A7;CYP2E1 42018:[DB00399 DB00067] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00067|Vasopressin AVPR2;AVPR1A;AVPR1B;ABCC2 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCC1 GO:0006810| transport ABCC1;ABCC2 GO:0055085| transmembrane transport ABCC2;ABCC1 GO:0099133| ABCC2;ABCC1 GO:0042493| response to drug ABCC2;ABCC1 42019:[DB00399 DB00983] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00983|Formoterol ADRB2;ADRB1;ADRB3;CYP2D6;CYP2C19;CYP2C9;CYP2A6 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2A6;FDPS;CYP2D6;CYP2C9 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP2C9 42020:[DB00399 DB02902] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02902|3'-Phosphate-Adenosine-5'-Phosphate Sulfate SULT1E1 common genes common pathways GO:0008202| steroid metabolic process SULT1E1;FDPS 42021:[DB00399 DB04599] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04599|Aniracetam HTR2A;DRD2;GRIA2;GRIA3 common genes common pathways GO:0016032| viral reproduction HTR2A;FDPS GO:0006810| transport ABCC1;GRIA3 GO:0042493| response to drug DRD2;HTR2A;ABCC1 42022:[DB00399 DB00935] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00935|Oxymetazoline ADRA1A;ADRA2A;ADRA2C;ADRA2B;ADRA1B;ADRA1D common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A 42023:[DB00399 DB01341] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01341|Dihydroquinidine barbiturate GABRA1 common genes common pathways GO:0006810| transport GABRA1;ABCC1 42024:[DB00399 DB00763] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00763|Methimazole TPO;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2C9;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2E1;CYP2A6;CYP3A4;CYP2D6;CYP2B6;CYP2C9;FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;ABCC1;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 42025:[DB00399 DB08868] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08868|Fingolimod S1PR5;HDAC1;CYP4F2;SPHK1;CYP2E1;CYP4F12 common genes common pathways GO:0016032| viral reproduction HDAC1;FDPS GO:0042493| response to drug ABCC1;HDAC1;CYP2E1 GO:0006691| leukotriene metabolic process ABCC1;CYP4F2 GO:0008202| steroid metabolic process FDPS;CYP2E1 42026:[DB00399 DB09274] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09274|Artesunate CYP2A6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2A6;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 42027:[DB00399 DB00575] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00575|Clonidine ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP3A5;SLC22A3;SLC22A5;SLC22A4;ABCB1 common genes common pathways GO:0042493| response to drug CYP1A2;ABCB1;ADRA1A;CYP1A1;ABCC1 GO:0055085| transmembrane transport ABCB1;SLC22A4;SLC22A3;ABCC1;SLC22A5 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP1A2;FDPS;CYP1A1;CYP3A5 GO:0006810| transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0006855| drug transmembrane transport SLC22A3;ABCB1;SLC22A5;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 42028:[DB00399 DB11919] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11919|6-O-benzylguanine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 42029:[DB00399 DB08907] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08907|Canagliflozin SLC5A2;SLC5A1;UGT1A9;UGT2B4;CYP3A4;ALB;ORM1;ABCB1;ABCC2 common genes common pathways GO:0042493| response to drug ABCB1;ABCC2;ABCC1 GO:0099133| ABCC2;ABCC1 GO:0006810| transport ABCC1;ABCB1;ABCC2;SLC5A2 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;ABCC2;ABCB1;SLC5A2;SLC5A1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC2;ABCB1;ABCC1 42030:[DB00399 DB12248] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12248|Tulobuterol ADRB2 common genes common pathways 42031:[DB00399 DB11575] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11575|Grazoprevir CYP3A4;ALB;ORM1;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport SLCO1B3;ABCB1;SLCO1B1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 42032:[DB00399 DB08881] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08881|Vemurafenib BRAF;CYP1A2;CYP2D6;CYP3A4;CYP2C9;CYP2C8;CYP2B6;ALB;ORM1;ABCC1;ABCG2 common genes ABCC1 common pathways GO:0060326| cell chemotaxis ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug CYP1A2;ABCG2;ABCC1 GO:0099133| ABCC1 GO:0055085| transmembrane transport ABCG2;ABCC1 GO:0006810| transport ABCC1;ABCG2 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;CYP2B6;CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 GO:0006855| drug transmembrane transport ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1 42033:[DB00399 DB11327] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11327|Dipyrithione NOS2;PTGS2 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process PTGS2;FDPS 42034:[DB00399 DB14542] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14542|Hydrocortisone phosphate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 GO:0006694| steroid biosynthetic process FDPS;CYP11B2;HSD3B1;CYP11B1 GO:0042493| response to drug ABCC1;ABCG2;HSD11B2;ANXA1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP11B2;CYP3A5;CYP3A7;CYP11B1;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0055085| transmembrane transport ABCC1;ABCG2;SLCO1A2;SLC22A8;ABCB1 42035:[DB00399 DB00541] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00541|Vincristine TUBB;TUBA4A;CYP3A5;CYP3A7;CYP3A4;ABCB1;ABCC3;SLC22A3;ABCC1;ABCC10;ABCC2;ABCB11;ABCG2;RALBP1;SLCO1B1;SLCO1B3 common genes ABCC1 common pathways GO:0099133| ABCC1;ABCC10;ABCC2;ABCC3 GO:0042493| response to drug ABCC2;ABCB1;ABCG2;ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A7;CYP3A5 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCC3;ABCB1;ABCC2;ABCB11;ABCG2;ABCC1 GO:0055085| transmembrane transport RALBP1;ABCC10;SLCO1B1;ABCB11;ABCC1;ABCG2;ABCC3;SLC22A3;SLCO1B3;ABCB1;ABCC2 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCC3;ABCB1 GO:0006855| drug transmembrane transport ABCC3;SLC22A3;ABCC2;ABCB1;RALBP1;ABCC1;ABCG2 42036:[DB00399 DB11574] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11574|Elbasvir CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 42037:[DB00399 DB00583] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00583|Levocarnitine SLC22A4;SLC22A5;CRAT;SLC25A29;SLC25A20;CROT;CPT2;CPT1A;XDH;CES1;MPO;SLC22A4;SLCO1B1;SLC22A5;SLC22A16;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process CROT;CPT1A;FDPS;CPT2;CRAT GO:0006855| drug transmembrane transport ABCC1;SLC22A5 GO:0006695| cholesterol biosynthetic process CES1;GGPS1;FDPS GO:0042493| response to drug ABCC1;CPT1A GO:0055085| transmembrane transport ABCC1;SLC25A29;SLCO1B1;SLC22A5;SLC22A8;SLC22A4;SLC22A16 42038:[DB00399 DB05212] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05212|HE3286 NFKB1;NFKB2;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 42039:[DB00399 DB11828] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11828|Neratinib EGFR;CYP3A4;FMO3;ALB;ORM1;ORM2;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 42040:[DB00399 DB05281] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05281|S-8184 TUBA4A;BCL2 common genes common pathways GO:0042493| response to drug ABCC1;BCL2 GO:0055085| transmembrane transport ABCC1;BCL2 42041:[DB00399 DB00158] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00158|Folic Acid FOLR2;FOLR3;FOLR1;CYP2E1;GGH;MTHFR;ALB;ABCC3;ABCC11;SLC22A6;ABCC4;ABCG2;SLC46A1;SLC25A32 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCC3 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCC3 GO:0055085| transmembrane transport ABCG2;ABCC1;SLC46A1;SLC22A6;ABCC11;ABCC4;ABCC3 GO:0008202| steroid metabolic process FDPS;CYP2E1 GO:0006810| transport ABCC1;ABCG2;ABCC3 GO:0042493| response to drug GGH;CYP2E1;ABCC1;ABCG2;MTHFR;ABCC4 GO:0099133| ABCC1;ABCC3;ABCC4;ABCC11 42042:[DB00399 DB04356] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04356|9-Deazaguanine HPRT1;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0042493| response to drug ABCC1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS 42043:[DB00399 DB00901] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00901|Bitolterol ADRB2 common genes common pathways 42044:[DB00399 DB01303] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01303|Oxtriphylline PDE3A;PDE4A;ADORA2A;ADORA1;HDAC2;CYP1A2;SLC22A7 common genes common pathways GO:0006629| lipid metabolic process PDE3A;FDPS;CYP1A2 GO:0008202| steroid metabolic process FDPS;CYP1A2 GO:0055085| transmembrane transport ABCC1;SLC22A7 GO:0042493| response to drug ADORA2A;ABCC1;HDAC2;PDE3A;CYP1A2 42045:[DB00399 DB08341] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08341|4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide PTK2B common genes common pathways GO:0042493| response to drug ABCC1;PTK2B 42046:[DB00399 DB00234] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00234|Reboxetine SLC6A2;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;SLC6A2 GO:0055085| transmembrane transport ABCC1;SLC6A2;ABCB1 GO:0006810| transport ABCB1;ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 42047:[DB00399 DB00535] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00535|Cefdinir MPO;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC15A1;SLC22A5;SLC15A2;SLC22A8;SLC22A6;ABCC1 GO:0006810| transport ABCC1;SLC15A2;SLC15A1 GO:0006855| drug transmembrane transport ABCC1;SLC22A5 42048:[DB00399 DB13456] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13456|Midecamycin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42049:[DB00399 DB11799] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11799|Bictegravir pol;pol;CYP3A4;UGT1A1;POU2F2;SLC47A1 common genes common pathways GO:0006855| drug transmembrane transport SLC47A1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;FDPS;CYP3A4 GO:0055085| transmembrane transport SLC47A1;ABCC1 GO:0042493| response to drug ABCC1;UGT1A1 42050:[DB00399 DB12329] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12329|Eravacycline rpsD;CYP3A4;MAOA common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42051:[DB00399 DB01365] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01365|Mephentermine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0042493| response to drug ABCC1;ADRA1A 42052:[DB00399 DB01011] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01011|Metyrapone CYP11B1;CYP11B2;CYP2A6;CYP3A4;CYP11B1;CYP2E1;ABCC3 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCC3 GO:0042908| xenobiotic transport ABCC3;ABCC1 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;ABCC3 GO:0008202| steroid metabolic process CYP11B2;CYP2E1;CYP11B1;CYP2A6;CYP3A4;FDPS GO:0006810| transport ABCC1;ABCC3 GO:0099133| ABCC1;ABCC3 GO:0042493| response to drug ABCC1;CYP2E1 GO:0006694| steroid biosynthetic process FDPS;CYP11B2;CYP11B1 42053:[DB00399 DB00219] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00219|Oxyphenonium CHRM1 common genes common pathways 42054:[DB00399 DB13928] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13928|Semaglutide GLP1R;DPP4;MME;LPL;AMY1A;ALB;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process LPL;FDPS GO:0055085| transmembrane transport ABCC1;SLCO1B1;SLCO1B3 GO:0042493| response to drug LPL;ABCC1 42055:[DB00399 DB13139] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13139|Levosalbutamol ADRB2;CYP3A4;CYP2D6;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport SLCO1B3;ABCC1;SLCO1B1 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 42056:[DB00399 DB01152] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01152|Candicidin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42057:[DB00399 DB00313] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00313|Valproic Acid HDAC9;ABAT;ACADSB;OGDH;ALDH5A1;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;HDAC2;PPARA;PPARD;PPARG;CYP2A6;CYP2B6;CYP2C9;CYP3A5;PTGS1;CYP1A2;CYP2C18;CYP2C19;CYP2C8;CYP3A4;UGT1A4;UGT1A8;UGT1A10;UGT1A6;UGT1A3;UGT2B7;UGT2B15;UGT1A9;UGT1A1;ALB;SLC22A5;SLC22A6;SLC22A8;SLC16A1;SLC22A7;SLCO2B1 common genes common pathways GO:0042493| response to drug CYP1A2;PPARG;ABAT;SCN11A;UGT1A1;ABCC1;HDAC2 GO:0008203| cholesterol metabolic process FDPS;PPARD GO:0055085| transmembrane transport SCN2A;SCN8A;SCN7A;SLC16A1;SCN11A;SLC22A6;SCN3A;SLCO2B1;SLC22A8;SLC22A5;SCN9A;SCN1A;SLC22A7;ABCC1;SCN10A;SCN4A;SCN5A GO:0008202| steroid metabolic process CYP3A4;CYP2A6;CYP2C9;CYP2B6;UGT1A8;FDPS;CYP1A2;CYP2C8;CYP2C19;UGT1A1;UGT2B15;CYP3A5;UGT2B7 GO:0006629| lipid metabolic process ACADSB;PTGS1;UGT2B7;CYP2C9;CYP1A2;SLC16A1;FDPS;PPARG;CYP3A4;PPARA;PPARD GO:0006855| drug transmembrane transport SLC22A5;ABCC1 42058:[DB00399 DB00354] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00354|Buclizine HRH1;CHRM1 common genes common pathways 42059:[DB00399 DB00476] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00476|Duloxetine SLC6A4;SLC6A2;SLC6A3;CYP1A2;CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2D6;CYP3A4 GO:0055085| transmembrane transport SLC6A4;ABCC1;SLC6A2;SLC6A3 GO:0008202| steroid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0006810| transport SLC6A2;ABCC1 GO:0042493| response to drug SLC6A2;ABCC1;SLC6A3;SLC6A4;CYP1A2 42060:[DB00399 DB11963] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11963|Dacomitinib EGFR;CYP2D6;CYP3A4;CYP2C9;UGT1A1;ALB;ABCB1;ABCG2;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP2C9;CYP3A4 GO:0055085| transmembrane transport ABCG2;ABCC1;ABCB1;SLC22A1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4;UGT1A1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0042493| response to drug ABCB1;UGT1A1;ABCC1;ABCG2 42061:[DB00399 DB14512] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14512|Mometasone furoate NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP2C8;FDPS;CYP3A4 42062:[DB00399 DB00185] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00185|Cevimeline CHRM3;CHRM1;CYP2D6;CYP3A4;FMO1 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS 42063:[DB00399 DB09123] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09123|Dienogest PGR;AR;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006810| transport AR;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 42064:[DB00399 DB09325] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09325|Sodium fluoride GPT;MT-CO1 common genes common pathways 42065:[DB00399 DB00115] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00115|Cyanocobalamin MTR;MUT;MTRR;MMAA;MMACHC;MTHFR;MMAB;MUT;MTR;TCN2;AMN;TCN1;TCN2;GIF;CUBN;MTR common genes common pathways GO:0015889| cobalamin transport CUBN;AMN;TCN2;TCN1;ABCC1;GIF GO:0006629| lipid metabolic process FDPS;CUBN GO:0008202| steroid metabolic process FDPS;CUBN GO:0009235| cobalamin metabolic process MMACHC;MMAA;MUT;MMAB;AMN;MTR;CUBN;GIF;ABCC1;MTRR;TCN1;TCN2 GO:0042493| response to drug ABCC1;MTHFR GO:0008203| cholesterol metabolic process FDPS;CUBN 42066:[DB00399 DB06626] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06626|Axitinib FLT1;KDR;FLT4;CYP3A4;CYP3A5;CYP1A2;CYP2C19;UGT1A1;ABCB1;SLCO1B1 common genes common pathways GO:0016032| viral reproduction FDPS;KDR GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;UGT1A1;ABCB1;CYP1A2 GO:0055085| transmembrane transport SLCO1B1;ABCC1;ABCB1 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP3A5;CYP3A4;CYP1A2;FDPS GO:0006810| transport ABCB1;ABCC1 42067:[DB00399 DB06454] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06454|Sarizotan HTR1A;DRD2;DRD3 common genes common pathways GO:0042493| response to drug ABCC1;DRD2;DRD3 42068:[DB00399 DB00677] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00677|Isoflurophate ACHE;BCHE;TF;BCHE;ALB common genes common pathways GO:0042493| response to drug BCHE;ABCC1 42069:[DB00399 DB00136] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00136|Calcitriol VDR;HOXA10;GC;CYP24A1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 42070:[DB00399 DB00776] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00776|Oxcarbazepine SCN5A;CYP2C19;CYP3A4;CYP3A5;UGT1A1;ALB;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5;CYP2C19;UGT1A1 GO:0055085| transmembrane transport ABCC1;SCN5A;ABCB1 GO:0042493| response to drug ABCB1;ABCC1;UGT1A1 42071:[DB00399 DB11323] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11323|Glycol salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCC1 GO:0006629| lipid metabolic process FDPS;PTGS1;PTGS2 42072:[DB00399 DB14544] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14544|Hydrocortisone valerate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;ABCG2;ABCC1;SLCO1A2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A7;CYP11B1;CYP3A5;CYP11B2;CYP2C8 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0042493| response to drug ABCB1;HSD11B2;ANXA1;ABCG2;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP11B2;HSD3B1;CYP11B1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP11B2;CYP11B1 42073:[DB00399 DB14481] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14481|Calcium phosphate dihydrate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0016032| viral reproduction SLC20A2;FDPS GO:0055085| transmembrane transport CACNA1F;CATSPER1;SLC34A3;RYR1;CACNA1I;CACNA1A;CACNA1G;CACNA1E;TRPV6;RYR2;CACNA1S;ABCC1;CALM1;CACNA1H;SLC20A1;SLC34A2;TRPV5;RYR3;CACNA1D;SLC8A1;CACNA1C;SLC20A2 GO:0006810| transport CACNA1I;CACNA1E;SLC20A2;SRI;CACNB4;SLC20A1;CACNB1;CACNB3;ABCC1 GO:0042493| response to drug SLC8A1;ABCC1;CALR;SLC34A1 42074:[DB00399 DB09308] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09308|Solithromycin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 42075:[DB00399 DB05266] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05266|Ibudilast PDE4A;PDE4B;PDE4C;PDE4D;PDE3A common genes common pathways GO:0042493| response to drug PDE3A;ABCC1 GO:0006629| lipid metabolic process FDPS;PDE3A 42076:[DB00399 DB01071] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01071|Mequitazine HRH1;CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 42077:[DB00399 DB01427] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01427|Amrinone PDE3A;PDE4B;TNF common genes common pathways GO:0042493| response to drug ABCC1;PDE3A GO:0006629| lipid metabolic process PDE3A;FDPS 42078:[DB00399 DB00349] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00349|Clobazam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C19;CYP2B6;CYP2C18;CYP2D6;SLC6A1;SLC6A11;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLC6A1;SLC6A11;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;CYP2D6;FDPS;CYP2C19 GO:0006810| transport GABRB2;GABRA5;GABRA3;GABRD;ABCC1;GABRA4;GABRA6;GABRB1;GABRB3;GABRA1;SLC6A1;ABCB1;GABRG2 GO:0042493| response to drug SLC6A11;ABCC1;ABCB1;GABRG3 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 42079:[DB00399 DB05229] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05229|Beraprost PTGIR;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;FDPS 42080:[DB00399 DB05488] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05488|Technetium Tc-99m ciprofloxacin gyrB;TOP2B;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 42081:[DB00399 DB01394] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01394|Colchicine TUBB1;TUBB;CYP3A4;CYP2B6;CYP2C8;CYP2E1;ABCB4;SLC22A3;ABCB1;ABCC1 common genes ABCC1 common pathways GO:0042908| xenobiotic transport ABCB4;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1;ABCB4 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport SLC22A3;ABCB1;ABCB4;ABCC1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process ABCB4;FDPS;CYP3A4 GO:0006810| transport ABCB4;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4;FDPS;CYP2B6 GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport SLC22A3;ABCB1;ABCB4;ABCC1 GO:0099133| ABCC1 GO:0042493| response to drug ABCC1;ABCB4;CYP2E1;ABCB1 GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 42082:[DB00399 DB14541] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14541|Hydrocortisone cypionate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0042493| response to drug ABCC1;ABCG2;ABCB1;HSD11B2;ANXA1 GO:0006694| steroid biosynthetic process CYP11B1;HSD3B1;CYP11B2;FDPS GO:0055085| transmembrane transport ABCB1;SLC22A8;ABCG2;ABCC1;SLCO1A2 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP11B1;CYP2C8;CYP11B2;FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP11B2;CYP11B1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 42083:[DB00399 DB01037] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01037|Selegiline MAOB;MAOA;CYP2B6;CYP3A4;CYP2A6;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1;CYP2E1;MAOB GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2E1;CYP2A6;CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2B6;CYP2C9 GO:0006810| transport ABCC1;ABCB1 42084:[DB00399 DB00927] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00927|Famotidine HRH2;CYP2C19;SLC22A2;SLC22A8 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A2;SLC22A8 GO:0008202| steroid metabolic process FDPS;CYP2C19 42085:[DB00399 DB09006] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09006|Clinofibrate PPARA;PPARG;PPARD common genes common pathways GO:0042493| response to drug PPARG;ABCC1 GO:0008203| cholesterol metabolic process PPARD;FDPS GO:0006629| lipid metabolic process PPARD;PPARA;PPARG;FDPS 42086:[DB00399 DB00363] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00363|Clozapine DRD2;HTR2A;DRD1;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;HRH4;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALY;GSTP1;CYP1A2;CYP2D6;CYP2C9;CYP3A4;CYP2C19;CYP2A6;CYP2C8;FMO3;UGT1A4;CYP2E1;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0042493| response to drug CYP2E1;HTR2A;DRD1;CYP1A1;ADRA1A;DRD2;ABCC1;CYP1A2;HTR2C;DRD3;HTR1B;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP1B1;CYP1A2;FDPS;CYP2C9;CYP2D6;CYP2C8;CYP2C19;CYP2E1;CYP1A1 GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 42087:[DB00399 DB09318] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09318|Synthetic Conjugated Estrogens, B ESR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 42088:[DB00399 DB00928] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00928|Azacitidine DNMT1;CDA common genes common pathways 42089:[DB00399 DB05029] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05029|Lancovutide PLA2G4A common genes common pathways GO:0006629| lipid metabolic process PLA2G4A;FDPS 42090:[DB00399 DB00564] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00564|Carbamazepine SCN5A;CHRNA4;CHRNB2;NR1I2;CYP3A4;CYP2C8;CYP1A2;CYP2C9;CYP2C19;CYP2B6;CYP3A5;CYP3A7;UGT2B7;UGT1A1;ABCB1;RALBP1;ABCC2 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport NR1I2;ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC1;RALBP1 GO:0006629| lipid metabolic process UGT2B7;CYP2C9;CYP1A2;FDPS;CYP3A4 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A7;UGT2B7;CYP3A5;CYP3A4;CYP1A2;FDPS;NR1I2;CYP2B6;CYP2C9 GO:0006810| transport ABCC2;ABCB1;ABCC1 GO:0055085| transmembrane transport RALBP1;SCN5A;ABCC1;ABCC2;ABCB1 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug UGT1A1;ABCC1;CYP1A2;ABCB1;ABCC2 42091:[DB00399 DB00262] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00262|Carmustine GSR;CYP1A2 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS 42092:[DB00399 DB13520] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13520|Metergoline SCN2A common genes common pathways GO:0055085| transmembrane transport SCN2A;ABCC1 42093:[DB00399 DB14019] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14019|Fosnetupitant CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42094:[DB00399 DB09059] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09059|Atosiban OXTR;AVPR1A;AVPR1B;AVPR2 common genes common pathways GO:0042493| response to drug ABCC1;OXTR 42095:[DB00399 DB01454] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01454|Midomafetamine SLC6A4;SLC18A2;SLC6A3;HTR2A;HTR2B;HTR2C;SLC6A2;CYP2D6;SLC6A2;SLC6A3;SLC6A4 common genes common pathways GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0055085| transmembrane transport SLC6A4;SLC6A3;SLC6A2;ABCC1;SLC18A2 GO:0006810| transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0042493| response to drug SLC6A3;HTR2A;HTR2B;SLC6A2;ABCC1;HTR2C;SLC6A4 42096:[DB00399 DB00204] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00204|Dofetilide KCNH2;KCNK2;KCNJ12;CYP3A4;SLC22A2 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport KCNH2;ABCC1;SLC22A2 GO:0006855| drug transmembrane transport ABCC1;SLC22A2 GO:0006629| lipid metabolic process FDPS;CYP3A4 42097:[DB00399 DB05459] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05459|Briakinumab IL12B;IL23A common genes common pathways 42098:[DB00399 DB00813] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00813|Fentanyl OPRM1;OPRD1;OPRK1;ABCB1;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 42099:[DB00399 DB00914] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00914|Phenformin PRKAA1;KCNJ8;CYP2D6;SLC22A2;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A1 GO:0006629| lipid metabolic process PRKAA1;FDPS;CYP2D6 GO:0016126| sterol biosynthetic process PRKAA1;FDPS GO:0055085| transmembrane transport SLC22A2;ABCC1;SLC22A1 GO:0008202| steroid metabolic process PRKAA1;FDPS;CYP2D6 GO:0006694| steroid biosynthetic process PRKAA1;FDPS GO:0006695| cholesterol biosynthetic process FDPS;PRKAA1;GGPS1 GO:0008203| cholesterol metabolic process PRKAA1;FDPS 42100:[DB00399 DB00620] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00620|Triamcinolone NR3C1;CYP3A4;PTGS2;BCHE;SERPINA6 common genes common pathways GO:0006629| lipid metabolic process PTGS2;CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;PTGS2;BCHE 42101:[DB00399 DB00454] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00454|Meperidine OPRK1;GRIN1;GRIN2B;GRIN2A;GRIN2C;GRIN2D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;OPRM1;SLC6A3;SLC6A2;SLC6A4;CES1;CYP3A4;CYP2C19;CYP2B6;CYP2D6;CYP1A2;ALB;ORM1 common genes common pathways GO:0055085| transmembrane transport SLC6A2;ABCC1;SLC6A3;SLC6A4 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2B6 GO:0006810| transport GRIN2A;GRIN2B;SLC6A2;ABCC1;GRIN2C GO:0042493| response to drug CYP1A2;SLC6A4;GRIN2A;SLC6A3;ABCC1;SLC6A2 GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CES1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6 42102:[DB00399 DB00489] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00489|Sotalol KCNH2;ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0055085| transmembrane transport ABCC1;KCNH2 GO:0008202| steroid metabolic process CYP2D6;FDPS 42103:[DB00399 DB01015] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01015|Sulfamethoxazole GSTP1;NAT1;NAT2;CYP2C9;PTGS1;UGT1A9;CYP2C8;CYP3A4;ALB;ABCB11 common genes common pathways GO:0006629| lipid metabolic process PTGS1;FDPS;CYP2C9;CYP3A4 GO:0055085| transmembrane transport ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP3A4;CYP2C9;FDPS GO:0006810| transport ABCB11;ABCC1 42104:[DB00399 DB00321] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00321|Amitriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;OPRD1;OPRK1;NTRK1;NTRK2;ADRA1A;ADRA1D;ADRA2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCNQ2;KCNA1;KCND2;KCND3;HRH2;HRH4;SIGMAR1;HTR2C;ADRA1B;HTR7;HTR1D;OPRM1;HTR1B;HTR6;KCNQ3;ADRB1;ADRB2;ADRB3;CYP2D6;CYP1A2;CYP2C19;CYP2C9;CYP3A4;CYP3A5;CYP2B6;CYP2C8;CYP2E1;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug SLC6A4;ABCB1;HTR1B;CYP1A2;NTRK1;HTR2C;UGT1A1;SLC6A2;ABCC1;CYP2E1;HTR2A;ADRA1A GO:0055085| transmembrane transport KCND2;KCNQ2;ABCC1;SLC6A2;KCNQ3;SLC6A4;KCND3;ABCB1;KCNA1 GO:0006810| transport ABCB1;SLC6A2;ABCC1 GO:0008202| steroid metabolic process CYP2E1;CYP3A5;UGT1A1;CYP2C8;CYP2C19;CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP3A4 42105:[DB00399 DB02261] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02261|Platelet Activating Factor GM2A;PTAFR;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;GM2A GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 42106:[DB00399 DB00248] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00248|Cabergoline DRD2;HTR2B;DRD3;HTR2A;ADRA2B;HTR1D;DRD4;ADRA2A;HTR1A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;HTR7;ADRA1A;ADRA1B;ADRA1D;ADRB1;ADRB2;DRD1;DRD5;CYP3A4;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction HTR2A;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug DRD3;HTR1B;ABCB1;HTR2C;ABCC1;HTR2B;HTR2A;DRD1;ADRA1A;DRD2 42107:[DB00399 DB00209] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00209|Trospium CHRM1;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0008202| steroid metabolic process FDPS;CYP2D6 42108:[DB00399 DB00730] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00730|Thiabendazole CYP1A2;CYP1A1 common genes common pathways GO:0008202| steroid metabolic process CYP1A1;CYP1A2;FDPS GO:0042493| response to drug CYP1A1;ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP1A2;FDPS 42109:[DB00399 DB04978] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04978|SP1049C TOP2A common genes common pathways 42110:[DB00399 DB00359] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00359|Sulfadiazine CYP2C9;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 GO:0042493| response to drug CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP3A4;FDPS;CYP2C9 42111:[DB00399 DB00761] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00761|Potassium Chloride SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4;SLC12A2;SLC12A1;SLC12A5;SLC12A6;SLC12A7;SLC12A4 common genes common pathways GO:0006810| transport ABCC1;SLC12A7;SLC12A1;SLC12A4;SLC12A2 GO:0055085| transmembrane transport SLC12A2;SLC12A5;SLC12A6;SLC12A1;SLC12A4;SLC12A7;ABCC1 GO:0042493| response to drug ABCC1;SLC12A5 42112:[DB00399 DB01028] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01028|Methoxyflurane GABRA1;GRIA1;GLRA1;ATP2C1;KCNA1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP1A2;CYP2A6;CYP2B6;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCC1;KCNA1 GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRA3;GABRA5;GABRB2;GABRB1;GABRA4;GABRA6;ABCC1;GABRD GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2D6;CYP1A2;FDPS;CYP3A4;CYP2A6;CYP2E1 GO:0042493| response to drug MT-ND1;GABRG3;CYP1A2;ABCC1;CYP2E1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;FDPS 42113:[DB00399 DB11714] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11714|Durvalumab CD274;CD80 common genes common pathways GO:0016032| viral reproduction CD80;FDPS 42114:[DB00399 DB14025] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14025|Clinafloxacin CYP1A2;CYP2C19;CYP2D6;CYP2C9 common genes common pathways GO:0042493| response to drug ABCC1;CYP1A2 GO:0008202| steroid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP2C19 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9 42115:[DB00399 DB14634] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14634|Fluprednidene acetate CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42116:[DB00399 DB06543] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06543|Astaxanthin NFKBIA common genes common pathways GO:0016032| viral reproduction FDPS;NFKBIA 42117:[DB00399 DB00154] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00154|Dihomo-gamma-linolenic acid PTGS1;PTGS2;FABP7 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process PTGS2;PTGS1;FDPS 42118:[DB00399 DB12278] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12278|Propiverine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CACNA1C;ADRA1A;CYP3A4;FMO1;FMO3;CYP2B common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;CACNA1C GO:0042493| response to drug ABCC1;ADRA1A 42119:[DB00399 DB08908] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08908|Dimethyl fumarate KEAP1;RELA common genes common pathways GO:0042493| response to drug ABCC1;RELA GO:0016032| viral reproduction FDPS;RELA 42120:[DB00399 DB05104] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05104|Asimadoline OPRK1 common genes common pathways 42121:[DB00399 DB09071] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09071|Tasimelteon MTNR1A;MTNR1B;CYP3A4;CYP1A2 common genes common pathways GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 42122:[DB00399 DB05706] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05706|13-deoxydoxorubicin TOP2A common genes common pathways 42123:[DB00399 DB02123] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02123|Glycochenodeoxycholic Acid ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0006810| transport ABCB11;ABCC1;SLC10A1;SLC10A2 GO:0055085| transmembrane transport SLC10A2;SLC10A1;ABCC1;SLCO1A2;ABCB11 GO:0016032| viral reproduction SLC10A1;FDPS 42124:[DB00399 DB06335] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06335|Saxagliptin DPP4;CYP3A4;CYP3A5;ABCC1;SLCO4C1;SLC22A8 common genes ABCC1 common pathways GO:0042493| response to drug ABCC1 GO:0006691| leukotriene metabolic process ABCC1 GO:0099133| ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A8;SLCO4C1 GO:0006810| transport ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP3A5 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0034775| glutathione transmembrane transport ABCC1 GO:0006855| drug transmembrane transport ABCC1 GO:0042908| xenobiotic transport ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 42125:[DB00399 DB09076] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09076|Umeclidinium CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6 42126:[DB00399 DB00665] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00665|Nilutamide AR;POR;CYP2C19;CYP2C8 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2C8;FDPS GO:0006810| transport AR;ABCC1 GO:0042493| response to drug ABCC1;POR 42127:[DB00399 DB00977] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00977|Ethinylestradiol ESR1;NR1I2;SHBG;CYP3A4;CYP2C8;UGT1A1;ABCB11;SLC10A1;ABCC2;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction FDPS;SLC10A1 GO:0042908| xenobiotic transport NR1I2;ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1;ABCC2 GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCC1;UGT1A1;ABCB1;ABCC2 GO:0006810| transport ABCC2;ABCB1;SLC10A1;ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP3A4;FDPS;NR1I2;CYP2C8;UGT1A1 GO:0055085| transmembrane transport SLC10A1;ABCB1;ABCC2;ABCB11;ABCC1 42128:[DB00399 DB00246] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00246|Ziprasidone DRD2;HTR2A;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP3A4;CYP2D6;CYP1A2;FDPS GO:0042493| response to drug ABCC1;DRD2;ADRA1A;DRD1;HTR2A;HTR1B;DRD3;HTR2C;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS;CYP1A2 GO:0016032| viral reproduction FDPS;HTR2A 42129:[DB00399 DB00907] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00907|Cocaine SLC6A3;SLC6A2;SLC6A4;SCN5A;SCN11A;SCN10A;CHRM1;CHRM2;SIGMAR1;CES1;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;BCHE;SLC22A2 common genes common pathways GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CES1 GO:0042493| response to drug SLC6A3;ABCC1;SLC6A2;BCHE;SLC6A4;SCN11A GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4;CYP3A5;CYP3A7;CYP2C8 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SCN5A;SLC6A2;ABCC1;SCN10A;SLC6A3;SLC22A2;SCN11A;SLC6A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0006855| drug transmembrane transport SLC22A2;ABCC1 42130:[DB00399 DB05187] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05187|Elafibranor PPARA;PPARD;PPARG common genes common pathways GO:0008203| cholesterol metabolic process PPARD;FDPS GO:0042493| response to drug PPARG;ABCC1 GO:0006629| lipid metabolic process PPARA;PPARD;PPARG;FDPS 42131:[DB00399 DB05838] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05838|OPC-51803 AVPR2 common genes common pathways 42132:[DB00399 DB01355] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01355|Hexobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2C19;CYP2C9;PTGS1;CYP2E1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process PTGS1;FDPS;CYP2C9;CYP3A4 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP3A4;CYP2E1;CYP2C19 GO:0006810| transport GABRA1;GRIK2;GABRA6;GABRA4;ABCC1;GABRA5;GABRA3 GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0042493| response to drug ABCC1;CYP2E1 42133:[DB00399 DB00651] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00651|Dyphylline PDE4B;PDE4A;PDE4C;PDE4D;ADORA1;ADORA2A;PDE7A;PDE7B common genes common pathways GO:0042493| response to drug ADORA2A;ABCC1 42134:[DB00399 DB06230] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06230|Nalmefene OPRM1;OPRK1;OPRD1;UGT2B7;UGT1A3;UGT1A8 common genes common pathways GO:0006629| lipid metabolic process FDPS;UGT2B7 GO:0008202| steroid metabolic process UGT2B7;UGT1A8;FDPS 42135:[DB00399 DB11182] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11182|Rose bengal free acid LYZ;ALB;LTF;TF common genes common pathways 42136:[DB00399 DB00457] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00457|Prazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;ADRA2A;ADRA2B;CYP1A1;ORM1;SLC22A2;SLC22A1;SLC22A3;ABCB1;ABCG2 common genes common pathways GO:0055085| transmembrane transport KCNH2;SLC22A1;ABCB1;SLC22A3;KCNH6;ABCC1;ABCG2;KCNH7;SLC22A2 GO:0008202| steroid metabolic process FDPS;CYP1A1 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0042493| response to drug ABCB1;CYP1A1;ADRA1A;ABCC1;ABCG2 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1;ABCG2 42137:[DB00399 DB09048] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09048|Netupitant TACR1;CYP3A43;CYP2C9;CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9 42138:[DB00399 DB00820] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00820|Tadalafil PDE5A;PDE11A;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5 42139:[DB00399 DB07954] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07954|3-isobutyl-1-methyl-7H-xanthine PDE5A;PDE3B;PDE7A;PDE4D;PDE9A;PDE8A;PDE2A;PDE6G common genes common pathways 42140:[DB00399 DB11363] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11363|Alectinib ALK;ABCB1;ABCG2 common genes common pathways GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1;ABCG2 GO:0042493| response to drug ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 42141:[DB00399 DB08889] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08889|Carfilzomib PSMB5;PSMB8;PSMB1;PSMB9;PSMB2;PSMB10;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0016032| viral reproduction PSMB2;PSMB8;PSMB1;PSMB10;FDPS;PSMB9;PSMB5 GO:0055085| transmembrane transport PSMB9;PSMB5;ABCB1;PSMB2;PSMB8;PSMB10;PSMB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 42142:[DB00399 DB11605] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11605|Myrrh NR1H4;NR1I2;PPARA;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4;PPARA GO:0042908| xenobiotic transport NR1I2;ABCC1 GO:0008202| steroid metabolic process NR1I2;FDPS;CYP3A4;CYP3A5;CYP3A7 42143:[DB00399 DB00687] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00687|Fludrocortisone NR3C2;NR3C1;AR;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport AR;ABCC1 42144:[DB00399 DB09301] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09301|Chondroitin sulfate BDNF;GDNF;VEGFA;CCL2;GUSB;HEXB;GALNS;IDS;IDUA;ARSB common genes common pathways 42145:[DB00399 DB01137] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01137|Levofloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;ABCB1;SLC22A6;SLC22A2;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCB1;SLC47A2;SLC47A1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC47A2;SLC22A4;SLC47A1;ABCC1;SLC22A2;SLC22A6 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug CYP1A2;ABCB1;ABCC1 42146:[DB00399 DB01544] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01544|Flunitrazepam TSPO;GABRA2;GABRA4;GABRA5;GABRA6;GABRA3;GABRA1;GABRB3;GABRG2;CYP2C19;UGT2B7;CYP2A6;CYP2B6;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT1A3 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4;UGT2B7 GO:0006810| transport GABRG2;GABRA1;GABRB3;ABCC1;GABRA6;GABRA4;GABRA3;GABRA5 GO:0008202| steroid metabolic process CYP2E1;UGT2B7;UGT1A1;CYP2C19;CYP2B6;CYP2C9;TSPO;FDPS;CYP2A6;CYP3A4 GO:0006694| steroid biosynthetic process TSPO;FDPS GO:0042493| response to drug TSPO;ABCC1;UGT1A1;CYP2E1 42147:[DB00399 DB01192] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01192|Oxymorphone OPRM1;OPRD1;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 42148:[DB00399 DB09477] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09477|Enalaprilat ACE;BDKRB1 common genes common pathways 42149:[DB00399 DB08795] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08795|Azidocillin SLC22A5;SLC15A1;SLC15A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCC1 GO:0006810| transport SLC15A1;ABCC1;SLC15A2 GO:0055085| transmembrane transport SLC15A1;ABCC1;SLC22A5;SLC15A2 42150:[DB00399 DB09240] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09240|Niludipine CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42151:[DB00399 DB13879] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13879|Glecaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B3;ABCG2;ABCC1;SLCO1B1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;UGT1A1;FDPS;CYP3A4 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0042493| response to drug ABCB1;ABCG2;UGT1A1;ABCC1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 42152:[DB00399 DB00571] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C19;CYP3A7;CYP3A5;CYP1A1 GO:0055085| transmembrane transport SLC22A2;ABCC1;ABCB1 GO:0042493| response to drug CYP1A1;ABCC1;CYP1A2;HTR1B;ABCB1 42153:[DB00399 DB05971] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05971|Archexin AKT1 common genes common pathways 42154:[DB00399 DB12629] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12629|3,5-diiodothyropropionic acid CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 42155:[DB00399 DB06240] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06240|Tariquidar ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 42156:[DB00399 DB00806] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00806|Pentoxifylline PDE4B;ADORA1;PDE5A;PDE4A;ADORA2A;NT5E;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0042493| response to drug CYP1A2;ADORA2A;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 42157:[DB00399 DB01273] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01273|Varenicline CHRNA4;CHRNA7;CHRNA3;CHRNA6;CHRNB2;SLC22A2 common genes common pathways GO:0006810| transport CHRNA6;ABCC1 GO:0055085| transmembrane transport SLC22A2;ABCC1 GO:0006855| drug transmembrane transport ABCC1;SLC22A2 42158:[DB00399 DB07447] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07447|5beta-dihydrotestosterone AKR1D1 common genes common pathways GO:0006629| lipid metabolic process FDPS;AKR1D1 GO:0008202| steroid metabolic process FDPS;AKR1D1 42159:[DB00399 DB11752] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11752|Bryostatin 1 CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 42160:[DB00399 DB00498] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00498|Phenindione VKORC1 common genes common pathways 42161:[DB00399 DB14146] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14146|Loxicodegol OPRM1;OPRD1;OPRK1;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 42162:[DB00399 DB04903] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04903|Pagoclone GABRA2;GABRA3 common genes common pathways GO:0006810| transport ABCC1;GABRA3 42163:[DB00399 DB00727] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00727|Nitroglycerin NPR1;ALDH2 common genes common pathways 42164:[DB00399 DB00951] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00951|Isoniazid katG;CYP2C8;CYP1A2;CYP3A4;CYP2C19;CYP3A4;CYP2E1;CYP2C9;CYP1A2;CYP2D6;CYP2C19;NAT2;CYP2A6;CYP2C8;ALB common genes common pathways GO:0042493| response to drug CYP2E1;ABCC1;CYP1A2 GO:0008202| steroid metabolic process CYP2E1;CYP2C8;CYP2C19;CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4;CYP2A6 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6 42165:[DB00399 DB00988] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00988|Dopamine DRD2;DRD1;DRD5;DRD3;DRD4;SLC6A3;DBH;HTR1A;HTR7;DRD1;DRD5;SLC6A2;SLC6A4;HTR3A;HTR3B;SOD1;SLC18A2;MAOA;MAOB;COMT;DBH;CYP2C19;SLC22A2;SLC22A1;SLC22A3;SLC22A5;POU5F1 common genes common pathways GO:0042493| response to drug DRD1;SOD1;DRD2;SLC6A3;MAOB;SLC6A2;ABCC1;COMT;SLC6A4;DRD3 GO:0055085| transmembrane transport SLC22A3;SLC22A1;SLC6A4;SLC22A2;SLC6A3;SLC22A5;ABCC1;SLC6A2;SLC18A2 GO:0008202| steroid metabolic process FDPS;CYP2C19 GO:0006810| transport ABCC1;SLC6A2 GO:0006855| drug transmembrane transport SLC22A5;SLC22A2;ABCC1;SLC22A3;SLC22A1 42166:[DB00399 DB00317] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00317|Gefitinib EGFR;CYP3A4;CYP2D6;CYP3A5;CYP1A1;CYP2C9;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP1A1;CYP3A5;CYP2C19;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0042493| response to drug CYP1A1;ABCG2;ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;FDPS 42167:[DB00399 DB00433] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00433|Prochlorperazine DRD2;CYP2D6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042493| response to drug ABCC1;DRD2 GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 42168:[DB00399 DB01184] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01184|Domperidone DRD2;DRD3;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2B6;CYP2D6;CYP3A4;CYP3A7;CYP3A5;CYP2C8 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug DRD2;ABCC1;CYP1A2;ABCB1;DRD3 42169:[DB00399 DB11915] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11915|Valbenazine VMAT2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS;CYP2D6 42170:[DB00399 DB01579] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01579|Phendimetrazine ADRA1A;SLC6A2;ADRA1B common genes common pathways GO:0042493| response to drug ADRA1A;ABCC1;SLC6A2 GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport ABCC1;SLC6A2 42171:[DB00399 DB05964] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05964|Amitifadine SLC6A4;SLC6A2;DRD2 common genes common pathways GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A4;ABCC1;SLC6A2 GO:0042493| response to drug SLC6A4;DRD2;ABCC1;SLC6A2 42172:[DB00399 DB06663] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06663|Pasireotide SSTR1;SSTR2;SSTR3;SSTR5;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 42173:[DB00399 DB00082] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00082|Pegvisomant GHR;CYP27A1;GLUL;CYP2C18;CYP3A4;BCHE;CYP2C19;CYP4A11 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP3A4 GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 GO:0042493| response to drug BCHE;ABCC1 42174:[DB00399 DB06196] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06196|Icatibant BDKRB2;ANPEP common genes common pathways GO:0016032| viral reproduction ANPEP;FDPS 42175:[DB00399 DB01442] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01442|MMDA HTR2A;SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;MAOA;MAOB common genes common pathways GO:0042493| response to drug HTR2A;SLC6A3;MAOB;SLC6A2;ABCC1;SLC6A4 GO:0055085| transmembrane transport SLC6A4;SLC6A3;SLC18A1;SLC18A2;SLC6A2;ABCC1 GO:0006810| transport SLC6A2;ABCC1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006855| drug transmembrane transport SLC18A1;ABCC1 42176:[DB00399 DB00899] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00899|Remifentanil OPRM1;OPRD1;OPRK1 common genes common pathways 42177:[DB00399 DB00218] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00218|Moxifloxacin parC;gyrA;TOP2A;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0042493| response to drug ABCC1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS 42178:[DB00399 DB01103] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01103|Quinacrine PLA2G6;PLA2G4A;PLCL1;HNMT;CYP3A4;CYP3A5;SLC22A2;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;PLA2G4A;PLCL1;PLA2G6 GO:0055085| transmembrane transport ABCB1;ABCC1;SLC22A2 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP3A5 GO:0042493| response to drug ABCC1;ABCB1 42179:[DB00399 DB13165] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13165|Ripasudil ROCK1;ROCK2 common genes common pathways 42180:[DB00399 DB00686] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00686|Pentosan Polysulfate FGF2;FGF1;FGF4 common genes common pathways 42181:[DB00399 DB06203] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06203|Alogliptin DPP4;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 42182:[DB00399 DB00245] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00245|Benzatropine CHRM1;SLC6A3;HRH1;CYP2C19;CYP2D6 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC6A3 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP2C19 GO:0042493| response to drug ABCC1;SLC6A3 GO:0006629| lipid metabolic process CYP2D6;FDPS 42183:[DB00399 DB14070] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14070|HM-30181 ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 42184:[DB00399 DB03477] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03477|1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole PTGS2 common genes common pathways GO:0042493| response to drug ABCC1;PTGS2 GO:0006629| lipid metabolic process PTGS2;FDPS 42185:[DB00399 DB11156] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11156|Pyrantel GPR35;CHRM1;CYP4A11 common genes common pathways GO:0006691| leukotriene metabolic process CYP4A11;ABCC1 42186:[DB00399 DB08935] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08935|Obinutuzumab MS4A1 common genes common pathways 42187:[DB00399 DB05131] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05131|TTP889 F9 common genes common pathways 42188:[DB00399 DB09546] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09546|Iobenguane sulfate I-123 SLC6A2 common genes common pathways GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport SLC6A2;ABCC1 GO:0042493| response to drug ABCC1;SLC6A2 42189:[DB00399 DB08964] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08964|Gemeprost PTGER2;PTGER3 common genes common pathways 42190:[DB00399 DB08496] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08496|(R)-warfarin CYP2C8;CYP2C9;CYP2C18;CYP2C19;CYP1A2;CYP1A1;CYP3A4;ALB common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP1A1 GO:0042493| response to drug ABCC1;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP1A2;CYP3A4 42191:[DB00399 DB08879] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08879|Belimumab TNFSF13B common genes common pathways 42192:[DB00399 DB05804] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05804|Prasterone sulfate CYP19A1;CYP3A7;PTGS2;SLC22A8;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC10A6;ABCB11 common genes common pathways GO:0006629| lipid metabolic process PTGS2;FDPS GO:0055085| transmembrane transport SLCO1B3;SLCO2B1;SLC10A6;SLCO1B1;SLC22A8;ABCB11;ABCC1;SLCO1A2 GO:0006810| transport ABCB11;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A7 GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0042493| response to drug ABCC1;PTGS2 42193:[DB00399 DB00970] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00970|Dactinomycin TOP2A;TOP2B;SLC22A5;ABCB1;ABCC6;ABCC1;ABCG2 common genes ABCC1 common pathways GO:0006855| drug transmembrane transport SLC22A5;ABCG2;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0099039| ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0015889| cobalamin transport ABCC1 GO:0034775| glutathione transmembrane transport ABCC1 GO:0055085| transmembrane transport SLC22A5;ABCC6;ABCC1;ABCG2;ABCB1 GO:0006810| transport ABCB1;ABCC6;ABCC1;ABCG2 GO:0009235| cobalamin metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0099133| ABCC1;ABCC6 GO:0006691| leukotriene metabolic process ABCC1 GO:0042493| response to drug ABCB1;ABCC6;ABCC1;ABCG2 42194:[DB00399 DB13074] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13074|Macimorelin GHSR;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 42195:[DB00399 DB11133] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11133|Omega-3 fatty acids PPARG;PPARA;SREBF1;PTGS2;ALOX5 common genes common pathways GO:0008202| steroid metabolic process SREBF1;FDPS GO:0045540| regulation of cholesterol biosynthetic process SREBF1;FDPS;GGPS1 GO:0008203| cholesterol metabolic process SREBF1;FDPS GO:0006691| leukotriene metabolic process ABCC1;ALOX5 GO:0042493| response to drug PTGS2;SREBF1;ABCC1;PPARG GO:0006629| lipid metabolic process PPARG;PPARA;FDPS;SREBF1;PTGS2 42196:[DB00399 DB01353] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01353|Butethal GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0055085| transmembrane transport GRIK2;ABCC1 GO:0006810| transport GABRA5;GABRA3;GABRA4;GABRA6;GRIK2;ABCC1;GABRA1 42197:[DB00399 DB00230] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00230|Pregabalin CACNA1A;CYP3A4;SLC1A1 common genes common pathways GO:0055085| transmembrane transport CACNA1A;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 42198:[DB00399 DB12301] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12301|Doravirine pol;CYP3A4;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS 42199:[DB00399 DB00758] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00758|Clopidogrel P2RY12;CYP3A4;CYP2B6;CYP3A5;CYP2C19;CYP2C9;CYP1A2;CYP2C8;CES1;ABCB1;SLC22A1;SLC22A2 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP3A4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;SLC22A2;SLC22A1;ABCB1 GO:0006695| cholesterol biosynthetic process GGPS1;FDPS;CES1 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2B6;CYP1A2;FDPS;CYP2C8;CYP2C19;CYP3A5 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A2;ABCB1;SLC22A1 42200:[DB00399 DB13174] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13174|Rhein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;CYP2E1;ABCC1 GO:0006691| leukotriene metabolic process ALOX5;ABCC1 GO:0008202| steroid metabolic process CYP3A7;CYP2E1;CYP3A5;CYP3A4;CYP1A2;FDPS;CYP2C9;CYP2D6 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 42201:[DB00399 DB05099] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05099|Ancrod FGA common genes common pathways 42202:[DB00399 DB11738] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11738|Rilmenidine ADRA2A common genes common pathways 42203:[DB00399 DB00588] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00588|Fluticasone propionate NR3C1;PGR;PLA2G4A;NR3C2;CYP3A4;CYP3A5;CYP3A7;CYP2C8;SERPINA6;ABCB1;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP3A5;CYP3A7;CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;PLA2G4A;CYP3A4 42204:[DB00399 DB08828] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08828|Vismodegib SMO;CYP2C9;CYP3A4;CYP2C8;CYP2C19;ALB;ORM1;ABCB1;ABCG2 common genes common pathways GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP3A4;CYP2C19;CYP2C8 GO:0055085| transmembrane transport ABCB1;ABCC1;ABCG2 GO:0042493| response to drug ABCB1;ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 42205:[DB00399 DB07449] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07449|N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE PADI4 common genes common pathways 42206:[DB00399 DB00388] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00388|Phenylephrine ADRA1A;ADRA1B;ADRA1D;MAOA;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;ADRA1A;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A2 42207:[DB00399 DB00819] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00819|Acetazolamide CA1;CA2;CA4;CA12;CA14;CA3;CA7;AQP1;CYP3A4;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport SLC22A6;AQP1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;AQP1 42208:[DB00399 DB00284] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00284|Acarbose MGAM;AMY2A;GAA;SI common genes common pathways 42209:[DB00399 DB01067] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01067|Glipizide ABCC8;PPARG;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0008202| steroid metabolic process UGT1A1;CYP2C9;FDPS;CYP3A4 GO:0006810| transport ABCB11;ABCC1 GO:0055085| transmembrane transport ABCB11;ABCC8;ABCC1 GO:0099133| ABCC1;ABCC8 GO:0042493| response to drug PPARG;ABCC8;UGT1A1;ABCC1 GO:0006629| lipid metabolic process CYP2C9;FDPS;PPARG;CYP3A4 42210:[DB00399 DB01159] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01159|Halothane KCNK3;KCNK9;KCNMA1;GRIN3A;GRIN3B;GRIN2A;GLRA1;RHO;KCNJ6;KCNJ3;MT-ND1;KCNN4;ATP2C1;GABRA1;GNG2;NPSR1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP3A4;CYP2A6;CYP2B6;CYP2C9;ALB common genes common pathways GO:0006810| transport GABRB3;GABRA1;GRIN2A;GABRG2;GABRA3;GABRA5;GABRB2;GABRB1;GABRA4;GABRA6;ABCC1;GABRD GO:0008202| steroid metabolic process CYP2E1;CYP3A4;CYP2A6;CYP2C9;CYP2B6;FDPS GO:0055085| transmembrane transport KCNMA1;ABCC1 GO:0042493| response to drug KCNK3;GABRG3;GRIN2A;MT-ND1;CYP2E1;ABCC1 GO:0045332| phospholipid translocation ABCC1;KCNN4 GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 42211:[DB00399 DB05889] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05889|Inotuzumab ozogamicin CD22;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 42212:[DB00399 DB01013] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01013|Clobetasol propionate NR3C1;CYP1A1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;FDPS;CYP3A4 42213:[DB00399 DB04868] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04868|Nilotinib ABL1;KIT;CYP3A4;CYP2C8;CYP2C9;CYP2D6;CYP2B6;ABCB1;ABCG2;UGT1A1;SLCO1B1 common genes common pathways GO:0055085| transmembrane transport ABCB1;SLCO1B1;ABCG2;ABCC1 GO:0006810| transport ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;FDPS;CYP2D6;CYP2C9;CYP2B6;CYP3A4 GO:0060326| cell chemotaxis ABCC1;KIT GO:0042493| response to drug ABCC1;UGT1A1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C9 42214:[DB00399 DB06235] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06235|Vadimezan UGT1A9;UGT2B7;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process UGT2B7;FDPS;CYP1A2 GO:0042493| response to drug CYP1A2;ABCC1 GO:0008202| steroid metabolic process CYP1A2;FDPS;UGT2B7 42215:[DB00399 DB14066] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14066|Tetrandrine ABCB1;CYP3A4 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 42216:[DB00399 DB00703] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00703|Methazolamide CA1;CA2;CA4;CA7;CA3;CYP2C19;CYP2D6;CYP2E1;CYP3A4;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0042493| response to drug ABCC1;CYP2E1 GO:0055085| transmembrane transport ABCC1;SLC22A6 GO:0008202| steroid metabolic process CYP2E1;CYP2C19;FDPS;CYP2D6;CYP3A4 42217:[DB00399 DB00337] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00337|Pimecrolimus MTOR;FKBP1A;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 42218:[DB00399 DB01069] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01069|Promethazine HRH1;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;HTR2A;CALM1;HRH2;CYP2D6;CYP2B6;CYP2C9;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP2D6 GO:0055085| transmembrane transport ABCB1;ABCC1;CALM1 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP2D6;FDPS GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;HTR2A;DRD2;ADRA1A;ABCC1 42219:[DB00399 DB00203] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00203|Sildenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2D6;CYP1A1;CYP2E1;ABCC4;ABCC5;ABCC10;SLCO1B1;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0099133| ABCC5;ABCC4;ABCC1;ABCC10 GO:0042493| response to drug ABCC1;CYP1A1;CYP2E1;ABCB1;ABCC4 GO:0055085| transmembrane transport ABCC10;SLCO1B1;ABCC1;ABCC4;ABCB1;ABCC5 GO:0008202| steroid metabolic process CYP1A1;CYP3A5;CYP3A7;CYP2E1;CYP2C19;CYP2C9;CYP2D6;FDPS;CYP3A4 GO:0006810| transport ABCC1;ABCC5;ABCB1 42220:[DB00399 DB06470] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06470|Clomethiazole GABRA1;CYP2A6;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2A6;CYP3A4;FDPS;CYP2B6 GO:0006810| transport GABRA1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS 42221:[DB00399 DB01340] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01340|Cilazapril ACE;ABCB1;SLC15A1;SLC15A2 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport SLC15A2;ABCC1;SLC15A1;ABCB1 GO:0006810| transport ABCB1;SLC15A1;ABCC1;SLC15A2 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 42222:[DB00399 DB01042] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01042|Melphalan SLC22A3;SLC7A5 common genes common pathways GO:0006810| transport ABCC1;SLC7A5 GO:0055085| transmembrane transport ABCC1;SLC22A3 GO:0006855| drug transmembrane transport ABCC1;SLC22A3 42223:[DB00399 DB05297] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05297|Paclitaxel docosahexaenoic acid BCL2 common genes common pathways GO:0042493| response to drug ABCC1;BCL2 GO:0055085| transmembrane transport ABCC1;BCL2 42224:[DB00399 DB00009] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00009|Alteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 42225:[DB00399 DB07285] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07285|(3R)-4,4-DIFLUORO-3-[(4-METHOXYPHENYL)SULFONYL]BUTANOIC ACID MMP9 common genes common pathways 42226:[DB00399 DB01001] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01001|Salbutamol ADRB2;ADRB1;ADRB3;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42227:[DB00399 DB01002] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01002|Levobupivacaine SCN10A;CYP3A4;CYP1A2 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS GO:0055085| transmembrane transport SCN10A;ABCC1 GO:0042493| response to drug ABCC1;CYP1A2 42228:[DB00399 DB04842] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04842|Fluspirilene DRD2;HTR2A;CACNG1;CYP3A4 common genes common pathways GO:0006810| transport ABCC1;CACNG1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug DRD2;HTR2A;ABCC1 GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process FDPS;CYP3A4 42229:[DB00399 DB01392] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01392|Yohimbine ADRA2A;ADRA2B;ADRA2C;HTR1A;HTR1B;HTR1D;DRD2;DRD3;HTR2A;HTR2C;KCNJ1;KCNJ10;KCNJ11;KCNJ12;KCNJ14;KCNJ15;KCNJ8;HTR2B;CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0016032| viral reproduction FDPS;HTR2A GO:0042493| response to drug HTR2A;DRD2;KCNJ11;ABCC1;HTR2B;HTR2C;DRD3;HTR1B GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0055085| transmembrane transport ABCC1;KCNJ11 42230:[DB00399 DB01809] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01809|1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine HCK;RET common genes common pathways GO:0042493| response to drug RET;ABCC1 GO:0016032| viral reproduction FDPS;HCK 42231:[DB00399 DB00591] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00591|Fluocinolone acetonide NR3C1;ANXA1;ANXA2;ANXA3;ANXA4;ANXA5;CYP3A4;SERPINA6 common genes common pathways GO:0042493| response to drug ANXA1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42232:[DB00399 DB01549] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01549|Rolicyclidine GRIN3A;DRD2 common genes common pathways GO:0042493| response to drug ABCC1;DRD2 42233:[DB00399 DB06788] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06788|Histrelin GNRHR common genes common pathways 42234:[DB00399 DB01142] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01142|Doxepin HRH1;HRH2;SLC6A2;SLC6A4;HTR2A;HTR2B;HTR2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR1A;ADRA2A;ADRA2B;ADRA2C;DRD2;HTR6;HRH4;KCNH2;CYP2D6;CYP2C19;CYP2C9;CYP1A2;CYP3A4;ORM1;ABCB1 common genes common pathways GO:0006810| transport ABCB1;ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2;CYP2C19 GO:0055085| transmembrane transport SLC6A4;KCNH2;ABCB1;SLC6A2;ABCC1 GO:0042493| response to drug ADRA1A;DRD2;HTR2A;SLC6A2;ABCC1;HTR2B;HTR2C;CYP1A2;ABCB1;SLC6A4 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP2C9;CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0016032| viral reproduction FDPS;HTR2A 42235:[DB00399 DB05271] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05271|Rotigotine DRD3;DRD4;DRD5;DRD2;DRD1;HTR1A;ADRA2B;CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042493| response to drug DRD3;ABCC1;DRD2;DRD1 42236:[DB00399 DB00904] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00904|Ondansetron HTR3A;HTR4;OPRM1;HTR1A;HTR1B;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP2C9;CYP2E1 common genes common pathways GO:0042493| response to drug HTR1B;CYP1A2;ABCC1;CYP2E1 GO:0008202| steroid metabolic process CYP3A5;CYP2E1;CYP3A7;CYP2C9;CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6;CYP2C9;CYP3A4 42237:[DB00399 DB12483] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12483|Copanlisib PIK3CA;PIK3CD;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;ABCB1;ABCG2;SLC47A2 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;ABCC1 GO:0060326| cell chemotaxis PIK3CA;ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP3A7;CYP3A4;FDPS GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCG2;SLC47A2;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006855| drug transmembrane transport SLC47A2;ABCB1;ABCG2;ABCC1 42238:[DB00399 DB11693] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11693|Voclosporin PPP3R1;PPP3R2 common genes common pathways 42239:[DB00399 DB05152] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05152|NGX267 CHRM1 common genes common pathways 42240:[DB00399 DB11529] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11529|Melengestrol CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 42241:[DB00399 DB01931] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01931|Dcka, 5,7-Dichlorokynurenic Acid GRIN1 common genes common pathways 42242:[DB00399 DB02659] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02659|Cholic Acid FECH;ADH1C;ESRRG;FABP6;COX4I1;MT-CO1;MT-CO2;MT-CO3;COX5A;COX5B;COX6C;COX7B;COX7C;COX8A;COX6A2;COX6B1;COX7A1;PLA2G1B;CES1;DKFZp686P18130;NR1H4;GPBAR1;FABP1;ABCB11;ABCB1;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;SLC10A1;SLC22A8;SLC22A7;SLCO1B3 common genes ABCC1 common pathways GO:0006695| cholesterol biosynthetic process CES1;FDPS;GGPS1 GO:0060326| cell chemotaxis ABCC1 GO:0099133| ABCC1;ABCC2;ABCC3;ABCC4 GO:0042493| response to drug ABCC1;FECH;ABCB1;ABCC2;ABCC4 GO:0006691| leukotriene metabolic process ABCC1 GO:0009235| cobalamin metabolic process ABCC1 GO:0006810| transport ABCB1;ABCC2;ABCC3;SLC10A2;SLC10A1;ABCC1;ABCB11 GO:0055085| transmembrane transport SLC10A1;SLC10A2;ABCC3;ABCC4;SLCO1B3;ABCC2;ABCB1;SLC22A7;SLC22A8;ABCB11;SLCO1B1;ABCC1;SLCO1A2 GO:0034775| glutathione transmembrane transport ABCC1 GO:0006629| lipid metabolic process FDPS;PLA2G1B;FABP6 GO:0016032| viral reproduction FDPS;SLC10A1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCC3;ABCB1 GO:0006855| drug transmembrane transport ABCC3;ABCC2;ABCB1;ABCC1 42243:[DB00399 DB01189] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01189|Desflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;ALB common genes common pathways GO:0006810| transport GABRD;ABCC1;GABRA6;GABRA4;GABRB1;GABRB2;GABRA5;GABRA3;GABRG2;GABRB3;GABRA1 GO:0055085| transmembrane transport ABCC1;KCNA1 GO:0042493| response to drug GABRG3;MT-ND1;ABCC1 42244:[DB00399 DB05110] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05110|VIR201 IFNG common genes common pathways 42245:[DB00399 DB00432] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00432|Trifluridine TYMS;TK1;TYMP;ALB;SLC22A6;SLC28A1;SLC29A1;SLC29A2 common genes common pathways GO:0042493| response to drug ABCC1;TYMS GO:0055085| transmembrane transport ABCC1;SLC22A6 42246:[DB00399 DB12116] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12116|Epigallocatechin gallate AHR;DNMT1 common genes common pathways 42247:[DB00399 DB00307] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00307|Bexarotene RXRA;RXRB;RXRG;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4 GO:0016032| viral reproduction FDPS;RXRA GO:0008203| cholesterol metabolic process FDPS;RXRA GO:0008202| steroid metabolic process CYP2C8;FDPS;CYP2C9;CYP3A4 42248:[DB00399 DB02309] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02309|5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine ATIC;HPRT1 common genes common pathways 42249:[DB00399 DB00731] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00731|Nateglinide ABCC8;PPARG;CYP2C9;CYP3A4;CYP3A5;CYP3A7;PTGS1;UGT1A9;CYP2D6;ALB;ORM1;ABCC4;SLC16A1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process FDPS;SLC16A1;CYP2C9;CYP2D6;CYP3A4;PPARG;PTGS1 GO:0042493| response to drug ABCC8;ABCC1;ABCC4;PPARG GO:0099133| ABCC4;ABCC1;ABCC8 GO:0006810| transport SLC15A2;ABCC1;SLC15A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP3A5;CYP3A7 GO:0055085| transmembrane transport SLC22A6;SLC15A2;ABCC1;ABCC8;SLC15A1;ABCC4;SLC16A1 42250:[DB00399 DB04932] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04932|Defibrotide ADORA1;ADORA2A;ADORA2B common genes common pathways GO:0042493| response to drug ABCC1;ADORA2A 42251:[DB00399 DB00334] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00334|Olanzapine HTR2A;DRD2;DRD1;DRD5;DRD3;DRD4;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR5A;DRD1;DRD5;HRH2;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;ADRB1;ADRB2;ADRB3;CYP1A2;CYP2D6;FMO3;CYP2C19;CYP3A4;UGT1A1;ALB;ORM1;ABCB1 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;UGT1A1;FDPS;CYP1A2;CYP2D6;CYP3A4 GO:0006810| transport GABRA4;GABRA6;GABRB1;GABRD;ABCC1;GABRB2;GABRA5;GABRA3;GABRG2;ABCB1;GABRA1;GABRB3 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug GABRG3;DRD3;ABCB1;HTR1B;CYP1A2;HTR2C;UGT1A1;ABCC1;HTR2B;HTR2A;DRD1;DRD2;ADRA1A GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0016032| viral reproduction FDPS;HTR2A 42252:[DB00399 DB00783] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00783|Estradiol ESR1;ESR2;NR1I2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP3A4;CYP1A2;CYP3A5;CYP3A7;UGT1A1;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1;NR1I2 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2;ABCC1;ABCG2 GO:0006629| lipid metabolic process CYP3A4;HSD17B2;CYP1A2;FDPS;CYP2C9 GO:0016032| viral reproduction FDPS;BECN1 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process UGT1A1;CYP2C8;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP1B1;CYP3A4;NR1I2;CYP2C9;CYP1A2;FDPS GO:0055085| transmembrane transport SLC22A3;SLCO1B3;ABCB1;SLCO1C1;SLC22A1;SLC22A2;SLCO2B1;SLCO4A1;SLC22A8;ABCC10;SLCO1B1;ABCG2;ABCC1;SLC22A11;SLCO1A2 GO:0006694| steroid biosynthetic process FDPS;HSD17B2 GO:0099133| ABCC1;ABCC10 GO:0042493| response to drug ABCB1;CYP1A2;ABCC1;UGT1A1;ABCG2;CYP1A1;BECN1 42253:[DB00399 DB14543] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14543|Hydrocortisone probutate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP11B2;CYP11B1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCG2;ABCC1 GO:0042493| response to drug ABCG2;ABCC1;ABCB1;HSD11B2;ANXA1 GO:0006694| steroid biosynthetic process FDPS;CYP11B2;HSD3B1;CYP11B1 GO:0006810| transport ABCG2;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP11B2;CYP3A5;CYP3A7;CYP11B1;CYP3A4;FDPS GO:0055085| transmembrane transport ABCB1;SLC22A8;SLCO1A2;ABCC1;ABCG2 42254:[DB00399 DB01221] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01221|Ketamine GRIN3A;TACR1;DRD2;OPRD1;SLC6A2;OPRK1;OPRM1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2B;HTR2C;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR3A;CHRNA7;BCHE;NOS1;CYP2C9;CYP3A4;CYP2B6;PTGS1;CYP2C8 common genes common pathways GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process PTGS1;CYP3A4;CYP2C9;FDPS GO:0055085| transmembrane transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP3A4;CYP2C9;CYP2B6;FDPS;CYP2C8 GO:0006810| transport ABCC1;SLC6A2 GO:0042493| response to drug HTR1B;BCHE;HTR2C;SLC6A2;ABCC1;HTR2B;HTR2A;DRD2 42255:[DB00399 DB05541] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05541|Brivaracetam SV2A;SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B;CYP3A4;CYP2C19;CYP2B6;CYP2C9 common genes common pathways GO:0042493| response to drug SCN11A;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP2B6;CYP2C9;FDPS;CYP3A4 GO:0055085| transmembrane transport SCN3A;SCN9A;SCN1A;SCN10A;SV2A;ABCC1;SCN4A;SCN5A;SCN2A;SCN8A;SCN7A;SCN11A GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 42256:[DB00399 DB06678] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06678|Esmirtazapine HRH1;HTR2A;HTR2B;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS GO:0016032| viral reproduction HTR2A;FDPS GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0042493| response to drug HTR2C;HTR2A;HTR2B;ABCC1 42257:[DB00399 DB09283] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09283|Trapidil PDE1A;PDE1B;PDE1C;PDE10A;PDE4A;PDE4B;PDE4C;PDE4D;PDE7B;PDE2A;PDE3A;PDE3B;PDE5A;PDE6C;PDE11A;PDE7A;PDE8A;PDE8B;PDE9A;PDE6A;PDE6B common genes common pathways GO:0006629| lipid metabolic process FDPS;PDE3A GO:0042493| response to drug PDE3A;ABCC1 42258:[DB00399 DB00740] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00740|Riluzole SCN5A;SLC7A11;CYP1A2;CYP1A1;ABCG2 common genes common pathways GO:0042493| response to drug CYP1A2;CYP1A1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP1A1;FDPS;CYP1A2 GO:0006810| transport ABCG2;ABCC1 GO:0055085| transmembrane transport SCN5A;ABCG2;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP1A2 GO:0042908| xenobiotic transport ABCC1;ABCG2 GO:0006855| drug transmembrane transport ABCC1;ABCG2 42259:[DB00399 DB09317] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09317|Synthetic Conjugated Estrogens, A ESR1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42260:[DB00399 DB14067] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14067|Dofequidar ABCB5;ABCB1 common genes common pathways GO:0042493| response to drug ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1;ABCB5 GO:0042908| xenobiotic transport ABCB5;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB5;ABCC1;ABCB1 42261:[DB00399 DB00297] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00297|Bupivacaine SCN10A;PTGER1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP2D6;FDPS;CYP3A4 GO:0055085| transmembrane transport SCN10A;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 42262:[DB00399 DB11994] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11994|Diacerein NR1H3;NR1H2;ALOX5;CYP1A2;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2E1;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug CYP1A2;ABCC1;CYP2E1 GO:0006691| leukotriene metabolic process ABCC1;ALOX5 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A5;CYP2E1;CYP3A7 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 42263:[DB00399 DB04841] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04841|Flunarizine CACNA1G;CACNA1H;CACNA1I;HRH1;CALM1;CYP2D6;CYP2C9;CYP1A1;CYP1A2;CYP2A6;CYP3A4 common genes common pathways GO:0042493| response to drug CYP1A2;CYP1A1;ABCC1 GO:0008202| steroid metabolic process CYP1A1;CYP2C9;CYP2D6;CYP1A2;FDPS;CYP3A4;CYP2A6 GO:0006810| transport ABCC1;CACNA1I GO:0055085| transmembrane transport ABCC1;CALM1;CACNA1H;CACNA1I;CACNA1G GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 42264:[DB00399 DB05903] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05903|KOS-1584 CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process FDPS;CYP3A4 42265:[DB00399 DB00491] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00491|Miglitol MGAM;GAA;GANAB;GANC;AMY2A common genes common pathways 42266:[DB00399 DB00853] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00853|Temozolomide CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 42267:[DB00399 DB00335] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00335|Atenolol ADRB1;ADRB2;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB11;ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006810| transport ABCC1;ABCB11;ABCB1 42268:[DB00399 DB14068] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14068|Dexniguldipine ABCB1;CYP3A4 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0042493| response to drug ABCC1;ABCB1 42269:[DB00399 DB01285] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01285|Corticotropin MC2R;CRH;HSD3B2;CYP27B1;CYP24A1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CRH GO:0042493| response to drug CRH;ABCC1 GO:0006694| steroid biosynthetic process HSD3B2;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 42270:[DB00399 DB08896] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08896|Regorafenib FLT1;KDR;FLT4;KIT;PDGFRA;PDGFRB;FGFR1;FGFR2;TEK;DDR2;NTRK1;EPHA2;RAF1;BRAF;MAPK11;FRK;ABL1;RET;CYP3A4;UGT1A9;CYP2C8;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP2B6;CYP3A4;CYP2C8;UGT1A1 GO:0042493| response to drug NTRK1;ABCB1;RET;ABCG2;UGT1A1;ABCC1 GO:0060326| cell chemotaxis PDGFRB;EPHA2;ABCC1;KIT;PDGFRA GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0016032| viral reproduction EPHA2;FDPS;KDR;PDGFRA GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 42271:[DB00399 DB00015] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00015|Reteplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways 42272:[DB00399 DB00752] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00752|Tranylcypromine MAOA;MAOB;CYP3A4;CYP2D6;CYP2C9;CYP2C19;CYP1A2;CYP2E1;CYP2A6 common genes common pathways GO:0042493| response to drug ABCC1;MAOB;CYP2E1;CYP1A2 GO:0008202| steroid metabolic process CYP2C19;CYP2E1;CYP3A4;CYP2A6;FDPS;CYP1A2;CYP2D6;CYP2C9 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 42273:[DB00399 DB09013] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09013|Befunolol ADRB1;ADRB2;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;FDPS GO:0006629| lipid metabolic process CYP2D6;FDPS 42274:[DB00399 DB00277] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00277|Theophylline ADORA1;ADORA2A;ADORA2B;PDE4B;PDE5A;PDE4A;PDE3A;HDAC2;CPNE1;HM13;NOMO1;PARP1;RIC3;TTLL3;CYP3A4;CYP1A2;ADA;CYP2E1;CYP1A1;CYP1B1;CYP2C8;CYP2D6;SLC22A7 common genes common pathways GO:0055085| transmembrane transport SLC22A7;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP1A1;CYP3A4;CYP1B1;FDPS;CYP1A2;CYP2D6 GO:0042493| response to drug HDAC2;ABCC1;ADORA2A;CYP2E1;ADA;PDE3A;CYP1A1;CYP1A2 GO:0006629| lipid metabolic process PDE3A;FDPS;CYP1A2;CYP2D6;CYP3A4;CPNE1 42275:[DB00399 DB12789] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12789|Dinoprost PTGDR2 common genes common pathways 42276:[DB00399 DB01244] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01244|Bepridil CACNA1A;CACNA1H;CACNA2D2;ATP1A1;KCNQ1;TNNC1;CALM1;PDE1B;PDE1A;KCNH2;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCC1;ATP1A1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport CACNA1A;KCNH2;ABCB1;KCNQ1;CALM1;CACNA1H;ABCC1 42277:[DB00399 DB01175] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01175|Escitalopram SLC6A4;SLC6A3;SLC6A2;ADRA1A;CHRM1;HRH1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0042493| response to drug SLC6A4;SLC6A2;ABCC1;ADRA1A;SLC6A3 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;CYP2D6;FDPS GO:0006810| transport ABCC1;SLC6A2 GO:0055085| transmembrane transport SLC6A4;ABCC1;SLC6A2;SLC6A3 42278:[DB00399 DB00295] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00295|Morphine OPRM1;OPRK1;OPRD1;LY96;CYP2D6;CYP2C8;CYP3A4;UGT2B7;UGT1A1;UGT1A8;UGT2B15;UGT2B4;UGT1A3;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process UGT1A1;UGT2B15;CYP2C8;UGT2B7;CYP3A4;UGT1A8;CYP2D6;FDPS GO:0042493| response to drug ABCC1;UGT1A1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6;UGT2B7 42279:[DB00399 DB01393] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01393|Bezafibrate PPARA;PPARD;PPARG;NR1I2;RXRA;RXRB;RXRG;CYP1A1;CYP2C8;CYP3A4;SLCO1B1 common genes common pathways GO:0016032| viral reproduction RXRA;FDPS GO:0006629| lipid metabolic process PPARG;PPARD;PPARA;CYP3A4;FDPS GO:0042908| xenobiotic transport NR1I2;ABCC1 GO:0042493| response to drug ABCC1;CYP1A1;PPARG GO:0008203| cholesterol metabolic process FDPS;RXRA;PPARD GO:0055085| transmembrane transport SLCO1B1;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP1A1;CYP3A4;FDPS;NR1I2 42280:[DB00399 DB00492] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00492|Fosinopril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC15A2;SLC15A1 GO:0006810| transport SLC15A1;ABCC1;SLC15A2 42281:[DB00399 DB00986] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00986|Glycopyrronium CHRM1;CHRM3;CHRM2 common genes common pathways 42282:[DB00399 DB05443] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05443|ADL 10-0101 OPRK1 common genes common pathways 42283:[DB00399 DB05098] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05098|Leptin LEPR common genes common pathways GO:0008203| cholesterol metabolic process LEPR;FDPS 42284:[DB00399 DB00217] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00217|Bethanidine ADRA2A;ADRA2B;ADRA2C;KCNJ1;ADRB1;ADRB2;ADRB3 common genes common pathways 42285:[DB00399 DB09101] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09101|Elvitegravir pol;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;FDPS 42286:[DB00399 DB09344] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09344|Invert sugar GCK;SLC2A2;SLC2A5 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC2A2;SLC2A5 42287:[DB00399 DB01090] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01090|Pentolinium CHRNA10;CHRNA3;CHRNB4 common genes common pathways 42288:[DB00399 DB00361] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00361|Vinorelbine TUBB;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 42289:[DB00399 DB12140] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12140|Dilmapimod TNF;IL1B;IL6 common genes common pathways 42290:[DB00399 DB09262] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09262|Imidafenacin CHRM1;CHRM2;CHRM3;CYP3A4;UGT1A4;ALB;ORM1;ORM2 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42291:[DB00399 DB01088] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01088|Iloprost PTGIR;PTGER1;PDE4A;PDE4B;PDE4C;PDE4D;PLAT;PTGDR2;SLCO2B1;SLCO2A1;SLCO3A1 common genes common pathways GO:0055085| transmembrane transport SLCO2A1;ABCC1;SLCO3A1;SLCO2B1 42292:[DB00399 DB05294] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05294|Vandetanib VEGFA;EGFR;PTK6;TEK;RET;FMO1;FMO3;CYP3A4;ORM1;ALB;ABCC1;ABCG2;SLC22A2 common genes ABCC1 common pathways GO:0099133| ABCC1 GO:0042493| response to drug ABCG2;ABCC1;RET GO:0006691| leukotriene metabolic process ABCC1 GO:0060326| cell chemotaxis ABCC1 GO:0006810| transport ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0009235| cobalamin metabolic process ABCC1 GO:0055085| transmembrane transport SLC22A2;ABCG2;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0034775| glutathione transmembrane transport ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCC1 GO:0099039| ABCC1 GO:0015889| cobalamin transport ABCC1 GO:0006855| drug transmembrane transport SLC22A2;ABCC1;ABCG2 42293:[DB00399 DB04845] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04845|Ixabepilone TUBB3;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42294:[DB00399 DB06413] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06413|Armodafinil SLC6A3;CYP2C19;CYP3A4;CYP3A5;CYP1A2;CYP2B6;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2C9 GO:0008202| steroid metabolic process CYP2C19;CYP3A5;CYP3A4;CYP1A2;FDPS;CYP2B6;CYP2C9 GO:0055085| transmembrane transport SLC6A3;ABCC1 GO:0042493| response to drug CYP1A2;SLC6A3;ABCC1 42295:[DB00399 DB00544] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00544|Fluorouracil TYMS;CYP2C9;CYP1A2;TYMP;DPYD;UPP1;UPP2;CYP2A6;CYP2C8;MTHFR;TYMS;UMPS;PPAT;ALB;SLC22A7;SLC29A1;ABCG2;ABCC3;ABCC4;ABCC5 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP1A2 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCC3 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCC3 GO:0042493| response to drug ABCC1;ABCG2;PPAT;TYMS;MTHFR;CYP1A2;ABCC4 GO:0099133| ABCC5;ABCC4;ABCC3;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCG2;SLC22A7;ABCC5;ABCC4;ABCC3 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP1A2;CYP2A6;CYP2C8 GO:0006810| transport ABCG2;ABCC1;ABCC3;ABCC5 42296:[DB00399 DB00542] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00542|Benazepril ACE;MTHFR;SLC15A1;SLC15A2 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC15A2;SLC15A1 GO:0006810| transport SLC15A2;ABCC1;SLC15A1 GO:0042493| response to drug ABCC1;MTHFR 42297:[DB00399 DB12391] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12391|Sagopilone CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 42298:[DB00399 DB08870] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08870|Brentuximab vedotin TNFRSF8;CYP3A4;ABCB5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042908| xenobiotic transport ABCC1;ABCB5 GO:0006855| drug transmembrane transport ABCC1;ABCB5 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;ABCB5 42299:[DB00399 DB03683] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03683|2-{[Formyl(Hydroxy)Amino]Methyl}-4-Methylpentanoic Acid MMP9 common genes common pathways 42300:[DB00399 DB08873] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08873|Boceprevir CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 42301:[DB00399 DB09119] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09119|Eslicarbazepine acetate P2RX4;CYP2C19;CYP3A4;UGT1A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process UGT1A1;CYP2C19;FDPS;CYP3A4 GO:0042493| response to drug UGT1A1;ABCC1 42302:[DB00399 DB03929] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03929|D-Serine GLRA1;GRIN1;SERPINB3;SLC16A10;SLC6A14 common genes common pathways GO:0006810| transport ABCC1;SLC6A14 GO:0055085| transmembrane transport SLC6A14;SLC16A10;ABCC1 42303:[DB00399 DB00972] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00972|Azelastine HRH1;CYP1A2;CYP3A4;CYP2C19;CYP1A1;CYP3A5;CYP2C9;CYP2C8;CYP2D6;CYP2A6;CYP2B6;CYP2E1;ABCB1 common genes common pathways GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2D6;CYP2C9;CYP2B6;FDPS;CYP1A2;CYP3A4;CYP2A6;CYP3A5;CYP1A1;CYP2E1;CYP2C19;CYP2C8 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;CYP2E1;CYP1A1;ABCB1;CYP1A2 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2 42304:[DB00399 DB12455] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12455|Omadacycline rpsC;rpsG;rpsH;rpsS;rpsN;ALB;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;ABCC1 42305:[DB00399 DB00402] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00402|Eszopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP2C8;CYP2C9;PTGS1 common genes common pathways GO:0042493| response to drug GABRG3;TSPO;ABCC1 GO:0006694| steroid biosynthetic process TSPO;FDPS GO:0008202| steroid metabolic process FDPS;TSPO;CYP2C9;CYP3A4;CYP2C8 GO:0006810| transport GABRA3;GABRA5;GABRB2;GABRB1;GABRA6;GABRA4;ABCC1;GABRD;GABRB3;GABRA1;GABRG2 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;PTGS1 42306:[DB00399 DB01567] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01567|Fludiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0042493| response to drug GABRG3;ABCC1 GO:0006810| transport GABRA3;GABRA5;GABRB2;ABCC1;GABRR2;GABRD;GABRB1;GABRR1;GABRB3;GABRA1;GABRG2 42307:[DB00399 DB00771] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00771|Clidinium CHRM1 common genes common pathways 42308:[DB00399 DB00107] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00107|Oxytocin OXTR;OXT;PREP common genes common pathways GO:0042493| response to drug ABCC1;OXTR 42309:[DB00399 DB00659] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00659|Acamprosate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRM5;SLC36A1 common genes common pathways GO:0042493| response to drug ABCC1;GRIN2A;GABRG3 GO:0055085| transmembrane transport ABCC1;SLC36A1 GO:0006810| transport GABRB3;GABRA1;GRIN2A;GABRG2;GRIN2B;GABRA3;GABRA5;GABRB2;GABRB1;GABRA4;GABRA6;GRIN2C;ABCC1;GABRD 42310:[DB00399 DB09043] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09043|Albiglutide GLP1R common genes common pathways 42311:[DB00399 DB00412] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00412|Rosiglitazone PPARG;ACSL4;PPARA;PPARD;RXRA;RXRB;RXRG;CYP2C8;CYP2C9;PTGS1;CYP1A2;CYP2A6;CYP2D6;CYP3A4;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0042493| response to drug CYP1A2;PPARG;ABCC1 GO:0008203| cholesterol metabolic process RXRA;PPARD;FDPS GO:0055085| transmembrane transport ABCC1;ABCB11;SLCO1B1 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4;CYP2A6;CYP2C8 GO:0006810| transport ABCC1;ABCB11 GO:0016032| viral reproduction RXRA;FDPS GO:0006629| lipid metabolic process PPARG;CYP3A4;PPARA;PPARD;CYP2D6;CYP2C9;FDPS;CYP1A2;ACSL4;PTGS1 42312:[DB00399 DB01608] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01608|Periciazine DRD1;ADRA2A;ADRA1B;AR common genes common pathways GO:0006810| transport AR;ABCC1 GO:0042493| response to drug ABCC1;DRD1 42313:[DB00399 DB06719] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06719|Buserelin LHCGR;GNRHR;CYP19A1 common genes common pathways GO:0006694| steroid biosynthetic process CYP19A1;FDPS 42314:[DB00399 DB14487] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14487|Zinc acetate BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0008203| cholesterol metabolic process FDPS;APOA2;APP;APOA4;APOL1;APOE;APOBR;PON1;APOA1 GO:0006695| cholesterol biosynthetic process APOA1;GGPS1;APOA4;FDPS GO:0060326| cell chemotaxis C5;ABCC1 GO:0042493| response to drug SOD1;TP73;HDAC1;TP53;NME1;APOA1;ABCC1;HDAC4;APOA2;MGMT;MDM2 GO:0008202| steroid metabolic process FDPS;APOL1;APOBR;APOE;APOA1 GO:0006810| transport ABCC1;TTR GO:0055085| transmembrane transport APOA1;ABCC1 GO:0006629| lipid metabolic process APOA1;C3;PON1;APOE;APOBR;APOL1;CLU;FDPS GO:0016032| viral reproduction IDE;SIVA1;TP73;TP53;HDAC1;CFH;MDM2;APOA2;FDPS 42315:[DB00399 DB01119] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01119|Diazoxide KCNJ11;CA1;CA2;ATP1A1;KCNMA1;SLC12A3;GLUL common genes common pathways GO:0042493| response to drug KCNJ11;ABCC1;ATP1A1 GO:0006810| transport ABCC1;SLC12A3 GO:0055085| transmembrane transport SLC12A3;KCNJ11;ABCC1;KCNMA1 42316:[DB00399 DB00026] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00026|Anakinra IL1R1 common genes common pathways 42317:[DB00399 DB04908] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04908|Flibanserin HTR1A;HTR2A;DRD4;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction FDPS;HTR2A GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;HTR2A 42318:[DB00399 DB00842] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00842|Oxazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A43;UGT2B15;UGT2B7;UGT1A9 common genes common pathways GO:0042493| response to drug ABCC1;GABRG3 GO:0008202| steroid metabolic process UGT2B15;UGT2B7;CYP3A4;FDPS GO:0006810| transport GABRA5;GABRA3;GABRB2;GABRB1;GABRA6;GABRR1;GABRA4;GABRR2;ABCC1;GABRD;GABRA1;GABRB3;GABRG2 GO:0006629| lipid metabolic process UGT2B7;CYP3A4;FDPS 42319:[DB00399 DB00440] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00440|Trimethoprim TYMS;DHFR;CYP3A4;CYP2C8;CYP2C9;ABCB1;SLC22A2 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1;TYMS GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C8;CYP2C9;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB1;SLC22A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;SLC22A2 42320:[DB00399 DB00184] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00184|Nicotine CHRNA4;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA5;CHRNA6;CHRNA9;CHRNA10;CHRNB3;CHRNB4;CYP19A1;CHAT;CYP2A6;CYP2E1;CYP2A13;CYP2B6;CYP1A1;CYP1A2;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A4;MAOA;MAOB;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0006855| drug transmembrane transport SLC22A2;SLC22A5;ABCC1;SLC22A3;SLC22A1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;CYP2C9;FDPS;CYP1A2 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP2E1;CYP1A1;CYP3A4;CYP2A6;CYP1A2;FDPS;CYP2C9;CYP2B6;CYP2D6 GO:0006810| transport CHRNB3;ABCC1;CHRNA6 GO:0055085| transmembrane transport SLC22A1;SLC22A4;SLC22A3;ABCC1;SLC22A2;SLC22A5 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0042493| response to drug CYP2E1;CYP1A1;MAOB;ABCC1;CYP1A2 42321:[DB00399 DB06777] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06777|Chenodeoxycholic acid NR1H4;NR1I2;GPBAR1;AKR1C2;CYP27A1;CYP3A4;UGT2B7 common genes common pathways GO:0008202| steroid metabolic process AKR1C2;CYP3A4;NR1I2;FDPS;UGT2B7 GO:0006629| lipid metabolic process AKR1C2;CYP3A4;FDPS;UGT2B7 GO:0042908| xenobiotic transport ABCC1;NR1I2 42322:[DB00399 DB04630] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04630|Aldosterone NR3C2;NR3C1;CYP11B1;CYP11B2;CYP17A1;CYP3A4;ABCB1;SLC22A5;SLCO1A2 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP11B1;CYP17A1;CYP11B2 GO:0008202| steroid metabolic process CYP11B2;CYP17A1;CYP11B1;CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport SLC22A5;ABCC1;SLCO1A2;ABCB1 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4;FDPS GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;SLC22A5 42323:[DB00399 DB01035] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01035|Procainamide SCN5A;DNMT1;KCNH2;CYP2D6;BCHE;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A4;SLC47A1;SLC47A2 common genes common pathways GO:0042493| response to drug BCHE;ABCC1 GO:0055085| transmembrane transport SLC22A3;SLC47A1;KCNH2;SLC22A4;SLC47A2;SLC22A1;SLC22A5;SLC22A2;SCN5A;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2D6 GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0006855| drug transmembrane transport SLC22A2;SLC22A5;ABCC1;SLC47A1;SLC22A3;SLC22A1;SLC47A2 42324:[DB00399 DB05969] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05969|SNS-032 CDK7;VEGFA common genes common pathways 42325:[DB00399 DB00809] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00809|Tropicamide CHRM4;CHRM1;CHRM2;CHRM3 common genes common pathways 42326:[DB00399 DB00648] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00648|Mitotane CYP11B1;FDX1;ESR1;PGR;AR;CYP3A4;SHBG;SERPINA6 common genes common pathways GO:0006694| steroid biosynthetic process FDPS;CYP11B1;FDX1 GO:0008203| cholesterol metabolic process FDX1;FDPS GO:0008202| steroid metabolic process FDX1;CYP11B1;CYP3A4;FDPS GO:0006810| transport ABCC1;AR GO:0006629| lipid metabolic process FDX1;CYP11B1;CYP3A4;FDPS 42327:[DB00399 DB01238] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01238|Aripiprazole HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP2D6;CYP3A4 common genes common pathways GO:0042493| response to drug DRD1;HTR2A;DRD2;ADRA1A;ABCC1;HTR2C;HTR1B;DRD3 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP3A4;FDPS;CYP2D6 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0016032| viral reproduction FDPS;HTR2A 42328:[DB00399 DB02901] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02901|Stanolone HSD17B1;AR;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP11A1;HSD17B1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006694| steroid biosynthetic process CYP19A1;CYP11A1;FDPS;CYP17A1;HSD17B1 GO:0008203| cholesterol metabolic process CYP11A1;FDPS GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP17A1;FDPS;CYP11A1 GO:0006810| transport ABCC1;AR;ABCB1 42329:[DB00399 DB06710] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06710|Methyltestosterone AR;ESR1;CYP19A1;CYP2B6;CYP3A4;ALB;SHBG;SLCO1A2;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;SLCO1A2;SLC22A8 GO:0008202| steroid metabolic process CYP3A4;CYP2B6;FDPS GO:0006810| transport ABCC1;AR GO:0006694| steroid biosynthetic process CYP19A1;FDPS 42330:[DB00399 DB01156] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01156|Bupropion SLC6A3;SLC6A2;CHRNA3;CYP2B6;CYP2D6;CYP2A6;CYP2C8;CYP2C9;CYP2E1;CYP3A4;ORM1;SLC22A2 common genes common pathways GO:0008202| steroid metabolic process CYP2C8;CYP2E1;CYP2A6;CYP3A4;FDPS;CYP2B6;CYP2C9;CYP2D6 GO:0006810| transport SLC6A2;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC6A2;SLC22A2;SLC6A3 GO:0042493| response to drug SLC6A2;ABCC1;CYP2E1;SLC6A3 GO:0006855| drug transmembrane transport SLC22A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9;CYP2D6 42331:[DB00399 DB00496] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00496|Darifenacin CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 42332:[DB00399 DB04070] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04070|6-Deoxyerythronolide B CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42333:[DB00399 DB00807] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00807|Proparacaine SCN10A common genes common pathways GO:0055085| transmembrane transport ABCC1;SCN10A 42334:[DB00399 DB00318] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00318|Codeine OPRM1;OPRK1;OPRD1;CYP2D6;CYP3A4;CYP3A5;CYP3A7;UGT2B7;UGT2B4;UGT1A1;SLC22A1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4;UGT2B7 GO:0006855| drug transmembrane transport SLC22A1;ABCC1 GO:0042493| response to drug ABCC1;UGT1A1 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;UGT1A1;CYP3A5;CYP3A7;UGT2B7 GO:0055085| transmembrane transport ABCC1;SLC22A1 42335:[DB00399 DB00443] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00443|Betamethasone NR3C1;CYP3A4;CYP19A1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 42336:[DB00399 DB01217] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01217|Anastrozole CYP19A1;CYP19A1;CYP1A2;CYP2C9;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2C9 GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2C9;CYP3A4 42337:[DB00399 DB06791] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06791|Lanreotide SSTR2;SSTR5;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 42338:[DB00399 DB01622] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01622|Thioproperazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0042493| response to drug HTR2A;DRD1;ADRA1A;DRD2;ABCC1 GO:0016032| viral reproduction HTR2A;FDPS 42339:[DB00399 DB09286] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09286|Pipamperone DRD2;HTR2A;ADRA1A;ADRA1B;ADRA1D;DRD4;DRD1;DRD3;HTR2B;ADRA2A common genes common pathways GO:0042493| response to drug HTR2B;ABCC1;DRD2;ADRA1A;DRD1;HTR2A;DRD3 GO:0016032| viral reproduction HTR2A;FDPS 42340:[DB00399 DB01062] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01062|Oxybutynin CHRM3;CHRM2;CHRM1;CYP3A4;CYP2C8;CYP2D6;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP2C8;CYP3A5 42341:[DB00399 DB00780] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00780|Phenelzine MAOA;MAOB;AOC3;ABAT;GPT;GPT2;GAD65;MAOA;CYP2E1;MAOB;CYP2C19;CYP2C8;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4;CYP3A7;CYP2E1;CYP3A5;CYP2C19;CYP2C8 GO:0042493| response to drug ABAT;MAOB;CYP2E1;ABCC1 42342:[DB00399 DB05767] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05767|Andrographolide TNF;IL1B;IL6;NFKB2;NFKB1 common genes common pathways 42343:[DB00399 DB06820] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06820|Sulconazole CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2 GO:0042493| response to drug ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2 42344:[DB00399 DB01320] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01320|Fosphenytoin SCN5A;CYP2C9;CYP2C19;CYP3A4;CYP2B6;CYP1A2;UGT1A6;UGT1A9;CYP2D6;ALB common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;FDPS GO:0042493| response to drug ABCC1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP3A4;CYP2C19 GO:0055085| transmembrane transport SCN5A;ABCC1 42345:[DB00399 DB00933] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00933|Mesoridazine HTR2A;DRD2;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6 GO:0016032| viral reproduction HTR2A;FDPS GO:0042493| response to drug HTR2A;DRD2;ABCC1 GO:0008202| steroid metabolic process CYP2D6;FDPS 42346:[DB00399 DB00804] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00804|Dicyclomine CHRM1;CHRM2;CYP1A1 common genes common pathways GO:0042493| response to drug CYP1A1;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP1A1 42347:[DB00399 DB01388] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01388|Mibefradil CACNA1G;CACNA1H;CACNA1C;CACNA1D;CACNA1F;CACNA1I;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;CYP1A2;CYP2D6;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP1A1;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP11B2;CYP11B1;CYP3A4;CYP2D6;CYP1A2;FDPS GO:0008202| steroid metabolic process CYP11B1;CYP3A7;CYP1A1;CYP3A5;CYP11B2;CYP1A2;FDPS;CYP2D6;CYP3A4 GO:0006810| transport CACNB3;ABCC1;CACNB1;CACNB4;CACNA1I;ABCB1 GO:0055085| transmembrane transport CACNA1D;CACNA1C;CACNA1S;ABCC1;CACNA1H;CACNA1G;CACNA1I;ABCB1;CACNA1F GO:0042493| response to drug ABCB1;CYP1A2;ABCC1;CYP1A1 GO:0006694| steroid biosynthetic process CYP11B1;CYP11B2;FDPS 42348:[DB00399 DB00106] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00106|Abarelix GNRHR common genes common pathways 42349:[DB00399 DB01115] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01115|Nifedipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CALM1;KCNA1;CACNA1H;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2A6;CYP2C8;CYP2D6;CYP2E1;CYP1A1;CYP2B6;ABCC3;ABCB1;ABCC2;SLCO1B1;ABCB11 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC2;ABCC3;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport NR1I2;ABCC3;ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS;CYP1A2 GO:0055085| transmembrane transport ABCC2;ABCB1;KCNA1;ABCC3;CACNA1S;ABCC1;CACNA1H;CALM1;SLCO1B1;ABCB11;CACNA1D;CACNA1C GO:0008202| steroid metabolic process CYP2A6;CYP3A4;CYP1A2;FDPS;NR1I2;CYP2B6;CYP2D6;CYP2C8;CYP3A7;CYP2E1;CYP1A1;CYP3A5 GO:0006810| transport ABCC3;ABCB1;ABCC2;ABCB11;ABCC1 GO:0099133| ABCC1;ABCC3;ABCC2 GO:0042493| response to drug CYP1A1;CYP2E1;ABCC1;CYP1A2;ABCC2;ABCB1 42350:[DB00399 DB14062] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14062|Concanamycin A ABCB1 common genes common pathways GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 42351:[DB00399 DB09118] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09118|Stiripentol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;LDHA;LDHB;CYP2C19;CYP2D6;CYP3A4;CYP1A2;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 GO:0042493| response to drug GABRG3;CYP1A2;LDHA;ABCC1 GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRA3;GABRA5;GABRB2;GABRB1;GABRA6;GABRA4;ABCC1;GABRD GO:0008202| steroid metabolic process CYP2C19;CYP2C9;CYP2D6;CYP1A2;FDPS;CYP3A4 42352:[DB00399 DB11943] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11943|Delafloxacin parC;gyrA;UGT1A1;UGT1A3;UGT2B15;CYP2E1;CYP2C9;CYP3A4;ALB;ABCB5;ABCG2 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2C9;FDPS GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB5 GO:0042908| xenobiotic transport ABCB5;ABCC1;ABCG2 GO:0042493| response to drug ABCC1;UGT1A1;ABCG2;CYP2E1 GO:0055085| transmembrane transport ABCB5;ABCC1;ABCG2 GO:0006810| transport ABCG2;ABCC1 GO:0008202| steroid metabolic process FDPS;CYP2C9;CYP3A4;CYP2E1;UGT1A1;UGT2B15 42353:[DB00399 DB01558] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01558|Bromazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;CYP3A4;CYP1A2;CYP2C19;CYP2E1 common genes common pathways GO:0042493| response to drug GABRG3;CYP1A2;ABCC1;CYP2E1 GO:0006810| transport GABRB2;GABRA3;GABRA5;GABRD;ABCC1;GABRR2;GABRR1;GABRA6;GABRA4;GABRB1;GABRB3;GABRA1;GABRG2 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP2C19;CYP2E1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP3A4 42354:[DB00399 DB08932] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08932|Macitentan EDNRA;EDNRB;CYP3A4;CYP2C19;ALB common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C19 GO:0006629| lipid metabolic process CYP3A4;FDPS 42355:[DB00399 DB13975] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13975|Cimicifuga racemosa CYP3A4;CYP1A2;CYP2C9;CYP2D6 common genes common pathways GO:0042493| response to drug ABCC1;CYP1A2 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2C9;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;CYP2C9;CYP2D6;CYP1A2;FDPS 42356:[DB00399 DB00042] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00042|Botulinum Toxin Type B VAMP2;VAMP1;SYT2 common genes common pathways 42357:[DB00399 DB00254] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00254|Doxycycline rpsI;rpsD;PADI4;B2M;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport SLC22A8;SLC22A6;SLC22A11;ABCC1 GO:0042493| response to drug ABCC1;B2M 42358:[DB00399 DB00938] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00938|Salmeterol ADRB2;ADRB1;ADRB3;CYP3A4;CYP3A5;CYP3A7;CYP2C8 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4;CYP3A5;CYP3A7;CYP2C8 42359:[DB00399 DB13955] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13955|Estradiol dienanthate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0055085| transmembrane transport SLC22A3;SLCO1B3;SLCO1C1;SLC22A1;ABCB1;SLCO2B1;SLC22A2;ABCC10;SLCO1B1;SLC22A8;SLCO4A1;ABCC1;ABCG2;SLCO1A2;SLC22A11 GO:0008202| steroid metabolic process CYP1B1;CYP3A4;NR1I2;CYP2C9;CYP1A2;FDPS;UGT1A1;CYP2C8;CYP2C19;CYP1A1;CYP3A5;CYP3A7 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0042493| response to drug CYP1A1;BECN1;UGT1A1;ABCC1;ABCG2;CYP1A2;ABCB1 GO:0099133| ABCC1;ABCC10 GO:0006694| steroid biosynthetic process FDPS;HSD17B2 GO:0006855| drug transmembrane transport SLC22A3;SLC22A1;ABCB1;SLC22A2;ABCC1;ABCG2 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1;NR1I2 GO:0016032| viral reproduction FDPS;BECN1 GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2C9;CYP3A4;HSD17B2 42360:[DB00399 DB00546] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00546|Adinazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2C19;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP3A4 GO:0006810| transport GABRB3;GABRA1;GABRG2;GABRA3;GABRA5;GABRB2;GABRB1;GABRR1;GABRR2;ABCC1;GABRD GO:0042493| response to drug ABCC1;GABRG3 GO:0006629| lipid metabolic process CYP3A4;FDPS 42361:[DB00399 DB14700] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14700|Damoctocog alfa pegol F8 common genes common pathways 42362:[DB00399 DB09381] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09381|Estrogens, esterified CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process FDPS;CYP3A4 42363:[DB00399 DB00418] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00418|Secobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2C9;CYP2C8;CYP1A2;CYP2C19 common genes common pathways GO:0042493| response to drug CYP1A2;GRIN2A;ABCC1 GO:0055085| transmembrane transport ABCC1;GRIK2 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2C9;CYP2C8;CYP2C19 GO:0006810| transport GRIN2C;ABCC1;GRIK2;GABRA6;GABRA4;GABRA5;GABRA3;GRIN2B;GRIN2A;GABRA1 GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP1A2 42364:[DB00399 DB09095] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09095|Difluocortolone ANXA3;NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 42365:[DB00399 DB13345] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13345|Dihydroergocristine HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;ADRB1;ADRB2;ADRB3;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD1;DRD5;DRD2;DRD3;DRD4;CYP3A4;ABCB11 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB11 GO:0006810| transport ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0042493| response to drug HTR2A;DRD1;DRD2;ADRA1A;ABCC1;HTR2B;HTR2C;DRD3;HTR1B GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process FDPS;CYP3A4 42366:[DB00399 DB06623] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06623|Flupirtine ADRA2A common genes common pathways 42367:[DB00399 DB00428] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00428|Streptozocin SLC2A2;MGEA5;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;ABCC1;CYP2E1;CYP1A1 GO:0008202| steroid metabolic process CYP1A1;CYP2E1;FDPS;CYP1A2 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCB1;SLC2A2;ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 42368:[DB00399 DB09244] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09244|Pirlindole MAOA;HTR1A;ADRA2A;MAOA common genes common pathways 42369:[DB00399 DB00387] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00387|Procyclidine CHRM1;CHRM2;CHRM4;CHRM3 common genes common pathways 42370:[DB00399 DB11718] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11718|Encorafenib BRAF;CCND1;CYP3A4;CYP2C19;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS GO:0008202| steroid metabolic process CYP2C19;FDPS;CYP2D6;CYP3A4 GO:0042493| response to drug CCND1;ABCC1 42371:[DB00399 DB05133] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05133|VP025 IL1B common genes common pathways 42372:[DB00399 DB00956] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00956|Hydrocodone OPRM1;OPRD1;CYP2D6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 42373:[DB00399 DB01235] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01235|Levodopa DRD1;DRD5;DRD2;DRD3;DRD4;DDC;SLC15A1;SLC16A10;SLC7A5;SLC7A8 common genes common pathways GO:0042493| response to drug ABCC1;DRD1;DRD2;DRD3 GO:0055085| transmembrane transport SLC15A1;SLC16A10;ABCC1 GO:0006810| transport SLC15A1;SLC7A5;SLC7A8;ABCC1 42374:[DB00399 DB00590] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00590|Doxazosin ADRA1A;ADRA1B;ADRA1D;KCNH2;KCNH6;KCNH7;CYP2C19;CYP2D6;CYP3A4;ORM1;ABCB1;SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1;SLC22A1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0055085| transmembrane transport ABCC1;KCNH7;KCNH2;SLC22A1;ABCB1;KCNH6 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6;CYP2C19 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1;ADRA1A 42375:[DB00399 DB01278] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01278|Pramlintide CALCR;RAMP1;RAMP2;RAMP3 common genes common pathways 42376:[DB00399 DB00333] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00333|Methadone OPRM1;GRIN3A;CHRNA10;OPRD1;HTR3A;LY96;ORM2;CYP3A4;CYP2C19;CYP3A5;CYP3A7;CYP2D6;CYP2B6;CYP2C8;CYP19A1;CYP1A2;CYP2C18;CYP2C9;ABCB1 common genes common pathways GO:0006810| transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C8;CYP2C19;CYP3A5;CYP3A7;CYP3A4;CYP2C9;CYP2B6;CYP2D6;CYP1A2;FDPS GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0042493| response to drug CYP1A2;ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP1A2;CYP3A4 42377:[DB00399 DB01348] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01348|Spirapril ACE;SLC15A1;SLC15A2 common genes common pathways GO:0006810| transport SLC15A2;ABCC1;SLC15A1 GO:0055085| transmembrane transport ABCC1;SLC15A2;SLC15A1 42378:[DB00399 DB00961] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00961|Mepivacaine SCN10A common genes common pathways GO:0055085| transmembrane transport SCN10A;ABCC1 42379:[DB00399 DB09054] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09054|Idelalisib AOX1;CYP2C8;CYP2C19;CYP2B6;CYP3A4;CYP3A5;CYP3A43;CYP3A7;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0042493| response to drug ABCB1;ABCG2;ABCC1 GO:0008202| steroid metabolic process CYP3A7;CYP3A5;CYP2C8;CYP2C19;FDPS;CYP2B6;CYP3A4 GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCB1;SLCO1B3;ABCG2;ABCC1;SLCO1B1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1;ABCG2 42380:[DB00399 DB06825] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06825|Triptorelin GNRHR common genes common pathways 42381:[DB00399 DB01565] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01565|Dihydromorphine OPRM1;OPRD1;OPRK1;TRIM13;POMC common genes common pathways 42382:[DB00399 DB14575] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14575|Eslicarbazepine P2RX4;UGT1A1;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0042493| response to drug UGT1A1;ABCC1 GO:0008202| steroid metabolic process CYP2C19;UGT1A1;CYP3A4;FDPS 42383:[DB00399 DB09270] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09270|Ubidecarenone NDUFV3;SDHA;HMGCR;LDLR;VLDLR;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0016126| sterol biosynthetic process HMGCR;FDPS GO:0006629| lipid metabolic process FDPS;LDLR;HMGCR;VLDLR GO:0016032| viral reproduction FDPS;LDLR GO:0008202| steroid metabolic process FDPS;VLDLR;HMGCR;LDLR GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0045540| regulation of cholesterol biosynthetic process FDPS;GGPS1;HMGCR GO:0008299| isoprenoid biosynthetic process FDPS;GGPS1;HMGCR GO:0008203| cholesterol metabolic process FDPS;VLDLR;HMGCR;LDLR GO:0006695| cholesterol biosynthetic process HMGCR;GGPS1;FDPS GO:0006694| steroid biosynthetic process HMGCR;FDPS GO:0042493| response to drug ABCB1;ABCC1 42384:[DB00399 DB05675] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05675|EP-2104R FGA common genes common pathways 42385:[DB00399 DB00327] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00327|Hydromorphone OPRM1;OPRD1;OPRK1;CYP3A4;CYP2C9;PTGS1;UGT1A9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS;CYP3A4;PTGS1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C9 42386:[DB00399 DB00073] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00073|Rituximab MS4A1 common genes common pathways 42387:[DB00399 DB06494] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06494|Sufugolix GNRHR common genes common pathways 42388:[DB00399 DB05239] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05239|Cobimetinib MAP2K1;CYP3A4;ABCB1;SLCO1B1;SLCO1B3;ABCG2 common genes common pathways GO:0006810| transport ABCC1;ABCG2;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport SLCO1B1;ABCG2;ABCC1;SLCO1B3;ABCB1 GO:0042493| response to drug ABCG2;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCG2;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 42389:[DB00399 DB02703] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB02703|Fusidic Acid fusA;cat;CYP2D6;CYP3A4;UGT1A1;ABCB11;ABCC2;ABCG2;SLCO1B1 common genes common pathways GO:0006855| drug transmembrane transport ABCC2;ABCG2;ABCC1 GO:0042908| xenobiotic transport ABCG2;ABCC1 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0055085| transmembrane transport ABCC2;ABCC1;ABCG2;ABCB11;SLCO1B1 GO:0006810| transport ABCC2;ABCC1;ABCG2;ABCB11 GO:0008202| steroid metabolic process UGT1A1;CYP3A4;CYP2D6;FDPS GO:0042493| response to drug ABCG2;UGT1A1;ABCC1;ABCC2 GO:0099133| ABCC1;ABCC2 42390:[DB00399 DB00518] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00518|Albendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1;CYP1A2;CYP2C19;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP2C19;CYP1A1;CYP3A4;FDPS;CYP1A2 GO:0006810| transport ABCB1;ABCC1 GO:0042493| response to drug CYP1A2;ABCB1;CYP1A1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP3A4 42391:[DB00399 DB13835] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13835|Caroverine CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42392:[DB00399 DB00268] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00268|Ropinirole DRD3;DRD2;DRD4;HTR1A;HTR1D;HTR2B;DRD1;DRD5;HTR1B;HTR2A;HTR2C;ADRA2A;ADRA2B;ADRA2C;CYP1A2;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2D6;CYP3A4 GO:0042493| response to drug HTR1B;DRD3;HTR2C;CYP1A2;HTR2B;ABCC1;DRD2;DRD1;HTR2A GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6 42393:[DB00399 DB01196] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01196|Estramustine MAP2;MAP1A;ESR1;ESR2;CYP3A4;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 42394:[DB00399 DB11362] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11362|Selexipag PTGIR;CES1;CYP2C8;CYP3A4;SLCO1B1;SLCO1B3;ABCB1 common genes common pathways GO:0006695| cholesterol biosynthetic process CES1;FDPS;GGPS1 GO:0042493| response to drug ABCC1;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C8 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLCO1B1;ABCB1;SLCO1B3 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 42395:[DB00399 DB01039] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01039|Fenofibrate PPARA;PPARG;PPARD;NR1I2;CYP2C8;CYP2C9;CYP3A4;UGT1A1;ABCB11 common genes common pathways GO:0042908| xenobiotic transport ABCC1;NR1I2 GO:0006629| lipid metabolic process PPARD;PPARA;CYP3A4;PPARG;FDPS;CYP2C9 GO:0055085| transmembrane transport ABCB11;ABCC1 GO:0006810| transport ABCC1;ABCB11 GO:0008202| steroid metabolic process CYP2C8;UGT1A1;CYP3A4;FDPS;CYP2C9;NR1I2 GO:0042493| response to drug ABCC1;UGT1A1;PPARG GO:0008203| cholesterol metabolic process FDPS;PPARD 42396:[DB00399 DB06263] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06263|Amrubicin TOP2A;POR;CBR1;ABCB5 common genes common pathways GO:0042493| response to drug ABCC1;POR GO:0055085| transmembrane transport ABCC1;ABCB5 GO:0006855| drug transmembrane transport ABCC1;ABCB5 GO:0042908| xenobiotic transport ABCB5;ABCC1 42397:[DB00399 DB00186] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00186|Lorazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;UGT2B15;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug TSPO;GABRG3;ABCC1 GO:0006694| steroid biosynthetic process TSPO;FDPS GO:0008202| steroid metabolic process UGT2B15;CYP3A4;FDPS;TSPO GO:0006810| transport GABRA1;GABRB3;GABRG2;GABRA5;GABRA3;GABRB2;GABRB1;GABRA4;GABRA6;ABCC1;GABRD 42398:[DB00399 DB05710] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05710|Gantacurium Chloride CHRNA3 common genes common pathways 42399:[DB00399 DB00426] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00426|Famciclovir AOX1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42400:[DB00399 DB06809] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06809|Plerixafor CXCR4 common genes common pathways GO:0016032| viral reproduction CXCR4;FDPS 42401:[DB00399 DB00753] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00753|Isoflurane GABRA1;ATP2C1;GLRA1;GRIA1;KCNA1;CALM1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNB2;CYP2E1;CYP2B6;MT-ND1;ALB common genes common pathways GO:0042493| response to drug GABRG3;MT-ND1;CYP2E1;ABCC1 GO:0008202| steroid metabolic process CYP2B6;FDPS;CYP2E1 GO:0006810| transport GABRB2;GABRA3;GABRA5;GABRD;ABCC1;GABRA6;GABRA4;GABRB1;GABRB3;GABRA1;GABRG2 GO:0055085| transmembrane transport CALM1;ABCC1;KCNA1 42402:[DB00399 DB12161] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB12161|Deutetrabenazine SLC18A2;CBR1;CBR3;CYP2D6;CYP1A2;CYP3A5;CYP3A4 common genes common pathways GO:0055085| transmembrane transport ABCC1;SLC18A2 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS;CYP1A2;CYP3A5 GO:0042493| response to drug CYP1A2;ABCC1 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2D6;CYP3A4 42403:[DB00399 DB08909] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08909|Glycerol phenylbutyrate PNLIP;CYP3A4;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;PNLIP;FDPS;CYP2D6 42404:[DB00399 DB01201] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01201|Rifapentine rpoC;CYP2C9;CYP3A4;CYP2C8;CYP2D6;CYP3A43;CYP2C19;CYP2B6 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2B6;CYP2C9;CYP2D6;CYP2C19;CYP2C8 GO:0006629| lipid metabolic process CYP2D6;CYP2C9;FDPS;CYP3A4 42405:[DB00399 DB00688] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00688|Mycophenolate mofetil IMPDH1;IMPDH2;UGT1A1;UGT1A7;UGT1A6;UGT1A9;UGT2B7;UGT1A8;UGT1A10;CES1;CES2;CYP3A4;CYP3A5;CYP2C8;ALB;SLCO1B1;SLCO1B3;ABCC2;ABCG2;ABCB1 common genes common pathways GO:0099133| ABCC1;ABCC2 GO:0042493| response to drug ABCB1;ABCC2;UGT1A1;ABCC1;ABCG2 GO:0006695| cholesterol biosynthetic process FDPS;GGPS1;CES1 GO:0055085| transmembrane transport ABCC2;ABCB1;SLCO1B3;ABCC1;ABCG2;SLCO1B1 GO:0008202| steroid metabolic process UGT1A8;FDPS;CYP3A4;CYP3A5;UGT2B7;UGT1A1;CYP2C8 GO:0006810| transport ABCC2;ABCB1;ABCC1;ABCG2 GO:0006629| lipid metabolic process FDPS;CYP3A4;UGT2B7 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCC2;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCG2;ABCB1 42406:[DB00399 DB00747] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00747|Scopolamine CHRM1;SI;CHRM2;CHRM3;CHRM4;CHRM5;CHRNA4;CHRNB2;ABCB1 common genes common pathways GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC1 42407:[DB00399 DB01117] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01117|Atovaquone MT-CYB;DHODH;CYP2C9;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9;CYP3A4 GO:0042493| response to drug MT-CYB;DHODH;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C9 42408:[DB00399 DB04855] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04855|Dronedarone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;KCNH2;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;SCN1A;KCNK2;CYP3A4;CYP2D6;ALB;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP2D6;FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042493| response to drug ADRA1A;ABCC1;ABCB1 GO:0055085| transmembrane transport KCNH2;ABCB1;CACNA1F;CACNA1S;ABCC1;SCN1A;CACNA1D;CACNA1C GO:0006810| transport CACNB4;CACNB1;ABCC1;CACNB3;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2D6 42409:[DB00399 DB00343] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00343|Diltiazem CACNG1;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2D6;CYP2C8;ABCB1 common genes common pathways GO:0006810| transport ABCB1;ABCC1;CACNG1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP3A5;CYP3A7;CYP3A4;CYP2D6;FDPS GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP2D6;FDPS 42410:[DB00399 DB04065] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04065|N-Cyclopentyl-N-Cyclobutylformamide ADH1A common genes common pathways 42411:[DB00399 DB00844] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00844|Nalbuphine OPRK1;OPRM1;OPRD1 common genes common pathways 42412:[DB00399 DB00624] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00624|Testosterone AR;ESR1;NR3C2;CYP3A5;CYP19A1;CYP11A1;MAOA;CYP3A7;CYP3A4;CYP1A1;CYP1B1;CYP2A13;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP3A43;ALB;SHBG;SLCO1A2;SLC22A8;SLC22A7;ABCB1;SLC10A1;SLC22A3;SLC22A4;ABCG2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A3;ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0016032| viral reproduction SLC10A1;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP11A1;CYP2C9 GO:0055085| transmembrane transport SLC22A8;SLC22A7;ABCC1;ABCG2;SLCO1A2;SLC10A1;SLC22A3;ABCB1;SLC22A4 GO:0008202| steroid metabolic process CYP2C9;CYP2B6;CYP11A1;FDPS;CYP1B1;CYP3A4;CYP1A1;CYP3A5;CYP3A7;CYP2C8;CYP2C19 GO:0006810| transport SLC10A1;ABCB1;AR;ABCC1;ABCG2 GO:0006694| steroid biosynthetic process CYP11A1;FDPS;CYP19A1 GO:0042493| response to drug CYP1A1;ABCG2;ABCC1;ABCB1 GO:0008203| cholesterol metabolic process FDPS;CYP11A1 42413:[DB00399 DB00934] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00934|Maprotiline SLC6A2;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;HTR2A;HTR2C;HTR7;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP1A2;ORM1 common genes common pathways GO:0006810| transport ABCC1;SLC6A2 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP1A2 GO:0055085| transmembrane transport SLC6A2;ABCC1 GO:0042493| response to drug HTR2A;DRD2;ADRA1A;ABCC1;SLC6A2;CYP1A2;HTR2C GO:0006629| lipid metabolic process FDPS;CYP1A2;CYP2D6 GO:0016032| viral reproduction FDPS;HTR2A 42414:[DB00399 DB11386] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11386|Chlorobutanol KCNH2 common genes common pathways GO:0055085| transmembrane transport KCNH2;ABCC1 42415:[DB00399 DB13951] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13951|Stanolone acetate AR;HSD17B1;ESR1;NR3C2;CYP11A1;CYP17A1;CYP19A1;SHBG;ABCB1 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP11A1;HSD17B1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0008203| cholesterol metabolic process CYP11A1;FDPS GO:0042493| response to drug ABCC1;ABCB1 GO:0006694| steroid biosynthetic process CYP17A1;HSD17B1;CYP19A1;CYP11A1;FDPS GO:0008202| steroid metabolic process CYP17A1;CYP11A1;FDPS GO:0006810| transport ABCB1;AR;ABCC1 GO:0055085| transmembrane transport ABCC1;ABCB1 42416:[DB00399 DB14003] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14003|alpha-Tocopherol acetate CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process VLDLR;LDLR;TTPA;APOBR;CYP3A4;FDPS GO:0016032| viral reproduction FDPS;LDLR;SCARB1 GO:0006810| transport TTPA;ABCC1;ABCB1 GO:0008202| steroid metabolic process FDPS;CYP3A4;APOBR;LDLR;VLDLR GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0045540| regulation of cholesterol biosynthetic process SEC14L2;GGPS1;FDPS GO:0008203| cholesterol metabolic process FDPS;VLDLR;LDLR;APOBR GO:0042493| response to drug ABCC1;ABCB1 GO:0006691| leukotriene metabolic process CYP4F2;ABCC1 42417:[DB00399 DB09128] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09128|Brexpiprazole HTR1A;DRD2;HTR2A;ADRA2C;ADRA1B;CYP2D6;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP3A4 GO:0042493| response to drug HTR2A;DRD2;ABCC1 GO:0016032| viral reproduction FDPS;HTR2A GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 42418:[DB00399 DB09202] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09202|Cirazoline ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0042493| response to drug ADRA1A;ABCC1 42419:[DB00399 DB11642] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11642|Pitolisant HRH3;KCNH2;CYP3A4;CYP2D6;CYP1A2;CYP2B6;SLC22A1 common genes common pathways GO:0055085| transmembrane transport SLC22A1;KCNH2;ABCC1 GO:0008202| steroid metabolic process CYP2B6;CYP2D6;CYP1A2;FDPS;CYP3A4 GO:0042493| response to drug CYP1A2;ABCC1 GO:0006855| drug transmembrane transport SLC22A1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6 42420:[DB00399 DB07177] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB07177|(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID PTGR1;PTGR2 common genes common pathways GO:0006691| leukotriene metabolic process PTGR1;ABCC1 42421:[DB00399 DB03793] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB03793|Benzoic Acid DAO;HRSP12;RAB9A;cpo;repA;PRDX5;SLC15A1;SLCO2B1;SLC22A8;SLC16A1 common genes common pathways GO:0055085| transmembrane transport SLC16A1;SLC15A1;ABCC1;SLC22A8;SLCO2B1 GO:0006810| transport SLC15A1;ABCC1 GO:0006629| lipid metabolic process SLC16A1;FDPS 42422:[DB00399 DB06273] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06273|Tocilizumab IL6R;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process CYP3A4;FDPS 42423:[DB00399 DB00603] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00603|Medroxyprogesterone acetate PGR;ESR1;CYP3A4;CYP2C8;HSD3B2;CYP2C9 common genes common pathways GO:0006694| steroid biosynthetic process FDPS;HSD3B2 GO:0008202| steroid metabolic process CYP2C8;FDPS;CYP2C9;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2C9 42424:[DB00399 DB06480] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06480|Prucalopride HTR4;CYP3A4;ALB;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0055085| transmembrane transport ABCC1;ABCB1 42425:[DB00399 DB13293] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13293|Ipecac CYP2D6;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP3A4 GO:0008202| steroid metabolic process CYP3A4;CYP2D6;FDPS 42426:[DB00399 DB00472] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00472|Fluoxetine SLC6A4;KCNH2;HTR2C;CKS1B;CHRNA2;CHRNA3;CHRNB4;CYP2C19;CYP2D6;CYP2C9;CYP2B;CYP1A2;CYP3A4;CYP2B6;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2;CYP2D6;CYP2C9 GO:0055085| transmembrane transport KCNH2;SLC6A4;ABCB1;ABCC1 GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP3A5;CYP3A4;CYP1A2;FDPS;CYP2B6;CYP2C9;CYP2D6 GO:0042493| response to drug ABCC1;ABCB1;SLC6A4;HTR2C;CYP1A2 42427:[DB00399 DB00881] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00881|Quinapril ACE;SLC15A1;SLC15A2;SLC22A8 common genes common pathways GO:0006810| transport SLC15A1;ABCC1;SLC15A2 GO:0055085| transmembrane transport SLC15A1;ABCC1;SLC22A8;SLC15A2 42428:[DB00399 DB00170] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00170|Menadione GGCX;VKORC1;VKORC1L1;F2;F7;F9;F10;PROC;PROS1;PROZ;NQO2;NQO1;BGLAP;XDH;AOX1;CYP2E1;MTHFR;CYP1A1;CYP1A2;CYP2A6 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0008202| steroid metabolic process CYP2E1;CYP1A1;CYP1A2;FDPS;CYP2A6 GO:0042493| response to drug ABCC1;CYP1A1;CYP2E1;MTHFR;CYP1A2 42429:[DB00399 DB06403] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06403|Ambrisentan EDNRA;EDNRB;CYP3A4;CYP2C19;UGT1A9;UGT2B7;UGT1A3;CYP3A5;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;UGT2B7 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0042493| response to drug ABCB1;ABCC1 GO:0055085| transmembrane transport SLCO1B1;ABCC1;SLCO1B3;ABCB1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C19;CYP3A5;UGT2B7 GO:0006810| transport ABCC1;ABCB1 42430:[DB00399 DB01339] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01339|Vecuronium CHRNA2;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCC1 42431:[DB00399 DB13857] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13857|Demegestone PGR;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006629| lipid metabolic process FDPS;CYP3A4 42432:[DB00399 DB05939] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05939|MK-0354 GPER1 common genes common pathways 42433:[DB00399 DB06168] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06168|Canakinumab IL1B common genes common pathways 42434:[DB00399 DB00952] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00952|Naratriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA common genes common pathways GO:0042493| response to drug HTR1B;ABCC1 42435:[DB00399 DB00909] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00909|Zonisamide SCN1A;SCN2A;SCN3A;SCN4A;SCN5A;SCN9A;SCN11A;SCN1B;SCN2B;SCN3B;SCN4B;CACNA1G;CACNA1H;CACNA1I;CA1;CA2;CA3;CA4;CA5A;CA5B;CA6;CA7;CA8;CA9;CA10;CA11;CA12;CA13;CA14;MAOB;MAOA;CYP3A4;AOX1;CYP2C19;UGT1A1;CYP3A5 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport CACNA1G;SCN2A;CACNA1I;SCN11A;SCN3A;SCN9A;SCN1A;ABCC1;SCN4A;CACNA1H;SCN5A GO:0006810| transport ABCC1;CACNA1I GO:0008202| steroid metabolic process CYP3A4;FDPS;UGT1A1;CYP2C19;CYP3A5 GO:0042493| response to drug SCN11A;UGT1A1;ABCC1;CA9;MAOB 42436:[DB00399 DB00222] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00222|Glimepiride KCNJ11;KCNJ1;ABCC8;CYP2C9;ABCB11 common genes common pathways GO:0099133| ABCC8;ABCC1 GO:0042493| response to drug ABCC8;KCNJ11;ABCC1 GO:0055085| transmembrane transport ABCC8;KCNJ11;ABCC1;ABCB11 GO:0006810| transport ABCB11;ABCC1 GO:0008202| steroid metabolic process CYP2C9;FDPS GO:0006629| lipid metabolic process CYP2C9;FDPS 42437:[DB00399 DB00721] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00721|Procaine SCN10A;GRIN3A;HTR3A;SLC6A3;CHRNA2;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;MAOA;MAOB;BCHE common genes common pathways GO:0045332| phospholipid translocation ABCC1;KCNN4 GO:0042493| response to drug BCHE;SLC6A3;MAOB;ABCC1 GO:0055085| transmembrane transport SLC6A3;KCNMA1;ABCC1;SCN10A 42438:[DB00399 DB00273] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00273|Topiramate GABRA1;SCN1A;GRIK1;CA2;CA4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CA1;CA3;CYP2C19;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug ABCC1;GABRG3 GO:0055085| transmembrane transport ABCC1;GRIK1;SCN1A GO:0006810| transport GABRA3;GABRA5;GABRB2;ABCC1;GABRD;GABRB1;GABRA6;GABRA4;GRIK1;GABRA1;GABRB3;GABRG2 GO:0008202| steroid metabolic process CYP2C19;CYP3A4;FDPS 42439:[DB00399 DB14507] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB14507|Lithium citrate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006810| transport GRIA3;ABCC1 42440:[DB00399 DB01195] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01195|Flecainide SCN5A;SCN4A;KCNH2;CYP2D6;CYP2C9 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP2D6;CYP2C9 GO:0055085| transmembrane transport ABCC1;SCN4A;SCN5A;KCNH2 GO:0006629| lipid metabolic process FDPS;CYP2D6;CYP2C9 42441:[DB00399 DB11071] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11071|Phenyl salicylate PTGS1;PTGS2 common genes common pathways GO:0006629| lipid metabolic process PTGS2;PTGS1;FDPS GO:0042493| response to drug PTGS2;ABCC1 42442:[DB00399 DB05232] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05232|Tetrodotoxin SCN1A;SCN2A;SCN3A;SCN8A common genes common pathways GO:0055085| transmembrane transport SCN3A;SCN1A;ABCC1;SCN2A;SCN8A 42443:[DB00399 DB00056] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00056|Gemtuzumab ozogamicin CD33;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0016032| viral reproduction FDPS;FCGR2B 42444:[DB00399 DB00996] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00996|Gabapentin CACNA2D1;CACNA2D2;CACNA1B;ADORA1;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GABBR1;GABBR2;BCAT1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0042493| response to drug GRIN2A;ABCC1 GO:0055085| transmembrane transport CACNA1B;ABCC1 GO:0006810| transport CACNA1B;ABCC1;GRIN2C;GRIN2A;GRIN2B GO:0008202| steroid metabolic process FDPS;CYP3A4 42445:[DB00399 DB08970] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB08970|Fluprednidene CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 42446:[DB00399 DB06637] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06637|Dalfampridine KCNA1;KCNA2;KCNA3;KCNA4;KCNA5;KCNA6;KCNA7;KCNA10;KCNB1;KCNB2;KCNC1;KCNC2;KCNC3;KCND1;KCND2;KCND3;CYP2E1;SLC22A2 common genes common pathways GO:0006855| drug transmembrane transport ABCC1;SLC22A2 GO:0042493| response to drug ABCC1;CYP2E1 GO:0008202| steroid metabolic process CYP2E1;FDPS GO:0055085| transmembrane transport KCNA7;KCNA1;KCND3;KCNA10;KCNC1;KCNA6;KCNB1;KCNA5;KCNC3;KCNA3;ABCC1;KCND1;KCNC2;KCNA2;KCNB2;SLC22A2;KCNA4;KCND2 42447:[DB00399 DB00722] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00722|Lisinopril ACE common genes common pathways 42448:[DB00399 DB06207] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06207|Silodosin ADRA1A;ADRA1B;ADRA1D;CYP3A4;UGT2B7;ABCB1;ABCB4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;UGT2B7 GO:0006810| transport ABCC1;ABCB4;ABCB1 GO:0055085| transmembrane transport ABCB4;ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1;ABCB4;ADRA1A GO:0045332| phospholipid translocation ABCB1;ABCC1;ABCB4 GO:0042908| xenobiotic transport ABCB1;ABCB4;ABCC1 GO:0006855| drug transmembrane transport ABCB4;ABCC1;ABCB1 GO:0006629| lipid metabolic process UGT2B7;ABCB4;FDPS;CYP3A4 42449:[DB00399 DB01259] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01259|Lapatinib EGFR;ERBB2;CYP3A4;CYP3A5;CYP2C8;CYP2C19;ABCB1;TAP1 common genes common pathways GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0016032| viral reproduction FDPS;TAP1 GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP2C19;CYP2C8;CYP3A5 GO:0006810| transport ABCC1;ABCB1 GO:0055085| transmembrane transport ABCC1;TAP1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 42450:[DB00399 DB01406] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01406|Danazol ESR1;AR;PGR;GNRHR;GNRHR2;CCL2;CYP19A1;CYP3A4;SHBG common genes common pathways GO:0006694| steroid biosynthetic process CYP19A1;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport ABCC1;AR GO:0006629| lipid metabolic process CYP3A4;FDPS 42451:[DB00399 DB00862] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00862|Vardenafil PDE5A;PDE6G;PDE6H;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0055085| transmembrane transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS GO:0006810| transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS 42452:[DB00399 DB01215] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01215|Estazolam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0042493| response to drug GABRG3;ABCC1 GO:0006810| transport GABRG2;GABRA1;GABRB3;GABRD;GABRR2;ABCC1;GABRA4;GABRR1;GABRA6;GABRB1;GABRB2;GABRA3;GABRA5 GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 42453:[DB00399 DB00448] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00448|Lansoprazole ATP4A;MAPT;CYP1A1;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP2C19;ABCG2;ABCB1;SLC22A8 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;CYP2D6;FDPS;CYP3A4 GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCB1;ABCG2;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042493| response to drug ABCB1;CYP1A1;ABCG2;ABCC1 GO:0055085| transmembrane transport ABCG2;ABCC1;SLC22A8;ABCB1 GO:0006810| transport ATP4A;ABCB1;ABCC1;ABCG2 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP1A1;CYP3A4;CYP1B1;FDPS;CYP2D6;CYP2C9 42454:[DB00399 DB01181] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01181|Ifosfamide NR1I2;CYP2B6;CYP3A4;CYP3A5;CYP2C19;CYP2C9;CYP2C8;CYP2A6;CYP2C18;PTGS1 common genes common pathways GO:0008202| steroid metabolic process CYP3A5;CYP2C8;CYP2C19;FDPS;CYP2C9;NR1I2;CYP2B6;CYP3A4;CYP2A6 GO:0006629| lipid metabolic process PTGS1;CYP3A4;CYP2C9;FDPS GO:0042908| xenobiotic transport NR1I2;ABCC1 42455:[DB00399 DB06708] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06708|Lumefantrine CYP3A4;CYP2D6 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP2D6 GO:0008202| steroid metabolic process CYP2D6;FDPS;CYP3A4 42456:[DB00399 DB00672] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00672|Chlorpropamide ABCC8;CYP2C9;CYP2C19;PTGS1;SLC15A1;SLC15A2;SLC22A6 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP2C9;PTGS1 GO:0006810| transport ABCC1;SLC15A2;SLC15A1 GO:0008202| steroid metabolic process CYP2C9;FDPS;CYP2C19 GO:0055085| transmembrane transport ABCC1;ABCC8;SLC22A6;SLC15A2;SLC15A1 GO:0042493| response to drug ABCC8;ABCC1 GO:0099133| ABCC1;ABCC8 42457:[DB00399 DB11079] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11079|Trolamine salicylate PTGS1;PTGS2 common genes common pathways GO:0042493| response to drug PTGS2;ABCC1 GO:0006629| lipid metabolic process PTGS2;PTGS1;FDPS 42458:[DB00399 DB13170] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13170|Plecanatide GUCY1A2 common genes common pathways 42459:[DB00399 DB01073] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01073|Fludarabine RRM1;POLA1;DCK;SLC29A1;SLC28A3 common genes common pathways GO:0016032| viral reproduction FDPS;POLA1 42460:[DB00399 DB00092] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00092|Alefacept CD2;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B common genes common pathways GO:0016032| viral reproduction FCGR2B;FDPS 42461:[DB00399 DB13983] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB13983|5,7,2′-trihydroxy-6,8-dimethoxyflavone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0042493| response to drug ABCC1;GABRG3 GO:0006810| transport GABRA1;GABRG2;GABRA5;GABRA3;ABCC1;GABRA4;GABRA6 42462:[DB00399 DB00990] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00990|Exemestane CYP19A1;CYP3A4;CYP19A1 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0008202| steroid metabolic process CYP3A4;FDPS 42463:[DB00399 DB11750] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11750|Clobetasol CYP3A4 common genes common pathways GO:0008202| steroid metabolic process FDPS;CYP3A4 GO:0006629| lipid metabolic process CYP3A4;FDPS 42464:[DB00399 DB00484] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00484|Brimonidine ADRA2A;ADRA2B;ADRA2C;AOX1 common genes common pathways 42465:[DB00399 DB05207] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05207|SD118 TNF;IL1R1 common genes common pathways 42466:[DB00399 DB11737] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11737|Icotinib EGFR;CYP3A4;CYP1A2;CYP3A5 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS;CYP1A2;CYP3A5 GO:0042493| response to drug CYP1A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2 42467:[DB00399 DB11098] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11098|Potassium bicarbonate SLC12A2;SLC12A1 common genes common pathways GO:0006810| transport SLC12A2;ABCC1;SLC12A1 GO:0055085| transmembrane transport ABCC1;SLC12A1;SLC12A2 42468:[DB00399 DB00316] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00316|Acetaminophen PTGS2;PTGS1;FAAH;TRPV1;GSTP1;CYP2E1;CYP1A2;CYP3A4;CYP2D6;CYP1A1;CYP2A6;CYP2C8;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9;SLC22A6;ABCB1 common genes common pathways GO:0042493| response to drug ABCB1;CYP1A2;UGT1A1;ABCC1;PTGS2;CYP1A1;CYP2E1 GO:0006810| transport ABCB1;TRPV1;ABCC1 GO:0008202| steroid metabolic process SULT2A1;CYP3A4;CYP2A6;CYP2D6;SULT1E1;CYP2C9;FDPS;CYP1A2;SULT1A1;SULT1A3;CYP2C8;UGT1A1;UGT2B15;CYP1A1;CYP2E1 GO:0055085| transmembrane transport ABCB1;SLC22A6;TRPV1;ABCC1 GO:0006629| lipid metabolic process CYP3A4;SULT2A1;CYP2C9;CYP2D6;CYP1A2;FDPS;SULT1A3;SULT1A1;PTGS2;TRPV1;PTGS1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 42469:[DB00399 DB09297] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB09297|Paritaprevir CYP3A4;CYP3A5;ABCG2;ABCB1;SLCO1B1;SLCO1B3 common genes common pathways GO:0006855| drug transmembrane transport ABCG2;ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0042908| xenobiotic transport ABCG2;ABCC1;ABCB1 GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0055085| transmembrane transport SLCO1B1;ABCG2;ABCC1;SLCO1B3;ABCB1 GO:0008202| steroid metabolic process CYP3A5;CYP3A4;FDPS GO:0006810| transport ABCB1;ABCG2;ABCC1 GO:0042493| response to drug ABCB1;ABCG2;ABCC1 42470:[DB00399 DB00905] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00905|Bimatoprost PTGFR;PTGER1;PTGER3;AKR1C3 common genes common pathways GO:0008202| steroid metabolic process FDPS;AKR1C3 42471:[DB00399 DB01225] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01225|Enoxaparin SERPINC1;F10;MPO common genes common pathways 42472:[DB00399 DB01020] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01020|Isosorbide Mononitrate GUCY1A2;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42473:[DB00399 DB01260] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01260|Desonide NR3C1;CYP3A4 common genes common pathways GO:0006629| lipid metabolic process FDPS;CYP3A4 GO:0008202| steroid metabolic process FDPS;CYP3A4 42474:[DB00399 DB05624] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05624|Teverelix GNRHR common genes common pathways 42475:[DB00399 DB01065] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01065|Melatonin MTNR1A;MTNR1B;ESR1;RORB;CALM1;MPO;EPX;CALR;ASMT;NQO2;CYP1A1;CYP1A2;CYP1B1;CYP2C19;CYP2C9;ASMT;IDO1;MPO;CYP19A1;SLC22A8 common genes common pathways GO:0042493| response to drug CYP1A1;CALR;ABCC1;CYP1A2 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0055085| transmembrane transport CALM1;ABCC1;SLC22A8 GO:0008202| steroid metabolic process CYP1A2;FDPS;CYP2C9;CYP1B1;CYP1A1;CYP2C19 GO:0006629| lipid metabolic process CYP1A2;FDPS;CYP2C9 42476:[DB00399 DB04830] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04830|Buformin SLC22A1 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;ABCC1 GO:0055085| transmembrane transport ABCC1;SLC22A1 42477:[DB00399 DB06681] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06681|Belatacept CD86;CD80 common genes common pathways GO:0016032| viral reproduction CD80;FDPS;CD86 42478:[DB00399 DB01535] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01535|Carfentanil OPRM1;OPRD1;OPRK1 common genes common pathways 42479:[DB00399 DB00679] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00679|Thioridazine DRD2;DRD1;ADRA1A;ADRA1B;HTR2A;KCNH2;CYP2D6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways GO:0042493| response to drug ADRA1A;DRD2;CYP2E1;HTR2A;DRD1;ABCC1 GO:0055085| transmembrane transport KCNH2;ABCC1 GO:0008202| steroid metabolic process CYP2C19;CYP2C8;CYP2E1;FDPS;CYP2D6 GO:0016032| viral reproduction HTR2A;FDPS GO:0006629| lipid metabolic process CYP2D6;FDPS 42480:[DB00399 DB00280] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00280|Disopyramide SCN5A;CHRM1;CHRM2;CHRM3;KCND2;KCND3;KCNH2;ORM2;CYP3A4;CYP1A2;ORM1;SLC22A1;SLC22A2 common genes common pathways GO:0006855| drug transmembrane transport SLC22A1;SLC22A2;ABCC1 GO:0006629| lipid metabolic process CYP3A4;FDPS;CYP1A2 GO:0055085| transmembrane transport KCND3;KCNH2;SLC22A1;SCN5A;ABCC1;KCND2;SLC22A2 GO:0008202| steroid metabolic process CYP3A4;CYP1A2;FDPS GO:0042493| response to drug ABCC1;CYP1A2 42481:[DB00399 DB06897] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB06897|3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol PLK1 common genes common pathways 42482:[DB00399 DB01381] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01381|Ginkgo biloba SLC6A2;PLA2G2A;GLRA1;GABRA1;GABRB2;GABRG2;CYP2C9 common genes common pathways GO:0006629| lipid metabolic process CYP2C9;FDPS;PLA2G2A GO:0042493| response to drug SLC6A2;ABCC1 GO:0008202| steroid metabolic process CYP2C9;FDPS GO:0006810| transport GABRB2;ABCC1;SLC6A2;GABRA1;GABRG2 GO:0055085| transmembrane transport SLC6A2;ABCC1 42483:[DB00399 DB01208] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01208|Sparfloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2;ABCB1 common genes common pathways GO:0006629| lipid metabolic process CYP1A2;FDPS GO:0045332| phospholipid translocation ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCB1;ABCC1 GO:0006855| drug transmembrane transport SLC22A5;ABCC1;ABCB1;ABCC2 GO:0042493| response to drug CYP1A2;ABCC2;ABCB1;ABCC1 GO:0099133| ABCC1;ABCC2 GO:0008202| steroid metabolic process CYP1A2;FDPS GO:0006810| transport ABCC2;ABCB1;ABCC1 GO:0055085| transmembrane transport ABCB1;ABCC2;ABCC1;SLC22A5 42484:[DB00399 DB01166] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01166|Cilostazol PDE3A;CYP3A5;CYP3A7;CYP2C19;CYP3A4;CYP1A2;CYP2D6 common genes common pathways GO:0008202| steroid metabolic process CYP2C19;CYP3A5;CYP3A7;CYP3A4;CYP2D6;FDPS;CYP1A2 GO:0042493| response to drug PDE3A;ABCC1;CYP1A2 GO:0006629| lipid metabolic process CYP3A4;CYP1A2;FDPS;CYP2D6;PDE3A 42485:[DB00399 DB05311] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05311|Ecallantide KLKB1 common genes common pathways 42486:[DB00399 DB01241] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01241|Gemfibrozil PPARA;CYP2C8;CYP1A2;CYP2C19;CYP2C9;UGT1A1;CYP3A4;UGT1A3;SLCO1B1 common genes common pathways GO:0006629| lipid metabolic process PPARA;CYP3A4;CYP1A2;FDPS;CYP2C9 GO:0042493| response to drug ABCC1;UGT1A1;CYP1A2 GO:0008202| steroid metabolic process UGT1A1;CYP2C19;CYP2C8;CYP3A4;CYP1A2;FDPS;CYP2C9 GO:0055085| transmembrane transport ABCC1;SLCO1B1 42487:[DB00399 DB00778] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00778|Roxithromycin rplJ;ABCB1;CYP3A4;CYP2B6 common genes common pathways GO:0006810| transport ABCB1;ABCC1 GO:0008202| steroid metabolic process CYP2B6;FDPS;CYP3A4 GO:0055085| transmembrane transport ABCC1;ABCB1 GO:0042493| response to drug ABCB1;ABCC1 GO:0042908| xenobiotic transport ABCC1;ABCB1 GO:0045332| phospholipid translocation ABCC1;ABCB1 GO:0006855| drug transmembrane transport ABCC1;ABCB1 GO:0006629| lipid metabolic process CYP3A4;FDPS 42488:[DB00399 DB11475] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB11475|Tylosin CYP3A4 common genes common pathways GO:0006629| lipid metabolic process CYP3A4;FDPS GO:0008202| steroid metabolic process CYP3A4;FDPS 42489:[DB00399 DB05465] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB05465|Tandutinib FLT3;PDGFD common genes common pathways 42490:[DB00399 DB00181] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB00181|Baclofen GABBR1;GABBR2;SLC22A8 common genes common pathways GO:0055085| transmembrane transport SLC22A8;ABCC1 42491:[DB00399 DB04839] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB04839|Cyproterone acetate AR;KLK3;CYP19A1;CYP3A4 common genes common pathways GO:0008202| steroid metabolic process CYP3A4;FDPS GO:0006810| transport AR;ABCC1 GO:0006694| steroid biosynthetic process FDPS;CYP19A1 GO:0006629| lipid metabolic process CYP3A4;FDPS 42492:[DB00399 DB01276] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01276|Exenatide GLP1R;ALB common genes common pathways 42493:[DB00399 DB01949] DB00399|Zoledronic acid FDPS;GGPS1;ABCC1 DB01949|2-Amino-N,3,3-Trimethylbutanamide MMP9 common genes common pathways 42494:[DB02873 DB00540] DB02873|1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One MAPK14 DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0035556| intracellular signal transduction MAPK14;DRD2;ADRA1A;ADRA1B GO:0007166| cell surface receptor linked signaling pathway ADRB2;MAPK14;CHRM4 GO:0007165| signal transduction ADRA1B;HTR1A;ADRB1;ADRA2B;HTR2A;DRD2;ADRA1A;ADRB3;CHRM1;CHRM4;ADRA1D;MAPK14;HRH1;CHRM5;ADRB2;CHRM2;ADRA2C;HTR2C;HTR6;ADRA2A;CHRM3 GO:0043312| neutrophil degranulation ORM1;MAPK14;PGRMC1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MAPK14;ADRB2;DRD2 GO:0007265| Ras protein signal transduction ADRA2A;MAPK14 GO:0032496| response to lipopolysaccharide CYP1A2;MAPK14 GO:0010628| positive regulation of gene expression MAPK14;SLC6A4 GO:0006928| cellular component movement ADRA2A;MAPK14 GO:0006915| apoptotic process MAPK14;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;MAPK14 42495:[DB02873 DB01151] DB02873|1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One MAPK14 DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0006915| apoptotic process MAPK14;ADRA1A GO:0000187| activation of MAPK activity ADRA2B;MAPK14 GO:0010628| positive regulation of gene expression MAPK14;SLC6A4 GO:0006928| cellular component movement MAPK14;ADRA2A GO:0032496| response to lipopolysaccharide MAPK14;CYP1A2 GO:0007265| Ras protein signal transduction MAPK14;ADRA2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MAPK14;ADRB2 GO:0043312| neutrophil degranulation ORM1;MAPK14 GO:0007165| signal transduction DRD2;ADRA1A;HTR2A;ADRA2B;ADRB1;SMPD1;ADRA1B;HTR1A;HTR2C;ADRA2A;CHRM3;ADRB2;CHRM2;ADRA2C;HRH1;CHRM5;CHRM4;MAPK14;ADRA1D;CHRM1 GO:0007166| cell surface receptor linked signaling pathway MAPK14;CHRM4;ADRB2 GO:0035556| intracellular signal transduction ADRA1B;DRD2;ADRA1A;MAPK14 42496:[DB02873 DB00571] DB02873|1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One MAPK14 DB00571|Propranolol ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;CYP3A5;CYP2D6;CYP3A7;CYP1A2;CYP2C19;CYP3A4;CYP1A1;MAOA;ORM1;SLC22A2;ABCB1 common genes common pathways GO:0043312| neutrophil degranulation ORM1;MAPK14 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MAPK14 GO:0032496| response to lipopolysaccharide CYP1A1;MAPK14;CYP1A2 GO:0007165| signal transduction ADRB1;HTR1A;ADRB3;MAPK14;HTR1B;ADRB2 GO:0007166| cell surface receptor linked signaling pathway MAPK14;ADRB2 42497:[DB06314 DB07543] DB06314|SGX-523 MET DB07543|(2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0007165| signal transduction MET;ADRB2 42498:[DB06314 DB11730] DB06314|SGX-523 MET DB11730|Ribociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0007165| signal transduction CDK4;CDK6;MET GO:0016310| phosphorylation MET;CDK4;CDK6 GO:0006468| protein phosphorylation CDK4;CDK6;MET 42499:[DB06314 DB00413] DB06314|SGX-523 MET DB00413|Pramipexole DRD3;DRD2;DRD4;ADRA2B;HTR1A;HTR1D;ADRA2A;HTR1B;HTR2A;HTR2B;HTR2C;ADRA2C;DRD1;DRD5;SLC22A2;SLC22A1 common genes common pathways GO:0016310| phosphorylation MET;HTR2B GO:0007165| signal transduction ADRA2C;MET;HTR2C;ADRA2A;DRD5;DRD3;HTR1B;DRD4;ADRA2B;HTR2A;DRD1;DRD2;HTR1A;HTR1D;HTR2B GO:0008283| cell proliferation HTR1A;MET GO:0010507| negative regulation of autophagy HTR2B;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET 42500:[DB06314 DB01224] DB06314|SGX-523 MET DB01224|Quetiapine HTR2A;DRD2;HTR1A;HTR1B;HTR1D;HTR1E;HTR2C;HTR3A;HTR6;HTR7;DRD1;DRD5;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A5;CYP3A7;CYP3A4;CYP2C19;CYP2D6;ABCB1 common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA2C;CHRM2;MET;CHRM5;HRH1;HTR6;HTR2C;ADRA2A;CHRM3;HTR1E;DRD5;CHRM1;HTR1B;HTR7;CHRM4;DRD3;ADRA1D;DRD1;DRD4;HTR2A;ADRA2B;ADRA1A;DRD2;HTR3A;ADRA1B;HTR1A;HTR1D GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation CHRM1;ADRA1D;CHRM4;MET;CHRM5;CHRM3;HTR1A;ADRA1B GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD3;DRD2 42501:[DB06314 DB06605] DB06314|SGX-523 MET DB06605|Apixaban F10;CYP3A4;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;F10 42502:[DB06314 DB01179] DB06314|SGX-523 MET DB01179|Podofilox TOP2A;TUBA4A;TUBB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 42503:[DB06314 DB05127] DB06314|SGX-523 MET DB05127|ANA971 TLR7 common genes common pathways GO:0007165| signal transduction TLR7;MET 42504:[DB06314 DB01148] DB06314|SGX-523 MET DB01148|Flavoxate CHRM2;CHRM1 common genes common pathways GO:0008283| cell proliferation CHRM1;MET GO:0007165| signal transduction CHRM1;CHRM2;MET 42505:[DB06314 DB01594] DB06314|SGX-523 MET DB01594|Cinolazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3 common genes common pathways GO:0007165| signal transduction GABRB1;GABRD;GABRR2;GABRA5;GABRE;GABRP;GABRB3;MET 42506:[DB06314 DB00645] DB06314|SGX-523 MET DB00645|Dyclonine SCN10A common genes common pathways 42507:[DB06314 DB06725] DB06314|SGX-523 MET DB06725|Lornoxicam PTGS1;PTGS2;CYP2C9 common genes common pathways 42508:[DB06314 DB04863] DB06314|SGX-523 MET DB04863|Lefradafiban ITGA2B;ITGB3 common genes common pathways 42509:[DB06314 DB00232] DB06314|SGX-523 MET DB00232|Methyclothiazide SLC12A1;CA1;CA2;CA4 common genes common pathways 42510:[DB06314 DB01580] DB06314|SGX-523 MET DB01580|Oxprenolol ADRB1;ADRB2;ADRB3;CYP2D6;SLC22A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction ADRB2;MET;ADRB3;ADRB1 42511:[DB06314 DB00838] DB06314|SGX-523 MET DB00838|Clocortolone NR3C1 common genes common pathways GO:0007165| signal transduction MET;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 42512:[DB06314 DB00196] DB06314|SGX-523 MET DB00196|Fluconazole CYP3A4;CYP2C9;CYP2C19;CYP3A5;CYP3A7;CYP11B1;ABCB1 common genes common pathways 42513:[DB06314 DB02789] DB06314|SGX-523 MET DB02789|Pregnenolone SULT2B1;NR1I2;CYP3A4;SLC10A6 common genes common pathways GO:0007165| signal transduction NR1I2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2 42514:[DB06314 DB08911] DB06314|SGX-523 MET DB08911|Trametinib MAP2K1;MAP2K2;CYP2C8;CYP3A4 common genes common pathways GO:0006468| protein phosphorylation MAP2K2;MET;MAP2K1 GO:0016310| phosphorylation MAP2K1;MAP2K2;MET GO:0007165| signal transduction MET;MAP2K1 GO:0000165| MAPKKK cascade MAP2K1;MET;MAP2K2 GO:0018108| peptidyl-tyrosine phosphorylation MAP2K2;MET;MAP2K1 42515:[DB06314 DB00087] DB06314|SGX-523 MET DB00087|Alemtuzumab CD52;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction MET;FCGR1A;FCGR2C;FCGR2B 42516:[DB06314 DB01415] DB06314|SGX-523 MET DB01415|Ceftibuten mrcA;SLC15A1;SLC15A2;SLC22A6;SLC22A8 common genes common pathways 42517:[DB06314 DB06803] DB06314|SGX-523 MET DB06803|Niclosamide CYP2C9;CYP1A2 common genes common pathways 42518:[DB06314 DB00175] DB06314|SGX-523 MET DB00175|Pravastatin HMGCR;CYP2C8;SLCO1B1;SLCO2B1;ABCB1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;SLC22A11;ABCG2;SLC22A7;SLC16A1;ABCB11;SLCO1B3 common genes common pathways 42519:[DB06314 DB00940] DB06314|SGX-523 MET DB00940|Methantheline CHRM1;HRH2 common genes common pathways GO:0008283| cell proliferation CHRM1;MET GO:0007165| signal transduction HRH2;MET;CHRM1 42520:[DB06314 DB09422] DB06314|SGX-523 MET DB09422|Soybean oil PPARA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARA;MET 42521:[DB06314 DB00098] DB06314|SGX-523 MET DB00098|Antithymocyte immunoglobulin (rabbit) CD1A;MR1;ITGAL;CD86;FCGR2B;CD4;ITGB1;ITGAV;ITGB3 common genes common pathways GO:0007165| signal transduction CD86;MET;CD4;ITGAL;MR1;FCGR2B GO:0035024| negative regulation of Rho protein signal transduction ITGB1;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;CD4 GO:0007166| cell surface receptor linked signaling pathway CD4;MET GO:0046854| phosphatidylinositol phosphorylation MET;CD86 GO:0051897| positive regulation of protein kinase B signaling cascade MET;CD86;ITGB1 42522:[DB06314 DB00816] DB06314|SGX-523 MET DB00816|Orciprenaline ADRB2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0007165| signal transduction ADRB2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 42523:[DB06314 DB00543] DB06314|SGX-523 MET DB00543|Amoxapine SLC6A2;SLC6A4;DRD2;DRD1;ADRA2A;ADRA1A;CHRM1;GABRA1;HTR2A;HTR2C;HTR6;HTR7;DRD3;DRD4;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2B;HTR3A;HTR1A;HTR1B;ADRA2A;ADRA2B;ADRA2C;HRH4;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;SLC6A3;CYP2D6;ORM1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0007165| signal transduction GABRB3;CHRM2;HRH4;ADRA2C;HRH1;MET;CHRM5;ADRA2A;HTR6;HTR2C;CHRM3;CHRM1;GABRQ;GABRE;HTR7;CHRM4;HTR1B;DRD3;GABRP;ADRA1D;DRD1;HTR2A;ADRA2B;DRD4;HTR3A;ADRA1A;DRD2;GABRA5;ADRA1B;HTR1A;GABRA6;GABRB1;HTR2B;GABRD GO:0016310| phosphorylation MET;HTR2B GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0010507| negative regulation of autophagy HTR2B;ADRA1A;MET GO:0008283| cell proliferation CHRM3;MET;CHRM5;ADRA1D;CHRM4;CHRM1;HTR1A;ADRA1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET 42524:[DB06314 DB00936] DB06314|SGX-523 MET DB00936|Salicylic acid PTGS1;PTGS2;AKR1C1;CYP2C9;ALB;SLC22A6;SLC22A10;SLC22A8;SLC22A11;SLCO2B1;SLC16A1;SLC22A7 common genes common pathways 42525:[DB06314 DB01165] DB06314|SGX-523 MET DB01165|Ofloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC1;SLC22A6;ABCC2;SLC22A4;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 42526:[DB06314 DB00671] DB06314|SGX-523 MET DB00671|Cefixime SLC22A5;SLC15A1;SLC15A2 common genes common pathways 42527:[DB06314 DB03410] DB06314|SGX-523 MET DB03410|4-hydroxycoumarin CYP3A4 common genes common pathways 42528:[DB06314 DB06685] DB06314|SGX-523 MET DB06685|Laquinimod CYP3A4 common genes common pathways 42529:[DB06314 DB01618] DB06314|SGX-523 MET DB01618|Molindone DRD2;HTR1A;HTR2A;CHRM1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0008283| cell proliferation MET;CHRM1;HTR1A GO:0007165| signal transduction MET;CHRM1;DRD2;HTR2A;HTR1A 42530:[DB06314 DB08894] DB06314|SGX-523 MET DB08894|Peginesatide EPOR common genes common pathways GO:0007165| signal transduction EPOR;MET 42531:[DB06314 DB05111] DB06314|SGX-523 MET DB05111|Fontolizumab IFNG common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;IFNG 42532:[DB06314 DB01023] DB06314|SGX-523 MET DB01023|Felodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1H;CACNA2D2;CALM1;PDE1B;PDE1A;NR3C2;TNNC2;TNNC1;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2C9;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0000165| MAPKKK cascade CALM1;MET GO:0007165| signal transduction PDE1A;PDE1B;NR3C2;MET 42533:[DB06314 DB00617] DB06314|SGX-523 MET DB00617|Paramethadione CACNA1I;CYP2E1;CYP3A4;CYP2C9;CYP2C8 common genes common pathways GO:0007165| signal transduction CACNA1I;MET 42534:[DB06314 DB01029] DB06314|SGX-523 MET DB01029|Irbesartan AGTR1;JUN;CYP2C8;CYP2C9;UGT1A3;PTGS1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter JUN;MET GO:0007165| signal transduction MET;AGTR1 42535:[DB06314 DB01436] DB06314|SGX-523 MET DB01436|Alfacalcidol VDR;CYP27B1;RXRA;GC common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;MET;VDR GO:0007165| signal transduction MET;VDR 42536:[DB06314 DB00681] DB06314|SGX-523 MET DB00681|Amphotericin B CYP3A4 common genes common pathways 42537:[DB06314 DB00866] DB06314|SGX-523 MET DB00866|Alprenolol ADRB1;ADRB2;HTR1A;ADRB3;CYP2D6 common genes common pathways GO:0007165| signal transduction MET;ADRB2;ADRB3;ADRB1;HTR1A GO:0008283| cell proliferation MET;HTR1A GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 42538:[DB06314 DB06233] DB06314|SGX-523 MET DB06233|Ridaforolimus MTOR;CYP3A4 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;MET GO:0010507| negative regulation of autophagy MET;MTOR GO:0006468| protein phosphorylation MET;MTOR GO:0016310| phosphorylation MET;MTOR GO:0007165| signal transduction MTOR;MET 42539:[DB06314 DB00843] DB06314|SGX-523 MET DB00843|Donepezil ACHE;HTR2A;CYP2D6;CYP3A4;CYP2C9 common genes common pathways GO:0007165| signal transduction HTR2A;MET GO:0008283| cell proliferation MET;ACHE 42540:[DB06314 DB00987] DB06314|SGX-523 MET DB00987|Cytarabine POLB;CDA;CYP3A4;DCK;NT5E;DCTD;SLC22A1;ABCC10;SLC29A1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CDA;MET GO:0016310| phosphorylation DCK;MET 42541:[DB06314 DB11785] DB06314|SGX-523 MET DB11785|Anisodamine CYP2D6 common genes common pathways 42542:[DB06314 DB05258] DB06314|SGX-523 MET DB05258|Natural alpha interferon IFNAR1 common genes common pathways 42543:[DB06314 DB08864] DB06314|SGX-523 MET DB08864|Rilpivirine pol;NR1I2;CYP3A4;CYP2C19;CYP2B6;CYP2D6;ALB;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2 GO:0007165| signal transduction NR1I2;MET 42544:[DB06314 DB09160] DB06314|SGX-523 MET DB09160|Technetium Tc-99m tetrofosmin ABCB1 common genes common pathways 42545:[DB06314 DB12872] DB06314|SGX-523 MET DB12872|Vonicog Alfa F8;COL1A1;ADAMTS13 common genes common pathways 42546:[DB06314 DB00135] DB06314|SGX-523 MET DB00135|L-Tyrosine TH;YARS2;YARS;TAT;SLC16A2;SLC16A10 common genes common pathways GO:0007165| signal transduction YARS;MET 42547:[DB06314 DB08877] DB06314|SGX-523 MET DB08877|Ruxolitinib JAK1;JAK2;CYP3A4 common genes common pathways GO:0000165| MAPKKK cascade JAK2;MET;JAK1 GO:0018108| peptidyl-tyrosine phosphorylation MET;JAK2 GO:0006468| protein phosphorylation JAK1;MET;JAK2 GO:0016310| phosphorylation JAK2;JAK1;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway JAK1;MET GO:0007165| signal transduction MET;JAK2 42548:[DB06314 DB11641] DB06314|SGX-523 MET DB11641|Vinflunine TUBB;CYP3A4;ALB;ORM1;ORM2;ABCB5;ABCB1 common genes common pathways 42549:[DB06314 DB00654] DB06314|SGX-523 MET DB00654|Latanoprost PTGFR;SLCO2B1;SLC22A1 common genes common pathways GO:0007165| signal transduction MET;PTGFR 42550:[DB06314 DB01211] DB06314|SGX-523 MET DB01211|Clarithromycin rplJ;KCNH2;SLCO1B1;SLCO1B3;CYP3A4;CYP3A5;CYP2C19;CYP3A7;SLC22A7;ABCB1;ABCB11 common genes common pathways 42551:[DB06314 DB00292] DB06314|SGX-523 MET DB00292|Etomidate GABRA1;ADRA2B;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP11B1;CYP11B2;CYP19A1;SLC2A1 common genes common pathways GO:0007165| signal transduction GABRD;GABRA6;GABRB1;GABRA5;ADRA2B;GABRP;GABRE;GABRQ;GABRB3;MET 42552:[DB06314 DB01218] DB06314|SGX-523 MET DB01218|Halofantrine KCNH2;CYP2D6;CYP3A4;CYP3A5;CYP2C8 common genes common pathways 42553:[DB06314 DB01099] DB06314|SGX-523 MET DB01099|Flucytosine DNMT1 common genes common pathways 42554:[DB06314 DB01204] DB06314|SGX-523 MET DB01204|Mitoxantrone TOP2A;CYP2E1;CYP1B1;CYP3A4;ABCB1;ABCC1;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 42555:[DB06314 DB06267] DB06314|SGX-523 MET DB06267|Udenafil PDE5A;CYP3A4;CYP3A5 common genes common pathways GO:0007165| signal transduction MET;PDE5A 42556:[DB06314 DB06660] DB06314|SGX-523 MET DB06660|Saredutant TACR2 common genes common pathways GO:0007165| signal transduction TACR2;MET 42557:[DB06314 DB09090] DB06314|SGX-523 MET DB09090|Pinaverium CACNA1S;CYP3A4 common genes common pathways 42558:[DB06314 DB12836] DB06314|SGX-523 MET DB12836|Grapiprant PTGER4;ALB;ABCB1 common genes common pathways GO:0007165| signal transduction MET;PTGER4 42559:[DB06314 DB00139] DB06314|SGX-523 MET DB00139|Succinic acid SDHC;SUCNR1;OXCT2;TMLHE;SUCLA2;SLC25A10;SDHA;HSD17B6;SLC13A3;SLC13A2;SLC13A1;SUCLG2;SDHD;P4HA2;PLOD3;BBOX1;P4HA1;SDHB;ALDH5A1;SUCLG1;OXCT1;PLOD1;ASPH;P3H1;P3H2;P3H3;SLC22A8 common genes common pathways GO:0001886| endothelial cell morphogenesis PLOD3;MET GO:0007165| signal transduction SUCNR1;MET 42560:[DB06314 DB06156] DB06314|SGX-523 MET DB06156|Tesofensine SLC6A4;SLC6A2;SLC6A3 common genes common pathways 42561:[DB06314 DB06701] DB06314|SGX-523 MET DB06701|Dexmethylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways 42562:[DB06314 DB00736] DB06314|SGX-523 MET DB00736|Esomeprazole ATP4A;CYP2C19;CYP3A4 common genes common pathways 42563:[DB06314 DB01198] DB06314|SGX-523 MET DB01198|Zopiclone GABRA1;GABRA2;GABRA3;GABRA5;TSPO;CYP3A4;CYP2C8;CYP2C9;PTGS1;CYP2E1 common genes common pathways GO:0008283| cell proliferation MET;TSPO GO:0007165| signal transduction GABRA5;MET;TSPO 42564:[DB06314 DB04017] DB06314|SGX-523 MET DB04017|Clorgiline MAOA common genes common pathways 42565:[DB06314 DB00854] DB06314|SGX-523 MET DB00854|Levorphanol OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007165| signal transduction MET;OPRM1;OPRK1;OPRD1 42566:[DB06314 DB00493] DB06314|SGX-523 MET DB00493|Cefotaxime SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLC15A1;ALB;SLC15A2;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 42567:[DB06314 DB00623] DB06314|SGX-523 MET DB00623|Fluphenazine DRD2;DRD1;CALM1;AR;HTR2A;HTR2C;CYP2D6;CYP2E1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2;AR GO:0008283| cell proliferation MET;AR GO:0007165| signal transduction HTR2C;MET;DRD2;DRD1;AR;HTR2A GO:0000165| MAPKKK cascade CALM1;MET 42568:[DB06314 DB14050] DB06314|SGX-523 MET DB14050|Cannabidivarin TRPV1;TRPV2;TRPA1;DAGLA common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;MET;TRPV1 42569:[DB06314 DB01245] DB06314|SGX-523 MET DB01245|Decamethonium CHRNA2;ACHE;CHRNA4;CHRNB2;BCHE common genes common pathways GO:0007165| signal transduction CHRNA2;CHRNA4;MET;CHRNB2 GO:0008283| cell proliferation MET;ACHE 42570:[DB06314 DB00622] DB06314|SGX-523 MET DB00622|Nicardipine CACNA1C;CACNB2;CACNA2D1;CACNA1D;PDE1A;PDE1B;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CALM1;CYP3A4;CYP2D6;CYP2C19;CYP2C8;CYP2B6;CYP2E1;CYP3A5;ABCB1;SLCO1B1;ABCB11 common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1D;CHRM4;CHRM1;CHRM3;MET;CHRM5;CHRM2;PDE1B;ADRA1B;PDE1A;ADRA1A GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation CHRM4;ADRA1D;CHRM1;CHRM3;MET;CHRM5;ADRA1B GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0000165| MAPKKK cascade CALM1;MET 42571:[DB06314 DB05785] DB06314|SGX-523 MET DB05785|LGD-1550 RARA;RARB;RARG;JUN common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RARG;JUN;RARA;MET;RARB GO:0007165| signal transduction RARA;RARB;MET GO:0006468| protein phosphorylation MET;RARA 42572:[DB06314 DB00119] DB06314|SGX-523 MET DB00119|Pyruvic acid SLC16A3;SLC16A2;AGXT2;SLC16A5;PKLR;SLC16A6;SLC16A7;PDHB;PKM;ABAT;SLC16A4;SLC16A8;SLC16A1;PC;SLC16A7;SLC16A1;SLC16A10;SLCO2A1;SLC16A3 common genes common pathways GO:0016310| phosphorylation MET;PKLR;PKM 42573:[DB06314 DB01232] DB06314|SGX-523 MET DB01232|Saquinavir pol;CYP3A7;CYP3A5;CYP3A4;CYP11A1;CYP2C8;CYP2D6;ORM1;ALB;ABCB1;SLC22A1;SLCO1A2;ABCG2;SLCO1B1;ABCC1;ABCC2;SLCO2B1;ABCB11 common genes common pathways 42574:[DB06314 DB11201] DB06314|SGX-523 MET DB11201|Menthyl salicylate PTGS1;PTGS2 common genes common pathways 42575:[DB06314 DB00370] DB06314|SGX-523 MET DB00370|Mirtazapine HTR2A;HTR3A;ADRA2A;HTR2C;OPRK1;HRH1;ADRA2C;HTR7;ADRA1A;ADRA1B;ADRA1D;DRD2;DRD3;SLC6A2;SLC6A4;SLC6A3;HTR2B;DRD1;DRD5;HRH3;ADRA1A;ADRB1;ADRB2;CYP3A4;CYP2D6;CYP1A2;CYP2C9;CYP2C8 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0010507| negative regulation of autophagy HTR2B;ADRA1A;MET GO:0016310| phosphorylation MET;HTR2B GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction DRD1;HTR2A;ADRA1A;DRD2;HTR3A;ADRA1B;HRH3;ADRB1;HTR2B;MET;HRH1;ADRA2C;ADRB2;ADRA2A;HTR2C;DRD5;HTR7;OPRK1;ADRA1D;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2;DRD3;DRD2 42576:[DB06314 DB01118] DB06314|SGX-523 MET DB01118|Amiodarone KCNH2;ADRB1;CACNA1H;CACNA2D2;THRA;THRB;PPARG;CYP3A4;CYP2C8;CYP2D6;CYP2C9;CYP1A2;CYP2C19;CYP1A1;CYP3A5;CYP3A7;CYP2A6;ABCB1;ABCB11;SLC22A2 common genes common pathways GO:0007165| signal transduction MET;PPARG;ADRB1 GO:0008283| cell proliferation MET;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;PPARG;MET;THRB 42577:[DB06314 DB00392] DB06314|SGX-523 MET DB00392|Profenamine CHRM1;GRIN3A;CHRM2;BCHE common genes common pathways GO:0008283| cell proliferation CHRM1;MET GO:0007165| signal transduction CHRM2;MET;CHRM1 42578:[DB06314 DB00775] DB06314|SGX-523 MET DB00775|Tirofiban ITGA2B;ITGB3 common genes common pathways 42579:[DB06314 DB00768] DB06314|SGX-523 MET DB00768|Olopatadine HRH1;S100A1;S100A12;S100B;S100A13;S100A2;CYP3A4 common genes common pathways GO:0008283| cell proliferation S100B;MET GO:0007165| signal transduction MET;HRH1 42580:[DB06314 DB00483] DB06314|SGX-523 MET DB00483|Gallamine Triethiodide CHRM2;ACHE;CHRNA2;CHRM1;CHRM5 common genes common pathways GO:0007165| signal transduction CHRM2;CHRM5;MET;CHRM1;CHRNA2 GO:0008283| cell proliferation ACHE;CHRM1;CHRM5;MET 42581:[DB06314 DB00300] DB06314|SGX-523 MET DB00300|Tenofovir disoproxil pol;AK2;AK4;NME1;NME2;SLC22A6;SLC22A8;ABCC10;ABCC4;ABCC2;ABCB1 common genes common pathways GO:0016310| phosphorylation MET;NME2;AK4;AK2;NME1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NME2 42582:[DB06314 DB00416] DB06314|SGX-523 MET DB00416|Metocurine Iodide CHRNA2 common genes common pathways GO:0007165| signal transduction CHRNA2;MET 42583:[DB06314 DB01036] DB06314|SGX-523 MET DB01036|Tolterodine CHRM3;CHRM2;CHRM5;CHRM1;CHRM4;CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways GO:0008283| cell proliferation CHRM1;CHRM4;CHRM5;MET;CHRM3 GO:0007165| signal transduction CHRM3;CHRM5;MET;CHRM2;CHRM4;CHRM1 GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 42584:[DB06314 DB01914] DB06314|SGX-523 MET DB01914|D-glucose HK1;GCK;SLC2A1;SLC2A2;SLC2A3;SLC2A4;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A9;SLC2A10;SLC2A11;SLC2A12;SLC5A1;SLC5A2 common genes common pathways GO:0016310| phosphorylation HK1;GCK;MET 42585:[DB06314 DB06506] DB06314|SGX-523 MET DB06506|Repinotan HTR1A;CYP2D6 common genes common pathways GO:0008283| cell proliferation MET;HTR1A GO:0007165| signal transduction HTR1A;MET 42586:[DB06314 DB00063] DB06314|SGX-523 MET DB00063|Eptifibatide ITGB3 common genes common pathways 42587:[DB06314 DB00960] DB06314|SGX-523 MET DB00960|Pindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0007165| signal transduction MET;ADRB2;HTR1B;ADRB3;ADRB1;HTR1A GO:0008283| cell proliferation MET;HTR1A GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 42588:[DB06314 DB14568] DB06314|SGX-523 MET DB14568|Ivosidenib IDH1;CYP3A4;CYP2B6;CYP2C9;CYP2C8;SLC22A8;ABCB1 common genes common pathways 42589:[DB06314 DB09273] DB06314|SGX-523 MET DB09273|Doxofylline PDE2A;ADORA2A;ADRB2;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007165| signal transduction ADRB2;MET;PDE2A;ADORA2A GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 42590:[DB06314 DB05308] DB06314|SGX-523 MET DB05308|ANX-510 TYMS common genes common pathways 42591:[DB06314 DB00290] DB06314|SGX-523 MET DB00290|Bleomycin LIG1;LIG3;BLMH common genes common pathways 42592:[DB06314 DB00732] DB06314|SGX-523 MET DB00732|Atracurium besylate CHRNA2 common genes common pathways GO:0007165| signal transduction MET;CHRNA2 42593:[DB06314 DB14597] DB06314|SGX-523 MET DB14597|Lanadelumab KLKB1 common genes common pathways 42594:[DB06314 DB00945] DB06314|SGX-523 MET DB00945|Acetylsalicylic acid PTGS1;PTGS2;AKR1C1;PRKAA1;PRKAA2;PRKAB1;PRKAB2;PRKAG1;PRKAG2;PRKAG3;EDNRA;IKBKB;TP53;HSPA5;RPS6KA3;NFKBIA;NFKB2;NFKB1;CYP2C19;CYP2C8;CYP2C9;ALB;SLC22A6;ABCB1;SLC22A7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;RPS6KA3;NFKB1;IKBKB;TP53;NFKBIA;NFKB2 GO:0008283| cell proliferation MET;EDNRA;TP53 GO:0007165| signal transduction PRKAB2;PRKAA1;RPS6KA3;PRKAA2;PRKAB1;MET;PRKAG1;NFKB2;NFKB1;EDNRA GO:0006468| protein phosphorylation PRKAG3;IKBKB;PRKAG1;PRKAB1;PRKAG2;MET;PRKAB2;PRKAA1;RPS6KA3;PRKAA2 GO:0016310| phosphorylation MET;PRKAA1;RPS6KA3;PRKAA2;IKBKB 42595:[DB06314 DB06739] DB06314|SGX-523 MET DB06739|Seratrodast TBXA2R;CYP2C9;CYP3A4;CYP2C8;CYP2C19;CYP2B6;UGT1A9;PTGS1;CYP2A6 common genes common pathways GO:0007165| signal transduction TBXA2R;MET 42596:[DB06314 DB00296] DB06314|SGX-523 MET DB00296|Ropivacaine SCN10A;CYP1A2;CYP2B6;CYP3A4 common genes common pathways 42597:[DB06314 DB07670] DB06314|SGX-523 MET DB07670|4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDE CYP2C18 common genes common pathways 42598:[DB06314 DB01079] DB06314|SGX-523 MET DB01079|Tegaserod HTR4;HTR2B;HTR2C;HTR2A;CYP1A2;CYP2C8;CYP2D6;CYP2E1;SLC6A4 common genes common pathways GO:0010507| negative regulation of autophagy MET;HTR2B GO:0016310| phosphorylation MET;HTR2B GO:0007165| signal transduction HTR2A;HTR2B;MET;HTR2C;HTR4 42599:[DB06314 DB01087] DB06314|SGX-523 MET DB01087|Primaquine KRT7;NQO2;CYP3A4;CYP1A2;CYP2D6;CYP1A1;CYP1B1;ABCB1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 42600:[DB06314 DB06247] DB06314|SGX-523 MET DB06247|CX516 GRIA1 common genes common pathways GO:0007165| signal transduction MET;GRIA1 42601:[DB06314 DB11753] DB06314|SGX-523 MET DB11753|Rifamycin rpoB;rpoA;rpoC;CYP3A4;CYP2C19;CYP2B6;CYP2C8;CYP2C9;CYP2D6;CYP1A2;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2A1;SLCO2B1;SLC47A1;ABCB1 common genes common pathways 42602:[DB06314 DB01124] DB06314|SGX-523 MET DB01124|Tolbutamide ABCC8;KCNJ1;CYP2C9;CYP2C8;CYP2C19;CYP2C18;ALB;SLC15A1;SLCO1A2;SLC22A6;SLC15A2;SLCO2B1 common genes common pathways GO:0007165| signal transduction MET;ABCC8 42603:[DB06314 DB00997] DB06314|SGX-523 MET DB00997|Doxorubicin TOP2A;NOLC1;CYP3A4;CYP2D6;CYP2B6;CYP1B1;CBR1;CBR3;AKR1A1;AKR1C3;NQO1;XDH;NOS1;NOS2;NOS3;NDUFS2;NDUFS3;NDUFS7;POR;ALB;ABCB1;ABCC1;ABCC3;ABCC6;ABCG2;SLC22A16;ABCC10;ABCB8;ABCB11;RALBP1;ABCC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;NOS1;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;AKR1C3 GO:0007165| signal transduction MET;RALBP1 42604:[DB06314 DB00266] DB06314|SGX-523 MET DB00266|Dicoumarol VKORC1;NQO1;CRYZ;CYP2C9;ALB common genes common pathways 42605:[DB06314 DB13783] DB06314|SGX-523 MET DB13783|Acemetacin PTGS1;PTGS2;UGT2B7;ABCC1 common genes common pathways 42606:[DB06314 DB00800] DB06314|SGX-523 MET DB00800|Fenoldopam DRD5;DRD1;ADRA2B;ADRA2C;ADRA2A;ADRA1B;ADRA1D;ADRA1A common genes common pathways GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction ADRA2C;MET;ADRA2A;DRD5;ADRA1D;ADRA2B;DRD1;ADRA1A;ADRA1B 42607:[DB06314 DB05676] DB06314|SGX-523 MET DB05676|Apremilast PDE4D;PDE4A;PDE4B;TNF;IL2;IFNG;NOS3;CYP3A4 common genes common pathways GO:0007165| signal transduction PDE4D;PDE4B;MET;PDE4A GO:0007166| cell surface receptor linked signaling pathway MET;IFNG GO:0000165| MAPKKK cascade TNF;IL2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;MET;IL2 GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF 42608:[DB06314 DB06694] DB06314|SGX-523 MET DB06694|Xylometazoline ADRA1A;ADRA2A;ADRA2B;ADRA1B;ADRA1D;ADRA2C common genes common pathways GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0007165| signal transduction ADRA1A;ADRA2B;ADRA1B;ADRA2A;MET;ADRA2C;ADRA1D GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A 42609:[DB06314 DB11587] DB06314|SGX-523 MET DB11587|Etafedrine ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007165| signal transduction MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET 42610:[DB06314 DB12555] DB06314|SGX-523 MET DB12555|Nelotanserin HTR2A common genes common pathways GO:0007165| signal transduction HTR2A;MET 42611:[DB06314 DB06469] DB06314|SGX-523 MET DB06469|Lestaurtinib FLT3;CYP3A4 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation MET;FLT3 GO:0016310| phosphorylation FLT3;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT3;MET GO:0006468| protein phosphorylation MET;FLT3 42612:[DB06314 DB06737] DB06314|SGX-523 MET DB06737|Zaltoprofen UGT2B7;CYP2C9;PTGS1 common genes common pathways 42613:[DB06314 DB14583] DB06314|SGX-523 MET DB14583|Segesterone acetate PGR;AR;NR3C1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1;PGR;AR GO:0008283| cell proliferation MET;AR GO:0007165| signal transduction AR;NR3C1;PGR;MET 42614:[DB06314 DB08867] DB06314|SGX-523 MET DB08867|Ulipristal PGR;NR3C1;AR;CYP3A4;CYP1A2;ALB;ORM1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;AR;NR3C1;PGR GO:0008283| cell proliferation MET;AR GO:0007165| signal transduction AR;PGR;NR3C1;MET 42615:[DB06314 DB01251] DB06314|SGX-523 MET DB01251|Gliquidone ABCC8;KCNJ8;CYP2C9 common genes common pathways GO:0007165| signal transduction MET;ABCC8 42616:[DB06314 DB09235] DB06314|SGX-523 MET DB09235|Efonidipine CACNA1I;CACNA1C;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;CACNA1I 42617:[DB06314 DB04725] DB06314|SGX-523 MET DB04725|Licofelone PLA2G2E;PTGS2;ALOX5;CYP2C9;CYP2C8;CYP2J2;UGT1A3 common genes common pathways 42618:[DB06314 DB00153] DB06314|SGX-523 MET DB00153|Ergocalciferol VDR;CYP24A1;CYP27B1;CYP27A1;CYP3A4;CYP2R1 common genes common pathways GO:0007165| signal transduction VDR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;VDR 42619:[DB06314 DB00358] DB06314|SGX-523 MET DB00358|Mefloquine HBA1;ADORA2A;CYP3A4;BCHE;CYP19A1;CYP2D6;ACHE;ABCB1 common genes common pathways GO:0008283| cell proliferation MET;ACHE GO:0007165| signal transduction MET;ADORA2A 42620:[DB06314 DB00770] DB06314|SGX-523 MET DB00770|Alprostadil PTGER2;PTGER1;PTGDR2;ABCC5;SLCO2B1;SLCO3A1;ABCC4;SLCO2A1;SLC22A6 common genes common pathways GO:0007165| signal transduction PTGER1;PTGER2;PTGDR2;MET 42621:[DB06314 DB05956] DB06314|SGX-523 MET DB05956|EVT-101 RXRA;GRIN2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;RXRA GO:0000165| MAPKKK cascade MET;GRIN2B 42622:[DB06314 DB09256] DB06314|SGX-523 MET DB09256|Tegafur TYMS;CYP1A2;CYP2C8;CYP2A6;CYP2E1;CYP3A5 common genes common pathways 42623:[DB06314 DB09229] DB06314|SGX-523 MET DB09229|Aranidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP3A4;ALB;ORM1 common genes common pathways GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1D;ADRA2A;MET;ADRA2C;ADRA1B;ADRA1A;ADRA2B 42624:[DB06314 DB09078] DB06314|SGX-523 MET DB09078|Lenvatinib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FGFR4;KIT;CYP3A4;AOX1;CYP2C8;CYP2C9;CYP1A2;CYP2B6;CYP2C19;CYP2D6;ABCB1;ABCG2;SLC22A6;SLC22A8;SLC22A2;SLCO1B1;ABCB11 common genes common pathways GO:0007165| signal transduction KIT;MET GO:0016310| phosphorylation FLT1;FGFR1;KIT;FLT4;KDR;MET;FGFR3;FGFR2;FGFR4 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT1;KIT;KDR;FLT4;MET GO:0006468| protein phosphorylation MET;FGFR3;FGFR2;FGFR4;FLT1;FGFR1;KIT;FLT4;KDR GO:0000165| MAPKKK cascade FGFR3;MET;FGFR4;FGFR2;FGFR1;KIT GO:0018108| peptidyl-tyrosine phosphorylation KDR;FLT4;KIT;FGFR1;FLT1;FGFR4;FGFR2;FGFR3;MET GO:0046854| phosphatidylinositol phosphorylation FGFR2;FGFR4;MET;FGFR3;FGFR1;KIT GO:0051897| positive regulation of protein kinase B signaling cascade KIT;FGFR1;FGFR2;FGFR4;MET;FGFR3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;MET 42625:[DB06314 DB04974] DB06314|SGX-523 MET DB04974|AP1903 MTOR common genes common pathways GO:0010507| negative regulation of autophagy MTOR;MET GO:0007165| signal transduction MET;MTOR GO:0016310| phosphorylation MTOR;MET GO:0006468| protein phosphorylation MTOR;MET GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;MET 42626:[DB06314 DB00417] DB06314|SGX-523 MET DB00417|Phenoxymethylpenicillin SLC15A1 common genes common pathways 42627:[DB06314 DB11691] DB06314|SGX-523 MET DB11691|Naldemedine OPRM1;OPRD1;OPRK1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;ABCB5 common genes common pathways GO:0007165| signal transduction OPRM1;OPRK1;MET;OPRD1 42628:[DB06314 DB06311] DB06314|SGX-523 MET DB06311|Darapladib PLA2G4A common genes common pathways 42629:[DB06314 DB00701] DB06314|SGX-523 MET DB00701|Amprenavir pol;CYP3A4;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6;CYP3A5;ABCB1;ABCC1;SLCO1B1 common genes common pathways 42630:[DB06314 DB00738] DB06314|SGX-523 MET DB00738|Pentamidine TRDMT1;CYP2C19;CYP1A1;CYP2D6;CYP3A5;CYP4A11;CYP2C8 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 42631:[DB06314 DB00882] DB06314|SGX-523 MET DB00882|Clomifene ESR1;SHBG;CYP11A1;CYP19A1;CYP1A1;CYP1A2;CYP2E1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction MET;ESR1 42632:[DB06314 DB09224] DB06314|SGX-523 MET DB09224|Melperone DRD2;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0007165| signal transduction DRD2;MET 42633:[DB06314 DB01248] DB06314|SGX-523 MET DB01248|Docetaxel TUBB1;BCL2;MAP2;MAP4;MAPT;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP1B1;ABCB1;ABCC10;SLCO1B3;SLC22A7;ABCG2;ABCC2;ABCC1 common genes common pathways GO:0007165| signal transduction NR1I2;MET GO:0008283| cell proliferation MET;BCL2 GO:0010507| negative regulation of autophagy MET;BCL2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET GO:0031116| positive regulation of microtubule polymerization MET;MAPT 42634:[DB06314 DB00172] DB06314|SGX-523 MET DB00172|Proline P4HA2;PRODH;PPIH;PROSC;P4HA1;PPIB;PPIF;PPIC;PPIA;PPIG;P3H1;P5CR2;PARS2;P3H2;P3H3;PYCRL;L3HYPDH;PYCR1;EPRS;SLC6A14;SLC6A7;PYCR2;PRODH;SLC16A10 common genes common pathways 42635:[DB06314 DB00269] DB06314|SGX-523 MET DB00269|Chlorotrianisene ESR1;CYP19A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ESR1 GO:0007165| signal transduction MET;ESR1 42636:[DB06314 DB00497] DB06314|SGX-523 MET DB00497|Oxycodone OPRM1;OPRK1;OPRD1;ORM1;ORM2;CYP2D6;CYP3A4;CYP3A5 common genes common pathways GO:0007165| signal transduction OPRD1;MET;OPRM1;OPRK1 42637:[DB06314 DB12128] DB06314|SGX-523 MET DB12128|Ulimorelin GHSR common genes common pathways GO:0007165| signal transduction GHSR;MET 42638:[DB06314 DB05420] DB06314|SGX-523 MET DB05420|Gallium maltolate RRM1 common genes common pathways 42639:[DB06314 DB08903] DB06314|SGX-523 MET DB08903|Bedaquiline atpE;CYP3A4 common genes common pathways 42640:[DB06314 DB08931] DB06314|SGX-523 MET DB08931|Riociguat GUCY1A2;CYP1A1;CYP3A4;CYP2C8;CYP2J2;ALB;ORM1;ABCG2 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction MET;GUCY1A2 42641:[DB06314 DB01058] DB06314|SGX-523 MET DB01058|Praziquantel CYP3A4;CYP1A2;CYP2C19;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 42642:[DB06314 DB08735] DB06314|SGX-523 MET DB08735|R,S-Warfarin alcohol ALB common genes common pathways 42643:[DB06314 DB00332] DB06314|SGX-523 MET DB00332|Ipratropium CHRM1;CHRM2;CHRM3;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;MET;CHRM3 GO:0008283| cell proliferation CHRM1;MET;CHRM3 42644:[DB06314 DB05025] DB06314|SGX-523 MET DB05025|Arimoclomol SOD1 common genes common pathways 42645:[DB06314 DB06824] DB06314|SGX-523 MET DB06824|Triethylenetetramine GPC1 common genes common pathways 42646:[DB06314 DB06780] DB06314|SGX-523 MET DB06780|Desoxycorticosterone acetate NR3C2;CYP3A4 common genes common pathways GO:0007165| signal transduction NR3C2;MET 42647:[DB06314 DB00991] DB06314|SGX-523 MET DB00991|Oxaprozin PTGS1;PTGS2 common genes common pathways 42648:[DB06314 DB02750] DB06314|SGX-523 MET DB02750|S-(Methylmercury)-L-Cysteine SLC7A5;SLC7A8 common genes common pathways 42649:[DB06314 DB11638] DB06314|SGX-523 MET DB11638|Artenimol ACTG1;ALDH7A1;ANXA2;ATP5L;ATP5O;CAST;CCT3;CFL1;CLIC1;CSRP1;DPYSL2;DSP;EEF1A1;ENO1;FLNA;FTO;G6PD;GAPDHS;GPI;HNRNPA2B1;HNRNPD;HNRNPK;HP1BP3;HSPB1;IQGAP1;KHSRP;LDHA;LDHB;LGALS1;MAP4;MDH1;NPEPPS;PFN1;PGK1;PKM;PPIA;PRDX1;RPL10;RPL14;RPL18;RPL23A;RPL35;RPL4;RPS13;RPS17;RPS18;RPS19;RPS28;RPS5;RPS6;RPS8;RPS9;SF1;SFPQ;SNRPD2;SRP14;SRSF4;TAGLN2;TPI1;TPM1;TUBA1A;VIM;ZYX;HSPA8;TUBB6;TUBB4A;TUBB;ALDOA;GAPDH;CYCS;PGAM1;MYH9;P4HB;DDX5;SHMT2;DDX39B;NPM1;OAT;MDR1;GAPDH;ATP6;HK;ALB;UGT1A9;UGT2B7;CYP2D6;CYP2C19 common genes common pathways GO:0071526| semaphorin-plexin signaling pathway FLNA;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NPM1;HNRNPK;MET;SFPQ GO:2001028| positive regulation of endothelial cell chemotaxis HSPB1;MET GO:0008283| cell proliferation MET;RPL23A;PRDX1 GO:0016310| phosphorylation PKM;MET;PGK1 GO:0051497| negative regulation of stress fiber assembly PFN1;MET GO:0006468| protein phosphorylation CFL1;MET GO:0007165| signal transduction HNRNPK;IQGAP1;MET;LGALS1;ZYX;CLIC1;NPM1;DPYSL2 42650:[DB06314 DB01161] DB06314|SGX-523 MET DB01161|Chloroprocaine SCN10A;GRIN3A;CHRNA10;HTR3A;SLC6A3;BCHE common genes common pathways GO:0007165| signal transduction HTR3A;MET;CHRNA10 42651:[DB06314 DB06216] DB06314|SGX-523 MET DB06216|Asenapine DRD2;HTR2A;HTR1A;HTR1B;HTR2B;HTR2C;HTR5A;HTR6;HTR7;ADRA2A;ADRA2B;ADRA2C;ADRA1A;DRD1;DRD3;DRD4;HRH1;HRH2;ADRB1;ADRB2;CYP1A2;CYP2D6;UGT1A4;CYP3A4 common genes common pathways GO:0007165| signal transduction HTR5A;HTR2C;HTR6;ADRA2A;HRH1;MET;ADRB2;ADRA2C;DRD3;HTR7;HTR1B;DRD2;ADRA1A;ADRA2B;HTR2A;HRH2;DRD4;DRD1;ADRB1;HTR2B;HTR1A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0016310| phosphorylation HTR2B;MET GO:0008283| cell proliferation HTR1A;MET GO:0010507| negative regulation of autophagy HTR2B;ADRA1A;MET GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;ADRB2;MET 42652:[DB06314 DB07374] DB06314|SGX-523 MET DB07374|Anisomycin RPL10L;RPL13A;RPL23;RPL15;RPL19;RPL23A;RSL24D1;RPL26L1;RPL8;RPL37;RPL3;RPL11;SNU13 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;RPL23 GO:0008283| cell proliferation MET;RPL23A 42653:[DB06314 DB14637] DB06314|SGX-523 MET DB14637|Fluprednisolone acetate CYP3A4 common genes common pathways 42654:[DB06314 DB00228] DB06314|SGX-523 MET DB00228|Enflurane GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;GLRB;KCNN4;KCNA1;ATP2C1;GRIA1;CYP2E1;ALB common genes common pathways GO:0007165| signal transduction GABRB1;GABRA6;GABRD;GABRA5;ATP2C1;GABRE;GABRQ;GRIA1;GABRP;GABRB3;MET 42655:[DB06314 DB00663] DB06314|SGX-523 MET DB00663|Flumethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET GO:0007165| signal transduction NR3C1;MET 42656:[DB06314 DB00801] DB06314|SGX-523 MET DB00801|Halazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction MET;GABRB3;GABRQ;GABRE;GABRP;GABRA5;GABRB1;GABRA6;GABRR2;GABRD 42657:[DB06314 DB01282] DB06314|SGX-523 MET DB01282|Carbetocin OXTR common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;OXTR GO:0007165| signal transduction MET;OXTR 42658:[DB06314 DB00477] DB06314|SGX-523 MET DB00477|Chlorpromazine DRD2;DRD1;HTR1A;HTR2A;ADRA1A;ADRA1B;HRH1;KCNH2;DRD1;DRD5;DRD3;DRD4;DRD5;HTR2C;HTR2A;HTR2B;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM3;SMPD1;CALM1;ORM1;ORM2;HTR6;HTR7;HRH4;CYP2D6;CYP1A2;CYP2E1;CYP3A4;BCHE;ALB;ABCB1;ABCB11 common genes common pathways GO:0007165| signal transduction DRD5;CHRM1;HTR7;ADRA1D;DRD3;MET;HRH1;ADRA2C;HRH4;HTR6;HTR2C;ADRA2A;CHRM3;ADRA1B;HTR1A;HTR2B;SMPD1;DRD1;DRD4;ADRA2B;HTR2A;ADRA1A;DRD2 GO:0016310| phosphorylation HTR2B;MET GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0008283| cell proliferation CHRM1;ADRA1D;MET;CHRM3;ADRA1B;HTR1A GO:0010507| negative regulation of autophagy MET;ADRA1A;HTR2B GO:0000165| MAPKKK cascade MET;CALM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD3;DRD2 42659:[DB06314 DB00226] DB06314|SGX-523 MET DB00226|Guanadrel SLC6A2 common genes common pathways 42660:[DB06314 DB01373] DB06314|SGX-523 MET DB01373|Calcium CACNA1C;ATP2C1;TNNC2;TNNC1;SPTBN1;S100B;CAST;COMP;CALM1;AOC1;S100A13;ALPP;S100A8;S100A9;S100A2;CP;BMP4;MGP;PCDH19;PDCD6 common genes common pathways GO:0050918| positive chemotaxis BMP4;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter BMP4;MET GO:0008283| cell proliferation MET;S100B GO:0048754| branching morphogenesis of a tube BMP4;MET GO:0007165| signal transduction MET;ATP2C1 GO:0000165| MAPKKK cascade SPTBN1;CALM1;MET 42661:[DB06314 DB01321] DB06314|SGX-523 MET DB01321|Josamycin rplD;CYP3A4 common genes common pathways 42662:[DB06314 DB00631] DB06314|SGX-523 MET DB00631|Clofarabine POLA1;RRM1;DCK;ABCG2 common genes common pathways GO:0008283| cell proliferation MET;POLA1 GO:0016310| phosphorylation DCK;MET 42663:[DB06314 DB08361] DB06314|SGX-523 MET DB08361|2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide SYK common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;SYK GO:0018108| peptidyl-tyrosine phosphorylation MET;SYK GO:0006468| protein phosphorylation MET;SYK GO:0016310| phosphorylation MET;SYK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway SYK;MET GO:0008283| cell proliferation SYK;MET 42664:[DB06314 DB07159] DB06314|SGX-523 MET DB07159|Tamatinib SYK common genes common pathways GO:0006468| protein phosphorylation SYK;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;SYK GO:0016310| phosphorylation MET;SYK GO:0008283| cell proliferation MET;SYK GO:0018108| peptidyl-tyrosine phosphorylation SYK;MET GO:0007166| cell surface receptor linked signaling pathway SYK;MET 42665:[DB06314 DB09209] DB06314|SGX-523 MET DB09209|Pholcodine OPRM1;OPRK1;OPRD1 common genes common pathways GO:0007165| signal transduction OPRK1;OPRM1;MET;OPRD1 42666:[DB06314 DB00114] DB06314|SGX-523 MET DB00114|Pyridoxal Phosphate AGXT2;GAD1;CBS;KYNU;SHMT1;NFS1;GOT1;OAT;ODC1;AADAT;ABAT;PNPO;SGPL1;TAT;CCBL1;THNSL1;PYGL;SPTLC2;CSAD;HDC;AZIN2;SDS;GCAT;GLDC;GPT;PSAT1;ALAS1;AGXT;PDXP;SPTLC1;CTH;BCAT1;BCAT2;PROSC;FTCD;GOT2;PYGB;PYGM;DDC;GIG18;GAD1;ALAS1;GAD2;DDC;PDXDC1;CCBL2;GADL1;SCLY;IGSF10;PHYKPL;GAD1;SHMT2;ALAS2;GPT2;MOCOS;SDSL;pcap;SRR;SEPSECS;SPTLC3;GAD65;TLH6 common genes common pathways GO:0008283| cell proliferation MET;BCAT1 42667:[DB06314 DB11091] DB06314|SGX-523 MET DB11091|Hydrogen peroxide GPX1;CAT;ALPPL2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;GPX1 GO:0008283| cell proliferation GPX1;MET 42668:[DB06314 DB13179] DB06314|SGX-523 MET DB13179|Troleandomycin rpmF;rplD;NR1I2;CYP3A5;CYP2C9;CYP3A43;CYP2C18;CYP2C8;CYP3A4;CYP3A7;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2 GO:0007165| signal transduction NR1I2;MET 42669:[DB06314 DB01435] DB06314|SGX-523 MET DB01435|Antipyrine PTGS2;PTGS1;CYP2C8;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2A6;CYP2B6;CYP2C18;CYP2D6;CYP2E1;SLC22A6 common genes common pathways 42670:[DB06314 DB11640] DB06314|SGX-523 MET DB11640|Amifampridine KCNA1;NAT1;NAT2 common genes common pathways 42671:[DB06314 DB00898] DB06314|SGX-523 MET DB00898|Ethanol GABRA1;GRIN3A;GLRA1;GLRA2;CACNB1;HTR3A;GABRA2;CHRNA10;CACNA1C;GABRA5;GABRA4;GABRA3;GRIA1;CACNG1;CHRNA2;GABRA6;GRIA2;GRIA4;GRIA3;CHRNA4;CHRNB2;KCNJ3;KCNJ6;VCAM1;SLC29A1;KCNJ5;CHRNA7;CHRNA9;GABRB1;GABRB3;GABRB2;CACNA1S;CACNA1D;CHRNB4;CHRNA3;CHRNA5;CHRNA6;CHRNB3;GABRG1;GABRG3;GABRE;GABRP;GABRQ;GABRD;SLC29A2;HTR3E;HTR3B;HTR3D;HTR3C;CACNG2;KCNJ9;L1CAM;CYP1A1;CYP1A2;CYP2B6;CYP2C9;CYP2C19;CYP2E1;CYP3A4;CYP4A11;ADH1A;ADH1B;ADH1C;ADH5;ADH4;ADH7;ADH6;AKR1A1 common genes common pathways GO:0008283| cell proliferation MET;SLC29A2;CYP1A1 GO:0007165| signal transduction GABRA5;HTR3A;HTR3C;CHRNA2;HTR3B;GABRD;GABRB1;CHRNA6;GABRA6;CHRNA4;CHRNA7;HTR3E;CHRNB2;CHRNB4;CHRNA9;CHRNA3;MET;HTR3D;GRIA2;CHRNA5;GABRB3;GABRP;CHRNA10;GRIA1;GABRQ;GABRE;CHRNB3 42672:[DB06314 DB00197] DB06314|SGX-523 MET DB00197|Troglitazone PPARG;ACSL4;SERPINE1;SLC29A1;ESRRG;ESRRA;PPARD;PPARA;GSTP1;CYP3A4;CYP2C8;UGT1A1;CYP2C19;CYP19A1;CYP1A1;CYP2B6;CYP2C9;CYP3A5;CYP3A7;UGT1A3;UGT1A4;UGT1A6;UGT1A7;UGT1A8;UGT1A9;UGT1A10;UGT2B7;UGT2B15;ABCB11;SLCO1B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRA;ESRRG;SERPINE1;MET;PPARG;PPARA GO:0008283| cell proliferation CYP1A1;PPARD;MET GO:0007165| signal transduction PPARG;MET 42673:[DB06314 DB01186] DB06314|SGX-523 MET DB01186|Pergolide DRD2;DRD3;DRD4;HTR1A;HTR2B;HTR2A;HTR1D;ADRA2B;ADRA2A;ADRA2C;DRD5;DRD1;HTR1B;HTR2C;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;MET;DRD2 GO:0010507| negative regulation of autophagy MET;HTR2B;ADRA1A GO:0008283| cell proliferation HTR1A;ADRA1B;MET;ADRA1D GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0016310| phosphorylation HTR2B;MET GO:0007165| signal transduction ADRA2A;HTR2C;ADRA2C;MET;HTR1B;DRD3;ADRA1D;DRD5;ADRA1A;DRD2;DRD1;ADRA2B;HTR2A;DRD4;HTR2B;ADRA1B;HTR1A;HTR1D 42674:[DB06314 DB00795] DB06314|SGX-523 MET DB00795|Sulfasalazine ALOX5;PTGS2;PTGS1;PPARG;CHUK;IKBKB;SLC7A11;ACAT1;TBXAS1;PLA2G1B;ABCG2;ABCC2;SLC46A1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways GO:0007165| signal transduction PLA2G1B;PPARG;MET GO:0006468| protein phosphorylation IKBKB;MET;CHUK GO:0016310| phosphorylation IKBKB;MET;CHUK GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKB;PLA2G1B;PPARG;CHUK;MET 42675:[DB06314 DB11569] DB06314|SGX-523 MET DB11569|Ixekizumab IL17A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;IL17A 42676:[DB06314 DB01032] DB06314|SGX-523 MET DB01032|Probenecid SLC22A6;SLC22A11;SLC22A8;PANX1;TAS2R16;CYP2C19;CYP2C8;CYP3A4;UGT1A1;ALB;SLC22A2;SLC22A1;ABCC3;ABCC4;ABCC5;SLC16A7;SLC22A5;ABCC6;ABCC1;SLCO1A2;SLC16A1;SLC10A1;SLC22A6;SLC22A10;SLC22A8;ABCC2;ABCC11;SLC22A11;SLCO1C1;SLC22A7;SLC22A12;SLC2A9 common genes common pathways GO:0007165| signal transduction MET;TAS2R16 42677:[DB06314 DB01130] DB06314|SGX-523 MET DB01130|Prednicarbate NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 42678:[DB06314 DB06151] DB06314|SGX-523 MET DB06151|Acetylcysteine GSS;SLC7A11;ACY1;IKBKB;CHUK;GRIN2B;GRIN1;GRIN2A;GRIN2D;GRIN3A;SLCO1B1;SLC22A6 common genes common pathways GO:0000165| MAPKKK cascade GRIN1;GRIN2B;GRIN2A;GRIN2D;MET GO:0006468| protein phosphorylation MET;CHUK;IKBKB GO:0016310| phosphorylation CHUK;MET;IKBKB GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;MET;IKBKB;GRIN1 42679:[DB06314 DB06634] DB06314|SGX-523 MET DB06634|Casopitant CYP3A4;TACR1 common genes common pathways GO:0007165| signal transduction MET;TACR1 42680:[DB06314 DB00628] DB06314|SGX-523 MET DB00628|Clorazepate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRD;GABRA6;GABRB1;GABRA5;GABRP;GABRE;GABRQ;TSPO;MET;GABRB3 GO:0008283| cell proliferation MET;TSPO 42681:[DB06314 DB09089] DB06314|SGX-523 MET DB09089|Trimebutine OPRM1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;KCNMA1;KCNMB1;KCNMB2;KCNMB3;KCNMB4;KCNN4;KCNN1;KCNN2;KCNN3;CACNA1G;CACNA1H;CACNA1I;CHRM1;CHRM2;CHRM3;CHRM4;CYP3A4 common genes common pathways GO:0008283| cell proliferation CHRM1;CHRM4;MET;CHRM3 GO:0007165| signal transduction CHRM4;CHRM1;OPRM1;CHRM3;CACNA1I;CHRM2;MET GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 42682:[DB06314 DB09570] DB06314|SGX-523 MET DB09570|Ixazomib CYP3A4;CYP1A2;CYP2B6;CYP2C8;CYP2D6;CYP2C19;CYP2C9 common genes common pathways 42683:[DB06314 DB08815] DB06314|SGX-523 MET DB08815|Lurasidone DRD2;HTR2A;HTR7;HTR1A;ADRA2C;ADRA2A;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0008283| cell proliferation MET;HTR1A GO:0007165| signal transduction DRD2;HTR2A;HTR1A;ADRA2A;ADRA2C;MET;HTR7 42684:[DB06314 DB00400] DB06314|SGX-523 MET DB00400|Griseofulvin KRT12;CYP1A2;CYP3A4;CYP2D6 common genes common pathways 42685:[DB06314 DB01629] DB06314|SGX-523 MET DB01629|5-Fluorouridine SOD1 common genes common pathways 42686:[DB06314 DB12478] DB06314|SGX-523 MET DB12478|Piribedil DRD2;DRD3 common genes common pathways GO:0007165| signal transduction DRD2;MET;DRD3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD3;DRD2 42687:[DB06314 DB00468] DB06314|SGX-523 MET DB00468|Quinine GP9;KCNN4;CYP3A5;CYP1A2;CYP2C8;CYP2C9;CYP2C19;CYP2E1;CYP3A7;CYP1A1;CYP3A4;CYP2D6;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A4;SLCO1B1 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 42688:[DB06314 DB00208] DB06314|SGX-523 MET DB00208|Ticlopidine P2RY12;CYP2C19;CYP2D6;CYP3A4;MPO;CYP2C9;CYP2C8;CYP1A2;CYP1A1;CYP2B6;CYP2E1 common genes common pathways GO:0007165| signal transduction MET;P2RY12 GO:0008283| cell proliferation CYP1A1;MET 42689:[DB06314 DB01021] DB06314|SGX-523 MET DB01021|Trichlormethiazide SLC12A3;ATP1A1;CA1;CA2;CA4;TPMT common genes common pathways 42690:[DB06314 DB00824] DB06314|SGX-523 MET DB00824|Enprofylline PDE4A;PDE4B;ADORA2B;ADORA1;ADORA2A;ADORA3 common genes common pathways GO:0007165| signal transduction ADORA3;ADORA2B;ADORA2A;PDE4B;MET;PDE4A;ADORA1 42691:[DB06314 DB11834] DB06314|SGX-523 MET DB11834|Guselkumab IL23A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;IL23A 42692:[DB06314 DB08906] DB06314|SGX-523 MET DB08906|Fluticasone furoate NR3C1;CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0007165| signal transduction NR3C1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 42693:[DB06314 DB02546] DB06314|SGX-523 MET DB02546|Vorinostat HDAC1;HDAC2;HDAC3;HDAC6;HDAC8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC1;HDAC2;MET;HDAC3 42694:[DB06314 DB11124] DB06314|SGX-523 MET DB11124|Racepinephrine ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRA1D;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation ADRA1B;ADRA1D;MET GO:0007165| signal transduction ADRA2A;ADRB2;ADRA2C;MET;ADRA1D;ADRB3;ADRA1A;ADRA2B;ADRB1;ADRA1B GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET 42695:[DB06314 DB01096] DB06314|SGX-523 MET DB01096|Oxamniquine CYP2D6 common genes common pathways 42696:[DB06314 DB06587] DB06314|SGX-523 MET DB06587|Mitemcinal MLNR;CYP3A4 common genes common pathways GO:0007165| signal transduction MLNR;MET 42697:[DB06314 DB07402] DB06314|SGX-523 MET DB07402|Azapropazone ALB common genes common pathways 42698:[DB06314 DB02209] DB06314|SGX-523 MET DB02209|Pyridoxine phosphate pdxJ;ODC1;PNPO common genes common pathways 42699:[DB06314 DB05749] DB06314|SGX-523 MET DB05749|MPI-674 CYP19A1 common genes common pathways 42700:[DB06314 DB09363] DB06314|SGX-523 MET DB09363|Rauwolfia serpentina root SLC18A2;MAOA;MAOB;SLC6A2;VMAT2 common genes common pathways 42701:[DB06314 DB00912] DB06314|SGX-523 MET DB00912|Repaglinide ABCC8;PPARG;CYP3A4;CYP2C8;ALB;SLCO1B1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;MET GO:0007165| signal transduction ABCC8;PPARG;MET 42702:[DB06314 DB04888] DB06314|SGX-523 MET DB04888|Bifeprunox DRD2;HTR1A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0007165| signal transduction MET;HTR1A;DRD2 GO:0008283| cell proliferation HTR1A;MET 42703:[DB06314 DB14010] DB06314|SGX-523 MET DB14010|5-methoxy-N,N-dimethyltryptamine HTR1A;HTR2A;CYP2D6 common genes common pathways GO:0008283| cell proliferation MET;HTR1A GO:0007165| signal transduction MET;HTR1A;HTR2A 42704:[DB06314 DB01256] DB06314|SGX-523 MET DB01256|Retapamulin rplC;CYP3A4 common genes common pathways 42705:[DB06314 DB14509] DB06314|SGX-523 MET DB14509|Lithium carbonate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation MET;IMPA1;IMPA2 GO:0007165| signal transduction IMPA1;MET;IMPA2 GO:0016310| phosphorylation MET;GSK3B GO:0006468| protein phosphorylation GSK3B;MET 42706:[DB06314 DB04836] DB06314|SGX-523 MET DB04836|Amineptine SLC6A2;SLC6A4 common genes common pathways 42707:[DB06314 DB00211] DB06314|SGX-523 MET DB00211|Midodrine ADRA1A;ADRA1B;ADRA1D;CYP2D6;SLC15A1 common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction MET;ADRA1D;ADRA1A;ADRA1B GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1B;ADRA1D;MET 42708:[DB06314 DB08895] DB06314|SGX-523 MET DB08895|Tofacitinib JAK1;JAK2;JAK3;TYK2;CYP3A4;CYP2C19;ALB common genes common pathways GO:0007165| signal transduction MET;JAK2 GO:0006468| protein phosphorylation TYK2;JAK2;JAK3;JAK1;MET GO:0016310| phosphorylation MET;JAK1;JAK3;JAK2;TYK2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway TYK2;MET;JAK1 GO:0000165| MAPKKK cascade JAK3;JAK2;MET;JAK1 GO:0018108| peptidyl-tyrosine phosphorylation JAK3;JAK2;MET 42709:[DB06314 DB01324] DB06314|SGX-523 MET DB01324|Polythiazide SLC12A3 common genes common pathways 42710:[DB06314 DB14539] DB06314|SGX-523 MET DB14539|Hydrocortisone acetate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ANXA1;MET GO:0007165| signal transduction NR3C1;ANXA1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 42711:[DB06314 DB00863] DB06314|SGX-523 MET DB00863|Ranitidine HRH2;ACHE;BCHE;CYP1A2;CYP2C19;CYP2D6;CYP3A4;CYP3A5;SLC22A1;ABCB1;SLC22A8;SLC22A2;SLC22A6 common genes common pathways GO:0008283| cell proliferation MET;ACHE GO:0007165| signal transduction MET;HRH2 42712:[DB06314 DB05885] DB06314|SGX-523 MET DB05885|Seletracetam SV2A;CACNA1B;GLRA1;GLRB;CYP3A4 common genes common pathways 42713:[DB06314 DB11127] DB06314|SGX-523 MET DB11127|Selenious acid GPX1;TXNRD1;SEPP1 common genes common pathways GO:0007165| signal transduction MET;TXNRD1 GO:0008283| cell proliferation MET;TXNRD1;GPX1 GO:0051897| positive regulation of protein kinase B signaling cascade GPX1;MET 42714:[DB06314 DB09204] DB06314|SGX-523 MET DB09204|Arotinolol ADRB1;ADRB2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;ALB;ORM1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction MET;ADRB2;ADRA1D;ADRA1A;ADRB1;ADRA1B GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0010507| negative regulation of autophagy MET;ADRA1A 42715:[DB06314 DB08826] DB06314|SGX-523 MET DB08826|Deferiprone UGT1A6 common genes common pathways 42716:[DB06314 DB01205] DB06314|SGX-523 MET DB01205|Flumazenil GABRA1;GABRG2;GABRA5;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRA5;GABRA6;GABRB1;GABRD;GABRB3;MET;GABRE;GABRQ;GABRP 42717:[DB06314 DB09185] DB06314|SGX-523 MET DB09185|Viloxazine SLC6A2;CYP1A2 common genes common pathways 42718:[DB06314 DB00285] DB06314|SGX-523 MET DB00285|Venlafaxine SLC6A4;SLC6A2;SLC6A3;CYP2D6;CYP3A4;CYP2C9;CYP2C19;CYP2B6;ABCB1;ABCG2 common genes common pathways 42719:[DB06314 DB06013] DB06314|SGX-523 MET DB06013|Aldoxorubicin TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 42720:[DB06314 DB05968] DB06314|SGX-523 MET DB05968|PR-104 TNF common genes common pathways GO:0000165| MAPKKK cascade MET;TNF GO:0051897| positive regulation of protein kinase B signaling cascade TNF;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNF 42721:[DB06314 DB14004] DB06314|SGX-523 MET DB14004|Tildrakizumab IL12B;IL23A;CYP4A11 common genes common pathways GO:0008283| cell proliferation MET;IL12B GO:0007166| cell surface receptor linked signaling pathway IL12B;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;IL23A 42722:[DB06314 DB00708] DB06314|SGX-523 MET DB00708|Sufentanil OPRM1;OPRD1;OPRK1;CYP3A4 common genes common pathways GO:0007165| signal transduction OPRM1;OPRK1;MET;OPRD1 42723:[DB06314 DB09148] DB06314|SGX-523 MET DB09148|Florbetaben (18F) APP;CYP2J2;CYP4F2 common genes common pathways GO:0006468| protein phosphorylation APP;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter APP;MET GO:0051897| positive regulation of protein kinase B signaling cascade APP;MET GO:0050918| positive chemotaxis APP;MET 42724:[DB06314 DB00390] DB06314|SGX-523 MET DB00390|Digoxin ATP1A1;CYP11A1;CYP3A4;ABCB1;SLCO4C1;SLC22A8;SLCO2B1;ABCB11;SLCO1A2;SLC51A;SLC51B;SLCO4A1;SLCO1B3;SLCO1C1;SLCO1B1 common genes common pathways 42725:[DB06314 DB00407] DB06314|SGX-523 MET DB00407|Ardeparin SERPINC1;SERPIND1 common genes common pathways 42726:[DB06314 DB00822] DB06314|SGX-523 MET DB00822|Disulfiram ALDH2;DBH;CYP2E1;CYP3A4;CYP3A5;ABCB11 common genes common pathways 42727:[DB06314 DB00966] DB06314|SGX-523 MET DB00966|Telmisartan AGTR1;PPARG;CYP2C19;UGT1A3;ABCB1;ABCC2;ABCG2;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;MET GO:0007165| signal transduction AGTR1;MET;PPARG 42728:[DB06314 DB05014] DB06314|SGX-523 MET DB05014|XL999 FGFR3;FGFR1;KDR;FLT3;PDGFRB;RET common genes common pathways GO:0046854| phosphatidylinositol phosphorylation FGFR1;PDGFRB;MET;FGFR3 GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRB;FGFR3;MET;FGFR1 GO:0007165| signal transduction RET;PDGFRB;MET GO:0016310| phosphorylation PDGFRB;FLT3;MET;FGFR3;FGFR1;KDR;RET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway RET;KDR;MET;FLT3;PDGFRB GO:0006468| protein phosphorylation FGFR1;KDR;RET;PDGFRB;MET;FLT3;FGFR3 GO:0018108| peptidyl-tyrosine phosphorylation MET;FLT3;FGFR3;PDGFRB;RET;FGFR1;KDR GO:0000165| MAPKKK cascade FGFR3;MET;PDGFRB;RET;FGFR1 42729:[DB06314 DB09378] DB06314|SGX-523 MET DB09378|Fluprednisolone CYP3A4 common genes common pathways 42730:[DB06314 DB12026] DB06314|SGX-523 MET DB12026|Voxilaprevir CYP3A4;CYP1A2;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 42731:[DB06314 DB00215] DB06314|SGX-523 MET DB00215|Citalopram SLC6A4;HRH1;ADRA1A;CHRM1;HTR2C;CYP3A4;CYP2C19;CYP2D6;CYP2E1;CYP1A2;CYP2B6;ABCB1;SLC6A3;SLC6A2;SLC6A4 common genes common pathways GO:0008283| cell proliferation CHRM1;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0007165| signal transduction CHRM1;HTR2C;MET;HRH1;ADRA1A GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A 42732:[DB06314 DB00250] DB06314|SGX-523 MET DB00250|Dapsone CYP3A5;CYP3A4;FMO3;PTGS1;PTGS2;CYP2C8;CYP2C19;NAT2;CYP2C9;CYP3A7;CYP2E1;MPO;CYP2C18 common genes common pathways 42733:[DB06314 DB00980] DB06314|SGX-523 MET DB00980|Ramelteon MTNR1A;MTNR1B;CYP1A2;CYP2C19;CYP3A4;CYP2C9 common genes common pathways GO:0007165| signal transduction MTNR1A;MET;MTNR1B 42734:[DB06314 DB00241] DB06314|SGX-523 MET DB00241|Butalbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRA6;GABRB1;CHRNA7;CHRNA4;GABRD;GABRA5;GABRQ;GABRE;GABRP;MET;GABRB3;GRIA2 42735:[DB06314 DB00467] DB06314|SGX-523 MET DB00467|Enoxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 42736:[DB06314 DB08837] DB06314|SGX-523 MET DB08837|Tetraethylammonium CHRNA9;KCNA1;SLC22A1;SLC22A2;SLC22A3;SLC22A4;SLC22A5;SLC22A8;SLC47A1 common genes common pathways GO:0007165| signal transduction CHRNA9;MET 42737:[DB06314 DB03336] DB06314|SGX-523 MET DB03336|BIA COMT common genes common pathways 42738:[DB06314 DB12693] DB06314|SGX-523 MET DB12693|Ritanserin HTR2A;CYP2D6 common genes common pathways GO:0007165| signal transduction HTR2A;MET 42739:[DB06314 DB09124] DB06314|SGX-523 MET DB09124|Medrogestone PGR;CYP3A4;ALB;SHBG;SERPINA6 common genes common pathways GO:0007165| signal transduction PGR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PGR 42740:[DB06314 DB00013] DB06314|SGX-523 MET DB00013|Urokinase PLG;PLAUR;PLAU;PLAT;SERPINE1;SERPINB2;SERPINA5;LRP2;ST14;NID1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;SERPINE1 GO:0008283| cell proliferation LRP2;MET GO:0007165| signal transduction PLAUR;MET;PLAU 42741:[DB06314 DB00206] DB06314|SGX-523 MET DB00206|Reserpine SLC18A2;SLC18A1;BIRC5;CYP3A5;ABCB1;SLC22A1;ABCB11;ABCC2;SLC22A2;SLCO1B1;SLCO2B1 common genes common pathways GO:0006468| protein phosphorylation MET;BIRC5 42742:[DB06314 DB01222] DB06314|SGX-523 MET DB01222|Budesonide NR3C1;CYP3A4;CYP3A5;ABCB11 common genes common pathways GO:0007165| signal transduction NR3C1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 42743:[DB06314 DB06446] DB06314|SGX-523 MET DB06446|Dotarizine HTR2A;HTR1A;CACNA1A;HTR2C;CYP3A4 common genes common pathways GO:0008283| cell proliferation MET;HTR1A GO:0007165| signal transduction HTR1A;HTR2A;MET;HTR2C 42744:[DB06314 DB09383] DB06314|SGX-523 MET DB09383|Meprednisone CYP3A4;ALB common genes common pathways 42745:[DB06314 DB01403] DB06314|SGX-523 MET DB01403|Methotrimeprazine DRD2;DRD1;DRD5;DRD3;DRD4;HTR2A;HTR2C;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2E1 common genes common pathways GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1B;CHRM1;ADRA1D;CHRM4;CHRM5;MET;CHRM3 GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction DRD3;ADRA1D;CHRM4;CHRM1;DRD5;CHRM3;HTR2C;ADRA2A;CHRM2;ADRA2C;HRH1;CHRM5;MET;ADRA1B;ADRA1A;DRD2;ADRA2B;HTR2A;DRD4;DRD1 GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET;DRD3 42746:[DB06314 DB14009] DB06314|SGX-523 MET DB14009|Medical Cannabis CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway TRPA1;MET;TRPV1 GO:0008283| cell proliferation MET;GPX1;CYP1A1;HTR1A GO:0007165| signal transduction PLA2G1B;PPARG;OPRM1;CNR1;CACNA1I;MET;GPR12;SMPD1;GPR18;CHRNA7;OPRD1;GPR55;HTR1A;CNR2;HTR2A GO:0051897| positive regulation of protein kinase B signaling cascade MET;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;PLA2G1B;MET 42747:[DB06314 DB00137] DB06314|SGX-523 MET DB00137|Lutein ALB common genes common pathways 42748:[DB06314 DB08954] DB06314|SGX-523 MET DB08954|Ifenprodil GRIN1;GRIN2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;GRIN1 GO:0000165| MAPKKK cascade MET;GRIN2B;GRIN1 42749:[DB06314 DB11338] DB06314|SGX-523 MET DB11338|Clove oil VCAM1;CXCL10;COL1A1;CSF2RA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;CXCL10 GO:0007166| cell surface receptor linked signaling pathway MET;CXCL10 GO:0018108| peptidyl-tyrosine phosphorylation CSF2RA;MET GO:0000165| MAPKKK cascade MET;CSF2RA GO:0007165| signal transduction CXCL10;MET 42750:[DB06314 DB00505] DB06314|SGX-523 MET DB00505|Tridihexethyl CHRM3;CHRM1;CHRM2 common genes common pathways GO:0007165| signal transduction MET;CHRM2;CHRM3;CHRM1 GO:0008283| cell proliferation CHRM1;MET;CHRM3 42751:[DB06314 DB00166] DB06314|SGX-523 MET DB00166|Lipoic Acid LIPT1;LIAS;SLC5A6;POR common genes common pathways 42752:[DB06314 DB11635] DB06314|SGX-523 MET DB11635|Tocofersolan ABCB1;CYP4F2;CYP3A4;TTPA;SCARB1;NPC1L1;ABCG5;ABCG8;ABCA1;SEC14L4;SEC14L2;SEC14L3;APOBR common genes common pathways 42753:[DB06314 DB00837] DB06314|SGX-523 MET DB00837|Progabide GABBR1;GABRA1 common genes common pathways GO:0007165| signal transduction MET;GABBR1 42754:[DB06314 DB06785] DB06314|SGX-523 MET DB06785|Ganirelix GNRHR common genes common pathways GO:0007165| signal transduction GNRHR;MET 42755:[DB06314 DB13620] DB06314|SGX-523 MET DB13620|Potassium gluconate FXYD2;ATP1A1;SLC12A1;ATP4A;ATP4B common genes common pathways 42756:[DB06314 DB14071] DB06314|SGX-523 MET DB14071|Desmethylsertraline ABCB1 common genes common pathways 42757:[DB06314 DB00381] DB06314|SGX-523 MET DB00381|Amlodipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA1B;CACNA2D3;CACNB1;CA1;SMPD1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP2B6;CYP2A6;CYP2C8;CYP2C9;CYP2D6;ABCB1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction SMPD1;MET 42758:[DB06314 DB01173] DB06314|SGX-523 MET DB01173|Orphenadrine GRIN2D;GRIN1;GRIN3B;GRIN3A;HRH1;SLC6A2;SCN10A;CYP2B6;CYP3A4;CYP2E1;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;GRIN1 GO:0007165| signal transduction MET;HRH1 GO:0000165| MAPKKK cascade GRIN1;MET;GRIN2D 42759:[DB06314 DB00915] DB06314|SGX-523 MET DB00915|Amantadine GRIN3A;CHRNA7;DRD2;CHRNA4;CHRNA3;DDC;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0007165| signal transduction CHRNA7;CHRNA4;DRD2;MET;CHRNA3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET 42760:[DB06314 DB06706] DB06314|SGX-523 MET DB06706|Isometheptene ADRA1A;SLC18A2 common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1A;MET GO:0010507| negative regulation of autophagy ADRA1A;MET 42761:[DB06314 DB00238] DB06314|SGX-523 MET DB00238|Nevirapine pol;CYP2B6;CYP3A4;CYP3A5;CYP2C9;CYP2A6;CYP2D6;CYP1A2;ALB;SLC22A1 common genes common pathways 42762:[DB06314 DB00214] DB06314|SGX-523 MET DB00214|Torasemide SLC12A1;CYP2C8;CYP2C9;PTGS1 common genes common pathways 42763:[DB06314 DB11792] DB06314|SGX-523 MET DB11792|Mirodenafil CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 42764:[DB06314 DB03856] DB06314|SGX-523 MET DB03856|L-Eflornithine ODC1 common genes common pathways 42765:[DB06314 DB01120] DB06314|SGX-523 MET DB01120|Gliclazide ABCC8;VEGFA;CYP2C9;CYP2C19;ALB common genes common pathways GO:0007165| signal transduction MET;ABCC8 GO:0048754| branching morphogenesis of a tube VEGFA;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;VEGFA GO:0050918| positive chemotaxis VEGFA;MET 42766:[DB06314 DB07339] DB06314|SGX-523 MET DB07339|(3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione NQO2 common genes common pathways 42767:[DB06314 DB04956] DB06314|SGX-523 MET DB04956|Afelimomab TNF common genes common pathways GO:0000165| MAPKKK cascade TNF;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNF GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF 42768:[DB06314 DB00423] DB06314|SGX-523 MET DB00423|Methocarbamol CA1 common genes common pathways 42769:[DB06314 DB06726] DB06314|SGX-523 MET DB06726|Bufuralol ADRB1;ADRB2;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007165| signal transduction ADRB1;ADRB3;ADRB2;MET GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 42770:[DB06314 DB11477] DB06314|SGX-523 MET DB11477|Xylazine ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0007165| signal transduction ADRA2B;ADRA2C;MET;ADRA2A 42771:[DB06314 DB00244] DB06314|SGX-523 MET DB00244|Mesalazine PTGS2;PTGS1;ALOX5;PPARG;CHUK;IKBKB;MPO common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IKBKB;MET;CHUK;PPARG GO:0007165| signal transduction PPARG;MET GO:0006468| protein phosphorylation IKBKB;MET;CHUK GO:0016310| phosphorylation IKBKB;MET;CHUK 42772:[DB06314 DB11274] DB06314|SGX-523 MET DB11274|Dihydro-alpha-ergocryptine DRD2;DRD1;DRD5;DRD3;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;MET;DRD2 GO:0007165| signal transduction DRD5;DRD3;MET;DRD1;DRD2 42773:[DB06314 DB00274] DB06314|SGX-523 MET DB00274|Cefmetazole mrcA;ALB;SLC15A1;SLC15A2 common genes common pathways 42774:[DB06314 DB01352] DB06314|SGX-523 MET DB01352|Aprobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRA5;CHRNA4;CHRNA7;GABRA6;GRIA2;MET 42775:[DB06314 DB06468] DB06314|SGX-523 MET DB06468|Cariporide SLC9A1;MPO common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter SLC9A1;MET 42776:[DB06314 DB14185] DB06314|SGX-523 MET DB14185|Aripiprazole lauroxil DRD2;HTR1A;HTR2A;HTR1B;HTR1D;HTR1E;DRD1;DRD5;DRD3;DRD4;HTR2C;HTR3A;HTR6;HTR7;HRH1;ADRA1A;ADRA1B;ADRA2A;ADRA2B;ADRA2C;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP3A5;CYP3A7;ALB common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0007165| signal transduction CHRM1;DRD5;HTR1E;DRD3;HTR7;CHRM4;HTR1B;HRH1;MET;CHRM5;CHRM2;ADRA2C;CHRM3;HTR6;HTR2C;ADRA2A;HTR1D;HTR1A;ADRA1B;HTR2A;ADRA2B;DRD4;DRD1;HTR3A;ADRA1A;DRD2 GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation CHRM3;MET;CHRM5;CHRM4;CHRM1;ADRA1B;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET 42777:[DB06314 DB01044] DB06314|SGX-523 MET DB01044|Gatifloxacin gyrA;gyrB;parC;parE;CYP1A2;ALB common genes common pathways 42778:[DB06314 DB00759] DB06314|SGX-523 MET DB00759|Tetracycline rpsG;rpsN;rpsC;rpsH;rpsS;PRNP;PADI4;CYP3A4;ALB;SLC22A6;SLC22A8;SLC22A11;SLC22A7;SLCO2B1 common genes common pathways 42779:[DB06314 DB04894] DB06314|SGX-523 MET DB04894|Vapreotide SSTR2;SSTR5;TACR1;CYP3A4 common genes common pathways GO:0007165| signal transduction SSTR2;SSTR5;MET;TACR1 42780:[DB06314 DB01206] DB06314|SGX-523 MET DB01206|Lomustine STMN4;CYP3A4;CYP2D6 common genes common pathways 42781:[DB06314 DB09079] DB06314|SGX-523 MET DB09079|Nintedanib FLT1;KDR;FLT4;FGFR1;FGFR2;FGFR3;FLT3;LCK;LYN;SRC;CYP3A4;ABCB1 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation FGFR2;LYN;FGFR3;FLT3;MET;LCK;KDR;FLT4;FGFR1;SRC;FLT1 GO:0035635| entry of bacterium into host cell SRC;MET GO:0000165| MAPKKK cascade FGFR3;MET;FGFR2;FGFR1 GO:0016310| phosphorylation FLT1;SRC;FLT4;LCK;KDR;FGFR1;LYN;FGFR3;FLT3;MET;FGFR2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT3;MET;LYN;LCK;KDR;FLT4;FLT1 GO:0006468| protein phosphorylation FGFR2;FLT3;MET;LYN;FGFR3;FGFR1;FLT4;LCK;KDR;FLT1;SRC GO:0007165| signal transduction SRC;LYN;MET GO:0008283| cell proliferation MET;SRC GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGFR2;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;FGFR3;FGFR2;SRC;FGFR1;LCK GO:0046854| phosphatidylinositol phosphorylation FGFR1;LCK;MET;FGFR3;FGFR2 42782:[DB06314 DB12001] DB06314|SGX-523 MET DB12001|Abemaciclib CDK4;CDK6;CYP3A4;ALB;ORM1;ORM2;SLC47A1;SLC47A2;OTC;ABCB1;ABCG2 common genes common pathways GO:0006468| protein phosphorylation MET;CDK4;CDK6 GO:0016310| phosphorylation CDK4;CDK6;MET GO:0007165| signal transduction MET;CDK4;CDK6 42783:[DB06314 DB07525] DB06314|SGX-523 MET DB07525|3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine FGFR1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;FGFR1 GO:0046854| phosphatidylinositol phosphorylation MET;FGFR1 GO:0000165| MAPKKK cascade FGFR1;MET GO:0018108| peptidyl-tyrosine phosphorylation FGFR1;MET GO:0016310| phosphorylation FGFR1;MET GO:0006468| protein phosphorylation MET;FGFR1 42784:[DB06314 DB08953] DB06314|SGX-523 MET DB08953|Indalpine CYP3A4 common genes common pathways 42785:[DB06314 DB01131] DB06314|SGX-523 MET DB01131|Proguanil DHFR;CYP2C19;CYP2D6;CYP2C9;CYP2E1;CYP3A4 common genes common pathways 42786:[DB06314 DB00421] DB06314|SGX-523 MET DB00421|Spironolactone NR3C2;AR;PGR;NR3C1;CYP11B2;SRD5A1;SRD5A2;SRD5A3;SHBG;CACNG1;CACNA2D1;CACNA2D2;CACNA2D3;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1B;CACNA1A;CACNA1G;CACNA1H;CACNA1I;NR1I2;CYP2C8;CYP11B1;ABCC2;ABCB1;SLCO1A2;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;NR3C1;AR;NR1I2;MET GO:0007165| signal transduction AR;NR3C2;PGR;NR3C1;CACNA1I;NR1I2;MET GO:0008283| cell proliferation MET;AR 42787:[DB06314 DB00572] DB06314|SGX-523 MET DB00572|Atropine CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;GLRA1;CHRNA4;CHRNB2;ABCB11 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0008283| cell proliferation CHRM3;CHRM5;MET;CHRM4;CHRM1 GO:0007165| signal transduction CHRNA4;CHRM3;CHRNB2;CHRM2;CHRM5;MET;CHRM4;CHRM1 42788:[DB06314 DB01045] DB06314|SGX-523 MET DB01045|Rifampicin rpoB;rpoC;NR1I2;SLCO1B1;SLCO1A2;SLCO1B3;CYP51A1;ALB;SLCO2B1;CYP2C9;CYP1A2;CYP2C8;CYP3A4;CYP2B6;UGT1A1;CYP2C19;CYP2A6;CYP2E1;CYP3A43;CYP3A7;CYP4A11;CYP2D6;ABCB1;SLCO1B3;ABCC1;SLCO2B1;ABCB11;SLCO1A2;SLC22A7;SLCO1B1;ABCC5;ABCC2;ABCC3;SLC22A6;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2 GO:0007165| signal transduction NR1I2;MET 42789:[DB06314 DB05339] DB06314|SGX-523 MET DB05339|MN-305 HTR1A common genes common pathways GO:0007165| signal transduction HTR1A;MET GO:0008283| cell proliferation MET;HTR1A 42790:[DB06314 DB00415] DB06314|SGX-523 MET DB00415|Ampicillin SLC15A1;SLC15A2;TEK;ALB;SLC22A5;SLC15A1;SLC15A2;SLC16A1 common genes common pathways GO:0007165| signal transduction MET;TEK GO:0006468| protein phosphorylation MET;TEK GO:0016310| phosphorylation TEK;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway TEK;MET GO:0000165| MAPKKK cascade MET;TEK GO:0018108| peptidyl-tyrosine phosphorylation TEK;MET GO:0051897| positive regulation of protein kinase B signaling cascade TEK;MET 42791:[DB06314 DB00110] DB06314|SGX-523 MET DB00110|Palivizumab FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction FCGR1A;MET;FCGR2B;FCGR2C 42792:[DB06314 DB00312] DB06314|SGX-523 MET DB00312|Pentobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP3A4;CYP2C19;CYP2A6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NR1I2;MET GO:0007165| signal transduction CHRNA7;CHRNA4;GABRA6;GABRB1;GABRD;GABRA5;GABRQ;GABRE;GABRP;GABRB3;GRIA2;MET;NR1I2 GO:0000165| MAPKKK cascade MET;GRIN2D;GRIN2B;GRIN2A;GRIN1;GRIN2C 42793:[DB06314 DB01094] DB06314|SGX-523 MET DB01094|Hesperetin SOAT1;SOAT2;MTTP;SHBG;CYP1A2;ABCG2 common genes common pathways 42794:[DB06314 DB05139] DB06314|SGX-523 MET DB05139|CR002 PDGFD common genes common pathways 42795:[DB06314 DB11275] DB06314|SGX-523 MET DB11275|Epicriptine DRD1;DRD5;DRD2;DRD3;DRD4 common genes common pathways GO:0007165| signal transduction DRD3;DRD5;MET;DRD2;DRD4;DRD1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET;DRD3 42796:[DB06314 DB00650] DB06314|SGX-523 MET DB00650|Leucovorin SLC22A8 common genes common pathways 42797:[DB06314 DB08980] DB06314|SGX-523 MET DB08980|Fendiline CYP3A4 common genes common pathways 42798:[DB06314 DB09183] DB06314|SGX-523 MET DB09183|Dasabuvir CYP2C8;CYP3A4;CYP2D6;ABCG2;ABCB5;ABCB1 common genes common pathways 42799:[DB06314 DB00111] DB06314|SGX-523 MET DB00111|Daclizumab IL2RA;IL2RB;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0000165| MAPKKK cascade IL2RB;IL2RA;MET GO:0007166| cell surface receptor linked signaling pathway MET;IL2RA GO:0008283| cell proliferation IL2RA;MET GO:0007165| signal transduction FCGR1A;MET;IL2RB;FCGR2B;FCGR2C 42800:[DB06314 DB01030] DB06314|SGX-523 MET DB01030|Topotecan TOP1;TOP1MT;CYP3A4;ABCG2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0016310| phosphorylation TOP1;MET 42801:[DB06314 DB13933] DB06314|SGX-523 MET DB13933|Nonacog beta pegol F7;F8;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;F7;MET 42802:[DB06314 DB13948] DB06314|SGX-523 MET DB13948|N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine HTR2A common genes common pathways GO:0007165| signal transduction HTR2A;MET 42803:[DB06314 DB01466] DB06314|SGX-523 MET DB01466|Ethylmorphine OPRM1;CYP2D6;POR;CYP2B6;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;OPRM1 42804:[DB06314 DB00568] DB06314|SGX-523 MET DB00568|Cinnarizine HRH1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNA1G;CACNA1H;CACNA1I;DRD2;DRD1;DRD5;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP1A2;CYP2B6;CYP2A6;CYP1A1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0007165| signal transduction DRD2;DRD1;CHRM4;DRD5;CHRM1;CACNA1I;CHRM3;HRH1;CHRM5;MET;CHRM2 GO:0008283| cell proliferation CHRM4;CHRM1;CHRM3;CHRM5;MET;CYP1A1 42805:[DB06314 DB07768] DB06314|SGX-523 MET DB07768|Epitestosterone AKR1C1;AKR1C2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;AKR1C2 42806:[DB06314 DB05482] DB06314|SGX-523 MET DB05482|7-ethyl-10-hydroxycamptothecin TOP1;CYP3A4 common genes common pathways GO:0016310| phosphorylation TOP1;MET 42807:[DB06314 DB01053] DB06314|SGX-523 MET DB01053|Benzylpenicillin bla;SLC22A8;SLC15A1;SLC15A2;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A4;SLC22A11;SLCO2B1;SLCO4A1;SLCO3A1;SLCO1B1 common genes common pathways 42808:[DB06314 DB03907] DB06314|SGX-523 MET DB03907|N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide COMT common genes common pathways 42809:[DB06314 DB01085] DB06314|SGX-523 MET DB01085|Pilocarpine CHRM3;CHRM1;CHRM2;CHRM4;CYP2A6;CYP2E1;CYP3A4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0007165| signal transduction CHRM3;MET;CHRM2;CHRM4;CHRM1 GO:0008283| cell proliferation CHRM1;CHRM4;MET;CHRM3 42810:[DB06314 DB12773] DB06314|SGX-523 MET DB12773|Sifalimumab IFNA2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway IFNA2;MET 42811:[DB06314 DB00227] DB06314|SGX-523 MET DB00227|Lovastatin HMGCR;ITGAL;HDAC2;CYP3A4;CYP3A5;CYP3A7;PON3;CYP2C8;CYP2C9;CYP2D6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC2;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;HDAC2 GO:0007165| signal transduction ITGAL;MET 42812:[DB06314 DB01645] DB06314|SGX-523 MET DB01645|Genistein ESR2;TOP2A;PTK2B;NCOA1;ESR1;NCOA2;ESRRB;ESRRA;NR1I2;AKT1;GPER1;CYP1B1;SHBG;CYP1A2;CYP2C8;CYP2C9;CYP3A4;TTR;ABCB1;ABCC1;ABCG2;SLCO1B1;SLCO2B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRA;AKT1;TOP2A;NCOA2;ESRRB;NCOA1;MET;NR1I2;ESR1;GPER1;ESR2 GO:0008283| cell proliferation AKT1;ESRRB;MET GO:0010507| negative regulation of autophagy AKT1;MET GO:0007165| signal transduction PTK2B;AKT1;MET;NR1I2;GPER1;ESR1;ESR2 GO:0016310| phosphorylation AKT1;PTK2B;MET GO:0006468| protein phosphorylation PTK2B;AKT1;MET GO:0000165| MAPKKK cascade PTK2B;MET GO:0018108| peptidyl-tyrosine phosphorylation PTK2B;MET GO:0007166| cell surface receptor linked signaling pathway MET;PTK2B 42813:[DB06314 DB00883] DB06314|SGX-523 MET DB00883|Isosorbide dinitrate NPR1;CYP3A4;CYP2E1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;NPR1 GO:0006468| protein phosphorylation MET;NPR1 42814:[DB06314 DB01033] DB06314|SGX-523 MET DB01033|Mercaptopurine HPRT1;PPAT;IMPDH1;IMPDH2;TPMT;XDH;AOX1;SLC22A8;ABCC4;ABCC5;SLC28A2;SLC28A3;SLC29A1;SLC29A2 common genes common pathways GO:0008283| cell proliferation SLC29A2;MET 42815:[DB06314 DB06372] DB06314|SGX-523 MET DB06372|Rilonacept IL1B;IL1A;IL1RN common genes common pathways GO:0000165| MAPKKK cascade MET;IL1B GO:0007165| signal transduction MET;IL1B GO:0008283| cell proliferation IL1A;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;MET;IL1A 42816:[DB06314 DB08814] DB06314|SGX-523 MET DB08814|Triflusal PTGS1;NFKB1;NOS2;PDE10A;ALB common genes common pathways GO:0007165| signal transduction PDE10A;MET;NFKB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NFKB1 42817:[DB06314 DB00365] DB06314|SGX-523 MET DB00365|Grepafloxacin gyrA;parC;CYP1A2;CYP3A4;ABCB1;ABCC1;SLC22A6;SLC22A2;SLC22A5;ABCC2 common genes common pathways 42818:[DB06314 DB11619] DB06314|SGX-523 MET DB11619|Gestrinone SHBG;PGR;NR3C1;AR;GNRHR;ESR1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;NR3C1;MET;ESR1 GO:0008283| cell proliferation AR;MET GO:0007165| signal transduction GNRHR;ESR1;MET;PGR;NR3C1;AR 42819:[DB06314 DB09272] DB06314|SGX-523 MET DB09272|Eluxadoline OPRM1;OPRD1;OPRK1;SLCO1B1;ABCC2;SLC22A8 common genes common pathways GO:0007165| signal transduction OPRD1;OPRK1;OPRM1;MET 42820:[DB06314 DB04871] DB06314|SGX-523 MET DB04871|Lorcaserin HTR2C;CYP1A2;CYP2A6;CYP2B6;CYP2C19;CYP2D6;CYP3A4;FMO1;CYP1A1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction HTR2C;MET 42821:[DB06314 DB00294] DB06314|SGX-523 MET DB00294|Etonogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;ESR1;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;MET;ESR1 42822:[DB06314 DB00657] DB06314|SGX-523 MET DB00657|Mecamylamine CHRNA2;CHRNA7;CHRNA4;CHRNB2 common genes common pathways GO:0007165| signal transduction MET;CHRNB2;CHRNA7;CHRNA4;CHRNA2 42823:[DB06314 DB08844] DB06314|SGX-523 MET DB08844|Uric Acid PYGL;SLC22A6;SLC22A8;SLC2A9 common genes common pathways 42824:[DB06314 DB01182] DB06314|SGX-523 MET DB01182|Propafenone SCN5A;KCNH2;ADRB1;ADRB2;CYP2D6;CYP3A4;CYP1A2;CYP2C8;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007165| signal transduction MET;ADRB2;ADRB1 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 42825:[DB06314 DB01104] DB06314|SGX-523 MET DB01104|Sertraline SLC6A4;SLC6A3;PGRMC1;SIGMAR1;CYP3A4;CYP2D6;CYP2C19;CYP2C9;CYP2B6;MAOB;MAOA;CYP2B;ALB;ABCB1 common genes common pathways 42826:[DB06314 DB00810] DB06314|SGX-523 MET DB00810|Biperiden CHRNA2;CHRM1;CYP2D6 common genes common pathways GO:0007165| signal transduction CHRNA2;MET;CHRM1 GO:0008283| cell proliferation CHRM1;MET 42827:[DB06314 DB01018] DB06314|SGX-523 MET DB01018|Guanfacine ADRA2A;ADRA2B;CYP3A4;CYP2C19 common genes common pathways GO:0007165| signal transduction ADRA2B;ADRA2A;MET 42828:[DB06314 DB01405] DB06314|SGX-523 MET DB01405|Temafloxacin gyrA;parC;CYP1A2 common genes common pathways 42829:[DB06314 DB13873] DB06314|SGX-523 MET DB13873|Fenofibric acid PPARA;PPARG;PPARD;NR1I2 common genes common pathways GO:0007165| signal transduction MET;NR1I2;PPARG GO:0008283| cell proliferation PPARD;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET;PPARG;PPARA 42830:[DB06314 DB05361] DB06314|SGX-523 MET DB05361|SR-123781A SERPINC1;F2R common genes common pathways GO:0007165| signal transduction MET;F2R 42831:[DB06314 DB01409] DB06314|SGX-523 MET DB01409|Tiotropium CHRM3;CHRM1;CHRM2;CHRM4;CHRM5;CYP2D6;CYP3A4;SLC22A5;SLC22A4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0008283| cell proliferation CHRM3;CHRM5;MET;CHRM4;CHRM1 GO:0007165| signal transduction CHRM1;CHRM4;CHRM2;MET;CHRM5;CHRM3 42832:[DB06314 DB00812] DB06314|SGX-523 MET DB00812|Phenylbutazone PTGS2;PTGIS;PTGS1;CYP2C9;CYP3A4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways 42833:[DB06314 DB00512] DB06314|SGX-523 MET DB00512|Vancomycin ALB;ORM1;ORM2 common genes common pathways 42834:[DB06314 DB00865] DB06314|SGX-523 MET DB00865|Benzphetamine SLC18A2;ADRA2A;ADRA1A;SLC6A3;CYP3A4;CYP2B6;POR common genes common pathways GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction MET;ADRA2A;ADRA1A 42835:[DB06314 DB13941] DB06314|SGX-523 MET DB13941|Piperaquine CYP3A4;CYP2C19;CYP2C9;CYP2B6;CYP2E1 common genes common pathways 42836:[DB06314 DB00160] DB06314|SGX-523 MET DB00160|L-Alanine AGXT;ABAT;KYNU;AARS2;PHYKPL;GPT2;GPT;NFS1;SLC36A1;SLC7A8;AGXT2;AARS;SLC1A4;SLC16A10 common genes common pathways 42837:[DB06314 DB00764] DB06314|SGX-523 MET DB00764|Mometasone NR3C1;PGR;CYP2C8;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PGR;MET GO:0007165| signal transduction MET;NR3C1;PGR 42838:[DB06314 DB00596] DB06314|SGX-523 MET DB00596|Ulobetasol NR3C1;SERPINA6 common genes common pathways GO:0007165| signal transduction NR3C1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 42839:[DB06314 DB00694] DB06314|SGX-523 MET DB00694|Daunorubicin TOP2A;TOP2B;CYP3A4;CYP3A5;CYP1A1;CYP1B1;XDH;POR;ABCB1;ABCC1;ABCC10;ABCC2;ABCC6;ABCB11;ABCG2 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 42840:[DB06314 DB00094] DB06314|SGX-523 MET DB00094|Urofollitropin FSHR common genes common pathways GO:0007165| signal transduction MET;FSHR 42841:[DB06314 DB00189] DB06314|SGX-523 MET DB00189|Ethchlorvynol GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRA5;GABRB1;GABRA6;GABRD;GABRB3;MET;GABRE;GABRQ;GABRP 42842:[DB06314 DB09395] DB06314|SGX-523 MET DB09395|Sodium acetate ACSS2 common genes common pathways 42843:[DB06314 DB01366] DB06314|SGX-523 MET DB01366|Procaterol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007165| signal transduction MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET 42844:[DB06314 DB00385] DB06314|SGX-523 MET DB00385|Valrubicin TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 42845:[DB06314 DB14596] DB06314|SGX-523 MET DB14596|Loteprednol etabonate NR3C1;CYP3A4;PON1 common genes common pathways GO:0007165| signal transduction NR3C1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 42846:[DB06314 DB01656] DB06314|SGX-523 MET DB01656|Roflumilast PDE4D;PDE4A;PDE4B;PDE4C;CYP3A4 common genes common pathways GO:0007165| signal transduction PDE4D;PDE4B;PDE4C;MET;PDE4A 42847:[DB06314 DB01440] DB06314|SGX-523 MET DB01440|gamma-Hydroxybutyric acid SLC52A2;GABRB1;SLC16A7;SLC16A1;SLC16A3 common genes common pathways GO:0007165| signal transduction MET;GABRB1 42848:[DB06314 DB08874] DB06314|SGX-523 MET DB08874|Fidaxomicin CYP3A4;ABCB1 common genes common pathways 42849:[DB06314 DB13036] DB06314|SGX-523 MET DB13036|Ramatroban PTGDR2 common genes common pathways GO:0007165| signal transduction PTGDR2;MET 42850:[DB06314 DB01144] DB06314|SGX-523 MET DB01144|Diclofenamide CA2;CA1;CA4;CA7;CA3 common genes common pathways 42851:[DB06314 DB12781] DB06314|SGX-523 MET DB12781|Balaglitazone CYP3A4;CYP2C8 common genes common pathways 42852:[DB06314 DB00558] DB06314|SGX-523 MET DB00558|Zanamivir NEU2 common genes common pathways 42853:[DB06314 DB01623] DB06314|SGX-523 MET DB01623|Thiothixene DRD2;DRD1;HTR2A;CYP1A2;CYP2D6;ALB;SLC22A1 common genes common pathways GO:0007165| signal transduction DRD2;HTR2A;DRD1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 42854:[DB06314 DB00033] DB06314|SGX-523 MET DB00033|Interferon gamma-1b IFNGR1;IFNGR2 common genes common pathways GO:0007165| signal transduction IFNGR1;MET GO:0007166| cell surface receptor linked signaling pathway IFNGR2;MET 42855:[DB06314 DB00857] DB06314|SGX-523 MET DB00857|Terbinafine SQLE;CYP2C9;CYP1A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;PTGS1;CYP11A1;CYP19A1 common genes common pathways 42856:[DB06314 DB04829] DB06314|SGX-523 MET DB04829|Lysergic acid diethylamide HTR1A;HTR2B;HTR6;CYP3A4;CYP2D6 common genes common pathways GO:0016310| phosphorylation HTR2B;MET GO:0007165| signal transduction HTR2B;HTR1A;HTR6;MET GO:0008283| cell proliferation MET;HTR1A GO:0010507| negative regulation of autophagy HTR2B;MET 42857:[DB06314 DB13997] DB06314|SGX-523 MET DB13997|Baloxavir marboxil UGT1A3;CYP3A4;ABCB5 common genes common pathways 42858:[DB06314 DB01083] DB06314|SGX-523 MET DB01083|Orlistat PNLIP;LIPF;FASN;CYP3A4;PLA2G4A common genes common pathways 42859:[DB06314 DB14582] DB06314|SGX-523 MET DB14582|Patisiran ALB;ORM1;ORM2 common genes common pathways 42860:[DB06314 DB00691] DB06314|SGX-523 MET DB00691|Moexipril ACE;ACE2;SLC15A1;SLC15A2 common genes common pathways 42861:[DB06314 DB05442] DB06314|SGX-523 MET DB05442|Etiprednol dicloacetate IL1B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;MET GO:0000165| MAPKKK cascade MET;IL1B GO:0007165| signal transduction MET;IL1B 42862:[DB06314 DB09060] DB06314|SGX-523 MET DB09060|Avibactam bla;bla;bla;bla;bla;ABCC2;SLC22A8 common genes common pathways 42863:[DB06314 DB00434] DB06314|SGX-523 MET DB00434|Cyproheptadine HRH1;HTR2A;HTR2C;CHRM1;CHRM2;CHRM3;HTR7;UGT1A3 common genes common pathways GO:0008283| cell proliferation CHRM1;CHRM3;MET GO:0007165| signal transduction CHRM1;HTR7;CHRM2;HRH1;MET;CHRM3;HTR2C;HTR2A 42864:[DB06314 DB00949] DB06314|SGX-523 MET DB00949|Felbamate GRIN2B;GRIN3A;GRIN2A;CYP3A4;CYP2C19;CYP2E1;CYP2C9 common genes common pathways GO:0000165| MAPKKK cascade GRIN2A;GRIN2B;MET 42865:[DB06314 DB08912] DB06314|SGX-523 MET DB08912|Dabrafenib BRAF;RAF1;SIK1;NEK11;LIMK1;CYP3A4;CYP2C8;CYP2B6;CYP2C9;ABCB1;ABCG2;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;MET GO:0000165| MAPKKK cascade RAF1;MET;BRAF GO:0008283| cell proliferation MET;RAF1 GO:0016310| phosphorylation SIK1;MET;BRAF;NEK11;RAF1;LIMK1 GO:0006468| protein phosphorylation BRAF;NEK11;MET;SIK1;LIMK1;RAF1 GO:0007165| signal transduction RAF1;LIMK1;MET;BRAF 42866:[DB06314 DB12465] DB06314|SGX-523 MET DB12465|Ketanserin HTR2A common genes common pathways GO:0007165| signal transduction MET;HTR2A 42867:[DB06314 DB09258] DB06314|SGX-523 MET DB09258|Bemiparin F10;SERPINC1;SERPIND1;SERPINA5 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;MET 42868:[DB06314 DB09046] DB06314|SGX-523 MET DB09046|Metreleptin LEPR common genes common pathways GO:0007166| cell surface receptor linked signaling pathway LEPR;MET GO:0010507| negative regulation of autophagy MET;LEPR 42869:[DB06314 DB05936] DB06314|SGX-523 MET DB05936|CVT-6883 ADORA2B common genes common pathways GO:0007165| signal transduction ADORA2B;MET 42870:[DB06314 DB00347] DB06314|SGX-523 MET DB00347|Trimethadione CACNA1G;CYP2E1;CYP3A4;CYP2C8;CYP2C9;CYP2C19 common genes common pathways 42871:[DB06314 DB11755] DB06314|SGX-523 MET DB11755|Tetrahydrocannabivarin CNR1;CNR2;GPR55;HTR1A;TRPV2;TRPM8;TRPA1 common genes common pathways GO:0007165| signal transduction CNR2;HTR1A;GPR55;MET;CNR1 GO:0008283| cell proliferation MET;HTR1A GO:0007166| cell surface receptor linked signaling pathway MET;TRPA1 42872:[DB06314 DB00378] DB06314|SGX-523 MET DB00378|Dydrogesterone PGR;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;MET 42873:[DB06314 DB01005] DB06314|SGX-523 MET DB01005|Hydroxyurea RRM1;CYP2D6 common genes common pathways 42874:[DB06314 DB08918] DB06314|SGX-523 MET DB08918|Levomilnacipran SLC6A4;SLC6A2;CYP3A4;CYP2C8;CYP2C19;CYP2D6;CYP2J2;ABCB1 common genes common pathways 42875:[DB06314 DB01998] DB06314|SGX-523 MET DB01998|2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol SERPINA1 common genes common pathways 42876:[DB06314 DB13168] DB06314|SGX-523 MET DB13168|Omega-6 fatty acids FADS2;FADS1;PTGS2;ALOX5 common genes common pathways 42877:[DB06314 DB03066] DB06314|SGX-523 MET DB03066|D-Lactic acid SLC16A7;SLC16A1;SLC16A3 common genes common pathways 42878:[DB06314 DB11892] DB06314|SGX-523 MET DB11892|Prulifloxacin CYP1A2 common genes common pathways 42879:[DB06314 DB06756] DB06314|SGX-523 MET DB06756|Glycine betaine BCL2;BCHE;PRODH common genes common pathways GO:0010507| negative regulation of autophagy MET;BCL2 GO:0008283| cell proliferation MET;BCL2 42880:[DB06314 DB00787] DB06314|SGX-523 MET DB00787|Acyclovir SLC22A1;SLC22A6;SLC22A8;SLC10A2;SLC47A1;SLC47A2 common genes common pathways 42881:[DB06314 DB09332] DB06314|SGX-523 MET DB09332|Kappadione F2;F7;F9;F10;PROC;GGCX;PROS1;VKORC1;POR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;F7;MET GO:0007166| cell surface receptor linked signaling pathway F2;MET 42882:[DB06314 DB01170] DB06314|SGX-523 MET DB01170|Guanethidine SLC6A2;CYP3A4 common genes common pathways 42883:[DB06314 DB00029] DB06314|SGX-523 MET DB00029|Anistreplase PLG;FGA;PLAUR;SERPINE1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;SERPINE1 GO:0007165| signal transduction MET;FGA;PLAUR 42884:[DB06314 DB03023] DB06314|SGX-523 MET DB03023|1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine LCK;LYN;SRC common genes common pathways GO:0008283| cell proliferation MET;SRC GO:0007165| signal transduction MET;LYN;SRC GO:0006468| protein phosphorylation MET;LYN;SRC;LCK GO:0016310| phosphorylation SRC;LCK;MET;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;LYN;LCK GO:0035635| entry of bacterium into host cell SRC;MET GO:0018108| peptidyl-tyrosine phosphorylation MET;LYN;SRC;LCK GO:0046854| phosphatidylinositol phosphorylation LCK;MET GO:0051897| positive regulation of protein kinase B signaling cascade LCK;SRC;MET 42885:[DB06314 DB11779] DB06314|SGX-523 MET DB11779|Danoprevir CYP3A4 common genes common pathways 42886:[DB06314 DB00550] DB06314|SGX-523 MET DB00550|Propylthiouracil TPO;MPO;DBH;CYP1A1 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 42887:[DB06314 DB06419] DB06314|SGX-523 MET DB06419|Cethromycin CYP3A5;CYP3A4 common genes common pathways 42888:[DB06314 DB11960] DB06314|SGX-523 MET DB11960|Carboxyamidotriazole CYP3A4 common genes common pathways 42889:[DB06314 DB09052] DB06314|SGX-523 MET DB09052|Blinatumomab CD19;CD3D common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD19;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;CD3D GO:0046854| phosphatidylinositol phosphorylation MET;CD19 GO:0007166| cell surface receptor linked signaling pathway MET;CD19;CD3D 42890:[DB06314 DB08834] DB06314|SGX-523 MET DB08834|Tauroursodeoxycholic acid SLCO1A2;SLC7A11 common genes common pathways 42891:[DB06314 DB01129] DB06314|SGX-523 MET DB01129|Rabeprazole ATP4A;CYP3A4;CYP2C19;CYP1A1;CYP1A2;CYP2C9;CYP2D6;CYP2C8;ABCG2 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 42892:[DB06314 DB06589] DB06314|SGX-523 MET DB06589|Pazopanib FLT1;KDR;FLT4;PDGFRA;PDGFRB;KIT;FGFR3;ITK;FGF1;SH2B3;CYP3A4;CYP2D6;CYP2C8;CYP1A2;ABCB1;ABCG2;SLCO1B1;UGT1A1 common genes common pathways GO:0008283| cell proliferation FGF1;MET GO:0007165| signal transduction KIT;ITK;PDGFRB;SH2B3;FGF1;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway PDGFRA;FLT1;FLT4;KDR;KIT;ITK;MET;PDGFRB GO:0016310| phosphorylation PDGFRA;FLT1;FLT4;KDR;ITK;KIT;FGFR3;MET;PDGFRB GO:0006468| protein phosphorylation ITK;KIT;FLT4;KDR;FLT1;PDGFRA;PDGFRB;MET;FGFR3 GO:0000165| MAPKKK cascade KIT;PDGFRA;PDGFRB;MET;FGF1;FGFR3 GO:0018108| peptidyl-tyrosine phosphorylation KDR;FLT4;KIT;PDGFRA;FLT1;PDGFRB;FGFR3;FGF1;MET GO:0046854| phosphatidylinositol phosphorylation PDGFRB;FGF1;MET;FGFR3;KIT;PDGFRA GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRB;FGF1;MET;FGFR3;KIT;PDGFRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;FGF1 42893:[DB06314 DB03153] DB06314|SGX-523 MET DB03153|3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol HPRT1 common genes common pathways 42894:[DB06314 DB12489] DB06314|SGX-523 MET DB12489|Mirvetuximab Soravtansine CYP3A4 common genes common pathways 42895:[DB06314 DB00698] DB06314|SGX-523 MET DB00698|Nitrofurantoin rpsJ;POR;ABCG2;ABCB11 common genes common pathways 42896:[DB06314 DB01261] DB06314|SGX-523 MET DB01261|Sitagliptin DPP4;CYP3A4;CYP2C8;ABCB1;SLC22A8 common genes common pathways 42897:[DB06314 DB00145] DB06314|SGX-523 MET DB00145|Glycine GCAT;ALAS1;ALAS2;GCSH;GARS;GRIN2A;BAAT;GPR18;GSS;GRIN2C;GLYAT;SLC36A1;SHMT2;GLYATL2;GLYATL1;AGXT2;SLC32A1;PIPOX;SLC6A5;GRIN3B;GLDC;SLC6A9;GLRA1;AGXT;GLRB;SHMT1;GLRA3;GLRA2;GNMT;GATM;SLC16A10 common genes common pathways GO:0000165| MAPKKK cascade GRIN2A;MET;GRIN2C GO:0007165| signal transduction GPR18;MET 42898:[DB06314 DB08892] DB06314|SGX-523 MET DB08892|Arbaclofen Placarbil GABBR1;GABBR2;SLC16A1 common genes common pathways GO:0007165| signal transduction GABBR1;GABBR2;MET 42899:[DB06314 DB00830] DB06314|SGX-523 MET DB00830|Phenmetrazine SLC6A2;SLC6A3 common genes common pathways 42900:[DB06314 DB11805] DB06314|SGX-523 MET DB11805|Saracatinib CYP3A4 common genes common pathways 42901:[DB06314 DB01708] DB06314|SGX-523 MET DB01708|Prasterone ESR1;ESR2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;AR;HSD17B1;SULT2A1;SULT2B1;PPARA;SIGMAR1;NR1I2;NR1I3;CYP3A4;CYP3A7 common genes common pathways GO:0000165| MAPKKK cascade GRIN2D;MET;GRIN2A;GRIN2B;GRIN1;GRIN2C GO:0008283| cell proliferation AR;MET GO:0007165| signal transduction NR1I3;GABRB1;GABRA6;GABRD;AR;GABRA5;GABRE;GABRQ;ESR1;ESR2;GABRP;GABRB3;MET;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;AR;GRIN1;ESR1;PPARA;ESR2;MET;NR1I2 42902:[DB06314 DB01108] DB06314|SGX-523 MET DB01108|Trilostane HSD3B1;HSD3B2;ESR1;ESR2;CYP3A4 common genes common pathways GO:0007165| signal transduction ESR1;ESR2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;MET 42903:[DB06314 DB04861] DB06314|SGX-523 MET DB04861|Nebivolol ADRB1;ADRB2;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction ADRB2;MET;ADRB1 42904:[DB06314 DB00052] DB06314|SGX-523 MET DB00052|Somatotropin GHR;PRLR common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;PRLR 42905:[DB06314 DB12243] DB06314|SGX-523 MET DB12243|Edaravone SLC22A6;SLC22A8 common genes common pathways 42906:[DB06314 DB09198] DB06314|SGX-523 MET DB09198|Lobeglitazone PPARG;CYP1A2;CYP2C9;CYP2C19;CYP3A4;CYP2C8;SLCO1B1;SLCO3A1;ABCB1 common genes common pathways GO:0007165| signal transduction MET;PPARG GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG 42907:[DB06314 DB05449] DB06314|SGX-523 MET DB05449|FM-VP4 ABCB1 common genes common pathways 42908:[DB06314 DB09348] DB06314|SGX-523 MET DB09348|Propiolactone ALB common genes common pathways 42909:[DB06314 DB06733] DB06314|SGX-523 MET DB06733|Bafilomycin A1 ATP6V1A common genes common pathways 42910:[DB06314 DB02056] DB06314|SGX-523 MET DB02056|Prostaglandin D2 AKR1C3;PTGDR2;SLCO2A1 common genes common pathways GO:0007165| signal transduction PTGDR2;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;AKR1C3 42911:[DB06314 DB01294] DB06314|SGX-523 MET DB01294|Bismuth Subsalicylate ALB;TF common genes common pathways 42912:[DB06314 DB04665] DB06314|SGX-523 MET DB04665|Coumarin CYP2A6;CYP2C9 common genes common pathways 42913:[DB06314 DB06643] DB06314|SGX-523 MET DB06643|Denosumab TNFSF11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNFSF11 42914:[DB06314 DB04821] DB06314|SGX-523 MET DB04821|Nomifensine SLC6A2;SLC6A3;MAOB;MAOA;MPO;SLC6A4;SLC18A2;ORM1 common genes common pathways 42915:[DB06314 DB00193] DB06314|SGX-523 MET DB00193|Tramadol OPRM1;SLC6A2;SLC6A4;HTR2C;OPRK1;OPRD1;GRIN3A;CHRNA7;CHRM3;CHRM1;CYP2D6;CYP3A4;CYP2B6;UGT1A1 common genes common pathways GO:0008283| cell proliferation CHRM1;MET;CHRM3 GO:0007165| signal transduction OPRD1;CHRNA7;OPRK1;OPRM1;CHRM1;CHRM3;HTR2C;MET 42916:[DB06314 DB01022] DB06314|SGX-523 MET DB01022|Phylloquinone GGCX;BGLAP common genes common pathways 42917:[DB06314 DB01075] DB06314|SGX-523 MET DB01075|Diphenhydramine HRH1;CHRM2;CYP2D6;CYP2C9;CYP2C19;CYP2C18;PTGS1;SLC22A2;SLC22A5 common genes common pathways GO:0007165| signal transduction HRH1;MET;CHRM2 42918:[DB06314 DB04576] DB06314|SGX-523 MET DB04576|Fleroxacin TOP2A;gyrA;parC;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 42919:[DB06314 DB02337] DB06314|SGX-523 MET DB02337|S-(D-Carboxybutyl)-L-Homocysteine BHMT common genes common pathways 42920:[DB06314 DB14641] DB06314|SGX-523 MET DB14641|Estriol tripropionate ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0007165| signal transduction ESR1;ESR2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;MET 42921:[DB06314 DB13998] DB06314|SGX-523 MET DB13998|Lonoctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;F10 GO:0007166| cell surface receptor linked signaling pathway MET;ASGR2;F2 GO:0008283| cell proliferation MET;LRP1 42922:[DB06314 DB04877] DB06314|SGX-523 MET DB04877|Voacamine ABCB1 common genes common pathways 42923:[DB06314 DB00611] DB06314|SGX-523 MET DB00611|Butorphanol OPRK1;OPRD1;OPRM1 common genes common pathways GO:0007165| signal transduction MET;OPRM1;OPRK1;OPRD1 42924:[DB06314 DB02105] DB06314|SGX-523 MET DB02105|3,5-Dinitrocatechol COMT common genes common pathways 42925:[DB06314 DB09072] DB06314|SGX-523 MET DB09072|Sodium oxybate ALDH5A1;ADHFE1 common genes common pathways 42926:[DB06314 DB03203] DB06314|SGX-523 MET DB03203|Sphingosine GLTP;PVR;ABCB1 common genes common pathways 42927:[DB06314 DB13988] DB06314|SGX-523 MET DB13988|SB-269970 HTR7 common genes common pathways GO:0007165| signal transduction MET;HTR7 42928:[DB06314 DB01049] DB06314|SGX-523 MET DB01049|Ergoloid mesylate DRD1;DRD5;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;CYP3A4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0008283| cell proliferation ADRA1B;HTR1A;ADRA1D;MET GO:0010507| negative regulation of autophagy MET;ADRA1A;HTR2B GO:0007165| signal transduction ADRB1;HTR2B;HTR1D;HTR1A;ADRA1B;HTR3A;DRD2;ADRA1A;ADRB3;ADRA2B;HTR2A;DRD4;HTR3C;HTR3B;DRD1;ADRA1D;DRD3;HTR7;HTR1B;HTR4;DRD5;HTR1E;HTR3E;HTR1F;ADRA2A;HTR2C;HTR6;MET;ADRB2;ADRA2C;HTR3D GO:0016310| phosphorylation HTR2B;MET GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;ADRB2;MET;DRD3 42929:[DB06314 DB00726] DB06314|SGX-523 MET DB00726|Trimipramine SLC6A4;SLC6A2;SLC6A3;HTR2A;HTR1A;ADRA1A;ADRA1B;DRD2;ADRA2B;HRH1;HTR2C;HTR3A;HTR1D;ADRA2A;DRD1;DRD5;ADRB1;ADRB2;ADRB3;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP3A4;CYP2D6;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET;ADRB2 GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation CHRM3;CHRM5;MET;CHRM4;CHRM1;ADRA1B;HTR1A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction CHRM3;HTR2C;ADRA2A;ADRB2;CHRM2;HRH1;CHRM5;MET;CHRM4;CHRM1;DRD5;ADRB3;HTR3A;DRD2;ADRA1A;ADRA2B;HTR2A;DRD1;ADRB1;HTR1A;HTR1D;ADRA1B GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET;CHRM4 42930:[DB06314 DB11726] DB06314|SGX-523 MET DB11726|Encenicline CHRNA7 common genes common pathways GO:0007165| signal transduction CHRNA7;MET 42931:[DB06314 DB00745] DB06314|SGX-523 MET DB00745|Modafinil SLC6A3;ADRA1B;CYP2C19;CYP3A4;CYP1A2;CYP2B6;CYP2C9;CYP3A5 common genes common pathways GO:0008283| cell proliferation MET;ADRA1B GO:0007165| signal transduction MET;ADRA1B 42932:[DB06314 DB06770] DB06314|SGX-523 MET DB06770|Benzyl alcohol CYP2C8;CYP1A1;ALDH2;CYP1A2;CYP2E1;CYP2D6 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 42933:[DB06314 DB01234] DB06314|SGX-523 MET DB01234|Dexamethasone NR3C1;NR0B1;ANXA1;NOS2;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP11A1;CYP17A1;CYP19A1;CYP1A1;CYP1B1;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2D6;CYP2E1;CYP3A43;CYP4A11;ABCB11;ABCB1;ABCC2;ABCG2;SLCO1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;NR1I2;MET GO:0007165| signal transduction ANXA1;NR1I2;MET;NR3C1 GO:0008283| cell proliferation MET;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway MET;ANXA1 42934:[DB06314 DB00779] DB06314|SGX-523 MET DB00779|Nalidixic acid TDO2;SLC22A6 common genes common pathways 42935:[DB06314 DB01016] DB06314|SGX-523 MET DB01016|Glyburide ABCC8;KCNJ11;KCNJ5;ABCC9;ABCB11;ABCA1;CFTR;KCNJ11;KCNJ8;CPT1A;CYP2C19;CYP3A4;CYP2C9;ALB;ABCC3;ABCB11;ABCB1;ABCC1;SLC15A1;SLCO1A2;SLC15A2;SLC22A6;ABCC2;ABCG2;SLC22A7;SLCO2B1 common genes common pathways GO:0007165| signal transduction MET;ABCC9;ABCC8 42936:[DB06314 DB05928] DB06314|SGX-523 MET DB05928|Dovitinib NR1I2;CYP1A1;CYP1A2;UGT1A3;UGT2B7;CYP2C19;CYP3A4;ABCC3;ABCG2;SLCO1B1;SLCO2B1;SLCO1B3;ABCB1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction MET;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET 42937:[DB06314 DB01562] DB06314|SGX-523 MET DB01562|1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine CYP2D6 common genes common pathways 42938:[DB06314 DB13952] DB06314|SGX-523 MET DB13952|Estradiol acetate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0010507| negative regulation of autophagy MET;BECN1 GO:0007165| signal transduction CHRNA4;ESR2;GPER1;ESR1;NR1I2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;NCOA2;MET;NR1I2;GPER1;ESR1;ESR2 42939:[DB06314 DB00016] DB06314|SGX-523 MET DB00016|Erythropoietin EPOR common genes common pathways GO:0007165| signal transduction EPOR;MET 42940:[DB06314 DB06704] DB06314|SGX-523 MET DB06704|Iobenguane SLC6A2 common genes common pathways 42941:[DB06314 DB00142] DB06314|SGX-523 MET DB00142|Glutamic Acid GRM1;GRM4;GRIK4;GRIK5;GRM7;GRM8;SLC1A7;OPLAH;PFAS;BCAT2;GRIN2D;GRID2;GRIN3B;GATB;GLS;GOT2;EPRS;ASNS;GLUL;GOT1;TAT;GPT;GGCX;SLC1A3;SLC1A2;SLC1A1;GCLC;SLC1A6;GLUD2;GMPS;BCAT1;ABAT;GRIN1;FPGS;ENPEP;GRIN2A;GRIN2B;GRIN2C;GIG18;EARS2;LGSN;NADSYN1;CCBL2;NAGS;AADAT;GRIN3A;GPT2;SLC25A18;SLC25A22;AASS;GLS2;DNPEP;GRID1;SLC7A11;CPQ;PSAT1;GLUD1;GRIK1;GRIA1;GCLM;FOLH1;GAD2;GAD1;FTCD;GRIA2;GRIA3;GRIA4;ALDH18A1;GRIK2;GRIK3;SLC16A10;SLC16A1 common genes common pathways GO:0008283| cell proliferation FPGS;GLUL;BCAT1;ENPEP;MET GO:0016310| phosphorylation MET;ALDH18A1 GO:0007165| signal transduction GRIA2;MET;GRM7;GRIA1;GRM1;GRM4;GRM8 GO:0000165| MAPKKK cascade GRIN2C;GRIN1;GRIN2A;GRIN2B;MET;GRIN2D GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;MET 42942:[DB06314 DB00872] DB06314|SGX-523 MET DB00872|Conivaptan AVPR1A;AVPR2;CYP3A4 common genes common pathways GO:0007165| signal transduction AVPR1A;AVPR2;MET 42943:[DB06314 DB00439] DB06314|SGX-523 MET DB00439|Cerivastatin HMGCR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2B6;UGT1A1;ABCB1;ABCC2;ABCG2;SLCO1B1;ABCB11 common genes common pathways 42944:[DB06314 DB00593] DB06314|SGX-523 MET DB00593|Ethosuximide CACNA1G;CYP2E1;CYP3A4;CYP3A43 common genes common pathways 42945:[DB06314 DB00508] DB06314|SGX-523 MET DB00508|Triflupromazine DRD1;DRD2;HTR2B;CHRM1;CHRM2;BCHE;ABCB1 common genes common pathways GO:0016310| phosphorylation MET;HTR2B GO:0007165| signal transduction CHRM2;MET;CHRM1;DRD2;DRD1;HTR2B GO:0010507| negative regulation of autophagy HTR2B;MET GO:0008283| cell proliferation MET;CHRM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 42946:[DB06314 DB06594] DB06314|SGX-523 MET DB06594|Agomelatine HTR2C;MTNR1A;MTNR1B;CYP1A2;CYP2C9 common genes common pathways GO:0007165| signal transduction MTNR1B;HTR2C;MTNR1A;MET 42947:[DB06314 DB13173] DB06314|SGX-523 MET DB13173|Cerliponase alfa IGF2R common genes common pathways GO:0007165| signal transduction MET;IGF2R 42948:[DB06314 DB06680] DB06314|SGX-523 MET DB06680|Asoprisnil PGR common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PGR GO:0007165| signal transduction MET;PGR 42949:[DB06314 DB00486] DB06314|SGX-523 MET DB00486|Nabilone CNR2;CNR1;CYP2E1;CYP2C8;CYP2C9 common genes common pathways GO:0007165| signal transduction CNR2;CNR1;MET 42950:[DB06314 DB05120] DB06314|SGX-523 MET DB05120|AT1391 INSR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;INSR GO:0018108| peptidyl-tyrosine phosphorylation MET;INSR GO:0006468| protein phosphorylation INSR;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway INSR;MET GO:0016310| phosphorylation MET;INSR 42951:[DB06314 DB09207] DB06314|SGX-523 MET DB09207|AS-8112 DRD2;DRD3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD3;DRD2 GO:0007165| signal transduction DRD2;MET;DRD3 42952:[DB06314 DB00198] DB06314|SGX-523 MET DB00198|Oseltamivir CES1;NEU1;NEU2;ABCC4;SLC15A1;SLC22A8 common genes common pathways 42953:[DB06314 DB00188] DB06314|SGX-523 MET DB00188|Bortezomib PSMB5;PSMB1;CYP3A4;CYP2C19;CYP2D6;CYP1A2;CYP2C9 common genes common pathways GO:0000165| MAPKKK cascade PSMB1;MET;PSMB5 42954:[DB06314 DB08871] DB06314|SGX-523 MET DB08871|Eribulin BCL2;TUBB1 common genes common pathways GO:0010507| negative regulation of autophagy MET;BCL2 GO:0008283| cell proliferation BCL2;MET 42955:[DB06314 DB05996] DB06314|SGX-523 MET DB05996|Glembatumumab vedotin GPNMB common genes common pathways GO:0007165| signal transduction GPNMB;MET GO:0050918| positive chemotaxis MET;GPNMB 42956:[DB06314 DB05915] DB06314|SGX-523 MET DB05915|MYO-029 MSTN common genes common pathways 42957:[DB06314 DB00304] DB06314|SGX-523 MET DB00304|Desogestrel PGR;ESR1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET;PGR GO:0007165| signal transduction PGR;ESR1;MET 42958:[DB06314 DB09223] DB06314|SGX-523 MET DB09223|Blonanserin DRD2;DRD3;HTR2A;CYP3A4;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET;DRD3 GO:0007165| signal transduction HTR2A;DRD2;MET;DRD3 42959:[DB06314 DB09285] DB06314|SGX-523 MET DB09285|Morniflumate ALOX5;PTGS2;LTB4R;TBXA2R;ALOX5;PTGS2 common genes common pathways GO:0007165| signal transduction TBXA2R;LTB4R;MET 42960:[DB06314 DB03048] DB06314|SGX-523 MET DB03048|6-Carboxymethyluracil DPYD common genes common pathways 42961:[DB06314 DB01106] DB06314|SGX-523 MET DB01106|Levocabastine HRH1;NTSR2 common genes common pathways GO:0007165| signal transduction MET;HRH1;NTSR2 GO:0007166| cell surface receptor linked signaling pathway MET;NTSR2 42962:[DB06314 DB01210] DB06314|SGX-523 MET DB01210|Levobunolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction MET;ADRB2;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 42963:[DB06314 DB06217] DB06314|SGX-523 MET DB06217|Vernakalant SCN5A;KCNA5;KCND3;KCNH2;CYP2D6 common genes common pathways 42964:[DB06314 DB07960] DB06314|SGX-523 MET DB07960|5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID NEU2 common genes common pathways 42965:[DB06314 DB02266] DB06314|SGX-523 MET DB02266|Flufenamic Acid PTGS2;PTGS1;AKR1C3;AR;PPARA;PPARG;TTR;SLC22A6 common genes common pathways GO:0007165| signal transduction MET;PPARG;AR GO:0008283| cell proliferation MET;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;MET;PPARG;PPARA GO:0051897| positive regulation of protein kinase B signaling cascade AKR1C3;MET 42966:[DB06314 DB02377] DB06314|SGX-523 MET DB02377|Guanine PNP;gpt;GCH1 common genes common pathways 42967:[DB06314 DB12305] DB06314|SGX-523 MET DB12305|Dasotraline SLC6A3;SLC6A4;SLC6A2 common genes common pathways 42968:[DB06314 DB01209] DB06314|SGX-523 MET DB01209|Dezocine OPRM1;OPRK1 common genes common pathways GO:0007165| signal transduction MET;OPRK1;OPRM1 42969:[DB06314 DB01174] DB06314|SGX-523 MET DB01174|Phenobarbital GABRA1;CHRNA4;CHRNA7;GRIA2;GRIK2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;NR1I2;CYP2C19;CYP2C9;CYP2B6;CYP2C8;CYP3A4;CYP1A2;CYP2A6;CYP2E1;CYP3A5;CYP4A11;CYP1A1;CYP1B1;CYP2C18;CYP3A7;CYP4B1;UGT1A1;UGT2B7;ABCB1;ABCC3;ABCB11;ABCC1;SLCO2A1;ABCC2 common genes common pathways GO:0000165| MAPKKK cascade GRIN2C;GRIN1;GRIN2B;GRIN2A;GRIN2D;MET GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction NR1I2;GRIA2;MET;CHRNA7;CHRNA4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;NR1I2;MET 42970:[DB06314 DB08992] DB06314|SGX-523 MET DB08992|Eperisone CYP3A4 common genes common pathways 42971:[DB06314 DB12752] DB06314|SGX-523 MET DB12752|Bucindolol CYP2D6 common genes common pathways 42972:[DB06314 DB11251] DB06314|SGX-523 MET DB11251|Tocopherol CYP4F2;CYP3A4;VLDLR;LDLR;TTPA;SEC14L4;SEC14L2;SEC14L3;APOBR;SCARB1;ABCB1 common genes common pathways GO:0007165| signal transduction VLDLR;MET 42973:[DB06314 DB00973] DB06314|SGX-523 MET DB00973|Ezetimibe SOAT1;NPC1L1;ANPEP;UGT1A1;UGT1A3;UGT2B15;UGT2B7;CYP3A4;CYP2C8;ABCB1;ABCC2;SLCO1B1;ABCG5;ABCC3;ABCG2;ABCG8;ABCB11 common genes common pathways GO:0007165| signal transduction ANPEP;MET 42974:[DB06314 DB01577] DB06314|SGX-523 MET DB01577|Metamfetamine SLC6A3;SLC6A4;SLC6A2;SLC18A2;SLC18A1;TAAR1;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;CYP2D6;SLC22A3;SLC22A5 common genes common pathways GO:0007165| signal transduction ADRA2A;MET;ADRA2C;TAAR1;ADRA2B 42975:[DB06314 DB09330] DB06314|SGX-523 MET DB09330|Osimertinib EGFR;CYP3A4;CYP1A2;ABCB1;ABCG2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade EGFR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;EGFR GO:0046854| phosphatidylinositol phosphorylation EGFR;MET GO:0000165| MAPKKK cascade EGFR;MET GO:0007166| cell surface receptor linked signaling pathway EGFR;MET GO:0018108| peptidyl-tyrosine phosphorylation EGFR;MET GO:0008283| cell proliferation MET;EGFR GO:0007165| signal transduction EGFR;MET GO:0016310| phosphorylation EGFR;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway EGFR;MET GO:0006468| protein phosphorylation MET;EGFR 42976:[DB06314 DB00051] DB06314|SGX-523 MET DB00051|Adalimumab TNF common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF GO:0000165| MAPKKK cascade MET;TNF 42977:[DB06314 DB05740] DB06314|SGX-523 MET DB05740|RPI-78M CHRNA2;CHRNB2;CHRNA7;CHRNA4;CHRNA10;CHRNA9 common genes common pathways GO:0007165| signal transduction CHRNA2;CHRNA4;CHRNA7;MET;CHRNB2;CHRNA9;CHRNA10 42978:[DB06314 DB00451] DB06314|SGX-523 MET DB00451|Levothyroxine THRA;THRB;CYP2C8;UGT1A1;TTR;SERPINA7;ALB;SLCO1C1;SLC16A2;ABCB1;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4A1;SLCO4C1;SLC7A5;SLCO2B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter THRA;MET;THRB 42979:[DB06314 DB03756] DB06314|SGX-523 MET DB03756|Doconexent PPARA;PPARG;RXRA;RXRB;RXRG;SREBF1;CYP2C9;FABP7 common genes common pathways GO:0007165| signal transduction PPARG;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRB;MET;PPARG;RXRA;PPARA;RXRG;SREBF1 42980:[DB06314 DB06362] DB06314|SGX-523 MET DB06362|Becatecarin TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 42981:[DB06314 DB03052] DB06314|SGX-523 MET DB03052|Dazoxiben TBXAS1 common genes common pathways 42982:[DB06314 DB01024] DB06314|SGX-523 MET DB01024|Mycophenolic acid IMPDH1;IMPDH2;UGT1A1;UGT1A9;UGT2B7;UGT1A7;UGT1A6 common genes common pathways 42983:[DB06314 DB00473] DB06314|SGX-523 MET DB00473|Hexylcaine SCN5A;SCN10A common genes common pathways 42984:[DB06314 DB00441] DB06314|SGX-523 MET DB00441|Gemcitabine RRM1;TYMS;CMPK1;CDA;DCK;ABCB1;ABCC10;SLC29A1;SLC28A1;SLC29A2;SLC28A3 common genes common pathways GO:0008283| cell proliferation MET;SLC29A2 GO:0016310| phosphorylation MET;DCK;CMPK1 GO:0007166| cell surface receptor linked signaling pathway CDA;MET 42985:[DB06314 DB01046] DB06314|SGX-523 MET DB01046|Lubiprostone CLCN2;CBR1 common genes common pathways 42986:[DB06314 DB03147] DB06314|SGX-523 MET DB03147|Flavin adenine dinucleotide thiO;POR;GCDH;ACADM;DAO;putA;MAOA;ACADS;IL4I1;NOS1;NQO1;ERO1B;GSR;CYB5R3;trxB;gor;metF;soxA;TPR;NQO2;IVD;XDH;DPYD;TXNRD1;fpr;ACAD8;AIFM1;nadB;DLD;CYB5R1;MAOB;FDXR;ACOX1;murB;GFER;murB;metF;lpdA;lpd;fpr;NDUFA9;MAOB common genes common pathways GO:0007165| signal transduction TXNRD1;MET GO:0008283| cell proliferation TXNRD1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NOS1;MET 42987:[DB06314 DB00235] DB06314|SGX-523 MET DB00235|Milrinone PDE3A common genes common pathways GO:0007165| signal transduction MET;PDE3A 42988:[DB06314 DB00540] DB06314|SGX-523 MET DB00540|Nortriptyline SLC6A2;SLC6A4;HTR2A;HTR1A;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2C;HTR6;ADRA1B;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;PGRMC1;SIGMAR1;CYP2D6;CYP3A4;CYP1A2;CYP2C19;CYP3A5;PTGS1;CYP2E1;ALB;ORM1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2;CHRM4 GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation CHRM1;CHRM4;ADRA1D;CHRM5;MET;CHRM3;ADRA1B;HTR1A GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction ADRA1D;CHRM4;CHRM1;CHRM3;HTR6;HTR2C;ADRA2A;HRH1;CHRM5;MET;ADRB2;CHRM2;ADRA2C;ADRB1;HTR1A;ADRA1B;ADRA1A;DRD2;ADRB3;ADRA2B;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;ADRB2;MET 42989:[DB06314 DB05015] DB06314|SGX-523 MET DB05015|Belinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2C8;CYP2C9;CYP1A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;HDAC4;HDAC5;HDAC3;HDAC1;HDAC2 42990:[DB06314 DB01396] DB06314|SGX-523 MET DB01396|Digitoxin ATP1A1;CYP3A4;CYP11A1;ALB;SLCO1A2;SLCO4C1;ABCB1 common genes common pathways 42991:[DB06314 DB01390] DB06314|SGX-523 MET DB01390|Sodium bicarbonate SLC4A4;SLC4A7;SLC4A8;SLC4A5;SLC4A10 common genes common pathways 42992:[DB06314 DB06717] DB06314|SGX-523 MET DB06717|Fosaprepitant CYP3A4;CYP2C9 common genes common pathways 42993:[DB06314 DB03619] DB06314|SGX-523 MET DB03619|Deoxycholic Acid ctaD;ctaC;NR1H4;GSTP1;GPBAR1;ABCB11;SLCO1A2;SLC10A2;SLC10A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1H4 GO:0007165| signal transduction NR1H4;GPBAR1;MET 42994:[DB06314 DB00404] DB06314|SGX-523 MET DB00404|Alprazolam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C9;CYP3A7;CYP3A4;CYP3A5 common genes common pathways GO:0007165| signal transduction MET;GABRB3;GABRQ;GABRE;GABRP;GABRA5;GABRA6;GABRB1;GABRD 42995:[DB06314 DB01407] DB06314|SGX-523 MET DB01407|Clenbuterol ADRB2;ADRB1;ADRB3;NGF;TNF;CYP1A1 common genes common pathways GO:0007165| signal transduction ADRB3;ADRB1;ADRB2;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;NGF GO:0008283| cell proliferation MET;CYP1A1 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0000165| MAPKKK cascade MET;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;ADRB2;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF 42996:[DB06314 DB01439] DB06314|SGX-523 MET DB01439|3-Methylthiofentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007165| signal transduction OPRD1;OPRK1;OPRM1;MET 42997:[DB06314 DB00072] DB06314|SGX-523 MET DB00072|Trastuzumab ERBB2;EGFR;C1R;C1QA;C1QB;C1QC;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;FCGR3A;CYP19A1 common genes common pathways GO:0000165| MAPKKK cascade MET;ERBB2;EGFR GO:0018108| peptidyl-tyrosine phosphorylation MET;EGFR;ERBB2 GO:0007166| cell surface receptor linked signaling pathway MET;ERBB2;EGFR GO:0008283| cell proliferation MET;ERBB2;EGFR GO:0006468| protein phosphorylation EGFR;ERBB2;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;ERBB2;EGFR GO:0016310| phosphorylation EGFR;ERBB2;MET GO:0007165| signal transduction EGFR;FCGR2B;FCGR2C;ERBB2;FCGR1A;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;EGFR;ERBB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;EGFR GO:0046854| phosphatidylinositol phosphorylation MET;ERBB2;EGFR 42998:[DB06314 DB00959] DB06314|SGX-523 MET DB00959|Methylprednisolone NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 GO:0007165| signal transduction MET;NR3C1 42999:[DB06314 DB01411] DB06314|SGX-523 MET DB01411|Pranlukast CYSLTR1;TNF;IL5;RNASE3;NFKB1;MUC2;CYP3A4;CYP2C9;ABCC2 common genes common pathways GO:0000165| MAPKKK cascade MET;IL5;TNF GO:0007166| cell surface receptor linked signaling pathway MET;CYSLTR1 GO:0018108| peptidyl-tyrosine phosphorylation IL5;MET GO:0007165| signal transduction NFKB1;MET;CYSLTR1 GO:0051897| positive regulation of protein kinase B signaling cascade TNF;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NFKB1;TNF 43000:[DB06314 DB00041] DB06314|SGX-523 MET DB00041|Aldesleukin IL2RB;IL2RA;IL2RG;PTGS2;PLA2G4A;CYP3A4;XDH;CYP2E1 common genes common pathways GO:0007165| signal transduction IL2RB;IL2RG;MET GO:0008283| cell proliferation IL2RA;MET GO:0007166| cell surface receptor linked signaling pathway MET;IL2RA GO:0000165| MAPKKK cascade IL2RG;MET;IL2RB;IL2RA 43001:[DB06314 DB13146] DB06314|SGX-523 MET DB13146|Fluciclovine (18F) SLC1A5;SLC7A7;SLC7A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;GRIA1;GRIA2;GRIA3;GRIA4;ABCB1;ABCC4 common genes common pathways GO:0000165| MAPKKK cascade GRIN2D;MET;GRIN2A;GRIN2B;GRIN1;GRIN2C GO:0007165| signal transduction GRIA1;MET;GRIA2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;MET 43002:[DB06314 DB09555] DB06314|SGX-523 MET DB09555|Dexchlorpheniramine maleate HRH1;CYP2D6;CYP3A4;SLC22A1;SLC22A2 common genes common pathways GO:0007165| signal transduction HRH1;MET 43003:[DB06314 DB01429] DB06314|SGX-523 MET DB01429|Aprindine SCN5A;CALM1;CYP2D6;ORM1 common genes common pathways GO:0000165| MAPKKK cascade MET;CALM1 43004:[DB06314 DB09338] DB06314|SGX-523 MET DB09338|Mersalyl ALPL;AQP1;SLC16A1;ITIH1;PCK1 common genes common pathways 43005:[DB06314 DB00379] DB06314|SGX-523 MET DB00379|Mexiletine SCN5A;AHR;CYP1A2;CYP2D6;CYP2B6;CYP2E1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;MET 43006:[DB06314 DB09418] DB06314|SGX-523 MET DB09418|Potassium perchlorate SLC5A5;ALB common genes common pathways 43007:[DB06314 DB00526] DB06314|SGX-523 MET DB00526|Oxaliplatin CYP1A1;CYP1B1;CYP2E1;GSTT1;MT1A;MT2A;MPO;SOD1;GSTP1;GSTM1;NQO1;SLC22A2;SLC31A1;SLC22A3;ABCG2;ABCC2;ATP7B;ATP7A common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 43008:[DB06314 DB05254] DB06314|SGX-523 MET DB05254|Fibrinolysin SERPINE1;PLAU common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;SERPINE1 GO:0007165| signal transduction PLAU;MET 43009:[DB06314 DB01127] DB06314|SGX-523 MET DB01127|Econazole NR1I2;CYP19A1;CYP2E1;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET 43010:[DB06314 DB12952] DB06314|SGX-523 MET DB12952|Methylprednisone CYP3A4 common genes common pathways 43011:[DB06314 DB02552] DB06314|SGX-523 MET DB02552|Geranyl Diphosphate ispDF;FDPS;GGPS1 common genes common pathways 43012:[DB06314 DB08699] DB06314|SGX-523 MET DB08699|1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine CAMK2G common genes common pathways GO:0016310| phosphorylation MET;CAMK2G GO:0006468| protein phosphorylation MET;CAMK2G GO:0000165| MAPKKK cascade CAMK2G;MET 43013:[DB06314 DB00380] DB06314|SGX-523 MET DB00380|Dexrazoxane TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 43014:[DB06314 DB03800] DB06314|SGX-523 MET DB03800|2'-deoxyuridylic acid dut;thyA;thyA;TYMS;pol;dut common genes common pathways 43015:[DB06314 DB06243] DB06314|SGX-523 MET DB06243|Eflornithine ODC1 common genes common pathways 43016:[DB06314 DB00195] DB06314|SGX-523 MET DB00195|Betaxolol ADRB1;ADRB2;CYP1A2;CYP2D6 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction ADRB2;MET;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 43017:[DB06314 DB04789] DB06314|SGX-523 MET DB04789|5-methyltetrahydrofolic acid AMT;ABCC2 common genes common pathways 43018:[DB06314 DB09288] DB06314|SGX-523 MET DB09288|Propacetamol PTGS1;PTGS2;TRPV1;CNR1;BCHE;CYP3A4;CYP2E1;CYP1A2;CYP2D6;UGT1A1;UGT1A6;UGT1A9;UGT2B15;UGT1A10;SULT1A1;SULT1A3;SULT1E1;SULT2A1;NAT2;CYP2C9 common genes common pathways GO:0007165| signal transduction MET;CNR1 GO:0007166| cell surface receptor linked signaling pathway TRPV1;MET 43019:[DB06314 DB01363] DB06314|SGX-523 MET DB01363|Ephedra SLC6A3;SLC6A2;ADRA2A;ADRA2B;ADRA2C;MAOA;MAOB;ADRB1;ADRB2;ADRB3;SLC6A4;SLC18A2;SLC18A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007165| signal transduction ADRA2B;ADRB3;ADRB1;ADRA2C;ADRB2;MET;ADRA2A GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET 43020:[DB06314 DB00499] DB06314|SGX-523 MET DB00499|Flutamide AR;AHR;NR1I2;CYP3A4;CYP1A2;CYP1A1;CYP1B1;CYP2C19;CYP3A5 common genes common pathways GO:0008283| cell proliferation MET;AR;CYP1A1 GO:0007165| signal transduction NR1I2;MET;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET;AHR;AR 43021:[DB06314 DB14540] DB06314|SGX-523 MET DB14540|Hydrocortisone butyrate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0007165| signal transduction NR3C1;ANXA1;MET GO:0007166| cell surface receptor linked signaling pathway ANXA1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 43022:[DB06314 DB01369] DB06314|SGX-523 MET DB01369|Quinupristin rplJ;rplV;CYP3A4 common genes common pathways 43023:[DB06314 DB00474] DB06314|SGX-523 MET DB00474|Methohexital GABRA1;CYP2C19 common genes common pathways 43024:[DB06314 DB13953] DB06314|SGX-523 MET DB13953|Estradiol benzoate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0010507| negative regulation of autophagy MET;BECN1 GO:0007165| signal transduction GPER1;ESR1;ESR2;MET;NR1I2;CHRNA4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRG;NCOA2;NR1I2;MET;ESR2;GPER1;ESR1 43025:[DB06314 DB09291] DB06314|SGX-523 MET DB09291|Rolapitant CYP2D6;CYP3A4;ABCG2;ABCB1 common genes common pathways 43026:[DB06314 DB01351] DB06314|SGX-523 MET DB01351|Amobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP2A6 common genes common pathways GO:0007165| signal transduction MET;GRIA2;GABRA5;GABRA6;CHRNA7;CHRNA4 43027:[DB06314 DB01380] DB06314|SGX-523 MET DB01380|Cortisone acetate NR3C1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 GO:0007165| signal transduction MET;NR3C1 43028:[DB06314 DB00435] DB06314|SGX-523 MET DB00435|Nitric Oxide GUCY1A2;MT1A;IDO1;ALDH2;CYP1A2;CYP2B6;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;GUCY1A2 43029:[DB06314 DB13872] DB06314|SGX-523 MET DB13872|Lormetazepam GABRA2;GABRG2;GABRA3;GABRA5;GABRA1 common genes common pathways GO:0007165| signal transduction GABRA5;MET 43030:[DB06314 DB14503] DB06314|SGX-523 MET DB14503|Sodium phosphate, monobasic, unspecified form SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0007165| signal transduction SLC20A1;MET 43031:[DB06314 DB06190] DB06314|SGX-523 MET DB06190|Solabegron ADRB3 common genes common pathways GO:0007165| signal transduction MET;ADRB3 43032:[DB06314 DB06787] DB06314|SGX-523 MET DB06787|Hexocyclium CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM4;MET;CHRM2;CHRM3 GO:0008283| cell proliferation CHRM3;MET;CHRM4;CHRM1 GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET 43033:[DB06314 DB06652] DB06314|SGX-523 MET DB06652|Vicriviroc CCR5;CYP3A4;CYP3A5;CYP2C9 common genes common pathways GO:0007165| signal transduction MET;CCR5 GO:0000165| MAPKKK cascade MET;CCR5 GO:0007166| cell surface receptor linked signaling pathway MET;CCR5 43034:[DB06314 DB06412] DB06314|SGX-523 MET DB06412|Oxymetholone AR;NPPB;MAOA;CYP2D6;SRD5A1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ALB;SHBG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;AR GO:0007165| signal transduction MET;AR GO:0008283| cell proliferation MET;AR GO:0007166| cell surface receptor linked signaling pathway MET;NPPB 43035:[DB06314 DB01228] DB06314|SGX-523 MET DB01228|Encainide SCN5A;CYP2D6 common genes common pathways 43036:[DB06314 DB00604] DB06314|SGX-523 MET DB00604|Cisapride HTR4;HTR3A;HTR2A;KCNH2;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C19;CYP2C8;CYP2C9;CYP2D6 common genes common pathways GO:0007165| signal transduction HTR4;MET;HTR3A;HTR2A 43037:[DB06314 DB08901] DB06314|SGX-523 MET DB08901|Ponatinib ABL1;BCR;KIT;RET;TEK;FLT3;FGFR1;FGFR2;FGFR3;FGFR4;LCK;SRC;LYN;KDR;PDGFRA;CYP3A4;CYP2C8;CYP2D6;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0007165| signal transduction KIT;BCR;SRC;RET;MET;TEK;LYN GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway LCK;KDR;KIT;PDGFRA;RET;LYN;TEK;FLT3;MET GO:0016310| phosphorylation KDR;LCK;BCR;KIT;FGFR1;PDGFRA;RET;SRC;FGFR4;FGFR2;TEK;ABL1;FGFR3;LYN;MET;FLT3 GO:0006468| protein phosphorylation FGFR1;KIT;BCR;KDR;LCK;RET;SRC;PDGFRA;FGFR2;FGFR4;FLT3;MET;LYN;FGFR3;ABL1;TEK GO:0008283| cell proliferation MET;SRC GO:0035635| entry of bacterium into host cell MET;SRC GO:0018108| peptidyl-tyrosine phosphorylation RET;SRC;PDGFRA;KIT;BCR;FGFR1;KDR;LCK;MET;FLT3;TEK;ABL1;FGFR3;LYN;FGFR2;FGFR4 GO:0000165| MAPKKK cascade FGFR2;FGFR4;MET;FGFR3;TEK;FGFR1;KIT;RET;PDGFRA GO:0046854| phosphatidylinositol phosphorylation FGFR4;FGFR2;FGFR3;MET;LCK;KIT;FGFR1;PDGFRA GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;FGFR2 GO:0051897| positive regulation of protein kinase B signaling cascade FGFR3;TEK;MET;FGFR4;FGFR2;PDGFRA;SRC;LCK;FGFR1;KIT 43038:[DB06314 DB11581] DB06314|SGX-523 MET DB11581|Venetoclax BCL2;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0008283| cell proliferation MET;BCL2 GO:0010507| negative regulation of autophagy MET;BCL2 43039:[DB06314 DB01138] DB06314|SGX-523 MET DB01138|Sulfinpyrazone ABCC2;ABCC1;SLC22A12;NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C8;FABP2;ABCC3;ABCC4;ABCC5;ABCC6;ABCC1;ABCC2;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET GO:0007165| signal transduction NR1I2;MET 43040:[DB06314 DB06713] DB06314|SGX-523 MET DB06713|Norelgestromin PGR;ALB;AR;STS;CYP3A4 common genes common pathways GO:0008283| cell proliferation MET;AR GO:0007165| signal transduction PGR;AR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;AR;MET 43041:[DB06314 DB00637] DB06314|SGX-523 MET DB00637|Astemizole HRH1;KCNH2;KCNH1;MAPT;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0007165| signal transduction HRH1;MET GO:0031116| positive regulation of microtubule polymerization MAPT;MET 43042:[DB06314 DB01252] DB06314|SGX-523 MET DB01252|Mitiglinide ABCC8;PPARG;UGT1A3;UGT2B7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;MET GO:0007165| signal transduction ABCC8;PPARG;MET 43043:[DB06314 DB00814] DB06314|SGX-523 MET DB00814|Meloxicam PTGS2;PTGS1;CYP2C9;CYP3A4;PGD;CYP2C8;ABCC4 common genes common pathways 43044:[DB06314 DB06262] DB06314|SGX-523 MET DB06262|Droxidopa ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;DDC;SLC6A2;SLC16A10 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1B;MET;ADRA1D GO:0007165| signal transduction ADRA2B;ADRB3;ADRA1A;ADRA1B;ADRB1;ADRA2C;ADRB2;MET;ADRA2A;ADRA1D GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43045:[DB06314 DB01254] DB06314|SGX-523 MET DB01254|Dasatinib ABL1;SRC;EPHA2;LCK;YES1;KIT;PDGFRB;STAT5B;ABL2;FYN;BTK;NR4A3;BCR;CSK;EPHA5;EPHB4;FGR;FRK;HSPA8;LYN;MAPK14;PPAT;CYP3A4;CYP1A1;CYP1A2;CYP1B1;CYP3A5;FMO3;ABCB1;ABCG2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRB;MET;FYN;KIT;LCK;SRC GO:0045944| positive regulation of transcription from RNA polymerase II promoter YES1;MET;NR4A3;STAT5B;MAPK14 GO:0046854| phosphatidylinositol phosphorylation LCK;KIT;FYN;MET;PDGFRB GO:0000165| MAPKKK cascade KIT;PDGFRB;MET;FYN GO:0018108| peptidyl-tyrosine phosphorylation EPHA5;PDGFRB;BTK;FGR;ABL1;LYN;EPHB4;EPHA2;FYN;STAT5B;MET;ABL2;LCK;KIT;BCR;SRC GO:0007166| cell surface receptor linked signaling pathway MET;FYN;MAPK14 GO:0035635| entry of bacterium into host cell MET;SRC GO:0008283| cell proliferation MET;SRC;CYP1A1 GO:0006468| protein phosphorylation LCK;YES1;BCR;KIT;SRC;MAPK14;PDGFRB;EPHA5;FGR;BTK;FYN;LYN;EPHA2;EPHB4;ABL1;FRK;CSK;MET;ABL2 GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway ABL2;MET;EPHA2;EPHB4;LYN;FYN;CSK;FRK;FGR;BTK;PDGFRB;EPHA5;KIT;YES1;LCK GO:0016310| phosphorylation SRC;BCR;KIT;YES1;LCK;ABL2;MET;ABL1;FRK;CSK;FYN;LYN;EPHA2;EPHB4;BTK;FGR;EPHA5;MAPK14;PDGFRB GO:0007165| signal transduction BCR;KIT;SRC;MAPK14;PDGFRB;STAT5B;ABL2;MET;LYN 43046:[DB06314 DB01059] DB06314|SGX-523 MET DB01059|Norfloxacin parC;gyrA;TOP2A;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP1A1;SLC22A5;SLC22A6 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 43047:[DB06314 DB05303] DB06314|SGX-523 MET DB05303|OMS-103HP TNF;IL1R1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNF GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF GO:0007165| signal transduction MET;IL1R1 GO:0007166| cell surface receptor linked signaling pathway IL1R1;MET GO:0000165| MAPKKK cascade TNF;MET 43048:[DB06314 DB00002] DB06314|SGX-523 MET DB00002|Cetuximab EGFR;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction EGFR;FCGR2B;FCGR2C;FCGR1A;MET GO:0006468| protein phosphorylation MET;EGFR GO:0016310| phosphorylation MET;EGFR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;EGFR GO:0008283| cell proliferation EGFR;MET GO:0007166| cell surface receptor linked signaling pathway MET;EGFR GO:0018108| peptidyl-tyrosine phosphorylation EGFR;MET GO:0000165| MAPKKK cascade MET;EGFR GO:0046854| phosphatidylinositol phosphorylation EGFR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade MET;EGFR 43049:[DB06314 DB02701] DB06314|SGX-523 MET DB02701|Nicotinamide LDHA;PARP1;SIRT5;BST1;CYP2D6;CYP2E1;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;BST1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PARP1 43050:[DB06314 DB00338] DB06314|SGX-523 MET DB00338|Omeprazole ATP4A;AHR;CYP1A1;CYP1A2;CYP1B1;CYP2C8;CYP2C9;CYP2C18;CYP2D6;CYP3A4;CYP11A1;CYP2C19;ABCG2;ABCC3;ABCB1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;AHR 43051:[DB06314 DB09146] DB06314|SGX-523 MET DB09146|Iron saccharate HBA1;TF common genes common pathways 43052:[DB06314 DB09449] DB06314|SGX-523 MET DB09449|Sodium phosphate, monobasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0007165| signal transduction SLC20A1;MET 43053:[DB06314 DB00533] DB06314|SGX-523 MET DB00533|Rofecoxib PTGS2;ELN;CYP1A2;CYP3A4;PTGS1;CYP2C8;CYP2C9;ABCC4 common genes common pathways GO:0008283| cell proliferation ELN;MET 43054:[DB06314 DB00083] DB06314|SGX-523 MET DB00083|Botulinum Toxin Type A SNAP25;RHOB common genes common pathways 43055:[DB06314 DB13269] DB06314|SGX-523 MET DB13269|Dichlorobenzyl alcohol SCN1A;SCN10A;SCN11A;SCN2A;SCN3A;SCN4A;SCN5A;SCN7A;SCN8A;SCN9A;SCN1B;SCN2B;SCN3B;SCN4B common genes common pathways 43056:[DB06314 DB06772] DB06314|SGX-523 MET DB06772|Cabazitaxel TUBA4A;TUBB1;CYP3A4;CYP3A5;CYP2C8;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 43057:[DB06314 DB13775] DB06314|SGX-523 MET DB13775|Tertatolol CYP2D6 common genes common pathways 43058:[DB06314 DB09200] DB06314|SGX-523 MET DB09200|Rivoglitazone CYP3A4;CYP2C8 common genes common pathways 43059:[DB06314 DB13950] DB06314|SGX-523 MET DB13950|WIN 55212-2 CYP3A4 common genes common pathways 43060:[DB06314 DB01395] DB06314|SGX-523 MET DB01395|Drospirenone PGR;NR3C2;AR;PTGS2;BCHE;CYP3A4 common genes common pathways GO:0008283| cell proliferation AR;MET GO:0007165| signal transduction PGR;NR3C2;AR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;PGR;MET 43061:[DB06314 DB01126] DB06314|SGX-523 MET DB01126|Dutasteride SRD5A2;SRD5A1;CYP3A4 common genes common pathways 43062:[DB06314 DB06370] DB06314|SGX-523 MET DB06370|Indisulam CYP2C9;CYP3A4;CYP2E1;CYP2D6 common genes common pathways 43063:[DB06314 DB13866] DB06314|SGX-523 MET DB13866|Etynodiol CYP3A4 common genes common pathways 43064:[DB06314 DB11348] DB06314|SGX-523 MET DB11348|Calcium Phosphate CASR;CALR;CIB1;PDCD6;SRI;CHP1;SPARC;CANX;FBN2;S100B;CASQ2;RGN;PEF1;S100A6;TPT1;CIB2;S100A13;CASQ1;NUCB1;NUCB2;CALM1;FBN3;GCA;CADPS;CALM2;CALM3;S100A16;CALB2;CAPS;CADPS2;CALR3;NRXN1;NCS1;CALB1;S100G;ALB;SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3;TRPV6;SLC8A1;TRPV5;RYR1;RYR2;PKD2L1;RYR3;PKD1L3;CATSPER1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1A;CACNA1G;CACNA1H;CACNA1I;CACNA1E common genes common pathways GO:0048754| branching morphogenesis of a tube MET;CASR GO:0007165| signal transduction SLC20A1;SPARC;SRI;CASR;S100A6;MET;CACNA1I GO:0008283| cell proliferation S100B;MET GO:0000165| MAPKKK cascade MET;CALM1 43065:[DB06314 DB09389] DB06314|SGX-523 MET DB09389|Norgestrel PGR;SRD5A1;AR;CYP3A4;CYP19A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PGR;AR GO:0008283| cell proliferation MET;AR GO:0007165| signal transduction PGR;AR;MET 43066:[DB06314 DB12191] DB06314|SGX-523 MET DB12191|Obatoclax BCL2 common genes common pathways GO:0008283| cell proliferation BCL2;MET GO:0010507| negative regulation of autophagy MET;BCL2 43067:[DB06314 DB08807] DB06314|SGX-523 MET DB08807|Bopindolol ADRB1;ADRB2;HTR1A;HTR1B;ADRB3;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0008283| cell proliferation MET;HTR1A GO:0007165| signal transduction HTR1B;MET;ADRB2;HTR1A;ADRB1;ADRB3 43068:[DB06314 DB11130] DB06314|SGX-523 MET DB11130|Opium OPRD1;OPRK1;OPRM1;CYP2D6;CYP3A4;ALB;B2M common genes common pathways GO:0007165| signal transduction OPRD1;MET;OPRK1;OPRM1 43069:[DB06314 DB06734] DB06314|SGX-523 MET DB06734|Bafilomycin B1 ATP6V1A common genes common pathways 43070:[DB06314 DB00589] DB06314|SGX-523 MET DB00589|Lisuride DRD2;DRD3;DRD4;DRD1;DRD5;HTR1A;HTR1D;HTR2B;HTR2A;HTR2C;HTR1B;ADRA2A;ADRA2B;ADRA2C;HTR7;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET GO:0008283| cell proliferation HTR1A;MET GO:0010507| negative regulation of autophagy MET;HTR2B GO:0016310| phosphorylation MET;HTR2B GO:0007165| signal transduction DRD5;HTR1B;HTR7;DRD3;MET;ADRA2C;ADRA2A;HTR2C;HTR1D;HTR1A;HTR2B;DRD1;DRD4;ADRA2B;HTR2A;DRD2 43071:[DB06314 DB09502] DB06314|SGX-523 MET DB09502|Fludeoxyglucose F-18 HK1;SLC2A4;SLC2A2;SLC2A1;SLC2A3;SLC2A9;SLC2A5;SLC2A6;SLC2A7;SLC2A8;SLC2A10;SLC2A11;SLC2A12 common genes common pathways GO:0016310| phosphorylation HK1;MET 43072:[DB06314 DB05505] DB06314|SGX-523 MET DB05505|NM-702 TBXAS1 common genes common pathways 43073:[DB06314 DB01200] DB06314|SGX-523 MET DB01200|Bromocriptine DRD2;DRD3;HTR1D;ADRA2A;HTR1A;ADRA2C;ADRA2B;HTR2B;DRD4;HTR2A;HTR1B;HTR2C;DRD5;DRD1;ADRA1A;ADRA1B;ADRA1D;HTR7;CYP3A4;ABCB1 common genes common pathways GO:0016310| phosphorylation MET;HTR2B GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction MET;ADRA2C;ADRA2A;HTR2C;DRD5;HTR7;HTR1B;ADRA1D;DRD3;DRD1;HTR2A;ADRA2B;DRD4;DRD2;ADRA1A;ADRA1B;HTR1D;HTR1A;HTR2B GO:0010507| negative regulation of autophagy MET;HTR2B;ADRA1A GO:0008283| cell proliferation ADRA1B;HTR1A;MET;ADRA1D GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET 43074:[DB06314 DB01240] DB06314|SGX-523 MET DB01240|Epoprostenol P2RY12;PTGIR;PTGIS common genes common pathways GO:0007165| signal transduction MET;P2RY12;PTGIR 43075:[DB06314 DB11607] DB06314|SGX-523 MET DB11607|Efmoroctocog alfa VWF common genes common pathways 43076:[DB06314 DB05039] DB06314|SGX-523 MET DB05039|Indacaterol ADRB2;CYP3A4;UGT1A1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007165| signal transduction MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET 43077:[DB06314 DB04825] DB06314|SGX-523 MET DB04825|Prenylamine CALM1;MYLK2;CYP3A4 common genes common pathways GO:0016310| phosphorylation MET;MYLK2 GO:0006468| protein phosphorylation MYLK2;MET GO:0000165| MAPKKK cascade CALM1;MET 43078:[DB06314 DB04964] DB06314|SGX-523 MET DB04964|Oregovomab MUC16 common genes common pathways 43079:[DB06314 DB05476] DB06314|SGX-523 MET DB05476|WX-UK1 PLAUR common genes common pathways GO:0007165| signal transduction MET;PLAUR 43080:[DB06314 DB09029] DB06314|SGX-523 MET DB09029|Secukinumab IL17A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL17A;MET 43081:[DB06314 DB00836] DB06314|SGX-523 MET DB00836|Loperamide OPRM1;OPRD1;OPRK1;CACNA1A;POMC;CALM1;NR1I3;CYP3A4;CYP2C8;CYP2B6;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I3;POMC;MET GO:0007165| signal transduction OPRD1;NR1I3;MET;POMC;OPRM1;OPRK1 GO:0000165| MAPKKK cascade CALM1;MET 43082:[DB06314 DB00210] DB06314|SGX-523 MET DB00210|Adapalene RARG;RARB;RXRG;RXRB;RARA;RXRA;PTGS2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRG;RARG;RARA;RXRB;MET;RXRA;RARB GO:0006468| protein phosphorylation MET;RARA GO:0007165| signal transduction MET;RARB;RARA 43083:[DB06314 DB12332] DB06314|SGX-523 MET DB12332|Rucaparib PARP1;PARP2;PARP3;CYP2D6;CYP1A2;CYP3A4;CYP3A5;CYP3A7;CYP3A43;CYP2C19;CYP2C9;CYP2C8;UGT1A1;ABCB1;ABCG2;SLC47A1;SLC47A2;SLC22A1;ABCC4;SLCO1B1;SLCO1B3;SLC22A6;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PARP1;MET 43084:[DB06314 DB01155] DB06314|SGX-523 MET DB01155|Gemifloxacin parC;gyrA;CYP1A2 common genes common pathways 43085:[DB06314 DB05431] DB06314|SGX-523 MET DB05431|MLN-977 ALOX5 common genes common pathways 43086:[DB06314 DB02998] DB06314|SGX-523 MET DB02998|Methyltrienolone PGR;AR;NCOA2;NR3C2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PGR;NCOA2;AR GO:0008283| cell proliferation MET;AR GO:0007165| signal transduction AR;NR3C2;PGR;MET 43087:[DB06314 DB14635] DB06314|SGX-523 MET DB14635|Curcumin sulfate PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0007165| signal transduction MET;PPARG;VDR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PPARG;MET;VDR 43088:[DB06314 DB00877] DB06314|SGX-523 MET DB00877|Sirolimus MTOR;FKBP1A;FGF2;CYP3A4;CYP3A5;CYP3A7;ABCB1;SLCO1B1;SLC47A1 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation MET;FGF2 GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;FGF2;MET GO:0050918| positive chemotaxis FGF2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter FGF2;MET GO:0010507| negative regulation of autophagy MTOR;MET GO:0007165| signal transduction MET;FGF2;MTOR GO:0016310| phosphorylation MET;MTOR GO:0006468| protein phosphorylation MTOR;MET GO:0000165| MAPKKK cascade MET;FGF2 GO:0018108| peptidyl-tyrosine phosphorylation MET;FGF2 43089:[DB06314 DB11712] DB06314|SGX-523 MET DB11712|Tezacaftor CFTR;CYP3A4;CYP3A5;ALB common genes common pathways 43090:[DB06314 DB02813] DB06314|SGX-523 MET DB02813|2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone HEXB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter HEXB;MET 43091:[DB06314 DB12334] DB06314|SGX-523 MET DB12334|Milataxel TUBB1;TUBB common genes common pathways 43092:[DB06314 DB07462] DB06314|SGX-523 MET DB07462|(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE COMT common genes common pathways 43093:[DB06314 DB09303] DB06314|SGX-523 MET DB09303|Evolocumab PCSK9 common genes common pathways 43094:[DB06314 DB06212] DB06314|SGX-523 MET DB06212|Tolvaptan AVPR2;AVPR1A;CYP3A4;ABCB1 common genes common pathways GO:0007165| signal transduction AVPR1A;AVPR2;MET 43095:[DB06314 DB00438] DB06314|SGX-523 MET DB00438|Ceftazidime mrcA;SLC22A5;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 43096:[DB06314 DB05668] DB06314|SGX-523 MET DB05668|Palifosfamide DNMT1 common genes common pathways 43097:[DB06314 DB03403] DB06314|SGX-523 MET DB03403|Cytidine-5'-Monophosphate ispDF;CMPK1;cmk;UCK2;coaBC common genes common pathways GO:0016310| phosphorylation MET;UCK2;CMPK1 43098:[DB06314 DB00685] DB06314|SGX-523 MET DB00685|Trovafloxacin gyrA;parC;TOP2A;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43099:[DB06314 DB06237] DB06314|SGX-523 MET DB06237|Avanafil PDE5A;CYP3A4 common genes common pathways GO:0007165| signal transduction PDE5A;MET 43100:[DB06314 DB04074] DB06314|SGX-523 MET DB04074|alpha-Ketoisovalerate panB;leuA;BCAT2;SLC16A7;SLC16A1;SLC16A3 common genes common pathways 43101:[DB06314 DB01102] DB06314|SGX-523 MET DB01102|Arbutamine ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0007165| signal transduction ADRB3;ADRB1;ADRB2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43102:[DB06314 DB04843] DB06314|SGX-523 MET DB04843|Mepenzolate CHRM1;CHRM3 common genes common pathways GO:0008283| cell proliferation CHRM1;MET;CHRM3 GO:0007165| signal transduction CHRM3;MET;CHRM1 43103:[DB06314 DB11703] DB06314|SGX-523 MET DB11703|Acalabrutinib BTK;CYP3A4;CYP3A5;CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;BTK GO:0016310| phosphorylation MET;BTK GO:0006468| protein phosphorylation BTK;MET GO:0018108| peptidyl-tyrosine phosphorylation BTK;MET 43104:[DB06314 DB00655] DB06314|SGX-523 MET DB00655|Estrone ESR1;ESR2;AR;CYP19A1;SHBG;CYP1A1;CYP1A2;CYP3A4;CYP1B1;CYP2B6;CYP2C9;CYP2E1;CYP3A5;CYP4A11;ALB;SLCO2B1;ABCB1;SLCO1A2;ABCG2;SLCO1B1;SLC22A8 common genes common pathways GO:0007165| signal transduction AR;MET;ESR2;ESR1 GO:0008283| cell proliferation CYP1A1;AR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR2;ESR1;MET;AR 43105:[DB06314 DB00696] DB06314|SGX-523 MET DB00696|Ergotamine HTR1D;HTR1B;HTR2A;DRD2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;SLC6A2;DRD1;DRD5;HTR1A;HTR1F;HTR2C;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0007165| signal transduction ADRA1B;HTR1D;HTR1A;HTR2B;DRD1;ADRA2B;HTR2A;DRD2;ADRA1A;DRD5;HTR1B;ADRA1D;MET;ADRA2A;HTR2C;HTR1F GO:0016310| phosphorylation HTR2B;MET GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0010507| negative regulation of autophagy MET;HTR2B;ADRA1A GO:0008283| cell proliferation ADRA1D;MET;HTR1A;ADRA1B 43106:[DB06314 DB05087] DB06314|SGX-523 MET DB05087|Ganaxolone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6 common genes common pathways GO:0007165| signal transduction MET;GABRA6;GABRA5 43107:[DB06314 DB04840] DB06314|SGX-523 MET DB04840|Debrisoquin SLC6A2;CYP2D6;CYP1A1;ABCB1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 43108:[DB06314 DB00886] DB06314|SGX-523 MET DB00886|Omapatrilat ACE;MME common genes common pathways 43109:[DB06314 DB05351] DB06314|SGX-523 MET DB05351|Dexlansoprazole ATP4A;ATP4B;CYP2C19;CYP3A4 common genes common pathways 43110:[DB06314 DB14642] DB06314|SGX-523 MET DB14642|Lypressin AVPR1A;AVPR2;AVPR1B;ABCC2 common genes common pathways GO:0007165| signal transduction AVPR1A;AVPR2;MET;AVPR1B 43111:[DB06314 DB00635] DB06314|SGX-523 MET DB00635|Prednisone NR3C1;HSD11B1;CYP3A4;CYP2C19;ALB;ABCB1;SLCO1A2 common genes common pathways GO:0007165| signal transduction NR3C1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 43112:[DB06314 DB06536] DB06314|SGX-523 MET DB06536|Tesaglitazar PPARA;PPARG common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG;PPARA GO:0007165| signal transduction PPARG;MET 43113:[DB06314 DB01219] DB06314|SGX-523 MET DB01219|Dantrolene RYR1;CYP3A4 common genes common pathways 43114:[DB06314 DB00845] DB06314|SGX-523 MET DB00845|Clofazimine ABCB11;CYP3A4;ABCB11;ABCB1 common genes common pathways 43115:[DB06314 DB09065] DB06314|SGX-523 MET DB09065|Cobicistat CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP3A43;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 43116:[DB06314 DB09166] DB06314|SGX-523 MET DB09166|Etizolam GABRA1;GABRA2;GABRA3;GABRG2;PTAFR;CYP3A4;CYP2C18;CYP2C19 common genes common pathways GO:0007165| signal transduction PTAFR;MET 43117:[DB06314 DB12945] DB06314|SGX-523 MET DB12945|Dihydralazine CYP1A2 common genes common pathways 43118:[DB06314 DB04889] DB06314|SGX-523 MET DB04889|Bicifadine SLC6A2;SLC6A4;DRD2;CYP2D6;MAOB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0007165| signal transduction DRD2;MET 43119:[DB06314 DB00782] DB06314|SGX-523 MET DB00782|Propantheline CHRM1 common genes common pathways GO:0007165| signal transduction MET;CHRM1 GO:0008283| cell proliferation CHRM1;MET 43120:[DB06314 DB00422] DB06314|SGX-523 MET DB00422|Methylphenidate SLC6A3;SLC6A2;SLC6A4 common genes common pathways 43121:[DB06314 DB14508] DB06314|SGX-523 MET DB14508|Lithium succinate IMPA2;IMPA1;GSK3B;GRIA3 common genes common pathways GO:0006468| protein phosphorylation MET;GSK3B GO:0016310| phosphorylation MET;GSK3B GO:0007165| signal transduction IMPA1;MET;IMPA2 GO:0046854| phosphatidylinositol phosphorylation MET;IMPA1;IMPA2 43122:[DB06314 DB04872] DB06314|SGX-523 MET DB04872|Osanetant TACR3 common genes common pathways GO:0007165| signal transduction MET;TACR3 43123:[DB06314 DB00502] DB06314|SGX-523 MET DB00502|Haloperidol DRD2;DRD1;GRIN2B;HTR2A;DRD3;MCHR1;SLC18A2;CYP3A5;CYP3A7;CYP1A2;CYP2D6;CYP3A4;CBR1;UGT1A9;CYP1A1;CYP2C19;CYP2C9;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD3;DRD2 GO:0000165| MAPKKK cascade MET;GRIN2B GO:0007165| signal transduction MET;MCHR1;DRD3;DRD1;HTR2A;DRD2 GO:0008283| cell proliferation MET;CYP1A1 43124:[DB06314 DB05434] DB06314|SGX-523 MET DB05434|ABT-510 FGF2;HGF;VEGFA;CXCL8 common genes common pathways GO:0048754| branching morphogenesis of a tube MET;VEGFA GO:0007165| signal transduction CXCL8;MET;FGF2 GO:0008283| cell proliferation MET;HGF GO:0010507| negative regulation of autophagy HGF;MET GO:0018108| peptidyl-tyrosine phosphorylation HGF;FGF2;MET GO:1901299| MET;HGF GO:0000165| MAPKKK cascade MET;FGF2;HGF GO:0046854| phosphatidylinositol phosphorylation HGF;MET;FGF2 GO:0048012| hepatocyte growth factor receptor signaling pathway HGF;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;FGF2;VEGFA;HGF GO:0051897| positive regulation of protein kinase B signaling cascade HGF;FGF2;MET GO:0050918| positive chemotaxis HGF;VEGFA;MET;FGF2 43125:[DB06314 DB01008] DB06314|SGX-523 MET DB01008|Busulfan CYP3A4;GSTA2;GSTA1;GSTM1;GSTP1;MGST2 common genes common pathways 43126:[DB06314 DB00503] DB06314|SGX-523 MET DB00503|Ritonavir pol;NR1I2;CYP2D6;CYP2C9;CYP2C19;CYP2B6;CYP2C8;CYP1A2;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43;UGT1A1;ALB;ABCB1;ABCC1;SLCO1A2;ABCC2;ABCG2;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET GO:0007165| signal transduction NR1I2;MET 43127:[DB06314 DB06211] DB06314|SGX-523 MET DB06211|Doripenem mrcA;DPEP1;SLC22A8 common genes common pathways 43128:[DB06314 DB00517] DB06314|SGX-523 MET DB00517|Anisotropine methylbromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM2;MET;CHRM3;CHRM1 GO:0008283| cell proliferation CHRM3;MET;CHRM1 43129:[DB06314 DB08838] DB06314|SGX-523 MET DB08838|Agmatine ADRA2C;NISCH;CHRNA1;GRIN1;KCNJ1;CACNA1B;ASIC3;CYP3A4;SLC22A1;SLC22A2;SLC22A3;SLC7A7 common genes common pathways GO:0000165| MAPKKK cascade GRIN1;MET GO:0007165| signal transduction ADRA2C;MET;ASIC3;CHRNA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;GRIN1 43130:[DB06314 DB00131] DB06314|SGX-523 MET DB00131|Adenosine phosphate CREB1;PIM1;PDE4B;PYGL;PRKAB1;HINT1;PDE4D;ACSS1;ACSS2;PRKAA1;PRKAB2;ADCY1;ACSL1;FBP1;ADK;AMPD1;APRT common genes common pathways GO:0008283| cell proliferation PIM1;MET GO:0006468| protein phosphorylation PRKAA1;PRKAB2;PRKAB1;MET;CREB1;PIM1 GO:0016310| phosphorylation MET;PRKAA1;PIM1;ADK GO:0007165| signal transduction PRKAB2;ADCY1;PRKAA1;MET;PRKAB1;PDE4D;CREB1;PDE4B;HINT1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter CREB1;MET 43131:[DB06314 DB00594] DB06314|SGX-523 MET DB00594|Amiloride SCNN1A;SCNN1B;SCNN1G;SCNN1D;AOC1;ASIC2;ASIC1;SLC9A1;PLAU;AOC1;AOC1;SLC22A2;SLC22A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;SLC9A1 GO:0007165| signal transduction PLAU;ASIC1;MET 43132:[DB06314 DB06288] DB06314|SGX-523 MET DB06288|Amisulpride DRD2;DRD3;HTR7;HTR2A common genes common pathways GO:0007165| signal transduction MET;HTR7;DRD3;DRD2;HTR2A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET 43133:[DB06314 DB00569] DB06314|SGX-523 MET DB00569|Fondaparinux SERPINC1;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;F10 43134:[DB06314 DB11358] DB06314|SGX-523 MET DB11358|Evening primrose oil ELOVL5;FADS1;FADS2 common genes common pathways 43135:[DB06314 DB09282] DB06314|SGX-523 MET DB09282|Molsidomine GUCY1A2;GUCY1A2;PDE5A common genes common pathways GO:0007165| signal transduction PDE5A;MET;GUCY1A2 43136:[DB06314 DB00630] DB06314|SGX-523 MET DB00630|Alendronic acid FDPS;PTPN4;PTPRS;PTPRE;ATP6V1A common genes common pathways 43137:[DB06314 DB00237] DB06314|SGX-523 MET DB00237|Butabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GABRP;GABRE;GABRQ;MET;GABRB3;GRIA2;GABRD;GABRA6;GABRB1;CHRNA7;CHRNA4;GABRA5 43138:[DB06314 DB11094] DB06314|SGX-523 MET DB11094|Vitamin D VDR;GC;CYP2R1;CYP27B1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;VDR GO:0007165| signal transduction VDR;MET 43139:[DB06314 DB01080] DB06314|SGX-523 MET DB01080|Vigabatrin GABBR1;ABAT;CYP2C9;SLC36A1 common genes common pathways GO:0007165| signal transduction MET;GABBR1 43140:[DB06314 DB05218] DB06314|SGX-523 MET DB05218|PN0621 TNF common genes common pathways GO:0000165| MAPKKK cascade TNF;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF 43141:[DB06314 DB09053] DB06314|SGX-523 MET DB09053|Ibrutinib BTK;CYP3A4;CYP3A5;CYP2D6;ALB;ORM1;ORM2 common genes common pathways GO:0006468| protein phosphorylation MET;BTK GO:0016310| phosphorylation BTK;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway BTK;MET GO:0018108| peptidyl-tyrosine phosphorylation BTK;MET 43142:[DB06314 DB00276] DB06314|SGX-523 MET DB00276|Amsacrine TOP2A;KCNH2;ORM1;ALB;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43143:[DB06314 DB00458] DB06314|SGX-523 MET DB00458|Imipramine SLC6A2;HTR2A;SLC6A4;HRH1;ADRA1A;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;KCND2;KCND3;HTR2C;ADRA1B;HTR7;DRD1;DRD5;DRD2;KCNH2;SLC6A3;HTR1A;HTR6;KCNH1;ORM2;CYP2C19;CYP2D6;CYP1A2;CYP3A4;CYP3A7;CYP2B6;CYP2C18;CYP2E1;ORM1;ALB;ABCB1;SLC22A2;SLC22A3;SLC22A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0008283| cell proliferation ADRA1D;CHRM4;CHRM1;CHRM3;MET;CHRM5;HTR1A;ADRA1B GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1D;HTR7;CHRM4;CHRM1;DRD5;CHRM3;HTR6;HTR2C;HRH1;MET;CHRM5;CHRM2;HTR1A;ADRA1B;ADRA1A;DRD2;HTR2A;DRD1 GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET 43144:[DB06314 DB14018] DB06314|SGX-523 MET DB14018|Bromotheophylline CYP1A2 common genes common pathways 43145:[DB06314 DB00346] DB06314|SGX-523 MET DB00346|Alfuzosin ADRA1A;ADRA1B;ADRA1D;KCNH2;CYP3A4 common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction ADRA1B;ADRA1A;ADRA1D;MET GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1D;MET;ADRA1B 43146:[DB06314 DB09265] DB06314|SGX-523 MET DB09265|Lixisenatide GLP1R common genes common pathways GO:0007166| cell surface receptor linked signaling pathway GLP1R;MET GO:0007165| signal transduction GLP1R;MET 43147:[DB06314 DB11586] DB06314|SGX-523 MET DB11586|Asunaprevir CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP3A4;CYP3A5;CYP2A6;CYP2B6;CYP2C9;CYP2C19;CYP2D6;ABCB1;SLCO1B1;SLCO2B1;SLCO1B1;SLCO1B3;SLCO2B1 common genes common pathways 43148:[DB06314 DB00675] DB06314|SGX-523 MET DB00675|Tamoxifen ESR1;ESR2;EBP;PRKCA;PRKCB;PRKCD;PRKCE;PRKCG;PRKCI;PRKCQ;PRKCZ;AR;KCNH2;NR1I2;ESRRG;SHBG;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP1A1;CYP1B1;FMO1;FMO3;CYP2C8;CES1;CYP19A1;CYP2A6;CYP2E1;UGT1A10;SULT1A1;ABCB1;ABCG2;ABCC2;ABCB11 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1;AR GO:0016310| phosphorylation MET;PRKCE;PRKCB;PRKCZ;PRKCQ;PRKCA;PRKCG;PRKCD;PRKCI GO:0006468| protein phosphorylation PRKCG;PRKCI;PRKCD;PRKCZ;PRKCB;MET;PRKCE;PRKCQ;PRKCA GO:0007165| signal transduction PRKCD;EBP;AR;ESR2;ESR1;NR1I2;PRKCB;PRKCZ;PRKCE;MET GO:0007166| cell surface receptor linked signaling pathway PRKCZ;MET GO:0018108| peptidyl-tyrosine phosphorylation PRKCD;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;MET;NR1I2;ESRRG;AR 43149:[DB06314 DB14065] DB06314|SGX-523 MET DB14065|Lomerizine ABCB1;CYP3A4 common genes common pathways 43150:[DB06314 DB01019] DB06314|SGX-523 MET DB01019|Bethanechol CHRM2;CHRM1;CHRM3;CHRM4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0007165| signal transduction CHRM1;CHRM4;MET;CHRM2;CHRM3 GO:0008283| cell proliferation MET;CHRM3;CHRM1;CHRM4 43151:[DB06314 DB13800] DB06314|SGX-523 MET DB13800|Calcium levulinate CALM1;CASQ1;CALB2 common genes common pathways GO:0000165| MAPKKK cascade MET;CALM1 43152:[DB06314 DB08613] DB06314|SGX-523 MET DB08613|2,2,2-TRIFLUORO-1-{5-[(3-PHENYL-5,6-DIHYDROIMIDAZO[1,2-A]PYRAZIN-7(8H)-YL)CARBONYL]THIOPHEN-2-YL}ETHANE-1,1-DIOL HDAC4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;HDAC4 43153:[DB06314 DB01496] DB06314|SGX-523 MET DB01496|Barbituric acid derivative GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GRIA2;MET;GABRA5;CHRNA7;CHRNA4;GABRA6 43154:[DB06314 DB04948] DB06314|SGX-523 MET DB04948|Lofexidine ADRA2A;ADRA1A;HTR1A;HTR7;HTR2C;HTR1D;CYP2D6;CYP1A2;CYP2C19;ABCB5;SLC47A1 common genes common pathways GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation MET;HTR1A GO:0007165| signal transduction ADRA1A;HTR1A;HTR1D;ADRA2A;HTR2C;MET;HTR7 GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET 43155:[DB06314 DB11637] DB06314|SGX-523 MET DB11637|Delamanid CYP3A4;ALB;ORM1 common genes common pathways 43156:[DB06314 DB13994] DB06314|SGX-523 MET DB13994|AZD-7325 GABRA3;GABRA2 common genes common pathways 43157:[DB06314 DB00414] DB06314|SGX-523 MET DB00414|Acetohexamide KCNJ1;CBR1;CYP2C9;ALB common genes common pathways 43158:[DB06314 DB00565] DB06314|SGX-523 MET DB00565|Cisatracurium CHRNA2 common genes common pathways GO:0007165| signal transduction CHRNA2;MET 43159:[DB06314 DB08502] DB06314|SGX-523 MET DB08502|Capravirine CYP3A4 common genes common pathways 43160:[DB06314 DB00494] DB06314|SGX-523 MET DB00494|Entacapone COMT;COMT;UGT1A9;CYP2D6 common genes common pathways 43161:[DB06314 DB01548] DB06314|SGX-523 MET DB01548|Diprenorphine OPRM1;OPRD1;OPRK1;TRIM13 common genes common pathways GO:0007165| signal transduction MET;OPRK1;OPRM1;TRIM13;OPRD1 43162:[DB06314 DB06148] DB06314|SGX-523 MET DB06148|Mianserin ADRA2A;HTR2A;HTR2C;HRH1;SLC6A2;SLC6A4;HRH4;HTR1A;ADRA2C;HTR2B;HTR1F;ADRA2B;DRD3;OPRK1;SLC6A3;HTR7;DRD2;HTR6;ADRA1A;ADRA1B;ADRA1D;DRD1;DRD5;CYP2D6;CYP3A4;CYP1A2;CYP2B6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;MET;DRD2 GO:0007165| signal transduction ADRA1A;DRD2;DRD1;HTR2A;ADRA2B;HTR2B;ADRA1B;HTR1A;HTR1F;HTR6;HTR2C;ADRA2A;HRH4;ADRA2C;HRH1;MET;OPRK1;HTR7;DRD3;ADRA1D;DRD5 GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0016310| phosphorylation HTR2B;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B;HTR1A GO:0010507| negative regulation of autophagy MET;HTR2B;ADRA1A 43163:[DB06314 DB12093] DB06314|SGX-523 MET DB12093|Tetrahydropalmatine DRD1;DRD2;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0007165| signal transduction DRD1;DRD2;MET 43164:[DB06314 DB00315] DB06314|SGX-523 MET DB00315|Zolmitriptan HTR1B;HTR1D;HTR1F;HTR1A;CYP1A2;MAOA common genes common pathways GO:0007165| signal transduction HTR1D;HTR1A;MET;HTR1F;HTR1B GO:0008283| cell proliferation HTR1A;MET 43165:[DB06314 DB11064] DB06314|SGX-523 MET DB11064|Homosalate PGR;AR;ESR1 common genes common pathways GO:0007165| signal transduction AR;PGR;MET;ESR1 GO:0008283| cell proliferation MET;AR GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET;PGR;AR 43166:[DB06314 DB07720] DB06314|SGX-523 MET DB07720|Epibatidine CHRFAM7A;CHRNA7;CHRNB2;CHRNA2;CHRNA3;CHRNA4;CHRNB4 common genes common pathways GO:0007165| signal transduction CHRNA3;CHRNB4;CHRNB2;MET;CHRFAM7A;CHRNA2;CHRNA7;CHRNA4 43167:[DB06314 DB05201] DB06314|SGX-523 MET DB05201|V24343 CNR1 common genes common pathways GO:0007165| signal transduction MET;CNR1 43168:[DB06314 DB03566] DB06314|SGX-523 MET DB03566|Spermidine TXNRD1;ADRB1;ADRB2;SLC22A4;SLC22A1 common genes common pathways GO:0008283| cell proliferation MET;TXNRD1 GO:0007165| signal transduction ADRB1;MET;ADRB2;TXNRD1 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 43169:[DB06314 DB09331] DB06314|SGX-523 MET DB09331|Daratumumab CD38 common genes common pathways GO:0007165| signal transduction MET;CD38 43170:[DB06314 DB06111] DB06314|SGX-523 MET DB06111|AB192 MPO common genes common pathways 43171:[DB06314 DB01074] DB06314|SGX-523 MET DB01074|Perhexiline CPT1A;CPT2;KCNH2;CYP2D6;CYP2B6;CYP3A4 common genes common pathways 43172:[DB06314 DB05091] DB06314|SGX-523 MET DB05091|M0002 AVPR2 common genes common pathways GO:0007165| signal transduction AVPR2;MET 43173:[DB06314 DB06595] DB06314|SGX-523 MET DB06595|Midostaurin PRKCA;KDR;KIT;PDGFRA;PDGFRB;FLT3;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP2E1;CYP3A4;CYP3A5;CYP3A7;CYP3A43 common genes common pathways GO:0006468| protein phosphorylation PDGFRA;KIT;KDR;FLT3;MET;PDGFRB;PRKCA GO:0016310| phosphorylation KDR;KIT;PDGFRA;PRKCA;PDGFRB;FLT3;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway PDGFRA;KDR;KIT;MET;FLT3;PDGFRB GO:0007165| signal transduction KIT;MET;PDGFRB GO:0018108| peptidyl-tyrosine phosphorylation PDGFRB;FLT3;MET;KIT;KDR;PDGFRA GO:0000165| MAPKKK cascade KIT;PDGFRA;PDGFRB;MET GO:0046854| phosphatidylinositol phosphorylation PDGFRB;MET;KIT;PDGFRA GO:0051897| positive regulation of protein kinase B signaling cascade PDGFRB;MET;KIT;PDGFRA 43174:[DB06314 DB00790] DB06314|SGX-523 MET DB00790|Perindopril ACE;SFRP4;BCHE;SLC15A1;SLC15A2 common genes common pathways 43175:[DB06314 DB01296] DB06314|SGX-523 MET DB01296|Glucosamine MMP9;NFKB2;TNF;IFNG;CYP2C19;CYP2E1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NFKB2;TNF GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF GO:0007165| signal transduction MET;NFKB2 GO:0007166| cell surface receptor linked signaling pathway IFNG;MET GO:0000165| MAPKKK cascade MET;TNF 43176:[DB06314 DB12866] DB06314|SGX-523 MET DB12866|Pradigastat SLC22A8 common genes common pathways 43177:[DB06314 DB00849] DB06314|SGX-523 MET DB00849|Methylphenobarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;NR1I2;CYP2C19;CYP2B6 common genes common pathways GO:0007165| signal transduction GRIA2;MET;NR1I2;GABRA5;CHRNA4;CHRNA7;GABRA6 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2 43178:[DB06314 DB01412] DB06314|SGX-523 MET DB01412|Theobromine ADORA1;ADORA2A;PDE4B;CYP1A2;CYP2E1 common genes common pathways GO:0007165| signal transduction PDE4B;ADORA2A;MET;ADORA1 43179:[DB06314 DB04674] DB06314|SGX-523 MET DB04674|2-HYDROXY-3,5-DIIODOBENZOIC ACID EDNRA;AKR1C1;TTR common genes common pathways GO:0007165| signal transduction EDNRA;MET GO:0008283| cell proliferation MET;EDNRA 43180:[DB06314 DB04827] DB06314|SGX-523 MET DB04827|Urethane PLA2G4A;MPO;AOX1 common genes common pathways 43181:[DB06314 DB00521] DB06314|SGX-523 MET DB00521|Carteolol ADRB2;ADRB1;CYP2D6 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction ADRB2;MET;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43182:[DB06314 DB00549] DB06314|SGX-523 MET DB00549|Zafirlukast CYSLTR1;CYP2C9;CYP2C8;PTGS1;CYP3A4;CYP1A2;CYP2C19;CYP2E1;ABCG2 common genes common pathways GO:0007165| signal transduction CYSLTR1;MET GO:0007166| cell surface receptor linked signaling pathway CYSLTR1;MET 43183:[DB06314 DB00531] DB06314|SGX-523 MET DB00531|Cyclophosphamide NR1I2;CYP2C9;CYP3A4;CYP2B6;CYP2C19;CYP2A6;CYP2C18;CYP2C8;CYP3A5 common genes common pathways GO:0007165| signal transduction MET;NR1I2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET 43184:[DB06314 DB05419] DB06314|SGX-523 MET DB05419|ADX-10061 CALY common genes common pathways 43185:[DB06314 DB06700] DB06314|SGX-523 MET DB06700|Desvenlafaxine SLC6A4;SLC6A2;CYP3A4 common genes common pathways 43186:[DB06314 DB00852] DB06314|SGX-523 MET DB00852|Pseudoephedrine SLC6A2;SLC6A3;ADRA1A;ADRA2A;SLC6A4;ADRB2;ADRB1;NFATC1;TNF;ATF1;ATF2;ATF3;ATF4;ATF5;ATF6;ATF7;JDP2;FOS;JUN;IL2;MAOA;CYP2D6 common genes common pathways GO:0000165| MAPKKK cascade TNF;IL2;MET GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0007165| signal transduction ADRB1;ADRA1A;ATF6;ADRB2;MET;ADRA2A GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0051897| positive regulation of protein kinase B signaling cascade TNF;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ATF1;JUN;ATF4;FOS;ATF3;TNF;MET;ADRB2;IL2;NFATC1;ATF2;ATF5;ATF6 43187:[DB06314 DB06769] DB06314|SGX-523 MET DB06769|Bendamustine CYP1A2 common genes common pathways 43188:[DB06314 DB05022] DB06314|SGX-523 MET DB05022|Amonafide TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 43189:[DB06314 DB00192] DB06314|SGX-523 MET DB00192|Indecainide SCN5A common genes common pathways 43190:[DB06314 DB00534] DB06314|SGX-523 MET DB00534|Chlormerodrin SLC12A1;ALDH5A1 common genes common pathways 43191:[DB06314 DB00229] DB06314|SGX-523 MET DB00229|Cefotiam SLC22A6;SLC22A8 common genes common pathways 43192:[DB06314 DB05210] DB06314|SGX-523 MET DB05210|SF1126 PIK3R1;PIK3R2;PIK3R3;PRKDC;MTOR common genes common pathways GO:0007165| signal transduction MTOR;PIK3R1;PIK3R2;MET GO:0006468| protein phosphorylation MET;MTOR;PIK3R1;PRKDC GO:0016310| phosphorylation MET;MTOR;PRKDC GO:0010507| negative regulation of autophagy MTOR;MET GO:0008283| cell proliferation PRKDC;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PIK3R2;PRKDC;PIK3R1 GO:0051897| positive regulation of protein kinase B signaling cascade PIK3R2;MET;PIK3R1;MTOR GO:0046854| phosphatidylinositol phosphorylation PIK3R2;MET;PIK3R1 43193:[DB06314 DB01588] DB06314|SGX-523 MET DB01588|Prazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRB3;MET;GABRP;GABRE;GABRQ;GABRA5;GABRD;GABRR2;GABRA6;GABRB1 43194:[DB06314 DB00963] DB06314|SGX-523 MET DB00963|Bromfenac PTGS2;PTGS1;PTGS2 common genes common pathways 43195:[DB06314 DB00396] DB06314|SGX-523 MET DB00396|Progesterone PGR;ESR1;NR3C2;CYP17A1;OPRK1;NR1I2;ORM1;NR3C1;AR;SHBG;CYP3A5;CYP2C9;CYP3A7;CYP2C19;CYP3A4;CYP17A1;CYP1A1;CYP1B1;CYP2A6;CYP2C8;CYP2D6;ABCB1;SLC22A2;SLC22A1;SLC22A3;ABCB11;ABCC1;SLC10A1;SLCO1B1;ABCG2 common genes common pathways GO:0007165| signal transduction ESR1;OPRK1;MET;NR1I2;NR3C1;PGR;NR3C2;AR GO:0008283| cell proliferation MET;AR;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;PGR;AR;ESR1;MET;NR1I2 43196:[DB06314 DB06138] DB06314|SGX-523 MET DB06138|IRL-1620 EDNRB common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;EDNRB GO:0007165| signal transduction MET;EDNRB 43197:[DB06314 DB00289] DB06314|SGX-523 MET DB00289|Atomoxetine SLC6A2;SLC6A4;SLC6A3;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP2D6;CYP2C19;CYP3A4 common genes common pathways GO:0000165| MAPKKK cascade GRIN2D;MET;GRIN2A;GRIN2B;GRIN1;GRIN2C GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;MET 43198:[DB06314 DB00946] DB06314|SGX-523 MET DB00946|Phenprocoumon VKORC1;CYP2C8;CYP2C9;CYP3A4;ALB;ORM1 common genes common pathways 43199:[DB06314 DB11491] DB06314|SGX-523 MET DB11491|Sarafloxacin CYP1A2 common genes common pathways 43200:[DB06314 DB06751] DB06314|SGX-523 MET DB06751|Drotaverine PDE4A;CACNA1C common genes common pathways GO:0007165| signal transduction MET;PDE4A 43201:[DB06314 DB04926] DB06314|SGX-523 MET DB04926|Neramexane GRIN3A common genes common pathways 43202:[DB06314 DB01650] DB06314|SGX-523 MET DB01650|trans-2-hydroxycinnamic acid SLC22A8 common genes common pathways 43203:[DB06314 DB05521] DB06314|SGX-523 MET DB05521|Telaprevir SLCO1B1;SLCO2B1;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways 43204:[DB06314 DB01257] DB06314|SGX-523 MET DB01257|Eculizumab C5 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;C5 43205:[DB06314 DB00150] DB06314|SGX-523 MET DB00150|L-Tryptophan WARS2;trpS;WARS;TDO2;DDC;trpS;WARS2;TPH1;TPH2;WARS;IDO1;SLC16A2;SLC16A10 common genes common pathways 43206:[DB06314 DB12035] DB06314|SGX-523 MET DB12035|Sarecycline ABCB1 common genes common pathways 43207:[DB06314 DB11577] DB06314|SGX-523 MET DB11577|Indigotindisulfonic Acid AHR;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;AHR GO:0007165| signal transduction ADRA2C;MET;ADRA2A;ADRA1D;ADRA2B;ADRA1A;ADRA1B GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B 43208:[DB06314 DB01288] DB06314|SGX-523 MET DB01288|Fenoterol ADRB2;ADRB1;ADRB3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction ADRB2;MET;ADRB3;ADRB1 43209:[DB06314 DB08827] DB06314|SGX-523 MET DB08827|Lomitapide MTTP;CYP3A4;ABCB1 common genes common pathways 43210:[DB06314 DB06155] DB06314|SGX-523 MET DB06155|Rimonabant CNR1;GPR55;CYP3A4 common genes common pathways GO:0007165| signal transduction GPR55;CNR1;MET 43211:[DB06314 DB06274] DB06314|SGX-523 MET DB06274|Alvimopan OPRM1;OPRK1;OPRD1 common genes common pathways GO:0007165| signal transduction MET;OPRM1;OPRK1;OPRD1 43212:[DB06314 DB11431] DB06314|SGX-523 MET DB11431|Moxidectin CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2B;ABCB1;ABCG2 common genes common pathways 43213:[DB06314 DB06292] DB06314|SGX-523 MET DB06292|Dapagliflozin SLC5A2;CYP1A1;CYP1A2;CYP2A6;CYP2C9;CYP2D6;CYP3A4;UGT1A9;UGT2B4;UGT2B7;ABCB1 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 43214:[DB06314 DB00715] DB06314|SGX-523 MET DB00715|Paroxetine SLC6A4;SLC6A2;HTR2A;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2D6;CYP2C9;CYP2B6;CYP2C8;CYP1A2;CYP3A4;ABCB1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0008283| cell proliferation MET;CHRM5;CHRM3;CHRM1;CHRM4 GO:0007165| signal transduction CHRM4;CHRM1;CHRM3;CHRM5;MET;CHRM2;HTR2A 43215:[DB06314 DB05688] DB06314|SGX-523 MET DB05688|CRx-119 SLC6A4;SLC6A2;SERPINA6 common genes common pathways 43216:[DB06314 DB00567] DB06314|SGX-523 MET DB00567|Cephalexin CYP3A4;ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC47A1;SLC22A8 common genes common pathways 43217:[DB06314 DB04958] DB06314|SGX-523 MET DB04958|Epratuzumab CD22 common genes common pathways 43218:[DB06314 DB01483] DB06314|SGX-523 MET DB01483|Barbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;CYP3A4;CYP2C19 common genes common pathways GO:0007165| signal transduction GABRA6;CHRNA4;CHRNA7;GABRA5;MET;GRIA2 43219:[DB06314 DB00130] DB06314|SGX-523 MET DB00130|L-Glutamine CTPS1;PPAT;GLUL;F13A1;GLS;GLS2;TGM2;TGM5;TGM6;TGM1;TGM4;TGM3;TGM7;GMPS;ASNS;CCBL1;PFAS;GATB;GFPT2;CAD;QARS;NADSYN1;SLC16A10;SLC38A3;SLC1A5;SLC7A8 common genes common pathways GO:0008283| cell proliferation GLUL;MET 43220:[DB06314 DB06579] DB06314|SGX-523 MET DB06579|Adipiplon GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3 common genes common pathways GO:0007165| signal transduction MET;GABRA5;GABRA6 43221:[DB06314 DB00834] DB06314|SGX-523 MET DB00834|Mifepristone PGR;NR3C1;KLK3;NR1I2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP2C8;CYP2C9;ABCB1;ABCC1;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET;PGR;NR3C1 GO:0007165| signal transduction MET;NR1I2;NR3C1;PGR 43222:[DB06314 DB14069] DB06314|SGX-523 MET DB14069|ONT-093 ABCB1 common genes common pathways 43223:[DB06314 DB01551] DB06314|SGX-523 MET DB01551|Dihydrocodeine CYP2D6;CYP3A4 common genes common pathways 43224:[DB06314 DB00978] DB06314|SGX-523 MET DB00978|Lomefloxacin parC;gyrA;TOP2A;CYP1A2;SLC22A5;ABCC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43225:[DB06314 DB06714] DB06314|SGX-523 MET DB06714|Propylhexedrine SLC18A2;TAAR1 common genes common pathways GO:0007165| signal transduction MET;TAAR1 43226:[DB06314 DB05034] DB06314|SGX-523 MET DB05034|Ularitide NPR1 common genes common pathways GO:0006468| protein phosphorylation NPR1;MET GO:0007166| cell surface receptor linked signaling pathway NPR1;MET 43227:[DB06314 DB06603] DB06314|SGX-523 MET DB06603|Panobinostat HDAC1;HDAC10;HDAC11;HDAC2;HDAC3;HDAC4;HDAC5;HDAC6;HDAC7;HDAC8;HDAC9;CYP2D6;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter HDAC2;HDAC1;HDAC3;HDAC5;HDAC4;MET 43228:[DB06314 DB09030] DB06314|SGX-523 MET DB09030|Vorapaxar F2R;CYP3A4;CYP2J2 common genes common pathways GO:0007165| signal transduction F2R;MET 43229:[DB06314 DB06342] DB06314|SGX-523 MET DB06342|Coltuximab ravtansine CD19;CYP3A4 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade CD19;MET GO:0046854| phosphatidylinositol phosphorylation MET;CD19 GO:0007166| cell surface receptor linked signaling pathway MET;CD19 43230:[DB06314 DB04299] DB06314|SGX-523 MET DB04299|Maleic Acid GOT1;TPR;tyrB common genes common pathways 43231:[DB06314 DB00529] DB06314|SGX-523 MET DB00529|Foscarnet SLC22A6;SLC16A1 common genes common pathways 43232:[DB06314 DB07194] DB06314|SGX-523 MET DB07194|2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide SYK common genes common pathways GO:0008283| cell proliferation MET;SYK GO:0016310| phosphorylation MET;SYK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;SYK GO:0006468| protein phosphorylation MET;SYK GO:0007166| cell surface receptor linked signaling pathway SYK;MET GO:0018108| peptidyl-tyrosine phosphorylation SYK;MET 43233:[DB06314 DB09108] DB06314|SGX-523 MET DB09108|Simoctocog Alfa VWF common genes common pathways 43234:[DB06314 DB00537] DB06314|SGX-523 MET DB00537|Ciprofloxacin parC;gyrA;TOP2A;KCNH2;gyrA;parC;parE;gyrA;gyrA;CYP3A4;CYP3A5;CYP3A7;CYP1A2;ABCB1;SLC47A1;SLC47A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43235:[DB06314 DB00713] DB06314|SGX-523 MET DB00713|Oxacillin SLC15A1;SLC15A2;SLC15A1;SLC15A2 common genes common pathways 43236:[DB06314 DB14055] DB06314|SGX-523 MET DB14055|(S)-Warfarin CYP3A4;CYP2C8;CYP2C9;CYP2C18;CYP2C19 common genes common pathways 43237:[DB06314 DB00305] DB06314|SGX-523 MET DB00305|Mitomycin POR common genes common pathways 43238:[DB06314 DB09195] DB06314|SGX-523 MET DB09195|Lorpiprazole HTR2A;HTR2C;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;HRH1;SLC6A4;CYP2D6;CYP3A4;ALB common genes common pathways GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation ADRA1B;ADRA1D;MET GO:0007165| signal transduction ADRA1D;ADRA2A;HTR2C;ADRA2C;MET;HRH1;ADRA1B;ADRA1A;ADRA2B;HTR2A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET 43239:[DB06314 DB01047] DB06314|SGX-523 MET DB01047|Fluocinonide NR3C1;SMO;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;SMO;MET GO:0007165| signal transduction NR3C1;SMO;MET GO:0007166| cell surface receptor linked signaling pathway MET;SMO 43240:[DB06314 DB00501] DB06314|SGX-523 MET DB00501|Cimetidine HRH2;CYP1A2;CYP2C19;CYP3A4;CYP3A5;CYP3A7;CYP2D6;CYP11B1;CYP2C8;CYP2C9;CYP2E1;FMO3;FMO1;ABCB1;SLC22A2;SLC22A1;SLC22A3;SLC22A5;SLC22A6;SLC22A8;SLC47A1;SLC22A4;SLC22A11;SLC22A7;ABCB11;SLC47A2 common genes common pathways GO:0007165| signal transduction HRH2;MET 43241:[DB06314 DB00619] DB06314|SGX-523 MET DB00619|Imatinib BCR/ABL fusion;KIT;RET;NTRK1;CSF1R;PDGFRA;DDR1;ABL1;PDGFRB;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2D6;CYP2C19;PTGS1;ALB;ORM1;SLC22A1;ABCB1;SLC22A2;ABCG2;ABCA3;ABCB11 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation KIT;PDGFRA;PDGFRB;MET GO:0051897| positive regulation of protein kinase B signaling cascade KIT;PDGFRA;PDGFRB;MET GO:0008283| cell proliferation CSF1R;MET GO:0007165| signal transduction PDGFRB;MET;KIT;CSF1R;RET GO:0006468| protein phosphorylation PDGFRB;MET;ABL1;NTRK1;CSF1R;KIT;DDR1;RET;PDGFRA GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway DDR1;KIT;CSF1R;PDGFRA;RET;PDGFRB;NTRK1;MET GO:0016310| phosphorylation PDGFRB;MET;ABL1;NTRK1;KIT;CSF1R;DDR1;RET;PDGFRA GO:0000165| MAPKKK cascade KIT;PDGFRA;RET;PDGFRB;MET GO:0018108| peptidyl-tyrosine phosphorylation MET;ABL1;NTRK1;PDGFRB;RET;PDGFRA;KIT;CSF1R;DDR1 43242:[DB06314 DB01263] DB06314|SGX-523 MET DB01263|Posaconazole CYP3A4;ABCB1 common genes common pathways 43243:[DB06314 DB08904] DB06314|SGX-523 MET DB08904|Certolizumab pegol TNF common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF GO:0000165| MAPKKK cascade MET;TNF 43244:[DB06314 DB08882] DB06314|SGX-523 MET DB08882|Linagliptin DPP4;CYP3A4;ABCB1 common genes common pathways 43245:[DB06314 DB08900] DB06314|SGX-523 MET DB08900|Teduglutide GLP2R common genes common pathways GO:0007165| signal transduction GLP2R;MET GO:0007166| cell surface receptor linked signaling pathway MET;GLP2R 43246:[DB06314 DB13167] DB06314|SGX-523 MET DB13167|Alclofenac PTGS2 common genes common pathways 43247:[DB06314 DB00182] DB06314|SGX-523 MET DB00182|Amphetamine SLC18A2;SLC6A3;CARTPT;TAAR1;SLC6A2;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;DRD2;MAOB;SLC6A4;MAOA;MAOB;VMAT2;CYP2D6;CYP2A6;SLC22A3;SLC22A5 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0007165| signal transduction CARTPT;MET;ADRB2;ADRA2C;ADRA2A;ADRA1D;ADRA2B;ADRA1A;DRD2;ADRB3;ADRA1B;ADRB1;TAAR1 GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET;DRD2 43248:[DB06314 DB00921] DB06314|SGX-523 MET DB00921|Buprenorphine OPRM1;OPRK1;OPRD1;OPRL1;CYP3A4;CYP3A5;CYP2C9;CYP2C8;CYP3A7;UGT1A9;CYP2D6;CYP2C18;CYP2C19;CYP2A6;UGT1A1;ABCB1;ABCG2 common genes common pathways GO:0007165| signal transduction OPRD1;MET;OPRL1;OPRM1;OPRK1 43249:[DB06314 DB01590] DB06314|SGX-523 MET DB01590|Everolimus MTOR;CYP3A4;SLCO1B1;SLCO1B3;SLCO1A2 common genes common pathways GO:0010507| negative regulation of autophagy MET;MTOR GO:0016310| phosphorylation MTOR;MET GO:0006468| protein phosphorylation MTOR;MET GO:0007165| signal transduction MTOR;MET GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;MET 43250:[DB06314 DB00661] DB06314|SGX-523 MET DB00661|Verapamil CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1I;CACNA1G;CACNA1B;CACNA1A;KCNH2;SCN5A;KCNJ11;SLC6A4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A5;CYP3A7;CYP1A2;CYP2C9;CYP2C8;CYP2C19;CYP2C18;CYP2B6;CYP2D6;ABCB1;SLC22A1;ABCC3;ABCC4;SLC22A5;ABCC1;SLCO1A2;ABCC10;ABCC2;SLC22A4;ABCG2;SLCO1B1;ABCB11 common genes common pathways GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation MET;ADRA1D;ADRA1B GO:0007165| signal transduction ADRA1D;CACNA1I;MET;ADRA1B;ADRA1A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET 43251:[DB06314 DB01367] DB06314|SGX-523 MET DB01367|Rasagiline MAOB;BCL2;CYP1A2 common genes common pathways GO:0010507| negative regulation of autophagy MET;BCL2 GO:0008283| cell proliferation MET;BCL2 43252:[DB06314 DB01307] DB06314|SGX-523 MET DB01307|Insulin Detemir INSR;ALB common genes common pathways GO:0006468| protein phosphorylation MET;INSR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway INSR;MET GO:0016310| phosphorylation INSR;MET GO:0018108| peptidyl-tyrosine phosphorylation INSR;MET GO:0051897| positive regulation of protein kinase B signaling cascade INSR;MET 43253:[DB06314 DB01571] DB06314|SGX-523 MET DB01571|3-Methylfentanyl OPRM1;OPRD1;OPRK1 common genes common pathways GO:0007165| signal transduction MET;OPRM1;OPRK1;OPRD1 43254:[DB06314 DB00353] DB06314|SGX-523 MET DB00353|Methylergometrine DRD1;HTR2B;CYP3A4 common genes common pathways GO:0016310| phosphorylation HTR2B;MET GO:0007165| signal transduction HTR2B;DRD1;MET GO:0010507| negative regulation of autophagy HTR2B;MET 43255:[DB06314 DB01408] DB06314|SGX-523 MET DB01408|Bambuterol ADRB2;BCHE common genes common pathways GO:0007165| signal transduction MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 43256:[DB06314 DB08820] DB06314|SGX-523 MET DB08820|Ivacaftor CFTR;CYP3A4;CYP3A5;ALB;ORM1;ABCB1 common genes common pathways 43257:[DB06314 DB00324] DB06314|SGX-523 MET DB00324|Fluorometholone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction MET;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 43258:[DB06314 DB04938] DB06314|SGX-523 MET DB04938|Ospemifene ESR1;CYP3A4;CYP2C9;CYP2C19;CYP2B6;CYP2D6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET GO:0007165| signal transduction ESR1;MET 43259:[DB06314 DB13878] DB06314|SGX-523 MET DB13878|Pibrentasvir CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A1;ABCB1;ABCG2;SLCO1B1;SLCO1B3 common genes common pathways 43260:[DB06314 DB13961] DB06314|SGX-523 MET DB13961|Fish oil DGAT2;PTGS2;FFAR4;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NFKB2;NFKB1;SREBF1;PPARA;PPARG;PPARD;CYP3A4 common genes common pathways GO:0007165| signal transduction NFKB1;NFKB2;MET;PPARG;FFAR4 GO:0008283| cell proliferation MET;PPARD GO:0045944| positive regulation of transcription from RNA polymerase II promoter NFKB1;SREBF1;NFKB2;MET;PPARG;PPARA 43261:[DB06314 DB00261] DB06314|SGX-523 MET DB00261|Anagrelide PDE3A;CYP1A2 common genes common pathways GO:0007165| signal transduction PDE3A;MET 43262:[DB06314 DB00444] DB06314|SGX-523 MET DB00444|Teniposide TOP2A;CYP3A4;CYP2C9;CYP2C19;CYP3A5;ABCC6;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 43263:[DB06314 DB01942] DB06314|SGX-523 MET DB01942|Formic Acid HMOX1;RNASE1;pyrD;bla;ffh;CTBP1;pgl;CASK;gmk;GGACT;PVALB;ACYP2;NOS1;GPHN;CYTH2;moaE;fbpA;gyrB;hemB;aroA;FGF1;def;CA2;SLC16A3 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation FGF1;MET GO:0051897| positive regulation of protein kinase B signaling cascade FGF1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter CASK;NOS1;FGF1;MET GO:0008283| cell proliferation FGF1;MET GO:0007165| signal transduction FGF1;MET GO:0016310| phosphorylation CASK;MET GO:0006468| protein phosphorylation CASK;MET;CTBP1 GO:0000165| MAPKKK cascade MET;FGF1 GO:0018108| peptidyl-tyrosine phosphorylation FGF1;MET 43264:[DB06314 DB01098] DB06314|SGX-523 MET DB01098|Rosuvastatin HMGCR;CYP2C9;CYP2C19;CYP3A4;CYP3A5;ALB;ABCC1;ABCC4;SLCO1A2;SLCO1B1;SLCO1B3;SLCO2B1;SLC7A11;ABCB11;ABCG2;ABCC2;SLC22A8 common genes common pathways 43265:[DB06314 DB13508] DB06314|SGX-523 MET DB13508|Cloranolol CYP2D6 common genes common pathways 43266:[DB06314 DB01236] DB06314|SGX-523 MET DB01236|Sevoflurane GABRA1;GLRA1;GRIA1;KCNA1;ATP2C1;MT-ND1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2E1;CYP2A6;CYP2B6;CYP3A4;ALB common genes common pathways GO:0007165| signal transduction GABRA6;GABRB1;GABRD;GABRA5;GABRE;GABRQ;ATP2C1;GABRP;GRIA1;MET;GABRB3 43267:[DB06314 DB09481] DB06314|SGX-523 MET DB09481|Magnesium carbonate GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;TRPM6;SLC41A3;CNNM2;TRPM7 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;GRIN1 GO:0000165| MAPKKK cascade GRIN2B;GRIN2A;MET;GRIN2D;GRIN2C;GRIN1 GO:0006468| protein phosphorylation MET;TRPM6;TRPM7 GO:0016310| phosphorylation TRPM7;MET;TRPM6 43268:[DB06314 DB02489] DB06314|SGX-523 MET DB02489|9-Methylguanine folB;CYP1A2 common genes common pathways 43269:[DB06314 DB13954] DB06314|SGX-523 MET DB13954|Estradiol cypionate ESR1;NR1I2;ESR2;CHRNA4;NCOA2;GPER1;MT-ATP6;BECN1;HSD17B2;ESRRG;CYP1A2;UGT1A1;CYP3A4;CYP3A5;CYP3A7;CYP1A1;CYP1B1;CYP2C19;CYP2C8;CYP2C9;SHBG;ALB;FABP2;SLC22A2;SLC22A1;SLC22A3;SLCO2B1;SLCO1A2;ABCC10;SLC22A11;ABCG2;SLCO1B1;ABCB1;SLC22A8;SLCO1B3;SLCO1C1;SLCO4A1 common genes common pathways GO:0007165| signal transduction CHRNA4;MET;NR1I2;ESR1;GPER1;ESR2 GO:0008283| cell proliferation MET;CYP1A1 GO:0010507| negative regulation of autophagy BECN1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2;ESR1;GPER1;ESR2;NCOA2;ESRRG 43270:[DB06314 DB04365] DB06314|SGX-523 MET DB04365|Arecoline CHRM1;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM3;MET;CHRM1 GO:0008283| cell proliferation CHRM3;MET;CHRM1 43271:[DB06314 DB01593] DB06314|SGX-523 MET DB01593|Zinc BDKRB1;MGMT;ALDOA;EEF1A1;ENO1;GAPDHS;NME1;P4HB;PDIA3;PRDX1;PSPH;TPI1;TUFM;ESR1;IL3;MT2A;CCS;HDAC1;HDAC4;MPG;SEMG1;SOD1;HDAC8;SIVA1;GLRA1;MDM2;INS;UTRN;ASPA;S100A8;S100A9;MMP9;TP73;S100A2;TP53;MT3;PDCD6;DAND5;MT1A;A1BG;A2M;AGT;AHSG;APCS;APOA1;APOA2;APOA4;APOBR;APOE;APOL1;C1QB;C1QC;C1R;C1S;C3;C4B;C4BPA;C4BPB;C5;BRCC3;C8A;C8B;C8G;CFB;CFH;CFI;CLU;CP;CPN1;CPN2;DCD;DSP;F12;F13B;F2;FCN3;FGA;FN1;GSN;HBA1;HBB;HPR;HRNR;IGFALS;IGHA1;IGHM;IGKV1-17;IGLV3-21;ITIH1;ITIH2;ITIH3;ITIH4;JCHAIN;JUP;KLKB1;KNG1;KRT1;KRT10;KRT14;KRT16;KRT2;KRT5;KRT6A;KRT9;ORM2;PGLYRP2;PON1;PZP;S100A7;SEPP1;SERPINA1;SERPINA3;SERPINA4;SERPINA6;SERPIND1;SHBG;TF;TTR;VTN;APLP1;APLP2;APP;PARP1;CA1;CPE;ADH1C;IDE;SOD1 common genes common pathways GO:0000165| MAPKKK cascade INS;MET;IL3 GO:0061436| MET;HRNR;KRT16;KRT1 GO:0018108| peptidyl-tyrosine phosphorylation MET;IL3 GO:0007166| cell surface receptor linked signaling pathway MET;AGT;C5;F2 GO:0010507| negative regulation of autophagy MET;MT3 GO:0008283| cell proliferation TP53;MT3;KRT16;PRDX1;MET GO:0007165| signal transduction JUP;MET;IGFALS;ESR1;BDKRB1;PDIA3;C3;FGA GO:0006468| protein phosphorylation APP;MET GO:0016310| phosphorylation NME1;MET GO:0051897| positive regulation of protein kinase B signaling cascade APP;INS;MET GO:0050918| positive chemotaxis APP;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter TP73;HDAC1;TP53;APP;ESR1;PARP1;HDAC4;MET 43272:[DB06314 DB00075] DB06314|SGX-523 MET DB00075|Muromonab CD3D;CD3E;CD3G;CD247;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;CD3E GO:0007165| signal transduction FCGR1A;MET;FCGR2B;FCGR2C GO:0007166| cell surface receptor linked signaling pathway MET;CD3E;CD247;CD3D;CD3G GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;CD3D 43273:[DB06314 DB09063] DB06314|SGX-523 MET DB09063|Ceritinib ALK;CYP2C9;CYP3A4;ABCB1 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation ALK;MET GO:0007165| signal transduction MET;ALK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;ALK GO:0016310| phosphorylation MET;ALK GO:0006468| protein phosphorylation ALK;MET GO:0008283| cell proliferation MET;ALK 43274:[DB06314 DB00607] DB06314|SGX-523 MET DB00607|Nafcillin CYP3A4;CYP1A2;ALB;SLC22A6 common genes common pathways 43275:[DB06314 DB05932] DB06314|SGX-523 MET DB05932|Denibulin VEGFA;FLT1;FLT4 common genes common pathways GO:0048754| branching morphogenesis of a tube MET;VEGFA GO:0016310| phosphorylation FLT4;FLT1;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;FLT1;FLT4 GO:0006468| protein phosphorylation MET;FLT4;FLT1 GO:0018108| peptidyl-tyrosine phosphorylation FLT1;FLT4;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;VEGFA GO:0050918| positive chemotaxis MET;VEGFA 43276:[DB06314 DB06786] DB06314|SGX-523 MET DB06786|Halcinonide SMO;CYP3A4 common genes common pathways GO:0007165| signal transduction SMO;MET GO:0007166| cell surface receptor linked signaling pathway MET;SMO GO:0045944| positive regulation of transcription from RNA polymerase II promoter SMO;MET 43277:[DB06314 DB00514] DB06314|SGX-523 MET DB00514|Dextromethorphan SIGMAR1;SIGMAR1;GRIN3A;CHRNA2;SLC6A4;PGRMC1;CHRNA3;CHRNA4;CHRNB4;CHRNB2;CHRNA7;OPRM1;OPRD1;OPRK1;CYBB;CYBA;NCF1;NCF2;NCF4;RAC1;RAC2;SLC6A2;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2B6;CYP2C19;CYP2C9;CYP2C8;CYP2E1 common genes common pathways GO:0006468| protein phosphorylation RAC1;MET GO:0007165| signal transduction CHRNA3;CHRNB4;CHRNB2;MET;OPRK1;OPRM1;CHRNA2;RAC2;CHRNA7;CHRNA4;OPRD1 GO:0008283| cell proliferation RAC1;MET GO:0031116| positive regulation of microtubule polymerization RAC1;MET GO:0071526| semaphorin-plexin signaling pathway MET;RAC1 GO:0048012| hepatocyte growth factor receptor signaling pathway RAC1;MET 43278:[DB06314 DB01101] DB06314|SGX-523 MET DB01101|Capecitabine TYMS;TYMP;CES1;DPYD;CDA;CYP2C9 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CDA;MET 43279:[DB06314 DB13141] DB06314|SGX-523 MET DB13141|Ambroxol acefyllinate CYP3A4;CYP3A43;CYP3A5;CYP3A7 common genes common pathways 43280:[DB06314 DB13867] DB06314|SGX-523 MET DB13867|Fluticasone CYP3A4;CYP2C8;ABCB1;SLCO1B1 common genes common pathways 43281:[DB06314 DB01275] DB06314|SGX-523 MET DB01275|Hydralazine AOC3;P4HA1;CYP3A4 common genes common pathways 43282:[DB06314 DB12092] DB06314|SGX-523 MET DB12092|Naftopidil CYP3A4 common genes common pathways 43283:[DB06314 DB00134] DB06314|SGX-523 MET DB00134|Methionine MTRR;MTR;METAP2;BHMT;BHMT2;GLUL;MTHFR;MAT2A;MSRB2;MAT1A;MSRB1;MSRA;MARS;MARS2;MAT2B;SLC16A10 common genes common pathways GO:0008283| cell proliferation MET;GLUL 43284:[DB06314 DB02943] DB06314|SGX-523 MET DB02943|N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine GSTA1;GSTA1 common genes common pathways 43285:[DB06314 DB01327] DB06314|SGX-523 MET DB01327|Cefazolin mrcA;PON1;IL15;IL2;TPMT;ALB;ABCC4;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;IL2 GO:0000165| MAPKKK cascade IL2;MET GO:0007165| signal transduction IL15;MET 43286:[DB06314 DB07280] DB06314|SGX-523 MET DB07280|5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE ADK common genes common pathways GO:0016310| phosphorylation MET;ADK 43287:[DB06314 DB00342] DB06314|SGX-523 MET DB00342|Terfenadine HRH1;KCNH2;CHRM3;CHRM1;CHRM5;CHRM4;CHRM2;CYP3A4;CYP3A7;CYP2D6;CYP3A5;CYP2C8;CYP2J2;ABCB1;ABCB11 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0008283| cell proliferation CHRM4;CHRM1;CHRM3;MET;CHRM5 GO:0007165| signal transduction CHRM4;CHRM1;CHRM3;MET;CHRM5;HRH1;CHRM2 43288:[DB06314 DB00398] DB06314|SGX-523 MET DB00398|Sorafenib BRAF;RAF1;FLT4;KDR;FLT3;PDGFRB;KIT;FGFR1;RET;FLT1;CYP2C9;CYP3A5;CYP3A7;CYP3A4;CYP2B6;CYP2C8;CYP1A2;CYP2C19;CYP2D6;UGT1A9;UGT1A1;ABCG2;ABCC4;ABCC2;ABCB1;RALBP1;SLCO1B1 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation KIT;FGFR1;MET;PDGFRB GO:0051897| positive regulation of protein kinase B signaling cascade KIT;FGFR1;PDGFRB;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter RAF1;MET GO:0008283| cell proliferation RAF1;MET GO:0007165| signal transduction KIT;RALBP1;RAF1;RET;PDGFRB;BRAF;MET GO:0016310| phosphorylation KIT;FGFR1;KDR;FLT4;RET;RAF1;FLT1;BRAF;PDGFRB;FLT3;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway PDGFRB;MET;FLT3;KIT;FLT4;KDR;FLT1;RET GO:0006468| protein phosphorylation RET;FLT1;RAF1;KIT;FGFR1;KDR;FLT4;FLT3;MET;BRAF;PDGFRB GO:0000165| MAPKKK cascade KIT;FGFR1;RET;RAF1;BRAF;PDGFRB;MET GO:0018108| peptidyl-tyrosine phosphorylation PDGFRB;FLT3;MET;FLT4;KDR;FGFR1;KIT;FLT1;RET 43289:[DB06314 DB13923] DB06314|SGX-523 MET DB13923|Emicizumab F9;F10 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade F10;MET 43290:[DB06314 DB14061] DB06314|SGX-523 MET DB14061|Hycanthone ABCB1 common genes common pathways 43291:[DB06314 DB00112] DB06314|SGX-523 MET DB00112|Bevacizumab VEGFA;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0048754| branching morphogenesis of a tube VEGFA;MET GO:0007165| signal transduction FCGR2C;FCGR2B;MET;FCGR1A GO:0050918| positive chemotaxis VEGFA;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;VEGFA 43292:[DB06314 DB09034] DB06314|SGX-523 MET DB09034|Suvorexant HCRTR1;HCRTR2;CYP3A4 common genes common pathways GO:0007165| signal transduction HCRTR2;MET;HCRTR1 43293:[DB06314 DB01242] DB06314|SGX-523 MET DB01242|Clomipramine SLC6A4;HTR2A;HTR2B;HTR2C;SLC6A2;GSTP1;CYP2D6;CYP2C19;CYP1A2;CYP3A4;ALB;ABCB1 common genes common pathways GO:0010507| negative regulation of autophagy MET;HTR2B GO:0016310| phosphorylation HTR2B;MET GO:0007165| signal transduction HTR2C;MET;HTR2B;HTR2A 43294:[DB06314 DB06458] DB06314|SGX-523 MET DB06458|Remacemide CYP3A4 common genes common pathways 43295:[DB06314 DB07840] DB06314|SGX-523 MET DB07840|(E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol FGFR1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;FGFR1 GO:0046854| phosphatidylinositol phosphorylation FGFR1;MET GO:0018108| peptidyl-tyrosine phosphorylation MET;FGFR1 GO:0000165| MAPKKK cascade FGFR1;MET GO:0016310| phosphorylation FGFR1;MET GO:0006468| protein phosphorylation MET;FGFR1 43296:[DB06314 DB00470] DB06314|SGX-523 MET DB00470|Dronabinol CNR1;CNR2;CYP3A4;CYP2C9;CYP2C19;PTGS1;CYP1A1;CYP2A6;ABCB1;ABCG2 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 GO:0007165| signal transduction CNR2;MET;CNR1 43297:[DB06314 DB01295] DB06314|SGX-523 MET DB01295|Bevantolol ADRB1;ADRB2;ADRA1A;CYP2D6 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction ADRB2;MET;ADRB1;ADRA1A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43298:[DB06314 DB01336] DB06314|SGX-523 MET DB01336|Metocurine CHRNA2;CHRM2 common genes common pathways GO:0007165| signal transduction MET;CHRM2;CHRNA2 43299:[DB06314 DB06655] DB06314|SGX-523 MET DB06655|Liraglutide GLP1R;DPP4;MME common genes common pathways GO:0007165| signal transduction GLP1R;MET GO:0007166| cell surface receptor linked signaling pathway MET;GLP1R 43300:[DB06314 DB04539] DB06314|SGX-523 MET DB04539|Glyphosate aroA;aroA;CYP19A1;ALB common genes common pathways 43301:[DB06314 DB00559] DB06314|SGX-523 MET DB00559|Bosentan EDNRA;EDNRB;CYP3A4;CYP2C9;ABCB11 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway EDNRB;MET GO:0007165| signal transduction EDNRB;MET;EDNRA GO:0008283| cell proliferation EDNRA;MET 43302:[DB06314 DB00823] DB06314|SGX-523 MET DB00823|Ethynodiol diacetate PGR;ESR1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ESR1;PGR GO:0007165| signal transduction PGR;ESR1;MET 43303:[DB06314 DB05372] DB06314|SGX-523 MET DB05372|CP-945598 CNR1 common genes common pathways GO:0007165| signal transduction MET;CNR1 43304:[DB06314 DB00174] DB06314|SGX-523 MET DB00174|L-Asparagine SLC1A5;ASRGL1;NARS2;SLC38A3;ASNS;NARS;SLC16A10 common genes common pathways 43305:[DB06314 DB01154] DB06314|SGX-523 MET DB01154|Thiamylal GABRA1;KCNJ8;KCNJ11;CYP2C9;CYP3A4;CYP2E1 common genes common pathways 43306:[DB06314 DB01356] DB06314|SGX-523 MET DB01356|Lithium cation GSK3B;IMPA1;IMPA2;GRIA3 common genes common pathways GO:0046854| phosphatidylinositol phosphorylation IMPA2;MET;IMPA1 GO:0016310| phosphorylation MET;GSK3B GO:0006468| protein phosphorylation GSK3B;MET GO:0007165| signal transduction IMPA2;IMPA1;MET 43307:[DB06314 DB06779] DB06314|SGX-523 MET DB06779|Dalteparin SERPINC1;VEGFA;TFPI;SELP;HPSE common genes common pathways GO:0050918| positive chemotaxis VEGFA;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;HPSE GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;VEGFA GO:0048754| branching morphogenesis of a tube MET;VEGFA 43308:[DB06314 DB05501] DB06314|SGX-523 MET DB05501|AMD-070 CXCR4;CCR5 common genes common pathways GO:0007165| signal transduction MET;CCR5;CXCR4 GO:0007166| cell surface receptor linked signaling pathway CCR5;MET GO:0000165| MAPKKK cascade MET;CCR5 43309:[DB06314 DB06702] DB06314|SGX-523 MET DB06702|Fesoterodine CHRM3;CHRM4;CHRM1;CHRM2;CHRM5;CYP3A4;CYP2D6;ABCB1 common genes common pathways GO:0008283| cell proliferation CHRM5;MET;CHRM3;CHRM1;CHRM4 GO:0007165| signal transduction CHRM3;CHRM2;MET;CHRM5;CHRM4;CHRM1 GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET 43310:[DB06314 DB01426] DB06314|SGX-523 MET DB01426|Ajmaline SCN5A;ORM1 common genes common pathways 43311:[DB06314 DB00462] DB06314|SGX-523 MET DB00462|Methscopolamine bromide CHRM1;CHRM2;CHRM3 common genes common pathways GO:0007165| signal transduction CHRM1;MET;CHRM2;CHRM3 GO:0008283| cell proliferation CHRM1;CHRM3;MET 43312:[DB06314 DB04850] DB06314|SGX-523 MET DB04850|Posizolid MAOA;SLCO1B1 common genes common pathways 43313:[DB06314 DB06266] DB06314|SGX-523 MET DB06266|Lonidamine CFTR;HK1 common genes common pathways GO:0016310| phosphorylation HK1;MET 43314:[DB06314 DB00351] DB06314|SGX-523 MET DB00351|Megestrol acetate PGR;NR3C1;CYP3A4;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;NR3C1;MET GO:0007165| signal transduction NR3C1;PGR;MET 43315:[DB06314 DB04858] DB06314|SGX-523 MET DB04858|Tirapazamine CYP2E1 common genes common pathways 43316:[DB06314 DB11672] DB06314|SGX-523 MET DB11672|Curcumin PPARG;VDR;ABCC5;CBR1;GSTP1;CYP2C9;CYP3A4;CYP2B6;CYP1A2;CYP2D6;GSTA1;GSTM1;GSTP1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG;VDR GO:0007165| signal transduction MET;PPARG;VDR 43317:[DB06314 DB05457] DB06314|SGX-523 MET DB05457|OSI-7904L TYMS common genes common pathways 43318:[DB06314 DB02032] DB06314|SGX-523 MET DB02032|1-(3-Mercapto-2-Methyl-Propionyl)-Pyrrolidine-2-Carboxylic Acid ACE common genes common pathways 43319:[DB06314 DB00668] DB06314|SGX-523 MET DB00668|Epinephrine ADRA1A;ADRA1B;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA1D;TNF;CYP2C9;CYP3A4;COMT;MAOA;MAOB;SLC22A2;SLC22A1 common genes common pathways GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation ADRA1B;ADRA1D;MET GO:0007165| signal transduction ADRA2B;ADRA1A;ADRA1B;ADRB1;ADRB2;MET;ADRA2A;ADRA1D GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0000165| MAPKKK cascade TNF;MET GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET;TNF 43320:[DB06314 DB09295] DB06314|SGX-523 MET DB09295|Talniflumate PTGS1;PTGS2;CLCNKA;PTGS1;PTGS2 common genes common pathways 43321:[DB06314 DB00328] DB06314|SGX-523 MET DB00328|Indometacin PTGS1;PTGS2;PLA2G2A;PTGR2;PPARG;GLO1;PTGDR2;PPARA;AKR1C3;CYP2C19;CYP2C9;CES1;UGT1A9;UGT1A1;UGT2B7;ALB;ABCC3;ABCC4;ABCC6;ABCB1;ABCC1;SLCO1A2;SLC22A6;SLC22A8;ABCC2;ABCC11;SLC22A11;SLC10A1;SLC22A7;SLCO1B1;ABCB11 common genes common pathways GO:0007165| signal transduction PTGDR2;PPARG;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARA;PPARG GO:0051897| positive regulation of protein kinase B signaling cascade MET;AKR1C3 43322:[DB06314 DB00394] DB06314|SGX-523 MET DB00394|Beclomethasone dipropionate NR3C1;CYP3A5;CYP3A4;SERPINA6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 GO:0007165| signal transduction MET;NR3C1 43323:[DB06314 DB00286] DB06314|SGX-523 MET DB00286|Conjugated estrogens ESR1;CYP3A4;CYP1A2;COMT;ABCC3;ABCC4;ABCC1;SLCO1A2;SLC10A1;SLC22A10;SLC22A8;SLCO1C1;SLCO1B1;SLCO2B1;ABCB1;SLC22A6;SLC51A;SLC51B;ABCC2;SLCO4A1;ABCC11;SLCO1B3;SLC22A11;SLCO3A1;ABCG2 common genes common pathways GO:0007165| signal transduction ESR1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET 43324:[DB06314 DB00811] DB06314|SGX-523 MET DB00811|Ribavirin IMPDH1;IMPDH2;PB1;NT5C2;ENPP1;ADK;SLC28A3;SLC29A1 common genes common pathways GO:0016310| phosphorylation NT5C2;ADK;MET 43325:[DB06314 DB05395] DB06314|SGX-523 MET DB05395|Amibegron ADRB3 common genes common pathways GO:0007165| signal transduction MET;ADRB3 43326:[DB06314 DB00577] DB06314|SGX-523 MET DB00577|Valaciclovir SLC15A1;SLC15A2;SLC22A8;SLC22A6;SLC6A14;SLC10A2 common genes common pathways 43327:[DB06314 DB01397] DB06314|SGX-523 MET DB01397|Magnesium salicylate PTGS2;PTGS1;ALB common genes common pathways 43328:[DB06314 DB00532] DB06314|SGX-523 MET DB00532|Mephenytoin SCN5A;NR1I2;CYP2C19;CYP2B6;CYP1A2;CYP2D6;CYP2C8;CYP2C9 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET GO:0007165| signal transduction MET;NR1I2 43329:[DB06314 DB01017] DB06314|SGX-523 MET DB01017|Minocycline rpsI;rpsD;IL1B;ALOX5;MMP9;VEGFA;CASP1;CASP3;CYCS;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways GO:0048754| branching morphogenesis of a tube MET;VEGFA GO:0007165| signal transduction MET;CASP1;IL1B GO:0000165| MAPKKK cascade MET;IL1B GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;IL1B;MET GO:0050918| positive chemotaxis MET;VEGFA 43330:[DB06314 DB01149] DB06314|SGX-523 MET DB01149|Nefazodone HTR2A;HTR2C;SLC6A4;HTR1A;SLC6A2;SLC6A3;ADRA1B;ADRA2A;ADRA1A;KCNH2;CYP3A5;CYP3A4;CYP2B;CYP2D6;CYP3A4;CYP3A43;CYP3A5;CYP3A7;ABCB1;SLCO1B3;SLCO2B1;ABCB11 common genes common pathways GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1B;HTR1A;MET GO:0007165| signal transduction MET;HTR2C;ADRA2A;HTR1A;ADRA1B;HTR2A;ADRA1A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET 43331:[DB06314 DB05478] DB06314|SGX-523 MET DB05478|Pradefovir Mesylate CYP3A4 common genes common pathways 43332:[DB06314 DB00456] DB06314|SGX-523 MET DB00456|Cefalotin ALB;SLC22A5;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11;SLC22A7 common genes common pathways 43333:[DB06314 DB03214] DB06314|SGX-523 MET DB03214|Vinylglycine ACCS;IL4I1 common genes common pathways 43334:[DB06314 DB11582] DB06314|SGX-523 MET DB11582|Thiocolchicoside GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GLRA1;TNFSF11 common genes common pathways GO:0007165| signal transduction GABRA5;GABRD;GABRA6;GABRB1;GABRB3;MET;GABRP;GABRQ;GABRE GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNFSF11;MET GO:0051897| positive regulation of protein kinase B signaling cascade TNFSF11;MET 43335:[DB06314 DB06081] DB06314|SGX-523 MET DB06081|Caplacizumab VWF common genes common pathways 43336:[DB06314 DB12637] DB06314|SGX-523 MET DB12637|Onapristone NR3C1;ADGRD1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 GO:0007166| cell surface receptor linked signaling pathway MET;ADGRD1 GO:0007165| signal transduction NR3C1;ADGRD1;MET 43337:[DB06314 DB01190] DB06314|SGX-523 MET DB01190|Clindamycin rplJ;CYP3A4 common genes common pathways 43338:[DB06314 DB00982] DB06314|SGX-523 MET DB00982|Isotretinoin RARA common genes common pathways GO:0007165| signal transduction MET;RARA GO:0006468| protein phosphorylation MET;RARA GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;RARA 43339:[DB06314 DB01328] DB06314|SGX-523 MET DB01328|Cefonicid mrcA;ALB common genes common pathways 43340:[DB06314 DB04817] DB06314|SGX-523 MET DB04817|Metamizole PTGS1;CYP2B6;CYP3A4 common genes common pathways 43341:[DB06314 DB00202] DB06314|SGX-523 MET DB00202|Succinylcholine CHRNA10;CHRNA7;CHRM1;CHRM2;CHRM3;BCHE common genes common pathways GO:0008283| cell proliferation CHRM3;MET;CHRM1 GO:0007165| signal transduction MET;CHRM2;CHRM3;CHRM1;CHRNA10;CHRNA7 43342:[DB06314 DB13178] DB06314|SGX-523 MET DB13178|Inositol SLC5A3 common genes common pathways 43343:[DB06314 DB11692] DB06314|SGX-523 MET DB11692|Pavinetant TACR3 common genes common pathways GO:0007165| signal transduction TACR3;MET 43344:[DB06314 DB06735] DB06314|SGX-523 MET DB06735|Enclomiphene CYP2D6 common genes common pathways 43345:[DB06314 DB01364] DB06314|SGX-523 MET DB01364|Ephedrine SLC6A2;ADRA1A;SLC18A2;ACHE;BCHE common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1A;MET GO:0008283| cell proliferation ACHE;MET GO:0010507| negative regulation of autophagy MET;ADRA1A 43346:[DB06314 DB06697] DB06314|SGX-523 MET DB06697|Artemether CYP3A4;CYP3A5;CYP2B6;CYP2C9;CYP2C19;CYP2D6 common genes common pathways 43347:[DB06314 DB04381] DB06314|SGX-523 MET DB04381|Crotonaldehyde ALDH2 common genes common pathways 43348:[DB06314 DB01095] DB06314|SGX-523 MET DB01095|Fluvastatin HMGCR;CYP1A1;CYP3A4;CYP3A5;CYP2C8;CYP2C9;CYP2C19;CYP2D6;UGT1A1;UGT1A3;UGT2B7;CYP2B6;SLCO1B1;SLCO1B3;SLCO2B1;SLC15A1;ABCC2 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 43349:[DB06314 DB03991] DB06314|SGX-523 MET DB03991|2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid NEU2 common genes common pathways 43350:[DB06314 DB05200] DB06314|SGX-523 MET DB05200|AT2220 GAA common genes common pathways 43351:[DB06314 DB14063] DB06314|SGX-523 MET DB14063|Dexverapamil ABCB1;CYP3A4 common genes common pathways 43352:[DB06314 DB04953] DB06314|SGX-523 MET DB04953|Ezogabine KCNQ2;KCNQ3;KCNQ4;KCNQ5;UGT1A1;UGT1A3;UGT1A4;UGT1A9;NAT2 common genes common pathways 43353:[DB06314 DB06707] DB06314|SGX-523 MET DB06707|Levonordefrin ADRA2A;ADRA2B;ADRA2C common genes common pathways GO:0007165| signal transduction ADRA2B;MET;ADRA2C;ADRA2A 43354:[DB06314 DB09143] DB06314|SGX-523 MET DB09143|Sonidegib SMO;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;SMO GO:0007166| cell surface receptor linked signaling pathway SMO;MET GO:0007165| signal transduction SMO;MET 43355:[DB06314 DB00293] DB06314|SGX-523 MET DB00293|Raltitrexed TYMS;FPGS common genes common pathways GO:0008283| cell proliferation MET;FPGS 43356:[DB06314 DB00320] DB06314|SGX-523 MET DB00320|Dihydroergotamine HTR1D;HTR1B;ADRA2A;HTR2B;CYP3A4;ABCB1 common genes common pathways GO:0016310| phosphorylation MET;HTR2B GO:0007165| signal transduction HTR1D;HTR2B;MET;ADRA2A;HTR1B GO:0010507| negative regulation of autophagy HTR2B;MET 43357:[DB06314 DB00835] DB06314|SGX-523 MET DB00835|Brompheniramine HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;CYP2B6;CYP2C19;CYP2C8;CYP2E1;CYP3A4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0008283| cell proliferation CHRM3;MET;CHRM5;CHRM4;CHRM1 GO:0007165| signal transduction CHRM3;CHRM2;MET;CHRM5;HRH1;CHRM4;CHRM1 43358:[DB06314 DB00576] DB06314|SGX-523 MET DB00576|Sulfamethizole CYP2C9;ALB common genes common pathways 43359:[DB06314 DB01213] DB06314|SGX-523 MET DB01213|Fomepizole ADH1A;ADH1B;ADH1C;CAT;CYP2E1;CYP2A6 common genes common pathways 43360:[DB06314 DB00718] DB06314|SGX-523 MET DB00718|Adefovir Dipivoxil AK2;AK4;NME1;NME2;SLC22A6;ABCC4;ABCC5;SLC22A3 common genes common pathways GO:0016310| phosphorylation NME2;MET;NME1;AK2;AK4 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NME2;MET 43361:[DB06314 DB00368] DB06314|SGX-523 MET DB00368|Norepinephrine ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3;PAH;SLC18A2;SLC18A1;SLC6A2;SLC22A2;SLC22A3;SLC22A5;SLC22A1;POU5F1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2;POU5F1 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction ADRA2A;MET;ADRB2;ADRA2C;ADRA1D;ADRA1A;ADRB3;ADRA2B;ADRB1;ADRA1B GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation MET;ADRA1D;ADRA1B 43362:[DB06314 DB00151] DB06314|SGX-523 MET DB00151|L-Cysteine GCLM;GCLC;GOT1;CTH;CBS;CARS;MGMT;GSS;SLC19A3;CARS2;CSAD;NFS1;CDO1;SLC16A10 common genes common pathways 43363:[DB06314 DB02751] DB06314|SGX-523 MET DB02751|Glycocyamine GAMT common genes common pathways 43364:[DB06314 DB03185] DB06314|SGX-523 MET DB03185|1-Beta-Ribofuranosyl-1,3-Diazepinone CDA;CDA common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CDA;MET 43365:[DB06314 DB09038] DB06314|SGX-523 MET DB09038|Empagliflozin SLC5A2 common genes common pathways 43366:[DB06314 DB00074] DB06314|SGX-523 MET DB00074|Basiliximab IL2RA;IL2RB;FCGR1A;FCGR3A;FCGR2A;FCGR2B;FCGR2C;FCGR3B;C1S;C1R;C1QA;C1QB;C1QC common genes common pathways GO:0007166| cell surface receptor linked signaling pathway IL2RA;MET GO:0000165| MAPKKK cascade MET;IL2RA;IL2RB GO:0007165| signal transduction FCGR2C;FCGR2B;IL2RB;MET;FCGR1A GO:0008283| cell proliferation MET;IL2RA 43367:[DB06314 DB00755] DB06314|SGX-523 MET DB00755|Tretinoin RXRB;RXRG;RARG;ALDH1A1;GPRC5A;NR0B1;ALDH1A2;RARRES1;RARA;RARB;LCN1;OBP2A;RBP4;PDK4;RXRA;CYP26A1;CYP26B1;CYP26C1;HPGDS;CYP3A7;CYP2B6;CYP2C8;CYP2C9;CYP3A4;CYP3A5;CYP2A6;CYP2C18;CYP1A1;CYP4A11;ALB;CRABP1;CRABP2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;RARB;MET;RXRB;RARA;RARG;RXRG GO:0006468| protein phosphorylation MET;PDK4;RARA GO:0016310| phosphorylation PDK4;MET GO:0007165| signal transduction CRABP2;RARA;MET;CRABP1;GPRC5A;RARB;HPGDS GO:0008283| cell proliferation MET;CYP1A1 GO:0061436| CYP26B1;MET 43368:[DB06314 DB00749] DB06314|SGX-523 MET DB00749|Etodolac PTGS2;PTGS1;RXRA;CYP2C9;UGT1A9;UGT1A3;UGT1A10;UGT2B7;ALB;SLC22A6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter RXRA;MET 43369:[DB06314 DB03128] DB06314|SGX-523 MET DB03128|Acetylcholine ACHE;CHRM1;CHRM2;CHRM3;CHRM4;CHRNA7;SLC22A5;SLC22A1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0008283| cell proliferation CHRM4;CHRM1;CHRM3;MET;ACHE GO:0007165| signal transduction CHRM4;CHRM1;CHRM3;CHRM2;MET;CHRNA7 43370:[DB06314 DB01306] DB06314|SGX-523 MET DB01306|Insulin Aspart INSR common genes common pathways GO:0006468| protein phosphorylation MET;INSR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;INSR GO:0016310| phosphorylation MET;INSR GO:0018108| peptidyl-tyrosine phosphorylation MET;INSR GO:0051897| positive regulation of protein kinase B signaling cascade INSR;MET 43371:[DB06314 DB14570] DB06314|SGX-523 MET DB14570|Hydroxyprogesterone CYP3A4 common genes common pathways 43372:[DB06314 DB05773] DB06314|SGX-523 MET DB05773|Trastuzumab emtansine ERBB2;CYP3A4;CYP3A5;ABCB1 common genes common pathways GO:0000165| MAPKKK cascade ERBB2;MET GO:0018108| peptidyl-tyrosine phosphorylation ERBB2;MET GO:0007166| cell surface receptor linked signaling pathway MET;ERBB2 GO:0008283| cell proliferation MET;ERBB2 GO:0007165| signal transduction ERBB2;MET GO:0006468| protein phosphorylation ERBB2;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;ERBB2 GO:0016310| phosphorylation ERBB2;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;ERBB2 GO:0046854| phosphatidylinositol phosphorylation ERBB2;MET 43373:[DB06314 DB00148] DB06314|SGX-523 MET DB00148|Creatine CKM;CKMT1A;CKB;CKMT2;SLC6A8;GAMT;SLC22A5 common genes common pathways GO:0016310| phosphorylation MET;CKM;CKB;CKMT1A;CKMT2 43374:[DB06314 DB06090] DB06314|SGX-523 MET DB06090|Bradanicline CHRNA7 common genes common pathways GO:0007165| signal transduction CHRNA7;MET 43375:[DB06314 DB01614] DB06314|SGX-523 MET DB01614|Acepromazine DRD2;DRD1;HTR2A;HTR1A;ADRA1A;ADRA1B;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation HTR1A;ADRA1B;MET GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction HTR2A;DRD1;ADRA1A;DRD2;HTR1A;ADRA1B;MET 43376:[DB06314 DB13151] DB06314|SGX-523 MET DB13151|Anti-inhibitor coagulant complex F10;F2;FGA;FGB;F13A1;F5;F8;F7;F2;F7;F8;F9;F5 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;F7;F10 GO:0007165| signal transduction FGA;FGB;MET GO:0007166| cell surface receptor linked signaling pathway MET;F2 43377:[DB06314 DB00475] DB06314|SGX-523 MET DB00475|Chlordiazepoxide GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRB1;GABRA6;GABRD;GABRA5;GABRQ;GABRE;GABRP;GABRB3;MET 43378:[DB06314 DB01431] DB06314|SGX-523 MET DB01431|Allylestrenol PGR;ESR1;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET;PGR GO:0007165| signal transduction MET;ESR1;PGR 43379:[DB06314 DB01610] DB06314|SGX-523 MET DB01610|Valganciclovir SLC15A1;SLC15A2;SLC6A14 common genes common pathways 43380:[DB06314 DB01382] DB06314|SGX-523 MET DB01382|Glycodiazine KCNJ1;ABCC8 common genes common pathways GO:0007165| signal transduction MET;ABCC8 43381:[DB06314 DB08836] DB06314|SGX-523 MET DB08836|Temocapril ACE;SLC15A1;SLCO1A2 common genes common pathways 43382:[DB06314 DB00165] DB06314|SGX-523 MET DB00165|Pyridoxine PDXK;CYP1A1 common genes common pathways GO:0016310| phosphorylation PDXK;MET GO:0008283| cell proliferation MET;CYP1A1;PDXK 43383:[DB06314 DB00714] DB06314|SGX-523 MET DB00714|Apomorphine DRD3;DRD4;DRD2;ADRA2C;ADRA2B;HTR2C;DRD5;HTR1A;HTR2A;HTR2B;ADRA2A;DRD1;HTR1D;HTR1B;CALY common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET GO:0016310| phosphorylation MET;HTR2B GO:0007165| signal transduction ADRA2A;HTR2C;MET;ADRA2C;HTR1B;DRD3;DRD5;DRD2;DRD1;HTR2A;ADRA2B;DRD4;HTR2B;HTR1D;HTR1A GO:0008283| cell proliferation HTR1A;MET GO:0010507| negative regulation of autophagy HTR2B;MET 43384:[DB06314 DB01600] DB06314|SGX-523 MET DB01600|Tiaprofenic acid PTGS2;PTGS1 common genes common pathways 43385:[DB06314 DB09099] DB06314|SGX-523 MET DB09099|Somatostatin SSTR1;SSTR2;SSTR3;SSTR4;SSTR5;CYP3A4;ABCB1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;SSTR1 GO:0007165| signal transduction SSTR2;SSTR1;MET;SSTR5;SSTR3;SSTR4 43386:[DB06314 DB06699] DB06314|SGX-523 MET DB06699|Degarelix GNRHR common genes common pathways GO:0007165| signal transduction GNRHR;MET 43387:[DB06314 DB00176] DB06314|SGX-523 MET DB00176|Fluvoxamine SLC6A4;KCNH2;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP3A4;CYP3A5;CYP3A7;CYP2C9;CYP2C19;CYP2B6;CYP2C8;ABCB1;ABCB11 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 43388:[DB06314 DB05687] DB06314|SGX-523 MET DB05687|BL-1020 DRD2;HTR2A common genes common pathways GO:0007165| signal transduction HTR2A;DRD2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET 43389:[DB06314 DB06822] DB06314|SGX-523 MET DB06822|Tinzaparin SERPINC1;ITGA4;CXCL12;ADAMTS4 common genes common pathways GO:0050918| positive chemotaxis MET;CXCL12 GO:0007165| signal transduction CXCL12;MET 43390:[DB06314 DB00200] DB06314|SGX-523 MET DB00200|Hydroxocobalamin MTR;MUT;MTRR;MMAA;TCN1;AMN;CUBN;MMAB;MMACHC;TCN2 common genes common pathways 43391:[DB06314 DB09564] DB06314|SGX-523 MET DB09564|Insulin Degludec INSR common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade INSR;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;INSR GO:0016310| phosphorylation INSR;MET GO:0006468| protein phosphorylation INSR;MET GO:0018108| peptidyl-tyrosine phosphorylation INSR;MET 43392:[DB06314 DB14517] DB06314|SGX-523 MET DB14517|Aluminium phosphate TF;ATP1A1;KLK1;APP;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;APP GO:0051897| positive regulation of protein kinase B signaling cascade MET;APP GO:0050918| positive chemotaxis APP;MET GO:0006468| protein phosphorylation MET;APP 43393:[DB06314 DB01212] DB06314|SGX-523 MET DB01212|Ceftriaxone SLC22A11;SLC22A6;SLC22A8;SLC15A1;GLUL;ALB;SLC15A1;SLC15A2;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0008283| cell proliferation MET;GLUL 43394:[DB06314 DB11921] DB06314|SGX-523 MET DB11921|Deflazacort CYP3A4 common genes common pathways 43395:[DB06314 DB01289] DB06314|SGX-523 MET DB01289|Glisoxepide KCNJ8;CYP2C9 common genes common pathways 43396:[DB06314 DB00762] DB06314|SGX-523 MET DB00762|Irinotecan TOP1;TOP1MT;CYP3A4;CYP3A5;CYP2B6;CYP3A7;UGT1A1;UGT1A9;CES1;CES2;BCHE;ALB;SLC22A3;SLCO1B1;ABCC1;ABCG2;ABCB1;ABCC2 common genes common pathways GO:0016310| phosphorylation TOP1;MET 43397:[DB06314 DB00357] DB06314|SGX-523 MET DB00357|Aminoglutethimide CYP19A1;CYP11A1;CYP3A4;CYP2C19 common genes common pathways 43398:[DB06314 DB00243] DB06314|SGX-523 MET DB00243|Ranolazine SCN5A;SCN9A;CYP3A4;CYP2D6;ABCB11 common genes common pathways 43399:[DB06314 DB06191] DB06314|SGX-523 MET DB06191|Zosuquidar ABCB1;SLCO1B1 common genes common pathways 43400:[DB06314 DB00884] DB06314|SGX-523 MET DB00884|Risedronate FDPS;PTGS2 common genes common pathways 43401:[DB06314 DB01014] DB06314|SGX-523 MET DB01014|Balsalazide PPARG;PTGS2;PTGS1;ALOX5 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG GO:0007165| signal transduction PPARG;MET 43402:[DB06314 DB04334] DB06314|SGX-523 MET DB04334|6-hydroxydopa quinone AOC3 common genes common pathways 43403:[DB06314 DB09309] DB06314|SGX-523 MET DB09309|Kitasamycin CYP3A4 common genes common pathways 43404:[DB06314 DB00993] DB06314|SGX-523 MET DB00993|Azathioprine HPRT1;RAC1;XDH;TPMT;GSTA1;GSTA2;GSTM1;CYP1A2 common genes common pathways GO:0048012| hepatocyte growth factor receptor signaling pathway MET;RAC1 GO:0071526| semaphorin-plexin signaling pathway RAC1;MET GO:0031116| positive regulation of microtubule polymerization RAC1;MET GO:0008283| cell proliferation MET;RAC1 GO:0006468| protein phosphorylation RAC1;MET 43405:[DB06314 DB01056] DB06314|SGX-523 MET DB01056|Tocainide SCN5A;CYP1A2;ALB common genes common pathways 43406:[DB06314 DB00555] DB06314|SGX-523 MET DB00555|Lamotrigine CACNA1E;SCN2A;ADORA1;ADORA2A;ADRA1A;ADRA2A;ADRB1;DRD1;DRD5;DRD2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRG1;GABRG2;GABRG3;HRH1;OPRK1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR3A;UGT1A4;DHFR;UGT1A3;UGT1A1;ABCB1;SLC22A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction CHRM4;OPRK1;GABRP;DRD5;GABRQ;GABRE;CHRM1;ADRA2A;CHRM3;ADORA1;GABRB3;HRH1;MET;CHRM5;CHRM2;ADRB1;ADORA2A;GABRD;GABRB1;GABRA6;HTR3A;ADRA1A;DRD2;GABRA5;DRD1;HTR2A GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation MET;CHRM5;CHRM3;CHRM1;CHRM4 GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET 43407:[DB06314 DB11077] DB06314|SGX-523 MET DB11077|Polyethylene glycol 400 ENPP1;CYP4A11;ADH5;SULT1A1 common genes common pathways 43408:[DB06314 DB11487] DB06314|SGX-523 MET DB11487|Dexamethasone isonicotinate CYP3A4 common genes common pathways 43409:[DB06314 DB04896] DB06314|SGX-523 MET DB04896|Milnacipran SLC6A4;SLC6A2;GRIN1;GRIN2A;GRIN2B;GRIN2C;GRIN2D;GRIN3A;GRIN3B;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;GRIN1 GO:0000165| MAPKKK cascade GRIN2C;GRIN1;GRIN2B;GRIN2A;GRIN2D;MET 43410:[DB06314 DB01354] DB06314|SGX-523 MET DB01354|Heptabarbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2 common genes common pathways GO:0007165| signal transduction GABRA5;CHRNA7;CHRNA4;GABRA6;GRIA2;MET 43411:[DB06314 DB01255] DB06314|SGX-523 MET DB01255|Lisdexamfetamine TAAR1;CYP2D6;SLC15A1 common genes common pathways GO:0007165| signal transduction TAAR1;MET 43412:[DB06314 DB01253] DB06314|SGX-523 MET DB01253|Ergometrine ADRA1A;CYP3A4;ABCB1 common genes common pathways GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0007165| signal transduction ADRA1A;MET GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET 43413:[DB06314 DB01202] DB06314|SGX-523 MET DB01202|Levetiracetam SV2A;CACNA1B;CYP3A4;ABCB1;ABCC2 common genes common pathways 43414:[DB06314 DB04263] DB06314|SGX-523 MET DB04263|Geneticin ODC1 common genes common pathways 43415:[DB06314 DB00344] DB06314|SGX-523 MET DB00344|Protriptyline SLC6A2;SLC6A4;CYP2D6;ABCB1 common genes common pathways 43416:[DB06314 DB00007] DB06314|SGX-523 MET DB00007|Leuprolide GNRHR;CYP3A4 common genes common pathways GO:0007165| signal transduction GNRHR;MET 43417:[DB06314 DB06420] DB06314|SGX-523 MET DB06420|Annamycin TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43418:[DB06314 DB09238] DB06314|SGX-523 MET DB09238|Manidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CACNA1G;CACNA1H;CACNA1I;CYP2C9;CYP2D6;CYP1A1;CYP2B6;CYP2C19;CYP3A4 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 GO:0007165| signal transduction CACNA1I;MET 43419:[DB06314 DB00301] DB06314|SGX-523 MET DB00301|Flucloxacillin CYP3A4;ABCB11 common genes common pathways 43420:[DB06314 DB00547] DB06314|SGX-523 MET DB00547|Desoximetasone NR3C1 common genes common pathways GO:0007165| signal transduction MET;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 43421:[DB06314 DB04835] DB06314|SGX-523 MET DB04835|Maraviroc CCR5;CYP3A4 common genes common pathways GO:0007165| signal transduction CCR5;MET GO:0000165| MAPKKK cascade CCR5;MET GO:0007166| cell surface receptor linked signaling pathway CCR5;MET 43422:[DB06314 DB00868] DB06314|SGX-523 MET DB00868|Benzonatate SCN5A common genes common pathways 43423:[DB06314 DB00255] DB06314|SGX-523 MET DB00255|Diethylstilbestrol ESR1;ESRRG;ESR2;ESRRA;ESRRB;NCOA2;NR1I2;AR;SHBG;COMT;CYP19A1;CYP3A4;CYP2C8;CYP2C9;CYP2E1;TTR;ABCG2;ABCB1;SLCO1B1;SLCO2B1;ABCB11 common genes common pathways GO:0008283| cell proliferation MET;AR;ESRRB GO:0007165| signal transduction AR;MET;NR1I2;ESR1;ESR2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;ESRRA;NCOA2;ESRRB;ESRRG;MET;NR1I2;ESR1;ESR2 43424:[DB06314 DB09103] DB06314|SGX-523 MET DB09103|Ancestim KIT common genes common pathways GO:0007165| signal transduction MET;KIT GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway KIT;MET GO:0016310| phosphorylation KIT;MET GO:0006468| protein phosphorylation KIT;MET GO:0000165| MAPKKK cascade MET;KIT GO:0018108| peptidyl-tyrosine phosphorylation KIT;MET GO:0046854| phosphatidylinositol phosphorylation KIT;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;KIT 43425:[DB06314 DB00455] DB06314|SGX-523 MET DB00455|Loratadine HRH1;KCNH2;CYP2C8;CYP3A4;CYP2C19;CYP2D6;ABCB1;ABCB11 common genes common pathways GO:0007165| signal transduction HRH1;MET 43426:[DB06314 DB05077] DB06314|SGX-523 MET DB05077|SLV319 CNR1 common genes common pathways GO:0007165| signal transduction MET;CNR1 43427:[DB06314 DB04573] DB06314|SGX-523 MET DB04573|Estriol ESR1;ESR2;SHBG;SLCO1A2;ABCB1 common genes common pathways GO:0007165| signal transduction MET;ESR2;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;ESR2;MET 43428:[DB06314 DB06963] DB06314|SGX-523 MET DB06963|3-[3-(3-methyl-6-{[(1S)-1-phenylethyl]amino}-1H-pyrazolo[4,3-c]pyridin-1-yl)phenyl]propanamide PLK1 common genes common pathways GO:0008283| cell proliferation MET;PLK1 GO:0016310| phosphorylation MET;PLK1 GO:0006468| protein phosphorylation PLK1;MET 43429:[DB06314 DB00893] DB06314|SGX-523 MET DB00893|Iron Dextran HBB;HBA1;FTH1;FTL;TF common genes common pathways 43430:[DB06314 DB13874] DB06314|SGX-523 MET DB13874|Enasidenib IDH2;CYP1A2;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;UGT1A1;UGT1A3;UGT1A4;UGT1A9;UGT2B7;UGT2B15;ABCB1;ABCG2;SLC22A6;SLCO1B1;SLC22A2;SLCO1B3;SLC22A8 common genes common pathways 43431:[DB06314 DB06802] DB06314|SGX-523 MET DB06802|Nepafenac PTGS1;PTGS2 common genes common pathways 43432:[DB06314 DB01764] DB06314|SGX-523 MET DB01764|Dalfopristin vatD;CYP3A4 common genes common pathways 43433:[DB06314 DB06144] DB06314|SGX-523 MET DB06144|Sertindole DRD2;HTR2A;HTR2C;HTR6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP2D6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction HTR2A;DRD2;ADRA1A;ADRA1B;MET;HTR2C;HTR6;ADRA1D GO:0008283| cell proliferation MET;ADRA1D;ADRA1B GO:0010507| negative regulation of autophagy ADRA1A;MET 43434:[DB06314 DB00797] DB06314|SGX-523 MET DB00797|Tolazoline ADRA1A;ADRA2A;HRH1;HRH2;ADRA2C;ADRA2B common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1A;HRH2;ADRA2B;ADRA2A;ADRA2C;HRH1;MET GO:0010507| negative regulation of autophagy ADRA1A;MET 43435:[DB06314 DB00345] DB06314|SGX-523 MET DB00345|Aminohippuric acid SLC22A2;SLC22A5;SLC22A6;SLC22A8;ABCC2;SLC22A4;SLC22A11;SLCO3A1;SLCO1B1;ABCC1;SLCO1A2;SLC16A1;SLC22A7 common genes common pathways 43436:[DB06314 DB02783] DB06314|SGX-523 MET DB02783|4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate GOT2 common genes common pathways 43437:[DB06314 DB06444] DB06314|SGX-523 MET DB06444|Dexanabinol TNF common genes common pathways GO:0000165| MAPKKK cascade TNF;MET GO:0051897| positive regulation of protein kinase B signaling cascade MET;TNF GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TNF 43438:[DB06314 DB14072] DB06314|SGX-523 MET DB14072|Reversin 121 ABCB1 common genes common pathways 43439:[DB06314 DB05758] DB06314|SGX-523 MET DB05758|CYT007-TNFQb TNF common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;MET GO:0051897| positive regulation of protein kinase B signaling cascade TNF;MET GO:0000165| MAPKKK cascade MET;TNF 43440:[DB06314 DB01136] DB06314|SGX-523 MET DB01136|Carvedilol ADRB1;ADRA1A;NDUFC2;ADRB2;VEGFA;NPPB;GJA1;KCNH2;VCAM1;ADRA1D;ADRA1B;ADRA2C;ADRA2B;ADRA2A;SELE;HIF1A;KCNJ4;XDH;CYP2C9;CYP2D6;CYP1A2;CYP3A4;CYP1A1;CYP2E1;PTGS1;UGT1A1;ABCB1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET;NPPB GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0048754| branching morphogenesis of a tube VEGFA;MET GO:0007165| signal transduction GJA1;ADRA1B;HIF1A;ADRB1;ADRA2B;ADRA1A;ADRA1D;ADRA2C;ADRB2;MET;ADRA2A GO:0008283| cell proliferation ADRA1B;CYP1A1;ADRA1D;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter VEGFA;HIF1A;ADRB2;MET GO:0050918| positive chemotaxis VEGFA;MET 43441:[DB06314 DB00717] DB06314|SGX-523 MET DB00717|Norethisterone PGR;CYP3A4;CYP3A5;CYP3A7;CYP2C19;ALB;SHBG;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PGR GO:0007165| signal transduction PGR;MET 43442:[DB06314 DB06495] DB06314|SGX-523 MET DB06495|Onercept TNF common genes common pathways GO:0000165| MAPKKK cascade TNF;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;MET GO:0051897| positive regulation of protein kinase B signaling cascade TNF;MET 43443:[DB06314 DB01621] DB06314|SGX-523 MET DB01621|Pipotiazine DRD2;DRD1;HTR2A;HTR1A;CYP3A4;CYP2D6;CYP2C19;ALB;SLC22A1 common genes common pathways GO:0008283| cell proliferation HTR1A;MET GO:0007165| signal transduction MET;HTR1A;DRD1;HTR2A;DRD2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 43444:[DB06314 DB11471] DB06314|SGX-523 MET DB11471|Tilmicosin CYP3A4 common genes common pathways 43445:[DB06314 DB04844] DB06314|SGX-523 MET DB04844|Tetrabenazine SLC18A2;DRD2;CYP2D6;CBR1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0007165| signal transduction DRD2;MET 43446:[DB06314 DB00425] DB06314|SGX-523 MET DB00425|Zolpidem GABRA1;GABRA2;GABRA3;GABRB3;GABRG2;CYP3A5;CYP3A7;CYP3A4;CYP1A2;CYP2C9;CYP2C19;CYP2D6;PTGS1 common genes common pathways GO:0007165| signal transduction MET;GABRB3 43447:[DB06314 DB11278] DB06314|SGX-523 MET DB11278|DL-Methylephedrine ADRB1;ADRA2A;ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;ADRB1;ADRB2;ADRB3 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRB1;ADRA1B;ADRB3;ADRA1A;ADRA2B;ADRA1D;ADRA2A;ADRA2C;ADRB2;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 43448:[DB06314 DB14502] DB06314|SGX-523 MET DB14502|Sodium phosphate, dibasic SLC20A1;SLC20A2;SLC34A1;SLC34A2;SLC34A3 common genes common pathways GO:0007165| signal transduction MET;SLC20A1 43449:[DB06314 DB09036] DB06314|SGX-523 MET DB09036|Siltuximab IL6;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL6;MET 43450:[DB06314 DB03542] DB06314|SGX-523 MET DB03542|L-Myo-Inositol-1-Phosphate IMPA1 common genes common pathways GO:0007165| signal transduction IMPA1;MET GO:0046854| phosphatidylinositol phosphorylation MET;IMPA1 43451:[DB06314 DB11979] DB06314|SGX-523 MET DB11979|Elagolix GNRHR;CYP3A4;CYP3A43;CYP3A5;CYP3A7;CYP2D6;CYP2C8;ABCB1;SLCO1B1 common genes common pathways GO:0007165| signal transduction MET;GNRHR 43452:[DB06314 DB06510] DB06314|SGX-523 MET DB06510|Muraglitazar PPARA;PPARG;CYP1A2;UGT1A3;UGT1A1;CYP2C8 common genes common pathways GO:0007165| signal transduction PPARG;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG;PPARA 43453:[DB06314 DB07776] DB06314|SGX-523 MET DB07776|Flavone ESRRA;ESRRB;CYP1B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESRRB;ESRRA;MET GO:0008283| cell proliferation MET;ESRRB 43454:[DB06314 DB00922] DB06314|SGX-523 MET DB00922|Levosimendan TNNC1;KCNJ11;KCNJ8;PDE3A common genes common pathways GO:0007165| signal transduction MET;PDE3A 43455:[DB06314 DB01176] DB06314|SGX-523 MET DB01176|Cyclizine HRH1;SULT1E1;CYP2C9 common genes common pathways GO:0007165| signal transduction HRH1;MET 43456:[DB06314 DB00962] DB06314|SGX-523 MET DB00962|Zaleplon GABRA1;TSPO;CYP3A4;CYP3A5;CYP3A7;AOX1 common genes common pathways GO:0008283| cell proliferation MET;TSPO GO:0007165| signal transduction TSPO;MET 43457:[DB06314 DB09328] DB06314|SGX-523 MET DB09328|Vayarin CYP2E1;CYP1A2;FADS1;ELOVL4;ACAT1;ACAA1 common genes common pathways 43458:[DB06314 DB01026] DB06314|SGX-523 MET DB01026|Ketoconazole AR;CYP21A2;CYP19A1;KCNH2;NR1I2;NR1I3;CYP1A1;CYP1A2;CYP1B1;CYP2A6;CYP2B6;CYP2C8;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11A1;CYP26A1;CYP51A1;UGT1A1;UGT2B7;CYP4F12;CYP4F2;ABCB11;ABCB1;SLCO1A2;SLCO1B1 common genes common pathways GO:0007165| signal transduction NR1I2;MET;NR1I3;AR GO:0008283| cell proliferation AR;CYP1A1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2;NR1I3;AR 43459:[DB06314 DB00784] DB06314|SGX-523 MET DB00784|Mefenamic acid PTGS2;PTGS1;CYP2C9;CYP2C8;UGT1A9;ALB common genes common pathways 43460:[DB06314 DB11155] DB06314|SGX-523 MET DB11155|Triclocarban fabI;CYP1A1;CYP1B1 common genes common pathways GO:0008283| cell proliferation MET;CYP1A1 43461:[DB06314 DB11751] DB06314|SGX-523 MET DB11751|Cabotegravir SLC22A6;SLC22A8 common genes common pathways 43462:[DB06314 DB01203] DB06314|SGX-523 MET DB01203|Nadolol ADRB1;ADRB2;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007165| signal transduction ADRB2;MET;ADRB1 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 43463:[DB06314 DB04911] DB06314|SGX-523 MET DB04911|Oritavancin CYP3A4;CYP2D6;CYP2C9;CYP2C19 common genes common pathways 43464:[DB06314 DB01048] DB06314|SGX-523 MET DB01048|Abacavir pol;HLA-B;ADH6;UGT1A1;ADK common genes common pathways GO:0016310| phosphorylation MET;ADK 43465:[DB06314 DB06228] DB06314|SGX-523 MET DB06228|Rivaroxaban F10;CYP3A4;CYP2J2;CYP3A5;ABCB1;ABCG2 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;F10 43466:[DB06314 DB11090] DB06314|SGX-523 MET DB11090|Potassium nitrate KCNH2;MUC1 common genes common pathways 43467:[DB06314 DB01097] DB06314|SGX-523 MET DB01097|Leflunomide DHODH;AHR;PTK2B;CYP2C9;CYP1A2;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;MET GO:0000165| MAPKKK cascade PTK2B;MET GO:0007166| cell surface receptor linked signaling pathway PTK2B;MET GO:0018108| peptidyl-tyrosine phosphorylation MET;PTK2B GO:0006468| protein phosphorylation PTK2B;MET GO:0016310| phosphorylation MET;PTK2B GO:0007165| signal transduction PTK2B;MET 43468:[DB06314 DB00670] DB06314|SGX-523 MET DB00670|Pirenzepine CHRM1 common genes common pathways GO:0008283| cell proliferation CHRM1;MET GO:0007165| signal transduction MET;CHRM1 43469:[DB06314 DB01169] DB06314|SGX-523 MET DB01169|Arsenic trioxide IKBKB;TXNRD1;JUN;CCND1;MAPK3;MAPK1;AKT1;CDKN1A;HDAC1;PML;CYP1A1;CYP1B1;CYP3A4;ALB;ABCC2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter AKT1;IKBKB;JUN;HDAC1;PML;MAPK3;MET GO:0000165| MAPKKK cascade MET;MAPK3;MAPK1 GO:0016310| phosphorylation IKBKB;AKT1;MAPK3;MET;MAPK1 GO:0006468| protein phosphorylation MET;MAPK3;MAPK1;CCND1;IKBKB;AKT1 GO:0007165| signal transduction MAPK1;MET;TXNRD1;AKT1 GO:0008283| cell proliferation TXNRD1;MET;CYP1A1;AKT1 GO:0010507| negative regulation of autophagy MET;AKT1 43470:[DB06314 DB04878] DB06314|SGX-523 MET DB04878|Voglibose MGAM common genes common pathways 43471:[DB06314 DB00113] DB06314|SGX-523 MET DB00113|Technetium Tc-99m arcitumomab CEACAM1 common genes common pathways 43472:[DB06314 DB00831] DB06314|SGX-523 MET DB00831|Trifluoperazine DRD2;CALY;ADRA1A;CALM1;TNNC1;S100A4;XDH;UGT1A4;CYP1A2;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0007165| signal transduction DRD2;ADRA1A;MET GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0000165| MAPKKK cascade MET;CALM1 43473:[DB06314 DB00311] DB06314|SGX-523 MET DB00311|Ethoxzolamide CA1;CA2;CA4;CA7;CA3;SLC22A6 common genes common pathways 43474:[DB06314 DB00308] DB06314|SGX-523 MET DB00308|Ibutilide CACNA1C;CACNB1;KCNH2;CACNA2D1;CACNG1;KCNK1;KCNK6;KCNH6;KCNH7;KCNJ11 common genes common pathways 43475:[DB06314 DB09225] DB06314|SGX-523 MET DB09225|Zotepine DRD1;DRD5;DRD2;HTR2A;HTR6;HTR7;SLC6A2;SLC6A4;CYP1A2;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0007165| signal transduction MET;HTR6;DRD5;HTR7;DRD1;HTR2A;DRD2 43476:[DB06314 DB09237] DB06314|SGX-523 MET DB09237|Levamlodipine CACNA1C;NOS3;NOS2;CYP3A4;NOS2;NOS3 common genes common pathways 43477:[DB06314 DB06762] DB06314|SGX-523 MET DB06762|Pinacidil CYP3A4 common genes common pathways 43478:[DB06314 DB00570] DB06314|SGX-523 MET DB00570|Vinblastine TUBA1A;TUBB;TUBD1;TUBG1;TUBE1;JUN;CYP3A4;CYP2D6;ABCB1;ABCC1;ABCC2;ABCC6;ABCB11;SLCO1B1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;JUN 43479:[DB06314 DB04348] DB06314|SGX-523 MET DB04348|Taurocholic Acid CEL;FABP6;NR1H4;ABCB11;ABCC1;SLCO1A2;SLC10A2;ABCC2;SLCO1B1;ABCC3;ABCC4;ABCB1;SLC22A6;ABCC10;SLC22A8;SLCO4A1;ABCC11;SLCO1C1;SLCO3A1;ABCG2;SLCO2B1;SLC16A1;SLC10A1;SLC51A;SLC51B;SLCO1B3;SLC7A11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1H4 GO:0007165| signal transduction NR1H4;MET 43480:[DB06314 DB00463] DB06314|SGX-523 MET DB00463|Metharbital GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRA5;GABRD;GABRB1;GABRA6;CHRNA4;CHRNA7;MET;GRIA2;GABRB3;GABRP;GABRE;GABRQ 43481:[DB06314 DB00680] DB06314|SGX-523 MET DB00680|Moricizine SCN5A common genes common pathways 43482:[DB06314 DB00579] DB06314|SGX-523 MET DB00579|Mazindol SLC6A2;SLC6A3;SLC6A4;SLC18A2 common genes common pathways 43483:[DB06314 DB04895] DB06314|SGX-523 MET DB04895|Pegaptanib NRP1 common genes common pathways GO:0007165| signal transduction NRP1;MET GO:0048012| hepatocyte growth factor receptor signaling pathway NRP1;MET GO:0071526| semaphorin-plexin signaling pathway NRP1;MET GO:0050918| positive chemotaxis MET;NRP1 43484:[DB06314 DB00678] DB06314|SGX-523 MET DB00678|Losartan AGTR1;CYP2C9;CYP3A4;CYP2C8;CYP2C19;UGT1A1;UGT1A3;UGT1A10;UGT2B7;UGT2B17;ALB;ABCB1;SLC22A6;SLC22A12;SLC2A9;ABCB11 common genes common pathways GO:0007165| signal transduction AGTR1;MET 43485:[DB06314 DB06695] DB06314|SGX-523 MET DB06695|Dabigatran etexilate F2;CES1;CES2;UGT1A9;UGT2B7;UGT2B15;NQO2;ABCB1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway F2;MET 43486:[DB06314 DB14538] DB06314|SGX-523 MET DB14538|Hydrocortisone aceponate ANXA1;NR3C1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;SLCO1A2;ABCG2;SLC22A8 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 GO:0007165| signal transduction NR3C1;ANXA1;MET GO:0007166| cell surface receptor linked signaling pathway ANXA1;MET 43487:[DB06314 DB06283] DB06314|SGX-523 MET DB06283|Ziconotide CYP3A4 common genes common pathways 43488:[DB06314 DB08819] DB06314|SGX-523 MET DB08819|Tafluprost PTGFR;PTGS2 common genes common pathways GO:0007165| signal transduction PTGFR;MET 43489:[DB06314 DB01384] DB06314|SGX-523 MET DB01384|Paramethasone NR3C1;CYP3A4;SERPINA6 common genes common pathways GO:0007165| signal transduction MET;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 43490:[DB06314 DB06712] DB06314|SGX-523 MET DB06712|Nilvadipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CACNA2D3;CYP3A4;CYP2A6;CYP2C19;CYP2C8;CYP2E1 common genes common pathways 43491:[DB06314 DB00627] DB06314|SGX-523 MET DB00627|Niacin HCAR3;HCAR2;QPRT;NNMT;CYP2D6;SLC22A5;SLCO2B1;SLC16A1;SLC5A8;SLC16A3 common genes common pathways GO:0007165| signal transduction HCAR2;HCAR3;MET 43492:[DB06314 DB00050] DB06314|SGX-523 MET DB00050|Cetrorelix GNRHR;LHCGR common genes common pathways GO:0007165| signal transduction LHCGR;MET;GNRHR 43493:[DB06314 DB00401] DB06314|SGX-523 MET DB00401|Nisoldipine CACNA1C;CACNA2D1;CACNB2;CACNA1D;CACNA1S;CYP3A4;CYP3A5;CYP3A7;ABCB1 common genes common pathways 43494:[DB06314 DB01054] DB06314|SGX-523 MET DB01054|Nitrendipine CACNA1C;CACNA2D1;CACNB2;CACNG1;CACNA1D;CACNA1S;CACNA2D2;CACNA1H;CYP3A4;CYP3A5;CYP3A7;ABCB1;ABCB11 common genes common pathways 43495:[DB06314 DB05983] DB06314|SGX-523 MET DB05983|Bardoxolone methyl NFKBIA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NFKBIA 43496:[DB06314 DB09336] DB06314|SGX-523 MET DB09336|Technetium Tc-99m nofetumomab merpentan EPCAM;MS4A1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter EPCAM;MET 43497:[DB06314 DB04100] DB06314|SGX-523 MET DB04100|(1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I) ABCC2 common genes common pathways 43498:[DB06314 DB00126] DB06314|SGX-523 MET DB00126|Ascorbic acid LCT;xylA;PLOD2;PHYH;PLOD3;BBOX1;DBH;PAM;P4HA1;P3H1;OGFOD2;ALKBH2;P3H2;P3H3;OGFOD1;EGLN2;ALKBH3;KDM5D;EGLN1;SLC23A1;PLOD1;EGLN3;TMLHE;P4HTM;SLC23A1 common genes common pathways GO:0001886| endothelial cell morphogenesis PLOD3;MET GO:0008283| cell proliferation MET;OGFOD1;ALKBH3 GO:0045944| positive regulation of transcription from RNA polymerase II promoter EGLN1;MET 43499:[DB06314 DB01274] DB06314|SGX-523 MET DB01274|Arformoterol ADRB2;CYP2D6;CYP2C19;CYP2A6;CYP2C9 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ADRB2 GO:0007165| signal transduction ADRB2;MET GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET 43500:[DB06314 DB09413] DB06314|SGX-523 MET DB09413|Monopotassium phosphate ALPI common genes common pathways 43501:[DB06314 DB06360] DB06314|SGX-523 MET DB06360|Lucatumumab CD40 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter CD40;MET 43502:[DB06314 DB00035] DB06314|SGX-523 MET DB00035|Desmopressin AVPR2;AVPR1A;AVPR1B;PTGS1;PTGS2 common genes common pathways GO:0007165| signal transduction AVPR1A;AVPR2;MET;AVPR1B 43503:[DB06314 DB02745] DB06314|SGX-523 MET DB02745|Uridine LSM6;SLC29A1 common genes common pathways 43504:[DB06314 DB00669] DB06314|SGX-523 MET DB00669|Sumatriptan HTR1D;HTR1B;HTR1F;HTR1A;MAOA;SLCO1A2;ABCB1;ABCG2;SLCO1B1 common genes common pathways GO:0008283| cell proliferation HTR1A;MET GO:0007165| signal transduction MET;HTR1F;HTR1B;HTR1D;HTR1A 43505:[DB06314 DB09217] DB06314|SGX-523 MET DB09217|Firocoxib PTGS2 common genes common pathways 43506:[DB06314 DB01151] DB06314|SGX-523 MET DB01151|Desipramine SLC6A2;SLC6A4;HTR2A;ADRB2;ADRB1;SMPD1;HRH1;ADRA1A;ADRA1B;ADRA1D;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR1A;HTR2C;DRD2;ADRA2A;ADRA2B;ADRA2C;CYP2D6;CYP2C19;CYP2C18;CYP1A2;CYP3A4;CYP2A6;CYP2B6;CYP2E1;ORM1;ABCB1;SLC22A1;SLC22A2;SLC22A3;SLC22A5;SLC22A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET;CHRM4 GO:0008283| cell proliferation CHRM1;CHRM4;ADRA1D;MET;CHRM5;CHRM3;ADRA1B;HTR1A GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction CHRM3;HTR2C;ADRA2A;HRH1;CHRM5;MET;ADRB2;CHRM2;ADRA2C;ADRA1D;CHRM4;CHRM1;ADRA1A;DRD2;ADRA2B;HTR2A;SMPD1;ADRB1;HTR1A;ADRA1B 43507:[DB06314 DB00430] DB06314|SGX-523 MET DB00430|Cefpiramide mrcA;mrcA;ALB common genes common pathways 43508:[DB06314 DB03506] DB06314|SGX-523 MET DB03506|9-Deazaadenine APRT common genes common pathways 43509:[DB06314 DB12119] DB06314|SGX-523 MET DB12119|Gevokizumab IL1B common genes common pathways GO:0007165| signal transduction MET;IL1B GO:0000165| MAPKKK cascade IL1B;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter IL1B;MET 43510:[DB06314 DB06636] DB06314|SGX-523 MET DB06636|Isavuconazonium CYP3A4;ABCB1 common genes common pathways 43511:[DB06314 DB00081] DB06314|SGX-523 MET DB00081|Tositumomab MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction FCGR2B;FCGR2C;FCGR1A;MET 43512:[DB06314 DB08049] DB06314|SGX-523 MET DB08049|7,8-dihydroxy-4-phenyl-2H-chromen-2-one COMT common genes common pathways 43513:[DB06314 DB11198] DB06314|SGX-523 MET DB11198|Peppermint oil CYP1A2;CYP3A4 common genes common pathways 43514:[DB06314 DB01330] DB06314|SGX-523 MET DB01330|Cefotetan ALB common genes common pathways 43515:[DB06314 DB00490] DB06314|SGX-523 MET DB00490|Buspirone HTR1A;DRD2;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET GO:0007165| signal transduction HTR1A;DRD2;MET GO:0008283| cell proliferation MET;HTR1A 43516:[DB06314 DB12474] DB06314|SGX-523 MET DB12474|Lynestrenol CYP3A4;CYP2C9;CYP2C19 common genes common pathways 43517:[DB06314 DB01043] DB06314|SGX-523 MET DB01043|Memantine GRIN3A;GRIN2A;GRIN2B;HTR3A;CHRNA7;DRD2;GRIN1;CYP2B6;CYP2A6;CYP2C19;SLC22A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;GRIN1;DRD2 GO:0000165| MAPKKK cascade GRIN2A;GRIN2B;MET;GRIN1 GO:0007165| signal transduction MET;DRD2;HTR3A;CHRNA7 43518:[DB06314 DB09194] DB06314|SGX-523 MET DB09194|Etoperidone ADRA1A;ADRA1B;ADRA1D;ADRA2A;ADRA2B;ADRA2C;DRD2;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;HTR2A;HTR2C;SLC6A4;SLC6A2;SLC6A3 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD2 GO:0007166| cell surface receptor linked signaling pathway MET;CHRM4 GO:0008283| cell proliferation ADRA1B;CHRM4;ADRA1D;CHRM1;CHRM3;CHRM5;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1B;ADRA2B;HTR2A;ADRA1A;DRD2;CHRM1;ADRA1D;CHRM4;ADRA2C;CHRM2;CHRM5;MET;CHRM3;ADRA2A;HTR2C 43519:[DB06314 DB00968] DB06314|SGX-523 MET DB00968|Methyldopa ADRA2A;DDC;COMT;SLC15A1 common genes common pathways GO:0007165| signal transduction ADRA2A;MET 43520:[DB06314 DB00910] DB06314|SGX-523 MET DB00910|Paricalcitol VDR;CYP24A1;CYP3A4;UGT1A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter VDR;MET GO:0007165| signal transduction MET;VDR 43521:[DB06314 DB08952] DB06314|SGX-523 MET DB08952|Indenolol CYP2D6 common genes common pathways 43522:[DB06314 DB01107] DB06314|SGX-523 MET DB01107|Methyprylon GABRA1;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ common genes common pathways GO:0007165| signal transduction GABRD;GABRB1;GABRA6;GABRA5;GABRP;GABRQ;GABRE;GABRB3;MET 43523:[DB06314 DB01076] DB06314|SGX-523 MET DB01076|Atorvastatin HMGCR;DPP4;AHR;CYP3A4;CYP3A5;CYP3A7;CYP2C8;CYP2D6;CYP2C9;CYP2C19;CYP2B6;UGT1A1;UGT1A3;UGT2B7;ABCB1;SLCO1A2;SLCO1B1;ABCC4;ABCC5;ABCC1;SLCO2B1;SLCO1B3;ABCC2;ABCB11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;AHR 43524:[DB06314 DB09073] DB06314|SGX-523 MET DB09073|Palbociclib CDK4;CDK6;CYP3A4 common genes common pathways GO:0007165| signal transduction CDK6;CDK4;MET GO:0006468| protein phosphorylation CDK6;CDK4;MET GO:0016310| phosphorylation CDK4;CDK6;MET 43525:[DB06314 DB08816] DB06314|SGX-523 MET DB08816|Ticagrelor P2RY12;CYP3A4;CYP2D6;CYP2C9;ABCB1 common genes common pathways GO:0007165| signal transduction P2RY12;MET 43526:[DB06314 DB00424] DB06314|SGX-523 MET DB00424|Hyoscyamine CHRM1;CHRM2;CHRM3;CHRM4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET GO:0008283| cell proliferation CHRM4;CHRM1;CHRM3;MET GO:0007165| signal transduction CHRM1;CHRM4;CHRM2;MET;CHRM3 43527:[DB06314 DB09045] DB06314|SGX-523 MET DB09045|Dulaglutide GLP1R common genes common pathways GO:0007165| signal transduction GLP1R;MET GO:0007166| cell surface receptor linked signaling pathway MET;GLP1R 43528:[DB06314 DB00706] DB06314|SGX-523 MET DB00706|Tamsulosin ADRA1A;ADRA1D;ADRA1B;CYP3A4;CYP2D6;ORM1 common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction ADRA1B;ADRA1A;ADRA1D;MET GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1B;ADRA1D;MET 43529:[DB06314 DB06307] DB06314|SGX-523 MET DB06307|Apoptone BCL2 common genes common pathways GO:0008283| cell proliferation BCL2;MET GO:0010507| negative regulation of autophagy MET;BCL2 43530:[DB06314 DB01418] DB06314|SGX-523 MET DB01418|Acenocoumarol VKORC1;CYP2C9;CYP1A2;CYP2C19;CYP3A4;ALB;ORM1 common genes common pathways 43531:[DB06314 DB09105] DB06314|SGX-523 MET DB09105|Asfotase Alfa S1PR1 common genes common pathways GO:0051497| negative regulation of stress fiber assembly MET;S1PR1 GO:0007165| signal transduction MET;S1PR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter S1PR1;MET 43532:[DB06314 DB09299] DB06314|SGX-523 MET DB09299|Tenofovir alafenamide pol;ABCB1 common genes common pathways 43533:[DB06314 DB12130] DB06314|SGX-523 MET DB12130|Lorlatinib ALK;CYP3A5;CYP2B6;CYP2C8;CYP2C19;UGT1A3 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation MET;ALK GO:0008283| cell proliferation MET;ALK GO:0016310| phosphorylation MET;ALK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;ALK GO:0006468| protein phosphorylation MET;ALK GO:0007165| signal transduction MET;ALK 43534:[DB06314 DB00356] DB06314|SGX-523 MET DB00356|Chlorzoxazone KCNMA1;CYP2E1;CYP1A1;CYP1A2;CYP2A6;CYP3A4;CYP2D6 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 43535:[DB06314 DB09039] DB06314|SGX-523 MET DB09039|Eliglustat UGCG;CYP2D6;CYP3A4 common genes common pathways 43536:[DB06314 DB04620] DB06314|SGX-523 MET DB04620|Cycloleucine GRIN1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter GRIN1;MET GO:0000165| MAPKKK cascade MET;GRIN1 43537:[DB06314 DB01332] DB06314|SGX-523 MET DB01332|Ceftizoxime mrcA;SLC15A1;SLC22A6;SLC22A8 common genes common pathways 43538:[DB06314 DB06016] DB06314|SGX-523 MET DB06016|Cariprazine DRD3;DRD2;HTR1A;HTR2B;HTR2A;HRH1;CYP3A4;CYP2D6 common genes common pathways GO:0008283| cell proliferation MET;HTR1A GO:0010507| negative regulation of autophagy MET;HTR2B GO:0007165| signal transduction DRD3;HRH1;MET;HTR1A;HTR2B;HTR2A;DRD2 GO:0016310| phosphorylation HTR2B;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;MET;DRD2 43539:[DB06314 DB09289] DB06314|SGX-523 MET DB09289|Tianeptine GRIA1;OPRM1;HTR1A;DRD3;CYP3A4 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD3 GO:0007165| signal transduction MET;GRIA1;DRD3;OPRM1;HTR1A GO:0008283| cell proliferation MET;HTR1A 43540:[DB06314 DB04519] DB06314|SGX-523 MET DB04519|Caprylic acid fabB;tesA;PPARA;SLC22A6;SLC22A8;SLC22A11 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARA 43541:[DB06314 DB00322] DB06314|SGX-523 MET DB00322|Floxuridine TYMS;TYMP;CYP2C9 common genes common pathways 43542:[DB06314 DB03664] DB06314|SGX-523 MET DB03664|UP5 CMPK1 common genes common pathways GO:0016310| phosphorylation MET;CMPK1 43543:[DB06314 DB01216] DB06314|SGX-523 MET DB01216|Finasteride SRD5A2;SRD5A1;AKR1D1;CYP3A5;CYP3A7;CYP3A4 common genes common pathways 43544:[DB06314 DB06730] DB06314|SGX-523 MET DB06730|Gestodene PGR;CYP3A5;CYP3A7;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;PGR GO:0045944| positive regulation of transcription from RNA polymerase II promoter PGR;MET 43545:[DB06314 DB00191] DB06314|SGX-523 MET DB00191|Phentermine SLC6A2;SLC6A4;SLC6A3;MAOA;MAOB;MAOA;MAOB;CYP1A2 common genes common pathways 43546:[DB06314 DB06650] DB06314|SGX-523 MET DB06650|Ofatumumab MS4A1 common genes common pathways 43547:[DB06314 DB00371] DB06314|SGX-523 MET DB00371|Meprobamate GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2E1 common genes common pathways GO:0007165| signal transduction GABRQ;GABRE;GABRP;GABRB3;MET;GABRB1;GABRA6;GABRD;GABRA5 43548:[DB06314 DB06684] DB06314|SGX-523 MET DB06684|Vilazodone HTR1A;CYP3A4;CYP2C18;CYP2D6;SLC6A4 common genes common pathways GO:0008283| cell proliferation MET;HTR1A GO:0007165| signal transduction MET;HTR1A 43549:[DB06314 DB00530] DB06314|SGX-523 MET DB00530|Erlotinib EGFR;NR1I2;CYP3A4;CYP3A5;CYP1A2;CYP1A1;CYP2D6;CYP2C8;CYP1B1;UGT1A1;ALB;ORM1;ABCG2;ABCB1;SLCO2B1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway EGFR;MET GO:0018108| peptidyl-tyrosine phosphorylation EGFR;MET GO:0000165| MAPKKK cascade EGFR;MET GO:0016310| phosphorylation MET;EGFR GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway MET;EGFR GO:0006468| protein phosphorylation EGFR;MET GO:0007165| signal transduction MET;NR1I2;EGFR GO:0008283| cell proliferation MET;CYP1A1;EGFR GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR1I2;EGFR GO:0051897| positive regulation of protein kinase B signaling cascade MET;EGFR GO:0046854| phosphatidylinositol phosphorylation EGFR;MET 43550:[DB06314 DB00931] DB06314|SGX-523 MET DB00931|Metacycline ALB common genes common pathways 43551:[DB06314 DB00903] DB06314|SGX-523 MET DB00903|Etacrynic acid ATP1A1;SLC12A1;LEF1;GSTP1;GSTA2;ALB;SLC22A6 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter LEF1;MET 43552:[DB06314 DB07789] DB06314|SGX-523 MET DB07789|1-[5-methyl-2-(trifluoromethyl)furan-3-yl]-3-[(2Z)-5-(2-{[6-(1H-1,2,4-triazol-3-ylamino)pyrimidin-4-yl]amino}ethyl)-1,3-thiazol-2(3H)-ylidene]urea PLK1 common genes common pathways GO:0008283| cell proliferation PLK1;MET GO:0006468| protein phosphorylation PLK1;MET GO:0016310| phosphorylation PLK1;MET 43553:[DB06314 DB01089] DB06314|SGX-523 MET DB01089|Deserpidine SLC18A2 common genes common pathways 43554:[DB06314 DB13166] DB06314|SGX-523 MET DB13166|Zofenopril ACE common genes common pathways 43555:[DB06314 DB01223] DB06314|SGX-523 MET DB01223|Aminophylline PDE3A;ADORA1;ADORA3;HDAC2;CYP1A2;CYP2E1;CYP3A4;CYP2C19 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;HDAC2 GO:0007165| signal transduction MET;ADORA1;ADORA3;PDE3A 43556:[DB06314 DB00995] DB06314|SGX-523 MET DB00995|Auranofin PRDX5;IKBKB;ALB common genes common pathways GO:0006468| protein phosphorylation MET;IKBKB GO:0016310| phosphorylation IKBKB;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;IKBKB 43557:[DB06314 DB00108] DB06314|SGX-523 MET DB00108|Natalizumab ITGA4;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;FCGR1A;FCGR2A;FCGR2B;FCGR2C;ICAM1 common genes common pathways GO:0007165| signal transduction FCGR2B;FCGR2C;FCGR1A;MET 43558:[DB06314 DB09236] DB06314|SGX-523 MET DB09236|Lacidipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4;ALB;ORM1 common genes common pathways 43559:[DB06314 DB08930] DB06314|SGX-523 MET DB08930|Dolutegravir pol;UGT1A1;CYP3A4;CYP3A43;CYP3A5;CYP3A7;UGT1A3;UGT1A9;ABCB1;SLC22A2;ABCG2;SLC22A6;SLC22A8 common genes common pathways 43560:[DB06314 DB11858] DB06314|SGX-523 MET DB11858|Leukotriene D4 CYSLTR1;CYSLTR2 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CYSLTR1 GO:0007165| signal transduction MET;CYSLTR1;CYSLTR2 43561:[DB06314 DB14132] DB06314|SGX-523 MET DB14132|8-chlorotheophylline ADORA2A;CYP1A2 common genes common pathways GO:0007165| signal transduction ADORA2A;MET 43562:[DB06314 DB09070] DB06314|SGX-523 MET DB09070|Tibolone ESR1;STS;HSD3B1;HSD3B2;SULT1A1 common genes common pathways GO:0007165| signal transduction MET;ESR1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;ESR1 43563:[DB06314 DB04905] DB06314|SGX-523 MET DB04905|Tesmilifene ABCB1;HRH1;CYP3A4;CYP2D6;CYP1A1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction HRH1;MET 43564:[DB06314 DB00487] DB06314|SGX-523 MET DB00487|Pefloxacin parC;gyrA;TOP2A;topA;CYP1A2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43565:[DB06314 DB13881] DB06314|SGX-523 MET DB13881|Tisagenlecleucel CD19 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CD19 GO:0051897| positive regulation of protein kinase B signaling cascade MET;CD19 GO:0046854| phosphatidylinositol phosphorylation CD19;MET 43566:[DB06314 DB00682] DB06314|SGX-523 MET DB00682|Warfarin VKORC1;NR1I2;CYP2C9;CYP1A2;CYP2C19;CYP3A4;CYP2C8;CYP2C18;CYP1A1;ALB;ORM1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET GO:0007165| signal transduction NR1I2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET 43567:[DB06314 DB05920] DB06314|SGX-523 MET DB05920|RTA 744 TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43568:[DB06314 DB11397] DB06314|SGX-523 MET DB11397|Dichlorvos TF;BCHE;ALB common genes common pathways 43569:[DB06314 DB01589] DB06314|SGX-523 MET DB01589|Quazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP2B6 common genes common pathways GO:0007165| signal transduction GABRP;GABRE;GABRQ;GABRB3;MET;GABRD;GABRR2;GABRA6;GABRB1;GABRA5 43570:[DB06314 DB00104] DB06314|SGX-523 MET DB00104|Octreotide SSTR1;SSTR5;SSTR2;MPO;CYP3A4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;SSTR1 GO:0007165| signal transduction MET;SSTR5;SSTR1;SSTR2 43571:[DB06314 DB01064] DB06314|SGX-523 MET DB01064|Isoprenaline ADRB1;ADRB2;ADRB3;MAPK1;PIK3R1;PIK3R2;PIK3R3;PDE4;SOD1;CYP1A1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0000165| MAPKKK cascade MET;MAPK1 GO:0007165| signal transduction PIK3R1;MAPK1;PIK3R2;ADRB2;MET;ADRB1;ADRB3 GO:0006468| protein phosphorylation PIK3R1;MAPK1;MET GO:0016310| phosphorylation MET;MAPK1 GO:0008283| cell proliferation MET;CYP1A1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET;PIK3R2;PIK3R1 GO:0051897| positive regulation of protein kinase B signaling cascade PIK3R1;PIK3R2;MET GO:0046854| phosphatidylinositol phosphorylation PIK3R1;MET;PIK3R2 43572:[DB06314 DB06414] DB06314|SGX-523 MET DB06414|Etravirine CYP3A4;CYP2C9;CYP2C19;ABCB1;ABCB4 common genes common pathways 43573:[DB06314 DB06538] DB06314|SGX-523 MET DB06538|Robalzotan HTR1A common genes common pathways GO:0007165| signal transduction HTR1A;MET GO:0008283| cell proliferation MET;HTR1A 43574:[DB06314 DB08190] DB06314|SGX-523 MET DB08190|N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide NQO2 common genes common pathways 43575:[DB06314 DB09280] DB06314|SGX-523 MET DB09280|Lumacaftor CFTR;CYP3A4;CYP2B6;CYP2C8;CYP2C9;CYP2C19;ALB;ABCB1 common genes common pathways 43576:[DB06314 DB00633] DB06314|SGX-523 MET DB00633|Dexmedetomidine ADRA2A;CYP2E1;CYP1A2;CYP1A1;CYP2D6 common genes common pathways GO:0007165| signal transduction ADRA2A;MET GO:0008283| cell proliferation MET;CYP1A1 43577:[DB06314 DB01349] DB06314|SGX-523 MET DB01349|Tasosartan AGTR1;AGTR2;CYP3A4 common genes common pathways GO:0007165| signal transduction AGTR2;AGTR1;MET GO:0007166| cell surface receptor linked signaling pathway AGTR2;MET 43578:[DB06314 DB11774] DB06314|SGX-523 MET DB11774|Pazufloxacin CYP1A2 common genes common pathways 43579:[DB06314 DB00471] DB06314|SGX-523 MET DB00471|Montelukast CYSLTR1;ALOX5;CYP2C8;CYP3A4;CYP2C9;PTGS1;CYP2A6;SLCO2B1 common genes common pathways GO:0007165| signal transduction CYSLTR1;MET GO:0007166| cell surface receptor linked signaling pathway CYSLTR1;MET 43580:[DB06314 DB01587] DB06314|SGX-523 MET DB01587|Ketazolam TSPO;GABRA1;GABRB1;GABRG1;GABRD;GABRE;CYP3A4;ALB;ABCB1 common genes common pathways GO:0008283| cell proliferation TSPO;MET GO:0007165| signal transduction GABRB1;GABRD;MET;TSPO;GABRE 43581:[DB06314 DB13500] DB06314|SGX-523 MET DB13500|Otilonium CYP3A4 common genes common pathways 43582:[DB06314 DB09154] DB06314|SGX-523 MET DB09154|Sodium Citrate SLC25A21;SLC13A2;SLC13A5;SLC25A1 common genes common pathways 43583:[DB06314 DB01231] DB06314|SGX-523 MET DB01231|Diphenidol CHRM1;CHRM3;CHRM2 common genes common pathways GO:0007165| signal transduction CHRM1;CHRM2;MET;CHRM3 GO:0008283| cell proliferation CHRM1;CHRM3;MET 43584:[DB06314 DB00710] DB06314|SGX-523 MET DB00710|Ibandronate FDPS common genes common pathways 43585:[DB06314 DB00917] DB06314|SGX-523 MET DB00917|Dinoprostone PTGER2;PTGER1;PTGER3;PTGER4;PTGDR2;CYP11A1;CYP19A1;SLC22A2;ABCC5;SLC22A6;SLC22A8;SLC22A11;SLC22A7;ABCC4;SLCO2B1;SLCO1A2;SLC51A;SLC51B;SLCO2A1;SLCO4A1;SLCO1C1;SLCO3A1;SLCO1B1 common genes common pathways GO:0007165| signal transduction PTGER1;PTGER2;PTGDR2;PTGER4;PTGER3;MET 43586:[DB06314 DB01583] DB06314|SGX-523 MET DB01583|Liotrix THRA;THRB;CYP2C8;CYP3A4;TTR;SERPINA7;ALB;SLCO1A2;SLCO1B1;SLCO1B3;SLCO4C1;SLC10A1;SLCO1C1;SLCO4A1;SLC22A8;SLC16A2;SLC16A10;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;THRB;THRA 43587:[DB06314 DB00331] DB06314|SGX-523 MET DB00331|Metformin PRKAB1;SLC22A1;SLC22A2;SLC22A3;SLC47A1;SLC29A4;SLC47A2 common genes common pathways GO:0006468| protein phosphorylation PRKAB1;MET GO:0007165| signal transduction MET;PRKAB1 43588:[DB06314 DB07700] DB06314|SGX-523 MET DB07700|3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN AKR1C3 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;AKR1C3 43589:[DB06314 DB04951] DB06314|SGX-523 MET DB04951|Pirfenidone FURIN;CYP1A2 common genes common pathways GO:0008283| cell proliferation FURIN;MET 43590:[DB06314 DB09230] DB06314|SGX-523 MET DB09230|Azelnidipine CACNB1;CYP3A4 common genes common pathways 43591:[DB06314 DB01264] DB06314|SGX-523 MET DB01264|Darunavir pol;CYP3A4;SLCO1B1;ABCB1 common genes common pathways 43592:[DB06314 DB00850] DB06314|SGX-523 MET DB00850|Perphenazine DRD2;DRD1;CALM1;CYP2D6;CYP1A2;CYP2B6;CYP2C18;CYP2C19;CYP2C8;CYP2C9;CYP3A4 common genes common pathways GO:0007165| signal transduction DRD2;DRD1;MET GO:0000165| MAPKKK cascade MET;CALM1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET 43593:[DB06314 DB04957] DB06314|SGX-523 MET DB04957|Azimilide KCNE1;KCNQ1;KCNH2;CYP1A1;CYP3A4;CYP3A5 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 43594:[DB06314 DB05679] DB06314|SGX-523 MET DB05679|Ustekinumab IL12B;IL12B;IL23A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;IL23A GO:0007166| cell surface receptor linked signaling pathway IL12B;MET GO:0008283| cell proliferation IL12B;MET 43595:[DB06314 DB13203] DB06314|SGX-523 MET DB13203|Bamifylline CYP1A2 common genes common pathways 43596:[DB06314 DB06479] DB06314|SGX-523 MET DB06479|Propentofylline PDE4A;CYP1A2 common genes common pathways GO:0007165| signal transduction PDE4A;MET 43597:[DB06314 DB11760] DB06314|SGX-523 MET DB11760|Talazoparib PARP1;PARP2;ABCB1;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PARP1 43598:[DB06314 DB01456] DB06314|SGX-523 MET DB01456|5-androstenedione CYP3A4 common genes common pathways 43599:[DB06314 DB02691] DB06314|SGX-523 MET DB02691|Glycocholic acid FABP6;SLCO1A2;SLCO1B1;SLCO1B3 common genes common pathways 43600:[DB06314 DB01399] DB06314|SGX-523 MET DB01399|Salsalate PTGS2;PTGS1 common genes common pathways 43601:[DB06314 DB05514] DB06314|SGX-523 MET DB05514|Cobiprostone CLCN2 common genes common pathways 43602:[DB06314 DB01559] DB06314|SGX-523 MET DB01559|Clotiazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRG1;GABRG2;GABRG3;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;CYP2B6;CYP2C18;CYP2C19;CYP3A4 common genes common pathways GO:0007165| signal transduction GABRP;GABRE;MET;GABRB3;GABRR2;GABRD;GABRB1;GABRA5 43603:[DB06314 DB09091] DB06314|SGX-523 MET DB09091|Tixocortol NR3C1;HDAC2 common genes common pathways GO:0007165| signal transduction NR3C1;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1;HDAC2 43604:[DB06314 DB04794] DB06314|SGX-523 MET DB04794|Bifonazole CYP2B6;CYP19A1;CYP2E1;CYP3A4 common genes common pathways 43605:[DB06314 DB12141] DB06314|SGX-523 MET DB12141|Gilteritinib FLT3;HTR1A;HTR1B;HTR1D;HTR1E;HTR1F;HTR2A;HTR2B;HTR2C;HTR3A;HTR3B;HTR3C;HTR3D;HTR3E;HTR4;HTR6;HTR7;AXL;ALK;CYP3A4;ALB;ABCB1;SLC47A1;ABCG2;SLC22A1 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation FLT3;MET;ALK;AXL GO:0010507| negative regulation of autophagy HTR2B;MET GO:0008283| cell proliferation HTR1A;ALK;MET GO:0007165| signal transduction HTR3C;HTR2A;ALK;HTR3B;HTR3A;HTR1A;HTR1D;AXL;HTR2B;MET;HTR3D;HTR3E;HTR2C;HTR6;HTR1F;HTR4;HTR1E;HTR1B;HTR7 GO:0006468| protein phosphorylation FLT3;MET;AXL;ALK GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT3;MET;ALK GO:0016310| phosphorylation MET;FLT3;ALK;AXL;HTR2B GO:0051897| positive regulation of protein kinase B signaling cascade MET;AXL 43606:[DB06314 DB00769] DB06314|SGX-523 MET DB00769|Hydrocortamate NR3C1;CYP3A4 common genes common pathways GO:0007165| signal transduction MET;NR3C1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;NR3C1 43607:[DB06314 DB00252] DB06314|SGX-523 MET DB00252|Phenytoin SCN5A;SCN1A;NR1I2;SCN1B;SCN3A;CYP2C9;CYP2C19;CYP2C8;CYP2B6;CYP3A4;CYP2C18;CYP3A5;CYP3A7;CYP11B1;UGT1A1;UGT1A6;UGT1A9;CYP2D6;ALB;SLCO1C1;ABCB1;ABCC2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET GO:0007165| signal transduction NR1I2;MET 43608:[DB06314 DB00078] DB06314|SGX-523 MET DB00078|Ibritumomab tiuxetan MS4A1;FCGR3B;C1R;C1QA;C1QB;C1QC;FCGR3A;C1S;FCGR1A;FCGR2A;FCGR2B;FCGR2C common genes common pathways GO:0007165| signal transduction FCGR1A;MET;FCGR2B;FCGR2C 43609:[DB06314 DB09140] DB06314|SGX-523 MET DB09140|Oxygen MT-CO1;NOX1;HBA1;HBB common genes common pathways GO:0007165| signal transduction NOX1;MET 43610:[DB06314 DB04946] DB06314|SGX-523 MET DB04946|Iloperidone HTR2A;DRD2;DRD1;DRD3;DRD4;HTR1A;HTR6;HTR7;ADRA1A;HRH1;ADRA2C;CYP2D6;CYP3A4;CYP3A5;CYP3A7;CYP2E1 common genes common pathways GO:0008283| cell proliferation HTR1A;MET GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction DRD2;ADRA1A;DRD4;HTR2A;DRD1;HTR1A;HTR6;MET;HRH1;ADRA2C;DRD3;HTR7 GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET;DRD3 43611:[DB06314 DB11614] DB06314|SGX-523 MET DB11614|Rupatadine PTAFR;HRH1;CYP3A4;CYP2C9;CYP2C19;CYP2D6 common genes common pathways GO:0007165| signal transduction PTAFR;HRH1;MET 43612:[DB06314 DB14064] DB06314|SGX-523 MET DB14064|Emopamil ABCB1;CYP3A4 common genes common pathways 43613:[DB06314 DB06814] DB06314|SGX-523 MET DB06814|Protokylol ADRB2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007165| signal transduction MET;ADRB2 GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET 43614:[DB06314 DB07919] DB06314|SGX-523 MET DB07919|7-METHOXY-1-METHYL-9H-BETA-CARBOLINE MAOA common genes common pathways 43615:[DB06314 DB09064] DB06314|SGX-523 MET DB09064|Ciprofibrate PPARA common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARA 43616:[DB06314 DB06145] DB06314|SGX-523 MET DB06145|Spiramycin rplC;CYP3A4 common genes common pathways 43617:[DB06314 DB12118] DB06314|SGX-523 MET DB12118|Sotatercept ACVR2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ACVR2A;MET GO:0016310| phosphorylation MET;ACVR2A GO:0006468| protein phosphorylation ACVR2A;MET 43618:[DB06314 DB00773] DB06314|SGX-523 MET DB00773|Etoposide TOP2A;TOP2B;CYP3A4;CYP1A2;CYP2C8;CYP2E1;CYP3A5;UGT1A1;GSTT1;GSTP1;PTGS2;PTGS1;ABCC3;ABCC6;ABCB1;ABCC1;ABCC10;ABCC2;ABCG2 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 43619:[DB06314 DB00580] DB06314|SGX-523 MET DB00580|Valdecoxib PTGS2;CA2;CA3;CYP3A4;CYP2C9;UGT1A9 common genes common pathways 43620:[DB06314 DB00515] DB06314|SGX-523 MET DB00515|Cisplatin MPG;A2M;TF;ATOX1;MPO;XDH;CYP4A11;PTGS2;CYP2C9;CYP2B6;BCHE;GSTT1;MT1A;MT2A;SOD1;GSTP1;NQO1;GSTM1;ALB;ABCC3;ABCC5;ABCC2;SLC22A2;SLC31A1;SLC31A2;ABCC6;ABCB1;ATP7B;ATP7A;ABCG2 common genes common pathways 43621:[DB06314 DB00794] DB06314|SGX-523 MET DB00794|Primidone GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;CHRNA4;CHRNA7;GRIA2;GRIK2;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP2C19;CYP2C9;CYP3A4;CYP1A2;CYP2B6;CYP2C8;UGT1A1 common genes common pathways GO:0007165| signal transduction GABRP;GABRE;GABRQ;GABRB3;GRIA2;MET;GABRD;CHRNA7;CHRNA4;GABRA6;GABRB1;GABRA5 43622:[DB06314 DB00178] DB06314|SGX-523 MET DB00178|Ramipril ACE;BDKRB1;BCHE;SLC15A1;SLC15A2 common genes common pathways GO:0007165| signal transduction BDKRB1;MET 43623:[DB06314 DB00592] DB06314|SGX-523 MET DB00592|Piperazine GABRB3;CYP2D6 common genes common pathways GO:0007165| signal transduction GABRB3;MET 43624:[DB06314 DB09227] DB06314|SGX-523 MET DB09227|Barnidipine CACNA1C;CYP3A4 common genes common pathways 43625:[DB06314 DB00815] DB06314|SGX-523 MET DB00815|Sodium lauryl sulfate ALB common genes common pathways 43626:[DB06314 DB00839] DB06314|SGX-523 MET DB00839|Tolazamide ABCC8;KCNJ11;CYP2C9 common genes common pathways GO:0007165| signal transduction ABCC8;MET 43627:[DB06314 DB00925] DB06314|SGX-523 MET DB00925|Phenoxybenzamine ADRA1A;ADRA2A;ADRA2C;ADRA2B;CALM1;ADRB2;ADRA1B;ADRA1D;SLC22A2;SLC22A1;SLC22A3 common genes common pathways GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation ADRA1D;MET;ADRA1B GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0007165| signal transduction ADRA1D;MET;ADRB2;ADRA2C;ADRA2A;ADRA1B;ADRA2B;ADRA1A GO:0000165| MAPKKK cascade CALM1;MET GO:0007166| cell surface receptor linked signaling pathway ADRB2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43628:[DB06314 DB12418] DB06314|SGX-523 MET DB12418|Saccharin CA3 common genes common pathways 43629:[DB06314 DB00449] DB06314|SGX-523 MET DB00449|Dipivefrin ADRA1A;ADRA2A;ADRB2;BCHE;ACHE common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0008283| cell proliferation MET;ACHE GO:0007165| signal transduction ADRA1A;ADRB2;MET;ADRA2A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43630:[DB06314 DB12061] DB06314|SGX-523 MET DB12061|Pardoprunox DRD2;DRD3;DRD4;HTR1A common genes common pathways GO:0007165| signal transduction DRD3;MET;HTR1A;DRD4;DRD2 GO:0008283| cell proliferation MET;HTR1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;DRD3;MET 43631:[DB06314 DB06215] DB06314|SGX-523 MET DB06215|Ferumoxytol TF;FTL;FTH1 common genes common pathways 43632:[DB06314 DB09167] DB06314|SGX-523 MET DB09167|Dosulepin HTR1A;HTR2A;HRH1;CHRM1;CHRM2;CHRM3;CHRM4;CHRM5;ADRA2A;ADRA2B;ADRA2C;ADRA1A;ADRA1B;ADRA1D;SLC6A2;SLC6A4;CYP2D6;CYP1A2;CYP2C19;CYP2C9 common genes common pathways GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation HTR1A;ADRA1B;ADRA1D;CHRM4;CHRM1;CHRM3;CHRM5;MET GO:0007165| signal transduction ADRA1D;CHRM4;CHRM1;CHRM3;ADRA2A;HRH1;CHRM5;MET;CHRM2;ADRA2C;HTR1A;ADRA1B;ADRA1A;ADRA2B;HTR2A GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007166| cell surface receptor linked signaling pathway CHRM4;MET 43633:[DB06314 DB00446] DB06314|SGX-523 MET DB00446|Chloramphenicol rplP;CD55;CYP3A4;CYP3A5;CYP3A7;CYP2C19;cat;CYP2C8;SLC22A6 common genes common pathways 43634:[DB06314 DB01973] DB06314|SGX-523 MET DB01973|O-Benzylsulfonyl-Serine PRSS2 common genes common pathways 43635:[DB06314 DB00373] DB06314|SGX-523 MET DB00373|Timolol ADRB1;ADRB2;CYP2D6;CYP2C19;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET GO:0007165| signal transduction ADRB2;MET;ADRB1 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 43636:[DB06314 DB09462] DB06314|SGX-523 MET DB09462|Glycerin PPARD;HPGDS;GSTP1;PLA2G2E;ISYNA1;dctD;ADH1B;ITPR1;PAEP;NAGA;bfr;TGFBR2;argG;eno;ARF1;PAPSS1;hisD;mutL;TRDMT1;ALDH1A1;CYP2E1 common genes common pathways GO:0006468| protein phosphorylation MET;TGFBR2 GO:0016310| phosphorylation MET;PAPSS1;TGFBR2 GO:0007165| signal transduction MET;HPGDS;ITPR1 GO:0008283| cell proliferation PPARD;MET 43637:[DB06314 DB02508] DB06314|SGX-523 MET DB02508|Isopentyl Pyrophosphate ispA;FDPS;ispA common genes common pathways 43638:[DB06314 DB00319] DB06314|SGX-523 MET DB00319|Piperacillin SLC22A6;SLC22A8 common genes common pathways 43639:[DB06314 DB00393] DB06314|SGX-523 MET DB00393|Nimodipine CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;NR3C2;AHR;CYP3A4;CYP3A5 common genes common pathways GO:0007165| signal transduction NR3C2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter AHR;MET 43640:[DB06314 DB00716] DB06314|SGX-523 MET DB00716|Nedocromil CYSLTR1;CYSLTR2;FPR1;PTGDR;HSP90AA1 common genes common pathways GO:0007165| signal transduction FPR1;CYSLTR2;HSP90AA1;PTGDR;CYSLTR1;MET GO:0018108| peptidyl-tyrosine phosphorylation MET;HSP90AA1 GO:0007166| cell surface receptor linked signaling pathway CYSLTR1;MET 43641:[DB06314 DB00825] DB06314|SGX-523 MET DB00825|Levomenthol TRPM8;TRPA1;TRPV3;OPRK1;CACNA1C;CACNA1D;CACNA1F;CACNA1S;CACNB1;CACNB2;CACNB3;CACNB4;CYP3A4 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;TRPA1 GO:0007165| signal transduction OPRK1;MET 43642:[DB06314 DB01105] DB06314|SGX-523 MET DB01105|Sibutramine SLC6A2;SLC6A4;SLC6A3;CYP3A4 common genes common pathways 43643:[DB06314 DB00030] DB06314|SGX-523 MET DB00030|Insulin Human INSR;IGF1R;RB1;CTSD;IDE;PCSK2;CPE;PCSK1;NOV;LRP2;IGFBP7;SYTL4 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation MET;INSR GO:0006468| protein phosphorylation MET;INSR;IGF1R GO:0016310| phosphorylation MET;INSR;IGF1R GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway INSR;MET;IGF1R GO:0007165| signal transduction IGF1R;MET GO:0008283| cell proliferation LRP2;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;RB1 GO:0051897| positive regulation of protein kinase B signaling cascade MET;INSR 43644:[DB06314 DB00207] DB06314|SGX-523 MET DB00207|Azithromycin rplD;rplV;PADI4;CYP3A4;CYP2A6;ABCB1 common genes common pathways 43645:[DB06314 DB01128] DB06314|SGX-523 MET DB01128|Bicalutamide AR;CYP3A4;CYP2C19;CYP2C9;CYP2D6 common genes common pathways GO:0007165| signal transduction AR;MET GO:0008283| cell proliferation AR;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter AR;MET 43646:[DB06314 DB06290] DB06314|SGX-523 MET DB06290|Simeprevir CYP1A2;CYP3A4;ALB;ABCB1;SLCO1B1;SLCO1B3;ABCC2;ABCG2;SLCO2B1;SLC10A1;ABCB11 common genes common pathways 43647:[DB06314 DB13967] DB06314|SGX-523 MET DB13967|Patent Blue ALB common genes common pathways 43648:[DB06314 DB06287] DB06314|SGX-523 MET DB06287|Temsirolimus MTOR;CYP3A4;CYP3A5;CYP3A7;CYP2D6;ABCB1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MTOR;MET GO:0007165| signal transduction MET;MTOR GO:0006468| protein phosphorylation MTOR;MET GO:0016310| phosphorylation MET;MTOR GO:0010507| negative regulation of autophagy MET;MTOR 43649:[DB06314 DB13884] DB06314|SGX-523 MET DB13884|Albutrepenonacog alfa F10;F8 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;F10 43650:[DB06314 DB11995] DB06314|SGX-523 MET DB11995|Avatrombopag ABCG2;MPL;SLC22A8;CYP2C8;CYP2C9;ABCB1 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MPL;MET GO:0008283| cell proliferation MET;MPL 43651:[DB06314 DB06457] DB06314|SGX-523 MET DB06457|Tecastemizole KCNH2 common genes common pathways 43652:[DB06314 DB07117] DB06314|SGX-523 MET DB07117|5-(4-PHENOXYPHENYL)-5-(4-PYRIMIDIN-2-YLPIPERAZIN-1-YL)PYRIMIDINE-2,4,6(2H,3H)-TRIONE MMP9 common genes common pathways 43653:[DB06314 DB00829] DB06314|SGX-523 MET DB00829|Diazepam GABRA1;GABRA2;GABRA3;GABRA5;GABRB1;GABRB2;GABRB3;GABRG1;GABRG2;GABRG3;GABRD;GABRE;GABRP;GABRR1;GABRR2;GABRR3;GABRQ;TSPO;GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;CYP3A4;CYP3A5;CYP3A7;CYP2C19;CYP2C9;CYP2B6;CYP2C18;CYP2C8;PTGS1;CYP2E1;ALB;ABCB1 common genes common pathways GO:0008283| cell proliferation TSPO;MET GO:0007165| signal transduction GABRE;GABRQ;GABRP;GABRB3;TSPO;MET;GABRA6;GABRB1;GABRD;GABRR2;GABRA5 43654:[DB06314 DB06602] DB06314|SGX-523 MET DB06602|Reslizumab IL5 common genes common pathways GO:0018108| peptidyl-tyrosine phosphorylation MET;IL5 GO:0000165| MAPKKK cascade MET;IL5 43655:[DB06314 DB00864] DB06314|SGX-523 MET DB00864|Tacrolimus FKBP1A;CYP3A7;CYP3A5;CYP3A4;ALB;ORM1;ABCB1;ABCA5;SLCO1B1 common genes common pathways 43656:[DB06314 DB08059] DB06314|SGX-523 MET DB08059|Wortmannin PIK3CG;PLK1;PIK3R1;PIK3CA common genes common pathways GO:0046854| phosphatidylinositol phosphorylation PIK3CA;MET;PIK3R1;PIK3CG GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PIK3R1 GO:0051897| positive regulation of protein kinase B signaling cascade PIK3CA;PIK3R1;PIK3CG;MET GO:0016310| phosphorylation PLK1;PIK3CG;MET;PIK3CA GO:0006468| protein phosphorylation PIK3CA;PIK3R1;PIK3CG;PLK1;MET GO:0007165| signal transduction PIK3R1;MET GO:0008283| cell proliferation PLK1;MET 43657:[DB06314 DB00734] DB06314|SGX-523 MET DB00734|Risperidone HTR2A;DRD2;DRD3;DRD4;ADRA1A;ADRA1B;HTR1D;HRH1;ADRA2A;ADRA2B;ADRA2C;HTR2C;HTR1A;DRD1;HTR7;CYP2D6;CYP3A4;CYP3A5;CYP3A7 common genes common pathways GO:0007165| signal transduction DRD3;HTR7;MET;HRH1;ADRA2C;ADRA2A;HTR2C;HTR1D;HTR1A;ADRA1B;DRD4;ADRA2B;HTR2A;DRD1;DRD2;ADRA1A GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET GO:0008283| cell proliferation HTR1A;ADRA1B;MET GO:0010507| negative regulation of autophagy ADRA1A;MET GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;DRD3;DRD2 43658:[DB06314 DB12874] DB06314|SGX-523 MET DB12874|Quizartinib FLT3 common genes common pathways GO:0016310| phosphorylation FLT3;MET GO:0007169| transmembrane receptor protein tyrosine kinase signaling pathway FLT3;MET GO:0006468| protein phosphorylation MET;FLT3 GO:0018108| peptidyl-tyrosine phosphorylation FLT3;MET 43659:[DB06314 DB08794] DB06314|SGX-523 MET DB08794|Ethyl biscoumacetate GLUL;CYP3A4 common genes common pathways GO:0008283| cell proliferation MET;GLUL 43660:[DB06314 DB05750] DB06314|SGX-523 MET DB05750|AVE-1625 CNR1 common genes common pathways GO:0007165| signal transduction MET;CNR1 43661:[DB06314 DB00465] DB06314|SGX-523 MET DB00465|Ketorolac PTGS2;PTGS1 common genes common pathways 43662:[DB06314 DB00720] DB06314|SGX-523 MET DB00720|Clodronic acid SLC25A4;SLC25A5;SLC25A6;PTGS2 common genes common pathways 43663:[DB06314 DB00653] DB06314|SGX-523 MET DB00653|Magnesium sulfate CACNG1;CACNA2D1;CACNA1C;CACNB1;CACNB2;CACNA1S common genes common pathways 43664:[DB06314 DB01147] DB06314|SGX-523 MET DB01147|Cloxacillin ALB;SLC15A1;SLC15A2;SLC22A6 common genes common pathways 43665:[DB06314 DB00573] DB06314|SGX-523 MET DB00573|Fenoprofen PTGS2;PTGS1;PPARA;PPARG;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARA;PPARG GO:0007165| signal transduction MET;PPARG 43666:[DB06314 DB00120] DB06314|SGX-523 MET DB00120|L-Phenylalanine TAT;SLC7A8;FARSA;PAH;FARS2;FARSB;TH;SLC16A10 common genes common pathways 43667:[DB06314 DB09329] DB06314|SGX-523 MET DB09329|Antihemophilic Factor (Recombinant), PEGylated VWF;VWF common genes common pathways 43668:[DB06314 DB00788] DB06314|SGX-523 MET DB00788|Naproxen PTGS1;PTGS2;CYP2C9;CYP1A2;CYP2C8;UGT1A1;UGT2B7;ALB;SLCO1A2;SLC22A6;ABCB11 common genes common pathways 43669:[DB06314 DB01267] DB06314|SGX-523 MET DB01267|Paliperidone HTR2A;DRD2;HRH1;ADRA1A;ADRA1B;DRD4;HTR1D;DRD3;HTR2C;ADRA2A;ADRA2B;ADRA2C;HTR1A;DRD1;HTR7;CYP3A4;CYP2D6;CYP3A5;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD3;MET;DRD2 GO:0007165| signal transduction HTR1A;HTR1D;ADRA1B;DRD4;ADRA2B;HTR2A;DRD1;ADRA1A;DRD2;DRD3;HTR7;ADRA2C;MET;HRH1;ADRA2A;HTR2C GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0008283| cell proliferation HTR1A;ADRA1B;MET GO:0010507| negative regulation of autophagy MET;ADRA1A 43670:[DB06314 DB00224] DB06314|SGX-523 MET DB00224|Indinavir pol;CYP3A4;CYP3A7;CYP3A5;CYP2D6;UGT1A1;ABCB1;SLC22A1;ABCC1;SLCO1A2;SLCO1B1;ABCC2;SLCO2B1;ABCB11 common genes common pathways 43671:[DB06314 DB00869] DB06314|SGX-523 MET DB00869|Dorzolamide CA2;CA4;CA1;CA3;CYP2C9;CYP3A4 common genes common pathways 43672:[DB06314 DB06674] DB06314|SGX-523 MET DB06674|Golimumab TNF common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TNF;MET GO:0051897| positive regulation of protein kinase B signaling cascade TNF;MET GO:0000165| MAPKKK cascade TNF;MET 43673:[DB06314 DB11636] DB06314|SGX-523 MET DB11636|Nomegestrol CYP3A4 common genes common pathways 43674:[DB06314 DB00998] DB06314|SGX-523 MET DB00998|Frovatriptan HTR1D;HTR1B;CYP1A2 common genes common pathways GO:0007165| signal transduction HTR1D;HTR1B;MET 43675:[DB06314 DB00133] DB06314|SGX-523 MET DB00133|Serine CBS;SDS;SRR;SPTLC2;SPTLC1;SARS;AGXT;SLC16A10 common genes common pathways 43676:[DB06314 DB13749] DB06314|SGX-523 MET DB13749|Magnesium gluconate CKB;ABL1;ADCY1;GUCY1A2;PFKFB1;ATP1A1 common genes common pathways GO:0006468| protein phosphorylation MET;ABL1 GO:0016310| phosphorylation PFKFB1;CKB;ABL1;MET GO:0007165| signal transduction GUCY1A2;MET;ADCY1 GO:0018108| peptidyl-tyrosine phosphorylation MET;ABL1 43677:[DB06314 DB12089] DB06314|SGX-523 MET DB12089|Lorvotuzumab mertansine CYP3A4 common genes common pathways 43678:[DB06314 DB07173] DB06314|SGX-523 MET DB07173|7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE ADK common genes common pathways GO:0016310| phosphorylation ADK;MET 43679:[DB06314 DB00539] DB06314|SGX-523 MET DB00539|Toremifene ESR1;SHBG;CYP3A4;CYP1A1;ABCB1 common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter ESR1;MET GO:0007165| signal transduction MET;ESR1 GO:0008283| cell proliferation CYP1A1;MET 43680:[DB06314 DB09061] DB06314|SGX-523 MET DB09061|Cannabidiol CNR1;CNR2;GPR12;GLRA1;GLRA1;GLRB;GLRA3;GPR18;GPR55;HTR1A;HTR2A;CHRNA7;OPRD1;OPRM1;PPARG;TRPV1;CACNA1G;CACNA1H;CACNA1I;TRPA1;TRPM8;TRPV2;TRPV3;TRPV4;VDAC1;HTR3A;ADORA1;CYP2C9;CYP2C19;CYP2D6;CYP3A4;CYP3A5;ACAT1;AANAT;CAT;PTGS1;PTGS2;CYP3A7;CYP1A1;CYP1A2;CYP1B1;DAGLA;FAAH;GSR;GPX1;HMGCR;IDO1;ALOX5;ALOX15;NAAA;CRYZ;NAPEPLD;PLA2G1B;CYP17A1;SOD1;SMPD1;ABCC1;ABCG2;SLC29A1 common genes common pathways GO:0051897| positive regulation of protein kinase B signaling cascade MET;GPX1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;PPARG;PLA2G1B GO:0008283| cell proliferation MET;GPX1;CYP1A1;HTR1A GO:0007165| signal transduction HTR2A;CNR2;HTR3A;HTR1A;GPR55;OPRD1;CHRNA7;GPR18;SMPD1;GPR12;MET;ADORA1;CACNA1I;CNR1;OPRM1;PPARG;PLA2G1B GO:0007166| cell surface receptor linked signaling pathway TRPV1;MET;TRPA1 43681:[DB06314 DB00066] DB06314|SGX-523 MET DB00066|Follitropin FSHR common genes common pathways GO:0007165| signal transduction MET;FSHR 43682:[DB06314 DB01873] DB06314|SGX-523 MET DB01873|Epothilone D TUBA3C;TUBB;TUBB1;TUBB4B;TUBB4A;TUBA4A;TUBB3;TUBA1C;TUBA8;TUBA1B;TUBA1A;CYP3A4 common genes common pathways 43683:[DB06314 DB11595] DB06314|SGX-523 MET DB11595|Atezolizumab CD274 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;CD274 GO:0007165| signal transduction CD274;MET 43684:[DB06314 DB11135] DB06314|SGX-523 MET DB11135|Selenium SCLY;GSR;TXNRD1 common genes common pathways GO:0008283| cell proliferation TXNRD1;MET GO:0007165| signal transduction TXNRD1;MET 43685:[DB06314 DB00950] DB06314|SGX-523 MET DB00950|Fexofenadine HRH1;ABCB1;SLCO2B1;SLCO1A2;SLCO1B1;SLCO1B3;SLC22A8 common genes common pathways GO:0007165| signal transduction HRH1;MET 43686:[DB06314 DB01582] DB06314|SGX-523 MET DB01582|Sulfamethazine ALB common genes common pathways 43687:[DB06314 DB00397] DB06314|SGX-523 MET DB00397|Phenylpropanolamine DRD1;ADRB1;ADRB2;ADRA2A;ADRA2B;ADRA2C;MAOA common genes common pathways GO:0007165| signal transduction MET;ADRB2;ADRA2C;ADRA2A;ADRB1;ADRA2B;DRD1 GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43688:[DB06314 DB00908] DB06314|SGX-523 MET DB00908|Quinidine SCN5A;KCNK1;KCNK6;KCNH2;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP3A7;CYP2D6;CYP1A2;CYP2E1;CYP1A1;CYP2B6;CYP2C9;CYP2C8;ORM1;SLC22A2;SLC22A1;SLC22A5;ABCB1;SLCO1A2;SLC22A8;ABCC2;SLC22A4;SLCO1B1;ABCB11 common genes common pathways GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0007165| signal transduction MET;ADRA1D;ADRA1A;ADRA1B GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation CYP1A1;ADRA1B;MET;ADRA1D 43689:[DB06314 DB05012] DB06314|SGX-523 MET DB05012|XEN2174 SLC6A2 common genes common pathways 43690:[DB06314 DB00728] DB06314|SGX-523 MET DB00728|Rocuronium CHRNA2;CHRM2;HTR3A;SLC22A1;SLCO1A2 common genes common pathways GO:0007165| signal transduction CHRNA2;HTR3A;CHRM2;MET 43691:[DB06314 DB13876] DB06314|SGX-523 MET DB13876|Brofaromine MAOA common genes common pathways 43692:[DB06314 DB09047] DB06314|SGX-523 MET DB09047|Finafloxacin gyrA;parC;TOP2A common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter TOP2A;MET 43693:[DB06314 DB00643] DB06314|SGX-523 MET DB00643|Mebendazole TUBA1A;TUBB4B;CYP3A4;CYP1A1 common genes common pathways GO:0008283| cell proliferation CYP1A1;MET 43694:[DB06314 DB00612] DB06314|SGX-523 MET DB00612|Bisoprolol ADRB1;ADRB2;CYP3A4;CYP2D6 common genes common pathways GO:0007166| cell surface receptor linked signaling pathway MET;ADRB2 GO:0007165| signal transduction MET;ADRB2;ADRB1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter ADRB2;MET 43695:[DB06314 DB00213] DB06314|SGX-523 MET DB00213|Pantoprazole ATP4A;CYP2C19;CYP3A4;ABCB1;ABCG2;SLCO1B1 common genes common pathways 43696:[DB06314 DB08922] DB06314|SGX-523 MET DB08922|Perospirone HTR2A;DRD2;HTR1A;HRH1;DRD4;ADRA1A;ADRA1B;ADRA1D;CYP3A4;CYP2D6;CYP2C8;CYP1A1 common genes common pathways GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1D;MET;HTR1A;ADRA1B;CYP1A1 GO:0007165| signal transduction HTR2A;DRD4;ADRA1A;DRD2;HTR1A;ADRA1B;HRH1;MET;ADRA1D GO:0035024| negative regulation of Rho protein signal transduction MET;ADRA1A GO:0045944| positive regulation of transcription from RNA polymerase II promoter DRD2;MET 43697:[DB06314 DB01576] DB06314|SGX-523 MET DB01576|Dextroamphetamine SLC18A2;SLC6A2;SLC6A3;TAAR1;ADRA1A;ADRA1B common genes common pathways GO:0010507| negative regulation of autophagy MET;ADRA1A GO:0008283| cell proliferation ADRA1B;MET GO:0007165| signal transduction TAAR1;ADRA1B;ADRA1A;MET GO:0035024| negative regulation of Rho protein signal transduction ADRA1A;MET 43698:[DB06314 DB01068] DB06314|SGX-523 MET DB01068|Clonazepam GABRA1;GABRA2;GABRA3;GABRA4;GABRA5;GABRA6;GABRB1;GABRB2;GABRB3;GABRD;GABRE;GABRG1;GABRG2;GABRG3;GABRP;GABRQ;TSPO;NR1I2;CYP3A4;CYP2E1;NAT2;ALB common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR1I2;MET GO:0007165| signal transduction NR1I2;MET;TSPO;GABRB3;GABRP;GABRQ;GABRE;GABRA5;GABRD;GABRB1;GABRA6 GO:0008283| cell proliferation TSPO;MET 43699:[DB06314 DB03615] DB06314|SGX-523 MET DB03615|Ribostamycin P4HB;rpsL common genes common pathways 43700:[DB06314 DB00647] DB06314|SGX-523 MET DB00647|Dextropropoxyphene OPRM1;OPRD1;OPRK1;CES1;CYP3A4;CYP2D6;CYP2C8 common genes common pathways GO:0007165| signal transduction MET;OPRK1;OPRM1;OPRD1 43701:[DB06314 DB11560] DB06314|SGX-523 MET DB11560|Lesinurad SLC22A12;SLC22A11;CYP2C9 common genes common pathways 43702:[DB06314 DB13999] DB06314|SGX-523 MET DB13999|Moroctocog alfa F10;PHYH;F9;ASGR2;HSPA5;CALR;CANX;LMAN1;LRP1;MCFD2;VWF;F2;PROC common genes common pathways GO:0008283| cell proliferation LRP1;MET GO:0007166| cell surface receptor linked signaling pathway F2;MET;ASGR2 GO:0051897| positive regulation of protein kinase B signaling cascade MET;F10 43703:[DB06314 DB11598] DB06314|SGX-523 MET DB11598|Antithrombin III human SERPINC1 common genes common pathways 43704:[DB06314 DB11450] DB06314|SGX-523 MET DB11450|Pimobendan CYP1A2 common genes common pathways 43705:[DB06314 DB02236] DB06314|SGX-523 MET DB02236|Glycinamide Ribonucleotide GART common genes common pathways 43706:[DB06314 DB00270] DB06314|SGX-523 MET DB00270|Isradipine CACNA1C;CACNA2D1;CACNB2;CACNA1H;CACNA2D2;CACNA1D;CACNA1S;CYP3A4;ABCB11 common genes common pathways 43707:[DB06314 DB00606] DB06314|SGX-523 MET DB00606|Cyclothiazide FXYD2;CA1;CA2;CA4;SFRP4;SLC22A6 common genes common pathways 43708:[DB06314 DB08971] DB06314|SGX-523 MET DB08971|Fluocortolone CYP3A4 common genes common pathways 43709:[DB06314 DB00999] DB06314|SGX-523 MET DB00999|Hydrochlorothiazide SLC12A3;CA1;CA2;KCNMA1;SLC22A6 common genes common pathways 43710:[DB06314 DB06691] DB06314|SGX-523 MET DB06691|Mepyramine HRH1;CYP2D6;SLC22A4;SLC22A5 common genes common pathways GO:0007165| signal transduction HRH1;MET 43711:[DB06314 DB13488] DB06314|SGX-523 MET DB13488|Bencyclane CYP3A4 common genes common pathways 43712:[DB06314 DB00741] DB06314|SGX-523 MET DB00741|Hydrocortisone NR3C1;ANXA1;HSD11B2;HSD3B1;CYP3A4;CYP3A5;CYP3A7;CYP11B1;CYP11B2;CYP2C8;SHBG;SERPINA6;ABCB1;ABCG2;SLCO1A2;SLC22A8 common genes common pathways GO:0007165| signal transduction NR3C1;MET;ANXA1 GO:0007166| cell surface receptor linked signaling pathway MET;ANXA1 GO:0045944| positive regulation of transcription from RNA polymerase II promoter NR3C1;MET 43713:[DB06314 DB06210] DB06314|SGX-523 MET DB06210|Eltrombopag MPL;CYP2C8;CYP1A2;UGT1A1;UGT1A3;UGT1A9;SLCO1B1;ABCG2 common genes common pathways GO:0008283| cell proliferation MPL;MET GO:0007166| cell surface receptor linked signaling pathway MPL;MET 43714:[DB06314 DB08872] DB06314|SGX-523 MET DB08872|Gabapentin enacarbil CACNA2D1;CACNA2D2;SLC5A8;SLC5A6 common genes common pathways 43715:[DB06314 DB06421] DB06314|SGX-523 MET DB06421|Declopramide TOP2A;TOP2B common genes common pathways GO:0045944| positive regulation of transcription from RNA polymerase II promoter MET;TOP2A 43716:[DB06314 DB13133] DB06314|SGX-523 MET DB13133|Von Willebrand Factor Human F8;COL1A1;ADAMTS13 common genes common pathways 43717:[DB06314 DB00233] DB06314|SGX-523 MET DB00233|Aminosalicylic Acid PTGS2;CHUK;ALOX5;PLA2G2E;folK;MPO common genes common pathways GO:0006468| protein phosphorylation CHUK;MET GO:0016310| phosphorylation MET;CHUK GO:0045944| positive regulation of transcription from RNA polymerase II promoter CHUK;MET 43718:[DB06314 DB11606] DB06314|SGX-523 MET DB11606|Susoctocog alfa VWF common genes common pathways 43719:[DB06314 DB05155] DB06314|SGX-523 MET DB05155|CR665 OPRK1 common genes common pathways GO:0007165| signal transduction OPRK1;MET